data_9CCY
# 
_entry.id   9CCY 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CCY         pdb_00009ccy 10.2210/pdb9ccy/pdb 
WWPDB D_1000285070 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-12 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CCY 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              peizhou@biochem.duke.edu 
_pdbx_contact_author.name_first         Pei 
_pdbx_contact_author.name_last          Zhou 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7823-3416 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Cochrane, C.S.' 1 ? 
'Zhou, P.'       2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Jacs Au' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2691-3704 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            4 
_citation.language                  ? 
_citation.page_first                4383 
_citation.page_last                 4393 
_citation.title                     
'Design and Evaluation of Pyridinyl Sulfonyl Piperazine LpxH Inhibitors with Potent Antibiotic Activity Against Enterobacterales.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/jacsau.4c00731 
_citation.pdbx_database_id_PubMed   39610720 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ennis, A.F.'    1  ?                   
primary 'Cochrane, C.S.' 2  ?                   
primary 'Dome, P.A.'     3  ?                   
primary 'Jeong, P.'      4  ?                   
primary 'Yu, J.'         5  0000-0001-8487-5565 
primary 'Lee, H.'        6  ?                   
primary 'Williams, C.S.' 7  ?                   
primary 'Ha, Y.'         8  0000-0001-5684-8420 
primary 'Yang, W.'       9  0000-0001-5576-2828 
primary 'Zhou, P.'       10 0000-0002-7823-3416 
primary 'Hong, J.'       11 0000-0002-5253-0949 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'UDP-2,3-diacylglucosamine hydrolase'                                                                   
29627.680 1  3.6.1.54 ? ? ? 
2 non-polymer syn '1-(5-{4-[6-(trifluoromethyl)pyridin-2-yl]piperazine-1-sulfonyl}-2,3-dihydro-1H-indol-1-yl)ethan-1-one' 454.466 
1  ?        ? ? ? 
3 non-polymer syn 'MANGANESE (II) ION'                                                                                    54.938 2 
?        ? ? ? 
4 water       nat water                                                                                                   18.015 
85 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'UDP-2,3-diacylglucosamine diphosphatase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MATLFIADLHLQTEEPAITAGFLRFLQGEARQADALYILGDLFEAWIGDDDPNPLHQQIASAIKAVVDAGVPCYFIHGNR
DFLVGQRFARQSGMILLAEEERLDLYGREVLIMHGDTLCTDDQGYLAFRAKVHTPWIQRLFLALPLFIRHRIAARMRADS
KAANSSKSMEIMDVNPQAVVDAMERHHVQWLIHGHTHRPAVHELQANGQPAWRVVLGAWHSEGSMVKVTPDDVELIHFPF
LEENLYFQSHHHHHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MATLFIADLHLQTEEPAITAGFLRFLQGEARQADALYILGDLFEAWIGDDDPNPLHQQIASAIKAVVDAGVPCYFIHGNR
DFLVGQRFARQSGMILLAEEERLDLYGREVLIMHGDTLCTDDQGYLAFRAKVHTPWIQRLFLALPLFIRHRIAARMRADS
KAANSSKSMEIMDVNPQAVVDAMERHHVQWLIHGHTHRPAVHELQANGQPAWRVVLGAWHSEGSMVKVTPDDVELIHFPF
LEENLYFQSHHHHHHHHHH
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '1-(5-{4-[6-(trifluoromethyl)pyridin-2-yl]piperazine-1-sulfonyl}-2,3-dihydro-1H-indol-1-yl)ethan-1-one' A1AVY 
3 'MANGANESE (II) ION'                                                                                    MN    
4 water                                                                                                   HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   THR n 
1 4   LEU n 
1 5   PHE n 
1 6   ILE n 
1 7   ALA n 
1 8   ASP n 
1 9   LEU n 
1 10  HIS n 
1 11  LEU n 
1 12  GLN n 
1 13  THR n 
1 14  GLU n 
1 15  GLU n 
1 16  PRO n 
1 17  ALA n 
1 18  ILE n 
1 19  THR n 
1 20  ALA n 
1 21  GLY n 
1 22  PHE n 
1 23  LEU n 
1 24  ARG n 
1 25  PHE n 
1 26  LEU n 
1 27  GLN n 
1 28  GLY n 
1 29  GLU n 
1 30  ALA n 
1 31  ARG n 
1 32  GLN n 
1 33  ALA n 
1 34  ASP n 
1 35  ALA n 
1 36  LEU n 
1 37  TYR n 
1 38  ILE n 
1 39  LEU n 
1 40  GLY n 
1 41  ASP n 
1 42  LEU n 
1 43  PHE n 
1 44  GLU n 
1 45  ALA n 
1 46  TRP n 
1 47  ILE n 
1 48  GLY n 
1 49  ASP n 
1 50  ASP n 
1 51  ASP n 
1 52  PRO n 
1 53  ASN n 
1 54  PRO n 
1 55  LEU n 
1 56  HIS n 
1 57  GLN n 
1 58  GLN n 
1 59  ILE n 
1 60  ALA n 
1 61  SER n 
1 62  ALA n 
1 63  ILE n 
1 64  LYS n 
1 65  ALA n 
1 66  VAL n 
1 67  VAL n 
1 68  ASP n 
1 69  ALA n 
1 70  GLY n 
1 71  VAL n 
1 72  PRO n 
1 73  CYS n 
1 74  TYR n 
1 75  PHE n 
1 76  ILE n 
1 77  HIS n 
1 78  GLY n 
1 79  ASN n 
1 80  ARG n 
1 81  ASP n 
1 82  PHE n 
1 83  LEU n 
1 84  VAL n 
1 85  GLY n 
1 86  GLN n 
1 87  ARG n 
1 88  PHE n 
1 89  ALA n 
1 90  ARG n 
1 91  GLN n 
1 92  SER n 
1 93  GLY n 
1 94  MET n 
1 95  ILE n 
1 96  LEU n 
1 97  LEU n 
1 98  ALA n 
1 99  GLU n 
1 100 GLU n 
1 101 GLU n 
1 102 ARG n 
1 103 LEU n 
1 104 ASP n 
1 105 LEU n 
1 106 TYR n 
1 107 GLY n 
1 108 ARG n 
1 109 GLU n 
1 110 VAL n 
1 111 LEU n 
1 112 ILE n 
1 113 MET n 
1 114 HIS n 
1 115 GLY n 
1 116 ASP n 
1 117 THR n 
1 118 LEU n 
1 119 CYS n 
1 120 THR n 
1 121 ASP n 
1 122 ASP n 
1 123 GLN n 
1 124 GLY n 
1 125 TYR n 
1 126 LEU n 
1 127 ALA n 
1 128 PHE n 
1 129 ARG n 
1 130 ALA n 
1 131 LYS n 
1 132 VAL n 
1 133 HIS n 
1 134 THR n 
1 135 PRO n 
1 136 TRP n 
1 137 ILE n 
1 138 GLN n 
1 139 ARG n 
1 140 LEU n 
1 141 PHE n 
1 142 LEU n 
1 143 ALA n 
1 144 LEU n 
1 145 PRO n 
1 146 LEU n 
1 147 PHE n 
1 148 ILE n 
1 149 ARG n 
1 150 HIS n 
1 151 ARG n 
1 152 ILE n 
1 153 ALA n 
1 154 ALA n 
1 155 ARG n 
1 156 MET n 
1 157 ARG n 
1 158 ALA n 
1 159 ASP n 
1 160 SER n 
1 161 LYS n 
1 162 ALA n 
1 163 ALA n 
1 164 ASN n 
1 165 SER n 
1 166 SER n 
1 167 LYS n 
1 168 SER n 
1 169 MET n 
1 170 GLU n 
1 171 ILE n 
1 172 MET n 
1 173 ASP n 
1 174 VAL n 
1 175 ASN n 
1 176 PRO n 
1 177 GLN n 
1 178 ALA n 
1 179 VAL n 
1 180 VAL n 
1 181 ASP n 
1 182 ALA n 
1 183 MET n 
1 184 GLU n 
1 185 ARG n 
1 186 HIS n 
1 187 HIS n 
1 188 VAL n 
1 189 GLN n 
1 190 TRP n 
1 191 LEU n 
1 192 ILE n 
1 193 HIS n 
1 194 GLY n 
1 195 HIS n 
1 196 THR n 
1 197 HIS n 
1 198 ARG n 
1 199 PRO n 
1 200 ALA n 
1 201 VAL n 
1 202 HIS n 
1 203 GLU n 
1 204 LEU n 
1 205 GLN n 
1 206 ALA n 
1 207 ASN n 
1 208 GLY n 
1 209 GLN n 
1 210 PRO n 
1 211 ALA n 
1 212 TRP n 
1 213 ARG n 
1 214 VAL n 
1 215 VAL n 
1 216 LEU n 
1 217 GLY n 
1 218 ALA n 
1 219 TRP n 
1 220 HIS n 
1 221 SER n 
1 222 GLU n 
1 223 GLY n 
1 224 SER n 
1 225 MET n 
1 226 VAL n 
1 227 LYS n 
1 228 VAL n 
1 229 THR n 
1 230 PRO n 
1 231 ASP n 
1 232 ASP n 
1 233 VAL n 
1 234 GLU n 
1 235 LEU n 
1 236 ILE n 
1 237 HIS n 
1 238 PHE n 
1 239 PRO n 
1 240 PHE n 
1 241 LEU n 
1 242 GLU n 
1 243 GLU n 
1 244 ASN n 
1 245 LEU n 
1 246 TYR n 
1 247 PHE n 
1 248 GLN n 
1 249 SER n 
1 250 HIS n 
1 251 HIS n 
1 252 HIS n 
1 253 HIS n 
1 254 HIS n 
1 255 HIS n 
1 256 HIS n 
1 257 HIS n 
1 258 HIS n 
1 259 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   259 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'lpxH_1, lpxH, C3483_19950, NCTC9128_00880, SAMEA104305404_03891' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Klebsiella pneumoniae' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     573 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1AVY non-polymer         . 
'1-(5-{4-[6-(trifluoromethyl)pyridin-2-yl]piperazine-1-sulfonyl}-2,3-dihydro-1H-indol-1-yl)ethan-1-one' ? 'C20 H21 F3 N4 O3 S' 
454.466 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'         89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1'     175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'        132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'         133.103 
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'       121.158 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'       146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'         147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'         75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1'     156.162 
HOH   non-polymer         . WATER ? 'H2 O'               18.015  
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'        131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'        131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1'     147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'      149.211 
MN    non-polymer         . 'MANGANESE (II) ION' ? 'Mn 2'               54.938  
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'        165.189 
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'         115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'         105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'         119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'      204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'        181.189 
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'        117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   2   ALA ALA A . n 
A 1 3   THR 3   3   3   THR THR A . n 
A 1 4   LEU 4   4   4   LEU LEU A . n 
A 1 5   PHE 5   5   5   PHE PHE A . n 
A 1 6   ILE 6   6   6   ILE ILE A . n 
A 1 7   ALA 7   7   7   ALA ALA A . n 
A 1 8   ASP 8   8   8   ASP ASP A . n 
A 1 9   LEU 9   9   9   LEU LEU A . n 
A 1 10  HIS 10  10  10  HIS HIS A . n 
A 1 11  LEU 11  11  11  LEU LEU A . n 
A 1 12  GLN 12  12  12  GLN GLN A . n 
A 1 13  THR 13  13  13  THR THR A . n 
A 1 14  GLU 14  14  14  GLU GLU A . n 
A 1 15  GLU 15  15  15  GLU GLU A . n 
A 1 16  PRO 16  16  16  PRO PRO A . n 
A 1 17  ALA 17  17  17  ALA ALA A . n 
A 1 18  ILE 18  18  18  ILE ILE A . n 
A 1 19  THR 19  19  19  THR THR A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  GLY 21  21  21  GLY GLY A . n 
A 1 22  PHE 22  22  22  PHE PHE A . n 
A 1 23  LEU 23  23  23  LEU LEU A . n 
A 1 24  ARG 24  24  24  ARG ARG A . n 
A 1 25  PHE 25  25  25  PHE PHE A . n 
A 1 26  LEU 26  26  26  LEU LEU A . n 
A 1 27  GLN 27  27  27  GLN GLN A . n 
A 1 28  GLY 28  28  28  GLY GLY A . n 
A 1 29  GLU 29  29  29  GLU GLU A . n 
A 1 30  ALA 30  30  30  ALA ALA A . n 
A 1 31  ARG 31  31  31  ARG ARG A . n 
A 1 32  GLN 32  32  32  GLN GLN A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  ASP 34  34  34  ASP ASP A . n 
A 1 35  ALA 35  35  35  ALA ALA A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  TYR 37  37  37  TYR TYR A . n 
A 1 38  ILE 38  38  38  ILE ILE A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  GLY 40  40  40  GLY GLY A . n 
A 1 41  ASP 41  41  41  ASP ASP A . n 
A 1 42  LEU 42  42  42  LEU LEU A . n 
A 1 43  PHE 43  43  43  PHE PHE A . n 
A 1 44  GLU 44  44  44  GLU GLU A . n 
A 1 45  ALA 45  45  45  ALA ALA A . n 
A 1 46  TRP 46  46  46  TRP TRP A . n 
A 1 47  ILE 47  47  47  ILE ILE A . n 
A 1 48  GLY 48  48  48  GLY GLY A . n 
A 1 49  ASP 49  49  49  ASP ASP A . n 
A 1 50  ASP 50  50  50  ASP ASP A . n 
A 1 51  ASP 51  51  51  ASP ASP A . n 
A 1 52  PRO 52  52  52  PRO PRO A . n 
A 1 53  ASN 53  53  53  ASN ASN A . n 
A 1 54  PRO 54  54  54  PRO PRO A . n 
A 1 55  LEU 55  55  55  LEU LEU A . n 
A 1 56  HIS 56  56  56  HIS HIS A . n 
A 1 57  GLN 57  57  57  GLN GLN A . n 
A 1 58  GLN 58  58  58  GLN GLN A . n 
A 1 59  ILE 59  59  59  ILE ILE A . n 
A 1 60  ALA 60  60  60  ALA ALA A . n 
A 1 61  SER 61  61  61  SER SER A . n 
A 1 62  ALA 62  62  62  ALA ALA A . n 
A 1 63  ILE 63  63  63  ILE ILE A . n 
A 1 64  LYS 64  64  64  LYS LYS A . n 
A 1 65  ALA 65  65  65  ALA ALA A . n 
A 1 66  VAL 66  66  66  VAL VAL A . n 
A 1 67  VAL 67  67  67  VAL VAL A . n 
A 1 68  ASP 68  68  68  ASP ASP A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  VAL 71  71  71  VAL VAL A . n 
A 1 72  PRO 72  72  72  PRO PRO A . n 
A 1 73  CYS 73  73  73  CYS CYS A . n 
A 1 74  TYR 74  74  74  TYR TYR A . n 
A 1 75  PHE 75  75  75  PHE PHE A . n 
A 1 76  ILE 76  76  76  ILE ILE A . n 
A 1 77  HIS 77  77  77  HIS HIS A . n 
A 1 78  GLY 78  78  78  GLY GLY A . n 
A 1 79  ASN 79  79  79  ASN ASN A . n 
A 1 80  ARG 80  80  80  ARG ARG A . n 
A 1 81  ASP 81  81  81  ASP ASP A . n 
A 1 82  PHE 82  82  82  PHE PHE A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  GLY 85  85  85  GLY GLY A . n 
A 1 86  GLN 86  86  86  GLN GLN A . n 
A 1 87  ARG 87  87  87  ARG ARG A . n 
A 1 88  PHE 88  88  88  PHE PHE A . n 
A 1 89  ALA 89  89  89  ALA ALA A . n 
A 1 90  ARG 90  90  90  ARG ARG A . n 
A 1 91  GLN 91  91  91  GLN GLN A . n 
A 1 92  SER 92  92  92  SER SER A . n 
A 1 93  GLY 93  93  93  GLY GLY A . n 
A 1 94  MET 94  94  94  MET MET A . n 
A 1 95  ILE 95  95  95  ILE ILE A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  GLU 99  99  99  GLU GLU A . n 
A 1 100 GLU 100 100 100 GLU GLU A . n 
A 1 101 GLU 101 101 101 GLU GLU A . n 
A 1 102 ARG 102 102 102 ARG ARG A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 ASP 104 104 104 ASP ASP A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 TYR 106 106 106 TYR TYR A . n 
A 1 107 GLY 107 107 107 GLY GLY A . n 
A 1 108 ARG 108 108 108 ARG ARG A . n 
A 1 109 GLU 109 109 109 GLU GLU A . n 
A 1 110 VAL 110 110 110 VAL VAL A . n 
A 1 111 LEU 111 111 111 LEU LEU A . n 
A 1 112 ILE 112 112 112 ILE ILE A . n 
A 1 113 MET 113 113 113 MET MET A . n 
A 1 114 HIS 114 114 114 HIS HIS A . n 
A 1 115 GLY 115 115 115 GLY GLY A . n 
A 1 116 ASP 116 116 116 ASP ASP A . n 
A 1 117 THR 117 117 117 THR THR A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 CYS 119 119 119 CYS CYS A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 ASP 121 121 121 ASP ASP A . n 
A 1 122 ASP 122 122 122 ASP ASP A . n 
A 1 123 GLN 123 123 123 GLN GLN A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 TYR 125 125 125 TYR TYR A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 ALA 127 127 127 ALA ALA A . n 
A 1 128 PHE 128 128 128 PHE PHE A . n 
A 1 129 ARG 129 129 129 ARG ARG A . n 
A 1 130 ALA 130 130 130 ALA ALA A . n 
A 1 131 LYS 131 131 131 LYS LYS A . n 
A 1 132 VAL 132 132 132 VAL VAL A . n 
A 1 133 HIS 133 133 133 HIS HIS A . n 
A 1 134 THR 134 134 134 THR THR A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 TRP 136 136 136 TRP TRP A . n 
A 1 137 ILE 137 137 137 ILE ILE A . n 
A 1 138 GLN 138 138 138 GLN GLN A . n 
A 1 139 ARG 139 139 139 ARG ARG A . n 
A 1 140 LEU 140 140 140 LEU LEU A . n 
A 1 141 PHE 141 141 141 PHE PHE A . n 
A 1 142 LEU 142 142 142 LEU LEU A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 LEU 144 144 144 LEU LEU A . n 
A 1 145 PRO 145 145 145 PRO PRO A . n 
A 1 146 LEU 146 146 146 LEU LEU A . n 
A 1 147 PHE 147 147 147 PHE PHE A . n 
A 1 148 ILE 148 148 148 ILE ILE A . n 
A 1 149 ARG 149 149 149 ARG ARG A . n 
A 1 150 HIS 150 150 150 HIS HIS A . n 
A 1 151 ARG 151 151 151 ARG ARG A . n 
A 1 152 ILE 152 152 152 ILE ILE A . n 
A 1 153 ALA 153 153 153 ALA ALA A . n 
A 1 154 ALA 154 154 154 ALA ALA A . n 
A 1 155 ARG 155 155 155 ARG ARG A . n 
A 1 156 MET 156 156 156 MET MET A . n 
A 1 157 ARG 157 157 157 ARG ARG A . n 
A 1 158 ALA 158 158 158 ALA ALA A . n 
A 1 159 ASP 159 159 159 ASP ASP A . n 
A 1 160 SER 160 160 160 SER SER A . n 
A 1 161 LYS 161 161 161 LYS LYS A . n 
A 1 162 ALA 162 162 162 ALA ALA A . n 
A 1 163 ALA 163 163 ?   ?   ?   A . n 
A 1 164 ASN 164 164 ?   ?   ?   A . n 
A 1 165 SER 165 165 ?   ?   ?   A . n 
A 1 166 SER 166 166 ?   ?   ?   A . n 
A 1 167 LYS 167 167 ?   ?   ?   A . n 
A 1 168 SER 168 168 ?   ?   ?   A . n 
A 1 169 MET 169 169 ?   ?   ?   A . n 
A 1 170 GLU 170 170 170 GLU GLU A . n 
A 1 171 ILE 171 171 171 ILE ILE A . n 
A 1 172 MET 172 172 172 MET MET A . n 
A 1 173 ASP 173 173 173 ASP ASP A . n 
A 1 174 VAL 174 174 174 VAL VAL A . n 
A 1 175 ASN 175 175 175 ASN ASN A . n 
A 1 176 PRO 176 176 176 PRO PRO A . n 
A 1 177 GLN 177 177 177 GLN GLN A . n 
A 1 178 ALA 178 178 178 ALA ALA A . n 
A 1 179 VAL 179 179 179 VAL VAL A . n 
A 1 180 VAL 180 180 180 VAL VAL A . n 
A 1 181 ASP 181 181 181 ASP ASP A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 MET 183 183 183 MET MET A . n 
A 1 184 GLU 184 184 184 GLU GLU A . n 
A 1 185 ARG 185 185 185 ARG ARG A . n 
A 1 186 HIS 186 186 186 HIS HIS A . n 
A 1 187 HIS 187 187 187 HIS HIS A . n 
A 1 188 VAL 188 188 188 VAL VAL A . n 
A 1 189 GLN 189 189 189 GLN GLN A . n 
A 1 190 TRP 190 190 190 TRP TRP A . n 
A 1 191 LEU 191 191 191 LEU LEU A . n 
A 1 192 ILE 192 192 192 ILE ILE A . n 
A 1 193 HIS 193 193 193 HIS HIS A . n 
A 1 194 GLY 194 194 194 GLY GLY A . n 
A 1 195 HIS 195 195 195 HIS HIS A . n 
A 1 196 THR 196 196 196 THR THR A . n 
A 1 197 HIS 197 197 197 HIS HIS A . n 
A 1 198 ARG 198 198 198 ARG ARG A . n 
A 1 199 PRO 199 199 199 PRO PRO A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 VAL 201 201 201 VAL VAL A . n 
A 1 202 HIS 202 202 202 HIS HIS A . n 
A 1 203 GLU 203 203 203 GLU GLU A . n 
A 1 204 LEU 204 204 204 LEU LEU A . n 
A 1 205 GLN 205 205 205 GLN GLN A . n 
A 1 206 ALA 206 206 206 ALA ALA A . n 
A 1 207 ASN 207 207 207 ASN ASN A . n 
A 1 208 GLY 208 208 208 GLY GLY A . n 
A 1 209 GLN 209 209 209 GLN GLN A . n 
A 1 210 PRO 210 210 210 PRO PRO A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 TRP 212 212 212 TRP TRP A . n 
A 1 213 ARG 213 213 213 ARG ARG A . n 
A 1 214 VAL 214 214 214 VAL VAL A . n 
A 1 215 VAL 215 215 215 VAL VAL A . n 
A 1 216 LEU 216 216 216 LEU LEU A . n 
A 1 217 GLY 217 217 217 GLY GLY A . n 
A 1 218 ALA 218 218 218 ALA ALA A . n 
A 1 219 TRP 219 219 219 TRP TRP A . n 
A 1 220 HIS 220 220 220 HIS HIS A . n 
A 1 221 SER 221 221 221 SER SER A . n 
A 1 222 GLU 222 222 222 GLU GLU A . n 
A 1 223 GLY 223 223 223 GLY GLY A . n 
A 1 224 SER 224 224 224 SER SER A . n 
A 1 225 MET 225 225 225 MET MET A . n 
A 1 226 VAL 226 226 226 VAL VAL A . n 
A 1 227 LYS 227 227 227 LYS LYS A . n 
A 1 228 VAL 228 228 228 VAL VAL A . n 
A 1 229 THR 229 229 229 THR THR A . n 
A 1 230 PRO 230 230 230 PRO PRO A . n 
A 1 231 ASP 231 231 231 ASP ASP A . n 
A 1 232 ASP 232 232 232 ASP ASP A . n 
A 1 233 VAL 233 233 233 VAL VAL A . n 
A 1 234 GLU 234 234 234 GLU GLU A . n 
A 1 235 LEU 235 235 235 LEU LEU A . n 
A 1 236 ILE 236 236 236 ILE ILE A . n 
A 1 237 HIS 237 237 237 HIS HIS A . n 
A 1 238 PHE 238 238 238 PHE PHE A . n 
A 1 239 PRO 239 239 239 PRO PRO A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 LEU 241 241 241 LEU LEU A . n 
A 1 242 GLU 242 242 242 GLU GLU A . n 
A 1 243 GLU 243 243 243 GLU GLU A . n 
A 1 244 ASN 244 244 244 ASN ASN A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 TYR 246 246 246 TYR TYR A . n 
A 1 247 PHE 247 247 247 PHE PHE A . n 
A 1 248 GLN 248 248 ?   ?   ?   A . n 
A 1 249 SER 249 249 ?   ?   ?   A . n 
A 1 250 HIS 250 250 250 HIS HIS A . n 
A 1 251 HIS 251 251 251 HIS HIS A . n 
A 1 252 HIS 252 252 252 HIS HIS A . n 
A 1 253 HIS 253 253 ?   ?   ?   A . n 
A 1 254 HIS 254 254 ?   ?   ?   A . n 
A 1 255 HIS 255 255 ?   ?   ?   A . n 
A 1 256 HIS 256 256 ?   ?   ?   A . n 
A 1 257 HIS 257 257 ?   ?   ?   A . n 
A 1 258 HIS 258 258 ?   ?   ?   A . n 
A 1 259 HIS 259 259 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1AVY 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1AVY 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 A1AVY 1  301 301 A1AVY LIG A . 
C 3 MN    1  302 1   MN    MN  A . 
D 3 MN    1  303 2   MN    MN  A . 
E 4 HOH   1  401 53  HOH   HOH A . 
E 4 HOH   2  402 6   HOH   HOH A . 
E 4 HOH   3  403 38  HOH   HOH A . 
E 4 HOH   4  404 29  HOH   HOH A . 
E 4 HOH   5  405 7   HOH   HOH A . 
E 4 HOH   6  406 19  HOH   HOH A . 
E 4 HOH   7  407 76  HOH   HOH A . 
E 4 HOH   8  408 64  HOH   HOH A . 
E 4 HOH   9  409 4   HOH   HOH A . 
E 4 HOH   10 410 39  HOH   HOH A . 
E 4 HOH   11 411 5   HOH   HOH A . 
E 4 HOH   12 412 17  HOH   HOH A . 
E 4 HOH   13 413 40  HOH   HOH A . 
E 4 HOH   14 414 37  HOH   HOH A . 
E 4 HOH   15 415 33  HOH   HOH A . 
E 4 HOH   16 416 43  HOH   HOH A . 
E 4 HOH   17 417 42  HOH   HOH A . 
E 4 HOH   18 418 14  HOH   HOH A . 
E 4 HOH   19 419 32  HOH   HOH A . 
E 4 HOH   20 420 2   HOH   HOH A . 
E 4 HOH   21 421 16  HOH   HOH A . 
E 4 HOH   22 422 28  HOH   HOH A . 
E 4 HOH   23 423 75  HOH   HOH A . 
E 4 HOH   24 424 21  HOH   HOH A . 
E 4 HOH   25 425 27  HOH   HOH A . 
E 4 HOH   26 426 46  HOH   HOH A . 
E 4 HOH   27 427 30  HOH   HOH A . 
E 4 HOH   28 428 10  HOH   HOH A . 
E 4 HOH   29 429 3   HOH   HOH A . 
E 4 HOH   30 430 1   HOH   HOH A . 
E 4 HOH   31 431 24  HOH   HOH A . 
E 4 HOH   32 432 18  HOH   HOH A . 
E 4 HOH   33 433 9   HOH   HOH A . 
E 4 HOH   34 434 8   HOH   HOH A . 
E 4 HOH   35 435 31  HOH   HOH A . 
E 4 HOH   36 436 25  HOH   HOH A . 
E 4 HOH   37 437 20  HOH   HOH A . 
E 4 HOH   38 438 22  HOH   HOH A . 
E 4 HOH   39 439 41  HOH   HOH A . 
E 4 HOH   40 440 62  HOH   HOH A . 
E 4 HOH   41 441 12  HOH   HOH A . 
E 4 HOH   42 442 79  HOH   HOH A . 
E 4 HOH   43 443 66  HOH   HOH A . 
E 4 HOH   44 444 84  HOH   HOH A . 
E 4 HOH   45 445 56  HOH   HOH A . 
E 4 HOH   46 446 48  HOH   HOH A . 
E 4 HOH   47 447 60  HOH   HOH A . 
E 4 HOH   48 448 54  HOH   HOH A . 
E 4 HOH   49 449 44  HOH   HOH A . 
E 4 HOH   50 450 13  HOH   HOH A . 
E 4 HOH   51 451 36  HOH   HOH A . 
E 4 HOH   52 452 59  HOH   HOH A . 
E 4 HOH   53 453 61  HOH   HOH A . 
E 4 HOH   54 454 67  HOH   HOH A . 
E 4 HOH   55 455 74  HOH   HOH A . 
E 4 HOH   56 456 15  HOH   HOH A . 
E 4 HOH   57 457 57  HOH   HOH A . 
E 4 HOH   58 458 26  HOH   HOH A . 
E 4 HOH   59 459 23  HOH   HOH A . 
E 4 HOH   60 460 35  HOH   HOH A . 
E 4 HOH   61 461 11  HOH   HOH A . 
E 4 HOH   62 462 50  HOH   HOH A . 
E 4 HOH   63 463 81  HOH   HOH A . 
E 4 HOH   64 464 65  HOH   HOH A . 
E 4 HOH   65 465 49  HOH   HOH A . 
E 4 HOH   66 466 34  HOH   HOH A . 
E 4 HOH   67 467 45  HOH   HOH A . 
E 4 HOH   68 468 58  HOH   HOH A . 
E 4 HOH   69 469 52  HOH   HOH A . 
E 4 HOH   70 470 85  HOH   HOH A . 
E 4 HOH   71 471 87  HOH   HOH A . 
E 4 HOH   72 472 88  HOH   HOH A . 
E 4 HOH   73 473 72  HOH   HOH A . 
E 4 HOH   74 474 47  HOH   HOH A . 
E 4 HOH   75 475 83  HOH   HOH A . 
E 4 HOH   76 476 82  HOH   HOH A . 
E 4 HOH   77 477 68  HOH   HOH A . 
E 4 HOH   78 478 63  HOH   HOH A . 
E 4 HOH   79 479 78  HOH   HOH A . 
E 4 HOH   80 480 86  HOH   HOH A . 
E 4 HOH   81 481 80  HOH   HOH A . 
E 4 HOH   82 482 69  HOH   HOH A . 
E 4 HOH   83 483 51  HOH   HOH A . 
E 4 HOH   84 484 73  HOH   HOH A . 
E 4 HOH   85 485 70  HOH   HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLN 27  ? CD  ? A GLN 27  CD  
2  1 Y 1 A GLN 27  ? OE1 ? A GLN 27  OE1 
3  1 Y 1 A GLN 27  ? NE2 ? A GLN 27  NE2 
4  1 Y 1 A GLU 109 ? CD  ? A GLU 109 CD  
5  1 Y 1 A GLU 109 ? OE1 ? A GLU 109 OE1 
6  1 Y 1 A GLU 109 ? OE2 ? A GLU 109 OE2 
7  1 Y 1 A LYS 161 ? CG  ? A LYS 161 CG  
8  1 Y 1 A LYS 161 ? CD  ? A LYS 161 CD  
9  1 Y 1 A LYS 161 ? CE  ? A LYS 161 CE  
10 1 Y 1 A LYS 161 ? NZ  ? A LYS 161 NZ  
11 1 Y 1 A GLU 170 ? CG  ? A GLU 170 CG  
12 1 Y 1 A GLU 170 ? CD  ? A GLU 170 CD  
13 1 Y 1 A GLU 170 ? OE1 ? A GLU 170 OE1 
14 1 Y 1 A GLU 170 ? OE2 ? A GLU 170 OE2 
15 1 Y 1 A GLN 177 ? CG  ? A GLN 177 CG  
16 1 Y 1 A GLN 177 ? CD  ? A GLN 177 CD  
17 1 Y 1 A GLN 177 ? OE1 ? A GLN 177 OE1 
18 1 Y 1 A GLN 177 ? NE2 ? A GLN 177 NE2 
19 1 Y 1 A GLU 242 ? CG  ? A GLU 242 CG  
20 1 Y 1 A GLU 242 ? CD  ? A GLU 242 CD  
21 1 Y 1 A GLU 242 ? OE1 ? A GLU 242 OE1 
22 1 Y 1 A GLU 242 ? OE2 ? A GLU 242 OE2 
23 1 Y 1 A LEU 245 ? CD1 ? A LEU 245 CD1 
24 1 Y 1 A LEU 245 ? CD2 ? A LEU 245 CD2 
25 1 Y 1 A HIS 252 ? CG  ? A HIS 252 CG  
26 1 Y 1 A HIS 252 ? ND1 ? A HIS 252 ND1 
27 1 Y 1 A HIS 252 ? CD2 ? A HIS 252 CD2 
28 1 Y 1 A HIS 252 ? CE1 ? A HIS 252 CE1 
29 1 Y 1 A HIS 252 ? NE2 ? A HIS 252 NE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XSCALE ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CCY 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     105.710 
_cell.length_a_esd                 ? 
_cell.length_b                     105.710 
_cell.length_b_esd                 ? 
_cell.length_c                     53.560 
_cell.length_c_esd                 ? 
_cell.volume                       518326.419 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CCY 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            
;P 32 2"
;
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CCY 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.92 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          57.82 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;1.2 mg/mL of LpxH, 
0.16 mM LPH-90, 
10 mM MES (pH 6.0), 
100 mM NaCl, 
0.5 mM DTT, 
2.5% glycerol, 
0.8% DMSO, 
0.05 M HEPES pH 7.0, 
and 18 % w/v PEG 400
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-07-13 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.953738 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'DIAMOND BEAMLINE I04' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.953738 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   I04 
_diffrn_source.pdbx_synchrotron_site       Diamond 
# 
_reflns.B_iso_Wilson_estimate                          38.47 
_reflns.entry_id                                       9CCY 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.05 
_reflns.d_resolution_low                               45.77 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     21766 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.29 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                20.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          22.75 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1.000 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.05 
_reflns_shell.d_res_low                                     2.123 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2159 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.918 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               43.99 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9CCY 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.05 
_refine.ls_d_res_low                             45.77 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     21762 
_refine.ls_number_reflns_R_free                  1089 
_refine.ls_number_reflns_R_work                  20673 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.31 
_refine.ls_percent_reflns_R_free                 5.00 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1858 
_refine.ls_R_factor_R_free                       0.2087 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1846 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.37 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 20.7535 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1856 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.05 
_refine_hist.d_res_low                        45.77 
_refine_hist.number_atoms_solvent             85 
_refine_hist.number_atoms_total               2038 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1920 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         33 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0039  ? 2025 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.6350  ? 2761 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0467  ? 294  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0055  ? 358  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 10.7183 ? 306  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.05 2.14  . . 135 2569 99.89  . . . . 0.1987 . . . . . . . . . . . 0.2559 
'X-RAY DIFFRACTION' 2.14 2.26  . . 136 2563 99.89  . . . . 0.1934 . . . . . . . . . . . 0.2047 
'X-RAY DIFFRACTION' 2.26 2.40  . . 134 2562 99.96  . . . . 0.1748 . . . . . . . . . . . 0.2311 
'X-RAY DIFFRACTION' 2.40 2.58  . . 137 2596 100.00 . . . . 0.1871 . . . . . . . . . . . 0.2222 
'X-RAY DIFFRACTION' 2.58 2.84  . . 136 2588 99.96  . . . . 0.1926 . . . . . . . . . . . 0.2296 
'X-RAY DIFFRACTION' 2.84 3.25  . . 137 2592 100.00 . . . . 0.1908 . . . . . . . . . . . 0.1961 
'X-RAY DIFFRACTION' 3.25 4.10  . . 131 2501 94.95  . . . . 0.1741 . . . . . . . . . . . 0.2154 
'X-RAY DIFFRACTION' 4.10 45.77 . . 143 2702 99.96  . . . . 0.1857 . . . . . . . . . . . 0.1944 
# 
_struct.entry_id                     9CCY 
_struct.title                        'Crystal structure of the Klebsiella pneumoniae LpxH / JH-LPH-90 complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CCY 
_struct_keywords.text            'LpxH, lipid A, antibiotic, inhibitor' 
_struct_keywords.pdbx_keywords   ANTIBIOTIC 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A1S0WIC1_KLEPN 
_struct_ref.pdbx_db_accession          A0A1S0WIC1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MATLFIADLHLQTEEPAITAGFLRFLQGEARQADALYILGDLFEAWIGDDDPNPLHQQIASAIKAVVDAGVPCYFIHGNR
DFLVGQRFARQSGMILLAEEERLDLYGREVLIMHGDTLCTDDQGYLAFRAKVHTPWIQRLFLALPLFIRHRIAARMRADS
KAANSSKSMEIMDVNPQAVVDAMERHHVQWLIHGHTHRPAVHELQANGQPAWRVVLGAWHSEGSMVKVTPDDVELIHFPF

;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9CCY 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 240 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A1S0WIC1 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  240 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       240 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9CCY LEU A 241 ? UNP A0A1S0WIC1 ? ? 'expression tag' 241 1  
1 9CCY GLU A 242 ? UNP A0A1S0WIC1 ? ? 'expression tag' 242 2  
1 9CCY GLU A 243 ? UNP A0A1S0WIC1 ? ? 'expression tag' 243 3  
1 9CCY ASN A 244 ? UNP A0A1S0WIC1 ? ? 'expression tag' 244 4  
1 9CCY LEU A 245 ? UNP A0A1S0WIC1 ? ? 'expression tag' 245 5  
1 9CCY TYR A 246 ? UNP A0A1S0WIC1 ? ? 'expression tag' 246 6  
1 9CCY PHE A 247 ? UNP A0A1S0WIC1 ? ? 'expression tag' 247 7  
1 9CCY GLN A 248 ? UNP A0A1S0WIC1 ? ? 'expression tag' 248 8  
1 9CCY SER A 249 ? UNP A0A1S0WIC1 ? ? 'expression tag' 249 9  
1 9CCY HIS A 250 ? UNP A0A1S0WIC1 ? ? 'expression tag' 250 10 
1 9CCY HIS A 251 ? UNP A0A1S0WIC1 ? ? 'expression tag' 251 11 
1 9CCY HIS A 252 ? UNP A0A1S0WIC1 ? ? 'expression tag' 252 12 
1 9CCY HIS A 253 ? UNP A0A1S0WIC1 ? ? 'expression tag' 253 13 
1 9CCY HIS A 254 ? UNP A0A1S0WIC1 ? ? 'expression tag' 254 14 
1 9CCY HIS A 255 ? UNP A0A1S0WIC1 ? ? 'expression tag' 255 15 
1 9CCY HIS A 256 ? UNP A0A1S0WIC1 ? ? 'expression tag' 256 16 
1 9CCY HIS A 257 ? UNP A0A1S0WIC1 ? ? 'expression tag' 257 17 
1 9CCY HIS A 258 ? UNP A0A1S0WIC1 ? ? 'expression tag' 258 18 
1 9CCY HIS A 259 ? UNP A0A1S0WIC1 ? ? 'expression tag' 259 19 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 GLU A 15  ? GLY A 28  ? GLU A 15  GLY A 28  1 ? 14 
HELX_P HELX_P2 AA2 GLU A 29  ? ALA A 33  ? GLU A 29  ALA A 33  5 ? 5  
HELX_P HELX_P3 AA3 ASN A 53  ? ALA A 69  ? ASN A 53  ALA A 69  1 ? 17 
HELX_P HELX_P4 AA4 GLY A 85  ? GLY A 93  ? GLY A 85  GLY A 93  1 ? 9  
HELX_P HELX_P5 AA5 GLY A 115 ? CYS A 119 ? GLY A 115 CYS A 119 5 ? 5  
HELX_P HELX_P6 AA6 ASP A 122 ? HIS A 133 ? ASP A 122 HIS A 133 1 ? 12 
HELX_P HELX_P7 AA7 THR A 134 ? LEU A 144 ? THR A 134 LEU A 144 1 ? 11 
HELX_P HELX_P8 AA8 PRO A 145 ? ALA A 162 ? PRO A 145 ALA A 162 1 ? 18 
HELX_P HELX_P9 AA9 ASN A 175 ? HIS A 186 ? ASN A 175 HIS A 186 1 ? 12 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A ASP 8   OD1 ? ? ? 1_555 C MN . MN ? ? A ASP 8   A MN 302 1_555 ? ? ? ? ? ? ? 2.232 ? ? 
metalc2 metalc ? ? A HIS 10  NE2 ? ? ? 1_555 C MN . MN ? ? A HIS 10  A MN 302 1_555 ? ? ? ? ? ? ? 2.439 ? ? 
metalc3 metalc ? ? A ASP 41  OD2 ? ? ? 1_555 C MN . MN ? ? A ASP 41  A MN 302 1_555 ? ? ? ? ? ? ? 2.698 ? ? 
metalc4 metalc ? ? A ASP 41  OD2 ? ? ? 1_555 D MN . MN ? ? A ASP 41  A MN 303 1_555 ? ? ? ? ? ? ? 2.619 ? ? 
metalc5 metalc ? ? A ASN 79  OD1 ? ? ? 1_555 D MN . MN ? ? A ASN 79  A MN 303 1_555 ? ? ? ? ? ? ? 2.042 ? ? 
metalc6 metalc ? ? A HIS 114 NE2 ? ? ? 1_555 D MN . MN ? ? A HIS 114 A MN 303 1_555 ? ? ? ? ? ? ? 2.314 ? ? 
metalc7 metalc ? ? A HIS 195 ND1 ? ? ? 1_555 D MN . MN ? ? A HIS 195 A MN 303 1_555 ? ? ? ? ? ? ? 2.023 ? ? 
metalc8 metalc ? ? A HIS 197 NE2 ? ? ? 1_555 C MN . MN ? ? A HIS 197 A MN 302 1_555 ? ? ? ? ? ? ? 2.557 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD1 ? A ASP 8   ? A ASP 8   ? 1_555 MN ? C MN . ? A MN 302 ? 1_555 NE2 ? A HIS 10  ? A HIS 10  ? 1_555 109.3 ? 
2  OD1 ? A ASP 8   ? A ASP 8   ? 1_555 MN ? C MN . ? A MN 302 ? 1_555 OD2 ? A ASP 41  ? A ASP 41  ? 1_555 80.1  ? 
3  NE2 ? A HIS 10  ? A HIS 10  ? 1_555 MN ? C MN . ? A MN 302 ? 1_555 OD2 ? A ASP 41  ? A ASP 41  ? 1_555 98.9  ? 
4  OD1 ? A ASP 8   ? A ASP 8   ? 1_555 MN ? C MN . ? A MN 302 ? 1_555 NE2 ? A HIS 197 ? A HIS 197 ? 1_555 110.2 ? 
5  NE2 ? A HIS 10  ? A HIS 10  ? 1_555 MN ? C MN . ? A MN 302 ? 1_555 NE2 ? A HIS 197 ? A HIS 197 ? 1_555 79.3  ? 
6  OD2 ? A ASP 41  ? A ASP 41  ? 1_555 MN ? C MN . ? A MN 302 ? 1_555 NE2 ? A HIS 197 ? A HIS 197 ? 1_555 169.6 ? 
7  OD2 ? A ASP 41  ? A ASP 41  ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 OD1 ? A ASN 79  ? A ASN 79  ? 1_555 71.4  ? 
8  OD2 ? A ASP 41  ? A ASP 41  ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 NE2 ? A HIS 114 ? A HIS 114 ? 1_555 92.2  ? 
9  OD1 ? A ASN 79  ? A ASN 79  ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 NE2 ? A HIS 114 ? A HIS 114 ? 1_555 92.5  ? 
10 OD2 ? A ASP 41  ? A ASP 41  ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 ND1 ? A HIS 195 ? A HIS 195 ? 1_555 171.9 ? 
11 OD1 ? A ASN 79  ? A ASN 79  ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 ND1 ? A HIS 195 ? A HIS 195 ? 1_555 106.8 ? 
12 NE2 ? A HIS 114 ? A HIS 114 ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 ND1 ? A HIS 195 ? A HIS 195 ? 1_555 95.8  ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? parallel      
AA2 3 4 ? parallel      
AA2 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 95  ? LEU A 96  ? ILE A 95  LEU A 96  
AA1 2 CYS A 73  ? PHE A 75  ? CYS A 73  PHE A 75  
AA1 3 ALA A 35  ? ILE A 38  ? ALA A 35  ILE A 38  
AA1 4 THR A 3   ? ILE A 6   ? THR A 3   ILE A 6   
AA1 5 GLY A 223 ? VAL A 228 ? GLY A 223 VAL A 228 
AA1 6 VAL A 233 ? PHE A 238 ? VAL A 233 PHE A 238 
AA2 1 GLU A 100 ? LEU A 105 ? GLU A 100 LEU A 105 
AA2 2 ARG A 108 ? MET A 113 ? ARG A 108 MET A 113 
AA2 3 TRP A 190 ? HIS A 193 ? TRP A 190 HIS A 193 
AA2 4 GLN A 209 ? VAL A 215 ? GLN A 209 VAL A 215 
AA2 5 ALA A 200 ? ALA A 206 ? ALA A 200 ALA A 206 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ILE A 95  ? O ILE A 95  N PHE A 75  ? N PHE A 75  
AA1 2 3 O TYR A 74  ? O TYR A 74  N ILE A 38  ? N ILE A 38  
AA1 3 4 O ALA A 35  ? O ALA A 35  N LEU A 4   ? N LEU A 4   
AA1 4 5 N THR A 3   ? N THR A 3   O VAL A 228 ? O VAL A 228 
AA1 5 6 N GLY A 223 ? N GLY A 223 O PHE A 238 ? O PHE A 238 
AA2 1 2 N LEU A 103 ? N LEU A 103 O VAL A 110 ? O VAL A 110 
AA2 2 3 N LEU A 111 ? N LEU A 111 O TRP A 190 ? O TRP A 190 
AA2 3 4 N LEU A 191 ? N LEU A 191 O VAL A 214 ? O VAL A 214 
AA2 4 5 O ALA A 211 ? O ALA A 211 N LEU A 204 ? N LEU A 204 
# 
_pdbx_entry_details.entry_id                   9CCY 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LEU A 39  ? ? -90.99 48.40  
2 1 CYS A 119 ? ? -93.75 59.63  
3 1 HIS A 195 ? ? 73.12  -48.09 
4 1 HIS A 220 ? ? -92.00 -68.23 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+2/3   
3 -x+y,-x,z+1/3  
4 x-y,-y,-z+1/3  
5 -x,-x+y,-z+2/3 
6 y,x,-z         
# 
loop_
_pdbx_refine_tls.id 
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[1][1]_esd 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][2]_esd 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[1][3]_esd 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[2][2]_esd 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.T[2][3]_esd 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[3][3]_esd 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[1][1]_esd 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][2]_esd 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[1][3]_esd 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[2][2]_esd 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.L[2][3]_esd 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[3][3]_esd 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][1]_esd 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][2]_esd 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[1][3]_esd 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][1]_esd 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][2]_esd 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][3]_esd 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][1]_esd 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][2]_esd 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[3][3]_esd 
1 'X-RAY DIFFRACTION' ? refined -36.3525615033 -30.8847221423 -1.04164616212 0.370725664841 ? 0.00990289447189 ? -0.0215584848286 
? 0.352003392782 ? -0.0269503218649 ? 0.334746016762 ? 1.719296033    ? -0.414247754451 ? 0.343906350509  ? 1.93961494584 ? 
-1.56109998598  ? 2.52477801294  ? 0.0291242690483  ? 0.147595795706   ? -0.154916949088  ? -0.399835500378  ? -0.177760440004   ? 
-0.153977876939 ? 0.284567472135     ? 0.07934140582    ? 0.13023592438    ? 
2 'X-RAY DIFFRACTION' ? refined -42.1860294773 -23.3577118164 4.0206210601   0.339620310368 ? 0.00883817935684 ? -0.0132204638455 
? 0.335493455049 ? -0.0216722158475 ? 0.337024153037 ? 1.03559763449  ? -1.05803802188  ? 0.0217592852389 ? 1.32023650401 ? 
-0.197012943066 ? 0.586617613877 ? -0.0279377548581 ? -0.105335361525  ? 0.11293945788    ? 0.00733804739846 ? 0.0446758441676   ? 
0.0102526448721 ? -0.0867535947579   ? -0.0202971376158 ? -0.0172352933882 ? 
3 'X-RAY DIFFRACTION' ? refined -32.1395686954 -25.8020051254 12.8346074888  0.355165867584 ? 0.0156747086087  ? -0.0112805538296 
? 0.411855547486 ? -0.0248915355626 ? 0.333099288806 ? 1.92337223821  ? 0.318274913606  ? -0.356556179685 ? 1.47534656379 ? 
-0.444344418644 ? 1.42653506043  ? -0.0414537878614 ? -0.351234931114  ? 0.0927497600313  ? 0.264361677791   ? 0.00411813614801  ? 
-0.137416326375 ? -0.000202183881835 ? 0.187555186426   ? 0.0428725383306  ? 
4 'X-RAY DIFFRACTION' ? refined -37.0643935657 -6.93497831659 11.4919931968  0.438717219245 ? 0.0302401478783  ? -0.0769017879103 
? 0.414539286084 ? -0.12459132829   ? 0.534845954401 ? 2.45610493604  ? -0.86353794226  ? 0.205598363767  ? 1.80499683532 ? 
0.571754481216  ? 1.64943687541  ? -0.287441489936  ? -0.683969809824  ? 0.581960740655   ? 0.442994511136   ? 0.277628018793    ? 
-0.55254592875  ? 0.0470247538587    ? 0.140019470523   ? 0.0186557724709  ? 
5 'X-RAY DIFFRACTION' ? refined -41.0156813738 -5.02989385667 -1.49518467578 0.596345399457 ? 0.0264427144581  ? 0.0154567761042  
? 0.383245958287 ? -0.0525063598727 ? 0.474612063428 ? 5.09773053555  ? 0.386817133251  ? -1.08950705296  ? 4.2625492867  ? 
-0.249444392851 ? 3.93230557866  ? -0.0349062456504 ? 0.493103693736   ? -0.0603182672846 ? -1.10822687303   ? -0.143234475392   ? 
-0.258737243608 ? -0.167565728237    ? 0.301782753639   ? 0.143608678019   ? 
6 'X-RAY DIFFRACTION' ? refined -18.5082559586 -18.5268466419 12.0041168749  0.367126046701 ? -0.0322430148497 ? -0.0607670467821 
? 0.509908788997 ? -0.0506743899214 ? 0.50193640066  ? 3.23184096748  ? -1.76657488357  ? 0.537797139833  ? 4.69425427896 ? 
-0.137781992232 ? 0.137947129649 ? -0.272184198624  ? -0.411602027326  ? 0.627244603405   ? 0.512509699952   ? -0.0297134923295  ? 
-0.963690214547 ? -0.282060749781    ? 0.0888286887383  ? 0.205485542009   ? 
7 'X-RAY DIFFRACTION' ? refined -20.814777744  -28.4943010207 7.26768958545  0.319584775578 ? 0.0356090303963  ? -0.0581057183469 
? 0.379637412388 ? -0.0185550483615 ? 0.412837484274 ? 2.26621712447  ? 0.282560659033  ? -0.800820124229 ? 1.89422366683 ? 
0.721671090682  ? 1.7099684354   ? 0.0243166935921  ? -0.0479010058047 ? 0.110171890026   ? 0.0441808245168  ? -0.00712997795624 ? 
-0.456044227144 ? 0.0656025328286    ? 0.13065134077    ? 0.00277772486207 ? 
8 'X-RAY DIFFRACTION' ? refined -26.5882811219 -38.8932249162 -10.4007109906 0.480489208248 ? 0.0752458219408  ? -0.0473090022569 
? 0.471085811109 ? -0.0185248531455 ? 0.434653816226 ? 0.649013336435 ? -0.363689623577 ? -0.245303348178 ? 1.23008539544 ? 
1.27604411927   ? 1.30000115285  ? 0.151109313971   ? 0.300952974842   ? -0.0932828063978 ? -0.453537159571  ? -0.200763089887   ? 
0.207834369275  ? 0.00408745031354   ? -0.0335999082031 ? 0.00805339354487 ? 
# 
loop_
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_PDB_ins_code 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_PDB_ins_code 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
1 'X-RAY DIFFRACTION' 1 A 1   A 2   ? A 37  A 38  ? ? 
;chain 'A' and (resid 2 through 38 )
;
2 'X-RAY DIFFRACTION' 2 A 38  A 39  ? A 84  A 85  ? ? 
;chain 'A' and (resid 39 through 85 )
;
3 'X-RAY DIFFRACTION' 3 A 85  A 86  ? A 121 A 122 ? ? 
;chain 'A' and (resid 86 through 122 )
;
4 'X-RAY DIFFRACTION' 4 A 122 A 123 ? A 144 A 145 ? ? 
;chain 'A' and (resid 123 through 145 )
;
5 'X-RAY DIFFRACTION' 5 A 145 A 146 ? A 160 A 161 ? ? 
;chain 'A' and (resid 146 through 161 )
;
6 'X-RAY DIFFRACTION' 6 A 161 A 162 ? A 177 A 185 ? ? 
;chain 'A' and (resid 162 through 185 )
;
7 'X-RAY DIFFRACTION' 7 A 178 A 186 ? A 220 A 228 ? ? 
;chain 'A' and (resid 186 through 228 )
;
8 'X-RAY DIFFRACTION' 8 A 221 A 229 ? A 242 A 252 ? ? 
;chain 'A' and (resid 229 through 252 )
;
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A ALA 163 ? A ALA 163 
3  1 Y 1 A ASN 164 ? A ASN 164 
4  1 Y 1 A SER 165 ? A SER 165 
5  1 Y 1 A SER 166 ? A SER 166 
6  1 Y 1 A LYS 167 ? A LYS 167 
7  1 Y 1 A SER 168 ? A SER 168 
8  1 Y 1 A MET 169 ? A MET 169 
9  1 Y 1 A GLN 248 ? A GLN 248 
10 1 Y 1 A SER 249 ? A SER 249 
11 1 Y 1 A HIS 253 ? A HIS 253 
12 1 Y 1 A HIS 254 ? A HIS 254 
13 1 Y 1 A HIS 255 ? A HIS 255 
14 1 Y 1 A HIS 256 ? A HIS 256 
15 1 Y 1 A HIS 257 ? A HIS 257 
16 1 Y 1 A HIS 258 ? A HIS 258 
17 1 Y 1 A HIS 259 ? A HIS 259 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1AVY C13  C  N N 1   
A1AVY C15  C  N N 2   
A1AVY C20  C  Y N 3   
A1AVY C21  C  Y N 4   
A1AVY C22  C  Y N 5   
A1AVY C24  C  Y N 6   
A1AVY C26  C  N N 7   
A1AVY C01  C  Y N 8   
A1AVY C02  C  Y N 9   
A1AVY C04  C  Y N 10  
A1AVY C05  C  Y N 11  
A1AVY C06  C  Y N 12  
A1AVY C07  C  N N 13  
A1AVY C12  C  N N 14  
A1AVY C16  C  N N 15  
A1AVY C23  C  Y N 16  
A1AVY C25  C  Y N 17  
A1AVY C27  C  N N 18  
A1AVY C29  C  N N 19  
A1AVY C31  C  N N 20  
A1AVY F08  F  N N 21  
A1AVY F09  F  N N 22  
A1AVY F10  F  N N 23  
A1AVY N03  N  Y N 24  
A1AVY N11  N  N N 25  
A1AVY N14  N  N N 26  
A1AVY N28  N  N N 27  
A1AVY O18  O  N N 28  
A1AVY O19  O  N N 29  
A1AVY O30  O  N N 30  
A1AVY S17  S  N N 31  
A1AVY H131 H  N N 32  
A1AVY H132 H  N N 33  
A1AVY H152 H  N N 34  
A1AVY H151 H  N N 35  
A1AVY H211 H  N N 36  
A1AVY H221 H  N N 37  
A1AVY H262 H  N N 38  
A1AVY H261 H  N N 39  
A1AVY H011 H  N N 40  
A1AVY H051 H  N N 41  
A1AVY H061 H  N N 42  
A1AVY H121 H  N N 43  
A1AVY H122 H  N N 44  
A1AVY H161 H  N N 45  
A1AVY H162 H  N N 46  
A1AVY H251 H  N N 47  
A1AVY H272 H  N N 48  
A1AVY H271 H  N N 49  
A1AVY H312 H  N N 50  
A1AVY H311 H  N N 51  
A1AVY H313 H  N N 52  
ALA   N    N  N N 53  
ALA   CA   C  N S 54  
ALA   C    C  N N 55  
ALA   O    O  N N 56  
ALA   CB   C  N N 57  
ALA   OXT  O  N N 58  
ALA   H    H  N N 59  
ALA   H2   H  N N 60  
ALA   HA   H  N N 61  
ALA   HB1  H  N N 62  
ALA   HB2  H  N N 63  
ALA   HB3  H  N N 64  
ALA   HXT  H  N N 65  
ARG   N    N  N N 66  
ARG   CA   C  N S 67  
ARG   C    C  N N 68  
ARG   O    O  N N 69  
ARG   CB   C  N N 70  
ARG   CG   C  N N 71  
ARG   CD   C  N N 72  
ARG   NE   N  N N 73  
ARG   CZ   C  N N 74  
ARG   NH1  N  N N 75  
ARG   NH2  N  N N 76  
ARG   OXT  O  N N 77  
ARG   H    H  N N 78  
ARG   H2   H  N N 79  
ARG   HA   H  N N 80  
ARG   HB2  H  N N 81  
ARG   HB3  H  N N 82  
ARG   HG2  H  N N 83  
ARG   HG3  H  N N 84  
ARG   HD2  H  N N 85  
ARG   HD3  H  N N 86  
ARG   HE   H  N N 87  
ARG   HH11 H  N N 88  
ARG   HH12 H  N N 89  
ARG   HH21 H  N N 90  
ARG   HH22 H  N N 91  
ARG   HXT  H  N N 92  
ASN   N    N  N N 93  
ASN   CA   C  N S 94  
ASN   C    C  N N 95  
ASN   O    O  N N 96  
ASN   CB   C  N N 97  
ASN   CG   C  N N 98  
ASN   OD1  O  N N 99  
ASN   ND2  N  N N 100 
ASN   OXT  O  N N 101 
ASN   H    H  N N 102 
ASN   H2   H  N N 103 
ASN   HA   H  N N 104 
ASN   HB2  H  N N 105 
ASN   HB3  H  N N 106 
ASN   HD21 H  N N 107 
ASN   HD22 H  N N 108 
ASN   HXT  H  N N 109 
ASP   N    N  N N 110 
ASP   CA   C  N S 111 
ASP   C    C  N N 112 
ASP   O    O  N N 113 
ASP   CB   C  N N 114 
ASP   CG   C  N N 115 
ASP   OD1  O  N N 116 
ASP   OD2  O  N N 117 
ASP   OXT  O  N N 118 
ASP   H    H  N N 119 
ASP   H2   H  N N 120 
ASP   HA   H  N N 121 
ASP   HB2  H  N N 122 
ASP   HB3  H  N N 123 
ASP   HD2  H  N N 124 
ASP   HXT  H  N N 125 
CYS   N    N  N N 126 
CYS   CA   C  N R 127 
CYS   C    C  N N 128 
CYS   O    O  N N 129 
CYS   CB   C  N N 130 
CYS   SG   S  N N 131 
CYS   OXT  O  N N 132 
CYS   H    H  N N 133 
CYS   H2   H  N N 134 
CYS   HA   H  N N 135 
CYS   HB2  H  N N 136 
CYS   HB3  H  N N 137 
CYS   HG   H  N N 138 
CYS   HXT  H  N N 139 
GLN   N    N  N N 140 
GLN   CA   C  N S 141 
GLN   C    C  N N 142 
GLN   O    O  N N 143 
GLN   CB   C  N N 144 
GLN   CG   C  N N 145 
GLN   CD   C  N N 146 
GLN   OE1  O  N N 147 
GLN   NE2  N  N N 148 
GLN   OXT  O  N N 149 
GLN   H    H  N N 150 
GLN   H2   H  N N 151 
GLN   HA   H  N N 152 
GLN   HB2  H  N N 153 
GLN   HB3  H  N N 154 
GLN   HG2  H  N N 155 
GLN   HG3  H  N N 156 
GLN   HE21 H  N N 157 
GLN   HE22 H  N N 158 
GLN   HXT  H  N N 159 
GLU   N    N  N N 160 
GLU   CA   C  N S 161 
GLU   C    C  N N 162 
GLU   O    O  N N 163 
GLU   CB   C  N N 164 
GLU   CG   C  N N 165 
GLU   CD   C  N N 166 
GLU   OE1  O  N N 167 
GLU   OE2  O  N N 168 
GLU   OXT  O  N N 169 
GLU   H    H  N N 170 
GLU   H2   H  N N 171 
GLU   HA   H  N N 172 
GLU   HB2  H  N N 173 
GLU   HB3  H  N N 174 
GLU   HG2  H  N N 175 
GLU   HG3  H  N N 176 
GLU   HE2  H  N N 177 
GLU   HXT  H  N N 178 
GLY   N    N  N N 179 
GLY   CA   C  N N 180 
GLY   C    C  N N 181 
GLY   O    O  N N 182 
GLY   OXT  O  N N 183 
GLY   H    H  N N 184 
GLY   H2   H  N N 185 
GLY   HA2  H  N N 186 
GLY   HA3  H  N N 187 
GLY   HXT  H  N N 188 
HIS   N    N  N N 189 
HIS   CA   C  N S 190 
HIS   C    C  N N 191 
HIS   O    O  N N 192 
HIS   CB   C  N N 193 
HIS   CG   C  Y N 194 
HIS   ND1  N  Y N 195 
HIS   CD2  C  Y N 196 
HIS   CE1  C  Y N 197 
HIS   NE2  N  Y N 198 
HIS   OXT  O  N N 199 
HIS   H    H  N N 200 
HIS   H2   H  N N 201 
HIS   HA   H  N N 202 
HIS   HB2  H  N N 203 
HIS   HB3  H  N N 204 
HIS   HD1  H  N N 205 
HIS   HD2  H  N N 206 
HIS   HE1  H  N N 207 
HIS   HE2  H  N N 208 
HIS   HXT  H  N N 209 
HOH   O    O  N N 210 
HOH   H1   H  N N 211 
HOH   H2   H  N N 212 
ILE   N    N  N N 213 
ILE   CA   C  N S 214 
ILE   C    C  N N 215 
ILE   O    O  N N 216 
ILE   CB   C  N S 217 
ILE   CG1  C  N N 218 
ILE   CG2  C  N N 219 
ILE   CD1  C  N N 220 
ILE   OXT  O  N N 221 
ILE   H    H  N N 222 
ILE   H2   H  N N 223 
ILE   HA   H  N N 224 
ILE   HB   H  N N 225 
ILE   HG12 H  N N 226 
ILE   HG13 H  N N 227 
ILE   HG21 H  N N 228 
ILE   HG22 H  N N 229 
ILE   HG23 H  N N 230 
ILE   HD11 H  N N 231 
ILE   HD12 H  N N 232 
ILE   HD13 H  N N 233 
ILE   HXT  H  N N 234 
LEU   N    N  N N 235 
LEU   CA   C  N S 236 
LEU   C    C  N N 237 
LEU   O    O  N N 238 
LEU   CB   C  N N 239 
LEU   CG   C  N N 240 
LEU   CD1  C  N N 241 
LEU   CD2  C  N N 242 
LEU   OXT  O  N N 243 
LEU   H    H  N N 244 
LEU   H2   H  N N 245 
LEU   HA   H  N N 246 
LEU   HB2  H  N N 247 
LEU   HB3  H  N N 248 
LEU   HG   H  N N 249 
LEU   HD11 H  N N 250 
LEU   HD12 H  N N 251 
LEU   HD13 H  N N 252 
LEU   HD21 H  N N 253 
LEU   HD22 H  N N 254 
LEU   HD23 H  N N 255 
LEU   HXT  H  N N 256 
LYS   N    N  N N 257 
LYS   CA   C  N S 258 
LYS   C    C  N N 259 
LYS   O    O  N N 260 
LYS   CB   C  N N 261 
LYS   CG   C  N N 262 
LYS   CD   C  N N 263 
LYS   CE   C  N N 264 
LYS   NZ   N  N N 265 
LYS   OXT  O  N N 266 
LYS   H    H  N N 267 
LYS   H2   H  N N 268 
LYS   HA   H  N N 269 
LYS   HB2  H  N N 270 
LYS   HB3  H  N N 271 
LYS   HG2  H  N N 272 
LYS   HG3  H  N N 273 
LYS   HD2  H  N N 274 
LYS   HD3  H  N N 275 
LYS   HE2  H  N N 276 
LYS   HE3  H  N N 277 
LYS   HZ1  H  N N 278 
LYS   HZ2  H  N N 279 
LYS   HZ3  H  N N 280 
LYS   HXT  H  N N 281 
MET   N    N  N N 282 
MET   CA   C  N S 283 
MET   C    C  N N 284 
MET   O    O  N N 285 
MET   CB   C  N N 286 
MET   CG   C  N N 287 
MET   SD   S  N N 288 
MET   CE   C  N N 289 
MET   OXT  O  N N 290 
MET   H    H  N N 291 
MET   H2   H  N N 292 
MET   HA   H  N N 293 
MET   HB2  H  N N 294 
MET   HB3  H  N N 295 
MET   HG2  H  N N 296 
MET   HG3  H  N N 297 
MET   HE1  H  N N 298 
MET   HE2  H  N N 299 
MET   HE3  H  N N 300 
MET   HXT  H  N N 301 
MN    MN   MN N N 302 
PHE   N    N  N N 303 
PHE   CA   C  N S 304 
PHE   C    C  N N 305 
PHE   O    O  N N 306 
PHE   CB   C  N N 307 
PHE   CG   C  Y N 308 
PHE   CD1  C  Y N 309 
PHE   CD2  C  Y N 310 
PHE   CE1  C  Y N 311 
PHE   CE2  C  Y N 312 
PHE   CZ   C  Y N 313 
PHE   OXT  O  N N 314 
PHE   H    H  N N 315 
PHE   H2   H  N N 316 
PHE   HA   H  N N 317 
PHE   HB2  H  N N 318 
PHE   HB3  H  N N 319 
PHE   HD1  H  N N 320 
PHE   HD2  H  N N 321 
PHE   HE1  H  N N 322 
PHE   HE2  H  N N 323 
PHE   HZ   H  N N 324 
PHE   HXT  H  N N 325 
PRO   N    N  N N 326 
PRO   CA   C  N S 327 
PRO   C    C  N N 328 
PRO   O    O  N N 329 
PRO   CB   C  N N 330 
PRO   CG   C  N N 331 
PRO   CD   C  N N 332 
PRO   OXT  O  N N 333 
PRO   H    H  N N 334 
PRO   HA   H  N N 335 
PRO   HB2  H  N N 336 
PRO   HB3  H  N N 337 
PRO   HG2  H  N N 338 
PRO   HG3  H  N N 339 
PRO   HD2  H  N N 340 
PRO   HD3  H  N N 341 
PRO   HXT  H  N N 342 
SER   N    N  N N 343 
SER   CA   C  N S 344 
SER   C    C  N N 345 
SER   O    O  N N 346 
SER   CB   C  N N 347 
SER   OG   O  N N 348 
SER   OXT  O  N N 349 
SER   H    H  N N 350 
SER   H2   H  N N 351 
SER   HA   H  N N 352 
SER   HB2  H  N N 353 
SER   HB3  H  N N 354 
SER   HG   H  N N 355 
SER   HXT  H  N N 356 
THR   N    N  N N 357 
THR   CA   C  N S 358 
THR   C    C  N N 359 
THR   O    O  N N 360 
THR   CB   C  N R 361 
THR   OG1  O  N N 362 
THR   CG2  C  N N 363 
THR   OXT  O  N N 364 
THR   H    H  N N 365 
THR   H2   H  N N 366 
THR   HA   H  N N 367 
THR   HB   H  N N 368 
THR   HG1  H  N N 369 
THR   HG21 H  N N 370 
THR   HG22 H  N N 371 
THR   HG23 H  N N 372 
THR   HXT  H  N N 373 
TRP   N    N  N N 374 
TRP   CA   C  N S 375 
TRP   C    C  N N 376 
TRP   O    O  N N 377 
TRP   CB   C  N N 378 
TRP   CG   C  Y N 379 
TRP   CD1  C  Y N 380 
TRP   CD2  C  Y N 381 
TRP   NE1  N  Y N 382 
TRP   CE2  C  Y N 383 
TRP   CE3  C  Y N 384 
TRP   CZ2  C  Y N 385 
TRP   CZ3  C  Y N 386 
TRP   CH2  C  Y N 387 
TRP   OXT  O  N N 388 
TRP   H    H  N N 389 
TRP   H2   H  N N 390 
TRP   HA   H  N N 391 
TRP   HB2  H  N N 392 
TRP   HB3  H  N N 393 
TRP   HD1  H  N N 394 
TRP   HE1  H  N N 395 
TRP   HE3  H  N N 396 
TRP   HZ2  H  N N 397 
TRP   HZ3  H  N N 398 
TRP   HH2  H  N N 399 
TRP   HXT  H  N N 400 
TYR   N    N  N N 401 
TYR   CA   C  N S 402 
TYR   C    C  N N 403 
TYR   O    O  N N 404 
TYR   CB   C  N N 405 
TYR   CG   C  Y N 406 
TYR   CD1  C  Y N 407 
TYR   CD2  C  Y N 408 
TYR   CE1  C  Y N 409 
TYR   CE2  C  Y N 410 
TYR   CZ   C  Y N 411 
TYR   OH   O  N N 412 
TYR   OXT  O  N N 413 
TYR   H    H  N N 414 
TYR   H2   H  N N 415 
TYR   HA   H  N N 416 
TYR   HB2  H  N N 417 
TYR   HB3  H  N N 418 
TYR   HD1  H  N N 419 
TYR   HD2  H  N N 420 
TYR   HE1  H  N N 421 
TYR   HE2  H  N N 422 
TYR   HH   H  N N 423 
TYR   HXT  H  N N 424 
VAL   N    N  N N 425 
VAL   CA   C  N S 426 
VAL   C    C  N N 427 
VAL   O    O  N N 428 
VAL   CB   C  N N 429 
VAL   CG1  C  N N 430 
VAL   CG2  C  N N 431 
VAL   OXT  O  N N 432 
VAL   H    H  N N 433 
VAL   H2   H  N N 434 
VAL   HA   H  N N 435 
VAL   HB   H  N N 436 
VAL   HG11 H  N N 437 
VAL   HG12 H  N N 438 
VAL   HG13 H  N N 439 
VAL   HG21 H  N N 440 
VAL   HG22 H  N N 441 
VAL   HG23 H  N N 442 
VAL   HXT  H  N N 443 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1AVY C02 C01  doub Y N 1   
A1AVY C04 N03  doub Y N 2   
A1AVY C06 C05  doub Y N 3   
A1AVY C05 C04  sing Y N 4   
A1AVY C07 C04  sing N N 5   
A1AVY F08 C07  sing N N 6   
A1AVY F09 C07  sing N N 7   
A1AVY F10 C07  sing N N 8   
A1AVY N03 C02  sing Y N 9   
A1AVY N11 C02  sing N N 10  
A1AVY C12 N11  sing N N 11  
A1AVY C13 C12  sing N N 12  
A1AVY N14 C13  sing N N 13  
A1AVY C16 C15  sing N N 14  
A1AVY C15 N14  sing N N 15  
A1AVY S17 N14  sing N N 16  
A1AVY O18 S17  doub N N 17  
A1AVY O19 S17  doub N N 18  
A1AVY C20 S17  sing N N 19  
A1AVY C21 C20  doub Y N 20  
A1AVY C22 C21  sing Y N 21  
A1AVY C23 C22  doub Y N 22  
A1AVY C24 C23  sing Y N 23  
A1AVY C25 C24  doub Y N 24  
A1AVY C26 C24  sing N N 25  
A1AVY C27 C26  sing N N 26  
A1AVY N28 C27  sing N N 27  
A1AVY C29 N28  sing N N 28  
A1AVY O30 C29  doub N N 29  
A1AVY C31 C29  sing N N 30  
A1AVY C01 C06  sing Y N 31  
A1AVY N11 C16  sing N N 32  
A1AVY C20 C25  sing Y N 33  
A1AVY C23 N28  sing N N 34  
A1AVY C13 H131 sing N N 35  
A1AVY C13 H132 sing N N 36  
A1AVY C15 H152 sing N N 37  
A1AVY C15 H151 sing N N 38  
A1AVY C21 H211 sing N N 39  
A1AVY C22 H221 sing N N 40  
A1AVY C26 H262 sing N N 41  
A1AVY C26 H261 sing N N 42  
A1AVY C01 H011 sing N N 43  
A1AVY C05 H051 sing N N 44  
A1AVY C06 H061 sing N N 45  
A1AVY C12 H121 sing N N 46  
A1AVY C12 H122 sing N N 47  
A1AVY C16 H161 sing N N 48  
A1AVY C16 H162 sing N N 49  
A1AVY C25 H251 sing N N 50  
A1AVY C27 H272 sing N N 51  
A1AVY C27 H271 sing N N 52  
A1AVY C31 H312 sing N N 53  
A1AVY C31 H311 sing N N 54  
A1AVY C31 H313 sing N N 55  
ALA   N   CA   sing N N 56  
ALA   N   H    sing N N 57  
ALA   N   H2   sing N N 58  
ALA   CA  C    sing N N 59  
ALA   CA  CB   sing N N 60  
ALA   CA  HA   sing N N 61  
ALA   C   O    doub N N 62  
ALA   C   OXT  sing N N 63  
ALA   CB  HB1  sing N N 64  
ALA   CB  HB2  sing N N 65  
ALA   CB  HB3  sing N N 66  
ALA   OXT HXT  sing N N 67  
ARG   N   CA   sing N N 68  
ARG   N   H    sing N N 69  
ARG   N   H2   sing N N 70  
ARG   CA  C    sing N N 71  
ARG   CA  CB   sing N N 72  
ARG   CA  HA   sing N N 73  
ARG   C   O    doub N N 74  
ARG   C   OXT  sing N N 75  
ARG   CB  CG   sing N N 76  
ARG   CB  HB2  sing N N 77  
ARG   CB  HB3  sing N N 78  
ARG   CG  CD   sing N N 79  
ARG   CG  HG2  sing N N 80  
ARG   CG  HG3  sing N N 81  
ARG   CD  NE   sing N N 82  
ARG   CD  HD2  sing N N 83  
ARG   CD  HD3  sing N N 84  
ARG   NE  CZ   sing N N 85  
ARG   NE  HE   sing N N 86  
ARG   CZ  NH1  sing N N 87  
ARG   CZ  NH2  doub N N 88  
ARG   NH1 HH11 sing N N 89  
ARG   NH1 HH12 sing N N 90  
ARG   NH2 HH21 sing N N 91  
ARG   NH2 HH22 sing N N 92  
ARG   OXT HXT  sing N N 93  
ASN   N   CA   sing N N 94  
ASN   N   H    sing N N 95  
ASN   N   H2   sing N N 96  
ASN   CA  C    sing N N 97  
ASN   CA  CB   sing N N 98  
ASN   CA  HA   sing N N 99  
ASN   C   O    doub N N 100 
ASN   C   OXT  sing N N 101 
ASN   CB  CG   sing N N 102 
ASN   CB  HB2  sing N N 103 
ASN   CB  HB3  sing N N 104 
ASN   CG  OD1  doub N N 105 
ASN   CG  ND2  sing N N 106 
ASN   ND2 HD21 sing N N 107 
ASN   ND2 HD22 sing N N 108 
ASN   OXT HXT  sing N N 109 
ASP   N   CA   sing N N 110 
ASP   N   H    sing N N 111 
ASP   N   H2   sing N N 112 
ASP   CA  C    sing N N 113 
ASP   CA  CB   sing N N 114 
ASP   CA  HA   sing N N 115 
ASP   C   O    doub N N 116 
ASP   C   OXT  sing N N 117 
ASP   CB  CG   sing N N 118 
ASP   CB  HB2  sing N N 119 
ASP   CB  HB3  sing N N 120 
ASP   CG  OD1  doub N N 121 
ASP   CG  OD2  sing N N 122 
ASP   OD2 HD2  sing N N 123 
ASP   OXT HXT  sing N N 124 
CYS   N   CA   sing N N 125 
CYS   N   H    sing N N 126 
CYS   N   H2   sing N N 127 
CYS   CA  C    sing N N 128 
CYS   CA  CB   sing N N 129 
CYS   CA  HA   sing N N 130 
CYS   C   O    doub N N 131 
CYS   C   OXT  sing N N 132 
CYS   CB  SG   sing N N 133 
CYS   CB  HB2  sing N N 134 
CYS   CB  HB3  sing N N 135 
CYS   SG  HG   sing N N 136 
CYS   OXT HXT  sing N N 137 
GLN   N   CA   sing N N 138 
GLN   N   H    sing N N 139 
GLN   N   H2   sing N N 140 
GLN   CA  C    sing N N 141 
GLN   CA  CB   sing N N 142 
GLN   CA  HA   sing N N 143 
GLN   C   O    doub N N 144 
GLN   C   OXT  sing N N 145 
GLN   CB  CG   sing N N 146 
GLN   CB  HB2  sing N N 147 
GLN   CB  HB3  sing N N 148 
GLN   CG  CD   sing N N 149 
GLN   CG  HG2  sing N N 150 
GLN   CG  HG3  sing N N 151 
GLN   CD  OE1  doub N N 152 
GLN   CD  NE2  sing N N 153 
GLN   NE2 HE21 sing N N 154 
GLN   NE2 HE22 sing N N 155 
GLN   OXT HXT  sing N N 156 
GLU   N   CA   sing N N 157 
GLU   N   H    sing N N 158 
GLU   N   H2   sing N N 159 
GLU   CA  C    sing N N 160 
GLU   CA  CB   sing N N 161 
GLU   CA  HA   sing N N 162 
GLU   C   O    doub N N 163 
GLU   C   OXT  sing N N 164 
GLU   CB  CG   sing N N 165 
GLU   CB  HB2  sing N N 166 
GLU   CB  HB3  sing N N 167 
GLU   CG  CD   sing N N 168 
GLU   CG  HG2  sing N N 169 
GLU   CG  HG3  sing N N 170 
GLU   CD  OE1  doub N N 171 
GLU   CD  OE2  sing N N 172 
GLU   OE2 HE2  sing N N 173 
GLU   OXT HXT  sing N N 174 
GLY   N   CA   sing N N 175 
GLY   N   H    sing N N 176 
GLY   N   H2   sing N N 177 
GLY   CA  C    sing N N 178 
GLY   CA  HA2  sing N N 179 
GLY   CA  HA3  sing N N 180 
GLY   C   O    doub N N 181 
GLY   C   OXT  sing N N 182 
GLY   OXT HXT  sing N N 183 
HIS   N   CA   sing N N 184 
HIS   N   H    sing N N 185 
HIS   N   H2   sing N N 186 
HIS   CA  C    sing N N 187 
HIS   CA  CB   sing N N 188 
HIS   CA  HA   sing N N 189 
HIS   C   O    doub N N 190 
HIS   C   OXT  sing N N 191 
HIS   CB  CG   sing N N 192 
HIS   CB  HB2  sing N N 193 
HIS   CB  HB3  sing N N 194 
HIS   CG  ND1  sing Y N 195 
HIS   CG  CD2  doub Y N 196 
HIS   ND1 CE1  doub Y N 197 
HIS   ND1 HD1  sing N N 198 
HIS   CD2 NE2  sing Y N 199 
HIS   CD2 HD2  sing N N 200 
HIS   CE1 NE2  sing Y N 201 
HIS   CE1 HE1  sing N N 202 
HIS   NE2 HE2  sing N N 203 
HIS   OXT HXT  sing N N 204 
HOH   O   H1   sing N N 205 
HOH   O   H2   sing N N 206 
ILE   N   CA   sing N N 207 
ILE   N   H    sing N N 208 
ILE   N   H2   sing N N 209 
ILE   CA  C    sing N N 210 
ILE   CA  CB   sing N N 211 
ILE   CA  HA   sing N N 212 
ILE   C   O    doub N N 213 
ILE   C   OXT  sing N N 214 
ILE   CB  CG1  sing N N 215 
ILE   CB  CG2  sing N N 216 
ILE   CB  HB   sing N N 217 
ILE   CG1 CD1  sing N N 218 
ILE   CG1 HG12 sing N N 219 
ILE   CG1 HG13 sing N N 220 
ILE   CG2 HG21 sing N N 221 
ILE   CG2 HG22 sing N N 222 
ILE   CG2 HG23 sing N N 223 
ILE   CD1 HD11 sing N N 224 
ILE   CD1 HD12 sing N N 225 
ILE   CD1 HD13 sing N N 226 
ILE   OXT HXT  sing N N 227 
LEU   N   CA   sing N N 228 
LEU   N   H    sing N N 229 
LEU   N   H2   sing N N 230 
LEU   CA  C    sing N N 231 
LEU   CA  CB   sing N N 232 
LEU   CA  HA   sing N N 233 
LEU   C   O    doub N N 234 
LEU   C   OXT  sing N N 235 
LEU   CB  CG   sing N N 236 
LEU   CB  HB2  sing N N 237 
LEU   CB  HB3  sing N N 238 
LEU   CG  CD1  sing N N 239 
LEU   CG  CD2  sing N N 240 
LEU   CG  HG   sing N N 241 
LEU   CD1 HD11 sing N N 242 
LEU   CD1 HD12 sing N N 243 
LEU   CD1 HD13 sing N N 244 
LEU   CD2 HD21 sing N N 245 
LEU   CD2 HD22 sing N N 246 
LEU   CD2 HD23 sing N N 247 
LEU   OXT HXT  sing N N 248 
LYS   N   CA   sing N N 249 
LYS   N   H    sing N N 250 
LYS   N   H2   sing N N 251 
LYS   CA  C    sing N N 252 
LYS   CA  CB   sing N N 253 
LYS   CA  HA   sing N N 254 
LYS   C   O    doub N N 255 
LYS   C   OXT  sing N N 256 
LYS   CB  CG   sing N N 257 
LYS   CB  HB2  sing N N 258 
LYS   CB  HB3  sing N N 259 
LYS   CG  CD   sing N N 260 
LYS   CG  HG2  sing N N 261 
LYS   CG  HG3  sing N N 262 
LYS   CD  CE   sing N N 263 
LYS   CD  HD2  sing N N 264 
LYS   CD  HD3  sing N N 265 
LYS   CE  NZ   sing N N 266 
LYS   CE  HE2  sing N N 267 
LYS   CE  HE3  sing N N 268 
LYS   NZ  HZ1  sing N N 269 
LYS   NZ  HZ2  sing N N 270 
LYS   NZ  HZ3  sing N N 271 
LYS   OXT HXT  sing N N 272 
MET   N   CA   sing N N 273 
MET   N   H    sing N N 274 
MET   N   H2   sing N N 275 
MET   CA  C    sing N N 276 
MET   CA  CB   sing N N 277 
MET   CA  HA   sing N N 278 
MET   C   O    doub N N 279 
MET   C   OXT  sing N N 280 
MET   CB  CG   sing N N 281 
MET   CB  HB2  sing N N 282 
MET   CB  HB3  sing N N 283 
MET   CG  SD   sing N N 284 
MET   CG  HG2  sing N N 285 
MET   CG  HG3  sing N N 286 
MET   SD  CE   sing N N 287 
MET   CE  HE1  sing N N 288 
MET   CE  HE2  sing N N 289 
MET   CE  HE3  sing N N 290 
MET   OXT HXT  sing N N 291 
PHE   N   CA   sing N N 292 
PHE   N   H    sing N N 293 
PHE   N   H2   sing N N 294 
PHE   CA  C    sing N N 295 
PHE   CA  CB   sing N N 296 
PHE   CA  HA   sing N N 297 
PHE   C   O    doub N N 298 
PHE   C   OXT  sing N N 299 
PHE   CB  CG   sing N N 300 
PHE   CB  HB2  sing N N 301 
PHE   CB  HB3  sing N N 302 
PHE   CG  CD1  doub Y N 303 
PHE   CG  CD2  sing Y N 304 
PHE   CD1 CE1  sing Y N 305 
PHE   CD1 HD1  sing N N 306 
PHE   CD2 CE2  doub Y N 307 
PHE   CD2 HD2  sing N N 308 
PHE   CE1 CZ   doub Y N 309 
PHE   CE1 HE1  sing N N 310 
PHE   CE2 CZ   sing Y N 311 
PHE   CE2 HE2  sing N N 312 
PHE   CZ  HZ   sing N N 313 
PHE   OXT HXT  sing N N 314 
PRO   N   CA   sing N N 315 
PRO   N   CD   sing N N 316 
PRO   N   H    sing N N 317 
PRO   CA  C    sing N N 318 
PRO   CA  CB   sing N N 319 
PRO   CA  HA   sing N N 320 
PRO   C   O    doub N N 321 
PRO   C   OXT  sing N N 322 
PRO   CB  CG   sing N N 323 
PRO   CB  HB2  sing N N 324 
PRO   CB  HB3  sing N N 325 
PRO   CG  CD   sing N N 326 
PRO   CG  HG2  sing N N 327 
PRO   CG  HG3  sing N N 328 
PRO   CD  HD2  sing N N 329 
PRO   CD  HD3  sing N N 330 
PRO   OXT HXT  sing N N 331 
SER   N   CA   sing N N 332 
SER   N   H    sing N N 333 
SER   N   H2   sing N N 334 
SER   CA  C    sing N N 335 
SER   CA  CB   sing N N 336 
SER   CA  HA   sing N N 337 
SER   C   O    doub N N 338 
SER   C   OXT  sing N N 339 
SER   CB  OG   sing N N 340 
SER   CB  HB2  sing N N 341 
SER   CB  HB3  sing N N 342 
SER   OG  HG   sing N N 343 
SER   OXT HXT  sing N N 344 
THR   N   CA   sing N N 345 
THR   N   H    sing N N 346 
THR   N   H2   sing N N 347 
THR   CA  C    sing N N 348 
THR   CA  CB   sing N N 349 
THR   CA  HA   sing N N 350 
THR   C   O    doub N N 351 
THR   C   OXT  sing N N 352 
THR   CB  OG1  sing N N 353 
THR   CB  CG2  sing N N 354 
THR   CB  HB   sing N N 355 
THR   OG1 HG1  sing N N 356 
THR   CG2 HG21 sing N N 357 
THR   CG2 HG22 sing N N 358 
THR   CG2 HG23 sing N N 359 
THR   OXT HXT  sing N N 360 
TRP   N   CA   sing N N 361 
TRP   N   H    sing N N 362 
TRP   N   H2   sing N N 363 
TRP   CA  C    sing N N 364 
TRP   CA  CB   sing N N 365 
TRP   CA  HA   sing N N 366 
TRP   C   O    doub N N 367 
TRP   C   OXT  sing N N 368 
TRP   CB  CG   sing N N 369 
TRP   CB  HB2  sing N N 370 
TRP   CB  HB3  sing N N 371 
TRP   CG  CD1  doub Y N 372 
TRP   CG  CD2  sing Y N 373 
TRP   CD1 NE1  sing Y N 374 
TRP   CD1 HD1  sing N N 375 
TRP   CD2 CE2  doub Y N 376 
TRP   CD2 CE3  sing Y N 377 
TRP   NE1 CE2  sing Y N 378 
TRP   NE1 HE1  sing N N 379 
TRP   CE2 CZ2  sing Y N 380 
TRP   CE3 CZ3  doub Y N 381 
TRP   CE3 HE3  sing N N 382 
TRP   CZ2 CH2  doub Y N 383 
TRP   CZ2 HZ2  sing N N 384 
TRP   CZ3 CH2  sing Y N 385 
TRP   CZ3 HZ3  sing N N 386 
TRP   CH2 HH2  sing N N 387 
TRP   OXT HXT  sing N N 388 
TYR   N   CA   sing N N 389 
TYR   N   H    sing N N 390 
TYR   N   H2   sing N N 391 
TYR   CA  C    sing N N 392 
TYR   CA  CB   sing N N 393 
TYR   CA  HA   sing N N 394 
TYR   C   O    doub N N 395 
TYR   C   OXT  sing N N 396 
TYR   CB  CG   sing N N 397 
TYR   CB  HB2  sing N N 398 
TYR   CB  HB3  sing N N 399 
TYR   CG  CD1  doub Y N 400 
TYR   CG  CD2  sing Y N 401 
TYR   CD1 CE1  sing Y N 402 
TYR   CD1 HD1  sing N N 403 
TYR   CD2 CE2  doub Y N 404 
TYR   CD2 HD2  sing N N 405 
TYR   CE1 CZ   doub Y N 406 
TYR   CE1 HE1  sing N N 407 
TYR   CE2 CZ   sing Y N 408 
TYR   CE2 HE2  sing N N 409 
TYR   CZ  OH   sing N N 410 
TYR   OH  HH   sing N N 411 
TYR   OXT HXT  sing N N 412 
VAL   N   CA   sing N N 413 
VAL   N   H    sing N N 414 
VAL   N   H2   sing N N 415 
VAL   CA  C    sing N N 416 
VAL   CA  CB   sing N N 417 
VAL   CA  HA   sing N N 418 
VAL   C   O    doub N N 419 
VAL   C   OXT  sing N N 420 
VAL   CB  CG1  sing N N 421 
VAL   CB  CG2  sing N N 422 
VAL   CB  HB   sing N N 423 
VAL   CG1 HG11 sing N N 424 
VAL   CG1 HG12 sing N N 425 
VAL   CG1 HG13 sing N N 426 
VAL   CG2 HG21 sing N N 427 
VAL   CG2 HG22 sing N N 428 
VAL   CG2 HG23 sing N N 429 
VAL   OXT HXT  sing N N 430 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6PJ3 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 32 2 1' 
_space_group.name_Hall        
;P 32 2"
;
_space_group.IT_number        154 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9CCY 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009460 
_atom_sites.fract_transf_matrix[1][2]   0.005462 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.010923 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.018671 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
F  ? ? 4.90428  4.07044 ? ? 12.99538 1.63651  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
MN ? ? 20.23591 4.67902 ? ? 2.76514  44.01191 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ALA   A 1 2   ? -31.12582 -43.10425 7.84368   1.000 36.82016 ? 2   ALA   A N   1 
ATOM   2    C  CA  . ALA   A 1 2   ? -30.42927 -41.85762 7.53425   1.000 40.15083 ? 2   ALA   A CA  1 
ATOM   3    C  C   . ALA   A 1 2   ? -31.28330 -40.63811 7.86932   1.000 35.73157 ? 2   ALA   A C   1 
ATOM   4    O  O   . ALA   A 1 2   ? -32.51015 -40.68508 7.78636   1.000 36.40913 ? 2   ALA   A O   1 
ATOM   5    C  CB  . ALA   A 1 2   ? -30.03186 -41.82921 6.07064   1.000 38.52978 ? 2   ALA   A CB  1 
ATOM   6    N  N   . THR   A 1 3   ? -30.62440 -39.55114 8.25628   1.000 33.33056 ? 3   THR   A N   1 
ATOM   7    C  CA  . THR   A 1 3   ? -31.26417 -38.26213 8.48375   1.000 34.76088 ? 3   THR   A CA  1 
ATOM   8    C  C   . THR   A 1 3   ? -30.78349 -37.29236 7.41262   1.000 35.64151 ? 3   THR   A C   1 
ATOM   9    O  O   . THR   A 1 3   ? -29.57995 -37.21395 7.14186   1.000 32.64171 ? 3   THR   A O   1 
ATOM   10   C  CB  . THR   A 1 3   ? -30.93248 -37.73568 9.88291   1.000 37.50634 ? 3   THR   A CB  1 
ATOM   11   O  OG1 . THR   A 1 3   ? -31.37904 -38.68593 10.86165  1.000 35.25228 ? 3   THR   A OG1 1 
ATOM   12   C  CG2 . THR   A 1 3   ? -31.59420 -36.39188 10.13612  1.000 29.38487 ? 3   THR   A CG2 1 
ATOM   13   N  N   . LEU   A 1 4   ? -31.71829 -36.57347 6.79190   1.000 30.38390 ? 4   LEU   A N   1 
ATOM   14   C  CA  . LEU   A 1 4   ? -31.41816 -35.73697 5.63584   1.000 32.96833 ? 4   LEU   A CA  1 
ATOM   15   C  C   . LEU   A 1 4   ? -31.43233 -34.26653 6.02595   1.000 33.56466 ? 4   LEU   A C   1 
ATOM   16   O  O   . LEU   A 1 4   ? -32.23756 -33.84567 6.86394   1.000 32.39922 ? 4   LEU   A O   1 
ATOM   17   C  CB  . LEU   A 1 4   ? -32.41949 -35.98007 4.49811   1.000 31.13073 ? 4   LEU   A CB  1 
ATOM   18   C  CG  . LEU   A 1 4   ? -32.51765 -37.42958 4.01514   1.000 36.32642 ? 4   LEU   A CG  1 
ATOM   19   C  CD1 . LEU   A 1 4   ? -33.45319 -37.53246 2.82223   1.000 37.01783 ? 4   LEU   A CD1 1 
ATOM   20   C  CD2 . LEU   A 1 4   ? -31.13848 -37.98562 3.68002   1.000 34.04838 ? 4   LEU   A CD2 1 
ATOM   21   N  N   . PHE   A 1 5   ? -30.52414 -33.49591 5.42008   1.000 32.66300 ? 5   PHE   A N   1 
ATOM   22   C  CA  . PHE   A 1 5   ? -30.43553 -32.05304 5.61965   1.000 29.85894 ? 5   PHE   A CA  1 
ATOM   23   C  C   . PHE   A 1 5   ? -30.37711 -31.35985 4.26837   1.000 32.68693 ? 5   PHE   A C   1 
ATOM   24   O  O   . PHE   A 1 5   ? -29.58099 -31.74303 3.40774   1.000 29.33870 ? 5   PHE   A O   1 
ATOM   25   C  CB  . PHE   A 1 5   ? -29.19909 -31.67560 6.44417   1.000 31.51020 ? 5   PHE   A CB  1 
ATOM   26   C  CG  . PHE   A 1 5   ? -29.20094 -32.26156 7.82730   1.000 34.91752 ? 5   PHE   A CG  1 
ATOM   27   C  CD1 . PHE   A 1 5   ? -28.73394 -33.54975 8.05202   1.000 32.04974 ? 5   PHE   A CD1 1 
ATOM   28   C  CD2 . PHE   A 1 5   ? -29.70011 -31.53541 8.89636   1.000 32.93129 ? 5   PHE   A CD2 1 
ATOM   29   C  CE1 . PHE   A 1 5   ? -28.75672 -34.09776 9.32728   1.000 34.49762 ? 5   PHE   A CE1 1 
ATOM   30   C  CE2 . PHE   A 1 5   ? -29.72526 -32.07790 10.17265  1.000 31.93293 ? 5   PHE   A CE2 1 
ATOM   31   C  CZ  . PHE   A 1 5   ? -29.25851 -33.35255 10.38734  1.000 31.10944 ? 5   PHE   A CZ  1 
ATOM   32   N  N   . ILE   A 1 6   ? -31.19845 -30.32311 4.09316   1.000 29.40054 ? 6   ILE   A N   1 
ATOM   33   C  CA  . ILE   A 1 6   ? -31.17995 -29.50246 2.88815   1.000 31.38738 ? 6   ILE   A CA  1 
ATOM   34   C  C   . ILE   A 1 6   ? -31.32674 -28.04695 3.31004   1.000 30.45425 ? 6   ILE   A C   1 
ATOM   35   O  O   . ILE   A 1 6   ? -31.77016 -27.74332 4.41812   1.000 30.62426 ? 6   ILE   A O   1 
ATOM   36   C  CB  . ILE   A 1 6   ? -32.30184 -29.88178 1.89560   1.000 28.10592 ? 6   ILE   A CB  1 
ATOM   37   C  CG1 . ILE   A 1 6   ? -33.66535 -29.66871 2.55827   1.000 31.44084 ? 6   ILE   A CG1 1 
ATOM   38   C  CG2 . ILE   A 1 6   ? -32.13820 -31.32327 1.39306   1.000 29.71339 ? 6   ILE   A CG2 1 
ATOM   39   C  CD1 . ILE   A 1 6   ? -34.85704 -29.97893 1.65915   1.000 28.83283 ? 6   ILE   A CD1 1 
ATOM   40   N  N   . ALA   A 1 7   ? -30.95053 -27.14354 2.40854   1.000 28.62722 ? 7   ALA   A N   1 
ATOM   41   C  CA  . ALA   A 1 7   ? -31.07821 -25.70926 2.65314   1.000 31.60895 ? 7   ALA   A CA  1 
ATOM   42   C  C   . ALA   A 1 7   ? -30.89192 -24.97361 1.33467   1.000 35.64369 ? 7   ALA   A C   1 
ATOM   43   O  O   . ALA   A 1 7   ? -30.43755 -25.54503 0.33759   1.000 32.81817 ? 7   ALA   A O   1 
ATOM   44   C  CB  . ALA   A 1 7   ? -30.06323 -25.21265 3.68941   1.000 30.31263 ? 7   ALA   A CB  1 
ATOM   45   N  N   . ASP   A 1 8   ? -31.24711 -23.68676 1.34818   1.000 31.27640 ? 8   ASP   A N   1 
ATOM   46   C  CA  . ASP   A 1 8   ? -30.92599 -22.77092 0.25841   1.000 32.84036 ? 8   ASP   A CA  1 
ATOM   47   C  C   . ASP   A 1 8   ? -31.49017 -23.25976 -1.07551  1.000 33.50974 ? 8   ASP   A C   1 
ATOM   48   O  O   . ASP   A 1 8   ? -30.81186 -23.27088 -2.10679  1.000 32.16009 ? 8   ASP   A O   1 
ATOM   49   C  CB  . ASP   A 1 8   ? -29.41283 -22.54291 0.19403   1.000 35.29600 ? 8   ASP   A CB  1 
ATOM   50   C  CG  . ASP   A 1 8   ? -28.86803 -22.00761 1.50276   1.000 37.18713 ? 8   ASP   A CG  1 
ATOM   51   O  OD1 . ASP   A 1 8   ? -29.34338 -20.93622 1.92793   1.000 37.47206 ? 8   ASP   A OD1 1 
ATOM   52   O  OD2 . ASP   A 1 8   ? -27.99664 -22.65440 2.12114   1.000 40.90059 ? 8   ASP   A OD2 1 
ATOM   53   N  N   . LEU   A 1 9   ? -32.75998 -23.67013 -1.03896  1.000 33.03904 ? 9   LEU   A N   1 
ATOM   54   C  CA  . LEU   A 1 9   ? -33.49936 -23.98171 -2.25365  1.000 33.47664 ? 9   LEU   A CA  1 
ATOM   55   C  C   . LEU   A 1 9   ? -33.97343 -22.71723 -2.96331  1.000 31.96282 ? 9   LEU   A C   1 
ATOM   56   O  O   . LEU   A 1 9   ? -34.04746 -22.69642 -4.19557  1.000 30.47705 ? 9   LEU   A O   1 
ATOM   57   C  CB  . LEU   A 1 9   ? -34.69515 -24.88118 -1.91834  1.000 30.50780 ? 9   LEU   A CB  1 
ATOM   58   C  CG  . LEU   A 1 9   ? -34.35600 -26.33174 -1.54407  1.000 33.73440 ? 9   LEU   A CG  1 
ATOM   59   C  CD1 . LEU   A 1 9   ? -34.07235 -26.46286 -0.04661  1.000 31.57375 ? 9   LEU   A CD1 1 
ATOM   60   C  CD2 . LEU   A 1 9   ? -35.46992 -27.27672 -1.96434  1.000 31.07329 ? 9   LEU   A CD2 1 
ATOM   61   N  N   . HIS   A 1 10  ? -34.29501 -21.66567 -2.20793  1.000 30.94031 ? 10  HIS   A N   1 
ATOM   62   C  CA  . HIS   A 1 10  ? -34.77702 -20.39501 -2.76382  1.000 32.30984 ? 10  HIS   A CA  1 
ATOM   63   C  C   . HIS   A 1 10  ? -35.93565 -20.60711 -3.73565  1.000 30.85274 ? 10  HIS   A C   1 
ATOM   64   O  O   . HIS   A 1 10  ? -35.95337 -20.08110 -4.84984  1.000 32.93106 ? 10  HIS   A O   1 
ATOM   65   C  CB  . HIS   A 1 10  ? -33.63955 -19.62565 -3.43587  1.000 36.88723 ? 10  HIS   A CB  1 
ATOM   66   C  CG  . HIS   A 1 10  ? -32.45821 -19.39791 -2.54320  1.000 36.89039 ? 10  HIS   A CG  1 
ATOM   67   N  ND1 . HIS   A 1 10  ? -32.27918 -18.23265 -1.82971  1.000 43.30225 ? 10  HIS   A ND1 1 
ATOM   68   C  CD2 . HIS   A 1 10  ? -31.39857 -20.18585 -2.24719  1.000 41.10412 ? 10  HIS   A CD2 1 
ATOM   69   C  CE1 . HIS   A 1 10  ? -31.16420 -18.31540 -1.12591  1.000 40.12355 ? 10  HIS   A CE1 1 
ATOM   70   N  NE2 . HIS   A 1 10  ? -30.60923 -19.48977 -1.36363  1.000 43.45569 ? 10  HIS   A NE2 1 
ATOM   71   N  N   . LEU   A 1 11  ? -36.91351 -21.39599 -3.30575  1.000 31.00548 ? 11  LEU   A N   1 
ATOM   72   C  CA  . LEU   A 1 11  ? -38.06771 -21.67165 -4.15479  1.000 32.36757 ? 11  LEU   A CA  1 
ATOM   73   C  C   . LEU   A 1 11  ? -38.78886 -20.37762 -4.53180  1.000 35.66410 ? 11  LEU   A C   1 
ATOM   74   O  O   . LEU   A 1 11  ? -38.94476 -19.47015 -3.71069  1.000 32.00311 ? 11  LEU   A O   1 
ATOM   75   C  CB  . LEU   A 1 11  ? -39.02204 -22.63020 -3.44494  1.000 29.87444 ? 11  LEU   A CB  1 
ATOM   76   C  CG  . LEU   A 1 11  ? -38.43161 -24.02002 -3.14785  1.000 33.25613 ? 11  LEU   A CG  1 
ATOM   77   C  CD1 . LEU   A 1 11  ? -39.40474 -24.85288 -2.33350  1.000 30.82947 ? 11  LEU   A CD1 1 
ATOM   78   C  CD2 . LEU   A 1 11  ? -38.04388 -24.74401 -4.43337  1.000 32.28012 ? 11  LEU   A CD2 1 
ATOM   79   N  N   . GLN   A 1 12  ? -39.21447 -20.29658 -5.79203  1.000 32.93763 ? 12  GLN   A N   1 
ATOM   80   C  CA  . GLN   A 1 12  ? -39.86770 -19.11777 -6.34593  1.000 36.96355 ? 12  GLN   A CA  1 
ATOM   81   C  C   . GLN   A 1 12  ? -40.58353 -19.54430 -7.61606  1.000 37.17742 ? 12  GLN   A C   1 
ATOM   82   O  O   . GLN   A 1 12  ? -40.09689 -20.41166 -8.34613  1.000 33.64993 ? 12  GLN   A O   1 
ATOM   83   C  CB  . GLN   A 1 12  ? -38.85453 -18.00310 -6.64268  1.000 39.75858 ? 12  GLN   A CB  1 
ATOM   84   C  CG  . GLN   A 1 12  ? -37.63944 -18.49265 -7.43259  1.000 36.89745 ? 12  GLN   A CG  1 
ATOM   85   C  CD  . GLN   A 1 12  ? -36.50961 -17.47781 -7.50189  1.000 45.20168 ? 12  GLN   A CD  1 
ATOM   86   O  OE1 . GLN   A 1 12  ? -35.40729 -17.73266 -7.01313  1.000 48.69758 ? 12  GLN   A OE1 1 
ATOM   87   N  NE2 . GLN   A 1 12  ? -36.76549 -16.34467 -8.13053  1.000 42.11188 ? 12  GLN   A NE2 1 
ATOM   88   N  N   . THR   A 1 13  ? -41.74401 -18.92928 -7.87513  1.000 34.38627 ? 13  THR   A N   1 
ATOM   89   C  CA  . THR   A 1 13  ? -42.54454 -19.33662 -9.02334  1.000 36.94847 ? 13  THR   A CA  1 
ATOM   90   C  C   . THR   A 1 13  ? -41.81971 -19.08656 -10.33868 1.000 38.48058 ? 13  THR   A C   1 
ATOM   91   O  O   . THR   A 1 13  ? -42.15823 -19.71076 -11.35112 1.000 38.51793 ? 13  THR   A O   1 
ATOM   92   C  CB  . THR   A 1 13  ? -43.90226 -18.61425 -9.01741  1.000 45.40616 ? 13  THR   A CB  1 
ATOM   93   O  OG1 . THR   A 1 13  ? -43.70546 -17.20489 -8.86939  1.000 43.56328 ? 13  THR   A OG1 1 
ATOM   94   C  CG2 . THR   A 1 13  ? -44.76042 -19.10547 -7.84931  1.000 39.98912 ? 13  THR   A CG2 1 
ATOM   95   N  N   . GLU   A 1 14  ? -40.82206 -18.20234 -10.34408 1.000 37.99996 ? 14  GLU   A N   1 
ATOM   96   C  CA  . GLU   A 1 14  ? -40.02093 -17.96216 -11.53621 1.000 41.66662 ? 14  GLU   A CA  1 
ATOM   97   C  C   . GLU   A 1 14  ? -39.02583 -19.07831 -11.82936 1.000 40.24730 ? 14  GLU   A C   1 
ATOM   98   O  O   . GLU   A 1 14  ? -38.43437 -19.08205 -12.91312 1.000 41.24553 ? 14  GLU   A O   1 
ATOM   99   C  CB  . GLU   A 1 14  ? -39.26777 -16.63474 -11.40632 1.000 40.43137 ? 14  GLU   A CB  1 
ATOM   100  C  CG  . GLU   A 1 14  ? -40.16493 -15.40398 -11.44220 1.000 44.98794 ? 14  GLU   A CG  1 
ATOM   101  C  CD  . GLU   A 1 14  ? -40.72517 -15.04356 -10.07817 1.000 56.89252 ? 14  GLU   A CD  1 
ATOM   102  O  OE1 . GLU   A 1 14  ? -40.41360 -15.75399 -9.09322  1.000 45.39422 ? 14  GLU   A OE1 1 
ATOM   103  O  OE2 . GLU   A 1 14  ? -41.47606 -14.04687 -9.99271  1.000 67.26596 ? 14  GLU   A OE2 1 
ATOM   104  N  N   . GLU   A 1 15  ? -38.82385 -20.01854 -10.90798 1.000 36.04273 ? 15  GLU   A N   1 
ATOM   105  C  CA  . GLU   A 1 15  ? -37.87022 -21.11514 -11.08877 1.000 39.06241 ? 15  GLU   A CA  1 
ATOM   106  C  C   . GLU   A 1 15  ? -38.58376 -22.44755 -10.89105 1.000 40.42759 ? 15  GLU   A C   1 
ATOM   107  O  O   . GLU   A 1 15  ? -38.31909 -23.17380 -9.92203  1.000 35.60481 ? 15  GLU   A O   1 
ATOM   108  C  CB  . GLU   A 1 15  ? -36.69480 -20.98293 -10.11895 1.000 35.83353 ? 15  GLU   A CB  1 
ATOM   109  C  CG  . GLU   A 1 15  ? -35.77549 -19.80512 -10.39047 1.000 42.11982 ? 15  GLU   A CG  1 
ATOM   110  C  CD  . GLU   A 1 15  ? -35.08023 -19.89224 -11.73799 1.000 51.85485 ? 15  GLU   A CD  1 
ATOM   111  O  OE1 . GLU   A 1 15  ? -34.87754 -21.01674 -12.24223 1.000 50.85224 ? 15  GLU   A OE1 1 
ATOM   112  O  OE2 . GLU   A 1 15  ? -34.72060 -18.83045 -12.28587 1.000 60.20098 ? 15  GLU   A OE2 1 
ATOM   113  N  N   . PRO   A 1 16  ? -39.48710 -22.81229 -11.80658 1.000 36.63828 ? 16  PRO   A N   1 
ATOM   114  C  CA  . PRO   A 1 16  ? -40.27093 -24.03985 -11.60092 1.000 38.76053 ? 16  PRO   A CA  1 
ATOM   115  C  C   . PRO   A 1 16  ? -39.43963 -25.31236 -11.65797 1.000 40.08846 ? 16  PRO   A C   1 
ATOM   116  O  O   . PRO   A 1 16  ? -39.87053 -26.32945 -11.10311 1.000 38.73626 ? 16  PRO   A O   1 
ATOM   117  C  CB  . PRO   A 1 16  ? -41.31174 -23.99105 -12.73228 1.000 36.80386 ? 16  PRO   A CB  1 
ATOM   118  C  CG  . PRO   A 1 16  ? -40.67100 -23.15598 -13.79607 1.000 41.85477 ? 16  PRO   A CG  1 
ATOM   119  C  CD  . PRO   A 1 16  ? -39.83563 -22.13450 -13.07029 1.000 40.61631 ? 16  PRO   A CD  1 
ATOM   120  N  N   . ALA   A 1 17  ? -38.26076 -25.29117 -12.28788 1.000 39.55781 ? 17  ALA   A N   1 
ATOM   121  C  CA  . ALA   A 1 17  ? -37.42725 -26.49122 -12.31828 1.000 37.43038 ? 17  ALA   A CA  1 
ATOM   122  C  C   . ALA   A 1 17  ? -36.92823 -26.85609 -10.92355 1.000 39.87821 ? 17  ALA   A C   1 
ATOM   123  O  O   . ALA   A 1 17  ? -36.83264 -28.04332 -10.58526 1.000 36.18370 ? 17  ALA   A O   1 
ATOM   124  C  CB  . ALA   A 1 17  ? -36.25078 -26.29695 -13.27509 1.000 39.57863 ? 17  ALA   A CB  1 
ATOM   125  N  N   . ILE   A 1 18  ? -36.60341 -25.85279 -10.10033 1.000 36.88938 ? 18  ILE   A N   1 
ATOM   126  C  CA  . ILE   A 1 18  ? -36.19771 -26.12918 -8.72252  1.000 36.90660 ? 18  ILE   A CA  1 
ATOM   127  C  C   . ILE   A 1 18  ? -37.36729 -26.69467 -7.92819  1.000 37.12470 ? 18  ILE   A C   1 
ATOM   128  O  O   . ILE   A 1 18  ? -37.20546 -27.63670 -7.14234  1.000 36.48154 ? 18  ILE   A O   1 
ATOM   129  C  CB  . ILE   A 1 18  ? -35.63470 -24.86328 -8.05513  1.000 36.27673 ? 18  ILE   A CB  1 
ATOM   130  C  CG1 . ILE   A 1 18  ? -34.52023 -24.25219 -8.90833  1.000 40.29384 ? 18  ILE   A CG1 1 
ATOM   131  C  CG2 . ILE   A 1 18  ? -35.12224 -25.18904 -6.64682  1.000 35.34152 ? 18  ILE   A CG2 1 
ATOM   132  C  CD1 . ILE   A 1 18  ? -33.95908 -22.96777 -8.33006  1.000 43.80243 ? 18  ILE   A CD1 1 
ATOM   133  N  N   . THR   A 1 19  ? -38.55828 -26.11951 -8.10944  1.000 34.70651 ? 19  THR   A N   1 
ATOM   134  C  CA  . THR   A 1 19  ? -39.75350 -26.64900 -7.46160  1.000 35.46266 ? 19  THR   A CA  1 
ATOM   135  C  C   . THR   A 1 19  ? -39.99401 -28.09922 -7.86054  1.000 37.33744 ? 19  THR   A C   1 
ATOM   136  O  O   . THR   A 1 19  ? -40.25462 -28.95153 -7.00716  1.000 32.48443 ? 19  THR   A O   1 
ATOM   137  C  CB  . THR   A 1 19  ? -40.96610 -25.79022 -7.82115  1.000 36.79051 ? 19  THR   A CB  1 
ATOM   138  O  OG1 . THR   A 1 19  ? -40.78260 -24.46627 -7.30244  1.000 35.67934 ? 19  THR   A OG1 1 
ATOM   139  C  CG2 . THR   A 1 19  ? -42.24874 -26.39800 -7.24486  1.000 31.24543 ? 19  THR   A CG2 1 
ATOM   140  N  N   . ALA   A 1 20  ? -39.91391 -28.39629 -9.16242  1.000 34.90716 ? 20  ALA   A N   1 
ATOM   141  C  CA  . ALA   A 1 20  ? -40.08041 -29.77503 -9.61423  1.000 38.32810 ? 20  ALA   A CA  1 
ATOM   142  C  C   . ALA   A 1 20  ? -39.01971 -30.68271 -9.00682  1.000 38.87460 ? 20  ALA   A C   1 
ATOM   143  O  O   . ALA   A 1 20  ? -39.31568 -31.81531 -8.60854  1.000 38.76169 ? 20  ALA   A O   1 
ATOM   144  C  CB  . ALA   A 1 20  ? -40.03221 -29.84045 -11.14087 1.000 36.92783 ? 20  ALA   A CB  1 
ATOM   145  N  N   . GLY   A 1 21  ? -37.77711 -30.20031 -8.92401  1.000 38.15354 ? 21  GLY   A N   1 
ATOM   146  C  CA  . GLY   A 1 21  ? -36.72886 -30.99116 -8.30147  1.000 36.73847 ? 21  GLY   A CA  1 
ATOM   147  C  C   . GLY   A 1 21  ? -37.00457 -31.27668 -6.83753  1.000 39.26500 ? 21  GLY   A C   1 
ATOM   148  O  O   . GLY   A 1 21  ? -36.79297 -32.39648 -6.36174  1.000 36.73455 ? 21  GLY   A O   1 
ATOM   149  N  N   . PHE   A 1 22  ? -37.47694 -30.26954 -6.10002  1.000 32.67808 ? 22  PHE   A N   1 
ATOM   150  C  CA  . PHE   A 1 22  ? -37.78171 -30.48592 -4.68738  1.000 34.08561 ? 22  PHE   A CA  1 
ATOM   151  C  C   . PHE   A 1 22  ? -38.94359 -31.45853 -4.52719  1.000 35.43851 ? 22  PHE   A C   1 
ATOM   152  O  O   . PHE   A 1 22  ? -38.92644 -32.31973 -3.63787  1.000 33.08096 ? 22  PHE   A O   1 
ATOM   153  C  CB  . PHE   A 1 22  ? -38.08809 -29.14805 -4.01343  1.000 31.17652 ? 22  PHE   A CB  1 
ATOM   154  C  CG  . PHE   A 1 22  ? -38.34226 -29.24478 -2.52876  1.000 30.09684 ? 22  PHE   A CG  1 
ATOM   155  C  CD1 . PHE   A 1 22  ? -37.52542 -30.01512 -1.71318  1.000 31.52686 ? 22  PHE   A CD1 1 
ATOM   156  C  CD2 . PHE   A 1 22  ? -39.39570 -28.54516 -1.95082  1.000 31.92777 ? 22  PHE   A CD2 1 
ATOM   157  C  CE1 . PHE   A 1 22  ? -37.75065 -30.08956 -0.34277  1.000 30.47047 ? 22  PHE   A CE1 1 
ATOM   158  C  CE2 . PHE   A 1 22  ? -39.63293 -28.61274 -0.58154  1.000 30.48192 ? 22  PHE   A CE2 1 
ATOM   159  C  CZ  . PHE   A 1 22  ? -38.80940 -29.39069 0.22306   1.000 33.15032 ? 22  PHE   A CZ  1 
ATOM   160  N  N   . LEU   A 1 23  ? -39.94822 -31.34810 -5.40015  1.000 36.11127 ? 23  LEU   A N   1 
ATOM   161  C  CA  . LEU   A 1 23  ? -41.09747 -32.24687 -5.34792  1.000 36.34149 ? 23  LEU   A CA  1 
ATOM   162  C  C   . LEU   A 1 23  ? -40.67475 -33.69085 -5.59934  1.000 41.54675 ? 23  LEU   A C   1 
ATOM   163  O  O   . LEU   A 1 23  ? -41.17153 -34.61777 -4.94509  1.000 39.21611 ? 23  LEU   A O   1 
ATOM   164  C  CB  . LEU   A 1 23  ? -42.13603 -31.80692 -6.37880  1.000 39.13519 ? 23  LEU   A CB  1 
ATOM   165  C  CG  . LEU   A 1 23  ? -42.95258 -30.54400 -6.06386  1.000 40.24607 ? 23  LEU   A CG  1 
ATOM   166  C  CD1 . LEU   A 1 23  ? -44.11095 -30.38402 -7.03943  1.000 42.51810 ? 23  LEU   A CD1 1 
ATOM   167  C  CD2 . LEU   A 1 23  ? -43.45693 -30.53827 -4.63660  1.000 40.23651 ? 23  LEU   A CD2 1 
ATOM   168  N  N   . ARG   A 1 24  ? -39.76258 -33.90422 -6.55390  1.000 35.44460 ? 24  ARG   A N   1 
ATOM   169  C  CA  . ARG   A 1 24  ? -39.24816 -35.24918 -6.78926  1.000 39.24965 ? 24  ARG   A CA  1 
ATOM   170  C  C   . ARG   A 1 24  ? -38.43795 -35.74238 -5.59597  1.000 40.83548 ? 24  ARG   A C   1 
ATOM   171  O  O   . ARG   A 1 24  ? -38.52428 -36.91874 -5.22301  1.000 43.26587 ? 24  ARG   A O   1 
ATOM   172  C  CB  . ARG   A 1 24  ? -38.40522 -35.26767 -8.06446  1.000 43.17320 ? 24  ARG   A CB  1 
ATOM   173  C  CG  . ARG   A 1 24  ? -37.66762 -36.57297 -8.31245  1.000 50.39023 ? 24  ARG   A CG  1 
ATOM   174  C  CD  . ARG   A 1 24  ? -37.06925 -36.60253 -9.71675  1.000 55.65382 ? 24  ARG   A CD  1 
ATOM   175  N  NE  . ARG   A 1 24  ? -35.64296 -36.29258 -9.69416  1.000 53.71784 ? 24  ARG   A NE  1 
ATOM   176  C  CZ  . ARG   A 1 24  ? -34.68814 -37.16434 -9.39438  1.000 64.99771 ? 24  ARG   A CZ  1 
ATOM   177  N  NH1 . ARG   A 1 24  ? -34.96555 -38.43219 -9.13312  1.000 70.37461 ? 24  ARG   A NH1 1 
ATOM   178  N  NH2 . ARG   A 1 24  ? -33.42134 -36.75563 -9.36250  1.000 56.70411 ? 24  ARG   A NH2 1 
ATOM   179  N  N   . PHE   A 1 25  ? -37.63687 -34.85732 -4.99281  1.000 37.56141 ? 25  PHE   A N   1 
ATOM   180  C  CA  . PHE   A 1 25  ? -36.88780 -35.21718 -3.79252  1.000 37.38944 ? 25  PHE   A CA  1 
ATOM   181  C  C   . PHE   A 1 25  ? -37.82690 -35.65392 -2.67439  1.000 39.92923 ? 25  PHE   A C   1 
ATOM   182  O  O   . PHE   A 1 25  ? -37.57503 -36.65671 -1.99480  1.000 40.73413 ? 25  PHE   A O   1 
ATOM   183  C  CB  . PHE   A 1 25  ? -36.03055 -34.02884 -3.35036  1.000 38.10842 ? 25  PHE   A CB  1 
ATOM   184  C  CG  . PHE   A 1 25  ? -35.42085 -34.17660 -1.97748  1.000 36.77929 ? 25  PHE   A CG  1 
ATOM   185  C  CD1 . PHE   A 1 25  ? -34.21506 -34.84739 -1.80885  1.000 37.97638 ? 25  PHE   A CD1 1 
ATOM   186  C  CD2 . PHE   A 1 25  ? -36.03269 -33.61199 -0.86488  1.000 32.52724 ? 25  PHE   A CD2 1 
ATOM   187  C  CE1 . PHE   A 1 25  ? -33.63996 -34.97710 -0.54722  1.000 37.25599 ? 25  PHE   A CE1 1 
ATOM   188  C  CE2 . PHE   A 1 25  ? -35.47195 -33.73510 0.39684   1.000 34.12831 ? 25  PHE   A CE2 1 
ATOM   189  C  CZ  . PHE   A 1 25  ? -34.27215 -34.41849 0.55965   1.000 38.30581 ? 25  PHE   A CZ  1 
ATOM   190  N  N   . LEU   A 1 26  ? -38.92366 -34.91657 -2.48064  1.000 36.06679 ? 26  LEU   A N   1 
ATOM   191  C  CA  . LEU   A 1 26  ? -39.86800 -35.24030 -1.41603  1.000 40.05327 ? 26  LEU   A CA  1 
ATOM   192  C  C   . LEU   A 1 26  ? -40.59128 -36.55267 -1.68752  1.000 42.31632 ? 26  LEU   A C   1 
ATOM   193  O  O   . LEU   A 1 26  ? -40.89714 -37.29931 -0.75216  1.000 41.49171 ? 26  LEU   A O   1 
ATOM   194  C  CB  . LEU   A 1 26  ? -40.88249 -34.10913 -1.25283  1.000 35.41643 ? 26  LEU   A CB  1 
ATOM   195  C  CG  . LEU   A 1 26  ? -40.38579 -32.80672 -0.63362  1.000 32.46284 ? 26  LEU   A CG  1 
ATOM   196  C  CD1 . LEU   A 1 26  ? -41.54638 -31.82802 -0.50767  1.000 35.21626 ? 26  LEU   A CD1 1 
ATOM   197  C  CD2 . LEU   A 1 26  ? -39.73830 -33.05851 0.71673   1.000 31.55455 ? 26  LEU   A CD2 1 
ATOM   198  N  N   . GLN   A 1 27  ? -40.89521 -36.84047 -2.95793  1.000 41.81130 ? 27  GLN   A N   1 
ATOM   199  C  CA  . GLN   A 1 27  ? -41.61078 -38.06276 -3.30270  1.000 45.91525 ? 27  GLN   A CA  1 
ATOM   200  C  C   . GLN   A 1 27  ? -40.72231 -39.29559 -3.25719  1.000 43.88069 ? 27  GLN   A C   1 
ATOM   201  O  O   . GLN   A 1 27  ? -41.23725 -40.40470 -3.08856  1.000 48.77559 ? 27  GLN   A O   1 
ATOM   202  C  CB  . GLN   A 1 27  ? -42.23251 -37.94560 -4.69835  1.000 45.64448 ? 27  GLN   A CB  1 
ATOM   203  C  CG  . GLN   A 1 27  ? -43.61480 -37.32152 -4.71080  1.000 55.82028 ? 27  GLN   A CG  1 
ATOM   204  N  N   . GLY   A 1 28  ? -39.41129 -39.13321 -3.40565  1.000 39.71427 ? 28  GLY   A N   1 
ATOM   205  C  CA  . GLY   A 1 28  ? -38.52460 -40.27537 -3.44368  1.000 44.17522 ? 28  GLY   A CA  1 
ATOM   206  C  C   . GLY   A 1 28  ? -37.65176 -40.40699 -2.21571  1.000 45.53420 ? 28  GLY   A C   1 
ATOM   207  O  O   . GLY   A 1 28  ? -37.96422 -41.17064 -1.29759  1.000 50.80124 ? 28  GLY   A O   1 
ATOM   208  N  N   . GLU   A 1 29  ? -36.56663 -39.63366 -2.18441  1.000 47.56497 ? 29  GLU   A N   1 
ATOM   209  C  CA  . GLU   A 1 29  ? -35.54693 -39.79350 -1.15196  1.000 48.60166 ? 29  GLU   A CA  1 
ATOM   210  C  C   . GLU   A 1 29  ? -36.11003 -39.54619 0.24574   1.000 46.07082 ? 29  GLU   A C   1 
ATOM   211  O  O   . GLU   A 1 29  ? -35.88990 -40.34189 1.16585   1.000 40.83078 ? 29  GLU   A O   1 
ATOM   212  C  CB  . GLU   A 1 29  ? -34.38267 -38.84419 -1.43968  1.000 48.39649 ? 29  GLU   A CB  1 
ATOM   213  C  CG  . GLU   A 1 29  ? -33.22374 -38.97423 -0.47214  1.000 54.77257 ? 29  GLU   A CG  1 
ATOM   214  C  CD  . GLU   A 1 29  ? -32.25911 -40.07495 -0.86795  1.000 58.96830 ? 29  GLU   A CD  1 
ATOM   215  O  OE1 . GLU   A 1 29  ? -32.00739 -40.23147 -2.08184  1.000 62.01215 ? 29  GLU   A OE1 1 
ATOM   216  O  OE2 . GLU   A 1 29  ? -31.75708 -40.78024 0.03460   1.000 58.72865 ? 29  GLU   A OE2 1 
ATOM   217  N  N   . ALA   A 1 30  ? -36.84596 -38.44591 0.42325   1.000 44.97020 ? 30  ALA   A N   1 
ATOM   218  C  CA  . ALA   A 1 30  ? -37.25176 -38.04000 1.76610   1.000 39.35553 ? 30  ALA   A CA  1 
ATOM   219  C  C   . ALA   A 1 30  ? -38.17366 -39.06299 2.42230   1.000 40.04200 ? 30  ALA   A C   1 
ATOM   220  O  O   . ALA   A 1 30  ? -38.18941 -39.18146 3.65222   1.000 36.18021 ? 30  ALA   A O   1 
ATOM   221  C  CB  . ALA   A 1 30  ? -37.92761 -36.67258 1.71506   1.000 36.27046 ? 30  ALA   A CB  1 
ATOM   222  N  N   . ARG   A 1 31  ? -38.93502 -39.81723 1.62611   1.000 38.10376 ? 31  ARG   A N   1 
ATOM   223  C  CA  . ARG   A 1 31  ? -39.85860 -40.79565 2.18869   1.000 40.49425 ? 31  ARG   A CA  1 
ATOM   224  C  C   . ARG   A 1 31  ? -39.14126 -41.92840 2.91007   1.000 43.01713 ? 31  ARG   A C   1 
ATOM   225  O  O   . ARG   A 1 31  ? -39.74918 -42.59282 3.75409   1.000 44.59672 ? 31  ARG   A O   1 
ATOM   226  C  CB  . ARG   A 1 31  ? -40.73939 -41.37973 1.08671   1.000 41.85302 ? 31  ARG   A CB  1 
ATOM   227  C  CG  . ARG   A 1 31  ? -41.46331 -40.33840 0.27706   1.000 48.18744 ? 31  ARG   A CG  1 
ATOM   228  C  CD  . ARG   A 1 31  ? -42.66394 -39.82198 1.02522   1.000 49.68298 ? 31  ARG   A CD  1 
ATOM   229  N  NE  . ARG   A 1 31  ? -43.41165 -38.85865 0.23050   1.000 51.89764 ? 31  ARG   A NE  1 
ATOM   230  C  CZ  . ARG   A 1 31  ? -44.67743 -39.02895 -0.12467  1.000 50.47916 ? 31  ARG   A CZ  1 
ATOM   231  N  NH1 . ARG   A 1 31  ? -45.34440 -40.12562 0.20493   1.000 41.22684 ? 31  ARG   A NH1 1 
ATOM   232  N  NH2 . ARG   A 1 31  ? -45.28152 -38.08758 -0.84558  1.000 47.31537 ? 31  ARG   A NH2 1 
ATOM   233  N  N   . GLN   A 1 32  ? -37.87396 -42.17411 2.59203   1.000 42.30869 ? 32  GLN   A N   1 
ATOM   234  C  CA  . GLN   A 1 32  ? -37.11293 -43.24107 3.22631   1.000 44.99413 ? 32  GLN   A CA  1 
ATOM   235  C  C   . GLN   A 1 32  ? -36.29575 -42.76279 4.41767   1.000 44.75296 ? 32  GLN   A C   1 
ATOM   236  O  O   . GLN   A 1 32  ? -35.61951 -43.57742 5.05098   1.000 39.88013 ? 32  GLN   A O   1 
ATOM   237  C  CB  . GLN   A 1 32  ? -36.18308 -43.89982 2.20418   1.000 48.41395 ? 32  GLN   A CB  1 
ATOM   238  C  CG  . GLN   A 1 32  ? -36.84128 -44.19263 0.86925   1.000 52.78681 ? 32  GLN   A CG  1 
ATOM   239  C  CD  . GLN   A 1 32  ? -38.02328 -45.13102 0.99954   1.000 63.52022 ? 32  GLN   A CD  1 
ATOM   240  O  OE1 . GLN   A 1 32  ? -38.01378 -46.05179 1.81960   1.000 66.16254 ? 32  GLN   A OE1 1 
ATOM   241  N  NE2 . GLN   A 1 32  ? -39.04937 -44.90728 0.18342   1.000 67.53241 ? 32  GLN   A NE2 1 
ATOM   242  N  N   . ALA   A 1 33  ? -36.35359 -41.47803 4.74844   1.000 39.99537 ? 33  ALA   A N   1 
ATOM   243  C  CA  . ALA   A 1 33  ? -35.48286 -40.92392 5.77291   1.000 38.33599 ? 33  ALA   A CA  1 
ATOM   244  C  C   . ALA   A 1 33  ? -36.06101 -41.14346 7.16536   1.000 40.89289 ? 33  ALA   A C   1 
ATOM   245  O  O   . ALA   A 1 33  ? -37.27399 -41.29220 7.34156   1.000 38.57656 ? 33  ALA   A O   1 
ATOM   246  C  CB  . ALA   A 1 33  ? -35.26524 -39.42831 5.53322   1.000 32.56341 ? 33  ALA   A CB  1 
ATOM   247  N  N   . ASP   A 1 34  ? -35.16505 -41.19578 8.15960   1.000 38.14717 ? 34  ASP   A N   1 
ATOM   248  C  CA  . ASP   A 1 34  ? -35.59692 -41.11397 9.55240   1.000 34.90448 ? 34  ASP   A CA  1 
ATOM   249  C  C   . ASP   A 1 34  ? -36.17179 -39.74088 9.87427   1.000 38.36218 ? 34  ASP   A C   1 
ATOM   250  O  O   . ASP   A 1 34  ? -37.08271 -39.63027 10.70328  1.000 35.67404 ? 34  ASP   A O   1 
ATOM   251  C  CB  . ASP   A 1 34  ? -34.43500 -41.41933 10.50487  1.000 34.98953 ? 34  ASP   A CB  1 
ATOM   252  C  CG  . ASP   A 1 34  ? -33.87653 -42.82144 10.32650  1.000 32.91459 ? 34  ASP   A CG  1 
ATOM   253  O  OD1 . ASP   A 1 34  ? -34.65129 -43.73524 9.99420   1.000 39.48224 ? 34  ASP   A OD1 1 
ATOM   254  O  OD2 . ASP   A 1 34  ? -32.66370 -43.01203 10.53233  1.000 41.15938 ? 34  ASP   A OD2 1 
ATOM   255  N  N   . ALA   A 1 35  ? -35.65344 -38.69163 9.23905   1.000 35.63712 ? 35  ALA   A N   1 
ATOM   256  C  CA  . ALA   A 1 35  ? -36.09334 -37.32629 9.49184   1.000 33.94061 ? 35  ALA   A CA  1 
ATOM   257  C  C   . ALA   A 1 35  ? -35.52877 -36.42459 8.40495   1.000 34.95383 ? 35  ALA   A C   1 
ATOM   258  O  O   . ALA   A 1 35  ? -34.49432 -36.72558 7.80152   1.000 33.77610 ? 35  ALA   A O   1 
ATOM   259  C  CB  . ALA   A 1 35  ? -35.64525 -36.83358 10.87457  1.000 35.25845 ? 35  ALA   A CB  1 
ATOM   260  N  N   . LEU   A 1 36  ? -36.20685 -35.29984 8.18561   1.000 30.00319 ? 36  LEU   A N   1 
ATOM   261  C  CA  . LEU   A 1 36  ? -35.79016 -34.29778 7.20822   1.000 34.23221 ? 36  LEU   A CA  1 
ATOM   262  C  C   . LEU   A 1 36  ? -35.68562 -32.94945 7.90161   1.000 32.53135 ? 36  LEU   A C   1 
ATOM   263  O  O   . LEU   A 1 36  ? -36.65270 -32.48682 8.51632   1.000 30.94673 ? 36  LEU   A O   1 
ATOM   264  C  CB  . LEU   A 1 36  ? -36.76809 -34.20912 6.02977   1.000 31.78573 ? 36  LEU   A CB  1 
ATOM   265  C  CG  . LEU   A 1 36  ? -36.49920 -33.05561 5.05110   1.000 33.80280 ? 36  LEU   A CG  1 
ATOM   266  C  CD1 . LEU   A 1 36  ? -35.13165 -33.19948 4.38166   1.000 30.14720 ? 36  LEU   A CD1 1 
ATOM   267  C  CD2 . LEU   A 1 36  ? -37.60411 -32.96714 4.00404   1.000 30.33955 ? 36  LEU   A CD2 1 
ATOM   268  N  N   . TYR   A 1 37  ? -34.51347 -32.32840 7.80833   1.000 28.56001 ? 37  TYR   A N   1 
ATOM   269  C  CA  . TYR   A 1 37  ? -34.26806 -31.00519 8.35978   1.000 30.98811 ? 37  TYR   A CA  1 
ATOM   270  C  C   . TYR   A 1 37  ? -34.01965 -30.02705 7.22229   1.000 33.29645 ? 37  TYR   A C   1 
ATOM   271  O  O   . TYR   A 1 37  ? -33.15574 -30.26448 6.37156   1.000 30.86247 ? 37  TYR   A O   1 
ATOM   272  C  CB  . TYR   A 1 37  ? -33.05829 -31.01594 9.29730   1.000 30.38660 ? 37  TYR   A CB  1 
ATOM   273  C  CG  . TYR   A 1 37  ? -33.29880 -31.72016 10.61029  1.000 35.43145 ? 37  TYR   A CG  1 
ATOM   274  C  CD1 . TYR   A 1 37  ? -33.28984 -33.11167 10.68454  1.000 31.18609 ? 37  TYR   A CD1 1 
ATOM   275  C  CD2 . TYR   A 1 37  ? -33.51755 -30.99627 11.78082  1.000 33.05238 ? 37  TYR   A CD2 1 
ATOM   276  C  CE1 . TYR   A 1 37  ? -33.50413 -33.76542 11.88445  1.000 32.11384 ? 37  TYR   A CE1 1 
ATOM   277  C  CE2 . TYR   A 1 37  ? -33.73638 -31.64249 12.98706  1.000 35.19905 ? 37  TYR   A CE2 1 
ATOM   278  C  CZ  . TYR   A 1 37  ? -33.72793 -33.02800 13.03101  1.000 38.59834 ? 37  TYR   A CZ  1 
ATOM   279  O  OH  . TYR   A 1 37  ? -33.93316 -33.68138 14.22668  1.000 38.26669 ? 37  TYR   A OH  1 
ATOM   280  N  N   . ILE   A 1 38  ? -34.74640 -28.92062 7.22867   1.000 29.76448 ? 38  ILE   A N   1 
ATOM   281  C  CA  . ILE   A 1 38  ? -34.57478 -27.85877 6.24705   1.000 29.38279 ? 38  ILE   A CA  1 
ATOM   282  C  C   . ILE   A 1 38  ? -33.95946 -26.67474 6.97871   1.000 32.89467 ? 38  ILE   A C   1 
ATOM   283  O  O   . ILE   A 1 38  ? -34.62919 -26.00696 7.77874   1.000 30.22723 ? 38  ILE   A O   1 
ATOM   284  C  CB  . ILE   A 1 38  ? -35.90238 -27.49522 5.56969   1.000 31.28553 ? 38  ILE   A CB  1 
ATOM   285  C  CG1 . ILE   A 1 38  ? -36.58468 -28.77351 5.06406   1.000 32.44186 ? 38  ILE   A CG1 1 
ATOM   286  C  CG2 . ILE   A 1 38  ? -35.67429 -26.50539 4.42450   1.000 30.64410 ? 38  ILE   A CG2 1 
ATOM   287  C  CD1 . ILE   A 1 38  ? -37.84765 -28.53239 4.26169   1.000 27.14207 ? 38  ILE   A CD1 1 
ATOM   288  N  N   . LEU   A 1 39  ? -32.67747 -26.42214 6.72258   1.000 28.54046 ? 39  LEU   A N   1 
ATOM   289  C  CA  . LEU   A 1 39  ? -31.93511 -25.40609 7.47237   1.000 29.73366 ? 39  LEU   A CA  1 
ATOM   290  C  C   . LEU   A 1 39  ? -32.00071 -24.03046 6.81260   1.000 32.22903 ? 39  LEU   A C   1 
ATOM   291  O  O   . LEU   A 1 39  ? -30.98246 -23.35736 6.63992   1.000 29.70159 ? 39  LEU   A O   1 
ATOM   292  C  CB  . LEU   A 1 39  ? -30.48724 -25.85043 7.65770   1.000 31.52261 ? 39  LEU   A CB  1 
ATOM   293  C  CG  . LEU   A 1 39  ? -30.28211 -27.24130 8.26503   1.000 34.02479 ? 39  LEU   A CG  1 
ATOM   294  C  CD1 . LEU   A 1 39  ? -28.79796 -27.49920 8.55541   1.000 33.26783 ? 39  LEU   A CD1 1 
ATOM   295  C  CD2 . LEU   A 1 39  ? -31.13374 -27.41068 9.52298   1.000 28.41799 ? 39  LEU   A CD2 1 
ATOM   296  N  N   . GLY   A 1 40  ? -33.19558 -23.58785 6.43918   1.000 30.68382 ? 40  GLY   A N   1 
ATOM   297  C  CA  . GLY   A 1 40  ? -33.36204 -22.19387 6.08189   1.000 29.31015 ? 40  GLY   A CA  1 
ATOM   298  C  C   . GLY   A 1 40  ? -33.25989 -21.94437 4.58714   1.000 34.10679 ? 40  GLY   A C   1 
ATOM   299  O  O   . GLY   A 1 40  ? -32.67645 -22.72409 3.82532   1.000 31.00819 ? 40  GLY   A O   1 
ATOM   300  N  N   . ASP   A 1 41  ? -33.83701 -20.81191 4.17828   1.000 31.20596 ? 41  ASP   A N   1 
ATOM   301  C  CA  . ASP   A 1 41  ? -33.90638 -20.39411 2.77661   1.000 30.43476 ? 41  ASP   A CA  1 
ATOM   302  C  C   . ASP   A 1 41  ? -34.57320 -21.45873 1.91259   1.000 31.50477 ? 41  ASP   A C   1 
ATOM   303  O  O   . ASP   A 1 41  ? -34.14327 -21.74403 0.78974   1.000 30.09535 ? 41  ASP   A O   1 
ATOM   304  C  CB  . ASP   A 1 41  ? -32.52518 -20.02421 2.23791   1.000 32.56869 ? 41  ASP   A CB  1 
ATOM   305  C  CG  . ASP   A 1 41  ? -32.05375 -18.68413 2.75335   1.000 38.19051 ? 41  ASP   A CG  1 
ATOM   306  O  OD1 . ASP   A 1 41  ? -32.76370 -18.07773 3.59114   1.000 38.62807 ? 41  ASP   A OD1 1 
ATOM   307  O  OD2 . ASP   A 1 41  ? -30.98635 -18.22747 2.31334   1.000 37.58418 ? 41  ASP   A OD2 1 
ATOM   308  N  N   . LEU   A 1 42  ? -35.63574 -22.05960 2.45017   1.000 29.81638 ? 42  LEU   A N   1 
ATOM   309  C  CA  . LEU   A 1 42  ? -36.50214 -22.88111 1.61797   1.000 28.01642 ? 42  LEU   A CA  1 
ATOM   310  C  C   . LEU   A 1 42  ? -37.14018 -22.03647 0.52578   1.000 30.91107 ? 42  LEU   A C   1 
ATOM   311  O  O   . LEU   A 1 42  ? -37.20889 -22.45231 -0.63677  1.000 29.47900 ? 42  LEU   A O   1 
ATOM   312  C  CB  . LEU   A 1 42  ? -37.57222 -23.55491 2.48303   1.000 29.71015 ? 42  LEU   A CB  1 
ATOM   313  C  CG  . LEU   A 1 42  ? -38.64708 -24.39144 1.77953   1.000 33.55777 ? 42  LEU   A CG  1 
ATOM   314  C  CD1 . LEU   A 1 42  ? -38.01830 -25.50284 0.93831   1.000 29.12945 ? 42  LEU   A CD1 1 
ATOM   315  C  CD2 . LEU   A 1 42  ? -39.62149 -24.97589 2.80091   1.000 32.02139 ? 42  LEU   A CD2 1 
ATOM   316  N  N   . PHE   A 1 43  ? -37.58340 -20.83262 0.87850   1.000 29.46964 ? 43  PHE   A N   1 
ATOM   317  C  CA  . PHE   A 1 43  ? -38.19871 -19.90318 -0.05166  1.000 29.37945 ? 43  PHE   A CA  1 
ATOM   318  C  C   . PHE   A 1 43  ? -37.29272 -18.69889 -0.27506  1.000 32.14552 ? 43  PHE   A C   1 
ATOM   319  O  O   . PHE   A 1 43  ? -36.54266 -18.28528 0.61593   1.000 31.60040 ? 43  PHE   A O   1 
ATOM   320  C  CB  . PHE   A 1 43  ? -39.57641 -19.45744 0.46142   1.000 29.36119 ? 43  PHE   A CB  1 
ATOM   321  C  CG  . PHE   A 1 43  ? -40.55531 -20.59423 0.59415   1.000 30.42576 ? 43  PHE   A CG  1 
ATOM   322  C  CD1 . PHE   A 1 43  ? -41.24379 -21.06599 -0.51607  1.000 31.31229 ? 43  PHE   A CD1 1 
ATOM   323  C  CD2 . PHE   A 1 43  ? -40.76672 -21.20734 1.81947   1.000 30.76337 ? 43  PHE   A CD2 1 
ATOM   324  C  CE1 . PHE   A 1 43  ? -42.14757 -22.11917 -0.39918  1.000 31.47990 ? 43  PHE   A CE1 1 
ATOM   325  C  CE2 . PHE   A 1 43  ? -41.66322 -22.26568 1.94088   1.000 30.30287 ? 43  PHE   A CE2 1 
ATOM   326  C  CZ  . PHE   A 1 43  ? -42.34758 -22.71957 0.83340   1.000 28.94482 ? 43  PHE   A CZ  1 
ATOM   327  N  N   . GLU   A 1 44  ? -37.35353 -18.15744 -1.49555  1.000 29.89855 ? 44  GLU   A N   1 
ATOM   328  C  CA  . GLU   A 1 44  ? -36.58996 -16.96395 -1.84084  1.000 33.56352 ? 44  GLU   A CA  1 
ATOM   329  C  C   . GLU   A 1 44  ? -37.08980 -15.72978 -1.10223  1.000 36.02167 ? 44  GLU   A C   1 
ATOM   330  O  O   . GLU   A 1 44  ? -36.32962 -14.76586 -0.92775  1.000 33.65029 ? 44  GLU   A O   1 
ATOM   331  C  CB  . GLU   A 1 44  ? -36.65130 -16.74145 -3.35734  1.000 36.82509 ? 44  GLU   A CB  1 
ATOM   332  C  CG  . GLU   A 1 44  ? -35.98954 -15.46247 -3.88027  1.000 42.91176 ? 44  GLU   A CG  1 
ATOM   333  C  CD  . GLU   A 1 44  ? -34.48372 -15.41797 -3.67851  1.000 47.50159 ? 44  GLU   A CD  1 
ATOM   334  O  OE1 . GLU   A 1 44  ? -33.89030 -16.43250 -3.25005  1.000 52.47028 ? 44  GLU   A OE1 1 
ATOM   335  O  OE2 . GLU   A 1 44  ? -33.88894 -14.35403 -3.95117  1.000 53.78060 ? 44  GLU   A OE2 1 
ATOM   336  N  N   . ALA   A 1 45  ? -38.34464 -15.73727 -0.66297  1.000 33.11940 ? 45  ALA   A N   1 
ATOM   337  C  CA  . ALA   A 1 45  ? -38.90291 -14.60649 0.06027   1.000 33.15398 ? 45  ALA   A CA  1 
ATOM   338  C  C   . ALA   A 1 45  ? -40.09432 -15.09829 0.86443   1.000 37.03275 ? 45  ALA   A C   1 
ATOM   339  O  O   . ALA   A 1 45  ? -40.71704 -16.10707 0.52453   1.000 33.64098 ? 45  ALA   A O   1 
ATOM   340  C  CB  . ALA   A 1 45  ? -39.30930 -13.47700 -0.89646  1.000 35.41124 ? 45  ALA   A CB  1 
ATOM   341  N  N   . TRP   A 1 46  ? -40.39995 -14.37925 1.94326   1.000 34.00735 ? 46  TRP   A N   1 
ATOM   342  C  CA  . TRP   A 1 46  ? -41.58787 -14.67350 2.73833   1.000 31.73275 ? 46  TRP   A CA  1 
ATOM   343  C  C   . TRP   A 1 46  ? -42.02982 -13.39386 3.42239   1.000 34.27505 ? 46  TRP   A C   1 
ATOM   344  O  O   . TRP   A 1 46  ? -41.22251 -12.74407 4.09394   1.000 33.65172 ? 46  TRP   A O   1 
ATOM   345  C  CB  . TRP   A 1 46  ? -41.32283 -15.76243 3.78303   1.000 30.40101 ? 46  TRP   A CB  1 
ATOM   346  C  CG  . TRP   A 1 46  ? -42.56789 -16.47659 4.28343   1.000 30.62299 ? 46  TRP   A CG  1 
ATOM   347  C  CD1 . TRP   A 1 46  ? -43.32385 -16.15357 5.37636   1.000 32.80011 ? 46  TRP   A CD1 1 
ATOM   348  C  CD2 . TRP   A 1 46  ? -43.16948 -17.65236 3.71570   1.000 30.06883 ? 46  TRP   A CD2 1 
ATOM   349  N  NE1 . TRP   A 1 46  ? -44.36758 -17.04885 5.51392   1.000 29.14482 ? 46  TRP   A NE1 1 
ATOM   350  C  CE2 . TRP   A 1 46  ? -44.29122 -17.97674 4.50875   1.000 30.34292 ? 46  TRP   A CE2 1 
ATOM   351  C  CE3 . TRP   A 1 46  ? -42.86458 -18.46054 2.61472   1.000 31.65456 ? 46  TRP   A CE3 1 
ATOM   352  C  CZ2 . TRP   A 1 46  ? -45.10881 -19.07579 4.23510   1.000 33.88651 ? 46  TRP   A CZ2 1 
ATOM   353  C  CZ3 . TRP   A 1 46  ? -43.67723 -19.55167 2.34301   1.000 31.11975 ? 46  TRP   A CZ3 1 
ATOM   354  C  CH2 . TRP   A 1 46  ? -44.78503 -19.85015 3.15223   1.000 32.12328 ? 46  TRP   A CH2 1 
ATOM   355  N  N   . ILE   A 1 47  ? -43.30428 -13.03751 3.24658   1.000 32.95498 ? 47  ILE   A N   1 
ATOM   356  C  CA  . ILE   A 1 47  ? -43.87539 -11.83167 3.82865   1.000 32.61547 ? 47  ILE   A CA  1 
ATOM   357  C  C   . ILE   A 1 47  ? -44.99561 -12.14693 4.81290   1.000 33.35130 ? 47  ILE   A C   1 
ATOM   358  O  O   . ILE   A 1 47  ? -45.63816 -11.23072 5.32766   1.000 34.42246 ? 47  ILE   A O   1 
ATOM   359  C  CB  . ILE   A 1 47  ? -44.35788 -10.85674 2.73526   1.000 31.19868 ? 47  ILE   A CB  1 
ATOM   360  C  CG1 . ILE   A 1 47  ? -45.43959 -11.50636 1.86219   1.000 36.37623 ? 47  ILE   A CG1 1 
ATOM   361  C  CG2 . ILE   A 1 47  ? -43.17619 -10.37263 1.89654   1.000 31.56790 ? 47  ILE   A CG2 1 
ATOM   362  C  CD1 . ILE   A 1 47  ? -46.24504 -10.51249 1.04543   1.000 41.94320 ? 47  ILE   A CD1 1 
ATOM   363  N  N   . GLY   A 1 48  ? -45.23262 -13.42164 5.09516   1.000 32.89243 ? 48  GLY   A N   1 
ATOM   364  C  CA  . GLY   A 1 48  ? -46.21677 -13.83741 6.08119   1.000 33.33063 ? 48  GLY   A CA  1 
ATOM   365  C  C   . GLY   A 1 48  ? -46.98747 -15.06272 5.62503   1.000 35.55180 ? 48  GLY   A C   1 
ATOM   366  O  O   . GLY   A 1 48  ? -47.12971 -15.33382 4.43086   1.000 33.65015 ? 48  GLY   A O   1 
ATOM   367  N  N   . ASP   A 1 49  ? -47.50822 -15.81658 6.59820   1.000 32.05596 ? 49  ASP   A N   1 
ATOM   368  C  CA  . ASP   A 1 49  ? -48.21653 -17.06030 6.31325   1.000 35.96348 ? 49  ASP   A CA  1 
ATOM   369  C  C   . ASP   A 1 49  ? -49.57939 -16.84461 5.66616   1.000 37.16085 ? 49  ASP   A C   1 
ATOM   370  O  O   . ASP   A 1 49  ? -50.16395 -17.81531 5.17602   1.000 37.49099 ? 49  ASP   A O   1 
ATOM   371  C  CB  . ASP   A 1 49  ? -48.41576 -17.87254 7.59283   1.000 32.37203 ? 49  ASP   A CB  1 
ATOM   372  C  CG  . ASP   A 1 49  ? -47.11310 -18.38996 8.17970   1.000 37.22123 ? 49  ASP   A CG  1 
ATOM   373  O  OD1 . ASP   A 1 49  ? -46.04569 -18.26751 7.53635   1.000 36.01193 ? 49  ASP   A OD1 1 
ATOM   374  O  OD2 . ASP   A 1 49  ? -47.17053 -18.93922 9.29450   1.000 35.83850 ? 49  ASP   A OD2 1 
ATOM   375  N  N   . ASP   A 1 50  ? -50.11483 -15.62497 5.67835   1.000 33.60185 ? 50  ASP   A N   1 
ATOM   376  C  CA  . ASP   A 1 50  ? -51.38803 -15.34512 5.02214   1.000 33.44528 ? 50  ASP   A CA  1 
ATOM   377  C  C   . ASP   A 1 50  ? -51.22875 -15.03729 3.53777   1.000 35.27042 ? 50  ASP   A C   1 
ATOM   378  O  O   . ASP   A 1 50  ? -52.22633 -14.77127 2.86012   1.000 34.87389 ? 50  ASP   A O   1 
ATOM   379  C  CB  . ASP   A 1 50  ? -52.10755 -14.19248 5.73444   1.000 33.71465 ? 50  ASP   A CB  1 
ATOM   380  C  CG  . ASP   A 1 50  ? -51.26171 -12.93030 5.81982   1.000 39.68300 ? 50  ASP   A CG  1 
ATOM   381  O  OD1 . ASP   A 1 50  ? -50.01935 -13.02226 5.74749   1.000 36.90999 ? 50  ASP   A OD1 1 
ATOM   382  O  OD2 . ASP   A 1 50  ? -51.84079 -11.84145 5.98172   1.000 40.10689 ? 50  ASP   A OD2 1 
ATOM   383  N  N   . ASP   A 1 51  ? -50.00741 -15.08179 3.02344   1.000 32.44979 ? 51  ASP   A N   1 
ATOM   384  C  CA  . ASP   A 1 51  ? -49.73726 -14.88979 1.60621   1.000 32.85057 ? 51  ASP   A CA  1 
ATOM   385  C  C   . ASP   A 1 51  ? -50.42635 -15.98698 0.79807   1.000 34.80456 ? 51  ASP   A C   1 
ATOM   386  O  O   . ASP   A 1 51  ? -50.16790 -17.17534 1.03906   1.000 32.02818 ? 51  ASP   A O   1 
ATOM   387  C  CB  . ASP   A 1 51  ? -48.21742 -14.90401 1.40132   1.000 33.38630 ? 51  ASP   A CB  1 
ATOM   388  C  CG  . ASP   A 1 51  ? -47.78930 -14.59162 -0.02679  1.000 36.56341 ? 51  ASP   A CG  1 
ATOM   389  O  OD1 . ASP   A 1 51  ? -48.63438 -14.59041 -0.94316  1.000 32.98574 ? 51  ASP   A OD1 1 
ATOM   390  O  OD2 . ASP   A 1 51  ? -46.57425 -14.35217 -0.22735  1.000 36.40411 ? 51  ASP   A OD2 1 
ATOM   391  N  N   . PRO   A 1 52  ? -51.31567 -15.65045 -0.13704  1.000 35.63326 ? 52  PRO   A N   1 
ATOM   392  C  CA  . PRO   A 1 52  ? -52.02724 -16.68439 -0.89980  1.000 35.04540 ? 52  PRO   A CA  1 
ATOM   393  C  C   . PRO   A 1 52  ? -51.24721 -17.27524 -2.06480  1.000 37.69720 ? 52  PRO   A C   1 
ATOM   394  O  O   . PRO   A 1 52  ? -51.83477 -18.03489 -2.84031  1.000 34.44683 ? 52  PRO   A O   1 
ATOM   395  C  CB  . PRO   A 1 52  ? -53.27054 -15.93379 -1.40852  1.000 34.05670 ? 52  PRO   A CB  1 
ATOM   396  C  CG  . PRO   A 1 52  ? -52.80953 -14.52714 -1.55012  1.000 39.60817 ? 52  PRO   A CG  1 
ATOM   397  C  CD  . PRO   A 1 52  ? -51.83494 -14.29942 -0.41459  1.000 35.48737 ? 52  PRO   A CD  1 
ATOM   398  N  N   . ASN   A 1 53  ? -49.95778 -16.93589 -2.22079  1.000 32.37678 ? 53  ASN   A N   1 
ATOM   399  C  CA  . ASN   A 1 53  ? -49.08522 -17.49887 -3.24949  1.000 32.54497 ? 53  ASN   A CA  1 
ATOM   400  C  C   . ASN   A 1 53  ? -49.30850 -19.00538 -3.34903  1.000 32.24365 ? 53  ASN   A C   1 
ATOM   401  O  O   . ASN   A 1 53  ? -49.03859 -19.73196 -2.38755  1.000 31.64717 ? 53  ASN   A O   1 
ATOM   402  C  CB  . ASN   A 1 53  ? -47.61873 -17.18708 -2.92720  1.000 32.85147 ? 53  ASN   A CB  1 
ATOM   403  C  CG  . ASN   A 1 53  ? -46.66058 -17.61009 -4.03276  1.000 38.49992 ? 53  ASN   A CG  1 
ATOM   404  O  OD1 . ASN   A 1 53  ? -47.01555 -18.37279 -4.92645  1.000 35.60627 ? 53  ASN   A OD1 1 
ATOM   405  N  ND2 . ASN   A 1 53  ? -45.42752 -17.11253 -3.96601  1.000 36.63892 ? 53  ASN   A ND2 1 
ATOM   406  N  N   . PRO   A 1 54  ? -49.81895 -19.50384 -4.48313  1.000 32.10832 ? 54  PRO   A N   1 
ATOM   407  C  CA  . PRO   A 1 54  ? -50.12221 -20.94169 -4.58271  1.000 32.67762 ? 54  PRO   A CA  1 
ATOM   408  C  C   . PRO   A 1 54  ? -48.91234 -21.83895 -4.40722  1.000 33.40964 ? 54  PRO   A C   1 
ATOM   409  O  O   . PRO   A 1 54  ? -49.07224 -22.97620 -3.94806  1.000 30.72206 ? 54  PRO   A O   1 
ATOM   410  C  CB  . PRO   A 1 54  ? -50.72253 -21.07638 -5.99035  1.000 34.39858 ? 54  PRO   A CB  1 
ATOM   411  C  CG  . PRO   A 1 54  ? -51.26383 -19.71102 -6.30625  1.000 35.18224 ? 54  PRO   A CG  1 
ATOM   412  C  CD  . PRO   A 1 54  ? -50.29348 -18.75488 -5.66335  1.000 35.98585 ? 54  PRO   A CD  1 
ATOM   413  N  N   . LEU   A 1 55  ? -47.71040 -21.36666 -4.75491  1.000 31.05459 ? 55  LEU   A N   1 
ATOM   414  C  CA  . LEU   A 1 55  ? -46.50699 -22.15762 -4.50918  1.000 33.27043 ? 55  LEU   A CA  1 
ATOM   415  C  C   . LEU   A 1 55  ? -46.40597 -22.55616 -3.04300  1.000 32.88195 ? 55  LEU   A C   1 
ATOM   416  O  O   . LEU   A 1 55  ? -45.98909 -23.67354 -2.71903  1.000 30.68949 ? 55  LEU   A O   1 
ATOM   417  C  CB  . LEU   A 1 55  ? -45.26404 -21.37267 -4.93162  1.000 31.51066 ? 55  LEU   A CB  1 
ATOM   418  C  CG  . LEU   A 1 55  ? -43.90599 -22.02210 -4.64091  1.000 35.41207 ? 55  LEU   A CG  1 
ATOM   419  C  CD1 . LEU   A 1 55  ? -43.72594 -23.28001 -5.46483  1.000 36.22145 ? 55  LEU   A CD1 1 
ATOM   420  C  CD2 . LEU   A 1 55  ? -42.76627 -21.04330 -4.90131  1.000 33.59635 ? 55  LEU   A CD2 1 
ATOM   421  N  N   . HIS   A 1 56  ? -46.79905 -21.65680 -2.14041  1.000 30.53258 ? 56  HIS   A N   1 
ATOM   422  C  CA  . HIS   A 1 56  ? -46.72259 -21.96602 -0.71490  1.000 30.67098 ? 56  HIS   A CA  1 
ATOM   423  C  C   . HIS   A 1 56  ? -47.60996 -23.15568 -0.35585  1.000 31.40368 ? 56  HIS   A C   1 
ATOM   424  O  O   . HIS   A 1 56  ? -47.20223 -24.02772 0.41847   1.000 33.31951 ? 56  HIS   A O   1 
ATOM   425  C  CB  . HIS   A 1 56  ? -47.10470 -20.73580 0.11077   1.000 32.34698 ? 56  HIS   A CB  1 
ATOM   426  C  CG  . HIS   A 1 56  ? -46.17141 -19.57175 -0.06043  1.000 31.73029 ? 56  HIS   A CG  1 
ATOM   427  N  ND1 . HIS   A 1 56  ? -46.31378 -18.39479 0.64324   1.000 33.25534 ? 56  HIS   A ND1 1 
ATOM   428  C  CD2 . HIS   A 1 56  ? -45.08658 -19.40319 -0.85381  1.000 34.45643 ? 56  HIS   A CD2 1 
ATOM   429  C  CE1 . HIS   A 1 56  ? -45.35739 -17.55270 0.29366   1.000 33.45726 ? 56  HIS   A CE1 1 
ATOM   430  N  NE2 . HIS   A 1 56  ? -44.60124 -18.13789 -0.61709  1.000 33.86006 ? 56  HIS   A NE2 1 
ATOM   431  N  N   . GLN   A 1 57  ? -48.82273 -23.21864 -0.91542  1.000 31.14972 ? 57  GLN   A N   1 
ATOM   432  C  CA  . GLN   A 1 57  ? -49.71793 -24.33402 -0.60457  1.000 35.62908 ? 57  GLN   A CA  1 
ATOM   433  C  C   . GLN   A 1 57  ? -49.24949 -25.62246 -1.25933  1.000 33.14738 ? 57  GLN   A C   1 
ATOM   434  O  O   . GLN   A 1 57  ? -49.38982 -26.70521 -0.67931  1.000 34.40625 ? 57  GLN   A O   1 
ATOM   435  C  CB  . GLN   A 1 57  ? -51.14494 -24.01550 -1.04419  1.000 37.25742 ? 57  GLN   A CB  1 
ATOM   436  C  CG  . GLN   A 1 57  ? -51.57416 -22.63294 -0.65501  1.000 45.51836 ? 57  GLN   A CG  1 
ATOM   437  C  CD  . GLN   A 1 57  ? -51.68565 -22.49224 0.84348   1.000 59.44852 ? 57  GLN   A CD  1 
ATOM   438  O  OE1 . GLN   A 1 57  ? -51.02358 -21.65001 1.45527   1.000 58.32896 ? 57  GLN   A OE1 1 
ATOM   439  N  NE2 . GLN   A 1 57  ? -52.51667 -23.32992 1.45034   1.000 67.51479 ? 57  GLN   A NE2 1 
ATOM   440  N  N   . GLN   A 1 58  ? -48.72215 -25.52802 -2.48109  1.000 33.38542 ? 58  GLN   A N   1 
ATOM   441  C  CA  . GLN   A 1 58  ? -48.17981 -26.70570 -3.14857  1.000 34.22192 ? 58  GLN   A CA  1 
ATOM   442  C  C   . GLN   A 1 58  ? -47.01698 -27.29377 -2.36177  1.000 33.75258 ? 58  GLN   A C   1 
ATOM   443  O  O   . GLN   A 1 58  ? -46.91972 -28.51602 -2.20146  1.000 33.55400 ? 58  GLN   A O   1 
ATOM   444  C  CB  . GLN   A 1 58  ? -47.74784 -26.33859 -4.56825  1.000 37.90305 ? 58  GLN   A CB  1 
ATOM   445  C  CG  . GLN   A 1 58  ? -48.91835 -25.90402 -5.45134  1.000 42.31362 ? 58  GLN   A CG  1 
ATOM   446  C  CD  . GLN   A 1 58  ? -48.48330 -25.18976 -6.72141  1.000 45.72826 ? 58  GLN   A CD  1 
ATOM   447  O  OE1 . GLN   A 1 58  ? -47.30168 -24.90598 -6.91599  1.000 52.56288 ? 58  GLN   A OE1 1 
ATOM   448  N  NE2 . GLN   A 1 58  ? -49.44603 -24.89343 -7.59355  1.000 45.92408 ? 58  GLN   A NE2 1 
ATOM   449  N  N   . ILE   A 1 59  ? -46.12481 -26.43975 -1.85943  1.000 31.19742 ? 59  ILE   A N   1 
ATOM   450  C  CA  . ILE   A 1 59  ? -44.99695 -26.93526 -1.07651  1.000 31.33939 ? 59  ILE   A CA  1 
ATOM   451  C  C   . ILE   A 1 59  ? -45.47584 -27.49147 0.26404   1.000 32.59141 ? 59  ILE   A C   1 
ATOM   452  O  O   . ILE   A 1 59  ? -45.00622 -28.54073 0.71671   1.000 30.22239 ? 59  ILE   A O   1 
ATOM   453  C  CB  . ILE   A 1 59  ? -43.94833 -25.82274 -0.89401  1.000 33.45931 ? 59  ILE   A CB  1 
ATOM   454  C  CG1 . ILE   A 1 59  ? -43.27679 -25.50696 -2.23396  1.000 32.76330 ? 59  ILE   A CG1 1 
ATOM   455  C  CG2 . ILE   A 1 59  ? -42.88727 -26.25121 0.12596   1.000 31.43222 ? 59  ILE   A CG2 1 
ATOM   456  C  CD1 . ILE   A 1 59  ? -42.73285 -26.75800 -2.96137  1.000 31.19803 ? 59  ILE   A CD1 1 
ATOM   457  N  N   . ALA   A 1 60  ? -46.41231 -26.79966 0.92307   1.000 30.48049 ? 60  ALA   A N   1 
ATOM   458  C  CA  . ALA   A 1 60  ? -46.92479 -27.28817 2.20150   1.000 32.26585 ? 60  ALA   A CA  1 
ATOM   459  C  C   . ALA   A 1 60  ? -47.57305 -28.65990 2.04882   1.000 33.58385 ? 60  ALA   A C   1 
ATOM   460  O  O   . ALA   A 1 60  ? -47.35472 -29.55200 2.87566   1.000 31.97106 ? 60  ALA   A O   1 
ATOM   461  C  CB  . ALA   A 1 60  ? -47.92173 -26.28678 2.79237   1.000 29.57062 ? 60  ALA   A CB  1 
ATOM   462  N  N   . SER   A 1 61  ? -48.36652 -28.84971 0.99089   1.000 32.23380 ? 61  SER   A N   1 
ATOM   463  C  CA  . SER   A 1 61  ? -49.00475 -30.14517 0.76794   1.000 36.03082 ? 61  SER   A CA  1 
ATOM   464  C  C   . SER   A 1 61  ? -47.97610 -31.23078 0.48481   1.000 34.12105 ? 61  SER   A C   1 
ATOM   465  O  O   . SER   A 1 61  ? -48.14732 -32.38346 0.89907   1.000 35.13304 ? 61  SER   A O   1 
ATOM   466  C  CB  . SER   A 1 61  ? -50.00182 -30.05008 -0.38795  1.000 37.91243 ? 61  SER   A CB  1 
ATOM   467  O  OG  . SER   A 1 61  ? -51.10443 -29.23352 -0.03821  1.000 54.75202 ? 61  SER   A OG  1 
ATOM   468  N  N   . ALA   A 1 62  ? -46.90486 -30.88823 -0.23007  1.000 36.73254 ? 62  ALA   A N   1 
ATOM   469  C  CA  . ALA   A 1 62  ? -45.89898 -31.89387 -0.56008  1.000 37.13718 ? 62  ALA   A CA  1 
ATOM   470  C  C   . ALA   A 1 62  ? -45.10957 -32.30565 0.67347   1.000 34.47715 ? 62  ALA   A C   1 
ATOM   471  O  O   . ALA   A 1 62  ? -44.81355 -33.49378 0.86591   1.000 31.78834 ? 62  ALA   A O   1 
ATOM   472  C  CB  . ALA   A 1 62  ? -44.96277 -31.36160 -1.63944  1.000 34.17630 ? 62  ALA   A CB  1 
ATOM   473  N  N   . ILE   A 1 63  ? -44.74438 -31.33326 1.51074   1.000 32.11458 ? 63  ILE   A N   1 
ATOM   474  C  CA  . ILE   A 1 63  ? -44.07562 -31.65748 2.76617   1.000 34.64379 ? 63  ILE   A CA  1 
ATOM   475  C  C   . ILE   A 1 63  ? -45.01194 -32.43704 3.67935   1.000 32.59709 ? 63  ILE   A C   1 
ATOM   476  O  O   . ILE   A 1 63  ? -44.60215 -33.40466 4.33404   1.000 32.30184 ? 63  ILE   A O   1 
ATOM   477  C  CB  . ILE   A 1 63  ? -43.55566 -30.37458 3.43932   1.000 33.02961 ? 63  ILE   A CB  1 
ATOM   478  C  CG1 . ILE   A 1 63  ? -42.46251 -29.72888 2.57427   1.000 30.47254 ? 63  ILE   A CG1 1 
ATOM   479  C  CG2 . ILE   A 1 63  ? -43.03760 -30.68025 4.84095   1.000 31.54878 ? 63  ILE   A CG2 1 
ATOM   480  C  CD1 . ILE   A 1 63  ? -41.97630 -28.38078 3.10754   1.000 31.64051 ? 63  ILE   A CD1 1 
ATOM   481  N  N   . LYS   A 1 64  ? -46.28443 -32.03339 3.73510   1.000 30.73027 ? 64  LYS   A N   1 
ATOM   482  C  CA  . LYS   A 1 64  ? -47.23980 -32.72550 4.59518   1.000 34.74145 ? 64  LYS   A CA  1 
ATOM   483  C  C   . LYS   A 1 64  ? -47.38290 -34.19105 4.20773   1.000 34.73599 ? 64  LYS   A C   1 
ATOM   484  O  O   . LYS   A 1 64  ? -47.58259 -35.04415 5.07974   1.000 32.35297 ? 64  LYS   A O   1 
ATOM   485  C  CB  . LYS   A 1 64  ? -48.59398 -32.00999 4.55244   1.000 33.65717 ? 64  LYS   A CB  1 
ATOM   486  C  CG  . LYS   A 1 64  ? -49.66130 -32.58912 5.48462   1.000 39.78161 ? 64  LYS   A CG  1 
ATOM   487  C  CD  . LYS   A 1 64  ? -49.31128 -32.37032 6.95494   1.000 40.13090 ? 64  LYS   A CD  1 
ATOM   488  C  CE  . LYS   A 1 64  ? -50.54836 -32.47046 7.83476   1.000 46.73299 ? 64  LYS   A CE  1 
ATOM   489  N  NZ  . LYS   A 1 64  ? -51.04280 -33.86894 7.94332   1.000 47.45080 ? 64  LYS   A NZ  1 
ATOM   490  N  N   . ALA   A 1 65  ? -47.27068 -34.50381 2.91128   1.000 31.24269 ? 65  ALA   A N   1 
ATOM   491  C  CA  . ALA   A 1 65  ? -47.33344 -35.89646 2.47938   1.000 37.24640 ? 65  ALA   A CA  1 
ATOM   492  C  C   . ALA   A 1 65  ? -46.15109 -36.70058 3.00504   1.000 36.83189 ? 65  ALA   A C   1 
ATOM   493  O  O   . ALA   A 1 65  ? -46.29635 -37.89403 3.29672   1.000 33.71884 ? 65  ALA   A O   1 
ATOM   494  C  CB  . ALA   A 1 65  ? -47.39148 -35.97186 0.94946   1.000 38.72820 ? 65  ALA   A CB  1 
ATOM   495  N  N   . VAL   A 1 66  ? -44.97913 -36.07053 3.12814   1.000 33.02148 ? 66  VAL   A N   1 
ATOM   496  C  CA  . VAL   A 1 66  ? -43.82797 -36.74748 3.71945   1.000 31.66729 ? 66  VAL   A CA  1 
ATOM   497  C  C   . VAL   A 1 66  ? -44.05624 -36.96641 5.20910   1.000 35.36963 ? 66  VAL   A C   1 
ATOM   498  O  O   . VAL   A 1 66  ? -43.76714 -38.04497 5.74791   1.000 32.85276 ? 66  VAL   A O   1 
ATOM   499  C  CB  . VAL   A 1 66  ? -42.53932 -35.94004 3.46011   1.000 35.91485 ? 66  VAL   A CB  1 
ATOM   500  C  CG1 . VAL   A 1 66  ? -41.38006 -36.54489 4.22959   1.000 33.15593 ? 66  VAL   A CG1 1 
ATOM   501  C  CG2 . VAL   A 1 66  ? -42.22350 -35.89761 1.96789   1.000 34.11538 ? 66  VAL   A CG2 1 
ATOM   502  N  N   . VAL   A 1 67  ? -44.58940 -35.94795 5.89185   1.000 33.18872 ? 67  VAL   A N   1 
ATOM   503  C  CA  . VAL   A 1 67  ? -44.87496 -36.04567 7.32077   1.000 33.92254 ? 67  VAL   A CA  1 
ATOM   504  C  C   . VAL   A 1 67  ? -45.89210 -37.15035 7.58775   1.000 36.29478 ? 67  VAL   A C   1 
ATOM   505  O  O   . VAL   A 1 67  ? -45.73781 -37.94790 8.52367   1.000 34.61382 ? 67  VAL   A O   1 
ATOM   506  C  CB  . VAL   A 1 67  ? -45.36706 -34.68257 7.84471   1.000 35.63223 ? 67  VAL   A CB  1 
ATOM   507  C  CG1 . VAL   A 1 67  ? -45.93016 -34.80792 9.26101   1.000 34.03154 ? 67  VAL   A CG1 1 
ATOM   508  C  CG2 . VAL   A 1 67  ? -44.25584 -33.63043 7.76550   1.000 31.47534 ? 67  VAL   A CG2 1 
ATOM   509  N  N   . ASP   A 1 68  ? -46.94769 -37.21429 6.76961   1.000 32.65793 ? 68  ASP   A N   1 
ATOM   510  C  CA  . ASP   A 1 68  ? -47.97499 -38.23805 6.93381   1.000 34.09435 ? 68  ASP   A CA  1 
ATOM   511  C  C   . ASP   A 1 68  ? -47.44437 -39.63223 6.64035   1.000 38.12079 ? 68  ASP   A C   1 
ATOM   512  O  O   . ASP   A 1 68  ? -48.02935 -40.61646 7.10602   1.000 40.53783 ? 68  ASP   A O   1 
ATOM   513  C  CB  . ASP   A 1 68  ? -49.17329 -37.94953 6.02324   1.000 34.72797 ? 68  ASP   A CB  1 
ATOM   514  C  CG  . ASP   A 1 68  ? -49.94195 -36.70043 6.43226   1.000 42.41048 ? 68  ASP   A CG  1 
ATOM   515  O  OD1 . ASP   A 1 68  ? -49.82240 -36.26403 7.59947   1.000 40.47262 ? 68  ASP   A OD1 1 
ATOM   516  O  OD2 . ASP   A 1 68  ? -50.69055 -36.16922 5.58302   1.000 39.79420 ? 68  ASP   A OD2 1 
ATOM   517  N  N   . ALA   A 1 69  ? -46.36315 -39.73813 5.86718   1.000 36.78506 ? 69  ALA   A N   1 
ATOM   518  C  CA  . ALA   A 1 69  ? -45.71637 -41.01751 5.62429   1.000 39.09662 ? 69  ALA   A CA  1 
ATOM   519  C  C   . ALA   A 1 69  ? -44.82730 -41.45147 6.78091   1.000 37.99027 ? 69  ALA   A C   1 
ATOM   520  O  O   . ALA   A 1 69  ? -44.14610 -42.47324 6.66351   1.000 41.59140 ? 69  ALA   A O   1 
ATOM   521  C  CB  . ALA   A 1 69  ? -44.89610 -40.95802 4.33209   1.000 37.79071 ? 69  ALA   A CB  1 
ATOM   522  N  N   . GLY   A 1 70  ? -44.80543 -40.70147 7.87985   1.000 36.61316 ? 70  GLY   A N   1 
ATOM   523  C  CA  . GLY   A 1 70  ? -44.04781 -41.07809 9.05426   1.000 36.37519 ? 70  GLY   A CA  1 
ATOM   524  C  C   . GLY   A 1 70  ? -42.66825 -40.47019 9.18757   1.000 36.41169 ? 70  GLY   A C   1 
ATOM   525  O  O   . GLY   A 1 70  ? -41.92151 -40.88234 10.08155  1.000 36.33801 ? 70  GLY   A O   1 
ATOM   526  N  N   . VAL   A 1 71  ? -42.31164 -39.49863 8.35282   1.000 34.45435 ? 71  VAL   A N   1 
ATOM   527  C  CA  . VAL   A 1 71  ? -41.00064 -38.85944 8.39221   1.000 31.92685 ? 71  VAL   A CA  1 
ATOM   528  C  C   . VAL   A 1 71  ? -41.17108 -37.47478 9.01826   1.000 32.06982 ? 71  VAL   A C   1 
ATOM   529  O  O   . VAL   A 1 71  ? -41.71956 -36.56908 8.37537   1.000 30.47519 ? 71  VAL   A O   1 
ATOM   530  C  CB  . VAL   A 1 71  ? -40.37268 -38.76097 6.99550   1.000 34.83245 ? 71  VAL   A CB  1 
ATOM   531  C  CG1 . VAL   A 1 71  ? -39.00484 -38.05071 7.06927   1.000 33.29505 ? 71  VAL   A CG1 1 
ATOM   532  C  CG2 . VAL   A 1 71  ? -40.23703 -40.14673 6.36957   1.000 37.20908 ? 71  VAL   A CG2 1 
ATOM   533  N  N   . PRO   A 1 72  ? -40.71331 -37.25808 10.24853  1.000 31.92982 ? 72  PRO   A N   1 
ATOM   534  C  CA  . PRO   A 1 72  ? -40.81877 -35.91823 10.84077  1.000 35.18302 ? 72  PRO   A CA  1 
ATOM   535  C  C   . PRO   A 1 72  ? -39.93795 -34.92011 10.10014  1.000 34.53009 ? 72  PRO   A C   1 
ATOM   536  O  O   . PRO   A 1 72  ? -38.79138 -35.21511 9.74348   1.000 30.59444 ? 72  PRO   A O   1 
ATOM   537  C  CB  . PRO   A 1 72  ? -40.33992 -36.12325 12.28331  1.000 36.55027 ? 72  PRO   A CB  1 
ATOM   538  C  CG  . PRO   A 1 72  ? -39.46311 -37.35484 12.22617  1.000 34.03150 ? 72  PRO   A CG  1 
ATOM   539  C  CD  . PRO   A 1 72  ? -40.03809 -38.22400 11.13816  1.000 33.32909 ? 72  PRO   A CD  1 
ATOM   540  N  N   . CYS   A 1 73  ? -40.48845 -33.72671 9.87755   1.000 29.07892 ? 73  CYS   A N   1 
ATOM   541  C  CA  . CYS   A 1 73  ? -39.82561 -32.67668 9.11812   1.000 30.20009 ? 73  CYS   A CA  1 
ATOM   542  C  C   . CYS   A 1 73  ? -39.63596 -31.45113 10.00219  1.000 33.93159 ? 73  CYS   A C   1 
ATOM   543  O  O   . CYS   A 1 73  ? -40.55211 -31.05275 10.72784  1.000 32.04696 ? 73  CYS   A O   1 
ATOM   544  C  CB  . CYS   A 1 73  ? -40.63933 -32.30978 7.87590   1.000 30.29329 ? 73  CYS   A CB  1 
ATOM   545  S  SG  . CYS   A 1 73  ? -40.64135 -33.59217 6.60015   1.000 33.95495 ? 73  CYS   A SG  1 
ATOM   546  N  N   . TYR   A 1 74  ? -38.44769 -30.84762 9.93028   1.000 30.87095 ? 74  TYR   A N   1 
ATOM   547  C  CA  . TYR   A 1 74  ? -38.08103 -29.74493 10.80617  1.000 34.01734 ? 74  TYR   A CA  1 
ATOM   548  C  C   . TYR   A 1 74  ? -37.55960 -28.56662 9.99402   1.000 32.96636 ? 74  TYR   A C   1 
ATOM   549  O  O   . TYR   A 1 74  ? -36.97854 -28.74009 8.91888   1.000 31.77139 ? 74  TYR   A O   1 
ATOM   550  C  CB  . TYR   A 1 74  ? -37.01252 -30.17697 11.82538  1.000 32.77477 ? 74  TYR   A CB  1 
ATOM   551  C  CG  . TYR   A 1 74  ? -37.40447 -31.36952 12.67104  1.000 33.00460 ? 74  TYR   A CG  1 
ATOM   552  C  CD1 . TYR   A 1 74  ? -37.13676 -32.66311 12.23600  1.000 31.89492 ? 74  TYR   A CD1 1 
ATOM   553  C  CD2 . TYR   A 1 74  ? -38.01738 -31.20230 13.90855  1.000 32.54332 ? 74  TYR   A CD2 1 
ATOM   554  C  CE1 . TYR   A 1 74  ? -37.47966 -33.76126 12.99578  1.000 34.44937 ? 74  TYR   A CE1 1 
ATOM   555  C  CE2 . TYR   A 1 74  ? -38.36919 -32.30446 14.68338  1.000 35.36500 ? 74  TYR   A CE2 1 
ATOM   556  C  CZ  . TYR   A 1 74  ? -38.09501 -33.57982 14.21577  1.000 34.81401 ? 74  TYR   A CZ  1 
ATOM   557  O  OH  . TYR   A 1 74  ? -38.42600 -34.68714 14.95807  1.000 37.36251 ? 74  TYR   A OH  1 
ATOM   558  N  N   . PHE   A 1 75  ? -37.72807 -27.36392 10.54334  1.000 31.74446 ? 75  PHE   A N   1 
ATOM   559  C  CA  . PHE   A 1 75  ? -37.36910 -26.14508 9.83010   1.000 31.12495 ? 75  PHE   A CA  1 
ATOM   560  C  C   . PHE   A 1 75  ? -36.63680 -25.17935 10.75283  1.000 32.55813 ? 75  PHE   A C   1 
ATOM   561  O  O   . PHE   A 1 75  ? -37.11289 -24.87541 11.85126  1.000 32.67755 ? 75  PHE   A O   1 
ATOM   562  C  CB  . PHE   A 1 75  ? -38.62089 -25.47169 9.24418   1.000 31.13739 ? 75  PHE   A CB  1 
ATOM   563  C  CG  . PHE   A 1 75  ? -38.32424 -24.25994 8.39800   1.000 33.11420 ? 75  PHE   A CG  1 
ATOM   564  C  CD1 . PHE   A 1 75  ? -37.83281 -24.39999 7.10707   1.000 34.02097 ? 75  PHE   A CD1 1 
ATOM   565  C  CD2 . PHE   A 1 75  ? -38.53293 -22.98409 8.89439   1.000 32.32683 ? 75  PHE   A CD2 1 
ATOM   566  C  CE1 . PHE   A 1 75  ? -37.56262 -23.28351 6.32748   1.000 33.32152 ? 75  PHE   A CE1 1 
ATOM   567  C  CE2 . PHE   A 1 75  ? -38.26871 -21.86504 8.11880   1.000 31.86098 ? 75  PHE   A CE2 1 
ATOM   568  C  CZ  . PHE   A 1 75  ? -37.78642 -22.01581 6.83338   1.000 30.41830 ? 75  PHE   A CZ  1 
ATOM   569  N  N   . ILE   A 1 76  ? -35.47273 -24.71578 10.30710  1.000 29.92880 ? 76  ILE   A N   1 
ATOM   570  C  CA  . ILE   A 1 76  ? -34.77569 -23.57892 10.89761  1.000 32.12306 ? 76  ILE   A CA  1 
ATOM   571  C  C   . ILE   A 1 76  ? -34.82327 -22.45599 9.87411   1.000 34.33971 ? 76  ILE   A C   1 
ATOM   572  O  O   . ILE   A 1 76  ? -34.56780 -22.69136 8.68863   1.000 33.03524 ? 76  ILE   A O   1 
ATOM   573  C  CB  . ILE   A 1 76  ? -33.32063 -23.92882 11.26579  1.000 32.72678 ? 76  ILE   A CB  1 
ATOM   574  C  CG1 . ILE   A 1 76  ? -33.27881 -24.88315 12.46700  1.000 31.29812 ? 76  ILE   A CG1 1 
ATOM   575  C  CG2 . ILE   A 1 76  ? -32.51797 -22.65915 11.55500  1.000 32.92115 ? 76  ILE   A CG2 1 
ATOM   576  C  CD1 . ILE   A 1 76  ? -31.87182 -25.16239 12.97931  1.000 32.24134 ? 76  ILE   A CD1 1 
ATOM   577  N  N   . HIS   A 1 77  ? -35.15963 -21.24776 10.31988  1.000 32.66072 ? 77  HIS   A N   1 
ATOM   578  C  CA  . HIS   A 1 77  ? -35.31919 -20.12425 9.40216   1.000 34.13428 ? 77  HIS   A CA  1 
ATOM   579  C  C   . HIS   A 1 77  ? -33.99297 -19.70693 8.76760   1.000 33.43423 ? 77  HIS   A C   1 
ATOM   580  O  O   . HIS   A 1 77  ? -32.92500 -19.80010 9.37723   1.000 34.30810 ? 77  HIS   A O   1 
ATOM   581  C  CB  . HIS   A 1 77  ? -35.91627 -18.92132 10.13322  1.000 32.77859 ? 77  HIS   A CB  1 
ATOM   582  C  CG  . HIS   A 1 77  ? -37.28773 -19.16153 10.67462  1.000 36.85697 ? 77  HIS   A CG  1 
ATOM   583  N  ND1 . HIS   A 1 77  ? -37.50824 -19.72141 11.91491  1.000 38.10280 ? 77  HIS   A ND1 1 
ATOM   584  C  CD2 . HIS   A 1 77  ? -38.51136 -18.91947 10.14516  1.000 34.58999 ? 77  HIS   A CD2 1 
ATOM   585  C  CE1 . HIS   A 1 77  ? -38.80997 -19.81067 12.12820  1.000 40.18487 ? 77  HIS   A CE1 1 
ATOM   586  N  NE2 . HIS   A 1 77  ? -39.44121 -19.32783 11.07126  1.000 36.81190 ? 77  HIS   A NE2 1 
ATOM   587  N  N   . GLY   A 1 78  ? -34.07478 -19.22118 7.52671   1.000 32.82021 ? 78  GLY   A N   1 
ATOM   588  C  CA  . GLY   A 1 78  ? -32.94499 -18.61565 6.85972   1.000 33.84313 ? 78  GLY   A CA  1 
ATOM   589  C  C   . GLY   A 1 78  ? -33.06272 -17.09652 6.83860   1.000 35.01723 ? 78  GLY   A C   1 
ATOM   590  O  O   . GLY   A 1 78  ? -33.98396 -16.50404 7.38771   1.000 35.60064 ? 78  GLY   A O   1 
ATOM   591  N  N   . ASN   A 1 79  ? -32.09395 -16.46248 6.17894   1.000 37.42273 ? 79  ASN   A N   1 
ATOM   592  C  CA  . ASN   A 1 79  ? -32.13462 -15.00767 6.06873   1.000 39.51602 ? 79  ASN   A CA  1 
ATOM   593  C  C   . ASN   A 1 79  ? -33.26821 -14.53071 5.16861   1.000 38.37294 ? 79  ASN   A C   1 
ATOM   594  O  O   . ASN   A 1 79  ? -33.73864 -13.39913 5.33151   1.000 37.40426 ? 79  ASN   A O   1 
ATOM   595  C  CB  . ASN   A 1 79  ? -30.79299 -14.47764 5.55963   1.000 40.62064 ? 79  ASN   A CB  1 
ATOM   596  C  CG  . ASN   A 1 79  ? -30.42490 -15.02568 4.19919   1.000 40.92023 ? 79  ASN   A CG  1 
ATOM   597  O  OD1 . ASN   A 1 79  ? -30.21969 -16.22091 4.04744   1.000 41.19832 ? 79  ASN   A OD1 1 
ATOM   598  N  ND2 . ASN   A 1 79  ? -30.31732 -14.15002 3.20906   1.000 38.81077 ? 79  ASN   A ND2 1 
ATOM   599  N  N   . ARG   A 1 80  ? -33.72701 -15.36934 4.23760   1.000 35.32020 ? 80  ARG   A N   1 
ATOM   600  C  CA  . ARG   A 1 80  ? -34.79038 -14.97346 3.32290   1.000 38.42202 ? 80  ARG   A CA  1 
ATOM   601  C  C   . ARG   A 1 80  ? -36.17777 -15.22489 3.90083   1.000 35.15232 ? 80  ARG   A C   1 
ATOM   602  O  O   . ARG   A 1 80  ? -37.07697 -14.40099 3.71435   1.000 35.79924 ? 80  ARG   A O   1 
ATOM   603  C  CB  . ARG   A 1 80  ? -34.66192 -15.71615 1.98632   1.000 34.33190 ? 80  ARG   A CB  1 
ATOM   604  C  CG  . ARG   A 1 80  ? -33.29998 -15.61741 1.30586   1.000 36.33405 ? 80  ARG   A CG  1 
ATOM   605  C  CD  . ARG   A 1 80  ? -32.95584 -14.18732 0.91369   1.000 39.71322 ? 80  ARG   A CD  1 
ATOM   606  N  NE  . ARG   A 1 80  ? -33.88344 -13.65010 -0.07508  1.000 40.81298 ? 80  ARG   A NE  1 
ATOM   607  C  CZ  . ARG   A 1 80  ? -33.66352 -12.55774 -0.79600  1.000 47.62276 ? 80  ARG   A CZ  1 
ATOM   608  N  NH1 . ARG   A 1 80  ? -32.54340 -11.86296 -0.67538  1.000 39.58565 ? 80  ARG   A NH1 1 
ATOM   609  N  NH2 . ARG   A 1 80  ? -34.59175 -12.15174 -1.65959  1.000 42.53318 ? 80  ARG   A NH2 1 
ATOM   610  N  N   . ASP   A 1 81  ? -36.37715 -16.34377 4.59536   1.000 33.92363 ? 81  ASP   A N   1 
ATOM   611  C  CA  . ASP   A 1 81  ? -37.71245 -16.78100 4.99250   1.000 36.01319 ? 81  ASP   A CA  1 
ATOM   612  C  C   . ASP   A 1 81  ? -37.87325 -16.81656 6.51002   1.000 33.04774 ? 81  ASP   A C   1 
ATOM   613  O  O   . ASP   A 1 81  ? -38.52075 -17.70522 7.06354   1.000 33.61865 ? 81  ASP   A O   1 
ATOM   614  C  CB  . ASP   A 1 81  ? -38.05501 -18.14012 4.37617   1.000 30.44552 ? 81  ASP   A CB  1 
ATOM   615  C  CG  . ASP   A 1 81  ? -36.92291 -19.16886 4.49840   1.000 34.86953 ? 81  ASP   A CG  1 
ATOM   616  O  OD1 . ASP   A 1 81  ? -35.92048 -18.90961 5.20175   1.000 33.44886 ? 81  ASP   A OD1 1 
ATOM   617  O  OD2 . ASP   A 1 81  ? -37.06289 -20.26217 3.89837   1.000 32.42474 ? 81  ASP   A OD2 1 
ATOM   618  N  N   . PHE   A 1 82  ? -37.30768 -15.82573 7.20111   1.000 34.34652 ? 82  PHE   A N   1 
ATOM   619  C  CA  . PHE   A 1 82  ? -37.44170 -15.74622 8.65097   1.000 35.82679 ? 82  PHE   A CA  1 
ATOM   620  C  C   . PHE   A 1 82  ? -38.86792 -15.44746 9.10611   1.000 34.89848 ? 82  PHE   A C   1 
ATOM   621  O  O   . PHE   A 1 82  ? -39.14905 -15.55566 10.30284  1.000 34.98274 ? 82  PHE   A O   1 
ATOM   622  C  CB  . PHE   A 1 82  ? -36.48602 -14.68083 9.20923   1.000 36.67760 ? 82  PHE   A CB  1 
ATOM   623  C  CG  . PHE   A 1 82  ? -36.68405 -13.31219 8.61123   1.000 36.74525 ? 82  PHE   A CG  1 
ATOM   624  C  CD1 . PHE   A 1 82  ? -36.00623 -12.93534 7.45912   1.000 39.61946 ? 82  PHE   A CD1 1 
ATOM   625  C  CD2 . PHE   A 1 82  ? -37.53164 -12.39679 9.21134   1.000 35.65645 ? 82  PHE   A CD2 1 
ATOM   626  C  CE1 . PHE   A 1 82  ? -36.18637 -11.67897 6.90582   1.000 37.60697 ? 82  PHE   A CE1 1 
ATOM   627  C  CE2 . PHE   A 1 82  ? -37.71521 -11.13912 8.66485   1.000 36.31529 ? 82  PHE   A CE2 1 
ATOM   628  C  CZ  . PHE   A 1 82  ? -37.04535 -10.77980 7.50877   1.000 36.86993 ? 82  PHE   A CZ  1 
ATOM   629  N  N   . LEU   A 1 83  ? -39.77673 -15.07372 8.20829   1.000 31.22211 ? 83  LEU   A N   1 
ATOM   630  C  CA  . LEU   A 1 83  ? -41.15283 -14.84000 8.63391   1.000 31.30909 ? 83  LEU   A CA  1 
ATOM   631  C  C   . LEU   A 1 83  ? -42.02624 -16.09245 8.56867   1.000 34.45747 ? 83  LEU   A C   1 
ATOM   632  O  O   . LEU   A 1 83  ? -43.21211 -16.01397 8.89822   1.000 33.17067 ? 83  LEU   A O   1 
ATOM   633  C  CB  . LEU   A 1 83  ? -41.78780 -13.71507 7.80678   1.000 32.91799 ? 83  LEU   A CB  1 
ATOM   634  C  CG  . LEU   A 1 83  ? -41.30497 -12.28772 8.11604   1.000 35.63573 ? 83  LEU   A CG  1 
ATOM   635  C  CD1 . LEU   A 1 83  ? -42.05940 -11.27013 7.27206   1.000 33.52578 ? 83  LEU   A CD1 1 
ATOM   636  C  CD2 . LEU   A 1 83  ? -41.45411 -11.95607 9.60347   1.000 33.69928 ? 83  LEU   A CD2 1 
ATOM   637  N  N   . VAL   A 1 84  ? -41.47628 -17.24693 8.18049   1.000 31.60046 ? 84  VAL   A N   1 
ATOM   638  C  CA  . VAL   A 1 84  ? -42.26492 -18.47853 8.18399   1.000 29.99487 ? 84  VAL   A CA  1 
ATOM   639  C  C   . VAL   A 1 84  ? -42.77042 -18.75193 9.59387   1.000 37.86694 ? 84  VAL   A C   1 
ATOM   640  O  O   . VAL   A 1 84  ? -41.98755 -18.81428 10.55273  1.000 33.62761 ? 84  VAL   A O   1 
ATOM   641  C  CB  . VAL   A 1 84  ? -41.42942 -19.65529 7.65798   1.000 31.77980 ? 84  VAL   A CB  1 
ATOM   642  C  CG1 . VAL   A 1 84  ? -42.13858 -20.97437 7.93830   1.000 28.66643 ? 84  VAL   A CG1 1 
ATOM   643  C  CG2 . VAL   A 1 84  ? -41.16255 -19.50136 6.16886   1.000 29.81323 ? 84  VAL   A CG2 1 
ATOM   644  N  N   . GLY   A 1 85  ? -44.08649 -18.91841 9.73040   1.000 32.68852 ? 85  GLY   A N   1 
ATOM   645  C  CA  . GLY   A 1 85  ? -44.67282 -19.01115 11.05491  1.000 36.64714 ? 85  GLY   A CA  1 
ATOM   646  C  C   . GLY   A 1 85  ? -45.43510 -20.28917 11.34311  1.000 39.30565 ? 85  GLY   A C   1 
ATOM   647  O  O   . GLY   A 1 85  ? -45.36894 -21.25644 10.57744  1.000 32.90629 ? 85  GLY   A O   1 
ATOM   648  N  N   . GLN   A 1 86  ? -46.18322 -20.29142 12.45071  1.000 35.68863 ? 86  GLN   A N   1 
ATOM   649  C  CA  . GLN   A 1 86  ? -46.84077 -21.50435 12.91634  1.000 38.89340 ? 86  GLN   A CA  1 
ATOM   650  C  C   . GLN   A 1 86  ? -48.03337 -21.89745 12.05273  1.000 38.55654 ? 86  GLN   A C   1 
ATOM   651  O  O   . GLN   A 1 86  ? -48.39537 -23.07763 12.02620  1.000 38.68731 ? 86  GLN   A O   1 
ATOM   652  C  CB  . GLN   A 1 86  ? -47.27702 -21.33616 14.37622  1.000 41.82602 ? 86  GLN   A CB  1 
ATOM   653  C  CG  . GLN   A 1 86  ? -46.10649 -21.17944 15.34122  1.000 43.69982 ? 86  GLN   A CG  1 
ATOM   654  C  CD  . GLN   A 1 86  ? -45.32067 -22.47053 15.55820  1.000 53.75507 ? 86  GLN   A CD  1 
ATOM   655  O  OE1 . GLN   A 1 86  ? -45.62905 -23.51465 14.97882  1.000 53.46616 ? 86  GLN   A OE1 1 
ATOM   656  N  NE2 . GLN   A 1 86  ? -44.27985 -22.39225 16.38351  1.000 60.35844 ? 86  GLN   A NE2 1 
ATOM   657  N  N   . ARG   A 1 87  ? -48.65793 -20.94634 11.35585  1.000 34.19367 ? 87  ARG   A N   1 
ATOM   658  C  CA  . ARG   A 1 87  ? -49.69605 -21.31369 10.39820  1.000 39.88226 ? 87  ARG   A CA  1 
ATOM   659  C  C   . ARG   A 1 87  ? -49.12175 -22.18300 9.28544   1.000 39.26410 ? 87  ARG   A C   1 
ATOM   660  O  O   . ARG   A 1 87  ? -49.66812 -23.24486 8.96540   1.000 37.36521 ? 87  ARG   A O   1 
ATOM   661  C  CB  . ARG   A 1 87  ? -50.35301 -20.05988 9.81942   1.000 42.04141 ? 87  ARG   A CB  1 
ATOM   662  C  CG  . ARG   A 1 87  ? -51.55175 -20.33965 8.92149   1.000 40.97089 ? 87  ARG   A CG  1 
ATOM   663  C  CD  . ARG   A 1 87  ? -52.15307 -19.02842 8.41967   1.000 46.61146 ? 87  ARG   A CD  1 
ATOM   664  N  NE  . ARG   A 1 87  ? -53.19783 -19.24270 7.42974   1.000 53.68044 ? 87  ARG   A NE  1 
ATOM   665  C  CZ  . ARG   A 1 87  ? -53.97021 -18.28382 6.93712   1.000 58.35983 ? 87  ARG   A CZ  1 
ATOM   666  N  NH1 . ARG   A 1 87  ? -53.82005 -17.02080 7.30022   1.000 51.43060 ? 87  ARG   A NH1 1 
ATOM   667  N  NH2 . ARG   A 1 87  ? -54.91930 -18.60118 6.05948   1.000 63.84459 ? 87  ARG   A NH2 1 
ATOM   668  N  N   . PHE   A 1 88  ? -48.01427 -21.74805 8.68061   1.000 34.23396 ? 88  PHE   A N   1 
ATOM   669  C  CA  . PHE   A 1 88  ? -47.39455 -22.57837 7.65607   1.000 34.96183 ? 88  PHE   A CA  1 
ATOM   670  C  C   . PHE   A 1 88  ? -46.85433 -23.87557 8.24825   1.000 36.44895 ? 88  PHE   A C   1 
ATOM   671  O  O   . PHE   A 1 88  ? -46.91569 -24.92304 7.59547   1.000 32.47027 ? 88  PHE   A O   1 
ATOM   672  C  CB  . PHE   A 1 88  ? -46.28362 -21.81391 6.93173   1.000 35.32105 ? 88  PHE   A CB  1 
ATOM   673  C  CG  . PHE   A 1 88  ? -45.66267 -22.59559 5.80754   1.000 34.62330 ? 88  PHE   A CG  1 
ATOM   674  C  CD1 . PHE   A 1 88  ? -46.28499 -22.66263 4.57063   1.000 35.26459 ? 88  PHE   A CD1 1 
ATOM   675  C  CD2 . PHE   A 1 88  ? -44.48514 -23.29270 5.99771   1.000 32.46890 ? 88  PHE   A CD2 1 
ATOM   676  C  CE1 . PHE   A 1 88  ? -45.72849 -23.40381 3.53640   1.000 35.61444 ? 88  PHE   A CE1 1 
ATOM   677  C  CE2 . PHE   A 1 88  ? -43.91648 -24.03405 4.96301   1.000 35.35662 ? 88  PHE   A CE2 1 
ATOM   678  C  CZ  . PHE   A 1 88  ? -44.53832 -24.08747 3.73694   1.000 31.23608 ? 88  PHE   A CZ  1 
ATOM   679  N  N   . ALA   A 1 89  ? -46.34813 -23.83361 9.48561   1.000 36.20492 ? 89  ALA   A N   1 
ATOM   680  C  CA  . ALA   A 1 89  ? -45.89874 -25.06180 10.13688  1.000 37.51155 ? 89  ALA   A CA  1 
ATOM   681  C  C   . ALA   A 1 89  ? -47.03466 -26.07159 10.24115  1.000 36.92136 ? 89  ALA   A C   1 
ATOM   682  O  O   . ALA   A 1 89  ? -46.84312 -27.26434 9.96940   1.000 36.78202 ? 89  ALA   A O   1 
ATOM   683  C  CB  . ALA   A 1 89  ? -45.32729 -24.75425 11.52252  1.000 33.76360 ? 89  ALA   A CB  1 
ATOM   684  N  N   . ARG   A 1 90  ? -48.22808 -25.61046 10.62386  1.000 35.50782 ? 90  ARG   A N   1 
ATOM   685  C  CA  . ARG   A 1 90  ? -49.37153 -26.51240 10.73718  1.000 37.71505 ? 90  ARG   A CA  1 
ATOM   686  C  C   . ARG   A 1 90  ? -49.81758 -27.02106 9.37065   1.000 38.86141 ? 90  ARG   A C   1 
ATOM   687  O  O   . ARG   A 1 90  ? -50.14128 -28.20545 9.22391   1.000 42.12028 ? 90  ARG   A O   1 
ATOM   688  C  CB  . ARG   A 1 90  ? -50.52824 -25.81397 11.45739  1.000 43.28552 ? 90  ARG   A CB  1 
ATOM   689  C  CG  . ARG   A 1 90  ? -50.41945 -25.85394 12.97815  1.000 52.05873 ? 90  ARG   A CG  1 
ATOM   690  C  CD  . ARG   A 1 90  ? -51.54165 -25.08951 13.66592  1.000 64.93802 ? 90  ARG   A CD  1 
ATOM   691  N  NE  . ARG   A 1 90  ? -51.81735 -23.80648 13.02980  1.000 77.06230 ? 90  ARG   A NE  1 
ATOM   692  C  CZ  . ARG   A 1 90  ? -51.88624 -22.64938 13.67547  1.000 72.69344 ? 90  ARG   A CZ  1 
ATOM   693  N  NH1 . ARG   A 1 90  ? -51.66239 -22.56936 14.97737  1.000 68.19458 ? 90  ARG   A NH1 1 
ATOM   694  N  NH2 . ARG   A 1 90  ? -52.18423 -21.54414 12.99742  1.000 64.97430 ? 90  ARG   A NH2 1 
ATOM   695  N  N   . GLN   A 1 91  ? -49.84083 -26.14428 8.35971   1.000 36.45404 ? 91  GLN   A N   1 
ATOM   696  C  CA  . GLN   A 1 91  ? -50.23314 -26.56798 7.01546   1.000 40.34141 ? 91  GLN   A CA  1 
ATOM   697  C  C   . GLN   A 1 91  ? -49.29420 -27.63695 6.46954   1.000 38.87926 ? 91  GLN   A C   1 
ATOM   698  O  O   . GLN   A 1 91  ? -49.73715 -28.57597 5.79751   1.000 33.72951 ? 91  GLN   A O   1 
ATOM   699  C  CB  . GLN   A 1 91  ? -50.26160 -25.36948 6.06190   1.000 39.70544 ? 91  GLN   A CB  1 
ATOM   700  C  CG  . GLN   A 1 91  ? -51.41192 -24.40515 6.28434   1.000 49.85240 ? 91  GLN   A CG  1 
ATOM   701  C  CD  . GLN   A 1 91  ? -51.27608 -23.12223 5.46869   1.000 64.17552 ? 91  GLN   A CD  1 
ATOM   702  O  OE1 . GLN   A 1 91  ? -50.26098 -22.88974 4.81131   1.000 54.53477 ? 91  GLN   A OE1 1 
ATOM   703  N  NE2 . GLN   A 1 91  ? -52.30636 -22.28356 5.51212   1.000 68.89832 ? 91  GLN   A NE2 1 
ATOM   704  N  N   . SER   A 1 92  ? -47.99062 -27.50128 6.72987   1.000 33.62398 ? 92  SER   A N   1 
ATOM   705  C  CA  . SER   A 1 92  ? -46.99044 -28.40250 6.17609   1.000 32.11087 ? 92  SER   A CA  1 
ATOM   706  C  C   . SER   A 1 92  ? -46.68447 -29.59165 7.07449   1.000 32.85824 ? 92  SER   A C   1 
ATOM   707  O  O   . SER   A 1 92  ? -45.98915 -30.51413 6.63481   1.000 33.68501 ? 92  SER   A O   1 
ATOM   708  C  CB  . SER   A 1 92  ? -45.68278 -27.64382 5.91171   1.000 33.51068 ? 92  SER   A CB  1 
ATOM   709  O  OG  . SER   A 1 92  ? -45.17423 -27.10196 7.12129   1.000 32.45319 ? 92  SER   A OG  1 
ATOM   710  N  N   . GLY   A 1 93  ? -47.16580 -29.58978 8.31455   1.000 34.09061 ? 93  GLY   A N   1 
ATOM   711  C  CA  . GLY   A 1 93  ? -46.75020 -30.58799 9.27464   1.000 32.36514 ? 93  GLY   A CA  1 
ATOM   712  C  C   . GLY   A 1 93  ? -45.33119 -30.42962 9.77624   1.000 35.72854 ? 93  GLY   A C   1 
ATOM   713  O  O   . GLY   A 1 93  ? -44.83003 -31.32143 10.46832  1.000 35.26539 ? 93  GLY   A O   1 
ATOM   714  N  N   . MET   A 1 94  ? -44.66654 -29.32276 9.45687   1.000 32.92993 ? 94  MET   A N   1 
ATOM   715  C  CA  . MET   A 1 94  ? -43.29516 -29.11846 9.89491   1.000 31.84636 ? 94  MET   A CA  1 
ATOM   716  C  C   . MET   A 1 94  ? -43.25416 -28.59495 11.32258  1.000 39.46696 ? 94  MET   A C   1 
ATOM   717  O  O   . MET   A 1 94  ? -44.17325 -27.91236 11.78593  1.000 38.40666 ? 94  MET   A O   1 
ATOM   718  C  CB  . MET   A 1 94  ? -42.56640 -28.12332 8.99295   1.000 33.18242 ? 94  MET   A CB  1 
ATOM   719  C  CG  . MET   A 1 94  ? -41.86307 -28.75598 7.82733   1.000 39.57723 ? 94  MET   A CG  1 
ATOM   720  S  SD  . MET   A 1 94  ? -40.73005 -27.66922 6.93746   1.000 40.77286 ? 94  MET   A SD  1 
ATOM   721  C  CE  . MET   A 1 94  ? -41.54491 -26.08515 6.99847   1.000 34.65115 ? 94  MET   A CE  1 
ATOM   722  N  N   . ILE   A 1 95  ? -42.15288 -28.89364 12.00889  1.000 34.87038 ? 95  ILE   A N   1 
ATOM   723  C  CA  . ILE   A 1 95  ? -41.86754 -28.34574 13.32954  1.000 34.19621 ? 95  ILE   A CA  1 
ATOM   724  C  C   . ILE   A 1 95  ? -40.82258 -27.24928 13.17613  1.000 36.88530 ? 95  ILE   A C   1 
ATOM   725  O  O   . ILE   A 1 95  ? -39.77224 -27.46511 12.55823  1.000 34.74722 ? 95  ILE   A O   1 
ATOM   726  C  CB  . ILE   A 1 95  ? -41.38232 -29.44506 14.28895  1.000 33.97365 ? 95  ILE   A CB  1 
ATOM   727  C  CG1 . ILE   A 1 95  ? -42.51792 -30.44033 14.54552  1.000 41.89941 ? 95  ILE   A CG1 1 
ATOM   728  C  CG2 . ILE   A 1 95  ? -40.90067 -28.84806 15.59513  1.000 36.41777 ? 95  ILE   A CG2 1 
ATOM   729  C  CD1 . ILE   A 1 95  ? -42.07213 -31.72525 15.21246  1.000 40.34184 ? 95  ILE   A CD1 1 
ATOM   730  N  N   . LEU   A 1 96  ? -41.10665 -26.07523 13.73468  1.000 33.55369 ? 96  LEU   A N   1 
ATOM   731  C  CA  . LEU   A 1 96  ? -40.17921 -24.95317 13.69902  1.000 33.24731 ? 96  LEU   A CA  1 
ATOM   732  C  C   . LEU   A 1 96  ? -39.18261 -25.06454 14.84616  1.000 36.58538 ? 96  LEU   A C   1 
ATOM   733  O  O   . LEU   A 1 96  ? -39.57973 -25.18736 16.00872  1.000 34.60398 ? 96  LEU   A O   1 
ATOM   734  C  CB  . LEU   A 1 96  ? -40.93723 -23.62776 13.79182  1.000 36.83321 ? 96  LEU   A CB  1 
ATOM   735  C  CG  . LEU   A 1 96  ? -42.08564 -23.40401 12.80061  1.000 39.54287 ? 96  LEU   A CG  1 
ATOM   736  C  CD1 . LEU   A 1 96  ? -42.69695 -22.01806 13.00401  1.000 38.52020 ? 96  LEU   A CD1 1 
ATOM   737  C  CD2 . LEU   A 1 96  ? -41.59143 -23.57130 11.37220  1.000 34.82113 ? 96  LEU   A CD2 1 
ATOM   738  N  N   . LEU   A 1 97  ? -37.89509 -25.00151 14.52040  1.000 32.40010 ? 97  LEU   A N   1 
ATOM   739  C  CA  . LEU   A 1 97  ? -36.82588 -25.10133 15.50407  1.000 34.85874 ? 97  LEU   A CA  1 
ATOM   740  C  C   . LEU   A 1 97  ? -36.17324 -23.73993 15.73092  1.000 39.36198 ? 97  LEU   A C   1 
ATOM   741  O  O   . LEU   A 1 97  ? -36.40947 -22.77695 14.99536  1.000 37.77025 ? 97  LEU   A O   1 
ATOM   742  C  CB  . LEU   A 1 97  ? -35.78214 -26.13455 15.05668  1.000 31.85569 ? 97  LEU   A CB  1 
ATOM   743  C  CG  . LEU   A 1 97  ? -36.29718 -27.57129 14.91594  1.000 34.19023 ? 97  LEU   A CG  1 
ATOM   744  C  CD1 . LEU   A 1 97  ? -35.17383 -28.51490 14.50283  1.000 33.69641 ? 97  LEU   A CD1 1 
ATOM   745  C  CD2 . LEU   A 1 97  ? -36.90498 -28.02702 16.23298  1.000 34.97362 ? 97  LEU   A CD2 1 
ATOM   746  N  N   . ALA   A 1 98  ? -35.33642 -23.66812 16.76928  1.000 39.20990 ? 98  ALA   A N   1 
ATOM   747  C  CA  . ALA   A 1 98  ? -34.62623 -22.43909 17.09829  1.000 36.91157 ? 98  ALA   A CA  1 
ATOM   748  C  C   . ALA   A 1 98  ? -33.47474 -22.21516 16.11996  1.000 38.73681 ? 98  ALA   A C   1 
ATOM   749  O  O   . ALA   A 1 98  ? -33.12987 -23.08948 15.32195  1.000 36.09576 ? 98  ALA   A O   1 
ATOM   750  C  CB  . ALA   A 1 98  ? -34.11111 -22.48564 18.53797  1.000 39.81423 ? 98  ALA   A CB  1 
ATOM   751  N  N   . GLU   A 1 99  ? -32.86039 -21.02480 16.18527  1.000 39.29285 ? 99  GLU   A N   1 
ATOM   752  C  CA  . GLU   A 1 99  ? -31.81016 -20.71940 15.21441  1.000 41.21448 ? 99  GLU   A CA  1 
ATOM   753  C  C   . GLU   A 1 99  ? -30.56808 -21.57768 15.41312  1.000 37.76179 ? 99  GLU   A C   1 
ATOM   754  O  O   . GLU   A 1 99  ? -29.77909 -21.72221 14.47399  1.000 35.95827 ? 99  GLU   A O   1 
ATOM   755  C  CB  . GLU   A 1 99  ? -31.42845 -19.23453 15.24420  1.000 45.25219 ? 99  GLU   A CB  1 
ATOM   756  C  CG  . GLU   A 1 99  ? -30.82874 -18.72245 16.52341  1.000 46.70105 ? 99  GLU   A CG  1 
ATOM   757  C  CD  . GLU   A 1 99  ? -30.30710 -17.29753 16.37373  1.000 50.71491 ? 99  GLU   A CD  1 
ATOM   758  O  OE1 . GLU   A 1 99  ? -31.11635 -16.38523 16.09800  1.000 45.53203 ? 99  GLU   A OE1 1 
ATOM   759  O  OE2 . GLU   A 1 99  ? -29.08287 -17.09309 16.52569  1.000 48.58573 ? 99  GLU   A OE2 1 
ATOM   760  N  N   . GLU   A 1 100 ? -30.38510 -22.15215 16.60120  1.000 37.80985 ? 100 GLU   A N   1 
ATOM   761  C  CA  . GLU   A 1 100 ? -29.34135 -23.13489 16.86848  1.000 39.01442 ? 100 GLU   A CA  1 
ATOM   762  C  C   . GLU   A 1 100 ? -29.97899 -24.32561 17.56755  1.000 40.31788 ? 100 GLU   A C   1 
ATOM   763  O  O   . GLU   A 1 100 ? -30.73212 -24.14712 18.52952  1.000 39.05418 ? 100 GLU   A O   1 
ATOM   764  C  CB  . GLU   A 1 100 ? -28.22602 -22.54878 17.74709  1.000 42.68486 ? 100 GLU   A CB  1 
ATOM   765  C  CG  . GLU   A 1 100 ? -27.44369 -21.41740 17.10245  1.000 41.38278 ? 100 GLU   A CG  1 
ATOM   766  C  CD  . GLU   A 1 100 ? -26.37651 -20.82747 18.01333  1.000 45.94606 ? 100 GLU   A CD  1 
ATOM   767  O  OE1 . GLU   A 1 100 ? -26.22244 -21.29510 19.16518  1.000 45.16444 ? 100 GLU   A OE1 1 
ATOM   768  O  OE2 . GLU   A 1 100 ? -25.69102 -19.88473 17.56895  1.000 43.23494 ? 100 GLU   A OE2 1 
ATOM   769  N  N   . GLU   A 1 101 ? -29.68808 -25.53421 17.08788  1.000 35.02298 ? 101 GLU   A N   1 
ATOM   770  C  CA  . GLU   A 1 101 ? -30.17063 -26.74274 17.74083  1.000 38.66959 ? 101 GLU   A CA  1 
ATOM   771  C  C   . GLU   A 1 101 ? -29.05471 -27.77164 17.79265  1.000 40.92582 ? 101 GLU   A C   1 
ATOM   772  O  O   . GLU   A 1 101 ? -28.27753 -27.90423 16.84421  1.000 38.98602 ? 101 GLU   A O   1 
ATOM   773  C  CB  . GLU   A 1 101 ? -31.37868 -27.35470 17.01808  1.000 36.84183 ? 101 GLU   A CB  1 
ATOM   774  C  CG  . GLU   A 1 101 ? -32.60969 -26.47821 16.97075  1.000 40.41626 ? 101 GLU   A CG  1 
ATOM   775  C  CD  . GLU   A 1 101 ? -33.40700 -26.47249 18.26187  1.000 41.00076 ? 101 GLU   A CD  1 
ATOM   776  O  OE1 . GLU   A 1 101 ? -33.02399 -27.16419 19.23351  1.000 45.00311 ? 101 GLU   A OE1 1 
ATOM   777  O  OE2 . GLU   A 1 101 ? -34.42729 -25.75771 18.29762  1.000 38.58306 ? 101 GLU   A OE2 1 
ATOM   778  N  N   . ARG   A 1 102 ? -28.99417 -28.50861 18.89559  1.000 41.88960 ? 102 ARG   A N   1 
ATOM   779  C  CA  . ARG   A 1 102 ? -28.06389 -29.61970 19.06050  1.000 45.96177 ? 102 ARG   A CA  1 
ATOM   780  C  C   . ARG   A 1 102 ? -28.84364 -30.92379 18.95588  1.000 42.72025 ? 102 ARG   A C   1 
ATOM   781  O  O   . ARG   A 1 102 ? -29.79850 -31.13871 19.70940  1.000 47.55046 ? 102 ARG   A O   1 
ATOM   782  C  CB  . ARG   A 1 102 ? -27.34027 -29.52564 20.40391  1.000 47.95530 ? 102 ARG   A CB  1 
ATOM   783  C  CG  . ARG   A 1 102 ? -26.11601 -30.42153 20.53584  1.000 51.52297 ? 102 ARG   A CG  1 
ATOM   784  C  CD  . ARG   A 1 102 ? -25.54348 -30.33729 21.94483  1.000 58.35700 ? 102 ARG   A CD  1 
ATOM   785  N  NE  . ARG   A 1 102 ? -25.69234 -28.99232 22.48482  1.000 64.53821 ? 102 ARG   A NE  1 
ATOM   786  C  CZ  . ARG   A 1 102 ? -26.47840 -28.67342 23.50407  1.000 71.27127 ? 102 ARG   A CZ  1 
ATOM   787  N  NH1 . ARG   A 1 102 ? -27.17710 -29.59250 24.15160  1.000 74.29981 ? 102 ARG   A NH1 1 
ATOM   788  N  NH2 . ARG   A 1 102 ? -26.57202 -27.39878 23.87673  1.000 67.02281 ? 102 ARG   A NH2 1 
ATOM   789  N  N   . LEU   A 1 103 ? -28.44577 -31.78368 18.02271  1.000 43.04125 ? 103 LEU   A N   1 
ATOM   790  C  CA  . LEU   A 1 103 ? -29.11374 -33.05556 17.78835  1.000 43.59440 ? 103 LEU   A CA  1 
ATOM   791  C  C   . LEU   A 1 103 ? -28.20502 -34.21851 18.15439  1.000 43.12250 ? 103 LEU   A C   1 
ATOM   792  O  O   . LEU   A 1 103 ? -26.97776 -34.11732 18.08576  1.000 45.28082 ? 103 LEU   A O   1 
ATOM   793  C  CB  . LEU   A 1 103 ? -29.53051 -33.22270 16.32317  1.000 41.66876 ? 103 LEU   A CB  1 
ATOM   794  C  CG  . LEU   A 1 103 ? -30.19797 -32.07414 15.57759  1.000 41.25731 ? 103 LEU   A CG  1 
ATOM   795  C  CD1 . LEU   A 1 103 ? -30.33251 -32.43660 14.10735  1.000 39.18392 ? 103 LEU   A CD1 1 
ATOM   796  C  CD2 . LEU   A 1 103 ? -31.54654 -31.75632 16.19891  1.000 37.60349 ? 103 LEU   A CD2 1 
ATOM   797  N  N   . ASP   A 1 104 ? -28.82612 -35.33016 18.53021  1.000 38.71238 ? 104 ASP   A N   1 
ATOM   798  C  CA  . ASP   A 1 104 ? -28.14948 -36.61762 18.61012  1.000 50.46205 ? 104 ASP   A CA  1 
ATOM   799  C  C   . ASP   A 1 104 ? -28.49067 -37.38151 17.33870  1.000 45.70995 ? 104 ASP   A C   1 
ATOM   800  O  O   . ASP   A 1 104 ? -29.63793 -37.79081 17.14453  1.000 46.30202 ? 104 ASP   A O   1 
ATOM   801  C  CB  . ASP   A 1 104 ? -28.57331 -37.40346 19.84656  1.000 55.39567 ? 104 ASP   A CB  1 
ATOM   802  C  CG  . ASP   A 1 104 ? -28.10128 -38.84595 19.80309  1.000 58.67823 ? 104 ASP   A CG  1 
ATOM   803  O  OD1 . ASP   A 1 104 ? -26.87162 -39.06183 19.80884  1.000 57.45574 ? 104 ASP   A OD1 1 
ATOM   804  O  OD2 . ASP   A 1 104 ? -28.95680 -39.75957 19.75307  1.000 63.46925 ? 104 ASP   A OD2 1 
ATOM   805  N  N   . LEU   A 1 105 ? -27.50445 -37.55621 16.46833  1.000 44.48716 ? 105 LEU   A N   1 
ATOM   806  C  CA  . LEU   A 1 105 ? -27.67834 -38.29047 15.22026  1.000 43.98191 ? 105 LEU   A CA  1 
ATOM   807  C  C   . LEU   A 1 105 ? -26.87970 -39.58339 15.34047  1.000 46.23320 ? 105 LEU   A C   1 
ATOM   808  O  O   . LEU   A 1 105 ? -25.67215 -39.60615 15.10429  1.000 42.50078 ? 105 LEU   A O   1 
ATOM   809  C  CB  . LEU   A 1 105 ? -27.23047 -37.46037 14.02407  1.000 40.44516 ? 105 LEU   A CB  1 
ATOM   810  C  CG  . LEU   A 1 105 ? -27.94219 -36.11875 13.85791  1.000 42.33141 ? 105 LEU   A CG  1 
ATOM   811  C  CD1 . LEU   A 1 105 ? -27.32771 -35.33245 12.70606  1.000 39.90291 ? 105 LEU   A CD1 1 
ATOM   812  C  CD2 . LEU   A 1 105 ? -29.44699 -36.32860 13.65664  1.000 36.39091 ? 105 LEU   A CD2 1 
ATOM   813  N  N   . TYR   A 1 106 ? -27.56860 -40.65859 15.72092  1.000 42.41700 ? 106 TYR   A N   1 
ATOM   814  C  CA  . TYR   A 1 106 ? -26.97024 -41.99000 15.82210  1.000 43.49866 ? 106 TYR   A CA  1 
ATOM   815  C  C   . TYR   A 1 106 ? -25.71381 -41.98065 16.68846  1.000 47.86974 ? 106 TYR   A C   1 
ATOM   816  O  O   . TYR   A 1 106 ? -24.72192 -42.64801 16.39114  1.000 46.80822 ? 106 TYR   A O   1 
ATOM   817  C  CB  . TYR   A 1 106 ? -26.67746 -42.55879 14.43297  1.000 41.01715 ? 106 TYR   A CB  1 
ATOM   818  C  CG  . TYR   A 1 106 ? -27.78214 -42.26919 13.45128  1.000 42.21068 ? 106 TYR   A CG  1 
ATOM   819  C  CD1 . TYR   A 1 106 ? -28.98006 -42.97429 13.50084  1.000 42.44729 ? 106 TYR   A CD1 1 
ATOM   820  C  CD2 . TYR   A 1 106 ? -27.64350 -41.27469 12.49508  1.000 38.80965 ? 106 TYR   A CD2 1 
ATOM   821  C  CE1 . TYR   A 1 106 ? -30.01040 -42.69793 12.61603  1.000 40.85907 ? 106 TYR   A CE1 1 
ATOM   822  C  CE2 . TYR   A 1 106 ? -28.67350 -40.98679 11.60273  1.000 40.35497 ? 106 TYR   A CE2 1 
ATOM   823  C  CZ  . TYR   A 1 106 ? -29.85069 -41.70581 11.66612  1.000 38.78046 ? 106 TYR   A CZ  1 
ATOM   824  O  OH  . TYR   A 1 106 ? -30.86689 -41.42754 10.77807  1.000 40.23781 ? 106 TYR   A OH  1 
ATOM   825  N  N   . GLY   A 1 107 ? -25.74905 -41.20060 17.77057  1.000 48.97599 ? 107 GLY   A N   1 
ATOM   826  C  CA  . GLY   A 1 107 ? -24.71464 -41.21052 18.78223  1.000 55.70140 ? 107 GLY   A CA  1 
ATOM   827  C  C   . GLY   A 1 107 ? -23.80722 -39.99515 18.77626  1.000 57.73866 ? 107 GLY   A C   1 
ATOM   828  O  O   . GLY   A 1 107 ? -23.21275 -39.67543 19.81322  1.000 65.78772 ? 107 GLY   A O   1 
ATOM   829  N  N   A ARG   A 1 108 ? -23.67676 -39.31560 17.63918  0.474 53.27163 ? 108 ARG   A N   1 
ATOM   830  N  N   B ARG   A 1 108 ? -23.67609 -39.31454 17.63928  0.526 55.27940 ? 108 ARG   A N   1 
ATOM   831  C  CA  A ARG   A 1 108 ? -22.82921 -38.13633 17.55140  0.474 56.00898 ? 108 ARG   A CA  1 
ATOM   832  C  CA  B ARG   A 1 108 ? -22.82731 -38.13509 17.54671  0.526 54.54647 ? 108 ARG   A CA  1 
ATOM   833  C  C   A ARG   A 1 108 ? -23.67325 -36.87561 17.69901  0.474 54.19130 ? 108 ARG   A C   1 
ATOM   834  C  C   B ARG   A 1 108 ? -23.66653 -36.87145 17.68884  0.526 55.79831 ? 108 ARG   A C   1 
ATOM   835  O  O   A ARG   A 1 108 ? -24.77204 -36.77429 17.14272  0.474 50.71911 ? 108 ARG   A O   1 
ATOM   836  O  O   B ARG   A 1 108 ? -24.74530 -36.75491 17.09838  0.526 52.76087 ? 108 ARG   A O   1 
ATOM   837  C  CB  A ARG   A 1 108 ? -22.03057 -38.11420 16.24102  0.474 55.33606 ? 108 ARG   A CB  1 
ATOM   838  C  CB  B ARG   A 1 108 ? -22.04540 -38.10647 16.22966  0.526 57.42174 ? 108 ARG   A CB  1 
ATOM   839  C  CG  A ARG   A 1 108 ? -22.78630 -37.69195 14.99304  0.474 55.79024 ? 108 ARG   A CG  1 
ATOM   840  C  CG  B ARG   A 1 108 ? -22.87011 -38.39310 14.99768  0.526 56.04648 ? 108 ARG   A CG  1 
ATOM   841  C  CD  A ARG   A 1 108 ? -21.84558 -37.60325 13.79065  0.474 54.83711 ? 108 ARG   A CD  1 
ATOM   842  C  CD  B ARG   A 1 108 ? -22.22455 -37.83235 13.73562  0.526 55.54712 ? 108 ARG   A CD  1 
ATOM   843  N  NE  A ARG   A 1 108 ? -22.03117 -38.71507 12.86447  0.474 53.82414 ? 108 ARG   A NE  1 
ATOM   844  N  NE  B ARG   A 1 108 ? -21.35877 -38.80486 13.07854  0.526 54.18776 ? 108 ARG   A NE  1 
ATOM   845  C  CZ  A ARG   A 1 108 ? -21.08120 -39.21138 12.08266  0.474 52.63447 ? 108 ARG   A CZ  1 
ATOM   846  C  CZ  B ARG   A 1 108 ? -21.78970 -39.85140 12.38574  0.526 53.52753 ? 108 ARG   A CZ  1 
ATOM   847  N  NH1 A ARG   A 1 108 ? -19.85806 -38.70690 12.07378  0.474 52.97757 ? 108 ARG   A NH1 1 
ATOM   848  N  NH1 B ARG   A 1 108 ? -23.08202 -40.10314 12.24083  0.526 48.29741 ? 108 ARG   A NH1 1 
ATOM   849  N  NH2 A ARG   A 1 108 ? -21.36471 -40.24346 11.29256  0.474 49.13833 ? 108 ARG   A NH2 1 
ATOM   850  N  NH2 B ARG   A 1 108 ? -20.90145 -40.66950 11.82833  0.526 48.66082 ? 108 ARG   A NH2 1 
ATOM   851  N  N   . GLU   A 1 109 ? -23.16303 -35.93055 18.48271  1.000 50.54032 ? 109 GLU   A N   1 
ATOM   852  C  CA  . GLU   A 1 109 ? -23.86605 -34.68894 18.77391  1.000 54.06616 ? 109 GLU   A CA  1 
ATOM   853  C  C   . GLU   A 1 109 ? -23.51947 -33.66677 17.69822  1.000 50.72691 ? 109 GLU   A C   1 
ATOM   854  O  O   . GLU   A 1 109 ? -22.33811 -33.38026 17.46447  1.000 51.58029 ? 109 GLU   A O   1 
ATOM   855  C  CB  . GLU   A 1 109 ? -23.48364 -34.17649 20.16325  1.000 54.73469 ? 109 GLU   A CB  1 
ATOM   856  C  CG  . GLU   A 1 109 ? -24.46240 -34.56048 21.26718  1.000 59.67646 ? 109 GLU   A CG  1 
ATOM   857  N  N   . VAL   A 1 110 ? -24.54300 -33.12420 17.04207  1.000 44.44157 ? 110 VAL   A N   1 
ATOM   858  C  CA  . VAL   A 1 110 ? -24.36554 -32.24312 15.89335  1.000 41.84345 ? 110 VAL   A CA  1 
ATOM   859  C  C   . VAL   A 1 110 ? -25.12096 -30.94407 16.13185  1.000 44.48503 ? 110 VAL   A C   1 
ATOM   860  O  O   . VAL   A 1 110 ? -26.31855 -30.96093 16.44353  1.000 40.30096 ? 110 VAL   A O   1 
ATOM   861  C  CB  . VAL   A 1 110 ? -24.85072 -32.90211 14.58814  1.000 41.37228 ? 110 VAL   A CB  1 
ATOM   862  C  CG1 . VAL   A 1 110 ? -24.58105 -31.98381 13.40585  1.000 37.40301 ? 110 VAL   A CG1 1 
ATOM   863  C  CG2 . VAL   A 1 110 ? -24.17474 -34.24837 14.39375  1.000 47.41705 ? 110 VAL   A CG2 1 
ATOM   864  N  N   . LEU   A 1 111 ? -24.42732 -29.82350 15.96764  1.000 37.62985 ? 111 LEU   A N   1 
ATOM   865  C  CA  . LEU   A 1 111 ? -25.06141 -28.51324 15.95550  1.000 39.77132 ? 111 LEU   A CA  1 
ATOM   866  C  C   . LEU   A 1 111 ? -25.56364 -28.22187 14.54548  1.000 36.70935 ? 111 LEU   A C   1 
ATOM   867  O  O   . LEU   A 1 111 ? -24.83515 -28.43626 13.57013  1.000 36.13495 ? 111 LEU   A O   1 
ATOM   868  C  CB  . LEU   A 1 111 ? -24.06743 -27.43797 16.40281  1.000 37.57630 ? 111 LEU   A CB  1 
ATOM   869  C  CG  . LEU   A 1 111 ? -24.44621 -25.97164 16.17781  1.000 39.93049 ? 111 LEU   A CG  1 
ATOM   870  C  CD1 . LEU   A 1 111 ? -25.66855 -25.58007 17.00653  1.000 39.07864 ? 111 LEU   A CD1 1 
ATOM   871  C  CD2 . LEU   A 1 111 ? -23.26115 -25.07190 16.49965  1.000 39.29859 ? 111 LEU   A CD2 1 
ATOM   872  N  N   . ILE   A 1 112 ? -26.80826 -27.75293 14.43358  1.000 32.54707 ? 112 ILE   A N   1 
ATOM   873  C  CA  . ILE   A 1 112 ? -27.37329 -27.34084 13.15344  1.000 34.94943 ? 112 ILE   A CA  1 
ATOM   874  C  C   . ILE   A 1 112 ? -27.83738 -25.89396 13.26497  1.000 37.85606 ? 112 ILE   A C   1 
ATOM   875  O  O   . ILE   A 1 112 ? -28.31133 -25.45874 14.32098  1.000 35.01851 ? 112 ILE   A O   1 
ATOM   876  C  CB  . ILE   A 1 112 ? -28.53452 -28.25514 12.69996  1.000 32.97620 ? 112 ILE   A CB  1 
ATOM   877  C  CG1 . ILE   A 1 112 ? -29.68152 -28.21711 13.71017  1.000 34.12146 ? 112 ILE   A CG1 1 
ATOM   878  C  CG2 . ILE   A 1 112 ? -28.03322 -29.68952 12.47820  1.000 32.77957 ? 112 ILE   A CG2 1 
ATOM   879  C  CD1 . ILE   A 1 112 ? -30.99552 -28.80287 13.18499  1.000 33.75018 ? 112 ILE   A CD1 1 
ATOM   880  N  N   . MET   A 1 113 ? -27.67414 -25.14795 12.17643  1.000 31.75562 ? 113 MET   A N   1 
ATOM   881  C  CA  . MET   A 1 113 ? -28.14352 -23.77086 12.07631  1.000 33.25330 ? 113 MET   A CA  1 
ATOM   882  C  C   . MET   A 1 113 ? -28.13114 -23.38891 10.60752  1.000 35.38611 ? 113 MET   A C   1 
ATOM   883  O  O   . MET   A 1 113 ? -27.56959 -24.09993 9.77150   1.000 33.89696 ? 113 MET   A O   1 
ATOM   884  C  CB  . MET   A 1 113 ? -27.28929 -22.78413 12.89128  1.000 36.52300 ? 113 MET   A CB  1 
ATOM   885  C  CG  . MET   A 1 113 ? -25.82408 -22.63930 12.49190  1.000 40.35339 ? 113 MET   A CG  1 
ATOM   886  S  SD  . MET   A 1 113 ? -24.69381 -22.36431 13.90150  1.000 43.30699 ? 113 MET   A SD  1 
ATOM   887  C  CE  . MET   A 1 113 ? -24.88330 -20.58739 14.00113  1.000 41.49136 ? 113 MET   A CE  1 
ATOM   888  N  N   . HIS   A 1 114 ? -28.75740 -22.25048 10.29640  1.000 32.77410 ? 114 HIS   A N   1 
ATOM   889  C  CA  . HIS   A 1 114 ? -28.76614 -21.80890 8.90609   1.000 32.56295 ? 114 HIS   A CA  1 
ATOM   890  C  C   . HIS   A 1 114 ? -27.37326 -21.39333 8.45008   1.000 33.96605 ? 114 HIS   A C   1 
ATOM   891  O  O   . HIS   A 1 114 ? -26.95104 -21.72350 7.33316   1.000 32.54498 ? 114 HIS   A O   1 
ATOM   892  C  CB  . HIS   A 1 114 ? -29.73988 -20.65563 8.70819   1.000 31.88987 ? 114 HIS   A CB  1 
ATOM   893  C  CG  . HIS   A 1 114 ? -29.72056 -20.11259 7.31877   1.000 34.28457 ? 114 HIS   A CG  1 
ATOM   894  N  ND1 . HIS   A 1 114 ? -30.01092 -20.88918 6.21661   1.000 33.35134 ? 114 HIS   A ND1 1 
ATOM   895  C  CD2 . HIS   A 1 114 ? -29.38917 -18.88812 6.84332   1.000 34.98607 ? 114 HIS   A CD2 1 
ATOM   896  C  CE1 . HIS   A 1 114 ? -29.88855 -20.15723 5.12361   1.000 34.55586 ? 114 HIS   A CE1 1 
ATOM   897  N  NE2 . HIS   A 1 114 ? -29.51271 -18.93928 5.47682   1.000 35.01303 ? 114 HIS   A NE2 1 
ATOM   898  N  N   . GLY   A 1 115 ? -26.65110 -20.65597 9.28896   1.000 33.96937 ? 115 GLY   A N   1 
ATOM   899  C  CA  . GLY   A 1 115 ? -25.28164 -20.27328 9.01265   1.000 32.13777 ? 115 GLY   A CA  1 
ATOM   900  C  C   . GLY   A 1 115 ? -25.05281 -18.78418 8.86310   1.000 35.75729 ? 115 GLY   A C   1 
ATOM   901  O  O   . GLY   A 1 115 ? -23.89822 -18.34257 8.95301   1.000 39.30041 ? 115 GLY   A O   1 
ATOM   902  N  N   . ASP   A 1 116 ? -26.10837 -17.98932 8.64067   1.000 35.96247 ? 116 ASP   A N   1 
ATOM   903  C  CA  . ASP   A 1 116 ? -25.89001 -16.55778 8.43268   1.000 38.22574 ? 116 ASP   A CA  1 
ATOM   904  C  C   . ASP   A 1 116 ? -25.32872 -15.88814 9.68119   1.000 37.59175 ? 116 ASP   A C   1 
ATOM   905  O  O   . ASP   A 1 116 ? -24.53113 -14.95065 9.57070   1.000 40.94050 ? 116 ASP   A O   1 
ATOM   906  C  CB  . ASP   A 1 116 ? -27.17819 -15.85742 7.97655   1.000 39.29188 ? 116 ASP   A CB  1 
ATOM   907  C  CG  . ASP   A 1 116 ? -28.30448 -15.95253 8.99163   1.000 40.64238 ? 116 ASP   A CG  1 
ATOM   908  O  OD1 . ASP   A 1 116 ? -28.58572 -17.05800 9.49578   1.000 41.09783 ? 116 ASP   A OD1 1 
ATOM   909  O  OD2 . ASP   A 1 116 ? -28.91857 -14.90758 9.28380   1.000 39.03698 ? 116 ASP   A OD2 1 
ATOM   910  N  N   . THR   A 1 117 ? -25.69827 -16.36840 10.87081  1.000 37.99104 ? 117 THR   A N   1 
ATOM   911  C  CA  . THR   A 1 117 ? -25.18209 -15.78339 12.10494  1.000 38.79723 ? 117 THR   A CA  1 
ATOM   912  C  C   . THR   A 1 117 ? -23.69486 -16.04402 12.31046  1.000 41.02106 ? 117 THR   A C   1 
ATOM   913  O  O   . THR   A 1 117 ? -23.10837 -15.46277 13.22750  1.000 41.18762 ? 117 THR   A O   1 
ATOM   914  C  CB  . THR   A 1 117 ? -25.96567 -16.31215 13.31043  1.000 44.71391 ? 117 THR   A CB  1 
ATOM   915  O  OG1 . THR   A 1 117 ? -25.78918 -17.72917 13.40507  1.000 40.30085 ? 117 THR   A OG1 1 
ATOM   916  C  CG2 . THR   A 1 117 ? -27.45486 -16.00596 13.16524  1.000 39.81777 ? 117 THR   A CG2 1 
ATOM   917  N  N   . LEU   A 1 118 ? -23.07428 -16.89697 11.49317  1.000 37.72694 ? 118 LEU   A N   1 
ATOM   918  C  CA  . LEU   A 1 118 ? -21.63617 -17.12945 11.55335  1.000 38.94854 ? 118 LEU   A CA  1 
ATOM   919  C  C   . LEU   A 1 118 ? -20.83547 -16.14074 10.71749  1.000 45.19016 ? 118 LEU   A C   1 
ATOM   920  O  O   . LEU   A 1 118 ? -19.60553 -16.10484 10.83567  1.000 44.04755 ? 118 LEU   A O   1 
ATOM   921  C  CB  . LEU   A 1 118 ? -21.31082 -18.55099 11.08063  1.000 38.19268 ? 118 LEU   A CB  1 
ATOM   922  C  CG  . LEU   A 1 118 ? -22.01252 -19.67578 11.84565  1.000 38.87567 ? 118 LEU   A CG  1 
ATOM   923  C  CD1 . LEU   A 1 118 ? -21.79603 -21.01834 11.15357  1.000 41.78876 ? 118 LEU   A CD1 1 
ATOM   924  C  CD2 . LEU   A 1 118 ? -21.51497 -19.72470 13.27614  1.000 40.94490 ? 118 LEU   A CD2 1 
ATOM   925  N  N   . CYS   A 1 119 ? -21.49293 -15.35272 9.87222   1.000 41.26723 ? 119 CYS   A N   1 
ATOM   926  C  CA  . CYS   A 1 119 ? -20.79618 -14.46009 8.94882   1.000 46.58444 ? 119 CYS   A CA  1 
ATOM   927  C  C   . CYS   A 1 119 ? -20.64890 -13.06812 9.56586   1.000 49.56662 ? 119 CYS   A C   1 
ATOM   928  O  O   . CYS   A 1 119 ? -21.11088 -12.05927 9.03339   1.000 53.33693 ? 119 CYS   A O   1 
ATOM   929  C  CB  . CYS   A 1 119 ? -21.53315 -14.41195 7.61364   1.000 47.65976 ? 119 CYS   A CB  1 
ATOM   930  S  SG  . CYS   A 1 119 ? -21.80996 -16.03928 6.85633   1.000 46.96359 ? 119 CYS   A SG  1 
ATOM   931  N  N   . THR   A 1 120 ? -19.96780 -13.03510 10.71570  1.000 49.61736 ? 120 THR   A N   1 
ATOM   932  C  CA  . THR   A 1 120 ? -19.85228 -11.82504 11.52355  1.000 52.80433 ? 120 THR   A CA  1 
ATOM   933  C  C   . THR   A 1 120 ? -18.95908 -10.75965 10.89551  1.000 58.59606 ? 120 THR   A C   1 
ATOM   934  O  O   . THR   A 1 120 ? -18.83926 -9.67187  11.47010  1.000 58.23195 ? 120 THR   A O   1 
ATOM   935  C  CB  . THR   A 1 120 ? -19.32802 -12.17173 12.92064  1.000 52.51369 ? 120 THR   A CB  1 
ATOM   936  O  OG1 . THR   A 1 120 ? -18.07219 -12.85266 12.80602  1.000 49.79856 ? 120 THR   A OG1 1 
ATOM   937  C  CG2 . THR   A 1 120 ? -20.31964 -13.06923 13.65636  1.000 48.97960 ? 120 THR   A CG2 1 
ATOM   938  N  N   . ASP   A 1 121 ? -18.33467 -11.03281 9.74912   1.000 54.39413 ? 121 ASP   A N   1 
ATOM   939  C  CA  . ASP   A 1 121 ? -17.55948 -10.02194 9.04158   1.000 58.44054 ? 121 ASP   A CA  1 
ATOM   940  C  C   . ASP   A 1 121 ? -18.41730 -9.14266  8.14110   1.000 59.18801 ? 121 ASP   A C   1 
ATOM   941  O  O   . ASP   A 1 121 ? -17.93409 -8.10479  7.67530   1.000 57.37017 ? 121 ASP   A O   1 
ATOM   942  C  CB  . ASP   A 1 121 ? -16.45686 -10.69255 8.21840   1.000 57.51330 ? 121 ASP   A CB  1 
ATOM   943  C  CG  . ASP   A 1 121 ? -15.44425 -11.41098 9.08546   1.000 61.89927 ? 121 ASP   A CG  1 
ATOM   944  O  OD1 . ASP   A 1 121 ? -14.93641 -10.79044 10.04273  1.000 63.81976 ? 121 ASP   A OD1 1 
ATOM   945  O  OD2 . ASP   A 1 121 ? -15.18758 -12.60887 8.83860   1.000 60.14123 ? 121 ASP   A OD2 1 
ATOM   946  N  N   . ASP   A 1 122 ? -19.66836 -9.52745  7.88409   1.000 54.18111 ? 122 ASP   A N   1 
ATOM   947  C  CA  . ASP   A 1 122 ? -20.60200 -8.69706  7.12605   1.000 57.63147 ? 122 ASP   A CA  1 
ATOM   948  C  C   . ASP   A 1 122 ? -21.46178 -7.92983  8.12748   1.000 57.67103 ? 122 ASP   A C   1 
ATOM   949  O  O   . ASP   A 1 122 ? -22.61351 -8.26736  8.40053   1.000 53.10650 ? 122 ASP   A O   1 
ATOM   950  C  CB  . ASP   A 1 122 ? -21.44251 -9.54990  6.17482   1.000 56.30213 ? 122 ASP   A CB  1 
ATOM   951  C  CG  . ASP   A 1 122 ? -22.13933 -8.72145  5.10448   1.000 55.79871 ? 122 ASP   A CG  1 
ATOM   952  O  OD1 . ASP   A 1 122 ? -22.37475 -7.51567  5.33507   1.000 57.13570 ? 122 ASP   A OD1 1 
ATOM   953  O  OD2 . ASP   A 1 122 ? -22.44710 -9.27395  4.02694   1.000 55.54807 ? 122 ASP   A OD2 1 
ATOM   954  N  N   . GLN   A 1 123 ? -20.87576 -6.87018  8.68440   1.000 57.92616 ? 123 GLN   A N   1 
ATOM   955  C  CA  . GLN   A 1 123 ? -21.59862 -6.05641  9.65223   1.000 61.45824 ? 123 GLN   A CA  1 
ATOM   956  C  C   . GLN   A 1 123 ? -22.76763 -5.31659  9.01735   1.000 57.12236 ? 123 GLN   A C   1 
ATOM   957  O  O   . GLN   A 1 123 ? -23.71124 -4.94841  9.72645   1.000 58.56591 ? 123 GLN   A O   1 
ATOM   958  C  CB  . GLN   A 1 123 ? -20.63768 -5.08145  10.33063  1.000 70.74384 ? 123 GLN   A CB  1 
ATOM   959  C  CG  . GLN   A 1 123 ? -19.44364 -5.78005  10.96972  1.000 75.84919 ? 123 GLN   A CG  1 
ATOM   960  C  CD  . GLN   A 1 123 ? -19.61567 -5.98572  12.46478  1.000 87.56718 ? 123 GLN   A CD  1 
ATOM   961  O  OE1 . GLN   A 1 123 ? -20.52734 -5.43137  13.08020  1.000 85.35513 ? 123 GLN   A OE1 1 
ATOM   962  N  NE2 . GLN   A 1 123 ? -18.74801 -6.80215  13.05276  1.000 94.26812 ? 123 GLN   A NE2 1 
ATOM   963  N  N   . GLY   A 1 124 ? -22.73681 -5.10671  7.69919   1.000 59.15771 ? 124 GLY   A N   1 
ATOM   964  C  CA  . GLY   A 1 124 ? -23.89769 -4.54719  7.02636   1.000 47.85803 ? 124 GLY   A CA  1 
ATOM   965  C  C   . GLY   A 1 124 ? -25.07856 -5.50075  7.02456   1.000 55.25814 ? 124 GLY   A C   1 
ATOM   966  O  O   . GLY   A 1 124 ? -26.22394 -5.08788  7.23541   1.000 53.33739 ? 124 GLY   A O   1 
ATOM   967  N  N   . TYR   A 1 125 ? -24.82395 -6.78975  6.78574   1.000 53.87418 ? 125 TYR   A N   1 
ATOM   968  C  CA  . TYR   A 1 125 ? -25.91509 -7.75350  6.86658   1.000 50.96355 ? 125 TYR   A CA  1 
ATOM   969  C  C   . TYR   A 1 125 ? -26.38920 -7.92128  8.30418   1.000 49.87421 ? 125 TYR   A C   1 
ATOM   970  O  O   . TYR   A 1 125 ? -27.59294 -8.02793  8.55662   1.000 51.26979 ? 125 TYR   A O   1 
ATOM   971  C  CB  . TYR   A 1 125 ? -25.50735 -9.11347  6.29489   1.000 52.50758 ? 125 TYR   A CB  1 
ATOM   972  C  CG  . TYR   A 1 125 ? -26.51035 -10.17690 6.69328   1.000 46.12777 ? 125 TYR   A CG  1 
ATOM   973  C  CD1 . TYR   A 1 125 ? -27.80210 -10.14679 6.18497   1.000 47.77762 ? 125 TYR   A CD1 1 
ATOM   974  C  CD2 . TYR   A 1 125 ? -26.18268 -11.17959 7.59732   1.000 44.37669 ? 125 TYR   A CD2 1 
ATOM   975  C  CE1 . TYR   A 1 125 ? -28.73996 -11.08672 6.55417   1.000 44.69999 ? 125 TYR   A CE1 1 
ATOM   976  C  CE2 . TYR   A 1 125 ? -27.11552 -12.13184 7.97320   1.000 45.95006 ? 125 TYR   A CE2 1 
ATOM   977  C  CZ  . TYR   A 1 125 ? -28.39224 -12.07650 7.44770   1.000 45.67327 ? 125 TYR   A CZ  1 
ATOM   978  O  OH  . TYR   A 1 125 ? -29.33253 -13.00780 7.81130   1.000 45.57939 ? 125 TYR   A OH  1 
ATOM   979  N  N   . LEU   A 1 126 ? -25.45831 -7.94682  9.26009   1.000 49.58919 ? 126 LEU   A N   1 
ATOM   980  C  CA  . LEU   A 1 126 ? -25.84120 -8.17349  10.64932  1.000 54.44029 ? 126 LEU   A CA  1 
ATOM   981  C  C   . LEU   A 1 126 ? -26.73321 -7.05339  11.17062  1.000 54.73642 ? 126 LEU   A C   1 
ATOM   982  O  O   . LEU   A 1 126 ? -27.65543 -7.30424  11.95682  1.000 53.20792 ? 126 LEU   A O   1 
ATOM   983  C  CB  . LEU   A 1 126 ? -24.59607 -8.33107  11.51805  1.000 55.41130 ? 126 LEU   A CB  1 
ATOM   984  C  CG  . LEU   A 1 126 ? -23.96689 -9.72780  11.47286  1.000 56.96813 ? 126 LEU   A CG  1 
ATOM   985  C  CD1 . LEU   A 1 126 ? -23.06264 -9.93433  12.66865  1.000 61.33966 ? 126 LEU   A CD1 1 
ATOM   986  C  CD2 . LEU   A 1 126 ? -25.03875 -10.81217 11.42142  1.000 61.04213 ? 126 LEU   A CD2 1 
ATOM   987  N  N   . ALA   A 1 127 ? -26.48015 -5.81191  10.74006  1.000 50.90329 ? 127 ALA   A N   1 
ATOM   988  C  CA  . ALA   A 1 127 ? -27.38655 -4.71528  11.07202  1.000 49.64877 ? 127 ALA   A CA  1 
ATOM   989  C  C   . ALA   A 1 127 ? -28.77110 -4.95439  10.48311  1.000 51.85494 ? 127 ALA   A C   1 
ATOM   990  O  O   . ALA   A 1 127 ? -29.78970 -4.78371  11.16441  1.000 55.24421 ? 127 ALA   A O   1 
ATOM   991  C  CB  . ALA   A 1 127 ? -26.81659 -3.38935  10.57208  1.000 51.72533 ? 127 ALA   A CB  1 
ATOM   992  N  N   . PHE   A 1 128 ? -28.82754 -5.34227  9.20709   1.000 48.31180 ? 128 PHE   A N   1 
ATOM   993  C  CA  . PHE   A 1 128 ? -30.10794 -5.66639  8.58752   1.000 48.82078 ? 128 PHE   A CA  1 
ATOM   994  C  C   . PHE   A 1 128 ? -30.79482 -6.80870  9.32605   1.000 45.11753 ? 128 PHE   A C   1 
ATOM   995  O  O   . PHE   A 1 128 ? -31.99359 -6.74102  9.61949   1.000 48.90409 ? 128 PHE   A O   1 
ATOM   996  C  CB  . PHE   A 1 128 ? -29.89869 -6.01765  7.11337   1.000 47.66044 ? 128 PHE   A CB  1 
ATOM   997  C  CG  . PHE   A 1 128 ? -31.11017 -6.61144  6.44954   1.000 50.85380 ? 128 PHE   A CG  1 
ATOM   998  C  CD1 . PHE   A 1 128 ? -32.07458 -5.79518  5.88451   1.000 53.61000 ? 128 PHE   A CD1 1 
ATOM   999  C  CD2 . PHE   A 1 128 ? -31.28369 -7.98547  6.38770   1.000 45.44605 ? 128 PHE   A CD2 1 
ATOM   1000 C  CE1 . PHE   A 1 128 ? -33.18857 -6.34008  5.27135   1.000 46.69793 ? 128 PHE   A CE1 1 
ATOM   1001 C  CE2 . PHE   A 1 128 ? -32.39349 -8.53315  5.77866   1.000 47.45244 ? 128 PHE   A CE2 1 
ATOM   1002 C  CZ  . PHE   A 1 128 ? -33.34495 -7.70912  5.21755   1.000 48.23110 ? 128 PHE   A CZ  1 
ATOM   1003 N  N   . ARG   A 1 129 ? -30.04589 -7.87230  9.63494   1.000 46.00347 ? 129 ARG   A N   1 
ATOM   1004 C  CA  . ARG   A 1 129 ? -30.63211 -9.00211  10.34954  1.000 47.51454 ? 129 ARG   A CA  1 
ATOM   1005 C  C   . ARG   A 1 129 ? -31.19498 -8.57397  11.69832  1.000 45.52033 ? 129 ARG   A C   1 
ATOM   1006 O  O   . ARG   A 1 129 ? -32.30910 -8.96605  12.06616  1.000 45.90734 ? 129 ARG   A O   1 
ATOM   1007 C  CB  . ARG   A 1 129 ? -29.59792 -10.10971 10.54553  1.000 45.95815 ? 129 ARG   A CB  1 
ATOM   1008 C  CG  . ARG   A 1 129 ? -30.18867 -11.34993 11.20346  1.000 46.56102 ? 129 ARG   A CG  1 
ATOM   1009 C  CD  . ARG   A 1 129 ? -29.11794 -12.36593 11.57535  1.000 43.43737 ? 129 ARG   A CD  1 
ATOM   1010 N  NE  . ARG   A 1 129 ? -29.71291 -13.65980 11.89504  1.000 46.81367 ? 129 ARG   A NE  1 
ATOM   1011 C  CZ  . ARG   A 1 129 ? -30.29500 -13.95756 13.04903  1.000 47.98076 ? 129 ARG   A CZ  1 
ATOM   1012 N  NH1 . ARG   A 1 129 ? -30.35409 -13.08303 14.03936  1.000 47.22730 ? 129 ARG   A NH1 1 
ATOM   1013 N  NH2 . ARG   A 1 129 ? -30.81959 -15.16872 13.21744  1.000 47.06089 ? 129 ARG   A NH2 1 
ATOM   1014 N  N   . ALA   A 1 130 ? -30.43485 -7.77448  12.45102  1.000 45.48906 ? 130 ALA   A N   1 
ATOM   1015 C  CA  . ALA   A 1 130 ? -30.90310 -7.32398  13.75727  1.000 49.61187 ? 130 ALA   A CA  1 
ATOM   1016 C  C   . ALA   A 1 130 ? -32.22539 -6.57771  13.64191  1.000 51.10187 ? 130 ALA   A C   1 
ATOM   1017 O  O   . ALA   A 1 130 ? -33.11605 -6.74497  14.48404  1.000 52.08928 ? 130 ALA   A O   1 
ATOM   1018 C  CB  . ALA   A 1 130 ? -29.84674 -6.43956  14.41997  1.000 47.14341 ? 130 ALA   A CB  1 
ATOM   1019 N  N   . LYS   A 1 131 ? -32.37505 -5.75683  12.59977  1.000 48.96589 ? 131 LYS   A N   1 
ATOM   1020 C  CA  . LYS   A 1 131 ? -33.60675 -4.99248  12.42268  1.000 50.13943 ? 131 LYS   A CA  1 
ATOM   1021 C  C   . LYS   A 1 131 ? -34.79159 -5.91166  12.14735  1.000 46.24675 ? 131 LYS   A C   1 
ATOM   1022 O  O   . LYS   A 1 131 ? -35.79541 -5.88446  12.86861  1.000 44.37802 ? 131 LYS   A O   1 
ATOM   1023 C  CB  . LYS   A 1 131 ? -33.44161 -3.98032  11.28747  1.000 50.78187 ? 131 LYS   A CB  1 
ATOM   1024 C  CG  . LYS   A 1 131 ? -33.14444 -2.56100  11.74705  1.000 62.78883 ? 131 LYS   A CG  1 
ATOM   1025 C  CD  . LYS   A 1 131 ? -31.65357 -2.28862  11.76640  1.000 61.57648 ? 131 LYS   A CD  1 
ATOM   1026 C  CE  . LYS   A 1 131 ? -31.34873 -0.88457  12.24907  1.000 64.65698 ? 131 LYS   A CE  1 
ATOM   1027 N  NZ  . LYS   A 1 131 ? -31.33945 -0.80888  13.73553  1.000 71.48250 ? 131 LYS   A NZ  1 
ATOM   1028 N  N   . VAL   A 1 132 ? -34.69548 -6.73870  11.10031  1.000 47.21951 ? 132 VAL   A N   1 
ATOM   1029 C  CA  . VAL   A 1 132 ? -35.84995 -7.53689  10.68522  1.000 44.48063 ? 132 VAL   A CA  1 
ATOM   1030 C  C   . VAL   A 1 132 ? -36.11053 -8.72509  11.59439  1.000 40.01103 ? 132 VAL   A C   1 
ATOM   1031 O  O   . VAL   A 1 132 ? -37.12744 -9.40584  11.42344  1.000 41.27873 ? 132 VAL   A O   1 
ATOM   1032 C  CB  . VAL   A 1 132 ? -35.72146 -8.04235  9.23382   1.000 39.32060 ? 132 VAL   A CB  1 
ATOM   1033 C  CG1 . VAL   A 1 132 ? -35.68015 -6.86783  8.26528   1.000 40.68823 ? 132 VAL   A CG1 1 
ATOM   1034 C  CG2 . VAL   A 1 132 ? -34.50097 -8.94510  9.05991   1.000 42.00988 ? 132 VAL   A CG2 1 
ATOM   1035 N  N   . HIS   A 1 133 ? -35.23610 -8.99169  12.55945  1.000 41.53354 ? 133 HIS   A N   1 
ATOM   1036 C  CA  . HIS   A 1 133 ? -35.48225 -10.01513 13.56572  1.000 43.64054 ? 133 HIS   A CA  1 
ATOM   1037 C  C   . HIS   A 1 133 ? -35.94917 -9.42510  14.88800  1.000 49.45946 ? 133 HIS   A C   1 
ATOM   1038 O  O   . HIS   A 1 133 ? -36.16854 -10.17455 15.84522  1.000 49.24109 ? 133 HIS   A O   1 
ATOM   1039 C  CB  . HIS   A 1 133 ? -34.22137 -10.86091 13.78539  1.000 42.36134 ? 133 HIS   A CB  1 
ATOM   1040 C  CG  . HIS   A 1 133 ? -34.07814 -11.98825 12.81079  1.000 45.61475 ? 133 HIS   A CG  1 
ATOM   1041 N  ND1 . HIS   A 1 133 ? -33.59344 -11.80794 11.53262  1.000 45.83025 ? 133 HIS   A ND1 1 
ATOM   1042 C  CD2 . HIS   A 1 133 ? -34.35328 -13.30902 12.92581  1.000 42.42534 ? 133 HIS   A CD2 1 
ATOM   1043 C  CE1 . HIS   A 1 133 ? -33.58075 -12.96742 10.90066  1.000 43.07311 ? 133 HIS   A CE1 1 
ATOM   1044 N  NE2 . HIS   A 1 133 ? -34.03566 -13.89455 11.72445  1.000 47.47996 ? 133 HIS   A NE2 1 
ATOM   1045 N  N   . THR   A 1 134 ? -36.09848 -8.10815  14.96587  1.000 44.90419 ? 134 THR   A N   1 
ATOM   1046 C  CA  . THR   A 1 134 ? -36.66229 -7.48849  16.15483  1.000 50.24865 ? 134 THR   A CA  1 
ATOM   1047 C  C   . THR   A 1 134 ? -38.14978 -7.81260  16.20579  1.000 46.00940 ? 134 THR   A C   1 
ATOM   1048 O  O   . THR   A 1 134 ? -38.86274 -7.54629  15.22937  1.000 46.78424 ? 134 THR   A O   1 
ATOM   1049 C  CB  . THR   A 1 134 ? -36.43068 -5.97773  16.13155  1.000 47.15223 ? 134 THR   A CB  1 
ATOM   1050 O  OG1 . THR   A 1 134 ? -35.02182 -5.71503  16.06436  1.000 47.38395 ? 134 THR   A OG1 1 
ATOM   1051 C  CG2 . THR   A 1 134 ? -36.99148 -5.33549  17.39070  1.000 49.24310 ? 134 THR   A CG2 1 
ATOM   1052 N  N   . PRO   A 1 135 ? -38.65688 -8.39474  17.29721  1.000 49.73114 ? 135 PRO   A N   1 
ATOM   1053 C  CA  . PRO   A 1 135 ? -40.05684 -8.85955  17.29070  1.000 47.67974 ? 135 PRO   A CA  1 
ATOM   1054 C  C   . PRO   A 1 135 ? -41.08007 -7.76353  17.03114  1.000 49.70416 ? 135 PRO   A C   1 
ATOM   1055 O  O   . PRO   A 1 135 ? -42.03858 -7.99570  16.28340  1.000 46.09991 ? 135 PRO   A O   1 
ATOM   1056 C  CB  . PRO   A 1 135 ? -40.22288 -9.46953  18.68891  1.000 52.76248 ? 135 PRO   A CB  1 
ATOM   1057 C  CG  . PRO   A 1 135 ? -38.85105 -9.88203  19.08088  1.000 52.78006 ? 135 PRO   A CG  1 
ATOM   1058 C  CD  . PRO   A 1 135 ? -37.93316 -8.83523  18.50172  1.000 50.96522 ? 135 PRO   A CD  1 
ATOM   1059 N  N   . TRP   A 1 136 ? -40.92037 -6.57445  17.62035  1.000 47.88744 ? 136 TRP   A N   1 
ATOM   1060 C  CA  . TRP   A 1 136 ? -41.93456 -5.54867  17.39986  1.000 50.02823 ? 136 TRP   A CA  1 
ATOM   1061 C  C   . TRP   A 1 136 ? -41.89249 -5.02183  15.97158  1.000 47.34549 ? 136 TRP   A C   1 
ATOM   1062 O  O   . TRP   A 1 136 ? -42.92036 -4.58097  15.44649  1.000 46.98087 ? 136 TRP   A O   1 
ATOM   1063 C  CB  . TRP   A 1 136 ? -41.79931 -4.41598  18.42354  1.000 50.62187 ? 136 TRP   A CB  1 
ATOM   1064 C  CG  . TRP   A 1 136 ? -40.58821 -3.52412  18.31022  1.000 52.96930 ? 136 TRP   A CG  1 
ATOM   1065 C  CD1 . TRP   A 1 136 ? -39.45073 -3.59025  19.06374  1.000 49.09238 ? 136 TRP   A CD1 1 
ATOM   1066 C  CD2 . TRP   A 1 136 ? -40.42099 -2.40188  17.43138  1.000 47.69014 ? 136 TRP   A CD2 1 
ATOM   1067 N  NE1 . TRP   A 1 136 ? -38.57769 -2.59493  18.69383  1.000 51.82259 ? 136 TRP   A NE1 1 
ATOM   1068 C  CE2 . TRP   A 1 136 ? -39.15043 -1.85159  17.69394  1.000 52.61248 ? 136 TRP   A CE2 1 
ATOM   1069 C  CE3 . TRP   A 1 136 ? -41.21511 -1.82083  16.43718  1.000 50.57620 ? 136 TRP   A CE3 1 
ATOM   1070 C  CZ2 . TRP   A 1 136 ? -38.65888 -0.74386  17.00231  1.000 52.75446 ? 136 TRP   A CZ2 1 
ATOM   1071 C  CZ3 . TRP   A 1 136 ? -40.72355 -0.72389  15.74965  1.000 46.80481 ? 136 TRP   A CZ3 1 
ATOM   1072 C  CH2 . TRP   A 1 136 ? -39.45896 -0.19754  16.03594  1.000 45.94290 ? 136 TRP   A CH2 1 
ATOM   1073 N  N   . ILE   A 1 137 ? -40.73363 -5.09281  15.31610  1.000 43.07674 ? 137 ILE   A N   1 
ATOM   1074 C  CA  . ILE   A 1 137 ? -40.65670 -4.70381  13.91151  1.000 44.18228 ? 137 ILE   A CA  1 
ATOM   1075 C  C   . ILE   A 1 137 ? -41.35388 -5.73674  13.03526  1.000 43.67065 ? 137 ILE   A C   1 
ATOM   1076 O  O   . ILE   A 1 137 ? -42.05283 -5.38720  12.07519  1.000 41.21962 ? 137 ILE   A O   1 
ATOM   1077 C  CB  . ILE   A 1 137 ? -39.18684 -4.49502  13.50032  1.000 47.57808 ? 137 ILE   A CB  1 
ATOM   1078 C  CG1 . ILE   A 1 137 ? -38.57024 -3.34923  14.31111  1.000 47.30273 ? 137 ILE   A CG1 1 
ATOM   1079 C  CG2 . ILE   A 1 137 ? -39.07331 -4.23137  12.00232  1.000 46.41228 ? 137 ILE   A CG2 1 
ATOM   1080 C  CD1 . ILE   A 1 137 ? -37.19803 -2.91549  13.82999  1.000 46.90070 ? 137 ILE   A CD1 1 
ATOM   1081 N  N   . GLN   A 1 138 ? -41.18070 -7.02369  13.35547  1.000 41.25303 ? 138 GLN   A N   1 
ATOM   1082 C  CA  . GLN   A 1 138 ? -41.87735 -8.07977  12.62709  1.000 38.50533 ? 138 GLN   A CA  1 
ATOM   1083 C  C   . GLN   A 1 138 ? -43.38324 -7.97084  12.79764  1.000 41.84810 ? 138 GLN   A C   1 
ATOM   1084 O  O   . GLN   A 1 138 ? -44.13654 -8.11813  11.82761  1.000 41.56527 ? 138 GLN   A O   1 
ATOM   1085 C  CB  . GLN   A 1 138 ? -41.40464 -9.45213  13.10785  1.000 37.85189 ? 138 GLN   A CB  1 
ATOM   1086 C  CG  . GLN   A 1 138 ? -39.96560 -9.75931  12.80364  1.000 39.82889 ? 138 GLN   A CG  1 
ATOM   1087 C  CD  . GLN   A 1 138 ? -39.62033 -11.19785 13.11972  1.000 44.87668 ? 138 GLN   A CD  1 
ATOM   1088 O  OE1 . GLN   A 1 138 ? -40.41532 -11.91711 13.72135  1.000 49.50523 ? 138 GLN   A OE1 1 
ATOM   1089 N  NE2 . GLN   A 1 138 ? -38.44863 -11.63195 12.69188  1.000 38.40044 ? 138 GLN   A NE2 1 
ATOM   1090 N  N   . ARG   A 1 139 ? -43.84214 -7.74107  14.03139  1.000 40.59047 ? 139 ARG   A N   1 
ATOM   1091 C  CA  . ARG   A 1 139 ? -45.27609 -7.62913  14.28276  1.000 41.25653 ? 139 ARG   A CA  1 
ATOM   1092 C  C   . ARG   A 1 139 ? -45.87733 -6.46248  13.51063  1.000 43.90266 ? 139 ARG   A C   1 
ATOM   1093 O  O   . ARG   A 1 139 ? -46.99302 -6.55905  12.98509  1.000 44.44141 ? 139 ARG   A O   1 
ATOM   1094 C  CB  . ARG   A 1 139 ? -45.53055 -7.46844  15.78392  1.000 47.59309 ? 139 ARG   A CB  1 
ATOM   1095 C  CG  . ARG   A 1 139 ? -45.17850 -8.69904  16.61235  1.000 54.02948 ? 139 ARG   A CG  1 
ATOM   1096 C  CD  . ARG   A 1 139 ? -45.72382 -8.60161  18.03719  1.000 60.19512 ? 139 ARG   A CD  1 
ATOM   1097 N  NE  . ARG   A 1 139 ? -44.66828 -8.57727  19.04565  1.000 71.58523 ? 139 ARG   A NE  1 
ATOM   1098 C  CZ  . ARG   A 1 139 ? -44.24039 -7.48529  19.66660  1.000 72.92363 ? 139 ARG   A CZ  1 
ATOM   1099 N  NH1 . ARG   A 1 139 ? -44.75559 -6.29498  19.40755  1.000 71.29921 ? 139 ARG   A NH1 1 
ATOM   1100 N  NH2 . ARG   A 1 139 ? -43.27607 -7.59160  20.57650  1.000 68.81557 ? 139 ARG   A NH2 1 
ATOM   1101 N  N   . LEU   A 1 140 ? -45.14885 -5.34999  13.43341  1.000 44.11918 ? 140 LEU   A N   1 
ATOM   1102 C  CA  . LEU   A 1 140 ? -45.60599 -4.20304  12.65678  1.000 41.25795 ? 140 LEU   A CA  1 
ATOM   1103 C  C   . LEU   A 1 140 ? -45.68132 -4.53745  11.16935  1.000 41.22622 ? 140 LEU   A C   1 
ATOM   1104 O  O   . LEU   A 1 140 ? -46.66745 -4.21479  10.49639  1.000 39.82388 ? 140 LEU   A O   1 
ATOM   1105 C  CB  . LEU   A 1 140 ? -44.66631 -3.02450  12.90294  1.000 41.31783 ? 140 LEU   A CB  1 
ATOM   1106 C  CG  . LEU   A 1 140 ? -44.97894 -1.69029  12.23306  1.000 49.96327 ? 140 LEU   A CG  1 
ATOM   1107 C  CD1 . LEU   A 1 140 ? -46.21480 -1.06761  12.85125  1.000 49.27561 ? 140 LEU   A CD1 1 
ATOM   1108 C  CD2 . LEU   A 1 140 ? -43.79157 -0.75392  12.36344  1.000 52.14560 ? 140 LEU   A CD2 1 
ATOM   1109 N  N   . PHE   A 1 141 ? -44.64499 -5.18929  10.63894  1.000 38.51454 ? 141 PHE   A N   1 
ATOM   1110 C  CA  . PHE   A 1 141 ? -44.64039 -5.53758  9.22243   1.000 38.89274 ? 141 PHE   A CA  1 
ATOM   1111 C  C   . PHE   A 1 141 ? -45.78498 -6.48590  8.88956   1.000 38.79728 ? 141 PHE   A C   1 
ATOM   1112 O  O   . PHE   A 1 141 ? -46.48007 -6.30458  7.88408   1.000 40.07889 ? 141 PHE   A O   1 
ATOM   1113 C  CB  . PHE   A 1 141 ? -43.29470 -6.16367  8.84281   1.000 36.32422 ? 141 PHE   A CB  1 
ATOM   1114 C  CG  . PHE   A 1 141 ? -43.21329 -6.62099  7.40985   1.000 36.18713 ? 141 PHE   A CG  1 
ATOM   1115 C  CD1 . PHE   A 1 141 ? -42.80687 -5.74726  6.41147   1.000 35.21329 ? 141 PHE   A CD1 1 
ATOM   1116 C  CD2 . PHE   A 1 141 ? -43.53214 -7.92712  7.06378   1.000 35.63367 ? 141 PHE   A CD2 1 
ATOM   1117 C  CE1 . PHE   A 1 141 ? -42.72389 -6.16906  5.09108   1.000 36.42088 ? 141 PHE   A CE1 1 
ATOM   1118 C  CE2 . PHE   A 1 141 ? -43.45097 -8.35991  5.74426   1.000 33.41039 ? 141 PHE   A CE2 1 
ATOM   1119 C  CZ  . PHE   A 1 141 ? -43.04736 -7.48091  4.75998   1.000 36.57913 ? 141 PHE   A CZ  1 
ATOM   1120 N  N   . LEU   A 1 142 ? -45.99861 -7.50053  9.72750   1.000 36.26983 ? 142 LEU   A N   1 
ATOM   1121 C  CA  . LEU   A 1 142 ? -47.02067 -8.50004  9.45112   1.000 37.09289 ? 142 LEU   A CA  1 
ATOM   1122 C  C   . LEU   A 1 142 ? -48.42544 -7.92282  9.51302   1.000 42.24540 ? 142 LEU   A C   1 
ATOM   1123 O  O   . LEU   A 1 142 ? -49.33363 -8.46680  8.87501   1.000 38.68516 ? 142 LEU   A O   1 
ATOM   1124 C  CB  . LEU   A 1 142 ? -46.88557 -9.66725  10.43000  1.000 38.94977 ? 142 LEU   A CB  1 
ATOM   1125 C  CG  . LEU   A 1 142 ? -45.62840 -10.52105 10.22811  1.000 36.34786 ? 142 LEU   A CG  1 
ATOM   1126 C  CD1 . LEU   A 1 142 ? -45.41101 -11.45485 11.40915  1.000 37.10332 ? 142 LEU   A CD1 1 
ATOM   1127 C  CD2 . LEU   A 1 142 ? -45.73678 -11.29820 8.93256   1.000 35.11447 ? 142 LEU   A CD2 1 
ATOM   1128 N  N   . ALA   A 1 143 ? -48.62250 -6.82991  10.25415  1.000 41.67662 ? 143 ALA   A N   1 
ATOM   1129 C  CA  . ALA   A 1 143 ? -49.93214 -6.19575  10.32696  1.000 44.54097 ? 143 ALA   A CA  1 
ATOM   1130 C  C   . ALA   A 1 143 ? -50.25488 -5.36806  9.08977   1.000 45.23936 ? 143 ALA   A C   1 
ATOM   1131 O  O   . ALA   A 1 143 ? -51.41870 -5.00030  8.89243   1.000 46.70513 ? 143 ALA   A O   1 
ATOM   1132 C  CB  . ALA   A 1 143 ? -50.02097 -5.31332  11.57405  1.000 45.09757 ? 143 ALA   A CB  1 
ATOM   1133 N  N   . LEU   A 1 144 ? -49.26052 -5.05589  8.26241   1.000 40.83871 ? 144 LEU   A N   1 
ATOM   1134 C  CA  . LEU   A 1 144 ? -49.52051 -4.27726  7.06338   1.000 42.21933 ? 144 LEU   A CA  1 
ATOM   1135 C  C   . LEU   A 1 144 ? -50.34958 -5.09680  6.07488   1.000 40.73563 ? 144 LEU   A C   1 
ATOM   1136 O  O   . LEU   A 1 144 ? -50.29284 -6.32879  6.08144   1.000 40.38117 ? 144 LEU   A O   1 
ATOM   1137 C  CB  . LEU   A 1 144 ? -48.21161 -3.84338  6.41149   1.000 36.47452 ? 144 LEU   A CB  1 
ATOM   1138 C  CG  . LEU   A 1 144 ? -47.35070 -2.86946  7.21636   1.000 40.35506 ? 144 LEU   A CG  1 
ATOM   1139 C  CD1 . LEU   A 1 144 ? -45.97396 -2.75649  6.58830   1.000 41.59629 ? 144 LEU   A CD1 1 
ATOM   1140 C  CD2 . LEU   A 1 144 ? -48.01515 -1.50158  7.31455   1.000 41.29177 ? 144 LEU   A CD2 1 
ATOM   1141 N  N   . PRO   A 1 145 ? -51.14551 -4.43916  5.22858   1.000 45.04201 ? 145 PRO   A N   1 
ATOM   1142 C  CA  . PRO   A 1 145 ? -51.90848 -5.18597  4.22036   1.000 45.42387 ? 145 PRO   A CA  1 
ATOM   1143 C  C   . PRO   A 1 145 ? -50.97694 -5.96711  3.30411   1.000 39.36880 ? 145 PRO   A C   1 
ATOM   1144 O  O   . PRO   A 1 145 ? -49.85273 -5.54629  3.02373   1.000 37.26768 ? 145 PRO   A O   1 
ATOM   1145 C  CB  . PRO   A 1 145 ? -52.66697 -4.09158  3.45482   1.000 45.04597 ? 145 PRO   A CB  1 
ATOM   1146 C  CG  . PRO   A 1 145 ? -52.71038 -2.92027  4.38917   1.000 45.59963 ? 145 PRO   A CG  1 
ATOM   1147 C  CD  . PRO   A 1 145 ? -51.43320 -2.99190  5.18536   1.000 47.99005 ? 145 PRO   A CD  1 
ATOM   1148 N  N   . LEU   A 1 146 ? -51.46104 -7.12556  2.84918   1.000 40.97518 ? 146 LEU   A N   1 
ATOM   1149 C  CA  . LEU   A 1 146 ? -50.65873 -7.99940  1.99693   1.000 41.94565 ? 146 LEU   A CA  1 
ATOM   1150 C  C   . LEU   A 1 146 ? -50.05547 -7.24462  0.81798   1.000 42.77917 ? 146 LEU   A C   1 
ATOM   1151 O  O   . LEU   A 1 146 ? -48.86303 -7.38540  0.52341   1.000 39.40758 ? 146 LEU   A O   1 
ATOM   1152 C  CB  . LEU   A 1 146 ? -51.51009 -9.17611  1.50820   1.000 39.53015 ? 146 LEU   A CB  1 
ATOM   1153 C  CG  . LEU   A 1 146 ? -51.51533 -10.39645 2.42727   1.000 47.34140 ? 146 LEU   A CG  1 
ATOM   1154 C  CD1 . LEU   A 1 146 ? -52.57309 -11.39624 1.99553   1.000 47.10166 ? 146 LEU   A CD1 1 
ATOM   1155 C  CD2 . LEU   A 1 146 ? -50.12805 -11.04562 2.39062   1.000 39.59324 ? 146 LEU   A CD2 1 
ATOM   1156 N  N   . PHE   A 1 147 ? -50.86561 -6.43410  0.13151   1.000 40.29850 ? 147 PHE   A N   1 
ATOM   1157 C  CA  . PHE   A 1 147 ? -50.36283 -5.74087  -1.04946  1.000 44.13702 ? 147 PHE   A CA  1 
ATOM   1158 C  C   . PHE   A 1 147 ? -49.29372 -4.71653  -0.68604  1.000 41.32950 ? 147 PHE   A C   1 
ATOM   1159 O  O   . PHE   A 1 147 ? -48.41699 -4.42920  -1.50605  1.000 43.17477 ? 147 PHE   A O   1 
ATOM   1160 C  CB  . PHE   A 1 147 ? -51.51514 -5.08523  -1.82002  1.000 45.61317 ? 147 PHE   A CB  1 
ATOM   1161 C  CG  . PHE   A 1 147 ? -51.97134 -3.76170  -1.25330  1.000 45.63914 ? 147 PHE   A CG  1 
ATOM   1162 C  CD1 . PHE   A 1 147 ? -52.82063 -3.71199  -0.15740  1.000 47.10810 ? 147 PHE   A CD1 1 
ATOM   1163 C  CD2 . PHE   A 1 147 ? -51.57520 -2.56716  -1.83966  1.000 50.39946 ? 147 PHE   A CD2 1 
ATOM   1164 C  CE1 . PHE   A 1 147 ? -53.25181 -2.49156  0.35340   1.000 50.28646 ? 147 PHE   A CE1 1 
ATOM   1165 C  CE2 . PHE   A 1 147 ? -52.00466 -1.34658  -1.33685  1.000 46.59697 ? 147 PHE   A CE2 1 
ATOM   1166 C  CZ  . PHE   A 1 147 ? -52.84423 -1.31062  -0.23701  1.000 47.88973 ? 147 PHE   A CZ  1 
ATOM   1167 N  N   . ILE   A 1 148 ? -49.33043 -4.17624  0.53353   1.000 41.68707 ? 148 ILE   A N   1 
ATOM   1168 C  CA  . ILE   A 1 148 ? -48.24898 -3.30242  0.98729   1.000 42.04169 ? 148 ILE   A CA  1 
ATOM   1169 C  C   . ILE   A 1 148 ? -46.97752 -4.11473  1.21430   1.000 41.13713 ? 148 ILE   A C   1 
ATOM   1170 O  O   . ILE   A 1 148 ? -45.88418 -3.72523  0.78774   1.000 38.63673 ? 148 ILE   A O   1 
ATOM   1171 C  CB  . ILE   A 1 148 ? -48.66434 -2.54259  2.26145   1.000 39.95856 ? 148 ILE   A CB  1 
ATOM   1172 C  CG1 . ILE   A 1 148 ? -49.82542 -1.58335  1.97739   1.000 46.34596 ? 148 ILE   A CG1 1 
ATOM   1173 C  CG2 . ILE   A 1 148 ? -47.48240 -1.78162  2.83988   1.000 41.52605 ? 148 ILE   A CG2 1 
ATOM   1174 C  CD1 . ILE   A 1 148 ? -49.47047 -0.43041  1.07894   1.000 43.08037 ? 148 ILE   A CD1 1 
ATOM   1175 N  N   . ARG   A 1 149 ? -47.10445 -5.25691  1.89247   1.000 38.79690 ? 149 ARG   A N   1 
ATOM   1176 C  CA  . ARG   A 1 149 ? -45.94481 -6.10552  2.14985   1.000 38.87743 ? 149 ARG   A CA  1 
ATOM   1177 C  C   . ARG   A 1 149 ? -45.29862 -6.57786  0.84978   1.000 41.83710 ? 149 ARG   A C   1 
ATOM   1178 O  O   . ARG   A 1 149 ? -44.06613 -6.60986  0.74165   1.000 40.25980 ? 149 ARG   A O   1 
ATOM   1179 C  CB  . ARG   A 1 149 ? -46.35365 -7.29586  3.01791   1.000 37.97940 ? 149 ARG   A CB  1 
ATOM   1180 C  CG  . ARG   A 1 149 ? -46.52619 -6.96102  4.50149   1.000 36.23392 ? 149 ARG   A CG  1 
ATOM   1181 C  CD  . ARG   A 1 149 ? -46.99220 -8.18151  5.30047   1.000 39.82477 ? 149 ARG   A CD  1 
ATOM   1182 N  NE  . ARG   A 1 149 ? -48.44840 -8.27748  5.37460   1.000 34.55511 ? 149 ARG   A NE  1 
ATOM   1183 C  CZ  . ARG   A 1 149 ? -49.12865 -9.40772  5.51920   1.000 40.06219 ? 149 ARG   A CZ  1 
ATOM   1184 N  NH1 . ARG   A 1 149 ? -48.52020 -10.58685 5.56734   1.000 33.61580 ? 149 ARG   A NH1 1 
ATOM   1185 N  NH2 . ARG   A 1 149 ? -50.45462 -9.35691  5.62351   1.000 36.17771 ? 149 ARG   A NH2 1 
ATOM   1186 N  N   . HIS   A 1 150 ? -46.11283 -6.93725  -0.15112  1.000 40.63212 ? 150 HIS   A N   1 
ATOM   1187 C  CA  . HIS   A 1 150 ? -45.57401 -7.32393  -1.45720  1.000 45.03186 ? 150 HIS   A CA  1 
ATOM   1188 C  C   . HIS   A 1 150 ? -44.70055 -6.22368  -2.04375  1.000 42.04621 ? 150 HIS   A C   1 
ATOM   1189 O  O   . HIS   A 1 150 ? -43.58229 -6.48387  -2.50367  1.000 42.52118 ? 150 HIS   A O   1 
ATOM   1190 C  CB  . HIS   A 1 150 ? -46.70284 -7.65126  -2.43686  1.000 44.20695 ? 150 HIS   A CB  1 
ATOM   1191 C  CG  . HIS   A 1 150 ? -47.21921 -9.04890  -2.33303  1.000 50.79328 ? 150 HIS   A CG  1 
ATOM   1192 N  ND1 . HIS   A 1 150 ? -48.52531 -9.33498  -1.99627  1.000 58.54866 ? 150 HIS   A ND1 1 
ATOM   1193 C  CD2 . HIS   A 1 150 ? -46.61050 -10.24257 -2.52894  1.000 52.23005 ? 150 HIS   A CD2 1 
ATOM   1194 C  CE1 . HIS   A 1 150 ? -48.70019 -10.64463 -1.99235  1.000 58.82839 ? 150 HIS   A CE1 1 
ATOM   1195 N  NE2 . HIS   A 1 150 ? -47.55294 -11.21850 -2.30886  1.000 64.89262 ? 150 HIS   A NE2 1 
ATOM   1196 N  N   . ARG   A 1 151 ? -45.20735 -4.98530  -2.05813  1.000 38.16780 ? 151 ARG   A N   1 
ATOM   1197 C  CA  . ARG   A 1 151 ? -44.44768 -3.88554  -2.64626  1.000 44.19246 ? 151 ARG   A CA  1 
ATOM   1198 C  C   . ARG   A 1 151 ? -43.19494 -3.57584  -1.83815  1.000 42.98024 ? 151 ARG   A C   1 
ATOM   1199 O  O   . ARG   A 1 151 ? -42.14384 -3.27611  -2.41587  1.000 45.31627 ? 151 ARG   A O   1 
ATOM   1200 C  CB  . ARG   A 1 151 ? -45.32296 -2.63484  -2.78055  1.000 44.73882 ? 151 ARG   A CB  1 
ATOM   1201 C  CG  . ARG   A 1 151 ? -46.63938 -2.88901  -3.50339  1.000 54.19292 ? 151 ARG   A CG  1 
ATOM   1202 C  CD  . ARG   A 1 151 ? -47.06981 -1.71091  -4.36398  1.000 60.31678 ? 151 ARG   A CD  1 
ATOM   1203 N  NE  . ARG   A 1 151 ? -47.54041 -0.58297  -3.57046  1.000 67.09674 ? 151 ARG   A NE  1 
ATOM   1204 C  CZ  . ARG   A 1 151 ? -48.49625 0.25384   -3.95479  1.000 69.95581 ? 151 ARG   A CZ  1 
ATOM   1205 N  NH1 . ARG   A 1 151 ? -49.12663 0.10159   -5.10953  1.000 67.17539 ? 151 ARG   A NH1 1 
ATOM   1206 N  NH2 . ARG   A 1 151 ? -48.83136 1.26583   -3.15911  1.000 65.13834 ? 151 ARG   A NH2 1 
ATOM   1207 N  N   . ILE   A 1 152 ? -43.28690 -3.62815  -0.50481  1.000 43.77573 ? 152 ILE   A N   1 
ATOM   1208 C  CA  . ILE   A 1 152 ? -42.10624 -3.41520  0.33271   1.000 40.72430 ? 152 ILE   A CA  1 
ATOM   1209 C  C   . ILE   A 1 152 ? -41.04025 -4.45366  0.00979   1.000 42.70894 ? 152 ILE   A C   1 
ATOM   1210 O  O   . ILE   A 1 152 ? -39.86632 -4.12516  -0.20825  1.000 44.76810 ? 152 ILE   A O   1 
ATOM   1211 C  CB  . ILE   A 1 152 ? -42.48562 -3.46026  1.82420   1.000 40.89115 ? 152 ILE   A CB  1 
ATOM   1212 C  CG1 . ILE   A 1 152 ? -43.31475 -2.23998  2.22276   1.000 42.58328 ? 152 ILE   A CG1 1 
ATOM   1213 C  CG2 . ILE   A 1 152 ? -41.22703 -3.54105  2.69014   1.000 41.34159 ? 152 ILE   A CG2 1 
ATOM   1214 C  CD1 . ILE   A 1 152 ? -43.85496 -2.33639  3.62673   1.000 39.14128 ? 152 ILE   A CD1 1 
ATOM   1215 N  N   . ALA   A 1 153 ? -41.44267 -5.72525  -0.03881  1.000 42.72180 ? 153 ALA   A N   1 
ATOM   1216 C  CA  . ALA   A 1 153 ? -40.48997 -6.80442  -0.27443  1.000 44.00231 ? 153 ALA   A CA  1 
ATOM   1217 C  C   . ALA   A 1 153 ? -39.89591 -6.72908  -1.67445  1.000 47.18705 ? 153 ALA   A C   1 
ATOM   1218 O  O   . ALA   A 1 153 ? -38.69137 -6.94607  -1.85451  1.000 46.36838 ? 153 ALA   A O   1 
ATOM   1219 C  CB  . ALA   A 1 153 ? -41.16758 -8.15538  -0.05378  1.000 41.04774 ? 153 ALA   A CB  1 
ATOM   1220 N  N   . ALA   A 1 154 ? -40.72449 -6.43435  -2.67992  1.000 43.76046 ? 154 ALA   A N   1 
ATOM   1221 C  CA  . ALA   A 1 154 ? -40.21364 -6.32497  -4.04317  1.000 48.90796 ? 154 ALA   A CA  1 
ATOM   1222 C  C   . ALA   A 1 154 ? -39.20797 -5.18493  -4.16424  1.000 47.54576 ? 154 ALA   A C   1 
ATOM   1223 O  O   . ALA   A 1 154 ? -38.18919 -5.31484  -4.85141  1.000 49.49582 ? 154 ALA   A O   1 
ATOM   1224 C  CB  . ALA   A 1 154 ? -41.36889 -6.12928  -5.02579  1.000 47.22272 ? 154 ALA   A CB  1 
ATOM   1225 N  N   . ARG   A 1 155 ? -39.47383 -4.06017  -3.50015  1.000 45.53411 ? 155 ARG   A N   1 
ATOM   1226 C  CA  . ARG   A 1 155 ? -38.53377 -2.94350  -3.54256  1.000 47.43890 ? 155 ARG   A CA  1 
ATOM   1227 C  C   . ARG   A 1 155 ? -37.24893 -3.27345  -2.79423  1.000 51.26806 ? 155 ARG   A C   1 
ATOM   1228 O  O   . ARG   A 1 155 ? -36.15352 -2.91170  -3.23982  1.000 54.17267 ? 155 ARG   A O   1 
ATOM   1229 C  CB  . ARG   A 1 155 ? -39.18367 -1.68903  -2.95950  1.000 45.46193 ? 155 ARG   A CB  1 
ATOM   1230 C  CG  . ARG   A 1 155 ? -38.27065 -0.47443  -2.91058  1.000 48.41158 ? 155 ARG   A CG  1 
ATOM   1231 C  CD  . ARG   A 1 155 ? -37.59864 -0.20842  -4.25565  1.000 56.26789 ? 155 ARG   A CD  1 
ATOM   1232 N  NE  . ARG   A 1 155 ? -38.26432 0.85840   -4.99215  1.000 62.75977 ? 155 ARG   A NE  1 
ATOM   1233 C  CZ  . ARG   A 1 155 ? -38.09919 2.15339   -4.75684  1.000 59.37717 ? 155 ARG   A CZ  1 
ATOM   1234 N  NH1 . ARG   A 1 155 ? -37.27390 2.58731   -3.81816  1.000 67.10825 ? 155 ARG   A NH1 1 
ATOM   1235 N  NH2 . ARG   A 1 155 ? -38.78173 3.03477   -5.47975  1.000 62.08127 ? 155 ARG   A NH2 1 
ATOM   1236 N  N   . MET   A 1 156 ? -37.36551 -3.95230  -1.65040  1.000 48.89001 ? 156 MET   A N   1 
ATOM   1237 C  CA  . MET   A 1 156 ? -36.18478 -4.30059  -0.86835  1.000 50.85264 ? 156 MET   A CA  1 
ATOM   1238 C  C   . MET   A 1 156 ? -35.29226 -5.28387  -1.61261  1.000 53.87043 ? 156 MET   A C   1 
ATOM   1239 O  O   . MET   A 1 156 ? -34.06203 -5.18937  -1.52532  1.000 57.05985 ? 156 MET   A O   1 
ATOM   1240 C  CB  . MET   A 1 156 ? -36.60896 -4.87121  0.48327   1.000 43.71417 ? 156 MET   A CB  1 
ATOM   1241 C  CG  . MET   A 1 156 ? -37.03074 -3.80562  1.48204   1.000 49.70654 ? 156 MET   A CG  1 
ATOM   1242 S  SD  . MET   A 1 156 ? -37.64863 -4.50766  3.01881   1.000 47.60869 ? 156 MET   A SD  1 
ATOM   1243 C  CE  . MET   A 1 156 ? -36.27375 -5.55605  3.46864   1.000 43.76782 ? 156 MET   A CE  1 
ATOM   1244 N  N   . ARG   A 1 157 ? -35.88865 -6.22165  -2.35310  1.000 51.08385 ? 157 ARG   A N   1 
ATOM   1245 C  CA  . ARG   A 1 157 ? -35.09913 -7.14804  -3.15847  1.000 55.94951 ? 157 ARG   A CA  1 
ATOM   1246 C  C   . ARG   A 1 157 ? -34.34816 -6.40606  -4.25819  1.000 60.48019 ? 157 ARG   A C   1 
ATOM   1247 O  O   . ARG   A 1 157 ? -33.15184 -6.63676  -4.47301  1.000 65.45752 ? 157 ARG   A O   1 
ATOM   1248 C  CB  . ARG   A 1 157 ? -36.00327 -8.23371  -3.74947  1.000 51.20664 ? 157 ARG   A CB  1 
ATOM   1249 C  CG  . ARG   A 1 157 ? -36.51635 -9.24155  -2.71651  1.000 52.72196 ? 157 ARG   A CG  1 
ATOM   1250 C  CD  . ARG   A 1 157 ? -37.17974 -10.46817 -3.35743  1.000 57.17690 ? 157 ARG   A CD  1 
ATOM   1251 N  NE  . ARG   A 1 157 ? -38.34220 -10.12332 -4.16975  1.000 59.40283 ? 157 ARG   A NE  1 
ATOM   1252 C  CZ  . ARG   A 1 157 ? -39.58633 -10.05396 -3.71281  1.000 54.89507 ? 157 ARG   A CZ  1 
ATOM   1253 N  NH1 . ARG   A 1 157 ? -39.86474 -10.24734 -2.43353  1.000 50.67770 ? 157 ARG   A NH1 1 
ATOM   1254 N  NH2 . ARG   A 1 157 ? -40.57599 -9.77733  -4.56021  1.000 49.94725 ? 157 ARG   A NH2 1 
ATOM   1255 N  N   . ALA   A 1 158 ? -35.03490 -5.50133  -4.96097  1.000 58.98896 ? 158 ALA   A N   1 
ATOM   1256 C  CA  . ALA   A 1 158 ? -34.37154 -4.70866  -5.99093  1.000 63.90543 ? 158 ALA   A CA  1 
ATOM   1257 C  C   . ALA   A 1 158 ? -33.30769 -3.80257  -5.38587  1.000 65.73042 ? 158 ALA   A C   1 
ATOM   1258 O  O   . ALA   A 1 158 ? -32.23654 -3.61091  -5.97447  1.000 67.69231 ? 158 ALA   A O   1 
ATOM   1259 C  CB  . ALA   A 1 158 ? -35.39918 -3.88534  -6.76725  1.000 62.27015 ? 158 ALA   A CB  1 
ATOM   1260 N  N   . ASP   A 1 159 ? -33.58424 -3.23803  -4.20690  1.000 61.40547 ? 159 ASP   A N   1 
ATOM   1261 C  CA  . ASP   A 1 159 ? -32.59757 -2.39427  -3.53850  1.000 64.06526 ? 159 ASP   A CA  1 
ATOM   1262 C  C   . ASP   A 1 159 ? -31.35641 -3.19612  -3.16594  1.000 69.07542 ? 159 ASP   A C   1 
ATOM   1263 O  O   . ASP   A 1 159 ? -30.23132 -2.68651  -3.23828  1.000 66.60336 ? 159 ASP   A O   1 
ATOM   1264 C  CB  . ASP   A 1 159 ? -33.21259 -1.75078  -2.29546  1.000 63.07570 ? 159 ASP   A CB  1 
ATOM   1265 C  CG  . ASP   A 1 159 ? -34.10623 -0.56779  -2.62784  1.000 63.54924 ? 159 ASP   A CG  1 
ATOM   1266 O  OD1 . ASP   A 1 159 ? -34.08942 -0.10854  -3.79043  1.000 61.33238 ? 159 ASP   A OD1 1 
ATOM   1267 O  OD2 . ASP   A 1 159 ? -34.82851 -0.09960  -1.72147  1.000 61.31670 ? 159 ASP   A OD2 1 
ATOM   1268 N  N   A SER   A 1 160 ? -31.54463 -4.45728  -2.76611  0.545 66.70061 ? 160 SER   A N   1 
ATOM   1269 N  N   B SER   A 1 160 ? -31.53745 -4.45537  -2.76741  0.455 66.62525 ? 160 SER   A N   1 
ATOM   1270 C  CA  A SER   A 1 160 ? -30.41150 -5.31098  -2.42428  0.545 67.31529 ? 160 SER   A CA  1 
ATOM   1271 C  CA  B SER   A 1 160 ? -30.39812 -5.29690  -2.42612  0.455 67.40461 ? 160 SER   A CA  1 
ATOM   1272 C  C   A SER   A 1 160 ? -29.65211 -5.76575  -3.66325  0.545 69.97625 ? 160 SER   A C   1 
ATOM   1273 C  C   B SER   A 1 160 ? -29.66264 -5.81089  -3.65479  0.455 70.07182 ? 160 SER   A C   1 
ATOM   1274 O  O   A SER   A 1 160 ? -28.44383 -6.01714  -3.58741  0.545 72.68368 ? 160 SER   A O   1 
ATOM   1275 O  O   B SER   A 1 160 ? -28.47501 -6.13950  -3.55693  0.455 72.65020 ? 160 SER   A O   1 
ATOM   1276 C  CB  A SER   A 1 160 ? -30.88773 -6.52464  -1.62536  0.545 64.43265 ? 160 SER   A CB  1 
ATOM   1277 C  CB  B SER   A 1 160 ? -30.85288 -6.47361  -1.56188  0.455 65.12421 ? 160 SER   A CB  1 
ATOM   1278 O  OG  A SER   A 1 160 ? -29.84969 -7.03797  -0.81161  0.545 61.67531 ? 160 SER   A OG  1 
ATOM   1279 O  OG  B SER   A 1 160 ? -31.11437 -6.04395  -0.23760  0.455 61.51391 ? 160 SER   A OG  1 
ATOM   1280 N  N   . LYS   A 1 161 ? -30.33561 -5.88313  -4.80503  1.000 70.44417 ? 161 LYS   A N   1 
ATOM   1281 C  CA  . LYS   A 1 161 ? -29.65766 -6.29654  -6.02939  1.000 72.95200 ? 161 LYS   A CA  1 
ATOM   1282 C  C   . LYS   A 1 161 ? -28.67126 -5.23296  -6.49862  1.000 76.25386 ? 161 LYS   A C   1 
ATOM   1283 O  O   . LYS   A 1 161 ? -27.59465 -5.56005  -7.01008  1.000 80.63318 ? 161 LYS   A O   1 
ATOM   1284 C  CB  . LYS   A 1 161 ? -30.68247 -6.60059  -7.12211  1.000 72.19776 ? 161 LYS   A CB  1 
ATOM   1285 N  N   . ALA   A 1 162 ? -29.01515 -3.95983  -6.32610  1.000 78.63639 ? 162 ALA   A N   1 
ATOM   1286 C  CA  . ALA   A 1 162 ? -28.13845 -2.86204  -6.72012  1.000 80.46484 ? 162 ALA   A CA  1 
ATOM   1287 C  C   . ALA   A 1 162 ? -26.90158 -2.79416  -5.82670  1.000 82.41707 ? 162 ALA   A C   1 
ATOM   1288 O  O   . ALA   A 1 162 ? -27.00037 -2.88747  -4.60176  1.000 79.97817 ? 162 ALA   A O   1 
ATOM   1289 C  CB  . ALA   A 1 162 ? -28.89344 -1.54418  -6.68016  1.000 78.69960 ? 162 ALA   A CB  1 
ATOM   1290 N  N   . GLU   A 1 170 ? -22.74092 -12.24482 -4.08810  1.000 80.85856 ? 170 GLU   A N   1 
ATOM   1291 C  CA  . GLU   A 1 170 ? -21.48948 -12.28588 -3.34068  1.000 77.13868 ? 170 GLU   A CA  1 
ATOM   1292 C  C   . GLU   A 1 170 ? -21.75139 -12.49368 -1.85200  1.000 81.84191 ? 170 GLU   A C   1 
ATOM   1293 O  O   . GLU   A 1 170 ? -21.66329 -11.55329 -1.06028  1.000 85.40499 ? 170 GLU   A O   1 
ATOM   1294 C  CB  . GLU   A 1 170 ? -20.69102 -10.99971 -3.56154  1.000 78.21080 ? 170 GLU   A CB  1 
ATOM   1295 N  N   . ILE   A 1 171 ? -22.07231 -13.72923 -1.47627  1.000 72.86176 ? 171 ILE   A N   1 
ATOM   1296 C  CA  . ILE   A 1 171 ? -22.36611 -14.05486 -0.08435  1.000 64.55706 ? 171 ILE   A CA  1 
ATOM   1297 C  C   . ILE   A 1 171 ? -21.06368 -14.12422 0.70291   1.000 63.29392 ? 171 ILE   A C   1 
ATOM   1298 O  O   . ILE   A 1 171 ? -20.13330 -14.85038 0.32946   1.000 62.77306 ? 171 ILE   A O   1 
ATOM   1299 C  CB  . ILE   A 1 171 ? -23.14840 -15.37589 0.01603   1.000 58.88508 ? 171 ILE   A CB  1 
ATOM   1300 C  CG1 . ILE   A 1 171 ? -24.40809 -15.32777 -0.85210  1.000 56.85829 ? 171 ILE   A CG1 1 
ATOM   1301 C  CG2 . ILE   A 1 171 ? -23.50728 -15.67885 1.46413   1.000 54.00468 ? 171 ILE   A CG2 1 
ATOM   1302 C  CD1 . ILE   A 1 171 ? -25.05211 -16.67667 -1.06800  1.000 50.28054 ? 171 ILE   A CD1 1 
ATOM   1303 N  N   . MET   A 1 172 ? -20.99424 -13.35948 1.79245   1.000 59.35712 ? 172 MET   A N   1 
ATOM   1304 C  CA  . MET   A 1 172 ? -19.85438 -13.42935 2.69641   1.000 61.13595 ? 172 MET   A CA  1 
ATOM   1305 C  C   . MET   A 1 172 ? -19.77854 -14.81025 3.33799   1.000 53.70487 ? 172 MET   A C   1 
ATOM   1306 O  O   . MET   A 1 172 ? -20.80043 -15.40511 3.68835   1.000 53.71911 ? 172 MET   A O   1 
ATOM   1307 C  CB  . MET   A 1 172 ? -19.97903 -12.35382 3.77732   1.000 58.23112 ? 172 MET   A CB  1 
ATOM   1308 C  CG  . MET   A 1 172 ? -18.79063 -12.23652 4.71179   1.000 60.45156 ? 172 MET   A CG  1 
ATOM   1309 S  SD  . MET   A 1 172 ? -17.38561 -11.39839 3.96064   1.000 75.75910 ? 172 MET   A SD  1 
ATOM   1310 C  CE  . MET   A 1 172 ? -17.95072 -9.70388  4.07520   1.000 58.35893 ? 172 MET   A CE  1 
ATOM   1311 N  N   . ASP   A 1 173 ? -18.55802 -15.32136 3.48519   1.000 54.24364 ? 173 ASP   A N   1 
ATOM   1312 C  CA  . ASP   A 1 173 ? -18.33268 -16.61246 4.11739   1.000 48.47372 ? 173 ASP   A CA  1 
ATOM   1313 C  C   . ASP   A 1 173 ? -18.32759 -16.46616 5.64102   1.000 48.39257 ? 173 ASP   A C   1 
ATOM   1314 O  O   . ASP   A 1 173 ? -18.35223 -15.35917 6.18845   1.000 50.07013 ? 173 ASP   A O   1 
ATOM   1315 C  CB  . ASP   A 1 173 ? -17.01550 -17.21592 3.63023   1.000 46.79456 ? 173 ASP   A CB  1 
ATOM   1316 C  CG  . ASP   A 1 173 ? -17.02276 -18.73225 3.64284   1.000 46.14985 ? 173 ASP   A CG  1 
ATOM   1317 O  OD1 . ASP   A 1 173 ? -17.98021 -19.33084 4.17911   1.000 43.44512 ? 173 ASP   A OD1 1 
ATOM   1318 O  OD2 . ASP   A 1 173 ? -16.05555 -19.32698 3.12478   1.000 47.18576 ? 173 ASP   A OD2 1 
ATOM   1319 N  N   . VAL   A 1 174 ? -18.27426 -17.61081 6.33115   1.000 44.31827 ? 174 VAL   A N   1 
ATOM   1320 C  CA  . VAL   A 1 174 ? -18.32370 -17.60946 7.79507   1.000 42.71200 ? 174 VAL   A CA  1 
ATOM   1321 C  C   . VAL   A 1 174 ? -17.01347 -17.08374 8.37288   1.000 44.13691 ? 174 VAL   A C   1 
ATOM   1322 O  O   . VAL   A 1 174 ? -15.94701 -17.14019 7.74823   1.000 43.07731 ? 174 VAL   A O   1 
ATOM   1323 C  CB  . VAL   A 1 174 ? -18.62809 -19.01428 8.33942   1.000 41.59152 ? 174 VAL   A CB  1 
ATOM   1324 C  CG1 . VAL   A 1 174 ? -19.91277 -19.56293 7.72562   1.000 41.39596 ? 174 VAL   A CG1 1 
ATOM   1325 C  CG2 . VAL   A 1 174 ? -17.44248 -19.94916 8.08975   1.000 43.85365 ? 174 VAL   A CG2 1 
ATOM   1326 N  N   . ASN   A 1 175 ? -17.10055 -16.57810 9.60668   1.000 45.25958 ? 175 ASN   A N   1 
ATOM   1327 C  CA  . ASN   A 1 175 ? -15.91797 -16.18743 10.36726  1.000 47.89636 ? 175 ASN   A CA  1 
ATOM   1328 C  C   . ASN   A 1 175 ? -15.39650 -17.39324 11.13868  1.000 48.53052 ? 175 ASN   A C   1 
ATOM   1329 O  O   . ASN   A 1 175 ? -16.16273 -18.02343 11.87944  1.000 47.38422 ? 175 ASN   A O   1 
ATOM   1330 C  CB  . ASN   A 1 175 ? -16.24073 -15.05542 11.33629  1.000 47.34234 ? 175 ASN   A CB  1 
ATOM   1331 C  CG  . ASN   A 1 175 ? -15.05109 -14.65834 12.19516  1.000 53.80456 ? 175 ASN   A CG  1 
ATOM   1332 O  OD1 . ASN   A 1 175 ? -14.76260 -15.28380 13.21460  1.000 54.33245 ? 175 ASN   A OD1 1 
ATOM   1333 N  ND2 . ASN   A 1 175 ? -14.35819 -13.60094 11.78497  1.000 52.75394 ? 175 ASN   A ND2 1 
ATOM   1334 N  N   . PRO   A 1 176 ? -14.11660 -17.74280 10.98683  1.000 48.47000 ? 176 PRO   A N   1 
ATOM   1335 C  CA  . PRO   A 1 176 ? -13.60830 -18.95993 11.64491  1.000 49.47371 ? 176 PRO   A CA  1 
ATOM   1336 C  C   . PRO   A 1 176 ? -13.76751 -18.95039 13.15585  1.000 48.94193 ? 176 PRO   A C   1 
ATOM   1337 O  O   . PRO   A 1 176 ? -14.06477 -19.99654 13.74550  1.000 46.69409 ? 176 PRO   A O   1 
ATOM   1338 C  CB  . PRO   A 1 176 ? -12.12909 -18.97971 11.23275  1.000 51.12312 ? 176 PRO   A CB  1 
ATOM   1339 C  CG  . PRO   A 1 176 ? -12.07536 -18.19330 9.96048   1.000 53.89519 ? 176 PRO   A CG  1 
ATOM   1340 C  CD  . PRO   A 1 176 ? -13.10413 -17.10567 10.12838  1.000 49.88503 ? 176 PRO   A CD  1 
ATOM   1341 N  N   . GLN   A 1 177 ? -13.57061 -17.79755 13.80448  1.000 47.45096 ? 177 GLN   A N   1 
ATOM   1342 C  CA  . GLN   A 1 177 ? -13.72956 -17.73842 15.25431  1.000 47.98499 ? 177 GLN   A CA  1 
ATOM   1343 C  C   . GLN   A 1 177 ? -15.19054 -17.91035 15.66212  1.000 46.72464 ? 177 GLN   A C   1 
ATOM   1344 O  O   . GLN   A 1 177 ? -15.48252 -18.53869 16.68669  1.000 48.36326 ? 177 GLN   A O   1 
ATOM   1345 C  CB  . GLN   A 1 177 ? -13.16633 -16.42419 15.79509  1.000 49.83783 ? 177 GLN   A CB  1 
ATOM   1346 N  N   . ALA   A 1 178 ? -16.12314 -17.36883 14.87423  1.000 45.75141 ? 178 ALA   A N   1 
ATOM   1347 C  CA  . ALA   A 1 178 ? -17.54048 -17.55442 15.17841  1.000 48.70997 ? 178 ALA   A CA  1 
ATOM   1348 C  C   . ALA   A 1 178 ? -17.92544 -19.03036 15.12921  1.000 44.81150 ? 178 ALA   A C   1 
ATOM   1349 O  O   . ALA   A 1 178 ? -18.72573 -19.50143 15.94753  1.000 41.79069 ? 178 ALA   A O   1 
ATOM   1350 C  CB  . ALA   A 1 178 ? -18.39845 -16.74179 14.20878  1.000 48.14674 ? 178 ALA   A CB  1 
ATOM   1351 N  N   . VAL   A 1 179 ? -17.35315 -19.77586 14.18087  1.000 45.69169 ? 179 VAL   A N   1 
ATOM   1352 C  CA  . VAL   A 1 179 ? -17.59156 -21.21678 14.10441  1.000 43.39934 ? 179 VAL   A CA  1 
ATOM   1353 C  C   . VAL   A 1 179 ? -17.12720 -21.90305 15.38348  1.000 42.15918 ? 179 VAL   A C   1 
ATOM   1354 O  O   . VAL   A 1 179 ? -17.87269 -22.67367 15.99897  1.000 42.27730 ? 179 VAL   A O   1 
ATOM   1355 C  CB  . VAL   A 1 179 ? -16.89603 -21.80924 12.86559  1.000 45.95274 ? 179 VAL   A CB  1 
ATOM   1356 C  CG1 . VAL   A 1 179 ? -16.90514 -23.34082 12.91845  1.000 38.86735 ? 179 VAL   A CG1 1 
ATOM   1357 C  CG2 . VAL   A 1 179 ? -17.56499 -21.30438 11.59271  1.000 42.28063 ? 179 VAL   A CG2 1 
ATOM   1358 N  N   . VAL   A 1 180 ? -15.88777 -21.63137 15.80456  1.000 42.61668 ? 180 VAL   A N   1 
ATOM   1359 C  CA  . VAL   A 1 180 ? -15.35973 -22.26888 17.00934  1.000 45.27055 ? 180 VAL   A CA  1 
ATOM   1360 C  C   . VAL   A 1 180 ? -16.21567 -21.91552 18.21873  1.000 47.04156 ? 180 VAL   A C   1 
ATOM   1361 O  O   . VAL   A 1 180 ? -16.54950 -22.78395 19.03460  1.000 48.46613 ? 180 VAL   A O   1 
ATOM   1362 C  CB  . VAL   A 1 180 ? -13.88406 -21.87908 17.22747  1.000 49.09642 ? 180 VAL   A CB  1 
ATOM   1363 C  CG1 . VAL   A 1 180 ? -13.39198 -22.37110 18.58628  1.000 49.31277 ? 180 VAL   A CG1 1 
ATOM   1364 C  CG2 . VAL   A 1 180 ? -13.00845 -22.44851 16.11758  1.000 50.89253 ? 180 VAL   A CG2 1 
ATOM   1365 N  N   . ASP   A 1 181 ? -16.58073 -20.63696 18.35613  1.000 45.77725 ? 181 ASP   A N   1 
ATOM   1366 C  CA  . ASP   A 1 181 ? -17.39040 -20.21487 19.49647  1.000 50.01158 ? 181 ASP   A CA  1 
ATOM   1367 C  C   . ASP   A 1 181 ? -18.70288 -20.98569 19.55442  1.000 49.40979 ? 181 ASP   A C   1 
ATOM   1368 O  O   . ASP   A 1 181 ? -19.12209 -21.42960 20.62980  1.000 48.06366 ? 181 ASP   A O   1 
ATOM   1369 C  CB  . ASP   A 1 181 ? -17.65699 -18.70883 19.43030  1.000 50.94758 ? 181 ASP   A CB  1 
ATOM   1370 C  CG  . ASP   A 1 181 ? -18.79859 -18.27284 20.33910  1.000 63.77461 ? 181 ASP   A CG  1 
ATOM   1371 O  OD1 . ASP   A 1 181 ? -18.53631 -17.99100 21.52757  1.000 71.27761 ? 181 ASP   A OD1 1 
ATOM   1372 O  OD2 . ASP   A 1 181 ? -19.95389 -18.19311 19.86577  1.000 68.61738 ? 181 ASP   A OD2 1 
ATOM   1373 N  N   . ALA   A 1 182 ? -19.35840 -21.16627 18.40404  1.000 46.70242 ? 182 ALA   A N   1 
ATOM   1374 C  CA  . ALA   A 1 182 ? -20.62056 -21.90065 18.37973  1.000 47.36785 ? 182 ALA   A CA  1 
ATOM   1375 C  C   . ALA   A 1 182 ? -20.41797 -23.37171 18.72895  1.000 45.21133 ? 182 ALA   A C   1 
ATOM   1376 O  O   . ALA   A 1 182 ? -21.20058 -23.94579 19.49359  1.000 46.95962 ? 182 ALA   A O   1 
ATOM   1377 C  CB  . ALA   A 1 182 ? -21.28294 -21.75924 17.01012  1.000 46.64096 ? 182 ALA   A CB  1 
ATOM   1378 N  N   . MET   A 1 183 ? -19.37200 -23.99891 18.18461  1.000 45.63323 ? 183 MET   A N   1 
ATOM   1379 C  CA  . MET   A 1 183 ? -19.13026 -25.41120 18.45952  1.000 44.78428 ? 183 MET   A CA  1 
ATOM   1380 C  C   . MET   A 1 183 ? -18.67791 -25.64819 19.89219  1.000 48.60036 ? 183 MET   A C   1 
ATOM   1381 O  O   . MET   A 1 183 ? -18.88128 -26.74659 20.42088  1.000 49.27267 ? 183 MET   A O   1 
ATOM   1382 C  CB  . MET   A 1 183 ? -18.10295 -25.96353 17.47032  1.000 40.93475 ? 183 MET   A CB  1 
ATOM   1383 C  CG  . MET   A 1 183 ? -18.48229 -25.70081 16.02329  1.000 37.71870 ? 183 MET   A CG  1 
ATOM   1384 S  SD  . MET   A 1 183 ? -17.69781 -26.77950 14.81526  1.000 41.37181 ? 183 MET   A SD  1 
ATOM   1385 C  CE  . MET   A 1 183 ? -18.20279 -28.40387 15.36336  1.000 37.92151 ? 183 MET   A CE  1 
ATOM   1386 N  N   . GLU   A 1 184 ? -18.08675 -24.64488 20.53667  1.000 46.37883 ? 184 GLU   A N   1 
ATOM   1387 C  CA  . GLU   A 1 184 ? -17.70749 -24.78505 21.93316  1.000 47.26888 ? 184 GLU   A CA  1 
ATOM   1388 C  C   . GLU   A 1 184 ? -18.83253 -24.38931 22.87971  1.000 48.94192 ? 184 GLU   A C   1 
ATOM   1389 O  O   . GLU   A 1 184 ? -18.94768 -24.96988 23.96461  1.000 52.59171 ? 184 GLU   A O   1 
ATOM   1390 C  CB  . GLU   A 1 184 ? -16.43702 -23.97112 22.21437  1.000 50.24674 ? 184 GLU   A CB  1 
ATOM   1391 C  CG  . GLU   A 1 184 ? -15.23176 -24.51665 21.44492  1.000 51.58351 ? 184 GLU   A CG  1 
ATOM   1392 C  CD  . GLU   A 1 184 ? -13.89707 -24.00335 21.94641  1.000 57.63901 ? 184 GLU   A CD  1 
ATOM   1393 O  OE1 . GLU   A 1 184 ? -13.85760 -22.90516 22.53919  1.000 56.78803 ? 184 GLU   A OE1 1 
ATOM   1394 O  OE2 . GLU   A 1 184 ? -12.88269 -24.70908 21.74208  1.000 56.58719 ? 184 GLU   A OE2 1 
ATOM   1395 N  N   . ARG   A 1 185 ? -19.68118 -23.43233 22.49128  1.000 50.33890 ? 185 ARG   A N   1 
ATOM   1396 C  CA  . ARG   A 1 185 ? -20.86052 -23.13464 23.29840  1.000 53.03337 ? 185 ARG   A CA  1 
ATOM   1397 C  C   . ARG   A 1 185 ? -21.74540 -24.36663 23.44280  1.000 52.73370 ? 185 ARG   A C   1 
ATOM   1398 O  O   . ARG   A 1 185 ? -22.27506 -24.63684 24.52718  1.000 50.66665 ? 185 ARG   A O   1 
ATOM   1399 C  CB  . ARG   A 1 185 ? -21.65035 -21.97913 22.68078  1.000 51.04722 ? 185 ARG   A CB  1 
ATOM   1400 C  CG  . ARG   A 1 185 ? -21.19208 -20.59858 23.13629  1.000 57.93732 ? 185 ARG   A CG  1 
ATOM   1401 C  CD  . ARG   A 1 185 ? -22.17228 -19.51468 22.70515  1.000 54.77316 ? 185 ARG   A CD  1 
ATOM   1402 N  NE  . ARG   A 1 185 ? -22.22438 -19.36133 21.25446  1.000 49.18858 ? 185 ARG   A NE  1 
ATOM   1403 C  CZ  . ARG   A 1 185 ? -23.24398 -19.75246 20.50103  1.000 50.33825 ? 185 ARG   A CZ  1 
ATOM   1404 N  NH1 . ARG   A 1 185 ? -24.30679 -20.33727 21.02866  1.000 45.23461 ? 185 ARG   A NH1 1 
ATOM   1405 N  NH2 . ARG   A 1 185 ? -23.19564 -19.55394 19.18543  1.000 46.46119 ? 185 ARG   A NH2 1 
ATOM   1406 N  N   . HIS   A 1 186 ? -21.90326 -25.13233 22.36337  1.000 49.46663 ? 186 HIS   A N   1 
ATOM   1407 C  CA  . HIS   A 1 186 ? -22.72761 -26.33438 22.35182  1.000 48.73790 ? 186 HIS   A CA  1 
ATOM   1408 C  C   . HIS   A 1 186 ? -21.94181 -27.60954 22.63067  1.000 51.02716 ? 186 HIS   A C   1 
ATOM   1409 O  O   . HIS   A 1 186 ? -22.55210 -28.68012 22.72872  1.000 52.33357 ? 186 HIS   A O   1 
ATOM   1410 C  CB  . HIS   A 1 186 ? -23.44657 -26.45739 21.00362  1.000 49.79639 ? 186 HIS   A CB  1 
ATOM   1411 C  CG  . HIS   A 1 186 ? -24.53584 -25.44838 20.81184  1.000 49.21567 ? 186 HIS   A CG  1 
ATOM   1412 N  ND1 . HIS   A 1 186 ? -25.84790 -25.69831 21.15223  1.000 50.40205 ? 186 HIS   A ND1 1 
ATOM   1413 C  CD2 . HIS   A 1 186 ? -24.50351 -24.17709 20.34470  1.000 45.13566 ? 186 HIS   A CD2 1 
ATOM   1414 C  CE1 . HIS   A 1 186 ? -26.57979 -24.62956 20.88967  1.000 50.12418 ? 186 HIS   A CE1 1 
ATOM   1415 N  NE2 . HIS   A 1 186 ? -25.78886 -23.69307 20.39710  1.000 46.30195 ? 186 HIS   A NE2 1 
ATOM   1416 N  N   . HIS   A 1 187 ? -20.61483 -27.51979 22.75357  1.000 51.04771 ? 187 HIS   A N   1 
ATOM   1417 C  CA  . HIS   A 1 187 ? -19.74816 -28.66829 23.03914  1.000 52.28235 ? 187 HIS   A CA  1 
ATOM   1418 C  C   . HIS   A 1 187 ? -19.95467 -29.79748 22.03181  1.000 48.14667 ? 187 HIS   A C   1 
ATOM   1419 O  O   . HIS   A 1 187 ? -20.15049 -30.95883 22.39330  1.000 50.67140 ? 187 HIS   A O   1 
ATOM   1420 C  CB  . HIS   A 1 187 ? -19.95501 -29.17222 24.46864  1.000 54.46008 ? 187 HIS   A CB  1 
ATOM   1421 C  CG  . HIS   A 1 187 ? -19.56530 -28.18097 25.51906  1.000 59.17250 ? 187 HIS   A CG  1 
ATOM   1422 N  ND1 . HIS   A 1 187 ? -20.48027 -27.35963 26.14211  1.000 58.79345 ? 187 HIS   A ND1 1 
ATOM   1423 C  CD2 . HIS   A 1 187 ? -18.35938 -27.87896 26.05772  1.000 56.16454 ? 187 HIS   A CD2 1 
ATOM   1424 C  CE1 . HIS   A 1 187 ? -19.85521 -26.59345 27.01804  1.000 59.20189 ? 187 HIS   A CE1 1 
ATOM   1425 N  NE2 . HIS   A 1 187 ? -18.56800 -26.88957 26.98747  1.000 62.16704 ? 187 HIS   A NE2 1 
ATOM   1426 N  N   . VAL   A 1 188 ? -19.89745 -29.45146 20.74789  1.000 47.33040 ? 188 VAL   A N   1 
ATOM   1427 C  CA  . VAL   A 1 188 ? -20.05234 -30.43661 19.68871  1.000 48.08978 ? 188 VAL   A CA  1 
ATOM   1428 C  C   . VAL   A 1 188 ? -18.78323 -30.47128 18.84944  1.000 47.59120 ? 188 VAL   A C   1 
ATOM   1429 O  O   . VAL   A 1 188 ? -18.00444 -29.51617 18.80688  1.000 46.89393 ? 188 VAL   A O   1 
ATOM   1430 C  CB  . VAL   A 1 188 ? -21.27749 -30.15850 18.79275  1.000 46.39803 ? 188 VAL   A CB  1 
ATOM   1431 C  CG1 . VAL   A 1 188 ? -22.56937 -30.39311 19.56947  1.000 49.42595 ? 188 VAL   A CG1 1 
ATOM   1432 C  CG2 . VAL   A 1 188 ? -21.21312 -28.74695 18.22078  1.000 42.35760 ? 188 VAL   A CG2 1 
ATOM   1433 N  N   . GLN   A 1 189 ? -18.58378 -31.60335 18.17555  1.000 44.88800 ? 189 GLN   A N   1 
ATOM   1434 C  CA  . GLN   A 1 189 ? -17.50258 -31.77258 17.21515  1.000 46.40273 ? 189 GLN   A CA  1 
ATOM   1435 C  C   . GLN   A 1 189 ? -18.00823 -31.79407 15.77918  1.000 44.76995 ? 189 GLN   A C   1 
ATOM   1436 O  O   . GLN   A 1 189 ? -17.21516 -32.02229 14.85903  1.000 43.76782 ? 189 GLN   A O   1 
ATOM   1437 C  CB  . GLN   A 1 189 ? -16.71552 -33.05561 17.51434  1.000 48.32078 ? 189 GLN   A CB  1 
ATOM   1438 C  CG  . GLN   A 1 189 ? -16.23630 -33.20428 18.95863  1.000 50.32028 ? 189 GLN   A CG  1 
ATOM   1439 C  CD  . GLN   A 1 189 ? -15.48796 -31.97934 19.46217  1.000 50.66632 ? 189 GLN   A CD  1 
ATOM   1440 O  OE1 . GLN   A 1 189 ? -15.82734 -31.41100 20.49965  1.000 50.45267 ? 189 GLN   A OE1 1 
ATOM   1441 N  NE2 . GLN   A 1 189 ? -14.46588 -31.56487 18.72157  1.000 47.79837 ? 189 GLN   A NE2 1 
ATOM   1442 N  N   . TRP   A 1 190 ? -19.30969 -31.56817 15.56675  1.000 38.76832 ? 190 TRP   A N   1 
ATOM   1443 C  CA  . TRP   A 1 190 ? -19.91297 -31.59217 14.24210  1.000 41.62985 ? 190 TRP   A CA  1 
ATOM   1444 C  C   . TRP   A 1 190 ? -20.87158 -30.41736 14.11051  1.000 42.06246 ? 190 TRP   A C   1 
ATOM   1445 O  O   . TRP   A 1 190 ? -21.60415 -30.08862 15.04877  1.000 40.66269 ? 190 TRP   A O   1 
ATOM   1446 C  CB  . TRP   A 1 190 ? -20.66263 -32.91837 13.97185  1.000 42.04299 ? 190 TRP   A CB  1 
ATOM   1447 C  CG  . TRP   A 1 190 ? -19.75444 -34.08151 13.65069  1.000 46.23184 ? 190 TRP   A CG  1 
ATOM   1448 C  CD1 . TRP   A 1 190 ? -19.25544 -34.99831 14.53306  1.000 48.48911 ? 190 TRP   A CD1 1 
ATOM   1449 C  CD2 . TRP   A 1 190 ? -19.24830 -34.45392 12.35802  1.000 44.03419 ? 190 TRP   A CD2 1 
ATOM   1450 N  NE1 . TRP   A 1 190 ? -18.46026 -35.90808 13.87399  1.000 47.01426 ? 190 TRP   A NE1 1 
ATOM   1451 C  CE2 . TRP   A 1 190 ? -18.43818 -35.59571 12.53921  1.000 50.40109 ? 190 TRP   A CE2 1 
ATOM   1452 C  CE3 . TRP   A 1 190 ? -19.39049 -33.92340 11.06804  1.000 48.33952 ? 190 TRP   A CE3 1 
ATOM   1453 C  CZ2 . TRP   A 1 190 ? -17.77402 -36.22121 11.47797  1.000 50.43026 ? 190 TRP   A CZ2 1 
ATOM   1454 C  CZ3 . TRP   A 1 190 ? -18.73358 -34.54962 10.01170  1.000 44.57641 ? 190 TRP   A CZ3 1 
ATOM   1455 C  CH2 . TRP   A 1 190 ? -17.93280 -35.68581 10.22665  1.000 47.15207 ? 190 TRP   A CH2 1 
ATOM   1456 N  N   . LEU   A 1 191 ? -20.85579 -29.78612 12.94138  1.000 36.73771 ? 191 LEU   A N   1 
ATOM   1457 C  CA  . LEU   A 1 191 ? -21.72136 -28.65434 12.64960  1.000 38.64707 ? 191 LEU   A CA  1 
ATOM   1458 C  C   . LEU   A 1 191 ? -22.18618 -28.76109 11.20627  1.000 36.60838 ? 191 LEU   A C   1 
ATOM   1459 O  O   . LEU   A 1 191 ? -21.37208 -28.97413 10.30322  1.000 36.19327 ? 191 LEU   A O   1 
ATOM   1460 C  CB  . LEU   A 1 191 ? -20.99443 -27.32314 12.89557  1.000 33.54049 ? 191 LEU   A CB  1 
ATOM   1461 C  CG  . LEU   A 1 191 ? -21.52092 -26.06204 12.20608  1.000 36.10841 ? 191 LEU   A CG  1 
ATOM   1462 C  CD1 . LEU   A 1 191 ? -22.91575 -25.67185 12.71969  1.000 35.45365 ? 191 LEU   A CD1 1 
ATOM   1463 C  CD2 . LEU   A 1 191 ? -20.53513 -24.90927 12.40968  1.000 33.24707 ? 191 LEU   A CD2 1 
ATOM   1464 N  N   . ILE   A 1 192 ? -23.49464 -28.64425 10.99612  1.000 35.16936 ? 192 ILE   A N   1 
ATOM   1465 C  CA  . ILE   A 1 192 ? -24.08480 -28.62798 9.66281   1.000 32.70949 ? 192 ILE   A CA  1 
ATOM   1466 C  C   . ILE   A 1 192 ? -24.80140 -27.29975 9.48547   1.000 35.86709 ? 192 ILE   A C   1 
ATOM   1467 O  O   . ILE   A 1 192 ? -25.57642 -26.88831 10.35598  1.000 34.03418 ? 192 ILE   A O   1 
ATOM   1468 C  CB  . ILE   A 1 192 ? -25.06502 -29.79561 9.44844   1.000 35.30251 ? 192 ILE   A CB  1 
ATOM   1469 C  CG1 . ILE   A 1 192 ? -24.36431 -31.13973 9.65705   1.000 33.80716 ? 192 ILE   A CG1 1 
ATOM   1470 C  CG2 . ILE   A 1 192 ? -25.68732 -29.71120 8.05947   1.000 35.39879 ? 192 ILE   A CG2 1 
ATOM   1471 C  CD1 . ILE   A 1 192 ? -25.31492 -32.32261 9.66917   1.000 33.09640 ? 192 ILE   A CD1 1 
ATOM   1472 N  N   . HIS   A 1 193 ? -24.54518 -26.63121 8.36660   1.000 32.05621 ? 193 HIS   A N   1 
ATOM   1473 C  CA  . HIS   A 1 193 ? -25.20396 -25.36463 8.10023   1.000 32.39500 ? 193 HIS   A CA  1 
ATOM   1474 C  C   . HIS   A 1 193 ? -25.24106 -25.14343 6.59837   1.000 34.79527 ? 193 HIS   A C   1 
ATOM   1475 O  O   . HIS   A 1 193 ? -24.64212 -25.89003 5.81934   1.000 32.74918 ? 193 HIS   A O   1 
ATOM   1476 C  CB  . HIS   A 1 193 ? -24.51119 -24.20330 8.83129   1.000 32.25239 ? 193 HIS   A CB  1 
ATOM   1477 C  CG  . HIS   A 1 193 ? -23.19594 -23.79144 8.23816   1.000 36.46354 ? 193 HIS   A CG  1 
ATOM   1478 N  ND1 . HIS   A 1 193 ? -23.09696 -22.97169 7.13189   1.000 33.06577 ? 193 HIS   A ND1 1 
ATOM   1479 C  CD2 . HIS   A 1 193 ? -21.92375 -24.05600 8.62362   1.000 35.06638 ? 193 HIS   A CD2 1 
ATOM   1480 C  CE1 . HIS   A 1 193 ? -21.82128 -22.76528 6.85198   1.000 36.02415 ? 193 HIS   A CE1 1 
ATOM   1481 N  NE2 . HIS   A 1 193 ? -21.08943 -23.40859 7.74352   1.000 34.92273 ? 193 HIS   A NE2 1 
ATOM   1482 N  N   . GLY   A 1 194 ? -25.98553 -24.11943 6.20315   1.000 33.54313 ? 194 GLY   A N   1 
ATOM   1483 C  CA  . GLY   A 1 194 ? -26.03140 -23.71322 4.81742   1.000 32.35688 ? 194 GLY   A CA  1 
ATOM   1484 C  C   . GLY   A 1 194 ? -25.63103 -22.25938 4.68643   1.000 35.22926 ? 194 GLY   A C   1 
ATOM   1485 O  O   . GLY   A 1 194 ? -24.59445 -21.84095 5.21693   1.000 33.40299 ? 194 GLY   A O   1 
ATOM   1486 N  N   . HIS   A 1 195 ? -26.46346 -21.49706 3.97655   1.000 34.10956 ? 195 HIS   A N   1 
ATOM   1487 C  CA  . HIS   A 1 195 ? -26.34891 -20.05434 3.76592   1.000 40.15577 ? 195 HIS   A CA  1 
ATOM   1488 C  C   . HIS   A 1 195 ? -25.23293 -19.64694 2.80905   1.000 41.31622 ? 195 HIS   A C   1 
ATOM   1489 O  O   . HIS   A 1 195 ? -25.46324 -18.83255 1.91068   1.000 37.66026 ? 195 HIS   A O   1 
ATOM   1490 C  CB  . HIS   A 1 195 ? -26.15296 -19.29880 5.08067   1.000 36.87459 ? 195 HIS   A CB  1 
ATOM   1491 C  CG  . HIS   A 1 195 ? -26.02745 -17.82118 4.88835   1.000 37.91055 ? 195 HIS   A CG  1 
ATOM   1492 N  ND1 . HIS   A 1 195 ? -27.09516 -17.03343 4.52202   1.000 39.15090 ? 195 HIS   A ND1 1 
ATOM   1493 C  CD2 . HIS   A 1 195 ? -24.95872 -16.99254 4.96953   1.000 37.00843 ? 195 HIS   A CD2 1 
ATOM   1494 C  CE1 . HIS   A 1 195 ? -26.69578 -15.77911 4.40151   1.000 45.32382 ? 195 HIS   A CE1 1 
ATOM   1495 N  NE2 . HIS   A 1 195 ? -25.40331 -15.72764 4.66904   1.000 41.93100 ? 195 HIS   A NE2 1 
ATOM   1496 N  N   . THR   A 1 196 ? -24.02457 -20.17937 2.98800   1.000 33.64893 ? 196 THR   A N   1 
ATOM   1497 C  CA  . THR   A 1 196 ? -22.87449 -19.64061 2.26656   1.000 38.34953 ? 196 THR   A CA  1 
ATOM   1498 C  C   . THR   A 1 196 ? -22.73752 -20.15703 0.83620   1.000 41.16565 ? 196 THR   A C   1 
ATOM   1499 O  O   . THR   A 1 196 ? -21.85545 -19.67749 0.11594   1.000 41.09544 ? 196 THR   A O   1 
ATOM   1500 C  CB  . THR   A 1 196 ? -21.59066 -19.94026 3.03608   1.000 41.22608 ? 196 THR   A CB  1 
ATOM   1501 O  OG1 . THR   A 1 196 ? -21.41178 -21.36016 3.12193   1.000 38.20750 ? 196 THR   A OG1 1 
ATOM   1502 C  CG2 . THR   A 1 196 ? -21.65994 -19.33931 4.43912   1.000 39.34607 ? 196 THR   A CG2 1 
ATOM   1503 N  N   . HIS   A 1 197 ? -23.56740 -21.11743 0.41373   1.000 36.77067 ? 197 HIS   A N   1 
ATOM   1504 C  CA  . HIS   A 1 197 ? -23.54451 -21.65806 -0.95049  1.000 37.77534 ? 197 HIS   A CA  1 
ATOM   1505 C  C   . HIS   A 1 197 ? -22.18051 -22.25113 -1.32158  1.000 38.85791 ? 197 HIS   A C   1 
ATOM   1506 O  O   . HIS   A 1 197 ? -21.77784 -22.23298 -2.48962  1.000 37.99091 ? 197 HIS   A O   1 
ATOM   1507 C  CB  . HIS   A 1 197 ? -23.95051 -20.59706 -1.98033  1.000 36.41699 ? 197 HIS   A CB  1 
ATOM   1508 C  CG  . HIS   A 1 197 ? -25.36957 -20.13045 -1.85175  1.000 42.99553 ? 197 HIS   A CG  1 
ATOM   1509 N  ND1 . HIS   A 1 197 ? -26.00758 -19.41456 -2.84260  1.000 49.66709 ? 197 HIS   A ND1 1 
ATOM   1510 C  CD2 . HIS   A 1 197 ? -26.26973 -20.26464 -0.84758  1.000 41.57461 ? 197 HIS   A CD2 1 
ATOM   1511 C  CE1 . HIS   A 1 197 ? -27.24166 -19.13630 -2.45960  1.000 45.99932 ? 197 HIS   A CE1 1 
ATOM   1512 N  NE2 . HIS   A 1 197 ? -27.42655 -19.64123 -1.25283  1.000 44.28653 ? 197 HIS   A NE2 1 
ATOM   1513 N  N   . ARG   A 1 198 ? -21.45094 -22.78826 -0.34470  1.000 36.47474 ? 198 ARG   A N   1 
ATOM   1514 C  CA  . ARG   A 1 198 ? -20.10989 -23.32726 -0.56478  1.000 38.88789 ? 198 ARG   A CA  1 
ATOM   1515 C  C   . ARG   A 1 198 ? -20.06255 -24.75775 -0.03821  1.000 35.77048 ? 198 ARG   A C   1 
ATOM   1516 O  O   . ARG   A 1 198 ? -19.44777 -25.02675 1.00313   1.000 37.40770 ? 198 ARG   A O   1 
ATOM   1517 C  CB  . ARG   A 1 198 ? -19.05907 -22.45589 0.12072   1.000 38.17667 ? 198 ARG   A CB  1 
ATOM   1518 C  CG  . ARG   A 1 198 ? -18.88174 -21.06456 -0.49445  1.000 45.04502 ? 198 ARG   A CG  1 
ATOM   1519 C  CD  . ARG   A 1 198 ? -17.88851 -20.25767 0.32890   1.000 46.72798 ? 198 ARG   A CD  1 
ATOM   1520 N  NE  . ARG   A 1 198 ? -17.52472 -18.98461 -0.28056  1.000 46.54552 ? 198 ARG   A NE  1 
ATOM   1521 C  CZ  . ARG   A 1 198 ? -18.24538 -17.87340 -0.21089  1.000 56.03717 ? 198 ARG   A CZ  1 
ATOM   1522 N  NH1 . ARG   A 1 198 ? -19.40985 -17.83891 0.42124   1.000 52.89344 ? 198 ARG   A NH1 1 
ATOM   1523 N  NH2 . ARG   A 1 198 ? -17.78338 -16.76594 -0.78474  1.000 63.86940 ? 198 ARG   A NH2 1 
ATOM   1524 N  N   . PRO   A 1 199 ? -20.70791 -25.69878 -0.72622  1.000 37.32901 ? 199 PRO   A N   1 
ATOM   1525 C  CA  . PRO   A 1 199 ? -20.77098 -27.06885 -0.20192  1.000 34.53418 ? 199 PRO   A CA  1 
ATOM   1526 C  C   . PRO   A 1 199 ? -19.37190 -27.64649 -0.03076  1.000 37.11644 ? 199 PRO   A C   1 
ATOM   1527 O  O   . PRO   A 1 199 ? -18.54569 -27.60596 -0.94721  1.000 37.98336 ? 199 PRO   A O   1 
ATOM   1528 C  CB  . PRO   A 1 199 ? -21.58885 -27.82299 -1.26018  1.000 34.43809 ? 199 PRO   A CB  1 
ATOM   1529 C  CG  . PRO   A 1 199 ? -21.50023 -26.99608 -2.49622  1.000 35.00063 ? 199 PRO   A CG  1 
ATOM   1530 C  CD  . PRO   A 1 199 ? -21.37613 -25.57095 -2.03228  1.000 36.01741 ? 199 PRO   A CD  1 
ATOM   1531 N  N   . ALA   A 1 200 ? -19.10147 -28.15534 1.16898   1.000 34.37629 ? 200 ALA   A N   1 
ATOM   1532 C  CA  . ALA   A 1 200 ? -17.74316 -28.52147 1.55174   1.000 38.52449 ? 200 ALA   A CA  1 
ATOM   1533 C  C   . ALA   A 1 200 ? -17.77662 -29.23204 2.89760   1.000 40.51336 ? 200 ALA   A C   1 
ATOM   1534 O  O   . ALA   A 1 200 ? -18.77870 -29.20269 3.61903   1.000 35.42180 ? 200 ALA   A O   1 
ATOM   1535 C  CB  . ALA   A 1 200 ? -16.83153 -27.29419 1.62364   1.000 39.01906 ? 200 ALA   A CB  1 
ATOM   1536 N  N   . VAL   A 1 201 ? -16.65420 -29.86978 3.22023   1.000 38.84908 ? 201 VAL   A N   1 
ATOM   1537 C  CA  . VAL   A 1 201 ? -16.37990 -30.42670 4.53928   1.000 38.13177 ? 201 VAL   A CA  1 
ATOM   1538 C  C   . VAL   A 1 201 ? -15.08347 -29.80428 5.03868   1.000 39.42966 ? 201 VAL   A C   1 
ATOM   1539 O  O   . VAL   A 1 201 ? -14.04349 -29.90839 4.37600   1.000 40.24743 ? 201 VAL   A O   1 
ATOM   1540 C  CB  . VAL   A 1 201 ? -16.26970 -31.95959 4.50735   1.000 38.72272 ? 201 VAL   A CB  1 
ATOM   1541 C  CG1 . VAL   A 1 201 ? -15.90826 -32.48953 5.88698   1.000 38.79249 ? 201 VAL   A CG1 1 
ATOM   1542 C  CG2 . VAL   A 1 201 ? -17.57675 -32.57381 4.03693   1.000 39.47326 ? 201 VAL   A CG2 1 
ATOM   1543 N  N   . HIS   A 1 202 ? -15.14238 -29.16460 6.20266   1.000 39.83028 ? 202 HIS   A N   1 
ATOM   1544 C  CA  . HIS   A 1 202 ? -13.98752 -28.51662 6.80906   1.000 41.67581 ? 202 HIS   A CA  1 
ATOM   1545 C  C   . HIS   A 1 202 ? -13.63183 -29.21415 8.11159   1.000 42.49257 ? 202 HIS   A C   1 
ATOM   1546 O  O   . HIS   A 1 202 ? -14.51414 -29.55793 8.90219   1.000 42.78637 ? 202 HIS   A O   1 
ATOM   1547 C  CB  . HIS   A 1 202 ? -14.25996 -27.03668 7.10067   1.000 41.05486 ? 202 HIS   A CB  1 
ATOM   1548 C  CG  . HIS   A 1 202 ? -14.75487 -26.26132 5.92140   1.000 40.49977 ? 202 HIS   A CG  1 
ATOM   1549 N  ND1 . HIS   A 1 202 ? -13.90710 -25.67941 5.00443   1.000 43.01488 ? 202 HIS   A ND1 1 
ATOM   1550 C  CD2 . HIS   A 1 202 ? -16.01102 -25.95796 5.51792   1.000 40.64588 ? 202 HIS   A CD2 1 
ATOM   1551 C  CE1 . HIS   A 1 202 ? -14.61858 -25.05374 4.08443   1.000 44.18010 ? 202 HIS   A CE1 1 
ATOM   1552 N  NE2 . HIS   A 1 202 ? -15.89849 -25.20848 4.37242   1.000 44.90884 ? 202 HIS   A NE2 1 
ATOM   1553 N  N   . GLU   A 1 203 ? -12.34071 -29.41262 8.33495   1.000 43.61952 ? 203 GLU   A N   1 
ATOM   1554 C  CA  . GLU   A 1 203 ? -11.84076 -29.88504 9.61389   1.000 44.11821 ? 203 GLU   A CA  1 
ATOM   1555 C  C   . GLU   A 1 203 ? -11.26477 -28.71625 10.40023  1.000 47.71239 ? 203 GLU   A C   1 
ATOM   1556 O  O   . GLU   A 1 203 ? -10.58253 -27.85203 9.84240   1.000 47.28669 ? 203 GLU   A O   1 
ATOM   1557 C  CB  . GLU   A 1 203 ? -10.77618 -30.96523 9.43010   1.000 43.83987 ? 203 GLU   A CB  1 
ATOM   1558 C  CG  . GLU   A 1 203 ? -10.22987 -31.47990 10.73943  1.000 51.73930 ? 203 GLU   A CG  1 
ATOM   1559 C  CD  . GLU   A 1 203 ? -9.27307  -32.63809 10.55881  1.000 61.22517 ? 203 GLU   A CD  1 
ATOM   1560 O  OE1 . GLU   A 1 203 ? -8.89927  -32.93260 9.40372   1.000 68.08263 ? 203 GLU   A OE1 1 
ATOM   1561 O  OE2 . GLU   A 1 203 ? -8.86620  -33.22678 11.58080  1.000 63.67625 ? 203 GLU   A OE2 1 
ATOM   1562 N  N   . LEU   A 1 204 ? -11.55174 -28.69514 11.69660  1.000 46.31571 ? 204 LEU   A N   1 
ATOM   1563 C  CA  . LEU   A 1 204 ? -11.05161 -27.67379 12.60359  1.000 44.81824 ? 204 LEU   A CA  1 
ATOM   1564 C  C   . LEU   A 1 204 ? -10.82095 -28.33328 13.95736  1.000 48.05558 ? 204 LEU   A C   1 
ATOM   1565 O  O   . LEU   A 1 204 ? -10.88779 -29.55854 14.08912  1.000 46.90758 ? 204 LEU   A O   1 
ATOM   1566 C  CB  . LEU   A 1 204 ? -12.03582 -26.49660 12.67764  1.000 42.34073 ? 204 LEU   A CB  1 
ATOM   1567 C  CG  . LEU   A 1 204 ? -13.42610 -26.81806 13.23584  1.000 43.52123 ? 204 LEU   A CG  1 
ATOM   1568 C  CD1 . LEU   A 1 204 ? -13.90414 -25.71915 14.17978  1.000 43.40449 ? 204 LEU   A CD1 1 
ATOM   1569 C  CD2 . LEU   A 1 204 ? -14.43613 -27.02436 12.10562  1.000 43.49714 ? 204 LEU   A CD2 1 
ATOM   1570 N  N   . GLN   A 1 205 ? -10.54146 -27.52284 14.97104  1.000 49.90989 ? 205 GLN   A N   1 
ATOM   1571 C  CA  . GLN   A 1 205 ? -10.43279 -28.00598 16.33957  1.000 49.20631 ? 205 GLN   A CA  1 
ATOM   1572 C  C   . GLN   A 1 205 ? -11.39254 -27.21673 17.21445  1.000 48.63868 ? 205 GLN   A C   1 
ATOM   1573 O  O   . GLN   A 1 205 ? -11.43144 -25.98430 17.14848  1.000 46.87125 ? 205 GLN   A O   1 
ATOM   1574 C  CB  . GLN   A 1 205 ? -8.99605  -27.89575 16.86394  1.000 57.80774 ? 205 GLN   A CB  1 
ATOM   1575 C  CG  . GLN   A 1 205 ? -8.04308  -28.86552 16.18867  1.000 59.20654 ? 205 GLN   A CG  1 
ATOM   1576 C  CD  . GLN   A 1 205 ? -7.44885  -29.87256 17.15360  1.000 73.00865 ? 205 GLN   A CD  1 
ATOM   1577 O  OE1 . GLN   A 1 205 ? -7.35958  -29.62037 18.35650  1.000 75.04260 ? 205 GLN   A OE1 1 
ATOM   1578 N  NE2 . GLN   A 1 205 ? -7.05345  -31.03147 16.63197  1.000 74.54887 ? 205 GLN   A NE2 1 
ATOM   1579 N  N   . ALA   A 1 206 ? -12.17585 -27.93443 18.01106  1.000 47.44714 ? 206 ALA   A N   1 
ATOM   1580 C  CA  . ALA   A 1 206 ? -13.10908 -27.33591 18.95083  1.000 52.09208 ? 206 ALA   A CA  1 
ATOM   1581 C  C   . ALA   A 1 206 ? -13.14374 -28.21529 20.18765  1.000 52.67535 ? 206 ALA   A C   1 
ATOM   1582 O  O   . ALA   A 1 206 ? -13.14005 -29.44405 20.07497  1.000 55.08593 ? 206 ALA   A O   1 
ATOM   1583 C  CB  . ALA   A 1 206 ? -14.51627 -27.20305 18.35340  1.000 47.42725 ? 206 ALA   A CB  1 
ATOM   1584 N  N   . ASN   A 1 207 ? -13.16907 -27.58363 21.36124  1.000 54.37809 ? 207 ASN   A N   1 
ATOM   1585 C  CA  . ASN   A 1 207 ? -13.16183 -28.30298 22.63392  1.000 53.86719 ? 207 ASN   A CA  1 
ATOM   1586 C  C   . ASN   A 1 207 ? -11.93601 -29.20494 22.75965  1.000 54.97006 ? 207 ASN   A C   1 
ATOM   1587 O  O   . ASN   A 1 207 ? -12.00455 -30.27849 23.36378  1.000 55.98436 ? 207 ASN   A O   1 
ATOM   1588 C  CB  . ASN   A 1 207 ? -14.44687 -29.12184 22.81845  1.000 52.16090 ? 207 ASN   A CB  1 
ATOM   1589 C  CG  . ASN   A 1 207 ? -15.68796 -28.35677 22.41483  1.000 53.20841 ? 207 ASN   A CG  1 
ATOM   1590 O  OD1 . ASN   A 1 207 ? -15.99646 -27.31298 22.98745  1.000 53.39436 ? 207 ASN   A OD1 1 
ATOM   1591 N  ND2 . ASN   A 1 207 ? -16.40961 -28.87212 21.42139  1.000 49.52557 ? 207 ASN   A ND2 1 
ATOM   1592 N  N   . GLY   A 1 208 ? -10.81730 -28.78667 22.16807  1.000 52.73688 ? 208 GLY   A N   1 
ATOM   1593 C  CA  . GLY   A 1 208 ? -9.58542  -29.54210 22.26602  1.000 57.20371 ? 208 GLY   A CA  1 
ATOM   1594 C  C   . GLY   A 1 208 ? -9.53994  -30.82743 21.46906  1.000 63.88440 ? 208 GLY   A C   1 
ATOM   1595 O  O   . GLY   A 1 208 ? -8.67784  -31.67149 21.73346  1.000 62.54645 ? 208 GLY   A O   1 
ATOM   1596 N  N   . GLN   A 1 209 ? -10.42910 -31.00365 20.49899  1.000 59.77652 ? 209 GLN   A N   1 
ATOM   1597 C  CA  . GLN   A 1 209 ? -10.49067 -32.21656 19.69983  1.000 57.58655 ? 209 GLN   A CA  1 
ATOM   1598 C  C   . GLN   A 1 209 ? -10.80106 -31.83992 18.25926  1.000 58.17496 ? 209 GLN   A C   1 
ATOM   1599 O  O   . GLN   A 1 209 ? -11.33335 -30.75724 17.99480  1.000 52.85649 ? 209 GLN   A O   1 
ATOM   1600 C  CB  . GLN   A 1 209 ? -11.55611 -33.18633 20.23156  1.000 61.61724 ? 209 GLN   A CB  1 
ATOM   1601 C  CG  . GLN   A 1 209 ? -11.27640 -33.77772 21.61657  1.000 70.44692 ? 209 GLN   A CG  1 
ATOM   1602 C  CD  . GLN   A 1 209 ? -10.16214 -34.81773 21.62205  1.000 80.81505 ? 209 GLN   A CD  1 
ATOM   1603 O  OE1 . GLN   A 1 209 ? -10.41467 -36.00633 21.81347  1.000 89.86365 ? 209 GLN   A OE1 1 
ATOM   1604 N  NE2 . GLN   A 1 209 ? -8.91947  -34.36831 21.45057  1.000 81.93509 ? 209 GLN   A NE2 1 
ATOM   1605 N  N   . PRO   A 1 210 ? -10.46163 -32.70866 17.30695  1.000 53.63735 ? 210 PRO   A N   1 
ATOM   1606 C  CA  . PRO   A 1 210 ? -10.85214 -32.46079 15.91359  1.000 53.16839 ? 210 PRO   A CA  1 
ATOM   1607 C  C   . PRO   A 1 210 ? -12.35793 -32.30497 15.79504  1.000 48.17485 ? 210 PRO   A C   1 
ATOM   1608 O  O   . PRO   A 1 210 ? -13.12459 -32.98159 16.47969  1.000 50.66718 ? 210 PRO   A O   1 
ATOM   1609 C  CB  . PRO   A 1 210 ? -10.35386 -33.70556 15.16315  1.000 56.35980 ? 210 PRO   A CB  1 
ATOM   1610 C  CG  . PRO   A 1 210 ? -9.38105  -34.37509 16.06950  1.000 55.75782 ? 210 PRO   A CG  1 
ATOM   1611 C  CD  . PRO   A 1 210 ? -9.51491  -33.82511 17.45107  1.000 63.54094 ? 210 PRO   A CD  1 
ATOM   1612 N  N   . ALA   A 1 211 ? -12.77316 -31.38560 14.93123  1.000 45.01813 ? 211 ALA   A N   1 
ATOM   1613 C  CA  . ALA   A 1 211 ? -14.18241 -31.12536 14.68898  1.000 45.69261 ? 211 ALA   A CA  1 
ATOM   1614 C  C   . ALA   A 1 211 ? -14.38375 -30.88496 13.20286  1.000 45.82997 ? 211 ALA   A C   1 
ATOM   1615 O  O   . ALA   A 1 211 ? -13.43234 -30.60116 12.47007  1.000 43.39420 ? 211 ALA   A O   1 
ATOM   1616 C  CB  . ALA   A 1 211 ? -14.69071 -29.92545 15.49749  1.000 46.67278 ? 211 ALA   A CB  1 
ATOM   1617 N  N   . TRP   A 1 212 ? -15.64070 -30.99042 12.76091  1.000 39.99946 ? 212 TRP   A N   1 
ATOM   1618 C  CA  . TRP   A 1 212 ? -15.96257 -30.86281 11.34578  1.000 39.24493 ? 212 TRP   A CA  1 
ATOM   1619 C  C   . TRP   A 1 212 ? -17.15922 -29.94965 11.13481  1.000 40.04645 ? 212 TRP   A C   1 
ATOM   1620 O  O   . TRP   A 1 212 ? -18.13926 -30.00131 11.88510  1.000 38.01936 ? 212 TRP   A O   1 
ATOM   1621 C  CB  . TRP   A 1 212 ? -16.23271 -32.22964 10.70987  1.000 42.95734 ? 212 TRP   A CB  1 
ATOM   1622 C  CG  . TRP   A 1 212 ? -15.00850 -33.10461 10.71056  1.000 45.42749 ? 212 TRP   A CG  1 
ATOM   1623 C  CD1 . TRP   A 1 212 ? -14.08192 -33.22819 9.71655   1.000 47.06141 ? 212 TRP   A CD1 1 
ATOM   1624 C  CD2 . TRP   A 1 212 ? -14.57615 -33.95603 11.77317  1.000 47.04728 ? 212 TRP   A CD2 1 
ATOM   1625 N  NE1 . TRP   A 1 212 ? -13.09583 -34.11780 10.09530  1.000 50.76443 ? 212 TRP   A NE1 1 
ATOM   1626 C  CE2 . TRP   A 1 212 ? -13.38018 -34.57754 11.35447  1.000 48.21648 ? 212 TRP   A CE2 1 
ATOM   1627 C  CE3 . TRP   A 1 212 ? -15.08684 -34.25797 13.03852  1.000 49.38465 ? 212 TRP   A CE3 1 
ATOM   1628 C  CZ2 . TRP   A 1 212 ? -12.69074 -35.48226 12.15539  1.000 53.66238 ? 212 TRP   A CZ2 1 
ATOM   1629 C  CZ3 . TRP   A 1 212 ? -14.39552 -35.15653 13.83579  1.000 51.84664 ? 212 TRP   A CZ3 1 
ATOM   1630 C  CH2 . TRP   A 1 212 ? -13.21262 -35.75902 13.38999  1.000 51.95070 ? 212 TRP   A CH2 1 
ATOM   1631 N  N   . ARG   A 1 213 ? -17.06295 -29.11864 10.09753  1.000 39.12981 ? 213 ARG   A N   1 
ATOM   1632 C  CA  . ARG   A 1 213 ? -18.12878 -28.22463 9.66871   1.000 39.34638 ? 213 ARG   A CA  1 
ATOM   1633 C  C   . ARG   A 1 213 ? -18.54002 -28.62945 8.26106   1.000 42.22367 ? 213 ARG   A C   1 
ATOM   1634 O  O   . ARG   A 1 213 ? -17.72726 -28.56096 7.33247   1.000 38.92294 ? 213 ARG   A O   1 
ATOM   1635 C  CB  . ARG   A 1 213 ? -17.66791 -26.76593 9.69439   1.000 38.02329 ? 213 ARG   A CB  1 
ATOM   1636 C  CG  . ARG   A 1 213 ? -18.72743 -25.77390 9.23116   1.000 38.05396 ? 213 ARG   A CG  1 
ATOM   1637 C  CD  . ARG   A 1 213 ? -18.30087 -24.33610 9.51774   1.000 37.14733 ? 213 ARG   A CD  1 
ATOM   1638 N  NE  . ARG   A 1 213 ? -17.09570 -23.94910 8.79278   1.000 38.92165 ? 213 ARG   A NE  1 
ATOM   1639 C  CZ  . ARG   A 1 213 ? -17.10485 -23.36931 7.59989   1.000 44.30227 ? 213 ARG   A CZ  1 
ATOM   1640 N  NH1 . ARG   A 1 213 ? -18.23898 -23.12167 6.96086   1.000 37.36109 ? 213 ARG   A NH1 1 
ATOM   1641 N  NH2 . ARG   A 1 213 ? -15.95194 -23.01344 7.04130   1.000 39.82606 ? 213 ARG   A NH2 1 
ATOM   1642 N  N   . VAL   A 1 214 ? -19.79153 -29.05465 8.10576   1.000 35.58974 ? 214 VAL   A N   1 
ATOM   1643 C  CA  . VAL   A 1 214 ? -20.31378 -29.54668 6.83615   1.000 34.70821 ? 214 VAL   A CA  1 
ATOM   1644 C  C   . VAL   A 1 214 ? -21.28265 -28.51039 6.29108   1.000 33.89514 ? 214 VAL   A C   1 
ATOM   1645 O  O   . VAL   A 1 214 ? -22.19806 -28.07646 7.00017   1.000 33.90939 ? 214 VAL   A O   1 
ATOM   1646 C  CB  . VAL   A 1 214 ? -21.00018 -30.91435 6.99807   1.000 37.54586 ? 214 VAL   A CB  1 
ATOM   1647 C  CG1 . VAL   A 1 214 ? -21.48615 -31.42274 5.64650   1.000 36.52650 ? 214 VAL   A CG1 1 
ATOM   1648 C  CG2 . VAL   A 1 214 ? -20.04437 -31.91617 7.63859   1.000 37.00013 ? 214 VAL   A CG2 1 
ATOM   1649 N  N   . VAL   A 1 215 ? -21.08466 -28.11626 5.03673   1.000 32.26268 ? 215 VAL   A N   1 
ATOM   1650 C  CA  . VAL   A 1 215 ? -21.81439 -27.00450 4.43527   1.000 31.80096 ? 215 VAL   A CA  1 
ATOM   1651 C  C   . VAL   A 1 215 ? -22.64962 -27.52848 3.27655   1.000 35.93026 ? 215 VAL   A C   1 
ATOM   1652 O  O   . VAL   A 1 215 ? -22.13884 -28.25231 2.41135   1.000 32.25672 ? 215 VAL   A O   1 
ATOM   1653 C  CB  . VAL   A 1 215 ? -20.86623 -25.88676 3.96113   1.000 34.42118 ? 215 VAL   A CB  1 
ATOM   1654 C  CG1 . VAL   A 1 215 ? -21.67377 -24.67905 3.46262   1.000 33.24791 ? 215 VAL   A CG1 1 
ATOM   1655 C  CG2 . VAL   A 1 215 ? -19.92356 -25.47133 5.08898   1.000 35.97346 ? 215 VAL   A CG2 1 
ATOM   1656 N  N   . LEU   A 1 216 ? -23.92626 -27.14810 3.25906   1.000 34.62436 ? 216 LEU   A N   1 
ATOM   1657 C  CA  . LEU   A 1 216 ? -24.85824 -27.52443 2.20911   1.000 33.35215 ? 216 LEU   A CA  1 
ATOM   1658 C  C   . LEU   A 1 216 ? -24.68477 -26.63229 0.98381   1.000 37.10664 ? 216 LEU   A C   1 
ATOM   1659 O  O   . LEU   A 1 216 ? -24.17878 -25.50931 1.06167   1.000 32.38560 ? 216 LEU   A O   1 
ATOM   1660 C  CB  . LEU   A 1 216 ? -26.29947 -27.41475 2.71103   1.000 31.46242 ? 216 LEU   A CB  1 
ATOM   1661 C  CG  . LEU   A 1 216 ? -26.74515 -28.51196 3.67119   1.000 33.42703 ? 216 LEU   A CG  1 
ATOM   1662 C  CD1 . LEU   A 1 216 ? -27.88966 -28.02918 4.56124   1.000 35.53064 ? 216 LEU   A CD1 1 
ATOM   1663 C  CD2 . LEU   A 1 216 ? -27.14022 -29.74331 2.87339   1.000 33.80541 ? 216 LEU   A CD2 1 
ATOM   1664 N  N   . GLY   A 1 217 ? -25.12431 -27.14246 -0.15926  1.000 36.67776 ? 217 GLY   A N   1 
ATOM   1665 C  CA  . GLY   A 1 217 ? -25.13976 -26.37465 -1.38748  1.000 36.37689 ? 217 GLY   A CA  1 
ATOM   1666 C  C   . GLY   A 1 217 ? -26.50452 -25.76556 -1.65331  1.000 38.32028 ? 217 GLY   A C   1 
ATOM   1667 O  O   . GLY   A 1 217 ? -27.52783 -26.26089 -1.18180  1.000 35.82505 ? 217 GLY   A O   1 
ATOM   1668 N  N   . ALA   A 1 218 ? -26.50727 -24.66527 -2.39897  1.000 35.50833 ? 218 ALA   A N   1 
ATOM   1669 C  CA  . ALA   A 1 218 ? -27.75204 -24.09648 -2.88346  1.000 38.99485 ? 218 ALA   A CA  1 
ATOM   1670 C  C   . ALA   A 1 218 ? -28.23843 -24.88776 -4.08965  1.000 38.22960 ? 218 ALA   A C   1 
ATOM   1671 O  O   . ALA   A 1 218 ? -27.44971 -25.51308 -4.80637  1.000 37.38337 ? 218 ALA   A O   1 
ATOM   1672 C  CB  . ALA   A 1 218 ? -27.57152 -22.62082 -3.25973  1.000 39.36644 ? 218 ALA   A CB  1 
ATOM   1673 N  N   . TRP   A 1 219 ? -29.55330 -24.85841 -4.31069  1.000 32.75741 ? 219 TRP   A N   1 
ATOM   1674 C  CA  . TRP   A 1 219 ? -30.16464 -25.58803 -5.42166  1.000 36.44010 ? 219 TRP   A CA  1 
ATOM   1675 C  C   . TRP   A 1 219 ? -30.15907 -24.68401 -6.65221  1.000 40.29610 ? 219 TRP   A C   1 
ATOM   1676 O  O   . TRP   A 1 219 ? -31.17338 -24.11625 -7.05818  1.000 41.68349 ? 219 TRP   A O   1 
ATOM   1677 C  CB  . TRP   A 1 219 ? -31.57220 -26.04568 -5.05688  1.000 34.58178 ? 219 TRP   A CB  1 
ATOM   1678 C  CG  . TRP   A 1 219 ? -31.61077 -27.10551 -3.97600  1.000 32.98596 ? 219 TRP   A CG  1 
ATOM   1679 C  CD1 . TRP   A 1 219 ? -30.87274 -27.13962 -2.82300  1.000 34.47425 ? 219 TRP   A CD1 1 
ATOM   1680 C  CD2 . TRP   A 1 219 ? -32.43204 -28.27918 -3.95994  1.000 33.16798 ? 219 TRP   A CD2 1 
ATOM   1681 N  NE1 . TRP   A 1 219 ? -31.18755 -28.26480 -2.09234  1.000 32.43501 ? 219 TRP   A NE1 1 
ATOM   1682 C  CE2 . TRP   A 1 219 ? -32.14143 -28.97971 -2.76914  1.000 35.34497 ? 219 TRP   A CE2 1 
ATOM   1683 C  CE3 . TRP   A 1 219 ? -33.38479 -28.80667 -4.83689  1.000 36.46801 ? 219 TRP   A CE3 1 
ATOM   1684 C  CZ2 . TRP   A 1 219 ? -32.77030 -30.17822 -2.43596  1.000 33.78190 ? 219 TRP   A CZ2 1 
ATOM   1685 C  CZ3 . TRP   A 1 219 ? -34.01081 -30.00133 -4.50175  1.000 36.51167 ? 219 TRP   A CZ3 1 
ATOM   1686 C  CH2 . TRP   A 1 219 ? -33.70183 -30.67099 -3.31318  1.000 32.32700 ? 219 TRP   A CH2 1 
ATOM   1687 N  N   . HIS   A 1 220 ? -28.98386 -24.56009 -7.26499  1.000 45.00010 ? 220 HIS   A N   1 
ATOM   1688 C  CA  . HIS   A 1 220 ? -28.81590 -23.65392 -8.41036  1.000 49.72461 ? 220 HIS   A CA  1 
ATOM   1689 C  C   . HIS   A 1 220 ? -29.05922 -24.39714 -9.72201  1.000 51.88432 ? 220 HIS   A C   1 
ATOM   1690 O  O   . HIS   A 1 220 ? -30.04048 -24.13284 -10.42220 1.000 60.18228 ? 220 HIS   A O   1 
ATOM   1691 C  CB  . HIS   A 1 220 ? -27.43169 -23.00220 -8.36974  1.000 51.97855 ? 220 HIS   A CB  1 
ATOM   1692 C  CG  . HIS   A 1 220 ? -27.18732 -22.03306 -9.48530  1.000 64.44517 ? 220 HIS   A CG  1 
ATOM   1693 N  ND1 . HIS   A 1 220 ? -26.27851 -22.27288 -10.49462 1.000 61.07606 ? 220 HIS   A ND1 1 
ATOM   1694 C  CD2 . HIS   A 1 220 ? -27.74117 -20.82693 -9.75669  1.000 62.60967 ? 220 HIS   A CD2 1 
ATOM   1695 C  CE1 . HIS   A 1 220 ? -26.27798 -21.25314 -11.33466 1.000 61.95589 ? 220 HIS   A CE1 1 
ATOM   1696 N  NE2 . HIS   A 1 220 ? -27.15711 -20.36301 -10.91051 1.000 61.47881 ? 220 HIS   A NE2 1 
ATOM   1697 N  N   . SER   A 1 221 ? -28.16696 -25.32409 -10.06928 1.000 52.82353 ? 221 SER   A N   1 
ATOM   1698 C  CA  . SER   A 1 221 ? -28.33548 -26.15470 -11.25413 1.000 51.54877 ? 221 SER   A CA  1 
ATOM   1699 C  C   . SER   A 1 221 ? -28.59698 -27.61510 -10.92693 1.000 50.76885 ? 221 SER   A C   1 
ATOM   1700 O  O   . SER   A 1 221 ? -29.10542 -28.34404 -11.78459 1.000 49.70166 ? 221 SER   A O   1 
ATOM   1701 C  CB  . SER   A 1 221 ? -27.09336 -26.06660 -12.15232 1.000 56.45894 ? 221 SER   A CB  1 
ATOM   1702 O  OG  . SER   A 1 221 ? -26.53289 -24.76686 -12.11386 1.000 72.43292 ? 221 SER   A OG  1 
ATOM   1703 N  N   . GLU   A 1 222 ? -28.25836 -28.05135 -9.71682  1.000 44.29353 ? 222 GLU   A N   1 
ATOM   1704 C  CA  . GLU   A 1 222 ? -28.54768 -29.39000 -9.23507  1.000 43.06365 ? 222 GLU   A CA  1 
ATOM   1705 C  C   . GLU   A 1 222 ? -28.93421 -29.27906 -7.76976  1.000 39.11140 ? 222 GLU   A C   1 
ATOM   1706 O  O   . GLU   A 1 222 ? -28.72416 -28.24634 -7.13057  1.000 38.67035 ? 222 GLU   A O   1 
ATOM   1707 C  CB  . GLU   A 1 222 ? -27.34293 -30.33374 -9.41587  1.000 42.55851 ? 222 GLU   A CB  1 
ATOM   1708 C  CG  . GLU   A 1 222 ? -27.09497 -30.74598 -10.86212 1.000 48.88113 ? 222 GLU   A CG  1 
ATOM   1709 C  CD  . GLU   A 1 222 ? -26.43671 -32.11625 -10.99693 1.000 52.82182 ? 222 GLU   A CD  1 
ATOM   1710 O  OE1 . GLU   A 1 222 ? -25.94294 -32.65626 -9.98243  1.000 52.76879 ? 222 GLU   A OE1 1 
ATOM   1711 O  OE2 . GLU   A 1 222 ? -26.41036 -32.65071 -12.12657 1.000 55.19174 ? 222 GLU   A OE2 1 
ATOM   1712 N  N   . GLY   A 1 223 ? -29.50710 -30.35459 -7.24067  1.000 36.27296 ? 223 GLY   A N   1 
ATOM   1713 C  CA  . GLY   A 1 223 ? -29.83322 -30.39979 -5.83445  1.000 35.56041 ? 223 GLY   A CA  1 
ATOM   1714 C  C   . GLY   A 1 223 ? -28.65146 -30.81352 -4.97517  1.000 37.01727 ? 223 GLY   A C   1 
ATOM   1715 O  O   . GLY   A 1 223 ? -27.64915 -31.34049 -5.45264  1.000 35.06335 ? 223 GLY   A O   1 
ATOM   1716 N  N   . SER   A 1 224 ? -28.79090 -30.56461 -3.67447  1.000 32.25609 ? 224 SER   A N   1 
ATOM   1717 C  CA  . SER   A 1 224 ? -27.74558 -30.83137 -2.69742  1.000 33.75862 ? 224 SER   A CA  1 
ATOM   1718 C  C   . SER   A 1 224 ? -28.39488 -31.24046 -1.38377  1.000 34.73671 ? 224 SER   A C   1 
ATOM   1719 O  O   . SER   A 1 224 ? -29.39506 -30.64445 -0.97118  1.000 33.69537 ? 224 SER   A O   1 
ATOM   1720 C  CB  . SER   A 1 224 ? -26.86348 -29.59239 -2.48344  1.000 34.86135 ? 224 SER   A CB  1 
ATOM   1721 O  OG  . SER   A 1 224 ? -25.90142 -29.81673 -1.47453  1.000 43.67307 ? 224 SER   A OG  1 
ATOM   1722 N  N   . MET   A 1 225 ? -27.83064 -32.25909 -0.73584  1.000 32.07795 ? 225 MET   A N   1 
ATOM   1723 C  CA  . MET   A 1 225 ? -28.28092 -32.65957 0.59251   1.000 29.89801 ? 225 MET   A CA  1 
ATOM   1724 C  C   . MET   A 1 225 ? -27.09892 -33.20238 1.37724   1.000 33.11586 ? 225 MET   A C   1 
ATOM   1725 O  O   . MET   A 1 225 ? -26.09990 -33.64479 0.80377   1.000 34.76746 ? 225 MET   A O   1 
ATOM   1726 C  CB  . MET   A 1 225 ? -29.38328 -33.72697 0.53697   1.000 32.42328 ? 225 MET   A CB  1 
ATOM   1727 C  CG  . MET   A 1 225 ? -28.90449 -35.08765 0.03851   1.000 33.67416 ? 225 MET   A CG  1 
ATOM   1728 S  SD  . MET   A 1 225 ? -30.21572 -36.33349 0.01315   1.000 39.43680 ? 225 MET   A SD  1 
ATOM   1729 C  CE  . MET   A 1 225 ? -29.87561 -37.16954 -1.53125  1.000 46.06069 ? 225 MET   A CE  1 
ATOM   1730 N  N   . VAL   A 1 226 ? -27.22851 -33.18159 2.70186   1.000 31.95287 ? 226 VAL   A N   1 
ATOM   1731 C  CA  . VAL   A 1 226 ? -26.33223 -33.92030 3.58714   1.000 32.15012 ? 226 VAL   A CA  1 
ATOM   1732 C  C   . VAL   A 1 226 ? -27.11128 -35.09365 4.16076   1.000 37.13562 ? 226 VAL   A C   1 
ATOM   1733 O  O   . VAL   A 1 226 ? -28.21208 -34.91470 4.69716   1.000 31.73202 ? 226 VAL   A O   1 
ATOM   1734 C  CB  . VAL   A 1 226 ? -25.75881 -33.04020 4.70886   1.000 32.37343 ? 226 VAL   A CB  1 
ATOM   1735 C  CG1 . VAL   A 1 226 ? -25.12832 -33.91469 5.78287   1.000 31.73189 ? 226 VAL   A CG1 1 
ATOM   1736 C  CG2 . VAL   A 1 226 ? -24.71965 -32.08549 4.14767   1.000 30.40737 ? 226 VAL   A CG2 1 
ATOM   1737 N  N   . LYS   A 1 227 ? -26.55374 -36.29208 4.02834   1.000 33.07356 ? 227 LYS   A N   1 
ATOM   1738 C  CA  . LYS   A 1 227 ? -27.15502 -37.50154 4.56847   1.000 32.30192 ? 227 LYS   A CA  1 
ATOM   1739 C  C   . LYS   A 1 227 ? -26.26652 -37.99104 5.70454   1.000 36.65498 ? 227 LYS   A C   1 
ATOM   1740 O  O   . LYS   A 1 227 ? -25.08275 -38.27650 5.49016   1.000 37.75709 ? 227 LYS   A O   1 
ATOM   1741 C  CB  . LYS   A 1 227 ? -27.30619 -38.56284 3.47858   1.000 34.41732 ? 227 LYS   A CB  1 
ATOM   1742 C  CG  . LYS   A 1 227 ? -27.88390 -39.88621 3.94916   1.000 40.14059 ? 227 LYS   A CG  1 
ATOM   1743 C  CD  . LYS   A 1 227 ? -28.73184 -40.52535 2.85356   1.000 44.82651 ? 227 LYS   A CD  1 
ATOM   1744 C  CE  . LYS   A 1 227 ? -28.21651 -41.88016 2.45592   1.000 50.86819 ? 227 LYS   A CE  1 
ATOM   1745 N  NZ  . LYS   A 1 227 ? -29.19207 -42.59108 1.58346   1.000 53.33749 ? 227 LYS   A NZ  1 
ATOM   1746 N  N   . VAL   A 1 228 ? -26.81905 -38.04517 6.91317   1.000 36.04499 ? 228 VAL   A N   1 
ATOM   1747 C  CA  . VAL   A 1 228 ? -26.09746 -38.53983 8.08118   1.000 35.46434 ? 228 VAL   A CA  1 
ATOM   1748 C  C   . VAL   A 1 228 ? -26.60509 -39.94100 8.39274   1.000 39.61397 ? 228 VAL   A C   1 
ATOM   1749 O  O   . VAL   A 1 228 ? -27.81294 -40.14936 8.56334   1.000 33.66289 ? 228 VAL   A O   1 
ATOM   1750 C  CB  . VAL   A 1 228 ? -26.26650 -37.60667 9.29069   1.000 34.58022 ? 228 VAL   A CB  1 
ATOM   1751 C  CG1 . VAL   A 1 228 ? -25.54119 -38.17965 10.50576  1.000 33.38868 ? 228 VAL   A CG1 1 
ATOM   1752 C  CG2 . VAL   A 1 228 ? -25.74054 -36.20198 8.96537   1.000 32.37028 ? 228 VAL   A CG2 1 
ATOM   1753 N  N   . THR   A 1 229 ? -25.68511 -40.90358 8.45886   1.000 35.96416 ? 229 THR   A N   1 
ATOM   1754 C  CA  . THR   A 1 229 ? -26.01358 -42.27608 8.82975   1.000 37.88631 ? 229 THR   A CA  1 
ATOM   1755 C  C   . THR   A 1 229 ? -25.28146 -42.63507 10.12010  1.000 39.79636 ? 229 THR   A C   1 
ATOM   1756 O  O   . THR   A 1 229 ? -24.45457 -41.84763 10.59932  1.000 38.00239 ? 229 THR   A O   1 
ATOM   1757 C  CB  . THR   A 1 229 ? -25.63237 -43.25699 7.71317   1.000 39.79326 ? 229 THR   A CB  1 
ATOM   1758 O  OG1 . THR   A 1 229 ? -24.21120 -43.46365 7.71933   1.000 39.71863 ? 229 THR   A OG1 1 
ATOM   1759 C  CG2 . THR   A 1 229 ? -26.07332 -42.73415 6.35340   1.000 41.44293 ? 229 THR   A CG2 1 
ATOM   1760 N  N   . PRO   A 1 230 ? -25.55274 -43.79484 10.72537  1.000 39.30040 ? 230 PRO   A N   1 
ATOM   1761 C  CA  . PRO   A 1 230 ? -24.71364 -44.22090 11.85658  1.000 45.90306 ? 230 PRO   A CA  1 
ATOM   1762 C  C   . PRO   A 1 230 ? -23.25262 -44.41271 11.47926  1.000 45.47133 ? 230 PRO   A C   1 
ATOM   1763 O  O   . PRO   A 1 230 ? -22.38782 -44.36062 12.36233  1.000 42.46054 ? 230 PRO   A O   1 
ATOM   1764 C  CB  . PRO   A 1 230 ? -25.36017 -45.54173 12.30928  1.000 45.61409 ? 230 PRO   A CB  1 
ATOM   1765 C  CG  . PRO   A 1 230 ? -26.34474 -45.91096 11.23982  1.000 49.76866 ? 230 PRO   A CG  1 
ATOM   1766 C  CD  . PRO   A 1 230 ? -26.75801 -44.63159 10.59583  1.000 41.53761 ? 230 PRO   A CD  1 
ATOM   1767 N  N   . ASP   A 1 231 ? -22.94886 -44.59553 10.19481  1.000 41.74619 ? 231 ASP   A N   1 
ATOM   1768 C  CA  . ASP   A 1 231 ? -21.60954 -44.94543 9.74816   1.000 37.67427 ? 231 ASP   A CA  1 
ATOM   1769 C  C   . ASP   A 1 231 ? -20.81126 -43.77399 9.18989   1.000 42.44565 ? 231 ASP   A C   1 
ATOM   1770 O  O   . ASP   A 1 231 ? -19.57602 -43.80969 9.24293   1.000 40.36780 ? 231 ASP   A O   1 
ATOM   1771 C  CB  . ASP   A 1 231 ? -21.69085 -46.03469 8.67796   1.000 42.92612 ? 231 ASP   A CB  1 
ATOM   1772 C  CG  . ASP   A 1 231 ? -22.18995 -47.35752 9.22953   1.000 49.63978 ? 231 ASP   A CG  1 
ATOM   1773 O  OD1 . ASP   A 1 231 ? -22.11183 -47.55899 10.46004  1.000 46.79037 ? 231 ASP   A OD1 1 
ATOM   1774 O  OD2 . ASP   A 1 231 ? -22.67222 -48.18647 8.43087   1.000 55.89377 ? 231 ASP   A OD2 1 
ATOM   1775 N  N   . ASP   A 1 232 ? -21.45723 -42.74958 8.63485   1.000 36.05257 ? 232 ASP   A N   1 
ATOM   1776 C  CA  . ASP   A 1 232 ? -20.70569 -41.72132 7.92445   1.000 35.73577 ? 232 ASP   A CA  1 
ATOM   1777 C  C   . ASP   A 1 232 ? -21.56721 -40.47476 7.74722   1.000 38.04189 ? 232 ASP   A C   1 
ATOM   1778 O  O   . ASP   A 1 232 ? -22.72965 -40.42575 8.16187   1.000 38.51547 ? 232 ASP   A O   1 
ATOM   1779 C  CB  . ASP   A 1 232 ? -20.20072 -42.25063 6.57336   1.000 36.32588 ? 232 ASP   A CB  1 
ATOM   1780 C  CG  . ASP   A 1 232 ? -21.30985 -42.84173 5.71735   1.000 41.97449 ? 232 ASP   A CG  1 
ATOM   1781 O  OD1 . ASP   A 1 232 ? -22.40079 -42.24543 5.64504   1.000 38.23788 ? 232 ASP   A OD1 1 
ATOM   1782 O  OD2 . ASP   A 1 232 ? -21.09272 -43.90535 5.10445   1.000 42.64811 ? 232 ASP   A OD2 1 
ATOM   1783 N  N   . VAL   A 1 233 ? -20.96707 -39.45261 7.13763   1.000 35.37521 ? 233 VAL   A N   1 
ATOM   1784 C  CA  . VAL   A 1 233 ? -21.65237 -38.22496 6.74214   1.000 36.65463 ? 233 VAL   A CA  1 
ATOM   1785 C  C   . VAL   A 1 233 ? -21.42068 -38.03758 5.24909   1.000 37.66905 ? 233 VAL   A C   1 
ATOM   1786 O  O   . VAL   A 1 233 ? -20.28129 -38.14142 4.77841   1.000 34.15784 ? 233 VAL   A O   1 
ATOM   1787 C  CB  . VAL   A 1 233 ? -21.14793 -37.00362 7.53492   1.000 38.36332 ? 233 VAL   A CB  1 
ATOM   1788 C  CG1 . VAL   A 1 233 ? -21.91865 -35.74675 7.13649   1.000 36.54713 ? 233 VAL   A CG1 1 
ATOM   1789 C  CG2 . VAL   A 1 233 ? -21.27956 -37.25051 9.03098   1.000 41.54068 ? 233 VAL   A CG2 1 
ATOM   1790 N  N   . GLU   A 1 234 ? -22.49766 -37.77380 4.50806   1.000 35.45743 ? 234 GLU   A N   1 
ATOM   1791 C  CA  . GLU   A 1 234 ? -22.47248 -37.78437 3.04922   1.000 31.85937 ? 234 GLU   A CA  1 
ATOM   1792 C  C   . GLU   A 1 234 ? -23.01201 -36.46417 2.51943   1.000 36.77414 ? 234 GLU   A C   1 
ATOM   1793 O  O   . GLU   A 1 234 ? -24.13666 -36.07329 2.84644   1.000 35.94781 ? 234 GLU   A O   1 
ATOM   1794 C  CB  . GLU   A 1 234 ? -23.29326 -38.95534 2.50589   1.000 32.41921 ? 234 GLU   A CB  1 
ATOM   1795 C  CG  . GLU   A 1 234 ? -23.00050 -40.26503 3.22803   1.000 34.04923 ? 234 GLU   A CG  1 
ATOM   1796 C  CD  . GLU   A 1 234 ? -23.87046 -41.40379 2.76822   1.000 39.49993 ? 234 GLU   A CD  1 
ATOM   1797 O  OE1 . GLU   A 1 234 ? -24.68034 -41.20334 1.84320   1.000 38.62315 ? 234 GLU   A OE1 1 
ATOM   1798 O  OE2 . GLU   A 1 234 ? -23.74059 -42.51165 3.32966   1.000 44.67678 ? 234 GLU   A OE2 1 
ATOM   1799 N  N   . LEU   A 1 235 ? -22.20986 -35.78261 1.71089   1.000 32.63456 ? 235 LEU   A N   1 
ATOM   1800 C  CA  . LEU   A 1 235 ? -22.64026 -34.60457 0.97078   1.000 34.77484 ? 235 LEU   A CA  1 
ATOM   1801 C  C   . LEU   A 1 235 ? -22.93621 -35.04995 -0.45578  1.000 35.74370 ? 235 LEU   A C   1 
ATOM   1802 O  O   . LEU   A 1 235 ? -22.04317 -35.54571 -1.15304  1.000 33.30845 ? 235 LEU   A O   1 
ATOM   1803 C  CB  . LEU   A 1 235 ? -21.56071 -33.52226 1.00667   1.000 33.15668 ? 235 LEU   A CB  1 
ATOM   1804 C  CG  . LEU   A 1 235 ? -21.75203 -32.25262 0.17806   1.000 36.43422 ? 235 LEU   A CG  1 
ATOM   1805 C  CD1 . LEU   A 1 235 ? -23.05843 -31.54546 0.54996   1.000 36.72766 ? 235 LEU   A CD1 1 
ATOM   1806 C  CD2 . LEU   A 1 235 ? -20.55373 -31.32485 0.37021   1.000 38.15758 ? 235 LEU   A CD2 1 
ATOM   1807 N  N   . ILE   A 1 236 ? -24.18890 -34.90364 -0.87834  1.000 32.35658 ? 236 ILE   A N   1 
ATOM   1808 C  CA  . ILE   A 1 236 ? -24.68910 -35.57595 -2.07152  1.000 32.45160 ? 236 ILE   A CA  1 
ATOM   1809 C  C   . ILE   A 1 236 ? -25.27084 -34.54038 -3.02029  1.000 40.90189 ? 236 ILE   A C   1 
ATOM   1810 O  O   . ILE   A 1 236 ? -26.10282 -33.71984 -2.61562  1.000 35.95142 ? 236 ILE   A O   1 
ATOM   1811 C  CB  . ILE   A 1 236 ? -25.74775 -36.63841 -1.71406  1.000 33.94979 ? 236 ILE   A CB  1 
ATOM   1812 C  CG1 . ILE   A 1 236 ? -25.13649 -37.69667 -0.78796  1.000 35.14971 ? 236 ILE   A CG1 1 
ATOM   1813 C  CG2 . ILE   A 1 236 ? -26.31709 -37.28289 -2.97768  1.000 32.89976 ? 236 ILE   A CG2 1 
ATOM   1814 C  CD1 . ILE   A 1 236 ? -26.12805 -38.72206 -0.28467  1.000 37.43071 ? 236 ILE   A CD1 1 
ATOM   1815 N  N   . HIS   A 1 237 ? -24.84585 -34.58633 -4.28203  1.000 33.85336 ? 237 HIS   A N   1 
ATOM   1816 C  CA  . HIS   A 1 237 ? -25.37415 -33.70093 -5.30898  1.000 36.83926 ? 237 HIS   A CA  1 
ATOM   1817 C  C   . HIS   A 1 237 ? -26.06120 -34.53138 -6.38210  1.000 36.70621 ? 237 HIS   A C   1 
ATOM   1818 O  O   . HIS   A 1 237 ? -25.55081 -35.58197 -6.78909  1.000 34.73593 ? 237 HIS   A O   1 
ATOM   1819 C  CB  . HIS   A 1 237 ? -24.26802 -32.82736 -5.90417  1.000 35.91893 ? 237 HIS   A CB  1 
ATOM   1820 C  CG  . HIS   A 1 237 ? -23.89252 -31.67783 -5.02260  1.000 41.32230 ? 237 HIS   A CG  1 
ATOM   1821 N  ND1 . HIS   A 1 237 ? -23.23244 -31.84874 -3.82425  1.000 41.29920 ? 237 HIS   A ND1 1 
ATOM   1822 C  CD2 . HIS   A 1 237 ? -24.13465 -30.35017 -5.13300  1.000 41.44013 ? 237 HIS   A CD2 1 
ATOM   1823 C  CE1 . HIS   A 1 237 ? -23.06347 -30.67338 -3.24499  1.000 42.40286 ? 237 HIS   A CE1 1 
ATOM   1824 N  NE2 . HIS   A 1 237 ? -23.59966 -29.74730 -4.01965  1.000 46.10891 ? 237 HIS   A NE2 1 
ATOM   1825 N  N   . PHE   A 1 238 ? -27.22418 -34.06189 -6.82913  1.000 37.03631 ? 238 PHE   A N   1 
ATOM   1826 C  CA  . PHE   A 1 238 ? -28.10945 -34.86262 -7.66323  1.000 37.93059 ? 238 PHE   A CA  1 
ATOM   1827 C  C   . PHE   A 1 238 ? -28.89926 -33.95005 -8.58954  1.000 42.19720 ? 238 PHE   A C   1 
ATOM   1828 O  O   . PHE   A 1 238 ? -29.14748 -32.78701 -8.24933  1.000 40.26888 ? 238 PHE   A O   1 
ATOM   1829 C  CB  . PHE   A 1 238 ? -29.06900 -35.70119 -6.80178  1.000 38.87906 ? 238 PHE   A CB  1 
ATOM   1830 C  CG  . PHE   A 1 238 ? -29.83519 -34.89214 -5.78356  1.000 38.42912 ? 238 PHE   A CG  1 
ATOM   1831 C  CD1 . PHE   A 1 238 ? -29.29378 -34.63934 -4.52793  1.000 35.88029 ? 238 PHE   A CD1 1 
ATOM   1832 C  CD2 . PHE   A 1 238 ? -31.09020 -34.38259 -6.08357  1.000 39.64620 ? 238 PHE   A CD2 1 
ATOM   1833 C  CE1 . PHE   A 1 238 ? -29.98799 -33.88770 -3.58799  1.000 36.39182 ? 238 PHE   A CE1 1 
ATOM   1834 C  CE2 . PHE   A 1 238 ? -31.79863 -33.63062 -5.14638  1.000 37.02005 ? 238 PHE   A CE2 1 
ATOM   1835 C  CZ  . PHE   A 1 238 ? -31.24172 -33.38536 -3.89322  1.000 37.11442 ? 238 PHE   A CZ  1 
ATOM   1836 N  N   . PRO   A 1 239 ? -29.31350 -34.44500 -9.75518  1.000 44.18695 ? 239 PRO   A N   1 
ATOM   1837 C  CA  . PRO   A 1 239 ? -30.08404 -33.60751 -10.68218 1.000 45.49421 ? 239 PRO   A CA  1 
ATOM   1838 C  C   . PRO   A 1 239 ? -31.51299 -33.37622 -10.21049 1.000 45.19013 ? 239 PRO   A C   1 
ATOM   1839 O  O   . PRO   A 1 239 ? -32.09919 -34.19447 -9.49723  1.000 44.87650 ? 239 PRO   A O   1 
ATOM   1840 C  CB  . PRO   A 1 239 ? -30.05604 -34.41075 -11.98792 1.000 47.77296 ? 239 PRO   A CB  1 
ATOM   1841 C  CG  . PRO   A 1 239 ? -29.83492 -35.82392 -11.55432 1.000 52.71191 ? 239 PRO   A CG  1 
ATOM   1842 C  CD  . PRO   A 1 239 ? -28.94270 -35.74180 -10.35287 1.000 46.45516 ? 239 PRO   A CD  1 
ATOM   1843 N  N   . PHE   A 1 240 ? -32.06886 -32.23388 -10.62795 1.000 43.45389 ? 240 PHE   A N   1 
ATOM   1844 C  CA  . PHE   A 1 240 ? -33.44218 -31.87891 -10.27212 1.000 47.54316 ? 240 PHE   A CA  1 
ATOM   1845 C  C   . PHE   A 1 240 ? -34.43187 -32.91781 -10.78581 1.000 47.75939 ? 240 PHE   A C   1 
ATOM   1846 O  O   . PHE   A 1 240 ? -35.21676 -33.48580 -10.01765 1.000 47.33107 ? 240 PHE   A O   1 
ATOM   1847 C  CB  . PHE   A 1 240 ? -33.80321 -30.50457 -10.84141 1.000 44.78141 ? 240 PHE   A CB  1 
ATOM   1848 C  CG  . PHE   A 1 240 ? -33.12855 -29.36076 -10.15836 1.000 45.05279 ? 240 PHE   A CG  1 
ATOM   1849 C  CD1 . PHE   A 1 240 ? -32.72544 -29.46223 -8.83974  1.000 43.86093 ? 240 PHE   A CD1 1 
ATOM   1850 C  CD2 . PHE   A 1 240 ? -32.91246 -28.17053 -10.83420 1.000 43.02522 ? 240 PHE   A CD2 1 
ATOM   1851 C  CE1 . PHE   A 1 240 ? -32.10491 -28.40576 -8.21410  1.000 40.66997 ? 240 PHE   A CE1 1 
ATOM   1852 C  CE2 . PHE   A 1 240 ? -32.28943 -27.11039 -10.21137 1.000 45.90856 ? 240 PHE   A CE2 1 
ATOM   1853 C  CZ  . PHE   A 1 240 ? -31.88425 -27.23121 -8.89695  1.000 43.97708 ? 240 PHE   A CZ  1 
ATOM   1854 N  N   . LEU   A 1 241 ? -34.41987 -33.16133 -12.09212 1.000 48.85297 ? 241 LEU   A N   1 
ATOM   1855 C  CA  . LEU   A 1 241 ? -35.40328 -34.00523 -12.75269 1.000 54.56641 ? 241 LEU   A CA  1 
ATOM   1856 C  C   . LEU   A 1 241 ? -34.82196 -35.37231 -13.08026 1.000 57.76655 ? 241 LEU   A C   1 
ATOM   1857 O  O   . LEU   A 1 241 ? -33.60749 -35.58151 -13.05671 1.000 54.06510 ? 241 LEU   A O   1 
ATOM   1858 C  CB  . LEU   A 1 241 ? -35.91594 -33.34907 -14.03919 1.000 55.58300 ? 241 LEU   A CB  1 
ATOM   1859 C  CG  . LEU   A 1 241 ? -36.54900 -31.95572 -13.96908 1.000 62.06896 ? 241 LEU   A CG  1 
ATOM   1860 C  CD1 . LEU   A 1 241 ? -37.41401 -31.83389 -12.72113 1.000 54.78372 ? 241 LEU   A CD1 1 
ATOM   1861 C  CD2 . LEU   A 1 241 ? -35.51137 -30.83212 -14.04578 1.000 58.20891 ? 241 LEU   A CD2 1 
ATOM   1862 N  N   . GLU   A 1 242 ? -35.71978 -36.30862 -13.39036 1.000 62.40810 ? 242 GLU   A N   1 
ATOM   1863 C  CA  . GLU   A 1 242 ? -35.31505 -37.63326 -13.83998 1.000 69.38963 ? 242 GLU   A CA  1 
ATOM   1864 C  C   . GLU   A 1 242 ? -34.58791 -37.51462 -15.17167 1.000 70.77176 ? 242 GLU   A C   1 
ATOM   1865 O  O   . GLU   A 1 242 ? -35.18839 -37.13353 -16.18142 1.000 72.43174 ? 242 GLU   A O   1 
ATOM   1866 C  CB  . GLU   A 1 242 ? -36.52628 -38.56197 -13.96340 1.000 70.92142 ? 242 GLU   A CB  1 
ATOM   1867 N  N   . GLU   A 1 243 ? -33.29076 -37.81570 -15.17742 1.000 75.61814 ? 243 GLU   A N   1 
ATOM   1868 C  CA  . GLU   A 1 243 ? -32.47121 -37.71259 -16.38358 1.000 78.16479 ? 243 GLU   A CA  1 
ATOM   1869 C  C   . GLU   A 1 243 ? -32.57237 -39.03377 -17.13198 1.000 81.16150 ? 243 GLU   A C   1 
ATOM   1870 O  O   . GLU   A 1 243 ? -31.84423 -39.98962 -16.85597 1.000 80.81639 ? 243 GLU   A O   1 
ATOM   1871 C  CB  . GLU   A 1 243 ? -31.03114 -37.36785 -16.03001 1.000 76.37935 ? 243 GLU   A CB  1 
ATOM   1872 C  CG  . GLU   A 1 243 ? -30.90741 -36.21456 -15.05435 1.000 73.51784 ? 243 GLU   A CG  1 
ATOM   1873 C  CD  . GLU   A 1 243 ? -30.63299 -34.89842 -15.74961 1.000 76.27705 ? 243 GLU   A CD  1 
ATOM   1874 O  OE1 . GLU   A 1 243 ? -31.54844 -34.38722 -16.42756 1.000 77.79966 ? 243 GLU   A OE1 1 
ATOM   1875 O  OE2 . GLU   A 1 243 ? -29.50400 -34.37908 -15.62418 1.000 86.33897 ? 243 GLU   A OE2 1 
ATOM   1876 N  N   . ASN   A 1 244 ? -33.49403 -39.08456 -18.09138 1.000 82.04201 ? 244 ASN   A N   1 
ATOM   1877 C  CA  . ASN   A 1 244 ? -33.72478 -40.29955 -18.86119 1.000 79.90970 ? 244 ASN   A CA  1 
ATOM   1878 C  C   . ASN   A 1 244 ? -32.52171 -40.59420 -19.74561 1.000 80.69456 ? 244 ASN   A C   1 
ATOM   1879 O  O   . ASN   A 1 244 ? -32.18967 -39.80836 -20.63983 1.000 79.44980 ? 244 ASN   A O   1 
ATOM   1880 C  CB  . ASN   A 1 244 ? -34.98559 -40.15679 -19.70523 1.000 77.46781 ? 244 ASN   A CB  1 
ATOM   1881 C  CG  . ASN   A 1 244 ? -36.21724 -39.93018 -18.86391 1.000 79.94038 ? 244 ASN   A CG  1 
ATOM   1882 O  OD1 . ASN   A 1 244 ? -36.78548 -38.83985 -18.86092 1.000 77.83388 ? 244 ASN   A OD1 1 
ATOM   1883 N  ND2 . ASN   A 1 244 ? -36.63059 -40.95716 -18.13020 1.000 81.82757 ? 244 ASN   A ND2 1 
ATOM   1884 N  N   . LEU   A 1 245 ? -31.86860 -41.72353 -19.48924 1.000 75.81050 ? 245 LEU   A N   1 
ATOM   1885 C  CA  . LEU   A 1 245 ? -30.74369 -42.13813 -20.31160 1.000 74.41188 ? 245 LEU   A CA  1 
ATOM   1886 C  C   . LEU   A 1 245 ? -31.20449 -42.41116 -21.73704 1.000 71.87388 ? 245 LEU   A C   1 
ATOM   1887 O  O   . LEU   A 1 245 ? -32.26288 -43.00296 -21.96674 1.000 70.09266 ? 245 LEU   A O   1 
ATOM   1888 C  CB  . LEU   A 1 245 ? -30.08774 -43.38751 -19.72052 1.000 65.47772 ? 245 LEU   A CB  1 
ATOM   1889 C  CG  . LEU   A 1 245 ? -28.90887 -43.98936 -20.48855 1.000 65.49646 ? 245 LEU   A CG  1 
ATOM   1890 N  N   . TYR   A 1 246 ? -30.41181 -41.95036 -22.69880 1.000 66.40988 ? 246 TYR   A N   1 
ATOM   1891 C  CA  . TYR   A 1 246 ? -30.62148 -42.31315 -24.08905 1.000 63.10188 ? 246 TYR   A CA  1 
ATOM   1892 C  C   . TYR   A 1 246 ? -29.25893 -42.41092 -24.75430 1.000 64.69824 ? 246 TYR   A C   1 
ATOM   1893 O  O   . TYR   A 1 246 ? -28.25434 -41.91811 -24.23408 1.000 68.74602 ? 246 TYR   A O   1 
ATOM   1894 C  CB  . TYR   A 1 246 ? -31.53930 -41.31428 -24.80867 1.000 67.59926 ? 246 TYR   A CB  1 
ATOM   1895 C  CG  . TYR   A 1 246 ? -30.91815 -39.96397 -25.07453 1.000 70.26877 ? 246 TYR   A CG  1 
ATOM   1896 C  CD1 . TYR   A 1 246 ? -31.00197 -38.94565 -24.13836 1.000 72.95003 ? 246 TYR   A CD1 1 
ATOM   1897 C  CD2 . TYR   A 1 246 ? -30.26777 -39.70126 -26.27463 1.000 71.73444 ? 246 TYR   A CD2 1 
ATOM   1898 C  CE1 . TYR   A 1 246 ? -30.43926 -37.70781 -24.38086 1.000 80.79783 ? 246 TYR   A CE1 1 
ATOM   1899 C  CE2 . TYR   A 1 246 ? -29.70378 -38.46817 -26.52673 1.000 76.48564 ? 246 TYR   A CE2 1 
ATOM   1900 C  CZ  . TYR   A 1 246 ? -29.79360 -37.47339 -25.57763 1.000 82.77183 ? 246 TYR   A CZ  1 
ATOM   1901 O  OH  . TYR   A 1 246 ? -29.23228 -36.24173 -25.82769 1.000 85.71663 ? 246 TYR   A OH  1 
ATOM   1902 N  N   . PHE   A 1 247 ? -29.23280 -43.06265 -25.90633 1.000 56.09862 ? 247 PHE   A N   1 
ATOM   1903 C  CA  . PHE   A 1 247 ? -27.97751 -43.35652 -26.56958 1.000 58.68559 ? 247 PHE   A CA  1 
ATOM   1904 C  C   . PHE   A 1 247 ? -27.84798 -42.59893 -27.89343 1.000 66.93717 ? 247 PHE   A C   1 
ATOM   1905 O  O   . PHE   A 1 247 ? -26.74743 -42.45251 -28.43926 1.000 65.30123 ? 247 PHE   A O   1 
ATOM   1906 C  CB  . PHE   A 1 247 ? -27.85747 -44.86470 -26.80248 1.000 57.16990 ? 247 PHE   A CB  1 
ATOM   1907 C  CG  . PHE   A 1 247 ? -28.06543 -45.69861 -25.55910 1.000 52.16778 ? 247 PHE   A CG  1 
ATOM   1908 C  CD1 . PHE   A 1 247 ? -27.27651 -45.50786 -24.43472 1.000 55.15336 ? 247 PHE   A CD1 1 
ATOM   1909 C  CD2 . PHE   A 1 247 ? -29.03151 -46.69576 -25.53060 1.000 52.52030 ? 247 PHE   A CD2 1 
ATOM   1910 C  CE1 . PHE   A 1 247 ? -27.45871 -46.28025 -23.29584 1.000 50.15457 ? 247 PHE   A CE1 1 
ATOM   1911 C  CE2 . PHE   A 1 247 ? -29.21826 -47.47617 -24.39543 1.000 50.24675 ? 247 PHE   A CE2 1 
ATOM   1912 C  CZ  . PHE   A 1 247 ? -28.42930 -47.26574 -23.27617 1.000 48.20515 ? 247 PHE   A CZ  1 
ATOM   1913 N  N   . HIS   A 1 250 ? -21.90622 -42.29143 -30.42442 1.000 73.14617 ? 250 HIS   A N   1 
ATOM   1914 C  CA  . HIS   A 1 250 ? -20.46772 -42.19242 -30.64259 1.000 78.49374 ? 250 HIS   A CA  1 
ATOM   1915 C  C   . HIS   A 1 250 ? -19.98078 -43.31836 -31.55704 1.000 80.57738 ? 250 HIS   A C   1 
ATOM   1916 O  O   . HIS   A 1 250 ? -20.76628 -44.17035 -31.97262 1.000 79.29098 ? 250 HIS   A O   1 
ATOM   1917 C  CB  . HIS   A 1 250 ? -19.72078 -42.22797 -29.30831 1.000 78.04173 ? 250 HIS   A CB  1 
ATOM   1918 C  CG  . HIS   A 1 250 ? -20.10226 -41.12462 -28.36865 1.000 85.74831 ? 250 HIS   A CG  1 
ATOM   1919 N  ND1 . HIS   A 1 250 ? -21.13733 -41.23965 -27.46482 1.000 84.63208 ? 250 HIS   A ND1 1 
ATOM   1920 C  CD2 . HIS   A 1 250 ? -19.58294 -39.88679 -28.18858 1.000 85.18534 ? 250 HIS   A CD2 1 
ATOM   1921 C  CE1 . HIS   A 1 250 ? -21.24014 -40.12032 -26.77014 1.000 80.52018 ? 250 HIS   A CE1 1 
ATOM   1922 N  NE2 . HIS   A 1 250 ? -20.30930 -39.28274 -27.19032 1.000 84.18539 ? 250 HIS   A NE2 1 
ATOM   1923 N  N   . HIS   A 1 251 ? -18.68596 -43.31339 -31.87334 1.000 81.70783 ? 251 HIS   A N   1 
ATOM   1924 C  CA  . HIS   A 1 251 ? -18.10182 -44.32193 -32.74861 1.000 85.26751 ? 251 HIS   A CA  1 
ATOM   1925 C  C   . HIS   A 1 251 ? -16.66442 -44.59557 -32.32640 1.000 86.21726 ? 251 HIS   A C   1 
ATOM   1926 O  O   . HIS   A 1 251 ? -16.00751 -43.75832 -31.70224 1.000 86.39454 ? 251 HIS   A O   1 
ATOM   1927 C  CB  . HIS   A 1 251 ? -18.14067 -43.89316 -34.22155 1.000 84.04669 ? 251 HIS   A CB  1 
ATOM   1928 C  CG  . HIS   A 1 251 ? -19.51484 -43.87417 -34.81601 1.000 85.34773 ? 251 HIS   A CG  1 
ATOM   1929 N  ND1 . HIS   A 1 251 ? -20.41463 -42.85680 -34.58079 1.000 82.97061 ? 251 HIS   A ND1 1 
ATOM   1930 C  CD2 . HIS   A 1 251 ? -20.13724 -44.74184 -35.64962 1.000 82.63802 ? 251 HIS   A CD2 1 
ATOM   1931 C  CE1 . HIS   A 1 251 ? -21.53439 -43.10221 -35.23770 1.000 85.22109 ? 251 HIS   A CE1 1 
ATOM   1932 N  NE2 . HIS   A 1 251 ? -21.39189 -44.23926 -35.89527 1.000 78.59637 ? 251 HIS   A NE2 1 
ATOM   1933 N  N   . HIS   A 1 252 ? -16.18283 -45.78390 -32.68158 1.000 89.27547 ? 252 HIS   A N   1 
ATOM   1934 C  CA  . HIS   A 1 252 ? -14.81809 -46.19265 -32.36447 1.000 93.19716 ? 252 HIS   A CA  1 
ATOM   1935 C  C   . HIS   A 1 252 ? -13.86327 -45.85167 -33.50473 1.000 94.33393 ? 252 HIS   A C   1 
ATOM   1936 O  O   . HIS   A 1 252 ? -12.95679 -46.62353 -33.82103 1.000 93.62798 ? 252 HIS   A O   1 
ATOM   1937 C  CB  . HIS   A 1 252 ? -14.76200 -47.69275 -32.06395 1.000 92.45289 ? 252 HIS   A CB  1 
HETATM 1938 C  C13 . A1AVY B 2 .   ? -38.55584 -8.28277  2.89808   1.000 39.43498 ? 301 A1AVY A C13 1 
HETATM 1939 C  C15 . A1AVY B 2 .   ? -38.75067 -10.32946 4.15637   1.000 36.50369 ? 301 A1AVY A C15 1 
HETATM 1940 C  C20 . A1AVY B 2 .   ? -36.26299 -10.39510 1.85910   1.000 38.12863 ? 301 A1AVY A C20 1 
HETATM 1941 C  C21 . A1AVY B 2 .   ? -35.58959 -11.34344 2.63737   1.000 37.25579 ? 301 A1AVY A C21 1 
HETATM 1942 C  C22 . A1AVY B 2 .   ? -34.22514 -11.19050 2.84376   1.000 38.64332 ? 301 A1AVY A C22 1 
HETATM 1943 C  C24 . A1AVY B 2 .   ? -34.23182 -9.15588  1.50045   1.000 41.28462 ? 301 A1AVY A C24 1 
HETATM 1944 C  C26 . A1AVY B 2 .   ? -33.24780 -8.09354  1.02285   1.000 46.21591 ? 301 A1AVY A C26 1 
HETATM 1945 C  C01 . A1AVY B 2 .   ? -39.63620 -8.09257  7.62766   1.000 37.68745 ? 301 A1AVY A C01 1 
HETATM 1946 C  C02 . A1AVY B 2 .   ? -39.43053 -7.47448  6.40164   1.000 37.20968 ? 301 A1AVY A C02 1 
HETATM 1947 C  C04 . A1AVY B 2 .   ? -39.33436 -5.40930  7.33111   1.000 43.63431 ? 301 A1AVY A C04 1 
HETATM 1948 C  C05 . A1AVY B 2 .   ? -39.53112 -5.92830  8.60372   1.000 39.65450 ? 301 A1AVY A C05 1 
HETATM 1949 C  C06 . A1AVY B 2 .   ? -39.68851 -7.30050  8.76884   1.000 38.91992 ? 301 A1AVY A C06 1 
HETATM 1950 C  C07 . A1AVY B 2 .   ? -39.14994 -3.91556  7.11057   1.000 43.87973 ? 301 A1AVY A C07 1 
HETATM 1951 C  C12 . A1AVY B 2 .   ? -39.48710 -7.60217  3.88903   1.000 35.76338 ? 301 A1AVY A C12 1 
HETATM 1952 C  C16 . A1AVY B 2 .   ? -39.70652 -9.64838  5.12452   1.000 37.51067 ? 301 A1AVY A C16 1 
HETATM 1953 C  C23 . A1AVY B 2 .   ? -33.54904 -10.09713 2.26973   1.000 38.17731 ? 301 A1AVY A C23 1 
HETATM 1954 C  C25 . A1AVY B 2 .   ? -35.60752 -9.30103  1.29462   1.000 37.20249 ? 301 A1AVY A C25 1 
HETATM 1955 C  C27 . A1AVY B 2 .   ? -31.91556 -8.46782  1.61290   1.000 47.25900 ? 301 A1AVY A C27 1 
HETATM 1956 C  C29 . A1AVY B 2 .   ? -31.07579 -10.45482 3.01338   1.000 44.77403 ? 301 A1AVY A C29 1 
HETATM 1957 C  C31 . A1AVY B 2 .   ? -29.64411 -9.91719  2.97630   1.000 37.15976 ? 301 A1AVY A C31 1 
HETATM 1958 F  F08 . A1AVY B 2 .   ? -39.88151 -3.50597  6.03780   1.000 51.93683 ? 301 A1AVY A F08 1 
HETATM 1959 F  F09 . A1AVY B 2 .   ? -39.54606 -3.24668  8.22928   1.000 53.33119 ? 301 A1AVY A F09 1 
HETATM 1960 F  F10 . A1AVY B 2 .   ? -37.83316 -3.69310  6.83978   1.000 53.77446 ? 301 A1AVY A F10 1 
HETATM 1961 N  N03 . A1AVY B 2 .   ? -39.28898 -6.17820  6.27185   1.000 39.63741 ? 301 A1AVY A N03 1 
HETATM 1962 N  N11 . A1AVY B 2 .   ? -39.37553 -8.24063  5.18572   1.000 38.10321 ? 301 A1AVY A N11 1 
HETATM 1963 N  N14 . A1AVY B 2 .   ? -38.80037 -9.71744  2.83772   1.000 38.37266 ? 301 A1AVY A N14 1 
HETATM 1964 N  N28 . A1AVY B 2 .   ? -32.11401 -9.71278  2.33488   1.000 43.05151 ? 301 A1AVY A N28 1 
HETATM 1965 O  O18 . A1AVY B 2 .   ? -38.42949 -10.13509 0.27135   1.000 36.32868 ? 301 A1AVY A O18 1 
HETATM 1966 O  O19 . A1AVY B 2 .   ? -38.44910 -11.98169 1.70354   1.000 35.52222 ? 301 A1AVY A O19 1 
HETATM 1967 O  O30 . A1AVY B 2 .   ? -31.33780 -11.46920 3.57461   1.000 41.62620 ? 301 A1AVY A O30 1 
HETATM 1968 S  S17 . A1AVY B 2 .   ? -38.03709 -10.58517 1.60296   1.000 37.55034 ? 301 A1AVY A S17 1 
HETATM 1969 MN MN  . MN    C 3 .   ? -29.15769 -19.17462 0.57043   1.000 65.82335 ? 302 MN    A MN  1 
HETATM 1970 MN MN  . MN    D 3 .   ? -28.82141 -17.66185 3.67526   1.000 99.71674 ? 303 MN    A MN  1 
HETATM 1971 O  O   . HOH   E 4 .   ? -47.42400 -25.03274 14.99489  1.000 54.77964 ? 401 HOH   A O   1 
HETATM 1972 O  O   . HOH   E 4 .   ? -50.41171 -19.75979 0.05930   1.000 40.25608 ? 402 HOH   A O   1 
HETATM 1973 O  O   . HOH   E 4 .   ? -27.43326 -9.17634  13.49439  1.000 52.40273 ? 403 HOH   A O   1 
HETATM 1974 O  O   . HOH   E 4 .   ? -48.26995 -17.84508 11.18942  1.000 40.02046 ? 404 HOH   A O   1 
HETATM 1975 O  O   . HOH   E 4 .   ? -45.21155 -14.55437 -2.25263  1.000 40.80451 ? 405 HOH   A O   1 
HETATM 1976 O  O   . HOH   E 4 .   ? -26.57507 -18.19865 15.93926  1.000 49.49289 ? 406 HOH   A O   1 
HETATM 1977 O  O   . HOH   E 4 .   ? -15.67852 -21.51387 4.34930   1.000 52.29651 ? 407 HOH   A O   1 
HETATM 1978 O  O   . HOH   E 4 .   ? -10.69379 -47.78150 -33.75828 1.000 76.64002 ? 408 HOH   A O   1 
HETATM 1979 O  O   . HOH   E 4 .   ? -38.52403 -22.81729 -7.38561  1.000 33.53394 ? 409 HOH   A O   1 
HETATM 1980 O  O   . HOH   E 4 .   ? -42.08272 -22.87629 -8.87555  1.000 44.88489 ? 410 HOH   A O   1 
HETATM 1981 O  O   . HOH   E 4 .   ? -29.72109 -20.43163 12.18386  1.000 32.07253 ? 411 HOH   A O   1 
HETATM 1982 O  O   . HOH   E 4 .   ? -33.89626 -36.30421 14.44733  1.000 40.65235 ? 412 HOH   A O   1 
HETATM 1983 O  O   . HOH   E 4 .   ? -25.19442 -35.17859 -10.10952 1.000 52.08467 ? 413 HOH   A O   1 
HETATM 1984 O  O   . HOH   E 4 .   ? -42.29659 -17.08954 -1.36961  1.000 40.28302 ? 414 HOH   A O   1 
HETATM 1985 O  O   . HOH   E 4 .   ? -40.58522 -17.43900 -3.29586  1.000 37.28162 ? 415 HOH   A O   1 
HETATM 1986 O  O   . HOH   E 4 .   ? -29.30540 -45.00351 8.11123   1.000 43.16355 ? 416 HOH   A O   1 
HETATM 1987 O  O   . HOH   E 4 .   ? -40.00795 -34.05283 16.98247  1.000 47.34556 ? 417 HOH   A O   1 
HETATM 1988 O  O   . HOH   E 4 .   ? -30.45124 -30.55444 -12.43956 1.000 43.43480 ? 418 HOH   A O   1 
HETATM 1989 O  O   . HOH   E 4 .   ? -17.82257 -25.44043 -2.33163  1.000 38.55585 ? 419 HOH   A O   1 
HETATM 1990 O  O   . HOH   E 4 .   ? -48.20733 -18.30951 2.52914   1.000 36.36805 ? 420 HOH   A O   1 
HETATM 1991 O  O   . HOH   E 4 .   ? -25.26751 -23.08710 1.38079   1.000 42.20761 ? 421 HOH   A O   1 
HETATM 1992 O  O   . HOH   E 4 .   ? -50.61918 -36.01433 2.91023   1.000 45.95080 ? 422 HOH   A O   1 
HETATM 1993 O  O   . HOH   E 4 .   ? -20.75331 -18.14737 17.29512  1.000 56.13451 ? 423 HOH   A O   1 
HETATM 1994 O  O   . HOH   E 4 .   ? -27.20460 -19.09764 11.56622  1.000 36.26546 ? 424 HOH   A O   1 
HETATM 1995 O  O   . HOH   E 4 .   ? -29.34563 -41.18931 -1.14225  1.000 56.83537 ? 425 HOH   A O   1 
HETATM 1996 O  O   . HOH   E 4 .   ? -20.02147 -34.04797 18.71747  1.000 51.03019 ? 426 HOH   A O   1 
HETATM 1997 O  O   . HOH   E 4 .   ? -30.89899 -16.87818 10.91563  1.000 40.53921 ? 427 HOH   A O   1 
HETATM 1998 O  O   . HOH   E 4 .   ? -17.67482 -23.87245 2.80363   1.000 38.81846 ? 428 HOH   A O   1 
HETATM 1999 O  O   . HOH   E 4 .   ? -29.25899 -28.18386 0.18252   1.000 33.53444 ? 429 HOH   A O   1 
HETATM 2000 O  O   . HOH   E 4 .   ? -39.13658 -13.61923 5.60698   1.000 31.82614 ? 430 HOH   A O   1 
HETATM 2001 O  O   . HOH   E 4 .   ? -17.71765 -13.62021 8.19274   1.000 50.56309 ? 431 HOH   A O   1 
HETATM 2002 O  O   . HOH   E 4 .   ? -18.91962 -21.89373 4.27968   1.000 38.35893 ? 432 HOH   A O   1 
HETATM 2003 O  O   . HOH   E 4 .   ? -35.39238 -20.79799 13.27330  1.000 35.44719 ? 433 HOH   A O   1 
HETATM 2004 O  O   . HOH   E 4 .   ? -32.06326 -19.09151 11.88296  1.000 39.93874 ? 434 HOH   A O   1 
HETATM 2005 O  O   . HOH   E 4 .   ? -48.95166 -20.25070 4.70776   1.000 42.90836 ? 435 HOH   A O   1 
HETATM 2006 O  O   . HOH   E 4 .   ? -50.56513 -33.52125 1.59192   1.000 43.93042 ? 436 HOH   A O   1 
HETATM 2007 O  O   . HOH   E 4 .   ? -42.89468 -33.01052 11.48957  1.000 36.17369 ? 437 HOH   A O   1 
HETATM 2008 O  O   . HOH   E 4 .   ? -48.36113 -39.56738 2.47666   1.000 45.96719 ? 438 HOH   A O   1 
HETATM 2009 O  O   . HOH   E 4 .   ? -53.88066 -19.80595 -2.19246  1.000 48.36198 ? 439 HOH   A O   1 
HETATM 2010 O  O   . HOH   E 4 .   ? -43.91415 -21.83601 -11.73309 1.000 45.96868 ? 440 HOH   A O   1 
HETATM 2011 O  O   . HOH   E 4 .   ? -45.14441 -14.88915 2.10721   1.000 37.10766 ? 441 HOH   A O   1 
HETATM 2012 O  O   . HOH   E 4 .   ? -31.06180 -27.96829 21.05715  1.000 51.70814 ? 442 HOH   A O   1 
HETATM 2013 O  O   . HOH   E 4 .   ? -13.53162 -35.60944 17.37789  1.000 52.21579 ? 443 HOH   A O   1 
HETATM 2014 O  O   . HOH   E 4 .   ? -10.00205 -26.56137 20.66295  1.000 58.47815 ? 444 HOH   A O   1 
HETATM 2015 O  O   . HOH   E 4 .   ? -49.80503 -30.19363 11.19780  1.000 46.01447 ? 445 HOH   A O   1 
HETATM 2016 O  O   . HOH   E 4 .   ? -34.63073 -34.05898 -7.17257  1.000 43.52920 ? 446 HOH   A O   1 
HETATM 2017 O  O   . HOH   E 4 .   ? -48.18950 -30.44745 -3.86398  1.000 46.59565 ? 447 HOH   A O   1 
HETATM 2018 O  O   . HOH   E 4 .   ? -33.38286 -16.24444 10.25240  1.000 45.18729 ? 448 HOH   A O   1 
HETATM 2019 O  O   . HOH   E 4 .   ? -33.05568 -41.35156 2.51093   1.000 52.30249 ? 449 HOH   A O   1 
HETATM 2020 O  O   . HOH   E 4 .   ? -44.45705 -35.37402 -1.26067  1.000 35.54805 ? 450 HOH   A O   1 
HETATM 2021 O  O   . HOH   E 4 .   ? -53.56796 -5.92392  7.22720   1.000 48.20550 ? 451 HOH   A O   1 
HETATM 2022 O  O   . HOH   E 4 .   ? -44.81810 -15.09979 -7.26280  1.000 56.53730 ? 452 HOH   A O   1 
HETATM 2023 O  O   . HOH   E 4 .   ? -36.55447 -36.85939 14.71829  1.000 42.74317 ? 453 HOH   A O   1 
HETATM 2024 O  O   . HOH   E 4 .   ? -32.14948 -32.24585 -13.60454 1.000 53.38329 ? 454 HOH   A O   1 
HETATM 2025 O  O   . HOH   E 4 .   ? -30.44381 -40.29873 15.95652  1.000 48.69688 ? 455 HOH   A O   1 
HETATM 2026 O  O   . HOH   E 4 .   ? -24.00561 -23.74271 -3.60959  1.000 38.76163 ? 456 HOH   A O   1 
HETATM 2027 O  O   . HOH   E 4 .   ? -36.53108 -23.15914 -13.38689 1.000 49.48696 ? 457 HOH   A O   1 
HETATM 2028 O  O   . HOH   E 4 .   ? -43.58035 -25.60152 15.29751  1.000 39.50930 ? 458 HOH   A O   1 
HETATM 2029 O  O   . HOH   E 4 .   ? -46.44768 -15.22212 9.28801   1.000 44.71260 ? 459 HOH   A O   1 
HETATM 2030 O  O   . HOH   E 4 .   ? -43.78365 -34.25557 -3.59319  1.000 43.20077 ? 460 HOH   A O   1 
HETATM 2031 O  O   . HOH   E 4 .   ? -42.66836 -17.19709 -5.59477  1.000 38.58140 ? 461 HOH   A O   1 
HETATM 2032 O  O   . HOH   E 4 .   ? -31.059   -38.383   -8.339    1.000 46.00216 ? 462 HOH   A O   1 
HETATM 2033 O  O   . HOH   E 4 .   ? -32.22291 -12.03587 7.80583   1.000 45.24978 ? 463 HOH   A O   1 
HETATM 2034 O  O   . HOH   E 4 .   ? -41.86804 -15.19695 -6.47079  1.000 54.96517 ? 464 HOH   A O   1 
HETATM 2035 O  O   . HOH   E 4 .   ? -14.17502 -23.76864 9.73147   1.000 48.93723 ? 465 HOH   A O   1 
HETATM 2036 O  O   . HOH   E 4 .   ? -29.43454 -15.72289 0.71967   1.000 44.77673 ? 466 HOH   A O   1 
HETATM 2037 O  O   . HOH   E 4 .   ? -12.96412 -23.27688 7.72406   1.000 53.79393 ? 467 HOH   A O   1 
HETATM 2038 O  O   . HOH   E 4 .   ? -13.37050 -22.60597 12.20785  1.000 47.22814 ? 468 HOH   A O   1 
HETATM 2039 O  O   . HOH   E 4 .   ? -52.33170 -27.51748 -2.38432  1.000 55.34792 ? 469 HOH   A O   1 
HETATM 2040 O  O   . HOH   E 4 .   ? -51.81075 -26.69704 1.71284   1.000 53.98040 ? 470 HOH   A O   1 
HETATM 2041 O  O   . HOH   E 4 .   ? -34.52906 0.08292   -6.92262  1.000 68.25206 ? 471 HOH   A O   1 
HETATM 2042 O  O   . HOH   E 4 .   ? -38.83221 -20.79063 15.58862  1.000 51.03426 ? 472 HOH   A O   1 
HETATM 2043 O  O   . HOH   E 4 .   ? -35.63728 -38.66253 -5.31857  1.000 51.67159 ? 473 HOH   A O   1 
HETATM 2044 O  O   . HOH   E 4 .   ? -33.783   -2.149    15.868    1.000 60.69383 ? 474 HOH   A O   1 
HETATM 2045 O  O   . HOH   E 4 .   ? -52.34907 -31.68976 2.18878   1.000 57.51144 ? 475 HOH   A O   1 
HETATM 2046 O  O   . HOH   E 4 .   ? -25.37001 -12.32359 3.55820   1.000 59.52200 ? 476 HOH   A O   1 
HETATM 2047 O  O   . HOH   E 4 .   ? -32.12472 -43.16255 3.62390   1.000 55.60120 ? 477 HOH   A O   1 
HETATM 2048 O  O   . HOH   E 4 .   ? -34.17556 -18.61753 13.80628  1.000 49.99638 ? 478 HOH   A O   1 
HETATM 2049 O  O   . HOH   E 4 .   ? -48.63613 -33.17345 -2.80138  1.000 52.98039 ? 479 HOH   A O   1 
HETATM 2050 O  O   . HOH   E 4 .   ? -39.21296 -21.76321 17.87016  1.000 59.40824 ? 480 HOH   A O   1 
HETATM 2051 O  O   . HOH   E 4 .   ? -34.02370 -36.76041 -5.49317  1.000 52.61723 ? 481 HOH   A O   1 
HETATM 2052 O  O   . HOH   E 4 .   ? -49.16860 -41.51618 3.25818   1.000 55.42500 ? 482 HOH   A O   1 
HETATM 2053 O  O   . HOH   E 4 .   ? -44.060   -34.141   13.363    1.000 50.61663 ? 483 HOH   A O   1 
HETATM 2054 O  O   . HOH   E 4 .   ? -47.33072 -35.08240 -3.17214  1.000 59.12619 ? 484 HOH   A O   1 
HETATM 2055 O  O   . HOH   E 4 .   ? -39.68689 -14.85536 -4.69987  1.000 50.51143 ? 485 HOH   A O   1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . ALA A 2   ? 0.45705 0.40407 0.53788 0.04632  0.01752  0.05267  2   ALA A N   
2    C CA  . ALA A 2   ? 0.48878 0.46127 0.57550 0.04880  0.01977  0.05446  2   ALA A CA  
3    C C   . ALA A 2   ? 0.42656 0.41792 0.51316 0.03387  0.00804  0.04775  2   ALA A C   
4    O O   . ALA A 2   ? 0.44274 0.42247 0.51816 0.02428  0.00069  0.03767  2   ALA A O   
5    C CB  . ALA A 2   ? 0.48094 0.43345 0.54957 0.06082  0.02987  0.04694  2   ALA A CB  
6    N N   . THR A 3   ? 0.38233 0.40240 0.48168 0.03210  0.00594  0.05438  3   THR A N   
7    C CA  . THR A 3   ? 0.39651 0.43111 0.49313 0.02091  -0.00388 0.04785  3   THR A CA  
8    C C   . THR A 3   ? 0.40870 0.44533 0.50019 0.02431  -0.00036 0.04457  3   THR A C   
9    O O   . THR A 3   ? 0.36375 0.41059 0.46589 0.03239  0.00689  0.05491  3   THR A O   
10   C CB  . THR A 3   ? 0.41721 0.47890 0.52897 0.01448  -0.01160 0.05762  3   THR A CB  
11   O OG1 . THR A 3   ? 0.38745 0.44844 0.50353 0.01227  -0.01375 0.06233  3   THR A OG1 
12   C CG2 . THR A 3   ? 0.31350 0.38477 0.41822 0.00498  -0.02128 0.04974  3   THR A CG2 
13   N N   . LEU A 4   ? 0.34962 0.37848 0.42635 0.01860  -0.00508 0.03218  4   LEU A N   
14   C CA  . LEU A 4   ? 0.38558 0.41266 0.45440 0.02200  -0.00141 0.02860  4   LEU A CA  
15   C C   . LEU A 4   ? 0.38518 0.43063 0.45950 0.01356  -0.00998 0.02938  4   LEU A C   
16   O O   . LEU A 4   ? 0.36914 0.41955 0.44233 0.00523  -0.01930 0.02517  4   LEU A O   
17   C CB  . LEU A 4   ? 0.37817 0.38065 0.42401 0.02246  -0.00087 0.01460  4   LEU A CB  
18   C CG  . LEU A 4   ? 0.45699 0.43246 0.49079 0.02959  0.00543  0.01096  4   LEU A CG  
19   C CD1 . LEU A 4   ? 0.48245 0.43330 0.49076 0.02825  0.00332  -0.00309 4   LEU A CD1 
20   C CD2 . LEU A 4   ? 0.42690 0.40102 0.46577 0.04465  0.01896  0.02073  4   LEU A CD2 
21   N N   . PHE A 5   ? 0.36893 0.42354 0.44858 0.01643  -0.00640 0.03564  5   PHE A N   
22   C CA  . PHE A 5   ? 0.32815 0.39490 0.41145 0.00821  -0.01489 0.03679  5   PHE A CA  
23   C C   . PHE A 5   ? 0.36893 0.42994 0.44309 0.01145  -0.01024 0.03422  5   PHE A C   
24   O O   . PHE A 5   ? 0.32578 0.38716 0.40180 0.02090  0.00090  0.04084  5   PHE A O   
25   C CB  . PHE A 5   ? 0.33468 0.42335 0.43922 0.00483  -0.01837 0.05209  5   PHE A CB  
26   C CG  . PHE A 5   ? 0.37262 0.46904 0.48504 0.00136  -0.02406 0.05591  5   PHE A CG  
27   C CD1 . PHE A 5   ? 0.33272 0.43086 0.45417 0.00916  -0.01624 0.06360  5   PHE A CD1 
28   C CD2 . PHE A 5   ? 0.34761 0.44773 0.45589 -0.00836 -0.03672 0.05178  5   PHE A CD2 
29   C CE1 . PHE A 5   ? 0.35869 0.46479 0.48727 0.00603  -0.02152 0.06847  5   PHE A CE1 
30   C CE2 . PHE A 5   ? 0.33087 0.43879 0.44365 -0.01082 -0.04157 0.05574  5   PHE A CE2 
31   C CZ  . PHE A 5   ? 0.31531 0.42744 0.43927 -0.00428 -0.03428 0.06465  5   PHE A CZ  
32   N N   . ILE A 6   ? 0.33222 0.38869 0.39618 0.00500  -0.01797 0.02583  6   ILE A N   
33   C CA  . ILE A 6   ? 0.36141 0.41399 0.41718 0.00684  -0.01520 0.02477  6   ILE A CA  
34   C C   . ILE A 6   ? 0.34719 0.40452 0.40541 -0.00246 -0.02621 0.02503  6   ILE A C   
35   O O   . ILE A 6   ? 0.34886 0.40711 0.40762 -0.00881 -0.03563 0.02136  6   ILE A O   
36   C CB  . ILE A 6   ? 0.33323 0.36753 0.36713 0.01064  -0.01272 0.01183  6   ILE A CB  
37   C CG1 . ILE A 6   ? 0.37921 0.40906 0.40633 0.00355  -0.02299 0.00149  6   ILE A CG1 
38   C CG2 . ILE A 6   ? 0.36027 0.38228 0.38643 0.01983  -0.00285 0.01003  6   ILE A CG2 
39   C CD1 . ILE A 6   ? 0.35707 0.37270 0.36575 0.00454  -0.02369 -0.00938 6   ILE A CD1 
40   N N   . ALA A 7   ? 0.32383 0.38231 0.38157 -0.00246 -0.02465 0.02967  7   ALA A N   
41   C CA  . ALA A 7   ? 0.36190 0.41934 0.41976 -0.01094 -0.03519 0.03003  7   ALA A CA  
42   C C   . ALA A 7   ? 0.41496 0.47060 0.46874 -0.00855 -0.03062 0.03438  7   ALA A C   
43   O O   . ALA A 7   ? 0.37840 0.43739 0.43115 -0.00025 -0.01888 0.03929  7   ALA A O   
44   C CB  . ALA A 7   ? 0.33579 0.40490 0.41105 -0.01975 -0.04352 0.04102  7   ALA A CB  
45   N N   . ASP A 8   ? 0.36329 0.41215 0.41291 -0.01488 -0.03965 0.03283  8   ASP A N   
46   C CA  . ASP A 8   ? 0.38322 0.43196 0.43260 -0.01498 -0.03744 0.04058  8   ASP A CA  
47   C C   . ASP A 8   ? 0.39860 0.44253 0.43209 -0.00485 -0.02703 0.03558  8   ASP A C   
48   O O   . ASP A 8   ? 0.37872 0.42950 0.41372 0.00038  -0.01754 0.04536  8   ASP A O   
49   C CB  . ASP A 8   ? 0.40114 0.46720 0.47275 -0.01897 -0.03504 0.05990  8   ASP A CB  
50   C CG  . ASP A 8   ? 0.41954 0.48870 0.50470 -0.03138 -0.04864 0.06480  8   ASP A CG  
51   O OD1 . ASP A 8   ? 0.43077 0.48504 0.50796 -0.03910 -0.06093 0.05920  8   ASP A OD1 
52   O OD2 . ASP A 8   ? 0.45591 0.54057 0.55756 -0.03288 -0.04761 0.07384  8   ASP A OD2 
53   N N   . LEU A 9   ? 0.40172 0.43451 0.41911 -0.00219 -0.02933 0.02095  9   LEU A N   
54   C CA  . LEU A 9   ? 0.41594 0.44122 0.41480 0.00470  -0.02405 0.01456  9   LEU A CA  
55   C C   . LEU A 9   ? 0.40070 0.42146 0.39228 0.00340  -0.02837 0.01597  9   LEU A C   
56   O O   . LEU A 9   ? 0.38641 0.40558 0.36600 0.00889  -0.02252 0.01769  9   LEU A O   
57   C CB  . LEU A 9   ? 0.38467 0.40211 0.37238 0.00557  -0.02714 0.00087  9   LEU A CB  
58   C CG  . LEU A 9   ? 0.42491 0.44201 0.41484 0.00861  -0.02139 -0.00103 9   LEU A CG  
59   C CD1 . LEU A 9   ? 0.38964 0.41415 0.39587 0.00326  -0.02628 0.00106  9   LEU A CD1 
60   C CD2 . LEU A 9   ? 0.40080 0.40610 0.37375 0.01032  -0.02242 -0.01257 9   LEU A CD2 
61   N N   . HIS A 10  ? 0.38747 0.40428 0.38385 -0.00284 -0.03844 0.01530  10  HIS A N   
62   C CA  . HIS A 10  ? 0.40937 0.41888 0.39937 -0.00352 -0.04332 0.01711  10  HIS A CA  
63   C C   . HIS A 10  ? 0.39800 0.40378 0.37049 0.00272  -0.04179 0.00979  10  HIS A C   
64   O O   . HIS A 10  ? 0.42707 0.43207 0.39209 0.00560  -0.03926 0.01512  10  HIS A O   
65   C CB  . HIS A 10  ? 0.46262 0.47695 0.46197 -0.00607 -0.04024 0.03267  10  HIS A CB  
66   C CG  . HIS A 10  ? 0.45404 0.47465 0.47297 -0.01439 -0.04377 0.04243  10  HIS A CG  
67   N ND1 . HIS A 10  ? 0.53647 0.54753 0.56129 -0.02362 -0.05553 0.04563  10  HIS A ND1 
68   C CD2 . HIS A 10  ? 0.49780 0.53272 0.53124 -0.01505 -0.03810 0.05030  10  HIS A CD2 
69   C CE1 . HIS A 10  ? 0.48741 0.50747 0.52963 -0.03149 -0.05851 0.05500  10  HIS A CE1 
70   N NE2 . HIS A 10  ? 0.52155 0.55847 0.57109 -0.02601 -0.04755 0.05895  10  HIS A NE2 
71   N N   . LEU A 11  ? 0.40223 0.40710 0.36874 0.00404  -0.04412 -0.00114 11  LEU A N   
72   C CA  . LEU A 11  ? 0.42506 0.42818 0.37658 0.00770  -0.04529 -0.00731 11  LEU A CA  
73   C C   . LEU A 11  ? 0.46919 0.46929 0.41659 0.00919  -0.05089 -0.00493 11  LEU A C   
74   O O   . LEU A 11  ? 0.42206 0.41805 0.37586 0.00803  -0.05611 -0.00435 11  LEU A O   
75   C CB  . LEU A 11  ? 0.39310 0.39803 0.34397 0.00644  -0.04889 -0.01673 11  LEU A CB  
76   C CG  . LEU A 11  ? 0.43525 0.44004 0.38829 0.00562  -0.04364 -0.01923 11  LEU A CG  
77   C CD1 . LEU A 11  ? 0.40304 0.41006 0.35828 0.00273  -0.04837 -0.02621 11  LEU A CD1 
78   C CD2 . LEU A 11  ? 0.42984 0.42860 0.36805 0.00978  -0.03683 -0.01948 11  LEU A CD2 
79   N N   . GLN A 12  ? 0.43893 0.43918 0.37337 0.01260  -0.04987 -0.00348 12  GLN A N   
80   C CA  . GLN A 12  ? 0.49206 0.49036 0.42203 0.01526  -0.05435 0.00087  12  GLN A CA  
81   C C   . GLN A 12  ? 0.49936 0.50072 0.41249 0.01824  -0.05475 -0.00059 12  GLN A C   
82   O O   . GLN A 12  ? 0.45867 0.45916 0.36072 0.01905  -0.04925 -0.00188 12  GLN A O   
83   C CB  . GLN A 12  ? 0.52708 0.52085 0.46272 0.01439  -0.05207 0.01246  12  GLN A CB  
84   C CG  . GLN A 12  ? 0.48964 0.48820 0.42409 0.01464  -0.04258 0.01992  12  GLN A CG  
85   C CD  . GLN A 12  ? 0.59080 0.58908 0.53758 0.01121  -0.04076 0.03425  12  GLN A CD  
86   O OE1 . GLN A 12  ? 0.62902 0.63212 0.58915 0.00734  -0.03714 0.03974  12  GLN A OE1 
87   N NE2 . GLN A 12  ? 0.55421 0.54793 0.49792 0.01208  -0.04373 0.04205  12  GLN A NE2 
88   N N   . THR A 13  ? 0.46420 0.46841 0.37392 0.02063  -0.06154 -0.00013 13  THR A N   
89   C CA  . THR A 13  ? 0.50061 0.50913 0.39413 0.02185  -0.06494 -0.00128 13  THR A CA  
90   C C   . THR A 13  ? 0.52602 0.53130 0.40477 0.02484  -0.05943 0.00565  13  THR A C   
91   O O   . THR A 13  ? 0.53304 0.53825 0.39221 0.02559  -0.06073 0.00290  13  THR A O   
92   C CB  . THR A 13  ? 0.60415 0.62041 0.50066 0.02460  -0.07335 0.00114  13  THR A CB  
93   O OG1 . THR A 13  ? 0.58019 0.59139 0.48363 0.02921  -0.07263 0.00923  13  THR A OG1 
94   C CG2 . THR A 13  ? 0.52893 0.55281 0.43767 0.02281  -0.07765 -0.00489 13  THR A CG2 
95   N N   . GLU A 14  ? 0.51828 0.52060 0.40495 0.02612  -0.05378 0.01521  14  GLU A N   
96   C CA  . GLU A 14  ? 0.56846 0.57098 0.44370 0.02952  -0.04649 0.02467  14  GLU A CA  
97   C C   . GLU A 14  ? 0.55351 0.55525 0.42046 0.03113  -0.03641 0.02222  14  GLU A C   
98   O O   . GLU A 14  ? 0.57046 0.57350 0.42318 0.03634  -0.02863 0.02925  14  GLU A O   
99   C CB  . GLU A 14  ? 0.54851 0.54930 0.43840 0.02878  -0.04450 0.03836  14  GLU A CB  
100  C CG  . GLU A 14  ? 0.60648 0.60383 0.49902 0.03040  -0.05265 0.04314  14  GLU A CG  
101  C CD  . GLU A 14  ? 0.75479 0.74584 0.66102 0.02867  -0.05946 0.03634  14  GLU A CD  
102  O OE1 . GLU A 14  ? 0.60671 0.59742 0.52064 0.02498  -0.05853 0.02821  14  GLU A OE1 
103  O OE2 . GLU A 14  ? 0.88728 0.87331 0.79521 0.03232  -0.06513 0.03963  14  GLU A OE2 
104  N N   . GLU A 15  ? 0.49841 0.49812 0.37293 0.02832  -0.03543 0.01345  15  GLU A N   
105  C CA  . GLU A 15  ? 0.53968 0.53708 0.40744 0.03172  -0.02510 0.01143  15  GLU A CA  
106  C C   . GLU A 15  ? 0.56390 0.55308 0.41908 0.03027  -0.02926 -0.00341 15  GLU A C   
107  O O   . GLU A 15  ? 0.49945 0.48711 0.36626 0.02766  -0.02820 -0.00839 15  GLU A O   
108  C CB  . GLU A 15  ? 0.48883 0.49158 0.38109 0.02938  -0.01936 0.01845  15  GLU A CB  
109  C CG  . GLU A 15  ? 0.56159 0.57183 0.46694 0.02901  -0.01516 0.03536  15  GLU A CG  
110  C CD  . GLU A 15  ? 0.68825 0.70337 0.57863 0.03746  -0.00329 0.04523  15  GLU A CD  
111  O OE1 . GLU A 15  ? 0.68270 0.69441 0.55505 0.04492  0.00484  0.03912  15  GLU A OE1 
112  O OE2 . GLU A 15  ? 0.79025 0.81135 0.68576 0.03727  -0.00173 0.05963  15  GLU A OE2 
113  N N   . PRO A 16  ? 0.52593 0.50917 0.35700 0.03096  -0.03511 -0.00984 16  PRO A N   
114  C CA  . PRO A 16  ? 0.55956 0.53337 0.37979 0.02654  -0.04228 -0.02307 16  PRO A CA  
115  C C   . PRO A 16  ? 0.58516 0.54504 0.39298 0.03086  -0.03317 -0.02931 16  PRO A C   
116  O O   . PRO A 16  ? 0.57114 0.52227 0.37839 0.02592  -0.03825 -0.03872 16  PRO A O   
117  C CB  . PRO A 16  ? 0.54402 0.51480 0.33956 0.02547  -0.05193 -0.02605 16  PRO A CB  
118  C CG  . PRO A 16  ? 0.61115 0.58464 0.39450 0.03348  -0.04403 -0.01608 16  PRO A CG  
119  C CD  . PRO A 16  ? 0.58207 0.56677 0.39439 0.03467  -0.03679 -0.00436 16  PRO A CD  
120  N N   . ALA A 17  ? 0.58197 0.54008 0.38097 0.04066  -0.01926 -0.02297 17  ALA A N   
121  C CA  . ALA A 17  ? 0.56332 0.50806 0.35080 0.04792  -0.00860 -0.02777 17  ALA A CA  
122  C C   . ALA A 17  ? 0.58253 0.53311 0.39956 0.04438  -0.00636 -0.02652 17  ALA A C   
123  O O   . ALA A 17  ? 0.54237 0.47920 0.35325 0.04557  -0.00467 -0.03458 17  ALA A O   
124  C CB  . ALA A 17  ? 0.59416 0.54099 0.36866 0.06147  0.00785  -0.01802 17  ALA A CB  
125  N N   . ILE A 18  ? 0.52850 0.49725 0.37588 0.03987  -0.00710 -0.01643 18  ILE A N   
126  C CA  . ILE A 18  ? 0.51787 0.49284 0.39158 0.03544  -0.00716 -0.01522 18  ILE A CA  
127  C C   . ILE A 18  ? 0.52166 0.49119 0.39772 0.02684  -0.01918 -0.02628 18  ILE A C   
128  O O   . ILE A 18  ? 0.51266 0.47783 0.39565 0.02547  -0.01825 -0.03016 18  ILE A O   
129  C CB  . ILE A 18  ? 0.49525 0.48701 0.39609 0.03131  -0.00781 -0.00286 18  ILE A CB  
130  C CG1 . ILE A 18  ? 0.54312 0.54333 0.44453 0.03807  0.00325  0.01132  18  ILE A CG1 
131  C CG2 . ILE A 18  ? 0.47344 0.47126 0.39812 0.02688  -0.00842 -0.00138 18  ILE A CG2 
132  C CD1 . ILE A 18  ? 0.57449 0.58804 0.50176 0.03152  0.00023  0.02450  18  ILE A CD1 
133  N N   . THR A 19  ? 0.49149 0.46345 0.36374 0.02132  -0.03024 -0.02947 19  THR A N   
134  C CA  . THR A 19  ? 0.50026 0.47129 0.37587 0.01338  -0.04137 -0.03729 19  THR A CA  
135  C C   . THR A 19  ? 0.53667 0.48947 0.39252 0.01245  -0.04272 -0.04690 19  THR A C   
136  O O   . THR A 19  ? 0.47331 0.42299 0.33796 0.00740  -0.04589 -0.05078 19  THR A O   
137  C CB  . THR A 19  ? 0.51507 0.49410 0.38870 0.00980  -0.05182 -0.03664 19  THR A CB  
138  O OG1 . THR A 19  ? 0.49119 0.48202 0.38244 0.01103  -0.05115 -0.02868 19  THR A OG1 
139  C CG2 . THR A 19  ? 0.44203 0.42441 0.32075 0.00170  -0.06302 -0.04203 19  THR A CG2 
140  N N   . ALA A 20  ? 0.52039 0.45874 0.34718 0.01736  -0.04075 -0.05075 20  ALA A N   
141  C CA  . ALA A 20  ? 0.58026 0.49392 0.38211 0.01707  -0.04269 -0.06138 20  ALA A CA  
142  C C   . ALA A 20  ? 0.58850 0.49253 0.39603 0.02329  -0.03128 -0.06167 20  ALA A C   
143  O O   . ALA A 20  ? 0.59377 0.48182 0.39718 0.01898  -0.03550 -0.06874 20  ALA A O   
144  C CB  . ALA A 20  ? 0.58034 0.47786 0.34489 0.02370  -0.04119 -0.06566 20  ALA A CB  
145  N N   . GLY A 21  ? 0.57214 0.48668 0.39085 0.03303  -0.01728 -0.05234 21  GLY A N   
146  C CA  . GLY A 21  ? 0.55232 0.46284 0.38073 0.03980  -0.00618 -0.04968 21  GLY A CA  
147  C C   . GLY A 21  ? 0.57207 0.49162 0.42819 0.03062  -0.01237 -0.04878 21  GLY A C   
148  O O   . GLY A 21  ? 0.54443 0.45098 0.40034 0.03181  -0.01014 -0.05208 21  GLY A O   
149  N N   . PHE A 22  ? 0.47422 0.41469 0.35271 0.02246  -0.01977 -0.04401 22  PHE A N   
150  C CA  . PHE A 22  ? 0.48108 0.43111 0.38290 0.01490  -0.02521 -0.04291 22  PHE A CA  
151  C C   . PHE A 22  ? 0.50482 0.44283 0.39885 0.00672  -0.03541 -0.05145 22  PHE A C   
152  O O   . PHE A 22  ? 0.47250 0.40765 0.37677 0.00370  -0.03594 -0.05159 22  PHE A O   
153  C CB  . PHE A 22  ? 0.43091 0.40170 0.35196 0.01005  -0.03058 -0.03723 22  PHE A CB  
154  C CG  . PHE A 22  ? 0.40673 0.38822 0.34859 0.00425  -0.03504 -0.03564 22  PHE A CG  
155  C CD1 . PHE A 22  ? 0.42112 0.40271 0.37405 0.00570  -0.02974 -0.03245 22  PHE A CD1 
156  C CD2 . PHE A 22  ? 0.42377 0.41615 0.37319 -0.00113 -0.04379 -0.03629 22  PHE A CD2 
157  C CE1 . PHE A 22  ? 0.39862 0.39074 0.36838 0.00077  -0.03388 -0.03033 22  PHE A CE1 
158  C CE2 . PHE A 22  ? 0.39685 0.39928 0.36204 -0.00461 -0.04666 -0.03456 22  PHE A CE2 
159  C CZ  . PHE A 22  ? 0.42762 0.42974 0.40220 -0.00423 -0.04211 -0.03179 22  PHE A CZ  
160  N N   . LEU A 23  ? 0.52127 0.45291 0.39789 0.00230  -0.04430 -0.05712 23  LEU A N   
161  C CA  . LEU A 23  ? 0.52971 0.45119 0.39991 -0.00796 -0.05634 -0.06340 23  LEU A CA  
162  C C   . LEU A 23  ? 0.61148 0.50341 0.46369 -0.00596 -0.05346 -0.07015 23  LEU A C   
163  O O   . LEU A 23  ? 0.58217 0.46697 0.44089 -0.01410 -0.05988 -0.07165 23  LEU A O   
164  C CB  . LEU A 23  ? 0.57073 0.49184 0.42439 -0.01294 -0.06714 -0.06671 23  LEU A CB  
165  C CG  . LEU A 23  ? 0.56958 0.51815 0.44144 -0.01624 -0.07314 -0.06006 23  LEU A CG  
166  C CD1 . LEU A 23  ? 0.60325 0.55200 0.46025 -0.02258 -0.08592 -0.06216 23  LEU A CD1 
167  C CD2 . LEU A 23  ? 0.55392 0.52101 0.45387 -0.02163 -0.07597 -0.05508 23  LEU A CD2 
168  N N   . ARG A 24  ? 0.54825 0.42168 0.37680 0.00577  -0.04330 -0.07354 24  ARG A N   
169  C CA  . ARG A 24  ? 0.61373 0.45527 0.42231 0.01148  -0.03822 -0.08016 24  ARG A CA  
170  C C   . ARG A 24  ? 0.62345 0.47137 0.45675 0.01534  -0.02943 -0.07331 24  ARG A C   
171  O O   . ARG A 24  ? 0.66244 0.48951 0.49196 0.01302  -0.03149 -0.07692 24  ARG A O   
172  C CB  . ARG A 24  ? 0.68018 0.50326 0.45695 0.02681  -0.02656 -0.08392 24  ARG A CB  
173  C CG  . ARG A 24  ? 0.79060 0.57927 0.54473 0.03821  -0.01715 -0.09001 24  ARG A CG  
174  C CD  . ARG A 24  ? 0.87729 0.64512 0.59218 0.05417  -0.00663 -0.09531 24  ARG A CD  
175  N NE  . ARG A 24  ? 0.84401 0.62700 0.57002 0.07238  0.01441  -0.08413 24  ARG A NE  
176  C CZ  . ARG A 24  ? 0.99111 0.76122 0.71729 0.08597  0.02804  -0.08172 24  ARG A CZ  
177  N NH1 . ARG A 24  ? 1.07511 0.81156 0.78725 0.08451  0.02354  -0.09112 24  ARG A NH1 
178  N NH2 . ARG A 24  ? 0.87353 0.66545 0.61551 0.10132  0.04632  -0.06810 24  ARG A NH2 
179  N N   . PHE A 25  ? 0.56446 0.44002 0.42269 0.02057  -0.02067 -0.06273 25  PHE A N   
180  C CA  . PHE A 25  ? 0.55032 0.43650 0.43381 0.02290  -0.01431 -0.05465 25  PHE A CA  
181  C C   . PHE A 25  ? 0.57512 0.46666 0.47535 0.00968  -0.02564 -0.05466 25  PHE A C   
182  O O   . PHE A 25  ? 0.58627 0.46842 0.49302 0.00998  -0.02372 -0.05294 25  PHE A O   
183  C CB  . PHE A 25  ? 0.54178 0.45776 0.44841 0.02676  -0.00758 -0.04322 25  PHE A CB  
184  C CG  . PHE A 25  ? 0.51010 0.44255 0.44480 0.02567  -0.00523 -0.03406 25  PHE A CG  
185  C CD1 . PHE A 25  ? 0.52422 0.45415 0.46456 0.03646  0.00665  -0.02716 25  PHE A CD1 
186  C CD2 . PHE A 25  ? 0.44338 0.39481 0.39770 0.01523  -0.01445 -0.03147 25  PHE A CD2 
187  C CE1 . PHE A 25  ? 0.50082 0.44772 0.46702 0.03498  0.00757  -0.01748 25  PHE A CE1 
188  C CE2 . PHE A 25  ? 0.45146 0.41737 0.42790 0.01419  -0.01322 -0.02329 25  PHE A CE2 
189  C CZ  . PHE A 25  ? 0.50270 0.46698 0.48577 0.02315  -0.00304 -0.01604 25  PHE A CZ  
190  N N   . LEU A 26  ? 0.51837 0.42596 0.42604 -0.00095 -0.03677 -0.05515 26  LEU A N   
191  C CA  . LEU A 26  ? 0.55957 0.47763 0.48464 -0.01239 -0.04625 -0.05275 26  LEU A CA  
192  C C   . LEU A 26  ? 0.60120 0.49378 0.51284 -0.02031 -0.05445 -0.05865 26  LEU A C   
193  O O   . LEU A 26  ? 0.58564 0.47944 0.51142 -0.02681 -0.05783 -0.05457 26  LEU A O   
194  C CB  . LEU A 26  ? 0.48972 0.43150 0.42444 -0.01898 -0.05456 -0.05082 26  LEU A CB  
195  C CG  . LEU A 26  ? 0.43914 0.40450 0.38979 -0.01418 -0.04979 -0.04461 26  LEU A CG  
196  C CD1 . LEU A 26  ? 0.46606 0.44939 0.42261 -0.01898 -0.05799 -0.04357 26  LEU A CD1 
197  C CD2 . LEU A 26  ? 0.41783 0.39347 0.38763 -0.01309 -0.04537 -0.03811 26  LEU A CD2 
198  N N   . GLN A 27  ? 0.61237 0.48070 0.49557 -0.02078 -0.05885 -0.06778 27  GLN A N   
199  C CA  . GLN A 27  ? 0.67974 0.51861 0.54622 -0.03045 -0.06962 -0.07441 27  GLN A CA  
200  C C   . GLN A 27  ? 0.66894 0.47526 0.52307 -0.02245 -0.06151 -0.07755 27  GLN A C   
201  O O   . GLN A 27  ? 0.74055 0.52345 0.58925 -0.03173 -0.07026 -0.08008 27  GLN A O   
202  C CB  . GLN A 27  ? 0.69256 0.51351 0.52821 -0.03408 -0.07896 -0.08397 27  GLN A CB  
203  C CG  . GLN A 27  ? 0.80974 0.65441 0.65676 -0.04845 -0.09424 -0.08058 27  GLN A CG  
204  N N   . GLY A 28  ? 0.61795 0.42244 0.46856 -0.00543 -0.04520 -0.07605 28  GLY A N   
205  C CA  . GLY A 28  ? 0.68900 0.46270 0.52676 0.00572  -0.03554 -0.07810 28  GLY A CA  
206  C C   . GLY A 28  ? 0.68961 0.48288 0.55759 0.01198  -0.02530 -0.06600 28  GLY A C   
207  O O   . GLY A 28  ? 0.75245 0.54287 0.63490 0.00440  -0.03021 -0.06178 28  GLY A O   
208  N N   . GLU A 29  ? 0.70442 0.51965 0.58318 0.02474  -0.01205 -0.05885 29  GLU A N   
209  C CA  . GLU A 29  ? 0.70314 0.53572 0.60778 0.03231  -0.00203 -0.04656 29  GLU A CA  
210  C C   . GLU A 29  ? 0.65188 0.51190 0.58670 0.01896  -0.01090 -0.03879 29  GLU A C   
211  O O   . GLU A 29  ? 0.58136 0.44010 0.52993 0.01863  -0.00979 -0.03226 29  GLU A O   
212  C CB  . GLU A 29  ? 0.69019 0.54575 0.60290 0.04493  0.01074  -0.03867 29  GLU A CB  
213  C CG  . GLU A 29  ? 0.75520 0.63099 0.69491 0.05277  0.02033  -0.02423 29  GLU A CG  
214  C CD  . GLU A 29  ? 0.82011 0.67226 0.74815 0.07076  0.03453  -0.02206 29  GLU A CD  
215  O OE1 . GLU A 29  ? 0.87526 0.70553 0.77540 0.08272  0.04266  -0.02889 29  GLU A OE1 
216  O OE2 . GLU A 29  ? 0.81030 0.66544 0.75568 0.07420  0.03805  -0.01312 29  GLU A OE2 
217  N N   . ALA A 30  ? 0.62676 0.51122 0.57068 0.00922  -0.01911 -0.03888 30  ALA A N   
218  C CA  . ALA A 30  ? 0.53752 0.45031 0.50750 0.00035  -0.02485 -0.03101 30  ALA A CA  
219  C C   . ALA A 30  ? 0.54754 0.45161 0.52227 -0.01023 -0.03330 -0.03026 30  ALA A C   
220  O O   . ALA A 30  ? 0.48583 0.40795 0.48091 -0.01360 -0.03414 -0.02141 30  ALA A O   
221  C CB  . ALA A 30  ? 0.48954 0.42496 0.46361 -0.00552 -0.03115 -0.03234 30  ALA A CB  
222  N N   . ARG A 31  ? 0.53863 0.41491 0.49422 -0.01625 -0.04037 -0.03852 31  ARG A N   
223  C CA  . ARG A 31  ? 0.56979 0.43739 0.53142 -0.02883 -0.05012 -0.03604 31  ARG A CA  
224  C C   . ARG A 31  ? 0.60398 0.45757 0.57290 -0.02397 -0.04401 -0.02943 31  ARG A C   
225  O O   . ARG A 31  ? 0.61841 0.47492 0.60115 -0.03389 -0.05029 -0.02238 31  ARG A O   
226  C CB  . ARG A 31  ? 0.60548 0.44208 0.54266 -0.03777 -0.06110 -0.04637 31  ARG A CB  
227  C CG  . ARG A 31  ? 0.68429 0.53362 0.61299 -0.04219 -0.06783 -0.05199 31  ARG A CG  
228  C CD  . ARG A 31  ? 0.68452 0.56696 0.63624 -0.05510 -0.07767 -0.04417 31  ARG A CD  
229  N NE  . ARG A 31  ? 0.71094 0.60551 0.65543 -0.05859 -0.08445 -0.04823 31  ARG A NE  
230  C CZ  . ARG A 31  ? 0.69268 0.58901 0.63629 -0.07267 -0.09887 -0.04794 31  ARG A CZ  
231  N NH1 . ARG A 31  ? 0.57736 0.46262 0.52645 -0.08605 -0.10877 -0.04401 31  ARG A NH1 
232  N NH2 . ARG A 31  ? 0.64994 0.55979 0.58804 -0.07395 -0.10418 -0.05023 31  ARG A NH2 
233  N N   . GLN A 32  ? 0.60215 0.44212 0.56326 -0.00835 -0.03147 -0.02979 32  GLN A N   
234  C CA  . GLN A 32  ? 0.63823 0.46488 0.60646 -0.00108 -0.02445 -0.02228 32  GLN A CA  
235  C C   . GLN A 32  ? 0.61392 0.47653 0.60996 0.00426  -0.01752 -0.00861 32  GLN A C   
236  O O   . GLN A 32  ? 0.55072 0.40822 0.55633 0.01074  -0.01167 0.00022  32  GLN A O   
237  C CB  . GLN A 32  ? 0.70206 0.49220 0.64524 0.01539  -0.01364 -0.02890 32  GLN A CB  
238  C CG  . GLN A 32  ? 0.78160 0.53427 0.68979 0.01224  -0.02023 -0.04462 32  GLN A CG  
239  C CD  . GLN A 32  ? 0.92804 0.65529 0.83015 -0.00524 -0.03588 -0.04817 32  GLN A CD  
240  O OE1 . GLN A 32  ? 0.96046 0.67859 0.87483 -0.00831 -0.03700 -0.04047 32  GLN A OE1 
241  N NE2 . GLN A 32  ? 0.98837 0.70497 0.87258 -0.01762 -0.04888 -0.05829 32  GLN A NE2 
242  N N   . ALA A 33  ? 0.53832 0.43513 0.54620 0.00146  -0.01905 -0.00646 33  ALA A N   
243  C CA  . ALA A 33  ? 0.49978 0.42752 0.52929 0.00611  -0.01414 0.00509  33  ALA A CA  
244  C C   . ALA A 33  ? 0.51989 0.46651 0.56734 -0.00324 -0.02057 0.01399  33  ALA A C   
245  O O   . ALA A 33  ? 0.49086 0.43725 0.53763 -0.01451 -0.02914 0.01173  33  ALA A O   
246  C CB  . ALA A 33  ? 0.41829 0.36940 0.44958 0.00671  -0.01418 0.00312  33  ALA A CB  
247  N N   . ASP A 34  ? 0.47355 0.43829 0.53758 0.00182  -0.01629 0.02583  34  ASP A N   
248  C CA  . ASP A 34  ? 0.41941 0.40827 0.49853 -0.00548 -0.02176 0.03486  34  ASP A CA  
249  C C   . ASP A 34  ? 0.45508 0.46824 0.53426 -0.01115 -0.02758 0.03101  34  ASP A C   
250  O O   . ASP A 34  ? 0.41468 0.44230 0.49847 -0.01821 -0.03300 0.03392  34  ASP A O   
251  C CB  . ASP A 34  ? 0.41056 0.41375 0.50513 0.00141  -0.01699 0.04860  34  ASP A CB  
252  C CG  . ASP A 34  ? 0.39182 0.37110 0.48769 0.00912  -0.01031 0.05448  34  ASP A CG  
253  O OD1 . ASP A 34  ? 0.48634 0.43984 0.57397 0.00470  -0.01264 0.05047  34  ASP A OD1 
254  O OD2 . ASP A 34  ? 0.49084 0.47669 0.59635 0.01953  -0.00327 0.06403  34  ASP A OD2 
255  N N   . ALA A 35  ? 0.42095 0.43837 0.49473 -0.00723 -0.02593 0.02551  35  ALA A N   
256  C CA  . ALA A 35  ? 0.39416 0.42957 0.46585 -0.01105 -0.03123 0.02146  35  ALA A CA  
257  C C   . ALA A 35  ? 0.41111 0.44188 0.47509 -0.00686 -0.02868 0.01528  35  ALA A C   
258  O O   . ALA A 35  ? 0.39846 0.42158 0.46330 0.00028  -0.02178 0.01798  35  ALA A O   
259  C CB  . ALA A 35  ? 0.40001 0.45836 0.48129 -0.01165 -0.03398 0.02983  35  ALA A CB  
260  N N   . LEU A 36  ? 0.34868 0.38552 0.40579 -0.01025 -0.03352 0.00856  36  LEU A N   
261  C CA  . LEU A 36  ? 0.40547 0.43957 0.45562 -0.00746 -0.03218 0.00388  36  LEU A CA  
262  C C   . LEU A 36  ? 0.37814 0.42751 0.43040 -0.00984 -0.03762 0.00470  36  LEU A C   
263  O O   . LEU A 36  ? 0.35711 0.41293 0.40580 -0.01296 -0.04287 0.00153  36  LEU A O   
264  C CB  . LEU A 36  ? 0.38370 0.40432 0.41969 -0.00891 -0.03364 -0.00585 36  LEU A CB  
265  C CG  . LEU A 36  ? 0.41224 0.43186 0.44026 -0.00634 -0.03288 -0.00982 36  LEU A CG  
266  C CD1 . LEU A 36  ? 0.36707 0.38209 0.39629 0.00101  -0.02433 -0.00514 36  LEU A CD1 
267  C CD2 . LEU A 36  ? 0.37666 0.38569 0.39042 -0.00854 -0.03615 -0.01848 36  LEU A CD2 
268  N N   . TYR A 37  ? 0.32438 0.37881 0.38196 -0.00807 -0.03646 0.00970  37  TYR A N   
269  C CA  . TYR A 37  ? 0.35239 0.41539 0.40963 -0.01162 -0.04334 0.01019  37  TYR A CA  
270  C C   . TYR A 37  ? 0.38520 0.44248 0.43743 -0.01088 -0.04259 0.00755  37  TYR A C   
271  O O   . TYR A 37  ? 0.35315 0.40925 0.41023 -0.00722 -0.03603 0.01257  37  TYR A O   
272  C CB  . TYR A 37  ? 0.33641 0.41186 0.40628 -0.01340 -0.04583 0.02096  37  TYR A CB  
273  C CG  . TYR A 37  ? 0.39662 0.47998 0.46963 -0.01469 -0.04847 0.02457  37  TYR A CG  
274  C CD1 . TYR A 37  ? 0.34077 0.42314 0.42103 -0.01136 -0.04225 0.02936  37  TYR A CD1 
275  C CD2 . TYR A 37  ? 0.36648 0.45628 0.43308 -0.01861 -0.05715 0.02353  37  TYR A CD2 
276  C CE1 . TYR A 37  ? 0.34846 0.43917 0.43255 -0.01265 -0.04443 0.03466  37  TYR A CE1 
277  C CE2 . TYR A 37  ? 0.39039 0.48894 0.45807 -0.01892 -0.05888 0.02792  37  TYR A CE2 
278  C CZ  . TYR A 37  ? 0.42931 0.52990 0.50735 -0.01631 -0.05241 0.03435  37  TYR A CZ  
279  O OH  . TYR A 37  ? 0.42115 0.53149 0.50132 -0.01676 -0.05391 0.04069  37  TYR A OH  
280  N N   . ILE A 38  ? 0.34473 0.39898 0.38721 -0.01311 -0.04848 0.00099  38  ILE A N   
281  C CA  . ILE A 38  ? 0.34341 0.39198 0.38102 -0.01306 -0.04901 -0.00044 38  ILE A CA  
282  C C   . ILE A 38  ? 0.38662 0.43728 0.42595 -0.01822 -0.05744 0.00289  38  ILE A C   
283  O O   . ILE A 38  ? 0.35735 0.40418 0.38697 -0.01951 -0.06431 -0.00288 38  ILE A O   
284  C CB  . ILE A 38  ? 0.37442 0.41527 0.39902 -0.01115 -0.04977 -0.00963 38  ILE A CB  
285  C CG1 . ILE A 38  ? 0.39102 0.42853 0.41309 -0.00911 -0.04501 -0.01292 38  ILE A CG1 
286  C CG2 . ILE A 38  ? 0.36994 0.40478 0.38961 -0.01030 -0.04928 -0.00950 38  ILE A CG2 
287  C CD1 . ILE A 38  ? 0.32915 0.36172 0.34040 -0.00860 -0.04695 -0.01991 38  ILE A CD1 
288  N N   . LEU A 39  ? 0.35161 0.37376 0.35904 0.00274  -0.01933 -0.03199 39  LEU A N   
289  C CA  . LEU A 39  ? 0.36314 0.38713 0.37947 0.00239  -0.02423 -0.03870 39  LEU A CA  
290  C C   . LEU A 39  ? 0.39327 0.41114 0.42015 -0.00127 -0.02432 -0.03925 39  LEU A C   
291  O O   . LEU A 39  ? 0.35658 0.37492 0.39703 -0.00436 -0.02599 -0.04077 39  LEU A O   
292  C CB  . LEU A 39  ? 0.38152 0.41181 0.40439 0.00171  -0.02606 -0.03963 39  LEU A CB  
293  C CG  . LEU A 39  ? 0.41473 0.45083 0.42723 0.00574  -0.02556 -0.03854 39  LEU A CG  
294  C CD1 . LEU A 39  ? 0.40020 0.44328 0.42054 0.00561  -0.02846 -0.04060 39  LEU A CD1 
295  C CD2 . LEU A 39  ? 0.34705 0.38432 0.34838 0.01161  -0.02755 -0.04244 39  LEU A CD2 
296  N N   . GLY A 40  ? 0.37714 0.38932 0.39939 -0.00084 -0.02234 -0.03765 40  GLY A N   
297  C CA  . GLY A 40  ? 0.35894 0.36486 0.38985 -0.00304 -0.02292 -0.03921 40  GLY A CA  
298  C C   . GLY A 40  ? 0.41981 0.42071 0.45539 -0.00591 -0.01760 -0.03197 40  GLY A C   
299  O O   . GLY A 40  ? 0.38019 0.38286 0.41512 -0.00654 -0.01417 -0.02654 40  GLY A O   
300  N N   . ASP A 41  ? 0.38413 0.37815 0.42340 -0.00657 -0.01674 -0.03184 41  ASP A N   
301  C CA  . ASP A 41  ? 0.37553 0.36344 0.41741 -0.00752 -0.01128 -0.02478 41  ASP A CA  
302  C C   . ASP A 41  ? 0.39358 0.38111 0.42235 -0.00490 -0.00809 -0.01916 41  ASP A C   
303  O O   . ASP A 41  ? 0.37670 0.36209 0.40469 -0.00429 -0.00381 -0.01290 41  ASP A O   
304  C CB  . ASP A 41  ? 0.39752 0.38572 0.45422 -0.01060 -0.00859 -0.02140 41  ASP A CB  
305  C CG  . ASP A 41  ? 0.46415 0.44954 0.53738 -0.01367 -0.01157 -0.02615 41  ASP A CG  
306  O OD1 . ASP A 41  ? 0.47134 0.45427 0.54209 -0.01271 -0.01635 -0.03295 41  ASP A OD1 
307  O OD2 . ASP A 41  ? 0.45107 0.43640 0.54056 -0.01670 -0.00907 -0.02291 41  ASP A OD2 
308  N N   . LEU A 42  ? 0.37485 0.36431 0.39372 -0.00273 -0.01032 -0.02139 42  LEU A N   
309  C CA  . LEU A 42  ? 0.35592 0.34365 0.36492 -0.00046 -0.00877 -0.01719 42  LEU A CA  
310  C C   . LEU A 42  ? 0.39535 0.37566 0.40347 0.00101  -0.00658 -0.01391 42  LEU A C   
311  O O   . LEU A 42  ? 0.38026 0.35714 0.38266 0.00327  -0.00446 -0.00917 42  LEU A O   
312  C CB  . LEU A 42  ? 0.37810 0.36969 0.38106 0.00119  -0.01124 -0.01976 42  LEU A CB  
313  C CG  . LEU A 42  ? 0.42949 0.41976 0.42579 0.00304  -0.01122 -0.01659 42  LEU A CG  
314  C CD1 . LEU A 42  ? 0.37503 0.36474 0.36701 0.00334  -0.01035 -0.01308 42  LEU A CD1 
315  C CD2 . LEU A 42  ? 0.40890 0.40406 0.40371 0.00426  -0.01260 -0.01829 42  LEU A CD2 
316  N N   . PHE A 43  ? 0.37661 0.35376 0.38934 0.00070  -0.00723 -0.01654 43  PHE A N   
317  C CA  . PHE A 43  ? 0.37812 0.34795 0.39022 0.00263  -0.00498 -0.01355 43  PHE A CA  
318  C C   . PHE A 43  ? 0.41100 0.37609 0.43429 0.00064  -0.00213 -0.01234 43  PHE A C   
319  O O   . PHE A 43  ? 0.40010 0.36738 0.43318 -0.00257 -0.00414 -0.01659 43  PHE A O   
320  C CB  . PHE A 43  ? 0.37916 0.34838 0.38805 0.00449  -0.00746 -0.01678 43  PHE A CB  
321  C CG  . PHE A 43  ? 0.39348 0.36742 0.39514 0.00626  -0.00960 -0.01677 43  PHE A CG  
322  C CD1 . PHE A 43  ? 0.40749 0.37898 0.40325 0.00891  -0.00970 -0.01323 43  PHE A CD1 
323  C CD2 . PHE A 43  ? 0.39562 0.37617 0.39708 0.00583  -0.01165 -0.02017 43  PHE A CD2 
324  C CE1 . PHE A 43  ? 0.40924 0.38491 0.40194 0.00988  -0.01244 -0.01350 43  PHE A CE1 
325  C CE2 . PHE A 43  ? 0.38954 0.37437 0.38746 0.00714  -0.01275 -0.01905 43  PHE A CE2 
326  C CZ  . PHE A 43  ? 0.37410 0.35654 0.36912 0.00852  -0.01344 -0.01591 43  PHE A CZ  
327  N N   . GLU A 44  ? 0.38511 0.34344 0.40745 0.00310  0.00244  -0.00633 44  GLU A N   
328  C CA  . GLU A 44  ? 0.42928 0.38202 0.46396 0.00160  0.00662  -0.00336 44  GLU A CA  
329  C C   . GLU A 44  ? 0.45952 0.40816 0.50098 0.00015  0.00409  -0.00850 44  GLU A C   
330  O O   . GLU A 44  ? 0.42582 0.37090 0.48183 -0.00290 0.00531  -0.00885 44  GLU A O   
331  C CB  . GLU A 44  ? 0.47465 0.42066 0.50388 0.00658  0.01312  0.00542  44  GLU A CB  
332  C CG  . GLU A 44  ? 0.54972 0.48871 0.59203 0.00614  0.01947  0.01083  44  GLU A CG  
333  C CD  . GLU A 44  ? 0.60107 0.54343 0.66035 0.00156  0.02233  0.01301  44  GLU A CD  
334  O OE1 . GLU A 44  ? 0.66160 0.61174 0.72028 -0.00043 0.01978  0.01087  44  GLU A OE1 
335  O OE2 . GLU A 44  ? 0.67716 0.61441 0.75185 -0.00001 0.02724  0.01718  44  GLU A OE2 
336  N N   . ALA A 45  ? 0.42568 0.37462 0.45809 0.00247  0.00056  -0.01243 45  ALA A N   
337  C CA  . ALA A 45  ? 0.42619 0.37090 0.46261 0.00242  -0.00189 -0.01751 45  ALA A CA  
338  C C   . ALA A 45  ? 0.47706 0.42659 0.50342 0.00494  -0.00610 -0.02215 45  ALA A C   
339  O O   . ALA A 45  ? 0.43560 0.38956 0.45305 0.00693  -0.00620 -0.01983 45  ALA A O   
340  C CB  . ALA A 45  ? 0.45755 0.39260 0.49532 0.00499  0.00259  -0.01266 45  ALA A CB  
341  N N   . TRP A 46  ? 0.43836 0.38675 0.46701 0.00531  -0.00957 -0.02862 46  TRP A N   
342  C CA  . TRP A 46  ? 0.41107 0.36363 0.43101 0.00896  -0.01214 -0.03194 46  TRP A CA  
343  C C   . TRP A 46  ? 0.44468 0.39117 0.46645 0.01118  -0.01409 -0.03706 46  TRP A C   
344  O O   . TRP A 46  ? 0.43545 0.37869 0.46447 0.00941  -0.01705 -0.04251 46  TRP A O   
345  C CB  . TRP A 46  ? 0.39230 0.35379 0.40901 0.00877  -0.01497 -0.03537 46  TRP A CB  
346  C CG  . TRP A 46  ? 0.39588 0.36342 0.40423 0.01270  -0.01517 -0.03498 46  TRP A CG  
347  C CD1 . TRP A 46  ? 0.42421 0.39336 0.42868 0.01705  -0.01662 -0.03893 46  TRP A CD1 
348  C CD2 . TRP A 46  ? 0.38841 0.36121 0.39285 0.01297  -0.01370 -0.03003 46  TRP A CD2 
349  N NE1 . TRP A 46  ? 0.37715 0.35303 0.37718 0.01970  -0.01507 -0.03560 46  TRP A NE1 
350  C CE2 . TRP A 46  ? 0.39129 0.36933 0.39227 0.01673  -0.01386 -0.03058 46  TRP A CE2 
351  C CE3 . TRP A 46  ? 0.40858 0.38173 0.41242 0.01095  -0.01247 -0.02531 46  TRP A CE3 
352  C CZ2 . TRP A 46  ? 0.43454 0.41840 0.43460 0.01735  -0.01306 -0.02649 46  TRP A CZ2 
353  C CZ3 . TRP A 46  ? 0.40125 0.37921 0.40195 0.01205  -0.01278 -0.02246 46  TRP A CZ3 
354  C CH2 . TRP A 46  ? 0.41226 0.39566 0.41261 0.01463  -0.01319 -0.02304 46  TRP A CH2 
355  N N   . ILE A 47  ? 0.43050 0.37535 0.44628 0.01536  -0.01302 -0.03568 47  ILE A N   
356  C CA  . ILE A 47  ? 0.42836 0.36690 0.44397 0.01869  -0.01442 -0.04004 47  ILE A CA  
357  C C   . ILE A 47  ? 0.43851 0.38299 0.44570 0.02409  -0.01582 -0.04265 47  ILE A C   
358  O O   . ILE A 47  ? 0.45442 0.39434 0.45914 0.02842  -0.01667 -0.04595 47  ILE A O   
359  C CB  . ILE A 47  ? 0.41287 0.34270 0.42984 0.02004  -0.01097 -0.03552 47  ILE A CB  
360  C CG1 . ILE A 47  ? 0.47937 0.41364 0.48913 0.02303  -0.00870 -0.02953 47  ILE A CG1 
361  C CG2 . ILE A 47  ? 0.41656 0.33948 0.44339 0.01569  -0.00831 -0.03230 47  ILE A CG2 
362  C CD1 . ILE A 47  ? 0.55296 0.47975 0.56093 0.02696  -0.00625 -0.02627 47  ILE A CD1 
363  N N   . GLY A 48  ? 0.43073 0.38503 0.43401 0.02438  -0.01554 -0.04075 48  GLY A N   
364  C CA  . GLY A 48  ? 0.43607 0.39711 0.43323 0.02978  -0.01548 -0.04171 48  GLY A CA  
365  C C   . GLY A 48  ? 0.46146 0.43121 0.45813 0.02958  -0.01320 -0.03553 48  GLY A C   
366  O O   . GLY A 48  ? 0.43686 0.40582 0.43587 0.02697  -0.01237 -0.03111 48  GLY A O   
367  N N   . ASP A 49  ? 0.41545 0.39325 0.40928 0.03310  -0.01227 -0.03519 49  ASP A N   
368  C CA  . ASP A 49  ? 0.46122 0.44755 0.45768 0.03251  -0.01035 -0.02947 49  ASP A CA  
369  C C   . ASP A 49  ? 0.47472 0.46256 0.47467 0.03470  -0.00920 -0.02546 49  ASP A C   
370  O O   . ASP A 49  ? 0.47522 0.46903 0.48024 0.03327  -0.00898 -0.02111 49  ASP A O   
371  C CB  . ASP A 49  ? 0.41392 0.40821 0.40786 0.03643  -0.00837 -0.02903 49  ASP A CB  
372  C CG  . ASP A 49  ? 0.47630 0.47107 0.46687 0.03464  -0.00993 -0.03234 49  ASP A CG  
373  O OD1 . ASP A 49  ? 0.46193 0.45214 0.45422 0.02937  -0.01240 -0.03433 49  ASP A OD1 
374  O OD2 . ASP A 49  ? 0.45840 0.45855 0.44475 0.03927  -0.00825 -0.03238 49  ASP A OD2 
375  N N   . ASP A 50  ? 0.43195 0.41464 0.43013 0.03840  -0.00898 -0.02710 50  ASP A N   
376  C CA  . ASP A 50  ? 0.42826 0.41254 0.42996 0.04098  -0.00831 -0.02348 50  ASP A CA  
377  C C   . ASP A 50  ? 0.45314 0.43122 0.45575 0.03810  -0.01018 -0.02206 50  ASP A C   
378  O O   . ASP A 50  ? 0.44714 0.42592 0.45199 0.04069  -0.01061 -0.01954 50  ASP A O   
379  C CB  . ASP A 50  ? 0.43368 0.41536 0.43197 0.04760  -0.00676 -0.02544 50  ASP A CB  
380  C CG  . ASP A 50  ? 0.51492 0.48477 0.50808 0.04761  -0.00830 -0.03100 50  ASP A CG  
381  O OD1 . ASP A 50  ? 0.48125 0.44694 0.47422 0.04291  -0.01009 -0.03381 50  ASP A OD1 
382  O OD2 . ASP A 50  ? 0.52286 0.48757 0.51344 0.05242  -0.00775 -0.03253 50  ASP A OD2 
383  N N   . ASP A 51  ? 0.41988 0.39232 0.42074 0.03371  -0.01106 -0.02321 51  ASP A N   
384  C CA  . ASP A 51  ? 0.42722 0.39363 0.42732 0.03229  -0.01172 -0.02082 51  ASP A CA  
385  C C   . ASP A 51  ? 0.44928 0.42167 0.45146 0.03229  -0.01392 -0.01743 51  ASP A C   
386  O O   . ASP A 51  ? 0.41143 0.38972 0.41578 0.02947  -0.01486 -0.01696 51  ASP A O   
387  C CB  . ASP A 51  ? 0.43599 0.39716 0.43538 0.02787  -0.01120 -0.02185 51  ASP A CB  
388  C CG  . ASP A 51  ? 0.47926 0.43313 0.47686 0.02776  -0.01019 -0.01836 51  ASP A CG  
389  O OD1 . ASP A 51  ? 0.43498 0.38825 0.43008 0.03125  -0.01096 -0.01556 51  ASP A OD1 
390  O OD2 . ASP A 51  ? 0.47843 0.42734 0.47742 0.02479  -0.00851 -0.01820 51  ASP A OD2 
391  N N   . PRO A 52  ? 0.46034 0.43125 0.46231 0.03578  -0.01541 -0.01545 52  PRO A N   
392  C CA  . PRO A 52  ? 0.45000 0.42636 0.45520 0.03628  -0.01939 -0.01356 52  PRO A CA  
393  C C   . PRO A 52  ? 0.48695 0.45856 0.48681 0.03523  -0.02152 -0.01268 52  PRO A C   
394  O O   . PRO A 52  ? 0.44452 0.41864 0.44566 0.03677  -0.02621 -0.01216 52  PRO A O   
395  C CB  . PRO A 52  ? 0.43710 0.41336 0.44354 0.04170  -0.02086 -0.01259 52  PRO A CB  
396  C CG  . PRO A 52  ? 0.51298 0.47925 0.51270 0.04388  -0.01742 -0.01294 52  PRO A CG  
397  C CD  . PRO A 52  ? 0.46141 0.42604 0.46092 0.04016  -0.01411 -0.01535 52  PRO A CD  
398  N N   . ASN A 53  ? 0.42361 0.38840 0.41816 0.03327  -0.01847 -0.01254 53  ASN A N   
399  C CA  . ASN A 53  ? 0.42915 0.38953 0.41788 0.03311  -0.01903 -0.01086 53  ASN A CA  
400  C C   . ASN A 53  ? 0.42254 0.38919 0.41338 0.03151  -0.02351 -0.01147 53  ASN A C   
401  O O   . ASN A 53  ? 0.41139 0.38391 0.40715 0.02726  -0.02297 -0.01253 53  ASN A O   
402  C CB  . ASN A 53  ? 0.43468 0.39088 0.42265 0.02944  -0.01458 -0.01059 53  ASN A CB  
403  C CG  . ASN A 53  ? 0.50994 0.46116 0.49173 0.03047  -0.01346 -0.00755 53  ASN A CG  
404  O OD1 . ASN A 53  ? 0.47510 0.42627 0.45151 0.03379  -0.01690 -0.00664 53  ASN A OD1 
405  N ND2 . ASN A 53  ? 0.48733 0.43429 0.47049 0.02813  -0.00883 -0.00605 53  ASN A ND2 
406  N N   . PRO A 54  ? 0.42257 0.38765 0.40976 0.03543  -0.02839 -0.01109 54  PRO A N   
407  C CA  . PRO A 54  ? 0.42677 0.39691 0.41792 0.03385  -0.03386 -0.01244 54  PRO A CA  
408  C C   . PRO A 54  ? 0.43722 0.40673 0.42547 0.03011  -0.03224 -0.01223 54  PRO A C   
409  O O   . PRO A 54  ? 0.39930 0.37422 0.39378 0.02692  -0.03477 -0.01318 54  PRO A O   
410  C CB  . PRO A 54  ? 0.45207 0.41785 0.43708 0.04038  -0.04024 -0.01308 54  PRO A CB  
411  C CG  . PRO A 54  ? 0.46419 0.42650 0.44607 0.04520  -0.03828 -0.01190 54  PRO A CG  
412  C CD  . PRO A 54  ? 0.47623 0.43492 0.45614 0.04236  -0.02992 -0.00990 54  PRO A CD  
413  N N   . LEU A 55  ? 0.41212 0.37538 0.39242 0.03055  -0.02770 -0.01047 55  LEU A N   
414  C CA  . LEU A 55  ? 0.44064 0.40428 0.41921 0.02709  -0.02565 -0.01000 55  LEU A CA  
415  C C   . LEU A 55  ? 0.43031 0.40161 0.41745 0.02142  -0.02406 -0.01147 55  LEU A C   
416  O O   . LEU A 55  ? 0.40109 0.37559 0.38938 0.01884  -0.02494 -0.01179 55  LEU A O   
417  C CB  . LEU A 55  ? 0.42237 0.37960 0.39530 0.02801  -0.01983 -0.00712 55  LEU A CB  
418  C CG  . LEU A 55  ? 0.47152 0.42983 0.44415 0.02456  -0.01695 -0.00620 55  LEU A CG  
419  C CD1 . LEU A 55  ? 0.48474 0.44154 0.44998 0.02731  -0.02037 -0.00580 55  LEU A CD1 
420  C CD2 . LEU A 55  ? 0.45022 0.40359 0.42270 0.02468  -0.01058 -0.00286 55  LEU A CD2 
421  N N   . HIS A 56  ? 0.39808 0.37187 0.39015 0.02048  -0.02167 -0.01234 56  HIS A N   
422  C CA  . HIS A 56  ? 0.39568 0.37624 0.39343 0.01722  -0.01991 -0.01369 56  HIS A CA  
423  C C   . HIS A 56  ? 0.40050 0.38801 0.40468 0.01651  -0.02254 -0.01322 56  HIS A C   
424  O O   . HIS A 56  ? 0.42258 0.41448 0.42893 0.01414  -0.02134 -0.01302 56  HIS A O   
425  C CB  . HIS A 56  ? 0.41608 0.39687 0.41608 0.01827  -0.01750 -0.01511 56  HIS A CB  
426  C CG  . HIS A 56  ? 0.41158 0.38533 0.40870 0.01803  -0.01493 -0.01583 56  HIS A CG  
427  N ND1 . HIS A 56  ? 0.43104 0.40274 0.42977 0.01896  -0.01340 -0.01803 56  HIS A ND1 
428  C CD2 . HIS A 56  ? 0.44898 0.41703 0.44317 0.01718  -0.01338 -0.01427 56  HIS A CD2 
429  C CE1 . HIS A 56  ? 0.43594 0.40074 0.43454 0.01789  -0.01151 -0.01810 56  HIS A CE1 
430  N NE2 . HIS A 56  ? 0.44237 0.40535 0.43880 0.01682  -0.01089 -0.01524 56  HIS A NE2 
431  N N   . GLN A 57  ? 0.39543 0.38411 0.40401 0.01873  -0.02618 -0.01279 57  GLN A N   
432  C CA  . GLN A 57  ? 0.44645 0.44191 0.46538 0.01755  -0.02881 -0.01189 57  GLN A CA  
433  C C   . GLN A 57  ? 0.41616 0.40949 0.43380 0.01601  -0.03266 -0.01222 57  GLN A C   
434  O O   . GLN A 57  ? 0.42797 0.42603 0.45328 0.01349  -0.03269 -0.01113 57  GLN A O   
435  C CB  . GLN A 57  ? 0.46365 0.46158 0.49038 0.02026  -0.03253 -0.01170 57  GLN A CB  
436  C CG  . GLN A 57  ? 0.56873 0.56665 0.59410 0.02299  -0.02915 -0.01156 57  GLN A CG  
437  C CD  . GLN A 57  ? 0.74161 0.74577 0.77139 0.02239  -0.02350 -0.01032 57  GLN A CD  
438  O OE1 . GLN A 57  ? 0.73074 0.73202 0.75348 0.02300  -0.01970 -0.01162 57  GLN A OE1 
439  N NE2 . GLN A 57  ? 0.83697 0.84944 0.87884 0.02182  -0.02300 -0.00772 57  GLN A NE2 
440  N N   . GLN A 58  ? 0.42503 0.41074 0.43273 0.01836  -0.03564 -0.01335 58  GLN A N   
441  C CA  . GLN A 58  ? 0.43811 0.42036 0.44180 0.01820  -0.03938 -0.01409 58  GLN A CA  
442  C C   . GLN A 58  ? 0.43236 0.41619 0.43389 0.01472  -0.03471 -0.01301 58  GLN A C   
443  O O   . GLN A 58  ? 0.42825 0.41346 0.43319 0.01285  -0.03655 -0.01296 58  GLN A O   
444  C CB  . GLN A 58  ? 0.49212 0.46542 0.48260 0.02343  -0.04198 -0.01481 58  GLN A CB  
445  C CG  . GLN A 58  ? 0.54842 0.51979 0.53952 0.02831  -0.04805 -0.01643 58  GLN A CG  
446  C CD  . GLN A 58  ? 0.59977 0.56212 0.57558 0.03531  -0.04824 -0.01593 58  GLN A CD  
447  O OE1 . GLN A 58  ? 0.69094 0.64882 0.65739 0.03606  -0.04267 -0.01354 58  GLN A OE1 
448  N NE2 . GLN A 58  ? 0.60368 0.56366 0.57757 0.04111  -0.05441 -0.01774 58  GLN A NE2 
449  N N   . ILE A 59  ? 0.40170 0.38518 0.39848 0.01396  -0.02911 -0.01236 59  ILE A N   
450  C CA  . ILE A 59  ? 0.40326 0.38902 0.39848 0.01120  -0.02540 -0.01186 59  ILE A CA  
451  C C   . ILE A 59  ? 0.41371 0.40722 0.41740 0.00907  -0.02357 -0.01128 59  ILE A C   
452  O O   . ILE A 59  ? 0.38273 0.37849 0.38710 0.00755  -0.02276 -0.01044 59  ILE A O   
453  C CB  . ILE A 59  ? 0.43232 0.41590 0.42308 0.01097  -0.02108 -0.01196 59  ILE A CB  
454  C CG1 . ILE A 59  ? 0.42870 0.40475 0.41141 0.01367  -0.02103 -0.01058 59  ILE A CG1 
455  C CG2 . ILE A 59  ? 0.40513 0.39282 0.39633 0.00838  -0.01817 -0.01232 59  ILE A CG2 
456  C CD1 . ILE A 59  ? 0.41171 0.38524 0.38843 0.01492  -0.02311 -0.00976 59  ILE A CD1 
457  N N   . ALA A 60  ? 0.38368 0.38116 0.39328 0.00987  -0.02221 -0.01112 60  ALA A N   
458  C CA  . ALA A 60  ? 0.40137 0.40628 0.41831 0.00958  -0.01916 -0.00934 60  ALA A CA  
459  C C   . ALA A 60  ? 0.41417 0.42160 0.44027 0.00820  -0.02139 -0.00705 60  ALA A C   
460  O O   . ALA A 60  ? 0.39146 0.40271 0.42059 0.00741  -0.01839 -0.00482 60  ALA A O   
461  C CB  . ALA A 60  ? 0.36466 0.37295 0.38594 0.01201  -0.01719 -0.00904 60  ALA A CB  
462  N N   . SER A 61  ? 0.39626 0.40117 0.42731 0.00829  -0.02703 -0.00775 61  SER A N   
463  C CA  . SER A 61  ? 0.44009 0.44643 0.48249 0.00659  -0.03072 -0.00649 61  SER A CA  
464  C C   . SER A 61  ? 0.41945 0.42139 0.45561 0.00517  -0.03192 -0.00709 61  SER A C   
465  O O   . SER A 61  ? 0.42864 0.43271 0.47354 0.00331  -0.03158 -0.00493 61  SER A O   
466  C CB  . SER A 61  ? 0.46280 0.46663 0.51107 0.00776  -0.03850 -0.00870 61  SER A CB  
467  O OG  . SER A 61  ? 0.67123 0.68060 0.72849 0.00905  -0.03727 -0.00738 61  SER A OG  
468  N N   . ALA A 62  ? 0.45940 0.45506 0.48121 0.00641  -0.03280 -0.00938 62  ALA A N   
469  C CA  . ALA A 62  ? 0.46825 0.45964 0.48316 0.00597  -0.03372 -0.00975 62  ALA A CA  
470  C C   . ALA A 62  ? 0.43319 0.42931 0.44747 0.00440  -0.02738 -0.00741 62  ALA A C   
471  O O   . ALA A 62  ? 0.39869 0.39439 0.41473 0.00339  -0.02739 -0.00617 62  ALA A O   
472  C CB  . ALA A 62  ? 0.43797 0.42220 0.43837 0.00874  -0.03499 -0.01157 62  ALA A CB  
473  N N   . ILE A 63  ? 0.40299 0.40301 0.41421 0.00484  -0.02246 -0.00718 63  ILE A N   
474  C CA  . ILE A 63  ? 0.43381 0.43878 0.44371 0.00480  -0.01729 -0.00565 63  ILE A CA  
475  C C   . ILE A 63  ? 0.40241 0.41291 0.42322 0.00488  -0.01462 -0.00192 63  ILE A C   
476  O O   . ILE A 63  ? 0.39790 0.41037 0.41905 0.00505  -0.01170 0.00052  63  ILE A O   
477  C CB  . ILE A 63  ? 0.41439 0.42150 0.41908 0.00606  -0.01432 -0.00753 63  ILE A CB  
478  C CG1 . ILE A 63  ? 0.38637 0.38825 0.38319 0.00556  -0.01570 -0.00983 63  ILE A CG1 
479  C CG2 . ILE A 63  ? 0.39438 0.40705 0.39728 0.00768  -0.01005 -0.00671 63  ILE A CG2 
480  C CD1 . ILE A 63  ? 0.40154 0.40423 0.39642 0.00608  -0.01393 -0.01225 63  ILE A CD1 
481  N N   . LYS A 64  ? 0.37455 0.38786 0.40520 0.00523  -0.01495 -0.00068 64  LYS A N   
482  C CA  . LYS A 64  ? 0.41896 0.43829 0.46277 0.00569  -0.01116 0.00431  64  LYS A CA  
483  C C   . LYS A 64  ? 0.41665 0.43376 0.46940 0.00310  -0.01352 0.00639  64  LYS A C   
484  O O   . LYS A 64  ? 0.38261 0.40358 0.44307 0.00356  -0.00846 0.01142  64  LYS A O   
485  C CB  . LYS A 64  ? 0.40042 0.42339 0.45501 0.00651  -0.01158 0.00544  64  LYS A CB  
486  C CG  . LYS A 64  ? 0.47014 0.50061 0.54077 0.00767  -0.00615 0.01203  64  LYS A CG  
487  C CD  . LYS A 64  ? 0.47523 0.51074 0.53882 0.01253  0.00252  0.01530  64  LYS A CD  
488  C CE  . LYS A 64  ? 0.55140 0.59483 0.62941 0.01586  0.00922  0.02247  64  LYS A CE  
489  N NZ  . LYS A 64  ? 0.55393 0.59967 0.64931 0.01363  0.01161  0.02894  64  LYS A NZ  
490  N N   . ALA A 65  ? 0.37521 0.38540 0.42647 0.00120  -0.02107 0.00266  65  ALA A N   
491  C CA  . ALA A 65  ? 0.45010 0.45633 0.50877 -0.00088 -0.02472 0.00330  65  ALA A CA  
492  C C   . ALA A 65  ? 0.44833 0.45317 0.49795 -0.00045 -0.02063 0.00483  65  ALA A C   
493  O O   . ALA A 65  ? 0.40614 0.41038 0.46465 -0.00162 -0.01956 0.00802  65  ALA A O   
494  C CB  . ALA A 65  ? 0.47282 0.47080 0.52788 -0.00104 -0.03455 -0.00216 65  ALA A CB  
495  N N   . VAL A 66  ? 0.40562 0.40997 0.43908 0.00127  -0.01840 0.00277  66  VAL A N   
496  C CA  . VAL A 66  ? 0.39121 0.39571 0.41629 0.00230  -0.01445 0.00417  66  VAL A CA  
497  C C   . VAL A 66  ? 0.43406 0.44592 0.46391 0.00429  -0.00676 0.00921  66  VAL A C   
498  O O   . VAL A 66  ? 0.40158 0.41368 0.43300 0.00503  -0.00339 0.01281  66  VAL A O   
499  C CB  . VAL A 66  ? 0.45056 0.45372 0.46032 0.00355  -0.01448 0.00069  66  VAL A CB  
500  C CG1 . VAL A 66  ? 0.41731 0.42263 0.41983 0.00510  -0.01040 0.00208  66  VAL A CG1 
501  C CG2 . VAL A 66  ? 0.43248 0.42777 0.43598 0.00329  -0.02053 -0.00267 66  VAL A CG2 
502  N N   . VAL A 67  ? 0.40414 0.42153 0.43534 0.00622  -0.00358 0.00979  67  VAL A N   
503  C CA  . VAL A 67  ? 0.41040 0.43461 0.44389 0.01027  0.00414  0.01476  67  VAL A CA  
504  C C   . VAL A 67  ? 0.43421 0.46012 0.48470 0.00952  0.00743  0.02157  67  VAL A C   
505  O O   . VAL A 67  ? 0.41171 0.44024 0.46322 0.01255  0.01398  0.02706  67  VAL A O   
506  C CB  . VAL A 67  ? 0.43134 0.45982 0.46270 0.01321  0.00592  0.01345  67  VAL A CB  
507  C CG1 . VAL A 67  ? 0.40782 0.44311 0.44212 0.01906  0.01422  0.01944  67  VAL A CG1 
508  C CG2 . VAL A 67  ? 0.38420 0.41088 0.40084 0.01401  0.00326  0.00708  67  VAL A CG2 
509  N N   . ASP A 68  ? 0.38374 0.40819 0.44892 0.00580  0.00290  0.02152  68  ASP A N   
510  C CA  . ASP A 68  ? 0.39437 0.42048 0.48058 0.00409  0.00507  0.02784  68  ASP A CA  
511  C C   . ASP A 68  ? 0.44655 0.46671 0.53515 0.00182  0.00349  0.02884  68  ASP A C   
512  O O   . ASP A 68  ? 0.47126 0.49277 0.57623 0.00126  0.00784  0.03557  68  ASP A O   
513  C CB  . ASP A 68  ? 0.39707 0.42295 0.49949 0.00051  -0.00160 0.02603  68  ASP A CB  
514  C CG  . ASP A 68  ? 0.49157 0.52413 0.59570 0.00320  0.00132  0.02689  68  ASP A CG  
515  O OD1 . ASP A 68  ? 0.46738 0.50544 0.56496 0.00821  0.00978  0.03072  68  ASP A OD1 
516  O OD2 . ASP A 68  ? 0.45616 0.48816 0.56768 0.00114  -0.00518 0.02358  68  ASP A OD2 
517  N N   . ALA A 69  ? 0.43692 0.45029 0.51046 0.00083  -0.00219 0.02281  69  ALA A N   
518  C CA  . ALA A 69  ? 0.46869 0.47578 0.54102 -0.00020 -0.00343 0.02334  69  ALA A CA  
519  C C   . ALA A 69  ? 0.45696 0.46712 0.51938 0.00395  0.00514  0.02782  69  ALA A C   
520  O O   . ALA A 69  ? 0.50543 0.51054 0.56431 0.00392  0.00494  0.02845  69  ALA A O   
521  C CB  . ALA A 69  ? 0.45940 0.45818 0.51829 -0.00138 -0.01219 0.01573  69  ALA A CB  
522  N N   . GLY A 70  ? 0.43887 0.45667 0.49560 0.00840  0.01211  0.03050  70  GLY A N   
523  C CA  . GLY A 70  ? 0.43806 0.45927 0.48476 0.01400  0.01984  0.03456  70  GLY A CA  
524  C C   . GLY A 70  ? 0.44526 0.46701 0.47121 0.01675  0.01817  0.02888  70  GLY A C   
525  O O   . GLY A 70  ? 0.44659 0.47075 0.46334 0.02178  0.02309  0.03128  70  GLY A O   
526  N N   . VAL A 71  ? 0.42328 0.44317 0.44266 0.01406  0.01163  0.02185  71  VAL A N   
527  C CA  . VAL A 71  ? 0.39623 0.41688 0.39996 0.01577  0.00971  0.01661  71  VAL A CA  
528  C C   . VAL A 71  ? 0.39766 0.42347 0.39738 0.01847  0.01054  0.01393  71  VAL A C   
529  O O   . VAL A 71  ? 0.37669 0.40122 0.38000 0.01568  0.00702  0.01100  71  VAL A O   
530  C CB  . VAL A 71  ? 0.43653 0.45079 0.43615 0.01162  0.00279  0.01157  71  VAL A CB  
531  C CG1 . VAL A 71  ? 0.42056 0.43678 0.40772 0.01315  0.00170  0.00722  71  VAL A CG1 
532  C CG2 . VAL A 71  ? 0.46788 0.47575 0.47014 0.01001  0.00120  0.01345  71  VAL A CG2 
533  N N   . PRO A 72  ? 0.39691 0.42790 0.38838 0.02461  0.01458  0.01438  72  PRO A N   
534  C CA  . PRO A 72  ? 0.43858 0.47312 0.42510 0.02789  0.01412  0.01053  72  PRO A CA  
535  C C   . PRO A 72  ? 0.43274 0.46490 0.41435 0.02431  0.00767  0.00309  72  PRO A C   
536  O O   . PRO A 72  ? 0.38491 0.41585 0.36169 0.02288  0.00523  0.00078  72  PRO A O   
537  C CB  . PRO A 72  ? 0.45753 0.49705 0.43416 0.03659  0.01871  0.01194  72  PRO A CB  
538  C CG  . PRO A 72  ? 0.42707 0.46544 0.40053 0.03657  0.01966  0.01419  72  PRO A CG  
539  C CD  . PRO A 72  ? 0.41605 0.44920 0.40110 0.02975  0.01909  0.01784  72  PRO A CD  
540  N N   . CYS A 73  ? 0.36315 0.39474 0.34698 0.02322  0.00556  0.00004  73  CYS A N   
541  C CA  . CYS A 73  ? 0.37897 0.40760 0.36090 0.01969  0.00043  -0.00582 73  CYS A CA  
542  C C   . CYS A 73  ? 0.42700 0.45800 0.40425 0.02367  -0.00062 -0.01071 73  CYS A C   
543  O O   . CYS A 73  ? 0.40246 0.43547 0.37970 0.02788  0.00186  -0.00967 73  CYS A O   
544  C CB  . CYS A 73  ? 0.37940 0.40336 0.36825 0.01489  -0.00195 -0.00545 73  CYS A CB  
545  S SG  . CYS A 73  ? 0.42629 0.44513 0.41871 0.01070  -0.00380 -0.00251 73  CYS A SG  
546  N N   . TYR A 74  ? 0.38938 0.41997 0.36360 0.02265  -0.00449 -0.01606 74  TYR A N   
547  C CA  . TYR A 74  ? 0.42998 0.46206 0.40047 0.02653  -0.00721 -0.02217 74  TYR A CA  
548  C C   . TYR A 74  ? 0.41630 0.44435 0.39192 0.02150  -0.01155 -0.02680 74  TYR A C   
549  O O   . TYR A 74  ? 0.40061 0.42626 0.38029 0.01629  -0.01223 -0.02548 74  TYR A O   
550  C CB  . TYR A 74  ? 0.41503 0.45163 0.37863 0.03164  -0.00843 -0.02492 74  TYR A CB  
551  C CG  . TYR A 74  ? 0.41871 0.45895 0.37637 0.03774  -0.00314 -0.01947 74  TYR A CG  
552  C CD1 . TYR A 74  ? 0.40420 0.44463 0.36303 0.03546  -0.00038 -0.01421 74  TYR A CD1 
553  C CD2 . TYR A 74  ? 0.41436 0.45725 0.36488 0.04665  -0.00047 -0.01920 74  TYR A CD2 
554  C CE1 . TYR A 74  ? 0.43701 0.48003 0.39188 0.04096  0.00514  -0.00844 74  TYR A CE1 
555  C CE2 . TYR A 74  ? 0.45066 0.49675 0.39631 0.05307  0.00585  -0.01271 74  TYR A CE2 
556  C CZ  . TYR A 74  ? 0.44265 0.48872 0.39141 0.04972  0.00871  -0.00720 74  TYR A CZ  
557  O OH  . TYR A 74  ? 0.47523 0.52370 0.42067 0.05587  0.01557  -0.00003 74  TYR A OH  
558  N N   . PHE A 75  ? 0.40135 0.42826 0.37653 0.02392  -0.01415 -0.03200 75  PHE A N   
559  C CA  . PHE A 75  ? 0.39289 0.41507 0.37465 0.01941  -0.01753 -0.03577 75  PHE A CA  
560  C C   . PHE A 75  ? 0.41101 0.43345 0.39260 0.02241  -0.02286 -0.04393 75  PHE A C   
561  O O   . PHE A 75  ? 0.41450 0.43793 0.38916 0.02922  -0.02387 -0.04732 75  PHE A O   
562  C CB  . PHE A 75  ? 0.39373 0.41154 0.37781 0.01826  -0.01584 -0.03371 75  PHE A CB  
563  C CG  . PHE A 75  ? 0.41851 0.43046 0.40922 0.01398  -0.01808 -0.03611 75  PHE A CG  
564  C CD1 . PHE A 75  ? 0.42935 0.43843 0.42486 0.00884  -0.01712 -0.03271 75  PHE A CD1 
565  C CD2 . PHE A 75  ? 0.40931 0.41798 0.40099 0.01597  -0.02072 -0.04138 75  PHE A CD2 
566  C CE1 . PHE A 75  ? 0.42024 0.42370 0.42212 0.00580  -0.01778 -0.03352 75  PHE A CE1 
567  C CE2 . PHE A 75  ? 0.40299 0.40552 0.40206 0.01207  -0.02207 -0.04284 75  PHE A CE2 
568  C CZ  . PHE A 75  ? 0.38369 0.38384 0.38823 0.00699  -0.02010 -0.03838 75  PHE A CZ  
569  N N   . ILE A 76  ? 0.37529 0.39679 0.36507 0.01794  -0.02638 -0.04703 76  ILE A N   
570  C CA  . ILE A 76  ? 0.40184 0.42187 0.39682 0.01872  -0.03280 -0.05542 76  ILE A CA  
571  C C   . ILE A 76  ? 0.42852 0.44184 0.43439 0.01273  -0.03273 -0.05502 76  ILE A C   
572  O O   . ILE A 76  ? 0.41053 0.42251 0.42215 0.00746  -0.02910 -0.04919 76  ILE A O   
573  C CB  . ILE A 76  ? 0.40622 0.43140 0.40585 0.01834  -0.03714 -0.05912 76  ILE A CB  
574  C CG1 . ILE A 76  ? 0.39034 0.42153 0.37732 0.02634  -0.03786 -0.06058 76  ILE A CG1 
575  C CG2 . ILE A 76  ? 0.40562 0.42840 0.41683 0.01675  -0.04465 -0.06765 76  ILE A CG2 
576  C CD1 . ILE A 76  ? 0.39917 0.43603 0.38983 0.02748  -0.04344 -0.06549 76  ILE A CD1 
577  N N   . HIS A 77  ? 0.40828 0.41673 0.41595 0.01450  -0.03641 -0.06090 77  HIS A N   
578  C CA  . HIS A 77  ? 0.42612 0.42721 0.44361 0.00967  -0.03564 -0.06001 77  HIS A CA  
579  C C   . HIS A 77  ? 0.41216 0.41248 0.44571 0.00344  -0.03724 -0.06030 77  HIS A C   
580  O O   . HIS A 77  ? 0.41982 0.42431 0.45942 0.00337  -0.04230 -0.06533 77  HIS A O   
581  C CB  . HIS A 77  ? 0.41141 0.40682 0.42721 0.01361  -0.03975 -0.06696 77  HIS A CB  
582  C CG  . HIS A 77  ? 0.46750 0.46347 0.46943 0.02017  -0.03693 -0.06549 77  HIS A CG  
583  N ND1 . HIS A 77  ? 0.48563 0.48639 0.47572 0.02807  -0.03833 -0.06846 77  HIS A ND1 
584  C CD2 . HIS A 77  ? 0.44085 0.43371 0.43971 0.02061  -0.03238 -0.06075 77  HIS A CD2 
585  C CE1 . HIS A 77  ? 0.51487 0.51561 0.49636 0.03285  -0.03397 -0.06492 77  HIS A CE1 
586  N NE2 . HIS A 77  ? 0.47170 0.46801 0.45898 0.02812  -0.03081 -0.06060 77  HIS A NE2 
587  N N   . GLY A 78  ? 0.40359 0.39870 0.44472 -0.00118 -0.03268 -0.05445 78  GLY A N   
588  C CA  . GLY A 78  ? 0.41137 0.40463 0.46988 -0.00659 -0.03249 -0.05318 78  GLY A CA  
589  C C   . GLY A 78  ? 0.42540 0.41021 0.49489 -0.00826 -0.03482 -0.05699 78  GLY A C   
590  O O   . GLY A 78  ? 0.43669 0.41702 0.49895 -0.00478 -0.03724 -0.06147 78  GLY A O   
591  N N   . ASN A 79  ? 0.45041 0.43286 0.53861 -0.01341 -0.03352 -0.05456 79  ASN A N   
592  C CA  . ASN A 79  ? 0.47554 0.44891 0.57698 -0.01560 -0.03506 -0.05724 79  ASN A CA  
593  C C   . ASN A 79  ? 0.46627 0.43184 0.55989 -0.01427 -0.02851 -0.05092 79  ASN A C   
594  O O   . ASN A 79  ? 0.45548 0.41286 0.55285 -0.01382 -0.03038 -0.05447 79  ASN A O   
595  C CB  . ASN A 79  ? 0.48118 0.45438 0.60784 -0.02159 -0.03419 -0.05475 79  ASN A CB  
596  C CG  . ASN A 79  ? 0.48363 0.45865 0.61250 -0.02341 -0.02399 -0.04214 79  ASN A CG  
597  O OD1 . ASN A 79  ? 0.48793 0.47027 0.60715 -0.02200 -0.02180 -0.03868 79  ASN A OD1 
598  N ND2 . ASN A 79  ? 0.45525 0.42304 0.59635 -0.02569 -0.01752 -0.03508 79  ASN A ND2 
599  N N   . ARG A 80  ? 0.43066 0.39823 0.51311 -0.01302 -0.02160 -0.04225 80  ARG A N   
600  C CA  . ARG A 80  ? 0.47479 0.43559 0.54948 -0.01093 -0.01616 -0.03644 80  ARG A CA  
601  C C   . ARG A 80  ? 0.43880 0.40014 0.49669 -0.00622 -0.01837 -0.03980 80  ARG A C   
602  O O   . ARG A 80  ? 0.45012 0.40487 0.50522 -0.00418 -0.01744 -0.03977 80  ARG A O   
603  C CB  . ARG A 80  ? 0.42413 0.38596 0.49436 -0.01055 -0.00871 -0.02616 80  ARG A CB  
604  C CG  . ARG A 80  ? 0.44408 0.40654 0.52992 -0.01392 -0.00441 -0.02048 80  ARG A CG  
605  C CD  . ARG A 80  ? 0.48389 0.43799 0.58704 -0.01631 -0.00167 -0.01840 80  ARG A CD  
606  N NE  . ARG A 80  ? 0.50331 0.44914 0.59826 -0.01270 0.00411  -0.01217 80  ARG A NE  
607  C CZ  . ARG A 80  ? 0.58834 0.52590 0.69520 -0.01320 0.00969  -0.00656 80  ARG A CZ  
608  N NH1 . ARG A 80  ? 0.47918 0.41552 0.60937 -0.01798 0.01054  -0.00595 80  ARG A NH1 
609  N NH2 . ARG A 80  ? 0.52980 0.46020 0.62607 -0.00853 0.01452  -0.00121 80  ARG A NH2 
610  N N   . ASP A 81  ? 0.42408 0.39325 0.47161 -0.00409 -0.02065 -0.04198 81  ASP A N   
611  C CA  . ASP A 81  ? 0.45465 0.42570 0.48799 0.00045  -0.02077 -0.04250 81  ASP A CA  
612  C C   . ASP A 81  ? 0.41761 0.39218 0.44588 0.00420  -0.02615 -0.05052 81  ASP A C   
613  O O   . ASP A 81  ? 0.42643 0.40668 0.44425 0.00787  -0.02573 -0.05007 81  ASP A O   
614  C CB  . ASP A 81  ? 0.38523 0.36152 0.41004 0.00100  -0.01737 -0.03628 81  ASP A CB  
615  C CG  . ASP A 81  ? 0.43854 0.42116 0.46519 -0.00105 -0.01772 -0.03559 81  ASP A CG  
616  O OD1 . ASP A 81  ? 0.41736 0.40199 0.45155 -0.00252 -0.02115 -0.04040 81  ASP A OD1 
617  O OD2 . ASP A 81  ? 0.40865 0.39413 0.42921 -0.00077 -0.01514 -0.03061 81  ASP A OD2 
618  N N   . PHE A 82  ? 0.43286 0.40350 0.46865 0.00407  -0.03129 -0.05790 82  PHE A N   
619  C CA  . PHE A 82  ? 0.45326 0.42585 0.48214 0.00959  -0.03723 -0.06649 82  PHE A CA  
620  C C   . PHE A 82  ? 0.44624 0.41669 0.46306 0.01596  -0.03602 -0.06709 82  PHE A C   
621  O O   . PHE A 82  ? 0.44967 0.42246 0.45706 0.02263  -0.03931 -0.07256 82  PHE A O   
622  C CB  . PHE A 82  ? 0.46169 0.42922 0.50267 0.00822  -0.04459 -0.07542 82  PHE A CB  
623  C CG  . PHE A 82  ? 0.46273 0.41966 0.51376 0.00559  -0.04407 -0.07559 82  PHE A CG  
624  C CD1 . PHE A 82  ? 0.49511 0.44862 0.56163 -0.00121 -0.04012 -0.06967 82  PHE A CD1 
625  C CD2 . PHE A 82  ? 0.45331 0.40337 0.49810 0.01075  -0.04694 -0.08114 82  PHE A CD2 
626  C CE1 . PHE A 82  ? 0.46987 0.41306 0.54597 -0.00311 -0.03869 -0.06885 82  PHE A CE1 
627  C CE2 . PHE A 82  ? 0.46211 0.40164 0.51607 0.00860  -0.04626 -0.08111 82  PHE A CE2 
628  C CZ  . PHE A 82  ? 0.46499 0.40096 0.53494 0.00151  -0.04199 -0.07479 82  PHE A CZ  
629  N N   . LEU A 83  ? 0.40118 0.36754 0.41759 0.01514  -0.03129 -0.06145 83  LEU A N   
630  C CA  . LEU A 83  ? 0.40583 0.37156 0.41222 0.02140  -0.02978 -0.06134 83  LEU A CA  
631  C C   . LEU A 83  ? 0.44553 0.41965 0.44405 0.02357  -0.02521 -0.05481 83  LEU A C   
632  O O   . LEU A 83  ? 0.43091 0.40621 0.42322 0.02873  -0.02309 -0.05336 83  LEU A O   
633  C CB  . LEU A 83  ? 0.42780 0.38491 0.43802 0.02053  -0.02770 -0.05926 83  LEU A CB  
634  C CG  . LEU A 83  ? 0.46321 0.41024 0.48054 0.02036  -0.03222 -0.06639 83  LEU A CG  
635  C CD1 . LEU A 83  ? 0.43856 0.37712 0.45814 0.02042  -0.02891 -0.06296 83  LEU A CD1 
636  C CD2 . LEU A 83  ? 0.44156 0.38796 0.45090 0.02758  -0.03807 -0.07573 83  LEU A CD2 
637  N N   . VAL A 84  ? 0.40700 0.38692 0.40676 0.01999  -0.02365 -0.05078 84  VAL A N   
638  C CA  . VAL A 84  ? 0.38601 0.37322 0.38044 0.02177  -0.01997 -0.04507 84  VAL A CA  
639  C C   . VAL A 84  ? 0.48690 0.47884 0.47303 0.02928  -0.01999 -0.04754 84  VAL A C   
640  O O   . VAL A 84  ? 0.43394 0.42730 0.41645 0.03214  -0.02324 -0.05289 84  VAL A O   
641  C CB  . VAL A 84  ? 0.40650 0.39792 0.40306 0.01730  -0.01910 -0.04154 84  VAL A CB  
642  C CG1 . VAL A 84  ? 0.36617 0.36473 0.35829 0.01955  -0.01612 -0.03683 84  VAL A CG1 
643  C CG2 . VAL A 84  ? 0.38123 0.36815 0.38339 0.01208  -0.01761 -0.03733 84  VAL A CG2 
644  N N   . GLY A 85  ? 0.42136 0.41606 0.40459 0.03336  -0.01625 -0.04339 85  GLY A N   
645  C CA  . GLY A 85  ? 0.47296 0.47150 0.44796 0.04219  -0.01479 -0.04457 85  GLY A CA  
646  C C   . GLY A 85  ? 0.50400 0.51110 0.47834 0.04476  -0.00923 -0.03712 85  GLY A C   
647  O O   . GLY A 85  ? 0.41999 0.43010 0.40020 0.03911  -0.00773 -0.03210 85  GLY A O   
648  N N   . GLN A 86  ? 0.42584 0.46366 0.46650 0.03050  0.05800  -0.02933 86  GLN A N   
649  C CA  . GLN A 86  ? 0.46632 0.51251 0.49894 0.02930  0.06158  -0.02410 86  GLN A CA  
650  C C   . GLN A 86  ? 0.45268 0.50967 0.50262 0.02789  0.06273  -0.01285 86  GLN A C   
651  O O   . GLN A 86  ? 0.45400 0.51694 0.49900 0.02381  0.06260  -0.00657 86  GLN A O   
652  C CB  . GLN A 86  ? 0.50699 0.55352 0.52869 0.03389  0.07120  -0.03148 86  GLN A CB  
653  C CG  . GLN A 86  ? 0.54059 0.57901 0.54079 0.03351  0.06871  -0.04215 86  GLN A CG  
654  C CD  . GLN A 86  ? 0.67319 0.71325 0.65601 0.02922  0.06259  -0.03788 86  GLN A CD  
655  O OE1 . GLN A 86  ? 0.66693 0.71161 0.65292 0.02628  0.06089  -0.02790 86  GLN A OE1 
656  N NE2 . GLN A 86  ? 0.76409 0.80011 0.72914 0.02866  0.05894  -0.04540 86  GLN A NE2 
657  N N   . ARG A 87  ? 0.38952 0.44942 0.46026 0.03078  0.06355  -0.00962 87  ARG A N   
658  C CA  . ARG A 87  ? 0.45164 0.52422 0.53949 0.02817  0.06197  0.00219  87  ARG A CA  
659  C C   . ARG A 87  ? 0.44566 0.51830 0.52790 0.01979  0.05202  0.00790  87  ARG A C   
660  O O   . ARG A 87  ? 0.41929 0.49960 0.50082 0.01421  0.05070  0.01436  87  ARG A O   
661  C CB  . ARG A 87  ? 0.46985 0.54579 0.58174 0.03356  0.06347  0.00596  87  ARG A CB  
662  C CG  . ARG A 87  ? 0.44398 0.53684 0.57589 0.03138  0.06154  0.01911  87  ARG A CG  
663  C CD  . ARG A 87  ? 0.50587 0.60216 0.66300 0.03837  0.06306  0.02416  87  ARG A CD  
664  N NE  . ARG A 87  ? 0.58262 0.69732 0.75967 0.03561  0.05861  0.03827  87  ARG A NE  
665  C CZ  . ARG A 87  ? 0.63049 0.75357 0.83335 0.04179  0.05945  0.04670  87  ARG A CZ  
666  N NH1 . ARG A 87  ? 0.54316 0.65521 0.75576 0.05140  0.06546  0.04207  87  ARG A NH1 
667  N NH2 . ARG A 87  ? 0.68767 0.83058 0.90756 0.03803  0.05392  0.06033  87  ARG A NH2 
668  N N   . PHE A 88  ? 0.38625 0.44999 0.46449 0.01835  0.04558  0.00514  88  PHE A N   
669  C CA  . PHE A 88  ? 0.39808 0.46112 0.46920 0.01095  0.03776  0.00917  88  PHE A CA  
670  C C   . PHE A 88  ? 0.42462 0.48345 0.47682 0.00788  0.03802  0.00630  88  PHE A C   
671  O O   . PHE A 88  ? 0.37513 0.43554 0.42305 0.00169  0.03486  0.01080  88  PHE A O   
672  C CB  . PHE A 88  ? 0.40506 0.46051 0.47647 0.01036  0.03221  0.00711  88  PHE A CB  
673  C CG  . PHE A 88  ? 0.39863 0.45394 0.46296 0.00328  0.02565  0.01086  88  PHE A CG  
674  C CD1 . PHE A 88  ? 0.40122 0.46462 0.47406 -0.00145 0.02152  0.01948  88  PHE A CD1 
675  C CD2 . PHE A 88  ? 0.37890 0.42687 0.42790 0.00143  0.02391  0.00587  88  PHE A CD2 
676  C CE1 . PHE A 88  ? 0.40900 0.47153 0.47266 -0.00842 0.01651  0.02143  88  PHE A CE1 
677  C CE2 . PHE A 88  ? 0.41795 0.46493 0.46051 -0.00433 0.01965  0.00836  88  PHE A CE2 
678  C CZ  . PHE A 88  ? 0.36158 0.41504 0.41021 -0.00949 0.01638  0.01533  88  PHE A CZ  
679  N N   . ALA A 89  ? 0.42730 0.48049 0.46783 0.01196  0.04178  -0.00094 89  ALA A N   
680  C CA  . ALA A 89  ? 0.45053 0.50058 0.47416 0.01007  0.04222  -0.00154 89  ALA A CA  
681  C C   . ALA A 89  ? 0.44025 0.49706 0.46553 0.00685  0.04621  0.00525  89  ALA A C   
682  O O   . ALA A 89  ? 0.44201 0.49591 0.45962 0.00194  0.04424  0.00874  89  ALA A O   
683  C CB  . ALA A 89  ? 0.40875 0.45458 0.41953 0.01489  0.04535  -0.00931 89  ALA A CB  
684  N N   . ARG A 90  ? 0.41563 0.48125 0.45226 0.00944  0.05239  0.00725  90  ARG A N   
685  C CA  . ARG A 90  ? 0.43917 0.51355 0.48028 0.00559  0.05653  0.01436  90  ARG A CA  
686  C C   . ARG A 90  ? 0.44867 0.52808 0.49980 -0.00230 0.05040  0.02136  90  ARG A C   
687  O O   . ARG A 90  ? 0.49119 0.57095 0.53824 -0.00907 0.05014  0.02563  90  ARG A O   
688  C CB  . ARG A 90  ? 0.50212 0.58694 0.55559 0.01097  0.06547  0.01494  90  ARG A CB  
689  C CG  . ARG A 90  ? 0.61906 0.70114 0.65780 0.01596  0.07384  0.00947  90  ARG A CG  
690  C CD  . ARG A 90  ? 0.77480 0.86678 0.82577 0.02213  0.08450  0.00869  90  ARG A CD  
691  N NE  . ARG A 90  ? 0.92122 1.01526 0.99153 0.02690  0.08381  0.00723  90  ARG A NE  
692  C CZ  . ARG A 90  ? 0.86592 0.95676 0.93934 0.03504  0.09070  -0.00065 90  ARG A CZ  
693  N NH1 . ARG A 90  ? 0.81629 0.90238 0.87241 0.03876  0.09836  -0.00917 90  ARG A NH1 
694  N NH2 . ARG A 90  ? 0.76109 0.85284 0.85479 0.03939  0.09001  0.00005  90  ARG A NH2 
695  N N   . GLN A 91  ? 0.41292 0.49579 0.47638 -0.00216 0.04534  0.02272  91  GLN A N   
696  C CA  . GLN A 91  ? 0.45781 0.54670 0.52828 -0.01042 0.03851  0.02914  91  GLN A CA  
697  C C   . GLN A 91  ? 0.44863 0.52622 0.50238 -0.01698 0.03383  0.02687  91  GLN A C   
698  O O   . GLN A 91  ? 0.38299 0.46275 0.43582 -0.02568 0.03107  0.03049  91  GLN A O   
699  C CB  . GLN A 91  ? 0.44352 0.53737 0.52774 -0.00840 0.03362  0.03183  91  GLN A CB  
700  C CG  . GLN A 91  ? 0.56038 0.66733 0.66646 -0.00259 0.03767  0.03677  91  GLN A CG  
701  C CD  . GLN A 91  ? 0.73687 0.84530 0.85621 0.00120  0.03345  0.03988  91  GLN A CD  
702  O OE1 . GLN A 91  ? 0.62057 0.71998 0.73152 -0.00063 0.02803  0.03770  91  GLN A OE1 
703  N NE2 . GLN A 91  ? 0.78542 0.90557 0.92684 0.00685  0.03658  0.04587  91  GLN A NE2 
704  N N   . SER A 92  ? 0.39020 0.45584 0.43152 -0.01310 0.03302  0.02061  92  SER A N   
705  C CA  . SER A 92  ? 0.37908 0.43412 0.40687 -0.01740 0.02953  0.01832  92  SER A CA  
706  C C   . SER A 92  ? 0.39570 0.44224 0.41052 -0.01733 0.03342  0.01721  92  SER A C   
707  O O   . SER A 92  ? 0.41257 0.44952 0.41779 -0.02066 0.03179  0.01608  92  SER A O   
708  C CB  . SER A 92  ? 0.40017 0.44890 0.42419 -0.01332 0.02644  0.01349  92  SER A CB  
709  O OG  . SER A 92  ? 0.38891 0.43467 0.40949 -0.00598 0.02949  0.00879  92  SER A OG  
710  N N   . GLY A 93  ? 0.41058 0.46000 0.42470 -0.01323 0.03909  0.01787  93  GLY A N   
711  C CA  . GLY A 93  ? 0.39582 0.43732 0.39659 -0.01194 0.04255  0.01810  93  GLY A CA  
712  C C   . GLY A 93  ? 0.44480 0.47841 0.43431 -0.00600 0.04059  0.01332  93  GLY A C   
713  O O   . GLY A 93  ? 0.44485 0.47181 0.42327 -0.00456 0.04214  0.01487  93  GLY A O   
714  N N   . MET A 94  ? 0.40775 0.44254 0.40089 -0.00273 0.03697  0.00848  94  MET A N   
715  C CA  . MET A 94  ? 0.39852 0.42825 0.38325 0.00182  0.03420  0.00402  94  MET A CA  
716  C C   . MET A 94  ? 0.49635 0.52881 0.47440 0.00721  0.03697  0.00074  94  MET A C   
717  O O   . MET A 94  ? 0.47948 0.51751 0.46229 0.00870  0.04125  -0.00046 94  MET A O   
718  C CB  . MET A 94  ? 0.41299 0.44299 0.40480 0.00192  0.02941  0.00026  94  MET A CB  
719  C CG  . MET A 94  ? 0.49589 0.52105 0.48682 -0.00171 0.02627  0.00142  94  MET A CG  
720  S SD  . MET A 94  ? 0.50873 0.53463 0.50582 -0.00127 0.02157  -0.00217 94  MET A SD  
721  C CE  . MET A 94  ? 0.42513 0.45708 0.43438 -0.00008 0.02164  -0.00312 94  MET A CE  
722  N N   . ILE A 95  ? 0.44287 0.47214 0.40991 0.01026  0.03453  -0.00089 95  ILE A N   
723  C CA  . ILE A 95  ? 0.43657 0.46873 0.39400 0.01444  0.03531  -0.00535 95  ILE A CA  
724  C C   . ILE A 95  ? 0.46964 0.50189 0.42994 0.01570  0.02977  -0.01276 95  ILE A C   
725  O O   . ILE A 95  ? 0.44247 0.47282 0.40495 0.01507  0.02457  -0.01223 95  ILE A O   
726  C CB  . ILE A 95  ? 0.43910 0.46987 0.38187 0.01635  0.03530  -0.00056 95  ILE A CB  
727  C CG1 . ILE A 95  ? 0.54045 0.57056 0.48099 0.01432  0.04191  0.00703  95  ILE A CG1 
728  C CG2 . ILE A 95  ? 0.47281 0.50792 0.40298 0.01972  0.03416  -0.00569 95  ILE A CG2 
729  C CD1 . ILE A 95  ? 0.52603 0.55202 0.45475 0.01560  0.04209  0.01474  95  ILE A CD1 
730  N N   . LEU A 96  ? 0.42658 0.46062 0.38769 0.01729  0.03159  -0.01989 96  LEU A N   
731  C CA  . LEU A 96  ? 0.42211 0.45495 0.38619 0.01737  0.02677  -0.02777 96  LEU A CA  
732  C C   . LEU A 96  ? 0.46863 0.50369 0.41776 0.01851  0.02265  -0.03172 96  LEU A C   
733  O O   . LEU A 96  ? 0.44729 0.48450 0.38300 0.02021  0.02605  -0.03355 96  LEU A O   
734  C CB  . LEU A 96  ? 0.46535 0.49664 0.43751 0.01849  0.03112  -0.03435 96  LEU A CB  
735  C CG  . LEU A 96  ? 0.49405 0.52609 0.48231 0.01816  0.03509  -0.02924 96  LEU A CG  
736  C CD1 . LEU A 96  ? 0.47870 0.50842 0.47647 0.02099  0.03965  -0.03561 96  LEU A CD1 
737  C CD2 . LEU A 96  ? 0.43121 0.46241 0.42942 0.01468  0.02964  -0.02404 96  LEU A CD2 
738  N N   . LEU A 97  ? 0.41444 0.45059 0.36603 0.01731  0.01532  -0.03261 97  LEU A N   
739  C CA  . LEU A 97  ? 0.44778 0.48896 0.38774 0.01775  0.00928  -0.03520 97  LEU A CA  
740  C C   . LEU A 97  ? 0.50387 0.54513 0.44657 0.01498  0.00497  -0.04609 97  LEU A C   
741  O O   . LEU A 97  ? 0.48117 0.51725 0.43667 0.01321  0.00660  -0.05026 97  LEU A O   
742  C CB  . LEU A 97  ? 0.40778 0.45220 0.35039 0.01871  0.00407  -0.02725 97  LEU A CB  
743  C CG  . LEU A 97  ? 0.43950 0.48115 0.37843 0.02109  0.00822  -0.01697 97  LEU A CG  
744  C CD1 . LEU A 97  ? 0.43142 0.47463 0.37427 0.02322  0.00397  -0.01021 97  LEU A CD1 
745  C CD2 . LEU A 97  ? 0.45431 0.49794 0.37659 0.02296  0.01126  -0.01473 97  LEU A CD2 
746  N N   . ALA A 98  ? 0.50400 0.55124 0.43456 0.01408  -0.00102 -0.05021 98  ALA A N   
747  C CA  . ALA A 98  ? 0.47450 0.52189 0.40609 0.00982  -0.00614 -0.06153 98  ALA A CA  
748  C C   . ALA A 98  ? 0.49100 0.54140 0.43943 0.00690  -0.01277 -0.05954 98  ALA A C   
749  O O   . ALA A 98  ? 0.45386 0.50730 0.41032 0.00895  -0.01348 -0.04989 98  ALA A O   
750  C CB  . ALA A 98  ? 0.51547 0.57031 0.42697 0.00852  -0.01146 -0.06653 98  ALA A CB  
751  N N   . GLU A 99  ? 0.49663 0.54571 0.45060 0.00170  -0.01698 -0.06919 99  GLU A N   
752  C CA  . GLU A 99  ? 0.51389 0.56640 0.48567 -0.00177 -0.02210 -0.06689 99  GLU A CA  
753  C C   . GLU A 99  ? 0.46531 0.53224 0.43722 -0.00137 -0.03025 -0.06043 99  GLU A C   
754  O O   . GLU A 99  ? 0.43571 0.50738 0.42316 -0.00208 -0.03230 -0.05502 99  GLU A O   
755  C CB  . GLU A 99  ? 0.56438 0.61134 0.54366 -0.00845 -0.02456 -0.07818 99  GLU A CB  
756  C CG  . GLU A 99  ? 0.58560 0.63681 0.55202 -0.01341 -0.03136 -0.08911 99  GLU A CG  
757  C CD  . GLU A 99  ? 0.63513 0.67949 0.61232 -0.02149 -0.03417 -0.09994 99  GLU A CD  
758  O OE1 . GLU A 99  ? 0.57298 0.60198 0.55505 -0.02157 -0.02697 -0.10589 99  GLU A OE1 
759  O OE2 . GLU A 99  ? 0.60304 0.65759 0.58540 -0.02782 -0.04353 -0.10185 99  GLU A OE2 
760  N N   . GLU A 100 ? 0.46880 0.54357 0.42424 0.00017  -0.03449 -0.06004 100 GLU A N   
761  C CA  . GLU A 100 ? 0.47913 0.56843 0.43481 0.00263  -0.04180 -0.05111 100 GLU A CA  
762  C C   . GLU A 100 ? 0.50100 0.59065 0.44024 0.00890  -0.03874 -0.04317 100 GLU A C   
763  O O   . GLU A 100 ? 0.49208 0.57852 0.41328 0.00852  -0.03641 -0.04817 100 GLU A O   
764  C CB  . GLU A 100 ? 0.52224 0.62462 0.47497 -0.00329 -0.05326 -0.05733 100 GLU A CB  
765  C CG  . GLU A 100 ? 0.49940 0.60274 0.47021 -0.01076 -0.05710 -0.06423 100 GLU A CG  
766  C CD  . GLU A 100 ? 0.55362 0.67056 0.52156 -0.01841 -0.06924 -0.07125 100 GLU A CD  
767  O OE1 . GLU A 100 ? 0.54627 0.67314 0.49663 -0.01771 -0.07543 -0.07058 100 GLU A OE1 
768  O OE2 . GLU A 100 ? 0.51377 0.63196 0.49700 -0.02588 -0.07289 -0.07706 100 GLU A OE2 
769  N N   . GLU A 101 ? 0.43087 0.52351 0.37633 0.01460  -0.03782 -0.03091 101 GLU A N   
770  C CA  . GLU A 101 ? 0.48171 0.57411 0.41344 0.02031  -0.03528 -0.02156 101 GLU A CA  
771  C C   . GLU A 101 ? 0.50435 0.60805 0.44260 0.02530  -0.04127 -0.00990 101 GLU A C   
772  O O   . GLU A 101 ? 0.47269 0.57924 0.42936 0.02652  -0.04202 -0.00692 101 GLU A O   
773  C CB  . GLU A 101 ? 0.46290 0.54131 0.39561 0.02317  -0.02433 -0.01738 101 GLU A CB  
774  C CG  . GLU A 101 ? 0.51280 0.58153 0.44130 0.01995  -0.01749 -0.02627 101 GLU A CG  
775  C CD  . GLU A 101 ? 0.52700 0.59587 0.43498 0.02029  -0.01485 -0.02871 101 GLU A CD  
776  O OE1 . GLU A 101 ? 0.57958 0.65615 0.47418 0.02245  -0.01894 -0.02288 101 GLU A OE1 
777  O OE2 . GLU A 101 ? 0.49952 0.56136 0.40510 0.01870  -0.00823 -0.03597 101 GLU A OE2 
778  N N   . ARG A 102 ? 0.51925 0.62964 0.44273 0.02868  -0.04482 -0.00256 102 ARG A N   
779  C CA  . ARG A 102 ? 0.56551 0.68591 0.49491 0.03526  -0.04979 0.01112  102 ARG A CA  
780  C C   . ARG A 102 ? 0.53017 0.63834 0.45466 0.04167  -0.04110 0.02214  102 ARG A C   
781  O O   . ARG A 102 ? 0.59918 0.70197 0.50555 0.04126  -0.03724 0.02321  102 ARG A O   
782  C CB  . ARG A 102 ? 0.58893 0.72735 0.50580 0.03422  -0.06159 0.01356  102 ARG A CB  
783  C CG  . ARG A 102 ? 0.62503 0.77884 0.55377 0.04083  -0.06940 0.02773  102 ARG A CG  
784  C CD  . ARG A 102 ? 0.71034 0.88341 0.62355 0.03905  -0.08206 0.03116  102 ARG A CD  
785  N NE  . ARG A 102 ? 0.79186 0.96824 0.69205 0.02860  -0.08684 0.01471  102 ARG A NE  
786  C CZ  . ARG A 102 ? 0.88709 1.06051 0.76038 0.02472  -0.08606 0.00863  102 ARG A CZ  
787  N NH1 . ARG A 102 ? 0.93259 1.10187 0.78860 0.02988  -0.08140 0.01886  102 ARG A NH1 
788  N NH2 . ARG A 102 ? 0.83640 1.01016 0.70000 0.01530  -0.08911 -0.00830 102 ARG A NH2 
789  N N   . LEU A 103 ? 0.53051 0.63377 0.47109 0.04714  -0.03729 0.02981  103 LEU A N   
790  C CA  . LEU A 103 ? 0.54301 0.63203 0.48135 0.05238  -0.02868 0.03944  103 LEU A CA  
791  C C   . LEU A 103 ? 0.53311 0.62822 0.47713 0.06112  -0.03219 0.05433  103 LEU A C   
792  O O   . LEU A 103 ? 0.55114 0.66061 0.50871 0.06410  -0.03935 0.05705  103 LEU A O   
793  C CB  . LEU A 103 ? 0.51939 0.59347 0.47036 0.05154  -0.01948 0.03554  103 LEU A CB  
794  C CG  . LEU A 103 ? 0.51516 0.58431 0.46812 0.04409  -0.01633 0.02267  103 LEU A CG  
795  C CD1 . LEU A 103 ? 0.48855 0.54627 0.45399 0.04406  -0.00900 0.02168  103 LEU A CD1 
796  C CD2 . LEU A 103 ? 0.47625 0.53922 0.41329 0.04018  -0.01241 0.01887  103 LEU A CD2 
797  N N   . ASP A 104 ? 0.48375 0.56801 0.41914 0.06530  -0.02674 0.06476  104 ASP A N   
798  C CA  . ASP A 104 ? 0.63013 0.71309 0.57411 0.07484  -0.02654 0.08005  104 ASP A CA  
799  C C   . ASP A 104 ? 0.57285 0.63514 0.52878 0.07698  -0.01516 0.07946  104 ASP A C   
800  O O   . ASP A 104 ? 0.58882 0.63417 0.53627 0.07372  -0.00686 0.07850  104 ASP A O   
801  C CB  . ASP A 104 ? 0.69844 0.78102 0.62532 0.07788  -0.02751 0.09325  104 ASP A CB  
802  C CG  . ASP A 104 ? 0.73924 0.81409 0.67618 0.08815  -0.02454 0.11004  104 ASP A CG  
803  O OD1 . ASP A 104 ? 0.71451 0.80224 0.66632 0.09532  -0.03101 0.11724  104 ASP A OD1 
804  O OD2 . ASP A 104 ? 0.80806 0.86387 0.73961 0.08903  -0.01545 0.11622  104 ASP A OD2 
805  N N   . LEU A 105 ? 0.55014 0.61460 0.52556 0.08178  -0.01455 0.07945  105 LEU A N   
806  C CA  . LEU A 105 ? 0.54668 0.59193 0.53251 0.08389  -0.00360 0.07762  105 LEU A CA  
807  C C   . LEU A 105 ? 0.57266 0.61404 0.56994 0.09562  -0.00144 0.09171  105 LEU A C   
808  O O   . LEU A 105 ? 0.51552 0.56927 0.53005 0.10236  -0.00444 0.09494  105 LEU A O   
809  C CB  . LEU A 105 ? 0.49638 0.54552 0.49484 0.08022  -0.00221 0.06567  105 LEU A CB  
810  C CG  . LEU A 105 ? 0.52187 0.57455 0.51198 0.06953  -0.00445 0.05282  105 LEU A CG  
811  C CD1 . LEU A 105 ? 0.48467 0.54267 0.48879 0.06663  -0.00360 0.04387  105 LEU A CD1 
812  C CD2 . LEU A 105 ? 0.45702 0.49182 0.43384 0.06367  0.00284  0.04921  105 LEU A CD2 
813  N N   . TYR A 106 ? 0.53278 0.55703 0.52184 0.09816  0.00421  0.10077  106 TYR A N   
814  C CA  . TYR A 106 ? 0.54593 0.56104 0.54577 0.10968  0.00812  0.11504  106 TYR A CA  
815  C C   . TYR A 106 ? 0.59011 0.62915 0.59957 0.11883  -0.00260 0.12759  106 TYR A C   
816  O O   . TYR A 106 ? 0.56979 0.61021 0.59850 0.12963  -0.00080 0.13560  106 TYR A O   
817  C CB  . TYR A 106 ? 0.51520 0.51306 0.53021 0.11303  0.01909  0.10893  106 TYR A CB  
818  C CG  . TYR A 106 ? 0.53893 0.51994 0.54494 0.10194  0.02675  0.09416  106 TYR A CG  
819  C CD1 . TYR A 106 ? 0.55316 0.51249 0.54716 0.09690  0.03348  0.09528  106 TYR A CD1 
820  C CD2 . TYR A 106 ? 0.49213 0.48035 0.50211 0.09589  0.02668  0.08018  106 TYR A CD2 
821  C CE1 . TYR A 106 ? 0.53959 0.48650 0.52637 0.08609  0.03910  0.08258  106 TYR A CE1 
822  C CE2 . TYR A 106 ? 0.51889 0.49389 0.52052 0.08566  0.03246  0.06817  106 TYR A CE2 
823  C CZ  . TYR A 106 ? 0.50931 0.46449 0.49968 0.08083  0.03823  0.06934  106 TYR A CZ  
824  O OH  . TYR A 106 ? 0.53352 0.47833 0.51700 0.07028  0.04277  0.05826  106 TYR A OH  
825  N N   . GLY A 107 ? 0.60185 0.66092 0.59809 0.11437  -0.01390 0.12903  107 GLY A N   
826  C CA  . GLY A 107 ? 0.67742 0.76088 0.67811 0.12108  -0.02607 0.14211  107 GLY A CA  
827  C C   . GLY A 107 ? 0.69154 0.80193 0.70034 0.11726  -0.03700 0.13378  107 GLY A C   
828  O O   . GLY A 107 ? 0.78702 0.92079 0.79183 0.11779  -0.04984 0.14104  107 GLY A O   
829  N N   A ARG A 108 ? 0.63209 0.74017 0.65182 0.11271  -0.03252 0.11918  108 ARG A N   
830  N N   B ARG A 108 ? 0.65751 0.76561 0.67725 0.11270  -0.03253 0.11917  108 ARG A N   
831  C CA  A ARG A 108 ? 0.65565 0.78757 0.68487 0.10789  -0.04190 0.11103  108 ARG A CA  
832  C CA  B ARG A 108 ? 0.63710 0.76902 0.66640 0.10789  -0.04188 0.11100  108 ARG A CA  
833  C C   A ARG A 108 ? 0.63889 0.77046 0.64967 0.09448  -0.04451 0.09546  108 ARG A C   
834  C C   B ARG A 108 ? 0.65917 0.79077 0.67014 0.09448  -0.04449 0.09540  108 ARG A C   
835  O O   A ARG A 108 ? 0.60491 0.71647 0.60572 0.08916  -0.03535 0.08657  108 ARG A O   
836  O O   B ARG A 108 ? 0.63046 0.74217 0.63204 0.08913  -0.03527 0.08625  108 ARG A O   
837  C CB  A ARG A 108 ? 0.63864 0.77088 0.69300 0.11151  -0.03539 0.10619  108 ARG A CB  
838  C CB  B ARG A 108 ? 0.66520 0.79717 0.71939 0.11137  -0.03527 0.10597  108 ARG A CB  
839  C CG  A ARG A 108 ? 0.65169 0.76480 0.70329 0.10421  -0.02442 0.09084  108 ARG A CG  
840  C CG  B ARG A 108 ? 0.65747 0.76231 0.70974 0.10909  -0.02056 0.09637  108 ARG A CG  
841  C CD  A ARG A 108 ? 0.63013 0.74804 0.70539 0.10762  -0.01879 0.08697  108 ARG A CD  
842  C CD  B ARG A 108 ? 0.64374 0.75297 0.71383 0.10746  -0.01585 0.08663  108 ARG A CD  
843  N NE  A ARG A 108 ? 0.62297 0.71813 0.70397 0.11466  -0.00463 0.08834  108 ARG A NE  
844  N NE  B ARG A 108 ? 0.62036 0.72694 0.71159 0.11929  -0.00788 0.09374  108 ARG A NE  
845  C CZ  A ARG A 108 ? 0.59996 0.69741 0.70250 0.12335  0.00226  0.09088  108 ARG A CZ  
846  C CZ  B ARG A 108 ? 0.62059 0.70187 0.71134 0.12438  0.00518  0.09411  108 ARG A CZ  
847  N NH1 A ARG A 108 ? 0.58883 0.71227 0.71181 0.12628  -0.00368 0.09354  108 ARG A NH1 
848  N NH1 B ARG A 108 ? 0.56876 0.62641 0.63991 0.11804  0.01101  0.08867  108 ARG A NH1 
849  N NH2 A ARG A 108 ? 0.56329 0.63645 0.66729 0.12890  0.01590  0.09034  108 ARG A NH2 
850  N NH2 B ARG A 108 ? 0.55264 0.63241 0.66384 0.13592  0.01288  0.09977  108 ARG A NH2 
851  N N   . GLU A 109 ? 0.58656 0.74051 0.59323 0.08906  -0.05720 0.09247  109 GLU A N   
852  C CA  . GLU A 109 ? 0.63688 0.79101 0.62639 0.07707  -0.06015 0.07771  109 GLU A CA  
853  C C   . GLU A 109 ? 0.58891 0.74494 0.59353 0.07090  -0.05856 0.06434  109 GLU A C   
854  O O   . GLU A 109 ? 0.58731 0.76133 0.61118 0.07200  -0.06469 0.06578  109 GLU A O   
855  C CB  . GLU A 109 ? 0.64288 0.81833 0.61847 0.07326  -0.07431 0.07972  109 GLU A CB  
856  C CG  . GLU A 109 ? 0.71700 0.88562 0.66482 0.07261  -0.07371 0.08443  109 GLU A CG  
857  N N   . VAL A 110 ? 0.51759 0.65630 0.51470 0.06444  -0.05035 0.05259  110 VAL A N   
858  C CA  . VAL A 110 ? 0.48083 0.61774 0.49129 0.05894  -0.04694 0.04162  110 VAL A CA  
859  C C   . VAL A 110 ? 0.51971 0.65340 0.51711 0.04844  -0.04879 0.02813  110 VAL A C   
860  O O   . VAL A 110 ? 0.47693 0.59725 0.45708 0.04638  -0.04399 0.02506  110 VAL A O   
861  C CB  . VAL A 110 ? 0.47904 0.59657 0.49635 0.06210  -0.03382 0.04137  110 VAL A CB  
862  C CG1 . VAL A 110 ? 0.42425 0.54236 0.45453 0.05641  -0.03083 0.03176  110 VAL A CG1 
863  C CG2 . VAL A 110 ? 0.55185 0.66864 0.58114 0.07328  -0.03016 0.05379  110 VAL A CG2 
864  N N   . LEU A 111 ? 0.42567 0.57120 0.43289 0.04193  -0.05497 0.02030  111 LEU A N   
865  C CA  . LEU A 111 ? 0.45734 0.59685 0.45693 0.03233  -0.05505 0.00675  111 LEU A CA  
866  C C   . LEU A 111 ? 0.42018 0.54534 0.42927 0.03049  -0.04507 0.00208  111 LEU A C   
867  O O   . LEU A 111 ? 0.40585 0.53455 0.43257 0.03265  -0.04237 0.00527  111 LEU A O   
868  C CB  . LEU A 111 ? 0.42136 0.57846 0.42791 0.02508  -0.06627 0.00051  111 LEU A CB  
869  C CG  . LEU A 111 ? 0.45386 0.60403 0.45929 0.01493  -0.06600 -0.01382 111 LEU A CG  
870  C CD1 . LEU A 111 ? 0.45509 0.59296 0.43676 0.01218  -0.06368 -0.02167 111 LEU A CD1 
871  C CD2 . LEU A 111 ? 0.43617 0.60429 0.45271 0.00735  -0.07722 -0.01860 111 LEU A CD2 
872  N N   . ILE A 112 ? 0.37631 0.48651 0.37382 0.02677  -0.03934 -0.00480 112 ILE A N   
873  C CA  . ILE A 112 ? 0.40826 0.50645 0.41322 0.02397  -0.03140 -0.00890 112 ILE A CA  
874  C C   . ILE A 112 ? 0.44703 0.54167 0.44966 0.01621  -0.03282 -0.01978 112 ILE A C   
875  O O   . ILE A 112 ? 0.41589 0.50986 0.40479 0.01411  -0.03565 -0.02509 112 ILE A O   
876  C CB  . ILE A 112 ? 0.39110 0.47384 0.38801 0.02746  -0.02212 -0.00507 112 ILE A CB  
877  C CG1 . ILE A 112 ? 0.41365 0.49034 0.39247 0.02671  -0.02114 -0.00717 112 ILE A CG1 
878  C CG2 . ILE A 112 ? 0.38733 0.46993 0.38822 0.03507  -0.01943 0.00496  112 ILE A CG2 
879  C CD1 . ILE A 112 ? 0.41557 0.47788 0.38891 0.02731  -0.01211 -0.00519 112 ILE A CD1 
880  N N   . MET A 113 ? 0.36624 0.45818 0.38216 0.01213  -0.03027 -0.02290 113 MET A N   
881  C CA  . MET A 113 ? 0.38697 0.47249 0.40402 0.00540  -0.03013 -0.03191 113 MET A CA  
882  C C   . MET A 113 ? 0.41091 0.49172 0.44188 0.00310  -0.02494 -0.03035 113 MET A C   
883  O O   . MET A 113 ? 0.38801 0.47278 0.42714 0.00582  -0.02231 -0.02404 113 MET A O   
884  C CB  . MET A 113 ? 0.42445 0.51932 0.44394 -0.00059 -0.03904 -0.03915 113 MET A CB  
885  C CG  . MET A 113 ? 0.46201 0.57181 0.49942 -0.00325 -0.04470 -0.03641 113 MET A CG  
886  S SD  . MET A 113 ? 0.49394 0.62244 0.52909 -0.00746 -0.05832 -0.04003 113 MET A SD  
887  C CE  . MET A 113 ? 0.47345 0.59258 0.51045 -0.01887 -0.06011 -0.05427 113 MET A CE  
888  N N   . HIS A 114 ? 0.37996 0.45202 0.41328 -0.00169 -0.02295 -0.03590 114 HIS A N   
889  C CA  . HIS A 114 ? 0.37448 0.44280 0.41997 -0.00439 -0.01857 -0.03307 114 HIS A CA  
890  C C   . HIS A 114 ? 0.38336 0.46267 0.44453 -0.00833 -0.02203 -0.03196 114 HIS A C   
891  O O   . HIS A 114 ? 0.36146 0.44388 0.43121 -0.00790 -0.01804 -0.02626 114 HIS A O   
892  C CB  . HIS A 114 ? 0.36949 0.42625 0.41593 -0.00783 -0.01594 -0.03745 114 HIS A CB  
893  C CG  . HIS A 114 ? 0.39672 0.45071 0.45522 -0.01106 -0.01243 -0.03305 114 HIS A CG  
894  N ND1 . HIS A 114 ? 0.38520 0.43893 0.44307 -0.00903 -0.00760 -0.02590 114 HIS A ND1 
895  C CD2 . HIS A 114 ? 0.40234 0.45386 0.47311 -0.01675 -0.01310 -0.03435 114 HIS A CD2 
896  C CE1 . HIS A 114 ? 0.39755 0.45004 0.46537 -0.01315 -0.00561 -0.02258 114 HIS A CE1 
897  N NE2 . HIS A 114 ? 0.40091 0.45183 0.47759 -0.01763 -0.00873 -0.02684 114 HIS A NE2 
898  N N   . GLY A 115 ? 0.37996 0.46580 0.44492 -0.01289 -0.02915 -0.03770 115 GLY A N   
899  C CA  . GLY A 115 ? 0.34681 0.44594 0.42833 -0.01754 -0.03344 -0.03653 115 GLY A CA  
900  C C   . GLY A 115 ? 0.39051 0.48551 0.48259 -0.02679 -0.03554 -0.04238 115 GLY A C   
901  O O   . GLY A 115 ? 0.42689 0.53399 0.53236 -0.03256 -0.04096 -0.04318 115 GLY A O   
902  N N   . ASP A 116 ? 0.39991 0.47837 0.48813 -0.02846 -0.03135 -0.04595 116 ASP A N   
903  C CA  . ASP A 116 ? 0.42690 0.49861 0.52689 -0.03695 -0.03239 -0.05063 116 ASP A CA  
904  C C   . ASP A 116 ? 0.41857 0.49282 0.51692 -0.04331 -0.04062 -0.06143 116 ASP A C   
905  O O   . ASP A 116 ? 0.45572 0.53188 0.56795 -0.05217 -0.04414 -0.06451 116 ASP A O   
906  C CB  . ASP A 116 ? 0.44738 0.50053 0.54500 -0.03598 -0.02598 -0.05117 116 ASP A CB  
907  C CG  . ASP A 116 ? 0.47322 0.51659 0.55441 -0.03138 -0.02493 -0.05819 116 ASP A CG  
908  O OD1 . ASP A 116 ? 0.48150 0.53038 0.54965 -0.02542 -0.02509 -0.05674 116 ASP A OD1 
909  O OD2 . ASP A 116 ? 0.45723 0.48680 0.53920 -0.03354 -0.02308 -0.06491 116 ASP A OD2 
910  N N   . THR A 117 ? 0.42915 0.50414 0.51019 -0.03985 -0.04393 -0.06716 117 THR A N   
911  C CA  . THR A 117 ? 0.44007 0.51840 0.51565 -0.04659 -0.05237 -0.07832 117 THR A CA  
912  C C   . THR A 117 ? 0.45723 0.55762 0.54377 -0.05139 -0.06172 -0.07570 117 THR A C   
913  O O   . THR A 117 ? 0.45825 0.56386 0.54283 -0.05940 -0.07034 -0.08481 117 THR A O   
914  C CB  . THR A 117 ? 0.52389 0.59925 0.57578 -0.04140 -0.05299 -0.08382 117 THR A CB  
915  O OG1 . THR A 117 ? 0.46555 0.55428 0.51142 -0.03362 -0.05409 -0.07408 117 THR A OG1 
916  C CG2 . THR A 117 ? 0.47124 0.52685 0.51480 -0.03666 -0.04333 -0.08652 117 THR A CG2 
917  N N   . LEU A 118 ? 0.40706 0.52106 0.50533 -0.04689 -0.06014 -0.06388 118 LEU A N   
918  C CA  . LEU A 118 ? 0.40969 0.54676 0.52342 -0.05048 -0.06779 -0.05965 118 LEU A CA  
919  C C   . LEU A 118 ? 0.48003 0.62016 0.61683 -0.06011 -0.06752 -0.05904 118 LEU A C   
920  O O   . LEU A 118 ? 0.45356 0.61394 0.60611 -0.06541 -0.07451 -0.05684 118 LEU A O   
921  C CB  . LEU A 118 ? 0.39470 0.54476 0.51168 -0.03996 -0.06462 -0.04727 118 LEU A CB  
922  C CG  . LEU A 118 ? 0.41098 0.55878 0.50734 -0.03024 -0.06447 -0.04525 118 LEU A CG  
923  C CD1 . LEU A 118 ? 0.44393 0.59854 0.54531 -0.01991 -0.05873 -0.03337 118 LEU A CD1 
924  C CD2 . LEU A 118 ? 0.43580 0.59667 0.52325 -0.03291 -0.07629 -0.04955 118 LEU A CD2 
925  N N   . CYS A 119 ? 0.43522 0.55709 0.57565 -0.06249 -0.05969 -0.05964 119 CYS A N   
926  C CA  . CYS A 119 ? 0.49471 0.61823 0.65705 -0.07120 -0.05780 -0.05656 119 CYS A CA  
927  C C   . CYS A 119 ? 0.53453 0.64792 0.70085 -0.08366 -0.06332 -0.06827 119 CYS A C   
928  O O   . CYS A 119 ? 0.58656 0.68162 0.75838 -0.08829 -0.05817 -0.07005 119 CYS A O   
929  C CB  . CYS A 119 ? 0.51198 0.62250 0.67638 -0.06699 -0.04650 -0.04854 119 CYS A CB  
930  S SG  . CYS A 119 ? 0.50311 0.62144 0.65986 -0.05366 -0.03923 -0.03738 119 CYS A SG  
931  N N   . THR A 120 ? 0.53198 0.65773 0.69552 -0.08938 -0.07428 -0.07614 120 THR A N   
932  C CA  . THR A 120 ? 0.57614 0.69161 0.73857 -0.10179 -0.08061 -0.09037 120 THR A CA  
933  C C   . THR A 120 ? 0.64055 0.75756 0.82827 -0.11505 -0.08173 -0.08973 120 THR A C   
934  O O   . THR A 120 ? 0.63937 0.74497 0.82821 -0.12682 -0.08631 -0.10207 120 THR A O   
935  C CB  . THR A 120 ? 0.57124 0.70248 0.72156 -0.10508 -0.09318 -0.09849 120 THR A CB  
936  O OG1 . THR A 120 ? 0.52126 0.68301 0.68786 -0.10585 -0.10022 -0.08889 120 THR A OG1 
937  C CG2 . THR A 120 ? 0.53724 0.66334 0.66042 -0.09331 -0.09141 -0.10005 120 THR A CG2 
938  N N   . ASP A 121 ? 0.57640 0.70641 0.78392 -0.11398 -0.07707 -0.07621 121 ASP A N   
939  C CA  . ASP A 121 ? 0.61914 0.74999 0.85134 -0.12644 -0.07620 -0.07354 121 ASP A CA  
940  C C   . ASP A 121 ? 0.63695 0.74053 0.87140 -0.12691 -0.06568 -0.07124 121 ASP A C   
941  O O   . ASP A 121 ? 0.60964 0.70758 0.86259 -0.13840 -0.06471 -0.07039 121 ASP A O   
942  C CB  . ASP A 121 ? 0.59108 0.75007 0.84409 -0.12517 -0.07485 -0.05955 121 ASP A CB  
943  C CG  . ASP A 121 ? 0.63530 0.82388 0.89272 -0.12591 -0.08624 -0.06019 121 ASP A CG  
944  O OD1 . ASP A 121 ? 0.65729 0.85069 0.91688 -0.13767 -0.09756 -0.07051 121 ASP A OD1 
945  O OD2 . ASP A 121 ? 0.60690 0.81333 0.86486 -0.11459 -0.08409 -0.05055 121 ASP A OD2 
946  N N   . ASP A 122 ? 0.58458 0.67203 0.80202 -0.11505 -0.05810 -0.06919 122 ASP A N   
947  C CA  . ASP A 122 ? 0.63627 0.69835 0.85511 -0.11430 -0.04915 -0.06641 122 ASP A CA  
948  C C   . ASP A 122 ? 0.64923 0.68705 0.85495 -0.11575 -0.05054 -0.08152 122 ASP A C   
949  O O   . ASP A 122 ? 0.60120 0.62707 0.78953 -0.10561 -0.04648 -0.08408 122 ASP A O   
950  C CB  . ASP A 122 ? 0.62258 0.68381 0.83284 -0.10131 -0.04033 -0.05442 122 ASP A CB  
951  C CG  . ASP A 122 ? 0.62014 0.66253 0.83742 -0.10164 -0.03186 -0.04644 122 ASP A CG  
952  O OD1 . ASP A 122 ? 0.64146 0.66423 0.86520 -0.10842 -0.03173 -0.05243 122 ASP A OD1 
953  O OD2 . ASP A 122 ? 0.61585 0.66273 0.83199 -0.09524 -0.02537 -0.03400 122 ASP A OD2 
954  N N   . GLN A 123 ? 0.47906 0.64936 1.07251 0.00930  -0.15011 -0.20600 123 GLN A N   
955  C CA  . GLN A 123 ? 0.53190 0.69274 1.11049 0.01165  -0.16491 -0.22080 123 GLN A CA  
956  C C   . GLN A 123 ? 0.49037 0.62354 1.05648 -0.00281 -0.14760 -0.20745 123 GLN A C   
957  O O   . GLN A 123 ? 0.52372 0.64317 1.05834 0.00210  -0.15517 -0.21336 123 GLN A O   
958  C CB  . GLN A 123 ? 0.62248 0.80763 1.25783 0.00934  -0.18618 -0.25017 123 GLN A CB  
959  C CG  . GLN A 123 ? 0.67178 0.88756 1.32259 0.02493  -0.20542 -0.26537 123 GLN A CG  
960  C CD  . GLN A 123 ? 0.83027 1.05202 1.44487 0.04678  -0.23286 -0.28451 123 GLN A CD  
961  O OE1 . GLN A 123 ? 0.81644 1.02323 1.40343 0.04870  -0.23876 -0.29074 123 GLN A OE1 
962  N NE2 . GLN A 123 ? 0.90829 1.15251 1.52096 0.06475  -0.24961 -0.29360 123 GLN A NE2 
963  N N   . GLY A 124 ? 0.51122 0.63687 1.09963 -0.01915 -0.12453 -0.18949 124 GLY A N   
964  C CA  . GLY A 124 ? 0.38329 0.48167 0.95343 -0.03029 -0.10777 -0.17406 124 GLY A CA  
965  C C   . GLY A 124 ? 0.50586 0.58462 1.00907 -0.02060 -0.09994 -0.15743 124 GLY A C   
966  O O   . GLY A 124 ? 0.49723 0.55723 0.97211 -0.02118 -0.09854 -0.15527 124 GLY A O   
967  N N   . TYR A 125 ? 0.49498 0.57792 0.97407 -0.01163 -0.09475 -0.14606 125 TYR A N   
968  C CA  . TYR A 125 ? 0.48473 0.54894 0.90272 -0.00276 -0.08852 -0.13144 125 TYR A CA  
969  C C   . TYR A 125 ? 0.48292 0.54663 0.86545 0.01221  -0.10759 -0.14424 125 TYR A C   
970  O O   . TYR A 125 ? 0.52028 0.56670 0.86104 0.01456  -0.10359 -0.13736 125 TYR A O   
971  C CB  . TYR A 125 ? 0.50882 0.57539 0.91084 0.00380  -0.07947 -0.11733 125 TYR A CB  
972  C CG  . TYR A 125 ? 0.45420 0.50294 0.79550 0.01490  -0.07827 -0.10634 125 TYR A CG  
973  C CD1 . TYR A 125 ? 0.49257 0.51936 0.80340 0.00821  -0.06396 -0.09227 125 TYR A CD1 
974  C CD2 . TYR A 125 ? 0.43887 0.49267 0.75457 0.03199  -0.09167 -0.10996 125 TYR A CD2 
975  C CE1 . TYR A 125 ? 0.47573 0.48717 0.73550 0.01642  -0.06200 -0.08255 125 TYR A CE1 
976  C CE2 . TYR A 125 ? 0.48282 0.51851 0.74457 0.04069  -0.08919 -0.09827 125 TYR A CE2 
977  C CZ  . TYR A 125 ? 0.49485 0.50999 0.73054 0.03194  -0.07388 -0.08489 125 TYR A CZ  
978  O OH  . TYR A 125 ? 0.51572 0.51395 0.70213 0.03873  -0.07040 -0.07344 125 TYR A OH  
979  N N   . LEU A 126 ? 0.46713 0.55143 0.86560 0.02307  -0.12832 -0.16316 126 LEU A N   
980  C CA  . LEU A 126 ? 0.54066 0.62643 0.90139 0.03976  -0.14672 -0.17481 126 LEU A CA  
981  C C   . LEU A 126 ? 0.54883 0.62632 0.90459 0.03591  -0.15146 -0.18603 126 LEU A C   
982  O O   . LEU A 126 ? 0.54790 0.61686 0.85691 0.04600  -0.15519 -0.18554 126 LEU A O   
983  C CB  . LEU A 126 ? 0.53709 0.64886 0.91943 0.05294  -0.16963 -0.19469 126 LEU A CB  
984  C CG  . LEU A 126 ? 0.56079 0.67821 0.92553 0.06596  -0.17023 -0.18442 126 LEU A CG  
985  C CD1 . LEU A 126 ? 0.60746 0.74765 0.97552 0.08478  -0.19695 -0.20465 126 LEU A CD1 
986  C CD2 . LEU A 126 ? 0.64119 0.73414 0.94400 0.07219  -0.15775 -0.16189 126 LEU A CD2 
987  N N   . ALA A 127 ? 0.48348 0.56302 0.88759 0.02150  -0.15072 -0.19588 127 ALA A N   
988  C CA  . ALA A 127 ? 0.47226 0.54030 0.87387 0.01710  -0.15328 -0.20526 127 ALA A CA  
989  C C   . ALA A 127 ? 0.52155 0.56581 0.88289 0.01269  -0.13383 -0.18401 127 ALA A C   
990  O O   . ALA A 127 ? 0.57854 0.61504 0.90545 0.01943  -0.13722 -0.18803 127 ALA A O   
991  C CB  . ALA A 127 ? 0.47682 0.54748 0.94103 0.00103  -0.15408 -0.21657 127 ALA A CB  
992  N N   . PHE A 128 ? 0.47841 0.51282 0.84440 0.00185  -0.11338 -0.16222 128 PHE A N   
993  C CA  . PHE A 128 ? 0.50409 0.51799 0.83288 -0.00176 -0.09574 -0.14255 128 PHE A CA  
994  C C   . PHE A 128 ? 0.47695 0.48768 0.74963 0.01217  -0.09747 -0.13642 128 PHE A C   
995  O O   . PHE A 128 ? 0.53951 0.53935 0.77927 0.01421  -0.09357 -0.13324 128 PHE A O   
996  C CB  . PHE A 128 ? 0.48717 0.49440 0.82931 -0.01328 -0.07544 -0.12183 128 PHE A CB  
997  C CG  . PHE A 128 ? 0.54705 0.53608 0.84908 -0.01500 -0.05872 -0.10200 128 PHE A CG  
998  C CD1 . PHE A 128 ? 0.58702 0.56130 0.88861 -0.02361 -0.04934 -0.09640 128 PHE A CD1 
999  C CD2 . PHE A 128 ? 0.49129 0.47768 0.75777 -0.00769 -0.05324 -0.08968 128 PHE A CD2 
1000 C CE1 . PHE A 128 ? 0.51566 0.47585 0.78279 -0.02479 -0.03536 -0.07999 128 PHE A CE1 
1001 C CE2 . PHE A 128 ? 0.53297 0.50362 0.76638 -0.01011 -0.03882 -0.07339 128 PHE A CE2 
1002 C CZ  . PHE A 128 ? 0.54645 0.50548 0.78063 -0.01865 -0.03012 -0.06909 128 PHE A CZ  
1003 N N   . ARG A 129 ? 0.48851 0.50871 0.75070 0.02203  -0.10289 -0.13421 129 ARG A N   
1004 C CA  . ARG A 129 ? 0.52702 0.54192 0.73640 0.03520  -0.10406 -0.12625 129 ARG A CA  
1005 C C   . ARG A 129 ? 0.50858 0.52784 0.69314 0.04613  -0.11819 -0.14122 129 ARG A C   
1006 O O   . ARG A 129 ? 0.53098 0.54015 0.67314 0.05011  -0.11180 -0.13279 129 ARG A O   
1007 C CB  . ARG A 129 ? 0.50524 0.52944 0.71152 0.04590  -0.11070 -0.12356 129 ARG A CB  
1008 C CG  . ARG A 129 ? 0.53440 0.54882 0.68588 0.05884  -0.11013 -0.11166 129 ARG A CG  
1009 C CD  . ARG A 129 ? 0.49311 0.51623 0.64108 0.07263  -0.12058 -0.11129 129 ARG A CD  
1010 N NE  . ARG A 129 ? 0.55788 0.56513 0.65570 0.08191  -0.11510 -0.09403 129 ARG A NE  
1011 C CZ  . ARG A 129 ? 0.58779 0.59187 0.64339 0.09399  -0.12211 -0.09377 129 ARG A CZ  
1012 N NH1 . ARG A 129 ? 0.57422 0.59149 0.62871 0.10033  -0.13629 -0.11164 129 ARG A NH1 
1013 N NH2 . ARG A 129 ? 0.59578 0.58295 0.60936 0.10011  -0.11450 -0.07523 129 ARG A NH2 
1014 N N   . ALA A 130 ? 0.49376 0.52950 0.70512 0.05129  -0.13735 -0.16437 130 ALA A N   
1015 C CA  . ALA A 130 ? 0.55160 0.59391 0.73951 0.06352  -0.15224 -0.18153 130 ALA A CA  
1016 C C   . ALA A 130 ? 0.57877 0.60850 0.75437 0.05675  -0.14253 -0.18059 130 ALA A C   
1017 O O   . ALA A 130 ? 0.60527 0.63418 0.73971 0.06660  -0.14379 -0.18191 130 ALA A O   
1018 C CB  . ALA A 130 ? 0.50059 0.56274 0.72791 0.06806  -0.17491 -0.20948 130 ALA A CB  
1019 N N   . LYS A 131 ? 0.54322 0.56361 0.75365 0.04067  -0.13228 -0.17765 131 LYS A N   
1020 C CA  . LYS A 131 ? 0.56485 0.57310 0.76712 0.03504  -0.12400 -0.17726 131 LYS A CA  
1021 C C   . LYS A 131 ? 0.53474 0.53107 0.69136 0.03531  -0.10676 -0.15574 131 LYS A C   
1022 O O   . LYS A 131 ? 0.52207 0.51832 0.64577 0.04251  -0.10662 -0.15878 131 LYS A O   
1023 C CB  . LYS A 131 ? 0.56064 0.55940 0.80944 0.01844  -0.11638 -0.17569 131 LYS A CB  
1024 C CG  . LYS A 131 ? 0.69888 0.70157 0.98523 0.01693  -0.13142 -0.20042 131 LYS A CG  
1025 C CD  . LYS A 131 ? 0.66333 0.67967 0.99662 0.01376  -0.14361 -0.21301 131 LYS A CD  
1026 C CE  . LYS A 131 ? 0.68783 0.70708 1.06177 0.01143  -0.15964 -0.23931 131 LYS A CE  
1027 N NZ  . LYS A 131 ? 0.77581 0.81033 1.12988 0.02889  -0.18150 -0.26444 131 LYS A NZ  
1028 N N   . VAL A 132 ? 0.55045 0.53780 0.70587 0.02748  -0.09185 -0.13468 132 VAL A N   
1029 C CA  . VAL A 132 ? 0.53199 0.50695 0.65113 0.02515  -0.07513 -0.11530 132 VAL A CA  
1030 C C   . VAL A 132 ? 0.48970 0.46688 0.56366 0.03727  -0.07648 -0.10887 132 VAL A C   
1031 O O   . VAL A 132 ? 0.51905 0.48693 0.56242 0.03548  -0.06334 -0.09422 132 VAL A O   
1032 C CB  . VAL A 132 ? 0.46622 0.43035 0.59744 0.01349  -0.05909 -0.09619 132 VAL A CB  
1033 C CG1 . VAL A 132 ? 0.47247 0.43153 0.64197 0.00129  -0.05431 -0.09808 132 VAL A CG1 
1034 C CG2 . VAL A 132 ? 0.49576 0.46528 0.63515 0.01664  -0.06185 -0.09136 132 VAL A CG2 
1035 N N   . HIS A 133 ? 0.50657 0.49570 0.57581 0.04969  -0.09208 -0.11912 133 HIS A N   
1036 C CA  . HIS A 133 ? 0.54800 0.53865 0.57150 0.06327  -0.09472 -0.11311 133 HIS A CA  
1037 C C   . HIS A 133 ? 0.62506 0.62719 0.62698 0.07529  -0.10609 -0.12963 133 HIS A C   
1038 O O   . HIS A 133 ? 0.63494 0.63993 0.59607 0.08806  -0.10860 -0.12512 133 HIS A O   
1039 C CB  . HIS A 133 ? 0.52931 0.52528 0.55494 0.07235  -0.10476 -0.11139 133 HIS A CB  
1040 C CG  . HIS A 133 ? 0.57614 0.55853 0.59848 0.06635  -0.09113 -0.09017 133 HIS A CG  
1041 N ND1 . HIS A 133 ? 0.56774 0.54691 0.62669 0.05391  -0.08331 -0.08610 133 HIS A ND1 
1042 C CD2 . HIS A 133 ? 0.55145 0.52214 0.53837 0.07151  -0.08391 -0.07228 133 HIS A CD2 
1043 C CE1 . HIS A 133 ? 0.54120 0.50856 0.58683 0.05252  -0.07258 -0.06841 133 HIS A CE1 
1044 N NE2 . HIS A 133 ? 0.61327 0.57406 0.61669 0.06265  -0.07312 -0.05992 133 HIS A NE2 
1045 N N   . THR A 134 ? 0.55683 0.56500 0.58432 0.07223  -0.11284 -0.14845 134 THR A N   
1046 C CA  . THR A 134 ? 0.62773 0.64694 0.63455 0.08391  -0.12252 -0.16583 134 THR A CA  
1047 C C   . THR A 134 ? 0.58830 0.60084 0.55901 0.08220  -0.10540 -0.15262 134 THR A C   
1048 O O   . THR A 134 ? 0.59722 0.59894 0.58142 0.06893  -0.09140 -0.14387 134 THR A O   
1049 C CB  . THR A 134 ? 0.57292 0.59763 0.62102 0.08033  -0.13425 -0.19023 134 THR A CB  
1050 O OG1 . THR A 134 ? 0.56060 0.59314 0.64663 0.08025  -0.14938 -0.20234 134 THR A OG1 
1051 C CG2 . THR A 134 ? 0.60248 0.63976 0.62877 0.09433  -0.14551 -0.21111 134 THR A CG2 
1052 N N   . PRO A 135 ? 0.64824 0.66781 0.57350 0.09531  -0.10542 -0.15021 135 PRO A N   
1053 C CA  . PRO A 135 ? 0.63474 0.64915 0.52772 0.09191  -0.08645 -0.13481 135 PRO A CA  
1054 C C   . PRO A 135 ? 0.65498 0.67143 0.56212 0.08584  -0.08100 -0.14551 135 PRO A C   
1055 O O   . PRO A 135 ? 0.61294 0.62064 0.51801 0.07492  -0.06386 -0.13125 135 PRO A O   
1056 C CB  . PRO A 135 ? 0.71157 0.73688 0.55628 0.10932  -0.09045 -0.13428 135 PRO A CB  
1057 C CG  . PRO A 135 ? 0.70998 0.73863 0.55679 0.11956  -0.10727 -0.13807 135 PRO A CG  
1058 C CD  . PRO A 135 ? 0.66827 0.70013 0.56804 0.11350  -0.12101 -0.15751 135 PRO A CD  
1059 N N   . TRP A 136 ? 0.62310 0.65080 0.54560 0.09323  -0.09590 -0.17123 136 TRP A N   
1060 C CA  . TRP A 136 ? 0.64587 0.67419 0.58078 0.08920  -0.09104 -0.18150 136 TRP A CA  
1061 C C   . TRP A 136 ? 0.60326 0.61585 0.57981 0.07247  -0.08490 -0.17572 136 TRP A C   
1062 O O   . TRP A 136 ? 0.59857 0.60659 0.57990 0.06627  -0.07444 -0.17320 136 TRP A O   
1063 C CB  . TRP A 136 ? 0.64676 0.68968 0.58696 0.10257  -0.10923 -0.21202 136 TRP A CB  
1064 C CG  . TRP A 136 ? 0.66227 0.70454 0.64579 0.10180  -0.12883 -0.23209 136 TRP A CG  
1065 C CD1 . TRP A 136 ? 0.60894 0.66198 0.59437 0.11231  -0.14764 -0.24596 136 TRP A CD1 
1066 C CD2 . TRP A 136 ? 0.58290 0.61392 0.61519 0.09012  -0.13180 -0.24116 136 TRP A CD2 
1067 N NE1 . TRP A 136 ? 0.62767 0.67802 0.66333 0.10642  -0.16172 -0.26381 136 TRP A NE1 
1068 C CE2 . TRP A 136 ? 0.63295 0.66853 0.69755 0.09244  -0.15160 -0.26012 136 TRP A CE2 
1069 C CE3 . TRP A 136 ? 0.61747 0.63474 0.66945 0.07821  -0.11973 -0.23432 136 TRP A CE3 
1070 C CZ2 . TRP A 136 ? 0.62065 0.64622 0.73756 0.08170  -0.15810 -0.27129 136 TRP A CZ2 
1071 C CZ3 . TRP A 136 ? 0.55737 0.56342 0.65758 0.06918  -0.12666 -0.24432 136 TRP A CZ3 
1072 C CH2 . TRP A 136 ? 0.53443 0.54403 0.66717 0.07018  -0.14489 -0.26203 136 TRP A CH2 
1073 N N   . ILE A 137 ? 0.54190 0.54715 0.54767 0.06568  -0.09050 -0.17262 137 ILE A N   
1074 C CA  . ILE A 137 ? 0.54905 0.53944 0.59023 0.05009  -0.08238 -0.16351 137 ILE A CA  
1075 C C   . ILE A 137 ? 0.55202 0.53230 0.57496 0.04118  -0.06267 -0.13769 137 ILE A C   
1076 O O   . ILE A 137 ? 0.52000 0.49094 0.55522 0.03163  -0.05212 -0.13040 137 ILE A O   
1077 C CB  . ILE A 137 ? 0.58023 0.56889 0.65864 0.04557  -0.09274 -0.16785 137 ILE A CB  
1078 C CG1 . ILE A 137 ? 0.56533 0.56370 0.66826 0.05274  -0.11312 -0.19617 137 ILE A CG1 
1079 C CG2 . ILE A 137 ? 0.55979 0.53354 0.67013 0.02972  -0.08152 -0.15446 137 ILE A CG2 
1080 C CD1 . ILE A 137 ? 0.54489 0.54261 0.69451 0.04561  -0.12267 -0.20268 137 ILE A CD1 
1081 N N   . GLN A 138 ? 0.53086 0.51219 0.52437 0.04484  -0.05826 -0.12401 138 GLN A N   
1082 C CA  . GLN A 138 ? 0.50539 0.47683 0.48080 0.03682  -0.04047 -0.10124 138 GLN A CA  
1083 C C   . GLN A 138 ? 0.55327 0.52792 0.50885 0.03610  -0.02930 -0.09931 138 GLN A C   
1084 O O   . GLN A 138 ? 0.55065 0.51739 0.51125 0.02602  -0.01654 -0.08808 138 GLN A O   
1085 C CB  . GLN A 138 ? 0.50697 0.47730 0.45394 0.04249  -0.03944 -0.08838 138 GLN A CB  
1086 C CG  . GLN A 138 ? 0.52633 0.49412 0.49287 0.04314  -0.04847 -0.08782 138 GLN A CG  
1087 C CD  . GLN A 138 ? 0.60144 0.56425 0.53942 0.04868  -0.04585 -0.07246 138 GLN A CD  
1088 O OE1 . GLN A 138 ? 0.67255 0.63379 0.57464 0.05257  -0.03826 -0.06273 138 GLN A OE1 
1089 N NE2 . GLN A 138 ? 0.51477 0.47462 0.46966 0.04889  -0.05126 -0.06951 138 GLN A NE2 
1090 N N   . ARG A 139 ? 0.54052 0.52873 0.47299 0.04752  -0.03389 -0.11068 139 ARG A N   
1091 C CA  . ARG A 139 ? 0.55252 0.54793 0.46711 0.04779  -0.02265 -0.11018 139 ARG A CA  
1092 C C   . ARG A 139 ? 0.57712 0.56990 0.52108 0.04189  -0.02189 -0.11936 139 ARG A C   
1093 O O   . ARG A 139 ? 0.58504 0.57746 0.52607 0.03581  -0.00914 -0.11176 139 ARG A O   
1094 C CB  . ARG A 139 ? 0.63656 0.64951 0.52225 0.06303  -0.02872 -0.12317 139 ARG A CB  
1095 C CG  . ARG A 139 ? 0.72970 0.74482 0.57835 0.07029  -0.02688 -0.11050 139 ARG A CG  
1096 C CD  . ARG A 139 ? 0.81326 0.84716 0.62672 0.08522  -0.02805 -0.11979 139 ARG A CD  
1097 N NE  . ARG A 139 ? 0.95953 1.00092 0.75947 0.10046  -0.04559 -0.13107 139 ARG A NE  
1098 C CZ  . ARG A 139 ? 0.96867 1.02203 0.78006 0.11141  -0.06329 -0.15744 139 ARG A CZ  
1099 N NH1 . ARG A 139 ? 0.93835 0.99555 0.77514 0.10910  -0.06583 -0.17507 139 ARG A NH1 
1100 N NH2 . ARG A 139 ? 0.91864 0.97997 0.71608 0.12580  -0.07980 -0.16715 139 ARG A NH2 
1101 N N   . LEU A 140 ? 0.57064 0.56125 0.54444 0.04377  -0.03591 -0.13580 140 LEU A N   
1102 C CA  . LEU A 140 ? 0.52678 0.51067 0.53017 0.03859  -0.03617 -0.14304 140 LEU A CA  
1103 C C   . LEU A 140 ? 0.52635 0.49510 0.54495 0.02497  -0.02489 -0.12404 140 LEU A C   
1104 O O   . LEU A 140 ? 0.50805 0.47370 0.53137 0.02077  -0.01672 -0.12025 140 LEU A O   
1105 C CB  . LEU A 140 ? 0.51789 0.49985 0.55215 0.04230  -0.05371 -0.16330 140 LEU A CB  
1106 C CG  . LEU A 140 ? 0.61965 0.59149 0.68724 0.03846  -0.05682 -0.17261 140 LEU A CG  
1107 C CD1 . LEU A 140 ? 0.61172 0.59336 0.66718 0.04759  -0.05647 -0.18631 140 LEU A CD1 
1108 C CD2 . LEU A 140 ? 0.63737 0.60409 0.73984 0.03862  -0.07319 -0.18876 140 LEU A CD2 
1109 N N   . PHE A 141 ? 0.49229 0.45290 0.51819 0.01921  -0.02478 -0.11276 141 PHE A N   
1110 C CA  . PHE A 141 ? 0.49727 0.44489 0.53559 0.00769  -0.01427 -0.09562 141 PHE A CA  
1111 C C   . PHE A 141 ? 0.50406 0.45230 0.51776 0.00395  0.00042  -0.08134 141 PHE A C   
1112 O O   . PHE A 141 ? 0.51951 0.46187 0.54143 -0.00243 0.00828  -0.07451 141 PHE A O   
1113 C CB  . PHE A 141 ? 0.46324 0.40541 0.51150 0.00412  -0.01660 -0.08764 141 PHE A CB  
1114 C CG  . PHE A 141 ? 0.46220 0.39281 0.51994 -0.00619 -0.00543 -0.07048 141 PHE A CG  
1115 C CD1 . PHE A 141 ? 0.44238 0.36457 0.53099 -0.01256 -0.00540 -0.06965 141 PHE A CD1 
1116 C CD2 . PHE A 141 ? 0.46360 0.39128 0.49904 -0.00912 0.00511  -0.05524 141 PHE A CD2 
1117 C CE1 . PHE A 141 ? 0.45886 0.37211 0.55286 -0.02045 0.00519  -0.05398 141 PHE A CE1 
1118 C CE2 . PHE A 141 ? 0.43610 0.35430 0.47904 -0.01718 0.01442  -0.04167 141 PHE A CE2 
1119 C CZ  . PHE A 141 ? 0.46901 0.38113 0.53970 -0.02220 0.01455  -0.04111 141 PHE A CZ  
1120 N N   . LEU A 142 ? 0.47961 0.43493 0.46355 0.00798  0.00406  -0.07664 142 LEU A N   
1121 C CA  . LEU A 142 ? 0.49685 0.45224 0.46027 0.00277  0.01843  -0.06266 142 LEU A CA  
1122 C C   . LEU A 142 ? 0.55952 0.52455 0.52107 0.00324  0.02417  -0.06875 142 LEU A C   
1123 O O   . LEU A 142 ? 0.51605 0.48057 0.47324 -0.00369 0.03556  -0.05886 142 LEU A O   
1124 C CB  . LEU A 142 ? 0.52945 0.48850 0.46197 0.00720  0.02116  -0.05531 142 LEU A CB  
1125 C CG  . LEU A 142 ? 0.50019 0.44857 0.43229 0.00667  0.01751  -0.04600 142 LEU A CG  
1126 C CD1 . LEU A 142 ? 0.51919 0.47089 0.41968 0.01481  0.01669  -0.04101 142 LEU A CD1 
1127 C CD2 . LEU A 142 ? 0.48665 0.42203 0.42552 -0.00418 0.02773  -0.03089 142 LEU A CD2 
1128 N N   . ALA A 143 ? 0.54742 0.52210 0.51400 0.01179  0.01581  -0.08626 143 ALA A N   
1129 C CA  . ALA A 143 ? 0.57990 0.56525 0.54721 0.01408  0.02028  -0.09417 143 ALA A CA  
1130 C C   . ALA A 143 ? 0.58298 0.55875 0.57716 0.00908  0.01993  -0.09436 143 ALA A C   
1131 O O   . ALA A 143 ? 0.59832 0.58186 0.59440 0.01001  0.02485  -0.09787 143 ALA A O   
1132 C CB  . ALA A 143 ? 0.58398 0.58304 0.54648 0.02683  0.01080  -0.11459 143 ALA A CB  
1133 N N   . LEU A 144 ? 0.52558 0.48569 0.54042 0.00453  0.01452  -0.09037 144 LEU A N   
1134 C CA  . LEU A 144 ? 0.53911 0.48845 0.57657 0.00051  0.01488  -0.08791 144 LEU A CA  
1135 C C   . LEU A 144 ? 0.52322 0.47188 0.55266 -0.00668 0.02710  -0.07316 144 LEU A C   
1136 O O   . LEU A 144 ? 0.52380 0.47389 0.53661 -0.01147 0.03450  -0.06239 144 LEU A O   
1137 C CB  . LEU A 144 ? 0.46385 0.39772 0.52430 -0.00358 0.00863  -0.08474 144 LEU A CB  
1138 C CG  . LEU A 144 ? 0.50763 0.44081 0.58487 0.00209  -0.00516 -0.10123 144 LEU A CG  
1139 C CD1 . LEU A 144 ? 0.51982 0.44098 0.61967 -0.00429 -0.00861 -0.09534 144 LEU A CD1 
1140 C CD2 . LEU A 144 ? 0.51479 0.44612 0.60799 0.00781  -0.01153 -0.11550 144 LEU A CD2 
1141 N N   . PRO A 145 ? 0.57465 0.52085 0.61589 -0.00683 0.02853  -0.07319 145 PRO A N   
1142 C CA  . PRO A 145 ? 0.58127 0.52795 0.61668 -0.01298 0.03820  -0.06111 145 PRO A CA  
1143 C C   . PRO A 145 ? 0.50888 0.44247 0.54448 -0.02055 0.04165  -0.04654 145 PRO A C   
1144 O O   . PRO A 145 ? 0.48181 0.40394 0.53025 -0.02125 0.03677  -0.04466 145 PRO A O   
1145 C CB  . PRO A 145 ? 0.57220 0.51622 0.62312 -0.00909 0.03532  -0.06504 145 PRO A CB  
1146 C CG  . PRO A 145 ? 0.57505 0.52230 0.63523 -0.00006 0.02619  -0.08171 145 PRO A CG  
1147 C CD  . PRO A 145 ? 0.60683 0.54965 0.66692 -0.00023 0.02043  -0.08518 145 PRO A CD  
1148 N N   . LEU A 146 ? 0.52979 0.41369 0.61339 0.03784  -0.14076 -0.11474 146 LEU A N   
1149 C CA  . LEU A 146 ? 0.56006 0.42088 0.61281 0.03395  -0.13254 -0.11878 146 LEU A CA  
1150 C C   . LEU A 146 ? 0.59672 0.43129 0.59740 0.03885  -0.13495 -0.11478 146 LEU A C   
1151 O O   . LEU A 146 ? 0.56679 0.38651 0.54401 0.03814  -0.11624 -0.11061 146 LEU A O   
1152 C CB  . LEU A 146 ? 0.52687 0.38655 0.58855 0.02664  -0.14382 -0.13434 146 LEU A CB  
1153 C CG  . LEU A 146 ? 0.60945 0.47869 0.71062 0.01881  -0.12912 -0.13595 146 LEU A CG  
1154 C CD1 . LEU A 146 ? 0.60118 0.46968 0.71879 0.00804  -0.14255 -0.15296 146 LEU A CD1 
1155 C CD2 . LEU A 146 ? 0.52300 0.37253 0.60883 0.02044  -0.10491 -0.13106 146 LEU A CD2 
1156 N N   . PHE A 147 ? 0.57230 0.40282 0.55603 0.04467  -0.15705 -0.11369 147 PHE A N   
1157 C CA  . PHE A 147 ? 0.64829 0.45184 0.57688 0.04912  -0.15967 -0.10615 147 PHE A CA  
1158 C C   . PHE A 147 ? 0.61880 0.41169 0.53985 0.05093  -0.14052 -0.09050 147 PHE A C   
1159 O O   . PHE A 147 ? 0.66383 0.43426 0.54236 0.05027  -0.12953 -0.08320 147 PHE A O   
1160 C CB  . PHE A 147 ? 0.67165 0.47562 0.58582 0.05708  -0.19042 -0.10366 147 PHE A CB  
1161 C CG  . PHE A 147 ? 0.66220 0.47152 0.60036 0.06808  -0.19719 -0.08985 147 PHE A CG  
1162 C CD1 . PHE A 147 ? 0.65207 0.49019 0.64763 0.07054  -0.20135 -0.09482 147 PHE A CD1 
1163 C CD2 . PHE A 147 ? 0.74307 0.52580 0.64608 0.07615  -0.19722 -0.07205 147 PHE A CD2 
1164 C CE1 . PHE A 147 ? 0.68437 0.52398 0.70230 0.08233  -0.20458 -0.08561 147 PHE A CE1 
1165 C CE2 . PHE A 147 ? 0.68781 0.46797 0.61469 0.08730  -0.20160 -0.06078 147 PHE A CE2 
1166 C CZ  . PHE A 147 ? 0.67550 0.48389 0.66020 0.09116  -0.20504 -0.06931 147 PHE A CZ  
1167 N N   . ILE A 148 ? 0.60452 0.41393 0.56547 0.05115  -0.13482 -0.08673 148 ILE A N   
1168 C CA  . ILE A 148 ? 0.61229 0.41429 0.57081 0.04799  -0.11632 -0.07625 148 ILE A CA  
1169 C C   . ILE A 148 ? 0.59799 0.40726 0.55777 0.04001  -0.09354 -0.07646 148 ILE A C   
1170 O O   . ILE A 148 ? 0.57776 0.37461 0.51565 0.03634  -0.07804 -0.06821 148 ILE A O   
1171 C CB  . ILE A 148 ? 0.56747 0.38568 0.56509 0.04882  -0.11679 -0.07718 148 ILE A CB  
1172 C CG1 . ILE A 148 ? 0.65082 0.45900 0.65111 0.06079  -0.13606 -0.07482 148 ILE A CG1 
1173 C CG2 . ILE A 148 ? 0.58843 0.40277 0.58660 0.04045  -0.09812 -0.07128 148 ILE A CG2 
1174 C CD1 . ILE A 148 ? 0.63365 0.40558 0.59763 0.06560  -0.13717 -0.06025 148 ILE A CD1 
1175 N N   . ARG A 149 ? 0.55147 0.38199 0.54065 0.03786  -0.09016 -0.08392 149 ARG A N   
1176 C CA  . ARG A 149 ? 0.54683 0.38613 0.54420 0.03438  -0.06950 -0.08152 149 ARG A CA  
1177 C C   . ARG A 149 ? 0.60497 0.42055 0.56410 0.03607  -0.05931 -0.08374 149 ARG A C   
1178 O O   . ARG A 149 ? 0.58551 0.40298 0.54120 0.03479  -0.03887 -0.07707 149 ARG A O   
1179 C CB  . ARG A 149 ? 0.51658 0.37614 0.55033 0.03379  -0.06889 -0.08601 149 ARG A CB  
1180 C CG  . ARG A 149 ? 0.47260 0.36238 0.54174 0.03076  -0.06906 -0.08086 149 ARG A CG  
1181 C CD  . ARG A 149 ? 0.50164 0.40887 0.60265 0.02986  -0.06703 -0.08106 149 ARG A CD  
1182 N NE  . ARG A 149 ? 0.42939 0.33954 0.54401 0.02911  -0.08192 -0.09010 149 ARG A NE  
1183 C CZ  . ARG A 149 ? 0.49113 0.40408 0.62697 0.02614  -0.08293 -0.09411 149 ARG A CZ  
1184 N NH1 . ARG A 149 ? 0.40932 0.31526 0.55268 0.02553  -0.06965 -0.08985 149 ARG A NH1 
1185 N NH2 . ARG A 149 ? 0.43243 0.35532 0.58683 0.02381  -0.09644 -0.10207 149 ARG A NH2 
1186 N N   . HIS A 150 ? 0.60579 0.40208 0.53597 0.03837  -0.07305 -0.09418 150 HIS A N   
1187 C CA  . HIS A 150 ? 0.68540 0.45700 0.56861 0.03930  -0.06319 -0.09955 150 HIS A CA  
1188 C C   . HIS A 150 ? 0.66284 0.42201 0.51271 0.03887  -0.05131 -0.08523 150 HIS A C   
1189 O O   . HIS A 150 ? 0.67575 0.42958 0.51028 0.03824  -0.02700 -0.08319 150 HIS A O   
1190 C CB  . HIS A 150 ? 0.69097 0.44699 0.54170 0.03947  -0.08606 -0.11365 150 HIS A CB  
1191 C CG  . HIS A 150 ? 0.76759 0.52453 0.63779 0.03588  -0.08869 -0.13274 150 HIS A CG  
1192 N ND1 . HIS A 150 ? 0.85265 0.62245 0.74948 0.03227  -0.11246 -0.14156 150 HIS A ND1 
1193 C CD2 . HIS A 150 ? 0.78986 0.53436 0.66028 0.03493  -0.06878 -0.14482 150 HIS A CD2 
1194 C CE1 . HIS A 150 ? 0.85357 0.61683 0.76481 0.02650  -0.10750 -0.15817 150 HIS A CE1 
1195 N NE2 . HIS A 150 ? 0.94190 0.68691 0.83681 0.02908  -0.08098 -0.16066 150 HIS A NE2 
1196 N N   . ARG A 151 ? 0.61879 0.37189 0.45952 0.03955  -0.06629 -0.07451 151 ARG A N   
1197 C CA  . ARG A 151 ? 0.71176 0.44680 0.52056 0.03731  -0.05453 -0.05841 151 ARG A CA  
1198 C C   . ARG A 151 ? 0.67996 0.43179 0.52130 0.02970  -0.03064 -0.05030 151 ARG A C   
1199 O O   . ARG A 151 ? 0.71899 0.46297 0.53985 0.02497  -0.00910 -0.04133 151 ARG A O   
1200 C CB  . ARG A 151 ? 0.72752 0.44736 0.52499 0.04162  -0.07582 -0.04714 151 ARG A CB  
1201 C CG  . ARG A 151 ? 0.85726 0.57085 0.63097 0.04993  -0.10494 -0.05333 151 ARG A CG  
1202 C CD  . ARG A 151 ? 0.95689 0.64478 0.69010 0.05703  -0.11952 -0.03463 151 ARG A CD  
1203 N NE  . ARG A 151 ? 1.03145 0.71784 0.80008 0.06231  -0.12781 -0.02423 151 ARG A NE  
1204 C CZ  . ARG A 151 ? 1.07492 0.74862 0.83446 0.07469  -0.15093 -0.01186 151 ARG A CZ  
1205 N NH1 . ARG A 151 ? 1.05695 0.72365 0.77176 0.08221  -0.17253 -0.00658 151 ARG A NH1 
1206 N NH2 . ARG A 151 ? 1.00337 0.67201 0.79958 0.08039  -0.15284 -0.00514 151 ARG A NH2 
1207 N N   . ILE A 152 ? 0.66443 0.44284 0.55601 0.02724  -0.03418 -0.05311 152 ILE A N   
1208 C CA  . ILE A 152 ? 0.60679 0.40938 0.53117 0.01856  -0.01596 -0.04695 152 ILE A CA  
1209 C C   . ILE A 152 ? 0.62614 0.44174 0.55487 0.02010  0.00630  -0.04745 152 ILE A C   
1210 O O   . ILE A 152 ? 0.64905 0.47222 0.57971 0.01394  0.02692  -0.03880 152 ILE A O   
1211 C CB  . ILE A 152 ? 0.58391 0.41582 0.55395 0.01631  -0.02586 -0.05148 152 ILE A CB  
1212 C CG1 . ILE A 152 ? 0.60925 0.42872 0.58000 0.01470  -0.04078 -0.05206 152 ILE A CG1 
1213 C CG2 . ILE A 152 ? 0.56700 0.43315 0.57065 0.00762  -0.01043 -0.04615 152 ILE A CG2 
1214 C CD1 . ILE A 152 ? 0.54402 0.39113 0.55204 0.01347  -0.04911 -0.05984 152 ILE A CD1 
1215 N N   . ALA A 153 ? 0.62385 0.44151 0.55787 0.02838  0.00403  -0.05794 153 ALA A N   
1216 C CA  . ALA A 153 ? 0.63357 0.46030 0.57802 0.03356  0.02674  -0.05977 153 ALA A CA  
1217 C C   . ALA A 153 ? 0.69742 0.50008 0.59540 0.03465  0.04564  -0.06081 153 ALA A C   
1218 O O   . ALA A 153 ? 0.67859 0.49491 0.58829 0.03557  0.07188  -0.05562 153 ALA A O   
1219 C CB  . ALA A 153 ? 0.59227 0.41620 0.55116 0.04132  0.02059  -0.07193 153 ALA A CB  
1220 N N   . ALA A 154 ? 0.68242 0.45278 0.52749 0.03503  0.03299  -0.06669 154 ALA A N   
1221 C CA  . ALA A 154 ? 0.77384 0.52061 0.56383 0.03528  0.05097  -0.06681 154 ALA A CA  
1222 C C   . ALA A 154 ? 0.75566 0.50763 0.54324 0.02674  0.06939  -0.04738 154 ALA A C   
1223 O O   . ALA A 154 ? 0.78546 0.53764 0.55751 0.02606  0.09886  -0.04437 154 ALA A O   
1224 C CB  . ALA A 154 ? 0.78246 0.49837 0.51342 0.03662  0.02787  -0.07367 154 ALA A CB  
1225 N N   . ARG A 155 ? 0.72321 0.47861 0.52827 0.01923  0.05471  -0.03528 155 ARG A N   
1226 C CA  . ARG A 155 ? 0.74555 0.50294 0.55397 0.00717  0.07210  -0.01800 155 ARG A CA  
1227 C C   . ARG A 155 ? 0.76151 0.56075 0.62569 0.00164  0.09425  -0.01578 155 ARG A C   
1228 O O   . ARG A 155 ? 0.79569 0.60261 0.66001 -0.00646 0.12079  -0.00572 155 ARG A O   
1229 C CB  . ARG A 155 ? 0.72185 0.46722 0.53828 0.00050  0.05123  -0.00952 155 ARG A CB  
1230 C CG  . ARG A 155 ? 0.75764 0.49950 0.58229 -0.01568 0.06823  0.00658  155 ARG A CG  
1231 C CD  . ARG A 155 ? 0.88100 0.60027 0.65665 -0.01923 0.09323  0.02022  155 ARG A CD  
1232 N NE  . ARG A 155 ? 0.99476 0.66850 0.72133 -0.01929 0.08291  0.03596  155 ARG A NE  
1233 C CZ  . ARG A 155 ? 0.95556 0.60947 0.69103 -0.03160 0.08501  0.05120  155 ARG A CZ  
1234 N NH1 . ARG A 155 ? 1.02767 0.70512 0.81702 -0.04847 0.09629  0.04965  155 ARG A NH1 
1235 N NH2 . ARG A 155 ? 1.02009 0.62888 0.70983 -0.02714 0.07466  0.06849  155 ARG A NH2 
1236 N N   . MET A 156 ? 0.70474 0.53468 0.61818 0.00577  0.08356  -0.02302 156 MET A N   
1237 C CA  . MET A 156 ? 0.69547 0.57181 0.66489 0.00264  0.09939  -0.01822 156 MET A CA  
1238 C C   . MET A 156 ? 0.73055 0.61542 0.70086 0.01304  0.12864  -0.01987 156 MET A C   
1239 O O   . MET A 156 ? 0.74853 0.66672 0.75276 0.00835  0.15105  -0.01090 156 MET A O   
1240 C CB  . MET A 156 ? 0.58094 0.48578 0.59421 0.00691  0.07984  -0.02256 156 MET A CB  
1241 C CG  . MET A 156 ? 0.64952 0.56196 0.67714 -0.00629 0.05969  -0.02116 156 MET A CG  
1242 S SD  . MET A 156 ? 0.59926 0.54367 0.66599 -0.00113 0.03876  -0.02597 156 MET A SD  
1243 C CE  . MET A 156 ? 0.51733 0.51273 0.63292 0.00512  0.05613  -0.01585 156 MET A CE  
1244 N N   . ARG A 157 ? 0.71626 0.57261 0.65208 0.02657  0.12970  -0.03299 157 ARG A N   
1245 C CA  . ARG A 157 ? 0.77988 0.63598 0.70996 0.03770  0.16092  -0.03911 157 ARG A CA  
1246 C C   . ARG A 157 ? 0.85313 0.69911 0.74574 0.02964  0.18771  -0.03151 157 ARG A C   
1247 O O   . ARG A 157 ? 0.89870 0.77086 0.81752 0.03182  0.21977  -0.02666 157 ARG A O   
1248 C CB  . ARG A 157 ? 0.74364 0.56417 0.63781 0.05002  0.15465  -0.05965 157 ARG A CB  
1249 C CG  . ARG A 157 ? 0.74402 0.57567 0.68350 0.05901  0.13873  -0.06561 157 ARG A CG  
1250 C CD  . ARG A 157 ? 0.82131 0.61724 0.73392 0.06915  0.14015  -0.08828 157 ARG A CD  
1251 N NE  . ARG A 157 ? 0.88244 0.64236 0.73224 0.06200  0.11872  -0.10110 157 ARG A NE  
1252 C CZ  . ARG A 157 ? 0.82726 0.58066 0.67784 0.05748  0.08615  -0.10520 157 ARG A CZ  
1253 N NH1 . ARG A 157 ? 0.74787 0.52501 0.65265 0.05788  0.07283  -0.09758 157 ARG A NH1 
1254 N NH2 . ARG A 157 ? 0.79200 0.51800 0.58777 0.05262  0.06656  -0.11617 157 ARG A NH2 
1255 N N   . ALA A 158 ? 0.86604 0.67592 0.69935 0.02098  0.17594  -0.02799 158 ALA A N   
1256 C CA  . ALA A 158 ? 0.94624 0.74301 0.73887 0.01163  0.20156  -0.01584 158 ALA A CA  
1257 C C   . ALA A 158 ? 0.94064 0.77205 0.78477 -0.00446 0.21571  0.00245  158 ALA A C   
1258 O O   . ALA A 158 ? 0.96049 0.80527 0.80625 -0.01043 0.25025  0.01119  158 ALA A O   
1259 C CB  . ALA A 158 ? 0.96486 0.71558 0.68554 0.00723  0.18133  -0.01056 158 ALA A CB  
1260 N N   . ASP A 159 ? 0.86599 0.71401 0.75312 -0.01328 0.19043  0.00669  159 ASP A N   
1261 C CA  . ASP A 159 ? 0.87065 0.75396 0.80958 -0.03217 0.20003  0.01960  159 ASP A CA  
1262 C C   . ASP A 159 ? 0.89434 0.83459 0.89563 -0.02761 0.22338  0.01976  159 ASP A C   
1263 O O   . ASP A 159 ? 0.84211 0.81313 0.87539 -0.04199 0.24704  0.03089  159 ASP A O   
1264 C CB  . ASP A 159 ? 0.84642 0.73563 0.81454 -0.04152 0.16723  0.01811  159 ASP A CB  
1265 C CG  . ASP A 159 ? 0.88461 0.72311 0.80686 -0.04993 0.15146  0.02378  159 ASP A CG  
1266 O OD1 . ASP A 159 ? 0.88566 0.68841 0.75628 -0.05189 0.16625  0.03428  159 ASP A OD1 
1267 O OD2 . ASP A 159 ? 0.85265 0.68702 0.79008 -0.05326 0.12526  0.01874  159 ASP A OD2 
1268 N N   A SER A 160 ? 0.85176 0.80738 0.87517 -0.00740 0.21750  0.00894  160 SER A N   
1269 N N   B SER A 160 ? 0.85069 0.80650 0.87427 -0.00745 0.21766  0.00900  160 SER A N   
1270 C CA  A SER A 160 ? 0.82107 0.82962 0.90699 0.00280  0.23888  0.01154  160 SER A CA  
1271 C CA  B SER A 160 ? 0.82200 0.83089 0.90818 0.00252  0.23912  0.01173  160 SER A CA  
1272 C C   A SER A 160 ? 0.86314 0.86613 0.92951 0.01199  0.28077  0.00982  160 SER A C   
1273 C C   B SER A 160 ? 0.86419 0.86720 0.93102 0.01281  0.28062  0.00941  160 SER A C   
1274 O O   A SER A 160 ? 0.86292 0.91460 0.98414 0.01450  0.30741  0.01713  160 SER A O   
1275 O O   B SER A 160 ? 0.86201 0.91371 0.98466 0.01688  0.30677  0.01608  160 SER A O   
1276 C CB  A SER A 160 ? 0.77174 0.79057 0.88583 0.02311  0.22113  0.00366  160 SER A CB  
1277 C CB  B SER A 160 ? 0.77848 0.80021 0.89573 0.02205  0.22040  0.00449  160 SER A CB  
1278 O OG  A SER A 160 ? 0.69093 0.77179 0.88067 0.02975  0.22878  0.01351  160 SER A OG  
1279 O OG  B SER A 160 ? 0.71183 0.76102 0.86440 0.01177  0.18985  0.00986  160 SER A OG  
1280 N N   . LYS A 161 ? 0.91308 0.86106 0.90241 0.01733  0.28732  -0.00029 161 LYS A N   
1281 C CA  . LYS A 161 ? 0.95768 0.89706 0.91710 0.02529  0.32950  -0.00488 161 LYS A CA  
1282 C C   . LYS A 161 ? 0.99176 0.95016 0.95539 0.00528  0.35810  0.01327  161 LYS A C   
1283 O O   . LYS A 161 ? 1.03035 1.01691 1.01643 0.01000  0.39901  0.01519  161 LYS A O   
1284 C CB  . LYS A 161 ? 0.99957 0.87675 0.86687 0.03233  0.32517  -0.02106 161 LYS A CB  
1285 N N   . ALA A 162 ? 1.04374 0.88045 1.06363 0.05474  0.03552  0.12333  162 ALA A N   
1286 C CA  . ALA A 162 ? 1.05677 0.88436 1.11616 0.05103  0.04948  0.15694  162 ALA A CA  
1287 C C   . ALA A 162 ? 1.05318 0.90328 1.17501 0.03363  0.05853  0.15989  162 ALA A C   
1288 O O   . ALA A 162 ? 1.00650 0.87297 1.15934 0.02055  0.04141  0.13067  162 ALA A O   
1289 C CB  . ALA A 162 ? 1.03103 0.84017 1.11903 0.04863  0.02967  0.15536  162 ALA A CB  
1290 N N   . GLU A 170 ? 1.01649 1.01088 1.04488 0.03180  0.13647  0.11513  170 GLU A N   
1291 C CA  . GLU A 170 ? 0.94430 0.95734 1.02928 0.01770  0.14198  0.12221  170 GLU A CA  
1292 C C   . GLU A 170 ? 0.99158 1.01939 1.09864 0.00429  0.11643  0.09426  170 GLU A C   
1293 O O   . GLU A 170 ? 1.02392 1.05076 1.17032 -0.00669 0.10036  0.08831  170 GLU A O   
1294 C CB  . GLU A 170 ? 0.94330 0.94861 1.07974 0.01141  0.15102  0.14759  170 GLU A CB  
1295 N N   . ILE A 171 ? 0.88241 0.92268 0.96333 0.00671  0.11283  0.07736  171 ILE A N   
1296 C CA  . ILE A 171 ? 0.76908 0.82239 0.86140 -0.00279 0.09211  0.05313  171 ILE A CA  
1297 C C   . ILE A 171 ? 0.73172 0.80032 0.87284 -0.01448 0.09084  0.05850  171 ILE A C   
1298 O O   . ILE A 171 ? 0.71804 0.79692 0.87013 -0.01358 0.10730  0.07250  171 ILE A O   
1299 C CB  . ILE A 171 ? 0.70771 0.76872 0.76094 0.00441  0.09057  0.03684  171 ILE A CB  
1300 C CG1 . ILE A 171 ? 0.70166 0.74594 0.71276 0.01725  0.08898  0.03098  171 ILE A CG1 
1301 C CG2 . ILE A 171 ? 0.63928 0.71213 0.70053 -0.00340 0.07277  0.01523  171 ILE A CG2 
1302 C CD1 . ILE A 171 ? 0.62688 0.67673 0.60682 0.02670  0.08974  0.01886  171 ILE A CD1 
1303 N N   . MET A 172 ? 0.67157 0.74053 0.84320 -0.02429 0.06971  0.04605  172 MET A N   
1304 C CA  . MET A 172 ? 0.67472 0.75619 0.89198 -0.03430 0.06040  0.04573  172 MET A CA  
1305 C C   . MET A 172 ? 0.58173 0.67963 0.77918 -0.03355 0.05864  0.03523  172 MET A C   
1306 O O   . MET A 172 ? 0.59518 0.69435 0.75156 -0.02853 0.05374  0.01902  172 MET A O   
1307 C CB  . MET A 172 ? 0.63128 0.70634 0.87489 -0.04141 0.03307  0.02862  172 MET A CB  
1308 C CG  . MET A 172 ? 0.63951 0.72300 0.93438 -0.05038 0.01672  0.02610  172 MET A CG  
1309 S SD  . MET A 172 ? 0.80808 0.88936 1.18105 -0.05740 0.02816  0.05534  172 MET A SD  
1310 C CE  . MET A 172 ? 0.58631 0.64794 0.98312 -0.05987 0.01021  0.04804  172 MET A CE  
1311 N N   . ASP A 173 ? 0.57278 0.68325 0.80498 -0.03845 0.06326  0.04590  173 ASP A N   
1312 C CA  . ASP A 173 ? 0.49820 0.62432 0.71926 -0.03841 0.06062  0.03859  173 ASP A CA  
1313 C C   . ASP A 173 ? 0.49425 0.62298 0.72146 -0.04358 0.03198  0.01882  173 ASP A C   
1314 O O   . ASP A 173 ? 0.51268 0.63160 0.75816 -0.04733 0.01346  0.00985  173 ASP A O   
1315 C CB  . ASP A 173 ? 0.46066 0.59846 0.71885 -0.04068 0.07701  0.05817  173 ASP A CB  
1316 C CG  . ASP A 173 ? 0.45570 0.60744 0.69034 -0.03619 0.08548  0.05597  173 ASP A CG  
1317 O OD1 . ASP A 173 ? 0.43398 0.58741 0.62932 -0.03254 0.07661  0.03979  173 ASP A OD1 
1318 O OD2 . ASP A 173 ? 0.45713 0.61831 0.71741 -0.03607 0.10195  0.07113  173 ASP A OD2 
1319 N N   . VAL A 174 ? 0.44406 0.58504 0.65479 -0.04231 0.02793  0.01207  174 VAL A N   
1320 C CA  . VAL A 174 ? 0.42589 0.56769 0.62928 -0.04346 0.00223  -0.00587 174 VAL A CA  
1321 C C   . VAL A 174 ? 0.42605 0.56840 0.68256 -0.05083 -0.01737 -0.00411 174 VAL A C   
1322 O O   . VAL A 174 ? 0.39502 0.54328 0.69845 -0.05592 -0.00769 0.01331  174 VAL A O   
1323 C CB  . VAL A 174 ? 0.41835 0.57218 0.58977 -0.03891 0.00520  -0.00973 174 VAL A CB  
1324 C CG1 . VAL A 174 ? 0.42971 0.58296 0.56019 -0.03157 0.02292  -0.01180 174 VAL A CG1 
1325 C CG2 . VAL A 174 ? 0.43175 0.59967 0.63482 -0.04245 0.01249  0.00513  174 VAL A CG2 
1326 N N   . ASN A 175 ? 0.44477 0.58004 0.69485 -0.04999 -0.04596 -0.02333 175 ASN A N   
1327 C CA  . ASN A 175 ? 0.46285 0.59696 0.76003 -0.05481 -0.07287 -0.02724 175 ASN A CA  
1328 C C   . ASN A 175 ? 0.47071 0.61602 0.75721 -0.05277 -0.08138 -0.02793 175 ASN A C   
1329 O O   . ASN A 175 ? 0.47439 0.62024 0.70576 -0.04514 -0.08433 -0.03871 175 ASN A O   
1330 C CB  . ASN A 175 ? 0.46300 0.58119 0.75460 -0.05202 -0.10349 -0.05058 175 ASN A CB  
1331 C CG  . ASN A 175 ? 0.53008 0.64440 0.86985 -0.05490 -0.13802 -0.05894 175 ASN A CG  
1332 O OD1 . ASN A 175 ? 0.54322 0.65910 0.86207 -0.04986 -0.15795 -0.06927 175 ASN A OD1 
1333 N ND2 . ASN A 175 ? 0.49640 0.60440 0.90361 -0.06221 -0.14651 -0.05402 175 ASN A ND2 
1334 N N   . PRO A 176 ? 0.44896 0.60308 0.78960 -0.05891 -0.08422 -0.01519 176 PRO A N   
1335 C CA  . PRO A 176 ? 0.46063 0.62564 0.79351 -0.05696 -0.09172 -0.01382 176 PRO A CA  
1336 C C   . PRO A 176 ? 0.46884 0.62503 0.76570 -0.04956 -0.12579 -0.03465 176 PRO A C   
1337 O O   . PRO A 176 ? 0.45255 0.61452 0.70709 -0.04331 -0.12484 -0.03535 176 PRO A O   
1338 C CB  . PRO A 176 ? 0.45252 0.62527 0.86465 -0.06550 -0.09338 0.00148  176 PRO A CB  
1339 C CG  . PRO A 176 ? 0.47648 0.64736 0.92394 -0.07048 -0.06822 0.01637  176 PRO A CG  
1340 C CD  . PRO A 176 ? 0.44191 0.59718 0.85631 -0.06743 -0.07652 0.00149  176 PRO A CD  
1341 N N   . GLN A 177 ? 0.44994 0.59105 0.76193 -0.04863 -0.15618 -0.05151 177 GLN A N   
1342 C CA  . GLN A 177 ? 0.47500 0.60432 0.74389 -0.03794 -0.18993 -0.07357 177 GLN A CA  
1343 C C   . GLN A 177 ? 0.48784 0.61227 0.67521 -0.02708 -0.17686 -0.08390 177 GLN A C   
1344 O O   . GLN A 177 ? 0.52714 0.64891 0.66153 -0.01611 -0.18670 -0.09153 177 GLN A O   
1345 C CB  . GLN A 177 ? 0.49105 0.60365 0.79891 -0.03804 -0.22782 -0.09207 177 GLN A CB  
1346 N N   . ALA A 178 ? 0.47924 0.60190 0.65720 -0.02906 -0.15389 -0.08287 178 ALA A N   
1347 C CA  . ALA A 178 ? 0.54020 0.65948 0.65107 -0.01932 -0.13881 -0.09131 178 ALA A CA  
1348 C C   . ALA A 178 ? 0.49663 0.63036 0.57565 -0.01617 -0.11528 -0.07736 178 ALA A C   
1349 O O   . ALA A 178 ? 0.47731 0.60876 0.50179 -0.00521 -0.11225 -0.08382 178 ALA A O   
1350 C CB  . ALA A 178 ? 0.53259 0.64766 0.64911 -0.02298 -0.11971 -0.09097 178 ALA A CB  
1351 N N   . VAL A 179 ? 0.49095 0.63923 0.60590 -0.02472 -0.09752 -0.05770 179 VAL A N   
1352 C CA  . VAL A 179 ? 0.46382 0.62614 0.55902 -0.02223 -0.07814 -0.04488 179 VAL A CA  
1353 C C   . VAL A 179 ? 0.45543 0.61778 0.52864 -0.01523 -0.09834 -0.04739 179 VAL A C   
1354 O O   . VAL A 179 ? 0.47161 0.63586 0.49888 -0.00616 -0.08952 -0.04641 179 VAL A O   
1355 C CB  . VAL A 179 ? 0.47613 0.65230 0.61756 -0.03135 -0.05880 -0.02592 179 VAL A CB  
1356 C CG1 . VAL A 179 ? 0.38515 0.57573 0.51591 -0.02881 -0.04545 -0.01443 179 VAL A CG1 
1357 C CG2 . VAL A 179 ? 0.42883 0.60300 0.57465 -0.03392 -0.03567 -0.02207 179 VAL A CG2 
1358 N N   . VAL A 180 ? 0.45064 0.60991 0.55869 -0.01848 -0.12615 -0.04960 180 VAL A N   
1359 C CA  . VAL A 180 ? 0.49224 0.64907 0.57877 -0.01051 -0.14988 -0.05192 180 VAL A CA  
1360 C C   . VAL A 180 ? 0.54331 0.68431 0.55975 0.00509  -0.16244 -0.06908 180 VAL A C   
1361 O O   . VAL A 180 ? 0.57702 0.71840 0.54607 0.01593  -0.16009 -0.06487 180 VAL A O   
1362 C CB  . VAL A 180 ? 0.52281 0.67636 0.66627 -0.01625 -0.18270 -0.05441 180 VAL A CB  
1363 C CG1 . VAL A 180 ? 0.53829 0.68387 0.65150 -0.00503 -0.21486 -0.06084 180 VAL A CG1 
1364 C CG2 . VAL A 180 ? 0.51734 0.68833 0.72801 -0.02941 -0.16514 -0.03426 180 VAL A CG2 
1365 N N   . ASP A 181 ? 0.53464 0.66091 0.54379 0.00759  -0.17456 -0.08780 181 ASP A N   
1366 C CA  . ASP A 181 ? 0.61641 0.72613 0.55768 0.02444  -0.18543 -0.10641 181 ASP A CA  
1367 C C   . ASP A 181 ? 0.62376 0.73995 0.51363 0.03216  -0.15030 -0.09765 181 ASP A C   
1368 O O   . ASP A 181 ? 0.62860 0.73803 0.45958 0.04787  -0.15168 -0.10000 181 ASP A O   
1369 C CB  . ASP A 181 ? 0.63022 0.72478 0.58077 0.02447  -0.19977 -0.12780 181 ASP A CB  
1370 C CG  . ASP A 181 ? 0.82129 0.90098 0.70087 0.04190  -0.19859 -0.14622 181 ASP A CG  
1371 O OD1 . ASP A 181 ? 0.93501 0.99813 0.77509 0.05702  -0.22848 -0.16383 181 ASP A OD1 
1372 O OD2 . ASP A 181 ? 0.88675 0.97012 0.75028 0.04181  -0.16857 -0.14396 181 ASP A OD2 
1373 N N   . ALA A 182 ? 0.57781 0.70609 0.49058 0.02253  -0.11873 -0.08674 182 ALA A N   
1374 C CA  . ALA A 182 ? 0.59582 0.73063 0.47332 0.02898  -0.08663 -0.07868 182 ALA A CA  
1375 C C   . ALA A 182 ? 0.56791 0.71475 0.43516 0.03228  -0.07659 -0.05989 182 ALA A C   
1376 O O   . ALA A 182 ? 0.60561 0.75112 0.42752 0.04488  -0.06311 -0.05582 182 ALA A O   
1377 C CB  . ALA A 182 ? 0.57338 0.71638 0.48238 0.01865  -0.06128 -0.07312 182 ALA A CB  
1378 N N   . MET A 183 ? 0.55449 0.71304 0.46633 0.02169  -0.08144 -0.04705 183 MET A N   
1379 C CA  . MET A 183 ? 0.54059 0.71100 0.45001 0.02394  -0.07309 -0.02886 183 MET A CA  
1380 C C   . MET A 183 ? 0.60655 0.76644 0.47360 0.03730  -0.09679 -0.03063 183 MET A C   
1381 O O   . MET A 183 ? 0.62082 0.78617 0.46515 0.04475  -0.08612 -0.01562 183 MET A O   
1382 C CB  . MET A 183 ? 0.46647 0.65154 0.43732 0.00988  -0.07205 -0.01641 183 MET A CB  
1383 C CG  . MET A 183 ? 0.41194 0.60430 0.41690 -0.00027 -0.04978 -0.01469 183 MET A CG  
1384 S SD  . MET A 183 ? 0.43318 0.64467 0.49409 -0.01090 -0.03426 0.00307  183 MET A SD  
1385 C CE  . MET A 183 ? 0.39231 0.61478 0.43376 -0.00350 -0.02050 0.01689  183 MET A CE  
1386 N N   . GLU A 184 ? 0.58768 0.73116 0.44334 0.04186  -0.12983 -0.04865 184 GLU A N   
1387 C CA  . GLU A 184 ? 0.62054 0.74953 0.42593 0.05829  -0.15636 -0.05368 184 GLU A CA  
1388 C C   . GLU A 184 ? 0.67217 0.78573 0.40167 0.07774  -0.14841 -0.06452 184 GLU A C   
1389 O O   . GLU A 184 ? 0.74000 0.84546 0.41278 0.09498  -0.15138 -0.05870 184 GLU A O   
1390 C CB  . GLU A 184 ? 0.65277 0.76985 0.48653 0.05579  -0.20119 -0.06968 184 GLU A CB  
1391 C CG  . GLU A 184 ? 0.63937 0.77189 0.54868 0.03909  -0.20771 -0.05577 184 GLU A CG  
1392 C CD  . GLU A 184 ? 0.70937 0.83050 0.65015 0.03903  -0.25448 -0.06780 184 GLU A CD  
1393 O OE1 . GLU A 184 ? 0.71124 0.81293 0.63352 0.04720  -0.28322 -0.09102 184 GLU A OE1 
1394 O OE2 . GLU A 184 ? 0.67668 0.80806 0.66532 0.03119  -0.26367 -0.05489 184 GLU A OE2 
1395 N N   . ARG A 185 ? 0.69241 0.80131 0.41893 0.07655  -0.13642 -0.07877 185 ARG A N   
1396 C CA  . ARG A 185 ? 0.75290 0.84956 0.41256 0.09506  -0.12146 -0.08729 185 ARG A CA  
1397 C C   . ARG A 185 ? 0.75278 0.86119 0.38967 0.10138  -0.08318 -0.06346 185 ARG A C   
1398 O O   . ARG A 185 ? 0.75135 0.84955 0.32420 0.12164  -0.07494 -0.06060 185 ARG A O   
1399 C CB  . ARG A 185 ? 0.72443 0.81707 0.39806 0.09002  -0.11225 -0.10441 185 ARG A CB  
1400 C CG  . ARG A 185 ? 0.82120 0.89349 0.48667 0.09522  -0.14904 -0.13320 185 ARG A CG  
1401 C CD  . ARG A 185 ? 0.78169 0.84839 0.45105 0.09400  -0.13664 -0.14927 185 ARG A CD  
1402 N NE  . ARG A 185 ? 0.68381 0.76504 0.42009 0.07259  -0.12169 -0.14027 185 ARG A NE  
1403 C CZ  . ARG A 185 ? 0.69117 0.78418 0.43727 0.06752  -0.08639 -0.12850 185 ARG A CZ  
1404 N NH1 . ARG A 185 ? 0.64016 0.73451 0.34403 0.08021  -0.05991 -0.12265 185 ARG A NH1 
1405 N NH2 . ARG A 185 ? 0.62065 0.72327 0.42140 0.05057  -0.07761 -0.12196 185 ARG A NH2 
1406 N N   . HIS A 186 ? 0.60419 0.70379 0.57152 -0.01529 -0.15918 -0.08602 186 HIS A N   
1407 C CA  . HIS A 186 ? 0.60955 0.69329 0.54899 -0.01151 -0.15544 -0.07380 186 HIS A CA  
1408 C C   . HIS A 186 ? 0.64249 0.72595 0.57036 -0.00305 -0.16774 -0.05955 186 HIS A C   
1409 O O   . HIS A 186 ? 0.67245 0.74043 0.57556 -0.00039 -0.16463 -0.04890 186 HIS A O   
1410 C CB  . HIS A 186 ? 0.62277 0.69476 0.57450 -0.00781 -0.14083 -0.06885 186 HIS A CB  
1411 C CG  . HIS A 186 ? 0.61527 0.68381 0.57089 -0.01406 -0.12843 -0.07959 186 HIS A CG  
1412 N ND1 . HIS A 186 ? 0.64091 0.70016 0.57398 -0.01825 -0.12023 -0.08166 186 HIS A ND1 
1413 C CD2 . HIS A 186 ? 0.55378 0.62664 0.53453 -0.01644 -0.12248 -0.08889 186 HIS A CD2 
1414 C CE1 . HIS A 186 ? 0.63297 0.69274 0.57878 -0.02175 -0.11069 -0.09194 186 HIS A CE1 
1415 N NE2 . HIS A 186 ? 0.57304 0.63937 0.54686 -0.02037 -0.11181 -0.09569 186 HIS A NE2 
1416 N N   . HIS A 187 ? 0.63086 0.73091 0.57780 0.00137  -0.18103 -0.05939 187 HIS A N   
1417 C CA  . HIS A 187 ? 0.64779 0.75012 0.58859 0.01163  -0.19456 -0.04579 187 HIS A CA  
1418 C C   . HIS A 187 ? 0.60055 0.68540 0.54340 0.02077  -0.18604 -0.03152 187 HIS A C   
1419 O O   . HIS A 187 ? 0.64528 0.71618 0.56382 0.02615  -0.18868 -0.01879 187 HIS A O   
1420 C CB  . HIS A 187 ? 0.68927 0.78969 0.59028 0.00963  -0.20572 -0.04191 187 HIS A CB  
1421 C CG  . HIS A 187 ? 0.74308 0.86406 0.64115 0.00105  -0.21667 -0.05655 187 HIS A CG  
1422 N ND1 . HIS A 187 ? 0.74483 0.86371 0.62534 -0.01165 -0.20917 -0.07021 187 HIS A ND1 
1423 C CD2 . HIS A 187 ? 0.69219 0.83783 0.60397 0.00285  -0.23431 -0.06134 187 HIS A CD2 
1424 C CE1 . HIS A 187 ? 0.74251 0.88240 0.62449 -0.01798 -0.22109 -0.08322 187 HIS A CE1 
1425 N NE2 . HIS A 187 ? 0.76798 0.92540 0.66869 -0.00963 -0.23706 -0.07823 187 HIS A NE2 
1426 N N   . VAL A 188 ? 0.58072 0.66543 0.55218 0.02213  -0.17502 -0.03384 188 VAL A N   
1427 C CA  . VAL A 188 ? 0.59358 0.66411 0.56950 0.02955  -0.16591 -0.02325 188 VAL A CA  
1428 C C   . VAL A 188 ? 0.57112 0.65414 0.58299 0.03739  -0.16877 -0.02162 188 VAL A C   
1429 O O   . VAL A 188 ? 0.54776 0.64909 0.58490 0.03486  -0.17296 -0.03049 188 VAL A O   
1430 C CB  . VAL A 188 ? 0.57710 0.63542 0.55039 0.02422  -0.14842 -0.02670 188 VAL A CB  
1431 C CG1 . VAL A 188 ? 0.63122 0.67660 0.57014 0.01737  -0.14399 -0.02754 188 VAL A CG1 
1432 C CG2 . VAL A 188 ? 0.51397 0.58335 0.51208 0.01905  -0.14285 -0.03786 188 VAL A CG2 
1433 N N   . GLN A 189 ? 0.53933 0.61186 0.55434 0.04626  -0.16503 -0.01122 189 GLN A N   
1434 C CA  . GLN A 189 ? 0.54399 0.62600 0.59310 0.05375  -0.16379 -0.00994 189 GLN A CA  
1435 C C   . GLN A 189 ? 0.52344 0.59579 0.58183 0.05237  -0.14599 -0.01068 189 GLN A C   
1436 O O   . GLN A 189 ? 0.50043 0.57816 0.58438 0.05780  -0.14169 -0.00974 189 GLN A O   
1437 C CB  . GLN A 189 ? 0.56885 0.64824 0.61888 0.06642  -0.17342 0.00158  189 GLN A CB  
1438 C CG  . GLN A 189 ? 0.59594 0.68436 0.63164 0.06984  -0.19306 0.00537  189 GLN A CG  
1439 C CD  . GLN A 189 ? 0.58461 0.70087 0.63961 0.06448  -0.20406 -0.00680 189 GLN A CD  
1440 O OE1 . GLN A 189 ? 0.58696 0.70840 0.62161 0.05714  -0.21191 -0.01203 189 GLN A OE1 
1441 N NE2 . GLN A 189 ? 0.52894 0.66337 0.62381 0.06702  -0.20337 -0.01269 189 GLN A NE2 
1442 N N   . TRP A 190 ? 0.45827 0.51817 0.49657 0.04524  -0.13566 -0.01289 190 TRP A N   
1443 C CA  . TRP A 190 ? 0.49547 0.54795 0.53832 0.04380  -0.12032 -0.01358 190 TRP A CA  
1444 C C   . TRP A 190 ? 0.50223 0.55592 0.54003 0.03521  -0.11390 -0.02107 190 TRP A C   
1445 O O   . TRP A 190 ? 0.49156 0.54278 0.51065 0.02988  -0.11721 -0.02445 190 TRP A O   
1446 C CB  . TRP A 190 ? 0.51364 0.54750 0.53630 0.04613  -0.11330 -0.00705 190 TRP A CB  
1447 C CG  . TRP A 190 ? 0.56445 0.59393 0.59822 0.05583  -0.11444 0.00006  190 TRP A CG  
1448 C CD1 . TRP A 190 ? 0.59771 0.62089 0.62376 0.06300  -0.12436 0.00817  190 TRP A CD1 
1449 C CD2 . TRP A 190 ? 0.52937 0.55984 0.58389 0.05998  -0.10475 -0.00027 190 TRP A CD2 
1450 N NE1 . TRP A 190 ? 0.57418 0.59411 0.61804 0.07229  -0.12149 0.01272  190 TRP A NE1 
1451 C CE2 . TRP A 190 ? 0.60954 0.63433 0.67114 0.06992  -0.10890 0.00662  190 TRP A CE2 
1452 C CE3 . TRP A 190 ? 0.57811 0.61362 0.64495 0.05654  -0.09279 -0.00542 190 TRP A CE3 
1453 C CZ2 . TRP A 190 ? 0.60299 0.62743 0.68571 0.07586  -0.10035 0.00653  190 TRP A CZ2 
1454 C CZ3 . TRP A 190 ? 0.52465 0.56017 0.60888 0.06152  -0.08449 -0.00505 190 TRP A CZ3 
1455 C CH2 . TRP A 190 ? 0.55604 0.58633 0.64919 0.07079  -0.08778 -0.00008 190 TRP A CH2 
1456 N N   . LEU A 191 ? 0.42813 0.48521 0.48253 0.03433  -0.10425 -0.02335 191 LEU A N   
1457 C CA  . LEU A 191 ? 0.45277 0.50996 0.50568 0.02855  -0.09758 -0.02865 191 LEU A CA  
1458 C C   . LEU A 191 ? 0.42744 0.48074 0.48277 0.03003  -0.08547 -0.02591 191 LEU A C   
1459 O O   . LEU A 191 ? 0.41593 0.47235 0.48690 0.03345  -0.08122 -0.02317 191 LEU A O   
1460 C CB  . LEU A 191 ? 0.37755 0.44549 0.45135 0.02520  -0.10047 -0.03492 191 LEU A CB  
1461 C CG  . LEU A 191 ? 0.40776 0.47432 0.48987 0.02164  -0.09099 -0.03824 191 LEU A CG  
1462 C CD1 . LEU A 191 ? 0.40783 0.46817 0.47108 0.01803  -0.08926 -0.04216 191 LEU A CD1 
1463 C CD2 . LEU A 191 ? 0.36040 0.43576 0.46707 0.01795  -0.09254 -0.04435 191 LEU A CD2 
1464 N N   . ILE A 192 ? 0.41613 0.46428 0.45586 0.02737  -0.08001 -0.02728 192 ILE A N   
1465 C CA  . ILE A 192 ? 0.38536 0.43276 0.42469 0.02849  -0.07015 -0.02539 192 ILE A CA  
1466 C C   . ILE A 192 ? 0.42356 0.47340 0.46582 0.02657  -0.06719 -0.02804 192 ILE A C   
1467 O O   . ILE A 192 ? 0.40337 0.45234 0.43743 0.02352  -0.06999 -0.03281 192 ILE A O   
1468 C CB  . ILE A 192 ? 0.42668 0.46795 0.44670 0.02788  -0.06640 -0.02507 192 ILE A CB  
1469 C CG1 . ILE A 192 ? 0.41072 0.44548 0.42832 0.03056  -0.06818 -0.02174 192 ILE A CG1 
1470 C CG2 . ILE A 192 ? 0.42711 0.47162 0.44626 0.02861  -0.05772 -0.02454 192 ILE A CG2 
1471 C CD1 . ILE A 192 ? 0.41131 0.43664 0.40957 0.02826  -0.06372 -0.02242 192 ILE A CD1 
1472 N N   . HIS A 193 ? 0.37081 0.42274 0.42444 0.02860  -0.06077 -0.02470 193 HIS A N   
1473 C CA  . HIS A 193 ? 0.37400 0.42568 0.43118 0.02865  -0.05738 -0.02500 193 HIS A CA  
1474 C C   . HIS A 193 ? 0.40361 0.45593 0.46251 0.03215  -0.04936 -0.01818 193 HIS A C   
1475 O O   . HIS A 193 ? 0.37719 0.43095 0.43618 0.03323  -0.04580 -0.01498 193 HIS A O   
1476 C CB  . HIS A 193 ? 0.36690 0.41805 0.44050 0.02588  -0.05968 -0.02876 193 HIS A CB  
1477 C CG  . HIS A 193 ? 0.41328 0.46578 0.50639 0.02576  -0.05593 -0.02580 193 HIS A CG  
1478 N ND1 . HIS A 193 ? 0.36880 0.41773 0.46982 0.02729  -0.04684 -0.02004 193 HIS A ND1 
1479 C CD2 . HIS A 193 ? 0.38910 0.44694 0.49632 0.02408  -0.05972 -0.02803 193 HIS A CD2 
1480 C CE1 . HIS A 193 ? 0.39953 0.45067 0.51855 0.02528  -0.04358 -0.01950 193 HIS A CE1 
1481 N NE2 . HIS A 193 ? 0.38128 0.43938 0.50624 0.02353  -0.05171 -0.02503 193 HIS A NE2 
1482 N N   . GLY A 194 ? 0.38804 0.43912 0.44733 0.03433  -0.04636 -0.01593 194 GLY A N   
1483 C CA  . GLY A 194 ? 0.37330 0.42423 0.43188 0.03822  -0.03941 -0.00764 194 GLY A CA  
1484 C C   . GLY A 194 ? 0.40730 0.45091 0.48034 0.03902  -0.03501 -0.00355 194 GLY A C   
1485 O O   . GLY A 194 ? 0.38001 0.42043 0.46872 0.03500  -0.03443 -0.00643 194 GLY A O   
1486 N N   . HIS A 195 ? 0.39545 0.43663 0.46393 0.04435  -0.03194 0.00304  195 HIS A N   
1487 C CA  . HIS A 195 ? 0.47177 0.50215 0.55182 0.04669  -0.02647 0.00883  195 HIS A CA  
1488 C C   . HIS A 195 ? 0.48660 0.51010 0.57312 0.04543  -0.01706 0.01757  195 HIS A C   
1489 O O   . HIS A 195 ? 0.44395 0.45951 0.52745 0.05022  -0.01081 0.02856  195 HIS A O   
1490 C CB  . HIS A 195 ? 0.42690 0.45158 0.52259 0.04236  -0.02855 -0.00050 195 HIS A CB  
1491 C CG  . HIS A 195 ? 0.44004 0.45079 0.54959 0.04402  -0.02120 0.00421  195 HIS A CG  
1492 N ND1 . HIS A 195 ? 0.45855 0.46341 0.56560 0.05210  -0.01955 0.01034  195 HIS A ND1 
1493 C CD2 . HIS A 195 ? 0.42601 0.42687 0.55327 0.03881  -0.01426 0.00389  195 HIS A CD2 
1494 C CE1 . HIS A 195 ? 0.53722 0.52613 0.65875 0.05229  -0.01141 0.01461  195 HIS A CE1 
1495 N NE2 . HIS A 195 ? 0.49106 0.47715 0.62498 0.04332  -0.00749 0.01016  195 HIS A NE2 
1496 N N   . THR A 196 ? 0.38544 0.41182 0.48125 0.03935  -0.01553 0.01328  196 THR A N   
1497 C CA  . THR A 196 ? 0.44319 0.46325 0.55066 0.03622  -0.00494 0.01899  196 THR A CA  
1498 C C   . THR A 196 ? 0.48292 0.50532 0.57586 0.03851  0.00229  0.02836  196 THR A C   
1499 O O   . THR A 196 ? 0.48171 0.49806 0.58167 0.03563  0.01323  0.03418  196 THR A O   
1500 C CB  . THR A 196 ? 0.47113 0.49660 0.59868 0.02901  -0.00625 0.00932  196 THR A CB  
1501 O OG1 . THR A 196 ? 0.43140 0.46835 0.55196 0.02943  -0.01197 0.00515  196 THR A OG1 
1502 C CG2 . THR A 196 ? 0.44350 0.46770 0.58378 0.02550  -0.01317 -0.00081 196 THR A CG2 
1503 N N   . HIS A 197 ? 0.43090 0.46230 0.50392 0.04241  -0.00251 0.02876  197 HIS A N   
1504 C CA  . HIS A 197 ? 0.44783 0.48346 0.50401 0.04395  0.00388  0.03564  197 HIS A CA  
1505 C C   . HIS A 197 ? 0.45739 0.49557 0.52346 0.03827  0.01209  0.03268  197 HIS A C   
1506 O O   . HIS A 197 ? 0.44946 0.48676 0.50726 0.03750  0.02239  0.03939  197 HIS A O   
1507 C CB  . HIS A 197 ? 0.43719 0.46419 0.48229 0.04882  0.01039  0.04997  197 HIS A CB  
1508 C CG  . HIS A 197 ? 0.52363 0.55140 0.55861 0.05675  0.00221  0.05375  197 HIS A CG  
1509 N ND1 . HIS A 197 ? 0.61438 0.63817 0.63457 0.06420  0.00450  0.06767  197 HIS A ND1 
1510 C CD2 . HIS A 197 ? 0.50278 0.53566 0.54121 0.05879  -0.00798 0.04545  197 HIS A CD2 
1511 C CE1 . HIS A 197 ? 0.56733 0.59534 0.58510 0.07138  -0.00471 0.06727  197 HIS A CE1 
1512 N NE2 . HIS A 197 ? 0.54005 0.57361 0.56903 0.06755  -0.01152 0.05318  197 HIS A NE2 
1513 N N   . ARG A 198 ? 0.41995 0.46226 0.50366 0.03461  0.00772  0.02262  198 ARG A N   
1514 C CA  . ARG A 198 ? 0.44381 0.49070 0.54305 0.03041  0.01445  0.01853  198 ARG A CA  
1515 C C   . ARG A 198 ? 0.40160 0.45708 0.50043 0.03135  0.00702  0.00980  198 ARG A C   
1516 O O   . ARG A 198 ? 0.41547 0.47432 0.53153 0.03027  0.00026  0.00304  198 ARG A O   
1517 C CB  . ARG A 198 ? 0.42644 0.47070 0.55340 0.02562  0.01655  0.01528  198 ARG A CB  
1518 C CG  . ARG A 198 ? 0.51626 0.54848 0.64676 0.02324  0.02789  0.02402  198 ARG A CG  
1519 C CD  . ARG A 198 ? 0.52803 0.55893 0.68848 0.01677  0.02948  0.01733  198 ARG A CD  
1520 N NE  . ARG A 198 ? 0.52800 0.54516 0.69536 0.01268  0.04342  0.02483  198 ARG A NE  
1521 C CZ  . ARG A 198 ? 0.65514 0.65699 0.81703 0.01456  0.04490  0.03156  198 ARG A CZ  
1522 N NH1 . ARG A 198 ? 0.61969 0.62009 0.76992 0.02053  0.03328  0.03090  198 ARG A NH1 
1523 N NH2 . ARG A 198 ? 0.75685 0.74360 0.92630 0.01033  0.05947  0.03899  198 ARG A NH2 
1524 N N   . PRO A 199 ? 0.42683 0.48566 0.50584 0.03335  0.00801  0.00974  199 PRO A N   
1525 C CA  . PRO A 199 ? 0.39050 0.45347 0.46817 0.03420  0.00213  0.00192  199 PRO A CA  
1526 C C   . PRO A 199 ? 0.41447 0.48098 0.51480 0.03331  0.00548  -0.00287 199 PRO A C   
1527 O O   . PRO A 199 ? 0.42204 0.49102 0.53014 0.03151  0.01694  -0.00209 199 PRO A O   
1528 C CB  . PRO A 199 ? 0.39609 0.46207 0.45033 0.03473  0.00655  0.00193  199 PRO A CB  
1529 C CG  . PRO A 199 ? 0.40603 0.47183 0.45201 0.03414  0.01642  0.00991  199 PRO A CG  
1530 C CD  . PRO A 199 ? 0.41759 0.47667 0.47424 0.03459  0.01484  0.01653  199 PRO A CD  
1531 N N   . ALA A 200 ? 0.37579 0.44331 0.48704 0.03485  -0.00463 -0.00767 200 ALA A N   
1532 C CA  . ALA A 200 ? 0.41764 0.49101 0.55511 0.03566  -0.00487 -0.01175 200 ALA A CA  
1533 C C   . ALA A 200 ? 0.44200 0.51528 0.58204 0.03899  -0.01862 -0.01492 200 ALA A C   
1534 O O   . ALA A 200 ? 0.38486 0.45302 0.50799 0.03890  -0.02683 -0.01429 200 ALA A O   
1535 C CB  . ALA A 200 ? 0.41506 0.49247 0.57501 0.03201  -0.00159 -0.01132 200 ALA A CB  
1536 N N   . VAL A 201 ? 0.41168 0.49115 0.57326 0.04224  -0.02070 -0.01805 201 VAL A N   
1537 C CA  . VAL A 201 ? 0.40003 0.48109 0.56771 0.04647  -0.03475 -0.01939 201 VAL A CA  
1538 C C   . VAL A 201 ? 0.40152 0.49626 0.60037 0.04634  -0.03934 -0.02268 201 VAL A C   
1539 O O   . VAL A 201 ? 0.40121 0.50456 0.62345 0.04714  -0.03130 -0.02525 201 VAL A O   
1540 C CB  . VAL A 201 ? 0.41009 0.48603 0.57517 0.05269  -0.03462 -0.01953 201 VAL A CB  
1541 C CG1 . VAL A 201 ? 0.40900 0.48566 0.57927 0.05831  -0.04983 -0.01832 201 VAL A CG1 
1542 C CG2 . VAL A 201 ? 0.43347 0.49720 0.56914 0.05086  -0.02952 -0.01858 201 VAL A CG2 
1543 N N   . HIS A 202 ? 0.40502 0.50329 0.60506 0.04460  -0.05167 -0.02410 202 HIS A N   
1544 C CA  . HIS A 202 ? 0.41344 0.52730 0.64275 0.04310  -0.05796 -0.02934 202 HIS A CA  
1545 C C   . HIS A 202 ? 0.42064 0.54129 0.65259 0.04912  -0.07544 -0.02998 202 HIS A C   
1546 O O   . HIS A 202 ? 0.43601 0.54722 0.64246 0.05030  -0.08403 -0.02692 202 HIS A O   
1547 C CB  . HIS A 202 ? 0.40527 0.51917 0.63546 0.03472  -0.05755 -0.03231 202 HIS A CB  
1548 C CG  . HIS A 202 ? 0.40397 0.50803 0.62680 0.02993  -0.04181 -0.02890 202 HIS A CG  
1549 N ND1 . HIS A 202 ? 0.42734 0.53593 0.67109 0.02589  -0.02870 -0.02995 202 HIS A ND1 
1550 C CD2 . HIS A 202 ? 0.41909 0.50960 0.61567 0.02891  -0.03733 -0.02386 202 HIS A CD2 
1551 C CE1 . HIS A 202 ? 0.45153 0.54785 0.67927 0.02296  -0.01704 -0.02418 202 HIS A CE1 
1552 N NE2 . HIS A 202 ? 0.47327 0.55968 0.67338 0.02539  -0.02289 -0.02051 202 HIS A NE2 
1553 N N   . GLU A 203 ? 0.41894 0.55676 0.68164 0.05300  -0.08061 -0.03376 203 GLU A N   
1554 C CA  . GLU A 203 ? 0.41983 0.56833 0.68812 0.05922  -0.09941 -0.03407 203 GLU A CA  
1555 C C   . GLU A 203 ? 0.45345 0.61984 0.73957 0.05234  -0.10834 -0.04255 203 GLU A C   
1556 O O   . GLU A 203 ? 0.43571 0.61289 0.74808 0.04584  -0.09954 -0.04933 203 GLU A O   
1557 C CB  . GLU A 203 ? 0.40474 0.56328 0.69770 0.07014  -0.10180 -0.03295 203 GLU A CB  
1558 C CG  . GLU A 203 ? 0.49910 0.66949 0.79727 0.07866  -0.12293 -0.03120 203 GLU A CG  
1559 C CD  . GLU A 203 ? 0.60873 0.78657 0.93098 0.09212  -0.12562 -0.02838 203 GLU A CD  
1560 O OE1 . GLU A 203 ? 0.68996 0.86693 1.02994 0.09326  -0.10983 -0.03062 203 GLU A OE1 
1561 O OE2 . GLU A 203 ? 0.63673 0.82198 0.96070 0.10188  -0.14354 -0.02405 203 GLU A OE2 
1562 N N   . LEU A 204 ? 0.44003 0.60896 0.71080 0.05276  -0.12479 -0.04279 204 LEU A N   
1563 C CA  . LEU A 204 ? 0.41039 0.59741 0.69510 0.04575  -0.13527 -0.05266 204 LEU A CA  
1564 C C   . LEU A 204 ? 0.45128 0.64832 0.72630 0.05276  -0.15707 -0.05065 204 LEU A C   
1565 O O   . LEU A 204 ? 0.44319 0.63283 0.70625 0.06381  -0.16257 -0.04077 204 LEU A O   
1566 C CB  . LEU A 204 ? 0.38906 0.56373 0.65597 0.03429  -0.12813 -0.05676 204 LEU A CB  
1567 C CG  . LEU A 204 ? 0.42423 0.57951 0.64987 0.03471  -0.13127 -0.05086 204 LEU A CG  
1568 C CD1 . LEU A 204 ? 0.42543 0.58226 0.64148 0.02512  -0.13626 -0.05969 204 LEU A CD1 
1569 C CD2 . LEU A 204 ? 0.43682 0.57086 0.64502 0.03506  -0.11507 -0.04369 204 LEU A CD2 
1570 N N   . GLN A 205 ? 0.46795 0.68119 0.74721 0.04619  -0.16923 -0.05997 205 GLN A N   
1571 C CA  . GLN A 205 ? 0.46111 0.68405 0.72446 0.05130  -0.19076 -0.05811 205 GLN A CA  
1572 C C   . GLN A 205 ? 0.46641 0.68156 0.70008 0.04074  -0.19356 -0.06356 205 GLN A C   
1573 O O   . GLN A 205 ? 0.43869 0.65835 0.68386 0.02887  -0.18682 -0.07554 205 GLN A O   
1574 C CB  . GLN A 205 ? 0.54663 0.80407 0.84573 0.05443  -0.20647 -0.06622 205 GLN A CB  
1575 C CG  . GLN A 205 ? 0.55161 0.81826 0.87972 0.06766  -0.20627 -0.06025 205 GLN A CG  
1576 C CD  . GLN A 205 ? 0.72224 1.00300 1.04876 0.08218  -0.22910 -0.05276 205 GLN A CD  
1577 O OE1 . GLN A 205 ? 0.74728 1.04244 1.06156 0.08065  -0.24775 -0.05594 205 GLN A OE1 
1578 N NE2 . GLN A 205 ? 0.73967 1.01554 1.07731 0.09677  -0.22760 -0.04248 205 GLN A NE2 
1579 N N   . ALA A 206 ? 0.46832 0.67016 0.66429 0.04481  -0.20177 -0.05495 206 ALA A N   
1580 C CA  . ALA A 206 ? 0.53972 0.73466 0.70488 0.03547  -0.20469 -0.06017 206 ALA A CA  
1581 C C   . ALA A 206 ? 0.55619 0.75301 0.69221 0.04209  -0.22304 -0.05239 206 ALA A C   
1582 O O   . ALA A 206 ? 0.59394 0.77989 0.71919 0.05379  -0.22580 -0.03805 206 ALA A O   
1583 C CB  . ALA A 206 ? 0.49775 0.66501 0.63926 0.03084  -0.18713 -0.05663 206 ALA A CB  
1584 N N   . ASN A 207 ? 0.57801 0.78758 0.70053 0.03439  -0.23486 -0.06189 207 ASN A N   
1585 C CA  . ASN A 207 ? 0.58075 0.79405 0.67190 0.03955  -0.25345 -0.05475 207 ASN A CA  
1586 C C   . ASN A 207 ? 0.58258 0.81377 0.69226 0.05445  -0.27035 -0.04566 207 ASN A C   
1587 O O   . ASN A 207 ? 0.60686 0.82979 0.69050 0.06500  -0.28129 -0.03076 207 ASN A O   
1588 C CB  . ASN A 207 ? 0.58425 0.76627 0.63136 0.04121  -0.24601 -0.04173 207 ASN A CB  
1589 C CG  . ASN A 207 ? 0.60718 0.77138 0.64311 0.02930  -0.22699 -0.04940 207 ASN A CG  
1590 O OD1 . ASN A 207 ? 0.60876 0.78002 0.63996 0.01769  -0.22660 -0.06341 207 ASN A OD1 
1591 N ND2 . ASN A 207 ? 0.56901 0.71093 0.60181 0.03238  -0.21120 -0.04103 207 ASN A ND2 
1592 N N   . GLY A 208 ? 0.53104 0.78589 0.68683 0.05577  -0.27158 -0.05415 208 GLY A N   
1593 C CA  . GLY A 208 ? 0.57203 0.84871 0.75275 0.07025  -0.28776 -0.04799 208 GLY A CA  
1594 C C   . GLY A 208 ? 0.66172 0.91948 0.84611 0.08567  -0.28122 -0.03076 208 GLY A C   
1595 O O   . GLY A 208 ? 0.63626 0.90690 0.83331 0.10069  -0.29618 -0.02198 208 GLY A O   
1596 N N   . GLN A 209 ? 0.62257 0.85114 0.79752 0.08278  -0.25959 -0.02633 209 GLN A N   
1597 C CA  . GLN A 209 ? 0.60106 0.80938 0.77759 0.09531  -0.25083 -0.01222 209 GLN A CA  
1598 C C   . GLN A 209 ? 0.60615 0.80326 0.80097 0.08889  -0.22705 -0.01766 209 GLN A C   
1599 O O   . GLN A 209 ? 0.53984 0.73550 0.73297 0.07529  -0.21668 -0.02797 209 GLN A O   
1600 C CB  . GLN A 209 ? 0.67837 0.85563 0.80718 0.09918  -0.25050 0.00289  209 GLN A CB  
1601 C CG  . GLN A 209 ? 0.79647 0.97941 0.90078 0.10781  -0.27326 0.01300  209 GLN A CG  
1602 C CD  . GLN A 209 ? 0.91710 1.10945 1.04405 0.12746  -0.28625 0.02457  209 GLN A CD  
1603 O OE1 . GLN A 209 ? 1.04666 1.21551 1.15224 0.13906  -0.28745 0.04166  209 GLN A OE1 
1604 N NE2 . GLN A 209 ? 0.90491 1.13181 1.07644 0.13133  -0.29588 0.01497  209 GLN A NE2 
1605 N N   . PRO A 210 ? 0.54554 0.73457 0.75787 0.09879  -0.21792 -0.01092 210 PRO A N   
1606 C CA  . PRO A 210 ? 0.54033 0.71678 0.76304 0.09277  -0.19498 -0.01470 210 PRO A CA  
1607 C C   . PRO A 210 ? 0.49874 0.64857 0.68312 0.08361  -0.18321 -0.01247 210 PRO A C   
1608 O O   . PRO A 210 ? 0.54750 0.67986 0.69776 0.08592  -0.18772 -0.00382 210 PRO A O   
1609 C CB  . PRO A 210 ? 0.57791 0.74689 0.81661 0.10636  -0.18935 -0.00646 210 PRO A CB  
1610 C CG  . PRO A 210 ? 0.56082 0.74589 0.81183 0.12039  -0.21011 -0.00051 210 PRO A CG  
1611 C CD  . PRO A 210 ? 0.66265 0.85909 0.89253 0.11610  -0.22911 -0.00166 210 PRO A CD  
1612 N N   . ALA A 211 ? 0.45742 0.60483 0.64823 0.07321  -0.16794 -0.02023 211 ALA A N   
1613 C CA  . ALA A 211 ? 0.48315 0.60937 0.64359 0.06506  -0.15642 -0.01949 211 ALA A CA  
1614 C C   . ALA A 211 ? 0.48300 0.60262 0.65572 0.06199  -0.13727 -0.02136 211 ALA A C   
1615 O O   . ALA A 211 ? 0.43729 0.56993 0.64156 0.06290  -0.13217 -0.02541 211 ALA A O   
1616 C CB  . ALA A 211 ? 0.49784 0.62917 0.64635 0.05406  -0.16089 -0.02790 211 ALA A CB  
1617 N N   . TRP A 212 ? 0.42403 0.52463 0.57114 0.05793  -0.12653 -0.01876 212 TRP A N   
1618 C CA  . TRP A 212 ? 0.41495 0.50888 0.56730 0.05559  -0.10943 -0.01927 212 TRP A CA  
1619 C C   . TRP A 212 ? 0.43376 0.51963 0.56819 0.04696  -0.10205 -0.02195 212 TRP A C   
1620 O O   . TRP A 212 ? 0.41930 0.49663 0.52863 0.04425  -0.10607 -0.02137 212 TRP A O   
1621 C CB  . TRP A 212 ? 0.46980 0.54969 0.61270 0.06198  -0.10231 -0.01306 212 TRP A CB  
1622 C CG  . TRP A 212 ? 0.49103 0.57806 0.65696 0.07207  -0.10693 -0.01054 212 TRP A CG  
1623 C CD1 . TRP A 212 ? 0.49927 0.59508 0.69377 0.07531  -0.09827 -0.01326 212 TRP A CD1 
1624 C CD2 . TRP A 212 ? 0.51271 0.59922 0.67566 0.08092  -0.12128 -0.00458 212 TRP A CD2 
1625 N NE1 . TRP A 212 ? 0.53802 0.63990 0.75090 0.08632  -0.10643 -0.01030 212 TRP A NE1 
1626 C CE2 . TRP A 212 ? 0.51426 0.61012 0.70762 0.09061  -0.12136 -0.00397 212 TRP A CE2 
1627 C CE3 . TRP A 212 ? 0.55368 0.63247 0.69025 0.08185  -0.13372 0.00081  212 TRP A CE3 
1628 C CZ2 . TRP A 212 ? 0.58056 0.67831 0.78006 0.10274  -0.13476 0.00280  212 TRP A CZ2 
1629 C CZ3 . TRP A 212 ? 0.58383 0.66332 0.72279 0.09305  -0.14683 0.00847  212 TRP A CZ3 
1630 C CH2 . TRP A 212 ? 0.57138 0.66027 0.74224 0.10414  -0.14791 0.00989  212 TRP A CH2 
1631 N N   . ARG A 213 ? 0.41675 0.50529 0.56472 0.04307  -0.09067 -0.02452 213 ARG A N   
1632 C CA  . ARG A 213 ? 0.42633 0.50736 0.56130 0.03714  -0.08258 -0.02552 213 ARG A CA  
1633 C C   . ARG A 213 ? 0.46690 0.54099 0.59642 0.03858  -0.06924 -0.02153 213 ARG A C   
1634 O O   . ARG A 213 ? 0.41747 0.49652 0.56490 0.03941  -0.06121 -0.02119 213 ARG A O   
1635 C CB  . ARG A 213 ? 0.40075 0.48927 0.55469 0.03125  -0.08072 -0.03096 213 ARG A CB  
1636 C CG  . ARG A 213 ? 0.40785 0.48711 0.55091 0.02703  -0.07222 -0.03065 213 ARG A CG  
1637 C CD  . ARG A 213 ? 0.38903 0.47209 0.55031 0.02085  -0.07088 -0.03671 213 ARG A CD  
1638 N NE  . ARG A 213 ? 0.40014 0.49029 0.58841 0.01922  -0.06374 -0.03740 213 ARG A NE  
1639 C CZ  . ARG A 213 ? 0.46888 0.55248 0.66193 0.01793  -0.04988 -0.03286 213 ARG A CZ  
1640 N NH1 . ARG A 213 ? 0.39164 0.46302 0.56489 0.01949  -0.04336 -0.02667 213 ARG A NH1 
1641 N NH2 . ARG A 213 ? 0.40155 0.49190 0.61976 0.01498  -0.04237 -0.03449 213 ARG A NH2 
1642 N N   . VAL A 214 ? 0.39436 0.45858 0.49931 0.03814  -0.06656 -0.01957 214 VAL A N   
1643 C CA  . VAL A 214 ? 0.38775 0.44729 0.48371 0.03892  -0.05550 -0.01719 214 VAL A CA  
1644 C C   . VAL A 214 ? 0.38095 0.43916 0.46775 0.03566  -0.05024 -0.01660 214 VAL A C   
1645 O O   . VAL A 214 ? 0.38578 0.44149 0.46113 0.03362  -0.05491 -0.01832 214 VAL A O   
1646 C CB  . VAL A 214 ? 0.43287 0.48379 0.50992 0.04067  -0.05602 -0.01654 214 VAL A CB  
1647 C CG1 . VAL A 214 ? 0.42335 0.47210 0.49239 0.04024  -0.04450 -0.01663 214 VAL A CG1 
1648 C CG2 . VAL A 214 ? 0.42339 0.47297 0.50948 0.04582  -0.06213 -0.01513 214 VAL A CG2 
1649 N N   . VAL A 215 ? 0.35814 0.41799 0.44970 0.03563  -0.04027 -0.01389 215 VAL A N   
1650 C CA  . VAL A 215 ? 0.35479 0.41313 0.44037 0.03436  -0.03549 -0.01088 215 VAL A CA  
1651 C C   . VAL A 215 ? 0.41307 0.47140 0.48072 0.03560  -0.02894 -0.00838 215 VAL A C   
1652 O O   . VAL A 215 ? 0.36580 0.42591 0.43390 0.03604  -0.02212 -0.00813 215 VAL A O   
1653 C CB  . VAL A 215 ? 0.38130 0.44065 0.48591 0.03269  -0.02907 -0.00837 215 VAL A CB  
1654 C CG1 . VAL A 215 ? 0.37055 0.42459 0.46813 0.03273  -0.02470 -0.00334 215 VAL A CG1 
1655 C CG2 . VAL A 215 ? 0.39282 0.45593 0.51808 0.03030  -0.03589 -0.01350 215 VAL A CG2 
1656 N N   . LEU A 216 ? 0.40146 0.45952 0.45459 0.03603  -0.03096 -0.00773 216 LEU A N   
1657 C CA  . LEU A 216 ? 0.38977 0.45170 0.42576 0.03708  -0.02688 -0.00642 216 LEU A CA  
1658 C C   . LEU A 216 ? 0.43718 0.50022 0.47248 0.03894  -0.01953 0.00129  216 LEU A C   
1659 O O   . LEU A 216 ? 0.37504 0.43344 0.42203 0.03938  -0.01763 0.00602  216 LEU A O   
1660 C CB  . LEU A 216 ? 0.36901 0.43338 0.39304 0.03736  -0.03269 -0.00935 216 LEU A CB  
1661 C CG  . LEU A 216 ? 0.39674 0.45946 0.41387 0.03434  -0.03720 -0.01655 216 LEU A CG  
1662 C CD1 . LEU A 216 ? 0.42452 0.48860 0.43688 0.03353  -0.04260 -0.02018 216 LEU A CD1 
1663 C CD2 . LEU A 216 ? 0.40452 0.47048 0.40945 0.03262  -0.03261 -0.02007 216 LEU A CD2 
1664 N N   . GLY A 217 ? 0.43490 0.50360 0.45508 0.03944  -0.01486 0.00238  217 GLY A N   
1665 C CA  . GLY A 217 ? 0.43314 0.50328 0.44574 0.04161  -0.00844 0.01109  217 GLY A CA  
1666 C C   . GLY A 217 ? 0.46052 0.53578 0.45969 0.04610  -0.01372 0.01516  217 GLY A C   
1667 O O   . GLY A 217 ? 0.42878 0.51057 0.42184 0.04620  -0.02049 0.00866  217 GLY A O   
1668 N N   . ALA A 218 ? 0.42712 0.49913 0.42290 0.05010  -0.01015 0.02631  218 ALA A N   
1669 C CA  . ALA A 218 ? 0.47346 0.55203 0.45613 0.05660  -0.01524 0.03225  218 ALA A CA  
1670 C C   . ALA A 218 ? 0.46633 0.55899 0.42723 0.05649  -0.01426 0.03152  218 ALA A C   
1671 O O   . ALA A 218 ? 0.45745 0.55058 0.41236 0.05199  -0.00623 0.03023  218 ALA A O   
1672 C CB  . ALA A 218 ? 0.48090 0.54810 0.46675 0.06211  -0.01152 0.04642  218 ALA A CB  
1673 N N   . TRP A 219 ? 0.39615 0.50211 0.34637 0.06119  -0.02234 0.03094  219 TRP A N   
1674 C CA  . TRP A 219 ? 0.44395 0.56742 0.37319 0.06061  -0.02334 0.02814  219 TRP A CA  
1675 C C   . TRP A 219 ? 0.49783 0.62221 0.41103 0.06726  -0.02125 0.04397  219 TRP A C   
1676 O O   . TRP A 219 ? 0.51485 0.64981 0.41913 0.07551  -0.02924 0.05069  219 TRP A O   
1677 C CB  . TRP A 219 ? 0.41524 0.55602 0.34269 0.06163  -0.03337 0.01822  219 TRP A CB  
1678 C CG  . TRP A 219 ? 0.39226 0.53119 0.32986 0.05367  -0.03349 0.00306  219 TRP A CG  
1679 C CD1 . TRP A 219 ? 0.41128 0.53403 0.36456 0.05052  -0.03134 0.00074  219 TRP A CD1 
1680 C CD2 . TRP A 219 ? 0.39184 0.54508 0.32331 0.04769  -0.03563 -0.01127 219 TRP A CD2 
1681 N NE1 . TRP A 219 ? 0.38433 0.50875 0.33930 0.04391  -0.03216 -0.01216 219 TRP A NE1 
1682 C CE2 . TRP A 219 ? 0.41955 0.56126 0.36213 0.04152  -0.03375 -0.01998 219 TRP A CE2 
1683 C CE3 . TRP A 219 ? 0.43097 0.60616 0.34850 0.04644  -0.03888 -0.01802 219 TRP A CE3 
1684 C CZ2 . TRP A 219 ? 0.39860 0.54645 0.33851 0.03401  -0.03329 -0.03402 219 TRP A CZ2 
1685 C CZ3 . TRP A 219 ? 0.42873 0.61241 0.34613 0.03793  -0.03851 -0.03436 219 TRP A CZ3 
1686 C CH2 . TRP A 219 ? 0.37719 0.54549 0.30559 0.03173  -0.03490 -0.04164 219 TRP A CH2 
1687 N N   . HIS A 220 ? 0.56235 0.67568 0.47177 0.06387  -0.01000 0.05039  220 HIS A N   
1688 C CA  . HIS A 220 ? 0.62924 0.73868 0.52138 0.06912  -0.00535 0.06751  220 HIS A CA  
1689 C C   . HIS A 220 ? 0.66019 0.78692 0.52426 0.06667  -0.00370 0.06554  220 HIS A C   
1690 O O   . HIS A 220 ? 0.76673 0.90799 0.61194 0.07353  -0.01205 0.07185  220 HIS A O   
1691 C CB  . HIS A 220 ? 0.66116 0.74911 0.56467 0.06567  0.00771  0.07552  220 HIS A CB  
1692 C CG  . HIS A 220 ? 0.82799 0.90730 0.71333 0.06994  0.01505  0.09441  220 HIS A CG  
1693 N ND1 . HIS A 220 ? 0.79093 0.86791 0.66177 0.06376  0.02845  0.09773  220 HIS A ND1 
1694 C CD2 . HIS A 220 ? 0.80976 0.88092 0.68821 0.08002  0.01169  0.11165  220 HIS A CD2 
1695 C CE1 . HIS A 220 ? 0.81117 0.87828 0.66459 0.06907  0.03328  0.11695  220 HIS A CE1 
1696 N NE2 . HIS A 220 ? 0.80515 0.86776 0.66300 0.07961  0.02291  0.12641  220 HIS A NE2 
1697 N N   . SER A 221 ? 0.67294 0.79947 0.53465 0.05718  0.00690  0.05614  221 SER A N   
1698 C CA  . SER A 221 ? 0.65983 0.80293 0.49587 0.05266  0.01017  0.05019  221 SER A CA  
1699 C C   . SER A 221 ? 0.64435 0.79926 0.48537 0.04478  0.00896  0.02865  221 SER A C   
1700 O O   . SER A 221 ? 0.63162 0.80446 0.45236 0.04106  0.00838  0.02018  221 SER A O   
1701 C CB  . SER A 221 ? 0.72853 0.86195 0.55471 0.04733  0.02674  0.05595  221 SER A CB  
1702 O OG  . SER A 221 ? 0.93537 1.05003 0.76673 0.05196  0.03181  0.07402  221 SER A OG  
1703 N N   . GLU A 222 ? 0.55725 0.70198 0.42373 0.04191  0.00887  0.01974  222 GLU A N   
1704 C CA  . GLU A 222 ? 0.53746 0.68840 0.41037 0.03525  0.00792  0.00123  222 GLU A CA  
1705 C C   . GLU A 222 ? 0.48275 0.62642 0.37688 0.03753  -0.00061 -0.00124 222 GLU A C   
1706 O O   . GLU A 222 ? 0.47675 0.60947 0.38308 0.04297  -0.00366 0.00930  222 GLU A O   
1707 C CB  . GLU A 222 ? 0.53159 0.67410 0.41135 0.02773  0.02165  -0.00790 222 GLU A CB  
1708 C CG  . GLU A 222 ? 0.61594 0.76849 0.47283 0.02292  0.03157  -0.01121 222 GLU A CG  
1709 C CD  . GLU A 222 ? 0.66446 0.81482 0.52771 0.01457  0.04310  -0.02816 222 GLU A CD  
1710 O OE1 . GLU A 222 ? 0.65999 0.79801 0.54698 0.01390  0.04419  -0.03394 222 GLU A OE1 
1711 O OE2 . GLU A 222 ? 0.69741 0.85823 0.54139 0.00903  0.05121  -0.03567 222 GLU A OE2 
1712 N N   . GLY A 223 ? 0.44383 0.59290 0.34148 0.03246  -0.00332 -0.01591 223 GLY A N   
1713 C CA  . GLY A 223 ? 0.43167 0.57308 0.34638 0.03298  -0.00961 -0.01932 223 GLY A CA  
1714 C C   . GLY A 223 ? 0.45041 0.57329 0.38278 0.03044  -0.00391 -0.02098 223 GLY A C   
1715 O O   . GLY A 223 ? 0.42687 0.54436 0.36101 0.02748  0.00556  -0.02304 223 GLY A O   
1716 N N   . SER A 224 ? 0.38838 0.50291 0.33430 0.03196  -0.01010 -0.02052 224 SER A N   
1717 C CA  . SER A 224 ? 0.40692 0.50609 0.36967 0.03099  -0.00809 -0.02087 224 SER A CA  
1718 C C   . SER A 224 ? 0.41922 0.51421 0.38640 0.02928  -0.01477 -0.02676 224 SER A C   
1719 O O   . SER A 224 ? 0.40485 0.50569 0.36974 0.03098  -0.02155 -0.02624 224 SER A O   
1720 C CB  . SER A 224 ? 0.41931 0.51068 0.39459 0.03525  -0.00798 -0.00980 224 SER A CB  
1721 O OG  . SER A 224 ? 0.52866 0.60936 0.52136 0.03447  -0.00832 -0.01123 224 SER A OG  
1722 N N   . MET A 225 ? 0.38697 0.47152 0.36032 0.02628  -0.01226 -0.03202 225 MET A N   
1723 C CA  . MET A 225 ? 0.36113 0.43832 0.33654 0.02436  -0.01753 -0.03567 225 MET A CA  
1724 C C   . MET A 225 ? 0.40272 0.46578 0.38975 0.02536  -0.01685 -0.03405 225 MET A C   
1725 O O   . MET A 225 ? 0.42233 0.48241 0.41627 0.02646  -0.01070 -0.03372 225 MET A O   
1726 C CB  . MET A 225 ? 0.39578 0.47663 0.35953 0.01826  -0.01543 -0.04616 225 MET A CB  
1727 C CG  . MET A 225 ? 0.41452 0.48850 0.37644 0.01430  -0.00642 -0.05299 225 MET A CG  
1728 S SD  . MET A 225 ? 0.49061 0.56716 0.44065 0.00490  -0.00206 -0.06720 225 MET A SD  
1729 C CE  . MET A 225 ? 0.57425 0.65676 0.51908 0.00114  0.00884  -0.07585 225 MET A CE  
1730 N N   . VAL A 226 ? 0.38982 0.44533 0.37891 0.02522  -0.02330 -0.03336 226 VAL A N   
1731 C CA  . VAL A 226 ? 0.39422 0.43695 0.39039 0.02652  -0.02472 -0.03201 226 VAL A CA  
1732 C C   . VAL A 226 ? 0.46456 0.49800 0.44843 0.02198  -0.02307 -0.03728 226 VAL A C   
1733 O O   . VAL A 226 ? 0.39873 0.43432 0.37262 0.01804  -0.02565 -0.04032 226 VAL A O   
1734 C CB  . VAL A 226 ? 0.39454 0.43530 0.40021 0.02939  -0.03354 -0.02676 226 VAL A CB  
1735 C CG1 . VAL A 226 ? 0.38967 0.41875 0.39725 0.03092  -0.03758 -0.02521 226 VAL A CG1 
1736 C CG2 . VAL A 226 ? 0.36226 0.40907 0.38401 0.03284  -0.03270 -0.02233 226 VAL A CG2 
1737 N N   . LYS A 227 ? 0.41616 0.43861 0.40186 0.02231  -0.01743 -0.03879 227 LYS A N   
1738 C CA  . LYS A 227 ? 0.41460 0.42331 0.38942 0.01783  -0.01369 -0.04280 227 LYS A CA  
1739 C C   . LYS A 227 ? 0.47359 0.46630 0.45284 0.02295  -0.01860 -0.03533 227 LYS A C   
1740 O O   . LYS A 227 ? 0.48397 0.47327 0.47736 0.02941  -0.01811 -0.03175 227 LYS A O   
1741 C CB  . LYS A 227 ? 0.44285 0.44929 0.41556 0.01404  -0.00205 -0.05114 227 LYS A CB  
1742 C CG  . LYS A 227 ? 0.52432 0.51336 0.48749 0.00835  0.00459  -0.05612 227 LYS A CG  
1743 C CD  . LYS A 227 ? 0.58364 0.57932 0.54025 -0.00016 0.01507  -0.06929 227 LYS A CD  
1744 C CE  . LYS A 227 ? 0.66454 0.64308 0.62513 -0.00119 0.02669  -0.07442 227 LYS A CE  
1745 N NZ  . LYS A 227 ? 0.69666 0.68066 0.64926 -0.01209 0.03724  -0.08982 227 LYS A NZ  
1746 N N   . VAL A 228 ? 0.47252 0.45708 0.43994 0.02047  -0.02365 -0.03290 228 VAL A N   
1747 C CA  . VAL A 228 ? 0.47057 0.43999 0.43693 0.02537  -0.02972 -0.02460 228 VAL A CA  
1748 C C   . VAL A 228 ? 0.53473 0.48283 0.48759 0.02154  -0.02170 -0.02534 228 VAL A C   
1749 O O   . VAL A 228 ? 0.46519 0.41069 0.40316 0.01252  -0.01646 -0.03109 228 VAL A O   
1750 C CB  . VAL A 228 ? 0.46015 0.43395 0.41979 0.02488  -0.04065 -0.02075 228 VAL A CB  
1751 C CG1 . VAL A 228 ? 0.45150 0.41095 0.40616 0.03004  -0.04817 -0.01160 228 VAL A CG1 
1752 C CG2 . VAL A 228 ? 0.42084 0.41319 0.39589 0.02794  -0.04687 -0.02079 228 VAL A CG2 
1753 N N   . THR A 229 ? 0.42638 0.42492 0.51518 0.00789  0.02211  0.01100  229 THR A N   
1754 C CA  . THR A 229 ? 0.46439 0.43747 0.53764 0.00610  0.02417  0.00918  229 THR A CA  
1755 C C   . THR A 229 ? 0.49628 0.45902 0.55678 0.01187  0.02845  0.01285  229 THR A C   
1756 O O   . THR A 229 ? 0.46673 0.44501 0.53218 0.01810  0.02881  0.01548  229 THR A O   
1757 C CB  . THR A 229 ? 0.49731 0.45852 0.55614 0.01215  0.02031  0.00589  229 THR A CB  
1758 O OG1 . THR A 229 ? 0.50046 0.46203 0.54663 0.02506  0.01952  0.00758  229 THR A OG1 
1759 C CG2 . THR A 229 ? 0.51032 0.48484 0.57948 0.01018  0.01497  0.00264  229 THR A CG2 
1760 N N   . PRO A 230 ? 0.50474 0.44062 0.54788 0.01040  0.03194  0.01266  230 PRO A N   
1761 C CA  . PRO A 230 ? 0.59874 0.52144 0.62392 0.01948  0.03457  0.01612  230 PRO A CA  
1762 C C   . PRO A 230 ? 0.59544 0.52250 0.60976 0.03560  0.02984  0.01553  230 PRO A C   
1763 O O   . PRO A 230 ? 0.56014 0.48725 0.56592 0.04551  0.03010  0.01705  230 PRO A O   
1764 C CB  . PRO A 230 ? 0.61351 0.50127 0.61835 0.01446  0.03942  0.01568  230 PRO A CB  
1765 C CG  . PRO A 230 ? 0.66429 0.54922 0.67748 0.00420  0.03856  0.01046  230 PRO A CG  
1766 C CD  . PRO A 230 ? 0.54040 0.45694 0.58090 -0.00101 0.03487  0.00891  230 PRO A CD  
1767 N N   . ASP A 231 ? 0.54617 0.47857 0.56142 0.03880  0.02540  0.01228  231 ASP A N   
1768 C CA  . ASP A 231 ? 0.49743 0.43229 0.50173 0.05333  0.02142  0.00986  231 ASP A CA  
1769 C C   . ASP A 231 ? 0.54195 0.50785 0.56294 0.05730  0.01985  0.00848  231 ASP A C   
1770 O O   . ASP A 231 ? 0.51483 0.48823 0.53074 0.06939  0.01824  0.00558  231 ASP A O   
1771 C CB  . ASP A 231 ? 0.57364 0.49200 0.56536 0.05491  0.01832  0.00631  231 ASP A CB  
1772 C CG  . ASP A 231 ? 0.67729 0.56089 0.64791 0.05345  0.02066  0.00674  231 ASP A CG  
1773 O OD1 . ASP A 231 ? 0.64955 0.51936 0.60890 0.05575  0.02402  0.00999  231 ASP A OD1 
1774 O OD2 . ASP A 231 ? 0.76341 0.63245 0.72785 0.04987  0.01961  0.00362  231 ASP A OD2 
1775 N N   . ASP A 232 ? 0.44883 0.43217 0.48883 0.04788  0.02048  0.00957  232 ASP A N   
1776 C CA  . ASP A 232 ? 0.43267 0.44048 0.48465 0.05103  0.02020  0.00826  232 ASP A CA  
1777 C C   . ASP A 232 ? 0.45028 0.47342 0.52172 0.04042  0.02160  0.01103  232 ASP A C   
1778 O O   . ASP A 232 ? 0.45625 0.47353 0.53364 0.03111  0.02204  0.01285  232 ASP A O   
1779 C CB  . ASP A 232 ? 0.44385 0.44948 0.48689 0.05630  0.01707  0.00439  232 ASP A CB  
1780 C CG  . ASP A 232 ? 0.52126 0.51307 0.56051 0.04918  0.01418  0.00393  232 ASP A CG  
1781 O OD1 . ASP A 232 ? 0.46862 0.46444 0.51981 0.03926  0.01427  0.00572  232 ASP A OD1 
1782 O OD2 . ASP A 232 ? 0.53918 0.51697 0.56428 0.05395  0.01141  0.00065  232 ASP A OD2 
1783 N N   . VAL A 233 ? 0.40691 0.44930 0.48789 0.04199  0.02276  0.01063  233 VAL A N   
1784 C CA  . VAL A 233 ? 0.41375 0.46897 0.50999 0.03400  0.02347  0.01311  233 VAL A CA  
1785 C C   . VAL A 233 ? 0.42752 0.48496 0.51877 0.03582  0.02187  0.01172  233 VAL A C   
1786 O O   . VAL A 233 ? 0.38367 0.44575 0.46843 0.04292  0.02376  0.00902  233 VAL A O   
1787 C CB  . VAL A 233 ? 0.42403 0.49834 0.53526 0.03356  0.02811  0.01460  233 VAL A CB  
1788 C CG1 . VAL A 233 ? 0.39300 0.47738 0.51824 0.02569  0.02849  0.01741  233 VAL A CG1 
1789 C CG2 . VAL A 233 ? 0.46444 0.53603 0.57789 0.03334  0.02951  0.01560  233 VAL A CG2 
1790 N N   . GLU A 234 ? 0.39974 0.45398 0.49350 0.02990  0.01831  0.01260  234 GLU A N   
1791 C CA  . GLU A 234 ? 0.35806 0.40969 0.44277 0.03223  0.01549  0.01118  234 GLU A CA  
1792 C C   . GLU A 234 ? 0.41487 0.47492 0.50746 0.02825  0.01519  0.01396  234 GLU A C   
1793 O O   . GLU A 234 ? 0.40077 0.46151 0.50358 0.02226  0.01212  0.01473  234 GLU A O   
1794 C CB  . GLU A 234 ? 0.37334 0.40935 0.44910 0.03131  0.00956  0.00781  234 GLU A CB  
1795 C CG  . GLU A 234 ? 0.40110 0.42413 0.46849 0.03393  0.01008  0.00578  234 GLU A CG  
1796 C CD  . GLU A 234 ? 0.47806 0.48463 0.53813 0.03139  0.00560  0.00182  234 GLU A CD  
1797 O OE1 . GLU A 234 ? 0.46582 0.47335 0.52834 0.02838  0.00118  -0.00047 234 GLU A OE1 
1798 O OE2 . GLU A 234 ? 0.55158 0.54332 0.60261 0.03288  0.00646  0.00038  234 GLU A OE2 
1799 N N   . LEU A 235 ? 0.36249 0.42792 0.44956 0.03166  0.01876  0.01488  235 LEU A N   
1800 C CA  . LEU A 235 ? 0.38864 0.45641 0.47624 0.02963  0.01852  0.01783  235 LEU A CA  
1801 C C   . LEU A 235 ? 0.41007 0.46697 0.48105 0.03335  0.01320  0.01600  235 LEU A C   
1802 O O   . LEU A 235 ? 0.38451 0.43846 0.44259 0.03821  0.01571  0.01404  235 LEU A O   
1803 C CB  . LEU A 235 ? 0.36389 0.44186 0.45405 0.03014  0.02775  0.01992  235 LEU A CB  
1804 C CG  . LEU A 235 ? 0.40739 0.48386 0.49309 0.02884  0.02993  0.02367  235 LEU A CG  
1805 C CD1 . LEU A 235 ? 0.40754 0.48403 0.50391 0.02458  0.02408  0.02636  235 LEU A CD1 
1806 C CD2 . LEU A 235 ? 0.42464 0.51089 0.51429 0.02791  0.04158  0.02425  235 LEU A CD2 
1807 N N   . ILE A 236 ? 0.36856 0.42051 0.44033 0.03157  0.00543  0.01543  236 ILE A N   
1808 C CA  . ILE A 236 ? 0.37773 0.41957 0.43570 0.03545  -0.00191 0.01167  236 ILE A CA  
1809 C C   . ILE A 236 ? 0.48817 0.52712 0.53879 0.03771  -0.00596 0.01358  236 ILE A C   
1810 O O   . ILE A 236 ? 0.42047 0.46334 0.48219 0.03468  -0.00897 0.01479  236 ILE A O   
1811 C CB  . ILE A 236 ? 0.39577 0.43320 0.46097 0.03226  -0.00894 0.00604  236 ILE A CB  
1812 C CG1 . ILE A 236 ? 0.41101 0.44621 0.47831 0.03113  -0.00455 0.00499  236 ILE A CG1 
1813 C CG2 . ILE A 236 ? 0.38940 0.41829 0.44236 0.03644  -0.01710 0.00056  236 ILE A CG2 
1814 C CD1 . ILE A 236 ? 0.44023 0.46819 0.51377 0.02624  -0.00857 -0.00009 236 ILE A CD1 
1815 N N   . HIS A 237 ? 0.40821 0.43928 0.43878 0.04367  -0.00631 0.01354  237 HIS A N   
1816 C CA  . HIS A 237 ? 0.45288 0.47671 0.47013 0.04791  -0.01081 0.01539  237 HIS A CA  
1817 C C   . HIS A 237 ? 0.45807 0.47373 0.46287 0.05355  -0.02126 0.00925  237 HIS A C   
1818 O O   . HIS A 237 ? 0.43673 0.44945 0.43363 0.05573  -0.02071 0.00583  237 HIS A O   
1819 C CB  . HIS A 237 ? 0.44807 0.46751 0.44917 0.05004  -0.00060 0.02111  237 HIS A CB  
1820 C CG  . HIS A 237 ? 0.51005 0.53664 0.52337 0.04488  0.00803  0.02636  237 HIS A CG  
1821 N ND1 . HIS A 237 ? 0.49953 0.53869 0.53096 0.03977  0.01508  0.02610  237 HIS A ND1 
1822 C CD2 . HIS A 237 ? 0.51396 0.53644 0.52414 0.04451  0.01012  0.03141  237 HIS A CD2 
1823 C CE1 . HIS A 237 ? 0.50876 0.55310 0.54926 0.03598  0.02145  0.03029  237 HIS A CE1 
1824 N NE2 . HIS A 237 ? 0.56339 0.59720 0.59134 0.03837  0.01895  0.03380  237 HIS A NE2 
1825 N N   . PHE A 238 ? 0.46356 0.47634 0.46731 0.05656  -0.03134 0.00680  238 PHE A N   
1826 C CA  . PHE A 238 ? 0.47817 0.48681 0.47621 0.06150  -0.04311 -0.00171 238 PHE A CA  
1827 C C   . PHE A 238 ? 0.53896 0.54081 0.52353 0.06945  -0.05232 -0.00224 238 PHE A C   
1828 O O   . PHE A 238 ? 0.51328 0.51561 0.50114 0.06901  -0.05163 0.00250  238 PHE A O   
1829 C CB  . PHE A 238 ? 0.47953 0.49636 0.50134 0.05508  -0.04848 -0.00982 238 PHE A CB  
1830 C CG  . PHE A 238 ? 0.46392 0.48967 0.50655 0.04930  -0.04946 -0.00930 238 PHE A CG  
1831 C CD1 . PHE A 238 ? 0.42478 0.45711 0.48140 0.04182  -0.03983 -0.00361 238 PHE A CD1 
1832 C CD2 . PHE A 238 ? 0.47654 0.50496 0.52488 0.05215  -0.06055 -0.01554 238 PHE A CD2 
1833 C CE1 . PHE A 238 ? 0.42195 0.46302 0.49776 0.03643  -0.04049 -0.00340 238 PHE A CE1 
1834 C CE2 . PHE A 238 ? 0.43344 0.47119 0.50196 0.04690  -0.06157 -0.01604 238 PHE A CE2 
1835 C CZ  . PHE A 238 ? 0.42802 0.47193 0.51023 0.03857  -0.05111 -0.00957 238 PHE A CZ  
1836 N N   . PRO A 239 ? 0.57183 0.56669 0.54038 0.07764  -0.06156 -0.00837 239 PRO A N   
1837 C CA  . PRO A 239 ? 0.59650 0.58320 0.54887 0.08764  -0.07194 -0.00968 239 PRO A CA  
1838 C C   . PRO A 239 ? 0.58236 0.57875 0.55592 0.08728  -0.08388 -0.01826 239 PRO A C   
1839 O O   . PRO A 239 ? 0.56626 0.57450 0.56434 0.08015  -0.08635 -0.02662 239 PRO A O   
1840 C CB  . PRO A 239 ? 0.63527 0.61377 0.56611 0.09648  -0.07839 -0.01544 239 PRO A CB  
1841 C CG  . PRO A 239 ? 0.68986 0.67657 0.63638 0.08971  -0.07594 -0.02154 239 PRO A CG  
1842 C CD  . PRO A 239 ? 0.60396 0.59639 0.56473 0.07952  -0.06231 -0.01380 239 PRO A CD  
1843 N N   . PHE A 240 ? 0.56606 0.55616 0.52883 0.09521  -0.09090 -0.01666 240 PHE A N   
1844 C CA  . PHE A 240 ? 0.60815 0.60815 0.59012 0.09671  -0.10346 -0.02618 240 PHE A CA  
1845 C C   . PHE A 240 ? 0.60569 0.61315 0.59580 0.10048  -0.11664 -0.04234 240 PHE A C   
1846 O O   . PHE A 240 ? 0.58551 0.60803 0.60482 0.09250  -0.11959 -0.05271 240 PHE A O   
1847 C CB  . PHE A 240 ? 0.58355 0.57178 0.54616 0.10786  -0.11021 -0.02205 240 PHE A CB  
1848 C CG  . PHE A 240 ? 0.58888 0.57230 0.55062 0.10279  -0.09843 -0.00889 240 PHE A CG  
1849 C CD1 . PHE A 240 ? 0.56052 0.55725 0.54874 0.08912  -0.08742 -0.00543 240 PHE A CD1 
1850 C CD2 . PHE A 240 ? 0.57906 0.54337 0.51234 0.11203  -0.09823 -0.00041 240 PHE A CD2 
1851 C CE1 . PHE A 240 ? 0.52081 0.51469 0.50977 0.08461  -0.07677 0.00531  240 PHE A CE1 
1852 C CE2 . PHE A 240 ? 0.61719 0.57662 0.55051 0.10661  -0.08647 0.01082  240 PHE A CE2 
1853 C CZ  . PHE A 240 ? 0.57748 0.55325 0.54020 0.09277  -0.07593 0.01316  240 PHE A CZ  
1854 N N   . LEU A 241 ? 0.63171 0.62851 0.59597 0.11240  -0.12417 -0.04544 241 LEU A N   
1855 C CA  . LEU A 241 ? 0.70007 0.70366 0.66955 0.11852  -0.13842 -0.06221 241 LEU A CA  
1856 C C   . LEU A 241 ? 0.74158 0.74469 0.70859 0.11474  -0.13353 -0.06514 241 LEU A C   
1857 O O   . LEU A 241 ? 0.70161 0.69663 0.65599 0.11089  -0.12087 -0.05387 241 LEU A O   
1858 C CB  . LEU A 241 ? 0.72608 0.71836 0.66746 0.13682  -0.15281 -0.06582 241 LEU A CB  
1859 C CG  . LEU A 241 ? 0.81113 0.79944 0.74777 0.14496  -0.16065 -0.06387 241 LEU A CG  
1860 C CD1 . LEU A 241 ? 0.69884 0.70752 0.67517 0.13471  -0.16250 -0.07193 241 LEU A CD1 
1861 C CD2 . LEU A 241 ? 0.77804 0.74630 0.68733 0.14652  -0.14893 -0.04449 241 LEU A CD2 
1862 N N   . GLU A 242 ? 0.79275 0.80536 0.77311 0.11600  -0.14391 -0.08187 242 GLU A N   
1863 C CA  . GLU A 242 ? 0.88272 0.89396 0.85981 0.11414  -0.14155 -0.08690 242 GLU A CA  
1864 C C   . GLU A 242 ? 0.91773 0.91365 0.85762 0.12700  -0.14321 -0.08099 242 GLU A C   
1865 O O   . GLU A 242 ? 0.94579 0.93761 0.86867 0.14094  -0.15639 -0.08740 242 GLU A O   
1866 C CB  . GLU A 242 ? 0.89025 0.91477 0.88967 0.11317  -0.15272 -0.10785 242 GLU A CB  
1867 N N   . GLU A 243 ? 0.98655 0.97379 0.91281 0.12295  -0.12993 -0.06939 243 GLU A N   
1868 C CA  . GLU A 243 ? 1.03561 1.00799 0.92631 0.13319  -0.12849 -0.06321 243 GLU A CA  
1869 C C   . GLU A 243 ? 1.07344 1.04809 0.96224 0.13635  -0.13421 -0.07501 243 GLU A C   
1870 O O   . GLU A 243 ? 1.06666 1.04254 0.96145 0.12887  -0.12544 -0.07409 243 GLU A O   
1871 C CB  . GLU A 243 ? 1.01942 0.98381 0.89883 0.12695  -0.11108 -0.04734 243 GLU A CB  
1872 C CG  . GLU A 243 ? 0.97979 0.94508 0.86848 0.12081  -0.10375 -0.03706 243 GLU A CG  
1873 C CD  . GLU A 243 ? 1.03020 0.97934 0.88864 0.12972  -0.10248 -0.02725 243 GLU A CD  
1874 O OE1 . GLU A 243 ? 1.05541 0.99899 0.90163 0.14107  -0.11582 -0.03218 243 GLU A OE1 
1875 O OE2 . GLU A 243 ? 1.16433 1.10558 1.01057 0.12568  -0.08803 -0.01541 243 GLU A OE2 
1876 N N   . ASN A 244 ? 1.08726 1.06245 0.96751 0.14844  -0.14976 -0.08704 244 ASN A N   
1877 C CA  . ASN A 244 ? 1.05926 1.03796 0.93898 0.15241  -0.15687 -0.10046 244 ASN A CA  
1878 C C   . ASN A 244 ? 1.08382 1.04934 0.93287 0.15726  -0.14958 -0.09233 244 ASN A C   
1879 O O   . ASN A 244 ? 1.08352 1.03541 0.89980 0.16837  -0.15088 -0.08527 244 ASN A O   
1880 C CB  . ASN A 244 ? 1.02769 1.01118 0.90456 0.16593  -0.17610 -0.11619 244 ASN A CB  
1881 C CG  . ASN A 244 ? 1.04270 1.04198 0.95269 0.16093  -0.18361 -0.12738 244 ASN A CG  
1882 O OD1 . ASN A 244 ? 1.01769 1.01624 0.92340 0.16822  -0.19111 -0.12643 244 ASN A OD1 
1883 N ND2 . ASN A 244 ? 1.05129 1.06387 0.99391 0.14818  -0.18097 -0.13834 244 ASN A ND2 
1884 N N   . LEU A 245 ? 1.01781 0.98621 0.87643 0.14899  -0.14151 -0.09362 245 LEU A N   
1885 C CA  . LEU A 245 ? 1.01186 0.97052 0.84494 0.15306  -0.13487 -0.08851 245 LEU A CA  
1886 C C   . LEU A 245 ? 0.98834 0.94308 0.79946 0.16764  -0.14799 -0.09881 245 LEU A C   
1887 O O   . LEU A 245 ? 0.95775 0.92196 0.78349 0.17101  -0.16099 -0.11467 245 LEU A O   
1888 C CB  . LEU A 245 ? 0.89148 0.85481 0.74156 0.14254  -0.12601 -0.09043 245 LEU A CB  
1889 C CG  . LEU A 245 ? 0.90131 0.85747 0.72979 0.14589  -0.11922 -0.08759 245 LEU A CG  
1890 N N   . TYR A 246 ? 0.93569 0.87640 0.71118 0.17630  -0.14414 -0.09051 246 TYR A N   
1891 C CA  . TYR A 246 ? 0.90399 0.83921 0.65438 0.19027  -0.15458 -0.09913 246 TYR A CA  
1892 C C   . TYR A 246 ? 0.93780 0.86102 0.65941 0.19137  -0.14213 -0.08975 246 TYR A C   
1893 O O   . TYR A 246 ? 0.99206 0.91008 0.70990 0.18334  -0.12666 -0.07650 246 TYR A O   
1894 C CB  . TYR A 246 ? 0.97040 0.89814 0.69993 0.20533  -0.16855 -0.10156 246 TYR A CB  
1895 C CG  . TYR A 246 ? 1.02200 0.92993 0.71796 0.20997  -0.16037 -0.08474 246 TYR A CG  
1896 C CD1 . TYR A 246 ? 1.05306 0.95959 0.75912 0.20360  -0.15488 -0.07491 246 TYR A CD1 
1897 C CD2 . TYR A 246 ? 1.06097 0.95042 0.71419 0.22048  -0.15755 -0.07919 246 TYR A CD2 
1898 C CE1 . TYR A 246 ? 1.16934 1.05604 0.84457 0.20715  -0.14641 -0.06000 246 TYR A CE1 
1899 C CE2 . TYR A 246 ? 1.13903 1.00737 0.75971 0.22368  -0.14828 -0.06405 246 TYR A CE2 
1900 C CZ  . TYR A 246 ? 1.21537 1.08211 0.84747 0.21690  -0.14268 -0.05457 246 TYR A CZ  
1901 O OH  . TYR A 246 ? 1.27107 1.11514 0.87063 0.21941  -0.13245 -0.03990 246 TYR A OH  
1902 N N   . PHE A 247 ? 0.83621 0.75644 0.53885 0.20121  -0.14881 -0.09809 247 PHE A N   
1903 C CA  . PHE A 247 ? 0.87993 0.79146 0.55839 0.20167  -0.13737 -0.09233 247 PHE A CA  
1904 C C   . PHE A 247 ? 1.00589 0.89898 0.63844 0.21618  -0.13989 -0.08820 247 PHE A C   
1905 O O   . PHE A 247 ? 0.99759 0.87953 0.60403 0.21607  -0.12733 -0.08035 247 PHE A O   
1906 C CB  . PHE A 247 ? 0.85244 0.77447 0.54529 0.19996  -0.14047 -0.10500 247 PHE A CB  
1907 C CG  . PHE A 247 ? 0.77069 0.70671 0.50474 0.18671  -0.13849 -0.10988 247 PHE A CG  
1908 C CD1 . PHE A 247 ? 0.80327 0.74059 0.55172 0.17434  -0.12424 -0.09907 247 PHE A CD1 
1909 C CD2 . PHE A 247 ? 0.76390 0.71070 0.52094 0.18677  -0.15032 -0.12600 247 PHE A CD2 
1910 C CE1 . PHE A 247 ? 0.72560 0.67247 0.50757 0.16317  -0.12224 -0.10298 247 PHE A CE1 
1911 C CE2 . PHE A 247 ? 0.72069 0.67638 0.51208 0.17406  -0.14691 -0.13009 247 PHE A CE2 
1912 C CZ  . PHE A 247 ? 0.69159 0.64616 0.49382 0.16270  -0.13301 -0.11792 247 PHE A CZ  
1913 N N   . HIS A 250 ? 1.13680 0.98679 0.65563 0.20575  -0.06663 -0.05891 250 HIS A N   
1914 C CA  . HIS A 250 ? 1.21017 1.05670 0.71553 0.19830  -0.04614 -0.05459 250 HIS A CA  
1915 C C   . HIS A 250 ? 1.23790 1.08963 0.73404 0.20288  -0.04748 -0.06514 250 HIS A C   
1916 O O   . HIS A 250 ? 1.21783 1.07570 0.71917 0.21144  -0.06423 -0.07539 250 HIS A O   
1917 C CB  . HIS A 250 ? 1.18747 1.04944 0.72832 0.18339  -0.03384 -0.05151 250 HIS A CB  
1918 C CG  . HIS A 250 ? 1.28281 1.14107 0.83417 0.17795  -0.03112 -0.04144 250 HIS A CG  
1919 N ND1 . HIS A 250 ? 1.25546 1.12371 0.83646 0.17723  -0.04436 -0.04301 250 HIS A ND1 
1920 C CD2 . HIS A 250 ? 1.28478 1.13043 0.82144 0.17246  -0.01604 -0.03033 250 HIS A CD2 
1921 C CE1 . HIS A 250 ? 1.20413 1.06693 0.78834 0.17219  -0.03839 -0.03315 250 HIS A CE1 
1922 N NE2 . HIS A 250 ? 1.26408 1.11282 0.82176 0.16931  -0.02136 -0.02522 250 HIS A NE2 
1923 N N   . HIS A 251 ? 1.25698 1.10711 0.74044 0.19695  -0.02952 -0.06379 251 HIS A N   
1924 C CA  . HIS A 251 ? 1.30357 1.15883 0.77738 0.20070  -0.02889 -0.07386 251 HIS A CA  
1925 C C   . HIS A 251 ? 1.30700 1.17407 0.79479 0.18901  -0.01027 -0.07547 251 HIS A C   
1926 O O   . HIS A 251 ? 1.30844 1.17401 0.80015 0.17927  0.00529  -0.06770 251 HIS A O   
1927 C CB  . HIS A 251 ? 1.31204 1.14558 0.73577 0.21168  -0.02804 -0.07249 251 HIS A CB  
1928 C CG  . HIS A 251 ? 1.33635 1.16110 0.74537 0.22655  -0.04930 -0.07525 251 HIS A CG  
1929 N ND1 . HIS A 251 ? 1.31361 1.12520 0.71370 0.23114  -0.05619 -0.06712 251 HIS A ND1 
1930 C CD2 . HIS A 251 ? 1.30313 1.13139 0.70535 0.23856  -0.06563 -0.08666 251 HIS A CD2 
1931 C CE1 . HIS A 251 ? 1.34698 1.15518 0.73585 0.24583  -0.07634 -0.07408 251 HIS A CE1 
1932 N NE2 . HIS A 251 ? 1.25922 1.07766 0.64942 0.25038  -0.08224 -0.08609 251 HIS A NE2 
1933 N N   . HIS A 252 ? 1.33881 1.21845 0.83480 0.19058  -0.01242 -0.08691 252 HIS A N   
1934 C CA  . HIS A 252 ? 1.37932 1.27246 0.88929 0.18169  0.00296  -0.09167 252 HIS A CA  
1935 C C   . HIS A 252 ? 1.40899 1.29212 0.88315 0.18187  0.01884  -0.09261 252 HIS A C   
1936 O O   . HIS A 252 ? 1.39487 1.28950 0.87307 0.18039  0.02503  -0.10246 252 HIS A O   
1937 C CB  . HIS A 252 ? 1.35400 1.26565 0.89314 0.18334  -0.00764 -0.10422 252 HIS A CB  
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