data_9CG4
# 
_entry.id   9CG4 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CG4         pdb_00009cg4 10.2210/pdb9cg4/pdb 
WWPDB D_1000285412 ?            ?                   
EMDB  EMD-45568    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-19 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CG4 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-28 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Cryo-EM structure of FAN1, PCNA and DNA substrate with (CAG)2 extrusion in intermediate state' 
_pdbx_database_related.db_id          EMD-45568 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              anna.pluciennik@jefferson.edu 
_pdbx_contact_author.name_first         Anna 
_pdbx_contact_author.name_last          Pluciennik 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-4868-6024 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Fenglin, L.' 1 0000-0001-7932-0071 
'Anna, P.'    2 0000-0003-4868-6024 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'cryo-EM structure of FAN1-PCNA-DNA complex in intermediate state' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Fenglin, L.' 1 0000-0001-7932-0071 
primary 'Anna, P.'    2 ?                   
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Proliferating cell nuclear antigen'                                                   28795.752 3 ?                
? ? ? 
2 polymer man 'Fanconi-associated nuclease 1'                                                        20853.436 1 3.1.21.-,3.1.4.1 
? ? ? 
3 polymer syn 
;DNA (5'-D(P*CP*GP*AP*AP*TP*TP*TP*CP*TP*AP*GP*AP*CP*TP*CP*GP*AP*GP*AP*TP*CP*AP*G)-3')
;
7064.585  1 ?                ? ? ? 
4 polymer syn 
;DNA (5'-D(P*AP*TP*CP*TP*CP*GP*AP*GP*TP*CP*TP*AP*GP*AP*AP*AP*TP*TP*CP*G)-3')
;
6132.991  1 ?                ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 PCNA,Cyclin                                                                
2 'FANCD2/FANCI-associated nuclease 1,hFAN1,Myotubularin-related protein 15' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'        no no 
;MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILK
CAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVI
SCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYK
IADMGHLKYYLAPKIEDEEGS
;
;MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILK
CAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVI
SCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYK
IADMGHLKYYLAPKIEDEEGS
;
B,C,D ? 
2 'polypeptide(L)'        no no 
;HPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELT
NAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALA
GQSVRICKGPRAVFSRILLLFSL
;
;HPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELT
NAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALA
GQSVRICKGPRAVFSRILLLFSL
;
E     ? 
3 polydeoxyribonucleotide no no 
;(DC)(DG)(DA)(DA)(DT)(DT)(DT)(DC)(DT)(DA)(DG)(DA)(DC)(DT)(DC)(DG)(DA)(DG)(DA)(DT)
(DC)(DA)(DG)
;
CGAATTTCTAGACTCGAGATCAG A     ? 
4 polydeoxyribonucleotide no no '(DA)(DT)(DC)(DT)(DC)(DG)(DA)(DG)(DT)(DC)(DT)(DA)(DG)(DA)(DA)(DA)(DT)(DT)(DC)(DG)' 
ATCTCGAGTCTAGAAATTCG F     ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   PHE n 
1 3   GLU n 
1 4   ALA n 
1 5   ARG n 
1 6   LEU n 
1 7   VAL n 
1 8   GLN n 
1 9   GLY n 
1 10  SER n 
1 11  ILE n 
1 12  LEU n 
1 13  LYS n 
1 14  LYS n 
1 15  VAL n 
1 16  LEU n 
1 17  GLU n 
1 18  ALA n 
1 19  LEU n 
1 20  LYS n 
1 21  ASP n 
1 22  LEU n 
1 23  ILE n 
1 24  ASN n 
1 25  GLU n 
1 26  ALA n 
1 27  CYS n 
1 28  TRP n 
1 29  ASP n 
1 30  ILE n 
1 31  SER n 
1 32  SER n 
1 33  SER n 
1 34  GLY n 
1 35  VAL n 
1 36  ASN n 
1 37  LEU n 
1 38  GLN n 
1 39  SER n 
1 40  MET n 
1 41  ASP n 
1 42  SER n 
1 43  SER n 
1 44  HIS n 
1 45  VAL n 
1 46  SER n 
1 47  LEU n 
1 48  VAL n 
1 49  GLN n 
1 50  LEU n 
1 51  THR n 
1 52  LEU n 
1 53  ARG n 
1 54  SER n 
1 55  GLU n 
1 56  GLY n 
1 57  PHE n 
1 58  ASP n 
1 59  THR n 
1 60  TYR n 
1 61  ARG n 
1 62  CYS n 
1 63  ASP n 
1 64  ARG n 
1 65  ASN n 
1 66  LEU n 
1 67  ALA n 
1 68  MET n 
1 69  GLY n 
1 70  VAL n 
1 71  ASN n 
1 72  LEU n 
1 73  THR n 
1 74  SER n 
1 75  MET n 
1 76  SER n 
1 77  LYS n 
1 78  ILE n 
1 79  LEU n 
1 80  LYS n 
1 81  CYS n 
1 82  ALA n 
1 83  GLY n 
1 84  ASN n 
1 85  GLU n 
1 86  ASP n 
1 87  ILE n 
1 88  ILE n 
1 89  THR n 
1 90  LEU n 
1 91  ARG n 
1 92  ALA n 
1 93  GLU n 
1 94  ASP n 
1 95  ASN n 
1 96  ALA n 
1 97  ASP n 
1 98  THR n 
1 99  LEU n 
1 100 ALA n 
1 101 LEU n 
1 102 VAL n 
1 103 PHE n 
1 104 GLU n 
1 105 ALA n 
1 106 PRO n 
1 107 ASN n 
1 108 GLN n 
1 109 GLU n 
1 110 LYS n 
1 111 VAL n 
1 112 SER n 
1 113 ASP n 
1 114 TYR n 
1 115 GLU n 
1 116 MET n 
1 117 LYS n 
1 118 LEU n 
1 119 MET n 
1 120 ASP n 
1 121 LEU n 
1 122 ASP n 
1 123 VAL n 
1 124 GLU n 
1 125 GLN n 
1 126 LEU n 
1 127 GLY n 
1 128 ILE n 
1 129 PRO n 
1 130 GLU n 
1 131 GLN n 
1 132 GLU n 
1 133 TYR n 
1 134 SER n 
1 135 CYS n 
1 136 VAL n 
1 137 VAL n 
1 138 LYS n 
1 139 MET n 
1 140 PRO n 
1 141 SER n 
1 142 GLY n 
1 143 GLU n 
1 144 PHE n 
1 145 ALA n 
1 146 ARG n 
1 147 ILE n 
1 148 CYS n 
1 149 ARG n 
1 150 ASP n 
1 151 LEU n 
1 152 SER n 
1 153 HIS n 
1 154 ILE n 
1 155 GLY n 
1 156 ASP n 
1 157 ALA n 
1 158 VAL n 
1 159 VAL n 
1 160 ILE n 
1 161 SER n 
1 162 CYS n 
1 163 ALA n 
1 164 LYS n 
1 165 ASP n 
1 166 GLY n 
1 167 VAL n 
1 168 LYS n 
1 169 PHE n 
1 170 SER n 
1 171 ALA n 
1 172 SER n 
1 173 GLY n 
1 174 GLU n 
1 175 LEU n 
1 176 GLY n 
1 177 ASN n 
1 178 GLY n 
1 179 ASN n 
1 180 ILE n 
1 181 LYS n 
1 182 LEU n 
1 183 SER n 
1 184 GLN n 
1 185 THR n 
1 186 SER n 
1 187 ASN n 
1 188 VAL n 
1 189 ASP n 
1 190 LYS n 
1 191 GLU n 
1 192 GLU n 
1 193 GLU n 
1 194 ALA n 
1 195 VAL n 
1 196 THR n 
1 197 ILE n 
1 198 GLU n 
1 199 MET n 
1 200 ASN n 
1 201 GLU n 
1 202 PRO n 
1 203 VAL n 
1 204 GLN n 
1 205 LEU n 
1 206 THR n 
1 207 PHE n 
1 208 ALA n 
1 209 LEU n 
1 210 ARG n 
1 211 TYR n 
1 212 LEU n 
1 213 ASN n 
1 214 PHE n 
1 215 PHE n 
1 216 THR n 
1 217 LYS n 
1 218 ALA n 
1 219 THR n 
1 220 PRO n 
1 221 LEU n 
1 222 SER n 
1 223 SER n 
1 224 THR n 
1 225 VAL n 
1 226 THR n 
1 227 LEU n 
1 228 SER n 
1 229 MET n 
1 230 SER n 
1 231 ALA n 
1 232 ASP n 
1 233 VAL n 
1 234 PRO n 
1 235 LEU n 
1 236 VAL n 
1 237 VAL n 
1 238 GLU n 
1 239 TYR n 
1 240 LYS n 
1 241 ILE n 
1 242 ALA n 
1 243 ASP n 
1 244 MET n 
1 245 GLY n 
1 246 HIS n 
1 247 LEU n 
1 248 LYS n 
1 249 TYR n 
1 250 TYR n 
1 251 LEU n 
1 252 ALA n 
1 253 PRO n 
1 254 LYS n 
1 255 ILE n 
1 256 GLU n 
1 257 ASP n 
1 258 GLU n 
1 259 GLU n 
1 260 GLY n 
1 261 SER n 
2 1   HIS n 
2 2   PRO n 
2 3   TYR n 
2 4   TYR n 
2 5   LEU n 
2 6   ARG n 
2 7   SER n 
2 8   PHE n 
2 9   LEU n 
2 10  VAL n 
2 11  VAL n 
2 12  LEU n 
2 13  LYS n 
2 14  THR n 
2 15  VAL n 
2 16  LEU n 
2 17  GLU n 
2 18  ASN n 
2 19  GLU n 
2 20  ASP n 
2 21  ASP n 
2 22  MET n 
2 23  LEU n 
2 24  LEU n 
2 25  PHE n 
2 26  ASP n 
2 27  GLU n 
2 28  GLN n 
2 29  GLU n 
2 30  LYS n 
2 31  GLY n 
2 32  ILE n 
2 33  VAL n 
2 34  THR n 
2 35  LYS n 
2 36  PHE n 
2 37  TYR n 
2 38  GLN n 
2 39  LEU n 
2 40  SER n 
2 41  ALA n 
2 42  THR n 
2 43  GLY n 
2 44  GLN n 
2 45  LYS n 
2 46  LEU n 
2 47  TYR n 
2 48  VAL n 
2 49  ARG n 
2 50  LEU n 
2 51  PHE n 
2 52  GLN n 
2 53  ARG n 
2 54  LYS n 
2 55  LEU n 
2 56  SER n 
2 57  TRP n 
2 58  ILE n 
2 59  LYS n 
2 60  MET n 
2 61  THR n 
2 62  LYS n 
2 63  LEU n 
2 64  GLU n 
2 65  TYR n 
2 66  GLU n 
2 67  GLU n 
2 68  ILE n 
2 69  ALA n 
2 70  LEU n 
2 71  ASP n 
2 72  LEU n 
2 73  THR n 
2 74  PRO n 
2 75  VAL n 
2 76  ILE n 
2 77  GLU n 
2 78  GLU n 
2 79  LEU n 
2 80  THR n 
2 81  ASN n 
2 82  ALA n 
2 83  GLY n 
2 84  PHE n 
2 85  LEU n 
2 86  GLN n 
2 87  THR n 
2 88  GLU n 
2 89  SER n 
2 90  GLU n 
2 91  LEU n 
2 92  GLN n 
2 93  GLU n 
2 94  LEU n 
2 95  SER n 
2 96  GLU n 
2 97  VAL n 
2 98  LEU n 
2 99  GLU n 
2 100 LEU n 
2 101 LEU n 
2 102 SER n 
2 103 ALA n 
2 104 PRO n 
2 105 GLU n 
2 106 LEU n 
2 107 LYS n 
2 108 SER n 
2 109 LEU n 
2 110 ALA n 
2 111 LYS n 
2 112 THR n 
2 113 PHE n 
2 114 HIS n 
2 115 LEU n 
2 116 VAL n 
2 117 ASN n 
2 118 PRO n 
2 119 ASN n 
2 120 GLY n 
2 121 GLN n 
2 122 LYS n 
2 123 GLN n 
2 124 GLN n 
2 125 LEU n 
2 126 VAL n 
2 127 ASP n 
2 128 ALA n 
2 129 PHE n 
2 130 LEU n 
2 131 LYS n 
2 132 LEU n 
2 133 ALA n 
2 134 LYS n 
2 135 GLN n 
2 136 ARG n 
2 137 SER n 
2 138 VAL n 
2 139 CYS n 
2 140 THR n 
2 141 TRP n 
2 142 GLY n 
2 143 LYS n 
2 144 ASN n 
2 145 LYS n 
2 146 PRO n 
2 147 GLY n 
2 148 ILE n 
2 149 GLY n 
2 150 ALA n 
2 151 VAL n 
2 152 ILE n 
2 153 LEU n 
2 154 LYS n 
2 155 ARG n 
2 156 ALA n 
2 157 LYS n 
2 158 ALA n 
2 159 LEU n 
2 160 ALA n 
2 161 GLY n 
2 162 GLN n 
2 163 SER n 
2 164 VAL n 
2 165 ARG n 
2 166 ILE n 
2 167 CYS n 
2 168 LYS n 
2 169 GLY n 
2 170 PRO n 
2 171 ARG n 
2 172 ALA n 
2 173 VAL n 
2 174 PHE n 
2 175 SER n 
2 176 ARG n 
2 177 ILE n 
2 178 LEU n 
2 179 LEU n 
2 180 LEU n 
2 181 PHE n 
2 182 SER n 
2 183 LEU n 
3 1   DC  n 
3 2   DG  n 
3 3   DA  n 
3 4   DA  n 
3 5   DT  n 
3 6   DT  n 
3 7   DT  n 
3 8   DC  n 
3 9   DT  n 
3 10  DA  n 
3 11  DG  n 
3 12  DA  n 
3 13  DC  n 
3 14  DT  n 
3 15  DC  n 
3 16  DG  n 
3 17  DA  n 
3 18  DG  n 
3 19  DA  n 
3 20  DT  n 
3 21  DC  n 
3 22  DA  n 
3 23  DG  n 
4 1   DA  n 
4 2   DT  n 
4 3   DC  n 
4 4   DT  n 
4 5   DC  n 
4 6   DG  n 
4 7   DA  n 
4 8   DG  n 
4 9   DT  n 
4 10  DC  n 
4 11  DT  n 
4 12  DA  n 
4 13  DG  n 
4 14  DA  n 
4 15  DA  n 
4 16  DA  n 
4 17  DT  n 
4 18  DT  n 
4 19  DC  n 
4 20  DG  n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 261 human ? PCNA                     ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 183 human ? 'FAN1, KIAA1018, MTMR15' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_pdbx_entity_src_syn.entity_id 
_pdbx_entity_src_syn.pdbx_src_id 
_pdbx_entity_src_syn.pdbx_alt_source_flag 
_pdbx_entity_src_syn.pdbx_beg_seq_num 
_pdbx_entity_src_syn.pdbx_end_seq_num 
_pdbx_entity_src_syn.organism_scientific 
_pdbx_entity_src_syn.organism_common_name 
_pdbx_entity_src_syn.ncbi_taxonomy_id 
_pdbx_entity_src_syn.details 
3 1 sample 1 23 'synthetic construct' ? 32630  ? 
4 1 sample 1 20 'synthetic construct' ? 326630 ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                              ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                             ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                           ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                      ? 'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE                             ? 'C3 H7 N O2 S'    121.158 
DA  'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O6 P' 331.222 
DC  'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O7 P'  307.197 
DG  'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
DT  'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE"         ? 'C10 H15 N2 O8 P' 322.208 
GLN 'L-peptide linking' y GLUTAMINE                            ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                      ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                              ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                            ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                           ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                              ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                               ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                           ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                        ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                              ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                               ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                            ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                           ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                             ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                               ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET B . n 
A 1 2   PHE 2   2   2   PHE PHE B . n 
A 1 3   GLU 3   3   3   GLU GLU B . n 
A 1 4   ALA 4   4   4   ALA ALA B . n 
A 1 5   ARG 5   5   5   ARG ARG B . n 
A 1 6   LEU 6   6   6   LEU LEU B . n 
A 1 7   VAL 7   7   7   VAL VAL B . n 
A 1 8   GLN 8   8   8   GLN GLN B . n 
A 1 9   GLY 9   9   9   GLY GLY B . n 
A 1 10  SER 10  10  10  SER SER B . n 
A 1 11  ILE 11  11  11  ILE ILE B . n 
A 1 12  LEU 12  12  12  LEU LEU B . n 
A 1 13  LYS 13  13  13  LYS LYS B . n 
A 1 14  LYS 14  14  14  LYS LYS B . n 
A 1 15  VAL 15  15  15  VAL VAL B . n 
A 1 16  LEU 16  16  16  LEU LEU B . n 
A 1 17  GLU 17  17  17  GLU GLU B . n 
A 1 18  ALA 18  18  18  ALA ALA B . n 
A 1 19  LEU 19  19  19  LEU LEU B . n 
A 1 20  LYS 20  20  20  LYS LYS B . n 
A 1 21  ASP 21  21  21  ASP ASP B . n 
A 1 22  LEU 22  22  22  LEU LEU B . n 
A 1 23  ILE 23  23  23  ILE ILE B . n 
A 1 24  ASN 24  24  24  ASN ASN B . n 
A 1 25  GLU 25  25  25  GLU GLU B . n 
A 1 26  ALA 26  26  26  ALA ALA B . n 
A 1 27  CYS 27  27  27  CYS CYS B . n 
A 1 28  TRP 28  28  28  TRP TRP B . n 
A 1 29  ASP 29  29  29  ASP ASP B . n 
A 1 30  ILE 30  30  30  ILE ILE B . n 
A 1 31  SER 31  31  31  SER SER B . n 
A 1 32  SER 32  32  32  SER SER B . n 
A 1 33  SER 33  33  33  SER SER B . n 
A 1 34  GLY 34  34  34  GLY GLY B . n 
A 1 35  VAL 35  35  35  VAL VAL B . n 
A 1 36  ASN 36  36  36  ASN ASN B . n 
A 1 37  LEU 37  37  37  LEU LEU B . n 
A 1 38  GLN 38  38  38  GLN GLN B . n 
A 1 39  SER 39  39  39  SER SER B . n 
A 1 40  MET 40  40  40  MET MET B . n 
A 1 41  ASP 41  41  41  ASP ASP B . n 
A 1 42  SER 42  42  42  SER SER B . n 
A 1 43  SER 43  43  43  SER SER B . n 
A 1 44  HIS 44  44  44  HIS HIS B . n 
A 1 45  VAL 45  45  45  VAL VAL B . n 
A 1 46  SER 46  46  46  SER SER B . n 
A 1 47  LEU 47  47  47  LEU LEU B . n 
A 1 48  VAL 48  48  48  VAL VAL B . n 
A 1 49  GLN 49  49  49  GLN GLN B . n 
A 1 50  LEU 50  50  50  LEU LEU B . n 
A 1 51  THR 51  51  51  THR THR B . n 
A 1 52  LEU 52  52  52  LEU LEU B . n 
A 1 53  ARG 53  53  53  ARG ARG B . n 
A 1 54  SER 54  54  54  SER SER B . n 
A 1 55  GLU 55  55  55  GLU GLU B . n 
A 1 56  GLY 56  56  56  GLY GLY B . n 
A 1 57  PHE 57  57  57  PHE PHE B . n 
A 1 58  ASP 58  58  58  ASP ASP B . n 
A 1 59  THR 59  59  59  THR THR B . n 
A 1 60  TYR 60  60  60  TYR TYR B . n 
A 1 61  ARG 61  61  61  ARG ARG B . n 
A 1 62  CYS 62  62  62  CYS CYS B . n 
A 1 63  ASP 63  63  63  ASP ASP B . n 
A 1 64  ARG 64  64  64  ARG ARG B . n 
A 1 65  ASN 65  65  65  ASN ASN B . n 
A 1 66  LEU 66  66  66  LEU LEU B . n 
A 1 67  ALA 67  67  67  ALA ALA B . n 
A 1 68  MET 68  68  68  MET MET B . n 
A 1 69  GLY 69  69  69  GLY GLY B . n 
A 1 70  VAL 70  70  70  VAL VAL B . n 
A 1 71  ASN 71  71  71  ASN ASN B . n 
A 1 72  LEU 72  72  72  LEU LEU B . n 
A 1 73  THR 73  73  73  THR THR B . n 
A 1 74  SER 74  74  74  SER SER B . n 
A 1 75  MET 75  75  75  MET MET B . n 
A 1 76  SER 76  76  76  SER SER B . n 
A 1 77  LYS 77  77  77  LYS LYS B . n 
A 1 78  ILE 78  78  78  ILE ILE B . n 
A 1 79  LEU 79  79  79  LEU LEU B . n 
A 1 80  LYS 80  80  80  LYS LYS B . n 
A 1 81  CYS 81  81  81  CYS CYS B . n 
A 1 82  ALA 82  82  82  ALA ALA B . n 
A 1 83  GLY 83  83  83  GLY GLY B . n 
A 1 84  ASN 84  84  84  ASN ASN B . n 
A 1 85  GLU 85  85  85  GLU GLU B . n 
A 1 86  ASP 86  86  86  ASP ASP B . n 
A 1 87  ILE 87  87  87  ILE ILE B . n 
A 1 88  ILE 88  88  88  ILE ILE B . n 
A 1 89  THR 89  89  89  THR THR B . n 
A 1 90  LEU 90  90  90  LEU LEU B . n 
A 1 91  ARG 91  91  91  ARG ARG B . n 
A 1 92  ALA 92  92  92  ALA ALA B . n 
A 1 93  GLU 93  93  93  GLU GLU B . n 
A 1 94  ASP 94  94  94  ASP ASP B . n 
A 1 95  ASN 95  95  95  ASN ASN B . n 
A 1 96  ALA 96  96  96  ALA ALA B . n 
A 1 97  ASP 97  97  97  ASP ASP B . n 
A 1 98  THR 98  98  98  THR THR B . n 
A 1 99  LEU 99  99  99  LEU LEU B . n 
A 1 100 ALA 100 100 100 ALA ALA B . n 
A 1 101 LEU 101 101 101 LEU LEU B . n 
A 1 102 VAL 102 102 102 VAL VAL B . n 
A 1 103 PHE 103 103 103 PHE PHE B . n 
A 1 104 GLU 104 104 104 GLU GLU B . n 
A 1 105 ALA 105 105 105 ALA ALA B . n 
A 1 106 PRO 106 106 106 PRO PRO B . n 
A 1 107 ASN 107 107 107 ASN ASN B . n 
A 1 108 GLN 108 108 108 GLN GLN B . n 
A 1 109 GLU 109 109 109 GLU GLU B . n 
A 1 110 LYS 110 110 110 LYS LYS B . n 
A 1 111 VAL 111 111 111 VAL VAL B . n 
A 1 112 SER 112 112 112 SER SER B . n 
A 1 113 ASP 113 113 113 ASP ASP B . n 
A 1 114 TYR 114 114 114 TYR TYR B . n 
A 1 115 GLU 115 115 115 GLU GLU B . n 
A 1 116 MET 116 116 116 MET MET B . n 
A 1 117 LYS 117 117 117 LYS LYS B . n 
A 1 118 LEU 118 118 118 LEU LEU B . n 
A 1 119 MET 119 119 119 MET MET B . n 
A 1 120 ASP 120 120 120 ASP ASP B . n 
A 1 121 LEU 121 121 121 LEU LEU B . n 
A 1 122 ASP 122 122 122 ASP ASP B . n 
A 1 123 VAL 123 123 123 VAL VAL B . n 
A 1 124 GLU 124 124 124 GLU GLU B . n 
A 1 125 GLN 125 125 125 GLN GLN B . n 
A 1 126 LEU 126 126 126 LEU LEU B . n 
A 1 127 GLY 127 127 127 GLY GLY B . n 
A 1 128 ILE 128 128 128 ILE ILE B . n 
A 1 129 PRO 129 129 129 PRO PRO B . n 
A 1 130 GLU 130 130 130 GLU GLU B . n 
A 1 131 GLN 131 131 131 GLN GLN B . n 
A 1 132 GLU 132 132 132 GLU GLU B . n 
A 1 133 TYR 133 133 133 TYR TYR B . n 
A 1 134 SER 134 134 134 SER SER B . n 
A 1 135 CYS 135 135 135 CYS CYS B . n 
A 1 136 VAL 136 136 136 VAL VAL B . n 
A 1 137 VAL 137 137 137 VAL VAL B . n 
A 1 138 LYS 138 138 138 LYS LYS B . n 
A 1 139 MET 139 139 139 MET MET B . n 
A 1 140 PRO 140 140 140 PRO PRO B . n 
A 1 141 SER 141 141 141 SER SER B . n 
A 1 142 GLY 142 142 142 GLY GLY B . n 
A 1 143 GLU 143 143 143 GLU GLU B . n 
A 1 144 PHE 144 144 144 PHE PHE B . n 
A 1 145 ALA 145 145 145 ALA ALA B . n 
A 1 146 ARG 146 146 146 ARG ARG B . n 
A 1 147 ILE 147 147 147 ILE ILE B . n 
A 1 148 CYS 148 148 148 CYS CYS B . n 
A 1 149 ARG 149 149 149 ARG ARG B . n 
A 1 150 ASP 150 150 150 ASP ASP B . n 
A 1 151 LEU 151 151 151 LEU LEU B . n 
A 1 152 SER 152 152 152 SER SER B . n 
A 1 153 HIS 153 153 153 HIS HIS B . n 
A 1 154 ILE 154 154 154 ILE ILE B . n 
A 1 155 GLY 155 155 155 GLY GLY B . n 
A 1 156 ASP 156 156 156 ASP ASP B . n 
A 1 157 ALA 157 157 157 ALA ALA B . n 
A 1 158 VAL 158 158 158 VAL VAL B . n 
A 1 159 VAL 159 159 159 VAL VAL B . n 
A 1 160 ILE 160 160 160 ILE ILE B . n 
A 1 161 SER 161 161 161 SER SER B . n 
A 1 162 CYS 162 162 162 CYS CYS B . n 
A 1 163 ALA 163 163 163 ALA ALA B . n 
A 1 164 LYS 164 164 164 LYS LYS B . n 
A 1 165 ASP 165 165 165 ASP ASP B . n 
A 1 166 GLY 166 166 166 GLY GLY B . n 
A 1 167 VAL 167 167 167 VAL VAL B . n 
A 1 168 LYS 168 168 168 LYS LYS B . n 
A 1 169 PHE 169 169 169 PHE PHE B . n 
A 1 170 SER 170 170 170 SER SER B . n 
A 1 171 ALA 171 171 171 ALA ALA B . n 
A 1 172 SER 172 172 172 SER SER B . n 
A 1 173 GLY 173 173 173 GLY GLY B . n 
A 1 174 GLU 174 174 174 GLU GLU B . n 
A 1 175 LEU 175 175 175 LEU LEU B . n 
A 1 176 GLY 176 176 176 GLY GLY B . n 
A 1 177 ASN 177 177 177 ASN ASN B . n 
A 1 178 GLY 178 178 178 GLY GLY B . n 
A 1 179 ASN 179 179 179 ASN ASN B . n 
A 1 180 ILE 180 180 180 ILE ILE B . n 
A 1 181 LYS 181 181 181 LYS LYS B . n 
A 1 182 LEU 182 182 182 LEU LEU B . n 
A 1 183 SER 183 183 183 SER SER B . n 
A 1 184 GLN 184 184 184 GLN GLN B . n 
A 1 185 THR 185 185 185 THR THR B . n 
A 1 186 SER 186 186 186 SER SER B . n 
A 1 187 ASN 187 187 187 ASN ASN B . n 
A 1 188 VAL 188 188 188 VAL VAL B . n 
A 1 189 ASP 189 189 189 ASP ASP B . n 
A 1 190 LYS 190 190 190 LYS LYS B . n 
A 1 191 GLU 191 191 191 GLU GLU B . n 
A 1 192 GLU 192 192 192 GLU GLU B . n 
A 1 193 GLU 193 193 193 GLU GLU B . n 
A 1 194 ALA 194 194 194 ALA ALA B . n 
A 1 195 VAL 195 195 195 VAL VAL B . n 
A 1 196 THR 196 196 196 THR THR B . n 
A 1 197 ILE 197 197 197 ILE ILE B . n 
A 1 198 GLU 198 198 198 GLU GLU B . n 
A 1 199 MET 199 199 199 MET MET B . n 
A 1 200 ASN 200 200 200 ASN ASN B . n 
A 1 201 GLU 201 201 201 GLU GLU B . n 
A 1 202 PRO 202 202 202 PRO PRO B . n 
A 1 203 VAL 203 203 203 VAL VAL B . n 
A 1 204 GLN 204 204 204 GLN GLN B . n 
A 1 205 LEU 205 205 205 LEU LEU B . n 
A 1 206 THR 206 206 206 THR THR B . n 
A 1 207 PHE 207 207 207 PHE PHE B . n 
A 1 208 ALA 208 208 208 ALA ALA B . n 
A 1 209 LEU 209 209 209 LEU LEU B . n 
A 1 210 ARG 210 210 210 ARG ARG B . n 
A 1 211 TYR 211 211 211 TYR TYR B . n 
A 1 212 LEU 212 212 212 LEU LEU B . n 
A 1 213 ASN 213 213 213 ASN ASN B . n 
A 1 214 PHE 214 214 214 PHE PHE B . n 
A 1 215 PHE 215 215 215 PHE PHE B . n 
A 1 216 THR 216 216 216 THR THR B . n 
A 1 217 LYS 217 217 217 LYS LYS B . n 
A 1 218 ALA 218 218 218 ALA ALA B . n 
A 1 219 THR 219 219 219 THR THR B . n 
A 1 220 PRO 220 220 220 PRO PRO B . n 
A 1 221 LEU 221 221 221 LEU LEU B . n 
A 1 222 SER 222 222 222 SER SER B . n 
A 1 223 SER 223 223 223 SER SER B . n 
A 1 224 THR 224 224 224 THR THR B . n 
A 1 225 VAL 225 225 225 VAL VAL B . n 
A 1 226 THR 226 226 226 THR THR B . n 
A 1 227 LEU 227 227 227 LEU LEU B . n 
A 1 228 SER 228 228 228 SER SER B . n 
A 1 229 MET 229 229 229 MET MET B . n 
A 1 230 SER 230 230 230 SER SER B . n 
A 1 231 ALA 231 231 231 ALA ALA B . n 
A 1 232 ASP 232 232 232 ASP ASP B . n 
A 1 233 VAL 233 233 233 VAL VAL B . n 
A 1 234 PRO 234 234 234 PRO PRO B . n 
A 1 235 LEU 235 235 235 LEU LEU B . n 
A 1 236 VAL 236 236 236 VAL VAL B . n 
A 1 237 VAL 237 237 237 VAL VAL B . n 
A 1 238 GLU 238 238 238 GLU GLU B . n 
A 1 239 TYR 239 239 239 TYR TYR B . n 
A 1 240 LYS 240 240 240 LYS LYS B . n 
A 1 241 ILE 241 241 241 ILE ILE B . n 
A 1 242 ALA 242 242 242 ALA ALA B . n 
A 1 243 ASP 243 243 243 ASP ASP B . n 
A 1 244 MET 244 244 244 MET MET B . n 
A 1 245 GLY 245 245 245 GLY GLY B . n 
A 1 246 HIS 246 246 246 HIS HIS B . n 
A 1 247 LEU 247 247 247 LEU LEU B . n 
A 1 248 LYS 248 248 248 LYS LYS B . n 
A 1 249 TYR 249 249 249 TYR TYR B . n 
A 1 250 TYR 250 250 250 TYR TYR B . n 
A 1 251 LEU 251 251 251 LEU LEU B . n 
A 1 252 ALA 252 252 252 ALA ALA B . n 
A 1 253 PRO 253 253 253 PRO PRO B . n 
A 1 254 LYS 254 254 254 LYS LYS B . n 
A 1 255 ILE 255 255 255 ILE ILE B . n 
A 1 256 GLU 256 256 256 GLU GLU B . n 
A 1 257 ASP 257 257 257 ASP ASP B . n 
A 1 258 GLU 258 258 258 GLU GLU B . n 
A 1 259 GLU 259 259 259 GLU GLU B . n 
A 1 260 GLY 260 260 260 GLY GLY B . n 
A 1 261 SER 261 261 261 SER SER B . n 
B 1 1   MET 1   1   1   MET MET C . n 
B 1 2   PHE 2   2   2   PHE PHE C . n 
B 1 3   GLU 3   3   3   GLU GLU C . n 
B 1 4   ALA 4   4   4   ALA ALA C . n 
B 1 5   ARG 5   5   5   ARG ARG C . n 
B 1 6   LEU 6   6   6   LEU LEU C . n 
B 1 7   VAL 7   7   7   VAL VAL C . n 
B 1 8   GLN 8   8   8   GLN GLN C . n 
B 1 9   GLY 9   9   9   GLY GLY C . n 
B 1 10  SER 10  10  10  SER SER C . n 
B 1 11  ILE 11  11  11  ILE ILE C . n 
B 1 12  LEU 12  12  12  LEU LEU C . n 
B 1 13  LYS 13  13  13  LYS LYS C . n 
B 1 14  LYS 14  14  14  LYS LYS C . n 
B 1 15  VAL 15  15  15  VAL VAL C . n 
B 1 16  LEU 16  16  16  LEU LEU C . n 
B 1 17  GLU 17  17  17  GLU GLU C . n 
B 1 18  ALA 18  18  18  ALA ALA C . n 
B 1 19  LEU 19  19  19  LEU LEU C . n 
B 1 20  LYS 20  20  20  LYS LYS C . n 
B 1 21  ASP 21  21  21  ASP ASP C . n 
B 1 22  LEU 22  22  22  LEU LEU C . n 
B 1 23  ILE 23  23  23  ILE ILE C . n 
B 1 24  ASN 24  24  24  ASN ASN C . n 
B 1 25  GLU 25  25  25  GLU GLU C . n 
B 1 26  ALA 26  26  26  ALA ALA C . n 
B 1 27  CYS 27  27  27  CYS CYS C . n 
B 1 28  TRP 28  28  28  TRP TRP C . n 
B 1 29  ASP 29  29  29  ASP ASP C . n 
B 1 30  ILE 30  30  30  ILE ILE C . n 
B 1 31  SER 31  31  31  SER SER C . n 
B 1 32  SER 32  32  32  SER SER C . n 
B 1 33  SER 33  33  33  SER SER C . n 
B 1 34  GLY 34  34  34  GLY GLY C . n 
B 1 35  VAL 35  35  35  VAL VAL C . n 
B 1 36  ASN 36  36  36  ASN ASN C . n 
B 1 37  LEU 37  37  37  LEU LEU C . n 
B 1 38  GLN 38  38  38  GLN GLN C . n 
B 1 39  SER 39  39  39  SER SER C . n 
B 1 40  MET 40  40  40  MET MET C . n 
B 1 41  ASP 41  41  41  ASP ASP C . n 
B 1 42  SER 42  42  42  SER SER C . n 
B 1 43  SER 43  43  43  SER SER C . n 
B 1 44  HIS 44  44  44  HIS HIS C . n 
B 1 45  VAL 45  45  45  VAL VAL C . n 
B 1 46  SER 46  46  46  SER SER C . n 
B 1 47  LEU 47  47  47  LEU LEU C . n 
B 1 48  VAL 48  48  48  VAL VAL C . n 
B 1 49  GLN 49  49  49  GLN GLN C . n 
B 1 50  LEU 50  50  50  LEU LEU C . n 
B 1 51  THR 51  51  51  THR THR C . n 
B 1 52  LEU 52  52  52  LEU LEU C . n 
B 1 53  ARG 53  53  53  ARG ARG C . n 
B 1 54  SER 54  54  54  SER SER C . n 
B 1 55  GLU 55  55  55  GLU GLU C . n 
B 1 56  GLY 56  56  56  GLY GLY C . n 
B 1 57  PHE 57  57  57  PHE PHE C . n 
B 1 58  ASP 58  58  58  ASP ASP C . n 
B 1 59  THR 59  59  59  THR THR C . n 
B 1 60  TYR 60  60  60  TYR TYR C . n 
B 1 61  ARG 61  61  61  ARG ARG C . n 
B 1 62  CYS 62  62  62  CYS CYS C . n 
B 1 63  ASP 63  63  63  ASP ASP C . n 
B 1 64  ARG 64  64  64  ARG ARG C . n 
B 1 65  ASN 65  65  65  ASN ASN C . n 
B 1 66  LEU 66  66  66  LEU LEU C . n 
B 1 67  ALA 67  67  67  ALA ALA C . n 
B 1 68  MET 68  68  68  MET MET C . n 
B 1 69  GLY 69  69  69  GLY GLY C . n 
B 1 70  VAL 70  70  70  VAL VAL C . n 
B 1 71  ASN 71  71  71  ASN ASN C . n 
B 1 72  LEU 72  72  72  LEU LEU C . n 
B 1 73  THR 73  73  73  THR THR C . n 
B 1 74  SER 74  74  74  SER SER C . n 
B 1 75  MET 75  75  75  MET MET C . n 
B 1 76  SER 76  76  76  SER SER C . n 
B 1 77  LYS 77  77  77  LYS LYS C . n 
B 1 78  ILE 78  78  78  ILE ILE C . n 
B 1 79  LEU 79  79  79  LEU LEU C . n 
B 1 80  LYS 80  80  80  LYS LYS C . n 
B 1 81  CYS 81  81  81  CYS CYS C . n 
B 1 82  ALA 82  82  82  ALA ALA C . n 
B 1 83  GLY 83  83  83  GLY GLY C . n 
B 1 84  ASN 84  84  84  ASN ASN C . n 
B 1 85  GLU 85  85  85  GLU GLU C . n 
B 1 86  ASP 86  86  86  ASP ASP C . n 
B 1 87  ILE 87  87  87  ILE ILE C . n 
B 1 88  ILE 88  88  88  ILE ILE C . n 
B 1 89  THR 89  89  89  THR THR C . n 
B 1 90  LEU 90  90  90  LEU LEU C . n 
B 1 91  ARG 91  91  91  ARG ARG C . n 
B 1 92  ALA 92  92  92  ALA ALA C . n 
B 1 93  GLU 93  93  93  GLU GLU C . n 
B 1 94  ASP 94  94  94  ASP ASP C . n 
B 1 95  ASN 95  95  95  ASN ASN C . n 
B 1 96  ALA 96  96  96  ALA ALA C . n 
B 1 97  ASP 97  97  97  ASP ASP C . n 
B 1 98  THR 98  98  98  THR THR C . n 
B 1 99  LEU 99  99  99  LEU LEU C . n 
B 1 100 ALA 100 100 100 ALA ALA C . n 
B 1 101 LEU 101 101 101 LEU LEU C . n 
B 1 102 VAL 102 102 102 VAL VAL C . n 
B 1 103 PHE 103 103 103 PHE PHE C . n 
B 1 104 GLU 104 104 104 GLU GLU C . n 
B 1 105 ALA 105 105 105 ALA ALA C . n 
B 1 106 PRO 106 106 106 PRO PRO C . n 
B 1 107 ASN 107 107 107 ASN ASN C . n 
B 1 108 GLN 108 108 108 GLN GLN C . n 
B 1 109 GLU 109 109 109 GLU GLU C . n 
B 1 110 LYS 110 110 110 LYS LYS C . n 
B 1 111 VAL 111 111 111 VAL VAL C . n 
B 1 112 SER 112 112 112 SER SER C . n 
B 1 113 ASP 113 113 113 ASP ASP C . n 
B 1 114 TYR 114 114 114 TYR TYR C . n 
B 1 115 GLU 115 115 115 GLU GLU C . n 
B 1 116 MET 116 116 116 MET MET C . n 
B 1 117 LYS 117 117 117 LYS LYS C . n 
B 1 118 LEU 118 118 118 LEU LEU C . n 
B 1 119 MET 119 119 119 MET MET C . n 
B 1 120 ASP 120 120 120 ASP ASP C . n 
B 1 121 LEU 121 121 121 LEU LEU C . n 
B 1 122 ASP 122 122 122 ASP ASP C . n 
B 1 123 VAL 123 123 123 VAL VAL C . n 
B 1 124 GLU 124 124 124 GLU GLU C . n 
B 1 125 GLN 125 125 125 GLN GLN C . n 
B 1 126 LEU 126 126 126 LEU LEU C . n 
B 1 127 GLY 127 127 127 GLY GLY C . n 
B 1 128 ILE 128 128 128 ILE ILE C . n 
B 1 129 PRO 129 129 129 PRO PRO C . n 
B 1 130 GLU 130 130 130 GLU GLU C . n 
B 1 131 GLN 131 131 131 GLN GLN C . n 
B 1 132 GLU 132 132 132 GLU GLU C . n 
B 1 133 TYR 133 133 133 TYR TYR C . n 
B 1 134 SER 134 134 134 SER SER C . n 
B 1 135 CYS 135 135 135 CYS CYS C . n 
B 1 136 VAL 136 136 136 VAL VAL C . n 
B 1 137 VAL 137 137 137 VAL VAL C . n 
B 1 138 LYS 138 138 138 LYS LYS C . n 
B 1 139 MET 139 139 139 MET MET C . n 
B 1 140 PRO 140 140 140 PRO PRO C . n 
B 1 141 SER 141 141 141 SER SER C . n 
B 1 142 GLY 142 142 142 GLY GLY C . n 
B 1 143 GLU 143 143 143 GLU GLU C . n 
B 1 144 PHE 144 144 144 PHE PHE C . n 
B 1 145 ALA 145 145 145 ALA ALA C . n 
B 1 146 ARG 146 146 146 ARG ARG C . n 
B 1 147 ILE 147 147 147 ILE ILE C . n 
B 1 148 CYS 148 148 148 CYS CYS C . n 
B 1 149 ARG 149 149 149 ARG ARG C . n 
B 1 150 ASP 150 150 150 ASP ASP C . n 
B 1 151 LEU 151 151 151 LEU LEU C . n 
B 1 152 SER 152 152 152 SER SER C . n 
B 1 153 HIS 153 153 153 HIS HIS C . n 
B 1 154 ILE 154 154 154 ILE ILE C . n 
B 1 155 GLY 155 155 155 GLY GLY C . n 
B 1 156 ASP 156 156 156 ASP ASP C . n 
B 1 157 ALA 157 157 157 ALA ALA C . n 
B 1 158 VAL 158 158 158 VAL VAL C . n 
B 1 159 VAL 159 159 159 VAL VAL C . n 
B 1 160 ILE 160 160 160 ILE ILE C . n 
B 1 161 SER 161 161 161 SER SER C . n 
B 1 162 CYS 162 162 162 CYS CYS C . n 
B 1 163 ALA 163 163 163 ALA ALA C . n 
B 1 164 LYS 164 164 164 LYS LYS C . n 
B 1 165 ASP 165 165 165 ASP ASP C . n 
B 1 166 GLY 166 166 166 GLY GLY C . n 
B 1 167 VAL 167 167 167 VAL VAL C . n 
B 1 168 LYS 168 168 168 LYS LYS C . n 
B 1 169 PHE 169 169 169 PHE PHE C . n 
B 1 170 SER 170 170 170 SER SER C . n 
B 1 171 ALA 171 171 171 ALA ALA C . n 
B 1 172 SER 172 172 172 SER SER C . n 
B 1 173 GLY 173 173 173 GLY GLY C . n 
B 1 174 GLU 174 174 174 GLU GLU C . n 
B 1 175 LEU 175 175 175 LEU LEU C . n 
B 1 176 GLY 176 176 176 GLY GLY C . n 
B 1 177 ASN 177 177 177 ASN ASN C . n 
B 1 178 GLY 178 178 178 GLY GLY C . n 
B 1 179 ASN 179 179 179 ASN ASN C . n 
B 1 180 ILE 180 180 180 ILE ILE C . n 
B 1 181 LYS 181 181 181 LYS LYS C . n 
B 1 182 LEU 182 182 182 LEU LEU C . n 
B 1 183 SER 183 183 183 SER SER C . n 
B 1 184 GLN 184 184 184 GLN GLN C . n 
B 1 185 THR 185 185 185 THR THR C . n 
B 1 186 SER 186 186 186 SER SER C . n 
B 1 187 ASN 187 187 187 ASN ASN C . n 
B 1 188 VAL 188 188 188 VAL VAL C . n 
B 1 189 ASP 189 189 189 ASP ASP C . n 
B 1 190 LYS 190 190 190 LYS LYS C . n 
B 1 191 GLU 191 191 191 GLU GLU C . n 
B 1 192 GLU 192 192 192 GLU GLU C . n 
B 1 193 GLU 193 193 193 GLU GLU C . n 
B 1 194 ALA 194 194 194 ALA ALA C . n 
B 1 195 VAL 195 195 195 VAL VAL C . n 
B 1 196 THR 196 196 196 THR THR C . n 
B 1 197 ILE 197 197 197 ILE ILE C . n 
B 1 198 GLU 198 198 198 GLU GLU C . n 
B 1 199 MET 199 199 199 MET MET C . n 
B 1 200 ASN 200 200 200 ASN ASN C . n 
B 1 201 GLU 201 201 201 GLU GLU C . n 
B 1 202 PRO 202 202 202 PRO PRO C . n 
B 1 203 VAL 203 203 203 VAL VAL C . n 
B 1 204 GLN 204 204 204 GLN GLN C . n 
B 1 205 LEU 205 205 205 LEU LEU C . n 
B 1 206 THR 206 206 206 THR THR C . n 
B 1 207 PHE 207 207 207 PHE PHE C . n 
B 1 208 ALA 208 208 208 ALA ALA C . n 
B 1 209 LEU 209 209 209 LEU LEU C . n 
B 1 210 ARG 210 210 210 ARG ARG C . n 
B 1 211 TYR 211 211 211 TYR TYR C . n 
B 1 212 LEU 212 212 212 LEU LEU C . n 
B 1 213 ASN 213 213 213 ASN ASN C . n 
B 1 214 PHE 214 214 214 PHE PHE C . n 
B 1 215 PHE 215 215 215 PHE PHE C . n 
B 1 216 THR 216 216 216 THR THR C . n 
B 1 217 LYS 217 217 217 LYS LYS C . n 
B 1 218 ALA 218 218 218 ALA ALA C . n 
B 1 219 THR 219 219 219 THR THR C . n 
B 1 220 PRO 220 220 220 PRO PRO C . n 
B 1 221 LEU 221 221 221 LEU LEU C . n 
B 1 222 SER 222 222 222 SER SER C . n 
B 1 223 SER 223 223 223 SER SER C . n 
B 1 224 THR 224 224 224 THR THR C . n 
B 1 225 VAL 225 225 225 VAL VAL C . n 
B 1 226 THR 226 226 226 THR THR C . n 
B 1 227 LEU 227 227 227 LEU LEU C . n 
B 1 228 SER 228 228 228 SER SER C . n 
B 1 229 MET 229 229 229 MET MET C . n 
B 1 230 SER 230 230 230 SER SER C . n 
B 1 231 ALA 231 231 231 ALA ALA C . n 
B 1 232 ASP 232 232 232 ASP ASP C . n 
B 1 233 VAL 233 233 233 VAL VAL C . n 
B 1 234 PRO 234 234 234 PRO PRO C . n 
B 1 235 LEU 235 235 235 LEU LEU C . n 
B 1 236 VAL 236 236 236 VAL VAL C . n 
B 1 237 VAL 237 237 237 VAL VAL C . n 
B 1 238 GLU 238 238 238 GLU GLU C . n 
B 1 239 TYR 239 239 239 TYR TYR C . n 
B 1 240 LYS 240 240 240 LYS LYS C . n 
B 1 241 ILE 241 241 241 ILE ILE C . n 
B 1 242 ALA 242 242 242 ALA ALA C . n 
B 1 243 ASP 243 243 243 ASP ASP C . n 
B 1 244 MET 244 244 244 MET MET C . n 
B 1 245 GLY 245 245 245 GLY GLY C . n 
B 1 246 HIS 246 246 246 HIS HIS C . n 
B 1 247 LEU 247 247 247 LEU LEU C . n 
B 1 248 LYS 248 248 248 LYS LYS C . n 
B 1 249 TYR 249 249 249 TYR TYR C . n 
B 1 250 TYR 250 250 250 TYR TYR C . n 
B 1 251 LEU 251 251 251 LEU LEU C . n 
B 1 252 ALA 252 252 252 ALA ALA C . n 
B 1 253 PRO 253 253 253 PRO PRO C . n 
B 1 254 LYS 254 254 254 LYS LYS C . n 
B 1 255 ILE 255 255 255 ILE ILE C . n 
B 1 256 GLU 256 256 256 GLU GLU C . n 
B 1 257 ASP 257 257 257 ASP ASP C . n 
B 1 258 GLU 258 258 258 GLU GLU C . n 
B 1 259 GLU 259 259 259 GLU GLU C . n 
B 1 260 GLY 260 260 260 GLY GLY C . n 
B 1 261 SER 261 261 261 SER SER C . n 
C 1 1   MET 1   1   1   MET MET D . n 
C 1 2   PHE 2   2   2   PHE PHE D . n 
C 1 3   GLU 3   3   3   GLU GLU D . n 
C 1 4   ALA 4   4   4   ALA ALA D . n 
C 1 5   ARG 5   5   5   ARG ARG D . n 
C 1 6   LEU 6   6   6   LEU LEU D . n 
C 1 7   VAL 7   7   7   VAL VAL D . n 
C 1 8   GLN 8   8   8   GLN GLN D . n 
C 1 9   GLY 9   9   9   GLY GLY D . n 
C 1 10  SER 10  10  10  SER SER D . n 
C 1 11  ILE 11  11  11  ILE ILE D . n 
C 1 12  LEU 12  12  12  LEU LEU D . n 
C 1 13  LYS 13  13  13  LYS LYS D . n 
C 1 14  LYS 14  14  14  LYS LYS D . n 
C 1 15  VAL 15  15  15  VAL VAL D . n 
C 1 16  LEU 16  16  16  LEU LEU D . n 
C 1 17  GLU 17  17  17  GLU GLU D . n 
C 1 18  ALA 18  18  18  ALA ALA D . n 
C 1 19  LEU 19  19  19  LEU LEU D . n 
C 1 20  LYS 20  20  20  LYS LYS D . n 
C 1 21  ASP 21  21  21  ASP ASP D . n 
C 1 22  LEU 22  22  22  LEU LEU D . n 
C 1 23  ILE 23  23  23  ILE ILE D . n 
C 1 24  ASN 24  24  24  ASN ASN D . n 
C 1 25  GLU 25  25  25  GLU GLU D . n 
C 1 26  ALA 26  26  26  ALA ALA D . n 
C 1 27  CYS 27  27  27  CYS CYS D . n 
C 1 28  TRP 28  28  28  TRP TRP D . n 
C 1 29  ASP 29  29  29  ASP ASP D . n 
C 1 30  ILE 30  30  30  ILE ILE D . n 
C 1 31  SER 31  31  31  SER SER D . n 
C 1 32  SER 32  32  32  SER SER D . n 
C 1 33  SER 33  33  33  SER SER D . n 
C 1 34  GLY 34  34  34  GLY GLY D . n 
C 1 35  VAL 35  35  35  VAL VAL D . n 
C 1 36  ASN 36  36  36  ASN ASN D . n 
C 1 37  LEU 37  37  37  LEU LEU D . n 
C 1 38  GLN 38  38  38  GLN GLN D . n 
C 1 39  SER 39  39  39  SER SER D . n 
C 1 40  MET 40  40  40  MET MET D . n 
C 1 41  ASP 41  41  41  ASP ASP D . n 
C 1 42  SER 42  42  42  SER SER D . n 
C 1 43  SER 43  43  43  SER SER D . n 
C 1 44  HIS 44  44  44  HIS HIS D . n 
C 1 45  VAL 45  45  45  VAL VAL D . n 
C 1 46  SER 46  46  46  SER SER D . n 
C 1 47  LEU 47  47  47  LEU LEU D . n 
C 1 48  VAL 48  48  48  VAL VAL D . n 
C 1 49  GLN 49  49  49  GLN GLN D . n 
C 1 50  LEU 50  50  50  LEU LEU D . n 
C 1 51  THR 51  51  51  THR THR D . n 
C 1 52  LEU 52  52  52  LEU LEU D . n 
C 1 53  ARG 53  53  53  ARG ARG D . n 
C 1 54  SER 54  54  54  SER SER D . n 
C 1 55  GLU 55  55  55  GLU GLU D . n 
C 1 56  GLY 56  56  56  GLY GLY D . n 
C 1 57  PHE 57  57  57  PHE PHE D . n 
C 1 58  ASP 58  58  58  ASP ASP D . n 
C 1 59  THR 59  59  59  THR THR D . n 
C 1 60  TYR 60  60  60  TYR TYR D . n 
C 1 61  ARG 61  61  61  ARG ARG D . n 
C 1 62  CYS 62  62  62  CYS CYS D . n 
C 1 63  ASP 63  63  63  ASP ASP D . n 
C 1 64  ARG 64  64  64  ARG ARG D . n 
C 1 65  ASN 65  65  65  ASN ASN D . n 
C 1 66  LEU 66  66  66  LEU LEU D . n 
C 1 67  ALA 67  67  67  ALA ALA D . n 
C 1 68  MET 68  68  68  MET MET D . n 
C 1 69  GLY 69  69  69  GLY GLY D . n 
C 1 70  VAL 70  70  70  VAL VAL D . n 
C 1 71  ASN 71  71  71  ASN ASN D . n 
C 1 72  LEU 72  72  72  LEU LEU D . n 
C 1 73  THR 73  73  73  THR THR D . n 
C 1 74  SER 74  74  74  SER SER D . n 
C 1 75  MET 75  75  75  MET MET D . n 
C 1 76  SER 76  76  76  SER SER D . n 
C 1 77  LYS 77  77  77  LYS LYS D . n 
C 1 78  ILE 78  78  78  ILE ILE D . n 
C 1 79  LEU 79  79  79  LEU LEU D . n 
C 1 80  LYS 80  80  80  LYS LYS D . n 
C 1 81  CYS 81  81  81  CYS CYS D . n 
C 1 82  ALA 82  82  82  ALA ALA D . n 
C 1 83  GLY 83  83  83  GLY GLY D . n 
C 1 84  ASN 84  84  84  ASN ASN D . n 
C 1 85  GLU 85  85  85  GLU GLU D . n 
C 1 86  ASP 86  86  86  ASP ASP D . n 
C 1 87  ILE 87  87  87  ILE ILE D . n 
C 1 88  ILE 88  88  88  ILE ILE D . n 
C 1 89  THR 89  89  89  THR THR D . n 
C 1 90  LEU 90  90  90  LEU LEU D . n 
C 1 91  ARG 91  91  91  ARG ARG D . n 
C 1 92  ALA 92  92  92  ALA ALA D . n 
C 1 93  GLU 93  93  93  GLU GLU D . n 
C 1 94  ASP 94  94  94  ASP ASP D . n 
C 1 95  ASN 95  95  95  ASN ASN D . n 
C 1 96  ALA 96  96  96  ALA ALA D . n 
C 1 97  ASP 97  97  97  ASP ASP D . n 
C 1 98  THR 98  98  98  THR THR D . n 
C 1 99  LEU 99  99  99  LEU LEU D . n 
C 1 100 ALA 100 100 100 ALA ALA D . n 
C 1 101 LEU 101 101 101 LEU LEU D . n 
C 1 102 VAL 102 102 102 VAL VAL D . n 
C 1 103 PHE 103 103 103 PHE PHE D . n 
C 1 104 GLU 104 104 104 GLU GLU D . n 
C 1 105 ALA 105 105 105 ALA ALA D . n 
C 1 106 PRO 106 106 106 PRO PRO D . n 
C 1 107 ASN 107 107 107 ASN ASN D . n 
C 1 108 GLN 108 108 108 GLN GLN D . n 
C 1 109 GLU 109 109 109 GLU GLU D . n 
C 1 110 LYS 110 110 110 LYS LYS D . n 
C 1 111 VAL 111 111 111 VAL VAL D . n 
C 1 112 SER 112 112 112 SER SER D . n 
C 1 113 ASP 113 113 113 ASP ASP D . n 
C 1 114 TYR 114 114 114 TYR TYR D . n 
C 1 115 GLU 115 115 115 GLU GLU D . n 
C 1 116 MET 116 116 116 MET MET D . n 
C 1 117 LYS 117 117 117 LYS LYS D . n 
C 1 118 LEU 118 118 118 LEU LEU D . n 
C 1 119 MET 119 119 119 MET MET D . n 
C 1 120 ASP 120 120 120 ASP ASP D . n 
C 1 121 LEU 121 121 121 LEU LEU D . n 
C 1 122 ASP 122 122 122 ASP ASP D . n 
C 1 123 VAL 123 123 123 VAL VAL D . n 
C 1 124 GLU 124 124 124 GLU GLU D . n 
C 1 125 GLN 125 125 125 GLN GLN D . n 
C 1 126 LEU 126 126 126 LEU LEU D . n 
C 1 127 GLY 127 127 127 GLY GLY D . n 
C 1 128 ILE 128 128 128 ILE ILE D . n 
C 1 129 PRO 129 129 129 PRO PRO D . n 
C 1 130 GLU 130 130 130 GLU GLU D . n 
C 1 131 GLN 131 131 131 GLN GLN D . n 
C 1 132 GLU 132 132 132 GLU GLU D . n 
C 1 133 TYR 133 133 133 TYR TYR D . n 
C 1 134 SER 134 134 134 SER SER D . n 
C 1 135 CYS 135 135 135 CYS CYS D . n 
C 1 136 VAL 136 136 136 VAL VAL D . n 
C 1 137 VAL 137 137 137 VAL VAL D . n 
C 1 138 LYS 138 138 138 LYS LYS D . n 
C 1 139 MET 139 139 139 MET MET D . n 
C 1 140 PRO 140 140 140 PRO PRO D . n 
C 1 141 SER 141 141 141 SER SER D . n 
C 1 142 GLY 142 142 142 GLY GLY D . n 
C 1 143 GLU 143 143 143 GLU GLU D . n 
C 1 144 PHE 144 144 144 PHE PHE D . n 
C 1 145 ALA 145 145 145 ALA ALA D . n 
C 1 146 ARG 146 146 146 ARG ARG D . n 
C 1 147 ILE 147 147 147 ILE ILE D . n 
C 1 148 CYS 148 148 148 CYS CYS D . n 
C 1 149 ARG 149 149 149 ARG ARG D . n 
C 1 150 ASP 150 150 150 ASP ASP D . n 
C 1 151 LEU 151 151 151 LEU LEU D . n 
C 1 152 SER 152 152 152 SER SER D . n 
C 1 153 HIS 153 153 153 HIS HIS D . n 
C 1 154 ILE 154 154 154 ILE ILE D . n 
C 1 155 GLY 155 155 155 GLY GLY D . n 
C 1 156 ASP 156 156 156 ASP ASP D . n 
C 1 157 ALA 157 157 157 ALA ALA D . n 
C 1 158 VAL 158 158 158 VAL VAL D . n 
C 1 159 VAL 159 159 159 VAL VAL D . n 
C 1 160 ILE 160 160 160 ILE ILE D . n 
C 1 161 SER 161 161 161 SER SER D . n 
C 1 162 CYS 162 162 162 CYS CYS D . n 
C 1 163 ALA 163 163 163 ALA ALA D . n 
C 1 164 LYS 164 164 164 LYS LYS D . n 
C 1 165 ASP 165 165 165 ASP ASP D . n 
C 1 166 GLY 166 166 166 GLY GLY D . n 
C 1 167 VAL 167 167 167 VAL VAL D . n 
C 1 168 LYS 168 168 168 LYS LYS D . n 
C 1 169 PHE 169 169 169 PHE PHE D . n 
C 1 170 SER 170 170 170 SER SER D . n 
C 1 171 ALA 171 171 171 ALA ALA D . n 
C 1 172 SER 172 172 172 SER SER D . n 
C 1 173 GLY 173 173 173 GLY GLY D . n 
C 1 174 GLU 174 174 174 GLU GLU D . n 
C 1 175 LEU 175 175 175 LEU LEU D . n 
C 1 176 GLY 176 176 176 GLY GLY D . n 
C 1 177 ASN 177 177 177 ASN ASN D . n 
C 1 178 GLY 178 178 178 GLY GLY D . n 
C 1 179 ASN 179 179 179 ASN ASN D . n 
C 1 180 ILE 180 180 180 ILE ILE D . n 
C 1 181 LYS 181 181 181 LYS LYS D . n 
C 1 182 LEU 182 182 182 LEU LEU D . n 
C 1 183 SER 183 183 183 SER SER D . n 
C 1 184 GLN 184 184 184 GLN GLN D . n 
C 1 185 THR 185 185 185 THR THR D . n 
C 1 186 SER 186 186 186 SER SER D . n 
C 1 187 ASN 187 187 187 ASN ASN D . n 
C 1 188 VAL 188 188 188 VAL VAL D . n 
C 1 189 ASP 189 189 189 ASP ASP D . n 
C 1 190 LYS 190 190 190 LYS LYS D . n 
C 1 191 GLU 191 191 191 GLU GLU D . n 
C 1 192 GLU 192 192 192 GLU GLU D . n 
C 1 193 GLU 193 193 193 GLU GLU D . n 
C 1 194 ALA 194 194 194 ALA ALA D . n 
C 1 195 VAL 195 195 195 VAL VAL D . n 
C 1 196 THR 196 196 196 THR THR D . n 
C 1 197 ILE 197 197 197 ILE ILE D . n 
C 1 198 GLU 198 198 198 GLU GLU D . n 
C 1 199 MET 199 199 199 MET MET D . n 
C 1 200 ASN 200 200 200 ASN ASN D . n 
C 1 201 GLU 201 201 201 GLU GLU D . n 
C 1 202 PRO 202 202 202 PRO PRO D . n 
C 1 203 VAL 203 203 203 VAL VAL D . n 
C 1 204 GLN 204 204 204 GLN GLN D . n 
C 1 205 LEU 205 205 205 LEU LEU D . n 
C 1 206 THR 206 206 206 THR THR D . n 
C 1 207 PHE 207 207 207 PHE PHE D . n 
C 1 208 ALA 208 208 208 ALA ALA D . n 
C 1 209 LEU 209 209 209 LEU LEU D . n 
C 1 210 ARG 210 210 210 ARG ARG D . n 
C 1 211 TYR 211 211 211 TYR TYR D . n 
C 1 212 LEU 212 212 212 LEU LEU D . n 
C 1 213 ASN 213 213 213 ASN ASN D . n 
C 1 214 PHE 214 214 214 PHE PHE D . n 
C 1 215 PHE 215 215 215 PHE PHE D . n 
C 1 216 THR 216 216 216 THR THR D . n 
C 1 217 LYS 217 217 217 LYS LYS D . n 
C 1 218 ALA 218 218 218 ALA ALA D . n 
C 1 219 THR 219 219 219 THR THR D . n 
C 1 220 PRO 220 220 220 PRO PRO D . n 
C 1 221 LEU 221 221 221 LEU LEU D . n 
C 1 222 SER 222 222 222 SER SER D . n 
C 1 223 SER 223 223 223 SER SER D . n 
C 1 224 THR 224 224 224 THR THR D . n 
C 1 225 VAL 225 225 225 VAL VAL D . n 
C 1 226 THR 226 226 226 THR THR D . n 
C 1 227 LEU 227 227 227 LEU LEU D . n 
C 1 228 SER 228 228 228 SER SER D . n 
C 1 229 MET 229 229 229 MET MET D . n 
C 1 230 SER 230 230 230 SER SER D . n 
C 1 231 ALA 231 231 231 ALA ALA D . n 
C 1 232 ASP 232 232 232 ASP ASP D . n 
C 1 233 VAL 233 233 233 VAL VAL D . n 
C 1 234 PRO 234 234 234 PRO PRO D . n 
C 1 235 LEU 235 235 235 LEU LEU D . n 
C 1 236 VAL 236 236 236 VAL VAL D . n 
C 1 237 VAL 237 237 237 VAL VAL D . n 
C 1 238 GLU 238 238 238 GLU GLU D . n 
C 1 239 TYR 239 239 239 TYR TYR D . n 
C 1 240 LYS 240 240 240 LYS LYS D . n 
C 1 241 ILE 241 241 241 ILE ILE D . n 
C 1 242 ALA 242 242 242 ALA ALA D . n 
C 1 243 ASP 243 243 243 ASP ASP D . n 
C 1 244 MET 244 244 244 MET MET D . n 
C 1 245 GLY 245 245 245 GLY GLY D . n 
C 1 246 HIS 246 246 246 HIS HIS D . n 
C 1 247 LEU 247 247 247 LEU LEU D . n 
C 1 248 LYS 248 248 248 LYS LYS D . n 
C 1 249 TYR 249 249 249 TYR TYR D . n 
C 1 250 TYR 250 250 250 TYR TYR D . n 
C 1 251 LEU 251 251 251 LEU LEU D . n 
C 1 252 ALA 252 252 252 ALA ALA D . n 
C 1 253 PRO 253 253 253 PRO PRO D . n 
C 1 254 LYS 254 254 254 LYS LYS D . n 
C 1 255 ILE 255 255 255 ILE ILE D . n 
C 1 256 GLU 256 256 256 GLU GLU D . n 
C 1 257 ASP 257 257 257 ASP ASP D . n 
C 1 258 GLU 258 258 258 GLU GLU D . n 
C 1 259 GLU 259 259 259 GLU GLU D . n 
C 1 260 GLY 260 260 260 GLY GLY D . n 
C 1 261 SER 261 261 261 SER SER D . n 
D 2 1   HIS 1   372 372 HIS HIS E . n 
D 2 2   PRO 2   373 373 PRO PRO E . n 
D 2 3   TYR 3   374 374 TYR TYR E . n 
D 2 4   TYR 4   375 375 TYR TYR E . n 
D 2 5   LEU 5   376 376 LEU LEU E . n 
D 2 6   ARG 6   377 377 ARG ARG E . n 
D 2 7   SER 7   378 378 SER SER E . n 
D 2 8   PHE 8   379 379 PHE PHE E . n 
D 2 9   LEU 9   380 380 LEU LEU E . n 
D 2 10  VAL 10  381 381 VAL VAL E . n 
D 2 11  VAL 11  382 382 VAL VAL E . n 
D 2 12  LEU 12  383 383 LEU LEU E . n 
D 2 13  LYS 13  384 384 LYS LYS E . n 
D 2 14  THR 14  385 385 THR THR E . n 
D 2 15  VAL 15  386 386 VAL VAL E . n 
D 2 16  LEU 16  387 387 LEU LEU E . n 
D 2 17  GLU 17  388 388 GLU GLU E . n 
D 2 18  ASN 18  389 389 ASN ASN E . n 
D 2 19  GLU 19  390 390 GLU GLU E . n 
D 2 20  ASP 20  391 391 ASP ASP E . n 
D 2 21  ASP 21  392 392 ASP ASP E . n 
D 2 22  MET 22  393 393 MET MET E . n 
D 2 23  LEU 23  394 394 LEU LEU E . n 
D 2 24  LEU 24  395 395 LEU LEU E . n 
D 2 25  PHE 25  396 396 PHE PHE E . n 
D 2 26  ASP 26  397 397 ASP ASP E . n 
D 2 27  GLU 27  398 398 GLU GLU E . n 
D 2 28  GLN 28  399 399 GLN GLN E . n 
D 2 29  GLU 29  400 400 GLU GLU E . n 
D 2 30  LYS 30  401 401 LYS LYS E . n 
D 2 31  GLY 31  402 402 GLY GLY E . n 
D 2 32  ILE 32  403 403 ILE ILE E . n 
D 2 33  VAL 33  404 404 VAL VAL E . n 
D 2 34  THR 34  405 405 THR THR E . n 
D 2 35  LYS 35  406 406 LYS LYS E . n 
D 2 36  PHE 36  407 407 PHE PHE E . n 
D 2 37  TYR 37  408 408 TYR TYR E . n 
D 2 38  GLN 38  409 409 GLN GLN E . n 
D 2 39  LEU 39  410 410 LEU LEU E . n 
D 2 40  SER 40  411 411 SER SER E . n 
D 2 41  ALA 41  412 412 ALA ALA E . n 
D 2 42  THR 42  413 413 THR THR E . n 
D 2 43  GLY 43  414 414 GLY GLY E . n 
D 2 44  GLN 44  415 415 GLN GLN E . n 
D 2 45  LYS 45  416 416 LYS LYS E . n 
D 2 46  LEU 46  417 417 LEU LEU E . n 
D 2 47  TYR 47  418 418 TYR TYR E . n 
D 2 48  VAL 48  419 419 VAL VAL E . n 
D 2 49  ARG 49  420 420 ARG ARG E . n 
D 2 50  LEU 50  421 421 LEU LEU E . n 
D 2 51  PHE 51  422 422 PHE PHE E . n 
D 2 52  GLN 52  423 423 GLN GLN E . n 
D 2 53  ARG 53  424 424 ARG ARG E . n 
D 2 54  LYS 54  425 425 LYS LYS E . n 
D 2 55  LEU 55  426 426 LEU LEU E . n 
D 2 56  SER 56  427 427 SER SER E . n 
D 2 57  TRP 57  428 428 TRP TRP E . n 
D 2 58  ILE 58  429 429 ILE ILE E . n 
D 2 59  LYS 59  430 430 LYS LYS E . n 
D 2 60  MET 60  431 431 MET MET E . n 
D 2 61  THR 61  432 432 THR THR E . n 
D 2 62  LYS 62  433 433 LYS LYS E . n 
D 2 63  LEU 63  434 434 LEU LEU E . n 
D 2 64  GLU 64  435 435 GLU GLU E . n 
D 2 65  TYR 65  436 436 TYR TYR E . n 
D 2 66  GLU 66  437 437 GLU GLU E . n 
D 2 67  GLU 67  438 438 GLU GLU E . n 
D 2 68  ILE 68  439 439 ILE ILE E . n 
D 2 69  ALA 69  440 440 ALA ALA E . n 
D 2 70  LEU 70  441 441 LEU LEU E . n 
D 2 71  ASP 71  442 442 ASP ASP E . n 
D 2 72  LEU 72  443 443 LEU LEU E . n 
D 2 73  THR 73  444 444 THR THR E . n 
D 2 74  PRO 74  445 445 PRO PRO E . n 
D 2 75  VAL 75  446 446 VAL VAL E . n 
D 2 76  ILE 76  447 447 ILE ILE E . n 
D 2 77  GLU 77  448 448 GLU GLU E . n 
D 2 78  GLU 78  449 449 GLU GLU E . n 
D 2 79  LEU 79  450 450 LEU LEU E . n 
D 2 80  THR 80  451 451 THR THR E . n 
D 2 81  ASN 81  452 452 ASN ASN E . n 
D 2 82  ALA 82  453 453 ALA ALA E . n 
D 2 83  GLY 83  454 454 GLY GLY E . n 
D 2 84  PHE 84  455 455 PHE PHE E . n 
D 2 85  LEU 85  456 456 LEU LEU E . n 
D 2 86  GLN 86  457 457 GLN GLN E . n 
D 2 87  THR 87  458 458 THR THR E . n 
D 2 88  GLU 88  459 459 GLU GLU E . n 
D 2 89  SER 89  460 460 SER SER E . n 
D 2 90  GLU 90  461 461 GLU GLU E . n 
D 2 91  LEU 91  462 462 LEU LEU E . n 
D 2 92  GLN 92  463 463 GLN GLN E . n 
D 2 93  GLU 93  464 464 GLU GLU E . n 
D 2 94  LEU 94  465 465 LEU LEU E . n 
D 2 95  SER 95  466 466 SER SER E . n 
D 2 96  GLU 96  467 467 GLU GLU E . n 
D 2 97  VAL 97  468 468 VAL VAL E . n 
D 2 98  LEU 98  469 469 LEU LEU E . n 
D 2 99  GLU 99  470 470 GLU GLU E . n 
D 2 100 LEU 100 471 471 LEU LEU E . n 
D 2 101 LEU 101 472 472 LEU LEU E . n 
D 2 102 SER 102 473 473 SER SER E . n 
D 2 103 ALA 103 474 474 ALA ALA E . n 
D 2 104 PRO 104 475 475 PRO PRO E . n 
D 2 105 GLU 105 476 476 GLU GLU E . n 
D 2 106 LEU 106 477 477 LEU LEU E . n 
D 2 107 LYS 107 478 478 LYS LYS E . n 
D 2 108 SER 108 479 479 SER SER E . n 
D 2 109 LEU 109 480 480 LEU LEU E . n 
D 2 110 ALA 110 481 481 ALA ALA E . n 
D 2 111 LYS 111 482 482 LYS LYS E . n 
D 2 112 THR 112 483 483 THR THR E . n 
D 2 113 PHE 113 484 484 PHE PHE E . n 
D 2 114 HIS 114 485 485 HIS HIS E . n 
D 2 115 LEU 115 486 486 LEU LEU E . n 
D 2 116 VAL 116 487 487 VAL VAL E . n 
D 2 117 ASN 117 488 488 ASN ASN E . n 
D 2 118 PRO 118 489 489 PRO PRO E . n 
D 2 119 ASN 119 490 490 ASN ASN E . n 
D 2 120 GLY 120 491 491 GLY GLY E . n 
D 2 121 GLN 121 492 492 GLN GLN E . n 
D 2 122 LYS 122 493 493 LYS LYS E . n 
D 2 123 GLN 123 494 494 GLN GLN E . n 
D 2 124 GLN 124 495 495 GLN GLN E . n 
D 2 125 LEU 125 496 496 LEU LEU E . n 
D 2 126 VAL 126 497 497 VAL VAL E . n 
D 2 127 ASP 127 498 498 ASP ASP E . n 
D 2 128 ALA 128 499 499 ALA ALA E . n 
D 2 129 PHE 129 500 500 PHE PHE E . n 
D 2 130 LEU 130 501 501 LEU LEU E . n 
D 2 131 LYS 131 502 502 LYS LYS E . n 
D 2 132 LEU 132 503 503 LEU LEU E . n 
D 2 133 ALA 133 504 504 ALA ALA E . n 
D 2 134 LYS 134 505 505 LYS LYS E . n 
D 2 135 GLN 135 506 506 GLN GLN E . n 
D 2 136 ARG 136 507 507 ARG ARG E . n 
D 2 137 SER 137 508 508 SER SER E . n 
D 2 138 VAL 138 509 509 VAL VAL E . n 
D 2 139 CYS 139 510 510 CYS CYS E . n 
D 2 140 THR 140 511 511 THR THR E . n 
D 2 141 TRP 141 512 512 TRP TRP E . n 
D 2 142 GLY 142 513 513 GLY GLY E . n 
D 2 143 LYS 143 514 514 LYS LYS E . n 
D 2 144 ASN 144 515 515 ASN ASN E . n 
D 2 145 LYS 145 516 516 LYS LYS E . n 
D 2 146 PRO 146 517 517 PRO PRO E . n 
D 2 147 GLY 147 518 518 GLY GLY E . n 
D 2 148 ILE 148 519 519 ILE ILE E . n 
D 2 149 GLY 149 520 520 GLY GLY E . n 
D 2 150 ALA 150 521 521 ALA ALA E . n 
D 2 151 VAL 151 522 522 VAL VAL E . n 
D 2 152 ILE 152 523 523 ILE ILE E . n 
D 2 153 LEU 153 524 524 LEU LEU E . n 
D 2 154 LYS 154 525 525 LYS LYS E . n 
D 2 155 ARG 155 526 526 ARG ARG E . n 
D 2 156 ALA 156 527 527 ALA ALA E . n 
D 2 157 LYS 157 528 528 LYS LYS E . n 
D 2 158 ALA 158 529 529 ALA ALA E . n 
D 2 159 LEU 159 530 530 LEU LEU E . n 
D 2 160 ALA 160 531 531 ALA ALA E . n 
D 2 161 GLY 161 532 532 GLY GLY E . n 
D 2 162 GLN 162 533 533 GLN GLN E . n 
D 2 163 SER 163 534 534 SER SER E . n 
D 2 164 VAL 164 535 535 VAL VAL E . n 
D 2 165 ARG 165 536 536 ARG ARG E . n 
D 2 166 ILE 166 537 537 ILE ILE E . n 
D 2 167 CYS 167 538 538 CYS CYS E . n 
D 2 168 LYS 168 539 539 LYS LYS E . n 
D 2 169 GLY 169 540 540 GLY GLY E . n 
D 2 170 PRO 170 541 541 PRO PRO E . n 
D 2 171 ARG 171 542 542 ARG ARG E . n 
D 2 172 ALA 172 543 543 ALA ALA E . n 
D 2 173 VAL 173 544 544 VAL VAL E . n 
D 2 174 PHE 174 545 545 PHE PHE E . n 
D 2 175 SER 175 546 546 SER SER E . n 
D 2 176 ARG 176 547 547 ARG ARG E . n 
D 2 177 ILE 177 548 548 ILE ILE E . n 
D 2 178 LEU 178 549 549 LEU LEU E . n 
D 2 179 LEU 179 550 550 LEU LEU E . n 
D 2 180 LEU 180 551 551 LEU LEU E . n 
D 2 181 PHE 181 552 552 PHE PHE E . n 
D 2 182 SER 182 553 553 SER SER E . n 
D 2 183 LEU 183 554 554 LEU LEU E . n 
E 3 1   DC  1   1   1   DC  DC  A . n 
E 3 2   DG  2   2   2   DG  DG  A . n 
E 3 3   DA  3   3   3   DA  DA  A . n 
E 3 4   DA  4   4   4   DA  DA  A . n 
E 3 5   DT  5   5   5   DT  DT  A . n 
E 3 6   DT  6   6   6   DT  DT  A . n 
E 3 7   DT  7   7   7   DT  DT  A . n 
E 3 8   DC  8   8   8   DC  DC  A . n 
E 3 9   DT  9   9   9   DT  DT  A . n 
E 3 10  DA  10  10  10  DA  DA  A . n 
E 3 11  DG  11  11  11  DG  DG  A . n 
E 3 12  DA  12  12  12  DA  DA  A . n 
E 3 13  DC  13  13  13  DC  DC  A . n 
E 3 14  DT  14  14  14  DT  DT  A . n 
E 3 15  DC  15  15  15  DC  DC  A . n 
E 3 16  DG  16  16  16  DG  DG  A . n 
E 3 17  DA  17  17  17  DA  DA  A . n 
E 3 18  DG  18  18  18  DG  DG  A . n 
E 3 19  DA  19  19  19  DA  DA  A . n 
E 3 20  DT  20  20  20  DT  DT  A . n 
E 3 21  DC  21  21  21  DC  DC  A . n 
E 3 22  DA  22  22  22  DA  DA  A . n 
E 3 23  DG  23  23  23  DG  DG  A . n 
F 4 1   DA  1   21  21  DA  DA  F . n 
F 4 2   DT  2   22  22  DT  DT  F . n 
F 4 3   DC  3   23  23  DC  DC  F . n 
F 4 4   DT  4   24  24  DT  DT  F . n 
F 4 5   DC  5   25  25  DC  DC  F . n 
F 4 6   DG  6   26  26  DG  DG  F . n 
F 4 7   DA  7   27  27  DA  DA  F . n 
F 4 8   DG  8   28  28  DG  DG  F . n 
F 4 9   DT  9   29  29  DT  DT  F . n 
F 4 10  DC  10  30  30  DC  DC  F . n 
F 4 11  DT  11  31  31  DT  DT  F . n 
F 4 12  DA  12  32  32  DA  DA  F . n 
F 4 13  DG  13  33  33  DG  DG  F . n 
F 4 14  DA  14  34  34  DA  DA  F . n 
F 4 15  DA  15  35  35  DA  DA  F . n 
F 4 16  DA  16  36  36  DA  DA  F . n 
F 4 17  DT  17  37  37  DT  DT  F . n 
F 4 18  DT  18  38  38  DT  DT  F . n 
F 4 19  DC  19  39  39  DC  DC  F . n 
F 4 20  DG  20  40  40  DG  DG  F . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CG4 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CG4 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CG4 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9CG4 
_struct.title                        
'Cryo-EM structure of FAN1, PCNA and DNA substrate with (CAG)2 extrusion in intermediate state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CG4 
_struct_keywords.text            
;nuclease, CAG expansion, DNA repair, Huntington's disease, DNA BINDING PROTEIN
;
_struct_keywords.pdbx_keywords   'DNA BINDING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP PCNA_HUMAN P12004 ? 1 
;MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILK
CAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVI
SCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYK
IADMGHLKYYLAPKIEDEEGS
;
1   
2 UNP FAN1_HUMAN Q9Y2M0 ? 2 
;HPYYLRSFLVVLKTVLENEDDMLLFDEQEKGIVTKFYQLSATGQKLYVRLFQRKLSWIKMTKLEYEEIALDLTPVIEELT
NAGFLQTESELQELSEVLELLSAPELKSLAKTFHLVNPNGQKQQLVDAFLKLAKQRSVCTWGKNKPGIGAVILKRAKALA
GQSVRICKGPRAVFSRILLLFSL
;
372 
3 PDB 9CG4       9CG4   ? 3 ? 1   
4 PDB 9CG4       9CG4   ? 4 ? 1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9CG4 B 1 ? 261 ? P12004 1   ? 261 ? 1   261 
2 1 9CG4 C 1 ? 261 ? P12004 1   ? 261 ? 1   261 
3 1 9CG4 D 1 ? 261 ? P12004 1   ? 261 ? 1   261 
4 2 9CG4 E 1 ? 183 ? Q9Y2M0 372 ? 554 ? 372 554 
5 3 9CG4 A 1 ? 23  ? 9CG4   1   ? 23  ? 1   23  
6 4 9CG4 F 1 ? 20  ? 9CG4   21  ? 40  ? 21  40  
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLN A 8   ? ASP A 21  ? GLN B 8   ASP B 21  1 ? 14 
HELX_P HELX_P2  AA2 LEU A 72  ? ALA A 82  ? LEU B 72  ALA B 82  1 ? 11 
HELX_P HELX_P3  AA3 PRO A 140 ? GLY A 155 ? PRO B 140 GLY B 155 1 ? 16 
HELX_P HELX_P4  AA4 LEU A 209 ? THR A 216 ? LEU B 209 THR B 216 1 ? 8  
HELX_P HELX_P5  AA5 LYS A 217 ? SER A 222 ? LYS B 217 SER B 222 5 ? 6  
HELX_P HELX_P6  AA6 ILE A 255 ? SER A 261 ? ILE B 255 SER B 261 1 ? 7  
HELX_P HELX_P7  AA7 GLN B 8   ? ASP B 21  ? GLN C 8   ASP C 21  1 ? 14 
HELX_P HELX_P8  AA8 LEU B 72  ? CYS B 81  ? LEU C 72  CYS C 81  1 ? 10 
HELX_P HELX_P9  AA9 SER B 141 ? GLY B 155 ? SER C 141 GLY C 155 1 ? 15 
HELX_P HELX_P10 AB1 LEU B 209 ? THR B 216 ? LEU C 209 THR C 216 1 ? 8  
HELX_P HELX_P11 AB2 LYS B 217 ? SER B 222 ? LYS C 217 SER C 222 5 ? 6  
HELX_P HELX_P12 AB3 ILE B 255 ? SER B 261 ? ILE C 255 SER C 261 5 ? 7  
HELX_P HELX_P13 AB4 GLN C 8   ? ASP C 21  ? GLN D 8   ASP D 21  1 ? 14 
HELX_P HELX_P14 AB5 LEU C 72  ? CYS C 81  ? LEU D 72  CYS D 81  1 ? 10 
HELX_P HELX_P15 AB6 SER C 141 ? SER C 152 ? SER D 141 SER D 152 1 ? 12 
HELX_P HELX_P16 AB7 ALA C 208 ? THR C 216 ? ALA D 208 THR D 216 1 ? 9  
HELX_P HELX_P17 AB8 LYS C 217 ? SER C 222 ? LYS D 217 SER D 222 5 ? 6  
HELX_P HELX_P18 AB9 PRO D 2   ? ASN D 18  ? PRO E 373 ASN E 389 1 ? 17 
HELX_P HELX_P19 AC1 ASP D 21  ? PHE D 25  ? ASP E 392 PHE E 396 5 ? 5  
HELX_P HELX_P20 AC2 ASP D 26  ? LEU D 39  ? ASP E 397 LEU E 410 1 ? 14 
HELX_P HELX_P21 AC3 SER D 40  ? ARG D 53  ? SER E 411 ARG E 424 1 ? 14 
HELX_P HELX_P22 AC4 THR D 61  ? LEU D 63  ? THR E 432 LEU E 434 5 ? 3  
HELX_P HELX_P23 AC5 LEU D 72  ? ALA D 82  ? LEU E 443 ALA E 453 1 ? 11 
HELX_P HELX_P24 AC6 SER D 89  ? LEU D 91  ? SER E 460 LEU E 462 5 ? 3  
HELX_P HELX_P25 AC7 GLU D 93  ? LEU D 101 ? GLU E 464 LEU E 472 1 ? 9  
HELX_P HELX_P26 AC8 SER D 102 ? PHE D 113 ? SER E 473 PHE E 484 1 ? 12 
HELX_P HELX_P27 AC9 GLN D 121 ? ALA D 133 ? GLN E 492 ALA E 504 1 ? 13 
HELX_P HELX_P28 AD1 VAL D 138 ? GLY D 142 ? VAL E 509 GLY E 513 5 ? 5  
HELX_P HELX_P29 AD2 GLY D 147 ? GLY D 161 ? GLY E 518 GLY E 532 1 ? 15 
HELX_P HELX_P30 AD3 CYS D 167 ? SER D 175 ? CYS E 538 SER E 546 1 ? 9  
HELX_P HELX_P31 AD4 ILE D 177 ? LEU D 183 ? ILE E 548 LEU E 554 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ? ? A CYS 135 SG ? ? ? 1_555 A CYS 162 SG ? ? B CYS 135 B CYS 162 1_555 ? ? ? ? ? ? ?               2.039 ? ? 
disulf2  disulf ? ? B CYS 135 SG ? ? ? 1_555 B CYS 162 SG ? ? C CYS 135 C CYS 162 1_555 ? ? ? ? ? ? ?               2.033 ? ? 
disulf3  disulf ? ? C CYS 135 SG ? ? ? 1_555 C CYS 162 SG ? ? D CYS 135 D CYS 162 1_555 ? ? ? ? ? ? ?               2.033 ? ? 
hydrog1  hydrog ? ? E DC  1   N3 ? ? ? 1_555 F DG  20  N1 ? ? A DC  1   F DG  40  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog2  hydrog ? ? E DC  1   N4 ? ? ? 1_555 F DG  20  O6 ? ? A DC  1   F DG  40  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog3  hydrog ? ? E DC  1   O2 ? ? ? 1_555 F DG  20  N2 ? ? A DC  1   F DG  40  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog4  hydrog ? ? E DG  2   O6 ? ? ? 1_555 F DC  19  N4 ? ? A DG  2   F DC  39  1_555 ? ? ? ? ? ? 'DG-DC PAIR'    ?     ? ? 
hydrog5  hydrog ? ? E DA  3   N6 ? ? ? 1_555 F DT  18  O4 ? ? A DA  3   F DT  38  1_555 ? ? ? ? ? ? 'DA-DT PAIR'    ?     ? ? 
hydrog6  hydrog ? ? E DA  4   N6 ? ? ? 1_555 F DT  17  O4 ? ? A DA  4   F DT  37  1_555 ? ? ? ? ? ? 'DA-DT PAIR'    ?     ? ? 
hydrog7  hydrog ? ? E DA  4   N1 ? ? ? 1_555 F DT  18  N3 ? ? A DA  4   F DT  38  1_555 ? ? ? ? ? ? 'DA-DT PAIR'    ?     ? ? 
hydrog8  hydrog ? ? E DT  5   N3 ? ? ? 1_555 F DA  16  N1 ? ? A DT  5   F DA  36  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog9  hydrog ? ? E DT  5   O4 ? ? ? 1_555 F DA  16  N6 ? ? A DT  5   F DA  36  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog10 hydrog ? ? E DT  6   N3 ? ? ? 1_555 F DA  15  N1 ? ? A DT  6   F DA  35  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog11 hydrog ? ? E DT  6   O4 ? ? ? 1_555 F DA  15  N6 ? ? A DT  6   F DA  35  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog12 hydrog ? ? E DT  7   N3 ? ? ? 1_555 F DA  14  N1 ? ? A DT  7   F DA  34  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog13 hydrog ? ? E DT  7   O4 ? ? ? 1_555 F DA  14  N6 ? ? A DT  7   F DA  34  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog14 hydrog ? ? E DC  8   N3 ? ? ? 1_555 F DG  13  N1 ? ? A DC  8   F DG  33  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog15 hydrog ? ? E DC  8   N4 ? ? ? 1_555 F DG  13  O6 ? ? A DC  8   F DG  33  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog16 hydrog ? ? E DC  8   O2 ? ? ? 1_555 F DG  13  N2 ? ? A DC  8   F DG  33  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog17 hydrog ? ? E DT  9   N3 ? ? ? 1_555 F DA  12  N1 ? ? A DT  9   F DA  32  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog18 hydrog ? ? E DT  9   O4 ? ? ? 1_555 F DA  12  N6 ? ? A DT  9   F DA  32  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog19 hydrog ? ? E DA  10  N1 ? ? ? 1_555 F DT  11  N3 ? ? A DA  10  F DT  31  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog20 hydrog ? ? E DA  10  N6 ? ? ? 1_555 F DT  11  O4 ? ? A DA  10  F DT  31  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog21 hydrog ? ? E DG  11  N1 ? ? ? 1_555 F DC  10  N3 ? ? A DG  11  F DC  30  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog22 hydrog ? ? E DG  11  N2 ? ? ? 1_555 F DC  10  O2 ? ? A DG  11  F DC  30  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog23 hydrog ? ? E DG  11  O6 ? ? ? 1_555 F DC  10  N4 ? ? A DG  11  F DC  30  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog24 hydrog ? ? E DA  12  N1 ? ? ? 1_555 F DT  9   N3 ? ? A DA  12  F DT  29  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog25 hydrog ? ? E DA  12  N6 ? ? ? 1_555 F DT  9   O4 ? ? A DA  12  F DT  29  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog26 hydrog ? ? E DC  13  N3 ? ? ? 1_555 F DG  8   N1 ? ? A DC  13  F DG  28  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog27 hydrog ? ? E DC  13  N4 ? ? ? 1_555 F DG  8   O6 ? ? A DC  13  F DG  28  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog28 hydrog ? ? E DC  13  O2 ? ? ? 1_555 F DG  8   N2 ? ? A DC  13  F DG  28  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog29 hydrog ? ? E DC  13  N3 ? ? ? 1_555 F DT  9   N3 ? ? A DC  13  F DT  29  1_555 ? ? ? ? ? ? TYPE_18_PAIR    ?     ? ? 
hydrog30 hydrog ? ? E DC  13  N4 ? ? ? 1_555 F DT  9   O4 ? ? A DC  13  F DT  29  1_555 ? ? ? ? ? ? TYPE_18_PAIR    ?     ? ? 
hydrog31 hydrog ? ? E DT  14  N3 ? ? ? 1_555 F DA  7   N1 ? ? A DT  14  F DA  27  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog32 hydrog ? ? E DT  14  O4 ? ? ? 1_555 F DA  7   N6 ? ? A DT  14  F DA  27  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog33 hydrog ? ? E DC  15  N3 ? ? ? 1_555 F DG  6   N1 ? ? A DC  15  F DG  26  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog34 hydrog ? ? E DC  15  N4 ? ? ? 1_555 F DG  6   O6 ? ? A DC  15  F DG  26  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog35 hydrog ? ? E DC  15  O2 ? ? ? 1_555 F DG  6   N2 ? ? A DC  15  F DG  26  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog36 hydrog ? ? E DG  16  N1 ? ? ? 1_555 F DC  5   N3 ? ? A DG  16  F DC  25  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog37 hydrog ? ? E DG  16  N2 ? ? ? 1_555 F DC  5   O2 ? ? A DG  16  F DC  25  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog38 hydrog ? ? E DG  16  O6 ? ? ? 1_555 F DC  5   N4 ? ? A DG  16  F DC  25  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog39 hydrog ? ? E DA  17  N1 ? ? ? 1_555 F DT  4   N3 ? ? A DA  17  F DT  24  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog40 hydrog ? ? E DA  17  N6 ? ? ? 1_555 F DT  4   O4 ? ? A DA  17  F DT  24  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog41 hydrog ? ? E DG  18  N2 ? ? ? 1_555 F DC  3   O2 ? ? A DG  18  F DC  23  1_555 ? ? ? ? ? ? 'DG-DC PAIR'    ?     ? ? 
hydrog42 hydrog ? ? E DG  18  N2 ? ? ? 1_555 F DT  4   O2 ? ? A DG  18  F DT  24  1_555 ? ? ? ? ? ? 'DG-DT MISPAIR' ?     ? ? 
hydrog43 hydrog ? ? E DA  19  N1 ? ? ? 1_555 F DT  2   N3 ? ? A DA  19  F DT  22  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog44 hydrog ? ? E DA  19  N6 ? ? ? 1_555 F DT  2   O4 ? ? A DA  19  F DT  22  1_555 ? ? ? ? ? ? WATSON-CRICK    ?     ? ? 
hydrog45 hydrog ? ? E DT  20  N3 ? ? ? 1_555 F DA  1   N1 ? ? A DT  20  F DA  21  1_555 ? ? ? ? ? ? 'DT-DA PAIR'    ?     ? ? 
hydrog46 hydrog ? ? E DC  21  N3 ? ? ? 1_555 F DA  1   N6 ? ? A DC  21  F DA  21  1_555 ? ? ? ? ? ? 'DC-DA MISPAIR' ?     ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
hydrog ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 135 ? CYS A 162 ? CYS B 135 ? 1_555 CYS B 162 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 135 ? CYS B 162 ? CYS C 135 ? 1_555 CYS C 162 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS C 135 ? CYS C 162 ? CYS D 135 ? 1_555 CYS D 162 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 3 ? 
AA5 ? 2 ? 
AA6 ? 3 ? 
AA7 ? 3 ? 
AA8 ? 2 ? 
AA9 ? 7 ? 
AB1 ? 4 ? 
AB2 ? 2 ? 
AB3 ? 3 ? 
AB4 ? 9 ? 
AB5 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AA9 6 7 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
AB4 6 7 ? anti-parallel 
AB4 7 8 ? anti-parallel 
AB4 8 9 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 59  ? ARG A 61  ? THR B 59  ARG B 61  
AA1 2 PHE A 2   ? ARG A 5   ? PHE B 2   ARG B 5   
AA1 3 ARG A 91  ? ALA A 92  ? ARG B 91  ALA B 92  
AA2 1 LEU A 66  ? ASN A 71  ? LEU B 66  ASN B 71  
AA2 2 GLU A 25  ? ILE A 30  ? GLU B 25  ILE B 30  
AA2 3 GLY A 34  ? GLN A 38  ? GLY B 34  GLN B 38  
AA2 4 SER A 46  ? ARG A 53  ? SER B 46  ARG B 53  
AA2 5 GLY A 245 ? LEU A 251 ? GLY B 245 LEU B 251 
AA2 6 LEU A 235 ? ILE A 241 ? LEU B 235 ILE B 241 
AA3 1 ALA A 100 ? GLU A 104 ? ALA B 100 GLU B 104 
AA3 2 LYS A 110 ? GLU A 115 ? LYS B 110 GLU B 115 
AA3 3 GLY B 176 ? LEU B 182 ? GLY C 176 LEU C 182 
AA3 4 LYS B 168 ? GLY B 173 ? LYS C 168 GLY C 173 
AA4 1 ILE A 197 ? MET A 199 ? ILE B 197 MET B 199 
AA4 2 CYS A 135 ? VAL A 137 ? CYS B 135 VAL B 137 
AA4 3 SER A 228 ? MET A 229 ? SER B 228 MET B 229 
AA5 1 ALA A 157 ? VAL A 158 ? ALA B 157 VAL B 158 
AA5 2 PHE A 207 ? ALA A 208 ? PHE B 207 ALA B 208 
AA6 1 ASN A 179 ? LEU A 182 ? ASN B 179 LEU B 182 
AA6 2 LYS C 110 ? LYS C 117 ? LYS D 110 LYS D 117 
AA6 3 THR C 98  ? LEU C 101 ? THR D 98  LEU D 101 
AA7 1 THR B 59  ? ARG B 61  ? THR C 59  ARG C 61  
AA7 2 PHE B 2   ? ARG B 5   ? PHE C 2   ARG C 5   
AA7 3 ARG B 91  ? ALA B 92  ? ARG C 91  ALA C 92  
AA8 1 GLU B 25  ? CYS B 27  ? GLU C 25  CYS C 27  
AA8 2 GLY B 69  ? ASN B 71  ? GLY C 69  ASN C 71  
AA9 1 LEU B 37  ? SER B 39  ? LEU C 37  SER C 39  
AA9 2 VAL B 48  ? LEU B 50  ? VAL C 48  LEU C 50  
AA9 3 GLY B 245 ? LEU B 251 ? GLY C 245 LEU C 251 
AA9 4 LEU B 235 ? ILE B 241 ? LEU C 235 ILE C 241 
AA9 5 THR B 224 ? MET B 229 ? THR C 224 MET C 229 
AA9 6 CYS B 135 ? PRO B 140 ? CYS C 135 PRO C 140 
AA9 7 ILE B 197 ? GLU B 198 ? ILE C 197 GLU C 198 
AB1 1 VAL B 102 ? PHE B 103 ? VAL C 102 PHE C 103 
AB1 2 LYS B 110 ? ASP B 113 ? LYS C 110 ASP C 113 
AB1 3 ASN C 177 ? LEU C 182 ? ASN D 177 LEU D 182 
AB1 4 LYS C 168 ? SER C 172 ? LYS D 168 SER D 172 
AB2 1 ALA B 157 ? VAL B 158 ? ALA C 157 VAL C 158 
AB2 2 PHE B 207 ? ALA B 208 ? PHE C 207 ALA C 208 
AB3 1 THR C 59  ? CYS C 62  ? THR D 59  CYS D 62  
AB3 2 PHE C 2   ? ARG C 5   ? PHE D 2   ARG D 5   
AB3 3 ARG C 91  ? ALA C 92  ? ARG D 91  ALA D 92  
AB4 1 LEU C 66  ? ASN C 71  ? LEU D 66  ASN D 71  
AB4 2 GLU C 25  ? ILE C 30  ? GLU D 25  ILE D 30  
AB4 3 GLY C 34  ? MET C 40  ? GLY D 34  MET D 40  
AB4 4 SER C 46  ? ARG C 53  ? SER D 46  ARG D 53  
AB4 5 GLY C 245 ? LEU C 251 ? GLY D 245 LEU D 251 
AB4 6 VAL C 233 ? ILE C 241 ? VAL D 233 ILE D 241 
AB4 7 THR C 224 ? SER C 230 ? THR D 224 SER D 230 
AB4 8 CYS C 135 ? PRO C 140 ? CYS D 135 PRO D 140 
AB4 9 THR C 196 ? GLU C 198 ? THR D 196 GLU D 198 
AB5 1 ILE D 58  ? LYS D 59  ? ILE E 429 LYS E 430 
AB5 2 SER D 163 ? ILE D 166 ? SER E 534 ILE E 537 
AB5 3 LEU D 85  ? THR D 87  ? LEU E 456 THR E 458 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O THR A 59  ? O THR B 59  N ARG A 5   ? N ARG B 5   
AA1 2 3 N PHE A 2   ? N PHE B 2   O ALA A 92  ? O ALA B 92  
AA2 1 2 O MET A 68  ? O MET B 68  N TRP A 28  ? N TRP B 28  
AA2 2 3 N ASP A 29  ? N ASP B 29  O ASN A 36  ? O ASN B 36  
AA2 3 4 N VAL A 35  ? N VAL B 35  O LEU A 52  ? O LEU B 52  
AA2 4 5 N LEU A 47  ? N LEU B 47  O TYR A 250 ? O TYR B 250 
AA2 5 6 O LEU A 251 ? O LEU B 251 N LEU A 235 ? N LEU B 235 
AA3 1 2 N LEU A 101 ? N LEU B 101 O TYR A 114 ? O TYR B 114 
AA3 2 3 N ASP A 113 ? N ASP B 113 O ASN B 179 ? O ASN C 179 
AA3 3 4 O GLY B 176 ? O GLY C 176 N GLY B 173 ? N GLY C 173 
AA4 1 2 O GLU A 198 ? O GLU B 198 N VAL A 136 ? N VAL B 136 
AA4 2 3 N CYS A 135 ? N CYS B 135 O MET A 229 ? O MET B 229 
AA5 1 2 N VAL A 158 ? N VAL B 158 O PHE A 207 ? O PHE B 207 
AA6 1 2 N ASN A 179 ? N ASN B 179 O ASP C 113 ? O ASP D 113 
AA6 2 3 O TYR C 114 ? O TYR D 114 N LEU C 101 ? N LEU D 101 
AA7 1 2 O THR B 59  ? O THR C 59  N ARG B 5   ? N ARG C 5   
AA7 2 3 N PHE B 2   ? N PHE C 2   O ALA B 92  ? O ALA C 92  
AA8 1 2 N ALA B 26  ? N ALA C 26  O VAL B 70  ? O VAL C 70  
AA9 1 2 N LEU B 37  ? N LEU C 37  O LEU B 50  ? O LEU C 50  
AA9 2 3 N GLN B 49  ? N GLN C 49  O LYS B 248 ? O LYS C 248 
AA9 3 4 O LEU B 247 ? O LEU C 247 N TYR B 239 ? N TYR C 239 
AA9 4 5 O VAL B 236 ? O VAL C 236 N SER B 228 ? N SER C 228 
AA9 5 6 O LEU B 227 ? O LEU C 227 N VAL B 137 ? N VAL C 137 
AA9 6 7 N VAL B 136 ? N VAL C 136 O GLU B 198 ? O GLU C 198 
AB1 1 2 N PHE B 103 ? N PHE C 103 O SER B 112 ? O SER C 112 
AB1 2 3 N ASP B 113 ? N ASP C 113 O ASN C 179 ? O ASN D 179 
AB1 3 4 O ILE C 180 ? O ILE D 180 N PHE C 169 ? N PHE D 169 
AB2 1 2 N VAL B 158 ? N VAL C 158 O PHE B 207 ? O PHE C 207 
AB3 1 2 O THR C 59  ? O THR D 59  N ARG C 5   ? N ARG D 5   
AB3 2 3 N PHE C 2   ? N PHE D 2   O ALA C 92  ? O ALA D 92  
AB4 1 2 O MET C 68  ? O MET D 68  N TRP C 28  ? N TRP D 28  
AB4 2 3 N ASP C 29  ? N ASP D 29  O ASN C 36  ? O ASN D 36  
AB4 3 4 N VAL C 35  ? N VAL D 35  O LEU C 52  ? O LEU D 52  
AB4 4 5 N LEU C 47  ? N LEU D 47  O TYR C 250 ? O TYR D 250 
AB4 5 6 O LEU C 247 ? O LEU D 247 N TYR C 239 ? N TYR D 239 
AB4 6 7 O VAL C 236 ? O VAL D 236 N SER C 228 ? N SER D 228 
AB4 7 8 O LEU C 227 ? O LEU D 227 N VAL C 137 ? N VAL D 137 
AB4 8 9 N LYS C 138 ? N LYS D 138 O THR C 196 ? O THR D 196 
AB5 1 2 N ILE D 58  ? N ILE E 429 O VAL D 164 ? O VAL E 535 
AB5 2 3 O ARG D 165 ? O ARG E 536 N GLN D 86  ? N GLN E 457 
# 
_pdbx_entry_details.entry_id                   9CG4 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            P 
_pdbx_validate_rmsd_bond.auth_asym_id_1            A 
_pdbx_validate_rmsd_bond.auth_comp_id_1            DC 
_pdbx_validate_rmsd_bond.auth_seq_id_1             1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            OP3 
_pdbx_validate_rmsd_bond.auth_asym_id_2            A 
_pdbx_validate_rmsd_bond.auth_comp_id_2            DC 
_pdbx_validate_rmsd_bond.auth_seq_id_2             1 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.480 
_pdbx_validate_rmsd_bond.bond_target_value         1.607 
_pdbx_validate_rmsd_bond.bond_deviation            -0.127 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.012 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLU B 85  ? ? -140.07 19.25   
2  1 ASP B 94  ? ? 54.56   -125.16 
3  1 GLN B 108 ? ? 33.61   58.23   
4  1 SER B 134 ? ? -95.20  -60.65  
5  1 CYS B 162 ? ? -36.73  122.29  
6  1 PHE B 169 ? ? -66.35  77.00   
7  1 ASP B 232 ? ? 31.38   49.50   
8  1 ALA B 242 ? ? 50.24   -112.43 
9  1 SER C 39  ? ? -125.26 -160.14 
10 1 ASN C 95  ? ? 39.91   54.82   
11 1 GLN C 108 ? ? 33.96   57.85   
12 1 ALA C 242 ? ? 50.08   -122.54 
13 1 PHE D 103 ? ? -37.15  128.82  
14 1 GLN D 108 ? ? 35.21   48.78   
15 1 GLU D 193 ? ? -93.39  53.16   
16 1 THR D 216 ? ? -68.74  4.88    
17 1 ALA D 242 ? ? 48.09   -116.94 
18 1 CYS E 510 ? ? -55.57  -6.14   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9CG4 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      OTHER 
# 
_em_3d_reconstruction.entry_id                    9CG4 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.37 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               300000 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Ternary complex of FAN1-PCNA-DNA in intermediate state' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4' 
# 
_em_imaging.entry_id                        9CG4 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            OTHER 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9CG4 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9CG4 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N N N 1   
ALA CA     C N S 2   
ALA C      C N N 3   
ALA O      O N N 4   
ALA CB     C N N 5   
ALA OXT    O N N 6   
ALA H      H N N 7   
ALA H2     H N N 8   
ALA HA     H N N 9   
ALA HB1    H N N 10  
ALA HB2    H N N 11  
ALA HB3    H N N 12  
ALA HXT    H N N 13  
ARG N      N N N 14  
ARG CA     C N S 15  
ARG C      C N N 16  
ARG O      O N N 17  
ARG CB     C N N 18  
ARG CG     C N N 19  
ARG CD     C N N 20  
ARG NE     N N N 21  
ARG CZ     C N N 22  
ARG NH1    N N N 23  
ARG NH2    N N N 24  
ARG OXT    O N N 25  
ARG H      H N N 26  
ARG H2     H N N 27  
ARG HA     H N N 28  
ARG HB2    H N N 29  
ARG HB3    H N N 30  
ARG HG2    H N N 31  
ARG HG3    H N N 32  
ARG HD2    H N N 33  
ARG HD3    H N N 34  
ARG HE     H N N 35  
ARG HH11   H N N 36  
ARG HH12   H N N 37  
ARG HH21   H N N 38  
ARG HH22   H N N 39  
ARG HXT    H N N 40  
ASN N      N N N 41  
ASN CA     C N S 42  
ASN C      C N N 43  
ASN O      O N N 44  
ASN CB     C N N 45  
ASN CG     C N N 46  
ASN OD1    O N N 47  
ASN ND2    N N N 48  
ASN OXT    O N N 49  
ASN H      H N N 50  
ASN H2     H N N 51  
ASN HA     H N N 52  
ASN HB2    H N N 53  
ASN HB3    H N N 54  
ASN HD21   H N N 55  
ASN HD22   H N N 56  
ASN HXT    H N N 57  
ASP N      N N N 58  
ASP CA     C N S 59  
ASP C      C N N 60  
ASP O      O N N 61  
ASP CB     C N N 62  
ASP CG     C N N 63  
ASP OD1    O N N 64  
ASP OD2    O N N 65  
ASP OXT    O N N 66  
ASP H      H N N 67  
ASP H2     H N N 68  
ASP HA     H N N 69  
ASP HB2    H N N 70  
ASP HB3    H N N 71  
ASP HD2    H N N 72  
ASP HXT    H N N 73  
CYS N      N N N 74  
CYS CA     C N R 75  
CYS C      C N N 76  
CYS O      O N N 77  
CYS CB     C N N 78  
CYS SG     S N N 79  
CYS OXT    O N N 80  
CYS H      H N N 81  
CYS H2     H N N 82  
CYS HA     H N N 83  
CYS HB2    H N N 84  
CYS HB3    H N N 85  
CYS HG     H N N 86  
CYS HXT    H N N 87  
DA  OP3    O N N 88  
DA  P      P N N 89  
DA  OP1    O N N 90  
DA  OP2    O N N 91  
DA  "O5'"  O N N 92  
DA  "C5'"  C N N 93  
DA  "C4'"  C N R 94  
DA  "O4'"  O N N 95  
DA  "C3'"  C N S 96  
DA  "O3'"  O N N 97  
DA  "C2'"  C N N 98  
DA  "C1'"  C N R 99  
DA  N9     N Y N 100 
DA  C8     C Y N 101 
DA  N7     N Y N 102 
DA  C5     C Y N 103 
DA  C6     C Y N 104 
DA  N6     N N N 105 
DA  N1     N Y N 106 
DA  C2     C Y N 107 
DA  N3     N Y N 108 
DA  C4     C Y N 109 
DA  HOP3   H N N 110 
DA  HOP2   H N N 111 
DA  "H5'"  H N N 112 
DA  "H5''" H N N 113 
DA  "H4'"  H N N 114 
DA  "H3'"  H N N 115 
DA  "HO3'" H N N 116 
DA  "H2'"  H N N 117 
DA  "H2''" H N N 118 
DA  "H1'"  H N N 119 
DA  H8     H N N 120 
DA  H61    H N N 121 
DA  H62    H N N 122 
DA  H2     H N N 123 
DC  OP3    O N N 124 
DC  P      P N N 125 
DC  OP1    O N N 126 
DC  OP2    O N N 127 
DC  "O5'"  O N N 128 
DC  "C5'"  C N N 129 
DC  "C4'"  C N R 130 
DC  "O4'"  O N N 131 
DC  "C3'"  C N S 132 
DC  "O3'"  O N N 133 
DC  "C2'"  C N N 134 
DC  "C1'"  C N R 135 
DC  N1     N N N 136 
DC  C2     C N N 137 
DC  O2     O N N 138 
DC  N3     N N N 139 
DC  C4     C N N 140 
DC  N4     N N N 141 
DC  C5     C N N 142 
DC  C6     C N N 143 
DC  HOP3   H N N 144 
DC  HOP2   H N N 145 
DC  "H5'"  H N N 146 
DC  "H5''" H N N 147 
DC  "H4'"  H N N 148 
DC  "H3'"  H N N 149 
DC  "HO3'" H N N 150 
DC  "H2'"  H N N 151 
DC  "H2''" H N N 152 
DC  "H1'"  H N N 153 
DC  H41    H N N 154 
DC  H42    H N N 155 
DC  H5     H N N 156 
DC  H6     H N N 157 
DG  OP3    O N N 158 
DG  P      P N N 159 
DG  OP1    O N N 160 
DG  OP2    O N N 161 
DG  "O5'"  O N N 162 
DG  "C5'"  C N N 163 
DG  "C4'"  C N R 164 
DG  "O4'"  O N N 165 
DG  "C3'"  C N S 166 
DG  "O3'"  O N N 167 
DG  "C2'"  C N N 168 
DG  "C1'"  C N R 169 
DG  N9     N Y N 170 
DG  C8     C Y N 171 
DG  N7     N Y N 172 
DG  C5     C Y N 173 
DG  C6     C N N 174 
DG  O6     O N N 175 
DG  N1     N N N 176 
DG  C2     C N N 177 
DG  N2     N N N 178 
DG  N3     N N N 179 
DG  C4     C Y N 180 
DG  HOP3   H N N 181 
DG  HOP2   H N N 182 
DG  "H5'"  H N N 183 
DG  "H5''" H N N 184 
DG  "H4'"  H N N 185 
DG  "H3'"  H N N 186 
DG  "HO3'" H N N 187 
DG  "H2'"  H N N 188 
DG  "H2''" H N N 189 
DG  "H1'"  H N N 190 
DG  H8     H N N 191 
DG  H1     H N N 192 
DG  H21    H N N 193 
DG  H22    H N N 194 
DT  OP3    O N N 195 
DT  P      P N N 196 
DT  OP1    O N N 197 
DT  OP2    O N N 198 
DT  "O5'"  O N N 199 
DT  "C5'"  C N N 200 
DT  "C4'"  C N R 201 
DT  "O4'"  O N N 202 
DT  "C3'"  C N S 203 
DT  "O3'"  O N N 204 
DT  "C2'"  C N N 205 
DT  "C1'"  C N R 206 
DT  N1     N N N 207 
DT  C2     C N N 208 
DT  O2     O N N 209 
DT  N3     N N N 210 
DT  C4     C N N 211 
DT  O4     O N N 212 
DT  C5     C N N 213 
DT  C7     C N N 214 
DT  C6     C N N 215 
DT  HOP3   H N N 216 
DT  HOP2   H N N 217 
DT  "H5'"  H N N 218 
DT  "H5''" H N N 219 
DT  "H4'"  H N N 220 
DT  "H3'"  H N N 221 
DT  "HO3'" H N N 222 
DT  "H2'"  H N N 223 
DT  "H2''" H N N 224 
DT  "H1'"  H N N 225 
DT  H3     H N N 226 
DT  H71    H N N 227 
DT  H72    H N N 228 
DT  H73    H N N 229 
DT  H6     H N N 230 
GLN N      N N N 231 
GLN CA     C N S 232 
GLN C      C N N 233 
GLN O      O N N 234 
GLN CB     C N N 235 
GLN CG     C N N 236 
GLN CD     C N N 237 
GLN OE1    O N N 238 
GLN NE2    N N N 239 
GLN OXT    O N N 240 
GLN H      H N N 241 
GLN H2     H N N 242 
GLN HA     H N N 243 
GLN HB2    H N N 244 
GLN HB3    H N N 245 
GLN HG2    H N N 246 
GLN HG3    H N N 247 
GLN HE21   H N N 248 
GLN HE22   H N N 249 
GLN HXT    H N N 250 
GLU N      N N N 251 
GLU CA     C N S 252 
GLU C      C N N 253 
GLU O      O N N 254 
GLU CB     C N N 255 
GLU CG     C N N 256 
GLU CD     C N N 257 
GLU OE1    O N N 258 
GLU OE2    O N N 259 
GLU OXT    O N N 260 
GLU H      H N N 261 
GLU H2     H N N 262 
GLU HA     H N N 263 
GLU HB2    H N N 264 
GLU HB3    H N N 265 
GLU HG2    H N N 266 
GLU HG3    H N N 267 
GLU HE2    H N N 268 
GLU HXT    H N N 269 
GLY N      N N N 270 
GLY CA     C N N 271 
GLY C      C N N 272 
GLY O      O N N 273 
GLY OXT    O N N 274 
GLY H      H N N 275 
GLY H2     H N N 276 
GLY HA2    H N N 277 
GLY HA3    H N N 278 
GLY HXT    H N N 279 
HIS N      N N N 280 
HIS CA     C N S 281 
HIS C      C N N 282 
HIS O      O N N 283 
HIS CB     C N N 284 
HIS CG     C Y N 285 
HIS ND1    N Y N 286 
HIS CD2    C Y N 287 
HIS CE1    C Y N 288 
HIS NE2    N Y N 289 
HIS OXT    O N N 290 
HIS H      H N N 291 
HIS H2     H N N 292 
HIS HA     H N N 293 
HIS HB2    H N N 294 
HIS HB3    H N N 295 
HIS HD1    H N N 296 
HIS HD2    H N N 297 
HIS HE1    H N N 298 
HIS HE2    H N N 299 
HIS HXT    H N N 300 
ILE N      N N N 301 
ILE CA     C N S 302 
ILE C      C N N 303 
ILE O      O N N 304 
ILE CB     C N S 305 
ILE CG1    C N N 306 
ILE CG2    C N N 307 
ILE CD1    C N N 308 
ILE OXT    O N N 309 
ILE H      H N N 310 
ILE H2     H N N 311 
ILE HA     H N N 312 
ILE HB     H N N 313 
ILE HG12   H N N 314 
ILE HG13   H N N 315 
ILE HG21   H N N 316 
ILE HG22   H N N 317 
ILE HG23   H N N 318 
ILE HD11   H N N 319 
ILE HD12   H N N 320 
ILE HD13   H N N 321 
ILE HXT    H N N 322 
LEU N      N N N 323 
LEU CA     C N S 324 
LEU C      C N N 325 
LEU O      O N N 326 
LEU CB     C N N 327 
LEU CG     C N N 328 
LEU CD1    C N N 329 
LEU CD2    C N N 330 
LEU OXT    O N N 331 
LEU H      H N N 332 
LEU H2     H N N 333 
LEU HA     H N N 334 
LEU HB2    H N N 335 
LEU HB3    H N N 336 
LEU HG     H N N 337 
LEU HD11   H N N 338 
LEU HD12   H N N 339 
LEU HD13   H N N 340 
LEU HD21   H N N 341 
LEU HD22   H N N 342 
LEU HD23   H N N 343 
LEU HXT    H N N 344 
LYS N      N N N 345 
LYS CA     C N S 346 
LYS C      C N N 347 
LYS O      O N N 348 
LYS CB     C N N 349 
LYS CG     C N N 350 
LYS CD     C N N 351 
LYS CE     C N N 352 
LYS NZ     N N N 353 
LYS OXT    O N N 354 
LYS H      H N N 355 
LYS H2     H N N 356 
LYS HA     H N N 357 
LYS HB2    H N N 358 
LYS HB3    H N N 359 
LYS HG2    H N N 360 
LYS HG3    H N N 361 
LYS HD2    H N N 362 
LYS HD3    H N N 363 
LYS HE2    H N N 364 
LYS HE3    H N N 365 
LYS HZ1    H N N 366 
LYS HZ2    H N N 367 
LYS HZ3    H N N 368 
LYS HXT    H N N 369 
MET N      N N N 370 
MET CA     C N S 371 
MET C      C N N 372 
MET O      O N N 373 
MET CB     C N N 374 
MET CG     C N N 375 
MET SD     S N N 376 
MET CE     C N N 377 
MET OXT    O N N 378 
MET H      H N N 379 
MET H2     H N N 380 
MET HA     H N N 381 
MET HB2    H N N 382 
MET HB3    H N N 383 
MET HG2    H N N 384 
MET HG3    H N N 385 
MET HE1    H N N 386 
MET HE2    H N N 387 
MET HE3    H N N 388 
MET HXT    H N N 389 
PHE N      N N N 390 
PHE CA     C N S 391 
PHE C      C N N 392 
PHE O      O N N 393 
PHE CB     C N N 394 
PHE CG     C Y N 395 
PHE CD1    C Y N 396 
PHE CD2    C Y N 397 
PHE CE1    C Y N 398 
PHE CE2    C Y N 399 
PHE CZ     C Y N 400 
PHE OXT    O N N 401 
PHE H      H N N 402 
PHE H2     H N N 403 
PHE HA     H N N 404 
PHE HB2    H N N 405 
PHE HB3    H N N 406 
PHE HD1    H N N 407 
PHE HD2    H N N 408 
PHE HE1    H N N 409 
PHE HE2    H N N 410 
PHE HZ     H N N 411 
PHE HXT    H N N 412 
PRO N      N N N 413 
PRO CA     C N S 414 
PRO C      C N N 415 
PRO O      O N N 416 
PRO CB     C N N 417 
PRO CG     C N N 418 
PRO CD     C N N 419 
PRO OXT    O N N 420 
PRO H      H N N 421 
PRO HA     H N N 422 
PRO HB2    H N N 423 
PRO HB3    H N N 424 
PRO HG2    H N N 425 
PRO HG3    H N N 426 
PRO HD2    H N N 427 
PRO HD3    H N N 428 
PRO HXT    H N N 429 
SER N      N N N 430 
SER CA     C N S 431 
SER C      C N N 432 
SER O      O N N 433 
SER CB     C N N 434 
SER OG     O N N 435 
SER OXT    O N N 436 
SER H      H N N 437 
SER H2     H N N 438 
SER HA     H N N 439 
SER HB2    H N N 440 
SER HB3    H N N 441 
SER HG     H N N 442 
SER HXT    H N N 443 
THR N      N N N 444 
THR CA     C N S 445 
THR C      C N N 446 
THR O      O N N 447 
THR CB     C N R 448 
THR OG1    O N N 449 
THR CG2    C N N 450 
THR OXT    O N N 451 
THR H      H N N 452 
THR H2     H N N 453 
THR HA     H N N 454 
THR HB     H N N 455 
THR HG1    H N N 456 
THR HG21   H N N 457 
THR HG22   H N N 458 
THR HG23   H N N 459 
THR HXT    H N N 460 
TRP N      N N N 461 
TRP CA     C N S 462 
TRP C      C N N 463 
TRP O      O N N 464 
TRP CB     C N N 465 
TRP CG     C Y N 466 
TRP CD1    C Y N 467 
TRP CD2    C Y N 468 
TRP NE1    N Y N 469 
TRP CE2    C Y N 470 
TRP CE3    C Y N 471 
TRP CZ2    C Y N 472 
TRP CZ3    C Y N 473 
TRP CH2    C Y N 474 
TRP OXT    O N N 475 
TRP H      H N N 476 
TRP H2     H N N 477 
TRP HA     H N N 478 
TRP HB2    H N N 479 
TRP HB3    H N N 480 
TRP HD1    H N N 481 
TRP HE1    H N N 482 
TRP HE3    H N N 483 
TRP HZ2    H N N 484 
TRP HZ3    H N N 485 
TRP HH2    H N N 486 
TRP HXT    H N N 487 
TYR N      N N N 488 
TYR CA     C N S 489 
TYR C      C N N 490 
TYR O      O N N 491 
TYR CB     C N N 492 
TYR CG     C Y N 493 
TYR CD1    C Y N 494 
TYR CD2    C Y N 495 
TYR CE1    C Y N 496 
TYR CE2    C Y N 497 
TYR CZ     C Y N 498 
TYR OH     O N N 499 
TYR OXT    O N N 500 
TYR H      H N N 501 
TYR H2     H N N 502 
TYR HA     H N N 503 
TYR HB2    H N N 504 
TYR HB3    H N N 505 
TYR HD1    H N N 506 
TYR HD2    H N N 507 
TYR HE1    H N N 508 
TYR HE2    H N N 509 
TYR HH     H N N 510 
TYR HXT    H N N 511 
VAL N      N N N 512 
VAL CA     C N S 513 
VAL C      C N N 514 
VAL O      O N N 515 
VAL CB     C N N 516 
VAL CG1    C N N 517 
VAL CG2    C N N 518 
VAL OXT    O N N 519 
VAL H      H N N 520 
VAL H2     H N N 521 
VAL HA     H N N 522 
VAL HB     H N N 523 
VAL HG11   H N N 524 
VAL HG12   H N N 525 
VAL HG13   H N N 526 
VAL HG21   H N N 527 
VAL HG22   H N N 528 
VAL HG23   H N N 529 
VAL HXT    H N N 530 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
DA  OP3   P      sing N N 83  
DA  OP3   HOP3   sing N N 84  
DA  P     OP1    doub N N 85  
DA  P     OP2    sing N N 86  
DA  P     "O5'"  sing N N 87  
DA  OP2   HOP2   sing N N 88  
DA  "O5'" "C5'"  sing N N 89  
DA  "C5'" "C4'"  sing N N 90  
DA  "C5'" "H5'"  sing N N 91  
DA  "C5'" "H5''" sing N N 92  
DA  "C4'" "O4'"  sing N N 93  
DA  "C4'" "C3'"  sing N N 94  
DA  "C4'" "H4'"  sing N N 95  
DA  "O4'" "C1'"  sing N N 96  
DA  "C3'" "O3'"  sing N N 97  
DA  "C3'" "C2'"  sing N N 98  
DA  "C3'" "H3'"  sing N N 99  
DA  "O3'" "HO3'" sing N N 100 
DA  "C2'" "C1'"  sing N N 101 
DA  "C2'" "H2'"  sing N N 102 
DA  "C2'" "H2''" sing N N 103 
DA  "C1'" N9     sing N N 104 
DA  "C1'" "H1'"  sing N N 105 
DA  N9    C8     sing Y N 106 
DA  N9    C4     sing Y N 107 
DA  C8    N7     doub Y N 108 
DA  C8    H8     sing N N 109 
DA  N7    C5     sing Y N 110 
DA  C5    C6     sing Y N 111 
DA  C5    C4     doub Y N 112 
DA  C6    N6     sing N N 113 
DA  C6    N1     doub Y N 114 
DA  N6    H61    sing N N 115 
DA  N6    H62    sing N N 116 
DA  N1    C2     sing Y N 117 
DA  C2    N3     doub Y N 118 
DA  C2    H2     sing N N 119 
DA  N3    C4     sing Y N 120 
DC  OP3   P      sing N N 121 
DC  OP3   HOP3   sing N N 122 
DC  P     OP1    doub N N 123 
DC  P     OP2    sing N N 124 
DC  P     "O5'"  sing N N 125 
DC  OP2   HOP2   sing N N 126 
DC  "O5'" "C5'"  sing N N 127 
DC  "C5'" "C4'"  sing N N 128 
DC  "C5'" "H5'"  sing N N 129 
DC  "C5'" "H5''" sing N N 130 
DC  "C4'" "O4'"  sing N N 131 
DC  "C4'" "C3'"  sing N N 132 
DC  "C4'" "H4'"  sing N N 133 
DC  "O4'" "C1'"  sing N N 134 
DC  "C3'" "O3'"  sing N N 135 
DC  "C3'" "C2'"  sing N N 136 
DC  "C3'" "H3'"  sing N N 137 
DC  "O3'" "HO3'" sing N N 138 
DC  "C2'" "C1'"  sing N N 139 
DC  "C2'" "H2'"  sing N N 140 
DC  "C2'" "H2''" sing N N 141 
DC  "C1'" N1     sing N N 142 
DC  "C1'" "H1'"  sing N N 143 
DC  N1    C2     sing N N 144 
DC  N1    C6     sing N N 145 
DC  C2    O2     doub N N 146 
DC  C2    N3     sing N N 147 
DC  N3    C4     doub N N 148 
DC  C4    N4     sing N N 149 
DC  C4    C5     sing N N 150 
DC  N4    H41    sing N N 151 
DC  N4    H42    sing N N 152 
DC  C5    C6     doub N N 153 
DC  C5    H5     sing N N 154 
DC  C6    H6     sing N N 155 
DG  OP3   P      sing N N 156 
DG  OP3   HOP3   sing N N 157 
DG  P     OP1    doub N N 158 
DG  P     OP2    sing N N 159 
DG  P     "O5'"  sing N N 160 
DG  OP2   HOP2   sing N N 161 
DG  "O5'" "C5'"  sing N N 162 
DG  "C5'" "C4'"  sing N N 163 
DG  "C5'" "H5'"  sing N N 164 
DG  "C5'" "H5''" sing N N 165 
DG  "C4'" "O4'"  sing N N 166 
DG  "C4'" "C3'"  sing N N 167 
DG  "C4'" "H4'"  sing N N 168 
DG  "O4'" "C1'"  sing N N 169 
DG  "C3'" "O3'"  sing N N 170 
DG  "C3'" "C2'"  sing N N 171 
DG  "C3'" "H3'"  sing N N 172 
DG  "O3'" "HO3'" sing N N 173 
DG  "C2'" "C1'"  sing N N 174 
DG  "C2'" "H2'"  sing N N 175 
DG  "C2'" "H2''" sing N N 176 
DG  "C1'" N9     sing N N 177 
DG  "C1'" "H1'"  sing N N 178 
DG  N9    C8     sing Y N 179 
DG  N9    C4     sing Y N 180 
DG  C8    N7     doub Y N 181 
DG  C8    H8     sing N N 182 
DG  N7    C5     sing Y N 183 
DG  C5    C6     sing N N 184 
DG  C5    C4     doub Y N 185 
DG  C6    O6     doub N N 186 
DG  C6    N1     sing N N 187 
DG  N1    C2     sing N N 188 
DG  N1    H1     sing N N 189 
DG  C2    N2     sing N N 190 
DG  C2    N3     doub N N 191 
DG  N2    H21    sing N N 192 
DG  N2    H22    sing N N 193 
DG  N3    C4     sing N N 194 
DT  OP3   P      sing N N 195 
DT  OP3   HOP3   sing N N 196 
DT  P     OP1    doub N N 197 
DT  P     OP2    sing N N 198 
DT  P     "O5'"  sing N N 199 
DT  OP2   HOP2   sing N N 200 
DT  "O5'" "C5'"  sing N N 201 
DT  "C5'" "C4'"  sing N N 202 
DT  "C5'" "H5'"  sing N N 203 
DT  "C5'" "H5''" sing N N 204 
DT  "C4'" "O4'"  sing N N 205 
DT  "C4'" "C3'"  sing N N 206 
DT  "C4'" "H4'"  sing N N 207 
DT  "O4'" "C1'"  sing N N 208 
DT  "C3'" "O3'"  sing N N 209 
DT  "C3'" "C2'"  sing N N 210 
DT  "C3'" "H3'"  sing N N 211 
DT  "O3'" "HO3'" sing N N 212 
DT  "C2'" "C1'"  sing N N 213 
DT  "C2'" "H2'"  sing N N 214 
DT  "C2'" "H2''" sing N N 215 
DT  "C1'" N1     sing N N 216 
DT  "C1'" "H1'"  sing N N 217 
DT  N1    C2     sing N N 218 
DT  N1    C6     sing N N 219 
DT  C2    O2     doub N N 220 
DT  C2    N3     sing N N 221 
DT  N3    C4     sing N N 222 
DT  N3    H3     sing N N 223 
DT  C4    O4     doub N N 224 
DT  C4    C5     sing N N 225 
DT  C5    C7     sing N N 226 
DT  C5    C6     doub N N 227 
DT  C7    H71    sing N N 228 
DT  C7    H72    sing N N 229 
DT  C7    H73    sing N N 230 
DT  C6    H6     sing N N 231 
GLN N     CA     sing N N 232 
GLN N     H      sing N N 233 
GLN N     H2     sing N N 234 
GLN CA    C      sing N N 235 
GLN CA    CB     sing N N 236 
GLN CA    HA     sing N N 237 
GLN C     O      doub N N 238 
GLN C     OXT    sing N N 239 
GLN CB    CG     sing N N 240 
GLN CB    HB2    sing N N 241 
GLN CB    HB3    sing N N 242 
GLN CG    CD     sing N N 243 
GLN CG    HG2    sing N N 244 
GLN CG    HG3    sing N N 245 
GLN CD    OE1    doub N N 246 
GLN CD    NE2    sing N N 247 
GLN NE2   HE21   sing N N 248 
GLN NE2   HE22   sing N N 249 
GLN OXT   HXT    sing N N 250 
GLU N     CA     sing N N 251 
GLU N     H      sing N N 252 
GLU N     H2     sing N N 253 
GLU CA    C      sing N N 254 
GLU CA    CB     sing N N 255 
GLU CA    HA     sing N N 256 
GLU C     O      doub N N 257 
GLU C     OXT    sing N N 258 
GLU CB    CG     sing N N 259 
GLU CB    HB2    sing N N 260 
GLU CB    HB3    sing N N 261 
GLU CG    CD     sing N N 262 
GLU CG    HG2    sing N N 263 
GLU CG    HG3    sing N N 264 
GLU CD    OE1    doub N N 265 
GLU CD    OE2    sing N N 266 
GLU OE2   HE2    sing N N 267 
GLU OXT   HXT    sing N N 268 
GLY N     CA     sing N N 269 
GLY N     H      sing N N 270 
GLY N     H2     sing N N 271 
GLY CA    C      sing N N 272 
GLY CA    HA2    sing N N 273 
GLY CA    HA3    sing N N 274 
GLY C     O      doub N N 275 
GLY C     OXT    sing N N 276 
GLY OXT   HXT    sing N N 277 
HIS N     CA     sing N N 278 
HIS N     H      sing N N 279 
HIS N     H2     sing N N 280 
HIS CA    C      sing N N 281 
HIS CA    CB     sing N N 282 
HIS CA    HA     sing N N 283 
HIS C     O      doub N N 284 
HIS C     OXT    sing N N 285 
HIS CB    CG     sing N N 286 
HIS CB    HB2    sing N N 287 
HIS CB    HB3    sing N N 288 
HIS CG    ND1    sing Y N 289 
HIS CG    CD2    doub Y N 290 
HIS ND1   CE1    doub Y N 291 
HIS ND1   HD1    sing N N 292 
HIS CD2   NE2    sing Y N 293 
HIS CD2   HD2    sing N N 294 
HIS CE1   NE2    sing Y N 295 
HIS CE1   HE1    sing N N 296 
HIS NE2   HE2    sing N N 297 
HIS OXT   HXT    sing N N 298 
ILE N     CA     sing N N 299 
ILE N     H      sing N N 300 
ILE N     H2     sing N N 301 
ILE CA    C      sing N N 302 
ILE CA    CB     sing N N 303 
ILE CA    HA     sing N N 304 
ILE C     O      doub N N 305 
ILE C     OXT    sing N N 306 
ILE CB    CG1    sing N N 307 
ILE CB    CG2    sing N N 308 
ILE CB    HB     sing N N 309 
ILE CG1   CD1    sing N N 310 
ILE CG1   HG12   sing N N 311 
ILE CG1   HG13   sing N N 312 
ILE CG2   HG21   sing N N 313 
ILE CG2   HG22   sing N N 314 
ILE CG2   HG23   sing N N 315 
ILE CD1   HD11   sing N N 316 
ILE CD1   HD12   sing N N 317 
ILE CD1   HD13   sing N N 318 
ILE OXT   HXT    sing N N 319 
LEU N     CA     sing N N 320 
LEU N     H      sing N N 321 
LEU N     H2     sing N N 322 
LEU CA    C      sing N N 323 
LEU CA    CB     sing N N 324 
LEU CA    HA     sing N N 325 
LEU C     O      doub N N 326 
LEU C     OXT    sing N N 327 
LEU CB    CG     sing N N 328 
LEU CB    HB2    sing N N 329 
LEU CB    HB3    sing N N 330 
LEU CG    CD1    sing N N 331 
LEU CG    CD2    sing N N 332 
LEU CG    HG     sing N N 333 
LEU CD1   HD11   sing N N 334 
LEU CD1   HD12   sing N N 335 
LEU CD1   HD13   sing N N 336 
LEU CD2   HD21   sing N N 337 
LEU CD2   HD22   sing N N 338 
LEU CD2   HD23   sing N N 339 
LEU OXT   HXT    sing N N 340 
LYS N     CA     sing N N 341 
LYS N     H      sing N N 342 
LYS N     H2     sing N N 343 
LYS CA    C      sing N N 344 
LYS CA    CB     sing N N 345 
LYS CA    HA     sing N N 346 
LYS C     O      doub N N 347 
LYS C     OXT    sing N N 348 
LYS CB    CG     sing N N 349 
LYS CB    HB2    sing N N 350 
LYS CB    HB3    sing N N 351 
LYS CG    CD     sing N N 352 
LYS CG    HG2    sing N N 353 
LYS CG    HG3    sing N N 354 
LYS CD    CE     sing N N 355 
LYS CD    HD2    sing N N 356 
LYS CD    HD3    sing N N 357 
LYS CE    NZ     sing N N 358 
LYS CE    HE2    sing N N 359 
LYS CE    HE3    sing N N 360 
LYS NZ    HZ1    sing N N 361 
LYS NZ    HZ2    sing N N 362 
LYS NZ    HZ3    sing N N 363 
LYS OXT   HXT    sing N N 364 
MET N     CA     sing N N 365 
MET N     H      sing N N 366 
MET N     H2     sing N N 367 
MET CA    C      sing N N 368 
MET CA    CB     sing N N 369 
MET CA    HA     sing N N 370 
MET C     O      doub N N 371 
MET C     OXT    sing N N 372 
MET CB    CG     sing N N 373 
MET CB    HB2    sing N N 374 
MET CB    HB3    sing N N 375 
MET CG    SD     sing N N 376 
MET CG    HG2    sing N N 377 
MET CG    HG3    sing N N 378 
MET SD    CE     sing N N 379 
MET CE    HE1    sing N N 380 
MET CE    HE2    sing N N 381 
MET CE    HE3    sing N N 382 
MET OXT   HXT    sing N N 383 
PHE N     CA     sing N N 384 
PHE N     H      sing N N 385 
PHE N     H2     sing N N 386 
PHE CA    C      sing N N 387 
PHE CA    CB     sing N N 388 
PHE CA    HA     sing N N 389 
PHE C     O      doub N N 390 
PHE C     OXT    sing N N 391 
PHE CB    CG     sing N N 392 
PHE CB    HB2    sing N N 393 
PHE CB    HB3    sing N N 394 
PHE CG    CD1    doub Y N 395 
PHE CG    CD2    sing Y N 396 
PHE CD1   CE1    sing Y N 397 
PHE CD1   HD1    sing N N 398 
PHE CD2   CE2    doub Y N 399 
PHE CD2   HD2    sing N N 400 
PHE CE1   CZ     doub Y N 401 
PHE CE1   HE1    sing N N 402 
PHE CE2   CZ     sing Y N 403 
PHE CE2   HE2    sing N N 404 
PHE CZ    HZ     sing N N 405 
PHE OXT   HXT    sing N N 406 
PRO N     CA     sing N N 407 
PRO N     CD     sing N N 408 
PRO N     H      sing N N 409 
PRO CA    C      sing N N 410 
PRO CA    CB     sing N N 411 
PRO CA    HA     sing N N 412 
PRO C     O      doub N N 413 
PRO C     OXT    sing N N 414 
PRO CB    CG     sing N N 415 
PRO CB    HB2    sing N N 416 
PRO CB    HB3    sing N N 417 
PRO CG    CD     sing N N 418 
PRO CG    HG2    sing N N 419 
PRO CG    HG3    sing N N 420 
PRO CD    HD2    sing N N 421 
PRO CD    HD3    sing N N 422 
PRO OXT   HXT    sing N N 423 
SER N     CA     sing N N 424 
SER N     H      sing N N 425 
SER N     H2     sing N N 426 
SER CA    C      sing N N 427 
SER CA    CB     sing N N 428 
SER CA    HA     sing N N 429 
SER C     O      doub N N 430 
SER C     OXT    sing N N 431 
SER CB    OG     sing N N 432 
SER CB    HB2    sing N N 433 
SER CB    HB3    sing N N 434 
SER OG    HG     sing N N 435 
SER OXT   HXT    sing N N 436 
THR N     CA     sing N N 437 
THR N     H      sing N N 438 
THR N     H2     sing N N 439 
THR CA    C      sing N N 440 
THR CA    CB     sing N N 441 
THR CA    HA     sing N N 442 
THR C     O      doub N N 443 
THR C     OXT    sing N N 444 
THR CB    OG1    sing N N 445 
THR CB    CG2    sing N N 446 
THR CB    HB     sing N N 447 
THR OG1   HG1    sing N N 448 
THR CG2   HG21   sing N N 449 
THR CG2   HG22   sing N N 450 
THR CG2   HG23   sing N N 451 
THR OXT   HXT    sing N N 452 
TRP N     CA     sing N N 453 
TRP N     H      sing N N 454 
TRP N     H2     sing N N 455 
TRP CA    C      sing N N 456 
TRP CA    CB     sing N N 457 
TRP CA    HA     sing N N 458 
TRP C     O      doub N N 459 
TRP C     OXT    sing N N 460 
TRP CB    CG     sing N N 461 
TRP CB    HB2    sing N N 462 
TRP CB    HB3    sing N N 463 
TRP CG    CD1    doub Y N 464 
TRP CG    CD2    sing Y N 465 
TRP CD1   NE1    sing Y N 466 
TRP CD1   HD1    sing N N 467 
TRP CD2   CE2    doub Y N 468 
TRP CD2   CE3    sing Y N 469 
TRP NE1   CE2    sing Y N 470 
TRP NE1   HE1    sing N N 471 
TRP CE2   CZ2    sing Y N 472 
TRP CE3   CZ3    doub Y N 473 
TRP CE3   HE3    sing N N 474 
TRP CZ2   CH2    doub Y N 475 
TRP CZ2   HZ2    sing N N 476 
TRP CZ3   CH2    sing Y N 477 
TRP CZ3   HZ3    sing N N 478 
TRP CH2   HH2    sing N N 479 
TRP OXT   HXT    sing N N 480 
TYR N     CA     sing N N 481 
TYR N     H      sing N N 482 
TYR N     H2     sing N N 483 
TYR CA    C      sing N N 484 
TYR CA    CB     sing N N 485 
TYR CA    HA     sing N N 486 
TYR C     O      doub N N 487 
TYR C     OXT    sing N N 488 
TYR CB    CG     sing N N 489 
TYR CB    HB2    sing N N 490 
TYR CB    HB3    sing N N 491 
TYR CG    CD1    doub Y N 492 
TYR CG    CD2    sing Y N 493 
TYR CD1   CE1    sing Y N 494 
TYR CD1   HD1    sing N N 495 
TYR CD2   CE2    doub Y N 496 
TYR CD2   HD2    sing N N 497 
TYR CE1   CZ     doub Y N 498 
TYR CE1   HE1    sing N N 499 
TYR CE2   CZ     sing Y N 500 
TYR CE2   HE2    sing N N 501 
TYR CZ    OH     sing N N 502 
TYR OH    HH     sing N N 503 
TYR OXT   HXT    sing N N 504 
VAL N     CA     sing N N 505 
VAL N     H      sing N N 506 
VAL N     H2     sing N N 507 
VAL CA    C      sing N N 508 
VAL CA    CB     sing N N 509 
VAL CA    HA     sing N N 510 
VAL C     O      doub N N 511 
VAL C     OXT    sing N N 512 
VAL CB    CG1    sing N N 513 
VAL CB    CG2    sing N N 514 
VAL CB    HB     sing N N 515 
VAL CG1   HG11   sing N N 516 
VAL CG1   HG12   sing N N 517 
VAL CG1   HG13   sing N N 518 
VAL CG2   HG21   sing N N 519 
VAL CG2   HG22   sing N N 520 
VAL CG2   HG23   sing N N 521 
VAL OXT   HXT    sing N N 522 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-06-28 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9CG4 
_em_admin.last_update        2025-02-19 
_em_admin.map_release_date   2025-02-19 
_em_admin.title              'Cryo-EM structure of FAN1, PCNA and DNA substrate with (CAG)2 extrusion in intermediate state' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING ONLY' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          469008 
_em_entity_assembly_recombinant.organism             'Escherichia coli BL21(DE3)' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? 1 ? ? ? 
OTHER                      ? 8  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 9  1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 10 1 ? ? ? ? 
CLASSIFICATION             ? 11 1 ? ? ? ? 
RECONSTRUCTION             ? 12 1 ? ? ? ? 
'MODEL REFINEMENT'         ? 13 ? 1 ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
9CG4 'double helix'        
9CG4 'b-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 E DC 1  1_555 F DG 20 1_555 -1.107 -0.143 -0.526 -3.302  3.061   3.726   1  A_DC1:DG40_F  A 1  ? F 40 ? 19 1 
1 E DG 2  1_555 F DC 19 1_555 -0.659 0.841  -1.173 -0.588  -0.669  -23.435 2  A_DG2:DC39_F  A 2  ? F 39 ? ?  ? 
1 E DA 3  1_555 F DT 18 1_555 -0.449 0.760  -1.468 0.663   -2.008  -23.558 3  A_DA3:DT38_F  A 3  ? F 38 ? ?  ? 
1 E DA 4  1_555 F DT 17 1_555 1.377  0.429  -1.618 4.458   -4.350  -27.275 4  A_DA4:DT37_F  A 4  ? F 37 ? ?  ? 
1 E DT 5  1_555 F DA 16 1_555 -0.404 -0.562 -1.603 7.860   -7.917  -13.849 5  A_DT5:DA36_F  A 5  ? F 36 ? 20 1 
1 E DT 6  1_555 F DA 15 1_555 -0.346 -0.520 -0.664 3.670   -12.067 -6.383  6  A_DT6:DA35_F  A 6  ? F 35 ? 20 1 
1 E DT 7  1_555 F DA 14 1_555 0.001  -0.649 -0.036 -2.233  -11.904 -2.285  7  A_DT7:DA34_F  A 7  ? F 34 ? 20 1 
1 E DC 8  1_555 F DG 13 1_555 -0.022 -0.652 0.316  -8.311  -7.847  -1.653  8  A_DC8:DG33_F  A 8  ? F 33 ? 19 1 
1 E DT 9  1_555 F DA 12 1_555 -0.081 -0.699 0.679  -9.441  -2.378  -2.577  9  A_DT9:DA32_F  A 9  ? F 32 ? 20 1 
1 E DA 10 1_555 F DT 11 1_555 0.327  -0.478 -0.870 -7.651  2.975   -16.240 10 A_DA10:DT31_F A 10 ? F 31 ? 20 1 
1 E DG 11 1_555 F DC 10 1_555 -0.340 -0.765 -1.234 -3.135  4.926   -9.105  11 A_DG11:DC30_F A 11 ? F 30 ? 19 1 
1 E DA 12 1_555 F DT 9  1_555 0.486  -0.768 -1.291 1.336   2.069   -13.023 12 A_DA12:DT29_F A 12 ? F 29 ? 20 1 
1 E DC 13 1_555 F DG 8  1_555 0.190  -0.875 -1.225 3.195   -0.605  -9.161  13 A_DC13:DG28_F A 13 ? F 28 ? 19 1 
1 E DT 14 1_555 F DA 7  1_555 0.207  -0.640 -0.143 1.607   -4.376  -7.872  14 A_DT14:DA27_F A 14 ? F 27 ? 20 1 
1 E DC 15 1_555 F DG 6  1_555 0.163  -0.581 -0.083 2.863   -0.159  -4.670  15 A_DC15:DG26_F A 15 ? F 26 ? 19 1 
1 E DG 16 1_555 F DC 5  1_555 -1.020 -0.234 -0.823 -3.655  -9.348  -11.974 16 A_DG16:DC25_F A 16 ? F 25 ? 19 1 
1 E DA 17 1_555 F DT 4  1_555 1.043  0.330  -1.184 -12.316 -2.012  -17.455 17 A_DA17:DT24_F A 17 ? F 24 ? 20 1 
1 E DG 18 1_555 F DC 3  1_555 -0.354 0.707  -0.312 4.128   14.937  0.789   18 A_DG18:DC23_F A 18 ? F 23 ? ?  1 
1 E DA 19 1_555 F DT 2  1_555 0.523  0.134  -0.594 12.587  18.907  -5.737  19 A_DA19:DT22_F A 19 ? F 22 ? 20 1 
1 E DT 20 1_555 F DA 1  1_555 1.246  0.227  -1.647 27.932  13.580  3.867   20 A_DT20:DA21_F A 20 ? F 21 ? ?  1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 E DC 1  1_555 F DG 20 1_555 E DG 2  1_555 F DC 19 1_555 -2.092 0.824  3.423 -0.290 -1.245 35.439 1.543  3.391  3.409 -2.045 
0.476  35.462 1  AA_DC1DG2:DC39DG40_FF   A 1  ? F 40 ? A 2  ? F 39 ? 
1 E DG 2  1_555 F DC 19 1_555 E DA 3  1_555 F DT 18 1_555 -0.095 0.012  3.242 -0.619 1.770  35.660 -0.234 0.066  3.240 2.888  
1.010  35.708 2  AA_DG2DA3:DT38DC39_FF   A 2  ? F 39 ? A 3  ? F 38 ? 
1 E DA 3  1_555 F DT 18 1_555 E DA 4  1_555 F DT 17 1_555 -0.532 -0.571 3.170 -0.695 1.972  38.900 -1.087 0.716  3.147 2.958  
1.042  38.954 3  AA_DA3DA4:DT37DT38_FF   A 3  ? F 38 ? A 4  ? F 37 ? 
1 E DA 4  1_555 F DT 17 1_555 E DT 5  1_555 F DA 16 1_555 1.158  -0.954 3.089 0.851  1.288  27.351 -2.315 -2.246 3.075 2.722  
-1.797 27.394 4  AA_DA4DT5:DA36DT37_FF   A 4  ? F 37 ? A 5  ? F 36 ? 
1 E DT 5  1_555 F DA 16 1_555 E DT 6  1_555 F DA 15 1_555 1.045  0.527  3.508 0.720  1.134  39.119 0.641  -1.467 3.540 1.693  
-1.076 39.141 5  AA_DT5DT6:DA35DA36_FF   A 5  ? F 36 ? A 6  ? F 35 ? 
1 E DT 6  1_555 F DA 15 1_555 E DT 7  1_555 F DA 14 1_555 0.747  -0.024 3.443 0.281  1.409  40.129 -0.204 -1.055 3.445 2.052  
-0.409 40.154 6  AA_DT6DT7:DA34DA35_FF   A 6  ? F 35 ? A 7  ? F 34 ? 
1 E DT 7  1_555 F DA 14 1_555 E DC 8  1_555 F DG 13 1_555 0.479  0.340  3.383 0.296  0.423  43.547 0.417  -0.616 3.389 0.570  
-0.398 43.550 7  AA_DT7DC8:DG33DA34_FF   A 7  ? F 34 ? A 8  ? F 33 ? 
1 E DC 8  1_555 F DG 13 1_555 E DT 9  1_555 F DA 12 1_555 0.191  -0.218 3.361 0.059  0.754  35.886 -0.464 -0.301 3.356 1.224  
-0.096 35.893 8  AA_DC8DT9:DA32DG33_FF   A 8  ? F 33 ? A 9  ? F 32 ? 
1 E DT 9  1_555 F DA 12 1_555 E DA 10 1_555 F DT 11 1_555 -1.104 0.726  3.781 0.818  -0.338 44.086 1.004  1.560  3.755 -0.450 
-1.090 44.095 9  AA_DT9DA10:DT31DA32_FF  A 9  ? F 32 ? A 10 ? F 31 ? 
1 E DA 10 1_555 F DT 11 1_555 E DG 11 1_555 F DC 10 1_555 0.228  -0.685 3.533 -1.412 0.410  28.730 -1.477 -0.800 3.508 0.825  
2.843  28.766 10 AA_DA10DG11:DC30DT31_FF A 10 ? F 31 ? A 11 ? F 30 ? 
1 E DG 11 1_555 F DC 10 1_555 E DA 12 1_555 F DT 9  1_555 -0.317 -0.002 3.278 -0.665 0.271  39.989 -0.034 0.388  3.283 0.396  
0.973  39.995 11 AA_DG11DA12:DT29DC30_FF A 11 ? F 30 ? A 12 ? F 29 ? 
1 E DA 12 1_555 F DT 9  1_555 E DC 13 1_555 F DG 8  1_555 0.044  -1.106 3.222 -1.259 -0.366 36.948 -1.695 -0.236 3.230 -0.578 
1.985  36.971 12 AA_DA12DC13:DG28DT29_FF A 12 ? F 29 ? A 13 ? F 28 ? 
1 E DC 13 1_555 F DG 8  1_555 E DT 14 1_555 F DA 7  1_555 0.311  -0.024 3.627 -0.106 1.061  38.707 -0.180 -0.484 3.624 1.601  
0.160  38.721 13 AA_DC13DT14:DA27DG28_FF A 13 ? F 28 ? A 14 ? F 27 ? 
1 E DT 14 1_555 F DA 7  1_555 E DC 15 1_555 F DG 6  1_555 0.189  -0.543 3.123 0.395  0.845  34.413 -1.042 -0.261 3.111 1.428  
-0.667 34.425 14 AA_DT14DC15:DG26DA27_FF A 14 ? F 27 ? A 15 ? F 26 ? 
1 E DC 15 1_555 F DG 6  1_555 E DG 16 1_555 F DC 5  1_555 -0.830 0.381  3.799 -1.874 -5.618 34.332 1.628  1.056  3.731 -9.430 
3.146  34.824 15 AA_DC15DG16:DC25DG26_FF A 15 ? F 26 ? A 16 ? F 25 ? 
1 E DG 16 1_555 F DC 5  1_555 E DA 17 1_555 F DT 4  1_555 -0.844 -0.938 3.454 -0.982 -0.193 40.693 -1.326 1.099  3.477 -0.278 
1.412  40.705 16 AA_DG16DA17:DT24DC25_FF A 16 ? F 25 ? A 17 ? F 24 ? 
1 E DA 17 1_555 F DT 4  1_555 E DG 18 1_555 F DC 3  1_555 0.272  -0.788 2.776 -9.926 -2.257 24.615 -1.211 -2.792 2.537 -5.028 
22.113 26.607 17 AA_DA17DG18:DC23DT24_FF A 17 ? F 24 ? A 18 ? F 23 ? 
1 E DG 18 1_555 F DC 3  1_555 E DA 19 1_555 F DT 2  1_555 -1.278 -1.407 3.070 -0.354 4.417  32.226 -3.217 2.225  2.870 7.911  
0.634  32.521 18 AA_DG18DA19:DT22DC23_FF A 18 ? F 23 ? A 19 ? F 22 ? 
1 E DA 19 1_555 F DT 2  1_555 E DT 20 1_555 F DA 1  1_555 0.258  -1.190 3.211 3.037  2.049  29.076 -2.782 0.129  3.132 4.062  
-6.019 29.301 19 AA_DA19DT20:DA21DT22_FF A 19 ? F 22 ? A 20 ? F 21 ? 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9CG4 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N     . MET A 1 1   ? 96.508  151.233 125.531 1.00 53.55  ?  1   MET B N     1 
ATOM 2    C CA    . MET A 1 1   ? 97.429  150.164 125.162 1.00 53.55  ?  1   MET B CA    1 
ATOM 3    C C     . MET A 1 1   ? 98.171  150.560 123.890 1.00 53.55  ?  1   MET B C     1 
ATOM 4    O O     . MET A 1 1   ? 97.595  151.157 122.983 1.00 53.55  ?  1   MET B O     1 
ATOM 5    C CB    . MET A 1 1   ? 96.663  148.829 125.044 1.00 53.55  ?  1   MET B CB    1 
ATOM 6    C CG    . MET A 1 1   ? 95.953  148.450 123.731 1.00 53.55  ?  1   MET B CG    1 
ATOM 7    S SD    . MET A 1 1   ? 96.873  148.308 122.181 1.00 53.55  ?  1   MET B SD    1 
ATOM 8    C CE    . MET A 1 1   ? 98.102  147.092 122.630 1.00 53.55  ?  1   MET B CE    1 
ATOM 9    N N     . PHE A 1 2   ? 99.465  150.254 123.851 1.00 42.39  ?  2   PHE B N     1 
ATOM 10   C CA    . PHE A 1 2   ? 100.361 150.694 122.789 1.00 42.39  ?  2   PHE B CA    1 
ATOM 11   C C     . PHE A 1 2   ? 100.725 149.512 121.901 1.00 42.39  ?  2   PHE B C     1 
ATOM 12   O O     . PHE A 1 2   ? 101.164 148.470 122.396 1.00 42.39  ?  2   PHE B O     1 
ATOM 13   C CB    . PHE A 1 2   ? 101.619 151.335 123.383 1.00 42.39  ?  2   PHE B CB    1 
ATOM 14   C CG    . PHE A 1 2   ? 102.787 151.402 122.435 1.00 42.39  ?  2   PHE B CG    1 
ATOM 15   C CD1   . PHE A 1 2   ? 102.664 151.986 121.187 1.00 42.39  ?  2   PHE B CD1   1 
ATOM 16   C CD2   . PHE A 1 2   ? 104.018 150.893 122.808 1.00 42.39  ?  2   PHE B CD2   1 
ATOM 17   C CE1   . PHE A 1 2   ? 103.743 152.044 120.327 1.00 42.39  ?  2   PHE B CE1   1 
ATOM 18   C CE2   . PHE A 1 2   ? 105.099 150.951 121.954 1.00 42.39  ?  2   PHE B CE2   1 
ATOM 19   C CZ    . PHE A 1 2   ? 104.961 151.526 120.712 1.00 42.39  ?  2   PHE B CZ    1 
ATOM 20   N N     . GLU A 1 3   ? 100.544 149.682 120.593 1.00 40.07  ?  3   GLU B N     1 
ATOM 21   C CA    . GLU A 1 3   ? 100.853 148.648 119.615 1.00 40.07  ?  3   GLU B CA    1 
ATOM 22   C C     . GLU A 1 3   ? 101.428 149.296 118.367 1.00 40.07  ?  3   GLU B C     1 
ATOM 23   O O     . GLU A 1 3   ? 100.792 150.170 117.771 1.00 40.07  ?  3   GLU B O     1 
ATOM 24   C CB    . GLU A 1 3   ? 99.608  147.838 119.252 1.00 40.07  ?  3   GLU B CB    1 
ATOM 25   C CG    . GLU A 1 3   ? 99.729  147.087 117.941 1.00 40.07  ?  3   GLU B CG    1 
ATOM 26   C CD    . GLU A 1 3   ? 98.381  146.683 117.383 1.00 40.07  ?  3   GLU B CD    1 
ATOM 27   O OE1   . GLU A 1 3   ? 97.355  147.113 117.949 1.00 40.07  ?  3   GLU B OE1   1 
ATOM 28   O OE2   . GLU A 1 3   ? 98.347  145.946 116.376 1.00 40.07  -1 3   GLU B OE2   1 
ATOM 29   N N     . ALA A 1 4   ? 102.622 148.863 117.971 1.00 35.24  ?  4   ALA B N     1 
ATOM 30   C CA    . ALA A 1 4   ? 103.287 149.374 116.781 1.00 35.24  ?  4   ALA B CA    1 
ATOM 31   C C     . ALA A 1 4   ? 103.691 148.206 115.899 1.00 35.24  ?  4   ALA B C     1 
ATOM 32   O O     . ALA A 1 4   ? 104.261 147.227 116.388 1.00 35.24  ?  4   ALA B O     1 
ATOM 33   C CB    . ALA A 1 4   ? 104.514 150.211 117.146 1.00 35.24  ?  4   ALA B CB    1 
ATOM 34   N N     . ARG A 1 5   ? 103.400 148.310 114.605 1.00 35.40  ?  5   ARG B N     1 
ATOM 35   C CA    . ARG A 1 5   ? 103.691 147.253 113.643 1.00 35.40  ?  5   ARG B CA    1 
ATOM 36   C C     . ARG A 1 5   ? 104.635 147.815 112.589 1.00 35.40  ?  5   ARG B C     1 
ATOM 37   O O     . ARG A 1 5   ? 104.221 148.609 111.738 1.00 35.40  ?  5   ARG B O     1 
ATOM 38   C CB    . ARG A 1 5   ? 102.407 146.724 113.008 1.00 35.40  ?  5   ARG B CB    1 
ATOM 39   C CG    . ARG A 1 5   ? 102.630 145.758 111.863 1.00 35.40  ?  5   ARG B CG    1 
ATOM 40   C CD    . ARG A 1 5   ? 101.325 145.110 111.438 1.00 35.40  ?  5   ARG B CD    1 
ATOM 41   N NE    . ARG A 1 5   ? 101.410 144.550 110.096 1.00 35.40  ?  5   ARG B NE    1 
ATOM 42   C CZ    . ARG A 1 5   ? 101.925 143.361 109.815 1.00 35.40  ?  5   ARG B CZ    1 
ATOM 43   N NH1   . ARG A 1 5   ? 102.399 142.572 110.765 1.00 35.40  1  5   ARG B NH1   1 
ATOM 44   N NH2   . ARG A 1 5   ? 101.964 142.953 108.550 1.00 35.40  ?  5   ARG B NH2   1 
ATOM 45   N N     . LEU A 1 6   ? 105.895 147.399 112.642 1.00 36.32  ?  6   LEU B N     1 
ATOM 46   C CA    . LEU A 1 6   ? 106.929 147.877 111.734 1.00 36.32  ?  6   LEU B CA    1 
ATOM 47   C C     . LEU A 1 6   ? 107.281 146.761 110.762 1.00 36.32  ?  6   LEU B C     1 
ATOM 48   O O     . LEU A 1 6   ? 107.656 145.663 111.184 1.00 36.32  ?  6   LEU B O     1 
ATOM 49   C CB    . LEU A 1 6   ? 108.164 148.329 112.511 1.00 36.32  ?  6   LEU B CB    1 
ATOM 50   C CG    . LEU A 1 6   ? 109.449 148.544 111.716 1.00 36.32  ?  6   LEU B CG    1 
ATOM 51   C CD1   . LEU A 1 6   ? 109.227 149.544 110.595 1.00 36.32  ?  6   LEU B CD1   1 
ATOM 52   C CD2   . LEU A 1 6   ? 110.555 149.014 112.639 1.00 36.32  ?  6   LEU B CD2   1 
ATOM 53   N N     . VAL A 1 7   ? 107.159 147.044 109.465 1.00 39.37  ?  7   VAL B N     1 
ATOM 54   C CA    . VAL A 1 7   ? 107.406 146.019 108.456 1.00 39.37  ?  7   VAL B CA    1 
ATOM 55   C C     . VAL A 1 7   ? 108.890 145.684 108.373 1.00 39.37  ?  7   VAL B C     1 
ATOM 56   O O     . VAL A 1 7   ? 109.270 144.514 108.251 1.00 39.37  ?  7   VAL B O     1 
ATOM 57   C CB    . VAL A 1 7   ? 106.849 146.470 107.095 1.00 39.37  ?  7   VAL B CB    1 
ATOM 58   C CG1   . VAL A 1 7   ? 107.215 145.469 106.012 1.00 39.37  ?  7   VAL B CG1   1 
ATOM 59   C CG2   . VAL A 1 7   ? 105.346 146.640 107.178 1.00 39.37  ?  7   VAL B CG2   1 
ATOM 60   N N     . GLN A 1 8   ? 109.751 146.696 108.438 1.00 37.09  ?  8   GLN B N     1 
ATOM 61   C CA    . GLN A 1 8   ? 111.189 146.507 108.252 1.00 37.09  ?  8   GLN B CA    1 
ATOM 62   C C     . GLN A 1 8   ? 111.840 146.290 109.612 1.00 37.09  ?  8   GLN B C     1 
ATOM 63   O O     . GLN A 1 8   ? 112.080 147.242 110.357 1.00 37.09  ?  8   GLN B O     1 
ATOM 64   C CB    . GLN A 1 8   ? 111.795 147.707 107.534 1.00 37.09  ?  8   GLN B CB    1 
ATOM 65   C CG    . GLN A 1 8   ? 111.334 147.870 106.099 1.00 37.09  ?  8   GLN B CG    1 
ATOM 66   C CD    . GLN A 1 8   ? 112.467 147.710 105.108 1.00 37.09  ?  8   GLN B CD    1 
ATOM 67   O OE1   . GLN A 1 8   ? 113.576 148.192 105.334 1.00 37.09  ?  8   GLN B OE1   1 
ATOM 68   N NE2   . GLN A 1 8   ? 112.193 147.032 104.001 1.00 37.09  ?  8   GLN B NE2   1 
ATOM 69   N N     . GLY A 1 9   ? 112.138 145.032 109.937 1.00 34.27  ?  9   GLY B N     1 
ATOM 70   C CA    . GLY A 1 9   ? 112.828 144.740 111.180 1.00 34.27  ?  9   GLY B CA    1 
ATOM 71   C C     . GLY A 1 9   ? 114.300 145.090 111.160 1.00 34.27  ?  9   GLY B C     1 
ATOM 72   O O     . GLY A 1 9   ? 114.902 145.269 112.227 1.00 34.27  ?  9   GLY B O     1 
ATOM 73   N N     . SER A 1 10  ? 114.892 145.197 109.968 1.00 34.45  ?  10  SER B N     1 
ATOM 74   C CA    . SER A 1 10  ? 116.304 145.542 109.871 1.00 34.45  ?  10  SER B CA    1 
ATOM 75   C C     . SER A 1 10  ? 116.585 146.915 110.462 1.00 34.45  ?  10  SER B C     1 
ATOM 76   O O     . SER A 1 10  ? 117.649 147.129 111.053 1.00 34.45  ?  10  SER B O     1 
ATOM 77   C CB    . SER A 1 10  ? 116.757 145.488 108.413 1.00 34.45  ?  10  SER B CB    1 
ATOM 78   O OG    . SER A 1 10  ? 116.103 146.479 107.641 1.00 34.45  ?  10  SER B OG    1 
ATOM 79   N N     . ILE A 1 11  ? 115.647 147.854 110.320 1.00 31.83  ?  11  ILE B N     1 
ATOM 80   C CA    . ILE A 1 11  ? 115.846 149.194 110.864 1.00 31.83  ?  11  ILE B CA    1 
ATOM 81   C C     . ILE A 1 11  ? 115.976 149.139 112.380 1.00 31.83  ?  11  ILE B C     1 
ATOM 82   O O     . ILE A 1 11  ? 116.894 149.727 112.966 1.00 31.83  ?  11  ILE B O     1 
ATOM 83   C CB    . ILE A 1 11  ? 114.698 150.121 110.432 1.00 31.83  ?  11  ILE B CB    1 
ATOM 84   C CG1   . ILE A 1 11  ? 114.778 150.399 108.932 1.00 31.83  ?  11  ILE B CG1   1 
ATOM 85   C CG2   . ILE A 1 11  ? 114.739 151.409 111.224 1.00 31.83  ?  11  ILE B CG2   1 
ATOM 86   C CD1   . ILE A 1 11  ? 113.510 150.975 108.352 1.00 31.83  ?  11  ILE B CD1   1 
ATOM 87   N N     . LEU A 1 12  ? 115.057 148.429 113.039 1.00 30.37  ?  12  LEU B N     1 
ATOM 88   C CA    . LEU A 1 12  ? 115.127 148.309 114.490 1.00 30.37  ?  12  LEU B CA    1 
ATOM 89   C C     . LEU A 1 12  ? 116.369 147.544 114.921 1.00 30.37  ?  12  LEU B C     1 
ATOM 90   O O     . LEU A 1 12  ? 117.001 147.894 115.926 1.00 30.37  ?  12  LEU B O     1 
ATOM 91   C CB    . LEU A 1 12  ? 113.866 147.637 115.027 1.00 30.37  ?  12  LEU B CB    1 
ATOM 92   C CG    . LEU A 1 12  ? 112.840 148.602 115.618 1.00 30.37  ?  12  LEU B CG    1 
ATOM 93   C CD1   . LEU A 1 12  ? 111.559 147.877 115.975 1.00 30.37  ?  12  LEU B CD1   1 
ATOM 94   C CD2   . LEU A 1 12  ? 113.419 149.295 116.835 1.00 30.37  ?  12  LEU B CD2   1 
ATOM 95   N N     . LYS A 1 13  ? 116.736 146.497 114.178 1.00 35.63  ?  13  LYS B N     1 
ATOM 96   C CA    . LYS A 1 13  ? 117.950 145.757 114.507 1.00 35.63  ?  13  LYS B CA    1 
ATOM 97   C C     . LYS A 1 13  ? 119.169 146.669 114.468 1.00 35.63  ?  13  LYS B C     1 
ATOM 98   O O     . LYS A 1 13  ? 119.993 146.668 115.391 1.00 35.63  ?  13  LYS B O     1 
ATOM 99   C CB    . LYS A 1 13  ? 118.127 144.583 113.545 1.00 35.63  ?  13  LYS B CB    1 
ATOM 100  C CG    . LYS A 1 13  ? 117.300 143.360 113.892 1.00 35.63  ?  13  LYS B CG    1 
ATOM 101  C CD    . LYS A 1 13  ? 117.465 142.271 112.846 1.00 35.63  ?  13  LYS B CD    1 
ATOM 102  C CE    . LYS A 1 13  ? 118.899 141.776 112.786 1.00 35.63  ?  13  LYS B CE    1 
ATOM 103  N NZ    . LYS A 1 13  ? 119.186 140.780 113.853 1.00 35.63  1  13  LYS B NZ    1 
ATOM 104  N N     . LYS A 1 14  ? 119.288 147.473 113.409 1.00 34.47  ?  14  LYS B N     1 
ATOM 105  C CA    . LYS A 1 14  ? 120.432 148.367 113.275 1.00 34.47  ?  14  LYS B CA    1 
ATOM 106  C C     . LYS A 1 14  ? 120.427 149.445 114.351 1.00 34.47  ?  14  LYS B C     1 
ATOM 107  O O     . LYS A 1 14  ? 121.482 149.781 114.901 1.00 34.47  ?  14  LYS B O     1 
ATOM 108  C CB    . LYS A 1 14  ? 120.444 148.995 111.883 1.00 34.47  ?  14  LYS B CB    1 
ATOM 109  C CG    . LYS A 1 14  ? 120.750 148.008 110.773 1.00 34.47  ?  14  LYS B CG    1 
ATOM 110  C CD    . LYS A 1 14  ? 120.121 148.441 109.463 1.00 34.47  ?  14  LYS B CD    1 
ATOM 111  C CE    . LYS A 1 14  ? 120.158 147.319 108.442 1.00 34.47  ?  14  LYS B CE    1 
ATOM 112  N NZ    . LYS A 1 14  ? 119.367 147.656 107.229 1.00 34.47  1  14  LYS B NZ    1 
ATOM 113  N N     . VAL A 1 15  ? 119.254 149.998 114.666 1.00 34.98  ?  15  VAL B N     1 
ATOM 114  C CA    . VAL A 1 15  ? 119.175 151.025 115.702 1.00 34.98  ?  15  VAL B CA    1 
ATOM 115  C C     . VAL A 1 15  ? 119.625 150.460 117.043 1.00 34.98  ?  15  VAL B C     1 
ATOM 116  O O     . VAL A 1 15  ? 120.443 151.063 117.753 1.00 34.98  ?  15  VAL B O     1 
ATOM 117  C CB    . VAL A 1 15  ? 117.747 151.594 115.782 1.00 34.98  ?  15  VAL B CB    1 
ATOM 118  C CG1   . VAL A 1 15  ? 117.542 152.322 117.092 1.00 34.98  ?  15  VAL B CG1   1 
ATOM 119  C CG2   . VAL A 1 15  ? 117.480 152.517 114.613 1.00 34.98  ?  15  VAL B CG2   1 
ATOM 120  N N     . LEU A 1 16  ? 119.109 149.283 117.403 1.00 39.18  ?  16  LEU B N     1 
ATOM 121  C CA    . LEU A 1 16  ? 119.463 148.685 118.685 1.00 39.18  ?  16  LEU B CA    1 
ATOM 122  C C     . LEU A 1 16  ? 120.934 148.299 118.731 1.00 39.18  ?  16  LEU B C     1 
ATOM 123  O O     . LEU A 1 16  ? 121.574 148.403 119.783 1.00 39.18  ?  16  LEU B O     1 
ATOM 124  C CB    . LEU A 1 16  ? 118.575 147.475 118.960 1.00 39.18  ?  16  LEU B CB    1 
ATOM 125  C CG    . LEU A 1 16  ? 117.488 147.723 120.003 1.00 39.18  ?  16  LEU B CG    1 
ATOM 126  C CD1   . LEU A 1 16  ? 118.121 147.890 121.366 1.00 39.18  ?  16  LEU B CD1   1 
ATOM 127  C CD2   . LEU A 1 16  ? 116.670 148.949 119.643 1.00 39.18  ?  16  LEU B CD2   1 
ATOM 128  N N     . GLU A 1 17  ? 121.490 147.844 117.605 1.00 44.22  ?  17  GLU B N     1 
ATOM 129  C CA    . GLU A 1 17  ? 122.919 147.560 117.564 1.00 44.22  ?  17  GLU B CA    1 
ATOM 130  C C     . GLU A 1 17  ? 123.733 148.832 117.756 1.00 44.22  ?  17  GLU B C     1 
ATOM 131  O O     . GLU A 1 17  ? 124.763 148.824 118.440 1.00 44.22  ?  17  GLU B O     1 
ATOM 132  C CB    . GLU A 1 17  ? 123.279 146.876 116.245 1.00 44.22  ?  17  GLU B CB    1 
ATOM 133  C CG    . GLU A 1 17  ? 124.628 147.275 115.674 1.00 44.22  ?  17  GLU B CG    1 
ATOM 134  C CD    . GLU A 1 17  ? 124.735 146.999 114.188 1.00 44.22  ?  17  GLU B CD    1 
ATOM 135  O OE1   . GLU A 1 17  ? 124.615 145.821 113.792 1.00 44.22  ?  17  GLU B OE1   1 
ATOM 136  O OE2   . GLU A 1 17  ? 124.941 147.959 113.416 1.00 44.22  -1 17  GLU B OE2   1 
ATOM 137  N N     . ALA A 1 18  ? 123.284 149.939 117.162 1.00 41.29  ?  18  ALA B N     1 
ATOM 138  C CA    . ALA A 1 18  ? 123.996 151.203 117.310 1.00 41.29  ?  18  ALA B CA    1 
ATOM 139  C C     . ALA A 1 18  ? 123.961 151.701 118.750 1.00 41.29  ?  18  ALA B C     1 
ATOM 140  O O     . ALA A 1 18  ? 124.958 152.232 119.251 1.00 41.29  ?  18  ALA B O     1 
ATOM 141  C CB    . ALA A 1 18  ? 123.407 152.250 116.368 1.00 41.29  ?  18  ALA B CB    1 
ATOM 142  N N     . LEU A 1 19  ? 122.827 151.546 119.428 1.00 42.26  ?  19  LEU B N     1 
ATOM 143  C CA    . LEU A 1 19  ? 122.674 152.079 120.777 1.00 42.26  ?  19  LEU B CA    1 
ATOM 144  C C     . LEU A 1 19  ? 123.113 151.114 121.872 1.00 42.26  ?  19  LEU B C     1 
ATOM 145  O O     . LEU A 1 19  ? 123.106 151.496 123.046 1.00 42.26  ?  19  LEU B O     1 
ATOM 146  C CB    . LEU A 1 19  ? 121.219 152.484 121.023 1.00 42.26  ?  19  LEU B CB    1 
ATOM 147  C CG    . LEU A 1 19  ? 120.685 153.646 120.192 1.00 42.26  ?  19  LEU B CG    1 
ATOM 148  C CD1   . LEU A 1 19  ? 119.332 154.083 120.716 1.00 42.26  ?  19  LEU B CD1   1 
ATOM 149  C CD2   . LEU A 1 19  ? 121.665 154.800 120.207 1.00 42.26  ?  19  LEU B CD2   1 
ATOM 150  N N     . LYS A 1 20  ? 123.494 149.882 121.531 1.00 50.09  ?  20  LYS B N     1 
ATOM 151  C CA    . LYS A 1 20  ? 123.748 148.885 122.566 1.00 50.09  ?  20  LYS B CA    1 
ATOM 152  C C     . LYS A 1 20  ? 125.066 149.114 123.295 1.00 50.09  ?  20  LYS B C     1 
ATOM 153  O O     . LYS A 1 20  ? 125.186 148.748 124.469 1.00 50.09  ?  20  LYS B O     1 
ATOM 154  C CB    . LYS A 1 20  ? 123.719 147.477 121.967 1.00 50.09  ?  20  LYS B CB    1 
ATOM 155  C CG    . LYS A 1 20  ? 124.995 147.061 121.259 1.00 50.09  ?  20  LYS B CG    1 
ATOM 156  C CD    . LYS A 1 20  ? 125.127 145.550 121.208 1.00 50.09  ?  20  LYS B CD    1 
ATOM 157  C CE    . LYS A 1 20  ? 126.580 145.121 121.300 1.00 50.09  ?  20  LYS B CE    1 
ATOM 158  N NZ    . LYS A 1 20  ? 127.443 145.894 120.367 1.00 50.09  1  20  LYS B NZ    1 
ATOM 159  N N     . ASP A 1 21  ? 126.059 149.707 122.636 1.00 52.29  ?  21  ASP B N     1 
ATOM 160  C CA    . ASP A 1 21  ? 127.380 149.880 123.223 1.00 52.29  ?  21  ASP B CA    1 
ATOM 161  C C     . ASP A 1 21  ? 127.588 151.258 123.832 1.00 52.29  ?  21  ASP B C     1 
ATOM 162  O O     . ASP A 1 21  ? 128.698 151.559 124.282 1.00 52.29  ?  21  ASP B O     1 
ATOM 163  C CB    . ASP A 1 21  ? 128.462 149.614 122.173 1.00 52.29  ?  21  ASP B CB    1 
ATOM 164  C CG    . ASP A 1 21  ? 128.130 150.227 120.831 1.00 52.29  ?  21  ASP B CG    1 
ATOM 165  O OD1   . ASP A 1 21  ? 127.202 151.060 120.772 1.00 52.29  ?  21  ASP B OD1   1 
ATOM 166  O OD2   . ASP A 1 21  ? 128.795 149.875 119.835 1.00 52.29  -1 21  ASP B OD2   1 
ATOM 167  N N     . LEU A 1 22  ? 126.560 152.098 123.859 1.00 50.31  ?  22  LEU B N     1 
ATOM 168  C CA    . LEU A 1 22  ? 126.676 153.444 124.399 1.00 50.31  ?  22  LEU B CA    1 
ATOM 169  C C     . LEU A 1 22  ? 125.683 153.748 125.508 1.00 50.31  ?  22  LEU B C     1 
ATOM 170  O O     . LEU A 1 22  ? 126.003 154.534 126.402 1.00 50.31  ?  22  LEU B O     1 
ATOM 171  C CB    . LEU A 1 22  ? 126.498 154.481 123.279 1.00 50.31  ?  22  LEU B CB    1 
ATOM 172  C CG    . LEU A 1 22  ? 127.043 155.881 123.549 1.00 50.31  ?  22  LEU B CG    1 
ATOM 173  C CD1   . LEU A 1 22  ? 128.549 155.837 123.730 1.00 50.31  ?  22  LEU B CD1   1 
ATOM 174  C CD2   . LEU A 1 22  ? 126.666 156.818 122.420 1.00 50.31  ?  22  LEU B CD2   1 
ATOM 175  N N     . ILE A 1 23  ? 124.495 153.152 125.478 1.00 53.34  ?  23  ILE B N     1 
ATOM 176  C CA    . ILE A 1 23  ? 123.453 153.398 126.466 1.00 53.34  ?  23  ILE B CA    1 
ATOM 177  C C     . ILE A 1 23  ? 122.969 152.056 126.992 1.00 53.34  ?  23  ILE B C     1 
ATOM 178  O O     . ILE A 1 23  ? 122.743 151.126 126.210 1.00 53.34  ?  23  ILE B O     1 
ATOM 179  C CB    . ILE A 1 23  ? 122.283 154.200 125.868 1.00 53.34  ?  23  ILE B CB    1 
ATOM 180  C CG1   . ILE A 1 23  ? 122.757 155.580 125.424 1.00 53.34  ?  23  ILE B CG1   1 
ATOM 181  C CG2   . ILE A 1 23  ? 121.152 154.332 126.868 1.00 53.34  ?  23  ILE B CG2   1 
ATOM 182  C CD1   . ILE A 1 23  ? 121.803 156.261 124.488 1.00 53.34  ?  23  ILE B CD1   1 
ATOM 183  N N     . ASN A 1 24  ? 122.816 151.953 128.310 1.00 57.23  ?  24  ASN B N     1 
ATOM 184  C CA    . ASN A 1 24  ? 122.333 150.728 128.933 1.00 57.23  ?  24  ASN B CA    1 
ATOM 185  C C     . ASN A 1 24  ? 120.881 150.821 129.382 1.00 57.23  ?  24  ASN B C     1 
ATOM 186  O O     . ASN A 1 24  ? 120.154 149.826 129.312 1.00 57.23  ?  24  ASN B O     1 
ATOM 187  C CB    . ASN A 1 24  ? 123.218 150.359 130.125 1.00 57.23  ?  24  ASN B CB    1 
ATOM 188  C CG    . ASN A 1 24  ? 124.397 149.498 129.725 1.00 57.23  ?  24  ASN B CG    1 
ATOM 189  O OD1   . ASN A 1 24  ? 124.833 149.521 128.575 1.00 57.23  ?  24  ASN B OD1   1 
ATOM 190  N ND2   . ASN A 1 24  ? 124.918 148.731 130.674 1.00 57.23  ?  24  ASN B ND2   1 
ATOM 191  N N     . GLU A 1 25  ? 120.439 151.987 129.844 1.00 62.32  ?  25  GLU B N     1 
ATOM 192  C CA    . GLU A 1 25  ? 119.044 152.221 130.191 1.00 62.32  ?  25  GLU B CA    1 
ATOM 193  C C     . GLU A 1 25  ? 118.560 153.477 129.485 1.00 62.32  ?  25  GLU B C     1 
ATOM 194  O O     . GLU A 1 25  ? 119.262 154.492 129.467 1.00 62.32  ?  25  GLU B O     1 
ATOM 195  C CB    . GLU A 1 25  ? 118.857 152.363 131.704 1.00 62.32  ?  25  GLU B CB    1 
ATOM 196  C CG    . GLU A 1 25  ? 118.983 151.064 132.476 1.00 62.32  ?  25  GLU B CG    1 
ATOM 197  C CD    . GLU A 1 25  ? 120.359 150.879 133.078 1.00 62.32  ?  25  GLU B CD    1 
ATOM 198  O OE1   . GLU A 1 25  ? 121.343 151.339 132.463 1.00 62.32  ?  25  GLU B OE1   1 
ATOM 199  O OE2   . GLU A 1 25  ? 120.458 150.277 134.168 1.00 62.32  -1 25  GLU B OE2   1 
ATOM 200  N N     . ALA A 1 26  ? 117.359 153.410 128.918 1.00 48.90  ?  26  ALA B N     1 
ATOM 201  C CA    . ALA A 1 26  ? 116.781 154.538 128.206 1.00 48.90  ?  26  ALA B CA    1 
ATOM 202  C C     . ALA A 1 26  ? 115.324 154.696 128.608 1.00 48.90  ?  26  ALA B C     1 
ATOM 203  O O     . ALA A 1 26  ? 114.673 153.739 129.032 1.00 48.90  ?  26  ALA B O     1 
ATOM 204  C CB    . ALA A 1 26  ? 116.890 154.366 126.687 1.00 48.90  ?  26  ALA B CB    1 
ATOM 205  N N     . CYS A 1 27  ? 114.820 155.917 128.467 1.00 44.38  ?  27  CYS B N     1 
ATOM 206  C CA    . CYS A 1 27  ? 113.438 156.252 128.796 1.00 44.38  ?  27  CYS B CA    1 
ATOM 207  C C     . CYS A 1 27  ? 112.682 156.426 127.482 1.00 44.38  ?  27  CYS B C     1 
ATOM 208  O O     . CYS A 1 27  ? 112.659 157.511 126.900 1.00 44.38  ?  27  CYS B O     1 
ATOM 209  C CB    . CYS A 1 27  ? 113.370 157.510 129.657 1.00 44.38  ?  27  CYS B CB    1 
ATOM 210  S SG    . CYS A 1 27  ? 111.906 157.619 130.714 1.00 44.38  ?  27  CYS B SG    1 
ATOM 211  N N     . TRP A 1 28  ? 112.057 155.346 127.020 1.00 40.60  ?  28  TRP B N     1 
ATOM 212  C CA    . TRP A 1 28  ? 111.312 155.372 125.766 1.00 40.60  ?  28  TRP B CA    1 
ATOM 213  C C     . TRP A 1 28  ? 110.045 156.195 125.947 1.00 40.60  ?  28  TRP B C     1 
ATOM 214  O O     . TRP A 1 28  ? 109.046 155.702 126.479 1.00 40.60  ?  28  TRP B O     1 
ATOM 215  C CB    . TRP A 1 28  ? 110.975 153.953 125.321 1.00 40.60  ?  28  TRP B CB    1 
ATOM 216  C CG    . TRP A 1 28  ? 112.161 153.154 124.911 1.00 40.60  ?  28  TRP B CG    1 
ATOM 217  C CD1   . TRP A 1 28  ? 113.113 152.623 125.729 1.00 40.60  ?  28  TRP B CD1   1 
ATOM 218  C CD2   . TRP A 1 28  ? 112.528 152.788 123.578 1.00 40.60  ?  28  TRP B CD2   1 
ATOM 219  N NE1   . TRP A 1 28  ? 114.051 151.949 124.988 1.00 40.60  ?  28  TRP B NE1   1 
ATOM 220  C CE2   . TRP A 1 28  ? 113.715 152.037 123.663 1.00 40.60  ?  28  TRP B CE2   1 
ATOM 221  C CE3   . TRP A 1 28  ? 111.968 153.025 122.321 1.00 40.60  ?  28  TRP B CE3   1 
ATOM 222  C CZ2   . TRP A 1 28  ? 114.352 151.520 122.539 1.00 40.60  ?  28  TRP B CZ2   1 
ATOM 223  C CZ3   . TRP A 1 28  ? 112.602 152.512 121.206 1.00 40.60  ?  28  TRP B CZ3   1 
ATOM 224  C CH2   . TRP A 1 28  ? 113.781 151.768 121.323 1.00 40.60  ?  28  TRP B CH2   1 
ATOM 225  N N     . ASP A 1 29  ? 110.080 157.447 125.508 1.00 35.78  ?  29  ASP B N     1 
ATOM 226  C CA    . ASP A 1 29  ? 108.917 158.319 125.571 1.00 35.78  ?  29  ASP B CA    1 
ATOM 227  C C     . ASP A 1 29  ? 108.051 158.068 124.344 1.00 35.78  ?  29  ASP B C     1 
ATOM 228  O O     . ASP A 1 29  ? 108.458 158.374 123.219 1.00 35.78  ?  29  ASP B O     1 
ATOM 229  C CB    . ASP A 1 29  ? 109.345 159.784 125.641 1.00 35.78  ?  29  ASP B CB    1 
ATOM 230  C CG    . ASP A 1 29  ? 108.188 160.742 125.439 1.00 35.78  ?  29  ASP B CG    1 
ATOM 231  O OD1   . ASP A 1 29  ? 107.054 160.408 125.842 1.00 35.78  ?  29  ASP B OD1   1 
ATOM 232  O OD2   . ASP A 1 29  ? 108.411 161.832 124.872 1.00 35.78  -1 29  ASP B OD2   1 
ATOM 233  N N     . ILE A 1 30  ? 106.861 157.517 124.560 1.00 35.04  ?  30  ILE B N     1 
ATOM 234  C CA    . ILE A 1 30  ? 105.930 157.193 123.486 1.00 35.04  ?  30  ILE B CA    1 
ATOM 235  C C     . ILE A 1 30  ? 104.744 158.139 123.578 1.00 35.04  ?  30  ILE B C     1 
ATOM 236  O O     . ILE A 1 30  ? 104.122 158.264 124.639 1.00 35.04  ?  30  ILE B O     1 
ATOM 237  C CB    . ILE A 1 30  ? 105.469 155.727 123.555 1.00 35.04  ?  30  ILE B CB    1 
ATOM 238  C CG1   . ILE A 1 30  ? 106.516 154.805 122.930 1.00 35.04  ?  30  ILE B CG1   1 
ATOM 239  C CG2   . ILE A 1 30  ? 104.138 155.556 122.848 1.00 35.04  ?  30  ILE B CG2   1 
ATOM 240  C CD1   . ILE A 1 30  ? 107.670 154.474 123.840 1.00 35.04  ?  30  ILE B CD1   1 
ATOM 241  N N     . SER A 1 31  ? 104.436 158.806 122.471 1.00 36.97  ?  31  SER B N     1 
ATOM 242  C CA    . SER A 1 31  ? 103.293 159.703 122.394 1.00 36.97  ?  31  SER B CA    1 
ATOM 243  C C     . SER A 1 31  ? 102.570 159.429 121.083 1.00 36.97  ?  31  SER B C     1 
ATOM 244  O O     . SER A 1 31  ? 102.922 158.511 120.338 1.00 36.97  ?  31  SER B O     1 
ATOM 245  C CB    . SER A 1 31  ? 103.736 161.166 122.512 1.00 36.97  ?  31  SER B CB    1 
ATOM 246  O OG    . SER A 1 31  ? 104.233 161.640 121.273 1.00 36.97  ?  31  SER B OG    1 
ATOM 247  N N     . SER A 1 32  ? 101.548 160.236 120.796 1.00 37.31  ?  32  SER B N     1 
ATOM 248  C CA    . SER A 1 32  ? 100.835 160.086 119.533 1.00 37.31  ?  32  SER B CA    1 
ATOM 249  C C     . SER A 1 32  ? 101.703 160.493 118.350 1.00 37.31  ?  32  SER B C     1 
ATOM 250  O O     . SER A 1 32  ? 101.479 160.022 117.229 1.00 37.31  ?  32  SER B O     1 
ATOM 251  C CB    . SER A 1 32  ? 99.548  160.908 119.552 1.00 37.31  ?  32  SER B CB    1 
ATOM 252  O OG    . SER A 1 32  ? 99.064  161.120 118.238 1.00 37.31  ?  32  SER B OG    1 
ATOM 253  N N     . SER A 1 33  ? 102.685 161.369 118.574 1.00 37.03  ?  33  SER B N     1 
ATOM 254  C CA    . SER A 1 33  ? 103.586 161.762 117.496 1.00 37.03  ?  33  SER B CA    1 
ATOM 255  C C     . SER A 1 33  ? 104.430 160.585 117.023 1.00 37.03  ?  33  SER B C     1 
ATOM 256  O O     . SER A 1 33  ? 104.628 160.401 115.817 1.00 37.03  ?  33  SER B O     1 
ATOM 257  C CB    . SER A 1 33  ? 104.483 162.909 117.954 1.00 37.03  ?  33  SER B CB    1 
ATOM 258  O OG    . SER A 1 33  ? 105.503 162.438 118.816 1.00 37.03  ?  33  SER B OG    1 
ATOM 259  N N     . GLY A 1 34  ? 104.933 159.790 117.948 1.00 33.62  ?  34  GLY B N     1 
ATOM 260  C CA    . GLY A 1 34  ? 105.736 158.636 117.599 1.00 33.62  ?  34  GLY B CA    1 
ATOM 261  C C     . GLY A 1 34  ? 106.727 158.325 118.701 1.00 33.62  ?  34  GLY B C     1 
ATOM 262  O O     . GLY A 1 34  ? 106.842 159.044 119.689 1.00 33.62  ?  34  GLY B O     1 
ATOM 263  N N     . VAL A 1 35  ? 107.447 157.221 118.502 1.00 28.65  ?  35  VAL B N     1 
ATOM 264  C CA    . VAL A 1 35  ? 108.445 156.790 119.471 1.00 28.65  ?  35  VAL B CA    1 
ATOM 265  C C     . VAL A 1 35  ? 109.551 157.829 119.565 1.00 28.65  ?  35  VAL B C     1 
ATOM 266  O O     . VAL A 1 35  ? 110.032 158.348 118.550 1.00 28.65  ?  35  VAL B O     1 
ATOM 267  C CB    . VAL A 1 35  ? 109.008 155.412 119.084 1.00 28.65  ?  35  VAL B CB    1 
ATOM 268  C CG1   . VAL A 1 35  ? 110.160 155.032 119.996 1.00 28.65  ?  35  VAL B CG1   1 
ATOM 269  C CG2   . VAL A 1 35  ? 107.915 154.364 119.138 1.00 28.65  ?  35  VAL B CG2   1 
ATOM 270  N N     . ASN A 1 36  ? 109.958 158.143 120.791 1.00 35.85  ?  36  ASN B N     1 
ATOM 271  C CA    . ASN A 1 36  ? 111.007 159.118 121.033 1.00 35.85  ?  36  ASN B CA    1 
ATOM 272  C C     . ASN A 1 36  ? 111.954 158.573 122.090 1.00 35.85  ?  36  ASN B C     1 
ATOM 273  O O     . ASN A 1 36  ? 111.571 157.746 122.920 1.00 35.85  ?  36  ASN B O     1 
ATOM 274  C CB    . ASN A 1 36  ? 110.423 160.466 121.476 1.00 35.85  ?  36  ASN B CB    1 
ATOM 275  C CG    . ASN A 1 36  ? 111.452 161.580 121.481 1.00 35.85  ?  36  ASN B CG    1 
ATOM 276  O OD1   . ASN A 1 36  ? 112.654 161.337 121.587 1.00 35.85  ?  36  ASN B OD1   1 
ATOM 277  N ND2   . ASN A 1 36  ? 110.981 162.815 121.362 1.00 35.85  ?  36  ASN B ND2   1 
ATOM 278  N N     . LEU A 1 37  ? 113.197 159.042 122.046 1.00 27.68  ?  37  LEU B N     1 
ATOM 279  C CA    . LEU A 1 37  ? 114.207 158.634 123.009 1.00 27.68  ?  37  LEU B CA    1 
ATOM 280  C C     . LEU A 1 37  ? 115.151 159.799 123.245 1.00 27.68  ?  37  LEU B C     1 
ATOM 281  O O     . LEU A 1 37  ? 115.437 160.569 122.325 1.00 27.68  ?  37  LEU B O     1 
ATOM 282  C CB    . LEU A 1 37  ? 114.988 157.411 122.519 1.00 27.68  ?  37  LEU B CB    1 
ATOM 283  C CG    . LEU A 1 37  ? 115.738 156.586 123.566 1.00 27.68  ?  37  LEU B CG    1 
ATOM 284  C CD1   . LEU A 1 37  ? 115.782 155.130 123.146 1.00 27.68  ?  37  LEU B CD1   1 
ATOM 285  C CD2   . LEU A 1 37  ? 117.144 157.112 123.787 1.00 27.68  ?  37  LEU B CD2   1 
ATOM 286  N N     . GLN A 1 38  ? 115.624 159.927 124.482 1.00 47.56  ?  38  GLN B N     1 
ATOM 287  C CA    . GLN A 1 38  ? 116.641 160.923 124.811 1.00 47.56  ?  38  GLN B CA    1 
ATOM 288  C C     . GLN A 1 38  ? 117.300 160.482 126.109 1.00 47.56  ?  38  GLN B C     1 
ATOM 289  O O     . GLN A 1 38  ? 116.664 160.521 127.166 1.00 47.56  ?  38  GLN B O     1 
ATOM 290  C CB    . GLN A 1 38  ? 116.025 162.309 124.946 1.00 47.56  ?  38  GLN B CB    1 
ATOM 291  C CG    . GLN A 1 38  ? 116.904 163.310 125.668 1.00 47.56  ?  38  GLN B CG    1 
ATOM 292  C CD    . GLN A 1 38  ? 116.609 164.736 125.259 1.00 47.56  ?  38  GLN B CD    1 
ATOM 293  O OE1   . GLN A 1 38  ? 115.629 165.003 124.566 1.00 47.56  ?  38  GLN B OE1   1 
ATOM 294  N NE2   . GLN A 1 38  ? 117.457 165.662 125.687 1.00 47.56  ?  38  GLN B NE2   1 
ATOM 295  N N     . SER A 1 39  ? 118.560 160.063 126.032 1.00 44.95  ?  39  SER B N     1 
ATOM 296  C CA    . SER A 1 39  ? 119.245 159.556 127.218 1.00 44.95  ?  39  SER B CA    1 
ATOM 297  C C     . SER A 1 39  ? 120.741 159.754 127.035 1.00 44.95  ?  39  SER B C     1 
ATOM 298  O O     . SER A 1 39  ? 121.370 159.028 126.260 1.00 44.95  ?  39  SER B O     1 
ATOM 299  C CB    . SER A 1 39  ? 118.908 158.091 127.450 1.00 44.95  ?  39  SER B CB    1 
ATOM 300  O OG    . SER A 1 39  ? 119.561 157.268 126.502 1.00 44.95  ?  39  SER B OG    1 
ATOM 301  N N     . MET A 1 40  ? 121.301 160.720 127.752 1.00 57.12  ?  40  MET B N     1 
ATOM 302  C CA    . MET A 1 40  ? 122.732 160.961 127.713 1.00 57.12  ?  40  MET B CA    1 
ATOM 303  C C     . MET A 1 40  ? 123.482 159.762 128.293 1.00 57.12  ?  40  MET B C     1 
ATOM 304  O O     . MET A 1 40  ? 122.989 159.052 129.173 1.00 57.12  ?  40  MET B O     1 
ATOM 305  C CB    . MET A 1 40  ? 123.051 162.263 128.450 1.00 57.12  ?  40  MET B CB    1 
ATOM 306  C CG    . MET A 1 40  ? 122.898 162.212 129.956 1.00 57.12  ?  40  MET B CG    1 
ATOM 307  S SD    . MET A 1 40  ? 124.449 161.884 130.796 1.00 57.12  ?  40  MET B SD    1 
ATOM 308  C CE    . MET A 1 40  ? 125.189 163.514 130.690 1.00 57.12  ?  40  MET B CE    1 
ATOM 309  N N     . ASP A 1 41  ? 124.685 159.532 127.770 1.00 66.55  ?  41  ASP B N     1 
ATOM 310  C CA    . ASP A 1 41  ? 125.368 158.259 127.949 1.00 66.55  ?  41  ASP B CA    1 
ATOM 311  C C     . ASP A 1 41  ? 125.727 158.017 129.416 1.00 66.55  ?  41  ASP B C     1 
ATOM 312  O O     . ASP A 1 41  ? 125.674 158.914 130.262 1.00 66.55  ?  41  ASP B O     1 
ATOM 313  C CB    . ASP A 1 41  ? 126.628 158.200 127.087 1.00 66.55  ?  41  ASP B CB    1 
ATOM 314  C CG    . ASP A 1 41  ? 127.695 159.170 127.547 1.00 66.55  ?  41  ASP B CG    1 
ATOM 315  O OD1   . ASP A 1 41  ? 127.342 160.215 128.130 1.00 66.55  ?  41  ASP B OD1   1 
ATOM 316  O OD2   . ASP A 1 41  ? 128.890 158.887 127.324 1.00 66.55  -1 41  ASP B OD2   1 
ATOM 317  N N     . SER A 1 42  ? 126.103 156.768 129.704 1.00 74.92  ?  42  SER B N     1 
ATOM 318  C CA    . SER A 1 42  ? 126.439 156.379 131.070 1.00 74.92  ?  42  SER B CA    1 
ATOM 319  C C     . SER A 1 42  ? 127.700 157.081 131.557 1.00 74.92  ?  42  SER B C     1 
ATOM 320  O O     . SER A 1 42  ? 127.808 157.425 132.739 1.00 74.92  ?  42  SER B O     1 
ATOM 321  C CB    . SER A 1 42  ? 126.600 154.862 131.157 1.00 74.92  ?  42  SER B CB    1 
ATOM 322  O OG    . SER A 1 42  ? 125.451 154.199 130.660 1.00 74.92  ?  42  SER B OG    1 
ATOM 323  N N     . SER A 1 43  ? 128.667 157.298 130.664 1.00 71.26  ?  43  SER B N     1 
ATOM 324  C CA    . SER A 1 43  ? 129.864 158.045 131.029 1.00 71.26  ?  43  SER B CA    1 
ATOM 325  C C     . SER A 1 43  ? 129.583 159.525 131.242 1.00 71.26  ?  43  SER B C     1 
ATOM 326  O O     . SER A 1 43  ? 130.473 160.246 131.706 1.00 71.26  ?  43  SER B O     1 
ATOM 327  C CB    . SER A 1 43  ? 130.941 157.872 129.957 1.00 71.26  ?  43  SER B CB    1 
ATOM 328  O OG    . SER A 1 43  ? 131.809 158.991 129.925 1.00 71.26  ?  43  SER B OG    1 
ATOM 329  N N     . HIS A 1 44  ? 128.377 159.986 130.905 1.00 70.87  ?  44  HIS B N     1 
ATOM 330  C CA    . HIS A 1 44  ? 127.960 161.372 131.110 1.00 70.87  ?  44  HIS B CA    1 
ATOM 331  C C     . HIS A 1 44  ? 128.850 162.345 130.340 1.00 70.87  ?  44  HIS B C     1 
ATOM 332  O O     . HIS A 1 44  ? 129.281 163.373 130.865 1.00 70.87  ?  44  HIS B O     1 
ATOM 333  C CB    . HIS A 1 44  ? 127.913 161.722 132.599 1.00 70.87  ?  44  HIS B CB    1 
ATOM 334  C CG    . HIS A 1 44  ? 126.709 161.178 133.304 1.00 70.87  ?  44  HIS B CG    1 
ATOM 335  N ND1   . HIS A 1 44  ? 125.564 161.919 133.504 1.00 70.87  ?  44  HIS B ND1   1 
ATOM 336  C CD2   . HIS A 1 44  ? 126.466 159.959 133.841 1.00 70.87  ?  44  HIS B CD2   1 
ATOM 337  C CE1   . HIS A 1 44  ? 124.671 161.183 134.142 1.00 70.87  ?  44  HIS B CE1   1 
ATOM 338  N NE2   . HIS A 1 44  ? 125.193 159.989 134.357 1.00 70.87  ?  44  HIS B NE2   1 
ATOM 339  N N     . VAL A 1 45  ? 129.126 162.011 129.079 1.00 63.24  ?  45  VAL B N     1 
ATOM 340  C CA    . VAL A 1 45  ? 129.867 162.872 128.167 1.00 63.24  ?  45  VAL B CA    1 
ATOM 341  C C     . VAL A 1 45  ? 129.074 163.148 126.894 1.00 63.24  ?  45  VAL B C     1 
ATOM 342  O O     . VAL A 1 45  ? 128.985 164.293 126.439 1.00 63.24  ?  45  VAL B O     1 
ATOM 343  C CB    . VAL A 1 45  ? 131.250 162.274 127.827 1.00 63.24  ?  45  VAL B CB    1 
ATOM 344  C CG1   . VAL A 1 45  ? 131.957 163.129 126.788 1.00 63.24  ?  45  VAL B CG1   1 
ATOM 345  C CG2   . VAL A 1 45  ? 132.095 162.148 129.082 1.00 63.24  ?  45  VAL B CG2   1 
ATOM 346  N N     . SER A 1 46  ? 128.481 162.110 126.311 1.00 53.75  ?  46  SER B N     1 
ATOM 347  C CA    . SER A 1 46  ? 127.794 162.205 125.032 1.00 53.75  ?  46  SER B CA    1 
ATOM 348  C C     . SER A 1 46  ? 126.289 162.072 125.220 1.00 53.75  ?  46  SER B C     1 
ATOM 349  O O     . SER A 1 46  ? 125.824 161.312 126.074 1.00 53.75  ?  46  SER B O     1 
ATOM 350  C CB    . SER A 1 46  ? 128.288 161.126 124.068 1.00 53.75  ?  46  SER B CB    1 
ATOM 351  O OG    . SER A 1 46  ? 127.868 159.842 124.492 1.00 53.75  ?  46  SER B OG    1 
ATOM 352  N N     . LEU A 1 47  ? 125.535 162.806 124.408 1.00 42.12  ?  47  LEU B N     1 
ATOM 353  C CA    . LEU A 1 47  ? 124.081 162.790 124.437 1.00 42.12  ?  47  LEU B CA    1 
ATOM 354  C C     . LEU A 1 47  ? 123.551 162.149 123.161 1.00 42.12  ?  47  LEU B C     1 
ATOM 355  O O     . LEU A 1 47  ? 124.097 162.366 122.076 1.00 42.12  ?  47  LEU B O     1 
ATOM 356  C CB    . LEU A 1 47  ? 123.522 164.206 124.582 1.00 42.12  ?  47  LEU B CB    1 
ATOM 357  C CG    . LEU A 1 47  ? 122.004 164.364 124.528 1.00 42.12  ?  47  LEU B CG    1 
ATOM 358  C CD1   . LEU A 1 47  ? 121.425 164.415 125.928 1.00 42.12  ?  47  LEU B CD1   1 
ATOM 359  C CD2   . LEU A 1 47  ? 121.627 165.605 123.743 1.00 42.12  ?  47  LEU B CD2   1 
ATOM 360  N N     . VAL A 1 48  ? 122.488 161.359 123.297 1.00 31.96  ?  48  VAL B N     1 
ATOM 361  C CA    . VAL A 1 48  ? 121.896 160.628 122.183 1.00 31.96  ?  48  VAL B CA    1 
ATOM 362  C C     . VAL A 1 48  ? 120.412 160.957 122.119 1.00 31.96  ?  48  VAL B C     1 
ATOM 363  O O     . VAL A 1 48  ? 119.730 160.970 123.148 1.00 31.96  ?  48  VAL B O     1 
ATOM 364  C CB    . VAL A 1 48  ? 122.102 159.109 122.325 1.00 31.96  ?  48  VAL B CB    1 
ATOM 365  C CG1   . VAL A 1 48  ? 121.352 158.365 121.238 1.00 31.96  ?  48  VAL B CG1   1 
ATOM 366  C CG2   . VAL A 1 48  ? 123.577 158.769 122.285 1.00 31.96  ?  48  VAL B CG2   1 
ATOM 367  N N     . GLN A 1 49  ? 119.916 161.225 120.915 1.00 32.22  ?  49  GLN B N     1 
ATOM 368  C CA    . GLN A 1 49  ? 118.502 161.470 120.689 1.00 32.22  ?  49  GLN B CA    1 
ATOM 369  C C     . GLN A 1 49  ? 118.021 160.575 119.557 1.00 32.22  ?  49  GLN B C     1 
ATOM 370  O O     . GLN A 1 49  ? 118.805 160.152 118.706 1.00 32.22  ?  49  GLN B O     1 
ATOM 371  C CB    . GLN A 1 49  ? 118.231 162.940 120.354 1.00 32.22  ?  49  GLN B CB    1 
ATOM 372  C CG    . GLN A 1 49  ? 116.765 163.325 120.399 1.00 32.22  ?  49  GLN B CG    1 
ATOM 373  C CD    . GLN A 1 49  ? 116.471 164.587 119.622 1.00 32.22  ?  49  GLN B CD    1 
ATOM 374  O OE1   . GLN A 1 49  ? 117.379 165.241 119.112 1.00 32.22  ?  49  GLN B OE1   1 
ATOM 375  N NE2   . GLN A 1 49  ? 115.195 164.936 119.523 1.00 32.22  ?  49  GLN B NE2   1 
ATOM 376  N N     . LEU A 1 50  ? 116.723 160.282 119.560 1.00 32.02  ?  50  LEU B N     1 
ATOM 377  C CA    . LEU A 1 50  ? 116.133 159.409 118.557 1.00 32.02  ?  50  LEU B CA    1 
ATOM 378  C C     . LEU A 1 50  ? 114.685 159.820 118.345 1.00 32.02  ?  50  LEU B C     1 
ATOM 379  O O     . LEU A 1 50  ? 113.998 160.201 119.294 1.00 32.02  ?  50  LEU B O     1 
ATOM 380  C CB    . LEU A 1 50  ? 116.215 157.942 118.988 1.00 32.02  ?  50  LEU B CB    1 
ATOM 381  C CG    . LEU A 1 50  ? 116.401 156.868 117.917 1.00 32.02  ?  50  LEU B CG    1 
ATOM 382  C CD1   . LEU A 1 50  ? 116.759 155.555 118.576 1.00 32.02  ?  50  LEU B CD1   1 
ATOM 383  C CD2   . LEU A 1 50  ? 115.159 156.701 117.066 1.00 32.02  ?  50  LEU B CD2   1 
ATOM 384  N N     . THR A 1 51  ? 114.230 159.743 117.098 1.00 27.87  ?  51  THR B N     1 
ATOM 385  C CA    . THR A 1 51  ? 112.850 160.058 116.766 1.00 27.87  ?  51  THR B CA    1 
ATOM 386  C C     . THR A 1 51  ? 112.350 159.077 115.718 1.00 27.87  ?  51  THR B C     1 
ATOM 387  O O     . THR A 1 51  ? 113.090 158.701 114.806 1.00 27.87  ?  51  THR B O     1 
ATOM 388  C CB    . THR A 1 51  ? 112.712 161.494 116.248 1.00 27.87  ?  51  THR B CB    1 
ATOM 389  O OG1   . THR A 1 51  ? 113.430 162.382 117.112 1.00 27.87  ?  51  THR B OG1   1 
ATOM 390  C CG2   . THR A 1 51  ? 111.252 161.910 116.213 1.00 27.87  ?  51  THR B CG2   1 
ATOM 391  N N     . LEU A 1 52  ? 111.093 158.663 115.858 1.00 35.36  ?  52  LEU B N     1 
ATOM 392  C CA    . LEU A 1 52  ? 110.443 157.774 114.895 1.00 35.36  ?  52  LEU B CA    1 
ATOM 393  C C     . LEU A 1 52  ? 109.008 158.262 114.729 1.00 35.36  ?  52  LEU B C     1 
ATOM 394  O O     . LEU A 1 52  ? 108.155 157.993 115.578 1.00 35.36  ?  52  LEU B O     1 
ATOM 395  C CB    . LEU A 1 52  ? 110.486 156.323 115.355 1.00 35.36  ?  52  LEU B CB    1 
ATOM 396  C CG    . LEU A 1 52  ? 111.810 155.580 115.183 1.00 35.36  ?  52  LEU B CG    1 
ATOM 397  C CD1   . LEU A 1 52  ? 112.138 154.784 116.431 1.00 35.36  ?  52  LEU B CD1   1 
ATOM 398  C CD2   . LEU A 1 52  ? 111.746 154.669 113.976 1.00 35.36  ?  52  LEU B CD2   1 
ATOM 399  N N     . ARG A 1 53  ? 108.749 158.979 113.640 1.00 42.84  ?  53  ARG B N     1 
ATOM 400  C CA    . ARG A 1 53  ? 107.427 159.539 113.413 1.00 42.84  ?  53  ARG B CA    1 
ATOM 401  C C     . ARG A 1 53  ? 106.398 158.434 113.207 1.00 42.84  ?  53  ARG B C     1 
ATOM 402  O O     . ARG A 1 53  ? 106.712 157.339 112.734 1.00 42.84  ?  53  ARG B O     1 
ATOM 403  C CB    . ARG A 1 53  ? 107.443 160.475 112.205 1.00 42.84  ?  53  ARG B CB    1 
ATOM 404  C CG    . ARG A 1 53  ? 108.027 161.845 112.497 1.00 42.84  ?  53  ARG B CG    1 
ATOM 405  C CD    . ARG A 1 53  ? 108.258 162.629 111.219 1.00 42.84  ?  53  ARG B CD    1 
ATOM 406  N NE    . ARG A 1 53  ? 109.228 161.975 110.351 1.00 42.84  ?  53  ARG B NE    1 
ATOM 407  C CZ    . ARG A 1 53  ? 110.513 162.295 110.290 1.00 42.84  ?  53  ARG B CZ    1 
ATOM 408  N NH1   . ARG A 1 53  ? 111.021 163.261 111.038 1.00 42.84  1  53  ARG B NH1   1 
ATOM 409  N NH2   . ARG A 1 53  ? 111.309 161.628 109.460 1.00 42.84  ?  53  ARG B NH2   1 
ATOM 410  N N     . SER A 1 54  ? 105.152 158.736 113.577 1.00 45.50  ?  54  SER B N     1 
ATOM 411  C CA    . SER A 1 54  ? 104.089 157.741 113.490 1.00 45.50  ?  54  SER B CA    1 
ATOM 412  C C     . SER A 1 54  ? 103.803 157.337 112.051 1.00 45.50  ?  54  SER B C     1 
ATOM 413  O O     . SER A 1 54  ? 103.331 156.223 111.803 1.00 45.50  ?  54  SER B O     1 
ATOM 414  C CB    . SER A 1 54  ? 102.818 158.274 114.147 1.00 45.50  ?  54  SER B CB    1 
ATOM 415  O OG    . SER A 1 54  ? 102.380 159.459 113.507 1.00 45.50  ?  54  SER B OG    1 
ATOM 416  N N     . GLU A 1 55  ? 104.074 158.224 111.091 1.00 53.26  ?  55  GLU B N     1 
ATOM 417  C CA    . GLU A 1 55  ? 103.790 157.903 109.696 1.00 53.26  ?  55  GLU B CA    1 
ATOM 418  C C     . GLU A 1 55  ? 104.658 156.758 109.192 1.00 53.26  ?  55  GLU B C     1 
ATOM 419  O O     . GLU A 1 55  ? 104.262 156.047 108.262 1.00 53.26  ?  55  GLU B O     1 
ATOM 420  C CB    . GLU A 1 55  ? 103.979 159.144 108.822 1.00 53.26  ?  55  GLU B CB    1 
ATOM 421  C CG    . GLU A 1 55  ? 105.426 159.460 108.479 1.00 53.26  ?  55  GLU B CG    1 
ATOM 422  C CD    . GLU A 1 55  ? 105.702 160.949 108.425 1.00 53.26  ?  55  GLU B CD    1 
ATOM 423  O OE1   . GLU A 1 55  ? 104.748 161.725 108.211 1.00 53.26  ?  55  GLU B OE1   1 
ATOM 424  O OE2   . GLU A 1 55  ? 106.875 161.343 108.595 1.00 53.26  -1 55  GLU B OE2   1 
ATOM 425  N N     . GLY A 1 56  ? 105.839 156.567 109.782 1.00 50.83  ?  56  GLY B N     1 
ATOM 426  C CA    . GLY A 1 56  ? 106.711 155.494 109.336 1.00 50.83  ?  56  GLY B CA    1 
ATOM 427  C C     . GLY A 1 56  ? 106.160 154.114 109.638 1.00 50.83  ?  56  GLY B C     1 
ATOM 428  O O     . GLY A 1 56  ? 106.239 153.209 108.803 1.00 50.83  ?  56  GLY B O     1 
ATOM 429  N N     . PHE A 1 57  ? 105.605 153.931 110.833 1.00 46.25  ?  57  PHE B N     1 
ATOM 430  C CA    . PHE A 1 57  ? 105.041 152.642 111.204 1.00 46.25  ?  57  PHE B CA    1 
ATOM 431  C C     . PHE A 1 57  ? 103.833 152.321 110.335 1.00 46.25  ?  57  PHE B C     1 
ATOM 432  O O     . PHE A 1 57  ? 102.994 153.185 110.065 1.00 46.25  ?  57  PHE B O     1 
ATOM 433  C CB    . PHE A 1 57  ? 104.637 152.643 112.676 1.00 46.25  ?  57  PHE B CB    1 
ATOM 434  C CG    . PHE A 1 57  ? 105.798 152.693 113.621 1.00 46.25  ?  57  PHE B CG    1 
ATOM 435  C CD1   . PHE A 1 57  ? 106.332 153.903 114.014 1.00 46.25  ?  57  PHE B CD1   1 
ATOM 436  C CD2   . PHE A 1 57  ? 106.352 151.529 114.118 1.00 46.25  ?  57  PHE B CD2   1 
ATOM 437  C CE1   . PHE A 1 57  ? 107.400 153.951 114.885 1.00 46.25  ?  57  PHE B CE1   1 
ATOM 438  C CE2   . PHE A 1 57  ? 107.419 151.572 114.989 1.00 46.25  ?  57  PHE B CE2   1 
ATOM 439  C CZ    . PHE A 1 57  ? 107.943 152.784 115.373 1.00 46.25  ?  57  PHE B CZ    1 
ATOM 440  N N     . ASP A 1 58  ? 103.751 151.067 109.888 1.00 41.96  ?  58  ASP B N     1 
ATOM 441  C CA    . ASP A 1 58  ? 102.619 150.658 109.064 1.00 41.96  ?  58  ASP B CA    1 
ATOM 442  C C     . ASP A 1 58  ? 101.312 150.746 109.839 1.00 41.96  ?  58  ASP B C     1 
ATOM 443  O O     . ASP A 1 58  ? 100.292 151.195 109.302 1.00 41.96  ?  58  ASP B O     1 
ATOM 444  C CB    . ASP A 1 58  ? 102.839 149.242 108.535 1.00 41.96  ?  58  ASP B CB    1 
ATOM 445  C CG    . ASP A 1 58  ? 102.208 149.027 107.176 1.00 41.96  ?  58  ASP B CG    1 
ATOM 446  O OD1   . ASP A 1 58  ? 101.025 149.388 107.007 1.00 41.96  ?  58  ASP B OD1   1 
ATOM 447  O OD2   . ASP A 1 58  ? 102.893 148.503 106.275 1.00 41.96  -1 58  ASP B OD2   1 
ATOM 448  N N     . THR A 1 59  ? 101.320 150.327 111.102 1.00 39.37  ?  59  THR B N     1 
ATOM 449  C CA    . THR A 1 59  ? 100.145 150.395 111.962 1.00 39.37  ?  59  THR B CA    1 
ATOM 450  C C     . THR A 1 59  ? 100.567 150.952 113.311 1.00 39.37  ?  59  THR B C     1 
ATOM 451  O O     . THR A 1 59  ? 101.464 150.402 113.958 1.00 39.37  ?  59  THR B O     1 
ATOM 452  C CB    . THR A 1 59  ? 99.496  149.019 112.127 1.00 39.37  ?  59  THR B CB    1 
ATOM 453  O OG1   . THR A 1 59  ? 98.970  148.584 110.868 1.00 39.37  ?  59  THR B OG1   1 
ATOM 454  C CG2   . THR A 1 59  ? 98.370  149.083 113.144 1.00 39.37  ?  59  THR B CG2   1 
ATOM 455  N N     . TYR A 1 60  ? 99.922  152.034 113.734 1.00 38.54  ?  60  TYR B N     1 
ATOM 456  C CA    . TYR A 1 60  ? 100.266 152.719 114.969 1.00 38.54  ?  60  TYR B CA    1 
ATOM 457  C C     . TYR A 1 60  ? 99.001  153.062 115.738 1.00 38.54  ?  60  TYR B C     1 
ATOM 458  O O     . TYR A 1 60  ? 97.991  153.452 115.144 1.00 38.54  ?  60  TYR B O     1 
ATOM 459  C CB    . TYR A 1 60  ? 101.062 153.996 114.683 1.00 38.54  ?  60  TYR B CB    1 
ATOM 460  C CG    . TYR A 1 60  ? 101.941 154.452 115.823 1.00 38.54  ?  60  TYR B CG    1 
ATOM 461  C CD1   . TYR A 1 60  ? 101.413 155.158 116.892 1.00 38.54  ?  60  TYR B CD1   1 
ATOM 462  C CD2   . TYR A 1 60  ? 103.301 154.186 115.823 1.00 38.54  ?  60  TYR B CD2   1 
ATOM 463  C CE1   . TYR A 1 60  ? 102.212 155.579 117.931 1.00 38.54  ?  60  TYR B CE1   1 
ATOM 464  C CE2   . TYR A 1 60  ? 104.108 154.604 116.858 1.00 38.54  ?  60  TYR B CE2   1 
ATOM 465  C CZ    . TYR A 1 60  ? 103.558 155.299 117.909 1.00 38.54  ?  60  TYR B CZ    1 
ATOM 466  O OH    . TYR A 1 60  ? 104.360 155.718 118.944 1.00 38.54  ?  60  TYR B OH    1 
ATOM 467  N N     . ARG A 1 61  ? 99.061  152.916 117.060 1.00 46.17  ?  61  ARG B N     1 
ATOM 468  C CA    . ARG A 1 61  ? 97.960  153.326 117.918 1.00 46.17  ?  61  ARG B CA    1 
ATOM 469  C C     . ARG A 1 61  ? 98.483  153.494 119.337 1.00 46.17  ?  61  ARG B C     1 
ATOM 470  O O     . ARG A 1 61  ? 99.270  152.675 119.816 1.00 46.17  ?  61  ARG B O     1 
ATOM 471  C CB    . ARG A 1 61  ? 96.806  152.316 117.877 1.00 46.17  ?  61  ARG B CB    1 
ATOM 472  C CG    . ARG A 1 61  ? 97.134  150.945 118.434 1.00 46.17  ?  61  ARG B CG    1 
ATOM 473  C CD    . ARG A 1 61  ? 95.936  150.376 119.173 1.00 46.17  ?  61  ARG B CD    1 
ATOM 474  N NE    . ARG A 1 61  ? 95.793  150.958 120.502 1.00 46.17  ?  61  ARG B NE    1 
ATOM 475  C CZ    . ARG A 1 61  ? 94.833  150.642 121.359 1.00 46.17  ?  61  ARG B CZ    1 
ATOM 476  N NH1   . ARG A 1 61  ? 93.919  149.731 121.068 1.00 46.17  1  61  ARG B NH1   1 
ATOM 477  N NH2   . ARG A 1 61  ? 94.799  151.241 122.546 1.00 46.17  ?  61  ARG B NH2   1 
ATOM 478  N N     . CYS A 1 62  ? 98.053  154.570 119.992 1.00 47.62  ?  62  CYS B N     1 
ATOM 479  C CA    . CYS A 1 62  ? 98.463  154.853 121.362 1.00 47.62  ?  62  CYS B CA    1 
ATOM 480  C C     . CYS A 1 62  ? 97.473  155.833 121.969 1.00 47.62  ?  62  CYS B C     1 
ATOM 481  O O     . CYS A 1 62  ? 97.164  156.860 121.358 1.00 47.62  ?  62  CYS B O     1 
ATOM 482  C CB    . CYS A 1 62  ? 99.881  155.427 121.414 1.00 47.62  ?  62  CYS B CB    1 
ATOM 483  S SG    . CYS A 1 62  ? 100.322 156.135 123.014 1.00 47.62  ?  62  CYS B SG    1 
ATOM 484  N N     . ASP A 1 63  ? 96.985  155.516 123.166 1.00 52.28  ?  63  ASP B N     1 
ATOM 485  C CA    . ASP A 1 63  ? 95.976  156.324 123.839 1.00 52.28  ?  63  ASP B CA    1 
ATOM 486  C C     . ASP A 1 63  ? 96.581  157.327 124.813 1.00 52.28  ?  63  ASP B C     1 
ATOM 487  O O     . ASP A 1 63  ? 96.225  158.509 124.788 1.00 52.28  ?  63  ASP B O     1 
ATOM 488  C CB    . ASP A 1 63  ? 94.989  155.413 124.577 1.00 52.28  ?  63  ASP B CB    1 
ATOM 489  C CG    . ASP A 1 63  ? 94.531  154.247 123.727 1.00 52.28  ?  63  ASP B CG    1 
ATOM 490  O OD1   . ASP A 1 63  ? 94.526  154.382 122.486 1.00 52.28  ?  63  ASP B OD1   1 
ATOM 491  O OD2   . ASP A 1 63  ? 94.180  153.194 124.299 1.00 52.28  -1 63  ASP B OD2   1 
ATOM 492  N N     . ARG A 1 64  ? 97.492  156.879 125.671 1.00 49.59  ?  64  ARG B N     1 
ATOM 493  C CA    . ARG A 1 64  ? 98.095  157.723 126.690 1.00 49.59  ?  64  ARG B CA    1 
ATOM 494  C C     . ARG A 1 64  ? 99.609  157.649 126.574 1.00 49.59  ?  64  ARG B C     1 
ATOM 495  O O     . ARG A 1 64  ? 100.163 156.588 126.274 1.00 49.59  ?  64  ARG B O     1 
ATOM 496  C CB    . ARG A 1 64  ? 97.639  157.295 128.093 1.00 49.59  ?  64  ARG B CB    1 
ATOM 497  C CG    . ARG A 1 64  ? 98.481  157.841 129.235 1.00 49.59  ?  64  ARG B CG    1 
ATOM 498  C CD    . ARG A 1 64  ? 98.355  157.036 130.536 1.00 49.59  ?  64  ARG B CD    1 
ATOM 499  N NE    . ARG A 1 64  ? 98.549  155.598 130.374 1.00 49.59  ?  64  ARG B NE    1 
ATOM 500  C CZ    . ARG A 1 64  ? 97.585  154.726 130.105 1.00 49.59  ?  64  ARG B CZ    1 
ATOM 501  N NH1   . ARG A 1 64  ? 96.322  155.103 129.995 1.00 49.59  1  64  ARG B NH1   1 
ATOM 502  N NH2   . ARG A 1 64  ? 97.896  153.442 129.955 1.00 49.59  ?  64  ARG B NH2   1 
ATOM 503  N N     . ASN A 1 65  ? 100.270 158.782 126.797 1.00 44.92  ?  65  ASN B N     1 
ATOM 504  C CA    . ASN A 1 65  ? 101.725 158.812 126.764 1.00 44.92  ?  65  ASN B CA    1 
ATOM 505  C C     . ASN A 1 65  ? 102.296 157.917 127.855 1.00 44.92  ?  65  ASN B C     1 
ATOM 506  O O     . ASN A 1 65  ? 101.793 157.882 128.981 1.00 44.92  ?  65  ASN B O     1 
ATOM 507  C CB    . ASN A 1 65  ? 102.227 160.244 126.937 1.00 44.92  ?  65  ASN B CB    1 
ATOM 508  C CG    . ASN A 1 65  ? 101.465 161.233 126.082 1.00 44.92  ?  65  ASN B CG    1 
ATOM 509  O OD1   . ASN A 1 65  ? 100.868 160.864 125.072 1.00 44.92  ?  65  ASN B OD1   1 
ATOM 510  N ND2   . ASN A 1 65  ? 101.478 162.497 126.485 1.00 44.92  ?  65  ASN B ND2   1 
ATOM 511  N N     . LEU A 1 66  ? 103.351 157.188 127.516 1.00 41.03  ?  66  LEU B N     1 
ATOM 512  C CA    . LEU A 1 66  ? 103.971 156.225 128.413 1.00 41.03  ?  66  LEU B CA    1 
ATOM 513  C C     . LEU A 1 66  ? 105.416 156.625 128.690 1.00 41.03  ?  66  LEU B C     1 
ATOM 514  O O     . LEU A 1 66  ? 105.902 157.660 128.230 1.00 41.03  ?  66  LEU B O     1 
ATOM 515  C CB    . LEU A 1 66  ? 103.909 154.814 127.824 1.00 41.03  ?  66  LEU B CB    1 
ATOM 516  C CG    . LEU A 1 66  ? 102.571 154.367 127.238 1.00 41.03  ?  66  LEU B CG    1 
ATOM 517  C CD1   . LEU A 1 66  ? 102.682 152.957 126.691 1.00 41.03  ?  66  LEU B CD1   1 
ATOM 518  C CD2   . LEU A 1 66  ? 101.482 154.447 128.290 1.00 41.03  ?  66  LEU B CD2   1 
ATOM 519  N N     . ALA A 1 67  ? 106.097 155.781 129.461 1.00 41.50  ?  67  ALA B N     1 
ATOM 520  C CA    . ALA A 1 67  ? 107.520 155.961 129.734 1.00 41.50  ?  67  ALA B CA    1 
ATOM 521  C C     . ALA A 1 67  ? 108.066 154.609 130.168 1.00 41.50  ?  67  ALA B C     1 
ATOM 522  O O     . ALA A 1 67  ? 107.725 154.128 131.253 1.00 41.50  ?  67  ALA B O     1 
ATOM 523  C CB    . ALA A 1 67  ? 107.745 157.021 130.803 1.00 41.50  ?  67  ALA B CB    1 
ATOM 524  N N     . MET A 1 68  ? 108.901 154.005 129.332 1.00 48.01  ?  68  MET B N     1 
ATOM 525  C CA    . MET A 1 68  ? 109.411 152.662 129.569 1.00 48.01  ?  68  MET B CA    1 
ATOM 526  C C     . MET A 1 68  ? 110.908 152.711 129.831 1.00 48.01  ?  68  MET B C     1 
ATOM 527  O O     . MET A 1 68  ? 111.668 153.250 129.021 1.00 48.01  ?  68  MET B O     1 
ATOM 528  C CB    . MET A 1 68  ? 109.119 151.751 128.376 1.00 48.01  ?  68  MET B CB    1 
ATOM 529  C CG    . MET A 1 68  ? 107.710 151.197 128.354 1.00 48.01  ?  68  MET B CG    1 
ATOM 530  S SD    . MET A 1 68  ? 106.522 152.351 127.651 1.00 48.01  ?  68  MET B SD    1 
ATOM 531  C CE    . MET A 1 68  ? 106.304 151.644 126.022 1.00 48.01  ?  68  MET B CE    1 
ATOM 532  N N     . GLY A 1 69  ? 111.324 152.148 130.960 1.00 65.77  ?  69  GLY B N     1 
ATOM 533  C CA    . GLY A 1 69  ? 112.732 151.943 131.222 1.00 65.77  ?  69  GLY B CA    1 
ATOM 534  C C     . GLY A 1 69  ? 113.139 150.540 130.831 1.00 65.77  ?  69  GLY B C     1 
ATOM 535  O O     . GLY A 1 69  ? 112.809 149.576 131.527 1.00 65.77  ?  69  GLY B O     1 
ATOM 536  N N     . VAL A 1 70  ? 113.844 150.406 129.712 1.00 58.39  ?  70  VAL B N     1 
ATOM 537  C CA    . VAL A 1 70  ? 114.172 149.110 129.134 1.00 58.39  ?  70  VAL B CA    1 
ATOM 538  C C     . VAL A 1 70  ? 115.683 148.947 129.127 1.00 58.39  ?  70  VAL B C     1 
ATOM 539  O O     . VAL A 1 70  ? 116.408 149.866 128.733 1.00 58.39  ?  70  VAL B O     1 
ATOM 540  C CB    . VAL A 1 70  ? 113.606 148.969 127.710 1.00 58.39  ?  70  VAL B CB    1 
ATOM 541  C CG1   . VAL A 1 70  ? 113.773 147.545 127.218 1.00 58.39  ?  70  VAL B CG1   1 
ATOM 542  C CG2   . VAL A 1 70  ? 112.146 149.385 127.679 1.00 58.39  ?  70  VAL B CG2   1 
ATOM 543  N N     . ASN A 1 71  ? 116.154 147.785 129.570 1.00 57.90  ?  71  ASN B N     1 
ATOM 544  C CA    . ASN A 1 71  ? 117.574 147.472 129.491 1.00 57.90  ?  71  ASN B CA    1 
ATOM 545  C C     . ASN A 1 71  ? 117.971 147.306 128.029 1.00 57.90  ?  71  ASN B C     1 
ATOM 546  O O     . ASN A 1 71  ? 117.468 146.413 127.340 1.00 57.90  ?  71  ASN B O     1 
ATOM 547  C CB    . ASN A 1 71  ? 117.882 146.205 130.283 1.00 57.90  ?  71  ASN B CB    1 
ATOM 548  C CG    . ASN A 1 71  ? 119.363 146.036 130.564 1.00 57.90  ?  71  ASN B CG    1 
ATOM 549  O OD1   . ASN A 1 71  ? 120.208 146.356 129.728 1.00 57.90  ?  71  ASN B OD1   1 
ATOM 550  N ND2   . ASN A 1 71  ? 119.684 145.530 131.748 1.00 57.90  ?  71  ASN B ND2   1 
ATOM 551  N N     . LEU A 1 72  ? 118.874 148.167 127.556 1.00 51.63  ?  72  LEU B N     1 
ATOM 552  C CA    . LEU A 1 72  ? 119.218 148.168 126.138 1.00 51.63  ?  72  LEU B CA    1 
ATOM 553  C C     . LEU A 1 72  ? 120.016 146.930 125.752 1.00 51.63  ?  72  LEU B C     1 
ATOM 554  O O     . LEU A 1 72  ? 119.903 146.445 124.622 1.00 51.63  ?  72  LEU B O     1 
ATOM 555  C CB    . LEU A 1 72  ? 119.989 149.437 125.782 1.00 51.63  ?  72  LEU B CB    1 
ATOM 556  C CG    . LEU A 1 72  ? 119.175 150.630 125.276 1.00 51.63  ?  72  LEU B CG    1 
ATOM 557  C CD1   . LEU A 1 72  ? 118.792 150.425 123.825 1.00 51.63  ?  72  LEU B CD1   1 
ATOM 558  C CD2   . LEU A 1 72  ? 117.933 150.866 126.114 1.00 51.63  ?  72  LEU B CD2   1 
ATOM 559  N N     . THR A 1 73  ? 120.838 146.411 126.666 1.00 52.17  ?  73  THR B N     1 
ATOM 560  C CA    . THR A 1 73  ? 121.610 145.211 126.356 1.00 52.17  ?  73  THR B CA    1 
ATOM 561  C C     . THR A 1 73  ? 120.697 144.012 126.128 1.00 52.17  ?  73  THR B C     1 
ATOM 562  O O     . THR A 1 73  ? 120.884 143.246 125.173 1.00 52.17  ?  73  THR B O     1 
ATOM 563  C CB    . THR A 1 73  ? 122.604 144.922 127.479 1.00 52.17  ?  73  THR B CB    1 
ATOM 564  O OG1   . THR A 1 73  ? 123.183 146.151 127.932 1.00 52.17  ?  73  THR B OG1   1 
ATOM 565  C CG2   . THR A 1 73  ? 123.709 144.005 126.984 1.00 52.17  ?  73  THR B CG2   1 
ATOM 566  N N     . SER A 1 74  ? 119.695 143.839 126.992 1.00 51.57  ?  74  SER B N     1 
ATOM 567  C CA    . SER A 1 74  ? 118.753 142.739 126.821 1.00 51.57  ?  74  SER B CA    1 
ATOM 568  C C     . SER A 1 74  ? 117.950 142.897 125.538 1.00 51.57  ?  74  SER B C     1 
ATOM 569  O O     . SER A 1 74  ? 117.689 141.915 124.835 1.00 51.57  ?  74  SER B O     1 
ATOM 570  C CB    . SER A 1 74  ? 117.827 142.653 128.032 1.00 51.57  ?  74  SER B CB    1 
ATOM 571  O OG    . SER A 1 74  ? 118.565 142.703 129.239 1.00 51.57  ?  74  SER B OG    1 
ATOM 572  N N     . MET A 1 75  ? 117.543 144.127 125.218 1.00 48.43  ?  75  MET B N     1 
ATOM 573  C CA    . MET A 1 75  ? 116.802 144.356 123.983 1.00 48.43  ?  75  MET B CA    1 
ATOM 574  C C     . MET A 1 75  ? 117.659 144.057 122.763 1.00 48.43  ?  75  MET B C     1 
ATOM 575  O O     . MET A 1 75  ? 117.169 143.498 121.777 1.00 48.43  ?  75  MET B O     1 
ATOM 576  C CB    . MET A 1 75  ? 116.279 145.789 123.936 1.00 48.43  ?  75  MET B CB    1 
ATOM 577  C CG    . MET A 1 75  ? 114.913 145.916 123.290 1.00 48.43  ?  75  MET B CG    1 
ATOM 578  S SD    . MET A 1 75  ? 114.221 147.571 123.442 1.00 48.43  ?  75  MET B SD    1 
ATOM 579  C CE    . MET A 1 75  ? 112.801 147.441 122.361 1.00 48.43  ?  75  MET B CE    1 
ATOM 580  N N     . SER A 1 76  ? 118.940 144.428 122.806 1.00 46.86  ?  76  SER B N     1 
ATOM 581  C CA    . SER A 1 76  ? 119.838 144.099 121.706 1.00 46.86  ?  76  SER B CA    1 
ATOM 582  C C     . SER A 1 76  ? 119.993 142.593 121.557 1.00 46.86  ?  76  SER B C     1 
ATOM 583  O O     . SER A 1 76  ? 119.980 142.067 120.438 1.00 46.86  ?  76  SER B O     1 
ATOM 584  C CB    . SER A 1 76  ? 121.198 144.757 121.922 1.00 46.86  ?  76  SER B CB    1 
ATOM 585  O OG    . SER A 1 76  ? 122.193 144.121 121.142 1.00 46.86  ?  76  SER B OG    1 
ATOM 586  N N     . LYS A 1 77  ? 120.136 141.881 122.677 1.00 48.08  ?  77  LYS B N     1 
ATOM 587  C CA    . LYS A 1 77  ? 120.253 140.427 122.609 1.00 48.08  ?  77  LYS B CA    1 
ATOM 588  C C     . LYS A 1 77  ? 118.991 139.799 122.032 1.00 48.08  ?  77  LYS B C     1 
ATOM 589  O O     . LYS A 1 77  ? 119.066 138.856 121.236 1.00 48.08  ?  77  LYS B O     1 
ATOM 590  C CB    . LYS A 1 77  ? 120.554 139.853 123.991 1.00 48.08  ?  77  LYS B CB    1 
ATOM 591  C CG    . LYS A 1 77  ? 122.004 139.445 124.182 1.00 48.08  ?  77  LYS B CG    1 
ATOM 592  C CD    . LYS A 1 77  ? 122.220 138.770 125.526 1.00 48.08  ?  77  LYS B CD    1 
ATOM 593  C CE    . LYS A 1 77  ? 121.750 139.654 126.667 1.00 48.08  ?  77  LYS B CE    1 
ATOM 594  N NZ    . LYS A 1 77  ? 122.326 141.023 126.579 1.00 48.08  1  77  LYS B NZ    1 
ATOM 595  N N     . ILE A 1 78  ? 117.821 140.304 122.427 1.00 41.72  ?  78  ILE B N     1 
ATOM 596  C CA    . ILE A 1 78  ? 116.569 139.777 121.894 1.00 41.72  ?  78  ILE B CA    1 
ATOM 597  C C     . ILE A 1 78  ? 116.459 140.058 120.400 1.00 41.72  ?  78  ILE B C     1 
ATOM 598  O O     . ILE A 1 78  ? 116.094 139.175 119.614 1.00 41.72  ?  78  ILE B O     1 
ATOM 599  C CB    . ILE A 1 78  ? 115.374 140.356 122.673 1.00 41.72  ?  78  ILE B CB    1 
ATOM 600  C CG1   . ILE A 1 78  ? 115.084 139.505 123.907 1.00 41.72  ?  78  ILE B CG1   1 
ATOM 601  C CG2   . ILE A 1 78  ? 114.140 140.435 121.791 1.00 41.72  ?  78  ILE B CG2   1 
ATOM 602  C CD1   . ILE A 1 78  ? 113.885 139.970 124.698 1.00 41.72  ?  78  ILE B CD1   1 
ATOM 603  N N     . LEU A 1 79  ? 116.782 141.284 119.980 1.00 38.25  ?  79  LEU B N     1 
ATOM 604  C CA    . LEU A 1 79  ? 116.656 141.647 118.573 1.00 38.25  ?  79  LEU B CA    1 
ATOM 605  C C     . LEU A 1 79  ? 117.651 140.894 117.704 1.00 38.25  ?  79  LEU B C     1 
ATOM 606  O O     . LEU A 1 79  ? 117.376 140.647 116.525 1.00 38.25  ?  79  LEU B O     1 
ATOM 607  C CB    . LEU A 1 79  ? 116.840 143.152 118.398 1.00 38.25  ?  79  LEU B CB    1 
ATOM 608  C CG    . LEU A 1 79  ? 115.559 143.970 118.248 1.00 38.25  ?  79  LEU B CG    1 
ATOM 609  C CD1   . LEU A 1 79  ? 114.741 143.465 117.075 1.00 38.25  ?  79  LEU B CD1   1 
ATOM 610  C CD2   . LEU A 1 79  ? 114.749 143.927 119.524 1.00 38.25  ?  79  LEU B CD2   1 
ATOM 611  N N     . LYS A 1 80  ? 118.811 140.533 118.258 1.00 41.05  ?  80  LYS B N     1 
ATOM 612  C CA    . LYS A 1 80  ? 119.773 139.745 117.497 1.00 41.05  ?  80  LYS B CA    1 
ATOM 613  C C     . LYS A 1 80  ? 119.188 138.398 117.092 1.00 41.05  ?  80  LYS B C     1 
ATOM 614  O O     . LYS A 1 80  ? 119.535 137.861 116.034 1.00 41.05  ?  80  LYS B O     1 
ATOM 615  C CB    . LYS A 1 80  ? 121.053 139.566 118.315 1.00 41.05  ?  80  LYS B CB    1 
ATOM 616  C CG    . LYS A 1 80  ? 121.948 138.425 117.870 1.00 41.05  ?  80  LYS B CG    1 
ATOM 617  C CD    . LYS A 1 80  ? 122.528 137.690 119.065 1.00 41.05  ?  80  LYS B CD    1 
ATOM 618  C CE    . LYS A 1 80  ? 121.441 136.971 119.842 1.00 41.05  ?  80  LYS B CE    1 
ATOM 619  N NZ    . LYS A 1 80  ? 120.618 136.104 118.956 1.00 41.05  1  80  LYS B NZ    1 
ATOM 620  N N     . CYS A 1 81  ? 118.284 137.849 117.907 1.00 43.63  ?  81  CYS B N     1 
ATOM 621  C CA    . CYS A 1 81  ? 117.649 136.581 117.567 1.00 43.63  ?  81  CYS B CA    1 
ATOM 622  C C     . CYS A 1 81  ? 116.750 136.706 116.343 1.00 43.63  ?  81  CYS B C     1 
ATOM 623  O O     . CYS A 1 81  ? 116.598 135.739 115.588 1.00 43.63  ?  81  CYS B O     1 
ATOM 624  C CB    . CYS A 1 81  ? 116.850 136.058 118.760 1.00 43.63  ?  81  CYS B CB    1 
ATOM 625  S SG    . CYS A 1 81  ? 117.822 135.822 120.266 1.00 43.63  ?  81  CYS B SG    1 
ATOM 626  N N     . ALA A 1 82  ? 116.150 137.872 116.130 1.00 44.91  ?  82  ALA B N     1 
ATOM 627  C CA    . ALA A 1 82  ? 115.255 138.058 114.998 1.00 44.91  ?  82  ALA B CA    1 
ATOM 628  C C     . ALA A 1 82  ? 116.024 138.029 113.682 1.00 44.91  ?  82  ALA B C     1 
ATOM 629  O O     . ALA A 1 82  ? 117.213 138.353 113.621 1.00 44.91  ?  82  ALA B O     1 
ATOM 630  C CB    . ALA A 1 82  ? 114.498 139.379 115.126 1.00 44.91  ?  82  ALA B CB    1 
ATOM 631  N N     . GLY A 1 83  ? 115.328 137.636 112.620 1.00 49.81  ?  83  GLY B N     1 
ATOM 632  C CA    . GLY A 1 83  ? 115.910 137.582 111.298 1.00 49.81  ?  83  GLY B CA    1 
ATOM 633  C C     . GLY A 1 83  ? 115.970 138.952 110.648 1.00 49.81  ?  83  GLY B C     1 
ATOM 634  O O     . GLY A 1 83  ? 115.684 139.984 111.256 1.00 49.81  ?  83  GLY B O     1 
ATOM 635  N N     . ASN A 1 84  ? 116.353 138.949 109.373 1.00 52.57  ?  84  ASN B N     1 
ATOM 636  C CA    . ASN A 1 84  ? 116.583 140.180 108.629 1.00 52.57  ?  84  ASN B CA    1 
ATOM 637  C C     . ASN A 1 84  ? 115.366 140.656 107.846 1.00 52.57  ?  84  ASN B C     1 
ATOM 638  O O     . ASN A 1 84  ? 115.448 141.696 107.185 1.00 52.57  ?  84  ASN B O     1 
ATOM 639  C CB    . ASN A 1 84  ? 117.764 140.000 107.671 1.00 52.57  ?  84  ASN B CB    1 
ATOM 640  C CG    . ASN A 1 84  ? 119.076 140.453 108.275 1.00 52.57  ?  84  ASN B CG    1 
ATOM 641  O OD1   . ASN A 1 84  ? 119.106 141.338 109.129 1.00 52.57  ?  84  ASN B OD1   1 
ATOM 642  N ND2   . ASN A 1 84  ? 120.171 139.845 107.835 1.00 52.57  ?  84  ASN B ND2   1 
ATOM 643  N N     . GLU A 1 85  ? 114.246 139.930 107.893 1.00 56.24  ?  85  GLU B N     1 
ATOM 644  C CA    . GLU A 1 85  ? 113.078 140.338 107.121 1.00 56.24  ?  85  GLU B CA    1 
ATOM 645  C C     . GLU A 1 85  ? 111.769 140.144 107.881 1.00 56.24  ?  85  GLU B C     1 
ATOM 646  O O     . GLU A 1 85  ? 110.703 140.105 107.256 1.00 56.24  ?  85  GLU B O     1 
ATOM 647  C CB    . GLU A 1 85  ? 113.014 139.576 105.794 1.00 56.24  ?  85  GLU B CB    1 
ATOM 648  C CG    . GLU A 1 85  ? 112.972 138.065 105.946 1.00 56.24  ?  85  GLU B CG    1 
ATOM 649  C CD    . GLU A 1 85  ? 114.353 137.446 106.007 1.00 56.24  ?  85  GLU B CD    1 
ATOM 650  O OE1   . GLU A 1 85  ? 115.347 138.201 105.980 1.00 56.24  ?  85  GLU B OE1   1 
ATOM 651  O OE2   . GLU A 1 85  ? 114.445 136.203 106.084 1.00 56.24  -1 85  GLU B OE2   1 
ATOM 652  N N     . ASP A 1 86  ? 111.815 140.026 109.204 1.00 48.46  ?  86  ASP B N     1 
ATOM 653  C CA    . ASP A 1 86  ? 110.605 139.810 109.978 1.00 48.46  ?  86  ASP B CA    1 
ATOM 654  C C     . ASP A 1 86  ? 109.823 141.112 110.131 1.00 48.46  ?  86  ASP B C     1 
ATOM 655  O O     . ASP A 1 86  ? 110.257 142.186 109.709 1.00 48.46  ?  86  ASP B O     1 
ATOM 656  C CB    . ASP A 1 86  ? 110.947 139.225 111.344 1.00 48.46  ?  86  ASP B CB    1 
ATOM 657  C CG    . ASP A 1 86  ? 111.784 137.971 111.241 1.00 48.46  ?  86  ASP B CG    1 
ATOM 658  O OD1   . ASP A 1 86  ? 112.892 138.048 110.673 1.00 48.46  ?  86  ASP B OD1   1 
ATOM 659  O OD2   . ASP A 1 86  ? 111.336 136.909 111.724 1.00 48.46  -1 86  ASP B OD2   1 
ATOM 660  N N     . ILE A 1 87  ? 108.651 141.003 110.744 1.00 38.57  ?  87  ILE B N     1 
ATOM 661  C CA    . ILE A 1 87  ? 107.746 142.129 110.937 1.00 38.57  ?  87  ILE B CA    1 
ATOM 662  C C     . ILE A 1 87  ? 107.607 142.342 112.439 1.00 38.57  ?  87  ILE B C     1 
ATOM 663  O O     . ILE A 1 87  ? 106.774 141.705 113.093 1.00 38.57  ?  87  ILE B O     1 
ATOM 664  C CB    . ILE A 1 87  ? 106.386 141.887 110.277 1.00 38.57  ?  87  ILE B CB    1 
ATOM 665  C CG1   . ILE A 1 87  ? 106.569 141.209 108.920 1.00 38.57  ?  87  ILE B CG1   1 
ATOM 666  C CG2   . ILE A 1 87  ? 105.635 143.193 110.118 1.00 38.57  ?  87  ILE B CG2   1 
ATOM 667  C CD1   . ILE A 1 87  ? 105.273 140.764 108.285 1.00 38.57  ?  87  ILE B CD1   1 
ATOM 668  N N     . ILE A 1 88  ? 108.415 143.247 112.990 1.00 29.99  ?  88  ILE B N     1 
ATOM 669  C CA    . ILE A 1 88  ? 108.392 143.501 114.425 1.00 29.99  ?  88  ILE B CA    1 
ATOM 670  C C     . ILE A 1 88  ? 107.065 144.138 114.810 1.00 29.99  ?  88  ILE B C     1 
ATOM 671  O O     . ILE A 1 88  ? 106.545 145.012 114.104 1.00 29.99  ?  88  ILE B O     1 
ATOM 672  C CB    . ILE A 1 88  ? 109.573 144.395 114.829 1.00 29.99  ?  88  ILE B CB    1 
ATOM 673  C CG1   . ILE A 1 88  ? 110.830 144.001 114.057 1.00 29.99  ?  88  ILE B CG1   1 
ATOM 674  C CG2   . ILE A 1 88  ? 109.832 144.273 116.310 1.00 29.99  ?  88  ILE B CG2   1 
ATOM 675  C CD1   . ILE A 1 88  ? 111.366 142.642 114.405 1.00 29.99  ?  88  ILE B CD1   1 
ATOM 676  N N     . THR A 1 89  ? 106.505 143.699 115.933 1.00 34.20  ?  89  THR B N     1 
ATOM 677  C CA    . THR A 1 89  ? 105.169 144.100 116.365 1.00 34.20  ?  89  THR B CA    1 
ATOM 678  C C     . THR A 1 89  ? 105.157 144.441 117.850 1.00 34.20  ?  89  THR B C     1 
ATOM 679  O O     . THR A 1 89  ? 104.368 143.897 118.625 1.00 34.20  ?  89  THR B O     1 
ATOM 680  C CB    . THR A 1 89  ? 104.148 143.011 116.051 1.00 34.20  ?  89  THR B CB    1 
ATOM 681  O OG1   . THR A 1 89  ? 104.497 142.377 114.816 1.00 34.20  ?  89  THR B OG1   1 
ATOM 682  C CG2   . THR A 1 89  ? 102.755 143.608 115.925 1.00 34.20  ?  89  THR B CG2   1 
ATOM 683  N N     . LEU A 1 90  ? 106.070 145.322 118.271 1.00 29.37  ?  90  LEU B N     1 
ATOM 684  C CA    . LEU A 1 90  ? 106.133 145.780 119.658 1.00 29.37  ?  90  LEU B CA    1 
ATOM 685  C C     . LEU A 1 90  ? 104.746 146.089 120.200 1.00 29.37  ?  90  LEU B C     1 
ATOM 686  O O     . LEU A 1 90  ? 103.903 146.659 119.503 1.00 29.37  ?  90  LEU B O     1 
ATOM 687  C CB    . LEU A 1 90  ? 107.005 147.032 119.769 1.00 29.37  ?  90  LEU B CB    1 
ATOM 688  C CG    . LEU A 1 90  ? 108.231 147.150 118.872 1.00 29.37  ?  90  LEU B CG    1 
ATOM 689  C CD1   . LEU A 1 90  ? 108.787 148.556 118.945 1.00 29.37  ?  90  LEU B CD1   1 
ATOM 690  C CD2   . LEU A 1 90  ? 109.273 146.152 119.308 1.00 29.37  ?  90  LEU B CD2   1 
ATOM 691  N N     . ARG A 1 91  ? 104.514 145.709 121.454 1.00 37.18  ?  91  ARG B N     1 
ATOM 692  C CA    . ARG A 1 91  ? 103.200 145.891 122.055 1.00 37.18  ?  91  ARG B CA    1 
ATOM 693  C C     . ARG A 1 91  ? 103.336 145.907 123.568 1.00 37.18  ?  91  ARG B C     1 
ATOM 694  O O     . ARG A 1 91  ? 103.953 145.008 124.146 1.00 37.18  ?  91  ARG B O     1 
ATOM 695  C CB    . ARG A 1 91  ? 102.246 144.775 121.624 1.00 37.18  ?  91  ARG B CB    1 
ATOM 696  C CG    . ARG A 1 91  ? 100.994 144.659 122.471 1.00 37.18  ?  91  ARG B CG    1 
ATOM 697  C CD    . ARG A 1 91  ? 100.521 143.219 122.533 1.00 37.18  ?  91  ARG B CD    1 
ATOM 698  N NE    . ARG A 1 91  ? 100.724 142.527 121.266 1.00 37.18  ?  91  ARG B NE    1 
ATOM 699  C CZ    . ARG A 1 91  ? 99.863  142.530 120.259 1.00 37.18  ?  91  ARG B CZ    1 
ATOM 700  N NH1   . ARG A 1 91  ? 98.713  143.180 120.334 1.00 37.18  1  91  ARG B NH1   1 
ATOM 701  N NH2   . ARG A 1 91  ? 100.163 141.864 119.148 1.00 37.18  ?  91  ARG B NH2   1 
ATOM 702  N N     . ALA A 1 92  ? 102.759 146.924 124.197 1.00 46.71  ?  92  ALA B N     1 
ATOM 703  C CA    . ALA A 1 92  ? 102.625 146.997 125.643 1.00 46.71  ?  92  ALA B CA    1 
ATOM 704  C C     . ALA A 1 92  ? 101.156 147.210 125.963 1.00 46.71  ?  92  ALA B C     1 
ATOM 705  O O     . ALA A 1 92  ? 100.452 147.908 125.228 1.00 46.71  ?  92  ALA B O     1 
ATOM 706  C CB    . ALA A 1 92  ? 103.472 148.125 126.239 1.00 46.71  ?  92  ALA B CB    1 
ATOM 707  N N     . GLU A 1 93  ? 100.686 146.592 127.041 1.00 70.26  ?  93  GLU B N     1 
ATOM 708  C CA    . GLU A 1 93  ? 99.264  146.564 127.351 1.00 70.26  ?  93  GLU B CA    1 
ATOM 709  C C     . GLU A 1 93  ? 99.006  147.154 128.730 1.00 70.26  ?  93  GLU B C     1 
ATOM 710  O O     . GLU A 1 93  ? 99.603  146.717 129.719 1.00 70.26  ?  93  GLU B O     1 
ATOM 711  C CB    . GLU A 1 93  ? 98.722  145.135 127.281 1.00 70.26  ?  93  GLU B CB    1 
ATOM 712  C CG    . GLU A 1 93  ? 97.377  144.959 127.951 1.00 70.26  ?  93  GLU B CG    1 
ATOM 713  C CD    . GLU A 1 93  ? 96.278  145.706 127.225 1.00 70.26  ?  93  GLU B CD    1 
ATOM 714  O OE1   . GLU A 1 93  ? 96.036  146.885 127.560 1.00 70.26  ?  93  GLU B OE1   1 
ATOM 715  O OE2   . GLU A 1 93  ? 95.663  145.119 126.311 1.00 70.26  -1 93  GLU B OE2   1 
ATOM 716  N N     . ASP A 1 94  ? 98.108  148.140 128.783 1.00 84.62  ?  94  ASP B N     1 
ATOM 717  C CA    . ASP A 1 94  ? 97.561  148.721 130.019 1.00 84.62  ?  94  ASP B CA    1 
ATOM 718  C C     . ASP A 1 94  ? 98.734  149.179 130.889 1.00 84.62  ?  94  ASP B C     1 
ATOM 719  O O     . ASP A 1 94  ? 99.570  149.960 130.414 1.00 84.62  ?  94  ASP B O     1 
ATOM 720  C CB    . ASP A 1 94  ? 96.612  147.698 130.646 1.00 84.62  ?  94  ASP B CB    1 
ATOM 721  C CG    . ASP A 1 94  ? 96.006  148.166 131.965 1.00 84.62  ?  94  ASP B CG    1 
ATOM 722  O OD1   . ASP A 1 94  ? 96.328  149.280 132.429 1.00 84.62  ?  94  ASP B OD1   1 
ATOM 723  O OD2   . ASP A 1 94  ? 95.199  147.407 132.542 1.00 84.62  -1 94  ASP B OD2   1 
ATOM 724  N N     . ASN A 1 95  ? 98.837  148.736 132.140 1.00 95.86  ?  95  ASN B N     1 
ATOM 725  C CA    . ASN A 1 95  ? 99.867  149.182 133.071 1.00 95.86  ?  95  ASN B CA    1 
ATOM 726  C C     . ASN A 1 95  ? 100.719 148.015 133.558 1.00 95.86  ?  95  ASN B C     1 
ATOM 727  O O     . ASN A 1 95  ? 101.083 147.936 134.733 1.00 95.86  ?  95  ASN B O     1 
ATOM 728  C CB    . ASN A 1 95  ? 99.242  149.914 134.255 1.00 95.86  ?  95  ASN B CB    1 
ATOM 729  C CG    . ASN A 1 95  ? 100.179 150.934 134.873 1.00 95.86  ?  95  ASN B CG    1 
ATOM 730  O OD1   . ASN A 1 95  ? 101.395 150.743 134.900 1.00 95.86  ?  95  ASN B OD1   1 
ATOM 731  N ND2   . ASN A 1 95  ? 99.616  152.026 135.376 1.00 95.86  ?  95  ASN B ND2   1 
ATOM 732  N N     . ALA A 1 96  ? 101.042 147.092 132.659 1.00 91.14  ?  96  ALA B N     1 
ATOM 733  C CA    . ALA A 1 96  ? 101.926 145.984 132.991 1.00 91.14  ?  96  ALA B CA    1 
ATOM 734  C C     . ALA A 1 96  ? 103.373 146.471 132.941 1.00 91.14  ?  96  ALA B C     1 
ATOM 735  O O     . ALA A 1 96  ? 103.651 147.653 132.724 1.00 91.14  ?  96  ALA B O     1 
ATOM 736  C CB    . ALA A 1 96  ? 101.679 144.809 132.050 1.00 91.14  ?  96  ALA B CB    1 
ATOM 737  N N     . ASP A 1 97  ? 104.316 145.558 133.142 1.00 83.54  ?  97  ASP B N     1 
ATOM 738  C CA    . ASP A 1 97  ? 105.738 145.871 133.089 1.00 83.54  ?  97  ASP B CA    1 
ATOM 739  C C     . ASP A 1 97  ? 106.443 144.954 132.103 1.00 83.54  ?  97  ASP B C     1 
ATOM 740  O O     . ASP A 1 97  ? 107.588 144.542 132.312 1.00 83.54  ?  97  ASP B O     1 
ATOM 741  C CB    . ASP A 1 97  ? 106.373 145.771 134.473 1.00 83.54  ?  97  ASP B CB    1 
ATOM 742  C CG    . ASP A 1 97  ? 106.290 144.373 135.051 1.00 83.54  ?  97  ASP B CG    1 
ATOM 743  O OD1   . ASP A 1 97  ? 105.238 143.722 134.882 1.00 83.54  ?  97  ASP B OD1   1 
ATOM 744  O OD2   . ASP A 1 97  ? 107.278 143.925 135.670 1.00 83.54  -1 97  ASP B OD2   1 
ATOM 745  N N     . THR A 1 98  ? 105.766 144.622 131.008 1.00 65.16  ?  98  THR B N     1 
ATOM 746  C CA    . THR A 1 98  ? 106.275 143.670 130.033 1.00 65.16  ?  98  THR B CA    1 
ATOM 747  C C     . THR A 1 98  ? 106.220 144.280 128.642 1.00 65.16  ?  98  THR B C     1 
ATOM 748  O O     . THR A 1 98  ? 105.190 144.833 128.244 1.00 65.16  ?  98  THR B O     1 
ATOM 749  C CB    . THR A 1 98  ? 105.466 142.371 130.061 1.00 65.16  ?  98  THR B CB    1 
ATOM 750  O OG1   . THR A 1 98  ? 104.075 142.673 129.902 1.00 65.16  ?  98  THR B OG1   1 
ATOM 751  C CG2   . THR A 1 98  ? 105.671 141.645 131.381 1.00 65.16  ?  98  THR B CG2   1 
ATOM 752  N N     . LEU A 1 99  ? 107.324 144.176 127.911 1.00 47.83  ?  99  LEU B N     1 
ATOM 753  C CA    . LEU A 1 99  ? 107.379 144.556 126.506 1.00 47.83  ?  99  LEU B CA    1 
ATOM 754  C C     . LEU A 1 99  ? 107.249 143.292 125.667 1.00 47.83  ?  99  LEU B C     1 
ATOM 755  O O     . LEU A 1 99  ? 108.046 142.361 125.817 1.00 47.83  ?  99  LEU B O     1 
ATOM 756  C CB    . LEU A 1 99  ? 108.681 145.288 126.187 1.00 47.83  ?  99  LEU B CB    1 
ATOM 757  C CG    . LEU A 1 99  ? 108.662 146.230 124.984 1.00 47.83  ?  99  LEU B CG    1 
ATOM 758  C CD1   . LEU A 1 99  ? 107.357 147.003 124.924 1.00 47.83  ?  99  LEU B CD1   1 
ATOM 759  C CD2   . LEU A 1 99  ? 109.847 147.177 125.034 1.00 47.83  ?  99  LEU B CD2   1 
ATOM 760  N N     . ALA A 1 100 ? 106.249 143.257 124.795 1.00 35.90  ?  100 ALA B N     1 
ATOM 761  C CA    . ALA A 1 100 ? 105.918 142.062 124.024 1.00 35.90  ?  100 ALA B CA    1 
ATOM 762  C C     . ALA A 1 100 ? 106.358 142.274 122.578 1.00 35.90  ?  100 ALA B C     1 
ATOM 763  O O     . ALA A 1 100 ? 105.664 142.915 121.789 1.00 35.90  ?  100 ALA B O     1 
ATOM 764  C CB    . ALA A 1 100 ? 104.428 141.755 124.113 1.00 35.90  ?  100 ALA B CB    1 
ATOM 765  N N     . LEU A 1 101 ? 107.522 141.731 122.239 1.00 29.97  ?  101 LEU B N     1 
ATOM 766  C CA    . LEU A 1 101 ? 107.984 141.725 120.859 1.00 29.97  ?  101 LEU B CA    1 
ATOM 767  C C     . LEU A 1 101 ? 107.471 140.483 120.144 1.00 29.97  ?  101 LEU B C     1 
ATOM 768  O O     . LEU A 1 101 ? 107.502 139.378 120.692 1.00 29.97  ?  101 LEU B O     1 
ATOM 769  C CB    . LEU A 1 101 ? 109.509 141.764 120.805 1.00 29.97  ?  101 LEU B CB    1 
ATOM 770  C CG    . LEU A 1 101 ? 110.194 142.937 121.498 1.00 29.97  ?  101 LEU B CG    1 
ATOM 771  C CD1   . LEU A 1 101 ? 110.760 142.506 122.833 1.00 29.97  ?  101 LEU B CD1   1 
ATOM 772  C CD2   . LEU A 1 101 ? 111.292 143.483 120.616 1.00 29.97  ?  101 LEU B CD2   1 
ATOM 773  N N     . VAL A 1 102 ? 106.994 140.666 118.917 1.00 54.26  ?  102 VAL B N     1 
ATOM 774  C CA    . VAL A 1 102 ? 106.475 139.571 118.106 1.00 54.26  ?  102 VAL B CA    1 
ATOM 775  C C     . VAL A 1 102 ? 107.129 139.644 116.736 1.00 54.26  ?  102 VAL B C     1 
ATOM 776  O O     . VAL A 1 102 ? 107.024 140.667 116.051 1.00 54.26  ?  102 VAL B O     1 
ATOM 777  C CB    . VAL A 1 102 ? 104.945 139.626 117.976 1.00 54.26  ?  102 VAL B CB    1 
ATOM 778  C CG1   . VAL A 1 102 ? 104.468 138.610 116.956 1.00 54.26  ?  102 VAL B CG1   1 
ATOM 779  C CG2   . VAL A 1 102 ? 104.290 139.384 119.322 1.00 54.26  ?  102 VAL B CG2   1 
ATOM 780  N N     . PHE A 1 103 ? 107.794 138.565 116.334 1.00 39.00  ?  103 PHE B N     1 
ATOM 781  C CA    . PHE A 1 103 ? 108.418 138.467 115.022 1.00 39.00  ?  103 PHE B CA    1 
ATOM 782  C C     . PHE A 1 103 ? 107.637 137.472 114.179 1.00 39.00  ?  103 PHE B C     1 
ATOM 783  O O     . PHE A 1 103 ? 107.389 136.345 114.616 1.00 39.00  ?  103 PHE B O     1 
ATOM 784  C CB    . PHE A 1 103 ? 109.879 138.021 115.121 1.00 39.00  ?  103 PHE B CB    1 
ATOM 785  C CG    . PHE A 1 103 ? 110.664 138.710 116.200 1.00 39.00  ?  103 PHE B CG    1 
ATOM 786  C CD1   . PHE A 1 103 ? 110.436 140.036 116.513 1.00 39.00  ?  103 PHE B CD1   1 
ATOM 787  C CD2   . PHE A 1 103 ? 111.645 138.027 116.894 1.00 39.00  ?  103 PHE B CD2   1 
ATOM 788  C CE1   . PHE A 1 103 ? 111.163 140.661 117.501 1.00 39.00  ?  103 PHE B CE1   1 
ATOM 789  C CE2   . PHE A 1 103 ? 112.374 138.649 117.882 1.00 39.00  ?  103 PHE B CE2   1 
ATOM 790  C CZ    . PHE A 1 103 ? 112.133 139.967 118.186 1.00 39.00  ?  103 PHE B CZ    1 
ATOM 791  N N     . GLU A 1 104 ? 107.256 137.884 112.975 1.00 49.53  ?  104 GLU B N     1 
ATOM 792  C CA    . GLU A 1 104 ? 106.529 137.028 112.050 1.00 49.53  ?  104 GLU B CA    1 
ATOM 793  C C     . GLU A 1 104 ? 107.348 136.850 110.783 1.00 49.53  ?  104 GLU B C     1 
ATOM 794  O O     . GLU A 1 104 ? 107.737 137.836 110.149 1.00 49.53  ?  104 GLU B O     1 
ATOM 795  C CB    . GLU A 1 104 ? 105.157 137.616 111.713 1.00 49.53  ?  104 GLU B CB    1 
ATOM 796  C CG    . GLU A 1 104 ? 104.361 138.065 112.923 1.00 49.53  ?  104 GLU B CG    1 
ATOM 797  C CD    . GLU A 1 104 ? 103.155 138.900 112.545 1.00 49.53  ?  104 GLU B CD    1 
ATOM 798  O OE1   . GLU A 1 104 ? 103.027 139.255 111.355 1.00 49.53  ?  104 GLU B OE1   1 
ATOM 799  O OE2   . GLU A 1 104 ? 102.336 139.204 113.436 1.00 49.53  -1 104 GLU B OE2   1 
ATOM 800  N N     . ALA A 1 105 ? 107.608 135.600 110.419 1.00 58.41  ?  105 ALA B N     1 
ATOM 801  C CA    . ALA A 1 105 ? 108.312 135.327 109.181 1.00 58.41  ?  105 ALA B CA    1 
ATOM 802  C C     . ALA A 1 105 ? 107.425 135.681 107.988 1.00 58.41  ?  105 ALA B C     1 
ATOM 803  O O     . ALA A 1 105 ? 106.201 135.548 108.055 1.00 58.41  ?  105 ALA B O     1 
ATOM 804  C CB    . ALA A 1 105 ? 108.727 133.862 109.111 1.00 58.41  ?  105 ALA B CB    1 
ATOM 805  N N     . PRO A 1 106 ? 108.019 136.149 106.888 1.00 65.27  ?  106 PRO B N     1 
ATOM 806  C CA    . PRO A 1 106 ? 107.206 136.532 105.721 1.00 65.27  ?  106 PRO B CA    1 
ATOM 807  C C     . PRO A 1 106 ? 106.392 135.392 105.136 1.00 65.27  ?  106 PRO B C     1 
ATOM 808  O O     . PRO A 1 106 ? 105.311 135.643 104.590 1.00 65.27  ?  106 PRO B O     1 
ATOM 809  C CB    . PRO A 1 106 ? 108.247 137.048 104.717 1.00 65.27  ?  106 PRO B CB    1 
ATOM 810  C CG    . PRO A 1 106 ? 109.456 137.361 105.533 1.00 65.27  ?  106 PRO B CG    1 
ATOM 811  C CD    . PRO A 1 106 ? 109.454 136.388 106.665 1.00 65.27  ?  106 PRO B CD    1 
ATOM 812  N N     . ASN A 1 107 ? 106.867 134.153 105.231 1.00 66.47  ?  107 ASN B N     1 
ATOM 813  C CA    . ASN A 1 107 ? 106.160 133.007 104.677 1.00 66.47  ?  107 ASN B CA    1 
ATOM 814  C C     . ASN A 1 107 ? 105.093 132.457 105.617 1.00 66.47  ?  107 ASN B C     1 
ATOM 815  O O     . ASN A 1 107 ? 104.605 131.346 105.386 1.00 66.47  ?  107 ASN B O     1 
ATOM 816  C CB    . ASN A 1 107 ? 107.153 131.899 104.317 1.00 66.47  ?  107 ASN B CB    1 
ATOM 817  C CG    . ASN A 1 107 ? 107.960 131.428 105.510 1.00 66.47  ?  107 ASN B CG    1 
ATOM 818  O OD1   . ASN A 1 107 ? 107.869 131.992 106.599 1.00 66.47  ?  107 ASN B OD1   1 
ATOM 819  N ND2   . ASN A 1 107 ? 108.755 130.384 105.310 1.00 66.47  ?  107 ASN B ND2   1 
ATOM 820  N N     . GLN A 1 108 ? 104.688 133.234 106.628 1.00 65.49  ?  108 GLN B N     1 
ATOM 821  C CA    . GLN A 1 108 ? 103.789 132.801 107.697 1.00 65.49  ?  108 GLN B CA    1 
ATOM 822  C C     . GLN A 1 108 ? 103.976 131.332 108.063 1.00 65.49  ?  108 GLN B C     1 
ATOM 823  O O     . GLN A 1 108 ? 103.031 130.541 107.983 1.00 65.49  ?  108 GLN B O     1 
ATOM 824  C CB    . GLN A 1 108 ? 102.298 133.077 107.406 1.00 65.49  ?  108 GLN B CB    1 
ATOM 825  C CG    . GLN A 1 108 ? 101.857 134.328 106.598 1.00 65.49  ?  108 GLN B CG    1 
ATOM 826  C CD    . GLN A 1 108 ? 102.083 134.308 105.091 1.00 65.49  ?  108 GLN B CD    1 
ATOM 827  O OE1   . GLN A 1 108 ? 103.013 133.708 104.580 1.00 65.49  ?  108 GLN B OE1   1 
ATOM 828  N NE2   . GLN A 1 108 ? 101.198 134.986 104.371 1.00 65.49  ?  108 GLN B NE2   1 
ATOM 829  N N     . GLU A 1 109 ? 105.192 130.959 108.463 1.00 57.43  ?  109 GLU B N     1 
ATOM 830  C CA    . GLU A 1 109 ? 105.469 129.602 108.905 1.00 57.43  ?  109 GLU B CA    1 
ATOM 831  C C     . GLU A 1 109 ? 106.190 129.536 110.243 1.00 57.43  ?  109 GLU B C     1 
ATOM 832  O O     . GLU A 1 109 ? 106.403 128.433 110.755 1.00 57.43  ?  109 GLU B O     1 
ATOM 833  C CB    . GLU A 1 109 ? 106.297 128.848 107.854 1.00 57.43  ?  109 GLU B CB    1 
ATOM 834  C CG    . GLU A 1 109 ? 105.555 128.576 106.558 1.00 57.43  ?  109 GLU B CG    1 
ATOM 835  C CD    . GLU A 1 109 ? 104.462 127.537 106.716 1.00 57.43  ?  109 GLU B CD    1 
ATOM 836  O OE1   . GLU A 1 109 ? 104.516 126.756 107.689 1.00 57.43  ?  109 GLU B OE1   1 
ATOM 837  O OE2   . GLU A 1 109 ? 103.546 127.503 105.868 1.00 57.43  -1 109 GLU B OE2   1 
ATOM 838  N N     . LYS A 1 110 ? 106.568 130.672 110.823 1.00 36.95  ?  110 LYS B N     1 
ATOM 839  C CA    . LYS A 1 110 ? 107.304 130.666 112.084 1.00 36.95  ?  110 LYS B CA    1 
ATOM 840  C C     . LYS A 1 110 ? 107.052 131.992 112.785 1.00 36.95  ?  110 LYS B C     1 
ATOM 841  O O     . LYS A 1 110 ? 107.550 133.030 112.340 1.00 36.95  ?  110 LYS B O     1 
ATOM 842  C CB    . LYS A 1 110 ? 108.789 130.444 111.839 1.00 36.95  ?  110 LYS B CB    1 
ATOM 843  C CG    . LYS A 1 110 ? 109.649 130.597 113.072 1.00 36.95  ?  110 LYS B CG    1 
ATOM 844  C CD    . LYS A 1 110 ? 111.097 130.283 112.763 1.00 36.95  ?  110 LYS B CD    1 
ATOM 845  C CE    . LYS A 1 110 ? 111.994 130.653 113.924 1.00 36.95  ?  110 LYS B CE    1 
ATOM 846  N NZ    . LYS A 1 110 ? 113.430 130.519 113.573 1.00 36.95  1  110 LYS B NZ    1 
ATOM 847  N N     . VAL A 1 111 ? 106.289 131.956 113.872 1.00 31.57  ?  111 VAL B N     1 
ATOM 848  C CA    . VAL A 1 111 ? 105.924 133.147 114.628 1.00 31.57  ?  111 VAL B CA    1 
ATOM 849  C C     . VAL A 1 111 ? 106.638 133.089 115.969 1.00 31.57  ?  111 VAL B C     1 
ATOM 850  O O     . VAL A 1 111 ? 106.429 132.155 116.751 1.00 31.57  ?  111 VAL B O     1 
ATOM 851  C CB    . VAL A 1 111 ? 104.405 133.249 114.821 1.00 31.57  ?  111 VAL B CB    1 
ATOM 852  C CG1   . VAL A 1 111 ? 104.055 134.512 115.583 1.00 31.57  ?  111 VAL B CG1   1 
ATOM 853  C CG2   . VAL A 1 111 ? 103.700 133.211 113.479 1.00 31.57  ?  111 VAL B CG2   1 
ATOM 854  N N     . SER A 1 112 ? 107.473 134.085 116.239 1.00 29.07  ?  112 SER B N     1 
ATOM 855  C CA    . SER A 1 112 ? 108.221 134.169 117.484 1.00 29.07  ?  112 SER B CA    1 
ATOM 856  C C     . SER A 1 112 ? 107.602 135.239 118.369 1.00 29.07  ?  112 SER B C     1 
ATOM 857  O O     . SER A 1 112 ? 107.355 136.359 117.913 1.00 29.07  ?  112 SER B O     1 
ATOM 858  C CB    . SER A 1 112 ? 109.692 134.489 117.220 1.00 29.07  ?  112 SER B CB    1 
ATOM 859  O OG    . SER A 1 112 ? 110.256 133.567 116.307 1.00 29.07  ?  112 SER B OG    1 
ATOM 860  N N     . ASP A 1 113 ? 107.349 134.892 119.626 1.00 28.55  ?  113 ASP B N     1 
ATOM 861  C CA    . ASP A 1 113 ? 106.777 135.814 120.598 1.00 28.55  ?  113 ASP B CA    1 
ATOM 862  C C     . ASP A 1 113 ? 107.713 135.892 121.792 1.00 28.55  ?  113 ASP B C     1 
ATOM 863  O O     . ASP A 1 113 ? 108.035 134.866 122.398 1.00 28.55  ?  113 ASP B O     1 
ATOM 864  C CB    . ASP A 1 113 ? 105.380 135.358 121.027 1.00 28.55  ?  113 ASP B CB    1 
ATOM 865  C CG    . ASP A 1 113 ? 104.737 136.293 122.037 1.00 28.55  ?  113 ASP B CG    1 
ATOM 866  O OD1   . ASP A 1 113 ? 105.239 136.397 123.176 1.00 28.55  ?  113 ASP B OD1   1 
ATOM 867  O OD2   . ASP A 1 113 ? 103.719 136.927 121.690 1.00 28.55  -1 113 ASP B OD2   1 
ATOM 868  N N     . TYR A 1 114 ? 108.144 137.102 122.132 1.00 30.26  ?  114 TYR B N     1 
ATOM 869  C CA    . TYR A 1 114 ? 109.022 137.329 123.267 1.00 30.26  ?  114 TYR B CA    1 
ATOM 870  C C     . TYR A 1 114 ? 108.381 138.332 124.214 1.00 30.26  ?  114 TYR B C     1 
ATOM 871  O O     . TYR A 1 114 ? 107.556 139.154 123.808 1.00 30.26  ?  114 TYR B O     1 
ATOM 872  C CB    . TYR A 1 114 ? 110.400 137.844 122.836 1.00 30.26  ?  114 TYR B CB    1 
ATOM 873  C CG    . TYR A 1 114 ? 111.234 136.859 122.049 1.00 30.26  ?  114 TYR B CG    1 
ATOM 874  C CD1   . TYR A 1 114 ? 110.795 136.351 120.835 1.00 30.26  ?  114 TYR B CD1   1 
ATOM 875  C CD2   . TYR A 1 114 ? 112.465 136.434 122.525 1.00 30.26  ?  114 TYR B CD2   1 
ATOM 876  C CE1   . TYR A 1 114 ? 111.556 135.453 120.120 1.00 30.26  ?  114 TYR B CE1   1 
ATOM 877  C CE2   . TYR A 1 114 ? 113.233 135.536 121.817 1.00 30.26  ?  114 TYR B CE2   1 
ATOM 878  C CZ    . TYR A 1 114 ? 112.774 135.050 120.616 1.00 30.26  ?  114 TYR B CZ    1 
ATOM 879  O OH    . TYR A 1 114 ? 113.538 134.154 119.907 1.00 30.26  ?  114 TYR B OH    1 
ATOM 880  N N     . GLU A 1 115 ? 108.765 138.256 125.484 1.00 41.29  ?  115 GLU B N     1 
ATOM 881  C CA    . GLU A 1 115 ? 108.230 139.146 126.502 1.00 41.29  ?  115 GLU B CA    1 
ATOM 882  C C     . GLU A 1 115 ? 109.365 139.633 127.387 1.00 41.29  ?  115 GLU B C     1 
ATOM 883  O O     . GLU A 1 115 ? 110.230 138.851 127.788 1.00 41.29  ?  115 GLU B O     1 
ATOM 884  C CB    . GLU A 1 115 ? 107.158 138.446 127.343 1.00 41.29  ?  115 GLU B CB    1 
ATOM 885  C CG    . GLU A 1 115 ? 106.734 139.216 128.578 1.00 41.29  ?  115 GLU B CG    1 
ATOM 886  C CD    . GLU A 1 115 ? 105.526 138.605 129.256 1.00 41.29  ?  115 GLU B CD    1 
ATOM 887  O OE1   . GLU A 1 115 ? 104.545 138.288 128.551 1.00 41.29  ?  115 GLU B OE1   1 
ATOM 888  O OE2   . GLU A 1 115 ? 105.556 138.441 130.494 1.00 41.29  -1 115 GLU B OE2   1 
ATOM 889  N N     . MET A 1 116 ? 109.356 140.927 127.686 1.00 54.54  ?  116 MET B N     1 
ATOM 890  C CA    . MET A 1 116 ? 110.387 141.555 128.491 1.00 54.54  ?  116 MET B CA    1 
ATOM 891  C C     . MET A 1 116 ? 109.874 141.869 129.892 1.00 54.54  ?  116 MET B C     1 
ATOM 892  O O     . MET A 1 116 ? 108.743 141.551 130.263 1.00 54.54  ?  116 MET B O     1 
ATOM 893  C CB    . MET A 1 116 ? 110.890 142.829 127.816 1.00 54.54  ?  116 MET B CB    1 
ATOM 894  C CG    . MET A 1 116 ? 112.390 142.946 127.788 1.00 54.54  ?  116 MET B CG    1 
ATOM 895  S SD    . MET A 1 116 ? 112.969 144.046 126.496 1.00 54.54  ?  116 MET B SD    1 
ATOM 896  C CE    . MET A 1 116 ? 114.724 143.943 126.798 1.00 54.54  ?  116 MET B CE    1 
ATOM 897  N N     . LYS A 1 117 ? 110.736 142.510 130.680 1.00 67.90  ?  117 LYS B N     1 
ATOM 898  C CA    . LYS A 1 117 ? 110.395 142.981 132.016 1.00 67.90  ?  117 LYS B CA    1 
ATOM 899  C C     . LYS A 1 117 ? 110.842 144.429 132.138 1.00 67.90  ?  117 LYS B C     1 
ATOM 900  O O     . LYS A 1 117 ? 112.043 144.715 132.104 1.00 67.90  ?  117 LYS B O     1 
ATOM 901  C CB    . LYS A 1 117 ? 111.053 142.119 133.096 1.00 67.90  ?  117 LYS B CB    1 
ATOM 902  C CG    . LYS A 1 117 ? 112.337 141.443 132.653 1.00 67.90  ?  117 LYS B CG    1 
ATOM 903  C CD    . LYS A 1 117 ? 113.024 140.754 133.819 1.00 67.90  ?  117 LYS B CD    1 
ATOM 904  C CE    . LYS A 1 117 ? 112.097 139.762 134.501 1.00 67.90  ?  117 LYS B CE    1 
ATOM 905  N NZ    . LYS A 1 117 ? 112.820 138.926 135.498 1.00 67.90  1  117 LYS B NZ    1 
ATOM 906  N N     . LEU A 1 118 ? 109.880 145.335 132.275 1.00 77.60  ?  118 LEU B N     1 
ATOM 907  C CA    . LEU A 1 118 ? 110.187 146.753 132.369 1.00 77.60  ?  118 LEU B CA    1 
ATOM 908  C C     . LEU A 1 118 ? 110.836 147.078 133.711 1.00 77.60  ?  118 LEU B C     1 
ATOM 909  O O     . LEU A 1 118 ? 110.744 146.320 134.681 1.00 77.60  ?  118 LEU B O     1 
ATOM 910  C CB    . LEU A 1 118 ? 108.920 147.589 132.197 1.00 77.60  ?  118 LEU B CB    1 
ATOM 911  C CG    . LEU A 1 118 ? 108.522 148.055 130.796 1.00 77.60  ?  118 LEU B CG    1 
ATOM 912  C CD1   . LEU A 1 118 ? 108.631 146.930 129.784 1.00 77.60  ?  118 LEU B CD1   1 
ATOM 913  C CD2   . LEU A 1 118 ? 107.110 148.610 130.825 1.00 77.60  ?  118 LEU B CD2   1 
ATOM 914  N N     . MET A 1 119 ? 111.505 148.227 133.756 1.00 91.74  ?  119 MET B N     1 
ATOM 915  C CA    . MET A 1 119 ? 112.073 148.749 134.988 1.00 91.74  ?  119 MET B CA    1 
ATOM 916  C C     . MET A 1 119 ? 111.791 150.242 135.059 1.00 91.74  ?  119 MET B C     1 
ATOM 917  O O     . MET A 1 119 ? 111.521 150.891 134.046 1.00 91.74  ?  119 MET B O     1 
ATOM 918  C CB    . MET A 1 119 ? 113.581 148.477 135.087 1.00 91.74  ?  119 MET B CB    1 
ATOM 919  C CG    . MET A 1 119 ? 114.439 149.399 134.243 1.00 91.74  ?  119 MET B CG    1 
ATOM 920  S SD    . MET A 1 119 ? 116.182 148.937 134.254 1.00 91.74  ?  119 MET B SD    1 
ATOM 921  C CE    . MET A 1 119 ? 116.060 147.151 134.259 1.00 91.74  ?  119 MET B CE    1 
ATOM 922  N N     . ASP A 1 120 ? 111.845 150.782 136.273 1.00 107.19 ?  120 ASP B N     1 
ATOM 923  C CA    . ASP A 1 120 ? 111.521 152.183 136.508 1.00 107.19 ?  120 ASP B CA    1 
ATOM 924  C C     . ASP A 1 120 ? 112.788 153.025 136.429 1.00 107.19 ?  120 ASP B C     1 
ATOM 925  O O     . ASP A 1 120 ? 113.749 152.785 137.168 1.00 107.19 ?  120 ASP B O     1 
ATOM 926  C CB    . ASP A 1 120 ? 110.843 152.361 137.866 1.00 107.19 ?  120 ASP B CB    1 
ATOM 927  C CG    . ASP A 1 120 ? 110.160 153.708 138.003 1.00 107.19 ?  120 ASP B CG    1 
ATOM 928  O OD1   . ASP A 1 120 ? 110.200 154.498 137.036 1.00 107.19 ?  120 ASP B OD1   1 
ATOM 929  O OD2   . ASP A 1 120 ? 109.584 153.976 139.077 1.00 107.19 -1 120 ASP B OD2   1 
ATOM 930  N N     . LEU A 1 121 ? 112.783 154.012 135.538 1.00 111.27 ?  121 LEU B N     1 
ATOM 931  C CA    . LEU A 1 121 ? 113.886 154.945 135.371 1.00 111.27 ?  121 LEU B CA    1 
ATOM 932  C C     . LEU A 1 121 ? 113.386 156.364 135.596 1.00 111.27 ?  121 LEU B C     1 
ATOM 933  O O     . LEU A 1 121 ? 112.278 156.715 135.179 1.00 111.27 ?  121 LEU B O     1 
ATOM 934  C CB    . LEU A 1 121 ? 114.511 154.831 133.975 1.00 111.27 ?  121 LEU B CB    1 
ATOM 935  C CG    . LEU A 1 121 ? 115.822 154.052 133.838 1.00 111.27 ?  121 LEU B CG    1 
ATOM 936  C CD1   . LEU A 1 121 ? 116.998 154.910 134.275 1.00 111.27 ?  121 LEU B CD1   1 
ATOM 937  C CD2   . LEU A 1 121 ? 115.781 152.757 134.627 1.00 111.27 ?  121 LEU B CD2   1 
ATOM 938  N N     . ASP A 1 122 ? 114.205 157.174 136.263 1.00 117.89 ?  122 ASP B N     1 
ATOM 939  C CA    . ASP A 1 122 ? 113.851 158.567 136.494 1.00 117.89 ?  122 ASP B CA    1 
ATOM 940  C C     . ASP A 1 122 ? 113.822 159.332 135.177 1.00 117.89 ?  122 ASP B C     1 
ATOM 941  O O     . ASP A 1 122 ? 114.736 159.225 134.355 1.00 117.89 ?  122 ASP B O     1 
ATOM 942  C CB    . ASP A 1 122 ? 114.843 159.214 137.460 1.00 117.89 ?  122 ASP B CB    1 
ATOM 943  C CG    . ASP A 1 122 ? 116.285 159.002 137.044 1.00 117.89 ?  122 ASP B CG    1 
ATOM 944  O OD1   . ASP A 1 122 ? 116.782 159.774 136.197 1.00 117.89 ?  122 ASP B OD1   1 
ATOM 945  O OD2   . ASP A 1 122 ? 116.922 158.061 137.562 1.00 117.89 -1 122 ASP B OD2   1 
ATOM 946  N N     . VAL A 1 123 ? 112.760 160.109 134.978 1.00 111.95 ?  123 VAL B N     1 
ATOM 947  C CA    . VAL A 1 123 ? 112.566 160.863 133.745 1.00 111.95 ?  123 VAL B CA    1 
ATOM 948  C C     . VAL A 1 123 ? 113.370 162.153 133.873 1.00 111.95 ?  123 VAL B C     1 
ATOM 949  O O     . VAL A 1 123 ? 112.906 163.139 134.448 1.00 111.95 ?  123 VAL B O     1 
ATOM 950  C CB    . VAL A 1 123 ? 111.086 161.136 133.471 1.00 111.95 ?  123 VAL B CB    1 
ATOM 951  C CG1   . VAL A 1 123 ? 110.924 161.972 132.209 1.00 111.95 ?  123 VAL B CG1   1 
ATOM 952  C CG2   . VAL A 1 123 ? 110.324 159.827 133.344 1.00 111.95 ?  123 VAL B CG2   1 
ATOM 953  N N     . GLU A 1 124 ? 114.588 162.140 133.339 1.00 118.18 ?  124 GLU B N     1 
ATOM 954  C CA    . GLU A 1 124 ? 115.457 163.309 133.326 1.00 118.18 ?  124 GLU B CA    1 
ATOM 955  C C     . GLU A 1 124 ? 115.408 163.938 131.940 1.00 118.18 ?  124 GLU B C     1 
ATOM 956  O O     . GLU A 1 124 ? 115.716 163.276 130.942 1.00 118.18 ?  124 GLU B O     1 
ATOM 957  C CB    . GLU A 1 124 ? 116.890 162.929 133.695 1.00 118.18 ?  124 GLU B CB    1 
ATOM 958  C CG    . GLU A 1 124 ? 117.168 162.921 135.187 1.00 118.18 ?  124 GLU B CG    1 
ATOM 959  C CD    . GLU A 1 124 ? 118.621 162.629 135.504 1.00 118.18 ?  124 GLU B CD    1 
ATOM 960  O OE1   . GLU A 1 124 ? 119.418 162.479 134.554 1.00 118.18 ?  124 GLU B OE1   1 
ATOM 961  O OE2   . GLU A 1 124 ? 118.965 162.551 136.701 1.00 118.18 -1 124 GLU B OE2   1 
ATOM 962  N N     . GLN A 1 125 ? 115.022 165.208 131.879 1.00 113.29 ?  125 GLN B N     1 
ATOM 963  C CA    . GLN A 1 125 ? 114.913 165.938 130.625 1.00 113.29 ?  125 GLN B CA    1 
ATOM 964  C C     . GLN A 1 125 ? 116.053 166.941 130.531 1.00 113.29 ?  125 GLN B C     1 
ATOM 965  O O     . GLN A 1 125 ? 116.287 167.712 131.467 1.00 113.29 ?  125 GLN B O     1 
ATOM 966  C CB    . GLN A 1 125 ? 113.561 166.651 130.520 1.00 113.29 ?  125 GLN B CB    1 
ATOM 967  C CG    . GLN A 1 125 ? 113.111 166.954 129.094 1.00 113.29 ?  125 GLN B CG    1 
ATOM 968  C CD    . GLN A 1 125 ? 113.900 168.075 128.442 1.00 113.29 ?  125 GLN B CD    1 
ATOM 969  O OE1   . GLN A 1 125 ? 114.396 168.977 129.117 1.00 113.29 ?  125 GLN B OE1   1 
ATOM 970  N NE2   . GLN A 1 125 ? 114.020 168.022 127.121 1.00 113.29 ?  125 GLN B NE2   1 
ATOM 971  N N     . LEU A 1 126 ? 116.758 166.924 129.405 1.00 105.08 ?  126 LEU B N     1 
ATOM 972  C CA    . LEU A 1 126 ? 117.850 167.847 129.138 1.00 105.08 ?  126 LEU B CA    1 
ATOM 973  C C     . LEU A 1 126 ? 117.454 168.764 127.989 1.00 105.08 ?  126 LEU B C     1 
ATOM 974  O O     . LEU A 1 126 ? 117.049 168.290 126.923 1.00 105.08 ?  126 LEU B O     1 
ATOM 975  C CB    . LEU A 1 126 ? 119.135 167.088 128.805 1.00 105.08 ?  126 LEU B CB    1 
ATOM 976  C CG    . LEU A 1 126 ? 119.647 166.167 129.914 1.00 105.08 ?  126 LEU B CG    1 
ATOM 977  C CD1   . LEU A 1 126 ? 119.955 164.781 129.372 1.00 105.08 ?  126 LEU B CD1   1 
ATOM 978  C CD2   . LEU A 1 126 ? 120.871 166.768 130.585 1.00 105.08 ?  126 LEU B CD2   1 
ATOM 979  N N     . GLY A 1 127 ? 117.563 170.071 128.214 1.00 112.10 ?  127 GLY B N     1 
ATOM 980  C CA    . GLY A 1 127 ? 117.143 171.028 127.206 1.00 112.10 ?  127 GLY B CA    1 
ATOM 981  C C     . GLY A 1 127 ? 117.999 170.947 125.953 1.00 112.10 ?  127 GLY B C     1 
ATOM 982  O O     . GLY A 1 127 ? 119.222 170.816 126.015 1.00 112.10 ?  127 GLY B O     1 
ATOM 983  N N     . ILE A 1 128 ? 117.339 171.029 124.803 1.00 105.45 ?  128 ILE B N     1 
ATOM 984  C CA    . ILE A 1 128 ? 118.016 171.005 123.509 1.00 105.45 ?  128 ILE B CA    1 
ATOM 985  C C     . ILE A 1 128 ? 117.683 172.292 122.764 1.00 105.45 ?  128 ILE B C     1 
ATOM 986  O O     . ILE A 1 128 ? 116.667 172.353 122.058 1.00 105.45 ?  128 ILE B O     1 
ATOM 987  C CB    . ILE A 1 128 ? 117.615 169.772 122.685 1.00 105.45 ?  128 ILE B CB    1 
ATOM 988  C CG1   . ILE A 1 128 ? 117.665 168.511 123.548 1.00 105.45 ?  128 ILE B CG1   1 
ATOM 989  C CG2   . ILE A 1 128 ? 118.519 169.628 121.473 1.00 105.45 ?  128 ILE B CG2   1 
ATOM 990  C CD1   . ILE A 1 128 ? 119.044 168.186 124.071 1.00 105.45 ?  128 ILE B CD1   1 
ATOM 991  N N     . PRO A 1 129 ? 118.499 173.336 122.886 1.00 115.00 ?  129 PRO B N     1 
ATOM 992  C CA    . PRO A 1 129 ? 118.181 174.600 122.212 1.00 115.00 ?  129 PRO B CA    1 
ATOM 993  C C     . PRO A 1 129 ? 118.664 174.631 120.771 1.00 115.00 ?  129 PRO B C     1 
ATOM 994  O O     . PRO A 1 129 ? 119.840 174.371 120.495 1.00 115.00 ?  129 PRO B O     1 
ATOM 995  C CB    . PRO A 1 129 ? 118.901 175.646 123.071 1.00 115.00 ?  129 PRO B CB    1 
ATOM 996  C CG    . PRO A 1 129 ? 119.980 174.887 123.813 1.00 115.00 ?  129 PRO B CG    1 
ATOM 997  C CD    . PRO A 1 129 ? 119.765 173.407 123.632 1.00 115.00 ?  129 PRO B CD    1 
ATOM 998  N N     . GLU A 1 130 ? 117.761 174.946 119.847 1.00 121.01 ?  130 GLU B N     1 
ATOM 999  C CA    . GLU A 1 130 ? 118.131 175.062 118.444 1.00 121.01 ?  130 GLU B CA    1 
ATOM 1000 C C     . GLU A 1 130 ? 119.018 176.282 118.230 1.00 121.01 ?  130 GLU B C     1 
ATOM 1001 O O     . GLU A 1 130 ? 118.814 177.334 118.842 1.00 121.01 ?  130 GLU B O     1 
ATOM 1002 C CB    . GLU A 1 130 ? 116.882 175.159 117.569 1.00 121.01 ?  130 GLU B CB    1 
ATOM 1003 C CG    . GLU A 1 130 ? 116.038 173.892 117.533 1.00 121.01 ?  130 GLU B CG    1 
ATOM 1004 C CD    . GLU A 1 130 ? 115.195 173.712 118.781 1.00 121.01 ?  130 GLU B CD    1 
ATOM 1005 O OE1   . GLU A 1 130 ? 115.031 174.694 119.535 1.00 121.01 ?  130 GLU B OE1   1 
ATOM 1006 O OE2   . GLU A 1 130 ? 114.697 172.589 119.007 1.00 121.01 -1 130 GLU B OE2   1 
ATOM 1007 N N     . GLN A 1 131 ? 120.010 176.137 117.356 1.00 97.54  ?  131 GLN B N     1 
ATOM 1008 C CA    . GLN A 1 131 ? 120.974 177.198 117.110 1.00 97.54  ?  131 GLN B CA    1 
ATOM 1009 C C     . GLN A 1 131 ? 121.504 177.063 115.689 1.00 97.54  ?  131 GLN B C     1 
ATOM 1010 O O     . GLN A 1 131 ? 121.085 176.188 114.927 1.00 97.54  ?  131 GLN B O     1 
ATOM 1011 C CB    . GLN A 1 131 ? 122.102 177.152 118.142 1.00 97.54  ?  131 GLN B CB    1 
ATOM 1012 C CG    . GLN A 1 131 ? 122.599 175.751 118.433 1.00 97.54  ?  131 GLN B CG    1 
ATOM 1013 C CD    . GLN A 1 131 ? 123.242 175.637 119.797 1.00 97.54  ?  131 GLN B CD    1 
ATOM 1014 O OE1   . GLN A 1 131 ? 124.326 176.167 120.030 1.00 97.54  ?  131 GLN B OE1   1 
ATOM 1015 N NE2   . GLN A 1 131 ? 122.573 174.942 120.709 1.00 97.54  ?  131 GLN B NE2   1 
ATOM 1016 N N     . GLU A 1 132 ? 122.435 177.945 115.336 1.00 82.47  ?  132 GLU B N     1 
ATOM 1017 C CA    . GLU A 1 132 ? 123.037 177.976 114.012 1.00 82.47  ?  132 GLU B CA    1 
ATOM 1018 C C     . GLU A 1 132 ? 124.495 177.546 114.097 1.00 82.47  ?  132 GLU B C     1 
ATOM 1019 O O     . GLU A 1 132 ? 125.229 177.979 114.991 1.00 82.47  ?  132 GLU B O     1 
ATOM 1020 C CB    . GLU A 1 132 ? 122.937 179.373 113.396 1.00 82.47  ?  132 GLU B CB    1 
ATOM 1021 C CG    . GLU A 1 132 ? 121.533 179.760 112.965 1.00 82.47  ?  132 GLU B CG    1 
ATOM 1022 C CD    . GLU A 1 132 ? 120.785 178.612 112.318 1.00 82.47  ?  132 GLU B CD    1 
ATOM 1023 O OE1   . GLU A 1 132 ? 121.027 178.340 111.124 1.00 82.47  ?  132 GLU B OE1   1 
ATOM 1024 O OE2   . GLU A 1 132 ? 119.950 177.983 113.002 1.00 82.47  -1 132 GLU B OE2   1 
ATOM 1025 N N     . TYR A 1 133 ? 124.909 176.696 113.165 1.00 64.64  ?  133 TYR B N     1 
ATOM 1026 C CA    . TYR A 1 133 ? 126.249 176.134 113.158 1.00 64.64  ?  133 TYR B CA    1 
ATOM 1027 C C     . TYR A 1 133 ? 127.103 176.773 112.069 1.00 64.64  ?  133 TYR B C     1 
ATOM 1028 O O     . TYR A 1 133 ? 126.601 177.425 111.151 1.00 64.64  ?  133 TYR B O     1 
ATOM 1029 C CB    . TYR A 1 133 ? 126.191 174.619 112.964 1.00 64.64  ?  133 TYR B CB    1 
ATOM 1030 C CG    . TYR A 1 133 ? 125.435 173.904 114.056 1.00 64.64  ?  133 TYR B CG    1 
ATOM 1031 C CD1   . TYR A 1 133 ? 126.067 173.533 115.233 1.00 64.64  ?  133 TYR B CD1   1 
ATOM 1032 C CD2   . TYR A 1 133 ? 124.089 173.606 113.914 1.00 64.64  ?  133 TYR B CD2   1 
ATOM 1033 C CE1   . TYR A 1 133 ? 125.381 172.882 116.236 1.00 64.64  ?  133 TYR B CE1   1 
ATOM 1034 C CE2   . TYR A 1 133 ? 123.394 172.953 114.913 1.00 64.64  ?  133 TYR B CE2   1 
ATOM 1035 C CZ    . TYR A 1 133 ? 124.046 172.594 116.071 1.00 64.64  ?  133 TYR B CZ    1 
ATOM 1036 O OH    . TYR A 1 133 ? 123.361 171.944 117.071 1.00 64.64  ?  133 TYR B OH    1 
ATOM 1037 N N     . SER A 1 134 ? 128.416 176.574 112.187 1.00 60.03  ?  134 SER B N     1 
ATOM 1038 C CA    . SER A 1 134 ? 129.372 177.173 111.260 1.00 60.03  ?  134 SER B CA    1 
ATOM 1039 C C     . SER A 1 134 ? 129.746 176.218 110.128 1.00 60.03  ?  134 SER B C     1 
ATOM 1040 O O     . SER A 1 134 ? 129.514 176.518 108.953 1.00 60.03  ?  134 SER B O     1 
ATOM 1041 C CB    . SER A 1 134 ? 130.623 177.621 112.023 1.00 60.03  ?  134 SER B CB    1 
ATOM 1042 O OG    . SER A 1 134 ? 130.278 178.454 113.115 1.00 60.03  ?  134 SER B OG    1 
ATOM 1043 N N     . CYS A 1 135 ? 130.323 175.066 110.465 1.00 49.64  ?  135 CYS B N     1 
ATOM 1044 C CA    . CYS A 1 135 ? 130.733 174.075 109.475 1.00 49.64  ?  135 CYS B CA    1 
ATOM 1045 C C     . CYS A 1 135 ? 129.672 172.983 109.424 1.00 49.64  ?  135 CYS B C     1 
ATOM 1046 O O     . CYS A 1 135 ? 129.467 172.260 110.404 1.00 49.64  ?  135 CYS B O     1 
ATOM 1047 C CB    . CYS A 1 135 ? 132.109 173.492 109.806 1.00 49.64  ?  135 CYS B CB    1 
ATOM 1048 S SG    . CYS A 1 135 ? 132.872 172.532 108.451 1.00 49.64  ?  135 CYS B SG    1 
ATOM 1049 N N     . VAL A 1 136 ? 128.994 172.873 108.286 1.00 40.58  ?  136 VAL B N     1 
ATOM 1050 C CA    . VAL A 1 136 ? 128.019 171.818 108.037 1.00 40.58  ?  136 VAL B CA    1 
ATOM 1051 C C     . VAL A 1 136 ? 128.463 171.066 106.791 1.00 40.58  ?  136 VAL B C     1 
ATOM 1052 O O     . VAL A 1 136 ? 128.641 171.669 105.725 1.00 40.58  ?  136 VAL B O     1 
ATOM 1053 C CB    . VAL A 1 136 ? 126.597 172.376 107.873 1.00 40.58  ?  136 VAL B CB    1 
ATOM 1054 C CG1   . VAL A 1 136 ? 126.000 172.687 109.229 1.00 40.58  ?  136 VAL B CG1   1 
ATOM 1055 C CG2   . VAL A 1 136 ? 126.612 173.628 107.017 1.00 40.58  ?  136 VAL B CG2   1 
ATOM 1056 N N     . VAL A 1 137 ? 128.652 169.757 106.925 1.00 32.91  ?  137 VAL B N     1 
ATOM 1057 C CA    . VAL A 1 137 ? 129.153 168.924 105.841 1.00 32.91  ?  137 VAL B CA    1 
ATOM 1058 C C     . VAL A 1 137 ? 128.255 167.705 105.690 1.00 32.91  ?  137 VAL B C     1 
ATOM 1059 O O     . VAL A 1 137 ? 127.893 167.058 106.678 1.00 32.91  ?  137 VAL B O     1 
ATOM 1060 C CB    . VAL A 1 137 ? 130.618 168.500 106.080 1.00 32.91  ?  137 VAL B CB    1 
ATOM 1061 C CG1   . VAL A 1 137 ? 131.528 169.707 106.027 1.00 32.91  ?  137 VAL B CG1   1 
ATOM 1062 C CG2   . VAL A 1 137 ? 130.766 167.808 107.420 1.00 32.91  ?  137 VAL B CG2   1 
ATOM 1063 N N     . LYS A 1 138 ? 127.878 167.407 104.451 1.00 34.20  ?  138 LYS B N     1 
ATOM 1064 C CA    . LYS A 1 138 ? 127.168 166.182 104.110 1.00 34.20  ?  138 LYS B CA    1 
ATOM 1065 C C     . LYS A 1 138 ? 128.112 165.318 103.291 1.00 34.20  ?  138 LYS B C     1 
ATOM 1066 O O     . LYS A 1 138 ? 128.603 165.756 102.248 1.00 34.20  ?  138 LYS B O     1 
ATOM 1067 C CB    . LYS A 1 138 ? 125.892 166.479 103.326 1.00 34.20  ?  138 LYS B CB    1 
ATOM 1068 C CG    . LYS A 1 138 ? 125.062 167.618 103.888 1.00 34.20  ?  138 LYS B CG    1 
ATOM 1069 C CD    . LYS A 1 138 ? 123.832 167.870 103.032 1.00 34.20  ?  138 LYS B CD    1 
ATOM 1070 C CE    . LYS A 1 138 ? 123.138 166.567 102.667 1.00 34.20  ?  138 LYS B CE    1 
ATOM 1071 N NZ    . LYS A 1 138 ? 122.426 166.664 101.364 1.00 34.20  1  138 LYS B NZ    1 
ATOM 1072 N N     . MET A 1 139 ? 128.361 164.099 103.755 1.00 31.79  ?  139 MET B N     1 
ATOM 1073 C CA    . MET A 1 139 ? 129.403 163.272 103.167 1.00 31.79  ?  139 MET B CA    1 
ATOM 1074 C C     . MET A 1 139 ? 129.083 161.812 103.457 1.00 31.79  ?  139 MET B C     1 
ATOM 1075 O O     . MET A 1 139 ? 128.376 161.512 104.426 1.00 31.79  ?  139 MET B O     1 
ATOM 1076 C CB    . MET A 1 139 ? 130.784 163.667 103.713 1.00 31.79  ?  139 MET B CB    1 
ATOM 1077 C CG    . MET A 1 139 ? 131.022 163.328 105.167 1.00 31.79  ?  139 MET B CG    1 
ATOM 1078 S SD    . MET A 1 139 ? 132.764 163.520 105.576 1.00 31.79  ?  139 MET B SD    1 
ATOM 1079 C CE    . MET A 1 139 ? 133.175 161.869 106.104 1.00 31.79  ?  139 MET B CE    1 
ATOM 1080 N N     . PRO A 1 140 ? 129.573 160.887 102.629 1.00 35.94  ?  140 PRO B N     1 
ATOM 1081 C CA    . PRO A 1 140 ? 129.175 159.480 102.770 1.00 35.94  ?  140 PRO B CA    1 
ATOM 1082 C C     . PRO A 1 140 ? 129.541 158.904 104.129 1.00 35.94  ?  140 PRO B C     1 
ATOM 1083 O O     . PRO A 1 140 ? 130.570 159.239 104.717 1.00 35.94  ?  140 PRO B O     1 
ATOM 1084 C CB    . PRO A 1 140 ? 129.947 158.780 101.646 1.00 35.94  ?  140 PRO B CB    1 
ATOM 1085 C CG    . PRO A 1 140 ? 130.238 159.850 100.662 1.00 35.94  ?  140 PRO B CG    1 
ATOM 1086 C CD    . PRO A 1 140 ? 130.429 161.101 101.451 1.00 35.94  ?  140 PRO B CD    1 
ATOM 1087 N N     . SER A 1 141 ? 128.671 158.021 104.624 1.00 32.53  ?  141 SER B N     1 
ATOM 1088 C CA    . SER A 1 141 ? 128.887 157.411 105.931 1.00 32.53  ?  141 SER B CA    1 
ATOM 1089 C C     . SER A 1 141 ? 130.107 156.501 105.930 1.00 32.53  ?  141 SER B C     1 
ATOM 1090 O O     . SER A 1 141 ? 130.877 156.483 106.900 1.00 32.53  ?  141 SER B O     1 
ATOM 1091 C CB    . SER A 1 141 ? 127.645 156.632 106.354 1.00 32.53  ?  141 SER B CB    1 
ATOM 1092 O OG    . SER A 1 141 ? 127.282 155.692 105.360 1.00 32.53  ?  141 SER B OG    1 
ATOM 1093 N N     . GLY A 1 142 ? 130.289 155.726 104.859 1.00 35.72  ?  142 GLY B N     1 
ATOM 1094 C CA    . GLY A 1 142 ? 131.432 154.831 104.793 1.00 35.72  ?  142 GLY B CA    1 
ATOM 1095 C C     . GLY A 1 142 ? 132.752 155.570 104.880 1.00 35.72  ?  142 GLY B C     1 
ATOM 1096 O O     . GLY A 1 142 ? 133.696 155.103 105.522 1.00 35.72  ?  142 GLY B O     1 
ATOM 1097 N N     . GLU A 1 143 ? 132.832 156.739 104.242 1.00 37.49  ?  143 GLU B N     1 
ATOM 1098 C CA    . GLU A 1 143 ? 134.047 157.539 104.322 1.00 37.49  ?  143 GLU B CA    1 
ATOM 1099 C C     . GLU A 1 143 ? 134.320 157.987 105.751 1.00 37.49  ?  143 GLU B C     1 
ATOM 1100 O O     . GLU A 1 143 ? 135.467 157.951 106.208 1.00 37.49  ?  143 GLU B O     1 
ATOM 1101 C CB    . GLU A 1 143 ? 133.944 158.744 103.390 1.00 37.49  ?  143 GLU B CB    1 
ATOM 1102 C CG    . GLU A 1 143 ? 135.193 158.980 102.568 1.00 37.49  ?  143 GLU B CG    1 
ATOM 1103 C CD    . GLU A 1 143 ? 135.463 157.859 101.586 1.00 37.49  ?  143 GLU B CD    1 
ATOM 1104 O OE1   . GLU A 1 143 ? 134.501 157.169 101.188 1.00 37.49  ?  143 GLU B OE1   1 
ATOM 1105 O OE2   . GLU A 1 143 ? 136.639 157.663 101.214 1.00 37.49  -1 143 GLU B OE2   1 
ATOM 1106 N N     . PHE A 1 144 ? 133.282 158.414 106.473 1.00 33.93  ?  144 PHE B N     1 
ATOM 1107 C CA    . PHE A 1 144 ? 133.476 158.819 107.862 1.00 33.93  ?  144 PHE B CA    1 
ATOM 1108 C C     . PHE A 1 144 ? 133.937 157.652 108.720 1.00 33.93  ?  144 PHE B C     1 
ATOM 1109 O O     . PHE A 1 144 ? 134.844 157.799 109.551 1.00 33.93  ?  144 PHE B O     1 
ATOM 1110 C CB    . PHE A 1 144 ? 132.187 159.410 108.425 1.00 33.93  ?  144 PHE B CB    1 
ATOM 1111 C CG    . PHE A 1 144 ? 132.396 160.241 109.651 1.00 33.93  ?  144 PHE B CG    1 
ATOM 1112 C CD1   . PHE A 1 144 ? 133.482 161.090 109.745 1.00 33.93  ?  144 PHE B CD1   1 
ATOM 1113 C CD2   . PHE A 1 144 ? 131.516 160.168 110.713 1.00 33.93  ?  144 PHE B CD2   1 
ATOM 1114 C CE1   . PHE A 1 144 ? 133.684 161.856 110.872 1.00 33.93  ?  144 PHE B CE1   1 
ATOM 1115 C CE2   . PHE A 1 144 ? 131.713 160.931 111.843 1.00 33.93  ?  144 PHE B CE2   1 
ATOM 1116 C CZ    . PHE A 1 144 ? 132.799 161.776 111.922 1.00 33.93  ?  144 PHE B CZ    1 
ATOM 1117 N N     . ALA A 1 145 ? 133.318 156.484 108.540 1.00 37.42  ?  145 ALA B N     1 
ATOM 1118 C CA    . ALA A 1 145 ? 133.728 155.317 109.312 1.00 37.42  ?  145 ALA B CA    1 
ATOM 1119 C C     . ALA A 1 145 ? 135.177 154.958 109.025 1.00 37.42  ?  145 ALA B C     1 
ATOM 1120 O O     . ALA A 1 145 ? 135.951 154.672 109.947 1.00 37.42  ?  145 ALA B O     1 
ATOM 1121 C CB    . ALA A 1 145 ? 132.811 154.135 109.007 1.00 37.42  ?  145 ALA B CB    1 
ATOM 1122 N N     . ARG A 1 146 ? 135.568 154.987 107.749 1.00 39.80  ?  146 ARG B N     1 
ATOM 1123 C CA    . ARG A 1 146 ? 136.942 154.666 107.388 1.00 39.80  ?  146 ARG B CA    1 
ATOM 1124 C C     . ARG A 1 146 ? 137.918 155.682 107.966 1.00 39.80  ?  146 ARG B C     1 
ATOM 1125 O O     . ARG A 1 146 ? 138.990 155.310 108.452 1.00 39.80  ?  146 ARG B O     1 
ATOM 1126 C CB    . ARG A 1 146 ? 137.076 154.590 105.869 1.00 39.80  ?  146 ARG B CB    1 
ATOM 1127 C CG    . ARG A 1 146 ? 138.499 154.401 105.377 1.00 39.80  ?  146 ARG B CG    1 
ATOM 1128 C CD    . ARG A 1 146 ? 138.580 154.354 103.847 1.00 39.80  ?  146 ARG B CD    1 
ATOM 1129 N NE    . ARG A 1 146 ? 137.506 153.625 103.171 1.00 39.80  ?  146 ARG B NE    1 
ATOM 1130 C CZ    . ARG A 1 146 ? 137.085 152.400 103.466 1.00 39.80  ?  146 ARG B CZ    1 
ATOM 1131 N NH1   . ARG A 1 146 ? 137.676 151.662 104.393 1.00 39.80  1  146 ARG B NH1   1 
ATOM 1132 N NH2   . ARG A 1 146 ? 136.056 151.891 102.796 1.00 39.80  ?  146 ARG B NH2   1 
ATOM 1133 N N     . ILE A 1 147 ? 137.563 156.968 107.929 1.00 34.97  ?  147 ILE B N     1 
ATOM 1134 C CA    . ILE A 1 147 ? 138.450 158.001 108.457 1.00 34.97  ?  147 ILE B CA    1 
ATOM 1135 C C     . ILE A 1 147 ? 138.656 157.810 109.953 1.00 34.97  ?  147 ILE B C     1 
ATOM 1136 O O     . ILE A 1 147 ? 139.787 157.852 110.454 1.00 34.97  ?  147 ILE B O     1 
ATOM 1137 C CB    . ILE A 1 147 ? 137.894 159.400 108.143 1.00 34.97  ?  147 ILE B CB    1 
ATOM 1138 C CG1   . ILE A 1 147 ? 138.045 159.714 106.656 1.00 34.97  ?  147 ILE B CG1   1 
ATOM 1139 C CG2   . ILE A 1 147 ? 138.590 160.451 108.984 1.00 34.97  ?  147 ILE B CG2   1 
ATOM 1140 C CD1   . ILE A 1 147 ? 139.368 159.293 106.083 1.00 34.97  ?  147 ILE B CD1   1 
ATOM 1141 N N     . CYS A 1 148 ? 137.564 157.598 110.691 1.00 38.20  ?  148 CYS B N     1 
ATOM 1142 C CA    . CYS A 1 148 ? 137.686 157.413 112.133 1.00 38.20  ?  148 CYS B CA    1 
ATOM 1143 C C     . CYS A 1 148 ? 138.486 156.159 112.463 1.00 38.20  ?  148 CYS B C     1 
ATOM 1144 O O     . CYS A 1 148 ? 139.357 156.183 113.344 1.00 38.20  ?  148 CYS B O     1 
ATOM 1145 C CB    . CYS A 1 148 ? 136.302 157.357 112.774 1.00 38.20  ?  148 CYS B CB    1 
ATOM 1146 S SG    . CYS A 1 148 ? 135.464 158.954 112.842 1.00 38.20  ?  148 CYS B SG    1 
ATOM 1147 N N     . ARG A 1 149 ? 138.220 155.057 111.758 1.00 42.95  ?  149 ARG B N     1 
ATOM 1148 C CA    . ARG A 1 149 ? 138.950 153.822 112.024 1.00 42.95  ?  149 ARG B CA    1 
ATOM 1149 C C     . ARG A 1 149 ? 140.434 153.981 111.720 1.00 42.95  ?  149 ARG B C     1 
ATOM 1150 O O     . ARG A 1 149 ? 141.284 153.498 112.477 1.00 42.95  ?  149 ARG B O     1 
ATOM 1151 C CB    . ARG A 1 149 ? 138.351 152.676 111.211 1.00 42.95  ?  149 ARG B CB    1 
ATOM 1152 C CG    . ARG A 1 149 ? 139.007 151.330 111.452 1.00 42.95  ?  149 ARG B CG    1 
ATOM 1153 C CD    . ARG A 1 149 ? 138.505 150.291 110.463 1.00 42.95  ?  149 ARG B CD    1 
ATOM 1154 N NE    . ARG A 1 149 ? 138.878 150.617 109.092 1.00 42.95  ?  149 ARG B NE    1 
ATOM 1155 C CZ    . ARG A 1 149 ? 139.969 150.171 108.485 1.00 42.95  ?  149 ARG B CZ    1 
ATOM 1156 N NH1   . ARG A 1 149 ? 140.824 149.370 109.100 1.00 42.95  1  149 ARG B NH1   1 
ATOM 1157 N NH2   . ARG A 1 149 ? 140.210 150.538 107.230 1.00 42.95  ?  149 ARG B NH2   1 
ATOM 1158 N N     . ASP A 1 150 ? 140.767 154.655 110.617 1.00 41.85  ?  150 ASP B N     1 
ATOM 1159 C CA    . ASP A 1 150 ? 142.167 154.859 110.269 1.00 41.85  ?  150 ASP B CA    1 
ATOM 1160 C C     . ASP A 1 150 ? 142.870 155.739 111.291 1.00 41.85  ?  150 ASP B C     1 
ATOM 1161 O O     . ASP A 1 150 ? 144.003 155.450 111.691 1.00 41.85  ?  150 ASP B O     1 
ATOM 1162 C CB    . ASP A 1 150 ? 142.277 155.471 108.874 1.00 41.85  ?  150 ASP B CB    1 
ATOM 1163 C CG    . ASP A 1 150 ? 141.975 154.475 107.777 1.00 41.85  ?  150 ASP B CG    1 
ATOM 1164 O OD1   . ASP A 1 150 ? 141.788 153.281 108.093 1.00 41.85  ?  150 ASP B OD1   1 
ATOM 1165 O OD2   . ASP A 1 150 ? 141.927 154.884 106.598 1.00 41.85  -1 150 ASP B OD2   1 
ATOM 1166 N N     . LEU A 1 151 ? 142.219 156.818 111.729 1.00 32.14  ?  151 LEU B N     1 
ATOM 1167 C CA    . LEU A 1 151 ? 142.862 157.712 112.682 1.00 32.14  ?  151 LEU B CA    1 
ATOM 1168 C C     . LEU A 1 151 ? 142.941 157.114 114.078 1.00 32.14  ?  151 LEU B C     1 
ATOM 1169 O O     . LEU A 1 151 ? 143.769 157.561 114.879 1.00 32.14  ?  151 LEU B O     1 
ATOM 1170 C CB    . LEU A 1 151 ? 142.132 159.052 112.731 1.00 32.14  ?  151 LEU B CB    1 
ATOM 1171 C CG    . LEU A 1 151 ? 142.474 160.028 111.606 1.00 32.14  ?  151 LEU B CG    1 
ATOM 1172 C CD1   . LEU A 1 151 ? 142.187 161.454 112.035 1.00 32.14  ?  151 LEU B CD1   1 
ATOM 1173 C CD2   . LEU A 1 151 ? 143.922 159.876 111.181 1.00 32.14  ?  151 LEU B CD2   1 
ATOM 1174 N N     . SER A 1 152 ? 142.105 156.122 114.392 1.00 39.26  ?  152 SER B N     1 
ATOM 1175 C CA    . SER A 1 152 ? 142.186 155.496 115.708 1.00 39.26  ?  152 SER B CA    1 
ATOM 1176 C C     . SER A 1 152 ? 143.526 154.806 115.927 1.00 39.26  ?  152 SER B C     1 
ATOM 1177 O O     . SER A 1 152 ? 143.974 154.673 117.071 1.00 39.26  ?  152 SER B O     1 
ATOM 1178 C CB    . SER A 1 152 ? 141.042 154.500 115.888 1.00 39.26  ?  152 SER B CB    1 
ATOM 1179 O OG    . SER A 1 152 ? 139.824 155.171 116.151 1.00 39.26  ?  152 SER B OG    1 
ATOM 1180 N N     . HIS A 1 153 ? 144.179 154.362 114.853 1.00 40.83  ?  153 HIS B N     1 
ATOM 1181 C CA    . HIS A 1 153 ? 145.449 153.660 114.993 1.00 40.83  ?  153 HIS B CA    1 
ATOM 1182 C C     . HIS A 1 153 ? 146.606 154.604 115.296 1.00 40.83  ?  153 HIS B C     1 
ATOM 1183 O O     . HIS A 1 153 ? 147.569 154.200 115.956 1.00 40.83  ?  153 HIS B O     1 
ATOM 1184 C CB    . HIS A 1 153 ? 145.750 152.858 113.727 1.00 40.83  ?  153 HIS B CB    1 
ATOM 1185 C CG    . HIS A 1 153 ? 144.713 151.827 113.407 1.00 40.83  ?  153 HIS B CG    1 
ATOM 1186 N ND1   . HIS A 1 153 ? 144.208 151.647 112.137 1.00 40.83  ?  153 HIS B ND1   1 
ATOM 1187 C CD2   . HIS A 1 153 ? 144.082 150.925 114.194 1.00 40.83  ?  153 HIS B CD2   1 
ATOM 1188 C CE1   . HIS A 1 153 ? 143.311 150.677 112.156 1.00 40.83  ?  153 HIS B CE1   1 
ATOM 1189 N NE2   . HIS A 1 153 ? 143.217 150.221 113.392 1.00 40.83  ?  153 HIS B NE2   1 
ATOM 1190 N N     . ILE A 1 154 ? 146.536 155.850 114.833 1.00 35.41  ?  154 ILE B N     1 
ATOM 1191 C CA    . ILE A 1 154 ? 147.636 156.791 115.007 1.00 35.41  ?  154 ILE B CA    1 
ATOM 1192 C C     . ILE A 1 154 ? 147.482 157.532 116.328 1.00 35.41  ?  154 ILE B C     1 
ATOM 1193 O O     . ILE A 1 154 ? 148.340 157.433 117.211 1.00 35.41  ?  154 ILE B O     1 
ATOM 1194 C CB    . ILE A 1 154 ? 147.715 157.780 113.831 1.00 35.41  ?  154 ILE B CB    1 
ATOM 1195 C CG1   . ILE A 1 154 ? 148.207 157.066 112.575 1.00 35.41  ?  154 ILE B CG1   1 
ATOM 1196 C CG2   . ILE A 1 154 ? 148.640 158.933 114.164 1.00 35.41  ?  154 ILE B CG2   1 
ATOM 1197 C CD1   . ILE A 1 154 ? 149.578 156.464 112.728 1.00 35.41  ?  154 ILE B CD1   1 
ATOM 1198 N N     . GLY A 1 155 ? 146.389 158.275 116.475 1.00 36.90  ?  155 GLY B N     1 
ATOM 1199 C CA    . GLY A 1 155 ? 146.193 159.082 117.661 1.00 36.90  ?  155 GLY B CA    1 
ATOM 1200 C C     . GLY A 1 155 ? 144.869 158.844 118.352 1.00 36.90  ?  155 GLY B C     1 
ATOM 1201 O O     . GLY A 1 155 ? 144.211 157.827 118.113 1.00 36.90  ?  155 GLY B O     1 
ATOM 1202 N N     . ASP A 1 156 ? 144.468 159.777 119.221 1.00 39.32  ?  156 ASP B N     1 
ATOM 1203 C CA    . ASP A 1 156 ? 143.205 159.641 119.936 1.00 39.32  ?  156 ASP B CA    1 
ATOM 1204 C C     . ASP A 1 156 ? 142.451 160.962 120.046 1.00 39.32  ?  156 ASP B C     1 
ATOM 1205 O O     . ASP A 1 156 ? 141.570 161.089 120.904 1.00 39.32  ?  156 ASP B O     1 
ATOM 1206 C CB    . ASP A 1 156 ? 143.435 159.067 121.336 1.00 39.32  ?  156 ASP B CB    1 
ATOM 1207 C CG    . ASP A 1 156 ? 143.636 157.566 121.323 1.00 39.32  ?  156 ASP B CG    1 
ATOM 1208 O OD1   . ASP A 1 156 ? 144.713 157.112 120.886 1.00 39.32  ?  156 ASP B OD1   1 
ATOM 1209 O OD2   . ASP A 1 156 ? 142.714 156.838 121.749 1.00 39.32  -1 156 ASP B OD2   1 
ATOM 1210 N N     . ALA A 1 157 ? 142.768 161.949 119.208 1.00 33.88  ?  157 ALA B N     1 
ATOM 1211 C CA    . ALA A 1 157 ? 142.084 163.239 119.263 1.00 33.88  ?  157 ALA B CA    1 
ATOM 1212 C C     . ALA A 1 157 ? 142.206 163.900 117.893 1.00 33.88  ?  157 ALA B C     1 
ATOM 1213 O O     . ALA A 1 157 ? 143.264 164.437 117.556 1.00 33.88  ?  157 ALA B O     1 
ATOM 1214 C CB    . ALA A 1 157 ? 142.665 164.119 120.360 1.00 33.88  ?  157 ALA B CB    1 
ATOM 1215 N N     . VAL A 1 158 ? 141.124 163.866 117.119 1.00 29.07  ?  158 VAL B N     1 
ATOM 1216 C CA    . VAL A 1 158 ? 141.132 164.497 115.807 1.00 29.07  ?  158 VAL B CA    1 
ATOM 1217 C C     . VAL A 1 158 ? 141.032 166.011 115.961 1.00 29.07  ?  158 VAL B C     1 
ATOM 1218 O O     . VAL A 1 158 ? 140.627 166.536 117.000 1.00 29.07  ?  158 VAL B O     1 
ATOM 1219 C CB    . VAL A 1 158 ? 140.001 163.953 114.919 1.00 29.07  ?  158 VAL B CB    1 
ATOM 1220 C CG1   . VAL A 1 158 ? 139.943 162.442 115.003 1.00 29.07  ?  158 VAL B CG1   1 
ATOM 1221 C CG2   . VAL A 1 158 ? 138.673 164.565 115.316 1.00 29.07  ?  158 VAL B CG2   1 
ATOM 1222 N N     . VAL A 1 159 ? 141.424 166.721 114.907 1.00 26.07  ?  159 VAL B N     1 
ATOM 1223 C CA    . VAL A 1 159 ? 141.340 168.181 114.856 1.00 26.07  ?  159 VAL B CA    1 
ATOM 1224 C C     . VAL A 1 159 ? 140.648 168.527 113.540 1.00 26.07  ?  159 VAL B C     1 
ATOM 1225 O O     . VAL A 1 159 ? 141.294 168.662 112.497 1.00 26.07  ?  159 VAL B O     1 
ATOM 1226 C CB    . VAL A 1 159 ? 142.710 168.857 114.957 1.00 26.07  ?  159 VAL B CB    1 
ATOM 1227 C CG1   . VAL A 1 159 ? 142.562 170.367 114.900 1.00 26.07  ?  159 VAL B CG1   1 
ATOM 1228 C CG2   . VAL A 1 159 ? 143.417 168.440 116.235 1.00 26.07  ?  159 VAL B CG2   1 
ATOM 1229 N N     . ILE A 1 160 ? 139.329 168.676 113.580 1.00 29.69  ?  160 ILE B N     1 
ATOM 1230 C CA    . ILE A 1 160 ? 138.562 168.988 112.379 1.00 29.69  ?  160 ILE B CA    1 
ATOM 1231 C C     . ILE A 1 160 ? 138.668 170.482 112.111 1.00 29.69  ?  160 ILE B C     1 
ATOM 1232 O O     . ILE A 1 160 ? 138.289 171.304 112.951 1.00 29.69  ?  160 ILE B O     1 
ATOM 1233 C CB    . ILE A 1 160 ? 137.101 168.548 112.524 1.00 29.69  ?  160 ILE B CB    1 
ATOM 1234 C CG1   . ILE A 1 160 ? 137.036 167.041 112.756 1.00 29.69  ?  160 ILE B CG1   1 
ATOM 1235 C CG2   . ILE A 1 160 ? 136.314 168.927 111.287 1.00 29.69  ?  160 ILE B CG2   1 
ATOM 1236 C CD1   . ILE A 1 160 ? 135.939 166.612 113.688 1.00 29.69  ?  160 ILE B CD1   1 
ATOM 1237 N N     . SER A 1 161 ? 139.194 170.834 110.943 1.00 38.28  ?  161 SER B N     1 
ATOM 1238 C CA    . SER A 1 161 ? 139.583 172.204 110.627 1.00 38.28  ?  161 SER B CA    1 
ATOM 1239 C C     . SER A 1 161 ? 139.138 172.580 109.218 1.00 38.28  ?  161 SER B C     1 
ATOM 1240 O O     . SER A 1 161 ? 139.956 172.964 108.382 1.00 38.28  ?  161 SER B O     1 
ATOM 1241 C CB    . SER A 1 161 ? 141.088 172.393 110.797 1.00 38.28  ?  161 SER B CB    1 
ATOM 1242 O OG    . SER A 1 161 ? 141.809 171.422 110.064 1.00 38.28  ?  161 SER B OG    1 
ATOM 1243 N N     . CYS A 1 162 ? 137.838 172.427 108.933 1.00 48.58  ?  162 CYS B N     1 
ATOM 1244 C CA    . CYS A 1 162 ? 137.279 172.586 107.591 1.00 48.58  ?  162 CYS B CA    1 
ATOM 1245 C C     . CYS A 1 162 ? 137.972 173.708 106.831 1.00 48.58  ?  162 CYS B C     1 
ATOM 1246 O O     . CYS A 1 162 ? 137.999 174.857 107.283 1.00 48.58  ?  162 CYS B O     1 
ATOM 1247 C CB    . CYS A 1 162 ? 135.776 172.889 107.669 1.00 48.58  ?  162 CYS B CB    1 
ATOM 1248 S SG    . CYS A 1 162 ? 134.796 172.159 109.012 1.00 48.58  ?  162 CYS B SG    1 
ATOM 1249 N N     . ALA A 1 163 ? 138.537 173.374 105.678 1.00 52.01  ?  163 ALA B N     1 
ATOM 1250 C CA    . ALA A 1 163 ? 139.421 174.264 104.942 1.00 52.01  ?  163 ALA B CA    1 
ATOM 1251 C C     . ALA A 1 163 ? 138.765 174.712 103.641 1.00 52.01  ?  163 ALA B C     1 
ATOM 1252 O O     . ALA A 1 163 ? 137.590 174.442 103.378 1.00 52.01  ?  163 ALA B O     1 
ATOM 1253 C CB    . ALA A 1 163 ? 140.765 173.584 104.673 1.00 52.01  ?  163 ALA B CB    1 
ATOM 1254 N N     . LYS A 1 164 ? 139.551 175.419 102.825 1.00 65.89  ?  164 LYS B N     1 
ATOM 1255 C CA    . LYS A 1 164 ? 139.033 175.966 101.575 1.00 65.89  ?  164 LYS B CA    1 
ATOM 1256 C C     . LYS A 1 164 ? 138.602 174.854 100.624 1.00 65.89  ?  164 LYS B C     1 
ATOM 1257 O O     . LYS A 1 164 ? 137.517 174.919 100.035 1.00 65.89  ?  164 LYS B O     1 
ATOM 1258 C CB    . LYS A 1 164 ? 140.096 176.865 100.933 1.00 65.89  ?  164 LYS B CB    1 
ATOM 1259 C CG    . LYS A 1 164 ? 140.209 176.821 99.407  1.00 65.89  ?  164 LYS B CG    1 
ATOM 1260 C CD    . LYS A 1 164 ? 138.983 177.405 98.709  1.00 65.89  ?  164 LYS B CD    1 
ATOM 1261 C CE    . LYS A 1 164 ? 138.738 176.731 97.367  1.00 65.89  ?  164 LYS B CE    1 
ATOM 1262 N NZ    . LYS A 1 164 ? 138.286 175.321 97.520  1.00 65.89  1  164 LYS B NZ    1 
ATOM 1263 N N     . ASP A 1 165 ? 139.430 173.821 100.469 1.00 63.43  ?  165 ASP B N     1 
ATOM 1264 C CA    . ASP A 1 165 ? 139.135 172.754 99.522  1.00 63.43  ?  165 ASP B CA    1 
ATOM 1265 C C     . ASP A 1 165 ? 138.348 171.602 100.128 1.00 63.43  ?  165 ASP B C     1 
ATOM 1266 O O     . ASP A 1 165 ? 137.781 170.801 99.377  1.00 63.43  ?  165 ASP B O     1 
ATOM 1267 C CB    . ASP A 1 165 ? 140.431 172.204 98.917  1.00 63.43  ?  165 ASP B CB    1 
ATOM 1268 C CG    . ASP A 1 165 ? 140.239 171.692 97.504  1.00 63.43  ?  165 ASP B CG    1 
ATOM 1269 O OD1   . ASP A 1 165 ? 139.259 172.107 96.850  1.00 63.43  ?  165 ASP B OD1   1 
ATOM 1270 O OD2   . ASP A 1 165 ? 141.065 170.874 97.049  1.00 63.43  -1 165 ASP B OD2   1 
ATOM 1271 N N     . GLY A 1 166 ? 138.294 171.499 101.449 1.00 49.72  ?  166 GLY B N     1 
ATOM 1272 C CA    . GLY A 1 166 ? 137.560 170.416 102.074 1.00 49.72  ?  166 GLY B CA    1 
ATOM 1273 C C     . GLY A 1 166 ? 138.002 170.234 103.514 1.00 49.72  ?  166 GLY B C     1 
ATOM 1274 O O     . GLY A 1 166 ? 138.722 171.061 104.068 1.00 49.72  ?  166 GLY B O     1 
ATOM 1275 N N     . VAL A 1 167 ? 137.547 169.125 104.096 1.00 37.30  ?  167 VAL B N     1 
ATOM 1276 C CA    . VAL A 1 167 ? 137.846 168.839 105.490 1.00 37.30  ?  167 VAL B CA    1 
ATOM 1277 C C     . VAL A 1 167 ? 139.314 168.454 105.653 1.00 37.30  ?  167 VAL B C     1 
ATOM 1278 O O     . VAL A 1 167 ? 140.018 168.121 104.694 1.00 37.30  ?  167 VAL B O     1 
ATOM 1279 C CB    . VAL A 1 167 ? 136.916 167.737 106.014 1.00 37.30  ?  167 VAL B CB    1 
ATOM 1280 C CG1   . VAL A 1 167 ? 135.498 167.988 105.539 1.00 37.30  ?  167 VAL B CG1   1 
ATOM 1281 C CG2   . VAL A 1 167 ? 137.388 166.411 105.505 1.00 37.30  ?  167 VAL B CG2   1 
ATOM 1282 N N     . LYS A 1 168 ? 139.783 168.521 106.899 1.00 31.62  ?  168 LYS B N     1 
ATOM 1283 C CA    . LYS A 1 168 ? 141.194 168.360 107.232 1.00 31.62  ?  168 LYS B CA    1 
ATOM 1284 C C     . LYS A 1 168 ? 141.360 167.475 108.472 1.00 31.62  ?  168 LYS B C     1 
ATOM 1285 O O     . LYS A 1 168 ? 141.952 167.867 109.472 1.00 31.62  ?  168 LYS B O     1 
ATOM 1286 C CB    . LYS A 1 168 ? 141.868 169.717 107.418 1.00 31.62  ?  168 LYS B CB    1 
ATOM 1287 C CG    . LYS A 1 168 ? 143.388 169.661 107.358 1.00 31.62  ?  168 LYS B CG    1 
ATOM 1288 C CD    . LYS A 1 168 ? 143.992 171.045 107.208 1.00 31.62  ?  168 LYS B CD    1 
ATOM 1289 C CE    . LYS A 1 168 ? 143.706 171.621 105.832 1.00 31.62  ?  168 LYS B CE    1 
ATOM 1290 N NZ    . LYS A 1 168 ? 143.859 170.600 104.760 1.00 31.62  1  168 LYS B NZ    1 
ATOM 1291 N N     . PHE A 1 169 ? 140.822 166.254 108.425 1.00 29.58  ?  169 PHE B N     1 
ATOM 1292 C CA    . PHE A 1 169 ? 140.744 165.402 109.614 1.00 29.58  ?  169 PHE B CA    1 
ATOM 1293 C C     . PHE A 1 169 ? 142.155 165.015 110.045 1.00 29.58  ?  169 PHE B C     1 
ATOM 1294 O O     . PHE A 1 169 ? 142.627 163.897 109.832 1.00 29.58  ?  169 PHE B O     1 
ATOM 1295 C CB    . PHE A 1 169 ? 139.933 164.142 109.333 1.00 29.58  ?  169 PHE B CB    1 
ATOM 1296 C CG    . PHE A 1 169 ? 138.456 164.322 109.438 1.00 29.58  ?  169 PHE B CG    1 
ATOM 1297 C CD1   . PHE A 1 169 ? 137.810 164.148 110.646 1.00 29.58  ?  169 PHE B CD1   1 
ATOM 1298 C CD2   . PHE A 1 169 ? 137.706 164.626 108.324 1.00 29.58  ?  169 PHE B CD2   1 
ATOM 1299 C CE1   . PHE A 1 169 ? 136.445 164.299 110.741 1.00 29.58  ?  169 PHE B CE1   1 
ATOM 1300 C CE2   . PHE A 1 169 ? 136.342 164.780 108.412 1.00 29.58  ?  169 PHE B CE2   1 
ATOM 1301 C CZ    . PHE A 1 169 ? 135.710 164.617 109.622 1.00 29.58  ?  169 PHE B CZ    1 
ATOM 1302 N N     . SER A 1 170 ? 142.833 165.963 110.683 1.00 25.28  ?  170 SER B N     1 
ATOM 1303 C CA    . SER A 1 170 ? 144.182 165.731 111.167 1.00 25.28  ?  170 SER B CA    1 
ATOM 1304 C C     . SER A 1 170 ? 144.154 165.043 112.529 1.00 25.28  ?  170 SER B C     1 
ATOM 1305 O O     . SER A 1 170 ? 143.108 164.900 113.166 1.00 25.28  ?  170 SER B O     1 
ATOM 1306 C CB    . SER A 1 170 ? 144.954 167.044 111.254 1.00 25.28  ?  170 SER B CB    1 
ATOM 1307 O OG    . SER A 1 170 ? 145.982 166.959 112.224 1.00 25.28  ?  170 SER B OG    1 
ATOM 1308 N N     . ALA A 1 171 ? 145.330 164.613 112.972 1.00 23.61  ?  171 ALA B N     1 
ATOM 1309 C CA    . ALA A 1 171 ? 145.499 163.968 114.268 1.00 23.61  ?  171 ALA B CA    1 
ATOM 1310 C C     . ALA A 1 171 ? 146.974 164.042 114.642 1.00 23.61  ?  171 ALA B C     1 
ATOM 1311 O O     . ALA A 1 171 ? 147.778 164.661 113.937 1.00 23.61  ?  171 ALA B O     1 
ATOM 1312 C CB    . ALA A 1 171 ? 144.990 162.523 114.237 1.00 23.61  ?  171 ALA B CB    1 
ATOM 1313 N N     . SER A 1 172 ? 147.330 163.414 115.758 1.00 33.37  ?  172 SER B N     1 
ATOM 1314 C CA    . SER A 1 172 ? 148.720 163.345 116.185 1.00 33.37  ?  172 SER B CA    1 
ATOM 1315 C C     . SER A 1 172 ? 148.867 162.203 117.176 1.00 33.37  ?  172 SER B C     1 
ATOM 1316 O O     . SER A 1 172 ? 147.890 161.748 117.775 1.00 33.37  ?  172 SER B O     1 
ATOM 1317 C CB    . SER A 1 172 ? 149.188 164.664 116.808 1.00 33.37  ?  172 SER B CB    1 
ATOM 1318 O OG    . SER A 1 172 ? 150.474 164.520 117.385 1.00 33.37  ?  172 SER B OG    1 
ATOM 1319 N N     . GLY A 1 173 ? 150.103 161.753 117.350 1.00 39.67  ?  173 GLY B N     1 
ATOM 1320 C CA    . GLY A 1 173 ? 150.360 160.648 118.253 1.00 39.67  ?  173 GLY B CA    1 
ATOM 1321 C C     . GLY A 1 173 ? 151.839 160.342 118.310 1.00 39.67  ?  173 GLY B C     1 
ATOM 1322 O O     . GLY A 1 173 ? 152.662 160.998 117.664 1.00 39.67  ?  173 GLY B O     1 
ATOM 1323 N N     . GLU A 1 174 ? 152.166 159.324 119.110 1.00 48.01  ?  174 GLU B N     1 
ATOM 1324 C CA    . GLU A 1 174 ? 153.561 158.929 119.275 1.00 48.01  ?  174 GLU B CA    1 
ATOM 1325 C C     . GLU A 1 174 ? 154.147 158.389 117.976 1.00 48.01  ?  174 GLU B C     1 
ATOM 1326 O O     . GLU A 1 174 ? 155.308 158.665 117.651 1.00 48.01  ?  174 GLU B O     1 
ATOM 1327 C CB    . GLU A 1 174 ? 153.682 157.895 120.395 1.00 48.01  ?  174 GLU B CB    1 
ATOM 1328 C CG    . GLU A 1 174 ? 152.513 156.929 120.477 1.00 48.01  ?  174 GLU B CG    1 
ATOM 1329 C CD    . GLU A 1 174 ? 152.687 155.728 119.572 1.00 48.01  ?  174 GLU B CD    1 
ATOM 1330 O OE1   . GLU A 1 174 ? 153.821 155.499 119.101 1.00 48.01  ?  174 GLU B OE1   1 
ATOM 1331 O OE2   . GLU A 1 174 ? 151.692 155.015 119.329 1.00 48.01  -1 174 GLU B OE2   1 
ATOM 1332 N N     . LEU A 1 175 ? 153.366 157.609 117.225 1.00 44.21  ?  175 LEU B N     1 
ATOM 1333 C CA    . LEU A 1 175 ? 153.853 157.080 115.955 1.00 44.21  ?  175 LEU B CA    1 
ATOM 1334 C C     . LEU A 1 175 ? 154.140 158.199 114.964 1.00 44.21  ?  175 LEU B C     1 
ATOM 1335 O O     . LEU A 1 175 ? 155.149 158.163 114.252 1.00 44.21  ?  175 LEU B O     1 
ATOM 1336 C CB    . LEU A 1 175 ? 152.838 156.096 115.373 1.00 44.21  ?  175 LEU B CB    1 
ATOM 1337 C CG    . LEU A 1 175 ? 152.807 154.696 115.987 1.00 44.21  ?  175 LEU B CG    1 
ATOM 1338 C CD1   . LEU A 1 175 ? 151.970 153.754 115.138 1.00 44.21  ?  175 LEU B CD1   1 
ATOM 1339 C CD2   . LEU A 1 175 ? 154.217 154.157 116.152 1.00 44.21  ?  175 LEU B CD2   1 
ATOM 1340 N N     . GLY A 1 176 ? 153.270 159.202 114.909 1.00 39.14  ?  176 GLY B N     1 
ATOM 1341 C CA    . GLY A 1 176 ? 153.431 160.302 113.982 1.00 39.14  ?  176 GLY B CA    1 
ATOM 1342 C C     . GLY A 1 176 ? 152.222 161.211 113.967 1.00 39.14  ?  176 GLY B C     1 
ATOM 1343 O O     . GLY A 1 176 ? 151.685 161.553 115.025 1.00 39.14  ?  176 GLY B O     1 
ATOM 1344 N N     . ASN A 1 177 ? 151.782 161.608 112.777 1.00 33.52  ?  177 ASN B N     1 
ATOM 1345 C CA    . ASN A 1 177 ? 150.611 162.463 112.645 1.00 33.52  ?  177 ASN B CA    1 
ATOM 1346 C C     . ASN A 1 177 ? 150.045 162.344 111.239 1.00 33.52  ?  177 ASN B C     1 
ATOM 1347 O O     . ASN A 1 177 ? 150.752 162.586 110.257 1.00 33.52  ?  177 ASN B O     1 
ATOM 1348 C CB    . ASN A 1 177 ? 150.954 163.919 112.983 1.00 33.52  ?  177 ASN B CB    1 
ATOM 1349 C CG    . ASN A 1 177 ? 152.269 164.369 112.378 1.00 33.52  ?  177 ASN B CG    1 
ATOM 1350 O OD1   . ASN A 1 177 ? 152.800 163.737 111.469 1.00 33.52  ?  177 ASN B OD1   1 
ATOM 1351 N ND2   . ASN A 1 177 ? 152.804 165.470 112.889 1.00 33.52  ?  177 ASN B ND2   1 
ATOM 1352 N N     . GLY A 1 178 ? 148.773 161.968 111.148 1.00 25.70  ?  178 GLY B N     1 
ATOM 1353 C CA    . GLY A 1 178 ? 148.097 161.790 109.875 1.00 25.70  ?  178 GLY B CA    1 
ATOM 1354 C C     . GLY A 1 178 ? 147.206 162.980 109.571 1.00 25.70  ?  178 GLY B C     1 
ATOM 1355 O O     . GLY A 1 178 ? 146.420 163.412 110.416 1.00 25.70  ?  178 GLY B O     1 
ATOM 1356 N N     . ASN A 1 179 ? 147.344 163.506 108.357 1.00 29.30  ?  179 ASN B N     1 
ATOM 1357 C CA    . ASN A 1 179 ? 146.573 164.659 107.898 1.00 29.30  ?  179 ASN B CA    1 
ATOM 1358 C C     . ASN A 1 179 ? 145.749 164.228 106.690 1.00 29.30  ?  179 ASN B C     1 
ATOM 1359 O O     . ASN A 1 179 ? 146.171 164.397 105.544 1.00 29.30  ?  179 ASN B O     1 
ATOM 1360 C CB    . ASN A 1 179 ? 147.486 165.831 107.555 1.00 29.30  ?  179 ASN B CB    1 
ATOM 1361 C CG    . ASN A 1 179 ? 148.576 166.041 108.583 1.00 29.30  ?  179 ASN B CG    1 
ATOM 1362 O OD1   . ASN A 1 179 ? 148.440 165.649 109.740 1.00 29.30  ?  179 ASN B OD1   1 
ATOM 1363 N ND2   . ASN A 1 179 ? 149.670 166.666 108.164 1.00 29.30  ?  179 ASN B ND2   1 
ATOM 1364 N N     . ILE A 1 180 ? 144.570 163.682 106.949 1.00 21.85  ?  180 ILE B N     1 
ATOM 1365 C CA    . ILE A 1 180 ? 143.669 163.273 105.880 1.00 21.85  ?  180 ILE B CA    1 
ATOM 1366 C C     . ILE A 1 180 ? 142.912 164.490 105.367 1.00 21.85  ?  180 ILE B C     1 
ATOM 1367 O O     . ILE A 1 180 ? 142.678 165.456 106.099 1.00 21.85  ?  180 ILE B O     1 
ATOM 1368 C CB    . ILE A 1 180 ? 142.711 162.176 106.376 1.00 21.85  ?  180 ILE B CB    1 
ATOM 1369 C CG1   . ILE A 1 180 ? 143.463 161.196 107.276 1.00 21.85  ?  180 ILE B CG1   1 
ATOM 1370 C CG2   . ILE A 1 180 ? 142.086 161.452 105.205 1.00 21.85  ?  180 ILE B CG2   1 
ATOM 1371 C CD1   . ILE A 1 180 ? 142.738 159.896 107.507 1.00 21.85  ?  180 ILE B CD1   1 
ATOM 1372 N N     . LYS A 1 181 ? 142.526 164.450 104.094 1.00 39.03  ?  181 LYS B N     1 
ATOM 1373 C CA    . LYS A 1 181 ? 141.867 165.594 103.471 1.00 39.03  ?  181 LYS B CA    1 
ATOM 1374 C C     . LYS A 1 181 ? 141.055 165.112 102.278 1.00 39.03  ?  181 LYS B C     1 
ATOM 1375 O O     . LYS A 1 181 ? 141.624 164.616 101.302 1.00 39.03  ?  181 LYS B O     1 
ATOM 1376 C CB    . LYS A 1 181 ? 142.890 166.641 103.044 1.00 39.03  ?  181 LYS B CB    1 
ATOM 1377 C CG    . LYS A 1 181 ? 142.354 167.659 102.055 1.00 39.03  ?  181 LYS B CG    1 
ATOM 1378 C CD    . LYS A 1 181 ? 143.434 168.098 101.084 1.00 39.03  ?  181 LYS B CD    1 
ATOM 1379 C CE    . LYS A 1 181 ? 142.855 168.936 99.960  1.00 39.03  ?  181 LYS B CE    1 
ATOM 1380 N NZ    . LYS A 1 181 ? 142.896 170.388 100.282 1.00 39.03  1  181 LYS B NZ    1 
ATOM 1381 N N     . LEU A 1 182 ? 139.737 165.258 102.356 1.00 42.92  ?  182 LEU B N     1 
ATOM 1382 C CA    . LEU A 1 182 ? 138.870 165.024 101.212 1.00 42.92  ?  182 LEU B CA    1 
ATOM 1383 C C     . LEU A 1 182 ? 138.689 166.305 100.409 1.00 42.92  ?  182 LEU B C     1 
ATOM 1384 O O     . LEU A 1 182 ? 138.772 167.415 100.941 1.00 42.92  ?  182 LEU B O     1 
ATOM 1385 C CB    . LEU A 1 182 ? 137.505 164.487 101.648 1.00 42.92  ?  182 LEU B CB    1 
ATOM 1386 C CG    . LEU A 1 182 ? 137.458 163.156 102.400 1.00 42.92  ?  182 LEU B CG    1 
ATOM 1387 C CD1   . LEU A 1 182 ? 137.479 163.337 103.900 1.00 42.92  ?  182 LEU B CD1   1 
ATOM 1388 C CD2   . LEU A 1 182 ? 136.216 162.392 101.982 1.00 42.92  ?  182 LEU B CD2   1 
ATOM 1389 N N     . SER A 1 183 ? 138.440 166.138 99.115  1.00 57.18  ?  183 SER B N     1 
ATOM 1390 C CA    . SER A 1 183 ? 138.274 167.248 98.188  1.00 57.18  ?  183 SER B CA    1 
ATOM 1391 C C     . SER A 1 183 ? 136.793 167.460 97.920  1.00 57.18  ?  183 SER B C     1 
ATOM 1392 O O     . SER A 1 183 ? 136.054 166.494 97.704  1.00 57.18  ?  183 SER B O     1 
ATOM 1393 C CB    . SER A 1 183 ? 139.017 166.983 96.877  1.00 57.18  ?  183 SER B CB    1 
ATOM 1394 O OG    . SER A 1 183 ? 140.343 166.546 97.121  1.00 57.18  ?  183 SER B OG    1 
ATOM 1395 N N     . GLN A 1 184 ? 136.364 168.719 97.941  1.00 64.08  ?  184 GLN B N     1 
ATOM 1396 C CA    . GLN A 1 184 ? 134.960 169.041 97.724  1.00 64.08  ?  184 GLN B CA    1 
ATOM 1397 C C     . GLN A 1 184 ? 134.528 168.643 96.317  1.00 64.08  ?  184 GLN B C     1 
ATOM 1398 O O     . GLN A 1 184 ? 135.221 168.933 95.337  1.00 64.08  ?  184 GLN B O     1 
ATOM 1399 C CB    . GLN A 1 184 ? 134.720 170.532 97.947  1.00 64.08  ?  184 GLN B CB    1 
ATOM 1400 C CG    . GLN A 1 184 ? 133.283 170.965 97.731  1.00 64.08  ?  184 GLN B CG    1 
ATOM 1401 C CD    . GLN A 1 184 ? 133.054 172.416 98.093  1.00 64.08  ?  184 GLN B CD    1 
ATOM 1402 O OE1   . GLN A 1 184 ? 133.838 173.015 98.829  1.00 64.08  ?  184 GLN B OE1   1 
ATOM 1403 N NE2   . GLN A 1 184 ? 131.976 172.992 97.576  1.00 64.08  ?  184 GLN B NE2   1 
ATOM 1404 N N     . THR A 1 185 ? 133.380 167.977 96.221  1.00 79.66  ?  185 THR B N     1 
ATOM 1405 C CA    . THR A 1 185 ? 132.796 167.576 94.950  1.00 79.66  ?  185 THR B CA    1 
ATOM 1406 C C     . THR A 1 185 ? 131.378 168.119 94.850  1.00 79.66  ?  185 THR B C     1 
ATOM 1407 O O     . THR A 1 185 ? 130.621 168.084 95.824  1.00 79.66  ?  185 THR B O     1 
ATOM 1408 C CB    . THR A 1 185 ? 132.765 166.051 94.788  1.00 79.66  ?  185 THR B CB    1 
ATOM 1409 O OG1   . THR A 1 185 ? 131.551 165.536 95.349  1.00 79.66  ?  185 THR B OG1   1 
ATOM 1410 C CG2   . THR A 1 185 ? 133.950 165.408 95.483  1.00 79.66  ?  185 THR B CG2   1 
ATOM 1411 N N     . SER A 1 186 ? 131.027 168.615 93.678  1.00 109.77 ?  186 SER B N     1 
ATOM 1412 C CA    . SER A 1 186 ? 129.687 169.138 93.439  1.00 109.77 ?  186 SER B CA    1 
ATOM 1413 C C     . SER A 1 186 ? 129.026 168.538 92.208  1.00 109.77 ?  186 SER B C     1 
ATOM 1414 O O     . SER A 1 186 ? 127.810 168.331 92.211  1.00 109.77 ?  186 SER B O     1 
ATOM 1415 C CB    . SER A 1 186 ? 129.737 170.669 93.306  1.00 109.77 ?  186 SER B CB    1 
ATOM 1416 O OG    . SER A 1 186 ? 130.667 171.062 92.312  1.00 109.77 ?  186 SER B OG    1 
ATOM 1417 N N     . ASN A 1 187 ? 129.795 168.252 91.158  1.00 121.24 ?  187 ASN B N     1 
ATOM 1418 C CA    . ASN A 1 187 ? 129.241 167.742 89.903  1.00 121.24 ?  187 ASN B CA    1 
ATOM 1419 C C     . ASN A 1 187 ? 129.169 166.216 89.952  1.00 121.24 ?  187 ASN B C     1 
ATOM 1420 O O     . ASN A 1 187 ? 129.860 165.495 89.230  1.00 121.24 ?  187 ASN B O     1 
ATOM 1421 C CB    . ASN A 1 187 ? 130.073 168.229 88.724  1.00 121.24 ?  187 ASN B CB    1 
ATOM 1422 C CG    . ASN A 1 187 ? 131.554 168.282 89.042  1.00 121.24 ?  187 ASN B CG    1 
ATOM 1423 O OD1   . ASN A 1 187 ? 132.013 169.160 89.772  1.00 121.24 ?  187 ASN B OD1   1 
ATOM 1424 N ND2   . ASN A 1 187 ? 132.311 167.338 88.495  1.00 121.24 ?  187 ASN B ND2   1 
ATOM 1425 N N     . VAL A 1 188 ? 128.301 165.728 90.834  1.00 126.26 ?  188 VAL B N     1 
ATOM 1426 C CA    . VAL A 1 188 ? 128.041 164.302 90.986  1.00 126.26 ?  188 VAL B CA    1 
ATOM 1427 C C     . VAL A 1 188 ? 126.553 164.067 90.773  1.00 126.26 ?  188 VAL B C     1 
ATOM 1428 O O     . VAL A 1 188 ? 125.720 164.734 91.397  1.00 126.26 ?  188 VAL B O     1 
ATOM 1429 C CB    . VAL A 1 188 ? 128.485 163.783 92.366  1.00 126.26 ?  188 VAL B CB    1 
ATOM 1430 C CG1   . VAL A 1 188 ? 128.276 162.280 92.457  1.00 126.26 ?  188 VAL B CG1   1 
ATOM 1431 C CG2   . VAL A 1 188 ? 129.941 164.139 92.625  1.00 126.26 ?  188 VAL B CG2   1 
ATOM 1432 N N     . ASP A 1 189 ? 126.224 163.124 89.886  1.00 139.72 ?  189 ASP B N     1 
ATOM 1433 C CA    . ASP A 1 189 ? 124.822 162.844 89.589  1.00 139.72 ?  189 ASP B CA    1 
ATOM 1434 C C     . ASP A 1 189 ? 124.088 162.320 90.817  1.00 139.72 ?  189 ASP B C     1 
ATOM 1435 O O     . ASP A 1 189 ? 122.953 162.727 91.091  1.00 139.72 ?  189 ASP B O     1 
ATOM 1436 C CB    . ASP A 1 189 ? 124.721 161.848 88.434  1.00 139.72 ?  189 ASP B CB    1 
ATOM 1437 C CG    . ASP A 1 189 ? 125.437 160.543 88.724  1.00 139.72 ?  189 ASP B CG    1 
ATOM 1438 O OD1   . ASP A 1 189 ? 126.461 160.572 89.440  1.00 139.72 ?  189 ASP B OD1   1 
ATOM 1439 O OD2   . ASP A 1 189 ? 124.976 159.488 88.240  1.00 139.72 -1 189 ASP B OD2   1 
ATOM 1440 N N     . LYS A 1 190 ? 124.716 161.422 91.566  1.00 124.19 ?  190 LYS B N     1 
ATOM 1441 C CA    . LYS A 1 190 ? 124.111 160.853 92.758  1.00 124.19 ?  190 LYS B CA    1 
ATOM 1442 C C     . LYS A 1 190 ? 124.450 161.696 93.983  1.00 124.19 ?  190 LYS B C     1 
ATOM 1443 O O     . LYS A 1 190 ? 125.444 162.424 94.016  1.00 124.19 ?  190 LYS B O     1 
ATOM 1444 C CB    . LYS A 1 190 ? 124.579 159.412 92.965  1.00 124.19 ?  190 LYS B CB    1 
ATOM 1445 C CG    . LYS A 1 190 ? 126.020 159.289 93.431  1.00 124.19 ?  190 LYS B CG    1 
ATOM 1446 C CD    . LYS A 1 190 ? 126.619 157.952 93.030  1.00 124.19 ?  190 LYS B CD    1 
ATOM 1447 C CE    . LYS A 1 190 ? 126.929 157.914 91.543  1.00 124.19 ?  190 LYS B CE    1 
ATOM 1448 N NZ    . LYS A 1 190 ? 127.945 158.934 91.164  1.00 124.19 1  190 LYS B NZ    1 
ATOM 1449 N N     . GLU A 1 191 ? 123.596 161.594 94.997  1.00 110.73 ?  191 GLU B N     1 
ATOM 1450 C CA    . GLU A 1 191 ? 123.817 162.281 96.261  1.00 110.73 ?  191 GLU B CA    1 
ATOM 1451 C C     . GLU A 1 191 ? 124.560 161.422 97.274  1.00 110.73 ?  191 GLU B C     1 
ATOM 1452 O O     . GLU A 1 191 ? 124.832 161.891 98.384  1.00 110.73 ?  191 GLU B O     1 
ATOM 1453 C CB    . GLU A 1 191 ? 122.482 162.743 96.850  1.00 110.73 ?  191 GLU B CB    1 
ATOM 1454 C CG    . GLU A 1 191 ? 121.813 163.860 96.063  1.00 110.73 ?  191 GLU B CG    1 
ATOM 1455 C CD    . GLU A 1 191 ? 122.805 164.687 95.265  1.00 110.73 ?  191 GLU B CD    1 
ATOM 1456 O OE1   . GLU A 1 191 ? 123.495 165.536 95.868  1.00 110.73 ?  191 GLU B OE1   1 
ATOM 1457 O OE2   . GLU A 1 191 ? 122.893 164.489 94.034  1.00 110.73 -1 191 GLU B OE2   1 
ATOM 1458 N N     . GLU A 1 192 ? 124.894 160.182 96.920  1.00 91.97  ?  192 GLU B N     1 
ATOM 1459 C CA    . GLU A 1 192 ? 125.656 159.312 97.805  1.00 91.97  ?  192 GLU B CA    1 
ATOM 1460 C C     . GLU A 1 192 ? 127.145 159.629 97.804  1.00 91.97  ?  192 GLU B C     1 
ATOM 1461 O O     . GLU A 1 192 ? 127.863 159.148 98.686  1.00 91.97  ?  192 GLU B O     1 
ATOM 1462 C CB    . GLU A 1 192 ? 125.440 157.848 97.410  1.00 91.97  ?  192 GLU B CB    1 
ATOM 1463 C CG    . GLU A 1 192 ? 125.723 156.848 98.520  1.00 91.97  ?  192 GLU B CG    1 
ATOM 1464 C CD    . GLU A 1 192 ? 127.089 156.204 98.388  1.00 91.97  ?  192 GLU B CD    1 
ATOM 1465 O OE1   . GLU A 1 192 ? 127.772 156.460 97.374  1.00 91.97  ?  192 GLU B OE1   1 
ATOM 1466 O OE2   . GLU A 1 192 ? 127.481 155.443 99.297  1.00 91.97  -1 192 GLU B OE2   1 
ATOM 1467 N N     . GLU A 1 193 ? 127.624 160.424 96.847  1.00 82.78  ?  193 GLU B N     1 
ATOM 1468 C CA    . GLU A 1 193 ? 129.038 160.767 96.759  1.00 82.78  ?  193 GLU B CA    1 
ATOM 1469 C C     . GLU A 1 193 ? 129.298 162.246 97.010  1.00 82.78  ?  193 GLU B C     1 
ATOM 1470 O O     . GLU A 1 193 ? 130.446 162.691 96.900  1.00 82.78  ?  193 GLU B O     1 
ATOM 1471 C CB    . GLU A 1 193 ? 129.596 160.360 95.391  1.00 82.78  ?  193 GLU B CB    1 
ATOM 1472 C CG    . GLU A 1 193 ? 131.070 159.986 95.402  1.00 82.78  ?  193 GLU B CG    1 
ATOM 1473 C CD    . GLU A 1 193 ? 131.370 158.814 96.316  1.00 82.78  ?  193 GLU B CD    1 
ATOM 1474 O OE1   . GLU A 1 193 ? 130.498 157.931 96.463  1.00 82.78  ?  193 GLU B OE1   1 
ATOM 1475 O OE2   . GLU A 1 193 ? 132.479 158.775 96.887  1.00 82.78  -1 193 GLU B OE2   1 
ATOM 1476 N N     . ALA A 1 194 ? 128.270 163.018 97.348  1.00 64.33  ?  194 ALA B N     1 
ATOM 1477 C CA    . ALA A 1 194 ? 128.447 164.439 97.604  1.00 64.33  ?  194 ALA B CA    1 
ATOM 1478 C C     . ALA A 1 194 ? 129.166 164.657 98.927  1.00 64.33  ?  194 ALA B C     1 
ATOM 1479 O O     . ALA A 1 194 ? 128.851 164.021 99.936  1.00 64.33  ?  194 ALA B O     1 
ATOM 1480 C CB    . ALA A 1 194 ? 127.095 165.151 97.618  1.00 64.33  ?  194 ALA B CB    1 
ATOM 1481 N N     . VAL A 1 195 ? 130.145 165.558 98.914  1.00 49.85  ?  195 VAL B N     1 
ATOM 1482 C CA    . VAL A 1 195 ? 130.885 165.921 100.117 1.00 49.85  ?  195 VAL B CA    1 
ATOM 1483 C C     . VAL A 1 195 ? 130.750 167.429 100.310 1.00 49.85  ?  195 VAL B C     1 
ATOM 1484 O O     . VAL A 1 195 ? 131.652 168.097 100.830 1.00 49.85  ?  195 VAL B O     1 
ATOM 1485 C CB    . VAL A 1 195 ? 132.350 165.447 100.024 1.00 49.85  ?  195 VAL B CB    1 
ATOM 1486 C CG1   . VAL A 1 195 ? 133.108 166.212 98.958  1.00 49.85  ?  195 VAL B CG1   1 
ATOM 1487 C CG2   . VAL A 1 195 ? 133.049 165.506 101.383 1.00 49.85  ?  195 VAL B CG2   1 
ATOM 1488 N N     . THR A 1 196 ? 129.602 167.967 99.901  1.00 48.13  ?  196 THR B N     1 
ATOM 1489 C CA    . THR A 1 196 ? 129.372 169.406 99.928  1.00 48.13  ?  196 THR B CA    1 
ATOM 1490 C C     . THR A 1 196 ? 129.553 169.975 101.330 1.00 48.13  ?  196 THR B C     1 
ATOM 1491 O O     . THR A 1 196 ? 129.076 169.410 102.317 1.00 48.13  ?  196 THR B O     1 
ATOM 1492 C CB    . THR A 1 196 ? 127.963 169.718 99.422  1.00 48.13  ?  196 THR B CB    1 
ATOM 1493 O OG1   . THR A 1 196 ? 127.765 169.100 98.145  1.00 48.13  ?  196 THR B OG1   1 
ATOM 1494 C CG2   . THR A 1 196 ? 127.762 171.219 99.287  1.00 48.13  ?  196 THR B CG2   1 
ATOM 1495 N N     . ILE A 1 197 ? 130.252 171.105 101.408 1.00 50.00  ?  197 ILE B N     1 
ATOM 1496 C CA    . ILE A 1 197 ? 130.512 171.805 102.660 1.00 50.00  ?  197 ILE B CA    1 
ATOM 1497 C C     . ILE A 1 197 ? 129.992 173.230 102.536 1.00 50.00  ?  197 ILE B C     1 
ATOM 1498 O O     . ILE A 1 197 ? 130.254 173.908 101.536 1.00 50.00  ?  197 ILE B O     1 
ATOM 1499 C CB    . ILE A 1 197 ? 132.011 171.799 103.015 1.00 50.00  ?  197 ILE B CB    1 
ATOM 1500 C CG1   . ILE A 1 197 ? 132.283 172.733 104.196 1.00 50.00  ?  197 ILE B CG1   1 
ATOM 1501 C CG2   . ILE A 1 197 ? 132.855 172.180 101.810 1.00 50.00  ?  197 ILE B CG2   1 
ATOM 1502 C CD1   . ILE A 1 197 ? 133.709 172.701 104.686 1.00 50.00  ?  197 ILE B CD1   1 
ATOM 1503 N N     . GLU A 1 198 ? 129.247 173.675 103.542 1.00 58.54  ?  198 GLU B N     1 
ATOM 1504 C CA    . GLU A 1 198 ? 128.752 175.042 103.613 1.00 58.54  ?  198 GLU B CA    1 
ATOM 1505 C C     . GLU A 1 198 ? 129.376 175.739 104.814 1.00 58.54  ?  198 GLU B C     1 
ATOM 1506 O O     . GLU A 1 198 ? 129.280 175.245 105.943 1.00 58.54  ?  198 GLU B O     1 
ATOM 1507 C CB    . GLU A 1 198 ? 127.226 175.068 103.711 1.00 58.54  ?  198 GLU B CB    1 
ATOM 1508 C CG    . GLU A 1 198 ? 126.630 176.463 103.759 1.00 58.54  ?  198 GLU B CG    1 
ATOM 1509 C CD    . GLU A 1 198 ? 126.369 176.935 105.175 1.00 58.54  ?  198 GLU B CD    1 
ATOM 1510 O OE1   . GLU A 1 198 ? 125.358 176.505 105.769 1.00 58.54  ?  198 GLU B OE1   1 
ATOM 1511 O OE2   . GLU A 1 198 ? 127.175 177.735 105.694 1.00 58.54  -1 198 GLU B OE2   1 
ATOM 1512 N N     . MET A 1 199 ? 130.004 176.884 104.569 1.00 67.18  ?  199 MET B N     1 
ATOM 1513 C CA    . MET A 1 199 ? 130.694 177.649 105.598 1.00 67.18  ?  199 MET B CA    1 
ATOM 1514 C C     . MET A 1 199 ? 130.119 179.049 105.733 1.00 67.18  ?  199 MET B C     1 
ATOM 1515 O O     . MET A 1 199 ? 129.726 179.675 104.743 1.00 67.18  ?  199 MET B O     1 
ATOM 1516 C CB    . MET A 1 199 ? 132.194 177.757 105.308 1.00 67.18  ?  199 MET B CB    1 
ATOM 1517 C CG    . MET A 1 199 ? 133.076 177.461 106.505 1.00 67.18  ?  199 MET B CG    1 
ATOM 1518 S SD    . MET A 1 199 ? 133.240 175.739 106.979 1.00 67.18  ?  199 MET B SD    1 
ATOM 1519 C CE    . MET A 1 199 ? 134.302 175.943 108.406 1.00 67.18  ?  199 MET B CE    1 
ATOM 1520 N N     . ASN A 1 200 ? 130.075 179.526 106.973 1.00 76.21  ?  200 ASN B N     1 
ATOM 1521 C CA    . ASN A 1 200 ? 129.870 180.933 107.286 1.00 76.21  ?  200 ASN B CA    1 
ATOM 1522 C C     . ASN A 1 200 ? 131.063 181.518 108.022 1.00 76.21  ?  200 ASN B C     1 
ATOM 1523 O O     . ASN A 1 200 ? 131.521 182.615 107.682 1.00 76.21  ?  200 ASN B O     1 
ATOM 1524 C CB    . ASN A 1 200 ? 128.591 181.113 108.119 1.00 76.21  ?  200 ASN B CB    1 
ATOM 1525 C CG    . ASN A 1 200 ? 128.541 180.186 109.317 1.00 76.21  ?  200 ASN B CG    1 
ATOM 1526 O OD1   . ASN A 1 200 ? 129.351 180.297 110.238 1.00 76.21  ?  200 ASN B OD1   1 
ATOM 1527 N ND2   . ASN A 1 200 ? 127.584 179.265 109.313 1.00 76.21  ?  200 ASN B ND2   1 
ATOM 1528 N N     . GLU A 1 201 ? 131.588 180.802 109.013 1.00 82.87  ?  201 GLU B N     1 
ATOM 1529 C CA    . GLU A 1 201 ? 132.761 181.176 109.783 1.00 82.87  ?  201 GLU B CA    1 
ATOM 1530 C C     . GLU A 1 201 ? 133.743 180.015 109.815 1.00 82.87  ?  201 GLU B C     1 
ATOM 1531 O O     . GLU A 1 201 ? 133.336 178.851 109.741 1.00 82.87  ?  201 GLU B O     1 
ATOM 1532 C CB    . GLU A 1 201 ? 132.384 181.559 111.222 1.00 82.87  ?  201 GLU B CB    1 
ATOM 1533 C CG    . GLU A 1 201 ? 132.244 183.051 111.472 1.00 82.87  ?  201 GLU B CG    1 
ATOM 1534 C CD    . GLU A 1 201 ? 131.404 183.744 110.422 1.00 82.87  ?  201 GLU B CD    1 
ATOM 1535 O OE1   . GLU A 1 201 ? 130.208 183.408 110.299 1.00 82.87  ?  201 GLU B OE1   1 
ATOM 1536 O OE2   . GLU A 1 201 ? 131.940 184.623 109.716 1.00 82.87  -1 201 GLU B OE2   1 
ATOM 1537 N N     . PRO A 1 202 ? 135.038 180.298 109.918 1.00 79.06  ?  202 PRO B N     1 
ATOM 1538 C CA    . PRO A 1 202 ? 136.017 179.218 110.083 1.00 79.06  ?  202 PRO B CA    1 
ATOM 1539 C C     . PRO A 1 202 ? 135.883 178.556 111.445 1.00 79.06  ?  202 PRO B C     1 
ATOM 1540 O O     . PRO A 1 202 ? 135.426 179.156 112.420 1.00 79.06  ?  202 PRO B O     1 
ATOM 1541 C CB    . PRO A 1 202 ? 137.364 179.933 109.942 1.00 79.06  ?  202 PRO B CB    1 
ATOM 1542 C CG    . PRO A 1 202 ? 137.076 181.349 110.314 1.00 79.06  ?  202 PRO B CG    1 
ATOM 1543 C CD    . PRO A 1 202 ? 135.682 181.620 109.831 1.00 79.06  ?  202 PRO B CD    1 
ATOM 1544 N N     . VAL A 1 203 ? 136.293 177.289 111.504 1.00 60.92  ?  203 VAL B N     1 
ATOM 1545 C CA    . VAL A 1 203 ? 136.182 176.505 112.727 1.00 60.92  ?  203 VAL B CA    1 
ATOM 1546 C C     . VAL A 1 203 ? 137.383 175.576 112.832 1.00 60.92  ?  203 VAL B C     1 
ATOM 1547 O O     . VAL A 1 203 ? 137.993 175.199 111.828 1.00 60.92  ?  203 VAL B O     1 
ATOM 1548 C CB    . VAL A 1 203 ? 134.855 175.710 112.769 1.00 60.92  ?  203 VAL B CB    1 
ATOM 1549 C CG1   . VAL A 1 203 ? 134.907 174.534 111.812 1.00 60.92  ?  203 VAL B CG1   1 
ATOM 1550 C CG2   . VAL A 1 203 ? 134.544 175.251 114.184 1.00 60.92  ?  203 VAL B CG2   1 
ATOM 1551 N N     . GLN A 1 204 ? 137.730 175.221 114.068 1.00 50.17  ?  204 GLN B N     1 
ATOM 1552 C CA    . GLN A 1 204 ? 138.789 174.256 114.346 1.00 50.17  ?  204 GLN B CA    1 
ATOM 1553 C C     . GLN A 1 204 ? 138.571 173.721 115.752 1.00 50.17  ?  204 GLN B C     1 
ATOM 1554 O O     . GLN A 1 204 ? 138.610 174.490 116.717 1.00 50.17  ?  204 GLN B O     1 
ATOM 1555 C CB    . GLN A 1 204 ? 140.173 174.891 114.216 1.00 50.17  ?  204 GLN B CB    1 
ATOM 1556 C CG    . GLN A 1 204 ? 141.271 174.116 114.919 1.00 50.17  ?  204 GLN B CG    1 
ATOM 1557 C CD    . GLN A 1 204 ? 142.654 174.608 114.553 1.00 50.17  ?  204 GLN B CD    1 
ATOM 1558 O OE1   . GLN A 1 204 ? 142.804 175.606 113.849 1.00 50.17  ?  204 GLN B OE1   1 
ATOM 1559 N NE2   . GLN A 1 204 ? 143.676 173.907 115.029 1.00 50.17  ?  204 GLN B NE2   1 
ATOM 1560 N N     . LEU A 1 205 ? 138.339 172.414 115.869 1.00 40.88  ?  205 LEU B N     1 
ATOM 1561 C CA    . LEU A 1 205 ? 137.945 171.837 117.148 1.00 40.88  ?  205 LEU B CA    1 
ATOM 1562 C C     . LEU A 1 205 ? 138.777 170.612 117.504 1.00 40.88  ?  205 LEU B C     1 
ATOM 1563 O O     . LEU A 1 205 ? 139.768 170.309 116.833 1.00 40.88  ?  205 LEU B O     1 
ATOM 1564 C CB    . LEU A 1 205 ? 136.460 171.474 117.121 1.00 40.88  ?  205 LEU B CB    1 
ATOM 1565 C CG    . LEU A 1 205 ? 135.512 172.589 116.676 1.00 40.88  ?  205 LEU B CG    1 
ATOM 1566 C CD1   . LEU A 1 205 ? 134.105 172.059 116.475 1.00 40.88  ?  205 LEU B CD1   1 
ATOM 1567 C CD2   . LEU A 1 205 ? 135.519 173.727 117.683 1.00 40.88  ?  205 LEU B CD2   1 
ATOM 1568 N N     . THR A 1 206 ? 138.384 169.909 118.564 1.00 41.45  ?  206 THR B N     1 
ATOM 1569 C CA    . THR A 1 206 ? 139.088 168.718 119.022 1.00 41.45  ?  206 THR B CA    1 
ATOM 1570 C C     . THR A 1 206 ? 138.088 167.789 119.691 1.00 41.45  ?  206 THR B C     1 
ATOM 1571 O O     . THR A 1 206 ? 137.263 168.243 120.488 1.00 41.45  ?  206 THR B O     1 
ATOM 1572 C CB    . THR A 1 206 ? 140.209 169.080 120.000 1.00 41.45  ?  206 THR B CB    1 
ATOM 1573 O OG1   . THR A 1 206 ? 141.060 170.069 119.410 1.00 41.45  ?  206 THR B OG1   1 
ATOM 1574 C CG2   . THR A 1 206 ? 141.032 167.853 120.345 1.00 41.45  ?  206 THR B CG2   1 
ATOM 1575 N N     . PHE A 1 207 ? 138.162 166.498 119.374 1.00 36.67  ?  207 PHE B N     1 
ATOM 1576 C CA    . PHE A 1 207 ? 137.219 165.525 119.904 1.00 36.67  ?  207 PHE B CA    1 
ATOM 1577 C C     . PHE A 1 207 ? 137.949 164.240 120.262 1.00 36.67  ?  207 PHE B C     1 
ATOM 1578 O O     . PHE A 1 207 ? 139.046 163.967 119.773 1.00 36.67  ?  207 PHE B O     1 
ATOM 1579 C CB    . PHE A 1 207 ? 136.097 165.222 118.906 1.00 36.67  ?  207 PHE B CB    1 
ATOM 1580 C CG    . PHE A 1 207 ? 135.412 166.443 118.379 1.00 36.67  ?  207 PHE B CG    1 
ATOM 1581 C CD1   . PHE A 1 207 ? 135.889 167.092 117.257 1.00 36.67  ?  207 PHE B CD1   1 
ATOM 1582 C CD2   . PHE A 1 207 ? 134.291 166.947 119.009 1.00 36.67  ?  207 PHE B CD2   1 
ATOM 1583 C CE1   . PHE A 1 207 ? 135.260 168.215 116.772 1.00 36.67  ?  207 PHE B CE1   1 
ATOM 1584 C CE2   . PHE A 1 207 ? 133.659 168.071 118.528 1.00 36.67  ?  207 PHE B CE2   1 
ATOM 1585 C CZ    . PHE A 1 207 ? 134.144 168.705 117.408 1.00 36.67  ?  207 PHE B CZ    1 
ATOM 1586 N N     . ALA A 1 208 ? 137.320 163.450 121.127 1.00 40.99  ?  208 ALA B N     1 
ATOM 1587 C CA    . ALA A 1 208 ? 137.868 162.159 121.516 1.00 40.99  ?  208 ALA B CA    1 
ATOM 1588 C C     . ALA A 1 208 ? 137.522 161.112 120.466 1.00 40.99  ?  208 ALA B C     1 
ATOM 1589 O O     . ALA A 1 208 ? 136.375 161.026 120.018 1.00 40.99  ?  208 ALA B O     1 
ATOM 1590 C CB    . ALA A 1 208 ? 137.333 161.740 122.884 1.00 40.99  ?  208 ALA B CB    1 
ATOM 1591 N N     . LEU A 1 209 ? 138.517 160.315 120.075 1.00 41.11  ?  209 LEU B N     1 
ATOM 1592 C CA    . LEU A 1 209 ? 138.313 159.367 118.985 1.00 41.11  ?  209 LEU B CA    1 
ATOM 1593 C C     . LEU A 1 209 ? 137.489 158.163 119.416 1.00 41.11  ?  209 LEU B C     1 
ATOM 1594 O O     . LEU A 1 209 ? 136.801 157.560 118.584 1.00 41.11  ?  209 LEU B O     1 
ATOM 1595 C CB    . LEU A 1 209 ? 139.657 158.913 118.425 1.00 41.11  ?  209 LEU B CB    1 
ATOM 1596 C CG    . LEU A 1 209 ? 139.958 159.460 117.032 1.00 41.11  ?  209 LEU B CG    1 
ATOM 1597 C CD1   . LEU A 1 209 ? 141.293 158.954 116.534 1.00 41.11  ?  209 LEU B CD1   1 
ATOM 1598 C CD2   . LEU A 1 209 ? 138.850 159.083 116.071 1.00 41.11  ?  209 LEU B CD2   1 
ATOM 1599 N N     . ARG A 1 210 ? 137.551 157.786 120.694 1.00 47.45  ?  210 ARG B N     1 
ATOM 1600 C CA    . ARG A 1 210 ? 136.751 156.659 121.162 1.00 47.45  ?  210 ARG B CA    1 
ATOM 1601 C C     . ARG A 1 210 ? 135.264 156.936 120.990 1.00 47.45  ?  210 ARG B C     1 
ATOM 1602 O O     . ARG A 1 210 ? 134.504 156.065 120.544 1.00 47.45  ?  210 ARG B O     1 
ATOM 1603 C CB    . ARG A 1 210 ? 137.074 156.359 122.624 1.00 47.45  ?  210 ARG B CB    1 
ATOM 1604 C CG    . ARG A 1 210 ? 136.792 154.928 123.042 1.00 47.45  ?  210 ARG B CG    1 
ATOM 1605 C CD    . ARG A 1 210 ? 137.191 154.688 124.489 1.00 47.45  ?  210 ARG B CD    1 
ATOM 1606 N NE    . ARG A 1 210 ? 136.215 155.236 125.423 1.00 47.45  ?  210 ARG B NE    1 
ATOM 1607 C CZ    . ARG A 1 210 ? 136.333 156.410 126.029 1.00 47.45  ?  210 ARG B CZ    1 
ATOM 1608 N NH1   . ARG A 1 210 ? 137.384 157.188 125.830 1.00 47.45  1  210 ARG B NH1   1 
ATOM 1609 N NH2   . ARG A 1 210 ? 135.372 156.812 126.856 1.00 47.45  ?  210 ARG B NH2   1 
ATOM 1610 N N     . TYR A 1 211 ? 134.831 158.151 121.323 1.00 49.38  ?  211 TYR B N     1 
ATOM 1611 C CA    . TYR A 1 211 ? 133.425 158.493 121.165 1.00 49.38  ?  211 TYR B CA    1 
ATOM 1612 C C     . TYR A 1 211 ? 133.025 158.533 119.696 1.00 49.38  ?  211 TYR B C     1 
ATOM 1613 O O     . TYR A 1 211 ? 131.908 158.144 119.346 1.00 49.38  ?  211 TYR B O     1 
ATOM 1614 C CB    . TYR A 1 211 ? 133.128 159.823 121.853 1.00 49.38  ?  211 TYR B CB    1 
ATOM 1615 C CG    . TYR A 1 211 ? 133.086 159.704 123.357 1.00 49.38  ?  211 TYR B CG    1 
ATOM 1616 C CD1   . TYR A 1 211 ? 132.190 158.845 123.976 1.00 49.38  ?  211 TYR B CD1   1 
ATOM 1617 C CD2   . TYR A 1 211 ? 133.948 160.439 124.157 1.00 49.38  ?  211 TYR B CD2   1 
ATOM 1618 C CE1   . TYR A 1 211 ? 132.148 158.725 125.350 1.00 49.38  ?  211 TYR B CE1   1 
ATOM 1619 C CE2   . TYR A 1 211 ? 133.914 160.326 125.534 1.00 49.38  ?  211 TYR B CE2   1 
ATOM 1620 C CZ    . TYR A 1 211 ? 133.012 159.467 126.124 1.00 49.38  ?  211 TYR B CZ    1 
ATOM 1621 O OH    . TYR A 1 211 ? 132.974 159.351 127.494 1.00 49.38  ?  211 TYR B OH    1 
ATOM 1622 N N     . LEU A 1 212 ? 133.920 158.987 118.816 1.00 40.58  ?  212 LEU B N     1 
ATOM 1623 C CA    . LEU A 1 212 ? 133.600 158.979 117.391 1.00 40.58  ?  212 LEU B CA    1 
ATOM 1624 C C     . LEU A 1 212 ? 133.480 157.556 116.859 1.00 40.58  ?  212 LEU B C     1 
ATOM 1625 O O     . LEU A 1 212 ? 132.610 157.267 116.026 1.00 40.58  ?  212 LEU B O     1 
ATOM 1626 C CB    . LEU A 1 212 ? 134.651 159.762 116.609 1.00 40.58  ?  212 LEU B CB    1 
ATOM 1627 C CG    . LEU A 1 212 ? 134.530 161.283 116.693 1.00 40.58  ?  212 LEU B CG    1 
ATOM 1628 C CD1   . LEU A 1 212 ? 135.344 161.945 115.599 1.00 40.58  ?  212 LEU B CD1   1 
ATOM 1629 C CD2   . LEU A 1 212 ? 133.077 161.707 116.609 1.00 40.58  ?  212 LEU B CD2   1 
ATOM 1630 N N     . ASN A 1 213 ? 134.347 156.654 117.322 1.00 41.62  ?  213 ASN B N     1 
ATOM 1631 C CA    . ASN A 1 213 ? 134.236 155.257 116.920 1.00 41.62  ?  213 ASN B CA    1 
ATOM 1632 C C     . ASN A 1 213 ? 132.939 154.645 117.429 1.00 41.62  ?  213 ASN B C     1 
ATOM 1633 O O     . ASN A 1 213 ? 132.316 153.830 116.739 1.00 41.62  ?  213 ASN B O     1 
ATOM 1634 C CB    . ASN A 1 213 ? 135.439 154.465 117.424 1.00 41.62  ?  213 ASN B CB    1 
ATOM 1635 C CG    . ASN A 1 213 ? 136.659 154.649 116.551 1.00 41.62  ?  213 ASN B CG    1 
ATOM 1636 O OD1   . ASN A 1 213 ? 136.547 155.000 115.377 1.00 41.62  ?  213 ASN B OD1   1 
ATOM 1637 N ND2   . ASN A 1 213 ? 137.834 154.413 117.119 1.00 41.62  ?  213 ASN B ND2   1 
ATOM 1638 N N     . PHE A 1 214 ? 132.522 155.016 118.641 1.00 43.65  ?  214 PHE B N     1 
ATOM 1639 C CA    . PHE A 1 214 ? 131.218 154.580 119.131 1.00 43.65  ?  214 PHE B CA    1 
ATOM 1640 C C     . PHE A 1 214 ? 130.092 155.134 118.266 1.00 43.65  ?  214 PHE B C     1 
ATOM 1641 O O     . PHE A 1 214 ? 129.117 154.432 117.975 1.00 43.65  ?  214 PHE B O     1 
ATOM 1642 C CB    . PHE A 1 214 ? 131.029 155.008 120.585 1.00 43.65  ?  214 PHE B CB    1 
ATOM 1643 C CG    . PHE A 1 214 ? 131.770 154.155 121.569 1.00 43.65  ?  214 PHE B CG    1 
ATOM 1644 C CD1   . PHE A 1 214 ? 132.114 152.853 121.254 1.00 43.65  ?  214 PHE B CD1   1 
ATOM 1645 C CD2   . PHE A 1 214 ? 132.117 154.653 122.811 1.00 43.65  ?  214 PHE B CD2   1 
ATOM 1646 C CE1   . PHE A 1 214 ? 132.795 152.066 122.158 1.00 43.65  ?  214 PHE B CE1   1 
ATOM 1647 C CE2   . PHE A 1 214 ? 132.797 153.871 123.720 1.00 43.65  ?  214 PHE B CE2   1 
ATOM 1648 C CZ    . PHE A 1 214 ? 133.137 152.575 123.393 1.00 43.65  ?  214 PHE B CZ    1 
ATOM 1649 N N     . PHE A 1 215 ? 130.209 156.398 117.856 1.00 39.01  ?  215 PHE B N     1 
ATOM 1650 C CA    . PHE A 1 215 ? 129.162 157.031 117.061 1.00 39.01  ?  215 PHE B CA    1 
ATOM 1651 C C     . PHE A 1 215 ? 129.011 156.354 115.708 1.00 39.01  ?  215 PHE B C     1 
ATOM 1652 O O     . PHE A 1 215 ? 127.890 156.132 115.238 1.00 39.01  ?  215 PHE B O     1 
ATOM 1653 C CB    . PHE A 1 215 ? 129.470 158.516 116.864 1.00 39.01  ?  215 PHE B CB    1 
ATOM 1654 C CG    . PHE A 1 215 ? 129.401 159.333 118.122 1.00 39.01  ?  215 PHE B CG    1 
ATOM 1655 C CD1   . PHE A 1 215 ? 128.941 158.787 119.306 1.00 39.01  ?  215 PHE B CD1   1 
ATOM 1656 C CD2   . PHE A 1 215 ? 129.795 160.658 118.113 1.00 39.01  ?  215 PHE B CD2   1 
ATOM 1657 C CE1   . PHE A 1 215 ? 128.879 159.545 120.455 1.00 39.01  ?  215 PHE B CE1   1 
ATOM 1658 C CE2   . PHE A 1 215 ? 129.735 161.420 119.259 1.00 39.01  ?  215 PHE B CE2   1 
ATOM 1659 C CZ    . PHE A 1 215 ? 129.276 160.863 120.431 1.00 39.01  ?  215 PHE B CZ    1 
ATOM 1660 N N     . THR A 1 216 ? 130.125 156.022 115.066 1.00 35.97  ?  216 THR B N     1 
ATOM 1661 C CA    . THR A 1 216 ? 130.057 155.476 113.710 1.00 35.97  ?  216 THR B CA    1 
ATOM 1662 C C     . THR A 1 216 ? 129.547 154.045 113.656 1.00 35.97  ?  216 THR B C     1 
ATOM 1663 O O     . THR A 1 216 ? 129.600 153.457 112.570 1.00 35.97  ?  216 THR B O     1 
ATOM 1664 C CB    . THR A 1 216 ? 131.424 155.551 113.035 1.00 35.97  ?  216 THR B CB    1 
ATOM 1665 O OG1   . THR A 1 216 ? 132.436 155.124 113.954 1.00 35.97  ?  216 THR B OG1   1 
ATOM 1666 C CG2   . THR A 1 216 ? 131.712 156.971 112.588 1.00 35.97  ?  216 THR B CG2   1 
ATOM 1667 N N     . LYS A 1 217 ? 129.064 153.449 114.747 1.00 36.87  ?  217 LYS B N     1 
ATOM 1668 C CA    . LYS A 1 217 ? 128.452 152.129 114.664 1.00 36.87  ?  217 LYS B CA    1 
ATOM 1669 C C     . LYS A 1 217 ? 127.122 152.149 113.926 1.00 36.87  ?  217 LYS B C     1 
ATOM 1670 O O     . LYS A 1 217 ? 126.626 151.082 113.551 1.00 36.87  ?  217 LYS B O     1 
ATOM 1671 C CB    . LYS A 1 217 ? 128.251 151.550 116.064 1.00 36.87  ?  217 LYS B CB    1 
ATOM 1672 C CG    . LYS A 1 217 ? 129.538 151.279 116.817 1.00 36.87  ?  217 LYS B CG    1 
ATOM 1673 C CD    . LYS A 1 217 ? 130.460 150.372 116.023 1.00 36.87  ?  217 LYS B CD    1 
ATOM 1674 C CE    . LYS A 1 217 ? 131.316 149.519 116.944 1.00 36.87  ?  217 LYS B CE    1 
ATOM 1675 N NZ    . LYS A 1 217 ? 132.712 150.029 117.033 1.00 36.87  1  217 LYS B NZ    1 
ATOM 1676 N N     . ALA A 1 218 ? 126.536 153.327 113.711 1.00 31.43  ?  218 ALA B N     1 
ATOM 1677 C CA    . ALA A 1 218 ? 125.261 153.462 113.019 1.00 31.43  ?  218 ALA B CA    1 
ATOM 1678 C C     . ALA A 1 218 ? 125.429 153.711 111.527 1.00 31.43  ?  218 ALA B C     1 
ATOM 1679 O O     . ALA A 1 218 ? 124.567 154.348 110.908 1.00 31.43  ?  218 ALA B O     1 
ATOM 1680 C CB    . ALA A 1 218 ? 124.437 154.580 113.655 1.00 31.43  ?  218 ALA B CB    1 
ATOM 1681 N N     . THR A 1 219 ? 126.524 153.237 110.937 1.00 30.06  ?  219 THR B N     1 
ATOM 1682 C CA    . THR A 1 219 ? 126.733 153.410 109.500 1.00 30.06  ?  219 THR B CA    1 
ATOM 1683 C C     . THR A 1 219 ? 125.653 152.754 108.646 1.00 30.06  ?  219 THR B C     1 
ATOM 1684 O O     . THR A 1 219 ? 125.179 153.402 107.697 1.00 30.06  ?  219 THR B O     1 
ATOM 1685 C CB    . THR A 1 219 ? 128.125 152.895 109.120 1.00 30.06  ?  219 THR B CB    1 
ATOM 1686 O OG1   . THR A 1 219 ? 129.119 153.628 109.844 1.00 30.06  ?  219 THR B OG1   1 
ATOM 1687 C CG2   . THR A 1 219 ? 128.366 153.066 107.631 1.00 30.06  ?  219 THR B CG2   1 
ATOM 1688 N N     . PRO A 1 220 ? 125.221 151.511 108.896 1.00 27.90  ?  220 PRO B N     1 
ATOM 1689 C CA    . PRO A 1 220 ? 124.247 150.884 107.986 1.00 27.90  ?  220 PRO B CA    1 
ATOM 1690 C C     . PRO A 1 220 ? 122.901 151.587 107.923 1.00 27.90  ?  220 PRO B C     1 
ATOM 1691 O O     . PRO A 1 220 ? 122.127 151.303 107.001 1.00 27.90  ?  220 PRO B O     1 
ATOM 1692 C CB    . PRO A 1 220 ? 124.098 149.464 108.550 1.00 27.90  ?  220 PRO B CB    1 
ATOM 1693 C CG    . PRO A 1 220 ? 125.326 149.238 109.342 1.00 27.90  ?  220 PRO B CG    1 
ATOM 1694 C CD    . PRO A 1 220 ? 125.651 150.564 109.940 1.00 27.90  ?  220 PRO B CD    1 
ATOM 1695 N N     . LEU A 1 221 ? 122.589 152.476 108.869 1.00 29.09  ?  221 LEU B N     1 
ATOM 1696 C CA    . LEU A 1 221 ? 121.276 153.113 108.879 1.00 29.09  ?  221 LEU B CA    1 
ATOM 1697 C C     . LEU A 1 221 ? 121.050 153.952 107.628 1.00 29.09  ?  221 LEU B C     1 
ATOM 1698 O O     . LEU A 1 221 ? 119.962 153.921 107.042 1.00 29.09  ?  221 LEU B O     1 
ATOM 1699 C CB    . LEU A 1 221 ? 121.119 153.970 110.132 1.00 29.09  ?  221 LEU B CB    1 
ATOM 1700 C CG    . LEU A 1 221 ? 120.907 153.183 111.422 1.00 29.09  ?  221 LEU B CG    1 
ATOM 1701 C CD1   . LEU A 1 221 ? 121.010 154.093 112.626 1.00 29.09  ?  221 LEU B CD1   1 
ATOM 1702 C CD2   . LEU A 1 221 ? 119.562 152.485 111.392 1.00 29.09  ?  221 LEU B CD2   1 
ATOM 1703 N N     . SER A 1 222 ? 122.057 154.707 107.204 1.00 28.48  ?  222 SER B N     1 
ATOM 1704 C CA    . SER A 1 222 ? 121.927 155.559 106.032 1.00 28.48  ?  222 SER B CA    1 
ATOM 1705 C C     . SER A 1 222 ? 123.287 155.659 105.354 1.00 28.48  ?  222 SER B C     1 
ATOM 1706 O O     . SER A 1 222 ? 124.197 154.872 105.628 1.00 28.48  ?  222 SER B O     1 
ATOM 1707 C CB    . SER A 1 222 ? 121.374 156.935 106.418 1.00 28.48  ?  222 SER B CB    1 
ATOM 1708 O OG    . SER A 1 222 ? 121.340 157.796 105.294 1.00 28.48  ?  222 SER B OG    1 
ATOM 1709 N N     . SER A 1 223 ? 123.425 156.634 104.453 1.00 31.48  ?  223 SER B N     1 
ATOM 1710 C CA    . SER A 1 223 ? 124.680 156.805 103.733 1.00 31.48  ?  223 SER B CA    1 
ATOM 1711 C C     . SER A 1 223 ? 125.088 158.269 103.616 1.00 31.48  ?  223 SER B C     1 
ATOM 1712 O O     . SER A 1 223 ? 125.897 158.607 102.745 1.00 31.48  ?  223 SER B O     1 
ATOM 1713 C CB    . SER A 1 223 ? 124.589 156.187 102.335 1.00 31.48  ?  223 SER B CB    1 
ATOM 1714 O OG    . SER A 1 223 ? 123.489 156.716 101.618 1.00 31.48  ?  223 SER B OG    1 
ATOM 1715 N N     . THR A 1 224 ? 124.557 159.148 104.467 1.00 28.74  ?  224 THR B N     1 
ATOM 1716 C CA    . THR A 1 224 ? 124.861 160.580 104.402 1.00 28.74  ?  224 THR B CA    1 
ATOM 1717 C C     . THR A 1 224 ? 124.965 161.117 105.828 1.00 28.74  ?  224 THR B C     1 
ATOM 1718 O O     . THR A 1 224 ? 123.961 161.499 106.434 1.00 28.74  ?  224 THR B O     1 
ATOM 1719 C CB    . THR A 1 224 ? 123.807 161.333 103.602 1.00 28.74  ?  224 THR B CB    1 
ATOM 1720 O OG1   . THR A 1 224 ? 122.511 160.798 103.897 1.00 28.74  ?  224 THR B OG1   1 
ATOM 1721 C CG2   . THR A 1 224 ? 124.076 161.208 102.110 1.00 28.74  ?  224 THR B CG2   1 
ATOM 1722 N N     . VAL A 1 225 ? 126.181 161.144 106.355 1.00 24.96  ?  225 VAL B N     1 
ATOM 1723 C CA    . VAL A 1 225 ? 126.442 161.797 107.631 1.00 24.96  ?  225 VAL B CA    1 
ATOM 1724 C C     . VAL A 1 225 ? 126.401 163.305 107.428 1.00 24.96  ?  225 VAL B C     1 
ATOM 1725 O O     . VAL A 1 225 ? 126.810 163.823 106.385 1.00 24.96  ?  225 VAL B O     1 
ATOM 1726 C CB    . VAL A 1 225 ? 127.792 161.335 108.210 1.00 24.96  ?  225 VAL B CB    1 
ATOM 1727 C CG1   . VAL A 1 225 ? 128.050 161.991 109.544 1.00 24.96  ?  225 VAL B CG1   1 
ATOM 1728 C CG2   . VAL A 1 225 ? 127.804 159.831 108.360 1.00 24.96  ?  225 VAL B CG2   1 
ATOM 1729 N N     . THR A 1 226 ? 125.898 164.019 108.429 1.00 26.21  ?  226 THR B N     1 
ATOM 1730 C CA    . THR A 1 226 ? 125.657 165.455 108.333 1.00 26.21  ?  226 THR B CA    1 
ATOM 1731 C C     . THR A 1 226 ? 126.300 166.185 109.504 1.00 26.21  ?  226 THR B C     1 
ATOM 1732 O O     . THR A 1 226 ? 125.651 166.940 110.231 1.00 26.21  ?  226 THR B O     1 
ATOM 1733 C CB    . THR A 1 226 ? 124.163 165.751 108.255 1.00 26.21  ?  226 THR B CB    1 
ATOM 1734 O OG1   . THR A 1 226 ? 123.524 164.750 107.453 1.00 26.21  ?  226 THR B OG1   1 
ATOM 1735 C CG2   . THR A 1 226 ? 123.924 167.111 107.617 1.00 26.21  ?  226 THR B CG2   1 
ATOM 1736 N N     . LEU A 1 227 ? 127.589 165.926 109.723 1.00 27.88  ?  227 LEU B N     1 
ATOM 1737 C CA    . LEU A 1 227 ? 128.358 166.617 110.752 1.00 27.88  ?  227 LEU B CA    1 
ATOM 1738 C C     . LEU A 1 227 ? 128.121 168.118 110.708 1.00 27.88  ?  227 LEU B C     1 
ATOM 1739 O O     . LEU A 1 227 ? 128.379 168.770 109.692 1.00 27.88  ?  227 LEU B O     1 
ATOM 1740 C CB    . LEU A 1 227 ? 129.849 166.324 110.577 1.00 27.88  ?  227 LEU B CB    1 
ATOM 1741 C CG    . LEU A 1 227 ? 130.549 165.482 111.641 1.00 27.88  ?  227 LEU B CG    1 
ATOM 1742 C CD1   . LEU A 1 227 ? 129.986 164.083 111.671 1.00 27.88  ?  227 LEU B CD1   1 
ATOM 1743 C CD2   . LEU A 1 227 ? 132.041 165.449 111.385 1.00 27.88  ?  227 LEU B CD2   1 
ATOM 1744 N N     . SER A 1 228 ? 127.624 168.661 111.816 1.00 37.26  ?  228 SER B N     1 
ATOM 1745 C CA    . SER A 1 228 ? 127.401 170.093 111.964 1.00 37.26  ?  228 SER B CA    1 
ATOM 1746 C C     . SER A 1 228 ? 128.103 170.553 113.229 1.00 37.26  ?  228 SER B C     1 
ATOM 1747 O O     . SER A 1 228 ? 127.837 170.028 114.315 1.00 37.26  ?  228 SER B O     1 
ATOM 1748 C CB    . SER A 1 228 ? 125.907 170.417 112.026 1.00 37.26  ?  228 SER B CB    1 
ATOM 1749 O OG    . SER A 1 228 ? 125.220 169.845 110.927 1.00 37.26  ?  228 SER B OG    1 
ATOM 1750 N N     . MET A 1 229 ? 128.998 171.528 113.092 1.00 48.70  ?  229 MET B N     1 
ATOM 1751 C CA    . MET A 1 229 ? 129.794 172.000 114.212 1.00 48.70  ?  229 MET B CA    1 
ATOM 1752 C C     . MET A 1 229 ? 129.928 173.513 114.154 1.00 48.70  ?  229 MET B C     1 
ATOM 1753 O O     . MET A 1 229 ? 129.811 174.133 113.094 1.00 48.70  ?  229 MET B O     1 
ATOM 1754 C CB    . MET A 1 229 ? 131.181 171.343 114.235 1.00 48.70  ?  229 MET B CB    1 
ATOM 1755 C CG    . MET A 1 229 ? 132.191 171.974 113.292 1.00 48.70  ?  229 MET B CG    1 
ATOM 1756 S SD    . MET A 1 229 ? 133.309 170.752 112.584 1.00 48.70  ?  229 MET B SD    1 
ATOM 1757 C CE    . MET A 1 229 ? 132.390 170.225 111.145 1.00 48.70  ?  229 MET B CE    1 
ATOM 1758 N N     . SER A 1 230 ? 130.175 174.100 115.322 1.00 56.85  ?  230 SER B N     1 
ATOM 1759 C CA    . SER A 1 230 ? 130.379 175.534 115.454 1.00 56.85  ?  230 SER B CA    1 
ATOM 1760 C C     . SER A 1 230 ? 131.234 175.784 116.689 1.00 56.85  ?  230 SER B C     1 
ATOM 1761 O O     . SER A 1 230 ? 131.570 174.859 117.434 1.00 56.85  ?  230 SER B O     1 
ATOM 1762 C CB    . SER A 1 230 ? 129.046 176.281 115.538 1.00 56.85  ?  230 SER B CB    1 
ATOM 1763 O OG    . SER A 1 230 ? 129.241 177.611 115.985 1.00 56.85  ?  230 SER B OG    1 
ATOM 1764 N N     . ALA A 1 231 ? 131.586 177.050 116.901 1.00 66.10  ?  231 ALA B N     1 
ATOM 1765 C CA    . ALA A 1 231 ? 132.432 177.412 118.030 1.00 66.10  ?  231 ALA B CA    1 
ATOM 1766 C C     . ALA A 1 231 ? 131.733 177.104 119.348 1.00 66.10  ?  231 ALA B C     1 
ATOM 1767 O O     . ALA A 1 231 ? 130.516 177.265 119.474 1.00 66.10  ?  231 ALA B O     1 
ATOM 1768 C CB    . ALA A 1 231 ? 132.801 178.893 117.959 1.00 66.10  ?  231 ALA B CB    1 
ATOM 1769 N N     . ASP A 1 232 ? 132.525 176.647 120.329 1.00 68.07  ?  232 ASP B N     1 
ATOM 1770 C CA    . ASP A 1 232 ? 132.124 176.272 121.690 1.00 68.07  ?  232 ASP B CA    1 
ATOM 1771 C C     . ASP A 1 232 ? 130.704 175.716 121.745 1.00 68.07  ?  232 ASP B C     1 
ATOM 1772 O O     . ASP A 1 232 ? 129.894 176.145 122.573 1.00 68.07  ?  232 ASP B O     1 
ATOM 1773 C CB    . ASP A 1 232 ? 132.300 177.398 122.741 1.00 68.07  ?  232 ASP B CB    1 
ATOM 1774 C CG    . ASP A 1 232 ? 132.009 178.816 122.236 1.00 68.07  ?  232 ASP B CG    1 
ATOM 1775 O OD1   . ASP A 1 232 ? 132.104 179.741 123.070 1.00 68.07  ?  232 ASP B OD1   1 
ATOM 1776 O OD2   . ASP A 1 232 ? 131.684 179.052 121.067 1.00 68.07  -1 232 ASP B OD2   1 
ATOM 1777 N N     . VAL A 1 233 ? 130.399 174.763 120.871 1.00 60.46  ?  233 VAL B N     1 
ATOM 1778 C CA    . VAL A 1 233 ? 129.078 174.142 120.817 1.00 60.46  ?  233 VAL B CA    1 
ATOM 1779 C C     . VAL A 1 233 ? 129.270 172.654 120.548 1.00 60.46  ?  233 VAL B C     1 
ATOM 1780 O O     . VAL A 1 233 ? 130.135 172.283 119.742 1.00 60.46  ?  233 VAL B O     1 
ATOM 1781 C CB    . VAL A 1 233 ? 128.195 174.813 119.751 1.00 60.46  ?  233 VAL B CB    1 
ATOM 1782 C CG1   . VAL A 1 233 ? 127.150 173.846 119.213 1.00 60.46  ?  233 VAL B CG1   1 
ATOM 1783 C CG2   . VAL A 1 233 ? 127.532 176.056 120.322 1.00 60.46  ?  233 VAL B CG2   1 
ATOM 1784 N N     . PRO A 1 234 ? 128.516 171.772 121.205 1.00 51.30  ?  234 PRO B N     1 
ATOM 1785 C CA    . PRO A 1 234 ? 128.701 170.334 120.978 1.00 51.30  ?  234 PRO B CA    1 
ATOM 1786 C C     . PRO A 1 234 ? 128.472 169.953 119.522 1.00 51.30  ?  234 PRO B C     1 
ATOM 1787 O O     . PRO A 1 234 ? 127.601 170.501 118.845 1.00 51.30  ?  234 PRO B O     1 
ATOM 1788 C CB    . PRO A 1 234 ? 127.658 169.692 121.899 1.00 51.30  ?  234 PRO B CB    1 
ATOM 1789 C CG    . PRO A 1 234 ? 127.409 170.712 122.956 1.00 51.30  ?  234 PRO B CG    1 
ATOM 1790 C CD    . PRO A 1 234 ? 127.549 172.044 122.282 1.00 51.30  ?  234 PRO B CD    1 
ATOM 1791 N N     . LEU A 1 235 ? 129.277 169.008 119.045 1.00 37.74  ?  235 LEU B N     1 
ATOM 1792 C CA    . LEU A 1 235 ? 129.152 168.529 117.676 1.00 37.74  ?  235 LEU B CA    1 
ATOM 1793 C C     . LEU A 1 235 ? 127.891 167.690 117.519 1.00 37.74  ?  235 LEU B C     1 
ATOM 1794 O O     . LEU A 1 235 ? 127.490 166.964 118.432 1.00 37.74  ?  235 LEU B O     1 
ATOM 1795 C CB    . LEU A 1 235 ? 130.384 167.710 117.291 1.00 37.74  ?  235 LEU B CB    1 
ATOM 1796 C CG    . LEU A 1 235 ? 130.334 166.892 116.000 1.00 37.74  ?  235 LEU B CG    1 
ATOM 1797 C CD1   . LEU A 1 235 ? 130.663 167.761 114.801 1.00 37.74  ?  235 LEU B CD1   1 
ATOM 1798 C CD2   . LEU A 1 235 ? 131.278 165.706 116.079 1.00 37.74  ?  235 LEU B CD2   1 
ATOM 1799 N N     . VAL A 1 236 ? 127.263 167.792 116.351 1.00 32.19  ?  236 VAL B N     1 
ATOM 1800 C CA    . VAL A 1 236 ? 126.037 167.067 116.042 1.00 32.19  ?  236 VAL B CA    1 
ATOM 1801 C C     . VAL A 1 236 ? 126.326 166.120 114.887 1.00 32.19  ?  236 VAL B C     1 
ATOM 1802 O O     . VAL A 1 236 ? 126.734 166.559 113.805 1.00 32.19  ?  236 VAL B O     1 
ATOM 1803 C CB    . VAL A 1 236 ? 124.885 168.021 115.694 1.00 32.19  ?  236 VAL B CB    1 
ATOM 1804 C CG1   . VAL A 1 236 ? 123.823 167.302 114.883 1.00 32.19  ?  236 VAL B CG1   1 
ATOM 1805 C CG2   . VAL A 1 236 ? 124.288 168.608 116.959 1.00 32.19  ?  236 VAL B CG2   1 
ATOM 1806 N N     . VAL A 1 237 ? 126.118 164.827 115.117 1.00 27.79  ?  237 VAL B N     1 
ATOM 1807 C CA    . VAL A 1 237 ? 126.246 163.800 114.090 1.00 27.79  ?  237 VAL B CA    1 
ATOM 1808 C C     . VAL A 1 237 ? 124.862 163.213 113.861 1.00 27.79  ?  237 VAL B C     1 
ATOM 1809 O O     . VAL A 1 237 ? 124.292 162.586 114.762 1.00 27.79  ?  237 VAL B O     1 
ATOM 1810 C CB    . VAL A 1 237 ? 127.246 162.709 114.500 1.00 27.79  ?  237 VAL B CB    1 
ATOM 1811 C CG1   . VAL A 1 237 ? 127.621 161.859 113.305 1.00 27.79  ?  237 VAL B CG1   1 
ATOM 1812 C CG2   . VAL A 1 237 ? 128.479 163.331 115.122 1.00 27.79  ?  237 VAL B CG2   1 
ATOM 1813 N N     . GLU A 1 238 ? 124.321 163.408 112.663 1.00 32.38  ?  238 GLU B N     1 
ATOM 1814 C CA    . GLU A 1 238 ? 122.935 163.072 112.372 1.00 32.38  ?  238 GLU B CA    1 
ATOM 1815 C C     . GLU A 1 238 ? 122.861 162.096 111.209 1.00 32.38  ?  238 GLU B C     1 
ATOM 1816 O O     . GLU A 1 238 ? 123.542 162.278 110.196 1.00 32.38  ?  238 GLU B O     1 
ATOM 1817 C CB    . GLU A 1 238 ? 122.128 164.332 112.054 1.00 32.38  ?  238 GLU B CB    1 
ATOM 1818 C CG    . GLU A 1 238 ? 121.016 164.124 111.045 1.00 32.38  ?  238 GLU B CG    1 
ATOM 1819 C CD    . GLU A 1 238 ? 120.122 165.337 110.912 1.00 32.38  ?  238 GLU B CD    1 
ATOM 1820 O OE1   . GLU A 1 238 ? 120.241 166.256 111.748 1.00 32.38  ?  238 GLU B OE1   1 
ATOM 1821 O OE2   . GLU A 1 238 ? 119.300 165.372 109.972 1.00 32.38  -1 238 GLU B OE2   1 
ATOM 1822 N N     . TYR A 1 239 ? 122.033 161.067 111.360 1.00 21.95  ?  239 TYR B N     1 
ATOM 1823 C CA    . TYR A 1 239 ? 121.705 160.142 110.288 1.00 21.95  ?  239 TYR B CA    1 
ATOM 1824 C C     . TYR A 1 239 ? 120.207 160.197 110.027 1.00 21.95  ?  239 TYR B C     1 
ATOM 1825 O O     . TYR A 1 239 ? 119.424 160.565 110.906 1.00 21.95  ?  239 TYR B O     1 
ATOM 1826 C CB    . TYR A 1 239 ? 122.108 158.701 110.624 1.00 21.95  ?  239 TYR B CB    1 
ATOM 1827 C CG    . TYR A 1 239 ? 123.565 158.504 110.965 1.00 21.95  ?  239 TYR B CG    1 
ATOM 1828 C CD1   . TYR A 1 239 ? 124.097 158.986 112.150 1.00 21.95  ?  239 TYR B CD1   1 
ATOM 1829 C CD2   . TYR A 1 239 ? 124.408 157.823 110.102 1.00 21.95  ?  239 TYR B CD2   1 
ATOM 1830 C CE1   . TYR A 1 239 ? 125.423 158.801 112.461 1.00 21.95  ?  239 TYR B CE1   1 
ATOM 1831 C CE2   . TYR A 1 239 ? 125.735 157.633 110.405 1.00 21.95  ?  239 TYR B CE2   1 
ATOM 1832 C CZ    . TYR A 1 239 ? 126.238 158.124 111.585 1.00 21.95  ?  239 TYR B CZ    1 
ATOM 1833 O OH    . TYR A 1 239 ? 127.565 157.937 111.890 1.00 21.95  ?  239 TYR B OH    1 
ATOM 1834 N N     . LYS A 1 240 ? 119.811 159.831 108.815 1.00 34.89  ?  240 LYS B N     1 
ATOM 1835 C CA    . LYS A 1 240 ? 118.406 159.811 108.431 1.00 34.89  ?  240 LYS B CA    1 
ATOM 1836 C C     . LYS A 1 240 ? 117.918 158.369 108.403 1.00 34.89  ?  240 LYS B C     1 
ATOM 1837 O O     . LYS A 1 240 ? 118.477 157.535 107.684 1.00 34.89  ?  240 LYS B O     1 
ATOM 1838 C CB    . LYS A 1 240 ? 118.201 160.477 107.072 1.00 34.89  ?  240 LYS B CB    1 
ATOM 1839 C CG    . LYS A 1 240 ? 118.276 161.991 107.113 1.00 34.89  ?  240 LYS B CG    1 
ATOM 1840 C CD    . LYS A 1 240 ? 117.240 162.568 108.063 1.00 34.89  ?  240 LYS B CD    1 
ATOM 1841 C CE    . LYS A 1 240 ? 115.828 162.265 107.592 1.00 34.89  ?  240 LYS B CE    1 
ATOM 1842 N NZ    . LYS A 1 240 ? 115.663 162.521 106.136 1.00 34.89  1  240 LYS B NZ    1 
ATOM 1843 N N     . ILE A 1 241 ? 116.878 158.081 109.178 1.00 41.74  ?  241 ILE B N     1 
ATOM 1844 C CA    . ILE A 1 241 ? 116.332 156.717 109.260 1.00 41.74  ?  241 ILE B CA    1 
ATOM 1845 C C     . ILE A 1 241 ? 115.287 156.616 108.154 1.00 41.74  ?  241 ILE B C     1 
ATOM 1846 O O     . ILE A 1 241 ? 114.084 156.787 108.362 1.00 41.74  ?  241 ILE B O     1 
ATOM 1847 C CB    . ILE A 1 241 ? 115.761 156.406 110.644 1.00 41.74  ?  241 ILE B CB    1 
ATOM 1848 C CG1   . ILE A 1 241 ? 116.803 156.684 111.722 1.00 41.74  ?  241 ILE B CG1   1 
ATOM 1849 C CG2   . ILE A 1 241 ? 115.322 154.961 110.719 1.00 41.74  ?  241 ILE B CG2   1 
ATOM 1850 C CD1   . ILE A 1 241 ? 118.037 155.842 111.583 1.00 41.74  ?  241 ILE B CD1   1 
ATOM 1851 N N     . ALA A 1 242 ? 115.765 156.315 106.945 1.00 46.75  ?  242 ALA B N     1 
ATOM 1852 C CA    . ALA A 1 242 ? 114.915 156.215 105.764 1.00 46.75  ?  242 ALA B CA    1 
ATOM 1853 C C     . ALA A 1 242 ? 114.028 157.446 105.630 1.00 46.75  ?  242 ALA B C     1 
ATOM 1854 O O     . ALA A 1 242 ? 114.519 158.550 105.378 1.00 46.75  ?  242 ALA B O     1 
ATOM 1855 C CB    . ALA A 1 242 ? 114.062 154.946 105.816 1.00 46.75  ?  242 ALA B CB    1 
ATOM 1856 N N     . ASP A 1 243 ? 112.723 157.263 105.800 1.00 55.59  ?  243 ASP B N     1 
ATOM 1857 C CA    . ASP A 1 243 ? 111.764 158.359 105.871 1.00 55.59  ?  243 ASP B CA    1 
ATOM 1858 C C     . ASP A 1 243 ? 110.929 158.178 107.140 1.00 55.59  ?  243 ASP B C     1 
ATOM 1859 O O     . ASP A 1 243 ? 109.697 158.152 107.130 1.00 55.59  ?  243 ASP B O     1 
ATOM 1860 C CB    . ASP A 1 243 ? 110.934 158.403 104.583 1.00 55.59  ?  243 ASP B CB    1 
ATOM 1861 C CG    . ASP A 1 243 ? 109.800 159.431 104.615 1.00 55.59  ?  243 ASP B CG    1 
ATOM 1862 O OD1   . ASP A 1 243 ? 109.097 159.551 103.590 1.00 55.59  ?  243 ASP B OD1   1 
ATOM 1863 O OD2   . ASP A 1 243 ? 109.655 160.182 105.602 1.00 55.59  -1 243 ASP B OD2   1 
ATOM 1864 N N     . MET A 1 244 ? 111.618 157.967 108.256 1.00 46.59  ?  244 MET B N     1 
ATOM 1865 C CA    . MET A 1 244 ? 110.974 157.722 109.537 1.00 46.59  ?  244 MET B CA    1 
ATOM 1866 C C     . MET A 1 244 ? 111.428 158.659 110.642 1.00 46.59  ?  244 MET B C     1 
ATOM 1867 O O     . MET A 1 244 ? 110.627 158.984 111.520 1.00 46.59  ?  244 MET B O     1 
ATOM 1868 C CB    . MET A 1 244 ? 111.222 156.275 109.989 1.00 46.59  ?  244 MET B CB    1 
ATOM 1869 C CG    . MET A 1 244 ? 110.185 155.296 109.486 1.00 46.59  ?  244 MET B CG    1 
ATOM 1870 S SD    . MET A 1 244 ? 110.019 153.835 110.525 1.00 46.59  ?  244 MET B SD    1 
ATOM 1871 C CE    . MET A 1 244 ? 111.720 153.297 110.621 1.00 46.59  ?  244 MET B CE    1 
ATOM 1872 N N     . GLY A 1 245 ? 112.681 159.098 110.626 1.00 40.97  ?  245 GLY B N     1 
ATOM 1873 C CA    . GLY A 1 245 ? 113.173 159.973 111.672 1.00 40.97  ?  245 GLY B CA    1 
ATOM 1874 C C     . GLY A 1 245 ? 114.663 160.191 111.522 1.00 40.97  ?  245 GLY B C     1 
ATOM 1875 O O     . GLY A 1 245 ? 115.229 159.979 110.448 1.00 40.97  ?  245 GLY B O     1 
ATOM 1876 N N     . HIS A 1 246 ? 115.287 160.615 112.617 1.00 39.20  ?  246 HIS B N     1 
ATOM 1877 C CA    . HIS A 1 246 ? 116.711 160.900 112.628 1.00 39.20  ?  246 HIS B CA    1 
ATOM 1878 C C     . HIS A 1 246 ? 117.308 160.441 113.947 1.00 39.20  ?  246 HIS B C     1 
ATOM 1879 O O     . HIS A 1 246 ? 116.634 160.424 114.978 1.00 39.20  ?  246 HIS B O     1 
ATOM 1880 C CB    . HIS A 1 246 ? 116.983 162.391 112.426 1.00 39.20  ?  246 HIS B CB    1 
ATOM 1881 C CG    . HIS A 1 246 ? 116.188 163.273 113.334 1.00 39.20  ?  246 HIS B CG    1 
ATOM 1882 N ND1   . HIS A 1 246 ? 116.562 163.532 114.634 1.00 39.20  ?  246 HIS B ND1   1 
ATOM 1883 C CD2   . HIS A 1 246 ? 115.035 163.953 113.132 1.00 39.20  ?  246 HIS B CD2   1 
ATOM 1884 C CE1   . HIS A 1 246 ? 115.676 164.336 115.193 1.00 39.20  ?  246 HIS B CE1   1 
ATOM 1885 N NE2   . HIS A 1 246 ? 114.739 164.606 114.303 1.00 39.20  ?  246 HIS B NE2   1 
ATOM 1886 N N     . LEU A 1 247 ? 118.584 160.076 113.904 1.00 54.26  ?  247 LEU B N     1 
ATOM 1887 C CA    . LEU A 1 247 ? 119.321 159.622 115.079 1.00 54.26  ?  247 LEU B CA    1 
ATOM 1888 C C     . LEU A 1 247 ? 120.519 160.548 115.255 1.00 54.26  ?  247 LEU B C     1 
ATOM 1889 O O     . LEU A 1 247 ? 121.542 160.384 114.585 1.00 54.26  ?  247 LEU B O     1 
ATOM 1890 C CB    . LEU A 1 247 ? 119.749 158.168 114.922 1.00 54.26  ?  247 LEU B CB    1 
ATOM 1891 C CG    . LEU A 1 247 ? 120.701 157.614 115.978 1.00 54.26  ?  247 LEU B CG    1 
ATOM 1892 C CD1   . LEU A 1 247 ? 119.989 157.443 117.301 1.00 54.26  ?  247 LEU B CD1   1 
ATOM 1893 C CD2   . LEU A 1 247 ? 121.290 156.297 115.519 1.00 54.26  ?  247 LEU B CD2   1 
ATOM 1894 N N     . LYS A 1 248 ? 120.394 161.518 116.154 1.00 28.00  ?  248 LYS B N     1 
ATOM 1895 C CA    . LYS A 1 248 ? 121.416 162.534 116.360 1.00 28.00  ?  248 LYS B CA    1 
ATOM 1896 C C     . LYS A 1 248 ? 122.292 162.176 117.551 1.00 28.00  ?  248 LYS B C     1 
ATOM 1897 O O     . LYS A 1 248 ? 121.796 161.725 118.586 1.00 28.00  ?  248 LYS B O     1 
ATOM 1898 C CB    . LYS A 1 248 ? 120.783 163.906 116.589 1.00 28.00  ?  248 LYS B CB    1 
ATOM 1899 C CG    . LYS A 1 248 ? 119.991 164.431 115.411 1.00 28.00  ?  248 LYS B CG    1 
ATOM 1900 C CD    . LYS A 1 248 ? 119.312 165.742 115.759 1.00 28.00  ?  248 LYS B CD    1 
ATOM 1901 C CE    . LYS A 1 248 ? 118.552 166.304 114.571 1.00 28.00  ?  248 LYS B CE    1 
ATOM 1902 N NZ    . LYS A 1 248 ? 117.837 167.561 114.920 1.00 28.00  1  248 LYS B NZ    1 
ATOM 1903 N N     . TYR A 1 249 ? 123.595 162.381 117.399 1.00 38.63  ?  249 TYR B N     1 
ATOM 1904 C CA    . TYR A 1 249 ? 124.550 162.207 118.483 1.00 38.63  ?  249 TYR B CA    1 
ATOM 1905 C C     . TYR A 1 249 ? 125.127 163.566 118.846 1.00 38.63  ?  249 TYR B C     1 
ATOM 1906 O O     . TYR A 1 249 ? 125.497 164.343 117.960 1.00 38.63  ?  249 TYR B O     1 
ATOM 1907 C CB    . TYR A 1 249 ? 125.684 161.257 118.096 1.00 38.63  ?  249 TYR B CB    1 
ATOM 1908 C CG    . TYR A 1 249 ? 125.274 159.824 117.864 1.00 38.63  ?  249 TYR B CG    1 
ATOM 1909 C CD1   . TYR A 1 249 ? 125.801 158.803 118.634 1.00 38.63  ?  249 TYR B CD1   1 
ATOM 1910 C CD2   . TYR A 1 249 ? 124.408 159.484 116.839 1.00 38.63  ?  249 TYR B CD2   1 
ATOM 1911 C CE1   . TYR A 1 249 ? 125.450 157.491 118.420 1.00 38.63  ?  249 TYR B CE1   1 
ATOM 1912 C CE2   . TYR A 1 249 ? 124.054 158.175 116.614 1.00 38.63  ?  249 TYR B CE2   1 
ATOM 1913 C CZ    . TYR A 1 249 ? 124.576 157.181 117.408 1.00 38.63  ?  249 TYR B CZ    1 
ATOM 1914 O OH    . TYR A 1 249 ? 124.223 155.871 117.187 1.00 38.63  ?  249 TYR B OH    1 
ATOM 1915 N N     . TYR A 1 250 ? 125.209 163.850 120.141 1.00 37.98  ?  250 TYR B N     1 
ATOM 1916 C CA    . TYR A 1 250 ? 125.741 165.110 120.635 1.00 37.98  ?  250 TYR B CA    1 
ATOM 1917 C C     . TYR A 1 250 ? 127.024 164.843 121.406 1.00 37.98  ?  250 TYR B C     1 
ATOM 1918 O O     . TYR A 1 250 ? 127.051 163.985 122.294 1.00 37.98  ?  250 TYR B O     1 
ATOM 1919 C CB    . TYR A 1 250 ? 124.725 165.825 121.526 1.00 37.98  ?  250 TYR B CB    1 
ATOM 1920 C CG    . TYR A 1 250 ? 123.591 166.478 120.771 1.00 37.98  ?  250 TYR B CG    1 
ATOM 1921 C CD1   . TYR A 1 250 ? 122.681 165.718 120.051 1.00 37.98  ?  250 TYR B CD1   1 
ATOM 1922 C CD2   . TYR A 1 250 ? 123.428 167.854 120.782 1.00 37.98  ?  250 TYR B CD2   1 
ATOM 1923 C CE1   . TYR A 1 250 ? 121.644 166.310 119.363 1.00 37.98  ?  250 TYR B CE1   1 
ATOM 1924 C CE2   . TYR A 1 250 ? 122.395 168.454 120.096 1.00 37.98  ?  250 TYR B CE2   1 
ATOM 1925 C CZ    . TYR A 1 250 ? 121.506 167.678 119.389 1.00 37.98  ?  250 TYR B CZ    1 
ATOM 1926 O OH    . TYR A 1 250 ? 120.474 168.273 118.704 1.00 37.98  ?  250 TYR B OH    1 
ATOM 1927 N N     . LEU A 1 251 ? 128.083 165.573 121.065 1.00 41.94  ?  251 LEU B N     1 
ATOM 1928 C CA    . LEU A 1 251 ? 129.377 165.415 121.718 1.00 41.94  ?  251 LEU B CA    1 
ATOM 1929 C C     . LEU A 1 251 ? 130.003 166.786 121.905 1.00 41.94  ?  251 LEU B C     1 
ATOM 1930 O O     . LEU A 1 251 ? 130.224 167.506 120.928 1.00 41.94  ?  251 LEU B O     1 
ATOM 1931 C CB    . LEU A 1 251 ? 130.303 164.512 120.901 1.00 41.94  ?  251 LEU B CB    1 
ATOM 1932 C CG    . LEU A 1 251 ? 131.687 164.273 121.497 1.00 41.94  ?  251 LEU B CG    1 
ATOM 1933 C CD1   . LEU A 1 251 ? 131.566 163.661 122.879 1.00 41.94  ?  251 LEU B CD1   1 
ATOM 1934 C CD2   . LEU A 1 251 ? 132.509 163.383 120.588 1.00 41.94  ?  251 LEU B CD2   1 
ATOM 1935 N N     . ALA A 1 252 ? 130.285 167.141 123.154 1.00 48.21  ?  252 ALA B N     1 
ATOM 1936 C CA    . ALA A 1 252 ? 130.909 168.424 123.438 1.00 48.21  ?  252 ALA B CA    1 
ATOM 1937 C C     . ALA A 1 252 ? 132.374 168.403 123.009 1.00 48.21  ?  252 ALA B C     1 
ATOM 1938 O O     . ALA A 1 252 ? 133.087 167.431 123.277 1.00 48.21  ?  252 ALA B O     1 
ATOM 1939 C CB    . ALA A 1 252 ? 130.805 168.755 124.925 1.00 48.21  ?  252 ALA B CB    1 
ATOM 1940 N N     . PRO A 1 253 ? 132.851 169.453 122.342 1.00 51.10  ?  253 PRO B N     1 
ATOM 1941 C CA    . PRO A 1 253 ? 134.253 169.476 121.918 1.00 51.10  ?  253 PRO B CA    1 
ATOM 1942 C C     . PRO A 1 253 ? 135.188 169.499 123.115 1.00 51.10  ?  253 PRO B C     1 
ATOM 1943 O O     . PRO A 1 253 ? 134.882 170.073 124.161 1.00 51.10  ?  253 PRO B O     1 
ATOM 1944 C CB    . PRO A 1 253 ? 134.356 170.769 121.103 1.00 51.10  ?  253 PRO B CB    1 
ATOM 1945 C CG    . PRO A 1 253 ? 133.277 171.634 121.644 1.00 51.10  ?  253 PRO B CG    1 
ATOM 1946 C CD    . PRO A 1 253 ? 132.156 170.711 122.026 1.00 51.10  ?  253 PRO B CD    1 
ATOM 1947 N N     . LYS A 1 254 ? 136.342 168.862 122.949 1.00 64.59  ?  254 LYS B N     1 
ATOM 1948 C CA    . LYS A 1 254 ? 137.329 168.832 124.014 1.00 64.59  ?  254 LYS B CA    1 
ATOM 1949 C C     . LYS A 1 254 ? 137.979 170.201 124.180 1.00 64.59  ?  254 LYS B C     1 
ATOM 1950 O O     . LYS A 1 254 ? 138.004 171.027 123.263 1.00 64.59  ?  254 LYS B O     1 
ATOM 1951 C CB    . LYS A 1 254 ? 138.392 167.772 123.731 1.00 64.59  ?  254 LYS B CB    1 
ATOM 1952 C CG    . LYS A 1 254 ? 137.856 166.356 123.767 1.00 64.59  ?  254 LYS B CG    1 
ATOM 1953 C CD    . LYS A 1 254 ? 137.204 166.058 125.104 1.00 64.59  ?  254 LYS B CD    1 
ATOM 1954 C CE    . LYS A 1 254 ? 135.892 165.317 124.922 1.00 64.59  ?  254 LYS B CE    1 
ATOM 1955 N NZ    . LYS A 1 254 ? 134.803 166.241 124.500 1.00 64.59  1  254 LYS B NZ    1 
ATOM 1956 N N     . ILE A 1 255 ? 138.506 170.435 125.375 1.00 115.36 ?  255 ILE B N     1 
ATOM 1957 C CA    . ILE A 1 255 ? 139.170 171.690 125.703 1.00 115.36 ?  255 ILE B CA    1 
ATOM 1958 C C     . ILE A 1 255 ? 140.648 171.560 125.363 1.00 115.36 ?  255 ILE B C     1 
ATOM 1959 O O     . ILE A 1 255 ? 141.303 170.590 125.762 1.00 115.36 ?  255 ILE B O     1 
ATOM 1960 C CB    . ILE A 1 255 ? 138.973 172.046 127.185 1.00 115.36 ?  255 ILE B CB    1 
ATOM 1961 C CG1   . ILE A 1 255 ? 137.498 171.914 127.569 1.00 115.36 ?  255 ILE B CG1   1 
ATOM 1962 C CG2   . ILE A 1 255 ? 139.476 173.452 127.466 1.00 115.36 ?  255 ILE B CG2   1 
ATOM 1963 C CD1   . ILE A 1 255 ? 137.239 172.053 129.052 1.00 115.36 ?  255 ILE B CD1   1 
ATOM 1964 N N     . GLU A 1 256 ? 141.172 172.534 124.615 1.00 145.44 ?  256 GLU B N     1 
ATOM 1965 C CA    . GLU A 1 256 ? 142.574 172.484 124.217 1.00 145.44 ?  256 GLU B CA    1 
ATOM 1966 C C     . GLU A 1 256 ? 143.506 172.557 125.419 1.00 145.44 ?  256 GLU B C     1 
ATOM 1967 O O     . GLU A 1 256 ? 144.630 172.044 125.364 1.00 145.44 ?  256 GLU B O     1 
ATOM 1968 C CB    . GLU A 1 256 ? 142.882 173.614 123.235 1.00 145.44 ?  256 GLU B CB    1 
ATOM 1969 C CG    . GLU A 1 256 ? 142.850 173.189 121.777 1.00 145.44 ?  256 GLU B CG    1 
ATOM 1970 C CD    . GLU A 1 256 ? 143.103 174.342 120.827 1.00 145.44 ?  256 GLU B CD    1 
ATOM 1971 O OE1   . GLU A 1 256 ? 143.203 175.493 121.301 1.00 145.44 ?  256 GLU B OE1   1 
ATOM 1972 O OE2   . GLU A 1 256 ? 143.203 174.097 119.607 1.00 145.44 -1 256 GLU B OE2   1 
ATOM 1973 N N     . ASP A 1 257 ? 143.063 173.187 126.510 1.00 154.73 ?  257 ASP B N     1 
ATOM 1974 C CA    . ASP A 1 257 ? 143.889 173.248 127.711 1.00 154.73 ?  257 ASP B CA    1 
ATOM 1975 C C     . ASP A 1 257 ? 144.065 171.873 128.343 1.00 154.73 ?  257 ASP B C     1 
ATOM 1976 O O     . ASP A 1 257 ? 145.034 171.649 129.077 1.00 154.73 ?  257 ASP B O     1 
ATOM 1977 C CB    . ASP A 1 257 ? 143.280 174.222 128.719 1.00 154.73 ?  257 ASP B CB    1 
ATOM 1978 C CG    . ASP A 1 257 ? 143.706 175.656 128.472 1.00 154.73 ?  257 ASP B CG    1 
ATOM 1979 O OD1   . ASP A 1 257 ? 144.657 175.869 127.691 1.00 154.73 ?  257 ASP B OD1   1 
ATOM 1980 O OD2   . ASP A 1 257 ? 143.090 176.570 129.059 1.00 154.73 -1 257 ASP B OD2   1 
ATOM 1981 N N     . GLU A 1 258 ? 143.140 170.947 128.077 1.00 145.90 ?  258 GLU B N     1 
ATOM 1982 C CA    . GLU A 1 258 ? 143.282 169.587 128.587 1.00 145.90 ?  258 GLU B CA    1 
ATOM 1983 C C     . GLU A 1 258 ? 144.508 168.904 127.996 1.00 145.90 ?  258 GLU B C     1 
ATOM 1984 O O     . GLU A 1 258 ? 145.238 168.198 128.703 1.00 145.90 ?  258 GLU B O     1 
ATOM 1985 C CB    . GLU A 1 258 ? 142.021 168.779 128.278 1.00 145.90 ?  258 GLU B CB    1 
ATOM 1986 C CG    . GLU A 1 258 ? 140.946 168.860 129.347 1.00 145.90 ?  258 GLU B CG    1 
ATOM 1987 C CD    . GLU A 1 258 ? 139.652 168.201 128.915 1.00 145.90 ?  258 GLU B CD    1 
ATOM 1988 O OE1   . GLU A 1 258 ? 139.558 167.788 127.740 1.00 145.90 ?  258 GLU B OE1   1 
ATOM 1989 O OE2   . GLU A 1 258 ? 138.728 168.096 129.749 1.00 145.90 -1 258 GLU B OE2   1 
ATOM 1990 N N     . GLU A 1 259 ? 144.751 169.102 126.699 1.00 145.16 ?  259 GLU B N     1 
ATOM 1991 C CA    . GLU A 1 259 ? 145.886 168.472 126.037 1.00 145.16 ?  259 GLU B CA    1 
ATOM 1992 C C     . GLU A 1 259 ? 147.215 169.107 126.424 1.00 145.16 ?  259 GLU B C     1 
ATOM 1993 O O     . GLU A 1 259 ? 148.267 168.519 126.155 1.00 145.16 ?  259 GLU B O     1 
ATOM 1994 C CB    . GLU A 1 259 ? 145.704 168.535 124.520 1.00 145.16 ?  259 GLU B CB    1 
ATOM 1995 C CG    . GLU A 1 259 ? 144.979 167.339 123.930 1.00 145.16 ?  259 GLU B CG    1 
ATOM 1996 C CD    . GLU A 1 259 ? 144.570 167.563 122.488 1.00 145.16 ?  259 GLU B CD    1 
ATOM 1997 O OE1   . GLU A 1 259 ? 144.678 168.712 122.010 1.00 145.16 ?  259 GLU B OE1   1 
ATOM 1998 O OE2   . GLU A 1 259 ? 144.143 166.592 121.832 1.00 145.16 -1 259 GLU B OE2   1 
ATOM 1999 N N     . GLY A 1 260 ? 147.191 170.291 127.039 1.00 144.70 ?  260 GLY B N     1 
ATOM 2000 C CA    . GLY A 1 260 ? 148.436 170.943 127.413 1.00 144.70 ?  260 GLY B CA    1 
ATOM 2001 C C     . GLY A 1 260 ? 149.215 170.170 128.460 1.00 144.70 ?  260 GLY B C     1 
ATOM 2002 O O     . GLY A 1 260 ? 150.437 170.035 128.364 1.00 144.70 ?  260 GLY B O     1 
ATOM 2003 N N     . SER A 1 261 ? 148.523 169.653 129.469 1.00 142.38 ?  261 SER B N     1 
ATOM 2004 C CA    . SER A 1 261 ? 149.172 168.896 130.532 1.00 142.38 ?  261 SER B CA    1 
ATOM 2005 C C     . SER A 1 261 ? 149.251 167.414 130.181 1.00 142.38 ?  261 SER B C     1 
ATOM 2006 O O     . SER A 1 261 ? 148.692 166.570 130.880 1.00 142.38 ?  261 SER B O     1 
ATOM 2007 C CB    . SER A 1 261 ? 148.428 169.083 131.856 1.00 142.38 ?  261 SER B CB    1 
ATOM 2008 O OG    . SER A 1 261 ? 147.202 168.373 131.856 1.00 142.38 ?  261 SER B OG    1 
ATOM 2009 N N     . MET B 1 1   ? 142.614 91.966  107.737 1.00 65.32  ?  1   MET C N     1 
ATOM 2010 C CA    . MET B 1 1   ? 143.174 93.274  107.423 1.00 65.32  ?  1   MET C CA    1 
ATOM 2011 C C     . MET B 1 1   ? 142.069 94.220  106.967 1.00 65.32  ?  1   MET C C     1 
ATOM 2012 O O     . MET B 1 1   ? 141.349 93.936  106.011 1.00 65.32  ?  1   MET C O     1 
ATOM 2013 C CB    . MET B 1 1   ? 144.258 93.149  106.351 1.00 65.32  ?  1   MET C CB    1 
ATOM 2014 C CG    . MET B 1 1   ? 144.412 94.365  105.452 1.00 65.32  ?  1   MET C CG    1 
ATOM 2015 S SD    . MET B 1 1   ? 146.071 94.493  104.761 1.00 65.32  ?  1   MET C SD    1 
ATOM 2016 C CE    . MET B 1 1   ? 146.047 96.165  104.124 1.00 65.32  ?  1   MET C CE    1 
ATOM 2017 N N     . PHE B 1 2   ? 141.934 95.343  107.666 1.00 49.75  ?  2   PHE C N     1 
ATOM 2018 C CA    . PHE B 1 2   ? 140.877 96.300  107.374 1.00 49.75  ?  2   PHE C CA    1 
ATOM 2019 C C     . PHE B 1 2   ? 141.299 97.217  106.235 1.00 49.75  ?  2   PHE C C     1 
ATOM 2020 O O     . PHE B 1 2   ? 142.401 97.774  106.251 1.00 49.75  ?  2   PHE C O     1 
ATOM 2021 C CB    . PHE B 1 2   ? 140.550 97.118  108.622 1.00 49.75  ?  2   PHE C CB    1 
ATOM 2022 C CG    . PHE B 1 2   ? 139.319 97.966  108.491 1.00 49.75  ?  2   PHE C CG    1 
ATOM 2023 C CD1   . PHE B 1 2   ? 138.322 97.635  107.594 1.00 49.75  ?  2   PHE C CD1   1 
ATOM 2024 C CD2   . PHE B 1 2   ? 139.160 99.097  109.272 1.00 49.75  ?  2   PHE C CD2   1 
ATOM 2025 C CE1   . PHE B 1 2   ? 137.191 98.417  107.476 1.00 49.75  ?  2   PHE C CE1   1 
ATOM 2026 C CE2   . PHE B 1 2   ? 138.032 99.882  109.159 1.00 49.75  ?  2   PHE C CE2   1 
ATOM 2027 C CZ    . PHE B 1 2   ? 137.047 99.542  108.260 1.00 49.75  ?  2   PHE C CZ    1 
ATOM 2028 N N     . GLU B 1 3   ? 140.423 97.371  105.245 1.00 46.31  ?  3   GLU C N     1 
ATOM 2029 C CA    . GLU B 1 3   ? 140.678 98.280  104.131 1.00 46.31  ?  3   GLU C CA    1 
ATOM 2030 C C     . GLU B 1 3   ? 139.340 98.810  103.640 1.00 46.31  ?  3   GLU C C     1 
ATOM 2031 O O     . GLU B 1 3   ? 138.531 98.049  103.102 1.00 46.31  ?  3   GLU C O     1 
ATOM 2032 C CB    . GLU B 1 3   ? 141.435 97.581  103.007 1.00 46.31  ?  3   GLU C CB    1 
ATOM 2033 C CG    . GLU B 1 3   ? 141.383 98.321  101.682 1.00 46.31  ?  3   GLU C CG    1 
ATOM 2034 C CD    . GLU B 1 3   ? 142.031 97.545  100.555 1.00 46.31  ?  3   GLU C CD    1 
ATOM 2035 O OE1   . GLU B 1 3   ? 142.497 96.414  100.801 1.00 46.31  ?  3   GLU C OE1   1 
ATOM 2036 O OE2   . GLU B 1 3   ? 142.070 98.067  99.421  1.00 46.31  -1 3   GLU C OE2   1 
ATOM 2037 N N     . ALA B 1 4   ? 139.107 100.106 103.831 1.00 38.08  ?  4   ALA C N     1 
ATOM 2038 C CA    . ALA B 1 4   ? 137.882 100.759 103.388 1.00 38.08  ?  4   ALA C CA    1 
ATOM 2039 C C     . ALA B 1 4   ? 138.255 101.973 102.554 1.00 38.08  ?  4   ALA C C     1 
ATOM 2040 O O     . ALA B 1 4   ? 139.009 102.834 103.016 1.00 38.08  ?  4   ALA C O     1 
ATOM 2041 C CB    . ALA B 1 4   ? 137.013 101.171 104.577 1.00 38.08  ?  4   ALA C CB    1 
ATOM 2042 N N     . ARG B 1 5   ? 137.729 102.042 101.336 1.00 39.28  ?  5   ARG C N     1 
ATOM 2043 C CA    . ARG B 1 5   ? 137.996 103.146 100.421 1.00 39.28  ?  5   ARG C CA    1 
ATOM 2044 C C     . ARG B 1 5   ? 136.715 103.954 100.263 1.00 39.28  ?  5   ARG C C     1 
ATOM 2045 O O     . ARG B 1 5   ? 135.745 103.480 99.664  1.00 39.28  ?  5   ARG C O     1 
ATOM 2046 C CB    . ARG B 1 5   ? 138.494 102.630 99.074  1.00 39.28  ?  5   ARG C CB    1 
ATOM 2047 C CG    . ARG B 1 5   ? 138.437 103.656 97.959  1.00 39.28  ?  5   ARG C CG    1 
ATOM 2048 C CD    . ARG B 1 5   ? 138.745 103.024 96.612  1.00 39.28  ?  5   ARG C CD    1 
ATOM 2049 N NE    . ARG B 1 5   ? 139.108 104.019 95.610  1.00 39.28  ?  5   ARG C NE    1 
ATOM 2050 C CZ    . ARG B 1 5   ? 140.262 104.671 95.583  1.00 39.28  ?  5   ARG C CZ    1 
ATOM 2051 N NH1   . ARG B 1 5   ? 141.205 104.447 96.484  1.00 39.28  1  5   ARG C NH1   1 
ATOM 2052 N NH2   . ARG B 1 5   ? 140.479 105.567 94.625  1.00 39.28  ?  5   ARG C NH2   1 
ATOM 2053 N N     . LEU B 1 6   ? 136.715 105.170 100.797 1.00 36.98  ?  6   LEU C N     1 
ATOM 2054 C CA    . LEU B 1 6   ? 135.559 106.054 100.762 1.00 36.98  ?  6   LEU C CA    1 
ATOM 2055 C C     . LEU B 1 6   ? 135.866 107.216 99.828  1.00 36.98  ?  6   LEU C C     1 
ATOM 2056 O O     . LEU B 1 6   ? 136.843 107.943 100.038 1.00 36.98  ?  6   LEU C O     1 
ATOM 2057 C CB    . LEU B 1 6   ? 135.219 106.555 102.164 1.00 36.98  ?  6   LEU C CB    1 
ATOM 2058 C CG    . LEU B 1 6   ? 134.246 107.725 102.275 1.00 36.98  ?  6   LEU C CG    1 
ATOM 2059 C CD1   . LEU B 1 6   ? 132.928 107.399 101.595 1.00 36.98  ?  6   LEU C CD1   1 
ATOM 2060 C CD2   . LEU B 1 6   ? 134.022 108.083 103.732 1.00 36.98  ?  6   LEU C CD2   1 
ATOM 2061 N N     . VAL B 1 7   ? 135.038 107.384 98.796  1.00 40.75  ?  7   VAL C N     1 
ATOM 2062 C CA    . VAL B 1 7   ? 135.324 108.388 97.775  1.00 40.75  ?  7   VAL C CA    1 
ATOM 2063 C C     . VAL B 1 7   ? 135.023 109.793 98.289  1.00 40.75  ?  7   VAL C C     1 
ATOM 2064 O O     . VAL B 1 7   ? 135.812 110.722 98.079  1.00 40.75  ?  7   VAL C O     1 
ATOM 2065 C CB    . VAL B 1 7   ? 134.550 108.068 96.485  1.00 40.75  ?  7   VAL C CB    1 
ATOM 2066 C CG1   . VAL B 1 7   ? 134.896 109.071 95.400  1.00 40.75  ?  7   VAL C CG1   1 
ATOM 2067 C CG2   . VAL B 1 7   ? 134.852 106.654 96.026  1.00 40.75  ?  7   VAL C CG2   1 
ATOM 2068 N N     . GLN B 1 8   ? 133.887 109.982 98.961  1.00 40.00  ?  8   GLN C N     1 
ATOM 2069 C CA    . GLN B 1 8   ? 133.531 111.290 99.515  1.00 40.00  ?  8   GLN C CA    1 
ATOM 2070 C C     . GLN B 1 8   ? 134.185 111.439 100.882 1.00 40.00  ?  8   GLN C C     1 
ATOM 2071 O O     . GLN B 1 8   ? 133.736 110.848 101.866 1.00 40.00  ?  8   GLN C O     1 
ATOM 2072 C CB    . GLN B 1 8   ? 132.018 111.470 99.626  1.00 40.00  ?  8   GLN C CB    1 
ATOM 2073 C CG    . GLN B 1 8   ? 131.222 111.738 98.336  1.00 40.00  ?  8   GLN C CG    1 
ATOM 2074 C CD    . GLN B 1 8   ? 131.431 110.735 97.214  1.00 40.00  ?  8   GLN C CD    1 
ATOM 2075 O OE1   . GLN B 1 8   ? 132.171 109.767 97.347  1.00 40.00  ?  8   GLN C OE1   1 
ATOM 2076 N NE2   . GLN B 1 8   ? 130.767 110.974 96.090  1.00 40.00  ?  8   GLN C NE2   1 
ATOM 2077 N N     . GLY B 1 9   ? 135.248 112.243 100.950 1.00 35.62  ?  9   GLY C N     1 
ATOM 2078 C CA    . GLY B 1 9   ? 135.841 112.563 102.235 1.00 35.62  ?  9   GLY C CA    1 
ATOM 2079 C C     . GLY B 1 9   ? 135.056 113.568 103.047 1.00 35.62  ?  9   GLY C C     1 
ATOM 2080 O O     . GLY B 1 9   ? 135.246 113.653 104.266 1.00 35.62  ?  9   GLY C O     1 
ATOM 2081 N N     . SER B 1 10  ? 134.173 114.327 102.395 1.00 36.17  ?  10  SER C N     1 
ATOM 2082 C CA    . SER B 1 10  ? 133.388 115.328 103.105 1.00 36.17  ?  10  SER C CA    1 
ATOM 2083 C C     . SER B 1 10  ? 132.477 114.691 104.143 1.00 36.17  ?  10  SER C C     1 
ATOM 2084 O O     . SER B 1 10  ? 132.245 115.279 105.204 1.00 36.17  ?  10  SER C O     1 
ATOM 2085 C CB    . SER B 1 10  ? 132.570 116.151 102.112 1.00 36.17  ?  10  SER C CB    1 
ATOM 2086 O OG    . SER B 1 10  ? 131.676 115.326 101.388 1.00 36.17  ?  10  SER C OG    1 
ATOM 2087 N N     . ILE B 1 11  ? 131.953 113.498 103.861 1.00 33.62  ?  11  ILE C N     1 
ATOM 2088 C CA    . ILE B 1 11  ? 131.082 112.824 104.821 1.00 33.62  ?  11  ILE C CA    1 
ATOM 2089 C C     . ILE B 1 11  ? 131.846 112.512 106.101 1.00 33.62  ?  11  ILE C C     1 
ATOM 2090 O O     . ILE B 1 11  ? 131.369 112.777 107.213 1.00 33.62  ?  11  ILE C O     1 
ATOM 2091 C CB    . ILE B 1 11  ? 130.481 111.554 104.196 1.00 33.62  ?  11  ILE C CB    1 
ATOM 2092 C CG1   . ILE B 1 11  ? 129.361 111.920 103.224 1.00 33.62  ?  11  ILE C CG1   1 
ATOM 2093 C CG2   . ILE B 1 11  ? 129.960 110.629 105.273 1.00 33.62  ?  11  ILE C CG2   1 
ATOM 2094 C CD1   . ILE B 1 11  ? 128.869 110.755 102.402 1.00 33.62  ?  11  ILE C CD1   1 
ATOM 2095 N N     . LEU B 1 12  ? 133.050 111.951 105.964 1.00 30.89  ?  12  LEU C N     1 
ATOM 2096 C CA    . LEU B 1 12  ? 133.860 111.651 107.139 1.00 30.89  ?  12  LEU C CA    1 
ATOM 2097 C C     . LEU B 1 12  ? 134.266 112.924 107.867 1.00 30.89  ?  12  LEU C C     1 
ATOM 2098 O O     . LEU B 1 12  ? 134.278 112.963 109.104 1.00 30.89  ?  12  LEU C O     1 
ATOM 2099 C CB    . LEU B 1 12  ? 135.093 110.844 106.738 1.00 30.89  ?  12  LEU C CB    1 
ATOM 2100 C CG    . LEU B 1 12  ? 135.096 109.394 107.215 1.00 30.89  ?  12  LEU C CG    1 
ATOM 2101 C CD1   . LEU B 1 12  ? 136.362 108.686 106.775 1.00 30.89  ?  12  LEU C CD1   1 
ATOM 2102 C CD2   . LEU B 1 12  ? 134.952 109.336 108.721 1.00 30.89  ?  12  LEU C CD2   1 
ATOM 2103 N N     . LYS B 1 13  ? 134.604 113.976 107.118 1.00 34.46  ?  13  LYS C N     1 
ATOM 2104 C CA    . LYS B 1 13  ? 134.951 115.244 107.751 1.00 34.46  ?  13  LYS C CA    1 
ATOM 2105 C C     . LYS B 1 13  ? 133.793 115.766 108.592 1.00 34.46  ?  13  LYS C C     1 
ATOM 2106 O O     . LYS B 1 13  ? 133.979 116.173 109.745 1.00 34.46  ?  13  LYS C O     1 
ATOM 2107 C CB    . LYS B 1 13  ? 135.348 116.268 106.689 1.00 34.46  ?  13  LYS C CB    1 
ATOM 2108 C CG    . LYS B 1 13  ? 136.724 116.046 106.091 1.00 34.46  ?  13  LYS C CG    1 
ATOM 2109 C CD    . LYS B 1 13  ? 137.033 117.079 105.022 1.00 34.46  ?  13  LYS C CD    1 
ATOM 2110 C CE    . LYS B 1 13  ? 137.085 118.480 105.604 1.00 34.46  ?  13  LYS C CE    1 
ATOM 2111 N NZ    . LYS B 1 13  ? 138.354 118.725 106.343 1.00 34.46  1  13  LYS C NZ    1 
ATOM 2112 N N     . LYS B 1 14  ? 132.582 115.743 108.032 1.00 32.18  ?  14  LYS C N     1 
ATOM 2113 C CA    . LYS B 1 14  ? 131.415 116.235 108.757 1.00 32.18  ?  14  LYS C CA    1 
ATOM 2114 C C     . LYS B 1 14  ? 131.116 115.376 109.978 1.00 32.18  ?  14  LYS C C     1 
ATOM 2115 O O     . LYS B 1 14  ? 130.777 115.901 111.044 1.00 32.18  ?  14  LYS C O     1 
ATOM 2116 C CB    . LYS B 1 14  ? 130.204 116.286 107.828 1.00 32.18  ?  14  LYS C CB    1 
ATOM 2117 C CG    . LYS B 1 14  ? 130.308 117.336 106.739 1.00 32.18  ?  14  LYS C CG    1 
ATOM 2118 C CD    . LYS B 1 14  ? 129.468 116.961 105.532 1.00 32.18  ?  14  LYS C CD    1 
ATOM 2119 C CE    . LYS B 1 14  ? 129.780 117.852 104.344 1.00 32.18  ?  14  LYS C CE    1 
ATOM 2120 N NZ    . LYS B 1 14  ? 129.081 117.395 103.112 1.00 32.18  1  14  LYS C NZ    1 
ATOM 2121 N N     . VAL B 1 15  ? 131.235 114.053 109.844 1.00 29.56  ?  15  VAL C N     1 
ATOM 2122 C CA    . VAL B 1 15  ? 130.965 113.169 110.976 1.00 29.56  ?  15  VAL C CA    1 
ATOM 2123 C C     . VAL B 1 15  ? 131.942 113.447 112.111 1.00 29.56  ?  15  VAL C C     1 
ATOM 2124 O O     . VAL B 1 15  ? 131.548 113.595 113.277 1.00 29.56  ?  15  VAL C O     1 
ATOM 2125 C CB    . VAL B 1 15  ? 131.022 111.697 110.531 1.00 29.56  ?  15  VAL C CB    1 
ATOM 2126 C CG1   . VAL B 1 15  ? 131.126 110.786 111.735 1.00 29.56  ?  15  VAL C CG1   1 
ATOM 2127 C CG2   . VAL B 1 15  ? 129.801 111.348 109.704 1.00 29.56  ?  15  VAL C CG2   1 
ATOM 2128 N N     . LEU B 1 16  ? 133.233 113.539 111.784 1.00 31.13  ?  16  LEU C N     1 
ATOM 2129 C CA    . LEU B 1 16  ? 134.234 113.787 112.816 1.00 31.13  ?  16  LEU C CA    1 
ATOM 2130 C C     . LEU B 1 16  ? 134.061 115.165 113.439 1.00 31.13  ?  16  LEU C C     1 
ATOM 2131 O O     . LEU B 1 16  ? 134.295 115.339 114.639 1.00 31.13  ?  16  LEU C O     1 
ATOM 2132 C CB    . LEU B 1 16  ? 135.639 113.624 112.243 1.00 31.13  ?  16  LEU C CB    1 
ATOM 2133 C CG    . LEU B 1 16  ? 136.254 112.226 112.321 1.00 31.13  ?  16  LEU C CG    1 
ATOM 2134 C CD1   . LEU B 1 16  ? 136.732 111.970 113.731 1.00 31.13  ?  16  LEU C CD1   1 
ATOM 2135 C CD2   . LEU B 1 16  ? 135.281 111.144 111.893 1.00 31.13  ?  16  LEU C CD2   1 
ATOM 2136 N N     . GLU B 1 17  ? 133.657 116.158 112.643 1.00 35.16  ?  17  GLU C N     1 
ATOM 2137 C CA    . GLU B 1 17  ? 133.368 117.470 113.210 1.00 35.16  ?  17  GLU C CA    1 
ATOM 2138 C C     . GLU B 1 17  ? 132.185 117.405 114.165 1.00 35.16  ?  17  GLU C C     1 
ATOM 2139 O O     . GLU B 1 17  ? 132.185 118.061 115.212 1.00 35.16  ?  17  GLU C O     1 
ATOM 2140 C CB    . GLU B 1 17  ? 133.103 118.481 112.092 1.00 35.16  ?  17  GLU C CB    1 
ATOM 2141 C CG    . GLU B 1 17  ? 132.577 119.871 112.515 1.00 35.16  ?  17  GLU C CG    1 
ATOM 2142 C CD    . GLU B 1 17  ? 133.300 120.539 113.692 1.00 35.16  ?  17  GLU C CD    1 
ATOM 2143 O OE1   . GLU B 1 17  ? 132.893 121.664 114.052 1.00 35.16  ?  17  GLU C OE1   1 
ATOM 2144 O OE2   . GLU B 1 17  ? 134.290 120.003 114.231 1.00 35.16  -1 17  GLU C OE2   1 
ATOM 2145 N N     . ALA B 1 18  ? 131.165 116.620 113.818 1.00 32.78  ?  18  ALA C N     1 
ATOM 2146 C CA    . ALA B 1 18  ? 130.003 116.485 114.689 1.00 32.78  ?  18  ALA C CA    1 
ATOM 2147 C C     . ALA B 1 18  ? 130.367 115.811 116.005 1.00 32.78  ?  18  ALA C C     1 
ATOM 2148 O O     . ALA B 1 18  ? 129.855 116.190 117.064 1.00 32.78  ?  18  ALA C O     1 
ATOM 2149 C CB    . ALA B 1 18  ? 128.900 115.705 113.976 1.00 32.78  ?  18  ALA C CB    1 
ATOM 2150 N N     . LEU B 1 19  ? 131.241 114.809 115.963 1.00 32.92  ?  19  LEU C N     1 
ATOM 2151 C CA    . LEU B 1 19  ? 131.570 114.041 117.158 1.00 32.92  ?  19  LEU C CA    1 
ATOM 2152 C C     . LEU B 1 19  ? 132.720 114.627 117.971 1.00 32.92  ?  19  LEU C C     1 
ATOM 2153 O O     . LEU B 1 19  ? 132.992 114.128 119.066 1.00 32.92  ?  19  LEU C O     1 
ATOM 2154 C CB    . LEU B 1 19  ? 131.915 112.599 116.778 1.00 32.92  ?  19  LEU C CB    1 
ATOM 2155 C CG    . LEU B 1 19  ? 130.794 111.757 116.176 1.00 32.92  ?  19  LEU C CG    1 
ATOM 2156 C CD1   . LEU B 1 19  ? 131.204 110.299 116.117 1.00 32.92  ?  19  LEU C CD1   1 
ATOM 2157 C CD2   . LEU B 1 19  ? 129.523 111.922 116.980 1.00 32.92  ?  19  LEU C CD2   1 
ATOM 2158 N N     . LYS B 1 20  ? 133.400 115.663 117.477 1.00 36.11  ?  20  LYS C N     1 
ATOM 2159 C CA    . LYS B 1 20  ? 134.635 116.096 118.124 1.00 36.11  ?  20  LYS C CA    1 
ATOM 2160 C C     . LYS B 1 20  ? 134.394 116.898 119.398 1.00 36.11  ?  20  LYS C C     1 
ATOM 2161 O O     . LYS B 1 20  ? 135.172 116.776 120.350 1.00 36.11  ?  20  LYS C O     1 
ATOM 2162 C CB    . LYS B 1 20  ? 135.493 116.900 117.141 1.00 36.11  ?  20  LYS C CB    1 
ATOM 2163 C CG    . LYS B 1 20  ? 135.285 118.405 117.169 1.00 36.11  ?  20  LYS C CG    1 
ATOM 2164 C CD    . LYS B 1 20  ? 136.587 119.148 116.934 1.00 36.11  ?  20  LYS C CD    1 
ATOM 2165 C CE    . LYS B 1 20  ? 136.397 120.647 117.086 1.00 36.11  ?  20  LYS C CE    1 
ATOM 2166 N NZ    . LYS B 1 20  ? 135.388 121.176 116.128 1.00 36.11  1  20  LYS C NZ    1 
ATOM 2167 N N     . ASP B 1 21  ? 133.339 117.710 119.451 1.00 39.50  ?  21  ASP C N     1 
ATOM 2168 C CA    . ASP B 1 21  ? 133.130 118.602 120.584 1.00 39.50  ?  21  ASP C CA    1 
ATOM 2169 C C     . ASP B 1 21  ? 132.289 117.981 121.688 1.00 39.50  ?  21  ASP C C     1 
ATOM 2170 O O     . ASP B 1 21  ? 132.127 118.600 122.745 1.00 39.50  ?  21  ASP C O     1 
ATOM 2171 C CB    . ASP B 1 21  ? 132.476 119.906 120.118 1.00 39.50  ?  21  ASP C CB    1 
ATOM 2172 C CG    . ASP B 1 21  ? 131.410 119.679 119.067 1.00 39.50  ?  21  ASP C CG    1 
ATOM 2173 O OD1   . ASP B 1 21  ? 130.941 118.529 118.934 1.00 39.50  ?  21  ASP C OD1   1 
ATOM 2174 O OD2   . ASP B 1 21  ? 131.043 120.648 118.372 1.00 39.50  -1 21  ASP C OD2   1 
ATOM 2175 N N     . LEU B 1 22  ? 131.756 116.781 121.472 1.00 39.15  ?  22  LEU C N     1 
ATOM 2176 C CA    . LEU B 1 22  ? 130.950 116.094 122.467 1.00 39.15  ?  22  LEU C CA    1 
ATOM 2177 C C     . LEU B 1 22  ? 131.627 114.867 123.052 1.00 39.15  ?  22  LEU C C     1 
ATOM 2178 O O     . LEU B 1 22  ? 131.238 114.424 124.136 1.00 39.15  ?  22  LEU C O     1 
ATOM 2179 C CB    . LEU B 1 22  ? 129.608 115.669 121.854 1.00 39.15  ?  22  LEU C CB    1 
ATOM 2180 C CG    . LEU B 1 22  ? 128.486 115.205 122.784 1.00 39.15  ?  22  LEU C CG    1 
ATOM 2181 C CD1   . LEU B 1 22  ? 127.932 116.376 123.568 1.00 39.15  ?  22  LEU C CD1   1 
ATOM 2182 C CD2   . LEU B 1 22  ? 127.394 114.526 121.983 1.00 39.15  ?  22  LEU C CD2   1 
ATOM 2183 N N     . ILE B 1 23  ? 132.630 114.320 122.376 1.00 39.64  ?  23  ILE C N     1 
ATOM 2184 C CA    . ILE B 1 23  ? 133.175 113.009 122.698 1.00 39.64  ?  23  ILE C CA    1 
ATOM 2185 C C     . ILE B 1 23  ? 134.692 113.092 122.646 1.00 39.64  ?  23  ILE C C     1 
ATOM 2186 O O     . ILE B 1 23  ? 135.258 113.722 121.747 1.00 39.64  ?  23  ILE C O     1 
ATOM 2187 C CB    . ILE B 1 23  ? 132.648 111.944 121.715 1.00 39.64  ?  23  ILE C CB    1 
ATOM 2188 C CG1   . ILE B 1 23  ? 131.153 111.727 121.932 1.00 39.64  ?  23  ILE C CG1   1 
ATOM 2189 C CG2   . ILE B 1 23  ? 133.375 110.632 121.906 1.00 39.64  ?  23  ILE C CG2   1 
ATOM 2190 C CD1   . ILE B 1 23  ? 130.533 110.788 120.939 1.00 39.64  ?  23  ILE C CD1   1 
ATOM 2191 N N     . ASN B 1 24  ? 135.352 112.470 123.620 1.00 45.79  ?  24  ASN C N     1 
ATOM 2192 C CA    . ASN B 1 24  ? 136.807 112.421 123.668 1.00 45.79  ?  24  ASN C CA    1 
ATOM 2193 C C     . ASN B 1 24  ? 137.369 111.119 123.110 1.00 45.79  ?  24  ASN C C     1 
ATOM 2194 O O     . ASN B 1 24  ? 138.228 111.145 122.225 1.00 45.79  ?  24  ASN C O     1 
ATOM 2195 C CB    . ASN B 1 24  ? 137.284 112.631 125.109 1.00 45.79  ?  24  ASN C CB    1 
ATOM 2196 C CG    . ASN B 1 24  ? 136.445 111.867 126.113 1.00 45.79  ?  24  ASN C CG    1 
ATOM 2197 O OD1   . ASN B 1 24  ? 136.452 110.637 126.140 1.00 45.79  ?  24  ASN C OD1   1 
ATOM 2198 N ND2   . ASN B 1 24  ? 135.705 112.597 126.939 1.00 45.79  ?  24  ASN C ND2   1 
ATOM 2199 N N     . GLU B 1 25  ? 136.898 109.978 123.606 1.00 47.42  ?  25  GLU C N     1 
ATOM 2200 C CA    . GLU B 1 25  ? 137.342 108.669 123.149 1.00 47.42  ?  25  GLU C CA    1 
ATOM 2201 C C     . GLU B 1 25  ? 136.133 107.838 122.749 1.00 47.42  ?  25  GLU C C     1 
ATOM 2202 O O     . GLU B 1 25  ? 135.036 108.029 123.281 1.00 47.42  ?  25  GLU C O     1 
ATOM 2203 C CB    . GLU B 1 25  ? 138.137 107.934 124.234 1.00 47.42  ?  25  GLU C CB    1 
ATOM 2204 C CG    . GLU B 1 25  ? 139.074 108.811 125.048 1.00 47.42  ?  25  GLU C CG    1 
ATOM 2205 C CD    . GLU B 1 25  ? 140.042 109.594 124.184 1.00 47.42  ?  25  GLU C CD    1 
ATOM 2206 O OE1   . GLU B 1 25  ? 140.730 108.972 123.348 1.00 47.42  ?  25  GLU C OE1   1 
ATOM 2207 O OE2   . GLU B 1 25  ? 140.121 110.830 124.346 1.00 47.42  -1 25  GLU C OE2   1 
ATOM 2208 N N     . ALA B 1 26  ? 136.335 106.914 121.814 1.00 41.94  ?  26  ALA C N     1 
ATOM 2209 C CA    . ALA B 1 26  ? 135.258 106.054 121.350 1.00 41.94  ?  26  ALA C CA    1 
ATOM 2210 C C     . ALA B 1 26  ? 135.811 104.685 120.991 1.00 41.94  ?  26  ALA C C     1 
ATOM 2211 O O     . ALA B 1 26  ? 136.997 104.527 120.698 1.00 41.94  ?  26  ALA C O     1 
ATOM 2212 C CB    . ALA B 1 26  ? 134.533 106.656 120.142 1.00 41.94  ?  26  ALA C CB    1 
ATOM 2213 N N     . CYS B 1 27  ? 134.927 103.692 121.015 1.00 43.81  ?  27  CYS C N     1 
ATOM 2214 C CA    . CYS B 1 27  ? 135.264 102.323 120.636 1.00 43.81  ?  27  CYS C CA    1 
ATOM 2215 C C     . CYS B 1 27  ? 134.836 102.124 119.188 1.00 43.81  ?  27  CYS C C     1 
ATOM 2216 O O     . CYS B 1 27  ? 133.668 101.850 118.905 1.00 43.81  ?  27  CYS C O     1 
ATOM 2217 C CB    . CYS B 1 27  ? 134.590 101.319 121.563 1.00 43.81  ?  27  CYS C CB    1 
ATOM 2218 S SG    . CYS B 1 27  ? 135.314 99.664  121.510 1.00 43.81  ?  27  CYS C SG    1 
ATOM 2219 N N     . TRP B 1 28  ? 135.791 102.250 118.271 1.00 37.61  ?  28  TRP C N     1 
ATOM 2220 C CA    . TRP B 1 28  ? 135.506 102.160 116.846 1.00 37.61  ?  28  TRP C CA    1 
ATOM 2221 C C     . TRP B 1 28  ? 135.234 100.722 116.429 1.00 37.61  ?  28  TRP C C     1 
ATOM 2222 O O     . TRP B 1 28  ? 136.073 100.095 115.777 1.00 37.61  ?  28  TRP C O     1 
ATOM 2223 C CB    . TRP B 1 28  ? 136.673 102.724 116.038 1.00 37.61  ?  28  TRP C CB    1 
ATOM 2224 C CG    . TRP B 1 28  ? 136.251 103.574 114.897 1.00 37.61  ?  28  TRP C CG    1 
ATOM 2225 C CD1   . TRP B 1 28  ? 135.970 103.162 113.631 1.00 37.61  ?  28  TRP C CD1   1 
ATOM 2226 C CD2   . TRP B 1 28  ? 136.067 104.991 114.910 1.00 37.61  ?  28  TRP C CD2   1 
ATOM 2227 N NE1   . TRP B 1 28  ? 135.617 104.235 112.852 1.00 37.61  ?  28  TRP C NE1   1 
ATOM 2228 C CE2   . TRP B 1 28  ? 135.669 105.371 113.615 1.00 37.61  ?  28  TRP C CE2   1 
ATOM 2229 C CE3   . TRP B 1 28  ? 136.198 105.976 115.892 1.00 37.61  ?  28  TRP C CE3   1 
ATOM 2230 C CZ2   . TRP B 1 28  ? 135.400 106.693 113.276 1.00 37.61  ?  28  TRP C CZ2   1 
ATOM 2231 C CZ3   . TRP B 1 28  ? 135.932 107.287 115.553 1.00 37.61  ?  28  TRP C CZ3   1 
ATOM 2232 C CH2   . TRP B 1 28  ? 135.537 107.634 114.256 1.00 37.61  ?  28  TRP C CH2   1 
ATOM 2233 N N     . ASP B 1 29  ? 134.072 100.193 116.800 1.00 31.05  ?  29  ASP C N     1 
ATOM 2234 C CA    . ASP B 1 29  ? 133.735 98.819  116.458 1.00 31.05  ?  29  ASP C CA    1 
ATOM 2235 C C     . ASP B 1 29  ? 133.678 98.644  114.947 1.00 31.05  ?  29  ASP C C     1 
ATOM 2236 O O     . ASP B 1 29  ? 133.090 99.463  114.236 1.00 31.05  ?  29  ASP C O     1 
ATOM 2237 C CB    . ASP B 1 29  ? 132.397 98.436  117.089 1.00 31.05  ?  29  ASP C CB    1 
ATOM 2238 C CG    . ASP B 1 29  ? 132.103 96.951  116.989 1.00 31.05  ?  29  ASP C CG    1 
ATOM 2239 O OD1   . ASP B 1 29  ? 132.847 96.230  116.292 1.00 31.05  ?  29  ASP C OD1   1 
ATOM 2240 O OD2   . ASP B 1 29  ? 131.118 96.501  117.611 1.00 31.05  -1 29  ASP C OD2   1 
ATOM 2241 N N     . ILE B 1 30  ? 134.294 97.571  114.459 1.00 35.38  ?  30  ILE C N     1 
ATOM 2242 C CA    . ILE B 1 30  ? 134.300 97.230  113.044 1.00 35.38  ?  30  ILE C CA    1 
ATOM 2243 C C     . ILE B 1 30  ? 133.830 95.792  112.897 1.00 35.38  ?  30  ILE C C     1 
ATOM 2244 O O     . ILE B 1 30  ? 134.075 94.948  113.763 1.00 35.38  ?  30  ILE C O     1 
ATOM 2245 C CB    . ILE B 1 30  ? 135.696 97.407  112.406 1.00 35.38  ?  30  ILE C CB    1 
ATOM 2246 C CG1   . ILE B 1 30  ? 136.332 98.721  112.856 1.00 35.38  ?  30  ILE C CG1   1 
ATOM 2247 C CG2   . ILE B 1 30  ? 135.607 97.361  110.893 1.00 35.38  ?  30  ILE C CG2   1 
ATOM 2248 C CD1   . ILE B 1 30  ? 135.670 99.944  112.277 1.00 35.38  ?  30  ILE C CD1   1 
ATOM 2249 N N     . SER B 1 31  ? 133.150 95.514  111.790 1.00 33.17  ?  31  SER C N     1 
ATOM 2250 C CA    . SER B 1 31  ? 132.664 94.173  111.507 1.00 33.17  ?  31  SER C CA    1 
ATOM 2251 C C     . SER B 1 31  ? 132.614 93.990  109.996 1.00 33.17  ?  31  SER C C     1 
ATOM 2252 O O     . SER B 1 31  ? 133.139 94.809  109.236 1.00 33.17  ?  31  SER C O     1 
ATOM 2253 C CB    . SER B 1 31  ? 131.298 93.941  112.162 1.00 33.17  ?  31  SER C CB    1 
ATOM 2254 O OG    . SER B 1 31  ? 130.584 92.917  111.492 1.00 33.17  ?  31  SER C OG    1 
ATOM 2255 N N     . SER B 1 32  ? 131.978 92.909  109.559 1.00 31.80  ?  32  SER C N     1 
ATOM 2256 C CA    . SER B 1 32  ? 131.820 92.623  108.141 1.00 31.80  ?  32  SER C CA    1 
ATOM 2257 C C     . SER B 1 32  ? 130.616 93.325  107.529 1.00 31.80  ?  32  SER C C     1 
ATOM 2258 O O     . SER B 1 32  ? 130.381 93.184  106.325 1.00 31.80  ?  32  SER C O     1 
ATOM 2259 C CB    . SER B 1 32  ? 131.703 91.113  107.918 1.00 31.80  ?  32  SER C CB    1 
ATOM 2260 O OG    . SER B 1 32  ? 130.849 90.524  108.882 1.00 31.80  ?  32  SER C OG    1 
ATOM 2261 N N     . SER B 1 33  ? 129.850 94.070  108.325 1.00 29.42  ?  33  SER C N     1 
ATOM 2262 C CA    . SER B 1 33  ? 128.690 94.793  107.830 1.00 29.42  ?  33  SER C CA    1 
ATOM 2263 C C     . SER B 1 33  ? 128.887 96.300  107.792 1.00 29.42  ?  33  SER C C     1 
ATOM 2264 O O     . SER B 1 33  ? 128.070 96.996  107.179 1.00 29.42  ?  33  SER C O     1 
ATOM 2265 C CB    . SER B 1 33  ? 127.458 94.474  108.687 1.00 29.42  ?  33  SER C CB    1 
ATOM 2266 O OG    . SER B 1 33  ? 127.241 95.487  109.653 1.00 29.42  ?  33  SER C OG    1 
ATOM 2267 N N     . GLY B 1 34  ? 129.924 96.819  108.424 1.00 31.19  ?  34  GLY C N     1 
ATOM 2268 C CA    . GLY B 1 34  ? 130.207 98.242  108.416 1.00 31.19  ?  34  GLY C CA    1 
ATOM 2269 C C     . GLY B 1 34  ? 130.541 98.743  109.807 1.00 31.19  ?  34  GLY C C     1 
ATOM 2270 O O     . GLY B 1 34  ? 130.322 98.071  110.814 1.00 31.19  ?  34  GLY C O     1 
ATOM 2271 N N     . VAL B 1 35  ? 131.087 99.960  109.859 1.00 21.72  ?  35  VAL C N     1 
ATOM 2272 C CA    . VAL B 1 35  ? 131.439 100.566 111.135 1.00 21.72  ?  35  VAL C CA    1 
ATOM 2273 C C     . VAL B 1 35  ? 130.183 100.797 111.959 1.00 21.72  ?  35  VAL C C     1 
ATOM 2274 O O     . VAL B 1 35  ? 129.176 101.318 111.464 1.00 21.72  ?  35  VAL C O     1 
ATOM 2275 C CB    . VAL B 1 35  ? 132.199 101.882 110.909 1.00 21.72  ?  35  VAL C CB    1 
ATOM 2276 C CG1   . VAL B 1 35  ? 132.709 102.430 112.228 1.00 21.72  ?  35  VAL C CG1   1 
ATOM 2277 C CG2   . VAL B 1 35  ? 133.343 101.671 109.936 1.00 21.72  ?  35  VAL C CG2   1 
ATOM 2278 N N     . ASN B 1 36  ? 130.235 100.401 113.230 1.00 31.23  ?  36  ASN C N     1 
ATOM 2279 C CA    . ASN B 1 36  ? 129.118 100.564 114.160 1.00 31.23  ?  36  ASN C CA    1 
ATOM 2280 C C     . ASN B 1 36  ? 129.662 101.205 115.431 1.00 31.23  ?  36  ASN C C     1 
ATOM 2281 O O     . ASN B 1 36  ? 130.002 100.509 116.389 1.00 31.23  ?  36  ASN C O     1 
ATOM 2282 C CB    . ASN B 1 36  ? 128.446 99.229  114.447 1.00 31.23  ?  36  ASN C CB    1 
ATOM 2283 C CG    . ASN B 1 36  ? 127.621 98.730  113.282 1.00 31.23  ?  36  ASN C CG    1 
ATOM 2284 O OD1   . ASN B 1 36  ? 126.393 98.807  113.299 1.00 31.23  ?  36  ASN C OD1   1 
ATOM 2285 N ND2   . ASN B 1 36  ? 128.291 98.214  112.259 1.00 31.23  ?  36  ASN C ND2   1 
ATOM 2286 N N     . LEU B 1 37  ? 129.734 102.530 115.443 1.00 29.71  ?  37  LEU C N     1 
ATOM 2287 C CA    . LEU B 1 37  ? 130.211 103.254 116.610 1.00 29.71  ?  37  LEU C CA    1 
ATOM 2288 C C     . LEU B 1 37  ? 129.107 103.353 117.652 1.00 29.71  ?  37  LEU C C     1 
ATOM 2289 O O     . LEU B 1 37  ? 127.928 103.496 117.318 1.00 29.71  ?  37  LEU C O     1 
ATOM 2290 C CB    . LEU B 1 37  ? 130.687 104.654 116.224 1.00 29.71  ?  37  LEU C CB    1 
ATOM 2291 C CG    . LEU B 1 37  ? 131.696 105.324 117.158 1.00 29.71  ?  37  LEU C CG    1 
ATOM 2292 C CD1   . LEU B 1 37  ? 132.615 106.235 116.368 1.00 29.71  ?  37  LEU C CD1   1 
ATOM 2293 C CD2   . LEU B 1 37  ? 130.997 106.103 118.257 1.00 29.71  ?  37  LEU C CD2   1 
ATOM 2294 N N     . GLN B 1 38  ? 129.501 103.267 118.919 1.00 39.14  ?  38  GLN C N     1 
ATOM 2295 C CA    . GLN B 1 38  ? 128.583 103.480 120.034 1.00 39.14  ?  38  GLN C CA    1 
ATOM 2296 C C     . GLN B 1 38  ? 129.428 103.911 121.221 1.00 39.14  ?  38  GLN C C     1 
ATOM 2297 O O     . GLN B 1 38  ? 130.067 103.073 121.863 1.00 39.14  ?  38  GLN C O     1 
ATOM 2298 C CB    . GLN B 1 38  ? 127.789 102.218 120.349 1.00 39.14  ?  38  GLN C CB    1 
ATOM 2299 C CG    . GLN B 1 38  ? 127.034 102.274 121.663 1.00 39.14  ?  38  GLN C CG    1 
ATOM 2300 C CD    . GLN B 1 38  ? 125.769 101.448 121.638 1.00 39.14  ?  38  GLN C CD    1 
ATOM 2301 O OE1   . GLN B 1 38  ? 125.620 100.546 120.814 1.00 39.14  ?  38  GLN C OE1   1 
ATOM 2302 N NE2   . GLN B 1 38  ? 124.848 101.749 122.544 1.00 39.14  ?  38  GLN C NE2   1 
ATOM 2303 N N     . SER B 1 39  ? 129.434 105.209 121.512 1.00 35.16  ?  39  SER C N     1 
ATOM 2304 C CA    . SER B 1 39  ? 130.335 105.730 122.529 1.00 35.16  ?  39  SER C CA    1 
ATOM 2305 C C     . SER B 1 39  ? 129.579 106.503 123.595 1.00 35.16  ?  39  SER C C     1 
ATOM 2306 O O     . SER B 1 39  ? 128.369 106.327 123.760 1.00 35.16  ?  39  SER C O     1 
ATOM 2307 C CB    . SER B 1 39  ? 131.405 106.616 121.899 1.00 35.16  ?  39  SER C CB    1 
ATOM 2308 O OG    . SER B 1 39  ? 130.932 107.937 121.766 1.00 35.16  ?  39  SER C OG    1 
ATOM 2309 N N     . MET B 1 40  ? 130.287 107.353 124.332 1.00 40.47  ?  40  MET C N     1 
ATOM 2310 C CA    . MET B 1 40  ? 129.736 107.956 125.529 1.00 40.47  ?  40  MET C CA    1 
ATOM 2311 C C     . MET B 1 40  ? 130.050 109.446 125.531 1.00 40.47  ?  40  MET C C     1 
ATOM 2312 O O     . MET B 1 40  ? 130.772 109.955 124.672 1.00 40.47  ?  40  MET C O     1 
ATOM 2313 C CB    . MET B 1 40  ? 130.318 107.293 126.783 1.00 40.47  ?  40  MET C CB    1 
ATOM 2314 C CG    . MET B 1 40  ? 129.394 106.292 127.458 1.00 40.47  ?  40  MET C CG    1 
ATOM 2315 S SD    . MET B 1 40  ? 127.645 106.636 127.709 1.00 40.47  ?  40  MET C SD    1 
ATOM 2316 C CE    . MET B 1 40  ? 127.551 108.385 128.068 1.00 40.47  ?  40  MET C CE    1 
ATOM 2317 N N     . ASP B 1 41  ? 129.487 110.145 126.509 1.00 41.22  ?  41  ASP C N     1 
ATOM 2318 C CA    . ASP B 1 41  ? 129.827 111.525 126.807 1.00 41.22  ?  41  ASP C CA    1 
ATOM 2319 C C     . ASP B 1 41  ? 130.405 111.564 128.216 1.00 41.22  ?  41  ASP C C     1 
ATOM 2320 O O     . ASP B 1 41  ? 130.064 110.734 129.063 1.00 41.22  ?  41  ASP C O     1 
ATOM 2321 C CB    . ASP B 1 41  ? 128.590 112.429 126.684 1.00 41.22  ?  41  ASP C CB    1 
ATOM 2322 C CG    . ASP B 1 41  ? 128.755 113.789 127.364 1.00 41.22  ?  41  ASP C CG    1 
ATOM 2323 O OD1   . ASP B 1 41  ? 127.738 114.503 127.477 1.00 41.22  ?  41  ASP C OD1   1 
ATOM 2324 O OD2   . ASP B 1 41  ? 129.883 114.188 127.722 1.00 41.22  -1 41  ASP C OD2   1 
ATOM 2325 N N     . SER B 1 42  ? 131.290 112.534 128.459 1.00 42.47  ?  42  SER C N     1 
ATOM 2326 C CA    . SER B 1 42  ? 131.955 112.621 129.756 1.00 42.47  ?  42  SER C CA    1 
ATOM 2327 C C     . SER B 1 42  ? 130.953 112.835 130.883 1.00 42.47  ?  42  SER C C     1 
ATOM 2328 O O     . SER B 1 42  ? 131.073 112.226 131.952 1.00 42.47  ?  42  SER C O     1 
ATOM 2329 C CB    . SER B 1 42  ? 132.988 113.745 129.738 1.00 42.47  ?  42  SER C CB    1 
ATOM 2330 O OG    . SER B 1 42  ? 133.644 113.811 128.484 1.00 42.47  ?  42  SER C OG    1 
ATOM 2331 N N     . SER B 1 43  ? 129.952 113.687 130.662 1.00 42.48  ?  43  SER C N     1 
ATOM 2332 C CA    . SER B 1 43  ? 128.969 113.971 131.699 1.00 42.48  ?  43  SER C CA    1 
ATOM 2333 C C     . SER B 1 43  ? 128.015 112.810 131.939 1.00 42.48  ?  43  SER C C     1 
ATOM 2334 O O     . SER B 1 43  ? 127.185 112.898 132.849 1.00 42.48  ?  43  SER C O     1 
ATOM 2335 C CB    . SER B 1 43  ? 128.173 115.225 131.346 1.00 42.48  ?  43  SER C CB    1 
ATOM 2336 O OG    . SER B 1 43  ? 126.942 114.887 130.735 1.00 42.48  ?  43  SER C OG    1 
ATOM 2337 N N     . HIS B 1 44  ? 128.093 111.752 131.130 1.00 45.01  ?  44  HIS C N     1 
ATOM 2338 C CA    . HIS B 1 44  ? 127.380 110.502 131.385 1.00 45.01  ?  44  HIS C CA    1 
ATOM 2339 C C     . HIS B 1 44  ? 125.866 110.690 131.295 1.00 45.01  ?  44  HIS C C     1 
ATOM 2340 O O     . HIS B 1 44  ? 125.105 110.055 132.024 1.00 45.01  ?  44  HIS C O     1 
ATOM 2341 C CB    . HIS B 1 44  ? 127.780 109.921 132.744 1.00 45.01  ?  44  HIS C CB    1 
ATOM 2342 C CG    . HIS B 1 44  ? 128.140 108.469 132.708 1.00 45.01  ?  44  HIS C CG    1 
ATOM 2343 N ND1   . HIS B 1 44  ? 127.275 107.495 132.262 1.00 45.01  ?  44  HIS C ND1   1 
ATOM 2344 C CD2   . HIS B 1 44  ? 129.278 107.828 133.062 1.00 45.01  ?  44  HIS C CD2   1 
ATOM 2345 C CE1   . HIS B 1 44  ? 127.862 106.315 132.350 1.00 45.01  ?  44  HIS C CE1   1 
ATOM 2346 N NE2   . HIS B 1 44  ? 129.080 106.490 132.829 1.00 45.01  ?  44  HIS C NE2   1 
ATOM 2347 N N     . VAL B 1 45  ? 125.426 111.568 130.394 1.00 41.00  ?  45  VAL C N     1 
ATOM 2348 C CA    . VAL B 1 45  ? 123.999 111.816 130.205 1.00 41.00  ?  45  VAL C CA    1 
ATOM 2349 C C     . VAL B 1 45  ? 123.541 111.646 128.765 1.00 41.00  ?  45  VAL C C     1 
ATOM 2350 O O     . VAL B 1 45  ? 122.339 111.430 128.528 1.00 41.00  ?  45  VAL C O     1 
ATOM 2351 C CB    . VAL B 1 45  ? 123.622 113.224 130.720 1.00 41.00  ?  45  VAL C CB    1 
ATOM 2352 C CG1   . VAL B 1 45  ? 123.984 114.278 129.696 1.00 41.00  ?  45  VAL C CG1   1 
ATOM 2353 C CG2   . VAL B 1 45  ? 122.144 113.294 131.060 1.00 41.00  ?  45  VAL C CG2   1 
ATOM 2354 N N     . SER B 1 46  ? 124.421 111.718 127.770 1.00 36.15  ?  46  SER C N     1 
ATOM 2355 C CA    . SER B 1 46  ? 124.035 111.622 126.370 1.00 36.15  ?  46  SER C CA    1 
ATOM 2356 C C     . SER B 1 46  ? 124.779 110.475 125.704 1.00 36.15  ?  46  SER C C     1 
ATOM 2357 O O     . SER B 1 46  ? 125.979 110.289 125.926 1.00 36.15  ?  46  SER C O     1 
ATOM 2358 C CB    . SER B 1 46  ? 124.325 112.925 125.628 1.00 36.15  ?  46  SER C CB    1 
ATOM 2359 O OG    . SER B 1 46  ? 125.679 112.980 125.218 1.00 36.15  ?  46  SER C OG    1 
ATOM 2360 N N     . LEU B 1 47  ? 124.065 109.716 124.879 1.00 38.21  ?  47  LEU C N     1 
ATOM 2361 C CA    . LEU B 1 47  ? 124.614 108.553 124.199 1.00 38.21  ?  47  LEU C CA    1 
ATOM 2362 C C     . LEU B 1 47  ? 124.498 108.746 122.694 1.00 38.21  ?  47  LEU C C     1 
ATOM 2363 O O     . LEU B 1 47  ? 123.440 109.133 122.189 1.00 38.21  ?  47  LEU C O     1 
ATOM 2364 C CB    . LEU B 1 47  ? 123.888 107.277 124.635 1.00 38.21  ?  47  LEU C CB    1 
ATOM 2365 C CG    . LEU B 1 47  ? 123.841 106.090 123.676 1.00 38.21  ?  47  LEU C CG    1 
ATOM 2366 C CD1   . LEU B 1 47  ? 125.220 105.491 123.505 1.00 38.21  ?  47  LEU C CD1   1 
ATOM 2367 C CD2   . LEU B 1 47  ? 122.871 105.044 124.189 1.00 38.21  ?  47  LEU C CD2   1 
ATOM 2368 N N     . VAL B 1 48  ? 125.589 108.476 121.982 1.00 36.48  ?  48  VAL C N     1 
ATOM 2369 C CA    . VAL B 1 48  ? 125.672 108.687 120.543 1.00 36.48  ?  48  VAL C CA    1 
ATOM 2370 C C     . VAL B 1 48  ? 125.849 107.339 119.859 1.00 36.48  ?  48  VAL C C     1 
ATOM 2371 O O     . VAL B 1 48  ? 126.371 106.389 120.449 1.00 36.48  ?  48  VAL C O     1 
ATOM 2372 C CB    . VAL B 1 48  ? 126.830 109.644 120.188 1.00 36.48  ?  48  VAL C CB    1 
ATOM 2373 C CG1   . VAL B 1 48  ? 126.751 110.083 118.741 1.00 36.48  ?  48  VAL C CG1   1 
ATOM 2374 C CG2   . VAL B 1 48  ? 126.814 110.848 121.109 1.00 36.48  ?  48  VAL C CG2   1 
ATOM 2375 N N     . GLN B 1 49  ? 125.410 107.257 118.605 1.00 54.26  ?  49  GLN C N     1 
ATOM 2376 C CA    . GLN B 1 49  ? 125.551 106.034 117.832 1.00 54.26  ?  49  GLN C CA    1 
ATOM 2377 C C     . GLN B 1 49  ? 125.784 106.395 116.373 1.00 54.26  ?  49  GLN C C     1 
ATOM 2378 O O     . GLN B 1 49  ? 125.368 107.459 115.911 1.00 54.26  ?  49  GLN C O     1 
ATOM 2379 C CB    . GLN B 1 49  ? 124.317 105.137 117.978 1.00 54.26  ?  49  GLN C CB    1 
ATOM 2380 C CG    . GLN B 1 49  ? 124.467 103.763 117.356 1.00 54.26  ?  49  GLN C CG    1 
ATOM 2381 C CD    . GLN B 1 49  ? 123.140 103.150 116.972 1.00 54.26  ?  49  GLN C CD    1 
ATOM 2382 O OE1   . GLN B 1 49  ? 122.205 103.117 117.770 1.00 54.26  ?  49  GLN C OE1   1 
ATOM 2383 N NE2   . GLN B 1 49  ? 123.048 102.662 115.741 1.00 54.26  ?  49  GLN C NE2   1 
ATOM 2384 N N     . LEU B 1 50  ? 126.463 105.502 115.655 1.00 33.43  ?  50  LEU C N     1 
ATOM 2385 C CA    . LEU B 1 50  ? 126.777 105.696 114.248 1.00 33.43  ?  50  LEU C CA    1 
ATOM 2386 C C     . LEU B 1 50  ? 126.817 104.338 113.564 1.00 33.43  ?  50  LEU C C     1 
ATOM 2387 O O     . LEU B 1 50  ? 127.389 103.386 114.100 1.00 33.43  ?  50  LEU C O     1 
ATOM 2388 C CB    . LEU B 1 50  ? 128.113 106.424 114.077 1.00 33.43  ?  50  LEU C CB    1 
ATOM 2389 C CG    . LEU B 1 50  ? 128.679 106.540 112.666 1.00 33.43  ?  50  LEU C CG    1 
ATOM 2390 C CD1   . LEU B 1 50  ? 127.659 107.157 111.735 1.00 33.43  ?  50  LEU C CD1   1 
ATOM 2391 C CD2   . LEU B 1 50  ? 129.950 107.364 112.684 1.00 33.43  ?  50  LEU C CD2   1 
ATOM 2392 N N     . THR B 1 51  ? 126.208 104.250 112.384 1.00 32.88  ?  51  THR C N     1 
ATOM 2393 C CA    . THR B 1 51  ? 125.969 102.973 111.716 1.00 32.88  ?  51  THR C CA    1 
ATOM 2394 C C     . THR B 1 51  ? 126.332 103.050 110.237 1.00 32.88  ?  51  THR C C     1 
ATOM 2395 O O     . THR B 1 51  ? 125.530 102.725 109.361 1.00 32.88  ?  51  THR C O     1 
ATOM 2396 C CB    . THR B 1 51  ? 124.519 102.535 111.887 1.00 32.88  ?  51  THR C CB    1 
ATOM 2397 O OG1   . THR B 1 51  ? 124.064 102.896 113.197 1.00 32.88  ?  51  THR C OG1   1 
ATOM 2398 C CG2   . THR B 1 51  ? 124.395 101.027 111.721 1.00 32.88  ?  51  THR C CG2   1 
ATOM 2399 N N     . LEU B 1 52  ? 127.543 103.514 109.935 1.00 32.47  ?  52  LEU C N     1 
ATOM 2400 C CA    . LEU B 1 52  ? 128.012 103.521 108.553 1.00 32.47  ?  52  LEU C CA    1 
ATOM 2401 C C     . LEU B 1 52  ? 127.944 102.116 107.968 1.00 32.47  ?  52  LEU C C     1 
ATOM 2402 O O     . LEU B 1 52  ? 128.641 101.208 108.428 1.00 32.47  ?  52  LEU C O     1 
ATOM 2403 C CB    . LEU B 1 52  ? 129.442 104.053 108.481 1.00 32.47  ?  52  LEU C CB    1 
ATOM 2404 C CG    . LEU B 1 52  ? 129.695 105.467 109.000 1.00 32.47  ?  52  LEU C CG    1 
ATOM 2405 C CD1   . LEU B 1 52  ? 131.183 105.704 109.184 1.00 32.47  ?  52  LEU C CD1   1 
ATOM 2406 C CD2   . LEU B 1 52  ? 129.100 106.499 108.069 1.00 32.47  ?  52  LEU C CD2   1 
ATOM 2407 N N     . ARG B 1 53  ? 127.109 101.941 106.949 1.00 36.23  ?  53  ARG C N     1 
ATOM 2408 C CA    . ARG B 1 53  ? 126.871 100.628 106.364 1.00 36.23  ?  53  ARG C CA    1 
ATOM 2409 C C     . ARG B 1 53  ? 128.062 100.226 105.497 1.00 36.23  ?  53  ARG C C     1 
ATOM 2410 O O     . ARG B 1 53  ? 129.085 100.912 105.445 1.00 36.23  ?  53  ARG C O     1 
ATOM 2411 C CB    . ARG B 1 53  ? 125.565 100.635 105.576 1.00 36.23  ?  53  ARG C CB    1 
ATOM 2412 C CG    . ARG B 1 53  ? 124.486 99.734  106.147 1.00 36.23  ?  53  ARG C CG    1 
ATOM 2413 C CD    . ARG B 1 53  ? 123.279 99.692  105.227 1.00 36.23  ?  53  ARG C CD    1 
ATOM 2414 N NE    . ARG B 1 53  ? 122.992 101.009 104.672 1.00 36.23  ?  53  ARG C NE    1 
ATOM 2415 C CZ    . ARG B 1 53  ? 122.356 101.974 105.322 1.00 36.23  ?  53  ARG C CZ    1 
ATOM 2416 N NH1   . ARG B 1 53  ? 121.900 101.795 106.551 1.00 36.23  1  53  ARG C NH1   1 
ATOM 2417 N NH2   . ARG B 1 53  ? 122.177 103.149 104.726 1.00 36.23  ?  53  ARG C NH2   1 
ATOM 2418 N N     . SER B 1 54  ? 127.939 99.098  104.801 1.00 37.19  ?  54  SER C N     1 
ATOM 2419 C CA    . SER B 1 54  ? 129.018 98.586  103.966 1.00 37.19  ?  54  SER C CA    1 
ATOM 2420 C C     . SER B 1 54  ? 128.831 98.877  102.486 1.00 37.19  ?  54  SER C C     1 
ATOM 2421 O O     . SER B 1 54  ? 129.824 98.995  101.762 1.00 37.19  ?  54  SER C O     1 
ATOM 2422 C CB    . SER B 1 54  ? 129.164 97.073  104.153 1.00 37.19  ?  54  SER C CB    1 
ATOM 2423 O OG    . SER B 1 54  ? 129.730 96.477  103.000 1.00 37.19  ?  54  SER C OG    1 
ATOM 2424 N N     . GLU B 1 55  ? 127.588 98.988  102.016 1.00 42.55  ?  55  GLU C N     1 
ATOM 2425 C CA    . GLU B 1 55  ? 127.358 99.226  100.596 1.00 42.55  ?  55  GLU C CA    1 
ATOM 2426 C C     . GLU B 1 55  ? 127.800 100.620 100.176 1.00 42.55  ?  55  GLU C C     1 
ATOM 2427 O O     . GLU B 1 55  ? 128.138 100.835 99.007  1.00 42.55  ?  55  GLU C O     1 
ATOM 2428 C CB    . GLU B 1 55  ? 125.882 99.013  100.263 1.00 42.55  ?  55  GLU C CB    1 
ATOM 2429 C CG    . GLU B 1 55  ? 125.491 97.555  100.084 1.00 42.55  ?  55  GLU C CG    1 
ATOM 2430 C CD    . GLU B 1 55  ? 125.194 96.859  101.399 1.00 42.55  ?  55  GLU C CD    1 
ATOM 2431 O OE1   . GLU B 1 55  ? 126.069 96.864  102.292 1.00 42.55  ?  55  GLU C OE1   1 
ATOM 2432 O OE2   . GLU B 1 55  ? 124.084 96.305  101.541 1.00 42.55  -1 55  GLU C OE2   1 
ATOM 2433 N N     . GLY B 1 56  ? 127.796 101.578 101.103 1.00 42.06  ?  56  GLY C N     1 
ATOM 2434 C CA    . GLY B 1 56  ? 128.205 102.928 100.756 1.00 42.06  ?  56  GLY C CA    1 
ATOM 2435 C C     . GLY B 1 56  ? 129.679 103.031 100.414 1.00 42.06  ?  56  GLY C C     1 
ATOM 2436 O O     . GLY B 1 56  ? 130.066 103.794 99.524  1.00 42.06  ?  56  GLY C O     1 
ATOM 2437 N N     . PHE B 1 57  ? 130.521 102.283 101.121 1.00 42.97  ?  57  PHE C N     1 
ATOM 2438 C CA    . PHE B 1 57  ? 131.946 102.282 100.825 1.00 42.97  ?  57  PHE C CA    1 
ATOM 2439 C C     . PHE B 1 57  ? 132.197 101.735 99.427  1.00 42.97  ?  57  PHE C C     1 
ATOM 2440 O O     . PHE B 1 57  ? 131.591 100.743 99.012  1.00 42.97  ?  57  PHE C O     1 
ATOM 2441 C CB    . PHE B 1 57  ? 132.702 101.446 101.854 1.00 42.97  ?  57  PHE C CB    1 
ATOM 2442 C CG    . PHE B 1 57  ? 132.758 102.068 103.215 1.00 42.97  ?  57  PHE C CG    1 
ATOM 2443 C CD1   . PHE B 1 57  ? 133.632 103.104 103.481 1.00 42.97  ?  57  PHE C CD1   1 
ATOM 2444 C CD2   . PHE B 1 57  ? 131.940 101.613 104.230 1.00 42.97  ?  57  PHE C CD2   1 
ATOM 2445 C CE1   . PHE B 1 57  ? 133.689 103.677 104.733 1.00 42.97  ?  57  PHE C CE1   1 
ATOM 2446 C CE2   . PHE B 1 57  ? 131.993 102.182 105.484 1.00 42.97  ?  57  PHE C CE2   1 
ATOM 2447 C CZ    . PHE B 1 57  ? 132.868 103.215 105.735 1.00 42.97  ?  57  PHE C CZ    1 
ATOM 2448 N N     . ASP B 1 58  ? 133.095 102.395 98.693  1.00 45.25  ?  58  ASP C N     1 
ATOM 2449 C CA    . ASP B 1 58  ? 133.415 101.940 97.345  1.00 45.25  ?  58  ASP C CA    1 
ATOM 2450 C C     . ASP B 1 58  ? 134.070 100.565 97.368  1.00 45.25  ?  58  ASP C C     1 
ATOM 2451 O O     . ASP B 1 58  ? 133.756 99.705  96.538  1.00 45.25  ?  58  ASP C O     1 
ATOM 2452 C CB    . ASP B 1 58  ? 134.318 102.955 96.648  1.00 45.25  ?  58  ASP C CB    1 
ATOM 2453 C CG    . ASP B 1 58  ? 134.312 102.798 95.141  1.00 45.25  ?  58  ASP C CG    1 
ATOM 2454 O OD1   . ASP B 1 58  ? 134.861 101.792 94.644  1.00 45.25  ?  58  ASP C OD1   1 
ATOM 2455 O OD2   . ASP B 1 58  ? 133.758 103.681 94.453  1.00 45.25  -1 58  ASP C OD2   1 
ATOM 2456 N N     . THR B 1 59  ? 134.985 100.341 98.308  1.00 43.58  ?  59  THR C N     1 
ATOM 2457 C CA    . THR B 1 59  ? 135.633 99.047  98.466  1.00 43.58  ?  59  THR C CA    1 
ATOM 2458 C C     . THR B 1 59  ? 135.744 98.730  99.948  1.00 43.58  ?  59  THR C C     1 
ATOM 2459 O O     . THR B 1 59  ? 136.207 99.565  100.731 1.00 43.58  ?  59  THR C O     1 
ATOM 2460 C CB    . THR B 1 59  ? 137.020 99.031  97.816  1.00 43.58  ?  59  THR C CB    1 
ATOM 2461 O OG1   . THR B 1 59  ? 136.937 99.592  96.501  1.00 43.58  ?  59  THR C OG1   1 
ATOM 2462 C CG2   . THR B 1 59  ? 137.544 97.608  97.722  1.00 43.58  ?  59  THR C CG2   1 
ATOM 2463 N N     . TYR B 1 60  ? 135.324 97.528  100.326 1.00 42.98  ?  60  TYR C N     1 
ATOM 2464 C CA    . TYR B 1 60  ? 135.315 97.099  101.715 1.00 42.98  ?  60  TYR C CA    1 
ATOM 2465 C C     . TYR B 1 60  ? 135.864 95.686  101.816 1.00 42.98  ?  60  TYR C C     1 
ATOM 2466 O O     . TYR B 1 60  ? 135.588 94.842  100.960 1.00 42.98  ?  60  TYR C O     1 
ATOM 2467 C CB    . TYR B 1 60  ? 133.901 97.151  102.299 1.00 42.98  ?  60  TYR C CB    1 
ATOM 2468 C CG    . TYR B 1 60  ? 133.854 97.308  103.799 1.00 42.98  ?  60  TYR C CG    1 
ATOM 2469 C CD1   . TYR B 1 60  ? 133.798 98.564  104.383 1.00 42.98  ?  60  TYR C CD1   1 
ATOM 2470 C CD2   . TYR B 1 60  ? 133.859 96.200  104.632 1.00 42.98  ?  60  TYR C CD2   1 
ATOM 2471 C CE1   . TYR B 1 60  ? 133.752 98.711  105.751 1.00 42.98  ?  60  TYR C CE1   1 
ATOM 2472 C CE2   . TYR B 1 60  ? 133.814 96.338  106.001 1.00 42.98  ?  60  TYR C CE2   1 
ATOM 2473 C CZ    . TYR B 1 60  ? 133.760 97.596  106.555 1.00 42.98  ?  60  TYR C CZ    1 
ATOM 2474 O OH    . TYR B 1 60  ? 133.714 97.739  107.920 1.00 42.98  ?  60  TYR C OH    1 
ATOM 2475 N N     . ARG B 1 61  ? 136.642 95.435  102.866 1.00 55.39  ?  61  ARG C N     1 
ATOM 2476 C CA    . ARG B 1 61  ? 137.158 94.094  103.126 1.00 55.39  ?  61  ARG C CA    1 
ATOM 2477 C C     . ARG B 1 61  ? 137.577 94.030  104.585 1.00 55.39  ?  61  ARG C C     1 
ATOM 2478 O O     . ARG B 1 61  ? 138.370 94.862  105.037 1.00 55.39  ?  61  ARG C O     1 
ATOM 2479 C CB    . ARG B 1 61  ? 138.329 93.766  102.199 1.00 55.39  ?  61  ARG C CB    1 
ATOM 2480 C CG    . ARG B 1 61  ? 139.413 92.912  102.826 1.00 55.39  ?  61  ARG C CG    1 
ATOM 2481 C CD    . ARG B 1 61  ? 140.324 92.322  101.761 1.00 55.39  ?  61  ARG C CD    1 
ATOM 2482 N NE    . ARG B 1 61  ? 141.152 91.242  102.283 1.00 55.39  ?  61  ARG C NE    1 
ATOM 2483 C CZ    . ARG B 1 61  ? 142.173 91.412  103.111 1.00 55.39  ?  61  ARG C CZ    1 
ATOM 2484 N NH1   . ARG B 1 61  ? 142.541 92.615  103.517 1.00 55.39  1  61  ARG C NH1   1 
ATOM 2485 N NH2   . ARG B 1 61  ? 142.846 90.347  103.537 1.00 55.39  ?  61  ARG C NH2   1 
ATOM 2486 N N     . CYS B 1 62  ? 137.039 93.059  105.320 1.00 56.32  ?  62  CYS C N     1 
ATOM 2487 C CA    . CYS B 1 62  ? 137.291 92.931  106.753 1.00 56.32  ?  62  CYS C CA    1 
ATOM 2488 C C     . CYS B 1 62  ? 137.321 91.450  107.100 1.00 56.32  ?  62  CYS C C     1 
ATOM 2489 O O     . CYS B 1 62  ? 136.285 90.781  107.059 1.00 56.32  ?  62  CYS C O     1 
ATOM 2490 C CB    . CYS B 1 62  ? 136.224 93.662  107.564 1.00 56.32  ?  62  CYS C CB    1 
ATOM 2491 S SG    . CYS B 1 62  ? 136.381 93.465  109.345 1.00 56.32  ?  62  CYS C SG    1 
ATOM 2492 N N     . ASP B 1 63  ? 138.506 90.942  107.441 1.00 63.73  ?  63  ASP C N     1 
ATOM 2493 C CA    . ASP B 1 63  ? 138.653 89.515  107.710 1.00 63.73  ?  63  ASP C CA    1 
ATOM 2494 C C     . ASP B 1 63  ? 138.003 89.127  109.033 1.00 63.73  ?  63  ASP C C     1 
ATOM 2495 O O     . ASP B 1 63  ? 137.271 88.133  109.108 1.00 63.73  ?  63  ASP C O     1 
ATOM 2496 C CB    . ASP B 1 63  ? 140.133 89.135  107.709 1.00 63.73  ?  63  ASP C CB    1 
ATOM 2497 C CG    . ASP B 1 63  ? 140.792 89.374  106.367 1.00 63.73  ?  63  ASP C CG    1 
ATOM 2498 O OD1   . ASP B 1 63  ? 140.089 89.299  105.338 1.00 63.73  ?  63  ASP C OD1   1 
ATOM 2499 O OD2   . ASP B 1 63  ? 142.012 89.641  106.341 1.00 63.73  -1 63  ASP C OD2   1 
ATOM 2500 N N     . ARG B 1 64  ? 138.259 89.897  110.087 1.00 58.51  ?  64  ARG C N     1 
ATOM 2501 C CA    . ARG B 1 64  ? 137.795 89.567  111.425 1.00 58.51  ?  64  ARG C CA    1 
ATOM 2502 C C     . ARG B 1 64  ? 137.212 90.804  112.089 1.00 58.51  ?  64  ARG C C     1 
ATOM 2503 O O     . ARG B 1 64  ? 137.559 91.938  111.752 1.00 58.51  ?  64  ARG C O     1 
ATOM 2504 C CB    . ARG B 1 64  ? 138.929 89.007  112.293 1.00 58.51  ?  64  ARG C CB    1 
ATOM 2505 C CG    . ARG B 1 64  ? 139.645 87.806  111.701 1.00 58.51  ?  64  ARG C CG    1 
ATOM 2506 C CD    . ARG B 1 64  ? 140.887 87.454  112.506 1.00 58.51  ?  64  ARG C CD    1 
ATOM 2507 N NE    . ARG B 1 64  ? 141.830 88.564  112.574 1.00 58.51  ?  64  ARG C NE    1 
ATOM 2508 C CZ    . ARG B 1 64  ? 142.011 89.331  113.641 1.00 58.51  ?  64  ARG C CZ    1 
ATOM 2509 N NH1   . ARG B 1 64  ? 141.323 89.139  114.754 1.00 58.51  1  64  ARG C NH1   1 
ATOM 2510 N NH2   . ARG B 1 64  ? 142.901 90.317  113.587 1.00 58.51  ?  64  ARG C NH2   1 
ATOM 2511 N N     . ASN B 1 65  ? 136.320 90.573  113.048 1.00 47.07  ?  65  ASN C N     1 
ATOM 2512 C CA    . ASN B 1 65  ? 135.745 91.671  113.810 1.00 47.07  ?  65  ASN C CA    1 
ATOM 2513 C C     . ASN B 1 65  ? 136.813 92.308  114.689 1.00 47.07  ?  65  ASN C C     1 
ATOM 2514 O O     . ASN B 1 65  ? 137.565 91.610  115.375 1.00 47.07  ?  65  ASN C O     1 
ATOM 2515 C CB    . ASN B 1 65  ? 134.582 91.172  114.662 1.00 47.07  ?  65  ASN C CB    1 
ATOM 2516 C CG    . ASN B 1 65  ? 133.699 90.193  113.919 1.00 47.07  ?  65  ASN C CG    1 
ATOM 2517 O OD1   . ASN B 1 65  ? 133.709 90.142  112.689 1.00 47.07  ?  65  ASN C OD1   1 
ATOM 2518 N ND2   . ASN B 1 65  ? 132.928 89.407  114.661 1.00 47.07  ?  65  ASN C ND2   1 
ATOM 2519 N N     . LEU B 1 66  ? 136.879 93.635  114.669 1.00 40.72  ?  66  LEU C N     1 
ATOM 2520 C CA    . LEU B 1 66  ? 137.899 94.376  115.392 1.00 40.72  ?  66  LEU C CA    1 
ATOM 2521 C C     . LEU B 1 66  ? 137.246 95.428  116.273 1.00 40.72  ?  66  LEU C C     1 
ATOM 2522 O O     . LEU B 1 66  ? 136.117 95.859  116.033 1.00 40.72  ?  66  LEU C O     1 
ATOM 2523 C CB    . LEU B 1 66  ? 138.894 95.049  114.436 1.00 40.72  ?  66  LEU C CB    1 
ATOM 2524 C CG    . LEU B 1 66  ? 139.296 94.267  113.186 1.00 40.72  ?  66  LEU C CG    1 
ATOM 2525 C CD1   . LEU B 1 66  ? 140.143 95.126  112.267 1.00 40.72  ?  66  LEU C CD1   1 
ATOM 2526 C CD2   . LEU B 1 66  ? 140.042 93.002  113.567 1.00 40.72  ?  66  LEU C CD2   1 
ATOM 2527 N N     . ALA B 1 67  ? 137.976 95.832  117.309 1.00 40.47  ?  67  ALA C N     1 
ATOM 2528 C CA    . ALA B 1 67  ? 137.558 96.918  118.186 1.00 40.47  ?  67  ALA C CA    1 
ATOM 2529 C C     . ALA B 1 67  ? 138.748 97.839  118.389 1.00 40.47  ?  67  ALA C C     1 
ATOM 2530 O O     . ALA B 1 67  ? 139.817 97.386  118.806 1.00 40.47  ?  67  ALA C O     1 
ATOM 2531 C CB    . ALA B 1 67  ? 137.045 96.390  119.528 1.00 40.47  ?  67  ALA C CB    1 
ATOM 2532 N N     . MET B 1 68  ? 138.566 99.121  118.093 1.00 43.91  ?  68  MET C N     1 
ATOM 2533 C CA    . MET B 1 68  ? 139.644 100.096 118.145 1.00 43.91  ?  68  MET C CA    1 
ATOM 2534 C C     . MET B 1 68  ? 139.274 101.239 119.075 1.00 43.91  ?  68  MET C C     1 
ATOM 2535 O O     . MET B 1 68  ? 138.137 101.720 119.063 1.00 43.91  ?  68  MET C O     1 
ATOM 2536 C CB    . MET B 1 68  ? 139.953 100.649 116.753 1.00 43.91  ?  68  MET C CB    1 
ATOM 2537 C CG    . MET B 1 68  ? 139.866 99.620  115.646 1.00 43.91  ?  68  MET C CG    1 
ATOM 2538 S SD    . MET B 1 68  ? 140.644 100.182 114.124 1.00 43.91  ?  68  MET C SD    1 
ATOM 2539 C CE    . MET B 1 68  ? 140.695 98.653  113.199 1.00 43.91  ?  68  MET C CE    1 
ATOM 2540 N N     . GLY B 1 69  ? 140.237 101.667 119.884 1.00 52.14  ?  69  GLY C N     1 
ATOM 2541 C CA    . GLY B 1 69  ? 140.074 102.863 120.682 1.00 52.14  ?  69  GLY C CA    1 
ATOM 2542 C C     . GLY B 1 69  ? 140.884 104.003 120.105 1.00 52.14  ?  69  GLY C C     1 
ATOM 2543 O O     . GLY B 1 69  ? 142.109 104.034 120.249 1.00 52.14  ?  69  GLY C O     1 
ATOM 2544 N N     . VAL B 1 70  ? 140.215 104.945 119.448 1.00 41.30  ?  70  VAL C N     1 
ATOM 2545 C CA    . VAL B 1 70  ? 140.875 106.014 118.709 1.00 41.30  ?  70  VAL C CA    1 
ATOM 2546 C C     . VAL B 1 70  ? 140.539 107.343 119.365 1.00 41.30  ?  70  VAL C C     1 
ATOM 2547 O O     . VAL B 1 70  ? 139.367 107.628 119.636 1.00 41.30  ?  70  VAL C O     1 
ATOM 2548 C CB    . VAL B 1 70  ? 140.456 106.017 117.229 1.00 41.30  ?  70  VAL C CB    1 
ATOM 2549 C CG1   . VAL B 1 70  ? 141.371 106.920 116.426 1.00 41.30  ?  70  VAL C CG1   1 
ATOM 2550 C CG2   . VAL B 1 70  ? 140.476 104.605 116.677 1.00 41.30  ?  70  VAL C CG2   1 
ATOM 2551 N N     . ASN B 1 71  ? 141.566 108.150 119.619 1.00 42.20  ?  71  ASN C N     1 
ATOM 2552 C CA    . ASN B 1 71  ? 141.361 109.479 120.176 1.00 42.20  ?  71  ASN C CA    1 
ATOM 2553 C C     . ASN B 1 71  ? 140.600 110.337 119.174 1.00 42.20  ?  71  ASN C C     1 
ATOM 2554 O O     . ASN B 1 71  ? 141.118 110.653 118.098 1.00 42.20  ?  71  ASN C O     1 
ATOM 2555 C CB    . ASN B 1 71  ? 142.701 110.117 120.526 1.00 42.20  ?  71  ASN C CB    1 
ATOM 2556 C CG    . ASN B 1 71  ? 142.553 111.347 121.400 1.00 42.20  ?  71  ASN C CG    1 
ATOM 2557 O OD1   . ASN B 1 71  ? 141.684 112.188 121.171 1.00 42.20  ?  71  ASN C OD1   1 
ATOM 2558 N ND2   . ASN B 1 71  ? 143.404 111.457 122.412 1.00 42.20  ?  71  ASN C ND2   1 
ATOM 2559 N N     . LEU B 1 72  ? 139.372 110.715 119.531 1.00 38.90  ?  72  LEU C N     1 
ATOM 2560 C CA    . LEU B 1 72  ? 138.519 111.443 118.597 1.00 38.90  ?  72  LEU C CA    1 
ATOM 2561 C C     . LEU B 1 72  ? 139.091 112.813 118.265 1.00 38.90  ?  72  LEU C C     1 
ATOM 2562 O O     . LEU B 1 72  ? 138.979 113.275 117.124 1.00 38.90  ?  72  LEU C O     1 
ATOM 2563 C CB    . LEU B 1 72  ? 137.109 111.570 119.166 1.00 38.90  ?  72  LEU C CB    1 
ATOM 2564 C CG    . LEU B 1 72  ? 136.101 110.624 118.523 1.00 38.90  ?  72  LEU C CG    1 
ATOM 2565 C CD1   . LEU B 1 72  ? 135.957 110.944 117.058 1.00 38.90  ?  72  LEU C CD1   1 
ATOM 2566 C CD2   . LEU B 1 72  ? 136.561 109.196 118.696 1.00 38.90  ?  72  LEU C CD2   1 
ATOM 2567 N N     . THR B 1 73  ? 139.693 113.486 119.246 1.00 39.88  ?  73  THR C N     1 
ATOM 2568 C CA    . THR B 1 73  ? 140.298 114.785 118.974 1.00 39.88  ?  73  THR C CA    1 
ATOM 2569 C C     . THR B 1 73  ? 141.441 114.661 117.974 1.00 39.88  ?  73  THR C C     1 
ATOM 2570 O O     . THR B 1 73  ? 141.560 115.475 117.051 1.00 39.88  ?  73  THR C O     1 
ATOM 2571 C CB    . THR B 1 73  ? 140.791 115.419 120.273 1.00 39.88  ?  73  THR C CB    1 
ATOM 2572 O OG1   . THR B 1 73  ? 139.734 115.406 121.240 1.00 39.88  ?  73  THR C OG1   1 
ATOM 2573 C CG2   . THR B 1 73  ? 141.228 116.853 120.029 1.00 39.88  ?  73  THR C CG2   1 
ATOM 2574 N N     . SER B 1 74  ? 142.287 113.642 118.139 1.00 41.82  ?  74  SER C N     1 
ATOM 2575 C CA    . SER B 1 74  ? 143.393 113.440 117.210 1.00 41.82  ?  74  SER C CA    1 
ATOM 2576 C C     . SER B 1 74  ? 142.889 113.138 115.805 1.00 41.82  ?  74  SER C C     1 
ATOM 2577 O O     . SER B 1 74  ? 143.413 113.672 114.818 1.00 41.82  ?  74  SER C O     1 
ATOM 2578 C CB    . SER B 1 74  ? 144.287 112.308 117.710 1.00 41.82  ?  74  SER C CB    1 
ATOM 2579 O OG    . SER B 1 74  ? 144.629 112.500 119.070 1.00 41.82  ?  74  SER C OG    1 
ATOM 2580 N N     . MET B 1 75  ? 141.873 112.282 115.695 1.00 37.15  ?  75  MET C N     1 
ATOM 2581 C CA    . MET B 1 75  ? 141.327 111.956 114.384 1.00 37.15  ?  75  MET C CA    1 
ATOM 2582 C C     . MET B 1 75  ? 140.694 113.179 113.737 1.00 37.15  ?  75  MET C C     1 
ATOM 2583 O O     . MET B 1 75  ? 140.821 113.383 112.526 1.00 37.15  ?  75  MET C O     1 
ATOM 2584 C CB    . MET B 1 75  ? 140.314 110.821 114.504 1.00 37.15  ?  75  MET C CB    1 
ATOM 2585 C CG    . MET B 1 75  ? 139.911 110.211 113.178 1.00 37.15  ?  75  MET C CG    1 
ATOM 2586 S SD    . MET B 1 75  ? 139.620 108.440 113.312 1.00 37.15  ?  75  MET C SD    1 
ATOM 2587 C CE    . MET B 1 75  ? 138.561 108.163 111.897 1.00 37.15  ?  75  MET C CE    1 
ATOM 2588 N N     . SER B 1 76  ? 140.007 114.005 114.528 1.00 35.15  ?  76  SER C N     1 
ATOM 2589 C CA    . SER B 1 76  ? 139.434 115.234 113.990 1.00 35.15  ?  76  SER C CA    1 
ATOM 2590 C C     . SER B 1 76  ? 140.521 116.177 113.496 1.00 35.15  ?  76  SER C C     1 
ATOM 2591 O O     . SER B 1 76  ? 140.384 116.791 112.431 1.00 35.15  ?  76  SER C O     1 
ATOM 2592 C CB    . SER B 1 76  ? 138.574 115.919 115.049 1.00 35.15  ?  76  SER C CB    1 
ATOM 2593 O OG    . SER B 1 76  ? 138.251 117.241 114.657 1.00 35.15  ?  76  SER C OG    1 
ATOM 2594 N N     . LYS B 1 77  ? 141.608 116.308 114.259 1.00 36.32  ?  77  LYS C N     1 
ATOM 2595 C CA    . LYS B 1 77  ? 142.712 117.159 113.831 1.00 36.32  ?  77  LYS C CA    1 
ATOM 2596 C C     . LYS B 1 77  ? 143.323 116.653 112.532 1.00 36.32  ?  77  LYS C C     1 
ATOM 2597 O O     . LYS B 1 77  ? 143.653 117.446 111.642 1.00 36.32  ?  77  LYS C O     1 
ATOM 2598 C CB    . LYS B 1 77  ? 143.774 117.235 114.926 1.00 36.32  ?  77  LYS C CB    1 
ATOM 2599 C CG    . LYS B 1 77  ? 143.330 117.981 116.168 1.00 36.32  ?  77  LYS C CG    1 
ATOM 2600 C CD    . LYS B 1 77  ? 143.229 119.471 115.906 1.00 36.32  ?  77  LYS C CD    1 
ATOM 2601 C CE    . LYS B 1 77  ? 144.589 120.135 116.021 1.00 36.32  ?  77  LYS C CE    1 
ATOM 2602 N NZ    . LYS B 1 77  ? 145.237 119.833 117.326 1.00 36.32  1  77  LYS C NZ    1 
ATOM 2603 N N     . ILE B 1 78  ? 143.486 115.336 112.406 1.00 33.66  ?  78  ILE C N     1 
ATOM 2604 C CA    . ILE B 1 78  ? 144.048 114.776 111.180 1.00 33.66  ?  78  ILE C CA    1 
ATOM 2605 C C     . ILE B 1 78  ? 143.109 115.016 110.003 1.00 33.66  ?  78  ILE C C     1 
ATOM 2606 O O     . ILE B 1 78  ? 143.538 115.434 108.921 1.00 33.66  ?  78  ILE C O     1 
ATOM 2607 C CB    . ILE B 1 78  ? 144.355 113.280 111.365 1.00 33.66  ?  78  ILE C CB    1 
ATOM 2608 C CG1   . ILE B 1 78  ? 145.656 113.100 112.145 1.00 33.66  ?  78  ILE C CG1   1 
ATOM 2609 C CG2   . ILE B 1 78  ? 144.448 112.585 110.021 1.00 33.66  ?  78  ILE C CG2   1 
ATOM 2610 C CD1   . ILE B 1 78  ? 146.121 111.666 112.230 1.00 33.66  ?  78  ILE C CD1   1 
ATOM 2611 N N     . LEU B 1 79  ? 141.811 114.765 110.197 1.00 32.73  ?  79  LEU C N     1 
ATOM 2612 C CA    . LEU B 1 79  ? 140.839 114.935 109.122 1.00 32.73  ?  79  LEU C CA    1 
ATOM 2613 C C     . LEU B 1 79  ? 140.697 116.384 108.682 1.00 32.73  ?  79  LEU C C     1 
ATOM 2614 O O     . LEU B 1 79  ? 140.443 116.634 107.499 1.00 32.73  ?  79  LEU C O     1 
ATOM 2615 C CB    . LEU B 1 79  ? 139.475 114.395 109.548 1.00 32.73  ?  79  LEU C CB    1 
ATOM 2616 C CG    . LEU B 1 79  ? 139.131 112.971 109.113 1.00 32.73  ?  79  LEU C CG    1 
ATOM 2617 C CD1   . LEU B 1 79  ? 139.266 112.838 107.611 1.00 32.73  ?  79  LEU C CD1   1 
ATOM 2618 C CD2   . LEU B 1 79  ? 140.004 111.957 109.816 1.00 32.73  ?  79  LEU C CD2   1 
ATOM 2619 N N     . LYS B 1 80  ? 140.843 117.340 109.601 1.00 38.39  ?  80  LYS C N     1 
ATOM 2620 C CA    . LYS B 1 80  ? 140.747 118.744 109.220 1.00 38.39  ?  80  LYS C CA    1 
ATOM 2621 C C     . LYS B 1 80  ? 141.822 119.122 108.208 1.00 38.39  ?  80  LYS C C     1 
ATOM 2622 O O     . LYS B 1 80  ? 141.604 120.003 107.369 1.00 38.39  ?  80  LYS C O     1 
ATOM 2623 C CB    . LYS B 1 80  ? 140.837 119.624 110.468 1.00 38.39  ?  80  LYS C CB    1 
ATOM 2624 C CG    . LYS B 1 80  ? 141.130 121.089 110.203 1.00 38.39  ?  80  LYS C CG    1 
ATOM 2625 C CD    . LYS B 1 80  ? 142.102 121.641 111.229 1.00 38.39  ?  80  LYS C CD    1 
ATOM 2626 C CE    . LYS B 1 80  ? 143.456 120.960 111.125 1.00 38.39  ?  80  LYS C CE    1 
ATOM 2627 N NZ    . LYS B 1 80  ? 143.996 121.009 109.739 1.00 38.39  1  80  LYS C NZ    1 
ATOM 2628 N N     . CYS B 1 81  ? 142.974 118.450 108.250 1.00 41.68  ?  81  CYS C N     1 
ATOM 2629 C CA    . CYS B 1 81  ? 144.061 118.743 107.325 1.00 41.68  ?  81  CYS C CA    1 
ATOM 2630 C C     . CYS B 1 81  ? 143.761 118.315 105.894 1.00 41.68  ?  81  CYS C C     1 
ATOM 2631 O O     . CYS B 1 81  ? 144.506 118.699 104.986 1.00 41.68  ?  81  CYS C O     1 
ATOM 2632 C CB    . CYS B 1 81  ? 145.349 118.067 107.800 1.00 41.68  ?  81  CYS C CB    1 
ATOM 2633 S SG    . CYS B 1 81  ? 145.867 118.520 109.470 1.00 41.68  ?  81  CYS C SG    1 
ATOM 2634 N N     . ALA B 1 82  ? 142.704 117.542 105.666 1.00 44.54  ?  82  ALA C N     1 
ATOM 2635 C CA    . ALA B 1 82  ? 142.377 117.041 104.339 1.00 44.54  ?  82  ALA C CA    1 
ATOM 2636 C C     . ALA B 1 82  ? 141.310 117.910 103.690 1.00 44.54  ?  82  ALA C C     1 
ATOM 2637 O O     . ALA B 1 82  ? 140.413 118.421 104.367 1.00 44.54  ?  82  ALA C O     1 
ATOM 2638 C CB    . ALA B 1 82  ? 141.892 115.592 104.407 1.00 44.54  ?  82  ALA C CB    1 
ATOM 2639 N N     . GLY B 1 83  ? 141.412 118.071 102.375 1.00 56.62  ?  83  GLY C N     1 
ATOM 2640 C CA    . GLY B 1 83  ? 140.441 118.852 101.640 1.00 56.62  ?  83  GLY C CA    1 
ATOM 2641 C C     . GLY B 1 83  ? 139.114 118.131 101.495 1.00 56.62  ?  83  GLY C C     1 
ATOM 2642 O O     . GLY B 1 83  ? 138.964 116.951 101.814 1.00 56.62  ?  83  GLY C O     1 
ATOM 2643 N N     . ASN B 1 84  ? 138.125 118.868 100.992 1.00 63.46  ?  84  ASN C N     1 
ATOM 2644 C CA    . ASN B 1 84  ? 136.766 118.364 100.859 1.00 63.46  ?  84  ASN C CA    1 
ATOM 2645 C C     . ASN B 1 84  ? 136.529 117.637 99.540  1.00 63.46  ?  84  ASN C C     1 
ATOM 2646 O O     . ASN B 1 84  ? 135.377 117.521 99.106  1.00 63.46  ?  84  ASN C O     1 
ATOM 2647 C CB    . ASN B 1 84  ? 135.762 119.507 101.016 1.00 63.46  ?  84  ASN C CB    1 
ATOM 2648 C CG    . ASN B 1 84  ? 136.191 120.760 100.285 1.00 63.46  ?  84  ASN C CG    1 
ATOM 2649 O OD1   . ASN B 1 84  ? 137.379 120.976 100.044 1.00 63.46  ?  84  ASN C OD1   1 
ATOM 2650 N ND2   . ASN B 1 84  ? 135.224 121.596 99.926  1.00 63.46  ?  84  ASN C ND2   1 
ATOM 2651 N N     . GLU B 1 85  ? 137.588 117.150 98.892  1.00 62.58  ?  85  GLU C N     1 
ATOM 2652 C CA    . GLU B 1 85  ? 137.428 116.383 97.663  1.00 62.58  ?  85  GLU C CA    1 
ATOM 2653 C C     . GLU B 1 85  ? 138.355 115.175 97.606  1.00 62.58  ?  85  GLU C C     1 
ATOM 2654 O O     . GLU B 1 85  ? 138.437 114.529 96.554  1.00 62.58  ?  85  GLU C O     1 
ATOM 2655 C CB    . GLU B 1 85  ? 137.666 117.270 96.435  1.00 62.58  ?  85  GLU C CB    1 
ATOM 2656 C CG    . GLU B 1 85  ? 138.947 118.083 96.496  1.00 62.58  ?  85  GLU C CG    1 
ATOM 2657 C CD    . GLU B 1 85  ? 138.739 119.452 97.109  1.00 62.58  ?  85  GLU C CD    1 
ATOM 2658 O OE1   . GLU B 1 85  ? 137.590 119.766 97.483  1.00 62.58  ?  85  GLU C OE1   1 
ATOM 2659 O OE2   . GLU B 1 85  ? 139.724 120.213 97.217  1.00 62.58  -1 85  GLU C OE2   1 
ATOM 2660 N N     . ASP B 1 86  ? 139.047 114.848 98.693  1.00 50.86  ?  86  ASP C N     1 
ATOM 2661 C CA    . ASP B 1 86  ? 139.999 113.751 98.689  1.00 50.86  ?  86  ASP C CA    1 
ATOM 2662 C C     . ASP B 1 86  ? 139.268 112.413 98.763  1.00 50.86  ?  86  ASP C C     1 
ATOM 2663 O O     . ASP B 1 86  ? 138.038 112.345 98.803  1.00 50.86  ?  86  ASP C O     1 
ATOM 2664 C CB    . ASP B 1 86  ? 140.985 113.909 99.842  1.00 50.86  ?  86  ASP C CB    1 
ATOM 2665 C CG    . ASP B 1 86  ? 141.593 115.294 99.898  1.00 50.86  ?  86  ASP C CG    1 
ATOM 2666 O OD1   . ASP B 1 86  ? 140.852 116.276 99.684  1.00 50.86  ?  86  ASP C OD1   1 
ATOM 2667 O OD2   . ASP B 1 86  ? 142.811 115.403 100.154 1.00 50.86  -1 86  ASP C OD2   1 
ATOM 2668 N N     . ILE B 1 87  ? 140.040 111.332 98.782  1.00 37.30  ?  87  ILE C N     1 
ATOM 2669 C CA    . ILE B 1 87  ? 139.508 109.975 98.813  1.00 37.30  ?  87  ILE C CA    1 
ATOM 2670 C C     . ILE B 1 87  ? 140.106 109.292 100.035 1.00 37.30  ?  87  ILE C C     1 
ATOM 2671 O O     . ILE B 1 87  ? 141.213 108.745 99.973  1.00 37.30  ?  87  ILE C O     1 
ATOM 2672 C CB    . ILE B 1 87  ? 139.823 109.200 97.531  1.00 37.30  ?  87  ILE C CB    1 
ATOM 2673 C CG1   . ILE B 1 87  ? 139.324 109.969 96.308  1.00 37.30  ?  87  ILE C CG1   1 
ATOM 2674 C CG2   . ILE B 1 87  ? 139.200 107.819 97.577  1.00 37.30  ?  87  ILE C CG2   1 
ATOM 2675 C CD1   . ILE B 1 87  ? 139.730 109.349 94.992  1.00 37.30  ?  87  ILE C CD1   1 
ATOM 2676 N N     . ILE B 1 88  ? 139.378 109.320 101.152 1.00 29.65  ?  88  ILE C N     1 
ATOM 2677 C CA    . ILE B 1 88  ? 139.860 108.696 102.377 1.00 29.65  ?  88  ILE C CA    1 
ATOM 2678 C C     . ILE B 1 88  ? 139.950 107.190 102.185 1.00 29.65  ?  88  ILE C C     1 
ATOM 2679 O O     . ILE B 1 88  ? 139.076 106.567 101.567 1.00 29.65  ?  88  ILE C O     1 
ATOM 2680 C CB    . ILE B 1 88  ? 138.942 109.055 103.556 1.00 29.65  ?  88  ILE C CB    1 
ATOM 2681 C CG1   . ILE B 1 88  ? 138.469 110.501 103.433 1.00 29.65  ?  88  ILE C CG1   1 
ATOM 2682 C CG2   . ILE B 1 88  ? 139.667 108.852 104.864 1.00 29.65  ?  88  ILE C CG2   1 
ATOM 2683 C CD1   . ILE B 1 88  ? 139.528 111.520 103.762 1.00 29.65  ?  88  ILE C CD1   1 
ATOM 2684 N N     . THR B 1 89  ? 141.017 106.596 102.710 1.00 29.13  ?  89  THR C N     1 
ATOM 2685 C CA    . THR B 1 89  ? 141.336 105.186 102.504 1.00 29.13  ?  89  THR C CA    1 
ATOM 2686 C C     . THR B 1 89  ? 141.743 104.530 103.818 1.00 29.13  ?  89  THR C C     1 
ATOM 2687 O O     . THR B 1 89  ? 142.813 103.928 103.930 1.00 29.13  ?  89  THR C O     1 
ATOM 2688 C CB    . THR B 1 89  ? 142.432 105.026 101.456 1.00 29.13  ?  89  THR C CB    1 
ATOM 2689 O OG1   . THR B 1 89  ? 142.257 106.012 100.433 1.00 29.13  ?  89  THR C OG1   1 
ATOM 2690 C CG2   . THR B 1 89  ? 142.367 103.644 100.824 1.00 29.13  ?  89  THR C CG2   1 
ATOM 2691 N N     . LEU B 1 90  ? 140.904 104.681 104.845 1.00 30.16  ?  90  LEU C N     1 
ATOM 2692 C CA    . LEU B 1 90  ? 141.166 104.075 106.148 1.00 30.16  ?  90  LEU C CA    1 
ATOM 2693 C C     . LEU B 1 90  ? 141.586 102.620 106.006 1.00 30.16  ?  90  LEU C C     1 
ATOM 2694 O O     . LEU B 1 90  ? 140.938 101.835 105.310 1.00 30.16  ?  90  LEU C O     1 
ATOM 2695 C CB    . LEU B 1 90  ? 139.923 104.163 107.035 1.00 30.16  ?  90  LEU C CB    1 
ATOM 2696 C CG    . LEU B 1 90  ? 139.331 105.531 107.358 1.00 30.16  ?  90  LEU C CG    1 
ATOM 2697 C CD1   . LEU B 1 90  ? 138.519 105.448 108.634 1.00 30.16  ?  90  LEU C CD1   1 
ATOM 2698 C CD2   . LEU B 1 90  ? 140.435 106.549 107.511 1.00 30.16  ?  90  LEU C CD2   1 
ATOM 2699 N N     . ARG B 1 91  ? 142.684 102.268 106.669 1.00 36.95  ?  91  ARG C N     1 
ATOM 2700 C CA    . ARG B 1 91  ? 143.225 100.919 106.606 1.00 36.95  ?  91  ARG C CA    1 
ATOM 2701 C C     . ARG B 1 91  ? 144.009 100.652 107.879 1.00 36.95  ?  91  ARG C C     1 
ATOM 2702 O O     . ARG B 1 91  ? 144.828 101.480 108.287 1.00 36.95  ?  91  ARG C O     1 
ATOM 2703 C CB    . ARG B 1 91  ? 144.122 100.744 105.378 1.00 36.95  ?  91  ARG C CB    1 
ATOM 2704 C CG    . ARG B 1 91  ? 145.069 99.564  105.464 1.00 36.95  ?  91  ARG C CG    1 
ATOM 2705 C CD    . ARG B 1 91  ? 146.255 99.746  104.534 1.00 36.95  ?  91  ARG C CD    1 
ATOM 2706 N NE    . ARG B 1 91  ? 145.874 99.637  103.132 1.00 36.95  ?  91  ARG C NE    1 
ATOM 2707 C CZ    . ARG B 1 91  ? 145.712 100.671 102.317 1.00 36.95  ?  91  ARG C CZ    1 
ATOM 2708 N NH1   . ARG B 1 91  ? 145.889 101.913 102.735 1.00 36.95  1  91  ARG C NH1   1 
ATOM 2709 N NH2   . ARG B 1 91  ? 145.364 100.452 101.053 1.00 36.95  ?  91  ARG C NH2   1 
ATOM 2710 N N     . ALA B 1 92  ? 143.756 99.505  108.502 1.00 55.06  ?  92  ALA C N     1 
ATOM 2711 C CA    . ALA B 1 92  ? 144.434 99.119  109.731 1.00 55.06  ?  92  ALA C CA    1 
ATOM 2712 C C     . ALA B 1 92  ? 144.946 97.696  109.598 1.00 55.06  ?  92  ALA C C     1 
ATOM 2713 O O     . ALA B 1 92  ? 144.195 96.797  109.203 1.00 55.06  ?  92  ALA C O     1 
ATOM 2714 C CB    . ALA B 1 92  ? 143.502 99.235  110.939 1.00 55.06  ?  92  ALA C CB    1 
ATOM 2715 N N     . GLU B 1 93  ? 146.216 97.493  109.928 1.00 80.56  ?  93  GLU C N     1 
ATOM 2716 C CA    . GLU B 1 93  ? 146.797 96.164  109.896 1.00 80.56  ?  93  GLU C CA    1 
ATOM 2717 C C     . GLU B 1 93  ? 146.347 95.360  111.113 1.00 80.56  ?  93  GLU C C     1 
ATOM 2718 O O     . GLU B 1 93  ? 145.830 95.899  112.095 1.00 80.56  ?  93  GLU C O     1 
ATOM 2719 C CB    . GLU B 1 93  ? 148.321 96.244  109.843 1.00 80.56  ?  93  GLU C CB    1 
ATOM 2720 C CG    . GLU B 1 93  ? 148.965 95.159  109.000 1.00 80.56  ?  93  GLU C CG    1 
ATOM 2721 C CD    . GLU B 1 93  ? 148.163 94.842  107.755 1.00 80.56  ?  93  GLU C CD    1 
ATOM 2722 O OE1   . GLU B 1 93  ? 148.254 95.616  106.779 1.00 80.56  ?  93  GLU C OE1   1 
ATOM 2723 O OE2   . GLU B 1 93  ? 147.444 93.821  107.751 1.00 80.56  -1 93  GLU C OE2   1 
ATOM 2724 N N     . ASP B 1 94  ? 146.551 94.049  111.039 1.00 86.83  ?  94  ASP C N     1 
ATOM 2725 C CA    . ASP B 1 94  ? 146.148 93.162  112.122 1.00 86.83  ?  94  ASP C CA    1 
ATOM 2726 C C     . ASP B 1 94  ? 147.027 93.395  113.346 1.00 86.83  ?  94  ASP C C     1 
ATOM 2727 O O     . ASP B 1 94  ? 148.255 93.277  113.267 1.00 86.83  ?  94  ASP C O     1 
ATOM 2728 C CB    . ASP B 1 94  ? 146.226 91.707  111.666 1.00 86.83  ?  94  ASP C CB    1 
ATOM 2729 C CG    . ASP B 1 94  ? 147.550 91.373  111.009 1.00 86.83  ?  94  ASP C CG    1 
ATOM 2730 O OD1   . ASP B 1 94  ? 148.287 92.312  110.641 1.00 86.83  ?  94  ASP C OD1   1 
ATOM 2731 O OD2   . ASP B 1 94  ? 147.854 90.171  110.860 1.00 86.83  -1 94  ASP C OD2   1 
ATOM 2732 N N     . ASN B 1 95  ? 146.387 93.714  114.473 1.00 84.96  ?  95  ASN C N     1 
ATOM 2733 C CA    . ASN B 1 95  ? 147.041 93.972  115.761 1.00 84.96  ?  95  ASN C CA    1 
ATOM 2734 C C     . ASN B 1 95  ? 148.333 94.771  115.592 1.00 84.96  ?  95  ASN C C     1 
ATOM 2735 O O     . ASN B 1 95  ? 149.410 94.375  116.042 1.00 84.96  ?  95  ASN C O     1 
ATOM 2736 C CB    . ASN B 1 95  ? 147.294 92.669  116.526 1.00 84.96  ?  95  ASN C CB    1 
ATOM 2737 C CG    . ASN B 1 95  ? 148.122 91.671  115.740 1.00 84.96  ?  95  ASN C CG    1 
ATOM 2738 O OD1   . ASN B 1 95  ? 147.588 90.876  114.967 1.00 84.96  ?  95  ASN C OD1   1 
ATOM 2739 N ND2   . ASN B 1 95  ? 149.435 91.711  115.932 1.00 84.96  ?  95  ASN C ND2   1 
ATOM 2740 N N     . ALA B 1 96  ? 148.212 95.922  114.932 1.00 71.91  ?  96  ALA C N     1 
ATOM 2741 C CA    . ALA B 1 96  ? 149.351 96.797  114.694 1.00 71.91  ?  96  ALA C CA    1 
ATOM 2742 C C     . ALA B 1 96  ? 149.219 98.161  115.354 1.00 71.91  ?  96  ALA C C     1 
ATOM 2743 O O     . ALA B 1 96  ? 150.188 98.928  115.340 1.00 71.91  ?  96  ALA C O     1 
ATOM 2744 C CB    . ALA B 1 96  ? 149.572 96.986  113.187 1.00 71.91  ?  96  ALA C CB    1 
ATOM 2745 N N     . ASP B 1 97  ? 148.059 98.478  115.932 1.00 71.55  ?  97  ASP C N     1 
ATOM 2746 C CA    . ASP B 1 97  ? 147.831 99.755  116.611 1.00 71.55  ?  97  ASP C CA    1 
ATOM 2747 C C     . ASP B 1 97  ? 148.132 100.937 115.694 1.00 71.55  ?  97  ASP C C     1 
ATOM 2748 O O     . ASP B 1 97  ? 148.738 101.930 116.101 1.00 71.55  ?  97  ASP C O     1 
ATOM 2749 C CB    . ASP B 1 97  ? 148.650 99.847  117.900 1.00 71.55  ?  97  ASP C CB    1 
ATOM 2750 C CG    . ASP B 1 97  ? 148.545 98.597  118.748 1.00 71.55  ?  97  ASP C CG    1 
ATOM 2751 O OD1   . ASP B 1 97  ? 149.010 97.529  118.299 1.00 71.55  ?  97  ASP C OD1   1 
ATOM 2752 O OD2   . ASP B 1 97  ? 147.998 98.682  119.867 1.00 71.55  -1 97  ASP C OD2   1 
ATOM 2753 N N     . THR B 1 98  ? 147.701 100.832 114.438 1.00 55.09  ?  98  THR C N     1 
ATOM 2754 C CA    . THR B 1 98  ? 147.929 101.880 113.450 1.00 55.09  ?  98  THR C CA    1 
ATOM 2755 C C     . THR B 1 98  ? 146.702 102.003 112.564 1.00 55.09  ?  98  THR C C     1 
ATOM 2756 O O     . THR B 1 98  ? 146.291 101.026 111.930 1.00 55.09  ?  98  THR C O     1 
ATOM 2757 C CB    . THR B 1 98  ? 149.170 101.584 112.601 1.00 55.09  ?  98  THR C CB    1 
ATOM 2758 O OG1   . THR B 1 98  ? 149.207 100.190 112.275 1.00 55.09  ?  98  THR C OG1   1 
ATOM 2759 C CG2   . THR B 1 98  ? 150.438 101.961 113.352 1.00 55.09  ?  98  THR C CG2   1 
ATOM 2760 N N     . LEU B 1 99  ? 146.122 103.199 112.519 1.00 39.46  ?  99  LEU C N     1 
ATOM 2761 C CA    . LEU B 1 99  ? 145.006 103.509 111.627 1.00 39.46  ?  99  LEU C CA    1 
ATOM 2762 C C     . LEU B 1 99  ? 145.566 104.358 110.491 1.00 39.46  ?  99  LEU C C     1 
ATOM 2763 O O     . LEU B 1 99  ? 145.541 105.587 110.538 1.00 39.46  ?  99  LEU C O     1 
ATOM 2764 C CB    . LEU B 1 99  ? 143.892 104.225 112.380 1.00 39.46  ?  99  LEU C CB    1 
ATOM 2765 C CG    . LEU B 1 99  ? 142.500 104.178 111.754 1.00 39.46  ?  99  LEU C CG    1 
ATOM 2766 C CD1   . LEU B 1 99  ? 142.204 102.794 111.206 1.00 39.46  ?  99  LEU C CD1   1 
ATOM 2767 C CD2   . LEU B 1 99  ? 141.452 104.587 112.770 1.00 39.46  ?  99  LEU C CD2   1 
ATOM 2768 N N     . ALA B 1 100 ? 146.074 103.691 109.458 1.00 30.99  ?  100 ALA C N     1 
ATOM 2769 C CA    . ALA B 1 100 ? 146.817 104.357 108.388 1.00 30.99  ?  100 ALA C CA    1 
ATOM 2770 C C     . ALA B 1 100 ? 145.846 105.066 107.454 1.00 30.99  ?  100 ALA C C     1 
ATOM 2771 O O     . ALA B 1 100 ? 145.340 104.489 106.492 1.00 30.99  ?  100 ALA C O     1 
ATOM 2772 C CB    . ALA B 1 100 ? 147.676 103.353 107.631 1.00 30.99  ?  100 ALA C CB    1 
ATOM 2773 N N     . LEU B 1 101 ? 145.585 106.338 107.738 1.00 27.38  ?  101 LEU C N     1 
ATOM 2774 C CA    . LEU B 1 101 ? 144.797 107.154 106.826 1.00 27.38  ?  101 LEU C CA    1 
ATOM 2775 C C     . LEU B 1 101 ? 145.600 107.469 105.572 1.00 27.38  ?  101 LEU C C     1 
ATOM 2776 O O     . LEU B 1 101 ? 146.802 107.734 105.636 1.00 27.38  ?  101 LEU C O     1 
ATOM 2777 C CB    . LEU B 1 101 ? 144.368 108.453 107.502 1.00 27.38  ?  101 LEU C CB    1 
ATOM 2778 C CG    . LEU B 1 101 ? 143.369 108.357 108.650 1.00 27.38  ?  101 LEU C CG    1 
ATOM 2779 C CD1   . LEU B 1 101 ? 144.088 108.394 109.978 1.00 27.38  ?  101 LEU C CD1   1 
ATOM 2780 C CD2   . LEU B 1 101 ? 142.368 109.486 108.560 1.00 27.38  ?  101 LEU C CD2   1 
ATOM 2781 N N     . VAL B 1 102 ? 144.931 107.436 104.424 1.00 19.93  ?  102 VAL C N     1 
ATOM 2782 C CA    . VAL B 1 102 ? 145.538 107.797 103.149 1.00 19.93  ?  102 VAL C CA    1 
ATOM 2783 C C     . VAL B 1 102 ? 144.568 108.704 102.409 1.00 19.93  ?  102 VAL C C     1 
ATOM 2784 O O     . VAL B 1 102 ? 143.421 108.316 102.161 1.00 19.93  ?  102 VAL C O     1 
ATOM 2785 C CB    . VAL B 1 102 ? 145.879 106.562 102.300 1.00 19.93  ?  102 VAL C CB    1 
ATOM 2786 C CG1   . VAL B 1 102 ? 146.106 106.961 100.853 1.00 19.93  ?  102 VAL C CG1   1 
ATOM 2787 C CG2   . VAL B 1 102 ? 147.100 105.857 102.859 1.00 19.93  ?  102 VAL C CG2   1 
ATOM 2788 N N     . PHE B 1 103 ? 145.021 109.904 102.058 1.00 33.69  ?  103 PHE C N     1 
ATOM 2789 C CA    . PHE B 1 103 ? 144.221 110.856 101.298 1.00 33.69  ?  103 PHE C CA    1 
ATOM 2790 C C     . PHE B 1 103 ? 144.827 111.003 99.911  1.00 33.69  ?  103 PHE C C     1 
ATOM 2791 O O     . PHE B 1 103 ? 145.995 111.381 99.778  1.00 33.69  ?  103 PHE C O     1 
ATOM 2792 C CB    . PHE B 1 103 ? 144.157 112.221 101.985 1.00 33.69  ?  103 PHE C CB    1 
ATOM 2793 C CG    . PHE B 1 103 ? 143.876 112.161 103.458 1.00 33.69  ?  103 PHE C CG    1 
ATOM 2794 C CD1   . PHE B 1 103 ? 143.073 111.173 103.994 1.00 33.69  ?  103 PHE C CD1   1 
ATOM 2795 C CD2   . PHE B 1 103 ? 144.408 113.112 104.308 1.00 33.69  ?  103 PHE C CD2   1 
ATOM 2796 C CE1   . PHE B 1 103 ? 142.819 111.128 105.346 1.00 33.69  ?  103 PHE C CE1   1 
ATOM 2797 C CE2   . PHE B 1 103 ? 144.154 113.072 105.660 1.00 33.69  ?  103 PHE C CE2   1 
ATOM 2798 C CZ    . PHE B 1 103 ? 143.359 112.080 106.180 1.00 33.69  ?  103 PHE C CZ    1 
ATOM 2799 N N     . GLU B 1 104 ? 144.038 110.710 98.886  1.00 45.15  ?  104 GLU C N     1 
ATOM 2800 C CA    . GLU B 1 104 ? 144.465 110.921 97.513  1.00 45.15  ?  104 GLU C CA    1 
ATOM 2801 C C     . GLU B 1 104 ? 143.980 112.292 97.044  1.00 45.15  ?  104 GLU C C     1 
ATOM 2802 O O     . GLU B 1 104 ? 143.477 113.098 97.830  1.00 45.15  ?  104 GLU C O     1 
ATOM 2803 C CB    . GLU B 1 104 ? 143.961 109.790 96.621  1.00 45.15  ?  104 GLU C CB    1 
ATOM 2804 C CG    . GLU B 1 104 ? 144.935 108.632 96.496  1.00 45.15  ?  104 GLU C CG    1 
ATOM 2805 C CD    . GLU B 1 104 ? 144.254 107.282 96.603  1.00 45.15  ?  104 GLU C CD    1 
ATOM 2806 O OE1   . GLU B 1 104 ? 143.007 107.244 96.634  1.00 45.15  ?  104 GLU C OE1   1 
ATOM 2807 O OE2   . GLU B 1 104 ? 144.968 106.259 96.656  1.00 45.15  -1 104 GLU C OE2   1 
ATOM 2808 N N     . ALA B 1 105 ? 144.133 112.574 95.756  1.00 62.18  ?  105 ALA C N     1 
ATOM 2809 C CA    . ALA B 1 105 ? 143.710 113.846 95.200  1.00 62.18  ?  105 ALA C CA    1 
ATOM 2810 C C     . ALA B 1 105 ? 142.947 113.621 93.904  1.00 62.18  ?  105 ALA C C     1 
ATOM 2811 O O     . ALA B 1 105 ? 143.215 112.657 93.180  1.00 62.18  ?  105 ALA C O     1 
ATOM 2812 C CB    . ALA B 1 105 ? 144.914 114.761 94.937  1.00 62.18  ?  105 ALA C CB    1 
ATOM 2813 N N     . PRO B 1 106 ? 141.984 114.492 93.591  1.00 69.15  ?  106 PRO C N     1 
ATOM 2814 C CA    . PRO B 1 106 ? 141.243 114.341 92.328  1.00 69.15  ?  106 PRO C CA    1 
ATOM 2815 C C     . PRO B 1 106 ? 142.119 114.443 91.093  1.00 69.15  ?  106 PRO C C     1 
ATOM 2816 O O     . PRO B 1 106 ? 141.773 113.861 90.058  1.00 69.15  ?  106 PRO C O     1 
ATOM 2817 C CB    . PRO B 1 106 ? 140.216 115.481 92.381  1.00 69.15  ?  106 PRO C CB    1 
ATOM 2818 C CG    . PRO B 1 106 ? 140.143 115.878 93.820  1.00 69.15  ?  106 PRO C CG    1 
ATOM 2819 C CD    . PRO B 1 106 ? 141.503 115.634 94.383  1.00 69.15  ?  106 PRO C CD    1 
ATOM 2820 N N     . ASN B 1 107 ? 143.237 115.162 91.167  1.00 69.86  ?  107 ASN C N     1 
ATOM 2821 C CA    . ASN B 1 107 ? 144.157 115.312 90.049  1.00 69.86  ?  107 ASN C CA    1 
ATOM 2822 C C     . ASN B 1 107 ? 145.346 114.360 90.135  1.00 69.86  ?  107 ASN C C     1 
ATOM 2823 O O     . ASN B 1 107 ? 146.284 114.489 89.341  1.00 69.86  ?  107 ASN C O     1 
ATOM 2824 C CB    . ASN B 1 107 ? 144.642 116.759 89.962  1.00 69.86  ?  107 ASN C CB    1 
ATOM 2825 C CG    . ASN B 1 107 ? 144.976 117.339 91.319  1.00 69.86  ?  107 ASN C CG    1 
ATOM 2826 O OD1   . ASN B 1 107 ? 145.295 116.608 92.255  1.00 69.86  ?  107 ASN C OD1   1 
ATOM 2827 N ND2   . ASN B 1 107 ? 144.909 118.660 91.433  1.00 69.86  ?  107 ASN C ND2   1 
ATOM 2828 N N     . GLN B 1 108 ? 145.297 113.384 91.053  1.00 68.07  ?  108 GLN C N     1 
ATOM 2829 C CA    . GLN B 1 108 ? 146.378 112.431 91.318  1.00 68.07  ?  108 GLN C CA    1 
ATOM 2830 C C     . GLN B 1 108 ? 147.771 113.027 91.140  1.00 68.07  ?  108 GLN C C     1 
ATOM 2831 O O     . GLN B 1 108 ? 148.565 112.524 90.339  1.00 68.07  ?  108 GLN C O     1 
ATOM 2832 C CB    . GLN B 1 108 ? 146.285 111.114 90.510  1.00 68.07  ?  108 GLN C CB    1 
ATOM 2833 C CG    . GLN B 1 108 ? 146.014 111.086 88.985  1.00 68.07  ?  108 GLN C CG    1 
ATOM 2834 C CD    . GLN B 1 108 ? 144.641 111.579 88.534  1.00 68.07  ?  108 GLN C CD    1 
ATOM 2835 O OE1   . GLN B 1 108 ? 143.968 112.344 89.206  1.00 68.07  ?  108 GLN C OE1   1 
ATOM 2836 N NE2   . GLN B 1 108 ? 144.233 111.129 87.354  1.00 68.07  ?  108 GLN C NE2   1 
ATOM 2837 N N     . GLU B 1 109 ? 148.081 114.094 91.875  1.00 55.41  ?  109 GLU C N     1 
ATOM 2838 C CA    . GLU B 1 109 ? 149.431 114.637 91.897  1.00 55.41  ?  109 GLU C CA    1 
ATOM 2839 C C     . GLU B 1 109 ? 149.963 114.855 93.305  1.00 55.41  ?  109 GLU C C     1 
ATOM 2840 O O     . GLU B 1 109 ? 151.113 115.284 93.457  1.00 55.41  ?  109 GLU C O     1 
ATOM 2841 C CB    . GLU B 1 109 ? 149.498 115.955 91.114  1.00 55.41  ?  109 GLU C CB    1 
ATOM 2842 C CG    . GLU B 1 109 ? 148.330 116.889 91.352  1.00 55.41  ?  109 GLU C CG    1 
ATOM 2843 C CD    . GLU B 1 109 ? 148.479 117.696 92.626  1.00 55.41  ?  109 GLU C CD    1 
ATOM 2844 O OE1   . GLU B 1 109 ? 149.629 117.903 93.066  1.00 55.41  ?  109 GLU C OE1   1 
ATOM 2845 O OE2   . GLU B 1 109 ? 147.450 118.125 93.188  1.00 55.41  -1 109 GLU C OE2   1 
ATOM 2846 N N     . LYS B 1 110 ? 149.170 114.571 94.336  1.00 40.95  ?  110 LYS C N     1 
ATOM 2847 C CA    . LYS B 1 110 ? 149.601 114.767 95.715  1.00 40.95  ?  110 LYS C CA    1 
ATOM 2848 C C     . LYS B 1 110 ? 148.857 113.782 96.600  1.00 40.95  ?  110 LYS C C     1 
ATOM 2849 O O     . LYS B 1 110 ? 147.633 113.867 96.726  1.00 40.95  ?  110 LYS C O     1 
ATOM 2850 C CB    . LYS B 1 110 ? 149.344 116.203 96.172  1.00 40.95  ?  110 LYS C CB    1 
ATOM 2851 C CG    . LYS B 1 110 ? 149.377 116.396 97.676  1.00 40.95  ?  110 LYS C CG    1 
ATOM 2852 C CD    . LYS B 1 110 ? 148.972 117.807 98.052  1.00 40.95  ?  110 LYS C CD    1 
ATOM 2853 C CE    . LYS B 1 110 ? 148.727 117.931 99.542  1.00 40.95  ?  110 LYS C CE    1 
ATOM 2854 N NZ    . LYS B 1 110 ? 148.170 119.263 99.896  1.00 40.95  1  110 LYS C NZ    1 
ATOM 2855 N N     . VAL B 1 111 ? 149.591 112.852 97.203  1.00 31.31  ?  111 VAL C N     1 
ATOM 2856 C CA    . VAL B 1 111 ? 149.017 111.873 98.113  1.00 31.31  ?  111 VAL C CA    1 
ATOM 2857 C C     . VAL B 1 111 ? 149.577 112.127 99.503  1.00 31.31  ?  111 VAL C C     1 
ATOM 2858 O O     . VAL B 1 111 ? 150.674 112.671 99.663  1.00 31.31  ?  111 VAL C O     1 
ATOM 2859 C CB    . VAL B 1 111 ? 149.298 110.423 97.663  1.00 31.31  ?  111 VAL C CB    1 
ATOM 2860 C CG1   . VAL B 1 111 ? 149.047 110.276 96.173  1.00 31.31  ?  111 VAL C CG1   1 
ATOM 2861 C CG2   . VAL B 1 111 ? 150.718 110.016 98.011  1.00 31.31  ?  111 VAL C CG2   1 
ATOM 2862 N N     . SER B 1 112 ? 148.806 111.744 100.515 1.00 28.19  ?  112 SER C N     1 
ATOM 2863 C CA    . SER B 1 112 ? 149.192 111.939 101.904 1.00 28.19  ?  112 SER C CA    1 
ATOM 2864 C C     . SER B 1 112 ? 149.005 110.636 102.658 1.00 28.19  ?  112 SER C C     1 
ATOM 2865 O O     . SER B 1 112 ? 147.929 110.033 102.604 1.00 28.19  ?  112 SER C O     1 
ATOM 2866 C CB    . SER B 1 112 ? 148.367 113.050 102.556 1.00 28.19  ?  112 SER C CB    1 
ATOM 2867 O OG    . SER B 1 112 ? 148.169 114.127 101.659 1.00 28.19  ?  112 SER C OG    1 
ATOM 2868 N N     . ASP B 1 113 ? 150.046 110.206 103.359 1.00 27.50  ?  113 ASP C N     1 
ATOM 2869 C CA    . ASP B 1 113 ? 149.999 109.016 104.193 1.00 27.50  ?  113 ASP C CA    1 
ATOM 2870 C C     . ASP B 1 113 ? 150.140 109.439 105.646 1.00 27.50  ?  113 ASP C C     1 
ATOM 2871 O O     . ASP B 1 113 ? 151.064 110.180 105.993 1.00 27.50  ?  113 ASP C O     1 
ATOM 2872 C CB    . ASP B 1 113 ? 151.107 108.033 103.808 1.00 27.50  ?  113 ASP C CB    1 
ATOM 2873 C CG    . ASP B 1 113 ? 151.235 106.878 104.785 1.00 27.50  ?  113 ASP C CG    1 
ATOM 2874 O OD1   . ASP B 1 113 ? 150.250 106.563 105.483 1.00 27.50  ?  113 ASP C OD1   1 
ATOM 2875 O OD2   . ASP B 1 113 ? 152.328 106.279 104.854 1.00 27.50  -1 113 ASP C OD2   1 
ATOM 2876 N N     . TYR B 1 114 ? 149.226 108.972 106.489 1.00 28.13  ?  114 TYR C N     1 
ATOM 2877 C CA    . TYR B 1 114 ? 149.239 109.294 107.905 1.00 28.13  ?  114 TYR C CA    1 
ATOM 2878 C C     . TYR B 1 114 ? 149.220 108.008 108.715 1.00 28.13  ?  114 TYR C C     1 
ATOM 2879 O O     . TYR B 1 114 ? 148.997 106.917 108.186 1.00 28.13  ?  114 TYR C O     1 
ATOM 2880 C CB    . TYR B 1 114 ? 148.044 110.163 108.305 1.00 28.13  ?  114 TYR C CB    1 
ATOM 2881 C CG    . TYR B 1 114 ? 148.137 111.602 107.866 1.00 28.13  ?  114 TYR C CG    1 
ATOM 2882 C CD1   . TYR B 1 114 ? 148.139 111.942 106.523 1.00 28.13  ?  114 TYR C CD1   1 
ATOM 2883 C CD2   . TYR B 1 114 ? 148.212 112.623 108.799 1.00 28.13  ?  114 TYR C CD2   1 
ATOM 2884 C CE1   . TYR B 1 114 ? 148.218 113.258 106.122 1.00 28.13  ?  114 TYR C CE1   1 
ATOM 2885 C CE2   . TYR B 1 114 ? 148.293 113.941 108.407 1.00 28.13  ?  114 TYR C CE2   1 
ATOM 2886 C CZ    . TYR B 1 114 ? 148.295 114.253 107.069 1.00 28.13  ?  114 TYR C CZ    1 
ATOM 2887 O OH    . TYR B 1 114 ? 148.375 115.568 106.677 1.00 28.13  ?  114 TYR C OH    1 
ATOM 2888 N N     . GLU B 1 115 ? 149.460 108.152 110.013 1.00 39.49  ?  115 GLU C N     1 
ATOM 2889 C CA    . GLU B 1 115 ? 149.362 107.045 110.948 1.00 39.49  ?  115 GLU C CA    1 
ATOM 2890 C C     . GLU B 1 115 ? 148.904 107.580 112.294 1.00 39.49  ?  115 GLU C C     1 
ATOM 2891 O O     . GLU B 1 115 ? 149.170 108.732 112.644 1.00 39.49  ?  115 GLU C O     1 
ATOM 2892 C CB    . GLU B 1 115 ? 150.695 106.305 111.104 1.00 39.49  ?  115 GLU C CB    1 
ATOM 2893 C CG    . GLU B 1 115 ? 150.924 105.215 110.074 1.00 39.49  ?  115 GLU C CG    1 
ATOM 2894 C CD    . GLU B 1 115 ? 151.916 104.172 110.543 1.00 39.49  ?  115 GLU C CD    1 
ATOM 2895 O OE1   . GLU B 1 115 ? 152.273 104.186 111.739 1.00 39.49  ?  115 GLU C OE1   1 
ATOM 2896 O OE2   . GLU B 1 115 ? 152.339 103.337 109.716 1.00 39.49  -1 115 GLU C OE2   1 
ATOM 2897 N N     . MET B 1 116 ? 148.211 106.732 113.046 1.00 47.98  ?  116 MET C N     1 
ATOM 2898 C CA    . MET B 1 116 ? 147.735 107.096 114.369 1.00 47.98  ?  116 MET C CA    1 
ATOM 2899 C C     . MET B 1 116 ? 148.022 105.956 115.330 1.00 47.98  ?  116 MET C C     1 
ATOM 2900 O O     . MET B 1 116 ? 148.146 104.796 114.933 1.00 47.98  ?  116 MET C O     1 
ATOM 2901 C CB    . MET B 1 116 ? 146.237 107.421 114.371 1.00 47.98  ?  116 MET C CB    1 
ATOM 2902 C CG    . MET B 1 116 ? 145.854 108.519 115.348 1.00 47.98  ?  116 MET C CG    1 
ATOM 2903 S SD    . MET B 1 116 ? 144.127 109.016 115.232 1.00 47.98  ?  116 MET C SD    1 
ATOM 2904 C CE    . MET B 1 116 ? 143.725 108.473 113.577 1.00 47.98  ?  116 MET C CE    1 
ATOM 2905 N N     . LYS B 1 117 ? 148.129 106.302 116.607 1.00 57.72  ?  117 LYS C N     1 
ATOM 2906 C CA    . LYS B 1 117 ? 148.388 105.332 117.659 1.00 57.72  ?  117 LYS C CA    1 
ATOM 2907 C C     . LYS B 1 117 ? 147.069 104.967 118.325 1.00 57.72  ?  117 LYS C C     1 
ATOM 2908 O O     . LYS B 1 117 ? 146.391 105.833 118.888 1.00 57.72  ?  117 LYS C O     1 
ATOM 2909 C CB    . LYS B 1 117 ? 149.380 105.887 118.680 1.00 57.72  ?  117 LYS C CB    1 
ATOM 2910 C CG    . LYS B 1 117 ? 150.774 106.109 118.118 1.00 57.72  ?  117 LYS C CG    1 
ATOM 2911 C CD    . LYS B 1 117 ? 151.649 106.882 119.087 1.00 57.72  ?  117 LYS C CD    1 
ATOM 2912 C CE    . LYS B 1 117 ? 153.005 107.190 118.473 1.00 57.72  ?  117 LYS C CE    1 
ATOM 2913 N NZ    . LYS B 1 117 ? 153.815 108.092 119.338 1.00 57.72  1  117 LYS C NZ    1 
ATOM 2914 N N     . LEU B 1 118 ? 146.709 103.690 118.254 1.00 66.06  ?  118 LEU C N     1 
ATOM 2915 C CA    . LEU B 1 118 ? 145.483 103.221 118.874 1.00 66.06  ?  118 LEU C CA    1 
ATOM 2916 C C     . LEU B 1 118 ? 145.636 103.189 120.392 1.00 66.06  ?  118 LEU C C     1 
ATOM 2917 O O     . LEU B 1 118 ? 146.742 103.254 120.936 1.00 66.06  ?  118 LEU C O     1 
ATOM 2918 C CB    . LEU B 1 118 ? 145.115 101.833 118.352 1.00 66.06  ?  118 LEU C CB    1 
ATOM 2919 C CG    . LEU B 1 118 ? 144.257 101.757 117.088 1.00 66.06  ?  118 LEU C CG    1 
ATOM 2920 C CD1   . LEU B 1 118 ? 144.971 102.361 115.891 1.00 66.06  ?  118 LEU C CD1   1 
ATOM 2921 C CD2   . LEU B 1 118 ? 143.875 100.315 116.805 1.00 66.06  ?  118 LEU C CD2   1 
ATOM 2922 N N     . MET B 1 119 ? 144.503 103.091 121.078 1.00 77.03  ?  119 MET C N     1 
ATOM 2923 C CA    . MET B 1 119 ? 144.474 103.058 122.530 1.00 77.03  ?  119 MET C CA    1 
ATOM 2924 C C     . MET B 1 119 ? 143.651 101.866 122.995 1.00 77.03  ?  119 MET C C     1 
ATOM 2925 O O     . MET B 1 119 ? 142.862 101.295 122.237 1.00 77.03  ?  119 MET C O     1 
ATOM 2926 C CB    . MET B 1 119 ? 143.900 104.355 123.112 1.00 77.03  ?  119 MET C CB    1 
ATOM 2927 C CG    . MET B 1 119 ? 144.699 105.598 122.758 1.00 77.03  ?  119 MET C CG    1 
ATOM 2928 S SD    . MET B 1 119 ? 144.058 107.108 123.510 1.00 77.03  ?  119 MET C SD    1 
ATOM 2929 C CE    . MET B 1 119 ? 142.774 106.458 124.576 1.00 77.03  ?  119 MET C CE    1 
ATOM 2930 N N     . ASP B 1 120 ? 143.848 101.493 124.255 1.00 101.57 ?  120 ASP C N     1 
ATOM 2931 C CA    . ASP B 1 120 ? 143.119 100.393 124.871 1.00 101.57 ?  120 ASP C CA    1 
ATOM 2932 C C     . ASP B 1 120 ? 141.972 100.962 125.695 1.00 101.57 ?  120 ASP C C     1 
ATOM 2933 O O     . ASP B 1 120 ? 142.199 101.732 126.634 1.00 101.57 ?  120 ASP C O     1 
ATOM 2934 C CB    . ASP B 1 120 ? 144.042 99.545  125.744 1.00 101.57 ?  120 ASP C CB    1 
ATOM 2935 C CG    . ASP B 1 120 ? 143.490 98.156  125.994 1.00 101.57 ?  120 ASP C CG    1 
ATOM 2936 O OD1   . ASP B 1 120 ? 142.358 97.876  125.547 1.00 101.57 ?  120 ASP C OD1   1 
ATOM 2937 O OD2   . ASP B 1 120 ? 144.189 97.344  126.636 1.00 101.57 -1 120 ASP C OD2   1 
ATOM 2938 N N     . LEU B 1 121 ? 140.748 100.583 125.343 1.00 102.30 ?  121 LEU C N     1 
ATOM 2939 C CA    . LEU B 1 121 ? 139.547 101.079 125.997 1.00 102.30 ?  121 LEU C CA    1 
ATOM 2940 C C     . LEU B 1 121 ? 138.783 99.923  126.622 1.00 102.30 ?  121 LEU C C     1 
ATOM 2941 O O     . LEU B 1 121 ? 138.787 98.805  126.096 1.00 102.30 ?  121 LEU C O     1 
ATOM 2942 C CB    . LEU B 1 121 ? 138.641 101.822 125.007 1.00 102.30 ?  121 LEU C CB    1 
ATOM 2943 C CG    . LEU B 1 121 ? 138.720 103.350 124.974 1.00 102.30 ?  121 LEU C CG    1 
ATOM 2944 C CD1   . LEU B 1 121 ? 137.987 103.946 126.164 1.00 102.30 ?  121 LEU C CD1   1 
ATOM 2945 C CD2   . LEU B 1 121 ? 140.161 103.829 124.936 1.00 102.30 ?  121 LEU C CD2   1 
ATOM 2946 N N     . ASP B 1 122 ? 138.130 100.197 127.749 1.00 104.78 ?  122 ASP C N     1 
ATOM 2947 C CA    . ASP B 1 122 ? 137.267 99.218  128.398 1.00 104.78 ?  122 ASP C CA    1 
ATOM 2948 C C     . ASP B 1 122 ? 135.939 99.180  127.653 1.00 104.78 ?  122 ASP C C     1 
ATOM 2949 O O     . ASP B 1 122 ? 135.081 100.048 127.849 1.00 104.78 ?  122 ASP C O     1 
ATOM 2950 C CB    . ASP B 1 122 ? 137.071 99.571  129.869 1.00 104.78 ?  122 ASP C CB    1 
ATOM 2951 C CG    . ASP B 1 122 ? 136.900 101.060 130.093 1.00 104.78 ?  122 ASP C CG    1 
ATOM 2952 O OD1   . ASP B 1 122 ? 136.958 101.822 129.105 1.00 104.78 ?  122 ASP C OD1   1 
ATOM 2953 O OD2   . ASP B 1 122 ? 136.710 101.470 131.257 1.00 104.78 -1 122 ASP C OD2   1 
ATOM 2954 N N     . VAL B 1 123 ? 135.768 98.176  126.796 1.00 98.59  ?  123 VAL C N     1 
ATOM 2955 C CA    . VAL B 1 123 ? 134.589 98.092  125.941 1.00 98.59  ?  123 VAL C CA    1 
ATOM 2956 C C     . VAL B 1 123 ? 133.382 97.768  126.815 1.00 98.59  ?  123 VAL C C     1 
ATOM 2957 O O     . VAL B 1 123 ? 133.239 96.643  127.302 1.00 98.59  ?  123 VAL C O     1 
ATOM 2958 C CB    . VAL B 1 123 ? 134.771 97.049  124.833 1.00 98.59  ?  123 VAL C CB    1 
ATOM 2959 C CG1   . VAL B 1 123 ? 133.586 97.077  123.880 1.00 98.59  ?  123 VAL C CG1   1 
ATOM 2960 C CG2   . VAL B 1 123 ? 136.072 97.294  124.084 1.00 98.59  ?  123 VAL C CG2   1 
ATOM 2961 N N     . GLU B 1 124 ? 132.512 98.753  127.014 1.00 101.14 ?  124 GLU C N     1 
ATOM 2962 C CA    . GLU B 1 124 ? 131.264 98.572  127.744 1.00 101.14 ?  124 GLU C CA    1 
ATOM 2963 C C     . GLU B 1 124 ? 130.147 98.397  126.722 1.00 101.14 ?  124 GLU C C     1 
ATOM 2964 O O     . GLU B 1 124 ? 129.907 99.285  125.898 1.00 101.14 ?  124 GLU C O     1 
ATOM 2965 C CB    . GLU B 1 124 ? 130.993 99.759  128.665 1.00 101.14 ?  124 GLU C CB    1 
ATOM 2966 C CG    . GLU B 1 124 ? 131.852 99.782  129.917 1.00 101.14 ?  124 GLU C CG    1 
ATOM 2967 C CD    . GLU B 1 124 ? 131.693 101.067 130.707 1.00 101.14 ?  124 GLU C CD    1 
ATOM 2968 O OE1   . GLU B 1 124 ? 131.003 101.986 130.217 1.00 101.14 ?  124 GLU C OE1   1 
ATOM 2969 O OE2   . GLU B 1 124 ? 132.259 101.159 131.816 1.00 101.14 -1 124 GLU C OE2   1 
ATOM 2970 N N     . GLN B 1 125 ? 129.471 97.254  126.773 1.00 90.96  ?  125 GLN C N     1 
ATOM 2971 C CA    . GLN B 1 125 ? 128.428 96.935  125.810 1.00 90.96  ?  125 GLN C CA    1 
ATOM 2972 C C     . GLN B 1 125 ? 127.092 97.374  126.390 1.00 90.96  ?  125 GLN C C     1 
ATOM 2973 O O     . GLN B 1 125 ? 126.744 97.004  127.516 1.00 90.96  ?  125 GLN C O     1 
ATOM 2974 C CB    . GLN B 1 125 ? 128.452 95.434  125.489 1.00 90.96  ?  125 GLN C CB    1 
ATOM 2975 C CG    . GLN B 1 125 ? 127.648 94.923  124.262 1.00 90.96  ?  125 GLN C CG    1 
ATOM 2976 C CD    . GLN B 1 125 ? 126.152 95.229  124.236 1.00 90.96  ?  125 GLN C CD    1 
ATOM 2977 O OE1   . GLN B 1 125 ? 125.527 95.500  125.258 1.00 90.96  ?  125 GLN C OE1   1 
ATOM 2978 N NE2   . GLN B 1 125 ? 125.574 95.185  123.041 1.00 90.96  ?  125 GLN C NE2   1 
ATOM 2979 N N     . LEU B 1 126 ? 126.348 98.160  125.618 1.00 84.34  ?  126 LEU C N     1 
ATOM 2980 C CA    . LEU B 1 126 ? 125.037 98.651  126.017 1.00 84.34  ?  126 LEU C CA    1 
ATOM 2981 C C     . LEU B 1 126 ? 124.012 98.217  124.982 1.00 84.34  ?  126 LEU C C     1 
ATOM 2982 O O     . LEU B 1 126 ? 124.200 98.445  123.783 1.00 84.34  ?  126 LEU C O     1 
ATOM 2983 C CB    . LEU B 1 126 ? 125.028 100.176 126.162 1.00 84.34  ?  126 LEU C CB    1 
ATOM 2984 C CG    . LEU B 1 126 ? 126.238 100.855 126.810 1.00 84.34  ?  126 LEU C CG    1 
ATOM 2985 C CD1   . LEU B 1 126 ? 127.306 101.201 125.779 1.00 84.34  ?  126 LEU C CD1   1 
ATOM 2986 C CD2   . LEU B 1 126 ? 125.807 102.094 127.572 1.00 84.34  ?  126 LEU C CD2   1 
ATOM 2987 N N     . GLY B 1 127 ? 122.932 97.595  125.446 1.00 79.36  ?  127 GLY C N     1 
ATOM 2988 C CA    . GLY B 1 127 ? 121.873 97.168  124.556 1.00 79.36  ?  127 GLY C CA    1 
ATOM 2989 C C     . GLY B 1 127 ? 120.686 98.107  124.581 1.00 79.36  ?  127 GLY C C     1 
ATOM 2990 O O     . GLY B 1 127 ? 119.894 98.091  125.528 1.00 79.36  ?  127 GLY C O     1 
ATOM 2991 N N     . ILE B 1 128 ? 120.551 98.930  123.546 1.00 76.08  ?  128 ILE C N     1 
ATOM 2992 C CA    . ILE B 1 128 ? 119.473 99.911  123.480 1.00 76.08  ?  128 ILE C CA    1 
ATOM 2993 C C     . ILE B 1 128 ? 118.155 99.183  123.251 1.00 76.08  ?  128 ILE C C     1 
ATOM 2994 O O     . ILE B 1 128 ? 118.004 98.476  122.244 1.00 76.08  ?  128 ILE C O     1 
ATOM 2995 C CB    . ILE B 1 128 ? 119.729 100.948 122.378 1.00 76.08  ?  128 ILE C CB    1 
ATOM 2996 C CG1   . ILE B 1 128 ? 121.138 101.523 122.507 1.00 76.08  ?  128 ILE C CG1   1 
ATOM 2997 C CG2   . ILE B 1 128 ? 118.690 102.052 122.441 1.00 76.08  ?  128 ILE C CG2   1 
ATOM 2998 C CD1   . ILE B 1 128 ? 121.642 102.184 121.245 1.00 76.08  ?  128 ILE C CD1   1 
ATOM 2999 N N     . PRO B 1 129 ? 117.175 99.325  124.146 1.00 85.82  ?  129 PRO C N     1 
ATOM 3000 C CA    . PRO B 1 129 ? 115.885 98.648  123.960 1.00 85.82  ?  129 PRO C CA    1 
ATOM 3001 C C     . PRO B 1 129 ? 114.970 99.478  123.071 1.00 85.82  ?  129 PRO C C     1 
ATOM 3002 O O     . PRO B 1 129 ? 114.605 100.604 123.415 1.00 85.82  ?  129 PRO C O     1 
ATOM 3003 C CB    . PRO B 1 129 ? 115.335 98.532  125.387 1.00 85.82  ?  129 PRO C CB    1 
ATOM 3004 C CG    . PRO B 1 129 ? 116.088 99.559  126.201 1.00 85.82  ?  129 PRO C CG    1 
ATOM 3005 C CD    . PRO B 1 129 ? 117.209 100.131 125.377 1.00 85.82  ?  129 PRO C CD    1 
ATOM 3006 N N     . GLU B 1 130 ? 114.602 98.918  121.923 1.00 91.69  ?  130 GLU C N     1 
ATOM 3007 C CA    . GLU B 1 130 ? 113.706 99.606  121.005 1.00 91.69  ?  130 GLU C CA    1 
ATOM 3008 C C     . GLU B 1 130 ? 112.320 99.743  121.621 1.00 91.69  ?  130 GLU C C     1 
ATOM 3009 O O     . GLU B 1 130 ? 111.845 98.851  122.328 1.00 91.69  ?  130 GLU C O     1 
ATOM 3010 C CB    . GLU B 1 130 ? 113.625 98.854  119.678 1.00 91.69  ?  130 GLU C CB    1 
ATOM 3011 C CG    . GLU B 1 130 ? 114.949 98.761  118.931 1.00 91.69  ?  130 GLU C CG    1 
ATOM 3012 C CD    . GLU B 1 130 ? 115.824 97.620  119.418 1.00 91.69  ?  130 GLU C CD    1 
ATOM 3013 O OE1   . GLU B 1 130 ? 115.484 97.000  120.448 1.00 91.69  ?  130 GLU C OE1   1 
ATOM 3014 O OE2   . GLU B 1 130 ? 116.856 97.345  118.770 1.00 91.69  -1 130 GLU C OE2   1 
ATOM 3015 N N     . GLN B 1 131 ? 111.670 100.873 121.350 1.00 80.80  ?  131 GLN C N     1 
ATOM 3016 C CA    . GLN B 1 131 ? 110.370 101.155 121.937 1.00 80.80  ?  131 GLN C CA    1 
ATOM 3017 C C     . GLN B 1 131 ? 109.575 102.046 120.998 1.00 80.80  ?  131 GLN C C     1 
ATOM 3018 O O     . GLN B 1 131 ? 110.128 102.700 120.110 1.00 80.80  ?  131 GLN C O     1 
ATOM 3019 C CB    . GLN B 1 131 ? 110.512 101.818 123.311 1.00 80.80  ?  131 GLN C CB    1 
ATOM 3020 C CG    . GLN B 1 131 ? 111.589 102.885 123.362 1.00 80.80  ?  131 GLN C CG    1 
ATOM 3021 C CD    . GLN B 1 131 ? 112.247 102.982 124.722 1.00 80.80  ?  131 GLN C CD    1 
ATOM 3022 O OE1   . GLN B 1 131 ? 111.584 103.223 125.729 1.00 80.80  ?  131 GLN C OE1   1 
ATOM 3023 N NE2   . GLN B 1 131 ? 113.561 102.795 124.757 1.00 80.80  ?  131 GLN C NE2   1 
ATOM 3024 N N     . GLU B 1 132 ? 108.261 102.057 121.203 1.00 71.74  ?  132 GLU C N     1 
ATOM 3025 C CA    . GLU B 1 132 ? 107.375 102.909 120.425 1.00 71.74  ?  132 GLU C CA    1 
ATOM 3026 C C     . GLU B 1 132 ? 107.467 104.349 120.913 1.00 71.74  ?  132 GLU C C     1 
ATOM 3027 O O     . GLU B 1 132 ? 107.685 104.605 122.101 1.00 71.74  ?  132 GLU C O     1 
ATOM 3028 C CB    . GLU B 1 132 ? 105.934 102.405 120.524 1.00 71.74  ?  132 GLU C CB    1 
ATOM 3029 C CG    . GLU B 1 132 ? 104.958 103.084 119.576 1.00 71.74  ?  132 GLU C CG    1 
ATOM 3030 C CD    . GLU B 1 132 ? 104.273 104.284 120.202 1.00 71.74  ?  132 GLU C CD    1 
ATOM 3031 O OE1   . GLU B 1 132 ? 104.432 104.492 121.423 1.00 71.74  ?  132 GLU C OE1   1 
ATOM 3032 O OE2   . GLU B 1 132 ? 103.575 105.019 119.473 1.00 71.74  -1 132 GLU C OE2   1 
ATOM 3033 N N     . TYR B 1 133 ? 107.301 105.290 119.989 1.00 54.26  ?  133 TYR C N     1 
ATOM 3034 C CA    . TYR B 1 133 ? 107.390 106.712 120.285 1.00 54.26  ?  133 TYR C CA    1 
ATOM 3035 C C     . TYR B 1 133 ? 106.065 107.390 119.967 1.00 54.26  ?  133 TYR C C     1 
ATOM 3036 O O     . TYR B 1 133 ? 105.429 107.088 118.953 1.00 54.26  ?  133 TYR C O     1 
ATOM 3037 C CB    . TYR B 1 133 ? 108.522 107.364 119.491 1.00 54.26  ?  133 TYR C CB    1 
ATOM 3038 C CG    . TYR B 1 133 ? 109.896 106.996 119.993 1.00 54.26  ?  133 TYR C CG    1 
ATOM 3039 C CD1   . TYR B 1 133 ? 110.534 105.849 119.548 1.00 54.26  ?  133 TYR C CD1   1 
ATOM 3040 C CD2   . TYR B 1 133 ? 110.554 107.793 120.915 1.00 54.26  ?  133 TYR C CD2   1 
ATOM 3041 C CE1   . TYR B 1 133 ? 111.788 105.509 120.007 1.00 54.26  ?  133 TYR C CE1   1 
ATOM 3042 C CE2   . TYR B 1 133 ? 111.808 107.461 121.379 1.00 54.26  ?  133 TYR C CE2   1 
ATOM 3043 C CZ    . TYR B 1 133 ? 112.420 106.319 120.922 1.00 54.26  ?  133 TYR C CZ    1 
ATOM 3044 O OH    . TYR B 1 133 ? 113.671 105.985 121.384 1.00 54.26  ?  133 TYR C OH    1 
ATOM 3045 N N     . SER B 1 134 ? 105.653 108.311 120.840 1.00 51.57  ?  134 SER C N     1 
ATOM 3046 C CA    . SER B 1 134 ? 104.373 108.989 120.664 1.00 51.57  ?  134 SER C CA    1 
ATOM 3047 C C     . SER B 1 134 ? 104.474 110.116 119.641 1.00 51.57  ?  134 SER C C     1 
ATOM 3048 O O     . SER B 1 134 ? 103.816 110.082 118.596 1.00 51.57  ?  134 SER C O     1 
ATOM 3049 C CB    . SER B 1 134 ? 103.880 109.527 122.008 1.00 51.57  ?  134 SER C CB    1 
ATOM 3050 O OG    . SER B 1 134 ? 103.977 108.535 123.014 1.00 51.57  ?  134 SER C OG    1 
ATOM 3051 N N     . CYS B 1 135 ? 105.294 111.123 119.926 1.00 44.55  ?  135 CYS C N     1 
ATOM 3052 C CA    . CYS B 1 135 ? 105.477 112.266 119.040 1.00 44.55  ?  135 CYS C CA    1 
ATOM 3053 C C     . CYS B 1 135 ? 106.671 112.012 118.131 1.00 44.55  ?  135 CYS C C     1 
ATOM 3054 O O     . CYS B 1 135 ? 107.787 111.793 118.613 1.00 44.55  ?  135 CYS C O     1 
ATOM 3055 C CB    . CYS B 1 135 ? 105.675 113.555 119.841 1.00 44.55  ?  135 CYS C CB    1 
ATOM 3056 S SG    . CYS B 1 135 ? 106.421 114.917 118.899 1.00 44.55  ?  135 CYS C SG    1 
ATOM 3057 N N     . VAL B 1 136 ? 106.433 112.036 116.824 1.00 38.51  ?  136 VAL C N     1 
ATOM 3058 C CA    . VAL B 1 136 ? 107.486 111.943 115.820 1.00 38.51  ?  136 VAL C CA    1 
ATOM 3059 C C     . VAL B 1 136 ? 107.409 113.197 114.963 1.00 38.51  ?  136 VAL C C     1 
ATOM 3060 O O     . VAL B 1 136 ? 106.369 113.475 114.354 1.00 38.51  ?  136 VAL C O     1 
ATOM 3061 C CB    . VAL B 1 136 ? 107.353 110.676 114.962 1.00 38.51  ?  136 VAL C CB    1 
ATOM 3062 C CG1   . VAL B 1 136 ? 108.029 110.870 113.615 1.00 38.51  ?  136 VAL C CG1   1 
ATOM 3063 C CG2   . VAL B 1 136 ? 107.945 109.484 115.688 1.00 38.51  ?  136 VAL C CG2   1 
ATOM 3064 N N     . VAL B 1 137 ? 108.500 113.953 114.922 1.00 37.25  ?  137 VAL C N     1 
ATOM 3065 C CA    . VAL B 1 137 ? 108.548 115.234 114.230 1.00 37.25  ?  137 VAL C CA    1 
ATOM 3066 C C     . VAL B 1 137 ? 109.756 115.244 113.307 1.00 37.25  ?  137 VAL C C     1 
ATOM 3067 O O     . VAL B 1 137 ? 110.867 114.912 113.732 1.00 37.25  ?  137 VAL C O     1 
ATOM 3068 C CB    . VAL B 1 137 ? 108.622 116.409 115.223 1.00 37.25  ?  137 VAL C CB    1 
ATOM 3069 C CG1   . VAL B 1 137 ? 109.051 117.676 114.516 1.00 37.25  ?  137 VAL C CG1   1 
ATOM 3070 C CG2   . VAL B 1 137 ? 107.284 116.611 115.894 1.00 37.25  ?  137 VAL C CG2   1 
ATOM 3071 N N     . LYS B 1 138 ? 109.540 115.623 112.050 1.00 33.81  ?  138 LYS C N     1 
ATOM 3072 C CA    . LYS B 1 138 ? 110.623 115.817 111.097 1.00 33.81  ?  138 LYS C CA    1 
ATOM 3073 C C     . LYS B 1 138 ? 110.493 117.202 110.487 1.00 33.81  ?  138 LYS C C     1 
ATOM 3074 O O     . LYS B 1 138 ? 109.391 117.619 110.118 1.00 33.81  ?  138 LYS C O     1 
ATOM 3075 C CB    . LYS B 1 138 ? 110.612 114.742 110.006 1.00 33.81  ?  138 LYS C CB    1 
ATOM 3076 C CG    . LYS B 1 138 ? 109.271 114.539 109.333 1.00 33.81  ?  138 LYS C CG    1 
ATOM 3077 C CD    . LYS B 1 138 ? 109.299 113.337 108.401 1.00 33.81  ?  138 LYS C CD    1 
ATOM 3078 C CE    . LYS B 1 138 ? 110.551 113.325 107.538 1.00 33.81  ?  138 LYS C CE    1 
ATOM 3079 N NZ    . LYS B 1 138 ? 110.625 114.510 106.640 1.00 33.81  1  138 LYS C NZ    1 
ATOM 3080 N N     . MET B 1 139 ? 111.612 117.910 110.385 1.00 29.47  ?  139 MET C N     1 
ATOM 3081 C CA    . MET B 1 139 ? 111.617 119.290 109.923 1.00 29.47  ?  139 MET C CA    1 
ATOM 3082 C C     . MET B 1 139 ? 113.001 119.606 109.379 1.00 29.47  ?  139 MET C C     1 
ATOM 3083 O O     . MET B 1 139 ? 113.956 118.868 109.648 1.00 29.47  ?  139 MET C O     1 
ATOM 3084 C CB    . MET B 1 139 ? 111.245 120.255 111.058 1.00 29.47  ?  139 MET C CB    1 
ATOM 3085 C CG    . MET B 1 139 ? 112.226 120.274 112.206 1.00 29.47  ?  139 MET C CG    1 
ATOM 3086 S SD    . MET B 1 139 ? 111.367 120.299 113.784 1.00 29.47  ?  139 MET C SD    1 
ATOM 3087 C CE    . MET B 1 139 ? 112.747 120.286 114.914 1.00 29.47  ?  139 MET C CE    1 
ATOM 3088 N N     . PRO B 1 140 ? 113.139 120.675 108.594 1.00 36.11  ?  140 PRO C N     1 
ATOM 3089 C CA    . PRO B 1 140 ? 114.464 121.036 108.075 1.00 36.11  ?  140 PRO C CA    1 
ATOM 3090 C C     . PRO B 1 140 ? 115.462 121.264 109.199 1.00 36.11  ?  140 PRO C C     1 
ATOM 3091 O O     . PRO B 1 140 ? 115.140 121.854 110.232 1.00 36.11  ?  140 PRO C O     1 
ATOM 3092 C CB    . PRO B 1 140 ? 114.197 122.323 107.291 1.00 36.11  ?  140 PRO C CB    1 
ATOM 3093 C CG    . PRO B 1 140 ? 112.772 122.232 106.903 1.00 36.11  ?  140 PRO C CG    1 
ATOM 3094 C CD    . PRO B 1 140 ? 112.076 121.513 108.015 1.00 36.11  ?  140 PRO C CD    1 
ATOM 3095 N N     . SER B 1 141 ? 116.689 120.787 108.984 1.00 30.66  ?  141 SER C N     1 
ATOM 3096 C CA    . SER B 1 141 ? 117.711 120.874 110.021 1.00 30.66  ?  141 SER C CA    1 
ATOM 3097 C C     . SER B 1 141 ? 118.082 122.319 110.318 1.00 30.66  ?  141 SER C C     1 
ATOM 3098 O O     . SER B 1 141 ? 118.352 122.671 111.472 1.00 30.66  ?  141 SER C O     1 
ATOM 3099 C CB    . SER B 1 141 ? 118.946 120.081 109.605 1.00 30.66  ?  141 SER C CB    1 
ATOM 3100 O OG    . SER B 1 141 ? 119.338 120.419 108.288 1.00 30.66  ?  141 SER C OG    1 
ATOM 3101 N N     . GLY B 1 142 ? 118.116 123.166 109.289 1.00 35.08  ?  142 GLY C N     1 
ATOM 3102 C CA    . GLY B 1 142 ? 118.481 124.557 109.502 1.00 35.08  ?  142 GLY C CA    1 
ATOM 3103 C C     . GLY B 1 142 ? 117.531 125.274 110.441 1.00 35.08  ?  142 GLY C C     1 
ATOM 3104 O O     . GLY B 1 142 ? 117.961 126.031 111.314 1.00 35.08  ?  142 GLY C O     1 
ATOM 3105 N N     . GLU B 1 143 ? 116.227 125.042 110.277 1.00 36.96  ?  143 GLU C N     1 
ATOM 3106 C CA    . GLU B 1 143 ? 115.249 125.676 111.154 1.00 36.96  ?  143 GLU C CA    1 
ATOM 3107 C C     . GLU B 1 143 ? 115.419 125.220 112.597 1.00 36.96  ?  143 GLU C C     1 
ATOM 3108 O O     . GLU B 1 143 ? 115.348 126.035 113.523 1.00 36.96  ?  143 GLU C O     1 
ATOM 3109 C CB    . GLU B 1 143 ? 113.834 125.382 110.662 1.00 36.96  ?  143 GLU C CB    1 
ATOM 3110 C CG    . GLU B 1 143 ? 113.397 126.246 109.496 1.00 36.96  ?  143 GLU C CG    1 
ATOM 3111 C CD    . GLU B 1 143 ? 111.894 126.248 109.307 1.00 36.96  ?  143 GLU C CD    1 
ATOM 3112 O OE1   . GLU B 1 143 ? 111.189 125.656 110.149 1.00 36.96  ?  143 GLU C OE1   1 
ATOM 3113 O OE2   . GLU B 1 143 ? 111.418 126.843 108.318 1.00 36.96  -1 143 GLU C OE2   1 
ATOM 3114 N N     . PHE B 1 144 ? 115.645 123.922 112.809 1.00 31.93  ?  144 PHE C N     1 
ATOM 3115 C CA    . PHE B 1 144 ? 115.840 123.422 114.166 1.00 31.93  ?  144 PHE C CA    1 
ATOM 3116 C C     . PHE B 1 144 ? 117.099 124.005 114.793 1.00 31.93  ?  144 PHE C C     1 
ATOM 3117 O O     . PHE B 1 144 ? 117.093 124.403 115.966 1.00 31.93  ?  144 PHE C O     1 
ATOM 3118 C CB    . PHE B 1 144 ? 115.904 121.897 114.153 1.00 31.93  ?  144 PHE C CB    1 
ATOM 3119 C CG    . PHE B 1 144 ? 116.161 121.288 115.500 1.00 31.93  ?  144 PHE C CG    1 
ATOM 3120 C CD1   . PHE B 1 144 ? 115.409 121.659 116.598 1.00 31.93  ?  144 PHE C CD1   1 
ATOM 3121 C CD2   . PHE B 1 144 ? 117.153 120.340 115.667 1.00 31.93  ?  144 PHE C CD2   1 
ATOM 3122 C CE1   . PHE B 1 144 ? 115.641 121.096 117.834 1.00 31.93  ?  144 PHE C CE1   1 
ATOM 3123 C CE2   . PHE B 1 144 ? 117.391 119.777 116.902 1.00 31.93  ?  144 PHE C CE2   1 
ATOM 3124 C CZ    . PHE B 1 144 ? 116.634 120.156 117.986 1.00 31.93  ?  144 PHE C CZ    1 
ATOM 3125 N N     . ALA B 1 145 ? 118.190 124.066 114.027 1.00 31.86  ?  145 ALA C N     1 
ATOM 3126 C CA    . ALA B 1 145 ? 119.424 124.637 114.553 1.00 31.86  ?  145 ALA C CA    1 
ATOM 3127 C C     . ALA B 1 145 ? 119.244 126.107 114.899 1.00 31.86  ?  145 ALA C C     1 
ATOM 3128 O O     . ALA B 1 145 ? 119.716 126.571 115.945 1.00 31.86  ?  145 ALA C O     1 
ATOM 3129 C CB    . ALA B 1 145 ? 120.557 124.459 113.546 1.00 31.86  ?  145 ALA C CB    1 
ATOM 3130 N N     . ARG B 1 146 ? 118.558 126.857 114.034 1.00 36.16  ?  146 ARG C N     1 
ATOM 3131 C CA    . ARG B 1 146 ? 118.321 128.269 114.307 1.00 36.16  ?  146 ARG C CA    1 
ATOM 3132 C C     . ARG B 1 146 ? 117.438 128.451 115.533 1.00 36.16  ?  146 ARG C C     1 
ATOM 3133 O O     . ARG B 1 146 ? 117.666 129.359 116.339 1.00 36.16  ?  146 ARG C O     1 
ATOM 3134 C CB    . ARG B 1 146 ? 117.699 128.937 113.083 1.00 36.16  ?  146 ARG C CB    1 
ATOM 3135 C CG    . ARG B 1 146 ? 117.713 130.453 113.128 1.00 36.16  ?  146 ARG C CG    1 
ATOM 3136 C CD    . ARG B 1 146 ? 118.038 131.048 111.759 1.00 36.16  ?  146 ARG C CD    1 
ATOM 3137 N NE    . ARG B 1 146 ? 117.392 130.360 110.644 1.00 36.16  ?  146 ARG C NE    1 
ATOM 3138 C CZ    . ARG B 1 146 ? 116.081 130.262 110.462 1.00 36.16  ?  146 ARG C CZ    1 
ATOM 3139 N NH1   . ARG B 1 146 ? 115.221 130.847 111.279 1.00 36.16  1  146 ARG C NH1   1 
ATOM 3140 N NH2   . ARG B 1 146 ? 115.621 129.572 109.423 1.00 36.16  ?  146 ARG C NH2   1 
ATOM 3141 N N     . ILE B 1 147 ? 116.431 127.592 115.698 1.00 33.42  ?  147 ILE C N     1 
ATOM 3142 C CA    . ILE B 1 147 ? 115.559 127.678 116.866 1.00 33.42  ?  147 ILE C CA    1 
ATOM 3143 C C     . ILE B 1 147 ? 116.354 127.436 118.141 1.00 33.42  ?  147 ILE C C     1 
ATOM 3144 O O     . ILE B 1 147 ? 116.225 128.175 119.126 1.00 33.42  ?  147 ILE C O     1 
ATOM 3145 C CB    . ILE B 1 147 ? 114.391 126.686 116.736 1.00 33.42  ?  147 ILE C CB    1 
ATOM 3146 C CG1   . ILE B 1 147 ? 113.305 127.260 115.829 1.00 33.42  ?  147 ILE C CG1   1 
ATOM 3147 C CG2   . ILE B 1 147 ? 113.820 126.350 118.098 1.00 33.42  ?  147 ILE C CG2   1 
ATOM 3148 C CD1   . ILE B 1 147 ? 112.245 126.258 115.451 1.00 33.42  ?  147 ILE C CD1   1 
ATOM 3149 N N     . CYS B 1 148 ? 117.189 126.395 118.144 1.00 31.66  ?  148 CYS C N     1 
ATOM 3150 C CA    . CYS B 1 148 ? 117.988 126.106 119.332 1.00 31.66  ?  148 CYS C CA    1 
ATOM 3151 C C     . CYS B 1 148 ? 118.959 127.240 119.636 1.00 31.66  ?  148 CYS C C     1 
ATOM 3152 O O     . CYS B 1 148 ? 119.110 127.644 120.796 1.00 31.66  ?  148 CYS C O     1 
ATOM 3153 C CB    . CYS B 1 148 ? 118.739 124.790 119.157 1.00 31.66  ?  148 CYS C CB    1 
ATOM 3154 S SG    . CYS B 1 148 ? 117.714 123.330 119.390 1.00 31.66  ?  148 CYS C SG    1 
ATOM 3155 N N     . ARG B 1 149 ? 119.618 127.775 118.606 1.00 36.16  ?  149 ARG C N     1 
ATOM 3156 C CA    . ARG B 1 149 ? 120.563 128.864 118.831 1.00 36.16  ?  149 ARG C CA    1 
ATOM 3157 C C     . ARG B 1 149 ? 119.857 130.108 119.353 1.00 36.16  ?  149 ARG C C     1 
ATOM 3158 O O     . ARG B 1 149 ? 120.384 130.809 120.224 1.00 36.16  ?  149 ARG C O     1 
ATOM 3159 C CB    . ARG B 1 149 ? 121.321 129.176 117.543 1.00 36.16  ?  149 ARG C CB    1 
ATOM 3160 C CG    . ARG B 1 149 ? 122.609 129.947 117.761 1.00 36.16  ?  149 ARG C CG    1 
ATOM 3161 C CD    . ARG B 1 149 ? 123.065 130.619 116.479 1.00 36.16  ?  149 ARG C CD    1 
ATOM 3162 N NE    . ARG B 1 149 ? 122.134 131.657 116.055 1.00 36.16  ?  149 ARG C NE    1 
ATOM 3163 C CZ    . ARG B 1 149 ? 122.041 132.118 114.816 1.00 36.16  ?  149 ARG C CZ    1 
ATOM 3164 N NH1   . ARG B 1 149 ? 122.811 131.654 113.846 1.00 36.16  1  149 ARG C NH1   1 
ATOM 3165 N NH2   . ARG B 1 149 ? 121.152 133.069 114.542 1.00 36.16  ?  149 ARG C NH2   1 
ATOM 3166 N N     . ASP B 1 150 ? 118.666 130.404 118.828 1.00 36.94  ?  150 ASP C N     1 
ATOM 3167 C CA    . ASP B 1 150 ? 117.911 131.555 119.310 1.00 36.94  ?  150 ASP C CA    1 
ATOM 3168 C C     . ASP B 1 150 ? 117.487 131.372 120.759 1.00 36.94  ?  150 ASP C C     1 
ATOM 3169 O O     . ASP B 1 150 ? 117.608 132.298 121.568 1.00 36.94  ?  150 ASP C O     1 
ATOM 3170 C CB    . ASP B 1 150 ? 116.687 131.785 118.426 1.00 36.94  ?  150 ASP C CB    1 
ATOM 3171 C CG    . ASP B 1 150 ? 117.045 132.367 117.078 1.00 36.94  ?  150 ASP C CG    1 
ATOM 3172 O OD1   . ASP B 1 150 ? 118.213 132.768 116.894 1.00 36.94  ?  150 ASP C OD1   1 
ATOM 3173 O OD2   . ASP B 1 150 ? 116.158 132.422 116.201 1.00 36.94  -1 150 ASP C OD2   1 
ATOM 3174 N N     . LEU B 1 151 ? 116.990 130.185 121.109 1.00 30.79  ?  151 LEU C N     1 
ATOM 3175 C CA    . LEU B 1 151 ? 116.518 129.963 122.469 1.00 30.79  ?  151 LEU C CA    1 
ATOM 3176 C C     . LEU B 1 151 ? 117.656 129.845 123.470 1.00 30.79  ?  151 LEU C C     1 
ATOM 3177 O O     . LEU B 1 151 ? 117.420 130.000 124.672 1.00 30.79  ?  151 LEU C O     1 
ATOM 3178 C CB    . LEU B 1 151 ? 115.643 128.713 122.529 1.00 30.79  ?  151 LEU C CB    1 
ATOM 3179 C CG    . LEU B 1 151 ? 114.229 128.873 121.980 1.00 30.79  ?  151 LEU C CG    1 
ATOM 3180 C CD1   . LEU B 1 151 ? 113.356 127.714 122.417 1.00 30.79  ?  151 LEU C CD1   1 
ATOM 3181 C CD2   . LEU B 1 151 ? 113.639 130.190 122.436 1.00 30.79  ?  151 LEU C CD2   1 
ATOM 3182 N N     . SER B 1 152 ? 118.878 129.567 123.011 1.00 35.41  ?  152 SER C N     1 
ATOM 3183 C CA    . SER B 1 152 ? 119.997 129.481 123.944 1.00 35.41  ?  152 SER C CA    1 
ATOM 3184 C C     . SER B 1 152 ? 120.256 130.807 124.646 1.00 35.41  ?  152 SER C C     1 
ATOM 3185 O O     . SER B 1 152 ? 120.668 130.820 125.810 1.00 35.41  ?  152 SER C O     1 
ATOM 3186 C CB    . SER B 1 152 ? 121.257 129.017 123.216 1.00 35.41  ?  152 SER C CB    1 
ATOM 3187 O OG    . SER B 1 152 ? 121.281 127.606 123.097 1.00 35.41  ?  152 SER C OG    1 
ATOM 3188 N N     . HIS B 1 153 ? 120.027 131.929 123.960 1.00 37.14  ?  153 HIS C N     1 
ATOM 3189 C CA    . HIS B 1 153 ? 120.286 133.231 124.567 1.00 37.14  ?  153 HIS C CA    1 
ATOM 3190 C C     . HIS B 1 153 ? 119.337 133.509 125.727 1.00 37.14  ?  153 HIS C C     1 
ATOM 3191 O O     . HIS B 1 153 ? 119.747 134.071 126.748 1.00 37.14  ?  153 HIS C O     1 
ATOM 3192 C CB    . HIS B 1 153 ? 120.173 134.335 123.518 1.00 37.14  ?  153 HIS C CB    1 
ATOM 3193 C CG    . HIS B 1 153 ? 120.993 134.092 122.291 1.00 37.14  ?  153 HIS C CG    1 
ATOM 3194 N ND1   . HIS B 1 153 ? 122.369 134.164 122.289 1.00 37.14  ?  153 HIS C ND1   1 
ATOM 3195 C CD2   . HIS B 1 153 ? 120.631 133.783 121.024 1.00 37.14  ?  153 HIS C CD2   1 
ATOM 3196 C CE1   . HIS B 1 153 ? 122.820 133.906 121.074 1.00 37.14  ?  153 HIS C CE1   1 
ATOM 3197 N NE2   . HIS B 1 153 ? 121.785 133.671 120.288 1.00 37.14  ?  153 HIS C NE2   1 
ATOM 3198 N N     . ILE B 1 154 ? 118.068 133.127 125.588 1.00 34.91  ?  154 ILE C N     1 
ATOM 3199 C CA    . ILE B 1 154 ? 117.061 133.508 126.575 1.00 34.91  ?  154 ILE C CA    1 
ATOM 3200 C C     . ILE B 1 154 ? 117.271 132.747 127.878 1.00 34.91  ?  154 ILE C C     1 
ATOM 3201 O O     . ILE B 1 154 ? 117.534 133.342 128.929 1.00 34.91  ?  154 ILE C O     1 
ATOM 3202 C CB    . ILE B 1 154 ? 115.646 133.279 126.017 1.00 34.91  ?  154 ILE C CB    1 
ATOM 3203 C CG1   . ILE B 1 154 ? 115.405 134.175 124.805 1.00 34.91  ?  154 ILE C CG1   1 
ATOM 3204 C CG2   . ILE B 1 154 ? 114.607 133.548 127.085 1.00 34.91  ?  154 ILE C CG2   1 
ATOM 3205 C CD1   . ILE B 1 154 ? 115.684 135.631 125.070 1.00 34.91  ?  154 ILE C CD1   1 
ATOM 3206 N N     . GLY B 1 155 ? 117.161 131.424 127.830 1.00 35.63  ?  155 GLY C N     1 
ATOM 3207 C CA    . GLY B 1 155 ? 117.246 130.599 129.012 1.00 35.63  ?  155 GLY C CA    1 
ATOM 3208 C C     . GLY B 1 155 ? 118.191 129.431 128.808 1.00 35.63  ?  155 GLY C C     1 
ATOM 3209 O O     . GLY B 1 155 ? 119.153 129.501 128.043 1.00 35.63  ?  155 GLY C O     1 
ATOM 3210 N N     . ASP B 1 156 ? 117.900 128.344 129.520 1.00 35.08  ?  156 ASP C N     1 
ATOM 3211 C CA    . ASP B 1 156 ? 118.697 127.128 129.433 1.00 35.08  ?  156 ASP C CA    1 
ATOM 3212 C C     . ASP B 1 156 ? 117.878 125.858 129.268 1.00 35.08  ?  156 ASP C C     1 
ATOM 3213 O O     . ASP B 1 156 ? 118.426 124.857 128.794 1.00 35.08  ?  156 ASP C O     1 
ATOM 3214 C CB    . ASP B 1 156 ? 119.588 126.982 130.674 1.00 35.08  ?  156 ASP C CB    1 
ATOM 3215 C CG    . ASP B 1 156 ? 120.643 125.911 130.509 1.00 35.08  ?  156 ASP C CG    1 
ATOM 3216 O OD1   . ASP B 1 156 ? 121.740 126.228 130.003 1.00 35.08  ?  156 ASP C OD1   1 
ATOM 3217 O OD2   . ASP B 1 156 ? 120.375 124.750 130.882 1.00 35.08  -1 156 ASP C OD2   1 
ATOM 3218 N N     . ALA B 1 157 ? 116.601 125.857 129.633 1.00 31.03  ?  157 ALA C N     1 
ATOM 3219 C CA    . ALA B 1 157 ? 115.739 124.696 129.477 1.00 31.03  ?  157 ALA C CA    1 
ATOM 3220 C C     . ALA B 1 157 ? 114.633 125.009 128.481 1.00 31.03  ?  157 ALA C C     1 
ATOM 3221 O O     . ALA B 1 157 ? 114.008 126.071 128.546 1.00 31.03  ?  157 ALA C O     1 
ATOM 3222 C CB    . ALA B 1 157 ? 115.133 124.277 130.817 1.00 31.03  ?  157 ALA C CB    1 
ATOM 3223 N N     . VAL B 1 158 ? 114.393 124.080 127.561 1.00 31.78  ?  158 VAL C N     1 
ATOM 3224 C CA    . VAL B 1 158 ? 113.386 124.235 126.519 1.00 31.78  ?  158 VAL C CA    1 
ATOM 3225 C C     . VAL B 1 158 ? 112.242 123.277 126.811 1.00 31.78  ?  158 VAL C C     1 
ATOM 3226 O O     . VAL B 1 158 ? 112.468 122.095 127.095 1.00 31.78  ?  158 VAL C O     1 
ATOM 3227 C CB    . VAL B 1 158 ? 113.979 123.994 125.120 1.00 31.78  ?  158 VAL C CB    1 
ATOM 3228 C CG1   . VAL B 1 158 ? 114.706 122.666 125.065 1.00 31.78  ?  158 VAL C CG1   1 
ATOM 3229 C CG2   . VAL B 1 158 ? 112.889 124.038 124.072 1.00 31.78  ?  158 VAL C CG2   1 
ATOM 3230 N N     . VAL B 1 159 ? 111.018 123.789 126.766 1.00 35.63  ?  159 VAL C N     1 
ATOM 3231 C CA    . VAL B 1 159 ? 109.824 122.997 127.047 1.00 35.63  ?  159 VAL C CA    1 
ATOM 3232 C C     . VAL B 1 159 ? 109.151 122.742 125.704 1.00 35.63  ?  159 VAL C C     1 
ATOM 3233 O O     . VAL B 1 159 ? 108.352 123.544 125.220 1.00 35.63  ?  159 VAL C O     1 
ATOM 3234 C CB    . VAL B 1 159 ? 108.895 123.697 128.035 1.00 35.63  ?  159 VAL C CB    1 
ATOM 3235 C CG1   . VAL B 1 159 ? 107.718 122.804 128.373 1.00 35.63  ?  159 VAL C CG1   1 
ATOM 3236 C CG2   . VAL B 1 159 ? 109.654 124.080 129.292 1.00 35.63  ?  159 VAL C CG2   1 
ATOM 3237 N N     . ILE B 1 160 ? 109.468 121.605 125.097 1.00 54.26  ?  160 ILE C N     1 
ATOM 3238 C CA    . ILE B 1 160 ? 108.908 121.253 123.797 1.00 54.26  ?  160 ILE C CA    1 
ATOM 3239 C C     . ILE B 1 160 ? 107.479 120.771 123.995 1.00 54.26  ?  160 ILE C C     1 
ATOM 3240 O O     . ILE B 1 160 ? 107.228 119.838 124.764 1.00 54.26  ?  160 ILE C O     1 
ATOM 3241 C CB    . ILE B 1 160 ? 109.759 120.184 123.101 1.00 54.26  ?  160 ILE C CB    1 
ATOM 3242 C CG1   . ILE B 1 160 ? 111.182 120.697 122.890 1.00 54.26  ?  160 ILE C CG1   1 
ATOM 3243 C CG2   . ILE B 1 160 ? 109.130 119.787 121.781 1.00 54.26  ?  160 ILE C CG2   1 
ATOM 3244 C CD1   . ILE B 1 160 ? 112.074 119.729 122.158 1.00 54.26  ?  160 ILE C CD1   1 
ATOM 3245 N N     . SER B 1 161 ? 106.541 121.404 123.303 1.00 47.07  ?  161 SER C N     1 
ATOM 3246 C CA    . SER B 1 161 ? 105.130 121.033 123.354 1.00 47.07  ?  161 SER C CA    1 
ATOM 3247 C C     . SER B 1 161 ? 104.743 120.535 121.967 1.00 47.07  ?  161 SER C C     1 
ATOM 3248 O O     . SER B 1 161 ? 104.391 121.327 121.090 1.00 47.07  ?  161 SER C O     1 
ATOM 3249 C CB    . SER B 1 161 ? 104.267 122.212 123.787 1.00 47.07  ?  161 SER C CB    1 
ATOM 3250 O OG    . SER B 1 161 ? 104.650 122.684 125.067 1.00 47.07  ?  161 SER C OG    1 
ATOM 3251 N N     . CYS B 1 162 ? 104.800 119.220 121.776 1.00 53.11  ?  162 CYS C N     1 
ATOM 3252 C CA    . CYS B 1 162 ? 104.544 118.634 120.468 1.00 53.11  ?  162 CYS C CA    1 
ATOM 3253 C C     . CYS B 1 162 ? 103.052 118.677 120.160 1.00 53.11  ?  162 CYS C C     1 
ATOM 3254 O O     . CYS B 1 162 ? 102.400 117.634 120.066 1.00 53.11  ?  162 CYS C O     1 
ATOM 3255 C CB    . CYS B 1 162 ? 105.082 117.198 120.422 1.00 53.11  ?  162 CYS C CB    1 
ATOM 3256 S SG    . CYS B 1 162 ? 105.030 116.397 118.808 1.00 53.11  ?  162 CYS C SG    1 
ATOM 3257 N N     . ALA B 1 163 ? 102.504 119.878 120.001 1.00 60.38  ?  163 ALA C N     1 
ATOM 3258 C CA    . ALA B 1 163 ? 101.084 120.051 119.739 1.00 60.38  ?  163 ALA C CA    1 
ATOM 3259 C C     . ALA B 1 163 ? 100.775 119.779 118.272 1.00 60.38  ?  163 ALA C C     1 
ATOM 3260 O O     . ALA B 1 163 ? 101.582 120.067 117.384 1.00 60.38  ?  163 ALA C O     1 
ATOM 3261 C CB    . ALA B 1 163 ? 100.630 121.462 120.114 1.00 60.38  ?  163 ALA C CB    1 
ATOM 3262 N N     . LYS B 1 164 ? 99.586  119.222 118.025 1.00 73.69  ?  164 LYS C N     1 
ATOM 3263 C CA    . LYS B 1 164 ? 99.214  118.821 116.672 1.00 73.69  ?  164 LYS C CA    1 
ATOM 3264 C C     . LYS B 1 164 ? 98.996  120.007 115.743 1.00 73.69  ?  164 LYS C C     1 
ATOM 3265 O O     . LYS B 1 164 ? 99.017  119.830 114.520 1.00 73.69  ?  164 LYS C O     1 
ATOM 3266 C CB    . LYS B 1 164 ? 97.957  117.951 116.705 1.00 73.69  ?  164 LYS C CB    1 
ATOM 3267 C CG    . LYS B 1 164 ? 97.991  116.787 115.727 1.00 73.69  ?  164 LYS C CG    1 
ATOM 3268 C CD    . LYS B 1 164 ? 96.843  115.822 115.969 1.00 73.69  ?  164 LYS C CD    1 
ATOM 3269 C CE    . LYS B 1 164 ? 96.864  114.679 114.967 1.00 73.69  ?  164 LYS C CE    1 
ATOM 3270 N NZ    . LYS B 1 164 ? 95.774  113.697 115.219 1.00 73.69  1  164 LYS C NZ    1 
ATOM 3271 N N     . ASP B 1 165 ? 98.783  121.205 116.285 1.00 66.48  ?  165 ASP C N     1 
ATOM 3272 C CA    . ASP B 1 165 ? 98.640  122.393 115.453 1.00 66.48  ?  165 ASP C CA    1 
ATOM 3273 C C     . ASP B 1 165 ? 99.981  122.980 115.034 1.00 66.48  ?  165 ASP C C     1 
ATOM 3274 O O     . ASP B 1 165 ? 100.007 123.930 114.244 1.00 66.48  ?  165 ASP C O     1 
ATOM 3275 C CB    . ASP B 1 165 ? 97.819  123.452 116.193 1.00 66.48  ?  165 ASP C CB    1 
ATOM 3276 C CG    . ASP B 1 165 ? 97.272  124.515 115.265 1.00 66.48  ?  165 ASP C CG    1 
ATOM 3277 O OD1   . ASP B 1 165 ? 97.141  124.237 114.054 1.00 66.48  ?  165 ASP C OD1   1 
ATOM 3278 O OD2   . ASP B 1 165 ? 96.973  125.629 115.745 1.00 66.48  -1 165 ASP C OD2   1 
ATOM 3279 N N     . GLY B 1 166 ? 101.086 122.435 115.534 1.00 52.27  ?  166 GLY C N     1 
ATOM 3280 C CA    . GLY B 1 166 ? 102.406 122.950 115.234 1.00 52.27  ?  166 GLY C CA    1 
ATOM 3281 C C     . GLY B 1 166 ? 103.316 122.868 116.440 1.00 52.27  ?  166 GLY C C     1 
ATOM 3282 O O     . GLY B 1 166 ? 102.915 123.238 117.547 1.00 52.27  ?  166 GLY C O     1 
ATOM 3283 N N     . VAL B 1 167 ? 104.540 122.373 116.244 1.00 42.34  ?  167 VAL C N     1 
ATOM 3284 C CA    . VAL B 1 167 ? 105.470 122.240 117.356 1.00 42.34  ?  167 VAL C CA    1 
ATOM 3285 C C     . VAL B 1 167 ? 105.754 123.611 117.947 1.00 42.34  ?  167 VAL C C     1 
ATOM 3286 O O     . VAL B 1 167 ? 105.968 124.592 117.224 1.00 42.34  ?  167 VAL C O     1 
ATOM 3287 C CB    . VAL B 1 167 ? 106.759 121.541 116.894 1.00 42.34  ?  167 VAL C CB    1 
ATOM 3288 C CG1   . VAL B 1 167 ? 107.344 122.244 115.684 1.00 42.34  ?  167 VAL C CG1   1 
ATOM 3289 C CG2   . VAL B 1 167 ? 107.770 121.484 118.024 1.00 42.34  ?  167 VAL C CG2   1 
ATOM 3290 N N     . LYS B 1 168 ? 105.735 123.692 119.275 1.00 42.14  ?  168 LYS C N     1 
ATOM 3291 C CA    . LYS B 1 168 ? 105.857 124.961 119.985 1.00 42.14  ?  168 LYS C CA    1 
ATOM 3292 C C     . LYS B 1 168 ? 106.927 124.832 121.057 1.00 42.14  ?  168 LYS C C     1 
ATOM 3293 O O     . LYS B 1 168 ? 106.704 124.188 122.087 1.00 42.14  ?  168 LYS C O     1 
ATOM 3294 C CB    . LYS B 1 168 ? 104.519 125.369 120.599 1.00 42.14  ?  168 LYS C CB    1 
ATOM 3295 C CG    . LYS B 1 168 ? 104.602 126.538 121.557 1.00 42.14  ?  168 LYS C CG    1 
ATOM 3296 C CD    . LYS B 1 168 ? 103.226 126.916 122.069 1.00 42.14  ?  168 LYS C CD    1 
ATOM 3297 C CE    . LYS B 1 168 ? 103.316 127.671 123.381 1.00 42.14  ?  168 LYS C CE    1 
ATOM 3298 N NZ    . LYS B 1 168 ? 101.967 128.012 123.910 1.00 42.14  1  168 LYS C NZ    1 
ATOM 3299 N N     . PHE B 1 169 ? 108.082 125.441 120.819 1.00 54.26  ?  169 PHE C N     1 
ATOM 3300 C CA    . PHE B 1 169 ? 109.147 125.487 121.807 1.00 54.26  ?  169 PHE C CA    1 
ATOM 3301 C C     . PHE B 1 169 ? 108.886 126.625 122.783 1.00 54.26  ?  169 PHE C C     1 
ATOM 3302 O O     . PHE B 1 169 ? 108.112 127.541 122.499 1.00 54.26  ?  169 PHE C O     1 
ATOM 3303 C CB    . PHE B 1 169 ? 110.510 125.672 121.137 1.00 54.26  ?  169 PHE C CB    1 
ATOM 3304 C CG    . PHE B 1 169 ? 110.843 124.612 120.122 1.00 54.26  ?  169 PHE C CG    1 
ATOM 3305 C CD1   . PHE B 1 169 ? 110.239 124.604 118.876 1.00 54.26  ?  169 PHE C CD1   1 
ATOM 3306 C CD2   . PHE B 1 169 ? 111.769 123.628 120.411 1.00 54.26  ?  169 PHE C CD2   1 
ATOM 3307 C CE1   . PHE B 1 169 ? 110.548 123.635 117.946 1.00 54.26  ?  169 PHE C CE1   1 
ATOM 3308 C CE2   . PHE B 1 169 ? 112.080 122.656 119.483 1.00 54.26  ?  169 PHE C CE2   1 
ATOM 3309 C CZ    . PHE B 1 169 ? 111.468 122.660 118.250 1.00 54.26  ?  169 PHE C CZ    1 
ATOM 3310 N N     . SER B 1 170 ? 109.529 126.555 123.946 1.00 35.15  ?  170 SER C N     1 
ATOM 3311 C CA    . SER B 1 170 ? 109.366 127.584 124.967 1.00 35.15  ?  170 SER C CA    1 
ATOM 3312 C C     . SER B 1 170 ? 110.547 127.538 125.921 1.00 35.15  ?  170 SER C C     1 
ATOM 3313 O O     . SER B 1 170 ? 110.929 126.460 126.384 1.00 35.15  ?  170 SER C O     1 
ATOM 3314 C CB    . SER B 1 170 ? 108.060 127.400 125.748 1.00 35.15  ?  170 SER C CB    1 
ATOM 3315 O OG    . SER B 1 170 ? 106.945 127.284 124.883 1.00 35.15  ?  170 SER C OG    1 
ATOM 3316 N N     . ALA B 1 171 ? 111.116 128.704 126.213 1.00 28.37  ?  171 ALA C N     1 
ATOM 3317 C CA    . ALA B 1 171 ? 112.193 128.821 127.182 1.00 28.37  ?  171 ALA C CA    1 
ATOM 3318 C C     . ALA B 1 171 ? 111.965 130.066 128.020 1.00 28.37  ?  171 ALA C C     1 
ATOM 3319 O O     . ALA B 1 171 ? 111.589 131.115 127.491 1.00 28.37  ?  171 ALA C O     1 
ATOM 3320 C CB    . ALA B 1 171 ? 113.563 128.890 126.500 1.00 28.37  ?  171 ALA C CB    1 
ATOM 3321 N N     . SER B 1 172 ? 112.193 129.949 129.324 1.00 37.02  ?  172 SER C N     1 
ATOM 3322 C CA    . SER B 1 172 ? 111.988 131.052 130.251 1.00 37.02  ?  172 SER C CA    1 
ATOM 3323 C C     . SER B 1 172 ? 113.269 131.301 131.029 1.00 37.02  ?  172 SER C C     1 
ATOM 3324 O O     . SER B 1 172 ? 113.868 130.362 131.562 1.00 37.02  ?  172 SER C O     1 
ATOM 3325 C CB    . SER B 1 172 ? 110.832 130.762 131.213 1.00 37.02  ?  172 SER C CB    1 
ATOM 3326 O OG    . SER B 1 172 ? 110.741 131.763 132.210 1.00 37.02  ?  172 SER C OG    1 
ATOM 3327 N N     . GLY B 1 173 ? 113.683 132.562 131.093 1.00 42.81  ?  173 GLY C N     1 
ATOM 3328 C CA    . GLY B 1 173 ? 114.881 132.930 131.817 1.00 42.81  ?  173 GLY C CA    1 
ATOM 3329 C C     . GLY B 1 173 ? 114.733 134.243 132.555 1.00 42.81  ?  173 GLY C C     1 
ATOM 3330 O O     . GLY B 1 173 ? 113.640 134.813 132.608 1.00 42.81  ?  173 GLY C O     1 
ATOM 3331 N N     . GLU B 1 174 ? 115.831 134.733 133.132 1.00 51.66  ?  174 GLU C N     1 
ATOM 3332 C CA    . GLU B 1 174 ? 115.796 135.999 133.856 1.00 51.66  ?  174 GLU C CA    1 
ATOM 3333 C C     . GLU B 1 174 ? 115.542 137.188 132.939 1.00 51.66  ?  174 GLU C C     1 
ATOM 3334 O O     . GLU B 1 174 ? 115.091 138.234 133.415 1.00 51.66  ?  174 GLU C O     1 
ATOM 3335 C CB    . GLU B 1 174 ? 117.104 136.201 134.624 1.00 51.66  ?  174 GLU C CB    1 
ATOM 3336 C CG    . GLU B 1 174 ? 118.264 136.704 133.778 1.00 51.66  ?  174 GLU C CG    1 
ATOM 3337 C CD    . GLU B 1 174 ? 118.648 135.740 132.672 1.00 51.66  ?  174 GLU C CD    1 
ATOM 3338 O OE1   . GLU B 1 174 ? 118.449 134.519 132.847 1.00 51.66  ?  174 GLU C OE1   1 
ATOM 3339 O OE2   . GLU B 1 174 ? 119.149 136.201 131.626 1.00 51.66  -1 174 GLU C OE2   1 
ATOM 3340 N N     . LEU B 1 175 ? 115.821 137.055 131.642 1.00 48.03  ?  175 LEU C N     1 
ATOM 3341 C CA    . LEU B 1 175 ? 115.568 138.130 130.692 1.00 48.03  ?  175 LEU C CA    1 
ATOM 3342 C C     . LEU B 1 175 ? 114.138 138.134 130.172 1.00 48.03  ?  175 LEU C C     1 
ATOM 3343 O O     . LEU B 1 175 ? 113.778 139.033 129.406 1.00 48.03  ?  175 LEU C O     1 
ATOM 3344 C CB    . LEU B 1 175 ? 116.535 138.027 129.512 1.00 48.03  ?  175 LEU C CB    1 
ATOM 3345 C CG    . LEU B 1 175 ? 117.955 138.547 129.738 1.00 48.03  ?  175 LEU C CG    1 
ATOM 3346 C CD1   . LEU B 1 175 ? 118.625 138.855 128.410 1.00 48.03  ?  175 LEU C CD1   1 
ATOM 3347 C CD2   . LEU B 1 175 ? 117.947 139.772 130.637 1.00 48.03  ?  175 LEU C CD2   1 
ATOM 3348 N N     . GLY B 1 176 ? 113.325 137.158 130.563 1.00 39.82  ?  176 GLY C N     1 
ATOM 3349 C CA    . GLY B 1 176 ? 111.971 136.998 130.091 1.00 39.82  ?  176 GLY C CA    1 
ATOM 3350 C C     . GLY B 1 176 ? 111.774 135.597 129.568 1.00 39.82  ?  176 GLY C C     1 
ATOM 3351 O O     . GLY B 1 176 ? 112.586 134.700 129.817 1.00 39.82  ?  176 GLY C O     1 
ATOM 3352 N N     . ASN B 1 177 ? 110.684 135.400 128.834 1.00 30.39  ?  177 ASN C N     1 
ATOM 3353 C CA    . ASN B 1 177 ? 110.392 134.116 128.219 1.00 30.39  ?  177 ASN C CA    1 
ATOM 3354 C C     . ASN B 1 177 ? 109.988 134.330 126.771 1.00 30.39  ?  177 ASN C C     1 
ATOM 3355 O O     . ASN B 1 177 ? 109.349 135.331 126.437 1.00 30.39  ?  177 ASN C O     1 
ATOM 3356 C CB    . ASN B 1 177 ? 109.284 133.373 128.969 1.00 30.39  ?  177 ASN C CB    1 
ATOM 3357 C CG    . ASN B 1 177 ? 108.184 134.293 129.443 1.00 30.39  ?  177 ASN C CG    1 
ATOM 3358 O OD1   . ASN B 1 177 ? 107.937 135.342 128.851 1.00 30.39  ?  177 ASN C OD1   1 
ATOM 3359 N ND2   . ASN B 1 177 ? 107.511 133.904 130.519 1.00 30.39  ?  177 ASN C ND2   1 
ATOM 3360 N N     . GLY B 1 178 ? 110.366 133.387 125.915 1.00 25.99  ?  178 GLY C N     1 
ATOM 3361 C CA    . GLY B 1 178 ? 110.020 133.466 124.512 1.00 25.99  ?  178 GLY C CA    1 
ATOM 3362 C C     . GLY B 1 178 ? 109.660 132.120 123.927 1.00 25.99  ?  178 GLY C C     1 
ATOM 3363 O O     . GLY B 1 178 ? 110.428 131.163 124.048 1.00 25.99  ?  178 GLY C O     1 
ATOM 3364 N N     . ASN B 1 179 ? 108.500 132.029 123.289 1.00 30.22  ?  179 ASN C N     1 
ATOM 3365 C CA    . ASN B 1 179 ? 108.027 130.782 122.711 1.00 30.22  ?  179 ASN C CA    1 
ATOM 3366 C C     . ASN B 1 179 ? 107.948 130.897 121.195 1.00 30.22  ?  179 ASN C C     1 
ATOM 3367 O O     . ASN B 1 179 ? 107.401 131.865 120.661 1.00 30.22  ?  179 ASN C O     1 
ATOM 3368 C CB    . ASN B 1 179 ? 106.663 130.395 123.283 1.00 30.22  ?  179 ASN C CB    1 
ATOM 3369 C CG    . ASN B 1 179 ? 105.674 131.532 123.242 1.00 30.22  ?  179 ASN C CG    1 
ATOM 3370 O OD1   . ASN B 1 179 ? 106.032 132.669 122.941 1.00 30.22  ?  179 ASN C OD1   1 
ATOM 3371 N ND2   . ASN B 1 179 ? 104.417 131.234 123.546 1.00 30.22  ?  179 ASN C ND2   1 
ATOM 3372 N N     . ILE B 1 180 ? 108.492 129.894 120.512 1.00 20.76  ?  180 ILE C N     1 
ATOM 3373 C CA    . ILE B 1 180 ? 108.552 129.846 119.057 1.00 20.76  ?  180 ILE C CA    1 
ATOM 3374 C C     . ILE B 1 180 ? 107.709 128.672 118.589 1.00 20.76  ?  180 ILE C C     1 
ATOM 3375 O O     . ILE B 1 180 ? 107.827 127.566 119.129 1.00 20.76  ?  180 ILE C O     1 
ATOM 3376 C CB    . ILE B 1 180 ? 109.999 129.702 118.557 1.00 20.76  ?  180 ILE C CB    1 
ATOM 3377 C CG1   . ILE B 1 180 ? 110.884 130.788 119.162 1.00 20.76  ?  180 ILE C CG1   1 
ATOM 3378 C CG2   . ILE B 1 180 ? 110.045 129.746 117.045 1.00 20.76  ?  180 ILE C CG2   1 
ATOM 3379 C CD1   . ILE B 1 180 ? 112.356 130.529 118.987 1.00 20.76  ?  180 ILE C CD1   1 
ATOM 3380 N N     . LYS B 1 181 ? 106.865 128.905 117.591 1.00 34.43  ?  181 LYS C N     1 
ATOM 3381 C CA    . LYS B 1 181 ? 106.007 127.862 117.057 1.00 34.43  ?  181 LYS C CA    1 
ATOM 3382 C C     . LYS B 1 181 ? 106.120 127.821 115.541 1.00 34.43  ?  181 LYS C C     1 
ATOM 3383 O O     . LYS B 1 181 ? 106.318 128.847 114.888 1.00 34.43  ?  181 LYS C O     1 
ATOM 3384 C CB    . LYS B 1 181 ? 104.545 128.070 117.463 1.00 34.43  ?  181 LYS C CB    1 
ATOM 3385 C CG    . LYS B 1 181 ? 103.916 129.331 116.907 1.00 34.43  ?  181 LYS C CG    1 
ATOM 3386 C CD    . LYS B 1 181 ? 102.564 129.595 117.543 1.00 34.43  ?  181 LYS C CD    1 
ATOM 3387 C CE    . LYS B 1 181 ? 101.659 128.380 117.439 1.00 34.43  ?  181 LYS C CE    1 
ATOM 3388 N NZ    . LYS B 1 181 ? 101.540 127.898 116.037 1.00 34.43  1  181 LYS C NZ    1 
ATOM 3389 N N     . LEU B 1 182 ? 105.999 126.620 114.992 1.00 34.76  ?  182 LEU C N     1 
ATOM 3390 C CA    . LEU B 1 182 ? 106.002 126.390 113.556 1.00 34.76  ?  182 LEU C CA    1 
ATOM 3391 C C     . LEU B 1 182 ? 104.628 125.892 113.125 1.00 34.76  ?  182 LEU C C     1 
ATOM 3392 O O     . LEU B 1 182 ? 103.718 125.728 113.939 1.00 34.76  ?  182 LEU C O     1 
ATOM 3393 C CB    . LEU B 1 182 ? 107.094 125.392 113.161 1.00 34.76  ?  182 LEU C CB    1 
ATOM 3394 C CG    . LEU B 1 182 ? 108.455 125.555 113.835 1.00 34.76  ?  182 LEU C CG    1 
ATOM 3395 C CD1   . LEU B 1 182 ? 109.430 124.523 113.305 1.00 34.76  ?  182 LEU C CD1   1 
ATOM 3396 C CD2   . LEU B 1 182 ? 108.993 126.953 113.618 1.00 34.76  ?  182 LEU C CD2   1 
ATOM 3397 N N     . SER B 1 183 ? 104.481 125.650 111.827 1.00 46.73  ?  183 SER C N     1 
ATOM 3398 C CA    . SER B 1 183 ? 103.227 125.179 111.264 1.00 46.73  ?  183 SER C CA    1 
ATOM 3399 C C     . SER B 1 183 ? 103.493 124.038 110.295 1.00 46.73  ?  183 SER C C     1 
ATOM 3400 O O     . SER B 1 183 ? 104.543 123.982 109.650 1.00 46.73  ?  183 SER C O     1 
ATOM 3401 C CB    . SER B 1 183 ? 102.480 126.308 110.549 1.00 46.73  ?  183 SER C CB    1 
ATOM 3402 O OG    . SER B 1 183 ? 103.383 127.151 109.858 1.00 46.73  ?  183 SER C OG    1 
ATOM 3403 N N     . GLN B 1 184 ? 102.530 123.126 110.202 1.00 57.58  ?  184 GLN C N     1 
ATOM 3404 C CA    . GLN B 1 184 ? 102.658 121.991 109.300 1.00 57.58  ?  184 GLN C CA    1 
ATOM 3405 C C     . GLN B 1 184 ? 102.669 122.457 107.851 1.00 57.58  ?  184 GLN C C     1 
ATOM 3406 O O     . GLN B 1 184 ? 102.036 123.455 107.495 1.00 57.58  ?  184 GLN C O     1 
ATOM 3407 C CB    . GLN B 1 184 ? 101.515 121.000 109.520 1.00 57.58  ?  184 GLN C CB    1 
ATOM 3408 C CG    . GLN B 1 184 ? 101.487 120.368 110.897 1.00 57.58  ?  184 GLN C CG    1 
ATOM 3409 C CD    . GLN B 1 184 ? 100.828 121.254 111.932 1.00 57.58  ?  184 GLN C CD    1 
ATOM 3410 O OE1   . GLN B 1 184 ? 101.313 122.345 112.231 1.00 57.58  ?  184 GLN C OE1   1 
ATOM 3411 N NE2   . GLN B 1 184 ? 99.712  120.793 112.482 1.00 57.58  ?  184 GLN C NE2   1 
ATOM 3412 N N     . THR B 1 185 ? 103.398 121.727 107.014 1.00 73.46  ?  185 THR C N     1 
ATOM 3413 C CA    . THR B 1 185 ? 103.481 122.009 105.589 1.00 73.46  ?  185 THR C CA    1 
ATOM 3414 C C     . THR B 1 185 ? 102.633 121.000 104.827 1.00 73.46  ?  185 THR C C     1 
ATOM 3415 O O     . THR B 1 185 ? 102.783 119.789 105.015 1.00 73.46  ?  185 THR C O     1 
ATOM 3416 C CB    . THR B 1 185 ? 104.930 121.957 105.107 1.00 73.46  ?  185 THR C CB    1 
ATOM 3417 O OG1   . THR B 1 185 ? 105.656 123.064 105.655 1.00 73.46  ?  185 THR C OG1   1 
ATOM 3418 C CG2   . THR B 1 185 ? 104.988 122.020 103.594 1.00 73.46  ?  185 THR C CG2   1 
ATOM 3419 N N     . SER B 1 186 ? 101.746 121.501 103.970 1.00 94.49  ?  186 SER C N     1 
ATOM 3420 C CA    . SER B 1 186 ? 100.788 120.666 103.255 1.00 94.49  ?  186 SER C CA    1 
ATOM 3421 C C     . SER B 1 186 ? 101.016 120.615 101.753 1.00 94.49  ?  186 SER C C     1 
ATOM 3422 O O     . SER B 1 186 ? 100.799 119.567 101.141 1.00 94.49  ?  186 SER C O     1 
ATOM 3423 C CB    . SER B 1 186 ? 99.361  121.157 103.526 1.00 94.49  ?  186 SER C CB    1 
ATOM 3424 O OG    . SER B 1 186 ? 99.127  121.299 104.916 1.00 94.49  ?  186 SER C OG    1 
ATOM 3425 N N     . ASN B 1 187 ? 101.448 121.717 101.137 1.00 107.27 ?  187 ASN C N     1 
ATOM 3426 C CA    . ASN B 1 187 ? 101.551 121.790 99.686  1.00 107.27 ?  187 ASN C CA    1 
ATOM 3427 C C     . ASN B 1 187 ? 102.975 121.724 99.155  1.00 107.27 ?  187 ASN C C     1 
ATOM 3428 O O     . ASN B 1 187 ? 103.165 121.301 98.010  1.00 107.27 ?  187 ASN C O     1 
ATOM 3429 C CB    . ASN B 1 187 ? 100.897 123.080 99.171  1.00 107.27 ?  187 ASN C CB    1 
ATOM 3430 C CG    . ASN B 1 187 ? 101.431 124.319 99.860  1.00 107.27 ?  187 ASN C CG    1 
ATOM 3431 O OD1   . ASN B 1 187 ? 101.940 124.249 100.979 1.00 107.27 ?  187 ASN C OD1   1 
ATOM 3432 N ND2   . ASN B 1 187 ? 101.319 125.462 99.194  1.00 107.27 ?  187 ASN C ND2   1 
ATOM 3433 N N     . VAL B 1 188 ? 103.972 122.125 99.940  1.00 109.92 ?  188 VAL C N     1 
ATOM 3434 C CA    . VAL B 1 188 ? 105.353 122.124 99.465  1.00 109.92 ?  188 VAL C CA    1 
ATOM 3435 C C     . VAL B 1 188 ? 105.827 120.677 99.377  1.00 109.92 ?  188 VAL C C     1 
ATOM 3436 O O     . VAL B 1 188 ? 105.932 119.984 100.393 1.00 109.92 ?  188 VAL C O     1 
ATOM 3437 C CB    . VAL B 1 188 ? 106.265 122.955 100.373 1.00 109.92 ?  188 VAL C CB    1 
ATOM 3438 C CG1   . VAL B 1 188 ? 107.650 123.079 99.759  1.00 109.92 ?  188 VAL C CG1   1 
ATOM 3439 C CG2   . VAL B 1 188 ? 105.659 124.328 100.618 1.00 109.92 ?  188 VAL C CG2   1 
ATOM 3440 N N     . ASP B 1 189 ? 106.114 120.218 98.159  1.00 117.03 ?  189 ASP C N     1 
ATOM 3441 C CA    . ASP B 1 189 ? 106.566 118.851 97.939  1.00 117.03 ?  189 ASP C CA    1 
ATOM 3442 C C     . ASP B 1 189 ? 108.046 118.657 98.233  1.00 117.03 ?  189 ASP C C     1 
ATOM 3443 O O     . ASP B 1 189 ? 108.505 117.511 98.272  1.00 117.03 ?  189 ASP C O     1 
ATOM 3444 C CB    . ASP B 1 189 ? 106.275 118.431 96.496  1.00 117.03 ?  189 ASP C CB    1 
ATOM 3445 C CG    . ASP B 1 189 ? 106.773 119.443 95.484  1.00 117.03 ?  189 ASP C CG    1 
ATOM 3446 O OD1   . ASP B 1 189 ? 107.155 120.559 95.895  1.00 117.03 ?  189 ASP C OD1   1 
ATOM 3447 O OD2   . ASP B 1 189 ? 106.785 119.123 94.277  1.00 117.03 -1 189 ASP C OD2   1 
ATOM 3448 N N     . LYS B 1 190 ? 108.800 119.736 98.432  1.00 107.01 ?  190 LYS C N     1 
ATOM 3449 C CA    . LYS B 1 190 ? 110.225 119.613 98.704  1.00 107.01 ?  190 LYS C CA    1 
ATOM 3450 C C     . LYS B 1 190 ? 110.454 118.924 100.042 1.00 107.01 ?  190 LYS C C     1 
ATOM 3451 O O     . LYS B 1 190 ? 109.796 119.238 101.038 1.00 107.01 ?  190 LYS C O     1 
ATOM 3452 C CB    . LYS B 1 190 ? 110.885 120.992 98.695  1.00 107.01 ?  190 LYS C CB    1 
ATOM 3453 C CG    . LYS B 1 190 ? 110.452 121.881 97.540  1.00 107.01 ?  190 LYS C CG    1 
ATOM 3454 C CD    . LYS B 1 190 ? 110.748 121.232 96.197  1.00 107.01 ?  190 LYS C CD    1 
ATOM 3455 C CE    . LYS B 1 190 ? 112.241 121.034 95.994  1.00 107.01 ?  190 LYS C CE    1 
ATOM 3456 N NZ    . LYS B 1 190 ? 112.998 122.301 96.188  1.00 107.01 1  190 LYS C NZ    1 
ATOM 3457 N N     . GLU B 1 191 ? 111.395 117.978 100.061 1.00 99.44  ?  191 GLU C N     1 
ATOM 3458 C CA    . GLU B 1 191 ? 111.680 117.241 101.285 1.00 99.44  ?  191 GLU C CA    1 
ATOM 3459 C C     . GLU B 1 191 ? 112.410 118.089 102.316 1.00 99.44  ?  191 GLU C C     1 
ATOM 3460 O O     . GLU B 1 191 ? 112.365 117.765 103.508 1.00 99.44  ?  191 GLU C O     1 
ATOM 3461 C CB    . GLU B 1 191 ? 112.499 115.990 100.966 1.00 99.44  ?  191 GLU C CB    1 
ATOM 3462 C CG    . GLU B 1 191 ? 111.701 114.884 100.297 1.00 99.44  ?  191 GLU C CG    1 
ATOM 3463 C CD    . GLU B 1 191 ? 110.228 114.926 100.656 1.00 99.44  ?  191 GLU C CD    1 
ATOM 3464 O OE1   . GLU B 1 191 ? 109.888 114.630 101.821 1.00 99.44  ?  191 GLU C OE1   1 
ATOM 3465 O OE2   . GLU B 1 191 ? 109.409 115.256 99.773  1.00 99.44  -1 191 GLU C OE2   1 
ATOM 3466 N N     . GLU B 1 192 ? 113.074 119.162 101.891 1.00 88.43  ?  192 GLU C N     1 
ATOM 3467 C CA    . GLU B 1 192 ? 113.773 120.058 102.800 1.00 88.43  ?  192 GLU C CA    1 
ATOM 3468 C C     . GLU B 1 192 ? 112.877 121.173 103.324 1.00 88.43  ?  192 GLU C C     1 
ATOM 3469 O O     . GLU B 1 192 ? 113.386 122.210 103.764 1.00 88.43  ?  192 GLU C O     1 
ATOM 3470 C CB    . GLU B 1 192 ? 115.005 120.653 102.113 1.00 88.43  ?  192 GLU C CB    1 
ATOM 3471 C CG    . GLU B 1 192 ? 114.747 121.177 100.711 1.00 88.43  ?  192 GLU C CG    1 
ATOM 3472 C CD    . GLU B 1 192 ? 115.006 120.133 99.643  1.00 88.43  ?  192 GLU C CD    1 
ATOM 3473 O OE1   . GLU B 1 192 ? 114.327 119.085 99.658  1.00 88.43  ?  192 GLU C OE1   1 
ATOM 3474 O OE2   . GLU B 1 192 ? 115.889 120.360 98.789  1.00 88.43  -1 192 GLU C OE2   1 
ATOM 3475 N N     . GLU B 1 193 ? 111.558 120.990 103.275 1.00 73.77  ?  193 GLU C N     1 
ATOM 3476 C CA    . GLU B 1 193 ? 110.634 121.982 103.807 1.00 73.77  ?  193 GLU C CA    1 
ATOM 3477 C C     . GLU B 1 193 ? 109.492 121.395 104.622 1.00 73.77  ?  193 GLU C C     1 
ATOM 3478 O O     . GLU B 1 193 ? 108.807 122.159 105.307 1.00 73.77  ?  193 GLU C O     1 
ATOM 3479 C CB    . GLU B 1 193 ? 110.047 122.827 102.668 1.00 73.77  ?  193 GLU C CB    1 
ATOM 3480 C CG    . GLU B 1 193 ? 110.697 124.191 102.516 1.00 73.77  ?  193 GLU C CG    1 
ATOM 3481 C CD    . GLU B 1 193 ? 110.981 124.852 103.850 1.00 73.77  ?  193 GLU C CD    1 
ATOM 3482 O OE1   . GLU B 1 193 ? 110.019 125.111 104.604 1.00 73.77  ?  193 GLU C OE1   1 
ATOM 3483 O OE2   . GLU B 1 193 ? 112.165 125.114 104.145 1.00 73.77  -1 193 GLU C OE2   1 
ATOM 3484 N N     . ALA B 1 194 ? 109.258 120.087 104.577 1.00 58.60  ?  194 ALA C N     1 
ATOM 3485 C CA    . ALA B 1 194 ? 108.137 119.500 105.297 1.00 58.60  ?  194 ALA C CA    1 
ATOM 3486 C C     . ALA B 1 194 ? 108.358 119.576 106.802 1.00 58.60  ?  194 ALA C C     1 
ATOM 3487 O O     . ALA B 1 194 ? 109.474 119.393 107.294 1.00 58.60  ?  194 ALA C O     1 
ATOM 3488 C CB    . ALA B 1 194 ? 107.934 118.048 104.868 1.00 58.60  ?  194 ALA C CB    1 
ATOM 3489 N N     . VAL B 1 195 ? 107.280 119.857 107.533 1.00 42.85  ?  195 VAL C N     1 
ATOM 3490 C CA    . VAL B 1 195 ? 107.316 119.931 108.990 1.00 42.85  ?  195 VAL C CA    1 
ATOM 3491 C C     . VAL B 1 195 ? 106.311 118.920 109.532 1.00 42.85  ?  195 VAL C C     1 
ATOM 3492 O O     . VAL B 1 195 ? 105.654 119.159 110.551 1.00 42.85  ?  195 VAL C O     1 
ATOM 3493 C CB    . VAL B 1 195 ? 107.022 121.358 109.489 1.00 42.85  ?  195 VAL C CB    1 
ATOM 3494 C CG1   . VAL B 1 195 ? 107.459 121.530 110.939 1.00 42.85  ?  195 VAL C CG1   1 
ATOM 3495 C CG2   . VAL B 1 195 ? 107.709 122.382 108.603 1.00 42.85  ?  195 VAL C CG2   1 
ATOM 3496 N N     . THR B 1 196 ? 106.169 117.797 108.831 1.00 38.49  ?  196 THR C N     1 
ATOM 3497 C CA    . THR B 1 196 ? 105.163 116.798 109.176 1.00 38.49  ?  196 THR C CA    1 
ATOM 3498 C C     . THR B 1 196 ? 105.332 116.318 110.613 1.00 38.49  ?  196 THR C C     1 
ATOM 3499 O O     . THR B 1 196 ? 106.446 116.028 111.058 1.00 38.49  ?  196 THR C O     1 
ATOM 3500 C CB    . THR B 1 196 ? 105.256 115.619 108.206 1.00 38.49  ?  196 THR C CB    1 
ATOM 3501 O OG1   . THR B 1 196 ? 104.640 115.973 106.962 1.00 38.49  ?  196 THR C OG1   1 
ATOM 3502 C CG2   . THR B 1 196 ? 104.566 114.388 108.774 1.00 38.49  ?  196 THR C CG2   1 
ATOM 3503 N N     . ILE B 1 197 ? 104.217 116.237 111.336 1.00 42.02  ?  197 ILE C N     1 
ATOM 3504 C CA    . ILE B 1 197 ? 104.194 115.851 112.742 1.00 42.02  ?  197 ILE C CA    1 
ATOM 3505 C C     . ILE B 1 197 ? 103.285 114.639 112.896 1.00 42.02  ?  197 ILE C C     1 
ATOM 3506 O O     . ILE B 1 197 ? 102.226 114.565 112.263 1.00 42.02  ?  197 ILE C O     1 
ATOM 3507 C CB    . ILE B 1 197 ? 103.722 117.013 113.636 1.00 42.02  ?  197 ILE C CB    1 
ATOM 3508 C CG1   . ILE B 1 197 ? 103.620 116.569 115.093 1.00 42.02  ?  197 ILE C CG1   1 
ATOM 3509 C CG2   . ILE B 1 197 ? 102.395 117.567 113.148 1.00 42.02  ?  197 ILE C CG2   1 
ATOM 3510 C CD1   . ILE B 1 197 ? 103.289 117.692 116.038 1.00 42.02  ?  197 ILE C CD1   1 
ATOM 3511 N N     . GLU B 1 198 ? 103.706 113.687 113.724 1.00 52.24  ?  198 GLU C N     1 
ATOM 3512 C CA    . GLU B 1 198 ? 102.960 112.460 113.970 1.00 52.24  ?  198 GLU C CA    1 
ATOM 3513 C C     . GLU B 1 198 ? 102.488 112.434 115.418 1.00 52.24  ?  198 GLU C C     1 
ATOM 3514 O O     . GLU B 1 198 ? 103.271 112.701 116.335 1.00 52.24  ?  198 GLU C O     1 
ATOM 3515 C CB    . GLU B 1 198 ? 103.821 111.232 113.671 1.00 52.24  ?  198 GLU C CB    1 
ATOM 3516 C CG    . GLU B 1 198 ? 103.193 109.918 114.088 1.00 52.24  ?  198 GLU C CG    1 
ATOM 3517 C CD    . GLU B 1 198 ? 101.844 109.694 113.441 1.00 52.24  ?  198 GLU C CD    1 
ATOM 3518 O OE1   . GLU B 1 198 ? 101.809 109.161 112.312 1.00 52.24  ?  198 GLU C OE1   1 
ATOM 3519 O OE2   . GLU B 1 198 ? 100.818 110.050 114.058 1.00 52.24  -1 198 GLU C OE2   1 
ATOM 3520 N N     . MET B 1 199 ? 101.214 112.109 115.620 1.00 63.73  ?  199 MET C N     1 
ATOM 3521 C CA    . MET B 1 199 ? 100.590 112.123 116.938 1.00 63.73  ?  199 MET C CA    1 
ATOM 3522 C C     . MET B 1 199 ? 99.968  110.781 117.286 1.00 63.73  ?  199 MET C C     1 
ATOM 3523 O O     . MET B 1 199 ? 99.270  110.177 116.465 1.00 63.73  ?  199 MET C O     1 
ATOM 3524 C CB    . MET B 1 199 ? 99.533  113.225 117.031 1.00 63.73  ?  199 MET C CB    1 
ATOM 3525 C CG    . MET B 1 199 ? 100.023 114.430 117.785 1.00 63.73  ?  199 MET C CG    1 
ATOM 3526 S SD    . MET B 1 199 ? 100.683 113.808 119.341 1.00 63.73  ?  199 MET C SD    1 
ATOM 3527 C CE    . MET B 1 199 ? 102.250 114.635 119.414 1.00 63.73  ?  199 MET C CE    1 
ATOM 3528 N N     . ASN B 1 200 ? 100.228 110.331 118.500 1.00 72.13  ?  200 ASN C N     1 
ATOM 3529 C CA    . ASN B 1 200 ? 99.529  109.234 119.155 1.00 72.13  ?  200 ASN C CA    1 
ATOM 3530 C C     . ASN B 1 200 ? 99.005  109.627 120.527 1.00 72.13  ?  200 ASN C C     1 
ATOM 3531 O O     . ASN B 1 200 ? 97.903  109.217 120.897 1.00 72.13  ?  200 ASN C O     1 
ATOM 3532 C CB    . ASN B 1 200 ? 100.454 108.017 119.279 1.00 72.13  ?  200 ASN C CB    1 
ATOM 3533 C CG    . ASN B 1 200 ? 99.690  106.727 119.486 1.00 72.13  ?  200 ASN C CG    1 
ATOM 3534 O OD1   . ASN B 1 200 ? 98.469  106.685 119.337 1.00 72.13  ?  200 ASN C OD1   1 
ATOM 3535 N ND2   . ASN B 1 200 ? 100.406 105.665 119.838 1.00 72.13  ?  200 ASN C ND2   1 
ATOM 3536 N N     . GLU B 1 201 ? 99.763  110.427 121.284 1.00 72.59  ?  201 GLU C N     1 
ATOM 3537 C CA    . GLU B 1 201 ? 99.384  110.954 122.588 1.00 72.59  ?  201 GLU C CA    1 
ATOM 3538 C C     . GLU B 1 201 ? 100.115 112.272 122.783 1.00 72.59  ?  201 GLU C C     1 
ATOM 3539 O O     . GLU B 1 201 ? 101.293 112.376 122.413 1.00 72.59  ?  201 GLU C O     1 
ATOM 3540 C CB    . GLU B 1 201 ? 99.731  110.001 123.737 1.00 72.59  ?  201 GLU C CB    1 
ATOM 3541 C CG    . GLU B 1 201 ? 98.791  108.821 123.897 1.00 72.59  ?  201 GLU C CG    1 
ATOM 3542 C CD    . GLU B 1 201 ? 99.256  107.599 123.133 1.00 72.59  ?  201 GLU C CD    1 
ATOM 3543 O OE1   . GLU B 1 201 ? 100.344 107.656 122.524 1.00 72.59  ?  201 GLU C OE1   1 
ATOM 3544 O OE2   . GLU B 1 201 ? 98.533  106.581 123.141 1.00 72.59  -1 201 GLU C OE2   1 
ATOM 3545 N N     . PRO B 1 202 ? 99.460  113.286 123.345 1.00 62.25  ?  202 PRO C N     1 
ATOM 3546 C CA    . PRO B 1 202 ? 100.153 114.555 123.600 1.00 62.25  ?  202 PRO C CA    1 
ATOM 3547 C C     . PRO B 1 202 ? 101.283 114.371 124.601 1.00 62.25  ?  202 PRO C C     1 
ATOM 3548 O O     . PRO B 1 202 ? 101.186 113.573 125.535 1.00 62.25  ?  202 PRO C O     1 
ATOM 3549 C CB    . PRO B 1 202 ? 99.050  115.466 124.155 1.00 62.25  ?  202 PRO C CB    1 
ATOM 3550 C CG    . PRO B 1 202 ? 97.758  114.763 123.880 1.00 62.25  ?  202 PRO C CG    1 
ATOM 3551 C CD    . PRO B 1 202 ? 98.060  113.308 123.796 1.00 62.25  ?  202 PRO C CD    1 
ATOM 3552 N N     . VAL B 1 203 ? 102.369 115.119 124.396 1.00 49.66  ?  203 VAL C N     1 
ATOM 3553 C CA    . VAL B 1 203 ? 103.545 115.040 125.251 1.00 49.66  ?  203 VAL C CA    1 
ATOM 3554 C C     . VAL B 1 203 ? 104.031 116.444 125.579 1.00 49.66  ?  203 VAL C C     1 
ATOM 3555 O O     . VAL B 1 203 ? 103.703 117.418 124.899 1.00 49.66  ?  203 VAL C O     1 
ATOM 3556 C CB    . VAL B 1 203 ? 104.688 114.227 124.606 1.00 49.66  ?  203 VAL C CB    1 
ATOM 3557 C CG1   . VAL B 1 203 ? 104.266 112.782 124.404 1.00 49.66  ?  203 VAL C CG1   1 
ATOM 3558 C CG2   . VAL B 1 203 ? 105.102 114.858 123.291 1.00 49.66  ?  203 VAL C CG2   1 
ATOM 3559 N N     . GLN B 1 204 ? 104.826 116.533 126.642 1.00 47.24  ?  204 GLN C N     1 
ATOM 3560 C CA    . GLN B 1 204 ? 105.429 117.795 127.064 1.00 47.24  ?  204 GLN C CA    1 
ATOM 3561 C C     . GLN B 1 204 ? 106.621 117.462 127.944 1.00 47.24  ?  204 GLN C C     1 
ATOM 3562 O O     . GLN B 1 204 ? 106.459 116.813 128.982 1.00 47.24  ?  204 GLN C O     1 
ATOM 3563 C CB    . GLN B 1 204 ? 104.419 118.664 127.812 1.00 47.24  ?  204 GLN C CB    1 
ATOM 3564 C CG    . GLN B 1 204 ? 105.027 119.568 128.869 1.00 47.24  ?  204 GLN C CG    1 
ATOM 3565 C CD    . GLN B 1 204 ? 104.209 120.820 129.101 1.00 47.24  ?  204 GLN C CD    1 
ATOM 3566 O OE1   . GLN B 1 204 ? 103.032 120.880 128.745 1.00 47.24  ?  204 GLN C OE1   1 
ATOM 3567 N NE2   . GLN B 1 204 ? 104.825 121.827 129.706 1.00 47.24  ?  204 GLN C NE2   1 
ATOM 3568 N N     . LEU B 1 205 ? 107.815 117.882 127.527 1.00 35.73  ?  205 LEU C N     1 
ATOM 3569 C CA    . LEU B 1 205 ? 109.031 117.523 128.245 1.00 35.73  ?  205 LEU C CA    1 
ATOM 3570 C C     . LEU B 1 205 ? 109.940 118.727 128.445 1.00 35.73  ?  205 LEU C C     1 
ATOM 3571 O O     . LEU B 1 205 ? 109.543 119.864 128.174 1.00 35.73  ?  205 LEU C O     1 
ATOM 3572 C CB    . LEU B 1 205 ? 109.779 116.416 127.501 1.00 35.73  ?  205 LEU C CB    1 
ATOM 3573 C CG    . LEU B 1 205 ? 108.960 115.179 127.131 1.00 35.73  ?  205 LEU C CG    1 
ATOM 3574 C CD1   . LEU B 1 205 ? 108.677 115.152 125.641 1.00 35.73  ?  205 LEU C CD1   1 
ATOM 3575 C CD2   . LEU B 1 205 ? 109.671 113.910 127.568 1.00 35.73  ?  205 LEU C CD2   1 
ATOM 3576 N N     . THR B 1 206 ? 111.158 118.487 128.922 1.00 36.89  ?  206 THR C N     1 
ATOM 3577 C CA    . THR B 1 206 ? 112.111 119.558 129.182 1.00 36.89  ?  206 THR C CA    1 
ATOM 3578 C C     . THR B 1 206 ? 113.521 119.012 129.034 1.00 36.89  ?  206 THR C C     1 
ATOM 3579 O O     . THR B 1 206 ? 113.850 117.982 129.627 1.00 36.89  ?  206 THR C O     1 
ATOM 3580 C CB    . THR B 1 206 ? 111.921 120.138 130.585 1.00 36.89  ?  206 THR C CB    1 
ATOM 3581 O OG1   . THR B 1 206 ? 110.580 120.621 130.728 1.00 36.89  ?  206 THR C OG1   1 
ATOM 3582 C CG2   . THR B 1 206 ? 112.896 121.275 130.823 1.00 36.89  ?  206 THR C CG2   1 
ATOM 3583 N N     . PHE B 1 207 ? 114.349 119.705 128.257 1.00 22.17  ?  207 PHE C N     1 
ATOM 3584 C CA    . PHE B 1 207 ? 115.713 119.274 128.000 1.00 22.17  ?  207 PHE C CA    1 
ATOM 3585 C C     . PHE B 1 207 ? 116.662 120.456 128.127 1.00 22.17  ?  207 PHE C C     1 
ATOM 3586 O O     . PHE B 1 207 ? 116.275 121.613 127.948 1.00 22.17  ?  207 PHE C O     1 
ATOM 3587 C CB    . PHE B 1 207 ? 115.851 118.647 126.610 1.00 22.17  ?  207 PHE C CB    1 
ATOM 3588 C CG    . PHE B 1 207 ? 114.783 117.648 126.289 1.00 22.17  ?  207 PHE C CG    1 
ATOM 3589 C CD1   . PHE B 1 207 ? 114.934 116.320 126.633 1.00 22.17  ?  207 PHE C CD1   1 
ATOM 3590 C CD2   . PHE B 1 207 ? 113.628 118.038 125.642 1.00 22.17  ?  207 PHE C CD2   1 
ATOM 3591 C CE1   . PHE B 1 207 ? 113.953 115.401 126.338 1.00 22.17  ?  207 PHE C CE1   1 
ATOM 3592 C CE2   . PHE B 1 207 ? 112.644 117.122 125.346 1.00 22.17  ?  207 PHE C CE2   1 
ATOM 3593 C CZ    . PHE B 1 207 ? 112.808 115.802 125.694 1.00 22.17  ?  207 PHE C CZ    1 
ATOM 3594 N N     . ALA B 1 208 ? 117.916 120.150 128.444 1.00 33.30  ?  208 ALA C N     1 
ATOM 3595 C CA    . ALA B 1 208 ? 118.936 121.185 128.531 1.00 33.30  ?  208 ALA C CA    1 
ATOM 3596 C C     . ALA B 1 208 ? 119.302 121.669 127.136 1.00 33.30  ?  208 ALA C C     1 
ATOM 3597 O O     . ALA B 1 208 ? 119.538 120.864 126.231 1.00 33.30  ?  208 ALA C O     1 
ATOM 3598 C CB    . ALA B 1 208 ? 120.172 120.654 129.251 1.00 33.30  ?  208 ALA C CB    1 
ATOM 3599 N N     . LEU B 1 209 ? 119.352 122.989 126.960 1.00 32.54  ?  209 LEU C N     1 
ATOM 3600 C CA    . LEU B 1 209 ? 119.607 123.545 125.638 1.00 32.54  ?  209 LEU C CA    1 
ATOM 3601 C C     . LEU B 1 209 ? 121.063 123.416 125.217 1.00 32.54  ?  209 LEU C C     1 
ATOM 3602 O O     . LEU B 1 209 ? 121.346 123.409 124.015 1.00 32.54  ?  209 LEU C O     1 
ATOM 3603 C CB    . LEU B 1 209 ? 119.184 125.010 125.592 1.00 32.54  ?  209 LEU C CB    1 
ATOM 3604 C CG    . LEU B 1 209 ? 117.765 125.239 125.077 1.00 32.54  ?  209 LEU C CG    1 
ATOM 3605 C CD1   . LEU B 1 209 ? 117.467 126.719 125.002 1.00 32.54  ?  209 LEU C CD1   1 
ATOM 3606 C CD2   . LEU B 1 209 ? 117.579 124.583 123.725 1.00 32.54  ?  209 LEU C CD2   1 
ATOM 3607 N N     . ARG B 1 210 ? 121.991 123.323 126.170 1.00 37.10  ?  210 ARG C N     1 
ATOM 3608 C CA    . ARG B 1 210 ? 123.397 123.167 125.812 1.00 37.10  ?  210 ARG C CA    1 
ATOM 3609 C C     . ARG B 1 210 ? 123.629 121.863 125.060 1.00 37.10  ?  210 ARG C C     1 
ATOM 3610 O O     . ARG B 1 210 ? 124.358 121.830 124.059 1.00 37.10  ?  210 ARG C O     1 
ATOM 3611 C CB    . ARG B 1 210 ? 124.261 123.233 127.070 1.00 37.10  ?  210 ARG C CB    1 
ATOM 3612 C CG    . ARG B 1 210 ? 125.592 122.520 126.961 1.00 37.10  ?  210 ARG C CG    1 
ATOM 3613 C CD    . ARG B 1 210 ? 126.268 122.400 128.321 1.00 37.10  ?  210 ARG C CD    1 
ATOM 3614 N NE    . ARG B 1 210 ? 125.522 121.552 129.244 1.00 37.10  ?  210 ARG C NE    1 
ATOM 3615 C CZ    . ARG B 1 210 ? 124.741 122.004 130.216 1.00 37.10  ?  210 ARG C CZ    1 
ATOM 3616 N NH1   . ARG B 1 210 ? 124.574 123.300 130.422 1.00 37.10  1  210 ARG C NH1   1 
ATOM 3617 N NH2   . ARG B 1 210 ? 124.114 121.134 131.002 1.00 37.10  ?  210 ARG C NH2   1 
ATOM 3618 N N     . TYR B 1 211 ? 123.002 120.778 125.514 1.00 37.10  ?  211 TYR C N     1 
ATOM 3619 C CA    . TYR B 1 211 ? 123.154 119.506 124.821 1.00 37.10  ?  211 TYR C CA    1 
ATOM 3620 C C     . TYR B 1 211 ? 122.495 119.532 123.449 1.00 37.10  ?  211 TYR C C     1 
ATOM 3621 O O     . TYR B 1 211 ? 123.001 118.908 122.513 1.00 37.10  ?  211 TYR C O     1 
ATOM 3622 C CB    . TYR B 1 211 ? 122.589 118.375 125.675 1.00 37.10  ?  211 TYR C CB    1 
ATOM 3623 C CG    . TYR B 1 211 ? 123.485 118.025 126.836 1.00 37.10  ?  211 TYR C CG    1 
ATOM 3624 C CD1   . TYR B 1 211 ? 124.676 117.346 126.636 1.00 37.10  ?  211 TYR C CD1   1 
ATOM 3625 C CD2   . TYR B 1 211 ? 123.151 118.394 128.129 1.00 37.10  ?  211 TYR C CD2   1 
ATOM 3626 C CE1   . TYR B 1 211 ? 125.503 117.032 127.693 1.00 37.10  ?  211 TYR C CE1   1 
ATOM 3627 C CE2   . TYR B 1 211 ? 123.971 118.085 129.192 1.00 37.10  ?  211 TYR C CE2   1 
ATOM 3628 C CZ    . TYR B 1 211 ? 125.146 117.405 128.968 1.00 37.10  ?  211 TYR C CZ    1 
ATOM 3629 O OH    . TYR B 1 211 ? 125.964 117.095 130.027 1.00 37.10  ?  211 TYR C OH    1 
ATOM 3630 N N     . LEU B 1 212 ? 121.379 120.248 123.301 1.00 29.70  ?  212 LEU C N     1 
ATOM 3631 C CA    . LEU B 1 212 ? 120.775 120.384 121.981 1.00 29.70  ?  212 LEU C CA    1 
ATOM 3632 C C     . LEU B 1 212 ? 121.677 121.177 121.042 1.00 29.70  ?  212 LEU C C     1 
ATOM 3633 O O     . LEU B 1 212 ? 121.782 120.857 119.851 1.00 29.70  ?  212 LEU C O     1 
ATOM 3634 C CB    . LEU B 1 212 ? 119.402 121.039 122.097 1.00 29.70  ?  212 LEU C CB    1 
ATOM 3635 C CG    . LEU B 1 212 ? 118.308 120.155 122.696 1.00 29.70  ?  212 LEU C CG    1 
ATOM 3636 C CD1   . LEU B 1 212 ? 116.937 120.745 122.436 1.00 29.70  ?  212 LEU C CD1   1 
ATOM 3637 C CD2   . LEU B 1 212 ? 118.397 118.749 122.139 1.00 29.70  ?  212 LEU C CD2   1 
ATOM 3638 N N     . ASN B 1 213 ? 122.333 122.218 121.559 1.00 31.60  ?  213 ASN C N     1 
ATOM 3639 C CA    . ASN B 1 213 ? 123.289 122.960 120.745 1.00 31.60  ?  213 ASN C CA    1 
ATOM 3640 C C     . ASN B 1 213 ? 124.450 122.072 120.322 1.00 31.60  ?  213 ASN C C     1 
ATOM 3641 O O     . ASN B 1 213 ? 124.918 122.150 119.181 1.00 31.60  ?  213 ASN C O     1 
ATOM 3642 C CB    . ASN B 1 213 ? 123.800 124.178 121.509 1.00 31.60  ?  213 ASN C CB    1 
ATOM 3643 C CG    . ASN B 1 213 ? 122.789 125.299 121.555 1.00 31.60  ?  213 ASN C CG    1 
ATOM 3644 O OD1   . ASN B 1 213 ? 122.861 126.180 122.410 1.00 31.60  ?  213 ASN C OD1   1 
ATOM 3645 N ND2   . ASN B 1 213 ? 121.833 125.271 120.634 1.00 31.60  ?  213 ASN C ND2   1 
ATOM 3646 N N     . PHE B 1 214 ? 124.936 121.226 121.234 1.00 37.63  ?  214 PHE C N     1 
ATOM 3647 C CA    . PHE B 1 214 ? 125.975 120.269 120.865 1.00 37.63  ?  214 PHE C CA    1 
ATOM 3648 C C     . PHE B 1 214 ? 125.479 119.306 119.794 1.00 37.63  ?  214 PHE C C     1 
ATOM 3649 O O     . PHE B 1 214 ? 126.213 118.972 118.859 1.00 37.63  ?  214 PHE C O     1 
ATOM 3650 C CB    . PHE B 1 214 ? 126.443 119.493 122.094 1.00 37.63  ?  214 PHE C CB    1 
ATOM 3651 C CG    . PHE B 1 214 ? 127.393 120.253 122.965 1.00 37.63  ?  214 PHE C CG    1 
ATOM 3652 C CD1   . PHE B 1 214 ? 128.177 121.262 122.439 1.00 37.63  ?  214 PHE C CD1   1 
ATOM 3653 C CD2   . PHE B 1 214 ? 127.506 119.955 124.310 1.00 37.63  ?  214 PHE C CD2   1 
ATOM 3654 C CE1   . PHE B 1 214 ? 129.052 121.962 123.239 1.00 37.63  ?  214 PHE C CE1   1 
ATOM 3655 C CE2   . PHE B 1 214 ? 128.379 120.650 125.115 1.00 37.63  ?  214 PHE C CE2   1 
ATOM 3656 C CZ    . PHE B 1 214 ? 129.154 121.656 124.579 1.00 37.63  ?  214 PHE C CZ    1 
ATOM 3657 N N     . PHE B 1 215 ? 124.235 118.844 119.924 1.00 29.86  ?  215 PHE C N     1 
ATOM 3658 C CA    . PHE B 1 215 ? 123.682 117.896 118.963 1.00 29.86  ?  215 PHE C CA    1 
ATOM 3659 C C     . PHE B 1 215 ? 123.579 118.510 117.575 1.00 29.86  ?  215 PHE C C     1 
ATOM 3660 O O     . PHE B 1 215 ? 123.884 117.854 116.574 1.00 29.86  ?  215 PHE C O     1 
ATOM 3661 C CB    . PHE B 1 215 ? 122.307 117.418 119.427 1.00 29.86  ?  215 PHE C CB    1 
ATOM 3662 C CG    . PHE B 1 215 ? 122.351 116.440 120.563 1.00 29.86  ?  215 PHE C CG    1 
ATOM 3663 C CD1   . PHE B 1 215 ? 123.553 116.068 121.134 1.00 29.86  ?  215 PHE C CD1   1 
ATOM 3664 C CD2   . PHE B 1 215 ? 121.185 115.892 121.059 1.00 29.86  ?  215 PHE C CD2   1 
ATOM 3665 C CE1   . PHE B 1 215 ? 123.589 115.170 122.176 1.00 29.86  ?  215 PHE C CE1   1 
ATOM 3666 C CE2   . PHE B 1 215 ? 121.217 114.993 122.100 1.00 29.86  ?  215 PHE C CE2   1 
ATOM 3667 C CZ    . PHE B 1 215 ? 122.420 114.632 122.659 1.00 29.86  ?  215 PHE C CZ    1 
ATOM 3668 N N     . THR B 1 216 ? 123.154 119.765 117.495 1.00 33.70  ?  216 THR C N     1 
ATOM 3669 C CA    . THR B 1 216 ? 122.917 120.380 116.187 1.00 33.70  ?  216 THR C CA    1 
ATOM 3670 C C     . THR B 1 216 ? 124.195 120.669 115.408 1.00 33.70  ?  216 THR C C     1 
ATOM 3671 O O     . THR B 1 216 ? 124.090 121.313 114.360 1.00 33.70  ?  216 THR C O     1 
ATOM 3672 C CB    . THR B 1 216 ? 122.118 121.673 116.343 1.00 33.70  ?  216 THR C CB    1 
ATOM 3673 O OG1   . THR B 1 216 ? 122.707 122.480 117.370 1.00 33.70  ?  216 THR C OG1   1 
ATOM 3674 C CG2   . THR B 1 216 ? 120.678 121.361 116.710 1.00 33.70  ?  216 THR C CG2   1 
ATOM 3675 N N     . LYS B 1 217 ? 125.381 120.246 115.849 1.00 33.26  ?  217 LYS C N     1 
ATOM 3676 C CA    . LYS B 1 217 ? 126.586 120.468 115.060 1.00 33.26  ?  217 LYS C CA    1 
ATOM 3677 C C     . LYS B 1 217 ? 126.608 119.636 113.786 1.00 33.26  ?  217 LYS C C     1 
ATOM 3678 O O     . LYS B 1 217 ? 127.369 119.955 112.867 1.00 33.26  ?  217 LYS C O     1 
ATOM 3679 C CB    . LYS B 1 217 ? 127.829 120.161 115.894 1.00 33.26  ?  217 LYS C CB    1 
ATOM 3680 C CG    . LYS B 1 217 ? 128.096 121.158 117.005 1.00 33.26  ?  217 LYS C CG    1 
ATOM 3681 C CD    . LYS B 1 217 ? 128.756 122.415 116.472 1.00 33.26  ?  217 LYS C CD    1 
ATOM 3682 C CE    . LYS B 1 217 ? 129.096 123.372 117.602 1.00 33.26  ?  217 LYS C CE    1 
ATOM 3683 N NZ    . LYS B 1 217 ? 129.775 124.599 117.105 1.00 33.26  1  217 LYS C NZ    1 
ATOM 3684 N N     . ALA B 1 218 ? 125.798 118.582 113.708 1.00 31.82  ?  218 ALA C N     1 
ATOM 3685 C CA    . ALA B 1 218 ? 125.751 117.714 112.541 1.00 31.82  ?  218 ALA C CA    1 
ATOM 3686 C C     . ALA B 1 218 ? 124.762 118.195 111.489 1.00 31.82  ?  218 ALA C C     1 
ATOM 3687 O O     . ALA B 1 218 ? 124.283 117.387 110.688 1.00 31.82  ?  218 ALA C O     1 
ATOM 3688 C CB    . ALA B 1 218 ? 125.414 116.283 112.960 1.00 31.82  ?  218 ALA C CB    1 
ATOM 3689 N N     . THR B 1 219 ? 124.439 119.487 111.483 1.00 28.31  ?  219 THR C N     1 
ATOM 3690 C CA    . THR B 1 219 ? 123.522 120.018 110.479 1.00 28.31  ?  219 THR C CA    1 
ATOM 3691 C C     . THR B 1 219 ? 123.994 119.806 109.042 1.00 28.31  ?  219 THR C C     1 
ATOM 3692 O O     . THR B 1 219 ? 123.161 119.409 108.208 1.00 28.31  ?  219 THR C O     1 
ATOM 3693 C CB    . THR B 1 219 ? 123.266 121.505 110.755 1.00 28.31  ?  219 THR C CB    1 
ATOM 3694 O OG1   . THR B 1 219 ? 122.530 121.643 111.976 1.00 28.31  ?  219 THR C OG1   1 
ATOM 3695 C CG2   . THR B 1 219 ? 122.471 122.132 109.624 1.00 28.31  ?  219 THR C CG2   1 
ATOM 3696 N N     . PRO B 1 220 ? 125.262 120.032 108.677 1.00 26.99  ?  220 PRO C N     1 
ATOM 3697 C CA    . PRO B 1 220 ? 125.653 119.836 107.270 1.00 26.99  ?  220 PRO C CA    1 
ATOM 3698 C C     . PRO B 1 220 ? 125.494 118.409 106.780 1.00 26.99  ?  220 PRO C C     1 
ATOM 3699 O O     . PRO B 1 220 ? 125.504 118.187 105.564 1.00 26.99  ?  220 PRO C O     1 
ATOM 3700 C CB    . PRO B 1 220 ? 127.125 120.269 107.248 1.00 26.99  ?  220 PRO C CB    1 
ATOM 3701 C CG    . PRO B 1 220 ? 127.283 121.145 108.427 1.00 26.99  ?  220 PRO C CG    1 
ATOM 3702 C CD    . PRO B 1 220 ? 126.385 120.567 109.467 1.00 26.99  ?  220 PRO C CD    1 
ATOM 3703 N N     . LEU B 1 221 ? 125.361 117.435 107.683 1.00 27.48  ?  221 LEU C N     1 
ATOM 3704 C CA    . LEU B 1 221 ? 125.246 116.043 107.261 1.00 27.48  ?  221 LEU C CA    1 
ATOM 3705 C C     . LEU B 1 221 ? 123.998 115.813 106.420 1.00 27.48  ?  221 LEU C C     1 
ATOM 3706 O O     . LEU B 1 221 ? 124.050 115.119 105.398 1.00 27.48  ?  221 LEU C O     1 
ATOM 3707 C CB    . LEU B 1 221 ? 125.240 115.129 108.483 1.00 27.48  ?  221 LEU C CB    1 
ATOM 3708 C CG    . LEU B 1 221 ? 126.484 114.267 108.668 1.00 27.48  ?  221 LEU C CG    1 
ATOM 3709 C CD1   . LEU B 1 221 ? 126.344 113.401 109.903 1.00 27.48  ?  221 LEU C CD1   1 
ATOM 3710 C CD2   . LEU B 1 221 ? 126.714 113.417 107.436 1.00 27.48  ?  221 LEU C CD2   1 
ATOM 3711 N N     . SER B 1 222 ? 122.867 116.382 106.830 1.00 29.31  ?  222 SER C N     1 
ATOM 3712 C CA    . SER B 1 222 ? 121.621 116.194 106.103 1.00 29.31  ?  222 SER C CA    1 
ATOM 3713 C C     . SER B 1 222 ? 120.699 117.371 106.372 1.00 29.31  ?  222 SER C C     1 
ATOM 3714 O O     . SER B 1 222 ? 120.862 118.105 107.349 1.00 29.31  ?  222 SER C O     1 
ATOM 3715 C CB    . SER B 1 222 ? 120.935 114.881 106.491 1.00 29.31  ?  222 SER C CB    1 
ATOM 3716 O OG    . SER B 1 222 ? 119.706 114.733 105.804 1.00 29.31  ?  222 SER C OG    1 
ATOM 3717 N N     . SER B 1 223 ? 119.714 117.536 105.491 1.00 31.23  ?  223 SER C N     1 
ATOM 3718 C CA    . SER B 1 223 ? 118.799 118.666 105.576 1.00 31.23  ?  223 SER C CA    1 
ATOM 3719 C C     . SER B 1 223 ? 117.613 118.409 106.493 1.00 31.23  ?  223 SER C C     1 
ATOM 3720 O O     . SER B 1 223 ? 117.058 119.362 107.051 1.00 31.23  ?  223 SER C O     1 
ATOM 3721 C CB    . SER B 1 223 ? 118.287 119.034 104.181 1.00 31.23  ?  223 SER C CB    1 
ATOM 3722 O OG    . SER B 1 223 ? 117.528 117.975 103.627 1.00 31.23  ?  223 SER C OG    1 
ATOM 3723 N N     . THR B 1 224 ? 117.209 117.155 106.667 1.00 35.38  ?  224 THR C N     1 
ATOM 3724 C CA    . THR B 1 224 ? 116.031 116.809 107.450 1.00 35.38  ?  224 THR C CA    1 
ATOM 3725 C C     . THR B 1 224 ? 116.450 116.104 108.732 1.00 35.38  ?  224 THR C C     1 
ATOM 3726 O O     . THR B 1 224 ? 117.209 115.131 108.691 1.00 35.38  ?  224 THR C O     1 
ATOM 3727 C CB    . THR B 1 224 ? 115.083 115.916 106.652 1.00 35.38  ?  224 THR C CB    1 
ATOM 3728 O OG1   . THR B 1 224 ? 115.681 114.627 106.473 1.00 35.38  ?  224 THR C OG1   1 
ATOM 3729 C CG2   . THR B 1 224 ? 114.802 116.530 105.293 1.00 35.38  ?  224 THR C CG2   1 
ATOM 3730 N N     . VAL B 1 225 ? 115.948 116.594 109.861 1.00 35.09  ?  225 VAL C N     1 
ATOM 3731 C CA    . VAL B 1 225 ? 116.222 116.026 111.175 1.00 35.09  ?  225 VAL C CA    1 
ATOM 3732 C C     . VAL B 1 225 ? 114.920 115.479 111.740 1.00 35.09  ?  225 VAL C C     1 
ATOM 3733 O O     . VAL B 1 225 ? 113.884 116.152 111.696 1.00 35.09  ?  225 VAL C O     1 
ATOM 3734 C CB    . VAL B 1 225 ? 116.848 117.066 112.119 1.00 35.09  ?  225 VAL C CB    1 
ATOM 3735 C CG1   . VAL B 1 225 ? 116.015 118.329 112.155 1.00 35.09  ?  225 VAL C CG1   1 
ATOM 3736 C CG2   . VAL B 1 225 ? 116.980 116.497 113.509 1.00 35.09  ?  225 VAL C CG2   1 
ATOM 3737 N N     . THR B 1 226 ? 114.968 114.254 112.249 1.00 54.26  ?  226 THR C N     1 
ATOM 3738 C CA    . THR B 1 226 ? 113.801 113.579 112.796 1.00 54.26  ?  226 THR C CA    1 
ATOM 3739 C C     . THR B 1 226 ? 113.907 113.534 114.313 1.00 54.26  ?  226 THR C C     1 
ATOM 3740 O O     . THR B 1 226 ? 114.938 113.122 114.854 1.00 54.26  ?  226 THR C O     1 
ATOM 3741 C CB    . THR B 1 226 ? 113.676 112.162 112.236 1.00 54.26  ?  226 THR C CB    1 
ATOM 3742 O OG1   . THR B 1 226 ? 113.460 112.224 110.822 1.00 54.26  ?  226 THR C OG1   1 
ATOM 3743 C CG2   . THR B 1 226 ? 112.517 111.431 112.886 1.00 54.26  ?  226 THR C CG2   1 
ATOM 3744 N N     . LEU B 1 227 ? 112.848 113.959 114.993 1.00 54.26  ?  227 LEU C N     1 
ATOM 3745 C CA    . LEU B 1 227 ? 112.780 113.934 116.446 1.00 54.26  ?  227 LEU C CA    1 
ATOM 3746 C C     . LEU B 1 227 ? 111.722 112.935 116.883 1.00 54.26  ?  227 LEU C C     1 
ATOM 3747 O O     . LEU B 1 227 ? 110.597 112.952 116.373 1.00 54.26  ?  227 LEU C O     1 
ATOM 3748 C CB    . LEU B 1 227 ? 112.459 115.318 117.008 1.00 54.26  ?  227 LEU C CB    1 
ATOM 3749 C CG    . LEU B 1 227 ? 113.647 116.247 117.230 1.00 54.26  ?  227 LEU C CG    1 
ATOM 3750 C CD1   . LEU B 1 227 ? 114.006 116.957 115.945 1.00 54.26  ?  227 LEU C CD1   1 
ATOM 3751 C CD2   . LEU B 1 227 ? 113.331 117.247 118.322 1.00 54.26  ?  227 LEU C CD2   1 
ATOM 3752 N N     . SER B 1 228 ? 112.084 112.068 117.822 1.00 46.38  ?  228 SER C N     1 
ATOM 3753 C CA    . SER B 1 228 ? 111.164 111.085 118.372 1.00 46.38  ?  228 SER C CA    1 
ATOM 3754 C C     . SER B 1 228 ? 111.263 111.123 119.887 1.00 46.38  ?  228 SER C C     1 
ATOM 3755 O O     . SER B 1 228 ? 112.367 111.145 120.438 1.00 46.38  ?  228 SER C O     1 
ATOM 3756 C CB    . SER B 1 228 ? 111.475 109.682 117.851 1.00 46.38  ?  228 SER C CB    1 
ATOM 3757 O OG    . SER B 1 228 ? 111.697 109.702 116.453 1.00 46.38  ?  228 SER C OG    1 
ATOM 3758 N N     . MET B 1 229 ? 110.114 111.136 120.554 1.00 43.69  ?  229 MET C N     1 
ATOM 3759 C CA    . MET B 1 229 ? 110.087 111.181 122.007 1.00 43.69  ?  229 MET C CA    1 
ATOM 3760 C C     . MET B 1 229 ? 108.727 110.705 122.490 1.00 43.69  ?  229 MET C C     1 
ATOM 3761 O O     . MET B 1 229 ? 107.751 110.685 121.737 1.00 43.69  ?  229 MET C O     1 
ATOM 3762 C CB    . MET B 1 229 ? 110.387 112.588 122.529 1.00 43.69  ?  229 MET C CB    1 
ATOM 3763 C CG    . MET B 1 229 ? 109.275 113.591 122.292 1.00 43.69  ?  229 MET C CG    1 
ATOM 3764 S SD    . MET B 1 229 ? 109.896 115.281 122.229 1.00 43.69  ?  229 MET C SD    1 
ATOM 3765 C CE    . MET B 1 229 ? 108.595 116.092 121.309 1.00 43.69  ?  229 MET C CE    1 
ATOM 3766 N N     . SER B 1 230 ? 108.681 110.320 123.759 1.00 45.92  ?  230 SER C N     1 
ATOM 3767 C CA    . SER B 1 230 ? 107.448 109.870 124.388 1.00 45.92  ?  230 SER C CA    1 
ATOM 3768 C C     . SER B 1 230 ? 107.561 110.149 125.885 1.00 45.92  ?  230 SER C C     1 
ATOM 3769 O O     . SER B 1 230 ? 108.462 110.873 126.321 1.00 45.92  ?  230 SER C O     1 
ATOM 3770 C CB    . SER B 1 230 ? 107.186 108.390 124.064 1.00 45.92  ?  230 SER C CB    1 
ATOM 3771 O OG    . SER B 1 230 ? 105.837 108.045 124.320 1.00 45.92  ?  230 SER C OG    1 
ATOM 3772 N N     . ALA B 1 231 ? 106.655 109.573 126.668 1.00 46.35  ?  231 ALA C N     1 
ATOM 3773 C CA    . ALA B 1 231 ? 106.595 109.854 128.097 1.00 46.35  ?  231 ALA C CA    1 
ATOM 3774 C C     . ALA B 1 231 ? 107.718 109.126 128.826 1.00 46.35  ?  231 ALA C C     1 
ATOM 3775 O O     . ALA B 1 231 ? 107.808 107.895 128.769 1.00 46.35  ?  231 ALA C O     1 
ATOM 3776 C CB    . ALA B 1 231 ? 105.235 109.447 128.659 1.00 46.35  ?  231 ALA C CB    1 
ATOM 3777 N N     . ASP B 1 232 ? 108.567 109.893 129.514 1.00 48.20  ?  232 ASP C N     1 
ATOM 3778 C CA    . ASP B 1 232 ? 109.617 109.353 130.382 1.00 48.20  ?  232 ASP C CA    1 
ATOM 3779 C C     . ASP B 1 232 ? 110.572 108.429 129.629 1.00 48.20  ?  232 ASP C C     1 
ATOM 3780 O O     . ASP B 1 232 ? 111.002 107.397 130.146 1.00 48.20  ?  232 ASP C O     1 
ATOM 3781 C CB    . ASP B 1 232 ? 109.013 108.635 131.589 1.00 48.20  ?  232 ASP C CB    1 
ATOM 3782 C CG    . ASP B 1 232 ? 109.900 108.710 132.813 1.00 48.20  ?  232 ASP C CG    1 
ATOM 3783 O OD1   . ASP B 1 232 ? 111.122 108.911 132.650 1.00 48.20  ?  232 ASP C OD1   1 
ATOM 3784 O OD2   . ASP B 1 232 ? 109.377 108.569 133.939 1.00 48.20  -1 232 ASP C OD2   1 
ATOM 3785 N N     . VAL B 1 233 ? 110.912 108.801 128.399 1.00 42.51  ?  233 VAL C N     1 
ATOM 3786 C CA    . VAL B 1 233 ? 111.913 108.072 127.623 1.00 42.51  ?  233 VAL C CA    1 
ATOM 3787 C C     . VAL B 1 233 ? 112.868 109.087 127.005 1.00 42.51  ?  233 VAL C C     1 
ATOM 3788 O O     . VAL B 1 233 ? 112.480 110.242 126.783 1.00 42.51  ?  233 VAL C O     1 
ATOM 3789 C CB    . VAL B 1 233 ? 111.260 107.191 126.547 1.00 42.51  ?  233 VAL C CB    1 
ATOM 3790 C CG1   . VAL B 1 233 ? 110.589 105.985 127.182 1.00 42.51  ?  233 VAL C CG1   1 
ATOM 3791 C CG2   . VAL B 1 233 ? 110.270 107.996 125.742 1.00 42.51  ?  233 VAL C CG2   1 
ATOM 3792 N N     . PRO B 1 234 ? 114.113 108.714 126.721 1.00 36.34  ?  234 PRO C N     1 
ATOM 3793 C CA    . PRO B 1 234 ? 115.060 109.685 126.165 1.00 36.34  ?  234 PRO C CA    1 
ATOM 3794 C C     . PRO B 1 234 ? 114.651 110.155 124.779 1.00 36.34  ?  234 PRO C C     1 
ATOM 3795 O O     . PRO B 1 234 ? 114.008 109.434 124.013 1.00 36.34  ?  234 PRO C O     1 
ATOM 3796 C CB    . PRO B 1 234 ? 116.381 108.908 126.117 1.00 36.34  ?  234 PRO C CB    1 
ATOM 3797 C CG    . PRO B 1 234 ? 116.187 107.749 127.031 1.00 36.34  ?  234 PRO C CG    1 
ATOM 3798 C CD    . PRO B 1 234 ? 114.742 107.406 126.955 1.00 36.34  ?  234 PRO C CD    1 
ATOM 3799 N N     . LEU B 1 235 ? 115.033 111.390 124.467 1.00 39.06  ?  235 LEU C N     1 
ATOM 3800 C CA    . LEU B 1 235 ? 114.770 111.967 123.157 1.00 39.06  ?  235 LEU C CA    1 
ATOM 3801 C C     . LEU B 1 235 ? 115.772 111.441 122.139 1.00 39.06  ?  235 LEU C C     1 
ATOM 3802 O O     . LEU B 1 235 ? 116.959 111.288 122.438 1.00 39.06  ?  235 LEU C O     1 
ATOM 3803 C CB    . LEU B 1 235 ? 114.844 113.491 123.228 1.00 39.06  ?  235 LEU C CB    1 
ATOM 3804 C CG    . LEU B 1 235 ? 114.889 114.257 121.908 1.00 39.06  ?  235 LEU C CG    1 
ATOM 3805 C CD1   . LEU B 1 235 ? 113.485 114.587 121.435 1.00 39.06  ?  235 LEU C CD1   1 
ATOM 3806 C CD2   . LEU B 1 235 ? 115.718 115.519 122.053 1.00 39.06  ?  235 LEU C CD2   1 
ATOM 3807 N N     . VAL B 1 236 ? 115.290 111.167 120.929 1.00 39.53  ?  236 VAL C N     1 
ATOM 3808 C CA    . VAL B 1 236 ? 116.112 110.621 119.855 1.00 39.53  ?  236 VAL C CA    1 
ATOM 3809 C C     . VAL B 1 236 ? 116.166 111.641 118.729 1.00 39.53  ?  236 VAL C C     1 
ATOM 3810 O O     . VAL B 1 236 ? 115.130 111.986 118.148 1.00 39.53  ?  236 VAL C O     1 
ATOM 3811 C CB    . VAL B 1 236 ? 115.567 109.280 119.346 1.00 39.53  ?  236 VAL C CB    1 
ATOM 3812 C CG1   . VAL B 1 236 ? 116.175 108.939 118.002 1.00 39.53  ?  236 VAL C CG1   1 
ATOM 3813 C CG2   . VAL B 1 236 ? 115.847 108.186 120.350 1.00 39.53  ?  236 VAL C CG2   1 
ATOM 3814 N N     . VAL B 1 237 ? 117.368 112.112 118.415 1.00 54.26  ?  237 VAL C N     1 
ATOM 3815 C CA    . VAL B 1 237 ? 117.604 113.028 117.306 1.00 54.26  ?  237 VAL C CA    1 
ATOM 3816 C C     . VAL B 1 237 ? 118.398 112.270 116.254 1.00 54.26  ?  237 VAL C C     1 
ATOM 3817 O O     . VAL B 1 237 ? 119.531 111.848 116.511 1.00 54.26  ?  237 VAL C O     1 
ATOM 3818 C CB    . VAL B 1 237 ? 118.353 114.287 117.762 1.00 54.26  ?  237 VAL C CB    1 
ATOM 3819 C CG1   . VAL B 1 237 ? 118.305 115.346 116.689 1.00 54.26  ?  237 VAL C CG1   1 
ATOM 3820 C CG2   . VAL B 1 237 ? 117.765 114.811 119.054 1.00 54.26  ?  237 VAL C CG2   1 
ATOM 3821 N N     . GLU B 1 238 ? 117.814 112.097 115.072 1.00 54.26  ?  238 GLU C N     1 
ATOM 3822 C CA    . GLU B 1 238 ? 118.373 111.223 114.050 1.00 54.26  ?  238 GLU C CA    1 
ATOM 3823 C C     . GLU B 1 238 ? 118.654 112.002 112.775 1.00 54.26  ?  238 GLU C C     1 
ATOM 3824 O O     . GLU B 1 238 ? 117.774 112.698 112.261 1.00 54.26  ?  238 GLU C O     1 
ATOM 3825 C CB    . GLU B 1 238 ? 117.424 110.063 113.754 1.00 54.26  ?  238 GLU C CB    1 
ATOM 3826 C CG    . GLU B 1 238 ? 117.649 109.407 112.409 1.00 54.26  ?  238 GLU C CG    1 
ATOM 3827 C CD    . GLU B 1 238 ? 116.948 108.071 112.294 1.00 54.26  ?  238 GLU C CD    1 
ATOM 3828 O OE1   . GLU B 1 238 ? 116.356 107.624 113.298 1.00 54.26  ?  238 GLU C OE1   1 
ATOM 3829 O OE2   . GLU B 1 238 ? 116.990 107.467 111.203 1.00 54.26  -1 238 GLU C OE2   1 
ATOM 3830 N N     . TYR B 1 239 ? 119.875 111.873 112.265 1.00 54.26  ?  239 TYR C N     1 
ATOM 3831 C CA    . TYR B 1 239 ? 120.265 112.413 110.971 1.00 54.26  ?  239 TYR C CA    1 
ATOM 3832 C C     . TYR B 1 239 ? 120.611 111.261 110.040 1.00 54.26  ?  239 TYR C C     1 
ATOM 3833 O O     . TYR B 1 239 ? 121.265 110.298 110.450 1.00 54.26  ?  239 TYR C O     1 
ATOM 3834 C CB    . TYR B 1 239 ? 121.467 113.352 111.087 1.00 54.26  ?  239 TYR C CB    1 
ATOM 3835 C CG    . TYR B 1 239 ? 121.243 114.561 111.960 1.00 54.26  ?  239 TYR C CG    1 
ATOM 3836 C CD1   . TYR B 1 239 ? 121.362 114.479 113.337 1.00 54.26  ?  239 TYR C CD1   1 
ATOM 3837 C CD2   . TYR B 1 239 ? 120.925 115.789 111.404 1.00 54.26  ?  239 TYR C CD2   1 
ATOM 3838 C CE1   . TYR B 1 239 ? 121.163 115.582 114.135 1.00 54.26  ?  239 TYR C CE1   1 
ATOM 3839 C CE2   . TYR B 1 239 ? 120.724 116.897 112.194 1.00 54.26  ?  239 TYR C CE2   1 
ATOM 3840 C CZ    . TYR B 1 239 ? 120.844 116.789 113.558 1.00 54.26  ?  239 TYR C CZ    1 
ATOM 3841 O OH    . TYR B 1 239 ? 120.644 117.893 114.350 1.00 54.26  ?  239 TYR C OH    1 
ATOM 3842 N N     . LYS B 1 240 ? 120.179 111.361 108.789 1.00 38.18  ?  240 LYS C N     1 
ATOM 3843 C CA    . LYS B 1 240 ? 120.422 110.323 107.796 1.00 38.18  ?  240 LYS C CA    1 
ATOM 3844 C C     . LYS B 1 240 ? 121.635 110.707 106.959 1.00 38.18  ?  240 LYS C C     1 
ATOM 3845 O O     . LYS B 1 240 ? 121.633 111.753 106.303 1.00 38.18  ?  240 LYS C O     1 
ATOM 3846 C CB    . LYS B 1 240 ? 119.197 110.123 106.907 1.00 38.18  ?  240 LYS C CB    1 
ATOM 3847 C CG    . LYS B 1 240 ? 119.108 108.744 106.284 1.00 38.18  ?  240 LYS C CG    1 
ATOM 3848 C CD    . LYS B 1 240 ? 118.755 107.696 107.321 1.00 38.18  ?  240 LYS C CD    1 
ATOM 3849 C CE    . LYS B 1 240 ? 117.263 107.675 107.595 1.00 38.18  ?  240 LYS C CE    1 
ATOM 3850 N NZ    . LYS B 1 240 ? 116.953 107.076 108.920 1.00 38.18  1  240 LYS C NZ    1 
ATOM 3851 N N     . ILE B 1 241 ? 122.660 109.861 106.976 1.00 39.11  ?  241 ILE C N     1 
ATOM 3852 C CA    . ILE B 1 241 ? 123.898 110.134 106.227 1.00 39.11  ?  241 ILE C CA    1 
ATOM 3853 C C     . ILE B 1 241 ? 123.693 109.540 104.840 1.00 39.11  ?  241 ILE C C     1 
ATOM 3854 O O     . ILE B 1 241 ? 124.115 108.424 104.527 1.00 39.11  ?  241 ILE C O     1 
ATOM 3855 C CB    . ILE B 1 241 ? 125.137 109.575 106.931 1.00 39.11  ?  241 ILE C CB    1 
ATOM 3856 C CG1   . ILE B 1 241 ? 125.245 110.133 108.348 1.00 39.11  ?  241 ILE C CG1   1 
ATOM 3857 C CG2   . ILE B 1 241 ? 126.390 109.915 106.149 1.00 39.11  ?  241 ILE C CG2   1 
ATOM 3858 C CD1   . ILE B 1 241 ? 126.504 109.710 109.063 1.00 39.11  ?  241 ILE C CD1   1 
ATOM 3859 N N     . ALA B 1 242 ? 123.032 110.316 103.979 1.00 41.03  ?  242 ALA C N     1 
ATOM 3860 C CA    . ALA B 1 242 ? 122.762 109.920 102.600 1.00 41.03  ?  242 ALA C CA    1 
ATOM 3861 C C     . ALA B 1 242 ? 122.149 108.528 102.530 1.00 41.03  ?  242 ALA C C     1 
ATOM 3862 O O     . ALA B 1 242 ? 121.099 108.270 103.127 1.00 41.03  ?  242 ALA C O     1 
ATOM 3863 C CB    . ALA B 1 242 ? 124.044 109.977 101.767 1.00 41.03  ?  242 ALA C CB    1 
ATOM 3864 N N     . ASP B 1 243 ? 122.802 107.626 101.799 1.00 47.58  ?  243 ASP C N     1 
ATOM 3865 C CA    . ASP B 1 243 ? 122.402 106.228 101.717 1.00 47.58  ?  243 ASP C CA    1 
ATOM 3866 C C     . ASP B 1 243 ? 123.392 105.311 102.425 1.00 47.58  ?  243 ASP C C     1 
ATOM 3867 O O     . ASP B 1 243 ? 123.393 104.100 102.187 1.00 47.58  ?  243 ASP C O     1 
ATOM 3868 C CB    . ASP B 1 243 ? 122.249 105.811 100.256 1.00 47.58  ?  243 ASP C CB    1 
ATOM 3869 C CG    . ASP B 1 243 ? 123.528 105.995 99.466  1.00 47.58  ?  243 ASP C CG    1 
ATOM 3870 O OD1   . ASP B 1 243 ? 124.350 106.848 99.862  1.00 47.58  ?  243 ASP C OD1   1 
ATOM 3871 O OD2   . ASP B 1 243 ? 123.713 105.290 98.453  1.00 47.58  -1 243 ASP C OD2   1 
ATOM 3872 N N     . MET B 1 244 ? 124.238 105.869 103.289 1.00 42.47  ?  244 MET C N     1 
ATOM 3873 C CA    . MET B 1 244 ? 125.321 105.120 103.909 1.00 42.47  ?  244 MET C CA    1 
ATOM 3874 C C     . MET B 1 244 ? 125.051 104.735 105.356 1.00 42.47  ?  244 MET C C     1 
ATOM 3875 O O     . MET B 1 244 ? 125.738 103.852 105.879 1.00 42.47  ?  244 MET C O     1 
ATOM 3876 C CB    . MET B 1 244 ? 126.621 105.928 103.833 1.00 42.47  ?  244 MET C CB    1 
ATOM 3877 C CG    . MET B 1 244 ? 127.813 105.123 103.374 1.00 42.47  ?  244 MET C CG    1 
ATOM 3878 S SD    . MET B 1 244 ? 129.288 106.114 103.096 1.00 42.47  ?  244 MET C SD    1 
ATOM 3879 C CE    . MET B 1 244 ? 129.306 107.114 104.574 1.00 42.47  ?  244 MET C CE    1 
ATOM 3880 N N     . GLY B 1 245 ? 124.082 105.364 106.011 1.00 42.15  ?  245 GLY C N     1 
ATOM 3881 C CA    . GLY B 1 245 ? 123.812 105.039 107.403 1.00 42.15  ?  245 GLY C CA    1 
ATOM 3882 C C     . GLY B 1 245 ? 122.999 106.121 108.075 1.00 42.15  ?  245 GLY C C     1 
ATOM 3883 O O     . GLY B 1 245 ? 122.223 106.830 107.427 1.00 42.15  ?  245 GLY C O     1 
ATOM 3884 N N     . HIS B 1 246 ? 123.188 106.238 109.387 1.00 37.34  ?  246 HIS C N     1 
ATOM 3885 C CA    . HIS B 1 246 ? 122.451 107.212 110.177 1.00 37.34  ?  246 HIS C CA    1 
ATOM 3886 C C     . HIS B 1 246 ? 123.268 107.588 111.401 1.00 37.34  ?  246 HIS C C     1 
ATOM 3887 O O     . HIS B 1 246 ? 124.208 106.890 111.785 1.00 37.34  ?  246 HIS C O     1 
ATOM 3888 C CB    . HIS B 1 246 ? 121.082 106.675 110.597 1.00 37.34  ?  246 HIS C CB    1 
ATOM 3889 C CG    . HIS B 1 246 ? 121.152 105.461 111.466 1.00 37.34  ?  246 HIS C CG    1 
ATOM 3890 N ND1   . HIS B 1 246 ? 120.906 104.192 110.991 1.00 37.34  ?  246 HIS C ND1   1 
ATOM 3891 C CD2   . HIS B 1 246 ? 121.439 105.321 112.782 1.00 37.34  ?  246 HIS C CD2   1 
ATOM 3892 C CE1   . HIS B 1 246 ? 121.039 103.322 111.976 1.00 37.34  ?  246 HIS C CE1   1 
ATOM 3893 N NE2   . HIS B 1 246 ? 121.362 103.982 113.073 1.00 37.34  ?  246 HIS C NE2   1 
ATOM 3894 N N     . LEU B 1 247 ? 122.891 108.707 112.014 1.00 54.26  ?  247 LEU C N     1 
ATOM 3895 C CA    . LEU B 1 247 ? 123.559 109.230 113.201 1.00 54.26  ?  247 LEU C CA    1 
ATOM 3896 C C     . LEU B 1 247 ? 122.490 109.612 114.214 1.00 54.26  ?  247 LEU C C     1 
ATOM 3897 O O     . LEU B 1 247 ? 121.716 110.545 113.979 1.00 54.26  ?  247 LEU C O     1 
ATOM 3898 C CB    . LEU B 1 247 ? 124.434 110.431 112.849 1.00 54.26  ?  247 LEU C CB    1 
ATOM 3899 C CG    . LEU B 1 247 ? 125.288 111.022 113.967 1.00 54.26  ?  247 LEU C CG    1 
ATOM 3900 C CD1   . LEU B 1 247 ? 126.429 110.090 114.312 1.00 54.26  ?  247 LEU C CD1   1 
ATOM 3901 C CD2   . LEU B 1 247 ? 125.816 112.380 113.559 1.00 54.26  ?  247 LEU C CD2   1 
ATOM 3902 N N     . LYS B 1 248 ? 122.445 108.901 115.335 1.00 54.26  ?  248 LYS C N     1 
ATOM 3903 C CA    . LYS B 1 248 ? 121.430 109.110 116.357 1.00 54.26  ?  248 LYS C CA    1 
ATOM 3904 C C     . LYS B 1 248 ? 122.060 109.657 117.628 1.00 54.26  ?  248 LYS C C     1 
ATOM 3905 O O     . LYS B 1 248 ? 123.153 109.239 118.021 1.00 54.26  ?  248 LYS C O     1 
ATOM 3906 C CB    . LYS B 1 248 ? 120.697 107.809 116.679 1.00 54.26  ?  248 LYS C CB    1 
ATOM 3907 C CG    . LYS B 1 248 ? 119.901 107.239 115.531 1.00 54.26  ?  248 LYS C CG    1 
ATOM 3908 C CD    . LYS B 1 248 ? 119.170 105.984 115.963 1.00 54.26  ?  248 LYS C CD    1 
ATOM 3909 C CE    . LYS B 1 248 ? 118.297 105.443 114.848 1.00 54.26  ?  248 LYS C CE    1 
ATOM 3910 N NZ    . LYS B 1 248 ? 117.525 104.249 115.285 1.00 54.26  1  248 LYS C NZ    1 
ATOM 3911 N N     . TYR B 1 249 ? 121.363 110.588 118.269 1.00 54.26  ?  249 TYR C N     1 
ATOM 3912 C CA    . TYR B 1 249 ? 121.746 111.104 119.573 1.00 54.26  ?  249 TYR C CA    1 
ATOM 3913 C C     . TYR B 1 249 ? 120.658 110.773 120.584 1.00 54.26  ?  249 TYR C C     1 
ATOM 3914 O O     . TYR B 1 249 ? 119.494 110.581 120.225 1.00 54.26  ?  249 TYR C O     1 
ATOM 3915 C CB    . TYR B 1 249 ? 121.965 112.616 119.545 1.00 54.26  ?  249 TYR C CB    1 
ATOM 3916 C CG    . TYR B 1 249 ? 123.065 113.086 118.626 1.00 54.26  ?  249 TYR C CG    1 
ATOM 3917 C CD1   . TYR B 1 249 ? 122.844 113.234 117.267 1.00 54.26  ?  249 TYR C CD1   1 
ATOM 3918 C CD2   . TYR B 1 249 ? 124.317 113.402 119.122 1.00 54.26  ?  249 TYR C CD2   1 
ATOM 3919 C CE1   . TYR B 1 249 ? 123.844 113.674 116.429 1.00 54.26  ?  249 TYR C CE1   1 
ATOM 3920 C CE2   . TYR B 1 249 ? 125.322 113.843 118.292 1.00 54.26  ?  249 TYR C CE2   1 
ATOM 3921 C CZ    . TYR B 1 249 ? 125.080 113.976 116.948 1.00 54.26  ?  249 TYR C CZ    1 
ATOM 3922 O OH    . TYR B 1 249 ? 126.082 114.414 116.118 1.00 54.26  ?  249 TYR C OH    1 
ATOM 3923 N N     . TYR B 1 250 ? 121.044 110.711 121.853 1.00 54.26  ?  250 TYR C N     1 
ATOM 3924 C CA    . TYR B 1 250 ? 120.109 110.455 122.936 1.00 54.26  ?  250 TYR C CA    1 
ATOM 3925 C C     . TYR B 1 250 ? 120.306 111.495 124.025 1.00 54.26  ?  250 TYR C C     1 
ATOM 3926 O O     . TYR B 1 250 ? 121.428 111.952 124.261 1.00 54.26  ?  250 TYR C O     1 
ATOM 3927 C CB    . TYR B 1 250 ? 120.296 109.054 123.517 1.00 54.26  ?  250 TYR C CB    1 
ATOM 3928 C CG    . TYR B 1 250 ? 119.902 107.936 122.583 1.00 54.26  ?  250 TYR C CG    1 
ATOM 3929 C CD1   . TYR B 1 250 ? 120.749 107.521 121.570 1.00 54.26  ?  250 TYR C CD1   1 
ATOM 3930 C CD2   . TYR B 1 250 ? 118.688 107.286 122.724 1.00 54.26  ?  250 TYR C CD2   1 
ATOM 3931 C CE1   . TYR B 1 250 ? 120.395 106.497 120.720 1.00 54.26  ?  250 TYR C CE1   1 
ATOM 3932 C CE2   . TYR B 1 250 ? 118.326 106.261 121.880 1.00 54.26  ?  250 TYR C CE2   1 
ATOM 3933 C CZ    . TYR B 1 250 ? 119.184 105.872 120.879 1.00 54.26  ?  250 TYR C CZ    1 
ATOM 3934 O OH    . TYR B 1 250 ? 118.828 104.850 120.033 1.00 54.26  ?  250 TYR C OH    1 
ATOM 3935 N N     . LEU B 1 251 ? 119.214 111.869 124.687 1.00 35.29  ?  251 LEU C N     1 
ATOM 3936 C CA    . LEU B 1 251 ? 119.259 112.853 125.757 1.00 35.29  ?  251 LEU C CA    1 
ATOM 3937 C C     . LEU B 1 251 ? 118.232 112.490 126.816 1.00 35.29  ?  251 LEU C C     1 
ATOM 3938 O O     . LEU B 1 251 ? 117.129 112.045 126.492 1.00 35.29  ?  251 LEU C O     1 
ATOM 3939 C CB    . LEU B 1 251 ? 118.995 114.265 125.226 1.00 35.29  ?  251 LEU C CB    1 
ATOM 3940 C CG    . LEU B 1 251 ? 119.214 115.406 126.216 1.00 35.29  ?  251 LEU C CG    1 
ATOM 3941 C CD1   . LEU B 1 251 ? 120.651 115.425 126.683 1.00 35.29  ?  251 LEU C CD1   1 
ATOM 3942 C CD2   . LEU B 1 251 ? 118.848 116.729 125.583 1.00 35.29  ?  251 LEU C CD2   1 
ATOM 3943 N N     . ALA B 1 252 ? 118.599 112.683 128.082 1.00 36.08  ?  252 ALA C N     1 
ATOM 3944 C CA    . ALA B 1 252 ? 117.716 112.347 129.191 1.00 36.08  ?  252 ALA C CA    1 
ATOM 3945 C C     . ALA B 1 252 ? 116.894 113.566 129.583 1.00 36.08  ?  252 ALA C C     1 
ATOM 3946 O O     . ALA B 1 252 ? 117.475 114.598 129.943 1.00 36.08  ?  252 ALA C O     1 
ATOM 3947 C CB    . ALA B 1 252 ? 118.516 111.857 130.384 1.00 36.08  ?  252 ALA C CB    1 
ATOM 3948 N N     . PRO B 1 253 ? 115.566 113.499 129.530 1.00 37.41  ?  253 PRO C N     1 
ATOM 3949 C CA    . PRO B 1 253 ? 114.755 114.671 129.875 1.00 37.41  ?  253 PRO C CA    1 
ATOM 3950 C C     . PRO B 1 253 ? 114.970 115.093 131.319 1.00 37.41  ?  253 PRO C C     1 
ATOM 3951 O O     . PRO B 1 253 ? 115.156 114.261 132.209 1.00 37.41  ?  253 PRO C O     1 
ATOM 3952 C CB    . PRO B 1 253 ? 113.319 114.191 129.638 1.00 37.41  ?  253 PRO C CB    1 
ATOM 3953 C CG    . PRO B 1 253 ? 113.392 112.712 129.746 1.00 37.41  ?  253 PRO C CG    1 
ATOM 3954 C CD    . PRO B 1 253 ? 114.735 112.328 129.208 1.00 37.41  ?  253 PRO C CD    1 
ATOM 3955 N N     . LYS B 1 254 ? 114.946 116.402 131.544 1.00 52.77  ?  254 LYS C N     1 
ATOM 3956 C CA    . LYS B 1 254 ? 115.089 116.933 132.889 1.00 52.77  ?  254 LYS C CA    1 
ATOM 3957 C C     . LYS B 1 254 ? 113.881 116.567 133.742 1.00 52.77  ?  254 LYS C C     1 
ATOM 3958 O O     . LYS B 1 254 ? 112.754 116.462 133.253 1.00 52.77  ?  254 LYS C O     1 
ATOM 3959 C CB    . LYS B 1 254 ? 115.253 118.451 132.852 1.00 52.77  ?  254 LYS C CB    1 
ATOM 3960 C CG    . LYS B 1 254 ? 116.689 118.931 132.926 1.00 52.77  ?  254 LYS C CG    1 
ATOM 3961 C CD    . LYS B 1 254 ? 116.743 120.442 133.075 1.00 52.77  ?  254 LYS C CD    1 
ATOM 3962 C CE    . LYS B 1 254 ? 118.156 120.925 133.341 1.00 52.77  ?  254 LYS C CE    1 
ATOM 3963 N NZ    . LYS B 1 254 ? 118.209 122.404 133.497 1.00 52.77  1  254 LYS C NZ    1 
ATOM 3964 N N     . ILE B 1 255 ? 114.129 116.367 135.030 1.00 90.04  ?  255 ILE C N     1 
ATOM 3965 C CA    . ILE B 1 255 ? 113.058 116.094 135.979 1.00 90.04  ?  255 ILE C CA    1 
ATOM 3966 C C     . ILE B 1 255 ? 112.385 117.405 136.355 1.00 90.04  ?  255 ILE C C     1 
ATOM 3967 O O     . ILE B 1 255 ? 113.037 118.452 136.450 1.00 90.04  ?  255 ILE C O     1 
ATOM 3968 C CB    . ILE B 1 255 ? 113.604 115.366 137.220 1.00 90.04  ?  255 ILE C CB    1 
ATOM 3969 C CG1   . ILE B 1 255 ? 114.587 114.271 136.805 1.00 90.04  ?  255 ILE C CG1   1 
ATOM 3970 C CG2   . ILE B 1 255 ? 112.468 114.773 138.036 1.00 90.04  ?  255 ILE C CG2   1 
ATOM 3971 C CD1   . ILE B 1 255 ? 115.272 113.598 137.972 1.00 90.04  ?  255 ILE C CD1   1 
ATOM 3972 N N     . GLU B 1 256 ? 111.067 117.353 136.563 1.00 120.94 ?  256 GLU C N     1 
ATOM 3973 C CA    . GLU B 1 256 ? 110.322 118.561 136.901 1.00 120.94 ?  256 GLU C CA    1 
ATOM 3974 C C     . GLU B 1 256 ? 110.783 119.141 138.232 1.00 120.94 ?  256 GLU C C     1 
ATOM 3975 O O     . GLU B 1 256 ? 110.831 120.365 138.401 1.00 120.94 ?  256 GLU C O     1 
ATOM 3976 C CB    . GLU B 1 256 ? 108.824 118.262 136.934 1.00 120.94 ?  256 GLU C CB    1 
ATOM 3977 C CG    . GLU B 1 256 ? 108.171 118.224 135.561 1.00 120.94 ?  256 GLU C CG    1 
ATOM 3978 C CD    . GLU B 1 256 ? 106.670 118.021 135.633 1.00 120.94 ?  256 GLU C CD    1 
ATOM 3979 O OE1   . GLU B 1 256 ? 106.131 117.961 136.758 1.00 120.94 ?  256 GLU C OE1   1 
ATOM 3980 O OE2   . GLU B 1 256 ? 106.031 117.923 134.565 1.00 120.94 -1 256 GLU C OE2   1 
ATOM 3981 N N     . ASP B 1 257 ? 111.125 118.278 139.192 1.00 133.12 ?  257 ASP C N     1 
ATOM 3982 C CA    . ASP B 1 257 ? 111.576 118.750 140.495 1.00 133.12 ?  257 ASP C CA    1 
ATOM 3983 C C     . ASP B 1 257 ? 112.909 119.482 140.422 1.00 133.12 ?  257 ASP C C     1 
ATOM 3984 O O     . ASP B 1 257 ? 113.239 120.235 141.345 1.00 133.12 ?  257 ASP C O     1 
ATOM 3985 C CB    . ASP B 1 257 ? 111.679 117.578 141.472 1.00 133.12 ?  257 ASP C CB    1 
ATOM 3986 C CG    . ASP B 1 257 ? 110.361 117.271 142.153 1.00 133.12 ?  257 ASP C CG    1 
ATOM 3987 O OD1   . ASP B 1 257 ? 109.441 118.112 142.077 1.00 133.12 ?  257 ASP C OD1   1 
ATOM 3988 O OD2   . ASP B 1 257 ? 110.244 116.188 142.764 1.00 133.12 -1 257 ASP C OD2   1 
ATOM 3989 N N     . GLU B 1 258 ? 113.683 119.278 139.353 1.00 109.16 ?  258 GLU C N     1 
ATOM 3990 C CA    . GLU B 1 258 ? 114.940 120.004 139.201 1.00 109.16 ?  258 GLU C CA    1 
ATOM 3991 C C     . GLU B 1 258 ? 114.705 121.497 139.025 1.00 109.16 ?  258 GLU C C     1 
ATOM 3992 O O     . GLU B 1 258 ? 115.515 122.310 139.483 1.00 109.16 ?  258 GLU C O     1 
ATOM 3993 C CB    . GLU B 1 258 ? 115.729 119.450 138.016 1.00 109.16 ?  258 GLU C CB    1 
ATOM 3994 C CG    . GLU B 1 258 ? 116.357 118.094 138.270 1.00 109.16 ?  258 GLU C CG    1 
ATOM 3995 C CD    . GLU B 1 258 ? 116.490 117.274 137.005 1.00 109.16 ?  258 GLU C CD    1 
ATOM 3996 O OE1   . GLU B 1 258 ? 115.915 117.677 135.973 1.00 109.16 ?  258 GLU C OE1   1 
ATOM 3997 O OE2   . GLU B 1 258 ? 117.165 116.225 137.042 1.00 109.16 -1 258 GLU C OE2   1 
ATOM 3998 N N     . GLU B 1 259 ? 113.609 121.874 138.366 1.00 124.05 ?  259 GLU C N     1 
ATOM 3999 C CA    . GLU B 1 259 ? 113.270 123.277 138.171 1.00 124.05 ?  259 GLU C CA    1 
ATOM 4000 C C     . GLU B 1 259 ? 112.827 123.963 139.456 1.00 124.05 ?  259 GLU C C     1 
ATOM 4001 O O     . GLU B 1 259 ? 112.818 125.198 139.506 1.00 124.05 ?  259 GLU C O     1 
ATOM 4002 C CB    . GLU B 1 259 ? 112.166 123.403 137.118 1.00 124.05 ?  259 GLU C CB    1 
ATOM 4003 C CG    . GLU B 1 259 ? 112.624 123.114 135.699 1.00 124.05 ?  259 GLU C CG    1 
ATOM 4004 C CD    . GLU B 1 259 ? 111.477 122.727 134.786 1.00 124.05 ?  259 GLU C CD    1 
ATOM 4005 O OE1   . GLU B 1 259 ? 110.338 122.600 135.282 1.00 124.05 ?  259 GLU C OE1   1 
ATOM 4006 O OE2   . GLU B 1 259 ? 111.713 122.550 133.572 1.00 124.05 -1 259 GLU C OE2   1 
ATOM 4007 N N     . GLY B 1 260 ? 112.457 123.200 140.486 1.00 129.10 ?  260 GLY C N     1 
ATOM 4008 C CA    . GLY B 1 260 ? 112.042 123.813 141.737 1.00 129.10 ?  260 GLY C CA    1 
ATOM 4009 C C     . GLY B 1 260 ? 113.174 124.535 142.443 1.00 129.10 ?  260 GLY C C     1 
ATOM 4010 O O     . GLY B 1 260 ? 112.967 125.593 143.044 1.00 129.10 ?  260 GLY C O     1 
ATOM 4011 N N     . SER B 1 261 ? 114.379 123.978 142.382 1.00 129.44 ?  261 SER C N     1 
ATOM 4012 C CA    . SER B 1 261 ? 115.538 124.586 143.026 1.00 129.44 ?  261 SER C CA    1 
ATOM 4013 C C     . SER B 1 261 ? 115.967 125.856 142.299 1.00 129.44 ?  261 SER C C     1 
ATOM 4014 O O     . SER B 1 261 ? 115.655 126.046 141.123 1.00 129.44 ?  261 SER C O     1 
ATOM 4015 C CB    . SER B 1 261 ? 116.701 123.594 143.083 1.00 129.44 ?  261 SER C CB    1 
ATOM 4016 O OG    . SER B 1 261 ? 116.303 122.376 143.688 1.00 129.44 ?  261 SER C OG    1 
ATOM 4017 N N     . MET C 1 1   ? 167.484 164.392 98.617  1.00 85.49  ?  1   MET D N     1 
ATOM 4018 C CA    . MET C 1 1   ? 166.182 163.889 99.040  1.00 85.49  ?  1   MET D CA    1 
ATOM 4019 C C     . MET C 1 1   ? 165.795 162.640 98.255  1.00 85.49  ?  1   MET D C     1 
ATOM 4020 O O     . MET C 1 1   ? 166.231 162.447 97.121  1.00 85.49  ?  1   MET D O     1 
ATOM 4021 C CB    . MET C 1 1   ? 165.122 164.992 98.905  1.00 85.49  ?  1   MET D CB    1 
ATOM 4022 C CG    . MET C 1 1   ? 164.892 165.540 97.495  1.00 85.49  ?  1   MET D CG    1 
ATOM 4023 S SD    . MET C 1 1   ? 163.951 164.497 96.363  1.00 85.49  ?  1   MET D SD    1 
ATOM 4024 C CE    . MET C 1 1   ? 162.279 165.017 96.741  1.00 85.49  ?  1   MET D CE    1 
ATOM 4025 N N     . PHE C 1 2   ? 164.989 161.786 98.879  1.00 64.52  ?  2   PHE D N     1 
ATOM 4026 C CA    . PHE C 1 2   ? 164.564 160.522 98.295  1.00 64.52  ?  2   PHE D CA    1 
ATOM 4027 C C     . PHE C 1 2   ? 163.059 160.554 98.073  1.00 64.52  ?  2   PHE D C     1 
ATOM 4028 O O     . PHE C 1 2   ? 162.301 160.888 98.989  1.00 64.52  ?  2   PHE D O     1 
ATOM 4029 C CB    . PHE C 1 2   ? 164.950 159.349 99.200  1.00 64.52  ?  2   PHE D CB    1 
ATOM 4030 C CG    . PHE C 1 2   ? 164.171 158.093 98.939  1.00 64.52  ?  2   PHE D CG    1 
ATOM 4031 C CD1   . PHE C 1 2   ? 164.192 157.493 97.693  1.00 64.52  ?  2   PHE D CD1   1 
ATOM 4032 C CD2   . PHE C 1 2   ? 163.427 157.504 99.945  1.00 64.52  ?  2   PHE D CD2   1 
ATOM 4033 C CE1   . PHE C 1 2   ? 163.479 156.336 97.456  1.00 64.52  ?  2   PHE D CE1   1 
ATOM 4034 C CE2   . PHE C 1 2   ? 162.714 156.347 99.713  1.00 64.52  ?  2   PHE D CE2   1 
ATOM 4035 C CZ    . PHE C 1 2   ? 162.739 155.763 98.468  1.00 64.52  ?  2   PHE D CZ    1 
ATOM 4036 N N     . GLU C 1 3   ? 162.633 160.208 96.860  1.00 64.22  ?  3   GLU D N     1 
ATOM 4037 C CA    . GLU C 1 3   ? 161.217 160.179 96.513  1.00 64.22  ?  3   GLU D CA    1 
ATOM 4038 C C     . GLU C 1 3   ? 160.952 158.970 95.633  1.00 64.22  ?  3   GLU D C     1 
ATOM 4039 O O     . GLU C 1 3   ? 161.585 158.814 94.585  1.00 64.22  ?  3   GLU D O     1 
ATOM 4040 C CB    . GLU C 1 3   ? 160.793 161.462 95.796  1.00 64.22  ?  3   GLU D CB    1 
ATOM 4041 C CG    . GLU C 1 3   ? 159.443 161.357 95.110  1.00 64.22  ?  3   GLU D CG    1 
ATOM 4042 C CD    . GLU C 1 3   ? 159.152 162.538 94.208  1.00 64.22  ?  3   GLU D CD    1 
ATOM 4043 O OE1   . GLU C 1 3   ? 160.072 163.348 93.971  1.00 64.22  ?  3   GLU D OE1   1 
ATOM 4044 O OE2   . GLU C 1 3   ? 158.003 162.657 93.735  1.00 64.22  -1 3   GLU D OE2   1 
ATOM 4045 N N     . ALA C 1 4   ? 160.016 158.123 96.054  1.00 51.51  ?  4   ALA D N     1 
ATOM 4046 C CA    . ALA C 1 4   ? 159.625 156.940 95.299  1.00 51.51  ?  4   ALA D CA    1 
ATOM 4047 C C     . ALA C 1 4   ? 158.117 156.956 95.121  1.00 51.51  ?  4   ALA D C     1 
ATOM 4048 O O     . ALA C 1 4   ? 157.376 157.013 96.107  1.00 51.51  ?  4   ALA D O     1 
ATOM 4049 C CB    . ALA C 1 4   ? 160.070 155.659 96.007  1.00 51.51  ?  4   ALA D CB    1 
ATOM 4050 N N     . ARG C 1 5   ? 157.665 156.903 93.872  1.00 51.10  ?  5   ARG D N     1 
ATOM 4051 C CA    . ARG C 1 5   ? 156.244 156.897 93.542  1.00 51.10  ?  5   ARG D CA    1 
ATOM 4052 C C     . ARG C 1 5   ? 155.885 155.511 93.025  1.00 51.10  ?  5   ARG D C     1 
ATOM 4053 O O     . ARG C 1 5   ? 156.280 155.133 91.918  1.00 51.10  ?  5   ARG D O     1 
ATOM 4054 C CB    . ARG C 1 5   ? 155.918 157.975 92.512  1.00 51.10  ?  5   ARG D CB    1 
ATOM 4055 C CG    . ARG C 1 5   ? 154.527 157.864 91.916  1.00 51.10  ?  5   ARG D CG    1 
ATOM 4056 C CD    . ARG C 1 5   ? 154.166 159.115 91.134  1.00 51.10  ?  5   ARG D CD    1 
ATOM 4057 N NE    . ARG C 1 5   ? 153.093 158.870 90.179  1.00 51.10  ?  5   ARG D NE    1 
ATOM 4058 C CZ    . ARG C 1 5   ? 151.805 158.842 90.489  1.00 51.10  ?  5   ARG D CZ    1 
ATOM 4059 N NH1   . ARG C 1 5   ? 151.388 159.049 91.727  1.00 51.10  1  5   ARG D NH1   1 
ATOM 4060 N NH2   . ARG C 1 5   ? 150.912 158.601 89.534  1.00 51.10  ?  5   ARG D NH2   1 
ATOM 4061 N N     . LEU C 1 6   ? 155.135 154.759 93.824  1.00 46.91  ?  6   LEU D N     1 
ATOM 4062 C CA    . LEU C 1 6   ? 154.771 153.385 93.508  1.00 46.91  ?  6   LEU D CA    1 
ATOM 4063 C C     . LEU C 1 6   ? 153.290 153.331 93.164  1.00 46.91  ?  6   LEU D C     1 
ATOM 4064 O O     . LEU C 1 6   ? 152.447 153.726 93.975  1.00 46.91  ?  6   LEU D O     1 
ATOM 4065 C CB    . LEU C 1 6   ? 155.086 152.459 94.681  1.00 46.91  ?  6   LEU D CB    1 
ATOM 4066 C CG    . LEU C 1 6   ? 154.904 150.960 94.452  1.00 46.91  ?  6   LEU D CG    1 
ATOM 4067 C CD1   . LEU C 1 6   ? 155.413 150.559 93.079  1.00 46.91  ?  6   LEU D CD1   1 
ATOM 4068 C CD2   . LEU C 1 6   ? 155.615 150.175 95.539  1.00 46.91  ?  6   LEU D CD2   1 
ATOM 4069 N N     . VAL C 1 7   ? 152.978 152.843 91.963  1.00 48.50  ?  7   VAL D N     1 
ATOM 4070 C CA    . VAL C 1 7   ? 151.584 152.743 91.544  1.00 48.50  ?  7   VAL D CA    1 
ATOM 4071 C C     . VAL C 1 7   ? 150.865 151.648 92.322  1.00 48.50  ?  7   VAL D C     1 
ATOM 4072 O O     . VAL C 1 7   ? 149.712 151.816 92.736  1.00 48.50  ?  7   VAL D O     1 
ATOM 4073 C CB    . VAL C 1 7   ? 151.499 152.508 90.026  1.00 48.50  ?  7   VAL D CB    1 
ATOM 4074 C CG1   . VAL C 1 7   ? 150.050 152.416 89.585  1.00 48.50  ?  7   VAL D CG1   1 
ATOM 4075 C CG2   . VAL C 1 7   ? 152.215 153.617 89.283  1.00 48.50  ?  7   VAL D CG2   1 
ATOM 4076 N N     . GLN C 1 8   ? 151.528 150.515 92.533  1.00 48.73  ?  8   GLN D N     1 
ATOM 4077 C CA    . GLN C 1 8   ? 150.921 149.355 93.181  1.00 48.73  ?  8   GLN D CA    1 
ATOM 4078 C C     . GLN C 1 8   ? 151.294 149.368 94.659  1.00 48.73  ?  8   GLN D C     1 
ATOM 4079 O O     . GLN C 1 8   ? 152.376 148.916 95.042  1.00 48.73  ?  8   GLN D O     1 
ATOM 4080 C CB    . GLN C 1 8   ? 151.374 148.065 92.504  1.00 48.73  ?  8   GLN D CB    1 
ATOM 4081 C CG    . GLN C 1 8   ? 150.547 147.609 91.296  1.00 48.73  ?  8   GLN D CG    1 
ATOM 4082 C CD    . GLN C 1 8   ? 149.064 147.944 91.391  1.00 48.73  ?  8   GLN D CD    1 
ATOM 4083 O OE1   . GLN C 1 8   ? 148.654 149.097 91.243  1.00 48.73  ?  8   GLN D OE1   1 
ATOM 4084 N NE2   . GLN C 1 8   ? 148.250 146.925 91.642  1.00 48.73  ?  8   GLN D NE2   1 
ATOM 4085 N N     . GLY C 1 9   ? 150.392 149.888 95.493  1.00 43.11  ?  9   GLY D N     1 
ATOM 4086 C CA    . GLY C 1 9   ? 150.609 149.848 96.928  1.00 43.11  ?  9   GLY D CA    1 
ATOM 4087 C C     . GLY C 1 9   ? 150.389 148.489 97.551  1.00 43.11  ?  9   GLY D C     1 
ATOM 4088 O O     . GLY C 1 9   ? 150.893 148.232 98.651  1.00 43.11  ?  9   GLY D O     1 
ATOM 4089 N N     . SER C 1 10  ? 149.647 147.613 96.870  1.00 43.54  ?  10  SER D N     1 
ATOM 4090 C CA    . SER C 1 10  ? 149.408 146.278 97.403  1.00 43.54  ?  10  SER D CA    1 
ATOM 4091 C C     . SER C 1 10  ? 150.704 145.495 97.545  1.00 43.54  ?  10  SER D C     1 
ATOM 4092 O O     . SER C 1 10  ? 150.831 144.670 98.456  1.00 43.54  ?  10  SER D O     1 
ATOM 4093 C CB    . SER C 1 10  ? 148.424 145.525 96.508  1.00 43.54  ?  10  SER D CB    1 
ATOM 4094 O OG    . SER C 1 10  ? 148.926 145.407 95.190  1.00 43.54  ?  10  SER D OG    1 
ATOM 4095 N N     . ILE C 1 11  ? 151.679 145.743 96.669  1.00 40.23  ?  11  ILE D N     1 
ATOM 4096 C CA    . ILE C 1 11  ? 152.966 145.063 96.778  1.00 40.23  ?  11  ILE D CA    1 
ATOM 4097 C C     . ILE C 1 11  ? 153.646 145.428 98.091  1.00 40.23  ?  11  ILE D C     1 
ATOM 4098 O O     . ILE C 1 11  ? 154.133 144.558 98.824  1.00 40.23  ?  11  ILE D O     1 
ATOM 4099 C CB    . ILE C 1 11  ? 153.856 145.406 95.571  1.00 40.23  ?  11  ILE D CB    1 
ATOM 4100 C CG1   . ILE C 1 11  ? 153.336 144.715 94.312  1.00 40.23  ?  11  ILE D CG1   1 
ATOM 4101 C CG2   . ILE C 1 11  ? 155.290 145.003 95.843  1.00 40.23  ?  11  ILE D CG2   1 
ATOM 4102 C CD1   . ILE C 1 11  ? 154.013 145.177 93.045  1.00 40.23  ?  11  ILE D CD1   1 
ATOM 4103 N N     . LEU C 1 12  ? 153.681 146.723 98.411  1.00 37.74  ?  12  LEU D N     1 
ATOM 4104 C CA    . LEU C 1 12  ? 154.282 147.156 99.667  1.00 37.74  ?  12  LEU D CA    1 
ATOM 4105 C C     . LEU C 1 12  ? 153.497 146.632 100.860 1.00 37.74  ?  12  LEU D C     1 
ATOM 4106 O O     . LEU C 1 12  ? 154.085 146.237 101.874 1.00 37.74  ?  12  LEU D O     1 
ATOM 4107 C CB    . LEU C 1 12  ? 154.373 148.678 99.708  1.00 37.74  ?  12  LEU D CB    1 
ATOM 4108 C CG    . LEU C 1 12  ? 155.745 149.249 99.358  1.00 37.74  ?  12  LEU D CG    1 
ATOM 4109 C CD1   . LEU C 1 12  ? 155.683 150.758 99.246  1.00 37.74  ?  12  LEU D CD1   1 
ATOM 4110 C CD2   . LEU C 1 12  ? 156.762 148.834 100.401 1.00 37.74  ?  12  LEU D CD2   1 
ATOM 4111 N N     . LYS C 1 13  ? 152.166 146.622 100.759 1.00 41.73  ?  13  LYS D N     1 
ATOM 4112 C CA    . LYS C 1 13  ? 151.351 146.083 101.842 1.00 41.73  ?  13  LYS D CA    1 
ATOM 4113 C C     . LYS C 1 13  ? 151.696 144.624 102.110 1.00 41.73  ?  13  LYS D C     1 
ATOM 4114 O O     . LYS C 1 13  ? 151.900 144.221 103.261 1.00 41.73  ?  13  LYS D O     1 
ATOM 4115 C CB    . LYS C 1 13  ? 149.868 146.230 101.502 1.00 41.73  ?  13  LYS D CB    1 
ATOM 4116 C CG    . LYS C 1 13  ? 149.333 147.642 101.639 1.00 41.73  ?  13  LYS D CG    1 
ATOM 4117 C CD    . LYS C 1 13  ? 147.882 147.721 101.199 1.00 41.73  ?  13  LYS D CD    1 
ATOM 4118 C CE    . LYS C 1 13  ? 147.001 146.808 102.034 1.00 41.73  ?  13  LYS D CE    1 
ATOM 4119 N NZ    . LYS C 1 13  ? 146.694 147.400 103.364 1.00 41.73  1  13  LYS D NZ    1 
ATOM 4120 N N     . LYS C 1 14  ? 151.781 143.819 101.048 1.00 40.50  ?  14  LYS D N     1 
ATOM 4121 C CA    . LYS C 1 14  ? 152.095 142.403 101.207 1.00 40.50  ?  14  LYS D CA    1 
ATOM 4122 C C     . LYS C 1 14  ? 153.505 142.202 101.745 1.00 40.50  ?  14  LYS D C     1 
ATOM 4123 O O     . LYS C 1 14  ? 153.731 141.333 102.596 1.00 40.50  ?  14  LYS D O     1 
ATOM 4124 C CB    . LYS C 1 14  ? 151.917 141.677 99.876  1.00 40.50  ?  14  LYS D CB    1 
ATOM 4125 C CG    . LYS C 1 14  ? 150.478 141.616 99.400  1.00 40.50  ?  14  LYS D CG    1 
ATOM 4126 C CD    . LYS C 1 14  ? 150.403 141.546 97.885  1.00 40.50  ?  14  LYS D CD    1 
ATOM 4127 C CE    . LYS C 1 14  ? 148.981 141.761 97.397  1.00 40.50  ?  14  LYS D CE    1 
ATOM 4128 N NZ    . LYS C 1 14  ? 148.908 141.796 95.911  1.00 40.50  1  14  LYS D NZ    1 
ATOM 4129 N N     . VAL C 1 15  ? 154.468 142.991 101.264 1.00 37.47  ?  15  VAL D N     1 
ATOM 4130 C CA    . VAL C 1 15  ? 155.843 142.855 101.739 1.00 37.47  ?  15  VAL D CA    1 
ATOM 4131 C C     . VAL C 1 15  ? 155.920 143.158 103.230 1.00 37.47  ?  15  VAL D C     1 
ATOM 4132 O O     . VAL C 1 15  ? 156.532 142.412 104.006 1.00 37.47  ?  15  VAL D O     1 
ATOM 4133 C CB    . VAL C 1 15  ? 156.782 143.766 100.930 1.00 37.47  ?  15  VAL D CB    1 
ATOM 4134 C CG1   . VAL C 1 15  ? 158.080 143.987 101.680 1.00 37.47  ?  15  VAL D CG1   1 
ATOM 4135 C CG2   . VAL C 1 15  ? 157.052 143.166 99.566  1.00 37.47  ?  15  VAL D CG2   1 
ATOM 4136 N N     . LEU C 1 16  ? 155.287 144.253 103.656 1.00 39.08  ?  16  LEU D N     1 
ATOM 4137 C CA    . LEU C 1 16  ? 155.323 144.616 105.067 1.00 39.08  ?  16  LEU D CA    1 
ATOM 4138 C C     . LEU C 1 16  ? 154.578 143.604 105.923 1.00 39.08  ?  16  LEU D C     1 
ATOM 4139 O O     . LEU C 1 16  ? 154.975 143.339 107.063 1.00 39.08  ?  16  LEU D O     1 
ATOM 4140 C CB    . LEU C 1 16  ? 154.752 146.016 105.270 1.00 39.08  ?  16  LEU D CB    1 
ATOM 4141 C CG    . LEU C 1 16  ? 155.814 147.104 105.395 1.00 39.08  ?  16  LEU D CG    1 
ATOM 4142 C CD1   . LEU C 1 16  ? 156.385 147.041 106.792 1.00 39.08  ?  16  LEU D CD1   1 
ATOM 4143 C CD2   . LEU C 1 16  ? 156.913 146.953 104.358 1.00 39.08  ?  16  LEU D CD2   1 
ATOM 4144 N N     . GLU C 1 17  ? 153.490 143.033 105.401 1.00 43.85  ?  17  GLU D N     1 
ATOM 4145 C CA    . GLU C 1 17  ? 152.812 141.968 106.129 1.00 43.85  ?  17  GLU D CA    1 
ATOM 4146 C C     . GLU C 1 17  ? 153.722 140.758 106.293 1.00 43.85  ?  17  GLU D C     1 
ATOM 4147 O O     . GLU C 1 17  ? 153.751 140.129 107.357 1.00 43.85  ?  17  GLU D O     1 
ATOM 4148 C CB    . GLU C 1 17  ? 151.520 141.580 105.411 1.00 43.85  ?  17  GLU D CB    1 
ATOM 4149 C CG    . GLU C 1 17  ? 150.986 140.206 105.783 1.00 43.85  ?  17  GLU D CG    1 
ATOM 4150 C CD    . GLU C 1 17  ? 150.596 140.099 107.246 1.00 43.85  ?  17  GLU D CD    1 
ATOM 4151 O OE1   . GLU C 1 17  ? 150.306 141.143 107.868 1.00 43.85  ?  17  GLU D OE1   1 
ATOM 4152 O OE2   . GLU C 1 17  ? 150.581 138.969 107.776 1.00 43.85  -1 17  GLU D OE2   1 
ATOM 4153 N N     . ALA C 1 18  ? 154.476 140.419 105.246 1.00 40.97  ?  18  ALA D N     1 
ATOM 4154 C CA    . ALA C 1 18  ? 155.383 139.281 105.321 1.00 40.97  ?  18  ALA D CA    1 
ATOM 4155 C C     . ALA C 1 18  ? 156.500 139.518 106.329 1.00 40.97  ?  18  ALA D C     1 
ATOM 4156 O O     . ALA C 1 18  ? 156.869 138.607 107.079 1.00 40.97  ?  18  ALA D O     1 
ATOM 4157 C CB    . ALA C 1 18  ? 155.966 138.984 103.940 1.00 40.97  ?  18  ALA D CB    1 
ATOM 4158 N N     . LEU C 1 19  ? 157.053 140.730 106.364 1.00 40.94  ?  19  LEU D N     1 
ATOM 4159 C CA    . LEU C 1 19  ? 158.214 141.007 107.201 1.00 40.94  ?  19  LEU D CA    1 
ATOM 4160 C C     . LEU C 1 19  ? 157.868 141.415 108.628 1.00 40.94  ?  19  LEU D C     1 
ATOM 4161 O O     . LEU C 1 19  ? 158.780 141.544 109.451 1.00 40.94  ?  19  LEU D O     1 
ATOM 4162 C CB    . LEU C 1 19  ? 159.072 142.108 106.569 1.00 40.94  ?  19  LEU D CB    1 
ATOM 4163 C CG    . LEU C 1 19  ? 159.767 141.774 105.252 1.00 40.94  ?  19  LEU D CG    1 
ATOM 4164 C CD1   . LEU C 1 19  ? 160.908 142.741 104.997 1.00 40.94  ?  19  LEU D CD1   1 
ATOM 4165 C CD2   . LEU C 1 19  ? 160.269 140.345 105.263 1.00 40.94  ?  19  LEU D CD2   1 
ATOM 4166 N N     . LYS C 1 20  ? 156.590 141.619 108.949 1.00 47.85  ?  20  LYS D N     1 
ATOM 4167 C CA    . LYS C 1 20  ? 156.250 142.191 110.247 1.00 47.85  ?  20  LYS D CA    1 
ATOM 4168 C C     . LYS C 1 20  ? 156.382 141.190 111.390 1.00 47.85  ?  20  LYS D C     1 
ATOM 4169 O O     . LYS C 1 20  ? 156.728 141.585 112.508 1.00 47.85  ?  20  LYS D O     1 
ATOM 4170 C CB    . LYS C 1 20  ? 154.834 142.774 110.215 1.00 47.85  ?  20  LYS D CB    1 
ATOM 4171 C CG    . LYS C 1 20  ? 153.717 141.758 110.369 1.00 47.85  ?  20  LYS D CG    1 
ATOM 4172 C CD    . LYS C 1 20  ? 152.403 142.437 110.703 1.00 47.85  ?  20  LYS D CD    1 
ATOM 4173 C CE    . LYS C 1 20  ? 151.326 141.419 111.032 1.00 47.85  ?  20  LYS D CE    1 
ATOM 4174 N NZ    . LYS C 1 20  ? 150.049 142.076 111.419 1.00 47.85  1  20  LYS D NZ    1 
ATOM 4175 N N     . ASP C 1 21  ? 156.121 139.909 111.145 1.00 50.95  ?  21  ASP D N     1 
ATOM 4176 C CA    . ASP C 1 21  ? 156.107 138.919 112.214 1.00 50.95  ?  21  ASP D CA    1 
ATOM 4177 C C     . ASP C 1 21  ? 157.443 138.214 112.397 1.00 50.95  ?  21  ASP D C     1 
ATOM 4178 O O     . ASP C 1 21  ? 157.560 137.365 113.286 1.00 50.95  ?  21  ASP D O     1 
ATOM 4179 C CB    . ASP C 1 21  ? 155.012 137.880 111.958 1.00 50.95  ?  21  ASP D CB    1 
ATOM 4180 C CG    . ASP C 1 21  ? 154.946 137.450 110.510 1.00 50.95  ?  21  ASP D CG    1 
ATOM 4181 O OD1   . ASP C 1 21  ? 155.907 137.726 109.762 1.00 50.95  ?  21  ASP D OD1   1 
ATOM 4182 O OD2   . ASP C 1 21  ? 153.932 136.835 110.118 1.00 50.95  -1 21  ASP D OD2   1 
ATOM 4183 N N     . LEU C 1 22  ? 158.448 138.540 111.588 1.00 49.97  ?  22  LEU D N     1 
ATOM 4184 C CA    . LEU C 1 22  ? 159.755 137.906 111.691 1.00 49.97  ?  22  LEU D CA    1 
ATOM 4185 C C     . LEU C 1 22  ? 160.872 138.868 112.053 1.00 49.97  ?  22  LEU D C     1 
ATOM 4186 O O     . LEU C 1 22  ? 161.825 138.462 112.719 1.00 49.97  ?  22  LEU D O     1 
ATOM 4187 C CB    . LEU C 1 22  ? 160.112 137.209 110.372 1.00 49.97  ?  22  LEU D CB    1 
ATOM 4188 C CG    . LEU C 1 22  ? 161.290 136.237 110.420 1.00 49.97  ?  22  LEU D CG    1 
ATOM 4189 C CD1   . LEU C 1 22  ? 161.071 135.190 111.497 1.00 49.97  ?  22  LEU D CD1   1 
ATOM 4190 C CD2   . LEU C 1 22  ? 161.498 135.580 109.067 1.00 49.97  ?  22  LEU D CD2   1 
ATOM 4191 N N     . ILE C 1 23  ? 160.777 140.127 111.637 1.00 50.73  ?  23  ILE D N     1 
ATOM 4192 C CA    . ILE C 1 23  ? 161.811 141.123 111.881 1.00 50.73  ?  23  ILE D CA    1 
ATOM 4193 C C     . ILE C 1 23  ? 161.153 142.366 112.457 1.00 50.73  ?  23  ILE D C     1 
ATOM 4194 O O     . ILE C 1 23  ? 160.124 142.821 111.946 1.00 50.73  ?  23  ILE D O     1 
ATOM 4195 C CB    . ILE C 1 23  ? 162.582 141.464 110.593 1.00 50.73  ?  23  ILE D CB    1 
ATOM 4196 C CG1   . ILE C 1 23  ? 163.394 140.257 110.133 1.00 50.73  ?  23  ILE D CG1   1 
ATOM 4197 C CG2   . ILE C 1 23  ? 163.487 142.660 110.805 1.00 50.73  ?  23  ILE D CG2   1 
ATOM 4198 C CD1   . ILE C 1 23  ? 163.887 140.377 108.727 1.00 50.73  ?  23  ILE D CD1   1 
ATOM 4199 N N     . ASN C 1 24  ? 161.741 142.912 113.518 1.00 57.73  ?  24  ASN D N     1 
ATOM 4200 C CA    . ASN C 1 24  ? 161.227 144.120 114.148 1.00 57.73  ?  24  ASN D CA    1 
ATOM 4201 C C     . ASN C 1 24  ? 161.912 145.386 113.654 1.00 57.73  ?  24  ASN D C     1 
ATOM 4202 O O     . ASN C 1 24  ? 161.236 146.387 113.401 1.00 57.73  ?  24  ASN D O     1 
ATOM 4203 C CB    . ASN C 1 24  ? 161.368 144.024 115.669 1.00 57.73  ?  24  ASN D CB    1 
ATOM 4204 C CG    . ASN C 1 24  ? 160.254 143.221 116.304 1.00 57.73  ?  24  ASN D CG    1 
ATOM 4205 O OD1   . ASN C 1 24  ? 159.165 143.098 115.743 1.00 57.73  ?  24  ASN D OD1   1 
ATOM 4206 N ND2   . ASN C 1 24  ? 160.519 142.669 117.482 1.00 57.73  ?  24  ASN D ND2   1 
ATOM 4207 N N     . GLU C 1 25  ? 163.235 145.372 113.514 1.00 58.36  ?  25  GLU D N     1 
ATOM 4208 C CA    . GLU C 1 25  ? 163.988 146.525 113.044 1.00 58.36  ?  25  GLU D CA    1 
ATOM 4209 C C     . GLU C 1 25  ? 164.853 146.121 111.860 1.00 58.36  ?  25  GLU D C     1 
ATOM 4210 O O     . GLU C 1 25  ? 165.428 145.028 111.844 1.00 58.36  ?  25  GLU D O     1 
ATOM 4211 C CB    . GLU C 1 25  ? 164.869 147.111 114.154 1.00 58.36  ?  25  GLU D CB    1 
ATOM 4212 C CG    . GLU C 1 25  ? 164.245 147.083 115.541 1.00 58.36  ?  25  GLU D CG    1 
ATOM 4213 C CD    . GLU C 1 25  ? 162.877 147.733 115.585 1.00 58.36  ?  25  GLU D CD    1 
ATOM 4214 O OE1   . GLU C 1 25  ? 162.708 148.812 114.982 1.00 58.36  ?  25  GLU D OE1   1 
ATOM 4215 O OE2   . GLU C 1 25  ? 161.967 147.162 116.219 1.00 58.36  -1 25  GLU D OE2   1 
ATOM 4216 N N     . ALA C 1 26  ? 164.950 147.008 110.873 1.00 51.45  ?  26  ALA D N     1 
ATOM 4217 C CA    . ALA C 1 26  ? 165.712 146.717 109.669 1.00 51.45  ?  26  ALA D CA    1 
ATOM 4218 C C     . ALA C 1 26  ? 166.329 148.001 109.139 1.00 51.45  ?  26  ALA D C     1 
ATOM 4219 O O     . ALA C 1 26  ? 165.925 149.106 109.506 1.00 51.45  ?  26  ALA D O     1 
ATOM 4220 C CB    . ALA C 1 26  ? 164.840 146.059 108.596 1.00 51.45  ?  26  ALA D CB    1 
ATOM 4221 N N     . CYS C 1 27  ? 167.320 147.837 108.268 1.00 50.30  ?  27  CYS D N     1 
ATOM 4222 C CA    . CYS C 1 27  ? 168.042 148.950 107.666 1.00 50.30  ?  27  CYS D CA    1 
ATOM 4223 C C     . CYS C 1 27  ? 167.850 148.899 106.158 1.00 50.30  ?  27  CYS D C     1 
ATOM 4224 O O     . CYS C 1 27  ? 168.260 147.931 105.511 1.00 50.30  ?  27  CYS D O     1 
ATOM 4225 C CB    . CYS C 1 27  ? 169.528 148.888 108.024 1.00 50.30  ?  27  CYS D CB    1 
ATOM 4226 S SG    . CYS C 1 27  ? 170.422 150.437 107.791 1.00 50.30  ?  27  CYS D SG    1 
ATOM 4227 N N     . TRP C 1 28  ? 167.236 149.941 105.602 1.00 45.88  ?  28  TRP D N     1 
ATOM 4228 C CA    . TRP C 1 28  ? 166.955 150.010 104.169 1.00 45.88  ?  28  TRP D CA    1 
ATOM 4229 C C     . TRP C 1 28  ? 168.131 150.687 103.478 1.00 45.88  ?  28  TRP D C     1 
ATOM 4230 O O     . TRP C 1 28  ? 168.219 151.916 103.440 1.00 45.88  ?  28  TRP D O     1 
ATOM 4231 C CB    . TRP C 1 28  ? 165.654 150.758 103.897 1.00 45.88  ?  28  TRP D CB    1 
ATOM 4232 C CG    . TRP C 1 28  ? 164.475 150.282 104.692 1.00 45.88  ?  28  TRP D CG    1 
ATOM 4233 C CD1   . TRP C 1 28  ? 164.352 150.259 106.049 1.00 45.88  ?  28  TRP D CD1   1 
ATOM 4234 C CD2   . TRP C 1 28  ? 163.248 149.762 104.171 1.00 45.88  ?  28  TRP D CD2   1 
ATOM 4235 N NE1   . TRP C 1 28  ? 163.127 149.754 106.406 1.00 45.88  ?  28  TRP D NE1   1 
ATOM 4236 C CE2   . TRP C 1 28  ? 162.430 149.441 105.270 1.00 45.88  ?  28  TRP D CE2   1 
ATOM 4237 C CE3   . TRP C 1 28  ? 162.763 149.534 102.881 1.00 45.88  ?  28  TRP D CE3   1 
ATOM 4238 C CZ2   . TRP C 1 28  ? 161.155 148.906 105.120 1.00 45.88  ?  28  TRP D CZ2   1 
ATOM 4239 C CZ3   . TRP C 1 28  ? 161.497 149.002 102.734 1.00 45.88  ?  28  TRP D CZ3   1 
ATOM 4240 C CH2   . TRP C 1 28  ? 160.707 148.694 103.846 1.00 45.88  ?  28  TRP D CH2   1 
ATOM 4241 N N     . ASP C 1 29  ? 169.034 149.887 102.923 1.00 46.92  ?  29  ASP D N     1 
ATOM 4242 C CA    . ASP C 1 29  ? 170.185 150.421 102.202 1.00 46.92  ?  29  ASP D CA    1 
ATOM 4243 C C     . ASP C 1 29  ? 169.709 150.956 100.859 1.00 46.92  ?  29  ASP D C     1 
ATOM 4244 O O     . ASP C 1 29  ? 169.635 150.222 99.873  1.00 46.92  ?  29  ASP D O     1 
ATOM 4245 C CB    . ASP C 1 29  ? 171.249 149.345 102.024 1.00 46.92  ?  29  ASP D CB    1 
ATOM 4246 C CG    . ASP C 1 29  ? 171.809 148.854 103.344 1.00 46.92  ?  29  ASP D CG    1 
ATOM 4247 O OD1   . ASP C 1 29  ? 172.028 149.690 104.245 1.00 46.92  ?  29  ASP D OD1   1 
ATOM 4248 O OD2   . ASP C 1 29  ? 172.032 147.634 103.483 1.00 46.92  -1 29  ASP D OD2   1 
ATOM 4249 N N     . ILE C 1 30  ? 169.388 152.245 100.816 1.00 50.00  ?  30  ILE D N     1 
ATOM 4250 C CA    . ILE C 1 30  ? 168.836 152.884 99.628  1.00 50.00  ?  30  ILE D CA    1 
ATOM 4251 C C     . ILE C 1 30  ? 169.980 153.387 98.763  1.00 50.00  ?  30  ILE D C     1 
ATOM 4252 O O     . ILE C 1 30  ? 170.881 154.080 99.252  1.00 50.00  ?  30  ILE D O     1 
ATOM 4253 C CB    . ILE C 1 30  ? 167.890 154.035 100.006 1.00 50.00  ?  30  ILE D CB    1 
ATOM 4254 C CG1   . ILE C 1 30  ? 166.776 153.528 100.922 1.00 50.00  ?  30  ILE D CG1   1 
ATOM 4255 C CG2   . ILE C 1 30  ? 167.318 154.682 98.757  1.00 50.00  ?  30  ILE D CG2   1 
ATOM 4256 C CD1   . ILE C 1 30  ? 165.649 152.840 100.194 1.00 50.00  ?  30  ILE D CD1   1 
ATOM 4257 N N     . SER C 1 31  ? 169.947 153.040 97.479  1.00 53.27  ?  31  SER D N     1 
ATOM 4258 C CA    . SER C 1 31  ? 170.938 153.498 96.520  1.00 53.27  ?  31  SER D CA    1 
ATOM 4259 C C     . SER C 1 31  ? 170.243 153.753 95.190  1.00 53.27  ?  31  SER D C     1 
ATOM 4260 O O     . SER C 1 31  ? 169.023 153.610 95.066  1.00 53.27  ?  31  SER D O     1 
ATOM 4261 C CB    . SER C 1 31  ? 172.075 152.483 96.365  1.00 53.27  ?  31  SER D CB    1 
ATOM 4262 O OG    . SER C 1 31  ? 171.622 151.310 95.713  1.00 53.27  ?  31  SER D OG    1 
ATOM 4263 N N     . SER C 1 32  ? 171.032 154.137 94.185  1.00 56.85  ?  32  SER D N     1 
ATOM 4264 C CA    . SER C 1 32  ? 170.465 154.397 92.866  1.00 56.85  ?  32  SER D CA    1 
ATOM 4265 C C     . SER C 1 32  ? 169.931 153.125 92.223  1.00 56.85  ?  32  SER D C     1 
ATOM 4266 O O     . SER C 1 32  ? 168.988 153.186 91.426  1.00 56.85  ?  32  SER D O     1 
ATOM 4267 C CB    . SER C 1 32  ? 171.511 155.047 91.962  1.00 56.85  ?  32  SER D CB    1 
ATOM 4268 O OG    . SER C 1 32  ? 171.124 154.964 90.602  1.00 56.85  ?  32  SER D OG    1 
ATOM 4269 N N     . SER C 1 33  ? 170.520 151.972 92.546  1.00 53.62  ?  33  SER D N     1 
ATOM 4270 C CA    . SER C 1 33  ? 170.045 150.714 91.980  1.00 53.62  ?  33  SER D CA    1 
ATOM 4271 C C     . SER C 1 33  ? 168.631 150.397 92.447  1.00 53.62  ?  33  SER D C     1 
ATOM 4272 O O     . SER C 1 33  ? 167.796 149.938 91.658  1.00 53.62  ?  33  SER D O     1 
ATOM 4273 C CB    . SER C 1 33  ? 170.998 149.579 92.350  1.00 53.62  ?  33  SER D CB    1 
ATOM 4274 O OG    . SER C 1 33  ? 170.938 149.300 93.738  1.00 53.62  ?  33  SER D OG    1 
ATOM 4275 N N     . GLY C 1 34  ? 168.342 150.630 93.719  1.00 45.15  ?  34  GLY D N     1 
ATOM 4276 C CA    . GLY C 1 34  ? 167.013 150.348 94.235  1.00 45.15  ?  34  GLY D CA    1 
ATOM 4277 C C     . GLY C 1 34  ? 167.027 150.279 95.753  1.00 45.15  ?  34  GLY D C     1 
ATOM 4278 O O     . GLY C 1 34  ? 167.841 150.929 96.409  1.00 45.15  ?  34  GLY D O     1 
ATOM 4279 N N     . VAL C 1 35  ? 166.108 149.479 96.284  1.00 36.14  ?  35  VAL D N     1 
ATOM 4280 C CA    . VAL C 1 35  ? 165.920 149.316 97.720  1.00 36.14  ?  35  VAL D CA    1 
ATOM 4281 C C     . VAL C 1 35  ? 166.454 147.950 98.123  1.00 36.14  ?  35  VAL D C     1 
ATOM 4282 O O     . VAL C 1 35  ? 166.152 146.943 97.473  1.00 36.14  ?  35  VAL D O     1 
ATOM 4283 C CB    . VAL C 1 35  ? 164.441 149.465 98.114  1.00 36.14  ?  35  VAL D CB    1 
ATOM 4284 C CG1   . VAL C 1 35  ? 164.272 149.290 99.610  1.00 36.14  ?  35  VAL D CG1   1 
ATOM 4285 C CG2   . VAL C 1 35  ? 163.912 150.812 97.667  1.00 36.14  ?  35  VAL D CG2   1 
ATOM 4286 N N     . ASN C 1 36  ? 167.244 147.917 99.193  1.00 36.21  ?  36  ASN D N     1 
ATOM 4287 C CA    . ASN C 1 36  ? 167.838 146.688 99.693  1.00 36.21  ?  36  ASN D CA    1 
ATOM 4288 C C     . ASN C 1 36  ? 167.570 146.573 101.186 1.00 36.21  ?  36  ASN D C     1 
ATOM 4289 O O     . ASN C 1 36  ? 167.409 147.579 101.882 1.00 36.21  ?  36  ASN D O     1 
ATOM 4290 C CB    . ASN C 1 36  ? 169.347 146.651 99.417  1.00 36.21  ?  36  ASN D CB    1 
ATOM 4291 C CG    . ASN C 1 36  ? 169.951 145.279 99.637  1.00 36.21  ?  36  ASN D CG    1 
ATOM 4292 O OD1   . ASN C 1 36  ? 169.462 144.490 100.445 1.00 36.21  ?  36  ASN D OD1   1 
ATOM 4293 N ND2   . ASN C 1 36  ? 171.023 144.985 98.912  1.00 36.21  ?  36  ASN D ND2   1 
ATOM 4294 N N     . LEU C 1 37  ? 167.521 145.335 101.672 1.00 34.97  ?  37  LEU D N     1 
ATOM 4295 C CA    . LEU C 1 37  ? 167.224 145.090 103.081 1.00 34.97  ?  37  LEU D CA    1 
ATOM 4296 C C     . LEU C 1 37  ? 167.757 143.714 103.453 1.00 34.97  ?  37  LEU D C     1 
ATOM 4297 O O     . LEU C 1 37  ? 167.231 142.703 102.981 1.00 34.97  ?  37  LEU D O     1 
ATOM 4298 C CB    . LEU C 1 37  ? 165.726 145.186 103.340 1.00 34.97  ?  37  LEU D CB    1 
ATOM 4299 C CG    . LEU C 1 37  ? 165.251 145.155 104.793 1.00 34.97  ?  37  LEU D CG    1 
ATOM 4300 C CD1   . LEU C 1 37  ? 164.021 146.028 104.951 1.00 34.97  ?  37  LEU D CD1   1 
ATOM 4301 C CD2   . LEU C 1 37  ? 164.952 143.740 105.252 1.00 34.97  ?  37  LEU D CD2   1 
ATOM 4302 N N     . GLN C 1 38  ? 168.785 143.677 104.296 1.00 41.54  ?  38  GLN D N     1 
ATOM 4303 C CA    . GLN C 1 38  ? 169.290 142.434 104.865 1.00 41.54  ?  38  GLN D CA    1 
ATOM 4304 C C     . GLN C 1 38  ? 169.318 142.587 106.375 1.00 41.54  ?  38  GLN D C     1 
ATOM 4305 O O     . GLN C 1 38  ? 169.956 143.509 106.893 1.00 41.54  ?  38  GLN D O     1 
ATOM 4306 C CB    . GLN C 1 38  ? 170.686 142.097 104.337 1.00 41.54  ?  38  GLN D CB    1 
ATOM 4307 C CG    . GLN C 1 38  ? 171.036 142.764 103.024 1.00 41.54  ?  38  GLN D CG    1 
ATOM 4308 C CD    . GLN C 1 38  ? 172.369 142.298 102.482 1.00 41.54  ?  38  GLN D CD    1 
ATOM 4309 O OE1   . GLN C 1 38  ? 173.008 141.415 103.053 1.00 41.54  ?  38  GLN D OE1   1 
ATOM 4310 N NE2   . GLN C 1 38  ? 172.798 142.889 101.374 1.00 41.54  ?  38  GLN D NE2   1 
ATOM 4311 N N     . SER C 1 39  ? 168.633 141.691 107.080 1.00 45.48  ?  39  SER D N     1 
ATOM 4312 C CA    . SER C 1 39  ? 168.551 141.797 108.533 1.00 45.48  ?  39  SER D CA    1 
ATOM 4313 C C     . SER C 1 39  ? 168.210 140.429 109.106 1.00 45.48  ?  39  SER D C     1 
ATOM 4314 O O     . SER C 1 39  ? 167.103 139.927 108.892 1.00 45.48  ?  39  SER D O     1 
ATOM 4315 C CB    . SER C 1 39  ? 167.515 142.835 108.937 1.00 45.48  ?  39  SER D CB    1 
ATOM 4316 O OG    . SER C 1 39  ? 166.229 142.469 108.474 1.00 45.48  ?  39  SER D OG    1 
ATOM 4317 N N     . MET C 1 40  ? 169.156 139.840 109.830 1.00 51.22  ?  40  MET D N     1 
ATOM 4318 C CA    . MET C 1 40  ? 168.905 138.583 110.518 1.00 51.22  ?  40  MET D CA    1 
ATOM 4319 C C     . MET C 1 40  ? 167.824 138.778 111.575 1.00 51.22  ?  40  MET D C     1 
ATOM 4320 O O     . MET C 1 40  ? 167.728 139.838 112.198 1.00 51.22  ?  40  MET D O     1 
ATOM 4321 C CB    . MET C 1 40  ? 170.203 138.074 111.147 1.00 51.22  ?  40  MET D CB    1 
ATOM 4322 C CG    . MET C 1 40  ? 170.109 136.737 111.851 1.00 51.22  ?  40  MET D CG    1 
ATOM 4323 S SD    . MET C 1 40  ? 171.596 136.404 112.815 1.00 51.22  ?  40  MET D SD    1 
ATOM 4324 C CE    . MET C 1 40  ? 172.835 136.363 111.525 1.00 51.22  ?  40  MET D CE    1 
ATOM 4325 N N     . ASP C 1 41  ? 166.999 137.752 111.767 1.00 57.03  ?  41  ASP D N     1 
ATOM 4326 C CA    . ASP C 1 41  ? 165.835 137.883 112.630 1.00 57.03  ?  41  ASP D CA    1 
ATOM 4327 C C     . ASP C 1 41  ? 166.252 138.046 114.092 1.00 57.03  ?  41  ASP D C     1 
ATOM 4328 O O     . ASP C 1 41  ? 167.434 137.999 114.446 1.00 57.03  ?  41  ASP D O     1 
ATOM 4329 C CB    . ASP C 1 41  ? 164.915 136.674 112.479 1.00 57.03  ?  41  ASP D CB    1 
ATOM 4330 C CG    . ASP C 1 41  ? 165.413 135.465 113.243 1.00 57.03  ?  41  ASP D CG    1 
ATOM 4331 O OD1   . ASP C 1 41  ? 166.634 135.207 113.224 1.00 57.03  ?  41  ASP D OD1   1 
ATOM 4332 O OD2   . ASP C 1 41  ? 164.581 134.776 113.870 1.00 57.03  -1 41  ASP D OD2   1 
ATOM 4333 N N     . SER C 1 42  ? 165.246 138.242 114.949 1.00 60.59  ?  42  SER D N     1 
ATOM 4334 C CA    . SER C 1 42  ? 165.506 138.467 116.369 1.00 60.59  ?  42  SER D CA    1 
ATOM 4335 C C     . SER C 1 42  ? 166.141 137.246 117.022 1.00 60.59  ?  42  SER D C     1 
ATOM 4336 O O     . SER C 1 42  ? 167.082 137.376 117.815 1.00 60.59  ?  42  SER D O     1 
ATOM 4337 C CB    . SER C 1 42  ? 164.207 138.840 117.083 1.00 60.59  ?  42  SER D CB    1 
ATOM 4338 O OG    . SER C 1 42  ? 163.605 137.701 117.670 1.00 60.59  ?  42  SER D OG    1 
ATOM 4339 N N     . SER C 1 43  ? 165.645 136.050 116.702 1.00 57.49  ?  43  SER D N     1 
ATOM 4340 C CA    . SER C 1 43  ? 166.199 134.831 117.276 1.00 57.49  ?  43  SER D CA    1 
ATOM 4341 C C     . SER C 1 43  ? 167.567 134.483 116.707 1.00 57.49  ?  43  SER D C     1 
ATOM 4342 O O     . SER C 1 43  ? 168.210 133.558 117.215 1.00 57.49  ?  43  SER D O     1 
ATOM 4343 C CB    . SER C 1 43  ? 165.238 133.663 117.060 1.00 57.49  ?  43  SER D CB    1 
ATOM 4344 O OG    . SER C 1 43  ? 164.965 133.475 115.683 1.00 57.49  ?  43  SER D OG    1 
ATOM 4345 N N     . HIS C 1 44  ? 168.015 135.192 115.670 1.00 56.70  ?  44  HIS D N     1 
ATOM 4346 C CA    . HIS C 1 44  ? 169.331 134.987 115.068 1.00 56.70  ?  44  HIS D CA    1 
ATOM 4347 C C     . HIS C 1 44  ? 169.489 133.561 114.544 1.00 56.70  ?  44  HIS D C     1 
ATOM 4348 O O     . HIS C 1 44  ? 170.509 132.903 114.754 1.00 56.70  ?  44  HIS D O     1 
ATOM 4349 C CB    . HIS C 1 44  ? 170.447 135.340 116.054 1.00 56.70  ?  44  HIS D CB    1 
ATOM 4350 C CG    . HIS C 1 44  ? 170.701 136.810 116.171 1.00 56.70  ?  44  HIS D CG    1 
ATOM 4351 N ND1   . HIS C 1 44  ? 171.725 137.444 115.501 1.00 56.70  ?  44  HIS D ND1   1 
ATOM 4352 C CD2   . HIS C 1 44  ? 170.060 137.772 116.877 1.00 56.70  ?  44  HIS D CD2   1 
ATOM 4353 C CE1   . HIS C 1 44  ? 171.706 138.733 115.791 1.00 56.70  ?  44  HIS D CE1   1 
ATOM 4354 N NE2   . HIS C 1 44  ? 170.705 138.958 116.624 1.00 56.70  ?  44  HIS D NE2   1 
ATOM 4355 N N     . VAL C 1 45  ? 168.455 133.083 113.851 1.00 52.43  ?  45  VAL D N     1 
ATOM 4356 C CA    . VAL C 1 45  ? 168.461 131.775 113.209 1.00 52.43  ?  45  VAL D CA    1 
ATOM 4357 C C     . VAL C 1 45  ? 168.238 131.892 111.706 1.00 52.43  ?  45  VAL D C     1 
ATOM 4358 O O     . VAL C 1 45  ? 168.950 131.273 110.910 1.00 52.43  ?  45  VAL D O     1 
ATOM 4359 C CB    . VAL C 1 45  ? 167.414 130.832 113.841 1.00 52.43  ?  45  VAL D CB    1 
ATOM 4360 C CG1   . VAL C 1 45  ? 167.578 129.424 113.297 1.00 52.43  ?  45  VAL D CG1   1 
ATOM 4361 C CG2   . VAL C 1 45  ? 167.530 130.844 115.355 1.00 52.43  ?  45  VAL D CG2   1 
ATOM 4362 N N     . SER C 1 46  ? 167.254 132.686 111.299 1.00 48.61  ?  46  SER D N     1 
ATOM 4363 C CA    . SER C 1 46  ? 166.908 132.871 109.900 1.00 48.61  ?  46  SER D CA    1 
ATOM 4364 C C     . SER C 1 46  ? 167.340 134.250 109.422 1.00 48.61  ?  46  SER D C     1 
ATOM 4365 O O     . SER C 1 46  ? 167.457 135.197 110.203 1.00 48.61  ?  46  SER D O     1 
ATOM 4366 C CB    . SER C 1 46  ? 165.402 132.697 109.681 1.00 48.61  ?  46  SER D CB    1 
ATOM 4367 O OG    . SER C 1 46  ? 164.695 133.851 110.095 1.00 48.61  ?  46  SER D OG    1 
ATOM 4368 N N     . LEU C 1 47  ? 167.572 134.351 108.118 1.00 44.16  ?  47  LEU D N     1 
ATOM 4369 C CA    . LEU C 1 47  ? 167.974 135.593 107.478 1.00 44.16  ?  47  LEU D CA    1 
ATOM 4370 C C     . LEU C 1 47  ? 166.976 135.930 106.381 1.00 44.16  ?  47  LEU D C     1 
ATOM 4371 O O     . LEU C 1 47  ? 166.446 135.035 105.717 1.00 44.16  ?  47  LEU D O     1 
ATOM 4372 C CB    . LEU C 1 47  ? 169.402 135.481 106.917 1.00 44.16  ?  47  LEU D CB    1 
ATOM 4373 C CG    . LEU C 1 47  ? 170.020 136.547 106.006 1.00 44.16  ?  47  LEU D CG    1 
ATOM 4374 C CD1   . LEU C 1 47  ? 171.530 136.437 106.073 1.00 44.16  ?  47  LEU D CD1   1 
ATOM 4375 C CD2   . LEU C 1 47  ? 169.579 136.400 104.558 1.00 44.16  ?  47  LEU D CD2   1 
ATOM 4376 N N     . VAL C 1 48  ? 166.721 137.222 106.195 1.00 54.26  ?  48  VAL D N     1 
ATOM 4377 C CA    . VAL C 1 48  ? 165.768 137.704 105.202 1.00 54.26  ?  48  VAL D CA    1 
ATOM 4378 C C     . VAL C 1 48  ? 166.467 138.715 104.307 1.00 54.26  ?  48  VAL D C     1 
ATOM 4379 O O     . VAL C 1 48  ? 167.128 139.634 104.800 1.00 54.26  ?  48  VAL D O     1 
ATOM 4380 C CB    . VAL C 1 48  ? 164.528 138.334 105.861 1.00 54.26  ?  48  VAL D CB    1 
ATOM 4381 C CG1   . VAL C 1 48  ? 163.683 139.046 104.824 1.00 54.26  ?  48  VAL D CG1   1 
ATOM 4382 C CG2   . VAL C 1 48  ? 163.717 137.275 106.580 1.00 54.26  ?  48  VAL D CG2   1 
ATOM 4383 N N     . GLN C 1 49  ? 166.318 138.546 102.998 1.00 31.61  ?  49  GLN D N     1 
ATOM 4384 C CA    . GLN C 1 49  ? 166.882 139.457 102.015 1.00 31.61  ?  49  GLN D CA    1 
ATOM 4385 C C     . GLN C 1 49  ? 165.754 140.024 101.168 1.00 31.61  ?  49  GLN D C     1 
ATOM 4386 O O     . GLN C 1 49  ? 164.680 139.428 101.062 1.00 31.61  ?  49  GLN D O     1 
ATOM 4387 C CB    . GLN C 1 49  ? 167.909 138.749 101.128 1.00 31.61  ?  49  GLN D CB    1 
ATOM 4388 C CG    . GLN C 1 49  ? 169.068 139.620 100.689 1.00 31.61  ?  49  GLN D CG    1 
ATOM 4389 C CD    . GLN C 1 49  ? 168.803 140.324 99.378  1.00 31.61  ?  49  GLN D CD    1 
ATOM 4390 O OE1   . GLN C 1 49  ? 167.689 140.294 98.858  1.00 31.61  ?  49  GLN D OE1   1 
ATOM 4391 N NE2   . GLN C 1 49  ? 169.831 140.956 98.829  1.00 31.61  ?  49  GLN D NE2   1 
ATOM 4392 N N     . LEU C 1 50  ? 165.999 141.187 100.571 1.00 35.03  ?  50  LEU D N     1 
ATOM 4393 C CA    . LEU C 1 50  ? 164.983 141.855 99.770  1.00 35.03  ?  50  LEU D CA    1 
ATOM 4394 C C     . LEU C 1 50  ? 165.665 142.772 98.769  1.00 35.03  ?  50  LEU D C     1 
ATOM 4395 O O     . LEU C 1 50  ? 166.720 143.340 99.058  1.00 35.03  ?  50  LEU D O     1 
ATOM 4396 C CB    . LEU C 1 50  ? 164.017 142.649 100.657 1.00 35.03  ?  50  LEU D CB    1 
ATOM 4397 C CG    . LEU C 1 50  ? 162.630 142.994 100.116 1.00 35.03  ?  50  LEU D CG    1 
ATOM 4398 C CD1   . LEU C 1 50  ? 161.671 143.198 101.269 1.00 35.03  ?  50  LEU D CD1   1 
ATOM 4399 C CD2   . LEU C 1 50  ? 162.667 144.240 99.254  1.00 35.03  ?  50  LEU D CD2   1 
ATOM 4400 N N     . THR C 1 51  ? 165.059 142.910 97.593  1.00 33.51  ?  51  THR D N     1 
ATOM 4401 C CA    . THR C 1 51  ? 165.590 143.785 96.558  1.00 33.51  ?  51  THR D CA    1 
ATOM 4402 C C     . THR C 1 51  ? 164.446 144.293 95.696  1.00 33.51  ?  51  THR D C     1 
ATOM 4403 O O     . THR C 1 51  ? 163.612 143.504 95.243  1.00 33.51  ?  51  THR D O     1 
ATOM 4404 C CB    . THR C 1 51  ? 166.621 143.056 95.689  1.00 33.51  ?  51  THR D CB    1 
ATOM 4405 O OG1   . THR C 1 51  ? 167.691 142.578 96.513  1.00 33.51  ?  51  THR D OG1   1 
ATOM 4406 C CG2   . THR C 1 51  ? 167.185 143.990 94.631  1.00 33.51  ?  51  THR D CG2   1 
ATOM 4407 N N     . LEU C 1 52  ? 164.409 145.605 95.477  1.00 40.93  ?  52  LEU D N     1 
ATOM 4408 C CA    . LEU C 1 52  ? 163.436 146.237 94.592  1.00 40.93  ?  52  LEU D CA    1 
ATOM 4409 C C     . LEU C 1 52  ? 164.195 147.161 93.652  1.00 40.93  ?  52  LEU D C     1 
ATOM 4410 O O     . LEU C 1 52  ? 164.695 148.207 94.077  1.00 40.93  ?  52  LEU D O     1 
ATOM 4411 C CB    . LEU C 1 52  ? 162.382 147.011 95.383  1.00 40.93  ?  52  LEU D CB    1 
ATOM 4412 C CG    . LEU C 1 52  ? 161.505 146.208 96.341  1.00 40.93  ?  52  LEU D CG    1 
ATOM 4413 C CD1   . LEU C 1 52  ? 160.554 147.125 97.088  1.00 40.93  ?  52  LEU D CD1   1 
ATOM 4414 C CD2   . LEU C 1 52  ? 160.737 145.144 95.586  1.00 40.93  ?  52  LEU D CD2   1 
ATOM 4415 N N     . ARG C 1 53  ? 164.283 146.780 92.382  1.00 48.52  ?  53  ARG D N     1 
ATOM 4416 C CA    . ARG C 1 53  ? 165.044 147.561 91.420  1.00 48.52  ?  53  ARG D CA    1 
ATOM 4417 C C     . ARG C 1 53  ? 164.380 148.910 91.167  1.00 48.52  ?  53  ARG D C     1 
ATOM 4418 O O     . ARG C 1 53  ? 163.165 149.069 91.312  1.00 48.52  ?  53  ARG D O     1 
ATOM 4419 C CB    . ARG C 1 53  ? 165.196 146.793 90.108  1.00 48.52  ?  53  ARG D CB    1 
ATOM 4420 C CG    . ARG C 1 53  ? 166.520 146.059 89.979  1.00 48.52  ?  53  ARG D CG    1 
ATOM 4421 C CD    . ARG C 1 53  ? 166.465 144.991 88.900  1.00 48.52  ?  53  ARG D CD    1 
ATOM 4422 N NE    . ARG C 1 53  ? 165.346 144.076 89.086  1.00 48.52  ?  53  ARG D NE    1 
ATOM 4423 C CZ    . ARG C 1 53  ? 164.355 143.920 88.220  1.00 48.52  ?  53  ARG D CZ    1 
ATOM 4424 N NH1   . ARG C 1 53  ? 164.309 144.609 87.091  1.00 48.52  1  53  ARG D NH1   1 
ATOM 4425 N NH2   . ARG C 1 53  ? 163.384 143.053 88.493  1.00 48.52  ?  53  ARG D NH2   1 
ATOM 4426 N N     . SER C 1 54  ? 165.201 149.892 90.790  1.00 56.28  ?  54  SER D N     1 
ATOM 4427 C CA    . SER C 1 54  ? 164.698 151.244 90.574  1.00 56.28  ?  54  SER D CA    1 
ATOM 4428 C C     . SER C 1 54  ? 163.736 151.314 89.395  1.00 56.28  ?  54  SER D C     1 
ATOM 4429 O O     . SER C 1 54  ? 162.822 152.145 89.396  1.00 56.28  ?  54  SER D O     1 
ATOM 4430 C CB    . SER C 1 54  ? 165.862 152.209 90.357  1.00 56.28  ?  54  SER D CB    1 
ATOM 4431 O OG    . SER C 1 54  ? 166.625 151.835 89.224  1.00 56.28  ?  54  SER D OG    1 
ATOM 4432 N N     . GLU C 1 55  ? 163.926 150.464 88.385  1.00 60.60  ?  55  GLU D N     1 
ATOM 4433 C CA    . GLU C 1 55  ? 163.055 150.500 87.215  1.00 60.60  ?  55  GLU D CA    1 
ATOM 4434 C C     . GLU C 1 55  ? 161.618 150.130 87.551  1.00 60.60  ?  55  GLU D C     1 
ATOM 4435 O O     . GLU C 1 55  ? 160.704 150.510 86.812  1.00 60.60  ?  55  GLU D O     1 
ATOM 4436 C CB    . GLU C 1 55  ? 163.592 149.565 86.131  1.00 60.60  ?  55  GLU D CB    1 
ATOM 4437 C CG    . GLU C 1 55  ? 164.888 150.037 85.494  1.00 60.60  ?  55  GLU D CG    1 
ATOM 4438 C CD    . GLU C 1 55  ? 166.112 149.410 86.130  1.00 60.60  ?  55  GLU D CD    1 
ATOM 4439 O OE1   . GLU C 1 55  ? 165.959 148.403 86.852  1.00 60.60  ?  55  GLU D OE1   1 
ATOM 4440 O OE2   . GLU C 1 55  ? 167.228 149.925 85.909  1.00 60.60  -1 55  GLU D OE2   1 
ATOM 4441 N N     . GLY C 1 56  ? 161.398 149.398 88.643  1.00 58.39  ?  56  GLY D N     1 
ATOM 4442 C CA    . GLY C 1 56  ? 160.044 149.012 89.000  1.00 58.39  ?  56  GLY D CA    1 
ATOM 4443 C C     . GLY C 1 56  ? 159.173 150.188 89.397  1.00 58.39  ?  56  GLY D C     1 
ATOM 4444 O O     . GLY C 1 56  ? 158.003 150.263 89.010  1.00 58.39  ?  56  GLY D O     1 
ATOM 4445 N N     . PHE C 1 57  ? 159.721 151.113 90.180  1.00 59.51  ?  57  PHE D N     1 
ATOM 4446 C CA    . PHE C 1 57  ? 158.962 152.283 90.598  1.00 59.51  ?  57  PHE D CA    1 
ATOM 4447 C C     . PHE C 1 57  ? 158.601 153.142 89.395  1.00 59.51  ?  57  PHE D C     1 
ATOM 4448 O O     . PHE C 1 57  ? 159.368 153.249 88.434  1.00 59.51  ?  57  PHE D O     1 
ATOM 4449 C CB    . PHE C 1 57  ? 159.761 153.112 91.601  1.00 59.51  ?  57  PHE D CB    1 
ATOM 4450 C CG    . PHE C 1 57  ? 160.175 152.354 92.826  1.00 59.51  ?  57  PHE D CG    1 
ATOM 4451 C CD1   . PHE C 1 57  ? 159.273 152.117 93.847  1.00 59.51  ?  57  PHE D CD1   1 
ATOM 4452 C CD2   . PHE C 1 57  ? 161.468 151.888 92.963  1.00 59.51  ?  57  PHE D CD2   1 
ATOM 4453 C CE1   . PHE C 1 57  ? 159.653 151.427 94.978  1.00 59.51  ?  57  PHE D CE1   1 
ATOM 4454 C CE2   . PHE C 1 57  ? 161.853 151.197 94.091  1.00 59.51  ?  57  PHE D CE2   1 
ATOM 4455 C CZ    . PHE C 1 57  ? 160.944 150.966 95.099  1.00 59.51  ?  57  PHE D CZ    1 
ATOM 4456 N N     . ASP C 1 58  ? 157.416 153.753 89.447  1.00 62.30  ?  58  ASP D N     1 
ATOM 4457 C CA    . ASP C 1 58  ? 157.014 154.660 88.379  1.00 62.30  ?  58  ASP D CA    1 
ATOM 4458 C C     . ASP C 1 58  ? 157.923 155.881 88.327  1.00 62.30  ?  58  ASP D C     1 
ATOM 4459 O O     . ASP C 1 58  ? 158.274 156.359 87.242  1.00 62.30  ?  58  ASP D O     1 
ATOM 4460 C CB    . ASP C 1 58  ? 155.558 155.080 88.563  1.00 62.30  ?  58  ASP D CB    1 
ATOM 4461 C CG    . ASP C 1 58  ? 154.886 155.431 87.253  1.00 62.30  ?  58  ASP D CG    1 
ATOM 4462 O OD1   . ASP C 1 58  ? 155.204 156.499 86.689  1.00 62.30  ?  58  ASP D OD1   1 
ATOM 4463 O OD2   . ASP C 1 58  ? 154.044 154.638 86.783  1.00 62.30  -1 58  ASP D OD2   1 
ATOM 4464 N N     . THR C 1 59  ? 158.308 156.402 89.488  1.00 57.80  ?  59  THR D N     1 
ATOM 4465 C CA    . THR C 1 59  ? 159.238 157.517 89.571  1.00 57.80  ?  59  THR D CA    1 
ATOM 4466 C C     . THR C 1 59  ? 160.208 157.264 90.713  1.00 57.80  ?  59  THR D C     1 
ATOM 4467 O O     . THR C 1 59  ? 159.800 156.850 91.801  1.00 57.80  ?  59  THR D O     1 
ATOM 4468 C CB    . THR C 1 59  ? 158.508 158.847 89.785  1.00 57.80  ?  59  THR D CB    1 
ATOM 4469 O OG1   . THR C 1 59  ? 157.398 158.933 88.884  1.00 57.80  ?  59  THR D OG1   1 
ATOM 4470 C CG2   . THR C 1 59  ? 159.447 160.015 89.534  1.00 57.80  ?  59  THR D CG2   1 
ATOM 4471 N N     . TYR C 1 60  ? 161.490 157.510 90.460  1.00 62.51  ?  60  TYR D N     1 
ATOM 4472 C CA    . TYR C 1 60  ? 162.529 157.263 91.448  1.00 62.51  ?  60  TYR D CA    1 
ATOM 4473 C C     . TYR C 1 60  ? 163.595 158.341 91.352  1.00 62.51  ?  60  TYR D C     1 
ATOM 4474 O O     . TYR C 1 60  ? 164.036 158.692 90.255  1.00 62.51  ?  60  TYR D O     1 
ATOM 4475 C CB    . TYR C 1 60  ? 163.160 155.881 91.250  1.00 62.51  ?  60  TYR D CB    1 
ATOM 4476 C CG    . TYR C 1 60  ? 163.931 155.377 92.445  1.00 62.51  ?  60  TYR D CG    1 
ATOM 4477 C CD1   . TYR C 1 60  ? 163.292 154.702 93.473  1.00 62.51  ?  60  TYR D CD1   1 
ATOM 4478 C CD2   . TYR C 1 60  ? 165.300 155.568 92.540  1.00 62.51  ?  60  TYR D CD2   1 
ATOM 4479 C CE1   . TYR C 1 60  ? 163.994 154.237 94.565  1.00 62.51  ?  60  TYR D CE1   1 
ATOM 4480 C CE2   . TYR C 1 60  ? 166.011 155.106 93.628  1.00 62.51  ?  60  TYR D CE2   1 
ATOM 4481 C CZ    . TYR C 1 60  ? 165.354 154.442 94.637  1.00 62.51  ?  60  TYR D CZ    1 
ATOM 4482 O OH    . TYR C 1 60  ? 166.062 153.982 95.722  1.00 62.51  ?  60  TYR D OH    1 
ATOM 4483 N N     . ARG C 1 61  ? 164.012 158.853 92.510  1.00 77.01  ?  61  ARG D N     1 
ATOM 4484 C CA    . ARG C 1 61  ? 165.072 159.860 92.576  1.00 77.01  ?  61  ARG D CA    1 
ATOM 4485 C C     . ARG C 1 61  ? 165.797 159.668 93.905  1.00 77.01  ?  61  ARG D C     1 
ATOM 4486 O O     . ARG C 1 61  ? 165.210 159.880 94.971  1.00 77.01  ?  61  ARG D O     1 
ATOM 4487 C CB    . ARG C 1 61  ? 164.515 161.271 92.446  1.00 77.01  ?  61  ARG D CB    1 
ATOM 4488 C CG    . ARG C 1 61  ? 164.279 161.726 91.014  1.00 77.01  ?  61  ARG D CG    1 
ATOM 4489 C CD    . ARG C 1 61  ? 164.269 163.249 90.863  1.00 77.01  ?  61  ARG D CD    1 
ATOM 4490 N NE    . ARG C 1 61  ? 165.073 163.945 91.863  1.00 77.01  ?  61  ARG D NE    1 
ATOM 4491 C CZ    . ARG C 1 61  ? 164.585 164.522 92.953  1.00 77.01  ?  61  ARG D CZ    1 
ATOM 4492 N NH1   . ARG C 1 61  ? 163.290 164.503 93.224  1.00 77.01  1  61  ARG D NH1   1 
ATOM 4493 N NH2   . ARG C 1 61  ? 165.417 165.134 93.791  1.00 77.01  ?  61  ARG D NH2   1 
ATOM 4494 N N     . CYS C 1 62  ? 167.065 159.272 93.833  1.00 79.22  ?  62  CYS D N     1 
ATOM 4495 C CA    . CYS C 1 62  ? 167.898 159.046 95.013  1.00 79.22  ?  62  CYS D CA    1 
ATOM 4496 C C     . CYS C 1 62  ? 169.275 159.633 94.724  1.00 79.22  ?  62  CYS D C     1 
ATOM 4497 O O     . CYS C 1 62  ? 170.081 159.026 94.013  1.00 79.22  ?  62  CYS D O     1 
ATOM 4498 C CB    . CYS C 1 62  ? 167.981 157.563 95.351  1.00 79.22  ?  62  CYS D CB    1 
ATOM 4499 S SG    . CYS C 1 62  ? 169.359 157.113 96.424  1.00 79.22  ?  62  CYS D SG    1 
ATOM 4500 N N     . ASP C 1 63  ? 169.538 160.822 95.270  1.00 85.30  ?  63  ASP D N     1 
ATOM 4501 C CA    . ASP C 1 63  ? 170.805 161.494 95.001  1.00 85.30  ?  63  ASP D CA    1 
ATOM 4502 C C     . ASP C 1 63  ? 171.961 160.820 95.727  1.00 85.30  ?  63  ASP D C     1 
ATOM 4503 O O     . ASP C 1 63  ? 173.024 160.594 95.138  1.00 85.30  ?  63  ASP D O     1 
ATOM 4504 C CB    . ASP C 1 63  ? 170.707 162.966 95.397  1.00 85.30  ?  63  ASP D CB    1 
ATOM 4505 C CG    . ASP C 1 63  ? 169.667 163.716 94.591  1.00 85.30  ?  63  ASP D CG    1 
ATOM 4506 O OD1   . ASP C 1 63  ? 169.376 163.291 93.454  1.00 85.30  ?  63  ASP D OD1   1 
ATOM 4507 O OD2   . ASP C 1 63  ? 169.136 164.727 95.096  1.00 85.30  -1 63  ASP D OD2   1 
ATOM 4508 N N     . ARG C 1 64  ? 171.773 160.488 97.002  1.00 85.61  ?  64  ARG D N     1 
ATOM 4509 C CA    . ARG C 1 64  ? 172.826 159.910 97.822  1.00 85.61  ?  64  ARG D CA    1 
ATOM 4510 C C     . ARG C 1 64  ? 172.305 158.664 98.521  1.00 85.61  ?  64  ARG D C     1 
ATOM 4511 O O     . ARG C 1 64  ? 171.097 158.476 98.684  1.00 85.61  ?  64  ARG D O     1 
ATOM 4512 C CB    . ARG C 1 64  ? 173.346 160.908 98.865  1.00 85.61  ?  64  ARG D CB    1 
ATOM 4513 C CG    . ARG C 1 64  ? 173.108 162.367 98.514  1.00 85.61  ?  64  ARG D CG    1 
ATOM 4514 C CD    . ARG C 1 64  ? 173.546 163.326 99.624  1.00 85.61  ?  64  ARG D CD    1 
ATOM 4515 N NE    . ARG C 1 64  ? 173.023 162.976 100.941 1.00 85.61  ?  64  ARG D NE    1 
ATOM 4516 C CZ    . ARG C 1 64  ? 173.665 162.240 101.839 1.00 85.61  ?  64  ARG D CZ    1 
ATOM 4517 N NH1   . ARG C 1 64  ? 174.877 161.764 101.604 1.00 85.61  1  64  ARG D NH1   1 
ATOM 4518 N NH2   . ARG C 1 64  ? 173.078 161.979 103.003 1.00 85.61  ?  64  ARG D NH2   1 
ATOM 4519 N N     . ASN C 1 65  ? 173.236 157.808 98.931  1.00 74.53  ?  65  ASN D N     1 
ATOM 4520 C CA    . ASN C 1 65  ? 172.886 156.595 99.656  1.00 74.53  ?  65  ASN D CA    1 
ATOM 4521 C C     . ASN C 1 65  ? 172.568 156.930 101.107 1.00 74.53  ?  65  ASN D C     1 
ATOM 4522 O O     . ASN C 1 65  ? 173.296 157.691 101.751 1.00 74.53  ?  65  ASN D O     1 
ATOM 4523 C CB    . ASN C 1 65  ? 174.031 155.587 99.585  1.00 74.53  ?  65  ASN D CB    1 
ATOM 4524 C CG    . ASN C 1 65  ? 174.647 155.507 98.205  1.00 74.53  ?  65  ASN D CG    1 
ATOM 4525 O OD1   . ASN C 1 65  ? 174.020 155.874 97.211  1.00 74.53  ?  65  ASN D OD1   1 
ATOM 4526 N ND2   . ASN C 1 65  ? 175.883 155.028 98.136  1.00 74.53  ?  65  ASN D ND2   1 
ATOM 4527 N N     . LEU C 1 66  ? 171.481 156.361 101.622 1.00 61.35  ?  66  LEU D N     1 
ATOM 4528 C CA    . LEU C 1 66  ? 171.062 156.581 102.998 1.00 61.35  ?  66  LEU D CA    1 
ATOM 4529 C C     . LEU C 1 66  ? 170.910 155.236 103.697 1.00 61.35  ?  66  LEU D C     1 
ATOM 4530 O O     . LEU C 1 66  ? 171.167 154.176 103.121 1.00 61.35  ?  66  LEU D O     1 
ATOM 4531 C CB    . LEU C 1 66  ? 169.746 157.368 103.076 1.00 61.35  ?  66  LEU D CB    1 
ATOM 4532 C CG    . LEU C 1 66  ? 169.490 158.545 102.134 1.00 61.35  ?  66  LEU D CG    1 
ATOM 4533 C CD1   . LEU C 1 66  ? 168.859 158.067 100.837 1.00 61.35  ?  66  LEU D CD1   1 
ATOM 4534 C CD2   . LEU C 1 66  ? 168.611 159.585 102.808 1.00 61.35  ?  66  LEU D CD2   1 
ATOM 4535 N N     . ALA C 1 67  ? 170.493 155.289 104.961 1.00 52.25  ?  67  ALA D N     1 
ATOM 4536 C CA    . ALA C 1 67  ? 170.203 154.079 105.726 1.00 52.25  ?  67  ALA D CA    1 
ATOM 4537 C C     . ALA C 1 67  ? 169.111 154.429 106.733 1.00 52.25  ?  67  ALA D C     1 
ATOM 4538 O O     . ALA C 1 67  ? 169.409 154.916 107.827 1.00 52.25  ?  67  ALA D O     1 
ATOM 4539 C CB    . ALA C 1 67  ? 171.453 153.549 106.414 1.00 52.25  ?  67  ALA D CB    1 
ATOM 4540 N N     . MET C 1 68  ? 167.859 154.176 106.362 1.00 55.67  ?  68  MET D N     1 
ATOM 4541 C CA    . MET C 1 68  ? 166.718 154.487 107.215 1.00 55.67  ?  68  MET D CA    1 
ATOM 4542 C C     . MET C 1 68  ? 166.435 153.297 108.123 1.00 55.67  ?  68  MET D C     1 
ATOM 4543 O O     . MET C 1 68  ? 165.891 152.283 107.678 1.00 55.67  ?  68  MET D O     1 
ATOM 4544 C CB    . MET C 1 68  ? 165.488 154.831 106.379 1.00 55.67  ?  68  MET D CB    1 
ATOM 4545 C CG    . MET C 1 68  ? 165.424 156.275 105.922 1.00 55.67  ?  68  MET D CG    1 
ATOM 4546 S SD    . MET C 1 68  ? 164.878 156.439 104.216 1.00 55.67  ?  68  MET D SD    1 
ATOM 4547 C CE    . MET C 1 68  ? 166.417 156.163 103.352 1.00 55.67  ?  68  MET D CE    1 
ATOM 4548 N N     . GLY C 1 69  ? 166.798 153.422 109.395 1.00 64.36  ?  69  GLY D N     1 
ATOM 4549 C CA    . GLY C 1 69  ? 166.454 152.401 110.362 1.00 64.36  ?  69  GLY D CA    1 
ATOM 4550 C C     . GLY C 1 69  ? 165.090 152.661 110.963 1.00 64.36  ?  69  GLY D C     1 
ATOM 4551 O O     . GLY C 1 69  ? 164.955 153.480 111.877 1.00 64.36  ?  69  GLY D O     1 
ATOM 4552 N N     . VAL C 1 70  ? 164.070 151.971 110.461 1.00 53.76  ?  70  VAL D N     1 
ATOM 4553 C CA    . VAL C 1 70  ? 162.689 152.236 110.840 1.00 53.76  ?  70  VAL D CA    1 
ATOM 4554 C C     . VAL C 1 70  ? 162.111 151.013 111.533 1.00 53.76  ?  70  VAL D C     1 
ATOM 4555 O O     . VAL C 1 70  ? 162.580 149.885 111.348 1.00 53.76  ?  70  VAL D O     1 
ATOM 4556 C CB    . VAL C 1 70  ? 161.831 152.627 109.619 1.00 53.76  ?  70  VAL D CB    1 
ATOM 4557 C CG1   . VAL C 1 70  ? 162.590 153.595 108.731 1.00 53.76  ?  70  VAL D CG1   1 
ATOM 4558 C CG2   . VAL C 1 70  ? 161.425 151.391 108.839 1.00 53.76  ?  70  VAL D CG2   1 
ATOM 4559 N N     . ASN C 1 71  ? 161.089 151.248 112.351 1.00 52.52  ?  71  ASN D N     1 
ATOM 4560 C CA    . ASN C 1 71  ? 160.414 150.157 113.037 1.00 52.52  ?  71  ASN D CA    1 
ATOM 4561 C C     . ASN C 1 71  ? 159.475 149.443 112.075 1.00 52.52  ?  71  ASN D C     1 
ATOM 4562 O O     . ASN C 1 71  ? 158.597 150.065 111.471 1.00 52.52  ?  71  ASN D O     1 
ATOM 4563 C CB    . ASN C 1 71  ? 159.643 150.686 114.244 1.00 52.52  ?  71  ASN D CB    1 
ATOM 4564 C CG    . ASN C 1 71  ? 159.274 149.593 115.228 1.00 52.52  ?  71  ASN D CG    1 
ATOM 4565 O OD1   . ASN C 1 71  ? 158.920 148.481 114.837 1.00 52.52  ?  71  ASN D OD1   1 
ATOM 4566 N ND2   . ASN C 1 71  ? 159.357 149.905 116.515 1.00 52.52  ?  71  ASN D ND2   1 
ATOM 4567 N N     . LEU C 1 72  ? 159.660 148.130 111.935 1.00 49.14  ?  72  LEU D N     1 
ATOM 4568 C CA    . LEU C 1 72  ? 158.858 147.372 110.982 1.00 49.14  ?  72  LEU D CA    1 
ATOM 4569 C C     . LEU C 1 72  ? 157.420 147.222 111.459 1.00 49.14  ?  72  LEU D C     1 
ATOM 4570 O O     . LEU C 1 72  ? 156.486 147.269 110.651 1.00 49.14  ?  72  LEU D O     1 
ATOM 4571 C CB    . LEU C 1 72  ? 159.489 146.004 110.736 1.00 49.14  ?  72  LEU D CB    1 
ATOM 4572 C CG    . LEU C 1 72  ? 160.352 145.894 109.479 1.00 49.14  ?  72  LEU D CG    1 
ATOM 4573 C CD1   . LEU C 1 72  ? 159.490 145.964 108.240 1.00 49.14  ?  72  LEU D CD1   1 
ATOM 4574 C CD2   . LEU C 1 72  ? 161.408 146.984 109.450 1.00 49.14  ?  72  LEU D CD2   1 
ATOM 4575 N N     . THR C 1 73  ? 157.220 147.035 112.766 1.00 47.41  ?  73  THR D N     1 
ATOM 4576 C CA    . THR C 1 73  ? 155.865 146.890 113.287 1.00 47.41  ?  73  THR D CA    1 
ATOM 4577 C C     . THR C 1 73  ? 155.053 148.162 113.077 1.00 47.41  ?  73  THR D C     1 
ATOM 4578 O O     . THR C 1 73  ? 153.893 148.106 112.653 1.00 47.41  ?  73  THR D O     1 
ATOM 4579 C CB    . THR C 1 73  ? 155.907 146.525 114.770 1.00 47.41  ?  73  THR D CB    1 
ATOM 4580 O OG1   . THR C 1 73  ? 156.842 145.459 114.974 1.00 47.41  ?  73  THR D OG1   1 
ATOM 4581 C CG2   . THR C 1 73  ? 154.533 146.085 115.246 1.00 47.41  ?  73  THR D CG2   1 
ATOM 4582 N N     . SER C 1 74  ? 155.651 149.320 113.357 1.00 46.90  ?  74  SER D N     1 
ATOM 4583 C CA    . SER C 1 74  ? 154.945 150.580 113.155 1.00 46.90  ?  74  SER D CA    1 
ATOM 4584 C C     . SER C 1 74  ? 154.685 150.838 111.677 1.00 46.90  ?  74  SER D C     1 
ATOM 4585 O O     . SER C 1 74  ? 153.626 151.361 111.309 1.00 46.90  ?  74  SER D O     1 
ATOM 4586 C CB    . SER C 1 74  ? 155.738 151.728 113.774 1.00 46.90  ?  74  SER D CB    1 
ATOM 4587 O OG    . SER C 1 74  ? 156.078 151.439 115.117 1.00 46.90  ?  74  SER D OG    1 
ATOM 4588 N N     . MET C 1 75  ? 155.642 150.489 110.814 1.00 43.14  ?  75  MET D N     1 
ATOM 4589 C CA    . MET C 1 75  ? 155.426 150.653 109.382 1.00 43.14  ?  75  MET D CA    1 
ATOM 4590 C C     . MET C 1 75  ? 154.276 149.780 108.904 1.00 43.14  ?  75  MET D C     1 
ATOM 4591 O O     . MET C 1 75  ? 153.453 150.216 108.093 1.00 43.14  ?  75  MET D O     1 
ATOM 4592 C CB    . MET C 1 75  ? 156.704 150.329 108.609 1.00 43.14  ?  75  MET D CB    1 
ATOM 4593 C CG    . MET C 1 75  ? 156.567 150.508 107.107 1.00 43.14  ?  75  MET D CG    1 
ATOM 4594 S SD    . MET C 1 75  ? 158.071 151.099 106.312 1.00 43.14  ?  75  MET D SD    1 
ATOM 4595 C CE    . MET C 1 75  ? 158.263 152.688 107.105 1.00 43.14  ?  75  MET D CE    1 
ATOM 4596 N N     . SER C 1 76  ? 154.202 148.543 109.398 1.00 40.63  ?  76  SER D N     1 
ATOM 4597 C CA    . SER C 1 76  ? 153.080 147.678 109.053 1.00 40.63  ?  76  SER D CA    1 
ATOM 4598 C C     . SER C 1 76  ? 151.767 148.254 109.564 1.00 40.63  ?  76  SER D C     1 
ATOM 4599 O O     . SER C 1 76  ? 150.747 148.213 108.865 1.00 40.63  ?  76  SER D O     1 
ATOM 4600 C CB    . SER C 1 76  ? 153.305 146.278 109.619 1.00 40.63  ?  76  SER D CB    1 
ATOM 4601 O OG    . SER C 1 76  ? 152.077 145.591 109.772 1.00 40.63  ?  76  SER D OG    1 
ATOM 4602 N N     . LYS C 1 77  ? 151.774 148.796 110.784 1.00 40.80  ?  77  LYS D N     1 
ATOM 4603 C CA    . LYS C 1 77  ? 150.561 149.387 111.340 1.00 40.80  ?  77  LYS D CA    1 
ATOM 4604 C C     . LYS C 1 77  ? 150.078 150.554 110.491 1.00 40.80  ?  77  LYS D C     1 
ATOM 4605 O O     . LYS C 1 77  ? 148.876 150.691 110.235 1.00 40.80  ?  77  LYS D O     1 
ATOM 4606 C CB    . LYS C 1 77  ? 150.813 149.841 112.777 1.00 40.80  ?  77  LYS D CB    1 
ATOM 4607 C CG    . LYS C 1 77  ? 149.570 150.312 113.503 1.00 40.80  ?  77  LYS D CG    1 
ATOM 4608 C CD    . LYS C 1 77  ? 148.638 149.151 113.796 1.00 40.80  ?  77  LYS D CD    1 
ATOM 4609 C CE    . LYS C 1 77  ? 149.333 148.095 114.637 1.00 40.80  ?  77  LYS D CE    1 
ATOM 4610 N NZ    . LYS C 1 77  ? 149.794 148.644 115.941 1.00 40.80  1  77  LYS D NZ    1 
ATOM 4611 N N     . ILE C 1 78  ? 151.000 151.409 110.049 1.00 36.31  ?  78  ILE D N     1 
ATOM 4612 C CA    . ILE C 1 78  ? 150.621 152.533 109.199 1.00 36.31  ?  78  ILE D CA    1 
ATOM 4613 C C     . ILE C 1 78  ? 150.131 152.040 107.842 1.00 36.31  ?  78  ILE D C     1 
ATOM 4614 O O     . ILE C 1 78  ? 149.103 152.504 107.334 1.00 36.31  ?  78  ILE D O     1 
ATOM 4615 C CB    . ILE C 1 78  ? 151.797 153.516 109.057 1.00 36.31  ?  78  ILE D CB    1 
ATOM 4616 C CG1   . ILE C 1 78  ? 151.790 154.523 110.205 1.00 36.31  ?  78  ILE D CG1   1 
ATOM 4617 C CG2   . ILE C 1 78  ? 151.734 154.245 107.727 1.00 36.31  ?  78  ILE D CG2   1 
ATOM 4618 C CD1   . ILE C 1 78  ? 152.916 155.527 110.136 1.00 36.31  ?  78  ILE D CD1   1 
ATOM 4619 N N     . LEU C 1 79  ? 150.846 151.086 107.242 1.00 37.62  ?  79  LEU D N     1 
ATOM 4620 C CA    . LEU C 1 79  ? 150.500 150.616 105.905 1.00 37.62  ?  79  LEU D CA    1 
ATOM 4621 C C     . LEU C 1 79  ? 149.156 149.906 105.882 1.00 37.62  ?  79  LEU D C     1 
ATOM 4622 O O     . LEU C 1 79  ? 148.457 149.942 104.863 1.00 37.62  ?  79  LEU D O     1 
ATOM 4623 C CB    . LEU C 1 79  ? 151.591 149.687 105.379 1.00 37.62  ?  79  LEU D CB    1 
ATOM 4624 C CG    . LEU C 1 79  ? 152.555 150.296 104.363 1.00 37.62  ?  79  LEU D CG    1 
ATOM 4625 C CD1   . LEU C 1 79  ? 151.812 150.646 103.095 1.00 37.62  ?  79  LEU D CD1   1 
ATOM 4626 C CD2   . LEU C 1 79  ? 153.235 151.518 104.940 1.00 37.62  ?  79  LEU D CD2   1 
ATOM 4627 N N     . LYS C 1 80  ? 148.781 149.249 106.982 1.00 41.31  ?  80  LYS D N     1 
ATOM 4628 C CA    . LYS C 1 80  ? 147.488 148.577 107.029 1.00 41.31  ?  80  LYS D CA    1 
ATOM 4629 C C     . LYS C 1 80  ? 146.340 149.563 106.856 1.00 41.31  ?  80  LYS D C     1 
ATOM 4630 O O     . LYS C 1 80  ? 145.283 149.200 106.329 1.00 41.31  ?  80  LYS D O     1 
ATOM 4631 C CB    . LYS C 1 80  ? 147.352 147.811 108.345 1.00 41.31  ?  80  LYS D CB    1 
ATOM 4632 C CG    . LYS C 1 80  ? 146.023 147.104 108.527 1.00 41.31  ?  80  LYS D CG    1 
ATOM 4633 C CD    . LYS C 1 80  ? 145.440 147.391 109.897 1.00 41.31  ?  80  LYS D CD    1 
ATOM 4634 C CE    . LYS C 1 80  ? 145.456 148.882 110.190 1.00 41.31  ?  80  LYS D CE    1 
ATOM 4635 N NZ    . LYS C 1 80  ? 144.369 149.600 109.469 1.00 41.31  1  80  LYS D NZ    1 
ATOM 4636 N N     . CYS C 1 81  ? 146.536 150.816 107.270 1.00 43.44  ?  81  CYS D N     1 
ATOM 4637 C CA    . CYS C 1 81  ? 145.499 151.832 107.141 1.00 43.44  ?  81  CYS D CA    1 
ATOM 4638 C C     . CYS C 1 81  ? 145.266 152.266 105.699 1.00 43.44  ?  81  CYS D C     1 
ATOM 4639 O O     . CYS C 1 81  ? 144.303 152.995 105.441 1.00 43.44  ?  81  CYS D O     1 
ATOM 4640 C CB    . CYS C 1 81  ? 145.852 153.050 107.996 1.00 43.44  ?  81  CYS D CB    1 
ATOM 4641 S SG    . CYS C 1 81  ? 146.011 152.698 109.762 1.00 43.44  ?  81  CYS D SG    1 
ATOM 4642 N N     . ALA C 1 82  ? 146.111 151.848 104.764 1.00 46.36  ?  82  ALA D N     1 
ATOM 4643 C CA    . ALA C 1 82  ? 145.963 152.224 103.368 1.00 46.36  ?  82  ALA D CA    1 
ATOM 4644 C C     . ALA C 1 82  ? 145.136 151.193 102.612 1.00 46.36  ?  82  ALA D C     1 
ATOM 4645 O O     . ALA C 1 82  ? 145.146 150.002 102.934 1.00 46.36  ?  82  ALA D O     1 
ATOM 4646 C CB    . ALA C 1 82  ? 147.329 152.373 102.700 1.00 46.36  ?  82  ALA D CB    1 
ATOM 4647 N N     . GLY C 1 83  ? 144.418 151.665 101.599 1.00 53.56  ?  83  GLY D N     1 
ATOM 4648 C CA    . GLY C 1 83  ? 143.670 150.775 100.737 1.00 53.56  ?  83  GLY D CA    1 
ATOM 4649 C C     . GLY C 1 83  ? 144.575 150.007 99.793  1.00 53.56  ?  83  GLY D C     1 
ATOM 4650 O O     . GLY C 1 83  ? 145.765 150.288 99.643  1.00 53.56  ?  83  GLY D O     1 
ATOM 4651 N N     . ASN C 1 84  ? 143.988 149.009 99.136  1.00 61.40  ?  84  ASN D N     1 
ATOM 4652 C CA    . ASN C 1 84  ? 144.749 148.133 98.255  1.00 61.40  ?  84  ASN D CA    1 
ATOM 4653 C C     . ASN C 1 84  ? 144.936 148.702 96.856  1.00 61.40  ?  84  ASN D C     1 
ATOM 4654 O O     . ASN C 1 84  ? 145.622 148.077 96.041  1.00 61.40  ?  84  ASN D O     1 
ATOM 4655 C CB    . ASN C 1 84  ? 144.069 146.766 98.164  1.00 61.40  ?  84  ASN D CB    1 
ATOM 4656 C CG    . ASN C 1 84  ? 142.568 146.874 98.007  1.00 61.40  ?  84  ASN D CG    1 
ATOM 4657 O OD1   . ASN C 1 84  ? 142.050 147.900 97.566  1.00 61.40  ?  84  ASN D OD1   1 
ATOM 4658 N ND2   . ASN C 1 84  ? 141.857 145.813 98.372  1.00 61.40  ?  84  ASN D ND2   1 
ATOM 4659 N N     . GLU C 1 85  ? 144.348 149.860 96.555  1.00 65.21  ?  85  GLU D N     1 
ATOM 4660 C CA    . GLU C 1 85  ? 144.446 150.463 95.231  1.00 65.21  ?  85  GLU D CA    1 
ATOM 4661 C C     . GLU C 1 85  ? 145.061 151.857 95.276  1.00 65.21  ?  85  GLU D C     1 
ATOM 4662 O O     . GLU C 1 85  ? 144.893 152.635 94.332  1.00 65.21  ?  85  GLU D O     1 
ATOM 4663 C CB    . GLU C 1 85  ? 143.068 150.511 94.570  1.00 65.21  ?  85  GLU D CB    1 
ATOM 4664 C CG    . GLU C 1 85  ? 141.962 150.992 95.494  1.00 65.21  ?  85  GLU D CG    1 
ATOM 4665 C CD    . GLU C 1 85  ? 140.665 151.266 94.760  1.00 65.21  ?  85  GLU D CD    1 
ATOM 4666 O OE1   . GLU C 1 85  ? 140.377 150.556 93.774  1.00 65.21  ?  85  GLU D OE1   1 
ATOM 4667 O OE2   . GLU C 1 85  ? 139.934 152.192 95.170  1.00 65.21  -1 85  GLU D OE2   1 
ATOM 4668 N N     . ASP C 1 86  ? 145.772 152.187 96.348  1.00 53.80  ?  86  ASP D N     1 
ATOM 4669 C CA    . ASP C 1 86  ? 146.343 153.514 96.496  1.00 53.80  ?  86  ASP D CA    1 
ATOM 4670 C C     . ASP C 1 86  ? 147.646 153.634 95.710  1.00 53.80  ?  86  ASP D C     1 
ATOM 4671 O O     . ASP C 1 86  ? 148.168 152.662 95.158  1.00 53.80  ?  86  ASP D O     1 
ATOM 4672 C CB    . ASP C 1 86  ? 146.582 153.830 97.969  1.00 53.80  ?  86  ASP D CB    1 
ATOM 4673 C CG    . ASP C 1 86  ? 145.423 153.411 98.848  1.00 53.80  ?  86  ASP D CG    1 
ATOM 4674 O OD1   . ASP C 1 86  ? 144.283 153.354 98.342  1.00 53.80  ?  86  ASP D OD1   1 
ATOM 4675 O OD2   . ASP C 1 86  ? 145.650 153.145 100.046 1.00 53.80  -1 86  ASP D OD2   1 
ATOM 4676 N N     . ILE C 1 87  ? 148.169 154.851 95.661  1.00 43.34  ?  87  ILE D N     1 
ATOM 4677 C CA    . ILE C 1 87  ? 149.430 155.149 94.986  1.00 43.34  ?  87  ILE D CA    1 
ATOM 4678 C C     . ILE C 1 87  ? 150.374 155.692 96.052  1.00 43.34  ?  87  ILE D C     1 
ATOM 4679 O O     . ILE C 1 87  ? 150.409 156.894 96.328  1.00 43.34  ?  87  ILE D O     1 
ATOM 4680 C CB    . ILE C 1 87  ? 149.257 156.137 93.832  1.00 43.34  ?  87  ILE D CB    1 
ATOM 4681 C CG1   . ILE C 1 87  ? 147.945 155.870 93.096  1.00 43.34  ?  87  ILE D CG1   1 
ATOM 4682 C CG2   . ILE C 1 87  ? 150.425 156.045 92.873  1.00 43.34  ?  87  ILE D CG2   1 
ATOM 4683 C CD1   . ILE C 1 87  ? 147.698 156.808 91.937  1.00 43.34  ?  87  ILE D CD1   1 
ATOM 4684 N N     . ILE C 1 88  ? 151.158 154.801 96.658  1.00 38.42  ?  88  ILE D N     1 
ATOM 4685 C CA    . ILE C 1 88  ? 152.060 155.202 97.728  1.00 38.42  ?  88  ILE D CA    1 
ATOM 4686 C C     . ILE C 1 88  ? 153.200 156.032 97.157  1.00 38.42  ?  88  ILE D C     1 
ATOM 4687 O O     . ILE C 1 88  ? 153.726 155.741 96.075  1.00 38.42  ?  88  ILE D O     1 
ATOM 4688 C CB    . ILE C 1 88  ? 152.584 153.964 98.469  1.00 38.42  ?  88  ILE D CB    1 
ATOM 4689 C CG1   . ILE C 1 88  ? 151.422 153.028 98.794  1.00 38.42  ?  88  ILE D CG1   1 
ATOM 4690 C CG2   . ILE C 1 88  ? 153.319 154.372 99.730  1.00 38.42  ?  88  ILE D CG2   1 
ATOM 4691 C CD1   . ILE C 1 88  ? 151.775 151.926 99.743  1.00 38.42  ?  88  ILE D CD1   1 
ATOM 4692 N N     . THR C 1 89  ? 153.588 157.074 97.886  1.00 39.00  ?  89  THR D N     1 
ATOM 4693 C CA    . THR C 1 89  ? 154.588 158.035 97.434  1.00 39.00  ?  89  THR D CA    1 
ATOM 4694 C C     . THR C 1 89  ? 155.592 158.274 98.569  1.00 39.00  ?  89  THR D C     1 
ATOM 4695 O O     . THR C 1 89  ? 155.706 159.358 99.144  1.00 39.00  ?  89  THR D O     1 
ATOM 4696 C CB    . THR C 1 89  ? 153.877 159.288 96.901  1.00 39.00  ?  89  THR D CB    1 
ATOM 4697 O OG1   . THR C 1 89  ? 153.438 159.023 95.565  1.00 39.00  ?  89  THR D OG1   1 
ATOM 4698 C CG2   . THR C 1 89  ? 154.812 160.489 96.774  1.00 39.00  ?  89  THR D CG2   1 
ATOM 4699 N N     . LEU C 1 90  ? 156.235 157.190 98.999  1.00 43.71  ?  90  LEU D N     1 
ATOM 4700 C CA    . LEU C 1 90  ? 157.275 157.252 100.020 1.00 43.71  ?  90  LEU D CA    1 
ATOM 4701 C C     . LEU C 1 90  ? 158.262 158.371 99.727  1.00 43.71  ?  90  LEU D C     1 
ATOM 4702 O O     . LEU C 1 90  ? 158.775 158.488 98.613  1.00 43.71  ?  90  LEU D O     1 
ATOM 4703 C CB    . LEU C 1 90  ? 158.017 155.916 100.095 1.00 43.71  ?  90  LEU D CB    1 
ATOM 4704 C CG    . LEU C 1 90  ? 157.260 154.722 100.662 1.00 43.71  ?  90  LEU D CG    1 
ATOM 4705 C CD1   . LEU C 1 90  ? 157.963 153.432 100.285 1.00 43.71  ?  90  LEU D CD1   1 
ATOM 4706 C CD2   . LEU C 1 90  ? 157.143 154.844 102.165 1.00 43.71  ?  90  LEU D CD2   1 
ATOM 4707 N N     . ARG C 1 91  ? 158.519 159.199 100.736 1.00 52.94  ?  91  ARG D N     1 
ATOM 4708 C CA    . ARG C 1 91  ? 159.405 160.340 100.586 1.00 52.94  ?  91  ARG D CA    1 
ATOM 4709 C C     . ARG C 1 91  ? 160.159 160.573 101.885 1.00 52.94  ?  91  ARG D C     1 
ATOM 4710 O O     . ARG C 1 91  ? 159.657 160.285 102.974 1.00 52.94  ?  91  ARG D O     1 
ATOM 4711 C CB    . ARG C 1 91  ? 158.631 161.602 100.192 1.00 52.94  ?  91  ARG D CB    1 
ATOM 4712 C CG    . ARG C 1 91  ? 159.506 162.724 99.671  1.00 52.94  ?  91  ARG D CG    1 
ATOM 4713 C CD    . ARG C 1 91  ? 158.809 164.066 99.781  1.00 52.94  ?  91  ARG D CD    1 
ATOM 4714 N NE    . ARG C 1 91  ? 157.985 164.344 98.612  1.00 52.94  ?  91  ARG D NE    1 
ATOM 4715 C CZ    . ARG C 1 91  ? 156.685 164.096 98.535  1.00 52.94  ?  91  ARG D CZ    1 
ATOM 4716 N NH1   . ARG C 1 91  ? 156.019 163.577 99.553  1.00 52.94  1  91  ARG D NH1   1 
ATOM 4717 N NH2   . ARG C 1 91  ? 156.036 164.379 97.410  1.00 52.94  ?  91  ARG D NH2   1 
ATOM 4718 N N     . ALA C 1 92  ? 161.374 161.102 101.755 1.00 72.38  ?  92  ALA D N     1 
ATOM 4719 C CA    . ALA C 1 92  ? 162.207 161.426 102.904 1.00 72.38  ?  92  ALA D CA    1 
ATOM 4720 C C     . ALA C 1 92  ? 163.171 162.532 102.509 1.00 72.38  ?  92  ALA D C     1 
ATOM 4721 O O     . ALA C 1 92  ? 163.818 162.446 101.461 1.00 72.38  ?  92  ALA D O     1 
ATOM 4722 C CB    . ALA C 1 92  ? 162.978 160.199 103.397 1.00 72.38  ?  92  ALA D CB    1 
ATOM 4723 N N     . GLU C 1 93  ? 163.262 163.563 103.344 1.00 95.70  ?  93  GLU D N     1 
ATOM 4724 C CA    . GLU C 1 93  ? 164.159 164.673 103.072 1.00 95.70  ?  93  GLU D CA    1 
ATOM 4725 C C     . GLU C 1 93  ? 165.613 164.230 103.220 1.00 95.70  ?  93  GLU D C     1 
ATOM 4726 O O     . GLU C 1 93  ? 165.925 163.246 103.895 1.00 95.70  ?  93  GLU D O     1 
ATOM 4727 C CB    . GLU C 1 93  ? 163.857 165.842 104.012 1.00 95.70  ?  93  GLU D CB    1 
ATOM 4728 C CG    . GLU C 1 93  ? 164.495 167.162 103.610 1.00 95.70  ?  93  GLU D CG    1 
ATOM 4729 C CD    . GLU C 1 93  ? 164.426 167.409 102.117 1.00 95.70  ?  93  GLU D CD    1 
ATOM 4730 O OE1   . GLU C 1 93  ? 163.305 167.428 101.567 1.00 95.70  ?  93  GLU D OE1   1 
ATOM 4731 O OE2   . GLU C 1 93  ? 165.494 167.580 101.493 1.00 95.70  -1 93  GLU D OE2   1 
ATOM 4732 N N     . ASP C 1 94  ? 166.510 164.971 102.560 1.00 102.99 ?  94  ASP D N     1 
ATOM 4733 C CA    . ASP C 1 94  ? 167.933 164.653 102.630 1.00 102.99 ?  94  ASP D CA    1 
ATOM 4734 C C     . ASP C 1 94  ? 168.429 164.658 104.070 1.00 102.99 ?  94  ASP D C     1 
ATOM 4735 O O     . ASP C 1 94  ? 169.261 163.826 104.451 1.00 102.99 ?  94  ASP D O     1 
ATOM 4736 C CB    . ASP C 1 94  ? 168.736 165.639 101.783 1.00 102.99 ?  94  ASP D CB    1 
ATOM 4737 C CG    . ASP C 1 94  ? 169.846 164.965 101.004 1.00 102.99 ?  94  ASP D CG    1 
ATOM 4738 O OD1   . ASP C 1 94  ? 169.808 163.724 100.866 1.00 102.99 ?  94  ASP D OD1   1 
ATOM 4739 O OD2   . ASP C 1 94  ? 170.758 165.675 100.531 1.00 102.99 -1 94  ASP D OD2   1 
ATOM 4740 N N     . ASN C 1 95  ? 167.932 165.585 104.883 1.00 102.41 ?  95  ASN D N     1 
ATOM 4741 C CA    . ASN C 1 95  ? 168.179 165.550 106.321 1.00 102.41 ?  95  ASN D CA    1 
ATOM 4742 C C     . ASN C 1 95  ? 167.336 164.427 106.909 1.00 102.41 ?  95  ASN D C     1 
ATOM 4743 O O     . ASN C 1 95  ? 166.143 164.598 107.166 1.00 102.41 ?  95  ASN D O     1 
ATOM 4744 C CB    . ASN C 1 95  ? 167.841 166.894 106.956 1.00 102.41 ?  95  ASN D CB    1 
ATOM 4745 C CG    . ASN C 1 95  ? 167.891 166.851 108.470 1.00 102.41 ?  95  ASN D CG    1 
ATOM 4746 O OD1   . ASN C 1 95  ? 167.030 167.414 109.146 1.00 102.41 ?  95  ASN D OD1   1 
ATOM 4747 N ND2   . ASN C 1 95  ? 168.901 166.180 109.010 1.00 102.41 ?  95  ASN D ND2   1 
ATOM 4748 N N     . ALA C 1 96  ? 167.955 163.269 107.118 1.00 97.60  ?  96  ALA D N     1 
ATOM 4749 C CA    . ALA C 1 96  ? 167.224 162.064 107.505 1.00 97.60  ?  96  ALA D CA    1 
ATOM 4750 C C     . ALA C 1 96  ? 166.717 162.220 108.931 1.00 97.60  ?  96  ALA D C     1 
ATOM 4751 O O     . ALA C 1 96  ? 167.448 161.992 109.897 1.00 97.60  ?  96  ALA D O     1 
ATOM 4752 C CB    . ALA C 1 96  ? 168.115 160.835 107.368 1.00 97.60  ?  96  ALA D CB    1 
ATOM 4753 N N     . ASP C 1 97  ? 165.453 162.615 109.064 1.00 82.64  ?  97  ASP D N     1 
ATOM 4754 C CA    . ASP C 1 97  ? 164.799 162.713 110.360 1.00 82.64  ?  97  ASP D CA    1 
ATOM 4755 C C     . ASP C 1 97  ? 163.403 162.117 110.391 1.00 82.64  ?  97  ASP D C     1 
ATOM 4756 O O     . ASP C 1 97  ? 162.944 161.734 111.474 1.00 82.64  ?  97  ASP D O     1 
ATOM 4757 C CB    . ASP C 1 97  ? 164.713 164.179 110.807 1.00 82.64  ?  97  ASP D CB    1 
ATOM 4758 C CG    . ASP C 1 97  ? 164.285 165.103 109.684 1.00 82.64  ?  97  ASP D CG    1 
ATOM 4759 O OD1   . ASP C 1 97  ? 163.743 164.604 108.675 1.00 82.64  ?  97  ASP D OD1   1 
ATOM 4760 O OD2   . ASP C 1 97  ? 164.488 166.329 109.809 1.00 82.64  -1 97  ASP D OD2   1 
ATOM 4761 N N     . THR C 1 98  ? 162.719 162.014 109.253 1.00 67.83  ?  98  THR D N     1 
ATOM 4762 C CA    . THR C 1 98  ? 161.335 161.569 109.219 1.00 67.83  ?  98  THR D CA    1 
ATOM 4763 C C     . THR C 1 98  ? 161.082 160.827 107.916 1.00 67.83  ?  98  THR D C     1 
ATOM 4764 O O     . THR C 1 98  ? 161.794 161.009 106.925 1.00 67.83  ?  98  THR D O     1 
ATOM 4765 C CB    . THR C 1 98  ? 160.361 162.747 109.342 1.00 67.83  ?  98  THR D CB    1 
ATOM 4766 O OG1   . THR C 1 98  ? 160.886 163.875 108.631 1.00 67.83  ?  98  THR D OG1   1 
ATOM 4767 C CG2   . THR C 1 98  ? 160.151 163.129 110.800 1.00 67.83  ?  98  THR D CG2   1 
ATOM 4768 N N     . LEU C 1 99  ? 160.049 159.988 107.927 1.00 54.00  ?  99  LEU D N     1 
ATOM 4769 C CA    . LEU C 1 99  ? 159.584 159.287 106.739 1.00 54.00  ?  99  LEU D CA    1 
ATOM 4770 C C     . LEU C 1 99  ? 158.158 159.725 106.443 1.00 54.00  ?  99  LEU D C     1 
ATOM 4771 O O     . LEU C 1 99  ? 157.307 159.724 107.338 1.00 54.00  ?  99  LEU D O     1 
ATOM 4772 C CB    . LEU C 1 99  ? 159.648 157.769 106.927 1.00 54.00  ?  99  LEU D CB    1 
ATOM 4773 C CG    . LEU C 1 99  ? 159.802 156.939 105.651 1.00 54.00  ?  99  LEU D CG    1 
ATOM 4774 C CD1   . LEU C 1 99  ? 160.793 157.590 104.704 1.00 54.00  ?  99  LEU D CD1   1 
ATOM 4775 C CD2   . LEU C 1 99  ? 160.235 155.524 105.983 1.00 54.00  ?  99  LEU D CD2   1 
ATOM 4776 N N     . ALA C 1 100 ? 157.901 160.096 105.193 1.00 41.09  ?  100 ALA D N     1 
ATOM 4777 C CA    . ALA C 1 100 ? 156.611 160.630 104.780 1.00 41.09  ?  100 ALA D CA    1 
ATOM 4778 C C     . ALA C 1 100 ? 155.929 159.657 103.830 1.00 41.09  ?  100 ALA D C     1 
ATOM 4779 O O     . ALA C 1 100 ? 156.573 159.106 102.932 1.00 41.09  ?  100 ALA D O     1 
ATOM 4780 C CB    . ALA C 1 100 ? 156.775 161.996 104.111 1.00 41.09  ?  100 ALA D CB    1 
ATOM 4781 N N     . LEU C 1 101 ? 154.631 159.450 104.032 1.00 26.54  ?  101 LEU D N     1 
ATOM 4782 C CA    . LEU C 1 101 ? 153.818 158.588 103.186 1.00 26.54  ?  101 LEU D CA    1 
ATOM 4783 C C     . LEU C 1 101 ? 152.621 159.386 102.690 1.00 26.54  ?  101 LEU D C     1 
ATOM 4784 O O     . LEU C 1 101 ? 151.942 160.049 103.480 1.00 26.54  ?  101 LEU D O     1 
ATOM 4785 C CB    . LEU C 1 101 ? 153.375 157.339 103.948 1.00 26.54  ?  101 LEU D CB    1 
ATOM 4786 C CG    . LEU C 1 101 ? 154.528 156.468 104.457 1.00 26.54  ?  101 LEU D CG    1 
ATOM 4787 C CD1   . LEU C 1 101 ? 154.865 156.797 105.899 1.00 26.54  ?  101 LEU D CD1   1 
ATOM 4788 C CD2   . LEU C 1 101 ? 154.202 154.997 104.317 1.00 26.54  ?  101 LEU D CD2   1 
ATOM 4789 N N     . VAL C 1 102 ? 152.370 159.327 101.385 1.00 33.75  ?  102 VAL D N     1 
ATOM 4790 C CA    . VAL C 1 102 ? 151.491 160.284 100.721 1.00 33.75  ?  102 VAL D CA    1 
ATOM 4791 C C     . VAL C 1 102 ? 150.378 159.483 100.034 1.00 33.75  ?  102 VAL D C     1 
ATOM 4792 O O     . VAL C 1 102 ? 150.015 159.733 98.879  1.00 33.75  ?  102 VAL D O     1 
ATOM 4793 C CB    . VAL C 1 102 ? 152.323 161.201 99.789  1.00 33.75  ?  102 VAL D CB    1 
ATOM 4794 C CG1   . VAL C 1 102 ? 151.497 162.020 98.784  1.00 33.75  ?  102 VAL D CG1   1 
ATOM 4795 C CG2   . VAL C 1 102 ? 153.194 162.129 100.624 1.00 33.75  ?  102 VAL D CG2   1 
ATOM 4796 N N     . PHE C 1 103 ? 149.897 158.440 100.715 1.00 34.33  ?  103 PHE D N     1 
ATOM 4797 C CA    . PHE C 1 103 ? 148.790 157.613 100.232 1.00 34.33  ?  103 PHE D CA    1 
ATOM 4798 C C     . PHE C 1 103 ? 147.739 158.448 99.513  1.00 34.33  ?  103 PHE D C     1 
ATOM 4799 O O     . PHE C 1 103 ? 147.260 159.455 100.040 1.00 34.33  ?  103 PHE D O     1 
ATOM 4800 C CB    . PHE C 1 103 ? 148.123 156.882 101.402 1.00 34.33  ?  103 PHE D CB    1 
ATOM 4801 C CG    . PHE C 1 103 ? 149.048 156.025 102.218 1.00 34.33  ?  103 PHE D CG    1 
ATOM 4802 C CD1   . PHE C 1 103 ? 150.338 155.755 101.806 1.00 34.33  ?  103 PHE D CD1   1 
ATOM 4803 C CD2   . PHE C 1 103 ? 148.618 155.508 103.426 1.00 34.33  ?  103 PHE D CD2   1 
ATOM 4804 C CE1   . PHE C 1 103 ? 151.170 154.972 102.572 1.00 34.33  ?  103 PHE D CE1   1 
ATOM 4805 C CE2   . PHE C 1 103 ? 149.447 154.727 104.196 1.00 34.33  ?  103 PHE D CE2   1 
ATOM 4806 C CZ    . PHE C 1 103 ? 150.724 154.459 103.770 1.00 34.33  ?  103 PHE D CZ    1 
ATOM 4807 N N     . GLU C 1 104 ? 147.380 158.022 98.308  1.00 50.60  ?  104 GLU D N     1 
ATOM 4808 C CA    . GLU C 1 104 ? 146.394 158.711 97.487  1.00 50.60  ?  104 GLU D CA    1 
ATOM 4809 C C     . GLU C 1 104 ? 145.208 157.785 97.225  1.00 50.60  ?  104 GLU D C     1 
ATOM 4810 O O     . GLU C 1 104 ? 145.096 156.701 97.802  1.00 50.60  ?  104 GLU D O     1 
ATOM 4811 C CB    . GLU C 1 104 ? 147.022 159.197 96.180  1.00 50.60  ?  104 GLU D CB    1 
ATOM 4812 C CG    . GLU C 1 104 ? 148.107 160.237 96.363  1.00 50.60  ?  104 GLU D CG    1 
ATOM 4813 C CD    . GLU C 1 104 ? 148.372 161.023 95.096  1.00 50.60  ?  104 GLU D CD    1 
ATOM 4814 O OE1   . GLU C 1 104 ? 147.471 161.083 94.234  1.00 50.60  ?  104 GLU D OE1   1 
ATOM 4815 O OE2   . GLU C 1 104 ? 149.482 161.579 94.961  1.00 50.60  -1 104 GLU D OE2   1 
ATOM 4816 N N     . ALA C 1 105 ? 144.312 158.230 96.351  1.00 64.75  ?  105 ALA D N     1 
ATOM 4817 C CA    . ALA C 1 105 ? 143.143 157.458 95.969  1.00 64.75  ?  105 ALA D CA    1 
ATOM 4818 C C     . ALA C 1 105 ? 142.996 157.460 94.456  1.00 64.75  ?  105 ALA D C     1 
ATOM 4819 O O     . ALA C 1 105 ? 143.412 158.413 93.789  1.00 64.75  ?  105 ALA D O     1 
ATOM 4820 C CB    . ALA C 1 105 ? 141.871 158.025 96.614  1.00 64.75  ?  105 ALA D CB    1 
ATOM 4821 N N     . PRO C 1 106 ? 142.417 156.400 93.886  1.00 77.23  ?  106 PRO D N     1 
ATOM 4822 C CA    . PRO C 1 106 ? 142.269 156.347 92.422  1.00 77.23  ?  106 PRO D CA    1 
ATOM 4823 C C     . PRO C 1 106 ? 141.389 157.446 91.853  1.00 77.23  ?  106 PRO D C     1 
ATOM 4824 O O     . PRO C 1 106 ? 141.529 157.784 90.671  1.00 77.23  ?  106 PRO D O     1 
ATOM 4825 C CB    . PRO C 1 106 ? 141.662 154.958 92.177  1.00 77.23  ?  106 PRO D CB    1 
ATOM 4826 C CG    . PRO C 1 106 ? 141.932 154.182 93.421  1.00 77.23  ?  106 PRO D CG    1 
ATOM 4827 C CD    . PRO C 1 106 ? 141.940 155.170 94.538  1.00 77.23  ?  106 PRO D CD    1 
ATOM 4828 N N     . ASN C 1 107 ? 140.481 158.007 92.647  1.00 78.93  ?  107 ASN D N     1 
ATOM 4829 C CA    . ASN C 1 107 ? 139.560 159.033 92.173  1.00 78.93  ?  107 ASN D CA    1 
ATOM 4830 C C     . ASN C 1 107 ? 140.093 160.447 92.364  1.00 78.93  ?  107 ASN D C     1 
ATOM 4831 O O     . ASN C 1 107 ? 139.347 161.402 92.120  1.00 78.93  ?  107 ASN D O     1 
ATOM 4832 C CB    . ASN C 1 107 ? 138.207 158.891 92.876  1.00 78.93  ?  107 ASN D CB    1 
ATOM 4833 C CG    . ASN C 1 107 ? 138.307 159.061 94.381  1.00 78.93  ?  107 ASN D CG    1 
ATOM 4834 O OD1   . ASN C 1 107 ? 139.397 159.208 94.931  1.00 78.93  ?  107 ASN D OD1   1 
ATOM 4835 N ND2   . ASN C 1 107 ? 137.163 159.043 95.054  1.00 78.93  ?  107 ASN D ND2   1 
ATOM 4836 N N     . GLN C 1 108 ? 141.365 160.591 92.752  1.00 79.92  ?  108 GLN D N     1 
ATOM 4837 C CA    . GLN C 1 108 ? 141.977 161.858 93.154  1.00 79.92  ?  108 GLN D CA    1 
ATOM 4838 C C     . GLN C 1 108 ? 140.994 162.757 93.896  1.00 79.92  ?  108 GLN D C     1 
ATOM 4839 O O     . GLN C 1 108 ? 140.864 163.942 93.577  1.00 79.92  ?  108 GLN D O     1 
ATOM 4840 C CB    . GLN C 1 108 ? 142.603 162.640 91.979  1.00 79.92  ?  108 GLN D CB    1 
ATOM 4841 C CG    . GLN C 1 108 ? 141.823 162.826 90.662  1.00 79.92  ?  108 GLN D CG    1 
ATOM 4842 C CD    . GLN C 1 108 ? 141.537 161.541 89.905  1.00 79.92  ?  108 GLN D CD    1 
ATOM 4843 O OE1   . GLN C 1 108 ? 141.984 160.463 90.291  1.00 79.92  ?  108 GLN D OE1   1 
ATOM 4844 N NE2   . GLN C 1 108 ? 140.780 161.654 88.820  1.00 79.92  ?  108 GLN D NE2   1 
ATOM 4845 N N     . GLU C 1 109 ? 140.297 162.202 94.888  1.00 68.85  ?  109 GLU D N     1 
ATOM 4846 C CA    . GLU C 1 109 ? 139.381 162.972 95.711  1.00 68.85  ?  109 GLU D CA    1 
ATOM 4847 C C     . GLU C 1 109 ? 139.720 162.941 97.192  1.00 68.85  ?  109 GLU D C     1 
ATOM 4848 O O     . GLU C 1 109 ? 139.085 163.665 97.967  1.00 68.85  ?  109 GLU D O     1 
ATOM 4849 C CB    . GLU C 1 109 ? 137.937 162.478 95.523  1.00 68.85  ?  109 GLU D CB    1 
ATOM 4850 C CG    . GLU C 1 109 ? 137.330 162.825 94.172  1.00 68.85  ?  109 GLU D CG    1 
ATOM 4851 C CD    . GLU C 1 109 ? 137.044 164.308 94.014  1.00 68.85  ?  109 GLU D CD    1 
ATOM 4852 O OE1   . GLU C 1 109 ? 137.098 165.043 95.023  1.00 68.85  ?  109 GLU D OE1   1 
ATOM 4853 O OE2   . GLU C 1 109 ? 136.767 164.742 92.876  1.00 68.85  -1 109 GLU D OE2   1 
ATOM 4854 N N     . LYS C 1 110 ? 140.693 162.136 97.608  1.00 45.69  ?  110 LYS D N     1 
ATOM 4855 C CA    . LYS C 1 110 ? 141.044 162.020 99.018  1.00 45.69  ?  110 LYS D CA    1 
ATOM 4856 C C     . LYS C 1 110 ? 142.488 161.562 99.117  1.00 45.69  ?  110 LYS D C     1 
ATOM 4857 O O     . LYS C 1 110 ? 142.823 160.465 98.660  1.00 45.69  ?  110 LYS D O     1 
ATOM 4858 C CB    . LYS C 1 110 ? 140.113 161.040 99.731  1.00 45.69  ?  110 LYS D CB    1 
ATOM 4859 C CG    . LYS C 1 110 ? 140.687 160.437 100.996 1.00 45.69  ?  110 LYS D CG    1 
ATOM 4860 C CD    . LYS C 1 110 ? 139.772 159.356 101.533 1.00 45.69  ?  110 LYS D CD    1 
ATOM 4861 C CE    . LYS C 1 110 ? 140.468 158.519 102.584 1.00 45.69  ?  110 LYS D CE    1 
ATOM 4862 N NZ    . LYS C 1 110 ? 139.615 157.382 103.015 1.00 45.69  1  110 LYS D NZ    1 
ATOM 4863 N N     . VAL C 1 111 ? 143.338 162.398 99.701  1.00 35.90  ?  111 VAL D N     1 
ATOM 4864 C CA    . VAL C 1 111 ? 144.743 162.072 99.894  1.00 35.90  ?  111 VAL D CA    1 
ATOM 4865 C C     . VAL C 1 111 ? 145.006 161.942 101.385 1.00 35.90  ?  111 VAL D C     1 
ATOM 4866 O O     . VAL C 1 111 ? 144.289 162.507 102.217 1.00 35.90  ?  111 VAL D O     1 
ATOM 4867 C CB    . VAL C 1 111 ? 145.677 163.123 99.258  1.00 35.90  ?  111 VAL D CB    1 
ATOM 4868 C CG1   . VAL C 1 111 ? 145.191 163.486 97.866  1.00 35.90  ?  111 VAL D CG1   1 
ATOM 4869 C CG2   . VAL C 1 111 ? 145.773 164.359 100.135 1.00 35.90  ?  111 VAL D CG2   1 
ATOM 4870 N N     . SER C 1 112 ? 146.036 161.176 101.721 1.00 30.20  ?  112 SER D N     1 
ATOM 4871 C CA    . SER C 1 112 ? 146.425 160.960 103.104 1.00 30.20  ?  112 SER D CA    1 
ATOM 4872 C C     . SER C 1 112 ? 147.912 161.231 103.250 1.00 30.20  ?  112 SER D C     1 
ATOM 4873 O O     . SER C 1 112 ? 148.711 160.820 102.405 1.00 30.20  ?  112 SER D O     1 
ATOM 4874 C CB    . SER C 1 112 ? 146.104 159.535 103.556 1.00 30.20  ?  112 SER D CB    1 
ATOM 4875 O OG    . SER C 1 112 ? 144.772 159.188 103.228 1.00 30.20  ?  112 SER D OG    1 
ATOM 4876 N N     . ASP C 1 113 ? 148.278 161.924 104.321 1.00 30.59  ?  113 ASP D N     1 
ATOM 4877 C CA    . ASP C 1 113 ? 149.668 162.238 104.617 1.00 30.59  ?  113 ASP D CA    1 
ATOM 4878 C C     . ASP C 1 113 ? 150.012 161.681 105.989 1.00 30.59  ?  113 ASP D C     1 
ATOM 4879 O O     . ASP C 1 113 ? 149.229 161.822 106.932 1.00 30.59  ?  113 ASP D O     1 
ATOM 4880 C CB    . ASP C 1 113 ? 149.914 163.747 104.572 1.00 30.59  ?  113 ASP D CB    1 
ATOM 4881 C CG    . ASP C 1 113 ? 151.283 164.134 105.101 1.00 30.59  ?  113 ASP D CG    1 
ATOM 4882 O OD1   . ASP C 1 113 ? 152.213 163.303 105.035 1.00 30.59  ?  113 ASP D OD1   1 
ATOM 4883 O OD2   . ASP C 1 113 ? 151.431 165.276 105.585 1.00 30.59  -1 113 ASP D OD2   1 
ATOM 4884 N N     . TYR C 1 114 ? 151.175 161.048 106.094 1.00 29.61  ?  114 TYR D N     1 
ATOM 4885 C CA    . TYR C 1 114 ? 151.633 160.474 107.348 1.00 29.61  ?  114 TYR D CA    1 
ATOM 4886 C C     . TYR C 1 114 ? 153.100 160.824 107.541 1.00 29.61  ?  114 TYR D C     1 
ATOM 4887 O O     . TYR C 1 114 ? 153.813 161.149 106.590 1.00 29.61  ?  114 TYR D O     1 
ATOM 4888 C CB    . TYR C 1 114 ? 151.452 158.952 107.384 1.00 29.61  ?  114 TYR D CB    1 
ATOM 4889 C CG    . TYR C 1 114 ? 150.016 158.486 107.399 1.00 29.61  ?  114 TYR D CG    1 
ATOM 4890 C CD1   . TYR C 1 114 ? 149.234 158.538 106.255 1.00 29.61  ?  114 TYR D CD1   1 
ATOM 4891 C CD2   . TYR C 1 114 ? 149.448 157.977 108.555 1.00 29.61  ?  114 TYR D CD2   1 
ATOM 4892 C CE1   . TYR C 1 114 ? 147.927 158.108 106.266 1.00 29.61  ?  114 TYR D CE1   1 
ATOM 4893 C CE2   . TYR C 1 114 ? 148.140 157.543 108.575 1.00 29.61  ?  114 TYR D CE2   1 
ATOM 4894 C CZ    . TYR C 1 114 ? 147.385 157.610 107.428 1.00 29.61  ?  114 TYR D CZ    1 
ATOM 4895 O OH    . TYR C 1 114 ? 146.081 157.178 107.446 1.00 29.61  ?  114 TYR D OH    1 
ATOM 4896 N N     . GLU C 1 115 ? 153.543 160.758 108.791 1.00 45.57  ?  115 GLU D N     1 
ATOM 4897 C CA    . GLU C 1 115 ? 154.936 160.995 109.131 1.00 45.57  ?  115 GLU D CA    1 
ATOM 4898 C C     . GLU C 1 115 ? 155.409 159.922 110.099 1.00 45.57  ?  115 GLU D C     1 
ATOM 4899 O O     . GLU C 1 115 ? 154.615 159.332 110.836 1.00 45.57  ?  115 GLU D O     1 
ATOM 4900 C CB    . GLU C 1 115 ? 155.147 162.382 109.746 1.00 45.57  ?  115 GLU D CB    1 
ATOM 4901 C CG    . GLU C 1 115 ? 155.812 163.376 108.809 1.00 45.57  ?  115 GLU D CG    1 
ATOM 4902 C CD    . GLU C 1 115 ? 156.457 164.531 109.549 1.00 45.57  ?  115 GLU D CD    1 
ATOM 4903 O OE1   . GLU C 1 115 ? 156.540 164.470 110.793 1.00 45.57  ?  115 GLU D OE1   1 
ATOM 4904 O OE2   . GLU C 1 115 ? 156.885 165.499 108.886 1.00 45.57  -1 115 GLU D OE2   1 
ATOM 4905 N N     . MET C 1 116 ? 156.714 159.670 110.083 1.00 59.60  ?  116 MET D N     1 
ATOM 4906 C CA    . MET C 1 116 ? 157.321 158.647 110.916 1.00 59.60  ?  116 MET D CA    1 
ATOM 4907 C C     . MET C 1 116 ? 158.587 159.173 111.571 1.00 59.60  ?  116 MET D C     1 
ATOM 4908 O O     . MET C 1 116 ? 159.227 160.106 111.084 1.00 59.60  ?  116 MET D O     1 
ATOM 4909 C CB    . MET C 1 116 ? 157.656 157.389 110.118 1.00 59.60  ?  116 MET D CB    1 
ATOM 4910 C CG    . MET C 1 116 ? 157.256 156.120 110.821 1.00 59.60  ?  116 MET D CG    1 
ATOM 4911 S SD    . MET C 1 116 ? 157.008 154.741 109.705 1.00 59.60  ?  116 MET D SD    1 
ATOM 4912 C CE    . MET C 1 116 ? 157.033 153.409 110.891 1.00 59.60  ?  116 MET D CE    1 
ATOM 4913 N N     . LYS C 1 117 ? 158.939 158.553 112.692 1.00 67.10  ?  117 LYS D N     1 
ATOM 4914 C CA    . LYS C 1 117 ? 160.173 158.849 113.404 1.00 67.10  ?  117 LYS D CA    1 
ATOM 4915 C C     . LYS C 1 117 ? 161.184 157.751 113.102 1.00 67.10  ?  117 LYS D C     1 
ATOM 4916 O O     . LYS C 1 117 ? 160.953 156.582 113.430 1.00 67.10  ?  117 LYS D O     1 
ATOM 4917 C CB    . LYS C 1 117 ? 159.920 158.951 114.907 1.00 67.10  ?  117 LYS D CB    1 
ATOM 4918 C CG    . LYS C 1 117 ? 158.988 160.082 115.301 1.00 67.10  ?  117 LYS D CG    1 
ATOM 4919 C CD    . LYS C 1 117 ? 158.605 159.989 116.768 1.00 67.10  ?  117 LYS D CD    1 
ATOM 4920 C CE    . LYS C 1 117 ? 157.534 161.007 117.121 1.00 67.10  ?  117 LYS D CE    1 
ATOM 4921 N NZ    . LYS C 1 117 ? 156.977 160.782 118.483 1.00 67.10  1  117 LYS D NZ    1 
ATOM 4922 N N     . LEU C 1 118 ? 162.296 158.125 112.478 1.00 73.63  ?  118 LEU D N     1 
ATOM 4923 C CA    . LEU C 1 118 ? 163.344 157.166 112.174 1.00 73.63  ?  118 LEU D CA    1 
ATOM 4924 C C     . LEU C 1 118 ? 164.204 156.911 113.409 1.00 73.63  ?  118 LEU D C     1 
ATOM 4925 O O     . LEU C 1 118 ? 164.165 157.652 114.394 1.00 73.63  ?  118 LEU D O     1 
ATOM 4926 C CB    . LEU C 1 118 ? 164.214 157.665 111.023 1.00 73.63  ?  118 LEU D CB    1 
ATOM 4927 C CG    . LEU C 1 118 ? 163.535 158.501 109.939 1.00 73.63  ?  118 LEU D CG    1 
ATOM 4928 C CD1   . LEU C 1 118 ? 164.561 158.971 108.922 1.00 73.63  ?  118 LEU D CD1   1 
ATOM 4929 C CD2   . LEU C 1 118 ? 162.435 157.708 109.263 1.00 73.63  ?  118 LEU D CD2   1 
ATOM 4930 N N     . MET C 1 119 ? 164.992 155.841 113.348 1.00 81.25  ?  119 MET D N     1 
ATOM 4931 C CA    . MET C 1 119 ? 165.944 155.521 114.399 1.00 81.25  ?  119 MET D CA    1 
ATOM 4932 C C     . MET C 1 119 ? 167.310 155.263 113.784 1.00 81.25  ?  119 MET D C     1 
ATOM 4933 O O     . MET C 1 119 ? 167.434 154.947 112.598 1.00 81.25  ?  119 MET D O     1 
ATOM 4934 C CB    . MET C 1 119 ? 165.516 154.300 115.222 1.00 81.25  ?  119 MET D CB    1 
ATOM 4935 C CG    . MET C 1 119 ? 164.023 154.075 115.306 1.00 81.25  ?  119 MET D CG    1 
ATOM 4936 S SD    . MET C 1 119 ? 163.647 152.714 116.421 1.00 81.25  ?  119 MET D SD    1 
ATOM 4937 C CE    . MET C 1 119 ? 164.466 151.370 115.571 1.00 81.25  ?  119 MET D CE    1 
ATOM 4938 N N     . ASP C 1 120 ? 168.340 155.408 114.610 1.00 95.90  ?  120 ASP D N     1 
ATOM 4939 C CA    . ASP C 1 120 ? 169.712 155.127 114.213 1.00 95.90  ?  120 ASP D CA    1 
ATOM 4940 C C     . ASP C 1 120 ? 170.082 153.734 114.705 1.00 95.90  ?  120 ASP D C     1 
ATOM 4941 O O     . ASP C 1 120 ? 169.957 153.440 115.899 1.00 95.90  ?  120 ASP D O     1 
ATOM 4942 C CB    . ASP C 1 120 ? 170.671 156.175 114.776 1.00 95.90  ?  120 ASP D CB    1 
ATOM 4943 C CG    . ASP C 1 120 ? 171.930 156.319 113.944 1.00 95.90  ?  120 ASP D CG    1 
ATOM 4944 O OD1   . ASP C 1 120 ? 172.075 155.574 112.952 1.00 95.90  ?  120 ASP D OD1   1 
ATOM 4945 O OD2   . ASP C 1 120 ? 172.772 157.177 114.280 1.00 95.90  -1 120 ASP D OD2   1 
ATOM 4946 N N     . LEU C 1 121 ? 170.531 152.882 113.789 1.00 101.87 ?  121 LEU D N     1 
ATOM 4947 C CA    . LEU C 1 121 ? 170.855 151.500 114.101 1.00 101.87 ?  121 LEU D CA    1 
ATOM 4948 C C     . LEU C 1 121 ? 172.253 151.174 113.598 1.00 101.87 ?  121 LEU D C     1 
ATOM 4949 O O     . LEU C 1 121 ? 172.761 151.807 112.669 1.00 101.87 ?  121 LEU D O     1 
ATOM 4950 C CB    . LEU C 1 121 ? 169.841 150.530 113.478 1.00 101.87 ?  121 LEU D CB    1 
ATOM 4951 C CG    . LEU C 1 121 ? 168.507 150.376 114.207 1.00 101.87 ?  121 LEU D CG    1 
ATOM 4952 C CD1   . LEU C 1 121 ? 167.459 149.783 113.281 1.00 101.87 ?  121 LEU D CD1   1 
ATOM 4953 C CD2   . LEU C 1 121 ? 168.672 149.518 115.451 1.00 101.87 ?  121 LEU D CD2   1 
ATOM 4954 N N     . ASP C 1 122 ? 172.871 150.178 114.228 1.00 113.71 ?  122 ASP D N     1 
ATOM 4955 C CA    . ASP C 1 122 ? 174.181 149.697 113.807 1.00 113.71 ?  122 ASP D CA    1 
ATOM 4956 C C     . ASP C 1 122 ? 173.996 148.787 112.599 1.00 113.71 ?  122 ASP D C     1 
ATOM 4957 O O     . ASP C 1 122 ? 173.447 147.687 112.717 1.00 113.71 ?  122 ASP D O     1 
ATOM 4958 C CB    . ASP C 1 122 ? 174.878 148.965 114.950 1.00 113.71 ?  122 ASP D CB    1 
ATOM 4959 C CG    . ASP C 1 122 ? 176.350 148.721 114.676 1.00 113.71 ?  122 ASP D CG    1 
ATOM 4960 O OD1   . ASP C 1 122 ? 176.667 147.986 113.717 1.00 113.71 ?  122 ASP D OD1   1 
ATOM 4961 O OD2   . ASP C 1 122 ? 177.191 149.266 115.420 1.00 113.71 -1 122 ASP D OD2   1 
ATOM 4962 N N     . VAL C 1 123 ? 174.457 149.244 111.436 1.00 109.48 ?  123 VAL D N     1 
ATOM 4963 C CA    . VAL C 1 123 ? 174.282 148.498 110.196 1.00 109.48 ?  123 VAL D CA    1 
ATOM 4964 C C     . VAL C 1 123 ? 175.314 147.382 110.134 1.00 109.48 ?  123 VAL D C     1 
ATOM 4965 O O     . VAL C 1 123 ? 176.452 147.594 109.700 1.00 109.48 ?  123 VAL D O     1 
ATOM 4966 C CB    . VAL C 1 123 ? 174.391 149.423 108.970 1.00 109.48 ?  123 VAL D CB    1 
ATOM 4967 C CG1   . VAL C 1 123 ? 173.758 148.769 107.753 1.00 109.48 ?  123 VAL D CG1   1 
ATOM 4968 C CG2   . VAL C 1 123 ? 173.739 150.767 109.258 1.00 109.48 ?  123 VAL D CG2   1 
ATOM 4969 N N     . GLU C 1 124 ? 174.923 146.186 110.569 1.00 121.84 ?  124 GLU D N     1 
ATOM 4970 C CA    . GLU C 1 124 ? 175.796 145.015 110.530 1.00 121.84 ?  124 GLU D CA    1 
ATOM 4971 C C     . GLU C 1 124 ? 175.570 144.309 109.200 1.00 121.84 ?  124 GLU D C     1 
ATOM 4972 O O     . GLU C 1 124 ? 174.599 143.566 109.033 1.00 121.84 ?  124 GLU D O     1 
ATOM 4973 C CB    . GLU C 1 124 ? 175.513 144.092 111.710 1.00 121.84 ?  124 GLU D CB    1 
ATOM 4974 C CG    . GLU C 1 124 ? 175.988 144.632 113.047 1.00 121.84 ?  124 GLU D CG    1 
ATOM 4975 C CD    . GLU C 1 124 ? 175.561 143.758 114.209 1.00 121.84 ?  124 GLU D CD    1 
ATOM 4976 O OE1   . GLU C 1 124 ? 174.942 142.702 113.964 1.00 121.84 ?  124 GLU D OE1   1 
ATOM 4977 O OE2   . GLU C 1 124 ? 175.843 144.128 115.368 1.00 121.84 -1 124 GLU D OE2   1 
ATOM 4978 N N     . GLN C 1 125 ? 176.469 144.539 108.249 1.00 120.44 ?  125 GLN D N     1 
ATOM 4979 C CA    . GLN C 1 125 ? 176.342 143.979 106.910 1.00 120.44 ?  125 GLN D CA    1 
ATOM 4980 C C     . GLN C 1 125 ? 176.975 142.593 106.890 1.00 120.44 ?  125 GLN D C     1 
ATOM 4981 O O     . GLN C 1 125 ? 178.145 142.433 107.253 1.00 120.44 ?  125 GLN D O     1 
ATOM 4982 C CB    . GLN C 1 125 ? 176.999 144.900 105.881 1.00 120.44 ?  125 GLN D CB    1 
ATOM 4983 C CG    . GLN C 1 125 ? 176.631 144.622 104.423 1.00 120.44 ?  125 GLN D CG    1 
ATOM 4984 C CD    . GLN C 1 125 ? 177.222 143.332 103.888 1.00 120.44 ?  125 GLN D CD    1 
ATOM 4985 O OE1   . GLN C 1 125 ? 178.379 143.007 104.156 1.00 120.44 ?  125 GLN D OE1   1 
ATOM 4986 N NE2   . GLN C 1 125 ? 176.428 142.588 103.127 1.00 120.44 ?  125 GLN D NE2   1 
ATOM 4987 N N     . LEU C 1 126 ? 176.201 141.598 106.467 1.00 117.10 ?  126 LEU D N     1 
ATOM 4988 C CA    . LEU C 1 126 ? 176.677 140.230 106.317 1.00 117.10 ?  126 LEU D CA    1 
ATOM 4989 C C     . LEU C 1 126 ? 176.706 139.893 104.833 1.00 117.10 ?  126 LEU D C     1 
ATOM 4990 O O     . LEU C 1 126 ? 175.683 140.003 104.149 1.00 117.10 ?  126 LEU D O     1 
ATOM 4991 C CB    . LEU C 1 126 ? 175.789 139.243 107.077 1.00 117.10 ?  126 LEU D CB    1 
ATOM 4992 C CG    . LEU C 1 126 ? 175.272 139.635 108.464 1.00 117.10 ?  126 LEU D CG    1 
ATOM 4993 C CD1   . LEU C 1 126 ? 173.943 140.375 108.380 1.00 117.10 ?  126 LEU D CD1   1 
ATOM 4994 C CD2   . LEU C 1 126 ? 175.147 138.404 109.349 1.00 117.10 ?  126 LEU D CD2   1 
ATOM 4995 N N     . GLY C 1 127 ? 177.872 139.485 104.341 1.00 113.05 ?  127 GLY D N     1 
ATOM 4996 C CA    . GLY C 1 127 ? 178.013 139.158 102.937 1.00 113.05 ?  127 GLY D CA    1 
ATOM 4997 C C     . GLY C 1 127 ? 177.677 137.714 102.632 1.00 113.05 ?  127 GLY D C     1 
ATOM 4998 O O     . GLY C 1 127 ? 178.506 136.821 102.829 1.00 113.05 ?  127 GLY D O     1 
ATOM 4999 N N     . ILE C 1 128 ? 176.462 137.474 102.155 1.00 104.93 ?  128 ILE D N     1 
ATOM 5000 C CA    . ILE C 1 128 ? 176.054 136.107 101.813 1.00 104.93 ?  128 ILE D CA    1 
ATOM 5001 C C     . ILE C 1 128 ? 176.824 135.648 100.581 1.00 104.93 ?  128 ILE D C     1 
ATOM 5002 O O     . ILE C 1 128 ? 177.093 136.465 99.682  1.00 104.93 ?  128 ILE D O     1 
ATOM 5003 C CB    . ILE C 1 128 ? 174.543 136.045 101.580 1.00 104.93 ?  128 ILE D CB    1 
ATOM 5004 C CG1   . ILE C 1 128 ? 174.125 137.022 100.479 1.00 104.93 ?  128 ILE D CG1   1 
ATOM 5005 C CG2   . ILE C 1 128 ? 173.798 136.349 102.870 1.00 104.93 ?  128 ILE D CG2   1 
ATOM 5006 C CD1   . ILE C 1 128 ? 172.630 137.105 100.269 1.00 104.93 ?  128 ILE D CD1   1 
ATOM 5007 N N     . PRO C 1 129 ? 177.211 134.380 100.495 1.00 109.74 ?  129 PRO D N     1 
ATOM 5008 C CA    . PRO C 1 129 ? 177.942 133.899 99.322  1.00 109.74 ?  129 PRO D CA    1 
ATOM 5009 C C     . PRO C 1 129 ? 177.011 133.347 98.251  1.00 109.74 ?  129 PRO D C     1 
ATOM 5010 O O     . PRO C 1 129 ? 175.840 133.047 98.491  1.00 109.74 ?  129 PRO D O     1 
ATOM 5011 C CB    . PRO C 1 129 ? 178.832 132.788 99.899  1.00 109.74 ?  129 PRO D CB    1 
ATOM 5012 C CG    . PRO C 1 129 ? 178.149 132.353 101.183 1.00 109.74 ?  129 PRO D CG    1 
ATOM 5013 C CD    . PRO C 1 129 ? 177.042 133.326 101.507 1.00 109.74 ?  129 PRO D CD    1 
ATOM 5014 N N     . GLU C 1 130 ? 177.564 133.222 97.048  1.00 112.33 ?  130 GLU D N     1 
ATOM 5015 C CA    . GLU C 1 130 ? 176.843 132.687 95.898  1.00 112.33 ?  130 GLU D CA    1 
ATOM 5016 C C     . GLU C 1 130 ? 177.350 131.276 95.630  1.00 112.33 ?  130 GLU D C     1 
ATOM 5017 O O     . GLU C 1 130 ? 178.493 131.090 95.201  1.00 112.33 ?  130 GLU D O     1 
ATOM 5018 C CB    . GLU C 1 130 ? 177.027 133.581 94.673  1.00 112.33 ?  130 GLU D CB    1 
ATOM 5019 C CG    . GLU C 1 130 ? 176.471 134.987 94.834  1.00 112.33 ?  130 GLU D CG    1 
ATOM 5020 C CD    . GLU C 1 130 ? 177.415 135.907 95.584  1.00 112.33 ?  130 GLU D CD    1 
ATOM 5021 O OE1   . GLU C 1 130 ? 178.617 135.581 95.674  1.00 112.33 ?  130 GLU D OE1   1 
ATOM 5022 O OE2   . GLU C 1 130 ? 176.954 136.955 96.083  1.00 112.33 -1 130 GLU D OE2   1 
ATOM 5023 N N     . GLN C 1 131 ? 176.500 130.283 95.883  1.00 92.10  ?  131 GLN D N     1 
ATOM 5024 C CA    . GLN C 1 131 ? 176.859 128.885 95.711  1.00 92.10  ?  131 GLN D CA    1 
ATOM 5025 C C     . GLN C 1 131 ? 175.798 128.179 94.883  1.00 92.10  ?  131 GLN D C     1 
ATOM 5026 O O     . GLN C 1 131 ? 174.638 128.598 94.841  1.00 92.10  ?  131 GLN D O     1 
ATOM 5027 C CB    . GLN C 1 131 ? 177.011 128.167 97.059  1.00 92.10  ?  131 GLN D CB    1 
ATOM 5028 C CG    . GLN C 1 131 ? 177.282 129.086 98.235  1.00 92.10  ?  131 GLN D CG    1 
ATOM 5029 C CD    . GLN C 1 131 ? 177.249 128.354 99.560  1.00 92.10  ?  131 GLN D CD    1 
ATOM 5030 O OE1   . GLN C 1 131 ? 177.215 128.973 100.623 1.00 92.10  ?  131 GLN D OE1   1 
ATOM 5031 N NE2   . GLN C 1 131 ? 177.261 127.027 99.504  1.00 92.10  ?  131 GLN D NE2   1 
ATOM 5032 N N     . GLU C 1 132 ? 176.210 127.103 94.220  1.00 78.17  ?  132 GLU D N     1 
ATOM 5033 C CA    . GLU C 1 132 ? 175.269 126.242 93.526  1.00 78.17  ?  132 GLU D CA    1 
ATOM 5034 C C     . GLU C 1 132 ? 174.563 125.328 94.527  1.00 78.17  ?  132 GLU D C     1 
ATOM 5035 O O     . GLU C 1 132 ? 174.963 125.203 95.687  1.00 78.17  ?  132 GLU D O     1 
ATOM 5036 C CB    . GLU C 1 132 ? 175.983 125.422 92.453  1.00 78.17  ?  132 GLU D CB    1 
ATOM 5037 C CG    . GLU C 1 132 ? 176.577 124.117 92.956  1.00 78.17  ?  132 GLU D CG    1 
ATOM 5038 C CD    . GLU C 1 132 ? 177.668 124.330 93.986  1.00 78.17  ?  132 GLU D CD    1 
ATOM 5039 O OE1   . GLU C 1 132 ? 178.375 125.356 93.902  1.00 78.17  ?  132 GLU D OE1   1 
ATOM 5040 O OE2   . GLU C 1 132 ? 177.816 123.473 94.881  1.00 78.17  -1 132 GLU D OE2   1 
ATOM 5041 N N     . TYR C 1 133 ? 173.496 124.684 94.066  1.00 60.35  ?  133 TYR D N     1 
ATOM 5042 C CA    . TYR C 1 133 ? 172.681 123.838 94.923  1.00 60.35  ?  133 TYR D CA    1 
ATOM 5043 C C     . TYR C 1 133 ? 172.416 122.506 94.239  1.00 60.35  ?  133 TYR D C     1 
ATOM 5044 O O     . TYR C 1 133 ? 172.404 122.411 93.009  1.00 60.35  ?  133 TYR D O     1 
ATOM 5045 C CB    . TYR C 1 133 ? 171.362 124.527 95.281  1.00 60.35  ?  133 TYR D CB    1 
ATOM 5046 C CG    . TYR C 1 133 ? 171.552 125.787 96.091  1.00 60.35  ?  133 TYR D CG    1 
ATOM 5047 C CD1   . TYR C 1 133 ? 171.663 125.736 97.472  1.00 60.35  ?  133 TYR D CD1   1 
ATOM 5048 C CD2   . TYR C 1 133 ? 171.630 127.027 95.474  1.00 60.35  ?  133 TYR D CD2   1 
ATOM 5049 C CE1   . TYR C 1 133 ? 171.840 126.883 98.218  1.00 60.35  ?  133 TYR D CE1   1 
ATOM 5050 C CE2   . TYR C 1 133 ? 171.807 128.181 96.212  1.00 60.35  ?  133 TYR D CE2   1 
ATOM 5051 C CZ    . TYR C 1 133 ? 171.912 128.102 97.583  1.00 60.35  ?  133 TYR D CZ    1 
ATOM 5052 O OH    . TYR C 1 133 ? 172.088 129.246 98.325  1.00 60.35  ?  133 TYR D OH    1 
ATOM 5053 N N     . SER C 1 134 ? 172.204 121.473 95.055  1.00 54.83  ?  134 SER D N     1 
ATOM 5054 C CA    . SER C 1 134 ? 172.015 120.127 94.526  1.00 54.83  ?  134 SER D CA    1 
ATOM 5055 C C     . SER C 1 134 ? 170.581 119.908 94.058  1.00 54.83  ?  134 SER D C     1 
ATOM 5056 O O     . SER C 1 134 ? 170.334 119.665 92.872  1.00 54.83  ?  134 SER D O     1 
ATOM 5057 C CB    . SER C 1 134 ? 172.401 119.093 95.586  1.00 54.83  ?  134 SER D CB    1 
ATOM 5058 O OG    . SER C 1 134 ? 173.654 119.406 96.167  1.00 54.83  ?  134 SER D OG    1 
ATOM 5059 N N     . CYS C 1 135 ? 169.623 119.991 94.975  1.00 45.42  ?  135 CYS D N     1 
ATOM 5060 C CA    . CYS C 1 135 ? 168.214 119.793 94.660  1.00 45.42  ?  135 CYS D CA    1 
ATOM 5061 C C     . CYS C 1 135 ? 167.535 121.153 94.605  1.00 45.42  ?  135 CYS D C     1 
ATOM 5062 O O     . CYS C 1 135 ? 167.571 121.907 95.583  1.00 45.42  ?  135 CYS D O     1 
ATOM 5063 C CB    . CYS C 1 135 ? 167.538 118.890 95.694  1.00 45.42  ?  135 CYS D CB    1 
ATOM 5064 S SG    . CYS C 1 135 ? 165.802 118.504 95.338  1.00 45.42  ?  135 CYS D SG    1 
ATOM 5065 N N     . VAL C 1 136 ? 166.926 121.465 93.465  1.00 34.76  ?  136 VAL D N     1 
ATOM 5066 C CA    . VAL C 1 136 ? 166.190 122.707 93.270  1.00 34.76  ?  136 VAL D CA    1 
ATOM 5067 C C     . VAL C 1 136 ? 164.767 122.357 92.866  1.00 34.76  ?  136 VAL D C     1 
ATOM 5068 O O     . VAL C 1 136 ? 164.556 121.600 91.912  1.00 34.76  ?  136 VAL D O     1 
ATOM 5069 C CB    . VAL C 1 136 ? 166.858 123.607 92.216  1.00 34.76  ?  136 VAL D CB    1 
ATOM 5070 C CG1   . VAL C 1 136 ? 167.980 124.404 92.847  1.00 34.76  ?  136 VAL D CG1   1 
ATOM 5071 C CG2   . VAL C 1 136 ? 167.391 122.770 91.071  1.00 34.76  ?  136 VAL D CG2   1 
ATOM 5072 N N     . VAL C 1 137 ? 163.796 122.903 93.590  1.00 30.94  ?  137 VAL D N     1 
ATOM 5073 C CA    . VAL C 1 137 ? 162.389 122.587 93.388  1.00 30.94  ?  137 VAL D CA    1 
ATOM 5074 C C     . VAL C 1 137 ? 161.614 123.885 93.236  1.00 30.94  ?  137 VAL D C     1 
ATOM 5075 O O     . VAL C 1 137 ? 161.754 124.795 94.060  1.00 30.94  ?  137 VAL D O     1 
ATOM 5076 C CB    . VAL C 1 137 ? 161.822 121.759 94.556  1.00 30.94  ?  137 VAL D CB    1 
ATOM 5077 C CG1   . VAL C 1 137 ? 160.312 121.657 94.451  1.00 30.94  ?  137 VAL D CG1   1 
ATOM 5078 C CG2   . VAL C 1 137 ? 162.453 120.381 94.581  1.00 30.94  ?  137 VAL D CG2   1 
ATOM 5079 N N     . LYS C 1 138 ? 160.804 123.972 92.185  1.00 29.44  ?  138 LYS D N     1 
ATOM 5080 C CA    . LYS C 1 138 ? 159.869 125.073 91.999  1.00 29.44  ?  138 LYS D CA    1 
ATOM 5081 C C     . LYS C 1 138 ? 158.465 124.498 91.921  1.00 29.44  ?  138 LYS D C     1 
ATOM 5082 O O     . LYS C 1 138 ? 158.231 123.515 91.212  1.00 29.44  ?  138 LYS D O     1 
ATOM 5083 C CB    . LYS C 1 138 ? 160.196 125.882 90.742  1.00 29.44  ?  138 LYS D CB    1 
ATOM 5084 C CG    . LYS C 1 138 ? 160.291 125.066 89.468  1.00 29.44  ?  138 LYS D CG    1 
ATOM 5085 C CD    . LYS C 1 138 ? 160.653 125.942 88.278  1.00 29.44  ?  138 LYS D CD    1 
ATOM 5086 C CE    . LYS C 1 138 ? 159.894 127.260 88.302  1.00 29.44  ?  138 LYS D CE    1 
ATOM 5087 N NZ    . LYS C 1 138 ? 158.429 127.065 88.120  1.00 29.44  1  138 LYS D NZ    1 
ATOM 5088 N N     . MET C 1 139 ? 157.538 125.099 92.657  1.00 32.03  ?  139 MET D N     1 
ATOM 5089 C CA    . MET C 1 139 ? 156.203 124.541 92.807  1.00 32.03  ?  139 MET D CA    1 
ATOM 5090 C C     . MET C 1 139 ? 155.280 125.638 93.316  1.00 32.03  ?  139 MET D C     1 
ATOM 5091 O O     . MET C 1 139 ? 155.753 126.648 93.849  1.00 32.03  ?  139 MET D O     1 
ATOM 5092 C CB    . MET C 1 139 ? 156.219 123.335 93.759  1.00 32.03  ?  139 MET D CB    1 
ATOM 5093 C CG    . MET C 1 139 ? 157.095 123.518 94.981  1.00 32.03  ?  139 MET D CG    1 
ATOM 5094 S SD    . MET C 1 139 ? 156.564 122.470 96.342  1.00 32.03  ?  139 MET D SD    1 
ATOM 5095 C CE    . MET C 1 139 ? 155.242 123.459 97.013  1.00 32.03  ?  139 MET D CE    1 
ATOM 5096 N N     . PRO C 1 140 ? 153.965 125.484 93.148  1.00 35.23  ?  140 PRO D N     1 
ATOM 5097 C CA    . PRO C 1 140 ? 153.041 126.556 93.538  1.00 35.23  ?  140 PRO D CA    1 
ATOM 5098 C C     . PRO C 1 140 ? 153.153 126.906 95.015  1.00 35.23  ?  140 PRO D C     1 
ATOM 5099 O O     . PRO C 1 140 ? 153.367 126.040 95.865  1.00 35.23  ?  140 PRO D O     1 
ATOM 5100 C CB    . PRO C 1 140 ? 151.663 125.975 93.207  1.00 35.23  ?  140 PRO D CB    1 
ATOM 5101 C CG    . PRO C 1 140 ? 151.923 124.975 92.151  1.00 35.23  ?  140 PRO D CG    1 
ATOM 5102 C CD    . PRO C 1 140 ? 153.273 124.396 92.434  1.00 35.23  ?  140 PRO D CD    1 
ATOM 5103 N N     . SER C 1 141 ? 153.007 128.199 95.310  1.00 32.99  ?  141 SER D N     1 
ATOM 5104 C CA    . SER C 1 141 ? 153.123 128.667 96.687  1.00 32.99  ?  141 SER D CA    1 
ATOM 5105 C C     . SER C 1 141 ? 151.984 128.145 97.552  1.00 32.99  ?  141 SER D C     1 
ATOM 5106 O O     . SER C 1 141 ? 152.186 127.839 98.734  1.00 32.99  ?  141 SER D O     1 
ATOM 5107 C CB    . SER C 1 141 ? 153.157 130.193 96.721  1.00 32.99  ?  141 SER D CB    1 
ATOM 5108 O OG    . SER C 1 141 ? 152.607 130.680 97.932  1.00 32.99  ?  141 SER D OG    1 
ATOM 5109 N N     . GLY C 1 142 ? 150.778 128.059 96.989  1.00 36.16  ?  142 GLY D N     1 
ATOM 5110 C CA    . GLY C 1 142 ? 149.648 127.566 97.759  1.00 36.16  ?  142 GLY D CA    1 
ATOM 5111 C C     . GLY C 1 142 ? 149.866 126.156 98.270  1.00 36.16  ?  142 GLY D C     1 
ATOM 5112 O O     . GLY C 1 142 ? 149.521 125.837 99.411  1.00 36.16  ?  142 GLY D O     1 
ATOM 5113 N N     . GLU C 1 143 ? 150.450 125.294 97.435  1.00 37.54  ?  143 GLU D N     1 
ATOM 5114 C CA    . GLU C 1 143 ? 150.747 123.933 97.865  1.00 37.54  ?  143 GLU D CA    1 
ATOM 5115 C C     . GLU C 1 143 ? 151.744 123.922 99.016  1.00 37.54  ?  143 GLU D C     1 
ATOM 5116 O O     . GLU C 1 143 ? 151.584 123.160 99.975  1.00 37.54  ?  143 GLU D O     1 
ATOM 5117 C CB    . GLU C 1 143 ? 151.276 123.115 96.689  1.00 37.54  ?  143 GLU D CB    1 
ATOM 5118 C CG    . GLU C 1 143 ? 150.206 122.714 95.695  1.00 37.54  ?  143 GLU D CG    1 
ATOM 5119 C CD    . GLU C 1 143 ? 149.047 121.995 96.353  1.00 37.54  ?  143 GLU D CD    1 
ATOM 5120 O OE1   . GLU C 1 143 ? 149.296 121.131 97.219  1.00 37.54  ?  143 GLU D OE1   1 
ATOM 5121 O OE2   . GLU C 1 143 ? 147.886 122.295 96.007  1.00 37.54  -1 143 GLU D OE2   1 
ATOM 5122 N N     . PHE C 1 144 ? 152.782 124.758 98.939  1.00 32.78  ?  144 PHE D N     1 
ATOM 5123 C CA    . PHE C 1 144 ? 153.761 124.817 100.018 1.00 32.78  ?  144 PHE D CA    1 
ATOM 5124 C C     . PHE C 1 144 ? 153.123 125.288 101.317 1.00 32.78  ?  144 PHE D C     1 
ATOM 5125 O O     . PHE C 1 144 ? 153.370 124.714 102.386 1.00 32.78  ?  144 PHE D O     1 
ATOM 5126 C CB    . PHE C 1 144 ? 154.913 125.739 99.629  1.00 32.78  ?  144 PHE D CB    1 
ATOM 5127 C CG    . PHE C 1 144 ? 156.092 125.654 100.548 1.00 32.78  ?  144 PHE D CG    1 
ATOM 5128 C CD1   . PHE C 1 144 ? 156.774 124.463 100.707 1.00 32.78  ?  144 PHE D CD1   1 
ATOM 5129 C CD2   . PHE C 1 144 ? 156.521 126.765 101.248 1.00 32.78  ?  144 PHE D CD2   1 
ATOM 5130 C CE1   . PHE C 1 144 ? 157.860 124.381 101.550 1.00 32.78  ?  144 PHE D CE1   1 
ATOM 5131 C CE2   . PHE C 1 144 ? 157.606 126.689 102.091 1.00 32.78  ?  144 PHE D CE2   1 
ATOM 5132 C CZ    . PHE C 1 144 ? 158.276 125.495 102.243 1.00 32.78  ?  144 PHE D CZ    1 
ATOM 5133 N N     . ALA C 1 145 ? 152.299 126.335 101.243 1.00 35.28  ?  145 ALA D N     1 
ATOM 5134 C CA    . ALA C 1 145 ? 151.643 126.835 102.444 1.00 35.28  ?  145 ALA D CA    1 
ATOM 5135 C C     . ALA C 1 145 ? 150.721 125.783 103.042 1.00 35.28  ?  145 ALA D C     1 
ATOM 5136 O O     . ALA C 1 145 ? 150.708 125.579 104.262 1.00 35.28  ?  145 ALA D O     1 
ATOM 5137 C CB    . ALA C 1 145 ? 150.868 128.112 102.128 1.00 35.28  ?  145 ALA D CB    1 
ATOM 5138 N N     . ARG C 1 146 ? 149.951 125.095 102.196 1.00 38.67  ?  146 ARG D N     1 
ATOM 5139 C CA    . ARG C 1 146 ? 149.052 124.061 102.693 1.00 38.67  ?  146 ARG D CA    1 
ATOM 5140 C C     . ARG C 1 146 ? 149.828 122.911 103.321 1.00 38.67  ?  146 ARG D C     1 
ATOM 5141 O O     . ARG C 1 146 ? 149.430 122.385 104.366 1.00 38.67  ?  146 ARG D O     1 
ATOM 5142 C CB    . ARG C 1 146 ? 148.159 123.555 101.563 1.00 38.67  ?  146 ARG D CB    1 
ATOM 5143 C CG    . ARG C 1 146 ? 147.256 122.403 101.959 1.00 38.67  ?  146 ARG D CG    1 
ATOM 5144 C CD    . ARG C 1 146 ? 146.085 122.269 101.002 1.00 38.67  ?  146 ARG D CD    1 
ATOM 5145 N NE    . ARG C 1 146 ? 145.550 123.567 100.611 1.00 38.67  ?  146 ARG D NE    1 
ATOM 5146 C CZ    . ARG C 1 146 ? 145.485 124.005 99.361  1.00 38.67  ?  146 ARG D CZ    1 
ATOM 5147 N NH1   . ARG C 1 146 ? 145.917 123.271 98.349  1.00 38.67  1  146 ARG D NH1   1 
ATOM 5148 N NH2   . ARG C 1 146 ? 144.974 125.209 99.121  1.00 38.67  ?  146 ARG D NH2   1 
ATOM 5149 N N     . ILE C 1 147 ? 150.941 122.510 102.704 1.00 33.26  ?  147 ILE D N     1 
ATOM 5150 C CA    . ILE C 1 147 ? 151.739 121.412 103.242 1.00 33.26  ?  147 ILE D CA    1 
ATOM 5151 C C     . ILE C 1 147 ? 152.296 121.782 104.610 1.00 33.26  ?  147 ILE D C     1 
ATOM 5152 O O     . ILE C 1 147 ? 152.228 120.995 105.562 1.00 33.26  ?  147 ILE D O     1 
ATOM 5153 C CB    . ILE C 1 147 ? 152.862 121.037 102.260 1.00 33.26  ?  147 ILE D CB    1 
ATOM 5154 C CG1   . ILE C 1 147 ? 152.306 120.192 101.117 1.00 33.26  ?  147 ILE D CG1   1 
ATOM 5155 C CG2   . ILE C 1 147 ? 153.969 120.289 102.975 1.00 33.26  ?  147 ILE D CG2   1 
ATOM 5156 C CD1   . ILE C 1 147 ? 153.314 119.910 100.033 1.00 33.26  ?  147 ILE D CD1   1 
ATOM 5157 N N     . CYS C 1 148 ? 152.857 122.987 104.728 1.00 34.73  ?  148 CYS D N     1 
ATOM 5158 C CA    . CYS C 1 148 ? 153.414 123.406 106.011 1.00 34.73  ?  148 CYS D CA    1 
ATOM 5159 C C     . CYS C 1 148 ? 152.330 123.505 107.077 1.00 34.73  ?  148 CYS D C     1 
ATOM 5160 O O     . CYS C 1 148 ? 152.523 123.054 108.214 1.00 34.73  ?  148 CYS D O     1 
ATOM 5161 C CB    . CYS C 1 148 ? 154.146 124.736 105.858 1.00 34.73  ?  148 CYS D CB    1 
ATOM 5162 S SG    . CYS C 1 148 ? 155.764 124.591 105.071 1.00 34.73  ?  148 CYS D SG    1 
ATOM 5163 N N     . ARG C 1 149 ? 151.175 124.076 106.727 1.00 36.66  ?  149 ARG D N     1 
ATOM 5164 C CA    . ARG C 1 149 ? 150.093 124.195 107.697 1.00 36.66  ?  149 ARG D CA    1 
ATOM 5165 C C     . ARG C 1 149 ? 149.595 122.826 108.140 1.00 36.66  ?  149 ARG D C     1 
ATOM 5166 O O     . ARG C 1 149 ? 149.319 122.613 109.326 1.00 36.66  ?  149 ARG D O     1 
ATOM 5167 C CB    . ARG C 1 149 ? 148.951 125.020 107.107 1.00 36.66  ?  149 ARG D CB    1 
ATOM 5168 C CG    . ARG C 1 149 ? 148.139 125.787 108.136 1.00 36.66  ?  149 ARG D CG    1 
ATOM 5169 C CD    . ARG C 1 149 ? 146.969 124.963 108.649 1.00 36.66  ?  149 ARG D CD    1 
ATOM 5170 N NE    . ARG C 1 149 ? 146.377 124.130 107.609 1.00 36.66  ?  149 ARG D NE    1 
ATOM 5171 C CZ    . ARG C 1 149 ? 145.584 124.580 106.645 1.00 36.66  ?  149 ARG D CZ    1 
ATOM 5172 N NH1   . ARG C 1 149 ? 145.265 125.860 106.552 1.00 36.66  1  149 ARG D NH1   1 
ATOM 5173 N NH2   . ARG C 1 149 ? 145.098 123.722 105.752 1.00 36.66  ?  149 ARG D NH2   1 
ATOM 5174 N N     . ASP C 1 150 ? 149.466 121.887 107.201 1.00 39.44  ?  150 ASP D N     1 
ATOM 5175 C CA    . ASP C 1 150 ? 149.014 120.546 107.552 1.00 39.44  ?  150 ASP D CA    1 
ATOM 5176 C C     . ASP C 1 150 ? 150.020 119.838 108.448 1.00 39.44  ?  150 ASP D C     1 
ATOM 5177 O O     . ASP C 1 150 ? 149.637 119.182 109.422 1.00 39.44  ?  150 ASP D O     1 
ATOM 5178 C CB    . ASP C 1 150 ? 148.761 119.730 106.286 1.00 39.44  ?  150 ASP D CB    1 
ATOM 5179 C CG    . ASP C 1 150 ? 147.546 120.208 105.519 1.00 39.44  ?  150 ASP D CG    1 
ATOM 5180 O OD1   . ASP C 1 150 ? 146.824 121.086 106.036 1.00 39.44  ?  150 ASP D OD1   1 
ATOM 5181 O OD2   . ASP C 1 150 ? 147.315 119.708 104.399 1.00 39.44  -1 150 ASP D OD2   1 
ATOM 5182 N N     . LEU C 1 151 ? 151.313 119.958 108.138 1.00 32.26  ?  151 LEU D N     1 
ATOM 5183 C CA    . LEU C 1 151 ? 152.317 119.273 108.943 1.00 32.26  ?  151 LEU D CA    1 
ATOM 5184 C C     . LEU C 1 151 ? 152.467 119.908 110.317 1.00 32.26  ?  151 LEU D C     1 
ATOM 5185 O O     . LEU C 1 151 ? 152.895 119.235 111.261 1.00 32.26  ?  151 LEU D O     1 
ATOM 5186 C CB    . LEU C 1 151 ? 153.657 119.258 108.214 1.00 32.26  ?  151 LEU D CB    1 
ATOM 5187 C CG    . LEU C 1 151 ? 153.732 118.302 107.025 1.00 32.26  ?  151 LEU D CG    1 
ATOM 5188 C CD1   . LEU C 1 151 ? 155.165 118.131 106.561 1.00 32.26  ?  151 LEU D CD1   1 
ATOM 5189 C CD2   . LEU C 1 151 ? 153.124 116.963 107.388 1.00 32.26  ?  151 LEU D CD2   1 
ATOM 5190 N N     . SER C 1 152 ? 152.122 121.190 110.457 1.00 36.72  ?  152 SER D N     1 
ATOM 5191 C CA    . SER C 1 152 ? 152.222 121.832 111.763 1.00 36.72  ?  152 SER D CA    1 
ATOM 5192 C C     . SER C 1 152 ? 151.273 121.224 112.787 1.00 36.72  ?  152 SER D C     1 
ATOM 5193 O O     . SER C 1 152 ? 151.462 121.433 113.989 1.00 36.72  ?  152 SER D O     1 
ATOM 5194 C CB    . SER C 1 152 ? 151.957 123.331 111.638 1.00 36.72  ?  152 SER D CB    1 
ATOM 5195 O OG    . SER C 1 152 ? 153.148 124.031 111.324 1.00 36.72  ?  152 SER D OG    1 
ATOM 5196 N N     . HIS C 1 153 ? 150.262 120.478 112.345 1.00 39.94  ?  153 HIS D N     1 
ATOM 5197 C CA    . HIS C 1 153 ? 149.320 119.855 113.266 1.00 39.94  ?  153 HIS D CA    1 
ATOM 5198 C C     . HIS C 1 153 ? 149.818 118.530 113.826 1.00 39.94  ?  153 HIS D C     1 
ATOM 5199 O O     . HIS C 1 153 ? 149.143 117.948 114.681 1.00 39.94  ?  153 HIS D O     1 
ATOM 5200 C CB    . HIS C 1 153 ? 147.973 119.633 112.573 1.00 39.94  ?  153 HIS D CB    1 
ATOM 5201 C CG    . HIS C 1 153 ? 147.279 120.899 112.181 1.00 39.94  ?  153 HIS D CG    1 
ATOM 5202 N ND1   . HIS C 1 153 ? 146.861 121.834 113.103 1.00 39.94  ?  153 HIS D ND1   1 
ATOM 5203 C CD2   . HIS C 1 153 ? 146.928 121.385 110.968 1.00 39.94  ?  153 HIS D CD2   1 
ATOM 5204 C CE1   . HIS C 1 153 ? 146.283 122.842 112.474 1.00 39.94  ?  153 HIS D CE1   1 
ATOM 5205 N NE2   . HIS C 1 153 ? 146.311 122.594 111.177 1.00 39.94  ?  153 HIS D NE2   1 
ATOM 5206 N N     . ILE C 1 154 ? 150.968 118.039 113.372 1.00 40.40  ?  154 ILE D N     1 
ATOM 5207 C CA    . ILE C 1 154 ? 151.486 116.733 113.774 1.00 40.40  ?  154 ILE D CA    1 
ATOM 5208 C C     . ILE C 1 154 ? 152.759 116.872 114.603 1.00 40.40  ?  154 ILE D C     1 
ATOM 5209 O O     . ILE C 1 154 ? 152.805 116.453 115.760 1.00 40.40  ?  154 ILE D O     1 
ATOM 5210 C CB    . ILE C 1 154 ? 151.713 115.825 112.545 1.00 40.40  ?  154 ILE D CB    1 
ATOM 5211 C CG1   . ILE C 1 154 ? 150.389 115.561 111.831 1.00 40.40  ?  154 ILE D CG1   1 
ATOM 5212 C CG2   . ILE C 1 154 ? 152.360 114.520 112.961 1.00 40.40  ?  154 ILE D CG2   1 
ATOM 5213 C CD1   . ILE C 1 154 ? 149.283 115.119 112.756 1.00 40.40  ?  154 ILE D CD1   1 
ATOM 5214 N N     . GLY C 1 155 ? 153.804 117.456 114.027 1.00 41.37  ?  155 GLY D N     1 
ATOM 5215 C CA    . GLY C 1 155 ? 155.060 117.599 114.734 1.00 41.37  ?  155 GLY D CA    1 
ATOM 5216 C C     . GLY C 1 155 ? 155.739 118.924 114.468 1.00 41.37  ?  155 GLY D C     1 
ATOM 5217 O O     . GLY C 1 155 ? 155.111 119.857 113.962 1.00 41.37  ?  155 GLY D O     1 
ATOM 5218 N N     . ASP C 1 156 ? 157.021 119.020 114.809 1.00 44.32  ?  156 ASP D N     1 
ATOM 5219 C CA    . ASP C 1 156 ? 157.817 120.220 114.585 1.00 44.32  ?  156 ASP D CA    1 
ATOM 5220 C C     . ASP C 1 156 ? 159.156 119.864 113.961 1.00 44.32  ?  156 ASP D C     1 
ATOM 5221 O O     . ASP C 1 156 ? 160.193 120.442 114.296 1.00 44.32  ?  156 ASP D O     1 
ATOM 5222 C CB    . ASP C 1 156 ? 158.023 120.994 115.884 1.00 44.32  ?  156 ASP D CB    1 
ATOM 5223 C CG    . ASP C 1 156 ? 156.964 122.053 116.106 1.00 44.32  ?  156 ASP D CG    1 
ATOM 5224 O OD1   . ASP C 1 156 ? 155.774 121.768 115.861 1.00 44.32  ?  156 ASP D OD1   1 
ATOM 5225 O OD2   . ASP C 1 156 ? 157.323 123.174 116.521 1.00 44.32  -1 156 ASP D OD2   1 
ATOM 5226 N N     . ALA C 1 157 ? 159.157 118.900 113.040 1.00 36.25  ?  157 ALA D N     1 
ATOM 5227 C CA    . ALA C 1 157 ? 160.396 118.464 112.400 1.00 36.25  ?  157 ALA D CA    1 
ATOM 5228 C C     . ALA C 1 157 ? 160.047 117.938 111.011 1.00 36.25  ?  157 ALA D C     1 
ATOM 5229 O O     . ALA C 1 157 ? 159.579 116.805 110.875 1.00 36.25  ?  157 ALA D O     1 
ATOM 5230 C CB    . ALA C 1 157 ? 161.102 117.407 113.237 1.00 36.25  ?  157 ALA D CB    1 
ATOM 5231 N N     . VAL C 1 158 ? 160.278 118.760 109.996 1.00 29.68  ?  158 VAL D N     1 
ATOM 5232 C CA    . VAL C 1 158 ? 160.074 118.363 108.609 1.00 29.68  ?  158 VAL D CA    1 
ATOM 5233 C C     . VAL C 1 158 ? 161.370 117.772 108.077 1.00 29.68  ?  158 VAL D C     1 
ATOM 5234 O O     . VAL C 1 158 ? 162.445 118.357 108.247 1.00 29.68  ?  158 VAL D O     1 
ATOM 5235 C CB    . VAL C 1 158 ? 159.622 119.557 107.756 1.00 29.68  ?  158 VAL D CB    1 
ATOM 5236 C CG1   . VAL C 1 158 ? 159.704 119.214 106.287 1.00 29.68  ?  158 VAL D CG1   1 
ATOM 5237 C CG2   . VAL C 1 158 ? 158.212 119.941 108.114 1.00 29.68  ?  158 VAL D CG2   1 
ATOM 5238 N N     . VAL C 1 159 ? 161.273 116.615 107.438 1.00 29.14  ?  159 VAL D N     1 
ATOM 5239 C CA    . VAL C 1 159 ? 162.427 115.942 106.850 1.00 29.14  ?  159 VAL D CA    1 
ATOM 5240 C C     . VAL C 1 159 ? 162.190 115.910 105.346 1.00 29.14  ?  159 VAL D C     1 
ATOM 5241 O O     . VAL C 1 159 ? 161.556 114.996 104.813 1.00 29.14  ?  159 VAL D O     1 
ATOM 5242 C CB    . VAL C 1 159 ? 162.636 114.537 107.418 1.00 29.14  ?  159 VAL D CB    1 
ATOM 5243 C CG1   . VAL C 1 159 ? 163.853 113.887 106.785 1.00 29.14  ?  159 VAL D CG1   1 
ATOM 5244 C CG2   . VAL C 1 159 ? 162.786 114.597 108.927 1.00 29.14  ?  159 VAL D CG2   1 
ATOM 5245 N N     . ILE C 1 160 ? 162.703 116.913 104.647 1.00 29.14  ?  160 ILE D N     1 
ATOM 5246 C CA    . ILE C 1 160 ? 162.566 116.983 103.199 1.00 29.14  ?  160 ILE D CA    1 
ATOM 5247 C C     . ILE C 1 160 ? 163.552 116.020 102.558 1.00 29.14  ?  160 ILE D C     1 
ATOM 5248 O O     . ILE C 1 160 ? 164.680 115.852 103.033 1.00 29.14  ?  160 ILE D O     1 
ATOM 5249 C CB    . ILE C 1 160 ? 162.787 118.421 102.702 1.00 29.14  ?  160 ILE D CB    1 
ATOM 5250 C CG1   . ILE C 1 160 ? 162.016 119.406 103.577 1.00 29.14  ?  160 ILE D CG1   1 
ATOM 5251 C CG2   . ILE C 1 160 ? 162.362 118.555 101.251 1.00 29.14  ?  160 ILE D CG2   1 
ATOM 5252 C CD1   . ILE C 1 160 ? 161.936 120.798 103.005 1.00 29.14  ?  160 ILE D CD1   1 
ATOM 5253 N N     . SER C 1 161 ? 163.124 115.379 101.475 1.00 38.81  ?  161 SER D N     1 
ATOM 5254 C CA    . SER C 1 161 ? 163.986 114.465 100.732 1.00 38.81  ?  161 SER D CA    1 
ATOM 5255 C C     . SER C 1 161 ? 163.452 114.389 99.312  1.00 38.81  ?  161 SER D C     1 
ATOM 5256 O O     . SER C 1 161 ? 162.357 113.865 99.090  1.00 38.81  ?  161 SER D O     1 
ATOM 5257 C CB    . SER C 1 161 ? 164.021 113.086 101.381 1.00 38.81  ?  161 SER D CB    1 
ATOM 5258 O OG    . SER C 1 161 ? 164.740 113.115 102.601 1.00 38.81  ?  161 SER D OG    1 
ATOM 5259 N N     . CYS C 1 162 ? 164.217 114.909 98.357  1.00 50.20  ?  162 CYS D N     1 
ATOM 5260 C CA    . CYS C 1 162 ? 163.792 114.896 96.963  1.00 50.20  ?  162 CYS D CA    1 
ATOM 5261 C C     . CYS C 1 162 ? 163.791 113.456 96.467  1.00 50.20  ?  162 CYS D C     1 
ATOM 5262 O O     . CYS C 1 162 ? 164.847 112.898 96.152  1.00 50.20  ?  162 CYS D O     1 
ATOM 5263 C CB    . CYS C 1 162 ? 164.715 115.770 96.121  1.00 50.20  ?  162 CYS D CB    1 
ATOM 5264 S SG    . CYS C 1 162 ? 165.195 117.336 96.887  1.00 50.20  ?  162 CYS D SG    1 
ATOM 5265 N N     . ALA C 1 163 ? 162.609 112.854 96.395  1.00 62.09  ?  163 ALA D N     1 
ATOM 5266 C CA    . ALA C 1 163 ? 162.477 111.446 96.059  1.00 62.09  ?  163 ALA D CA    1 
ATOM 5267 C C     . ALA C 1 163 ? 162.538 111.264 94.544  1.00 62.09  ?  163 ALA D C     1 
ATOM 5268 O O     . ALA C 1 163 ? 162.900 112.177 93.798  1.00 62.09  ?  163 ALA D O     1 
ATOM 5269 C CB    . ALA C 1 163 ? 161.187 110.881 96.650  1.00 62.09  ?  163 ALA D CB    1 
ATOM 5270 N N     . LYS C 1 164 ? 162.188 110.063 94.079  1.00 81.22  ?  164 LYS D N     1 
ATOM 5271 C CA    . LYS C 1 164 ? 162.297 109.749 92.658  1.00 81.22  ?  164 LYS D CA    1 
ATOM 5272 C C     . LYS C 1 164 ? 161.384 110.631 91.815  1.00 81.22  ?  164 LYS D C     1 
ATOM 5273 O O     . LYS C 1 164 ? 161.797 111.135 90.763  1.00 81.22  ?  164 LYS D O     1 
ATOM 5274 C CB    . LYS C 1 164 ? 161.978 108.270 92.431  1.00 81.22  ?  164 LYS D CB    1 
ATOM 5275 C CG    . LYS C 1 164 ? 161.758 107.881 90.978  1.00 81.22  ?  164 LYS D CG    1 
ATOM 5276 C CD    . LYS C 1 164 ? 162.987 108.161 90.129  1.00 81.22  ?  164 LYS D CD    1 
ATOM 5277 C CE    . LYS C 1 164 ? 162.594 108.609 88.731  1.00 81.22  ?  164 LYS D CE    1 
ATOM 5278 N NZ    . LYS C 1 164 ? 161.906 109.929 88.743  1.00 81.22  1  164 LYS D NZ    1 
ATOM 5279 N N     . ASP C 1 165 ? 160.145 110.839 92.258  1.00 70.60  ?  165 ASP D N     1 
ATOM 5280 C CA    . ASP C 1 165 ? 159.154 111.559 91.468  1.00 70.60  ?  165 ASP D CA    1 
ATOM 5281 C C     . ASP C 1 165 ? 158.585 112.762 92.215  1.00 70.60  ?  165 ASP D C     1 
ATOM 5282 O O     . ASP C 1 165 ? 157.456 113.180 91.957  1.00 70.60  ?  165 ASP D O     1 
ATOM 5283 C CB    . ASP C 1 165 ? 158.030 110.621 91.033  1.00 70.60  ?  165 ASP D CB    1 
ATOM 5284 C CG    . ASP C 1 165 ? 157.297 110.009 92.208  1.00 70.60  ?  165 ASP D CG    1 
ATOM 5285 O OD1   . ASP C 1 165 ? 157.905 109.891 93.293  1.00 70.60  ?  165 ASP D OD1   1 
ATOM 5286 O OD2   . ASP C 1 165 ? 156.114 109.643 92.047  1.00 70.60  -1 165 ASP D OD2   1 
ATOM 5287 N N     . GLY C 1 166 ? 159.347 113.326 93.138  1.00 54.66  ?  166 GLY D N     1 
ATOM 5288 C CA    . GLY C 1 166 ? 158.923 114.532 93.816  1.00 54.66  ?  166 GLY D CA    1 
ATOM 5289 C C     . GLY C 1 166 ? 159.499 114.599 95.215  1.00 54.66  ?  166 GLY D C     1 
ATOM 5290 O O     . GLY C 1 166 ? 160.399 113.845 95.567  1.00 54.66  ?  166 GLY D O     1 
ATOM 5291 N N     . VAL C 1 167 ? 158.954 115.524 95.993  1.00 40.17  ?  167 VAL D N     1 
ATOM 5292 C CA    . VAL C 1 167 ? 159.410 115.761 97.352  1.00 40.17  ?  167 VAL D CA    1 
ATOM 5293 C C     . VAL C 1 167 ? 158.746 114.763 98.292  1.00 40.17  ?  167 VAL D C     1 
ATOM 5294 O O     . VAL C 1 167 ? 157.749 114.121 97.956  1.00 40.17  ?  167 VAL D O     1 
ATOM 5295 C CB    . VAL C 1 167 ? 159.123 117.209 97.783  1.00 40.17  ?  167 VAL D CB    1 
ATOM 5296 C CG1   . VAL C 1 167 ? 160.067 118.162 97.076  1.00 40.17  ?  167 VAL D CG1   1 
ATOM 5297 C CG2   . VAL C 1 167 ? 157.689 117.560 97.460  1.00 40.17  ?  167 VAL D CG2   1 
ATOM 5298 N N     . LYS C 1 168 ? 159.312 114.628 99.487  1.00 33.43  ?  168 LYS D N     1 
ATOM 5299 C CA    . LYS C 1 168 ? 158.861 113.639 100.460 1.00 33.43  ?  168 LYS D CA    1 
ATOM 5300 C C     . LYS C 1 168 ? 158.779 114.249 101.855 1.00 33.43  ?  168 LYS D C     1 
ATOM 5301 O O     . LYS C 1 168 ? 159.349 113.728 102.814 1.00 33.43  ?  168 LYS D O     1 
ATOM 5302 C CB    . LYS C 1 168 ? 159.773 112.415 100.456 1.00 33.43  ?  168 LYS D CB    1 
ATOM 5303 C CG    . LYS C 1 168 ? 159.148 111.184 99.826  1.00 33.43  ?  168 LYS D CG    1 
ATOM 5304 C CD    . LYS C 1 168 ? 159.945 109.930 100.144 1.00 33.43  ?  168 LYS D CD    1 
ATOM 5305 C CE    . LYS C 1 168 ? 160.219 109.811 101.635 1.00 33.43  ?  168 LYS D CE    1 
ATOM 5306 N NZ    . LYS C 1 168 ? 158.964 109.836 102.435 1.00 33.43  1  168 LYS D NZ    1 
ATOM 5307 N N     . PHE C 1 169 ? 158.098 115.391 101.974 1.00 24.09  ?  169 PHE D N     1 
ATOM 5308 C CA    . PHE C 1 169 ? 157.894 116.018 103.277 1.00 24.09  ?  169 PHE D CA    1 
ATOM 5309 C C     . PHE C 1 169 ? 157.412 114.996 104.296 1.00 24.09  ?  169 PHE D C     1 
ATOM 5310 O O     . PHE C 1 169 ? 156.427 114.292 104.068 1.00 24.09  ?  169 PHE D O     1 
ATOM 5311 C CB    . PHE C 1 169 ? 156.877 117.154 103.168 1.00 24.09  ?  169 PHE D CB    1 
ATOM 5312 C CG    . PHE C 1 169 ? 157.265 118.230 102.203 1.00 24.09  ?  169 PHE D CG    1 
ATOM 5313 C CD1   . PHE C 1 169 ? 158.367 119.028 102.441 1.00 24.09  ?  169 PHE D CD1   1 
ATOM 5314 C CD2   . PHE C 1 169 ? 156.513 118.461 101.068 1.00 24.09  ?  169 PHE D CD2   1 
ATOM 5315 C CE1   . PHE C 1 169 ? 158.721 120.024 101.557 1.00 24.09  ?  169 PHE D CE1   1 
ATOM 5316 C CE2   . PHE C 1 169 ? 156.860 119.457 100.184 1.00 24.09  ?  169 PHE D CE2   1 
ATOM 5317 C CZ    . PHE C 1 169 ? 157.966 120.238 100.428 1.00 24.09  ?  169 PHE D CZ    1 
ATOM 5318 N N     . SER C 1 170 ? 158.116 114.914 105.424 1.00 29.04  ?  170 SER D N     1 
ATOM 5319 C CA    . SER C 1 170 ? 157.847 113.889 106.430 1.00 29.04  ?  170 SER D CA    1 
ATOM 5320 C C     . SER C 1 170 ? 157.985 114.506 107.813 1.00 29.04  ?  170 SER D C     1 
ATOM 5321 O O     . SER C 1 170 ? 159.076 114.936 108.196 1.00 29.04  ?  170 SER D O     1 
ATOM 5322 C CB    . SER C 1 170 ? 158.797 112.703 106.273 1.00 29.04  ?  170 SER D CB    1 
ATOM 5323 O OG    . SER C 1 170 ? 158.952 112.351 104.911 1.00 29.04  ?  170 SER D OG    1 
ATOM 5324 N N     . ALA C 1 171 ? 156.888 114.547 108.558 1.00 28.61  ?  171 ALA D N     1 
ATOM 5325 C CA    . ALA C 1 171 ? 156.901 114.955 109.952 1.00 28.61  ?  171 ALA D CA    1 
ATOM 5326 C C     . ALA C 1 171 ? 156.805 113.729 110.849 1.00 28.61  ?  171 ALA D C     1 
ATOM 5327 O O     . ALA C 1 171 ? 156.459 112.633 110.405 1.00 28.61  ?  171 ALA D O     1 
ATOM 5328 C CB    . ALA C 1 171 ? 155.752 115.919 110.253 1.00 28.61  ?  171 ALA D CB    1 
ATOM 5329 N N     . SER C 1 172 ? 157.126 113.924 112.128 1.00 41.78  ?  172 SER D N     1 
ATOM 5330 C CA    . SER C 1 172 ? 157.052 112.832 113.098 1.00 41.78  ?  172 SER D CA    1 
ATOM 5331 C C     . SER C 1 172 ? 156.867 113.445 114.483 1.00 41.78  ?  172 SER D C     1 
ATOM 5332 O O     . SER C 1 172 ? 157.832 113.917 115.090 1.00 41.78  ?  172 SER D O     1 
ATOM 5333 C CB    . SER C 1 172 ? 158.296 111.957 113.038 1.00 41.78  ?  172 SER D CB    1 
ATOM 5334 O OG    . SER C 1 172 ? 158.377 111.117 114.176 1.00 41.78  ?  172 SER D OG    1 
ATOM 5335 N N     . GLY C 1 173 ? 155.628 113.429 114.973 1.00 51.70  ?  173 GLY D N     1 
ATOM 5336 C CA    . GLY C 1 173 ? 155.311 113.893 116.300 1.00 51.70  ?  173 GLY D CA    1 
ATOM 5337 C C     . GLY C 1 173 ? 154.892 112.762 117.221 1.00 51.70  ?  173 GLY D C     1 
ATOM 5338 O O     . GLY C 1 173 ? 155.024 111.577 116.907 1.00 51.70  ?  173 GLY D O     1 
ATOM 5339 N N     . GLU C 1 174 ? 154.379 113.153 118.388 1.00 64.11  ?  174 GLU D N     1 
ATOM 5340 C CA    . GLU C 1 174 ? 153.874 112.162 119.331 1.00 64.11  ?  174 GLU D CA    1 
ATOM 5341 C C     . GLU C 1 174 ? 152.581 111.529 118.836 1.00 64.11  ?  174 GLU D C     1 
ATOM 5342 O O     . GLU C 1 174 ? 152.310 110.360 119.132 1.00 64.11  ?  174 GLU D O     1 
ATOM 5343 C CB    . GLU C 1 174 ? 153.665 112.799 120.705 1.00 64.11  ?  174 GLU D CB    1 
ATOM 5344 C CG    . GLU C 1 174 ? 152.860 114.089 120.682 1.00 64.11  ?  174 GLU D CG    1 
ATOM 5345 C CD    . GLU C 1 174 ? 151.364 113.845 120.709 1.00 64.11  ?  174 GLU D CD    1 
ATOM 5346 O OE1   . GLU C 1 174 ? 150.930 112.888 121.382 1.00 64.11  ?  174 GLU D OE1   1 
ATOM 5347 O OE2   . GLU C 1 174 ? 150.624 114.605 120.050 1.00 64.11  -1 174 GLU D OE2   1 
ATOM 5348 N N     . LEU C 1 175 ? 151.771 112.284 118.091 1.00 55.31  ?  175 LEU D N     1 
ATOM 5349 C CA    . LEU C 1 175 ? 150.501 111.757 117.607 1.00 55.31  ?  175 LEU D CA    1 
ATOM 5350 C C     . LEU C 1 175 ? 150.711 110.716 116.516 1.00 55.31  ?  175 LEU D C     1 
ATOM 5351 O O     . LEU C 1 175 ? 150.012 109.697 116.478 1.00 55.31  ?  175 LEU D O     1 
ATOM 5352 C CB    . LEU C 1 175 ? 149.629 112.901 117.093 1.00 55.31  ?  175 LEU D CB    1 
ATOM 5353 C CG    . LEU C 1 175 ? 148.121 112.692 117.186 1.00 55.31  ?  175 LEU D CG    1 
ATOM 5354 C CD1   . LEU C 1 175 ? 147.779 111.926 118.454 1.00 55.31  ?  175 LEU D CD1   1 
ATOM 5355 C CD2   . LEU C 1 175 ? 147.403 114.030 117.148 1.00 55.31  ?  175 LEU D CD2   1 
ATOM 5356 N N     . GLY C 1 176 ? 151.668 110.953 115.626 1.00 44.98  ?  176 GLY D N     1 
ATOM 5357 C CA    . GLY C 1 176 ? 151.910 110.038 114.528 1.00 44.98  ?  176 GLY D CA    1 
ATOM 5358 C C     . GLY C 1 176 ? 152.926 110.630 113.573 1.00 44.98  ?  176 GLY D C     1 
ATOM 5359 O O     . GLY C 1 176 ? 153.596 111.612 113.894 1.00 44.98  ?  176 GLY D O     1 
ATOM 5360 N N     . ASN C 1 177 ? 153.031 110.016 112.400 1.00 35.88  ?  177 ASN D N     1 
ATOM 5361 C CA    . ASN C 1 177 ? 153.948 110.473 111.366 1.00 35.88  ?  177 ASN D CA    1 
ATOM 5362 C C     . ASN C 1 177 ? 153.196 110.588 110.051 1.00 35.88  ?  177 ASN D C     1 
ATOM 5363 O O     . ASN C 1 177 ? 152.512 109.646 109.641 1.00 35.88  ?  177 ASN D O     1 
ATOM 5364 C CB    . ASN C 1 177 ? 155.136 109.521 111.221 1.00 35.88  ?  177 ASN D CB    1 
ATOM 5365 C CG    . ASN C 1 177 ? 154.754 108.079 111.458 1.00 35.88  ?  177 ASN D CG    1 
ATOM 5366 O OD1   . ASN C 1 177 ? 154.504 107.670 112.592 1.00 35.88  ?  177 ASN D OD1   1 
ATOM 5367 N ND2   . ASN C 1 177 ? 154.704 107.296 110.388 1.00 35.88  ?  177 ASN D ND2   1 
ATOM 5368 N N     . GLY C 1 178 ? 153.328 111.736 109.394 1.00 26.78  ?  178 GLY D N     1 
ATOM 5369 C CA    . GLY C 1 178 ? 152.640 111.967 108.141 1.00 26.78  ?  178 GLY D CA    1 
ATOM 5370 C C     . GLY C 1 178 ? 153.578 112.210 106.980 1.00 26.78  ?  178 GLY D C     1 
ATOM 5371 O O     . GLY C 1 178 ? 154.405 113.124 107.023 1.00 26.78  ?  178 GLY D O     1 
ATOM 5372 N N     . ASN C 1 179 ? 153.460 111.401 105.934 1.00 29.10  ?  179 ASN D N     1 
ATOM 5373 C CA    . ASN C 1 179 ? 154.283 111.533 104.743 1.00 29.10  ?  179 ASN D CA    1 
ATOM 5374 C C     . ASN C 1 179 ? 153.452 112.136 103.621 1.00 29.10  ?  179 ASN D C     1 
ATOM 5375 O O     . ASN C 1 179 ? 152.354 111.652 103.329 1.00 29.10  ?  179 ASN D O     1 
ATOM 5376 C CB    . ASN C 1 179 ? 154.840 110.178 104.311 1.00 29.10  ?  179 ASN D CB    1 
ATOM 5377 C CG    . ASN C 1 179 ? 155.593 109.484 105.420 1.00 29.10  ?  179 ASN D CG    1 
ATOM 5378 O OD1   . ASN C 1 179 ? 155.294 109.671 106.599 1.00 29.10  ?  179 ASN D OD1   1 
ATOM 5379 N ND2   . ASN C 1 179 ? 156.576 108.673 105.050 1.00 29.10  ?  179 ASN D ND2   1 
ATOM 5380 N N     . ILE C 1 180 ? 153.974 113.187 102.998 1.00 24.25  ?  180 ILE D N     1 
ATOM 5381 C CA    . ILE C 1 180 ? 153.313 113.856 101.886 1.00 24.25  ?  180 ILE D CA    1 
ATOM 5382 C C     . ILE C 1 180 ? 154.255 113.834 100.693 1.00 24.25  ?  180 ILE D C     1 
ATOM 5383 O O     . ILE C 1 180 ? 155.423 114.219 100.812 1.00 24.25  ?  180 ILE D O     1 
ATOM 5384 C CB    . ILE C 1 180 ? 152.918 115.298 102.246 1.00 24.25  ?  180 ILE D CB    1 
ATOM 5385 C CG1   . ILE C 1 180 ? 151.947 115.297 103.424 1.00 24.25  ?  180 ILE D CG1   1 
ATOM 5386 C CG2   . ILE C 1 180 ? 152.304 115.992 101.050 1.00 24.25  ?  180 ILE D CG2   1 
ATOM 5387 C CD1   . ILE C 1 180 ? 151.628 116.671 103.948 1.00 24.25  ?  180 ILE D CD1   1 
ATOM 5388 N N     . LYS C 1 181 ? 153.750 113.379 99.551  1.00 34.68  ?  181 LYS D N     1 
ATOM 5389 C CA    . LYS C 1 181 ? 154.541 113.259 98.336  1.00 34.68  ?  181 LYS D CA    1 
ATOM 5390 C C     . LYS C 1 181 ? 153.863 114.027 97.212  1.00 34.68  ?  181 LYS D C     1 
ATOM 5391 O O     . LYS C 1 181 ? 152.654 113.890 97.004  1.00 34.68  ?  181 LYS D O     1 
ATOM 5392 C CB    . LYS C 1 181 ? 154.721 111.792 97.941  1.00 34.68  ?  181 LYS D CB    1 
ATOM 5393 C CG    . LYS C 1 181 ? 155.421 111.594 96.610  1.00 34.68  ?  181 LYS D CG    1 
ATOM 5394 C CD    . LYS C 1 181 ? 155.322 110.154 96.143  1.00 34.68  ?  181 LYS D CD    1 
ATOM 5395 C CE    . LYS C 1 181 ? 155.880 109.200 97.182  1.00 34.68  ?  181 LYS D CE    1 
ATOM 5396 N NZ    . LYS C 1 181 ? 157.259 109.579 97.592  1.00 34.68  1  181 LYS D NZ    1 
ATOM 5397 N N     . LEU C 1 182 ? 154.642 114.828 96.492  1.00 41.14  ?  182 LEU D N     1 
ATOM 5398 C CA    . LEU C 1 182 ? 154.149 115.585 95.350  1.00 41.14  ?  182 LEU D CA    1 
ATOM 5399 C C     . LEU C 1 182 ? 154.613 114.914 94.065  1.00 41.14  ?  182 LEU D C     1 
ATOM 5400 O O     . LEU C 1 182 ? 155.798 114.598 93.919  1.00 41.14  ?  182 LEU D O     1 
ATOM 5401 C CB    . LEU C 1 182 ? 154.643 117.031 95.395  1.00 41.14  ?  182 LEU D CB    1 
ATOM 5402 C CG    . LEU C 1 182 ? 154.105 117.905 96.526  1.00 41.14  ?  182 LEU D CG    1 
ATOM 5403 C CD1   . LEU C 1 182 ? 154.635 119.319 96.398  1.00 41.14  ?  182 LEU D CD1   1 
ATOM 5404 C CD2   . LEU C 1 182 ? 152.591 117.901 96.522  1.00 41.14  ?  182 LEU D CD2   1 
ATOM 5405 N N     . SER C 1 183 ? 153.683 114.698 93.141  1.00 50.23  ?  183 SER D N     1 
ATOM 5406 C CA    . SER C 1 183 ? 154.007 114.049 91.878  1.00 50.23  ?  183 SER D CA    1 
ATOM 5407 C C     . SER C 1 183 ? 154.571 115.078 90.908  1.00 50.23  ?  183 SER D C     1 
ATOM 5408 O O     . SER C 1 183 ? 153.903 116.065 90.583  1.00 50.23  ?  183 SER D O     1 
ATOM 5409 C CB    . SER C 1 183 ? 152.771 113.374 91.293  1.00 50.23  ?  183 SER D CB    1 
ATOM 5410 O OG    . SER C 1 183 ? 152.099 112.606 92.275  1.00 50.23  ?  183 SER D OG    1 
ATOM 5411 N N     . GLN C 1 184 ? 155.797 114.846 90.444  1.00 56.67  ?  184 GLN D N     1 
ATOM 5412 C CA    . GLN C 1 184 ? 156.458 115.767 89.526  1.00 56.67  ?  184 GLN D CA    1 
ATOM 5413 C C     . GLN C 1 184 ? 155.734 115.761 88.186  1.00 56.67  ?  184 GLN D C     1 
ATOM 5414 O O     . GLN C 1 184 ? 155.640 114.722 87.526  1.00 56.67  ?  184 GLN D O     1 
ATOM 5415 C CB    . GLN C 1 184 ? 157.921 115.375 89.351  1.00 56.67  ?  184 GLN D CB    1 
ATOM 5416 C CG    . GLN C 1 184 ? 158.579 115.987 88.130  1.00 56.67  ?  184 GLN D CG    1 
ATOM 5417 C CD    . GLN C 1 184 ? 159.899 115.329 87.792  1.00 56.67  ?  184 GLN D CD    1 
ATOM 5418 O OE1   . GLN C 1 184 ? 160.314 114.374 88.449  1.00 56.67  ?  184 GLN D OE1   1 
ATOM 5419 N NE2   . GLN C 1 184 ? 160.567 115.835 86.763  1.00 56.67  ?  184 GLN D NE2   1 
ATOM 5420 N N     . THR C 1 185 ? 155.219 116.919 87.783  1.00 75.36  ?  185 THR D N     1 
ATOM 5421 C CA    . THR C 1 185 ? 154.539 117.071 86.506  1.00 75.36  ?  185 THR D CA    1 
ATOM 5422 C C     . THR C 1 185 ? 155.043 118.323 85.804  1.00 75.36  ?  185 THR D C     1 
ATOM 5423 O O     . THR C 1 185 ? 155.189 119.380 86.425  1.00 75.36  ?  185 THR D O     1 
ATOM 5424 C CB    . THR C 1 185 ? 153.014 117.138 86.684  1.00 75.36  ?  185 THR D CB    1 
ATOM 5425 O OG1   . THR C 1 185 ? 152.400 117.502 85.441  1.00 75.36  ?  185 THR D OG1   1 
ATOM 5426 C CG2   . THR C 1 185 ? 152.634 118.148 87.757  1.00 75.36  ?  185 THR D CG2   1 
ATOM 5427 N N     . SER C 1 186 ? 155.314 118.195 84.505  1.00 98.09  ?  186 SER D N     1 
ATOM 5428 C CA    . SER C 1 186 ? 155.797 119.311 83.706  1.00 98.09  ?  186 SER D CA    1 
ATOM 5429 C C     . SER C 1 186 ? 155.065 119.481 82.383  1.00 98.09  ?  186 SER D C     1 
ATOM 5430 O O     . SER C 1 186 ? 155.255 120.510 81.726  1.00 98.09  ?  186 SER D O     1 
ATOM 5431 C CB    . SER C 1 186 ? 157.300 119.161 83.424  1.00 98.09  ?  186 SER D CB    1 
ATOM 5432 O OG    . SER C 1 186 ? 157.969 118.575 84.527  1.00 98.09  ?  186 SER D OG    1 
ATOM 5433 N N     . ASN C 1 187 ? 154.241 118.515 81.972  1.00 108.30 ?  187 ASN D N     1 
ATOM 5434 C CA    . ASN C 1 187 ? 153.500 118.619 80.721  1.00 108.30 ?  187 ASN D CA    1 
ATOM 5435 C C     . ASN C 1 187 ? 152.438 119.709 80.750  1.00 108.30 ?  187 ASN D C     1 
ATOM 5436 O O     . ASN C 1 187 ? 151.935 120.085 79.686  1.00 108.30 ?  187 ASN D O     1 
ATOM 5437 C CB    . ASN C 1 187 ? 152.848 117.277 80.391  1.00 108.30 ?  187 ASN D CB    1 
ATOM 5438 C CG    . ASN C 1 187 ? 152.117 116.678 81.577  1.00 108.30 ?  187 ASN D CG    1 
ATOM 5439 O OD1   . ASN C 1 187 ? 150.953 116.991 81.825  1.00 108.30 ?  187 ASN D OD1   1 
ATOM 5440 N ND2   . ASN C 1 187 ? 152.799 115.813 82.318  1.00 108.30 ?  187 ASN D ND2   1 
ATOM 5441 N N     . VAL C 1 188 ? 152.083 120.217 81.930  1.00 114.92 ?  188 VAL D N     1 
ATOM 5442 C CA    . VAL C 1 188 ? 151.059 121.248 82.030  1.00 114.92 ?  188 VAL D CA    1 
ATOM 5443 C C     . VAL C 1 188 ? 151.570 122.533 81.396  1.00 114.92 ?  188 VAL D C     1 
ATOM 5444 O O     . VAL C 1 188 ? 152.678 122.997 81.698  1.00 114.92 ?  188 VAL D O     1 
ATOM 5445 C CB    . VAL C 1 188 ? 150.660 121.469 83.496  1.00 114.92 ?  188 VAL D CB    1 
ATOM 5446 C CG1   . VAL C 1 188 ? 149.709 122.649 83.618  1.00 114.92 ?  188 VAL D CG1   1 
ATOM 5447 C CG2   . VAL C 1 188 ? 150.031 120.208 84.068  1.00 114.92 ?  188 VAL D CG2   1 
ATOM 5448 N N     . ASP C 1 189 ? 150.763 123.112 80.503  1.00 124.47 ?  189 ASP D N     1 
ATOM 5449 C CA    . ASP C 1 189 ? 151.149 124.363 79.858  1.00 124.47 ?  189 ASP D CA    1 
ATOM 5450 C C     . ASP C 1 189 ? 151.255 125.496 80.871  1.00 124.47 ?  189 ASP D C     1 
ATOM 5451 O O     . ASP C 1 189 ? 152.175 126.320 80.798  1.00 124.47 ?  189 ASP D O     1 
ATOM 5452 C CB    . ASP C 1 189 ? 150.148 124.715 78.758  1.00 124.47 ?  189 ASP D CB    1 
ATOM 5453 C CG    . ASP C 1 189 ? 148.709 124.552 79.205  1.00 124.47 ?  189 ASP D CG    1 
ATOM 5454 O OD1   . ASP C 1 189 ? 148.227 125.402 79.982  1.00 124.47 ?  189 ASP D OD1   1 
ATOM 5455 O OD2   . ASP C 1 189 ? 148.061 123.573 78.780  1.00 124.47 -1 189 ASP D OD2   1 
ATOM 5456 N N     . LYS C 1 190 ? 150.326 125.555 81.821  1.00 118.15 ?  190 LYS D N     1 
ATOM 5457 C CA    . LYS C 1 190 ? 150.356 126.574 82.867  1.00 118.15 ?  190 LYS D CA    1 
ATOM 5458 C C     . LYS C 1 190 ? 151.529 126.287 83.793  1.00 118.15 ?  190 LYS D C     1 
ATOM 5459 O O     . LYS C 1 190 ? 151.479 125.370 84.615  1.00 118.15 ?  190 LYS D O     1 
ATOM 5460 C CB    . LYS C 1 190 ? 149.040 126.593 83.635  1.00 118.15 ?  190 LYS D CB    1 
ATOM 5461 C CG    . LYS C 1 190 ? 147.835 126.979 82.797  1.00 118.15 ?  190 LYS D CG    1 
ATOM 5462 C CD    . LYS C 1 190 ? 146.563 126.353 83.342  1.00 118.15 ?  190 LYS D CD    1 
ATOM 5463 C CE    . LYS C 1 190 ? 146.649 124.835 83.338  1.00 118.15 ?  190 LYS D CE    1 
ATOM 5464 N NZ    . LYS C 1 190 ? 147.149 124.309 82.038  1.00 118.15 1  190 LYS D NZ    1 
ATOM 5465 N N     . GLU C 1 191 ? 152.599 127.074 83.658  1.00 112.51 ?  191 GLU D N     1 
ATOM 5466 C CA    . GLU C 1 191 ? 153.780 126.874 84.489  1.00 112.51 ?  191 GLU D CA    1 
ATOM 5467 C C     . GLU C 1 191 ? 153.516 127.179 85.956  1.00 112.51 ?  191 GLU D C     1 
ATOM 5468 O O     . GLU C 1 191 ? 154.240 126.672 86.820  1.00 112.51 ?  191 GLU D O     1 
ATOM 5469 C CB    . GLU C 1 191 ? 154.933 127.736 83.974  1.00 112.51 ?  191 GLU D CB    1 
ATOM 5470 C CG    . GLU C 1 191 ? 154.886 128.000 82.477  1.00 112.51 ?  191 GLU D CG    1 
ATOM 5471 C CD    . GLU C 1 191 ? 155.236 126.775 81.652  1.00 112.51 ?  191 GLU D CD    1 
ATOM 5472 O OE1   . GLU C 1 191 ? 155.715 125.777 82.230  1.00 112.51 ?  191 GLU D OE1   1 
ATOM 5473 O OE2   . GLU C 1 191 ? 155.029 126.810 80.420  1.00 112.51 -1 191 GLU D OE2   1 
ATOM 5474 N N     . GLU C 1 192 ? 152.503 127.996 86.256  1.00 100.54 ?  192 GLU D N     1 
ATOM 5475 C CA    . GLU C 1 192 ? 152.160 128.262 87.648  1.00 100.54 ?  192 GLU D CA    1 
ATOM 5476 C C     . GLU C 1 192 ? 151.704 126.992 88.354  1.00 100.54 ?  192 GLU D C     1 
ATOM 5477 O O     . GLU C 1 192 ? 152.092 126.736 89.499  1.00 100.54 ?  192 GLU D O     1 
ATOM 5478 C CB    . GLU C 1 192 ? 151.079 129.342 87.726  1.00 100.54 ?  192 GLU D CB    1 
ATOM 5479 C CG    . GLU C 1 192 ? 149.891 129.118 86.800  1.00 100.54 ?  192 GLU D CG    1 
ATOM 5480 C CD    . GLU C 1 192 ? 150.085 129.747 85.435  1.00 100.54 ?  192 GLU D CD    1 
ATOM 5481 O OE1   . GLU C 1 192 ? 150.980 129.293 84.691  1.00 100.54 ?  192 GLU D OE1   1 
ATOM 5482 O OE2   . GLU C 1 192 ? 149.341 130.695 85.104  1.00 100.54 -1 192 GLU D OE2   1 
ATOM 5483 N N     . GLU C 1 193 ? 150.884 126.184 87.688  1.00 91.68  ?  193 GLU D N     1 
ATOM 5484 C CA    . GLU C 1 193 ? 150.411 124.918 88.244  1.00 91.68  ?  193 GLU D CA    1 
ATOM 5485 C C     . GLU C 1 193 ? 151.301 123.754 87.821  1.00 91.68  ?  193 GLU D C     1 
ATOM 5486 O O     . GLU C 1 193 ? 150.833 122.747 87.291  1.00 91.68  ?  193 GLU D O     1 
ATOM 5487 C CB    . GLU C 1 193 ? 148.965 124.678 87.829  1.00 91.68  ?  193 GLU D CB    1 
ATOM 5488 C CG    . GLU C 1 193 ? 147.992 124.592 88.991  1.00 91.68  ?  193 GLU D CG    1 
ATOM 5489 C CD    . GLU C 1 193 ? 148.213 123.359 89.845  1.00 91.68  ?  193 GLU D CD    1 
ATOM 5490 O OE1   . GLU C 1 193 ? 148.750 122.359 89.324  1.00 91.68  ?  193 GLU D OE1   1 
ATOM 5491 O OE2   . GLU C 1 193 ? 147.848 123.390 91.039  1.00 91.68  -1 193 GLU D OE2   1 
ATOM 5492 N N     . ALA C 1 194 ? 152.604 123.886 88.057  1.00 71.71  ?  194 ALA D N     1 
ATOM 5493 C CA    . ALA C 1 194 ? 153.560 122.852 87.697  1.00 71.71  ?  194 ALA D CA    1 
ATOM 5494 C C     . ALA C 1 194 ? 154.622 122.744 88.779  1.00 71.71  ?  194 ALA D C     1 
ATOM 5495 O O     . ALA C 1 194 ? 154.958 123.728 89.442  1.00 71.71  ?  194 ALA D O     1 
ATOM 5496 C CB    . ALA C 1 194 ? 154.221 123.140 86.344  1.00 71.71  ?  194 ALA D CB    1 
ATOM 5497 N N     . VAL C 1 195 ? 155.147 121.535 88.951  1.00 50.92  ?  195 VAL D N     1 
ATOM 5498 C CA    . VAL C 1 195 ? 156.240 121.268 89.876  1.00 50.92  ?  195 VAL D CA    1 
ATOM 5499 C C     . VAL C 1 195 ? 157.390 120.665 89.082  1.00 50.92  ?  195 VAL D C     1 
ATOM 5500 O O     . VAL C 1 195 ? 157.216 119.653 88.392  1.00 50.92  ?  195 VAL D O     1 
ATOM 5501 C CB    . VAL C 1 195 ? 155.807 120.349 91.031  1.00 50.92  ?  195 VAL D CB    1 
ATOM 5502 C CG1   . VAL C 1 195 ? 155.103 119.112 90.507  1.00 50.92  ?  195 VAL D CG1   1 
ATOM 5503 C CG2   . VAL C 1 195 ? 157.009 119.956 91.866  1.00 50.92  ?  195 VAL D CG2   1 
ATOM 5504 N N     . THR C 1 196 ? 158.557 121.296 89.163  1.00 43.15  ?  196 THR D N     1 
ATOM 5505 C CA    . THR C 1 196 ? 159.731 120.868 88.418  1.00 43.15  ?  196 THR D CA    1 
ATOM 5506 C C     . THR C 1 196 ? 160.894 120.699 89.381  1.00 43.15  ?  196 THR D C     1 
ATOM 5507 O O     . THR C 1 196 ? 161.207 121.615 90.147  1.00 43.15  ?  196 THR D O     1 
ATOM 5508 C CB    . THR C 1 196 ? 160.091 121.877 87.324  1.00 43.15  ?  196 THR D CB    1 
ATOM 5509 O OG1   . THR C 1 196 ? 159.097 121.840 86.293  1.00 43.15  ?  196 THR D OG1   1 
ATOM 5510 C CG2   . THR C 1 196 ? 161.448 121.551 86.723  1.00 43.15  ?  196 THR D CG2   1 
ATOM 5511 N N     . ILE C 1 197 ? 161.530 119.533 89.340  1.00 45.20  ?  197 ILE D N     1 
ATOM 5512 C CA    . ILE C 1 197 ? 162.647 119.205 90.214  1.00 45.20  ?  197 ILE D CA    1 
ATOM 5513 C C     . ILE C 1 197 ? 163.855 118.874 89.352  1.00 45.20  ?  197 ILE D C     1 
ATOM 5514 O O     . ILE C 1 197 ? 163.747 118.111 88.386  1.00 45.20  ?  197 ILE D O     1 
ATOM 5515 C CB    . ILE C 1 197 ? 162.304 118.039 91.160  1.00 45.20  ?  197 ILE D CB    1 
ATOM 5516 C CG1   . ILE C 1 197 ? 163.528 117.637 91.980  1.00 45.20  ?  197 ILE D CG1   1 
ATOM 5517 C CG2   . ILE C 1 197 ? 161.744 116.856 90.388  1.00 45.20  ?  197 ILE D CG2   1 
ATOM 5518 C CD1   . ILE C 1 197 ? 163.240 116.575 93.003  1.00 45.20  ?  197 ILE D CD1   1 
ATOM 5519 N N     . GLU C 1 198 ? 164.997 119.466 89.686  1.00 51.06  ?  198 GLU D N     1 
ATOM 5520 C CA    . GLU C 1 198 ? 166.252 119.215 88.991  1.00 51.06  ?  198 GLU D CA    1 
ATOM 5521 C C     . GLU C 1 198 ? 167.256 118.655 89.989  1.00 51.06  ?  198 GLU D C     1 
ATOM 5522 O O     . GLU C 1 198 ? 167.561 119.300 90.997  1.00 51.06  ?  198 GLU D O     1 
ATOM 5523 C CB    . GLU C 1 198 ? 166.781 120.494 88.342  1.00 51.06  ?  198 GLU D CB    1 
ATOM 5524 C CG    . GLU C 1 198 ? 167.847 120.263 87.288  1.00 51.06  ?  198 GLU D CG    1 
ATOM 5525 C CD    . GLU C 1 198 ? 169.236 120.160 87.881  1.00 51.06  ?  198 GLU D CD    1 
ATOM 5526 O OE1   . GLU C 1 198 ? 169.428 120.611 89.029  1.00 51.06  ?  198 GLU D OE1   1 
ATOM 5527 O OE2   . GLU C 1 198 ? 170.137 119.628 87.199  1.00 51.06  -1 198 GLU D OE2   1 
ATOM 5528 N N     . MET C 1 199 ? 167.769 117.463 89.702  1.00 61.77  ?  199 MET D N     1 
ATOM 5529 C CA    . MET C 1 199 ? 168.689 116.760 90.583  1.00 61.77  ?  199 MET D CA    1 
ATOM 5530 C C     . MET C 1 199 ? 170.121 116.832 90.079  1.00 61.77  ?  199 MET D C     1 
ATOM 5531 O O     . MET C 1 199 ? 170.381 116.706 88.878  1.00 61.77  ?  199 MET D O     1 
ATOM 5532 C CB    . MET C 1 199 ? 168.290 115.292 90.742  1.00 61.77  ?  199 MET D CB    1 
ATOM 5533 C CG    . MET C 1 199 ? 168.347 114.792 92.170  1.00 61.77  ?  199 MET D CG    1 
ATOM 5534 S SD    . MET C 1 199 ? 167.435 115.756 93.379  1.00 61.77  ?  199 MET D SD    1 
ATOM 5535 C CE    . MET C 1 199 ? 167.711 114.732 94.819  1.00 61.77  ?  199 MET D CE    1 
ATOM 5536 N N     . ASN C 1 200 ? 171.040 117.035 91.014  1.00 73.42  ?  200 ASN D N     1 
ATOM 5537 C CA    . ASN C 1 200 ? 172.460 116.811 90.801  1.00 73.42  ?  200 ASN D CA    1 
ATOM 5538 C C     . ASN C 1 200 ? 173.029 115.747 91.723  1.00 73.42  ?  200 ASN D C     1 
ATOM 5539 O O     . ASN C 1 200 ? 173.993 115.076 91.350  1.00 73.42  ?  200 ASN D O     1 
ATOM 5540 C CB    . ASN C 1 200 ? 173.246 118.117 90.995  1.00 73.42  ?  200 ASN D CB    1 
ATOM 5541 C CG    . ASN C 1 200 ? 174.691 117.995 90.561  1.00 73.42  ?  200 ASN D CG    1 
ATOM 5542 O OD1   . ASN C 1 200 ? 175.030 117.163 89.720  1.00 73.42  ?  200 ASN D OD1   1 
ATOM 5543 N ND2   . ASN C 1 200 ? 175.554 118.825 91.135  1.00 73.42  ?  200 ASN D ND2   1 
ATOM 5544 N N     . GLU C 1 201 ? 172.448 115.571 92.909  1.00 82.47  ?  201 GLU D N     1 
ATOM 5545 C CA    . GLU C 1 201 ? 172.861 114.559 93.871  1.00 82.47  ?  201 GLU D CA    1 
ATOM 5546 C C     . GLU C 1 201 ? 171.755 114.417 94.904  1.00 82.47  ?  201 GLU D C     1 
ATOM 5547 O O     . GLU C 1 201 ? 171.033 115.386 95.162  1.00 82.47  ?  201 GLU D O     1 
ATOM 5548 C CB    . GLU C 1 201 ? 174.184 114.943 94.548  1.00 82.47  ?  201 GLU D CB    1 
ATOM 5549 C CG    . GLU C 1 201 ? 175.356 114.058 94.163  1.00 82.47  ?  201 GLU D CG    1 
ATOM 5550 C CD    . GLU C 1 201 ? 176.591 114.333 94.997  1.00 82.47  ?  201 GLU D CD    1 
ATOM 5551 O OE1   . GLU C 1 201 ? 176.526 115.210 95.884  1.00 82.47  ?  201 GLU D OE1   1 
ATOM 5552 O OE2   . GLU C 1 201 ? 177.626 113.674 94.765  1.00 82.47  -1 201 GLU D OE2   1 
ATOM 5553 N N     . PRO C 1 202 ? 171.586 113.240 95.501  1.00 77.40  ?  202 PRO D N     1 
ATOM 5554 C CA    . PRO C 1 202 ? 170.543 113.083 96.521  1.00 77.40  ?  202 PRO D CA    1 
ATOM 5555 C C     . PRO C 1 202 ? 170.867 113.884 97.772  1.00 77.40  ?  202 PRO D C     1 
ATOM 5556 O O     . PRO C 1 202 ? 172.029 114.153 98.085  1.00 77.40  ?  202 PRO D O     1 
ATOM 5557 C CB    . PRO C 1 202 ? 170.528 111.577 96.811  1.00 77.40  ?  202 PRO D CB    1 
ATOM 5558 C CG    . PRO C 1 202 ? 171.653 110.975 96.047  1.00 77.40  ?  202 PRO D CG    1 
ATOM 5559 C CD    . PRO C 1 202 ? 172.420 112.037 95.342  1.00 77.40  ?  202 PRO D CD    1 
ATOM 5560 N N     . VAL C 1 203 ? 169.813 114.272 98.490  1.00 59.53  ?  203 VAL D N     1 
ATOM 5561 C CA    . VAL C 1 203 ? 169.961 115.097 99.682  1.00 59.53  ?  203 VAL D CA    1 
ATOM 5562 C C     . VAL C 1 203 ? 168.788 114.817 100.608 1.00 59.53  ?  203 VAL D C     1 
ATOM 5563 O O     . VAL C 1 203 ? 167.677 114.527 100.157 1.00 59.53  ?  203 VAL D O     1 
ATOM 5564 C CB    . VAL C 1 203 ? 170.059 116.599 99.310  1.00 59.53  ?  203 VAL D CB    1 
ATOM 5565 C CG1   . VAL C 1 203 ? 168.776 117.068 98.645  1.00 59.53  ?  203 VAL D CG1   1 
ATOM 5566 C CG2   . VAL C 1 203 ? 170.375 117.440 100.536 1.00 59.53  ?  203 VAL D CG2   1 
ATOM 5567 N N     . GLN C 1 204 ? 169.044 114.891 101.913 1.00 47.19  ?  204 GLN D N     1 
ATOM 5568 C CA    . GLN C 1 204 ? 168.011 114.752 102.931 1.00 47.19  ?  204 GLN D CA    1 
ATOM 5569 C C     . GLN C 1 204 ? 168.358 115.674 104.089 1.00 47.19  ?  204 GLN D C     1 
ATOM 5570 O O     . GLN C 1 204 ? 169.468 115.606 104.625 1.00 47.19  ?  204 GLN D O     1 
ATOM 5571 C CB    . GLN C 1 204 ? 167.893 113.301 103.410 1.00 47.19  ?  204 GLN D CB    1 
ATOM 5572 C CG    . GLN C 1 204 ? 167.495 113.151 104.866 1.00 47.19  ?  204 GLN D CG    1 
ATOM 5573 C CD    . GLN C 1 204 ? 166.728 111.872 105.127 1.00 47.19  ?  204 GLN D CD    1 
ATOM 5574 O OE1   . GLN C 1 204 ? 166.485 111.084 104.213 1.00 47.19  ?  204 GLN D OE1   1 
ATOM 5575 N NE2   . GLN C 1 204 ? 166.343 111.658 106.379 1.00 47.19  ?  204 GLN D NE2   1 
ATOM 5576 N N     . LEU C 1 205 ? 167.416 116.533 104.469 1.00 41.03  ?  205 LEU D N     1 
ATOM 5577 C CA    . LEU C 1 205 ? 167.659 117.579 105.453 1.00 41.03  ?  205 LEU D CA    1 
ATOM 5578 C C     . LEU C 1 205 ? 166.547 117.579 106.494 1.00 41.03  ?  205 LEU D C     1 
ATOM 5579 O O     . LEU C 1 205 ? 165.621 116.765 106.453 1.00 41.03  ?  205 LEU D O     1 
ATOM 5580 C CB    . LEU C 1 205 ? 167.767 118.951 104.777 1.00 41.03  ?  205 LEU D CB    1 
ATOM 5581 C CG    . LEU C 1 205 ? 168.790 119.079 103.648 1.00 41.03  ?  205 LEU D CG    1 
ATOM 5582 C CD1   . LEU C 1 205 ? 168.797 120.492 103.097 1.00 41.03  ?  205 LEU D CD1   1 
ATOM 5583 C CD2   . LEU C 1 205 ? 170.174 118.694 104.137 1.00 41.03  ?  205 LEU D CD2   1 
ATOM 5584 N N     . THR C 1 206 ? 166.649 118.511 107.440 1.00 40.12  ?  206 THR D N     1 
ATOM 5585 C CA    . THR C 1 206 ? 165.656 118.679 108.490 1.00 40.12  ?  206 THR D CA    1 
ATOM 5586 C C     . THR C 1 206 ? 165.530 120.161 108.805 1.00 40.12  ?  206 THR D C     1 
ATOM 5587 O O     . THR C 1 206 ? 166.505 120.910 108.713 1.00 40.12  ?  206 THR D O     1 
ATOM 5588 C CB    . THR C 1 206 ? 166.031 117.901 109.755 1.00 40.12  ?  206 THR D CB    1 
ATOM 5589 O OG1   . THR C 1 206 ? 166.599 116.638 109.391 1.00 40.12  ?  206 THR D OG1   1 
ATOM 5590 C CG2   . THR C 1 206 ? 164.804 117.666 110.619 1.00 40.12  ?  206 THR D CG2   1 
ATOM 5591 N N     . PHE C 1 207 ? 164.323 120.582 109.178 1.00 37.69  ?  207 PHE D N     1 
ATOM 5592 C CA    . PHE C 1 207 ? 164.060 121.990 109.440 1.00 37.69  ?  207 PHE D CA    1 
ATOM 5593 C C     . PHE C 1 207 ? 163.002 122.115 110.526 1.00 37.69  ?  207 PHE D C     1 
ATOM 5594 O O     . PHE C 1 207 ? 162.386 121.132 110.942 1.00 37.69  ?  207 PHE D O     1 
ATOM 5595 C CB    . PHE C 1 207 ? 163.620 122.720 108.169 1.00 37.69  ?  207 PHE D CB    1 
ATOM 5596 C CG    . PHE C 1 207 ? 164.602 122.616 107.045 1.00 37.69  ?  207 PHE D CG    1 
ATOM 5597 C CD1   . PHE C 1 207 ? 165.692 123.462 106.983 1.00 37.69  ?  207 PHE D CD1   1 
ATOM 5598 C CD2   . PHE C 1 207 ? 164.443 121.665 106.055 1.00 37.69  ?  207 PHE D CD2   1 
ATOM 5599 C CE1   . PHE C 1 207 ? 166.602 123.364 105.953 1.00 37.69  ?  207 PHE D CE1   1 
ATOM 5600 C CE2   . PHE C 1 207 ? 165.350 121.564 105.023 1.00 37.69  ?  207 PHE D CE2   1 
ATOM 5601 C CZ    . PHE C 1 207 ? 166.430 122.416 104.972 1.00 37.69  ?  207 PHE D CZ    1 
ATOM 5602 N N     . ALA C 1 208 ? 162.799 123.347 110.982 1.00 38.85  ?  208 ALA D N     1 
ATOM 5603 C CA    . ALA C 1 208 ? 161.830 123.652 112.025 1.00 38.85  ?  208 ALA D CA    1 
ATOM 5604 C C     . ALA C 1 208 ? 160.548 124.174 111.394 1.00 38.85  ?  208 ALA D C     1 
ATOM 5605 O O     . ALA C 1 208 ? 160.590 125.049 110.523 1.00 38.85  ?  208 ALA D O     1 
ATOM 5606 C CB    . ALA C 1 208 ? 162.392 124.678 113.009 1.00 38.85  ?  208 ALA D CB    1 
ATOM 5607 N N     . LEU C 1 209 ? 159.410 123.638 111.840 1.00 40.46  ?  209 LEU D N     1 
ATOM 5608 C CA    . LEU C 1 209 ? 158.137 123.984 111.219 1.00 40.46  ?  209 LEU D CA    1 
ATOM 5609 C C     . LEU C 1 209 ? 157.702 125.406 111.539 1.00 40.46  ?  209 LEU D C     1 
ATOM 5610 O O     . LEU C 1 209 ? 157.036 126.044 110.715 1.00 40.46  ?  209 LEU D O     1 
ATOM 5611 C CB    . LEU C 1 209 ? 157.060 122.994 111.648 1.00 40.46  ?  209 LEU D CB    1 
ATOM 5612 C CG    . LEU C 1 209 ? 156.714 121.994 110.551 1.00 40.46  ?  209 LEU D CG    1 
ATOM 5613 C CD1   . LEU C 1 209 ? 155.632 121.047 111.003 1.00 40.46  ?  209 LEU D CD1   1 
ATOM 5614 C CD2   . LEU C 1 209 ? 156.280 122.736 109.304 1.00 40.46  ?  209 LEU D CD2   1 
ATOM 5615 N N     . ARG C 1 210 ? 158.044 125.916 112.723 1.00 46.25  ?  210 ARG D N     1 
ATOM 5616 C CA    . ARG C 1 210 ? 157.647 127.275 113.074 1.00 46.25  ?  210 ARG D CA    1 
ATOM 5617 C C     . ARG C 1 210 ? 158.236 128.284 112.099 1.00 46.25  ?  210 ARG D C     1 
ATOM 5618 O O     . ARG C 1 210 ? 157.545 129.207 111.648 1.00 46.25  ?  210 ARG D O     1 
ATOM 5619 C CB    . ARG C 1 210 ? 158.080 127.594 114.503 1.00 46.25  ?  210 ARG D CB    1 
ATOM 5620 C CG    . ARG C 1 210 ? 157.264 128.684 115.171 1.00 46.25  ?  210 ARG D CG    1 
ATOM 5621 C CD    . ARG C 1 210 ? 157.521 128.715 116.667 1.00 46.25  ?  210 ARG D CD    1 
ATOM 5622 N NE    . ARG C 1 210 ? 158.923 128.979 116.971 1.00 46.25  ?  210 ARG D NE    1 
ATOM 5623 C CZ    . ARG C 1 210 ? 159.435 130.189 117.147 1.00 46.25  ?  210 ARG D CZ    1 
ATOM 5624 N NH1   . ARG C 1 210 ? 158.685 131.275 117.066 1.00 46.25  1  210 ARG D NH1   1 
ATOM 5625 N NH2   . ARG C 1 210 ? 160.733 130.311 117.411 1.00 46.25  ?  210 ARG D NH2   1 
ATOM 5626 N N     . TYR C 1 211 ? 159.508 128.112 111.744 1.00 46.24  ?  211 TYR D N     1 
ATOM 5627 C CA    . TYR C 1 211 ? 160.137 129.044 110.818 1.00 46.24  ?  211 TYR D CA    1 
ATOM 5628 C C     . TYR C 1 211 ? 159.553 128.916 109.417 1.00 46.24  ?  211 TYR D C     1 
ATOM 5629 O O     . TYR C 1 211 ? 159.413 129.916 108.710 1.00 46.24  ?  211 TYR D O     1 
ATOM 5630 C CB    . TYR C 1 211 ? 161.648 128.832 110.807 1.00 46.24  ?  211 TYR D CB    1 
ATOM 5631 C CG    . TYR C 1 211 ? 162.330 129.484 111.982 1.00 46.24  ?  211 TYR D CG    1 
ATOM 5632 C CD1   . TYR C 1 211 ? 161.858 130.680 112.502 1.00 46.24  ?  211 TYR D CD1   1 
ATOM 5633 C CD2   . TYR C 1 211 ? 163.437 128.902 112.580 1.00 46.24  ?  211 TYR D CD2   1 
ATOM 5634 C CE1   . TYR C 1 211 ? 162.471 131.282 113.578 1.00 46.24  ?  211 TYR D CE1   1 
ATOM 5635 C CE2   . TYR C 1 211 ? 164.056 129.497 113.658 1.00 46.24  ?  211 TYR D CE2   1 
ATOM 5636 C CZ    . TYR C 1 211 ? 163.570 130.687 114.153 1.00 46.24  ?  211 TYR D CZ    1 
ATOM 5637 O OH    . TYR C 1 211 ? 164.185 131.283 115.227 1.00 46.24  ?  211 TYR D OH    1 
ATOM 5638 N N     . LEU C 1 212 ? 159.198 127.701 108.996 1.00 37.46  ?  212 LEU D N     1 
ATOM 5639 C CA    . LEU C 1 212 ? 158.570 127.550 107.687 1.00 37.46  ?  212 LEU D CA    1 
ATOM 5640 C C     . LEU C 1 212 ? 157.196 128.210 107.654 1.00 37.46  ?  212 LEU D C     1 
ATOM 5641 O O     . LEU C 1 212 ? 156.824 128.839 106.655 1.00 37.46  ?  212 LEU D O     1 
ATOM 5642 C CB    . LEU C 1 212 ? 158.473 126.073 107.318 1.00 37.46  ?  212 LEU D CB    1 
ATOM 5643 C CG    . LEU C 1 212 ? 159.798 125.395 106.968 1.00 37.46  ?  212 LEU D CG    1 
ATOM 5644 C CD1   . LEU C 1 212 ? 159.558 124.149 106.137 1.00 37.46  ?  212 LEU D CD1   1 
ATOM 5645 C CD2   . LEU C 1 212 ? 160.715 126.355 106.236 1.00 37.46  ?  212 LEU D CD2   1 
ATOM 5646 N N     . ASN C 1 213 ? 156.429 128.077 108.738 1.00 40.66  ?  213 ASN D N     1 
ATOM 5647 C CA    . ASN C 1 213 ? 155.140 128.755 108.813 1.00 40.66  ?  213 ASN D CA    1 
ATOM 5648 C C     . ASN C 1 213 ? 155.315 130.266 108.789 1.00 40.66  ?  213 ASN D C     1 
ATOM 5649 O O     . ASN C 1 213 ? 154.519 130.980 108.169 1.00 40.66  ?  213 ASN D O     1 
ATOM 5650 C CB    . ASN C 1 213 ? 154.388 128.320 110.069 1.00 40.66  ?  213 ASN D CB    1 
ATOM 5651 C CG    . ASN C 1 213 ? 153.763 126.951 109.924 1.00 40.66  ?  213 ASN D CG    1 
ATOM 5652 O OD1   . ASN C 1 213 ? 153.476 126.279 110.913 1.00 40.66  ?  213 ASN D OD1   1 
ATOM 5653 N ND2   . ASN C 1 213 ? 153.552 126.527 108.684 1.00 40.66  ?  213 ASN D ND2   1 
ATOM 5654 N N     . PHE C 1 214 ? 156.347 130.773 109.467 1.00 44.90  ?  214 PHE D N     1 
ATOM 5655 C CA    . PHE C 1 214 ? 156.645 132.200 109.385 1.00 44.90  ?  214 PHE D CA    1 
ATOM 5656 C C     . PHE C 1 214 ? 157.006 132.604 107.961 1.00 44.90  ?  214 PHE D C     1 
ATOM 5657 O O     . PHE C 1 214 ? 156.588 133.663 107.482 1.00 44.90  ?  214 PHE D O     1 
ATOM 5658 C CB    . PHE C 1 214 ? 157.781 132.557 110.341 1.00 44.90  ?  214 PHE D CB    1 
ATOM 5659 C CG    . PHE C 1 214 ? 157.345 132.715 111.765 1.00 44.90  ?  214 PHE D CG    1 
ATOM 5660 C CD1   . PHE C 1 214 ? 156.119 133.278 112.068 1.00 44.90  ?  214 PHE D CD1   1 
ATOM 5661 C CD2   . PHE C 1 214 ? 158.163 132.304 112.802 1.00 44.90  ?  214 PHE D CD2   1 
ATOM 5662 C CE1   . PHE C 1 214 ? 155.715 133.426 113.379 1.00 44.90  ?  214 PHE D CE1   1 
ATOM 5663 C CE2   . PHE C 1 214 ? 157.765 132.449 114.114 1.00 44.90  ?  214 PHE D CE2   1 
ATOM 5664 C CZ    . PHE C 1 214 ? 156.539 133.011 114.404 1.00 44.90  ?  214 PHE D CZ    1 
ATOM 5665 N N     . PHE C 1 215 ? 157.789 131.770 107.274 1.00 42.05  ?  215 PHE D N     1 
ATOM 5666 C CA    . PHE C 1 215 ? 158.214 132.083 105.914 1.00 42.05  ?  215 PHE D CA    1 
ATOM 5667 C C     . PHE C 1 215 ? 157.024 132.153 104.969 1.00 42.05  ?  215 PHE D C     1 
ATOM 5668 O O     . PHE C 1 215 ? 156.956 133.037 104.107 1.00 42.05  ?  215 PHE D O     1 
ATOM 5669 C CB    . PHE C 1 215 ? 159.213 131.038 105.415 1.00 42.05  ?  215 PHE D CB    1 
ATOM 5670 C CG    . PHE C 1 215 ? 160.555 131.085 106.094 1.00 42.05  ?  215 PHE D CG    1 
ATOM 5671 C CD1   . PHE C 1 215 ? 160.818 131.993 107.106 1.00 42.05  ?  215 PHE D CD1   1 
ATOM 5672 C CD2   . PHE C 1 215 ? 161.558 130.216 105.708 1.00 42.05  ?  215 PHE D CD2   1 
ATOM 5673 C CE1   . PHE C 1 215 ? 162.052 132.027 107.719 1.00 42.05  ?  215 PHE D CE1   1 
ATOM 5674 C CE2   . PHE C 1 215 ? 162.793 130.247 106.317 1.00 42.05  ?  215 PHE D CE2   1 
ATOM 5675 C CZ    . PHE C 1 215 ? 163.040 131.153 107.323 1.00 42.05  ?  215 PHE D CZ    1 
ATOM 5676 N N     . THR C 1 216 ? 156.079 131.232 105.115 1.00 37.46  ?  216 THR D N     1 
ATOM 5677 C CA    . THR C 1 216 ? 154.955 131.143 104.179 1.00 37.46  ?  216 THR D CA    1 
ATOM 5678 C C     . THR C 1 216 ? 153.988 132.316 104.270 1.00 37.46  ?  216 THR D C     1 
ATOM 5679 O O     . THR C 1 216 ? 152.963 132.264 103.581 1.00 37.46  ?  216 THR D O     1 
ATOM 5680 C CB    . THR C 1 216 ? 154.189 129.840 104.398 1.00 37.46  ?  216 THR D CB    1 
ATOM 5681 O OG1   . THR C 1 216 ? 153.943 129.660 105.798 1.00 37.46  ?  216 THR D OG1   1 
ATOM 5682 C CG2   . THR C 1 216 ? 154.989 128.664 103.874 1.00 37.46  ?  216 THR D CG2   1 
ATOM 5683 N N     . LYS C 1 217 ? 154.233 133.357 105.066 1.00 38.45  ?  217 LYS D N     1 
ATOM 5684 C CA    . LYS C 1 217 ? 153.314 134.487 105.117 1.00 38.45  ?  217 LYS D CA    1 
ATOM 5685 C C     . LYS C 1 217 ? 153.349 135.335 103.853 1.00 38.45  ?  217 LYS D C     1 
ATOM 5686 O O     . LYS C 1 217 ? 152.461 136.173 103.669 1.00 38.45  ?  217 LYS D O     1 
ATOM 5687 C CB    . LYS C 1 217 ? 153.624 135.365 106.329 1.00 38.45  ?  217 LYS D CB    1 
ATOM 5688 C CG    . LYS C 1 217 ? 153.387 134.683 107.662 1.00 38.45  ?  217 LYS D CG    1 
ATOM 5689 C CD    . LYS C 1 217 ? 151.916 134.370 107.865 1.00 38.45  ?  217 LYS D CD    1 
ATOM 5690 C CE    . LYS C 1 217 ? 151.674 133.725 109.218 1.00 38.45  ?  217 LYS D CE    1 
ATOM 5691 N NZ    . LYS C 1 217 ? 150.255 133.311 109.388 1.00 38.45  1  217 LYS D NZ    1 
ATOM 5692 N N     . ALA C 1 218 ? 154.342 135.142 102.984 1.00 34.19  ?  218 ALA D N     1 
ATOM 5693 C CA    . ALA C 1 218 ? 154.466 135.911 101.752 1.00 34.19  ?  218 ALA D CA    1 
ATOM 5694 C C     . ALA C 1 218 ? 153.819 135.219 100.560 1.00 34.19  ?  218 ALA D C     1 
ATOM 5695 O O     . ALA C 1 218 ? 154.263 135.411 99.421  1.00 34.19  ?  218 ALA D O     1 
ATOM 5696 C CB    . ALA C 1 218 ? 155.938 136.201 101.463 1.00 34.19  ?  218 ALA D CB    1 
ATOM 5697 N N     . THR C 1 219 ? 152.787 134.411 100.795 1.00 34.40  ?  219 THR D N     1 
ATOM 5698 C CA    . THR C 1 219 ? 152.128 133.701 99.700  1.00 34.40  ?  219 THR D CA    1 
ATOM 5699 C C     . THR C 1 219 ? 151.520 134.629 98.653  1.00 34.40  ?  219 THR D C     1 
ATOM 5700 O O     . THR C 1 219 ? 151.740 134.389 97.453  1.00 34.40  ?  219 THR D O     1 
ATOM 5701 C CB    . THR C 1 219 ? 151.079 132.741 100.274 1.00 34.40  ?  219 THR D CB    1 
ATOM 5702 O OG1   . THR C 1 219 ? 151.726 131.550 100.736 1.00 34.40  ?  219 THR D OG1   1 
ATOM 5703 C CG2   . THR C 1 219 ? 150.050 132.372 99.220  1.00 34.40  ?  219 THR D CG2   1 
ATOM 5704 N N     . PRO C 1 220 ? 150.770 135.683 99.002  1.00 32.19  ?  220 PRO D N     1 
ATOM 5705 C CA    . PRO C 1 220 ? 150.137 136.502 97.954  1.00 32.19  ?  220 PRO D CA    1 
ATOM 5706 C C     . PRO C 1 220 ? 151.119 137.214 97.040  1.00 32.19  ?  220 PRO D C     1 
ATOM 5707 O O     . PRO C 1 220 ? 150.704 137.688 95.975  1.00 32.19  ?  220 PRO D O     1 
ATOM 5708 C CB    . PRO C 1 220 ? 149.295 137.510 98.749  1.00 32.19  ?  220 PRO D CB    1 
ATOM 5709 C CG    . PRO C 1 220 ? 149.113 136.889 100.082 1.00 32.19  ?  220 PRO D CG    1 
ATOM 5710 C CD    . PRO C 1 220 ? 150.381 136.154 100.343 1.00 32.19  ?  220 PRO D CD    1 
ATOM 5711 N N     . LEU C 1 221 ? 152.394 137.316 97.420  1.00 34.83  ?  221 LEU D N     1 
ATOM 5712 C CA    . LEU C 1 221 ? 153.357 138.037 96.594  1.00 34.83  ?  221 LEU D CA    1 
ATOM 5713 C C     . LEU C 1 221 ? 153.530 137.380 95.231  1.00 34.83  ?  221 LEU D C     1 
ATOM 5714 O O     . LEU C 1 221 ? 153.582 138.067 94.205  1.00 34.83  ?  221 LEU D O     1 
ATOM 5715 C CB    . LEU C 1 221 ? 154.697 138.129 97.319  1.00 34.83  ?  221 LEU D CB    1 
ATOM 5716 C CG    . LEU C 1 221 ? 154.756 139.219 98.385  1.00 34.83  ?  221 LEU D CG    1 
ATOM 5717 C CD1   . LEU C 1 221 ? 156.026 139.104 99.199  1.00 34.83  ?  221 LEU D CD1   1 
ATOM 5718 C CD2   . LEU C 1 221 ? 154.656 140.583 97.733  1.00 34.83  ?  221 LEU D CD2   1 
ATOM 5719 N N     . SER C 1 222 ? 153.621 136.053 95.196  1.00 33.87  ?  222 SER D N     1 
ATOM 5720 C CA    . SER C 1 222 ? 153.792 135.342 93.939  1.00 33.87  ?  222 SER D CA    1 
ATOM 5721 C C     . SER C 1 222 ? 153.203 133.947 94.071  1.00 33.87  ?  222 SER D C     1 
ATOM 5722 O O     . SER C 1 222 ? 153.022 133.429 95.175  1.00 33.87  ?  222 SER D O     1 
ATOM 5723 C CB    . SER C 1 222 ? 155.266 135.264 93.531  1.00 33.87  ?  222 SER D CB    1 
ATOM 5724 O OG    . SER C 1 222 ? 155.409 134.639 92.269  1.00 33.87  ?  222 SER D OG    1 
ATOM 5725 N N     . SER C 1 223 ? 152.909 133.340 92.923  1.00 34.04  ?  223 SER D N     1 
ATOM 5726 C CA    . SER C 1 223 ? 152.292 132.021 92.902  1.00 34.04  ?  223 SER D CA    1 
ATOM 5727 C C     . SER C 1 223 ? 153.306 130.889 92.968  1.00 34.04  ?  223 SER D C     1 
ATOM 5728 O O     . SER C 1 223 ? 152.987 129.816 93.493  1.00 34.04  ?  223 SER D O     1 
ATOM 5729 C CB    . SER C 1 223 ? 151.436 131.861 91.644  1.00 34.04  ?  223 SER D CB    1 
ATOM 5730 O OG    . SER C 1 223 ? 152.236 131.931 90.477  1.00 34.04  ?  223 SER D OG    1 
ATOM 5731 N N     . THR C 1 224 ? 154.514 131.096 92.456  1.00 32.34  ?  224 THR D N     1 
ATOM 5732 C CA    . THR C 1 224 ? 155.529 130.055 92.387  1.00 32.34  ?  224 THR D CA    1 
ATOM 5733 C C     . THR C 1 224 ? 156.635 130.342 93.391  1.00 32.34  ?  224 THR D C     1 
ATOM 5734 O O     . THR C 1 224 ? 157.159 131.459 93.441  1.00 32.34  ?  224 THR D O     1 
ATOM 5735 C CB    . THR C 1 224 ? 156.117 129.954 90.979  1.00 32.34  ?  224 THR D CB    1 
ATOM 5736 O OG1   . THR C 1 224 ? 157.007 131.053 90.754  1.00 32.34  ?  224 THR D OG1   1 
ATOM 5737 C CG2   . THR C 1 224 ? 155.009 129.986 89.941  1.00 32.34  ?  224 THR D CG2   1 
ATOM 5738 N N     . VAL C 1 225 ? 156.990 129.332 94.179  1.00 24.46  ?  225 VAL D N     1 
ATOM 5739 C CA    . VAL C 1 225 ? 158.051 129.427 95.173  1.00 24.46  ?  225 VAL D CA    1 
ATOM 5740 C C     . VAL C 1 225 ? 159.146 128.441 94.795  1.00 24.46  ?  225 VAL D C     1 
ATOM 5741 O O     . VAL C 1 225 ? 158.861 127.288 94.455  1.00 24.46  ?  225 VAL D O     1 
ATOM 5742 C CB    . VAL C 1 225 ? 157.525 129.157 96.594  1.00 24.46  ?  225 VAL D CB    1 
ATOM 5743 C CG1   . VAL C 1 225 ? 156.761 127.851 96.648  1.00 24.46  ?  225 VAL D CG1   1 
ATOM 5744 C CG2   . VAL C 1 225 ? 158.669 129.129 97.579  1.00 24.46  ?  225 VAL D CG2   1 
ATOM 5745 N N     . THR C 1 226 ? 160.392 128.900 94.832  1.00 25.39  ?  226 THR D N     1 
ATOM 5746 C CA    . THR C 1 226 ? 161.544 128.091 94.461  1.00 25.39  ?  226 THR D CA    1 
ATOM 5747 C C     . THR C 1 226 ? 162.322 127.708 95.711  1.00 25.39  ?  226 THR D C     1 
ATOM 5748 O O     . THR C 1 226 ? 162.654 128.571 96.529  1.00 25.39  ?  226 THR D O     1 
ATOM 5749 C CB    . THR C 1 226 ? 162.452 128.847 93.490  1.00 25.39  ?  226 THR D CB    1 
ATOM 5750 O OG1   . THR C 1 226 ? 161.712 129.194 92.314  1.00 25.39  ?  226 THR D OG1   1 
ATOM 5751 C CG2   . THR C 1 226 ? 163.641 127.991 93.099  1.00 25.39  ?  226 THR D CG2   1 
ATOM 5752 N N     . LEU C 1 227 ? 162.611 126.419 95.854  1.00 27.40  ?  227 LEU D N     1 
ATOM 5753 C CA    . LEU C 1 227 ? 163.393 125.901 96.968  1.00 27.40  ?  227 LEU D CA    1 
ATOM 5754 C C     . LEU C 1 227 ? 164.717 125.367 96.445  1.00 27.40  ?  227 LEU D C     1 
ATOM 5755 O O     . LEU C 1 227 ? 164.745 124.629 95.456  1.00 27.40  ?  227 LEU D O     1 
ATOM 5756 C CB    . LEU C 1 227 ? 162.638 124.796 97.707  1.00 27.40  ?  227 LEU D CB    1 
ATOM 5757 C CG    . LEU C 1 227 ? 161.525 125.235 98.654  1.00 27.40  ?  227 LEU D CG    1 
ATOM 5758 C CD1   . LEU C 1 227 ? 160.170 125.029 98.011  1.00 27.40  ?  227 LEU D CD1   1 
ATOM 5759 C CD2   . LEU C 1 227 ? 161.615 124.470 99.957  1.00 27.40  ?  227 LEU D CD2   1 
ATOM 5760 N N     . SER C 1 228 ? 165.808 125.743 97.105  1.00 36.92  ?  228 SER D N     1 
ATOM 5761 C CA    . SER C 1 228 ? 167.136 125.259 96.765  1.00 36.92  ?  228 SER D CA    1 
ATOM 5762 C C     . SER C 1 228 ? 167.866 124.881 98.042  1.00 36.92  ?  228 SER D C     1 
ATOM 5763 O O     . SER C 1 228 ? 167.777 125.590 99.048  1.00 36.92  ?  228 SER D O     1 
ATOM 5764 C CB    . SER C 1 228 ? 167.935 126.313 95.996  1.00 36.92  ?  228 SER D CB    1 
ATOM 5765 O OG    . SER C 1 228 ? 167.177 126.835 94.920  1.00 36.92  ?  228 SER D OG    1 
ATOM 5766 N N     . MET C 1 229 ? 168.587 123.764 98.001  1.00 43.34  ?  229 MET D N     1 
ATOM 5767 C CA    . MET C 1 229 ? 169.288 123.291 99.185  1.00 43.34  ?  229 MET D CA    1 
ATOM 5768 C C     . MET C 1 229 ? 170.408 122.351 98.771  1.00 43.34  ?  229 MET D C     1 
ATOM 5769 O O     . MET C 1 229 ? 170.441 121.848 97.645  1.00 43.34  ?  229 MET D O     1 
ATOM 5770 C CB    . MET C 1 229 ? 168.333 122.594 100.158 1.00 43.34  ?  229 MET D CB    1 
ATOM 5771 C CG    . MET C 1 229 ? 167.631 121.383 99.577  1.00 43.34  ?  229 MET D CG    1 
ATOM 5772 S SD    . MET C 1 229 ? 165.914 121.288 100.114 1.00 43.34  ?  229 MET D SD    1 
ATOM 5773 C CE    . MET C 1 229 ? 165.232 120.201 98.870  1.00 43.34  ?  229 MET D CE    1 
ATOM 5774 N N     . SER C 1 230 ? 171.325 122.125 99.706  1.00 52.76  ?  230 SER D N     1 
ATOM 5775 C CA    . SER C 1 230 ? 172.457 121.233 99.500  1.00 52.76  ?  230 SER D CA    1 
ATOM 5776 C C     . SER C 1 230 ? 172.874 120.676 100.857 1.00 52.76  ?  230 SER D C     1 
ATOM 5777 O O     . SER C 1 230 ? 172.155 120.815 101.851 1.00 52.76  ?  230 SER D O     1 
ATOM 5778 C CB    . SER C 1 230 ? 173.605 121.965 98.795  1.00 52.76  ?  230 SER D CB    1 
ATOM 5779 O OG    . SER C 1 230 ? 174.568 121.048 98.310  1.00 52.76  ?  230 SER D OG    1 
ATOM 5780 N N     . ALA C 1 231 ? 174.042 120.043 100.898 1.00 65.85  ?  231 ALA D N     1 
ATOM 5781 C CA    . ALA C 1 231 ? 174.539 119.441 102.129 1.00 65.85  ?  231 ALA D CA    1 
ATOM 5782 C C     . ALA C 1 231 ? 175.151 120.515 103.019 1.00 65.85  ?  231 ALA D C     1 
ATOM 5783 O O     . ALA C 1 231 ? 176.072 121.225 102.601 1.00 65.85  ?  231 ALA D O     1 
ATOM 5784 C CB    . ALA C 1 231 ? 175.564 118.355 101.813 1.00 65.85  ?  231 ALA D CB    1 
ATOM 5785 N N     . ASP C 1 232 ? 174.640 120.627 104.247 1.00 68.37  ?  232 ASP D N     1 
ATOM 5786 C CA    . ASP C 1 232 ? 175.147 121.578 105.240 1.00 68.37  ?  232 ASP D CA    1 
ATOM 5787 C C     . ASP C 1 232 ? 175.131 123.008 104.704 1.00 68.37  ?  232 ASP D C     1 
ATOM 5788 O O     . ASP C 1 232 ? 176.044 123.799 104.947 1.00 68.37  ?  232 ASP D O     1 
ATOM 5789 C CB    . ASP C 1 232 ? 176.548 121.185 105.708 1.00 68.37  ?  232 ASP D CB    1 
ATOM 5790 C CG    . ASP C 1 232 ? 176.639 119.727 106.108 1.00 68.37  ?  232 ASP D CG    1 
ATOM 5791 O OD1   . ASP C 1 232 ? 176.499 118.856 105.224 1.00 68.37  ?  232 ASP D OD1   1 
ATOM 5792 O OD2   . ASP C 1 232 ? 176.850 119.450 107.308 1.00 68.37  -1 232 ASP D OD2   1 
ATOM 5793 N N     . VAL C 1 233 ? 174.077 123.341 103.967 1.00 57.11  ?  233 VAL D N     1 
ATOM 5794 C CA    . VAL C 1 233 ? 173.892 124.683 103.424 1.00 57.11  ?  233 VAL D CA    1 
ATOM 5795 C C     . VAL C 1 233 ? 172.472 125.122 103.761 1.00 57.11  ?  233 VAL D C     1 
ATOM 5796 O O     . VAL C 1 233 ? 171.536 124.319 103.639 1.00 57.11  ?  233 VAL D O     1 
ATOM 5797 C CB    . VAL C 1 233 ? 174.158 124.712 101.910 1.00 57.11  ?  233 VAL D CB    1 
ATOM 5798 C CG1   . VAL C 1 233 ? 173.621 125.991 101.288 1.00 57.11  ?  233 VAL D CG1   1 
ATOM 5799 C CG2   . VAL C 1 233 ? 175.646 124.568 101.633 1.00 57.11  ?  233 VAL D CG2   1 
ATOM 5800 N N     . PRO C 1 234 ? 172.264 126.361 104.204 1.00 44.13  ?  234 PRO D N     1 
ATOM 5801 C CA    . PRO C 1 234 ? 170.911 126.789 104.579 1.00 44.13  ?  234 PRO D CA    1 
ATOM 5802 C C     . PRO C 1 234 ? 169.943 126.702 103.408 1.00 44.13  ?  234 PRO D C     1 
ATOM 5803 O O     . PRO C 1 234 ? 170.305 126.945 102.256 1.00 44.13  ?  234 PRO D O     1 
ATOM 5804 C CB    . PRO C 1 234 ? 171.111 128.238 105.035 1.00 44.13  ?  234 PRO D CB    1 
ATOM 5805 C CG    . PRO C 1 234 ? 172.541 128.315 105.434 1.00 44.13  ?  234 PRO D CG    1 
ATOM 5806 C CD    . PRO C 1 234 ? 173.276 127.381 104.523 1.00 44.13  ?  234 PRO D CD    1 
ATOM 5807 N N     . LEU C 1 235 ? 168.703 126.338 103.720 1.00 37.81  ?  235 LEU D N     1 
ATOM 5808 C CA    . LEU C 1 235 ? 167.660 126.270 102.709 1.00 37.81  ?  235 LEU D CA    1 
ATOM 5809 C C     . LEU C 1 235 ? 167.326 127.666 102.200 1.00 37.81  ?  235 LEU D C     1 
ATOM 5810 O O     . LEU C 1 235 ? 167.294 128.631 102.966 1.00 37.81  ?  235 LEU D O     1 
ATOM 5811 C CB    . LEU C 1 235 ? 166.413 125.605 103.288 1.00 37.81  ?  235 LEU D CB    1 
ATOM 5812 C CG    . LEU C 1 235 ? 165.101 125.735 102.517 1.00 37.81  ?  235 LEU D CG    1 
ATOM 5813 C CD1   . LEU C 1 235 ? 164.991 124.632 101.483 1.00 37.81  ?  235 LEU D CD1   1 
ATOM 5814 C CD2   . LEU C 1 235 ? 163.922 125.698 103.468 1.00 37.81  ?  235 LEU D CD2   1 
ATOM 5815 N N     . VAL C 1 236 ? 167.077 127.771 100.898 1.00 35.23  ?  236 VAL D N     1 
ATOM 5816 C CA    . VAL C 1 236 ? 166.767 129.042 100.254 1.00 35.23  ?  236 VAL D CA    1 
ATOM 5817 C C     . VAL C 1 236 ? 165.332 128.981 99.754  1.00 35.23  ?  236 VAL D C     1 
ATOM 5818 O O     . VAL C 1 236 ? 164.980 128.102 98.957  1.00 35.23  ?  236 VAL D O     1 
ATOM 5819 C CB    . VAL C 1 236 ? 167.741 129.347 99.107  1.00 35.23  ?  236 VAL D CB    1 
ATOM 5820 C CG1   . VAL C 1 236 ? 167.098 130.277 98.094  1.00 35.23  ?  236 VAL D CG1   1 
ATOM 5821 C CG2   . VAL C 1 236 ? 169.019 129.954 99.651  1.00 35.23  ?  236 VAL D CG2   1 
ATOM 5822 N N     . VAL C 1 237 ? 164.505 129.908 100.224 1.00 54.26  ?  237 VAL D N     1 
ATOM 5823 C CA    . VAL C 1 237 ? 163.121 130.040 99.788  1.00 54.26  ?  237 VAL D CA    1 
ATOM 5824 C C     . VAL C 1 237 ? 162.984 131.403 99.131  1.00 54.26  ?  237 VAL D C     1 
ATOM 5825 O O     . VAL C 1 237 ? 163.129 132.434 99.798  1.00 54.26  ?  237 VAL D O     1 
ATOM 5826 C CB    . VAL C 1 237 ? 162.138 129.892 100.958 1.00 54.26  ?  237 VAL D CB    1 
ATOM 5827 C CG1   . VAL C 1 237 ? 160.715 129.970 100.462 1.00 54.26  ?  237 VAL D CG1   1 
ATOM 5828 C CG2   . VAL C 1 237 ? 162.377 128.586 101.684 1.00 54.26  ?  237 VAL D CG2   1 
ATOM 5829 N N     . GLU C 1 238 ? 162.702 131.413 97.832  1.00 35.04  ?  238 GLU D N     1 
ATOM 5830 C CA    . GLU C 1 238 ? 162.736 132.631 97.036  1.00 35.04  ?  238 GLU D CA    1 
ATOM 5831 C C     . GLU C 1 238 ? 161.360 132.922 96.458  1.00 35.04  ?  238 GLU D C     1 
ATOM 5832 O O     . GLU C 1 238 ? 160.726 132.037 95.877  1.00 35.04  ?  238 GLU D O     1 
ATOM 5833 C CB    . GLU C 1 238 ? 163.766 132.514 95.912  1.00 35.04  ?  238 GLU D CB    1 
ATOM 5834 C CG    . GLU C 1 238 ? 163.487 133.404 94.720  1.00 35.04  ?  238 GLU D CG    1 
ATOM 5835 C CD    . GLU C 1 238 ? 164.665 133.487 93.775  1.00 35.04  ?  238 GLU D CD    1 
ATOM 5836 O OE1   . GLU C 1 238 ? 165.724 132.907 94.095  1.00 35.04  ?  238 GLU D OE1   1 
ATOM 5837 O OE2   . GLU C 1 238 ? 164.536 134.134 92.715  1.00 35.04  -1 238 GLU D OE2   1 
ATOM 5838 N N     . TYR C 1 239 ? 160.907 134.162 96.617  1.00 30.29  ?  239 TYR D N     1 
ATOM 5839 C CA    . TYR C 1 239 ? 159.664 134.641 96.029  1.00 30.29  ?  239 TYR D CA    1 
ATOM 5840 C C     . TYR C 1 239 ? 159.987 135.763 95.056  1.00 30.29  ?  239 TYR D C     1 
ATOM 5841 O O     . TYR C 1 239 ? 160.748 136.676 95.389  1.00 30.29  ?  239 TYR D O     1 
ATOM 5842 C CB    . TYR C 1 239 ? 158.697 135.143 97.102  1.00 30.29  ?  239 TYR D CB    1 
ATOM 5843 C CG    . TYR C 1 239 ? 158.039 134.054 97.912  1.00 30.29  ?  239 TYR D CG    1 
ATOM 5844 C CD1   . TYR C 1 239 ? 158.774 133.273 98.787  1.00 30.29  ?  239 TYR D CD1   1 
ATOM 5845 C CD2   . TYR C 1 239 ? 156.678 133.816 97.808  1.00 30.29  ?  239 TYR D CD2   1 
ATOM 5846 C CE1   . TYR C 1 239 ? 158.174 132.282 99.531  1.00 30.29  ?  239 TYR D CE1   1 
ATOM 5847 C CE2   . TYR C 1 239 ? 156.070 132.827 98.548  1.00 30.29  ?  239 TYR D CE2   1 
ATOM 5848 C CZ    . TYR C 1 239 ? 156.823 132.063 99.407  1.00 30.29  ?  239 TYR D CZ    1 
ATOM 5849 O OH    . TYR C 1 239 ? 156.221 131.074 100.148 1.00 30.29  ?  239 TYR D OH    1 
ATOM 5850 N N     . LYS C 1 240 ? 159.409 135.700 93.861  1.00 33.45  ?  240 LYS D N     1 
ATOM 5851 C CA    . LYS C 1 240 ? 159.628 136.721 92.845  1.00 33.45  ?  240 LYS D CA    1 
ATOM 5852 C C     . LYS C 1 240 ? 158.623 137.848 93.044  1.00 33.45  ?  240 LYS D C     1 
ATOM 5853 O O     . LYS C 1 240 ? 157.411 137.609 93.059  1.00 33.45  ?  240 LYS D O     1 
ATOM 5854 C CB    . LYS C 1 240 ? 159.504 136.127 91.445  1.00 33.45  ?  240 LYS D CB    1 
ATOM 5855 C CG    . LYS C 1 240 ? 160.578 136.595 90.483  1.00 33.45  ?  240 LYS D CG    1 
ATOM 5856 C CD    . LYS C 1 240 ? 161.962 136.261 91.008  1.00 33.45  ?  240 LYS D CD    1 
ATOM 5857 C CE    . LYS C 1 240 ? 162.965 136.130 89.876  1.00 33.45  ?  240 LYS D CE    1 
ATOM 5858 N NZ    . LYS C 1 240 ? 164.357 135.996 90.386  1.00 33.45  1  240 LYS D NZ    1 
ATOM 5859 N N     . ILE C 1 241 ? 159.122 139.072 93.192  1.00 40.84  ?  241 ILE D N     1 
ATOM 5860 C CA    . ILE C 1 241 ? 158.252 140.234 93.444  1.00 40.84  ?  241 ILE D CA    1 
ATOM 5861 C C     . ILE C 1 241 ? 157.876 140.783 92.074  1.00 40.84  ?  241 ILE D C     1 
ATOM 5862 O O     . ILE C 1 241 ? 158.472 141.729 91.551  1.00 40.84  ?  241 ILE D O     1 
ATOM 5863 C CB    . ILE C 1 241 ? 158.928 141.278 94.336  1.00 40.84  ?  241 ILE D CB    1 
ATOM 5864 C CG1   . ILE C 1 241 ? 159.282 140.670 95.688  1.00 40.84  ?  241 ILE D CG1   1 
ATOM 5865 C CG2   . ILE C 1 241 ? 158.005 142.462 94.552  1.00 40.84  ?  241 ILE D CG2   1 
ATOM 5866 C CD1   . ILE C 1 241 ? 158.080 140.263 96.490  1.00 40.84  ?  241 ILE D CD1   1 
ATOM 5867 N N     . ALA C 1 242 ? 156.845 140.177 91.481  1.00 46.09  ?  242 ALA D N     1 
ATOM 5868 C CA    . ALA C 1 242 ? 156.360 140.554 90.157  1.00 46.09  ?  242 ALA D CA    1 
ATOM 5869 C C     . ALA C 1 242 ? 157.508 140.671 89.164  1.00 46.09  ?  242 ALA D C     1 
ATOM 5870 O O     . ALA C 1 242 ? 158.195 139.686 88.876  1.00 46.09  ?  242 ALA D O     1 
ATOM 5871 C CB    . ALA C 1 242 ? 155.579 141.868 90.226  1.00 46.09  ?  242 ALA D CB    1 
ATOM 5872 N N     . ASP C 1 243 ? 157.721 141.875 88.637  1.00 52.99  ?  243 ASP D N     1 
ATOM 5873 C CA    . ASP C 1 243 ? 158.863 142.169 87.783  1.00 52.99  ?  243 ASP D CA    1 
ATOM 5874 C C     . ASP C 1 243 ? 159.822 143.160 88.428  1.00 52.99  ?  243 ASP D C     1 
ATOM 5875 O O     . ASP C 1 243 ? 160.753 143.630 87.765  1.00 52.99  ?  243 ASP D O     1 
ATOM 5876 C CB    . ASP C 1 243 ? 158.387 142.703 86.432  1.00 52.99  ?  243 ASP D CB    1 
ATOM 5877 C CG    . ASP C 1 243 ? 157.253 143.699 86.568  1.00 52.99  ?  243 ASP D CG    1 
ATOM 5878 O OD1   . ASP C 1 243 ? 156.493 143.603 87.554  1.00 52.99  ?  243 ASP D OD1   1 
ATOM 5879 O OD2   . ASP C 1 243 ? 157.123 144.578 85.691  1.00 52.99  -1 243 ASP D OD2   1 
ATOM 5880 N N     . MET C 1 244 ? 159.619 143.489 89.703  1.00 52.00  ?  244 MET D N     1 
ATOM 5881 C CA    . MET C 1 244 ? 160.437 144.485 90.381  1.00 52.00  ?  244 MET D CA    1 
ATOM 5882 C C     . MET C 1 244 ? 161.696 143.876 90.987  1.00 52.00  ?  244 MET D C     1 
ATOM 5883 O O     . MET C 1 244 ? 162.801 144.379 90.765  1.00 52.00  ?  244 MET D O     1 
ATOM 5884 C CB    . MET C 1 244 ? 159.616 145.184 91.467  1.00 52.00  ?  244 MET D CB    1 
ATOM 5885 C CG    . MET C 1 244 ? 158.898 146.426 90.983  1.00 52.00  ?  244 MET D CG    1 
ATOM 5886 S SD    . MET C 1 244 ? 158.007 147.309 92.276  1.00 52.00  ?  244 MET D SD    1 
ATOM 5887 C CE    . MET C 1 244 ? 157.799 146.014 93.489  1.00 52.00  ?  244 MET D CE    1 
ATOM 5888 N N     . GLY C 1 245 ? 161.546 142.800 91.752  1.00 42.59  ?  245 GLY D N     1 
ATOM 5889 C CA    . GLY C 1 245 ? 162.682 142.167 92.390  1.00 42.59  ?  245 GLY D CA    1 
ATOM 5890 C C     . GLY C 1 245 ? 162.347 140.814 92.978  1.00 42.59  ?  245 GLY D C     1 
ATOM 5891 O O     . GLY C 1 245 ? 161.468 140.112 92.471  1.00 42.59  ?  245 GLY D O     1 
ATOM 5892 N N     . HIS C 1 246 ? 163.035 140.438 94.052  1.00 35.56  ?  246 HIS D N     1 
ATOM 5893 C CA    . HIS C 1 246 ? 162.824 139.138 94.667  1.00 35.56  ?  246 HIS D CA    1 
ATOM 5894 C C     . HIS C 1 246 ? 162.974 139.267 96.173  1.00 35.56  ?  246 HIS D C     1 
ATOM 5895 O O     . HIS C 1 246 ? 163.590 140.209 96.678  1.00 35.56  ?  246 HIS D O     1 
ATOM 5896 C CB    . HIS C 1 246 ? 163.799 138.093 94.121  1.00 35.56  ?  246 HIS D CB    1 
ATOM 5897 C CG    . HIS C 1 246 ? 165.237 138.429 94.359  1.00 35.56  ?  246 HIS D CG    1 
ATOM 5898 N ND1   . HIS C 1 246 ? 165.862 138.205 95.566  1.00 35.56  ?  246 HIS D ND1   1 
ATOM 5899 C CD2   . HIS C 1 246 ? 166.172 138.972 93.545  1.00 35.56  ?  246 HIS D CD2   1 
ATOM 5900 C CE1   . HIS C 1 246 ? 167.122 138.595 95.485  1.00 35.56  ?  246 HIS D CE1   1 
ATOM 5901 N NE2   . HIS C 1 246 ? 167.335 139.065 94.270  1.00 35.56  ?  246 HIS D NE2   1 
ATOM 5902 N N     . LEU C 1 247 ? 162.403 138.301 96.887  1.00 25.69  ?  247 LEU D N     1 
ATOM 5903 C CA    . LEU C 1 247 ? 162.402 138.285 98.345  1.00 25.69  ?  247 LEU D CA    1 
ATOM 5904 C C     . LEU C 1 247 ? 162.849 136.906 98.808  1.00 25.69  ?  247 LEU D C     1 
ATOM 5905 O O     . LEU C 1 247 ? 162.076 135.946 98.737  1.00 25.69  ?  247 LEU D O     1 
ATOM 5906 C CB    . LEU C 1 247 ? 161.017 138.627 98.888  1.00 25.69  ?  247 LEU D CB    1 
ATOM 5907 C CG    . LEU C 1 247 ? 160.784 138.445 100.384 1.00 25.69  ?  247 LEU D CG    1 
ATOM 5908 C CD1   . LEU C 1 247 ? 161.426 139.570 101.165 1.00 25.69  ?  247 LEU D CD1   1 
ATOM 5909 C CD2   . LEU C 1 247 ? 159.300 138.374 100.679 1.00 25.69  ?  247 LEU D CD2   1 
ATOM 5910 N N     . LYS C 1 248 ? 164.086 136.807 99.282  1.00 35.39  ?  248 LYS D N     1 
ATOM 5911 C CA    . LYS C 1 248 ? 164.685 135.533 99.653  1.00 35.39  ?  248 LYS D CA    1 
ATOM 5912 C C     . LYS C 1 248 ? 164.603 135.316 101.157 1.00 35.39  ?  248 LYS D C     1 
ATOM 5913 O O     . LYS C 1 248 ? 164.779 136.250 101.941 1.00 35.39  ?  248 LYS D O     1 
ATOM 5914 C CB    . LYS C 1 248 ? 166.146 135.467 99.209  1.00 35.39  ?  248 LYS D CB    1 
ATOM 5915 C CG    . LYS C 1 248 ? 166.340 135.460 97.710  1.00 35.39  ?  248 LYS D CG    1 
ATOM 5916 C CD    . LYS C 1 248 ? 167.803 135.288 97.357  1.00 35.39  ?  248 LYS D CD    1 
ATOM 5917 C CE    . LYS C 1 248 ? 167.998 135.207 95.855  1.00 35.39  ?  248 LYS D CE    1 
ATOM 5918 N NZ    . LYS C 1 248 ? 169.420 134.957 95.496  1.00 35.39  1  248 LYS D NZ    1 
ATOM 5919 N N     . TYR C 1 249 ? 164.334 134.075 101.549 1.00 26.79  ?  249 TYR D N     1 
ATOM 5920 C CA    . TYR C 1 249 ? 164.322 133.664 102.946 1.00 26.79  ?  249 TYR D CA    1 
ATOM 5921 C C     . TYR C 1 249 ? 165.378 132.588 103.138 1.00 26.79  ?  249 TYR D C     1 
ATOM 5922 O O     . TYR C 1 249 ? 165.509 131.688 102.303 1.00 26.79  ?  249 TYR D O     1 
ATOM 5923 C CB    . TYR C 1 249 ? 162.951 133.127 103.361 1.00 26.79  ?  249 TYR D CB    1 
ATOM 5924 C CG    . TYR C 1 249 ? 161.891 134.178 103.599 1.00 26.79  ?  249 TYR D CG    1 
ATOM 5925 C CD1   . TYR C 1 249 ? 161.774 135.282 102.775 1.00 26.79  ?  249 TYR D CD1   1 
ATOM 5926 C CD2   . TYR C 1 249 ? 160.997 134.054 104.646 1.00 26.79  ?  249 TYR D CD2   1 
ATOM 5927 C CE1   . TYR C 1 249 ? 160.804 136.232 102.996 1.00 26.79  ?  249 TYR D CE1   1 
ATOM 5928 C CE2   . TYR C 1 249 ? 160.024 134.998 104.875 1.00 26.79  ?  249 TYR D CE2   1 
ATOM 5929 C CZ    . TYR C 1 249 ? 159.931 136.086 104.046 1.00 26.79  ?  249 TYR D CZ    1 
ATOM 5930 O OH    . TYR C 1 249 ? 158.960 137.034 104.268 1.00 26.79  ?  249 TYR D OH    1 
ATOM 5931 N N     . TYR C 1 250 ? 166.131 132.679 104.228 1.00 38.87  ?  250 TYR D N     1 
ATOM 5932 C CA    . TYR C 1 250 ? 167.180 131.719 104.532 1.00 38.87  ?  250 TYR D CA    1 
ATOM 5933 C C     . TYR C 1 250 ? 166.862 131.013 105.841 1.00 38.87  ?  250 TYR D C     1 
ATOM 5934 O O     . TYR C 1 250 ? 166.188 131.566 106.714 1.00 38.87  ?  250 TYR D O     1 
ATOM 5935 C CB    . TYR C 1 250 ? 168.554 132.392 104.632 1.00 38.87  ?  250 TYR D CB    1 
ATOM 5936 C CG    . TYR C 1 250 ? 169.203 132.719 103.305 1.00 38.87  ?  250 TYR D CG    1 
ATOM 5937 C CD1   . TYR C 1 250 ? 168.444 133.091 102.207 1.00 38.87  ?  250 TYR D CD1   1 
ATOM 5938 C CD2   . TYR C 1 250 ? 170.579 132.659 103.155 1.00 38.87  ?  250 TYR D CD2   1 
ATOM 5939 C CE1   . TYR C 1 250 ? 169.035 133.391 100.999 1.00 38.87  ?  250 TYR D CE1   1 
ATOM 5940 C CE2   . TYR C 1 250 ? 171.179 132.957 101.952 1.00 38.87  ?  250 TYR D CE2   1 
ATOM 5941 C CZ    . TYR C 1 250 ? 170.403 133.322 100.877 1.00 38.87  ?  250 TYR D CZ    1 
ATOM 5942 O OH    . TYR C 1 250 ? 170.996 133.621 99.673  1.00 38.87  ?  250 TYR D OH    1 
ATOM 5943 N N     . LEU C 1 251 ? 167.350 129.782 105.972 1.00 34.35  ?  251 LEU D N     1 
ATOM 5944 C CA    . LEU C 1 251 ? 167.131 129.004 107.188 1.00 34.35  ?  251 LEU D CA    1 
ATOM 5945 C C     . LEU C 1 251 ? 168.186 127.916 107.265 1.00 34.35  ?  251 LEU D C     1 
ATOM 5946 O O     . LEU C 1 251 ? 168.271 127.075 106.366 1.00 34.35  ?  251 LEU D O     1 
ATOM 5947 C CB    . LEU C 1 251 ? 165.731 128.396 107.205 1.00 34.35  ?  251 LEU D CB    1 
ATOM 5948 C CG    . LEU C 1 251 ? 165.461 127.381 108.316 1.00 34.35  ?  251 LEU D CG    1 
ATOM 5949 C CD1   . LEU C 1 251 ? 165.614 128.026 109.679 1.00 34.35  ?  251 LEU D CD1   1 
ATOM 5950 C CD2   . LEU C 1 251 ? 164.079 126.780 108.164 1.00 34.35  ?  251 LEU D CD2   1 
ATOM 5951 N N     . ALA C 1 252 ? 168.982 127.931 108.329 1.00 39.25  ?  252 ALA D N     1 
ATOM 5952 C CA    . ALA C 1 252 ? 169.982 126.894 108.516 1.00 39.25  ?  252 ALA D CA    1 
ATOM 5953 C C     . ALA C 1 252 ? 169.307 125.578 108.897 1.00 39.25  ?  252 ALA D C     1 
ATOM 5954 O O     . ALA C 1 252 ? 168.385 125.568 109.718 1.00 39.25  ?  252 ALA D O     1 
ATOM 5955 C CB    . ALA C 1 252 ? 170.984 127.298 109.596 1.00 39.25  ?  252 ALA D CB    1 
ATOM 5956 N N     . PRO C 1 253 ? 169.737 124.460 108.320 1.00 45.66  ?  253 PRO D N     1 
ATOM 5957 C CA    . PRO C 1 253 ? 169.106 123.178 108.643 1.00 45.66  ?  253 PRO D CA    1 
ATOM 5958 C C     . PRO C 1 253 ? 169.349 122.783 110.089 1.00 45.66  ?  253 PRO D C     1 
ATOM 5959 O O     . PRO C 1 253 ? 170.359 123.143 110.697 1.00 45.66  ?  253 PRO D O     1 
ATOM 5960 C CB    . PRO C 1 253 ? 169.782 122.198 107.679 1.00 45.66  ?  253 PRO D CB    1 
ATOM 5961 C CG    . PRO C 1 253 ? 171.095 122.821 107.373 1.00 45.66  ?  253 PRO D CG    1 
ATOM 5962 C CD    . PRO C 1 253 ? 170.866 124.305 107.389 1.00 45.66  ?  253 PRO D CD    1 
ATOM 5963 N N     . LYS C 1 254 ? 168.396 122.035 110.638 1.00 57.07  ?  254 LYS D N     1 
ATOM 5964 C CA    . LYS C 1 254 ? 168.535 121.529 111.995 1.00 57.07  ?  254 LYS D CA    1 
ATOM 5965 C C     . LYS C 1 254 ? 169.700 120.551 112.080 1.00 57.07  ?  254 LYS D C     1 
ATOM 5966 O O     . LYS C 1 254 ? 170.011 119.833 111.126 1.00 57.07  ?  254 LYS D O     1 
ATOM 5967 C CB    . LYS C 1 254 ? 167.247 120.842 112.444 1.00 57.07  ?  254 LYS D CB    1 
ATOM 5968 C CG    . LYS C 1 254 ? 166.451 121.613 113.479 1.00 57.07  ?  254 LYS D CG    1 
ATOM 5969 C CD    . LYS C 1 254 ? 165.387 120.729 114.108 1.00 57.07  ?  254 LYS D CD    1 
ATOM 5970 C CE    . LYS C 1 254 ? 164.855 121.332 115.396 1.00 57.07  ?  254 LYS D CE    1 
ATOM 5971 N NZ    . LYS C 1 254 ? 163.870 120.434 116.059 1.00 57.07  1  254 LYS D NZ    1 
ATOM 5972 N N     . ILE C 1 255 ? 170.349 120.531 113.237 1.00 82.62  ?  255 ILE D N     1 
ATOM 5973 C CA    . ILE C 1 255 ? 171.459 119.621 113.489 1.00 82.62  ?  255 ILE D CA    1 
ATOM 5974 C C     . ILE C 1 255 ? 170.889 118.308 114.005 1.00 82.62  ?  255 ILE D C     1 
ATOM 5975 O O     . ILE C 1 255 ? 170.303 118.259 115.092 1.00 82.62  ?  255 ILE D O     1 
ATOM 5976 C CB    . ILE C 1 255 ? 172.458 120.222 114.488 1.00 82.62  ?  255 ILE D CB    1 
ATOM 5977 C CG1   . ILE C 1 255 ? 172.966 121.573 113.981 1.00 82.62  ?  255 ILE D CG1   1 
ATOM 5978 C CG2   . ILE C 1 255 ? 173.617 119.267 114.719 1.00 82.62  ?  255 ILE D CG2   1 
ATOM 5979 C CD1   . ILE C 1 255 ? 173.807 122.325 114.986 1.00 82.62  ?  255 ILE D CD1   1 
ATOM 5980 N N     . GLU C 1 256 ? 171.059 117.243 113.225 1.00 109.61 ?  256 GLU D N     1 
ATOM 5981 C CA    . GLU C 1 256 ? 170.526 115.936 113.593 1.00 109.61 ?  256 GLU D CA    1 
ATOM 5982 C C     . GLU C 1 256 ? 171.359 115.351 114.726 1.00 109.61 ?  256 GLU D C     1 
ATOM 5983 O O     . GLU C 1 256 ? 172.522 114.985 114.529 1.00 109.61 ?  256 GLU D O     1 
ATOM 5984 C CB    . GLU C 1 256 ? 170.517 115.009 112.381 1.00 109.61 ?  256 GLU D CB    1 
ATOM 5985 C CG    . GLU C 1 256 ? 169.190 114.978 111.638 1.00 109.61 ?  256 GLU D CG    1 
ATOM 5986 C CD    . GLU C 1 256 ? 169.220 114.070 110.424 1.00 109.61 ?  256 GLU D CD    1 
ATOM 5987 O OE1   . GLU C 1 256 ? 170.308 113.553 110.094 1.00 109.61 ?  256 GLU D OE1   1 
ATOM 5988 O OE2   . GLU C 1 256 ? 168.156 113.873 109.801 1.00 109.61 -1 256 GLU D OE2   1 
ATOM 5989 N N     . ASP C 1 257 ? 170.766 115.265 115.912 1.00 137.91 ?  257 ASP D N     1 
ATOM 5990 C CA    . ASP C 1 257 ? 171.463 114.720 117.065 1.00 137.91 ?  257 ASP D CA    1 
ATOM 5991 C C     . ASP C 1 257 ? 171.613 113.207 116.935 1.00 137.91 ?  257 ASP D C     1 
ATOM 5992 O O     . ASP C 1 257 ? 170.939 112.552 116.134 1.00 137.91 ?  257 ASP D O     1 
ATOM 5993 C CB    . ASP C 1 257 ? 170.717 115.066 118.354 1.00 137.91 ?  257 ASP D CB    1 
ATOM 5994 C CG    . ASP C 1 257 ? 170.965 116.490 118.806 1.00 137.91 ?  257 ASP D CG    1 
ATOM 5995 O OD1   . ASP C 1 257 ? 171.998 117.070 118.408 1.00 137.91 ?  257 ASP D OD1   1 
ATOM 5996 O OD2   . ASP C 1 257 ? 170.127 117.031 119.557 1.00 137.91 -1 257 ASP D OD2   1 
ATOM 5997 N N     . GLU C 1 258 ? 172.516 112.651 117.742 1.00 147.98 ?  258 GLU D N     1 
ATOM 5998 C CA    . GLU C 1 258 ? 172.769 111.211 117.753 1.00 147.98 ?  258 GLU D CA    1 
ATOM 5999 C C     . GLU C 1 258 ? 171.683 110.485 118.553 1.00 147.98 ?  258 GLU D C     1 
ATOM 6000 O O     . GLU C 1 258 ? 171.935 109.825 119.561 1.00 147.98 ?  258 GLU D O     1 
ATOM 6001 C CB    . GLU C 1 258 ? 174.157 110.926 118.311 1.00 147.98 ?  258 GLU D CB    1 
ATOM 6002 C CG    . GLU C 1 258 ? 175.242 110.826 117.251 1.00 147.98 ?  258 GLU D CG    1 
ATOM 6003 C CD    . GLU C 1 258 ? 176.608 110.535 117.840 1.00 147.98 ?  258 GLU D CD    1 
ATOM 6004 O OE1   . GLU C 1 258 ? 176.714 110.442 119.081 1.00 147.98 ?  258 GLU D OE1   1 
ATOM 6005 O OE2   . GLU C 1 258 ? 177.576 110.400 117.063 1.00 147.98 -1 258 GLU D OE2   1 
ATOM 6006 N N     . GLU C 1 259 ? 170.445 110.625 118.074 1.00 149.98 ?  259 GLU D N     1 
ATOM 6007 C CA    . GLU C 1 259 ? 169.308 110.004 118.740 1.00 149.98 ?  259 GLU D CA    1 
ATOM 6008 C C     . GLU C 1 259 ? 169.252 108.499 118.513 1.00 149.98 ?  259 GLU D C     1 
ATOM 6009 O O     . GLU C 1 259 ? 168.667 107.784 119.333 1.00 149.98 ?  259 GLU D O     1 
ATOM 6010 C CB    . GLU C 1 259 ? 168.007 110.653 118.267 1.00 149.98 ?  259 GLU D CB    1 
ATOM 6011 C CG    . GLU C 1 259 ? 167.585 111.861 119.087 1.00 149.98 ?  259 GLU D CG    1 
ATOM 6012 C CD    . GLU C 1 259 ? 166.430 112.617 118.461 1.00 149.98 ?  259 GLU D CD    1 
ATOM 6013 O OE1   . GLU C 1 259 ? 166.032 112.267 117.330 1.00 149.98 ?  259 GLU D OE1   1 
ATOM 6014 O OE2   . GLU C 1 259 ? 165.921 113.563 119.099 1.00 149.98 -1 259 GLU D OE2   1 
ATOM 6015 N N     . GLY C 1 260 ? 169.840 108.007 117.421 1.00 145.71 ?  260 GLY D N     1 
ATOM 6016 C CA    . GLY C 1 260 ? 169.837 106.574 117.174 1.00 145.71 ?  260 GLY D CA    1 
ATOM 6017 C C     . GLY C 1 260 ? 170.638 105.799 118.202 1.00 145.71 ?  260 GLY D C     1 
ATOM 6018 O O     . GLY C 1 260 ? 170.271 104.681 118.574 1.00 145.71 ?  260 GLY D O     1 
ATOM 6019 N N     . SER C 1 261 ? 171.739 106.376 118.673 1.00 148.57 ?  261 SER D N     1 
ATOM 6020 C CA    . SER C 1 261 ? 172.584 105.724 119.666 1.00 148.57 ?  261 SER D CA    1 
ATOM 6021 C C     . SER C 1 261 ? 171.891 105.662 121.023 1.00 148.57 ?  261 SER D C     1 
ATOM 6022 O O     . SER C 1 261 ? 170.960 106.422 121.291 1.00 148.57 ?  261 SER D O     1 
ATOM 6023 C CB    . SER C 1 261 ? 173.924 106.453 119.792 1.00 148.57 ?  261 SER D CB    1 
ATOM 6024 O OG    . SER C 1 261 ? 174.351 106.956 118.539 1.00 148.57 ?  261 SER D OG    1 
ATOM 6025 N N     . HIS D 2 1   ? 163.099 119.636 172.686 1.00 126.49 ?  372 HIS E N     1 
ATOM 6026 C CA    . HIS D 2 1   ? 161.686 119.627 172.328 1.00 126.49 ?  372 HIS E CA    1 
ATOM 6027 C C     . HIS D 2 1   ? 161.322 120.941 171.641 1.00 126.49 ?  372 HIS E C     1 
ATOM 6028 O O     . HIS D 2 1   ? 161.720 122.012 172.100 1.00 126.49 ?  372 HIS E O     1 
ATOM 6029 C CB    . HIS D 2 1   ? 160.812 119.413 173.567 1.00 126.49 ?  372 HIS E CB    1 
ATOM 6030 C CG    . HIS D 2 1   ? 161.043 118.104 174.260 1.00 126.49 ?  372 HIS E CG    1 
ATOM 6031 N ND1   . HIS D 2 1   ? 162.291 117.529 174.374 1.00 126.49 ?  372 HIS E ND1   1 
ATOM 6032 C CD2   . HIS D 2 1   ? 160.185 117.263 174.886 1.00 126.49 ?  372 HIS E CD2   1 
ATOM 6033 C CE1   . HIS D 2 1   ? 162.191 116.390 175.035 1.00 126.49 ?  372 HIS E CE1   1 
ATOM 6034 N NE2   . HIS D 2 1   ? 160.924 116.205 175.357 1.00 126.49 ?  372 HIS E NE2   1 
ATOM 6035 N N     . PRO D 2 2   ? 160.573 120.867 170.543 1.00 128.05 ?  373 PRO E N     1 
ATOM 6036 C CA    . PRO D 2 2   ? 160.168 122.093 169.846 1.00 128.05 ?  373 PRO E CA    1 
ATOM 6037 C C     . PRO D 2 2   ? 159.228 122.930 170.698 1.00 128.05 ?  373 PRO E C     1 
ATOM 6038 O O     . PRO D 2 2   ? 158.433 122.410 171.480 1.00 128.05 ?  373 PRO E O     1 
ATOM 6039 C CB    . PRO D 2 2   ? 159.474 121.574 168.585 1.00 128.05 ?  373 PRO E CB    1 
ATOM 6040 C CG    . PRO D 2 2   ? 159.007 120.204 168.945 1.00 128.05 ?  373 PRO E CG    1 
ATOM 6041 C CD    . PRO D 2 2   ? 160.005 119.656 169.924 1.00 128.05 ?  373 PRO E CD    1 
ATOM 6042 N N     . TYR D 2 3   ? 159.316 124.252 170.511 1.00 130.34 ?  374 TYR E N     1 
ATOM 6043 C CA    . TYR D 2 3   ? 158.746 125.193 171.475 1.00 130.34 ?  374 TYR E CA    1 
ATOM 6044 C C     . TYR D 2 3   ? 157.268 124.929 171.728 1.00 130.34 ?  374 TYR E C     1 
ATOM 6045 O O     . TYR D 2 3   ? 156.806 125.008 172.872 1.00 130.34 ?  374 TYR E O     1 
ATOM 6046 C CB    . TYR D 2 3   ? 158.949 126.631 170.994 1.00 130.34 ?  374 TYR E CB    1 
ATOM 6047 C CG    . TYR D 2 3   ? 158.227 126.966 169.710 1.00 130.34 ?  374 TYR E CG    1 
ATOM 6048 C CD1   . TYR D 2 3   ? 158.766 126.624 168.481 1.00 130.34 ?  374 TYR E CD1   1 
ATOM 6049 C CD2   . TYR D 2 3   ? 156.994 127.605 169.730 1.00 130.34 ?  374 TYR E CD2   1 
ATOM 6050 C CE1   . TYR D 2 3   ? 158.110 126.931 167.303 1.00 130.34 ?  374 TYR E CE1   1 
ATOM 6051 C CE2   . TYR D 2 3   ? 156.323 127.911 168.562 1.00 130.34 ?  374 TYR E CE2   1 
ATOM 6052 C CZ    . TYR D 2 3   ? 156.885 127.573 167.347 1.00 130.34 ?  374 TYR E CZ    1 
ATOM 6053 O OH    . TYR D 2 3   ? 156.236 127.870 166.169 1.00 130.34 ?  374 TYR E OH    1 
ATOM 6054 N N     . TYR D 2 4   ? 156.513 124.607 170.677 1.00 126.93 ?  375 TYR E N     1 
ATOM 6055 C CA    . TYR D 2 4   ? 155.071 124.470 170.827 1.00 126.93 ?  375 TYR E CA    1 
ATOM 6056 C C     . TYR D 2 4   ? 154.717 123.241 171.655 1.00 126.93 ?  375 TYR E C     1 
ATOM 6057 O O     . TYR D 2 4   ? 153.603 123.142 172.181 1.00 126.93 ?  375 TYR E O     1 
ATOM 6058 C CB    . TYR D 2 4   ? 154.413 124.420 169.447 1.00 126.93 ?  375 TYR E CB    1 
ATOM 6059 C CG    . TYR D 2 4   ? 155.157 123.590 168.417 1.00 126.93 ?  375 TYR E CG    1 
ATOM 6060 C CD1   . TYR D 2 4   ? 155.454 122.257 168.656 1.00 126.93 ?  375 TYR E CD1   1 
ATOM 6061 C CD2   . TYR D 2 4   ? 155.591 124.149 167.220 1.00 126.93 ?  375 TYR E CD2   1 
ATOM 6062 C CE1   . TYR D 2 4   ? 156.133 121.495 167.727 1.00 126.93 ?  375 TYR E CE1   1 
ATOM 6063 C CE2   . TYR D 2 4   ? 156.282 123.395 166.289 1.00 126.93 ?  375 TYR E CE2   1 
ATOM 6064 C CZ    . TYR D 2 4   ? 156.549 122.071 166.547 1.00 126.93 ?  375 TYR E CZ    1 
ATOM 6065 O OH    . TYR D 2 4   ? 157.234 121.324 165.618 1.00 126.93 ?  375 TYR E OH    1 
ATOM 6066 N N     . LEU D 2 5   ? 155.654 122.296 171.781 1.00 126.43 ?  376 LEU E N     1 
ATOM 6067 C CA    . LEU D 2 5   ? 155.338 121.012 172.398 1.00 126.43 ?  376 LEU E CA    1 
ATOM 6068 C C     . LEU D 2 5   ? 155.384 121.080 173.920 1.00 126.43 ?  376 LEU E C     1 
ATOM 6069 O O     . LEU D 2 5   ? 154.465 120.592 174.588 1.00 126.43 ?  376 LEU E O     1 
ATOM 6070 C CB    . LEU D 2 5   ? 156.288 119.936 171.869 1.00 126.43 ?  376 LEU E CB    1 
ATOM 6071 C CG    . LEU D 2 5   ? 156.296 118.552 172.528 1.00 126.43 ?  376 LEU E CG    1 
ATOM 6072 C CD1   . LEU D 2 5   ? 156.678 117.502 171.514 1.00 126.43 ?  376 LEU E CD1   1 
ATOM 6073 C CD2   . LEU D 2 5   ? 157.279 118.485 173.688 1.00 126.43 ?  376 LEU E CD2   1 
ATOM 6074 N N     . ARG D 2 6   ? 156.445 121.661 174.491 1.00 127.24 ?  377 ARG E N     1 
ATOM 6075 C CA    . ARG D 2 6   ? 156.544 121.692 175.948 1.00 127.24 ?  377 ARG E CA    1 
ATOM 6076 C C     . ARG D 2 6   ? 155.383 122.466 176.553 1.00 127.24 ?  377 ARG E C     1 
ATOM 6077 O O     . ARG D 2 6   ? 154.784 122.026 177.540 1.00 127.24 ?  377 ARG E O     1 
ATOM 6078 C CB    . ARG D 2 6   ? 157.871 122.294 176.423 1.00 127.24 ?  377 ARG E CB    1 
ATOM 6079 C CG    . ARG D 2 6   ? 159.129 122.008 175.602 1.00 127.24 ?  377 ARG E CG    1 
ATOM 6080 C CD    . ARG D 2 6   ? 159.237 122.888 174.360 1.00 127.24 ?  377 ARG E CD    1 
ATOM 6081 N NE    . ARG D 2 6   ? 159.058 124.301 174.673 1.00 127.24 ?  377 ARG E NE    1 
ATOM 6082 C CZ    . ARG D 2 6   ? 160.043 125.132 174.988 1.00 127.24 ?  377 ARG E CZ    1 
ATOM 6083 N NH1   . ARG D 2 6   ? 161.300 124.723 175.054 1.00 127.24 1  377 ARG E NH1   1 
ATOM 6084 N NH2   . ARG D 2 6   ? 159.761 126.407 175.241 1.00 127.24 ?  377 ARG E NH2   1 
ATOM 6085 N N     . SER D 2 7   ? 155.038 123.613 175.963 1.00 123.38 ?  378 SER E N     1 
ATOM 6086 C CA    . SER D 2 7   ? 153.868 124.347 176.434 1.00 123.38 ?  378 SER E CA    1 
ATOM 6087 C C     . SER D 2 7   ? 152.605 123.518 176.261 1.00 123.38 ?  378 SER E C     1 
ATOM 6088 O O     . SER D 2 7   ? 151.665 123.624 177.058 1.00 123.38 ?  378 SER E O     1 
ATOM 6089 C CB    . SER D 2 7   ? 153.739 125.680 175.696 1.00 123.38 ?  378 SER E CB    1 
ATOM 6090 O OG    . SER D 2 7   ? 154.894 126.482 175.872 1.00 123.38 ?  378 SER E OG    1 
ATOM 6091 N N     . PHE D 2 8   ? 152.565 122.685 175.221 1.00 120.94 ?  379 PHE E N     1 
ATOM 6092 C CA    . PHE D 2 8   ? 151.435 121.786 175.035 1.00 120.94 ?  379 PHE E CA    1 
ATOM 6093 C C     . PHE D 2 8   ? 151.440 120.706 176.116 1.00 120.94 ?  379 PHE E C     1 
ATOM 6094 O O     . PHE D 2 8   ? 150.402 120.417 176.723 1.00 120.94 ?  379 PHE E O     1 
ATOM 6095 C CB    . PHE D 2 8   ? 151.509 121.196 173.622 1.00 120.94 ?  379 PHE E CB    1 
ATOM 6096 C CG    . PHE D 2 8   ? 150.284 120.438 173.177 1.00 120.94 ?  379 PHE E CG    1 
ATOM 6097 C CD1   . PHE D 2 8   ? 149.284 120.063 174.055 1.00 120.94 ?  379 PHE E CD1   1 
ATOM 6098 C CD2   . PHE D 2 8   ? 150.135 120.123 171.839 1.00 120.94 ?  379 PHE E CD2   1 
ATOM 6099 C CE1   . PHE D 2 8   ? 148.178 119.378 173.611 1.00 120.94 ?  379 PHE E CE1   1 
ATOM 6100 C CE2   . PHE D 2 8   ? 149.031 119.439 171.389 1.00 120.94 ?  379 PHE E CE2   1 
ATOM 6101 C CZ    . PHE D 2 8   ? 148.051 119.066 172.274 1.00 120.94 ?  379 PHE E CZ    1 
ATOM 6102 N N     . LEU D 2 9   ? 152.611 120.126 176.399 1.00 120.39 ?  380 LEU E N     1 
ATOM 6103 C CA    . LEU D 2 9   ? 152.697 119.114 177.449 1.00 120.39 ?  380 LEU E CA    1 
ATOM 6104 C C     . LEU D 2 9   ? 152.362 119.683 178.821 1.00 120.39 ?  380 LEU E C     1 
ATOM 6105 O O     . LEU D 2 9   ? 151.889 118.947 179.694 1.00 120.39 ?  380 LEU E O     1 
ATOM 6106 C CB    . LEU D 2 9   ? 154.087 118.479 177.477 1.00 120.39 ?  380 LEU E CB    1 
ATOM 6107 C CG    . LEU D 2 9   ? 154.395 117.446 176.395 1.00 120.39 ?  380 LEU E CG    1 
ATOM 6108 C CD1   . LEU D 2 9   ? 155.812 116.921 176.555 1.00 120.39 ?  380 LEU E CD1   1 
ATOM 6109 C CD2   . LEU D 2 9   ? 153.390 116.308 176.450 1.00 120.39 ?  380 LEU E CD2   1 
ATOM 6110 N N     . VAL D 2 10  ? 152.606 120.978 179.035 1.00 122.07 ?  381 VAL E N     1 
ATOM 6111 C CA    . VAL D 2 10  ? 152.251 121.597 180.309 1.00 122.07 ?  381 VAL E CA    1 
ATOM 6112 C C     . VAL D 2 10  ? 150.750 121.493 180.549 1.00 122.07 ?  381 VAL E C     1 
ATOM 6113 O O     . VAL D 2 10  ? 150.302 121.229 181.671 1.00 122.07 ?  381 VAL E O     1 
ATOM 6114 C CB    . VAL D 2 10  ? 152.734 123.059 180.349 1.00 122.07 ?  381 VAL E CB    1 
ATOM 6115 C CG1   . VAL D 2 10  ? 152.065 123.818 181.485 1.00 122.07 ?  381 VAL E CG1   1 
ATOM 6116 C CG2   . VAL D 2 10  ? 154.246 123.111 180.500 1.00 122.07 ?  381 VAL E CG2   1 
ATOM 6117 N N     . VAL D 2 11  ? 149.953 121.677 179.494 1.00 123.52 ?  382 VAL E N     1 
ATOM 6118 C CA    . VAL D 2 11  ? 148.500 121.647 179.639 1.00 123.52 ?  382 VAL E CA    1 
ATOM 6119 C C     . VAL D 2 11  ? 148.045 120.294 180.172 1.00 123.52 ?  382 VAL E C     1 
ATOM 6120 O O     . VAL D 2 11  ? 147.240 120.213 181.106 1.00 123.52 ?  382 VAL E O     1 
ATOM 6121 C CB    . VAL D 2 11  ? 147.822 121.979 178.297 1.00 123.52 ?  382 VAL E CB    1 
ATOM 6122 C CG1   . VAL D 2 11  ? 146.322 121.730 178.379 1.00 123.52 ?  382 VAL E CG1   1 
ATOM 6123 C CG2   . VAL D 2 11  ? 148.116 123.416 177.895 1.00 123.52 ?  382 VAL E CG2   1 
ATOM 6124 N N     . LEU D 2 12  ? 148.568 119.211 179.595 1.00 124.83 ?  383 LEU E N     1 
ATOM 6125 C CA    . LEU D 2 12  ? 148.165 117.879 180.035 1.00 124.83 ?  383 LEU E CA    1 
ATOM 6126 C C     . LEU D 2 12  ? 148.695 117.571 181.429 1.00 124.83 ?  383 LEU E C     1 
ATOM 6127 O O     . LEU D 2 12  ? 148.042 116.866 182.207 1.00 124.83 ?  383 LEU E O     1 
ATOM 6128 C CB    . LEU D 2 12  ? 148.644 116.825 179.036 1.00 124.83 ?  383 LEU E CB    1 
ATOM 6129 C CG    . LEU D 2 12  ? 147.847 116.666 177.738 1.00 124.83 ?  383 LEU E CG    1 
ATOM 6130 C CD1   . LEU D 2 12  ? 146.352 116.598 178.026 1.00 124.83 ?  383 LEU E CD1   1 
ATOM 6131 C CD2   . LEU D 2 12  ? 148.163 117.775 176.745 1.00 124.83 ?  383 LEU E CD2   1 
ATOM 6132 N N     . LYS D 2 13  ? 149.878 118.090 181.764 1.00 129.04 ?  384 LYS E N     1 
ATOM 6133 C CA    . LYS D 2 13  ? 150.512 117.731 183.028 1.00 129.04 ?  384 LYS E CA    1 
ATOM 6134 C C     . LYS D 2 13  ? 149.710 118.242 184.220 1.00 129.04 ?  384 LYS E C     1 
ATOM 6135 O O     . LYS D 2 13  ? 149.394 117.480 185.141 1.00 129.04 ?  384 LYS E O     1 
ATOM 6136 C CB    . LYS D 2 13  ? 151.942 118.271 183.065 1.00 129.04 ?  384 LYS E CB    1 
ATOM 6137 C CG    . LYS D 2 13  ? 152.676 117.982 184.362 1.00 129.04 ?  384 LYS E CG    1 
ATOM 6138 C CD    . LYS D 2 13  ? 154.067 118.589 184.354 1.00 129.04 ?  384 LYS E CD    1 
ATOM 6139 C CE    . LYS D 2 13  ? 155.085 117.613 183.789 1.00 129.04 ?  384 LYS E CE    1 
ATOM 6140 N NZ    . LYS D 2 13  ? 155.656 116.734 184.846 1.00 129.04 1  384 LYS E NZ    1 
ATOM 6141 N N     . THR D 2 14  ? 149.366 119.532 184.220 1.00 130.95 ?  385 THR E N     1 
ATOM 6142 C CA    . THR D 2 14  ? 148.634 120.096 185.351 1.00 130.95 ?  385 THR E CA    1 
ATOM 6143 C C     . THR D 2 14  ? 147.211 119.556 185.420 1.00 130.95 ?  385 THR E C     1 
ATOM 6144 O O     . THR D 2 14  ? 146.675 119.346 186.514 1.00 130.95 ?  385 THR E O     1 
ATOM 6145 C CB    . THR D 2 14  ? 148.620 121.623 185.273 1.00 130.95 ?  385 THR E CB    1 
ATOM 6146 O OG1   . THR D 2 14  ? 147.495 122.054 184.497 1.00 130.95 ?  385 THR E OG1   1 
ATOM 6147 C CG2   . THR D 2 14  ? 149.905 122.143 184.650 1.00 130.95 ?  385 THR E CG2   1 
ATOM 6148 N N     . VAL D 2 15  ? 146.578 119.338 184.265 1.00 130.62 ?  386 VAL E N     1 
ATOM 6149 C CA    . VAL D 2 15  ? 145.218 118.809 184.258 1.00 130.62 ?  386 VAL E CA    1 
ATOM 6150 C C     . VAL D 2 15  ? 145.189 117.401 184.839 1.00 130.62 ?  386 VAL E C     1 
ATOM 6151 O O     . VAL D 2 15  ? 144.307 117.060 185.637 1.00 130.62 ?  386 VAL E O     1 
ATOM 6152 C CB    . VAL D 2 15  ? 144.635 118.851 182.834 1.00 130.62 ?  386 VAL E CB    1 
ATOM 6153 C CG1   . VAL D 2 15  ? 143.350 118.046 182.766 1.00 130.62 ?  386 VAL E CG1   1 
ATOM 6154 C CG2   . VAL D 2 15  ? 144.384 120.290 182.423 1.00 130.62 ?  386 VAL E CG2   1 
ATOM 6155 N N     . LEU D 2 16  ? 146.155 116.566 184.462 1.00 130.86 ?  387 LEU E N     1 
ATOM 6156 C CA    . LEU D 2 16  ? 146.260 115.236 185.044 1.00 130.86 ?  387 LEU E CA    1 
ATOM 6157 C C     . LEU D 2 16  ? 146.687 115.266 186.505 1.00 130.86 ?  387 LEU E C     1 
ATOM 6158 O O     . LEU D 2 16  ? 146.609 114.233 187.178 1.00 130.86 ?  387 LEU E O     1 
ATOM 6159 C CB    . LEU D 2 16  ? 147.241 114.383 184.237 1.00 130.86 ?  387 LEU E CB    1 
ATOM 6160 C CG    . LEU D 2 16  ? 146.762 113.947 182.852 1.00 130.86 ?  387 LEU E CG    1 
ATOM 6161 C CD1   . LEU D 2 16  ? 147.852 113.178 182.124 1.00 130.86 ?  387 LEU E CD1   1 
ATOM 6162 C CD2   . LEU D 2 16  ? 145.492 113.117 182.958 1.00 130.86 ?  387 LEU E CD2   1 
ATOM 6163 N N     . GLU D 2 17  ? 147.133 116.419 187.008 1.00 136.22 ?  388 GLU E N     1 
ATOM 6164 C CA    . GLU D 2 17  ? 147.536 116.526 188.406 1.00 136.22 ?  388 GLU E CA    1 
ATOM 6165 C C     . GLU D 2 17  ? 146.331 116.742 189.315 1.00 136.22 ?  388 GLU E C     1 
ATOM 6166 O O     . GLU D 2 17  ? 146.135 116.000 190.284 1.00 136.22 ?  388 GLU E O     1 
ATOM 6167 C CB    . GLU D 2 17  ? 148.544 117.664 188.571 1.00 136.22 ?  388 GLU E CB    1 
ATOM 6168 C CG    . GLU D 2 17  ? 149.983 117.265 188.292 1.00 136.22 ?  388 GLU E CG    1 
ATOM 6169 C CD    . GLU D 2 17  ? 150.890 118.464 188.096 1.00 136.22 ?  388 GLU E CD    1 
ATOM 6170 O OE1   . GLU D 2 17  ? 150.387 119.606 188.148 1.00 136.22 ?  388 GLU E OE1   1 
ATOM 6171 O OE2   . GLU D 2 17  ? 152.105 118.265 187.886 1.00 136.22 -1 388 GLU E OE2   1 
ATOM 6172 N N     . ASN D 2 18  ? 145.519 117.755 189.021 1.00 140.47 ?  389 ASN E N     1 
ATOM 6173 C CA    . ASN D 2 18  ? 144.336 118.029 189.827 1.00 140.47 ?  389 ASN E CA    1 
ATOM 6174 C C     . ASN D 2 18  ? 143.330 116.894 189.681 1.00 140.47 ?  389 ASN E C     1 
ATOM 6175 O O     . ASN D 2 18  ? 143.059 116.432 188.570 1.00 140.47 ?  389 ASN E O     1 
ATOM 6176 C CB    . ASN D 2 18  ? 143.711 119.361 189.414 1.00 140.47 ?  389 ASN E CB    1 
ATOM 6177 C CG    . ASN D 2 18  ? 142.280 119.511 189.896 1.00 140.47 ?  389 ASN E CG    1 
ATOM 6178 O OD1   . ASN D 2 18  ? 141.340 119.063 189.241 1.00 140.47 ?  389 ASN E OD1   1 
ATOM 6179 N ND2   . ASN D 2 18  ? 142.109 120.146 191.050 1.00 140.47 ?  389 ASN E ND2   1 
ATOM 6180 N N     . GLU D 2 19  ? 142.773 116.451 190.810 1.00 140.42 ?  390 GLU E N     1 
ATOM 6181 C CA    . GLU D 2 19  ? 141.906 115.278 190.814 1.00 140.42 ?  390 GLU E CA    1 
ATOM 6182 C C     . GLU D 2 19  ? 140.499 115.576 190.309 1.00 140.42 ?  390 GLU E C     1 
ATOM 6183 O O     . GLU D 2 19  ? 139.777 114.641 189.946 1.00 140.42 ?  390 GLU E O     1 
ATOM 6184 C CB    . GLU D 2 19  ? 141.835 114.692 192.224 1.00 140.42 ?  390 GLU E CB    1 
ATOM 6185 C CG    . GLU D 2 19  ? 143.189 114.311 192.800 1.00 140.42 ?  390 GLU E CG    1 
ATOM 6186 C CD    . GLU D 2 19  ? 143.162 114.171 194.308 1.00 140.42 ?  390 GLU E CD    1 
ATOM 6187 O OE1   . GLU D 2 19  ? 142.086 114.380 194.907 1.00 140.42 ?  390 GLU E OE1   1 
ATOM 6188 O OE2   . GLU D 2 19  ? 144.218 113.853 194.896 1.00 140.42 -1 390 GLU E OE2   1 
ATOM 6189 N N     . ASP D 2 20  ? 140.091 116.844 190.281 1.00 137.02 ?  391 ASP E N     1 
ATOM 6190 C CA    . ASP D 2 20  ? 138.738 117.186 189.858 1.00 137.02 ?  391 ASP E CA    1 
ATOM 6191 C C     . ASP D 2 20  ? 138.572 117.182 188.344 1.00 137.02 ?  391 ASP E C     1 
ATOM 6192 O O     . ASP D 2 20  ? 137.435 117.161 187.860 1.00 137.02 ?  391 ASP E O     1 
ATOM 6193 C CB    . ASP D 2 20  ? 138.349 118.560 190.413 1.00 137.02 ?  391 ASP E CB    1 
ATOM 6194 C CG    . ASP D 2 20  ? 136.877 118.653 190.767 1.00 137.02 ?  391 ASP E CG    1 
ATOM 6195 O OD1   . ASP D 2 20  ? 136.078 117.865 190.220 1.00 137.02 ?  391 ASP E OD1   1 
ATOM 6196 O OD2   . ASP D 2 20  ? 136.518 119.516 191.595 1.00 137.02 -1 391 ASP E OD2   1 
ATOM 6197 N N     . ASP D 2 21  ? 139.671 117.198 187.588 1.00 140.33 ?  392 ASP E N     1 
ATOM 6198 C CA    . ASP D 2 21  ? 139.570 117.324 186.138 1.00 140.33 ?  392 ASP E CA    1 
ATOM 6199 C C     . ASP D 2 21  ? 139.056 116.039 185.495 1.00 140.33 ?  392 ASP E C     1 
ATOM 6200 O O     . ASP D 2 21  ? 138.182 116.080 184.622 1.00 140.33 ?  392 ASP E O     1 
ATOM 6201 C CB    . ASP D 2 21  ? 140.925 117.724 185.556 1.00 140.33 ?  392 ASP E CB    1 
ATOM 6202 C CG    . ASP D 2 21  ? 141.439 119.029 186.133 1.00 140.33 ?  392 ASP E CG    1 
ATOM 6203 O OD1   . ASP D 2 21  ? 140.606 119.868 186.537 1.00 140.33 ?  392 ASP E OD1   1 
ATOM 6204 O OD2   . ASP D 2 21  ? 142.671 119.219 186.189 1.00 140.33 -1 392 ASP E OD2   1 
ATOM 6205 N N     . MET D 2 22  ? 139.583 114.886 185.913 1.00 138.36 ?  393 MET E N     1 
ATOM 6206 C CA    . MET D 2 22  ? 139.151 113.627 185.318 1.00 138.36 ?  393 MET E CA    1 
ATOM 6207 C C     . MET D 2 22  ? 137.765 113.196 185.779 1.00 138.36 ?  393 MET E C     1 
ATOM 6208 O O     . MET D 2 22  ? 137.214 112.248 185.210 1.00 138.36 ?  393 MET E O     1 
ATOM 6209 C CB    . MET D 2 22  ? 140.154 112.510 185.619 1.00 138.36 ?  393 MET E CB    1 
ATOM 6210 C CG    . MET D 2 22  ? 140.704 112.512 187.031 1.00 138.36 ?  393 MET E CG    1 
ATOM 6211 S SD    . MET D 2 22  ? 141.596 114.026 187.409 1.00 138.36 ?  393 MET E SD    1 
ATOM 6212 C CE    . MET D 2 22  ? 142.881 113.984 186.163 1.00 138.36 ?  393 MET E CE    1 
ATOM 6213 N N     . LEU D 2 23  ? 137.194 113.857 186.788 1.00 135.18 ?  394 LEU E N     1 
ATOM 6214 C CA    . LEU D 2 23  ? 135.869 113.477 187.263 1.00 135.18 ?  394 LEU E CA    1 
ATOM 6215 C C     . LEU D 2 23  ? 134.785 113.744 186.227 1.00 135.18 ?  394 LEU E C     1 
ATOM 6216 O O     . LEU D 2 23  ? 133.728 113.105 186.273 1.00 135.18 ?  394 LEU E O     1 
ATOM 6217 C CB    . LEU D 2 23  ? 135.546 114.212 188.564 1.00 135.18 ?  394 LEU E CB    1 
ATOM 6218 C CG    . LEU D 2 23  ? 136.418 113.830 189.762 1.00 135.18 ?  394 LEU E CG    1 
ATOM 6219 C CD1   . LEU D 2 23  ? 136.115 114.714 190.961 1.00 135.18 ?  394 LEU E CD1   1 
ATOM 6220 C CD2   . LEU D 2 23  ? 136.229 112.362 190.112 1.00 135.18 ?  394 LEU E CD2   1 
ATOM 6221 N N     . LEU D 2 24  ? 135.020 114.668 185.297 1.00 132.74 ?  395 LEU E N     1 
ATOM 6222 C CA    . LEU D 2 24  ? 134.086 114.945 184.215 1.00 132.74 ?  395 LEU E CA    1 
ATOM 6223 C C     . LEU D 2 24  ? 134.394 114.139 182.960 1.00 132.74 ?  395 LEU E C     1 
ATOM 6224 O O     . LEU D 2 24  ? 133.686 114.278 181.957 1.00 132.74 ?  395 LEU E O     1 
ATOM 6225 C CB    . LEU D 2 24  ? 134.082 116.440 183.889 1.00 132.74 ?  395 LEU E CB    1 
ATOM 6226 C CG    . LEU D 2 24  ? 134.054 117.394 185.084 1.00 132.74 ?  395 LEU E CG    1 
ATOM 6227 C CD1   . LEU D 2 24  ? 134.169 118.837 184.618 1.00 132.74 ?  395 LEU E CD1   1 
ATOM 6228 C CD2   . LEU D 2 24  ? 132.789 117.190 185.905 1.00 132.74 ?  395 LEU E CD2   1 
ATOM 6229 N N     . PHE D 2 25  ? 135.428 113.303 182.993 1.00 136.07 ?  396 PHE E N     1 
ATOM 6230 C CA    . PHE D 2 25  ? 135.821 112.486 181.854 1.00 136.07 ?  396 PHE E CA    1 
ATOM 6231 C C     . PHE D 2 25  ? 135.664 111.014 182.204 1.00 136.07 ?  396 PHE E C     1 
ATOM 6232 O O     . PHE D 2 25  ? 136.029 110.585 183.302 1.00 136.07 ?  396 PHE E O     1 
ATOM 6233 C CB    . PHE D 2 25  ? 137.267 112.771 181.430 1.00 136.07 ?  396 PHE E CB    1 
ATOM 6234 C CG    . PHE D 2 25  ? 137.452 114.101 180.754 1.00 136.07 ?  396 PHE E CG    1 
ATOM 6235 C CD1   . PHE D 2 25  ? 136.360 114.837 180.326 1.00 136.07 ?  396 PHE E CD1   1 
ATOM 6236 C CD2   . PHE D 2 25  ? 138.722 114.614 180.547 1.00 136.07 ?  396 PHE E CD2   1 
ATOM 6237 C CE1   . PHE D 2 25  ? 136.531 116.060 179.705 1.00 136.07 ?  396 PHE E CE1   1 
ATOM 6238 C CE2   . PHE D 2 25  ? 138.899 115.836 179.927 1.00 136.07 ?  396 PHE E CE2   1 
ATOM 6239 C CZ    . PHE D 2 25  ? 137.802 116.560 179.505 1.00 136.07 ?  396 PHE E CZ    1 
ATOM 6240 N N     . ASP D 2 26  ? 135.123 110.243 181.263 1.00 138.50 ?  397 ASP E N     1 
ATOM 6241 C CA    . ASP D 2 26  ? 134.887 108.824 181.473 1.00 138.50 ?  397 ASP E CA    1 
ATOM 6242 C C     . ASP D 2 26  ? 136.165 108.021 181.222 1.00 138.50 ?  397 ASP E C     1 
ATOM 6243 O O     . ASP D 2 26  ? 137.243 108.570 180.985 1.00 138.50 ?  397 ASP E O     1 
ATOM 6244 C CB    . ASP D 2 26  ? 133.711 108.353 180.611 1.00 138.50 ?  397 ASP E CB    1 
ATOM 6245 C CG    . ASP D 2 26  ? 134.101 108.037 179.169 1.00 138.50 ?  397 ASP E CG    1 
ATOM 6246 O OD1   . ASP D 2 26  ? 133.269 107.428 178.464 1.00 138.50 ?  397 ASP E OD1   1 
ATOM 6247 O OD2   . ASP D 2 26  ? 135.194 108.428 178.713 1.00 138.50 -1 397 ASP E OD2   1 
ATOM 6248 N N     . GLU D 2 27  ? 136.035 106.693 181.275 1.00 138.05 ?  398 GLU E N     1 
ATOM 6249 C CA    . GLU D 2 27  ? 137.205 105.823 181.176 1.00 138.05 ?  398 GLU E CA    1 
ATOM 6250 C C     . GLU D 2 27  ? 137.874 105.919 179.808 1.00 138.05 ?  398 GLU E C     1 
ATOM 6251 O O     . GLU D 2 27  ? 139.107 105.955 179.720 1.00 138.05 ?  398 GLU E O     1 
ATOM 6252 C CB    . GLU D 2 27  ? 136.813 104.378 181.505 1.00 138.05 ?  398 GLU E CB    1 
ATOM 6253 C CG    . GLU D 2 27  ? 135.984 103.653 180.447 1.00 138.05 ?  398 GLU E CG    1 
ATOM 6254 C CD    . GLU D 2 27  ? 134.571 104.193 180.326 1.00 138.05 ?  398 GLU E CD    1 
ATOM 6255 O OE1   . GLU D 2 27  ? 134.112 104.886 181.258 1.00 138.05 ?  398 GLU E OE1   1 
ATOM 6256 O OE2   . GLU D 2 27  ? 133.918 103.925 179.295 1.00 138.05 -1 398 GLU E OE2   1 
ATOM 6257 N N     . GLN D 2 28  ? 137.089 105.968 178.728 1.00 132.21 ?  399 GLN E N     1 
ATOM 6258 C CA    . GLN D 2 28  ? 137.694 106.020 177.400 1.00 132.21 ?  399 GLN E CA    1 
ATOM 6259 C C     . GLN D 2 28  ? 138.270 107.400 177.115 1.00 132.21 ?  399 GLN E C     1 
ATOM 6260 O O     . GLN D 2 28  ? 139.207 107.537 176.320 1.00 132.21 ?  399 GLN E O     1 
ATOM 6261 C CB    . GLN D 2 28  ? 136.679 105.546 176.341 1.00 132.21 ?  399 GLN E CB    1 
ATOM 6262 C CG    . GLN D 2 28  ? 135.328 106.294 176.117 1.00 132.21 ?  399 GLN E CG    1 
ATOM 6263 C CD    . GLN D 2 28  ? 135.383 107.795 175.841 1.00 132.21 ?  399 GLN E CD    1 
ATOM 6264 O OE1   . GLN D 2 28  ? 136.408 108.346 175.451 1.00 132.21 ?  399 GLN E OE1   1 
ATOM 6265 N NE2   . GLN D 2 28  ? 134.254 108.462 176.046 1.00 132.21 ?  399 GLN E NE2   1 
ATOM 6266 N N     . GLU D 2 29  ? 137.723 108.435 177.757 1.00 130.49 ?  400 GLU E N     1 
ATOM 6267 C CA    . GLU D 2 29  ? 138.298 109.769 177.631 1.00 130.49 ?  400 GLU E CA    1 
ATOM 6268 C C     . GLU D 2 29  ? 139.663 109.854 178.302 1.00 130.49 ?  400 GLU E C     1 
ATOM 6269 O O     . GLU D 2 29  ? 140.512 110.646 177.879 1.00 130.49 ?  400 GLU E O     1 
ATOM 6270 C CB    . GLU D 2 29  ? 137.339 110.810 178.210 1.00 130.49 ?  400 GLU E CB    1 
ATOM 6271 C CG    . GLU D 2 29  ? 136.171 111.134 177.285 1.00 130.49 ?  400 GLU E CG    1 
ATOM 6272 C CD    . GLU D 2 29  ? 134.906 111.519 178.025 1.00 130.49 ?  400 GLU E CD    1 
ATOM 6273 O OE1   . GLU D 2 29  ? 134.767 111.148 179.206 1.00 130.49 ?  400 GLU E OE1   1 
ATOM 6274 O OE2   . GLU D 2 29  ? 134.046 112.194 177.421 1.00 130.49 -1 400 GLU E OE2   1 
ATOM 6275 N N     . LYS D 2 30  ? 139.890 109.059 179.349 1.00 122.59 ?  401 LYS E N     1 
ATOM 6276 C CA    . LYS D 2 30  ? 141.225 108.961 179.928 1.00 122.59 ?  401 LYS E CA    1 
ATOM 6277 C C     . LYS D 2 30  ? 142.114 108.007 179.144 1.00 122.59 ?  401 LYS E C     1 
ATOM 6278 O O     . LYS D 2 30  ? 143.343 108.087 179.244 1.00 122.59 ?  401 LYS E O     1 
ATOM 6279 C CB    . LYS D 2 30  ? 141.141 108.517 181.390 1.00 122.59 ?  401 LYS E CB    1 
ATOM 6280 C CG    . LYS D 2 30  ? 140.149 109.300 182.244 1.00 122.59 ?  401 LYS E CG    1 
ATOM 6281 C CD    . LYS D 2 30  ? 140.293 110.806 182.059 1.00 122.59 ?  401 LYS E CD    1 
ATOM 6282 C CE    . LYS D 2 30  ? 141.654 111.301 182.533 1.00 122.59 ?  401 LYS E CE    1 
ATOM 6283 N NZ    . LYS D 2 30  ? 141.712 112.787 182.610 1.00 122.59 1  401 LYS E NZ    1 
ATOM 6284 N N     . GLY D 2 31  ? 141.519 107.092 178.376 1.00 112.67 ?  402 GLY E N     1 
ATOM 6285 C CA    . GLY D 2 31  ? 142.316 106.170 177.588 1.00 112.67 ?  402 GLY E CA    1 
ATOM 6286 C C     . GLY D 2 31  ? 142.859 106.766 176.309 1.00 112.67 ?  402 GLY E C     1 
ATOM 6287 O O     . GLY D 2 31  ? 143.932 106.367 175.848 1.00 112.67 ?  402 GLY E O     1 
ATOM 6288 N N     . ILE D 2 32  ? 142.142 107.725 175.719 1.00 110.74 ?  403 ILE E N     1 
ATOM 6289 C CA    . ILE D 2 32  ? 142.590 108.304 174.457 1.00 110.74 ?  403 ILE E CA    1 
ATOM 6290 C C     . ILE D 2 32  ? 143.828 109.165 174.672 1.00 110.74 ?  403 ILE E C     1 
ATOM 6291 O O     . ILE D 2 32  ? 144.779 109.116 173.882 1.00 110.74 ?  403 ILE E O     1 
ATOM 6292 C CB    . ILE D 2 32  ? 141.446 109.092 173.790 1.00 110.74 ?  403 ILE E CB    1 
ATOM 6293 C CG1   . ILE D 2 32  ? 141.972 109.902 172.606 1.00 110.74 ?  403 ILE E CG1   1 
ATOM 6294 C CG2   . ILE D 2 32  ? 140.749 109.992 174.794 1.00 110.74 ?  403 ILE E CG2   1 
ATOM 6295 C CD1   . ILE D 2 32  ? 140.962 110.067 171.498 1.00 110.74 ?  403 ILE E CD1   1 
ATOM 6296 N N     . VAL D 2 33  ? 143.844 109.961 175.743 1.00 112.10 ?  404 VAL E N     1 
ATOM 6297 C CA    . VAL D 2 33  ? 145.039 110.730 176.071 1.00 112.10 ?  404 VAL E CA    1 
ATOM 6298 C C     . VAL D 2 33  ? 146.189 109.794 176.420 1.00 112.10 ?  404 VAL E C     1 
ATOM 6299 O O     . VAL D 2 33  ? 147.357 110.106 176.159 1.00 112.10 ?  404 VAL E O     1 
ATOM 6300 C CB    . VAL D 2 33  ? 144.733 111.727 177.206 1.00 112.10 ?  404 VAL E CB    1 
ATOM 6301 C CG1   . VAL D 2 33  ? 144.036 111.030 178.361 1.00 112.10 ?  404 VAL E CG1   1 
ATOM 6302 C CG2   . VAL D 2 33  ? 146.001 112.426 177.677 1.00 112.10 ?  404 VAL E CG2   1 
ATOM 6303 N N     . THR D 2 34  ? 145.883 108.629 176.997 1.00 112.94 ?  405 THR E N     1 
ATOM 6304 C CA    . THR D 2 34  ? 146.921 107.635 177.244 1.00 112.94 ?  405 THR E CA    1 
ATOM 6305 C C     . THR D 2 34  ? 147.557 107.169 175.941 1.00 112.94 ?  405 THR E C     1 
ATOM 6306 O O     . THR D 2 34  ? 148.781 107.008 175.862 1.00 112.94 ?  405 THR E O     1 
ATOM 6307 C CB    . THR D 2 34  ? 146.341 106.448 178.012 1.00 112.94 ?  405 THR E CB    1 
ATOM 6308 O OG1   . THR D 2 34  ? 145.336 106.912 178.922 1.00 112.94 ?  405 THR E OG1   1 
ATOM 6309 C CG2   . THR D 2 34  ? 147.434 105.737 178.793 1.00 112.94 ?  405 THR E CG2   1 
ATOM 6310 N N     . LYS D 2 35  ? 146.743 106.947 174.904 1.00 112.93 ?  406 LYS E N     1 
ATOM 6311 C CA    . LYS D 2 35  ? 147.296 106.567 173.608 1.00 112.93 ?  406 LYS E CA    1 
ATOM 6312 C C     . LYS D 2 35  ? 148.177 107.664 173.032 1.00 112.93 ?  406 LYS E C     1 
ATOM 6313 O O     . LYS D 2 35  ? 149.136 107.372 172.309 1.00 112.93 ?  406 LYS E O     1 
ATOM 6314 C CB    . LYS D 2 35  ? 146.177 106.209 172.629 1.00 112.93 ?  406 LYS E CB    1 
ATOM 6315 C CG    . LYS D 2 35  ? 145.192 105.182 173.160 1.00 112.93 ?  406 LYS E CG    1 
ATOM 6316 C CD    . LYS D 2 35  ? 143.785 105.442 172.653 1.00 112.93 ?  406 LYS E CD    1 
ATOM 6317 C CE    . LYS D 2 35  ? 142.773 104.571 173.378 1.00 112.93 ?  406 LYS E CE    1 
ATOM 6318 N NZ    . LYS D 2 35  ? 141.494 105.291 173.625 1.00 112.93 1  406 LYS E NZ    1 
ATOM 6319 N N     . PHE D 2 36  ? 147.872 108.927 173.338 1.00 115.24 ?  407 PHE E N     1 
ATOM 6320 C CA    . PHE D 2 36  ? 148.742 110.022 172.923 1.00 115.24 ?  407 PHE E CA    1 
ATOM 6321 C C     . PHE D 2 36  ? 150.133 109.843 173.523 1.00 115.24 ?  407 PHE E C     1 
ATOM 6322 O O     . PHE D 2 36  ? 151.143 109.951 172.818 1.00 115.24 ?  407 PHE E O     1 
ATOM 6323 C CB    . PHE D 2 36  ? 148.104 111.353 173.350 1.00 115.24 ?  407 PHE E CB    1 
ATOM 6324 C CG    . PHE D 2 36  ? 148.782 112.605 172.816 1.00 115.24 ?  407 PHE E CG    1 
ATOM 6325 C CD1   . PHE D 2 36  ? 148.087 113.803 172.814 1.00 115.24 ?  407 PHE E CD1   1 
ATOM 6326 C CD2   . PHE D 2 36  ? 150.069 112.599 172.304 1.00 115.24 ?  407 PHE E CD2   1 
ATOM 6327 C CE1   . PHE D 2 36  ? 148.665 114.963 172.336 1.00 115.24 ?  407 PHE E CE1   1 
ATOM 6328 C CE2   . PHE D 2 36  ? 150.651 113.756 171.826 1.00 115.24 ?  407 PHE E CE2   1 
ATOM 6329 C CZ    . PHE D 2 36  ? 149.948 114.937 171.840 1.00 115.24 ?  407 PHE E CZ    1 
ATOM 6330 N N     . TYR D 2 37  ? 150.201 109.521 174.818 1.00 118.96 ?  408 TYR E N     1 
ATOM 6331 C CA    . TYR D 2 37  ? 151.494 109.383 175.480 1.00 118.96 ?  408 TYR E CA    1 
ATOM 6332 C C     . TYR D 2 37  ? 152.329 108.255 174.886 1.00 118.96 ?  408 TYR E C     1 
ATOM 6333 O O     . TYR D 2 37  ? 153.537 108.424 174.684 1.00 118.96 ?  408 TYR E O     1 
ATOM 6334 C CB    . TYR D 2 37  ? 151.296 109.164 176.980 1.00 118.96 ?  408 TYR E CB    1 
ATOM 6335 C CG    . TYR D 2 37  ? 150.970 110.428 177.741 1.00 118.96 ?  408 TYR E CG    1 
ATOM 6336 C CD1   . TYR D 2 37  ? 151.859 111.495 177.757 1.00 118.96 ?  408 TYR E CD1   1 
ATOM 6337 C CD2   . TYR D 2 37  ? 149.781 110.556 178.447 1.00 118.96 ?  408 TYR E CD2   1 
ATOM 6338 C CE1   . TYR D 2 37  ? 151.573 112.654 178.450 1.00 118.96 ?  408 TYR E CE1   1 
ATOM 6339 C CE2   . TYR D 2 37  ? 149.486 111.713 179.145 1.00 118.96 ?  408 TYR E CE2   1 
ATOM 6340 C CZ    . TYR D 2 37  ? 150.387 112.759 179.143 1.00 118.96 ?  408 TYR E CZ    1 
ATOM 6341 O OH    . TYR D 2 37  ? 150.102 113.914 179.834 1.00 118.96 ?  408 TYR E OH    1 
ATOM 6342 N N     . GLN D 2 38  ? 151.716 107.108 174.588 1.00 121.17 ?  409 GLN E N     1 
ATOM 6343 C CA    . GLN D 2 38  ? 152.489 106.002 174.035 1.00 121.17 ?  409 GLN E CA    1 
ATOM 6344 C C     . GLN D 2 38  ? 152.896 106.224 172.584 1.00 121.17 ?  409 GLN E C     1 
ATOM 6345 O O     . GLN D 2 38  ? 153.677 105.426 172.054 1.00 121.17 ?  409 GLN E O     1 
ATOM 6346 C CB    . GLN D 2 38  ? 151.725 104.682 174.174 1.00 121.17 ?  409 GLN E CB    1 
ATOM 6347 C CG    . GLN D 2 38  ? 150.413 104.609 173.421 1.00 121.17 ?  409 GLN E CG    1 
ATOM 6348 C CD    . GLN D 2 38  ? 149.383 103.771 174.155 1.00 121.17 ?  409 GLN E CD    1 
ATOM 6349 O OE1   . GLN D 2 38  ? 148.744 104.234 175.100 1.00 121.17 ?  409 GLN E OE1   1 
ATOM 6350 N NE2   . GLN D 2 38  ? 149.216 102.528 173.720 1.00 121.17 ?  409 GLN E NE2   1 
ATOM 6351 N N     . LEU D 2 39  ? 152.398 107.271 171.930 1.00 121.03 ?  410 LEU E N     1 
ATOM 6352 C CA    . LEU D 2 39  ? 152.911 107.618 170.615 1.00 121.03 ?  410 LEU E CA    1 
ATOM 6353 C C     . LEU D 2 39  ? 154.370 108.054 170.718 1.00 121.03 ?  410 LEU E C     1 
ATOM 6354 O O     . LEU D 2 39  ? 154.821 108.578 171.741 1.00 121.03 ?  410 LEU E O     1 
ATOM 6355 C CB    . LEU D 2 39  ? 152.088 108.738 169.980 1.00 121.03 ?  410 LEU E CB    1 
ATOM 6356 C CG    . LEU D 2 39  ? 150.580 108.560 169.817 1.00 121.03 ?  410 LEU E CG    1 
ATOM 6357 C CD1   . LEU D 2 39  ? 149.952 109.857 169.336 1.00 121.03 ?  410 LEU E CD1   1 
ATOM 6358 C CD2   . LEU D 2 39  ? 150.265 107.420 168.862 1.00 121.03 ?  410 LEU E CD2   1 
ATOM 6359 N N     . SER D 2 40  ? 155.110 107.832 169.637 1.00 121.00 ?  411 SER E N     1 
ATOM 6360 C CA    . SER D 2 40  ? 156.503 108.241 169.597 1.00 121.00 ?  411 SER E CA    1 
ATOM 6361 C C     . SER D 2 40  ? 156.605 109.763 169.527 1.00 121.00 ?  411 SER E C     1 
ATOM 6362 O O     . SER D 2 40  ? 155.624 110.472 169.284 1.00 121.00 ?  411 SER E O     1 
ATOM 6363 C CB    . SER D 2 40  ? 157.215 107.604 168.404 1.00 121.00 ?  411 SER E CB    1 
ATOM 6364 O OG    . SER D 2 40  ? 156.808 108.204 167.187 1.00 121.00 ?  411 SER E OG    1 
ATOM 6365 N N     . ALA D 2 41  ? 157.821 110.266 169.754 1.00 120.55 ?  412 ALA E N     1 
ATOM 6366 C CA    . ALA D 2 41  ? 158.052 111.704 169.664 1.00 120.55 ?  412 ALA E CA    1 
ATOM 6367 C C     . ALA D 2 41  ? 157.708 112.226 168.276 1.00 120.55 ?  412 ALA E C     1 
ATOM 6368 O O     . ALA D 2 41  ? 157.146 113.319 168.136 1.00 120.55 ?  412 ALA E O     1 
ATOM 6369 C CB    . ALA D 2 41  ? 159.503 112.028 170.017 1.00 120.55 ?  412 ALA E CB    1 
ATOM 6370 N N     . THR D 2 42  ? 158.043 111.460 167.237 1.00 122.74 ?  413 THR E N     1 
ATOM 6371 C CA    . THR D 2 42  ? 157.649 111.837 165.884 1.00 122.74 ?  413 THR E CA    1 
ATOM 6372 C C     . THR D 2 42  ? 156.133 111.842 165.732 1.00 122.74 ?  413 THR E C     1 
ATOM 6373 O O     . THR D 2 42  ? 155.565 112.758 165.127 1.00 122.74 ?  413 THR E O     1 
ATOM 6374 C CB    . THR D 2 42  ? 158.284 110.887 164.869 1.00 122.74 ?  413 THR E CB    1 
ATOM 6375 O OG1   . THR D 2 42  ? 159.583 110.492 165.330 1.00 122.74 ?  413 THR E OG1   1 
ATOM 6376 C CG2   . THR D 2 42  ? 158.413 111.563 163.513 1.00 122.74 ?  413 THR E CG2   1 
ATOM 6377 N N     . GLY D 2 43  ? 155.462 110.824 166.273 1.00 122.17 ?  414 GLY E N     1 
ATOM 6378 C CA    . GLY D 2 43  ? 154.013 110.769 166.172 1.00 122.17 ?  414 GLY E CA    1 
ATOM 6379 C C     . GLY D 2 43  ? 153.324 111.855 166.975 1.00 122.17 ?  414 GLY E C     1 
ATOM 6380 O O     . GLY D 2 43  ? 152.343 112.449 166.521 1.00 122.17 ?  414 GLY E O     1 
ATOM 6381 N N     . GLN D 2 44  ? 153.824 112.126 168.183 1.00 120.49 ?  415 GLN E N     1 
ATOM 6382 C CA    . GLN D 2 44  ? 153.184 113.115 169.045 1.00 120.49 ?  415 GLN E CA    1 
ATOM 6383 C C     . GLN D 2 44  ? 153.258 114.518 168.457 1.00 120.49 ?  415 GLN E C     1 
ATOM 6384 O O     . GLN D 2 44  ? 152.290 115.279 168.557 1.00 120.49 ?  415 GLN E O     1 
ATOM 6385 C CB    . GLN D 2 44  ? 153.817 113.086 170.436 1.00 120.49 ?  415 GLN E CB    1 
ATOM 6386 C CG    . GLN D 2 44  ? 153.496 111.831 171.234 1.00 120.49 ?  415 GLN E CG    1 
ATOM 6387 C CD    . GLN D 2 44  ? 154.056 111.872 172.641 1.00 120.49 ?  415 GLN E CD    1 
ATOM 6388 O OE1   . GLN D 2 44  ? 154.579 112.894 173.084 1.00 120.49 ?  415 GLN E OE1   1 
ATOM 6389 N NE2   . GLN D 2 44  ? 153.947 110.757 173.354 1.00 120.49 ?  415 GLN E NE2   1 
ATOM 6390 N N     . LYS D 2 45  ? 154.388 114.879 167.844 1.00 119.73 ?  416 LYS E N     1 
ATOM 6391 C CA    . LYS D 2 45  ? 154.541 116.233 167.319 1.00 119.73 ?  416 LYS E CA    1 
ATOM 6392 C C     . LYS D 2 45  ? 153.628 116.478 166.125 1.00 119.73 ?  416 LYS E C     1 
ATOM 6393 O O     . LYS D 2 45  ? 153.171 117.606 165.908 1.00 119.73 ?  416 LYS E O     1 
ATOM 6394 C CB    . LYS D 2 45  ? 156.000 116.492 166.944 1.00 119.73 ?  416 LYS E CB    1 
ATOM 6395 C CG    . LYS D 2 45  ? 156.939 116.518 168.135 1.00 119.73 ?  416 LYS E CG    1 
ATOM 6396 C CD    . LYS D 2 45  ? 158.394 116.625 167.715 1.00 119.73 ?  416 LYS E CD    1 
ATOM 6397 C CE    . LYS D 2 45  ? 159.321 116.210 168.846 1.00 119.73 ?  416 LYS E CE    1 
ATOM 6398 N NZ    . LYS D 2 45  ? 160.755 116.334 168.466 1.00 119.73 1  416 LYS E NZ    1 
ATOM 6399 N N     . LEU D 2 46  ? 153.358 115.440 165.331 1.00 111.65 ?  417 LEU E N     1 
ATOM 6400 C CA    . LEU D 2 46  ? 152.517 115.618 164.152 1.00 111.65 ?  417 LEU E CA    1 
ATOM 6401 C C     . LEU D 2 46  ? 151.099 116.018 164.540 1.00 111.65 ?  417 LEU E C     1 
ATOM 6402 O O     . LEU D 2 46  ? 150.492 116.885 163.900 1.00 111.65 ?  417 LEU E O     1 
ATOM 6403 C CB    . LEU D 2 46  ? 152.504 114.339 163.317 1.00 111.65 ?  417 LEU E CB    1 
ATOM 6404 C CG    . LEU D 2 46  ? 151.757 114.411 161.984 1.00 111.65 ?  417 LEU E CG    1 
ATOM 6405 C CD1   . LEU D 2 46  ? 152.063 115.718 161.264 1.00 111.65 ?  417 LEU E CD1   1 
ATOM 6406 C CD2   . LEU D 2 46  ? 152.106 113.220 161.107 1.00 111.65 ?  417 LEU E CD2   1 
ATOM 6407 N N     . TYR D 2 47  ? 150.554 115.398 165.588 1.00 106.80 ?  418 TYR E N     1 
ATOM 6408 C CA    . TYR D 2 47  ? 149.202 115.731 166.024 1.00 106.80 ?  418 TYR E CA    1 
ATOM 6409 C C     . TYR D 2 47  ? 149.137 117.143 166.594 1.00 106.80 ?  418 TYR E C     1 
ATOM 6410 O O     . TYR D 2 47  ? 148.058 117.742 166.661 1.00 106.80 ?  418 TYR E O     1 
ATOM 6411 C CB    . TYR D 2 47  ? 148.724 114.708 167.055 1.00 106.80 ?  418 TYR E CB    1 
ATOM 6412 C CG    . TYR D 2 47  ? 147.280 114.867 167.472 1.00 106.80 ?  418 TYR E CG    1 
ATOM 6413 C CD1   . TYR D 2 47  ? 146.921 114.868 168.812 1.00 106.80 ?  418 TYR E CD1   1 
ATOM 6414 C CD2   . TYR D 2 47  ? 146.274 115.003 166.526 1.00 106.80 ?  418 TYR E CD2   1 
ATOM 6415 C CE1   . TYR D 2 47  ? 145.602 115.007 169.199 1.00 106.80 ?  418 TYR E CE1   1 
ATOM 6416 C CE2   . TYR D 2 47  ? 144.953 115.142 166.904 1.00 106.80 ?  418 TYR E CE2   1 
ATOM 6417 C CZ    . TYR D 2 47  ? 144.622 115.144 168.241 1.00 106.80 ?  418 TYR E CZ    1 
ATOM 6418 O OH    . TYR D 2 47  ? 143.307 115.283 168.620 1.00 106.80 ?  418 TYR E OH    1 
ATOM 6419 N N     . VAL D 2 48  ? 150.280 117.687 167.015 1.00 111.90 ?  419 VAL E N     1 
ATOM 6420 C CA    . VAL D 2 48  ? 150.303 119.028 167.592 1.00 111.90 ?  419 VAL E CA    1 
ATOM 6421 C C     . VAL D 2 48  ? 149.956 120.073 166.539 1.00 111.90 ?  419 VAL E C     1 
ATOM 6422 O O     . VAL D 2 48  ? 149.125 120.959 166.772 1.00 111.90 ?  419 VAL E O     1 
ATOM 6423 C CB    . VAL D 2 48  ? 151.676 119.309 168.229 1.00 111.90 ?  419 VAL E CB    1 
ATOM 6424 C CG1   . VAL D 2 48  ? 151.800 120.778 168.611 1.00 111.90 ?  419 VAL E CG1   1 
ATOM 6425 C CG2   . VAL D 2 48  ? 151.905 118.404 169.429 1.00 111.90 ?  419 VAL E CG2   1 
ATOM 6426 N N     . ARG D 2 49  ? 150.582 119.983 165.364 1.00 116.05 ?  420 ARG E N     1 
ATOM 6427 C CA    . ARG D 2 49  ? 150.403 121.012 164.345 1.00 116.05 ?  420 ARG E CA    1 
ATOM 6428 C C     . ARG D 2 49  ? 148.981 121.026 163.800 1.00 116.05 ?  420 ARG E C     1 
ATOM 6429 O O     . ARG D 2 49  ? 148.361 122.090 163.692 1.00 116.05 ?  420 ARG E O     1 
ATOM 6430 C CB    . ARG D 2 49  ? 151.400 120.803 163.206 1.00 116.05 ?  420 ARG E CB    1 
ATOM 6431 C CG    . ARG D 2 49  ? 152.864 120.770 163.618 1.00 116.05 ?  420 ARG E CG    1 
ATOM 6432 C CD    . ARG D 2 49  ? 153.175 121.795 164.698 1.00 116.05 ?  420 ARG E CD    1 
ATOM 6433 N NE    . ARG D 2 49  ? 153.557 123.081 164.125 1.00 116.05 ?  420 ARG E NE    1 
ATOM 6434 C CZ    . ARG D 2 49  ? 154.689 123.313 163.472 1.00 116.05 ?  420 ARG E CZ    1 
ATOM 6435 N NH1   . ARG D 2 49  ? 155.600 122.368 163.303 1.00 116.05 1  420 ARG E NH1   1 
ATOM 6436 N NH2   . ARG D 2 49  ? 154.917 124.529 162.984 1.00 116.05 ?  420 ARG E NH2   1 
ATOM 6437 N N     . LEU D 2 50  ? 148.445 119.854 163.454 1.00 108.91 ?  421 LEU E N     1 
ATOM 6438 C CA    . LEU D 2 50  ? 147.123 119.809 162.837 1.00 108.91 ?  421 LEU E CA    1 
ATOM 6439 C C     . LEU D 2 50  ? 146.035 120.238 163.811 1.00 108.91 ?  421 LEU E C     1 
ATOM 6440 O O     . LEU D 2 50  ? 144.940 120.620 163.384 1.00 108.91 ?  421 LEU E O     1 
ATOM 6441 C CB    . LEU D 2 50  ? 146.827 118.408 162.292 1.00 108.91 ?  421 LEU E CB    1 
ATOM 6442 C CG    . LEU D 2 50  ? 147.562 117.810 161.080 1.00 108.91 ?  421 LEU E CG    1 
ATOM 6443 C CD1   . LEU D 2 50  ? 149.070 118.039 161.072 1.00 108.91 ?  421 LEU E CD1   1 
ATOM 6444 C CD2   . LEU D 2 50  ? 147.253 116.322 160.970 1.00 108.91 ?  421 LEU E CD2   1 
ATOM 6445 N N     . PHE D 2 51  ? 146.314 120.182 165.114 1.00 111.07 ?  422 PHE E N     1 
ATOM 6446 C CA    . PHE D 2 51  ? 145.357 120.668 166.099 1.00 111.07 ?  422 PHE E CA    1 
ATOM 6447 C C     . PHE D 2 51  ? 145.121 122.166 165.976 1.00 111.07 ?  422 PHE E C     1 
ATOM 6448 O O     . PHE D 2 51  ? 143.981 122.617 166.125 1.00 111.07 ?  422 PHE E O     1 
ATOM 6449 C CB    . PHE D 2 51  ? 145.844 120.338 167.510 1.00 111.07 ?  422 PHE E CB    1 
ATOM 6450 C CG    . PHE D 2 51  ? 144.758 120.350 168.545 1.00 111.07 ?  422 PHE E CG    1 
ATOM 6451 C CD1   . PHE D 2 51  ? 143.424 120.318 168.173 1.00 111.07 ?  422 PHE E CD1   1 
ATOM 6452 C CD2   . PHE D 2 51  ? 145.071 120.407 169.891 1.00 111.07 ?  422 PHE E CD2   1 
ATOM 6453 C CE1   . PHE D 2 51  ? 142.424 120.332 169.125 1.00 111.07 ?  422 PHE E CE1   1 
ATOM 6454 C CE2   . PHE D 2 51  ? 144.075 120.424 170.848 1.00 111.07 ?  422 PHE E CE2   1 
ATOM 6455 C CZ    . PHE D 2 51  ? 142.750 120.386 170.464 1.00 111.07 ?  422 PHE E CZ    1 
ATOM 6456 N N     . GLN D 2 52  ? 146.165 122.943 165.701 1.00 115.80 ?  423 GLN E N     1 
ATOM 6457 C CA    . GLN D 2 52  ? 146.048 124.392 165.629 1.00 115.80 ?  423 GLN E CA    1 
ATOM 6458 C C     . GLN D 2 52  ? 145.544 124.887 164.282 1.00 115.80 ?  423 GLN E C     1 
ATOM 6459 O O     . GLN D 2 52  ? 145.267 126.083 164.145 1.00 115.80 ?  423 GLN E O     1 
ATOM 6460 C CB    . GLN D 2 52  ? 147.399 125.045 165.936 1.00 115.80 ?  423 GLN E CB    1 
ATOM 6461 C CG    . GLN D 2 52  ? 147.895 124.867 167.371 1.00 115.80 ?  423 GLN E CG    1 
ATOM 6462 C CD    . GLN D 2 52  ? 146.783 124.896 168.408 1.00 115.80 ?  423 GLN E CD    1 
ATOM 6463 O OE1   . GLN D 2 52  ? 146.091 123.900 168.632 1.00 115.80 ?  423 GLN E OE1   1 
ATOM 6464 N NE2   . GLN D 2 52  ? 146.606 126.046 169.048 1.00 115.80 ?  423 GLN E NE2   1 
ATOM 6465 N N     . ARG D 2 53  ? 145.417 124.010 163.294 1.00 113.93 ?  424 ARG E N     1 
ATOM 6466 C CA    . ARG D 2 53  ? 144.890 124.379 161.991 1.00 113.93 ?  424 ARG E CA    1 
ATOM 6467 C C     . ARG D 2 53  ? 143.391 124.100 161.939 1.00 113.93 ?  424 ARG E C     1 
ATOM 6468 O O     . ARG D 2 53  ? 142.845 123.337 162.740 1.00 113.93 ?  424 ARG E O     1 
ATOM 6469 C CB    . ARG D 2 53  ? 145.626 123.624 160.879 1.00 113.93 ?  424 ARG E CB    1 
ATOM 6470 C CG    . ARG D 2 53  ? 145.495 124.256 159.501 1.00 113.93 ?  424 ARG E CG    1 
ATOM 6471 C CD    . ARG D 2 53  ? 146.465 125.413 159.331 1.00 113.93 ?  424 ARG E CD    1 
ATOM 6472 N NE    . ARG D 2 53  ? 146.149 126.223 158.161 1.00 113.93 ?  424 ARG E NE    1 
ATOM 6473 C CZ    . ARG D 2 53  ? 146.727 127.381 157.874 1.00 113.93 ?  424 ARG E CZ    1 
ATOM 6474 N NH1   . ARG D 2 53  ? 147.667 127.896 158.650 1.00 113.93 1  424 ARG E NH1   1 
ATOM 6475 N NH2   . ARG D 2 53  ? 146.354 128.040 156.781 1.00 113.93 ?  424 ARG E NH2   1 
ATOM 6476 N N     . LYS D 2 54  ? 142.725 124.741 160.983 1.00 107.93 ?  425 LYS E N     1 
ATOM 6477 C CA    . LYS D 2 54  ? 141.288 124.575 160.828 1.00 107.93 ?  425 LYS E CA    1 
ATOM 6478 C C     . LYS D 2 54  ? 140.947 123.136 160.455 1.00 107.93 ?  425 LYS E C     1 
ATOM 6479 O O     . LYS D 2 54  ? 141.714 122.443 159.780 1.00 107.93 ?  425 LYS E O     1 
ATOM 6480 C CB    . LYS D 2 54  ? 140.755 125.540 159.769 1.00 107.93 ?  425 LYS E CB    1 
ATOM 6481 C CG    . LYS D 2 54  ? 141.198 125.220 158.352 1.00 107.93 ?  425 LYS E CG    1 
ATOM 6482 C CD    . LYS D 2 54  ? 141.610 126.478 157.604 1.00 107.93 ?  425 LYS E CD    1 
ATOM 6483 C CE    . LYS D 2 54  ? 142.849 127.109 158.222 1.00 107.93 ?  425 LYS E CE    1 
ATOM 6484 N NZ    . LYS D 2 54  ? 143.377 128.232 157.398 1.00 107.93 1  425 LYS E NZ    1 
ATOM 6485 N N     . LEU D 2 55  ? 139.784 122.684 160.916 1.00 94.99  ?  426 LEU E N     1 
ATOM 6486 C CA    . LEU D 2 55  ? 139.346 121.304 160.715 1.00 94.99  ?  426 LEU E CA    1 
ATOM 6487 C C     . LEU D 2 55  ? 138.827 121.160 159.291 1.00 94.99  ?  426 LEU E C     1 
ATOM 6488 O O     . LEU D 2 55  ? 137.667 121.447 158.994 1.00 94.99  ?  426 LEU E O     1 
ATOM 6489 C CB    . LEU D 2 55  ? 138.281 120.926 161.737 1.00 94.99  ?  426 LEU E CB    1 
ATOM 6490 C CG    . LEU D 2 55  ? 137.741 119.498 161.661 1.00 94.99  ?  426 LEU E CG    1 
ATOM 6491 C CD1   . LEU D 2 55  ? 138.814 118.501 162.061 1.00 94.99  ?  426 LEU E CD1   1 
ATOM 6492 C CD2   . LEU D 2 55  ? 136.507 119.344 162.535 1.00 94.99  ?  426 LEU E CD2   1 
ATOM 6493 N N     . SER D 2 56  ? 139.702 120.707 158.396 1.00 90.86  ?  427 SER E N     1 
ATOM 6494 C CA    . SER D 2 56  ? 139.329 120.507 157.004 1.00 90.86  ?  427 SER E CA    1 
ATOM 6495 C C     . SER D 2 56  ? 140.306 119.533 156.365 1.00 90.86  ?  427 SER E C     1 
ATOM 6496 O O     . SER D 2 56  ? 141.389 119.274 156.896 1.00 90.86  ?  427 SER E O     1 
ATOM 6497 C CB    . SER D 2 56  ? 139.310 121.828 156.230 1.00 90.86  ?  427 SER E CB    1 
ATOM 6498 O OG    . SER D 2 56  ? 140.594 122.128 155.713 1.00 90.86  ?  427 SER E OG    1 
ATOM 6499 N N     . TRP D 2 57  ? 139.907 118.999 155.215 1.00 86.54  ?  428 TRP E N     1 
ATOM 6500 C CA    . TRP D 2 57  ? 140.780 118.112 154.461 1.00 86.54  ?  428 TRP E CA    1 
ATOM 6501 C C     . TRP D 2 57  ? 141.976 118.887 153.923 1.00 86.54  ?  428 TRP E C     1 
ATOM 6502 O O     . TRP D 2 57  ? 141.851 120.040 153.503 1.00 86.54  ?  428 TRP E O     1 
ATOM 6503 C CB    . TRP D 2 57  ? 140.017 117.462 153.309 1.00 86.54  ?  428 TRP E CB    1 
ATOM 6504 C CG    . TRP D 2 57  ? 139.060 116.396 153.740 1.00 86.54  ?  428 TRP E CG    1 
ATOM 6505 C CD1   . TRP D 2 57  ? 137.716 116.530 153.928 1.00 86.54  ?  428 TRP E CD1   1 
ATOM 6506 C CD2   . TRP D 2 57  ? 139.372 115.032 154.040 1.00 86.54  ?  428 TRP E CD2   1 
ATOM 6507 N NE1   . TRP D 2 57  ? 137.171 115.334 154.321 1.00 86.54  ?  428 TRP E NE1   1 
ATOM 6508 C CE2   . TRP D 2 57  ? 138.168 114.398 154.401 1.00 86.54  ?  428 TRP E CE2   1 
ATOM 6509 C CE3   . TRP D 2 57  ? 140.553 114.285 154.039 1.00 86.54  ?  428 TRP E CE3   1 
ATOM 6510 C CZ2   . TRP D 2 57  ? 138.110 113.054 154.755 1.00 86.54  ?  428 TRP E CZ2   1 
ATOM 6511 C CZ3   . TRP D 2 57  ? 140.493 112.951 154.391 1.00 86.54  ?  428 TRP E CZ3   1 
ATOM 6512 C CH2   . TRP D 2 57  ? 139.281 112.349 154.744 1.00 86.54  ?  428 TRP E CH2   1 
ATOM 6513 N N     . ILE D 2 58  ? 143.143 118.249 153.943 1.00 86.26  ?  429 ILE E N     1 
ATOM 6514 C CA    . ILE D 2 58  ? 144.384 118.869 153.496 1.00 86.26  ?  429 ILE E CA    1 
ATOM 6515 C C     . ILE D 2 58  ? 145.129 117.881 152.610 1.00 86.26  ?  429 ILE E C     1 
ATOM 6516 O O     . ILE D 2 58  ? 145.287 116.710 152.974 1.00 86.26  ?  429 ILE E O     1 
ATOM 6517 C CB    . ILE D 2 58  ? 145.257 119.311 154.686 1.00 86.26  ?  429 ILE E CB    1 
ATOM 6518 C CG1   . ILE D 2 58  ? 146.690 119.591 154.235 1.00 86.26  ?  429 ILE E CG1   1 
ATOM 6519 C CG2   . ILE D 2 58  ? 145.230 118.264 155.788 1.00 86.26  ?  429 ILE E CG2   1 
ATOM 6520 C CD1   . ILE D 2 58  ? 147.570 120.130 155.338 1.00 86.26  ?  429 ILE E CD1   1 
ATOM 6521 N N     . LYS D 2 59  ? 145.577 118.351 151.446 1.00 91.45  ?  430 LYS E N     1 
ATOM 6522 C CA    . LYS D 2 59  ? 146.294 117.492 150.514 1.00 91.45  ?  430 LYS E CA    1 
ATOM 6523 C C     . LYS D 2 59  ? 147.628 117.052 151.102 1.00 91.45  ?  430 LYS E C     1 
ATOM 6524 O O     . LYS D 2 59  ? 148.282 117.802 151.831 1.00 91.45  ?  430 LYS E O     1 
ATOM 6525 C CB    . LYS D 2 59  ? 146.525 118.222 149.191 1.00 91.45  ?  430 LYS E CB    1 
ATOM 6526 C CG    . LYS D 2 59  ? 145.263 118.517 148.402 1.00 91.45  ?  430 LYS E CG    1 
ATOM 6527 C CD    . LYS D 2 59  ? 145.605 119.013 147.007 1.00 91.45  ?  430 LYS E CD    1 
ATOM 6528 C CE    . LYS D 2 59  ? 144.356 119.357 146.216 1.00 91.45  ?  430 LYS E CE    1 
ATOM 6529 N NZ    . LYS D 2 59  ? 144.691 119.949 144.892 1.00 91.45  1  430 LYS E NZ    1 
ATOM 6530 N N     . MET D 2 60  ? 148.032 115.822 150.773 1.00 99.31  ?  431 MET E N     1 
ATOM 6531 C CA    . MET D 2 60  ? 149.305 115.304 151.265 1.00 99.31  ?  431 MET E CA    1 
ATOM 6532 C C     . MET D 2 60  ? 150.489 116.082 150.712 1.00 99.31  ?  431 MET E C     1 
ATOM 6533 O O     . MET D 2 60  ? 151.526 116.189 151.377 1.00 99.31  ?  431 MET E O     1 
ATOM 6534 C CB    . MET D 2 60  ? 149.437 113.819 150.923 1.00 99.31  ?  431 MET E CB    1 
ATOM 6535 C CG    . MET D 2 60  ? 150.105 112.971 152.004 1.00 99.31  ?  431 MET E CG    1 
ATOM 6536 S SD    . MET D 2 60  ? 149.415 113.016 153.677 1.00 99.31  ?  431 MET E SD    1 
ATOM 6537 C CE    . MET D 2 60  ? 147.662 113.248 153.394 1.00 99.31  ?  431 MET E CE    1 
ATOM 6538 N N     . THR D 2 61  ? 150.361 116.631 149.505 1.00 102.09 ?  432 THR E N     1 
ATOM 6539 C CA    . THR D 2 61  ? 151.462 117.377 148.910 1.00 102.09 ?  432 THR E CA    1 
ATOM 6540 C C     . THR D 2 61  ? 151.652 118.747 149.549 1.00 102.09 ?  432 THR E C     1 
ATOM 6541 O O     . THR D 2 61  ? 152.642 119.422 149.247 1.00 102.09 ?  432 THR E O     1 
ATOM 6542 C CB    . THR D 2 61  ? 151.239 117.540 147.406 1.00 102.09 ?  432 THR E CB    1 
ATOM 6543 O OG1   . THR D 2 61  ? 150.471 118.725 147.162 1.00 102.09 ?  432 THR E OG1   1 
ATOM 6544 C CG2   . THR D 2 61  ? 150.496 116.337 146.847 1.00 102.09 ?  432 THR E CG2   1 
ATOM 6545 N N     . LYS D 2 62  ? 150.736 119.174 150.415 1.00 105.97 ?  433 LYS E N     1 
ATOM 6546 C CA    . LYS D 2 62  ? 150.760 120.523 150.962 1.00 105.97 ?  433 LYS E CA    1 
ATOM 6547 C C     . LYS D 2 62  ? 151.349 120.609 152.365 1.00 105.97 ?  433 LYS E C     1 
ATOM 6548 O O     . LYS D 2 62  ? 151.397 121.707 152.928 1.00 105.97 ?  433 LYS E O     1 
ATOM 6549 C CB    . LYS D 2 62  ? 149.347 121.116 150.959 1.00 105.97 ?  433 LYS E CB    1 
ATOM 6550 C CG    . LYS D 2 62  ? 148.675 121.107 149.595 1.00 105.97 ?  433 LYS E CG    1 
ATOM 6551 C CD    . LYS D 2 62  ? 149.602 121.642 148.512 1.00 105.97 ?  433 LYS E CD    1 
ATOM 6552 C CE    . LYS D 2 62  ? 149.851 123.134 148.674 1.00 105.97 ?  433 LYS E CE    1 
ATOM 6553 N NZ    . LYS D 2 62  ? 150.972 123.605 147.815 1.00 105.97 1  433 LYS E NZ    1 
ATOM 6554 N N     . LEU D 2 63  ? 151.796 119.500 152.946 1.00 111.20 ?  434 LEU E N     1 
ATOM 6555 C CA    . LEU D 2 63  ? 152.484 119.528 154.231 1.00 111.20 ?  434 LEU E CA    1 
ATOM 6556 C C     . LEU D 2 63  ? 153.983 119.417 153.992 1.00 111.20 ?  434 LEU E C     1 
ATOM 6557 O O     . LEU D 2 63  ? 154.454 118.430 153.417 1.00 111.20 ?  434 LEU E O     1 
ATOM 6558 C CB    . LEU D 2 63  ? 152.013 118.411 155.164 1.00 111.20 ?  434 LEU E CB    1 
ATOM 6559 C CG    . LEU D 2 63  ? 150.533 118.042 155.245 1.00 111.20 ?  434 LEU E CG    1 
ATOM 6560 C CD1   . LEU D 2 63  ? 150.192 116.970 154.238 1.00 111.20 ?  434 LEU E CD1   1 
ATOM 6561 C CD2   . LEU D 2 63  ? 150.175 117.591 156.651 1.00 111.20 ?  434 LEU E CD2   1 
ATOM 6562 N N     . GLU D 2 64  ? 154.727 120.430 154.434 1.00 121.60 ?  435 GLU E N     1 
ATOM 6563 C CA    . GLU D 2 64  ? 156.186 120.457 154.337 1.00 121.60 ?  435 GLU E CA    1 
ATOM 6564 C C     . GLU D 2 64  ? 156.711 120.770 155.733 1.00 121.60 ?  435 GLU E C     1 
ATOM 6565 O O     . GLU D 2 64  ? 156.954 121.932 156.071 1.00 121.60 ?  435 GLU E O     1 
ATOM 6566 C CB    . GLU D 2 64  ? 156.659 121.480 153.307 1.00 121.60 ?  435 GLU E CB    1 
ATOM 6567 C CG    . GLU D 2 64  ? 156.138 121.241 151.899 1.00 121.60 ?  435 GLU E CG    1 
ATOM 6568 C CD    . GLU D 2 64  ? 154.760 121.833 151.681 1.00 121.60 ?  435 GLU E CD    1 
ATOM 6569 O OE1   . GLU D 2 64  ? 154.404 122.793 152.397 1.00 121.60 ?  435 GLU E OE1   1 
ATOM 6570 O OE2   . GLU D 2 64  ? 154.032 121.339 150.795 1.00 121.60 -1 435 GLU E OE2   1 
ATOM 6571 N N     . TYR D 2 65  ? 156.883 119.731 156.543 1.00 126.62 ?  436 TYR E N     1 
ATOM 6572 C CA    . TYR D 2 65  ? 157.358 119.863 157.917 1.00 126.62 ?  436 TYR E CA    1 
ATOM 6573 C C     . TYR D 2 65  ? 158.722 119.183 157.995 1.00 126.62 ?  436 TYR E C     1 
ATOM 6574 O O     . TYR D 2 65  ? 158.832 118.015 158.370 1.00 126.62 ?  436 TYR E O     1 
ATOM 6575 C CB    . TYR D 2 65  ? 156.364 119.250 158.896 1.00 126.62 ?  436 TYR E CB    1 
ATOM 6576 C CG    . TYR D 2 65  ? 155.139 120.099 159.148 1.00 126.62 ?  436 TYR E CG    1 
ATOM 6577 C CD1   . TYR D 2 65  ? 155.019 121.367 158.594 1.00 126.62 ?  436 TYR E CD1   1 
ATOM 6578 C CD2   . TYR D 2 65  ? 154.096 119.627 159.932 1.00 126.62 ?  436 TYR E CD2   1 
ATOM 6579 C CE1   . TYR D 2 65  ? 153.898 122.143 158.821 1.00 126.62 ?  436 TYR E CE1   1 
ATOM 6580 C CE2   . TYR D 2 65  ? 152.973 120.393 160.161 1.00 126.62 ?  436 TYR E CE2   1 
ATOM 6581 C CZ    . TYR D 2 65  ? 152.879 121.650 159.607 1.00 126.62 ?  436 TYR E CZ    1 
ATOM 6582 O OH    . TYR D 2 65  ? 151.759 122.417 159.837 1.00 126.62 ?  436 TYR E OH    1 
ATOM 6583 N N     . GLU D 2 66  ? 159.768 119.934 157.646 1.00 131.63 ?  437 GLU E N     1 
ATOM 6584 C CA    . GLU D 2 66  ? 161.116 119.379 157.654 1.00 131.63 ?  437 GLU E CA    1 
ATOM 6585 C C     . GLU D 2 66  ? 161.656 119.238 159.070 1.00 131.63 ?  437 GLU E C     1 
ATOM 6586 O O     . GLU D 2 66  ? 162.579 118.450 159.305 1.00 131.63 ?  437 GLU E O     1 
ATOM 6587 C CB    . GLU D 2 66  ? 162.068 120.244 156.817 1.00 131.63 ?  437 GLU E CB    1 
ATOM 6588 C CG    . GLU D 2 66  ? 162.185 121.743 157.183 1.00 131.63 ?  437 GLU E CG    1 
ATOM 6589 C CD    . GLU D 2 66  ? 160.875 122.525 157.178 1.00 131.63 ?  437 GLU E CD    1 
ATOM 6590 O OE1   . GLU D 2 66  ? 160.889 123.695 157.616 1.00 131.63 ?  437 GLU E OE1   1 
ATOM 6591 O OE2   . GLU D 2 66  ? 159.844 121.996 156.712 1.00 131.63 -1 437 GLU E OE2   1 
ATOM 6592 N N     . GLU D 2 67  ? 161.099 119.988 160.023 1.00 129.53 ?  438 GLU E N     1 
ATOM 6593 C CA    . GLU D 2 67  ? 161.605 119.957 161.390 1.00 129.53 ?  438 GLU E CA    1 
ATOM 6594 C C     . GLU D 2 67  ? 161.283 118.652 162.103 1.00 129.53 ?  438 GLU E C     1 
ATOM 6595 O O     . GLU D 2 67  ? 161.916 118.345 163.118 1.00 129.53 ?  438 GLU E O     1 
ATOM 6596 C CB    . GLU D 2 67  ? 161.042 121.135 162.188 1.00 129.53 ?  438 GLU E CB    1 
ATOM 6597 C CG    . GLU D 2 67  ? 159.616 120.935 162.685 1.00 129.53 ?  438 GLU E CG    1 
ATOM 6598 C CD    . GLU D 2 67  ? 158.589 120.966 161.568 1.00 129.53 ?  438 GLU E CD    1 
ATOM 6599 O OE1   . GLU D 2 67  ? 158.925 121.421 160.455 1.00 129.53 ?  438 GLU E OE1   1 
ATOM 6600 O OE2   . GLU D 2 67  ? 157.442 120.532 161.806 1.00 129.53 -1 438 GLU E OE2   1 
ATOM 6601 N N     . ILE D 2 68  ? 160.320 117.879 161.605 1.00 125.63 ?  439 ILE E N     1 
ATOM 6602 C CA    . ILE D 2 68  ? 159.930 116.640 162.266 1.00 125.63 ?  439 ILE E CA    1 
ATOM 6603 C C     . ILE D 2 68  ? 160.377 115.435 161.445 1.00 125.63 ?  439 ILE E C     1 
ATOM 6604 O O     . ILE D 2 68  ? 160.976 114.497 161.985 1.00 125.63 ?  439 ILE E O     1 
ATOM 6605 C CB    . ILE D 2 68  ? 158.412 116.610 162.541 1.00 125.63 ?  439 ILE E CB    1 
ATOM 6606 C CG1   . ILE D 2 68  ? 158.012 115.279 163.175 1.00 125.63 ?  439 ILE E CG1   1 
ATOM 6607 C CG2   . ILE D 2 68  ? 157.608 116.905 161.281 1.00 125.63 ?  439 ILE E CG2   1 
ATOM 6608 C CD1   . ILE D 2 68  ? 158.626 115.056 164.531 1.00 125.63 ?  439 ILE E CD1   1 
ATOM 6609 N N     . ALA D 2 69  ? 160.106 115.453 160.141 1.00 126.73 ?  440 ALA E N     1 
ATOM 6610 C CA    . ALA D 2 69  ? 160.481 114.351 159.267 1.00 126.73 ?  440 ALA E CA    1 
ATOM 6611 C C     . ALA D 2 69  ? 160.354 114.800 157.820 1.00 126.73 ?  440 ALA E C     1 
ATOM 6612 O O     . ALA D 2 69  ? 159.362 115.431 157.446 1.00 126.73 ?  440 ALA E O     1 
ATOM 6613 C CB    . ALA D 2 69  ? 159.609 113.114 159.513 1.00 126.73 ?  440 ALA E CB    1 
ATOM 6614 N N     . LEU D 2 70  ? 161.363 114.467 157.012 1.00 126.56 ?  441 LEU E N     1 
ATOM 6615 C CA    . LEU D 2 70  ? 161.301 114.782 155.588 1.00 126.56 ?  441 LEU E CA    1 
ATOM 6616 C C     . LEU D 2 70  ? 160.188 114.002 154.901 1.00 126.56 ?  441 LEU E C     1 
ATOM 6617 O O     . LEU D 2 70  ? 159.465 114.547 154.058 1.00 126.56 ?  441 LEU E O     1 
ATOM 6618 C CB    . LEU D 2 70  ? 162.648 114.497 154.923 1.00 126.56 ?  441 LEU E CB    1 
ATOM 6619 C CG    . LEU D 2 70  ? 163.687 115.623 154.881 1.00 126.56 ?  441 LEU E CG    1 
ATOM 6620 C CD1   . LEU D 2 70  ? 163.330 116.634 153.800 1.00 126.56 ?  441 LEU E CD1   1 
ATOM 6621 C CD2   . LEU D 2 70  ? 163.844 116.311 156.231 1.00 126.56 ?  441 LEU E CD2   1 
ATOM 6622 N N     . ASP D 2 71  ? 160.034 112.727 155.247 1.00 127.78 ?  442 ASP E N     1 
ATOM 6623 C CA    . ASP D 2 71  ? 158.972 111.879 154.716 1.00 127.78 ?  442 ASP E CA    1 
ATOM 6624 C C     . ASP D 2 71  ? 157.995 111.589 155.849 1.00 127.78 ?  442 ASP E C     1 
ATOM 6625 O O     . ASP D 2 71  ? 158.335 110.882 156.803 1.00 127.78 ?  442 ASP E O     1 
ATOM 6626 C CB    . ASP D 2 71  ? 159.541 110.588 154.133 1.00 127.78 ?  442 ASP E CB    1 
ATOM 6627 C CG    . ASP D 2 71  ? 158.484 109.741 153.456 1.00 127.78 ?  442 ASP E CG    1 
ATOM 6628 O OD1   . ASP D 2 71  ? 157.467 110.311 153.009 1.00 127.78 ?  442 ASP E OD1   1 
ATOM 6629 O OD2   . ASP D 2 71  ? 158.667 108.509 153.373 1.00 127.78 -1 442 ASP E OD2   1 
ATOM 6630 N N     . LEU D 2 72  ? 156.787 112.133 155.741 1.00 124.31 ?  443 LEU E N     1 
ATOM 6631 C CA    . LEU D 2 72  ? 155.792 112.021 156.796 1.00 124.31 ?  443 LEU E CA    1 
ATOM 6632 C C     . LEU D 2 72  ? 154.889 110.805 156.647 1.00 124.31 ?  443 LEU E C     1 
ATOM 6633 O O     . LEU D 2 72  ? 154.141 110.496 157.581 1.00 124.31 ?  443 LEU E O     1 
ATOM 6634 C CB    . LEU D 2 72  ? 154.933 113.289 156.843 1.00 124.31 ?  443 LEU E CB    1 
ATOM 6635 C CG    . LEU D 2 72  ? 155.654 114.585 157.212 1.00 124.31 ?  443 LEU E CG    1 
ATOM 6636 C CD1   . LEU D 2 72  ? 154.715 115.774 157.086 1.00 124.31 ?  443 LEU E CD1   1 
ATOM 6637 C CD2   . LEU D 2 72  ? 156.230 114.498 158.616 1.00 124.31 ?  443 LEU E CD2   1 
ATOM 6638 N N     . THR D 2 73  ? 154.941 110.107 155.510 1.00 124.94 ?  444 THR E N     1 
ATOM 6639 C CA    . THR D 2 73  ? 154.028 108.986 155.289 1.00 124.94 ?  444 THR E CA    1 
ATOM 6640 C C     . THR D 2 73  ? 154.133 107.898 156.354 1.00 124.94 ?  444 THR E C     1 
ATOM 6641 O O     . THR D 2 73  ? 153.080 107.398 156.787 1.00 124.94 ?  444 THR E O     1 
ATOM 6642 C CB    . THR D 2 73  ? 154.217 108.423 153.873 1.00 124.94 ?  444 THR E CB    1 
ATOM 6643 O OG1   . THR D 2 73  ? 155.367 107.571 153.817 1.00 124.94 ?  444 THR E OG1   1 
ATOM 6644 C CG2   . THR D 2 73  ? 154.371 109.553 152.866 1.00 124.94 ?  444 THR E CG2   1 
ATOM 6645 N N     . PRO D 2 74  ? 155.320 107.477 156.821 1.00 122.14 ?  445 PRO E N     1 
ATOM 6646 C CA    . PRO D 2 74  ? 155.328 106.499 157.924 1.00 122.14 ?  445 PRO E CA    1 
ATOM 6647 C C     . PRO D 2 74  ? 154.665 107.025 159.183 1.00 122.14 ?  445 PRO E C     1 
ATOM 6648 O O     . PRO D 2 74  ? 154.031 106.257 159.918 1.00 122.14 ?  445 PRO E O     1 
ATOM 6649 C CB    . PRO D 2 74  ? 156.822 106.219 158.138 1.00 122.14 ?  445 PRO E CB    1 
ATOM 6650 C CG    . PRO D 2 74  ? 157.506 107.422 157.627 1.00 122.14 ?  445 PRO E CG    1 
ATOM 6651 C CD    . PRO D 2 74  ? 156.694 107.879 156.459 1.00 122.14 ?  445 PRO E CD    1 
ATOM 6652 N N     . VAL D 2 75  ? 154.794 108.326 159.451 1.00 119.94 ?  446 VAL E N     1 
ATOM 6653 C CA    . VAL D 2 75  ? 154.185 108.904 160.644 1.00 119.94 ?  446 VAL E CA    1 
ATOM 6654 C C     . VAL D 2 75  ? 152.668 108.918 160.526 1.00 119.94 ?  446 VAL E C     1 
ATOM 6655 O O     . VAL D 2 75  ? 151.962 108.638 161.503 1.00 119.94 ?  446 VAL E O     1 
ATOM 6656 C CB    . VAL D 2 75  ? 154.742 110.317 160.895 1.00 119.94 ?  446 VAL E CB    1 
ATOM 6657 C CG1   . VAL D 2 75  ? 154.510 110.728 162.340 1.00 119.94 ?  446 VAL E CG1   1 
ATOM 6658 C CG2   . VAL D 2 75  ? 156.220 110.375 160.544 1.00 119.94 ?  446 VAL E CG2   1 
ATOM 6659 N N     . ILE D 2 76  ? 152.140 109.241 159.343 1.00 120.30 ?  447 ILE E N     1 
ATOM 6660 C CA    . ILE D 2 76  ? 150.691 109.314 159.165 1.00 120.30 ?  447 ILE E CA    1 
ATOM 6661 C C     . ILE D 2 76  ? 150.048 107.961 159.434 1.00 120.30 ?  447 ILE E C     1 
ATOM 6662 O O     . ILE D 2 76  ? 148.984 107.877 160.060 1.00 120.30 ?  447 ILE E O     1 
ATOM 6663 C CB    . ILE D 2 76  ? 150.349 109.836 157.758 1.00 120.30 ?  447 ILE E CB    1 
ATOM 6664 C CG1   . ILE D 2 76  ? 151.012 111.193 157.519 1.00 120.30 ?  447 ILE E CG1   1 
ATOM 6665 C CG2   . ILE D 2 76  ? 148.844 109.934 157.575 1.00 120.30 ?  447 ILE E CG2   1 
ATOM 6666 C CD1   . ILE D 2 76  ? 151.434 111.421 156.091 1.00 120.30 ?  447 ILE E CD1   1 
ATOM 6667 N N     . GLU D 2 77  ? 150.679 106.881 158.965 1.00 123.16 ?  448 GLU E N     1 
ATOM 6668 C CA    . GLU D 2 77  ? 150.162 105.547 159.251 1.00 123.16 ?  448 GLU E CA    1 
ATOM 6669 C C     . GLU D 2 77  ? 150.108 105.278 160.748 1.00 123.16 ?  448 GLU E C     1 
ATOM 6670 O O     . GLU D 2 77  ? 149.200 104.587 161.221 1.00 123.16 ?  448 GLU E O     1 
ATOM 6671 C CB    . GLU D 2 77  ? 151.016 104.488 158.554 1.00 123.16 ?  448 GLU E CB    1 
ATOM 6672 C CG    . GLU D 2 77  ? 151.208 104.722 157.067 1.00 123.16 ?  448 GLU E CG    1 
ATOM 6673 C CD    . GLU D 2 77  ? 152.625 104.435 156.615 1.00 123.16 ?  448 GLU E CD    1 
ATOM 6674 O OE1   . GLU D 2 77  ? 153.391 103.840 157.401 1.00 123.16 ?  448 GLU E OE1   1 
ATOM 6675 O OE2   . GLU D 2 77  ? 152.973 104.806 155.474 1.00 123.16 -1 448 GLU E OE2   1 
ATOM 6676 N N     . GLU D 2 78  ? 151.067 105.815 161.506 1.00 120.47 ?  449 GLU E N     1 
ATOM 6677 C CA    . GLU D 2 78  ? 151.061 105.626 162.953 1.00 120.47 ?  449 GLU E CA    1 
ATOM 6678 C C     . GLU D 2 78  ? 149.820 106.244 163.585 1.00 120.47 ?  449 GLU E C     1 
ATOM 6679 O O     . GLU D 2 78  ? 149.194 105.639 164.463 1.00 120.47 ?  449 GLU E O     1 
ATOM 6680 C CB    . GLU D 2 78  ? 152.331 106.219 163.561 1.00 120.47 ?  449 GLU E CB    1 
ATOM 6681 C CG    . GLU D 2 78  ? 152.405 106.125 165.074 1.00 120.47 ?  449 GLU E CG    1 
ATOM 6682 C CD    . GLU D 2 78  ? 153.633 106.813 165.637 1.00 120.47 ?  449 GLU E CD    1 
ATOM 6683 O OE1   . GLU D 2 78  ? 154.365 107.457 164.856 1.00 120.47 ?  449 GLU E OE1   1 
ATOM 6684 O OE2   . GLU D 2 78  ? 153.868 106.710 166.860 1.00 120.47 -1 449 GLU E OE2   1 
ATOM 6685 N N     . LEU D 2 79  ? 149.448 107.450 163.155 1.00 113.70 ?  450 LEU E N     1 
ATOM 6686 C CA    . LEU D 2 79  ? 148.204 108.044 163.631 1.00 113.70 ?  450 LEU E CA    1 
ATOM 6687 C C     . LEU D 2 79  ? 146.983 107.418 162.971 1.00 113.70 ?  450 LEU E C     1 
ATOM 6688 O O     . LEU D 2 79  ? 145.899 107.418 163.564 1.00 113.70 ?  450 LEU E O     1 
ATOM 6689 C CB    . LEU D 2 79  ? 148.201 109.557 163.395 1.00 113.70 ?  450 LEU E CB    1 
ATOM 6690 C CG    . LEU D 2 79  ? 149.146 110.438 164.219 1.00 113.70 ?  450 LEU E CG    1 
ATOM 6691 C CD1   . LEU D 2 79  ? 149.118 110.028 165.685 1.00 113.70 ?  450 LEU E CD1   1 
ATOM 6692 C CD2   . LEU D 2 79  ? 150.566 110.435 163.677 1.00 113.70 ?  450 LEU E CD2   1 
ATOM 6693 N N     . THR D 2 80  ? 147.136 106.888 161.755 1.00 115.22 ?  451 THR E N     1 
ATOM 6694 C CA    . THR D 2 80  ? 145.990 106.338 161.036 1.00 115.22 ?  451 THR E CA    1 
ATOM 6695 C C     . THR D 2 80  ? 145.409 105.130 161.760 1.00 115.22 ?  451 THR E C     1 
ATOM 6696 O O     . THR D 2 80  ? 144.191 105.032 161.946 1.00 115.22 ?  451 THR E O     1 
ATOM 6697 C CB    . THR D 2 80  ? 146.394 105.966 159.610 1.00 115.22 ?  451 THR E CB    1 
ATOM 6698 O OG1   . THR D 2 80  ? 147.133 107.044 159.024 1.00 115.22 ?  451 THR E OG1   1 
ATOM 6699 C CG2   . THR D 2 80  ? 145.161 105.687 158.766 1.00 115.22 ?  451 THR E CG2   1 
ATOM 6700 N N     . ASN D 2 81  ? 146.267 104.197 162.179 1.00 117.25 ?  452 ASN E N     1 
ATOM 6701 C CA    . ASN D 2 81  ? 145.774 103.006 162.864 1.00 117.25 ?  452 ASN E CA    1 
ATOM 6702 C C     . ASN D 2 81  ? 145.285 103.330 164.269 1.00 117.25 ?  452 ASN E C     1 
ATOM 6703 O O     . ASN D 2 81  ? 144.361 102.677 164.768 1.00 117.25 ?  452 ASN E O     1 
ATOM 6704 C CB    . ASN D 2 81  ? 146.862 101.934 162.913 1.00 117.25 ?  452 ASN E CB    1 
ATOM 6705 C CG    . ASN D 2 81  ? 148.232 102.507 163.210 1.00 117.25 ?  452 ASN E CG    1 
ATOM 6706 O OD1   . ASN D 2 81  ? 148.487 102.994 164.311 1.00 117.25 ?  452 ASN E OD1   1 
ATOM 6707 N ND2   . ASN D 2 81  ? 149.122 102.455 162.226 1.00 117.25 ?  452 ASN E ND2   1 
ATOM 6708 N N     . ALA D 2 82  ? 145.886 104.328 164.919 1.00 110.30 ?  453 ALA E N     1 
ATOM 6709 C CA    . ALA D 2 82  ? 145.482 104.704 166.267 1.00 110.30 ?  453 ALA E CA    1 
ATOM 6710 C C     . ALA D 2 82  ? 144.116 105.375 166.311 1.00 110.30 ?  453 ALA E C     1 
ATOM 6711 O O     . ALA D 2 82  ? 143.554 105.522 167.401 1.00 110.30 ?  453 ALA E O     1 
ATOM 6712 C CB    . ALA D 2 82  ? 146.530 105.627 166.889 1.00 110.30 ?  453 ALA E CB    1 
ATOM 6713 N N     . GLY D 2 83  ? 143.572 105.780 165.166 1.00 105.72 ?  454 GLY E N     1 
ATOM 6714 C CA    . GLY D 2 83  ? 142.289 106.443 165.118 1.00 105.72 ?  454 GLY E CA    1 
ATOM 6715 C C     . GLY D 2 83  ? 142.336 107.949 165.242 1.00 105.72 ?  454 GLY E C     1 
ATOM 6716 O O     . GLY D 2 83  ? 141.290 108.597 165.105 1.00 105.72 ?  454 GLY E O     1 
ATOM 6717 N N     . PHE D 2 84  ? 143.510 108.530 165.496 1.00 106.64 ?  455 PHE E N     1 
ATOM 6718 C CA    . PHE D 2 84  ? 143.619 109.981 165.570 1.00 106.64 ?  455 PHE E CA    1 
ATOM 6719 C C     . PHE D 2 84  ? 143.455 110.640 164.209 1.00 106.64 ?  455 PHE E C     1 
ATOM 6720 O O     . PHE D 2 84  ? 143.052 111.805 164.143 1.00 106.64 ?  455 PHE E O     1 
ATOM 6721 C CB    . PHE D 2 84  ? 144.966 110.377 166.176 1.00 106.64 ?  455 PHE E CB    1 
ATOM 6722 C CG    . PHE D 2 84  ? 145.121 109.983 167.615 1.00 106.64 ?  455 PHE E CG    1 
ATOM 6723 C CD1   . PHE D 2 84  ? 146.327 109.494 168.087 1.00 106.64 ?  455 PHE E CD1   1 
ATOM 6724 C CD2   . PHE D 2 84  ? 144.061 110.104 168.497 1.00 106.64 ?  455 PHE E CD2   1 
ATOM 6725 C CE1   . PHE D 2 84  ? 146.472 109.130 169.413 1.00 106.64 ?  455 PHE E CE1   1 
ATOM 6726 C CE2   . PHE D 2 84  ? 144.200 109.742 169.823 1.00 106.64 ?  455 PHE E CE2   1 
ATOM 6727 C CZ    . PHE D 2 84  ? 145.408 109.255 170.281 1.00 106.64 ?  455 PHE E CZ    1 
ATOM 6728 N N     . LEU D 2 85  ? 143.747 109.921 163.128 1.00 104.00 ?  456 LEU E N     1 
ATOM 6729 C CA    . LEU D 2 85  ? 143.654 110.463 161.782 1.00 104.00 ?  456 LEU E CA    1 
ATOM 6730 C C     . LEU D 2 85  ? 142.812 109.532 160.923 1.00 104.00 ?  456 LEU E C     1 
ATOM 6731 O O     . LEU D 2 85  ? 142.708 108.332 161.187 1.00 104.00 ?  456 LEU E O     1 
ATOM 6732 C CB    . LEU D 2 85  ? 145.037 110.643 161.143 1.00 104.00 ?  456 LEU E CB    1 
ATOM 6733 C CG    . LEU D 2 85  ? 145.544 112.070 160.946 1.00 104.00 ?  456 LEU E CG    1 
ATOM 6734 C CD1   . LEU D 2 85  ? 145.472 112.843 162.247 1.00 104.00 ?  456 LEU E CD1   1 
ATOM 6735 C CD2   . LEU D 2 85  ? 146.960 112.063 160.399 1.00 104.00 ?  456 LEU E CD2   1 
ATOM 6736 N N     . GLN D 2 86  ? 142.207 110.106 159.888 1.00 95.95  ?  457 GLN E N     1 
ATOM 6737 C CA    . GLN D 2 86  ? 141.491 109.340 158.882 1.00 95.95  ?  457 GLN E CA    1 
ATOM 6738 C C     . GLN D 2 86  ? 141.953 109.783 157.503 1.00 95.95  ?  457 GLN E C     1 
ATOM 6739 O O     . GLN D 2 86  ? 142.256 110.958 157.279 1.00 95.95  ?  457 GLN E O     1 
ATOM 6740 C CB    . GLN D 2 86  ? 139.971 109.500 159.015 1.00 95.95  ?  457 GLN E CB    1 
ATOM 6741 C CG    . GLN D 2 86  ? 139.463 110.912 158.803 1.00 95.95  ?  457 GLN E CG    1 
ATOM 6742 C CD    . GLN D 2 86  ? 137.979 111.035 159.076 1.00 95.95  ?  457 GLN E CD    1 
ATOM 6743 O OE1   . GLN D 2 86  ? 137.363 110.131 159.639 1.00 95.95  ?  457 GLN E OE1   1 
ATOM 6744 N NE2   . GLN D 2 86  ? 137.394 112.156 158.673 1.00 95.95  ?  457 GLN E NE2   1 
ATOM 6745 N N     . THR D 2 87  ? 142.015 108.830 156.584 1.00 99.23  ?  458 THR E N     1 
ATOM 6746 C CA    . THR D 2 87  ? 142.519 109.070 155.245 1.00 99.23  ?  458 THR E CA    1 
ATOM 6747 C C     . THR D 2 87  ? 141.354 109.244 154.269 1.00 99.23  ?  458 THR E C     1 
ATOM 6748 O O     . THR D 2 87  ? 140.181 109.232 154.655 1.00 99.23  ?  458 THR E O     1 
ATOM 6749 C CB    . THR D 2 87  ? 143.466 107.934 154.841 1.00 99.23  ?  458 THR E CB    1 
ATOM 6750 O OG1   . THR D 2 87  ? 144.402 108.409 153.864 1.00 99.23  ?  458 THR E OG1   1 
ATOM 6751 C CG2   . THR D 2 87  ? 142.696 106.737 154.293 1.00 99.23  ?  458 THR E CG2   1 
ATOM 6752 N N     . GLU D 2 88  ? 141.679 109.408 152.985 1.00 101.41 ?  459 GLU E N     1 
ATOM 6753 C CA    . GLU D 2 88  ? 140.678 109.674 151.960 1.00 101.41 ?  459 GLU E CA    1 
ATOM 6754 C C     . GLU D 2 88  ? 139.714 108.515 151.750 1.00 101.41 ?  459 GLU E C     1 
ATOM 6755 O O     . GLU D 2 88  ? 138.691 108.702 151.083 1.00 101.41 ?  459 GLU E O     1 
ATOM 6756 C CB    . GLU D 2 88  ? 141.367 110.006 150.636 1.00 101.41 ?  459 GLU E CB    1 
ATOM 6757 C CG    . GLU D 2 88  ? 141.799 108.783 149.843 1.00 101.41 ?  459 GLU E CG    1 
ATOM 6758 C CD    . GLU D 2 88  ? 143.046 108.124 150.403 1.00 101.41 ?  459 GLU E CD    1 
ATOM 6759 O OE1   . GLU D 2 88  ? 143.573 108.606 151.427 1.00 101.41 ?  459 GLU E OE1   1 
ATOM 6760 O OE2   . GLU D 2 88  ? 143.498 107.119 149.817 1.00 101.41 -1 459 GLU E OE2   1 
ATOM 6761 N N     . SER D 2 89  ? 140.017 107.329 152.284 1.00 100.01 ?  460 SER E N     1 
ATOM 6762 C CA    . SER D 2 89  ? 139.129 106.185 152.103 1.00 100.01 ?  460 SER E CA    1 
ATOM 6763 C C     . SER D 2 89  ? 137.738 106.459 152.657 1.00 100.01 ?  460 SER E C     1 
ATOM 6764 O O     . SER D 2 89  ? 136.751 105.906 152.157 1.00 100.01 ?  460 SER E O     1 
ATOM 6765 C CB    . SER D 2 89  ? 139.728 104.946 152.768 1.00 100.01 ?  460 SER E CB    1 
ATOM 6766 O OG    . SER D 2 89  ? 139.829 105.121 154.170 1.00 100.01 ?  460 SER E OG    1 
ATOM 6767 N N     . GLU D 2 90  ? 137.635 107.302 153.679 1.00 103.17 ?  461 GLU E N     1 
ATOM 6768 C CA    . GLU D 2 90  ? 136.351 107.665 154.260 1.00 103.17 ?  461 GLU E CA    1 
ATOM 6769 C C     . GLU D 2 90  ? 135.762 108.929 153.650 1.00 103.17 ?  461 GLU E C     1 
ATOM 6770 O O     . GLU D 2 90  ? 134.697 109.373 154.090 1.00 103.17 ?  461 GLU E O     1 
ATOM 6771 C CB    . GLU D 2 90  ? 136.490 107.839 155.775 1.00 103.17 ?  461 GLU E CB    1 
ATOM 6772 C CG    . GLU D 2 90  ? 136.964 106.588 156.496 1.00 103.17 ?  461 GLU E CG    1 
ATOM 6773 C CD    . GLU D 2 90  ? 137.147 106.806 157.985 1.00 103.17 ?  461 GLU E CD    1 
ATOM 6774 O OE1   . GLU D 2 90  ? 136.373 107.591 158.571 1.00 103.17 ?  461 GLU E OE1   1 
ATOM 6775 O OE2   . GLU D 2 90  ? 138.063 106.190 158.570 1.00 103.17 -1 461 GLU E OE2   1 
ATOM 6776 N N     . LEU D 2 91  ? 136.423 109.514 152.655 1.00 95.50  ?  462 LEU E N     1 
ATOM 6777 C CA    . LEU D 2 91  ? 135.944 110.738 152.022 1.00 95.50  ?  462 LEU E CA    1 
ATOM 6778 C C     . LEU D 2 91  ? 134.886 110.372 150.988 1.00 95.50  ?  462 LEU E C     1 
ATOM 6779 O O     . LEU D 2 91  ? 135.210 110.079 149.832 1.00 95.50  ?  462 LEU E O     1 
ATOM 6780 C CB    . LEU D 2 91  ? 137.110 111.491 151.387 1.00 95.50  ?  462 LEU E CB    1 
ATOM 6781 C CG    . LEU D 2 91  ? 136.804 112.751 150.579 1.00 95.50  ?  462 LEU E CG    1 
ATOM 6782 C CD1   . LEU D 2 91  ? 136.087 113.777 151.440 1.00 95.50  ?  462 LEU E CD1   1 
ATOM 6783 C CD2   . LEU D 2 91  ? 138.081 113.329 149.992 1.00 95.50  ?  462 LEU E CD2   1 
ATOM 6784 N N     . GLN D 2 92  ? 133.618 110.388 151.401 1.00 96.82  ?  463 GLN E N     1 
ATOM 6785 C CA    . GLN D 2 92  ? 132.512 110.005 150.534 1.00 96.82  ?  463 GLN E CA    1 
ATOM 6786 C C     . GLN D 2 92  ? 131.599 111.157 150.144 1.00 96.82  ?  463 GLN E C     1 
ATOM 6787 O O     . GLN D 2 92  ? 130.836 111.009 149.184 1.00 96.82  ?  463 GLN E O     1 
ATOM 6788 C CB    . GLN D 2 92  ? 131.646 108.920 151.197 1.00 96.82  ?  463 GLN E CB    1 
ATOM 6789 C CG    . GLN D 2 92  ? 132.341 107.622 151.614 1.00 96.82  ?  463 GLN E CG    1 
ATOM 6790 C CD    . GLN D 2 92  ? 133.427 107.170 150.656 1.00 96.82  ?  463 GLN E CD    1 
ATOM 6791 O OE1   . GLN D 2 92  ? 134.593 107.533 150.797 1.00 96.82  ?  463 GLN E OE1   1 
ATOM 6792 N NE2   . GLN D 2 92  ? 133.043 106.367 149.671 1.00 96.82  ?  463 GLN E NE2   1 
ATOM 6793 N N     . GLU D 2 93  ? 131.646 112.287 150.842 1.00 97.89  ?  464 GLU E N     1 
ATOM 6794 C CA    . GLU D 2 93  ? 130.734 113.390 150.576 1.00 97.89  ?  464 GLU E CA    1 
ATOM 6795 C C     . GLU D 2 93  ? 131.238 114.211 149.398 1.00 97.89  ?  464 GLU E C     1 
ATOM 6796 O O     . GLU D 2 93  ? 132.407 114.608 149.363 1.00 97.89  ?  464 GLU E O     1 
ATOM 6797 C CB    . GLU D 2 93  ? 130.575 114.274 151.812 1.00 97.89  ?  464 GLU E CB    1 
ATOM 6798 C CG    . GLU D 2 93  ? 129.521 113.775 152.783 1.00 97.89  ?  464 GLU E CG    1 
ATOM 6799 C CD    . GLU D 2 93  ? 128.134 113.740 152.169 1.00 97.89  ?  464 GLU E CD    1 
ATOM 6800 O OE1   . GLU D 2 93  ? 127.828 114.615 151.332 1.00 97.89  ?  464 GLU E OE1   1 
ATOM 6801 O OE2   . GLU D 2 93  ? 127.352 112.832 152.520 1.00 97.89  -1 464 GLU E OE2   1 
ATOM 6802 N N     . LEU D 2 94  ? 130.347 114.466 148.438 1.00 91.01  ?  465 LEU E N     1 
ATOM 6803 C CA    . LEU D 2 94  ? 130.736 115.191 147.234 1.00 91.01  ?  465 LEU E CA    1 
ATOM 6804 C C     . LEU D 2 94  ? 131.174 116.614 147.556 1.00 91.01  ?  465 LEU E C     1 
ATOM 6805 O O     . LEU D 2 94  ? 132.154 117.112 146.991 1.00 91.01  ?  465 LEU E O     1 
ATOM 6806 C CB    . LEU D 2 94  ? 129.577 115.201 146.238 1.00 91.01  ?  465 LEU E CB    1 
ATOM 6807 C CG    . LEU D 2 94  ? 129.769 116.037 144.973 1.00 91.01  ?  465 LEU E CG    1 
ATOM 6808 C CD1   . LEU D 2 94  ? 131.028 115.615 144.236 1.00 91.01  ?  465 LEU E CD1   1 
ATOM 6809 C CD2   . LEU D 2 94  ? 128.551 115.922 144.074 1.00 91.01  ?  465 LEU E CD2   1 
ATOM 6810 N N     . SER D 2 95  ? 130.460 117.282 148.465 1.00 90.68  ?  466 SER E N     1 
ATOM 6811 C CA    . SER D 2 95  ? 130.761 118.679 148.763 1.00 90.68  ?  466 SER E CA    1 
ATOM 6812 C C     . SER D 2 95  ? 132.159 118.836 149.343 1.00 90.68  ?  466 SER E C     1 
ATOM 6813 O O     . SER D 2 95  ? 132.864 119.802 149.030 1.00 90.68  ?  466 SER E O     1 
ATOM 6814 C CB    . SER D 2 95  ? 129.717 119.246 149.723 1.00 90.68  ?  466 SER E CB    1 
ATOM 6815 O OG    . SER D 2 95  ? 129.719 118.536 150.949 1.00 90.68  ?  466 SER E OG    1 
ATOM 6816 N N     . GLU D 2 96  ? 132.575 117.899 150.198 1.00 91.49  ?  467 GLU E N     1 
ATOM 6817 C CA    . GLU D 2 96  ? 133.899 117.987 150.806 1.00 91.49  ?  467 GLU E CA    1 
ATOM 6818 C C     . GLU D 2 96  ? 135.000 117.894 149.756 1.00 91.49  ?  467 GLU E C     1 
ATOM 6819 O O     . GLU D 2 96  ? 136.002 118.614 149.831 1.00 91.49  ?  467 GLU E O     1 
ATOM 6820 C CB    . GLU D 2 96  ? 134.065 116.889 151.855 1.00 91.49  ?  467 GLU E CB    1 
ATOM 6821 C CG    . GLU D 2 96  ? 133.044 116.949 152.977 1.00 91.49  ?  467 GLU E CG    1 
ATOM 6822 C CD    . GLU D 2 96  ? 133.236 115.847 153.999 1.00 91.49  ?  467 GLU E CD    1 
ATOM 6823 O OE1   . GLU D 2 96  ? 134.215 115.082 153.874 1.00 91.49  ?  467 GLU E OE1   1 
ATOM 6824 O OE2   . GLU D 2 96  ? 132.407 115.744 154.928 1.00 91.49  -1 467 GLU E OE2   1 
ATOM 6825 N N     . VAL D 2 97  ? 134.836 117.005 148.775 1.00 86.62  ?  468 VAL E N     1 
ATOM 6826 C CA    . VAL D 2 97  ? 135.861 116.836 147.751 1.00 86.62  ?  468 VAL E CA    1 
ATOM 6827 C C     . VAL D 2 97  ? 135.970 118.081 146.882 1.00 86.62  ?  468 VAL E C     1 
ATOM 6828 O O     . VAL D 2 97  ? 137.074 118.525 146.547 1.00 86.62  ?  468 VAL E O     1 
ATOM 6829 C CB    . VAL D 2 97  ? 135.569 115.586 146.904 1.00 86.62  ?  468 VAL E CB    1 
ATOM 6830 C CG1   . VAL D 2 97  ? 136.769 115.244 146.042 1.00 86.62  ?  468 VAL E CG1   1 
ATOM 6831 C CG2   . VAL D 2 97  ? 135.200 114.420 147.796 1.00 86.62  ?  468 VAL E CG2   1 
ATOM 6832 N N     . LEU D 2 98  ? 134.829 118.659 146.497 1.00 87.63  ?  469 LEU E N     1 
ATOM 6833 C CA    . LEU D 2 98  ? 134.845 119.785 145.569 1.00 87.63  ?  469 LEU E CA    1 
ATOM 6834 C C     . LEU D 2 98  ? 135.573 120.987 146.158 1.00 87.63  ?  469 LEU E C     1 
ATOM 6835 O O     . LEU D 2 98  ? 136.373 121.633 145.472 1.00 87.63  ?  469 LEU E O     1 
ATOM 6836 C CB    . LEU D 2 98  ? 133.416 120.158 145.177 1.00 87.63  ?  469 LEU E CB    1 
ATOM 6837 C CG    . LEU D 2 98  ? 132.640 119.066 144.442 1.00 87.63  ?  469 LEU E CG    1 
ATOM 6838 C CD1   . LEU D 2 98  ? 131.181 119.450 144.290 1.00 87.63  ?  469 LEU E CD1   1 
ATOM 6839 C CD2   . LEU D 2 98  ? 133.267 118.790 143.088 1.00 87.63  ?  469 LEU E CD2   1 
ATOM 6840 N N     . GLU D 2 99  ? 135.314 121.302 147.428 1.00 90.95  ?  470 GLU E N     1 
ATOM 6841 C CA    . GLU D 2 99  ? 136.012 122.421 148.050 1.00 90.95  ?  470 GLU E CA    1 
ATOM 6842 C C     . GLU D 2 99  ? 137.478 122.096 148.297 1.00 90.95  ?  470 GLU E C     1 
ATOM 6843 O O     . GLU D 2 99  ? 138.303 123.009 148.407 1.00 90.95  ?  470 GLU E O     1 
ATOM 6844 C CB    . GLU D 2 99  ? 135.323 122.815 149.356 1.00 90.95  ?  470 GLU E CB    1 
ATOM 6845 C CG    . GLU D 2 99  ? 135.115 121.668 150.327 1.00 90.95  ?  470 GLU E CG    1 
ATOM 6846 C CD    . GLU D 2 99  ? 136.285 121.480 151.270 1.00 90.95  ?  470 GLU E CD    1 
ATOM 6847 O OE1   . GLU D 2 99  ? 136.319 120.452 151.979 1.00 90.95  ?  470 GLU E OE1   1 
ATOM 6848 O OE2   . GLU D 2 99  ? 137.169 122.360 151.305 1.00 90.95  -1 470 GLU E OE2   1 
ATOM 6849 N N     . LEU D 2 100 ? 137.820 120.809 148.388 1.00 86.63  ?  471 LEU E N     1 
ATOM 6850 C CA    . LEU D 2 100 ? 139.215 120.429 148.584 1.00 86.63  ?  471 LEU E CA    1 
ATOM 6851 C C     . LEU D 2 100 ? 140.058 120.771 147.362 1.00 86.63  ?  471 LEU E C     1 
ATOM 6852 O O     . LEU D 2 100 ? 141.231 121.140 147.495 1.00 86.63  ?  471 LEU E O     1 
ATOM 6853 C CB    . LEU D 2 100 ? 139.313 118.938 148.904 1.00 86.63  ?  471 LEU E CB    1 
ATOM 6854 C CG    . LEU D 2 100 ? 140.725 118.390 149.119 1.00 86.63  ?  471 LEU E CG    1 
ATOM 6855 C CD1   . LEU D 2 100 ? 141.391 119.080 150.295 1.00 86.63  ?  471 LEU E CD1   1 
ATOM 6856 C CD2   . LEU D 2 100 ? 140.694 116.885 149.323 1.00 86.63  ?  471 LEU E CD2   1 
ATOM 6857 N N     . LEU D 2 101 ? 139.482 120.656 146.170 1.00 87.46  ?  472 LEU E N     1 
ATOM 6858 C CA    . LEU D 2 101 ? 140.221 120.930 144.947 1.00 87.46  ?  472 LEU E CA    1 
ATOM 6859 C C     . LEU D 2 101 ? 140.589 122.406 144.852 1.00 87.46  ?  472 LEU E C     1 
ATOM 6860 O O     . LEU D 2 101 ? 139.907 123.278 145.395 1.00 87.46  ?  472 LEU E O     1 
ATOM 6861 C CB    . LEU D 2 101 ? 139.402 120.523 143.725 1.00 87.46  ?  472 LEU E CB    1 
ATOM 6862 C CG    . LEU D 2 101 ? 139.149 119.027 143.552 1.00 87.46  ?  472 LEU E CG    1 
ATOM 6863 C CD1   . LEU D 2 101 ? 138.240 118.777 142.363 1.00 87.46  ?  472 LEU E CD1   1 
ATOM 6864 C CD2   . LEU D 2 101 ? 140.462 118.287 143.390 1.00 87.46  ?  472 LEU E CD2   1 
ATOM 6865 N N     . SER D 2 102 ? 141.686 122.677 144.152 1.00 87.75  ?  473 SER E N     1 
ATOM 6866 C CA    . SER D 2 102 ? 142.139 124.042 143.953 1.00 87.75  ?  473 SER E CA    1 
ATOM 6867 C C     . SER D 2 102 ? 141.288 124.737 142.894 1.00 87.75  ?  473 SER E C     1 
ATOM 6868 O O     . SER D 2 102 ? 140.486 124.117 142.191 1.00 87.75  ?  473 SER E O     1 
ATOM 6869 C CB    . SER D 2 102 ? 143.612 124.064 143.551 1.00 87.75  ?  473 SER E CB    1 
ATOM 6870 O OG    . SER D 2 102 ? 143.793 123.506 142.262 1.00 87.75  ?  473 SER E OG    1 
ATOM 6871 N N     . ALA D 2 103 ? 141.470 126.053 142.792 1.00 93.85  ?  474 ALA E N     1 
ATOM 6872 C CA    . ALA D 2 103 ? 140.717 126.834 141.812 1.00 93.85  ?  474 ALA E CA    1 
ATOM 6873 C C     . ALA D 2 103 ? 140.958 126.394 140.372 1.00 93.85  ?  474 ALA E C     1 
ATOM 6874 O O     . ALA D 2 103 ? 139.971 126.209 139.639 1.00 93.85  ?  474 ALA E O     1 
ATOM 6875 C CB    . ALA D 2 103 ? 141.028 128.323 141.997 1.00 93.85  ?  474 ALA E CB    1 
ATOM 6876 N N     . PRO D 2 104 ? 142.205 126.208 139.891 1.00 86.40  ?  475 PRO E N     1 
ATOM 6877 C CA    . PRO D 2 104 ? 142.375 125.822 138.483 1.00 86.40  ?  475 PRO E CA    1 
ATOM 6878 C C     . PRO D 2 104 ? 141.981 124.378 138.216 1.00 86.40  ?  475 PRO E C     1 
ATOM 6879 O O     . PRO D 2 104 ? 141.493 124.056 137.129 1.00 86.40  ?  475 PRO E O     1 
ATOM 6880 C CB    . PRO D 2 104 ? 143.868 126.054 138.227 1.00 86.40  ?  475 PRO E CB    1 
ATOM 6881 C CG    . PRO D 2 104 ? 144.508 125.920 139.547 1.00 86.40  ?  475 PRO E CG    1 
ATOM 6882 C CD    . PRO D 2 104 ? 143.501 126.305 140.590 1.00 86.40  ?  475 PRO E CD    1 
ATOM 6883 N N     . GLU D 2 105 ? 142.193 123.500 139.199 1.00 84.96  ?  476 GLU E N     1 
ATOM 6884 C CA    . GLU D 2 105 ? 141.812 122.102 139.030 1.00 84.96  ?  476 GLU E CA    1 
ATOM 6885 C C     . GLU D 2 105 ? 140.308 121.961 138.847 1.00 84.96  ?  476 GLU E C     1 
ATOM 6886 O O     . GLU D 2 105 ? 139.846 121.169 138.017 1.00 84.96  ?  476 GLU E O     1 
ATOM 6887 C CB    . GLU D 2 105 ? 142.287 121.277 140.225 1.00 84.96  ?  476 GLU E CB    1 
ATOM 6888 C CG    . GLU D 2 105 ? 143.772 120.961 140.209 1.00 84.96  ?  476 GLU E CG    1 
ATOM 6889 C CD    . GLU D 2 105 ? 144.276 120.465 141.549 1.00 84.96  ?  476 GLU E CD    1 
ATOM 6890 O OE1   . GLU D 2 105 ? 143.714 120.877 142.586 1.00 84.96  ?  476 GLU E OE1   1 
ATOM 6891 O OE2   . GLU D 2 105 ? 145.233 119.663 141.567 1.00 84.96  -1 476 GLU E OE2   1 
ATOM 6892 N N     . LEU D 2 106 ? 139.527 122.722 139.615 1.00 80.80  ?  477 LEU E N     1 
ATOM 6893 C CA    . LEU D 2 106 ? 138.077 122.678 139.469 1.00 80.80  ?  477 LEU E CA    1 
ATOM 6894 C C     . LEU D 2 106 ? 137.636 123.186 138.104 1.00 80.80  ?  477 LEU E C     1 
ATOM 6895 O O     . LEU D 2 106 ? 136.655 122.683 137.545 1.00 80.80  ?  477 LEU E O     1 
ATOM 6896 C CB    . LEU D 2 106 ? 137.414 123.492 140.577 1.00 80.80  ?  477 LEU E CB    1 
ATOM 6897 C CG    . LEU D 2 106 ? 136.020 123.030 140.993 1.00 80.80  ?  477 LEU E CG    1 
ATOM 6898 C CD1   . LEU D 2 106 ? 136.116 121.799 141.873 1.00 80.80  ?  477 LEU E CD1   1 
ATOM 6899 C CD2   . LEU D 2 106 ? 135.286 124.144 141.713 1.00 80.80  ?  477 LEU E CD2   1 
ATOM 6900 N N     . LYS D 2 107 ? 138.337 124.181 137.557 1.00 82.03  ?  478 LYS E N     1 
ATOM 6901 C CA    . LYS D 2 107 ? 137.995 124.684 136.231 1.00 82.03  ?  478 LYS E CA    1 
ATOM 6902 C C     . LYS D 2 107 ? 138.178 123.608 135.169 1.00 82.03  ?  478 LYS E C     1 
ATOM 6903 O O     . LYS D 2 107 ? 137.351 123.477 134.259 1.00 82.03  ?  478 LYS E O     1 
ATOM 6904 C CB    . LYS D 2 107 ? 138.840 125.914 135.903 1.00 82.03  ?  478 LYS E CB    1 
ATOM 6905 C CG    . LYS D 2 107 ? 138.463 126.597 134.601 1.00 82.03  ?  478 LYS E CG    1 
ATOM 6906 C CD    . LYS D 2 107 ? 139.222 127.901 134.424 1.00 82.03  ?  478 LYS E CD    1 
ATOM 6907 C CE    . LYS D 2 107 ? 140.009 127.908 133.123 1.00 82.03  ?  478 LYS E CE    1 
ATOM 6908 N NZ    . LYS D 2 107 ? 139.366 128.764 132.088 1.00 82.03  1  478 LYS E NZ    1 
ATOM 6909 N N     . SER D 2 108 ? 139.257 122.829 135.268 1.00 76.43  ?  479 SER E N     1 
ATOM 6910 C CA    . SER D 2 108 ? 139.485 121.754 134.307 1.00 76.43  ?  479 SER E CA    1 
ATOM 6911 C C     . SER D 2 108 ? 138.390 120.700 134.389 1.00 76.43  ?  479 SER E C     1 
ATOM 6912 O O     . SER D 2 108 ? 137.934 120.185 133.361 1.00 76.43  ?  479 SER E O     1 
ATOM 6913 C CB    . SER D 2 108 ? 140.856 121.122 134.542 1.00 76.43  ?  479 SER E CB    1 
ATOM 6914 O OG    . SER D 2 108 ? 141.164 121.084 135.924 1.00 76.43  ?  479 SER E OG    1 
ATOM 6915 N N     . LEU D 2 109 ? 137.960 120.359 135.605 1.00 68.12  ?  480 LEU E N     1 
ATOM 6916 C CA    . LEU D 2 109 ? 136.880 119.391 135.763 1.00 68.12  ?  480 LEU E CA    1 
ATOM 6917 C C     . LEU D 2 109 ? 135.581 119.913 135.164 1.00 68.12  ?  480 LEU E C     1 
ATOM 6918 O O     . LEU D 2 109 ? 134.804 119.147 134.583 1.00 68.12  ?  480 LEU E O     1 
ATOM 6919 C CB    . LEU D 2 109 ? 136.690 119.052 137.240 1.00 68.12  ?  480 LEU E CB    1 
ATOM 6920 C CG    . LEU D 2 109 ? 135.953 117.746 137.531 1.00 68.12  ?  480 LEU E CG    1 
ATOM 6921 C CD1   . LEU D 2 109 ? 136.841 116.559 137.211 1.00 68.12  ?  480 LEU E CD1   1 
ATOM 6922 C CD2   . LEU D 2 109 ? 135.496 117.700 138.978 1.00 68.12  ?  480 LEU E CD2   1 
ATOM 6923 N N     . ALA D 2 110 ? 135.326 121.216 135.303 1.00 69.14  ?  481 ALA E N     1 
ATOM 6924 C CA    . ALA D 2 110 ? 134.115 121.797 134.733 1.00 69.14  ?  481 ALA E CA    1 
ATOM 6925 C C     . ALA D 2 110 ? 134.108 121.682 133.215 1.00 69.14  ?  481 ALA E C     1 
ATOM 6926 O O     . ALA D 2 110 ? 133.059 121.437 132.608 1.00 69.14  ?  481 ALA E O     1 
ATOM 6927 C CB    . ALA D 2 110 ? 133.983 123.257 135.162 1.00 69.14  ?  481 ALA E CB    1 
ATOM 6928 N N     . LYS D 2 111 ? 135.269 121.866 132.584 1.00 66.21  ?  482 LYS E N     1 
ATOM 6929 C CA    . LYS D 2 111 ? 135.349 121.745 131.132 1.00 66.21  ?  482 LYS E CA    1 
ATOM 6930 C C     . LYS D 2 111 ? 135.004 120.335 130.675 1.00 66.21  ?  482 LYS E C     1 
ATOM 6931 O O     . LYS D 2 111 ? 134.320 120.152 129.661 1.00 66.21  ?  482 LYS E O     1 
ATOM 6932 C CB    . LYS D 2 111 ? 136.745 122.136 130.651 1.00 66.21  ?  482 LYS E CB    1 
ATOM 6933 C CG    . LYS D 2 111 ? 136.798 122.593 129.203 1.00 66.21  ?  482 LYS E CG    1 
ATOM 6934 C CD    . LYS D 2 111 ? 137.961 123.542 128.967 1.00 66.21  ?  482 LYS E CD    1 
ATOM 6935 C CE    . LYS D 2 111 ? 137.807 124.824 129.768 1.00 66.21  ?  482 LYS E CE    1 
ATOM 6936 N NZ    . LYS D 2 111 ? 136.403 125.319 129.766 1.00 66.21  1  482 LYS E NZ    1 
ATOM 6937 N N     . THR D 2 112 ? 135.474 119.323 131.408 1.00 60.93  ?  483 THR E N     1 
ATOM 6938 C CA    . THR D 2 112 ? 135.222 117.941 131.014 1.00 60.93  ?  483 THR E CA    1 
ATOM 6939 C C     . THR D 2 112 ? 133.735 117.612 131.048 1.00 60.93  ?  483 THR E C     1 
ATOM 6940 O O     . THR D 2 112 ? 133.223 116.929 130.154 1.00 60.93  ?  483 THR E O     1 
ATOM 6941 C CB    . THR D 2 112 ? 135.997 116.986 131.921 1.00 60.93  ?  483 THR E CB    1 
ATOM 6942 O OG1   . THR D 2 112 ? 137.348 117.443 132.054 1.00 60.93  ?  483 THR E OG1   1 
ATOM 6943 C CG2   . THR D 2 112 ? 135.998 115.586 131.335 1.00 60.93  ?  483 THR E CG2   1 
ATOM 6944 N N     . PHE D 2 113 ? 133.026 118.090 132.066 1.00 57.20  ?  484 PHE E N     1 
ATOM 6945 C CA    . PHE D 2 113 ? 131.617 117.773 132.245 1.00 57.20  ?  484 PHE E CA    1 
ATOM 6946 C C     . PHE D 2 113 ? 130.692 118.759 131.544 1.00 57.20  ?  484 PHE E C     1 
ATOM 6947 O O     . PHE D 2 113 ? 129.470 118.653 131.695 1.00 57.20  ?  484 PHE E O     1 
ATOM 6948 C CB    . PHE D 2 113 ? 131.282 117.706 133.735 1.00 57.20  ?  484 PHE E CB    1 
ATOM 6949 C CG    . PHE D 2 113 ? 131.789 116.467 134.412 1.00 57.20  ?  484 PHE E CG    1 
ATOM 6950 C CD1   . PHE D 2 113 ? 133.127 116.338 134.737 1.00 57.20  ?  484 PHE E CD1   1 
ATOM 6951 C CD2   . PHE D 2 113 ? 130.929 115.430 134.720 1.00 57.20  ?  484 PHE E CD2   1 
ATOM 6952 C CE1   . PHE D 2 113 ? 133.597 115.198 135.357 1.00 57.20  ?  484 PHE E CE1   1 
ATOM 6953 C CE2   . PHE D 2 113 ? 131.393 114.288 135.341 1.00 57.20  ?  484 PHE E CE2   1 
ATOM 6954 C CZ    . PHE D 2 113 ? 132.728 114.172 135.660 1.00 57.20  ?  484 PHE E CZ    1 
ATOM 6955 N N     . HIS D 2 114 ? 131.245 119.711 130.791 1.00 58.69  ?  485 HIS E N     1 
ATOM 6956 C CA    . HIS D 2 114 ? 130.466 120.676 130.014 1.00 58.69  ?  485 HIS E CA    1 
ATOM 6957 C C     . HIS D 2 114 ? 129.531 121.485 130.915 1.00 58.69  ?  485 HIS E C     1 
ATOM 6958 O O     . HIS D 2 114 ? 128.305 121.428 130.802 1.00 58.69  ?  485 HIS E O     1 
ATOM 6959 C CB    . HIS D 2 114 ? 129.684 119.976 128.897 1.00 58.69  ?  485 HIS E CB    1 
ATOM 6960 C CG    . HIS D 2 114 ? 130.513 119.045 128.070 1.00 58.69  ?  485 HIS E CG    1 
ATOM 6961 N ND1   . HIS D 2 114 ? 131.659 119.447 127.420 1.00 58.69  ?  485 HIS E ND1   1 
ATOM 6962 C CD2   . HIS D 2 114 ? 130.361 117.730 127.787 1.00 58.69  ?  485 HIS E CD2   1 
ATOM 6963 C CE1   . HIS D 2 114 ? 132.178 118.420 126.771 1.00 58.69  ?  485 HIS E CE1   1 
ATOM 6964 N NE2   . HIS D 2 114 ? 131.410 117.366 126.978 1.00 58.69  ?  485 HIS E NE2   1 
ATOM 6965 N N     . LEU D 2 115 ? 130.137 122.245 131.821 1.00 72.93  ?  486 LEU E N     1 
ATOM 6966 C CA    . LEU D 2 115 ? 129.368 123.086 132.723 1.00 72.93  ?  486 LEU E CA    1 
ATOM 6967 C C     . LEU D 2 115 ? 128.916 124.362 132.017 1.00 72.93  ?  486 LEU E C     1 
ATOM 6968 O O     . LEU D 2 115 ? 129.423 124.732 130.954 1.00 72.93  ?  486 LEU E O     1 
ATOM 6969 C CB    . LEU D 2 115 ? 130.184 123.431 133.968 1.00 72.93  ?  486 LEU E CB    1 
ATOM 6970 C CG    . LEU D 2 115 ? 129.893 122.572 135.200 1.00 72.93  ?  486 LEU E CG    1 
ATOM 6971 C CD1   . LEU D 2 115 ? 128.515 122.895 135.747 1.00 72.93  ?  486 LEU E CD1   1 
ATOM 6972 C CD2   . LEU D 2 115 ? 130.005 121.092 134.877 1.00 72.93  ?  486 LEU E CD2   1 
ATOM 6973 N N     . VAL D 2 116 ? 127.939 125.034 132.627 1.00 80.78  ?  487 VAL E N     1 
ATOM 6974 C CA    . VAL D 2 116 ? 127.344 126.215 132.009 1.00 80.78  ?  487 VAL E CA    1 
ATOM 6975 C C     . VAL D 2 116 ? 128.360 127.348 131.923 1.00 80.78  ?  487 VAL E C     1 
ATOM 6976 O O     . VAL D 2 116 ? 128.535 127.968 130.868 1.00 80.78  ?  487 VAL E O     1 
ATOM 6977 C CB    . VAL D 2 116 ? 126.086 126.648 132.782 1.00 80.78  ?  487 VAL E CB    1 
ATOM 6978 C CG1   . VAL D 2 116 ? 125.461 127.871 132.133 1.00 80.78  ?  487 VAL E CG1   1 
ATOM 6979 C CG2   . VAL D 2 116 ? 125.090 125.505 132.855 1.00 80.78  ?  487 VAL E CG2   1 
ATOM 6980 N N     . ASN D 2 117 ? 129.046 127.632 133.027 1.00 98.59  ?  488 ASN E N     1 
ATOM 6981 C CA    . ASN D 2 117 ? 130.018 128.722 133.100 1.00 98.59  ?  488 ASN E CA    1 
ATOM 6982 C C     . ASN D 2 117 ? 131.302 128.070 133.594 1.00 98.59  ?  488 ASN E C     1 
ATOM 6983 O O     . ASN D 2 117 ? 131.559 128.000 134.804 1.00 98.59  ?  488 ASN E O     1 
ATOM 6984 C CB    . ASN D 2 117 ? 129.507 129.852 134.005 1.00 98.59  ?  488 ASN E CB    1 
ATOM 6985 C CG    . ASN D 2 117 ? 130.617 130.743 134.576 1.00 98.59  ?  488 ASN E CG    1 
ATOM 6986 O OD1   . ASN D 2 117 ? 131.785 130.658 134.198 1.00 98.59  ?  488 ASN E OD1   1 
ATOM 6987 N ND2   . ASN D 2 117 ? 130.235 131.610 135.505 1.00 98.59  ?  488 ASN E ND2   1 
ATOM 6988 N N     . PRO D 2 118 ? 132.118 127.540 132.681 1.00 100.19 ?  489 PRO E N     1 
ATOM 6989 C CA    . PRO D 2 118 ? 133.368 126.890 133.105 1.00 100.19 ?  489 PRO E CA    1 
ATOM 6990 C C     . PRO D 2 118 ? 134.392 127.847 133.688 1.00 100.19 ?  489 PRO E C     1 
ATOM 6991 O O     . PRO D 2 118 ? 135.316 127.391 134.372 1.00 100.19 ?  489 PRO E O     1 
ATOM 6992 C CB    . PRO D 2 118 ? 133.883 126.241 131.814 1.00 100.19 ?  489 PRO E CB    1 
ATOM 6993 C CG    . PRO D 2 118 ? 133.237 127.008 130.712 1.00 100.19 ?  489 PRO E CG    1 
ATOM 6994 C CD    . PRO D 2 118 ? 131.905 127.457 131.227 1.00 100.19 ?  489 PRO E CD    1 
ATOM 6995 N N     . ASN D 2 119 ? 134.268 129.149 133.445 1.00 112.12 ?  490 ASN E N     1 
ATOM 6996 C CA    . ASN D 2 119 ? 135.256 130.130 133.881 1.00 112.12 ?  490 ASN E CA    1 
ATOM 6997 C C     . ASN D 2 119 ? 134.703 131.061 134.957 1.00 112.12 ?  490 ASN E C     1 
ATOM 6998 O O     . ASN D 2 119 ? 135.042 132.244 135.012 1.00 112.12 ?  490 ASN E O     1 
ATOM 6999 C CB    . ASN D 2 119 ? 135.772 130.939 132.694 1.00 112.12 ?  490 ASN E CB    1 
ATOM 7000 C CG    . ASN D 2 119 ? 134.667 131.351 131.745 1.00 112.12 ?  490 ASN E CG    1 
ATOM 7001 O OD1   . ASN D 2 119 ? 133.487 131.128 132.015 1.00 112.12 ?  490 ASN E OD1   1 
ATOM 7002 N ND2   . ASN D 2 119 ? 135.043 131.958 130.626 1.00 112.12 ?  490 ASN E ND2   1 
ATOM 7003 N N     . GLY D 2 120 ? 133.844 130.535 135.828 1.00 107.19 ?  491 GLY E N     1 
ATOM 7004 C CA    . GLY D 2 120 ? 133.325 131.287 136.949 1.00 107.19 ?  491 GLY E CA    1 
ATOM 7005 C C     . GLY D 2 120 ? 134.230 131.196 138.163 1.00 107.19 ?  491 GLY E C     1 
ATOM 7006 O O     . GLY D 2 120 ? 135.336 130.655 138.118 1.00 107.19 ?  491 GLY E O     1 
ATOM 7007 N N     . GLN D 2 121 ? 133.741 131.745 139.270 1.00 103.48 ?  492 GLN E N     1 
ATOM 7008 C CA    . GLN D 2 121 ? 134.477 131.662 140.520 1.00 103.48 ?  492 GLN E CA    1 
ATOM 7009 C C     . GLN D 2 121 ? 134.297 130.285 141.153 1.00 103.48 ?  492 GLN E C     1 
ATOM 7010 O O     . GLN D 2 121 ? 133.455 129.484 140.737 1.00 103.48 ?  492 GLN E O     1 
ATOM 7011 C CB    . GLN D 2 121 ? 134.025 132.754 141.488 1.00 103.48 ?  492 GLN E CB    1 
ATOM 7012 C CG    . GLN D 2 121 ? 134.321 134.164 141.004 1.00 103.48 ?  492 GLN E CG    1 
ATOM 7013 C CD    . GLN D 2 121 ? 133.678 135.224 141.875 1.00 103.48 ?  492 GLN E CD    1 
ATOM 7014 O OE1   . GLN D 2 121 ? 132.964 134.912 142.828 1.00 103.48 ?  492 GLN E OE1   1 
ATOM 7015 N NE2   . GLN D 2 121 ? 133.930 136.487 141.552 1.00 103.48 ?  492 GLN E NE2   1 
ATOM 7016 N N     . LYS D 2 122 ? 135.111 130.015 142.176 1.00 92.80  ?  493 LYS E N     1 
ATOM 7017 C CA    . LYS D 2 122 ? 135.100 128.698 142.803 1.00 92.80  ?  493 LYS E CA    1 
ATOM 7018 C C     . LYS D 2 122 ? 133.750 128.395 143.440 1.00 92.80  ?  493 LYS E C     1 
ATOM 7019 O O     . LYS D 2 122 ? 133.247 127.271 143.339 1.00 92.80  ?  493 LYS E O     1 
ATOM 7020 C CB    . LYS D 2 122 ? 136.215 128.603 143.843 1.00 92.80  ?  493 LYS E CB    1 
ATOM 7021 C CG    . LYS D 2 122 ? 136.227 127.297 144.619 1.00 92.80  ?  493 LYS E CG    1 
ATOM 7022 C CD    . LYS D 2 122 ? 137.326 127.290 145.666 1.00 92.80  ?  493 LYS E CD    1 
ATOM 7023 C CE    . LYS D 2 122 ? 137.244 126.055 146.545 1.00 92.80  ?  493 LYS E CE    1 
ATOM 7024 N NZ    . LYS D 2 122 ? 138.396 125.970 147.484 1.00 92.80  1  493 LYS E NZ    1 
ATOM 7025 N N     . GLN D 2 123 ? 133.149 129.385 144.103 1.00 86.26  ?  494 GLN E N     1 
ATOM 7026 C CA    . GLN D 2 123 ? 131.880 129.150 144.782 1.00 86.26  ?  494 GLN E CA    1 
ATOM 7027 C C     . GLN D 2 123 ? 130.772 128.804 143.793 1.00 86.26  ?  494 GLN E C     1 
ATOM 7028 O O     . GLN D 2 123 ? 130.010 127.859 144.028 1.00 86.26  ?  494 GLN E O     1 
ATOM 7029 C CB    . GLN D 2 123 ? 131.499 130.381 145.610 1.00 86.26  ?  494 GLN E CB    1 
ATOM 7030 C CG    . GLN D 2 123 ? 130.113 130.358 146.259 1.00 86.26  ?  494 GLN E CG    1 
ATOM 7031 C CD    . GLN D 2 123 ? 129.666 128.976 146.704 1.00 86.26  ?  494 GLN E CD    1 
ATOM 7032 O OE1   . GLN D 2 123 ? 130.400 128.259 147.386 1.00 86.26  ?  494 GLN E OE1   1 
ATOM 7033 N NE2   . GLN D 2 123 ? 128.456 128.593 146.313 1.00 86.26  ?  494 GLN E NE2   1 
ATOM 7034 N N     . GLN D 2 124 ? 130.675 129.536 142.681 1.00 86.09  ?  495 GLN E N     1 
ATOM 7035 C CA    . GLN D 2 124 ? 129.610 129.270 141.719 1.00 86.09  ?  495 GLN E CA    1 
ATOM 7036 C C     . GLN D 2 124 ? 129.767 127.898 141.077 1.00 86.09  ?  495 GLN E C     1 
ATOM 7037 O O     . GLN D 2 124 ? 128.772 127.236 140.759 1.00 86.09  ?  495 GLN E O     1 
ATOM 7038 C CB    . GLN D 2 124 ? 129.573 130.362 140.651 1.00 86.09  ?  495 GLN E CB    1 
ATOM 7039 C CG    . GLN D 2 124 ? 129.711 131.771 141.196 1.00 86.09  ?  495 GLN E CG    1 
ATOM 7040 C CD    . GLN D 2 124 ? 130.454 132.693 140.253 1.00 86.09  ?  495 GLN E CD    1 
ATOM 7041 O OE1   . GLN D 2 124 ? 130.498 132.461 139.045 1.00 86.09  ?  495 GLN E OE1   1 
ATOM 7042 N NE2   . GLN D 2 124 ? 131.025 133.759 140.798 1.00 86.09  ?  495 GLN E NE2   1 
ATOM 7043 N N     . LEU D 2 125 ? 131.007 127.454 140.871 1.00 81.51  ?  496 LEU E N     1 
ATOM 7044 C CA    . LEU D 2 125 ? 131.221 126.138 140.280 1.00 81.51  ?  496 LEU E CA    1 
ATOM 7045 C C     . LEU D 2 125 ? 130.802 125.019 141.224 1.00 81.51  ?  496 LEU E C     1 
ATOM 7046 O O     . LEU D 2 125 ? 130.282 123.993 140.771 1.00 81.51  ?  496 LEU E O     1 
ATOM 7047 C CB    . LEU D 2 125 ? 132.684 125.972 139.878 1.00 81.51  ?  496 LEU E CB    1 
ATOM 7048 C CG    . LEU D 2 125 ? 133.119 126.740 138.631 1.00 81.51  ?  496 LEU E CG    1 
ATOM 7049 C CD1   . LEU D 2 125 ? 134.630 126.717 138.489 1.00 81.51  ?  496 LEU E CD1   1 
ATOM 7050 C CD2   . LEU D 2 125 ? 132.451 126.163 137.397 1.00 81.51  ?  496 LEU E CD2   1 
ATOM 7051 N N     . VAL D 2 126 ? 131.020 125.193 142.529 1.00 77.68  ?  497 VAL E N     1 
ATOM 7052 C CA    . VAL D 2 126 ? 130.728 124.125 143.483 1.00 77.68  ?  497 VAL E CA    1 
ATOM 7053 C C     . VAL D 2 126 ? 129.234 123.831 143.518 1.00 77.68  ?  497 VAL E C     1 
ATOM 7054 O O     . VAL D 2 126 ? 128.811 122.671 143.461 1.00 77.68  ?  497 VAL E O     1 
ATOM 7055 C CB    . VAL D 2 126 ? 131.263 124.492 144.878 1.00 77.68  ?  497 VAL E CB    1 
ATOM 7056 C CG1   . VAL D 2 126 ? 130.633 123.602 145.936 1.00 77.68  ?  497 VAL E CG1   1 
ATOM 7057 C CG2   . VAL D 2 126 ? 132.776 124.374 144.907 1.00 77.68  ?  497 VAL E CG2   1 
ATOM 7058 N N     . ASP D 2 127 ? 128.411 124.877 143.612 1.00 78.91  ?  498 ASP E N     1 
ATOM 7059 C CA    . ASP D 2 127 ? 126.967 124.664 143.642 1.00 78.91  ?  498 ASP E CA    1 
ATOM 7060 C C     . ASP D 2 127 ? 126.469 124.094 142.321 1.00 78.91  ?  498 ASP E C     1 
ATOM 7061 O O     . ASP D 2 127 ? 125.562 123.254 142.305 1.00 78.91  ?  498 ASP E O     1 
ATOM 7062 C CB    . ASP D 2 127 ? 126.242 125.967 143.982 1.00 78.91  ?  498 ASP E CB    1 
ATOM 7063 C CG    . ASP D 2 127 ? 126.597 127.098 143.041 1.00 78.91  ?  498 ASP E CG    1 
ATOM 7064 O OD1   . ASP D 2 127 ? 126.221 127.030 141.852 1.00 78.91  ?  498 ASP E OD1   1 
ATOM 7065 O OD2   . ASP D 2 127 ? 127.245 128.064 143.495 1.00 78.91  -1 498 ASP E OD2   1 
ATOM 7066 N N     . ALA D 2 128 ? 127.045 124.541 141.203 1.00 72.22  ?  499 ALA E N     1 
ATOM 7067 C CA    . ALA D 2 128 ? 126.680 123.973 139.910 1.00 72.22  ?  499 ALA E CA    1 
ATOM 7068 C C     . ALA D 2 128 ? 127.041 122.495 139.840 1.00 72.22  ?  499 ALA E C     1 
ATOM 7069 O O     . ALA D 2 128 ? 126.255 121.679 139.344 1.00 72.22  ?  499 ALA E O     1 
ATOM 7070 C CB    . ALA D 2 128 ? 127.363 124.748 138.785 1.00 72.22  ?  499 ALA E CB    1 
ATOM 7071 N N     . PHE D 2 129 ? 128.228 122.132 140.331 1.00 68.98  ?  500 PHE E N     1 
ATOM 7072 C CA    . PHE D 2 129 ? 128.616 120.726 140.361 1.00 68.98  ?  500 PHE E CA    1 
ATOM 7073 C C     . PHE D 2 129 ? 127.695 119.920 141.265 1.00 68.98  ?  500 PHE E C     1 
ATOM 7074 O O     . PHE D 2 129 ? 127.260 118.821 140.901 1.00 68.98  ?  500 PHE E O     1 
ATOM 7075 C CB    . PHE D 2 129 ? 130.065 120.592 140.825 1.00 68.98  ?  500 PHE E CB    1 
ATOM 7076 C CG    . PHE D 2 129 ? 131.043 120.413 139.706 1.00 68.98  ?  500 PHE E CG    1 
ATOM 7077 C CD1   . PHE D 2 129 ? 131.094 119.227 139.000 1.00 68.98  ?  500 PHE E CD1   1 
ATOM 7078 C CD2   . PHE D 2 129 ? 131.913 121.430 139.362 1.00 68.98  ?  500 PHE E CD2   1 
ATOM 7079 C CE1   . PHE D 2 129 ? 131.995 119.059 137.970 1.00 68.98  ?  500 PHE E CE1   1 
ATOM 7080 C CE2   . PHE D 2 129 ? 132.815 121.268 138.333 1.00 68.98  ?  500 PHE E CE2   1 
ATOM 7081 C CZ    . PHE D 2 129 ? 132.857 120.081 137.636 1.00 68.98  ?  500 PHE E CZ    1 
ATOM 7082 N N     . LEU D 2 130 ? 127.387 120.450 142.450 1.00 73.21  ?  501 LEU E N     1 
ATOM 7083 C CA    . LEU D 2 130 ? 126.480 119.756 143.356 1.00 73.21  ?  501 LEU E CA    1 
ATOM 7084 C C     . LEU D 2 130 ? 125.090 119.636 142.746 1.00 73.21  ?  501 LEU E C     1 
ATOM 7085 O O     . LEU D 2 130 ? 124.428 118.602 142.887 1.00 73.21  ?  501 LEU E O     1 
ATOM 7086 C CB    . LEU D 2 130 ? 126.423 120.486 144.697 1.00 73.21  ?  501 LEU E CB    1 
ATOM 7087 C CG    . LEU D 2 130 ? 125.693 119.814 145.862 1.00 73.21  ?  501 LEU E CG    1 
ATOM 7088 C CD1   . LEU D 2 130 ? 125.797 118.298 145.787 1.00 73.21  ?  501 LEU E CD1   1 
ATOM 7089 C CD2   . LEU D 2 130 ? 126.242 120.323 147.185 1.00 73.21  ?  501 LEU E CD2   1 
ATOM 7090 N N     . LYS D 2 131 ? 124.631 120.687 142.063 1.00 75.84  ?  502 LYS E N     1 
ATOM 7091 C CA    . LYS D 2 131 ? 123.351 120.613 141.369 1.00 75.84  ?  502 LYS E CA    1 
ATOM 7092 C C     . LYS D 2 131 ? 123.391 119.574 140.256 1.00 75.84  ?  502 LYS E C     1 
ATOM 7093 O O     . LYS D 2 131 ? 122.403 118.870 140.019 1.00 75.84  ?  502 LYS E O     1 
ATOM 7094 C CB    . LYS D 2 131 ? 122.977 121.986 140.811 1.00 75.84  ?  502 LYS E CB    1 
ATOM 7095 C CG    . LYS D 2 131 ? 121.623 122.038 140.118 1.00 75.84  ?  502 LYS E CG    1 
ATOM 7096 C CD    . LYS D 2 131 ? 120.535 121.375 140.950 1.00 75.84  ?  502 LYS E CD    1 
ATOM 7097 C CE    . LYS D 2 131 ? 120.188 122.199 142.180 1.00 75.84  ?  502 LYS E CE    1 
ATOM 7098 N NZ    . LYS D 2 131 ? 119.384 121.415 143.159 1.00 75.84  1  502 LYS E NZ    1 
ATOM 7099 N N     . LEU D 2 132 ? 124.527 119.463 139.563 1.00 72.62  ?  503 LEU E N     1 
ATOM 7100 C CA    . LEU D 2 132 ? 124.635 118.516 138.458 1.00 72.62  ?  503 LEU E CA    1 
ATOM 7101 C C     . LEU D 2 132 ? 124.456 117.078 138.925 1.00 72.62  ?  503 LEU E C     1 
ATOM 7102 O O     . LEU D 2 132 ? 123.948 116.240 138.172 1.00 72.62  ?  503 LEU E O     1 
ATOM 7103 C CB    . LEU D 2 132 ? 125.983 118.684 137.758 1.00 72.62  ?  503 LEU E CB    1 
ATOM 7104 C CG    . LEU D 2 132 ? 126.276 117.755 136.579 1.00 72.62  ?  503 LEU E CG    1 
ATOM 7105 C CD1   . LEU D 2 132 ? 125.227 117.919 135.494 1.00 72.62  ?  503 LEU E CD1   1 
ATOM 7106 C CD2   . LEU D 2 132 ? 127.667 118.017 136.028 1.00 72.62  ?  503 LEU E CD2   1 
ATOM 7107 N N     . ALA D 2 133 ? 124.853 116.774 140.162 1.00 70.55  ?  504 ALA E N     1 
ATOM 7108 C CA    . ALA D 2 133 ? 124.737 115.412 140.667 1.00 70.55  ?  504 ALA E CA    1 
ATOM 7109 C C     . ALA D 2 133 ? 123.289 114.975 140.849 1.00 70.55  ?  504 ALA E C     1 
ATOM 7110 O O     . ALA D 2 133 ? 123.036 113.780 141.029 1.00 70.55  ?  504 ALA E O     1 
ATOM 7111 C CB    . ALA D 2 133 ? 125.488 115.276 141.991 1.00 70.55  ?  504 ALA E CB    1 
ATOM 7112 N N     . LYS D 2 134 ? 122.340 115.907 140.821 1.00 75.08  ?  505 LYS E N     1 
ATOM 7113 C CA    . LYS D 2 134 ? 120.930 115.577 140.972 1.00 75.08  ?  505 LYS E CA    1 
ATOM 7114 C C     . LYS D 2 134 ? 120.224 115.335 139.646 1.00 75.08  ?  505 LYS E C     1 
ATOM 7115 O O     . LYS D 2 134 ? 119.072 114.890 139.648 1.00 75.08  ?  505 LYS E O     1 
ATOM 7116 C CB    . LYS D 2 134 ? 120.208 116.690 141.737 1.00 75.08  ?  505 LYS E CB    1 
ATOM 7117 C CG    . LYS D 2 134 ? 120.577 116.768 143.205 1.00 75.08  ?  505 LYS E CG    1 
ATOM 7118 C CD    . LYS D 2 134 ? 119.853 117.911 143.893 1.00 75.08  ?  505 LYS E CD    1 
ATOM 7119 C CE    . LYS D 2 134 ? 120.579 118.336 145.156 1.00 75.08  ?  505 LYS E CE    1 
ATOM 7120 N NZ    . LYS D 2 134 ? 122.030 118.005 145.095 1.00 75.08  1  505 LYS E NZ    1 
ATOM 7121 N N     . GLN D 2 135 ? 120.876 115.614 138.521 1.00 78.33  ?  506 GLN E N     1 
ATOM 7122 C CA    . GLN D 2 135 ? 120.255 115.376 137.229 1.00 78.33  ?  506 GLN E CA    1 
ATOM 7123 C C     . GLN D 2 135 ? 120.132 113.882 136.951 1.00 78.33  ?  506 GLN E C     1 
ATOM 7124 O O     . GLN D 2 135 ? 120.853 113.051 137.510 1.00 78.33  ?  506 GLN E O     1 
ATOM 7125 C CB    . GLN D 2 135 ? 121.043 116.054 136.105 1.00 78.33  ?  506 GLN E CB    1 
ATOM 7126 C CG    . GLN D 2 135 ? 121.511 117.511 136.318 1.00 78.33  ?  506 GLN E CG    1 
ATOM 7127 C CD    . GLN D 2 135 ? 120.694 118.342 137.311 1.00 78.33  ?  506 GLN E CD    1 
ATOM 7128 O OE1   . GLN D 2 135 ? 119.483 118.172 137.460 1.00 78.33  ?  506 GLN E OE1   1 
ATOM 7129 N NE2   . GLN D 2 135 ? 121.368 119.266 137.982 1.00 78.33  ?  506 GLN E NE2   1 
ATOM 7130 N N     . ARG D 2 136 ? 119.194 113.548 136.073 1.00 64.81  ?  507 ARG E N     1 
ATOM 7131 C CA    . ARG D 2 136 ? 118.962 112.169 135.686 1.00 64.81  ?  507 ARG E CA    1 
ATOM 7132 C C     . ARG D 2 136 ? 120.061 111.703 134.737 1.00 64.81  ?  507 ARG E C     1 
ATOM 7133 O O     . ARG D 2 136 ? 120.933 112.471 134.322 1.00 64.81  ?  507 ARG E O     1 
ATOM 7134 C CB    . ARG D 2 136 ? 117.584 112.029 135.047 1.00 64.81  ?  507 ARG E CB    1 
ATOM 7135 C CG    . ARG D 2 136 ? 116.916 110.690 135.279 1.00 64.81  ?  507 ARG E CG    1 
ATOM 7136 C CD    . ARG D 2 136 ? 115.864 110.437 134.220 1.00 64.81  ?  507 ARG E CD    1 
ATOM 7137 N NE    . ARG D 2 136 ? 114.653 111.202 134.481 1.00 64.81  ?  507 ARG E NE    1 
ATOM 7138 C CZ    . ARG D 2 136 ? 113.442 110.848 134.078 1.00 64.81  ?  507 ARG E CZ    1 
ATOM 7139 N NH1   . ARG D 2 136 ? 113.243 109.744 133.376 1.00 64.81  1  507 ARG E NH1   1 
ATOM 7140 N NH2   . ARG D 2 136 ? 112.404 111.621 134.384 1.00 64.81  ?  507 ARG E NH2   1 
ATOM 7141 N N     . SER D 2 137 ? 120.026 110.420 134.392 1.00 63.38  ?  508 SER E N     1 
ATOM 7142 C CA    . SER D 2 137 ? 120.962 109.834 133.447 1.00 63.38  ?  508 SER E CA    1 
ATOM 7143 C C     . SER D 2 137 ? 120.174 109.165 132.329 1.00 63.38  ?  508 SER E C     1 
ATOM 7144 O O     . SER D 2 137 ? 118.942 109.214 132.288 1.00 63.38  ?  508 SER E O     1 
ATOM 7145 C CB    . SER D 2 137 ? 121.899 108.834 134.135 1.00 63.38  ?  508 SER E CB    1 
ATOM 7146 O OG    . SER D 2 137 ? 121.353 107.528 134.116 1.00 63.38  ?  508 SER E OG    1 
ATOM 7147 N N     . VAL D 2 138 ? 120.901 108.530 131.416 1.00 66.16  ?  509 VAL E N     1 
ATOM 7148 C CA    . VAL D 2 138 ? 120.296 107.855 130.275 1.00 66.16  ?  509 VAL E CA    1 
ATOM 7149 C C     . VAL D 2 138 ? 120.711 106.390 130.333 1.00 66.16  ?  509 VAL E C     1 
ATOM 7150 O O     . VAL D 2 138 ? 121.377 105.967 131.285 1.00 66.16  ?  509 VAL E O     1 
ATOM 7151 C CB    . VAL D 2 138 ? 120.697 108.537 128.949 1.00 66.16  ?  509 VAL E CB    1 
ATOM 7152 C CG1   . VAL D 2 138 ? 122.054 108.066 128.464 1.00 66.16  ?  509 VAL E CG1   1 
ATOM 7153 C CG2   . VAL D 2 138 ? 119.634 108.325 127.883 1.00 66.16  ?  509 VAL E CG2   1 
ATOM 7154 N N     . CYS D 2 139 ? 120.315 105.603 129.331 1.00 87.08  ?  510 CYS E N     1 
ATOM 7155 C CA    . CYS D 2 139 ? 120.606 104.173 129.281 1.00 87.08  ?  510 CYS E CA    1 
ATOM 7156 C C     . CYS D 2 139 ? 122.099 103.878 129.391 1.00 87.08  ?  510 CYS E C     1 
ATOM 7157 O O     . CYS D 2 139 ? 122.501 102.712 129.460 1.00 87.08  ?  510 CYS E O     1 
ATOM 7158 C CB    . CYS D 2 139 ? 120.054 103.567 127.988 1.00 87.08  ?  510 CYS E CB    1 
ATOM 7159 S SG    . CYS D 2 139 ? 118.252 103.462 127.914 1.00 87.08  ?  510 CYS E SG    1 
ATOM 7160 N N     . THR D 2 140 ? 122.926 104.929 129.387 1.00 71.32  ?  511 THR E N     1 
ATOM 7161 C CA    . THR D 2 140 ? 124.365 104.768 129.554 1.00 71.32  ?  511 THR E CA    1 
ATOM 7162 C C     . THR D 2 140 ? 124.705 103.974 130.805 1.00 71.32  ?  511 THR E C     1 
ATOM 7163 O O     . THR D 2 140 ? 125.674 103.206 130.815 1.00 71.32  ?  511 THR E O     1 
ATOM 7164 C CB    . THR D 2 140 ? 125.038 106.136 129.618 1.00 71.32  ?  511 THR E CB    1 
ATOM 7165 O OG1   . THR D 2 140 ? 126.439 105.961 129.849 1.00 71.32  ?  511 THR E OG1   1 
ATOM 7166 C CG2   . THR D 2 140 ? 124.456 106.987 130.738 1.00 71.32  ?  511 THR E CG2   1 
ATOM 7167 N N     . TRP D 2 141 ? 123.927 104.152 131.869 1.00 89.11  ?  512 TRP E N     1 
ATOM 7168 C CA    . TRP D 2 141 ? 124.076 103.392 133.099 1.00 89.11  ?  512 TRP E CA    1 
ATOM 7169 C C     . TRP D 2 141 ? 122.791 102.657 133.447 1.00 89.11  ?  512 TRP E C     1 
ATOM 7170 O O     . TRP D 2 141 ? 122.597 102.275 134.607 1.00 89.11  ?  512 TRP E O     1 
ATOM 7171 C CB    . TRP D 2 141 ? 124.485 104.323 134.244 1.00 89.11  ?  512 TRP E CB    1 
ATOM 7172 C CG    . TRP D 2 141 ? 125.412 103.703 135.236 1.00 89.11  ?  512 TRP E CG    1 
ATOM 7173 C CD1   . TRP D 2 141 ? 126.012 102.481 135.148 1.00 89.11  ?  512 TRP E CD1   1 
ATOM 7174 C CD2   . TRP D 2 141 ? 125.852 104.279 136.471 1.00 89.11  ?  512 TRP E CD2   1 
ATOM 7175 N NE1   . TRP D 2 141 ? 126.798 102.260 136.253 1.00 89.11  ?  512 TRP E NE1   1 
ATOM 7176 C CE2   . TRP D 2 141 ? 126.716 103.349 137.081 1.00 89.11  ?  512 TRP E CE2   1 
ATOM 7177 C CE3   . TRP D 2 141 ? 125.597 105.490 137.120 1.00 89.11  ?  512 TRP E CE3   1 
ATOM 7178 C CZ2   . TRP D 2 141 ? 127.327 103.593 138.308 1.00 89.11  ?  512 TRP E CZ2   1 
ATOM 7179 C CZ3   . TRP D 2 141 ? 126.204 105.730 138.338 1.00 89.11  ?  512 TRP E CZ3   1 
ATOM 7180 C CH2   . TRP D 2 141 ? 127.058 104.787 138.920 1.00 89.11  ?  512 TRP E CH2   1 
ATOM 7181 N N     . GLY D 2 142 ? 121.910 102.450 132.468 1.00 95.64  ?  513 GLY E N     1 
ATOM 7182 C CA    . GLY D 2 142 ? 120.575 101.983 132.754 1.00 95.64  ?  513 GLY E CA    1 
ATOM 7183 C C     . GLY D 2 142 ? 119.800 103.086 133.455 1.00 95.64  ?  513 GLY E C     1 
ATOM 7184 O O     . GLY D 2 142 ? 120.142 104.271 133.390 1.00 95.64  ?  513 GLY E O     1 
ATOM 7185 N N     . LYS D 2 143 ? 118.733 102.680 134.136 1.00 104.21 ?  514 LYS E N     1 
ATOM 7186 C CA    . LYS D 2 143 ? 118.014 103.606 135.005 1.00 104.21 ?  514 LYS E CA    1 
ATOM 7187 C C     . LYS D 2 143 ? 117.340 102.822 136.118 1.00 104.21 ?  514 LYS E C     1 
ATOM 7188 O O     . LYS D 2 143 ? 116.244 102.285 135.928 1.00 104.21 ?  514 LYS E O     1 
ATOM 7189 C CB    . LYS D 2 143 ? 116.993 104.431 134.219 1.00 104.21 ?  514 LYS E CB    1 
ATOM 7190 C CG    . LYS D 2 143 ? 116.369 103.720 133.035 1.00 104.21 ?  514 LYS E CG    1 
ATOM 7191 C CD    . LYS D 2 143 ? 116.119 104.703 131.906 1.00 104.21 ?  514 LYS E CD    1 
ATOM 7192 C CE    . LYS D 2 143 ? 115.900 103.991 130.588 1.00 104.21 ?  514 LYS E CE    1 
ATOM 7193 N NZ    . LYS D 2 143 ? 115.460 104.940 129.532 1.00 104.21 1  514 LYS E NZ    1 
ATOM 7194 N N     . ASN D 2 144 ? 118.001 102.756 137.271 1.00 114.52 ?  515 ASN E N     1 
ATOM 7195 C CA    . ASN D 2 144 ? 117.413 102.290 138.518 1.00 114.52 ?  515 ASN E CA    1 
ATOM 7196 C C     . ASN D 2 144 ? 117.402 103.391 139.563 1.00 114.52 ?  515 ASN E C     1 
ATOM 7197 O O     . ASN D 2 144 ? 116.404 103.569 140.272 1.00 114.52 ?  515 ASN E O     1 
ATOM 7198 C CB    . ASN D 2 144 ? 118.179 101.064 139.043 1.00 114.52 ?  515 ASN E CB    1 
ATOM 7199 C CG    . ASN D 2 144 ? 119.685 101.247 138.980 1.00 114.52 ?  515 ASN E CG    1 
ATOM 7200 O OD1   . ASN D 2 144 ? 120.228 102.216 139.512 1.00 114.52 ?  515 ASN E OD1   1 
ATOM 7201 N ND2   . ASN D 2 144 ? 120.368 100.314 138.328 1.00 114.52 ?  515 ASN E ND2   1 
ATOM 7202 N N     . LYS D 2 145 ? 118.496 104.136 139.670 1.00 112.32 ?  516 LYS E N     1 
ATOM 7203 C CA    . LYS D 2 145 ? 118.620 105.359 140.447 1.00 112.32 ?  516 LYS E CA    1 
ATOM 7204 C C     . LYS D 2 145 ? 119.804 106.120 139.865 1.00 112.32 ?  516 LYS E C     1 
ATOM 7205 O O     . LYS D 2 145 ? 120.889 105.541 139.724 1.00 112.32 ?  516 LYS E O     1 
ATOM 7206 C CB    . LYS D 2 145 ? 118.817 105.056 141.933 1.00 112.32 ?  516 LYS E CB    1 
ATOM 7207 C CG    . LYS D 2 145 ? 118.456 106.208 142.859 1.00 112.32 ?  516 LYS E CG    1 
ATOM 7208 C CD    . LYS D 2 145 ? 117.053 106.732 142.575 1.00 112.32 ?  516 LYS E CD    1 
ATOM 7209 C CE    . LYS D 2 145 ? 115.989 105.685 142.871 1.00 112.32 ?  516 LYS E CE    1 
ATOM 7210 N NZ    . LYS D 2 145 ? 114.705 105.995 142.183 1.00 112.32 1  516 LYS E NZ    1 
ATOM 7211 N N     . PRO D 2 146 ? 119.628 107.405 139.493 1.00 97.74  ?  517 PRO E N     1 
ATOM 7212 C CA    . PRO D 2 146 ? 120.654 108.116 138.711 1.00 97.74  ?  517 PRO E CA    1 
ATOM 7213 C C     . PRO D 2 146 ? 122.084 107.905 139.185 1.00 97.74  ?  517 PRO E C     1 
ATOM 7214 O O     . PRO D 2 146 ? 122.917 107.390 138.433 1.00 97.74  ?  517 PRO E O     1 
ATOM 7215 C CB    . PRO D 2 146 ? 120.242 109.585 138.863 1.00 97.74  ?  517 PRO E CB    1 
ATOM 7216 C CG    . PRO D 2 146 ? 118.765 109.547 139.076 1.00 97.74  ?  517 PRO E CG    1 
ATOM 7217 C CD    . PRO D 2 146 ? 118.393 108.194 139.635 1.00 97.74  ?  517 PRO E CD    1 
ATOM 7218 N N     . GLY D 2 147 ? 122.374 108.283 140.428 1.00 88.68  ?  518 GLY E N     1 
ATOM 7219 C CA    . GLY D 2 147 ? 123.688 108.066 141.002 1.00 88.68  ?  518 GLY E CA    1 
ATOM 7220 C C     . GLY D 2 147 ? 124.820 108.675 140.200 1.00 88.68  ?  518 GLY E C     1 
ATOM 7221 O O     . GLY D 2 147 ? 125.962 108.212 140.278 1.00 88.68  ?  518 GLY E O     1 
ATOM 7222 N N     . ILE D 2 148 ? 124.516 109.715 139.419 1.00 75.54  ?  519 ILE E N     1 
ATOM 7223 C CA    . ILE D 2 148 ? 125.535 110.342 138.584 1.00 75.54  ?  519 ILE E CA    1 
ATOM 7224 C C     . ILE D 2 148 ? 126.609 110.988 139.447 1.00 75.54  ?  519 ILE E C     1 
ATOM 7225 O O     . ILE D 2 148 ? 127.776 111.072 139.044 1.00 75.54  ?  519 ILE E O     1 
ATOM 7226 C CB    . ILE D 2 148 ? 124.881 111.352 137.619 1.00 75.54  ?  519 ILE E CB    1 
ATOM 7227 C CG1   . ILE D 2 148 ? 125.940 112.156 136.863 1.00 75.54  ?  519 ILE E CG1   1 
ATOM 7228 C CG2   . ILE D 2 148 ? 123.942 112.273 138.371 1.00 75.54  ?  519 ILE E CG2   1 
ATOM 7229 C CD1   . ILE D 2 148 ? 125.367 113.236 135.980 1.00 75.54  ?  519 ILE E CD1   1 
ATOM 7230 N N     . GLY D 2 149 ? 126.245 111.432 140.653 1.00 74.55  ?  520 GLY E N     1 
ATOM 7231 C CA    . GLY D 2 149 ? 127.231 112.001 141.554 1.00 74.55  ?  520 GLY E CA    1 
ATOM 7232 C C     . GLY D 2 149 ? 128.351 111.039 141.894 1.00 74.55  ?  520 GLY E C     1 
ATOM 7233 O O     . GLY D 2 149 ? 129.475 111.463 142.175 1.00 74.55  ?  520 GLY E O     1 
ATOM 7234 N N     . ALA D 2 150 ? 128.066 109.735 141.873 1.00 74.70  ?  521 ALA E N     1 
ATOM 7235 C CA    . ALA D 2 150 ? 129.120 108.748 142.079 1.00 74.70  ?  521 ALA E CA    1 
ATOM 7236 C C     . ALA D 2 150 ? 130.166 108.830 140.976 1.00 74.70  ?  521 ALA E C     1 
ATOM 7237 O O     . ALA D 2 150 ? 131.364 108.662 141.233 1.00 74.70  ?  521 ALA E O     1 
ATOM 7238 C CB    . ALA D 2 150 ? 128.522 107.344 142.151 1.00 74.70  ?  521 ALA E CB    1 
ATOM 7239 N N     . VAL D 2 151 ? 129.731 109.087 139.741 1.00 71.06  ?  522 VAL E N     1 
ATOM 7240 C CA    . VAL D 2 151 ? 130.670 109.248 138.635 1.00 71.06  ?  522 VAL E CA    1 
ATOM 7241 C C     . VAL D 2 151 ? 131.577 110.447 138.879 1.00 71.06  ?  522 VAL E C     1 
ATOM 7242 O O     . VAL D 2 151 ? 132.782 110.401 138.604 1.00 71.06  ?  522 VAL E O     1 
ATOM 7243 C CB    . VAL D 2 151 ? 129.911 109.378 137.302 1.00 71.06  ?  522 VAL E CB    1 
ATOM 7244 C CG1   . VAL D 2 151 ? 130.886 109.437 136.139 1.00 71.06  ?  522 VAL E CG1   1 
ATOM 7245 C CG2   . VAL D 2 151 ? 128.936 108.226 137.134 1.00 71.06  ?  522 VAL E CG2   1 
ATOM 7246 N N     . ILE D 2 152 ? 131.011 111.542 139.388 1.00 69.50  ?  523 ILE E N     1 
ATOM 7247 C CA    . ILE D 2 152 ? 131.820 112.713 139.700 1.00 69.50  ?  523 ILE E CA    1 
ATOM 7248 C C     . ILE D 2 152 ? 132.789 112.406 140.832 1.00 69.50  ?  523 ILE E C     1 
ATOM 7249 O O     . ILE D 2 152 ? 133.927 112.890 140.840 1.00 69.50  ?  523 ILE E O     1 
ATOM 7250 C CB    . ILE D 2 152 ? 130.917 113.911 140.043 1.00 69.50  ?  523 ILE E CB    1 
ATOM 7251 C CG1   . ILE D 2 152 ? 129.596 113.818 139.281 1.00 69.50  ?  523 ILE E CG1   1 
ATOM 7252 C CG2   . ILE D 2 152 ? 131.624 115.214 139.725 1.00 69.50  ?  523 ILE E CG2   1 
ATOM 7253 C CD1   . ILE D 2 152 ? 128.648 114.957 139.570 1.00 69.50  ?  523 ILE E CD1   1 
ATOM 7254 N N     . LEU D 2 153 ? 132.357 111.601 141.805 1.00 73.95  ?  524 LEU E N     1 
ATOM 7255 C CA    . LEU D 2 153 ? 133.174 111.360 142.990 1.00 73.95  ?  524 LEU E CA    1 
ATOM 7256 C C     . LEU D 2 153 ? 134.469 110.639 142.639 1.00 73.95  ?  524 LEU E C     1 
ATOM 7257 O O     . LEU D 2 153 ? 135.547 111.011 143.115 1.00 73.95  ?  524 LEU E O     1 
ATOM 7258 C CB    . LEU D 2 153 ? 132.376 110.564 144.020 1.00 73.95  ?  524 LEU E CB    1 
ATOM 7259 C CG    . LEU D 2 153 ? 133.097 110.308 145.343 1.00 73.95  ?  524 LEU E CG    1 
ATOM 7260 C CD1   . LEU D 2 153 ? 133.340 111.617 146.070 1.00 73.95  ?  524 LEU E CD1   1 
ATOM 7261 C CD2   . LEU D 2 153 ? 132.298 109.351 146.208 1.00 73.95  ?  524 LEU E CD2   1 
ATOM 7262 N N     . LYS D 2 154 ? 134.385 109.597 141.806 1.00 73.35  ?  525 LYS E N     1 
ATOM 7263 C CA    . LYS D 2 154 ? 135.590 108.855 141.446 1.00 73.35  ?  525 LYS E CA    1 
ATOM 7264 C C     . LYS D 2 154 ? 136.557 109.726 140.656 1.00 73.35  ?  525 LYS E C     1 
ATOM 7265 O O     . LYS D 2 154 ? 137.773 109.669 140.870 1.00 73.35  ?  525 LYS E O     1 
ATOM 7266 C CB    . LYS D 2 154 ? 135.226 107.598 140.656 1.00 73.35  ?  525 LYS E CB    1 
ATOM 7267 C CG    . LYS D 2 154 ? 134.006 107.744 139.770 1.00 73.35  ?  525 LYS E CG    1 
ATOM 7268 C CD    . LYS D 2 154 ? 133.953 106.652 138.715 1.00 73.35  ?  525 LYS E CD    1 
ATOM 7269 C CE    . LYS D 2 154 ? 134.795 107.013 137.503 1.00 73.35  ?  525 LYS E CE    1 
ATOM 7270 N NZ    . LYS D 2 154 ? 134.102 107.986 136.614 1.00 73.35  1  525 LYS E NZ    1 
ATOM 7271 N N     . ARG D 2 155 ? 136.036 110.535 139.732 1.00 73.12  ?  526 ARG E N     1 
ATOM 7272 C CA    . ARG D 2 155 ? 136.894 111.458 138.997 1.00 73.12  ?  526 ARG E CA    1 
ATOM 7273 C C     . ARG D 2 155 ? 137.493 112.509 139.921 1.00 73.12  ?  526 ARG E C     1 
ATOM 7274 O O     . ARG D 2 155 ? 138.676 112.848 139.801 1.00 73.12  ?  526 ARG E O     1 
ATOM 7275 C CB    . ARG D 2 155 ? 136.105 112.123 137.870 1.00 73.12  ?  526 ARG E CB    1 
ATOM 7276 C CG    . ARG D 2 155 ? 136.044 111.307 136.594 1.00 73.12  ?  526 ARG E CG    1 
ATOM 7277 C CD    . ARG D 2 155 ? 137.420 111.165 135.969 1.00 73.12  ?  526 ARG E CD    1 
ATOM 7278 N NE    . ARG D 2 155 ? 137.815 112.363 135.239 1.00 73.12  ?  526 ARG E NE    1 
ATOM 7279 C CZ    . ARG D 2 155 ? 137.394 112.672 134.020 1.00 73.12  ?  526 ARG E CZ    1 
ATOM 7280 N NH1   . ARG D 2 155 ? 136.560 111.888 133.357 1.00 73.12  1  526 ARG E NH1   1 
ATOM 7281 N NH2   . ARG D 2 155 ? 137.823 113.794 133.451 1.00 73.12  ?  526 ARG E NH2   1 
ATOM 7282 N N     . ALA D 2 156 ? 136.693 113.038 140.848 1.00 76.00  ?  527 ALA E N     1 
ATOM 7283 C CA    . ALA D 2 156 ? 137.186 114.078 141.744 1.00 76.00  ?  527 ALA E CA    1 
ATOM 7284 C C     . ALA D 2 156 ? 138.215 113.531 142.724 1.00 76.00  ?  527 ALA E C     1 
ATOM 7285 O O     . ALA D 2 156 ? 139.209 114.202 143.025 1.00 76.00  ?  527 ALA E O     1 
ATOM 7286 C CB    . ALA D 2 156 ? 136.020 114.721 142.494 1.00 76.00  ?  527 ALA E CB    1 
ATOM 7287 N N     . LYS D 2 157 ? 137.995 112.317 143.235 1.00 77.13  ?  528 LYS E N     1 
ATOM 7288 C CA    . LYS D 2 157 ? 138.932 111.740 144.195 1.00 77.13  ?  528 LYS E CA    1 
ATOM 7289 C C     . LYS D 2 157 ? 140.304 111.531 143.569 1.00 77.13  ?  528 LYS E C     1 
ATOM 7290 O O     . LYS D 2 157 ? 141.332 111.784 144.209 1.00 77.13  ?  528 LYS E O     1 
ATOM 7291 C CB    . LYS D 2 157 ? 138.383 110.423 144.740 1.00 77.13  ?  528 LYS E CB    1 
ATOM 7292 C CG    . LYS D 2 157 ? 137.345 110.595 145.833 1.00 77.13  ?  528 LYS E CG    1 
ATOM 7293 C CD    . LYS D 2 157 ? 136.863 109.253 146.354 1.00 77.13  ?  528 LYS E CD    1 
ATOM 7294 C CE    . LYS D 2 157 ? 137.913 108.594 147.231 1.00 77.13  ?  528 LYS E CE    1 
ATOM 7295 N NZ    . LYS D 2 157 ? 137.377 107.392 147.927 1.00 77.13  1  528 LYS E NZ    1 
ATOM 7296 N N     . ALA D 2 158 ? 140.341 111.065 142.319 1.00 76.67  ?  529 ALA E N     1 
ATOM 7297 C CA    . ALA D 2 158 ? 141.616 110.901 141.629 1.00 76.67  ?  529 ALA E CA    1 
ATOM 7298 C C     . ALA D 2 158 ? 142.315 112.241 141.441 1.00 76.67  ?  529 ALA E C     1 
ATOM 7299 O O     . ALA D 2 158 ? 143.537 112.341 141.594 1.00 76.67  ?  529 ALA E O     1 
ATOM 7300 C CB    . ALA D 2 158 ? 141.401 110.212 140.283 1.00 76.67  ?  529 ALA E CB    1 
ATOM 7301 N N     . LEU D 2 159 ? 141.554 113.283 141.100 1.00 77.86  ?  530 LEU E N     1 
ATOM 7302 C CA    . LEU D 2 159 ? 142.139 114.612 140.952 1.00 77.86  ?  530 LEU E CA    1 
ATOM 7303 C C     . LEU D 2 159 ? 142.684 115.127 142.278 1.00 77.86  ?  530 LEU E C     1 
ATOM 7304 O O     . LEU D 2 159 ? 143.760 115.735 142.322 1.00 77.86  ?  530 LEU E O     1 
ATOM 7305 C CB    . LEU D 2 159 ? 141.104 115.585 140.387 1.00 77.86  ?  530 LEU E CB    1 
ATOM 7306 C CG    . LEU D 2 159 ? 141.015 115.766 138.869 1.00 77.86  ?  530 LEU E CG    1 
ATOM 7307 C CD1   . LEU D 2 159 ? 142.145 116.655 138.378 1.00 77.86  ?  530 LEU E CD1   1 
ATOM 7308 C CD2   . LEU D 2 159 ? 141.024 114.433 138.138 1.00 77.86  ?  530 LEU E CD2   1 
ATOM 7309 N N     . ALA D 2 160 ? 141.952 114.898 143.371 1.00 86.39  ?  531 ALA E N     1 
ATOM 7310 C CA    . ALA D 2 160 ? 142.371 115.424 144.666 1.00 86.39  ?  531 ALA E CA    1 
ATOM 7311 C C     . ALA D 2 160 ? 143.634 114.738 145.170 1.00 86.39  ?  531 ALA E C     1 
ATOM 7312 O O     . ALA D 2 160 ? 144.569 115.405 145.627 1.00 86.39  ?  531 ALA E O     1 
ATOM 7313 C CB    . ALA D 2 160 ? 141.240 115.277 145.681 1.00 86.39  ?  531 ALA E CB    1 
ATOM 7314 N N     . GLY D 2 161 ? 143.684 113.412 145.094 1.00 94.06  ?  532 GLY E N     1 
ATOM 7315 C CA    . GLY D 2 161 ? 144.829 112.686 145.601 1.00 94.06  ?  532 GLY E CA    1 
ATOM 7316 C C     . GLY D 2 161 ? 144.701 112.369 147.081 1.00 94.06  ?  532 GLY E C     1 
ATOM 7317 O O     . GLY D 2 161 ? 143.621 112.432 147.678 1.00 94.06  ?  532 GLY E O     1 
ATOM 7318 N N     . GLN D 2 162 ? 145.837 112.019 147.677 1.00 99.78  ?  533 GLN E N     1 
ATOM 7319 C CA    . GLN D 2 162 ? 145.861 111.643 149.084 1.00 99.78  ?  533 GLN E CA    1 
ATOM 7320 C C     . GLN D 2 162 ? 145.557 112.849 149.965 1.00 99.78  ?  533 GLN E C     1 
ATOM 7321 O O     . GLN D 2 162 ? 146.039 113.957 149.719 1.00 99.78  ?  533 GLN E O     1 
ATOM 7322 C CB    . GLN D 2 162 ? 147.224 111.056 149.450 1.00 99.78  ?  533 GLN E CB    1 
ATOM 7323 C CG    . GLN D 2 162 ? 147.176 109.703 150.155 1.00 99.78  ?  533 GLN E CG    1 
ATOM 7324 C CD    . GLN D 2 162 ? 146.397 109.722 151.459 1.00 99.78  ?  533 GLN E CD    1 
ATOM 7325 O OE1   . GLN D 2 162 ? 146.199 110.772 152.069 1.00 99.78  ?  533 GLN E OE1   1 
ATOM 7326 N NE2   . GLN D 2 162 ? 145.950 108.549 151.893 1.00 99.78  ?  533 GLN E NE2   1 
ATOM 7327 N N     . SER D 2 163 ? 144.750 112.627 151.001 1.00 95.02  ?  534 SER E N     1 
ATOM 7328 C CA    . SER D 2 163 ? 144.403 113.683 151.939 1.00 95.02  ?  534 SER E CA    1 
ATOM 7329 C C     . SER D 2 163 ? 143.983 113.060 153.262 1.00 95.02  ?  534 SER E C     1 
ATOM 7330 O O     . SER D 2 163 ? 143.527 111.915 153.314 1.00 95.02  ?  534 SER E O     1 
ATOM 7331 C CB    . SER D 2 163 ? 143.289 114.581 151.392 1.00 95.02  ?  534 SER E CB    1 
ATOM 7332 O OG    . SER D 2 163 ? 143.716 115.269 150.230 1.00 95.02  ?  534 SER E OG    1 
ATOM 7333 N N     . VAL D 2 164 ? 144.144 113.833 154.338 1.00 90.76  ?  535 VAL E N     1 
ATOM 7334 C CA    . VAL D 2 164 ? 143.773 113.399 155.677 1.00 90.76  ?  535 VAL E CA    1 
ATOM 7335 C C     . VAL D 2 164 ? 143.044 114.532 156.385 1.00 90.76  ?  535 VAL E C     1 
ATOM 7336 O O     . VAL D 2 164 ? 143.150 115.703 156.014 1.00 90.76  ?  535 VAL E O     1 
ATOM 7337 C CB    . VAL D 2 164 ? 144.990 112.952 156.513 1.00 90.76  ?  535 VAL E CB    1 
ATOM 7338 C CG1   . VAL D 2 164 ? 145.561 111.652 155.971 1.00 90.76  ?  535 VAL E CG1   1 
ATOM 7339 C CG2   . VAL D 2 164 ? 146.044 114.044 156.536 1.00 90.76  ?  535 VAL E CG2   1 
ATOM 7340 N N     . ARG D 2 165 ? 142.297 114.163 157.423 1.00 88.60  ?  536 ARG E N     1 
ATOM 7341 C CA    . ARG D 2 165 ? 141.581 115.124 158.248 1.00 88.60  ?  536 ARG E CA    1 
ATOM 7342 C C     . ARG D 2 165 ? 141.593 114.627 159.684 1.00 88.60  ?  536 ARG E C     1 
ATOM 7343 O O     . ARG D 2 165 ? 141.516 113.420 159.928 1.00 88.60  ?  536 ARG E O     1 
ATOM 7344 C CB    . ARG D 2 165 ? 140.139 115.324 157.766 1.00 88.60  ?  536 ARG E CB    1 
ATOM 7345 C CG    . ARG D 2 165 ? 139.298 116.214 158.672 1.00 88.60  ?  536 ARG E CG    1 
ATOM 7346 C CD    . ARG D 2 165 ? 138.193 116.919 157.902 1.00 88.60  ?  536 ARG E CD    1 
ATOM 7347 N NE    . ARG D 2 165 ? 137.362 115.991 157.145 1.00 88.60  ?  536 ARG E NE    1 
ATOM 7348 C CZ    . ARG D 2 165 ? 136.555 115.086 157.683 1.00 88.60  ?  536 ARG E CZ    1 
ATOM 7349 N NH1   . ARG D 2 165 ? 136.404 114.983 158.993 1.00 88.60  1  536 ARG E NH1   1 
ATOM 7350 N NH2   . ARG D 2 165 ? 135.872 114.271 156.885 1.00 88.60  ?  536 ARG E NH2   1 
ATOM 7351 N N     . ILE D 2 166 ? 141.694 115.562 160.629 1.00 92.45  ?  537 ILE E N     1 
ATOM 7352 C CA    . ILE D 2 166 ? 141.694 115.205 162.041 1.00 92.45  ?  537 ILE E CA    1 
ATOM 7353 C C     . ILE D 2 166 ? 140.352 114.587 162.404 1.00 92.45  ?  537 ILE E C     1 
ATOM 7354 O O     . ILE D 2 166 ? 139.291 115.168 162.140 1.00 92.45  ?  537 ILE E O     1 
ATOM 7355 C CB    . ILE D 2 166 ? 141.987 116.439 162.905 1.00 92.45  ?  537 ILE E CB    1 
ATOM 7356 C CG1   . ILE D 2 166 ? 143.451 116.855 162.760 1.00 92.45  ?  537 ILE E CG1   1 
ATOM 7357 C CG2   . ILE D 2 166 ? 141.650 116.162 164.360 1.00 92.45  ?  537 ILE E CG2   1 
ATOM 7358 C CD1   . ILE D 2 166 ? 144.405 116.013 163.566 1.00 92.45  ?  537 ILE E CD1   1 
ATOM 7359 N N     . CYS D 2 167 ? 140.391 113.401 163.004 1.00 95.07  ?  538 CYS E N     1 
ATOM 7360 C CA    . CYS D 2 167 ? 139.164 112.731 163.411 1.00 95.07  ?  538 CYS E CA    1 
ATOM 7361 C C     . CYS D 2 167 ? 138.458 113.531 164.497 1.00 95.07  ?  538 CYS E C     1 
ATOM 7362 O O     . CYS D 2 167 ? 139.078 113.968 165.470 1.00 95.07  ?  538 CYS E O     1 
ATOM 7363 C CB    . CYS D 2 167 ? 139.466 111.318 163.907 1.00 95.07  ?  538 CYS E CB    1 
ATOM 7364 S SG    . CYS D 2 167 ? 139.934 110.154 162.610 1.00 95.07  ?  538 CYS E SG    1 
ATOM 7365 N N     . LYS D 2 168 ? 137.147 113.715 164.326 1.00 97.41  ?  539 LYS E N     1 
ATOM 7366 C CA    . LYS D 2 168 ? 136.384 114.539 165.257 1.00 97.41  ?  539 LYS E CA    1 
ATOM 7367 C C     . LYS D 2 168 ? 136.363 113.943 166.658 1.00 97.41  ?  539 LYS E C     1 
ATOM 7368 O O     . LYS D 2 168 ? 136.406 114.689 167.643 1.00 97.41  ?  539 LYS E O     1 
ATOM 7369 C CB    . LYS D 2 168 ? 134.957 114.730 164.746 1.00 97.41  ?  539 LYS E CB    1 
ATOM 7370 C CG    . LYS D 2 168 ? 134.868 115.449 163.413 1.00 97.41  ?  539 LYS E CG    1 
ATOM 7371 C CD    . LYS D 2 168 ? 133.423 115.603 162.968 1.00 97.41  ?  539 LYS E CD    1 
ATOM 7372 C CE    . LYS D 2 168 ? 133.324 116.425 161.694 1.00 97.41  ?  539 LYS E CE    1 
ATOM 7373 N NZ    . LYS D 2 168 ? 132.241 115.931 160.800 1.00 97.41  1  539 LYS E NZ    1 
ATOM 7374 N N     . GLY D 2 169 ? 136.282 112.618 166.766 1.00 99.21  ?  540 GLY E N     1 
ATOM 7375 C CA    . GLY D 2 169 ? 136.278 111.945 168.043 1.00 99.21  ?  540 GLY E CA    1 
ATOM 7376 C C     . GLY D 2 169 ? 137.425 112.382 168.930 1.00 99.21  ?  540 GLY E C     1 
ATOM 7377 O O     . GLY D 2 169 ? 137.224 112.967 169.999 1.00 99.21  ?  540 GLY E O     1 
ATOM 7378 N N     . PRO D 2 170 ? 138.658 112.101 168.504 1.00 102.31 ?  541 PRO E N     1 
ATOM 7379 C CA    . PRO D 2 170 ? 139.814 112.651 169.227 1.00 102.31 ?  541 PRO E CA    1 
ATOM 7380 C C     . PRO D 2 170 ? 139.826 114.167 169.276 1.00 102.31 ?  541 PRO E C     1 
ATOM 7381 O O     . PRO D 2 170 ? 140.259 114.738 170.283 1.00 102.31 ?  541 PRO E O     1 
ATOM 7382 C CB    . PRO D 2 170 ? 141.012 112.097 168.444 1.00 102.31 ?  541 PRO E CB    1 
ATOM 7383 C CG    . PRO D 2 170 ? 140.492 110.861 167.793 1.00 102.31 ?  541 PRO E CG    1 
ATOM 7384 C CD    . PRO D 2 170 ? 139.065 111.162 167.446 1.00 102.31 ?  541 PRO E CD    1 
ATOM 7385 N N     . ARG D 2 171 ? 139.363 114.841 168.220 1.00 103.16 ?  542 ARG E N     1 
ATOM 7386 C CA    . ARG D 2 171 ? 139.375 116.301 168.219 1.00 103.16 ?  542 ARG E CA    1 
ATOM 7387 C C     . ARG D 2 171 ? 138.415 116.859 169.263 1.00 103.16 ?  542 ARG E C     1 
ATOM 7388 O O     . ARG D 2 171 ? 138.800 117.711 170.073 1.00 103.16 ?  542 ARG E O     1 
ATOM 7389 C CB    . ARG D 2 171 ? 139.022 116.823 166.824 1.00 103.16 ?  542 ARG E CB    1 
ATOM 7390 C CG    . ARG D 2 171 ? 138.495 118.257 166.760 1.00 103.16 ?  542 ARG E CG    1 
ATOM 7391 C CD    . ARG D 2 171 ? 139.465 119.267 167.368 1.00 103.16 ?  542 ARG E CD    1 
ATOM 7392 N NE    . ARG D 2 171 ? 140.644 119.482 166.538 1.00 103.16 ?  542 ARG E NE    1 
ATOM 7393 C CZ    . ARG D 2 171 ? 140.644 120.147 165.391 1.00 103.16 ?  542 ARG E CZ    1 
ATOM 7394 N NH1   . ARG D 2 171 ? 139.540 120.691 164.906 1.00 103.16 1  542 ARG E NH1   1 
ATOM 7395 N NH2   . ARG D 2 171 ? 141.783 120.275 164.716 1.00 103.16 ?  542 ARG E NH2   1 
ATOM 7396 N N     . ALA D 2 172 ? 137.166 116.388 169.264 1.00 106.50 ?  543 ALA E N     1 
ATOM 7397 C CA    . ALA D 2 172 ? 136.178 116.918 170.198 1.00 106.50 ?  543 ALA E CA    1 
ATOM 7398 C C     . ALA D 2 172 ? 136.566 116.627 171.641 1.00 106.50 ?  543 ALA E C     1 
ATOM 7399 O O     . ALA D 2 172 ? 136.413 117.485 172.519 1.00 106.50 ?  543 ALA E O     1 
ATOM 7400 C CB    . ALA D 2 172 ? 134.797 116.341 169.888 1.00 106.50 ?  543 ALA E CB    1 
ATOM 7401 N N     . VAL D 2 173 ? 137.067 115.420 171.908 1.00 109.49 ?  544 VAL E N     1 
ATOM 7402 C CA    . VAL D 2 173 ? 137.444 115.065 173.273 1.00 109.49 ?  544 VAL E CA    1 
ATOM 7403 C C     . VAL D 2 173 ? 138.677 115.845 173.713 1.00 109.49 ?  544 VAL E C     1 
ATOM 7404 O O     . VAL D 2 173 ? 138.778 116.270 174.870 1.00 109.49 ?  544 VAL E O     1 
ATOM 7405 C CB    . VAL D 2 173 ? 137.641 113.541 173.403 1.00 109.49 ?  544 VAL E CB    1 
ATOM 7406 C CG1   . VAL D 2 173 ? 138.939 113.083 172.756 1.00 109.49 ?  544 VAL E CG1   1 
ATOM 7407 C CG2   . VAL D 2 173 ? 137.624 113.145 174.859 1.00 109.49 ?  544 VAL E CG2   1 
ATOM 7408 N N     . PHE D 2 174 ? 139.629 116.055 172.802 1.00 110.16 ?  545 PHE E N     1 
ATOM 7409 C CA    . PHE D 2 174 ? 140.852 116.753 173.176 1.00 110.16 ?  545 PHE E CA    1 
ATOM 7410 C C     . PHE D 2 174 ? 140.630 118.258 173.238 1.00 110.16 ?  545 PHE E C     1 
ATOM 7411 O O     . PHE D 2 174 ? 141.359 118.964 173.943 1.00 110.16 ?  545 PHE E O     1 
ATOM 7412 C CB    . PHE D 2 174 ? 141.975 116.392 172.202 1.00 110.16 ?  545 PHE E CB    1 
ATOM 7413 C CG    . PHE D 2 174 ? 143.353 116.565 172.770 1.00 110.16 ?  545 PHE E CG    1 
ATOM 7414 C CD1   . PHE D 2 174 ? 143.868 117.821 173.024 1.00 110.16 ?  545 PHE E CD1   1 
ATOM 7415 C CD2   . PHE D 2 174 ? 144.121 115.457 173.081 1.00 110.16 ?  545 PHE E CD2   1 
ATOM 7416 C CE1   . PHE D 2 174 ? 145.126 117.972 173.556 1.00 110.16 ?  545 PHE E CE1   1 
ATOM 7417 C CE2   . PHE D 2 174 ? 145.382 115.603 173.615 1.00 110.16 ?  545 PHE E CE2   1 
ATOM 7418 C CZ    . PHE D 2 174 ? 145.887 116.862 173.852 1.00 110.16 ?  545 PHE E CZ    1 
ATOM 7419 N N     . SER D 2 175 ? 139.618 118.763 172.533 1.00 110.53 ?  546 SER E N     1 
ATOM 7420 C CA    . SER D 2 175 ? 139.267 120.171 172.649 1.00 110.53 ?  546 SER E CA    1 
ATOM 7421 C C     . SER D 2 175 ? 138.613 120.492 173.985 1.00 110.53 ?  546 SER E C     1 
ATOM 7422 O O     . SER D 2 175 ? 138.386 121.669 174.280 1.00 110.53 ?  546 SER E O     1 
ATOM 7423 C CB    . SER D 2 175 ? 138.339 120.581 171.507 1.00 110.53 ?  546 SER E CB    1 
ATOM 7424 O OG    . SER D 2 175 ? 138.999 120.472 170.260 1.00 110.53 ?  546 SER E OG    1 
ATOM 7425 N N     . ARG D 2 176 ? 138.300 119.479 174.790 1.00 114.74 ?  547 ARG E N     1 
ATOM 7426 C CA    . ARG D 2 176 ? 137.595 119.674 176.050 1.00 114.74 ?  547 ARG E CA    1 
ATOM 7427 C C     . ARG D 2 176 ? 138.520 119.945 177.231 1.00 114.74 ?  547 ARG E C     1 
ATOM 7428 O O     . ARG D 2 176 ? 138.027 120.081 178.355 1.00 114.74 ?  547 ARG E O     1 
ATOM 7429 C CB    . ARG D 2 176 ? 136.719 118.455 176.356 1.00 114.74 ?  547 ARG E CB    1 
ATOM 7430 C CG    . ARG D 2 176 ? 135.281 118.593 175.878 1.00 114.74 ?  547 ARG E CG    1 
ATOM 7431 C CD    . ARG D 2 176 ? 134.337 117.716 176.686 1.00 114.74 ?  547 ARG E CD    1 
ATOM 7432 N NE    . ARG D 2 176 ? 133.019 118.322 176.832 1.00 114.74 ?  547 ARG E NE    1 
ATOM 7433 C CZ    . ARG D 2 176 ? 132.102 117.924 177.704 1.00 114.74 ?  547 ARG E CZ    1 
ATOM 7434 N NH1   . ARG D 2 176 ? 132.322 116.910 178.524 1.00 114.74 1  547 ARG E NH1   1 
ATOM 7435 N NH2   . ARG D 2 176 ? 130.934 118.559 177.754 1.00 114.74 ?  547 ARG E NH2   1 
ATOM 7436 N N     . ILE D 2 177 ? 139.831 120.026 177.022 1.00 113.82 ?  548 ILE E N     1 
ATOM 7437 C CA    . ILE D 2 177 ? 140.744 120.249 178.141 1.00 113.82 ?  548 ILE E CA    1 
ATOM 7438 C C     . ILE D 2 177 ? 141.332 121.657 178.136 1.00 113.82 ?  548 ILE E C     1 
ATOM 7439 O O     . ILE D 2 177 ? 141.462 122.276 179.194 1.00 113.82 ?  548 ILE E O     1 
ATOM 7440 C CB    . ILE D 2 177 ? 141.856 119.179 178.166 1.00 113.82 ?  548 ILE E CB    1 
ATOM 7441 C CG1   . ILE D 2 177 ? 141.280 117.773 177.979 1.00 113.82 ?  548 ILE E CG1   1 
ATOM 7442 C CG2   . ILE D 2 177 ? 142.647 119.264 179.453 1.00 113.82 ?  548 ILE E CG2   1 
ATOM 7443 C CD1   . ILE D 2 177 ? 141.387 117.239 176.588 1.00 113.82 ?  548 ILE E CD1   1 
ATOM 7444 N N     . LEU D 2 178 ? 141.704 122.200 176.976 1.00 114.89 ?  549 LEU E N     1 
ATOM 7445 C CA    . LEU D 2 178 ? 142.443 123.460 176.978 1.00 114.89 ?  549 LEU E CA    1 
ATOM 7446 C C     . LEU D 2 178 ? 141.624 124.637 177.493 1.00 114.89 ?  549 LEU E C     1 
ATOM 7447 O O     . LEU D 2 178 ? 142.212 125.627 177.941 1.00 114.89 ?  549 LEU E O     1 
ATOM 7448 C CB    . LEU D 2 178 ? 142.980 123.806 175.583 1.00 114.89 ?  549 LEU E CB    1 
ATOM 7449 C CG    . LEU D 2 178 ? 142.096 124.004 174.347 1.00 114.89 ?  549 LEU E CG    1 
ATOM 7450 C CD1   . LEU D 2 178 ? 142.961 124.460 173.187 1.00 114.89 ?  549 LEU E CD1   1 
ATOM 7451 C CD2   . LEU D 2 178 ? 141.365 122.741 173.953 1.00 114.89 ?  549 LEU E CD2   1 
ATOM 7452 N N     . LEU D 2 179 ? 140.292 124.563 177.445 1.00 118.36 ?  550 LEU E N     1 
ATOM 7453 C CA    . LEU D 2 179 ? 139.495 125.685 177.931 1.00 118.36 ?  550 LEU E CA    1 
ATOM 7454 C C     . LEU D 2 179 ? 139.524 125.771 179.451 1.00 118.36 ?  550 LEU E C     1 
ATOM 7455 O O     . LEU D 2 179 ? 139.681 126.863 180.007 1.00 118.36 ?  550 LEU E O     1 
ATOM 7456 C CB    . LEU D 2 179 ? 138.045 125.591 177.444 1.00 118.36 ?  550 LEU E CB    1 
ATOM 7457 C CG    . LEU D 2 179 ? 137.167 124.365 177.713 1.00 118.36 ?  550 LEU E CG    1 
ATOM 7458 C CD1   . LEU D 2 179 ? 135.715 124.702 177.418 1.00 118.36 ?  550 LEU E CD1   1 
ATOM 7459 C CD2   . LEU D 2 179 ? 137.586 123.176 176.886 1.00 118.36 ?  550 LEU E CD2   1 
ATOM 7460 N N     . LEU D 2 180 ? 139.385 124.634 180.142 1.00 120.70 ?  551 LEU E N     1 
ATOM 7461 C CA    . LEU D 2 180 ? 139.387 124.658 181.600 1.00 120.70 ?  551 LEU E CA    1 
ATOM 7462 C C     . LEU D 2 180 ? 140.735 125.093 182.157 1.00 120.70 ?  551 LEU E C     1 
ATOM 7463 O O     . LEU D 2 180 ? 140.811 125.506 183.319 1.00 120.70 ?  551 LEU E O     1 
ATOM 7464 C CB    . LEU D 2 180 ? 138.966 123.288 182.153 1.00 120.70 ?  551 LEU E CB    1 
ATOM 7465 C CG    . LEU D 2 180 ? 139.660 121.946 181.863 1.00 120.70 ?  551 LEU E CG    1 
ATOM 7466 C CD1   . LEU D 2 180 ? 141.131 121.899 182.268 1.00 120.70 ?  551 LEU E CD1   1 
ATOM 7467 C CD2   . LEU D 2 180 ? 138.891 120.802 182.514 1.00 120.70 ?  551 LEU E CD2   1 
ATOM 7468 N N     . PHE D 2 181 ? 141.795 125.008 181.353 1.00 121.02 ?  552 PHE E N     1 
ATOM 7469 C CA    . PHE D 2 181 ? 143.071 125.611 181.706 1.00 121.02 ?  552 PHE E CA    1 
ATOM 7470 C C     . PHE D 2 181 ? 142.999 127.132 181.715 1.00 121.02 ?  552 PHE E C     1 
ATOM 7471 O O     . PHE D 2 181 ? 143.685 127.768 182.521 1.00 121.02 ?  552 PHE E O     1 
ATOM 7472 C CB    . PHE D 2 181 ? 144.152 125.137 180.729 1.00 121.02 ?  552 PHE E CB    1 
ATOM 7473 C CG    . PHE D 2 181 ? 145.551 125.201 181.280 1.00 121.02 ?  552 PHE E CG    1 
ATOM 7474 C CD1   . PHE D 2 181 ? 146.182 126.418 181.480 1.00 121.02 ?  552 PHE E CD1   1 
ATOM 7475 C CD2   . PHE D 2 181 ? 146.235 124.040 181.596 1.00 121.02 ?  552 PHE E CD2   1 
ATOM 7476 C CE1   . PHE D 2 181 ? 147.467 126.475 181.985 1.00 121.02 ?  552 PHE E CE1   1 
ATOM 7477 C CE2   . PHE D 2 181 ? 147.520 124.090 182.101 1.00 121.02 ?  552 PHE E CE2   1 
ATOM 7478 C CZ    . PHE D 2 181 ? 148.136 125.309 182.296 1.00 121.02 ?  552 PHE E CZ    1 
ATOM 7479 N N     . SER D 2 182 ? 142.169 127.722 180.858 1.00 119.03 ?  553 SER E N     1 
ATOM 7480 C CA    . SER D 2 182 ? 142.080 129.169 180.721 1.00 119.03 ?  553 SER E CA    1 
ATOM 7481 C C     . SER D 2 182 ? 141.328 129.838 181.864 1.00 119.03 ?  553 SER E C     1 
ATOM 7482 O O     . SER D 2 182 ? 141.408 131.063 182.001 1.00 119.03 ?  553 SER E O     1 
ATOM 7483 C CB    . SER D 2 182 ? 141.412 129.529 179.390 1.00 119.03 ?  553 SER E CB    1 
ATOM 7484 O OG    . SER D 2 182 ? 140.042 129.170 179.396 1.00 119.03 ?  553 SER E OG    1 
ATOM 7485 N N     . LEU D 2 183 ? 140.605 129.079 182.682 1.00 118.14 ?  554 LEU E N     1 
ATOM 7486 C CA    . LEU D 2 183 ? 139.941 129.654 183.848 1.00 118.14 ?  554 LEU E CA    1 
ATOM 7487 C C     . LEU D 2 183 ? 140.947 129.899 184.966 1.00 118.14 ?  554 LEU E C     1 
ATOM 7488 O O     . LEU D 2 183 ? 141.065 131.015 185.473 1.00 118.14 ?  554 LEU E O     1 
ATOM 7489 C CB    . LEU D 2 183 ? 138.808 128.751 184.353 1.00 118.14 ?  554 LEU E CB    1 
ATOM 7490 C CG    . LEU D 2 183 ? 137.511 128.599 183.546 1.00 118.14 ?  554 LEU E CG    1 
ATOM 7491 C CD1   . LEU D 2 183 ? 136.869 129.959 183.298 1.00 118.14 ?  554 LEU E CD1   1 
ATOM 7492 C CD2   . LEU D 2 183 ? 137.700 127.839 182.243 1.00 118.14 ?  554 LEU E CD2   1 
ATOM 7493 O OP3   . DC  E 3 1   ? 129.337 126.749 94.240  1.00 276.29 ?  1   DC  A OP3   1 
ATOM 7494 P P     . DC  E 3 1   ? 129.093 127.303 95.590  1.00 276.29 ?  1   DC  A P     1 
ATOM 7495 O OP1   . DC  E 3 1   ? 128.362 126.279 96.366  1.00 276.29 ?  1   DC  A OP1   1 
ATOM 7496 O OP2   . DC  E 3 1   ? 128.488 128.641 95.418  1.00 276.29 -1 1   DC  A OP2   1 
ATOM 7497 O "O5'" . DC  E 3 1   ? 130.513 127.525 96.287  1.00 276.29 ?  1   DC  A "O5'" 1 
ATOM 7498 C "C5'" . DC  E 3 1   ? 131.704 127.116 95.625  1.00 276.29 ?  1   DC  A "C5'" 1 
ATOM 7499 C "C4'" . DC  E 3 1   ? 132.919 127.801 96.227  1.00 276.29 ?  1   DC  A "C4'" 1 
ATOM 7500 O "O4'" . DC  E 3 1   ? 132.749 129.240 96.150  1.00 276.29 ?  1   DC  A "O4'" 1 
ATOM 7501 C "C3'" . DC  E 3 1   ? 133.177 127.487 97.698  1.00 276.29 ?  1   DC  A "C3'" 1 
ATOM 7502 O "O3'" . DC  E 3 1   ? 134.573 127.458 97.951  1.00 276.29 ?  1   DC  A "O3'" 1 
ATOM 7503 C "C2'" . DC  E 3 1   ? 132.506 128.652 98.416  1.00 276.29 ?  1   DC  A "C2'" 1 
ATOM 7504 C "C1'" . DC  E 3 1   ? 132.763 129.799 97.448  1.00 276.29 ?  1   DC  A "C1'" 1 
ATOM 7505 N N1    . DC  E 3 1   ? 131.728 130.866 97.511  1.00 276.29 ?  1   DC  A N1    1 
ATOM 7506 C C2    . DC  E 3 1   ? 132.082 132.191 97.243  1.00 276.29 ?  1   DC  A C2    1 
ATOM 7507 O O2    . DC  E 3 1   ? 133.256 132.455 96.954  1.00 276.29 ?  1   DC  A O2    1 
ATOM 7508 N N3    . DC  E 3 1   ? 131.127 133.151 97.306  1.00 276.29 ?  1   DC  A N3    1 
ATOM 7509 C C4    . DC  E 3 1   ? 129.872 132.825 97.622  1.00 276.29 ?  1   DC  A C4    1 
ATOM 7510 N N4    . DC  E 3 1   ? 128.964 133.804 97.672  1.00 276.29 ?  1   DC  A N4    1 
ATOM 7511 C C5    . DC  E 3 1   ? 129.493 131.479 97.899  1.00 276.29 ?  1   DC  A C5    1 
ATOM 7512 C C6    . DC  E 3 1   ? 130.443 130.542 97.834  1.00 276.29 ?  1   DC  A C6    1 
ATOM 7513 P P     . DG  E 3 2   ? 135.167 126.491 99.089  1.00 271.43 ?  2   DG  A P     1 
ATOM 7514 O OP1   . DG  E 3 2   ? 135.298 125.138 98.504  1.00 271.43 ?  2   DG  A OP1   1 
ATOM 7515 O OP2   . DG  E 3 2   ? 134.361 126.690 100.314 1.00 271.43 -1 2   DG  A OP2   1 
ATOM 7516 O "O5'" . DG  E 3 2   ? 136.627 127.080 99.364  1.00 271.43 ?  2   DG  A "O5'" 1 
ATOM 7517 C "C5'" . DG  E 3 2   ? 137.548 127.222 98.291  1.00 271.43 ?  2   DG  A "C5'" 1 
ATOM 7518 C "C4'" . DG  E 3 2   ? 138.299 128.537 98.394  1.00 271.43 ?  2   DG  A "C4'" 1 
ATOM 7519 O "O4'" . DG  E 3 2   ? 137.372 129.643 98.220  1.00 271.43 ?  2   DG  A "O4'" 1 
ATOM 7520 C "C3'" . DG  E 3 2   ? 139.005 128.779 99.728  1.00 271.43 ?  2   DG  A "C3'" 1 
ATOM 7521 O "O3'" . DG  E 3 2   ? 140.272 129.378 99.499  1.00 271.43 ?  2   DG  A "O3'" 1 
ATOM 7522 C "C2'" . DG  E 3 2   ? 138.056 129.730 100.455 1.00 271.43 ?  2   DG  A "C2'" 1 
ATOM 7523 C "C1'" . DG  E 3 2   ? 137.497 130.543 99.299  1.00 271.43 ?  2   DG  A "C1'" 1 
ATOM 7524 N N9    . DG  E 3 2   ? 136.183 131.118 99.572  1.00 271.43 ?  2   DG  A N9    1 
ATOM 7525 C C8    . DG  E 3 2   ? 135.060 130.450 99.996  1.00 271.43 ?  2   DG  A C8    1 
ATOM 7526 N N7    . DG  E 3 2   ? 134.024 131.224 100.157 1.00 271.43 ?  2   DG  A N7    1 
ATOM 7527 C C5    . DG  E 3 2   ? 134.487 132.488 99.815  1.00 271.43 ?  2   DG  A C5    1 
ATOM 7528 C C6    . DG  E 3 2   ? 133.812 133.731 99.793  1.00 271.43 ?  2   DG  A C6    1 
ATOM 7529 O O6    . DG  E 3 2   ? 132.631 133.969 100.084 1.00 271.43 ?  2   DG  A O6    1 
ATOM 7530 N N1    . DG  E 3 2   ? 134.651 134.766 99.387  1.00 271.43 ?  2   DG  A N1    1 
ATOM 7531 C C2    . DG  E 3 2   ? 135.973 134.617 99.042  1.00 271.43 ?  2   DG  A C2    1 
ATOM 7532 N N2    . DG  E 3 2   ? 136.620 135.732 98.675  1.00 271.43 ?  2   DG  A N2    1 
ATOM 7533 N N3    . DG  E 3 2   ? 136.618 133.457 99.057  1.00 271.43 ?  2   DG  A N3    1 
ATOM 7534 C C4    . DG  E 3 2   ? 135.815 132.439 99.451  1.00 271.43 ?  2   DG  A C4    1 
ATOM 7535 P P     . DA  E 3 3   ? 141.385 129.400 100.658 1.00 273.97 ?  3   DA  A P     1 
ATOM 7536 O OP1   . DA  E 3 3   ? 142.602 128.755 100.118 1.00 273.97 ?  3   DA  A OP1   1 
ATOM 7537 O OP2   . DA  E 3 3   ? 140.772 128.882 101.901 1.00 273.97 -1 3   DA  A OP2   1 
ATOM 7538 O "O5'" . DA  E 3 3   ? 141.680 130.956 100.865 1.00 273.97 ?  3   DA  A "O5'" 1 
ATOM 7539 C "C5'" . DA  E 3 3   ? 142.051 131.756 99.751  1.00 273.97 ?  3   DA  A "C5'" 1 
ATOM 7540 C "C4'" . DA  E 3 3   ? 141.881 133.232 100.061 1.00 273.97 ?  3   DA  A "C4'" 1 
ATOM 7541 O "O4'" . DA  E 3 3   ? 140.469 133.566 100.103 1.00 273.97 ?  3   DA  A "O4'" 1 
ATOM 7542 C "C3'" . DA  E 3 3   ? 142.471 133.686 101.396 1.00 273.97 ?  3   DA  A "C3'" 1 
ATOM 7543 O "O3'" . DA  E 3 3   ? 143.184 134.898 101.213 1.00 273.97 ?  3   DA  A "O3'" 1 
ATOM 7544 C "C2'" . DA  E 3 3   ? 141.241 133.879 102.284 1.00 273.97 ?  3   DA  A "C2'" 1 
ATOM 7545 C "C1'" . DA  E 3 3   ? 140.191 134.303 101.271 1.00 273.97 ?  3   DA  A "C1'" 1 
ATOM 7546 N N9    . DA  E 3 3   ? 138.822 134.002 101.682 1.00 273.97 ?  3   DA  A N9    1 
ATOM 7547 C C8    . DA  E 3 3   ? 138.311 132.777 102.005 1.00 273.97 ?  3   DA  A C8    1 
ATOM 7548 N N7    . DA  E 3 3   ? 137.041 132.801 102.330 1.00 273.97 ?  3   DA  A N7    1 
ATOM 7549 C C5    . DA  E 3 3   ? 136.692 134.136 102.210 1.00 273.97 ?  3   DA  A C5    1 
ATOM 7550 C C6    . DA  E 3 3   ? 135.479 134.822 102.414 1.00 273.97 ?  3   DA  A C6    1 
ATOM 7551 N N6    . DA  E 3 3   ? 134.350 134.221 102.804 1.00 273.97 ?  3   DA  A N6    1 
ATOM 7552 N N1    . DA  E 3 3   ? 135.472 136.155 102.206 1.00 273.97 ?  3   DA  A N1    1 
ATOM 7553 C C2    . DA  E 3 3   ? 136.604 136.753 101.817 1.00 273.97 ?  3   DA  A C2    1 
ATOM 7554 N N3    . DA  E 3 3   ? 137.803 136.215 101.593 1.00 273.97 ?  3   DA  A N3    1 
ATOM 7555 C C4    . DA  E 3 3   ? 137.778 134.890 101.809 1.00 273.97 ?  3   DA  A C4    1 
ATOM 7556 P P     . DA  E 3 4   ? 144.131 135.469 102.377 1.00 261.19 ?  4   DA  A P     1 
ATOM 7557 O OP1   . DA  E 3 4   ? 145.394 135.912 101.746 1.00 261.19 ?  4   DA  A OP1   1 
ATOM 7558 O OP2   . DA  E 3 4   ? 144.165 134.475 103.473 1.00 261.19 -1 4   DA  A OP2   1 
ATOM 7559 O "O5'" . DA  E 3 4   ? 143.341 136.755 102.900 1.00 261.19 ?  4   DA  A "O5'" 1 
ATOM 7560 C "C5'" . DA  E 3 4   ? 142.881 137.723 101.969 1.00 261.19 ?  4   DA  A "C5'" 1 
ATOM 7561 C "C4'" . DA  E 3 4   ? 141.988 138.743 102.647 1.00 261.19 ?  4   DA  A "C4'" 1 
ATOM 7562 O "O4'" . DA  E 3 4   ? 140.652 138.198 102.805 1.00 261.19 ?  4   DA  A "O4'" 1 
ATOM 7563 C "C3'" . DA  E 3 4   ? 142.445 139.176 104.039 1.00 261.19 ?  4   DA  A "C3'" 1 
ATOM 7564 O "O3'" . DA  E 3 4   ? 142.363 140.590 104.147 1.00 261.19 ?  4   DA  A "O3'" 1 
ATOM 7565 C "C2'" . DA  E 3 4   ? 141.463 138.468 104.978 1.00 261.19 ?  4   DA  A "C2'" 1 
ATOM 7566 C "C1'" . DA  E 3 4   ? 140.207 138.403 104.126 1.00 261.19 ?  4   DA  A "C1'" 1 
ATOM 7567 N N9    . DA  E 3 4   ? 139.313 137.304 104.476 1.00 261.19 ?  4   DA  A N9    1 
ATOM 7568 C C8    . DA  E 3 4   ? 139.635 135.980 104.577 1.00 261.19 ?  4   DA  A C8    1 
ATOM 7569 N N7    . DA  E 3 4   ? 138.622 135.210 104.897 1.00 261.19 ?  4   DA  A N7    1 
ATOM 7570 C C5    . DA  E 3 4   ? 137.559 136.090 105.007 1.00 261.19 ?  4   DA  A C5    1 
ATOM 7571 C C6    . DA  E 3 4   ? 136.199 135.901 105.325 1.00 261.19 ?  4   DA  A C6    1 
ATOM 7572 N N6    . DA  E 3 4   ? 135.666 134.706 105.596 1.00 261.19 ?  4   DA  A N6    1 
ATOM 7573 N N1    . DA  E 3 4   ? 135.405 136.992 105.347 1.00 261.19 ?  4   DA  A N1    1 
ATOM 7574 C C2    . DA  E 3 4   ? 135.942 138.186 105.072 1.00 261.19 ?  4   DA  A C2    1 
ATOM 7575 N N3    . DA  E 3 4   ? 137.203 138.488 104.764 1.00 261.19 ?  4   DA  A N3    1 
ATOM 7576 C C4    . DA  E 3 4   ? 137.966 137.385 104.749 1.00 261.19 ?  4   DA  A C4    1 
ATOM 7577 P P     . DT  E 3 5   ? 142.710 141.325 105.532 1.00 236.31 ?  5   DT  A P     1 
ATOM 7578 O OP1   . DT  E 3 5   ? 143.178 142.690 105.207 1.00 236.31 ?  5   DT  A OP1   1 
ATOM 7579 O OP2   . DT  E 3 5   ? 143.574 140.426 106.331 1.00 236.31 -1 5   DT  A OP2   1 
ATOM 7580 O "O5'" . DT  E 3 5   ? 141.293 141.432 106.259 1.00 236.31 ?  5   DT  A "O5'" 1 
ATOM 7581 C "C5'" . DT  E 3 5   ? 140.157 141.871 105.525 1.00 236.31 ?  5   DT  A "C5'" 1 
ATOM 7582 C "C4'" . DT  E 3 5   ? 138.992 142.139 106.455 1.00 236.31 ?  5   DT  A "C4'" 1 
ATOM 7583 O "O4'" . DT  E 3 5   ? 138.169 140.949 106.564 1.00 236.31 ?  5   DT  A "O4'" 1 
ATOM 7584 C "C3'" . DT  E 3 5   ? 139.391 142.520 107.880 1.00 236.31 ?  5   DT  A "C3'" 1 
ATOM 7585 O "O3'" . DT  E 3 5   ? 138.615 143.622 108.318 1.00 236.31 ?  5   DT  A "O3'" 1 
ATOM 7586 C "C2'" . DT  E 3 5   ? 139.088 141.256 108.685 1.00 236.31 ?  5   DT  A "C2'" 1 
ATOM 7587 C "C1'" . DT  E 3 5   ? 137.910 140.678 107.922 1.00 236.31 ?  5   DT  A "C1'" 1 
ATOM 7588 N N1    . DT  E 3 5   ? 137.756 139.204 108.081 1.00 236.31 ?  5   DT  A N1    1 
ATOM 7589 C C2    . DT  E 3 5   ? 136.507 138.680 108.319 1.00 236.31 ?  5   DT  A C2    1 
ATOM 7590 O O2    . DT  E 3 5   ? 135.503 139.362 108.413 1.00 236.31 ?  5   DT  A O2    1 
ATOM 7591 N N3    . DT  E 3 5   ? 136.472 137.316 108.443 1.00 236.31 ?  5   DT  A N3    1 
ATOM 7592 C C4    . DT  E 3 5   ? 137.540 136.443 108.355 1.00 236.31 ?  5   DT  A C4    1 
ATOM 7593 O O4    . DT  E 3 5   ? 137.407 135.230 108.482 1.00 236.31 ?  5   DT  A O4    1 
ATOM 7594 C C5    . DT  E 3 5   ? 138.821 137.058 108.104 1.00 236.31 ?  5   DT  A C5    1 
ATOM 7595 C C7    . DT  E 3 5   ? 140.054 136.211 107.989 1.00 236.31 ?  5   DT  A C7    1 
ATOM 7596 C C6    . DT  E 3 5   ? 138.866 138.392 107.979 1.00 236.31 ?  5   DT  A C6    1 
ATOM 7597 P P     . DT  E 3 6   ? 139.139 144.556 109.515 1.00 218.59 ?  6   DT  A P     1 
ATOM 7598 O OP1   . DT  E 3 6   ? 139.148 145.953 109.026 1.00 218.59 ?  6   DT  A OP1   1 
ATOM 7599 O OP2   . DT  E 3 6   ? 140.383 143.957 110.047 1.00 218.59 -1 6   DT  A OP2   1 
ATOM 7600 O "O5'" . DT  E 3 6   ? 138.002 144.405 110.626 1.00 218.59 ?  6   DT  A "O5'" 1 
ATOM 7601 C "C5'" . DT  E 3 6   ? 136.636 144.511 110.250 1.00 218.59 ?  6   DT  A "C5'" 1 
ATOM 7602 C "C4'" . DT  E 3 6   ? 135.757 143.683 111.167 1.00 218.59 ?  6   DT  A "C4'" 1 
ATOM 7603 O "O4'" . DT  E 3 6   ? 136.056 142.276 110.995 1.00 218.59 ?  6   DT  A "O4'" 1 
ATOM 7604 C "C3'" . DT  E 3 6   ? 135.918 143.981 112.660 1.00 218.59 ?  6   DT  A "C3'" 1 
ATOM 7605 O "O3'" . DT  E 3 6   ? 134.651 144.289 113.224 1.00 218.59 ?  6   DT  A "O3'" 1 
ATOM 7606 C "C2'" . DT  E 3 6   ? 136.505 142.687 113.241 1.00 218.59 ?  6   DT  A "C2'" 1 
ATOM 7607 C "C1'" . DT  E 3 6   ? 136.027 141.642 112.248 1.00 218.59 ?  6   DT  A "C1'" 1 
ATOM 7608 N N1    . DT  E 3 6   ? 136.901 140.435 112.180 1.00 218.59 ?  6   DT  A N1    1 
ATOM 7609 C C2    . DT  E 3 6   ? 136.338 139.188 112.321 1.00 218.59 ?  6   DT  A C2    1 
ATOM 7610 O O2    . DT  E 3 6   ? 135.148 139.010 112.508 1.00 218.59 ?  6   DT  A O2    1 
ATOM 7611 N N3    . DT  E 3 6   ? 137.224 138.148 112.236 1.00 218.59 ?  6   DT  A N3    1 
ATOM 7612 C C4    . DT  E 3 6   ? 138.588 138.227 112.028 1.00 218.59 ?  6   DT  A C4    1 
ATOM 7613 O O4    . DT  E 3 6   ? 139.302 137.232 111.967 1.00 218.59 ?  6   DT  A O4    1 
ATOM 7614 C C5    . DT  E 3 6   ? 139.114 139.564 111.887 1.00 218.59 ?  6   DT  A C5    1 
ATOM 7615 C C7    . DT  E 3 6   ? 140.581 139.777 111.658 1.00 218.59 ?  6   DT  A C7    1 
ATOM 7616 C C6    . DT  E 3 6   ? 138.255 140.591 111.970 1.00 218.59 ?  6   DT  A C6    1 
ATOM 7617 P P     . DT  E 3 7   ? 134.521 144.669 114.779 1.00 206.10 ?  7   DT  A P     1 
ATOM 7618 O OP1   . DT  E 3 7   ? 133.407 145.634 114.907 1.00 206.10 ?  7   DT  A OP1   1 
ATOM 7619 O OP2   . DT  E 3 7   ? 135.864 145.029 115.285 1.00 206.10 -1 7   DT  A OP2   1 
ATOM 7620 O "O5'" . DT  E 3 7   ? 134.084 143.293 115.463 1.00 206.10 ?  7   DT  A "O5'" 1 
ATOM 7621 C "C5'" . DT  E 3 7   ? 133.005 142.547 114.913 1.00 206.10 ?  7   DT  A "C5'" 1 
ATOM 7622 C "C4'" . DT  E 3 7   ? 132.828 141.231 115.646 1.00 206.10 ?  7   DT  A "C4'" 1 
ATOM 7623 O "O4'" . DT  E 3 7   ? 133.903 140.322 115.287 1.00 206.10 ?  7   DT  A "O4'" 1 
ATOM 7624 C "C3'" . DT  E 3 7   ? 132.849 141.334 117.172 1.00 206.10 ?  7   DT  A "C3'" 1 
ATOM 7625 O "O3'" . DT  E 3 7   ? 131.829 140.514 117.722 1.00 206.10 ?  7   DT  A "O3'" 1 
ATOM 7626 C "C2'" . DT  E 3 7   ? 134.240 140.820 117.535 1.00 206.10 ?  7   DT  A "C2'" 1 
ATOM 7627 C "C1'" . DT  E 3 7   ? 134.458 139.774 116.458 1.00 206.10 ?  7   DT  A "C1'" 1 
ATOM 7628 N N1    . DT  E 3 7   ? 135.891 139.466 116.204 1.00 206.10 ?  7   DT  A N1    1 
ATOM 7629 C C2    . DT  E 3 7   ? 136.294 138.155 116.157 1.00 206.10 ?  7   DT  A C2    1 
ATOM 7630 O O2    . DT  E 3 7   ? 135.534 137.218 116.317 1.00 206.10 ?  7   DT  A O2    1 
ATOM 7631 N N3    . DT  E 3 7   ? 137.629 137.976 115.915 1.00 206.10 ?  7   DT  A N3    1 
ATOM 7632 C C4    . DT  E 3 7   ? 138.582 138.957 115.720 1.00 206.10 ?  7   DT  A C4    1 
ATOM 7633 O O4    . DT  E 3 7   ? 139.761 138.693 115.509 1.00 206.10 ?  7   DT  A O4    1 
ATOM 7634 C C5    . DT  E 3 7   ? 138.092 140.313 115.782 1.00 206.10 ?  7   DT  A C5    1 
ATOM 7635 C C7    . DT  E 3 7   ? 139.033 141.464 115.586 1.00 206.10 ?  7   DT  A C7    1 
ATOM 7636 C C6    . DT  E 3 7   ? 136.785 140.500 116.019 1.00 206.10 ?  7   DT  A C6    1 
ATOM 7637 P P     . DC  E 3 8   ? 131.441 140.628 119.277 1.00 199.10 ?  8   DC  A P     1 
ATOM 7638 O OP1   . DC  E 3 8   ? 129.975 140.806 119.352 1.00 199.10 ?  8   DC  A OP1   1 
ATOM 7639 O OP2   . DC  E 3 8   ? 132.333 141.623 119.912 1.00 199.10 -1 8   DC  A OP2   1 
ATOM 7640 O "O5'" . DC  E 3 8   ? 131.811 139.187 119.862 1.00 199.10 ?  8   DC  A "O5'" 1 
ATOM 7641 C "C5'" . DC  E 3 8   ? 131.235 138.025 119.282 1.00 199.10 ?  8   DC  A "C5'" 1 
ATOM 7642 C "C4'" . DC  E 3 8   ? 131.996 136.779 119.695 1.00 199.10 ?  8   DC  A "C4'" 1 
ATOM 7643 O "O4'" . DC  E 3 8   ? 133.353 136.843 119.182 1.00 199.10 ?  8   DC  A "O4'" 1 
ATOM 7644 C "C3'" . DC  E 3 8   ? 132.117 136.563 121.203 1.00 199.10 ?  8   DC  A "C3'" 1 
ATOM 7645 O "O3'" . DC  E 3 8   ? 131.867 135.200 121.515 1.00 199.10 ?  8   DC  A "O3'" 1 
ATOM 7646 C "C2'" . DC  E 3 8   ? 133.563 136.956 121.504 1.00 199.10 ?  8   DC  A "C2'" 1 
ATOM 7647 C "C1'" . DC  E 3 8   ? 134.263 136.556 120.217 1.00 199.10 ?  8   DC  A "C1'" 1 
ATOM 7648 N N1    . DC  E 3 8   ? 135.514 137.315 119.960 1.00 199.10 ?  8   DC  A N1    1 
ATOM 7649 C C2    . DC  E 3 8   ? 136.706 136.625 119.725 1.00 199.10 ?  8   DC  A C2    1 
ATOM 7650 O O2    . DC  E 3 8   ? 136.699 135.389 119.740 1.00 199.10 ?  8   DC  A O2    1 
ATOM 7651 N N3    . DC  E 3 8   ? 137.838 137.332 119.487 1.00 199.10 ?  8   DC  A N3    1 
ATOM 7652 C C4    . DC  E 3 8   ? 137.802 138.665 119.479 1.00 199.10 ?  8   DC  A C4    1 
ATOM 7653 N N4    . DC  E 3 8   ? 138.943 139.320 119.240 1.00 199.10 ?  8   DC  A N4    1 
ATOM 7654 C C5    . DC  E 3 8   ? 136.597 139.385 119.716 1.00 199.10 ?  8   DC  A C5    1 
ATOM 7655 C C6    . DC  E 3 8   ? 135.488 138.677 119.949 1.00 199.10 ?  8   DC  A C6    1 
ATOM 7656 P P     . DT  E 3 9   ? 131.786 134.718 123.044 1.00 197.29 ?  9   DT  A P     1 
ATOM 7657 O OP1   . DT  E 3 9   ? 130.721 133.694 123.130 1.00 197.29 ?  9   DT  A OP1   1 
ATOM 7658 O OP2   . DT  E 3 9   ? 131.719 135.920 123.904 1.00 197.29 -1 9   DT  A OP2   1 
ATOM 7659 O "O5'" . DT  E 3 9   ? 133.197 134.010 123.293 1.00 197.29 ?  9   DT  A "O5'" 1 
ATOM 7660 C "C5'" . DT  E 3 9   ? 133.614 132.951 122.442 1.00 197.29 ?  9   DT  A "C5'" 1 
ATOM 7661 C "C4'" . DT  E 3 9   ? 135.007 132.478 122.811 1.00 197.29 ?  9   DT  A "C4'" 1 
ATOM 7662 O "O4'" . DT  E 3 9   ? 135.988 133.450 122.361 1.00 197.29 ?  9   DT  A "O4'" 1 
ATOM 7663 C "C3'" . DT  E 3 9   ? 135.250 132.290 124.311 1.00 197.29 ?  9   DT  A "C3'" 1 
ATOM 7664 O "O3'" . DT  E 3 9   ? 135.966 131.085 124.538 1.00 197.29 ?  9   DT  A "O3'" 1 
ATOM 7665 C "C2'" . DT  E 3 9   ? 136.089 133.511 124.679 1.00 197.29 ?  9   DT  A "C2'" 1 
ATOM 7666 C "C1'" . DT  E 3 9   ? 136.893 133.700 123.408 1.00 197.29 ?  9   DT  A "C1'" 1 
ATOM 7667 N N1    . DT  E 3 9   ? 137.444 135.070 123.250 1.00 197.29 ?  9   DT  A N1    1 
ATOM 7668 C C2    . DT  E 3 9   ? 138.775 135.223 122.951 1.00 197.29 ?  9   DT  A C2    1 
ATOM 7669 O O2    . DT  E 3 9   ? 139.537 134.286 122.800 1.00 197.29 ?  9   DT  A O2    1 
ATOM 7670 N N3    . DT  E 3 9   ? 139.188 136.522 122.830 1.00 197.29 ?  9   DT  A N3    1 
ATOM 7671 C C4    . DT  E 3 9   ? 138.419 137.659 122.977 1.00 197.29 ?  9   DT  A C4    1 
ATOM 7672 O O4    . DT  E 3 9   ? 138.884 138.787 122.847 1.00 197.29 ?  9   DT  A O4    1 
ATOM 7673 C C5    . DT  E 3 9   ? 137.030 137.429 123.293 1.00 197.29 ?  9   DT  A C5    1 
ATOM 7674 C C7    . DT  E 3 9   ? 136.098 138.588 123.479 1.00 197.29 ?  9   DT  A C7    1 
ATOM 7675 C C6    . DT  E 3 9   ? 136.615 136.159 123.415 1.00 197.29 ?  9   DT  A C6    1 
ATOM 7676 P P     . DA  E 3 10  ? 135.882 130.347 125.963 1.00 201.15 ?  10  DA  A P     1 
ATOM 7677 O OP1   . DA  E 3 10  ? 134.943 129.213 125.822 1.00 201.15 ?  10  DA  A OP1   1 
ATOM 7678 O OP2   . DA  E 3 10  ? 135.641 131.375 127.000 1.00 201.15 -1 10  DA  A OP2   1 
ATOM 7679 O "O5'" . DA  E 3 10  ? 137.358 129.772 126.180 1.00 201.15 ?  10  DA  A "O5'" 1 
ATOM 7680 C "C5'" . DA  E 3 10  ? 137.892 128.826 125.262 1.00 201.15 ?  10  DA  A "C5'" 1 
ATOM 7681 C "C4'" . DA  E 3 10  ? 139.411 128.870 125.256 1.00 201.15 ?  10  DA  A "C4'" 1 
ATOM 7682 O "O4'" . DA  E 3 10  ? 139.858 130.178 124.817 1.00 201.15 ?  10  DA  A "O4'" 1 
ATOM 7683 C "C3'" . DA  E 3 10  ? 140.073 128.627 126.608 1.00 201.15 ?  10  DA  A "C3'" 1 
ATOM 7684 O "O3'" . DA  E 3 10  ? 141.265 127.876 126.434 1.00 201.15 ?  10  DA  A "O3'" 1 
ATOM 7685 C "C2'" . DA  E 3 10  ? 140.365 130.037 127.112 1.00 201.15 ?  10  DA  A "C2'" 1 
ATOM 7686 C "C1'" . DA  E 3 10  ? 140.648 130.787 125.817 1.00 201.15 ?  10  DA  A "C1'" 1 
ATOM 7687 N N9    . DA  E 3 10  ? 140.285 132.197 125.881 1.00 201.15 ?  10  DA  A N9    1 
ATOM 7688 C C8    . DA  E 3 10  ? 139.059 132.715 126.185 1.00 201.15 ?  10  DA  A C8    1 
ATOM 7689 N N7    . DA  E 3 10  ? 139.017 134.024 126.166 1.00 201.15 ?  10  DA  A N7    1 
ATOM 7690 C C5    . DA  E 3 10  ? 140.306 134.392 125.825 1.00 201.15 ?  10  DA  A C5    1 
ATOM 7691 C C6    . DA  E 3 10  ? 140.913 135.646 125.639 1.00 201.15 ?  10  DA  A C6    1 
ATOM 7692 N N6    . DA  E 3 10  ? 140.262 136.803 125.780 1.00 201.15 ?  10  DA  A N6    1 
ATOM 7693 N N1    . DA  E 3 10  ? 142.219 135.665 125.301 1.00 201.15 ?  10  DA  A N1    1 
ATOM 7694 C C2    . DA  E 3 10  ? 142.865 134.502 125.160 1.00 201.15 ?  10  DA  A C2    1 
ATOM 7695 N N3    . DA  E 3 10  ? 142.401 133.262 125.310 1.00 201.15 ?  10  DA  A N3    1 
ATOM 7696 C C4    . DA  E 3 10  ? 141.102 133.278 125.645 1.00 201.15 ?  10  DA  A C4    1 
ATOM 7697 P P     . DG  E 3 11  ? 142.128 127.420 127.709 1.00 209.87 ?  11  DG  A P     1 
ATOM 7698 O OP1   . DG  E 3 11  ? 142.748 126.116 127.386 1.00 209.87 ?  11  DG  A OP1   1 
ATOM 7699 O OP2   . DG  E 3 11  ? 141.273 127.548 128.910 1.00 209.87 -1 11  DG  A OP2   1 
ATOM 7700 O "O5'" . DG  E 3 11  ? 143.278 128.525 127.803 1.00 209.87 ?  11  DG  A "O5'" 1 
ATOM 7701 C "C5'" . DG  E 3 11  ? 144.141 128.744 126.695 1.00 209.87 ?  11  DG  A "C5'" 1 
ATOM 7702 C "C4'" . DG  E 3 11  ? 145.206 129.769 127.036 1.00 209.87 ?  11  DG  A "C4'" 1 
ATOM 7703 O "O4'" . DG  E 3 11  ? 144.648 131.106 126.933 1.00 209.87 ?  11  DG  A "O4'" 1 
ATOM 7704 C "C3'" . DG  E 3 11  ? 145.782 129.652 128.449 1.00 209.87 ?  11  DG  A "C3'" 1 
ATOM 7705 O "O3'" . DG  E 3 11  ? 147.194 129.796 128.411 1.00 209.87 ?  11  DG  A "O3'" 1 
ATOM 7706 C "C2'" . DG  E 3 11  ? 145.120 130.810 129.193 1.00 209.87 ?  11  DG  A "C2'" 1 
ATOM 7707 C "C1'" . DG  E 3 11  ? 144.988 131.840 128.085 1.00 209.87 ?  11  DG  A "C1'" 1 
ATOM 7708 N N9    . DG  E 3 11  ? 143.944 132.829 128.332 1.00 209.87 ?  11  DG  A N9    1 
ATOM 7709 C C8    . DG  E 3 11  ? 142.636 132.585 128.673 1.00 209.87 ?  11  DG  A C8    1 
ATOM 7710 N N7    . DG  E 3 11  ? 141.931 133.669 128.833 1.00 209.87 ?  11  DG  A N7    1 
ATOM 7711 C C5    . DG  E 3 11  ? 142.827 134.699 128.583 1.00 209.87 ?  11  DG  A C5    1 
ATOM 7712 C C6    . DG  E 3 11  ? 142.635 136.100 128.604 1.00 209.87 ?  11  DG  A C6    1 
ATOM 7713 O O6    . DG  E 3 11  ? 141.598 136.728 128.858 1.00 209.87 ?  11  DG  A O6    1 
ATOM 7714 N N1    . DG  E 3 11  ? 143.805 136.785 128.290 1.00 209.87 ?  11  DG  A N1    1 
ATOM 7715 C C2    . DG  E 3 11  ? 145.008 136.192 127.993 1.00 209.87 ?  11  DG  A C2    1 
ATOM 7716 N N2    . DG  E 3 11  ? 146.026 137.019 127.715 1.00 209.87 ?  11  DG  A N2    1 
ATOM 7717 N N3    . DG  E 3 11  ? 145.202 134.880 127.969 1.00 209.87 ?  11  DG  A N3    1 
ATOM 7718 C C4    . DG  E 3 11  ? 144.072 134.198 128.274 1.00 209.87 ?  11  DG  A C4    1 
ATOM 7719 P P     . DA  E 3 12  ? 148.094 129.290 129.643 1.00 217.46 ?  12  DA  A P     1 
ATOM 7720 O OP1   . DA  E 3 12  ? 149.016 128.256 129.124 1.00 217.46 ?  12  DA  A OP1   1 
ATOM 7721 O OP2   . DA  E 3 12  ? 147.192 128.969 130.771 1.00 217.46 -1 12  DA  A OP2   1 
ATOM 7722 O "O5'" . DA  E 3 12  ? 148.946 130.582 130.045 1.00 217.46 ?  12  DA  A "O5'" 1 
ATOM 7723 C "C5'" . DA  E 3 12  ? 149.809 131.183 129.091 1.00 217.46 ?  12  DA  A "C5'" 1 
ATOM 7724 C "C4'" . DA  E 3 12  ? 149.974 132.666 129.367 1.00 217.46 ?  12  DA  A "C4'" 1 
ATOM 7725 O "O4'" . DA  E 3 12  ? 148.675 133.311 129.344 1.00 217.46 ?  12  DA  A "O4'" 1 
ATOM 7726 C "C3'" . DA  E 3 12  ? 150.603 133.008 130.722 1.00 217.46 ?  12  DA  A "C3'" 1 
ATOM 7727 O "O3'" . DA  E 3 12  ? 151.668 133.932 130.543 1.00 217.46 ?  12  DA  A "O3'" 1 
ATOM 7728 C "C2'" . DA  E 3 12  ? 149.451 133.622 131.518 1.00 217.46 ?  12  DA  A "C2'" 1 
ATOM 7729 C "C1'" . DA  E 3 12  ? 148.585 134.211 130.419 1.00 217.46 ?  12  DA  A "C1'" 1 
ATOM 7730 N N9    . DA  E 3 12  ? 147.183 134.337 130.801 1.00 217.46 ?  12  DA  A N9    1 
ATOM 7731 C C8    . DA  E 3 12  ? 146.314 133.322 131.080 1.00 217.46 ?  12  DA  A C8    1 
ATOM 7732 N N7    . DA  E 3 12  ? 145.110 133.729 131.402 1.00 217.46 ?  12  DA  A N7    1 
ATOM 7733 C C5    . DA  E 3 12  ? 145.198 135.108 131.334 1.00 217.46 ?  12  DA  A C5    1 
ATOM 7734 C C6    . DA  E 3 12  ? 144.259 136.129 131.564 1.00 217.46 ?  12  DA  A C6    1 
ATOM 7735 N N6    . DA  E 3 12  ? 142.994 135.897 131.924 1.00 217.46 ?  12  DA  A N6    1 
ATOM 7736 N N1    . DA  E 3 12  ? 144.672 137.403 131.410 1.00 217.46 ?  12  DA  A N1    1 
ATOM 7737 C C2    . DA  E 3 12  ? 145.939 137.631 131.047 1.00 217.46 ?  12  DA  A C2    1 
ATOM 7738 N N3    . DA  E 3 12  ? 146.911 136.755 130.803 1.00 217.46 ?  12  DA  A N3    1 
ATOM 7739 C C4    . DA  E 3 12  ? 146.470 135.500 130.964 1.00 217.46 ?  12  DA  A C4    1 
ATOM 7740 P P     . DC  E 3 13  ? 152.531 134.432 131.803 1.00 224.94 ?  13  DC  A P     1 
ATOM 7741 O OP1   . DC  E 3 13  ? 153.917 134.651 131.334 1.00 224.94 ?  13  DC  A OP1   1 
ATOM 7742 O OP2   . DC  E 3 13  ? 152.279 133.507 132.931 1.00 224.94 -1 13  DC  A OP2   1 
ATOM 7743 O "O5'" . DC  E 3 13  ? 151.885 135.848 132.171 1.00 224.94 ?  13  DC  A "O5'" 1 
ATOM 7744 C "C5'" . DC  E 3 13  ? 151.887 136.899 131.210 1.00 224.94 ?  13  DC  A "C5'" 1 
ATOM 7745 C "C4'" . DC  E 3 13  ? 151.403 138.198 131.829 1.00 224.94 ?  13  DC  A "C4'" 1 
ATOM 7746 O "O4'" . DC  E 3 13  ? 149.961 138.154 131.985 1.00 224.94 ?  13  DC  A "O4'" 1 
ATOM 7747 C "C3'" . DC  E 3 13  ? 151.980 138.504 133.211 1.00 224.94 ?  13  DC  A "C3'" 1 
ATOM 7748 O "O3'" . DC  E 3 13  ? 152.377 139.865 133.292 1.00 224.94 ?  13  DC  A "O3'" 1 
ATOM 7749 C "C2'" . DC  E 3 13  ? 150.825 138.198 134.160 1.00 224.94 ?  13  DC  A "C2'" 1 
ATOM 7750 C "C1'" . DC  E 3 13  ? 149.610 138.506 133.303 1.00 224.94 ?  13  DC  A "C1'" 1 
ATOM 7751 N N1    . DC  E 3 13  ? 148.413 137.716 133.690 1.00 224.94 ?  13  DC  A N1    1 
ATOM 7752 C C2    . DC  E 3 13  ? 147.223 138.371 134.024 1.00 224.94 ?  13  DC  A C2    1 
ATOM 7753 O O2    . DC  E 3 13  ? 147.183 139.607 133.986 1.00 224.94 ?  13  DC  A O2    1 
ATOM 7754 N N3    . DC  E 3 13  ? 146.144 137.630 134.374 1.00 224.94 ?  13  DC  A N3    1 
ATOM 7755 C C4    . DC  E 3 13  ? 146.229 136.298 134.400 1.00 224.94 ?  13  DC  A C4    1 
ATOM 7756 N N4    . DC  E 3 13  ? 145.141 135.608 134.752 1.00 224.94 ?  13  DC  A N4    1 
ATOM 7757 C C5    . DC  E 3 13  ? 147.435 135.615 134.069 1.00 224.94 ?  13  DC  A C5    1 
ATOM 7758 C C6    . DC  E 3 13  ? 148.490 136.356 133.722 1.00 224.94 ?  13  DC  A C6    1 
ATOM 7759 P P     . DT  E 3 14  ? 153.287 140.364 134.518 1.00 225.53 ?  14  DT  A P     1 
ATOM 7760 O OP1   . DT  E 3 14  ? 154.292 141.305 133.977 1.00 225.53 ?  14  DT  A OP1   1 
ATOM 7761 O OP2   . DT  E 3 14  ? 153.729 139.167 135.269 1.00 225.53 -1 14  DT  A OP2   1 
ATOM 7762 O "O5'" . DT  E 3 14  ? 152.270 141.174 135.447 1.00 225.53 ?  14  DT  A "O5'" 1 
ATOM 7763 C "C5'" . DT  E 3 14  ? 151.614 142.326 134.936 1.00 225.53 ?  14  DT  A "C5'" 1 
ATOM 7764 C "C4'" . DT  E 3 14  ? 150.631 142.888 135.948 1.00 225.53 ?  14  DT  A "C4'" 1 
ATOM 7765 O "O4'" . DT  E 3 14  ? 149.563 141.932 136.177 1.00 225.53 ?  14  DT  A "O4'" 1 
ATOM 7766 C "C3'" . DT  E 3 14  ? 151.220 143.210 137.320 1.00 225.53 ?  14  DT  A "C3'" 1 
ATOM 7767 O "O3'" . DT  E 3 14  ? 150.690 144.444 137.784 1.00 225.53 ?  14  DT  A "O3'" 1 
ATOM 7768 C "C2'" . DT  E 3 14  ? 150.763 142.033 138.183 1.00 225.53 ?  14  DT  A "C2'" 1 
ATOM 7769 C "C1'" . DT  E 3 14  ? 149.419 141.698 137.560 1.00 225.53 ?  14  DT  A "C1'" 1 
ATOM 7770 N N1    . DT  E 3 14  ? 149.014 140.279 137.746 1.00 225.53 ?  14  DT  A N1    1 
ATOM 7771 C C2    . DT  E 3 14  ? 147.729 139.993 138.140 1.00 225.53 ?  14  DT  A C2    1 
ATOM 7772 O O2    . DT  E 3 14  ? 146.890 140.849 138.359 1.00 225.53 ?  14  DT  A O2    1 
ATOM 7773 N N3    . DT  E 3 14  ? 147.456 138.659 138.274 1.00 225.53 ?  14  DT  A N3    1 
ATOM 7774 C C4    . DT  E 3 14  ? 148.322 137.604 138.054 1.00 225.53 ?  14  DT  A C4    1 
ATOM 7775 O O4    . DT  E 3 14  ? 147.982 136.436 138.202 1.00 225.53 ?  14  DT  A O4    1 
ATOM 7776 C C5    . DT  E 3 14  ? 149.653 137.972 137.641 1.00 225.53 ?  14  DT  A C5    1 
ATOM 7777 C C7    . DT  E 3 14  ? 150.678 136.909 137.378 1.00 225.53 ?  14  DT  A C7    1 
ATOM 7778 C C6    . DT  E 3 14  ? 149.932 139.277 137.506 1.00 225.53 ?  14  DT  A C6    1 
ATOM 7779 P P     . DC  E 3 15  ? 151.191 145.088 139.168 1.00 224.65 ?  15  DC  A P     1 
ATOM 7780 O OP1   . DC  E 3 15  ? 151.400 146.533 138.929 1.00 224.65 ?  15  DC  A OP1   1 
ATOM 7781 O OP2   . DC  E 3 15  ? 152.303 144.271 139.703 1.00 224.65 -1 15  DC  A OP2   1 
ATOM 7782 O "O5'" . DC  E 3 15  ? 149.932 144.914 140.134 1.00 224.65 ?  15  DC  A "O5'" 1 
ATOM 7783 C "C5'" . DC  E 3 15  ? 148.644 145.333 139.695 1.00 224.65 ?  15  DC  A "C5'" 1 
ATOM 7784 C "C4'" . DC  E 3 15  ? 147.576 144.927 140.690 1.00 224.65 ?  15  DC  A "C4'" 1 
ATOM 7785 O "O4'" . DC  E 3 15  ? 147.279 143.511 140.540 1.00 224.65 ?  15  DC  A "O4'" 1 
ATOM 7786 C "C3'" . DC  E 3 15  ? 147.956 145.126 142.158 1.00 224.65 ?  15  DC  A "C3'" 1 
ATOM 7787 O "O3'" . DC  E 3 15  ? 146.840 145.614 142.885 1.00 224.65 ?  15  DC  A "O3'" 1 
ATOM 7788 C "C2'" . DC  E 3 15  ? 148.335 143.717 142.603 1.00 224.65 ?  15  DC  A "C2'" 1 
ATOM 7789 C "C1'" . DC  E 3 15  ? 147.345 142.890 141.802 1.00 224.65 ?  15  DC  A "C1'" 1 
ATOM 7790 N N1    . DC  E 3 15  ? 147.762 141.474 141.619 1.00 224.65 ?  15  DC  A N1    1 
ATOM 7791 C C2    . DC  E 3 15  ? 146.851 140.445 141.882 1.00 224.65 ?  15  DC  A C2    1 
ATOM 7792 O O2    . DC  E 3 15  ? 145.707 140.731 142.256 1.00 224.65 ?  15  DC  A O2    1 
ATOM 7793 N N3    . DC  E 3 15  ? 147.249 139.160 141.714 1.00 224.65 ?  15  DC  A N3    1 
ATOM 7794 C C4    . DC  E 3 15  ? 148.491 138.894 141.308 1.00 224.65 ?  15  DC  A C4    1 
ATOM 7795 N N4    . DC  E 3 15  ? 148.838 137.612 141.157 1.00 224.65 ?  15  DC  A N4    1 
ATOM 7796 C C5    . DC  E 3 15  ? 149.433 139.929 141.040 1.00 224.65 ?  15  DC  A C5    1 
ATOM 7797 C C6    . DC  E 3 15  ? 149.030 141.192 141.208 1.00 224.65 ?  15  DC  A C6    1 
ATOM 7798 P P     . DG  E 3 16  ? 147.054 146.640 144.102 1.00 224.36 ?  16  DG  A P     1 
ATOM 7799 O OP1   . DG  E 3 16  ? 147.154 148.001 143.531 1.00 224.36 ?  16  DG  A OP1   1 
ATOM 7800 O OP2   . DG  E 3 16  ? 148.147 146.112 144.948 1.00 224.36 -1 16  DG  A OP2   1 
ATOM 7801 O "O5'" . DG  E 3 16  ? 145.694 146.527 144.935 1.00 224.36 ?  16  DG  A "O5'" 1 
ATOM 7802 C "C5'" . DG  E 3 16  ? 144.444 146.615 144.265 1.00 224.36 ?  16  DG  A "C5'" 1 
ATOM 7803 C "C4'" . DG  E 3 16  ? 143.502 145.526 144.742 1.00 224.36 ?  16  DG  A "C4'" 1 
ATOM 7804 O "O4'" . DG  E 3 16  ? 144.026 144.229 144.351 1.00 224.36 ?  16  DG  A "O4'" 1 
ATOM 7805 C "C3'" . DG  E 3 16  ? 143.299 145.472 146.258 1.00 224.36 ?  16  DG  A "C3'" 1 
ATOM 7806 O "O3'" . DG  E 3 16  ? 141.917 145.356 146.566 1.00 224.36 ?  16  DG  A "O3'" 1 
ATOM 7807 C "C2'" . DG  E 3 16  ? 144.078 144.230 146.687 1.00 224.36 ?  16  DG  A "C2'" 1 
ATOM 7808 C "C1'" . DG  E 3 16  ? 143.988 143.351 145.450 1.00 224.36 ?  16  DG  A "C1'" 1 
ATOM 7809 N N9    . DG  E 3 16  ? 145.104 142.418 145.336 1.00 224.36 ?  16  DG  A N9    1 
ATOM 7810 C C8    . DG  E 3 16  ? 146.420 142.734 145.113 1.00 224.36 ?  16  DG  A C8    1 
ATOM 7811 N N7    . DG  E 3 16  ? 147.206 141.696 145.067 1.00 224.36 ?  16  DG  A N7    1 
ATOM 7812 C C5    . DG  E 3 16  ? 146.358 140.619 145.284 1.00 224.36 ?  16  DG  A C5    1 
ATOM 7813 C C6    . DG  E 3 16  ? 146.642 139.236 145.345 1.00 224.36 ?  16  DG  A C6    1 
ATOM 7814 O O6    . DG  E 3 16  ? 147.737 138.670 145.218 1.00 224.36 ?  16  DG  A O6    1 
ATOM 7815 N N1    . DG  E 3 16  ? 145.495 138.485 145.585 1.00 224.36 ?  16  DG  A N1    1 
ATOM 7816 C C2    . DG  E 3 16  ? 144.233 139.006 145.744 1.00 224.36 ?  16  DG  A C2    1 
ATOM 7817 N N2    . DG  E 3 16  ? 143.249 138.123 145.965 1.00 224.36 ?  16  DG  A N2    1 
ATOM 7818 N N3    . DG  E 3 16  ? 143.952 140.302 145.685 1.00 224.36 ?  16  DG  A N3    1 
ATOM 7819 C C4    . DG  E 3 16  ? 145.059 141.046 145.449 1.00 224.36 ?  16  DG  A C4    1 
ATOM 7820 P P     . DA  E 3 17  ? 141.422 145.447 148.093 1.00 221.15 ?  17  DA  A P     1 
ATOM 7821 O OP1   . DA  E 3 17  ? 140.101 146.113 148.095 1.00 221.15 ?  17  DA  A OP1   1 
ATOM 7822 O OP2   . DA  E 3 17  ? 142.529 146.009 148.897 1.00 221.15 -1 17  DA  A OP2   1 
ATOM 7823 O "O5'" . DA  E 3 17  ? 141.229 143.919 148.524 1.00 221.15 ?  17  DA  A "O5'" 1 
ATOM 7824 C "C5'" . DA  E 3 17  ? 140.295 143.101 147.831 1.00 221.15 ?  17  DA  A "C5'" 1 
ATOM 7825 C "C4'" . DA  E 3 17  ? 140.353 141.666 148.326 1.00 221.15 ?  17  DA  A "C4'" 1 
ATOM 7826 O "O4'" . DA  E 3 17  ? 141.595 141.048 147.895 1.00 221.15 ?  17  DA  A "O4'" 1 
ATOM 7827 C "C3'" . DA  E 3 17  ? 140.299 141.499 149.847 1.00 221.15 ?  17  DA  A "C3'" 1 
ATOM 7828 O "O3'" . DA  E 3 17  ? 139.419 140.433 150.181 1.00 221.15 ?  17  DA  A "O3'" 1 
ATOM 7829 C "C2'" . DA  E 3 17  ? 141.745 141.166 150.212 1.00 221.15 ?  17  DA  A "C2'" 1 
ATOM 7830 C "C1'" . DA  E 3 17  ? 142.181 140.382 148.987 1.00 221.15 ?  17  DA  A "C1'" 1 
ATOM 7831 N N9    . DA  E 3 17  ? 143.627 140.348 148.791 1.00 221.15 ?  17  DA  A N9    1 
ATOM 7832 C C8    . DA  E 3 17  ? 144.450 141.408 148.534 1.00 221.15 ?  17  DA  A C8    1 
ATOM 7833 N N7    . DA  E 3 17  ? 145.712 141.078 148.397 1.00 221.15 ?  17  DA  A N7    1 
ATOM 7834 C C5    . DA  E 3 17  ? 145.717 139.705 148.577 1.00 221.15 ?  17  DA  A C5    1 
ATOM 7835 C C6    . DA  E 3 17  ? 146.751 138.748 148.557 1.00 221.15 ?  17  DA  A C6    1 
ATOM 7836 N N6    . DA  E 3 17  ? 148.032 139.055 148.334 1.00 221.15 ?  17  DA  A N6    1 
ATOM 7837 N N1    . DA  E 3 17  ? 146.415 137.460 148.775 1.00 221.15 ?  17  DA  A N1    1 
ATOM 7838 C C2    . DA  E 3 17  ? 145.131 137.157 148.993 1.00 221.15 ?  17  DA  A C2    1 
ATOM 7839 N N3    . DA  E 3 17  ? 144.075 137.968 149.041 1.00 221.15 ?  17  DA  A N3    1 
ATOM 7840 C C4    . DA  E 3 17  ? 144.440 139.240 148.821 1.00 221.15 ?  17  DA  A C4    1 
ATOM 7841 P P     . DG  E 3 18  ? 138.781 140.335 151.652 1.00 206.07 ?  18  DG  A P     1 
ATOM 7842 O OP1   . DG  E 3 18  ? 137.694 139.333 151.606 1.00 206.07 ?  18  DG  A OP1   1 
ATOM 7843 O OP2   . DG  E 3 18  ? 138.492 141.714 152.106 1.00 206.07 -1 18  DG  A OP2   1 
ATOM 7844 O "O5'" . DG  E 3 18  ? 139.974 139.764 152.551 1.00 206.07 ?  18  DG  A "O5'" 1 
ATOM 7845 C "C5'" . DG  E 3 18  ? 139.697 138.870 153.621 1.00 206.07 ?  18  DG  A "C5'" 1 
ATOM 7846 C "C4'" . DG  E 3 18  ? 139.876 137.431 153.177 1.00 206.07 ?  18  DG  A "C4'" 1 
ATOM 7847 O "O4'" . DG  E 3 18  ? 140.942 137.363 152.195 1.00 206.07 ?  18  DG  A "O4'" 1 
ATOM 7848 C "C3'" . DG  E 3 18  ? 140.297 136.470 154.278 1.00 206.07 ?  18  DG  A "C3'" 1 
ATOM 7849 O "O3'" . DG  E 3 18  ? 139.924 135.144 153.925 1.00 206.07 ?  18  DG  A "O3'" 1 
ATOM 7850 C "C2'" . DG  E 3 18  ? 141.808 136.639 154.259 1.00 206.07 ?  18  DG  A "C2'" 1 
ATOM 7851 C "C1'" . DG  E 3 18  ? 142.065 136.710 152.759 1.00 206.07 ?  18  DG  A "C1'" 1 
ATOM 7852 N N9    . DG  E 3 18  ? 143.262 137.461 152.404 1.00 206.07 ?  18  DG  A N9    1 
ATOM 7853 C C8    . DG  E 3 18  ? 143.334 138.788 152.066 1.00 206.07 ?  18  DG  A C8    1 
ATOM 7854 N N7    . DG  E 3 18  ? 144.543 139.189 151.793 1.00 206.07 ?  18  DG  A N7    1 
ATOM 7855 C C5    . DG  E 3 18  ? 145.323 138.054 151.961 1.00 206.07 ?  18  DG  A C5    1 
ATOM 7856 C C6    . DG  E 3 18  ? 146.716 137.873 151.796 1.00 206.07 ?  18  DG  A C6    1 
ATOM 7857 O O6    . DG  E 3 18  ? 147.565 138.711 151.463 1.00 206.07 ?  18  DG  A O6    1 
ATOM 7858 N N1    . DG  E 3 18  ? 147.099 136.561 152.057 1.00 206.07 ?  18  DG  A N1    1 
ATOM 7859 C C2    . DG  E 3 18  ? 146.244 135.552 152.424 1.00 206.07 ?  18  DG  A C2    1 
ATOM 7860 N N2    . DG  E 3 18  ? 146.802 134.353 152.646 1.00 206.07 ?  18  DG  A N2    1 
ATOM 7861 N N3    . DG  E 3 18  ? 144.937 135.708 152.585 1.00 206.07 ?  18  DG  A N3    1 
ATOM 7862 C C4    . DG  E 3 18  ? 144.548 136.980 152.331 1.00 206.07 ?  18  DG  A C4    1 
ATOM 7863 P P     . DA  E 3 19  ? 139.534 134.079 155.062 1.00 196.84 ?  19  DA  A P     1 
ATOM 7864 O OP1   . DA  E 3 19  ? 139.030 132.865 154.383 1.00 196.84 ?  19  DA  A OP1   1 
ATOM 7865 O OP2   . DA  E 3 19  ? 138.683 134.774 156.053 1.00 196.84 -1 19  DA  A OP2   1 
ATOM 7866 O "O5'" . DA  E 3 19  ? 140.928 133.733 155.767 1.00 196.84 ?  19  DA  A "O5'" 1 
ATOM 7867 C "C5'" . DA  E 3 19  ? 142.002 133.197 155.001 1.00 196.84 ?  19  DA  A "C5'" 1 
ATOM 7868 C "C4'" . DA  E 3 19  ? 142.933 132.382 155.878 1.00 196.84 ?  19  DA  A "C4'" 1 
ATOM 7869 O "O4'" . DA  E 3 19  ? 144.309 132.738 155.591 1.00 196.84 ?  19  DA  A "O4'" 1 
ATOM 7870 C "C3'" . DA  E 3 19  ? 142.774 132.608 157.369 1.00 196.84 ?  19  DA  A "C3'" 1 
ATOM 7871 O "O3'" . DA  E 3 19  ? 143.216 131.449 158.068 1.00 196.84 ?  19  DA  A "O3'" 1 
ATOM 7872 C "C2'" . DA  E 3 19  ? 143.693 133.803 157.606 1.00 196.84 ?  19  DA  A "C2'" 1 
ATOM 7873 C "C1'" . DA  E 3 19  ? 144.852 133.488 156.667 1.00 196.84 ?  19  DA  A "C1'" 1 
ATOM 7874 N N9    . DA  E 3 19  ? 145.496 134.669 156.107 1.00 196.84 ?  19  DA  A N9    1 
ATOM 7875 C C8    . DA  E 3 19  ? 144.892 135.828 155.708 1.00 196.84 ?  19  DA  A C8    1 
ATOM 7876 N N7    . DA  E 3 19  ? 145.724 136.718 155.224 1.00 196.84 ?  19  DA  A N7    1 
ATOM 7877 C C5    . DA  E 3 19  ? 146.959 136.095 155.302 1.00 196.84 ?  19  DA  A C5    1 
ATOM 7878 C C6    . DA  E 3 19  ? 148.256 136.508 154.936 1.00 196.84 ?  19  DA  A C6    1 
ATOM 7879 N N6    . DA  E 3 19  ? 148.525 137.704 154.403 1.00 196.84 ?  19  DA  A N6    1 
ATOM 7880 N N1    . DA  E 3 19  ? 149.269 135.642 155.143 1.00 196.84 ?  19  DA  A N1    1 
ATOM 7881 C C2    . DA  E 3 19  ? 148.995 134.445 155.676 1.00 196.84 ?  19  DA  A C2    1 
ATOM 7882 N N3    . DA  E 3 19  ? 147.820 133.946 156.056 1.00 196.84 ?  19  DA  A N3    1 
ATOM 7883 C C4    . DA  E 3 19  ? 146.834 134.829 155.837 1.00 196.84 ?  19  DA  A C4    1 
ATOM 7884 P P     . DT  E 3 20  ? 143.450 131.480 159.657 1.00 198.43 ?  20  DT  A P     1 
ATOM 7885 O OP1   . DT  E 3 20  ? 143.260 130.097 160.145 1.00 198.43 ?  20  DT  A OP1   1 
ATOM 7886 O OP2   . DT  E 3 20  ? 142.642 132.573 160.241 1.00 198.43 -1 20  DT  A OP2   1 
ATOM 7887 O "O5'" . DT  E 3 20  ? 144.996 131.855 159.801 1.00 198.43 ?  20  DT  A "O5'" 1 
ATOM 7888 C "C5'" . DT  E 3 20  ? 145.974 131.100 159.094 1.00 198.43 ?  20  DT  A "C5'" 1 
ATOM 7889 C "C4'" . DT  E 3 20  ? 147.303 131.103 159.829 1.00 198.43 ?  20  DT  A "C4'" 1 
ATOM 7890 O "O4'" . DT  E 3 20  ? 148.169 132.125 159.277 1.00 198.43 ?  20  DT  A "O4'" 1 
ATOM 7891 C "C3'" . DT  E 3 20  ? 147.219 131.387 161.318 1.00 198.43 ?  20  DT  A "C3'" 1 
ATOM 7892 O "O3'" . DT  E 3 20  ? 148.232 130.663 161.996 1.00 198.43 ?  20  DT  A "O3'" 1 
ATOM 7893 C "C2'" . DT  E 3 20  ? 147.447 132.897 161.394 1.00 198.43 ?  20  DT  A "C2'" 1 
ATOM 7894 C "C1'" . DT  E 3 20  ? 148.407 133.141 160.234 1.00 198.43 ?  20  DT  A "C1'" 1 
ATOM 7895 N N1    . DT  E 3 20  ? 148.204 134.450 159.558 1.00 198.43 ?  20  DT  A N1    1 
ATOM 7896 C C2    . DT  E 3 20  ? 149.274 135.068 158.957 1.00 198.43 ?  20  DT  A C2    1 
ATOM 7897 O O2    . DT  E 3 20  ? 150.400 134.604 158.958 1.00 198.43 ?  20  DT  A O2    1 
ATOM 7898 N N3    . DT  E 3 20  ? 148.981 136.259 158.351 1.00 198.43 ?  20  DT  A N3    1 
ATOM 7899 C C4    . DT  E 3 20  ? 147.748 136.881 158.286 1.00 198.43 ?  20  DT  A C4    1 
ATOM 7900 O O4    . DT  E 3 20  ? 147.584 137.954 157.715 1.00 198.43 ?  20  DT  A O4    1 
ATOM 7901 C C5    . DT  E 3 20  ? 146.667 136.176 158.931 1.00 198.43 ?  20  DT  A C5    1 
ATOM 7902 C C7    . DT  E 3 20  ? 145.283 136.754 158.928 1.00 198.43 ?  20  DT  A C7    1 
ATOM 7903 C C6    . DT  E 3 20  ? 146.943 135.007 159.527 1.00 198.43 ?  20  DT  A C6    1 
ATOM 7904 P P     . DC  E 3 21  ? 148.409 130.805 163.585 1.00 204.63 ?  21  DC  A P     1 
ATOM 7905 O OP1   . DC  E 3 21  ? 149.014 129.550 164.080 1.00 204.63 ?  21  DC  A OP1   1 
ATOM 7906 O OP2   . DC  E 3 21  ? 147.127 131.281 164.151 1.00 204.63 -1 21  DC  A OP2   1 
ATOM 7907 O "O5'" . DC  E 3 21  ? 149.479 131.976 163.733 1.00 204.63 ?  21  DC  A "O5'" 1 
ATOM 7908 C "C5'" . DC  E 3 21  ? 150.627 131.985 162.901 1.00 204.63 ?  21  DC  A "C5'" 1 
ATOM 7909 C "C4'" . DC  E 3 21  ? 151.505 133.173 163.226 1.00 204.63 ?  21  DC  A "C4'" 1 
ATOM 7910 O "O4'" . DC  E 3 21  ? 151.058 134.334 162.480 1.00 204.63 ?  21  DC  A "O4'" 1 
ATOM 7911 C "C3'" . DC  E 3 21  ? 151.497 133.582 164.701 1.00 204.63 ?  21  DC  A "C3'" 1 
ATOM 7912 O "O3'" . DC  E 3 21  ? 152.823 133.769 165.155 1.00 204.63 ?  21  DC  A "O3'" 1 
ATOM 7913 C "C2'" . DC  E 3 21  ? 150.713 134.895 164.702 1.00 204.63 ?  21  DC  A "C2'" 1 
ATOM 7914 C "C1'" . DC  E 3 21  ? 151.067 135.449 163.334 1.00 204.63 ?  21  DC  A "C1'" 1 
ATOM 7915 N N1    . DC  E 3 21  ? 150.097 136.458 162.823 1.00 204.63 ?  21  DC  A N1    1 
ATOM 7916 C C2    . DC  E 3 21  ? 150.549 137.499 162.006 1.00 204.63 ?  21  DC  A C2    1 
ATOM 7917 O O2    . DC  E 3 21  ? 151.750 137.559 161.717 1.00 204.63 ?  21  DC  A O2    1 
ATOM 7918 N N3    . DC  E 3 21  ? 149.657 138.412 161.552 1.00 204.63 ?  21  DC  A N3    1 
ATOM 7919 C C4    . DC  E 3 21  ? 148.370 138.312 161.888 1.00 204.63 ?  21  DC  A C4    1 
ATOM 7920 N N4    . DC  E 3 21  ? 147.528 139.236 161.416 1.00 204.63 ?  21  DC  A N4    1 
ATOM 7921 C C5    . DC  E 3 21  ? 147.891 137.260 162.723 1.00 204.63 ?  21  DC  A C5    1 
ATOM 7922 C C6    . DC  E 3 21  ? 148.780 136.365 163.164 1.00 204.63 ?  21  DC  A C6    1 
ATOM 7923 P P     . DA  E 3 22  ? 153.266 133.230 166.601 1.00 225.10 ?  22  DA  A P     1 
ATOM 7924 O OP1   . DA  E 3 22  ? 153.502 131.774 166.484 1.00 225.10 ?  22  DA  A OP1   1 
ATOM 7925 O OP2   . DA  E 3 22  ? 152.288 133.740 167.587 1.00 225.10 -1 22  DA  A OP2   1 
ATOM 7926 O "O5'" . DA  E 3 22  ? 154.661 133.963 166.861 1.00 225.10 ?  22  DA  A "O5'" 1 
ATOM 7927 C "C5'" . DA  E 3 22  ? 154.873 135.272 166.348 1.00 225.10 ?  22  DA  A "C5'" 1 
ATOM 7928 C "C4'" . DA  E 3 22  ? 155.217 136.239 167.463 1.00 225.10 ?  22  DA  A "C4'" 1 
ATOM 7929 O "O4'" . DA  E 3 22  ? 154.911 137.589 167.035 1.00 225.10 ?  22  DA  A "O4'" 1 
ATOM 7930 C "C3'" . DA  E 3 22  ? 154.423 136.047 168.741 1.00 225.10 ?  22  DA  A "C3'" 1 
ATOM 7931 O "O3'" . DA  E 3 22  ? 155.144 136.585 169.840 1.00 225.10 ?  22  DA  A "O3'" 1 
ATOM 7932 C "C2'" . DA  E 3 22  ? 153.162 136.852 168.451 1.00 225.10 ?  22  DA  A "C2'" 1 
ATOM 7933 C "C1'" . DA  E 3 22  ? 153.719 138.036 167.661 1.00 225.10 ?  22  DA  A "C1'" 1 
ATOM 7934 N N9    . DA  E 3 22  ? 152.812 138.520 166.624 1.00 225.10 ?  22  DA  A N9    1 
ATOM 7935 C C8    . DA  E 3 22  ? 152.043 137.763 165.788 1.00 225.10 ?  22  DA  A C8    1 
ATOM 7936 N N7    . DA  E 3 22  ? 151.322 138.466 164.947 1.00 225.10 ?  22  DA  A N7    1 
ATOM 7937 C C5    . DA  E 3 22  ? 151.643 139.777 165.252 1.00 225.10 ?  22  DA  A C5    1 
ATOM 7938 C C6    . DA  E 3 22  ? 151.214 141.007 164.716 1.00 225.10 ?  22  DA  A C6    1 
ATOM 7939 N N6    . DA  E 3 22  ? 150.331 141.107 163.718 1.00 225.10 ?  22  DA  A N6    1 
ATOM 7940 N N1    . DA  E 3 22  ? 151.730 142.134 165.249 1.00 225.10 ?  22  DA  A N1    1 
ATOM 7941 C C2    . DA  E 3 22  ? 152.613 142.029 166.248 1.00 225.10 ?  22  DA  A C2    1 
ATOM 7942 N N3    . DA  E 3 22  ? 153.091 140.932 166.834 1.00 225.10 ?  22  DA  A N3    1 
ATOM 7943 C C4    . DA  E 3 22  ? 152.561 139.829 166.283 1.00 225.10 ?  22  DA  A C4    1 
ATOM 7944 P P     . DG  E 3 23  ? 154.769 136.161 171.344 1.00 243.02 ?  23  DG  A P     1 
ATOM 7945 O OP1   . DG  E 3 23  ? 155.995 135.623 171.974 1.00 243.02 ?  23  DG  A OP1   1 
ATOM 7946 O OP2   . DG  E 3 23  ? 153.546 135.329 171.291 1.00 243.02 -1 23  DG  A OP2   1 
ATOM 7947 O "O5'" . DG  E 3 23  ? 154.394 137.547 172.047 1.00 243.02 ?  23  DG  A "O5'" 1 
ATOM 7948 C "C5'" . DG  E 3 23  ? 155.357 138.594 172.107 1.00 243.02 ?  23  DG  A "C5'" 1 
ATOM 7949 C "C4'" . DG  E 3 23  ? 154.685 139.939 172.319 1.00 243.02 ?  23  DG  A "C4'" 1 
ATOM 7950 O "O4'" . DG  E 3 23  ? 153.920 140.294 171.137 1.00 243.02 ?  23  DG  A "O4'" 1 
ATOM 7951 C "C3'" . DG  E 3 23  ? 153.708 139.998 173.497 1.00 243.02 ?  23  DG  A "C3'" 1 
ATOM 7952 O "O3'" . DG  E 3 23  ? 153.931 141.180 174.255 1.00 243.02 ?  23  DG  A "O3'" 1 
ATOM 7953 C "C2'" . DG  E 3 23  ? 152.336 140.013 172.823 1.00 243.02 ?  23  DG  A "C2'" 1 
ATOM 7954 C "C1'" . DG  E 3 23  ? 152.642 140.738 171.523 1.00 243.02 ?  23  DG  A "C1'" 1 
ATOM 7955 N N9    . DG  E 3 23  ? 151.700 140.433 170.449 1.00 243.02 ?  23  DG  A N9    1 
ATOM 7956 C C8    . DG  E 3 23  ? 151.282 139.189 170.044 1.00 243.02 ?  23  DG  A C8    1 
ATOM 7957 N N7    . DG  E 3 23  ? 150.434 139.222 169.053 1.00 243.02 ?  23  DG  A N7    1 
ATOM 7958 C C5    . DG  E 3 23  ? 150.279 140.576 168.784 1.00 243.02 ?  23  DG  A C5    1 
ATOM 7959 C C6    . DG  E 3 23  ? 149.481 141.227 167.813 1.00 243.02 ?  23  DG  A C6    1 
ATOM 7960 O O6    . DG  E 3 23  ? 148.728 140.717 166.971 1.00 243.02 ?  23  DG  A O6    1 
ATOM 7961 N N1    . DG  E 3 23  ? 149.615 142.611 167.880 1.00 243.02 ?  23  DG  A N1    1 
ATOM 7962 C C2    . DG  E 3 23  ? 150.419 143.282 168.772 1.00 243.02 ?  23  DG  A C2    1 
ATOM 7963 N N2    . DG  E 3 23  ? 150.417 144.620 168.683 1.00 243.02 ?  23  DG  A N2    1 
ATOM 7964 N N3    . DG  E 3 23  ? 151.171 142.684 169.687 1.00 243.02 ?  23  DG  A N3    1 
ATOM 7965 C C4    . DG  E 3 23  ? 151.052 141.335 169.635 1.00 243.02 ?  23  DG  A C4    1 
ATOM 7966 P P     . DA  F 4 1   ? 159.761 143.509 159.259 1.00 225.62 ?  21  DA  F P     1 
ATOM 7967 O OP1   . DA  F 4 1   ? 159.752 143.850 160.699 1.00 225.62 ?  21  DA  F OP1   1 
ATOM 7968 O OP2   . DA  F 4 1   ? 160.971 143.768 158.446 1.00 225.62 -1 21  DA  F OP2   1 
ATOM 7969 O "O5'" . DA  F 4 1   ? 159.373 141.966 159.089 1.00 225.62 ?  21  DA  F "O5'" 1 
ATOM 7970 C "C5'" . DA  F 4 1   ? 159.835 141.010 160.034 1.00 225.62 ?  21  DA  F "C5'" 1 
ATOM 7971 C "C4'" . DA  F 4 1   ? 159.369 139.614 159.661 1.00 225.62 ?  21  DA  F "C4'" 1 
ATOM 7972 O "O4'" . DA  F 4 1   ? 157.961 139.470 159.972 1.00 225.62 ?  21  DA  F "O4'" 1 
ATOM 7973 C "C3'" . DA  F 4 1   ? 159.525 139.256 158.180 1.00 225.62 ?  21  DA  F "C3'" 1 
ATOM 7974 O "O3'" . DA  F 4 1   ? 160.216 138.021 158.048 1.00 225.62 ?  21  DA  F "O3'" 1 
ATOM 7975 C "C2'" . DA  F 4 1   ? 158.084 139.157 157.668 1.00 225.62 ?  21  DA  F "C2'" 1 
ATOM 7976 C "C1'" . DA  F 4 1   ? 157.325 138.778 158.928 1.00 225.62 ?  21  DA  F "C1'" 1 
ATOM 7977 N N9    . DA  F 4 1   ? 155.920 139.173 158.901 1.00 225.62 ?  21  DA  F N9    1 
ATOM 7978 C C8    . DA  F 4 1   ? 155.423 140.446 158.876 1.00 225.62 ?  21  DA  F C8    1 
ATOM 7979 N N7    . DA  F 4 1   ? 154.112 140.503 158.855 1.00 225.62 ?  21  DA  F N7    1 
ATOM 7980 C C5    . DA  F 4 1   ? 153.722 139.174 158.868 1.00 225.62 ?  21  DA  F C5    1 
ATOM 7981 C C6    . DA  F 4 1   ? 152.455 138.557 158.855 1.00 225.62 ?  21  DA  F C6    1 
ATOM 7982 N N6    . DA  F 4 1   ? 151.305 139.237 158.828 1.00 225.62 ?  21  DA  F N6    1 
ATOM 7983 N N1    . DA  F 4 1   ? 152.418 137.208 158.873 1.00 225.62 ?  21  DA  F N1    1 
ATOM 7984 C C2    . DA  F 4 1   ? 153.571 136.531 158.900 1.00 225.62 ?  21  DA  F C2    1 
ATOM 7985 N N3    . DA  F 4 1   ? 154.818 136.999 158.913 1.00 225.62 ?  21  DA  F N3    1 
ATOM 7986 C C4    . DA  F 4 1   ? 154.824 138.341 158.895 1.00 225.62 ?  21  DA  F C4    1 
ATOM 7987 P P     . DT  F 4 2   ? 160.606 137.464 156.592 1.00 230.35 ?  22  DT  F P     1 
ATOM 7988 O OP1   . DT  F 4 2   ? 161.813 136.621 156.743 1.00 230.35 ?  22  DT  F OP1   1 
ATOM 7989 O OP2   . DT  F 4 2   ? 160.623 138.612 155.658 1.00 230.35 -1 22  DT  F OP2   1 
ATOM 7990 O "O5'" . DT  F 4 2   ? 159.369 136.529 156.201 1.00 230.35 ?  22  DT  F "O5'" 1 
ATOM 7991 C "C5'" . DT  F 4 2   ? 158.945 135.508 157.095 1.00 230.35 ?  22  DT  F "C5'" 1 
ATOM 7992 C "C4'" . DT  F 4 2   ? 157.900 134.620 156.445 1.00 230.35 ?  22  DT  F "C4'" 1 
ATOM 7993 O "O4'" . DT  F 4 2   ? 156.581 135.161 156.679 1.00 230.35 ?  22  DT  F "O4'" 1 
ATOM 7994 C "C3'" . DT  F 4 2   ? 158.036 134.465 154.926 1.00 230.35 ?  22  DT  F "C3'" 1 
ATOM 7995 O "O3'" . DT  F 4 2   ? 158.267 133.102 154.597 1.00 230.35 ?  22  DT  F "O3'" 1 
ATOM 7996 C "C2'" . DT  F 4 2   ? 156.693 134.966 154.370 1.00 230.35 ?  22  DT  F "C2'" 1 
ATOM 7997 C "C1'" . DT  F 4 2   ? 155.776 134.849 155.576 1.00 230.35 ?  22  DT  F "C1'" 1 
ATOM 7998 N N1    . DT  F 4 2   ? 154.625 135.794 155.542 1.00 230.35 ?  22  DT  F N1    1 
ATOM 7999 C C2    . DT  F 4 2   ? 153.344 135.294 155.535 1.00 230.35 ?  22  DT  F C2    1 
ATOM 8000 O O2    . DT  F 4 2   ? 153.092 134.103 155.557 1.00 230.35 ?  22  DT  F O2    1 
ATOM 8001 N N3    . DT  F 4 2   ? 152.359 136.244 155.499 1.00 230.35 ?  22  DT  F N3    1 
ATOM 8002 C C4    . DT  F 4 2   ? 152.523 137.616 155.471 1.00 230.35 ?  22  DT  F C4    1 
ATOM 8003 O O4    . DT  F 4 2   ? 151.572 138.390 155.440 1.00 230.35 ?  22  DT  F O4    1 
ATOM 8004 C C5    . DT  F 4 2   ? 153.893 138.074 155.479 1.00 230.35 ?  22  DT  F C5    1 
ATOM 8005 C C7    . DT  F 4 2   ? 154.198 139.543 155.449 1.00 230.35 ?  22  DT  F C7    1 
ATOM 8006 C C6    . DT  F 4 2   ? 154.866 137.152 155.513 1.00 230.35 ?  22  DT  F C6    1 
ATOM 8007 P P     . DC  F 4 3   ? 158.471 132.661 153.065 1.00 223.26 ?  23  DC  F P     1 
ATOM 8008 O OP1   . DC  F 4 3   ? 159.238 131.396 153.063 1.00 223.26 ?  23  DC  F OP1   1 
ATOM 8009 O OP2   . DC  F 4 3   ? 158.982 133.832 152.320 1.00 223.26 -1 23  DC  F OP2   1 
ATOM 8010 O "O5'" . DC  F 4 3   ? 156.985 132.364 152.557 1.00 223.26 ?  23  DC  F "O5'" 1 
ATOM 8011 C "C5'" . DC  F 4 3   ? 156.126 131.540 153.333 1.00 223.26 ?  23  DC  F "C5'" 1 
ATOM 8012 C "C4'" . DC  F 4 3   ? 154.739 131.483 152.725 1.00 223.26 ?  23  DC  F "C4'" 1 
ATOM 8013 O "O4'" . DC  F 4 3   ? 153.975 132.623 153.144 1.00 223.26 ?  23  DC  F "O4'" 1 
ATOM 8014 C "C3'" . DC  F 4 3   ? 154.702 131.540 151.208 1.00 223.26 ?  23  DC  F "C3'" 1 
ATOM 8015 O "O3'" . DC  F 4 3   ? 154.762 130.221 150.678 1.00 223.26 ?  23  DC  F "O3'" 1 
ATOM 8016 C "C2'" . DC  F 4 3   ? 153.355 132.221 150.900 1.00 223.26 ?  23  DC  F "C2'" 1 
ATOM 8017 C "C1'" . DC  F 4 3   ? 152.892 132.764 152.259 1.00 223.26 ?  23  DC  F "C1'" 1 
ATOM 8018 N N1    . DC  F 4 3   ? 152.485 134.197 152.222 1.00 223.26 ?  23  DC  F N1    1 
ATOM 8019 C C2    . DC  F 4 3   ? 151.127 134.529 152.188 1.00 223.26 ?  23  DC  F C2    1 
ATOM 8020 O O2    . DC  F 4 3   ? 150.285 133.624 152.190 1.00 223.26 ?  23  DC  F O2    1 
ATOM 8021 N N3    . DC  F 4 3   ? 150.772 135.836 152.155 1.00 223.26 ?  23  DC  F N3    1 
ATOM 8022 C C4    . DC  F 4 3   ? 151.711 136.782 152.154 1.00 223.26 ?  23  DC  F C4    1 
ATOM 8023 N N4    . DC  F 4 3   ? 151.313 138.058 152.121 1.00 223.26 ?  23  DC  F N4    1 
ATOM 8024 C C5    . DC  F 4 3   ? 153.100 136.463 152.188 1.00 223.26 ?  23  DC  F C5    1 
ATOM 8025 C C6    . DC  F 4 3   ? 153.439 135.171 152.219 1.00 223.26 ?  23  DC  F C6    1 
ATOM 8026 P P     . DT  F 4 4   ? 154.674 129.973 149.093 1.00 216.68 ?  24  DT  F P     1 
ATOM 8027 O OP1   . DT  F 4 4   ? 155.333 128.679 148.808 1.00 216.68 ?  24  DT  F OP1   1 
ATOM 8028 O OP2   . DT  F 4 4   ? 155.138 131.201 148.411 1.00 216.68 -1 24  DT  F OP2   1 
ATOM 8029 O "O5'" . DT  F 4 4   ? 153.107 129.820 148.823 1.00 216.68 ?  24  DT  F "O5'" 1 
ATOM 8030 C "C5'" . DT  F 4 4   ? 152.313 129.041 149.707 1.00 216.68 ?  24  DT  F "C5'" 1 
ATOM 8031 C "C4'" . DT  F 4 4   ? 150.842 129.365 149.536 1.00 216.68 ?  24  DT  F "C4'" 1 
ATOM 8032 O "O4'" . DT  F 4 4   ? 150.593 130.735 149.926 1.00 216.68 ?  24  DT  F "O4'" 1 
ATOM 8033 C "C3'" . DT  F 4 4   ? 150.316 129.228 148.103 1.00 216.68 ?  24  DT  F "C3'" 1 
ATOM 8034 O "O3'" . DT  F 4 4   ? 149.313 128.224 148.050 1.00 216.68 ?  24  DT  F "O3'" 1 
ATOM 8035 C "C2'" . DT  F 4 4   ? 149.752 130.617 147.767 1.00 216.68 ?  24  DT  F "C2'" 1 
ATOM 8036 C "C1'" . DT  F 4 4   ? 149.542 131.229 149.142 1.00 216.68 ?  24  DT  F "C1'" 1 
ATOM 8037 N N1    . DT  F 4 4   ? 149.596 132.719 149.141 1.00 216.68 ?  24  DT  F N1    1 
ATOM 8038 C C2    . DT  F 4 4   ? 148.477 133.432 149.503 1.00 216.68 ?  24  DT  F C2    1 
ATOM 8039 O O2    . DT  F 4 4   ? 147.432 132.907 149.840 1.00 216.68 ?  24  DT  F O2    1 
ATOM 8040 N N3    . DT  F 4 4   ? 148.626 134.791 149.462 1.00 216.68 ?  24  DT  F N3    1 
ATOM 8041 C C4    . DT  F 4 4   ? 149.758 135.496 149.099 1.00 216.68 ?  24  DT  F C4    1 
ATOM 8042 O O4    . DT  F 4 4   ? 149.793 136.722 149.094 1.00 216.68 ?  24  DT  F O4    1 
ATOM 8043 C C5    . DT  F 4 4   ? 150.894 134.688 148.725 1.00 216.68 ?  24  DT  F C5    1 
ATOM 8044 C C7    . DT  F 4 4   ? 152.179 135.340 148.311 1.00 216.68 ?  24  DT  F C7    1 
ATOM 8045 C C6    . DT  F 4 4   ? 150.759 133.354 148.762 1.00 216.68 ?  24  DT  F C6    1 
ATOM 8046 P P     . DC  F 4 5   ? 148.623 127.844 146.650 1.00 208.33 ?  25  DC  F P     1 
ATOM 8047 O OP1   . DC  F 4 5   ? 148.113 126.460 146.763 1.00 208.33 ?  25  DC  F OP1   1 
ATOM 8048 O OP2   . DC  F 4 5   ? 149.570 128.193 145.569 1.00 208.33 -1 25  DC  F OP2   1 
ATOM 8049 O "O5'" . DC  F 4 5   ? 147.381 128.845 146.558 1.00 208.33 ?  25  DC  F "O5'" 1 
ATOM 8050 C "C5'" . DC  F 4 5   ? 146.537 129.025 147.686 1.00 208.33 ?  25  DC  F "C5'" 1 
ATOM 8051 C "C4'" . DC  F 4 5   ? 145.617 130.214 147.484 1.00 208.33 ?  25  DC  F "C4'" 1 
ATOM 8052 O "O4'" . DC  F 4 5   ? 146.380 131.439 147.546 1.00 208.33 ?  25  DC  F "O4'" 1 
ATOM 8053 C "C3'" . DC  F 4 5   ? 144.885 130.238 146.138 1.00 208.33 ?  25  DC  F "C3'" 1 
ATOM 8054 O "O3'" . DC  F 4 5   ? 143.487 130.129 146.346 1.00 208.33 ?  25  DC  F "O3'" 1 
ATOM 8055 C "C2'" . DC  F 4 5   ? 145.262 131.593 145.519 1.00 208.33 ?  25  DC  F "C2'" 1 
ATOM 8056 C "C1'" . DC  F 4 5   ? 145.758 132.382 146.720 1.00 208.33 ?  25  DC  F "C1'" 1 
ATOM 8057 N N1    . DC  F 4 5   ? 146.745 133.441 146.372 1.00 208.33 ?  25  DC  F N1    1 
ATOM 8058 C C2    . DC  F 4 5   ? 146.374 134.784 146.466 1.00 208.33 ?  25  DC  F C2    1 
ATOM 8059 O O2    . DC  F 4 5   ? 145.230 135.066 146.838 1.00 208.33 ?  25  DC  F O2    1 
ATOM 8060 N N3    . DC  F 4 5   ? 147.279 135.740 146.147 1.00 208.33 ?  25  DC  F N3    1 
ATOM 8061 C C4    . DC  F 4 5   ? 148.503 135.392 145.748 1.00 208.33 ?  25  DC  F C4    1 
ATOM 8062 N N4    . DC  F 4 5   ? 149.363 136.369 145.443 1.00 208.33 ?  25  DC  F N4    1 
ATOM 8063 C C5    . DC  F 4 5   ? 148.900 134.027 145.644 1.00 208.33 ?  25  DC  F C5    1 
ATOM 8064 C C6    . DC  F 4 5   ? 147.997 133.094 145.962 1.00 208.33 ?  25  DC  F C6    1 
ATOM 8065 P P     . DG  F 4 6   ? 142.592 129.249 145.345 1.00 197.10 ?  26  DG  F P     1 
ATOM 8066 O OP1   . DG  F 4 6   ? 141.740 128.362 146.166 1.00 197.10 ?  26  DG  F OP1   1 
ATOM 8067 O OP2   . DG  F 4 6   ? 143.501 128.665 144.334 1.00 197.10 -1 26  DG  F OP2   1 
ATOM 8068 O "O5'" . DG  F 4 6   ? 141.668 130.327 144.611 1.00 197.10 ?  26  DG  F "O5'" 1 
ATOM 8069 C "C5'" . DG  F 4 6   ? 140.800 131.155 145.374 1.00 197.10 ?  26  DG  F "C5'" 1 
ATOM 8070 C "C4'" . DG  F 4 6   ? 140.639 132.512 144.717 1.00 197.10 ?  26  DG  F "C4'" 1 
ATOM 8071 O "O4'" . DG  F 4 6   ? 141.913 133.175 144.677 1.00 197.10 ?  26  DG  F "O4'" 1 
ATOM 8072 C "C3'" . DG  F 4 6   ? 140.168 132.468 143.268 1.00 197.10 ?  26  DG  F "C3'" 1 
ATOM 8073 O "O3'" . DG  F 4 6   ? 138.722 132.627 143.165 1.00 197.10 ?  26  DG  F "O3'" 1 
ATOM 8074 C "C2'" . DG  F 4 6   ? 140.940 133.598 142.569 1.00 197.10 ?  26  DG  F "C2'" 1 
ATOM 8075 C "C1'" . DG  F 4 6   ? 141.903 134.121 143.637 1.00 197.10 ?  26  DG  F "C1'" 1 
ATOM 8076 N N9    . DG  F 4 6   ? 143.271 134.283 143.153 1.00 197.10 ?  26  DG  F N9    1 
ATOM 8077 C C8    . DG  F 4 6   ? 144.160 133.282 142.851 1.00 197.10 ?  26  DG  F C8    1 
ATOM 8078 N N7    . DG  F 4 6   ? 145.316 133.719 142.441 1.00 197.10 ?  26  DG  F N7    1 
ATOM 8079 C C5    . DG  F 4 6   ? 145.187 135.100 142.468 1.00 197.10 ?  26  DG  F C5    1 
ATOM 8080 C C6    . DG  F 4 6   ? 146.119 136.107 142.128 1.00 197.10 ?  26  DG  F C6    1 
ATOM 8081 O O6    . DG  F 4 6   ? 147.280 135.970 141.720 1.00 197.10 ?  26  DG  F O6    1 
ATOM 8082 N N1    . DG  F 4 6   ? 145.587 137.381 142.298 1.00 197.10 ?  26  DG  F N1    1 
ATOM 8083 C C2    . DG  F 4 6   ? 144.317 137.648 142.745 1.00 197.10 ?  26  DG  F C2    1 
ATOM 8084 N N2    . DG  F 4 6   ? 143.983 138.943 142.836 1.00 197.10 ?  26  DG  F N2    1 
ATOM 8085 N N3    . DG  F 4 6   ? 143.429 136.713 143.065 1.00 197.10 ?  26  DG  F N3    1 
ATOM 8086 C C4    . DG  F 4 6   ? 143.933 135.466 142.905 1.00 197.10 ?  26  DG  F C4    1 
ATOM 8087 P P     . DA  F 4 7   ? 137.924 133.898 143.766 1.00 199.90 ?  27  DA  F P     1 
ATOM 8088 O OP1   . DA  F 4 7   ? 138.184 134.071 145.210 1.00 199.90 ?  27  DA  F OP1   1 
ATOM 8089 O OP2   . DA  F 4 7   ? 136.525 133.707 143.334 1.00 199.90 -1 27  DA  F OP2   1 
ATOM 8090 O "O5'" . DA  F 4 7   ? 138.473 135.171 142.962 1.00 199.90 ?  27  DA  F "O5'" 1 
ATOM 8091 C "C5'" . DA  F 4 7   ? 138.205 136.481 143.460 1.00 199.90 ?  27  DA  F "C5'" 1 
ATOM 8092 C "C4'" . DA  F 4 7   ? 138.723 137.563 142.524 1.00 199.90 ?  27  DA  F "C4'" 1 
ATOM 8093 O "O4'" . DA  F 4 7   ? 140.128 137.355 142.240 1.00 199.90 ?  27  DA  F "O4'" 1 
ATOM 8094 C "C3'" . DA  F 4 7   ? 138.021 137.658 141.162 1.00 199.90 ?  27  DA  F "C3'" 1 
ATOM 8095 O "O3'" . DA  F 4 7   ? 137.523 138.980 140.978 1.00 199.90 ?  27  DA  F "O3'" 1 
ATOM 8096 C "C2'" . DA  F 4 7   ? 139.130 137.328 140.156 1.00 199.90 ?  27  DA  F "C2'" 1 
ATOM 8097 C "C1'" . DA  F 4 7   ? 140.370 137.752 140.917 1.00 199.90 ?  27  DA  F "C1'" 1 
ATOM 8098 N N9    . DA  F 4 7   ? 141.591 137.105 140.454 1.00 199.90 ?  27  DA  F N9    1 
ATOM 8099 C C8    . DA  F 4 7   ? 141.814 135.765 140.339 1.00 199.90 ?  27  DA  F C8    1 
ATOM 8100 N N7    . DA  F 4 7   ? 143.009 135.462 139.901 1.00 199.90 ?  27  DA  F N7    1 
ATOM 8101 C C5    . DA  F 4 7   ? 143.613 136.690 139.710 1.00 199.90 ?  27  DA  F C5    1 
ATOM 8102 C C6    . DA  F 4 7   ? 144.892 137.052 139.256 1.00 199.90 ?  27  DA  F C6    1 
ATOM 8103 N N6    . DA  F 4 7   ? 145.819 136.161 138.898 1.00 199.90 ?  27  DA  F N6    1 
ATOM 8104 N N1    . DA  F 4 7   ? 145.181 138.369 139.182 1.00 199.90 ?  27  DA  F N1    1 
ATOM 8105 C C2    . DA  F 4 7   ? 144.245 139.255 139.545 1.00 199.90 ?  27  DA  F C2    1 
ATOM 8106 N N3    . DA  F 4 7   ? 143.007 139.033 139.986 1.00 199.90 ?  27  DA  F N3    1 
ATOM 8107 C C4    . DA  F 4 7   ? 142.752 137.716 140.045 1.00 199.90 ?  27  DA  F C4    1 
ATOM 8108 P P     . DG  F 4 8   ? 136.596 139.348 139.716 1.00 210.42 ?  28  DG  F P     1 
ATOM 8109 O OP1   . DG  F 4 8   ? 135.373 139.985 140.251 1.00 210.42 ?  28  DG  F OP1   1 
ATOM 8110 O OP2   . DG  F 4 8   ? 136.471 138.160 138.843 1.00 210.42 -1 28  DG  F OP2   1 
ATOM 8111 O "O5'" . DG  F 4 8   ? 137.445 140.458 138.935 1.00 210.42 ?  28  DG  F "O5'" 1 
ATOM 8112 C "C5'" . DG  F 4 8   ? 137.760 141.689 139.580 1.00 210.42 ?  28  DG  F "C5'" 1 
ATOM 8113 C "C4'" . DG  F 4 8   ? 138.888 142.413 138.862 1.00 210.42 ?  28  DG  F "C4'" 1 
ATOM 8114 O "O4'" . DG  F 4 8   ? 140.066 141.565 138.824 1.00 210.42 ?  28  DG  F "O4'" 1 
ATOM 8115 C "C3'" . DG  F 4 8   ? 138.595 142.801 137.412 1.00 210.42 ?  28  DG  F "C3'" 1 
ATOM 8116 O "O3'" . DG  F 4 8   ? 139.100 144.104 137.149 1.00 210.42 ?  28  DG  F "O3'" 1 
ATOM 8117 C "C2'" . DG  F 4 8   ? 139.343 141.740 136.611 1.00 210.42 ?  28  DG  F "C2'" 1 
ATOM 8118 C "C1'" . DG  F 4 8   ? 140.546 141.484 137.501 1.00 210.42 ?  28  DG  F "C1'" 1 
ATOM 8119 N N9    . DG  F 4 8   ? 141.137 140.167 137.308 1.00 210.42 ?  28  DG  F N9    1 
ATOM 8120 C C8    . DG  F 4 8   ? 140.539 138.953 137.540 1.00 210.42 ?  28  DG  F C8    1 
ATOM 8121 N N7    . DG  F 4 8   ? 141.309 137.936 137.278 1.00 210.42 ?  28  DG  F N7    1 
ATOM 8122 C C5    . DG  F 4 8   ? 142.496 138.512 136.847 1.00 210.42 ?  28  DG  F C5    1 
ATOM 8123 C C6    . DG  F 4 8   ? 143.700 137.905 136.427 1.00 210.42 ?  28  DG  F C6    1 
ATOM 8124 O O6    . DG  F 4 8   ? 143.962 136.698 136.353 1.00 210.42 ?  28  DG  F O6    1 
ATOM 8125 N N1    . DG  F 4 8   ? 144.659 138.849 136.074 1.00 210.42 ?  28  DG  F N1    1 
ATOM 8126 C C2    . DG  F 4 8   ? 144.476 140.210 136.121 1.00 210.42 ?  28  DG  F C2    1 
ATOM 8127 N N2    . DG  F 4 8   ? 145.517 140.963 135.739 1.00 210.42 ?  28  DG  F N2    1 
ATOM 8128 N N3    . DG  F 4 8   ? 143.350 140.793 136.512 1.00 210.42 ?  28  DG  F N3    1 
ATOM 8129 C C4    . DG  F 4 8   ? 142.407 139.885 136.860 1.00 210.42 ?  28  DG  F C4    1 
ATOM 8130 P P     . DT  F 4 9   ? 138.922 144.764 135.695 1.00 217.82 ?  29  DT  F P     1 
ATOM 8131 O OP1   . DT  F 4 9   ? 138.882 146.232 135.876 1.00 217.82 ?  29  DT  F OP1   1 
ATOM 8132 O OP2   . DT  F 4 9   ? 137.799 144.078 135.018 1.00 217.82 -1 29  DT  F OP2   1 
ATOM 8133 O "O5'" . DT  F 4 9   ? 140.272 144.379 134.928 1.00 217.82 ?  29  DT  F "O5'" 1 
ATOM 8134 C "C5'" . DT  F 4 9   ? 141.524 144.854 135.412 1.00 217.82 ?  29  DT  F "C5'" 1 
ATOM 8135 C "C4'" . DT  F 4 9   ? 142.604 144.721 134.352 1.00 217.82 ?  29  DT  F "C4'" 1 
ATOM 8136 O "O4'" . DT  F 4 9   ? 143.150 143.375 134.371 1.00 217.82 ?  29  DT  F "O4'" 1 
ATOM 8137 C "C3'" . DT  F 4 9   ? 142.140 144.970 132.917 1.00 217.82 ?  29  DT  F "C3'" 1 
ATOM 8138 O "O3'" . DT  F 4 9   ? 143.127 145.711 132.212 1.00 217.82 ?  29  DT  F "O3'" 1 
ATOM 8139 C "C2'" . DT  F 4 9   ? 141.990 143.559 132.354 1.00 217.82 ?  29  DT  F "C2'" 1 
ATOM 8140 C "C1'" . DT  F 4 9   ? 143.115 142.833 133.070 1.00 217.82 ?  29  DT  F "C1'" 1 
ATOM 8141 N N1    . DT  F 4 9   ? 142.903 141.365 133.185 1.00 217.82 ?  29  DT  F N1    1 
ATOM 8142 C C2    . DT  F 4 9   ? 143.936 140.510 132.879 1.00 217.82 ?  29  DT  F C2    1 
ATOM 8143 O O2    . DT  F 4 9   ? 145.031 140.891 132.508 1.00 217.82 ?  29  DT  F O2    1 
ATOM 8144 N N3    . DT  F 4 9   ? 143.640 139.181 133.023 1.00 217.82 ?  29  DT  F N3    1 
ATOM 8145 C C4    . DT  F 4 9   ? 142.439 138.635 133.435 1.00 217.82 ?  29  DT  F C4    1 
ATOM 8146 O O4    . DT  F 4 9   ? 142.268 137.424 133.534 1.00 217.82 ?  29  DT  F O4    1 
ATOM 8147 C C5    . DT  F 4 9   ? 141.399 139.587 133.741 1.00 217.82 ?  29  DT  F C5    1 
ATOM 8148 C C7    . DT  F 4 9   ? 140.052 139.111 134.196 1.00 217.82 ?  29  DT  F C7    1 
ATOM 8149 C C6    . DT  F 4 9   ? 141.678 140.890 133.604 1.00 217.82 ?  29  DT  F C6    1 
ATOM 8150 P P     . DC  F 4 10  ? 142.736 146.508 130.873 1.00 218.40 ?  30  DC  F P     1 
ATOM 8151 O OP1   . DC  F 4 10  ? 143.280 147.878 130.994 1.00 218.40 ?  30  DC  F OP1   1 
ATOM 8152 O OP2   . DC  F 4 10  ? 141.289 146.309 130.637 1.00 218.40 -1 30  DC  F OP2   1 
ATOM 8153 O "O5'" . DC  F 4 10  ? 143.531 145.736 129.720 1.00 218.40 ?  30  DC  F "O5'" 1 
ATOM 8154 C "C5'" . DC  F 4 10  ? 144.953 145.782 129.685 1.00 218.40 ?  30  DC  F "C5'" 1 
ATOM 8155 C "C4'" . DC  F 4 10  ? 145.507 144.630 128.867 1.00 218.40 ?  30  DC  F "C4'" 1 
ATOM 8156 O "O4'" . DC  F 4 10  ? 145.275 143.396 129.566 1.00 218.40 ?  30  DC  F "O4'" 1 
ATOM 8157 C "C3'" . DC  F 4 10  ? 144.849 144.437 127.512 1.00 218.40 ?  30  DC  F "C3'" 1 
ATOM 8158 O "O3'" . DC  F 4 10  ? 145.515 145.239 126.510 1.00 218.40 ?  30  DC  F "O3'" 1 
ATOM 8159 C "C2'" . DC  F 4 10  ? 144.988 142.933 127.248 1.00 218.40 ?  30  DC  F "C2'" 1 
ATOM 8160 C "C1'" . DC  F 4 10  ? 145.224 142.332 128.639 1.00 218.40 ?  30  DC  F "C1'" 1 
ATOM 8161 N N1    . DC  F 4 10  ? 144.161 141.384 129.074 1.00 218.40 ?  30  DC  F N1    1 
ATOM 8162 C C2    . DC  F 4 10  ? 144.424 140.011 129.087 1.00 218.40 ?  30  DC  F C2    1 
ATOM 8163 O O2    . DC  F 4 10  ? 145.535 139.607 128.724 1.00 218.40 ?  30  DC  F O2    1 
ATOM 8164 N N3    . DC  F 4 10  ? 143.449 139.161 129.492 1.00 218.40 ?  30  DC  F N3    1 
ATOM 8165 C C4    . DC  F 4 10  ? 142.265 139.637 129.876 1.00 218.40 ?  30  DC  F C4    1 
ATOM 8166 N N4    . DC  F 4 10  ? 141.336 138.760 130.269 1.00 218.40 ?  30  DC  F N4    1 
ATOM 8167 C C5    . DC  F 4 10  ? 141.980 141.034 129.873 1.00 218.40 ?  30  DC  F C5    1 
ATOM 8168 C C6    . DC  F 4 10  ? 142.948 141.862 129.469 1.00 218.40 ?  30  DC  F C6    1 
ATOM 8169 P P     . DT  F 4 11  ? 146.901 144.780 125.825 1.00 210.42 ?  31  DT  F P     1 
ATOM 8170 O OP1   . DT  F 4 11  ? 147.782 144.127 126.820 1.00 210.42 ?  31  DT  F OP1   1 
ATOM 8171 O OP2   . DT  F 4 11  ? 147.409 145.962 125.098 1.00 210.42 -1 31  DT  F OP2   1 
ATOM 8172 O "O5'" . DT  F 4 11  ? 146.463 143.709 124.720 1.00 210.42 ?  31  DT  F "O5'" 1 
ATOM 8173 C "C5'" . DT  F 4 11  ? 147.390 143.298 123.722 1.00 210.42 ?  31  DT  F "C5'" 1 
ATOM 8174 C "C4'" . DT  F 4 11  ? 147.605 141.795 123.765 1.00 210.42 ?  31  DT  F "C4'" 1 
ATOM 8175 O "O4'" . DT  F 4 11  ? 146.663 141.195 124.683 1.00 210.42 ?  31  DT  F "O4'" 1 
ATOM 8176 C "C3'" . DT  F 4 11  ? 147.415 141.079 122.424 1.00 210.42 ?  31  DT  F "C3'" 1 
ATOM 8177 O "O3'" . DT  F 4 11  ? 148.623 140.444 122.027 1.00 210.42 ?  31  DT  F "O3'" 1 
ATOM 8178 C "C2'" . DT  F 4 11  ? 146.298 140.059 122.683 1.00 210.42 ?  31  DT  F "C2'" 1 
ATOM 8179 C "C1'" . DT  F 4 11  ? 146.298 139.932 124.198 1.00 210.42 ?  31  DT  F "C1'" 1 
ATOM 8180 N N1    . DT  F 4 11  ? 144.963 139.584 124.753 1.00 210.42 ?  31  DT  F N1    1 
ATOM 8181 C C2    . DT  F 4 11  ? 144.664 138.270 125.020 1.00 210.42 ?  31  DT  F C2    1 
ATOM 8182 O O2    . DT  F 4 11  ? 145.444 137.354 124.828 1.00 210.42 ?  31  DT  F O2    1 
ATOM 8183 N N3    . DT  F 4 11  ? 143.409 138.062 125.527 1.00 210.42 ?  31  DT  F N3    1 
ATOM 8184 C C4    . DT  F 4 11  ? 142.444 139.018 125.785 1.00 210.42 ?  31  DT  F C4    1 
ATOM 8185 O O4    . DT  F 4 11  ? 141.343 138.733 126.242 1.00 210.42 ?  31  DT  F O4    1 
ATOM 8186 C C5    . DT  F 4 11  ? 142.823 140.375 125.480 1.00 210.42 ?  31  DT  F C5    1 
ATOM 8187 C C7    . DT  F 4 11  ? 141.860 141.500 125.718 1.00 210.42 ?  31  DT  F C7    1 
ATOM 8188 C C6    . DT  F 4 11  ? 144.048 140.589 124.981 1.00 210.42 ?  31  DT  F C6    1 
ATOM 8189 P P     . DA  F 4 12  ? 148.959 140.260 120.466 1.00 200.33 ?  32  DA  F P     1 
ATOM 8190 O OP1   . DA  F 4 12  ? 150.431 140.259 120.320 1.00 200.33 ?  32  DA  F OP1   1 
ATOM 8191 O OP2   . DA  F 4 12  ? 148.144 141.240 119.716 1.00 200.33 -1 32  DA  F OP2   1 
ATOM 8192 O "O5'" . DA  F 4 12  ? 148.406 138.799 120.120 1.00 200.33 ?  32  DA  F "O5'" 1 
ATOM 8193 C "C5'" . DA  F 4 12  ? 149.084 137.648 120.610 1.00 200.33 ?  32  DA  F "C5'" 1 
ATOM 8194 C "C4'" . DA  F 4 12  ? 148.307 136.380 120.296 1.00 200.33 ?  32  DA  F "C4'" 1 
ATOM 8195 O "O4'" . DA  F 4 12  ? 146.981 136.463 120.880 1.00 200.33 ?  32  DA  F "O4'" 1 
ATOM 8196 C "C3'" . DA  F 4 12  ? 148.091 136.096 118.812 1.00 200.33 ?  32  DA  F "C3'" 1 
ATOM 8197 O "O3'" . DA  F 4 12  ? 148.124 134.693 118.587 1.00 200.33 ?  32  DA  F "O3'" 1 
ATOM 8198 C "C2'" . DA  F 4 12  ? 146.700 136.668 118.562 1.00 200.33 ?  32  DA  F "C2'" 1 
ATOM 8199 C "C1'" . DA  F 4 12  ? 146.002 136.332 119.870 1.00 200.33 ?  32  DA  F "C1'" 1 
ATOM 8200 N N9    . DA  F 4 12  ? 144.898 137.228 120.188 1.00 200.33 ?  32  DA  F N9    1 
ATOM 8201 C C8    . DA  F 4 12  ? 144.872 138.586 120.048 1.00 200.33 ?  32  DA  F C8    1 
ATOM 8202 N N7    . DA  F 4 12  ? 143.743 139.135 120.425 1.00 200.33 ?  32  DA  F N7    1 
ATOM 8203 C C5    . DA  F 4 12  ? 142.975 138.062 120.841 1.00 200.33 ?  32  DA  F C5    1 
ATOM 8204 C C6    . DA  F 4 12  ? 141.669 137.973 121.356 1.00 200.33 ?  32  DA  F C6    1 
ATOM 8205 N N6    . DA  F 4 12  ? 140.879 139.035 121.543 1.00 200.33 ?  32  DA  F N6    1 
ATOM 8206 N N1    . DA  F 4 12  ? 141.204 136.748 121.671 1.00 200.33 ?  32  DA  F N1    1 
ATOM 8207 C C2    . DA  F 4 12  ? 141.999 135.688 121.483 1.00 200.33 ?  32  DA  F C2    1 
ATOM 8208 N N3    . DA  F 4 12  ? 143.241 135.647 121.007 1.00 200.33 ?  32  DA  F N3    1 
ATOM 8209 C C4    . DA  F 4 12  ? 143.674 136.879 120.703 1.00 200.33 ?  32  DA  F C4    1 
ATOM 8210 P P     . DG  F 4 13  ? 148.233 134.103 117.096 1.00 197.81 ?  33  DG  F P     1 
ATOM 8211 O OP1   . DG  F 4 13  ? 149.473 133.299 117.031 1.00 197.81 ?  33  DG  F OP1   1 
ATOM 8212 O OP2   . DG  F 4 13  ? 148.026 135.207 116.134 1.00 197.81 -1 33  DG  F OP2   1 
ATOM 8213 O "O5'" . DG  F 4 13  ? 146.981 133.116 116.993 1.00 197.81 ?  33  DG  F "O5'" 1 
ATOM 8214 C "C5'" . DG  F 4 13  ? 146.836 132.058 117.932 1.00 197.81 ?  33  DG  F "C5'" 1 
ATOM 8215 C "C4'" . DG  F 4 13  ? 145.390 131.604 118.020 1.00 197.81 ?  33  DG  F "C4'" 1 
ATOM 8216 O "O4'" . DG  F 4 13  ? 144.565 132.693 118.517 1.00 197.81 ?  33  DG  F "O4'" 1 
ATOM 8217 C "C3'" . DG  F 4 13  ? 144.762 131.173 116.693 1.00 197.81 ?  33  DG  F "C3'" 1 
ATOM 8218 O "O3'" . DG  F 4 13  ? 143.926 130.041 116.902 1.00 197.81 ?  33  DG  F "O3'" 1 
ATOM 8219 C "C2'" . DG  F 4 13  ? 143.948 132.398 116.294 1.00 197.81 ?  33  DG  F "C2'" 1 
ATOM 8220 C "C1'" . DG  F 4 13  ? 143.467 132.870 117.653 1.00 197.81 ?  33  DG  F "C1'" 1 
ATOM 8221 N N9    . DG  F 4 13  ? 143.068 134.273 117.682 1.00 197.81 ?  33  DG  F N9    1 
ATOM 8222 C C8    . DG  F 4 13  ? 143.810 135.355 117.280 1.00 197.81 ?  33  DG  F C8    1 
ATOM 8223 N N7    . DG  F 4 13  ? 143.189 136.493 117.425 1.00 197.81 ?  33  DG  F N7    1 
ATOM 8224 C C5    . DG  F 4 13  ? 141.957 136.141 117.958 1.00 197.81 ?  33  DG  F C5    1 
ATOM 8225 C C6    . DG  F 4 13  ? 140.858 136.951 118.327 1.00 197.81 ?  33  DG  F C6    1 
ATOM 8226 O O6    . DG  F 4 13  ? 140.754 138.182 118.254 1.00 197.81 ?  33  DG  F O6    1 
ATOM 8227 N N1    . DG  F 4 13  ? 139.804 136.191 118.826 1.00 197.81 ?  33  DG  F N1    1 
ATOM 8228 C C2    . DG  F 4 13  ? 139.812 134.823 118.952 1.00 197.81 ?  33  DG  F C2    1 
ATOM 8229 N N2    . DG  F 4 13  ? 138.702 134.265 119.455 1.00 197.81 ?  33  DG  F N2    1 
ATOM 8230 N N3    . DG  F 4 13  ? 140.834 134.053 118.609 1.00 197.81 ?  33  DG  F N3    1 
ATOM 8231 C C4    . DG  F 4 13  ? 141.868 134.778 118.122 1.00 197.81 ?  33  DG  F C4    1 
ATOM 8232 P P     . DA  F 4 14  ? 143.516 129.095 115.669 1.00 198.11 ?  34  DA  F P     1 
ATOM 8233 O OP1   . DA  F 4 14  ? 144.103 127.762 115.921 1.00 198.11 ?  34  DA  F OP1   1 
ATOM 8234 O OP2   . DA  F 4 14  ? 143.833 129.813 114.415 1.00 198.11 -1 34  DA  F OP2   1 
ATOM 8235 O "O5'" . DA  F 4 14  ? 141.924 128.984 115.784 1.00 198.11 ?  34  DA  F "O5'" 1 
ATOM 8236 C "C5'" . DA  F 4 14  ? 141.336 128.294 116.881 1.00 198.11 ?  34  DA  F "C5'" 1 
ATOM 8237 C "C4'" . DA  F 4 14  ? 139.860 128.633 117.016 1.00 198.11 ?  34  DA  F "C4'" 1 
ATOM 8238 O "O4'" . DA  F 4 14  ? 139.703 130.062 117.216 1.00 198.11 ?  34  DA  F "O4'" 1 
ATOM 8239 C "C3'" . DA  F 4 14  ? 138.997 128.288 115.808 1.00 198.11 ?  34  DA  F "C3'" 1 
ATOM 8240 O "O3'" . DA  F 4 14  ? 137.695 127.915 116.242 1.00 198.11 ?  34  DA  F "O3'" 1 
ATOM 8241 C "C2'" . DA  F 4 14  ? 138.971 129.600 115.033 1.00 198.11 ?  34  DA  F "C2'" 1 
ATOM 8242 C "C1'" . DA  F 4 14  ? 138.938 130.617 116.164 1.00 198.11 ?  34  DA  F "C1'" 1 
ATOM 8243 N N9    . DA  F 4 14  ? 139.524 131.904 115.811 1.00 198.11 ?  34  DA  F N9    1 
ATOM 8244 C C8    . DA  F 4 14  ? 140.766 132.127 115.291 1.00 198.11 ?  34  DA  F C8    1 
ATOM 8245 N N7    . DA  F 4 14  ? 141.033 133.393 115.080 1.00 198.11 ?  34  DA  F N7    1 
ATOM 8246 C C5    . DA  F 4 14  ? 139.886 134.047 115.494 1.00 198.11 ?  34  DA  F C5    1 
ATOM 8247 C C6    . DA  F 4 14  ? 139.532 135.408 115.529 1.00 198.11 ?  34  DA  F C6    1 
ATOM 8248 N N6    . DA  F 4 14  ? 140.341 136.389 115.119 1.00 198.11 ?  34  DA  F N6    1 
ATOM 8249 N N1    . DA  F 4 14  ? 138.308 135.722 116.001 1.00 198.11 ?  34  DA  F N1    1 
ATOM 8250 C C2    . DA  F 4 14  ? 137.501 134.736 116.409 1.00 198.11 ?  34  DA  F C2    1 
ATOM 8251 N N3    . DA  F 4 14  ? 137.724 133.424 116.425 1.00 198.11 ?  34  DA  F N3    1 
ATOM 8252 C C4    . DA  F 4 14  ? 138.946 133.144 115.950 1.00 198.11 ?  34  DA  F C4    1 
ATOM 8253 P P     . DA  F 4 15  ? 136.686 127.169 115.239 1.00 199.80 ?  35  DA  F P     1 
ATOM 8254 O OP1   . DA  F 4 15  ? 136.185 125.961 115.930 1.00 199.80 ?  35  DA  F OP1   1 
ATOM 8255 O OP2   . DA  F 4 15  ? 137.356 127.040 113.926 1.00 199.80 -1 35  DA  F OP2   1 
ATOM 8256 O "O5'" . DA  F 4 15  ? 135.478 128.202 115.075 1.00 199.80 ?  35  DA  F "O5'" 1 
ATOM 8257 C "C5'" . DA  F 4 15  ? 134.689 128.557 116.205 1.00 199.80 ?  35  DA  F "C5'" 1 
ATOM 8258 C "C4'" . DA  F 4 15  ? 133.756 129.711 115.879 1.00 199.80 ?  35  DA  F "C4'" 1 
ATOM 8259 O "O4'" . DA  F 4 15  ? 134.528 130.926 115.689 1.00 199.80 ?  35  DA  F "O4'" 1 
ATOM 8260 C "C3'" . DA  F 4 15  ? 132.927 129.538 114.609 1.00 199.80 ?  35  DA  F "C3'" 1 
ATOM 8261 O "O3'" . DA  F 4 15  ? 131.638 130.104 114.797 1.00 199.80 ?  35  DA  F "O3'" 1 
ATOM 8262 C "C2'" . DA  F 4 15  ? 133.732 130.318 113.576 1.00 199.80 ?  35  DA  F "C2'" 1 
ATOM 8263 C "C1'" . DA  F 4 15  ? 134.250 131.473 114.418 1.00 199.80 ?  35  DA  F "C1'" 1 
ATOM 8264 N N9    . DA  F 4 15  ? 135.474 132.075 113.901 1.00 199.80 ?  35  DA  F N9    1 
ATOM 8265 C C8    . DA  F 4 15  ? 136.606 131.423 113.503 1.00 199.80 ?  35  DA  F C8    1 
ATOM 8266 N N7    . DA  F 4 15  ? 137.560 132.222 113.088 1.00 199.80 ?  35  DA  F N7    1 
ATOM 8267 C C5    . DA  F 4 15  ? 137.015 133.487 113.225 1.00 199.80 ?  35  DA  F C5    1 
ATOM 8268 C C6    . DA  F 4 15  ? 137.522 134.772 112.953 1.00 199.80 ?  35  DA  F C6    1 
ATOM 8269 N N6    . DA  F 4 15  ? 138.747 134.991 112.466 1.00 199.80 ?  35  DA  F N6    1 
ATOM 8270 N N1    . DA  F 4 15  ? 136.719 135.826 113.203 1.00 199.80 ?  35  DA  F N1    1 
ATOM 8271 C C2    . DA  F 4 15  ? 135.493 135.602 113.691 1.00 199.80 ?  35  DA  F C2    1 
ATOM 8272 N N3    . DA  F 4 15  ? 134.908 134.442 113.985 1.00 199.80 ?  35  DA  F N3    1 
ATOM 8273 C C4    . DA  F 4 15  ? 135.730 133.414 113.727 1.00 199.80 ?  35  DA  F C4    1 
ATOM 8274 P P     . DA  F 4 16  ? 130.378 129.550 113.970 1.00 206.63 ?  36  DA  F P     1 
ATOM 8275 O OP1   . DA  F 4 16  ? 129.518 128.800 114.912 1.00 206.63 ?  36  DA  F OP1   1 
ATOM 8276 O OP2   . DA  F 4 16  ? 130.890 128.885 112.752 1.00 206.63 -1 36  DA  F OP2   1 
ATOM 8277 O "O5'" . DA  F 4 16  ? 129.609 130.877 113.519 1.00 206.63 ?  36  DA  F "O5'" 1 
ATOM 8278 C "C5'" . DA  F 4 16  ? 129.179 131.813 114.498 1.00 206.63 ?  36  DA  F "C5'" 1 
ATOM 8279 C "C4'" . DA  F 4 16  ? 129.024 133.198 113.894 1.00 206.63 ?  36  DA  F "C4'" 1 
ATOM 8280 O "O4'" . DA  F 4 16  ? 130.332 133.755 113.602 1.00 206.63 ?  36  DA  F "O4'" 1 
ATOM 8281 C "C3'" . DA  F 4 16  ? 128.235 133.252 112.588 1.00 206.63 ?  36  DA  F "C3'" 1 
ATOM 8282 O "O3'" . DA  F 4 16  ? 127.403 134.399 112.578 1.00 206.63 ?  36  DA  F "O3'" 1 
ATOM 8283 C "C2'" . DA  F 4 16  ? 129.328 133.339 111.525 1.00 206.63 ?  36  DA  F "C2'" 1 
ATOM 8284 C "C1'" . DA  F 4 16  ? 130.401 134.141 112.246 1.00 206.63 ?  36  DA  F "C1'" 1 
ATOM 8285 N N9    . DA  F 4 16  ? 131.754 133.868 111.767 1.00 206.63 ?  36  DA  F N9    1 
ATOM 8286 C C8    . DA  F 4 16  ? 132.344 132.644 111.630 1.00 206.63 ?  36  DA  F C8    1 
ATOM 8287 N N7    . DA  F 4 16  ? 133.576 132.696 111.183 1.00 206.63 ?  36  DA  F N7    1 
ATOM 8288 C C5    . DA  F 4 16  ? 133.812 134.049 111.016 1.00 206.63 ?  36  DA  F C5    1 
ATOM 8289 C C6    . DA  F 4 16  ? 134.938 134.767 110.566 1.00 206.63 ?  36  DA  F C6    1 
ATOM 8290 N N6    . DA  F 4 16  ? 136.080 134.183 110.191 1.00 206.63 ?  36  DA  F N6    1 
ATOM 8291 N N1    . DA  F 4 16  ? 134.844 136.112 110.521 1.00 206.63 ?  36  DA  F N1    1 
ATOM 8292 C C2    . DA  F 4 16  ? 133.699 136.692 110.900 1.00 206.63 ?  36  DA  F C2    1 
ATOM 8293 N N3    . DA  F 4 16  ? 132.576 136.123 111.338 1.00 206.63 ?  36  DA  F N3    1 
ATOM 8294 C C4    . DA  F 4 16  ? 132.700 134.788 111.374 1.00 206.63 ?  36  DA  F C4    1 
ATOM 8295 P P     . DT  F 4 17  ? 126.135 134.473 111.594 1.00 218.55 ?  37  DT  F P     1 
ATOM 8296 O OP1   . DT  F 4 17  ? 124.932 134.682 112.428 1.00 218.55 ?  37  DT  F OP1   1 
ATOM 8297 O OP2   . DT  F 4 17  ? 126.202 133.317 110.673 1.00 218.55 -1 37  DT  F OP2   1 
ATOM 8298 O "O5'" . DT  F 4 17  ? 126.402 135.796 110.741 1.00 218.55 ?  37  DT  F "O5'" 1 
ATOM 8299 C "C5'" . DT  F 4 17  ? 126.671 137.021 111.407 1.00 218.55 ?  37  DT  F "C5'" 1 
ATOM 8300 C "C4'" . DT  F 4 17  ? 127.215 138.052 110.438 1.00 218.55 ?  37  DT  F "C4'" 1 
ATOM 8301 O "O4'" . DT  F 4 17  ? 128.631 137.832 110.233 1.00 218.55 ?  37  DT  F "O4'" 1 
ATOM 8302 C "C3'" . DT  F 4 17  ? 126.568 138.037 109.050 1.00 218.55 ?  37  DT  F "C3'" 1 
ATOM 8303 O "O3'" . DT  F 4 17  ? 126.058 139.328 108.746 1.00 218.55 ?  37  DT  F "O3'" 1 
ATOM 8304 C "C2'" . DT  F 4 17  ? 127.709 137.630 108.107 1.00 218.55 ?  37  DT  F "C2'" 1 
ATOM 8305 C "C1'" . DT  F 4 17  ? 128.940 138.065 108.883 1.00 218.55 ?  37  DT  F "C1'" 1 
ATOM 8306 N N1    . DT  F 4 17  ? 130.176 137.294 108.546 1.00 218.55 ?  37  DT  F N1    1 
ATOM 8307 C C2    . DT  F 4 17  ? 131.305 137.974 108.153 1.00 218.55 ?  37  DT  F C2    1 
ATOM 8308 O O2    . DT  F 4 17  ? 131.354 139.186 108.055 1.00 218.55 ?  37  DT  F O2    1 
ATOM 8309 N N3    . DT  F 4 17  ? 132.385 137.179 107.875 1.00 218.55 ?  37  DT  F N3    1 
ATOM 8310 C C4    . DT  F 4 17  ? 132.449 135.800 107.950 1.00 218.55 ?  37  DT  F C4    1 
ATOM 8311 O O4    . DT  F 4 17  ? 133.469 135.174 107.679 1.00 218.55 ?  37  DT  F O4    1 
ATOM 8312 C C5    . DT  F 4 17  ? 131.232 135.148 108.371 1.00 218.55 ?  37  DT  F C5    1 
ATOM 8313 C C7    . DT  F 4 17  ? 131.181 133.654 108.486 1.00 218.55 ?  37  DT  F C7    1 
ATOM 8314 C C6    . DT  F 4 17  ? 130.167 135.917 108.648 1.00 218.55 ?  37  DT  F C6    1 
ATOM 8315 P P     . DT  F 4 18  ? 125.371 139.620 107.324 1.00 235.82 ?  38  DT  F P     1 
ATOM 8316 O OP1   . DT  F 4 18  ? 124.373 140.693 107.527 1.00 235.82 ?  38  DT  F OP1   1 
ATOM 8317 O OP2   . DT  F 4 18  ? 124.948 138.330 106.736 1.00 235.82 -1 38  DT  F OP2   1 
ATOM 8318 O "O5'" . DT  F 4 18  ? 126.570 140.200 106.445 1.00 235.82 ?  38  DT  F "O5'" 1 
ATOM 8319 C "C5'" . DT  F 4 18  ? 127.437 141.184 106.996 1.00 235.82 ?  38  DT  F "C5'" 1 
ATOM 8320 C "C4'" . DT  F 4 18  ? 128.494 141.596 105.991 1.00 235.82 ?  38  DT  F "C4'" 1 
ATOM 8321 O "O4'" . DT  F 4 18  ? 129.580 140.629 105.995 1.00 235.82 ?  38  DT  F "O4'" 1 
ATOM 8322 C "C3'" . DT  F 4 18  ? 128.006 141.680 104.546 1.00 235.82 ?  38  DT  F "C3'" 1 
ATOM 8323 O "O3'" . DT  F 4 18  ? 128.579 142.810 103.913 1.00 235.82 ?  38  DT  F "O3'" 1 
ATOM 8324 C "C2'" . DT  F 4 18  ? 128.519 140.377 103.936 1.00 235.82 ?  38  DT  F "C2'" 1 
ATOM 8325 C "C1'" . DT  F 4 18  ? 129.835 140.207 104.674 1.00 235.82 ?  38  DT  F "C1'" 1 
ATOM 8326 N N1    . DT  F 4 18  ? 130.331 138.800 104.713 1.00 235.82 ?  38  DT  F N1    1 
ATOM 8327 C C2    . DT  F 4 18  ? 131.650 138.544 104.414 1.00 235.82 ?  38  DT  F C2    1 
ATOM 8328 O O2    . DT  F 4 18  ? 132.446 139.414 104.111 1.00 235.82 ?  38  DT  F O2    1 
ATOM 8329 N N3    . DT  F 4 18  ? 132.007 137.224 104.483 1.00 235.82 ?  38  DT  F N3    1 
ATOM 8330 C C4    . DT  F 4 18  ? 131.196 136.155 104.814 1.00 235.82 ?  38  DT  F C4    1 
ATOM 8331 O O4    . DT  F 4 18  ? 131.611 135.001 104.848 1.00 235.82 ?  38  DT  F O4    1 
ATOM 8332 C C5    . DT  F 4 18  ? 129.825 136.491 105.117 1.00 235.82 ?  38  DT  F C5    1 
ATOM 8333 C C7    . DT  F 4 18  ? 128.849 135.413 105.488 1.00 235.82 ?  38  DT  F C7    1 
ATOM 8334 C C6    . DT  F 4 18  ? 129.463 137.783 105.053 1.00 235.82 ?  38  DT  F C6    1 
ATOM 8335 P P     . DC  F 4 19  ? 127.840 143.504 102.667 1.00 254.92 ?  39  DC  F P     1 
ATOM 8336 O OP1   . DC  F 4 19  ? 127.383 144.842 103.103 1.00 254.92 ?  39  DC  F OP1   1 
ATOM 8337 O OP2   . DC  F 4 19  ? 126.864 142.535 102.121 1.00 254.92 -1 39  DC  F OP2   1 
ATOM 8338 O "O5'" . DC  F 4 19  ? 129.009 143.682 101.593 1.00 254.92 ?  39  DC  F "O5'" 1 
ATOM 8339 C "C5'" . DC  F 4 19  ? 130.243 144.271 101.984 1.00 254.92 ?  39  DC  F "C5'" 1 
ATOM 8340 C "C4'" . DC  F 4 19  ? 131.368 143.821 101.071 1.00 254.92 ?  39  DC  F "C4'" 1 
ATOM 8341 O "O4'" . DC  F 4 19  ? 131.741 142.453 101.389 1.00 254.92 ?  39  DC  F "O4'" 1 
ATOM 8342 C "C3'" . DC  F 4 19  ? 131.032 143.835 99.579  1.00 254.92 ?  39  DC  F "C3'" 1 
ATOM 8343 O "O3'" . DC  F 4 19  ? 132.125 144.365 98.843  1.00 254.92 ?  39  DC  F "O3'" 1 
ATOM 8344 C "C2'" . DC  F 4 19  ? 130.801 142.359 99.260  1.00 254.92 ?  39  DC  F "C2'" 1 
ATOM 8345 C "C1'" . DC  F 4 19  ? 131.785 141.692 100.204 1.00 254.92 ?  39  DC  F "C1'" 1 
ATOM 8346 N N1    . DC  F 4 19  ? 131.438 140.278 100.536 1.00 254.92 ?  39  DC  F N1    1 
ATOM 8347 C C2    . DC  F 4 19  ? 132.420 139.285 100.448 1.00 254.92 ?  39  DC  F C2    1 
ATOM 8348 O O2    . DC  F 4 19  ? 133.563 139.597 100.093 1.00 254.92 ?  39  DC  F O2    1 
ATOM 8349 N N3    . DC  F 4 19  ? 132.090 138.006 100.755 1.00 254.92 ?  39  DC  F N3    1 
ATOM 8350 C C4    . DC  F 4 19  ? 130.846 137.710 101.134 1.00 254.92 ?  39  DC  F C4    1 
ATOM 8351 N N4    . DC  F 4 19  ? 130.567 136.436 101.427 1.00 254.92 ?  39  DC  F N4    1 
ATOM 8352 C C5    . DC  F 4 19  ? 129.833 138.708 101.228 1.00 254.92 ?  39  DC  F C5    1 
ATOM 8353 C C6    . DC  F 4 19  ? 130.170 139.966 100.923 1.00 254.92 ?  39  DC  F C6    1 
ATOM 8354 P P     . DG  F 4 20  ? 131.924 144.846 97.324  1.00 264.24 ?  40  DG  F P     1 
ATOM 8355 O OP1   . DG  F 4 20  ? 132.566 146.172 97.186  1.00 264.24 ?  40  DG  F OP1   1 
ATOM 8356 O OP2   . DG  F 4 20  ? 130.493 144.682 96.982  1.00 264.24 -1 40  DG  F OP2   1 
ATOM 8357 O "O5'" . DG  F 4 20  ? 132.758 143.779 96.475  1.00 264.24 ?  40  DG  F "O5'" 1 
ATOM 8358 C "C5'" . DG  F 4 20  ? 134.134 143.567 96.764  1.00 264.24 ?  40  DG  F "C5'" 1 
ATOM 8359 C "C4'" . DG  F 4 20  ? 134.593 142.215 96.248  1.00 264.24 ?  40  DG  F "C4'" 1 
ATOM 8360 O "O4'" . DG  F 4 20  ? 133.822 141.164 96.889  1.00 264.24 ?  40  DG  F "O4'" 1 
ATOM 8361 C "C3'" . DG  F 4 20  ? 134.430 142.007 94.741  1.00 264.24 ?  40  DG  F "C3'" 1 
ATOM 8362 O "O3'" . DG  F 4 20  ? 135.587 141.374 94.209  1.00 264.24 ?  40  DG  F "O3'" 1 
ATOM 8363 C "C2'" . DG  F 4 20  ? 133.202 141.105 94.640  1.00 264.24 ?  40  DG  F "C2'" 1 
ATOM 8364 C "C1'" . DG  F 4 20  ? 133.331 140.280 95.909  1.00 264.24 ?  40  DG  F "C1'" 1 
ATOM 8365 N N9    . DG  F 4 20  ? 132.064 139.727 96.376  1.00 264.24 ?  40  DG  F N9    1 
ATOM 8366 C C8    . DG  F 4 20  ? 130.886 140.405 96.572  1.00 264.24 ?  40  DG  F C8    1 
ATOM 8367 N N7    . DG  F 4 20  ? 129.914 139.647 96.998  1.00 264.24 ?  40  DG  F N7    1 
ATOM 8368 C C5    . DG  F 4 20  ? 130.484 138.384 97.087  1.00 264.24 ?  40  DG  F C5    1 
ATOM 8369 C C6    . DG  F 4 20  ? 129.914 137.154 97.491  1.00 264.24 ?  40  DG  F C6    1 
ATOM 8370 O O6    . DG  F 4 20  ? 128.754 136.929 97.863  1.00 264.24 ?  40  DG  F O6    1 
ATOM 8371 N N1    . DG  F 4 20  ? 130.841 136.115 97.435  1.00 264.24 ?  40  DG  F N1    1 
ATOM 8372 C C2    . DG  F 4 20  ? 132.150 136.251 97.039  1.00 264.24 ?  40  DG  F C2    1 
ATOM 8373 N N2    . DG  F 4 20  ? 132.892 135.136 97.050  1.00 264.24 ?  40  DG  F N2    1 
ATOM 8374 N N3    . DG  F 4 20  ? 132.695 137.397 96.659  1.00 264.24 ?  40  DG  F N3    1 
ATOM 8375 C C4    . DG  F 4 20  ? 131.807 138.417 96.707  1.00 264.24 ?  40  DG  F C4    1 
# 
