data_9CFY
# 
_entry.id   9CFY 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CFY         pdb_00009cfy 10.2210/pdb9cfy/pdb 
WWPDB D_1000285440 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-12 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_database_PDB_caveat.id     1 
_database_PDB_caveat.text   'PRO A 22 atom N has a B-factor less than 0.0001.' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CFY 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-27 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB . 9CEI unspecified 
PDB . 9CFI unspecified 
PDB . 9CFM unspecified 
PDB . 9CFO unspecified 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              mwilson13@unl.edu 
_pdbx_contact_author.name_first         Mark 
_pdbx_contact_author.name_last          Wilson 
_pdbx_contact_author.name_mi            A 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-6317-900X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zielinski, K.A.'  1  ? 
'Dolamore, C.'     2  ? 
'Dalton, K.'       3  ? 
'Meisburger, S.P.' 4  ? 
'Smith, N.'        5  ? 
'Termini, T.'      6  ? 
'Henning, R.'      7  ? 
'Srajer, V.'       8  ? 
'Hekstra, D.'      9  ? 
'Pollack, L.'      10 ? 
'Wilson, M.A.'     11 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Resolving DJ-1 Glyoxalase Catalysis Using Mix-and-Inject Serial Crystallography at a Synchrotron.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2024.07.19.604369 
_citation.pdbx_database_id_PubMed   39071394 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zielinski, K.A.' 1  ?                   
primary 'Dolamore, C.'    2  ?                   
primary 'Dalton, K.M.'    3  ?                   
primary 'Smith, N.'       4  ?                   
primary 'Termini, J.'     5  ?                   
primary 'Henning, R.'     6  ?                   
primary 'Srajer, V.'      7  ?                   
primary 'Hekstra, D.R.'   8  ?                   
primary 'Pollack, L.'     9  0000-0002-9366-4396 
primary 'Wilson, M.A.'    10 0000-0001-6317-900X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Parkinson disease protein 7' 20271.391 1   3.1.2.-,3.5.1.-,3.5.1.124 ? ? ? 
2 water   nat water                         18.015    117 ?                         ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
'Maillard deglycase,Oncogene DJ1,Parkinsonism-associated deglycase,Protein DJ-1,DJ-1,Protein/nucleic acid deglycase DJ-1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   yes 
_entity_poly.pdbx_seq_one_letter_code       
;GSHMASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNL
GAQNLSESAAVKEILKEQENRKGLIAAI(A1A7V)AGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGL
ILTSRGPGTSFEFALAIVEALNGKEVAAQVKAPLVLKD
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GSHMASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNL
GAQNLSESAAVKEILKEQENRKGLIAAIXAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRG
PGTSFEFALAIVEALNGKEVAAQVKAPLVLKD
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY   n 
1 2   SER   n 
1 3   HIS   n 
1 4   MET   n 
1 5   ALA   n 
1 6   SER   n 
1 7   LYS   n 
1 8   ARG   n 
1 9   ALA   n 
1 10  LEU   n 
1 11  VAL   n 
1 12  ILE   n 
1 13  LEU   n 
1 14  ALA   n 
1 15  LYS   n 
1 16  GLY   n 
1 17  ALA   n 
1 18  GLU   n 
1 19  GLU   n 
1 20  MET   n 
1 21  GLU   n 
1 22  THR   n 
1 23  VAL   n 
1 24  ILE   n 
1 25  PRO   n 
1 26  VAL   n 
1 27  ASP   n 
1 28  VAL   n 
1 29  MET   n 
1 30  ARG   n 
1 31  ARG   n 
1 32  ALA   n 
1 33  GLY   n 
1 34  ILE   n 
1 35  LYS   n 
1 36  VAL   n 
1 37  THR   n 
1 38  VAL   n 
1 39  ALA   n 
1 40  GLY   n 
1 41  LEU   n 
1 42  ALA   n 
1 43  GLY   n 
1 44  LYS   n 
1 45  ASP   n 
1 46  PRO   n 
1 47  VAL   n 
1 48  GLN   n 
1 49  CYS   n 
1 50  SER   n 
1 51  ARG   n 
1 52  ASP   n 
1 53  VAL   n 
1 54  VAL   n 
1 55  ILE   n 
1 56  CYS   n 
1 57  PRO   n 
1 58  ASP   n 
1 59  ALA   n 
1 60  SER   n 
1 61  LEU   n 
1 62  GLU   n 
1 63  ASP   n 
1 64  ALA   n 
1 65  LYS   n 
1 66  LYS   n 
1 67  GLU   n 
1 68  GLY   n 
1 69  PRO   n 
1 70  TYR   n 
1 71  ASP   n 
1 72  VAL   n 
1 73  VAL   n 
1 74  VAL   n 
1 75  LEU   n 
1 76  PRO   n 
1 77  GLY   n 
1 78  GLY   n 
1 79  ASN   n 
1 80  LEU   n 
1 81  GLY   n 
1 82  ALA   n 
1 83  GLN   n 
1 84  ASN   n 
1 85  LEU   n 
1 86  SER   n 
1 87  GLU   n 
1 88  SER   n 
1 89  ALA   n 
1 90  ALA   n 
1 91  VAL   n 
1 92  LYS   n 
1 93  GLU   n 
1 94  ILE   n 
1 95  LEU   n 
1 96  LYS   n 
1 97  GLU   n 
1 98  GLN   n 
1 99  GLU   n 
1 100 ASN   n 
1 101 ARG   n 
1 102 LYS   n 
1 103 GLY   n 
1 104 LEU   n 
1 105 ILE   n 
1 106 ALA   n 
1 107 ALA   n 
1 108 ILE   n 
1 109 A1A7V n 
1 110 ALA   n 
1 111 GLY   n 
1 112 PRO   n 
1 113 THR   n 
1 114 ALA   n 
1 115 LEU   n 
1 116 LEU   n 
1 117 ALA   n 
1 118 HIS   n 
1 119 GLU   n 
1 120 ILE   n 
1 121 GLY   n 
1 122 PHE   n 
1 123 GLY   n 
1 124 SER   n 
1 125 LYS   n 
1 126 VAL   n 
1 127 THR   n 
1 128 THR   n 
1 129 HIS   n 
1 130 PRO   n 
1 131 LEU   n 
1 132 ALA   n 
1 133 LYS   n 
1 134 ASP   n 
1 135 LYS   n 
1 136 MET   n 
1 137 MET   n 
1 138 ASN   n 
1 139 GLY   n 
1 140 GLY   n 
1 141 HIS   n 
1 142 TYR   n 
1 143 THR   n 
1 144 TYR   n 
1 145 SER   n 
1 146 GLU   n 
1 147 ASN   n 
1 148 ARG   n 
1 149 VAL   n 
1 150 GLU   n 
1 151 LYS   n 
1 152 ASP   n 
1 153 GLY   n 
1 154 LEU   n 
1 155 ILE   n 
1 156 LEU   n 
1 157 THR   n 
1 158 SER   n 
1 159 ARG   n 
1 160 GLY   n 
1 161 PRO   n 
1 162 GLY   n 
1 163 THR   n 
1 164 SER   n 
1 165 PHE   n 
1 166 GLU   n 
1 167 PHE   n 
1 168 ALA   n 
1 169 LEU   n 
1 170 ALA   n 
1 171 ILE   n 
1 172 VAL   n 
1 173 GLU   n 
1 174 ALA   n 
1 175 LEU   n 
1 176 ASN   n 
1 177 GLY   n 
1 178 LYS   n 
1 179 GLU   n 
1 180 VAL   n 
1 181 ALA   n 
1 182 ALA   n 
1 183 GLN   n 
1 184 VAL   n 
1 185 LYS   n 
1 186 ALA   n 
1 187 PRO   n 
1 188 LEU   n 
1 189 VAL   n 
1 190 LEU   n 
1 191 LYS   n 
1 192 ASP   n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   192 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 PARK7 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          PLASMID 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pET15b 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1A7V 'L-peptide linking' n S-lactoyl-L-cysteine 'S-[(2S)-2-hydroxypropanoyl]-L-cysteine' 'C6 H11 N O4 S'  193.221 
ALA   'L-peptide linking' y ALANINE              ?                                        'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE             ?                                        'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE           ?                                        'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'      ?                                        'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE             ?                                        'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE            ?                                        'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'      ?                                        'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE              ?                                        'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE            ?                                        'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER                ?                                        'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE           ?                                        'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE              ?                                        'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE               ?                                        'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE           ?                                        'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE        ?                                        'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE              ?                                        'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE               ?                                        'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE            ?                                        'C4 H9 N O3'     119.119 
TYR   'L-peptide linking' y TYROSINE             ?                                        'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE               ?                                        'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY   1   -2  ?   ?     ?   A . n 
A 1 2   SER   2   -1  ?   ?     ?   A . n 
A 1 3   HIS   3   0   ?   ?     ?   A . n 
A 1 4   MET   4   1   ?   ?     ?   A . n 
A 1 5   ALA   5   2   2   ALA   ALA A . n 
A 1 6   SER   6   3   3   SER   SER A . n 
A 1 7   LYS   7   4   4   LYS   LYS A . n 
A 1 8   ARG   8   5   5   ARG   ARG A . n 
A 1 9   ALA   9   6   6   ALA   ALA A . n 
A 1 10  LEU   10  7   7   LEU   LEU A . n 
A 1 11  VAL   11  8   8   VAL   VAL A . n 
A 1 12  ILE   12  9   9   ILE   ILE A . n 
A 1 13  LEU   13  10  10  LEU   LEU A . n 
A 1 14  ALA   14  11  11  ALA   ALA A . n 
A 1 15  LYS   15  12  12  LYS   LYS A . n 
A 1 16  GLY   16  13  13  GLY   GLY A . n 
A 1 17  ALA   17  14  14  ALA   ALA A . n 
A 1 18  GLU   18  15  15  GLU   GLU A . n 
A 1 19  GLU   19  16  16  GLU   GLU A . n 
A 1 20  MET   20  17  17  MET   MET A . n 
A 1 21  GLU   21  18  18  GLU   GLU A . n 
A 1 22  THR   22  19  19  THR   THR A . n 
A 1 23  VAL   23  20  20  VAL   VAL A . n 
A 1 24  ILE   24  21  21  ILE   ILE A . n 
A 1 25  PRO   25  22  22  PRO   PRO A . n 
A 1 26  VAL   26  23  23  VAL   VAL A . n 
A 1 27  ASP   27  24  24  ASP   ASP A . n 
A 1 28  VAL   28  25  25  VAL   VAL A . n 
A 1 29  MET   29  26  26  MET   MET A . n 
A 1 30  ARG   30  27  27  ARG   ARG A . n 
A 1 31  ARG   31  28  28  ARG   ARG A . n 
A 1 32  ALA   32  29  29  ALA   ALA A . n 
A 1 33  GLY   33  30  30  GLY   GLY A . n 
A 1 34  ILE   34  31  31  ILE   ILE A . n 
A 1 35  LYS   35  32  32  LYS   LYS A . n 
A 1 36  VAL   36  33  33  VAL   VAL A . n 
A 1 37  THR   37  34  34  THR   THR A . n 
A 1 38  VAL   38  35  35  VAL   VAL A . n 
A 1 39  ALA   39  36  36  ALA   ALA A . n 
A 1 40  GLY   40  37  37  GLY   GLY A . n 
A 1 41  LEU   41  38  38  LEU   LEU A . n 
A 1 42  ALA   42  39  39  ALA   ALA A . n 
A 1 43  GLY   43  40  40  GLY   GLY A . n 
A 1 44  LYS   44  41  41  LYS   LYS A . n 
A 1 45  ASP   45  42  42  ASP   ASP A . n 
A 1 46  PRO   46  43  43  PRO   PRO A . n 
A 1 47  VAL   47  44  44  VAL   VAL A . n 
A 1 48  GLN   48  45  45  GLN   GLN A . n 
A 1 49  CYS   49  46  46  CYS   CYS A . n 
A 1 50  SER   50  47  47  SER   SER A . n 
A 1 51  ARG   51  48  48  ARG   ARG A . n 
A 1 52  ASP   52  49  49  ASP   ASP A . n 
A 1 53  VAL   53  50  50  VAL   VAL A . n 
A 1 54  VAL   54  51  51  VAL   VAL A . n 
A 1 55  ILE   55  52  52  ILE   ILE A . n 
A 1 56  CYS   56  53  53  CYS   CYS A . n 
A 1 57  PRO   57  54  54  PRO   PRO A . n 
A 1 58  ASP   58  55  55  ASP   ASP A . n 
A 1 59  ALA   59  56  56  ALA   ALA A . n 
A 1 60  SER   60  57  57  SER   SER A . n 
A 1 61  LEU   61  58  58  LEU   LEU A . n 
A 1 62  GLU   62  59  59  GLU   GLU A . n 
A 1 63  ASP   63  60  60  ASP   ASP A . n 
A 1 64  ALA   64  61  61  ALA   ALA A . n 
A 1 65  LYS   65  62  62  LYS   LYS A . n 
A 1 66  LYS   66  63  63  LYS   LYS A . n 
A 1 67  GLU   67  64  64  GLU   GLU A . n 
A 1 68  GLY   68  65  65  GLY   GLY A . n 
A 1 69  PRO   69  66  66  PRO   PRO A . n 
A 1 70  TYR   70  67  67  TYR   TYR A . n 
A 1 71  ASP   71  68  68  ASP   ASP A . n 
A 1 72  VAL   72  69  69  VAL   VAL A . n 
A 1 73  VAL   73  70  70  VAL   VAL A . n 
A 1 74  VAL   74  71  71  VAL   VAL A . n 
A 1 75  LEU   75  72  72  LEU   LEU A . n 
A 1 76  PRO   76  73  73  PRO   PRO A . n 
A 1 77  GLY   77  74  74  GLY   GLY A . n 
A 1 78  GLY   78  75  75  GLY   GLY A . n 
A 1 79  ASN   79  76  76  ASN   ASN A . n 
A 1 80  LEU   80  77  77  LEU   LEU A . n 
A 1 81  GLY   81  78  78  GLY   GLY A . n 
A 1 82  ALA   82  79  79  ALA   ALA A . n 
A 1 83  GLN   83  80  80  GLN   GLN A . n 
A 1 84  ASN   84  81  81  ASN   ASN A . n 
A 1 85  LEU   85  82  82  LEU   LEU A . n 
A 1 86  SER   86  83  83  SER   SER A . n 
A 1 87  GLU   87  84  84  GLU   GLU A . n 
A 1 88  SER   88  85  85  SER   SER A . n 
A 1 89  ALA   89  86  86  ALA   ALA A . n 
A 1 90  ALA   90  87  87  ALA   ALA A . n 
A 1 91  VAL   91  88  88  VAL   VAL A . n 
A 1 92  LYS   92  89  89  LYS   LYS A . n 
A 1 93  GLU   93  90  90  GLU   GLU A . n 
A 1 94  ILE   94  91  91  ILE   ILE A . n 
A 1 95  LEU   95  92  92  LEU   LEU A . n 
A 1 96  LYS   96  93  93  LYS   LYS A . n 
A 1 97  GLU   97  94  94  GLU   GLU A . n 
A 1 98  GLN   98  95  95  GLN   GLN A . n 
A 1 99  GLU   99  96  96  GLU   GLU A . n 
A 1 100 ASN   100 97  97  ASN   ASN A . n 
A 1 101 ARG   101 98  98  ARG   ARG A . n 
A 1 102 LYS   102 99  99  LYS   LYS A . n 
A 1 103 GLY   103 100 100 GLY   GLY A . n 
A 1 104 LEU   104 101 101 LEU   LEU A . n 
A 1 105 ILE   105 102 102 ILE   ILE A . n 
A 1 106 ALA   106 103 103 ALA   ALA A . n 
A 1 107 ALA   107 104 104 ALA   ALA A . n 
A 1 108 ILE   108 105 105 ILE   ILE A . n 
A 1 109 A1A7V 109 106 106 A1A7V CYS A . n 
A 1 110 ALA   110 107 107 ALA   ALA A . n 
A 1 111 GLY   111 108 108 GLY   GLY A . n 
A 1 112 PRO   112 109 109 PRO   PRO A . n 
A 1 113 THR   113 110 110 THR   THR A . n 
A 1 114 ALA   114 111 111 ALA   ALA A . n 
A 1 115 LEU   115 112 112 LEU   LEU A . n 
A 1 116 LEU   116 113 113 LEU   LEU A . n 
A 1 117 ALA   117 114 114 ALA   ALA A . n 
A 1 118 HIS   118 115 115 HIS   HIS A . n 
A 1 119 GLU   119 116 116 GLU   GLU A . n 
A 1 120 ILE   120 117 117 ILE   ILE A . n 
A 1 121 GLY   121 118 118 GLY   GLY A . n 
A 1 122 PHE   122 119 119 PHE   PHE A . n 
A 1 123 GLY   123 120 120 GLY   GLY A . n 
A 1 124 SER   124 121 121 SER   SER A . n 
A 1 125 LYS   125 122 122 LYS   LYS A . n 
A 1 126 VAL   126 123 123 VAL   VAL A . n 
A 1 127 THR   127 124 124 THR   THR A . n 
A 1 128 THR   128 125 125 THR   THR A . n 
A 1 129 HIS   129 126 126 HIS   HIS A . n 
A 1 130 PRO   130 127 127 PRO   PRO A . n 
A 1 131 LEU   131 128 128 LEU   LEU A . n 
A 1 132 ALA   132 129 129 ALA   ALA A . n 
A 1 133 LYS   133 130 130 LYS   LYS A . n 
A 1 134 ASP   134 131 131 ASP   ASP A . n 
A 1 135 LYS   135 132 132 LYS   LYS A . n 
A 1 136 MET   136 133 133 MET   MET A . n 
A 1 137 MET   137 134 134 MET   MET A . n 
A 1 138 ASN   138 135 135 ASN   ASN A . n 
A 1 139 GLY   139 136 136 GLY   GLY A . n 
A 1 140 GLY   140 137 137 GLY   GLY A . n 
A 1 141 HIS   141 138 138 HIS   HIS A . n 
A 1 142 TYR   142 139 139 TYR   TYR A . n 
A 1 143 THR   143 140 140 THR   THR A . n 
A 1 144 TYR   144 141 141 TYR   TYR A . n 
A 1 145 SER   145 142 142 SER   SER A . n 
A 1 146 GLU   146 143 143 GLU   GLU A . n 
A 1 147 ASN   147 144 144 ASN   ASN A . n 
A 1 148 ARG   148 145 145 ARG   ARG A . n 
A 1 149 VAL   149 146 146 VAL   VAL A . n 
A 1 150 GLU   150 147 147 GLU   GLU A . n 
A 1 151 LYS   151 148 148 LYS   LYS A . n 
A 1 152 ASP   152 149 149 ASP   ASP A . n 
A 1 153 GLY   153 150 150 GLY   GLY A . n 
A 1 154 LEU   154 151 151 LEU   LEU A . n 
A 1 155 ILE   155 152 152 ILE   ILE A . n 
A 1 156 LEU   156 153 153 LEU   LEU A . n 
A 1 157 THR   157 154 154 THR   THR A . n 
A 1 158 SER   158 155 155 SER   SER A . n 
A 1 159 ARG   159 156 156 ARG   ARG A . n 
A 1 160 GLY   160 157 157 GLY   GLY A . n 
A 1 161 PRO   161 158 158 PRO   PRO A . n 
A 1 162 GLY   162 159 159 GLY   GLY A . n 
A 1 163 THR   163 160 160 THR   THR A . n 
A 1 164 SER   164 161 161 SER   SER A . n 
A 1 165 PHE   165 162 162 PHE   PHE A . n 
A 1 166 GLU   166 163 163 GLU   GLU A . n 
A 1 167 PHE   167 164 164 PHE   PHE A . n 
A 1 168 ALA   168 165 165 ALA   ALA A . n 
A 1 169 LEU   169 166 166 LEU   LEU A . n 
A 1 170 ALA   170 167 167 ALA   ALA A . n 
A 1 171 ILE   171 168 168 ILE   ILE A . n 
A 1 172 VAL   172 169 169 VAL   VAL A . n 
A 1 173 GLU   173 170 170 GLU   GLU A . n 
A 1 174 ALA   174 171 171 ALA   ALA A . n 
A 1 175 LEU   175 172 172 LEU   LEU A . n 
A 1 176 ASN   176 173 173 ASN   ASN A . n 
A 1 177 GLY   177 174 174 GLY   GLY A . n 
A 1 178 LYS   178 175 175 LYS   LYS A . n 
A 1 179 GLU   179 176 176 GLU   GLU A . n 
A 1 180 VAL   180 177 177 VAL   VAL A . n 
A 1 181 ALA   181 178 178 ALA   ALA A . n 
A 1 182 ALA   182 179 179 ALA   ALA A . n 
A 1 183 GLN   183 180 180 GLN   GLN A . n 
A 1 184 VAL   184 181 181 VAL   VAL A . n 
A 1 185 LYS   185 182 182 LYS   LYS A . n 
A 1 186 ALA   186 183 183 ALA   ALA A . n 
A 1 187 PRO   187 184 184 PRO   PRO A . n 
A 1 188 LEU   188 185 185 LEU   LEU A . n 
A 1 189 VAL   189 186 186 VAL   VAL A . n 
A 1 190 LEU   190 187 187 LEU   LEU A . n 
A 1 191 LYS   191 188 188 LYS   LYS A . n 
A 1 192 ASP   192 189 189 ASP   ASP A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1A7V 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1A7V 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 HOH 1   301 70  HOH HOH A . 
B 2 HOH 2   302 89  HOH HOH A . 
B 2 HOH 3   303 23  HOH HOH A . 
B 2 HOH 4   304 105 HOH HOH A . 
B 2 HOH 5   305 25  HOH HOH A . 
B 2 HOH 6   306 67  HOH HOH A . 
B 2 HOH 7   307 61  HOH HOH A . 
B 2 HOH 8   308 5   HOH HOH A . 
B 2 HOH 9   309 28  HOH HOH A . 
B 2 HOH 10  310 102 HOH HOH A . 
B 2 HOH 11  311 9   HOH HOH A . 
B 2 HOH 12  312 74  HOH HOH A . 
B 2 HOH 13  313 11  HOH HOH A . 
B 2 HOH 14  314 4   HOH HOH A . 
B 2 HOH 15  315 27  HOH HOH A . 
B 2 HOH 16  316 29  HOH HOH A . 
B 2 HOH 17  317 93  HOH HOH A . 
B 2 HOH 18  318 75  HOH HOH A . 
B 2 HOH 19  319 36  HOH HOH A . 
B 2 HOH 20  320 43  HOH HOH A . 
B 2 HOH 21  321 35  HOH HOH A . 
B 2 HOH 22  322 69  HOH HOH A . 
B 2 HOH 23  323 10  HOH HOH A . 
B 2 HOH 24  324 19  HOH HOH A . 
B 2 HOH 25  325 21  HOH HOH A . 
B 2 HOH 26  326 101 HOH HOH A . 
B 2 HOH 27  327 41  HOH HOH A . 
B 2 HOH 28  328 98  HOH HOH A . 
B 2 HOH 29  329 6   HOH HOH A . 
B 2 HOH 30  330 49  HOH HOH A . 
B 2 HOH 31  331 3   HOH HOH A . 
B 2 HOH 32  332 32  HOH HOH A . 
B 2 HOH 33  333 44  HOH HOH A . 
B 2 HOH 34  334 60  HOH HOH A . 
B 2 HOH 35  335 15  HOH HOH A . 
B 2 HOH 36  336 7   HOH HOH A . 
B 2 HOH 37  337 1   HOH HOH A . 
B 2 HOH 38  338 26  HOH HOH A . 
B 2 HOH 39  339 47  HOH HOH A . 
B 2 HOH 40  340 90  HOH HOH A . 
B 2 HOH 41  341 30  HOH HOH A . 
B 2 HOH 42  342 57  HOH HOH A . 
B 2 HOH 43  343 116 HOH HOH A . 
B 2 HOH 44  344 34  HOH HOH A . 
B 2 HOH 45  345 68  HOH HOH A . 
B 2 HOH 46  346 54  HOH HOH A . 
B 2 HOH 47  347 62  HOH HOH A . 
B 2 HOH 48  348 117 HOH HOH A . 
B 2 HOH 49  349 52  HOH HOH A . 
B 2 HOH 50  350 14  HOH HOH A . 
B 2 HOH 51  351 100 HOH HOH A . 
B 2 HOH 52  352 8   HOH HOH A . 
B 2 HOH 53  353 109 HOH HOH A . 
B 2 HOH 54  354 76  HOH HOH A . 
B 2 HOH 55  355 2   HOH HOH A . 
B 2 HOH 56  356 33  HOH HOH A . 
B 2 HOH 57  357 85  HOH HOH A . 
B 2 HOH 58  358 87  HOH HOH A . 
B 2 HOH 59  359 113 HOH HOH A . 
B 2 HOH 60  360 13  HOH HOH A . 
B 2 HOH 61  361 39  HOH HOH A . 
B 2 HOH 62  362 56  HOH HOH A . 
B 2 HOH 63  363 86  HOH HOH A . 
B 2 HOH 64  364 92  HOH HOH A . 
B 2 HOH 65  365 78  HOH HOH A . 
B 2 HOH 66  366 22  HOH HOH A . 
B 2 HOH 67  367 64  HOH HOH A . 
B 2 HOH 68  368 24  HOH HOH A . 
B 2 HOH 69  369 73  HOH HOH A . 
B 2 HOH 70  370 51  HOH HOH A . 
B 2 HOH 71  371 84  HOH HOH A . 
B 2 HOH 72  372 40  HOH HOH A . 
B 2 HOH 73  373 110 HOH HOH A . 
B 2 HOH 74  374 31  HOH HOH A . 
B 2 HOH 75  375 16  HOH HOH A . 
B 2 HOH 76  376 12  HOH HOH A . 
B 2 HOH 77  377 53  HOH HOH A . 
B 2 HOH 78  378 20  HOH HOH A . 
B 2 HOH 79  379 65  HOH HOH A . 
B 2 HOH 80  380 97  HOH HOH A . 
B 2 HOH 81  381 59  HOH HOH A . 
B 2 HOH 82  382 17  HOH HOH A . 
B 2 HOH 83  383 82  HOH HOH A . 
B 2 HOH 84  384 99  HOH HOH A . 
B 2 HOH 85  385 111 HOH HOH A . 
B 2 HOH 86  386 66  HOH HOH A . 
B 2 HOH 87  387 77  HOH HOH A . 
B 2 HOH 88  388 115 HOH HOH A . 
B 2 HOH 89  389 104 HOH HOH A . 
B 2 HOH 90  390 96  HOH HOH A . 
B 2 HOH 91  391 55  HOH HOH A . 
B 2 HOH 92  392 80  HOH HOH A . 
B 2 HOH 93  393 50  HOH HOH A . 
B 2 HOH 94  394 58  HOH HOH A . 
B 2 HOH 95  395 37  HOH HOH A . 
B 2 HOH 96  396 112 HOH HOH A . 
B 2 HOH 97  397 107 HOH HOH A . 
B 2 HOH 98  398 46  HOH HOH A . 
B 2 HOH 99  399 45  HOH HOH A . 
B 2 HOH 100 400 18  HOH HOH A . 
B 2 HOH 101 401 95  HOH HOH A . 
B 2 HOH 102 402 103 HOH HOH A . 
B 2 HOH 103 403 38  HOH HOH A . 
B 2 HOH 104 404 108 HOH HOH A . 
B 2 HOH 105 405 83  HOH HOH A . 
B 2 HOH 106 406 48  HOH HOH A . 
B 2 HOH 107 407 72  HOH HOH A . 
B 2 HOH 108 408 88  HOH HOH A . 
B 2 HOH 109 409 63  HOH HOH A . 
B 2 HOH 110 410 114 HOH HOH A . 
B 2 HOH 111 411 106 HOH HOH A . 
B 2 HOH 112 412 91  HOH HOH A . 
B 2 HOH 113 413 42  HOH HOH A . 
B 2 HOH 114 414 79  HOH HOH A . 
B 2 HOH 115 415 71  HOH HOH A . 
B 2 HOH 116 416 81  HOH HOH A . 
B 2 HOH 117 417 94  HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX       ? ? ? 1.20.1_4487 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? Precognition ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? careless     ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX       ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CFY 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     76.030 
_cell.length_a_esd                 ? 
_cell.length_b                     76.030 
_cell.length_b_esd                 ? 
_cell.length_c                     76.140 
_cell.length_c_esd                 ? 
_cell.volume                       381165.412 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CFY 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                152 
_symmetry.space_group_name_Hall            
;P 31 2"
;
_symmetry.space_group_name_H-M             'P 31 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CFY 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.15 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          60.89 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'BATCH MODE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '100 mM HEPES pH=7.5, 200 mM NaCl, and 15% PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     293 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   Y 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'RAYONIX MX340-HS' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-11-13 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   L 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             LAUE 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
loop_
_diffrn_radiation_wavelength.id 
_diffrn_radiation_wavelength.wavelength 
_diffrn_radiation_wavelength.wt 
1 1.240 1.0 
2 1.016 1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 14-ID-B' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.240-1.016 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   14-ID-B 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          -0.23 
_reflns.entry_id                                       9CFY 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.77 
_reflns.d_resolution_low                               65.84 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     25225 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.86 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                65.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          20.43 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.99 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.77 
_reflns_shell.d_res_low                                     1.83 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.39 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2460 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               22.0 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.35 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.88 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               15.78 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9CFY 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.77 
_refine.ls_d_res_low                             65.84 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     25192 
_refine.ls_number_reflns_R_free                  1145 
_refine.ls_number_reflns_R_work                  24047 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.87 
_refine.ls_percent_reflns_R_free                 4.55 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2021 
_refine.ls_R_factor_R_free                       0.2296 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2008 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.74 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'FOURIER SYNTHESIS' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 22.3616 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2701 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.77 
_refine_hist.d_res_low                        65.84 
_refine_hist.number_atoms_solvent             117 
_refine_hist.number_atoms_total               1505 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1383 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         5 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0092  ? 1465 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.9335  ? 1988 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0567  ? 234  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0068  ? 262  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 13.2339 ? 567  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.77 1.85  . . 155 2945 99.90  . . . . 0.3295 . . . . . . . . . . . 0.3491 
'X-RAY DIFFRACTION' 1.85 1.95  . . 133 2969 100.00 . . . . 0.3047 . . . . . . . . . . . 0.3353 
'X-RAY DIFFRACTION' 1.95 2.07  . . 157 2949 100.00 . . . . 0.2358 . . . . . . . . . . . 0.2653 
'X-RAY DIFFRACTION' 2.07 2.23  . . 149 2976 100.00 . . . . 0.2042 . . . . . . . . . . . 0.1995 
'X-RAY DIFFRACTION' 2.23 2.45  . . 129 3036 100.00 . . . . 0.1503 . . . . . . . . . . . 0.1930 
'X-RAY DIFFRACTION' 2.45 2.81  . . 137 2994 100.00 . . . . 0.1436 . . . . . . . . . . . 0.1776 
'X-RAY DIFFRACTION' 2.81 3.54  . . 153 3021 99.91  . . . . 0.1439 . . . . . . . . . . . 0.1647 
'X-RAY DIFFRACTION' 3.54 65.84 . . 132 3157 99.16  . . . . 0.1389 . . . . . . . . . . . 0.1786 
# 
_struct.entry_id                     9CFY 
_struct.title                        'Human DJ-1, 15 sec mixing with methylglyoxal, pink beam time-resolved serial crystallography' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CFY 
_struct_keywords.text            
'glutathione-independent glyoxalase, mix-and-inject serial crystallography, Laue diffraction, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    PARK7_HUMAN 
_struct_ref.pdbx_db_accession          Q99497 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTVAGLAGKDPVQCSRDVVICPDASLEDAKKEGPYDVVVLPGGNLGAQ
NLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGSKVTTHPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGT
SFEFALAIVEALNGKEVAAQVKAPLVLKD
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9CFY 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 4 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 192 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q99497 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  189 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       189 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9CFY GLY A 1 ? UNP Q99497 ? ? 'expression tag' -2 1 
1 9CFY SER A 2 ? UNP Q99497 ? ? 'expression tag' -1 2 
1 9CFY HIS A 3 ? UNP Q99497 ? ? 'expression tag' 0  3 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 2810  ? 
1 MORE         -17   ? 
1 'SSA (A^2)'  15160 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1,2 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z         1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000  
2 'crystal symmetry operation' 5_555 x-y,-y,-z+2/3 1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 50.7600000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLU A 18  ? ALA A 32  ? GLU A 15  ALA A 29  1 ? 15 
HELX_P HELX_P2  AA2 LEU A 61  ? LYS A 66  ? LEU A 58  LYS A 63  1 ? 6  
HELX_P HELX_P3  AA3 GLY A 78  ? SER A 88  ? GLY A 75  SER A 85  1 ? 11 
HELX_P HELX_P4  AA4 SER A 88  ? ARG A 101 ? SER A 85  ARG A 98  1 ? 14 
HELX_P HELX_P5  AA5 PRO A 112 ? HIS A 118 ? PRO A 109 HIS A 115 1 ? 7  
HELX_P HELX_P6  AA6 HIS A 129 ? LEU A 131 ? HIS A 126 LEU A 128 5 ? 3  
HELX_P HELX_P7  AA7 ALA A 132 ? MET A 137 ? ALA A 129 MET A 134 1 ? 6  
HELX_P HELX_P8  AA8 GLY A 160 ? GLY A 162 ? GLY A 157 GLY A 159 5 ? 3  
HELX_P HELX_P9  AA9 THR A 163 ? GLY A 177 ? THR A 160 GLY A 174 1 ? 15 
HELX_P HELX_P10 AB1 GLY A 177 ? ALA A 186 ? GLY A 174 ALA A 183 1 ? 10 
HELX_P HELX_P11 AB2 PRO A 187 ? VAL A 189 ? PRO A 184 VAL A 186 5 ? 3  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? A ILE   108 C ? ? ? 1_555 A A1A7V 109 N ? ? A ILE   105 A A1A7V 106 1_555 ? ? ? ? ? ? ? 1.333 ? ? 
covale2 covale both ? A A1A7V 109 C ? ? ? 1_555 A ALA   110 N ? ? A A1A7V 106 A ALA   107 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      A1A7V 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       109 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     . 
_pdbx_modification_feature.modified_residue_label_asym_id     . 
_pdbx_modification_feature.modified_residue_label_seq_id      . 
_pdbx_modification_feature.modified_residue_label_alt_id      . 
_pdbx_modification_feature.auth_comp_id                       A1A7V 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        106 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      . 
_pdbx_modification_feature.modified_residue_auth_asym_id      . 
_pdbx_modification_feature.modified_residue_auth_seq_id       . 
_pdbx_modification_feature.modified_residue_PDB_ins_code      . 
_pdbx_modification_feature.modified_residue_symmetry          . 
_pdbx_modification_feature.comp_id_linking_atom               . 
_pdbx_modification_feature.modified_residue_id_linking_atom   . 
_pdbx_modification_feature.modified_residue_id                CYS 
_pdbx_modification_feature.ref_pcm_id                         1 
_pdbx_modification_feature.ref_comp_id                        A1A7V 
_pdbx_modification_feature.type                               Lactoylation 
_pdbx_modification_feature.category                           'Named protein modification' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          GLY 
_struct_mon_prot_cis.label_seq_id           68 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           GLY 
_struct_mon_prot_cis.auth_seq_id            65 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    69 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     66 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -1.41 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 59  ? SER A 60  ? ALA A 56  SER A 57  
AA1 2 LYS A 35  ? GLY A 40  ? LYS A 32  GLY A 37  
AA1 3 ARG A 8   ? LEU A 13  ? ARG A 5   LEU A 10  
AA1 4 VAL A 72  ? LEU A 75  ? VAL A 69  LEU A 72  
AA1 5 LEU A 104 ? ILE A 108 ? LEU A 101 ILE A 105 
AA1 6 ILE A 155 ? SER A 158 ? ILE A 152 SER A 155 
AA1 7 VAL A 149 ? ASP A 152 ? VAL A 146 ASP A 149 
AA2 1 VAL A 47  ? GLN A 48  ? VAL A 44  GLN A 45  
AA2 2 VAL A 54  ? ILE A 55  ? VAL A 51  ILE A 52  
AA3 1 LYS A 125 ? VAL A 126 ? LYS A 122 VAL A 123 
AA3 2 THR A 143 ? TYR A 144 ? THR A 140 TYR A 141 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ALA A 59  ? O ALA A 56  N GLY A 40  ? N GLY A 37  
AA1 2 3 O ALA A 39  ? O ALA A 36  N LEU A 13  ? N LEU A 10  
AA1 3 4 N LEU A 10  ? N LEU A 7   O VAL A 74  ? O VAL A 71  
AA1 4 5 N VAL A 73  ? N VAL A 70  O ALA A 106 ? O ALA A 103 
AA1 5 6 N ILE A 105 ? N ILE A 102 O LEU A 156 ? O LEU A 153 
AA1 6 7 O THR A 157 ? O THR A 154 N GLU A 150 ? N GLU A 147 
AA2 1 2 N VAL A 47  ? N VAL A 44  O ILE A 55  ? O ILE A 52  
AA3 1 2 N VAL A 126 ? N VAL A 123 O THR A 143 ? O THR A 140 
# 
_pdbx_entry_details.entry_id                   9CFY 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_torsion.id              1 
_pdbx_validate_torsion.PDB_model_num   1 
_pdbx_validate_torsion.auth_comp_id    A1A7V 
_pdbx_validate_torsion.auth_asym_id    A 
_pdbx_validate_torsion.auth_seq_id     106 
_pdbx_validate_torsion.PDB_ins_code    ? 
_pdbx_validate_torsion.label_alt_id    ? 
_pdbx_validate_torsion.phi             74.93 
_pdbx_validate_torsion.psi             -105.84 
# 
_pdbx_struct_mod_residue.id               1 
_pdbx_struct_mod_residue.label_asym_id    A 
_pdbx_struct_mod_residue.label_comp_id    A1A7V 
_pdbx_struct_mod_residue.label_seq_id     109 
_pdbx_struct_mod_residue.auth_asym_id     A 
_pdbx_struct_mod_residue.auth_comp_id     A1A7V 
_pdbx_struct_mod_residue.auth_seq_id      106 
_pdbx_struct_mod_residue.PDB_ins_code     ? 
_pdbx_struct_mod_residue.parent_comp_id   CYS 
_pdbx_struct_mod_residue.details          'modified residue' 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+1/3   
3 -x+y,-x,z+2/3  
4 x-y,-y,-z+2/3  
5 -x,-x+y,-z+1/3 
6 y,x,-z         
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A GLY -2 ? A GLY 1 
2 1 Y 1 A SER -1 ? A SER 2 
3 1 Y 1 A HIS 0  ? A HIS 3 
4 1 Y 1 A MET 1  ? A MET 4 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1A7V C    C N N 1   
A1A7V N    N N N 2   
A1A7V O    O N N 3   
A1A7V CA   C N R 4   
A1A7V CB   C N N 5   
A1A7V SG   S N N 6   
A1A7V C1   C N N 7   
A1A7V O1   O N N 8   
A1A7V C2   C N S 9   
A1A7V O2   O N N 10  
A1A7V C3   C N N 11  
A1A7V H    H N N 12  
A1A7V H2   H N N 13  
A1A7V HA   H N N 14  
A1A7V HB3  H N N 15  
A1A7V HB2  H N N 16  
A1A7V H20  H N N 17  
A1A7V HO2  H N N 18  
A1A7V H3B  H N N 19  
A1A7V H3A  H N N 20  
A1A7V H3   H N N 21  
A1A7V OXT  O N N 22  
A1A7V HXT  H N N 23  
ALA   N    N N N 24  
ALA   CA   C N S 25  
ALA   C    C N N 26  
ALA   O    O N N 27  
ALA   CB   C N N 28  
ALA   OXT  O N N 29  
ALA   H    H N N 30  
ALA   H2   H N N 31  
ALA   HA   H N N 32  
ALA   HB1  H N N 33  
ALA   HB2  H N N 34  
ALA   HB3  H N N 35  
ALA   HXT  H N N 36  
ARG   N    N N N 37  
ARG   CA   C N S 38  
ARG   C    C N N 39  
ARG   O    O N N 40  
ARG   CB   C N N 41  
ARG   CG   C N N 42  
ARG   CD   C N N 43  
ARG   NE   N N N 44  
ARG   CZ   C N N 45  
ARG   NH1  N N N 46  
ARG   NH2  N N N 47  
ARG   OXT  O N N 48  
ARG   H    H N N 49  
ARG   H2   H N N 50  
ARG   HA   H N N 51  
ARG   HB2  H N N 52  
ARG   HB3  H N N 53  
ARG   HG2  H N N 54  
ARG   HG3  H N N 55  
ARG   HD2  H N N 56  
ARG   HD3  H N N 57  
ARG   HE   H N N 58  
ARG   HH11 H N N 59  
ARG   HH12 H N N 60  
ARG   HH21 H N N 61  
ARG   HH22 H N N 62  
ARG   HXT  H N N 63  
ASN   N    N N N 64  
ASN   CA   C N S 65  
ASN   C    C N N 66  
ASN   O    O N N 67  
ASN   CB   C N N 68  
ASN   CG   C N N 69  
ASN   OD1  O N N 70  
ASN   ND2  N N N 71  
ASN   OXT  O N N 72  
ASN   H    H N N 73  
ASN   H2   H N N 74  
ASN   HA   H N N 75  
ASN   HB2  H N N 76  
ASN   HB3  H N N 77  
ASN   HD21 H N N 78  
ASN   HD22 H N N 79  
ASN   HXT  H N N 80  
ASP   N    N N N 81  
ASP   CA   C N S 82  
ASP   C    C N N 83  
ASP   O    O N N 84  
ASP   CB   C N N 85  
ASP   CG   C N N 86  
ASP   OD1  O N N 87  
ASP   OD2  O N N 88  
ASP   OXT  O N N 89  
ASP   H    H N N 90  
ASP   H2   H N N 91  
ASP   HA   H N N 92  
ASP   HB2  H N N 93  
ASP   HB3  H N N 94  
ASP   HD2  H N N 95  
ASP   HXT  H N N 96  
CYS   N    N N N 97  
CYS   CA   C N R 98  
CYS   C    C N N 99  
CYS   O    O N N 100 
CYS   CB   C N N 101 
CYS   SG   S N N 102 
CYS   OXT  O N N 103 
CYS   H    H N N 104 
CYS   H2   H N N 105 
CYS   HA   H N N 106 
CYS   HB2  H N N 107 
CYS   HB3  H N N 108 
CYS   HG   H N N 109 
CYS   HXT  H N N 110 
GLN   N    N N N 111 
GLN   CA   C N S 112 
GLN   C    C N N 113 
GLN   O    O N N 114 
GLN   CB   C N N 115 
GLN   CG   C N N 116 
GLN   CD   C N N 117 
GLN   OE1  O N N 118 
GLN   NE2  N N N 119 
GLN   OXT  O N N 120 
GLN   H    H N N 121 
GLN   H2   H N N 122 
GLN   HA   H N N 123 
GLN   HB2  H N N 124 
GLN   HB3  H N N 125 
GLN   HG2  H N N 126 
GLN   HG3  H N N 127 
GLN   HE21 H N N 128 
GLN   HE22 H N N 129 
GLN   HXT  H N N 130 
GLU   N    N N N 131 
GLU   CA   C N S 132 
GLU   C    C N N 133 
GLU   O    O N N 134 
GLU   CB   C N N 135 
GLU   CG   C N N 136 
GLU   CD   C N N 137 
GLU   OE1  O N N 138 
GLU   OE2  O N N 139 
GLU   OXT  O N N 140 
GLU   H    H N N 141 
GLU   H2   H N N 142 
GLU   HA   H N N 143 
GLU   HB2  H N N 144 
GLU   HB3  H N N 145 
GLU   HG2  H N N 146 
GLU   HG3  H N N 147 
GLU   HE2  H N N 148 
GLU   HXT  H N N 149 
GLY   N    N N N 150 
GLY   CA   C N N 151 
GLY   C    C N N 152 
GLY   O    O N N 153 
GLY   OXT  O N N 154 
GLY   H    H N N 155 
GLY   H2   H N N 156 
GLY   HA2  H N N 157 
GLY   HA3  H N N 158 
GLY   HXT  H N N 159 
HIS   N    N N N 160 
HIS   CA   C N S 161 
HIS   C    C N N 162 
HIS   O    O N N 163 
HIS   CB   C N N 164 
HIS   CG   C Y N 165 
HIS   ND1  N Y N 166 
HIS   CD2  C Y N 167 
HIS   CE1  C Y N 168 
HIS   NE2  N Y N 169 
HIS   OXT  O N N 170 
HIS   H    H N N 171 
HIS   H2   H N N 172 
HIS   HA   H N N 173 
HIS   HB2  H N N 174 
HIS   HB3  H N N 175 
HIS   HD1  H N N 176 
HIS   HD2  H N N 177 
HIS   HE1  H N N 178 
HIS   HE2  H N N 179 
HIS   HXT  H N N 180 
HOH   O    O N N 181 
HOH   H1   H N N 182 
HOH   H2   H N N 183 
ILE   N    N N N 184 
ILE   CA   C N S 185 
ILE   C    C N N 186 
ILE   O    O N N 187 
ILE   CB   C N S 188 
ILE   CG1  C N N 189 
ILE   CG2  C N N 190 
ILE   CD1  C N N 191 
ILE   OXT  O N N 192 
ILE   H    H N N 193 
ILE   H2   H N N 194 
ILE   HA   H N N 195 
ILE   HB   H N N 196 
ILE   HG12 H N N 197 
ILE   HG13 H N N 198 
ILE   HG21 H N N 199 
ILE   HG22 H N N 200 
ILE   HG23 H N N 201 
ILE   HD11 H N N 202 
ILE   HD12 H N N 203 
ILE   HD13 H N N 204 
ILE   HXT  H N N 205 
LEU   N    N N N 206 
LEU   CA   C N S 207 
LEU   C    C N N 208 
LEU   O    O N N 209 
LEU   CB   C N N 210 
LEU   CG   C N N 211 
LEU   CD1  C N N 212 
LEU   CD2  C N N 213 
LEU   OXT  O N N 214 
LEU   H    H N N 215 
LEU   H2   H N N 216 
LEU   HA   H N N 217 
LEU   HB2  H N N 218 
LEU   HB3  H N N 219 
LEU   HG   H N N 220 
LEU   HD11 H N N 221 
LEU   HD12 H N N 222 
LEU   HD13 H N N 223 
LEU   HD21 H N N 224 
LEU   HD22 H N N 225 
LEU   HD23 H N N 226 
LEU   HXT  H N N 227 
LYS   N    N N N 228 
LYS   CA   C N S 229 
LYS   C    C N N 230 
LYS   O    O N N 231 
LYS   CB   C N N 232 
LYS   CG   C N N 233 
LYS   CD   C N N 234 
LYS   CE   C N N 235 
LYS   NZ   N N N 236 
LYS   OXT  O N N 237 
LYS   H    H N N 238 
LYS   H2   H N N 239 
LYS   HA   H N N 240 
LYS   HB2  H N N 241 
LYS   HB3  H N N 242 
LYS   HG2  H N N 243 
LYS   HG3  H N N 244 
LYS   HD2  H N N 245 
LYS   HD3  H N N 246 
LYS   HE2  H N N 247 
LYS   HE3  H N N 248 
LYS   HZ1  H N N 249 
LYS   HZ2  H N N 250 
LYS   HZ3  H N N 251 
LYS   HXT  H N N 252 
MET   N    N N N 253 
MET   CA   C N S 254 
MET   C    C N N 255 
MET   O    O N N 256 
MET   CB   C N N 257 
MET   CG   C N N 258 
MET   SD   S N N 259 
MET   CE   C N N 260 
MET   OXT  O N N 261 
MET   H    H N N 262 
MET   H2   H N N 263 
MET   HA   H N N 264 
MET   HB2  H N N 265 
MET   HB3  H N N 266 
MET   HG2  H N N 267 
MET   HG3  H N N 268 
MET   HE1  H N N 269 
MET   HE2  H N N 270 
MET   HE3  H N N 271 
MET   HXT  H N N 272 
PHE   N    N N N 273 
PHE   CA   C N S 274 
PHE   C    C N N 275 
PHE   O    O N N 276 
PHE   CB   C N N 277 
PHE   CG   C Y N 278 
PHE   CD1  C Y N 279 
PHE   CD2  C Y N 280 
PHE   CE1  C Y N 281 
PHE   CE2  C Y N 282 
PHE   CZ   C Y N 283 
PHE   OXT  O N N 284 
PHE   H    H N N 285 
PHE   H2   H N N 286 
PHE   HA   H N N 287 
PHE   HB2  H N N 288 
PHE   HB3  H N N 289 
PHE   HD1  H N N 290 
PHE   HD2  H N N 291 
PHE   HE1  H N N 292 
PHE   HE2  H N N 293 
PHE   HZ   H N N 294 
PHE   HXT  H N N 295 
PRO   N    N N N 296 
PRO   CA   C N S 297 
PRO   C    C N N 298 
PRO   O    O N N 299 
PRO   CB   C N N 300 
PRO   CG   C N N 301 
PRO   CD   C N N 302 
PRO   OXT  O N N 303 
PRO   H    H N N 304 
PRO   HA   H N N 305 
PRO   HB2  H N N 306 
PRO   HB3  H N N 307 
PRO   HG2  H N N 308 
PRO   HG3  H N N 309 
PRO   HD2  H N N 310 
PRO   HD3  H N N 311 
PRO   HXT  H N N 312 
SER   N    N N N 313 
SER   CA   C N S 314 
SER   C    C N N 315 
SER   O    O N N 316 
SER   CB   C N N 317 
SER   OG   O N N 318 
SER   OXT  O N N 319 
SER   H    H N N 320 
SER   H2   H N N 321 
SER   HA   H N N 322 
SER   HB2  H N N 323 
SER   HB3  H N N 324 
SER   HG   H N N 325 
SER   HXT  H N N 326 
THR   N    N N N 327 
THR   CA   C N S 328 
THR   C    C N N 329 
THR   O    O N N 330 
THR   CB   C N R 331 
THR   OG1  O N N 332 
THR   CG2  C N N 333 
THR   OXT  O N N 334 
THR   H    H N N 335 
THR   H2   H N N 336 
THR   HA   H N N 337 
THR   HB   H N N 338 
THR   HG1  H N N 339 
THR   HG21 H N N 340 
THR   HG22 H N N 341 
THR   HG23 H N N 342 
THR   HXT  H N N 343 
TYR   N    N N N 344 
TYR   CA   C N S 345 
TYR   C    C N N 346 
TYR   O    O N N 347 
TYR   CB   C N N 348 
TYR   CG   C Y N 349 
TYR   CD1  C Y N 350 
TYR   CD2  C Y N 351 
TYR   CE1  C Y N 352 
TYR   CE2  C Y N 353 
TYR   CZ   C Y N 354 
TYR   OH   O N N 355 
TYR   OXT  O N N 356 
TYR   H    H N N 357 
TYR   H2   H N N 358 
TYR   HA   H N N 359 
TYR   HB2  H N N 360 
TYR   HB3  H N N 361 
TYR   HD1  H N N 362 
TYR   HD2  H N N 363 
TYR   HE1  H N N 364 
TYR   HE2  H N N 365 
TYR   HH   H N N 366 
TYR   HXT  H N N 367 
VAL   N    N N N 368 
VAL   CA   C N S 369 
VAL   C    C N N 370 
VAL   O    O N N 371 
VAL   CB   C N N 372 
VAL   CG1  C N N 373 
VAL   CG2  C N N 374 
VAL   OXT  O N N 375 
VAL   H    H N N 376 
VAL   H2   H N N 377 
VAL   HA   H N N 378 
VAL   HB   H N N 379 
VAL   HG11 H N N 380 
VAL   HG12 H N N 381 
VAL   HG13 H N N 382 
VAL   HG21 H N N 383 
VAL   HG22 H N N 384 
VAL   HG23 H N N 385 
VAL   HXT  H N N 386 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1A7V N   CA   sing N N 1   
A1A7V O   C    doub N N 2   
A1A7V C   CA   sing N N 3   
A1A7V CA  CB   sing N N 4   
A1A7V CB  SG   sing N N 5   
A1A7V SG  C1   sing N N 6   
A1A7V O1  C1   doub N N 7   
A1A7V O2  C2   sing N N 8   
A1A7V C1  C2   sing N N 9   
A1A7V C2  C3   sing N N 10  
A1A7V N   H    sing N N 11  
A1A7V N   H2   sing N N 12  
A1A7V CA  HA   sing N N 13  
A1A7V CB  HB3  sing N N 14  
A1A7V CB  HB2  sing N N 15  
A1A7V C2  H20  sing N N 16  
A1A7V O2  HO2  sing N N 17  
A1A7V C3  H3B  sing N N 18  
A1A7V C3  H3A  sing N N 19  
A1A7V C3  H3   sing N N 20  
A1A7V C   OXT  sing N N 21  
A1A7V OXT HXT  sing N N 22  
ALA   N   CA   sing N N 23  
ALA   N   H    sing N N 24  
ALA   N   H2   sing N N 25  
ALA   CA  C    sing N N 26  
ALA   CA  CB   sing N N 27  
ALA   CA  HA   sing N N 28  
ALA   C   O    doub N N 29  
ALA   C   OXT  sing N N 30  
ALA   CB  HB1  sing N N 31  
ALA   CB  HB2  sing N N 32  
ALA   CB  HB3  sing N N 33  
ALA   OXT HXT  sing N N 34  
ARG   N   CA   sing N N 35  
ARG   N   H    sing N N 36  
ARG   N   H2   sing N N 37  
ARG   CA  C    sing N N 38  
ARG   CA  CB   sing N N 39  
ARG   CA  HA   sing N N 40  
ARG   C   O    doub N N 41  
ARG   C   OXT  sing N N 42  
ARG   CB  CG   sing N N 43  
ARG   CB  HB2  sing N N 44  
ARG   CB  HB3  sing N N 45  
ARG   CG  CD   sing N N 46  
ARG   CG  HG2  sing N N 47  
ARG   CG  HG3  sing N N 48  
ARG   CD  NE   sing N N 49  
ARG   CD  HD2  sing N N 50  
ARG   CD  HD3  sing N N 51  
ARG   NE  CZ   sing N N 52  
ARG   NE  HE   sing N N 53  
ARG   CZ  NH1  sing N N 54  
ARG   CZ  NH2  doub N N 55  
ARG   NH1 HH11 sing N N 56  
ARG   NH1 HH12 sing N N 57  
ARG   NH2 HH21 sing N N 58  
ARG   NH2 HH22 sing N N 59  
ARG   OXT HXT  sing N N 60  
ASN   N   CA   sing N N 61  
ASN   N   H    sing N N 62  
ASN   N   H2   sing N N 63  
ASN   CA  C    sing N N 64  
ASN   CA  CB   sing N N 65  
ASN   CA  HA   sing N N 66  
ASN   C   O    doub N N 67  
ASN   C   OXT  sing N N 68  
ASN   CB  CG   sing N N 69  
ASN   CB  HB2  sing N N 70  
ASN   CB  HB3  sing N N 71  
ASN   CG  OD1  doub N N 72  
ASN   CG  ND2  sing N N 73  
ASN   ND2 HD21 sing N N 74  
ASN   ND2 HD22 sing N N 75  
ASN   OXT HXT  sing N N 76  
ASP   N   CA   sing N N 77  
ASP   N   H    sing N N 78  
ASP   N   H2   sing N N 79  
ASP   CA  C    sing N N 80  
ASP   CA  CB   sing N N 81  
ASP   CA  HA   sing N N 82  
ASP   C   O    doub N N 83  
ASP   C   OXT  sing N N 84  
ASP   CB  CG   sing N N 85  
ASP   CB  HB2  sing N N 86  
ASP   CB  HB3  sing N N 87  
ASP   CG  OD1  doub N N 88  
ASP   CG  OD2  sing N N 89  
ASP   OD2 HD2  sing N N 90  
ASP   OXT HXT  sing N N 91  
CYS   N   CA   sing N N 92  
CYS   N   H    sing N N 93  
CYS   N   H2   sing N N 94  
CYS   CA  C    sing N N 95  
CYS   CA  CB   sing N N 96  
CYS   CA  HA   sing N N 97  
CYS   C   O    doub N N 98  
CYS   C   OXT  sing N N 99  
CYS   CB  SG   sing N N 100 
CYS   CB  HB2  sing N N 101 
CYS   CB  HB3  sing N N 102 
CYS   SG  HG   sing N N 103 
CYS   OXT HXT  sing N N 104 
GLN   N   CA   sing N N 105 
GLN   N   H    sing N N 106 
GLN   N   H2   sing N N 107 
GLN   CA  C    sing N N 108 
GLN   CA  CB   sing N N 109 
GLN   CA  HA   sing N N 110 
GLN   C   O    doub N N 111 
GLN   C   OXT  sing N N 112 
GLN   CB  CG   sing N N 113 
GLN   CB  HB2  sing N N 114 
GLN   CB  HB3  sing N N 115 
GLN   CG  CD   sing N N 116 
GLN   CG  HG2  sing N N 117 
GLN   CG  HG3  sing N N 118 
GLN   CD  OE1  doub N N 119 
GLN   CD  NE2  sing N N 120 
GLN   NE2 HE21 sing N N 121 
GLN   NE2 HE22 sing N N 122 
GLN   OXT HXT  sing N N 123 
GLU   N   CA   sing N N 124 
GLU   N   H    sing N N 125 
GLU   N   H2   sing N N 126 
GLU   CA  C    sing N N 127 
GLU   CA  CB   sing N N 128 
GLU   CA  HA   sing N N 129 
GLU   C   O    doub N N 130 
GLU   C   OXT  sing N N 131 
GLU   CB  CG   sing N N 132 
GLU   CB  HB2  sing N N 133 
GLU   CB  HB3  sing N N 134 
GLU   CG  CD   sing N N 135 
GLU   CG  HG2  sing N N 136 
GLU   CG  HG3  sing N N 137 
GLU   CD  OE1  doub N N 138 
GLU   CD  OE2  sing N N 139 
GLU   OE2 HE2  sing N N 140 
GLU   OXT HXT  sing N N 141 
GLY   N   CA   sing N N 142 
GLY   N   H    sing N N 143 
GLY   N   H2   sing N N 144 
GLY   CA  C    sing N N 145 
GLY   CA  HA2  sing N N 146 
GLY   CA  HA3  sing N N 147 
GLY   C   O    doub N N 148 
GLY   C   OXT  sing N N 149 
GLY   OXT HXT  sing N N 150 
HIS   N   CA   sing N N 151 
HIS   N   H    sing N N 152 
HIS   N   H2   sing N N 153 
HIS   CA  C    sing N N 154 
HIS   CA  CB   sing N N 155 
HIS   CA  HA   sing N N 156 
HIS   C   O    doub N N 157 
HIS   C   OXT  sing N N 158 
HIS   CB  CG   sing N N 159 
HIS   CB  HB2  sing N N 160 
HIS   CB  HB3  sing N N 161 
HIS   CG  ND1  sing Y N 162 
HIS   CG  CD2  doub Y N 163 
HIS   ND1 CE1  doub Y N 164 
HIS   ND1 HD1  sing N N 165 
HIS   CD2 NE2  sing Y N 166 
HIS   CD2 HD2  sing N N 167 
HIS   CE1 NE2  sing Y N 168 
HIS   CE1 HE1  sing N N 169 
HIS   NE2 HE2  sing N N 170 
HIS   OXT HXT  sing N N 171 
HOH   O   H1   sing N N 172 
HOH   O   H2   sing N N 173 
ILE   N   CA   sing N N 174 
ILE   N   H    sing N N 175 
ILE   N   H2   sing N N 176 
ILE   CA  C    sing N N 177 
ILE   CA  CB   sing N N 178 
ILE   CA  HA   sing N N 179 
ILE   C   O    doub N N 180 
ILE   C   OXT  sing N N 181 
ILE   CB  CG1  sing N N 182 
ILE   CB  CG2  sing N N 183 
ILE   CB  HB   sing N N 184 
ILE   CG1 CD1  sing N N 185 
ILE   CG1 HG12 sing N N 186 
ILE   CG1 HG13 sing N N 187 
ILE   CG2 HG21 sing N N 188 
ILE   CG2 HG22 sing N N 189 
ILE   CG2 HG23 sing N N 190 
ILE   CD1 HD11 sing N N 191 
ILE   CD1 HD12 sing N N 192 
ILE   CD1 HD13 sing N N 193 
ILE   OXT HXT  sing N N 194 
LEU   N   CA   sing N N 195 
LEU   N   H    sing N N 196 
LEU   N   H2   sing N N 197 
LEU   CA  C    sing N N 198 
LEU   CA  CB   sing N N 199 
LEU   CA  HA   sing N N 200 
LEU   C   O    doub N N 201 
LEU   C   OXT  sing N N 202 
LEU   CB  CG   sing N N 203 
LEU   CB  HB2  sing N N 204 
LEU   CB  HB3  sing N N 205 
LEU   CG  CD1  sing N N 206 
LEU   CG  CD2  sing N N 207 
LEU   CG  HG   sing N N 208 
LEU   CD1 HD11 sing N N 209 
LEU   CD1 HD12 sing N N 210 
LEU   CD1 HD13 sing N N 211 
LEU   CD2 HD21 sing N N 212 
LEU   CD2 HD22 sing N N 213 
LEU   CD2 HD23 sing N N 214 
LEU   OXT HXT  sing N N 215 
LYS   N   CA   sing N N 216 
LYS   N   H    sing N N 217 
LYS   N   H2   sing N N 218 
LYS   CA  C    sing N N 219 
LYS   CA  CB   sing N N 220 
LYS   CA  HA   sing N N 221 
LYS   C   O    doub N N 222 
LYS   C   OXT  sing N N 223 
LYS   CB  CG   sing N N 224 
LYS   CB  HB2  sing N N 225 
LYS   CB  HB3  sing N N 226 
LYS   CG  CD   sing N N 227 
LYS   CG  HG2  sing N N 228 
LYS   CG  HG3  sing N N 229 
LYS   CD  CE   sing N N 230 
LYS   CD  HD2  sing N N 231 
LYS   CD  HD3  sing N N 232 
LYS   CE  NZ   sing N N 233 
LYS   CE  HE2  sing N N 234 
LYS   CE  HE3  sing N N 235 
LYS   NZ  HZ1  sing N N 236 
LYS   NZ  HZ2  sing N N 237 
LYS   NZ  HZ3  sing N N 238 
LYS   OXT HXT  sing N N 239 
MET   N   CA   sing N N 240 
MET   N   H    sing N N 241 
MET   N   H2   sing N N 242 
MET   CA  C    sing N N 243 
MET   CA  CB   sing N N 244 
MET   CA  HA   sing N N 245 
MET   C   O    doub N N 246 
MET   C   OXT  sing N N 247 
MET   CB  CG   sing N N 248 
MET   CB  HB2  sing N N 249 
MET   CB  HB3  sing N N 250 
MET   CG  SD   sing N N 251 
MET   CG  HG2  sing N N 252 
MET   CG  HG3  sing N N 253 
MET   SD  CE   sing N N 254 
MET   CE  HE1  sing N N 255 
MET   CE  HE2  sing N N 256 
MET   CE  HE3  sing N N 257 
MET   OXT HXT  sing N N 258 
PHE   N   CA   sing N N 259 
PHE   N   H    sing N N 260 
PHE   N   H2   sing N N 261 
PHE   CA  C    sing N N 262 
PHE   CA  CB   sing N N 263 
PHE   CA  HA   sing N N 264 
PHE   C   O    doub N N 265 
PHE   C   OXT  sing N N 266 
PHE   CB  CG   sing N N 267 
PHE   CB  HB2  sing N N 268 
PHE   CB  HB3  sing N N 269 
PHE   CG  CD1  doub Y N 270 
PHE   CG  CD2  sing Y N 271 
PHE   CD1 CE1  sing Y N 272 
PHE   CD1 HD1  sing N N 273 
PHE   CD2 CE2  doub Y N 274 
PHE   CD2 HD2  sing N N 275 
PHE   CE1 CZ   doub Y N 276 
PHE   CE1 HE1  sing N N 277 
PHE   CE2 CZ   sing Y N 278 
PHE   CE2 HE2  sing N N 279 
PHE   CZ  HZ   sing N N 280 
PHE   OXT HXT  sing N N 281 
PRO   N   CA   sing N N 282 
PRO   N   CD   sing N N 283 
PRO   N   H    sing N N 284 
PRO   CA  C    sing N N 285 
PRO   CA  CB   sing N N 286 
PRO   CA  HA   sing N N 287 
PRO   C   O    doub N N 288 
PRO   C   OXT  sing N N 289 
PRO   CB  CG   sing N N 290 
PRO   CB  HB2  sing N N 291 
PRO   CB  HB3  sing N N 292 
PRO   CG  CD   sing N N 293 
PRO   CG  HG2  sing N N 294 
PRO   CG  HG3  sing N N 295 
PRO   CD  HD2  sing N N 296 
PRO   CD  HD3  sing N N 297 
PRO   OXT HXT  sing N N 298 
SER   N   CA   sing N N 299 
SER   N   H    sing N N 300 
SER   N   H2   sing N N 301 
SER   CA  C    sing N N 302 
SER   CA  CB   sing N N 303 
SER   CA  HA   sing N N 304 
SER   C   O    doub N N 305 
SER   C   OXT  sing N N 306 
SER   CB  OG   sing N N 307 
SER   CB  HB2  sing N N 308 
SER   CB  HB3  sing N N 309 
SER   OG  HG   sing N N 310 
SER   OXT HXT  sing N N 311 
THR   N   CA   sing N N 312 
THR   N   H    sing N N 313 
THR   N   H2   sing N N 314 
THR   CA  C    sing N N 315 
THR   CA  CB   sing N N 316 
THR   CA  HA   sing N N 317 
THR   C   O    doub N N 318 
THR   C   OXT  sing N N 319 
THR   CB  OG1  sing N N 320 
THR   CB  CG2  sing N N 321 
THR   CB  HB   sing N N 322 
THR   OG1 HG1  sing N N 323 
THR   CG2 HG21 sing N N 324 
THR   CG2 HG22 sing N N 325 
THR   CG2 HG23 sing N N 326 
THR   OXT HXT  sing N N 327 
TYR   N   CA   sing N N 328 
TYR   N   H    sing N N 329 
TYR   N   H2   sing N N 330 
TYR   CA  C    sing N N 331 
TYR   CA  CB   sing N N 332 
TYR   CA  HA   sing N N 333 
TYR   C   O    doub N N 334 
TYR   C   OXT  sing N N 335 
TYR   CB  CG   sing N N 336 
TYR   CB  HB2  sing N N 337 
TYR   CB  HB3  sing N N 338 
TYR   CG  CD1  doub Y N 339 
TYR   CG  CD2  sing Y N 340 
TYR   CD1 CE1  sing Y N 341 
TYR   CD1 HD1  sing N N 342 
TYR   CD2 CE2  doub Y N 343 
TYR   CD2 HD2  sing N N 344 
TYR   CE1 CZ   doub Y N 345 
TYR   CE1 HE1  sing N N 346 
TYR   CE2 CZ   sing Y N 347 
TYR   CE2 HE2  sing N N 348 
TYR   CZ  OH   sing N N 349 
TYR   OH  HH   sing N N 350 
TYR   OXT HXT  sing N N 351 
VAL   N   CA   sing N N 352 
VAL   N   H    sing N N 353 
VAL   N   H2   sing N N 354 
VAL   CA  C    sing N N 355 
VAL   CA  CB   sing N N 356 
VAL   CA  HA   sing N N 357 
VAL   C   O    doub N N 358 
VAL   C   OXT  sing N N 359 
VAL   CB  CG1  sing N N 360 
VAL   CB  CG2  sing N N 361 
VAL   CB  HB   sing N N 362 
VAL   CG1 HG11 sing N N 363 
VAL   CG1 HG12 sing N N 364 
VAL   CG1 HG13 sing N N 365 
VAL   CG2 HG21 sing N N 366 
VAL   CG2 HG22 sing N N 367 
VAL   CG2 HG23 sing N N 368 
VAL   OXT HXT  sing N N 369 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           R35GM153337 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      Other 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          'Unpublished room temperature DJ-1 X-ray crystal structure' 
# 
_pdbx_serial_crystallography_data_reduction.diffrn_id             1 
_pdbx_serial_crystallography_data_reduction.frames_total          30000 
_pdbx_serial_crystallography_data_reduction.xfel_pulse_events     ? 
_pdbx_serial_crystallography_data_reduction.frame_hits            ? 
_pdbx_serial_crystallography_data_reduction.crystal_hits          1864 
_pdbx_serial_crystallography_data_reduction.droplet_hits          ? 
_pdbx_serial_crystallography_data_reduction.frames_failed_index   ? 
_pdbx_serial_crystallography_data_reduction.frames_indexed        1050 
_pdbx_serial_crystallography_data_reduction.lattices_indexed      ? 
_pdbx_serial_crystallography_data_reduction.xfel_run_numbers      ? 
_pdbx_serial_crystallography_data_reduction.lattices_merged       ? 
# 
_pdbx_serial_crystallography_sample_delivery.diffrn_id     1 
_pdbx_serial_crystallography_sample_delivery.description   'concentric flow injector' 
_pdbx_serial_crystallography_sample_delivery.method        injection 
# 
_pdbx_serial_crystallography_sample_delivery_injection.diffrn_id               1 
_pdbx_serial_crystallography_sample_delivery_injection.description             'flow-focused diffusive mixer' 
_pdbx_serial_crystallography_sample_delivery_injection.injector_diameter       ? 
_pdbx_serial_crystallography_sample_delivery_injection.injector_temperature    ? 
_pdbx_serial_crystallography_sample_delivery_injection.injector_pressure       ? 
_pdbx_serial_crystallography_sample_delivery_injection.flow_rate               1 
_pdbx_serial_crystallography_sample_delivery_injection.carrier_solvent         ? 
_pdbx_serial_crystallography_sample_delivery_injection.crystal_concentration   ? 
_pdbx_serial_crystallography_sample_delivery_injection.preparation             ? 
_pdbx_serial_crystallography_sample_delivery_injection.power_by                ? 
_pdbx_serial_crystallography_sample_delivery_injection.injector_nozzle         ? 
_pdbx_serial_crystallography_sample_delivery_injection.jet_diameter            ? 
_pdbx_serial_crystallography_sample_delivery_injection.filter_size             ? 
# 
_space_group.name_H-M_alt     'P 31 2 1' 
_space_group.name_Hall        
;P 31 2"
;
_space_group.IT_number        152 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9CFY 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.013153 
_atom_sites.fract_transf_matrix[1][2]   0.007594 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.015187 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.013134 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . ALA   A 1 5   ? 31.48144 8.76959   -1.02999 1.000 62.10856  ? 2   ALA   A N    1 
ATOM   2    C CA   . ALA   A 1 5   ? 32.92610 8.60944   -0.88206 1.000 85.32095  ? 2   ALA   A CA   1 
ATOM   3    C C    . ALA   A 1 5   ? 33.27985 8.21081   0.56122  1.000 75.96349  ? 2   ALA   A C    1 
ATOM   4    O O    . ALA   A 1 5   ? 34.45721 8.17330   0.94626  1.000 64.03824  ? 2   ALA   A O    1 
ATOM   5    C CB   . ALA   A 1 5   ? 33.65059 9.90085   -1.28284 1.000 64.85042  ? 2   ALA   A CB   1 
ATOM   6    H HA   . ALA   A 1 5   ? 33.23334 7.90455   -1.47337 1.000 102.47072 ? 2   ALA   A HA   1 
ATOM   7    H HB1  . ALA   A 1 5   ? 34.60611 9.77341   -1.17493 1.000 77.90609  ? 2   ALA   A HB1  1 
ATOM   8    H HB2  . ALA   A 1 5   ? 33.44639 10.10302  -2.20930 1.000 77.90609  ? 2   ALA   A HB2  1 
ATOM   9    H HB3  . ALA   A 1 5   ? 33.34671 10.62367  -0.71181 1.000 77.90609  ? 2   ALA   A HB3  1 
ATOM   10   N N    . SER   A 1 6   ? 32.25517 7.90871   1.35666  1.000 51.49765  ? 3   SER   A N    1 
ATOM   11   C CA   . SER   A 1 6   ? 32.44297 7.52909   2.75259  1.000 58.01018  ? 3   SER   A CA   1 
ATOM   12   C C    . SER   A 1 6   ? 32.56263 6.00978   2.87815  1.000 19.43897  ? 3   SER   A C    1 
ATOM   13   O O    . SER   A 1 6   ? 31.70889 5.27141   2.37074  1.000 36.73326  ? 3   SER   A O    1 
ATOM   14   C CB   . SER   A 1 6   ? 31.27571 8.05457   3.59261  1.000 54.06189  ? 3   SER   A CB   1 
ATOM   15   O OG   . SER   A 1 6   ? 31.55589 7.98902   4.97985  1.000 51.90058  ? 3   SER   A OG   1 
ATOM   16   H H    . SER   A 1 6   ? 31.43230 7.91682   1.10681  1.000 61.88276  ? 3   SER   A H    1 
ATOM   17   H HA   . SER   A 1 6   ? 33.26704 7.91301   3.09083  1.000 69.69780  ? 3   SER   A HA   1 
ATOM   18   H HB2  . SER   A 1 6   ? 31.10882 8.97912   3.35124  1.000 64.95985  ? 3   SER   A HB2  1 
ATOM   19   H HB3  . SER   A 1 6   ? 30.49041 7.51629   3.40702  1.000 64.95985  ? 3   SER   A HB3  1 
ATOM   20   H HG   . SER   A 1 6   ? 30.93907 8.35722   5.41524  1.000 62.36627  ? 3   SER   A HG   1 
ATOM   21   N N    . LYS   A 1 7   ? 33.63655 5.54723   3.53045  1.000 23.07953  ? 4   LYS   A N    1 
ATOM   22   C CA   . LYS   A 1 7   ? 33.78761 4.11987   3.80187  1.000 21.04513  ? 4   LYS   A CA   1 
ATOM   23   C C    . LYS   A 1 7   ? 32.78577 3.68244   4.87036  1.000 16.07510  ? 4   LYS   A C    1 
ATOM   24   O O    . LYS   A 1 7   ? 32.36826 4.47023   5.73008  1.000 13.44405  ? 4   LYS   A O    1 
ATOM   25   C CB   . LYS   A 1 7   ? 35.20287 3.78927   4.27160  1.000 22.11739  ? 4   LYS   A CB   1 
ATOM   26   C CG   . LYS   A 1 7   ? 36.33911 4.25093   3.35895  1.000 16.62887  ? 4   LYS   A CG   1 
ATOM   27   C CD   . LYS   A 1 7   ? 36.62913 3.31911   2.19707  1.000 28.58284  ? 4   LYS   A CD   1 
ATOM   28   C CE   . LYS   A 1 7   ? 37.79867 3.86345   1.35347  1.000 31.40215  ? 4   LYS   A CE   1 
ATOM   29   N NZ   . LYS   A 1 7   ? 38.26251 2.91718   0.29597  1.000 39.83241  ? 4   LYS   A NZ   1 
ATOM   30   H H    . LYS   A 1 7   ? 34.28173 6.03587   3.82125  1.000 27.78102  ? 4   LYS   A H    1 
ATOM   31   H HA   . LYS   A 1 7   ? 33.62522 3.62441   2.98391  1.000 25.33974  ? 4   LYS   A HA   1 
ATOM   32   H HB2  . LYS   A 1 7   ? 35.34099 4.20892   5.13514  1.000 26.62645  ? 4   LYS   A HB2  1 
ATOM   33   H HB3  . LYS   A 1 7   ? 35.27668 2.82572   4.35538  1.000 26.62645  ? 4   LYS   A HB3  1 
ATOM   34   H HG2  . LYS   A 1 7   ? 36.10678 5.11672   2.98836  1.000 20.04023  ? 4   LYS   A HG2  1 
ATOM   35   H HG3  . LYS   A 1 7   ? 37.15038 4.32247   3.88585  1.000 20.04023  ? 4   LYS   A HG3  1 
ATOM   36   H HD2  . LYS   A 1 7   ? 36.87232 2.44299   2.53496  1.000 34.38499  ? 4   LYS   A HD2  1 
ATOM   37   H HD3  . LYS   A 1 7   ? 35.84450 3.25028   1.63094  1.000 34.38499  ? 4   LYS   A HD3  1 
ATOM   38   H HE2  . LYS   A 1 7   ? 37.51508 4.68124   0.91565  1.000 37.76817  ? 4   LYS   A HE2  1 
ATOM   39   H HE3  . LYS   A 1 7   ? 38.55011 4.04430   1.93958  1.000 37.76817  ? 4   LYS   A HE3  1 
ATOM   40   H HZ1  . LYS   A 1 7   ? 38.92203 3.28584   -0.17437 1.000 47.88448  ? 4   LYS   A HZ1  1 
ATOM   41   H HZ2  . LYS   A 1 7   ? 38.55893 2.16542   0.66893  1.000 47.88448  ? 4   LYS   A HZ2  1 
ATOM   42   H HZ3  . LYS   A 1 7   ? 37.59028 2.72147   -0.25349 1.000 47.88448  ? 4   LYS   A HZ3  1 
ATOM   43   N N    . ARG   A 1 8   ? 32.40756 2.40917   4.81759  1.000 9.03420   ? 5   ARG   A N    1 
ATOM   44   C CA   . ARG   A 1 8   ? 31.33183 1.87216   5.63780  1.000 13.06744  ? 5   ARG   A CA   1 
ATOM   45   C C    . ARG   A 1 8   ? 31.85773 0.64682   6.36594  1.000 15.96348  ? 5   ARG   A C    1 
ATOM   46   O O    . ARG   A 1 8   ? 32.58365 -0.16393  5.78161  1.000 8.12857   ? 5   ARG   A O    1 
ATOM   47   C CB   . ARG   A 1 8   ? 30.09191 1.46437   4.81533  1.000 18.83637  ? 5   ARG   A CB   1 
ATOM   48   C CG   . ARG   A 1 8   ? 29.59390 2.48988   3.81055  1.000 30.92854  ? 5   ARG   A CG   1 
ATOM   49   C CD   . ARG   A 1 8   ? 28.48674 1.89216   2.92928  1.000 37.72520  ? 5   ARG   A CD   1 
ATOM   50   N NE   . ARG   A 1 8   ? 27.18708 2.07295   3.55695  1.000 47.16242  ? 5   ARG   A NE   1 
ATOM   51   C CZ   . ARG   A 1 8   ? 26.45404 3.16811   3.40906  1.000 83.19386  ? 5   ARG   A CZ   1 
ATOM   52   N NH1  . ARG   A 1 8   ? 26.84852 4.16505   2.62395  1.000 73.92094  ? 5   ARG   A NH1  1 
ATOM   53   N NH2  . ARG   A 1 8   ? 25.30095 3.27077   4.06481  1.000 73.94208  ? 5   ARG   A NH2  1 
ATOM   54   H H    . ARG   A 1 8   ? 32.76904 1.82415   4.30118  1.000 10.92662  ? 5   ARG   A H    1 
ATOM   55   H HA   . ARG   A 1 8   ? 31.05062 2.55149   6.27052  1.000 15.76652  ? 5   ARG   A HA   1 
ATOM   56   H HB2  . ARG   A 1 8   ? 30.30811 0.65898   4.31985  1.000 22.68922  ? 5   ARG   A HB2  1 
ATOM   57   H HB3  . ARG   A 1 8   ? 29.36344 1.28935   5.43145  1.000 22.68922  ? 5   ARG   A HB3  1 
ATOM   58   H HG2  . ARG   A 1 8   ? 29.23257 3.25690   4.28175  1.000 37.19983  ? 5   ARG   A HG2  1 
ATOM   59   H HG3  . ARG   A 1 8   ? 30.32711 2.76682   3.23905  1.000 37.19983  ? 5   ARG   A HG3  1 
ATOM   60   H HD2  . ARG   A 1 8   ? 28.47970 2.33858   2.06814  1.000 45.35583  ? 5   ARG   A HD2  1 
ATOM   61   H HD3  . ARG   A 1 8   ? 28.64345 0.94244   2.80935  1.000 45.35583  ? 5   ARG   A HD3  1 
ATOM   62   H HE   . ARG   A 1 8   ? 26.87874 1.43809   4.04836  1.000 56.68049  ? 5   ARG   A HE   1 
ATOM   63   H HH11 . ARG   A 1 8   ? 27.59369 4.10823   2.19840  1.000 88.79072  ? 5   ARG   A HH11 1 
ATOM   64   H HH12 . ARG   A 1 8   ? 26.35864 4.86705   2.54141  1.000 88.79072  ? 5   ARG   A HH12 1 
ATOM   65   H HH21 . ARG   A 1 8   ? 25.03918 2.63147   4.57702  1.000 88.81608  ? 5   ARG   A HH21 1 
ATOM   66   H HH22 . ARG   A 1 8   ? 24.81738 3.97643   3.97646  1.000 88.81608  ? 5   ARG   A HH22 1 
ATOM   67   N N    . ALA   A 1 9   ? 31.48881 0.50815   7.63719  1.000 7.01810   ? 6   ALA   A N    1 
ATOM   68   C CA   . ALA   A 1 9   ? 31.92893 -0.61658  8.44357  1.000 7.36721   ? 6   ALA   A CA   1 
ATOM   69   C C    . ALA   A 1 9   ? 30.72017 -1.27466  9.07351  1.000 5.61891   ? 6   ALA   A C    1 
ATOM   70   O O    . ALA   A 1 9   ? 29.81394 -0.58495  9.56162  1.000 5.78560   ? 6   ALA   A O    1 
ATOM   71   C CB   . ALA   A 1 9   ? 32.91560 -0.18032  9.54146  1.000 7.87080   ? 6   ALA   A CB   1 
ATOM   72   H H    . ALA   A 1 9   ? 30.97884 1.06048   8.05488  1.000 8.50731   ? 6   ALA   A H    1 
ATOM   73   H HA   . ALA   A 1 9   ? 32.37966 -1.26362  7.87870  1.000 8.92624   ? 6   ALA   A HA   1 
ATOM   74   H HB1  . ALA   A 1 9   ? 33.22838 -0.96664  10.01556 1.000 9.53054   ? 6   ALA   A HB1  1 
ATOM   75   H HB2  . ALA   A 1 9   ? 33.66495 0.27712   9.12900  1.000 9.53054   ? 6   ALA   A HB2  1 
ATOM   76   H HB3  . ALA   A 1 9   ? 32.46077 0.41708   10.15558 1.000 9.53054   ? 6   ALA   A HB3  1 
ATOM   77   N N    . LEU   A 1 10  ? 30.71587 -2.60986  9.06639  1.000 4.19894   ? 7   LEU   A N    1 
ATOM   78   C CA   . LEU   A 1 10  ? 29.68554 -3.38882  9.73583  1.000 5.20878   ? 7   LEU   A CA   1 
ATOM   79   C C    . LEU   A 1 10  ? 30.31323 -4.10339  10.92098 1.000 6.85089   ? 7   LEU   A C    1 
ATOM   80   O O    . LEU   A 1 10  ? 31.26125 -4.86467  10.73888 1.000 5.81471   ? 7   LEU   A O    1 
ATOM   81   C CB   . LEU   A 1 10  ? 29.07500 -4.42495  8.80615  1.000 3.92647   ? 7   LEU   A CB   1 
ATOM   82   C CG   . LEU   A 1 10  ? 27.98633 -5.31882  9.40393  1.000 15.15426  ? 7   LEU   A CG   1 
ATOM   83   C CD1  . LEU   A 1 10  ? 26.76202 -4.44882  9.69875  1.000 12.50466  ? 7   LEU   A CD1  1 
ATOM   84   C CD2  . LEU   A 1 10  ? 27.66073 -6.43499  8.44088  1.000 12.32407  ? 7   LEU   A CD2  1 
ATOM   85   H H    . LEU   A 1 10  ? 31.31137 -3.08931  8.67255  1.000 5.12431   ? 7   LEU   A H    1 
ATOM   86   H HA   . LEU   A 1 10  ? 28.98912 -2.78599  10.03996 1.000 6.33612   ? 7   LEU   A HA   1 
ATOM   87   H HB2  . LEU   A 1 10  ? 28.67941 -3.95785  8.05366  1.000 4.79734   ? 7   LEU   A HB2  1 
ATOM   88   H HB3  . LEU   A 1 10  ? 29.78592 -5.00844  8.49787  1.000 4.79734   ? 7   LEU   A HB3  1 
ATOM   89   H HG   . LEU   A 1 10  ? 28.27880 -5.73182  10.23145 1.000 18.27070  ? 7   LEU   A HG   1 
ATOM   90   H HD11 . LEU   A 1 10  ? 26.02196 -5.02135  9.95453  1.000 15.09118  ? 7   LEU   A HD11 1 
ATOM   91   H HD12 . LEU   A 1 10  ? 26.97455 -3.83957  10.42300 1.000 15.09118  ? 7   LEU   A HD12 1 
ATOM   92   H HD13 . LEU   A 1 10  ? 26.53173 -3.94704  8.90120  1.000 15.09118  ? 7   LEU   A HD13 1 
ATOM   93   H HD21 . LEU   A 1 10  ? 27.00362 -7.02130  8.84750  1.000 14.87447  ? 7   LEU   A HD21 1 
ATOM   94   H HD22 . LEU   A 1 10  ? 27.30289 -6.05309  7.62418  1.000 14.87447  ? 7   LEU   A HD22 1 
ATOM   95   H HD23 . LEU   A 1 10  ? 28.47137 -6.93100  8.24662  1.000 14.87447  ? 7   LEU   A HD23 1 
ATOM   96   N N    . VAL   A 1 11  ? 29.76892 -3.88852  12.11495 1.000 5.26645   ? 8   VAL   A N    1 
ATOM   97   C CA   . VAL   A 1 11  ? 30.18538 -4.57878  13.33091 1.000 3.74653   ? 8   VAL   A CA   1 
ATOM   98   C C    . VAL   A 1 11  ? 29.02476 -5.45323  13.74131 1.000 6.34817   ? 8   VAL   A C    1 
ATOM   99   O O    . VAL   A 1 11  ? 27.91791 -4.94577  13.92143 1.000 7.80474   ? 8   VAL   A O    1 
ATOM   100  C CB   . VAL   A 1 11  ? 30.54582 -3.58202  14.43847 1.000 3.14569   ? 8   VAL   A CB   1 
ATOM   101  C CG1  . VAL   A 1 11  ? 30.96128 -4.29199  15.67727 1.000 8.57682   ? 8   VAL   A CG1  1 
ATOM   102  C CG2  . VAL   A 1 11  ? 31.62693 -2.67820  13.91385 1.000 4.36193   ? 8   VAL   A CG2  1 
ATOM   103  H H    . VAL   A 1 11  ? 29.13259 -3.32604  12.25023 1.000 6.40532   ? 8   VAL   A H    1 
ATOM   104  H HA   . VAL   A 1 11  ? 30.96197 -5.13465  13.16118 1.000 4.58142   ? 8   VAL   A HA   1 
ATOM   105  H HB   . VAL   A 1 11  ? 29.77608 -3.04540  14.68430 1.000 3.86042   ? 8   VAL   A HB   1 
ATOM   106  H HG11 . VAL   A 1 11  ? 31.34182 -3.64986  16.29675 1.000 10.37776  ? 8   VAL   A HG11 1 
ATOM   107  H HG12 . VAL   A 1 11  ? 30.18395 -4.71457  16.07487 1.000 10.37776  ? 8   VAL   A HG12 1 
ATOM   108  H HG13 . VAL   A 1 11  ? 31.62277 -4.96388  15.44944 1.000 10.37776  ? 8   VAL   A HG13 1 
ATOM   109  H HG21 . VAL   A 1 11  ? 31.79013 -1.97314  14.55972 1.000 5.31990   ? 8   VAL   A HG21 1 
ATOM   110  H HG22 . VAL   A 1 11  ? 32.43518 -3.19747  13.77970 1.000 5.31990   ? 8   VAL   A HG22 1 
ATOM   111  H HG23 . VAL   A 1 11  ? 31.33666 -2.29452  13.07157 1.000 5.31990   ? 8   VAL   A HG23 1 
ATOM   112  N N    . ILE   A 1 12  ? 29.26038 -6.75754  13.86472 1.000 3.54182   ? 9   ILE   A N    1 
ATOM   113  C CA   . ILE   A 1 12  ? 28.21643 -7.73206  14.17804 1.000 2.57107   ? 9   ILE   A CA   1 
ATOM   114  C C    . ILE   A 1 12  ? 28.25264 -8.04483  15.66289 1.000 5.97537   ? 9   ILE   A C    1 
ATOM   115  O O    . ILE   A 1 12  ? 29.25184 -8.56009  16.17271 1.000 4.90441   ? 9   ILE   A O    1 
ATOM   116  C CB   . ILE   A 1 12  ? 28.38995 -9.02759  13.37430 1.000 9.16238   ? 9   ILE   A CB   1 
ATOM   117  C CG1  . ILE   A 1 12  ? 28.42487 -8.71952  11.88187 1.000 5.50950   ? 9   ILE   A CG1  1 
ATOM   118  C CG2  . ILE   A 1 12  ? 27.25841 -9.98883  13.70148 1.000 7.32375   ? 9   ILE   A CG2  1 
ATOM   119  C CD1  . ILE   A 1 12  ? 28.60814 -9.93723  11.03094 1.000 12.28988  ? 9   ILE   A CD1  1 
ATOM   120  H H    . ILE   A 1 12  ? 30.03809 -7.11194  13.76891 1.000 4.33577   ? 9   ILE   A H    1 
ATOM   121  H HA   . ILE   A 1 12  ? 27.36015 -7.32955  13.96433 1.000 3.17087   ? 9   ILE   A HA   1 
ATOM   122  H HB   . ILE   A 1 12  ? 29.23231 -9.44252  13.61752 1.000 11.08044  ? 9   ILE   A HB   1 
ATOM   123  H HG12 . ILE   A 1 12  ? 27.58707 -8.30174  11.62802 1.000 6.69699   ? 9   ILE   A HG12 1 
ATOM   124  H HG13 . ILE   A 1 12  ? 29.16365 -8.11691  11.70307 1.000 6.69699   ? 9   ILE   A HG13 1 
ATOM   125  H HG21 . ILE   A 1 12  ? 27.39271 -10.81389 13.20941 1.000 8.87408   ? 9   ILE   A HG21 1 
ATOM   126  H HG22 . ILE   A 1 12  ? 27.26189 -10.16794 14.65479 1.000 8.87408   ? 9   ILE   A HG22 1 
ATOM   127  H HG23 . ILE   A 1 12  ? 26.41549 -9.58366  13.44411 1.000 8.87408   ? 9   ILE   A HG23 1 
ATOM   128  H HD11 . ILE   A 1 12  ? 28.85702 -9.66175  10.13480 1.000 14.83344  ? 9   ILE   A HD11 1 
ATOM   129  H HD12 . ILE   A 1 12  ? 29.30869 -10.48785 11.41428 1.000 14.83344  ? 9   ILE   A HD12 1 
ATOM   130  H HD13 . ILE   A 1 12  ? 27.77471 -10.43284 11.00516 1.000 14.83344  ? 9   ILE   A HD13 1 
ATOM   131  N N    . LEU   A 1 13  ? 27.15587 -7.77385  16.34921 1.000 4.09932   ? 10  LEU   A N    1 
ATOM   132  C CA   . LEU   A 1 13  ? 27.12293 -7.79017  17.80597 1.000 6.47684   ? 10  LEU   A CA   1 
ATOM   133  C C    . LEU   A 1 13  ? 26.17648 -8.87701  18.25772 1.000 6.92272   ? 10  LEU   A C    1 
ATOM   134  O O    . LEU   A 1 13  ? 24.97145 -8.79584  17.98728 1.000 7.57528   ? 10  LEU   A O    1 
ATOM   135  C CB   . LEU   A 1 13  ? 26.65902 -6.44719  18.35226 1.000 9.73166   ? 10  LEU   A CB   1 
ATOM   136  C CG   . LEU   A 1 13  ? 26.52054 -6.33207  19.86381 1.000 12.90842  ? 10  LEU   A CG   1 
ATOM   137  C CD1  . LEU   A 1 13  ? 27.79375 -6.75834  20.55002 1.000 8.39411   ? 10  LEU   A CD1  1 
ATOM   138  C CD2  . LEU   A 1 13  ? 26.14508 -4.90395  20.24338 1.000 15.15136  ? 10  LEU   A CD2  1 
ATOM   139  H H    . LEU   A 1 13  ? 26.40149 -7.57329  15.98824 1.000 5.00477   ? 10  LEU   A H    1 
ATOM   140  H HA   . LEU   A 1 13  ? 28.01102 -7.98258  18.14534 1.000 7.85779   ? 10  LEU   A HA   1 
ATOM   141  H HB2  . LEU   A 1 13  ? 27.29908 -5.77362  18.07382 1.000 11.76358  ? 10  LEU   A HB2  1 
ATOM   142  H HB3  . LEU   A 1 13  ? 25.78778 -6.25425  17.97198 1.000 11.76358  ? 10  LEU   A HB3  1 
ATOM   143  H HG   . LEU   A 1 13  ? 25.81470 -6.92291  20.16973 1.000 15.57569  ? 10  LEU   A HG   1 
ATOM   144  H HD11 . LEU   A 1 13  ? 27.73188 -6.54152  21.49345 1.000 10.15852  ? 10  LEU   A HD11 1 
ATOM   145  H HD12 . LEU   A 1 13  ? 27.90825 -7.71494  20.43728 1.000 10.15852  ? 10  LEU   A HD12 1 
ATOM   146  H HD13 . LEU   A 1 13  ? 28.54110 -6.28639  20.15048 1.000 10.15852  ? 10  LEU   A HD13 1 
ATOM   147  H HD21 . LEU   A 1 13  ? 26.03317 -4.85194  21.20550 1.000 18.26722  ? 10  LEU   A HD21 1 
ATOM   148  H HD22 . LEU   A 1 13  ? 26.85363 -4.30518  19.95994 1.000 18.26722  ? 10  LEU   A HD22 1 
ATOM   149  H HD23 . LEU   A 1 13  ? 25.31513 -4.66731  19.80056 1.000 18.26722  ? 10  LEU   A HD23 1 
ATOM   150  N N    . ALA   A 1 14  ? 26.72381 -9.88916  18.92511 1.000 8.47870   ? 11  ALA   A N    1 
ATOM   151  C CA   . ALA   A 1 14  ? 25.96136 -11.01723 19.43465 1.000 9.68195   ? 11  ALA   A CA   1 
ATOM   152  C C    . ALA   A 1 14  ? 26.05163 -11.07244 20.95874 1.000 10.46575  ? 11  ALA   A C    1 
ATOM   153  O O    . ALA   A 1 14  ? 27.02185 -10.58792 21.57114 1.000 7.05983   ? 11  ALA   A O    1 
ATOM   154  C CB   . ALA   A 1 14  ? 26.46423 -12.33820 18.83341 1.000 13.76260  ? 11  ALA   A CB   1 
ATOM   155  H H    . ALA   A 1 14  ? 27.56417 -9.94377  19.09953 1.000 10.26003  ? 11  ALA   A H    1 
ATOM   156  H HA   . ALA   A 1 14  ? 25.02711 -10.90833 19.19755 1.000 11.70392  ? 11  ALA   A HA   1 
ATOM   157  H HB1  . ALA   A 1 14  ? 25.96814 -13.07321 19.22655 1.000 16.60070  ? 11  ALA   A HB1  1 
ATOM   158  H HB2  . ALA   A 1 14  ? 26.32540 -12.32138 17.87355 1.000 16.60070  ? 11  ALA   A HB2  1 
ATOM   159  H HB3  . ALA   A 1 14  ? 27.40932 -12.43479 19.02930 1.000 16.60070  ? 11  ALA   A HB3  1 
ATOM   160  N N    . LYS   A 1 15  ? 25.02100 -11.66336 21.56770 1.000 9.77952   ? 12  LYS   A N    1 
ATOM   161  C CA   . LYS   A 1 15  ? 25.05495 -11.92233 22.99826 1.000 10.30622  ? 12  LYS   A CA   1 
ATOM   162  C C    . LYS   A 1 15  ? 26.36119 -12.61212 23.35272 1.000 6.96260   ? 12  LYS   A C    1 
ATOM   163  O O    . LYS   A 1 15  ? 26.80819 -13.53494 22.65276 1.000 9.40566   ? 12  LYS   A O    1 
ATOM   164  C CB   . LYS   A 1 15  ? 23.86825 -12.78610 23.43193 1.000 8.66109   ? 12  LYS   A CB   1 
ATOM   165  C CG   . LYS   A 1 15  ? 23.91108 -13.16783 24.92954 1.000 16.64993  ? 12  LYS   A CG   1 
ATOM   166  C CD   . LYS   A 1 15  ? 22.53562 -13.56856 25.45735 1.000 31.88904  ? 12  LYS   A CD   1 
ATOM   167  C CE   . LYS   A 1 15  ? 22.24533 -12.92167 26.81534 1.000 43.87501  ? 12  LYS   A CE   1 
ATOM   168  N NZ   . LYS   A 1 15  ? 23.12499 -13.44717 27.90530 1.000 46.89936  ? 12  LYS   A NZ   1 
ATOM   169  H H    . LYS   A 1 15  ? 24.30014 -11.91951 21.17485 1.000 11.82101  ? 12  LYS   A H    1 
ATOM   170  H HA   . LYS   A 1 15  ? 24.98620 -11.08254 23.47880 1.000 12.45305  ? 12  LYS   A HA   1 
ATOM   171  H HB2  . LYS   A 1 15  ? 23.04707 -12.29521 23.27193 1.000 10.47889  ? 12  LYS   A HB2  1 
ATOM   172  H HB3  . LYS   A 1 15  ? 23.87068 -13.60636 22.91417 1.000 10.47889  ? 12  LYS   A HB3  1 
ATOM   173  H HG2  . LYS   A 1 15  ? 24.51243 -13.91925 25.05053 1.000 20.06550  ? 12  LYS   A HG2  1 
ATOM   174  H HG3  . LYS   A 1 15  ? 24.22296 -12.40710 25.44424 1.000 20.06550  ? 12  LYS   A HG3  1 
ATOM   175  H HD2  . LYS   A 1 15  ? 21.85419 -13.27993 24.83025 1.000 38.35243  ? 12  LYS   A HD2  1 
ATOM   176  H HD3  . LYS   A 1 15  ? 22.50086 -14.53195 25.56488 1.000 38.35243  ? 12  LYS   A HD3  1 
ATOM   177  H HE2  . LYS   A 1 15  ? 22.39061 -11.96500 26.74770 1.000 52.73560  ? 12  LYS   A HE2  1 
ATOM   178  H HE3  . LYS   A 1 15  ? 21.32416 -13.10081 27.06079 1.000 52.73560  ? 12  LYS   A HE3  1 
ATOM   179  H HZ1  . LYS   A 1 15  ? 23.95478 -13.14307 27.80002 1.000 56.36481  ? 12  LYS   A HZ1  1 
ATOM   180  H HZ2  . LYS   A 1 15  ? 22.81874 -13.18242 28.69790 1.000 56.36481  ? 12  LYS   A HZ2  1 
ATOM   181  H HZ3  . LYS   A 1 15  ? 23.13844 -14.33680 27.88332 1.000 56.36481  ? 12  LYS   A HZ3  1 
ATOM   182  N N    . GLY   A 1 16  ? 26.99216 -12.12076 24.41810 1.000 10.03843  ? 13  GLY   A N    1 
ATOM   183  C CA   . GLY   A 1 16  ? 28.24690 -12.66566 24.86534 1.000 6.15995   ? 13  GLY   A CA   1 
ATOM   184  C C    . GLY   A 1 16  ? 29.48026 -12.08334 24.22916 1.000 3.88834   ? 13  GLY   A C    1 
ATOM   185  O O    . GLY   A 1 16  ? 30.57667 -12.58481 24.50782 1.000 7.04797   ? 13  GLY   A O    1 
ATOM   186  H H    . GLY   A 1 16  ? 26.70221 -11.46646 24.89497 1.000 12.13170  ? 13  GLY   A H    1 
ATOM   187  H HA2  . GLY   A 1 16  ? 28.31846 -12.52476 25.82238 1.000 7.47753   ? 13  GLY   A HA2  1 
ATOM   188  H HA3  . GLY   A 1 16  ? 28.24858 -13.61883 24.68547 1.000 7.47753   ? 13  GLY   A HA3  1 
ATOM   189  N N    . ALA   A 1 17  ? 29.34227 -11.07725 23.36214 1.000 5.74346   ? 14  ALA   A N    1 
ATOM   190  C CA   . ALA   A 1 17  ? 30.50311 -10.40003 22.79908 1.000 4.51365   ? 14  ALA   A CA   1 
ATOM   191  C C    . ALA   A 1 17  ? 31.31065 -9.67265  23.87421 1.000 7.24699   ? 14  ALA   A C    1 
ATOM   192  O O    . ALA   A 1 17  ? 30.78788 -9.22558  24.89675 1.000 4.31808   ? 14  ALA   A O    1 
ATOM   193  C CB   . ALA   A 1 17  ? 30.06234 -9.39725  21.74067 1.000 3.46786   ? 14  ALA   A CB   1 
ATOM   194  H H    . ALA   A 1 17  ? 28.58745 -10.77091 23.08646 1.000 6.97773   ? 14  ALA   A H    1 
ATOM   195  H HA   . ALA   A 1 17  ? 31.08030 -11.06381 22.39024 1.000 5.50196   ? 14  ALA   A HA   1 
ATOM   196  H HB1  . ALA   A 1 17  ? 30.84699 -8.96358  21.37031 1.000 4.24701   ? 14  ALA   A HB1  1 
ATOM   197  H HB2  . ALA   A 1 17  ? 29.58276 -9.86722  21.04065 1.000 4.24701   ? 14  ALA   A HB2  1 
ATOM   198  H HB3  . ALA   A 1 17  ? 29.48313 -8.73724  22.15273 1.000 4.24701   ? 14  ALA   A HB3  1 
ATOM   199  N N    . GLU   A 1 18  ? 32.60362 -9.54021  23.63226 1.000 2.28209   ? 15  GLU   A N    1 
ATOM   200  C CA   . GLU   A 1 18  ? 33.44667 -8.77485  24.53599 1.000 1.81466   ? 15  GLU   A CA   1 
ATOM   201  C C    . GLU   A 1 18  ? 33.15717 -7.29972  24.27990 1.000 2.94247   ? 15  GLU   A C    1 
ATOM   202  O O    . GLU   A 1 18  ? 33.41421 -6.79965  23.17861 1.000 3.35537   ? 15  GLU   A O    1 
ATOM   203  C CB   . GLU   A 1 18  ? 34.92202 -9.12001  24.33135 1.000 4.65545   ? 15  GLU   A CB   1 
ATOM   204  C CG   . GLU   A 1 18  ? 35.66111 -9.31470  25.63988 1.000 5.11714   ? 15  GLU   A CG   1 
ATOM   205  C CD   . GLU   A 1 18  ? 35.63315 -8.03587  26.49566 1.000 5.35110   ? 15  GLU   A CD   1 
ATOM   206  O OE1  . GLU   A 1 18  ? 35.60652 -6.96098  25.88001 1.000 1.57769   ? 15  GLU   A OE1  1 
ATOM   207  O OE2  . GLU   A 1 18  ? 35.64213 -8.11063  27.75871 1.000 3.49194   ? 15  GLU   A OE2  1 
ATOM   208  H H    . GLU   A 1 18  ? 33.01423 -9.88056  22.95760 1.000 2.82409   ? 15  GLU   A H    1 
ATOM   209  H HA   . GLU   A 1 18  ? 33.24867 -8.98404  25.46224 1.000 2.26318   ? 15  GLU   A HA   1 
ATOM   210  H HB2  . GLU   A 1 18  ? 34.98664 -9.94394  23.82356 1.000 5.67212   ? 15  GLU   A HB2  1 
ATOM   211  H HB3  . GLU   A 1 18  ? 35.35174 -8.39748  23.84742 1.000 5.67212   ? 15  GLU   A HB3  1 
ATOM   212  H HG2  . GLU   A 1 18  ? 35.24022 -10.02890 26.14353 1.000 6.22615   ? 15  GLU   A HG2  1 
ATOM   213  H HG3  . GLU   A 1 18  ? 36.58664 -9.53929  25.45588 1.000 6.22615   ? 15  GLU   A HG3  1 
ATOM   214  N N    . GLU   A 1 19  ? 32.59320 -6.60766  25.28334 1.000 1.02346   ? 16  GLU   A N    1 
ATOM   215  C CA   . GLU   A 1 19  ? 32.13371 -5.23648  25.03695 1.000 1.29825   ? 16  GLU   A CA   1 
ATOM   216  C C    . GLU   A 1 19  ? 33.27961 -4.27169  24.74552 1.000 3.63339   ? 16  GLU   A C    1 
ATOM   217  O O    . GLU   A 1 19  ? 33.10437 -3.29022  24.01401 1.000 1.92742   ? 16  GLU   A O    1 
ATOM   218  C CB   . GLU   A 1 19  ? 31.31816 -4.72819  26.22238 1.000 1.26364   ? 16  GLU   A CB   1 
ATOM   219  C CG   . GLU   A 1 19  ? 31.86993 -5.04820  27.56766 1.000 3.94832   ? 16  GLU   A CG   1 
ATOM   220  C CD   . GLU   A 1 19  ? 31.28226 -6.35626  28.10473 1.000 5.77354   ? 16  GLU   A CD   1 
ATOM   221  O OE1  . GLU   A 1 19  ? 31.67209 -7.44158  27.63832 1.000 2.11772   ? 16  GLU   A OE1  1 
ATOM   222  O OE2  . GLU   A 1 19  ? 30.41406 -6.31994  29.00117 1.000 4.43129   ? 16  GLU   A OE2  1 
ATOM   223  H H    . GLU   A 1 19  ? 32.47082 -6.89917  26.08312 1.000 1.31374   ? 16  GLU   A H    1 
ATOM   224  H HA   . GLU   A 1 19  ? 31.56120 -5.25658  24.25418 1.000 1.64349   ? 16  GLU   A HA   1 
ATOM   225  H HB2  . GLU   A 1 19  ? 31.25708 -3.76224  26.15826 1.000 1.60196   ? 16  GLU   A HB2  1 
ATOM   226  H HB3  . GLU   A 1 19  ? 30.43243 -5.12060  26.17336 1.000 1.60196   ? 16  GLU   A HB3  1 
ATOM   227  H HG2  . GLU   A 1 19  ? 32.83304 -5.14613  27.50663 1.000 4.82356   ? 16  GLU   A HG2  1 
ATOM   228  H HG3  . GLU   A 1 19  ? 31.64753 -4.33462  28.18591 1.000 4.82356   ? 16  GLU   A HG3  1 
ATOM   229  N N    . MET   A 1 20  ? 34.43663 -4.49209  25.34724 1.000 3.19877   ? 17  MET   A N    1 
ATOM   230  C CA   . MET   A 1 20  ? 35.56432 -3.62950  25.04322 1.000 1.43585   ? 17  MET   A CA   1 
ATOM   231  C C    . MET   A 1 20  ? 35.97996 -3.78767  23.59021 1.000 3.24717   ? 17  MET   A C    1 
ATOM   232  O O    . MET   A 1 20  ? 36.30821 -2.80114  22.92002 1.000 1.52521   ? 17  MET   A O    1 
ATOM   233  C CB   . MET   A 1 20  ? 36.73573 -3.94378  25.96927 1.000 0.66903   ? 17  MET   A CB   1 
ATOM   234  C CG   . MET   A 1 20  ? 36.47017 -3.66052  27.44550 1.000 1.99028   ? 17  MET   A CG   1 
ATOM   235  S SD   . MET   A 1 20  ? 37.95679 -3.87623  28.42141 1.000 6.46338   ? 17  MET   A SD   1 
ATOM   236  C CE   . MET   A 1 20  ? 38.12434 -5.64653  28.56275 1.000 4.60211   ? 17  MET   A CE   1 
ATOM   237  H H    . MET   A 1 20  ? 34.59160 -5.11568  25.91883 1.000 3.92411   ? 17  MET   A H    1 
ATOM   238  H HA   . MET   A 1 20  ? 35.30504 -2.70880  25.20447 1.000 1.80861   ? 17  MET   A HA   1 
ATOM   239  H HB2  . MET   A 1 20  ? 36.95108 -4.88589  25.88598 1.000 0.88842   ? 17  MET   A HB2  1 
ATOM   240  H HB3  . MET   A 1 20  ? 37.49572 -3.40465  25.69973 1.000 0.88842   ? 17  MET   A HB3  1 
ATOM   241  H HG2  . MET   A 1 20  ? 36.16555 -2.74537  27.54844 1.000 2.47392   ? 17  MET   A HG2  1 
ATOM   242  H HG3  . MET   A 1 20  ? 35.79495 -4.27399  27.77509 1.000 2.47392   ? 17  MET   A HG3  1 
ATOM   243  H HE1  . MET   A 1 20  ? 37.80862 -5.92485  29.43668 1.000 5.60812   ? 17  MET   A HE1  1 
ATOM   244  H HE2  . MET   A 1 20  ? 37.59468 -6.07023  27.86933 1.000 5.60812   ? 17  MET   A HE2  1 
ATOM   245  H HE3  . MET   A 1 20  ? 39.05871 -5.88473  28.45730 1.000 5.60812   ? 17  MET   A HE3  1 
ATOM   246  N N    . GLU   A 1 21  ? 35.99672 -5.02785  23.09836 1.000 5.35695   ? 18  GLU   A N    1 
ATOM   247  C CA   . GLU   A 1 21  ? 36.38550 -5.31819  21.72802 1.000 5.22194   ? 18  GLU   A CA   1 
ATOM   248  C C    . GLU   A 1 21  ? 35.35010 -4.85536  20.72897 1.000 6.12670   ? 18  GLU   A C    1 
ATOM   249  O O    . GLU   A 1 21  ? 35.63429 -4.82025  19.53477 1.000 5.73353   ? 18  GLU   A O    1 
ATOM   250  C CB   . GLU   A 1 21  ? 36.59682 -6.81544  21.55209 1.000 3.80816   ? 18  GLU   A CB   1 
ATOM   251  C CG   . GLU   A 1 21  ? 37.74137 -7.34337  22.41269 1.000 3.00258   ? 18  GLU   A CG   1 
ATOM   252  C CD   . GLU   A 1 21  ? 37.80336 -8.88757  22.40169 1.000 7.02389   ? 18  GLU   A CD   1 
ATOM   253  O OE1  . GLU   A 1 21  ? 37.15283 -9.48740  21.51105 1.000 3.79308   ? 18  GLU   A OE1  1 
ATOM   254  O OE2  . GLU   A 1 21  ? 38.47711 -9.47352  23.28620 1.000 7.45452   ? 18  GLU   A OE2  1 
ATOM   255  H H    . GLU   A 1 21  ? 35.78269 -5.72794  23.54965 1.000 6.51393   ? 18  GLU   A H    1 
ATOM   256  H HA   . GLU   A 1 21  ? 37.22329 -4.86566  21.54300 1.000 6.35192   ? 18  GLU   A HA   1 
ATOM   257  H HB2  . GLU   A 1 21  ? 35.78604 -7.28267  21.80748 1.000 4.65537   ? 18  GLU   A HB2  1 
ATOM   258  H HB3  . GLU   A 1 21  ? 36.80715 -6.99941  20.62321 1.000 4.65537   ? 18  GLU   A HB3  1 
ATOM   259  H HG2  . GLU   A 1 21  ? 38.58249 -7.00300  22.06980 1.000 3.68868   ? 18  GLU   A HG2  1 
ATOM   260  H HG3  . GLU   A 1 21  ? 37.61383 -7.05086  23.32870 1.000 3.68868   ? 18  GLU   A HG3  1 
ATOM   261  N N    . THR   A 1 22  ? 34.15381 -4.54260  21.19137 1.000 2.46483   ? 19  THR   A N    1 
ATOM   262  C CA   . THR   A 1 22  ? 33.11321 -3.96352  20.36571 1.000 2.76786   ? 19  THR   A CA   1 
ATOM   263  C C    . THR   A 1 22  ? 33.22633 -2.44482  20.33893 1.000 4.83903   ? 19  THR   A C    1 
ATOM   264  O O    . THR   A 1 22  ? 33.29102 -1.85740  19.24986 1.000 3.19247   ? 19  THR   A O    1 
ATOM   265  C CB   . THR   A 1 22  ? 31.75550 -4.41435  20.89385 1.000 6.22863   ? 19  THR   A CB   1 
ATOM   266  O OG1  . THR   A 1 22  ? 31.71208 -5.84098  20.83432 1.000 6.98375   ? 19  THR   A OG1  1 
ATOM   267  C CG2  . THR   A 1 22  ? 30.63737 -3.86116  20.03523 1.000 8.32049   ? 19  THR   A CG2  1 
ATOM   268  H H    . THR   A 1 22  ? 33.91159 -4.66010  22.00815 1.000 3.04338   ? 19  THR   A H    1 
ATOM   269  H HA   . THR   A 1 22  ? 33.18864 -4.27672  19.45077 1.000 3.40702   ? 19  THR   A HA   1 
ATOM   270  H HB   . THR   A 1 22  ? 31.62706 -4.09831  21.80188 1.000 7.55994   ? 19  THR   A HB   1 
ATOM   271  H HG1  . THR   A 1 22  ? 32.37993 -6.16538  21.22718 1.000 8.46609   ? 19  THR   A HG1  1 
ATOM   272  H HG21 . THR   A 1 22  ? 29.79675 -4.28260  20.27324 1.000 10.07018  ? 19  THR   A HG21 1 
ATOM   273  H HG22 . THR   A 1 22  ? 30.55862 -2.90373  20.16949 1.000 10.07018  ? 19  THR   A HG22 1 
ATOM   274  H HG23 . THR   A 1 22  ? 30.82189 -4.03358  19.09869 1.000 10.07018  ? 19  THR   A HG23 1 
ATOM   275  N N    . VAL   A 1 23  ? 33.34196 -1.81355  21.52195 1.000 1.97673   ? 20  VAL   A N    1 
ATOM   276  C CA   . VAL   A 1 23  ? 33.22150 -0.34942  21.60995 1.000 2.53296   ? 20  VAL   A CA   1 
ATOM   277  C C    . VAL   A 1 23  ? 34.46723 0.34834   21.08804 1.000 1.66840   ? 20  VAL   A C    1 
ATOM   278  O O    . VAL   A 1 23  ? 34.39165 1.43768   20.49159 1.000 2.33254   ? 20  VAL   A O    1 
ATOM   279  C CB   . VAL   A 1 23  ? 32.91178 0.07252   23.06579 1.000 2.75215   ? 20  VAL   A CB   1 
ATOM   280  C CG1  . VAL   A 1 23  ? 32.98708 1.56577   23.23178 1.000 7.73278   ? 20  VAL   A CG1  1 
ATOM   281  C CG2  . VAL   A 1 23  ? 31.55164 -0.47036  23.45131 1.000 4.96195   ? 20  VAL   A CG2  1 
ATOM   282  H H    . VAL   A 1 23  ? 33.48761 -2.20381  22.27434 1.000 2.45766   ? 20  VAL   A H    1 
ATOM   283  H HA   . VAL   A 1 23  ? 32.48091 -0.07869  21.04504 1.000 3.12514   ? 20  VAL   A HA   1 
ATOM   284  H HB   . VAL   A 1 23  ? 33.57781 -0.29786  23.66589 1.000 3.38817   ? 20  VAL   A HB   1 
ATOM   285  H HG11 . VAL   A 1 23  ? 33.91766 1.82843   23.30880 1.000 9.36492   ? 20  VAL   A HG11 1 
ATOM   286  H HG12 . VAL   A 1 23  ? 32.58662 1.99024   22.45695 1.000 9.36492   ? 20  VAL   A HG12 1 
ATOM   287  H HG13 . VAL   A 1 23  ? 32.50438 1.81907   24.03411 1.000 9.36492   ? 20  VAL   A HG13 1 
ATOM   288  H HG21 . VAL   A 1 23  ? 31.28907 -0.08835  24.30338 1.000 6.03992   ? 20  VAL   A HG21 1 
ATOM   289  H HG22 . VAL   A 1 23  ? 30.90872 -0.22632  22.76722 1.000 6.03992   ? 20  VAL   A HG22 1 
ATOM   290  H HG23 . VAL   A 1 23  ? 31.60623 -1.43606  23.52453 1.000 6.03992   ? 20  VAL   A HG23 1 
ATOM   291  N N    . ILE   A 1 24  ? 35.63238 -0.24325  21.29874 1.000 0.24531   ? 21  ILE   A N    1 
ATOM   292  C CA   . ILE   A 1 24  ? 36.86089 0.45725   20.94829 1.000 0.56146   ? 21  ILE   A CA   1 
ATOM   293  C C    . ILE   A 1 24  ? 36.92481 0.61099   19.42833 1.000 0.13714   ? 21  ILE   A C    1 
ATOM   294  O O    . ILE   A 1 24  ? 37.19792 1.70404   18.92983 1.000 4.73261   ? 21  ILE   A O    1 
ATOM   295  C CB   . ILE   A 1 24  ? 38.08319 -0.26699  21.53091 1.000 1.75135   ? 21  ILE   A CB   1 
ATOM   296  C CG1  . ILE   A 1 24  ? 38.12382 -0.04196  23.05955 1.000 4.77307   ? 21  ILE   A CG1  1 
ATOM   297  C CG2  . ILE   A 1 24  ? 39.33649 0.25929   20.91057 1.000 3.92316   ? 21  ILE   A CG2  1 
ATOM   298  C CD1  . ILE   A 1 24  ? 39.14821 -0.86113  23.77574 1.000 4.58715   ? 21  ILE   A CD1  1 
ATOM   299  H H    . ILE   A 1 24  ? 35.73660 -1.02826  21.63413 1.000 0.37996   ? 21  ILE   A H    1 
ATOM   300  H HA   . ILE   A 1 24  ? 36.85154 1.35308   21.32019 1.000 0.75933   ? 21  ILE   A HA   1 
ATOM   301  H HB   . ILE   A 1 24  ? 38.01267 -1.21544  21.34016 1.000 2.18721   ? 21  ILE   A HB   1 
ATOM   302  H HG12 . ILE   A 1 24  ? 38.32330 0.89191   23.22982 1.000 5.81327   ? 21  ILE   A HG12 1 
ATOM   303  H HG13 . ILE   A 1 24  ? 37.25604 -0.26856  23.42903 1.000 5.81327   ? 21  ILE   A HG13 1 
ATOM   304  H HG21 . ILE   A 1 24  ? 40.09809 -0.05278  21.42386 1.000 4.79338   ? 21  ILE   A HG21 1 
ATOM   305  H HG22 . ILE   A 1 24  ? 39.39739 -0.06452  19.99824 1.000 4.79338   ? 21  ILE   A HG22 1 
ATOM   306  H HG23 . ILE   A 1 24  ? 39.30865 1.22888   20.91627 1.000 4.79338   ? 21  ILE   A HG23 1 
ATOM   307  H HD11 . ILE   A 1 24  ? 38.92896 -0.88560  24.72032 1.000 5.59017   ? 21  ILE   A HD11 1 
ATOM   308  H HD12 . ILE   A 1 24  ? 39.14431 -1.76028  23.41187 1.000 5.59017   ? 21  ILE   A HD12 1 
ATOM   309  H HD13 . ILE   A 1 24  ? 40.02079 -0.45682  23.64908 1.000 5.59017   ? 21  ILE   A HD13 1 
ATOM   310  N N    . PRO   A 1 25  ? 36.73801 -0.44107  18.64498 1.000 0.00008   ? 22  PRO   A N    1 
ATOM   311  C CA   . PRO   A 1 25  ? 36.79376 -0.24658  17.17497 1.000 1.23654   ? 22  PRO   A CA   1 
ATOM   312  C C    . PRO   A 1 25  ? 35.67844 0.65460   16.63658 1.000 1.08810   ? 22  PRO   A C    1 
ATOM   313  O O    . PRO   A 1 25  ? 35.86227 1.40234   15.65927 1.000 4.92824   ? 22  PRO   A O    1 
ATOM   314  C CB   . PRO   A 1 25  ? 36.70124 -1.68003  16.62827 1.000 5.11346   ? 22  PRO   A CB   1 
ATOM   315  C CG   . PRO   A 1 25  ? 37.06330 -2.58259  17.77174 1.000 6.49147   ? 22  PRO   A CG   1 
ATOM   316  C CD   . PRO   A 1 25  ? 36.58505 -1.84266  19.04300 1.000 1.06494   ? 22  PRO   A CD   1 
ATOM   317  H HA   . PRO   A 1 25  ? 37.65050 0.13402   16.92588 1.000 1.56943   ? 22  PRO   A HA   1 
ATOM   318  H HB2  . PRO   A 1 25  ? 35.79676 -1.85568  16.32503 1.000 6.22174   ? 22  PRO   A HB2  1 
ATOM   319  H HB3  . PRO   A 1 25  ? 37.32473 -1.78966  15.89333 1.000 6.22174   ? 22  PRO   A HB3  1 
ATOM   320  H HG2  . PRO   A 1 25  ? 36.60877 -3.43413  17.67595 1.000 7.87535   ? 22  PRO   A HG2  1 
ATOM   321  H HG3  . PRO   A 1 25  ? 38.02338 -2.71944  17.79215 1.000 7.87535   ? 22  PRO   A HG3  1 
ATOM   322  H HD2  . PRO   A 1 25  ? 35.65947 -2.05185  19.24412 1.000 1.36352   ? 22  PRO   A HD2  1 
ATOM   323  H HD3  . PRO   A 1 25  ? 37.14629 -2.05479  19.80518 1.000 1.36352   ? 22  PRO   A HD3  1 
ATOM   324  N N    . VAL   A 1 26  ? 34.48102 0.54393   17.19727 1.000 0.85678   ? 23  VAL   A N    1 
ATOM   325  C CA   . VAL   A 1 26  ? 33.39115 1.40216   16.73770 1.000 1.19183   ? 23  VAL   A CA   1 
ATOM   326  C C    . VAL   A 1 26  ? 33.74048 2.86853   16.96661 1.000 1.96337   ? 23  VAL   A C    1 
ATOM   327  O O    . VAL   A 1 26  ? 33.60341 3.72124   16.07458 1.000 5.94715   ? 23  VAL   A O    1 
ATOM   328  C CB   . VAL   A 1 26  ? 32.07827 1.01865   17.44002 1.000 1.01352   ? 23  VAL   A CB   1 
ATOM   329  C CG1  . VAL   A 1 26  ? 31.03985 2.11361   17.23782 1.000 3.71970   ? 23  VAL   A CG1  1 
ATOM   330  C CG2  . VAL   A 1 26  ? 31.59065 -0.31756  16.95403 1.000 2.27231   ? 23  VAL   A CG2  1 
ATOM   331  H H    . VAL   A 1 26  ? 34.27595 -0.00362  17.82793 1.000 1.11372   ? 23  VAL   A H    1 
ATOM   332  H HA   . VAL   A 1 26  ? 33.27227 1.26889   15.78428 1.000 1.51578   ? 23  VAL   A HA   1 
ATOM   333  H HB   . VAL   A 1 26  ? 32.23109 0.93390   18.39416 1.000 1.30181   ? 23  VAL   A HB   1 
ATOM   334  H HG11 . VAL   A 1 26  ? 30.15689 1.74464   17.39637 1.000 4.54922   ? 23  VAL   A HG11 1 
ATOM   335  H HG12 . VAL   A 1 26  ? 31.21456 2.83396   17.86349 1.000 4.54922   ? 23  VAL   A HG12 1 
ATOM   336  H HG13 . VAL   A 1 26  ? 31.10194 2.44357   16.32778 1.000 4.54922   ? 23  VAL   A HG13 1 
ATOM   337  H HG21 . VAL   A 1 26  ? 30.80118 -0.56829  17.45877 1.000 2.81236   ? 23  VAL   A HG21 1 
ATOM   338  H HG22 . VAL   A 1 26  ? 31.37293 -0.25042  16.01116 1.000 2.81236   ? 23  VAL   A HG22 1 
ATOM   339  H HG23 . VAL   A 1 26  ? 32.29050 -0.97614  17.08582 1.000 2.81236   ? 23  VAL   A HG23 1 
ATOM   340  N N    . ASP   A 1 27  ? 34.16133 3.18383   18.18694 1.000 1.79710   ? 24  ASP   A N    1 
ATOM   341  C CA   . ASP   A 1 27  ? 34.54645 4.54519   18.54366 1.000 1.78782   ? 24  ASP   A CA   1 
ATOM   342  C C    . ASP   A 1 27  ? 35.69375 5.03852   17.65654 1.000 3.27796   ? 24  ASP   A C    1 
ATOM   343  O O    . ASP   A 1 27  ? 35.61616 6.10101   17.03394 1.000 1.92252   ? 24  ASP   A O    1 
ATOM   344  C CB   . ASP   A 1 27  ? 34.90574 4.53980   20.04052 1.000 3.32234   ? 24  ASP   A CB   1 
ATOM   345  C CG   . ASP   A 1 27  ? 35.18099 5.89729   20.60552 1.000 5.75487   ? 24  ASP   A CG   1 
ATOM   346  O OD1  . ASP   A 1 27  ? 35.82287 6.73227   19.93253 1.000 5.19099   ? 24  ASP   A OD1  1 
ATOM   347  O OD2  . ASP   A 1 27  ? 34.84593 6.06913   21.79553 1.000 2.03975   ? 24  ASP   A OD2  1 
ATOM   348  H H    . ASP   A 1 27  ? 34.23435 2.62293   18.83475 1.000 2.24210   ? 24  ASP   A H    1 
ATOM   349  H HA   . ASP   A 1 27  ? 33.81840 5.17097   18.40496 1.000 2.23097   ? 24  ASP   A HA   1 
ATOM   350  H HB2  . ASP   A 1 27  ? 34.16470 4.15877   20.53710 1.000 4.07239   ? 24  ASP   A HB2  1 
ATOM   351  H HB3  . ASP   A 1 27  ? 35.70219 4.00087   20.16749 1.000 4.07239   ? 24  ASP   A HB3  1 
ATOM   352  N N    . VAL   A 1 28  ? 36.75385 4.25675   17.54198 1.000 1.89175   ? 25  VAL   A N    1 
ATOM   353  C CA   . VAL   A 1 28  ? 37.89827 4.72498   16.77735 1.000 1.51582   ? 25  VAL   A CA   1 
ATOM   354  C C    . VAL   A 1 28  ? 37.55476 4.86596   15.30883 1.000 5.83119   ? 25  VAL   A C    1 
ATOM   355  O O    . VAL   A 1 28  ? 38.03250 5.77794   14.63673 1.000 4.49039   ? 25  VAL   A O    1 
ATOM   356  C CB   . VAL   A 1 28  ? 39.06982 3.75353   16.97176 1.000 2.24915   ? 25  VAL   A CB   1 
ATOM   357  C CG1  . VAL   A 1 28  ? 40.16963 4.05597   15.96876 1.000 7.72351   ? 25  VAL   A CG1  1 
ATOM   358  C CG2  . VAL   A 1 28  ? 39.55981 3.86292   18.37410 1.000 3.38472   ? 25  VAL   A CG2  1 
ATOM   359  H H    . VAL   A 1 28  ? 36.83550 3.47305   17.88657 1.000 2.35569   ? 25  VAL   A H    1 
ATOM   360  H HA   . VAL   A 1 28  ? 38.14798 5.60252   17.10669 1.000 1.90457   ? 25  VAL   A HA   1 
ATOM   361  H HB   . VAL   A 1 28  ? 38.78430 2.83943   16.81752 1.000 2.78457   ? 25  VAL   A HB   1 
ATOM   362  H HG11 . VAL   A 1 28  ? 40.98843 3.62376   16.25802 1.000 9.35380   ? 25  VAL   A HG11 1 
ATOM   363  H HG12 . VAL   A 1 28  ? 39.90594 3.71675   15.09910 1.000 9.35380   ? 25  VAL   A HG12 1 
ATOM   364  H HG13 . VAL   A 1 28  ? 40.30052 5.01603   15.92353 1.000 9.35380   ? 25  VAL   A HG13 1 
ATOM   365  H HG21 . VAL   A 1 28  ? 40.31815 3.26946   18.49085 1.000 4.14724   ? 25  VAL   A HG21 1 
ATOM   366  H HG22 . VAL   A 1 28  ? 39.82776 4.77948   18.54441 1.000 4.14724   ? 25  VAL   A HG22 1 
ATOM   367  H HG23 . VAL   A 1 28  ? 38.84517 3.60938   18.97900 1.000 4.14724   ? 25  VAL   A HG23 1 
ATOM   368  N N    . MET   A 1 29  ? 36.75717 3.95229   14.77308 1.000 1.06560   ? 26  MET   A N    1 
ATOM   369  C CA   . MET   A 1 29  ? 36.42012 4.06212   13.37087 1.000 2.06336   ? 26  MET   A CA   1 
ATOM   370  C C    . MET   A 1 29  ? 35.57778 5.28737   13.12554 1.000 2.93177   ? 26  MET   A C    1 
ATOM   371  O O    . MET   A 1 29  ? 35.76661 5.96520   12.11007 1.000 3.53150   ? 26  MET   A O    1 
ATOM   372  C CB   . MET   A 1 29  ? 35.70120 2.82022   12.87206 1.000 2.33555   ? 26  MET   A CB   1 
ATOM   373  C CG   . MET   A 1 29  ? 36.66299 1.67509   12.58957 1.000 5.05141   ? 26  MET   A CG   1 
ATOM   374  S SD   . MET   A 1 29  ? 35.76897 0.31594   11.80956 1.000 6.07433   ? 26  MET   A SD   1 
ATOM   375  C CE   . MET   A 1 29  ? 34.74993 -0.35561  13.05564 1.000 2.37266   ? 26  MET   A CE   1 
ATOM   376  H H    . MET   A 1 29  ? 36.41145 3.28317   15.18824 1.000 1.36430   ? 26  MET   A H    1 
ATOM   377  H HA   . MET   A 1 29  ? 37.24782 4.12459   12.86896 1.000 2.56162   ? 26  MET   A HA   1 
ATOM   378  H HB2  . MET   A 1 29  ? 35.06952 2.52588   13.54678 1.000 2.88825   ? 26  MET   A HB2  1 
ATOM   379  H HB3  . MET   A 1 29  ? 35.23305 3.03260   12.04948 1.000 2.88825   ? 26  MET   A HB3  1 
ATOM   380  H HG2  . MET   A 1 29  ? 37.36353 1.97500   11.98941 1.000 6.14728   ? 26  MET   A HG2  1 
ATOM   381  H HG3  . MET   A 1 29  ? 37.05083 1.35929   13.42068 1.000 6.14728   ? 26  MET   A HG3  1 
ATOM   382  H HE1  . MET   A 1 29  ? 34.23146 -1.08468  12.68075 1.000 2.93278   ? 26  MET   A HE1  1 
ATOM   383  H HE2  . MET   A 1 29  ? 35.30849 -0.68393  13.77752 1.000 2.93278   ? 26  MET   A HE2  1 
ATOM   384  H HE3  . MET   A 1 29  ? 34.15631 0.33701   13.38549 1.000 2.93278   ? 26  MET   A HE3  1 
ATOM   385  N N    . ARG   A 1 30  ? 34.67948 5.61654   14.06217 1.000 2.23400   ? 27  ARG   A N    1 
ATOM   386  C CA   . ARG   A 1 30  ? 33.88510 6.82183   13.88826 1.000 3.50625   ? 27  ARG   A CA   1 
ATOM   387  C C    . ARG   A 1 30  ? 34.73462 8.07877   14.03084 1.000 7.19998   ? 27  ARG   A C    1 
ATOM   388  O O    . ARG   A 1 30  ? 34.47931 9.06728   13.34629 1.000 3.58717   ? 27  ARG   A O    1 
ATOM   389  C CB   . ARG   A 1 30  ? 32.71742 6.84161   14.86840 1.000 5.93507   ? 27  ARG   A CB   1 
ATOM   390  C CG   . ARG   A 1 30  ? 31.65186 5.82532   14.51421 1.000 2.79897   ? 27  ARG   A CG   1 
ATOM   391  C CD   . ARG   A 1 30  ? 30.47358 5.78352   15.44115 1.000 6.97738   ? 27  ARG   A CD   1 
ATOM   392  N NE   . ARG   A 1 30  ? 29.36949 5.01305   14.86682 1.000 11.07413  ? 27  ARG   A NE   1 
ATOM   393  C CZ   . ARG   A 1 30  ? 28.45311 4.35792   15.57640 1.000 7.43749   ? 27  ARG   A CZ   1 
ATOM   394  N NH1  . ARG   A 1 30  ? 28.47856 4.33948   16.89419 1.000 3.29430   ? 27  ARG   A NH1  1 
ATOM   395  N NH2  . ARG   A 1 30  ? 27.52159 3.64787   14.94785 1.000 5.43496   ? 27  ARG   A NH2  1 
ATOM   396  H H    . ARG   A 1 30  ? 34.52091 5.17050   14.78015 1.000 2.76638   ? 27  ARG   A H    1 
ATOM   397  H HA   . ARG   A 1 30  ? 33.50893 6.81772   12.99418 1.000 4.29308   ? 27  ARG   A HA   1 
ATOM   398  H HB2  . ARG   A 1 30  ? 33.04619 6.63732   15.75782 1.000 7.20767   ? 27  ARG   A HB2  1 
ATOM   399  H HB3  . ARG   A 1 30  ? 32.31034 7.72201   14.85927 1.000 7.20767   ? 27  ARG   A HB3  1 
ATOM   400  H HG2  . ARG   A 1 30  ? 31.31493 6.03025   13.62799 1.000 3.44435   ? 27  ARG   A HG2  1 
ATOM   401  H HG3  . ARG   A 1 30  ? 32.05522 4.94319   14.51999 1.000 3.44435   ? 27  ARG   A HG3  1 
ATOM   402  H HD2  . ARG   A 1 30  ? 30.73605 5.36539   16.27612 1.000 8.45844   ? 27  ARG   A HD2  1 
ATOM   403  H HD3  . ARG   A 1 30  ? 30.16213 6.68721   15.60619 1.000 8.45844   ? 27  ARG   A HD3  1 
ATOM   404  H HE   . ARG   A 1 30  ? 29.30836 4.98128   14.00959 1.000 13.37454  ? 27  ARG   A HE   1 
ATOM   405  H HH11 . ARG   A 1 30  ? 29.09872 4.75808   17.31820 1.000 4.03874   ? 27  ARG   A HH11 1 
ATOM   406  H HH12 . ARG   A 1 30  ? 27.87500 3.90886   17.32995 1.000 4.03874   ? 27  ARG   A HH12 1 
ATOM   407  H HH21 . ARG   A 1 30  ? 27.51366 3.61394   14.08856 1.000 6.60754   ? 27  ARG   A HH21 1 
ATOM   408  H HH22 . ARG   A 1 30  ? 26.92685 3.22243   15.40050 1.000 6.60754   ? 27  ARG   A HH22 1 
ATOM   409  N N    . ARG   A 1 31  ? 35.74806 8.06982   14.88792 1.000 3.44072   ? 28  ARG   A N    1 
ATOM   410  C CA   . ARG   A 1 31  ? 36.69164 9.17984   14.91784 1.000 4.68236   ? 28  ARG   A CA   1 
ATOM   411  C C    . ARG   A 1 31  ? 37.39224 9.37811   13.58831 1.000 3.81187   ? 28  ARG   A C    1 
ATOM   412  O O    . ARG   A 1 31  ? 37.81060 10.50024  13.27629 1.000 7.59052   ? 28  ARG   A O    1 
ATOM   413  C CB   . ARG   A 1 31  ? 37.75825 8.95236   15.99615 1.000 4.32264   ? 28  ARG   A CB   1 
ATOM   414  C CG   . ARG   A 1 31  ? 37.24683 9.06753   17.37358 1.000 5.80318   ? 28  ARG   A CG   1 
ATOM   415  C CD   . ARG   A 1 31  ? 38.28733 8.63543   18.38600 1.000 3.83520   ? 28  ARG   A CD   1 
ATOM   416  N NE   . ARG   A 1 31  ? 37.81505 8.82910   19.75500 1.000 8.93603   ? 28  ARG   A NE   1 
ATOM   417  C CZ   . ARG   A 1 31  ? 38.21134 9.82267   20.54618 1.000 3.12764   ? 28  ARG   A CZ   1 
ATOM   418  N NH1  . ARG   A 1 31  ? 39.10376 10.72215  20.13917 1.000 6.33779   ? 28  ARG   A NH1  1 
ATOM   419  N NH2  . ARG   A 1 31  ? 37.67026 9.94223   21.75511 1.000 6.39903   ? 28  ARG   A NH2  1 
ATOM   420  H H    . ARG   A 1 31  ? 35.91036 7.44344   15.45441 1.000 4.21445   ? 28  ARG   A H    1 
ATOM   421  H HA   . ARG   A 1 31  ? 36.18570 9.97972   15.13023 1.000 5.70442   ? 28  ARG   A HA   1 
ATOM   422  H HB2  . ARG   A 1 31  ? 38.12329 8.05998   15.88981 1.000 5.27276   ? 28  ARG   A HB2  1 
ATOM   423  H HB3  . ARG   A 1 31  ? 38.45960 9.61313   15.88481 1.000 5.27276   ? 28  ARG   A HB3  1 
ATOM   424  H HG2  . ARG   A 1 31  ? 37.01092 9.99111   17.55318 1.000 7.04940   ? 28  ARG   A HG2  1 
ATOM   425  H HG3  . ARG   A 1 31  ? 36.46688 8.49998   17.47587 1.000 7.04940   ? 28  ARG   A HG3  1 
ATOM   426  H HD2  . ARG   A 1 31  ? 38.48473 7.69390   18.26170 1.000 4.68782   ? 28  ARG   A HD2  1 
ATOM   427  H HD3  . ARG   A 1 31  ? 39.09258 9.16220   18.26367 1.000 4.68782   ? 28  ARG   A HD3  1 
ATOM   428  H HE   . ARG   A 1 31  ? 37.24571 8.26608   20.06879 1.000 10.80882  ? 28  ARG   A HE   1 
ATOM   429  H HH11 . ARG   A 1 31  ? 39.43803 10.66898  19.34858 1.000 7.69093   ? 28  ARG   A HH11 1 
ATOM   430  H HH12 . ARG   A 1 31  ? 39.34617 11.35658  20.66675 1.000 7.69093   ? 28  ARG   A HH12 1 
ATOM   431  H HH21 . ARG   A 1 31  ? 37.07264 9.38157   22.01611 1.000 7.76442   ? 28  ARG   A HH21 1 
ATOM   432  H HH22 . ARG   A 1 31  ? 37.91798 10.58020  22.27590 1.000 7.76442   ? 28  ARG   A HH22 1 
ATOM   433  N N    . ALA   A 1 32  ? 37.58666 8.30515   12.82849 1.000 5.62720   ? 29  ALA   A N    1 
ATOM   434  C CA   . ALA   A 1 32  ? 38.22979 8.36329   11.52290 1.000 5.14305   ? 29  ALA   A CA   1 
ATOM   435  C C    . ALA   A 1 32  ? 37.26212 8.70166   10.42285 1.000 7.75022   ? 29  ALA   A C    1 
ATOM   436  O O    . ALA   A 1 32  ? 37.64066 8.67630   9.25492  1.000 13.11766  ? 29  ALA   A O    1 
ATOM   437  C CB   . ALA   A 1 32  ? 38.88842 7.02373   11.19859 1.000 5.43014   ? 29  ALA   A CB   1 
ATOM   438  H H    . ALA   A 1 32  ? 37.34783 7.51049   13.05448 1.000 6.83823   ? 29  ALA   A H    1 
ATOM   439  H HA   . ALA   A 1 32  ? 38.92000 9.04409   11.55463 1.000 6.25725   ? 29  ALA   A HA   1 
ATOM   440  H HB1  . ALA   A 1 32  ? 39.30841 7.08134   10.32614 1.000 6.60175   ? 29  ALA   A HB1  1 
ATOM   441  H HB2  . ALA   A 1 32  ? 39.55585 6.82808   11.87473 1.000 6.60175   ? 29  ALA   A HB2  1 
ATOM   442  H HB3  . ALA   A 1 32  ? 38.20949 6.33096   11.19378 1.000 6.60175   ? 29  ALA   A HB3  1 
ATOM   443  N N    . GLY   A 1 33  ? 36.02140 9.02584   10.76110 1.000 6.92492   ? 30  GLY   A N    1 
ATOM   444  C CA   . GLY   A 1 33  ? 35.07948 9.42758   9.74674  1.000 11.52781  ? 30  GLY   A CA   1 
ATOM   445  C C    . GLY   A 1 33  ? 34.40902 8.28759   9.02231  1.000 7.07120   ? 30  GLY   A C    1 
ATOM   446  O O    . GLY   A 1 33  ? 33.65282 8.53677   8.08437  1.000 6.94152   ? 30  GLY   A O    1 
ATOM   447  H H    . GLY   A 1 33  ? 35.71110 9.01907   11.56314 1.000 8.39549   ? 30  GLY   A H    1 
ATOM   448  H HA2  . GLY   A 1 33  ? 34.38593 9.96433   10.16120 1.000 13.91895  ? 30  GLY   A HA2  1 
ATOM   449  H HA3  . GLY   A 1 33  ? 35.54364 9.96614   9.08688  1.000 13.91895  ? 30  GLY   A HA3  1 
ATOM   450  N N    . ILE   A 1 34  ? 34.62106 7.06064   9.45805  1.000 7.13866   ? 31  ILE   A N    1 
ATOM   451  C CA   . ILE   A 1 34  ? 33.96379 5.89606   8.87835  1.000 10.11099  ? 31  ILE   A CA   1 
ATOM   452  C C    . ILE   A 1 34  ? 32.52177 5.80470   9.37075  1.000 13.38938  ? 31  ILE   A C    1 
ATOM   453  O O    . ILE   A 1 34  ? 32.21623 6.09574   10.53268 1.000 10.48107  ? 31  ILE   A O    1 
ATOM   454  C CB   . ILE   A 1 34  ? 34.77812 4.63715   9.23253  1.000 8.19665   ? 31  ILE   A CB   1 
ATOM   455  C CG1  . ILE   A 1 34  ? 36.17686 4.72471   8.62405  1.000 11.60265  ? 31  ILE   A CG1  1 
ATOM   456  C CG2  . ILE   A 1 34  ? 34.06492 3.37875   8.76780  1.000 14.78262  ? 31  ILE   A CG2  1 
ATOM   457  C CD1  . ILE   A 1 34  ? 37.21808 3.78502   9.26136  1.000 20.55977  ? 31  ILE   A CD1  1 
ATOM   458  H H    . ILE   A 1 34  ? 35.15379 6.86618   10.10457 1.000 8.65198   ? 31  ILE   A H    1 
ATOM   459  H HA   . ILE   A 1 34  ? 33.92255 5.98706   7.91351  1.000 12.21877  ? 31  ILE   A HA   1 
ATOM   460  H HB   . ILE   A 1 34  ? 34.86269 4.59250   10.19781 1.000 9.92156   ? 31  ILE   A HB   1 
ATOM   461  H HG12 . ILE   A 1 34  ? 36.11778 4.49893   7.68254  1.000 14.00876  ? 31  ILE   A HG12 1 
ATOM   462  H HG13 . ILE   A 1 34  ? 36.50146 5.63289   8.72769  1.000 14.00876  ? 31  ILE   A HG13 1 
ATOM   463  H HG21 . ILE   A 1 34  ? 34.66306 2.62166   8.86751  1.000 17.82472  ? 31  ILE   A HG21 1 
ATOM   464  H HG22 . ILE   A 1 34  ? 33.27139 3.24702   9.30989  1.000 17.82472  ? 31  ILE   A HG22 1 
ATOM   465  H HG23 . ILE   A 1 34  ? 33.81556 3.48285   7.83619  1.000 17.82472  ? 31  ILE   A HG23 1 
ATOM   466  H HD11 . ILE   A 1 34  ? 38.09396 3.99267   8.89994  1.000 24.75731  ? 31  ILE   A HD11 1 
ATOM   467  H HD12 . ILE   A 1 34  ? 37.21683 3.91759   10.22226 1.000 24.75731  ? 31  ILE   A HD12 1 
ATOM   468  H HD13 . ILE   A 1 34  ? 36.98378 2.86691   9.05381  1.000 24.75731  ? 31  ILE   A HD13 1 
ATOM   469  N N    . LYS   A 1 35  ? 31.61195 5.43645   8.47003  1.000 3.59389   ? 32  LYS   A N    1 
ATOM   470  C CA   A LYS   A 1 35  ? 30.21691 5.21539   8.83084  0.425 6.92468   ? 32  LYS   A CA   1 
ATOM   471  C CA   B LYS   A 1 35  ? 30.21823 5.21570   8.83180  0.575 6.80789   ? 32  LYS   A CA   1 
ATOM   472  C C    . LYS   A 1 35  ? 30.09399 3.78714   9.33945  1.000 10.98728  ? 32  LYS   A C    1 
ATOM   473  O O    . LYS   A 1 35  ? 30.24701 2.83087   8.56975  1.000 11.28439  ? 32  LYS   A O    1 
ATOM   474  C CB   A LYS   A 1 35  ? 29.29162 5.45947   7.64016  0.425 15.36725  ? 32  LYS   A CB   1 
ATOM   475  C CB   B LYS   A 1 35  ? 29.30492 5.46075   7.63353  0.575 15.37124  ? 32  LYS   A CB   1 
ATOM   476  C CG   A LYS   A 1 35  ? 29.04239 6.92630   7.33785  0.425 17.51323  ? 32  LYS   A CG   1 
ATOM   477  C CG   B LYS   A 1 35  ? 27.83298 5.56415   7.97786  0.575 16.92080  ? 32  LYS   A CG   1 
ATOM   478  C CD   A LYS   A 1 35  ? 27.60857 7.15653   6.85364  0.425 29.39082  ? 32  LYS   A CD   1 
ATOM   479  C CD   B LYS   A 1 35  ? 26.97668 5.78023   6.70652  0.575 27.04028  ? 32  LYS   A CD   1 
ATOM   480  C CE   A LYS   A 1 35  ? 27.55408 7.54965   5.37780  0.425 40.34152  ? 32  LYS   A CE   1 
ATOM   481  C CE   B LYS   A 1 35  ? 27.55275 6.87510   5.79292  0.575 41.40143  ? 32  LYS   A CE   1 
ATOM   482  N NZ   A LYS   A 1 35  ? 26.13986 7.69643   4.90110  0.425 41.88911  ? 32  LYS   A NZ   1 
ATOM   483  N NZ   B LYS   A 1 35  ? 26.67853 7.16837   4.60653  0.575 50.07384  ? 32  LYS   A NZ   1 
ATOM   484  H H    A LYS   A 1 35  ? 31.78128 5.30756   7.63678  0.425 4.39826   ? 32  LYS   A H    1 
ATOM   485  H H    B LYS   A 1 35  ? 31.78098 5.30757   7.63671  0.575 4.39826   ? 32  LYS   A H    1 
ATOM   486  H HA   A LYS   A 1 35  ? 29.95634 5.83506   9.53014  0.425 8.39521   ? 32  LYS   A HA   1 
ATOM   487  H HA   B LYS   A 1 35  ? 29.95304 5.83074   9.53344  0.575 8.25505   ? 32  LYS   A HA   1 
ATOM   488  H HB2  A LYS   A 1 35  ? 29.68938 5.05959   6.85099  0.425 18.52629  ? 32  LYS   A HB2  1 
ATOM   489  H HB2  B LYS   A 1 35  ? 29.56637 6.29373   7.21082  0.575 18.53107  ? 32  LYS   A HB2  1 
ATOM   490  H HB3  A LYS   A 1 35  ? 28.43334 5.04681   7.82445  0.425 18.52629  ? 32  LYS   A HB3  1 
ATOM   491  H HB3  B LYS   A 1 35  ? 29.40918 4.72519   7.00985  0.575 18.53107  ? 32  LYS   A HB3  1 
ATOM   492  H HG2  A LYS   A 1 35  ? 29.18126 7.44943   8.14280  0.425 21.10146  ? 32  LYS   A HG2  1 
ATOM   493  H HG2  B LYS   A 1 35  ? 27.54339 4.74365   8.40661  0.575 20.39054  ? 32  LYS   A HG2  1 
ATOM   494  H HG3  A LYS   A 1 35  ? 29.65119 7.22000   6.64215  0.425 21.10146  ? 32  LYS   A HG3  1 
ATOM   495  H HG3  B LYS   A 1 35  ? 27.69290 6.31695   8.57331  0.575 20.39054  ? 32  LYS   A HG3  1 
ATOM   496  H HD2  A LYS   A 1 35  ? 27.09865 6.33927   6.96747  0.425 35.35457  ? 32  LYS   A HD2  1 
ATOM   497  H HD2  B LYS   A 1 35  ? 26.94314 4.95294   6.20117  0.575 32.53392  ? 32  LYS   A HD2  1 
ATOM   498  H HD3  A LYS   A 1 35  ? 27.20827 7.87222   7.37176  0.425 35.35457  ? 32  LYS   A HD3  1 
ATOM   499  H HD3  B LYS   A 1 35  ? 26.08109 6.04605   6.96759  0.575 32.53392  ? 32  LYS   A HD3  1 
ATOM   500  H HE2  A LYS   A 1 35  ? 28.00740 8.39828   5.25440  0.425 48.49541  ? 32  LYS   A HE2  1 
ATOM   501  H HE2  B LYS   A 1 35  ? 27.64820 7.69424   6.30360  0.575 49.76731  ? 32  LYS   A HE2  1 
ATOM   502  H HE3  A LYS   A 1 35  ? 27.98563 6.86262   4.84615  0.425 48.49541  ? 32  LYS   A HE3  1 
ATOM   503  H HE3  B LYS   A 1 35  ? 28.41819 6.58734   5.46259  0.575 49.76731  ? 32  LYS   A HE3  1 
ATOM   504  H HZ1  A LYS   A 1 35  ? 26.13095 7.96799   4.05359  0.425 50.35251  ? 32  LYS   A HZ1  1 
ATOM   505  H HZ1  B LYS   A 1 35  ? 27.06016 7.78674   4.09265  0.575 60.17419  ? 32  LYS   A HZ1  1 
ATOM   506  H HZ2  A LYS   A 1 35  ? 25.71664 6.91562   4.95868  0.425 50.35251  ? 32  LYS   A HZ2  1 
ATOM   507  H HZ2  B LYS   A 1 35  ? 26.55803 6.42843   4.12688  0.575 60.17419  ? 32  LYS   A HZ2  1 
ATOM   508  H HZ3  A LYS   A 1 35  ? 25.71080 8.29507   5.40074  0.425 50.35251  ? 32  LYS   A HZ3  1 
ATOM   509  H HZ3  B LYS   A 1 35  ? 25.88610 7.46818   4.87904  0.575 60.17419  ? 32  LYS   A HZ3  1 
ATOM   510  N N    . VAL   A 1 36  ? 29.82061 3.64156   10.63053 1.000 10.45654  ? 33  VAL   A N    1 
ATOM   511  C CA   . VAL   A 1 36  ? 29.77822 2.34478   11.29212 1.000 5.03097   ? 33  VAL   A CA   1 
ATOM   512  C C    . VAL   A 1 36  ? 28.34031 1.98918   11.62103 1.000 9.20582   ? 33  VAL   A C    1 
ATOM   513  O O    . VAL   A 1 36  ? 27.62179 2.79160   12.22943 1.000 9.17639   ? 33  VAL   A O    1 
ATOM   514  C CB   . VAL   A 1 36  ? 30.63375 2.34483   12.57275 1.000 10.80877  ? 33  VAL   A CB   1 
ATOM   515  C CG1  . VAL   A 1 36  ? 30.55088 0.99421   13.23581 1.000 5.09904   ? 33  VAL   A CG1  1 
ATOM   516  C CG2  . VAL   A 1 36  ? 32.05121 2.76879   12.23112 1.000 7.87938   ? 33  VAL   A CG2  1 
ATOM   517  H H    . VAL   A 1 36  ? 29.65151 4.29909   11.15842 1.000 12.63343  ? 33  VAL   A H    1 
ATOM   518  H HA   . VAL   A 1 36  ? 30.11819 1.67609   10.67716 1.000 6.12275   ? 33  VAL   A HA   1 
ATOM   519  H HB   . VAL   A 1 36  ? 30.30176 2.98667   13.21983 1.000 13.05611  ? 33  VAL   A HB   1 
ATOM   520  H HG11 . VAL   A 1 36  ? 31.24827 0.92849   13.90680 1.000 6.20443   ? 33  VAL   A HG11 1 
ATOM   521  H HG12 . VAL   A 1 36  ? 29.68034 0.90021   13.65322 1.000 6.20443   ? 33  VAL   A HG12 1 
ATOM   522  H HG13 . VAL   A 1 36  ? 30.67191 0.30478   12.56430 1.000 6.20443   ? 33  VAL   A HG13 1 
ATOM   523  H HG21 . VAL   A 1 36  ? 32.60670 2.67934   13.02126 1.000 9.54084   ? 33  VAL   A HG21 1 
ATOM   524  H HG22 . VAL   A 1 36  ? 32.38929 2.19876   11.52283 1.000 9.54084   ? 33  VAL   A HG22 1 
ATOM   525  H HG23 . VAL   A 1 36  ? 32.04203 3.69279   11.93610 1.000 9.54084   ? 33  VAL   A HG23 1 
ATOM   526  N N    . THR   A 1 37  ? 27.95190 0.75876   11.28907 1.000 4.13541   ? 34  THR   A N    1 
ATOM   527  C CA   . THR   A 1 37  ? 26.66693 0.19834   11.68219 1.000 9.21897   ? 34  THR   A CA   1 
ATOM   528  C C    . THR   A 1 37  ? 26.93116 -0.91797  12.66724 1.000 7.65104   ? 34  THR   A C    1 
ATOM   529  O O    . THR   A 1 37  ? 27.54350 -1.92865  12.31220 1.000 8.52290   ? 34  THR   A O    1 
ATOM   530  C CB   . THR   A 1 37  ? 25.87789 -0.35125  10.49459 1.000 8.86906   ? 34  THR   A CB   1 
ATOM   531  O OG1  . THR   A 1 37  ? 25.65747 0.70565   9.56430  1.000 9.03347   ? 34  THR   A OG1  1 
ATOM   532  C CG2  . THR   A 1 37  ? 24.54421 -0.95000  10.94103 1.000 9.50671   ? 34  THR   A CG2  1 
ATOM   533  H H    . THR   A 1 37  ? 28.43131 0.21741   10.82356 1.000 5.04808   ? 34  THR   A H    1 
ATOM   534  H HA   . THR   A 1 37  ? 26.13581 0.89837   12.09301 1.000 11.14835  ? 34  THR   A HA   1 
ATOM   535  H HB   . THR   A 1 37  ? 26.37842 -1.06447  10.06834 1.000 10.72845  ? 34  THR   A HB   1 
ATOM   536  H HG1  . THR   A 1 37  ? 26.38536 0.93722   9.21479  1.000 10.92575  ? 34  THR   A HG1  1 
ATOM   537  H HG21 . THR   A 1 37  ? 24.00740 -1.17896  10.16623 1.000 11.49364  ? 34  THR   A HG21 1 
ATOM   538  H HG22 . THR   A 1 37  ? 24.69917 -1.75168  11.46467 1.000 11.49364  ? 34  THR   A HG22 1 
ATOM   539  H HG23 . THR   A 1 37  ? 24.05768 -0.30923  11.48288 1.000 11.49364  ? 34  THR   A HG23 1 
ATOM   540  N N    . VAL   A 1 38  ? 26.45455 -0.74134  13.88976 1.000 4.47365   ? 35  VAL   A N    1 
ATOM   541  C CA   . VAL   A 1 38  ? 26.49054 -1.80206  14.88050 1.000 2.86424   ? 35  VAL   A CA   1 
ATOM   542  C C    . VAL   A 1 38  ? 25.20786 -2.60115  14.70923 1.000 5.13875   ? 35  VAL   A C    1 
ATOM   543  O O    . VAL   A 1 38  ? 24.11625 -2.12176  15.02039 1.000 11.42635  ? 35  VAL   A O    1 
ATOM   544  C CB   . VAL   A 1 38  ? 26.64281 -1.25247  16.30008 1.000 7.80230   ? 35  VAL   A CB   1 
ATOM   545  C CG1  . VAL   A 1 38  ? 26.65530 -2.39347  17.26500 1.000 10.84915  ? 35  VAL   A CG1  1 
ATOM   546  C CG2  . VAL   A 1 38  ? 27.94381 -0.45737  16.40245 1.000 6.59707   ? 35  VAL   A CG2  1 
ATOM   547  H H    . VAL   A 1 38  ? 26.10228 -0.00898  14.17107 1.000 5.45397   ? 35  VAL   A H    1 
ATOM   548  H HA   . VAL   A 1 38  ? 27.24774 -2.38594  14.71734 1.000 3.52268   ? 35  VAL   A HA   1 
ATOM   549  H HB   . VAL   A 1 38  ? 25.90308 -0.66329  16.51587 1.000 9.44835   ? 35  VAL   A HB   1 
ATOM   550  H HG11 . VAL   A 1 38  ? 26.94435 -2.07015  18.13265 1.000 13.10457  ? 35  VAL   A HG11 1 
ATOM   551  H HG12 . VAL   A 1 38  ? 25.76021 -2.76146  17.33052 1.000 13.10457  ? 35  VAL   A HG12 1 
ATOM   552  H HG13 . VAL   A 1 38  ? 27.26926 -3.07217  16.94358 1.000 13.10457  ? 35  VAL   A HG13 1 
ATOM   553  H HG21 . VAL   A 1 38  ? 28.03308 -0.11264  17.30472 1.000 8.00207   ? 35  VAL   A HG21 1 
ATOM   554  H HG22 . VAL   A 1 38  ? 28.68903 -1.04332  16.19698 1.000 8.00207   ? 35  VAL   A HG22 1 
ATOM   555  H HG23 . VAL   A 1 38  ? 27.91591 0.27679   15.76910 1.000 8.00207   ? 35  VAL   A HG23 1 
ATOM   556  N N    . ALA   A 1 39  ? 25.33729 -3.82470  14.20798 1.000 9.79686   ? 36  ALA   A N    1 
ATOM   557  C CA   . ALA   A 1 39  ? 24.19629 -4.64188  13.83313 1.000 5.55877   ? 36  ALA   A CA   1 
ATOM   558  C C    . ALA   A 1 39  ? 24.02613 -5.78772  14.81236 1.000 9.97632   ? 36  ALA   A C    1 
ATOM   559  O O    . ALA   A 1 39  ? 24.96833 -6.54096  15.07574 1.000 9.26406   ? 36  ALA   A O    1 
ATOM   560  C CB   . ALA   A 1 39  ? 24.35774 -5.18987  12.41575 1.000 11.37859  ? 36  ALA   A CB   1 
ATOM   561  H H    . ALA   A 1 39  ? 26.09479 -4.20916  14.07389 1.000 11.84182  ? 36  ALA   A H    1 
ATOM   562  H HA   . ALA   A 1 39  ? 23.39564 -4.09543  13.86863 1.000 6.75611   ? 36  ALA   A HA   1 
ATOM   563  H HB1  . ALA   A 1 39  ? 23.58000 -5.72533  12.19370 1.000 13.73989  ? 36  ALA   A HB1  1 
ATOM   564  H HB2  . ALA   A 1 39  ? 24.43550 -4.44698  11.79691 1.000 13.73989  ? 36  ALA   A HB2  1 
ATOM   565  H HB3  . ALA   A 1 39  ? 25.15779 -5.73702  12.37794 1.000 13.73989  ? 36  ALA   A HB3  1 
ATOM   566  N N    . GLY   A 1 40  ? 22.81737 -5.92675  15.34372 1.000 7.78292   ? 37  GLY   A N    1 
ATOM   567  C CA   . GLY   A 1 40  ? 22.56080 -6.97638  16.30681 1.000 10.03592  ? 37  GLY   A CA   1 
ATOM   568  C C    . GLY   A 1 40  ? 22.22074 -8.25958  15.58985 1.000 12.12531  ? 37  GLY   A C    1 
ATOM   569  O O    . GLY   A 1 40  ? 21.33522 -8.28084  14.72981 1.000 9.55419   ? 37  GLY   A O    1 
ATOM   570  H H    . GLY   A 1 40  ? 22.13929 -5.42978  15.16255 1.000 9.42509   ? 37  GLY   A H    1 
ATOM   571  H HA2  . GLY   A 1 40  ? 23.34684 -7.12056  16.85658 1.000 12.12868  ? 37  GLY   A HA2  1 
ATOM   572  H HA3  . GLY   A 1 40  ? 21.81739 -6.72714  16.87788 1.000 12.12868  ? 37  GLY   A HA3  1 
ATOM   573  N N    . LEU   A 1 41  ? 22.91485 -9.34385  15.95836 1.000 12.98547  ? 38  LEU   A N    1 
ATOM   574  C CA   . LEU   A 1 41  ? 22.69785 -10.63298 15.30655 1.000 22.09236  ? 38  LEU   A CA   1 
ATOM   575  C C    . LEU   A 1 41  ? 21.24222 -11.06349 15.39941 1.000 23.25246  ? 38  LEU   A C    1 
ATOM   576  O O    . LEU   A 1 41  ? 20.66627 -11.51551 14.41088 1.000 20.68944  ? 38  LEU   A O    1 
ATOM   577  C CB   . LEU   A 1 41  ? 23.59504 -11.69919 15.93146 1.000 13.52718  ? 38  LEU   A CB   1 
ATOM   578  C CG   . LEU   A 1 41  ? 23.63245 -13.11591 15.36650 1.000 26.56972  ? 38  LEU   A CG   1 
ATOM   579  C CD1  . LEU   A 1 41  ? 24.09941 -13.09479 13.93152 1.000 29.54147  ? 38  LEU   A CD1  1 
ATOM   580  C CD2  . LEU   A 1 41  ? 24.54771 -14.01512 16.19952 1.000 25.70675  ? 38  LEU   A CD2  1 
ATOM   581  H H    . LEU   A 1 41  ? 23.51125 -9.35666  16.57782 1.000 15.66815  ? 38  LEU   A H    1 
ATOM   582  H HA   . LEU   A 1 41  ? 22.93306 -10.54403 14.36971 1.000 26.59642  ? 38  LEU   A HA   1 
ATOM   583  H HB2  . LEU   A 1 41  ? 24.50552 -11.36837 15.88174 1.000 16.31820  ? 38  LEU   A HB2  1 
ATOM   584  H HB3  . LEU   A 1 41  ? 23.32493 -11.78916 16.85874 1.000 16.31820  ? 38  LEU   A HB3  1 
ATOM   585  H HG   . LEU   A 1 41  ? 22.73626 -13.48561 15.39919 1.000 31.96925  ? 38  LEU   A HG   1 
ATOM   586  H HD11 . LEU   A 1 41  ? 23.32503 -13.07618 13.34767 1.000 35.53535  ? 38  LEU   A HD11 1 
ATOM   587  H HD12 . LEU   A 1 41  ? 24.64143 -12.30336 13.78741 1.000 35.53535  ? 38  LEU   A HD12 1 
ATOM   588  H HD13 . LEU   A 1 41  ? 24.62492 -13.89157 13.75867 1.000 35.53535  ? 38  LEU   A HD13 1 
ATOM   589  H HD21 . LEU   A 1 41  ? 24.49463 -14.92184 15.85902 1.000 30.93368  ? 38  LEU   A HD21 1 
ATOM   590  H HD22 . LEU   A 1 41  ? 25.45859 -13.68880 16.13091 1.000 30.93368  ? 38  LEU   A HD22 1 
ATOM   591  H HD23 . LEU   A 1 41  ? 24.25672 -13.99161 17.12455 1.000 30.93368  ? 38  LEU   A HD23 1 
ATOM   592  N N    . ALA   A 1 42  ? 20.61750 -10.89743 16.56140 1.000 21.44841  ? 39  ALA   A N    1 
ATOM   593  C CA   . ALA   A 1 42  ? 19.28135 -11.43340 16.81885 1.000 29.60402  ? 39  ALA   A CA   1 
ATOM   594  C C    . ALA   A 1 42  ? 18.13490 -10.44114 16.58820 1.000 23.48031  ? 39  ALA   A C    1 
ATOM   595  O O    . ALA   A 1 42  ? 16.96465 -10.80144 16.78768 1.000 30.62236  ? 39  ALA   A O    1 
ATOM   596  C CB   . ALA   A 1 42  ? 19.22534 -11.95292 18.25983 1.000 26.30508  ? 39  ALA   A CB   1 
ATOM   597  H H    . ALA   A 1 42  ? 20.95181 -10.47056 17.22895 1.000 25.82367  ? 39  ALA   A H    1 
ATOM   598  H HA   . ALA   A 1 42  ? 19.12867 -12.16687 16.20273 1.000 35.61041  ? 39  ALA   A HA   1 
ATOM   599  H HB1  . ALA   A 1 42  ? 18.33391 -12.29059 18.43937 1.000 31.65168  ? 39  ALA   A HB1  1 
ATOM   600  H HB2  . ALA   A 1 42  ? 19.87596 -12.66471 18.36442 1.000 31.65168  ? 39  ALA   A HB2  1 
ATOM   601  H HB3  . ALA   A 1 42  ? 19.43153 -11.22456 18.86636 1.000 31.65168  ? 39  ALA   A HB3  1 
ATOM   602  N N    . GLY   A 1 43  ? 18.43106 -9.22069  16.17681 1.000 22.28453  ? 40  GLY   A N    1 
ATOM   603  C CA   . GLY   A 1 43  ? 17.43287 -8.19322  16.00279 1.000 18.54912  ? 40  GLY   A CA   1 
ATOM   604  C C    . GLY   A 1 43  ? 17.92929 -6.87772  16.55278 1.000 28.02300  ? 40  GLY   A C    1 
ATOM   605  O O    . GLY   A 1 43  ? 19.10629 -6.71493  16.85694 1.000 16.85392  ? 40  GLY   A O    1 
ATOM   606  H H    . GLY   A 1 43  ? 19.22846 -8.96006  15.98754 1.000 26.82702  ? 40  GLY   A H    1 
ATOM   607  H HA2  . GLY   A 1 43  ? 17.23413 -8.08363  15.05972 1.000 22.34453  ? 40  GLY   A HA2  1 
ATOM   608  H HA3  . GLY   A 1 43  ? 16.61991 -8.44150  16.47008 1.000 22.34453  ? 40  GLY   A HA3  1 
ATOM   609  N N    . LYS   A 1 44  ? 17.01156 -5.92424  16.66993 1.000 16.65041  ? 41  LYS   A N    1 
ATOM   610  C CA   . LYS   A 1 44  ? 17.29806 -4.56045  17.09903 1.000 23.90886  ? 41  LYS   A CA   1 
ATOM   611  C C    . LYS   A 1 44  ? 17.36444 -4.42703  18.61627 1.000 17.85387  ? 41  LYS   A C    1 
ATOM   612  O O    . LYS   A 1 44  ? 17.74472 -3.36644  19.11807 1.000 27.18909  ? 41  LYS   A O    1 
ATOM   613  C CB   . LYS   A 1 44  ? 16.21710 -3.62492  16.50749 1.000 24.51165  ? 41  LYS   A CB   1 
ATOM   614  C CG   . LYS   A 1 44  ? 16.28788 -2.17744  16.95710 1.000 63.09816  ? 41  LYS   A CG   1 
ATOM   615  C CD   . LYS   A 1 44  ? 16.99924 -1.29815  15.92611 1.000 56.88407  ? 41  LYS   A CD   1 
ATOM   616  C CE   . LYS   A 1 44  ? 16.58437 0.16855   16.07455 1.000 65.46594  ? 41  LYS   A CE   1 
ATOM   617  N NZ   . LYS   A 1 44  ? 15.10771 0.35139   15.87934 1.000 69.51722  ? 41  LYS   A NZ   1 
ATOM   618  H H    . LYS   A 1 44  ? 16.17768 -6.04704  16.49914 1.000 20.06608  ? 41  LYS   A H    1 
ATOM   619  H HA   . LYS   A 1 44  ? 18.15989 -4.27239  16.75968 1.000 28.77622  ? 41  LYS   A HA   1 
ATOM   620  H HB2  . LYS   A 1 44  ? 16.30367 -3.63154  15.54138 1.000 29.49957  ? 41  LYS   A HB2  1 
ATOM   621  H HB3  . LYS   A 1 44  ? 15.34578 -3.96473  16.76484 1.000 29.49957  ? 41  LYS   A HB3  1 
ATOM   622  H HG2  . LYS   A 1 44  ? 15.38841 -1.83548  17.07924 1.000 75.80338  ? 41  LYS   A HG2  1 
ATOM   623  H HG3  . LYS   A 1 44  ? 16.77900 -2.12485  17.79192 1.000 75.80338  ? 41  LYS   A HG3  1 
ATOM   624  H HD2  . LYS   A 1 44  ? 17.95856 -1.36022  16.05554 1.000 68.34647  ? 41  LYS   A HD2  1 
ATOM   625  H HD3  . LYS   A 1 44  ? 16.76518 -1.59424  15.03255 1.000 68.34647  ? 41  LYS   A HD3  1 
ATOM   626  H HE2  . LYS   A 1 44  ? 16.81385 0.47764   16.96489 1.000 78.64471  ? 41  LYS   A HE2  1 
ATOM   627  H HE3  . LYS   A 1 44  ? 17.04721 0.70112   15.40893 1.000 78.64471  ? 41  LYS   A HE3  1 
ATOM   628  H HZ1  . LYS   A 1 44  ? 14.84886 -0.04522  15.12582 1.000 83.50625  ? 41  LYS   A HZ1  1 
ATOM   629  H HZ2  . LYS   A 1 44  ? 14.66366 -0.00764  16.56200 1.000 83.50625  ? 41  LYS   A HZ2  1 
ATOM   630  H HZ3  . LYS   A 1 44  ? 14.91203 1.21829   15.83143 1.000 83.50625  ? 41  LYS   A HZ3  1 
ATOM   631  N N    . ASP   A 1 45  ? 17.03439 -5.47050  19.35967 1.000 16.87395  ? 42  ASP   A N    1 
ATOM   632  C CA   . ASP   A 1 45  ? 16.90687 -5.32918  20.80108 1.000 15.39858  ? 42  ASP   A CA   1 
ATOM   633  C C    . ASP   A 1 45  ? 18.27570 -5.20985  21.47561 1.000 16.23661  ? 42  ASP   A C    1 
ATOM   634  O O    . ASP   A 1 45  ? 19.30704 -5.58224  20.91199 1.000 9.76886   ? 42  ASP   A O    1 
ATOM   635  C CB   . ASP   A 1 45  ? 16.13043 -6.51319  21.36789 1.000 25.47177  ? 42  ASP   A CB   1 
ATOM   636  C CG   . ASP   A 1 45  ? 14.72528 -6.60865  20.78843 1.000 45.07086  ? 42  ASP   A CG   1 
ATOM   637  O OD1  . ASP   A 1 45  ? 14.11178 -5.53933  20.52895 1.000 38.90176  ? 42  ASP   A OD1  1 
ATOM   638  O OD2  . ASP   A 1 45  ? 14.25653 -7.74653  20.57737 1.000 44.92862  ? 42  ASP   A OD2  1 
ATOM   639  H H    . ASP   A 1 45  ? 16.88076 -6.26140  19.05886 1.000 20.33432  ? 42  ASP   A H    1 
ATOM   640  H HA   . ASP   A 1 45  ? 16.42040 -4.51481  21.00370 1.000 18.56388  ? 42  ASP   A HA   1 
ATOM   641  H HB2  . ASP   A 1 45  ? 16.60164 -7.33403  21.15555 1.000 30.65171  ? 42  ASP   A HB2  1 
ATOM   642  H HB3  . ASP   A 1 45  ? 16.05486 -6.41334  22.32977 1.000 30.65171  ? 42  ASP   A HB3  1 
ATOM   643  N N    . PRO   A 1 46  ? 18.30756 -4.68310  22.68903 1.000 18.55414  ? 43  PRO   A N    1 
ATOM   644  C CA   . PRO   A 1 46  ? 19.59959 -4.48634  23.37160 1.000 11.03898  ? 43  PRO   A CA   1 
ATOM   645  C C    . PRO   A 1 46  ? 20.32757 -5.80123  23.62781 1.000 16.31268  ? 43  PRO   A C    1 
ATOM   646  O O    . PRO   A 1 46  ? 19.70145 -6.80498  23.96151 1.000 6.96725   ? 43  PRO   A O    1 
ATOM   647  C CB   . PRO   A 1 46  ? 19.20337 -3.81324  24.68897 1.000 17.03052  ? 43  PRO   A CB   1 
ATOM   648  C CG   . PRO   A 1 46  ? 17.83189 -3.19749  24.42298 1.000 27.97484  ? 43  PRO   A CG   1 
ATOM   649  C CD   . PRO   A 1 46  ? 17.16221 -4.13384  23.44013 1.000 28.53376  ? 43  PRO   A CD   1 
ATOM   650  H HA   . PRO   A 1 46  ? 20.16624 -3.90106  22.84504 1.000 13.33236  ? 43  PRO   A HA   1 
ATOM   651  H HB2  . PRO   A 1 46  ? 19.15513 -4.47530  25.39626 1.000 20.52221  ? 43  PRO   A HB2  1 
ATOM   652  H HB3  . PRO   A 1 46  ? 19.85207 -3.12950  24.91826 1.000 20.52221  ? 43  PRO   A HB3  1 
ATOM   653  H HG2  . PRO   A 1 46  ? 17.32756 -3.14516  25.24991 1.000 33.65539  ? 43  PRO   A HG2  1 
ATOM   654  H HG3  . PRO   A 1 46  ? 17.93611 -2.31183  24.04134 1.000 33.65539  ? 43  PRO   A HG3  1 
ATOM   655  H HD2  . PRO   A 1 46  ? 16.67988 -4.83696  23.90261 1.000 34.32609  ? 43  PRO   A HD2  1 
ATOM   656  H HD3  . PRO   A 1 46  ? 16.56075 -3.64986  22.85284 1.000 34.32609  ? 43  PRO   A HD3  1 
ATOM   657  N N    . VAL   A 1 47  ? 21.66671 -5.76031  23.55590 1.000 7.44602   ? 44  VAL   A N    1 
ATOM   658  C CA   . VAL   A 1 47  ? 22.53341 -6.94023  23.60135 1.000 3.20450   ? 44  VAL   A CA   1 
ATOM   659  C C    . VAL   A 1 47  ? 23.34451 -6.92902  24.89046 1.000 6.01541   ? 44  VAL   A C    1 
ATOM   660  O O    . VAL   A 1 47  ? 24.01219 -5.94130  25.19384 1.000 8.68336   ? 44  VAL   A O    1 
ATOM   661  C CB   . VAL   A 1 47  ? 23.47234 -6.96233  22.37967 1.000 4.54421   ? 44  VAL   A CB   1 
ATOM   662  C CG1  . VAL   A 1 47  ? 24.45902 -8.14399  22.46098 1.000 10.94353  ? 44  VAL   A CG1  1 
ATOM   663  C CG2  . VAL   A 1 47  ? 22.67352 -7.02513  21.07652 1.000 16.54564  ? 44  VAL   A CG2  1 
ATOM   664  H H    . VAL   A 1 47  ? 22.11063 -5.02795  23.47725 1.000 9.02080   ? 44  VAL   A H    1 
ATOM   665  H HA   . VAL   A 1 47  ? 21.98085 -7.73742  23.60930 1.000 3.93099   ? 44  VAL   A HA   1 
ATOM   666  H HB   . VAL   A 1 47  ? 23.98637 -6.13972  22.38060 1.000 5.53864   ? 44  VAL   A HB   1 
ATOM   667  H HG11 . VAL   A 1 47  ? 24.81500 -8.31965  21.57592 1.000 13.21782  ? 44  VAL   A HG11 1 
ATOM   668  H HG12 . VAL   A 1 47  ? 25.17978 -7.91242  23.06744 1.000 13.21782  ? 44  VAL   A HG12 1 
ATOM   669  H HG13 . VAL   A 1 47  ? 23.98868 -8.92611  22.78956 1.000 13.21782  ? 44  VAL   A HG13 1 
ATOM   670  H HG21 . VAL   A 1 47  ? 23.28925 -7.11885  20.33288 1.000 19.94035  ? 44  VAL   A HG21 1 
ATOM   671  H HG22 . VAL   A 1 47  ? 22.07560 -7.78823  21.10909 1.000 19.94035  ? 44  VAL   A HG22 1 
ATOM   672  H HG23 . VAL   A 1 47  ? 22.16101 -6.20719  20.98054 1.000 19.94035  ? 44  VAL   A HG23 1 
ATOM   673  N N    . GLN   A 1 48  ? 23.27648 -8.02377  25.64384 1.000 7.93390   ? 45  GLN   A N    1 
ATOM   674  C CA   . GLN   A 1 48  ? 23.99532 -8.16866  26.90108 1.000 8.01975   ? 45  GLN   A CA   1 
ATOM   675  C C    . GLN   A 1 48  ? 25.36051 -8.74832  26.58488 1.000 8.43281   ? 45  GLN   A C    1 
ATOM   676  O O    . GLN   A 1 48  ? 25.46833 -9.90542  26.17914 1.000 5.16121   ? 45  GLN   A O    1 
ATOM   677  C CB   . GLN   A 1 48  ? 23.22380 -9.06447  27.87271 1.000 14.57184  ? 45  GLN   A CB   1 
ATOM   678  C CG   . GLN   A 1 48  ? 23.90461 -9.24870  29.22049 1.000 25.64951  ? 45  GLN   A CG   1 
ATOM   679  C CD   . GLN   A 1 48  ? 23.10132 -10.12451 30.17586 1.000 35.47438  ? 45  GLN   A CD   1 
ATOM   680  O OE1  . GLN   A 1 48  ? 22.45014 -11.08769 29.75989 1.000 30.49089  ? 45  GLN   A OE1  1 
ATOM   681  N NE2  . GLN   A 1 48  ? 23.13625 -9.78380  31.46055 1.000 40.47657  ? 45  GLN   A NE2  1 
ATOM   682  H H    . GLN   A 1 48  ? 22.80650 -8.71456  25.44004 1.000 9.60626   ? 45  GLN   A H    1 
ATOM   683  H HA   . GLN   A 1 48  ? 24.10483 -7.30163  27.32199 1.000 9.70928   ? 45  GLN   A HA   1 
ATOM   684  H HB2  . GLN   A 1 48  ? 22.35256 -8.66973  28.03401 1.000 17.57179  ? 45  GLN   A HB2  1 
ATOM   685  H HB3  . GLN   A 1 48  ? 23.12144 -9.94178  27.47175 1.000 17.57179  ? 45  GLN   A HB3  1 
ATOM   686  H HG2  . GLN   A 1 48  ? 24.76791 -9.66910  29.08314 1.000 30.86500  ? 45  GLN   A HG2  1 
ATOM   687  H HG3  . GLN   A 1 48  ? 24.02096 -8.38025  29.63662 1.000 30.86500  ? 45  GLN   A HG3  1 
ATOM   688  H HE21 . GLN   A 1 48  ? 23.59524 -9.10142  31.71212 1.000 48.65747  ? 45  GLN   A HE21 1 
ATOM   689  H HE22 . GLN   A 1 48  ? 22.69987 -10.24581 32.03997 1.000 48.65747  ? 45  GLN   A HE22 1 
ATOM   690  N N    . CYS   A 1 49  ? 26.40297 -7.95540  26.78429 1.000 8.61289   ? 46  CYS   A N    1 
ATOM   691  C CA   . CYS   A 1 49  ? 27.74055 -8.40405  26.47759 1.000 5.36777   ? 46  CYS   A CA   1 
ATOM   692  C C    . CYS   A 1 49  ? 28.30472 -9.24039  27.61505 1.000 7.14466   ? 46  CYS   A C    1 
ATOM   693  O O    . CYS   A 1 49  ? 27.66208 -9.49521  28.63650 1.000 5.84095   ? 46  CYS   A O    1 
ATOM   694  C CB   . CYS   A 1 49  ? 28.62423 -7.20470  26.16279 1.000 4.41265   ? 46  CYS   A CB   1 
ATOM   695  S SG   . CYS   A 1 49  ? 28.05628 -6.39721  24.68267 1.000 8.42236   ? 46  CYS   A SG   1 
ATOM   696  H H    . CYS   A 1 49  ? 26.35671 -7.15522  27.09600 1.000 10.42106  ? 46  CYS   A H    1 
ATOM   697  H HA   . CYS   A 1 49  ? 27.70907 -8.97400  25.69333 1.000 6.52691   ? 46  CYS   A HA   1 
ATOM   698  H HB2  . CYS   A 1 49  ? 28.58742 -6.57156  26.89673 1.000 5.38077   ? 46  CYS   A HB2  1 
ATOM   699  H HB3  . CYS   A 1 49  ? 29.53774 -7.50048  26.02529 1.000 5.38077   ? 46  CYS   A HB3  1 
ATOM   700  H HG   . CYS   A 1 49  ? 28.77554 -5.46658  24.44478 1.000 10.19242  ? 46  CYS   A HG   1 
ATOM   701  N N    . SER   A 1 50  ? 29.53570 -9.69384  27.41407 1.000 4.94421   ? 47  SER   A N    1 
ATOM   702  C CA   . SER   A 1 50  ? 30.08639 -10.73969 28.27372 1.000 4.47637   ? 47  SER   A CA   1 
ATOM   703  C C    . SER   A 1 50  ? 30.23095 -10.26616 29.70905 1.000 4.08823   ? 47  SER   A C    1 
ATOM   704  O O    . SER   A 1 50  ? 30.09749 -11.06593 30.64443 1.000 3.87438   ? 47  SER   A O    1 
ATOM   705  C CB   . SER   A 1 50  ? 31.44715 -11.20788 27.73927 1.000 6.15385   ? 47  SER   A CB   1 
ATOM   706  O OG   . SER   A 1 50  ? 32.44522 -10.17125 27.83986 1.000 6.53835   ? 47  SER   A OG   1 
ATOM   707  H H    . SER   A 1 50  ? 30.06785 -9.41908  26.79688 1.000 6.01864   ? 47  SER   A H    1 
ATOM   708  H HA   . SER   A 1 50  ? 29.47516 -11.49277 28.26102 1.000 5.45723   ? 47  SER   A HA   1 
ATOM   709  H HB2  . SER   A 1 50  ? 31.73934 -11.97406 28.25743 1.000 7.47020   ? 47  SER   A HB2  1 
ATOM   710  H HB3  . SER   A 1 50  ? 31.34778 -11.45631 26.80691 1.000 7.47020   ? 47  SER   A HB3  1 
ATOM   711  H HG   . SER   A 1 50  ? 32.19941 -9.49304  27.40951 1.000 7.93161   ? 47  SER   A HG   1 
ATOM   712  N N    . ARG   A 1 51  ? 30.59701 -8.99492  29.90946 1.000 1.91832   ? 48  ARG   A N    1 
ATOM   713  C CA   . ARG   A 1 51  ? 30.70208 -8.44269  31.25865 1.000 4.25074   ? 48  ARG   A CA   1 
ATOM   714  C C    . ARG   A 1 51  ? 29.47534 -7.60446  31.63638 1.000 3.51097   ? 48  ARG   A C    1 
ATOM   715  O O    . ARG   A 1 51  ? 29.56756 -6.68155  32.45814 1.000 5.61110   ? 48  ARG   A O    1 
ATOM   716  C CB   . ARG   A 1 51  ? 32.00428 -7.64563  31.41325 1.000 5.14484   ? 48  ARG   A CB   1 
ATOM   717  C CG   . ARG   A 1 51  ? 33.20633 -8.53274  31.88863 1.000 6.09748   ? 48  ARG   A CG   1 
ATOM   718  C CD   . ARG   A 1 51  ? 33.59462 -9.51913  30.79613 1.000 5.72386   ? 48  ARG   A CD   1 
ATOM   719  N NE   . ARG   A 1 51  ? 34.54784 -10.53935 31.21807 1.000 3.28414   ? 48  ARG   A NE   1 
ATOM   720  C CZ   . ARG   A 1 51  ? 35.03017 -11.48523 30.42331 1.000 11.03403  ? 48  ARG   A CZ   1 
ATOM   721  N NH1  . ARG   A 1 51  ? 34.65368 -11.58797 29.16754 1.000 7.18077   ? 48  ARG   A NH1  1 
ATOM   722  N NH2  . ARG   A 1 51  ? 35.89060 -12.36706 30.90977 1.000 8.04219   ? 48  ARG   A NH2  1 
ATOM   723  H H    . ARG   A 1 51  ? 30.78761 -8.43926  29.28136 1.000 2.38757   ? 48  ARG   A H    1 
ATOM   724  H HA   . ARG   A 1 51  ? 30.74657 -9.17487  31.89334 1.000 5.18647   ? 48  ARG   A HA   1 
ATOM   725  H HB2  . ARG   A 1 51  ? 32.23916 -7.25571  30.55669 1.000 6.25940   ? 48  ARG   A HB2  1 
ATOM   726  H HB3  . ARG   A 1 51  ? 31.86943 -6.94534  32.07075 1.000 6.25940   ? 48  ARG   A HB3  1 
ATOM   727  H HG2  . ARG   A 1 51  ? 33.97102 -7.96880  32.08387 1.000 7.40257   ? 48  ARG   A HG2  1 
ATOM   728  H HG3  . ARG   A 1 51  ? 32.95095 -9.03125  32.68058 1.000 7.40257   ? 48  ARG   A HG3  1 
ATOM   729  H HD2  . ARG   A 1 51  ? 32.79441 -9.97434  30.49058 1.000 6.95421   ? 48  ARG   A HD2  1 
ATOM   730  H HD3  . ARG   A 1 51  ? 33.99700 -9.02751  30.06313 1.000 6.95421   ? 48  ARG   A HD3  1 
ATOM   731  H HE   . ARG   A 1 51  ? 34.81452 -10.52671 32.03558 1.000 4.02655   ? 48  ARG   A HE   1 
ATOM   732  H HH11 . ARG   A 1 51  ? 34.08145 -11.03378 28.84346 1.000 8.70251   ? 48  ARG   A HH11 1 
ATOM   733  H HH12 . ARG   A 1 51  ? 34.97969 -12.20936 28.67035 1.000 8.70251   ? 48  ARG   A HH12 1 
ATOM   734  H HH21 . ARG   A 1 51  ? 36.13163 -12.32304 31.73413 1.000 9.73621   ? 48  ARG   A HH21 1 
ATOM   735  H HH22 . ARG   A 1 51  ? 36.20819 -12.98362 30.40125 1.000 9.73621   ? 48  ARG   A HH22 1 
ATOM   736  N N    . ASP   A 1 52  ? 28.31882 -7.92835  31.05261 1.000 4.46693   ? 49  ASP   A N    1 
ATOM   737  C CA   . ASP   A 1 52  ? 26.98753 -7.43701  31.41260 1.000 8.96190   ? 49  ASP   A CA   1 
ATOM   738  C C    . ASP   A 1 52  ? 26.75150 -5.99258  30.99981 1.000 9.81364   ? 49  ASP   A C    1 
ATOM   739  O O    . ASP   A 1 52  ? 25.71428 -5.40632  31.33851 1.000 6.78354   ? 49  ASP   A O    1 
ATOM   740  C CB   . ASP   A 1 52  ? 26.71522 -7.62083  32.90895 1.000 9.27545   ? 49  ASP   A CB   1 
ATOM   741  C CG   . ASP   A 1 52  ? 26.16824 -9.00884  33.23080 1.000 19.16145  ? 49  ASP   A CG   1 
ATOM   742  O OD1  . ASP   A 1 52  ? 25.79965 -9.73543  32.28760 1.000 15.52906  ? 49  ASP   A OD1  1 
ATOM   743  O OD2  . ASP   A 1 52  ? 26.09861 -9.35896  34.42419 1.000 18.97332  ? 49  ASP   A OD2  1 
ATOM   744  H H    . ASP   A 1 52  ? 28.27940 -8.47661  30.39120 1.000 5.44590   ? 49  ASP   A H    1 
ATOM   745  H HA   . ASP   A 1 52  ? 26.33032 -7.96134  30.92881 1.000 10.83987  ? 49  ASP   A HA   1 
ATOM   746  H HB2  . ASP   A 1 52  ? 27.54319 -7.50115  33.39992 1.000 11.21612  ? 49  ASP   A HB2  1 
ATOM   747  H HB3  . ASP   A 1 52  ? 26.06135 -6.96443  33.19618 1.000 11.21612  ? 49  ASP   A HB3  1 
ATOM   748  N N    . VAL   A 1 53  ? 27.67918 -5.39935  30.25997 1.000 5.22940   ? 50  VAL   A N    1 
ATOM   749  C CA   . VAL   A 1 53  ? 27.39745 -4.12687  29.63162 1.000 2.93137   ? 50  VAL   A CA   1 
ATOM   750  C C    . VAL   A 1 53  ? 26.34443 -4.38374  28.56837 1.000 4.84158   ? 50  VAL   A C    1 
ATOM   751  O O    . VAL   A 1 53  ? 26.43324 -5.36479  27.82411 1.000 4.97132   ? 50  VAL   A O    1 
ATOM   752  C CB   . VAL   A 1 53  ? 28.67909 -3.53132  29.03223 1.000 6.24699   ? 50  VAL   A CB   1 
ATOM   753  C CG1  . VAL   A 1 53  ? 28.33403 -2.29703  28.22205 1.000 5.65111   ? 50  VAL   A CG1  1 
ATOM   754  C CG2  . VAL   A 1 53  ? 29.66995 -3.19005  30.12481 1.000 10.14006  ? 50  VAL   A CG2  1 
ATOM   755  H H    . VAL   A 1 53  ? 28.46656 -5.71149  30.11100 1.000 6.36087   ? 50  VAL   A H    1 
ATOM   756  H HA   . VAL   A 1 53  ? 27.05957 -3.48725  30.27785 1.000 3.60323   ? 50  VAL   A HA   1 
ATOM   757  H HB   . VAL   A 1 53  ? 29.09537 -4.18431  28.44810 1.000 7.58197   ? 50  VAL   A HB   1 
ATOM   758  H HG11 . VAL   A 1 53  ? 29.14258 -1.78346  28.06909 1.000 6.86691   ? 50  VAL   A HG11 1 
ATOM   759  H HG12 . VAL   A 1 53  ? 27.95178 -2.57250  27.37417 1.000 6.86691   ? 50  VAL   A HG12 1 
ATOM   760  H HG13 . VAL   A 1 53  ? 27.69213 -1.76389  28.71664 1.000 6.86691   ? 50  VAL   A HG13 1 
ATOM   761  H HG21 . VAL   A 1 53  ? 30.47628 -2.83397  29.71991 1.000 12.25366  ? 50  VAL   A HG21 1 
ATOM   762  H HG22 . VAL   A 1 53  ? 29.27523 -2.52785  30.71353 1.000 12.25366  ? 50  VAL   A HG22 1 
ATOM   763  H HG23 . VAL   A 1 53  ? 29.87841 -3.99475  30.62471 1.000 12.25366  ? 50  VAL   A HG23 1 
ATOM   764  N N    . VAL   A 1 54  ? 25.34250 -3.52280  28.49772 1.000 3.43566   ? 51  VAL   A N    1 
ATOM   765  C CA   . VAL   A 1 54  ? 24.22090 -3.70484  27.58591 1.000 9.56076   ? 51  VAL   A CA   1 
ATOM   766  C C    . VAL   A 1 54  ? 24.26131 -2.58287  26.55019 1.000 8.12508   ? 51  VAL   A C    1 
ATOM   767  O O    . VAL   A 1 54  ? 24.15314 -1.40190  26.89385 1.000 6.09176   ? 51  VAL   A O    1 
ATOM   768  C CB   . VAL   A 1 54  ? 22.87886 -3.73527  28.33767 1.000 10.74166  ? 51  VAL   A CB   1 
ATOM   769  C CG1  . VAL   A 1 54  ? 21.73679 -3.86767  27.31850 1.000 11.17862  ? 51  VAL   A CG1  1 
ATOM   770  C CG2  . VAL   A 1 54  ? 22.84494 -4.85531  29.35924 1.000 10.44193  ? 51  VAL   A CG2  1 
ATOM   771  H H    . VAL   A 1 54  ? 25.28737 -2.81077  28.97687 1.000 4.20838   ? 51  VAL   A H    1 
ATOM   772  H HA   . VAL   A 1 54  ? 24.32196 -4.54694  27.11521 1.000 11.55850  ? 51  VAL   A HA   1 
ATOM   773  H HB   . VAL   A 1 54  ? 22.76333 -2.90881  28.83215 1.000 12.97557  ? 51  VAL   A HB   1 
ATOM   774  H HG11 . VAL   A 1 54  ? 20.92417 -4.11757  27.78551 1.000 13.49993  ? 51  VAL   A HG11 1 
ATOM   775  H HG12 . VAL   A 1 54  ? 21.61257 -3.01608  26.87100 1.000 13.49993  ? 51  VAL   A HG12 1 
ATOM   776  H HG13 . VAL   A 1 54  ? 21.96940 -4.55101  26.67054 1.000 13.49993  ? 51  VAL   A HG13 1 
ATOM   777  H HG21 . VAL   A 1 54  ? 21.96490 -4.88507  29.76613 1.000 12.61590  ? 51  VAL   A HG21 1 
ATOM   778  H HG22 . VAL   A 1 54  ? 23.03143 -5.69590  28.91257 1.000 12.61590  ? 51  VAL   A HG22 1 
ATOM   779  H HG23 . VAL   A 1 54  ? 23.51727 -4.68475  30.03731 1.000 12.61590  ? 51  VAL   A HG23 1 
ATOM   780  N N    . ILE   A 1 55  ? 24.40141 -2.95277  25.28098 1.000 3.06815   ? 52  ILE   A N    1 
ATOM   781  C CA   . ILE   A 1 55  ? 24.55985 -2.01140  24.17740 1.000 3.62254   ? 52  ILE   A CA   1 
ATOM   782  C C    . ILE   A 1 55  ? 23.33862 -2.09548  23.26829 1.000 10.62898  ? 52  ILE   A C    1 
ATOM   783  O O    . ILE   A 1 55  ? 22.88250 -3.19684  22.95278 1.000 8.77961   ? 52  ILE   A O    1 
ATOM   784  C CB   . ILE   A 1 55  ? 25.84546 -2.32490  23.39287 1.000 9.87105   ? 52  ILE   A CB   1 
ATOM   785  C CG1  . ILE   A 1 55  ? 27.06070 -1.99644  24.26112 1.000 11.16676  ? 52  ILE   A CG1  1 
ATOM   786  C CG2  . ILE   A 1 55  ? 25.85942 -1.54756  22.08503 1.000 10.11581  ? 52  ILE   A CG2  1 
ATOM   787  C CD1  . ILE   A 1 55  ? 28.36264 -2.48865  23.69787 1.000 18.63023  ? 52  ILE   A CD1  1 
ATOM   788  H H    . ILE   A 1 55  ? 24.40800 -3.77385  25.02530 1.000 3.76737   ? 52  ILE   A H    1 
ATOM   789  H HA   . ILE   A 1 55  ? 24.60701 -1.10691  24.52464 1.000 4.43263   ? 52  ILE   A HA   1 
ATOM   790  H HB   . ILE   A 1 55  ? 25.87575 -3.26929  23.17355 1.000 11.93084  ? 52  ILE   A HB   1 
ATOM   791  H HG12 . ILE   A 1 55  ? 27.12491 -1.03313  24.35494 1.000 13.48570  ? 52  ILE   A HG12 1 
ATOM   792  H HG13 . ILE   A 1 55  ? 26.94140 -2.40734  25.13165 1.000 13.48570  ? 52  ILE   A HG13 1 
ATOM   793  H HG21 . ILE   A 1 55  ? 26.75952 -1.55383  21.72352 1.000 12.22456  ? 52  ILE   A HG21 1 
ATOM   794  H HG22 . ILE   A 1 55  ? 25.24910 -1.96959  21.46029 1.000 12.22456  ? 52  ILE   A HG22 1 
ATOM   795  H HG23 . ILE   A 1 55  ? 25.57833 -0.63523  22.25690 1.000 12.22456  ? 52  ILE   A HG23 1 
ATOM   796  H HD11 . ILE   A 1 55  ? 29.04728 -2.42392  24.38196 1.000 22.44186  ? 52  ILE   A HD11 1 
ATOM   797  H HD12 . ILE   A 1 55  ? 28.25788 -3.41240  23.42109 1.000 22.44186  ? 52  ILE   A HD12 1 
ATOM   798  H HD13 . ILE   A 1 55  ? 28.60424 -1.94019  22.93516 1.000 22.44186  ? 52  ILE   A HD13 1 
ATOM   799  N N    . CYS   A 1 56  ? 22.83458 -0.93763  22.81385 1.000 6.31673   ? 53  CYS   A N    1 
ATOM   800  C CA   . CYS   A 1 56  ? 21.73994 -0.89753  21.83193 1.000 7.88212   ? 53  CYS   A CA   1 
ATOM   801  C C    . CYS   A 1 56  ? 22.31042 -0.85350  20.41991 1.000 9.66159   ? 53  CYS   A C    1 
ATOM   802  O O    . CYS   A 1 56  ? 23.04711 0.09168   20.08939 1.000 13.46946  ? 53  CYS   A O    1 
ATOM   803  C CB   . CYS   A 1 56  ? 20.85832 0.31681   22.03892 1.000 12.12784  ? 53  CYS   A CB   1 
ATOM   804  S SG   . CYS   A 1 56  ? 19.89187 0.23528   23.49510 1.000 27.67398  ? 53  CYS   A SG   1 
ATOM   805  H H    . CYS   A 1 56  ? 23.11006 -0.16082  23.05936 1.000 7.66567   ? 53  CYS   A H    1 
ATOM   806  H HA   . CYS   A 1 56  ? 21.20179 -1.69783  21.93590 1.000 9.54413   ? 53  CYS   A HA   1 
ATOM   807  H HB2  . CYS   A 1 56  ? 21.42043 1.10508   22.09859 1.000 14.63900  ? 53  CYS   A HB2  1 
ATOM   808  H HB3  . CYS   A 1 56  ? 20.25373 0.39680   21.28461 1.000 14.63900  ? 53  CYS   A HB3  1 
ATOM   809  H HG   . CYS   A 1 56  ? 19.17585 1.19704   23.54314 1.000 33.29436  ? 53  CYS   A HG   1 
ATOM   810  N N    . PRO   A 1 57  ? 22.01275 -1.82933  19.57184 1.000 9.57296   ? 54  PRO   A N    1 
ATOM   811  C CA   A PRO   A 1 57  ? 22.55497 -1.79364  18.20917 0.672 9.30071   ? 54  PRO   A CA   1 
ATOM   812  C CA   B PRO   A 1 57  ? 22.54991 -1.79501  18.20704 0.328 9.29727   ? 54  PRO   A CA   1 
ATOM   813  C C    . PRO   A 1 57  ? 21.86779 -0.71718  17.38465 1.000 5.28357   ? 54  PRO   A C    1 
ATOM   814  O O    . PRO   A 1 57  ? 20.78442 -0.23188  17.71820 1.000 8.21755   ? 54  PRO   A O    1 
ATOM   815  C CB   A PRO   A 1 57  ? 22.26881 -3.19871  17.67487 0.672 8.06511   ? 54  PRO   A CB   1 
ATOM   816  C CB   B PRO   A 1 57  ? 22.24785 -3.19395  17.65744 0.328 8.13865   ? 54  PRO   A CB   1 
ATOM   817  C CG   A PRO   A 1 57  ? 21.04282 -3.63767  18.44607 0.672 12.05507  ? 54  PRO   A CG   1 
ATOM   818  C CG   B PRO   A 1 57  ? 21.95598 -4.03994  18.86042 0.328 9.38576   ? 54  PRO   A CG   1 
ATOM   819  C CD   A PRO   A 1 57  ? 21.15632 -3.00738  19.81545 0.672 10.26665  ? 54  PRO   A CD   1 
ATOM   820  C CD   B PRO   A 1 57  ? 21.34195 -3.10600  19.87363 0.328 10.21848  ? 54  PRO   A CD   1 
ATOM   821  H HA   A PRO   A 1 57  ? 23.51365 -1.64590  18.20641 0.672 11.24644  ? 54  PRO   A HA   1 
ATOM   822  H HA   B PRO   A 1 57  ? 23.50983 -1.65562  18.21087 0.328 11.24231  ? 54  PRO   A HA   1 
ATOM   823  H HB2  A PRO   A 1 57  ? 22.09070 -3.16456  16.72197 0.672 9.76372   ? 54  PRO   A HB2  1 
ATOM   824  H HB2  B PRO   A 1 57  ? 21.47929 -3.15598  17.06686 0.328 9.85197   ? 54  PRO   A HB2  1 
ATOM   825  H HB3  A PRO   A 1 57  ? 23.02240 -3.78357  17.85077 0.672 9.76372   ? 54  PRO   A HB3  1 
ATOM   826  H HB3  B PRO   A 1 57  ? 23.01953 -3.53159  17.17640 0.328 9.85197   ? 54  PRO   A HB3  1 
ATOM   827  H HG2  A PRO   A 1 57  ? 20.24401 -3.32719  17.99175 0.672 14.55167  ? 54  PRO   A HG2  1 
ATOM   828  H HG2  B PRO   A 1 57  ? 21.33516 -4.74616  18.62224 0.328 11.34849  ? 54  PRO   A HG2  1 
ATOM   829  H HG3  A PRO   A 1 57  ? 21.03058 -4.60515  18.51476 0.672 14.55167  ? 54  PRO   A HG3  1 
ATOM   830  H HG3  B PRO   A 1 57  ? 22.77990 -4.42306  19.19997 0.328 11.34849  ? 54  PRO   A HG3  1 
ATOM   831  H HD2  A PRO   A 1 57  ? 20.28479 -2.73907  20.14611 0.672 12.40556  ? 54  PRO   A HD2  1 
ATOM   832  H HD2  B PRO   A 1 57  ? 20.38297 -3.03486  19.74635 0.328 12.34777  ? 54  PRO   A HD2  1 
ATOM   833  H HD3  A PRO   A 1 57  ? 21.57611 -3.61646  20.44292 0.672 12.40556  ? 54  PRO   A HD3  1 
ATOM   834  H HD3  B PRO   A 1 57  ? 21.53586 -3.39663  20.77852 0.328 12.34777  ? 54  PRO   A HD3  1 
ATOM   835  N N    . ASP   A 1 58  ? 22.55130 -0.31437  16.31604 1.000 7.04797   ? 55  ASP   A N    1 
ATOM   836  C CA   . ASP   A 1 58  ? 21.99487 0.66899   15.39148 1.000 8.11511   ? 55  ASP   A CA   1 
ATOM   837  C C    . ASP   A 1 58  ? 20.87316 0.06464   14.54141 1.000 11.72090  ? 55  ASP   A C    1 
ATOM   838  O O    . ASP   A 1 58  ? 19.94361 0.76775   14.12238 1.000 13.56982  ? 55  ASP   A O    1 
ATOM   839  C CB   . ASP   A 1 58  ? 23.09601 1.19076   14.47068 1.000 12.75615  ? 55  ASP   A CB   1 
ATOM   840  C CG   . ASP   A 1 58  ? 24.21406 1.88077   15.21517 1.000 11.95137  ? 55  ASP   A CG   1 
ATOM   841  O OD1  . ASP   A 1 58  ? 23.90496 2.59139   16.15975 1.000 6.96615   ? 55  ASP   A OD1  1 
ATOM   842  O OD2  . ASP   A 1 58  ? 25.39734 1.67988   14.88241 1.000 9.90127   ? 55  ASP   A OD2  1 
ATOM   843  H H    . ASP   A 1 58  ? 23.33654 -0.59345  16.10363 1.000 8.54315   ? 55  ASP   A H    1 
ATOM   844  H HA   . ASP   A 1 58  ? 21.63448 1.40958   15.90387 1.000 9.82371   ? 55  ASP   A HA   1 
ATOM   845  H HB2  . ASP   A 1 58  ? 23.47829 0.44450   13.98298 1.000 15.39296  ? 55  ASP   A HB2  1 
ATOM   846  H HB3  . ASP   A 1 58  ? 22.71124 1.82999   13.85081 1.000 15.39296  ? 55  ASP   A HB3  1 
ATOM   847  N N    . ALA   A 1 59  ? 20.95141 -1.23156  14.27168 1.000 9.10742   ? 56  ALA   A N    1 
ATOM   848  C CA   . ALA   A 1 59  ? 20.01935 -1.89881  13.37247 1.000 19.24088  ? 56  ALA   A CA   1 
ATOM   849  C C    . ALA   A 1 59  ? 20.10921 -3.39979  13.60355 1.000 14.93454  ? 56  ALA   A C    1 
ATOM   850  O O    . ALA   A 1 59  ? 21.07058 -3.89630  14.19409 1.000 15.39255  ? 56  ALA   A O    1 
ATOM   851  C CB   . ALA   A 1 59  ? 20.32993 -1.56500  11.90988 1.000 14.55049  ? 56  ALA   A CB   1 
ATOM   852  H H    A ALA   A 1 59  ? 21.54624 -1.75715  14.60264 0.670 11.01449  ? 56  ALA   A H    1 
ATOM   853  H H    B ALA   A 1 59  ? 21.54624 -1.75715  14.60264 0.330 11.01449  ? 56  ALA   A H    1 
ATOM   854  H HA   . ALA   A 1 59  ? 19.11438 -1.61232  13.57212 1.000 23.17464  ? 56  ALA   A HA   1 
ATOM   855  H HB1  . ALA   A 1 59  ? 19.69617 -2.02698  11.33907 1.000 17.54617  ? 56  ALA   A HB1  1 
ATOM   856  H HB2  . ALA   A 1 59  ? 20.25317 -0.60660  11.78153 1.000 17.54617  ? 56  ALA   A HB2  1 
ATOM   857  H HB3  . ALA   A 1 59  ? 21.23251 -1.85499  11.70457 1.000 17.54617  ? 56  ALA   A HB3  1 
ATOM   858  N N    . SER   A 1 60  ? 19.08934 -4.11866  13.14430 1.000 13.45471  ? 57  SER   A N    1 
ATOM   859  C CA   . SER   A 1 60  ? 19.18700 -5.56946  13.05693 1.000 16.00248  ? 57  SER   A CA   1 
ATOM   860  C C    . SER   A 1 60  ? 20.15072 -5.92554  11.92754 1.000 9.09620   ? 57  SER   A C    1 
ATOM   861  O O    . SER   A 1 60  ? 20.36539 -5.14714  10.98738 1.000 13.16586  ? 57  SER   A O    1 
ATOM   862  C CB   . SER   A 1 60  ? 17.81630 -6.21632  12.79640 1.000 17.07795  ? 57  SER   A CB   1 
ATOM   863  O OG   . SER   A 1 60  ? 17.41559 -5.99078  11.45163 1.000 21.13331  ? 57  SER   A OG   1 
ATOM   864  H H    . SER   A 1 60  ? 18.33840 -3.79333  12.88002 1.000 16.23124  ? 57  SER   A H    1 
ATOM   865  H HA   . SER   A 1 60  ? 19.50930 -5.92974  13.89789 1.000 19.28856  ? 57  SER   A HA   1 
ATOM   866  H HB2  . SER   A 1 60  ? 17.87980 -7.17135  12.95385 1.000 20.57913  ? 57  SER   A HB2  1 
ATOM   867  H HB3  . SER   A 1 60  ? 17.16048 -5.82443  13.39408 1.000 20.57913  ? 57  SER   A HB3  1 
ATOM   868  H HG   . SER   A 1 60  ? 16.70863 -6.41379  11.28772 1.000 25.44556  ? 57  SER   A HG   1 
ATOM   869  N N    . LEU   A 1 61  ? 20.76251 -7.10631  12.04150 1.000 14.62486  ? 58  LEU   A N    1 
ATOM   870  C CA   . LEU   A 1 61  ? 21.61564 -7.58976  10.95800 1.000 11.82049  ? 58  LEU   A CA   1 
ATOM   871  C C    . LEU   A 1 61  ? 20.81149 -7.78941  9.66970  1.000 19.98038  ? 58  LEU   A C    1 
ATOM   872  O O    . LEU   A 1 61  ? 21.29817 -7.50060  8.57084  1.000 13.59283  ? 58  LEU   A O    1 
ATOM   873  C CB   . LEU   A 1 61  ? 22.30393 -8.89192  11.38456 1.000 11.34311  ? 58  LEU   A CB   1 
ATOM   874  C CG   . LEU   A 1 61  ? 23.34491 -9.47949  10.42568 1.000 13.69306  ? 58  LEU   A CG   1 
ATOM   875  C CD1  . LEU   A 1 61  ? 24.46275 -8.48540  10.17186 1.000 16.36544  ? 58  LEU   A CD1  1 
ATOM   876  C CD2  . LEU   A 1 61  ? 23.90386 -10.78068 10.96995 1.000 18.78432  ? 58  LEU   A CD2  1 
ATOM   877  H H    . LEU   A 1 61  ? 20.70143 -7.63298  12.71862 1.000 17.63541  ? 58  LEU   A H    1 
ATOM   878  H HA   . LEU   A 1 61  ? 22.30554 -6.93277  10.77551 1.000 14.27018  ? 58  LEU   A HA   1 
ATOM   879  H HB2  . LEU   A 1 61  ? 22.75683 -8.72747  12.22643 1.000 13.69731  ? 58  LEU   A HB2  1 
ATOM   880  H HB3  . LEU   A 1 61  ? 21.61726 -9.56663  11.50352 1.000 13.69731  ? 58  LEU   A HB3  1 
ATOM   881  H HG   . LEU   A 1 61  ? 22.91366 -9.66978  9.57791  1.000 16.51726  ? 58  LEU   A HG   1 
ATOM   882  H HD11 . LEU   A 1 61  ? 25.26008 -8.96841  9.90379  1.000 19.72411  ? 58  LEU   A HD11 1 
ATOM   883  H HD12 . LEU   A 1 61  ? 24.19100 -7.87801  9.46608  1.000 19.72411  ? 58  LEU   A HD12 1 
ATOM   884  H HD13 . LEU   A 1 61  ? 24.63516 -7.98907  10.98723 1.000 19.72411  ? 58  LEU   A HD13 1 
ATOM   885  H HD21 . LEU   A 1 61  ? 24.51847 -11.15656 10.32043 1.000 22.62677  ? 58  LEU   A HD21 1 
ATOM   886  H HD22 . LEU   A 1 61  ? 24.37028 -10.60083 11.80121 1.000 22.62677  ? 58  LEU   A HD22 1 
ATOM   887  H HD23 . LEU   A 1 61  ? 23.17187 -11.39720 11.12807 1.000 22.62677  ? 58  LEU   A HD23 1 
ATOM   888  N N    . GLU   A 1 62  ? 19.56503 -8.25591  9.78852  1.000 23.07530  ? 59  GLU   A N    1 
ATOM   889  C CA   . GLU   A 1 62  ? 18.70695 -8.41473  8.61604  1.000 31.41093  ? 59  GLU   A CA   1 
ATOM   890  C C    . GLU   A 1 62  ? 18.58221 -7.10632  7.84185  1.000 13.54286  ? 59  GLU   A C    1 
ATOM   891  O O    . GLU   A 1 62  ? 18.72372 -7.07966  6.61762  1.000 30.88858  ? 59  GLU   A O    1 
ATOM   892  C CB   . GLU   A 1 62  ? 17.33423 -8.91225  9.06007  1.000 27.24053  ? 59  GLU   A CB   1 
ATOM   893  C CG   . GLU   A 1 62  ? 16.46861 -9.42617  7.93193  1.000 64.64581  ? 59  GLU   A CG   1 
ATOM   894  C CD   . GLU   A 1 62  ? 15.05094 -9.70999  8.39020  1.000 76.11202  ? 59  GLU   A CD   1 
ATOM   895  O OE1  . GLU   A 1 62  ? 14.79434 -9.70623  9.62694  1.000 53.88302  ? 59  GLU   A OE1  1 
ATOM   896  O OE2  . GLU   A 1 62  ? 14.19587 -9.92339  7.50555  1.000 82.18277  ? 59  GLU   A OE2  1 
ATOM   897  H H    . GLU   A 1 62  ? 19.19647 -8.48537  10.53088 1.000 27.77594  ? 59  GLU   A H    1 
ATOM   898  H HA   . GLU   A 1 62  ? 19.09782 -9.07355  8.02099  1.000 37.77870  ? 59  GLU   A HA   1 
ATOM   899  H HB2  . GLU   A 1 62  ? 17.45658 -9.63818  9.69171  1.000 32.77423  ? 59  GLU   A HB2  1 
ATOM   900  H HB3  . GLU   A 1 62  ? 16.86086 -8.17957  9.48434  1.000 32.77423  ? 59  GLU   A HB3  1 
ATOM   901  H HG2  . GLU   A 1 62  ? 16.43235 -8.75963  7.22815  1.000 77.66055  ? 59  GLU   A HG2  1 
ATOM   902  H HG3  . GLU   A 1 62  ? 16.84745 -10.25060 7.58885  1.000 77.66055  ? 59  GLU   A HG3  1 
ATOM   903  N N    . ASP   A 1 63  ? 18.35764 -5.99894  8.54689  1.000 18.75008  ? 60  ASP   A N    1 
ATOM   904  C CA   . ASP   A 1 63  ? 18.23635 -4.70616  7.87454  1.000 22.17113  ? 60  ASP   A CA   1 
ATOM   905  C C    . ASP   A 1 63  ? 19.58585 -4.21537  7.37591  1.000 25.85464  ? 60  ASP   A C    1 
ATOM   906  O O    . ASP   A 1 63  ? 19.70458 -3.72609  6.24697  1.000 22.41465  ? 60  ASP   A O    1 
ATOM   907  C CB   . ASP   A 1 63  ? 17.62100 -3.67248  8.81918  1.000 22.62760  ? 60  ASP   A CB   1 
ATOM   908  C CG   . ASP   A 1 63  ? 16.15215 -3.95369  9.11138  1.000 24.80920  ? 60  ASP   A CG   1 
ATOM   909  O OD1  . ASP   A 1 63  ? 15.57355 -4.83803  8.45094  1.000 36.28565  ? 60  ASP   A OD1  1 
ATOM   910  O OD2  . ASP   A 1 63  ? 15.58310 -3.28899  9.99577  1.000 36.30684  ? 60  ASP   A OD2  1 
ATOM   911  H H    A ASP   A 1 63  ? 18.27268 -5.96808  9.40213  0.610 22.58568  ? 60  ASP   A H    1 
ATOM   912  H H    B ASP   A 1 63  ? 18.27268 -5.96808  9.40213  0.390 22.58568  ? 60  ASP   A H    1 
ATOM   913  H HA   . ASP   A 1 63  ? 17.64664 -4.81423  7.11200  1.000 26.69094  ? 60  ASP   A HA   1 
ATOM   914  H HB2  . ASP   A 1 63  ? 18.10335 -3.68473  9.66066  1.000 27.23871  ? 60  ASP   A HB2  1 
ATOM   915  H HB3  . ASP   A 1 63  ? 17.68461 -2.79388  8.41308  1.000 27.23871  ? 60  ASP   A HB3  1 
ATOM   916  N N    . ALA   A 1 64  ? 20.61035 -4.29714  8.22420  1.000 19.54152  ? 61  ALA   A N    1 
ATOM   917  C CA   . ALA   A 1 64  ? 21.93149 -3.85253  7.80831  1.000 21.77767  ? 61  ALA   A CA   1 
ATOM   918  C C    . ALA   A 1 64  ? 22.42082 -4.64982  6.61133  1.000 12.55936  ? 61  ALA   A C    1 
ATOM   919  O O    . ALA   A 1 64  ? 23.17631 -4.13398  5.78697  1.000 22.18838  ? 61  ALA   A O    1 
ATOM   920  C CB   . ALA   A 1 64  ? 22.91492 -3.97665  8.97347  1.000 20.55570  ? 61  ALA   A CB   1 
ATOM   921  H H    . ALA   A 1 64  ? 20.56537 -4.59992  9.02788  1.000 23.53541  ? 61  ALA   A H    1 
ATOM   922  H HA   . ALA   A 1 64  ? 21.89040 -2.91724  7.55445  1.000 26.21879  ? 61  ALA   A HA   1 
ATOM   923  H HB1  . ALA   A 1 64  ? 23.78009 -3.63874  8.69386  1.000 24.75242  ? 61  ALA   A HB1  1 
ATOM   924  H HB2  . ALA   A 1 64  ? 22.58361 -3.45768  9.72301  1.000 24.75242  ? 61  ALA   A HB2  1 
ATOM   925  H HB3  . ALA   A 1 64  ? 22.99010 -4.91041  9.22516  1.000 24.75242  ? 61  ALA   A HB3  1 
ATOM   926  N N    . LYS   A 1 65  ? 22.04281 -5.92380  6.52937  1.000 21.42960  ? 62  LYS   A N    1 
ATOM   927  C CA   . LYS   A 1 65  ? 22.42637 -6.74090  5.38138  1.000 24.44229  ? 62  LYS   A CA   1 
ATOM   928  C C    . LYS   A 1 65  ? 22.01235 -6.07879  4.07438  1.000 40.68097  ? 62  LYS   A C    1 
ATOM   929  O O    . LYS   A 1 65  ? 22.72978 -6.16072  3.07149  1.000 33.68492  ? 62  LYS   A O    1 
ATOM   930  C CB   . LYS   A 1 65  ? 21.78616 -8.12962  5.49863  1.000 37.09237  ? 62  LYS   A CB   1 
ATOM   931  C CG   . LYS   A 1 65  ? 22.09208 -9.09501  4.35489  1.000 49.40082  ? 62  LYS   A CG   1 
ATOM   932  C CD   . LYS   A 1 65  ? 21.02777 -10.21490 4.23603  1.000 73.55605  ? 62  LYS   A CD   1 
ATOM   933  C CE   . LYS   A 1 65  ? 20.98522 -11.14134 5.45145  1.000 55.01580  ? 62  LYS   A CE   1 
ATOM   934  N NZ   . LYS   A 1 65  ? 22.19915 -12.01193 5.53773  1.000 73.59406  ? 62  LYS   A NZ   1 
ATOM   935  H H    . LYS   A 1 65  ? 21.56936 -6.33500  7.11789  1.000 25.80110  ? 62  LYS   A H    1 
ATOM   936  H HA   . LYS   A 1 65  ? 23.39048 -6.84754  5.37574  1.000 29.41633  ? 62  LYS   A HA   1 
ATOM   937  H HB2  . LYS   A 1 65  ? 22.10234 -8.54287  6.31726  1.000 44.59643  ? 62  LYS   A HB2  1 
ATOM   938  H HB3  . LYS   A 1 65  ? 20.82307 -8.01932  5.53319  1.000 44.59643  ? 62  LYS   A HB3  1 
ATOM   939  H HG2  . LYS   A 1 65  ? 22.10853 -8.60374  3.51866  1.000 59.36657  ? 62  LYS   A HG2  1 
ATOM   940  H HG3  . LYS   A 1 65  ? 22.95362 -9.51227  4.51154  1.000 59.36657  ? 62  LYS   A HG3  1 
ATOM   941  H HD2  . LYS   A 1 65  ? 20.15236 -9.80782  4.14200  1.000 88.35285  ? 62  LYS   A HD2  1 
ATOM   942  H HD3  . LYS   A 1 65  ? 21.22722 -10.75657 3.45647  1.000 88.35285  ? 62  LYS   A HD3  1 
ATOM   943  H HE2  . LYS   A 1 65  ? 20.93873 -10.60602 6.25903  1.000 66.10455  ? 62  LYS   A HE2  1 
ATOM   944  H HE3  . LYS   A 1 65  ? 20.20545 -11.71480 5.38821  1.000 66.10455  ? 62  LYS   A HE3  1 
ATOM   945  H HZ1  . LYS   A 1 65  ? 22.14604 -12.53825 6.25346  1.000 88.39846  ? 62  LYS   A HZ1  1 
ATOM   946  H HZ2  . LYS   A 1 65  ? 22.26178 -12.51995 4.80965  1.000 88.39846  ? 62  LYS   A HZ2  1 
ATOM   947  H HZ3  . LYS   A 1 65  ? 22.93049 -11.50892 5.60273  1.000 88.39846  ? 62  LYS   A HZ3  1 
ATOM   948  N N    . LYS   A 1 66  ? 20.86070 -5.40673  4.07213  1.000 35.27298  ? 63  LYS   A N    1 
ATOM   949  C CA   . LYS   A 1 66  ? 20.30335 -4.82971  2.85536  1.000 48.02921  ? 63  LYS   A CA   1 
ATOM   950  C C    . LYS   A 1 66  ? 20.91056 -3.47719  2.50327  1.000 39.09116  ? 63  LYS   A C    1 
ATOM   951  O O    . LYS   A 1 66  ? 20.59825 -2.93921  1.43789  1.000 44.37373  ? 63  LYS   A O    1 
ATOM   952  C CB   . LYS   A 1 66  ? 18.77533 -4.68154  2.98955  1.000 35.44079  ? 63  LYS   A CB   1 
ATOM   953  C CG   . LYS   A 1 66  ? 18.02217 -5.98088  3.33176  1.000 44.50661  ? 63  LYS   A CG   1 
ATOM   954  C CD   . LYS   A 1 66  ? 16.58007 -5.68129  3.78574  1.000 47.13866  ? 63  LYS   A CD   1 
ATOM   955  C CE   . LYS   A 1 66  ? 15.83626 -6.95216  4.20401  1.000 60.61372  ? 63  LYS   A CE   1 
ATOM   956  N NZ   . LYS   A 1 66  ? 15.62360 -7.89173  3.06688  1.000 63.95191  ? 63  LYS   A NZ   1 
ATOM   957  H H    . LYS   A 1 66  ? 20.37946 -5.27098  4.77183  1.000 42.41316  ? 63  LYS   A H    1 
ATOM   958  H HA   . LYS   A 1 66  ? 20.48299 -5.43676  2.12043  1.000 57.72064  ? 63  LYS   A HA   1 
ATOM   959  H HB2  . LYS   A 1 66  ? 18.58979 -4.04330  3.69604  1.000 42.61454  ? 63  LYS   A HB2  1 
ATOM   960  H HB3  . LYS   A 1 66  ? 18.42350 -4.35498  2.14665  1.000 42.61454  ? 63  LYS   A HB3  1 
ATOM   961  H HG2  . LYS   A 1 66  ? 17.98481 -6.54905  2.54646  1.000 53.49351  ? 63  LYS   A HG2  1 
ATOM   962  H HG3  . LYS   A 1 66  ? 18.48139 -6.44033  4.05212  1.000 53.49351  ? 63  LYS   A HG3  1 
ATOM   963  H HD2  . LYS   A 1 66  ? 16.60290 -5.07946  4.54612  1.000 56.65197  ? 63  LYS   A HD2  1 
ATOM   964  H HD3  . LYS   A 1 66  ? 16.09293 -5.27227  3.05342  1.000 56.65197  ? 63  LYS   A HD3  1 
ATOM   965  H HE2  . LYS   A 1 66  ? 16.35390 -7.41366  4.88222  1.000 72.82205  ? 63  LYS   A HE2  1 
ATOM   966  H HE3  . LYS   A 1 66  ? 14.96702 -6.70838  4.55885  1.000 72.82205  ? 63  LYS   A HE3  1 
ATOM   967  H HZ1  . LYS   A 1 66  ? 15.14762 -8.59361  3.33688  1.000 76.82788  ? 63  LYS   A HZ1  1 
ATOM   968  H HZ2  . LYS   A 1 66  ? 15.18524 -7.48075  2.41034  1.000 76.82788  ? 63  LYS   A HZ2  1 
ATOM   969  H HZ3  . LYS   A 1 66  ? 16.40765 -8.17653  2.75663  1.000 76.82788  ? 63  LYS   A HZ3  1 
ATOM   970  N N    . GLU   A 1 67  ? 21.75525 -2.90642  3.36116  1.000 33.58902  ? 64  GLU   A N    1 
ATOM   971  C CA   . GLU   A 1 67  ? 22.34041 -1.58915  3.12025  1.000 29.62582  ? 64  GLU   A CA   1 
ATOM   972  C C    . GLU   A 1 67  ? 23.83831 -1.66481  2.82913  1.000 28.13773  ? 64  GLU   A C    1 
ATOM   973  O O    . GLU   A 1 67  ? 24.56094 -0.66933  2.98027  1.000 35.34036  ? 64  GLU   A O    1 
ATOM   974  C CB   . GLU   A 1 67  ? 22.06731 -0.67327  4.31060  1.000 34.79686  ? 64  GLU   A CB   1 
ATOM   975  C CG   . GLU   A 1 67  ? 20.58047 -0.52026  4.60147  1.000 50.89752  ? 64  GLU   A CG   1 
ATOM   976  C CD   . GLU   A 1 67  ? 20.30047 0.37821   5.78675  1.000 70.25833  ? 64  GLU   A CD   1 
ATOM   977  O OE1  . GLU   A 1 67  ? 20.84348 0.12255   6.88751  1.000 69.33007  ? 64  GLU   A OE1  1 
ATOM   978  O OE2  . GLU   A 1 67  ? 19.53863 1.34992   5.61129  1.000 74.26922  ? 64  GLU   A OE2  1 
ATOM   979  H H    A GLU   A 1 67  ? 22.00765 -3.26791  4.09955  0.592 40.39241  ? 64  GLU   A H    1 
ATOM   980  H H    B GLU   A 1 67  ? 22.00765 -3.26791  4.09955  0.408 40.39241  ? 64  GLU   A H    1 
ATOM   981  H HA   . GLU   A 1 67  ? 21.91707 -1.19829  2.33992  1.000 35.63656  ? 64  GLU   A HA   1 
ATOM   982  H HB2  . GLU   A 1 67  ? 22.49184 -1.04489  5.09963  1.000 41.84182  ? 64  GLU   A HB2  1 
ATOM   983  H HB3  . GLU   A 1 67  ? 22.42945 0.20668   4.12234  1.000 41.84182  ? 64  GLU   A HB3  1 
ATOM   984  H HG2  . GLU   A 1 67  ? 20.14519 -0.13522  3.82483  1.000 61.16260  ? 64  GLU   A HG2  1 
ATOM   985  H HG3  . GLU   A 1 67  ? 20.20508 -1.39391  4.79309  1.000 61.16260  ? 64  GLU   A HG3  1 
ATOM   986  N N    . GLY   A 1 68  ? 24.31718 -2.82744  2.40269  1.000 31.07629  ? 65  GLY   A N    1 
ATOM   987  C CA   . GLY   A 1 68  ? 25.70030 -2.98233  2.02509  1.000 37.45729  ? 65  GLY   A CA   1 
ATOM   988  C C    . GLY   A 1 68  ? 25.99826 -2.32701  0.69800  1.000 41.24047  ? 65  GLY   A C    1 
ATOM   989  O O    . GLY   A 1 68  ? 25.17908 -1.57856  0.15532  1.000 52.63346  ? 65  GLY   A O    1 
ATOM   990  H H    . GLY   A 1 68  ? 23.84980 -3.54516  2.32496  1.000 37.37714  ? 65  GLY   A H    1 
ATOM   991  H HA2  . GLY   A 1 68  ? 26.26688 -2.57928  2.70144  1.000 45.03433  ? 65  GLY   A HA2  1 
ATOM   992  H HA3  . GLY   A 1 68  ? 25.91273 -3.92631  1.95676  1.000 45.03433  ? 65  GLY   A HA3  1 
ATOM   993  N N    . PRO   A 1 69  ? 27.19640 -2.58882  0.15185  1.000 51.03366  ? 66  PRO   A N    1 
ATOM   994  C CA   . PRO   A 1 69  ? 28.26326 -3.42164  0.71741  1.000 37.05417  ? 66  PRO   A CA   1 
ATOM   995  C C    . PRO   A 1 69  ? 29.07791 -2.59152  1.68461  1.000 26.90190  ? 66  PRO   A C    1 
ATOM   996  O O    . PRO   A 1 69  ? 29.05650 -1.35284  1.67397  1.000 26.81303  ? 66  PRO   A O    1 
ATOM   997  C CB   . PRO   A 1 69  ? 29.07075 -3.83222  -0.51451 1.000 40.38845  ? 66  PRO   A CB   1 
ATOM   998  C CG   . PRO   A 1 69  ? 29.01615 -2.56789  -1.37503 1.000 53.40357  ? 66  PRO   A CG   1 
ATOM   999  C CD   . PRO   A 1 69  ? 27.63846 -1.93955  -1.09959 1.000 51.23568  ? 66  PRO   A CD   1 
ATOM   1000 H HA   . PRO   A 1 69  ? 27.92259 -4.22591  1.13930  1.000 44.55059  ? 66  PRO   A HA   1 
ATOM   1001 H HB2  . PRO   A 1 69  ? 29.98129 -4.05628  -0.26628 1.000 48.55173  ? 66  PRO   A HB2  1 
ATOM   1002 H HB3  . PRO   A 1 69  ? 28.65336 -4.58591  -0.96019 1.000 48.55173  ? 66  PRO   A HB3  1 
ATOM   1003 H HG2  . PRO   A 1 69  ? 29.72890 -1.96333  -1.11541 1.000 64.16987  ? 66  PRO   A HG2  1 
ATOM   1004 H HG3  . PRO   A 1 69  ? 29.10625 -2.80427  -2.31146 1.000 64.16987  ? 66  PRO   A HG3  1 
ATOM   1005 H HD2  . PRO   A 1 69  ? 27.71691 -0.98027  -0.97912 1.000 61.56840  ? 66  PRO   A HD2  1 
ATOM   1006 H HD3  . PRO   A 1 69  ? 27.02212 -2.13376  -1.82299 1.000 61.56840  ? 66  PRO   A HD3  1 
ATOM   1007 N N    . TYR   A 1 70  ? 29.83352 -3.28557  2.51637  1.000 17.85399  ? 67  TYR   A N    1 
ATOM   1008 C CA   . TYR   A 1 70  ? 30.69485 -2.66662  3.50527  1.000 13.91498  ? 67  TYR   A CA   1 
ATOM   1009 C C    . TYR   A 1 70  ? 32.15127 -2.86927  3.12530  1.000 8.42868   ? 67  TYR   A C    1 
ATOM   1010 O O    . TYR   A 1 70  ? 32.52396 -3.90597  2.58251  1.000 12.19596  ? 67  TYR   A O    1 
ATOM   1011 C CB   . TYR   A 1 70  ? 30.37625 -3.26046  4.88210  1.000 8.89574   ? 67  TYR   A CB   1 
ATOM   1012 C CG   . TYR   A 1 70  ? 28.95499 -2.98614  5.32047  1.000 12.72183  ? 67  TYR   A CG   1 
ATOM   1013 C CD1  . TYR   A 1 70  ? 28.63254 -1.84803  6.01491  1.000 11.48936  ? 67  TYR   A CD1  1 
ATOM   1014 C CD2  . TYR   A 1 70  ? 27.93878 -3.85840  5.01947  1.000 13.78033  ? 67  TYR   A CD2  1 
ATOM   1015 C CE1  . TYR   A 1 70  ? 27.32394 -1.58879  6.39930  1.000 11.25361  ? 67  TYR   A CE1  1 
ATOM   1016 C CE2  . TYR   A 1 70  ? 26.64451 -3.61755  5.40452  1.000 13.03729  ? 67  TYR   A CE2  1 
ATOM   1017 C CZ   . TYR   A 1 70  ? 26.33489 -2.47071  6.08997  1.000 17.54390  ? 67  TYR   A CZ   1 
ATOM   1018 O OH   . TYR   A 1 70  ? 25.04212 -2.22054  6.48211  1.000 21.00760  ? 67  TYR   A OH   1 
ATOM   1019 H H    . TYR   A 1 70  ? 29.86520 -4.14492  2.52723  1.000 21.51037  ? 67  TYR   A H    1 
ATOM   1020 H HA   . TYR   A 1 70  ? 30.55824 -1.70714  3.54582  1.000 16.78356  ? 67  TYR   A HA   1 
ATOM   1021 H HB2  . TYR   A 1 70  ? 30.50015 -4.22191  4.84797  1.000 10.76047  ? 67  TYR   A HB2  1 
ATOM   1022 H HB3  . TYR   A 1 70  ? 30.97408 -2.87205  5.53985  1.000 10.76047  ? 67  TYR   A HB3  1 
ATOM   1023 H HD1  . TYR   A 1 70  ? 29.30179 -1.23981  6.23189  1.000 13.87281  ? 67  TYR   A HD1  1 
ATOM   1024 H HD2  . TYR   A 1 70  ? 28.13280 -4.63263  4.54216  1.000 16.62198  ? 67  TYR   A HD2  1 
ATOM   1025 H HE1  . TYR   A 1 70  ? 27.12306 -0.81151  6.86874  1.000 13.58992  ? 67  TYR   A HE1  1 
ATOM   1026 H HE2  . TYR   A 1 70  ? 25.97682 -4.23202  5.20076  1.000 15.73033  ? 67  TYR   A HE2  1 
ATOM   1027 H HH   . TYR   A 1 70  ? 24.53519 -2.83130  6.20714  1.000 25.29470  ? 67  TYR   A HH   1 
ATOM   1028 N N    . ASP   A 1 71  ? 32.96326 -1.86332  3.39612  1.000 5.13965   ? 68  ASP   A N    1 
ATOM   1029 C CA   . ASP   A 1 71  ? 34.38490 -1.95858  3.16170  1.000 10.24880  ? 68  ASP   A CA   1 
ATOM   1030 C C    . ASP   A 1 71  ? 35.09935 -2.80609  4.20016  1.000 11.96712  ? 68  ASP   A C    1 
ATOM   1031 O O    . ASP   A 1 71  ? 36.18729 -3.30512  3.90785  1.000 12.97414  ? 68  ASP   A O    1 
ATOM   1032 C CB   . ASP   A 1 71  ? 34.95115 -0.56172  3.13538  1.000 10.14338  ? 68  ASP   A CB   1 
ATOM   1033 C CG   . ASP   A 1 71  ? 34.23447 0.30727   2.13855  1.000 13.85222  ? 68  ASP   A CG   1 
ATOM   1034 O OD1  . ASP   A 1 71  ? 34.46897 0.10778   0.94468  1.000 18.95360  ? 68  ASP   A OD1  1 
ATOM   1035 O OD2  . ASP   A 1 71  ? 33.43683 1.14560   2.55337  1.000 12.13528  ? 68  ASP   A OD2  1 
ATOM   1036 H H    . ASP   A 1 71  ? 32.71066 -1.10763  3.71973  1.000 6.25316   ? 68  ASP   A H    1 
ATOM   1037 H HA   . ASP   A 1 71  ? 34.55451 -2.37871  2.30402  1.000 12.38414  ? 68  ASP   A HA   1 
ATOM   1038 H HB2  . ASP   A 1 71  ? 34.85603 -0.16064  4.01344  1.000 12.25764  ? 68  ASP   A HB2  1 
ATOM   1039 H HB3  . ASP   A 1 71  ? 35.88829 -0.60030  2.88802  1.000 12.25764  ? 68  ASP   A HB3  1 
ATOM   1040 N N    . VAL   A 1 72  ? 34.52529 -2.97432  5.39222  1.000 7.86910   ? 69  VAL   A N    1 
ATOM   1041 C CA   . VAL   A 1 72  ? 35.07073 -3.89864  6.38445  1.000 4.60380   ? 69  VAL   A CA   1 
ATOM   1042 C C    . VAL   A 1 72  ? 33.91776 -4.52471  7.16232  1.000 8.74447   ? 69  VAL   A C    1 
ATOM   1043 O O    . VAL   A 1 72  ? 32.92248 -3.86318  7.47123  1.000 7.15571   ? 69  VAL   A O    1 
ATOM   1044 C CB   . VAL   A 1 72  ? 36.07639 -3.20440  7.32955  1.000 6.92479   ? 69  VAL   A CB   1 
ATOM   1045 C CG1  . VAL   A 1 72  ? 35.40973 -2.09549  8.12438  1.000 8.89906   ? 69  VAL   A CG1  1 
ATOM   1046 C CG2  . VAL   A 1 72  ? 36.72955 -4.25318  8.26114  1.000 6.11226   ? 69  VAL   A CG2  1 
ATOM   1047 H H    . VAL   A 1 72  ? 33.81589 -2.56215  5.65004  1.000 9.52851   ? 69  VAL   A H    1 
ATOM   1048 H HA   . VAL   A 1 72  ? 35.53906 -4.60864  5.91813  1.000 5.61014   ? 69  VAL   A HA   1 
ATOM   1049 H HB   . VAL   A 1 72  ? 36.77493 -2.78884  6.80017  1.000 8.39533   ? 69  VAL   A HB   1 
ATOM   1050 H HG11 . VAL   A 1 72  ? 36.09094 -1.59314  8.59820  1.000 10.76446  ? 69  VAL   A HG11 1 
ATOM   1051 H HG12 . VAL   A 1 72  ? 34.93311 -1.51181  7.51362  1.000 10.76446  ? 69  VAL   A HG12 1 
ATOM   1052 H HG13 . VAL   A 1 72  ? 34.78923 -2.48968  8.75723  1.000 10.76446  ? 69  VAL   A HG13 1 
ATOM   1053 H HG21 . VAL   A 1 72  ? 37.43414 -3.82581  8.77281  1.000 7.42030   ? 69  VAL   A HG21 1 
ATOM   1054 H HG22 . VAL   A 1 72  ? 36.05405 -4.60761  8.86029  1.000 7.42030   ? 69  VAL   A HG22 1 
ATOM   1055 H HG23 . VAL   A 1 72  ? 37.10036 -4.96824  7.72070  1.000 7.42030   ? 69  VAL   A HG23 1 
ATOM   1056 N N    . VAL   A 1 73  ? 34.04299 -5.81211  7.46708  1.000 6.67781   ? 70  VAL   A N    1 
ATOM   1057 C CA   . VAL   A 1 73  ? 33.12472 -6.50082  8.36595  1.000 1.28009   ? 70  VAL   A CA   1 
ATOM   1058 C C    . VAL   A 1 73  ? 33.91703 -6.87145  9.60665  1.000 7.01230   ? 70  VAL   A C    1 
ATOM   1059 O O    . VAL   A 1 73  ? 35.00522 -7.44927  9.49379  1.000 6.47551   ? 70  VAL   A O    1 
ATOM   1060 C CB   . VAL   A 1 73  ? 32.52315 -7.75840  7.72769  1.000 8.03659   ? 70  VAL   A CB   1 
ATOM   1061 C CG1  . VAL   A 1 73  ? 31.65510 -8.49571  8.73993  1.000 5.66731   ? 70  VAL   A CG1  1 
ATOM   1062 C CG2  . VAL   A 1 73  ? 31.67997 -7.35859  6.52465  1.000 8.62353   ? 70  VAL   A CG2  1 
ATOM   1063 H H    . VAL   A 1 73  ? 34.66612 -6.31798  7.15820  1.000 8.09896   ? 70  VAL   A H    1 
ATOM   1064 H HA   . VAL   A 1 73  ? 32.39459 -5.90664  8.59994  1.000 1.62169   ? 70  VAL   A HA   1 
ATOM   1065 H HB   . VAL   A 1 73  ? 33.23615 -8.35011  7.44061  1.000 9.72949   ? 70  VAL   A HB   1 
ATOM   1066 H HG11 . VAL   A 1 73  ? 31.13877 -9.17463  8.27801  1.000 6.88636   ? 70  VAL   A HG11 1 
ATOM   1067 H HG12 . VAL   A 1 73  ? 32.22757 -8.91041  9.40416  1.000 6.88636   ? 70  VAL   A HG12 1 
ATOM   1068 H HG13 . VAL   A 1 73  ? 31.05924 -7.86052  9.16700  1.000 6.88636   ? 70  VAL   A HG13 1 
ATOM   1069 H HG21 . VAL   A 1 73  ? 31.34385 -8.16022  6.09415  1.000 10.43382  ? 70  VAL   A HG21 1 
ATOM   1070 H HG22 . VAL   A 1 73  ? 30.93924 -6.80986  6.82650  1.000 10.43382  ? 70  VAL   A HG22 1 
ATOM   1071 H HG23 . VAL   A 1 73  ? 32.23213 -6.85693  5.90470  1.000 10.43382  ? 70  VAL   A HG23 1 
ATOM   1072 N N    . VAL   A 1 74  ? 33.39381 -6.51218  10.77762 1.000 5.29518   ? 71  VAL   A N    1 
ATOM   1073 C CA   . VAL   A 1 74  ? 34.12992 -6.60407  12.03642 1.000 4.08229   ? 71  VAL   A CA   1 
ATOM   1074 C C    . VAL   A 1 74  ? 33.43953 -7.61173  12.93762 1.000 4.76463   ? 71  VAL   A C    1 
ATOM   1075 O O    . VAL   A 1 74  ? 32.23827 -7.50216  13.19453 1.000 6.03271   ? 71  VAL   A O    1 
ATOM   1076 C CB   . VAL   A 1 74  ? 34.23586 -5.23489  12.72745 1.000 4.63900   ? 71  VAL   A CB   1 
ATOM   1077 C CG1  . VAL   A 1 74  ? 34.97769 -5.39795  14.07649 1.000 9.66754   ? 71  VAL   A CG1  1 
ATOM   1078 C CG2  . VAL   A 1 74  ? 34.96598 -4.24136  11.84127 1.000 6.41218   ? 71  VAL   A CG2  1 
ATOM   1079 H H    . VAL   A 1 74  ? 32.59569 -6.20528  10.86939 1.000 6.43980   ? 71  VAL   A H    1 
ATOM   1080 H HA   . VAL   A 1 74  ? 35.02542 -6.92853  11.85283 1.000 4.98433   ? 71  VAL   A HA   1 
ATOM   1081 H HB   . VAL   A 1 74  ? 33.34541 -4.88726  12.89223 1.000 5.65238   ? 71  VAL   A HB   1 
ATOM   1082 H HG11 . VAL   A 1 74  ? 35.26124 -4.52439  14.38857 1.000 11.68663  ? 71  VAL   A HG11 1 
ATOM   1083 H HG12 . VAL   A 1 74  ? 34.37521 -5.80015  14.72158 1.000 11.68663  ? 71  VAL   A HG12 1 
ATOM   1084 H HG13 . VAL   A 1 74  ? 35.75059 -5.96909  13.94485 1.000 11.68663  ? 71  VAL   A HG13 1 
ATOM   1085 H HG21 . VAL   A 1 74  ? 35.01638 -3.38758  12.29891 1.000 7.78020   ? 71  VAL   A HG21 1 
ATOM   1086 H HG22 . VAL   A 1 74  ? 35.85942 -4.57433  11.66297 1.000 7.78020   ? 71  VAL   A HG22 1 
ATOM   1087 H HG23 . VAL   A 1 74  ? 34.47770 -4.14224  11.00901 1.000 7.78020   ? 71  VAL   A HG23 1 
ATOM   1088 N N    . LEU   A 1 75  ? 34.19833 -8.59848  13.39587 1.000 3.54903   ? 72  LEU   A N    1 
ATOM   1089 C CA   . LEU   A 1 75  ? 33.72004 -9.63471  14.29973 1.000 2.60028   ? 72  LEU   A CA   1 
ATOM   1090 C C    . LEU   A 1 75  ? 34.41463 -9.46359  15.63637 1.000 5.81099   ? 72  LEU   A C    1 
ATOM   1091 O O    . LEU   A 1 75  ? 35.61064 -9.79125  15.75828 1.000 4.90678   ? 72  LEU   A O    1 
ATOM   1092 C CB   . LEU   A 1 75  ? 34.00772 -11.02118 13.73270 1.000 4.12480   ? 72  LEU   A CB   1 
ATOM   1093 C CG   . LEU   A 1 75  ? 33.47938 -11.35494 12.33993 1.000 7.20305   ? 72  LEU   A CG   1 
ATOM   1094 C CD1  . LEU   A 1 75  ? 33.94739 -12.75893 11.97258 1.000 19.37315  ? 72  LEU   A CD1  1 
ATOM   1095 C CD2  . LEU   A 1 75  ? 31.99750 -11.26266 12.36750 1.000 9.01734   ? 72  LEU   A CD2  1 
ATOM   1096 H H    . LEU   A 1 75  ? 35.02772 -8.69330  13.18918 1.000 4.34442   ? 72  LEU   A H    1 
ATOM   1097 H HA   . LEU   A 1 75  ? 32.76140 -9.54679  14.41887 1.000 3.20592   ? 72  LEU   A HA   1 
ATOM   1098 H HB2  . LEU   A 1 75  ? 34.97095 -11.13010 13.69770 1.000 5.03534   ? 72  LEU   A HB2  1 
ATOM   1099 H HB3  . LEU   A 1 75  ? 33.62204 -11.67242 14.33936 1.000 5.03534   ? 72  LEU   A HB3  1 
ATOM   1100 H HG   . LEU   A 1 75  ? 33.80848 -10.74009 11.66572 1.000 8.72925   ? 72  LEU   A HG   1 
ATOM   1101 H HD11 . LEU   A 1 75  ? 33.69863 -12.94437 11.05354 1.000 23.33336  ? 72  LEU   A HD11 1 
ATOM   1102 H HD12 . LEU   A 1 75  ? 34.91129 -12.80618 12.07034 1.000 23.33336  ? 72  LEU   A HD12 1 
ATOM   1103 H HD13 . LEU   A 1 75  ? 33.52301 -13.39854 12.56562 1.000 23.33336  ? 72  LEU   A HD13 1 
ATOM   1104 H HD21 . LEU   A 1 75  ? 31.65074 -11.48690 11.48979 1.000 10.90639  ? 72  LEU   A HD21 1 
ATOM   1105 H HD22 . LEU   A 1 75  ? 31.65455 -11.88520 13.02760 1.000 10.90639  ? 72  LEU   A HD22 1 
ATOM   1106 H HD23 . LEU   A 1 75  ? 31.74181 -10.35701 12.60269 1.000 10.90639  ? 72  LEU   A HD23 1 
ATOM   1107 N N    . PRO   A 1 76  ? 33.72783 -8.94198  16.65546 1.000 9.21425   ? 73  PRO   A N    1 
ATOM   1108 C CA   . PRO   A 1 76  ? 34.32284 -8.87694  17.99278 1.000 4.69705   ? 73  PRO   A CA   1 
ATOM   1109 C C    . PRO   A 1 76  ? 34.52328 -10.26583 18.54812 1.000 4.15655   ? 73  PRO   A C    1 
ATOM   1110 O O    . PRO   A 1 76  ? 34.03403 -11.24852 18.01832 1.000 1.20504   ? 73  PRO   A O    1 
ATOM   1111 C CB   . PRO   A 1 76  ? 33.30005 -8.11066  18.83464 1.000 2.78178   ? 73  PRO   A CB   1 
ATOM   1112 C CG   . PRO   A 1 76  ? 32.35129 -7.50245  17.85920 1.000 10.39000  ? 73  PRO   A CG   1 
ATOM   1113 C CD   . PRO   A 1 76  ? 32.36499 -8.38177  16.63345 1.000 5.59221   ? 73  PRO   A CD   1 
ATOM   1114 H HA   . PRO   A 1 76  ? 35.15717 -8.38278  17.96850 1.000 5.72204   ? 73  PRO   A HA   1 
ATOM   1115 H HB2  . PRO   A 1 76  ? 32.83867 -8.72405  19.42775 1.000 3.42373   ? 73  PRO   A HB2  1 
ATOM   1116 H HB3  . PRO   A 1 76  ? 33.74992 -7.42433  19.35181 1.000 3.42373   ? 73  PRO   A HB3  1 
ATOM   1117 H HG2  . PRO   A 1 76  ? 31.46275 -7.47344  18.24722 1.000 12.55359  ? 73  PRO   A HG2  1 
ATOM   1118 H HG3  . PRO   A 1 76  ? 32.64601 -6.60526  17.63764 1.000 12.55359  ? 73  PRO   A HG3  1 
ATOM   1119 H HD2  . PRO   A 1 76  ? 31.69909 -9.08380  16.70140 1.000 6.79624   ? 73  PRO   A HD2  1 
ATOM   1120 H HD3  . PRO   A 1 76  ? 32.21620 -7.86008  15.82933 1.000 6.79624   ? 73  PRO   A HD3  1 
ATOM   1121 N N    . GLY   A 1 77  ? 35.21394 -10.33074 19.66893 1.000 4.74667   ? 74  GLY   A N    1 
ATOM   1122 C CA   . GLY   A 1 77  ? 35.42782 -11.58247 20.33341 1.000 1.61868   ? 74  GLY   A CA   1 
ATOM   1123 C C    . GLY   A 1 77  ? 34.45678 -11.78445 21.47294 1.000 5.58709   ? 74  GLY   A C    1 
ATOM   1124 O O    . GLY   A 1 77  ? 33.30893 -11.33010 21.42554 1.000 4.31779   ? 74  GLY   A O    1 
ATOM   1125 H H    A GLY   A 1 77  ? 35.56869 -9.65266  20.06130 0.670 5.78159   ? 74  GLY   A H    1 
ATOM   1126 H H    B GLY   A 1 77  ? 35.56869 -9.65266  20.06130 0.330 5.78159   ? 74  GLY   A H    1 
ATOM   1127 H HA2  . GLY   A 1 77  ? 35.31520 -12.30848 19.70007 1.000 2.02800   ? 74  GLY   A HA2  1 
ATOM   1128 H HA3  . GLY   A 1 77  ? 36.33003 -11.61033 20.68858 1.000 2.02800   ? 74  GLY   A HA3  1 
ATOM   1129 N N    . GLY   A 1 78  ? 34.94965 -12.40828 22.53730 1.000 3.36902   ? 75  GLY   A N    1 
ATOM   1130 C CA   . GLY   A 1 78  ? 34.10903 -12.98252 23.57311 1.000 2.83395   ? 75  GLY   A CA   1 
ATOM   1131 C C    . GLY   A 1 78  ? 33.77079 -14.40470 23.16633 1.000 7.45088   ? 75  GLY   A C    1 
ATOM   1132 O O    . GLY   A 1 78  ? 33.31583 -14.63118 22.03959 1.000 7.08629   ? 75  GLY   A O    1 
ATOM   1133 H H    . GLY   A 1 78  ? 35.79035 -12.51381 22.68457 1.000 4.12841   ? 75  GLY   A H    1 
ATOM   1134 H HA2  . GLY   A 1 78  ? 34.57739 -12.99066 24.42251 1.000 3.48632   ? 75  GLY   A HA2  1 
ATOM   1135 H HA3  . GLY   A 1 78  ? 33.29157 -12.46908 23.66815 1.000 3.48632   ? 75  GLY   A HA3  1 
ATOM   1136 N N    . ASN   A 1 79  ? 34.01796 -15.35882 24.06665 1.000 8.66946   ? 76  ASN   A N    1 
ATOM   1137 C CA   . ASN   A 1 79  ? 33.83817 -16.77048 23.73936 1.000 8.66198   ? 76  ASN   A CA   1 
ATOM   1138 C C    . ASN   A 1 79  ? 32.41604 -17.08232 23.30073 1.000 7.73572   ? 76  ASN   A C    1 
ATOM   1139 O O    . ASN   A 1 79  ? 32.21477 -17.71077 22.26062 1.000 8.27580   ? 76  ASN   A O    1 
ATOM   1140 C CB   . ASN   A 1 79  ? 34.23158 -17.63572 24.92629 1.000 14.19240  ? 76  ASN   A CB   1 
ATOM   1141 C CG   . ASN   A 1 79  ? 35.71554 -17.77507 25.04694 1.000 28.63431  ? 76  ASN   A CG   1 
ATOM   1142 O OD1  . ASN   A 1 79  ? 36.43737 -17.65851 24.05322 1.000 32.70916  ? 76  ASN   A OD1  1 
ATOM   1143 N ND2  . ASN   A 1 79  ? 36.19185 -18.02007 26.25363 1.000 26.61030  ? 76  ASN   A ND2  1 
ATOM   1144 H H    . ASN   A 1 79  ? 34.28938 -15.21480 24.86989 1.000 10.48894  ? 76  ASN   A H    1 
ATOM   1145 H HA   . ASN   A 1 79  ? 34.42422 -16.98134 22.99573 1.000 10.47996  ? 76  ASN   A HA   1 
ATOM   1146 H HB2  . ASN   A 1 79  ? 33.89738 -17.23044 25.74174 1.000 17.11647  ? 76  ASN   A HB2  1 
ATOM   1147 H HB3  . ASN   A 1 79  ? 33.85143 -18.52128 24.81598 1.000 17.11647  ? 76  ASN   A HB3  1 
ATOM   1148 H HD21 . ASN   A 1 79  ? 37.03913 -18.10809 26.37178 1.000 32.01794  ? 76  ASN   A HD21 1 
ATOM   1149 H HD22 . ASN   A 1 79  ? 35.65483 -18.09165 26.92153 1.000 32.01794  ? 76  ASN   A HD22 1 
ATOM   1150 N N    . LEU   A 1 80  ? 31.41154 -16.66421 24.07988 1.000 4.58387   ? 77  LEU   A N    1 
ATOM   1151 C CA   . LEU   A 1 80  ? 30.03406 -16.96144 23.70142 1.000 9.21399   ? 77  LEU   A CA   1 
ATOM   1152 C C    . LEU   A 1 80  ? 29.60862 -16.12952 22.49812 1.000 8.78794   ? 77  LEU   A C    1 
ATOM   1153 O O    . LEU   A 1 80  ? 28.84597 -16.60538 21.64902 1.000 10.80920  ? 77  LEU   A O    1 
ATOM   1154 C CB   . LEU   A 1 80  ? 29.12409 -16.74569 24.90700 1.000 7.07870   ? 77  LEU   A CB   1 
ATOM   1155 C CG   . LEU   A 1 80  ? 29.47863 -17.63579 26.11293 1.000 16.31656  ? 77  LEU   A CG   1 
ATOM   1156 C CD1  . LEU   A 1 80  ? 28.45919 -17.43485 27.25242 1.000 40.61335  ? 77  LEU   A CD1  1 
ATOM   1157 C CD2  . LEU   A 1 80  ? 29.53792 -19.09713 25.73747 1.000 29.04081  ? 77  LEU   A CD2  1 
ATOM   1158 H H    . LEU   A 1 80  ? 31.50164 -16.21993 24.81070 1.000 5.58623   ? 77  LEU   A H    1 
ATOM   1159 H HA   . LEU   A 1 80  ? 29.94518 -17.89231 23.44358 1.000 11.14237  ? 77  LEU   A HA   1 
ATOM   1160 H HB2  . LEU   A 1 80  ? 29.19436 -15.82032 25.18922 1.000 8.58003   ? 77  LEU   A HB2  1 
ATOM   1161 H HB3  . LEU   A 1 80  ? 28.21080 -16.94516 24.64813 1.000 8.58003   ? 77  LEU   A HB3  1 
ATOM   1162 H HG   . LEU   A 1 80  ? 30.35970 -17.37415 26.42301 1.000 19.66546  ? 77  LEU   A HG   1 
ATOM   1163 H HD11 . LEU   A 1 80  ? 28.69445 -18.01581 27.99271 1.000 48.82160  ? 77  LEU   A HD11 1 
ATOM   1164 H HD12 . LEU   A 1 80  ? 28.48373 -16.50828 27.53835 1.000 48.82160  ? 77  LEU   A HD12 1 
ATOM   1165 H HD13 . LEU   A 1 80  ? 27.57310 -17.65701 26.92624 1.000 48.82160  ? 77  LEU   A HD13 1 
ATOM   1166 H HD21 . LEU   A 1 80  ? 30.29503 -19.24141 25.14852 1.000 34.93455  ? 77  LEU   A HD21 1 
ATOM   1167 H HD22 . LEU   A 1 80  ? 29.64051 -19.62645 26.54382 1.000 34.93455  ? 77  LEU   A HD22 1 
ATOM   1168 H HD23 . LEU   A 1 80  ? 28.71540 -19.34043 25.28450 1.000 34.93455  ? 77  LEU   A HD23 1 
ATOM   1169 N N    . GLY   A 1 81  ? 30.11099 -14.90010 22.38543 1.000 5.62545   ? 78  GLY   A N    1 
ATOM   1170 C CA   . GLY   A 1 81  ? 29.79632 -14.10711 21.20915 1.000 7.12280   ? 78  GLY   A CA   1 
ATOM   1171 C C    . GLY   A 1 81  ? 30.29917 -14.77181 19.94207 1.000 4.92218   ? 78  GLY   A C    1 
ATOM   1172 O O    . GLY   A 1 81  ? 29.56931 -14.89557 18.94377 1.000 6.19324   ? 78  GLY   A O    1 
ATOM   1173 H H    . GLY   A 1 81  ? 30.62152 -14.51568 22.96092 1.000 6.83612   ? 78  GLY   A H    1 
ATOM   1174 H HA2  . GLY   A 1 81  ? 28.83520 -13.99579 21.14010 1.000 8.63295   ? 78  GLY   A HA2  1 
ATOM   1175 H HA3  . GLY   A 1 81  ? 30.21070 -13.23346 21.28606 1.000 8.63295   ? 78  GLY   A HA3  1 
ATOM   1176 N N    . ALA   A 1 82  ? 31.53671 -15.27050 19.98742 1.000 4.56565   ? 79  ALA   A N    1 
ATOM   1177 C CA   . ALA   A 1 82  ? 32.10975 -15.88220 18.79000 1.000 12.44786  ? 79  ALA   A CA   1 
ATOM   1178 C C    . ALA   A 1 82  ? 31.37491 -17.16088 18.44671 1.000 9.15455   ? 79  ALA   A C    1 
ATOM   1179 O O    . ALA   A 1 82  ? 31.20881 -17.50189 17.26593 1.000 7.54993   ? 79  ALA   A O    1 
ATOM   1180 C CB   . ALA   A 1 82  ? 33.59101 -16.17232 18.98153 1.000 11.19932  ? 79  ALA   A CB   1 
ATOM   1181 H H    . ALA   A 1 82  ? 32.04930 -15.26711 20.67796 1.000 5.56436   ? 79  ALA   A H    1 
ATOM   1182 H HA   . ALA   A 1 82  ? 32.02667 -15.25503 18.05471 1.000 15.02301  ? 79  ALA   A HA   1 
ATOM   1183 H HB1  . ALA   A 1 82  ? 33.95860 -16.50274 18.14691 1.000 13.52477  ? 79  ALA   A HB1  1 
ATOM   1184 H HB2  . ALA   A 1 82  ? 34.04224 -15.35367 19.24059 1.000 13.52477  ? 79  ALA   A HB2  1 
ATOM   1185 H HB3  . ALA   A 1 82  ? 33.69455 -16.84119 19.67636 1.000 13.52477  ? 79  ALA   A HB3  1 
ATOM   1186 N N    A GLN   A 1 83  ? 30.92622 -17.88873 19.47068 0.525 8.57474   ? 80  GLN   A N    1 
ATOM   1187 N N    B GLN   A 1 83  ? 30.93282 -17.89427 19.46857 0.475 8.58040   ? 80  GLN   A N    1 
ATOM   1188 C CA   A GLN   A 1 83  ? 30.16469 -19.10741 19.22546 0.525 11.96877  ? 80  GLN   A CA   1 
ATOM   1189 C CA   B GLN   A 1 83  ? 30.16607 -19.10662 19.21193 0.475 11.96716  ? 80  GLN   A CA   1 
ATOM   1190 C C    A GLN   A 1 83  ? 28.83575 -18.79103 18.54665 0.525 12.30256  ? 80  GLN   A C    1 
ATOM   1191 C C    B GLN   A 1 83  ? 28.84637 -18.77510 18.52493 0.475 12.30236  ? 80  GLN   A C    1 
ATOM   1192 O O    A GLN   A 1 83  ? 28.40819 -19.50488 17.63189 0.525 12.65424  ? 80  GLN   A O    1 
ATOM   1193 O O    B GLN   A 1 83  ? 28.43557 -19.46234 17.58243 0.475 12.66044  ? 80  GLN   A O    1 
ATOM   1194 C CB   A GLN   A 1 83  ? 29.93284 -19.84894 20.54104 0.525 15.63442  ? 80  GLN   A CB   1 
ATOM   1195 C CB   B GLN   A 1 83  ? 29.91517 -19.85711 20.51793 0.475 15.65094  ? 80  GLN   A CB   1 
ATOM   1196 C CG   A GLN   A 1 83  ? 31.19877 -20.38459 21.19401 0.525 22.04540  ? 80  GLN   A CG   1 
ATOM   1197 C CG   B GLN   A 1 83  ? 29.13745 -21.16171 20.34192 0.475 20.40748  ? 80  GLN   A CG   1 
ATOM   1198 C CD   A GLN   A 1 83  ? 30.95371 -20.96596 22.58978 0.525 31.58990  ? 80  GLN   A CD   1 
ATOM   1199 C CD   B GLN   A 1 83  ? 28.71126 -21.77402 21.66574 0.475 28.82221  ? 80  GLN   A CD   1 
ATOM   1200 O OE1  A GLN   A 1 83  ? 29.82186 -21.28096 22.95909 0.525 38.07436  ? 80  GLN   A OE1  1 
ATOM   1201 O OE1  B GLN   A 1 83  ? 29.11190 -21.31442 22.73948 0.475 43.16834  ? 80  GLN   A OE1  1 
ATOM   1202 N NE2  A GLN   A 1 83  ? 32.01805 -21.09313 23.37160 0.525 22.07073  ? 80  GLN   A NE2  1 
ATOM   1203 N NE2  B GLN   A 1 83  ? 27.88976 -22.81458 21.59560 0.475 39.96525  ? 80  GLN   A NE2  1 
ATOM   1204 H H    A GLN   A 1 83  ? 31.04784 -17.70075 20.30103 0.525 10.37527  ? 80  GLN   A H    1 
ATOM   1205 H H    B GLN   A 1 83  ? 31.06110 -17.71460 20.29975 0.475 10.38207  ? 80  GLN   A H    1 
ATOM   1206 H HA   A GLN   A 1 83  ? 30.67386 -19.68833 18.63880 0.525 14.44811  ? 80  GLN   A HA   1 
ATOM   1207 H HA   B GLN   A 1 83  ? 30.67873 -19.68783 18.62861 0.475 14.44618  ? 80  GLN   A HA   1 
ATOM   1208 H HB2  A GLN   A 1 83  ? 29.51400 -19.24008 21.16934 0.525 18.84689  ? 80  GLN   A HB2  1 
ATOM   1209 H HB2  B GLN   A 1 83  ? 30.77009 -20.07461 20.92129 0.475 18.86672  ? 80  GLN   A HB2  1 
ATOM   1210 H HB3  A GLN   A 1 83  ? 29.34843 -20.60427 20.37124 0.525 18.84689  ? 80  GLN   A HB3  1 
ATOM   1211 H HB3  B GLN   A 1 83  ? 29.40377 -19.28584 21.11208 0.475 18.86672  ? 80  GLN   A HB3  1 
ATOM   1212 H HG2  A GLN   A 1 83  ? 31.56650 -21.08881 20.63746 0.525 26.54006  ? 80  GLN   A HG2  1 
ATOM   1213 H HG2  B GLN   A 1 83  ? 28.33803 -20.98558 19.82154 0.475 24.57456  ? 80  GLN   A HG2  1 
ATOM   1214 H HG3  A GLN   A 1 83  ? 31.83918 -19.66114 21.27999 0.525 26.54006  ? 80  GLN   A HG3  1 
ATOM   1215 H HG3  B GLN   A 1 83  ? 29.69857 -21.80463 19.88072 0.475 24.57456  ? 80  GLN   A HG3  1 
ATOM   1216 H HE21 A GLN   A 1 83  ? 32.79297 -20.85416 23.08523 0.525 26.57046  ? 80  GLN   A HE21 1 
ATOM   1217 H HE21 B GLN   A 1 83  ? 27.62878 -23.10552 20.82955 0.475 48.04389  ? 80  GLN   A HE21 1 
ATOM   1218 H HE22 A GLN   A 1 83  ? 31.93306 -21.41453 24.16474 0.525 26.57046  ? 80  GLN   A HE22 1 
ATOM   1219 H HE22 B GLN   A 1 83  ? 27.61859 -23.19768 22.31622 0.475 48.04389  ? 80  GLN   A HE22 1 
ATOM   1220 N N    . ASN   A 1 84  ? 28.16079 -17.72852 18.99232 1.000 9.33632   ? 81  ASN   A N    1 
ATOM   1221 C CA   . ASN   A 1 84  ? 26.94502 -17.28502 18.31916 1.000 9.76608   ? 81  ASN   A CA   1 
ATOM   1222 C C    . ASN   A 1 84  ? 27.23465 -16.85968 16.88857 1.000 10.44434  ? 81  ASN   A C    1 
ATOM   1223 O O    . ASN   A 1 84  ? 26.45373 -17.16780 15.98396 1.000 10.98372  ? 81  ASN   A O    1 
ATOM   1224 C CB   . ASN   A 1 84  ? 26.29622 -16.14943 19.11184 1.000 10.13586  ? 81  ASN   A CB   1 
ATOM   1225 C CG   . ASN   A 1 84  ? 25.59763 -16.65293 20.36085 1.000 19.04021  ? 81  ASN   A CG   1 
ATOM   1226 O OD1  . ASN   A 1 84  ? 24.90688 -17.66045 20.32639 1.000 21.15793  ? 81  ASN   A OD1  1 
ATOM   1227 N ND2  . ASN   A 1 84  ? 25.78535 -15.95983 21.46586 1.000 15.54844  ? 81  ASN   A ND2  1 
ATOM   1228 H H    A ASN   A 1 84  ? 28.38441 -17.25432 19.67403 0.525 11.28917  ? 81  ASN   A H    1 
ATOM   1229 H H    B ASN   A 1 84  ? 28.37628 -17.26744 19.68555 0.475 11.28917  ? 81  ASN   A H    1 
ATOM   1230 H HA   . ASN   A 1 84  ? 26.31305 -18.02011 18.28508 1.000 11.80489  ? 81  ASN   A HA   1 
ATOM   1231 H HB2  . ASN   A 1 84  ? 26.98077 -15.51737 19.38164 1.000 12.24862  ? 81  ASN   A HB2  1 
ATOM   1232 H HB3  . ASN   A 1 84  ? 25.63754 -15.70701 18.55389 1.000 12.24862  ? 81  ASN   A HB3  1 
ATOM   1233 H HD21 . ASN   A 1 84  ? 25.40903 -16.20798 22.19825 1.000 18.74372  ? 81  ASN   A HD21 1 
ATOM   1234 H HD22 . ASN   A 1 84  ? 26.28418 -15.25937 21.45458 1.000 18.74372  ? 81  ASN   A HD22 1 
ATOM   1235 N N    . LEU   A 1 85  ? 28.36672 -16.17757 16.65218 1.000 5.21608   ? 82  LEU   A N    1 
ATOM   1236 C CA   . LEU   A 1 85  ? 28.70862 -15.80357 15.28408 1.000 6.16372   ? 82  LEU   A CA   1 
ATOM   1237 C C    . LEU   A 1 85  ? 28.96599 -17.04491 14.43986 1.000 11.10292  ? 82  LEU   A C    1 
ATOM   1238 O O    . LEU   A 1 85  ? 28.60170 -17.08904 13.26108 1.000 9.48049   ? 82  LEU   A O    1 
ATOM   1239 C CB   . LEU   A 1 85  ? 29.93316 -14.89869 15.25309 1.000 7.68262   ? 82  LEU   A CB   1 
ATOM   1240 C CG   . LEU   A 1 85  ? 29.72086 -13.51388 15.87243 1.000 7.47742   ? 82  LEU   A CG   1 
ATOM   1241 C CD1  . LEU   A 1 85  ? 31.07123 -12.85659 15.93580 1.000 8.35458   ? 82  LEU   A CD1  1 
ATOM   1242 C CD2  . LEU   A 1 85  ? 28.76201 -12.67274 15.09450 1.000 13.10294  ? 82  LEU   A CD2  1 
ATOM   1243 H H    . LEU   A 1 85  ? 28.93201 -15.92984 17.25107 1.000 6.34488   ? 82  LEU   A H    1 
ATOM   1244 H HA   . LEU   A 1 85  ? 27.96488 -15.30604 14.90963 1.000 7.48204   ? 82  LEU   A HA   1 
ATOM   1245 H HB2  . LEU   A 1 85  ? 30.64863 -15.33245 15.74386 1.000 9.30473   ? 82  LEU   A HB2  1 
ATOM   1246 H HB3  . LEU   A 1 85  ? 30.19631 -14.76880 14.32854 1.000 9.30473   ? 82  LEU   A HB3  1 
ATOM   1247 H HG   . LEU   A 1 85  ? 29.32653 -13.60041 16.75443 1.000 9.05848   ? 82  LEU   A HG   1 
ATOM   1248 H HD11 . LEU   A 1 85  ? 30.96169 -11.93721 16.22503 1.000 10.11108  ? 82  LEU   A HD11 1 
ATOM   1249 H HD12 . LEU   A 1 85  ? 31.62751 -13.33815 16.56790 1.000 10.11108  ? 82  LEU   A HD12 1 
ATOM   1250 H HD13 . LEU   A 1 85  ? 31.47559 -12.88012 15.05441 1.000 10.11108  ? 82  LEU   A HD13 1 
ATOM   1251 H HD21 . LEU   A 1 85  ? 28.66834 -11.81276 15.53331 1.000 15.80911  ? 82  LEU   A HD21 1 
ATOM   1252 H HD22 . LEU   A 1 85  ? 29.10657 -12.54990 14.19612 1.000 15.80911  ? 82  LEU   A HD22 1 
ATOM   1253 H HD23 . LEU   A 1 85  ? 27.90307 -13.12217 15.06076 1.000 15.80911  ? 82  LEU   A HD23 1 
ATOM   1254 N N    . SER   A 1 86  ? 29.57183 -18.07055 15.04114 1.000 6.72503   ? 83  SER   A N    1 
ATOM   1255 C CA   . SER   A 1 86  ? 30.00896 -19.24792 14.29443 1.000 9.49825   ? 83  SER   A CA   1 
ATOM   1256 C C    . SER   A 1 86  ? 28.82272 -20.10049 13.89268 1.000 17.21259  ? 83  SER   A C    1 
ATOM   1257 O O    . SER   A 1 86  ? 28.90280 -20.86596 12.93299 1.000 13.43675  ? 83  SER   A O    1 
ATOM   1258 C CB   . SER   A 1 86  ? 30.97452 -20.09954 15.12926 1.000 8.70541   ? 83  SER   A CB   1 
ATOM   1259 O OG   . SER   A 1 86  ? 32.18171 -19.41487 15.39463 1.000 15.37031  ? 83  SER   A OG   1 
ATOM   1260 H H    . SER   A 1 86  ? 29.74209 -18.10942 15.88323 1.000 8.15562   ? 83  SER   A H    1 
ATOM   1261 H HA   . SER   A 1 86  ? 30.48098 -18.94734 13.50213 1.000 11.48348  ? 83  SER   A HA   1 
ATOM   1262 H HB2  . SER   A 1 86  ? 30.54813 -20.31857 15.97254 1.000 10.53207  ? 83  SER   A HB2  1 
ATOM   1263 H HB3  . SER   A 1 86  ? 31.17761 -20.91174 14.63938 1.000 10.53207  ? 83  SER   A HB3  1 
ATOM   1264 H HG   . SER   A 1 86  ? 32.02043 -18.68914 15.78566 1.000 18.52995  ? 83  SER   A HG   1 
ATOM   1265 N N    . GLU   A 1 87  ? 27.72732 -20.00126 14.63079 1.000 8.43543   ? 84  GLU   A N    1 
ATOM   1266 C CA   . GLU   A 1 87  ? 26.54064 -20.81352 14.38065 1.000 13.02536  ? 84  GLU   A CA   1 
ATOM   1267 C C    . GLU   A 1 87  ? 25.51690 -20.15153 13.46327 1.000 15.62332  ? 84  GLU   A C    1 
ATOM   1268 O O    . GLU   A 1 87  ? 24.53316 -20.79618 13.08370 1.000 24.03713  ? 84  GLU   A O    1 
ATOM   1269 C CB   . GLU   A 1 87  ? 25.84742 -21.16126 15.70499 1.000 24.03683  ? 84  GLU   A CB   1 
ATOM   1270 C CG   . GLU   A 1 87  ? 26.63165 -22.10329 16.60083 1.000 26.57944  ? 84  GLU   A CG   1 
ATOM   1271 C CD   . GLU   A 1 87  ? 26.00407 -22.24510 17.99333 1.000 51.37654  ? 84  GLU   A CD   1 
ATOM   1272 O OE1  . GLU   A 1 87  ? 24.89899 -21.68886 18.23040 1.000 46.64879  ? 84  GLU   A OE1  1 
ATOM   1273 O OE2  . GLU   A 1 87  ? 26.63209 -22.89917 18.85644 1.000 69.58702  ? 84  GLU   A OE2  1 
ATOM   1274 H H    . GLU   A 1 87  ? 27.64223 -19.46176 15.29509 1.000 10.20810  ? 84  GLU   A H    1 
ATOM   1275 H HA   . GLU   A 1 87  ? 26.83363 -21.63410 13.95438 1.000 15.71601  ? 84  GLU   A HA   1 
ATOM   1276 H HB2  . GLU   A 1 87  ? 25.70031 -20.34071 16.20093 1.000 28.92978  ? 84  GLU   A HB2  1 
ATOM   1277 H HB3  . GLU   A 1 87  ? 24.99811 -21.58571 15.50646 1.000 28.92978  ? 84  GLU   A HB3  1 
ATOM   1278 H HG2  . GLU   A 1 87  ? 26.65801 -22.98221 16.19131 1.000 31.98092  ? 84  GLU   A HG2  1 
ATOM   1279 H HG3  . GLU   A 1 87  ? 27.53266 -21.76094 16.70987 1.000 31.98092  ? 84  GLU   A HG3  1 
ATOM   1280 N N    . SER   A 1 88  ? 25.70887 -18.89261 13.10268 1.000 8.99326   ? 85  SER   A N    1 
ATOM   1281 C CA   . SER   A 1 88  ? 24.69198 -18.14601 12.38756 1.000 15.75251  ? 85  SER   A CA   1 
ATOM   1282 C C    . SER   A 1 88  ? 24.88710 -18.27626 10.88491 1.000 14.69924  ? 85  SER   A C    1 
ATOM   1283 O O    . SER   A 1 88  ? 25.95181 -17.94883 10.35367 1.000 11.27523  ? 85  SER   A O    1 
ATOM   1284 C CB   . SER   A 1 88  ? 24.73644 -16.68004 12.79222 1.000 14.11044  ? 85  SER   A CB   1 
ATOM   1285 O OG   . SER   A 1 88  ? 24.12270 -15.89094 11.81818 1.000 15.62642  ? 85  SER   A OG   1 
ATOM   1286 H H    . SER   A 1 88  ? 26.42633 -18.44626 13.26272 1.000 10.87750  ? 85  SER   A H    1 
ATOM   1287 H HA   . SER   A 1 88  ? 23.81973 -18.50959 12.60639 1.000 18.98860  ? 85  SER   A HA   1 
ATOM   1288 H HB2  . SER   A 1 88  ? 24.26774 -16.56808 13.63405 1.000 17.01812  ? 85  SER   A HB2  1 
ATOM   1289 H HB3  . SER   A 1 88  ? 25.66150 -16.40451 12.88835 1.000 17.01812  ? 85  SER   A HB3  1 
ATOM   1290 H HG   . SER   A 1 88  ? 24.17471 -15.07995 12.03074 1.000 18.83729  ? 85  SER   A HG   1 
ATOM   1291 N N    . ALA   A 1 89  ? 23.83429 -18.70979 10.19079 1.000 15.83302  ? 86  ALA   A N    1 
ATOM   1292 C CA   . ALA   A 1 89  ? 23.91730 -18.81203 8.72829  1.000 18.56532  ? 86  ALA   A CA   1 
ATOM   1293 C C    . ALA   A 1 89  ? 23.98903 -17.43683 8.06308  1.000 14.53630  ? 86  ALA   A C    1 
ATOM   1294 O O    . ALA   A 1 89  ? 24.60459 -17.27531 6.98770  1.000 13.51108  ? 86  ALA   A O    1 
ATOM   1295 C CB   . ALA   A 1 89  ? 22.71766 -19.59443 8.18475  1.000 25.65150  ? 86  ALA   A CB   1 
ATOM   1296 H H    . ALA   A 1 89  ? 23.07977 -18.94529 10.52967 1.000 19.08521  ? 86  ALA   A H    1 
ATOM   1297 H HA   . ALA   A 1 89  ? 24.72555 -19.29798 8.50140  1.000 22.36397  ? 86  ALA   A HA   1 
ATOM   1298 H HB1  . ALA   A 1 89  ? 22.80282 -19.67437 7.22181  1.000 30.86738  ? 86  ALA   A HB1  1 
ATOM   1299 H HB2  . ALA   A 1 89  ? 22.70547 -20.47562 8.59003  1.000 30.86738  ? 86  ALA   A HB2  1 
ATOM   1300 H HB3  . ALA   A 1 89  ? 21.90276 -19.11717 8.40627  1.000 30.86738  ? 86  ALA   A HB3  1 
ATOM   1301 N N    . ALA   A 1 90  ? 23.37229 -16.43220 8.68800  1.000 11.25806  ? 87  ALA   A N    1 
ATOM   1302 C CA   . ALA   A 1 90  ? 23.45747 -15.08045 8.15023  1.000 14.06141  ? 87  ALA   A CA   1 
ATOM   1303 C C    . ALA   A 1 90  ? 24.89265 -14.56388 8.18056  1.000 16.28227  ? 87  ALA   A C    1 
ATOM   1304 O O    . ALA   A 1 90  ? 25.32275 -13.84293 7.27020  1.000 15.29628  ? 87  ALA   A O    1 
ATOM   1305 C CB   . ALA   A 1 90  ? 22.53656 -14.14761 8.93807  1.000 21.46434  ? 87  ALA   A CB   1 
ATOM   1306 H H    . ALA   A 1 90  ? 22.90904 -16.50718 9.40868  1.000 13.59526  ? 87  ALA   A H    1 
ATOM   1307 H HA   . ALA   A 1 90  ? 23.16083 -15.09067 7.22676  1.000 16.95927  ? 87  ALA   A HA   1 
ATOM   1308 H HB1  . ALA   A 1 90  ? 22.62900 -13.24622 8.59187  1.000 25.84280  ? 87  ALA   A HB1  1 
ATOM   1309 H HB2  . ALA   A 1 90  ? 21.62009 -14.44866 8.83631  1.000 25.84280  ? 87  ALA   A HB2  1 
ATOM   1310 H HB3  . ALA   A 1 90  ? 22.79010 -14.17007 9.87408  1.000 25.84280  ? 87  ALA   A HB3  1 
ATOM   1311 N N    . VAL   A 1 91  ? 25.65286 -14.90772 9.22402  1.000 15.08560  ? 88  VAL   A N    1 
ATOM   1312 C CA   . VAL   A 1 91  ? 27.05389 -14.50837 9.23217  1.000 9.59308   ? 88  VAL   A CA   1 
ATOM   1313 C C    . VAL   A 1 91  ? 27.79955 -15.18956 8.09456  1.000 8.68745   ? 88  VAL   A C    1 
ATOM   1314 O O    . VAL   A 1 91  ? 28.61501 -14.55780 7.41345  1.000 12.85313  ? 88  VAL   A O    1 
ATOM   1315 C CB   . VAL   A 1 91  ? 27.68968 -14.79777 10.60449 1.000 12.94105  ? 88  VAL   A CB   1 
ATOM   1316 C CG1  . VAL   A 1 91  ? 29.14718 -14.44844 10.58013 1.000 10.70277  ? 88  VAL   A CG1  1 
ATOM   1317 C CG2  . VAL   A 1 91  ? 26.98452 -13.96725 11.67894 1.000 16.72279  ? 88  VAL   A CG2  1 
ATOM   1318 H H    . VAL   A 1 91  ? 25.38906 -15.35392 9.91025  1.000 18.18831  ? 88  VAL   A H    1 
ATOM   1319 H HA   . VAL   A 1 91  ? 27.10688 -13.55059 9.08815  1.000 11.59729  ? 88  VAL   A HA   1 
ATOM   1320 H HB   . VAL   A 1 91  ? 27.59606 -15.74088 10.81104 1.000 15.61484  ? 88  VAL   A HB   1 
ATOM   1321 H HG11 . VAL   A 1 91  ? 29.48903 -14.45634 11.48786 1.000 12.92891  ? 88  VAL   A HG11 1 
ATOM   1322 H HG12 . VAL   A 1 91  ? 29.61994 -15.10327 10.04292 1.000 12.92891  ? 88  VAL   A HG12 1 
ATOM   1323 H HG13 . VAL   A 1 91  ? 29.25376 -13.56492 10.19421 1.000 12.92891  ? 88  VAL   A HG13 1 
ATOM   1324 H HG21 . VAL   A 1 91  ? 27.39955 -14.14395 12.53767 1.000 20.15294  ? 88  VAL   A HG21 1 
ATOM   1325 H HG22 . VAL   A 1 91  ? 27.06979 -13.02669 11.45763 1.000 20.15294  ? 88  VAL   A HG22 1 
ATOM   1326 H HG23 . VAL   A 1 91  ? 26.04760 -14.21689 11.70675 1.000 20.15294  ? 88  VAL   A HG23 1 
ATOM   1327 N N    . LYS   A 1 92  ? 27.54154 -16.48949 7.88451  1.000 11.85219  ? 89  LYS   A N    1 
ATOM   1328 C CA   . LYS   A 1 92  ? 28.20562 -17.22907 6.81571  1.000 15.13702  ? 89  LYS   A CA   1 
ATOM   1329 C C    . LYS   A 1 92  ? 28.00415 -16.50731 5.49572  1.000 13.66165  ? 89  LYS   A C    1 
ATOM   1330 O O    . LYS   A 1 92  ? 28.95815 -16.23539 4.76353  1.000 12.79366  ? 89  LYS   A O    1 
ATOM   1331 C CB   . LYS   A 1 92  ? 27.65983 -18.66278 6.74055  1.000 18.25399  ? 89  LYS   A CB   1 
ATOM   1332 C CG   . LYS   A 1 92  ? 28.39915 -19.58009 5.75529  1.000 23.67844  ? 89  LYS   A CG   1 
ATOM   1333 C CD   . LYS   A 1 92  ? 27.78402 -20.99131 5.67965  1.000 31.77977  ? 89  LYS   A CD   1 
ATOM   1334 C CE   . LYS   A 1 92  ? 27.57836 -21.64318 7.06910  1.000 43.62594  ? 89  LYS   A CE   1 
ATOM   1335 N NZ   . LYS   A 1 92  ? 28.82772 -21.94825 7.85818  1.000 29.65326  ? 89  LYS   A NZ   1 
ATOM   1336 H H    . LYS   A 1 92  ? 26.98871 -16.95879 8.34682  1.000 14.30822  ? 89  LYS   A H    1 
ATOM   1337 H HA   . LYS   A 1 92  ? 29.15524 -17.29200 7.00324  1.000 18.25001  ? 89  LYS   A HA   1 
ATOM   1338 H HB2  . LYS   A 1 92  ? 27.72733 -19.06472 7.62077  1.000 21.99038  ? 89  LYS   A HB2  1 
ATOM   1339 H HB3  . LYS   A 1 92  ? 26.73100 -18.62477 6.46353  1.000 21.99038  ? 89  LYS   A HB3  1 
ATOM   1340 H HG2  . LYS   A 1 92  ? 28.36100 -19.18863 4.86861  1.000 28.49971  ? 89  LYS   A HG2  1 
ATOM   1341 H HG3  . LYS   A 1 92  ? 29.32244 -19.67042 6.03863  1.000 28.49971  ? 89  LYS   A HG3  1 
ATOM   1342 H HD2  . LYS   A 1 92  ? 26.91791 -20.93427 5.24665  1.000 38.22131  ? 89  LYS   A HD2  1 
ATOM   1343 H HD3  . LYS   A 1 92  ? 28.37440 -21.56483 5.16640  1.000 38.22131  ? 89  LYS   A HD3  1 
ATOM   1344 H HE2  . LYS   A 1 92  ? 27.04133 -21.04194 7.60856  1.000 52.43671  ? 89  LYS   A HE2  1 
ATOM   1345 H HE3  . LYS   A 1 92  ? 27.11005 -22.48317 6.94256  1.000 52.43671  ? 89  LYS   A HE3  1 
ATOM   1346 H HZ1  . LYS   A 1 92  ? 28.68023 -21.81423 8.72558  1.000 35.66950  ? 89  LYS   A HZ1  1 
ATOM   1347 H HZ2  . LYS   A 1 92  ? 29.49212 -21.41877 7.59299  1.000 35.66950  ? 89  LYS   A HZ2  1 
ATOM   1348 H HZ3  . LYS   A 1 92  ? 29.06696 -22.79638 7.73355  1.000 35.66950  ? 89  LYS   A HZ3  1 
ATOM   1349 N N    . GLU   A 1 93  ? 26.75999 -16.14019 5.20254  1.000 10.51255  ? 90  GLU   A N    1 
ATOM   1350 C CA   . GLU   A 1 93  ? 26.45874 -15.50419 3.92212  1.000 18.43194  ? 90  GLU   A CA   1 
ATOM   1351 C C    . GLU   A 1 93  ? 27.15167 -14.15602 3.80955  1.000 16.80152  ? 90  GLU   A C    1 
ATOM   1352 O O    . GLU   A 1 93  ? 27.74512 -13.82978 2.77509  1.000 10.57452  ? 90  GLU   A O    1 
ATOM   1353 C CB   . GLU   A 1 93  ? 24.94333 -15.34332 3.78730  1.000 18.51657  ? 90  GLU   A CB   1 
ATOM   1354 C CG   . GLU   A 1 93  ? 24.43294 -14.61192 2.56066  1.000 61.92386  ? 90  GLU   A CG   1 
ATOM   1355 C CD   . GLU   A 1 93  ? 22.90054 -14.45048 2.56904  1.000 65.54000  ? 90  GLU   A CD   1 
ATOM   1356 O OE1  . GLU   A 1 93  ? 22.23318 -15.10082 3.40999  1.000 54.66016  ? 90  GLU   A OE1  1 
ATOM   1357 O OE2  . GLU   A 1 93  ? 22.36942 -13.66999 1.74035  1.000 64.75785  ? 90  GLU   A OE2  1 
ATOM   1358 H H    . GLU   A 1 93  ? 26.08045 -16.24574 5.71896  1.000 12.70065  ? 90  GLU   A H    1 
ATOM   1359 H HA   . GLU   A 1 93  ? 26.77617 -16.06435 3.19662  1.000 22.20392  ? 90  GLU   A HA   1 
ATOM   1360 H HB2  . GLU   A 1 93  ? 24.54903 -16.22942 3.77142  1.000 22.30547  ? 90  GLU   A HB2  1 
ATOM   1361 H HB3  . GLU   A 1 93  ? 24.62497 -14.85234 4.56092  1.000 22.30547  ? 90  GLU   A HB3  1 
ATOM   1362 H HG2  . GLU   A 1 93  ? 24.82919 -13.72705 2.53081  1.000 74.39422  ? 90  GLU   A HG2  1 
ATOM   1363 H HG3  . GLU   A 1 93  ? 24.67904 -15.11257 1.76714  1.000 74.39422  ? 90  GLU   A HG3  1 
ATOM   1364 N N    . ILE   A 1 94  ? 27.12167 -13.37071 4.88446  1.000 14.73860  ? 91  ILE   A N    1 
ATOM   1365 C CA   . ILE   A 1 94  ? 27.77720 -12.06239 4.86794  1.000 11.22084  ? 91  ILE   A CA   1 
ATOM   1366 C C    . ILE   A 1 94  ? 29.27786 -12.21823 4.64983  1.000 13.09338  ? 91  ILE   A C    1 
ATOM   1367 O O    . ILE   A 1 94  ? 29.90447 -11.49678 3.86178  1.000 8.79429   ? 91  ILE   A O    1 
ATOM   1368 C CB   . ILE   A 1 94  ? 27.49275 -11.30644 6.17959  1.000 16.74875  ? 91  ILE   A CB   1 
ATOM   1369 C CG1  . ILE   A 1 94  ? 26.05844 -10.79122 6.18685  1.000 27.93302  ? 91  ILE   A CG1  1 
ATOM   1370 C CG2  . ILE   A 1 94  ? 28.47840 -10.18250 6.35356  1.000 19.25739  ? 91  ILE   A CG2  1 
ATOM   1371 C CD1  . ILE   A 1 94  ? 25.56473 -10.32880 7.55385  1.000 33.64675  ? 91  ILE   A CD1  1 
ATOM   1372 H H    . ILE   A 1 94  ? 26.73432 -13.56749 5.62665  1.000 17.77191  ? 91  ILE   A H    1 
ATOM   1373 H HA   . ILE   A 1 94  ? 27.41352 -11.55081 4.12840  1.000 13.55060  ? 91  ILE   A HA   1 
ATOM   1374 H HB   . ILE   A 1 94  ? 27.59639 -11.91704 6.92613  1.000 20.18409  ? 91  ILE   A HB   1 
ATOM   1375 H HG12 . ILE   A 1 94  ? 25.99757 -10.03571 5.58154  1.000 33.60521  ? 91  ILE   A HG12 1 
ATOM   1376 H HG13 . ILE   A 1 94  ? 25.47182 -11.50368 5.88823  1.000 33.60521  ? 91  ILE   A HG13 1 
ATOM   1377 H HG21 . ILE   A 1 94  ? 28.12416 -9.54850  6.99657  1.000 23.19445  ? 91  ILE   A HG21 1 
ATOM   1378 H HG22 . ILE   A 1 94  ? 29.31816 -10.54589 6.67550  1.000 23.19445  ? 91  ILE   A HG22 1 
ATOM   1379 H HG23 . ILE   A 1 94  ? 28.61336 -9.74557  5.49811  1.000 23.19445  ? 91  ILE   A HG23 1 
ATOM   1380 H HD11 . ILE   A 1 94  ? 24.61256 -10.15102 7.50218  1.000 40.46168  ? 91  ILE   A HD11 1 
ATOM   1381 H HD12 . ILE   A 1 94  ? 25.73592 -11.02762 8.20442  1.000 40.46168  ? 91  ILE   A HD12 1 
ATOM   1382 H HD13 . ILE   A 1 94  ? 26.03903 -9.52052  7.80408  1.000 40.46168  ? 91  ILE   A HD13 1 
ATOM   1383 N N    . LEU   A 1 95  ? 29.88875 -13.14634 5.37191  1.000 8.39282   ? 92  LEU   A N    1 
ATOM   1384 C CA   . LEU   A 1 95  ? 31.33405 -13.31186 5.23175  1.000 8.04039   ? 92  LEU   A CA   1 
ATOM   1385 C C    . LEU   A 1 95  ? 31.71355 -13.84828 3.84578  1.000 13.32246  ? 92  LEU   A C    1 
ATOM   1386 O O    . LEU   A 1 95  ? 32.67724 -13.36170 3.22295  1.000 9.85596   ? 92  LEU   A O    1 
ATOM   1387 C CB   . LEU   A 1 95  ? 31.85950 -14.23118 6.33778  1.000 13.72155  ? 92  LEU   A CB   1 
ATOM   1388 C CG   . LEU   A 1 95  ? 31.71096 -13.70325 7.78017  1.000 13.04381  ? 92  LEU   A CG   1 
ATOM   1389 C CD1  . LEU   A 1 95  ? 32.13662 -14.76493 8.79930  1.000 13.29151  ? 92  LEU   A CD1  1 
ATOM   1390 C CD2  . LEU   A 1 95  ? 32.52168 -12.43712 7.97706  1.000 16.40055  ? 92  LEU   A CD2  1 
ATOM   1391 H H    A LEU   A 1 95  ? 29.50697 -13.67636 5.93131  0.650 10.15697  ? 92  LEU   A H    1 
ATOM   1392 H H    B LEU   A 1 95  ? 29.50717 -13.67646 5.93136  0.350 10.15697  ? 92  LEU   A H    1 
ATOM   1393 H HA   . LEU   A 1 95  ? 31.75721 -12.44473 5.33131  1.000 9.73405   ? 92  LEU   A HA   1 
ATOM   1394 H HB2  . LEU   A 1 95  ? 31.37717 -15.07127 6.28786  1.000 16.55145  ? 92  LEU   A HB2  1 
ATOM   1395 H HB3  . LEU   A 1 95  ? 32.80508 -14.38179 6.18256  1.000 16.55145  ? 92  LEU   A HB3  1 
ATOM   1396 H HG   . LEU   A 1 95  ? 30.77625 -13.49408 7.93342  1.000 15.73816  ? 92  LEU   A HG   1 
ATOM   1397 H HD11 . LEU   A 1 95  ? 31.99071 -14.42016 9.69414  1.000 16.03539  ? 92  LEU   A HD11 1 
ATOM   1398 H HD12 . LEU   A 1 95  ? 31.60552 -15.56498 8.66239  1.000 16.03539  ? 92  LEU   A HD12 1 
ATOM   1399 H HD13 . LEU   A 1 95  ? 33.07688 -14.96621 8.67160  1.000 16.03539  ? 92  LEU   A HD13 1 
ATOM   1400 H HD21 . LEU   A 1 95  ? 32.56025 -12.23089 8.92409  1.000 19.76624  ? 92  LEU   A HD21 1 
ATOM   1401 H HD22 . LEU   A 1 95  ? 33.41733 -12.57887 7.63265  1.000 19.76624  ? 92  LEU   A HD22 1 
ATOM   1402 H HD23 . LEU   A 1 95  ? 32.09401 -11.71050 7.49745  1.000 19.76624  ? 92  LEU   A HD23 1 
ATOM   1403 N N    A LYS   A 1 96  ? 30.99240 -14.86737 3.35670  0.599 13.55412  ? 93  LYS   A N    1 
ATOM   1404 N N    B LYS   A 1 96  ? 31.00475 -14.87837 3.36302  0.401 13.55246  ? 93  LYS   A N    1 
ATOM   1405 C CA   A LYS   A 1 96  ? 31.30893 -15.42132 2.03792  0.599 13.47243  ? 93  LYS   A CA   1 
ATOM   1406 C CA   B LYS   A 1 96  ? 31.32058 -15.41611 2.03810  0.401 13.51566  ? 93  LYS   A CA   1 
ATOM   1407 C C    A LYS   A 1 96  ? 31.19095 -14.34730 0.96198  0.599 15.23849  ? 93  LYS   A C    1 
ATOM   1408 C C    B LYS   A 1 96  ? 31.21530 -14.32441 0.97832  0.401 15.24890  ? 93  LYS   A C    1 
ATOM   1409 O O    A LYS   A 1 96  ? 32.02364 -14.26880 0.05091  0.599 16.35161  ? 93  LYS   A O    1 
ATOM   1410 O O    B LYS   A 1 96  ? 32.06775 -14.22028 0.08656  0.401 16.37079  ? 93  LYS   A O    1 
ATOM   1411 C CB   A LYS   A 1 96  ? 30.40006 -16.61784 1.72164  0.599 16.83226  ? 93  LYS   A CB   1 
ATOM   1412 C CB   B LYS   A 1 96  ? 30.39798 -16.59045 1.68874  0.401 16.82485  ? 93  LYS   A CB   1 
ATOM   1413 C CG   A LYS   A 1 96  ? 30.70354 -17.85369 2.58500  0.599 23.35347  ? 93  LYS   A CG   1 
ATOM   1414 C CG   B LYS   A 1 96  ? 30.90609 -17.96394 2.15424  0.401 22.83446  ? 93  LYS   A CG   1 
ATOM   1415 C CD   A LYS   A 1 96  ? 29.98952 -19.10864 2.10494  0.599 23.62710  ? 93  LYS   A CD   1 
ATOM   1416 C CD   B LYS   A 1 96  ? 32.18013 -18.37996 1.42339  0.401 17.51758  ? 93  LYS   A CD   1 
ATOM   1417 C CE   A LYS   A 1 96  ? 30.38269 -20.33641 2.94018  0.599 30.63973  ? 93  LYS   A CE   1 
ATOM   1418 C CE   B LYS   A 1 96  ? 32.76449 -19.67634 1.98050  0.401 15.63109  ? 93  LYS   A CE   1 
ATOM   1419 N NZ   A LYS   A 1 96  ? 31.82162 -20.73394 2.75578  0.599 30.42265  ? 93  LYS   A NZ   1 
ATOM   1420 N NZ   B LYS   A 1 96  ? 34.20994 -19.84086 1.60903  0.401 15.32733  ? 93  LYS   A NZ   1 
ATOM   1421 H H    A LYS   A 1 96  ? 30.33266 -15.24478 3.75908  0.599 16.35053  ? 93  LYS   A H    1 
ATOM   1422 H H    B LYS   A 1 96  ? 30.35696 -15.27014 3.77105  0.401 16.34853  ? 93  LYS   A H    1 
ATOM   1423 H HA   A LYS   A 1 96  ? 32.22183 -15.74917 2.04427  0.599 16.25250  ? 93  LYS   A HA   1 
ATOM   1424 H HA   B LYS   A 1 96  ? 32.22885 -15.75638 2.05078  0.401 16.30437  ? 93  LYS   A HA   1 
ATOM   1425 H HB2  A LYS   A 1 96  ? 29.47787 -16.36215 1.88002  0.599 20.28430  ? 93  LYS   A HB2  1 
ATOM   1426 H HB2  B LYS   A 1 96  ? 29.53577 -16.44040 2.10705  0.401 20.27541  ? 93  LYS   A HB2  1 
ATOM   1427 H HB3  A LYS   A 1 96  ? 30.52041 -16.86639 0.79178  0.599 20.28430  ? 93  LYS   A HB3  1 
ATOM   1428 H HB3  B LYS   A 1 96  ? 30.29709 -16.62727 0.72470  0.401 20.27541  ? 93  LYS   A HB3  1 
ATOM   1429 H HG2  A LYS   A 1 96  ? 31.65769 -18.02691 2.56274  0.599 28.10975  ? 93  LYS   A HG2  1 
ATOM   1430 H HG2  B LYS   A 1 96  ? 31.09996 -17.92770 3.10398  0.401 27.48693  ? 93  LYS   A HG2  1 
ATOM   1431 H HG3  A LYS   A 1 96  ? 30.41920 -17.67918 3.49582  0.599 28.10975  ? 93  LYS   A HG3  1 
ATOM   1432 H HG3  B LYS   A 1 96  ? 30.22507 -18.63232 1.97993  0.401 27.48693  ? 93  LYS   A HG3  1 
ATOM   1433 H HD2  A LYS   A 1 96  ? 29.03092 -18.98203 2.18215  0.599 28.43811  ? 93  LYS   A HD2  1 
ATOM   1434 H HD2  B LYS   A 1 96  ? 31.97884 -18.51792 0.48459  0.401 21.10669  ? 93  LYS   A HD2  1 
ATOM   1435 H HD3  A LYS   A 1 96  ? 30.22813 -19.28004 1.18051  0.599 28.43811  ? 93  LYS   A HD3  1 
ATOM   1436 H HD3  B LYS   A 1 96  ? 32.84629 -17.68164 1.52072  0.401 21.10669  ? 93  LYS   A HD3  1 
ATOM   1437 H HE2  A LYS   A 1 96  ? 30.24574 -20.13631 3.87939  0.599 36.85326  ? 93  LYS   A HE2  1 
ATOM   1438 H HE2  B LYS   A 1 96  ? 32.69861 -19.66719 2.94822  0.401 18.84289  ? 93  LYS   A HE2  1 
ATOM   1439 H HE3  A LYS   A 1 96  ? 29.82875 -21.08789 2.67688  0.599 36.85326  ? 93  LYS   A HE3  1 
ATOM   1440 H HE3  B LYS   A 1 96  ? 32.27081 -20.43018 1.62148  0.401 18.84289  ? 93  LYS   A HE3  1 
ATOM   1441 H HZ1  A LYS   A 1 96  ? 31.97372 -20.93978 1.90338  0.599 36.59277  ? 93  LYS   A HZ1  1 
ATOM   1442 H HZ1  B LYS   A 1 96  ? 34.68773 -19.16645 1.93915  0.401 18.47837  ? 93  LYS   A HZ1  1 
ATOM   1443 H HZ2  A LYS   A 1 96  ? 32.00913 -21.44172 3.26173  0.599 36.59277  ? 93  LYS   A HZ2  1 
ATOM   1444 H HZ2  B LYS   A 1 96  ? 34.52378 -20.60570 1.93862  0.401 18.47837  ? 93  LYS   A HZ2  1 
ATOM   1445 H HZ3  A LYS   A 1 96  ? 32.35561 -20.06165 2.99029  0.599 36.59277  ? 93  LYS   A HZ3  1 
ATOM   1446 H HZ3  B LYS   A 1 96  ? 34.29743 -19.85050 0.72339  0.401 18.47837  ? 93  LYS   A HZ3  1 
ATOM   1447 N N    . GLU   A 1 97  ? 30.19180 -13.47346 1.07914  1.000 12.80060  ? 94  GLU   A N    1 
ATOM   1448 C CA   . GLU   A 1 97  ? 30.03700 -12.40169 0.09690  1.000 14.92934  ? 94  GLU   A CA   1 
ATOM   1449 C C    . GLU   A 1 97  ? 31.17403 -11.39169 0.19453  1.000 23.70272  ? 94  GLU   A C    1 
ATOM   1450 O O    . GLU   A 1 97  ? 31.66649 -10.88725 -0.82756 1.000 12.41084  ? 94  GLU   A O    1 
ATOM   1451 C CB   . GLU   A 1 97  ? 28.68890 -11.70666 0.28216  1.000 16.34858  ? 94  GLU   A CB   1 
ATOM   1452 C CG   . GLU   A 1 97  ? 28.55413 -10.40944 -0.49167 1.000 30.30086  ? 94  GLU   A CG   1 
ATOM   1453 C CD   . GLU   A 1 97  ? 27.31031 -9.61711  -0.07985 1.000 68.25072  ? 94  GLU   A CD   1 
ATOM   1454 O OE1  . GLU   A 1 97  ? 26.38933 -10.21788 0.52565  1.000 64.35839  ? 94  GLU   A OE1  1 
ATOM   1455 O OE2  . GLU   A 1 97  ? 27.26111 -8.39736  -0.35748 1.000 69.62913  ? 94  GLU   A OE2  1 
ATOM   1456 H H    A GLU   A 1 97  ? 29.60169 -13.47814 1.70472  0.599 15.44631  ? 94  GLU   A H    1 
ATOM   1457 H H    B GLU   A 1 97  ? 29.58838 -13.49456 1.69155  0.401 15.44631  ? 94  GLU   A H    1 
ATOM   1458 H HA   . GLU   A 1 97  ? 30.05488 -12.79152 -0.79113 1.000 18.00079  ? 94  GLU   A HA   1 
ATOM   1459 H HB2  . GLU   A 1 97  ? 27.98673 -12.30442 -0.01873 1.000 19.70388  ? 94  GLU   A HB2  1 
ATOM   1460 H HB3  . GLU   A 1 97  ? 28.57059 -11.50297 1.22312  1.000 19.70388  ? 94  GLU   A HB3  1 
ATOM   1461 H HG2  . GLU   A 1 97  ? 29.33364 -9.85680  -0.32477 1.000 36.44662  ? 94  GLU   A HG2  1 
ATOM   1462 H HG3  . GLU   A 1 97  ? 28.48563 -10.60921 -1.43840 1.000 36.44662  ? 94  GLU   A HG3  1 
ATOM   1463 N N    . GLN   A 1 98  ? 31.58323 -11.06209 1.41692  1.000 13.20509  ? 95  GLN   A N    1 
ATOM   1464 C CA   . GLN   A 1 98  ? 32.67774 -10.11508 1.58750  1.000 11.63074  ? 95  GLN   A CA   1 
ATOM   1465 C C    . GLN   A 1 98  ? 33.97776 -10.68101 1.02171  1.000 8.32743   ? 95  GLN   A C    1 
ATOM   1466 O O    . GLN   A 1 98  ? 34.78336 -9.96485  0.40393  1.000 11.64176  ? 95  GLN   A O    1 
ATOM   1467 C CB   . GLN   A 1 98  ? 32.82887 -9.77255  3.07478  1.000 17.76106  ? 95  GLN   A CB   1 
ATOM   1468 C CG   . GLN   A 1 98  ? 33.87012 -8.72893  3.34565  1.000 12.24202  ? 95  GLN   A CG   1 
ATOM   1469 C CD   . GLN   A 1 98  ? 33.38180 -7.32836  3.00997  1.000 18.71623  ? 95  GLN   A CD   1 
ATOM   1470 O OE1  . GLN   A 1 98  ? 32.36380 -7.15899  2.34306  1.000 17.24766  ? 95  GLN   A OE1  1 
ATOM   1471 N NE2  . GLN   A 1 98  ? 34.09465 -6.32122  3.49313  1.000 12.35499  ? 95  GLN   A NE2  1 
ATOM   1472 H H    . GLN   A 1 98  ? 31.25045 -11.36659 2.14913  1.000 15.93170  ? 95  GLN   A H    1 
ATOM   1473 H HA   . GLN   A 1 98  ? 32.47773 -9.29535  1.10903  1.000 14.04247  ? 95  GLN   A HA   1 
ATOM   1474 H HB2  . GLN   A 1 98  ? 31.98059 -9.43905  3.40660  1.000 21.39886  ? 95  GLN   A HB2  1 
ATOM   1475 H HB3  . GLN   A 1 98  ? 33.08091 -10.57580 3.55660  1.000 21.39886  ? 95  GLN   A HB3  1 
ATOM   1476 H HG2  . GLN   A 1 98  ? 34.10424 -8.74986  4.28674  1.000 14.77600  ? 95  GLN   A HG2  1 
ATOM   1477 H HG3  . GLN   A 1 98  ? 34.65379 -8.91348  2.80463  1.000 14.77600  ? 95  GLN   A HG3  1 
ATOM   1478 H HE21 . GLN   A 1 98  ? 34.79335 -6.47842  3.96928  1.000 14.91157  ? 95  GLN   A HE21 1 
ATOM   1479 H HE22 . GLN   A 1 98  ? 33.85860 -5.51039  3.33056  1.000 14.91157  ? 95  GLN   A HE22 1 
ATOM   1480 N N    . GLU   A 1 99  ? 34.22007 -11.96249 1.26755  1.000 11.46558  ? 96  GLU   A N    1 
ATOM   1481 C CA   . GLU   A 1 99  ? 35.39139 -12.60360 0.68989  1.000 13.65349  ? 96  GLU   A CA   1 
ATOM   1482 C C    . GLU   A 1 99  ? 35.35069 -12.53120 -0.84193 1.000 19.14457  ? 96  GLU   A C    1 
ATOM   1483 O O    . GLU   A 1 99  ? 36.34071 -12.15595 -1.47955 1.000 16.49569  ? 96  GLU   A O    1 
ATOM   1484 C CB   . GLU   A 1 99  ? 35.47757 -14.05152 1.18750  1.000 19.45423  ? 96  GLU   A CB   1 
ATOM   1485 C CG   . GLU   A 1 99  ? 36.83915 -14.73498 0.96743  1.000 21.58184  ? 96  GLU   A CG   1 
ATOM   1486 C CD   . GLU   A 1 99  ? 36.87786 -16.18520 1.49224  1.000 20.33478  ? 96  GLU   A CD   1 
ATOM   1487 O OE1  . GLU   A 1 99  ? 35.82469 -16.87121 1.50545  1.000 24.26314  ? 96  GLU   A OE1  1 
ATOM   1488 O OE2  . GLU   A 1 99  ? 37.97166 -16.62856 1.89025  1.000 22.29700  ? 96  GLU   A OE2  1 
ATOM   1489 H H    . GLU   A 1 99  ? 33.73114 -12.47391 1.75642  1.000 13.84428  ? 96  GLU   A H    1 
ATOM   1490 H HA   . GLU   A 1 99  ? 36.19631 -12.14658 0.97994  1.000 16.46977  ? 96  GLU   A HA   1 
ATOM   1491 H HB2  . GLU   A 1 99  ? 35.29878 -14.05964 2.14084  1.000 23.43066  ? 96  GLU   A HB2  1 
ATOM   1492 H HB3  . GLU   A 1 99  ? 34.80946 -14.57700 0.72017  1.000 23.43066  ? 96  GLU   A HB3  1 
ATOM   1493 H HG2  . GLU   A 1 99  ? 37.03124 -14.75593 0.01687  1.000 25.98379  ? 96  GLU   A HG2  1 
ATOM   1494 H HG3  . GLU   A 1 99  ? 37.52406 -14.23021 1.43326  1.000 25.98379  ? 96  GLU   A HG3  1 
ATOM   1495 N N    . ASN   A 1 100 ? 34.19441 -12.82169 -1.44721 1.000 15.32566  ? 97  ASN   A N    1 
ATOM   1496 C CA   . ASN   A 1 100 ? 34.12015 -12.87256 -2.90677 1.000 26.30040  ? 97  ASN   A CA   1 
ATOM   1497 C C    . ASN   A 1 100 ? 34.39560 -11.51359 -3.53307 1.000 25.36247  ? 97  ASN   A C    1 
ATOM   1498 O O    . ASN   A 1 100 ? 35.04072 -11.42773 -4.58714 1.000 26.24655  ? 97  ASN   A O    1 
ATOM   1499 C CB   . ASN   A 1 100 ? 32.74879 -13.37820 -3.34217 1.000 23.22737  ? 97  ASN   A CB   1 
ATOM   1500 C CG   . ASN   A 1 100 ? 32.58997 -14.87113 -3.13114 1.000 57.71070  ? 97  ASN   A CG   1 
ATOM   1501 O OD1  . ASN   A 1 100 ? 33.57251 -15.62168 -3.14976 1.000 42.04062  ? 97  ASN   A OD1  1 
ATOM   1502 N ND2  . ASN   A 1 100 ? 31.35035 -15.31296 -2.92145 1.000 44.59720  ? 97  ASN   A ND2  1 
ATOM   1503 H H    . ASN   A 1 100 ? 33.45414 -12.98971 -1.04300 1.000 18.47637  ? 97  ASN   A H    1 
ATOM   1504 H HA   . ASN   A 1 100 ? 34.79531 -13.49255 -3.22405 1.000 31.64606  ? 97  ASN   A HA   1 
ATOM   1505 H HB2  . ASN   A 1 100 ? 32.06454 -12.92603 -2.82425 1.000 27.95843  ? 97  ASN   A HB2  1 
ATOM   1506 H HB3  . ASN   A 1 100 ? 32.62705 -13.19256 -4.28643 1.000 27.95843  ? 97  ASN   A HB3  1 
ATOM   1507 H HD21 . ASN   A 1 100 ? 31.20826 -16.15186 -2.79635 1.000 53.60223  ? 97  ASN   A HD21 1 
ATOM   1508 H HD22 . ASN   A 1 100 ? 30.69245 -14.75919 -2.91123 1.000 53.60223  ? 97  ASN   A HD22 1 
ATOM   1509 N N    . ARG   A 1 101 ? 33.89406 -10.44105 -2.92147 1.000 16.56256  ? 98  ARG   A N    1 
ATOM   1510 C CA   . ARG   A 1 101 ? 34.12212 -9.10735  -3.45386 1.000 17.30247  ? 98  ARG   A CA   1 
ATOM   1511 C C    . ARG   A 1 101 ? 35.42091 -8.50565  -2.95720 1.000 18.73078  ? 98  ARG   A C    1 
ATOM   1512 O O    . ARG   A 1 101 ? 35.70079 -7.33417  -3.23966 1.000 23.77376  ? 98  ARG   A O    1 
ATOM   1513 C CB   . ARG   A 1 101 ? 32.96188 -8.18531  -3.12257 1.000 23.83013  ? 98  ARG   A CB   1 
ATOM   1514 C CG   . ARG   A 1 101 ? 32.74544 -7.92875  -1.67616 1.000 36.21799  ? 98  ARG   A CG   1 
ATOM   1515 C CD   . ARG   A 1 101 ? 31.58539 -6.95375  -1.49648 1.000 42.45778  ? 98  ARG   A CD   1 
ATOM   1516 N NE   . ARG   A 1 101 ? 31.91867 -5.63884  -2.02918 1.000 44.65354  ? 98  ARG   A NE   1 
ATOM   1517 C CZ   . ARG   A 1 101 ? 32.57799 -4.71036  -1.34816 1.000 63.79891  ? 98  ARG   A CZ   1 
ATOM   1518 N NH1  . ARG   A 1 101 ? 32.97979 -4.92029  -0.09860 1.000 30.08742  ? 98  ARG   A NH1  1 
ATOM   1519 N NH2  . ARG   A 1 101 ? 32.83775 -3.54181  -1.93088 1.000 58.67214  ? 98  ARG   A NH2  1 
ATOM   1520 H H    A ARG   A 1 101 ? 33.42266 -10.46478 -2.20257 0.410 19.96066  ? 98  ARG   A H    1 
ATOM   1521 H H    B ARG   A 1 101 ? 33.42266 -10.46478 -2.20257 0.590 19.96066  ? 98  ARG   A H    1 
ATOM   1522 H HA   . ARG   A 1 101 ? 34.16643 -9.16933  -4.42087 1.000 20.84855  ? 98  ARG   A HA   1 
ATOM   1523 H HB2  . ARG   A 1 101 ? 33.12197 -7.32815  -3.54748 1.000 28.68174  ? 98  ARG   A HB2  1 
ATOM   1524 H HB3  . ARG   A 1 101 ? 32.14786 -8.58142  -3.47094 1.000 28.68174  ? 98  ARG   A HB3  1 
ATOM   1525 H HG2  . ARG   A 1 101 ? 32.52881 -8.75920  -1.22414 1.000 43.54717  ? 98  ARG   A HG2  1 
ATOM   1526 H HG3  . ARG   A 1 101 ? 33.54458 -7.53876  -1.28862 1.000 43.54717  ? 98  ARG   A HG3  1 
ATOM   1527 H HD2  . ARG   A 1 101 ? 30.80687 -7.28789  -1.96887 1.000 51.03492  ? 98  ARG   A HD2  1 
ATOM   1528 H HD3  . ARG   A 1 101 ? 31.38556 -6.86051  -0.55188 1.000 51.03492  ? 98  ARG   A HD3  1 
ATOM   1529 H HE   . ARG   A 1 101 ? 31.67352 -5.45374  -2.83244 1.000 53.66983  ? 98  ARG   A HE   1 
ATOM   1530 H HH11 . ARG   A 1 101 ? 32.81367 -5.67132  0.28607  1.000 36.19049  ? 98  ARG   A HH11 1 
ATOM   1531 H HH12 . ARG   A 1 101 ? 33.40587 -4.30509  0.32518  1.000 36.19049  ? 98  ARG   A HH12 1 
ATOM   1532 H HH21 . ARG   A 1 101 ? 32.57897 -3.39692  -2.73812 1.000 70.49215  ? 98  ARG   A HH21 1 
ATOM   1533 H HH22 . ARG   A 1 101 ? 33.26432 -2.93188  -1.50004 1.000 70.49215  ? 98  ARG   A HH22 1 
ATOM   1534 N N    . LYS   A 1 102 ? 36.22111 -9.28129  -2.22552 1.000 22.34312  ? 99  LYS   A N    1 
ATOM   1535 C CA   . LYS   A 1 102 ? 37.55749 -8.84804  -1.81240 1.000 19.51283  ? 99  LYS   A CA   1 
ATOM   1536 C C    . LYS   A 1 102 ? 37.49557 -7.65334  -0.86842 1.000 19.12089  ? 99  LYS   A C    1 
ATOM   1537 O O    . LYS   A 1 102 ? 38.33712 -6.75764  -0.90388 1.000 20.20510  ? 99  LYS   A O    1 
ATOM   1538 C CB   . LYS   A 1 102 ? 38.41742 -8.54820  -3.03863 1.000 26.69059  ? 99  LYS   A CB   1 
ATOM   1539 C CG   . LYS   A 1 102 ? 38.64443 -9.82330  -3.87430 1.000 40.29088  ? 99  LYS   A CG   1 
ATOM   1540 C CD   . LYS   A 1 102 ? 39.22752 -9.52070  -5.23957 1.000 63.40026  ? 99  LYS   A CD   1 
ATOM   1541 C CE   . LYS   A 1 102 ? 40.73502 -9.34343  -5.18004 1.000 74.55759  ? 99  LYS   A CE   1 
ATOM   1542 N NZ   . LYS   A 1 102 ? 41.25967 -8.81546  -6.47359 1.000 84.27188  ? 99  LYS   A NZ   1 
ATOM   1543 H H    . LYS   A 1 102 ? 36.01131 -10.06964 -1.95333 1.000 26.89733  ? 99  LYS   A H    1 
ATOM   1544 H HA   . LYS   A 1 102 ? 37.98189 -9.56260  -1.31221 1.000 23.50098  ? 99  LYS   A HA   1 
ATOM   1545 H HB2  . LYS   A 1 102 ? 37.96983 -7.89096  -3.59415 1.000 32.11429  ? 99  LYS   A HB2  1 
ATOM   1546 H HB3  . LYS   A 1 102 ? 39.28011 -8.20894  -2.75303 1.000 32.11429  ? 99  LYS   A HB3  1 
ATOM   1547 H HG2  . LYS   A 1 102 ? 39.26237 -10.40539 -3.40502 1.000 48.43464  ? 99  LYS   A HG2  1 
ATOM   1548 H HG3  . LYS   A 1 102 ? 37.79561 -10.27493 -4.00253 1.000 48.43464  ? 99  LYS   A HG3  1 
ATOM   1549 H HD2  . LYS   A 1 102 ? 39.03140 -10.25535 -5.84184 1.000 76.16590  ? 99  LYS   A HD2  1 
ATOM   1550 H HD3  . LYS   A 1 102 ? 38.83814 -8.69994  -5.57963 1.000 76.16590  ? 99  LYS   A HD3  1 
ATOM   1551 H HE2  . LYS   A 1 102 ? 40.95923 -8.71375  -4.47709 1.000 89.55470  ? 99  LYS   A HE2  1 
ATOM   1552 H HE3  . LYS   A 1 102 ? 41.15484 -10.20005 -5.00440 1.000 89.55470  ? 99  LYS   A HE3  1 
ATOM   1553 H HZ1  . LYS   A 1 102 ? 42.14786 -8.76657  -6.44459 1.000 101.21184 ? 99  LYS   A HZ1  1 
ATOM   1554 H HZ2  . LYS   A 1 102 ? 41.02168 -9.35389  -7.14108 1.000 101.21184 ? 99  LYS   A HZ2  1 
ATOM   1555 H HZ3  . LYS   A 1 102 ? 40.93052 -8.00284  -6.62661 1.000 101.21184 ? 99  LYS   A HZ3  1 
ATOM   1556 N N    . GLY   A 1 103 ? 36.51487 -7.65371  -0.02255 1.000 12.66698  ? 100 GLY   A N    1 
ATOM   1557 C CA   . GLY   A 1 103 ? 36.46826 -6.68591  1.04168  1.000 13.00498  ? 100 GLY   A CA   1 
ATOM   1558 C C    . GLY   A 1 103 ? 37.17525 -7.19727  2.28852  1.000 13.72539  ? 100 GLY   A C    1 
ATOM   1559 O O    . GLY   A 1 103 ? 37.39299 -8.39390  2.45684  1.000 11.96177  ? 100 GLY   A O    1 
ATOM   1560 H H    . GLY   A 1 103 ? 35.85472 -8.20473  -0.03590 1.000 15.28596  ? 100 GLY   A H    1 
ATOM   1561 H HA2  . GLY   A 1 103 ? 36.90027 -5.86630  0.75445  1.000 15.69156  ? 100 GLY   A HA2  1 
ATOM   1562 H HA3  . GLY   A 1 103 ? 35.54424 -6.49403  1.26591  1.000 15.69156  ? 100 GLY   A HA3  1 
ATOM   1563 N N    . LEU   A 1 104 ? 37.54895 -6.25358  3.14552  1.000 9.68156   ? 101 LEU   A N    1 
ATOM   1564 C CA   . LEU   A 1 104 ? 38.27768 -6.56851  4.36622  1.000 10.29739  ? 101 LEU   A CA   1 
ATOM   1565 C C    . LEU   A 1 104 ? 37.39581 -7.24752  5.41186  1.000 10.13803  ? 101 LEU   A C    1 
ATOM   1566 O O    . LEU   A 1 104 ? 36.21662 -6.92015  5.59350  1.000 10.60430  ? 101 LEU   A O    1 
ATOM   1567 C CB   . LEU   A 1 104 ? 38.87785 -5.28572  4.93875  1.000 6.71860   ? 101 LEU   A CB   1 
ATOM   1568 C CG   . LEU   A 1 104 ? 39.74996 -5.39355  6.17952  1.000 18.76604  ? 101 LEU   A CG   1 
ATOM   1569 C CD1  . LEU   A 1 104 ? 40.93507 -6.28362  5.84208  1.000 21.04255  ? 101 LEU   A CD1  1 
ATOM   1570 C CD2  . LEU   A 1 104 ? 40.17966 -4.00935  6.66362  1.000 20.76465  ? 101 LEU   A CD2  1 
ATOM   1571 H H    . LEU   A 1 104 ? 37.39103 -5.41455  3.04211  1.000 11.70346  ? 101 LEU   A H    1 
ATOM   1572 H HA   . LEU   A 1 104 ? 38.98813 -7.19418  4.15481  1.000 12.44245  ? 101 LEU   A HA   1 
ATOM   1573 H HB2  . LEU   A 1 104 ? 39.42679 -4.88391  4.24729  1.000 8.14791   ? 101 LEU   A HB2  1 
ATOM   1574 H HB3  . LEU   A 1 104 ? 38.14386 -4.69352  5.16558  1.000 8.14791   ? 101 LEU   A HB3  1 
ATOM   1575 H HG   . LEU   A 1 104 ? 39.26248 -5.79043  6.91827  1.000 22.60483  ? 101 LEU   A HG   1 
ATOM   1576 H HD11 . LEU   A 1 104 ? 41.69994 -6.00440  6.36925  1.000 25.33664  ? 101 LEU   A HD11 1 
ATOM   1577 H HD12 . LEU   A 1 104 ? 40.70831 -7.20360  6.04973  1.000 25.33664  ? 101 LEU   A HD12 1 
ATOM   1578 H HD13 . LEU   A 1 104 ? 41.13560 -6.19762  4.89694  1.000 25.33664  ? 101 LEU   A HD13 1 
ATOM   1579 H HD21 . LEU   A 1 104 ? 40.68380 -4.10511  7.48676  1.000 25.00317  ? 101 LEU   A HD21 1 
ATOM   1580 H HD22 . LEU   A 1 104 ? 40.73281 -3.59452  5.98330  1.000 25.00317  ? 101 LEU   A HD22 1 
ATOM   1581 H HD23 . LEU   A 1 104 ? 39.38877 -3.47023  6.82092  1.000 25.00317  ? 101 LEU   A HD23 1 
ATOM   1582 N N    . ILE   A 1 105 ? 37.98719 -8.21421  6.09940  1.000 8.61669   ? 102 ILE   A N    1 
ATOM   1583 C CA   . ILE   A 1 105 ? 37.34712 -8.94757  7.18811  1.000 8.54809   ? 102 ILE   A CA   1 
ATOM   1584 C C    . ILE   A 1 105 ? 38.26587 -8.85787  8.39521  1.000 8.20554   ? 102 ILE   A C    1 
ATOM   1585 O O    . ILE   A 1 105 ? 39.46225 -9.15088  8.28255  1.000 6.76171   ? 102 ILE   A O    1 
ATOM   1586 C CB   . ILE   A 1 105 ? 37.07941 -10.41878 6.82686  1.000 9.92656   ? 102 ILE   A CB   1 
ATOM   1587 C CG1  . ILE   A 1 105 ? 36.07107 -10.47124 5.67604  1.000 12.49433  ? 102 ILE   A CG1  1 
ATOM   1588 C CG2  . ILE   A 1 105 ? 36.59137 -11.16585 8.06097  1.000 11.68607  ? 102 ILE   A CG2  1 
ATOM   1589 C CD1  . ILE   A 1 105 ? 35.77461 -11.88451 5.17349  1.000 16.37280  ? 102 ILE   A CD1  1 
ATOM   1590 H H    . ILE   A 1 105 ? 38.79257 -8.47582  5.94931  1.000 10.42562  ? 102 ILE   A H    1 
ATOM   1591 H HA   . ILE   A 1 105 ? 36.49465 -8.53583  7.39948  1.000 10.34329  ? 102 ILE   A HA   1 
ATOM   1592 H HB   . ILE   A 1 105 ? 37.89460 -10.85234 6.52956  1.000 11.99745  ? 102 ILE   A HB   1 
ATOM   1593 H HG12 . ILE   A 1 105 ? 35.23452 -10.08374 5.97760  1.000 15.07878  ? 102 ILE   A HG12 1 
ATOM   1594 H HG13 . ILE   A 1 105 ? 36.42341 -9.96071  4.93030  1.000 15.07878  ? 102 ILE   A HG13 1 
ATOM   1595 H HG21 . ILE   A 1 105 ? 36.30337 -12.05428 7.79897  1.000 14.10887  ? 102 ILE   A HG21 1 
ATOM   1596 H HG22 . ILE   A 1 105 ? 37.31836 -11.22883 8.70004  1.000 14.10887  ? 102 ILE   A HG22 1 
ATOM   1597 H HG23 . ILE   A 1 105 ? 35.84878 -10.67918 8.45162  1.000 14.10887  ? 102 ILE   A HG23 1 
ATOM   1598 H HD11 . ILE   A 1 105 ? 35.20339 -12.33459 5.81538  1.000 19.73294  ? 102 ILE   A HD11 1 
ATOM   1599 H HD12 . ILE   A 1 105 ? 35.32643 -11.82694 4.31516  1.000 19.73294  ? 102 ILE   A HD12 1 
ATOM   1600 H HD13 . ILE   A 1 105 ? 36.61032 -12.36770 5.07853  1.000 19.73294  ? 102 ILE   A HD13 1 
ATOM   1601 N N    . ALA   A 1 106 ? 37.72472 -8.40471  9.53083  1.000 5.87204   ? 103 ALA   A N    1 
ATOM   1602 C CA   . ALA   A 1 106 ? 38.51905 -8.11974  10.72293 1.000 6.63041   ? 103 ALA   A CA   1 
ATOM   1603 C C    . ALA   A 1 106 ? 37.87635 -8.84018  11.90027 1.000 5.79442   ? 103 ALA   A C    1 
ATOM   1604 O O    . ALA   A 1 106 ? 36.66638 -8.71765  12.11940 1.000 6.74026   ? 103 ALA   A O    1 
ATOM   1605 C CB   . ALA   A 1 106 ? 38.59766 -6.60436  10.99676 1.000 6.10343   ? 103 ALA   A CB   1 
ATOM   1606 H H    . ALA   A 1 106 ? 36.88447 -8.25296  9.63350  1.000 7.13203   ? 103 ALA   A H    1 
ATOM   1607 H HA   . ALA   A 1 106 ? 39.42512 -8.44645  10.60801 1.000 8.04207   ? 103 ALA   A HA   1 
ATOM   1608 H HB1  . ALA   A 1 106 ? 39.20271 -6.44849  11.73873 1.000 7.40971   ? 103 ALA   A HB1  1 
ATOM   1609 H HB2  . ALA   A 1 106 ? 38.92681 -6.15645  10.20181 1.000 7.40971   ? 103 ALA   A HB2  1 
ATOM   1610 H HB3  . ALA   A 1 106 ? 37.71175 -6.27705  11.21798 1.000 7.40971   ? 103 ALA   A HB3  1 
ATOM   1611 N N    . ALA   A 1 107 ? 38.67816 -9.59743  12.64807 1.000 4.10435   ? 104 ALA   A N    1 
ATOM   1612 C CA   . ALA   A 1 107 ? 38.18487 -10.33711 13.79945 1.000 2.93201   ? 104 ALA   A CA   1 
ATOM   1613 C C    . ALA   A 1 107 ? 39.24746 -10.33256 14.89336 1.000 1.98885   ? 104 ALA   A C    1 
ATOM   1614 O O    . ALA   A 1 107 ? 40.45653 -10.36616 14.62630 1.000 3.90114   ? 104 ALA   A O    1 
ATOM   1615 C CB   . ALA   A 1 107 ? 37.80023 -11.76792 13.43808 1.000 1.39405   ? 104 ALA   A CB   1 
ATOM   1616 H H    . ALA   A 1 107 ? 39.52011 -9.69742  12.50410 1.000 5.01081   ? 104 ALA   A H    1 
ATOM   1617 H HA   . ALA   A 1 107 ? 37.39248 -9.89969  14.14830 1.000 3.60400   ? 104 ALA   A HA   1 
ATOM   1618 H HB1  . ALA   A 1 107 ? 37.47635 -12.21841 14.23373 1.000 1.75845   ? 104 ALA   A HB1  1 
ATOM   1619 H HB2  . ALA   A 1 107 ? 37.10377 -11.74685 12.76324 1.000 1.75845   ? 104 ALA   A HB2  1 
ATOM   1620 H HB3  . ALA   A 1 107 ? 38.58162 -12.22736 13.09276 1.000 1.75845   ? 104 ALA   A HB3  1 
ATOM   1621 N N    . ILE   A 1 108 ? 38.78878 -10.27549 16.13821 1.000 4.60091   ? 105 ILE   A N    1 
ATOM   1622 C CA   . ILE   A 1 108 ? 39.69137 -10.10383 17.26981 1.000 3.53736   ? 105 ILE   A CA   1 
ATOM   1623 C C    . ILE   A 1 108 ? 39.37907 -11.11162 18.37751 1.000 1.59943   ? 105 ILE   A C    1 
ATOM   1624 O O    . ILE   A 1 108 ? 38.21908 -11.46082 18.62466 1.000 2.70853   ? 105 ILE   A O    1 
ATOM   1625 C CB   . ILE   A 1 108 ? 39.63533 -8.64782  17.78450 1.000 4.27086   ? 105 ILE   A CB   1 
ATOM   1626 C CG1  . ILE   A 1 108 ? 40.59889 -8.46130  18.96387 1.000 0.59922   ? 105 ILE   A CG1  1 
ATOM   1627 C CG2  . ILE   A 1 108 ? 38.21033 -8.29963  18.27614 1.000 3.07390   ? 105 ILE   A CG2  1 
ATOM   1628 C CD1  . ILE   A 1 108 ? 40.91154 -7.04260  19.29924 1.000 4.28805   ? 105 ILE   A CD1  1 
ATOM   1629 H H    . ILE   A 1 108 ? 37.95791 -10.33394 16.35229 1.000 5.60667   ? 105 ILE   A H    1 
ATOM   1630 H HA   . ILE   A 1 108 ? 40.59622 -10.30812 16.98623 1.000 4.33042   ? 105 ILE   A HA   1 
ATOM   1631 H HB   . ILE   A 1 108 ? 39.88715 -8.06899  17.04799 1.000 5.21062   ? 105 ILE   A HB   1 
ATOM   1632 H HG12 . ILE   A 1 108 ? 40.20326 -8.86648  19.75140 1.000 0.80465   ? 105 ILE   A HG12 1 
ATOM   1633 H HG13 . ILE   A 1 108 ? 41.43631 -8.90138  18.74950 1.000 0.80465   ? 105 ILE   A HG13 1 
ATOM   1634 H HG21 . ILE   A 1 108 ? 38.15806 -7.34545  18.44263 1.000 3.77426   ? 105 ILE   A HG21 1 
ATOM   1635 H HG22 . ILE   A 1 108 ? 37.57001 -8.55169  17.59251 1.000 3.77426   ? 105 ILE   A HG22 1 
ATOM   1636 H HG23 . ILE   A 1 108 ? 38.03030 -8.78852  19.09436 1.000 3.77426   ? 105 ILE   A HG23 1 
ATOM   1637 H HD11 . ILE   A 1 108 ? 41.55663 -7.02407  20.02341 1.000 5.23125   ? 105 ILE   A HD11 1 
ATOM   1638 H HD12 . ILE   A 1 108 ? 41.28149 -6.60697  18.51548 1.000 5.23125   ? 105 ILE   A HD12 1 
ATOM   1639 H HD13 . ILE   A 1 108 ? 40.09519 -6.59527  19.57193 1.000 5.23125   ? 105 ILE   A HD13 1 
HETATM 1640 C C    . A1A7V A 1 109 ? 39.84962 -13.84163 19.85937 1.000 4.29356   ? 106 A1A7V A C    1 
HETATM 1641 N N    . A1A7V A 1 109 ? 40.44610 -11.65329 18.96446 1.000 1.83049   ? 106 A1A7V A N    1 
HETATM 1642 O O    . A1A7V A 1 109 ? 40.56362 -14.67182 19.28745 1.000 3.66376   ? 106 A1A7V A O    1 
HETATM 1643 C CA   . A1A7V A 1 109 ? 40.39911 -12.45628 20.18126 1.000 1.75421   ? 106 A1A7V A CA   1 
HETATM 1644 C CB   . A1A7V A 1 109 ? 39.58098 -11.77840 21.28450 1.000 3.66677   ? 106 A1A7V A CB   1 
HETATM 1645 S SG   . A1A7V A 1 109 ? 40.09106 -12.42053 22.91176 1.000 5.41491   ? 106 A1A7V A SG   1 
HETATM 1646 C C1   . A1A7V A 1 109 ? 38.48681 -12.65838 23.62201 0.806 1.78963   ? 106 A1A7V A C1   1 
HETATM 1647 O O1   . A1A7V A 1 109 ? 37.64411 -11.83776 23.43314 0.806 13.17448  ? 106 A1A7V A O1   1 
HETATM 1648 C C2   . A1A7V A 1 109 ? 38.13937 -13.86196 24.49134 0.806 29.16393  ? 106 A1A7V A C2   1 
HETATM 1649 O O2   . A1A7V A 1 109 ? 36.91607 -14.30989 23.94137 0.806 22.50735  ? 106 A1A7V A O2   1 
HETATM 1650 C C3   . A1A7V A 1 109 ? 39.16851 -14.99905 24.32410 0.806 27.82765  ? 106 A1A7V A C3   1 
HETATM 1651 H H    . A1A7V A 1 109 ? 41.24629 -11.56528 18.66189 1.000 2.28218   ? 106 A1A7V A H    1 
HETATM 1652 H HA   . A1A7V A 1 109 ? 41.29783 -12.54961 20.53410 1.000 2.19063   ? 106 A1A7V A HA   1 
HETATM 1653 H HB3  . A1A7V A 1 109 ? 38.63824 -11.96654 21.15514 1.000 4.48570   ? 106 A1A7V A HB3  1 
HETATM 1654 H HB2  . A1A7V A 1 109 ? 39.73407 -10.82078 21.26377 1.000 4.48570   ? 106 A1A7V A HB2  1 
HETATM 1655 H H20  . A1A7V A 1 109 ? 38.10245 -13.59938 25.57435 0.806 35.08230  ? 106 A1A7V A H20  1 
HETATM 1656 H HO2  . A1A7V A 1 109 ? 37.12687 -14.73065 23.10792 0.806 27.09440  ? 106 A1A7V A HO2  1 
HETATM 1657 H H3B  . A1A7V A 1 109 ? 38.79055 -15.97214 24.65464 0.806 33.47877  ? 106 A1A7V A H3B  1 
HETATM 1658 H H3A  . A1A7V A 1 109 ? 40.08936 -14.83161 24.89244 0.806 33.47877  ? 106 A1A7V A H3A  1 
HETATM 1659 H H3   . A1A7V A 1 109 ? 39.48467 -15.14256 23.28560 0.806 33.47877  ? 106 A1A7V A H3   1 
ATOM   1660 N N    . ALA   A 1 110 ? 38.60975 -14.12505 20.23653 1.000 3.72514   ? 107 ALA   A N    1 
ATOM   1661 C CA   . ALA   A 1 110 ? 37.97379 -15.36264 19.80150 1.000 2.74311   ? 107 ALA   A CA   1 
ATOM   1662 C C    . ALA   A 1 110 ? 37.22882 -15.20707 18.48266 1.000 4.06704   ? 107 ALA   A C    1 
ATOM   1663 O O    . ALA   A 1 110 ? 36.87083 -16.21382 17.87226 1.000 3.55585   ? 107 ALA   A O    1 
ATOM   1664 C CB   . ALA   A 1 110 ? 36.99357 -15.88465 20.86682 1.000 7.72087   ? 107 ALA   A CB   1 
ATOM   1665 H H    . ALA   A 1 110 ? 38.12207 -13.62406 20.73731 1.000 4.55575   ? 107 ALA   A H    1 
ATOM   1666 H HA   . ALA   A 1 110 ? 38.66595 -16.03307 19.69043 1.000 3.37732   ? 107 ALA   A HA   1 
ATOM   1667 H HB1  . ALA   A 1 110 ? 36.54453 -16.67296 20.52357 1.000 9.35063   ? 107 ALA   A HB1  1 
ATOM   1668 H HB2  . ALA   A 1 110 ? 37.48980 -16.10972 21.66932 1.000 9.35063   ? 107 ALA   A HB2  1 
ATOM   1669 H HB3  . ALA   A 1 110 ? 36.34292 -15.19262 21.06342 1.000 9.35063   ? 107 ALA   A HB3  1 
ATOM   1670 N N    . GLY   A 1 111 ? 37.03647 -13.97543 18.01763 1.000 1.46322   ? 108 GLY   A N    1 
ATOM   1671 C CA   . GLY   A 1 111 ? 36.31241 -13.74308 16.78124 1.000 7.87328   ? 108 GLY   A CA   1 
ATOM   1672 C C    . GLY   A 1 111 ? 36.81888 -14.52074 15.59810 1.000 3.39592   ? 108 GLY   A C    1 
ATOM   1673 O O    . GLY   A 1 111 ? 36.00575 -14.98756 14.78004 1.000 7.18652   ? 108 GLY   A O    1 
ATOM   1674 H H    . GLY   A 1 111 ? 37.31697 -13.25934 18.40250 1.000 1.84145   ? 108 GLY   A H    1 
ATOM   1675 H HA2  . GLY   A 1 111 ? 35.38204 -13.98197 16.91626 1.000 9.53352   ? 108 GLY   A HA2  1 
ATOM   1676 H HA3  . GLY   A 1 111 ? 36.36757 -12.79997 16.56124 1.000 9.53352   ? 108 GLY   A HA3  1 
ATOM   1677 N N    . PRO   A 1 112 ? 38.12592 -14.70393 15.44421 1.000 1.62904   ? 109 PRO   A N    1 
ATOM   1678 C CA   . PRO   A 1 112 ? 38.60869 -15.38480 14.23723 1.000 3.60118   ? 109 PRO   A CA   1 
ATOM   1679 C C    . PRO   A 1 112 ? 38.08319 -16.79968 14.10612 1.000 4.29601   ? 109 PRO   A C    1 
ATOM   1680 O O    . PRO   A 1 112 ? 38.04962 -17.34362 12.98881 1.000 6.87728   ? 109 PRO   A O    1 
ATOM   1681 C CB   . PRO   A 1 112 ? 40.12549 -15.35369 14.39928 1.000 2.38493   ? 109 PRO   A CB   1 
ATOM   1682 C CG   . PRO   A 1 112 ? 40.38971 -14.11700 15.21624 1.000 3.97739   ? 109 PRO   A CG   1 
ATOM   1683 C CD   . PRO   A 1 112 ? 39.21669 -14.06420 16.19739 1.000 3.97651   ? 109 PRO   A CD   1 
ATOM   1684 H HA   . PRO   A 1 112 ? 38.37143 -14.88006 13.44360 1.000 4.40700   ? 109 PRO   A HA   1 
ATOM   1685 H HB2  . PRO   A 1 112 ? 40.42668 -16.15015 14.86385 1.000 2.94750   ? 109 PRO   A HB2  1 
ATOM   1686 H HB3  . PRO   A 1 112 ? 40.55167 -15.29561 13.52986 1.000 2.94750   ? 109 PRO   A HB3  1 
ATOM   1687 H HG2  . PRO   A 1 112 ? 41.23497 -14.19971 15.68486 1.000 4.85845   ? 109 PRO   A HG2  1 
ATOM   1688 H HG3  . PRO   A 1 112 ? 40.40304 -13.33414 14.64366 1.000 4.85845   ? 109 PRO   A HG3  1 
ATOM   1689 H HD2  . PRO   A 1 112 ? 39.41816 -14.56196 17.00520 1.000 4.85740   ? 109 PRO   A HD2  1 
ATOM   1690 H HD3  . PRO   A 1 112 ? 38.99242 -13.14712 16.42005 1.000 4.85740   ? 109 PRO   A HD3  1 
ATOM   1691 N N    . THR   A 1 113 ? 37.64444 -17.40614 15.20980 1.000 5.28247   ? 110 THR   A N    1 
ATOM   1692 C CA   . THR   A 1 113 ? 37.16742 -18.77548 15.11902 1.000 4.66036   ? 110 THR   A CA   1 
ATOM   1693 C C    . THR   A 1 113 ? 35.90214 -18.85459 14.29922 1.000 6.56640   ? 110 THR   A C    1 
ATOM   1694 O O    . THR   A 1 113 ? 35.60039 -19.91967 13.77043 1.000 7.51875   ? 110 THR   A O    1 
ATOM   1695 C CB   . THR   A 1 113 ? 36.92935 -19.38923 16.50507 1.000 8.80119   ? 110 THR   A CB   1 
ATOM   1696 O OG1  . THR   A 1 113 ? 35.84695 -18.74278 17.18032 1.000 9.94476   ? 110 THR   A OG1  1 
ATOM   1697 C CG2  . THR   A 1 113 ? 38.17227 -19.26412 17.34163 1.000 12.55724  ? 110 THR   A CG2  1 
ATOM   1698 H H    . THR   A 1 113 ? 37.61541 -17.05492 15.99427 1.000 6.42455   ? 110 THR   A H    1 
ATOM   1699 H HA   . THR   A 1 113 ? 37.85778 -19.31212 14.69911 1.000 5.67801   ? 110 THR   A HA   1 
ATOM   1700 H HB   . THR   A 1 113 ? 36.70409 -20.32619 16.39432 1.000 10.64701  ? 110 THR   A HB   1 
ATOM   1701 H HG1  . THR   A 1 113 ? 36.09112 -17.98861 17.45820 1.000 12.01930  ? 110 THR   A HG1  1 
ATOM   1702 H HG21 . THR   A 1 113 ? 38.30800 -18.33844 17.59776 1.000 15.15427  ? 110 THR   A HG21 1 
ATOM   1703 H HG22 . THR   A 1 113 ? 38.08821 -19.80351 18.14343 1.000 15.15427  ? 110 THR   A HG22 1 
ATOM   1704 H HG23 . THR   A 1 113 ? 38.94342 -19.56757 16.83750 1.000 15.15427  ? 110 THR   A HG23 1 
ATOM   1705 N N    . ALA   A 1 114 ? 35.17066 -17.74689 14.15559 1.000 3.39639   ? 111 ALA   A N    1 
ATOM   1706 C CA   . ALA   A 1 114 ? 34.00686 -17.76621 13.27663 1.000 4.28619   ? 111 ALA   A CA   1 
ATOM   1707 C C    . ALA   A 1 114 ? 34.42875 -17.93978 11.82530 1.000 8.45184   ? 111 ALA   A C    1 
ATOM   1708 O O    . ALA   A 1 114 ? 33.64301 -18.39150 10.97818 1.000 8.96123   ? 111 ALA   A O    1 
ATOM   1709 C CB   . ALA   A 1 114 ? 33.21643 -16.47431 13.44002 1.000 8.55102   ? 111 ALA   A CB   1 
ATOM   1710 H H    . ALA   A 1 114 ? 35.32388 -16.99543 14.54472 1.000 4.16125   ? 111 ALA   A H    1 
ATOM   1711 H HA   . ALA   A 1 114 ? 33.42968 -18.50616 13.52207 1.000 5.22901   ? 111 ALA   A HA   1 
ATOM   1712 H HB1  . ALA   A 1 114 ? 32.42421 -16.51606 12.88185 1.000 10.34681  ? 111 ALA   A HB1  1 
ATOM   1713 H HB2  . ALA   A 1 114 ? 32.96067 -16.37611 14.37052 1.000 10.34681  ? 111 ALA   A HB2  1 
ATOM   1714 H HB3  . ALA   A 1 114 ? 33.77282 -15.72729 13.16929 1.000 10.34681  ? 111 ALA   A HB3  1 
ATOM   1715 N N    . LEU   A 1 115 ? 35.65334 -17.54732 11.51568 1.000 2.27622   ? 112 LEU   A N    1 
ATOM   1716 C CA   . LEU   A 1 115 ? 36.13678 -17.68850 10.15335 1.000 2.73442   ? 112 LEU   A CA   1 
ATOM   1717 C C    . LEU   A 1 115 ? 36.30312 -19.14930 9.79899  1.000 10.42102  ? 112 LEU   A C    1 
ATOM   1718 O O    . LEU   A 1 115 ? 35.98337 -19.57701 8.68245  1.000 8.92368   ? 112 LEU   A O    1 
ATOM   1719 C CB   . LEU   A 1 115 ? 37.47163 -16.95940 9.99399  1.000 3.30831   ? 112 LEU   A CB   1 
ATOM   1720 C CG   . LEU   A 1 115 ? 37.43878 -15.47256 10.33086 1.000 10.48136  ? 112 LEU   A CG   1 
ATOM   1721 C CD1  . LEU   A 1 115 ? 38.77353 -14.84518 10.07204 1.000 14.05005  ? 112 LEU   A CD1  1 
ATOM   1722 C CD2  . LEU   A 1 115 ? 36.37356 -14.77824 9.53830  1.000 11.90767  ? 112 LEU   A CD2  1 
ATOM   1723 H H    . LEU   A 1 115 ? 36.21642 -17.20146 12.06606 1.000 2.81705   ? 112 LEU   A H    1 
ATOM   1724 H HA   . LEU   A 1 115 ? 35.49579 -17.28708 9.54597  1.000 3.36688   ? 112 LEU   A HA   1 
ATOM   1725 H HB2  . LEU   A 1 115 ? 38.12069 -17.37700 10.58155 1.000 4.05556   ? 112 LEU   A HB2  1 
ATOM   1726 H HB3  . LEU   A 1 115 ? 37.75779 -17.04277 9.07092  1.000 4.05556   ? 112 LEU   A HB3  1 
ATOM   1727 H HG   . LEU   A 1 115 ? 37.23284 -15.36805 11.27296 1.000 12.66322  ? 112 LEU   A HG   1 
ATOM   1728 H HD11 . LEU   A 1 115 ? 38.72069 -13.89717 10.27046 1.000 16.94565  ? 112 LEU   A HD11 1 
ATOM   1729 H HD12 . LEU   A 1 115 ? 39.43611 -15.26599 10.64195 1.000 16.94565  ? 112 LEU   A HD12 1 
ATOM   1730 H HD13 . LEU   A 1 115 ? 39.00830 -14.97545 9.13993  1.000 16.94565  ? 112 LEU   A HD13 1 
ATOM   1731 H HD21 . LEU   A 1 115 ? 36.46398 -13.82006 9.65916  1.000 14.37479  ? 112 LEU   A HD21 1 
ATOM   1732 H HD22 . LEU   A 1 115 ? 36.47901 -15.00482 8.60105  1.000 14.37479  ? 112 LEU   A HD22 1 
ATOM   1733 H HD23 . LEU   A 1 115 ? 35.50412 -15.07081 9.85353  1.000 14.37479  ? 112 LEU   A HD23 1 
ATOM   1734 N N    . LEU   A 1 116 ? 36.82871 -19.92538 10.73855 1.000 5.52648   ? 113 LEU   A N    1 
ATOM   1735 C CA   . LEU   A 1 116 ? 36.98564 -21.34704 10.50419 1.000 10.48469  ? 113 LEU   A CA   1 
ATOM   1736 C C    . LEU   A 1 116 ? 35.63325 -22.00747 10.34829 1.000 11.27215  ? 113 LEU   A C    1 
ATOM   1737 O O    . LEU   A 1 116 ? 35.42366 -22.80905 9.43642  1.000 12.26815  ? 113 LEU   A O    1 
ATOM   1738 C CB   . LEU   A 1 116 ? 37.74384 -21.97398 11.66197 1.000 5.28271   ? 113 LEU   A CB   1 
ATOM   1739 C CG   . LEU   A 1 116 ? 37.83359 -23.50890 11.63626 1.000 10.74942  ? 113 LEU   A CG   1 
ATOM   1740 C CD1  . LEU   A 1 116 ? 38.63072 -23.99585 10.42733 1.000 5.81036   ? 113 LEU   A CD1  1 
ATOM   1741 C CD2  . LEU   A 1 116 ? 38.46121 -23.98799 12.92098 1.000 11.83515  ? 113 LEU   A CD2  1 
ATOM   1742 H H    . LEU   A 1 116 ? 37.09802 -19.65471 11.50914 1.000 6.71736   ? 113 LEU   A H    1 
ATOM   1743 H HA   . LEU   A 1 116 ? 37.49637 -21.48481 9.69113  1.000 12.66722  ? 113 LEU   A HA   1 
ATOM   1744 H HB2  . LEU   A 1 116 ? 38.65089 -21.63032 11.65420 1.000 6.42484   ? 113 LEU   A HB2  1 
ATOM   1745 H HB3  . LEU   A 1 116 ? 37.30112 -21.72322 12.48782 1.000 6.42484   ? 113 LEU   A HB3  1 
ATOM   1746 H HG   . LEU   A 1 116 ? 36.94318 -23.88561 11.55771 1.000 12.98489  ? 113 LEU   A HG   1 
ATOM   1747 H HD11 . LEU   A 1 116 ? 38.64512 -24.96574 10.42840 1.000 7.05801   ? 113 LEU   A HD11 1 
ATOM   1748 H HD12 . LEU   A 1 116 ? 38.20571 -23.67224 9.61766  1.000 7.05801   ? 113 LEU   A HD12 1 
ATOM   1749 H HD13 . LEU   A 1 116 ? 39.53563 -23.65153 10.48622 1.000 7.05801   ? 113 LEU   A HD13 1 
ATOM   1750 H HD21 . LEU   A 1 116 ? 38.54881 -24.95349 12.88881 1.000 14.28777  ? 113 LEU   A HD21 1 
ATOM   1751 H HD22 . LEU   A 1 116 ? 39.33578 -23.57950 13.01673 1.000 14.28777  ? 113 LEU   A HD22 1 
ATOM   1752 H HD23 . LEU   A 1 116 ? 37.89335 -23.73196 13.66454 1.000 14.28777  ? 113 LEU   A HD23 1 
ATOM   1753 N N    . ALA   A 1 117 ? 34.71309 -21.70323 11.26237 1.000 6.18064   ? 114 ALA   A N    1 
ATOM   1754 C CA   . ALA   A 1 117 ? 33.37063 -22.26283 11.19175 1.000 10.65433  ? 114 ALA   A CA   1 
ATOM   1755 C C    . ALA   A 1 117 ? 32.73880 -22.03901 9.82076  1.000 12.79102  ? 114 ALA   A C    1 
ATOM   1756 O O    . ALA   A 1 117 ? 32.00670 -22.88962 9.31035  1.000 12.05957  ? 114 ALA   A O    1 
ATOM   1757 C CB   . ALA   A 1 117 ? 32.51362 -21.62767 12.28378 1.000 12.97487  ? 114 ALA   A CB   1 
ATOM   1758 H H    . ALA   A 1 117 ? 34.84185 -21.17706 11.93033 1.000 7.50235   ? 114 ALA   A H    1 
ATOM   1759 H HA   . ALA   A 1 117 ? 33.41312 -23.22057 11.33955 1.000 12.87078  ? 114 ALA   A HA   1 
ATOM   1760 H HB1  . ALA   A 1 117 ? 31.61663 -21.99349 12.23408 1.000 15.65543  ? 114 ALA   A HB1  1 
ATOM   1761 H HB2  . ALA   A 1 117 ? 32.90491 -21.82752 13.14857 1.000 15.65543  ? 114 ALA   A HB2  1 
ATOM   1762 H HB3  . ALA   A 1 117 ? 32.48746 -20.66780 12.14643 1.000 15.65543  ? 114 ALA   A HB3  1 
ATOM   1763 N N    . HIS   A 1 118 ? 33.01254 -20.90139 9.20852  1.000 8.31398   ? 115 HIS   A N    1 
ATOM   1764 C CA   . HIS   A 1 118 ? 32.38806 -20.52351 7.95230  1.000 16.53108  ? 115 HIS   A CA   1 
ATOM   1765 C C    . HIS   A 1 118 ? 33.30840 -20.71768 6.75614  1.000 14.13798  ? 115 HIS   A C    1 
ATOM   1766 O O    . HIS   A 1 118 ? 32.96970 -20.27790 5.64933  1.000 8.58375   ? 115 HIS   A O    1 
ATOM   1767 C CB   . HIS   A 1 118 ? 31.93129 -19.07088 8.04091  1.000 9.66053   ? 115 HIS   A CB   1 
ATOM   1768 C CG   . HIS   A 1 118 ? 30.87552 -18.84793 9.06852  1.000 14.71640  ? 115 HIS   A CG   1 
ATOM   1769 N ND1  . HIS   A 1 118 ? 29.80969 -19.70406 9.23134  1.000 13.81925  ? 115 HIS   A ND1  1 
ATOM   1770 C CD2  . HIS   A 1 118 ? 30.73549 -17.88256 10.00674 1.000 12.97074  ? 115 HIS   A CD2  1 
ATOM   1771 C CE1  . HIS   A 1 118 ? 29.06026 -19.27930 10.23253 1.000 9.99419   ? 115 HIS   A CE1  1 
ATOM   1772 N NE2  . HIS   A 1 118 ? 29.59260 -18.16651 10.70962 1.000 7.74722   ? 115 HIS   A NE2  1 
ATOM   1773 H H    . HIS   A 1 118 ? 33.56919 -20.31765 9.50683  1.000 10.06236  ? 115 HIS   A H    1 
ATOM   1774 H HA   . HIS   A 1 118 ? 31.60850 -21.08106 7.80288  1.000 19.92289  ? 115 HIS   A HA   1 
ATOM   1775 H HB2  . HIS   A 1 118 ? 32.69292 -18.51585 8.27059  1.000 11.67822  ? 115 HIS   A HB2  1 
ATOM   1776 H HB3  . HIS   A 1 118 ? 31.57201 -18.80184 7.18100  1.000 11.67822  ? 115 HIS   A HB3  1 
ATOM   1777 H HD2  . HIS   A 1 118 ? 31.30666 -17.16237 10.14815 1.000 15.65047  ? 115 HIS   A HD2  1 
ATOM   1778 H HE1  . HIS   A 1 118 ? 28.28925 -19.69246 10.54836 1.000 12.07861  ? 115 HIS   A HE1  1 
ATOM   1779 H HE2  . HIS   A 1 118 ? 29.27376 -17.69711 11.35583 1.000 9.38225   ? 115 HIS   A HE2  1 
ATOM   1780 N N    . GLU   A 1 119 ? 34.47157 -21.34067 6.96475  1.000 11.17793  ? 116 GLU   A N    1 
ATOM   1781 C CA   . GLU   A 1 119 ? 35.38475 -21.71846 5.88828  1.000 12.65949  ? 116 GLU   A CA   1 
ATOM   1782 C C    . GLU   A 1 119 ? 35.83293 -20.48538 5.12758  1.000 13.91784  ? 116 GLU   A C    1 
ATOM   1783 O O    . GLU   A 1 119 ? 35.80741 -20.43671 3.89839  1.000 14.33435  ? 116 GLU   A O    1 
ATOM   1784 C CB   . GLU   A 1 119 ? 34.73980 -22.74856 4.95540  1.000 18.59158  ? 116 GLU   A CB   1 
ATOM   1785 C CG   . GLU   A 1 119 ? 34.32594 -24.01609 5.69448  1.000 28.96576  ? 116 GLU   A CG   1 
ATOM   1786 C CD   . GLU   A 1 119 ? 33.89867 -25.13732 4.76178  1.000 43.27772  ? 116 GLU   A CD   1 
ATOM   1787 O OE1  . GLU   A 1 119 ? 33.60207 -24.86541 3.57427  1.000 38.38509  ? 116 GLU   A OE1  1 
ATOM   1788 O OE2  . GLU   A 1 119 ? 33.87295 -26.29235 5.22448  1.000 35.26496  ? 116 GLU   A OE2  1 
ATOM   1789 H H    . GLU   A 1 119 ? 34.76032 -21.56064 7.74439  1.000 13.49910  ? 116 GLU   A H    1 
ATOM   1790 H HA   . GLU   A 1 119 ? 36.17328 -22.13292 6.27213  1.000 15.27697  ? 116 GLU   A HA   1 
ATOM   1791 H HB2  . GLU   A 1 119 ? 33.94718 -22.36040 4.55293  1.000 22.39548  ? 116 GLU   A HB2  1 
ATOM   1792 H HB3  . GLU   A 1 119 ? 35.37572 -22.99446 4.26545  1.000 22.39548  ? 116 GLU   A HB3  1 
ATOM   1793 H HG2  . GLU   A 1 119 ? 35.07730 -24.33418 6.21906  1.000 34.84449  ? 116 GLU   A HG2  1 
ATOM   1794 H HG3  . GLU   A 1 119 ? 33.57788 -23.81089 6.27689  1.000 34.84449  ? 116 GLU   A HG3  1 
ATOM   1795 N N    . ILE   A 1 120 ? 36.27226 -19.48904 5.88527  1.000 14.41873  ? 117 ILE   A N    1 
ATOM   1796 C CA   . ILE   A 1 120 ? 36.63662 -18.18944 5.34819  1.000 5.64304   ? 117 ILE   A CA   1 
ATOM   1797 C C    . ILE   A 1 120 ? 38.14885 -18.02668 5.40654  1.000 13.91588  ? 117 ILE   A C    1 
ATOM   1798 O O    . ILE   A 1 120 ? 38.75711 -18.15996 6.47704  1.000 9.31533   ? 117 ILE   A O    1 
ATOM   1799 C CB   . ILE   A 1 120 ? 35.94459 -17.05015 6.11745  1.000 8.44101   ? 117 ILE   A CB   1 
ATOM   1800 C CG1  . ILE   A 1 120 ? 34.42168 -17.15907 6.00895  1.000 17.73554  ? 117 ILE   A CG1  1 
ATOM   1801 C CG2  . ILE   A 1 120 ? 36.46790 -15.71100 5.61322  1.000 14.29867  ? 117 ILE   A CG2  1 
ATOM   1802 C CD1  . ILE   A 1 120 ? 33.88589 -16.98668 4.58908  1.000 17.58613  ? 117 ILE   A CD1  1 
ATOM   1803 H H    . ILE   A 1 120 ? 36.36977 -19.54587 6.73783  1.000 17.38806  ? 117 ILE   A H    1 
ATOM   1804 H HA   . ILE   A 1 120 ? 36.36578 -18.15454 4.41742  1.000 6.85724   ? 117 ILE   A HA   1 
ATOM   1805 H HB   . ILE   A 1 120 ? 36.15671 -17.12386 7.06109  1.000 10.21480  ? 117 ILE   A HB   1 
ATOM   1806 H HG12 . ILE   A 1 120 ? 34.14956 -18.03573 6.32251  1.000 21.36823  ? 117 ILE   A HG12 1 
ATOM   1807 H HG13 . ILE   A 1 120 ? 34.02056 -16.46992 6.56129  1.000 21.36823  ? 117 ILE   A HG13 1 
ATOM   1808 H HG21 . ILE   A 1 120 ? 35.85871 -15.00909 5.89088  1.000 17.24398  ? 117 ILE   A HG21 1 
ATOM   1809 H HG22 . ILE   A 1 120 ? 37.34772 -15.55361 5.99011  1.000 17.24398  ? 117 ILE   A HG22 1 
ATOM   1810 H HG23 . ILE   A 1 120 ? 36.52268 -15.73762 4.64514  1.000 17.24398  ? 117 ILE   A HG23 1 
ATOM   1811 H HD11 . ILE   A 1 120 ? 32.91674 -17.02110 4.61091  1.000 21.18894  ? 117 ILE   A HD11 1 
ATOM   1812 H HD12 . ILE   A 1 120 ? 34.17871 -16.12914 4.24299  1.000 21.18894  ? 117 ILE   A HD12 1 
ATOM   1813 H HD13 . ILE   A 1 120 ? 34.22986 -17.70288 4.03262  1.000 21.18894  ? 117 ILE   A HD13 1 
ATOM   1814 N N    . GLY   A 1 121 ? 38.74818 -17.71524 4.26182  1.000 10.71739  ? 118 GLY   A N    1 
ATOM   1815 C CA   . GLY   A 1 121 ? 40.14729 -17.32627 4.22613  1.000 9.67386   ? 118 GLY   A CA   1 
ATOM   1816 C C    . GLY   A 1 121 ? 41.16512 -18.41796 4.48967  1.000 11.83401  ? 118 GLY   A C    1 
ATOM   1817 O O    . GLY   A 1 121 ? 42.28329 -18.11578 4.94036  1.000 7.48662   ? 118 GLY   A O    1 
ATOM   1818 H H    . GLY   A 1 121 ? 38.36431 -17.72204 3.49228  1.000 12.94645  ? 118 GLY   A H    1 
ATOM   1819 H HA2  . GLY   A 1 121 ? 40.33831 -16.96099 3.34807  1.000 11.69421  ? 118 GLY   A HA2  1 
ATOM   1820 H HA3  . GLY   A 1 121 ? 40.28728 -16.63567 4.89275  1.000 11.69421  ? 118 GLY   A HA3  1 
ATOM   1821 N N    . PHE   A 1 122 ? 40.83188 -19.67782 4.20305  1.000 8.79349   ? 119 PHE   A N    1 
ATOM   1822 C CA   . PHE   A 1 122 ? 41.79932 -20.75355 4.41536  1.000 8.54089   ? 119 PHE   A CA   1 
ATOM   1823 C C    . PHE   A 1 122 ? 43.11539 -20.44078 3.70656  1.000 10.95550  ? 119 PHE   A C    1 
ATOM   1824 O O    . PHE   A 1 122 ? 43.13402 -19.95297 2.56965  1.000 6.96806   ? 119 PHE   A O    1 
ATOM   1825 C CB   . PHE   A 1 122 ? 41.24965 -22.10130 3.93439  1.000 13.89781  ? 119 PHE   A CB   1 
ATOM   1826 C CG   . PHE   A 1 122 ? 40.21103 -22.70460 4.84827  1.000 9.39087   ? 119 PHE   A CG   1 
ATOM   1827 C CD1  . PHE   A 1 122 ? 39.74275 -22.01702 5.96971  1.000 9.78963   ? 119 PHE   A CD1  1 
ATOM   1828 C CD2  . PHE   A 1 122 ? 39.70067 -23.97013 4.59129  1.000 12.69483  ? 119 PHE   A CD2  1 
ATOM   1829 C CE1  . PHE   A 1 122 ? 38.76353 -22.59309 6.79390  1.000 11.46856  ? 119 PHE   A CE1  1 
ATOM   1830 C CE2  . PHE   A 1 122 ? 38.73223 -24.53580 5.41838  1.000 12.68260  ? 119 PHE   A CE2  1 
ATOM   1831 C CZ   . PHE   A 1 122 ? 38.29010 -23.85835 6.52418  1.000 8.46927   ? 119 PHE   A CZ   1 
ATOM   1832 H H    . PHE   A 1 122 ? 40.07057 -19.92954 3.89217  1.000 10.63777  ? 119 PHE   A H    1 
ATOM   1833 H HA   . PHE   A 1 122 ? 41.96824 -20.83184 5.36732  1.000 10.33465  ? 119 PHE   A HA   1 
ATOM   1834 H HB2  . PHE   A 1 122 ? 40.83971 -21.97680 3.06413  1.000 16.76296  ? 119 PHE   A HB2  1 
ATOM   1835 H HB3  . PHE   A 1 122 ? 41.98478 -22.73062 3.86786  1.000 16.76296  ? 119 PHE   A HB3  1 
ATOM   1836 H HD1  . PHE   A 1 122 ? 40.08085 -21.17443 6.17123  1.000 11.83314  ? 119 PHE   A HD1  1 
ATOM   1837 H HD2  . PHE   A 1 122 ? 40.01000 -24.44770 3.85567  1.000 15.31938  ? 119 PHE   A HD2  1 
ATOM   1838 H HE1  . PHE   A 1 122 ? 38.43374 -22.11980 7.52337  1.000 13.84786  ? 119 PHE   A HE1  1 
ATOM   1839 H HE2  . PHE   A 1 122 ? 38.38514 -25.37531 5.21925  1.000 15.30470  ? 119 PHE   A HE2  1 
ATOM   1840 H HZ   . PHE   A 1 122 ? 37.66962 -24.25318 7.09339  1.000 10.24871  ? 119 PHE   A HZ   1 
ATOM   1841 N N    . GLY   A 1 123 ? 44.22604 -20.73845 4.39221  1.000 10.58930  ? 120 GLY   A N    1 
ATOM   1842 C CA   . GLY   A 1 123 ? 45.54548 -20.47946 3.87677  1.000 6.25675   ? 120 GLY   A CA   1 
ATOM   1843 C C    . GLY   A 1 123 ? 46.19514 -19.21061 4.37308  1.000 13.89377  ? 120 GLY   A C    1 
ATOM   1844 O O    . GLY   A 1 123 ? 47.37940 -19.01742 4.12720  1.000 12.20341  ? 120 GLY   A O    1 
ATOM   1845 H H    . GLY   A 1 123 ? 44.22574 -21.09826 5.17333  1.000 12.79275  ? 120 GLY   A H    1 
ATOM   1846 H HA2  . GLY   A 1 123 ? 46.12295 -21.21979 4.12036  1.000 7.59368   ? 120 GLY   A HA2  1 
ATOM   1847 H HA3  . GLY   A 1 123 ? 45.49384 -20.42415 2.90973  1.000 7.59368   ? 120 GLY   A HA3  1 
ATOM   1848 N N    . SER   A 1 124 ? 45.45299 -18.34195 5.04305  1.000 6.49292   ? 121 SER   A N    1 
ATOM   1849 C CA   . SER   A 1 124 ? 45.94629 -17.06432 5.51952  1.000 10.36197  ? 121 SER   A CA   1 
ATOM   1850 C C    . SER   A 1 124 ? 46.69261 -17.24625 6.83299  1.000 6.71407   ? 121 SER   A C    1 
ATOM   1851 O O    . SER   A 1 124 ? 46.45292 -18.19613 7.57815  1.000 8.12359   ? 121 SER   A O    1 
ATOM   1852 C CB   . SER   A 1 124 ? 44.78345 -16.09239 5.73624  1.000 13.09464  ? 121 SER   A CB   1 
ATOM   1853 O OG   . SER   A 1 124 ? 44.00030 -15.89647 4.56958  1.000 14.85921  ? 121 SER   A OG   1 
ATOM   1854 H H    . SER   A 1 124 ? 44.62702 -18.47546 5.24194  1.000 7.87709   ? 121 SER   A H    1 
ATOM   1855 H HA   . SER   A 1 124 ? 46.55079 -16.68691 4.86147  1.000 12.51994  ? 121 SER   A HA   1 
ATOM   1856 H HB2  . SER   A 1 124 ? 44.21139 -16.44861 6.43392  1.000 15.79915  ? 121 SER   A HB2  1 
ATOM   1857 H HB3  . SER   A 1 124 ? 45.14633 -15.23551 6.01004  1.000 15.79915  ? 121 SER   A HB3  1 
ATOM   1858 H HG   . SER   A 1 124 ? 43.67224 -16.62757 4.31765  1.000 17.91663  ? 121 SER   A HG   1 
ATOM   1859 N N    . LYS   A 1 125 ? 47.60290 -16.31453 7.10580  1.000 4.77161   ? 122 LYS   A N    1 
ATOM   1860 C CA   . LYS   A 1 125 ? 48.19875 -16.18087 8.42326  1.000 5.19118   ? 122 LYS   A CA   1 
ATOM   1861 C C    . LYS   A 1 125 ? 47.23324 -15.41428 9.32697  1.000 7.27034   ? 122 LYS   A C    1 
ATOM   1862 O O    . LYS   A 1 125 ? 46.72069 -14.35070 8.95115  1.000 8.50658   ? 122 LYS   A O    1 
ATOM   1863 C CB   . LYS   A 1 125 ? 49.53422 -15.45771 8.31602  1.000 8.33642   ? 122 LYS   A CB   1 
ATOM   1864 C CG   . LYS   A 1 125 ? 50.30723 -15.39440 9.64462  1.000 17.85232  ? 122 LYS   A CG   1 
ATOM   1865 C CD   . LYS   A 1 125 ? 51.71778 -14.82933 9.48576  1.000 27.66544  ? 122 LYS   A CD   1 
ATOM   1866 C CE   . LYS   A 1 125 ? 52.58654 -15.69261 8.57611  1.000 26.11277  ? 122 LYS   A CE   1 
ATOM   1867 N NZ   . LYS   A 1 125 ? 54.00600 -15.17639 8.52463  1.000 29.46027  ? 122 LYS   A NZ   1 
ATOM   1868 H H    . LYS   A 1 125 ? 47.89377 -15.74142 6.53436  1.000 5.81152   ? 122 LYS   A H    1 
ATOM   1869 H HA   . LYS   A 1 125 ? 48.36447 -17.05213 8.81612  1.000 6.31500   ? 122 LYS   A HA   1 
ATOM   1870 H HB2  . LYS   A 1 125 ? 50.09014 -15.92189 7.67073  1.000 10.08929  ? 122 LYS   A HB2  1 
ATOM   1871 H HB3  . LYS   A 1 125 ? 49.37403 -14.54737 8.02188  1.000 10.08929  ? 122 LYS   A HB3  1 
ATOM   1872 H HG2  . LYS   A 1 125 ? 49.82494 -14.82445 10.26386 1.000 21.50836  ? 122 LYS   A HG2  1 
ATOM   1873 H HG3  . LYS   A 1 125 ? 50.38341 -16.29022 10.00878 1.000 21.50836  ? 122 LYS   A HG3  1 
ATOM   1874 H HD2  . LYS   A 1 125 ? 51.66355 -13.94193 9.09785  1.000 33.28412  ? 122 LYS   A HD2  1 
ATOM   1875 H HD3  . LYS   A 1 125 ? 52.14319 -14.78539 10.35639 1.000 33.28412  ? 122 LYS   A HD3  1 
ATOM   1876 H HE2  . LYS   A 1 125 ? 52.60333 -16.60156 8.91438  1.000 31.42091  ? 122 LYS   A HE2  1 
ATOM   1877 H HE3  . LYS   A 1 125 ? 52.22328 -15.67996 7.67679  1.000 31.42091  ? 122 LYS   A HE3  1 
ATOM   1878 H HZ1  . LYS   A 1 125 ? 54.40216 -15.29596 9.31258  1.000 35.43791  ? 122 LYS   A HZ1  1 
ATOM   1879 H HZ2  . LYS   A 1 125 ? 54.46634 -15.61325 7.90065  1.000 35.43791  ? 122 LYS   A HZ2  1 
ATOM   1880 H HZ3  . LYS   A 1 125 ? 54.00722 -14.30804 8.32955  1.000 35.43791  ? 122 LYS   A HZ3  1 
ATOM   1881 N N    . VAL   A 1 126 ? 47.00015 -15.94490 10.53022 1.000 4.38853   ? 123 VAL   A N    1 
ATOM   1882 C CA   . VAL   A 1 126 ? 46.05309 -15.34226 11.46466 1.000 3.63275   ? 123 VAL   A CA   1 
ATOM   1883 C C    . VAL   A 1 126 ? 46.59232 -15.42472 12.88152 1.000 3.80363   ? 123 VAL   A C    1 
ATOM   1884 O O    . VAL   A 1 126 ? 47.43647 -16.25963 13.20035 1.000 9.33070   ? 123 VAL   A O    1 
ATOM   1885 C CB   . VAL   A 1 126 ? 44.67600 -16.02608 11.46311 1.000 4.02320   ? 123 VAL   A CB   1 
ATOM   1886 C CG1  . VAL   A 1 126 ? 44.06670 -16.01755 10.07314 1.000 6.41883   ? 123 VAL   A CG1  1 
ATOM   1887 C CG2  . VAL   A 1 126 ? 44.80955 -17.44404 12.00472 1.000 7.01678   ? 123 VAL   A CG2  1 
ATOM   1888 H H    . VAL   A 1 126 ? 47.38128 -16.65656 10.82665 1.000 5.35182   ? 123 VAL   A H    1 
ATOM   1889 H HA   . VAL   A 1 126 ? 45.96132 -14.41316 11.20151 1.000 4.44488   ? 123 VAL   A HA   1 
ATOM   1890 H HB   . VAL   A 1 126 ? 44.07020 -15.53443 12.03948 1.000 4.91343   ? 123 VAL   A HB   1 
ATOM   1891 H HG11 . VAL   A 1 126 ? 43.16748 -16.37821 10.12028 1.000 7.78818   ? 123 VAL   A HG11 1 
ATOM   1892 H HG12 . VAL   A 1 126 ? 44.04030 -15.10494 9.74549  1.000 7.78818   ? 123 VAL   A HG12 1 
ATOM   1893 H HG13 . VAL   A 1 126 ? 44.61197 -16.56417 9.48595  1.000 7.78818   ? 123 VAL   A HG13 1 
ATOM   1894 H HG21 . VAL   A 1 126 ? 44.01629 -17.94902 11.76672 1.000 8.50572   ? 123 VAL   A HG21 1 
ATOM   1895 H HG22 . VAL   A 1 126 ? 45.59494 -17.85849 11.61448 1.000 8.50572   ? 123 VAL   A HG22 1 
ATOM   1896 H HG23 . VAL   A 1 126 ? 44.90044 -17.40624 12.96971 1.000 8.50572   ? 123 VAL   A HG23 1 
ATOM   1897 N N    . THR   A 1 127 ? 46.07866 -14.54947 13.74220 1.000 4.86399   ? 124 THR   A N    1 
ATOM   1898 C CA   . THR   A 1 127 ? 46.31061 -14.67464 15.16940 1.000 2.15950   ? 124 THR   A CA   1 
ATOM   1899 C C    . THR   A 1 127 ? 44.96781 -14.73065 15.88474 1.000 3.67748   ? 124 THR   A C    1 
ATOM   1900 O O    . THR   A 1 127 ? 43.91113 -14.41917 15.32375 1.000 3.63146   ? 124 THR   A O    1 
ATOM   1901 C CB   . THR   A 1 127 ? 47.16458 -13.54397 15.72222 1.000 5.37372   ? 124 THR   A CB   1 
ATOM   1902 O OG1  . THR   A 1 127 ? 47.63346 -13.91643 17.03618 1.000 3.90404   ? 124 THR   A OG1  1 
ATOM   1903 C CG2  . THR   A 1 127 ? 46.38548 -12.25234 15.80728 1.000 3.17588   ? 124 THR   A CG2  1 
ATOM   1904 H H    . THR   A 1 127 ? 45.59282 -13.87592 13.51881 1.000 5.92238   ? 124 THR   A H    1 
ATOM   1905 H HA   . THR   A 1 127 ? 46.78823 -15.50031 15.34563 1.000 2.67699   ? 124 THR   A HA   1 
ATOM   1906 H HB   . THR   A 1 127 ? 47.91715 -13.38703 15.13069 1.000 6.53405   ? 124 THR   A HB   1 
ATOM   1907 H HG1  . THR   A 1 127 ? 48.01971 -14.66162 17.00285 1.000 4.77043   ? 124 THR   A HG1  1 
ATOM   1908 H HG21 . THR   A 1 127 ? 46.99411 -11.50382 15.90822 1.000 3.89664   ? 124 THR   A HG21 1 
ATOM   1909 H HG22 . THR   A 1 127 ? 45.86278 -12.12640 14.99993 1.000 3.89664   ? 124 THR   A HG22 1 
ATOM   1910 H HG23 . THR   A 1 127 ? 45.78631 -12.27591 16.56974 1.000 3.89664   ? 124 THR   A HG23 1 
ATOM   1911 N N    . THR   A 1 128 ? 45.01750 -15.18809 17.12706 1.000 4.80203   ? 125 THR   A N    1 
ATOM   1912 C CA   . THR   A 1 128 ? 43.84532 -15.24664 17.98294 1.000 3.71696   ? 125 THR   A CA   1 
ATOM   1913 C C    . THR   A 1 128 ? 44.30152 -14.97568 19.41190 1.000 5.87918   ? 125 THR   A C    1 
ATOM   1914 O O    . THR   A 1 128 ? 45.49921 -14.88725 19.68677 1.000 4.09743   ? 125 THR   A O    1 
ATOM   1915 C CB   . THR   A 1 128 ? 43.17704 -16.62449 17.92329 1.000 6.73367   ? 125 THR   A CB   1 
ATOM   1916 O OG1  . THR   A 1 128 ? 44.05342 -17.55799 18.59140 1.000 1.71776   ? 125 THR   A OG1  1 
ATOM   1917 C CG2  . THR   A 1 128 ? 42.91748 -17.05810 16.48963 1.000 11.65030  ? 125 THR   A CG2  1 
ATOM   1918 H H    . THR   A 1 128 ? 45.73436 -15.47640 17.50467 1.000 5.84803   ? 125 THR   A H    1 
ATOM   1919 H HA   . THR   A 1 128 ? 43.21530 -14.57007 17.68929 1.000 4.54593   ? 125 THR   A HA   1 
ATOM   1920 H HB   . THR   A 1 128 ? 42.30975 -16.60583 18.35731 1.000 8.16599   ? 125 THR   A HB   1 
ATOM   1921 H HG1  . THR   A 1 128 ? 44.05803 -17.40678 19.41766 1.000 2.14689   ? 125 THR   A HG1  1 
ATOM   1922 H HG21 . THR   A 1 128 ? 42.39048 -17.87239 16.47956 1.000 14.06595  ? 125 THR   A HG21 1 
ATOM   1923 H HG22 . THR   A 1 128 ? 42.43340 -16.36395 16.01557 1.000 14.06595  ? 125 THR   A HG22 1 
ATOM   1924 H HG23 . THR   A 1 128 ? 43.75860 -17.22184 16.03511 1.000 14.06595  ? 125 THR   A HG23 1 
ATOM   1925 N N    . HIS   A 1 129 ? 43.35074 -14.93153 20.34451 1.000 2.68515   ? 126 HIS   A N    1 
ATOM   1926 C CA   . HIS   A 1 129 ? 43.72892 -15.02683 21.75248 1.000 4.09964   ? 126 HIS   A CA   1 
ATOM   1927 C C    . HIS   A 1 129 ? 44.49381 -16.33052 21.96259 1.000 4.61509   ? 126 HIS   A C    1 
ATOM   1928 O O    . HIS   A 1 129 ? 44.17535 -17.33261 21.31594 1.000 4.57515   ? 126 HIS   A O    1 
ATOM   1929 C CB   . HIS   A 1 129 ? 42.51473 -15.00021 22.69239 1.000 3.48106   ? 126 HIS   A CB   1 
ATOM   1930 C CG   . HIS   A 1 129 ? 42.88383 -14.76235 24.13804 1.000 3.60190   ? 126 HIS   A CG   1 
ATOM   1931 N ND1  . HIS   A 1 129 ? 43.24252 -15.78075 24.99340 1.000 7.73001   ? 126 HIS   A ND1  1 
ATOM   1932 C CD2  . HIS   A 1 129 ? 42.99385 -13.61548 24.85782 1.000 9.73937   ? 126 HIS   A CD2  1 
ATOM   1933 C CE1  . HIS   A 1 129 ? 43.56355 -15.27318 26.17098 1.000 10.81715  ? 126 HIS   A CE1  1 
ATOM   1934 N NE2  . HIS   A 1 129 ? 43.41391 -13.96170 26.11989 1.000 7.15278   ? 126 HIS   A NE2  1 
ATOM   1935 H H    . HIS   A 1 129 ? 42.50799 -14.84968 20.19390 1.000 3.30777   ? 126 HIS   A H    1 
ATOM   1936 H HA   . HIS   A 1 129 ? 44.28096 -14.26219 21.97936 1.000 5.00516   ? 126 HIS   A HA   1 
ATOM   1937 H HB2  . HIS   A 1 129 ? 41.91920 -14.28638 22.41546 1.000 4.26286   ? 126 HIS   A HB2  1 
ATOM   1938 H HB3  . HIS   A 1 129 ? 42.05719 -15.85379 22.63812 1.000 4.26286   ? 126 HIS   A HB3  1 
ATOM   1939 H HD2  . HIS   A 1 129 ? 42.81747 -12.75479 24.55285 1.000 11.77283  ? 126 HIS   A HD2  1 
ATOM   1940 H HE1  . HIS   A 1 129 ? 43.84739 -15.75845 26.91183 1.000 13.06616  ? 126 HIS   A HE1  1 
ATOM   1941 H HE2  . HIS   A 1 129 ? 43.55577 -13.41523 26.76862 1.000 8.66892   ? 126 HIS   A HE2  1 
ATOM   1942 N N    . PRO   A 1 130 ? 45.51725 -16.35372 22.83753 1.000 4.82880   ? 127 PRO   A N    1 
ATOM   1943 C CA   . PRO   A 1 130 ? 46.24739 -17.62273 23.07108 1.000 4.31554   ? 127 PRO   A CA   1 
ATOM   1944 C C    . PRO   A 1 130 ? 45.32778 -18.77790 23.44049 1.000 7.31372   ? 127 PRO   A C    1 
ATOM   1945 O O    . PRO   A 1 130 ? 45.58035 -19.92753 23.05657 1.000 10.28194  ? 127 PRO   A O    1 
ATOM   1946 C CB   . PRO   A 1 130 ? 47.20600 -17.28657 24.21854 1.000 9.25848   ? 127 PRO   A CB   1 
ATOM   1947 C CG   . PRO   A 1 130 ? 47.38988 -15.82335 24.14499 1.000 14.28464  ? 127 PRO   A CG   1 
ATOM   1948 C CD   . PRO   A 1 130 ? 46.11070 -15.21873 23.56598 1.000 8.42200   ? 127 PRO   A CD   1 
ATOM   1949 H HA   . PRO   A 1 130 ? 46.76461 -17.84665 22.28162 1.000 5.26424   ? 127 PRO   A HA   1 
ATOM   1950 H HB2  . PRO   A 1 130 ? 46.81050 -17.54475 25.06578 1.000 11.19576  ? 127 PRO   A HB2  1 
ATOM   1951 H HB3  . PRO   A 1 130 ? 48.04889 -17.74938 24.09115 1.000 11.19576  ? 127 PRO   A HB3  1 
ATOM   1952 H HG2  . PRO   A 1 130 ? 47.55178 -15.47703 25.03648 1.000 17.22715  ? 127 PRO   A HG2  1 
ATOM   1953 H HG3  . PRO   A 1 130 ? 48.14550 -15.62537 23.56988 1.000 17.22715  ? 127 PRO   A HG3  1 
ATOM   1954 H HD2  . PRO   A 1 130 ? 45.52057 -14.91224 24.27218 1.000 10.19199  ? 127 PRO   A HD2  1 
ATOM   1955 H HD3  . PRO   A 1 130 ? 46.31429 -14.48687 22.96280 1.000 10.19199  ? 127 PRO   A HD3  1 
ATOM   1956 N N    . LEU   A 1 131 ? 44.24604 -18.48825 24.16336 1.000 5.83333   ? 128 LEU   A N    1 
ATOM   1957 C CA   . LEU   A 1 131 ? 43.33301 -19.52455 24.61622 1.000 7.76542   ? 128 LEU   A CA   1 
ATOM   1958 C C    . LEU   A 1 131 ? 42.45438 -20.05254 23.49516 1.000 9.53271   ? 128 LEU   A C    1 
ATOM   1959 O O    . LEU   A 1 131 ? 41.83057 -21.09708 23.66985 1.000 11.19092  ? 128 LEU   A O    1 
ATOM   1960 C CB   . LEU   A 1 131 ? 42.43890 -18.99661 25.74172 1.000 3.86775   ? 128 LEU   A CB   1 
ATOM   1961 C CG   . LEU   A 1 131 ? 43.12743 -18.76466 27.09712 1.000 19.31057  ? 128 LEU   A CG   1 
ATOM   1962 C CD1  . LEU   A 1 131 ? 42.11708 -18.18428 28.08243 1.000 18.88428  ? 128 LEU   A CD1  1 
ATOM   1963 C CD2  . LEU   A 1 131 ? 43.74205 -20.03396 27.63387 1.000 27.61320  ? 128 LEU   A CD2  1 
ATOM   1964 H H    . LEU   A 1 131 ? 44.02087 -17.69389 24.40397 1.000 7.08558   ? 128 LEU   A H    1 
ATOM   1965 H HA   . LEU   A 1 131 ? 43.85923 -20.25831 24.97061 1.000 9.40409   ? 128 LEU   A HA   1 
ATOM   1966 H HB2  . LEU   A 1 131 ? 42.06733 -18.14633 25.45912 1.000 4.72688   ? 128 LEU   A HB2  1 
ATOM   1967 H HB3  . LEU   A 1 131 ? 41.72607 -19.63805 25.88775 1.000 4.72688   ? 128 LEU   A HB3  1 
ATOM   1968 H HG   . LEU   A 1 131 ? 43.85515 -18.13359 26.98281 1.000 23.25827  ? 128 LEU   A HG   1 
ATOM   1969 H HD11 . LEU   A 1 131 ? 42.53425 -18.10892 28.95489 1.000 22.74672  ? 128 LEU   A HD11 1 
ATOM   1970 H HD12 . LEU   A 1 131 ? 41.84009 -17.30823 27.77144 1.000 22.74672  ? 128 LEU   A HD12 1 
ATOM   1971 H HD13 . LEU   A 1 131 ? 41.34961 -18.77535 28.13269 1.000 22.74672  ? 128 LEU   A HD13 1 
ATOM   1972 H HD21 . LEU   A 1 131 ? 44.02580 -19.88485 28.54938 1.000 33.22142  ? 128 LEU   A HD21 1 
ATOM   1973 H HD22 . LEU   A 1 131 ? 43.08026 -20.74251 27.60392 1.000 33.22142  ? 128 LEU   A HD22 1 
ATOM   1974 H HD23 . LEU   A 1 131 ? 44.50598 -20.27145 27.08532 1.000 33.22142  ? 128 LEU   A HD23 1 
ATOM   1975 N N    . ALA   A 1 132 ? 42.40418 -19.37222 22.35310 1.000 3.92610   ? 129 ALA   A N    1 
ATOM   1976 C CA   . ALA   A 1 132 ? 41.62673 -19.81507 21.20950 1.000 7.72644   ? 129 ALA   A CA   1 
ATOM   1977 C C    . ALA   A 1 132 ? 42.48856 -20.43988 20.11483 1.000 6.35682   ? 129 ALA   A C    1 
ATOM   1978 O O    . ALA   A 1 132 ? 41.95434 -20.82875 19.07147 1.000 8.16275   ? 129 ALA   A O    1 
ATOM   1979 C CB   . ALA   A 1 132 ? 40.82952 -18.63239 20.64034 1.000 3.34609   ? 129 ALA   A CB   1 
ATOM   1980 H H    . ALA   A 1 132 ? 42.82349 -18.63378 22.21710 1.000 4.79691   ? 129 ALA   A H    1 
ATOM   1981 H HA   . ALA   A 1 132 ? 40.99317 -20.49015 21.49892 1.000 9.35731   ? 129 ALA   A HA   1 
ATOM   1982 H HB1  . ALA   A 1 132 ? 40.30440 -18.93984 19.88495 1.000 4.10089   ? 129 ALA   A HB1  1 
ATOM   1983 H HB2  . ALA   A 1 132 ? 40.24366 -18.28491 21.33094 1.000 4.10089   ? 129 ALA   A HB2  1 
ATOM   1984 H HB3  . ALA   A 1 132 ? 41.44868 -17.94278 20.35401 1.000 4.10089   ? 129 ALA   A HB3  1 
ATOM   1985 N N    . LYS   A 1 133 ? 43.79791 -20.56989 20.32860 1.000 3.86329   ? 130 LYS   A N    1 
ATOM   1986 C CA   . LYS   A 1 133 ? 44.67357 -21.09158 19.27868 1.000 9.05507   ? 130 LYS   A CA   1 
ATOM   1987 C C    . LYS   A 1 133 ? 44.26673 -22.50132 18.84234 1.000 13.59083  ? 130 LYS   A C    1 
ATOM   1988 O O    . LYS   A 1 133 ? 44.11488 -22.77598 17.64209 1.000 6.08919   ? 130 LYS   A O    1 
ATOM   1989 C CB   . LYS   A 1 133 ? 46.11717 -21.06917 19.76599 1.000 9.61311   ? 130 LYS   A CB   1 
ATOM   1990 C CG   . LYS   A 1 133 ? 47.11741 -21.73902 18.82083 1.000 13.06644  ? 130 LYS   A CG   1 
ATOM   1991 C CD   . LYS   A 1 133 ? 48.54251 -21.56041 19.32487 1.000 14.58017  ? 130 LYS   A CD   1 
ATOM   1992 C CE   . LYS   A 1 133 ? 49.54760 -22.11658 18.33380 1.000 19.32744  ? 130 LYS   A CE   1 
ATOM   1993 N NZ   . LYS   A 1 133 ? 50.27998 -23.27885 18.85919 1.000 17.69798  ? 130 LYS   A NZ   1 
ATOM   1994 H H    . LYS   A 1 133 ? 44.19950 -20.36659 21.06140 1.000 4.72154   ? 130 LYS   A H    1 
ATOM   1995 H HA   . LYS   A 1 133 ? 44.59979 -20.51902 18.49917 1.000 10.95167  ? 130 LYS   A HA   1 
ATOM   1996 H HB2  . LYS   A 1 133 ? 46.39166 -20.14534 19.87592 1.000 11.62132  ? 130 LYS   A HB2  1 
ATOM   1997 H HB3  . LYS   A 1 133 ? 46.16302 -21.53241 20.61700 1.000 11.62132  ? 130 LYS   A HB3  1 
ATOM   1998 H HG2  . LYS   A 1 133 ? 46.92670 -22.68860 18.76772 1.000 15.76532  ? 130 LYS   A HG2  1 
ATOM   1999 H HG3  . LYS   A 1 133 ? 47.04993 -21.33734 17.94049 1.000 15.76532  ? 130 LYS   A HG3  1 
ATOM   2000 H HD2  . LYS   A 1 133 ? 48.72492 -20.61579 19.44865 1.000 17.58179  ? 130 LYS   A HD2  1 
ATOM   2001 H HD3  . LYS   A 1 133 ? 48.64868 -22.03180 20.16596 1.000 17.58179  ? 130 LYS   A HD3  1 
ATOM   2002 H HE2  . LYS   A 1 133 ? 49.07968 -22.39485 17.53098 1.000 23.27851  ? 130 LYS   A HE2  1 
ATOM   2003 H HE3  . LYS   A 1 133 ? 50.19463 -21.42675 18.11842 1.000 23.27851  ? 130 LYS   A HE3  1 
ATOM   2004 H HZ1  . LYS   A 1 133 ? 50.85590 -23.57674 18.24953 1.000 21.32316  ? 130 LYS   A HZ1  1 
ATOM   2005 H HZ2  . LYS   A 1 133 ? 50.72875 -23.04966 19.59279 1.000 21.32316  ? 130 LYS   A HZ2  1 
ATOM   2006 H HZ3  . LYS   A 1 133 ? 49.71001 -23.93179 19.06144 1.000 21.32316  ? 130 LYS   A HZ3  1 
ATOM   2007 N N    . ASP   A 1 134 ? 44.09653 -23.41568 19.80026 1.000 8.11457   ? 131 ASP   A N    1 
ATOM   2008 C CA   . ASP   A 1 134 ? 43.80665 -24.80572 19.44159 1.000 9.48269   ? 131 ASP   A CA   1 
ATOM   2009 C C    . ASP   A 1 134 ? 42.55012 -24.90678 18.58808 1.000 13.46067  ? 131 ASP   A C    1 
ATOM   2010 O O    . ASP   A 1 134 ? 42.50098 -25.67609 17.61473 1.000 14.53660  ? 131 ASP   A O    1 
ATOM   2011 C CB   . ASP   A 1 134 ? 43.65737 -25.66085 20.69834 1.000 21.45930  ? 131 ASP   A CB   1 
ATOM   2012 C CG   . ASP   A 1 134 ? 44.98565 -25.92408 21.37968 1.000 23.44574  ? 131 ASP   A CG   1 
ATOM   2013 O OD1  . ASP   A 1 134 ? 46.02880 -25.76477 20.70701 1.000 18.28005  ? 131 ASP   A OD1  1 
ATOM   2014 O OD2  . ASP   A 1 134 ? 44.97690 -26.28538 22.57751 1.000 29.10094  ? 131 ASP   A OD2  1 
ATOM   2015 H H    . ASP   A 1 134 ? 44.14243 -23.26179 20.64514 1.000 9.82307   ? 131 ASP   A H    1 
ATOM   2016 H HA   . ASP   A 1 134 ? 44.55438 -25.15024 18.92864 1.000 11.46481  ? 131 ASP   A HA   1 
ATOM   2017 H HB2  . ASP   A 1 134 ? 43.08128 -25.20078 21.32869 1.000 25.83675  ? 131 ASP   A HB2  1 
ATOM   2018 H HB3  . ASP   A 1 134 ? 43.26826 -26.51574 20.45616 1.000 25.83675  ? 131 ASP   A HB3  1 
ATOM   2019 N N    . LYS   A 1 135 ? 41.51118 -24.15201 18.95192 1.000 12.69068  ? 132 LYS   A N    1 
ATOM   2020 C CA   . LYS   A 1 135 ? 40.26735 -24.20156 18.19153 1.000 12.06257  ? 132 LYS   A CA   1 
ATOM   2021 C C    . LYS   A 1 135 ? 40.46974 -23.68151 16.77349 1.000 14.74563  ? 132 LYS   A C    1 
ATOM   2022 O O    . LYS   A 1 135 ? 39.99485 -24.29951 15.81179 1.000 8.75578   ? 132 LYS   A O    1 
ATOM   2023 C CB   . LYS   A 1 135 ? 39.17315 -23.40516 18.90361 1.000 21.52393  ? 132 LYS   A CB   1 
ATOM   2024 C CG   . LYS   A 1 135 ? 37.84840 -23.36034 18.16056 1.000 47.55374  ? 132 LYS   A CG   1 
ATOM   2025 C CD   . LYS   A 1 135 ? 36.74992 -24.09924 18.91980 1.000 86.69506  ? 132 LYS   A CD   1 
ATOM   2026 C CE   . LYS   A 1 135 ? 35.43186 -24.03459 18.16251 1.000 87.36466  ? 132 LYS   A CE   1 
ATOM   2027 N NZ   . LYS   A 1 135 ? 34.28820 -24.45744 19.00634 1.000 87.83955  ? 132 LYS   A NZ   1 
ATOM   2028 H H    . LYS   A 1 135 ? 41.50253 -23.61368 19.62253 1.000 15.31441  ? 132 LYS   A H    1 
ATOM   2029 H HA   . LYS   A 1 135 ? 39.97401 -25.12463 18.13867 1.000 14.56067  ? 132 LYS   A HA   1 
ATOM   2030 H HB2  . LYS   A 1 135 ? 39.01038 -23.80909 19.77036 1.000 25.91430  ? 132 LYS   A HB2  1 
ATOM   2031 H HB3  . LYS   A 1 135 ? 39.47834 -22.49125 19.01554 1.000 25.91430  ? 132 LYS   A HB3  1 
ATOM   2032 H HG2  . LYS   A 1 135 ? 37.57353 -22.43659 18.05092 1.000 57.15008  ? 132 LYS   A HG2  1 
ATOM   2033 H HG3  . LYS   A 1 135 ? 37.95339 -23.78050 17.29261 1.000 57.15008  ? 132 LYS   A HG3  1 
ATOM   2034 H HD2  . LYS   A 1 135 ? 36.99911 -25.03078 19.02484 1.000 104.11965 ? 132 LYS   A HD2  1 
ATOM   2035 H HD3  . LYS   A 1 135 ? 36.62535 -23.68899 19.78991 1.000 104.11965 ? 132 LYS   A HD3  1 
ATOM   2036 H HE2  . LYS   A 1 135 ? 35.27414 -23.12244 17.87268 1.000 104.92317 ? 132 LYS   A HE2  1 
ATOM   2037 H HE3  . LYS   A 1 135 ? 35.47581 -24.62415 17.39349 1.000 104.92317 ? 132 LYS   A HE3  1 
ATOM   2038 H HZ1  . LYS   A 1 135 ? 33.53490 -24.43192 18.53308 1.000 105.49304 ? 132 LYS   A HZ1  1 
ATOM   2039 H HZ2  . LYS   A 1 135 ? 34.41700 -25.28776 19.29973 1.000 105.49304 ? 132 LYS   A HZ2  1 
ATOM   2040 H HZ3  . LYS   A 1 135 ? 34.20839 -23.91304 19.70589 1.000 105.49304 ? 132 LYS   A HZ3  1 
ATOM   2041 N N    . MET   A 1 136 ? 41.17667 -22.55254 16.63262 1.000 6.46209   ? 133 MET   A N    1 
ATOM   2042 C CA   . MET   A 1 136 ? 41.40525 -21.96273 15.31888 1.000 11.42434  ? 133 MET   A CA   1 
ATOM   2043 C C    . MET   A 1 136 ? 42.19151 -22.90584 14.41194 1.000 9.45144   ? 133 MET   A C    1 
ATOM   2044 O O    . MET   A 1 136 ? 41.98583 -22.90119 13.19448 1.000 8.33820   ? 133 MET   A O    1 
ATOM   2045 C CB   . MET   A 1 136 ? 42.14186 -20.62634 15.48197 1.000 4.78869   ? 133 MET   A CB   1 
ATOM   2046 C CG   . MET   A 1 136 ? 42.33189 -19.80687 14.19483 1.000 4.99134   ? 133 MET   A CG   1 
ATOM   2047 S SD   . MET   A 1 136 ? 40.72625 -19.17591 13.75334 1.000 5.09023   ? 133 MET   A SD   1 
ATOM   2048 C CE   . MET   A 1 136 ? 40.99687 -18.39877 12.16365 1.000 6.64962   ? 133 MET   A CE   1 
ATOM   2049 H H    . MET   A 1 136 ? 41.53133 -22.11371 17.28165 1.000 7.84009   ? 133 MET   A H    1 
ATOM   2050 H HA   . MET   A 1 136 ? 40.54996 -21.78232 14.89837 1.000 13.79479  ? 133 MET   A HA   1 
ATOM   2051 H HB2  . MET   A 1 136 ? 41.63871 -20.07553 16.10192 1.000 5.83201   ? 133 MET   A HB2  1 
ATOM   2052 H HB3  . MET   A 1 136 ? 43.02476 -20.80760 15.84048 1.000 5.83201   ? 133 MET   A HB3  1 
ATOM   2053 H HG2  . MET   A 1 136 ? 42.94097 -19.06797 14.34956 1.000 6.07519   ? 133 MET   A HG2  1 
ATOM   2054 H HG3  . MET   A 1 136 ? 42.66830 -20.37007 13.48031 1.000 6.07519   ? 133 MET   A HG3  1 
ATOM   2055 H HE1  . MET   A 1 136 ? 40.13841 -18.17628 11.77068 1.000 8.06513   ? 133 MET   A HE1  1 
ATOM   2056 H HE2  . MET   A 1 136 ? 41.52109 -17.59268 12.29136 1.000 8.06513   ? 133 MET   A HE2  1 
ATOM   2057 H HE3  . MET   A 1 136 ? 41.47435 -19.01606 11.58757 1.000 8.06513   ? 133 MET   A HE3  1 
ATOM   2058 N N    . MET   A 1 137 ? 43.09548 -23.71155 14.98094 1.000 9.59939   ? 134 MET   A N    1 
ATOM   2059 C CA   . MET   A 1 137 ? 44.05832 -24.49064 14.20704 1.000 11.20036  ? 134 MET   A CA   1 
ATOM   2060 C C    . MET   A 1 137 ? 43.60104 -25.91420 13.93592 1.000 8.39740   ? 134 MET   A C    1 
ATOM   2061 O O    . MET   A 1 137 ? 44.37115 -26.68349 13.34746 1.000 6.77049   ? 134 MET   A O    1 
ATOM   2062 C CB   . MET   A 1 137 ? 45.41681 -24.53794 14.92587 1.000 9.17344   ? 134 MET   A CB   1 
ATOM   2063 C CG   . MET   A 1 137 ? 46.15602 -23.20508 14.93359 1.000 6.37944   ? 134 MET   A CG   1 
ATOM   2064 S SD   . MET   A 1 137 ? 46.54595 -22.66486 13.24193 1.000 7.60867   ? 134 MET   A SD   1 
ATOM   2065 C CE   . MET   A 1 137 ? 47.71185 -23.96025 12.77582 1.000 12.52518  ? 134 MET   A CE   1 
ATOM   2066 H H    . MET   A 1 137 ? 43.16928 -23.82337 15.83044 1.000 11.60486  ? 134 MET   A H    1 
ATOM   2067 H HA   . MET   A 1 137 ? 44.18295 -24.03566 13.35947 1.000 13.52602  ? 134 MET   A HA   1 
ATOM   2068 H HB2  . MET   A 1 137 ? 45.27225 -24.80141 15.84814 1.000 11.09371  ? 134 MET   A HB2  1 
ATOM   2069 H HB3  . MET   A 1 137 ? 45.98270 -25.18751 14.48007 1.000 11.09371  ? 134 MET   A HB3  1 
ATOM   2070 H HG2  . MET   A 1 137 ? 45.59890 -22.52960 15.35102 1.000 7.74091   ? 134 MET   A HG2  1 
ATOM   2071 H HG3  . MET   A 1 137 ? 46.98695 -23.29984 15.42499 1.000 7.74091   ? 134 MET   A HG3  1 
ATOM   2072 H HE1  . MET   A 1 137 ? 48.07500 -23.75786 11.89943 1.000 15.11580  ? 134 MET   A HE1  1 
ATOM   2073 H HE2  . MET   A 1 137 ? 48.42668 -23.99233 13.43072 1.000 15.11580  ? 134 MET   A HE2  1 
ATOM   2074 H HE3  . MET   A 1 137 ? 47.24615 -24.81082 12.75253 1.000 15.11580  ? 134 MET   A HE3  1 
ATOM   2075 N N    . ASN   A 1 138 ? 42.38966 -26.28538 14.36774 1.000 10.76657  ? 135 ASN   A N    1 
ATOM   2076 C CA   . ASN   A 1 138 ? 41.85270 -27.61304 14.10374 1.000 6.18470   ? 135 ASN   A CA   1 
ATOM   2077 C C    . ASN   A 1 138 ? 41.79131 -27.84831 12.60453 1.000 10.01755  ? 135 ASN   A C    1 
ATOM   2078 O O    . ASN   A 1 138 ? 41.04244 -27.17777 11.87438 1.000 7.88796   ? 135 ASN   A O    1 
ATOM   2079 C CB   . ASN   A 1 138 ? 40.47536 -27.76035 14.76628 1.000 15.38932  ? 135 ASN   A CB   1 
ATOM   2080 C CG   . ASN   A 1 138 ? 39.87287 -29.13957 14.58828 1.000 20.68924  ? 135 ASN   A CG   1 
ATOM   2081 O OD1  . ASN   A 1 138 ? 40.53310 -30.07376 14.15534 1.000 27.24750  ? 135 ASN   A OD1  1 
ATOM   2082 N ND2  . ASN   A 1 138 ? 38.60182 -29.26175 14.91476 1.000 40.76183  ? 135 ASN   A ND2  1 
ATOM   2083 H H    . ASN   A 1 138 ? 41.86028 -25.77900 14.81823 1.000 13.00547  ? 135 ASN   A H    1 
ATOM   2084 H HA   . ASN   A 1 138 ? 42.42438 -28.29783 14.48471 1.000 7.50722   ? 135 ASN   A HA   1 
ATOM   2085 H HB2  . ASN   A 1 138 ? 40.56464 -27.59443 15.71781 1.000 18.55277  ? 135 ASN   A HB2  1 
ATOM   2086 H HB3  . ASN   A 1 138 ? 39.86648 -27.11587 14.37283 1.000 18.55277  ? 135 ASN   A HB3  1 
ATOM   2087 H HD21 . ASN   A 1 138 ? 38.20826 -30.02212 14.83389 1.000 48.99978  ? 135 ASN   A HD21 1 
ATOM   2088 H HD22 . ASN   A 1 138 ? 38.16601 -28.58109 15.20868 1.000 48.99978  ? 135 ASN   A HD22 1 
ATOM   2089 N N    . GLY   A 1 139 ? 42.60400 -28.78142 12.13808 1.000 7.73794   ? 136 GLY   A N    1 
ATOM   2090 C CA   . GLY   A 1 139 ? 42.67808 -29.08459 10.72258 1.000 5.94708   ? 136 GLY   A CA   1 
ATOM   2091 C C    . GLY   A 1 139 ? 43.84661 -28.46148 9.98841  1.000 11.36456  ? 136 GLY   A C    1 
ATOM   2092 O O    . GLY   A 1 139 ? 44.10985 -28.83808 8.84091  1.000 6.17700   ? 136 GLY   A O    1 
ATOM   2093 H H    A GLY   A 1 139 ? 43.12729 -29.25675 12.62781 0.550 9.37111   ? 136 GLY   A H    1 
ATOM   2094 H H    B GLY   A 1 139 ? 43.12729 -29.25675 12.62781 0.450 9.37111   ? 136 GLY   A H    1 
ATOM   2095 H HA2  . GLY   A 1 139 ? 42.74282 -30.04649 10.61553 1.000 7.22208   ? 136 GLY   A HA2  1 
ATOM   2096 H HA3  . GLY   A 1 139 ? 41.86386 -28.77355 10.29690 1.000 7.22208   ? 136 GLY   A HA3  1 
ATOM   2097 N N    . GLY   A 1 140 ? 44.54437 -27.51591 10.60331 1.000 6.16961   ? 137 GLY   A N    1 
ATOM   2098 C CA   . GLY   A 1 140 ? 45.69017 -26.91186 9.95170  1.000 7.25407   ? 137 GLY   A CA   1 
ATOM   2099 C C    . GLY   A 1 140 ? 45.33536 -26.06276 8.74591  1.000 3.38912   ? 137 GLY   A C    1 
ATOM   2100 O O    . GLY   A 1 140 ? 46.11145 -25.98913 7.79339  1.000 5.09180   ? 137 GLY   A O    1 
ATOM   2101 H H    . GLY   A 1 140 ? 44.37501 -27.21125 11.38950 1.000 7.48911   ? 137 GLY   A H    1 
ATOM   2102 H HA2  . GLY   A 1 140 ? 46.15337 -26.34712 10.59000 1.000 8.79047   ? 137 GLY   A HA2  1 
ATOM   2103 H HA3  . GLY   A 1 140 ? 46.29092 -27.61421 9.65726  1.000 8.79047   ? 137 GLY   A HA3  1 
ATOM   2104 N N    . HIS   A 1 141 ? 44.16651 -25.43363 8.74846  1.000 1.60680   ? 138 HIS   A N    1 
ATOM   2105 C CA   . HIS   A 1 141 ? 43.72404 -24.65791 7.58883  1.000 4.56251   ? 138 HIS   A CA   1 
ATOM   2106 C C    . HIS   A 1 141 ? 44.30450 -23.25158 7.53110  1.000 8.70306   ? 138 HIS   A C    1 
ATOM   2107 O O    . HIS   A 1 141 ? 44.23231 -22.60030 6.46983  1.000 6.37916   ? 138 HIS   A O    1 
ATOM   2108 C CB   . HIS   A 1 141 ? 42.19819 -24.57999 7.57938  1.000 5.71118   ? 138 HIS   A CB   1 
ATOM   2109 C CG   . HIS   A 1 141 ? 41.53065 -25.90332 7.38384  1.000 3.75436   ? 138 HIS   A CG   1 
ATOM   2110 N ND1  . HIS   A 1 141 ? 41.63576 -26.61809 6.21188  1.000 7.69459   ? 138 HIS   A ND1  1 
ATOM   2111 C CD2  . HIS   A 1 141 ? 40.71892 -26.61840 8.19595  1.000 9.23151   ? 138 HIS   A CD2  1 
ATOM   2112 C CE1  . HIS   A 1 141 ? 40.92654 -27.72559 6.31943  1.000 7.73858   ? 138 HIS   A CE1  1 
ATOM   2113 N NE2  . HIS   A 1 141 ? 40.37738 -27.75764 7.52102  1.000 12.38699  ? 138 HIS   A NE2  1 
ATOM   2114 H H    . HIS   A 1 141 ? 43.61081 -25.43798 9.40481  1.000 2.01375   ? 138 HIS   A H    1 
ATOM   2115 H HA   . HIS   A 1 141 ? 44.01960 -25.11715 6.78718  1.000 5.56060   ? 138 HIS   A HA   1 
ATOM   2116 H HB2  . HIS   A 1 141 ? 41.89874 -24.21959 8.42870  1.000 6.93900   ? 138 HIS   A HB2  1 
ATOM   2117 H HB3  . HIS   A 1 141 ? 41.91981 -23.99772 6.85525  1.000 6.93900   ? 138 HIS   A HB3  1 
ATOM   2118 H HD2  . HIS   A 1 141 ? 40.44475 -26.38014 9.05208  1.000 11.16340  ? 138 HIS   A HD2  1 
ATOM   2119 H HE1  . HIS   A 1 141 ? 40.82946 -28.37454 5.66039  1.000 9.37189   ? 138 HIS   A HE1  1 
ATOM   2120 H HE2  . HIS   A 1 141 ? 39.88502 -28.39211 7.82866  0.461 14.94997  ? 138 HIS   A HE2  1 
ATOM   2121 N N    . TYR   A 1 142 ? 44.87431 -22.77364 8.63414  1.000 3.72830   ? 139 TYR   A N    1 
ATOM   2122 C CA   . TYR   A 1 142 ? 45.55094 -21.48512 8.69941  1.000 5.28781   ? 139 TYR   A CA   1 
ATOM   2123 C C    . TYR   A 1 142 ? 46.97256 -21.67151 9.21807  1.000 1.72694   ? 139 TYR   A C    1 
ATOM   2124 O O    . TYR   A 1 142 ? 47.31934 -22.70059 9.78198  1.000 7.58757   ? 139 TYR   A O    1 
ATOM   2125 C CB   . TYR   A 1 142 ? 44.81402 -20.50300 9.63360  1.000 3.21128   ? 139 TYR   A CB   1 
ATOM   2126 C CG   . TYR   A 1 142 ? 43.32460 -20.33237 9.33428  1.000 2.33754   ? 139 TYR   A CG   1 
ATOM   2127 C CD1  . TYR   A 1 142 ? 42.88386 -19.36317 8.43705  1.000 2.49828   ? 139 TYR   A CD1  1 
ATOM   2128 C CD2  . TYR   A 1 142 ? 42.37452 -21.12245 9.95151  1.000 8.28324   ? 139 TYR   A CD2  1 
ATOM   2129 C CE1  . TYR   A 1 142 ? 41.51602 -19.21033 8.15570  1.000 8.24956   ? 139 TYR   A CE1  1 
ATOM   2130 C CE2  . TYR   A 1 142 ? 41.03597 -20.96624 9.69608  1.000 5.82590   ? 139 TYR   A CE2  1 
ATOM   2131 C CZ   . TYR   A 1 142 ? 40.60889 -20.01741 8.79681  1.000 9.15272   ? 139 TYR   A CZ   1 
ATOM   2132 O OH   . TYR   A 1 142 ? 39.27365 -19.88843 8.54735  1.000 9.96066   ? 139 TYR   A OH   1 
ATOM   2133 H H    A TYR   A 1 142 ? 44.88113 -23.19466 9.38400  0.530 4.55954   ? 139 TYR   A H    1 
ATOM   2134 H H    B TYR   A 1 142 ? 44.88113 -23.19466 9.38400  0.470 4.55954   ? 139 TYR   A H    1 
ATOM   2135 H HA   . TYR   A 1 142 ? 45.57755 -21.11179 7.80453  1.000 6.43095   ? 139 TYR   A HA   1 
ATOM   2136 H HB2  . TYR   A 1 142 ? 44.89368 -20.82583 10.54482 1.000 3.93912   ? 139 TYR   A HB2  1 
ATOM   2137 H HB3  . TYR   A 1 142 ? 45.22990 -19.63037 9.55324  1.000 3.93912   ? 139 TYR   A HB3  1 
ATOM   2138 H HD1  . TYR   A 1 142 ? 43.50310 -18.80975 8.01853  1.000 3.08352   ? 139 TYR   A HD1  1 
ATOM   2139 H HD2  . TYR   A 1 142 ? 42.64875 -21.77546 10.55424 1.000 10.02548  ? 139 TYR   A HD2  1 
ATOM   2140 H HE1  . TYR   A 1 142 ? 41.22896 -18.57149 7.54384  1.000 9.98506   ? 139 TYR   A HE1  1 
ATOM   2141 H HE2  . TYR   A 1 142 ? 40.41509 -21.50378 10.13249 1.000 7.07666   ? 139 TYR   A HE2  1 
ATOM   2142 H HH   . TYR   A 1 142 ? 39.14214 -19.26138 8.00410  1.000 12.03837  ? 139 TYR   A HH   1 
ATOM   2143 N N    . THR   A 1 143 ? 47.79032 -20.63472 9.06199  1.000 5.32768   ? 140 THR   A N    1 
ATOM   2144 C CA   . THR   A 1 143 ? 49.09927 -20.55607 9.68667  1.000 6.45104   ? 140 THR   A CA   1 
ATOM   2145 C C    . THR   A 1 143 ? 49.03820 -19.55840 10.83750 1.000 10.76333  ? 140 THR   A C    1 
ATOM   2146 O O    . THR   A 1 143 ? 48.51586 -18.44562 10.69663 1.000 7.47550   ? 140 THR   A O    1 
ATOM   2147 C CB   . THR   A 1 143 ? 50.14479 -20.16335 8.65555  1.000 12.62783  ? 140 THR   A CB   1 
ATOM   2148 O OG1  . THR   A 1 143 ? 50.18307 -21.20576 7.68282  1.000 12.77833  ? 140 THR   A OG1  1 
ATOM   2149 C CG2  . THR   A 1 143 ? 51.50845 -20.05164 9.27321  1.000 10.90887  ? 140 THR   A CG2  1 
ATOM   2150 H H    . THR   A 1 143 ? 47.59979 -19.94586 8.58368  1.000 6.47880   ? 140 THR   A H    1 
ATOM   2151 H HA   . THR   A 1 143 ? 49.35872 -21.41280 10.06030 1.000 7.82683   ? 140 THR   A HA   1 
ATOM   2152 H HB   . THR   A 1 143 ? 49.92383 -19.30338 8.26498  1.000 15.23898  ? 140 THR   A HB   1 
ATOM   2153 H HG1  . THR   A 1 143 ? 50.80688 -21.06719 7.13761  1.000 15.41958  ? 140 THR   A HG1  1 
ATOM   2154 H HG21 . THR   A 1 143 ? 52.17926 -19.94942 8.58006  1.000 13.17623  ? 140 THR   A HG21 1 
ATOM   2155 H HG22 . THR   A 1 143 ? 51.54400 -19.28140 9.86174  1.000 13.17623  ? 140 THR   A HG22 1 
ATOM   2156 H HG23 . THR   A 1 143 ? 51.70619 -20.85005 9.78736  1.000 13.17623  ? 140 THR   A HG23 1 
ATOM   2157 N N    . TYR   A 1 144 ? 49.56926 -19.95125 11.97815 1.000 9.63405   ? 141 TYR   A N    1 
ATOM   2158 C CA   . TYR   A 1 144 ? 49.36933 -19.16495 13.18890 1.000 6.44063   ? 141 TYR   A CA   1 
ATOM   2159 C C    . TYR   A 1 144 ? 50.48707 -18.15351 13.40664 1.000 4.54442   ? 141 TYR   A C    1 
ATOM   2160 O O    . TYR   A 1 144 ? 51.65608 -18.42748 13.15547 1.000 14.98836  ? 141 TYR   A O    1 
ATOM   2161 C CB   . TYR   A 1 144 ? 49.24957 -20.07412 14.41433 1.000 5.93315   ? 141 TYR   A CB   1 
ATOM   2162 C CG   . TYR   A 1 144 ? 48.63366 -19.38650 15.61415 1.000 6.41780   ? 141 TYR   A CG   1 
ATOM   2163 C CD1  . TYR   A 1 144 ? 47.26371 -19.14855 15.65728 1.000 8.94422   ? 141 TYR   A CD1  1 
ATOM   2164 C CD2  . TYR   A 1 144 ? 49.41105 -18.96857 16.68910 1.000 13.48618  ? 141 TYR   A CD2  1 
ATOM   2165 C CE1  . TYR   A 1 144 ? 46.66609 -18.53093 16.74117 1.000 7.96024   ? 141 TYR   A CE1  1 
ATOM   2166 C CE2  . TYR   A 1 144 ? 48.82188 -18.32780 17.78555 1.000 10.03317  ? 141 TYR   A CE2  1 
ATOM   2167 C CZ   . TYR   A 1 144 ? 47.45971 -18.11769 17.79314 1.000 7.73249   ? 141 TYR   A CZ   1 
ATOM   2168 O OH   . TYR   A 1 144 ? 46.87065 -17.51306 18.86250 1.000 5.72137   ? 141 TYR   A OH   1 
ATOM   2169 H H    . TYR   A 1 144 ? 50.04468 -20.66054 12.08058 1.000 11.64644  ? 141 TYR   A H    1 
ATOM   2170 H HA   . TYR   A 1 144 ? 48.54462 -18.66463 13.08671 1.000 7.81434   ? 141 TYR   A HA   1 
ATOM   2171 H HB2  . TYR   A 1 144 ? 48.69100 -20.83398 14.18739 1.000 7.20537   ? 141 TYR   A HB2  1 
ATOM   2172 H HB3  . TYR   A 1 144 ? 50.13553 -20.37743 14.66728 1.000 7.20537   ? 141 TYR   A HB3  1 
ATOM   2173 H HD1  . TYR   A 1 144 ? 46.73568 -19.41167 14.93835 1.000 10.81864  ? 141 TYR   A HD1  1 
ATOM   2174 H HD2  . TYR   A 1 144 ? 50.32926 -19.11591 16.67941 1.000 16.26900  ? 141 TYR   A HD2  1 
ATOM   2175 H HE1  . TYR   A 1 144 ? 45.74609 -18.39635 16.76114 1.000 9.63787   ? 141 TYR   A HE1  1 
ATOM   2176 H HE2  . TYR   A 1 144 ? 49.34441 -18.04671 18.50169 1.000 12.12539  ? 141 TYR   A HE2  1 
ATOM   2177 H HH   . TYR   A 1 144 ? 46.03779 -17.48872 18.75598 1.000 6.95123   ? 141 TYR   A HH   1 
ATOM   2178 N N    A SER   A 1 145 ? 50.10938 -16.98140 13.88162 0.794 8.77786   ? 142 SER   A N    1 
ATOM   2179 N N    B SER   A 1 145 ? 50.11296 -16.97469 13.88028 0.206 8.74534   ? 142 SER   A N    1 
ATOM   2180 C CA   A SER   A 1 145 ? 51.03866 -15.91375 14.17999 0.794 6.47736   ? 142 SER   A CA   1 
ATOM   2181 C CA   B SER   A 1 145 ? 51.06198 -15.91329 14.16680 0.206 6.66095   ? 142 SER   A CA   1 
ATOM   2182 C C    A SER   A 1 145 ? 50.80421 -15.48082 15.61087 0.794 8.28487   ? 142 SER   A C    1 
ATOM   2183 C C    B SER   A 1 145 ? 50.80397 -15.39944 15.57009 0.206 8.33906   ? 142 SER   A C    1 
ATOM   2184 O O    A SER   A 1 145 ? 49.67037 -15.52569 16.09991 0.794 9.17226   ? 142 SER   A O    1 
ATOM   2185 O O    B SER   A 1 145 ? 49.65053 -15.31526 16.00543 0.206 9.04927   ? 142 SER   A O    1 
ATOM   2186 C CB   A SER   A 1 145 ? 50.82955 -14.72658 13.26238 0.794 10.50007  ? 142 SER   A CB   1 
ATOM   2187 C CB   B SER   A 1 145 ? 50.93418 -14.76600 13.16830 0.206 10.46104  ? 142 SER   A CB   1 
ATOM   2188 O OG   A SER   A 1 145 ? 51.46689 -13.58986 13.80657 0.794 5.90197   ? 142 SER   A OG   1 
ATOM   2189 O OG   B SER   A 1 145 ? 49.66530 -14.15119 13.27355 0.206 9.61434   ? 142 SER   A OG   1 
ATOM   2190 H H    A SER   A 1 145 ? 49.29072 -16.77456 14.04474 0.794 10.61901  ? 142 SER   A H    1 
ATOM   2191 H H    B SER   A 1 145 ? 49.29657 -16.76201 14.04723 0.206 10.57999  ? 142 SER   A H    1 
ATOM   2192 H HA   A SER   A 1 145 ? 51.95271 -16.22062 14.07399 0.794 7.85842   ? 142 SER   A HA   1 
ATOM   2193 H HA   B SER   A 1 145 ? 51.96786 -16.25630 14.11550 0.206 8.07873   ? 142 SER   A HA   1 
ATOM   2194 H HB2  A SER   A 1 145 ? 51.21101 -14.92250 12.39232 0.794 12.68566  ? 142 SER   A HB2  1 
ATOM   2195 H HB2  B SER   A 1 145 ? 51.62139 -14.10705 13.35389 0.206 12.63883  ? 142 SER   A HB2  1 
ATOM   2196 H HB3  A SER   A 1 145 ? 49.87944 -14.55117 13.17619 0.794 12.68566  ? 142 SER   A HB3  1 
ATOM   2197 H HB3  B SER   A 1 145 ? 51.04313 -15.11493 12.26982 0.206 12.63883  ? 142 SER   A HB3  1 
ATOM   2198 H HG   A SER   A 1 145 ? 51.24007 -12.90204 13.38106 0.794 7.16795   ? 142 SER   A HG   1 
ATOM   2199 H HG   B SER   A 1 145 ? 49.58612 -13.78237 14.02408 0.206 11.62279  ? 142 SER   A HG   1 
ATOM   2200 N N    . GLU   A 1 146 ? 51.88016 -15.04946 16.26915 1.000 6.90676   ? 143 GLU   A N    1 
ATOM   2201 C CA   A GLU   A 1 146 ? 51.80746 -14.48450 17.60823 0.427 11.64671  ? 143 GLU   A CA   1 
ATOM   2202 C CA   B GLU   A 1 146 ? 51.78815 -14.47993 17.60475 0.573 11.64180  ? 143 GLU   A CA   1 
ATOM   2203 C C    . GLU   A 1 146 ? 51.92150 -12.96099 17.59269 1.000 10.53465  ? 143 GLU   A C    1 
ATOM   2204 O O    . GLU   A 1 146 ? 52.04978 -12.34653 18.65815 1.000 11.83263  ? 143 GLU   A O    1 
ATOM   2205 C CB   A GLU   A 1 146 ? 52.89559 -15.08911 18.51001 0.427 16.06405  ? 143 GLU   A CB   1 
ATOM   2206 C CB   B GLU   A 1 146 ? 52.84678 -15.10561 18.52087 0.573 16.07755  ? 143 GLU   A CB   1 
ATOM   2207 C CG   A GLU   A 1 146 ? 52.79557 -16.60078 18.71630 0.427 18.41397  ? 143 GLU   A CG   1 
ATOM   2208 C CG   B GLU   A 1 146 ? 52.61509 -16.58553 18.78580 0.573 18.19934  ? 143 GLU   A CG   1 
ATOM   2209 C CD   A GLU   A 1 146 ? 52.27514 -17.00721 20.10320 0.427 19.78450  ? 143 GLU   A CD   1 
ATOM   2210 C CD   B GLU   A 1 146 ? 53.68979 -17.22229 19.65312 0.573 17.72072  ? 143 GLU   A CD   1 
ATOM   2211 O OE1  A GLU   A 1 146 ? 52.12281 -16.13599 20.99296 0.427 27.66909  ? 143 GLU   A OE1  1 
ATOM   2212 O OE1  B GLU   A 1 146 ? 54.40808 -16.49073 20.36793 0.573 23.74747  ? 143 GLU   A OE1  1 
ATOM   2213 O OE2  A GLU   A 1 146 ? 52.01818 -18.21540 20.31044 0.427 19.31219  ? 143 GLU   A OE2  1 
ATOM   2214 O OE2  B GLU   A 1 146 ? 53.79713 -18.46204 19.62502 0.573 21.57925  ? 143 GLU   A OE2  1 
ATOM   2215 H H    A GLU   A 1 146 ? 52.67860 -15.07586 15.95072 0.794 8.37369   ? 143 GLU   A H    1 
ATOM   2216 H HA   A GLU   A 1 146 ? 50.95073 -14.71967 17.99760 0.427 14.06164  ? 143 GLU   A HA   1 
ATOM   2217 H HA   B GLU   A 1 146 ? 50.91982 -14.69600 17.97919 0.573 14.05575  ? 143 GLU   A HA   1 
ATOM   2218 H HB2  A GLU   A 1 146 ? 53.76103 -14.90630 18.11191 0.427 19.36244  ? 143 GLU   A HB2  1 
ATOM   2219 H HB2  B GLU   A 1 146 ? 53.71764 -15.01018 18.10445 0.573 19.37865  ? 143 GLU   A HB2  1 
ATOM   2220 H HB3  A GLU   A 1 146 ? 52.83745 -14.67165 19.38366 0.427 19.36244  ? 143 GLU   A HB3  1 
ATOM   2221 H HB3  B GLU   A 1 146 ? 52.83481 -14.64465 19.37426 0.573 19.37865  ? 143 GLU   A HB3  1 
ATOM   2222 H HG2  A GLU   A 1 146 ? 52.18770 -16.96602 18.05449 0.427 22.18235  ? 143 GLU   A HG2  1 
ATOM   2223 H HG2  B GLU   A 1 146 ? 51.76487 -16.69297 19.24021 0.573 21.92479  ? 143 GLU   A HG2  1 
ATOM   2224 H HG3  A GLU   A 1 146 ? 53.67762 -16.98923 18.60677 0.427 22.18235  ? 143 GLU   A HG3  1 
ATOM   2225 H HG3  B GLU   A 1 146 ? 52.60010 -17.05683 17.93813 0.573 21.92479  ? 143 GLU   A HG3  1 
ATOM   2226 N N    . ASN   A 1 147 ? 51.87525 -12.33914 16.41640 1.000 10.47370  ? 144 ASN   A N    1 
ATOM   2227 C CA   . ASN   A 1 147 ? 51.87788 -10.88536 16.34699 1.000 6.59492   ? 144 ASN   A CA   1 
ATOM   2228 C C    . ASN   A 1 147 ? 50.59539 -10.32795 16.95928 1.000 10.58376  ? 144 ASN   A C    1 
ATOM   2229 O O    . ASN   A 1 147 ? 49.52601 -10.92508 16.88031 1.000 9.67057   ? 144 ASN   A O    1 
ATOM   2230 C CB   . ASN   A 1 147 ? 52.00586 -10.41666 14.90492 1.000 8.93894   ? 144 ASN   A CB   1 
ATOM   2231 C CG   . ASN   A 1 147 ? 53.39663 -10.60116 14.37067 1.000 16.81532  ? 144 ASN   A CG   1 
ATOM   2232 O OD1  . ASN   A 1 147 ? 54.37305 -10.35432 15.06204 1.000 16.76729  ? 144 ASN   A OD1  1 
ATOM   2233 N ND2  . ASN   A 1 147 ? 53.49525 -11.05414 13.14785 1.000 23.18411  ? 144 ASN   A ND2  1 
ATOM   2234 H H    . ASN   A 1 147 ? 51.84221 -12.73396 15.65310 1.000 12.65402  ? 144 ASN   A H    1 
ATOM   2235 H HA   . ASN   A 1 147 ? 52.63693 -10.53879 16.84159 1.000 7.99949   ? 144 ASN   A HA   1 
ATOM   2236 H HB2  . ASN   A 1 147 ? 51.39785 -10.92836 14.34870 1.000 10.81231  ? 144 ASN   A HB2  1 
ATOM   2237 H HB3  . ASN   A 1 147 ? 51.78580 -9.47321  14.85609 1.000 10.81231  ? 144 ASN   A HB3  1 
ATOM   2238 H HD21 . ASN   A 1 147 ? 54.27031 -11.17705 12.79603 1.000 27.90652  ? 144 ASN   A HD21 1 
ATOM   2239 H HD22 . ASN   A 1 147 ? 52.78505 -11.22913 12.69553 1.000 27.90652  ? 144 ASN   A HD22 1 
ATOM   2240 N N    . ARG   A 1 148 ? 50.69908 -9.15342  17.55682 1.000 4.40904   ? 145 ARG   A N    1 
ATOM   2241 C CA   . ARG   A 1 148 ? 49.53369 -8.57128  18.23278 1.000 6.68480   ? 145 ARG   A CA   1 
ATOM   2242 C C    . ARG   A 1 148 ? 48.42685 -8.23091  17.22736 1.000 3.12499   ? 145 ARG   A C    1 
ATOM   2243 O O    . ARG   A 1 148 ? 47.22314 -8.34253  17.52356 1.000 3.02009   ? 145 ARG   A O    1 
ATOM   2244 C CB   . ARG   A 1 148 ? 49.98367 -7.33288  19.02092 1.000 11.52604  ? 145 ARG   A CB   1 
ATOM   2245 C CG   . ARG   A 1 148 ? 50.94861 -7.64902  20.16928 1.000 12.38960  ? 145 ARG   A CG   1 
ATOM   2246 C CD   . ARG   A 1 148 ? 51.51037 -6.41061  20.85051 1.000 20.05354  ? 145 ARG   A CD   1 
ATOM   2247 N NE   . ARG   A 1 148 ? 50.46800 -5.54002  21.39268 1.000 16.53453  ? 145 ARG   A NE   1 
ATOM   2248 C CZ   . ARG   A 1 148 ? 49.83129 -5.73463  22.54650 1.000 20.17335  ? 145 ARG   A CZ   1 
ATOM   2249 N NH1  . ARG   A 1 148 ? 50.07635 -6.79187  23.30874 1.000 21.05742  ? 145 ARG   A NH1  1 
ATOM   2250 N NH2  . ARG   A 1 148 ? 48.92104 -4.84586  22.94712 1.000 19.33138  ? 145 ARG   A NH2  1 
ATOM   2251 H H    . ARG   A 1 148 ? 51.41356 -8.67590  17.58991 1.000 5.37644   ? 145 ARG   A H    1 
ATOM   2252 H HA   . ARG   A 1 148 ? 49.15992 -9.20843  18.86145 1.000 8.10735   ? 145 ARG   A HA   1 
ATOM   2253 H HB2  . ARG   A 1 148 ? 50.43404 -6.72411  18.41472 1.000 13.91683  ? 145 ARG   A HB2  1 
ATOM   2254 H HB3  . ARG   A 1 148 ? 49.20116 -6.90394  19.40117 1.000 13.91683  ? 145 ARG   A HB3  1 
ATOM   2255 H HG2  . ARG   A 1 148 ? 50.47796 -8.16806  20.84009 1.000 14.95311  ? 145 ARG   A HG2  1 
ATOM   2256 H HG3  . ARG   A 1 148 ? 51.69583 -8.15896  19.81925 1.000 14.95311  ? 145 ARG   A HG3  1 
ATOM   2257 H HD2  . ARG   A 1 148 ? 52.08261 -6.68541  21.58395 1.000 24.14983  ? 145 ARG   A HD2  1 
ATOM   2258 H HD3  . ARG   A 1 148 ? 52.02187 -5.89897  20.20437 1.000 24.14983  ? 145 ARG   A HD3  1 
ATOM   2259 H HE   . ARG   A 1 148 ? 50.24897 -4.84853  20.93066 1.000 19.92702  ? 145 ARG   A HE   1 
ATOM   2260 H HH11 . ARG   A 1 148 ? 50.65945 -7.37391  23.06213 1.000 25.35449  ? 145 ARG   A HH11 1 
ATOM   2261 H HH12 . ARG   A 1 148 ? 49.65215 -6.89542  24.04964 1.000 25.35449  ? 145 ARG   A HH12 1 
ATOM   2262 H HH21 . ARG   A 1 148 ? 48.75073 -4.15638  22.46215 1.000 23.28324  ? 145 ARG   A HH21 1 
ATOM   2263 H HH22 . ARG   A 1 148 ? 48.50443 -4.96229  23.69041 1.000 23.28324  ? 145 ARG   A HH22 1 
ATOM   2264 N N    . VAL   A 1 149 ? 48.81942 -7.78718  16.03996 1.000 5.12929   ? 146 VAL   A N    1 
ATOM   2265 C CA   . VAL   A 1 149 ? 47.91344 -7.60540  14.91445 1.000 6.61408   ? 146 VAL   A CA   1 
ATOM   2266 C C    . VAL   A 1 149 ? 48.53204 -8.31130  13.71337 1.000 7.25000   ? 146 VAL   A C    1 
ATOM   2267 O O    . VAL   A 1 149 ? 49.73626 -8.19815  13.47642 1.000 8.64734   ? 146 VAL   A O    1 
ATOM   2268 C CB   . VAL   A 1 149 ? 47.68716 -6.11527  14.58564 1.000 5.73570   ? 146 VAL   A CB   1 
ATOM   2269 C CG1  . VAL   A 1 149 ? 46.77695 -5.98116  13.41031 1.000 7.61679   ? 146 VAL   A CG1  1 
ATOM   2270 C CG2  . VAL   A 1 149 ? 47.14780 -5.35068  15.75990 1.000 12.24300  ? 146 VAL   A CG2  1 
ATOM   2271 H H    . VAL   A 1 149 ? 49.63308 -7.57785  15.85627 1.000 6.24073   ? 146 VAL   A H    1 
ATOM   2272 H HA   . VAL   A 1 149 ? 47.05349 -8.00201  15.12443 1.000 8.02248   ? 146 VAL   A HA   1 
ATOM   2273 H HB   . VAL   A 1 149 ? 48.54734 -5.72416  14.36650 1.000 6.96842   ? 146 VAL   A HB   1 
ATOM   2274 H HG11 . VAL   A 1 149 ? 46.54552 -5.04623  13.29518 1.000 9.22574   ? 146 VAL   A HG11 1 
ATOM   2275 H HG12 . VAL   A 1 149 ? 47.23240 -6.30903  12.61913 1.000 9.22574   ? 146 VAL   A HG12 1 
ATOM   2276 H HG13 . VAL   A 1 149 ? 45.97520 -6.50307  13.57061 1.000 9.22574   ? 146 VAL   A HG13 1 
ATOM   2277 H HG21 . VAL   A 1 149 ? 47.02930 -4.42236  15.50482 1.000 14.77719  ? 146 VAL   A HG21 1 
ATOM   2278 H HG22 . VAL   A 1 149 ? 46.29564 -5.73324  16.02138 1.000 14.77719  ? 146 VAL   A HG22 1 
ATOM   2279 H HG23 . VAL   A 1 149 ? 47.77813 -5.41401  16.49446 1.000 14.77719  ? 146 VAL   A HG23 1 
ATOM   2280 N N    . GLU   A 1 150 ? 47.71913 -9.03078  12.95920 1.000 6.76310   ? 147 GLU   A N    1 
ATOM   2281 C CA   . GLU   A 1 150 ? 48.16923 -9.78829  11.80298 1.000 3.92118   ? 147 GLU   A CA   1 
ATOM   2282 C C    . GLU   A 1 150 ? 47.23619 -9.47183  10.63548 1.000 6.62684   ? 147 GLU   A C    1 
ATOM   2283 O O    . GLU   A 1 150 ? 46.01022 -9.43089  10.78031 1.000 5.61289   ? 147 GLU   A O    1 
ATOM   2284 C CB   . GLU   A 1 150 ? 48.19649 -11.29766 12.08305 1.000 10.60407  ? 147 GLU   A CB   1 
ATOM   2285 C CG   . GLU   A 1 150 ? 48.92043 -12.10743 11.00210 1.000 11.57046  ? 147 GLU   A CG   1 
ATOM   2286 C CD   . GLU   A 1 150 ? 50.38635 -11.69905 10.84834 1.000 8.41610   ? 147 GLU   A CD   1 
ATOM   2287 O OE1  . GLU   A 1 150 ? 51.19216 -11.98686 11.75759 1.000 10.56380  ? 147 GLU   A OE1  1 
ATOM   2288 O OE2  . GLU   A 1 150 ? 50.71118 -11.08547 9.82571  1.000 18.92252  ? 147 GLU   A OE2  1 
ATOM   2289 H H    . GLU   A 1 150 ? 46.87363 -9.09885  13.10101 1.000 8.20130   ? 147 GLU   A H    1 
ATOM   2290 H HA   . GLU   A 1 150 ? 49.07282 -9.53118  11.56149 1.000 4.79100   ? 147 GLU   A HA   1 
ATOM   2291 H HB2  . GLU   A 1 150 ? 48.65296 -11.45124 12.92503 1.000 12.81047  ? 147 GLU   A HB2  1 
ATOM   2292 H HB3  . GLU   A 1 150 ? 47.28399 -11.62231 12.13634 1.000 12.81047  ? 147 GLU   A HB3  1 
ATOM   2293 H HG2  . GLU   A 1 150 ? 48.89310 -13.04774 11.23868 1.000 13.97014  ? 147 GLU   A HG2  1 
ATOM   2294 H HG3  . GLU   A 1 150 ? 48.47777 -11.96657 10.15057 1.000 13.97014  ? 147 GLU   A HG3  1 
ATOM   2295 N N    . LYS   A 1 151 ? 47.82251 -9.23300  9.47568  1.000 13.88907  ? 148 LYS   A N    1 
ATOM   2296 C CA   . LYS   A 1 151 ? 47.04930 -8.94101  8.27411  1.000 13.97662  ? 148 LYS   A CA   1 
ATOM   2297 C C    . LYS   A 1 151 ? 47.64270 -9.73525  7.12433  1.000 9.89520   ? 148 LYS   A C    1 
ATOM   2298 O O    . LYS   A 1 151 ? 48.83227 -9.60682  6.83353  1.000 16.24387  ? 148 LYS   A O    1 
ATOM   2299 C CB   . LYS   A 1 151 ? 47.05095 -7.44319  7.96478  1.000 13.46018  ? 148 LYS   A CB   1 
ATOM   2300 C CG   . LYS   A 1 151 ? 46.11478 -7.06176  6.79513  1.000 18.02485  ? 148 LYS   A CG   1 
ATOM   2301 C CD   . LYS   A 1 151 ? 46.17229 -5.54311  6.49916  1.000 20.09829  ? 148 LYS   A CD   1 
ATOM   2302 C CE   . LYS   A 1 151 ? 45.31646 -5.19939  5.27743  1.000 33.40012  ? 148 LYS   A CE   1 
ATOM   2303 N NZ   . LYS   A 1 151 ? 45.66017 -6.04305  4.07888  1.000 52.61201  ? 148 LYS   A NZ   1 
ATOM   2304 H H    A LYS   A 1 151 ? 48.67391 -9.23350  9.35436  0.340 16.75247  ? 148 LYS   A H    1 
ATOM   2305 H H    B LYS   A 1 151 ? 48.67391 -9.23350  9.35436  0.660 16.75247  ? 148 LYS   A H    1 
ATOM   2306 H HA   . LYS   A 1 151 ? 46.12848 -9.21984  8.39751  1.000 16.85753  ? 148 LYS   A HA   1 
ATOM   2307 H HB2  . LYS   A 1 151 ? 46.75673 -6.95963  8.75250  1.000 16.23781  ? 148 LYS   A HB2  1 
ATOM   2308 H HB3  . LYS   A 1 151 ? 47.95156 -7.17280  7.72665  1.000 16.23781  ? 148 LYS   A HB3  1 
ATOM   2309 H HG2  . LYS   A 1 151 ? 46.38722 -7.53924  5.99595  1.000 21.71541  ? 148 LYS   A HG2  1 
ATOM   2310 H HG3  . LYS   A 1 151 ? 45.20144 -7.29378  7.02507  1.000 21.71541  ? 148 LYS   A HG3  1 
ATOM   2311 H HD2  . LYS   A 1 151 ? 45.83240 -5.05046  7.26249  1.000 24.20354  ? 148 LYS   A HD2  1 
ATOM   2312 H HD3  . LYS   A 1 151 ? 47.08867 -5.28224  6.31726  1.000 24.20354  ? 148 LYS   A HD3  1 
ATOM   2313 H HE2  . LYS   A 1 151 ? 44.38229 -5.34800  5.49222  1.000 40.16573  ? 148 LYS   A HE2  1 
ATOM   2314 H HE3  . LYS   A 1 151 ? 45.45876 -4.26931  5.04163  1.000 40.16573  ? 148 LYS   A HE3  1 
ATOM   2315 H HZ1  . LYS   A 1 151 ? 45.44224 -6.89229  4.23182  1.000 63.22000  ? 148 LYS   A HZ1  1 
ATOM   2316 H HZ2  . LYS   A 1 151 ? 45.21362 -5.75428  3.36521  1.000 63.22000  ? 148 LYS   A HZ2  1 
ATOM   2317 H HZ3  . LYS   A 1 151 ? 46.53313 -5.99432  3.91257  1.000 63.22000  ? 148 LYS   A HZ3  1 
ATOM   2318 N N    . ASP   A 1 152 ? 46.84365 -10.61163 6.53214  1.000 14.93584  ? 149 ASP   A N    1 
ATOM   2319 C CA   . ASP   A 1 152 ? 47.27981 -11.41216 5.39951  1.000 14.44125  ? 149 ASP   A CA   1 
ATOM   2320 C C    . ASP   A 1 152 ? 46.20360 -11.30317 4.33667  1.000 17.12378  ? 149 ASP   A C    1 
ATOM   2321 O O    . ASP   A 1 152 ? 45.06816 -11.73694 4.55518  1.000 17.18405  ? 149 ASP   A O    1 
ATOM   2322 C CB   . ASP   A 1 152 ? 47.52182 -12.86510 5.79364  1.000 10.09914  ? 149 ASP   A CB   1 
ATOM   2323 C CG   . ASP   A 1 152 ? 48.26088 -13.64337 4.72198  1.000 13.83068  ? 149 ASP   A CG   1 
ATOM   2324 O OD1  . ASP   A 1 152 ? 48.77638 -13.04261 3.74993  1.000 15.98291  ? 149 ASP   A OD1  1 
ATOM   2325 O OD2  . ASP   A 1 152 ? 48.31170 -14.86923 4.86895  1.000 12.09827  ? 149 ASP   A OD2  1 
ATOM   2326 H H    . ASP   A 1 152 ? 46.03183 -10.76212 6.77277  1.000 18.00860  ? 149 ASP   A H    1 
ATOM   2327 H HA   . ASP   A 1 152 ? 48.11601 -11.07070 5.04583  1.000 17.41508  ? 149 ASP   A HA   1 
ATOM   2328 H HB2  . ASP   A 1 152 ? 48.05438 -12.88909 6.60401  1.000 12.20455  ? 149 ASP   A HB2  1 
ATOM   2329 H HB3  . ASP   A 1 152 ? 46.66752 -13.29882 5.94513  1.000 12.20455  ? 149 ASP   A HB3  1 
ATOM   2330 N N    . GLY   A 1 153 ? 46.55512 -10.70641 3.21021  1.000 31.36790  ? 150 GLY   A N    1 
ATOM   2331 C CA   . GLY   A 1 153 ? 45.55989 -10.45112 2.19210  1.000 35.47980  ? 150 GLY   A CA   1 
ATOM   2332 C C    . GLY   A 1 153 ? 44.46460 -9.58625  2.78357  1.000 16.57513  ? 150 GLY   A C    1 
ATOM   2333 O O    . GLY   A 1 153 ? 44.69912 -8.49155  3.31501  1.000 20.53535  ? 150 GLY   A O    1 
ATOM   2334 H H    . GLY   A 1 153 ? 47.35058 -10.44414 3.01516  1.000 37.72706  ? 150 GLY   A H    1 
ATOM   2335 H HA2  . GLY   A 1 153 ? 45.96122 -9.98916  1.43949  1.000 42.66134  ? 150 GLY   A HA2  1 
ATOM   2336 H HA3  . GLY   A 1 153 ? 45.17598 -11.28614 1.88186  1.000 42.66134  ? 150 GLY   A HA3  1 
ATOM   2337 N N    . LEU   A 1 154 ? 43.23986 -10.08357 2.73700  1.000 13.76424  ? 151 LEU   A N    1 
ATOM   2338 C CA   . LEU   A 1 154 ? 42.09582 -9.31035  3.19660  1.000 22.18373  ? 151 LEU   A CA   1 
ATOM   2339 C C    . LEU   A 1 154 ? 41.64266 -9.73061  4.58931  1.000 22.54959  ? 151 LEU   A C    1 
ATOM   2340 O O    . LEU   A 1 154 ? 40.55846 -9.34032  5.02318  1.000 11.51496  ? 151 LEU   A O    1 
ATOM   2341 C CB   . LEU   A 1 154 ? 40.94541 -9.43196  2.19159  1.000 36.28138  ? 151 LEU   A CB   1 
ATOM   2342 C CG   . LEU   A 1 154 ? 40.35897 -10.83399 2.01842  1.000 50.72916  ? 151 LEU   A CG   1 
ATOM   2343 C CD1  . LEU   A 1 154 ? 39.17847 -11.04341 2.97149  1.000 46.00746  ? 151 LEU   A CD1  1 
ATOM   2344 C CD2  . LEU   A 1 154 ? 39.92107 -11.07057 0.57712  1.000 37.09214  ? 151 LEU   A CD2  1 
ATOM   2345 H H    . LEU   A 1 154 ? 43.04441 -10.86780 2.44308  1.000 16.60268  ? 151 LEU   A H    1 
ATOM   2346 H HA   . LEU   A 1 154 ? 42.34135 -8.37298  3.24076  1.000 26.70606  ? 151 LEU   A HA   1 
ATOM   2347 H HB2  . LEU   A 1 154 ? 40.22474 -8.85225  2.48395  1.000 43.62325  ? 151 LEU   A HB2  1 
ATOM   2348 H HB3  . LEU   A 1 154 ? 41.26974 -9.14599  1.32330  1.000 43.62325  ? 151 LEU   A HB3  1 
ATOM   2349 H HG   . LEU   A 1 154 ? 41.04648 -11.48400 2.23225  1.000 60.96058  ? 151 LEU   A HG   1 
ATOM   2350 H HD11 . LEU   A 1 154 ? 38.39302 -11.28044 2.45401  1.000 55.29454  ? 151 LEU   A HD11 1 
ATOM   2351 H HD12 . LEU   A 1 154 ? 39.39510 -11.75838 3.59020  1.000 55.29454  ? 151 LEU   A HD12 1 
ATOM   2352 H HD13 . LEU   A 1 154 ? 39.01708 -10.22097 3.45979  1.000 55.29454  ? 151 LEU   A HD13 1 
ATOM   2353 H HD21 . LEU   A 1 154 ? 39.55708 -11.96643 0.50065  1.000 44.59615  ? 151 LEU   A HD21 1 
ATOM   2354 H HD22 . LEU   A 1 154 ? 39.24395 -10.41720 0.34149  1.000 44.59615  ? 151 LEU   A HD22 1 
ATOM   2355 H HD23 . LEU   A 1 154 ? 40.69009 -10.97508 -0.00631 1.000 44.59615  ? 151 LEU   A HD23 1 
ATOM   2356 N N    . ILE   A 1 155 ? 42.45670 -10.49514 5.31006  1.000 14.06949  ? 152 ILE   A N    1 
ATOM   2357 C CA   . ILE   A 1 155 ? 42.08837 -11.02344 6.62221  1.000 8.77626   ? 152 ILE   A CA   1 
ATOM   2358 C C    . ILE   A 1 155 ? 42.93245 -10.32882 7.68460  1.000 7.53051   ? 152 ILE   A C    1 
ATOM   2359 O O    . ILE   A 1 155 ? 44.16390 -10.45478 7.70253  1.000 7.49388   ? 152 ILE   A O    1 
ATOM   2360 C CB   . ILE   A 1 155 ? 42.28622 -12.54299 6.71907  1.000 16.79540  ? 152 ILE   A CB   1 
ATOM   2361 C CG1  . ILE   A 1 155 ? 41.47229 -13.27419 5.65931  1.000 16.33441  ? 152 ILE   A CG1  1 
ATOM   2362 C CG2  . ILE   A 1 155 ? 41.91202 -13.00525 8.10378  1.000 12.99893  ? 152 ILE   A CG2  1 
ATOM   2363 C CD1  . ILE   A 1 155 ? 40.00231 -13.15667 5.84597  1.000 24.91585  ? 152 ILE   A CD1  1 
ATOM   2364 H H    . ILE   A 1 155 ? 43.24471 -10.72696 5.05531  1.000 16.96897  ? 152 ILE   A H    1 
ATOM   2365 H HA   . ILE   A 1 155 ? 41.15296 -10.81514 6.77225  1.000 10.61709  ? 152 ILE   A HA   1 
ATOM   2366 H HB   . ILE   A 1 155 ? 43.21981 -12.74796 6.55387  1.000 20.24007  ? 152 ILE   A HB   1 
ATOM   2367 H HG12 . ILE   A 1 155 ? 41.69056 -12.90547 4.78908  1.000 19.68688  ? 152 ILE   A HG12 1 
ATOM   2368 H HG13 . ILE   A 1 155 ? 41.69972 -14.21675 5.68679  1.000 19.68688  ? 152 ILE   A HG13 1 
ATOM   2369 H HG21 . ILE   A 1 155 ? 41.76330 -13.96364 8.08735  1.000 15.68430  ? 152 ILE   A HG21 1 
ATOM   2370 H HG22 . ILE   A 1 155 ? 42.63574 -12.79322 8.71383  1.000 15.68430  ? 152 ILE   A HG22 1 
ATOM   2371 H HG23 . ILE   A 1 155 ? 41.10176 -12.54948 8.38066  1.000 15.68430  ? 152 ILE   A HG23 1 
ATOM   2372 H HD11 . ILE   A 1 155 ? 39.55408 -13.65343 5.14367  1.000 29.98461  ? 152 ILE   A HD11 1 
ATOM   2373 H HD12 . ILE   A 1 155 ? 39.76390 -13.52106 6.71273  1.000 29.98461  ? 152 ILE   A HD12 1 
ATOM   2374 H HD13 . ILE   A 1 155 ? 39.75202 -12.22062 5.80047  1.000 29.98461  ? 152 ILE   A HD13 1 
ATOM   2375 N N    . LEU   A 1 156 ? 42.27000 -9.63178  8.59945  1.000 6.21574   ? 153 LEU   A N    1 
ATOM   2376 C CA   . LEU   A 1 156 ? 42.95566 -8.86438  9.63297  1.000 7.83344   ? 153 LEU   A CA   1 
ATOM   2377 C C    . LEU   A 1 156 ? 42.52690 -9.38993  10.99204 1.000 4.77450   ? 153 LEU   A C    1 
ATOM   2378 O O    . LEU   A 1 156 ? 41.32458 -9.42577  11.29222 1.000 4.44985   ? 153 LEU   A O    1 
ATOM   2379 C CB   . LEU   A 1 156 ? 42.63637 -7.37891  9.49228  1.000 8.59893   ? 153 LEU   A CB   1 
ATOM   2380 C CG   . LEU   A 1 156 ? 43.43432 -6.37461  10.32581 1.000 12.91017  ? 153 LEU   A CG   1 
ATOM   2381 C CD1  . LEU   A 1 156 ? 43.30947 -5.01799  9.67266  1.000 25.31594  ? 153 LEU   A CD1  1 
ATOM   2382 C CD2  . LEU   A 1 156 ? 42.90238 -6.34645  11.71602 1.000 23.89103  ? 153 LEU   A CD2  1 
ATOM   2383 H H    . LEU   A 1 156 ? 41.41225 -9.58720  8.64281  1.000 7.54447   ? 153 LEU   A H    1 
ATOM   2384 H HA   . LEU   A 1 156 ? 43.91555 -8.98106  9.55617  1.000 9.48571   ? 153 LEU   A HA   1 
ATOM   2385 H HB2  . LEU   A 1 156 ? 42.77470 -7.13739  8.56306  1.000 10.40430  ? 153 LEU   A HB2  1 
ATOM   2386 H HB3  . LEU   A 1 156 ? 41.70433 -7.25679  9.73159  1.000 10.40430  ? 153 LEU   A HB3  1 
ATOM   2387 H HG   . LEU   A 1 156 ? 44.37145 -6.62045  10.37326 1.000 15.57779  ? 153 LEU   A HG   1 
ATOM   2388 H HD11 . LEU   A 1 156 ? 43.78549 -4.36446  10.20858 1.000 30.46472  ? 153 LEU   A HD11 1 
ATOM   2389 H HD12 . LEU   A 1 156 ? 43.69374 -5.05927  8.78298  1.000 30.46472  ? 153 LEU   A HD12 1 
ATOM   2390 H HD13 . LEU   A 1 156 ? 42.37089 -4.77954  9.61685  1.000 30.46472  ? 153 LEU   A HD13 1 
ATOM   2391 H HD21 . LEU   A 1 156 ? 43.29573 -5.59681  12.18954 1.000 28.75482  ? 153 LEU   A HD21 1 
ATOM   2392 H HD22 . LEU   A 1 156 ? 41.93797 -6.24768  11.68319 1.000 28.75482  ? 153 LEU   A HD22 1 
ATOM   2393 H HD23 . LEU   A 1 156 ? 43.13491 -7.17693  12.16001 1.000 28.75482  ? 153 LEU   A HD23 1 
ATOM   2394 N N    . THR   A 1 157 ? 43.50000 -9.84234  11.79669 1.000 3.75722   ? 154 THR   A N    1 
ATOM   2395 C CA   . THR   A 1 157 ? 43.15447 -10.47424 13.05943 1.000 4.49001   ? 154 THR   A CA   1 
ATOM   2396 C C    . THR   A 1 157 ? 44.00056 -9.89502  14.17422 1.000 2.86481   ? 154 THR   A C    1 
ATOM   2397 O O    . THR   A 1 157 ? 45.07753 -9.33730  13.94263 1.000 5.91606   ? 154 THR   A O    1 
ATOM   2398 C CB   . THR   A 1 157 ? 43.34910 -11.98904 13.02003 1.000 2.13133   ? 154 THR   A CB   1 
ATOM   2399 O OG1  . THR   A 1 157 ? 44.66582 -12.27405 12.54691 1.000 2.50506   ? 154 THR   A OG1  1 
ATOM   2400 C CG2  . THR   A 1 157 ? 42.33223 -12.64524 12.14292 1.000 1.75844   ? 154 THR   A CG2  1 
ATOM   2401 H H    . THR   A 1 157 ? 44.34204 -9.79177  11.62930 1.000 4.59425   ? 154 THR   A H    1 
ATOM   2402 H HA   . THR   A 1 157 ? 42.22100 -10.28938 13.24751 1.000 5.47359   ? 154 THR   A HA   1 
ATOM   2403 H HB   . THR   A 1 157 ? 43.23577 -12.35676 13.91044 1.000 2.64318   ? 154 THR   A HB   1 
ATOM   2404 H HG1  . THR   A 1 157 ? 44.77803 -11.93378 11.78716 1.000 3.09166   ? 154 THR   A HG1  1 
ATOM   2405 H HG21 . THR   A 1 157 ? 42.49473 -13.60074 12.10404 1.000 2.19571   ? 154 THR   A HG21 1 
ATOM   2406 H HG22 . THR   A 1 157 ? 41.44160 -12.49146 12.49509 1.000 2.19571   ? 154 THR   A HG22 1 
ATOM   2407 H HG23 . THR   A 1 157 ? 42.38323 -12.28048 11.24557 1.000 2.19571   ? 154 THR   A HG23 1 
ATOM   2408 N N    . SER   A 1 158 ? 43.52526 -10.08930 15.39790 1.000 3.43776   ? 155 SER   A N    1 
ATOM   2409 C CA   . SER   A 1 158 ? 44.20585 -9.53117  16.55039 1.000 1.25327   ? 155 SER   A CA   1 
ATOM   2410 C C    . SER   A 1 158 ? 43.87377 -10.39219 17.75539 1.000 4.50299   ? 155 SER   A C    1 
ATOM   2411 O O    . SER   A 1 158 ? 42.95119 -11.20485 17.71518 1.000 2.19472   ? 155 SER   A O    1 
ATOM   2412 C CB   . SER   A 1 158 ? 43.77924 -8.07780  16.74362 1.000 3.19724   ? 155 SER   A CB   1 
ATOM   2413 O OG   . SER   A 1 158 ? 44.67966 -7.40565  17.57018 1.000 1.86721   ? 155 SER   A OG   1 
ATOM   2414 H H    . SER   A 1 158 ? 42.81513 -10.53801 15.58225 1.000 4.21090   ? 155 SER   A H    1 
ATOM   2415 H HA   . SER   A 1 158 ? 45.16892 -9.55394  16.43692 1.000 1.58951   ? 155 SER   A HA   1 
ATOM   2416 H HB2  . SER   A 1 158 ? 43.75401 -7.63792  15.87947 1.000 3.92227   ? 155 SER   A HB2  1 
ATOM   2417 H HB3  . SER   A 1 158 ? 42.89954 -8.05790  17.15183 1.000 3.92227   ? 155 SER   A HB3  1 
ATOM   2418 H HG   . SER   A 1 158 ? 44.70821 -7.77485  18.32415 1.000 2.32624   ? 155 SER   A HG   1 
ATOM   2419 N N    . ARG   A 1 159 ? 44.56950 -10.15020 18.86579 1.000 5.07074   ? 156 ARG   A N    1 
ATOM   2420 C CA   . ARG   A 1 159 ? 44.67640 -11.18586 19.89379 1.000 4.00733   ? 156 ARG   A CA   1 
ATOM   2421 C C    . ARG   A 1 159 ? 43.74215 -11.02093 21.08643 1.000 7.83382   ? 156 ARG   A C    1 
ATOM   2422 O O    . ARG   A 1 159 ? 43.25611 -12.02163 21.60684 1.000 4.14470   ? 156 ARG   A O    1 
ATOM   2423 C CB   . ARG   A 1 159 ? 46.11063 -11.26629 20.41691 1.000 5.93023   ? 156 ARG   A CB   1 
ATOM   2424 C CG   . ARG   A 1 159 ? 47.17896 -11.49209 19.34559 1.000 4.71565   ? 156 ARG   A CG   1 
ATOM   2425 C CD   . ARG   A 1 159 ? 48.41036 -12.25166 19.92617 1.000 4.97271   ? 156 ARG   A CD   1 
ATOM   2426 N NE   . ARG   A 1 159 ? 48.14095 -13.68516 20.04236 1.000 9.07628   ? 156 ARG   A NE   1 
ATOM   2427 C CZ   . ARG   A 1 159 ? 48.95550 -14.55603 20.61078 1.000 8.90369   ? 156 ARG   A CZ   1 
ATOM   2428 N NH1  . ARG   A 1 159 ? 50.10002 -14.17015 21.14827 1.000 17.64541  ? 156 ARG   A NH1  1 
ATOM   2429 N NH2  . ARG   A 1 159 ? 48.60282 -15.83743 20.65540 1.000 12.94886  ? 156 ARG   A NH2  1 
ATOM   2430 H H    . ARG   A 1 159 ? 44.97750 -9.41393  19.04198 1.000 6.17047   ? 156 ARG   A H    1 
ATOM   2431 H HA   . ARG   A 1 159 ? 44.44050 -12.02428 19.46682 1.000 4.89439   ? 156 ARG   A HA   1 
ATOM   2432 H HB2  . ARG   A 1 159 ? 46.32073 -10.43239 20.86565 1.000 7.20186   ? 156 ARG   A HB2  1 
ATOM   2433 H HB3  . ARG   A 1 159 ? 46.16751 -12.00404 21.04411 1.000 7.20186   ? 156 ARG   A HB3  1 
ATOM   2434 H HG2  . ARG   A 1 159 ? 46.80499 -12.02200 18.62431 1.000 5.74436   ? 156 ARG   A HG2  1 
ATOM   2435 H HG3  . ARG   A 1 159 ? 47.48062 -10.63512 19.00574 1.000 5.74436   ? 156 ARG   A HG3  1 
ATOM   2436 H HD2  . ARG   A 1 159 ? 49.17132 -12.12969 19.33713 1.000 6.05283   ? 156 ARG   A HD2  1 
ATOM   2437 H HD3  . ARG   A 1 159 ? 48.61541 -11.90592 20.80897 1.000 6.05283   ? 156 ARG   A HD3  1 
ATOM   2438 H HE   . ARG   A 1 159 ? 47.40137 -13.98112 19.71827 1.000 10.97712  ? 156 ARG   A HE   1 
ATOM   2439 H HH11 . ARG   A 1 159 ? 50.32478 -13.34021 21.13145 1.000 21.26008  ? 156 ARG   A HH11 1 
ATOM   2440 H HH12 . ARG   A 1 159 ? 50.61978 -14.74906 21.51475 1.000 21.26008  ? 156 ARG   A HH12 1 
ATOM   2441 H HH21 . ARG   A 1 159 ? 47.85335 -16.08918 20.31700 1.000 15.62421  ? 156 ARG   A HH21 1 
ATOM   2442 H HH22 . ARG   A 1 159 ? 49.12421 -16.41438 21.02266 1.000 15.62421  ? 156 ARG   A HH22 1 
ATOM   2443 N N    . GLY   A 1 160 ? 43.48788 -9.81717  21.58127 1.000 3.25797   ? 157 GLY   A N    1 
ATOM   2444 C CA   . GLY   A 1 160 ? 42.68205 -9.70330  22.78130 1.000 3.96575   ? 157 GLY   A CA   1 
ATOM   2445 C C    . GLY   A 1 160 ? 42.23619 -8.30712  23.10930 1.000 3.28784   ? 157 GLY   A C    1 
ATOM   2446 O O    . GLY   A 1 160 ? 42.48638 -7.36437  22.36871 1.000 4.82430   ? 157 GLY   A O    1 
ATOM   2447 H H    . GLY   A 1 160 ? 43.76406 -9.07413  21.24779 1.000 3.99515   ? 157 GLY   A H    1 
ATOM   2448 H HA2  . GLY   A 1 160 ? 41.88775 -10.25013 22.67659 1.000 4.84449   ? 157 GLY   A HA2  1 
ATOM   2449 H HA3  . GLY   A 1 160 ? 43.19602 -10.03392 23.53458 1.000 4.84449   ? 157 GLY   A HA3  1 
ATOM   2450 N N    . PRO   A 1 161 ? 41.56654 -8.14725  24.24525 1.000 4.90769   ? 158 PRO   A N    1 
ATOM   2451 C CA   . PRO   A 1 161 ? 41.04433 -6.81388  24.58346 1.000 2.99386   ? 158 PRO   A CA   1 
ATOM   2452 C C    . PRO   A 1 161 ? 42.11190 -5.74902  24.57880 1.000 3.08201   ? 158 PRO   A C    1 
ATOM   2453 O O    . PRO   A 1 161 ? 41.87382 -4.64275  24.07098 1.000 5.23341   ? 158 PRO   A O    1 
ATOM   2454 C CB   . PRO   A 1 161 ? 40.41745 -7.02721  25.97158 1.000 9.16941   ? 158 PRO   A CB   1 
ATOM   2455 C CG   . PRO   A 1 161 ? 40.05074 -8.49103  26.00162 1.000 4.69971   ? 158 PRO   A CG   1 
ATOM   2456 C CD   . PRO   A 1 161 ? 41.18184 -9.18107  25.22390 1.000 4.08549   ? 158 PRO   A CD   1 
ATOM   2457 H HA   . PRO   A 1 161 ? 40.34199 -6.55775  23.96538 1.000 3.67822   ? 158 PRO   A HA   1 
ATOM   2458 H HB2  . PRO   A 1 161 ? 41.06332 -6.81526  26.66355 1.000 11.08888  ? 158 PRO   A HB2  1 
ATOM   2459 H HB3  . PRO   A 1 161 ? 39.63061 -6.46853  26.06982 1.000 11.08888  ? 158 PRO   A HB3  1 
ATOM   2460 H HG2  . PRO   A 1 161 ? 40.01373 -8.80686  26.91801 1.000 5.72524   ? 158 PRO   A HG2  1 
ATOM   2461 H HG3  . PRO   A 1 161 ? 39.19402 -8.62921  25.56822 1.000 5.72524   ? 158 PRO   A HG3  1 
ATOM   2462 H HD2  . PRO   A 1 161 ? 41.92369 -9.40123  25.80878 1.000 4.98817   ? 158 PRO   A HD2  1 
ATOM   2463 H HD3  . PRO   A 1 161 ? 40.86162 -9.98116  24.77867 1.000 4.98817   ? 158 PRO   A HD3  1 
ATOM   2464 N N    . GLY   A 1 162 ? 43.29589 -6.07253  25.10614 1.000 5.11556   ? 159 GLY   A N    1 
ATOM   2465 C CA   . GLY   A 1 162 ? 44.42709 -5.18427  25.18162 1.000 6.24494   ? 159 GLY   A CA   1 
ATOM   2466 C C    . GLY   A 1 162 ? 45.07034 -4.85471  23.85175 1.000 5.83779   ? 159 GLY   A C    1 
ATOM   2467 O O    . GLY   A 1 162 ? 45.93419 -3.97951  23.82103 1.000 8.74720   ? 159 GLY   A O    1 
ATOM   2468 H H    . GLY   A 1 162 ? 43.46688 -6.84551  25.44210 1.000 6.22425   ? 159 GLY   A H    1 
ATOM   2469 H HA2  . GLY   A 1 162 ? 44.14037 -4.35031  25.58561 1.000 7.57951   ? 159 GLY   A HA2  1 
ATOM   2470 H HA3  . GLY   A 1 162 ? 45.10429 -5.59133  25.74430 1.000 7.57951   ? 159 GLY   A HA3  1 
ATOM   2471 N N    . THR   A 1 163 ? 44.68874 -5.52081  22.76298 1.000 5.13277   ? 160 THR   A N    1 
ATOM   2472 C CA   . THR   A 1 163 ? 45.15210 -5.14785  21.43527 1.000 2.91821   ? 160 THR   A CA   1 
ATOM   2473 C C    . THR   A 1 163 ? 44.08617 -4.41382  20.64256 1.000 3.72867   ? 160 THR   A C    1 
ATOM   2474 O O    . THR   A 1 163 ? 44.28466 -4.17083  19.44419 1.000 4.21245   ? 160 THR   A O    1 
ATOM   2475 C CB   . THR   A 1 163 ? 45.62687 -6.38220  20.63518 1.000 6.99911   ? 160 THR   A CB   1 
ATOM   2476 O OG1  . THR   A 1 163 ? 44.55295 -7.31057  20.37491 1.000 2.06137   ? 160 THR   A OG1  1 
ATOM   2477 C CG2  . THR   A 1 163 ? 46.74244 -7.12650  21.44193 1.000 5.80818   ? 160 THR   A CG2  1 
ATOM   2478 H H    . THR   A 1 163 ? 44.15764 -6.19716  22.77182 1.000 6.24491   ? 160 THR   A H    1 
ATOM   2479 H HA   . THR   A 1 163 ? 45.91967 -4.56501  21.54499 1.000 3.58744   ? 160 THR   A HA   1 
ATOM   2480 H HB   . THR   A 1 163 ? 45.96876 -6.07617  19.78057 1.000 8.48452   ? 160 THR   A HB   1 
ATOM   2481 H HG1  . THR   A 1 163 ? 43.96680 -6.94514  19.89692 1.000 2.55923   ? 160 THR   A HG1  1 
ATOM   2482 H HG21 . THR   A 1 163 ? 47.00919 -7.93260  20.97295 1.000 7.05540   ? 160 THR   A HG21 1 
ATOM   2483 H HG22 . THR   A 1 163 ? 47.51680 -6.55152  21.54519 1.000 7.05540   ? 160 THR   A HG22 1 
ATOM   2484 H HG23 . THR   A 1 163 ? 46.41077 -7.36870  22.32069 1.000 7.05540   ? 160 THR   A HG23 1 
ATOM   2485 N N    . SER   A 1 164 ? 42.97568 -4.03738  21.29149 1.000 2.05278   ? 161 SER   A N    1 
ATOM   2486 C CA   . SER   A 1 164 ? 41.82076 -3.50658  20.57880 1.000 3.02810   ? 161 SER   A CA   1 
ATOM   2487 C C    . SER   A 1 164 ? 42.15189 -2.20265  19.88355 1.000 2.53199   ? 161 SER   A C    1 
ATOM   2488 O O    . SER   A 1 164 ? 41.65157 -1.93706  18.78148 1.000 3.81281   ? 161 SER   A O    1 
ATOM   2489 C CB   . SER   A 1 164 ? 40.65941 -3.30123  21.54662 1.000 6.13808   ? 161 SER   A CB   1 
ATOM   2490 O OG   . SER   A 1 164 ? 40.06010 -4.54023  21.89167 1.000 6.73198   ? 161 SER   A OG   1 
ATOM   2491 H H    . SER   A 1 164 ? 42.87058 -4.08116  22.14392 1.000 2.54892   ? 161 SER   A H    1 
ATOM   2492 H HA   . SER   A 1 164 ? 41.55140 -4.15087  19.90557 1.000 3.71930   ? 161 SER   A HA   1 
ATOM   2493 H HB2  . SER   A 1 164 ? 40.99229 -2.87680  22.35282 1.000 7.45128   ? 161 SER   A HB2  1 
ATOM   2494 H HB3  . SER   A 1 164 ? 39.99371 -2.73581  21.12465 1.000 7.45128   ? 161 SER   A HB3  1 
ATOM   2495 H HG   . SER   A 1 164 ? 39.40929 -4.41099  22.40678 1.000 8.16396   ? 161 SER   A HG   1 
ATOM   2496 N N    . PHE   A 1 165 ? 42.96641 -1.35676  20.52238 1.000 1.78191   ? 162 PHE   A N    1 
ATOM   2497 C CA   . PHE   A 1 165 ? 43.30862 -0.07873  19.88762 1.000 1.02153   ? 162 PHE   A CA   1 
ATOM   2498 C C    . PHE   A 1 165 ? 44.17140 -0.29312  18.64620 1.000 2.78268   ? 162 PHE   A C    1 
ATOM   2499 O O    . PHE   A 1 165 ? 43.97535 0.36950   17.61473 1.000 8.65262   ? 162 PHE   A O    1 
ATOM   2500 C CB   . PHE   A 1 165 ? 44.04000 0.84391   20.87081 1.000 3.46412   ? 162 PHE   A CB   1 
ATOM   2501 C CG   . PHE   A 1 165 ? 43.13457 1.51260   21.89721 1.000 5.33226   ? 162 PHE   A CG   1 
ATOM   2502 C CD1  . PHE   A 1 165 ? 42.35383 2.60649   21.54003 1.000 8.57444   ? 162 PHE   A CD1  1 
ATOM   2503 C CD2  . PHE   A 1 165 ? 43.07182 1.05901   23.20369 1.000 9.06230   ? 162 PHE   A CD2  1 
ATOM   2504 C CE1  . PHE   A 1 165 ? 41.52511 3.23596   22.47604 1.000 7.88419   ? 162 PHE   A CE1  1 
ATOM   2505 C CE2  . PHE   A 1 165 ? 42.23935 1.66799   24.11550 1.000 7.94862   ? 162 PHE   A CE2  1 
ATOM   2506 C CZ   . PHE   A 1 165 ? 41.48168 2.75042   23.75629 1.000 4.36463   ? 162 PHE   A CZ   1 
ATOM   2507 H H    . PHE   A 1 165 ? 43.32117 -1.49232  21.29398 1.000 2.22388   ? 162 PHE   A H    1 
ATOM   2508 H HA   . PHE   A 1 165 ? 42.48133 0.35558   19.62714 1.000 1.31142   ? 162 PHE   A HA   1 
ATOM   2509 H HB2  . PHE   A 1 165 ? 44.69716 0.32069   21.35586 1.000 4.24253   ? 162 PHE   A HB2  1 
ATOM   2510 H HB3  . PHE   A 1 165 ? 44.48097 1.54579   20.36702 1.000 4.24253   ? 162 PHE   A HB3  1 
ATOM   2511 H HD1  . PHE   A 1 165 ? 42.38274 2.92445   20.66655 1.000 10.37491  ? 162 PHE   A HD1  1 
ATOM   2512 H HD2  . PHE   A 1 165 ? 43.59599 0.33747   23.46737 1.000 10.96034  ? 162 PHE   A HD2  1 
ATOM   2513 H HE1  . PHE   A 1 165 ? 41.01194 3.97237   22.23261 1.000 9.54661   ? 162 PHE   A HE1  1 
ATOM   2514 H HE2  . PHE   A 1 165 ? 42.19110 1.34069   24.98466 1.000 9.62393   ? 162 PHE   A HE2  1 
ATOM   2515 H HZ   . PHE   A 1 165 ? 40.93327 3.15923   24.38639 1.000 5.32315   ? 162 PHE   A HZ   1 
ATOM   2516 N N    . GLU   A 1 166 ? 45.17323 -1.16815  18.74629 1.000 3.24469   ? 163 GLU   A N    1 
ATOM   2517 C CA   . GLU   A 1 166 ? 46.01881 -1.42600  17.58961 1.000 5.31611   ? 163 GLU   A CA   1 
ATOM   2518 C C    . GLU   A 1 166 ? 45.19936 -2.06024  16.47283 1.000 4.61463   ? 163 GLU   A C    1 
ATOM   2519 O O    . GLU   A 1 166 ? 45.37639 -1.73382  15.29693 1.000 7.11122   ? 163 GLU   A O    1 
ATOM   2520 C CB   . GLU   A 1 166 ? 47.19207 -2.31748  17.99344 1.000 5.31724   ? 163 GLU   A CB   1 
ATOM   2521 C CG   . GLU   A 1 166 ? 48.11736 -1.72594  19.02411 1.000 9.27912   ? 163 GLU   A CG   1 
ATOM   2522 C CD   . GLU   A 1 166 ? 48.72802 -2.77540  19.94672 1.000 25.81270  ? 163 GLU   A CD   1 
ATOM   2523 O OE1  . GLU   A 1 166 ? 49.74472 -3.39842  19.57683 1.000 19.41201  ? 163 GLU   A OE1  1 
ATOM   2524 O OE2  . GLU   A 1 166 ? 48.16650 -2.99260  21.02830 1.000 20.54853  ? 163 GLU   A OE2  1 
ATOM   2525 H H    . GLU   A 1 166 ? 45.37660 -1.61211  19.45420 1.000 3.97922   ? 163 GLU   A H    1 
ATOM   2526 H HA   . GLU   A 1 166 ? 46.39017 -0.59350  17.25803 1.000 6.46492   ? 163 GLU   A HA   1 
ATOM   2527 H HB2  . GLU   A 1 166 ? 46.83818 -3.14280  18.36019 1.000 6.46627   ? 163 GLU   A HB2  1 
ATOM   2528 H HB3  . GLU   A 1 166 ? 47.72074 -2.50582  17.20228 1.000 6.46627   ? 163 GLU   A HB3  1 
ATOM   2529 H HG2  . GLU   A 1 166 ? 48.84236 -1.26764  18.57108 1.000 11.22053  ? 163 GLU   A HG2  1 
ATOM   2530 H HG3  . GLU   A 1 166 ? 47.61964 -1.09912  19.57207 1.000 11.22053  ? 163 GLU   A HG3  1 
ATOM   2531 N N    . PHE   A 1 167 ? 44.27494 -2.95571  16.83311 1.000 1.73996   ? 164 PHE   A N    1 
ATOM   2532 C CA   . PHE   A 1 167 ? 43.38218 -3.58978  15.86041 1.000 2.25291   ? 164 PHE   A CA   1 
ATOM   2533 C C    . PHE   A 1 167 ? 42.55585 -2.54154  15.11658 1.000 7.30280   ? 164 PHE   A C    1 
ATOM   2534 O O    . PHE   A 1 167 ? 42.52511 -2.50753  13.87788 1.000 4.83886   ? 164 PHE   A O    1 
ATOM   2535 C CB   . PHE   A 1 167 ? 42.51976 -4.58017  16.63851 1.000 4.92940   ? 164 PHE   A CB   1 
ATOM   2536 C CG   . PHE   A 1 167 ? 41.40487 -5.21958  15.86673 1.000 3.03068   ? 164 PHE   A CG   1 
ATOM   2537 C CD1  . PHE   A 1 167 ? 41.67010 -6.14107  14.87955 1.000 7.11352   ? 164 PHE   A CD1  1 
ATOM   2538 C CD2  . PHE   A 1 167 ? 40.09042 -4.99043  16.22425 1.000 6.21995   ? 164 PHE   A CD2  1 
ATOM   2539 C CE1  . PHE   A 1 167 ? 40.64589 -6.77374  14.22005 1.000 5.34587   ? 164 PHE   A CE1  1 
ATOM   2540 C CE2  . PHE   A 1 167 ? 39.05603 -5.62015  15.57432 1.000 5.93412   ? 164 PHE   A CE2  1 
ATOM   2541 C CZ   . PHE   A 1 167 ? 39.33267 -6.52077  14.55612 1.000 5.37351   ? 164 PHE   A CZ   1 
ATOM   2542 H H    . PHE   A 1 167 ? 44.14277 -3.21608  17.64202 1.000 2.17353   ? 164 PHE   A H    1 
ATOM   2543 H HA   . PHE   A 1 167 ? 43.87342 -4.07077  15.17613 1.000 2.78908   ? 164 PHE   A HA   1 
ATOM   2544 H HB2  . PHE   A 1 167 ? 43.09211 -5.29369  16.96130 1.000 6.00086   ? 164 PHE   A HB2  1 
ATOM   2545 H HB3  . PHE   A 1 167 ? 42.11918 -4.11166  17.38746 1.000 6.00086   ? 164 PHE   A HB3  1 
ATOM   2546 H HD1  . PHE   A 1 167 ? 42.55161 -6.33699  14.65717 1.000 8.62180   ? 164 PHE   A HD1  1 
ATOM   2547 H HD2  . PHE   A 1 167 ? 39.90201 -4.39944  16.91717 1.000 7.54953   ? 164 PHE   A HD2  1 
ATOM   2548 H HE1  . PHE   A 1 167 ? 40.83939 -7.37843  13.54048 1.000 6.50063   ? 164 PHE   A HE1  1 
ATOM   2549 H HE2  . PHE   A 1 167 ? 38.17548 -5.44346  15.81581 1.000 7.20653   ? 164 PHE   A HE2  1 
ATOM   2550 H HZ   . PHE   A 1 167 ? 38.64078 -6.94879  14.10558 1.000 6.53380   ? 164 PHE   A HZ   1 
ATOM   2551 N N    . ALA   A 1 168 ? 41.93603 -1.62969  15.86652 1.000 4.24414   ? 165 ALA   A N    1 
ATOM   2552 C CA   . ALA   A 1 168 ? 41.07813 -0.61944  15.25375 1.000 4.14302   ? 165 ALA   A CA   1 
ATOM   2553 C C    . ALA   A 1 168 ? 41.86816 0.33292   14.36192 1.000 3.82745   ? 165 ALA   A C    1 
ATOM   2554 O O    . ALA   A 1 168 ? 41.42274 0.68427   13.25754 1.000 4.54315   ? 165 ALA   A O    1 
ATOM   2555 C CB   . ALA   A 1 168 ? 40.34603 0.15902   16.34636 1.000 6.15102   ? 165 ALA   A CB   1 
ATOM   2556 H H    . ALA   A 1 168 ? 41.99511 -1.57504  16.72274 1.000 5.17856   ? 165 ALA   A H    1 
ATOM   2557 H HA   . ALA   A 1 168 ? 40.42287 -1.06630  14.69531 1.000 5.05721   ? 165 ALA   A HA   1 
ATOM   2558 H HB1  . ALA   A 1 168 ? 39.76717 0.81738   15.93116 1.000 7.46681   ? 165 ALA   A HB1  1 
ATOM   2559 H HB2  . ALA   A 1 168 ? 39.81779 -0.45950  16.87483 1.000 7.46681   ? 165 ALA   A HB2  1 
ATOM   2560 H HB3  . ALA   A 1 168 ? 40.99930 0.60176   16.91038 1.000 7.46681   ? 165 ALA   A HB3  1 
ATOM   2561 N N    . LEU   A 1 169 ? 43.05341 0.74812   14.81174 1.000 2.92590   ? 166 LEU   A N    1 
ATOM   2562 C CA   . LEU   A 1 169 ? 43.86573 1.64943   13.99582 1.000 2.65799   ? 166 LEU   A CA   1 
ATOM   2563 C C    . LEU   A 1 169 ? 44.37812 0.96969   12.73332 1.000 5.51457   ? 166 LEU   A C    1 
ATOM   2564 O O    . LEU   A 1 169 ? 44.60347 1.63686   11.72678 1.000 3.77330   ? 166 LEU   A O    1 
ATOM   2565 C CB   . LEU   A 1 169 ? 45.02567 2.19960   14.82153 1.000 1.39211   ? 166 LEU   A CB   1 
ATOM   2566 C CG   . LEU   A 1 169 ? 44.62860 3.29027   15.82770 1.000 10.05859  ? 166 LEU   A CG   1 
ATOM   2567 C CD1  . LEU   A 1 169 ? 45.81649 3.61811   16.73206 1.000 12.60775  ? 166 LEU   A CD1  1 
ATOM   2568 C CD2  . LEU   A 1 169 ? 44.10583 4.55324   15.11829 1.000 8.95163   ? 166 LEU   A CD2  1 
ATOM   2569 H H    . LEU   A 1 169 ? 43.40163 0.52840   15.56677 1.000 3.59667   ? 166 LEU   A H    1 
ATOM   2570 H HA   . LEU   A 1 169 ? 43.31530 2.39876   13.71934 1.000 3.27517   ? 166 LEU   A HA   1 
ATOM   2571 H HB2  . LEU   A 1 169 ? 45.42232 1.46902   15.32137 1.000 1.75612   ? 166 LEU   A HB2  1 
ATOM   2572 H HB3  . LEU   A 1 169 ? 45.68068 2.58201   14.21686 1.000 1.75612   ? 166 LEU   A HB3  1 
ATOM   2573 H HG   . LEU   A 1 169 ? 43.90215 2.96038   16.37937 1.000 12.15590  ? 166 LEU   A HG   1 
ATOM   2574 H HD11 . LEU   A 1 169 ? 45.55821 4.31886   17.35105 1.000 15.21489  ? 166 LEU   A HD11 1 
ATOM   2575 H HD12 . LEU   A 1 169 ? 46.06969 2.82041   17.22243 1.000 15.21489  ? 166 LEU   A HD12 1 
ATOM   2576 H HD13 . LEU   A 1 169 ? 46.55785 3.91827   16.18324 1.000 15.21489  ? 166 LEU   A HD13 1 
ATOM   2577 H HD21 . LEU   A 1 169 ? 44.06407 5.28068   15.75859 1.000 10.82755  ? 166 LEU   A HD21 1 
ATOM   2578 H HD22 . LEU   A 1 169 ? 44.71088 4.78290   14.39574 1.000 10.82755  ? 166 LEU   A HD22 1 
ATOM   2579 H HD23 . LEU   A 1 169 ? 43.22095 4.37311   14.76412 1.000 10.82755  ? 166 LEU   A HD23 1 
ATOM   2580 N N    . ALA   A 1 170 ? 44.58828 -0.34045  12.77239 1.000 5.63453   ? 167 ALA   A N    1 
ATOM   2581 C CA   . ALA   A 1 170 ? 44.95011 -1.06567  11.55891 1.000 7.79885   ? 167 ALA   A CA   1 
ATOM   2582 C C    . ALA   A 1 170 ? 43.80594 -1.04465  10.56336 1.000 6.46852   ? 167 ALA   A C    1 
ATOM   2583 O O    . ALA   A 1 170 ? 44.02621 -0.92456  9.35681  1.000 10.53192  ? 167 ALA   A O    1 
ATOM   2584 C CB   . ALA   A 1 170 ? 45.31899 -2.50620  11.90045 1.000 12.12779  ? 167 ALA   A CB   1 
ATOM   2585 H H    . ALA   A 1 170 ? 44.52920 -0.82845  13.47805 1.000 6.84703   ? 167 ALA   A H    1 
ATOM   2586 H HA   . ALA   A 1 170 ? 45.72419 -0.64202  11.15615 1.000 9.44420   ? 167 ALA   A HA   1 
ATOM   2587 H HB1  . ALA   A 1 170 ? 45.53825 -2.97856  11.08210 1.000 14.63893  ? 167 ALA   A HB1  1 
ATOM   2588 H HB2  . ALA   A 1 170 ? 46.08459 -2.50342  12.49605 1.000 14.63893  ? 167 ALA   A HB2  1 
ATOM   2589 H HB3  . ALA   A 1 170 ? 44.56317 -2.93112  12.33529 1.000 14.63893  ? 167 ALA   A HB3  1 
ATOM   2590 N N    . ILE   A 1 171 ? 42.56888 -1.14345  11.05129 1.000 4.86860   ? 168 ILE   A N    1 
ATOM   2591 C CA   . ILE   A 1 171 ? 41.41874 -1.00691  10.15630 1.000 5.19216   ? 168 ILE   A CA   1 
ATOM   2592 C C    . ILE   A 1 171 ? 41.39937 0.38190   9.53383  1.000 12.42236  ? 168 ILE   A C    1 
ATOM   2593 O O    . ILE   A 1 171 ? 41.22554 0.54055   8.31403  1.000 10.11418  ? 168 ILE   A O    1 
ATOM   2594 C CB   . ILE   A 1 171 ? 40.11321 -1.29140  10.91127 1.000 6.53401   ? 168 ILE   A CB   1 
ATOM   2595 C CG1  . ILE   A 1 171 ? 40.06723 -2.73898  11.38173 1.000 7.36403   ? 168 ILE   A CG1  1 
ATOM   2596 C CG2  . ILE   A 1 171 ? 38.92559 -1.03752  10.03390 1.000 6.87452   ? 168 ILE   A CG2  1 
ATOM   2597 C CD1  . ILE   A 1 171 ? 38.96474 -2.97974  12.41223 1.000 8.71315   ? 168 ILE   A CD1  1 
ATOM   2598 H H    . ILE   A 1 171 ? 42.37211 -1.28574  11.87629 1.000 5.92790   ? 168 ILE   A H    1 
ATOM   2599 H HA   . ILE   A 1 171 ? 41.50549 -1.66011  9.44447  1.000 6.31617   ? 168 ILE   A HA   1 
ATOM   2600 H HB   . ILE   A 1 171 ? 40.08849 -0.69694  11.67736 1.000 7.92640   ? 168 ILE   A HB   1 
ATOM   2601 H HG12 . ILE   A 1 171 ? 39.89956 -3.31522  10.61967 1.000 8.92242   ? 168 ILE   A HG12 1 
ATOM   2602 H HG13 . ILE   A 1 171 ? 40.91715 -2.96729  11.78966 1.000 8.92242   ? 168 ILE   A HG13 1 
ATOM   2603 H HG21 . ILE   A 1 171 ? 38.13516 -1.40708  10.45763 1.000 8.33501   ? 168 ILE   A HG21 1 
ATOM   2604 H HG22 . ILE   A 1 171 ? 38.82007 -0.08072  9.91433  1.000 8.33501   ? 168 ILE   A HG22 1 
ATOM   2605 H HG23 . ILE   A 1 171 ? 39.07055 -1.46422  9.17494  1.000 8.33501   ? 168 ILE   A HG23 1 
ATOM   2606 H HD11 . ILE   A 1 171 ? 39.08751 -3.85729  12.80687 1.000 10.54137  ? 168 ILE   A HD11 1 
ATOM   2607 H HD12 . ILE   A 1 171 ? 39.02023 -2.29734  13.09935 1.000 10.54137  ? 168 ILE   A HD12 1 
ATOM   2608 H HD13 . ILE   A 1 171 ? 38.10298 -2.93386  11.96931 1.000 10.54137  ? 168 ILE   A HD13 1 
ATOM   2609 N N    . VAL   A 1 172 ? 41.58402 1.41255   10.36448 1.000 7.32667   ? 169 VAL   A N    1 
ATOM   2610 C CA   . VAL   A 1 172 ? 41.59153 2.77264   9.83875  1.000 4.96115   ? 169 VAL   A CA   1 
ATOM   2611 C C    . VAL   A 1 172 ? 42.66571 2.91226   8.77111  1.000 12.57688  ? 169 VAL   A C    1 
ATOM   2612 O O    . VAL   A 1 172 ? 42.41260 3.43471   7.68254  1.000 11.66097  ? 169 VAL   A O    1 
ATOM   2613 C CB   . VAL   A 1 172 ? 41.77033 3.79818   10.97055 1.000 5.63042   ? 169 VAL   A CB   1 
ATOM   2614 C CG1  . VAL   A 1 172 ? 41.98274 5.19416   10.40939 1.000 9.26740   ? 169 VAL   A CG1  1 
ATOM   2615 C CG2  . VAL   A 1 172 ? 40.51817 3.73777   11.85376 1.000 5.71579   ? 169 VAL   A CG2  1 
ATOM   2616 H H    . VAL   A 1 172 ? 41.70378 1.34947   11.21376 1.000 8.87759   ? 169 VAL   A H    1 
ATOM   2617 H HA   . VAL   A 1 172 ? 40.73180 2.94797   9.42519  1.000 6.03897   ? 169 VAL   A HA   1 
ATOM   2618 H HB   . VAL   A 1 172 ? 42.55665 3.59228   11.49990 1.000 6.84209   ? 169 VAL   A HB   1 
ATOM   2619 H HG11 . VAL   A 1 172 ? 41.84936 5.84303   11.11796 1.000 11.20647  ? 169 VAL   A HG11 1 
ATOM   2620 H HG12 . VAL   A 1 172 ? 42.88695 5.26181   10.06483 1.000 11.20647  ? 169 VAL   A HG12 1 
ATOM   2621 H HG13 . VAL   A 1 172 ? 41.34434 5.34805   9.69548  1.000 11.20647  ? 169 VAL   A HG13 1 
ATOM   2622 H HG21 . VAL   A 1 172 ? 40.60837 4.38125   12.57396 1.000 6.94454   ? 169 VAL   A HG21 1 
ATOM   2623 H HG22 . VAL   A 1 172 ? 39.74075 3.95164   11.31452 1.000 6.94454   ? 169 VAL   A HG22 1 
ATOM   2624 H HG23 . VAL   A 1 172 ? 40.43181 2.84309   12.21844 1.000 6.94454   ? 169 VAL   A HG23 1 
ATOM   2625 N N    . GLU   A 1 173 ? 43.88243 2.45997   9.06888  1.000 9.57708   ? 170 GLU   A N    1 
ATOM   2626 C CA   . GLU   A 1 173 ? 44.96971 2.58305   8.10047  1.000 12.52796  ? 170 GLU   A CA   1 
ATOM   2627 C C    . GLU   A 1 173 ? 44.64269 1.83697   6.80282  1.000 15.63175  ? 170 GLU   A C    1 
ATOM   2628 O O    . GLU   A 1 173 ? 44.96203 2.30328   5.70472  1.000 13.36348  ? 170 GLU   A O    1 
ATOM   2629 C CB   . GLU   A 1 173 ? 46.27483 2.07917   8.73074  1.000 13.40803  ? 170 GLU   A CB   1 
ATOM   2630 C CG   . GLU   A 1 173 ? 47.48502 2.16800   7.82677  1.000 31.93635  ? 170 GLU   A CG   1 
ATOM   2631 C CD   . GLU   A 1 173 ? 48.76287 1.81951   8.54326  1.000 32.65933  ? 170 GLU   A CD   1 
ATOM   2632 O OE1  . GLU   A 1 173 ? 48.76188 1.85140   9.79648  1.000 36.94056  ? 170 GLU   A OE1  1 
ATOM   2633 O OE2  . GLU   A 1 173 ? 49.76126 1.51982   7.84985  1.000 42.56468  ? 170 GLU   A OE2  1 
ATOM   2634 H H    . GLU   A 1 173 ? 44.10176 2.08447   9.81083  1.000 11.57808  ? 170 GLU   A H    1 
ATOM   2635 H HA   . GLU   A 1 173 ? 45.09576 3.51641   7.86842  1.000 15.11914  ? 170 GLU   A HA   1 
ATOM   2636 H HB2  . GLU   A 1 173 ? 46.46058 2.60937   9.52150  1.000 16.17522  ? 170 GLU   A HB2  1 
ATOM   2637 H HB3  . GLU   A 1 173 ? 46.15994 1.14759   8.97539  1.000 16.17522  ? 170 GLU   A HB3  1 
ATOM   2638 H HG2  . GLU   A 1 173 ? 47.37538 1.54939   7.08772  1.000 38.40920  ? 170 GLU   A HG2  1 
ATOM   2639 H HG3  . GLU   A 1 173 ? 47.56499 3.07467   7.49143  1.000 38.40920  ? 170 GLU   A HG3  1 
ATOM   2640 N N    . ALA   A 1 174 ? 43.96785 0.69928   6.90638  1.000 8.54199   ? 171 ALA   A N    1 
ATOM   2641 C CA   . ALA   A 1 174 ? 43.61541 -0.05975  5.71447  1.000 11.63866  ? 171 ALA   A CA   1 
ATOM   2642 C C    . ALA   A 1 174 ? 42.57946 0.66724   4.87230  1.000 21.89689  ? 171 ALA   A C    1 
ATOM   2643 O O    . ALA   A 1 174 ? 42.64075 0.62530   3.64624  1.000 12.62750  ? 171 ALA   A O    1 
ATOM   2644 C CB   . ALA   A 1 174 ? 43.08189 -1.43438  6.10759  1.000 9.40859   ? 171 ALA   A CB   1 
ATOM   2645 H H    A ALA   A 1 174 ? 43.70463 0.34803   7.64593  0.530 10.33597  ? 171 ALA   A H    1 
ATOM   2646 H H    B ALA   A 1 174 ? 43.70463 0.34803   7.64593  0.470 10.33597  ? 171 ALA   A H    1 
ATOM   2647 H HA   . ALA   A 1 174 ? 44.41771 -0.17538  5.18170  1.000 14.05197  ? 171 ALA   A HA   1 
ATOM   2648 H HB1  . ALA   A 1 174 ? 42.85540 -1.92707  5.30331  1.000 11.37590  ? 171 ALA   A HB1  1 
ATOM   2649 H HB2  . ALA   A 1 174 ? 43.76686 -1.90878  6.60424  1.000 11.37590  ? 171 ALA   A HB2  1 
ATOM   2650 H HB3  . ALA   A 1 174 ? 42.29220 -1.32070  6.65927  1.000 11.37590  ? 171 ALA   A HB3  1 
ATOM   2651 N N    . LEU   A 1 175 ? 41.61742 1.32714   5.50296  1.000 10.76639  ? 172 LEU   A N    1 
ATOM   2652 C CA   . LEU   A 1 175 ? 40.51688 1.94738   4.78863  1.000 12.19288  ? 172 LEU   A CA   1 
ATOM   2653 C C    . LEU   A 1 175 ? 40.85811 3.37337   4.38345  1.000 17.56478  ? 172 LEU   A C    1 
ATOM   2654 O O    . LEU   A 1 175 ? 40.60878 3.75873   3.23581  1.000 17.13432  ? 172 LEU   A O    1 
ATOM   2655 C CB   . LEU   A 1 175 ? 39.26727 1.92093   5.66053  1.000 15.71051  ? 172 LEU   A CB   1 
ATOM   2656 C CG   . LEU   A 1 175 ? 38.29686 0.78477   5.41063  1.000 21.38568  ? 172 LEU   A CG   1 
ATOM   2657 C CD1  . LEU   A 1 175 ? 39.01974 -0.49616  5.25787  1.000 20.97816  ? 172 LEU   A CD1  1 
ATOM   2658 C CD2  . LEU   A 1 175 ? 37.27590 0.66168   6.53497  1.000 20.57387  ? 172 LEU   A CD2  1 
ATOM   2659 H H    . LEU   A 1 175 ? 41.58080 1.43004   6.35599  1.000 13.00525  ? 172 LEU   A H    1 
ATOM   2660 H HA   . LEU   A 1 175 ? 40.32672 1.44475   3.98110  1.000 14.71704  ? 172 LEU   A HA   1 
ATOM   2661 H HB2  . LEU   A 1 175 ? 39.54790 1.85839   6.58694  1.000 18.93820  ? 172 LEU   A HB2  1 
ATOM   2662 H HB3  . LEU   A 1 175 ? 38.78186 2.74821   5.51604  1.000 18.93820  ? 172 LEU   A HB3  1 
ATOM   2663 H HG   . LEU   A 1 175 ? 37.81915 0.97897   4.58906  1.000 25.74840  ? 172 LEU   A HG   1 
ATOM   2664 H HD11 . LEU   A 1 175 ? 38.38683 -1.22714  5.33532  1.000 25.25938  ? 172 LEU   A HD11 1 
ATOM   2665 H HD12 . LEU   A 1 175 ? 39.44426 -0.51717  4.38595  1.000 25.25938  ? 172 LEU   A HD12 1 
ATOM   2666 H HD13 . LEU   A 1 175 ? 39.69126 -0.56484  5.95447  1.000 25.25938  ? 172 LEU   A HD13 1 
ATOM   2667 H HD21 . LEU   A 1 175 ? 36.59964 0.01546   6.27811  1.000 24.77422  ? 172 LEU   A HD21 1 
ATOM   2668 H HD22 . LEU   A 1 175 ? 37.72755 0.36531   7.34062  1.000 24.77422  ? 172 LEU   A HD22 1 
ATOM   2669 H HD23 . LEU   A 1 175 ? 36.86569 1.52773   6.68526  1.000 24.77422  ? 172 LEU   A HD23 1 
ATOM   2670 N N    . ASN   A 1 176 ? 41.43147 4.16149   5.31197  1.000 15.03661  ? 173 ASN   A N    1 
ATOM   2671 C CA   . ASN   A 1 176 ? 41.63525 5.59202   5.10122  1.000 11.66633  ? 173 ASN   A CA   1 
ATOM   2672 C C    . ASN   A 1 176 ? 43.09335 6.00738   4.97538  1.000 18.82525  ? 173 ASN   A C    1 
ATOM   2673 O O    . ASN   A 1 176 ? 43.36980 7.19465   4.73694  1.000 21.03224  ? 173 ASN   A O    1 
ATOM   2674 C CB   . ASN   A 1 176 ? 41.01850 6.40231   6.24825  1.000 13.31700  ? 173 ASN   A CB   1 
ATOM   2675 C CG   . ASN   A 1 176 ? 39.55378 6.11565   6.44937  1.000 22.11583  ? 173 ASN   A CG   1 
ATOM   2676 O OD1  . ASN   A 1 176 ? 39.09601 5.93164   7.57329  1.000 46.90029  ? 173 ASN   A OD1  1 
ATOM   2677 N ND2  . ASN   A 1 176 ? 38.81345 6.06983   5.36212  1.000 28.69733  ? 173 ASN   A ND2  1 
ATOM   2678 H H    . ASN   A 1 176 ? 41.71031 3.88095   6.07561  1.000 18.12951  ? 173 ASN   A H    1 
ATOM   2679 H HA   . ASN   A 1 176 ? 41.18320 5.82379   4.27488  1.000 14.08518  ? 173 ASN   A HA   1 
ATOM   2680 H HB2  . ASN   A 1 176 ? 41.48163 6.18495   7.07236  1.000 16.06598  ? 173 ASN   A HB2  1 
ATOM   2681 H HB3  . ASN   A 1 176 ? 41.11414 7.34771   6.05337  1.000 16.06598  ? 173 ASN   A HB3  1 
ATOM   2682 H HD21 . ASN   A 1 176 ? 37.97067 5.90952   5.42221  1.000 34.52238  ? 173 ASN   A HD21 1 
ATOM   2683 H HD22 . ASN   A 1 176 ? 39.17250 6.20019   4.59161  1.000 34.52238  ? 173 ASN   A HD22 1 
ATOM   2684 N N    . GLY   A 1 177 ? 44.03123 5.10622   5.19921  1.000 11.39582  ? 174 GLY   A N    1 
ATOM   2685 C CA   . GLY   A 1 177 ? 45.41557 5.46751   4.98517  1.000 18.25069  ? 174 GLY   A CA   1 
ATOM   2686 C C    . GLY   A 1 177 ? 46.16337 5.78598   6.27690  1.000 26.32682  ? 174 GLY   A C    1 
ATOM   2687 O O    . GLY   A 1 177 ? 45.58083 6.08140   7.31919  1.000 14.62226  ? 174 GLY   A O    1 
ATOM   2688 H H    . GLY   A 1 177 ? 43.89363 4.30101   5.46809  1.000 13.76057  ? 174 GLY   A H    1 
ATOM   2689 H HA2  . GLY   A 1 177 ? 45.87134 4.73234   4.54620  1.000 21.98641  ? 174 GLY   A HA2  1 
ATOM   2690 H HA3  . GLY   A 1 177 ? 45.45470 6.24997   4.41323  1.000 21.98641  ? 174 GLY   A HA3  1 
ATOM   2691 N N    . LYS   A 1 178 ? 47.49663 5.76378   6.17342  1.000 15.57588  ? 175 LYS   A N    1 
ATOM   2692 C CA   . LYS   A 1 178 ? 48.37658 5.90705   7.32828  1.000 21.14360  ? 175 LYS   A CA   1 
ATOM   2693 C C    . LYS   A 1 178 ? 48.25189 7.28002   7.97733  1.000 24.71848  ? 175 LYS   A C    1 
ATOM   2694 O O    . LYS   A 1 178 ? 48.36516 7.39494   9.20523  1.000 19.97477  ? 175 LYS   A O    1 
ATOM   2695 C CB   . LYS   A 1 178 ? 49.81047 5.60978   6.86226  1.000 28.16669  ? 175 LYS   A CB   1 
ATOM   2696 C CG   . LYS   A 1 178 ? 50.89190 5.69928   7.91227  1.000 55.34875  ? 175 LYS   A CG   1 
ATOM   2697 C CD   . LYS   A 1 178 ? 51.70398 6.99716   7.74820  1.000 84.83787  ? 175 LYS   A CD   1 
ATOM   2698 C CE   . LYS   A 1 178 ? 53.04971 6.92568   8.47022  1.000 81.99037  ? 175 LYS   A CE   1 
ATOM   2699 N NZ   . LYS   A 1 178 ? 53.99034 5.99452   7.78028  1.000 80.78754  ? 175 LYS   A NZ   1 
ATOM   2700 H H    . LYS   A 1 178 ? 47.92120 5.66525   5.43205  1.000 18.77664  ? 175 LYS   A H    1 
ATOM   2701 H HA   . LYS   A 1 178 ? 48.14062 5.27110   8.02168  1.000 25.45791  ? 175 LYS   A HA   1 
ATOM   2702 H HB2  . LYS   A 1 178 ? 49.83118 4.70667   6.50890  1.000 33.88562  ? 175 LYS   A HB2  1 
ATOM   2703 H HB3  . LYS   A 1 178 ? 50.03809 6.24425   6.16474  1.000 33.88562  ? 175 LYS   A HB3  1 
ATOM   2704 H HG2  . LYS   A 1 178 ? 50.48840 5.69763   8.79437  1.000 66.50408  ? 175 LYS   A HG2  1 
ATOM   2705 H HG3  . LYS   A 1 178 ? 51.49493 4.94491   7.82189  1.000 66.50408  ? 175 LYS   A HG3  1 
ATOM   2706 H HD2  . LYS   A 1 178 ? 51.87389 7.15064   6.80561  1.000 101.89103 ? 175 LYS   A HD2  1 
ATOM   2707 H HD3  . LYS   A 1 178 ? 51.20019 7.73828   8.11946  1.000 101.89103 ? 175 LYS   A HD3  1 
ATOM   2708 H HE2  . LYS   A 1 178 ? 53.45202 7.80813   8.48817  1.000 98.47403  ? 175 LYS   A HE2  1 
ATOM   2709 H HE3  . LYS   A 1 178 ? 52.91210 6.60532   9.37539  1.000 98.47403  ? 175 LYS   A HE3  1 
ATOM   2710 H HZ1  . LYS   A 1 178 ? 54.77657 5.99181   8.19733  1.000 97.03063  ? 175 LYS   A HZ1  1 
ATOM   2711 H HZ2  . LYS   A 1 178 ? 53.65856 5.16868   7.78399  1.000 97.03063  ? 175 LYS   A HZ2  1 
ATOM   2712 H HZ3  . LYS   A 1 178 ? 54.11137 6.25338   6.93740  1.000 97.03063  ? 175 LYS   A HZ3  1 
ATOM   2713 N N    . GLU   A 1 179 ? 47.97580 8.32605   7.19912  1.000 15.24399  ? 176 GLU   A N    1 
ATOM   2714 C CA   A GLU   A 1 179 ? 47.96446 9.66219   7.78330  0.507 18.00084  ? 176 GLU   A CA   1 
ATOM   2715 C CA   B GLU   A 1 179 ? 47.96189 9.66402   7.77922  0.493 18.01719  ? 176 GLU   A CA   1 
ATOM   2716 C C    . GLU   A 1 179 ? 46.71204 9.88241   8.61812  1.000 13.57927  ? 176 GLU   A C    1 
ATOM   2717 O O    . GLU   A 1 179 ? 46.77072 10.50599  9.67617  1.000 10.62700  ? 176 GLU   A O    1 
ATOM   2718 C CB   A GLU   A 1 179 ? 48.07929 10.71538  6.68542  0.507 25.27121  ? 176 GLU   A CB   1 
ATOM   2719 C CB   B GLU   A 1 179 ? 48.04897 10.72784  6.68882  0.493 25.24775  ? 176 GLU   A CB   1 
ATOM   2720 C CG   A GLU   A 1 179 ? 49.39664 10.64480  5.92190  0.507 33.04542  ? 176 GLU   A CG   1 
ATOM   2721 C CG   B GLU   A 1 179 ? 48.16050 12.13844  7.24110  0.493 30.68066  ? 176 GLU   A CG   1 
ATOM   2722 C CD   A GLU   A 1 179 ? 49.39795 11.51398  4.68575  0.507 47.38478  ? 176 GLU   A CD   1 
ATOM   2723 C CD   B GLU   A 1 179 ? 48.16800 13.20316  6.15393  0.493 40.80501  ? 176 GLU   A CD   1 
ATOM   2724 O OE1  A GLU   A 1 179 ? 48.73462 12.57779  4.70340  0.507 54.30048  ? 176 GLU   A OE1  1 
ATOM   2725 O OE1  B GLU   A 1 179 ? 47.53822 12.98567  5.09446  0.493 42.58304  ? 176 GLU   A OE1  1 
ATOM   2726 O OE2  A GLU   A 1 179 ? 50.05310 11.12613  3.69131  0.507 45.53078  ? 176 GLU   A OE2  1 
ATOM   2727 O OE2  B GLU   A 1 179 ? 48.81218 14.25604  6.35687  0.493 36.46609  ? 176 GLU   A OE2  1 
ATOM   2728 H H    A GLU   A 1 179 ? 47.79777 8.28942   6.35855  0.507 18.37837  ? 176 GLU   A H    1 
ATOM   2729 H H    B GLU   A 1 179 ? 47.79868 8.28834   6.35840  0.493 18.37837  ? 176 GLU   A H    1 
ATOM   2730 H HA   A GLU   A 1 179 ? 48.73364 9.75902   8.36630  0.507 21.68660  ? 176 GLU   A HA   1 
ATOM   2731 H HA   B GLU   A 1 179 ? 48.74201 9.75580   8.34833  0.493 21.70621  ? 176 GLU   A HA   1 
ATOM   2732 H HB2  A GLU   A 1 179 ? 47.35829 10.58607  6.04954  0.507 30.41104  ? 176 GLU   A HB2  1 
ATOM   2733 H HB2  B GLU   A 1 179 ? 48.83351 10.55684  6.14460  0.493 30.38289  ? 176 GLU   A HB2  1 
ATOM   2734 H HB3  A GLU   A 1 179 ? 48.01362 11.59596  7.08687  0.507 30.41104  ? 176 GLU   A HB3  1 
ATOM   2735 H HB3  B GLU   A 1 179 ? 47.24939 10.68331  6.14148  0.493 30.38289  ? 176 GLU   A HB3  1 
ATOM   2736 H HG2  A GLU   A 1 179 ? 50.11486 10.94441  6.50094  0.507 39.74009  ? 176 GLU   A HG2  1 
ATOM   2737 H HG2  B GLU   A 1 179 ? 47.40329 12.31013  7.82253  0.493 36.90238  ? 176 GLU   A HG2  1 
ATOM   2738 H HG3  A GLU   A 1 179 ? 49.55381 9.72844   5.64534  0.507 39.74009  ? 176 GLU   A HG3  1 
ATOM   2739 H HG3  B GLU   A 1 179 ? 48.98763 12.21649  7.74177  0.493 36.90238  ? 176 GLU   A HG3  1 
ATOM   2740 N N    . VAL   A 1 180 ? 45.57089 9.37958   8.16470  1.000 8.21384   ? 177 VAL   A N    1 
ATOM   2741 C CA   . VAL   A 1 180 ? 44.36938 9.50451   8.97967  1.000 10.78209  ? 177 VAL   A CA   1 
ATOM   2742 C C    . VAL   A 1 180 ? 44.51316 8.70308   10.26884 1.000 9.59276   ? 177 VAL   A C    1 
ATOM   2743 O O    . VAL   A 1 180 ? 44.10915 9.15788   11.34519 1.000 8.12767   ? 177 VAL   A O    1 
ATOM   2744 C CB   . VAL   A 1 180 ? 43.13840 9.08018   8.16870  1.000 14.80381  ? 177 VAL   A CB   1 
ATOM   2745 C CG1  . VAL   A 1 180 ? 41.96384 8.90335   9.05376  1.000 11.70345  ? 177 VAL   A CG1  1 
ATOM   2746 C CG2  . VAL   A 1 180 ? 42.83627 10.16422  7.10140  1.000 12.79380  ? 177 VAL   A CG2  1 
ATOM   2747 H H    . VAL   A 1 180 ? 45.46753 8.97435   7.41323  1.000 9.94219   ? 177 VAL   A H    1 
ATOM   2748 H HA   . VAL   A 1 180 ? 44.25410 10.43516  9.22767  1.000 13.02409  ? 177 VAL   A HA   1 
ATOM   2749 H HB   . VAL   A 1 180 ? 43.31604 8.23229   7.73230  1.000 17.85016  ? 177 VAL   A HB   1 
ATOM   2750 H HG11 . VAL   A 1 180 ? 41.15890 8.89573   8.51254  1.000 14.12973  ? 177 VAL   A HG11 1 
ATOM   2751 H HG12 . VAL   A 1 180 ? 42.05059 8.06244   9.52941  1.000 14.12973  ? 177 VAL   A HG12 1 
ATOM   2752 H HG13 . VAL   A 1 180 ? 41.93080 9.63878   9.68538  1.000 14.12973  ? 177 VAL   A HG13 1 
ATOM   2753 H HG21 . VAL   A 1 180 ? 42.08597 9.87356   6.55966  1.000 15.43815  ? 177 VAL   A HG21 1 
ATOM   2754 H HG22 . VAL   A 1 180 ? 42.61802 10.99638  7.54948  1.000 15.43815  ? 177 VAL   A HG22 1 
ATOM   2755 H HG23 . VAL   A 1 180 ? 43.62026 10.28488  6.54311  1.000 15.43815  ? 177 VAL   A HG23 1 
ATOM   2756 N N    . ALA   A 1 181 ? 45.07113 7.49695   10.18442 1.000 8.50238   ? 178 ALA   A N    1 
ATOM   2757 C CA   . ALA   A 1 181 ? 45.27180 6.70861   11.38967 1.000 10.47353  ? 178 ALA   A CA   1 
ATOM   2758 C C    . ALA   A 1 181 ? 46.14321 7.46831   12.37415 1.000 11.25146  ? 178 ALA   A C    1 
ATOM   2759 O O    . ALA   A 1 181 ? 45.89294 7.45164   13.58098 1.000 9.89738   ? 178 ALA   A O    1 
ATOM   2760 C CB   . ALA   A 1 181 ? 45.90943 5.36083   11.04482 1.000 15.50010  ? 178 ALA   A CB   1 
ATOM   2761 H H    . ALA   A 1 181 ? 45.33558 7.12268   9.45669  1.000 10.28844  ? 178 ALA   A H    1 
ATOM   2762 H HA   . ALA   A 1 181 ? 44.41172 6.53018   11.80117 1.000 12.65382  ? 178 ALA   A HA   1 
ATOM   2763 H HB1  . ALA   A 1 181 ? 46.01135 4.84234   11.85826 1.000 18.68571  ? 178 ALA   A HB1  1 
ATOM   2764 H HB2  . ALA   A 1 181 ? 45.33424 4.88948   10.42201 1.000 18.68571  ? 178 ALA   A HB2  1 
ATOM   2765 H HB3  . ALA   A 1 181 ? 46.77743 5.51629   10.64071 1.000 18.68571  ? 178 ALA   A HB3  1 
ATOM   2766 N N    . ALA   A 1 182 ? 47.18371 8.13006   11.87198 1.000 11.23617  ? 179 ALA   A N    1 
ATOM   2767 C CA   . ALA   A 1 182 ? 48.08813 8.85572   12.74830 1.000 8.76345   ? 179 ALA   A CA   1 
ATOM   2768 C C    . ALA   A 1 182 ? 47.38973 10.04033  13.39109 1.000 12.56842  ? 179 ALA   A C    1 
ATOM   2769 O O    . ALA   A 1 182 ? 47.58896 10.30204  14.58285 1.000 9.18665   ? 179 ALA   A O    1 
ATOM   2770 C CB   . ALA   A 1 182 ? 49.32955 9.31853   11.98510 1.000 14.18775  ? 179 ALA   A CB   1 
ATOM   2771 H H    . ALA   A 1 182 ? 47.38370 8.17258   11.03664 1.000 13.56899  ? 179 ALA   A H    1 
ATOM   2772 H HA   . ALA   A 1 182 ? 48.38354 8.25352   13.44900 1.000 10.60172  ? 179 ALA   A HA   1 
ATOM   2773 H HB1  . ALA   A 1 182 ? 49.92571 9.77518   12.59907 1.000 17.11089  ? 179 ALA   A HB1  1 
ATOM   2774 H HB2  . ALA   A 1 182 ? 49.77442 8.54418   11.60647 1.000 17.11089  ? 179 ALA   A HB2  1 
ATOM   2775 H HB3  . ALA   A 1 182 ? 49.05772 9.92302   11.27685 1.000 17.11089  ? 179 ALA   A HB3  1 
ATOM   2776 N N    . GLN   A 1 183 ? 46.55101 10.74535  12.62584 1.000 8.06317   ? 180 GLN   A N    1 
ATOM   2777 C CA   A GLN   A 1 183 ? 45.79357 11.88158  13.14801 0.594 11.48291  ? 180 GLN   A CA   1 
ATOM   2778 C CA   B GLN   A 1 183 ? 45.83843 11.88442  13.19160 0.406 11.43690  ? 180 GLN   A CA   1 
ATOM   2779 C C    . GLN   A 1 183 ? 44.78087 11.44999  14.20165 1.000 9.14681   ? 180 GLN   A C    1 
ATOM   2780 O O    . GLN   A 1 183 ? 44.53453 12.17089  15.17144 1.000 7.54408   ? 180 GLN   A O    1 
ATOM   2781 C CB   A GLN   A 1 183 ? 45.06032 12.59472  12.00024 0.594 10.82415  ? 180 GLN   A CB   1 
ATOM   2782 C CB   B GLN   A 1 183 ? 45.20798 12.72089  12.07193 0.406 11.51812  ? 180 GLN   A CB   1 
ATOM   2783 C CG   A GLN   A 1 183 ? 45.96946 13.21776  10.94189 0.594 19.55369  ? 180 GLN   A CG   1 
ATOM   2784 C CG   B GLN   A 1 183 ? 46.23039 13.54808  11.28059 0.406 17.81814  ? 180 GLN   A CG   1 
ATOM   2785 C CD   A GLN   A 1 183 ? 45.19610 13.68379  9.71129  0.594 20.17449  ? 180 GLN   A CD   1 
ATOM   2786 C CD   B GLN   A 1 183 ? 46.98877 14.54969  12.14132 0.406 19.11495  ? 180 GLN   A CD   1 
ATOM   2787 O OE1  A GLN   A 1 183 ? 44.01497 13.34496  9.51902  0.594 15.96316  ? 180 GLN   A OE1  1 
ATOM   2788 O OE1  B GLN   A 1 183 ? 46.39675 15.34984  12.86665 0.406 18.49611  ? 180 GLN   A OE1  1 
ATOM   2789 N NE2  A GLN   A 1 183 ? 45.86088 14.47094  8.87405  0.594 24.85414  ? 180 GLN   A NE2  1 
ATOM   2790 N NE2  B GLN   A 1 183 ? 48.31148 14.50009  12.06428 0.406 18.29110  ? 180 GLN   A NE2  1 
ATOM   2791 H H    A GLN   A 1 183 ? 46.40187 10.58437  11.79431 0.594 9.76139   ? 180 GLN   A H    1 
ATOM   2792 H H    B GLN   A 1 183 ? 46.38322 10.58645  11.79747 0.406 9.76139   ? 180 GLN   A H    1 
ATOM   2793 H HA   A GLN   A 1 183 ? 46.42040 12.49803  13.55787 0.594 13.86508  ? 180 GLN   A HA   1 
ATOM   2794 H HA   B GLN   A 1 183 ? 46.47490 12.44732  13.65951 0.406 13.80986  ? 180 GLN   A HA   1 
ATOM   2795 H HB2  A GLN   A 1 183 ? 44.49136 11.94972  11.55174 0.594 13.07457  ? 180 GLN   A HB2  1 
ATOM   2796 H HB2  B GLN   A 1 183 ? 44.76103 12.12571  11.44993 0.406 13.90733  ? 180 GLN   A HB2  1 
ATOM   2797 H HB3  A GLN   A 1 183 ? 44.52096 13.30771  12.37659 0.594 13.07457  ? 180 GLN   A HB3  1 
ATOM   2798 H HB3  B GLN   A 1 183 ? 44.56665 13.33483  12.46268 0.406 13.90733  ? 180 GLN   A HB3  1 
ATOM   2799 H HG2  A GLN   A 1 183 ? 46.42018 13.98712  11.32376 0.594 23.55001  ? 180 GLN   A HG2  1 
ATOM   2800 H HG2  B GLN   A 1 183 ? 46.87892 12.94741  10.88121 0.406 21.46736  ? 180 GLN   A HG2  1 
ATOM   2801 H HG3  A GLN   A 1 183 ? 46.62177 12.55911  10.65628 0.594 23.55001  ? 180 GLN   A HG3  1 
ATOM   2802 H HG3  B GLN   A 1 183 ? 45.76556 14.04269  10.58763 0.406 21.46736  ? 180 GLN   A HG3  1 
ATOM   2803 H HE21 A GLN   A 1 183 ? 46.67604 14.68703  9.04263  0.594 29.91055  ? 180 GLN   A HE21 1 
ATOM   2804 H HE21 B GLN   A 1 183 ? 48.69097 13.92509  11.54953 0.406 22.03490  ? 180 GLN   A HE21 1 
ATOM   2805 H HE22 A GLN   A 1 183 ? 45.47636 14.76475  8.16312  0.594 29.91055  ? 180 GLN   A HE22 1 
ATOM   2806 H HE22 B GLN   A 1 183 ? 48.78994 15.04292  12.52905 0.406 22.03490  ? 180 GLN   A HE22 1 
ATOM   2807 N N    . VAL   A 1 184 ? 44.12613 10.30597  13.98938 1.000 4.10109   ? 181 VAL   A N    1 
ATOM   2808 C CA   . VAL   A 1 184 ? 43.14060 9.82337   14.95522 1.000 6.71364   ? 181 VAL   A CA   1 
ATOM   2809 C C    . VAL   A 1 184 ? 43.82343 9.32160   16.21817 1.000 6.35394   ? 181 VAL   A C    1 
ATOM   2810 O O    . VAL   A 1 184 ? 43.26220 9.40587   17.30929 1.000 2.53925   ? 181 VAL   A O    1 
ATOM   2811 C CB   . VAL   A 1 184 ? 42.28458 8.72099   14.30638 1.000 10.46646  ? 181 VAL   A CB   1 
ATOM   2812 C CG1  . VAL   A 1 184 ? 41.52813 7.94551   15.34376 1.000 8.31179   ? 181 VAL   A CG1  1 
ATOM   2813 C CG2  . VAL   A 1 184 ? 41.33736 9.34075   13.27210 1.000 15.16883  ? 181 VAL   A CG2  1 
ATOM   2814 H H    . VAL   A 1 184 ? 44.23284 9.79792   13.30374 1.000 5.00690   ? 181 VAL   A H    1 
ATOM   2815 H HA   . VAL   A 1 184 ? 42.56108 10.55931  15.20713 1.000 8.14195   ? 181 VAL   A HA   1 
ATOM   2816 H HB   . VAL   A 1 184 ? 42.86551 8.09233   13.85009 1.000 12.64534  ? 181 VAL   A HB   1 
ATOM   2817 H HG11 . VAL   A 1 184 ? 40.81559 7.45010   14.91045 1.000 10.05974  ? 181 VAL   A HG11 1 
ATOM   2818 H HG12 . VAL   A 1 184 ? 42.13625 7.33227   15.78537 1.000 10.05974  ? 181 VAL   A HG12 1 
ATOM   2819 H HG13 . VAL   A 1 184 ? 41.15475 8.56434   15.99070 1.000 10.05974  ? 181 VAL   A HG13 1 
ATOM   2820 H HG21 . VAL   A 1 184 ? 40.81406 8.63533   12.86047 1.000 18.28819  ? 181 VAL   A HG21 1 
ATOM   2821 H HG22 . VAL   A 1 184 ? 40.75021 9.97041   13.71896 1.000 18.28819  ? 181 VAL   A HG22 1 
ATOM   2822 H HG23 . VAL   A 1 184 ? 41.86255 9.79946   12.59781 1.000 18.28819  ? 181 VAL   A HG23 1 
ATOM   2823 N N    . LYS   A 1 185 ? 45.04440 8.80703   16.09098 1.000 6.08550   ? 182 LYS   A N    1 
ATOM   2824 C CA   . LYS   A 1 185 ? 45.73901 8.20752   17.22522 1.000 3.60170   ? 182 LYS   A CA   1 
ATOM   2825 C C    . LYS   A 1 185 ? 46.18786 9.25009   18.23887 1.000 9.17514   ? 182 LYS   A C    1 
ATOM   2826 O O    . LYS   A 1 185 ? 46.11568 9.02293   19.45419 1.000 7.30570   ? 182 LYS   A O    1 
ATOM   2827 C CB   . LYS   A 1 185 ? 46.94488 7.41541   16.70923 1.000 5.13507   ? 182 LYS   A CB   1 
ATOM   2828 C CG   . LYS   A 1 185 ? 47.86750 6.87062   17.78652 1.000 14.35609  ? 182 LYS   A CG   1 
ATOM   2829 C CD   . LYS   A 1 185 ? 49.00801 6.05436   17.14405 1.000 10.60254  ? 182 LYS   A CD   1 
ATOM   2830 C CE   . LYS   A 1 185 ? 50.09699 5.73343   18.15333 1.000 35.56107  ? 182 LYS   A CE   1 
ATOM   2831 N NZ   . LYS   A 1 185 ? 51.10295 4.79406   17.56625 1.000 52.92515  ? 182 LYS   A NZ   1 
ATOM   2832 H H    A LYS   A 1 185 ? 45.49361 8.79223   15.35778 0.972 7.38818   ? 182 LYS   A H    1 
ATOM   2833 H H    B LYS   A 1 185 ? 45.49361 8.79223   15.35778 0.028 7.38818   ? 182 LYS   A H    1 
ATOM   2834 H HA   . LYS   A 1 185 ? 45.13079 7.60522   17.68152 1.000 4.40762   ? 182 LYS   A HA   1 
ATOM   2835 H HB2  . LYS   A 1 185 ? 46.61840 6.65919   16.19694 1.000 6.24767   ? 182 LYS   A HB2  1 
ATOM   2836 H HB3  . LYS   A 1 185 ? 47.47363 7.99743   16.14127 1.000 6.24767   ? 182 LYS   A HB3  1 
ATOM   2837 H HG2  . LYS   A 1 185 ? 48.25507 7.60558   18.28704 1.000 17.31289  ? 182 LYS   A HG2  1 
ATOM   2838 H HG3  . LYS   A 1 185 ? 47.36762 6.29074   18.38214 1.000 17.31289  ? 182 LYS   A HG3  1 
ATOM   2839 H HD2  . LYS   A 1 185 ? 48.65269 5.21894   16.80240 1.000 12.80863  ? 182 LYS   A HD2  1 
ATOM   2840 H HD3  . LYS   A 1 185 ? 49.40299 6.56705   16.42153 1.000 12.80863  ? 182 LYS   A HD3  1 
ATOM   2841 H HE2  . LYS   A 1 185 ? 50.55168 6.55079   18.41038 1.000 42.75887  ? 182 LYS   A HE2  1 
ATOM   2842 H HE3  . LYS   A 1 185 ? 49.70214 5.31394   18.93373 1.000 42.75887  ? 182 LYS   A HE3  1 
ATOM   2843 H HZ1  . LYS   A 1 185 ? 51.80080 4.71486   18.11291 1.000 63.59577  ? 182 LYS   A HZ1  1 
ATOM   2844 H HZ2  . LYS   A 1 185 ? 50.73687 3.99164   17.44707 1.000 63.59577  ? 182 LYS   A HZ2  1 
ATOM   2845 H HZ3  . LYS   A 1 185 ? 51.38509 5.10241   16.78049 1.000 63.59577  ? 182 LYS   A HZ3  1 
ATOM   2846 N N    . ALA   A 1 186 ? 46.65151 10.39222  17.76888 1.000 9.08302   ? 183 ALA   A N    1 
ATOM   2847 C CA   . ALA   A 1 186 ? 47.32244 11.31906  18.67570 1.000 10.88475  ? 183 ALA   A CA   1 
ATOM   2848 C C    . ALA   A 1 186 ? 46.45345 11.73476  19.85243 1.000 8.50979   ? 183 ALA   A C    1 
ATOM   2849 O O    . ALA   A 1 186 ? 46.95283 11.70220  20.99009 1.000 11.68193  ? 183 ALA   A O    1 
ATOM   2850 C CB   . ALA   A 1 186 ? 47.82407 12.54947  17.90170 1.000 9.69139   ? 183 ALA   A CB   1 
ATOM   2851 H H    . ALA   A 1 186 ? 46.59544 10.65395  16.95160 1.000 10.98521  ? 183 ALA   A H    1 
ATOM   2852 H HA   . ALA   A 1 186 ? 48.09393 10.85052  19.03090 1.000 13.14728  ? 183 ALA   A HA   1 
ATOM   2853 H HB1  . ALA   A 1 186 ? 48.24301 13.16465  18.52375 1.000 11.71526  ? 183 ALA   A HB1  1 
ATOM   2854 H HB2  . ALA   A 1 186 ? 48.46833 12.26256  17.23574 1.000 11.71526  ? 183 ALA   A HB2  1 
ATOM   2855 H HB3  . ALA   A 1 186 ? 47.06992 12.97926  17.46875 1.000 11.71526  ? 183 ALA   A HB3  1 
ATOM   2856 N N    . PRO   A 1 187 ? 45.19193 12.14673  19.67547 1.000 6.70207   ? 184 PRO   A N    1 
ATOM   2857 C CA   . PRO   A 1 187 ? 44.38509 12.56112  20.83243 1.000 4.67685   ? 184 PRO   A CA   1 
ATOM   2858 C C    . PRO   A 1 187 ? 44.04273 11.42427  21.78481 1.000 6.84915   ? 184 PRO   A C    1 
ATOM   2859 O O    . PRO   A 1 187 ? 43.41681 11.66851  22.81201 1.000 4.12339   ? 184 PRO   A O    1 
ATOM   2860 C CB   . PRO   A 1 187 ? 43.10374 13.14021  20.18518 1.000 6.65622   ? 184 PRO   A CB   1 
ATOM   2861 C CG   . PRO   A 1 187 ? 43.47161 13.43385  18.76717 1.000 10.63767  ? 184 PRO   A CG   1 
ATOM   2862 C CD   . PRO   A 1 187 ? 44.45729 12.33814  18.40707 1.000 5.38396   ? 184 PRO   A CD   1 
ATOM   2863 H HA   . PRO   A 1 187 ? 44.84123 13.26516  21.31942 1.000 5.69780   ? 184 PRO   A HA   1 
ATOM   2864 H HB2  . PRO   A 1 187 ? 42.38946 12.48536  20.22826 1.000 8.07305   ? 184 PRO   A HB2  1 
ATOM   2865 H HB3  . PRO   A 1 187 ? 42.83939 13.95045  20.64836 1.000 8.07305   ? 184 PRO   A HB3  1 
ATOM   2866 H HG2  . PRO   A 1 187 ? 42.68381 13.39535  18.20256 1.000 12.85078  ? 184 PRO   A HG2  1 
ATOM   2867 H HG3  . PRO   A 1 187 ? 43.88322 14.30984  18.70308 1.000 12.85078  ? 184 PRO   A HG3  1 
ATOM   2868 H HD2  . PRO   A 1 187 ? 43.99609 11.52610  18.14482 1.000 6.54634   ? 184 PRO   A HD2  1 
ATOM   2869 H HD3  . PRO   A 1 187 ? 45.05392 12.62459  17.69792 1.000 6.54634   ? 184 PRO   A HD3  1 
ATOM   2870 N N    . LEU   A 1 188 ? 44.39727 10.19212  21.48612 1.000 3.00286   ? 185 LEU   A N    1 
ATOM   2871 C CA   . LEU   A 1 188 ? 43.95020 9.09047   22.32443 1.000 3.91555   ? 185 LEU   A CA   1 
ATOM   2872 C C    . LEU   A 1 188 ? 44.86771 8.88106   23.50922 1.000 7.62245   ? 185 LEU   A C    1 
ATOM   2873 O O    . LEU   A 1 188 ? 44.47542 8.23638   24.48123 1.000 7.64470   ? 185 LEU   A O    1 
ATOM   2874 C CB   . LEU   A 1 188 ? 43.89526 7.81003   21.51434 1.000 6.90964   ? 185 LEU   A CB   1 
ATOM   2875 C CG   . LEU   A 1 188 ? 42.86315 7.76675   20.40126 1.000 4.46566   ? 185 LEU   A CG   1 
ATOM   2876 C CD1  . LEU   A 1 188 ? 43.08896 6.45405   19.64996 1.000 6.30465   ? 185 LEU   A CD1  1 
ATOM   2877 C CD2  . LEU   A 1 188 ? 41.47934 7.83517   20.95604 1.000 8.47184   ? 185 LEU   A CD2  1 
ATOM   2878 H H    . LEU   A 1 188 ? 44.88731 9.96636   20.81643 1.000 3.68902   ? 185 LEU   A H    1 
ATOM   2879 H HA   . LEU   A 1 188 ? 43.05600 9.28159   22.64810 1.000 4.78424   ? 185 LEU   A HA   1 
ATOM   2880 H HB2  . LEU   A 1 188 ? 44.76413 7.67421   21.10505 1.000 8.37715   ? 185 LEU   A HB2  1 
ATOM   2881 H HB3  . LEU   A 1 188 ? 43.69544 7.07848   22.11916 1.000 8.37715   ? 185 LEU   A HB3  1 
ATOM   2882 H HG   . LEU   A 1 188 ? 42.95296 8.52381   19.80152 1.000 5.44438   ? 185 LEU   A HG   1 
ATOM   2883 H HD11 . LEU   A 1 188 ? 42.45947 6.39907   18.91401 1.000 7.65117   ? 185 LEU   A HD11 1 
ATOM   2884 H HD12 . LEU   A 1 188 ? 43.99735 6.43684   19.31024 1.000 7.65117   ? 185 LEU   A HD12 1 
ATOM   2885 H HD13 . LEU   A 1 188 ? 42.94993 5.71298   20.26020 1.000 7.65117   ? 185 LEU   A HD13 1 
ATOM   2886 H HD21 . LEU   A 1 188 ? 40.84312 7.72278   20.23251 1.000 10.25179  ? 185 LEU   A HD21 1 
ATOM   2887 H HD22 . LEU   A 1 188 ? 41.36568 7.12728   21.60939 1.000 10.25179  ? 185 LEU   A HD22 1 
ATOM   2888 H HD23 . LEU   A 1 188 ? 41.35077 8.69888   21.37838 1.000 10.25179  ? 185 LEU   A HD23 1 
ATOM   2889 N N    . VAL   A 1 189 ? 46.09065 9.38657   23.42141 1.000 2.78530   ? 186 VAL   A N    1 
ATOM   2890 C CA   . VAL   A 1 189 ? 47.09043 9.24612   24.46828 1.000 4.50571   ? 186 VAL   A CA   1 
ATOM   2891 C C    . VAL   A 1 189 ? 47.43586 7.78161   24.63160 1.000 7.74554   ? 186 VAL   A C    1 
ATOM   2892 O O    . VAL   A 1 189 ? 47.41696 7.23926   25.74485 1.000 6.64044   ? 186 VAL   A O    1 
ATOM   2893 C CB   . VAL   A 1 189 ? 46.64156 9.84560   25.81323 1.000 4.11563   ? 186 VAL   A CB   1 
ATOM   2894 C CG1  . VAL   A 1 189 ? 47.89389 9.97545   26.71652 1.000 7.95865   ? 186 VAL   A CG1  1 
ATOM   2895 C CG2  . VAL   A 1 189 ? 45.96552 11.18176  25.62296 1.000 7.44375   ? 186 VAL   A CG2  1 
ATOM   2896 H H    . VAL   A 1 189 ? 46.37496 9.83036   22.74183 1.000 3.42795   ? 186 VAL   A H    1 
ATOM   2897 H HA   . VAL   A 1 189 ? 47.87999 9.73319   24.18500 1.000 5.49243   ? 186 VAL   A HA   1 
ATOM   2898 H HB   . VAL   A 1 189 ? 45.98704 9.26816   26.23641 1.000 5.02434   ? 186 VAL   A HB   1 
ATOM   2899 H HG11 . VAL   A 1 189 ? 47.65474 10.46413  27.51958 1.000 9.63596   ? 186 VAL   A HG11 1 
ATOM   2900 H HG12 . VAL   A 1 189 ? 48.20788 9.08800   26.95052 1.000 9.63596   ? 186 VAL   A HG12 1 
ATOM   2901 H HG13 . VAL   A 1 189 ? 48.58474 10.45360  26.23175 1.000 9.63596   ? 186 VAL   A HG13 1 
ATOM   2902 H HG21 . VAL   A 1 189 ? 45.78805 11.57260  26.49281 1.000 9.01808   ? 186 VAL   A HG21 1 
ATOM   2903 H HG22 . VAL   A 1 189 ? 46.55158 11.76240  25.11277 1.000 9.01808   ? 186 VAL   A HG22 1 
ATOM   2904 H HG23 . VAL   A 1 189 ? 45.13262 11.04889  25.14387 1.000 9.01808   ? 186 VAL   A HG23 1 
ATOM   2905 N N    . LEU   A 1 190 ? 47.72810 7.12903   23.51825 1.000 9.02210   ? 187 LEU   A N    1 
ATOM   2906 C CA   . LEU   A 1 190 ? 48.31966 5.80184   23.55494 1.000 13.40702  ? 187 LEU   A CA   1 
ATOM   2907 C C    . LEU   A 1 190 ? 49.81062 5.89052   23.87171 1.000 17.26359  ? 187 LEU   A C    1 
ATOM   2908 O O    . LEU   A 1 190 ? 50.46463 6.90013   23.59516 1.000 23.27024  ? 187 LEU   A O    1 
ATOM   2909 C CB   . LEU   A 1 190 ? 48.11579 5.10436   22.21414 1.000 12.17194  ? 187 LEU   A CB   1 
ATOM   2910 C CG   . LEU   A 1 190 ? 46.65707 4.76132   21.94198 1.000 15.49212  ? 187 LEU   A CG   1 
ATOM   2911 C CD1  . LEU   A 1 190 ? 46.48935 4.37345   20.49219 1.000 15.95406  ? 187 LEU   A CD1  1 
ATOM   2912 C CD2  . LEU   A 1 190 ? 46.23638 3.64054   22.86063 1.000 16.36089  ? 187 LEU   A CD2  1 
ATOM   2913 H H    . LEU   A 1 190 ? 47.59330 7.43359   22.72537 1.000 10.91211  ? 187 LEU   A H    1 
ATOM   2914 H HA   . LEU   A 1 190 ? 47.89484 5.27030   24.24624 1.000 16.17400  ? 187 LEU   A HA   1 
ATOM   2915 H HB2  . LEU   A 1 190 ? 48.42443 5.68958   21.50481 1.000 14.69192  ? 187 LEU   A HB2  1 
ATOM   2916 H HB3  . LEU   A 1 190 ? 48.62496 4.27877   22.20822 1.000 14.69192  ? 187 LEU   A HB3  1 
ATOM   2917 H HG   . LEU   A 1 190 ? 46.08485 5.52608   22.11112 1.000 18.67613  ? 187 LEU   A HG   1 
ATOM   2918 H HD11 . LEU   A 1 190 ? 45.64896 3.90062   20.38697 1.000 19.23045  ? 187 LEU   A HD11 1 
ATOM   2919 H HD12 . LEU   A 1 190 ? 46.48721 5.17681   19.94857 1.000 19.23045  ? 187 LEU   A HD12 1 
ATOM   2920 H HD13 . LEU   A 1 190 ? 47.22666 3.79960   20.23148 1.000 19.23045  ? 187 LEU   A HD13 1 
ATOM   2921 H HD21 . LEU   A 1 190 ? 45.33983 3.35685   22.62270 1.000 19.71865  ? 187 LEU   A HD21 1 
ATOM   2922 H HD22 . LEU   A 1 190 ? 46.85521 2.90041   22.75978 1.000 19.71865  ? 187 LEU   A HD22 1 
ATOM   2923 H HD23 . LEU   A 1 190 ? 46.24998 3.96067   23.77618 1.000 19.71865  ? 187 LEU   A HD23 1 
ATOM   2924 N N    . LYS   A 1 191 ? 50.34758 4.81573   24.46183 1.000 24.19249  ? 188 LYS   A N    1 
ATOM   2925 C CA   . LYS   A 1 191 ? 51.76048 4.81221   24.84192 1.000 41.81422  ? 188 LYS   A CA   1 
ATOM   2926 C C    . LYS   A 1 191 ? 52.65464 4.66139   23.61592 1.000 48.78287  ? 188 LYS   A C    1 
ATOM   2927 O O    . LYS   A 1 191 ? 53.56045 5.47733   23.38629 1.000 56.25446  ? 188 LYS   A O    1 
ATOM   2928 C CB   . LYS   A 1 191 ? 52.03780 3.69612   25.85456 1.000 39.09290  ? 188 LYS   A CB   1 
ATOM   2929 C CG   . LYS   A 1 191 ? 53.44434 3.74964   26.43318 1.000 48.18192  ? 188 LYS   A CG   1 
ATOM   2930 C CD   . LYS   A 1 191 ? 53.51494 3.12344   27.81201 1.000 53.52388  ? 188 LYS   A CD   1 
ATOM   2931 C CE   . LYS   A 1 191 ? 53.88694 1.64582   27.75282 1.000 85.17575  ? 188 LYS   A CE   1 
ATOM   2932 N NZ   . LYS   A 1 191 ? 54.60420 1.22164   29.00127 1.000 71.27519  ? 188 LYS   A NZ   1 
ATOM   2933 H H    . LYS   A 1 191 ? 49.92279 4.09167   24.64861 1.000 29.11657  ? 188 LYS   A H    1 
ATOM   2934 H HA   . LYS   A 1 191 ? 51.96936 5.65782   25.26877 1.000 50.26265  ? 188 LYS   A HA   1 
ATOM   2935 H HB2  . LYS   A 1 191 ? 51.40931 3.77512   26.58918 1.000 46.99706  ? 188 LYS   A HB2  1 
ATOM   2936 H HB3  . LYS   A 1 191 ? 51.92805 2.83851   25.41483 1.000 46.99706  ? 188 LYS   A HB3  1 
ATOM   2937 H HG2  . LYS   A 1 191 ? 54.04864 3.26513   25.84926 1.000 57.90389  ? 188 LYS   A HG2  1 
ATOM   2938 H HG3  . LYS   A 1 191 ? 53.72469 4.67536   26.50631 1.000 57.90389  ? 188 LYS   A HG3  1 
ATOM   2939 H HD2  . LYS   A 1 191 ? 54.18798 3.58380   28.33735 1.000 64.31424  ? 188 LYS   A HD2  1 
ATOM   2940 H HD3  . LYS   A 1 191 ? 52.64880 3.20012   28.24191 1.000 64.31424  ? 188 LYS   A HD3  1 
ATOM   2941 H HE2  . LYS   A 1 191 ? 53.08109 1.11302   27.66542 1.000 102.29649 ? 188 LYS   A HE2  1 
ATOM   2942 H HE3  . LYS   A 1 191 ? 54.47156 1.48995   26.99464 1.000 102.29649 ? 188 LYS   A HE3  1 
ATOM   2943 H HZ1  . LYS   A 1 191 ? 54.81374 0.35798   28.95342 1.000 85.61582  ? 188 LYS   A HZ1  1 
ATOM   2944 H HZ2  . LYS   A 1 191 ? 55.35143 1.69516   29.09883 1.000 85.61582  ? 188 LYS   A HZ2  1 
ATOM   2945 H HZ3  . LYS   A 1 191 ? 54.08381 1.35371   29.71109 1.000 85.61582  ? 188 LYS   A HZ3  1 
ATOM   2946 N N    . ASP   A 1 192 ? 52.40257 3.63186   22.80861 1.000 40.32494  ? 189 ASP   A N    1 
ATOM   2947 C CA   . ASP   A 1 192 ? 53.20182 3.38650   21.61097 1.000 71.01298  ? 189 ASP   A CA   1 
ATOM   2948 C C    . ASP   A 1 192 ? 52.31945 3.19359   20.38876 1.000 68.38846  ? 189 ASP   A C    1 
ATOM   2949 O O    . ASP   A 1 192 ? 52.26231 4.06374   19.52480 1.000 52.21351  ? 189 ASP   A O    1 
ATOM   2950 C CB   . ASP   A 1 192 ? 54.09841 2.16456   21.80871 1.000 63.53782  ? 189 ASP   A CB   1 
ATOM   2951 C CG   . ASP   A 1 192 ? 55.20492 2.41846   22.81262 1.000 76.16163  ? 189 ASP   A CG   1 
ATOM   2952 O OD1  . ASP   A 1 192 ? 55.78044 3.53067   22.78574 1.000 81.92007  ? 189 ASP   A OD1  1 
ATOM   2953 O OD2  . ASP   A 1 192 ? 55.49023 1.51679   23.63126 1.000 77.42203  ? 189 ASP   A OD2  1 
ATOM   2954 H H    . ASP   A 1 192 ? 51.77248 3.06002   22.93349 1.000 48.47551  ? 189 ASP   A H    1 
ATOM   2955 H HA   . ASP   A 1 192 ? 53.76935 4.15644   21.44974 1.000 85.30116  ? 189 ASP   A HA   1 
ATOM   2956 H HB2  . ASP   A 1 192 ? 53.56077 1.42512   22.13285 1.000 76.33097  ? 189 ASP   A HB2  1 
ATOM   2957 H HB3  . ASP   A 1 192 ? 54.50791 1.93047   20.96111 1.000 76.33097  ? 189 ASP   A HB3  1 
HETATM 2958 O O    . HOH   B 2 .   ? 51.06608 9.00959   24.23398 1.000 34.13717  ? 301 HOH   A O    1 
HETATM 2959 O O    . HOH   B 2 .   ? 48.44499 0.07323   11.41548 1.000 43.09636  ? 302 HOH   A O    1 
HETATM 2960 O O    . HOH   B 2 .   ? 30.10038 -6.27898  2.55453  1.000 33.79655  ? 303 HOH   A O    1 
HETATM 2961 O O    . HOH   B 2 .   ? 39.13742 -29.62841 8.60443  1.000 32.18852  ? 304 HOH   A O    1 
HETATM 2962 O O    . HOH   B 2 .   ? 37.61415 -3.05155  1.76260  1.000 18.11713  ? 305 HOH   A O    1 
HETATM 2963 O O    . HOH   B 2 .   ? 41.82300 -18.25198 1.10110  1.000 23.63771  ? 306 HOH   A O    1 
HETATM 2964 O O    . HOH   B 2 .   ? 25.22290 1.53810   20.12859 1.000 13.69295  ? 307 HOH   A O    1 
HETATM 2965 O O    . HOH   B 2 .   ? 25.97398 2.86963   17.78663 1.000 11.28908  ? 308 HOH   A O    1 
HETATM 2966 O O    . HOH   B 2 .   ? 17.08699 -2.40337  11.98817 1.000 21.83135  ? 309 HOH   A O    1 
HETATM 2967 O O    . HOH   B 2 .   ? 45.20478 -12.18054 9.95190  1.000 5.42819   ? 310 HOH   A O    1 
HETATM 2968 O O    . HOH   B 2 .   ? 45.54616 14.60636  15.48935 1.000 12.84341  ? 311 HOH   A O    1 
HETATM 2969 O O    . HOH   B 2 .   ? 44.30268 -13.65485 2.86439  1.000 33.58035  ? 312 HOH   A O    1 
HETATM 2970 O O    . HOH   B 2 .   ? 33.66572 -19.96330 18.13690 1.000 22.39825  ? 313 HOH   A O    1 
HETATM 2971 O O    . HOH   B 2 .   ? 45.83080 -1.81098  21.61741 1.000 9.30028   ? 314 HOH   A O    1 
HETATM 2972 O O    . HOH   B 2 .   ? 21.69891 -15.79707 12.96841 1.000 28.41659  ? 315 HOH   A O    1 
HETATM 2973 O O    . HOH   B 2 .   ? 24.16773 0.21369   7.20585  1.000 34.66759  ? 316 HOH   A O    1 
HETATM 2974 O O    . HOH   B 2 .   ? 19.22122 3.30599   14.66147 1.000 38.74981  ? 317 HOH   A O    1 
HETATM 2975 O O    . HOH   B 2 .   ? 14.72355 -6.20848  11.39708 1.000 36.91598  ? 318 HOH   A O    1 
HETATM 2976 O O    . HOH   B 2 .   ? 35.03866 -25.46591 9.09186  1.000 26.41715  ? 319 HOH   A O    1 
HETATM 2977 O O    . HOH   B 2 .   ? 30.62607 8.12330   11.37014 1.000 34.81497  ? 320 HOH   A O    1 
HETATM 2978 O O    . HOH   B 2 .   ? 38.51301 -27.81181 11.10218 1.000 19.43198  ? 321 HOH   A O    1 
HETATM 2979 O O    . HOH   B 2 .   ? 28.70601 -13.40429 30.62208 1.000 35.30047  ? 322 HOH   A O    1 
HETATM 2980 O O    . HOH   B 2 .   ? 47.38413 -25.35810 18.37895 1.000 20.62245  ? 323 HOH   A O    1 
HETATM 2981 O O    . HOH   B 2 .   ? 19.92652 -7.81947  19.48458 1.000 19.97209  ? 324 HOH   A O    1 
HETATM 2982 O O    . HOH   B 2 .   ? 45.53870 8.76224   5.26429  1.000 17.87722  ? 325 HOH   A O    1 
HETATM 2983 O O    . HOH   B 2 .   ? 29.51556 -10.13490 18.38860 1.000 3.66033   ? 326 HOH   A O    1 
HETATM 2984 O O    . HOH   B 2 .   ? 50.59218 -3.99132  17.03906 1.000 21.81132  ? 327 HOH   A O    1 
HETATM 2985 O O    . HOH   B 2 .   ? 43.64687 -2.19178  23.22200 1.000 35.40550  ? 328 HOH   A O    1 
HETATM 2986 O O    . HOH   B 2 .   ? 49.12093 -24.39295 8.56576  1.000 10.57391  ? 329 HOH   A O    1 
HETATM 2987 O O    . HOH   B 2 .   ? 50.97917 -11.60038 7.12879  1.000 27.13726  ? 330 HOH   A O    1 
HETATM 2988 O O    . HOH   B 2 .   ? 46.393   -28.305   14.297   1.000 11.02574  ? 331 HOH   A O    1 
HETATM 2989 O O    . HOH   B 2 .   ? 31.61699 -14.51173 26.20576 1.000 11.07738  ? 332 HOH   A O    1 
HETATM 2990 O O    . HOH   B 2 .   ? 38.81946 -17.38080 26.86930 1.000 22.08542  ? 333 HOH   A O    1 
HETATM 2991 O O    . HOH   B 2 .   ? 34.65884 -22.05797 15.26827 1.000 26.92493  ? 334 HOH   A O    1 
HETATM 2992 O O    . HOH   B 2 .   ? 41.54618 -23.30215 21.98906 1.000 19.32169  ? 335 HOH   A O    1 
HETATM 2993 O O    . HOH   B 2 .   ? 44.03485 -27.96319 17.17414 1.000 18.21090  ? 336 HOH   A O    1 
HETATM 2994 O O    . HOH   B 2 .   ? 46.284   -29.984   7.520    1.000 7.49269   ? 337 HOH   A O    1 
HETATM 2995 O O    B HOH   B 2 .   ? 50.10098 -18.02938 21.51381 0.931 14.73949  ? 338 HOH   A O    1 
HETATM 2996 O O    . HOH   B 2 .   ? 31.28406 2.12842   1.07418  1.000 29.32623  ? 339 HOH   A O    1 
HETATM 2997 O O    . HOH   B 2 .   ? 49.53778 5.55545   10.95017 1.000 36.77277  ? 340 HOH   A O    1 
HETATM 2998 O O    . HOH   B 2 .   ? 23.32050 -6.39086  32.39158 1.000 23.17581  ? 341 HOH   A O    1 
HETATM 2999 O O    . HOH   B 2 .   ? 48.24415 8.74883   21.24541 1.000 12.18135  ? 342 HOH   A O    1 
HETATM 3000 O O    . HOH   B 2 .   ? 21.73602 -19.91281 11.59629 1.000 35.15279  ? 343 HOH   A O    1 
HETATM 3001 O O    . HOH   B 2 .   ? 49.94101 9.97032   16.07244 1.000 25.64468  ? 344 HOH   A O    1 
HETATM 3002 O O    . HOH   B 2 .   ? 46.48356 1.83874   3.36819  1.000 23.54047  ? 345 HOH   A O    1 
HETATM 3003 O O    . HOH   B 2 .   ? 22.44557 2.72956   18.58118 1.000 29.63790  ? 346 HOH   A O    1 
HETATM 3004 O O    . HOH   B 2 .   ? 31.96172 10.36433  13.20765 1.000 13.82829  ? 347 HOH   A O    1 
HETATM 3005 O O    . HOH   B 2 .   ? 25.74448 -12.15446 27.89986 1.000 20.29055  ? 348 HOH   A O    1 
HETATM 3006 O O    . HOH   B 2 .   ? 31.49542 -11.81924 19.28449 1.000 6.34529   ? 349 HOH   A O    1 
HETATM 3007 O O    . HOH   B 2 .   ? 27.68880 1.85922   7.77142  1.000 23.89361  ? 350 HOH   A O    1 
HETATM 3008 O O    . HOH   B 2 .   ? 42.36961 -24.80671 10.96106 1.000 4.09250   ? 351 HOH   A O    1 
HETATM 3009 O O    . HOH   B 2 .   ? 38.36180 -20.57221 2.60203  1.000 15.08962  ? 352 HOH   A O    1 
HETATM 3010 O O    . HOH   B 2 .   ? 17.30107 -7.54972  25.38090 1.000 37.57054  ? 353 HOH   A O    1 
HETATM 3011 O O    . HOH   B 2 .   ? 34.13898 -19.41853 20.95168 1.000 31.28944  ? 354 HOH   A O    1 
HETATM 3012 O O    . HOH   B 2 .   ? 28.84683 5.93720   12.18254 1.000 8.47293   ? 355 HOH   A O    1 
HETATM 3013 O O    . HOH   B 2 .   ? 44.71070 -24.17837 4.09934  1.000 10.03650  ? 356 HOH   A O    1 
HETATM 3014 O O    . HOH   B 2 .   ? 26.32692 -12.06483 30.66083 1.000 34.32678  ? 357 HOH   A O    1 
HETATM 3015 O O    . HOH   B 2 .   ? 14.66128 -6.51397  15.08653 1.000 35.38267  ? 358 HOH   A O    1 
HETATM 3016 O O    . HOH   B 2 .   ? 23.60181 -17.67922 16.07936 1.000 26.26609  ? 359 HOH   A O    1 
HETATM 3017 O O    . HOH   B 2 .   ? 42.87886 -25.88813 3.69596  1.000 17.81960  ? 360 HOH   A O    1 
HETATM 3018 O O    . HOH   B 2 .   ? 28.92167 -8.92553  2.95000  1.000 24.59450  ? 361 HOH   A O    1 
HETATM 3019 O O    . HOH   B 2 .   ? 41.976   12.345    11.326   1.000 10.48031  ? 362 HOH   A O    1 
HETATM 3020 O O    . HOH   B 2 .   ? 48.79290 5.17601   3.64328  1.000 32.41363  ? 363 HOH   A O    1 
HETATM 3021 O O    . HOH   B 2 .   ? 45.90973 -1.22425  24.75735 1.000 34.52883  ? 364 HOH   A O    1 
HETATM 3022 O O    . HOH   B 2 .   ? 53.42740 -10.57819 20.51472 1.000 45.89440  ? 365 HOH   A O    1 
HETATM 3023 O O    . HOH   B 2 .   ? 37.73798 -26.14372 15.87777 1.000 27.24161  ? 366 HOH   A O    1 
HETATM 3024 O O    . HOH   B 2 .   ? 22.81508 -12.65894 19.94044 1.000 20.17908  ? 367 HOH   A O    1 
HETATM 3025 O O    . HOH   B 2 .   ? 46.42883 -2.16272  8.25245  1.000 17.21558  ? 368 HOH   A O    1 
HETATM 3026 O O    . HOH   B 2 .   ? 30.87543 -23.55756 6.53333  1.000 28.10300  ? 369 HOH   A O    1 
HETATM 3027 O O    . HOH   B 2 .   ? 37.92297 12.35947  23.38052 1.000 25.17079  ? 370 HOH   A O    1 
HETATM 3028 O O    . HOH   B 2 .   ? 54.51733 -15.41159 15.05289 1.000 21.97812  ? 371 HOH   A O    1 
HETATM 3029 O O    . HOH   B 2 .   ? 48.39897 -20.73852 23.00593 1.000 24.86618  ? 372 HOH   A O    1 
HETATM 3030 O O    . HOH   B 2 .   ? 35.74572 -6.24715  -6.00277 1.000 38.65779  ? 373 HOH   A O    1 
HETATM 3031 O O    . HOH   B 2 .   ? 51.20517 -11.47855 21.77473 1.000 26.38809  ? 374 HOH   A O    1 
HETATM 3032 O O    . HOH   B 2 .   ? 21.22072 -10.04510 24.89878 1.000 19.63601  ? 375 HOH   A O    1 
HETATM 3033 O O    . HOH   B 2 .   ? 22.11610 -9.78611  18.89323 1.000 19.15635  ? 376 HOH   A O    1 
HETATM 3034 O O    . HOH   B 2 .   ? 48.20398 -2.66708  25.27447 1.000 22.61889  ? 377 HOH   A O    1 
HETATM 3035 O O    . HOH   B 2 .   ? 44.56409 -22.74637 22.68479 1.000 16.91501  ? 378 HOH   A O    1 
HETATM 3036 O O    . HOH   B 2 .   ? 53.265   -20.753   12.157   1.000 30.64184  ? 379 HOH   A O    1 
HETATM 3037 O O    . HOH   B 2 .   ? 31.00037 -5.10033  -4.83598 1.000 42.82745  ? 380 HOH   A O    1 
HETATM 3038 O O    . HOH   B 2 .   ? 53.46777 -7.95599  17.76742 1.000 19.32197  ? 381 HOH   A O    1 
HETATM 3039 O O    . HOH   B 2 .   ? 47.95452 -0.52769  14.21622 1.000 27.66918  ? 382 HOH   A O    1 
HETATM 3040 O O    . HOH   B 2 .   ? 26.99628 -15.50661 0.33105  1.000 34.45669  ? 383 HOH   A O    1 
HETATM 3041 O O    . HOH   B 2 .   ? 47.65109 13.77204  23.14382 1.000 36.39852  ? 384 HOH   A O    1 
HETATM 3042 O O    . HOH   B 2 .   ? 40.75438 -15.49384 1.23433  1.000 34.85075  ? 385 HOH   A O    1 
HETATM 3043 O O    . HOH   B 2 .   ? 18.79061 -9.71767  12.75141 1.000 24.24741  ? 386 HOH   A O    1 
HETATM 3044 O O    . HOH   B 2 .   ? 28.55315 -23.17395 10.90917 1.000 30.44420  ? 387 HOH   A O    1 
HETATM 3045 O O    . HOH   B 2 .   ? 55.40731 -12.24606 11.01577 1.000 36.45314  ? 388 HOH   A O    1 
HETATM 3046 O O    . HOH   B 2 .   ? 48.38201 8.53105   4.06024  1.000 34.47287  ? 389 HOH   A O    1 
HETATM 3047 O O    . HOH   B 2 .   ? 37.76126 -0.05382  1.06588  1.000 37.17831  ? 390 HOH   A O    1 
HETATM 3048 O O    . HOH   B 2 .   ? 19.85198 2.51045   18.89953 1.000 37.27232  ? 391 HOH   A O    1 
HETATM 3049 O O    . HOH   B 2 .   ? 35.46592 7.43739   5.24252  1.000 32.80006  ? 392 HOH   A O    1 
HETATM 3050 O O    . HOH   B 2 .   ? 26.45750 -18.77912 22.82074 1.000 38.86455  ? 393 HOH   A O    1 
HETATM 3051 O O    . HOH   B 2 .   ? 24.63846 3.81429   12.43122 1.000 35.30070  ? 394 HOH   A O    1 
HETATM 3052 O O    . HOH   B 2 .   ? 51.65729 -6.47504  15.55575 1.000 29.17481  ? 395 HOH   A O    1 
HETATM 3053 O O    . HOH   B 2 .   ? 39.99020 12.67427  22.46582 1.000 28.85234  ? 396 HOH   A O    1 
HETATM 3054 O O    . HOH   B 2 .   ? 42.80109 -23.28646 25.74355 1.000 45.99222  ? 397 HOH   A O    1 
HETATM 3055 O O    . HOH   B 2 .   ? 25.10885 -16.55684 24.50372 1.000 31.01549  ? 398 HOH   A O    1 
HETATM 3056 O O    . HOH   B 2 .   ? 17.23953 0.36420   12.51666 1.000 36.61772  ? 399 HOH   A O    1 
HETATM 3057 O O    . HOH   B 2 .   ? 38.893   11.460    8.311    1.000 28.33492  ? 400 HOH   A O    1 
HETATM 3058 O O    . HOH   B 2 .   ? 24.21827 -19.30854 4.54218  1.000 36.47674  ? 401 HOH   A O    1 
HETATM 3059 O O    . HOH   B 2 .   ? 35.073   -14.141   26.845   1.000 5.96812   ? 402 HOH   A O    1 
HETATM 3060 O O    . HOH   B 2 .   ? 52.03848 -9.31076  22.90226 1.000 26.64599  ? 403 HOH   A O    1 
HETATM 3061 O O    . HOH   B 2 .   ? 15.82759 -10.10252 12.68372 1.000 42.93140  ? 404 HOH   A O    1 
HETATM 3062 O O    . HOH   B 2 .   ? 40.70357 -28.45666 18.33828 1.000 37.35874  ? 405 HOH   A O    1 
HETATM 3063 O O    . HOH   B 2 .   ? 38.19195 -27.77523 17.95058 1.000 36.96255  ? 406 HOH   A O    1 
HETATM 3064 O O    . HOH   B 2 .   ? 18.81404 -9.30548  21.41768 1.000 39.91392  ? 407 HOH   A O    1 
HETATM 3065 O O    . HOH   B 2 .   ? 38.85948 -20.57906 27.06052 1.000 30.48945  ? 408 HOH   A O    1 
HETATM 3066 O O    . HOH   B 2 .   ? 17.89317 0.05238   20.87874 1.000 44.50919  ? 409 HOH   A O    1 
HETATM 3067 O O    . HOH   B 2 .   ? 45.88886 -15.91604 28.42771 1.000 34.57648  ? 410 HOH   A O    1 
HETATM 3068 O O    . HOH   B 2 .   ? 49.10467 1.68340   16.17857 1.000 41.02073  ? 411 HOH   A O    1 
HETATM 3069 O O    . HOH   B 2 .   ? 47.01644 -8.94789  -0.36848 1.000 43.69438  ? 412 HOH   A O    1 
HETATM 3070 O O    . HOH   B 2 .   ? 50.52611 9.22894   18.97420 1.000 35.79919  ? 413 HOH   A O    1 
HETATM 3071 O O    . HOH   B 2 .   ? 49.83799 -2.19236  15.01124 1.000 42.72341  ? 414 HOH   A O    1 
HETATM 3072 O O    . HOH   B 2 .   ? 44.89785 -8.62743  -1.43120 1.000 41.93087  ? 415 HOH   A O    1 
HETATM 3073 O O    . HOH   B 2 .   ? 49.36771 -2.84996  12.57799 1.000 37.71930  ? 416 HOH   A O    1 
HETATM 3074 O O    . HOH   B 2 .   ? 17.71230 2.23591   21.85545 1.000 49.15776  ? 417 HOH   A O    1 
# 
