data_9CCX
# 
_entry.id   9CCX 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CCX         pdb_00009ccx 10.2210/pdb9ccx/pdb 
WWPDB D_1000285066 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-12 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CCX 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-23 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              peizhou@biochem.duke.edu 
_pdbx_contact_author.name_first         Pei 
_pdbx_contact_author.name_last          Zhou 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7823-3416 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Cochrane, C.S.' 1 ? 
'Zhou, P.'       2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Jacs Au' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2691-3704 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            4 
_citation.language                  ? 
_citation.page_first                4383 
_citation.page_last                 4393 
_citation.title                     
'Design and Evaluation of Pyridinyl Sulfonyl Piperazine LpxH Inhibitors with Potent Antibiotic Activity Against Enterobacterales.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/jacsau.4c00731 
_citation.pdbx_database_id_PubMed   39610720 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Ennis, A.F.'    1  ?                   
primary 'Cochrane, C.S.' 2  ?                   
primary 'Dome, P.A.'     3  ?                   
primary 'Jeong, P.'      4  ?                   
primary 'Yu, J.'         5  0000-0001-8487-5565 
primary 'Lee, H.'        6  ?                   
primary 'Williams, C.S.' 7  ?                   
primary 'Ha, Y.'         8  0000-0001-5684-8420 
primary 'Yang, W.'       9  0000-0001-5576-2828 
primary 'Zhou, P.'       10 0000-0002-7823-3416 
primary 'Hong, J.'       11 0000-0002-5253-0949 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'UDP-2,3-diacylglucosamine hydrolase'                                                                   
29627.680 1  3.6.1.54 ? ? ? 
2 non-polymer syn '1-(5-{4-[4-(trifluoromethyl)pyridin-2-yl]piperazine-1-sulfonyl}-2,3-dihydro-1H-indol-1-yl)ethan-1-one' 454.466 
1  ?        ? ? ? 
3 non-polymer syn 'TETRAETHYLENE GLYCOL'                                                                                  194.226 
1  ?        ? ? ? 
4 non-polymer syn 'MANGANESE (II) ION'                                                                                    54.938 2 
?        ? ? ? 
5 water       nat water                                                                                                   18.015 
41 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'UDP-2,3-diacylglucosamine diphosphatase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MATLFIADLHLQTEEPAITAGFLRFLQGEARQADALYILGDLFEAWIGDDDPNPLHQQIASAIKAVVDAGVPCYFIHGNR
DFLVGQRFARQSGMILLAEEERLDLYGREVLIMHGDTLCTDDQGYLAFRAKVHTPWIQRLFLALPLFIRHRIAARMRADS
KAANSSKSMEIMDVNPQAVVDAMERHHVQWLIHGHTHRPAVHELQANGQPAWRVVLGAWHSEGSMVKVTPDDVELIHFPF
LEENLYFQSHHHHHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MATLFIADLHLQTEEPAITAGFLRFLQGEARQADALYILGDLFEAWIGDDDPNPLHQQIASAIKAVVDAGVPCYFIHGNR
DFLVGQRFARQSGMILLAEEERLDLYGREVLIMHGDTLCTDDQGYLAFRAKVHTPWIQRLFLALPLFIRHRIAARMRADS
KAANSSKSMEIMDVNPQAVVDAMERHHVQWLIHGHTHRPAVHELQANGQPAWRVVLGAWHSEGSMVKVTPDDVELIHFPF
LEENLYFQSHHHHHHHHHH
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '1-(5-{4-[4-(trifluoromethyl)pyridin-2-yl]piperazine-1-sulfonyl}-2,3-dihydro-1H-indol-1-yl)ethan-1-one' A1AVZ 
3 'TETRAETHYLENE GLYCOL'                                                                                  PG4   
4 'MANGANESE (II) ION'                                                                                    MN    
5 water                                                                                                   HOH   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   THR n 
1 4   LEU n 
1 5   PHE n 
1 6   ILE n 
1 7   ALA n 
1 8   ASP n 
1 9   LEU n 
1 10  HIS n 
1 11  LEU n 
1 12  GLN n 
1 13  THR n 
1 14  GLU n 
1 15  GLU n 
1 16  PRO n 
1 17  ALA n 
1 18  ILE n 
1 19  THR n 
1 20  ALA n 
1 21  GLY n 
1 22  PHE n 
1 23  LEU n 
1 24  ARG n 
1 25  PHE n 
1 26  LEU n 
1 27  GLN n 
1 28  GLY n 
1 29  GLU n 
1 30  ALA n 
1 31  ARG n 
1 32  GLN n 
1 33  ALA n 
1 34  ASP n 
1 35  ALA n 
1 36  LEU n 
1 37  TYR n 
1 38  ILE n 
1 39  LEU n 
1 40  GLY n 
1 41  ASP n 
1 42  LEU n 
1 43  PHE n 
1 44  GLU n 
1 45  ALA n 
1 46  TRP n 
1 47  ILE n 
1 48  GLY n 
1 49  ASP n 
1 50  ASP n 
1 51  ASP n 
1 52  PRO n 
1 53  ASN n 
1 54  PRO n 
1 55  LEU n 
1 56  HIS n 
1 57  GLN n 
1 58  GLN n 
1 59  ILE n 
1 60  ALA n 
1 61  SER n 
1 62  ALA n 
1 63  ILE n 
1 64  LYS n 
1 65  ALA n 
1 66  VAL n 
1 67  VAL n 
1 68  ASP n 
1 69  ALA n 
1 70  GLY n 
1 71  VAL n 
1 72  PRO n 
1 73  CYS n 
1 74  TYR n 
1 75  PHE n 
1 76  ILE n 
1 77  HIS n 
1 78  GLY n 
1 79  ASN n 
1 80  ARG n 
1 81  ASP n 
1 82  PHE n 
1 83  LEU n 
1 84  VAL n 
1 85  GLY n 
1 86  GLN n 
1 87  ARG n 
1 88  PHE n 
1 89  ALA n 
1 90  ARG n 
1 91  GLN n 
1 92  SER n 
1 93  GLY n 
1 94  MET n 
1 95  ILE n 
1 96  LEU n 
1 97  LEU n 
1 98  ALA n 
1 99  GLU n 
1 100 GLU n 
1 101 GLU n 
1 102 ARG n 
1 103 LEU n 
1 104 ASP n 
1 105 LEU n 
1 106 TYR n 
1 107 GLY n 
1 108 ARG n 
1 109 GLU n 
1 110 VAL n 
1 111 LEU n 
1 112 ILE n 
1 113 MET n 
1 114 HIS n 
1 115 GLY n 
1 116 ASP n 
1 117 THR n 
1 118 LEU n 
1 119 CYS n 
1 120 THR n 
1 121 ASP n 
1 122 ASP n 
1 123 GLN n 
1 124 GLY n 
1 125 TYR n 
1 126 LEU n 
1 127 ALA n 
1 128 PHE n 
1 129 ARG n 
1 130 ALA n 
1 131 LYS n 
1 132 VAL n 
1 133 HIS n 
1 134 THR n 
1 135 PRO n 
1 136 TRP n 
1 137 ILE n 
1 138 GLN n 
1 139 ARG n 
1 140 LEU n 
1 141 PHE n 
1 142 LEU n 
1 143 ALA n 
1 144 LEU n 
1 145 PRO n 
1 146 LEU n 
1 147 PHE n 
1 148 ILE n 
1 149 ARG n 
1 150 HIS n 
1 151 ARG n 
1 152 ILE n 
1 153 ALA n 
1 154 ALA n 
1 155 ARG n 
1 156 MET n 
1 157 ARG n 
1 158 ALA n 
1 159 ASP n 
1 160 SER n 
1 161 LYS n 
1 162 ALA n 
1 163 ALA n 
1 164 ASN n 
1 165 SER n 
1 166 SER n 
1 167 LYS n 
1 168 SER n 
1 169 MET n 
1 170 GLU n 
1 171 ILE n 
1 172 MET n 
1 173 ASP n 
1 174 VAL n 
1 175 ASN n 
1 176 PRO n 
1 177 GLN n 
1 178 ALA n 
1 179 VAL n 
1 180 VAL n 
1 181 ASP n 
1 182 ALA n 
1 183 MET n 
1 184 GLU n 
1 185 ARG n 
1 186 HIS n 
1 187 HIS n 
1 188 VAL n 
1 189 GLN n 
1 190 TRP n 
1 191 LEU n 
1 192 ILE n 
1 193 HIS n 
1 194 GLY n 
1 195 HIS n 
1 196 THR n 
1 197 HIS n 
1 198 ARG n 
1 199 PRO n 
1 200 ALA n 
1 201 VAL n 
1 202 HIS n 
1 203 GLU n 
1 204 LEU n 
1 205 GLN n 
1 206 ALA n 
1 207 ASN n 
1 208 GLY n 
1 209 GLN n 
1 210 PRO n 
1 211 ALA n 
1 212 TRP n 
1 213 ARG n 
1 214 VAL n 
1 215 VAL n 
1 216 LEU n 
1 217 GLY n 
1 218 ALA n 
1 219 TRP n 
1 220 HIS n 
1 221 SER n 
1 222 GLU n 
1 223 GLY n 
1 224 SER n 
1 225 MET n 
1 226 VAL n 
1 227 LYS n 
1 228 VAL n 
1 229 THR n 
1 230 PRO n 
1 231 ASP n 
1 232 ASP n 
1 233 VAL n 
1 234 GLU n 
1 235 LEU n 
1 236 ILE n 
1 237 HIS n 
1 238 PHE n 
1 239 PRO n 
1 240 PHE n 
1 241 LEU n 
1 242 GLU n 
1 243 GLU n 
1 244 ASN n 
1 245 LEU n 
1 246 TYR n 
1 247 PHE n 
1 248 GLN n 
1 249 SER n 
1 250 HIS n 
1 251 HIS n 
1 252 HIS n 
1 253 HIS n 
1 254 HIS n 
1 255 HIS n 
1 256 HIS n 
1 257 HIS n 
1 258 HIS n 
1 259 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   259 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'lpxH_1, lpxH, C3483_19950, NCTC9128_00880, SAMEA104305404_03891' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Klebsiella pneumoniae' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     573 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1AVZ non-polymer         . 
'1-(5-{4-[4-(trifluoromethyl)pyridin-2-yl]piperazine-1-sulfonyl}-2,3-dihydro-1H-indol-1-yl)ethan-1-one' ? 'C20 H21 F3 N4 O3 S' 
454.466 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'         89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1'     175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'        132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'         133.103 
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'       121.158 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'       146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'         147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'         75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1'     156.162 
HOH   non-polymer         . WATER ? 'H2 O'               18.015  
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'        131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'        131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1'     147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'      149.211 
MN    non-polymer         . 'MANGANESE (II) ION' ? 'Mn 2'               54.938  
PG4   non-polymer         . 'TETRAETHYLENE GLYCOL' ? 'C8 H18 O5'          194.226 
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'        165.189 
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'         115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'         105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'         119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'      204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'        181.189 
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'        117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   2   ALA ALA A . n 
A 1 3   THR 3   3   3   THR THR A . n 
A 1 4   LEU 4   4   4   LEU LEU A . n 
A 1 5   PHE 5   5   5   PHE PHE A . n 
A 1 6   ILE 6   6   6   ILE ILE A . n 
A 1 7   ALA 7   7   7   ALA ALA A . n 
A 1 8   ASP 8   8   8   ASP ASP A . n 
A 1 9   LEU 9   9   9   LEU LEU A . n 
A 1 10  HIS 10  10  10  HIS HIS A . n 
A 1 11  LEU 11  11  11  LEU LEU A . n 
A 1 12  GLN 12  12  12  GLN GLN A . n 
A 1 13  THR 13  13  13  THR THR A . n 
A 1 14  GLU 14  14  14  GLU GLU A . n 
A 1 15  GLU 15  15  15  GLU GLU A . n 
A 1 16  PRO 16  16  16  PRO PRO A . n 
A 1 17  ALA 17  17  17  ALA ALA A . n 
A 1 18  ILE 18  18  18  ILE ILE A . n 
A 1 19  THR 19  19  19  THR THR A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  GLY 21  21  21  GLY GLY A . n 
A 1 22  PHE 22  22  22  PHE PHE A . n 
A 1 23  LEU 23  23  23  LEU LEU A . n 
A 1 24  ARG 24  24  24  ARG ARG A . n 
A 1 25  PHE 25  25  25  PHE PHE A . n 
A 1 26  LEU 26  26  26  LEU LEU A . n 
A 1 27  GLN 27  27  27  GLN GLN A . n 
A 1 28  GLY 28  28  28  GLY GLY A . n 
A 1 29  GLU 29  29  29  GLU GLU A . n 
A 1 30  ALA 30  30  30  ALA ALA A . n 
A 1 31  ARG 31  31  31  ARG ARG A . n 
A 1 32  GLN 32  32  32  GLN GLN A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  ASP 34  34  34  ASP ASP A . n 
A 1 35  ALA 35  35  35  ALA ALA A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  TYR 37  37  37  TYR TYR A . n 
A 1 38  ILE 38  38  38  ILE ILE A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  GLY 40  40  40  GLY GLY A . n 
A 1 41  ASP 41  41  41  ASP ASP A . n 
A 1 42  LEU 42  42  42  LEU LEU A . n 
A 1 43  PHE 43  43  43  PHE PHE A . n 
A 1 44  GLU 44  44  44  GLU GLU A . n 
A 1 45  ALA 45  45  45  ALA ALA A . n 
A 1 46  TRP 46  46  46  TRP TRP A . n 
A 1 47  ILE 47  47  47  ILE ILE A . n 
A 1 48  GLY 48  48  48  GLY GLY A . n 
A 1 49  ASP 49  49  49  ASP ASP A . n 
A 1 50  ASP 50  50  50  ASP ASP A . n 
A 1 51  ASP 51  51  51  ASP ASP A . n 
A 1 52  PRO 52  52  52  PRO PRO A . n 
A 1 53  ASN 53  53  53  ASN ASN A . n 
A 1 54  PRO 54  54  54  PRO PRO A . n 
A 1 55  LEU 55  55  55  LEU LEU A . n 
A 1 56  HIS 56  56  56  HIS HIS A . n 
A 1 57  GLN 57  57  57  GLN GLN A . n 
A 1 58  GLN 58  58  58  GLN GLN A . n 
A 1 59  ILE 59  59  59  ILE ILE A . n 
A 1 60  ALA 60  60  60  ALA ALA A . n 
A 1 61  SER 61  61  61  SER SER A . n 
A 1 62  ALA 62  62  62  ALA ALA A . n 
A 1 63  ILE 63  63  63  ILE ILE A . n 
A 1 64  LYS 64  64  64  LYS LYS A . n 
A 1 65  ALA 65  65  65  ALA ALA A . n 
A 1 66  VAL 66  66  66  VAL VAL A . n 
A 1 67  VAL 67  67  67  VAL VAL A . n 
A 1 68  ASP 68  68  68  ASP ASP A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  VAL 71  71  71  VAL VAL A . n 
A 1 72  PRO 72  72  72  PRO PRO A . n 
A 1 73  CYS 73  73  73  CYS CYS A . n 
A 1 74  TYR 74  74  74  TYR TYR A . n 
A 1 75  PHE 75  75  75  PHE PHE A . n 
A 1 76  ILE 76  76  76  ILE ILE A . n 
A 1 77  HIS 77  77  77  HIS HIS A . n 
A 1 78  GLY 78  78  78  GLY GLY A . n 
A 1 79  ASN 79  79  79  ASN ASN A . n 
A 1 80  ARG 80  80  80  ARG ARG A . n 
A 1 81  ASP 81  81  81  ASP ASP A . n 
A 1 82  PHE 82  82  82  PHE PHE A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  GLY 85  85  85  GLY GLY A . n 
A 1 86  GLN 86  86  86  GLN GLN A . n 
A 1 87  ARG 87  87  87  ARG ARG A . n 
A 1 88  PHE 88  88  88  PHE PHE A . n 
A 1 89  ALA 89  89  89  ALA ALA A . n 
A 1 90  ARG 90  90  90  ARG ARG A . n 
A 1 91  GLN 91  91  91  GLN GLN A . n 
A 1 92  SER 92  92  92  SER SER A . n 
A 1 93  GLY 93  93  93  GLY GLY A . n 
A 1 94  MET 94  94  94  MET MET A . n 
A 1 95  ILE 95  95  95  ILE ILE A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  GLU 99  99  99  GLU GLU A . n 
A 1 100 GLU 100 100 100 GLU GLU A . n 
A 1 101 GLU 101 101 101 GLU GLU A . n 
A 1 102 ARG 102 102 102 ARG ARG A . n 
A 1 103 LEU 103 103 103 LEU LEU A . n 
A 1 104 ASP 104 104 104 ASP ASP A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 TYR 106 106 106 TYR TYR A . n 
A 1 107 GLY 107 107 107 GLY GLY A . n 
A 1 108 ARG 108 108 108 ARG ARG A . n 
A 1 109 GLU 109 109 109 GLU GLU A . n 
A 1 110 VAL 110 110 110 VAL VAL A . n 
A 1 111 LEU 111 111 111 LEU LEU A . n 
A 1 112 ILE 112 112 112 ILE ILE A . n 
A 1 113 MET 113 113 113 MET MET A . n 
A 1 114 HIS 114 114 114 HIS HIS A . n 
A 1 115 GLY 115 115 115 GLY GLY A . n 
A 1 116 ASP 116 116 116 ASP ASP A . n 
A 1 117 THR 117 117 117 THR THR A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 CYS 119 119 119 CYS CYS A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 ASP 121 121 121 ASP ASP A . n 
A 1 122 ASP 122 122 122 ASP ASP A . n 
A 1 123 GLN 123 123 123 GLN GLN A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 TYR 125 125 125 TYR TYR A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 ALA 127 127 127 ALA ALA A . n 
A 1 128 PHE 128 128 128 PHE PHE A . n 
A 1 129 ARG 129 129 129 ARG ARG A . n 
A 1 130 ALA 130 130 130 ALA ALA A . n 
A 1 131 LYS 131 131 131 LYS LYS A . n 
A 1 132 VAL 132 132 132 VAL VAL A . n 
A 1 133 HIS 133 133 133 HIS HIS A . n 
A 1 134 THR 134 134 134 THR THR A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 TRP 136 136 136 TRP TRP A . n 
A 1 137 ILE 137 137 137 ILE ILE A . n 
A 1 138 GLN 138 138 138 GLN GLN A . n 
A 1 139 ARG 139 139 139 ARG ARG A . n 
A 1 140 LEU 140 140 140 LEU LEU A . n 
A 1 141 PHE 141 141 141 PHE PHE A . n 
A 1 142 LEU 142 142 142 LEU LEU A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 LEU 144 144 144 LEU LEU A . n 
A 1 145 PRO 145 145 145 PRO PRO A . n 
A 1 146 LEU 146 146 146 LEU LEU A . n 
A 1 147 PHE 147 147 147 PHE PHE A . n 
A 1 148 ILE 148 148 148 ILE ILE A . n 
A 1 149 ARG 149 149 149 ARG ARG A . n 
A 1 150 HIS 150 150 150 HIS HIS A . n 
A 1 151 ARG 151 151 151 ARG ARG A . n 
A 1 152 ILE 152 152 152 ILE ILE A . n 
A 1 153 ALA 153 153 153 ALA ALA A . n 
A 1 154 ALA 154 154 154 ALA ALA A . n 
A 1 155 ARG 155 155 155 ARG ARG A . n 
A 1 156 MET 156 156 156 MET MET A . n 
A 1 157 ARG 157 157 157 ARG ARG A . n 
A 1 158 ALA 158 158 158 ALA ALA A . n 
A 1 159 ASP 159 159 159 ASP ASP A . n 
A 1 160 SER 160 160 160 SER SER A . n 
A 1 161 LYS 161 161 161 LYS LYS A . n 
A 1 162 ALA 162 162 162 ALA ALA A . n 
A 1 163 ALA 163 163 163 ALA ALA A . n 
A 1 164 ASN 164 164 164 ASN ASN A . n 
A 1 165 SER 165 165 ?   ?   ?   A . n 
A 1 166 SER 166 166 ?   ?   ?   A . n 
A 1 167 LYS 167 167 ?   ?   ?   A . n 
A 1 168 SER 168 168 ?   ?   ?   A . n 
A 1 169 MET 169 169 ?   ?   ?   A . n 
A 1 170 GLU 170 170 ?   ?   ?   A . n 
A 1 171 ILE 171 171 ?   ?   ?   A . n 
A 1 172 MET 172 172 172 MET MET A . n 
A 1 173 ASP 173 173 173 ASP ASP A . n 
A 1 174 VAL 174 174 174 VAL VAL A . n 
A 1 175 ASN 175 175 175 ASN ASN A . n 
A 1 176 PRO 176 176 176 PRO PRO A . n 
A 1 177 GLN 177 177 177 GLN GLN A . n 
A 1 178 ALA 178 178 178 ALA ALA A . n 
A 1 179 VAL 179 179 179 VAL VAL A . n 
A 1 180 VAL 180 180 180 VAL VAL A . n 
A 1 181 ASP 181 181 181 ASP ASP A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 MET 183 183 183 MET MET A . n 
A 1 184 GLU 184 184 184 GLU GLU A . n 
A 1 185 ARG 185 185 185 ARG ARG A . n 
A 1 186 HIS 186 186 186 HIS HIS A . n 
A 1 187 HIS 187 187 187 HIS HIS A . n 
A 1 188 VAL 188 188 188 VAL VAL A . n 
A 1 189 GLN 189 189 189 GLN GLN A . n 
A 1 190 TRP 190 190 190 TRP TRP A . n 
A 1 191 LEU 191 191 191 LEU LEU A . n 
A 1 192 ILE 192 192 192 ILE ILE A . n 
A 1 193 HIS 193 193 193 HIS HIS A . n 
A 1 194 GLY 194 194 194 GLY GLY A . n 
A 1 195 HIS 195 195 195 HIS HIS A . n 
A 1 196 THR 196 196 196 THR THR A . n 
A 1 197 HIS 197 197 197 HIS HIS A . n 
A 1 198 ARG 198 198 198 ARG ARG A . n 
A 1 199 PRO 199 199 199 PRO PRO A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 VAL 201 201 201 VAL VAL A . n 
A 1 202 HIS 202 202 202 HIS HIS A . n 
A 1 203 GLU 203 203 203 GLU GLU A . n 
A 1 204 LEU 204 204 204 LEU LEU A . n 
A 1 205 GLN 205 205 205 GLN GLN A . n 
A 1 206 ALA 206 206 206 ALA ALA A . n 
A 1 207 ASN 207 207 207 ASN ASN A . n 
A 1 208 GLY 208 208 208 GLY GLY A . n 
A 1 209 GLN 209 209 209 GLN GLN A . n 
A 1 210 PRO 210 210 210 PRO PRO A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 TRP 212 212 212 TRP TRP A . n 
A 1 213 ARG 213 213 213 ARG ARG A . n 
A 1 214 VAL 214 214 214 VAL VAL A . n 
A 1 215 VAL 215 215 215 VAL VAL A . n 
A 1 216 LEU 216 216 216 LEU LEU A . n 
A 1 217 GLY 217 217 217 GLY GLY A . n 
A 1 218 ALA 218 218 218 ALA ALA A . n 
A 1 219 TRP 219 219 219 TRP TRP A . n 
A 1 220 HIS 220 220 220 HIS HIS A . n 
A 1 221 SER 221 221 221 SER SER A . n 
A 1 222 GLU 222 222 222 GLU GLU A . n 
A 1 223 GLY 223 223 223 GLY GLY A . n 
A 1 224 SER 224 224 224 SER SER A . n 
A 1 225 MET 225 225 225 MET MET A . n 
A 1 226 VAL 226 226 226 VAL VAL A . n 
A 1 227 LYS 227 227 227 LYS LYS A . n 
A 1 228 VAL 228 228 228 VAL VAL A . n 
A 1 229 THR 229 229 229 THR THR A . n 
A 1 230 PRO 230 230 230 PRO PRO A . n 
A 1 231 ASP 231 231 231 ASP ASP A . n 
A 1 232 ASP 232 232 232 ASP ASP A . n 
A 1 233 VAL 233 233 233 VAL VAL A . n 
A 1 234 GLU 234 234 234 GLU GLU A . n 
A 1 235 LEU 235 235 235 LEU LEU A . n 
A 1 236 ILE 236 236 236 ILE ILE A . n 
A 1 237 HIS 237 237 237 HIS HIS A . n 
A 1 238 PHE 238 238 238 PHE PHE A . n 
A 1 239 PRO 239 239 239 PRO PRO A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 LEU 241 241 241 LEU LEU A . n 
A 1 242 GLU 242 242 242 GLU GLU A . n 
A 1 243 GLU 243 243 243 GLU GLU A . n 
A 1 244 ASN 244 244 244 ASN ASN A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 TYR 246 246 246 TYR TYR A . n 
A 1 247 PHE 247 247 247 PHE PHE A . n 
A 1 248 GLN 248 248 248 GLN GLN A . n 
A 1 249 SER 249 249 249 SER SER A . n 
A 1 250 HIS 250 250 250 HIS HIS A . n 
A 1 251 HIS 251 251 251 HIS HIS A . n 
A 1 252 HIS 252 252 252 HIS HIS A . n 
A 1 253 HIS 253 253 ?   ?   ?   A . n 
A 1 254 HIS 254 254 ?   ?   ?   A . n 
A 1 255 HIS 255 255 ?   ?   ?   A . n 
A 1 256 HIS 256 256 ?   ?   ?   A . n 
A 1 257 HIS 257 257 ?   ?   ?   A . n 
A 1 258 HIS 258 258 ?   ?   ?   A . n 
A 1 259 HIS 259 259 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        A1AVZ 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   A1AVZ 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 A1AVZ 1  301 301 A1AVZ LIG A . 
C 3 PG4   1  302 302 PG4   PG4 A . 
D 4 MN    1  303 1   MN    MN  A . 
E 4 MN    1  304 2   MN    MN  A . 
F 5 HOH   1  401 15  HOH   HOH A . 
F 5 HOH   2  402 39  HOH   HOH A . 
F 5 HOH   3  403 33  HOH   HOH A . 
F 5 HOH   4  404 10  HOH   HOH A . 
F 5 HOH   5  405 11  HOH   HOH A . 
F 5 HOH   6  406 12  HOH   HOH A . 
F 5 HOH   7  407 1   HOH   HOH A . 
F 5 HOH   8  408 2   HOH   HOH A . 
F 5 HOH   9  409 21  HOH   HOH A . 
F 5 HOH   10 410 13  HOH   HOH A . 
F 5 HOH   11 411 9   HOH   HOH A . 
F 5 HOH   12 412 17  HOH   HOH A . 
F 5 HOH   13 413 14  HOH   HOH A . 
F 5 HOH   14 414 27  HOH   HOH A . 
F 5 HOH   15 415 19  HOH   HOH A . 
F 5 HOH   16 416 5   HOH   HOH A . 
F 5 HOH   17 417 24  HOH   HOH A . 
F 5 HOH   18 418 22  HOH   HOH A . 
F 5 HOH   19 419 18  HOH   HOH A . 
F 5 HOH   20 420 28  HOH   HOH A . 
F 5 HOH   21 421 8   HOH   HOH A . 
F 5 HOH   22 422 26  HOH   HOH A . 
F 5 HOH   23 423 31  HOH   HOH A . 
F 5 HOH   24 424 23  HOH   HOH A . 
F 5 HOH   25 425 30  HOH   HOH A . 
F 5 HOH   26 426 4   HOH   HOH A . 
F 5 HOH   27 427 34  HOH   HOH A . 
F 5 HOH   28 428 7   HOH   HOH A . 
F 5 HOH   29 429 25  HOH   HOH A . 
F 5 HOH   30 430 6   HOH   HOH A . 
F 5 HOH   31 431 29  HOH   HOH A . 
F 5 HOH   32 432 38  HOH   HOH A . 
F 5 HOH   33 433 37  HOH   HOH A . 
F 5 HOH   34 434 3   HOH   HOH A . 
F 5 HOH   35 435 20  HOH   HOH A . 
F 5 HOH   36 436 16  HOH   HOH A . 
F 5 HOH   37 437 43  HOH   HOH A . 
F 5 HOH   38 438 35  HOH   HOH A . 
F 5 HOH   39 439 41  HOH   HOH A . 
F 5 HOH   40 440 40  HOH   HOH A . 
F 5 HOH   41 441 36  HOH   HOH A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ARG 24  ? NE  ? A ARG 24  NE  
2  1 Y 1 A ARG 24  ? CZ  ? A ARG 24  CZ  
3  1 Y 1 A ARG 24  ? NH1 ? A ARG 24  NH1 
4  1 Y 1 A ARG 24  ? NH2 ? A ARG 24  NH2 
5  1 Y 1 A GLN 27  ? CG  ? A GLN 27  CG  
6  1 Y 1 A GLN 27  ? CD  ? A GLN 27  CD  
7  1 Y 1 A GLN 27  ? OE1 ? A GLN 27  OE1 
8  1 Y 1 A GLN 27  ? NE2 ? A GLN 27  NE2 
9  1 Y 1 A GLU 29  ? CG  ? A GLU 29  CG  
10 1 Y 1 A GLU 29  ? CD  ? A GLU 29  CD  
11 1 Y 1 A GLU 29  ? OE1 ? A GLU 29  OE1 
12 1 Y 1 A GLU 29  ? OE2 ? A GLU 29  OE2 
13 1 Y 1 A SER 61  ? OG  ? A SER 61  OG  
14 1 Y 1 A ARG 90  ? CG  ? A ARG 90  CG  
15 1 Y 1 A ARG 90  ? CD  ? A ARG 90  CD  
16 1 Y 1 A ARG 90  ? NE  ? A ARG 90  NE  
17 1 Y 1 A ARG 90  ? CZ  ? A ARG 90  CZ  
18 1 Y 1 A ARG 90  ? NH1 ? A ARG 90  NH1 
19 1 Y 1 A ARG 90  ? NH2 ? A ARG 90  NH2 
20 1 Y 1 A GLN 91  ? CD  ? A GLN 91  CD  
21 1 Y 1 A GLN 91  ? OE1 ? A GLN 91  OE1 
22 1 Y 1 A GLN 91  ? NE2 ? A GLN 91  NE2 
23 1 Y 1 A GLU 109 ? CG  ? A GLU 109 CG  
24 1 Y 1 A GLU 109 ? CD  ? A GLU 109 CD  
25 1 Y 1 A GLU 109 ? OE1 ? A GLU 109 OE1 
26 1 Y 1 A GLU 109 ? OE2 ? A GLU 109 OE2 
27 1 Y 1 A LYS 161 ? CG  ? A LYS 161 CG  
28 1 Y 1 A LYS 161 ? CD  ? A LYS 161 CD  
29 1 Y 1 A LYS 161 ? CE  ? A LYS 161 CE  
30 1 Y 1 A LYS 161 ? NZ  ? A LYS 161 NZ  
31 1 Y 1 A ASN 164 ? CG  ? A ASN 164 CG  
32 1 Y 1 A ASN 164 ? OD1 ? A ASN 164 OD1 
33 1 Y 1 A ASN 164 ? ND2 ? A ASN 164 ND2 
34 1 Y 1 A GLN 177 ? CG  ? A GLN 177 CG  
35 1 Y 1 A GLN 177 ? CD  ? A GLN 177 CD  
36 1 Y 1 A GLN 177 ? OE1 ? A GLN 177 OE1 
37 1 Y 1 A GLN 177 ? NE2 ? A GLN 177 NE2 
38 1 Y 1 A GLU 184 ? CG  ? A GLU 184 CG  
39 1 Y 1 A GLU 184 ? CD  ? A GLU 184 CD  
40 1 Y 1 A GLU 184 ? OE1 ? A GLU 184 OE1 
41 1 Y 1 A GLU 184 ? OE2 ? A GLU 184 OE2 
42 1 Y 1 A GLN 205 ? CG  ? A GLN 205 CG  
43 1 Y 1 A GLN 205 ? CD  ? A GLN 205 CD  
44 1 Y 1 A GLN 205 ? OE1 ? A GLN 205 OE1 
45 1 Y 1 A GLN 205 ? NE2 ? A GLN 205 NE2 
46 1 Y 1 A GLN 209 ? CG  ? A GLN 209 CG  
47 1 Y 1 A GLN 209 ? CD  ? A GLN 209 CD  
48 1 Y 1 A GLN 209 ? OE1 ? A GLN 209 OE1 
49 1 Y 1 A GLN 209 ? NE2 ? A GLN 209 NE2 
50 1 Y 1 A GLU 242 ? CG  ? A GLU 242 CG  
51 1 Y 1 A GLU 242 ? CD  ? A GLU 242 CD  
52 1 Y 1 A GLU 242 ? OE1 ? A GLU 242 OE1 
53 1 Y 1 A GLU 242 ? OE2 ? A GLU 242 OE2 
54 1 Y 1 A LEU 245 ? CD1 ? A LEU 245 CD1 
55 1 Y 1 A LEU 245 ? CD2 ? A LEU 245 CD2 
56 1 Y 1 A GLN 248 ? CG  ? A GLN 248 CG  
57 1 Y 1 A GLN 248 ? CD  ? A GLN 248 CD  
58 1 Y 1 A GLN 248 ? OE1 ? A GLN 248 OE1 
59 1 Y 1 A GLN 248 ? NE2 ? A GLN 248 NE2 
60 1 Y 1 A SER 249 ? OG  ? A SER 249 OG  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XSCALE ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CCX 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     106.630 
_cell.length_a_esd                 ? 
_cell.length_b                     106.630 
_cell.length_b_esd                 ? 
_cell.length_c                     54.270 
_cell.length_c_esd                 ? 
_cell.volume                       534378.863 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CCX 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                154 
_symmetry.space_group_name_Hall            
;P 32 2"
;
_symmetry.space_group_name_H-M             'P 32 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CCX 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.01 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          59.08 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;1 mg/mL of LpxH,
0.14 mM LPH-86, 
10 mM MES (pH 6.0), 
100 mM NaCl, 
0.5 mM DTT, 
2.5% glycerol, 
0.8% DMSO, 
0.05 M sodium acetate pH 5.0, 
and 18 % v/v PEG 400
;
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-02-14 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.979180 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 24-ID-E' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.979180 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   24-ID-E 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          42.44 
_reflns.entry_id                                       9CCX 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.3 
_reflns.d_resolution_low                               46.79 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     15953 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.15 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                8.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          13.56 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.30 
_reflns_shell.d_res_low                                     2.38 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             1564 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.913 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               52.84 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9CCX 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.30 
_refine.ls_d_res_low                             46.79 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     15931 
_refine.ls_number_reflns_R_free                  796 
_refine.ls_number_reflns_R_work                  15135 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.16 
_refine.ls_percent_reflns_R_free                 5.00 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1958 
_refine.ls_R_factor_R_free                       0.2289 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1941 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.36 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 27.8939 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2258 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.30 
_refine_hist.d_res_low                        46.79 
_refine_hist.number_atoms_solvent             41 
_refine_hist.number_atoms_total               1987 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        1900 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         46 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0054  ? 2012 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.7086  ? 2744 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0521  ? 294  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0064  ? 353  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 16.2742 ? 311  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.30 2.44  . . 130 2487 99.62 . . . . 0.2701 . . . . . . . . . . . 0.3237 
'X-RAY DIFFRACTION' 2.44 2.63  . . 130 2489 99.36 . . . . 0.2584 . . . . . . . . . . . 0.3518 
'X-RAY DIFFRACTION' 2.63 2.90  . . 133 2510 99.36 . . . . 0.2011 . . . . . . . . . . . 0.2288 
'X-RAY DIFFRACTION' 2.90 3.32  . . 134 2539 99.66 . . . . 0.1929 . . . . . . . . . . . 0.2270 
'X-RAY DIFFRACTION' 3.32 4.18  . . 133 2534 99.40 . . . . 0.1728 . . . . . . . . . . . 0.2163 
'X-RAY DIFFRACTION' 4.18 46.79 . . 136 2576 97.62 . . . . 0.1840 . . . . . . . . . . . 0.1984 
# 
_struct.entry_id                     9CCX 
_struct.title                        'Crystal Structure of the Klebsiella pneumoniae LpxH/JH-LPH-86 complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CCX 
_struct_keywords.text            'LpxH, Inhibitor, Complex, Antibiotic, Lipid A' 
_struct_keywords.pdbx_keywords   ANTIBIOTIC 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A1S0WIC1_KLEPN 
_struct_ref.pdbx_db_accession          A0A1S0WIC1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MATLFIADLHLQTEEPAITAGFLRFLQGEARQADALYILGDLFEAWIGDDDPNPLHQQIASAIKAVVDAGVPCYFIHGNR
DFLVGQRFARQSGMILLAEEERLDLYGREVLIMHGDTLCTDDQGYLAFRAKVHTPWIQRLFLALPLFIRHRIAARMRADS
KAANSSKSMEIMDVNPQAVVDAMERHHVQWLIHGHTHRPAVHELQANGQPAWRVVLGAWHSEGSMVKVTPDDVELIHFPF

;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9CCX 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 240 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             A0A1S0WIC1 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  240 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       240 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9CCX LEU A 241 ? UNP A0A1S0WIC1 ? ? 'expression tag' 241 1  
1 9CCX GLU A 242 ? UNP A0A1S0WIC1 ? ? 'expression tag' 242 2  
1 9CCX GLU A 243 ? UNP A0A1S0WIC1 ? ? 'expression tag' 243 3  
1 9CCX ASN A 244 ? UNP A0A1S0WIC1 ? ? 'expression tag' 244 4  
1 9CCX LEU A 245 ? UNP A0A1S0WIC1 ? ? 'expression tag' 245 5  
1 9CCX TYR A 246 ? UNP A0A1S0WIC1 ? ? 'expression tag' 246 6  
1 9CCX PHE A 247 ? UNP A0A1S0WIC1 ? ? 'expression tag' 247 7  
1 9CCX GLN A 248 ? UNP A0A1S0WIC1 ? ? 'expression tag' 248 8  
1 9CCX SER A 249 ? UNP A0A1S0WIC1 ? ? 'expression tag' 249 9  
1 9CCX HIS A 250 ? UNP A0A1S0WIC1 ? ? 'expression tag' 250 10 
1 9CCX HIS A 251 ? UNP A0A1S0WIC1 ? ? 'expression tag' 251 11 
1 9CCX HIS A 252 ? UNP A0A1S0WIC1 ? ? 'expression tag' 252 12 
1 9CCX HIS A 253 ? UNP A0A1S0WIC1 ? ? 'expression tag' 253 13 
1 9CCX HIS A 254 ? UNP A0A1S0WIC1 ? ? 'expression tag' 254 14 
1 9CCX HIS A 255 ? UNP A0A1S0WIC1 ? ? 'expression tag' 255 15 
1 9CCX HIS A 256 ? UNP A0A1S0WIC1 ? ? 'expression tag' 256 16 
1 9CCX HIS A 257 ? UNP A0A1S0WIC1 ? ? 'expression tag' 257 17 
1 9CCX HIS A 258 ? UNP A0A1S0WIC1 ? ? 'expression tag' 258 18 
1 9CCX HIS A 259 ? UNP A0A1S0WIC1 ? ? 'expression tag' 259 19 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 GLU A 15  ? GLY A 28  ? GLU A 15  GLY A 28  1 ? 14 
HELX_P HELX_P2 AA2 GLU A 29  ? ALA A 33  ? GLU A 29  ALA A 33  5 ? 5  
HELX_P HELX_P3 AA3 ASN A 53  ? ALA A 69  ? ASN A 53  ALA A 69  1 ? 17 
HELX_P HELX_P4 AA4 GLY A 85  ? GLY A 93  ? GLY A 85  GLY A 93  1 ? 9  
HELX_P HELX_P5 AA5 GLY A 115 ? CYS A 119 ? GLY A 115 CYS A 119 5 ? 5  
HELX_P HELX_P6 AA6 ASP A 122 ? HIS A 133 ? ASP A 122 HIS A 133 1 ? 12 
HELX_P HELX_P7 AA7 THR A 134 ? ALA A 143 ? THR A 134 ALA A 143 1 ? 10 
HELX_P HELX_P8 AA8 PRO A 145 ? ALA A 163 ? PRO A 145 ALA A 163 1 ? 19 
HELX_P HELX_P9 AA9 ASN A 175 ? HIS A 186 ? ASN A 175 HIS A 186 1 ? 12 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A ASP 8   OD1 ? ? ? 1_555 D MN  . MN ? ? A ASP 8   A MN  303 1_555 ? ? ? ? ? ? ? 2.083 ? ? 
metalc2  metalc ? ? A HIS 10  NE2 ? ? ? 1_555 D MN  . MN ? ? A HIS 10  A MN  303 1_555 ? ? ? ? ? ? ? 2.298 ? ? 
metalc3  metalc ? ? A ASP 41  OD2 ? ? ? 1_555 D MN  . MN ? ? A ASP 41  A MN  303 1_555 ? ? ? ? ? ? ? 2.223 ? ? 
metalc4  metalc ? ? A ASP 41  OD2 ? ? ? 1_555 E MN  . MN ? ? A ASP 41  A MN  304 1_555 ? ? ? ? ? ? ? 2.312 ? ? 
metalc5  metalc ? ? A ASN 79  OD1 ? ? ? 1_555 E MN  . MN ? ? A ASN 79  A MN  304 1_555 ? ? ? ? ? ? ? 2.004 ? ? 
metalc6  metalc ? ? A HIS 114 NE2 ? ? ? 1_555 E MN  . MN ? ? A HIS 114 A MN  304 1_555 ? ? ? ? ? ? ? 2.311 ? ? 
metalc7  metalc ? ? A HIS 195 ND1 ? ? ? 1_555 E MN  . MN ? ? A HIS 195 A MN  304 1_555 ? ? ? ? ? ? ? 2.409 ? ? 
metalc8  metalc ? ? A HIS 197 NE2 ? ? ? 1_555 D MN  . MN ? ? A HIS 197 A MN  303 1_555 ? ? ? ? ? ? ? 2.306 ? ? 
metalc9  metalc ? ? D MN  .   MN  ? ? ? 1_555 F HOH . O  ? ? A MN  303 A HOH 423 1_555 ? ? ? ? ? ? ? 2.177 ? ? 
metalc10 metalc ? ? E MN  .   MN  ? ? ? 1_555 F HOH . O  ? ? A MN  304 A HOH 423 1_555 ? ? ? ? ? ? ? 2.159 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD1 ? A ASP 8   ? A ASP 8   ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 NE2 ? A HIS 10  ? A HIS 10  ? 1_555 116.4 ? 
2  OD1 ? A ASP 8   ? A ASP 8   ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 OD2 ? A ASP 41  ? A ASP 41  ? 1_555 82.4  ? 
3  NE2 ? A HIS 10  ? A HIS 10  ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 OD2 ? A ASP 41  ? A ASP 41  ? 1_555 92.2  ? 
4  OD1 ? A ASP 8   ? A ASP 8   ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 NE2 ? A HIS 197 ? A HIS 197 ? 1_555 97.2  ? 
5  NE2 ? A HIS 10  ? A HIS 10  ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 NE2 ? A HIS 197 ? A HIS 197 ? 1_555 95.8  ? 
6  OD2 ? A ASP 41  ? A ASP 41  ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 NE2 ? A HIS 197 ? A HIS 197 ? 1_555 171.2 ? 
7  OD1 ? A ASP 8   ? A ASP 8   ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 O   ? F HOH .   ? A HOH 423 ? 1_555 101.8 ? 
8  NE2 ? A HIS 10  ? A HIS 10  ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 O   ? F HOH .   ? A HOH 423 ? 1_555 140.1 ? 
9  OD2 ? A ASP 41  ? A ASP 41  ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 O   ? F HOH .   ? A HOH 423 ? 1_555 81.5  ? 
10 NE2 ? A HIS 197 ? A HIS 197 ? 1_555 MN ? D MN . ? A MN 303 ? 1_555 O   ? F HOH .   ? A HOH 423 ? 1_555 90.1  ? 
11 OD2 ? A ASP 41  ? A ASP 41  ? 1_555 MN ? E MN . ? A MN 304 ? 1_555 OD1 ? A ASN 79  ? A ASN 79  ? 1_555 96.9  ? 
12 OD2 ? A ASP 41  ? A ASP 41  ? 1_555 MN ? E MN . ? A MN 304 ? 1_555 NE2 ? A HIS 114 ? A HIS 114 ? 1_555 99.6  ? 
13 OD1 ? A ASN 79  ? A ASN 79  ? 1_555 MN ? E MN . ? A MN 304 ? 1_555 NE2 ? A HIS 114 ? A HIS 114 ? 1_555 96.8  ? 
14 OD2 ? A ASP 41  ? A ASP 41  ? 1_555 MN ? E MN . ? A MN 304 ? 1_555 ND1 ? A HIS 195 ? A HIS 195 ? 1_555 162.9 ? 
15 OD1 ? A ASN 79  ? A ASN 79  ? 1_555 MN ? E MN . ? A MN 304 ? 1_555 ND1 ? A HIS 195 ? A HIS 195 ? 1_555 93.2  ? 
16 NE2 ? A HIS 114 ? A HIS 114 ? 1_555 MN ? E MN . ? A MN 304 ? 1_555 ND1 ? A HIS 195 ? A HIS 195 ? 1_555 92.8  ? 
17 OD2 ? A ASP 41  ? A ASP 41  ? 1_555 MN ? E MN . ? A MN 304 ? 1_555 O   ? F HOH .   ? A HOH 423 ? 1_555 79.8  ? 
18 OD1 ? A ASN 79  ? A ASN 79  ? 1_555 MN ? E MN . ? A MN 304 ? 1_555 O   ? F HOH .   ? A HOH 423 ? 1_555 120.1 ? 
19 NE2 ? A HIS 114 ? A HIS 114 ? 1_555 MN ? E MN . ? A MN 304 ? 1_555 O   ? F HOH .   ? A HOH 423 ? 1_555 143.0 ? 
20 ND1 ? A HIS 195 ? A HIS 195 ? 1_555 MN ? E MN . ? A MN 304 ? 1_555 O   ? F HOH .   ? A HOH 423 ? 1_555 83.2  ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? parallel      
AA2 3 4 ? parallel      
AA2 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 95  ? LEU A 96  ? ILE A 95  LEU A 96  
AA1 2 CYS A 73  ? PHE A 75  ? CYS A 73  PHE A 75  
AA1 3 ALA A 35  ? ILE A 38  ? ALA A 35  ILE A 38  
AA1 4 THR A 3   ? ILE A 6   ? THR A 3   ILE A 6   
AA1 5 GLY A 223 ? VAL A 228 ? GLY A 223 VAL A 228 
AA1 6 VAL A 233 ? PHE A 238 ? VAL A 233 PHE A 238 
AA2 1 GLU A 100 ? LEU A 105 ? GLU A 100 LEU A 105 
AA2 2 ARG A 108 ? MET A 113 ? ARG A 108 MET A 113 
AA2 3 TRP A 190 ? HIS A 193 ? TRP A 190 HIS A 193 
AA2 4 GLN A 209 ? VAL A 215 ? GLN A 209 VAL A 215 
AA2 5 ALA A 200 ? ALA A 206 ? ALA A 200 ALA A 206 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ILE A 95  ? O ILE A 95  N PHE A 75  ? N PHE A 75  
AA1 2 3 O TYR A 74  ? O TYR A 74  N ILE A 38  ? N ILE A 38  
AA1 3 4 O TYR A 37  ? O TYR A 37  N LEU A 4   ? N LEU A 4   
AA1 4 5 N THR A 3   ? N THR A 3   O VAL A 228 ? O VAL A 228 
AA1 5 6 N MET A 225 ? N MET A 225 O ILE A 236 ? O ILE A 236 
AA2 1 2 N LEU A 103 ? N LEU A 103 O VAL A 110 ? O VAL A 110 
AA2 2 3 N LEU A 111 ? N LEU A 111 O TRP A 190 ? O TRP A 190 
AA2 3 4 N LEU A 191 ? N LEU A 191 O VAL A 214 ? O VAL A 214 
AA2 4 5 O ALA A 211 ? O ALA A 211 N LEU A 204 ? N LEU A 204 
# 
_pdbx_entry_details.entry_id                   9CCX 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LEU A 39  ? ? -92.35  46.65  
2 1 CYS A 119 ? ? -97.53  58.00  
3 1 HIS A 195 ? ? 67.30   -47.38 
4 1 HIS A 220 ? ? -100.04 -71.35 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z          
2 -y,x-y,z+2/3   
3 -x+y,-x,z+1/3  
4 x-y,-y,-z+1/3  
5 -x,-x+y,-z+2/3 
6 y,x,-z         
# 
loop_
_pdbx_refine_tls.id 
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[1][1]_esd 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][2]_esd 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[1][3]_esd 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[2][2]_esd 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.T[2][3]_esd 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[3][3]_esd 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[1][1]_esd 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][2]_esd 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[1][3]_esd 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[2][2]_esd 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.L[2][3]_esd 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[3][3]_esd 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][1]_esd 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][2]_esd 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[1][3]_esd 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][1]_esd 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][2]_esd 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][3]_esd 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][1]_esd 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][2]_esd 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[3][3]_esd 
1 'X-RAY DIFFRACTION' ? refined -36.86439912   -31.1560613845 -0.781545003113 0.380236959721 ? 0.0160383041684  ? 
-0.00248776119651 ? 0.364290154478 ? -0.0299812741335 ? 0.324686522786 ? 2.03717426394 ? -0.806766671804  ? 1.45794397046    ? 
2.59523716583 ? -2.30059532385  ? 4.31662121186  ? 0.0707898463145 ? 0.122321344809   ? -0.0809750649228 ? -0.222884238534 ? 
-0.138197375378 ? -0.0923671663376 ? 0.212749328364   ? 0.20312511355   ? 0.132969504934   ? 
2 'X-RAY DIFFRACTION' ? refined -37.9038005512 -24.6300507698 8.06329678043   0.330963299946 ? 0.0141514967493  ? 0.00914821215585 
? 0.362869238584 ? -0.0302709481361 ? 0.316687541559 ? 1.90271275254 ? -0.220250680347  ? -0.391408347467  ? 2.27034086634 ? 
-0.312058056806 ? 1.41680905933  ? -0.01519428919  ? -0.195155479917  ? 0.122948956268   ? 0.0954076047829 ? 0.0126876888547 ? 
-0.252217467218  ? -0.0190075239278 ? 0.0314048217818 ? -0.0060266621539 ? 
3 'X-RAY DIFFRACTION' ? refined -38.7175291895 -6.18254472309 5.99514959622   0.43202829797  ? 0.0115425764149  ? -0.0269063510274 
? 0.337519650109 ? -0.0954973291322 ? 0.494662067834 ? 2.59232848372 ? -1.11519794995   ? -0.0430417250769 ? 2.57479071122 ? 
0.633471129538  ? 1.86608089401  ? -0.114525344903 ? -0.0676261966363 ? 0.00111606397708 ? -0.065437165753 ? 0.100981215343  ? 
-0.156094812649  ? -0.184781159292  ? 0.0227177387091 ? 0.0188799050891  ? 
4 'X-RAY DIFFRACTION' ? refined -18.4624873403 -18.7866717288 12.5528858315   0.415794611668 ? 0.0242275182324  ? -0.0378968286867 
? 0.582504077173 ? -0.0710572956727 ? 0.641518697247 ? 4.06333564992 ? -3.46459264256   ? 1.58664744402    ? 8.13660526975 ? 
-1.25113543994  ? 0.621155107022 ? 0.0492810546044 ? -0.212513003555  ? 0.808666329406   ? 0.460525616144  ? -0.38882123179  ? 
-1.12536285992   ? -0.266890993135  ? 0.0869455048061 ? 0.328251243132   ? 
5 'X-RAY DIFFRACTION' ? refined -21.3834565416 -29.0656081857 7.49858573761   0.306398618678 ? 0.00653712493153 ? -0.03931195614 ? 
0.317046828573 ? -0.0241261530478 ? 0.379348354998 ? 2.84004480486 ? -0.0502520250135 ? -0.751652780802  ? 2.6850386433  ? 
1.23439680275   ? 2.34192127306  ? 0.0248005201618 ? -0.0559467311911 ? 0.197589683482   ? 0.128677539394  ? 0.121355804246  ? 
-0.328805694369  ? 0.00890552231097 ? 0.102336312659  ? -0.153455214448  ? 
6 'X-RAY DIFFRACTION' ? refined -26.7108647778 -40.0090825946 -12.033973967   0.496202811765 ? 0.0312868317732  ? 
-0.00648838371998 ? 0.518745323502 ? 0.0449687863802  ? 0.574357120194 ? 1.24885053737 ? -0.154249395535  ? 0.454792394491   ? 
1.4714721951  ? 1.18313255167   ? 3.51067286821  ? 0.131217906183  ? 0.410092914441   ? 0.192246516195   ? -0.472248142979 ? 
-0.208369880311 ? 0.165944020702   ? 0.238452894285   ? 0.0680624379777 ? 0.0467896441543  ? 
# 
loop_
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_PDB_ins_code 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_PDB_ins_code 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
1 'X-RAY DIFFRACTION' 1 A 1   A 2   ? A 37  A 38  ? ? 
;chain 'A' and (resid 2 through 38 )
;
2 'X-RAY DIFFRACTION' 2 A 38  A 39  ? A 121 A 122 ? ? 
;chain 'A' and (resid 39 through 122 )
;
3 'X-RAY DIFFRACTION' 3 A 122 A 123 ? A 161 A 162 ? ? 
;chain 'A' and (resid 123 through 162 )
;
4 'X-RAY DIFFRACTION' 4 A 162 A 163 ? A 177 A 185 ? ? 
;chain 'A' and (resid 163 through 185 )
;
5 'X-RAY DIFFRACTION' 5 A 178 A 186 ? A 220 A 228 ? ? 
;chain 'A' and (resid 186 through 228 )
;
6 'X-RAY DIFFRACTION' 6 A 221 A 229 ? A 244 A 252 ? ? 
;chain 'A' and (resid 229 through 252 )
;
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A SER 165 ? A SER 165 
3  1 Y 1 A SER 166 ? A SER 166 
4  1 Y 1 A LYS 167 ? A LYS 167 
5  1 Y 1 A SER 168 ? A SER 168 
6  1 Y 1 A MET 169 ? A MET 169 
7  1 Y 1 A GLU 170 ? A GLU 170 
8  1 Y 1 A ILE 171 ? A ILE 171 
9  1 Y 1 A HIS 253 ? A HIS 253 
10 1 Y 1 A HIS 254 ? A HIS 254 
11 1 Y 1 A HIS 255 ? A HIS 255 
12 1 Y 1 A HIS 256 ? A HIS 256 
13 1 Y 1 A HIS 257 ? A HIS 257 
14 1 Y 1 A HIS 258 ? A HIS 258 
15 1 Y 1 A HIS 259 ? A HIS 259 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1AVZ C13  C  Y N 1   
A1AVZ C15  C  Y N 2   
A1AVZ C17  C  Y N 3   
A1AVZ C20  C  N N 4   
A1AVZ C22  C  N N 5   
A1AVZ C24  C  N N 6   
A1AVZ C26  C  Y N 7   
A1AVZ C28  C  N N 8   
A1AVZ C01  C  Y N 9   
A1AVZ C03  C  Y N 10  
A1AVZ C05  C  N N 11  
A1AVZ C06  C  N N 12  
A1AVZ C08  C  N N 13  
A1AVZ C09  C  N N 14  
A1AVZ C14  C  Y N 15  
A1AVZ C16  C  Y N 16  
A1AVZ C18  C  Y N 17  
A1AVZ C19  C  N N 18  
A1AVZ C25  C  Y N 19  
A1AVZ C27  C  Y N 20  
A1AVZ F29  F  N N 21  
A1AVZ F30  F  N N 22  
A1AVZ F31  F  N N 23  
A1AVZ N02  N  Y N 24  
A1AVZ N04  N  N N 25  
A1AVZ N07  N  N N 26  
A1AVZ N21  N  N N 27  
A1AVZ O11  O  N N 28  
A1AVZ O12  O  N N 29  
A1AVZ O23  O  N N 30  
A1AVZ S10  S  N N 31  
A1AVZ H151 H  N N 32  
A1AVZ H201 H  N N 33  
A1AVZ H202 H  N N 34  
A1AVZ H241 H  N N 35  
A1AVZ H242 H  N N 36  
A1AVZ H243 H  N N 37  
A1AVZ H011 H  N N 38  
A1AVZ H051 H  N N 39  
A1AVZ H052 H  N N 40  
A1AVZ H061 H  N N 41  
A1AVZ H062 H  N N 42  
A1AVZ H082 H  N N 43  
A1AVZ H081 H  N N 44  
A1AVZ H091 H  N N 45  
A1AVZ H092 H  N N 46  
A1AVZ H141 H  N N 47  
A1AVZ H181 H  N N 48  
A1AVZ H192 H  N N 49  
A1AVZ H191 H  N N 50  
A1AVZ H251 H  N N 51  
A1AVZ H271 H  N N 52  
ALA   N    N  N N 53  
ALA   CA   C  N S 54  
ALA   C    C  N N 55  
ALA   O    O  N N 56  
ALA   CB   C  N N 57  
ALA   OXT  O  N N 58  
ALA   H    H  N N 59  
ALA   H2   H  N N 60  
ALA   HA   H  N N 61  
ALA   HB1  H  N N 62  
ALA   HB2  H  N N 63  
ALA   HB3  H  N N 64  
ALA   HXT  H  N N 65  
ARG   N    N  N N 66  
ARG   CA   C  N S 67  
ARG   C    C  N N 68  
ARG   O    O  N N 69  
ARG   CB   C  N N 70  
ARG   CG   C  N N 71  
ARG   CD   C  N N 72  
ARG   NE   N  N N 73  
ARG   CZ   C  N N 74  
ARG   NH1  N  N N 75  
ARG   NH2  N  N N 76  
ARG   OXT  O  N N 77  
ARG   H    H  N N 78  
ARG   H2   H  N N 79  
ARG   HA   H  N N 80  
ARG   HB2  H  N N 81  
ARG   HB3  H  N N 82  
ARG   HG2  H  N N 83  
ARG   HG3  H  N N 84  
ARG   HD2  H  N N 85  
ARG   HD3  H  N N 86  
ARG   HE   H  N N 87  
ARG   HH11 H  N N 88  
ARG   HH12 H  N N 89  
ARG   HH21 H  N N 90  
ARG   HH22 H  N N 91  
ARG   HXT  H  N N 92  
ASN   N    N  N N 93  
ASN   CA   C  N S 94  
ASN   C    C  N N 95  
ASN   O    O  N N 96  
ASN   CB   C  N N 97  
ASN   CG   C  N N 98  
ASN   OD1  O  N N 99  
ASN   ND2  N  N N 100 
ASN   OXT  O  N N 101 
ASN   H    H  N N 102 
ASN   H2   H  N N 103 
ASN   HA   H  N N 104 
ASN   HB2  H  N N 105 
ASN   HB3  H  N N 106 
ASN   HD21 H  N N 107 
ASN   HD22 H  N N 108 
ASN   HXT  H  N N 109 
ASP   N    N  N N 110 
ASP   CA   C  N S 111 
ASP   C    C  N N 112 
ASP   O    O  N N 113 
ASP   CB   C  N N 114 
ASP   CG   C  N N 115 
ASP   OD1  O  N N 116 
ASP   OD2  O  N N 117 
ASP   OXT  O  N N 118 
ASP   H    H  N N 119 
ASP   H2   H  N N 120 
ASP   HA   H  N N 121 
ASP   HB2  H  N N 122 
ASP   HB3  H  N N 123 
ASP   HD2  H  N N 124 
ASP   HXT  H  N N 125 
CYS   N    N  N N 126 
CYS   CA   C  N R 127 
CYS   C    C  N N 128 
CYS   O    O  N N 129 
CYS   CB   C  N N 130 
CYS   SG   S  N N 131 
CYS   OXT  O  N N 132 
CYS   H    H  N N 133 
CYS   H2   H  N N 134 
CYS   HA   H  N N 135 
CYS   HB2  H  N N 136 
CYS   HB3  H  N N 137 
CYS   HG   H  N N 138 
CYS   HXT  H  N N 139 
GLN   N    N  N N 140 
GLN   CA   C  N S 141 
GLN   C    C  N N 142 
GLN   O    O  N N 143 
GLN   CB   C  N N 144 
GLN   CG   C  N N 145 
GLN   CD   C  N N 146 
GLN   OE1  O  N N 147 
GLN   NE2  N  N N 148 
GLN   OXT  O  N N 149 
GLN   H    H  N N 150 
GLN   H2   H  N N 151 
GLN   HA   H  N N 152 
GLN   HB2  H  N N 153 
GLN   HB3  H  N N 154 
GLN   HG2  H  N N 155 
GLN   HG3  H  N N 156 
GLN   HE21 H  N N 157 
GLN   HE22 H  N N 158 
GLN   HXT  H  N N 159 
GLU   N    N  N N 160 
GLU   CA   C  N S 161 
GLU   C    C  N N 162 
GLU   O    O  N N 163 
GLU   CB   C  N N 164 
GLU   CG   C  N N 165 
GLU   CD   C  N N 166 
GLU   OE1  O  N N 167 
GLU   OE2  O  N N 168 
GLU   OXT  O  N N 169 
GLU   H    H  N N 170 
GLU   H2   H  N N 171 
GLU   HA   H  N N 172 
GLU   HB2  H  N N 173 
GLU   HB3  H  N N 174 
GLU   HG2  H  N N 175 
GLU   HG3  H  N N 176 
GLU   HE2  H  N N 177 
GLU   HXT  H  N N 178 
GLY   N    N  N N 179 
GLY   CA   C  N N 180 
GLY   C    C  N N 181 
GLY   O    O  N N 182 
GLY   OXT  O  N N 183 
GLY   H    H  N N 184 
GLY   H2   H  N N 185 
GLY   HA2  H  N N 186 
GLY   HA3  H  N N 187 
GLY   HXT  H  N N 188 
HIS   N    N  N N 189 
HIS   CA   C  N S 190 
HIS   C    C  N N 191 
HIS   O    O  N N 192 
HIS   CB   C  N N 193 
HIS   CG   C  Y N 194 
HIS   ND1  N  Y N 195 
HIS   CD2  C  Y N 196 
HIS   CE1  C  Y N 197 
HIS   NE2  N  Y N 198 
HIS   OXT  O  N N 199 
HIS   H    H  N N 200 
HIS   H2   H  N N 201 
HIS   HA   H  N N 202 
HIS   HB2  H  N N 203 
HIS   HB3  H  N N 204 
HIS   HD1  H  N N 205 
HIS   HD2  H  N N 206 
HIS   HE1  H  N N 207 
HIS   HE2  H  N N 208 
HIS   HXT  H  N N 209 
HOH   O    O  N N 210 
HOH   H1   H  N N 211 
HOH   H2   H  N N 212 
ILE   N    N  N N 213 
ILE   CA   C  N S 214 
ILE   C    C  N N 215 
ILE   O    O  N N 216 
ILE   CB   C  N S 217 
ILE   CG1  C  N N 218 
ILE   CG2  C  N N 219 
ILE   CD1  C  N N 220 
ILE   OXT  O  N N 221 
ILE   H    H  N N 222 
ILE   H2   H  N N 223 
ILE   HA   H  N N 224 
ILE   HB   H  N N 225 
ILE   HG12 H  N N 226 
ILE   HG13 H  N N 227 
ILE   HG21 H  N N 228 
ILE   HG22 H  N N 229 
ILE   HG23 H  N N 230 
ILE   HD11 H  N N 231 
ILE   HD12 H  N N 232 
ILE   HD13 H  N N 233 
ILE   HXT  H  N N 234 
LEU   N    N  N N 235 
LEU   CA   C  N S 236 
LEU   C    C  N N 237 
LEU   O    O  N N 238 
LEU   CB   C  N N 239 
LEU   CG   C  N N 240 
LEU   CD1  C  N N 241 
LEU   CD2  C  N N 242 
LEU   OXT  O  N N 243 
LEU   H    H  N N 244 
LEU   H2   H  N N 245 
LEU   HA   H  N N 246 
LEU   HB2  H  N N 247 
LEU   HB3  H  N N 248 
LEU   HG   H  N N 249 
LEU   HD11 H  N N 250 
LEU   HD12 H  N N 251 
LEU   HD13 H  N N 252 
LEU   HD21 H  N N 253 
LEU   HD22 H  N N 254 
LEU   HD23 H  N N 255 
LEU   HXT  H  N N 256 
LYS   N    N  N N 257 
LYS   CA   C  N S 258 
LYS   C    C  N N 259 
LYS   O    O  N N 260 
LYS   CB   C  N N 261 
LYS   CG   C  N N 262 
LYS   CD   C  N N 263 
LYS   CE   C  N N 264 
LYS   NZ   N  N N 265 
LYS   OXT  O  N N 266 
LYS   H    H  N N 267 
LYS   H2   H  N N 268 
LYS   HA   H  N N 269 
LYS   HB2  H  N N 270 
LYS   HB3  H  N N 271 
LYS   HG2  H  N N 272 
LYS   HG3  H  N N 273 
LYS   HD2  H  N N 274 
LYS   HD3  H  N N 275 
LYS   HE2  H  N N 276 
LYS   HE3  H  N N 277 
LYS   HZ1  H  N N 278 
LYS   HZ2  H  N N 279 
LYS   HZ3  H  N N 280 
LYS   HXT  H  N N 281 
MET   N    N  N N 282 
MET   CA   C  N S 283 
MET   C    C  N N 284 
MET   O    O  N N 285 
MET   CB   C  N N 286 
MET   CG   C  N N 287 
MET   SD   S  N N 288 
MET   CE   C  N N 289 
MET   OXT  O  N N 290 
MET   H    H  N N 291 
MET   H2   H  N N 292 
MET   HA   H  N N 293 
MET   HB2  H  N N 294 
MET   HB3  H  N N 295 
MET   HG2  H  N N 296 
MET   HG3  H  N N 297 
MET   HE1  H  N N 298 
MET   HE2  H  N N 299 
MET   HE3  H  N N 300 
MET   HXT  H  N N 301 
MN    MN   MN N N 302 
PG4   O1   O  N N 303 
PG4   C1   C  N N 304 
PG4   C2   C  N N 305 
PG4   O2   O  N N 306 
PG4   C3   C  N N 307 
PG4   C4   C  N N 308 
PG4   O3   O  N N 309 
PG4   C5   C  N N 310 
PG4   C6   C  N N 311 
PG4   O4   O  N N 312 
PG4   C7   C  N N 313 
PG4   C8   C  N N 314 
PG4   O5   O  N N 315 
PG4   HO1  H  N N 316 
PG4   H11  H  N N 317 
PG4   H12  H  N N 318 
PG4   H21  H  N N 319 
PG4   H22  H  N N 320 
PG4   H31  H  N N 321 
PG4   H32  H  N N 322 
PG4   H41  H  N N 323 
PG4   H42  H  N N 324 
PG4   H51  H  N N 325 
PG4   H52  H  N N 326 
PG4   H61  H  N N 327 
PG4   H62  H  N N 328 
PG4   H71  H  N N 329 
PG4   H72  H  N N 330 
PG4   H81  H  N N 331 
PG4   H82  H  N N 332 
PG4   HO5  H  N N 333 
PHE   N    N  N N 334 
PHE   CA   C  N S 335 
PHE   C    C  N N 336 
PHE   O    O  N N 337 
PHE   CB   C  N N 338 
PHE   CG   C  Y N 339 
PHE   CD1  C  Y N 340 
PHE   CD2  C  Y N 341 
PHE   CE1  C  Y N 342 
PHE   CE2  C  Y N 343 
PHE   CZ   C  Y N 344 
PHE   OXT  O  N N 345 
PHE   H    H  N N 346 
PHE   H2   H  N N 347 
PHE   HA   H  N N 348 
PHE   HB2  H  N N 349 
PHE   HB3  H  N N 350 
PHE   HD1  H  N N 351 
PHE   HD2  H  N N 352 
PHE   HE1  H  N N 353 
PHE   HE2  H  N N 354 
PHE   HZ   H  N N 355 
PHE   HXT  H  N N 356 
PRO   N    N  N N 357 
PRO   CA   C  N S 358 
PRO   C    C  N N 359 
PRO   O    O  N N 360 
PRO   CB   C  N N 361 
PRO   CG   C  N N 362 
PRO   CD   C  N N 363 
PRO   OXT  O  N N 364 
PRO   H    H  N N 365 
PRO   HA   H  N N 366 
PRO   HB2  H  N N 367 
PRO   HB3  H  N N 368 
PRO   HG2  H  N N 369 
PRO   HG3  H  N N 370 
PRO   HD2  H  N N 371 
PRO   HD3  H  N N 372 
PRO   HXT  H  N N 373 
SER   N    N  N N 374 
SER   CA   C  N S 375 
SER   C    C  N N 376 
SER   O    O  N N 377 
SER   CB   C  N N 378 
SER   OG   O  N N 379 
SER   OXT  O  N N 380 
SER   H    H  N N 381 
SER   H2   H  N N 382 
SER   HA   H  N N 383 
SER   HB2  H  N N 384 
SER   HB3  H  N N 385 
SER   HG   H  N N 386 
SER   HXT  H  N N 387 
THR   N    N  N N 388 
THR   CA   C  N S 389 
THR   C    C  N N 390 
THR   O    O  N N 391 
THR   CB   C  N R 392 
THR   OG1  O  N N 393 
THR   CG2  C  N N 394 
THR   OXT  O  N N 395 
THR   H    H  N N 396 
THR   H2   H  N N 397 
THR   HA   H  N N 398 
THR   HB   H  N N 399 
THR   HG1  H  N N 400 
THR   HG21 H  N N 401 
THR   HG22 H  N N 402 
THR   HG23 H  N N 403 
THR   HXT  H  N N 404 
TRP   N    N  N N 405 
TRP   CA   C  N S 406 
TRP   C    C  N N 407 
TRP   O    O  N N 408 
TRP   CB   C  N N 409 
TRP   CG   C  Y N 410 
TRP   CD1  C  Y N 411 
TRP   CD2  C  Y N 412 
TRP   NE1  N  Y N 413 
TRP   CE2  C  Y N 414 
TRP   CE3  C  Y N 415 
TRP   CZ2  C  Y N 416 
TRP   CZ3  C  Y N 417 
TRP   CH2  C  Y N 418 
TRP   OXT  O  N N 419 
TRP   H    H  N N 420 
TRP   H2   H  N N 421 
TRP   HA   H  N N 422 
TRP   HB2  H  N N 423 
TRP   HB3  H  N N 424 
TRP   HD1  H  N N 425 
TRP   HE1  H  N N 426 
TRP   HE3  H  N N 427 
TRP   HZ2  H  N N 428 
TRP   HZ3  H  N N 429 
TRP   HH2  H  N N 430 
TRP   HXT  H  N N 431 
TYR   N    N  N N 432 
TYR   CA   C  N S 433 
TYR   C    C  N N 434 
TYR   O    O  N N 435 
TYR   CB   C  N N 436 
TYR   CG   C  Y N 437 
TYR   CD1  C  Y N 438 
TYR   CD2  C  Y N 439 
TYR   CE1  C  Y N 440 
TYR   CE2  C  Y N 441 
TYR   CZ   C  Y N 442 
TYR   OH   O  N N 443 
TYR   OXT  O  N N 444 
TYR   H    H  N N 445 
TYR   H2   H  N N 446 
TYR   HA   H  N N 447 
TYR   HB2  H  N N 448 
TYR   HB3  H  N N 449 
TYR   HD1  H  N N 450 
TYR   HD2  H  N N 451 
TYR   HE1  H  N N 452 
TYR   HE2  H  N N 453 
TYR   HH   H  N N 454 
TYR   HXT  H  N N 455 
VAL   N    N  N N 456 
VAL   CA   C  N S 457 
VAL   C    C  N N 458 
VAL   O    O  N N 459 
VAL   CB   C  N N 460 
VAL   CG1  C  N N 461 
VAL   CG2  C  N N 462 
VAL   OXT  O  N N 463 
VAL   H    H  N N 464 
VAL   H2   H  N N 465 
VAL   HA   H  N N 466 
VAL   HB   H  N N 467 
VAL   HG11 H  N N 468 
VAL   HG12 H  N N 469 
VAL   HG13 H  N N 470 
VAL   HG21 H  N N 471 
VAL   HG22 H  N N 472 
VAL   HG23 H  N N 473 
VAL   HXT  H  N N 474 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1AVZ N02 C01  doub Y N 1   
A1AVZ C03 N02  sing Y N 2   
A1AVZ C05 N04  sing N N 3   
A1AVZ C06 C05  sing N N 4   
A1AVZ N07 C06  sing N N 5   
A1AVZ C09 C08  sing N N 6   
A1AVZ C08 N07  sing N N 7   
A1AVZ S10 N07  sing N N 8   
A1AVZ O11 S10  doub N N 9   
A1AVZ O12 S10  doub N N 10  
A1AVZ C13 S10  sing N N 11  
A1AVZ C14 C13  doub Y N 12  
A1AVZ C15 C14  sing Y N 13  
A1AVZ C16 C15  doub Y N 14  
A1AVZ C17 C16  sing Y N 15  
A1AVZ C18 C17  doub Y N 16  
A1AVZ C19 C17  sing N N 17  
A1AVZ C20 C19  sing N N 18  
A1AVZ N21 C20  sing N N 19  
A1AVZ C22 N21  sing N N 20  
A1AVZ O23 C22  doub N N 21  
A1AVZ C24 C22  sing N N 22  
A1AVZ N04 C03  sing N N 23  
A1AVZ C25 C03  doub Y N 24  
A1AVZ C26 C25  sing Y N 25  
A1AVZ C27 C26  doub Y N 26  
A1AVZ C28 C26  sing N N 27  
A1AVZ F29 C28  sing N N 28  
A1AVZ F30 C28  sing N N 29  
A1AVZ F31 C28  sing N N 30  
A1AVZ C01 C27  sing Y N 31  
A1AVZ N04 C09  sing N N 32  
A1AVZ C13 C18  sing Y N 33  
A1AVZ C16 N21  sing N N 34  
A1AVZ C15 H151 sing N N 35  
A1AVZ C20 H201 sing N N 36  
A1AVZ C20 H202 sing N N 37  
A1AVZ C24 H241 sing N N 38  
A1AVZ C24 H242 sing N N 39  
A1AVZ C24 H243 sing N N 40  
A1AVZ C01 H011 sing N N 41  
A1AVZ C05 H051 sing N N 42  
A1AVZ C05 H052 sing N N 43  
A1AVZ C06 H061 sing N N 44  
A1AVZ C06 H062 sing N N 45  
A1AVZ C08 H082 sing N N 46  
A1AVZ C08 H081 sing N N 47  
A1AVZ C09 H091 sing N N 48  
A1AVZ C09 H092 sing N N 49  
A1AVZ C14 H141 sing N N 50  
A1AVZ C18 H181 sing N N 51  
A1AVZ C19 H192 sing N N 52  
A1AVZ C19 H191 sing N N 53  
A1AVZ C25 H251 sing N N 54  
A1AVZ C27 H271 sing N N 55  
ALA   N   CA   sing N N 56  
ALA   N   H    sing N N 57  
ALA   N   H2   sing N N 58  
ALA   CA  C    sing N N 59  
ALA   CA  CB   sing N N 60  
ALA   CA  HA   sing N N 61  
ALA   C   O    doub N N 62  
ALA   C   OXT  sing N N 63  
ALA   CB  HB1  sing N N 64  
ALA   CB  HB2  sing N N 65  
ALA   CB  HB3  sing N N 66  
ALA   OXT HXT  sing N N 67  
ARG   N   CA   sing N N 68  
ARG   N   H    sing N N 69  
ARG   N   H2   sing N N 70  
ARG   CA  C    sing N N 71  
ARG   CA  CB   sing N N 72  
ARG   CA  HA   sing N N 73  
ARG   C   O    doub N N 74  
ARG   C   OXT  sing N N 75  
ARG   CB  CG   sing N N 76  
ARG   CB  HB2  sing N N 77  
ARG   CB  HB3  sing N N 78  
ARG   CG  CD   sing N N 79  
ARG   CG  HG2  sing N N 80  
ARG   CG  HG3  sing N N 81  
ARG   CD  NE   sing N N 82  
ARG   CD  HD2  sing N N 83  
ARG   CD  HD3  sing N N 84  
ARG   NE  CZ   sing N N 85  
ARG   NE  HE   sing N N 86  
ARG   CZ  NH1  sing N N 87  
ARG   CZ  NH2  doub N N 88  
ARG   NH1 HH11 sing N N 89  
ARG   NH1 HH12 sing N N 90  
ARG   NH2 HH21 sing N N 91  
ARG   NH2 HH22 sing N N 92  
ARG   OXT HXT  sing N N 93  
ASN   N   CA   sing N N 94  
ASN   N   H    sing N N 95  
ASN   N   H2   sing N N 96  
ASN   CA  C    sing N N 97  
ASN   CA  CB   sing N N 98  
ASN   CA  HA   sing N N 99  
ASN   C   O    doub N N 100 
ASN   C   OXT  sing N N 101 
ASN   CB  CG   sing N N 102 
ASN   CB  HB2  sing N N 103 
ASN   CB  HB3  sing N N 104 
ASN   CG  OD1  doub N N 105 
ASN   CG  ND2  sing N N 106 
ASN   ND2 HD21 sing N N 107 
ASN   ND2 HD22 sing N N 108 
ASN   OXT HXT  sing N N 109 
ASP   N   CA   sing N N 110 
ASP   N   H    sing N N 111 
ASP   N   H2   sing N N 112 
ASP   CA  C    sing N N 113 
ASP   CA  CB   sing N N 114 
ASP   CA  HA   sing N N 115 
ASP   C   O    doub N N 116 
ASP   C   OXT  sing N N 117 
ASP   CB  CG   sing N N 118 
ASP   CB  HB2  sing N N 119 
ASP   CB  HB3  sing N N 120 
ASP   CG  OD1  doub N N 121 
ASP   CG  OD2  sing N N 122 
ASP   OD2 HD2  sing N N 123 
ASP   OXT HXT  sing N N 124 
CYS   N   CA   sing N N 125 
CYS   N   H    sing N N 126 
CYS   N   H2   sing N N 127 
CYS   CA  C    sing N N 128 
CYS   CA  CB   sing N N 129 
CYS   CA  HA   sing N N 130 
CYS   C   O    doub N N 131 
CYS   C   OXT  sing N N 132 
CYS   CB  SG   sing N N 133 
CYS   CB  HB2  sing N N 134 
CYS   CB  HB3  sing N N 135 
CYS   SG  HG   sing N N 136 
CYS   OXT HXT  sing N N 137 
GLN   N   CA   sing N N 138 
GLN   N   H    sing N N 139 
GLN   N   H2   sing N N 140 
GLN   CA  C    sing N N 141 
GLN   CA  CB   sing N N 142 
GLN   CA  HA   sing N N 143 
GLN   C   O    doub N N 144 
GLN   C   OXT  sing N N 145 
GLN   CB  CG   sing N N 146 
GLN   CB  HB2  sing N N 147 
GLN   CB  HB3  sing N N 148 
GLN   CG  CD   sing N N 149 
GLN   CG  HG2  sing N N 150 
GLN   CG  HG3  sing N N 151 
GLN   CD  OE1  doub N N 152 
GLN   CD  NE2  sing N N 153 
GLN   NE2 HE21 sing N N 154 
GLN   NE2 HE22 sing N N 155 
GLN   OXT HXT  sing N N 156 
GLU   N   CA   sing N N 157 
GLU   N   H    sing N N 158 
GLU   N   H2   sing N N 159 
GLU   CA  C    sing N N 160 
GLU   CA  CB   sing N N 161 
GLU   CA  HA   sing N N 162 
GLU   C   O    doub N N 163 
GLU   C   OXT  sing N N 164 
GLU   CB  CG   sing N N 165 
GLU   CB  HB2  sing N N 166 
GLU   CB  HB3  sing N N 167 
GLU   CG  CD   sing N N 168 
GLU   CG  HG2  sing N N 169 
GLU   CG  HG3  sing N N 170 
GLU   CD  OE1  doub N N 171 
GLU   CD  OE2  sing N N 172 
GLU   OE2 HE2  sing N N 173 
GLU   OXT HXT  sing N N 174 
GLY   N   CA   sing N N 175 
GLY   N   H    sing N N 176 
GLY   N   H2   sing N N 177 
GLY   CA  C    sing N N 178 
GLY   CA  HA2  sing N N 179 
GLY   CA  HA3  sing N N 180 
GLY   C   O    doub N N 181 
GLY   C   OXT  sing N N 182 
GLY   OXT HXT  sing N N 183 
HIS   N   CA   sing N N 184 
HIS   N   H    sing N N 185 
HIS   N   H2   sing N N 186 
HIS   CA  C    sing N N 187 
HIS   CA  CB   sing N N 188 
HIS   CA  HA   sing N N 189 
HIS   C   O    doub N N 190 
HIS   C   OXT  sing N N 191 
HIS   CB  CG   sing N N 192 
HIS   CB  HB2  sing N N 193 
HIS   CB  HB3  sing N N 194 
HIS   CG  ND1  sing Y N 195 
HIS   CG  CD2  doub Y N 196 
HIS   ND1 CE1  doub Y N 197 
HIS   ND1 HD1  sing N N 198 
HIS   CD2 NE2  sing Y N 199 
HIS   CD2 HD2  sing N N 200 
HIS   CE1 NE2  sing Y N 201 
HIS   CE1 HE1  sing N N 202 
HIS   NE2 HE2  sing N N 203 
HIS   OXT HXT  sing N N 204 
HOH   O   H1   sing N N 205 
HOH   O   H2   sing N N 206 
ILE   N   CA   sing N N 207 
ILE   N   H    sing N N 208 
ILE   N   H2   sing N N 209 
ILE   CA  C    sing N N 210 
ILE   CA  CB   sing N N 211 
ILE   CA  HA   sing N N 212 
ILE   C   O    doub N N 213 
ILE   C   OXT  sing N N 214 
ILE   CB  CG1  sing N N 215 
ILE   CB  CG2  sing N N 216 
ILE   CB  HB   sing N N 217 
ILE   CG1 CD1  sing N N 218 
ILE   CG1 HG12 sing N N 219 
ILE   CG1 HG13 sing N N 220 
ILE   CG2 HG21 sing N N 221 
ILE   CG2 HG22 sing N N 222 
ILE   CG2 HG23 sing N N 223 
ILE   CD1 HD11 sing N N 224 
ILE   CD1 HD12 sing N N 225 
ILE   CD1 HD13 sing N N 226 
ILE   OXT HXT  sing N N 227 
LEU   N   CA   sing N N 228 
LEU   N   H    sing N N 229 
LEU   N   H2   sing N N 230 
LEU   CA  C    sing N N 231 
LEU   CA  CB   sing N N 232 
LEU   CA  HA   sing N N 233 
LEU   C   O    doub N N 234 
LEU   C   OXT  sing N N 235 
LEU   CB  CG   sing N N 236 
LEU   CB  HB2  sing N N 237 
LEU   CB  HB3  sing N N 238 
LEU   CG  CD1  sing N N 239 
LEU   CG  CD2  sing N N 240 
LEU   CG  HG   sing N N 241 
LEU   CD1 HD11 sing N N 242 
LEU   CD1 HD12 sing N N 243 
LEU   CD1 HD13 sing N N 244 
LEU   CD2 HD21 sing N N 245 
LEU   CD2 HD22 sing N N 246 
LEU   CD2 HD23 sing N N 247 
LEU   OXT HXT  sing N N 248 
LYS   N   CA   sing N N 249 
LYS   N   H    sing N N 250 
LYS   N   H2   sing N N 251 
LYS   CA  C    sing N N 252 
LYS   CA  CB   sing N N 253 
LYS   CA  HA   sing N N 254 
LYS   C   O    doub N N 255 
LYS   C   OXT  sing N N 256 
LYS   CB  CG   sing N N 257 
LYS   CB  HB2  sing N N 258 
LYS   CB  HB3  sing N N 259 
LYS   CG  CD   sing N N 260 
LYS   CG  HG2  sing N N 261 
LYS   CG  HG3  sing N N 262 
LYS   CD  CE   sing N N 263 
LYS   CD  HD2  sing N N 264 
LYS   CD  HD3  sing N N 265 
LYS   CE  NZ   sing N N 266 
LYS   CE  HE2  sing N N 267 
LYS   CE  HE3  sing N N 268 
LYS   NZ  HZ1  sing N N 269 
LYS   NZ  HZ2  sing N N 270 
LYS   NZ  HZ3  sing N N 271 
LYS   OXT HXT  sing N N 272 
MET   N   CA   sing N N 273 
MET   N   H    sing N N 274 
MET   N   H2   sing N N 275 
MET   CA  C    sing N N 276 
MET   CA  CB   sing N N 277 
MET   CA  HA   sing N N 278 
MET   C   O    doub N N 279 
MET   C   OXT  sing N N 280 
MET   CB  CG   sing N N 281 
MET   CB  HB2  sing N N 282 
MET   CB  HB3  sing N N 283 
MET   CG  SD   sing N N 284 
MET   CG  HG2  sing N N 285 
MET   CG  HG3  sing N N 286 
MET   SD  CE   sing N N 287 
MET   CE  HE1  sing N N 288 
MET   CE  HE2  sing N N 289 
MET   CE  HE3  sing N N 290 
MET   OXT HXT  sing N N 291 
PG4   O1  C1   sing N N 292 
PG4   O1  HO1  sing N N 293 
PG4   C1  C2   sing N N 294 
PG4   C1  H11  sing N N 295 
PG4   C1  H12  sing N N 296 
PG4   C2  O2   sing N N 297 
PG4   C2  H21  sing N N 298 
PG4   C2  H22  sing N N 299 
PG4   O2  C3   sing N N 300 
PG4   C3  C4   sing N N 301 
PG4   C3  H31  sing N N 302 
PG4   C3  H32  sing N N 303 
PG4   C4  O3   sing N N 304 
PG4   C4  H41  sing N N 305 
PG4   C4  H42  sing N N 306 
PG4   O3  C5   sing N N 307 
PG4   C5  C6   sing N N 308 
PG4   C5  H51  sing N N 309 
PG4   C5  H52  sing N N 310 
PG4   C6  O4   sing N N 311 
PG4   C6  H61  sing N N 312 
PG4   C6  H62  sing N N 313 
PG4   O4  C7   sing N N 314 
PG4   C7  C8   sing N N 315 
PG4   C7  H71  sing N N 316 
PG4   C7  H72  sing N N 317 
PG4   C8  O5   sing N N 318 
PG4   C8  H81  sing N N 319 
PG4   C8  H82  sing N N 320 
PG4   O5  HO5  sing N N 321 
PHE   N   CA   sing N N 322 
PHE   N   H    sing N N 323 
PHE   N   H2   sing N N 324 
PHE   CA  C    sing N N 325 
PHE   CA  CB   sing N N 326 
PHE   CA  HA   sing N N 327 
PHE   C   O    doub N N 328 
PHE   C   OXT  sing N N 329 
PHE   CB  CG   sing N N 330 
PHE   CB  HB2  sing N N 331 
PHE   CB  HB3  sing N N 332 
PHE   CG  CD1  doub Y N 333 
PHE   CG  CD2  sing Y N 334 
PHE   CD1 CE1  sing Y N 335 
PHE   CD1 HD1  sing N N 336 
PHE   CD2 CE2  doub Y N 337 
PHE   CD2 HD2  sing N N 338 
PHE   CE1 CZ   doub Y N 339 
PHE   CE1 HE1  sing N N 340 
PHE   CE2 CZ   sing Y N 341 
PHE   CE2 HE2  sing N N 342 
PHE   CZ  HZ   sing N N 343 
PHE   OXT HXT  sing N N 344 
PRO   N   CA   sing N N 345 
PRO   N   CD   sing N N 346 
PRO   N   H    sing N N 347 
PRO   CA  C    sing N N 348 
PRO   CA  CB   sing N N 349 
PRO   CA  HA   sing N N 350 
PRO   C   O    doub N N 351 
PRO   C   OXT  sing N N 352 
PRO   CB  CG   sing N N 353 
PRO   CB  HB2  sing N N 354 
PRO   CB  HB3  sing N N 355 
PRO   CG  CD   sing N N 356 
PRO   CG  HG2  sing N N 357 
PRO   CG  HG3  sing N N 358 
PRO   CD  HD2  sing N N 359 
PRO   CD  HD3  sing N N 360 
PRO   OXT HXT  sing N N 361 
SER   N   CA   sing N N 362 
SER   N   H    sing N N 363 
SER   N   H2   sing N N 364 
SER   CA  C    sing N N 365 
SER   CA  CB   sing N N 366 
SER   CA  HA   sing N N 367 
SER   C   O    doub N N 368 
SER   C   OXT  sing N N 369 
SER   CB  OG   sing N N 370 
SER   CB  HB2  sing N N 371 
SER   CB  HB3  sing N N 372 
SER   OG  HG   sing N N 373 
SER   OXT HXT  sing N N 374 
THR   N   CA   sing N N 375 
THR   N   H    sing N N 376 
THR   N   H2   sing N N 377 
THR   CA  C    sing N N 378 
THR   CA  CB   sing N N 379 
THR   CA  HA   sing N N 380 
THR   C   O    doub N N 381 
THR   C   OXT  sing N N 382 
THR   CB  OG1  sing N N 383 
THR   CB  CG2  sing N N 384 
THR   CB  HB   sing N N 385 
THR   OG1 HG1  sing N N 386 
THR   CG2 HG21 sing N N 387 
THR   CG2 HG22 sing N N 388 
THR   CG2 HG23 sing N N 389 
THR   OXT HXT  sing N N 390 
TRP   N   CA   sing N N 391 
TRP   N   H    sing N N 392 
TRP   N   H2   sing N N 393 
TRP   CA  C    sing N N 394 
TRP   CA  CB   sing N N 395 
TRP   CA  HA   sing N N 396 
TRP   C   O    doub N N 397 
TRP   C   OXT  sing N N 398 
TRP   CB  CG   sing N N 399 
TRP   CB  HB2  sing N N 400 
TRP   CB  HB3  sing N N 401 
TRP   CG  CD1  doub Y N 402 
TRP   CG  CD2  sing Y N 403 
TRP   CD1 NE1  sing Y N 404 
TRP   CD1 HD1  sing N N 405 
TRP   CD2 CE2  doub Y N 406 
TRP   CD2 CE3  sing Y N 407 
TRP   NE1 CE2  sing Y N 408 
TRP   NE1 HE1  sing N N 409 
TRP   CE2 CZ2  sing Y N 410 
TRP   CE3 CZ3  doub Y N 411 
TRP   CE3 HE3  sing N N 412 
TRP   CZ2 CH2  doub Y N 413 
TRP   CZ2 HZ2  sing N N 414 
TRP   CZ3 CH2  sing Y N 415 
TRP   CZ3 HZ3  sing N N 416 
TRP   CH2 HH2  sing N N 417 
TRP   OXT HXT  sing N N 418 
TYR   N   CA   sing N N 419 
TYR   N   H    sing N N 420 
TYR   N   H2   sing N N 421 
TYR   CA  C    sing N N 422 
TYR   CA  CB   sing N N 423 
TYR   CA  HA   sing N N 424 
TYR   C   O    doub N N 425 
TYR   C   OXT  sing N N 426 
TYR   CB  CG   sing N N 427 
TYR   CB  HB2  sing N N 428 
TYR   CB  HB3  sing N N 429 
TYR   CG  CD1  doub Y N 430 
TYR   CG  CD2  sing Y N 431 
TYR   CD1 CE1  sing Y N 432 
TYR   CD1 HD1  sing N N 433 
TYR   CD2 CE2  doub Y N 434 
TYR   CD2 HD2  sing N N 435 
TYR   CE1 CZ   doub Y N 436 
TYR   CE1 HE1  sing N N 437 
TYR   CE2 CZ   sing Y N 438 
TYR   CE2 HE2  sing N N 439 
TYR   CZ  OH   sing N N 440 
TYR   OH  HH   sing N N 441 
TYR   OXT HXT  sing N N 442 
VAL   N   CA   sing N N 443 
VAL   N   H    sing N N 444 
VAL   N   H2   sing N N 445 
VAL   CA  C    sing N N 446 
VAL   CA  CB   sing N N 447 
VAL   CA  HA   sing N N 448 
VAL   C   O    doub N N 449 
VAL   C   OXT  sing N N 450 
VAL   CB  CG1  sing N N 451 
VAL   CB  CG2  sing N N 452 
VAL   CB  HB   sing N N 453 
VAL   CG1 HG11 sing N N 454 
VAL   CG1 HG12 sing N N 455 
VAL   CG1 HG13 sing N N 456 
VAL   CG2 HG21 sing N N 457 
VAL   CG2 HG22 sing N N 458 
VAL   CG2 HG23 sing N N 459 
VAL   OXT HXT  sing N N 460 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6PJ3 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 32 2 1' 
_space_group.name_Hall        
;P 32 2"
;
_space_group.IT_number        154 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9CCX 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009378 
_atom_sites.fract_transf_matrix[1][2]   0.005415 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.010829 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.018426 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
F  ? ? 8.95735  ?       ? ? 7.27484  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
MN ? ? 20.23591 4.67902 ? ? 2.76514  44.01191 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ALA   A 1 2   ? -31.53172 -43.57486 8.63145   1.000 48.62903  ? 2   ALA   A N   1 
ATOM   2    C  CA  . ALA   A 1 2   ? -30.83885 -42.48139 7.96336   1.000 46.76258  ? 2   ALA   A CA  1 
ATOM   3    C  C   . ALA   A 1 2   ? -31.63862 -41.19640 8.11865   1.000 41.26142  ? 2   ALA   A C   1 
ATOM   4    O  O   . ALA   A 1 2   ? -32.85470 -41.19027 7.95274   1.000 45.52944  ? 2   ALA   A O   1 
ATOM   5    C  CB  . ALA   A 1 2   ? -30.62173 -42.80618 6.49648   1.000 46.98154  ? 2   ALA   A CB  1 
ATOM   6    N  N   . THR   A 1 3   ? -30.96345 -40.10719 8.45538   1.000 37.83601  ? 3   THR   A N   1 
ATOM   7    C  CA  . THR   A 1 3   ? -31.60441 -38.81189 8.60040   1.000 36.65315  ? 3   THR   A CA  1 
ATOM   8    C  C   . THR   A 1 3   ? -31.14926 -37.89947 7.47093   1.000 48.05511  ? 3   THR   A C   1 
ATOM   9    O  O   . THR   A 1 3   ? -29.96847 -37.89434 7.10541   1.000 39.00929  ? 3   THR   A O   1 
ATOM   10   C  CB  . THR   A 1 3   ? -31.27137 -38.18451 9.95747   1.000 43.46255  ? 3   THR   A CB  1 
ATOM   11   O  OG1 . THR   A 1 3   ? -31.66294 -39.07635 11.00405  1.000 46.52573  ? 3   THR   A OG1 1 
ATOM   12   C  CG2 . THR   A 1 3   ? -32.00430 -36.85321 10.14427  1.000 37.61247  ? 3   THR   A CG2 1 
ATOM   13   N  N   . LEU   A 1 4   ? -32.08743 -37.12882 6.92338   1.000 39.95568  ? 4   LEU   A N   1 
ATOM   14   C  CA  . LEU   A 1 4   ? -31.83567 -36.30770 5.74911   1.000 40.86988  ? 4   LEU   A CA  1 
ATOM   15   C  C   . LEU   A 1 4   ? -31.83399 -34.83644 6.13262   1.000 43.53559  ? 4   LEU   A C   1 
ATOM   16   O  O   . LEU   A 1 4   ? -32.63030 -34.39702 6.96946   1.000 37.17715  ? 4   LEU   A O   1 
ATOM   17   C  CB  . LEU   A 1 4   ? -32.87700 -36.56075 4.64669   1.000 42.66776  ? 4   LEU   A CB  1 
ATOM   18   C  CG  . LEU   A 1 4   ? -33.01241 -37.98121 4.07247   1.000 41.66601  ? 4   LEU   A CG  1 
ATOM   19   C  CD1 . LEU   A 1 4   ? -34.04845 -38.00192 2.96460   1.000 39.48522  ? 4   LEU   A CD1 1 
ATOM   20   C  CD2 . LEU   A 1 4   ? -31.67616 -38.53219 3.56526   1.000 40.97081  ? 4   LEU   A CD2 1 
ATOM   21   N  N   . PHE   A 1 5   ? -30.91225 -34.08845 5.53342   1.000 40.76176  ? 5   PHE   A N   1 
ATOM   22   C  CA  . PHE   A 1 5   ? -30.80102 -32.65676 5.73930   1.000 31.00238  ? 5   PHE   A CA  1 
ATOM   23   C  C   . PHE   A 1 5   ? -30.76483 -31.98534 4.37785   1.000 42.36964  ? 5   PHE   A C   1 
ATOM   24   O  O   . PHE   A 1 5   ? -29.99993 -32.40161 3.49960   1.000 38.75605  ? 5   PHE   A O   1 
ATOM   25   C  CB  . PHE   A 1 5   ? -29.54435 -32.31532 6.55228   1.000 37.48703  ? 5   PHE   A CB  1 
ATOM   26   C  CG  . PHE   A 1 5   ? -29.56624 -32.87286 7.95670   1.000 47.06168  ? 5   PHE   A CG  1 
ATOM   27   C  CD1 . PHE   A 1 5   ? -29.14285 -34.17735 8.21097   1.000 38.47879  ? 5   PHE   A CD1 1 
ATOM   28   C  CD2 . PHE   A 1 5   ? -30.02013 -32.09596 9.02160   1.000 39.73665  ? 5   PHE   A CD2 1 
ATOM   29   C  CE1 . PHE   A 1 5   ? -29.16780 -34.70382 9.50369   1.000 40.36587  ? 5   PHE   A CE1 1 
ATOM   30   C  CE2 . PHE   A 1 5   ? -30.04325 -32.60675 10.31820  1.000 40.29163  ? 5   PHE   A CE2 1 
ATOM   31   C  CZ  . PHE   A 1 5   ? -29.62905 -33.92702 10.55581  1.000 38.72909  ? 5   PHE   A CZ  1 
ATOM   32   N  N   . ILE   A 1 6   ? -31.59426 -30.95041 4.20595   1.000 40.15653  ? 6   ILE   A N   1 
ATOM   33   C  CA  . ILE   A 1 6   ? -31.60604 -30.13049 3.00061   1.000 40.39229  ? 6   ILE   A CA  1 
ATOM   34   C  C   . ILE   A 1 6   ? -31.69644 -28.66715 3.41551   1.000 35.65663  ? 6   ILE   A C   1 
ATOM   35   O  O   . ILE   A 1 6   ? -32.08603 -28.33151 4.53681   1.000 33.93958  ? 6   ILE   A O   1 
ATOM   36   C  CB  . ILE   A 1 6   ? -32.77364 -30.47841 2.03887   1.000 43.08075  ? 6   ILE   A CB  1 
ATOM   37   C  CG1 . ILE   A 1 6   ? -34.11751 -30.26427 2.73331   1.000 34.74907  ? 6   ILE   A CG1 1 
ATOM   38   C  CG2 . ILE   A 1 6   ? -32.65157 -31.90678 1.49786   1.000 35.23440  ? 6   ILE   A CG2 1 
ATOM   39   C  CD1 . ILE   A 1 6   ? -35.32386 -30.61000 1.85430   1.000 28.08007  ? 6   ILE   A CD1 1 
ATOM   40   N  N   . ALA   A 1 7   ? -31.32030 -27.79077 2.49310   1.000 30.73166  ? 7   ALA   A N   1 
ATOM   41   C  CA  . ALA   A 1 7   ? -31.40950 -26.36184 2.74769   1.000 40.12254  ? 7   ALA   A CA  1 
ATOM   42   C  C   . ALA   A 1 7   ? -31.26349 -25.62784 1.42956   1.000 42.06648  ? 7   ALA   A C   1 
ATOM   43   O  O   . ALA   A 1 7   ? -30.80731 -26.19075 0.42803   1.000 40.89111  ? 7   ALA   A O   1 
ATOM   44   C  CB  . ALA   A 1 7   ? -30.33834 -25.88146 3.73865   1.000 34.98034  ? 7   ALA   A CB  1 
ATOM   45   N  N   . ASP   A 1 8   ? -31.68075 -24.36324 1.44685   1.000 45.70140  ? 8   ASP   A N   1 
ATOM   46   C  CA  . ASP   A 1 8   ? -31.30896 -23.39670 0.42875   1.000 35.88237  ? 8   ASP   A CA  1 
ATOM   47   C  C   . ASP   A 1 8   ? -31.87099 -23.79060 -0.93005  1.000 38.95684  ? 8   ASP   A C   1 
ATOM   48   O  O   . ASP   A 1 8   ? -31.17133 -23.74068 -1.94256  1.000 41.43507  ? 8   ASP   A O   1 
ATOM   49   C  CB  . ASP   A 1 8   ? -29.79115 -23.23748 0.35879   1.000 36.50086  ? 8   ASP   A CB  1 
ATOM   50   C  CG  . ASP   A 1 8   ? -29.23099 -22.54699 1.59028   1.000 45.11875  ? 8   ASP   A CG  1 
ATOM   51   O  OD1 . ASP   A 1 8   ? -29.52930 -21.37191 1.81331   1.000 50.07244  ? 8   ASP   A OD1 1 
ATOM   52   O  OD2 . ASP   A 1 8   ? -28.49553 -23.19008 2.36954   1.000 46.58949  ? 8   ASP   A OD2 1 
ATOM   53   N  N   . LEU   A 1 9   ? -33.13780 -24.20204 -0.93761  1.000 41.20990  ? 9   LEU   A N   1 
ATOM   54   C  CA  . LEU   A 1 9   ? -33.84725 -24.52501 -2.16917  1.000 33.73457  ? 9   LEU   A CA  1 
ATOM   55   C  C   . LEU   A 1 9   ? -34.31922 -23.26665 -2.89168  1.000 46.30221  ? 9   LEU   A C   1 
ATOM   56   O  O   . LEU   A 1 9   ? -34.36047 -23.24026 -4.13031  1.000 41.97490  ? 9   LEU   A O   1 
ATOM   57   C  CB  . LEU   A 1 9   ? -35.04316 -25.41491 -1.84450  1.000 36.54327  ? 9   LEU   A CB  1 
ATOM   58   C  CG  . LEU   A 1 9   ? -34.75214 -26.88775 -1.60200  1.000 47.88268  ? 9   LEU   A CG  1 
ATOM   59   C  CD1 . LEU   A 1 9   ? -34.25670 -27.09523 -0.16477  1.000 30.58040  ? 9   LEU   A CD1 1 
ATOM   60   C  CD2 . LEU   A 1 9   ? -36.00471 -27.73272 -1.90998  1.000 35.53853  ? 9   LEU   A CD2 1 
ATOM   61   N  N   . HIS   A 1 10  ? -34.70842 -22.23067 -2.13224  1.000 33.49673  ? 10  HIS   A N   1 
ATOM   62   C  CA  . HIS   A 1 10  ? -35.18209 -20.96617 -2.69873  1.000 35.95592  ? 10  HIS   A CA  1 
ATOM   63   C  C   . HIS   A 1 10  ? -36.33624 -21.17185 -3.67692  1.000 33.10324  ? 10  HIS   A C   1 
ATOM   64   O  O   . HIS   A 1 10  ? -36.34818 -20.61793 -4.78066  1.000 38.43848  ? 10  HIS   A O   1 
ATOM   65   C  CB  . HIS   A 1 10  ? -34.03363 -20.22462 -3.37503  1.000 37.59943  ? 10  HIS   A CB  1 
ATOM   66   C  CG  . HIS   A 1 10  ? -32.81235 -20.13099 -2.52582  1.000 49.64861  ? 10  HIS   A CG  1 
ATOM   67   N  ND1 . HIS   A 1 10  ? -31.67309 -20.86251 -2.78187  1.000 49.77318  ? 10  HIS   A ND1 1 
ATOM   68   C  CD2 . HIS   A 1 10  ? -32.55245 -19.39826 -1.41782  1.000 47.30805  ? 10  HIS   A CD2 1 
ATOM   69   C  CE1 . HIS   A 1 10  ? -30.76272 -20.58457 -1.86615  1.000 51.25222  ? 10  HIS   A CE1 1 
ATOM   70   N  NE2 . HIS   A 1 10  ? -31.27400 -19.70497 -1.02411  1.000 46.90775  ? 10  HIS   A NE2 1 
ATOM   71   N  N   . LEU   A 1 11  ? -37.31207 -21.97597 -3.26117  1.000 37.08155  ? 11  LEU   A N   1 
ATOM   72   C  CA  . LEU   A 1 11  ? -38.48146 -22.23093 -4.09566  1.000 40.37318  ? 11  LEU   A CA  1 
ATOM   73   C  C   . LEU   A 1 11  ? -39.17470 -20.91899 -4.44004  1.000 39.19632  ? 11  LEU   A C   1 
ATOM   74   O  O   . LEU   A 1 11  ? -39.26672 -20.01554 -3.60736  1.000 36.23374  ? 11  LEU   A O   1 
ATOM   75   C  CB  . LEU   A 1 11  ? -39.46005 -23.16250 -3.37897  1.000 34.77436  ? 11  LEU   A CB  1 
ATOM   76   C  CG  . LEU   A 1 11  ? -38.93523 -24.56321 -3.04398  1.000 42.92744  ? 11  LEU   A CG  1 
ATOM   77   C  CD1 . LEU   A 1 11  ? -39.94115 -25.27374 -2.16427  1.000 44.57493  ? 11  LEU   A CD1 1 
ATOM   78   C  CD2 . LEU   A 1 11  ? -38.63849 -25.38600 -4.29534  1.000 34.36046  ? 11  LEU   A CD2 1 
ATOM   79   N  N   . GLN   A 1 12  ? -39.64822 -20.82017 -5.68295  1.000 37.43619  ? 12  GLN   A N   1 
ATOM   80   C  CA  . GLN   A 1 12  ? -40.29987 -19.63721 -6.22369  1.000 44.40409  ? 12  GLN   A CA  1 
ATOM   81   C  C   . GLN   A 1 12  ? -40.97767 -20.05326 -7.52145  1.000 47.03348  ? 12  GLN   A C   1 
ATOM   82   O  O   . GLN   A 1 12  ? -40.47537 -20.92541 -8.24048  1.000 44.63233  ? 12  GLN   A O   1 
ATOM   83   C  CB  . GLN   A 1 12  ? -39.30125 -18.50415 -6.48320  1.000 39.42937  ? 12  GLN   A CB  1 
ATOM   84   C  CG  . GLN   A 1 12  ? -38.19960 -18.90254 -7.44995  1.000 44.57092  ? 12  GLN   A CG  1 
ATOM   85   C  CD  . GLN   A 1 12  ? -37.13106 -17.84235 -7.63035  1.000 55.81089  ? 12  GLN   A CD  1 
ATOM   86   O  OE1 . GLN   A 1 12  ? -36.03479 -17.95868 -7.08542  1.000 52.55546  ? 12  GLN   A OE1 1 
ATOM   87   N  NE2 . GLN   A 1 12  ? -37.42974 -16.82563 -8.42870  1.000 58.14609  ? 12  GLN   A NE2 1 
ATOM   88   N  N   . THR   A 1 13  ? -42.11943 -19.42291 -7.81716  1.000 39.72720  ? 13  THR   A N   1 
ATOM   89   C  CA  . THR   A 1 13  ? -42.92219 -19.84963 -8.96163  1.000 42.55270  ? 13  THR   A CA  1 
ATOM   90   C  C   . THR   A 1 13  ? -42.20579 -19.63867 -10.28876 1.000 44.09377  ? 13  THR   A C   1 
ATOM   91   O  O   . THR   A 1 13  ? -42.51664 -20.33211 -11.26287 1.000 42.47018  ? 13  THR   A O   1 
ATOM   92   C  CB  . THR   A 1 13  ? -44.26365 -19.11323 -8.98732  1.000 44.75381  ? 13  THR   A CB  1 
ATOM   93   O  OG1 . THR   A 1 13  ? -44.03872 -17.71544 -8.79028  1.000 46.23752  ? 13  THR   A OG1 1 
ATOM   94   C  CG2 . THR   A 1 13  ? -45.16948 -19.62710 -7.87447  1.000 47.05081  ? 13  THR   A CG2 1 
ATOM   95   N  N   . GLU   A 1 14  ? -41.25772 -18.70275 -10.35082 1.000 40.38300  ? 14  GLU   A N   1 
ATOM   96   C  CA  . GLU   A 1 14  ? -40.45037 -18.48635 -11.54825 1.000 51.15288  ? 14  GLU   A CA  1 
ATOM   97   C  C   . GLU   A 1 14  ? -39.46278 -19.61602 -11.82806 1.000 46.69009  ? 14  GLU   A C   1 
ATOM   98   O  O   . GLU   A 1 14  ? -38.89826 -19.66132 -12.92392 1.000 48.98784  ? 14  GLU   A O   1 
ATOM   99   C  CB  . GLU   A 1 14  ? -39.68534 -17.17032 -11.41009 1.000 54.66501  ? 14  GLU   A CB  1 
ATOM   100  C  CG  . GLU   A 1 14  ? -40.57884 -15.95224 -11.43669 1.000 61.76738  ? 14  GLU   A CG  1 
ATOM   101  C  CD  . GLU   A 1 14  ? -40.70014 -15.31655 -10.07767 1.000 72.02556  ? 14  GLU   A CD  1 
ATOM   102  O  OE1 . GLU   A 1 14  ? -40.31466 -15.98302 -9.08928  1.000 70.94214  ? 14  GLU   A OE1 1 
ATOM   103  O  OE2 . GLU   A 1 14  ? -41.16762 -14.15423 -10.00197 1.000 89.00515  ? 14  GLU   A OE2 1 
ATOM   104  N  N   . GLU   A 1 15  ? -39.23196 -20.52048 -10.87914 1.000 46.86693  ? 15  GLU   A N   1 
ATOM   105  C  CA  . GLU   A 1 15  ? -38.32567 -21.65239 -11.06256 1.000 45.99343  ? 15  GLU   A CA  1 
ATOM   106  C  C   . GLU   A 1 15  ? -39.08058 -22.96497 -10.87118 1.000 47.97753  ? 15  GLU   A C   1 
ATOM   107  O  O   . GLU   A 1 15  ? -38.82888 -23.70005 -9.90692  1.000 39.73232  ? 15  GLU   A O   1 
ATOM   108  C  CB  . GLU   A 1 15  ? -37.14312 -21.57284 -10.09773 1.000 47.64856  ? 15  GLU   A CB  1 
ATOM   109  C  CG  . GLU   A 1 15  ? -36.29334 -20.31788 -10.24469 1.000 50.95208  ? 15  GLU   A CG  1 
ATOM   110  C  CD  . GLU   A 1 15  ? -35.54107 -20.28510 -11.56104 1.000 65.20970  ? 15  GLU   A CD  1 
ATOM   111  O  OE1 . GLU   A 1 15  ? -35.02423 -19.20440 -11.92048 1.000 83.13288  ? 15  GLU   A OE1 1 
ATOM   112  O  OE2 . GLU   A 1 15  ? -35.45132 -21.34293 -12.22734 1.000 63.09491  ? 15  GLU   A OE2 1 
ATOM   113  N  N   . PRO   A 1 16  ? -40.00070 -23.30377 -11.78238 1.000 52.78123  ? 16  PRO   A N   1 
ATOM   114  C  CA  . PRO   A 1 16  ? -40.78312 -24.53509 -11.58571 1.000 47.46219  ? 16  PRO   A CA  1 
ATOM   115  C  C   . PRO   A 1 16  ? -39.94462 -25.80995 -11.54935 1.000 47.32657  ? 16  PRO   A C   1 
ATOM   116  O  O   . PRO   A 1 16  ? -40.35858 -26.76669 -10.88829 1.000 53.79812  ? 16  PRO   A O   1 
ATOM   117  C  CB  . PRO   A 1 16  ? -41.76876 -24.52169 -12.76450 1.000 43.43116  ? 16  PRO   A CB  1 
ATOM   118  C  CG  . PRO   A 1 16  ? -41.12606 -23.65070 -13.79336 1.000 44.68275  ? 16  PRO   A CG  1 
ATOM   119  C  CD  . PRO   A 1 16  ? -40.36302 -22.60923 -13.03506 1.000 42.67497  ? 16  PRO   A CD  1 
ATOM   120  N  N   . ALA   A 1 17  ? -38.76807 -25.84982 -12.18183 1.000 42.87355  ? 17  ALA   A N   1 
ATOM   121  C  CA  . ALA   A 1 17  ? -37.96632 -27.07514 -12.17137 1.000 44.24549  ? 17  ALA   A CA  1 
ATOM   122  C  C   . ALA   A 1 17  ? -37.47877 -27.42717 -10.76785 1.000 56.47455  ? 17  ALA   A C   1 
ATOM   123  O  O   . ALA   A 1 17  ? -37.39528 -28.61130 -10.41280 1.000 47.92289  ? 17  ALA   A O   1 
ATOM   124  C  CB  . ALA   A 1 17  ? -36.77495 -26.94881 -13.12199 1.000 48.16518  ? 17  ALA   A CB  1 
ATOM   125  N  N   . ILE   A 1 18  ? -37.13435 -26.42500 -9.95854  1.000 48.33411  ? 18  ILE   A N   1 
ATOM   126  C  CA  . ILE   A 1 18  ? -36.73946 -26.71699 -8.58414  1.000 51.71128  ? 18  ILE   A CA  1 
ATOM   127  C  C   . ILE   A 1 18  ? -37.92336 -27.27736 -7.80205  1.000 50.10845  ? 18  ILE   A C   1 
ATOM   128  O  O   . ILE   A 1 18  ? -37.78426 -28.24352 -7.03907  1.000 40.89327  ? 18  ILE   A O   1 
ATOM   129  C  CB  . ILE   A 1 18  ? -36.14996 -25.46241 -7.91157  1.000 50.53681  ? 18  ILE   A CB  1 
ATOM   130  C  CG1 . ILE   A 1 18  ? -34.84816 -25.04462 -8.59498  1.000 52.47809  ? 18  ILE   A CG1 1 
ATOM   131  C  CG2 . ILE   A 1 18  ? -35.87229 -25.71946 -6.44429  1.000 55.51203  ? 18  ILE   A CG2 1 
ATOM   132  C  CD1 . ILE   A 1 18  ? -34.49602 -23.57569 -8.39501  1.000 48.56296  ? 18  ILE   A CD1 1 
ATOM   133  N  N   . THR   A 1 19  ? -39.10919 -26.69036 -7.98539  1.000 45.25106  ? 19  THR   A N   1 
ATOM   134  C  CA  . THR   A 1 19  ? -40.30020 -27.19476 -7.30357  1.000 48.19002  ? 19  THR   A CA  1 
ATOM   135  C  C   . THR   A 1 19  ? -40.58568 -28.64368 -7.69046  1.000 45.67996  ? 19  THR   A C   1 
ATOM   136  O  O   . THR   A 1 19  ? -40.82252 -29.49775 -6.82580  1.000 39.78843  ? 19  THR   A O   1 
ATOM   137  C  CB  . THR   A 1 19  ? -41.50149 -26.30721 -7.62706  1.000 39.50225  ? 19  THR   A CB  1 
ATOM   138  O  OG1 . THR   A 1 19  ? -41.25390 -24.98289 -7.13872  1.000 44.96411  ? 19  THR   A OG1 1 
ATOM   139  C  CG2 . THR   A 1 19  ? -42.75513 -26.86900 -6.99036  1.000 34.15924  ? 19  THR   A CG2 1 
ATOM   140  N  N   . ALA   A 1 20  ? -40.56671 -28.93870 -8.99432  1.000 40.83641  ? 20  ALA   A N   1 
ATOM   141  C  CA  . ALA   A 1 20  ? -40.75319 -30.31353 -9.44970  1.000 49.85263  ? 20  ALA   A CA  1 
ATOM   142  C  C   . ALA   A 1 20  ? -39.68520 -31.23591 -8.87262  1.000 50.54592  ? 20  ALA   A C   1 
ATOM   143  O  O   . ALA   A 1 20  ? -39.97451 -32.38355 -8.50967  1.000 56.08284  ? 20  ALA   A O   1 
ATOM   144  C  CB  . ALA   A 1 20  ? -40.74272 -30.36191 -10.97863 1.000 42.26927  ? 20  ALA   A CB  1 
ATOM   145  N  N   . GLY   A 1 21  ? -38.44789 -30.74802 -8.76488  1.000 47.26300  ? 21  GLY   A N   1 
ATOM   146  C  CA  . GLY   A 1 21  ? -37.39120 -31.56516 -8.18479  1.000 38.34204  ? 21  GLY   A CA  1 
ATOM   147  C  C   . GLY   A 1 21  ? -37.60446 -31.82947 -6.70579  1.000 42.26756  ? 21  GLY   A C   1 
ATOM   148  O  O   . GLY   A 1 21  ? -37.33767 -32.93028 -6.21504  1.000 36.71711  ? 21  GLY   A O   1 
ATOM   149  N  N   . PHE   A 1 22  ? -38.09361 -30.82768 -5.97205  1.000 40.83480  ? 22  PHE   A N   1 
ATOM   150  C  CA  . PHE   A 1 22  ? -38.36841 -31.03072 -4.55197  1.000 41.62462  ? 22  PHE   A CA  1 
ATOM   151  C  C   . PHE   A 1 22  ? -39.51846 -32.01041 -4.35534  1.000 48.95233  ? 22  PHE   A C   1 
ATOM   152  O  O   . PHE   A 1 22  ? -39.47139 -32.86300 -3.45888  1.000 39.78541  ? 22  PHE   A O   1 
ATOM   153  C  CB  . PHE   A 1 22  ? -38.67653 -29.69166 -3.88811  1.000 38.01063  ? 22  PHE   A CB  1 
ATOM   154  C  CG  . PHE   A 1 22  ? -38.89524 -29.76729 -2.39373  1.000 36.69792  ? 22  PHE   A CG  1 
ATOM   155  C  CD1 . PHE   A 1 22  ? -38.04902 -30.50437 -1.58372  1.000 39.60966  ? 22  PHE   A CD1 1 
ATOM   156  C  CD2 . PHE   A 1 22  ? -39.94998 -29.07398 -1.80285  1.000 38.42860  ? 22  PHE   A CD2 1 
ATOM   157  C  CE1 . PHE   A 1 22  ? -38.24165 -30.54551 -0.20875  1.000 39.36968  ? 22  PHE   A CE1 1 
ATOM   158  C  CE2 . PHE   A 1 22  ? -40.14700 -29.10678 -0.42478  1.000 35.33836  ? 22  PHE   A CE2 1 
ATOM   159  C  CZ  . PHE   A 1 22  ? -39.29218 -29.84568 0.37110   1.000 41.78560  ? 22  PHE   A CZ  1 
ATOM   160  N  N   . LEU   A 1 23  ? -40.54950 -31.91199 -5.20052  1.000 43.86694  ? 23  LEU   A N   1 
ATOM   161  C  CA  . LEU   A 1 23  ? -41.70022 -32.80517 -5.09814  1.000 44.57980  ? 23  LEU   A CA  1 
ATOM   162  C  C   . LEU   A 1 23  ? -41.29057 -34.24795 -5.35205  1.000 50.40454  ? 23  LEU   A C   1 
ATOM   163  O  O   . LEU   A 1 23  ? -41.69950 -35.15562 -4.61955  1.000 45.68594  ? 23  LEU   A O   1 
ATOM   164  C  CB  . LEU   A 1 23  ? -42.77451 -32.39073 -6.10196  1.000 38.96540  ? 23  LEU   A CB  1 
ATOM   165  C  CG  . LEU   A 1 23  ? -43.52064 -31.09167 -5.78771  1.000 51.67053  ? 23  LEU   A CG  1 
ATOM   166  C  CD1 . LEU   A 1 23  ? -44.46384 -30.70463 -6.94178  1.000 51.09268  ? 23  LEU   A CD1 1 
ATOM   167  C  CD2 . LEU   A 1 23  ? -44.23690 -31.15800 -4.46761  1.000 42.51573  ? 23  LEU   A CD2 1 
ATOM   168  N  N   . ARG   A 1 24  ? -40.48103 -34.47303 -6.39252  1.000 50.17539  ? 24  ARG   A N   1 
ATOM   169  C  CA  . ARG   A 1 24  ? -39.92890 -35.79759 -6.65409  1.000 49.24481  ? 24  ARG   A CA  1 
ATOM   170  C  C   . ARG   A 1 24  ? -39.08658 -36.29472 -5.48121  1.000 53.77495  ? 24  ARG   A C   1 
ATOM   171  O  O   . ARG   A 1 24  ? -39.16268 -37.46997 -5.10821  1.000 46.58904  ? 24  ARG   A O   1 
ATOM   172  C  CB  . ARG   A 1 24  ? -39.10799 -35.75821 -7.94013  1.000 46.26804  ? 24  ARG   A CB  1 
ATOM   173  C  CG  . ARG   A 1 24  ? -38.61033 -37.11151 -8.39347  1.000 55.51896  ? 24  ARG   A CG  1 
ATOM   174  C  CD  . ARG   A 1 24  ? -37.14883 -37.03324 -8.81581  1.000 56.80857  ? 24  ARG   A CD  1 
ATOM   175  N  N   . PHE   A 1 25  ? -38.27472 -35.41445 -4.88819  1.000 52.93065  ? 25  PHE   A N   1 
ATOM   176  C  CA  . PHE   A 1 25  ? -37.50954 -35.78566 -3.69995  1.000 40.70415  ? 25  PHE   A CA  1 
ATOM   177  C  C   . PHE   A 1 25  ? -38.43380 -36.25432 -2.57632  1.000 52.10409  ? 25  PHE   A C   1 
ATOM   178  O  O   . PHE   A 1 25  ? -38.20486 -37.30423 -1.96077  1.000 47.71658  ? 25  PHE   A O   1 
ATOM   179  C  CB  . PHE   A 1 25  ? -36.65662 -34.59022 -3.25970  1.000 39.26685  ? 25  PHE   A CB  1 
ATOM   180  C  CG  . PHE   A 1 25  ? -36.05638 -34.72389 -1.88401  1.000 45.73047  ? 25  PHE   A CG  1 
ATOM   181  C  CD1 . PHE   A 1 25  ? -34.82595 -35.36603 -1.70421  1.000 48.08370  ? 25  PHE   A CD1 1 
ATOM   182  C  CD2 . PHE   A 1 25  ? -36.69806 -34.17947 -0.77229  1.000 33.47114  ? 25  PHE   A CD2 1 
ATOM   183  C  CE1 . PHE   A 1 25  ? -34.25707 -35.48908 -0.43351  1.000 40.05069  ? 25  PHE   A CE1 1 
ATOM   184  C  CE2 . PHE   A 1 25  ? -36.14245 -34.28864 0.50290   1.000 48.58228  ? 25  PHE   A CE2 1 
ATOM   185  C  CZ  . PHE   A 1 25  ? -34.91481 -34.95320 0.67640   1.000 46.41419  ? 25  PHE   A CZ  1 
ATOM   186  N  N   . LEU   A 1 26  ? -39.49780 -35.48992 -2.30923  1.000 42.34995  ? 26  LEU   A N   1 
ATOM   187  C  CA  . LEU   A 1 26  ? -40.40468 -35.81708 -1.21030  1.000 48.26947  ? 26  LEU   A CA  1 
ATOM   188  C  C   . LEU   A 1 26  ? -41.10364 -37.15119 -1.42639  1.000 55.56332  ? 26  LEU   A C   1 
ATOM   189  O  O   . LEU   A 1 26  ? -41.28433 -37.92268 -0.47550  1.000 59.14295  ? 26  LEU   A O   1 
ATOM   190  C  CB  . LEU   A 1 26  ? -41.45345 -34.71719 -1.02780  1.000 40.50666  ? 26  LEU   A CB  1 
ATOM   191  C  CG  . LEU   A 1 26  ? -40.96815 -33.36974 -0.48618  1.000 42.21788  ? 26  LEU   A CG  1 
ATOM   192  C  CD1 . LEU   A 1 26  ? -42.13719 -32.41497 -0.29947  1.000 34.29350  ? 26  LEU   A CD1 1 
ATOM   193  C  CD2 . LEU   A 1 26  ? -40.20597 -33.56830 0.80871   1.000 33.30499  ? 26  LEU   A CD2 1 
ATOM   194  N  N   . GLN   A 1 27  ? -41.52919 -37.42799 -2.66180  1.000 51.96785  ? 27  GLN   A N   1 
ATOM   195  C  CA  . GLN   A 1 27  ? -42.23295 -38.66084 -2.98852  1.000 48.77525  ? 27  GLN   A CA  1 
ATOM   196  C  C   . GLN   A 1 27  ? -41.29337 -39.84538 -3.19247  1.000 61.01497  ? 27  GLN   A C   1 
ATOM   197  O  O   . GLN   A 1 27  ? -41.77227 -40.95562 -3.43979  1.000 62.01810  ? 27  GLN   A O   1 
ATOM   198  C  CB  . GLN   A 1 27  ? -43.09370 -38.45912 -4.24016  1.000 49.03995  ? 27  GLN   A CB  1 
ATOM   199  N  N   . GLY   A 1 28  ? -39.98153 -39.64596 -3.08351  1.000 48.16419  ? 28  GLY   A N   1 
ATOM   200  C  CA  . GLY   A 1 28  ? -39.03185 -40.72359 -3.26743  1.000 54.78197  ? 28  GLY   A CA  1 
ATOM   201  C  C   . GLY   A 1 28  ? -38.07218 -40.91930 -2.10912  1.000 58.75197  ? 28  GLY   A C   1 
ATOM   202  O  O   . GLY   A 1 28  ? -38.18130 -41.89296 -1.36228  1.000 81.54120  ? 28  GLY   A O   1 
ATOM   203  N  N   . GLU   A 1 29  ? -37.12410 -40.00094 -1.94395  1.000 52.50496  ? 29  GLU   A N   1 
ATOM   204  C  CA  . GLU   A 1 29  ? -36.11391 -40.16406 -0.90465  1.000 58.86666  ? 29  GLU   A CA  1 
ATOM   205  C  C   . GLU   A 1 29  ? -36.71079 -39.97840 0.48634   1.000 44.06161  ? 29  GLU   A C   1 
ATOM   206  O  O   . GLU   A 1 29  ? -36.49528 -40.80450 1.37757   1.000 52.43492  ? 29  GLU   A O   1 
ATOM   207  C  CB  . GLU   A 1 29  ? -34.96369 -39.17543 -1.13503  1.000 53.68494  ? 29  GLU   A CB  1 
ATOM   208  N  N   . ALA   A 1 30  ? -37.46092 -38.89413 0.69281   1.000 48.39692  ? 30  ALA   A N   1 
ATOM   209  C  CA  . ALA   A 1 30  ? -37.88248 -38.52302 2.04272   1.000 48.58839  ? 30  ALA   A CA  1 
ATOM   210  C  C   . ALA   A 1 30  ? -38.79583 -39.56769 2.68606   1.000 51.11744  ? 30  ALA   A C   1 
ATOM   211  O  O   . ALA   A 1 30  ? -38.77459 -39.72491 3.91546   1.000 45.67871  ? 30  ALA   A O   1 
ATOM   212  C  CB  . ALA   A 1 30  ? -38.57281 -37.15998 2.01161   1.000 47.51543  ? 30  ALA   A CB  1 
ATOM   213  N  N   . ARG   A 1 31  ? -39.59827 -40.28584 1.88692   1.000 44.32309  ? 31  ARG   A N   1 
ATOM   214  C  CA  . ARG   A 1 31  ? -40.49709 -41.29683 2.44201   1.000 50.60821  ? 31  ARG   A CA  1 
ATOM   215  C  C   . ARG   A 1 31  ? -39.75303 -42.41082 3.17007   1.000 49.50078  ? 31  ARG   A C   1 
ATOM   216  O  O   . ARG   A 1 31  ? -40.34957 -43.09794 4.00545   1.000 49.81043  ? 31  ARG   A O   1 
ATOM   217  C  CB  . ARG   A 1 31  ? -41.35646 -41.91855 1.33428   1.000 55.54959  ? 31  ARG   A CB  1 
ATOM   218  C  CG  . ARG   A 1 31  ? -42.14139 -40.90769 0.52968   1.000 62.43335  ? 31  ARG   A CG  1 
ATOM   219  C  CD  . ARG   A 1 31  ? -43.29406 -40.34472 1.33836   1.000 69.69434  ? 31  ARG   A CD  1 
ATOM   220  N  NE  . ARG   A 1 31  ? -44.04416 -39.34036 0.58878   1.000 75.36742  ? 31  ARG   A NE  1 
ATOM   221  C  CZ  . ARG   A 1 31  ? -45.28594 -39.49020 0.15173   1.000 77.35170  ? 31  ARG   A CZ  1 
ATOM   222  N  NH1 . ARG   A 1 31  ? -45.97196 -40.59897 0.39154   1.000 67.20231  ? 31  ARG   A NH1 1 
ATOM   223  N  NH2 . ARG   A 1 31  ? -45.85471 -38.49753 -0.53394  1.000 61.11825  ? 31  ARG   A NH2 1 
ATOM   224  N  N   . GLN   A 1 32  ? -38.47441 -42.61672 2.87123   1.000 49.74699  ? 32  GLN   A N   1 
ATOM   225  C  CA  . GLN   A 1 32  ? -37.70977 -43.70593 3.46050   1.000 55.60661  ? 32  GLN   A CA  1 
ATOM   226  C  C   . GLN   A 1 32  ? -36.83911 -43.26148 4.62646   1.000 49.91174  ? 32  GLN   A C   1 
ATOM   227  O  O   . GLN   A 1 32  ? -36.08385 -44.07369 5.15699   1.000 47.68790  ? 32  GLN   A O   1 
ATOM   228  C  CB  . GLN   A 1 32  ? -36.85405 -44.37847 2.38828   1.000 53.66193  ? 32  GLN   A CB  1 
ATOM   229  C  CG  . GLN   A 1 32  ? -37.60003 -44.58102 1.07171   1.000 72.50016  ? 32  GLN   A CG  1 
ATOM   230  C  CD  . GLN   A 1 32  ? -36.73189 -45.19349 -0.01179  1.000 83.25405  ? 32  GLN   A CD  1 
ATOM   231  O  OE1 . GLN   A 1 32  ? -35.96022 -46.11481 0.25004   1.000 81.69079  ? 32  GLN   A OE1 1 
ATOM   232  N  NE2 . GLN   A 1 32  ? -36.85600 -44.68677 -1.23677  1.000 85.35671  ? 32  GLN   A NE2 1 
ATOM   233  N  N   . ALA   A 1 33  ? -36.95365 -42.00877 5.05646   1.000 40.36298  ? 33  ALA   A N   1 
ATOM   234  C  CA  . ALA   A 1 33  ? -36.06923 -41.43207 6.05998   1.000 40.40354  ? 33  ALA   A CA  1 
ATOM   235  C  C   . ALA   A 1 33  ? -36.63121 -41.60723 7.46820   1.000 45.21584  ? 33  ALA   A C   1 
ATOM   236  O  O   . ALA   A 1 33  ? -37.84478 -41.70028 7.66634   1.000 46.48765  ? 33  ALA   A O   1 
ATOM   237  C  CB  . ALA   A 1 33  ? -35.86223 -39.93668 5.77717   1.000 35.85489  ? 33  ALA   A CB  1 
ATOM   238  N  N   . ASP   A 1 34  ? -35.73162 -41.63568 8.45805   1.000 39.81544  ? 34  ASP   A N   1 
ATOM   239  C  CA  . ASP   A 1 34  ? -36.17135 -41.57003 9.85174   1.000 46.31817  ? 34  ASP   A CA  1 
ATOM   240  C  C   . ASP   A 1 34  ? -36.66792 -40.17334 10.23135  1.000 54.37671  ? 34  ASP   A C   1 
ATOM   241  O  O   . ASP   A 1 34  ? -37.42448 -40.03521 11.20580  1.000 43.30868  ? 34  ASP   A O   1 
ATOM   242  C  CB  . ASP   A 1 34  ? -35.03918 -41.96818 10.80121  1.000 46.84566  ? 34  ASP   A CB  1 
ATOM   243  C  CG  . ASP   A 1 34  ? -34.46541 -43.34672 10.50490  1.000 54.46485  ? 34  ASP   A CG  1 
ATOM   244  O  OD1 . ASP   A 1 34  ? -35.14205 -44.18337 9.86988   1.000 52.00013  ? 34  ASP   A OD1 1 
ATOM   245  O  OD2 . ASP   A 1 34  ? -33.32158 -43.59817 10.93095  1.000 45.33160  ? 34  ASP   A OD2 1 
ATOM   246  N  N   . ALA   A 1 35  ? -36.24974 -39.14548 9.49166   1.000 40.51452  ? 35  ALA   A N   1 
ATOM   247  C  CA  . ALA   A 1 35  ? -36.59005 -37.75474 9.76856   1.000 44.11211  ? 35  ALA   A CA  1 
ATOM   248  C  C   . ALA   A 1 35  ? -36.03442 -36.89782 8.64251   1.000 43.61292  ? 35  ALA   A C   1 
ATOM   249  O  O   . ALA   A 1 35  ? -35.07045 -37.28112 7.97061   1.000 40.40350  ? 35  ALA   A O   1 
ATOM   250  C  CB  . ALA   A 1 35  ? -36.02966 -37.28273 11.11882  1.000 43.33731  ? 35  ALA   A CB  1 
ATOM   251  N  N   . LEU   A 1 36  ? -36.64092 -35.72228 8.46336   1.000 36.56743  ? 36  LEU   A N   1 
ATOM   252  C  CA  . LEU   A 1 36  ? -36.23168 -34.75726 7.44785   1.000 42.80225  ? 36  LEU   A CA  1 
ATOM   253  C  C   . LEU   A 1 36  ? -36.07819 -33.38623 8.09659   1.000 45.79052  ? 36  LEU   A C   1 
ATOM   254  O  O   . LEU   A 1 36  ? -37.04842 -32.83180 8.63111   1.000 39.92575  ? 36  LEU   A O   1 
ATOM   255  C  CB  . LEU   A 1 36  ? -37.25125 -34.69160 6.29807   1.000 40.56871  ? 36  LEU   A CB  1 
ATOM   256  C  CG  . LEU   A 1 36  ? -37.02625 -33.56375 5.27959   1.000 47.55651  ? 36  LEU   A CG  1 
ATOM   257  C  CD1 . LEU   A 1 36  ? -35.63143 -33.67742 4.62667   1.000 43.70518  ? 36  LEU   A CD1 1 
ATOM   258  C  CD2 . LEU   A 1 36  ? -38.11042 -33.56325 4.21231   1.000 41.57071  ? 36  LEU   A CD2 1 
ATOM   259  N  N   . TYR   A 1 37  ? -34.87143 -32.83502 8.03948   1.000 41.26665  ? 37  TYR   A N   1 
ATOM   260  C  CA  . TYR   A 1 37  ? -34.59090 -31.49870 8.54993   1.000 35.62342  ? 37  TYR   A CA  1 
ATOM   261  C  C   . TYR   A 1 37  ? -34.33041 -30.56408 7.38121   1.000 36.47725  ? 37  TYR   A C   1 
ATOM   262  O  O   . TYR   A 1 37  ? -33.48931 -30.86000 6.52414   1.000 39.88070  ? 37  TYR   A O   1 
ATOM   263  C  CB  . TYR   A 1 37  ? -33.37928 -31.49879 9.47857   1.000 33.73552  ? 37  TYR   A CB  1 
ATOM   264  C  CG  . TYR   A 1 37  ? -33.60872 -32.18882 10.80094  1.000 41.41903  ? 37  TYR   A CG  1 
ATOM   265  C  CD1 . TYR   A 1 37  ? -33.54349 -33.58419 10.90075  1.000 39.71254  ? 37  TYR   A CD1 1 
ATOM   266  C  CD2 . TYR   A 1 37  ? -33.86985 -31.44994 11.95489  1.000 35.58073  ? 37  TYR   A CD2 1 
ATOM   267  C  CE1 . TYR   A 1 37  ? -33.74302 -34.22707 12.11228  1.000 31.65703  ? 37  TYR   A CE1 1 
ATOM   268  C  CE2 . TYR   A 1 37  ? -34.06478 -32.07688 13.17473  1.000 43.06056  ? 37  TYR   A CE2 1 
ATOM   269  C  CZ  . TYR   A 1 37  ? -34.00149 -33.46980 13.24596  1.000 47.52678  ? 37  TYR   A CZ  1 
ATOM   270  O  OH  . TYR   A 1 37  ? -34.19949 -34.10624 14.45107  1.000 43.64875  ? 37  TYR   A OH  1 
ATOM   271  N  N   . ILE   A 1 38  ? -35.05511 -29.44687 7.35453   1.000 34.51802  ? 38  ILE   A N   1 
ATOM   272  C  CA  . ILE   A 1 38  ? -34.88895 -28.38395 6.37061   1.000 33.93155  ? 38  ILE   A CA  1 
ATOM   273  C  C   . ILE   A 1 38  ? -34.30445 -27.19037 7.11275   1.000 37.29841  ? 38  ILE   A C   1 
ATOM   274  O  O   . ILE   A 1 38  ? -34.99839 -26.54539 7.90969   1.000 40.22952  ? 38  ILE   A O   1 
ATOM   275  C  CB  . ILE   A 1 38  ? -36.21886 -28.02434 5.69735   1.000 38.02369  ? 38  ILE   A CB  1 
ATOM   276  C  CG1 . ILE   A 1 38  ? -36.92248 -29.29529 5.19389   1.000 35.15688  ? 38  ILE   A CG1 1 
ATOM   277  C  CG2 . ILE   A 1 38  ? -36.00558 -27.03446 4.58654   1.000 32.20565  ? 38  ILE   A CG2 1 
ATOM   278  C  CD1 . ILE   A 1 38  ? -38.22435 -29.02859 4.46892   1.000 36.01567  ? 38  ILE   A CD1 1 
ATOM   279  N  N   . LEU   A 1 39  ? -33.03240 -26.89239 6.85361   1.000 39.46725  ? 39  LEU   A N   1 
ATOM   280  C  CA  . LEU   A 1 39  ? -32.27357 -25.88303 7.60028   1.000 34.78878  ? 39  LEU   A CA  1 
ATOM   281  C  C   . LEU   A 1 39  ? -32.34139 -24.49922 6.95241   1.000 41.31963  ? 39  LEU   A C   1 
ATOM   282  O  O   . LEU   A 1 39  ? -31.32643 -23.81943 6.80379   1.000 46.78941  ? 39  LEU   A O   1 
ATOM   283  C  CB  . LEU   A 1 39  ? -30.82381 -26.34033 7.74760   1.000 44.26386  ? 39  LEU   A CB  1 
ATOM   284  C  CG  . LEU   A 1 39  ? -30.61059 -27.76398 8.29609   1.000 46.70024  ? 39  LEU   A CG  1 
ATOM   285  C  CD1 . LEU   A 1 39  ? -29.13117 -28.04877 8.55825   1.000 40.82375  ? 39  LEU   A CD1 1 
ATOM   286  C  CD2 . LEU   A 1 39  ? -31.42810 -27.99149 9.55492   1.000 36.38982  ? 39  LEU   A CD2 1 
ATOM   287  N  N   . GLY   A 1 40  ? -33.53297 -24.06066 6.56717   1.000 39.54432  ? 40  GLY   A N   1 
ATOM   288  C  CA  . GLY   A 1 40  ? -33.72905 -22.68087 6.17521   1.000 35.00014  ? 40  GLY   A CA  1 
ATOM   289  C  C   . GLY   A 1 40  ? -33.60379 -22.45975 4.67640   1.000 41.06823  ? 40  GLY   A C   1 
ATOM   290  O  O   . GLY   A 1 40  ? -32.97788 -23.23660 3.94588   1.000 39.80967  ? 40  GLY   A O   1 
ATOM   291  N  N   . ASP   A 1 41  ? -34.19135 -21.34262 4.22807   1.000 36.32440  ? 41  ASP   A N   1 
ATOM   292  C  CA  . ASP   A 1 41  ? -34.20897 -20.94064 2.81623   1.000 39.27692  ? 41  ASP   A CA  1 
ATOM   293  C  C   . ASP   A 1 41  ? -34.95599 -21.96370 1.95618   1.000 34.40162  ? 41  ASP   A C   1 
ATOM   294  O  O   . ASP   A 1 41  ? -34.59138 -22.22041 0.79849   1.000 35.80651  ? 41  ASP   A O   1 
ATOM   295  C  CB  . ASP   A 1 41  ? -32.79791 -20.70187 2.25445   1.000 34.89212  ? 41  ASP   A CB  1 
ATOM   296  C  CG  . ASP   A 1 41  ? -32.20469 -19.34817 2.65286   1.000 46.09432  ? 41  ASP   A CG  1 
ATOM   297  O  OD1 . ASP   A 1 41  ? -32.84107 -18.61121 3.44512   1.000 34.52326  ? 41  ASP   A OD1 1 
ATOM   298  O  OD2 . ASP   A 1 41  ? -31.08908 -19.02604 2.15687   1.000 47.82950  ? 41  ASP   A OD2 1 
ATOM   299  N  N   . LEU   A 1 42  ? -35.99636 -22.57770 2.51512   1.000 36.08125  ? 42  LEU   A N   1 
ATOM   300  C  CA  . LEU   A 1 42  ? -36.89826 -23.38020 1.68721   1.000 35.25004  ? 42  LEU   A CA  1 
ATOM   301  C  C   . LEU   A 1 42  ? -37.50618 -22.53121 0.56383   1.000 41.26728  ? 42  LEU   A C   1 
ATOM   302  O  O   . LEU   A 1 42  ? -37.51317 -22.93988 -0.60467  1.000 36.18390  ? 42  LEU   A O   1 
ATOM   303  C  CB  . LEU   A 1 42  ? -37.98668 -24.00895 2.56231   1.000 40.73847  ? 42  LEU   A CB  1 
ATOM   304  C  CG  . LEU   A 1 42  ? -39.06527 -24.89565 1.91874   1.000 40.42200  ? 42  LEU   A CG  1 
ATOM   305  C  CD1 . LEU   A 1 42  ? -38.41817 -26.06645 1.16632   1.000 33.30538  ? 42  LEU   A CD1 1 
ATOM   306  C  CD2 . LEU   A 1 42  ? -40.04598 -25.41138 2.98349   1.000 30.56892  ? 42  LEU   A CD2 1 
ATOM   307  N  N   . PHE   A 1 43  ? -37.96978 -21.32093 0.88914   1.000 29.95168  ? 43  PHE   A N   1 
ATOM   308  C  CA  . PHE   A 1 43  ? -38.55332 -20.40549 -0.08536  1.000 35.33407  ? 43  PHE   A CA  1 
ATOM   309  C  C   . PHE   A 1 43  ? -37.64315 -19.21015 -0.34212  1.000 44.03086  ? 43  PHE   A C   1 
ATOM   310  O  O   . PHE   A 1 43  ? -36.89773 -18.76570 0.54269   1.000 35.27878  ? 43  PHE   A O   1 
ATOM   311  C  CB  . PHE   A 1 43  ? -39.92091 -19.89226 0.38686   1.000 36.03710  ? 43  PHE   A CB  1 
ATOM   312  C  CG  . PHE   A 1 43  ? -40.92470 -20.98044 0.59562   1.000 36.29560  ? 43  PHE   A CG  1 
ATOM   313  C  CD1 . PHE   A 1 43  ? -41.67590 -21.46730 -0.47047  1.000 37.80740  ? 43  PHE   A CD1 1 
ATOM   314  C  CD2 . PHE   A 1 43  ? -41.09457 -21.54254 1.85836   1.000 34.69720  ? 43  PHE   A CD2 1 
ATOM   315  C  CE1 . PHE   A 1 43  ? -42.60383 -22.49911 -0.27981  1.000 37.85877  ? 43  PHE   A CE1 1 
ATOM   316  C  CE2 . PHE   A 1 43  ? -42.00141 -22.56695 2.06497   1.000 33.88208  ? 43  PHE   A CE2 1 
ATOM   317  C  CZ  . PHE   A 1 43  ? -42.76596 -23.04827 0.99527   1.000 33.79627  ? 43  PHE   A CZ  1 
ATOM   318  N  N   . GLU   A 1 44  ? -37.74541 -18.66645 -1.56267  1.000 35.61721  ? 44  GLU   A N   1 
ATOM   319  C  CA  . GLU   A 1 44  ? -36.96574 -17.48658 -1.92277  1.000 36.10586  ? 44  GLU   A CA  1 
ATOM   320  C  C   . GLU   A 1 44  ? -37.42586 -16.24065 -1.17264  1.000 42.99624  ? 44  GLU   A C   1 
ATOM   321  O  O   . GLU   A 1 44  ? -36.63557 -15.30221 -0.98902  1.000 47.41968  ? 44  GLU   A O   1 
ATOM   322  C  CB  . GLU   A 1 44  ? -37.03315 -17.26092 -3.43840  1.000 52.05497  ? 44  GLU   A CB  1 
ATOM   323  C  CG  . GLU   A 1 44  ? -36.44917 -15.92709 -3.91524  1.000 50.12427  ? 44  GLU   A CG  1 
ATOM   324  C  CD  . GLU   A 1 44  ? -34.92760 -15.93727 -3.96855  1.000 72.99896  ? 44  GLU   A CD  1 
ATOM   325  O  OE1 . GLU   A 1 44  ? -34.31681 -16.88567 -3.42178  1.000 64.71357  ? 44  GLU   A OE1 1 
ATOM   326  O  OE2 . GLU   A 1 44  ? -34.34144 -14.97901 -4.52393  1.000 75.68688  ? 44  GLU   A OE2 1 
ATOM   327  N  N   . ALA   A 1 45  ? -38.68323 -16.21070 -0.73199  1.000 40.76818  ? 45  ALA   A N   1 
ATOM   328  C  CA  . ALA   A 1 45  ? -39.22398 -15.06722 -0.01271  1.000 45.01444  ? 45  ALA   A CA  1 
ATOM   329  C  C   . ALA   A 1 45  ? -40.39508 -15.52400 0.84155   1.000 40.59644  ? 45  ALA   A C   1 
ATOM   330  O  O   . ALA   A 1 45  ? -41.00416 -16.56887 0.59437   1.000 55.55817  ? 45  ALA   A O   1 
ATOM   331  C  CB  . ALA   A 1 45  ? -39.66280 -13.94339 -0.96844  1.000 30.66135  ? 45  ALA   A CB  1 
ATOM   332  N  N   . TRP   A 1 46  ? -40.70109 -14.73274 1.86388   1.000 42.13059  ? 46  TRP   A N   1 
ATOM   333  C  CA  . TRP   A 1 46  ? -41.87026 -15.00899 2.69247   1.000 51.04817  ? 46  TRP   A CA  1 
ATOM   334  C  C   . TRP   A 1 46  ? -42.30430 -13.72000 3.37001   1.000 45.57597  ? 46  TRP   A C   1 
ATOM   335  O  O   . TRP   A 1 46  ? -41.47554 -13.03098 3.97036   1.000 43.34223  ? 46  TRP   A O   1 
ATOM   336  C  CB  . TRP   A 1 46  ? -41.56646 -16.08719 3.72922   1.000 35.78532  ? 46  TRP   A CB  1 
ATOM   337  C  CG  . TRP   A 1 46  ? -42.79412 -16.72613 4.32702   1.000 45.79155  ? 46  TRP   A CG  1 
ATOM   338  C  CD1 . TRP   A 1 46  ? -43.47227 -16.32177 5.44641   1.000 41.24226  ? 46  TRP   A CD1 1 
ATOM   339  C  CD2 . TRP   A 1 46  ? -43.47982 -17.89262 3.84061   1.000 43.09969  ? 46  TRP   A CD2 1 
ATOM   340  N  NE1 . TRP   A 1 46  ? -44.53962 -17.16757 5.68190   1.000 42.33055  ? 46  TRP   A NE1 1 
ATOM   341  C  CE2 . TRP   A 1 46  ? -44.56060 -18.13858 4.71231   1.000 38.44227  ? 46  TRP   A CE2 1 
ATOM   342  C  CE3 . TRP   A 1 46  ? -43.27146 -18.76364 2.75900   1.000 45.96855  ? 46  TRP   A CE3 1 
ATOM   343  C  CZ2 . TRP   A 1 46  ? -45.42765 -19.22103 4.53849   1.000 36.14445  ? 46  TRP   A CZ2 1 
ATOM   344  C  CZ3 . TRP   A 1 46  ? -44.14821 -19.83481 2.58041   1.000 38.45742  ? 46  TRP   A CZ3 1 
ATOM   345  C  CH2 . TRP   A 1 46  ? -45.20246 -20.05473 3.46954   1.000 38.00593  ? 46  TRP   A CH2 1 
ATOM   346  N  N   . ILE   A 1 47  ? -43.58888 -13.38019 3.25118   1.000 48.45026  ? 47  ILE   A N   1 
ATOM   347  C  CA  . ILE   A 1 47  ? -44.11456 -12.16111 3.85276   1.000 42.64999  ? 47  ILE   A CA  1 
ATOM   348  C  C   . ILE   A 1 47  ? -45.24395 -12.45086 4.83056   1.000 49.14346  ? 47  ILE   A C   1 
ATOM   349  O  O   . ILE   A 1 47  ? -45.97471 -11.53786 5.21528   1.000 44.81065  ? 47  ILE   A O   1 
ATOM   350  C  CB  . ILE   A 1 47  ? -44.56151 -11.14655 2.78090   1.000 41.39690  ? 47  ILE   A CB  1 
ATOM   351  C  CG1 . ILE   A 1 47  ? -45.64582 -11.74401 1.88518   1.000 50.19733  ? 47  ILE   A CG1 1 
ATOM   352  C  CG2 . ILE   A 1 47  ? -43.37090 -10.69737 1.94683   1.000 39.97442  ? 47  ILE   A CG2 1 
ATOM   353  C  CD1 . ILE   A 1 47  ? -46.38564 -10.72091 1.05034   1.000 49.27073  ? 47  ILE   A CD1 1 
ATOM   354  N  N   . GLY   A 1 48  ? -45.39407 -13.70235 5.25051   1.000 46.90652  ? 48  GLY   A N   1 
ATOM   355  C  CA  . GLY   A 1 48  ? -46.41580 -14.06677 6.21660   1.000 40.61870  ? 48  GLY   A CA  1 
ATOM   356  C  C   . GLY   A 1 48  ? -47.23024 -15.24715 5.72934   1.000 43.07245  ? 48  GLY   A C   1 
ATOM   357  O  O   . GLY   A 1 48  ? -47.40137 -15.46175 4.52595   1.000 43.78656  ? 48  GLY   A O   1 
ATOM   358  N  N   . ASP   A 1 49  ? -47.76221 -16.01627 6.68294   1.000 37.71295  ? 49  ASP   A N   1 
ATOM   359  C  CA  . ASP   A 1 49  ? -48.47162 -17.24396 6.34711   1.000 38.86886  ? 49  ASP   A CA  1 
ATOM   360  C  C   . ASP   A 1 49  ? -49.84266 -16.99459 5.72622   1.000 50.66046  ? 49  ASP   A C   1 
ATOM   361  O  O   . ASP   A 1 49  ? -50.48042 -17.95975 5.28754   1.000 47.71520  ? 49  ASP   A O   1 
ATOM   362  C  CB  . ASP   A 1 49  ? -48.65152 -18.11543 7.59351   1.000 40.33990  ? 49  ASP   A CB  1 
ATOM   363  C  CG  . ASP   A 1 49  ? -47.33678 -18.58716 8.19537   1.000 38.63488  ? 49  ASP   A CG  1 
ATOM   364  O  OD1 . ASP   A 1 49  ? -46.25864 -18.44362 7.56990   1.000 46.47222  ? 49  ASP   A OD1 1 
ATOM   365  O  OD2 . ASP   A 1 49  ? -47.38744 -19.08000 9.34108   1.000 45.22045  ? 49  ASP   A OD2 1 
ATOM   366  N  N   . ASP   A 1 50  ? -50.33047 -15.74990 5.69574   1.000 37.20938  ? 50  ASP   A N   1 
ATOM   367  C  CA  . ASP   A 1 50  ? -51.61944 -15.47280 5.06583   1.000 37.36063  ? 50  ASP   A CA  1 
ATOM   368  C  C   . ASP   A 1 50  ? -51.48982 -15.18940 3.57491   1.000 44.05941  ? 50  ASP   A C   1 
ATOM   369  O  O   . ASP   A 1 50  ? -52.50222 -14.89622 2.92289   1.000 38.50519  ? 50  ASP   A O   1 
ATOM   370  C  CB  . ASP   A 1 50  ? -52.34257 -14.28374 5.73353   1.000 42.26762  ? 50  ASP   A CB  1 
ATOM   371  C  CG  . ASP   A 1 50  ? -51.41751 -13.09101 6.01004   1.000 57.69265  ? 50  ASP   A CG  1 
ATOM   372  O  OD1 . ASP   A 1 50  ? -50.22645 -13.12167 5.62690   1.000 49.31081  ? 50  ASP   A OD1 1 
ATOM   373  O  OD2 . ASP   A 1 50  ? -51.90344 -12.08318 6.56670   1.000 61.49163  ? 50  ASP   A OD2 1 
ATOM   374  N  N   . ASP   A 1 51  ? -50.27363 -15.23667 3.03547   1.000 37.39647  ? 51  ASP   A N   1 
ATOM   375  C  CA  . ASP   A 1 51  ? -50.05264 -15.07122 1.60490   1.000 42.89491  ? 51  ASP   A CA  1 
ATOM   376  C  C   . ASP   A 1 51  ? -50.76136 -16.18736 0.83500   1.000 50.08268  ? 51  ASP   A C   1 
ATOM   377  O  O   . ASP   A 1 51  ? -50.48540 -17.36979 1.08101   1.000 45.92498  ? 51  ASP   A O   1 
ATOM   378  C  CB  . ASP   A 1 51  ? -48.55220 -15.08349 1.34479   1.000 34.17863  ? 51  ASP   A CB  1 
ATOM   379  C  CG  . ASP   A 1 51  ? -48.17931 -14.71359 -0.08529  1.000 47.19253  ? 51  ASP   A CG  1 
ATOM   380  O  OD1 . ASP   A 1 51  ? -49.07470 -14.62082 -0.95538  1.000 42.16944  ? 51  ASP   A OD1 1 
ATOM   381  O  OD2 . ASP   A 1 51  ? -46.96257 -14.52903 -0.34048  1.000 50.62561  ? 51  ASP   A OD2 1 
ATOM   382  N  N   . PRO   A 1 52  ? -51.65999 -15.86841 -0.09106  1.000 52.81765  ? 52  PRO   A N   1 
ATOM   383  C  CA  . PRO   A 1 52  ? -52.39308 -16.92831 -0.80220  1.000 45.84035  ? 52  PRO   A CA  1 
ATOM   384  C  C   . PRO   A 1 52  ? -51.64257 -17.50390 -1.99917  1.000 48.90015  ? 52  PRO   A C   1 
ATOM   385  O  O   . PRO   A 1 52  ? -52.23804 -18.20739 -2.82720  1.000 40.82003  ? 52  PRO   A O   1 
ATOM   386  C  CB  . PRO   A 1 52  ? -53.67886 -16.21362 -1.24364  1.000 43.82673  ? 52  PRO   A CB  1 
ATOM   387  C  CG  . PRO   A 1 52  ? -53.25458 -14.80189 -1.44852  1.000 39.78952  ? 52  PRO   A CG  1 
ATOM   388  C  CD  . PRO   A 1 52  ? -52.18618 -14.52471 -0.39902  1.000 42.95580  ? 52  PRO   A CD  1 
ATOM   389  N  N   . ASN   A 1 53  ? -50.34909 -17.20293 -2.10451  1.000 38.44665  ? 53  ASN   A N   1 
ATOM   390  C  CA  . ASN   A 1 53  ? -49.49788 -17.74095 -3.15587  1.000 44.92459  ? 53  ASN   A CA  1 
ATOM   391  C  C   . ASN   A 1 53  ? -49.71912 -19.25178 -3.26486  1.000 40.93665  ? 53  ASN   A C   1 
ATOM   392  O  O   . ASN   A 1 53  ? -49.48121 -19.97454 -2.28218  1.000 38.94201  ? 53  ASN   A O   1 
ATOM   393  C  CB  . ASN   A 1 53  ? -48.02895 -17.45583 -2.84283  1.000 38.42995  ? 53  ASN   A CB  1 
ATOM   394  C  CG  . ASN   A 1 53  ? -47.07769 -17.87489 -3.97819  1.000 53.26856  ? 53  ASN   A CG  1 
ATOM   395  O  OD1 . ASN   A 1 53  ? -47.43071 -18.67068 -4.85633  1.000 46.13572  ? 53  ASN   A OD1 1 
ATOM   396  N  ND2 . ASN   A 1 53  ? -45.83539 -17.39642 -3.90738  1.000 41.76484  ? 53  ASN   A ND2 1 
ATOM   397  N  N   . PRO   A 1 54  ? -50.17898 -19.76212 -4.41672  1.000 48.31818  ? 54  PRO   A N   1 
ATOM   398  C  CA  . PRO   A 1 54  ? -50.52479 -21.19499 -4.49018  1.000 46.16474  ? 54  PRO   A CA  1 
ATOM   399  C  C   . PRO   A 1 54  ? -49.34899 -22.10722 -4.21201  1.000 48.26793  ? 54  PRO   A C   1 
ATOM   400  O  O   . PRO   A 1 54  ? -49.53395 -23.18741 -3.62574  1.000 38.28888  ? 54  PRO   A O   1 
ATOM   401  C  CB  . PRO   A 1 54  ? -51.04390 -21.36274 -5.92849  1.000 41.51954  ? 54  PRO   A CB  1 
ATOM   402  C  CG  . PRO   A 1 54  ? -51.50415 -19.98308 -6.33649  1.000 39.30630  ? 54  PRO   A CG  1 
ATOM   403  C  CD  . PRO   A 1 54  ? -50.53042 -19.04270 -5.65710  1.000 47.38121  ? 54  PRO   A CD  1 
ATOM   404  N  N   . LEU   A 1 55  ? -48.14202 -21.69292 -4.60398  1.000 33.95023  ? 55  LEU   A N   1 
ATOM   405  C  CA  . LEU   A 1 55  ? -46.95817 -22.50718 -4.36032  1.000 39.99505  ? 55  LEU   A CA  1 
ATOM   406  C  C   . LEU   A 1 55  ? -46.84167 -22.87288 -2.88899  1.000 41.19632  ? 55  LEU   A C   1 
ATOM   407  O  O   . LEU   A 1 55  ? -46.47066 -24.00162 -2.55106  1.000 41.03713  ? 55  LEU   A O   1 
ATOM   408  C  CB  . LEU   A 1 55  ? -45.70603 -21.76516 -4.83885  1.000 50.66433  ? 55  LEU   A CB  1 
ATOM   409  C  CG  . LEU   A 1 55  ? -44.34876 -22.41557 -4.54866  1.000 58.15144  ? 55  LEU   A CG  1 
ATOM   410  C  CD1 . LEU   A 1 55  ? -44.23007 -23.77532 -5.24066  1.000 47.43832  ? 55  LEU   A CD1 1 
ATOM   411  C  CD2 . LEU   A 1 55  ? -43.21821 -21.49473 -4.97181  1.000 43.10817  ? 55  LEU   A CD2 1 
ATOM   412  N  N   . HIS   A 1 56  ? -47.17708 -21.93923 -1.99772  1.000 42.32127  ? 56  HIS   A N   1 
ATOM   413  C  CA  . HIS   A 1 56  ? -47.13040 -22.24368 -0.57088  1.000 47.06388  ? 56  HIS   A CA  1 
ATOM   414  C  C   . HIS   A 1 56  ? -48.05512 -23.40496 -0.22736  1.000 42.14870  ? 56  HIS   A C   1 
ATOM   415  O  O   . HIS   A 1 56  ? -47.69746 -24.27878 0.57099   1.000 48.76691  ? 56  HIS   A O   1 
ATOM   416  C  CB  . HIS   A 1 56  ? -47.50029 -21.00485 0.24911   1.000 46.76395  ? 56  HIS   A CB  1 
ATOM   417  C  CG  . HIS   A 1 56  ? -46.55552 -19.86089 0.06445   1.000 50.06357  ? 56  HIS   A CG  1 
ATOM   418  N  ND1 . HIS   A 1 56  ? -46.76448 -18.61960 0.62964   1.000 44.36211  ? 56  HIS   A ND1 1 
ATOM   419  C  CD2 . HIS   A 1 56  ? -45.39547 -19.77073 -0.62934  1.000 44.65056  ? 56  HIS   A CD2 1 
ATOM   420  C  CE1 . HIS   A 1 56  ? -45.77067 -17.81565 0.29425   1.000 39.71011  ? 56  HIS   A CE1 1 
ATOM   421  N  NE2 . HIS   A 1 56  ? -44.92751 -18.49044 -0.46860  1.000 48.23470  ? 56  HIS   A NE2 1 
ATOM   422  N  N   . GLN   A 1 57  ? -49.24662 -23.44140 -0.82549  1.000 44.67171  ? 57  GLN   A N   1 
ATOM   423  C  CA  . GLN   A 1 57  ? -50.16366 -24.53041 -0.51801  1.000 44.59186  ? 57  GLN   A CA  1 
ATOM   424  C  C   . GLN   A 1 57  ? -49.67348 -25.84218 -1.11064  1.000 43.00505  ? 57  GLN   A C   1 
ATOM   425  O  O   . GLN   A 1 57  ? -49.71824 -26.88405 -0.44416  1.000 42.40987  ? 57  GLN   A O   1 
ATOM   426  C  CB  . GLN   A 1 57  ? -51.57340 -24.20019 -1.00958  1.000 50.77392  ? 57  GLN   A CB  1 
ATOM   427  C  CG  . GLN   A 1 57  ? -52.28560 -23.18412 -0.12750  1.000 60.45121  ? 57  GLN   A CG  1 
ATOM   428  C  CD  . GLN   A 1 57  ? -51.97781 -23.39027 1.35314   1.000 84.85479  ? 57  GLN   A CD  1 
ATOM   429  O  OE1 . GLN   A 1 57  ? -51.34267 -22.53985 1.99086   1.000 88.07040  ? 57  GLN   A OE1 1 
ATOM   430  N  NE2 . GLN   A 1 57  ? -52.40318 -24.53065 1.90029   1.000 72.32077  ? 57  GLN   A NE2 1 
ATOM   431  N  N   . GLN   A 1 58  ? -49.20646 -25.80847 -2.36191  1.000 40.97879  ? 58  GLN   A N   1 
ATOM   432  C  CA  . GLN   A 1 58  ? -48.66277 -27.00560 -2.99330  1.000 44.74886  ? 58  GLN   A CA  1 
ATOM   433  C  C   . GLN   A 1 58  ? -47.52381 -27.59094 -2.17261  1.000 42.14905  ? 58  GLN   A C   1 
ATOM   434  O  O   . GLN   A 1 58  ? -47.46952 -28.80691 -1.94492  1.000 37.60074  ? 58  GLN   A O   1 
ATOM   435  C  CB  . GLN   A 1 58  ? -48.19043 -26.67428 -4.41055  1.000 43.36808  ? 58  GLN   A CB  1 
ATOM   436  C  CG  . GLN   A 1 58  ? -49.34867 -26.50598 -5.38020  1.000 56.65796  ? 58  GLN   A CG  1 
ATOM   437  C  CD  . GLN   A 1 58  ? -49.01410 -25.60644 -6.55115  1.000 68.02195  ? 58  GLN   A CD  1 
ATOM   438  O  OE1 . GLN   A 1 58  ? -47.86232 -25.20687 -6.73401  1.000 54.65073  ? 58  GLN   A OE1 1 
ATOM   439  N  NE2 . GLN   A 1 58  ? -50.02868 -25.27322 -7.35135  1.000 54.69805  ? 58  GLN   A NE2 1 
ATOM   440  N  N   . ILE   A 1 59  ? -46.60870 -26.73768 -1.71131  1.000 39.45122  ? 59  ILE   A N   1 
ATOM   441  C  CA  . ILE   A 1 59  ? -45.48508 -27.21966 -0.92197  1.000 42.94803  ? 59  ILE   A CA  1 
ATOM   442  C  C   . ILE   A 1 59  ? -45.97152 -27.76256 0.41563   1.000 39.45893  ? 59  ILE   A C   1 
ATOM   443  O  O   . ILE   A 1 59  ? -45.51603 -28.82146 0.87440   1.000 38.82988  ? 59  ILE   A O   1 
ATOM   444  C  CB  . ILE   A 1 59  ? -44.43532 -26.10325 -0.74647  1.000 38.65845  ? 59  ILE   A CB  1 
ATOM   445  C  CG1 . ILE   A 1 59  ? -43.73569 -25.82729 -2.07676  1.000 40.18496  ? 59  ILE   A CG1 1 
ATOM   446  C  CG2 . ILE   A 1 59  ? -43.38686 -26.50936 0.29632   1.000 30.22151  ? 59  ILE   A CG2 1 
ATOM   447  C  CD1 . ILE   A 1 59  ? -43.13298 -27.09087 -2.72119  1.000 33.47675  ? 59  ILE   A CD1 1 
ATOM   448  N  N   . ALA   A 1 60  ? -46.91516 -27.06096 1.05501   1.000 35.23594  ? 60  ALA   A N   1 
ATOM   449  C  CA  . ALA   A 1 60  ? -47.41720 -27.50739 2.35498   1.000 35.09060  ? 60  ALA   A CA  1 
ATOM   450  C  C   . ALA   A 1 60  ? -48.07777 -28.87640 2.25244   1.000 40.04685  ? 60  ALA   A C   1 
ATOM   451  O  O   . ALA   A 1 60  ? -47.89199 -29.73086 3.12864   1.000 41.46789  ? 60  ALA   A O   1 
ATOM   452  C  CB  . ALA   A 1 60  ? -48.40098 -26.49023 2.93206   1.000 29.97151  ? 60  ALA   A CB  1 
ATOM   453  N  N   . SER   A 1 61  ? -48.84897 -29.10948 1.18619   1.000 35.10040  ? 61  SER   A N   1 
ATOM   454  C  CA  . SER   A 1 61  ? -49.51868 -30.39972 1.04478   1.000 40.03378  ? 61  SER   A CA  1 
ATOM   455  C  C   . SER   A 1 61  ? -48.52303 -31.51291 0.73819   1.000 38.40178  ? 61  SER   A C   1 
ATOM   456  O  O   . SER   A 1 61  ? -48.71958 -32.65323 1.17524   1.000 43.46399  ? 61  SER   A O   1 
ATOM   457  C  CB  . SER   A 1 61  ? -50.60449 -30.32402 -0.03707  1.000 32.35891  ? 61  SER   A CB  1 
ATOM   458  N  N   . ALA   A 1 62  ? -47.43049 -31.20591 0.03048   1.000 43.19658  ? 62  ALA   A N   1 
ATOM   459  C  CA  . ALA   A 1 62  ? -46.47598 -32.26299 -0.30066  1.000 48.56350  ? 62  ALA   A CA  1 
ATOM   460  C  C   . ALA   A 1 62  ? -45.67648 -32.68233 0.92235   1.000 35.23231  ? 62  ALA   A C   1 
ATOM   461  O  O   . ALA   A 1 62  ? -45.38697 -33.87201 1.10764   1.000 42.65679  ? 62  ALA   A O   1 
ATOM   462  C  CB  . ALA   A 1 62  ? -45.53895 -31.81734 -1.41466  1.000 32.54909  ? 62  ALA   A CB  1 
ATOM   463  N  N   . ILE   A 1 63  ? -45.32280 -31.72126 1.77258   1.000 40.14144  ? 63  ILE   A N   1 
ATOM   464  C  CA  . ILE   A 1 63  ? -44.62300 -32.05096 3.00658   1.000 44.83572  ? 63  ILE   A CA  1 
ATOM   465  C  C   . ILE   A 1 63  ? -45.55247 -32.79251 3.95380   1.000 39.39066  ? 63  ILE   A C   1 
ATOM   466  O  O   . ILE   A 1 63  ? -45.16773 -33.80104 4.55759   1.000 44.27305  ? 63  ILE   A O   1 
ATOM   467  C  CB  . ILE   A 1 63  ? -44.03514 -30.77342 3.63974   1.000 47.02543  ? 63  ILE   A CB  1 
ATOM   468  C  CG1 . ILE   A 1 63  ? -42.97801 -30.16496 2.70615   1.000 39.81525  ? 63  ILE   A CG1 1 
ATOM   469  C  CG2 . ILE   A 1 63  ? -43.44001 -31.05455 5.03772   1.000 34.15739  ? 63  ILE   A CG2 1 
ATOM   470  C  CD1 . ILE   A 1 63  ? -42.44444 -28.79652 3.17551   1.000 39.66780  ? 63  ILE   A CD1 1 
ATOM   471  N  N   . LYS   A 1 64  ? -46.79526 -32.32216 4.08213   1.000 40.44970  ? 64  LYS   A N   1 
ATOM   472  C  CA  . LYS   A 1 64  ? -47.76041 -32.99578 4.94502   1.000 40.72865  ? 64  LYS   A CA  1 
ATOM   473  C  C   . LYS   A 1 64  ? -47.93778 -34.45613 4.55289   1.000 38.40616  ? 64  LYS   A C   1 
ATOM   474  O  O   . LYS   A 1 64  ? -48.18448 -35.30985 5.41800   1.000 39.12938  ? 64  LYS   A O   1 
ATOM   475  C  CB  . LYS   A 1 64  ? -49.10256 -32.24997 4.90181   1.000 40.97750  ? 64  LYS   A CB  1 
ATOM   476  C  CG  . LYS   A 1 64  ? -50.20554 -32.86680 5.75090   1.000 41.05802  ? 64  LYS   A CG  1 
ATOM   477  C  CD  . LYS   A 1 64  ? -49.91456 -32.71629 7.24140   1.000 51.31158  ? 64  LYS   A CD  1 
ATOM   478  C  CE  . LYS   A 1 64  ? -51.18905 -32.50893 8.03838   1.000 52.73846  ? 64  LYS   A CE  1 
ATOM   479  N  NZ  . LYS   A 1 64  ? -51.63816 -33.77376 8.67901   1.000 63.59866  ? 64  LYS   A NZ  1 
ATOM   480  N  N   . ALA   A 1 65  ? -47.81112 -34.76952 3.26124   1.000 35.23221  ? 65  ALA   A N   1 
ATOM   481  C  CA  . ALA   A 1 65  ? -47.91453 -36.16209 2.83927   1.000 41.33165  ? 65  ALA   A CA  1 
ATOM   482  C  C   . ALA   A 1 65  ? -46.74498 -36.98876 3.36334   1.000 49.98223  ? 65  ALA   A C   1 
ATOM   483  O  O   . ALA   A 1 65  ? -46.91800 -38.15964 3.72879   1.000 41.75257  ? 65  ALA   A O   1 
ATOM   484  C  CB  . ALA   A 1 65  ? -47.99517 -36.24808 1.31630   1.000 45.12898  ? 65  ALA   A CB  1 
ATOM   485  N  N   . VAL   A 1 66  ? -45.54659 -36.40206 3.39345   1.000 40.28169  ? 66  VAL   A N   1 
ATOM   486  C  CA  . VAL   A 1 66  ? -44.39497 -37.08246 3.97819   1.000 43.08529  ? 66  VAL   A CA  1 
ATOM   487  C  C   . VAL   A 1 66  ? -44.60972 -37.28095 5.47214   1.000 42.06081  ? 66  VAL   A C   1 
ATOM   488  O  O   . VAL   A 1 66  ? -44.32786 -38.35211 6.02193   1.000 42.37700  ? 66  VAL   A O   1 
ATOM   489  C  CB  . VAL   A 1 66  ? -43.10560 -36.28075 3.69030   1.000 48.79959  ? 66  VAL   A CB  1 
ATOM   490  C  CG1 . VAL   A 1 66  ? -41.90181 -36.89571 4.40154   1.000 40.25119  ? 66  VAL   A CG1 1 
ATOM   491  C  CG2 . VAL   A 1 66  ? -42.85118 -36.18163 2.18360   1.000 44.73789  ? 66  VAL   A CG2 1 
ATOM   492  N  N   . VAL   A 1 67  ? -45.11555 -36.24763 6.14578   1.000 41.82693  ? 67  VAL   A N   1 
ATOM   493  C  CA  . VAL   A 1 67  ? -45.40148 -36.31951 7.57517   1.000 40.39043  ? 67  VAL   A CA  1 
ATOM   494  C  C   . VAL   A 1 67  ? -46.44854 -37.39590 7.86080   1.000 50.35207  ? 67  VAL   A C   1 
ATOM   495  O  O   . VAL   A 1 67  ? -46.35245 -38.12568 8.85773   1.000 42.76080  ? 67  VAL   A O   1 
ATOM   496  C  CB  . VAL   A 1 67  ? -45.85894 -34.93034 8.07024   1.000 47.89305  ? 67  VAL   A CB  1 
ATOM   497  C  CG1 . VAL   A 1 67  ? -46.40742 -34.98214 9.49757   1.000 35.64296  ? 67  VAL   A CG1 1 
ATOM   498  C  CG2 . VAL   A 1 67  ? -44.73454 -33.88488 7.92144   1.000 32.20342  ? 67  VAL   A CG2 1 
ATOM   499  N  N   . ASP   A 1 68  ? -47.47669 -37.50119 7.00128   1.000 40.63112  ? 68  ASP   A N   1 
ATOM   500  C  CA  . ASP   A 1 68  ? -48.52950 -38.50028 7.19949   1.000 49.50807  ? 68  ASP   A CA  1 
ATOM   501  C  C   . ASP   A 1 68  ? -48.04835 -39.91547 6.89630   1.000 47.52843  ? 68  ASP   A C   1 
ATOM   502  O  O   . ASP   A 1 68  ? -48.66386 -40.87888 7.36247   1.000 47.45727  ? 68  ASP   A O   1 
ATOM   503  C  CB  . ASP   A 1 68  ? -49.75720 -38.19960 6.32287   1.000 38.77038  ? 68  ASP   A CB  1 
ATOM   504  C  CG  . ASP   A 1 68  ? -50.55898 -36.99135 6.80330   1.000 54.61492  ? 68  ASP   A CG  1 
ATOM   505  O  OD1 . ASP   A 1 68  ? -50.47808 -36.63593 8.00264   1.000 50.04301  ? 68  ASP   A OD1 1 
ATOM   506  O  OD2 . ASP   A 1 68  ? -51.27419 -36.39017 5.96719   1.000 50.45482  ? 68  ASP   A OD2 1 
ATOM   507  N  N   . ALA   A 1 69  ? -46.98648 -40.06311 6.10754   1.000 49.68236  ? 69  ALA   A N   1 
ATOM   508  C  CA  . ALA   A 1 69  ? -46.39509 -41.36853 5.85745   1.000 48.21595  ? 69  ALA   A CA  1 
ATOM   509  C  C   . ALA   A 1 69  ? -45.48893 -41.82425 6.99324   1.000 43.16686  ? 69  ALA   A C   1 
ATOM   510  O  O   . ALA   A 1 69  ? -44.85015 -42.87174 6.87275   1.000 46.02906  ? 69  ALA   A O   1 
ATOM   511  C  CB  . ALA   A 1 69  ? -45.61226 -41.34731 4.54223   1.000 45.88769  ? 69  ALA   A CB  1 
ATOM   512  N  N   . GLY   A 1 70  ? -45.39599 -41.05423 8.07295   1.000 48.09346  ? 70  GLY   A N   1 
ATOM   513  C  CA  . GLY   A 1 70  ? -44.63981 -41.44801 9.23912   1.000 45.60381  ? 70  GLY   A CA  1 
ATOM   514  C  C   . GLY   A 1 70  ? -43.26351 -40.83898 9.39329   1.000 42.00149  ? 70  GLY   A C   1 
ATOM   515  O  O   . GLY   A 1 70  ? -42.51680 -41.27796 10.27731  1.000 43.74102  ? 70  GLY   A O   1 
ATOM   516  N  N   . VAL   A 1 71  ? -42.90856 -39.84235 8.58911   1.000 47.57324  ? 71  VAL   A N   1 
ATOM   517  C  CA  . VAL   A 1 71  ? -41.57382 -39.25029 8.59169   1.000 44.00902  ? 71  VAL   A CA  1 
ATOM   518  C  C   . VAL   A 1 71  ? -41.67510 -37.84853 9.19051   1.000 43.19378  ? 71  VAL   A C   1 
ATOM   519  O  O   . VAL   A 1 71  ? -42.17399 -36.92768 8.52772   1.000 36.46104  ? 71  VAL   A O   1 
ATOM   520  C  CB  . VAL   A 1 71  ? -40.96706 -39.20221 7.18293   1.000 47.29020  ? 71  VAL   A CB  1 
ATOM   521  C  CG1 . VAL   A 1 71  ? -39.58021 -38.53539 7.22181   1.000 42.50654  ? 71  VAL   A CG1 1 
ATOM   522  C  CG2 . VAL   A 1 71  ? -40.87665 -40.59715 6.58703   1.000 32.08387  ? 71  VAL   A CG2 1 
ATOM   523  N  N   . PRO   A 1 72  ? -41.19723 -37.62998 10.41721  1.000 43.22250  ? 72  PRO   A N   1 
ATOM   524  C  CA  . PRO   A 1 72  ? -41.28994 -36.29288 11.01983  1.000 48.92590  ? 72  PRO   A CA  1 
ATOM   525  C  C   . PRO   A 1 72  ? -40.40127 -35.27548 10.30797  1.000 54.94366  ? 72  PRO   A C   1 
ATOM   526  O  O   . PRO   A 1 72  ? -39.28823 -35.58186 9.86900   1.000 35.06088  ? 72  PRO   A O   1 
ATOM   527  C  CB  . PRO   A 1 72  ? -40.83663 -36.52173 12.46873  1.000 49.63201  ? 72  PRO   A CB  1 
ATOM   528  C  CG  . PRO   A 1 72  ? -39.99693 -37.76443 12.41272  1.000 39.25220  ? 72  PRO   A CG  1 
ATOM   529  C  CD  . PRO   A 1 72  ? -40.59740 -38.61962 11.32850  1.000 40.78435  ? 72  PRO   A CD  1 
ATOM   530  N  N   . CYS   A 1 73  ? -40.90635 -34.04518 10.21341  1.000 34.08910  ? 73  CYS   A N   1 
ATOM   531  C  CA  . CYS   A 1 73  ? -40.28663 -33.00333 9.41285   1.000 38.03977  ? 73  CYS   A CA  1 
ATOM   532  C  C   . CYS   A 1 73  ? -40.07953 -31.76529 10.27570  1.000 38.82570  ? 73  CYS   A C   1 
ATOM   533  O  O   . CYS   A 1 73  ? -40.99684 -31.33418 10.98466  1.000 40.97510  ? 73  CYS   A O   1 
ATOM   534  C  CB  . CYS   A 1 73  ? -41.14963 -32.67982 8.19086   1.000 46.35038  ? 73  CYS   A CB  1 
ATOM   535  S  SG  . CYS   A 1 73  ? -41.10829 -33.97051 6.90954   1.000 43.59051  ? 73  CYS   A SG  1 
ATOM   536  N  N   . TYR   A 1 74  ? -38.87665 -31.19504 10.19861  1.000 44.27219  ? 74  TYR   A N   1 
ATOM   537  C  CA  . TYR   A 1 74  ? -38.44854 -30.10296 11.06053  1.000 38.66392  ? 74  TYR   A CA  1 
ATOM   538  C  C   . TYR   A 1 74  ? -37.90010 -28.96780 10.21461  1.000 41.20878  ? 74  TYR   A C   1 
ATOM   539  O  O   . TYR   A 1 74  ? -37.29627 -29.19104 9.16274   1.000 38.72791  ? 74  TYR   A O   1 
ATOM   540  C  CB  . TYR   A 1 74  ? -37.36535 -30.55762 12.04499  1.000 38.74627  ? 74  TYR   A CB  1 
ATOM   541  C  CG  . TYR   A 1 74  ? -37.74530 -31.76041 12.87684  1.000 44.54436  ? 74  TYR   A CG  1 
ATOM   542  C  CD1 . TYR   A 1 74  ? -38.41823 -31.60046 14.07949  1.000 46.21476  ? 74  TYR   A CD1 1 
ATOM   543  C  CD2 . TYR   A 1 74  ? -37.42482 -33.05303 12.46396  1.000 42.19324  ? 74  TYR   A CD2 1 
ATOM   544  C  CE1 . TYR   A 1 74  ? -38.77188 -32.68080 14.84515  1.000 44.99978  ? 74  TYR   A CE1 1 
ATOM   545  C  CE2 . TYR   A 1 74  ? -37.76857 -34.15172 13.23596  1.000 41.55901  ? 74  TYR   A CE2 1 
ATOM   546  C  CZ  . TYR   A 1 74  ? -38.44174 -33.95115 14.42414  1.000 42.08123  ? 74  TYR   A CZ  1 
ATOM   547  O  OH  . TYR   A 1 74  ? -38.80425 -35.01324 15.20687  1.000 47.29698  ? 74  TYR   A OH  1 
ATOM   548  N  N   . PHE   A 1 75  ? -38.08238 -27.74533 10.69969  1.000 37.64519  ? 75  PHE   A N   1 
ATOM   549  C  CA  . PHE   A 1 75  ? -37.66794 -26.57222 9.94507   1.000 38.56808  ? 75  PHE   A CA  1 
ATOM   550  C  C   . PHE   A 1 75  ? -36.93333 -25.60064 10.85280  1.000 39.16085  ? 75  PHE   A C   1 
ATOM   551  O  O   . PHE   A 1 75  ? -37.41525 -25.27754 11.94251  1.000 39.93281  ? 75  PHE   A O   1 
ATOM   552  C  CB  . PHE   A 1 75  ? -38.87986 -25.88860 9.30689   1.000 38.88685  ? 75  PHE   A CB  1 
ATOM   553  C  CG  . PHE   A 1 75  ? -38.53641 -24.67611 8.49265   1.000 46.68397  ? 75  PHE   A CG  1 
ATOM   554  C  CD1 . PHE   A 1 75  ? -37.95344 -24.80534 7.24549   1.000 36.67066  ? 75  PHE   A CD1 1 
ATOM   555  C  CD2 . PHE   A 1 75  ? -38.80750 -23.40183 8.97830   1.000 41.13720  ? 75  PHE   A CD2 1 
ATOM   556  C  CE1 . PHE   A 1 75  ? -37.64469 -23.69316 6.49864   1.000 39.53438  ? 75  PHE   A CE1 1 
ATOM   557  C  CE2 . PHE   A 1 75  ? -38.50981 -22.29480 8.23683   1.000 34.14605  ? 75  PHE   A CE2 1 
ATOM   558  C  CZ  . PHE   A 1 75  ? -37.92533 -22.43368 6.99595   1.000 39.12391  ? 75  PHE   A CZ  1 
ATOM   559  N  N   . ILE   A 1 76  ? -35.76405 -25.14892 10.40632  1.000 35.63597  ? 76  ILE   A N   1 
ATOM   560  C  CA  . ILE   A 1 76  ? -35.08180 -23.99804 10.98602  1.000 35.84039  ? 76  ILE   A CA  1 
ATOM   561  C  C   . ILE   A 1 76  ? -35.16423 -22.85915 9.97527   1.000 42.20905  ? 76  ILE   A C   1 
ATOM   562  O  O   . ILE   A 1 76  ? -34.99224 -23.08421 8.77425   1.000 45.47981  ? 76  ILE   A O   1 
ATOM   563  C  CB  . ILE   A 1 76  ? -33.61696 -24.33066 11.34706  1.000 43.54994  ? 76  ILE   A CB  1 
ATOM   564  C  CG1 . ILE   A 1 76  ? -33.57715 -25.28394 12.55460  1.000 35.77051  ? 76  ILE   A CG1 1 
ATOM   565  C  CG2 . ILE   A 1 76  ? -32.78707 -23.03389 11.57153  1.000 39.17223  ? 76  ILE   A CG2 1 
ATOM   566  C  CD1 . ILE   A 1 76  ? -32.18722 -25.62466 13.05375  1.000 41.37421  ? 76  ILE   A CD1 1 
ATOM   567  N  N   . HIS   A 1 77  ? -35.44229 -21.64459 10.45291  1.000 38.16905  ? 77  HIS   A N   1 
ATOM   568  C  CA  . HIS   A 1 77  ? -35.62611 -20.50685 9.55946   1.000 42.84211  ? 77  HIS   A CA  1 
ATOM   569  C  C   . HIS   A 1 77  ? -34.31772 -20.11568 8.88277   1.000 46.35750  ? 77  HIS   A C   1 
ATOM   570  O  O   . HIS   A 1 77  ? -33.25399 -20.11521 9.50575   1.000 39.70417  ? 77  HIS   A O   1 
ATOM   571  C  CB  . HIS   A 1 77  ? -36.14305 -19.28763 10.32461  1.000 36.89848  ? 77  HIS   A CB  1 
ATOM   572  C  CG  . HIS   A 1 77  ? -37.54869 -19.41448 10.80606  1.000 39.86388  ? 77  HIS   A CG  1 
ATOM   573  N  ND1 . HIS   A 1 77  ? -37.86555 -19.97326 12.02271  1.000 41.29714  ? 77  HIS   A ND1 1 
ATOM   574  C  CD2 . HIS   A 1 77  ? -38.72191 -19.03479 10.24488  1.000 42.29833  ? 77  HIS   A CD2 1 
ATOM   575  C  CE1 . HIS   A 1 77  ? -39.17708 -19.94178 12.18771  1.000 51.13414  ? 77  HIS   A CE1 1 
ATOM   576  N  NE2 . HIS   A 1 77  ? -39.71961 -19.37556 11.12401  1.000 46.83969  ? 77  HIS   A NE2 1 
ATOM   577  N  N   . GLY   A 1 78  ? -34.40964 -19.72446 7.61087   1.000 41.53652  ? 78  GLY   A N   1 
ATOM   578  C  CA  . GLY   A 1 78  ? -33.29030 -19.15420 6.89962   1.000 37.13199  ? 78  GLY   A CA  1 
ATOM   579  C  C   . GLY   A 1 78  ? -33.35702 -17.63668 6.91778   1.000 41.63943  ? 78  GLY   A C   1 
ATOM   580  O  O   . GLY   A 1 78  ? -34.24154 -17.02844 7.51573   1.000 41.76708  ? 78  GLY   A O   1 
ATOM   581  N  N   . ASN   A 1 79  ? -32.38478 -17.01930 6.24713   1.000 42.20212  ? 79  ASN   A N   1 
ATOM   582  C  CA  . ASN   A 1 79  ? -32.41802 -15.56525 6.16563   1.000 46.79697  ? 79  ASN   A CA  1 
ATOM   583  C  C   . ASN   A 1 79  ? -33.47523 -15.08017 5.18727   1.000 37.28548  ? 79  ASN   A C   1 
ATOM   584  O  O   . ASN   A 1 79  ? -33.94964 -13.95253 5.32526   1.000 49.15556  ? 79  ASN   A O   1 
ATOM   585  C  CB  . ASN   A 1 79  ? -31.03603 -15.00300 5.79814   1.000 41.75256  ? 79  ASN   A CB  1 
ATOM   586  C  CG  . ASN   A 1 79  ? -30.56563 -15.42072 4.41716   1.000 44.65702  ? 79  ASN   A CG  1 
ATOM   587  O  OD1 . ASN   A 1 79  ? -30.33867 -16.59677 4.15903   1.000 46.25158  ? 79  ASN   A OD1 1 
ATOM   588  N  ND2 . ASN   A 1 79  ? -30.36630 -14.44279 3.53735   1.000 44.51958  ? 79  ASN   A ND2 1 
ATOM   589  N  N   . ARG   A 1 80  ? -33.89485 -15.91628 4.23528   1.000 44.93628  ? 80  ARG   A N   1 
ATOM   590  C  CA  . ARG   A 1 80  ? -34.92712 -15.50756 3.28538   1.000 43.31703  ? 80  ARG   A CA  1 
ATOM   591  C  C   . ARG   A 1 80  ? -36.33996 -15.73953 3.81170   1.000 46.45057  ? 80  ARG   A C   1 
ATOM   592  O  O   . ARG   A 1 80  ? -37.22942 -14.92554 3.54586   1.000 42.84871  ? 80  ARG   A O   1 
ATOM   593  C  CB  . ARG   A 1 80  ? -34.76240 -16.24559 1.95176   1.000 37.31121  ? 80  ARG   A CB  1 
ATOM   594  C  CG  . ARG   A 1 80  ? -33.38584 -16.12683 1.32203   1.000 39.86210  ? 80  ARG   A CG  1 
ATOM   595  C  CD  . ARG   A 1 80  ? -33.05280 -14.69339 0.95266   1.000 40.13923  ? 80  ARG   A CD  1 
ATOM   596  N  NE  . ARG   A 1 80  ? -34.00763 -14.14833 0.00275   1.000 52.89965  ? 80  ARG   A NE  1 
ATOM   597  C  CZ  . ARG   A 1 80  ? -33.84644 -13.01022 -0.65956  1.000 50.77451  ? 80  ARG   A CZ  1 
ATOM   598  N  NH1 . ARG   A 1 80  ? -32.76207 -12.27140 -0.51028  1.000 40.50291  ? 80  ARG   A NH1 1 
ATOM   599  N  NH2 . ARG   A 1 80  ? -34.80892 -12.59525 -1.48177  1.000 53.11107  ? 80  ARG   A NH2 1 
ATOM   600  N  N   . ASP   A 1 81  ? -36.58252 -16.83804 4.54069   1.000 43.31932  ? 81  ASP   A N   1 
ATOM   601  C  CA  . ASP   A 1 81  ? -37.93697 -17.21148 4.94061   1.000 38.08471  ? 81  ASP   A CA  1 
ATOM   602  C  C   . ASP   A 1 81  ? -38.11879 -17.19074 6.46016   1.000 41.65057  ? 81  ASP   A C   1 
ATOM   603  O  O   . ASP   A 1 81  ? -38.84950 -18.00690 7.03013   1.000 39.99880  ? 81  ASP   A O   1 
ATOM   604  C  CB  . ASP   A 1 81  ? -38.32062 -18.57519 4.35466   1.000 39.50377  ? 81  ASP   A CB  1 
ATOM   605  C  CG  . ASP   A 1 81  ? -37.20473 -19.63763 4.50159   1.000 43.85855  ? 81  ASP   A CG  1 
ATOM   606  O  OD1 . ASP   A 1 81  ? -36.24265 -19.44276 5.27920   1.000 40.02938  ? 81  ASP   A OD1 1 
ATOM   607  O  OD2 . ASP   A 1 81  ? -37.29629 -20.68406 3.82357   1.000 43.63799  ? 81  ASP   A OD2 1 
ATOM   608  N  N   . PHE   A 1 82  ? -37.49171 -16.22323 7.13290   1.000 40.22276  ? 82  PHE   A N   1 
ATOM   609  C  CA  . PHE   A 1 82  ? -37.57230 -16.13249 8.58851   1.000 33.69189  ? 82  PHE   A CA  1 
ATOM   610  C  C   . PHE   A 1 82  ? -38.97672 -15.79932 9.09742   1.000 41.74380  ? 82  PHE   A C   1 
ATOM   611  O  O   . PHE   A 1 82  ? -39.20285 -15.84039 10.31305  1.000 42.20397  ? 82  PHE   A O   1 
ATOM   612  C  CB  . PHE   A 1 82  ? -36.55934 -15.09383 9.10573   1.000 33.46430  ? 82  PHE   A CB  1 
ATOM   613  C  CG  . PHE   A 1 82  ? -36.78077 -13.69475 8.56115   1.000 44.78125  ? 82  PHE   A CG  1 
ATOM   614  C  CD1 . PHE   A 1 82  ? -37.62202 -12.79992 9.22047   1.000 41.04692  ? 82  PHE   A CD1 1 
ATOM   615  C  CD2 . PHE   A 1 82  ? -36.14756 -13.27864 7.40377   1.000 41.02006  ? 82  PHE   A CD2 1 
ATOM   616  C  CE1 . PHE   A 1 82  ? -37.84778 -11.52886 8.72321   1.000 42.68128  ? 82  PHE   A CE1 1 
ATOM   617  C  CE2 . PHE   A 1 82  ? -36.35747 -12.00491 6.90468   1.000 46.39114  ? 82  PHE   A CE2 1 
ATOM   618  C  CZ  . PHE   A 1 82  ? -37.21721 -11.13009 7.56224   1.000 49.92752  ? 82  PHE   A CZ  1 
ATOM   619  N  N   . LEU   A 1 83  ? -39.92526 -15.46544 8.22482   1.000 38.96273  ? 83  LEU   A N   1 
ATOM   620  C  CA  . LEU   A 1 83  ? -41.28390 -15.18807 8.67981   1.000 46.14294  ? 83  LEU   A CA  1 
ATOM   621  C  C   . LEU   A 1 83  ? -42.19861 -16.41857 8.61917   1.000 43.25588  ? 83  LEU   A C   1 
ATOM   622  O  O   . LEU   A 1 83  ? -43.38735 -16.29871 8.92122   1.000 42.79207  ? 83  LEU   A O   1 
ATOM   623  C  CB  . LEU   A 1 83  ? -41.90062 -14.03873 7.86810   1.000 40.11458  ? 83  LEU   A CB  1 
ATOM   624  C  CG  . LEU   A 1 83  ? -41.41514 -12.59837 8.09851   1.000 46.76452  ? 83  LEU   A CG  1 
ATOM   625  C  CD1 . LEU   A 1 83  ? -42.24026 -11.61358 7.27958   1.000 41.08598  ? 83  LEU   A CD1 1 
ATOM   626  C  CD2 . LEU   A 1 83  ? -41.42426 -12.20162 9.57950   1.000 44.52297  ? 83  LEU   A CD2 1 
ATOM   627  N  N   . VAL   A 1 84  ? -41.68609 -17.59659 8.25172   1.000 39.04767  ? 84  VAL   A N   1 
ATOM   628  C  CA  . VAL   A 1 84  ? -42.53404 -18.79010 8.27150   1.000 42.71229  ? 84  VAL   A CA  1 
ATOM   629  C  C   . VAL   A 1 84  ? -43.02609 -19.02294 9.69610   1.000 47.35301  ? 84  VAL   A C   1 
ATOM   630  O  O   . VAL   A 1 84  ? -42.23061 -19.07483 10.64260  1.000 48.00616  ? 84  VAL   A O   1 
ATOM   631  C  CB  . VAL   A 1 84  ? -41.77651 -20.01141 7.72892   1.000 39.92191  ? 84  VAL   A CB  1 
ATOM   632  C  CG1 . VAL   A 1 84  ? -42.61493 -21.27580 7.90268   1.000 35.01537  ? 84  VAL   A CG1 1 
ATOM   633  C  CG2 . VAL   A 1 84  ? -41.40945 -19.81284 6.25857   1.000 33.62589  ? 84  VAL   A CG2 1 
ATOM   634  N  N   . GLY   A 1 85  ? -44.34536 -19.13150 9.86134   1.000 42.54276  ? 85  GLY   A N   1 
ATOM   635  C  CA  . GLY   A 1 85  ? -44.93257 -19.18366 11.18987  1.000 36.99459  ? 85  GLY   A CA  1 
ATOM   636  C  C   . GLY   A 1 85  ? -45.68254 -20.46280 11.52832  1.000 48.13831  ? 85  GLY   A C   1 
ATOM   637  O  O   . GLY   A 1 85  ? -45.57477 -21.47731 10.82751  1.000 41.69429  ? 85  GLY   A O   1 
ATOM   638  N  N   . GLN   A 1 86  ? -46.44902 -20.42593 12.61857  1.000 42.14806  ? 86  GLN   A N   1 
ATOM   639  C  CA  . GLN   A 1 86  ? -47.10639 -21.62662 13.11580  1.000 44.21844  ? 86  GLN   A CA  1 
ATOM   640  C  C   . GLN   A 1 86  ? -48.33259 -22.00865 12.30073  1.000 49.56917  ? 86  GLN   A C   1 
ATOM   641  O  O   . GLN   A 1 86  ? -48.75262 -23.16380 12.35361  1.000 44.74078  ? 86  GLN   A O   1 
ATOM   642  C  CB  . GLN   A 1 86  ? -47.48655 -21.44628 14.58905  1.000 39.65837  ? 86  GLN   A CB  1 
ATOM   643  C  CG  . GLN   A 1 86  ? -46.30339 -21.61934 15.52670  1.000 61.73059  ? 86  GLN   A CG  1 
ATOM   644  C  CD  . GLN   A 1 86  ? -45.91513 -23.09198 15.72369  1.000 69.40361  ? 86  GLN   A CD  1 
ATOM   645  O  OE1 . GLN   A 1 86  ? -46.63414 -24.00418 15.30286  1.000 84.01115  ? 86  GLN   A OE1 1 
ATOM   646  N  NE2 . GLN   A 1 86  ? -44.76044 -23.32136 16.34374  1.000 72.73372  ? 86  GLN   A NE2 1 
ATOM   647  N  N   . ARG   A 1 87  ? -48.91590 -21.07313 11.55124  1.000 48.95995  ? 87  ARG   A N   1 
ATOM   648  C  CA  . ARG   A 1 87  ? -49.97632 -21.44027 10.61938  1.000 48.67732  ? 87  ARG   A CA  1 
ATOM   649  C  C   . ARG   A 1 87  ? -49.43762 -22.32922 9.50265   1.000 49.98369  ? 87  ARG   A C   1 
ATOM   650  O  O   . ARG   A 1 87  ? -50.02104 -23.37752 9.19738   1.000 44.36767  ? 87  ARG   A O   1 
ATOM   651  C  CB  . ARG   A 1 87  ? -50.63614 -20.18849 10.04472  1.000 40.70470  ? 87  ARG   A CB  1 
ATOM   652  C  CG  . ARG   A 1 87  ? -51.62218 -20.47439 8.92763   1.000 47.98834  ? 87  ARG   A CG  1 
ATOM   653  C  CD  . ARG   A 1 87  ? -52.62198 -19.35712 8.76958   1.000 60.89904  ? 87  ARG   A CD  1 
ATOM   654  N  NE  . ARG   A 1 87  ? -53.48495 -19.55423 7.60932   1.000 73.46610  ? 87  ARG   A NE  1 
ATOM   655  C  CZ  . ARG   A 1 87  ? -54.09203 -18.57509 6.95279   1.000 67.15188  ? 87  ARG   A CZ  1 
ATOM   656  N  NH1 . ARG   A 1 87  ? -53.96811 -17.31209 7.32650   1.000 66.11077  ? 87  ARG   A NH1 1 
ATOM   657  N  NH2 . ARG   A 1 87  ? -54.85623 -18.87218 5.90586   1.000 87.86398  ? 87  ARG   A NH2 1 
ATOM   658  N  N   . PHE   A 1 88  ? -48.32392 -21.92769 8.87555   1.000 44.90806  ? 88  PHE   A N   1 
ATOM   659  C  CA  . PHE   A 1 88  ? -47.72719 -22.78172 7.85062   1.000 41.78612  ? 88  PHE   A CA  1 
ATOM   660  C  C   . PHE   A 1 88  ? -47.23932 -24.09728 8.44704   1.000 44.08464  ? 88  PHE   A C   1 
ATOM   661  O  O   . PHE   A 1 88  ? -47.30790 -25.14235 7.78810   1.000 35.25773  ? 88  PHE   A O   1 
ATOM   662  C  CB  . PHE   A 1 88  ? -46.56888 -22.06727 7.13945   1.000 37.72932  ? 88  PHE   A CB  1 
ATOM   663  C  CG  . PHE   A 1 88  ? -45.94822 -22.89118 6.02941   1.000 43.67917  ? 88  PHE   A CG  1 
ATOM   664  C  CD1 . PHE   A 1 88  ? -46.52755 -22.92096 4.76521   1.000 42.99005  ? 88  PHE   A CD1 1 
ATOM   665  C  CD2 . PHE   A 1 88  ? -44.82168 -23.67743 6.26553   1.000 42.64910  ? 88  PHE   A CD2 1 
ATOM   666  C  CE1 . PHE   A 1 88  ? -45.98200 -23.69688 3.74748   1.000 41.13918  ? 88  PHE   A CE1 1 
ATOM   667  C  CE2 . PHE   A 1 88  ? -44.26484 -24.46190 5.25229   1.000 42.78410  ? 88  PHE   A CE2 1 
ATOM   668  C  CZ  . PHE   A 1 88  ? -44.85362 -24.47500 3.99190   1.000 45.69236  ? 88  PHE   A CZ  1 
ATOM   669  N  N   . ALA   A 1 89  ? -46.73084 -24.06365 9.68078   1.000 39.47785  ? 89  ALA   A N   1 
ATOM   670  C  CA  . ALA   A 1 89  ? -46.29986 -25.29545 10.32559  1.000 43.69189  ? 89  ALA   A CA  1 
ATOM   671  C  C   . ALA   A 1 89  ? -47.45364 -26.27887 10.44592  1.000 39.89058  ? 89  ALA   A C   1 
ATOM   672  O  O   . ALA   A 1 89  ? -47.27487 -27.48228 10.23056  1.000 47.58379  ? 89  ALA   A O   1 
ATOM   673  C  CB  . ALA   A 1 89  ? -45.70431 -24.99591 11.70083  1.000 35.13219  ? 89  ALA   A CB  1 
ATOM   674  N  N   . ARG   A 1 90  ? -48.64865 -25.78531 10.78232  1.000 47.92448  ? 90  ARG   A N   1 
ATOM   675  C  CA  . ARG   A 1 90  ? -49.79787 -26.66913 10.92338  1.000 46.62742  ? 90  ARG   A CA  1 
ATOM   676  C  C   . ARG   A 1 90  ? -50.23837 -27.22229 9.57079   1.000 55.79654  ? 90  ARG   A C   1 
ATOM   677  O  O   . ARG   A 1 90  ? -50.50114 -28.42349 9.44852   1.000 51.18041  ? 90  ARG   A O   1 
ATOM   678  C  CB  . ARG   A 1 90  ? -50.94899 -25.93490 11.61922  1.000 46.95465  ? 90  ARG   A CB  1 
ATOM   679  N  N   . GLN   A 1 91  ? -50.31006 -26.37164 8.53810   1.000 41.91809  ? 91  GLN   A N   1 
ATOM   680  C  CA  . GLN   A 1 91  ? -50.70865 -26.86186 7.21730   1.000 47.31619  ? 91  GLN   A CA  1 
ATOM   681  C  C   . GLN   A 1 91  ? -49.74836 -27.92126 6.67753   1.000 45.51636  ? 91  GLN   A C   1 
ATOM   682  O  O   . GLN   A 1 91  ? -50.15686 -28.78183 5.89313   1.000 44.94817  ? 91  GLN   A O   1 
ATOM   683  C  CB  . GLN   A 1 91  ? -50.81227 -25.70485 6.22041   1.000 47.45211  ? 91  GLN   A CB  1 
ATOM   684  C  CG  . GLN   A 1 91  ? -51.93096 -24.72288 6.51002   1.000 60.59460  ? 91  GLN   A CG  1 
ATOM   685  N  N   . SER   A 1 92  ? -48.47857 -27.88200 7.07173   1.000 37.57823  ? 92  SER   A N   1 
ATOM   686  C  CA  . SER   A 1 92  ? -47.49485 -28.80847 6.52644   1.000 41.43844  ? 92  SER   A CA  1 
ATOM   687  C  C   . SER   A 1 92  ? -47.13885 -29.94673 7.47870   1.000 42.14553  ? 92  SER   A C   1 
ATOM   688  O  O   . SER   A 1 92  ? -46.47560 -30.90047 7.05550   1.000 41.43342  ? 92  SER   A O   1 
ATOM   689  C  CB  . SER   A 1 92  ? -46.21684 -28.05785 6.13659   1.000 39.85790  ? 92  SER   A CB  1 
ATOM   690  O  OG  . SER   A 1 92  ? -45.66983 -27.39556 7.25828   1.000 34.15643  ? 92  SER   A OG  1 
ATOM   691  N  N   . GLY   A 1 93  ? -47.57593 -29.88742 8.73664   1.000 39.47084  ? 93  GLY   A N   1 
ATOM   692  C  CA  . GLY   A 1 93  ? -47.15731 -30.86750 9.71540   1.000 36.73272  ? 93  GLY   A CA  1 
ATOM   693  C  C   . GLY   A 1 93  ? -45.71457 -30.75692 10.13553  1.000 37.76745  ? 93  GLY   A C   1 
ATOM   694  O  O   . GLY   A 1 93  ? -45.20605 -31.65712 10.80698  1.000 45.77059  ? 93  GLY   A O   1 
ATOM   695  N  N   . MET   A 1 94  ? -45.04161 -29.67763 9.76311   1.000 40.60094  ? 94  MET   A N   1 
ATOM   696  C  CA  . MET   A 1 94  ? -43.65190 -29.46581 10.12571  1.000 43.30365  ? 94  MET   A CA  1 
ATOM   697  C  C   . MET   A 1 94  ? -43.53597 -28.85791 11.52181  1.000 46.88643  ? 94  MET   A C   1 
ATOM   698  O  O   . MET   A 1 94  ? -44.39833 -28.09485 11.97263  1.000 43.10034  ? 94  MET   A O   1 
ATOM   699  C  CB  . MET   A 1 94  ? -42.99220 -28.55538 9.09435   1.000 42.84476  ? 94  MET   A CB  1 
ATOM   700  C  CG  . MET   A 1 94  ? -42.22409 -29.28185 8.02406   1.000 54.57280  ? 94  MET   A CG  1 
ATOM   701  S  SD  . MET   A 1 94  ? -40.99212 -28.19854 7.28342   1.000 52.59473  ? 94  MET   A SD  1 
ATOM   702  C  CE  . MET   A 1 94  ? -41.95310 -26.69639 7.11414   1.000 41.23035  ? 94  MET   A CE  1 
ATOM   703  N  N   . ILE   A 1 95  ? -42.45057 -29.19511 12.20829  1.000 37.54537  ? 95  ILE   A N   1 
ATOM   704  C  CA  . ILE   A 1 95  ? -42.16694 -28.63348 13.52220  1.000 47.59965  ? 95  ILE   A CA  1 
ATOM   705  C  C   . ILE   A 1 95  ? -41.13334 -27.52767 13.34233  1.000 44.78880  ? 95  ILE   A C   1 
ATOM   706  O  O   . ILE   A 1 95  ? -40.09682 -27.73201 12.69664  1.000 50.06114  ? 95  ILE   A O   1 
ATOM   707  C  CB  . ILE   A 1 95  ? -41.68775 -29.72091 14.50186  1.000 38.77059  ? 95  ILE   A CB  1 
ATOM   708  C  CG1 . ILE   A 1 95  ? -42.88680 -30.56580 14.95248  1.000 54.89937  ? 95  ILE   A CG1 1 
ATOM   709  C  CG2 . ILE   A 1 95  ? -41.02009 -29.10167 15.72083  1.000 44.94794  ? 95  ILE   A CG2 1 
ATOM   710  C  CD1 . ILE   A 1 95  ? -42.55579 -32.02932 15.23579  1.000 56.11098  ? 95  ILE   A CD1 1 
ATOM   711  N  N   . LEU   A 1 96  ? -41.42698 -26.34572 13.87722  1.000 46.12203  ? 96  LEU   A N   1 
ATOM   712  C  CA  . LEU   A 1 96  ? -40.46553 -25.24890 13.85429  1.000 47.36936  ? 96  LEU   A CA  1 
ATOM   713  C  C   . LEU   A 1 96  ? -39.48421 -25.39222 15.00997  1.000 42.03171  ? 96  LEU   A C   1 
ATOM   714  O  O   . LEU   A 1 96  ? -39.88914 -25.53605 16.16939  1.000 41.21058  ? 96  LEU   A O   1 
ATOM   715  C  CB  . LEU   A 1 96  ? -41.18420 -23.90482 13.94560  1.000 47.59875  ? 96  LEU   A CB  1 
ATOM   716  C  CG  . LEU   A 1 96  ? -42.28610 -23.66300 12.91440  1.000 43.41078  ? 96  LEU   A CG  1 
ATOM   717  C  CD1 . LEU   A 1 96  ? -42.89190 -22.27202 13.09531  1.000 42.55975  ? 96  LEU   A CD1 1 
ATOM   718  C  CD2 . LEU   A 1 96  ? -41.74098 -23.85357 11.51053  1.000 41.45928  ? 96  LEU   A CD2 1 
ATOM   719  N  N   . LEU   A 1 97  ? -38.19606 -25.34415 14.69455  1.000 47.69446  ? 97  LEU   A N   1 
ATOM   720  C  CA  . LEU   A 1 97  ? -37.12936 -25.42545 15.68170  1.000 47.09536  ? 97  LEU   A CA  1 
ATOM   721  C  C   . LEU   A 1 97  ? -36.48663 -24.05542 15.84776  1.000 41.04179  ? 97  LEU   A C   1 
ATOM   722  O  O   . LEU   A 1 97  ? -36.68350 -23.15589 15.03076  1.000 44.93142  ? 97  LEU   A O   1 
ATOM   723  C  CB  . LEU   A 1 97  ? -36.08131 -26.45657 15.25421  1.000 41.14936  ? 97  LEU   A CB  1 
ATOM   724  C  CG  . LEU   A 1 97  ? -36.55988 -27.88367 14.97903  1.000 40.64729  ? 97  LEU   A CG  1 
ATOM   725  C  CD1 . LEU   A 1 97  ? -35.39574 -28.68531 14.44393  1.000 47.82639  ? 97  LEU   A CD1 1 
ATOM   726  C  CD2 . LEU   A 1 97  ? -37.11912 -28.54008 16.24072  1.000 37.37862  ? 97  LEU   A CD2 1 
ATOM   727  N  N   . ALA   A 1 98  ? -35.68893 -23.91027 16.90509  1.000 54.02514  ? 98  ALA   A N   1 
ATOM   728  C  CA  . ALA   A 1 98  ? -34.95391 -22.67211 17.12886  1.000 47.97541  ? 98  ALA   A CA  1 
ATOM   729  C  C   . ALA   A 1 98  ? -33.77836 -22.55211 16.15507  1.000 48.76338  ? 98  ALA   A C   1 
ATOM   730  O  O   . ALA   A 1 98  ? -33.46311 -23.46847 15.39225  1.000 48.49607  ? 98  ALA   A O   1 
ATOM   731  C  CB  . ALA   A 1 98  ? -34.45606 -22.59769 18.57022  1.000 45.29766  ? 98  ALA   A CB  1 
ATOM   732  N  N   . GLU   A 1 99  ? -33.11275 -21.39657 16.19397  1.000 49.30827  ? 99  GLU   A N   1 
ATOM   733  C  CA  . GLU   A 1 99  ? -32.04927 -21.12970 15.23035  1.000 51.67216  ? 99  GLU   A CA  1 
ATOM   734  C  C   . GLU   A 1 99  ? -30.81149 -21.99187 15.46189  1.000 50.19922  ? 99  GLU   A C   1 
ATOM   735  O  O   . GLU   A 1 99  ? -30.03871 -22.19916 14.51791  1.000 40.33359  ? 99  GLU   A O   1 
ATOM   736  C  CB  . GLU   A 1 99  ? -31.68012 -19.64431 15.24481  1.000 44.82893  ? 99  GLU   A CB  1 
ATOM   737  C  CG  . GLU   A 1 99  ? -30.91867 -19.19500 16.46503  1.000 59.87616  ? 99  GLU   A CG  1 
ATOM   738  C  CD  . GLU   A 1 99  ? -30.51543 -17.72309 16.39406  1.000 70.49753  ? 99  GLU   A CD  1 
ATOM   739  O  OE1 . GLU   A 1 99  ? -29.29874 -17.44026 16.40584  1.000 77.35431  ? 99  GLU   A OE1 1 
ATOM   740  O  OE2 . GLU   A 1 99  ? -31.40509 -16.84724 16.32343  1.000 82.66593  ? 99  GLU   A OE2 1 
ATOM   741  N  N   . GLU   A 1 100 ? -30.61355 -22.50196 16.68055  1.000 45.59504  ? 100 GLU   A N   1 
ATOM   742  C  CA  . GLU   A 1 100 ? -29.59677 -23.50517 16.98029  1.000 47.56684  ? 100 GLU   A CA  1 
ATOM   743  C  C   . GLU   A 1 100 ? -30.25081 -24.68840 17.69132  1.000 50.06612  ? 100 GLU   A C   1 
ATOM   744  O  O   . GLU   A 1 100 ? -30.99746 -24.49608 18.65567  1.000 57.82884  ? 100 GLU   A O   1 
ATOM   745  C  CB  . GLU   A 1 100 ? -28.48734 -22.91245 17.86097  1.000 51.73848  ? 100 GLU   A CB  1 
ATOM   746  C  CG  . GLU   A 1 100 ? -27.45951 -22.08646 17.11530  1.000 65.57578  ? 100 GLU   A CG  1 
ATOM   747  C  CD  . GLU   A 1 100 ? -26.58824 -21.24472 18.04484  1.000 70.31719  ? 100 GLU   A CD  1 
ATOM   748  O  OE1 . GLU   A 1 100 ? -26.42274 -21.61362 19.23015  1.000 65.85356  ? 100 GLU   A OE1 1 
ATOM   749  O  OE2 . GLU   A 1 100 ? -26.06469 -20.20961 17.58182  1.000 61.08671  ? 100 GLU   A OE2 1 
ATOM   750  N  N   . GLU   A 1 101 ? -29.97796 -25.90670 17.22166  1.000 45.46917  ? 101 GLU   A N   1 
ATOM   751  C  CA  . GLU   A 1 101 ? -30.46467 -27.12043 17.87241  1.000 42.09516  ? 101 GLU   A CA  1 
ATOM   752  C  C   . GLU   A 1 101 ? -29.35468 -28.15610 17.89643  1.000 43.12465  ? 101 GLU   A C   1 
ATOM   753  O  O   . GLU   A 1 101 ? -28.50513 -28.19232 17.00212  1.000 61.04676  ? 101 GLU   A O   1 
ATOM   754  C  CB  . GLU   A 1 101 ? -31.69191 -27.72082 17.16298  1.000 46.95865  ? 101 GLU   A CB  1 
ATOM   755  C  CG  . GLU   A 1 101 ? -32.94966 -26.86941 17.26675  1.000 56.84195  ? 101 GLU   A CG  1 
ATOM   756  C  CD  . GLU   A 1 101 ? -33.66373 -26.98573 18.61190  1.000 57.16253  ? 101 GLU   A CD  1 
ATOM   757  O  OE1 . GLU   A 1 101 ? -33.09213 -27.55440 19.56690  1.000 83.59548  ? 101 GLU   A OE1 1 
ATOM   758  O  OE2 . GLU   A 1 101 ? -34.79749 -26.47129 18.71986  1.000 82.02420  ? 101 GLU   A OE2 1 
ATOM   759  N  N   . ARG   A 1 102 ? -29.37050 -29.00326 18.92467  1.000 52.41314  ? 102 ARG   A N   1 
ATOM   760  C  CA  . ARG   A 1 102 ? -28.42699 -30.11013 19.05597  1.000 51.72551  ? 102 ARG   A CA  1 
ATOM   761  C  C   . ARG   A 1 102 ? -29.20037 -31.42223 19.01167  1.000 49.56594  ? 102 ARG   A C   1 
ATOM   762  O  O   . ARG   A 1 102 ? -30.18134 -31.59741 19.74146  1.000 53.44406  ? 102 ARG   A O   1 
ATOM   763  C  CB  . ARG   A 1 102 ? -27.61451 -30.00359 20.35535  1.000 57.23215  ? 102 ARG   A CB  1 
ATOM   764  C  CG  . ARG   A 1 102 ? -26.72317 -31.20402 20.65006  1.000 74.20158  ? 102 ARG   A CG  1 
ATOM   765  C  CD  . ARG   A 1 102 ? -26.04769 -31.09319 22.01079  1.000 64.74964  ? 102 ARG   A CD  1 
ATOM   766  N  NE  . ARG   A 1 102 ? -26.10839 -29.73295 22.52762  1.000 82.44134  ? 102 ARG   A NE  1 
ATOM   767  C  CZ  . ARG   A 1 102 ? -26.84865 -29.35362 23.56189  1.000 97.66989  ? 102 ARG   A CZ  1 
ATOM   768  N  NH1 . ARG   A 1 102 ? -27.60162 -30.21915 24.22736  1.000 84.19039  ? 102 ARG   A NH1 1 
ATOM   769  N  NH2 . ARG   A 1 102 ? -26.84272 -28.07079 23.92927  1.000 92.96081  ? 102 ARG   A NH2 1 
ATOM   770  N  N   . LEU   A 1 103 ? -28.77567 -32.32865 18.13969  1.000 53.55607  ? 103 LEU   A N   1 
ATOM   771  C  CA  . LEU   A 1 103 ? -29.46062 -33.58971 17.91469  1.000 58.88077  ? 103 LEU   A CA  1 
ATOM   772  C  C   . LEU   A 1 103 ? -28.55910 -34.75265 18.29543  1.000 51.37761  ? 103 LEU   A C   1 
ATOM   773  O  O   . LEU   A 1 103 ? -27.33216 -34.64129 18.28782  1.000 60.29980  ? 103 LEU   A O   1 
ATOM   774  C  CB  . LEU   A 1 103 ? -29.88260 -33.74545 16.45206  1.000 44.67487  ? 103 LEU   A CB  1 
ATOM   775  C  CG  . LEU   A 1 103 ? -30.50432 -32.55782 15.74130  1.000 56.07731  ? 103 LEU   A CG  1 
ATOM   776  C  CD1 . LEU   A 1 103 ? -30.52507 -32.84446 14.25024  1.000 44.89098  ? 103 LEU   A CD1 1 
ATOM   777  C  CD2 . LEU   A 1 103 ? -31.92029 -32.30421 16.26591  1.000 45.88951  ? 103 LEU   A CD2 1 
ATOM   778  N  N   . ASP   A 1 104 ? -29.18356 -35.87968 18.62465  1.000 55.84651  ? 104 ASP   A N   1 
ATOM   779  C  CA  . ASP   A 1 104 ? -28.47978 -37.15310 18.75707  1.000 54.10341  ? 104 ASP   A CA  1 
ATOM   780  C  C   . ASP   A 1 104 ? -28.77349 -37.94897 17.49381  1.000 59.07369  ? 104 ASP   A C   1 
ATOM   781  O  O   . ASP   A 1 104 ? -29.88199 -38.45810 17.31158  1.000 61.20363  ? 104 ASP   A O   1 
ATOM   782  C  CB  . ASP   A 1 104 ? -28.90870 -37.91939 20.00381  1.000 68.36778  ? 104 ASP   A CB  1 
ATOM   783  C  CG  . ASP   A 1 104 ? -28.15917 -39.24334 20.16264  1.000 71.77926  ? 104 ASP   A CG  1 
ATOM   784  O  OD1 . ASP   A 1 104 ? -26.91385 -39.21282 20.27538  1.000 68.66423  ? 104 ASP   A OD1 1 
ATOM   785  O  OD2 . ASP   A 1 104 ? -28.81262 -40.31494 20.16256  1.000 84.15146  ? 104 ASP   A OD2 1 
ATOM   786  N  N   . LEU   A 1 105 ? -27.78013 -38.04896 16.61694  1.000 51.78574  ? 105 LEU   A N   1 
ATOM   787  C  CA  . LEU   A 1 105 ? -27.91059 -38.81111 15.37803  1.000 56.56648  ? 105 LEU   A CA  1 
ATOM   788  C  C   . LEU   A 1 105 ? -27.12419 -40.10737 15.56354  1.000 47.57151  ? 105 LEU   A C   1 
ATOM   789  O  O   . LEU   A 1 105 ? -25.92234 -40.16715 15.32776  1.000 44.46244  ? 105 LEU   A O   1 
ATOM   790  C  CB  . LEU   A 1 105 ? -27.42255 -37.99733 14.18551  1.000 47.86396  ? 105 LEU   A CB  1 
ATOM   791  C  CG  . LEU   A 1 105 ? -28.21555 -36.71907 13.92878  1.000 53.63937  ? 105 LEU   A CG  1 
ATOM   792  C  CD1 . LEU   A 1 105 ? -27.69365 -35.98447 12.70515  1.000 46.62525  ? 105 LEU   A CD1 1 
ATOM   793  C  CD2 . LEU   A 1 105 ? -29.69789 -37.04849 13.77604  1.000 51.43870  ? 105 LEU   A CD2 1 
ATOM   794  N  N   . TYR   A 1 106 ? -27.82185 -41.14670 16.01275  1.000 49.91002  ? 106 TYR   A N   1 
ATOM   795  C  CA  . TYR   A 1 106 ? -27.26284 -42.48713 16.16361  1.000 56.04989  ? 106 TYR   A CA  1 
ATOM   796  C  C   . TYR   A 1 106 ? -26.02209 -42.48110 17.04292  1.000 51.94323  ? 106 TYR   A C   1 
ATOM   797  O  O   . TYR   A 1 106 ? -25.06770 -43.21754 16.79379  1.000 57.15058  ? 106 TYR   A O   1 
ATOM   798  C  CB  . TYR   A 1 106 ? -26.97138 -43.11642 14.79831  1.000 47.93282  ? 106 TYR   A CB  1 
ATOM   799  C  CG  . TYR   A 1 106 ? -28.08676 -42.85479 13.81500  1.000 48.40540  ? 106 TYR   A CG  1 
ATOM   800  C  CD1 . TYR   A 1 106 ? -29.26791 -43.59525 13.85548  1.000 43.20115  ? 106 TYR   A CD1 1 
ATOM   801  C  CD2 . TYR   A 1 106 ? -27.97688 -41.84318 12.87470  1.000 42.58692  ? 106 TYR   A CD2 1 
ATOM   802  C  CE1 . TYR   A 1 106 ? -30.30014 -43.34426 12.96494  1.000 50.56688  ? 106 TYR   A CE1 1 
ATOM   803  C  CE2 . TYR   A 1 106 ? -28.99794 -41.58482 11.97933  1.000 51.48466  ? 106 TYR   A CE2 1 
ATOM   804  C  CZ  . TYR   A 1 106 ? -30.15735 -42.33192 12.03142  1.000 52.11438  ? 106 TYR   A CZ  1 
ATOM   805  O  OH  . TYR   A 1 106 ? -31.16481 -42.06293 11.13922  1.000 47.82865  ? 106 TYR   A OH  1 
ATOM   806  N  N   . GLY   A 1 107 ? -26.02384 -41.63540 18.07069  1.000 60.82764  ? 107 GLY   A N   1 
ATOM   807  C  CA  . GLY   A 1 107 ? -24.96465 -41.59723 19.05164  1.000 63.42370  ? 107 GLY   A CA  1 
ATOM   808  C  C   . GLY   A 1 107 ? -24.04109 -40.40303 18.94522  1.000 66.98981  ? 107 GLY   A C   1 
ATOM   809  O  O   . GLY   A 1 107 ? -23.35922 -40.08096 19.92803  1.000 77.44108  ? 107 GLY   A O   1 
ATOM   810  N  N   . ARG   A 1 108 ? -23.97970 -39.74029 17.79383  1.000 58.61804  ? 108 ARG   A N   1 
ATOM   811  C  CA  . ARG   A 1 108 ? -23.12166 -38.57247 17.64279  1.000 64.73094  ? 108 ARG   A CA  1 
ATOM   812  C  C   . ARG   A 1 108 ? -23.94143 -37.30727 17.85537  1.000 57.15192  ? 108 ARG   A C   1 
ATOM   813  O  O   . ARG   A 1 108 ? -25.05205 -37.17504 17.32552  1.000 53.95698  ? 108 ARG   A O   1 
ATOM   814  C  CB  . ARG   A 1 108 ? -22.41329 -38.55791 16.28275  1.000 74.85481  ? 108 ARG   A CB  1 
ATOM   815  C  CG  . ARG   A 1 108 ? -23.30831 -38.66779 15.07903  1.000 81.48400  ? 108 ARG   A CG  1 
ATOM   816  C  CD  . ARG   A 1 108 ? -22.68370 -38.06519 13.81877  1.000 66.48592  ? 108 ARG   A CD  1 
ATOM   817  N  NE  . ARG   A 1 108 ? -21.75082 -38.97463 13.15968  1.000 70.02813  ? 108 ARG   A NE  1 
ATOM   818  C  CZ  . ARG   A 1 108 ? -22.08997 -40.09407 12.52824  1.000 81.70880  ? 108 ARG   A CZ  1 
ATOM   819  N  NH1 . ARG   A 1 108 ? -23.34167 -40.53433 12.51319  1.000 66.06949  ? 108 ARG   A NH1 1 
ATOM   820  N  NH2 . ARG   A 1 108 ? -21.14448 -40.80336 11.91463  1.000 70.58963  ? 108 ARG   A NH2 1 
ATOM   821  N  N   . GLU   A 1 109 ? -23.40792 -36.40594 18.67645  1.000 54.25675  ? 109 GLU   A N   1 
ATOM   822  C  CA  . GLU   A 1 109 ? -24.04840 -35.12789 18.95074  1.000 62.72997  ? 109 GLU   A CA  1 
ATOM   823  C  C   . GLU   A 1 109 ? -23.75309 -34.16780 17.80171  1.000 51.90220  ? 109 GLU   A C   1 
ATOM   824  O  O   . GLU   A 1 109 ? -22.58743 -33.91682 17.48018  1.000 62.83335  ? 109 GLU   A O   1 
ATOM   825  C  CB  . GLU   A 1 109 ? -23.54921 -34.57036 20.28364  1.000 58.39571  ? 109 GLU   A CB  1 
ATOM   826  N  N   . VAL   A 1 110 ? -24.79920 -33.64514 17.16986  1.000 52.13184  ? 110 VAL   A N   1 
ATOM   827  C  CA  . VAL   A 1 110 ? -24.66195 -32.77818 16.00572  1.000 53.19676  ? 110 VAL   A CA  1 
ATOM   828  C  C   . VAL   A 1 110 ? -25.37695 -31.46922 16.29021  1.000 58.16468  ? 110 VAL   A C   1 
ATOM   829  O  O   . VAL   A 1 110 ? -26.51681 -31.46953 16.76960  1.000 50.39277  ? 110 VAL   A O   1 
ATOM   830  C  CB  . VAL   A 1 110 ? -25.23666 -33.42589 14.73254  1.000 54.35389  ? 110 VAL   A CB  1 
ATOM   831  C  CG1 . VAL   A 1 110 ? -24.86577 -32.58475 13.51277  1.000 48.75936  ? 110 VAL   A CG1 1 
ATOM   832  C  CG2 . VAL   A 1 110 ? -24.75161 -34.85927 14.58889  1.000 49.71989  ? 110 VAL   A CG2 1 
ATOM   833  N  N   . LEU   A 1 111 ? -24.71762 -30.35780 15.98456  1.000 50.31390  ? 111 LEU   A N   1 
ATOM   834  C  CA  . LEU   A 1 111 ? -25.34894 -29.04578 16.03758  1.000 52.68596  ? 111 LEU   A CA  1 
ATOM   835  C  C   . LEU   A 1 111 ? -25.85260 -28.67198 14.64901  1.000 45.45506  ? 111 LEU   A C   1 
ATOM   836  O  O   . LEU   A 1 111 ? -25.12147 -28.81177 13.66231  1.000 56.00405  ? 111 LEU   A O   1 
ATOM   837  C  CB  . LEU   A 1 111 ? -24.36787 -27.99772 16.56106  1.000 54.65628  ? 111 LEU   A CB  1 
ATOM   838  C  CG  . LEU   A 1 111 ? -24.66470 -26.53361 16.25802  1.000 47.13503  ? 111 LEU   A CG  1 
ATOM   839  C  CD1 . LEU   A 1 111 ? -25.71927 -25.98553 17.21110  1.000 49.11076  ? 111 LEU   A CD1 1 
ATOM   840  C  CD2 . LEU   A 1 111 ? -23.36679 -25.75377 16.41582  1.000 60.00637  ? 111 LEU   A CD2 1 
ATOM   841  N  N   . ILE   A 1 112 ? -27.09773 -28.21088 14.56529  1.000 40.88756  ? 112 ILE   A N   1 
ATOM   842  C  CA  . ILE   A 1 112 ? -27.67270 -27.79651 13.29149  1.000 48.98010  ? 112 ILE   A CA  1 
ATOM   843  C  C   . ILE   A 1 112 ? -28.11380 -26.34257 13.38376  1.000 46.93696  ? 112 ILE   A C   1 
ATOM   844  O  O   . ILE   A 1 112 ? -28.57358 -25.88139 14.43687  1.000 44.16698  ? 112 ILE   A O   1 
ATOM   845  C  CB  . ILE   A 1 112 ? -28.84199 -28.70691 12.85272  1.000 44.21047  ? 112 ILE   A CB  1 
ATOM   846  C  CG1 . ILE   A 1 112 ? -30.02041 -28.62459 13.82333  1.000 40.79991  ? 112 ILE   A CG1 1 
ATOM   847  C  CG2 . ILE   A 1 112 ? -28.34784 -30.15108 12.69664  1.000 36.37946  ? 112 ILE   A CG2 1 
ATOM   848  C  CD1 . ILE   A 1 112 ? -31.29532 -29.21056 13.25404  1.000 34.83310  ? 112 ILE   A CD1 1 
ATOM   849  N  N   . MET   A 1 113 ? -27.96474 -25.62456 12.27290  1.000 42.59153  ? 113 MET   A N   1 
ATOM   850  C  CA  . MET   A 1 113 ? -28.38589 -24.23162 12.15789  1.000 41.48402  ? 113 MET   A CA  1 
ATOM   851  C  C   . MET   A 1 113 ? -28.39475 -23.87307 10.67511  1.000 44.46056  ? 113 MET   A C   1 
ATOM   852  O  O   . MET   A 1 113 ? -27.87700 -24.61858 9.83886   1.000 42.60712  ? 113 MET   A O   1 
ATOM   853  C  CB  . MET   A 1 113 ? -27.45816 -23.30179 12.94678  1.000 35.39706  ? 113 MET   A CB  1 
ATOM   854  C  CG  . MET   A 1 113 ? -26.06332 -23.21691 12.36005  1.000 40.40615  ? 113 MET   A CG  1 
ATOM   855  S  SD  . MET   A 1 113 ? -24.96397 -22.11273 13.28443  1.000 63.50302  ? 113 MET   A SD  1 
ATOM   856  C  CE  . MET   A 1 113 ? -24.67376 -23.06360 14.75401  1.000 45.14835  ? 113 MET   A CE  1 
ATOM   857  N  N   . HIS   A 1 114 ? -28.98818 -22.71829 10.35117  1.000 42.57390  ? 114 HIS   A N   1 
ATOM   858  C  CA  . HIS   A 1 114 ? -28.97953 -22.27119 8.95846   1.000 39.78213  ? 114 HIS   A CA  1 
ATOM   859  C  C   . HIS   A 1 114 ? -27.57696 -21.86469 8.52098   1.000 45.61450  ? 114 HIS   A C   1 
ATOM   860  O  O   . HIS   A 1 114 ? -27.17626 -22.12295 7.37801   1.000 40.66287  ? 114 HIS   A O   1 
ATOM   861  C  CB  . HIS   A 1 114 ? -29.94922 -21.10397 8.74891   1.000 36.70802  ? 114 HIS   A CB  1 
ATOM   862  C  CG  . HIS   A 1 114 ? -29.99036 -20.61798 7.32878   1.000 41.05551  ? 114 HIS   A CG  1 
ATOM   863  N  ND1 . HIS   A 1 114 ? -30.36490 -21.42923 6.27666   1.000 44.70913  ? 114 HIS   A ND1 1 
ATOM   864  C  CD2 . HIS   A 1 114 ? -29.65854 -19.42442 6.78145   1.000 38.81406  ? 114 HIS   A CD2 1 
ATOM   865  C  CE1 . HIS   A 1 114 ? -30.28754 -20.74830 5.14685   1.000 38.46119  ? 114 HIS   A CE1 1 
ATOM   866  N  NE2 . HIS   A 1 114 ? -29.84960 -19.53305 5.42370   1.000 40.32679  ? 114 HIS   A NE2 1 
ATOM   867  N  N   . GLY   A 1 115 ? -26.82271 -21.21637 9.40965   1.000 43.46337  ? 115 GLY   A N   1 
ATOM   868  C  CA  . GLY   A 1 115 ? -25.46110 -20.81145 9.12904   1.000 41.07717  ? 115 GLY   A CA  1 
ATOM   869  C  C   . GLY   A 1 115 ? -25.26844 -19.32196 8.91043   1.000 50.31107  ? 115 GLY   A C   1 
ATOM   870  O  O   . GLY   A 1 115 ? -24.12090 -18.87249 8.85233   1.000 48.29545  ? 115 GLY   A O   1 
ATOM   871  N  N   . ASP   A 1 116 ? -26.33171 -18.52734 8.79726   1.000 52.52755  ? 116 ASP   A N   1 
ATOM   872  C  CA  . ASP   A 1 116 ? -26.09519 -17.11642 8.51165   1.000 46.41376  ? 116 ASP   A CA  1 
ATOM   873  C  C   . ASP   A 1 116 ? -25.49202 -16.39752 9.71222   1.000 52.84568  ? 116 ASP   A C   1 
ATOM   874  O  O   . ASP   A 1 116 ? -24.74986 -15.42328 9.53419   1.000 55.55640  ? 116 ASP   A O   1 
ATOM   875  C  CB  . ASP   A 1 116 ? -27.38242 -16.42389 8.03191   1.000 51.97776  ? 116 ASP   A CB  1 
ATOM   876  C  CG  . ASP   A 1 116 ? -28.48437 -16.42370 9.07004   1.000 55.06180  ? 116 ASP   A CG  1 
ATOM   877  O  OD1 . ASP   A 1 116 ? -28.74729 -17.49164 9.66791   1.000 53.13353  ? 116 ASP   A OD1 1 
ATOM   878  O  OD2 . ASP   A 1 116 ? -29.08418 -15.34359 9.28806   1.000 54.58583  ? 116 ASP   A OD2 1 
ATOM   879  N  N   . THR   A 1 117 ? -25.75179 -16.88211 10.93281  1.000 49.70190  ? 117 THR   A N   1 
ATOM   880  C  CA  . THR   A 1 117 ? -25.20326 -16.23687 12.12506  1.000 41.50375  ? 117 THR   A CA  1 
ATOM   881  C  C   . THR   A 1 117 ? -23.71346 -16.50075 12.30342  1.000 54.66843  ? 117 THR   A C   1 
ATOM   882  O  O   . THR   A 1 117 ? -23.11757 -15.95685 13.24176  1.000 52.16138  ? 117 THR   A O   1 
ATOM   883  C  CB  . THR   A 1 117 ? -25.93218 -16.71304 13.38200  1.000 48.88117  ? 117 THR   A CB  1 
ATOM   884  O  OG1 . THR   A 1 117 ? -26.05616 -18.14031 13.35546  1.000 55.38521  ? 117 THR   A OG1 1 
ATOM   885  C  CG2 . THR   A 1 117 ? -27.34199 -16.13087 13.42106  1.000 53.16321  ? 117 THR   A CG2 1 
ATOM   886  N  N   . LEU   A 1 118 ? -23.11069 -17.34703 11.46232  1.000 51.74035  ? 118 LEU   A N   1 
ATOM   887  C  CA  . LEU   A 1 118 ? -21.67301 -17.58712 11.48584  1.000 60.05365  ? 118 LEU   A CA  1 
ATOM   888  C  C   . LEU   A 1 118 ? -20.89622 -16.59100 10.63832  1.000 51.83480  ? 118 LEU   A C   1 
ATOM   889  O  O   . LEU   A 1 118 ? -19.65794 -16.61409 10.65051  1.000 56.73254  ? 118 LEU   A O   1 
ATOM   890  C  CB  . LEU   A 1 118 ? -21.37601 -19.00759 11.00369  1.000 63.31190  ? 118 LEU   A CB  1 
ATOM   891  C  CG  . LEU   A 1 118 ? -22.11779 -20.09641 11.77280  1.000 61.16759  ? 118 LEU   A CG  1 
ATOM   892  C  CD1 . LEU   A 1 118 ? -22.02403 -21.45316 11.05458  1.000 40.62315  ? 118 LEU   A CD1 1 
ATOM   893  C  CD2 . LEU   A 1 118 ? -21.52627 -20.16404 13.17731  1.000 47.25751  ? 118 LEU   A CD2 1 
ATOM   894  N  N   . CYS   A 1 119 ? -21.59349 -15.71926 9.91959   1.000 52.25224  ? 119 CYS   A N   1 
ATOM   895  C  CA  . CYS   A 1 119 ? -20.98833 -14.84238 8.92100   1.000 65.68771  ? 119 CYS   A CA  1 
ATOM   896  C  C   . CYS   A 1 119 ? -20.72872 -13.46177 9.52172   1.000 69.89816  ? 119 CYS   A C   1 
ATOM   897  O  O   . CYS   A 1 119 ? -21.20346 -12.43287 9.03562   1.000 72.10402  ? 119 CYS   A O   1 
ATOM   898  C  CB  . CYS   A 1 119 ? -21.89273 -14.75738 7.69370   1.000 54.81762  ? 119 CYS   A CB  1 
ATOM   899  S  SG  . CYS   A 1 119 ? -21.95632 -16.30004 6.71551   1.000 61.57076  ? 119 CYS   A SG  1 
ATOM   900  N  N   . THR   A 1 120 ? -19.94388 -13.46175 10.59762  1.000 53.09967  ? 120 THR   A N   1 
ATOM   901  C  CA  . THR   A 1 120 ? -19.74900 -12.29080 11.44747  1.000 72.03481  ? 120 THR   A CA  1 
ATOM   902  C  C   . THR   A 1 120 ? -18.83458 -11.23464 10.84149  1.000 66.15921  ? 120 THR   A C   1 
ATOM   903  O  O   . THR   A 1 120 ? -18.57543 -10.22083 11.49842  1.000 70.04185  ? 120 THR   A O   1 
ATOM   904  C  CB  . THR   A 1 120 ? -19.19981 -12.72208 12.81172  1.000 63.12186  ? 120 THR   A CB  1 
ATOM   905  O  OG1 . THR   A 1 120 ? -17.90746 -13.31069 12.63705  1.000 60.08902  ? 120 THR   A OG1 1 
ATOM   906  C  CG2 . THR   A 1 120 ? -20.13874 -13.73022 13.47002  1.000 58.66243  ? 120 THR   A CG2 1 
ATOM   907  N  N   . ASP   A 1 121 ? -18.34726 -11.43119 9.61903   1.000 72.82218  ? 121 ASP   A N   1 
ATOM   908  C  CA  . ASP   A 1 121 ? -17.59887 -10.39816 8.91483   1.000 65.70059  ? 121 ASP   A CA  1 
ATOM   909  C  C   . ASP   A 1 121 ? -18.47598 -9.53800  8.01114   1.000 76.74383  ? 121 ASP   A C   1 
ATOM   910  O  O   . ASP   A 1 121 ? -18.03728 -8.45762  7.59843   1.000 75.70267  ? 121 ASP   A O   1 
ATOM   911  C  CB  . ASP   A 1 121 ? -16.48081 -11.03631 8.08245   1.000 60.03606  ? 121 ASP   A CB  1 
ATOM   912  C  CG  . ASP   A 1 121 ? -15.48984 -11.79315 8.93482   1.000 76.99102  ? 121 ASP   A CG  1 
ATOM   913  O  OD1 . ASP   A 1 121 ? -15.07591 -11.23815 9.97203   1.000 73.17335  ? 121 ASP   A OD1 1 
ATOM   914  O  OD2 . ASP   A 1 121 ? -15.15943 -12.95347 8.59406   1.000 78.27159  ? 121 ASP   A OD2 1 
ATOM   915  N  N   . ASP   A 1 122 ? -19.69479 -9.98548  7.69769   1.000 62.68402  ? 122 ASP   A N   1 
ATOM   916  C  CA  . ASP   A 1 122 ? -20.57875 -9.27358  6.77445   1.000 65.88562  ? 122 ASP   A CA  1 
ATOM   917  C  C   . ASP   A 1 122 ? -21.44848 -8.27725  7.54622   1.000 71.79533  ? 122 ASP   A C   1 
ATOM   918  O  O   . ASP   A 1 122 ? -22.67596 -8.36932  7.57715   1.000 64.96929  ? 122 ASP   A O   1 
ATOM   919  C  CB  . ASP   A 1 122 ? -21.43480 -10.26934 5.99631   1.000 66.45066  ? 122 ASP   A CB  1 
ATOM   920  C  CG  . ASP   A 1 122 ? -22.09713 -9.65105  4.77135   1.000 86.81346  ? 122 ASP   A CG  1 
ATOM   921  O  OD1 . ASP   A 1 122 ? -22.10743 -8.40210  4.65394   1.000 75.16768  ? 122 ASP   A OD1 1 
ATOM   922  O  OD2 . ASP   A 1 122 ? -22.64142 -10.42221 3.94596   1.000 88.77708  ? 122 ASP   A OD2 1 
ATOM   923  N  N   . GLN   A 1 123 ? -20.78292 -7.29622  8.16673   1.000 68.48681  ? 123 GLN   A N   1 
ATOM   924  C  CA  . GLN   A 1 123 ? -21.45122 -6.40594  9.11689   1.000 69.54748  ? 123 GLN   A CA  1 
ATOM   925  C  C   . GLN   A 1 123 ? -22.63134 -5.65564  8.51502   1.000 62.10428  ? 123 GLN   A C   1 
ATOM   926  O  O   . GLN   A 1 123 ? -23.52073 -5.22653  9.25852   1.000 64.54652  ? 123 GLN   A O   1 
ATOM   927  C  CB  . GLN   A 1 123 ? -20.44002 -5.42297  9.70550   1.000 75.34333  ? 123 GLN   A CB  1 
ATOM   928  C  CG  . GLN   A 1 123 ? -19.25925 -6.12700  10.35971  1.000 77.60862  ? 123 GLN   A CG  1 
ATOM   929  C  CD  . GLN   A 1 123 ? -18.11319 -5.18860  10.66647  1.000 101.29911 ? 123 GLN   A CD  1 
ATOM   930  O  OE1 . GLN   A 1 123 ? -17.01059 -5.35313  10.14365  1.000 97.63188  ? 123 GLN   A OE1 1 
ATOM   931  N  NE2 . GLN   A 1 123 ? -18.36921 -4.18682  11.50835  1.000 100.19788 ? 123 GLN   A NE2 1 
ATOM   932  N  N   . GLY   A 1 124 ? -22.67569 -5.49210  7.19352   1.000 62.23146  ? 124 GLY   A N   1 
ATOM   933  C  CA  . GLY   A 1 124 ? -23.89777 -5.00685  6.57635   1.000 60.12529  ? 124 GLY   A CA  1 
ATOM   934  C  C   . GLY   A 1 124 ? -25.04496 -5.98704  6.74257   1.000 68.42736  ? 124 GLY   A C   1 
ATOM   935  O  O   . GLY   A 1 124 ? -26.18768 -5.58963  6.99355   1.000 56.14496  ? 124 GLY   A O   1 
ATOM   936  N  N   . TYR   A 1 125 ? -24.75731 -7.28459  6.62242   1.000 62.19967  ? 125 TYR   A N   1 
ATOM   937  C  CA  . TYR   A 1 125 ? -25.82125 -8.26395  6.78735   1.000 60.75782  ? 125 TYR   A CA  1 
ATOM   938  C  C   . TYR   A 1 125 ? -26.30210 -8.31573  8.23315   1.000 59.20932  ? 125 TYR   A C   1 
ATOM   939  O  O   . TYR   A 1 125 ? -27.51225 -8.40118  8.48657   1.000 51.76582  ? 125 TYR   A O   1 
ATOM   940  C  CB  . TYR   A 1 125 ? -25.37539 -9.65271  6.32720   1.000 51.63216  ? 125 TYR   A CB  1 
ATOM   941  C  CG  . TYR   A 1 125 ? -26.39913 -10.69277 6.73816   1.000 61.26279  ? 125 TYR   A CG  1 
ATOM   942  C  CD1 . TYR   A 1 125 ? -27.68416 -10.65927 6.20284   1.000 56.27666  ? 125 TYR   A CD1 1 
ATOM   943  C  CD2 . TYR   A 1 125 ? -26.08833 -11.70370 7.64206   1.000 48.59864  ? 125 TYR   A CD2 1 
ATOM   944  C  CE1 . TYR   A 1 125 ? -28.64893 -11.58167 6.57421   1.000 54.47244  ? 125 TYR   A CE1 1 
ATOM   945  C  CE2 . TYR   A 1 125 ? -27.04264 -12.64347 8.01373   1.000 49.05724  ? 125 TYR   A CE2 1 
ATOM   946  C  CZ  . TYR   A 1 125 ? -28.32002 -12.56859 7.47436   1.000 53.60769  ? 125 TYR   A CZ  1 
ATOM   947  O  OH  . TYR   A 1 125 ? -29.27678 -13.47779 7.82746   1.000 53.10520  ? 125 TYR   A OH  1 
ATOM   948  N  N   . LEU   A 1 126 ? -25.37523 -8.25745  9.19537   1.000 55.13203  ? 126 LEU   A N   1 
ATOM   949  C  CA  . LEU   A 1 126 ? -25.77733 -8.36769  10.59317  1.000 59.01228  ? 126 LEU   A CA  1 
ATOM   950  C  C   . LEU   A 1 126 ? -26.71775 -7.24194  10.99235  1.000 50.83943  ? 126 LEU   A C   1 
ATOM   951  O  O   . LEU   A 1 126 ? -27.68019 -7.46736  11.73455  1.000 54.20854  ? 126 LEU   A O   1 
ATOM   952  C  CB  . LEU   A 1 126 ? -24.56348 -8.39949  11.52224  1.000 58.00186  ? 126 LEU   A CB  1 
ATOM   953  C  CG  . LEU   A 1 126 ? -23.57517 -9.56739  11.49334  1.000 75.44724  ? 126 LEU   A CG  1 
ATOM   954  C  CD1 . LEU   A 1 126 ? -24.30576 -10.86602 11.82082  1.000 60.09232  ? 126 LEU   A CD1 1 
ATOM   955  C  CD2 . LEU   A 1 126 ? -22.77735 -9.69992  10.21952  1.000 72.79905  ? 126 LEU   A CD2 1 
ATOM   956  N  N   . ALA   A 1 127 ? -26.47046 -6.02578  10.50201  1.000 48.61887  ? 127 ALA   A N   1 
ATOM   957  C  CA  . ALA   A 1 127 ? -27.38345 -4.92651  10.80751  1.000 51.23742  ? 127 ALA   A CA  1 
ATOM   958  C  C   . ALA   A 1 127 ? -28.75973 -5.16933  10.20076  1.000 56.41912  ? 127 ALA   A C   1 
ATOM   959  O  O   . ALA   A 1 127 ? -29.78473 -4.97319  10.86717  1.000 51.99997  ? 127 ALA   A O   1 
ATOM   960  C  CB  . ALA   A 1 127 ? -26.81386 -3.59839  10.31117  1.000 50.52354  ? 127 ALA   A CB  1 
ATOM   961  N  N   . PHE   A 1 128 ? -28.80128 -5.58886  8.93458   1.000 48.82442  ? 128 PHE   A N   1 
ATOM   962  C  CA  . PHE   A 1 128 ? -30.07084 -5.94665  8.31632   1.000 48.84392  ? 128 PHE   A CA  1 
ATOM   963  C  C   . PHE   A 1 128 ? -30.76815 -7.05010  9.10474   1.000 53.59233  ? 128 PHE   A C   1 
ATOM   964  O  O   . PHE   A 1 128 ? -31.97066 -6.96348  9.37393   1.000 54.16282  ? 128 PHE   A O   1 
ATOM   965  C  CB  . PHE   A 1 128 ? -29.82975 -6.36478  6.86363   1.000 49.83190  ? 128 PHE   A CB  1 
ATOM   966  C  CG  . PHE   A 1 128 ? -31.06217 -6.83402  6.14697   1.000 69.98350  ? 128 PHE   A CG  1 
ATOM   967  C  CD1 . PHE   A 1 128 ? -31.82861 -5.94241  5.41807   1.000 62.69039  ? 128 PHE   A CD1 1 
ATOM   968  C  CD2 . PHE   A 1 128 ? -31.42679 -8.17410  6.15554   1.000 56.42001  ? 128 PHE   A CD2 1 
ATOM   969  C  CE1 . PHE   A 1 128 ? -32.95583 -6.37160  4.74390   1.000 69.17606  ? 128 PHE   A CE1 1 
ATOM   970  C  CE2 . PHE   A 1 128 ? -32.55185 -8.60434  5.48310   1.000 60.95321  ? 128 PHE   A CE2 1 
ATOM   971  C  CZ  . PHE   A 1 128 ? -33.32158 -7.70317  4.77806   1.000 55.96859  ? 128 PHE   A CZ  1 
ATOM   972  N  N   . ARG   A 1 129 ? -30.02032 -8.07605  9.51991   1.000 53.69308  ? 129 ARG   A N   1 
ATOM   973  C  CA  . ARG   A 1 129 ? -30.63299 -9.20502  10.21444  1.000 53.97096  ? 129 ARG   A CA  1 
ATOM   974  C  C   . ARG   A 1 129 ? -31.24804 -8.77433  11.54244  1.000 58.53729  ? 129 ARG   A C   1 
ATOM   975  O  O   . ARG   A 1 129 ? -32.38773 -9.14473  11.85848  1.000 49.56997  ? 129 ARG   A O   1 
ATOM   976  C  CB  . ARG   A 1 129 ? -29.59939 -10.31272 10.43982  1.000 47.69576  ? 129 ARG   A CB  1 
ATOM   977  C  CG  . ARG   A 1 129 ? -30.19314 -11.56338 11.08090  1.000 56.10716  ? 129 ARG   A CG  1 
ATOM   978  C  CD  . ARG   A 1 129 ? -29.11925 -12.55136 11.50004  1.000 54.76387  ? 129 ARG   A CD  1 
ATOM   979  N  NE  . ARG   A 1 129 ? -29.67870 -13.86176 11.80176  1.000 50.26752  ? 129 ARG   A NE  1 
ATOM   980  C  CZ  . ARG   A 1 129 ? -30.31426 -14.17757 12.92337  1.000 54.45287  ? 129 ARG   A CZ  1 
ATOM   981  N  NH1 . ARG   A 1 129 ? -30.48319 -13.29742 13.89459  1.000 52.41677  ? 129 ARG   A NH1 1 
ATOM   982  N  NH2 . ARG   A 1 129 ? -30.78890 -15.41388 13.07620  1.000 61.12296  ? 129 ARG   A NH2 1 
ATOM   983  N  N   . ALA   A 1 130 ? -30.49713 -8.00621  12.34360  1.000 41.67599  ? 130 ALA   A N   1 
ATOM   984  C  CA  . ALA   A 1 130 ? -31.00914 -7.54717  13.63348  1.000 56.54400  ? 130 ALA   A CA  1 
ATOM   985  C  C   . ALA   A 1 130 ? -32.28628 -6.73182  13.47651  1.000 60.61010  ? 130 ALA   A C   1 
ATOM   986  O  O   . ALA   A 1 130 ? -33.17080 -6.78396  14.33960  1.000 51.91097  ? 130 ALA   A O   1 
ATOM   987  C  CB  . ALA   A 1 130 ? -29.94698 -6.71683  14.35943  1.000 46.05211  ? 130 ALA   A CB  1 
ATOM   988  N  N   . LYS   A 1 131 ? -32.39805 -5.97684  12.38508  1.000 56.10787  ? 131 LYS   A N   1 
ATOM   989  C  CA  . LYS   A 1 131 ? -33.59078 -5.17777  12.13531  1.000 51.61400  ? 131 LYS   A CA  1 
ATOM   990  C  C   . LYS   A 1 131 ? -34.81272 -6.07014  11.93714  1.000 54.17669  ? 131 LYS   A C   1 
ATOM   991  O  O   . LYS   A 1 131 ? -35.76422 -6.03428  12.72725  1.000 51.73042  ? 131 LYS   A O   1 
ATOM   992  C  CB  . LYS   A 1 131 ? -33.34774 -4.29437  10.90686  1.000 66.58180  ? 131 LYS   A CB  1 
ATOM   993  C  CG  . LYS   A 1 131 ? -34.27885 -3.10256  10.72867  1.000 78.76362  ? 131 LYS   A CG  1 
ATOM   994  C  CD  . LYS   A 1 131 ? -34.39641 -2.75695  9.24163   1.000 77.88258  ? 131 LYS   A CD  1 
ATOM   995  C  CE  . LYS   A 1 131 ? -33.17572 -1.98732  8.74844   1.000 97.04200  ? 131 LYS   A CE  1 
ATOM   996  N  NZ  . LYS   A 1 131 ? -32.78739 -2.41521  7.36225   1.000 71.77930  ? 131 LYS   A NZ  1 
ATOM   997  N  N   . VAL   A 1 132 ? -34.78962 -6.90916  10.89221  1.000 45.80197  ? 132 VAL   A N   1 
ATOM   998  C  CA  . VAL   A 1 132 ? -35.96566 -7.68868  10.51227  1.000 46.65376  ? 132 VAL   A CA  1 
ATOM   999  C  C   . VAL   A 1 132 ? -36.21851 -8.86927  11.43542  1.000 55.84293  ? 132 VAL   A C   1 
ATOM   1000 O  O   . VAL   A 1 132 ? -37.18632 -9.60942  11.22243  1.000 48.59751  ? 132 VAL   A O   1 
ATOM   1001 C  CB  . VAL   A 1 132 ? -35.84438 -8.21891  9.06854   1.000 49.26629  ? 132 VAL   A CB  1 
ATOM   1002 C  CG1 . VAL   A 1 132 ? -35.73736 -7.07252  8.08819   1.000 47.55115  ? 132 VAL   A CG1 1 
ATOM   1003 C  CG2 . VAL   A 1 132 ? -34.65890 -9.18388  8.93006   1.000 54.76305  ? 132 VAL   A CG2 1 
ATOM   1004 N  N   . HIS   A 1 133 ? -35.36810 -9.09228  12.43897  1.000 57.17387  ? 133 HIS   A N   1 
ATOM   1005 C  CA  . HIS   A 1 133 ? -35.62399 -10.10676 13.45821  1.000 52.68917  ? 133 HIS   A CA  1 
ATOM   1006 C  C   . HIS   A 1 133 ? -36.06714 -9.49739  14.78327  1.000 58.19048  ? 133 HIS   A C   1 
ATOM   1007 O  O   . HIS   A 1 133 ? -36.23336 -10.23114 15.76560  1.000 51.62485  ? 133 HIS   A O   1 
ATOM   1008 C  CB  . HIS   A 1 133 ? -34.37818 -10.97566 13.67514  1.000 46.70533  ? 133 HIS   A CB  1 
ATOM   1009 C  CG  . HIS   A 1 133 ? -34.19663 -12.04406 12.64058  1.000 51.18321  ? 133 HIS   A CG  1 
ATOM   1010 N  ND1 . HIS   A 1 133 ? -33.63916 -11.79574 11.40360  1.000 52.60337  ? 133 HIS   A ND1 1 
ATOM   1011 C  CD2 . HIS   A 1 133 ? -34.49548 -13.36511 12.66005  1.000 54.18927  ? 133 HIS   A CD2 1 
ATOM   1012 C  CE1 . HIS   A 1 133 ? -33.59846 -12.91794 10.70708  1.000 45.78918  ? 133 HIS   A CE1 1 
ATOM   1013 N  NE2 . HIS   A 1 133 ? -34.11731 -13.88401 11.44477  1.000 49.63583  ? 133 HIS   A NE2 1 
ATOM   1014 N  N   . THR   A 1 134 ? -36.25717 -8.17796  14.82840  1.000 49.02478  ? 134 THR   A N   1 
ATOM   1015 C  CA  . THR   A 1 134 ? -36.78945 -7.51348  16.00497  1.000 48.19007  ? 134 THR   A CA  1 
ATOM   1016 C  C   . THR   A 1 134 ? -38.27909 -7.80165  16.13069  1.000 55.39945  ? 134 THR   A C   1 
ATOM   1017 O  O   . THR   A 1 134 ? -39.03480 -7.52426  15.18825  1.000 53.46430  ? 134 THR   A O   1 
ATOM   1018 C  CB  . THR   A 1 134 ? -36.54052 -6.02005  15.90399  1.000 55.36687  ? 134 THR   A CB  1 
ATOM   1019 O  OG1 . THR   A 1 134 ? -35.13268 -5.78864  15.77008  1.000 52.17039  ? 134 THR   A OG1 1 
ATOM   1020 C  CG2 . THR   A 1 134 ? -37.06742 -5.29474  17.13245  1.000 50.50821  ? 134 THR   A CG2 1 
ATOM   1021 N  N   . PRO   A 1 135 ? -38.74022 -8.36668  17.25057  1.000 55.14426  ? 135 PRO   A N   1 
ATOM   1022 C  CA  . PRO   A 1 135 ? -40.15216 -8.79194  17.32487  1.000 63.80063  ? 135 PRO   A CA  1 
ATOM   1023 C  C   . PRO   A 1 135 ? -41.16372 -7.69687  17.00967  1.000 55.96561  ? 135 PRO   A C   1 
ATOM   1024 O  O   . PRO   A 1 135 ? -42.11945 -7.96011  16.26963  1.000 60.03310  ? 135 PRO   A O   1 
ATOM   1025 C  CB  . PRO   A 1 135 ? -40.29042 -9.30784  18.76398  1.000 59.17650  ? 135 PRO   A CB  1 
ATOM   1026 C  CG  . PRO   A 1 135 ? -38.89763 -9.62604  19.21710  1.000 64.22466  ? 135 PRO   A CG  1 
ATOM   1027 C  CD  . PRO   A 1 135 ? -37.91481 -8.90793  18.34487  1.000 55.57048  ? 135 PRO   A CD  1 
ATOM   1028 N  N   . TRP   A 1 136 ? -40.99230 -6.47538  17.52522  1.000 58.69080  ? 136 TRP   A N   1 
ATOM   1029 C  CA  . TRP   A 1 136 ? -41.98984 -5.44518  17.24310  1.000 54.65839  ? 136 TRP   A CA  1 
ATOM   1030 C  C   . TRP   A 1 136 ? -41.94109 -4.96895  15.79503  1.000 53.93495  ? 136 TRP   A C   1 
ATOM   1031 O  O   . TRP   A 1 136 ? -42.95764 -4.49181  15.27802  1.000 54.75688  ? 136 TRP   A O   1 
ATOM   1032 C  CB  . TRP   A 1 136 ? -41.84976 -4.26085  18.21415  1.000 49.16965  ? 136 TRP   A CB  1 
ATOM   1033 C  CG  . TRP   A 1 136 ? -40.64557 -3.38724  18.04312  1.000 55.73288  ? 136 TRP   A CG  1 
ATOM   1034 C  CD1 . TRP   A 1 136 ? -39.47654 -3.45042  18.75752  1.000 65.84911  ? 136 TRP   A CD1 1 
ATOM   1035 C  CD2 . TRP   A 1 136 ? -40.49591 -2.29036  17.12989  1.000 56.04402  ? 136 TRP   A CD2 1 
ATOM   1036 N  NE1 . TRP   A 1 136 ? -38.60818 -2.46750  18.33606  1.000 47.18322  ? 136 TRP   A NE1 1 
ATOM   1037 C  CE2 . TRP   A 1 136 ? -39.20606 -1.74768  17.33395  1.000 57.13218  ? 136 TRP   A CE2 1 
ATOM   1038 C  CE3 . TRP   A 1 136 ? -41.32156 -1.71925  16.15299  1.000 55.24942  ? 136 TRP   A CE3 1 
ATOM   1039 C  CZ2 . TRP   A 1 136 ? -38.72818 -0.65923  16.60033  1.000 60.39361  ? 136 TRP   A CZ2 1 
ATOM   1040 C  CZ3 . TRP   A 1 136 ? -40.84307 -0.63079  15.42446  1.000 51.65454  ? 136 TRP   A CZ3 1 
ATOM   1041 C  CH2 . TRP   A 1 136 ? -39.55675 -0.11910  15.65044  1.000 50.32565  ? 136 TRP   A CH2 1 
ATOM   1042 N  N   . ILE   A 1 137 ? -40.80008 -5.10836  15.12232  1.000 56.05144  ? 137 ILE   A N   1 
ATOM   1043 C  CA  . ILE   A 1 137 ? -40.72463 -4.74811  13.71046  1.000 54.34237  ? 137 ILE   A CA  1 
ATOM   1044 C  C   . ILE   A 1 137 ? -41.38217 -5.81789  12.84606  1.000 53.71448  ? 137 ILE   A C   1 
ATOM   1045 O  O   . ILE   A 1 137 ? -42.00953 -5.50360  11.82936  1.000 50.81942  ? 137 ILE   A O   1 
ATOM   1046 C  CB  . ILE   A 1 137 ? -39.25816 -4.49901  13.30420  1.000 49.97566  ? 137 ILE   A CB  1 
ATOM   1047 C  CG1 . ILE   A 1 137 ? -38.69266 -3.31122  14.09337  1.000 51.88576  ? 137 ILE   A CG1 1 
ATOM   1048 C  CG2 . ILE   A 1 137 ? -39.14410 -4.29408  11.79147  1.000 41.31335  ? 137 ILE   A CG2 1 
ATOM   1049 C  CD1 . ILE   A 1 137 ? -37.35087 -2.81727  13.61450  1.000 50.95433  ? 137 ILE   A CD1 1 
ATOM   1050 N  N   . GLN   A 1 138 ? -41.24559 -7.09490  13.22696  1.000 44.40224  ? 138 GLN   A N   1 
ATOM   1051 C  CA  . GLN   A 1 138 ? -41.94161 -8.16309  12.51300  1.000 45.12232  ? 138 GLN   A CA  1 
ATOM   1052 C  C   . GLN   A 1 138 ? -43.44991 -8.03786  12.66897  1.000 42.40592  ? 138 GLN   A C   1 
ATOM   1053 O  O   . GLN   A 1 138 ? -44.19208 -8.14939  11.68561  1.000 56.35455  ? 138 GLN   A O   1 
ATOM   1054 C  CB  . GLN   A 1 138 ? -41.47059 -9.53669  13.00614  1.000 48.22358  ? 138 GLN   A CB  1 
ATOM   1055 C  CG  . GLN   A 1 138 ? -40.00791 -9.84080  12.73164  1.000 49.01192  ? 138 GLN   A CG  1 
ATOM   1056 C  CD  . GLN   A 1 138 ? -39.65689 -11.27273 13.05792  1.000 54.41119  ? 138 GLN   A CD  1 
ATOM   1057 O  OE1 . GLN   A 1 138 ? -40.25919 -11.86684 13.94679  1.000 66.42276  ? 138 GLN   A OE1 1 
ATOM   1058 N  NE2 . GLN   A 1 138 ? -38.69703 -11.84279 12.33225  1.000 48.18875  ? 138 GLN   A NE2 1 
ATOM   1059 N  N   . ARG   A 1 139 ? -43.92764 -7.82226  13.90207  1.000 45.70847  ? 139 ARG   A N   1 
ATOM   1060 C  CA  . ARG   A 1 139 ? -45.37116 -7.74416  14.13276  1.000 51.84470  ? 139 ARG   A CA  1 
ATOM   1061 C  C   . ARG   A 1 139 ? -45.98397 -6.56811  13.38998  1.000 45.93839  ? 139 ARG   A C   1 
ATOM   1062 O  O   . ARG   A 1 139 ? -47.09462 -6.67372  12.85529  1.000 56.52260  ? 139 ARG   A O   1 
ATOM   1063 C  CB  . ARG   A 1 139 ? -45.67044 -7.64212  15.62730  1.000 42.75098  ? 139 ARG   A CB  1 
ATOM   1064 C  CG  . ARG   A 1 139 ? -45.37620 -8.91197  16.39953  1.000 63.13272  ? 139 ARG   A CG  1 
ATOM   1065 C  CD  . ARG   A 1 139 ? -45.77194 -8.76371  17.86020  1.000 68.48353  ? 139 ARG   A CD  1 
ATOM   1066 N  NE  . ARG   A 1 139 ? -44.80747 -9.42648  18.73654  1.000 95.31370  ? 139 ARG   A NE  1 
ATOM   1067 C  CZ  . ARG   A 1 139 ? -44.23479 -8.86363  19.79464  1.000 86.53257  ? 139 ARG   A CZ  1 
ATOM   1068 N  NH1 . ARG   A 1 139 ? -44.48512 -7.60738  20.13328  1.000 78.45101  ? 139 ARG   A NH1 1 
ATOM   1069 N  NH2 . ARG   A 1 139 ? -43.38379 -9.57723  20.52783  1.000 73.90699  ? 139 ARG   A NH2 1 
ATOM   1070 N  N   . LEU   A 1 140 ? -45.26955 -5.44162  13.33797  1.000 44.80142  ? 140 LEU   A N   1 
ATOM   1071 C  CA  . LEU   A 1 140 ? -45.75083 -4.28251  12.59239  1.000 44.27168  ? 140 LEU   A CA  1 
ATOM   1072 C  C   . LEU   A 1 140 ? -45.80829 -4.57338  11.09927  1.000 49.21505  ? 140 LEU   A C   1 
ATOM   1073 O  O   . LEU   A 1 140 ? -46.76506 -4.18154  10.41962  1.000 46.07422  ? 140 LEU   A O   1 
ATOM   1074 C  CB  . LEU   A 1 140 ? -44.85162 -3.08062  12.87447  1.000 54.01935  ? 140 LEU   A CB  1 
ATOM   1075 C  CG  . LEU   A 1 140 ? -45.00322 -1.83698  12.00081  1.000 64.18432  ? 140 LEU   A CG  1 
ATOM   1076 C  CD1 . LEU   A 1 140 ? -46.21520 -1.04591  12.43911  1.000 51.93346  ? 140 LEU   A CD1 1 
ATOM   1077 C  CD2 . LEU   A 1 140 ? -43.75098 -0.97076  12.09082  1.000 54.28529  ? 140 LEU   A CD2 1 
ATOM   1078 N  N   . PHE   A 1 141 ? -44.79511 -5.26223  10.57126  1.000 45.76497  ? 141 PHE   A N   1 
ATOM   1079 C  CA  . PHE   A 1 141 ? -44.79210 -5.59524  9.15187   1.000 46.10001  ? 141 PHE   A CA  1 
ATOM   1080 C  C   . PHE   A 1 141 ? -45.92138 -6.55966  8.82515   1.000 45.09650  ? 141 PHE   A C   1 
ATOM   1081 O  O   . PHE   A 1 141 ? -46.66660 -6.35009  7.86199   1.000 52.21281  ? 141 PHE   A O   1 
ATOM   1082 C  CB  . PHE   A 1 141 ? -43.43323 -6.18270  8.75445   1.000 46.10958  ? 141 PHE   A CB  1 
ATOM   1083 C  CG  . PHE   A 1 141 ? -43.36531 -6.67851  7.32916   1.000 41.03075  ? 141 PHE   A CG  1 
ATOM   1084 C  CD1 . PHE   A 1 141 ? -43.15437 -5.79357  6.28158   1.000 40.57200  ? 141 PHE   A CD1 1 
ATOM   1085 C  CD2 . PHE   A 1 141 ? -43.50509 -8.02379  7.04110   1.000 43.55923  ? 141 PHE   A CD2 1 
ATOM   1086 C  CE1 . PHE   A 1 141 ? -43.08417 -6.23955  4.97172   1.000 37.90699  ? 141 PHE   A CE1 1 
ATOM   1087 C  CE2 . PHE   A 1 141 ? -43.43268 -8.48123  5.73061   1.000 41.78691  ? 141 PHE   A CE2 1 
ATOM   1088 C  CZ  . PHE   A 1 141 ? -43.21956 -7.58484  4.69717   1.000 43.76064  ? 141 PHE   A CZ  1 
ATOM   1089 N  N   . LEU   A 1 142 ? -46.08187 -7.61120  9.63793   1.000 44.80466  ? 142 LEU   A N   1 
ATOM   1090 C  CA  . LEU   A 1 142 ? -47.10051 -8.61666  9.36605   1.000 48.91069  ? 142 LEU   A CA  1 
ATOM   1091 C  C   . LEU   A 1 142 ? -48.51209 -8.04881  9.48008   1.000 49.76281  ? 142 LEU   A C   1 
ATOM   1092 O  O   . LEU   A 1 142 ? -49.42478 -8.57461  8.84426   1.000 47.33464  ? 142 LEU   A O   1 
ATOM   1093 C  CB  . LEU   A 1 142 ? -46.91927 -9.81906  10.30919  1.000 43.82022  ? 142 LEU   A CB  1 
ATOM   1094 C  CG  . LEU   A 1 142 ? -45.74100 -10.76381 10.02320  1.000 52.00773  ? 142 LEU   A CG  1 
ATOM   1095 C  CD1 . LEU   A 1 142 ? -45.44154 -11.69810 11.19616  1.000 41.24811  ? 142 LEU   A CD1 1 
ATOM   1096 C  CD2 . LEU   A 1 142 ? -45.99829 -11.58206 8.75787   1.000 40.92565  ? 142 LEU   A CD2 1 
ATOM   1097 N  N   . ALA   A 1 143 ? -48.70712 -6.96853  10.23993  1.000 55.43016  ? 143 ALA   A N   1 
ATOM   1098 C  CA  . ALA   A 1 143 ? -50.02250 -6.35344  10.38560  1.000 52.08347  ? 143 ALA   A CA  1 
ATOM   1099 C  C   . ALA   A 1 143 ? -50.40518 -5.45116  9.21357   1.000 55.54870  ? 143 ALA   A C   1 
ATOM   1100 O  O   . ALA   A 1 143 ? -51.56074 -5.01260  9.14258   1.000 52.95893  ? 143 ALA   A O   1 
ATOM   1101 C  CB  . ALA   A 1 143 ? -50.08570 -5.55230  11.69017  1.000 49.69082  ? 143 ALA   A CB  1 
ATOM   1102 N  N   . LEU   A 1 144 ? -49.48015 -5.16116  8.30107   1.000 45.05824  ? 144 LEU   A N   1 
ATOM   1103 C  CA  . LEU   A 1 144 ? -49.79930 -4.33880  7.14610   1.000 46.36225  ? 144 LEU   A CA  1 
ATOM   1104 C  C   . LEU   A 1 144 ? -50.54683 -5.16758  6.10602   1.000 46.03900  ? 144 LEU   A C   1 
ATOM   1105 O  O   . LEU   A 1 144 ? -50.40337 -6.38977  6.06302   1.000 45.38030  ? 144 LEU   A O   1 
ATOM   1106 C  CB  . LEU   A 1 144 ? -48.52384 -3.77690  6.53187   1.000 38.86643  ? 144 LEU   A CB  1 
ATOM   1107 C  CG  . LEU   A 1 144 ? -47.72383 -2.80010  7.37785   1.000 42.24152  ? 144 LEU   A CG  1 
ATOM   1108 C  CD1 . LEU   A 1 144 ? -46.37221 -2.67316  6.72730   1.000 39.67183  ? 144 LEU   A CD1 1 
ATOM   1109 C  CD2 . LEU   A 1 144 ? -48.41651 -1.43414  7.48151   1.000 35.96561  ? 144 LEU   A CD2 1 
ATOM   1110 N  N   . PRO   A 1 145 ? -51.33872 -4.52702  5.24242   1.000 45.35534  ? 145 PRO   A N   1 
ATOM   1111 C  CA  . PRO   A 1 145 ? -52.06876 -5.29338  4.22575   1.000 49.17170  ? 145 PRO   A CA  1 
ATOM   1112 C  C   . PRO   A 1 145 ? -51.10861 -6.04275  3.31077   1.000 49.76307  ? 145 PRO   A C   1 
ATOM   1113 O  O   . PRO   A 1 145 ? -49.95587 -5.65087  3.11068   1.000 49.73043  ? 145 PRO   A O   1 
ATOM   1114 C  CB  . PRO   A 1 145 ? -52.85697 -4.22410  3.45463   1.000 42.74054  ? 145 PRO   A CB  1 
ATOM   1115 C  CG  . PRO   A 1 145 ? -52.91909 -3.03355  4.37593   1.000 43.60352  ? 145 PRO   A CG  1 
ATOM   1116 C  CD  . PRO   A 1 145 ? -51.63146 -3.08243  5.16236   1.000 45.43749  ? 145 PRO   A CD  1 
ATOM   1117 N  N   . LEU   A 1 146 ? -51.60976 -7.14610  2.75597   1.000 49.12896  ? 146 LEU   A N   1 
ATOM   1118 C  CA  . LEU   A 1 146 ? -50.78993 -8.00054  1.90441   1.000 49.09824  ? 146 LEU   A CA  1 
ATOM   1119 C  C   . LEU   A 1 146 ? -50.17530 -7.22626  0.74357   1.000 51.72776  ? 146 LEU   A C   1 
ATOM   1120 O  O   . LEU   A 1 146 ? -48.98058 -7.38117  0.45245   1.000 46.47587  ? 146 LEU   A O   1 
ATOM   1121 C  CB  . LEU   A 1 146 ? -51.62963 -9.16574  1.38710   1.000 50.76747  ? 146 LEU   A CB  1 
ATOM   1122 C  CG  . LEU   A 1 146 ? -51.58330 -10.44627 2.21733   1.000 69.89382  ? 146 LEU   A CG  1 
ATOM   1123 C  CD1 . LEU   A 1 146 ? -52.63536 -11.43149 1.73357   1.000 57.23497  ? 146 LEU   A CD1 1 
ATOM   1124 C  CD2 . LEU   A 1 146 ? -50.19443 -11.05766 2.10817   1.000 53.31432  ? 146 LEU   A CD2 1 
ATOM   1125 N  N   . PHE   A 1 147 ? -50.96987 -6.39435  0.05812   1.000 48.03955  ? 147 PHE   A N   1 
ATOM   1126 C  CA  . PHE   A 1 147 ? -50.40842 -5.67301  -1.07918  1.000 43.64891  ? 147 PHE   A CA  1 
ATOM   1127 C  C   . PHE   A 1 147 ? -49.33769 -4.69504  -0.62772  1.000 45.96752  ? 147 PHE   A C   1 
ATOM   1128 O  O   . PHE   A 1 147 ? -48.36584 -4.45812  -1.35796  1.000 44.81310  ? 147 PHE   A O   1 
ATOM   1129 C  CB  . PHE   A 1 147 ? -51.50449 -4.97522  -1.89967  1.000 48.13842  ? 147 PHE   A CB  1 
ATOM   1130 C  CG  . PHE   A 1 147 ? -52.09645 -3.73923  -1.26176  1.000 61.90528  ? 147 PHE   A CG  1 
ATOM   1131 C  CD1 . PHE   A 1 147 ? -52.98976 -3.84078  -0.19456  1.000 55.29728  ? 147 PHE   A CD1 1 
ATOM   1132 C  CD2 . PHE   A 1 147 ? -51.80111 -2.47498  -1.76685  1.000 51.23028  ? 147 PHE   A CD2 1 
ATOM   1133 C  CE1 . PHE   A 1 147 ? -53.56104 -2.69675  0.37534   1.000 58.33725  ? 147 PHE   A CE1 1 
ATOM   1134 C  CE2 . PHE   A 1 147 ? -52.37140 -1.32455  -1.20633  1.000 51.16407  ? 147 PHE   A CE2 1 
ATOM   1135 C  CZ  . PHE   A 1 147 ? -53.25226 -1.43827  -0.13053  1.000 47.86414  ? 147 PHE   A CZ  1 
ATOM   1136 N  N   . ILE   A 1 148 ? -49.44831 -4.17598  0.59277   1.000 44.56748  ? 148 ILE   A N   1 
ATOM   1137 C  CA  . ILE   A 1 148 ? -48.39299 -3.29576  1.08036   1.000 55.84191  ? 148 ILE   A CA  1 
ATOM   1138 C  C   . ILE   A 1 148 ? -47.12582 -4.10220  1.33052   1.000 54.35130  ? 148 ILE   A C   1 
ATOM   1139 O  O   . ILE   A 1 148 ? -46.02771 -3.70337  0.92075   1.000 44.69448  ? 148 ILE   A O   1 
ATOM   1140 C  CB  . ILE   A 1 148 ? -48.85030 -2.54169  2.34190   1.000 47.15338  ? 148 ILE   A CB  1 
ATOM   1141 C  CG1 . ILE   A 1 148 ? -50.10935 -1.71850  2.05018   1.000 51.21334  ? 148 ILE   A CG1 1 
ATOM   1142 C  CG2 . ILE   A 1 148 ? -47.73307 -1.62857  2.86200   1.000 46.19238  ? 148 ILE   A CG2 1 
ATOM   1143 C  CD1 . ILE   A 1 148 ? -49.89468 -0.56295  1.11740   1.000 40.15551  ? 148 ILE   A CD1 1 
ATOM   1144 N  N   . ARG   A 1 149 ? -47.26323 -5.26425  1.98282   1.000 47.51495  ? 149 ARG   A N   1 
ATOM   1145 C  CA  . ARG   A 1 149 ? -46.10687 -6.11211  2.25351   1.000 48.96422  ? 149 ARG   A CA  1 
ATOM   1146 C  C   . ARG   A 1 149 ? -45.42254 -6.55680  0.96287   1.000 50.67336  ? 149 ARG   A C   1 
ATOM   1147 O  O   . ARG   A 1 149 ? -44.19075 -6.64773  0.90974   1.000 45.56703  ? 149 ARG   A O   1 
ATOM   1148 C  CB  . ARG   A 1 149 ? -46.53226 -7.32566  3.08244   1.000 47.90042  ? 149 ARG   A CB  1 
ATOM   1149 C  CG  . ARG   A 1 149 ? -46.73342 -7.01772  4.56251   1.000 46.43287  ? 149 ARG   A CG  1 
ATOM   1150 C  CD  . ARG   A 1 149 ? -47.23339 -8.25450  5.29876   1.000 44.53123  ? 149 ARG   A CD  1 
ATOM   1151 N  NE  . ARG   A 1 149 ? -48.69202 -8.34411  5.29613   1.000 42.20475  ? 149 ARG   A NE  1 
ATOM   1152 C  CZ  . ARG   A 1 149 ? -49.36865 -9.48774  5.31858   1.000 51.61455  ? 149 ARG   A CZ  1 
ATOM   1153 N  NH1 . ARG   A 1 149 ? -48.74671 -10.65675 5.32169   1.000 37.34797  ? 149 ARG   A NH1 1 
ATOM   1154 N  NH2 . ARG   A 1 149 ? -50.70274 -9.45898  5.33559   1.000 42.43742  ? 149 ARG   A NH2 1 
ATOM   1155 N  N   . HIS   A 1 150 ? -46.20323 -6.84511  -0.08619  1.000 51.13287  ? 150 HIS   A N   1 
ATOM   1156 C  CA  . HIS   A 1 150 ? -45.61061 -7.22106  -1.36937  1.000 40.59024  ? 150 HIS   A CA  1 
ATOM   1157 C  C   . HIS   A 1 150 ? -44.73842 -6.10190  -1.91806  1.000 53.90397  ? 150 HIS   A C   1 
ATOM   1158 O  O   . HIS   A 1 150 ? -43.60989 -6.34846  -2.36510  1.000 51.83187  ? 150 HIS   A O   1 
ATOM   1159 C  CB  . HIS   A 1 150 ? -46.70432 -7.56352  -2.38206  1.000 51.38378  ? 150 HIS   A CB  1 
ATOM   1160 C  CG  . HIS   A 1 150 ? -47.04369 -9.01812  -2.44835  1.000 44.38318  ? 150 HIS   A CG  1 
ATOM   1161 N  ND1 . HIS   A 1 150 ? -46.14201 -9.97688  -2.85856  1.000 65.79046  ? 150 HIS   A ND1 1 
ATOM   1162 C  CD2 . HIS   A 1 150 ? -48.19669 -9.67660  -2.17541  1.000 52.12259  ? 150 HIS   A CD2 1 
ATOM   1163 C  CE1 . HIS   A 1 150 ? -46.71939 -11.16540 -2.82450  1.000 66.82064  ? 150 HIS   A CE1 1 
ATOM   1164 N  NE2 . HIS   A 1 150 ? -47.96715 -11.01122 -2.41520  1.000 65.89820  ? 150 HIS   A NE2 1 
ATOM   1165 N  N   . ARG   A 1 151 ? -45.24417 -4.85873  -1.88223  1.000 47.47300  ? 151 ARG   A N   1 
ATOM   1166 C  CA  . ARG   A 1 151 ? -44.49096 -3.72119  -2.40540  1.000 47.66404  ? 151 ARG   A CA  1 
ATOM   1167 C  C   . ARG   A 1 151 ? -43.23287 -3.46753  -1.58866  1.000 45.05109  ? 151 ARG   A C   1 
ATOM   1168 O  O   . ARG   A 1 151 ? -42.16377 -3.20983  -2.15440  1.000 48.05667  ? 151 ARG   A O   1 
ATOM   1169 C  CB  . ARG   A 1 151 ? -45.37265 -2.46331  -2.43813  1.000 45.67007  ? 151 ARG   A CB  1 
ATOM   1170 C  CG  . ARG   A 1 151 ? -46.23872 -2.36327  -3.68384  1.000 50.63479  ? 151 ARG   A CG  1 
ATOM   1171 C  CD  . ARG   A 1 151 ? -47.60296 -1.75769  -3.41234  1.000 51.37022  ? 151 ARG   A CD  1 
ATOM   1172 N  NE  . ARG   A 1 151 ? -47.59915 -0.30087  -3.43147  1.000 73.58684  ? 151 ARG   A NE  1 
ATOM   1173 C  CZ  . ARG   A 1 151 ? -48.57147 0.44324   -3.94611  1.000 80.57357  ? 151 ARG   A CZ  1 
ATOM   1174 N  NH1 . ARG   A 1 151 ? -49.65333 -0.10403  -4.47927  1.000 74.67363  ? 151 ARG   A NH1 1 
ATOM   1175 N  NH2 . ARG   A 1 151 ? -48.45645 1.76937   -3.92418  1.000 76.81307  ? 151 ARG   A NH2 1 
ATOM   1176 N  N   . ILE   A 1 152 ? -43.33905 -3.53128  -0.25898  1.000 46.16062  ? 152 ILE   A N   1 
ATOM   1177 C  CA  . ILE   A 1 152 ? -42.16442 -3.35366  0.59245   1.000 52.60166  ? 152 ILE   A CA  1 
ATOM   1178 C  C   . ILE   A 1 152 ? -41.10122 -4.39444  0.26785   1.000 50.97835  ? 152 ILE   A C   1 
ATOM   1179 O  O   . ILE   A 1 152 ? -39.90753 -4.07617  0.15641   1.000 52.35669  ? 152 ILE   A O   1 
ATOM   1180 C  CB  . ILE   A 1 152 ? -42.56583 -3.42440  2.07516   1.000 49.73807  ? 152 ILE   A CB  1 
ATOM   1181 C  CG1 . ILE   A 1 152 ? -43.48115 -2.26023  2.42454   1.000 37.32848  ? 152 ILE   A CG1 1 
ATOM   1182 C  CG2 . ILE   A 1 152 ? -41.30692 -3.45552  2.97018   1.000 41.52055  ? 152 ILE   A CG2 1 
ATOM   1183 C  CD1 . ILE   A 1 152 ? -44.05574 -2.34777  3.81587   1.000 42.69039  ? 152 ILE   A CD1 1 
ATOM   1184 N  N   . ALA   A 1 153 ? -41.51764 -5.65221  0.10908   1.000 39.55747  ? 153 ALA   A N   1 
ATOM   1185 C  CA  . ALA   A 1 153 ? -40.56422 -6.74387  -0.05897  1.000 45.81769  ? 153 ALA   A CA  1 
ATOM   1186 C  C   . ALA   A 1 153 ? -39.87788 -6.67727  -1.41877  1.000 42.38169  ? 153 ALA   A C   1 
ATOM   1187 O  O   . ALA   A 1 153 ? -38.65810 -6.86028  -1.51652  1.000 46.45095  ? 153 ALA   A O   1 
ATOM   1188 C  CB  . ALA   A 1 153 ? -41.28482 -8.08483  0.12876   1.000 36.57369  ? 153 ALA   A CB  1 
ATOM   1189 N  N   . ALA   A 1 154 ? -40.64994 -6.42838  -2.47996  1.000 54.16258  ? 154 ALA   A N   1 
ATOM   1190 C  CA  . ALA   A 1 154 ? -40.06935 -6.27224  -3.81068  1.000 46.35240  ? 154 ALA   A CA  1 
ATOM   1191 C  C   . ALA   A 1 154 ? -39.06625 -5.12650  -3.84644  1.000 54.18378  ? 154 ALA   A C   1 
ATOM   1192 O  O   . ALA   A 1 154 ? -38.02937 -5.21927  -4.51558  1.000 61.35118  ? 154 ALA   A O   1 
ATOM   1193 C  CB  . ALA   A 1 154 ? -41.17454 -6.04029  -4.84125  1.000 50.35589  ? 154 ALA   A CB  1 
ATOM   1194 N  N   . ARG   A 1 155 ? -39.35187 -4.03990  -3.12692  1.000 42.00124  ? 155 ARG   A N   1 
ATOM   1195 C  CA  . ARG   A 1 155 ? -38.41383 -2.92557  -3.08638  1.000 50.20798  ? 155 ARG   A CA  1 
ATOM   1196 C  C   . ARG   A 1 155 ? -37.16251 -3.28715  -2.30119  1.000 51.24141  ? 155 ARG   A C   1 
ATOM   1197 O  O   . ARG   A 1 155 ? -36.05217 -2.90741  -2.69224  1.000 57.85331  ? 155 ARG   A O   1 
ATOM   1198 C  CB  . ARG   A 1 155 ? -39.08423 -1.68718  -2.48902  1.000 49.59477  ? 155 ARG   A CB  1 
ATOM   1199 C  CG  . ARG   A 1 155 ? -38.18769 -0.44319  -2.37565  1.000 52.74199  ? 155 ARG   A CG  1 
ATOM   1200 C  CD  . ARG   A 1 155 ? -37.79697 0.10640   -3.74964  1.000 60.35682  ? 155 ARG   A CD  1 
ATOM   1201 N  NE  . ARG   A 1 155 ? -37.83196 1.56868   -3.81413  1.000 81.35320  ? 155 ARG   A NE  1 
ATOM   1202 C  CZ  . ARG   A 1 155 ? -37.06414 2.39397   -3.11086  1.000 80.10905  ? 155 ARG   A CZ  1 
ATOM   1203 N  NH1 . ARG   A 1 155 ? -36.13038 1.94548   -2.28691  1.000 78.57690  ? 155 ARG   A NH1 1 
ATOM   1204 N  NH2 . ARG   A 1 155 ? -37.22805 3.70498   -3.25034  1.000 77.84606  ? 155 ARG   A NH2 1 
ATOM   1205 N  N   . MET   A 1 156 ? -37.31373 -4.00799  -1.18608  1.000 47.63805  ? 156 MET   A N   1 
ATOM   1206 C  CA  . MET   A 1 156 ? -36.13081 -4.38640  -0.41968  1.000 53.69815  ? 156 MET   A CA  1 
ATOM   1207 C  C   . MET   A 1 156 ? -35.26994 -5.38863  -1.17341  1.000 56.66679  ? 156 MET   A C   1 
ATOM   1208 O  O   . MET   A 1 156 ? -34.04354 -5.40176  -1.00618  1.000 60.04464  ? 156 MET   A O   1 
ATOM   1209 C  CB  . MET   A 1 156 ? -36.52047 -4.94329  0.95004   1.000 50.39944  ? 156 MET   A CB  1 
ATOM   1210 C  CG  . MET   A 1 156 ? -37.16236 -3.90351  1.87476   1.000 52.11369  ? 156 MET   A CG  1 
ATOM   1211 S  SD  . MET   A 1 156 ? -37.73830 -4.63098  3.42827   1.000 56.08099  ? 156 MET   A SD  1 
ATOM   1212 C  CE  . MET   A 1 156 ? -36.25078 -5.48793  3.96482   1.000 52.15632  ? 156 MET   A CE  1 
ATOM   1213 N  N   . ARG   A 1 157 ? -35.88004 -6.22361  -2.01140  1.000 52.01448  ? 157 ARG   A N   1 
ATOM   1214 C  CA  . ARG   A 1 157 ? -35.08763 -7.16733  -2.79159  1.000 56.24738  ? 157 ARG   A CA  1 
ATOM   1215 C  C   . ARG   A 1 157 ? -34.23752 -6.44152  -3.83085  1.000 54.67173  ? 157 ARG   A C   1 
ATOM   1216 O  O   . ARG   A 1 157 ? -33.05765 -6.76646  -4.01467  1.000 57.66098  ? 157 ARG   A O   1 
ATOM   1217 C  CB  . ARG   A 1 157 ? -36.00687 -8.19435  -3.45125  1.000 49.38959  ? 157 ARG   A CB  1 
ATOM   1218 C  CG  . ARG   A 1 157 ? -36.58580 -9.21811  -2.47161  1.000 54.68860  ? 157 ARG   A CG  1 
ATOM   1219 C  CD  . ARG   A 1 157 ? -37.19677 -10.42407 -3.19494  1.000 46.78419  ? 157 ARG   A CD  1 
ATOM   1220 N  NE  . ARG   A 1 157 ? -38.35829 -10.05730 -3.99444  1.000 62.72694  ? 157 ARG   A NE  1 
ATOM   1221 C  CZ  . ARG   A 1 157 ? -39.61002 -10.06947 -3.55235  1.000 61.34310  ? 157 ARG   A CZ  1 
ATOM   1222 N  NH1 . ARG   A 1 157 ? -39.89850 -10.40400 -2.30461  1.000 53.70853  ? 157 ARG   A NH1 1 
ATOM   1223 N  NH2 . ARG   A 1 157 ? -40.59840 -9.74439  -4.38590  1.000 54.00898  ? 157 ARG   A NH2 1 
ATOM   1224 N  N   . ALA   A 1 158 ? -34.81513 -5.44008  -4.50254  1.000 52.92312  ? 158 ALA   A N   1 
ATOM   1225 C  CA  . ALA   A 1 158 ? -34.06794 -4.64874  -5.47886  1.000 65.57768  ? 158 ALA   A CA  1 
ATOM   1226 C  C   . ALA   A 1 158 ? -32.96361 -3.83360  -4.81477  1.000 59.96018  ? 158 ALA   A C   1 
ATOM   1227 O  O   . ALA   A 1 158 ? -31.88212 -3.65204  -5.38880  1.000 65.98461  ? 158 ALA   A O   1 
ATOM   1228 C  CB  . ALA   A 1 158 ? -35.01989 -3.72406  -6.23852  1.000 50.20901  ? 158 ALA   A CB  1 
ATOM   1229 N  N   . ASP   A 1 159 ? -33.22279 -3.32052  -3.61161  1.000 62.38638  ? 159 ASP   A N   1 
ATOM   1230 C  CA  . ASP   A 1 159 ? -32.20931 -2.54901  -2.90012  1.000 52.58924  ? 159 ASP   A CA  1 
ATOM   1231 C  C   . ASP   A 1 159 ? -31.01944 -3.41580  -2.49753  1.000 63.82122  ? 159 ASP   A C   1 
ATOM   1232 O  O   . ASP   A 1 159 ? -29.89327 -2.91254  -2.39862  1.000 59.60732  ? 159 ASP   A O   1 
ATOM   1233 C  CB  . ASP   A 1 159 ? -32.83287 -1.89350  -1.66920  1.000 52.33499  ? 159 ASP   A CB  1 
ATOM   1234 C  CG  . ASP   A 1 159 ? -33.69416 -0.68686  -2.01850  1.000 74.15064  ? 159 ASP   A CG  1 
ATOM   1235 O  OD1 . ASP   A 1 159 ? -33.65194 -0.23398  -3.18761  1.000 70.10052  ? 159 ASP   A OD1 1 
ATOM   1236 O  OD2 . ASP   A 1 159 ? -34.42988 -0.20550  -1.12485  1.000 55.17479  ? 159 ASP   A OD2 1 
ATOM   1237 N  N   . SER   A 1 160 ? -31.24158 -4.71272  -2.25386  1.000 57.19306  ? 160 SER   A N   1 
ATOM   1238 C  CA  . SER   A 1 160 ? -30.13175 -5.58856  -1.88437  1.000 71.50017  ? 160 SER   A CA  1 
ATOM   1239 C  C   . SER   A 1 160 ? -29.30583 -6.02410  -3.08630  1.000 68.97861  ? 160 SER   A C   1 
ATOM   1240 O  O   . SER   A 1 160 ? -28.08190 -6.14383  -2.96994  1.000 74.55281  ? 160 SER   A O   1 
ATOM   1241 C  CB  . SER   A 1 160 ? -30.64134 -6.81601  -1.12941  1.000 54.42133  ? 160 SER   A CB  1 
ATOM   1242 O  OG  . SER   A 1 160 ? -31.17125 -6.41842  0.11931   1.000 80.37060  ? 160 SER   A OG  1 
ATOM   1243 N  N   . LYS   A 1 161 ? -29.94057 -6.26927  -4.23653  1.000 68.44617  ? 161 LYS   A N   1 
ATOM   1244 C  CA  . LYS   A 1 161 ? -29.17330 -6.60439  -5.43323  1.000 66.26932  ? 161 LYS   A CA  1 
ATOM   1245 C  C   . LYS   A 1 161 ? -28.26695 -5.44985  -5.84160  1.000 79.18786  ? 161 LYS   A C   1 
ATOM   1246 O  O   . LYS   A 1 161 ? -27.12059 -5.66802  -6.25319  1.000 86.10438  ? 161 LYS   A O   1 
ATOM   1247 C  CB  . LYS   A 1 161 ? -30.10769 -6.98667  -6.58267  1.000 59.87165  ? 161 LYS   A CB  1 
ATOM   1248 N  N   . ALA   A 1 162 ? -28.75684 -4.21287  -5.71415  1.000 81.29342  ? 162 ALA   A N   1 
ATOM   1249 C  CA  . ALA   A 1 162 ? -27.94380 -3.04978  -6.05636  1.000 77.92524  ? 162 ALA   A CA  1 
ATOM   1250 C  C   . ALA   A 1 162 ? -26.83451 -2.81518  -5.03826  1.000 80.05146  ? 162 ALA   A C   1 
ATOM   1251 O  O   . ALA   A 1 162 ? -25.74327 -2.36269  -5.40414  1.000 88.90714  ? 162 ALA   A O   1 
ATOM   1252 C  CB  . ALA   A 1 162 ? -28.82857 -1.81037  -6.17602  1.000 69.12283  ? 162 ALA   A CB  1 
ATOM   1253 N  N   . ALA   A 1 163 ? -27.08781 -3.11141  -3.76559  1.000 78.84153  ? 163 ALA   A N   1 
ATOM   1254 C  CA  . ALA   A 1 163 ? -26.06591 -3.01875  -2.73293  1.000 80.79142  ? 163 ALA   A CA  1 
ATOM   1255 C  C   . ALA   A 1 163 ? -25.15536 -4.24360  -2.68246  1.000 74.72145  ? 163 ALA   A C   1 
ATOM   1256 O  O   . ALA   A 1 163 ? -24.59350 -4.52869  -1.61904  1.000 98.28750  ? 163 ALA   A O   1 
ATOM   1257 C  CB  . ALA   A 1 163 ? -26.71743 -2.80079  -1.36480  1.000 68.69328  ? 163 ALA   A CB  1 
ATOM   1258 N  N   . ASN   A 1 164 ? -24.99182 -4.97280  -3.78334  1.000 78.60997  ? 164 ASN   A N   1 
ATOM   1259 C  CA  . ASN   A 1 164 ? -24.10877 -6.13941  -3.78958  1.000 96.20422  ? 164 ASN   A CA  1 
ATOM   1260 C  C   . ASN   A 1 164 ? -22.91736 -5.94401  -4.72971  1.000 94.92589  ? 164 ASN   A C   1 
ATOM   1261 O  O   . ASN   A 1 164 ? -22.33860 -4.85483  -4.80373  1.000 102.21105 ? 164 ASN   A O   1 
ATOM   1262 C  CB  . ASN   A 1 164 ? -24.88686 -7.39666  -4.18106  1.000 86.07999  ? 164 ASN   A CB  1 
ATOM   1263 N  N   . MET   A 1 172 ? -20.89298 -13.78806 1.62460   1.000 80.76472  ? 172 MET   A N   1 
ATOM   1264 C  CA  . MET   A 1 172 ? -19.76963 -13.92276 2.54549   1.000 88.46845  ? 172 MET   A CA  1 
ATOM   1265 C  C   . MET   A 1 172 ? -19.75544 -15.30819 3.17888   1.000 90.05465  ? 172 MET   A C   1 
ATOM   1266 O  O   . MET   A 1 172 ? -20.81039 -15.89365 3.44307   1.000 87.73546  ? 172 MET   A O   1 
ATOM   1267 C  CB  . MET   A 1 172 ? -19.83053 -12.84795 3.63234   1.000 82.71714  ? 172 MET   A CB  1 
ATOM   1268 C  CG  . MET   A 1 172 ? -19.08871 -11.56623 3.29159   1.000 84.64426  ? 172 MET   A CG  1 
ATOM   1269 S  SD  . MET   A 1 172 ? -17.48304 -11.44187 4.10134   1.000 104.98105 ? 172 MET   A SD  1 
ATOM   1270 C  CE  . MET   A 1 172 ? -17.06683 -9.72377  3.78468   1.000 78.24602  ? 172 MET   A CE  1 
ATOM   1271 N  N   . ASP   A 1 173 ? -18.55509 -15.82726 3.41599   1.000 82.16341  ? 173 ASP   A N   1 
ATOM   1272 C  CA  . ASP   A 1 173 ? -18.37515 -17.11942 4.05791   1.000 65.32330  ? 173 ASP   A CA  1 
ATOM   1273 C  C   . ASP   A 1 173 ? -18.38880 -16.94445 5.57541   1.000 56.74193  ? 173 ASP   A C   1 
ATOM   1274 O  O   . ASP   A 1 173 ? -18.38357 -15.82769 6.09955   1.000 66.45293  ? 173 ASP   A O   1 
ATOM   1275 C  CB  . ASP   A 1 173 ? -17.06575 -17.76721 3.60120   1.000 58.33326  ? 173 ASP   A CB  1 
ATOM   1276 C  CG  . ASP   A 1 173 ? -17.05695 -19.28552 3.78490   1.000 72.51574  ? 173 ASP   A CG  1 
ATOM   1277 O  OD1 . ASP   A 1 173 ? -16.09353 -19.93258 3.31696   1.000 84.63267  ? 173 ASP   A OD1 1 
ATOM   1278 O  OD2 . ASP   A 1 173 ? -18.02265 -19.83457 4.36204   1.000 60.50936  ? 173 ASP   A OD2 1 
ATOM   1279 N  N   . VAL   A 1 174 ? -18.38969 -18.07427 6.28426   1.000 57.87730  ? 174 VAL   A N   1 
ATOM   1280 C  CA  . VAL   A 1 174 ? -18.46424 -18.04646 7.74140   1.000 54.32535  ? 174 VAL   A CA  1 
ATOM   1281 C  C   . VAL   A 1 174 ? -17.14196 -17.56626 8.33760   1.000 58.01637  ? 174 VAL   A C   1 
ATOM   1282 O  O   . VAL   A 1 174 ? -16.06718 -17.64262 7.72342   1.000 55.60690  ? 174 VAL   A O   1 
ATOM   1283 C  CB  . VAL   A 1 174 ? -18.84188 -19.43430 8.29115   1.000 56.66600  ? 174 VAL   A CB  1 
ATOM   1284 C  CG1 . VAL   A 1 174 ? -20.11857 -19.94253 7.64012   1.000 46.90990  ? 174 VAL   A CG1 1 
ATOM   1285 C  CG2 . VAL   A 1 174 ? -17.69097 -20.41526 8.08676   1.000 50.49757  ? 174 VAL   A CG2 1 
ATOM   1286 N  N   . ASN   A 1 175 ? -17.22594 -17.08358 9.56352   1.000 59.02677  ? 175 ASN   A N   1 
ATOM   1287 C  CA  . ASN   A 1 175 ? -16.03637 -16.76873 10.34942  1.000 59.13419  ? 175 ASN   A CA  1 
ATOM   1288 C  C   . ASN   A 1 175 ? -15.56252 -18.03172 11.05777  1.000 64.51648  ? 175 ASN   A C   1 
ATOM   1289 O  O   . ASN   A 1 175 ? -16.38205 -18.71997 11.68509  1.000 58.69982  ? 175 ASN   A O   1 
ATOM   1290 C  CB  . ASN   A 1 175 ? -16.33941 -15.68261 11.37982  1.000 50.66870  ? 175 ASN   A CB  1 
ATOM   1291 C  CG  . ASN   A 1 175 ? -15.09681 -15.17864 12.09097  1.000 61.17369  ? 175 ASN   A CG  1 
ATOM   1292 O  OD1 . ASN   A 1 175 ? -14.53616 -15.86214 12.94993  1.000 62.11809  ? 175 ASN   A OD1 1 
ATOM   1293 N  ND2 . ASN   A 1 175 ? -14.68165 -13.95293 11.76371  1.000 72.06991  ? 175 ASN   A ND2 1 
ATOM   1294 N  N   . PRO   A 1 176 ? -14.26694 -18.37199 10.96712  1.000 63.04424  ? 176 PRO   A N   1 
ATOM   1295 C  CA  . PRO   A 1 176 ? -13.77895 -19.60103 11.62246  1.000 52.21567  ? 176 PRO   A CA  1 
ATOM   1296 C  C   . PRO   A 1 176 ? -13.90576 -19.57426 13.13429  1.000 54.89594  ? 176 PRO   A C   1 
ATOM   1297 O  O   . PRO   A 1 176 ? -14.18955 -20.60996 13.74660  1.000 64.03590  ? 176 PRO   A O   1 
ATOM   1298 C  CB  . PRO   A 1 176 ? -12.30475 -19.65821 11.19312  1.000 53.96391  ? 176 PRO   A CB  1 
ATOM   1299 C  CG  . PRO   A 1 176 ? -12.24856 -18.85798 9.92726   1.000 65.26401  ? 176 PRO   A CG  1 
ATOM   1300 C  CD  . PRO   A 1 176 ? -13.21410 -17.72533 10.16734  1.000 55.07792  ? 176 PRO   A CD  1 
ATOM   1301 N  N   . GLN   A 1 177 ? -13.68987 -18.41476 13.75823  1.000 58.39466  ? 177 GLN   A N   1 
ATOM   1302 C  CA  . GLN   A 1 177 ? -13.82277 -18.31702 15.20734  1.000 65.49026  ? 177 GLN   A CA  1 
ATOM   1303 C  C   . GLN   A 1 177 ? -15.27692 -18.43614 15.64373  1.000 56.10475  ? 177 GLN   A C   1 
ATOM   1304 O  O   . GLN   A 1 177 ? -15.55164 -18.90402 16.75573  1.000 56.43841  ? 177 GLN   A O   1 
ATOM   1305 C  CB  . GLN   A 1 177 ? -13.21966 -16.99801 15.70108  1.000 56.37648  ? 177 GLN   A CB  1 
ATOM   1306 N  N   . ALA   A 1 178 ? -16.21509 -18.02088 14.78758  1.000 54.85110  ? 178 ALA   A N   1 
ATOM   1307 C  CA  . ALA   A 1 178 ? -17.63329 -18.19582 15.09065  1.000 62.83537  ? 178 ALA   A CA  1 
ATOM   1308 C  C   . ALA   A 1 178 ? -18.02707 -19.66839 15.05490  1.000 55.43634  ? 178 ALA   A C   1 
ATOM   1309 O  O   . ALA   A 1 178 ? -18.86005 -20.11514 15.85388  1.000 56.76683  ? 178 ALA   A O   1 
ATOM   1310 C  CB  . ALA   A 1 178 ? -18.48448 -17.38831 14.10931  1.000 45.96192  ? 178 ALA   A CB  1 
ATOM   1311 N  N   . VAL   A 1 179 ? -17.44255 -20.43560 14.13212  1.000 52.02661  ? 179 VAL   A N   1 
ATOM   1312 C  CA  . VAL   A 1 179 ? -17.68136 -21.87764 14.10043  1.000 49.94001  ? 179 VAL   A CA  1 
ATOM   1313 C  C   . VAL   A 1 179 ? -17.22990 -22.51567 15.40939  1.000 53.90124  ? 179 VAL   A C   1 
ATOM   1314 O  O   . VAL   A 1 179 ? -18.00044 -23.21655 16.07459  1.000 51.87903  ? 179 VAL   A O   1 
ATOM   1315 C  CB  . VAL   A 1 179 ? -16.97817 -22.51178 12.88517  1.000 52.32918  ? 179 VAL   A CB  1 
ATOM   1316 C  CG1 . VAL   A 1 179 ? -17.06402 -24.04020 12.93980  1.000 40.62056  ? 179 VAL   A CG1 1 
ATOM   1317 C  CG2 . VAL   A 1 179 ? -17.58863 -21.98696 11.58624  1.000 47.35556  ? 179 VAL   A CG2 1 
ATOM   1318 N  N   . VAL   A 1 180 ? -15.97977 -22.26106 15.81028  1.000 49.21395  ? 180 VAL   A N   1 
ATOM   1319 C  CA  . VAL   A 1 180 ? -15.45154 -22.86437 17.03251  1.000 53.78915  ? 180 VAL   A CA  1 
ATOM   1320 C  C   . VAL   A 1 180 ? -16.28406 -22.45062 18.24202  1.000 50.00250  ? 180 VAL   A C   1 
ATOM   1321 O  O   . VAL   A 1 180 ? -16.53537 -23.25782 19.14636  1.000 60.60927  ? 180 VAL   A O   1 
ATOM   1322 C  CB  . VAL   A 1 180 ? -13.96244 -22.49963 17.21001  1.000 64.41821  ? 180 VAL   A CB  1 
ATOM   1323 C  CG1 . VAL   A 1 180 ? -13.42905 -23.01328 18.54242  1.000 54.68466  ? 180 VAL   A CG1 1 
ATOM   1324 C  CG2 . VAL   A 1 180 ? -13.13649 -23.06399 16.06345  1.000 66.11516  ? 180 VAL   A CG2 1 
ATOM   1325 N  N   . ASP   A 1 181 ? -16.73119 -21.19366 18.27482  1.000 54.55194  ? 181 ASP   A N   1 
ATOM   1326 C  CA  . ASP   A 1 181 ? -17.50289 -20.70476 19.41675  1.000 65.28719  ? 181 ASP   A CA  1 
ATOM   1327 C  C   . ASP   A 1 181 ? -18.79799 -21.49205 19.59413  1.000 55.59790  ? 181 ASP   A C   1 
ATOM   1328 O  O   . ASP   A 1 181 ? -19.12812 -21.92995 20.70273  1.000 60.48929  ? 181 ASP   A O   1 
ATOM   1329 C  CB  . ASP   A 1 181 ? -17.79869 -19.21502 19.24787  1.000 65.46138  ? 181 ASP   A CB  1 
ATOM   1330 C  CG  . ASP   A 1 181 ? -18.62171 -18.65523 20.38960  1.000 82.56162  ? 181 ASP   A CG  1 
ATOM   1331 O  OD1 . ASP   A 1 181 ? -18.01771 -18.28400 21.41853  1.000 92.17043  ? 181 ASP   A OD1 1 
ATOM   1332 O  OD2 . ASP   A 1 181 ? -19.86944 -18.58610 20.25532  1.000 79.83229  ? 181 ASP   A OD2 1 
ATOM   1333 N  N   . ALA   A 1 182 ? -19.54199 -21.69179 18.50808  1.000 54.85194  ? 182 ALA   A N   1 
ATOM   1334 C  CA  . ALA   A 1 182 ? -20.80653 -22.41589 18.60612  1.000 56.70918  ? 182 ALA   A CA  1 
ATOM   1335 C  C   . ALA   A 1 182 ? -20.57995 -23.88884 18.94112  1.000 57.13318  ? 182 ALA   A C   1 
ATOM   1336 O  O   . ALA   A 1 182 ? -21.27338 -24.45854 19.79242  1.000 58.34580  ? 182 ALA   A O   1 
ATOM   1337 C  CB  . ALA   A 1 182 ? -21.58724 -22.26702 17.30271  1.000 49.97351  ? 182 ALA   A CB  1 
ATOM   1338 N  N   . MET   A 1 183 ? -19.60207 -24.51997 18.28773  1.000 55.62103  ? 183 MET   A N   1 
ATOM   1339 C  CA  . MET   A 1 183 ? -19.32345 -25.92947 18.53963  1.000 52.62504  ? 183 MET   A CA  1 
ATOM   1340 C  C   . MET   A 1 183 ? -18.78670 -26.17041 19.94821  1.000 56.56849  ? 183 MET   A C   1 
ATOM   1341 O  O   . MET   A 1 183 ? -18.91572 -27.28537 20.46833  1.000 64.66799  ? 183 MET   A O   1 
ATOM   1342 C  CB  . MET   A 1 183 ? -18.32871 -26.45818 17.50351  1.000 50.29652  ? 183 MET   A CB  1 
ATOM   1343 C  CG  . MET   A 1 183 ? -18.85211 -26.41773 16.07776  1.000 41.94915  ? 183 MET   A CG  1 
ATOM   1344 S  SD  . MET   A 1 183 ? -17.79663 -27.33822 14.93484  1.000 52.49946  ? 183 MET   A SD  1 
ATOM   1345 C  CE  . MET   A 1 183 ? -18.53580 -28.97685 15.05865  1.000 51.73470  ? 183 MET   A CE  1 
ATOM   1346 N  N   . GLU   A 1 184 ? -18.18603 -25.15867 20.57536  1.000 51.30313  ? 184 GLU   A N   1 
ATOM   1347 C  CA  . GLU   A 1 184 ? -17.75685 -25.27339 21.96457  1.000 62.63229  ? 184 GLU   A CA  1 
ATOM   1348 C  C   . GLU   A 1 184 ? -18.86388 -24.92415 22.96186  1.000 61.78095  ? 184 GLU   A C   1 
ATOM   1349 O  O   . GLU   A 1 184 ? -18.91140 -25.51432 24.04990  1.000 63.88488  ? 184 GLU   A O   1 
ATOM   1350 C  CB  . GLU   A 1 184 ? -16.53017 -24.38579 22.20775  1.000 54.27527  ? 184 GLU   A CB  1 
ATOM   1351 N  N   . ARG   A 1 185 ? -19.74746 -23.97338 22.62718  1.000 55.61058  ? 185 ARG   A N   1 
ATOM   1352 C  CA  . ARG   A 1 185 ? -20.90582 -23.70262 23.47920  1.000 66.07497  ? 185 ARG   A CA  1 
ATOM   1353 C  C   . ARG   A 1 185 ? -21.78278 -24.93929 23.63712  1.000 62.45985  ? 185 ARG   A C   1 
ATOM   1354 O  O   . ARG   A 1 185 ? -22.26276 -25.22846 24.73925  1.000 68.47242  ? 185 ARG   A O   1 
ATOM   1355 C  CB  . ARG   A 1 185 ? -21.74223 -22.54983 22.91415  1.000 63.89218  ? 185 ARG   A CB  1 
ATOM   1356 C  CG  . ARG   A 1 185 ? -21.17849 -21.15407 23.14399  1.000 76.46198  ? 185 ARG   A CG  1 
ATOM   1357 C  CD  . ARG   A 1 185 ? -22.23087 -20.07477 22.82387  1.000 62.93187  ? 185 ARG   A CD  1 
ATOM   1358 N  NE  . ARG   A 1 185 ? -22.19500 -19.72696 21.40619  1.000 69.36392  ? 185 ARG   A NE  1 
ATOM   1359 C  CZ  . ARG   A 1 185 ? -23.14324 -20.03815 20.52963  1.000 67.00642  ? 185 ARG   A CZ  1 
ATOM   1360 N  NH1 . ARG   A 1 185 ? -24.25479 -20.65408 20.89919  1.000 55.87534  ? 185 ARG   A NH1 1 
ATOM   1361 N  NH2 . ARG   A 1 185 ? -22.96882 -19.73178 19.24706  1.000 62.67360  ? 185 ARG   A NH2 1 
ATOM   1362 N  N   . HIS   A 1 186 ? -22.00967 -25.67522 22.54587  1.000 54.83790  ? 186 HIS   A N   1 
ATOM   1363 C  CA  . HIS   A 1 186 ? -22.83676 -26.87796 22.55804  1.000 64.86999  ? 186 HIS   A CA  1 
ATOM   1364 C  C   . HIS   A 1 186 ? -22.05343 -28.16103 22.83282  1.000 66.91391  ? 186 HIS   A C   1 
ATOM   1365 O  O   . HIS   A 1 186 ? -22.67250 -29.22426 22.96267  1.000 56.70160  ? 186 HIS   A O   1 
ATOM   1366 C  CB  . HIS   A 1 186 ? -23.57153 -27.02332 21.22000  1.000 56.39674  ? 186 HIS   A CB  1 
ATOM   1367 C  CG  . HIS   A 1 186 ? -24.52916 -25.90980 20.92288  1.000 61.58092  ? 186 HIS   A CG  1 
ATOM   1368 N  ND1 . HIS   A 1 186 ? -25.85145 -25.94123 21.31280  1.000 65.90613  ? 186 HIS   A ND1 1 
ATOM   1369 C  CD2 . HIS   A 1 186 ? -24.35910 -24.73660 20.26593  1.000 62.25998  ? 186 HIS   A CD2 1 
ATOM   1370 C  CE1 . HIS   A 1 186 ? -26.45498 -24.83717 20.90707  1.000 62.73488  ? 186 HIS   A CE1 1 
ATOM   1371 N  NE2 . HIS   A 1 186 ? -25.57126 -24.08804 20.27169  1.000 61.85601  ? 186 HIS   A NE2 1 
ATOM   1372 N  N   A HIS   A 1 187 ? -20.72232 -28.08319 22.90412  0.406 63.67478  ? 187 HIS   A N   1 
ATOM   1373 N  N   B HIS   A 1 187 ? -20.72370 -28.08880 22.92649  0.594 63.71469  ? 187 HIS   A N   1 
ATOM   1374 C  CA  A HIS   A 1 187 ? -19.86252 -29.23804 23.17067  0.406 60.28326  ? 187 HIS   A CA  1 
ATOM   1375 C  CA  B HIS   A 1 187 ? -19.86545 -29.25364 23.17116  0.594 60.29640  ? 187 HIS   A CA  1 
ATOM   1376 C  C   A HIS   A 1 187 ? -20.10543 -30.36170 22.16114  0.406 56.52885  ? 187 HIS   A C   1 
ATOM   1377 C  C   B HIS   A 1 187 ? -20.12773 -30.36600 22.15761  0.594 56.49763  ? 187 HIS   A C   1 
ATOM   1378 O  O   A HIS   A 1 187 ? -20.28349 -31.52587 22.52472  0.406 60.54674  ? 187 HIS   A O   1 
ATOM   1379 O  O   B HIS   A 1 187 ? -20.34377 -31.52618 22.51311  0.594 60.59360  ? 187 HIS   A O   1 
ATOM   1380 C  CB  A HIS   A 1 187 ? -20.04716 -29.73846 24.60787  0.406 65.62430  ? 187 HIS   A CB  1 
ATOM   1381 C  CB  B HIS   A 1 187 ? -20.03218 -29.77492 24.60133  0.594 65.67891  ? 187 HIS   A CB  1 
ATOM   1382 C  CG  A HIS   A 1 187 ? -19.63429 -28.74850 25.65622  0.406 67.41760  ? 187 HIS   A CG  1 
ATOM   1383 C  CG  B HIS   A 1 187 ? -18.87030 -30.58527 25.09250  0.594 66.32240  ? 187 HIS   A CG  1 
ATOM   1384 N  ND1 A HIS   A 1 187 ? -20.52268 -28.21069 26.56398  0.406 67.64254  ? 187 HIS   A ND1 1 
ATOM   1385 N  ND1 B HIS   A 1 187 ? -17.60780 -30.05524 25.26193  0.594 68.17109  ? 187 HIS   A ND1 1 
ATOM   1386 C  CD2 A HIS   A 1 187 ? -18.42588 -28.21028 25.95008  0.406 69.05931  ? 187 HIS   A CD2 1 
ATOM   1387 C  CD2 B HIS   A 1 187 ? -18.77874 -31.89218 25.43744  0.594 62.09207  ? 187 HIS   A CD2 1 
ATOM   1388 C  CE1 A HIS   A 1 187 ? -19.88189 -27.37659 27.36434  0.406 66.16746  ? 187 HIS   A CE1 1 
ATOM   1389 C  CE1 B HIS   A 1 187 ? -16.79181 -30.99795 25.69995  0.594 64.76665  ? 187 HIS   A CE1 1 
ATOM   1390 N  NE2 A HIS   A 1 187 ? -18.60846 -27.35834 27.01329  0.406 64.72919  ? 187 HIS   A NE2 1 
ATOM   1391 N  NE2 B HIS   A 1 187 ? -17.47743 -32.12192 25.81397  0.594 66.26781  ? 187 HIS   A NE2 1 
ATOM   1392 N  N   . VAL   A 1 188 ? -20.10169 -30.00534 20.87558  1.000 47.42098  ? 188 VAL   A N   1 
ATOM   1393 C  CA  . VAL   A 1 188 ? -20.28982 -30.97317 19.79990  1.000 50.02817  ? 188 VAL   A CA  1 
ATOM   1394 C  C   . VAL   A 1 188 ? -19.03386 -31.04003 18.93667  1.000 60.03636  ? 188 VAL   A C   1 
ATOM   1395 O  O   . VAL   A 1 188 ? -18.20482 -30.12531 18.91378  1.000 48.34433  ? 188 VAL   A O   1 
ATOM   1396 C  CB  . VAL   A 1 188 ? -21.51362 -30.64960 18.91681  1.000 58.23853  ? 188 VAL   A CB  1 
ATOM   1397 C  CG1 . VAL   A 1 188 ? -22.80937 -30.92304 19.66829  1.000 47.71736  ? 188 VAL   A CG1 1 
ATOM   1398 C  CG2 . VAL   A 1 188 ? -21.44272 -29.20471 18.43896  1.000 45.64074  ? 188 VAL   A CG2 1 
ATOM   1399 N  N   . GLN   A 1 189 ? -18.91669 -32.14536 18.20058  1.000 53.19870  ? 189 GLN   A N   1 
ATOM   1400 C  CA  . GLN   A 1 189 ? -17.83606 -32.35943 17.24951  1.000 50.68618  ? 189 GLN   A CA  1 
ATOM   1401 C  C   . GLN   A 1 189 ? -18.32837 -32.40340 15.81159  1.000 45.69288  ? 189 GLN   A C   1 
ATOM   1402 O  O   . GLN   A 1 189 ? -17.52556 -32.64266 14.90192  1.000 51.23244  ? 189 GLN   A O   1 
ATOM   1403 C  CB  . GLN   A 1 189 ? -17.08390 -33.66091 17.56984  1.000 48.10088  ? 189 GLN   A CB  1 
ATOM   1404 C  CG  . GLN   A 1 189 ? -16.52632 -33.76477 18.99212  1.000 47.29163  ? 189 GLN   A CG  1 
ATOM   1405 C  CD  . GLN   A 1 189 ? -15.64165 -32.58787 19.36679  1.000 53.10905  ? 189 GLN   A CD  1 
ATOM   1406 O  OE1 . GLN   A 1 189 ? -15.82030 -31.96139 20.41525  1.000 63.13893  ? 189 GLN   A OE1 1 
ATOM   1407 N  NE2 . GLN   A 1 189 ? -14.69174 -32.26617 18.49518  1.000 57.96521  ? 189 GLN   A NE2 1 
ATOM   1408 N  N   . TRP   A 1 190 ? -19.62447 -32.19283 15.58596  1.000 44.24755  ? 190 TRP   A N   1 
ATOM   1409 C  CA  . TRP   A 1 190 ? -20.23058 -32.21102 14.26055  1.000 48.22229  ? 190 TRP   A CA  1 
ATOM   1410 C  C   . TRP   A 1 190 ? -21.19346 -31.03878 14.14220  1.000 55.57805  ? 190 TRP   A C   1 
ATOM   1411 O  O   . TRP   A 1 190 ? -21.97741 -30.78164 15.06204  1.000 55.70154  ? 190 TRP   A O   1 
ATOM   1412 C  CB  . TRP   A 1 190 ? -20.98501 -33.53043 14.00721  1.000 57.07806  ? 190 TRP   A CB  1 
ATOM   1413 C  CG  . TRP   A 1 190 ? -20.08198 -34.70883 13.75542  1.000 60.96823  ? 190 TRP   A CG  1 
ATOM   1414 C  CD1 . TRP   A 1 190 ? -19.59746 -35.58754 14.68887  1.000 57.10496  ? 190 TRP   A CD1 1 
ATOM   1415 C  CD2 . TRP   A 1 190 ? -19.55828 -35.13938 12.48996  1.000 58.57413  ? 190 TRP   A CD2 1 
ATOM   1416 N  NE1 . TRP   A 1 190 ? -18.80646 -36.53202 14.08244  1.000 55.76698  ? 190 TRP   A NE1 1 
ATOM   1417 C  CE2 . TRP   A 1 190 ? -18.76222 -36.28241 12.73463  1.000 67.03199  ? 190 TRP   A CE2 1 
ATOM   1418 C  CE3 . TRP   A 1 190 ? -19.68444 -34.67049 11.17629  1.000 49.52806  ? 190 TRP   A CE3 1 
ATOM   1419 C  CZ2 . TRP   A 1 190 ? -18.08845 -36.96539 11.70997  1.000 61.36139  ? 190 TRP   A CZ2 1 
ATOM   1420 C  CZ3 . TRP   A 1 190 ? -19.02129 -35.34802 10.16050  1.000 67.84673  ? 190 TRP   A CZ3 1 
ATOM   1421 C  CH2 . TRP   A 1 190 ? -18.23094 -36.48762 10.43411  1.000 62.77298  ? 190 TRP   A CH2 1 
ATOM   1422 N  N   . LEU   A 1 191 ? -21.12982 -30.32872 13.01426  1.000 44.14039  ? 191 LEU   A N   1 
ATOM   1423 C  CA  . LEU   A 1 191 ? -22.02697 -29.20850 12.74393  1.000 48.99124  ? 191 LEU   A CA  1 
ATOM   1424 C  C   . LEU   A 1 191 ? -22.50061 -29.30519 11.30311  1.000 44.10276  ? 191 LEU   A C   1 
ATOM   1425 O  O   . LEU   A 1 191 ? -21.70182 -29.57868 10.40065  1.000 43.74110  ? 191 LEU   A O   1 
ATOM   1426 C  CB  . LEU   A 1 191 ? -21.33485 -27.85568 12.99720  1.000 43.28423  ? 191 LEU   A CB  1 
ATOM   1427 C  CG  . LEU   A 1 191 ? -21.85640 -26.59125 12.29796  1.000 54.05770  ? 191 LEU   A CG  1 
ATOM   1428 C  CD1 . LEU   A 1 191 ? -23.23287 -26.11401 12.80426  1.000 36.39369  ? 191 LEU   A CD1 1 
ATOM   1429 C  CD2 . LEU   A 1 191 ? -20.82274 -25.48091 12.41171  1.000 43.51176  ? 191 LEU   A CD2 1 
ATOM   1430 N  N   . ILE   A 1 192 ? -23.79905 -29.11035 11.09623  1.000 45.77558  ? 192 ILE   A N   1 
ATOM   1431 C  CA  . ILE   A 1 192 ? -24.41142 -29.12134 9.77085   1.000 45.87268  ? 192 ILE   A CA  1 
ATOM   1432 C  C   . ILE   A 1 192 ? -25.12230 -27.79028 9.57737   1.000 49.81539  ? 192 ILE   A C   1 
ATOM   1433 O  O   . ILE   A 1 192 ? -25.86786 -27.35174 10.46266  1.000 40.06075  ? 192 ILE   A O   1 
ATOM   1434 C  CB  . ILE   A 1 192 ? -25.40463 -30.28797 9.61030   1.000 36.31127  ? 192 ILE   A CB  1 
ATOM   1435 C  CG1 . ILE   A 1 192 ? -24.76795 -31.62334 9.99451   1.000 34.42140  ? 192 ILE   A CG1 1 
ATOM   1436 C  CG2 . ILE   A 1 192 ? -25.94821 -30.36237 8.18517   1.000 40.57443  ? 192 ILE   A CG2 1 
ATOM   1437 C  CD1 . ILE   A 1 192 ? -25.79441 -32.78996 10.02820  1.000 31.97569  ? 192 ILE   A CD1 1 
ATOM   1438 N  N   . HIS   A 1 193 ? -24.89756 -27.14937 8.43018   1.000 38.70633  ? 193 HIS   A N   1 
ATOM   1439 C  CA  . HIS   A 1 193 ? -25.57723 -25.89465 8.12829   1.000 33.48265  ? 193 HIS   A CA  1 
ATOM   1440 C  C   . HIS   A 1 193 ? -25.63161 -25.70196 6.61810   1.000 42.03571  ? 193 HIS   A C   1 
ATOM   1441 O  O   . HIS   A 1 193 ? -25.09017 -26.49798 5.84383   1.000 37.89267  ? 193 HIS   A O   1 
ATOM   1442 C  CB  . HIS   A 1 193 ? -24.89500 -24.71805 8.82413   1.000 39.10599  ? 193 HIS   A CB  1 
ATOM   1443 C  CG  . HIS   A 1 193 ? -23.58379 -24.32259 8.21273   1.000 47.65470  ? 193 HIS   A CG  1 
ATOM   1444 N  ND1 . HIS   A 1 193 ? -23.48863 -23.53726 7.08232   1.000 51.04585  ? 193 HIS   A ND1 1 
ATOM   1445 C  CD2 . HIS   A 1 193 ? -22.31087 -24.58980 8.59283   1.000 45.15835  ? 193 HIS   A CD2 1 
ATOM   1446 C  CE1 . HIS   A 1 193 ? -22.21260 -23.34008 6.79226   1.000 50.49077  ? 193 HIS   A CE1 1 
ATOM   1447 N  NE2 . HIS   A 1 193 ? -21.47826 -23.96871 7.69196   1.000 43.86074  ? 193 HIS   A NE2 1 
ATOM   1448 N  N   . GLY   A 1 194 ? -26.30109 -24.62985 6.20562   1.000 39.39287  ? 194 GLY   A N   1 
ATOM   1449 C  CA  . GLY   A 1 194 ? -26.33081 -24.24201 4.81055   1.000 43.90603  ? 194 GLY   A CA  1 
ATOM   1450 C  C   . GLY   A 1 194 ? -25.93067 -22.79162 4.62696   1.000 46.11406  ? 194 GLY   A C   1 
ATOM   1451 O  O   . GLY   A 1 194 ? -24.84082 -22.37677 5.04840   1.000 48.03844  ? 194 GLY   A O   1 
ATOM   1452 N  N   . HIS   A 1 195 ? -26.81495 -22.02270 3.98365   1.000 48.17726  ? 195 HIS   A N   1 
ATOM   1453 C  CA  . HIS   A 1 195 ? -26.69213 -20.57922 3.78286   1.000 41.41972  ? 195 HIS   A CA  1 
ATOM   1454 C  C   . HIS   A 1 195 ? -25.55735 -20.13960 2.86225   1.000 44.76155  ? 195 HIS   A C   1 
ATOM   1455 O  O   . HIS   A 1 195 ? -25.77665 -19.28590 1.99788   1.000 42.49742  ? 195 HIS   A O   1 
ATOM   1456 C  CB  . HIS   A 1 195 ? -26.52397 -19.83592 5.10352   1.000 31.08670  ? 195 HIS   A CB  1 
ATOM   1457 C  CG  . HIS   A 1 195 ? -26.29840 -18.37446 4.90932   1.000 44.14328  ? 195 HIS   A CG  1 
ATOM   1458 N  ND1 . HIS   A 1 195 ? -27.26968 -17.53922 4.39376   1.000 43.27176  ? 195 HIS   A ND1 1 
ATOM   1459 C  CD2 . HIS   A 1 195 ? -25.21034 -17.59939 5.13019   1.000 42.41124  ? 195 HIS   A CD2 1 
ATOM   1460 C  CE1 . HIS   A 1 195 ? -26.79223 -16.31152 4.31962   1.000 41.13387  ? 195 HIS   A CE1 1 
ATOM   1461 N  NE2 . HIS   A 1 195 ? -25.54542 -16.32156 4.76180   1.000 45.53552  ? 195 HIS   A NE2 1 
ATOM   1462 N  N   . THR   A 1 196 ? -24.33899 -20.66636 3.04736   1.000 43.92075  ? 196 THR   A N   1 
ATOM   1463 C  CA  . THR   A 1 196 ? -23.22320 -20.20557 2.22433   1.000 43.42986  ? 196 THR   A CA  1 
ATOM   1464 C  C   . THR   A 1 196 ? -23.22769 -20.76991 0.80928   1.000 55.67288  ? 196 THR   A C   1 
ATOM   1465 O  O   . THR   A 1 196 ? -22.51006 -20.23345 -0.04178  1.000 42.94536  ? 196 THR   A O   1 
ATOM   1466 C  CB  . THR   A 1 196 ? -21.88464 -20.53906 2.87408   1.000 52.76141  ? 196 THR   A CB  1 
ATOM   1467 O  OG1 . THR   A 1 196 ? -21.74370 -21.96581 2.98057   1.000 46.28431  ? 196 THR   A OG1 1 
ATOM   1468 C  CG2 . THR   A 1 196 ? -21.75759 -19.85759 4.23556   1.000 42.23302  ? 196 THR   A CG2 1 
ATOM   1469 N  N   . HIS   A 1 197 ? -24.00052 -21.82759 0.53623   1.000 47.55959  ? 197 HIS   A N   1 
ATOM   1470 C  CA  . HIS   A 1 197 ? -24.08422 -22.41320 -0.80481  1.000 49.75113  ? 197 HIS   A CA  1 
ATOM   1471 C  C   . HIS   A 1 197 ? -22.74462 -23.00235 -1.25624  1.000 49.70909  ? 197 HIS   A C   1 
ATOM   1472 O  O   . HIS   A 1 197 ? -22.47152 -23.09818 -2.45928  1.000 45.22029  ? 197 HIS   A O   1 
ATOM   1473 C  CB  . HIS   A 1 197 ? -24.57078 -21.38973 -1.84758  1.000 49.55191  ? 197 HIS   A CB  1 
ATOM   1474 C  CG  . HIS   A 1 197 ? -25.92724 -20.81176 -1.57370  1.000 47.30327  ? 197 HIS   A CG  1 
ATOM   1475 N  ND1 . HIS   A 1 197 ? -26.53593 -19.92549 -2.43621  1.000 58.19534  ? 197 HIS   A ND1 1 
ATOM   1476 C  CD2 . HIS   A 1 197 ? -26.79744 -20.99704 -0.55051  1.000 40.61192  ? 197 HIS   A CD2 1 
ATOM   1477 C  CE1 . HIS   A 1 197 ? -27.71719 -19.58148 -1.95287  1.000 43.96183  ? 197 HIS   A CE1 1 
ATOM   1478 N  NE2 . HIS   A 1 197 ? -27.90269 -20.22148 -0.81149  1.000 51.17722  ? 197 HIS   A NE2 1 
ATOM   1479 N  N   . ARG   A 1 198 ? -21.88613 -23.39168 -0.30769  1.000 41.65044  ? 198 ARG   A N   1 
ATOM   1480 C  CA  . ARG   A 1 198 ? -20.55516 -23.92881 -0.60076  1.000 41.66919  ? 198 ARG   A CA  1 
ATOM   1481 C  C   . ARG   A 1 198 ? -20.47677 -25.33944 -0.02800  1.000 43.81769  ? 198 ARG   A C   1 
ATOM   1482 O  O   . ARG   A 1 198 ? -19.85206 -25.55390 1.02193   1.000 46.59081  ? 198 ARG   A O   1 
ATOM   1483 C  CB  . ARG   A 1 198 ? -19.45775 -23.03505 -0.01340  1.000 45.71136  ? 198 ARG   A CB  1 
ATOM   1484 C  CG  . ARG   A 1 198 ? -19.18815 -21.73644 -0.78713  1.000 41.83178  ? 198 ARG   A CG  1 
ATOM   1485 C  CD  . ARG   A 1 198 ? -18.29918 -20.79805 0.02446   1.000 54.45652  ? 198 ARG   A CD  1 
ATOM   1486 N  NE  . ARG   A 1 198 ? -18.17613 -19.46903 -0.57170  1.000 72.95352  ? 198 ARG   A NE  1 
ATOM   1487 C  CZ  . ARG   A 1 198 ? -18.70473 -18.35437 -0.07973  1.000 86.31124  ? 198 ARG   A CZ  1 
ATOM   1488 N  NH1 . ARG   A 1 198 ? -19.45867 -18.36251 1.00833   1.000 85.31824  ? 198 ARG   A NH1 1 
ATOM   1489 N  NH2 . ARG   A 1 198 ? -18.48612 -17.20326 -0.70711  1.000 82.92992  ? 198 ARG   A NH2 1 
ATOM   1490 N  N   . PRO   A 1 199 ? -21.08833 -26.32485 -0.69010  1.000 50.48276  ? 199 PRO   A N   1 
ATOM   1491 C  CA  . PRO   A 1 199 ? -21.11751 -27.68588 -0.12847  1.000 51.03352  ? 199 PRO   A CA  1 
ATOM   1492 C  C   . PRO   A 1 199 ? -19.71007 -28.24787 0.00675   1.000 50.64974  ? 199 PRO   A C   1 
ATOM   1493 O  O   . PRO   A 1 199 ? -18.93203 -28.27511 -0.95178  1.000 51.20064  ? 199 PRO   A O   1 
ATOM   1494 C  CB  . PRO   A 1 199 ? -21.96516 -28.47208 -1.14225  1.000 51.19410  ? 199 PRO   A CB  1 
ATOM   1495 C  CG  . PRO   A 1 199 ? -21.85589 -27.69344 -2.41096  1.000 42.29863  ? 199 PRO   A CG  1 
ATOM   1496 C  CD  . PRO   A 1 199 ? -21.74536 -26.25501 -2.00655  1.000 45.77806  ? 199 PRO   A CD  1 
ATOM   1497 N  N   . ALA   A 1 200 ? -19.38413 -28.68956 1.21825   1.000 43.04599  ? 200 ALA   A N   1 
ATOM   1498 C  CA  . ALA   A 1 200 ? -18.02509 -29.06732 1.57527   1.000 54.46664  ? 200 ALA   A CA  1 
ATOM   1499 C  C   . ALA   A 1 200 ? -18.08427 -29.80233 2.90440   1.000 52.83228  ? 200 ALA   A C   1 
ATOM   1500 O  O   . ALA   A 1 200 ? -19.08797 -29.74373 3.61863   1.000 48.27846  ? 200 ALA   A O   1 
ATOM   1501 C  CB  . ALA   A 1 200 ? -17.10811 -27.83899 1.66262   1.000 34.25047  ? 200 ALA   A CB  1 
ATOM   1502 N  N   . VAL   A 1 201 ? -17.00132 -30.51339 3.21721   1.000 44.27499  ? 201 VAL   A N   1 
ATOM   1503 C  CA  . VAL   A 1 201 ? -16.76834 -31.04981 4.55362   1.000 44.57928  ? 201 VAL   A CA  1 
ATOM   1504 C  C   . VAL   A 1 201 ? -15.46061 -30.43854 5.04861   1.000 55.94322  ? 201 VAL   A C   1 
ATOM   1505 O  O   . VAL   A 1 201 ? -14.42109 -30.56081 4.38488   1.000 47.56222  ? 201 VAL   A O   1 
ATOM   1506 C  CB  . VAL   A 1 201 ? -16.69836 -32.58761 4.56573   1.000 41.44327  ? 201 VAL   A CB  1 
ATOM   1507 C  CG1 . VAL   A 1 201 ? -16.00523 -33.07016 5.82472   1.000 49.38866  ? 201 VAL   A CG1 1 
ATOM   1508 C  CG2 . VAL   A 1 201 ? -18.07738 -33.20455 4.43528   1.000 46.22335  ? 201 VAL   A CG2 1 
ATOM   1509 N  N   . HIS   A 1 202 ? -15.51626 -29.75602 6.18971   1.000 49.13116  ? 202 HIS   A N   1 
ATOM   1510 C  CA  . HIS   A 1 202 ? -14.36133 -29.06951 6.75937   1.000 53.12942  ? 202 HIS   A CA  1 
ATOM   1511 C  C   . HIS   A 1 202 ? -13.98896 -29.73988 8.06895   1.000 46.64392  ? 202 HIS   A C   1 
ATOM   1512 O  O   . HIS   A 1 202 ? -14.86059 -29.99878 8.90414   1.000 60.83237  ? 202 HIS   A O   1 
ATOM   1513 C  CB  . HIS   A 1 202 ? -14.65269 -27.58638 7.02200   1.000 48.46850  ? 202 HIS   A CB  1 
ATOM   1514 C  CG  . HIS   A 1 202 ? -15.11259 -26.82784 5.81674   1.000 51.66028  ? 202 HIS   A CG  1 
ATOM   1515 N  ND1 . HIS   A 1 202 ? -14.24125 -26.18229 4.96180   1.000 45.85051  ? 202 HIS   A ND1 1 
ATOM   1516 C  CD2 . HIS   A 1 202 ? -16.35399 -26.61700 5.31902   1.000 48.46576  ? 202 HIS   A CD2 1 
ATOM   1517 C  CE1 . HIS   A 1 202 ? -14.92743 -25.59937 3.99580   1.000 48.90497  ? 202 HIS   A CE1 1 
ATOM   1518 N  NE2 . HIS   A 1 202 ? -16.21203 -25.84378 4.19151   1.000 52.37217  ? 202 HIS   A NE2 1 
ATOM   1519 N  N   . GLU   A 1 203 ? -12.70440 -30.00748 8.24836   1.000 55.26186  ? 203 GLU   A N   1 
ATOM   1520 C  CA  . GLU   A 1 203 ? -12.17901 -30.53411 9.49587   1.000 57.34295  ? 203 GLU   A CA  1 
ATOM   1521 C  C   . GLU   A 1 203 ? -11.57114 -29.39753 10.30335  1.000 51.41565  ? 203 GLU   A C   1 
ATOM   1522 O  O   . GLU   A 1 203 ? -10.94762 -28.48980 9.74624   1.000 58.76559  ? 203 GLU   A O   1 
ATOM   1523 C  CB  . GLU   A 1 203 ? -11.13076 -31.61227 9.22709   1.000 54.74563  ? 203 GLU   A CB  1 
ATOM   1524 C  CG  . GLU   A 1 203 ? -10.75130 -32.43617 10.43460  1.000 60.39951  ? 203 GLU   A CG  1 
ATOM   1525 C  CD  . GLU   A 1 203 ? -9.83610  -33.59795 10.06905  1.000 85.65531  ? 203 GLU   A CD  1 
ATOM   1526 O  OE1 . GLU   A 1 203 ? -9.15295  -34.13150 10.97106  1.000 80.39059  ? 203 GLU   A OE1 1 
ATOM   1527 O  OE2 . GLU   A 1 203 ? -9.80253  -33.97928 8.87575   1.000 85.91286  ? 203 GLU   A OE2 1 
ATOM   1528 N  N   . LEU   A 1 204 ? -11.76922 -29.44393 11.61550  1.000 54.14444  ? 204 LEU   A N   1 
ATOM   1529 C  CA  . LEU   A 1 204 ? -11.24262 -28.42927 12.51726  1.000 44.83157  ? 204 LEU   A CA  1 
ATOM   1530 C  C   . LEU   A 1 204 ? -11.02173 -29.09035 13.87416  1.000 49.81087  ? 204 LEU   A C   1 
ATOM   1531 O  O   . LEU   A 1 204 ? -11.06794 -30.31729 13.99889  1.000 58.42713  ? 204 LEU   A O   1 
ATOM   1532 C  CB  . LEU   A 1 204 ? -12.19701 -27.22885 12.59265  1.000 46.40148  ? 204 LEU   A CB  1 
ATOM   1533 C  CG  . LEU   A 1 204 ? -13.55260 -27.51001 13.25227  1.000 44.89741  ? 204 LEU   A CG  1 
ATOM   1534 C  CD1 . LEU   A 1 204 ? -13.95530 -26.35638 14.16258  1.000 51.73796  ? 204 LEU   A CD1 1 
ATOM   1535 C  CD2 . LEU   A 1 204 ? -14.63715 -27.78338 12.22068  1.000 47.29670  ? 204 LEU   A CD2 1 
ATOM   1536 N  N   . GLN   A 1 205 ? -10.78482 -28.28055 14.90006  1.000 60.28367  ? 205 GLN   A N   1 
ATOM   1537 C  CA  . GLN   A 1 205 ? -10.65075 -28.77428 16.26502  1.000 63.54064  ? 205 GLN   A CA  1 
ATOM   1538 C  C   . GLN   A 1 205 ? -11.58928 -27.98154 17.16237  1.000 55.45623  ? 205 GLN   A C   1 
ATOM   1539 O  O   . GLN   A 1 205 ? -11.65427 -26.75246 17.06373  1.000 59.30132  ? 205 GLN   A O   1 
ATOM   1540 C  CB  . GLN   A 1 205 ? -9.20398  -28.66424 16.76448  1.000 49.94179  ? 205 GLN   A CB  1 
ATOM   1541 N  N   . ALA   A 1 206 ? -12.32420 -28.68746 18.01872  1.000 49.53889  ? 206 ALA   A N   1 
ATOM   1542 C  CA  . ALA   A 1 206 ? -13.23959 -28.06470 18.96384  1.000 60.33177  ? 206 ALA   A CA  1 
ATOM   1543 C  C   . ALA   A 1 206 ? -13.30142 -28.92031 20.21878  1.000 58.77381  ? 206 ALA   A C   1 
ATOM   1544 O  O   . ALA   A 1 206 ? -13.45328 -30.14263 20.13024  1.000 66.88530  ? 206 ALA   A O   1 
ATOM   1545 C  CB  . ALA   A 1 206 ? -14.64302 -27.90337 18.36607  1.000 60.72754  ? 206 ALA   A CB  1 
ATOM   1546 N  N   . ASN   A 1 207 ? -13.20186 -28.26915 21.38117  1.000 51.57062  ? 207 ASN   A N   1 
ATOM   1547 C  CA  . ASN   A 1 207 ? -13.16218 -28.96032 22.67488  1.000 78.31781  ? 207 ASN   A CA  1 
ATOM   1548 C  C   . ASN   A 1 207 ? -11.95402 -29.88871 22.76838  1.000 71.11620  ? 207 ASN   A C   1 
ATOM   1549 O  O   . ASN   A 1 207 ? -12.02480 -30.96422 23.36957  1.000 75.09999  ? 207 ASN   A O   1 
ATOM   1550 C  CB  . ASN   A 1 207 ? -14.45282 -29.74376 22.94790  1.000 65.69791  ? 207 ASN   A CB  1 
ATOM   1551 C  CG  . ASN   A 1 207 ? -15.69151 -28.98990 22.53724  1.000 67.87472  ? 207 ASN   A CG  1 
ATOM   1552 O  OD1 . ASN   A 1 207 ? -15.96826 -27.89320 23.03417  1.000 66.81990  ? 207 ASN   A OD1 1 
ATOM   1553 N  ND2 . ASN   A 1 207 ? -16.44239 -29.56690 21.60550  1.000 65.25528  ? 207 ASN   A ND2 1 
ATOM   1554 N  N   . GLY   A 1 208 ? -10.83831 -29.47264 22.16615  1.000 64.42160  ? 208 GLY   A N   1 
ATOM   1555 C  CA  . GLY   A 1 208 ? -9.62381  -30.26434 22.19799  1.000 58.71767  ? 208 GLY   A CA  1 
ATOM   1556 C  C   . GLY   A 1 208 ? -9.66068  -31.55087 21.40405  1.000 72.59383  ? 208 GLY   A C   1 
ATOM   1557 O  O   . GLY   A 1 208 ? -8.79055  -32.40322 21.59875  1.000 89.87953  ? 208 GLY   A O   1 
ATOM   1558 N  N   . GLN   A 1 209 ? -10.62010 -31.71633 20.50536  1.000 71.83064  ? 209 GLN   A N   1 
ATOM   1559 C  CA  . GLN   A 1 209 ? -10.77601 -32.93959 19.73548  1.000 61.69293  ? 209 GLN   A CA  1 
ATOM   1560 C  C   . GLN   A 1 209 ? -11.07611 -32.57939 18.28536  1.000 64.94232  ? 209 GLN   A C   1 
ATOM   1561 O  O   . GLN   A 1 209 ? -11.52274 -31.46592 17.99642  1.000 64.64373  ? 209 GLN   A O   1 
ATOM   1562 C  CB  . GLN   A 1 209 ? -11.90251 -33.80655 20.31357  1.000 66.78167  ? 209 GLN   A CB  1 
ATOM   1563 N  N   . PRO   A 1 210 ? -10.81637 -33.49870 17.35348  1.000 68.81515  ? 210 PRO   A N   1 
ATOM   1564 C  CA  . PRO   A 1 210 ? -11.24301 -33.27435 15.96191  1.000 64.74695  ? 210 PRO   A CA  1 
ATOM   1565 C  C   . PRO   A 1 210 ? -12.73552 -32.99038 15.87046  1.000 61.03936  ? 210 PRO   A C   1 
ATOM   1566 O  O   . PRO   A 1 210 ? -13.54864 -33.63896 16.53225  1.000 57.07037  ? 210 PRO   A O   1 
ATOM   1567 C  CB  . PRO   A 1 210 ? -10.89028 -34.59580 15.26618  1.000 57.00473  ? 210 PRO   A CB  1 
ATOM   1568 C  CG  . PRO   A 1 210 ? -9.77608  -35.17732 16.10006  1.000 52.11055  ? 210 PRO   A CG  1 
ATOM   1569 C  CD  . PRO   A 1 210 ? -10.07054 -34.76083 17.51671  1.000 59.80107  ? 210 PRO   A CD  1 
ATOM   1570 N  N   . ALA   A 1 211 ? -13.08941 -32.02310 15.02188  1.000 54.14574  ? 211 ALA   A N   1 
ATOM   1571 C  CA  . ALA   A 1 211 ? -14.47285 -31.64906 14.76894  1.000 46.84541  ? 211 ALA   A CA  1 
ATOM   1572 C  C   . ALA   A 1 211 ? -14.68316 -31.47220 13.26960  1.000 53.76067  ? 211 ALA   A C   1 
ATOM   1573 O  O   . ALA   A 1 211 ? -13.72677 -31.31244 12.50524  1.000 51.08161  ? 211 ALA   A O   1 
ATOM   1574 C  CB  . ALA   A 1 211 ? -14.85664 -30.36309 15.51491  1.000 51.29041  ? 211 ALA   A CB  1 
ATOM   1575 N  N   . TRP   A 1 212 ? -15.95071 -31.51613 12.84720  1.000 46.03753  ? 212 TRP   A N   1 
ATOM   1576 C  CA  . TRP   A 1 212 ? -16.28866 -31.41687 11.43180  1.000 40.31646  ? 212 TRP   A CA  1 
ATOM   1577 C  C   . TRP   A 1 212 ? -17.47056 -30.47972 11.22953  1.000 51.32673  ? 212 TRP   A C   1 
ATOM   1578 O  O   . TRP   A 1 212 ? -18.41098 -30.45866 12.02922  1.000 47.14174  ? 212 TRP   A O   1 
ATOM   1579 C  CB  . TRP   A 1 212 ? -16.60458 -32.79435 10.82242  1.000 62.01635  ? 212 TRP   A CB  1 
ATOM   1580 C  CG  . TRP   A 1 212 ? -15.41842 -33.69773 10.79286  1.000 52.19050  ? 212 TRP   A CG  1 
ATOM   1581 C  CD1 . TRP   A 1 212 ? -14.52218 -33.84460 9.77521   1.000 53.20785  ? 212 TRP   A CD1 1 
ATOM   1582 C  CD2 . TRP   A 1 212 ? -14.98092 -34.56315 11.84427  1.000 54.02653  ? 212 TRP   A CD2 1 
ATOM   1583 N  NE1 . TRP   A 1 212 ? -13.54773 -34.75018 10.12912  1.000 63.79341  ? 212 TRP   A NE1 1 
ATOM   1584 C  CE2 . TRP   A 1 212 ? -13.81062 -35.21087 11.39345  1.000 60.66269  ? 212 TRP   A CE2 1 
ATOM   1585 C  CE3 . TRP   A 1 212 ? -15.46950 -34.86080 13.12088  1.000 51.74338  ? 212 TRP   A CE3 1 
ATOM   1586 C  CZ2 . TRP   A 1 212 ? -13.12115 -36.14108 12.17565  1.000 65.28105  ? 212 TRP   A CZ2 1 
ATOM   1587 C  CZ3 . TRP   A 1 212 ? -14.78327 -35.78057 13.89635  1.000 66.28758  ? 212 TRP   A CZ3 1 
ATOM   1588 C  CH2 . TRP   A 1 212 ? -13.62088 -36.41045 13.42299  1.000 58.34743  ? 212 TRP   A CH2 1 
ATOM   1589 N  N   . ARG   A 1 213 ? -17.40437 -29.70061 10.15354  1.000 48.82255  ? 213 ARG   A N   1 
ATOM   1590 C  CA  . ARG   A 1 213 ? -18.48278 -28.82206 9.72473   1.000 39.87744  ? 213 ARG   A CA  1 
ATOM   1591 C  C   . ARG   A 1 213 ? -18.90404 -29.24236 8.32537   1.000 50.19885  ? 213 ARG   A C   1 
ATOM   1592 O  O   . ARG   A 1 213 ? -18.08728 -29.22508 7.39734   1.000 51.49080  ? 213 ARG   A O   1 
ATOM   1593 C  CB  . ARG   A 1 213 ? -18.03940 -27.35489 9.72869   1.000 49.07937  ? 213 ARG   A CB  1 
ATOM   1594 C  CG  . ARG   A 1 213 ? -19.09792 -26.39728 9.21853   1.000 47.91918  ? 213 ARG   A CG  1 
ATOM   1595 C  CD  . ARG   A 1 213 ? -18.72388 -24.95101 9.46749   1.000 55.08295  ? 213 ARG   A CD  1 
ATOM   1596 N  NE  . ARG   A 1 213 ? -17.51022 -24.55701 8.75923   1.000 50.04258  ? 213 ARG   A NE  1 
ATOM   1597 C  CZ  . ARG   A 1 213 ? -17.49348 -24.00860 7.55175   1.000 49.55459  ? 213 ARG   A CZ  1 
ATOM   1598 N  NH1 . ARG   A 1 213 ? -18.60547 -23.85071 6.85147   1.000 46.00607  ? 213 ARG   A NH1 1 
ATOM   1599 N  NH2 . ARG   A 1 213 ? -16.33410 -23.59079 7.04252   1.000 43.39855  ? 213 ARG   A NH2 1 
ATOM   1600 N  N   . VAL   A 1 214 ? -20.16977 -29.62124 8.17354   1.000 47.43096  ? 214 VAL   A N   1 
ATOM   1601 C  CA  . VAL   A 1 214 ? -20.70352 -30.10396 6.90610   1.000 36.96860  ? 214 VAL   A CA  1 
ATOM   1602 C  C   . VAL   A 1 214 ? -21.64988 -29.04703 6.36928   1.000 46.58666  ? 214 VAL   A C   1 
ATOM   1603 O  O   . VAL   A 1 214 ? -22.55187 -28.59023 7.08743   1.000 37.78848  ? 214 VAL   A O   1 
ATOM   1604 C  CB  . VAL   A 1 214 ? -21.40871 -31.46008 7.07003   1.000 50.71301  ? 214 VAL   A CB  1 
ATOM   1605 C  CG1 . VAL   A 1 214 ? -21.91137 -31.95584 5.72295   1.000 37.43351  ? 214 VAL   A CG1 1 
ATOM   1606 C  CG2 . VAL   A 1 214 ? -20.44450 -32.46309 7.69337   1.000 40.21871  ? 214 VAL   A CG2 1 
ATOM   1607 N  N   . VAL   A 1 215 ? -21.42624 -28.63444 5.12236   1.000 43.90992  ? 215 VAL   A N   1 
ATOM   1608 C  CA  . VAL   A 1 215 ? -22.15742 -27.52356 4.51773   1.000 44.22295  ? 215 VAL   A CA  1 
ATOM   1609 C  C   . VAL   A 1 215 ? -22.99483 -28.06659 3.37126   1.000 51.08666  ? 215 VAL   A C   1 
ATOM   1610 O  O   . VAL   A 1 215 ? -22.49874 -28.83431 2.53472   1.000 40.09552  ? 215 VAL   A O   1 
ATOM   1611 C  CB  . VAL   A 1 215 ? -21.21560 -26.41285 4.02418   1.000 46.12937  ? 215 VAL   A CB  1 
ATOM   1612 C  CG1 . VAL   A 1 215 ? -22.02771 -25.16525 3.64207   1.000 39.41287  ? 215 VAL   A CG1 1 
ATOM   1613 C  CG2 . VAL   A 1 215 ? -20.17576 -26.09253 5.08428   1.000 39.66770  ? 215 VAL   A CG2 1 
ATOM   1614 N  N   . LEU   A 1 216 ? -24.26112 -27.66961 3.33750   1.000 47.14533  ? 216 LEU   A N   1 
ATOM   1615 C  CA  . LEU   A 1 216 ? -25.17728 -28.10861 2.30233   1.000 35.66331  ? 216 LEU   A CA  1 
ATOM   1616 C  C   . LEU   A 1 216 ? -25.02184 -27.26674 1.04251   1.000 45.38463  ? 216 LEU   A C   1 
ATOM   1617 O  O   . LEU   A 1 216 ? -24.49218 -26.14418 1.06626   1.000 44.20307  ? 216 LEU   A O   1 
ATOM   1618 C  CB  . LEU   A 1 216 ? -26.61852 -28.01467 2.80128   1.000 37.05522  ? 216 LEU   A CB  1 
ATOM   1619 C  CG  . LEU   A 1 216 ? -27.03869 -29.13105 3.74386   1.000 47.76224  ? 216 LEU   A CG  1 
ATOM   1620 C  CD1 . LEU   A 1 216 ? -28.11316 -28.64322 4.71051   1.000 52.69331  ? 216 LEU   A CD1 1 
ATOM   1621 C  CD2 . LEU   A 1 216 ? -27.50669 -30.32605 2.91867   1.000 43.75158  ? 216 LEU   A CD2 1 
ATOM   1622 N  N   . GLY   A 1 217 ? -25.51811 -27.81350 -0.06989  1.000 36.01838  ? 217 GLY   A N   1 
ATOM   1623 C  CA  . GLY   A 1 217 ? -25.57795 -27.07859 -1.31363  1.000 37.43442  ? 217 GLY   A CA  1 
ATOM   1624 C  C   . GLY   A 1 217 ? -26.94651 -26.46896 -1.59465  1.000 55.35975  ? 217 GLY   A C   1 
ATOM   1625 O  O   . GLY   A 1 217 ? -27.98001 -26.94161 -1.12094  1.000 44.91375  ? 217 GLY   A O   1 
ATOM   1626 N  N   . ALA   A 1 218 ? -26.92785 -25.39581 -2.37780  1.000 43.29679  ? 218 ALA   A N   1 
ATOM   1627 C  CA  . ALA   A 1 218 ? -28.13761 -24.78423 -2.89996  1.000 44.57347  ? 218 ALA   A CA  1 
ATOM   1628 C  C   . ALA   A 1 218 ? -28.63541 -25.56299 -4.10544  1.000 46.25655  ? 218 ALA   A C   1 
ATOM   1629 O  O   . ALA   A 1 218 ? -27.85463 -26.18855 -4.82984  1.000 56.03093  ? 218 ALA   A O   1 
ATOM   1630 C  CB  . ALA   A 1 218 ? -27.87921 -23.32753 -3.31324  1.000 40.55351  ? 218 ALA   A CB  1 
ATOM   1631 N  N   . TRP   A 1 219 ? -29.94873 -25.50400 -4.32703  1.000 35.26576  ? 219 TRP   A N   1 
ATOM   1632 C  CA  . TRP   A 1 219 ? -30.58540 -26.20955 -5.44233  1.000 51.58047  ? 219 TRP   A CA  1 
ATOM   1633 C  C   . TRP   A 1 219 ? -30.59799 -25.26730 -6.64268  1.000 44.97878  ? 219 TRP   A C   1 
ATOM   1634 O  O   . TRP   A 1 219 ? -31.56476 -24.55445 -6.91221  1.000 58.88379  ? 219 TRP   A O   1 
ATOM   1635 C  CB  . TRP   A 1 219 ? -31.99178 -26.67390 -5.06144  1.000 42.43560  ? 219 TRP   A CB  1 
ATOM   1636 C  CG  . TRP   A 1 219 ? -32.03068 -27.73731 -3.97783  1.000 42.99398  ? 219 TRP   A CG  1 
ATOM   1637 C  CD1 . TRP   A 1 219 ? -31.30296 -27.76386 -2.81797  1.000 40.67482  ? 219 TRP   A CD1 1 
ATOM   1638 C  CD2 . TRP   A 1 219 ? -32.85781 -28.92734 -3.95934  1.000 42.71683  ? 219 TRP   A CD2 1 
ATOM   1639 N  NE1 . TRP   A 1 219 ? -31.62335 -28.89652 -2.08220  1.000 44.23697  ? 219 TRP   A NE1 1 
ATOM   1640 C  CE2 . TRP   A 1 219 ? -32.57412 -29.61974 -2.76127  1.000 34.26962  ? 219 TRP   A CE2 1 
ATOM   1641 C  CE3 . TRP   A 1 219 ? -33.80995 -29.46495 -4.83929  1.000 42.32770  ? 219 TRP   A CE3 1 
ATOM   1642 C  CZ2 . TRP   A 1 219 ? -33.20194 -30.82422 -2.42512  1.000 38.18150  ? 219 TRP   A CZ2 1 
ATOM   1643 C  CZ3 . TRP   A 1 219 ? -34.43881 -30.67109 -4.49986  1.000 44.53452  ? 219 TRP   A CZ3 1 
ATOM   1644 C  CH2 . TRP   A 1 219 ? -34.12573 -31.33459 -3.30444  1.000 34.03305  ? 219 TRP   A CH2 1 
ATOM   1645 N  N   . HIS   A 1 220 ? -29.48227 -25.25050 -7.36423  1.000 52.78228  ? 220 HIS   A N   1 
ATOM   1646 C  CA  . HIS   A 1 220 ? -29.35101 -24.36480 -8.51403  1.000 51.27021  ? 220 HIS   A CA  1 
ATOM   1647 C  C   . HIS   A 1 220 ? -29.59807 -25.13937 -9.79906  1.000 55.37808  ? 220 HIS   A C   1 
ATOM   1648 O  O   . HIS   A 1 220 ? -30.62671 -24.95476 -10.45613 1.000 71.19964  ? 220 HIS   A O   1 
ATOM   1649 C  CB  . HIS   A 1 220 ? -27.96902 -23.70832 -8.53468  1.000 62.52361  ? 220 HIS   A CB  1 
ATOM   1650 C  CG  . HIS   A 1 220 ? -27.85418 -22.57416 -9.50454  1.000 76.38792  ? 220 HIS   A CG  1 
ATOM   1651 N  ND1 . HIS   A 1 220 ? -26.91246 -22.54961 -10.51232 1.000 76.46806  ? 220 HIS   A ND1 1 
ATOM   1652 C  CD2 . HIS   A 1 220 ? -28.56760 -21.42981 -9.62854  1.000 71.47718  ? 220 HIS   A CD2 1 
ATOM   1653 C  CE1 . HIS   A 1 220 ? -27.04676 -21.43581 -11.21053 1.000 69.72017  ? 220 HIS   A CE1 1 
ATOM   1654 N  NE2 . HIS   A 1 220 ? -28.04629 -20.74010 -10.69689 1.000 76.83359  ? 220 HIS   A NE2 1 
ATOM   1655 N  N   . SER   A 1 221 ? -28.65889 -26.00630 -10.16889 1.000 64.46703  ? 221 SER   A N   1 
ATOM   1656 C  CA  . SER   A 1 221 ? -28.84458 -26.88166 -11.31505 1.000 58.32448  ? 221 SER   A CA  1 
ATOM   1657 C  C   . SER   A 1 221 ? -29.15004 -28.31216 -10.90803 1.000 61.99933  ? 221 SER   A C   1 
ATOM   1658 O  O   . SER   A 1 221 ? -29.77628 -29.04490 -11.68337 1.000 71.17074  ? 221 SER   A O   1 
ATOM   1659 C  CB  . SER   A 1 221 ? -27.59884 -26.86349 -12.20517 1.000 64.90108  ? 221 SER   A CB  1 
ATOM   1660 O  OG  . SER   A 1 221 ? -27.16298 -25.53363 -12.43354 1.000 78.91516  ? 221 SER   A OG  1 
ATOM   1661 N  N   . GLU   A 1 222 ? -28.74189 -28.71112 -9.70790  1.000 52.95683  ? 222 GLU   A N   1 
ATOM   1662 C  CA  . GLU   A 1 222 ? -28.98481 -30.04759 -9.19490  1.000 58.24242  ? 222 GLU   A CA  1 
ATOM   1663 C  C   . GLU   A 1 222 ? -29.37862 -29.93423 -7.73175  1.000 49.37328  ? 222 GLU   A C   1 
ATOM   1664 O  O   . GLU   A 1 222 ? -29.14072 -28.91323 -7.08243  1.000 44.06219  ? 222 GLU   A O   1 
ATOM   1665 C  CB  . GLU   A 1 222 ? -27.74653 -30.95438 -9.35830  1.000 51.47831  ? 222 GLU   A CB  1 
ATOM   1666 C  CG  . GLU   A 1 222 ? -27.43288 -31.29067 -10.81851 1.000 70.37687  ? 222 GLU   A CG  1 
ATOM   1667 C  CD  . GLU   A 1 222 ? -26.84215 -32.68847 -11.02695 1.000 75.40763  ? 222 GLU   A CD  1 
ATOM   1668 O  OE1 . GLU   A 1 222 ? -26.97176 -33.21581 -12.15817 1.000 61.37135  ? 222 GLU   A OE1 1 
ATOM   1669 O  OE2 . GLU   A 1 222 ? -26.22604 -33.24156 -10.08323 1.000 66.69232  ? 222 GLU   A OE2 1 
ATOM   1670 N  N   . GLY   A 1 223 ? -30.00524 -30.99130 -7.22286  1.000 40.12354  ? 223 GLY   A N   1 
ATOM   1671 C  CA  . GLY   A 1 223 ? -30.30422 -31.06360 -5.81132  1.000 46.14657  ? 223 GLY   A CA  1 
ATOM   1672 C  C   . GLY   A 1 223 ? -29.10180 -31.48389 -4.97965  1.000 40.18021  ? 223 GLY   A C   1 
ATOM   1673 O  O   . GLY   A 1 223 ? -28.09982 -31.98161 -5.47889  1.000 39.71235  ? 223 GLY   A O   1 
ATOM   1674 N  N   . SER   A 1 224 ? -29.23419 -31.28562 -3.67107  1.000 42.73072  ? 224 SER   A N   1 
ATOM   1675 C  CA  . SER   A 1 224 ? -28.18728 -31.55735 -2.69776  1.000 33.91125  ? 224 SER   A CA  1 
ATOM   1676 C  C   . SER   A 1 224 ? -28.84786 -32.00102 -1.40248  1.000 51.10433  ? 224 SER   A C   1 
ATOM   1677 O  O   . SER   A 1 224 ? -29.89781 -31.46725 -1.03122  1.000 40.26773  ? 224 SER   A O   1 
ATOM   1678 C  CB  . SER   A 1 224 ? -27.33568 -30.31101 -2.45086  1.000 38.13044  ? 224 SER   A CB  1 
ATOM   1679 O  OG  . SER   A 1 224 ? -26.21904 -30.60270 -1.63636  1.000 58.83623  ? 224 SER   A OG  1 
ATOM   1680 N  N   . MET   A 1 225 ? -28.24447 -32.98555 -0.73120  1.000 42.87270  ? 225 MET   A N   1 
ATOM   1681 C  CA  . MET   A 1 225 ? -28.69254 -33.38500 0.59632   1.000 34.35912  ? 225 MET   A CA  1 
ATOM   1682 C  C   . MET   A 1 225 ? -27.50629 -33.94524 1.36968   1.000 45.25719  ? 225 MET   A C   1 
ATOM   1683 O  O   . MET   A 1 225 ? -26.53510 -34.44090 0.78788   1.000 39.71923  ? 225 MET   A O   1 
ATOM   1684 C  CB  . MET   A 1 225 ? -29.80476 -34.44458 0.55083   1.000 44.99797  ? 225 MET   A CB  1 
ATOM   1685 C  CG  . MET   A 1 225 ? -29.33429 -35.83933 0.09220   1.000 39.59658  ? 225 MET   A CG  1 
ATOM   1686 S  SD  . MET   A 1 225 ? -30.61328 -37.14136 0.10652   1.000 51.59019  ? 225 MET   A SD  1 
ATOM   1687 C  CE  . MET   A 1 225 ? -31.13801 -37.17651 -1.59670  1.000 44.27306  ? 225 MET   A CE  1 
ATOM   1688 N  N   . VAL   A 1 226 ? -27.59771 -33.87152 2.69614   1.000 43.19008  ? 226 VAL   A N   1 
ATOM   1689 C  CA  . VAL   A 1 226 ? -26.72870 -34.63095 3.58860   1.000 37.35554  ? 226 VAL   A CA  1 
ATOM   1690 C  C   . VAL   A 1 226 ? -27.55705 -35.76165 4.19783   1.000 45.82381  ? 226 VAL   A C   1 
ATOM   1691 O  O   . VAL   A 1 226 ? -28.66961 -35.52961 4.69260   1.000 40.38399  ? 226 VAL   A O   1 
ATOM   1692 C  CB  . VAL   A 1 226 ? -26.11053 -33.73271 4.67390   1.000 37.31994  ? 226 VAL   A CB  1 
ATOM   1693 C  CG1 . VAL   A 1 226 ? -25.41655 -34.56835 5.74162   1.000 38.43916  ? 226 VAL   A CG1 1 
ATOM   1694 C  CG2 . VAL   A 1 226 ? -25.12370 -32.73872 4.04847   1.000 41.24551  ? 226 VAL   A CG2 1 
ATOM   1695 N  N   . LYS   A 1 227 ? -27.04071 -36.98656 4.11406   1.000 42.37335  ? 227 LYS   A N   1 
ATOM   1696 C  CA  . LYS   A 1 227 ? -27.63981 -38.15923 4.74262   1.000 43.03686  ? 227 LYS   A CA  1 
ATOM   1697 C  C   . LYS   A 1 227 ? -26.71737 -38.64391 5.84897   1.000 51.41190  ? 227 LYS   A C   1 
ATOM   1698 O  O   . LYS   A 1 227 ? -25.52578 -38.88350 5.60772   1.000 47.93039  ? 227 LYS   A O   1 
ATOM   1699 C  CB  . LYS   A 1 227 ? -27.86159 -39.28787 3.73680   1.000 36.16991  ? 227 LYS   A CB  1 
ATOM   1700 C  CG  . LYS   A 1 227 ? -28.59462 -40.48712 4.31642   1.000 53.18786  ? 227 LYS   A CG  1 
ATOM   1701 C  CD  . LYS   A 1 227 ? -28.22133 -41.76606 3.60007   1.000 50.60217  ? 227 LYS   A CD  1 
ATOM   1702 C  CE  . LYS   A 1 227 ? -29.12147 -42.00601 2.41529   1.000 55.29386  ? 227 LYS   A CE  1 
ATOM   1703 N  NZ  . LYS   A 1 227 ? -29.51877 -43.43975 2.31748   1.000 56.08076  ? 227 LYS   A NZ  1 
ATOM   1704 N  N   . VAL   A 1 228 ? -27.25890 -38.77742 7.05644   1.000 44.21935  ? 228 VAL   A N   1 
ATOM   1705 C  CA  . VAL   A 1 228 ? -26.50304 -39.26796 8.20375   1.000 46.54012  ? 228 VAL   A CA  1 
ATOM   1706 C  C   . VAL   A 1 228 ? -27.03739 -40.64835 8.55649   1.000 48.77866  ? 228 VAL   A C   1 
ATOM   1707 O  O   . VAL   A 1 228 ? -28.23281 -40.81344 8.82458   1.000 43.20774  ? 228 VAL   A O   1 
ATOM   1708 C  CB  . VAL   A 1 228 ? -26.58715 -38.31329 9.40613   1.000 47.81921  ? 228 VAL   A CB  1 
ATOM   1709 C  CG1 . VAL   A 1 228 ? -25.77988 -38.86377 10.58493  1.000 35.42677  ? 228 VAL   A CG1 1 
ATOM   1710 C  CG2 . VAL   A 1 228 ? -26.09789 -36.92102 9.01551   1.000 38.39757  ? 228 VAL   A CG2 1 
ATOM   1711 N  N   . THR   A 1 229 ? -26.16445 -41.63888 8.52617   1.000 53.97655  ? 229 THR   A N   1 
ATOM   1712 C  CA  . THR   A 1 229 ? -26.44606 -42.98627 8.98368   1.000 49.61389  ? 229 THR   A CA  1 
ATOM   1713 C  C   . THR   A 1 229 ? -25.66371 -43.26190 10.25813  1.000 44.03437  ? 229 THR   A C   1 
ATOM   1714 O  O   . THR   A 1 229 ? -24.82605 -42.44915 10.67572  1.000 43.81144  ? 229 THR   A O   1 
ATOM   1715 C  CB  . THR   A 1 229 ? -26.08307 -44.00681 7.89173   1.000 50.25576  ? 229 THR   A CB  1 
ATOM   1716 O  OG1 . THR   A 1 229 ? -24.65690 -44.09879 7.77099   1.000 55.66445  ? 229 THR   A OG1 1 
ATOM   1717 C  CG2 . THR   A 1 229 ? -26.67873 -43.59605 6.55304   1.000 38.80633  ? 229 THR   A CG2 1 
ATOM   1718 N  N   . PRO   A 1 230 ? -25.92030 -44.38319 10.93530  1.000 50.79301  ? 230 PRO   A N   1 
ATOM   1719 C  CA  . PRO   A 1 230 ? -25.03929 -44.77472 12.04993  1.000 57.21338  ? 230 PRO   A CA  1 
ATOM   1720 C  C   . PRO   A 1 230 ? -23.58505 -45.01770 11.63555  1.000 56.26071  ? 230 PRO   A C   1 
ATOM   1721 O  O   . PRO   A 1 230 ? -22.69520 -44.96835 12.49388  1.000 52.54038  ? 230 PRO   A O   1 
ATOM   1722 C  CB  . PRO   A 1 230 ? -25.69594 -46.05612 12.59311  1.000 59.20342  ? 230 PRO   A CB  1 
ATOM   1723 C  CG  . PRO   A 1 230 ? -26.74872 -46.43814 11.59549  1.000 45.98331  ? 230 PRO   A CG  1 
ATOM   1724 C  CD  . PRO   A 1 230 ? -27.15941 -45.18044 10.91656  1.000 43.35343  ? 230 PRO   A CD  1 
ATOM   1725 N  N   . ASP   A 1 231 ? -23.30730 -45.23600 10.34974  1.000 46.01777  ? 231 ASP   A N   1 
ATOM   1726 C  CA  . ASP   A 1 231 ? -21.96563 -45.59471 9.90158   1.000 50.56333  ? 231 ASP   A CA  1 
ATOM   1727 C  C   . ASP   A 1 231 ? -21.19211 -44.45615 9.25206   1.000 64.67766  ? 231 ASP   A C   1 
ATOM   1728 O  O   . ASP   A 1 231 ? -19.95756 -44.48462 9.27195   1.000 61.45188  ? 231 ASP   A O   1 
ATOM   1729 C  CB  . ASP   A 1 231 ? -22.03902 -46.75450 8.90910   1.000 53.36996  ? 231 ASP   A CB  1 
ATOM   1730 C  CG  . ASP   A 1 231 ? -22.48151 -48.03679 9.56018   1.000 67.67579  ? 231 ASP   A CG  1 
ATOM   1731 O  OD1 . ASP   A 1 231 ? -22.14269 -48.23449 10.74927  1.000 63.42705  ? 231 ASP   A OD1 1 
ATOM   1732 O  OD2 . ASP   A 1 231 ? -23.16559 -48.84083 8.88498   1.000 82.01628  ? 231 ASP   A OD2 1 
ATOM   1733 N  N   . ASP   A 1 232 ? -21.86153 -43.46426 8.66649   1.000 52.02264  ? 232 ASP   A N   1 
ATOM   1734 C  CA  . ASP   A 1 232 ? -21.14518 -42.44934 7.90271   1.000 50.60832  ? 232 ASP   A CA  1 
ATOM   1735 C  C   . ASP   A 1 232 ? -21.98436 -41.17735 7.79224   1.000 45.04161  ? 232 ASP   A C   1 
ATOM   1736 O  O   . ASP   A 1 232 ? -23.12373 -41.10669 8.26158   1.000 49.25843  ? 232 ASP   A O   1 
ATOM   1737 C  CB  . ASP   A 1 232 ? -20.74665 -42.98578 6.51941   1.000 51.41644  ? 232 ASP   A CB  1 
ATOM   1738 C  CG  . ASP   A 1 232 ? -21.92898 -43.53988 5.72584   1.000 52.99290  ? 232 ASP   A CG  1 
ATOM   1739 O  OD1 . ASP   A 1 232 ? -23.00443 -42.90088 5.68955   1.000 53.72008  ? 232 ASP   A OD1 1 
ATOM   1740 O  OD2 . ASP   A 1 232 ? -21.76846 -44.60866 5.10126   1.000 59.68326  ? 232 ASP   A OD2 1 
ATOM   1741 N  N   . VAL   A 1 233 ? -21.38535 -40.15811 7.18371   1.000 48.21376  ? 233 VAL   A N   1 
ATOM   1742 C  CA  . VAL   A 1 233 ? -22.06007 -38.92039 6.80465   1.000 46.95517  ? 233 VAL   A CA  1 
ATOM   1743 C  C   . VAL   A 1 233 ? -21.86785 -38.77021 5.30201   1.000 49.20796  ? 233 VAL   A C   1 
ATOM   1744 O  O   . VAL   A 1 233 ? -20.75266 -38.95744 4.79665   1.000 40.19008  ? 233 VAL   A O   1 
ATOM   1745 C  CB  . VAL   A 1 233 ? -21.49947 -37.70322 7.57165   1.000 54.82511  ? 233 VAL   A CB  1 
ATOM   1746 C  CG1 . VAL   A 1 233 ? -22.23278 -36.41077 7.18053   1.000 42.57657  ? 233 VAL   A CG1 1 
ATOM   1747 C  CG2 . VAL   A 1 233 ? -21.59552 -37.92471 9.08190   1.000 49.78706  ? 233 VAL   A CG2 1 
ATOM   1748 N  N   . GLU   A 1 234 ? -22.95040 -38.46897 4.58653   1.000 47.30615  ? 234 GLU   A N   1 
ATOM   1749 C  CA  . GLU   A 1 234 ? -22.94837 -38.49135 3.12835   1.000 46.53332  ? 234 GLU   A CA  1 
ATOM   1750 C  C   . GLU   A 1 234 ? -23.44439 -37.16605 2.56826   1.000 42.81330  ? 234 GLU   A C   1 
ATOM   1751 O  O   . GLU   A 1 234 ? -24.55781 -36.73123 2.88384   1.000 40.73713  ? 234 GLU   A O   1 
ATOM   1752 C  CB  . GLU   A 1 234 ? -23.82237 -39.63589 2.60104   1.000 45.89908  ? 234 GLU   A CB  1 
ATOM   1753 C  CG  . GLU   A 1 234 ? -23.56485 -40.97186 3.28758   1.000 45.71798  ? 234 GLU   A CG  1 
ATOM   1754 C  CD  . GLU   A 1 234 ? -24.41114 -42.10025 2.72971   1.000 54.74409  ? 234 GLU   A CD  1 
ATOM   1755 O  OE1 . GLU   A 1 234 ? -25.10315 -41.89196 1.71047   1.000 64.04007  ? 234 GLU   A OE1 1 
ATOM   1756 O  OE2 . GLU   A 1 234 ? -24.38165 -43.20775 3.30659   1.000 63.39251  ? 234 GLU   A OE2 1 
ATOM   1757 N  N   . LEU   A 1 235 ? -22.62845 -36.53838 1.72605   1.000 36.84318  ? 235 LEU   A N   1 
ATOM   1758 C  CA  . LEU   A 1 235 ? -23.03777 -35.37052 0.95013   1.000 37.50175  ? 235 LEU   A CA  1 
ATOM   1759 C  C   . LEU   A 1 235 ? -23.34283 -35.84859 -0.46595  1.000 48.63966  ? 235 LEU   A C   1 
ATOM   1760 O  O   . LEU   A 1 235 ? -22.45762 -36.38251 -1.14543  1.000 48.53694  ? 235 LEU   A O   1 
ATOM   1761 C  CB  . LEU   A 1 235 ? -21.94635 -34.29807 0.95422   1.000 43.29417  ? 235 LEU   A CB  1 
ATOM   1762 C  CG  . LEU   A 1 235 ? -22.12809 -32.98581 0.18125   1.000 42.07179  ? 235 LEU   A CG  1 
ATOM   1763 C  CD1 . LEU   A 1 235 ? -23.36428 -32.19238 0.64634   1.000 43.88908  ? 235 LEU   A CD1 1 
ATOM   1764 C  CD2 . LEU   A 1 235 ? -20.85363 -32.15465 0.31127   1.000 44.95160  ? 235 LEU   A CD2 1 
ATOM   1765 N  N   . ILE   A 1 236 ? -24.59005 -35.67001 -0.90060  1.000 44.35841  ? 236 ILE   A N   1 
ATOM   1766 C  CA  . ILE   A 1 236 ? -25.13058 -36.33039 -2.08506  1.000 46.39374  ? 236 ILE   A CA  1 
ATOM   1767 C  C   . ILE   A 1 236 ? -25.71425 -35.28194 -3.02426  1.000 54.74430  ? 236 ILE   A C   1 
ATOM   1768 O  O   . ILE   A 1 236 ? -26.55607 -34.47277 -2.61292  1.000 51.50829  ? 236 ILE   A O   1 
ATOM   1769 C  CB  . ILE   A 1 236 ? -26.20410 -37.36761 -1.69789  1.000 55.63148  ? 236 ILE   A CB  1 
ATOM   1770 C  CG1 . ILE   A 1 236 ? -25.59478 -38.47432 -0.81863  1.000 45.79664  ? 236 ILE   A CG1 1 
ATOM   1771 C  CG2 . ILE   A 1 236 ? -26.91313 -37.92629 -2.94048  1.000 41.58931  ? 236 ILE   A CG2 1 
ATOM   1772 C  CD1 . ILE   A 1 236 ? -26.61376 -39.40304 -0.21163  1.000 49.63070  ? 236 ILE   A CD1 1 
ATOM   1773 N  N   . HIS   A 1 237 ? -25.28351 -35.30638 -4.28665  1.000 40.73078  ? 237 HIS   A N   1 
ATOM   1774 C  CA  . HIS   A 1 237 ? -25.84979 -34.45055 -5.32298  1.000 49.21144  ? 237 HIS   A CA  1 
ATOM   1775 C  C   . HIS   A 1 237 ? -26.54989 -35.30379 -6.36914  1.000 52.93967  ? 237 HIS   A C   1 
ATOM   1776 O  O   . HIS   A 1 237 ? -26.04533 -36.36576 -6.74565  1.000 56.55443  ? 237 HIS   A O   1 
ATOM   1777 C  CB  . HIS   A 1 237 ? -24.77880 -33.58752 -5.97671  1.000 42.63509  ? 237 HIS   A CB  1 
ATOM   1778 C  CG  . HIS   A 1 237 ? -24.35707 -32.43076 -5.13052  1.000 62.02543  ? 237 HIS   A CG  1 
ATOM   1779 N  ND1 . HIS   A 1 237 ? -23.80829 -32.59220 -3.87600  1.000 58.98457  ? 237 HIS   A ND1 1 
ATOM   1780 C  CD2 . HIS   A 1 237 ? -24.43426 -31.09583 -5.34057  1.000 51.78419  ? 237 HIS   A CD2 1 
ATOM   1781 C  CE1 . HIS   A 1 237 ? -23.55319 -31.40709 -3.35510  1.000 56.71055  ? 237 HIS   A CE1 1 
ATOM   1782 N  NE2 . HIS   A 1 237 ? -23.92305 -30.48264 -4.22353  1.000 59.08596  ? 237 HIS   A NE2 1 
ATOM   1783 N  N   . PHE   A 1 238 ? -27.69911 -34.82690 -6.84482  1.000 49.54904  ? 238 PHE   A N   1 
ATOM   1784 C  CA  . PHE   A 1 238 ? -28.58783 -35.61412 -7.69415  1.000 56.27098  ? 238 PHE   A CA  1 
ATOM   1785 C  C   . PHE   A 1 238 ? -29.34234 -34.66069 -8.61530  1.000 52.79490  ? 238 PHE   A C   1 
ATOM   1786 O  O   . PHE   A 1 238 ? -29.49899 -33.48408 -8.29716  1.000 52.21965  ? 238 PHE   A O   1 
ATOM   1787 C  CB  . PHE   A 1 238 ? -29.57472 -36.44593 -6.85619  1.000 51.16711  ? 238 PHE   A CB  1 
ATOM   1788 C  CG  . PHE   A 1 238 ? -30.38278 -35.63004 -5.87270  1.000 55.58896  ? 238 PHE   A CG  1 
ATOM   1789 C  CD1 . PHE   A 1 238 ? -29.83610 -35.23901 -4.65230  1.000 47.37527  ? 238 PHE   A CD1 1 
ATOM   1790 C  CD2 . PHE   A 1 238 ? -31.67990 -35.25116 -6.17134  1.000 46.07879  ? 238 PHE   A CD2 1 
ATOM   1791 C  CE1 . PHE   A 1 238 ? -30.56138 -34.48354 -3.75530  1.000 43.80259  ? 238 PHE   A CE1 1 
ATOM   1792 C  CE2 . PHE   A 1 238 ? -32.41674 -34.48874 -5.28005  1.000 48.40938  ? 238 PHE   A CE2 1 
ATOM   1793 C  CZ  . PHE   A 1 238 ? -31.86147 -34.11029 -4.06647  1.000 47.95040  ? 238 PHE   A CZ  1 
ATOM   1794 N  N   . PRO   A 1 239 ? -29.81116 -35.14986 -9.76337  1.000 61.82211  ? 239 PRO   A N   1 
ATOM   1795 C  CA  . PRO   A 1 239 ? -30.62537 -34.29770 -10.64593 1.000 61.84618  ? 239 PRO   A CA  1 
ATOM   1796 C  C   . PRO   A 1 239 ? -32.03689 -34.08568 -10.10877 1.000 54.16058  ? 239 PRO   A C   1 
ATOM   1797 O  O   . PRO   A 1 239 ? -32.55182 -34.85787 -9.29899  1.000 44.25522  ? 239 PRO   A O   1 
ATOM   1798 C  CB  . PRO   A 1 239 ? -30.64472 -35.07864 -11.96599 1.000 56.46710  ? 239 PRO   A CB  1 
ATOM   1799 C  CG  . PRO   A 1 239 ? -30.42208 -36.49099 -11.56398 1.000 60.28591  ? 239 PRO   A CG  1 
ATOM   1800 C  CD  . PRO   A 1 239 ? -29.49348 -36.44512 -10.38255 1.000 49.12769  ? 239 PRO   A CD  1 
ATOM   1801 N  N   . PHE   A 1 240 ? -32.66325 -32.99486 -10.56463 1.000 57.04076  ? 240 PHE   A N   1 
ATOM   1802 C  CA  . PHE   A 1 240 ? -34.01452 -32.68252 -10.10540 1.000 54.07340  ? 240 PHE   A CA  1 
ATOM   1803 C  C   . PHE   A 1 240 ? -34.99987 -33.72726 -10.59608 1.000 53.99419  ? 240 PHE   A C   1 
ATOM   1804 O  O   . PHE   A 1 240 ? -35.70018 -34.36972 -9.80350  1.000 63.11700  ? 240 PHE   A O   1 
ATOM   1805 C  CB  . PHE   A 1 240 ? -34.46875 -31.30063 -10.59586 1.000 59.38763  ? 240 PHE   A CB  1 
ATOM   1806 C  CG  . PHE   A 1 240 ? -33.73459 -30.14961 -9.98060  1.000 58.47343  ? 240 PHE   A CG  1 
ATOM   1807 C  CD1 . PHE   A 1 240 ? -33.19369 -30.24872 -8.70639  1.000 61.25609  ? 240 PHE   A CD1 1 
ATOM   1808 C  CD2 . PHE   A 1 240 ? -33.62520 -28.94445 -10.66670 1.000 58.24128  ? 240 PHE   A CD2 1 
ATOM   1809 C  CE1 . PHE   A 1 240 ? -32.52290 -29.17212 -8.13404  1.000 54.43474  ? 240 PHE   A CE1 1 
ATOM   1810 C  CE2 . PHE   A 1 240 ? -32.95081 -27.86074 -10.10807 1.000 62.78107  ? 240 PHE   A CE2 1 
ATOM   1811 C  CZ  . PHE   A 1 240 ? -32.39704 -27.97409 -8.83727  1.000 54.80590  ? 240 PHE   A CZ  1 
ATOM   1812 N  N   . LEU   A 1 241 ? -35.08640 -33.88812 -11.90828 1.000 63.23454  ? 241 LEU   A N   1 
ATOM   1813 C  CA  . LEU   A 1 241 ? -36.08019 -34.75084 -12.52302 1.000 74.89880  ? 241 LEU   A CA  1 
ATOM   1814 C  C   . LEU   A 1 241 ? -35.44306 -36.05889 -12.97934 1.000 67.00601  ? 241 LEU   A C   1 
ATOM   1815 O  O   . LEU   A 1 241 ? -34.22073 -36.17674 -13.09381 1.000 66.15816  ? 241 LEU   A O   1 
ATOM   1816 C  CB  . LEU   A 1 241 ? -36.74493 -34.03710 -13.70491 1.000 64.60672  ? 241 LEU   A CB  1 
ATOM   1817 C  CG  . LEU   A 1 241 ? -37.87757 -33.04193 -13.38386 1.000 85.02186  ? 241 LEU   A CG  1 
ATOM   1818 C  CD1 . LEU   A 1 241 ? -38.89366 -33.59630 -12.37226 1.000 62.76963  ? 241 LEU   A CD1 1 
ATOM   1819 C  CD2 . LEU   A 1 241 ? -37.29562 -31.72555 -12.89549 1.000 59.52231  ? 241 LEU   A CD2 1 
ATOM   1820 N  N   . GLU   A 1 242 ? -36.29901 -37.04673 -13.23952 1.000 91.05415  ? 242 GLU   A N   1 
ATOM   1821 C  CA  . GLU   A 1 242 ? -35.85694 -38.35868 -13.70241 1.000 83.64753  ? 242 GLU   A CA  1 
ATOM   1822 C  C   . GLU   A 1 242 ? -35.25565 -38.22449 -15.09608 1.000 84.23536  ? 242 GLU   A C   1 
ATOM   1823 O  O   . GLU   A 1 242 ? -35.97565 -37.99602 -16.07322 1.000 82.14485  ? 242 GLU   A O   1 
ATOM   1824 C  CB  . GLU   A 1 242 ? -37.02771 -39.33781 -13.69918 1.000 83.11423  ? 242 GLU   A CB  1 
ATOM   1825 N  N   . GLU   A 1 243 ? -33.93430 -38.35736 -15.19004 1.000 102.12685 ? 243 GLU   A N   1 
ATOM   1826 C  CA  . GLU   A 1 243 ? -33.23047 -38.23759 -16.46579 1.000 111.43221 ? 243 GLU   A CA  1 
ATOM   1827 C  C   . GLU   A 1 243 ? -33.24709 -39.59146 -17.16149 1.000 115.27108 ? 243 GLU   A C   1 
ATOM   1828 O  O   . GLU   A 1 243 ? -32.45828 -40.48242 -16.83264 1.000 112.61305 ? 243 GLU   A O   1 
ATOM   1829 C  CB  . GLU   A 1 243 ? -31.80423 -37.74111 -16.25586 1.000 107.14461 ? 243 GLU   A CB  1 
ATOM   1830 C  CG  . GLU   A 1 243 ? -31.72210 -36.38094 -15.60222 1.000 96.01224  ? 243 GLU   A CG  1 
ATOM   1831 C  CD  . GLU   A 1 243 ? -30.72585 -35.47908 -16.28688 1.000 102.39965 ? 243 GLU   A CD  1 
ATOM   1832 O  OE1 . GLU   A 1 243 ? -29.53028 -35.84178 -16.33694 1.000 111.13502 ? 243 GLU   A OE1 1 
ATOM   1833 O  OE2 . GLU   A 1 243 ? -31.14334 -34.40825 -16.78074 1.000 114.53587 ? 243 GLU   A OE2 1 
ATOM   1834 N  N   . ASN   A 1 244 ? -34.14606 -39.74150 -18.13488 1.000 117.30355 ? 244 ASN   A N   1 
ATOM   1835 C  CA  . ASN   A 1 244 ? -34.26878 -40.99571 -18.86729 1.000 112.12515 ? 244 ASN   A CA  1 
ATOM   1836 C  C   . ASN   A 1 244 ? -33.04362 -41.24206 -19.73645 1.000 112.73513 ? 244 ASN   A C   1 
ATOM   1837 O  O   . ASN   A 1 244 ? -32.51165 -40.32583 -20.37062 1.000 106.55584 ? 244 ASN   A O   1 
ATOM   1838 C  CB  . ASN   A 1 244 ? -35.52043 -40.98337 -19.73839 1.000 108.16515 ? 244 ASN   A CB  1 
ATOM   1839 C  CG  . ASN   A 1 244 ? -36.76924 -40.72707 -18.94115 1.000 114.91475 ? 244 ASN   A CG  1 
ATOM   1840 O  OD1 . ASN   A 1 244 ? -36.95723 -41.29377 -17.86518 1.000 117.81396 ? 244 ASN   A OD1 1 
ATOM   1841 N  ND2 . ASN   A 1 244 ? -37.63445 -39.86475 -19.45930 1.000 121.76778 ? 244 ASN   A ND2 1 
ATOM   1842 N  N   . LEU   A 1 245 ? -32.59867 -42.49273 -19.76805 1.000 114.73183 ? 245 LEU   A N   1 
ATOM   1843 C  CA  . LEU   A 1 245 ? -31.45068 -42.84945 -20.58193 1.000 99.55889  ? 245 LEU   A CA  1 
ATOM   1844 C  C   . LEU   A 1 245 ? -31.89221 -43.07284 -22.02261 1.000 81.93966  ? 245 LEU   A C   1 
ATOM   1845 O  O   . LEU   A 1 245 ? -32.95292 -43.64605 -22.28592 1.000 72.60112  ? 245 LEU   A O   1 
ATOM   1846 C  CB  . LEU   A 1 245 ? -30.76121 -44.09897 -20.02334 1.000 84.60611  ? 245 LEU   A CB  1 
ATOM   1847 C  CG  . LEU   A 1 245 ? -29.65558 -44.76039 -20.85328 1.000 68.55418  ? 245 LEU   A CG  1 
ATOM   1848 N  N   . TYR   A 1 246 ? -31.09299 -42.56354 -22.95168 1.000 74.18601  ? 246 TYR   A N   1 
ATOM   1849 C  CA  . TYR   A 1 246 ? -31.23064 -42.86475 -24.36470 1.000 63.11623  ? 246 TYR   A CA  1 
ATOM   1850 C  C   . TYR   A 1 246 ? -29.82919 -42.96695 -24.94556 1.000 69.48095  ? 246 TYR   A C   1 
ATOM   1851 O  O   . TYR   A 1 246 ? -28.87222 -42.42815 -24.38532 1.000 83.57707  ? 246 TYR   A O   1 
ATOM   1852 C  CB  . TYR   A 1 246 ? -32.07456 -41.80980 -25.09797 1.000 60.55951  ? 246 TYR   A CB  1 
ATOM   1853 C  CG  . TYR   A 1 246 ? -31.40121 -40.46636 -25.28257 1.000 83.43547  ? 246 TYR   A CG  1 
ATOM   1854 C  CD1 . TYR   A 1 246 ? -31.50390 -39.47694 -24.30842 1.000 87.32401  ? 246 TYR   A CD1 1 
ATOM   1855 C  CD2 . TYR   A 1 246 ? -30.68256 -40.17629 -26.44251 1.000 80.12159  ? 246 TYR   A CD2 1 
ATOM   1856 C  CE1 . TYR   A 1 246 ? -30.89425 -38.24354 -24.47389 1.000 86.61560  ? 246 TYR   A CE1 1 
ATOM   1857 C  CE2 . TYR   A 1 246 ? -30.07011 -38.94387 -26.61799 1.000 86.03529  ? 246 TYR   A CE2 1 
ATOM   1858 C  CZ  . TYR   A 1 246 ? -30.18260 -37.98184 -25.63083 1.000 90.20863  ? 246 TYR   A CZ  1 
ATOM   1859 O  OH  . TYR   A 1 246 ? -29.58129 -36.75528 -25.80058 1.000 91.78067  ? 246 TYR   A OH  1 
ATOM   1860 N  N   . PHE   A 1 247 ? -29.70496 -43.67937 -26.05601 1.000 59.44625  ? 247 PHE   A N   1 
ATOM   1861 C  CA  . PHE   A 1 247 ? -28.39914 -44.00831 -26.60364 1.000 65.41614  ? 247 PHE   A CA  1 
ATOM   1862 C  C   . PHE   A 1 247 ? -28.11445 -43.18756 -27.85516 1.000 64.72652  ? 247 PHE   A C   1 
ATOM   1863 O  O   . PHE   A 1 247 ? -28.99418 -42.99297 -28.69854 1.000 66.99007  ? 247 PHE   A O   1 
ATOM   1864 C  CB  . PHE   A 1 247 ? -28.30555 -45.50581 -26.92116 1.000 58.78831  ? 247 PHE   A CB  1 
ATOM   1865 C  CG  . PHE   A 1 247 ? -28.53054 -46.39802 -25.72815 1.000 57.46212  ? 247 PHE   A CG  1 
ATOM   1866 C  CD1 . PHE   A 1 247 ? -27.71069 -46.30747 -24.61127 1.000 55.93691  ? 247 PHE   A CD1 1 
ATOM   1867 C  CD2 . PHE   A 1 247 ? -29.55276 -47.33941 -25.72860 1.000 57.95384  ? 247 PHE   A CD2 1 
ATOM   1868 C  CE1 . PHE   A 1 247 ? -27.90838 -47.13110 -23.51077 1.000 54.90854  ? 247 PHE   A CE1 1 
ATOM   1869 C  CE2 . PHE   A 1 247 ? -29.75738 -48.16767 -24.63223 1.000 56.99602  ? 247 PHE   A CE2 1 
ATOM   1870 C  CZ  . PHE   A 1 247 ? -28.92627 -48.06175 -23.51986 1.000 55.46281  ? 247 PHE   A CZ  1 
ATOM   1871 N  N   . GLN   A 1 248 ? -26.88140 -42.69597 -27.95828 1.000 82.67939  ? 248 GLN   A N   1 
ATOM   1872 C  CA  . GLN   A 1 248 ? -26.36716 -42.09144 -29.17816 1.000 76.90237  ? 248 GLN   A CA  1 
ATOM   1873 C  C   . GLN   A 1 248 ? -25.43728 -43.08385 -29.85672 1.000 70.17219  ? 248 GLN   A C   1 
ATOM   1874 O  O   . GLN   A 1 248 ? -24.63795 -43.74788 -29.19264 1.000 81.87800  ? 248 GLN   A O   1 
ATOM   1875 C  CB  . GLN   A 1 248 ? -25.61925 -40.79073 -28.88268 1.000 81.78948  ? 248 GLN   A CB  1 
ATOM   1876 N  N   . SER   A 1 249 ? -25.54114 -43.18269 -31.18166 1.000 68.54142  ? 249 SER   A N   1 
ATOM   1877 C  CA  . SER   A 1 249 ? -24.77179 -44.16896 -31.94309 1.000 83.57164  ? 249 SER   A CA  1 
ATOM   1878 C  C   . SER   A 1 249 ? -23.36734 -43.63124 -32.24789 1.000 99.37559  ? 249 SER   A C   1 
ATOM   1879 O  O   . SER   A 1 249 ? -23.02453 -43.26003 -33.37397 1.000 94.26383  ? 249 SER   A O   1 
ATOM   1880 C  CB  . SER   A 1 249 ? -25.52280 -44.55281 -33.21123 1.000 71.30205  ? 249 SER   A CB  1 
ATOM   1881 N  N   . HIS   A 1 250 ? -22.53673 -43.60536 -31.20484 1.000 94.36954  ? 250 HIS   A N   1 
ATOM   1882 C  CA  . HIS   A 1 250 ? -21.12846 -43.26398 -31.36719 1.000 93.22813  ? 250 HIS   A CA  1 
ATOM   1883 C  C   . HIS   A 1 250 ? -20.41189 -44.34730 -32.17301 1.000 87.88411  ? 250 HIS   A C   1 
ATOM   1884 O  O   . HIS   A 1 250 ? -20.89740 -45.47197 -32.31502 1.000 90.64594  ? 250 HIS   A O   1 
ATOM   1885 C  CB  . HIS   A 1 250 ? -20.45624 -43.09541 -30.00564 1.000 89.79586  ? 250 HIS   A CB  1 
ATOM   1886 C  CG  . HIS   A 1 250 ? -20.71041 -41.76683 -29.36461 1.000 88.75024  ? 250 HIS   A CG  1 
ATOM   1887 N  ND1 . HIS   A 1 250 ? -21.02441 -41.63443 -28.02774 1.000 85.43582  ? 250 HIS   A ND1 1 
ATOM   1888 C  CD2 . HIS   A 1 250 ? -20.68250 -40.51116 -29.87063 1.000 93.99382  ? 250 HIS   A CD2 1 
ATOM   1889 C  CE1 . HIS   A 1 250 ? -21.18398 -40.35561 -27.73867 1.000 83.48183  ? 250 HIS   A CE1 1 
ATOM   1890 N  NE2 . HIS   A 1 250 ? -20.98227 -39.65262 -28.83953 1.000 104.66315 ? 250 HIS   A NE2 1 
ATOM   1891 N  N   . HIS   A 1 251 ? -19.23549 -44.00258 -32.69921 1.000 92.85220  ? 251 HIS   A N   1 
ATOM   1892 C  CA  . HIS   A 1 251 ? -18.50673 -44.88608 -33.60326 1.000 109.27753 ? 251 HIS   A CA  1 
ATOM   1893 C  C   . HIS   A 1 251 ? -17.06152 -45.06646 -33.14846 1.000 106.01017 ? 251 HIS   A C   1 
ATOM   1894 O  O   . HIS   A 1 251 ? -16.40306 -44.10619 -32.73636 1.000 102.25696 ? 251 HIS   A O   1 
ATOM   1895 C  CB  . HIS   A 1 251 ? -18.54663 -44.34687 -35.03974 1.000 106.04584 ? 251 HIS   A CB  1 
ATOM   1896 C  CG  . HIS   A 1 251 ? -19.81901 -44.66082 -35.76552 1.000 111.57338 ? 251 HIS   A CG  1 
ATOM   1897 N  ND1 . HIS   A 1 251 ? -20.83532 -43.74097 -35.91829 1.000 104.39239 ? 251 HIS   A ND1 1 
ATOM   1898 C  CD2 . HIS   A 1 251 ? -20.23942 -45.79199 -36.38134 1.000 105.59763 ? 251 HIS   A CD2 1 
ATOM   1899 C  CE1 . HIS   A 1 251 ? -21.82661 -44.29216 -36.59636 1.000 99.82842  ? 251 HIS   A CE1 1 
ATOM   1900 N  NE2 . HIS   A 1 251 ? -21.48985 -45.53544 -36.89060 1.000 98.82468  ? 251 HIS   A NE2 1 
ATOM   1901 N  N   . HIS   A 1 252 ? -16.57473 -46.30490 -33.23133 1.000 104.88637 ? 252 HIS   A N   1 
ATOM   1902 C  CA  . HIS   A 1 252 ? -15.20349 -46.63623 -32.84201 1.000 111.87384 ? 252 HIS   A CA  1 
ATOM   1903 C  C   . HIS   A 1 252 ? -14.19394 -45.94137 -33.74800 1.000 113.04035 ? 252 HIS   A C   1 
ATOM   1904 O  O   . HIS   A 1 252 ? -14.10676 -46.24561 -34.93797 1.000 111.38743 ? 252 HIS   A O   1 
ATOM   1905 C  CB  . HIS   A 1 252 ? -14.97115 -48.15244 -32.88240 1.000 107.74937 ? 252 HIS   A CB  1 
ATOM   1906 C  CG  . HIS   A 1 252 ? -15.35221 -48.86111 -31.61808 1.000 115.39968 ? 252 HIS   A CG  1 
ATOM   1907 N  ND1 . HIS   A 1 252 ? -16.01049 -50.07310 -31.61307 1.000 116.81144 ? 252 HIS   A ND1 1 
ATOM   1908 C  CD2 . HIS   A 1 252 ? -15.17455 -48.52508 -30.31808 1.000 113.02601 ? 252 HIS   A CD2 1 
ATOM   1909 C  CE1 . HIS   A 1 252 ? -16.21763 -50.45479 -30.36517 1.000 113.13201 ? 252 HIS   A CE1 1 
ATOM   1910 N  NE2 . HIS   A 1 252 ? -15.72133 -49.53248 -29.55997 1.000 113.29898 ? 252 HIS   A NE2 1 
HETATM 1911 C  C13 . A1AVZ B 2 .   ? -36.41930 -10.81033 1.85793   1.000 55.88326  ? 301 A1AVZ A C13 1 
HETATM 1912 C  C15 . A1AVZ B 2 .   ? -34.39204 -11.61812 2.88287   1.000 55.40255  ? 301 A1AVZ A C15 1 
HETATM 1913 C  C17 . A1AVZ B 2 .   ? -34.35595 -9.60943  1.50284   1.000 53.61646  ? 301 A1AVZ A C17 1 
HETATM 1914 C  C20 . A1AVZ B 2 .   ? -32.00121 -9.05560  1.49300   1.000 61.46630  ? 301 A1AVZ A C20 1 
HETATM 1915 C  C22 . A1AVZ B 2 .   ? -31.25907 -10.82288 3.20755   1.000 57.55567  ? 301 A1AVZ A C22 1 
HETATM 1916 C  C24 . A1AVZ B 2 .   ? -29.81594 -10.31942 3.19114   1.000 45.89220  ? 301 A1AVZ A C24 1 
HETATM 1917 C  C26 . A1AVZ B 2 .   ? -39.68978 -5.72112  7.55913   1.000 51.63802  ? 301 A1AVZ A C26 1 
HETATM 1918 C  C28 . A1AVZ B 2 .   ? -39.67316 -4.19674  7.52889   1.000 54.13978  ? 301 A1AVZ A C28 1 
HETATM 1919 C  C01 . A1AVZ B 2 .   ? -39.87437 -7.79387  8.73815   1.000 51.30186  ? 301 A1AVZ A C01 1 
HETATM 1920 C  C03 . A1AVZ B 2 .   ? -39.59218 -7.82076  6.45264   1.000 47.31048  ? 301 A1AVZ A C03 1 
HETATM 1921 C  C05 . A1AVZ B 2 .   ? -39.55478 -7.95887  3.93161   1.000 42.47968  ? 301 A1AVZ A C05 1 
HETATM 1922 C  C06 . A1AVZ B 2 .   ? -38.66967 -8.67387  2.92106   1.000 40.45265  ? 301 A1AVZ A C06 1 
HETATM 1923 C  C08 . A1AVZ B 2 .   ? -38.84244 -10.72191 4.21217   1.000 38.18859  ? 301 A1AVZ A C08 1 
HETATM 1924 C  C09 . A1AVZ B 2 .   ? -39.74333 -9.99757  5.20608   1.000 41.41920  ? 301 A1AVZ A C09 1 
HETATM 1925 C  C14 . A1AVZ B 2 .   ? -35.75815 -11.75341 2.66757   1.000 48.68411  ? 301 A1AVZ A C14 1 
HETATM 1926 C  C16 . A1AVZ B 2 .   ? -33.68888 -10.55027 2.29796   1.000 49.95982  ? 301 A1AVZ A C16 1 
HETATM 1927 C  C18 . A1AVZ B 2 .   ? -35.73738 -9.73119  1.27962   1.000 43.88568  ? 301 A1AVZ A C18 1 
HETATM 1928 C  C19 . A1AVZ B 2 .   ? -33.33984 -8.57459  1.02361   1.000 55.15941  ? 301 A1AVZ A C19 1 
HETATM 1929 C  C25 . A1AVZ B 2 .   ? -39.55531 -6.43994  6.38723   1.000 36.82174  ? 301 A1AVZ A C25 1 
HETATM 1930 C  C27 . A1AVZ B 2 .   ? -39.85419 -6.40648  8.76071   1.000 50.15709  ? 301 A1AVZ A C27 1 
HETATM 1931 F  F29 . A1AVZ B 2 .   ? -38.38690 -3.78174  7.60939   1.000 52.40905  ? 301 A1AVZ A F29 1 
HETATM 1932 F  F30 . A1AVZ B 2 .   ? -40.20596 -3.71433  6.36339   1.000 54.21456  ? 301 A1AVZ A F30 1 
HETATM 1933 F  F31 . A1AVZ B 2 .   ? -40.38138 -3.74389  8.60404   1.000 55.25055  ? 301 A1AVZ A F31 1 
HETATM 1934 N  N02 . A1AVZ B 2 .   ? -39.74847 -8.45441  7.60303   1.000 43.16208  ? 301 A1AVZ A N02 1 
HETATM 1935 N  N04 . A1AVZ B 2 .   ? -39.44186 -8.58075  5.23758   1.000 41.98560  ? 301 A1AVZ A N04 1 
HETATM 1936 N  N07 . A1AVZ B 2 .   ? -38.89318 -10.12089 2.88960   1.000 48.06846  ? 301 A1AVZ A N07 1 
HETATM 1937 N  N21 . A1AVZ B 2 .   ? -32.24780 -10.17445 2.37153   1.000 61.11489  ? 301 A1AVZ A N21 1 
HETATM 1938 O  O11 . A1AVZ B 2 .   ? -38.60625 -10.46644 0.28444   1.000 45.46660  ? 301 A1AVZ A O11 1 
HETATM 1939 O  O12 . A1AVZ B 2 .   ? -38.62966 -12.38801 1.59929   1.000 51.63381  ? 301 A1AVZ A O12 1 
HETATM 1940 O  O23 . A1AVZ B 2 .   ? -31.57531 -11.74131 3.89036   1.000 54.51072  ? 301 A1AVZ A O23 1 
HETATM 1941 S  S10 . A1AVZ B 2 .   ? -38.20061 -10.98931 1.60061   1.000 41.53764  ? 301 A1AVZ A S10 1 
HETATM 1942 O  O1  . PG4   C 3 .   ? -27.38606 -43.47408 0.04256   1.000 60.48316  ? 302 PG4   A O1  1 
HETATM 1943 C  C1  . PG4   C 3 .   ? -28.27485 -43.55349 -1.06743  1.000 62.26470  ? 302 PG4   A C1  1 
HETATM 1944 C  C2  . PG4   C 3 .   ? -29.01428 -42.26590 -1.29432  1.000 76.44457  ? 302 PG4   A C2  1 
HETATM 1945 O  O2  . PG4   C 3 .   ? -30.28096 -42.32115 -0.64579  1.000 70.87190  ? 302 PG4   A O2  1 
HETATM 1946 C  C3  . PG4   C 3 .   ? -30.94322 -41.06376 -0.60284  1.000 73.19301  ? 302 PG4   A C3  1 
HETATM 1947 C  C4  . PG4   C 3 .   ? -32.20853 -41.16452 0.19094   1.000 66.25040  ? 302 PG4   A C4  1 
HETATM 1948 O  O3  . PG4   C 3 .   ? -32.03101 -42.09408 1.25914   1.000 75.15414  ? 302 PG4   A O3  1 
HETATM 1949 C  C5  . PG4   C 3 .   ? -32.99194 -41.82462 2.27361   1.000 55.46448  ? 302 PG4   A C5  1 
HETATM 1950 C  C6  . PG4   C 3 .   ? -33.35999 -43.08865 2.98552   1.000 65.90363  ? 302 PG4   A C6  1 
HETATM 1951 O  O4  . PG4   C 3 .   ? -32.20435 -43.75668 3.50032   1.000 79.96569  ? 302 PG4   A O4  1 
HETATM 1952 C  C7  . PG4   C 3 .   ? -32.42943 -45.15096 3.32594   1.000 67.76047  ? 302 PG4   A C7  1 
HETATM 1953 C  C8  . PG4   C 3 .   ? -31.63995 -45.95707 4.31230   1.000 64.66656  ? 302 PG4   A C8  1 
HETATM 1954 O  O5  . PG4   C 3 .   ? -30.25053 -45.78012 4.08849   1.000 76.60669  ? 302 PG4   A O5  1 
HETATM 1955 MN MN  . MN    D 4 .   ? -29.64667 -19.68392 0.59840   1.000 55.22247  ? 303 MN    A MN  1 
HETATM 1956 MN MN  . MN    E 4 .   ? -29.40635 -18.26121 3.54583   1.000 59.57217  ? 304 MN    A MN  1 
HETATM 1957 O  O   . HOH   F 5 .   ? -51.43520 -36.55532 3.74219   1.000 59.44082  ? 401 HOH   A O   1 
HETATM 1958 O  O   . HOH   F 5 .   ? -32.95783 -4.92589  1.05828   1.000 66.32834  ? 402 HOH   A O   1 
HETATM 1959 O  O   . HOH   F 5 .   ? -46.63970 -23.81439 -8.31878  1.000 56.68073  ? 403 HOH   A O   1 
HETATM 1960 O  O   . HOH   F 5 .   ? -32.35501 -19.49357 11.77585  1.000 43.63009  ? 404 HOH   A O   1 
HETATM 1961 O  O   . HOH   F 5 .   ? -26.78945 -18.48456 15.84582  1.000 58.20436  ? 405 HOH   A O   1 
HETATM 1962 O  O   . HOH   F 5 .   ? -30.12136 -20.72389 12.39496  1.000 45.35753  ? 406 HOH   A O   1 
HETATM 1963 O  O   . HOH   F 5 .   ? -48.56266 -18.27361 2.57034   1.000 44.81829  ? 407 HOH   A O   1 
HETATM 1964 O  O   . HOH   F 5 .   ? -35.66730 -21.19069 13.06556  1.000 43.16408  ? 408 HOH   A O   1 
HETATM 1965 O  O   . HOH   F 5 .   ? -44.24428 -22.37002 -11.56002 1.000 52.03256  ? 409 HOH   A O   1 
HETATM 1966 O  O   . HOH   F 5 .   ? -33.99301 -36.77553 14.70686  1.000 49.42256  ? 410 HOH   A O   1 
HETATM 1967 O  O   . HOH   F 5 .   ? -25.77242 -23.79506 1.49435   1.000 44.94578  ? 411 HOH   A O   1 
HETATM 1968 O  O   . HOH   F 5 .   ? -49.26728 -20.26964 4.52652   1.000 42.82863  ? 412 HOH   A O   1 
HETATM 1969 O  O   . HOH   F 5 .   ? -31.09877 -17.39041 11.03719  1.000 50.47510  ? 413 HOH   A O   1 
HETATM 1970 O  O   . HOH   F 5 .   ? -50.88510 -19.96658 0.33088   1.000 50.15644  ? 414 HOH   A O   1 
HETATM 1971 O  O   . HOH   F 5 .   ? -18.13006 -25.98864 -2.22315  1.000 48.36599  ? 415 HOH   A O   1 
HETATM 1972 O  O   . HOH   F 5 .   ? -45.03954 -35.97424 -1.22728  1.000 48.10840  ? 416 HOH   A O   1 
HETATM 1973 O  O   . HOH   F 5 .   ? -18.03559 -24.36075 2.72407   1.000 47.08220  ? 417 HOH   A O   1 
HETATM 1974 O  O   . HOH   F 5 .   ? -40.84240 -17.76314 -3.27945  1.000 43.55256  ? 418 HOH   A O   1 
HETATM 1975 O  O   . HOH   F 5 .   ? -24.39567 -24.44485 -3.93635  1.000 47.16196  ? 419 HOH   A O   1 
HETATM 1976 O  O   . HOH   F 5 .   ? -31.83471 -22.29781 -5.31346  1.000 56.88669  ? 420 HOH   A O   1 
HETATM 1977 O  O   . HOH   F 5 .   ? -45.42489 -15.17623 1.88517   1.000 44.20663  ? 421 HOH   A O   1 
HETATM 1978 O  O   . HOH   F 5 .   ? -31.21909 -31.46716 -12.39498 1.000 45.23240  ? 422 HOH   A O   1 
HETATM 1979 O  O   . HOH   F 5 .   ? -28.36107 -18.28156 1.65727   1.000 48.32868  ? 423 HOH   A O   1 
HETATM 1980 O  O   . HOH   F 5 .   ? -38.97247 -23.28500 -7.14533  1.000 48.26934  ? 424 HOH   A O   1 
HETATM 1981 O  O   . HOH   F 5 .   ? -43.14160 -33.50052 11.82020  1.000 41.43685  ? 425 HOH   A O   1 
HETATM 1982 O  O   . HOH   F 5 .   ? -39.28928 -14.15869 5.82043   1.000 43.23901  ? 426 HOH   A O   1 
HETATM 1983 O  O   . HOH   F 5 .   ? -36.02930 -13.04856 -5.67829  1.000 74.75212  ? 427 HOH   A O   1 
HETATM 1984 O  O   . HOH   F 5 .   ? -19.18948 -22.39906 4.19930   1.000 41.53042  ? 428 HOH   A O   1 
HETATM 1985 O  O   . HOH   F 5 .   ? -43.80674 -25.88748 15.57936  1.000 53.34511  ? 429 HOH   A O   1 
HETATM 1986 O  O   . HOH   F 5 .   ? -29.64408 -28.84993 0.22224   1.000 37.71145  ? 430 HOH   A O   1 
HETATM 1987 O  O   . HOH   F 5 .   ? -53.41474 -19.10299 3.36774   1.000 64.10847  ? 431 HOH   A O   1 
HETATM 1988 O  O   . HOH   F 5 .   ? -49.02619 -39.87898 2.44294   1.000 51.97297  ? 432 HOH   A O   1 
HETATM 1989 O  O   . HOH   F 5 .   ? -53.960   -6.736    0.031     1.000 62.76381  ? 433 HOH   A O   1 
HETATM 1990 O  O   . HOH   F 5 .   ? -43.08601 -17.54087 -5.66094  1.000 44.65491  ? 434 HOH   A O   1 
HETATM 1991 O  O   . HOH   F 5 .   ? -46.66132 -17.59825 13.86162  1.000 56.84281  ? 435 HOH   A O   1 
HETATM 1992 O  O   . HOH   F 5 .   ? -44.44733 -34.47210 -3.24822  1.000 51.29035  ? 436 HOH   A O   1 
HETATM 1993 O  O   . HOH   F 5 .   ? -23.16698 -16.34072 1.21842   1.000 66.48439  ? 437 HOH   A O   1 
HETATM 1994 O  O   . HOH   F 5 .   ? -35.57890 -32.99360 17.43352  1.000 51.96708  ? 438 HOH   A O   1 
HETATM 1995 O  O   . HOH   F 5 .   ? -36.46668 -35.10880 17.77214  1.000 59.79177  ? 439 HOH   A O   1 
HETATM 1996 O  O   . HOH   F 5 .   ? -28.50938 -6.22397  2.46106   1.000 63.64489  ? 440 HOH   A O   1 
HETATM 1997 O  O   . HOH   F 5 .   ? -24.71685 -16.60156 -0.47665  1.000 54.62096  ? 441 HOH   A O   1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
1    N N   . ALA A 2   ? 0.66394 0.56541 0.61833 0.06729  -0.03069 0.02667  2   ALA A N   
2    C CA  . ALA A 2   ? 0.62701 0.55847 0.59129 0.07428  -0.02027 0.02347  2   ALA A CA  
3    C C   . ALA A 2   ? 0.54778 0.49939 0.52057 0.05475  -0.01991 0.01977  2   ALA A C   
4    O O   . ALA A 2   ? 0.60968 0.54582 0.57441 0.04283  -0.02423 0.01451  2   ALA A O   
5    C CB  . ALA A 2   ? 0.64336 0.55296 0.58876 0.09313  -0.01501 0.01430  2   ALA A CB  
6    N N   . THR A 3   ? 0.48794 0.47318 0.47647 0.05150  -0.01629 0.02400  3   THR A N   
7    C CA  . THR A 3   ? 0.46746 0.46608 0.45912 0.03659  -0.01677 0.01976  3   THR A CA  
8    C C   . THR A 3   ? 0.60640 0.61755 0.60193 0.04071  -0.01075 0.01651  3   THR A C   
9    O O   . THR A 3   ? 0.48252 0.51154 0.48811 0.05143  -0.00631 0.02383  3   THR A O   
10   C CB  . THR A 3   ? 0.54457 0.56280 0.54401 0.02697  -0.02178 0.02680  3   THR A CB  
11   O OG1 . THR A 3   ? 0.58778 0.59712 0.58287 0.02433  -0.02623 0.03196  3   THR A OG1 
12   C CG2 . THR A 3   ? 0.47069 0.49341 0.46501 0.01532  -0.02322 0.02057  3   THR A CG2 
13   N N   . LEU A 4   ? 0.50786 0.51328 0.49699 0.03272  -0.01031 0.00813  4   LEU A N   
14   C CA  . LEU A 4   ? 0.51645 0.52992 0.50650 0.03574  -0.00508 0.00532  4   LEU A CA  
15   C C   . LEU A 4   ? 0.54283 0.57160 0.53973 0.02296  -0.00857 0.00674  4   LEU A C   
16   O O   . LEU A 4   ? 0.46613 0.48895 0.45748 0.01363  -0.01352 0.00324  4   LEU A O   
17   C CB  . LEU A 4   ? 0.55212 0.54274 0.52632 0.03759  -0.00382 -0.00508 4   LEU A CB  
18   C CG  . LEU A 4   ? 0.55460 0.51640 0.51211 0.04938  -0.00463 -0.00918 4   LEU A CG  
19   C CD1 . LEU A 4   ? 0.54022 0.47954 0.48050 0.04712  -0.00732 -0.01888 4   LEU A CD1 
20   C CD2 . LEU A 4   ? 0.54469 0.51156 0.50045 0.07052  0.00296  -0.00474 4   LEU A CD2 
21   N N   . PHE A 5   ? 0.49796 0.54567 0.50513 0.02369  -0.00644 0.01337  5   PHE A N   
22   C CA  . PHE A 5   ? 0.37048 0.42602 0.38144 0.01045  -0.01298 0.01587  5   PHE A CA  
23   C C   . PHE A 5   ? 0.51241 0.57320 0.52425 0.01205  -0.00771 0.01618  5   PHE A C   
24   O O   . PHE A 5   ? 0.45892 0.53560 0.47804 0.02311  0.00062  0.02336  5   PHE A O   
25   C CB  . PHE A 5   ? 0.44035 0.51722 0.46678 0.00356  -0.02090 0.03004  5   PHE A CB  
26   C CG  . PHE A 5   ? 0.56474 0.63602 0.58737 0.00124  -0.02754 0.03029  5   PHE A CG  
27   C CD1 . PHE A 5   ? 0.45205 0.52903 0.48094 0.01244  -0.02305 0.03520  5   PHE A CD1 
28   C CD2 . PHE A 5   ? 0.48124 0.53867 0.48990 -0.01001 -0.03838 0.02563  5   PHE A CD2 
29   C CE1 . PHE A 5   ? 0.47867 0.55124 0.50382 0.00990  -0.02941 0.03718  5   PHE A CE1 
30   C CE2 . PHE A 5   ? 0.49192 0.54531 0.49367 -0.01090 -0.04383 0.02668  5   PHE A CE2 
31   C CZ  . PHE A 5   ? 0.46568 0.52831 0.47754 -0.00211 -0.03927 0.03321  5   PHE A CZ  
32   N N   . ILE A 6   ? 0.49177 0.53968 0.49432 0.00341  -0.01182 0.00927  6   ILE A N   
33   C CA  . ILE A 6   ? 0.49349 0.54516 0.49607 0.00234  -0.00899 0.01090  6   ILE A CA  
34   C C   . ILE A 6   ? 0.43701 0.48099 0.43679 -0.01205 -0.02048 0.01243  6   ILE A C   
35   O O   . ILE A 6   ? 0.42364 0.45232 0.41359 -0.01757 -0.02909 0.00714  6   ILE A O   
36   C CB  . ILE A 6   ? 0.53792 0.57303 0.52592 0.00961  -0.00282 -0.00093 6   ILE A CB  
37   C CG1 . ILE A 6   ? 0.44227 0.45856 0.41948 0.00470  -0.00789 -0.01119 6   ILE A CG1 
38   C CG2 . ILE A 6   ? 0.44138 0.47331 0.42406 0.02397  0.00498  -0.00351 6   ILE A CG2 
39   C CD1 . ILE A 6   ? 0.36523 0.36944 0.33224 0.00860  -0.00500 -0.01942 6   ILE A CD1 
40   N N   . ALA A 7   ? 0.37024 0.42222 0.37520 -0.01698 -0.02117 0.02025  7   ALA A N   
41   C CA  . ALA A 7   ? 0.49646 0.53315 0.49486 -0.03088 -0.03459 0.02205  7   ALA A CA  
42   C C   . ALA A 7   ? 0.51690 0.56159 0.51984 -0.03359 -0.03200 0.03015  7   ALA A C   
43   O O   . ALA A 7   ? 0.49053 0.55930 0.50385 -0.02514 -0.01988 0.03761  7   ALA A O   
44   C CB  . ALA A 7   ? 0.42693 0.46862 0.43355 -0.04524 -0.04974 0.03418  7   ALA A CB  
45   N N   . ASP A 8   ? 0.57464 0.59605 0.56575 -0.04338 -0.04354 0.02851  8   ASP A N   
46   C CA  . ASP A 8   ? 0.44636 0.47371 0.44329 -0.05212 -0.04694 0.04152  8   ASP A CA  
47   C C   . ASP A 8   ? 0.48267 0.51994 0.47758 -0.03931 -0.03140 0.03812  8   ASP A C   
48   O O   . ASP A 8   ? 0.50128 0.56471 0.50835 -0.03925 -0.02470 0.05307  8   ASP A O   
49   C CB  . ASP A 8   ? 0.43472 0.49502 0.45713 -0.06490 -0.05204 0.06627  8   ASP A CB  
50   C CG  . ASP A 8   ? 0.54981 0.59375 0.57075 -0.08344 -0.07441 0.07204  8   ASP A CG  
51   O OD1 . ASP A 8   ? 0.62991 0.63898 0.63364 -0.09565 -0.09166 0.07004  8   ASP A OD1 
52   O OD2 . ASP A 8   ? 0.55819 0.62017 0.59183 -0.08517 -0.07646 0.07814  8   ASP A OD2 
53   N N   . LEU A 9   ? 0.52288 0.54116 0.50176 -0.02835 -0.02624 0.02008  9   LEU A N   
54   C CA  . LEU A 9   ? 0.42991 0.45017 0.40167 -0.01819 -0.01610 0.01505  9   LEU A CA  
55   C C   . LEU A 9   ? 0.59595 0.60325 0.56007 -0.02372 -0.02210 0.01812  9   LEU A C   
56   O O   . LEU A 9   ? 0.53837 0.55575 0.50073 -0.01972 -0.01546 0.02288  9   LEU A O   
57   C CB  . LEU A 9   ? 0.47350 0.48048 0.43450 -0.00850 -0.01229 -0.00146 9   LEU A CB  
58   C CG  . LEU A 9   ? 0.61301 0.62910 0.57721 -0.00029 -0.00488 -0.00472 9   LEU A CG  
59   C CD1 . LEU A 9   ? 0.39105 0.40817 0.36270 -0.00477 -0.00973 -0.00356 9   LEU A CD1 
60   C CD2 . LEU A 9   ? 0.46486 0.46809 0.41735 0.00662  -0.00267 -0.01672 9   LEU A CD2 
61   N N   . HIS A 10  ? 0.44536 0.42678 0.40058 -0.03084 -0.03500 0.01490  10  HIS A N   
62   C CA  . HIS A 10  ? 0.48652 0.44825 0.43139 -0.03490 -0.04303 0.01761  10  HIS A CA  
63   C C   . HIS A 10  ? 0.45307 0.41459 0.39011 -0.02348 -0.03483 0.00999  10  HIS A C   
64   O O   . HIS A 10  ? 0.52012 0.48457 0.45580 -0.02531 -0.03455 0.01798  10  HIS A O   
65   C CB  . HIS A 10  ? 0.49907 0.47379 0.45574 -0.04923 -0.04863 0.03861  10  HIS A CB  
66   C CG  . HIS A 10  ? 0.64456 0.62757 0.61430 -0.06322 -0.05824 0.05065  10  HIS A CG  
67   N ND1 . HIS A 10  ? 0.62490 0.64869 0.61756 -0.06503 -0.04970 0.06574  10  HIS A ND1 
68   C CD2 . HIS A 10  ? 0.62699 0.58223 0.58827 -0.07528 -0.07691 0.05056  10  HIS A CD2 
69   C CE1 . HIS A 10  ? 0.63953 0.66530 0.64252 -0.07981 -0.06317 0.07643  10  HIS A CE1 
70   N NE2 . HIS A 10  ? 0.60614 0.58778 0.58837 -0.08736 -0.08102 0.06657  10  HIS A NE2 
71   N N   . LEU A 11  ? 0.50555 0.46522 0.43816 -0.01310 -0.02952 -0.00333 11  LEU A N   
72   C CA  . LEU A 11  ? 0.54876 0.50953 0.47571 -0.00473 -0.02514 -0.00895 11  LEU A CA  
73   C C   . LEU A 11  ? 0.54304 0.48583 0.46041 -0.00366 -0.03242 -0.00719 11  LEU A C   
74   O O   . LEU A 11  ? 0.51558 0.43655 0.42459 -0.00366 -0.04061 -0.00879 11  LEU A O   
75   C CB  . LEU A 11  ? 0.47713 0.43983 0.40430 0.00253  -0.02199 -0.01917 11  LEU A CB  
76   C CG  . LEU A 11  ? 0.57415 0.54890 0.50800 0.00253  -0.01628 -0.02149 11  LEU A CG  
77   C CD1 . LEU A 11  ? 0.59435 0.56966 0.52963 0.00648  -0.01593 -0.02782 11  LEU A CD1 
78   C CD2 . LEU A 11  ? 0.46383 0.44696 0.39476 0.00493  -0.01094 -0.02029 11  LEU A CD2 
79   N N   . GLN A 12  ? 0.51977 0.46816 0.43447 -0.00139 -0.03042 -0.00409 12  GLN A N   
80   C CA  . GLN A 12  ? 0.61584 0.54925 0.52206 0.00067  -0.03697 -0.00041 12  GLN A CA  
81   C C   . GLN A 12  ? 0.64552 0.59189 0.54965 0.00454  -0.03324 0.00064  12  GLN A C   
82   O O   . GLN A 12  ? 0.61007 0.57140 0.51435 0.00305  -0.02704 0.00183  12  GLN A O   
83   C CB  . GLN A 12  ? 0.55754 0.47883 0.46177 -0.01031 -0.04477 0.01205  12  GLN A CB  
84   C CG  . GLN A 12  ? 0.61141 0.55756 0.52452 -0.01813 -0.03838 0.02447  12  GLN A CG  
85   C CD  . GLN A 12  ? 0.75361 0.69583 0.67111 -0.03275 -0.04697 0.04241  12  GLN A CD  
86   O OE1 . GLN A 12  ? 0.70524 0.65743 0.63420 -0.04259 -0.04876 0.05052  12  GLN A OE1 
87   N NE2 . GLN A 12  ? 0.78979 0.71962 0.69988 -0.03565 -0.05353 0.05135  12  GLN A NE2 
88   N N   . THR A 13  ? 0.55708 0.49605 0.45632 0.01126  -0.03777 0.00038  13  THR A N   
89   C CA  . THR A 13  ? 0.58982 0.54057 0.48642 0.01400  -0.03742 0.00137  13  THR A CA  
90   C C   . THR A 13  ? 0.61082 0.56525 0.49929 0.00894  -0.03629 0.01015  13  THR A C   
91   O O   . THR A 13  ? 0.58999 0.55323 0.47046 0.01045  -0.03505 0.00909  13  THR A O   
92   C CB  . THR A 13  ? 0.61920 0.56584 0.51540 0.02308  -0.04301 0.00278  13  THR A CB  
93   O OG1 . THR A 13  ? 0.64800 0.57196 0.53686 0.02545  -0.04831 0.00757  13  THR A OG1 
94   C CG2 . THR A 13  ? 0.64221 0.59776 0.54775 0.03087  -0.04108 -0.00311 13  THR A CG2 
95   N N   . GLU A 14  ? 0.56619 0.51356 0.45462 0.00254  -0.03790 0.02016  14  GLU A N   
96   C CA  . GLU A 14  ? 0.70077 0.65872 0.58409 -0.00233 -0.03478 0.03298  14  GLU A CA  
97   C C   . GLU A 14  ? 0.63724 0.61599 0.52078 -0.00154 -0.02360 0.03319  14  GLU A C   
98   O O   . GLU A 14  ? 0.66440 0.65711 0.53980 -0.00029 -0.01767 0.04316  14  GLU A O   
99   C CB  . GLU A 14  ? 0.74784 0.69422 0.63496 -0.01264 -0.04189 0.04766  14  GLU A CB  
100  C CG  . GLU A 14  ? 0.84913 0.76915 0.72859 -0.01031 -0.05342 0.04948  14  GLU A CG  
101  C CD  . GLU A 14  ? 0.98903 0.88035 0.86727 -0.00971 -0.06234 0.04287  14  GLU A CD  
102  O OE1 . GLU A 14  ? 0.97185 0.86737 0.85627 -0.01053 -0.05886 0.03456  14  GLU A OE1 
103  O OE2 . GLU A 14  ? 1.21752 1.07924 1.08504 -0.00691 -0.07331 0.04586  14  GLU A OE2 
104  N N   . GLU A 15  ? 0.63624 0.61764 0.52685 0.00009  -0.01989 0.02347  15  GLU A N   
105  C CA  . GLU A 15  ? 0.62023 0.61809 0.50923 0.00474  -0.00928 0.02280  15  GLU A CA  
106  C C   . GLU A 15  ? 0.65069 0.64134 0.53090 0.01209  -0.00880 0.00646  15  GLU A C   
107  O O   . GLU A 15  ? 0.54358 0.53430 0.43177 0.01254  -0.00685 0.00001  15  GLU A O   
108  C CB  . GLU A 15  ? 0.63194 0.63990 0.53859 -0.00162 -0.00701 0.02994  15  GLU A CB  
109  C CG  . GLU A 15  ? 0.66802 0.68269 0.58523 -0.01364 -0.01140 0.04978  15  GLU A CG  
110  C CD  . GLU A 15  ? 0.84121 0.88161 0.75485 -0.01068 -0.00181 0.06658  15  GLU A CD  
111  O OE1 . GLU A 15  ? 1.06336 1.11045 0.98486 -0.02206 -0.00660 0.08619  15  GLU A OE1 
112  O OE2 . GLU A 15  ? 0.81485 0.86714 0.71533 0.00366  0.00994  0.06110  15  GLU A OE2 
113  N N   . PRO A 16  ? 0.71970 0.70292 0.58283 0.01626  -0.01266 0.00106  16  PRO A N   
114  C CA  . PRO A 16  ? 0.65844 0.63132 0.51359 0.01879  -0.01710 -0.01195 16  PRO A CA  
115  C C   . PRO A 16  ? 0.66125 0.63178 0.50517 0.02626  -0.01002 -0.01793 16  PRO A C   
116  O O   . PRO A 16  ? 0.74621 0.70677 0.59111 0.02519  -0.01435 -0.02684 16  PRO A O   
117  C CB  . PRO A 16  ? 0.61628 0.58133 0.45257 0.01960  -0.02552 -0.01305 16  PRO A CB  
118  C CG  . PRO A 16  ? 0.63288 0.60543 0.45943 0.02250  -0.02009 -0.00214 16  PRO A CG  
119  C CD  . PRO A 16  ? 0.59634 0.57927 0.44584 0.01711  -0.01548 0.00815  16  PRO A CD  
120  N N   . ALA A 17  ? 0.60449 0.58560 0.43891 0.03489  0.00108  -0.01134 17  ALA A N   
121  C CA  . ALA A 17  ? 0.62736 0.60557 0.44819 0.04738  0.00908  -0.01671 17  ALA A CA  
122  C C   . ALA A 17  ? 0.77221 0.75655 0.61701 0.04365  0.01117  -0.01749 17  ALA A C   
123  O O   . ALA A 17  ? 0.67133 0.64260 0.50692 0.05028  0.01118  -0.02651 17  ALA A O   
124  C CB  . ALA A 17  ? 0.67483 0.67204 0.48319 0.06111  0.02351  -0.00546 17  ALA A CB  
125  N N   . ILE A 18  ? 0.65477 0.65483 0.52688 0.03309  0.01120  -0.00800 18  ILE A N   
126  C CA  . ILE A 18  ? 0.68984 0.69353 0.58143 0.02876  0.01098  -0.00909 18  ILE A CA  
127  C C   . ILE A 18  ? 0.67548 0.66106 0.56736 0.02417  0.00195  -0.02139 18  ILE A C   
128  O O   . ILE A 18  ? 0.55953 0.54046 0.45377 0.02614  0.00223  -0.02661 18  ILE A O   
129  C CB  . ILE A 18  ? 0.66297 0.68016 0.57704 0.01720  0.00888  0.00327  18  ILE A CB  
130  C CG1 . ILE A 18  ? 0.67686 0.71994 0.59713 0.01899  0.01728  0.02108  18  ILE A CG1 
131  C CG2 . ILE A 18  ? 0.72107 0.73777 0.65037 0.01216  0.00592  0.00075  18  ILE A CG2 
132  C CD1 . ILE A 18  ? 0.61991 0.66920 0.55606 0.00337  0.00978  0.03609  18  ILE A CD1 
133  N N   . THR A 19  ? 0.61668 0.59500 0.50766 0.01846  -0.00605 -0.02362 19  THR A N   
134  C CA  . THR A 19  ? 0.65521 0.62539 0.55039 0.01420  -0.01390 -0.03032 19  THR A CA  
135  C C   . THR A 19  ? 0.63382 0.58918 0.51264 0.01681  -0.01799 -0.03773 19  THR A C   
136  O O   . THR A 19  ? 0.55880 0.50946 0.44351 0.01390  -0.02111 -0.04078 19  THR A O   
137  C CB  . THR A 19  ? 0.54413 0.51500 0.44177 0.01069  -0.02083 -0.02806 19  THR A CB  
138  O OG1 . THR A 19  ? 0.60855 0.58359 0.51629 0.00962  -0.01930 -0.02257 19  THR A OG1 
139  C CG2 . THR A 19  ? 0.47329 0.44535 0.37925 0.00684  -0.02798 -0.03011 19  THR A CG2 
140  N N   . ALA A 20  ? 0.58438 0.52843 0.43879 0.02236  -0.01951 -0.04035 20  ALA A N   
141  C CA  . ALA A 20  ? 0.71545 0.63423 0.54449 0.02614  -0.02646 -0.04900 20  ALA A CA  
142  C C   . ALA A 20  ? 0.72718 0.64038 0.55295 0.03544  -0.01878 -0.05204 20  ALA A C   
143  O O   . ALA A 20  ? 0.80753 0.69922 0.62414 0.03406  -0.02688 -0.05800 20  ALA A O   
144  C CB  . ALA A 20  ? 0.63551 0.53966 0.43086 0.03431  -0.02848 -0.05213 20  ALA A CB  
145  N N   . GLY A 21  ? 0.67584 0.60925 0.51068 0.04404  -0.00457 -0.04569 21  GLY A N   
146  C CA  . GLY A 21  ? 0.56217 0.49658 0.39807 0.05433  0.00332  -0.04576 21  GLY A CA  
147  C C   . GLY A 21  ? 0.60280 0.54048 0.46270 0.04396  -0.00085 -0.04540 21  GLY A C   
148  O O   . GLY A 21  ? 0.53908 0.46287 0.39313 0.04902  -0.00206 -0.04923 21  GLY A O   
149  N N   . PHE A 22  ? 0.57146 0.52500 0.45508 0.03117  -0.00327 -0.04066 22  PHE A N   
150  C CA  . PHE A 22  ? 0.57412 0.53136 0.47607 0.02332  -0.00649 -0.04004 22  PHE A CA  
151  C C   . PHE A 22  ? 0.67475 0.61452 0.57070 0.01711  -0.01726 -0.04466 22  PHE A C   
152  O O   . PHE A 22  ? 0.55869 0.49346 0.45951 0.01522  -0.01947 -0.04458 22  PHE A O   
153  C CB  . PHE A 22  ? 0.51737 0.48977 0.43709 0.01534  -0.00687 -0.03519 22  PHE A CB  
154  C CG  . PHE A 22  ? 0.49467 0.47165 0.42803 0.01051  -0.00863 -0.03436 22  PHE A CG  
155  C CD1 . PHE A 22  ? 0.52940 0.50814 0.46744 0.01253  -0.00603 -0.03324 22  PHE A CD1 
156  C CD2 . PHE A 22  ? 0.51320 0.49407 0.45284 0.00648  -0.01211 -0.03369 22  PHE A CD2 
157  C CE1 . PHE A 22  ? 0.52184 0.50483 0.46919 0.00857  -0.00777 -0.03188 22  PHE A CE1 
158  C CE2 . PHE A 22  ? 0.46986 0.45575 0.41709 0.00531  -0.01212 -0.03248 22  PHE A CE2 
159  C CZ  . PHE A 22  ? 0.55035 0.53660 0.50071 0.00532  -0.01040 -0.03180 22  PHE A CZ  
160  N N   . LEU A 23  ? 0.61634 0.54777 0.50263 0.01236  -0.02564 -0.04639 23  LEU A N   
161  C CA  . LEU A 23  ? 0.63083 0.54868 0.51432 0.00230  -0.03949 -0.04657 23  LEU A CA  
162  C C   . LEU A 23  ? 0.72332 0.60885 0.58297 0.00647  -0.04582 -0.05286 23  LEU A C   
163  O O   . LEU A 23  ? 0.66525 0.54105 0.52957 -0.00173 -0.05444 -0.05041 23  LEU A O   
164  C CB  . LEU A 23  ? 0.56245 0.47873 0.43933 -0.00388 -0.04924 -0.04543 23  LEU A CB  
165  C CG  . LEU A 23  ? 0.70628 0.65089 0.60607 -0.00742 -0.04627 -0.03793 23  LEU A CG  
166  C CD1 . LEU A 23  ? 0.70201 0.64544 0.59383 -0.01152 -0.05610 -0.03582 23  LEU A CD1 
167  C CD2 . LEU A 23  ? 0.57578 0.53962 0.50000 -0.01361 -0.04672 -0.03024 23  LEU A CD2 
168  N N   . ARG A 24  ? 0.73586 0.60321 0.56736 0.02084  -0.04162 -0.06001 24  ARG A N   
169  C CA  . ARG A 24  ? 0.74612 0.57733 0.54764 0.03180  -0.04568 -0.06763 24  ARG A CA  
170  C C   . ARG A 24  ? 0.79591 0.63444 0.61286 0.03697  -0.03778 -0.06459 24  ARG A C   
171  O O   . ARG A 24  ? 0.71847 0.52837 0.52334 0.03635  -0.04727 -0.06707 24  ARG A O   
172  C CB  . ARG A 24  ? 0.72384 0.54229 0.49185 0.05253  -0.03738 -0.07425 24  ARG A CB  
173  C CG  . ARG A 24  ? 0.87027 0.64317 0.59602 0.06982  -0.04205 -0.08436 24  ARG A CG  
174  C CD  . ARG A 24  ? 0.88637 0.67206 0.60005 0.09816  -0.02091 -0.08397 24  ARG A CD  
175  N N   . PHE A 25  ? 0.76480 0.63906 0.60726 0.04083  -0.02274 -0.05815 25  PHE A N   
176  C CA  . PHE A 25  ? 0.60060 0.48576 0.46021 0.04355  -0.01699 -0.05353 25  PHE A CA  
177  C C   . PHE A 25  ? 0.74111 0.62306 0.61555 0.02719  -0.02763 -0.05012 25  PHE A C   
178  O O   . PHE A 25  ? 0.69226 0.55786 0.56289 0.02878  -0.03176 -0.04955 25  PHE A O   
179  C CB  . PHE A 25  ? 0.56128 0.48464 0.44604 0.04461  -0.00431 -0.04551 25  PHE A CB  
180  C CG  . PHE A 25  ? 0.63103 0.56964 0.53688 0.04217  -0.00167 -0.03930 25  PHE A CG  
181  C CD1 . PHE A 25  ? 0.65987 0.60211 0.56499 0.05643  0.00536  -0.03581 25  PHE A CD1 
182  C CD2 . PHE A 25  ? 0.46542 0.41629 0.39004 0.02799  -0.00574 -0.03601 25  PHE A CD2 
183  C CE1 . PHE A 25  ? 0.54673 0.50385 0.47116 0.05339  0.00607  -0.02892 25  PHE A CE1 
184  C CE2 . PHE A 25  ? 0.64800 0.61073 0.58718 0.02608  -0.00445 -0.03063 25  PHE A CE2 
185  C CZ  . PHE A 25  ? 0.61926 0.58497 0.55930 0.03723  0.00042  -0.02692 25  PHE A CZ  
186  N N   . LEU A 26  ? 0.60635 0.50535 0.49741 0.01288  -0.03167 -0.04601 26  LEU A N   
187  C CA  . LEU A 26  ? 0.67307 0.57963 0.58132 -0.00085 -0.03875 -0.03874 26  LEU A CA  
188  C C   . LEU A 26  ? 0.78044 0.65610 0.67462 -0.00961 -0.05518 -0.03809 26  LEU A C   
189  O O   . LEU A 26  ? 0.82381 0.69691 0.72644 -0.01678 -0.06029 -0.03126 26  LEU A O   
190  C CB  . LEU A 26  ? 0.56005 0.49302 0.48600 -0.00935 -0.03835 -0.03321 26  LEU A CB  
191  C CG  . LEU A 26  ? 0.56943 0.52666 0.50799 -0.00379 -0.02648 -0.03248 26  LEU A CG  
192  C CD1 . LEU A 26  ? 0.45874 0.43530 0.40896 -0.00800 -0.02705 -0.02748 26  LEU A CD1 
193  C CD2 . LEU A 26  ? 0.45121 0.41594 0.39829 -0.00158 -0.02128 -0.02978 26  LEU A CD2 
194  N N   . GLN A 27  ? 0.75130 0.60107 0.62218 -0.01070 -0.06578 -0.04400 27  GLN A N   
195  C CA  . GLN A 27  ? 0.72986 0.54164 0.58173 -0.02197 -0.08694 -0.04349 27  GLN A CA  
196  C C   . GLN A 27  ? 0.91083 0.67716 0.73031 -0.00816 -0.09044 -0.05262 27  GLN A C   
197  O O   . GLN A 27  ? 0.94546 0.66871 0.74223 -0.01683 -0.11094 -0.05340 27  GLN A O   
198  C CB  . GLN A 27  ? 0.74349 0.54132 0.57849 -0.02935 -0.10038 -0.04639 27  GLN A CB  
199  N N   . GLY A 28  ? 0.74646 0.52061 0.56295 0.01311  -0.07244 -0.05787 28  GLY A N   
200  C CA  . GLY A 28  ? 0.85323 0.58877 0.63946 0.03201  -0.07277 -0.06528 28  GLY A CA  
201  C C   . GLY A 28  ? 0.89026 0.64527 0.69678 0.04057  -0.06067 -0.05921 28  GLY A C   
202  O O   . GLY A 28  ? 1.18616 0.92032 0.99172 0.03506  -0.07055 -0.05501 28  GLY A O   
203  N N   . GLU A 29  ? 0.79164 0.58640 0.61691 0.05234  -0.04127 -0.05683 29  GLU A N   
204  C CA  . GLU A 29  ? 0.85945 0.67407 0.70314 0.06066  -0.03140 -0.04997 29  GLU A CA  
205  C C   . GLU A 29  ? 0.65440 0.49139 0.52834 0.04033  -0.03548 -0.04016 29  GLU A C   
206  O O   . GLU A 29  ? 0.76231 0.59038 0.63960 0.03976  -0.03946 -0.03496 29  GLU A O   
207  C CB  . GLU A 29  ? 0.77623 0.62975 0.63380 0.07462  -0.01304 -0.04661 29  GLU A CB  
208  N N   . ALA A 30  ? 0.69318 0.55885 0.58683 0.02589  -0.03397 -0.03696 30  ALA A N   
209  C CA  . ALA A 30  ? 0.67827 0.57067 0.59720 0.01295  -0.03341 -0.02770 30  ALA A CA  
210  C C   . ALA A 30  ? 0.71527 0.59199 0.63496 -0.00063 -0.04643 -0.02039 30  ALA A C   
211  O O   . ALA A 30  ? 0.63633 0.52858 0.57067 -0.00550 -0.04509 -0.01148 30  ALA A O   
212  C CB  . ALA A 30  ? 0.65088 0.57089 0.58359 0.00512  -0.02929 -0.02680 30  ALA A CB  
213  N N   . ARG A 31  ? 0.64499 0.49087 0.54821 -0.00826 -0.06072 -0.02228 31  ARG A N   
214  C CA  . ARG A 31  ? 0.72870 0.55958 0.63460 -0.02545 -0.07661 -0.01134 31  ARG A CA  
215  C C   . ARG A 31  ? 0.72466 0.53276 0.62339 -0.01986 -0.07985 -0.00810 31  ARG A C   
216  O O   . ARG A 31  ? 0.72568 0.53264 0.63425 -0.03482 -0.08973 0.00535  31  ARG A O   
217  C CB  . ARG A 31  ? 0.81084 0.60437 0.69543 -0.03613 -0.09622 -0.01401 31  ARG A CB  
218  C CG  . ARG A 31  ? 0.88913 0.70330 0.77975 -0.04184 -0.09539 -0.01588 31  ARG A CG  
219  C CD  . ARG A 31  ? 0.95454 0.81419 0.87933 -0.05867 -0.09480 0.00097  31  ARG A CD  
220  N NE  . ARG A 31  ? 1.01697 0.89800 0.94865 -0.06150 -0.09350 0.00032  31  ARG A NE  
221  C CZ  . ARG A 31  ? 1.03828 0.92367 0.97706 -0.07911 -0.10915 0.01096  31  ARG A CZ  
222  N NH1 . ARG A 31  ? 0.91406 0.78413 0.85520 -0.09876 -0.12907 0.02466  31  ARG A NH1 
223  N NH2 . ARG A 31  ? 0.82353 0.73011 0.76857 -0.07824 -0.10628 0.01006  31  ARG A NH2 
224  N N   . GLN A 32  ? 0.73816 0.53084 0.62116 0.00191  -0.07164 -0.01763 32  GLN A N   
225  C CA  . GLN A 32  ? 0.82355 0.59189 0.69736 0.01126  -0.07482 -0.01468 32  GLN A CA  
226  C C   . GLN A 32  ? 0.73049 0.53778 0.62815 0.01774  -0.06071 -0.00764 32  GLN A C   
227  O O   . GLN A 32  ? 0.70852 0.50182 0.60158 0.02768  -0.06164 -0.00395 32  GLN A O   
228  C CB  . GLN A 32  ? 0.82569 0.54987 0.66335 0.03540  -0.07561 -0.02775 32  GLN A CB  
229  C CG  . GLN A 32  ? 1.08759 0.77246 0.89463 0.03191  -0.08890 -0.03812 32  GLN A CG  
230  C CD  . GLN A 32  ? 1.25357 0.89289 1.01682 0.06121  -0.08768 -0.05252 32  GLN A CD  
231  O OE1 . GLN A 32  ? 1.24914 0.85960 0.99514 0.07920  -0.08836 -0.05330 32  GLN A OE1 
232  N NE2 . GLN A 32  ? 1.28927 0.92190 1.03199 0.06864  -0.08526 -0.06335 32  GLN A NE2 
233  N N   . ALA A 33  ? 0.58715 0.43908 0.50737 0.01222  -0.04989 -0.00534 33  ALA A N   
234  C CA  . ALA A 33  ? 0.57079 0.45591 0.50846 0.01768  -0.03922 -0.00029 33  ALA A CA  
235  C C   . ALA A 33  ? 0.62186 0.52292 0.57321 0.00416  -0.04263 0.01219  33  ALA A C   
236  O O   . ALA A 33  ? 0.63571 0.53931 0.59130 -0.01084 -0.04873 0.01851  33  ALA A O   
237  C CB  . ALA A 33  ? 0.49929 0.41577 0.44726 0.01893  -0.02880 -0.00494 33  ALA A CB  
238  N N   . ASP A 34  ? 0.54600 0.46188 0.50493 0.00995  -0.03853 0.01791  34  ASP A N   
239  C CA  . ASP A 34  ? 0.61820 0.55462 0.58706 -0.00032 -0.03927 0.02934  34  ASP A CA  
240  C C   . ASP A 34  ? 0.70795 0.67487 0.68324 -0.00492 -0.03219 0.02737  34  ASP A C   
241  O O   . ASP A 34  ? 0.56108 0.54477 0.53968 -0.01208 -0.03155 0.03612  34  ASP A O   
242  C CB  . ASP A 34  ? 0.62200 0.56397 0.59395 0.00738  -0.03872 0.03595  34  ASP A CB  
243  C CG  . ASP A 34  ? 0.73231 0.64175 0.69535 0.01668  -0.04517 0.03833  34  ASP A CG  
244  O OD1 . ASP A 34  ? 0.71600 0.59255 0.66722 0.01267  -0.05378 0.03715  34  ASP A OD1 
245  O OD2 . ASP A 34  ? 0.61372 0.52863 0.58005 0.02846  -0.04317 0.04218  34  ASP A OD2 
246  N N   . ALA A 35  ? 0.53046 0.50366 0.50524 0.00069  -0.02686 0.01715  35  ALA A N   
247  C CA  . ALA A 35  ? 0.56917 0.56213 0.54476 -0.00124 -0.02207 0.01356  35  ALA A CA  
248  C C   . ALA A 35  ? 0.56346 0.55519 0.53844 0.00368  -0.01898 0.00408  35  ALA A C   
249  O O   . ALA A 35  ? 0.52475 0.50983 0.50057 0.01095  -0.01818 0.00253  35  ALA A O   
250  C CB  . ALA A 35  ? 0.55526 0.56235 0.52901 -0.00036 -0.02181 0.01777  35  ALA A CB  
251  N N   . LEU A 36  ? 0.47234 0.47197 0.44509 0.00149  -0.01660 -0.00059 36  LEU A N   
252  C CA  . LEU A 36  ? 0.55153 0.55109 0.52367 0.00397  -0.01450 -0.00739 36  LEU A CA  
253  C C   . LEU A 36  ? 0.58859 0.59524 0.55600 0.00247  -0.01551 -0.00915 36  LEU A C   
254  O O   . LEU A 36  ? 0.51635 0.52463 0.47602 0.00254  -0.01469 -0.01054 36  LEU A O   
255  C CB  . LEU A 36  ? 0.52639 0.51905 0.49598 0.00264  -0.01381 -0.01199 36  LEU A CB  
256  C CG  . LEU A 36  ? 0.61518 0.60897 0.58278 0.00459  -0.01152 -0.01765 36  LEU A CG  
257  C CD1 . LEU A 36  ? 0.56518 0.56009 0.53533 0.01038  -0.00912 -0.01679 36  LEU A CD1 
258  C CD2 . LEU A 36  ? 0.54268 0.53011 0.50671 0.00294  -0.01233 -0.02112 36  LEU A CD2 
259  N N   . TYR A 37  ? 0.52909 0.53920 0.49965 0.00184  -0.01822 -0.00778 37  TYR A N   
260  C CA  . TYR A 37  ? 0.46120 0.46906 0.42327 -0.00221 -0.02420 -0.00932 37  TYR A CA  
261  C C   . TYR A 37  ? 0.47147 0.47805 0.43644 -0.00437 -0.02450 -0.01100 37  TYR A C   
262  O O   . TYR A 37  ? 0.50695 0.52364 0.48469 -0.00364 -0.02188 -0.00589 37  TYR A O   
263  C CB  . TYR A 37  ? 0.43463 0.44796 0.39921 -0.00641 -0.03211 -0.00233 37  TYR A CB  
264  C CG  . TYR A 37  ? 0.53453 0.54766 0.49154 -0.00481 -0.03354 -0.00004 37  TYR A CG  
265  C CD1 . TYR A 37  ? 0.50736 0.52678 0.47476 -0.00128 -0.02921 0.00548  37  TYR A CD1 
266  C CD2 . TYR A 37  ? 0.47106 0.47434 0.40650 -0.00562 -0.04004 -0.00302 37  TYR A CD2 
267  C CE1 . TYR A 37  ? 0.40702 0.42756 0.36824 -0.00084 -0.03087 0.01014  37  TYR A CE1 
268  C CE2 . TYR A 37  ? 0.56816 0.57360 0.49435 -0.00304 -0.04045 0.00054  37  TYR A CE2 
269  C CZ  . TYR A 37  ? 0.61589 0.63241 0.55750 -0.00178 -0.03561 0.00825  37  TYR A CZ  
270  O OH  . TYR A 37  ? 0.56844 0.58833 0.50168 -0.00021 -0.03626 0.01421  37  TYR A OH  
271  N N   . ILE A 38  ? 0.45502 0.44979 0.40672 -0.00492 -0.02698 -0.01692 38  ILE A N   
272  C CA  . ILE A 38  ? 0.44936 0.43910 0.40078 -0.00827 -0.02946 -0.01748 38  ILE A CA  
273  C C   . ILE A 38  ? 0.50127 0.47615 0.43974 -0.01560 -0.04279 -0.01646 38  ILE A C   
274  O O   . ILE A 38  ? 0.55255 0.50780 0.46818 -0.01140 -0.04711 -0.02375 38  ILE A O   
275  C CB  . ILE A 38  ? 0.50583 0.48883 0.45007 -0.00256 -0.02430 -0.02425 38  ILE A CB  
276  C CG1 . ILE A 38  ? 0.46341 0.45595 0.41645 0.00153  -0.01616 -0.02463 38  ILE A CG1 
277  C CG2 . ILE A 38  ? 0.43359 0.41181 0.37827 -0.00594 -0.02666 -0.02329 38  ILE A CG2 
278  C CD1 . ILE A 38  ? 0.47572 0.46684 0.42587 0.00484  -0.01320 -0.02806 38  ILE A CD1 
279  N N   . LEU A 39  ? 0.47350 0.51398 0.51209 0.01828  0.01261  -0.01846 39  LEU A N   
280  C CA  . LEU A 39  ? 0.40634 0.45589 0.45958 0.01598  0.00482  -0.02232 39  LEU A CA  
281  C C   . LEU A 39  ? 0.48820 0.53401 0.54774 0.01207  0.00895  -0.02597 39  LEU A C   
282  O O   . LEU A 39  ? 0.54886 0.59948 0.62945 0.00963  0.00886  -0.02687 39  LEU A O   
283  C CB  . LEU A 39  ? 0.51540 0.57482 0.59160 0.01797  0.00229  -0.01898 39  LEU A CB  
284  C CG  . LEU A 39  ? 0.54643 0.60848 0.61949 0.02336  -0.00083 -0.01330 39  LEU A CG  
285  C CD1 . LEU A 39  ? 0.45870 0.53372 0.55869 0.02611  -0.00523 -0.00967 39  LEU A CD1 
286  C CD2 . LEU A 39  ? 0.42242 0.48507 0.47516 0.02380  -0.01009 -0.01433 39  LEU A CD2 
287  N N   . GLY A 40  ? 0.47382 0.51139 0.51729 0.01146  0.01266  -0.02732 40  GLY A N   
288  C CA  . GLY A 40  ? 0.41638 0.44930 0.46416 0.00869  0.01528  -0.03025 40  GLY A CA  
289  C C   . GLY A 40  ? 0.49450 0.52047 0.54544 0.00889  0.02647  -0.02528 40  GLY A C   
290  O O   . GLY A 40  ? 0.47711 0.50315 0.53233 0.01054  0.03263  -0.02088 40  GLY A O   
291  N N   . ASP A 41  ? 0.43766 0.45674 0.48576 0.00783  0.02965  -0.02578 41  ASP A N   
292  C CA  . ASP A 41  ? 0.47802 0.48926 0.52506 0.00847  0.03999  -0.02004 41  ASP A CA  
293  C C   . ASP A 41  ? 0.42419 0.43161 0.45130 0.01150  0.04394  -0.01624 41  ASP A C   
294  O O   . ASP A 41  ? 0.44459 0.44714 0.46876 0.01267  0.05262  -0.01163 41  ASP A O   
295  C CB  . ASP A 41  ? 0.41490 0.42765 0.48319 0.00663  0.04698  -0.01679 41  ASP A CB  
296  C CG  . ASP A 41  ? 0.54996 0.56255 0.63886 0.00204  0.04555  -0.01953 41  ASP A CG  
297  O OD1 . ASP A 41  ? 0.40546 0.41559 0.49068 0.00074  0.03865  -0.02528 41  ASP A OD1 
298  O OD2 . ASP A 41  ? 0.56438 0.57875 0.67417 -0.00042 0.05224  -0.01615 41  ASP A OD2 
299  N N   . LEU A 42  ? 0.44956 0.45882 0.46254 0.01243  0.03797  -0.01851 42  LEU A N   
300  C CA  . LEU A 42  ? 0.44644 0.45161 0.44129 0.01377  0.04019  -0.01603 42  LEU A CA  
301  C C   . LEU A 42  ? 0.52740 0.52639 0.51418 0.01479  0.04441  -0.01216 42  LEU A C   
302  O O   . LEU A 42  ? 0.46860 0.46203 0.44420 0.01570  0.04973  -0.00884 42  LEU A O   
303  C CB  . LEU A 42  ? 0.51769 0.52715 0.50304 0.01358  0.03327  -0.01861 42  LEU A CB  
304  C CG  . LEU A 42  ? 0.51972 0.52685 0.48928 0.01322  0.03315  -0.01731 42  LEU A CG  
305  C CD1 . LEU A 42  ? 0.43318 0.43432 0.39794 0.01311  0.03787  -0.01653 42  LEU A CD1 
306  C CD2 . LEU A 42  ? 0.39420 0.40725 0.36003 0.01232  0.02744  -0.01912 42  LEU A CD2 
307  N N   . PHE A 43  ? 0.38256 0.38136 0.37411 0.01520  0.04241  -0.01238 43  PHE A N   
308  C CA  . PHE A 43  ? 0.45467 0.44754 0.44033 0.01733  0.04583  -0.00709 43  PHE A CA  
309  C C   . PHE A 43  ? 0.56200 0.54891 0.56206 0.01677  0.05198  -0.00435 43  PHE A C   
310  O O   . PHE A 43  ? 0.44497 0.43374 0.46172 0.01417  0.05050  -0.00882 43  PHE A O   
311  C CB  . PHE A 43  ? 0.46387 0.45977 0.44561 0.01943  0.04015  -0.00801 43  PHE A CB  
312  C CG  . PHE A 43  ? 0.46858 0.47125 0.43924 0.01912  0.03479  -0.00968 43  PHE A CG  
313  C CD1 . PHE A 43  ? 0.49239 0.49483 0.44929 0.01971  0.03389  -0.00580 43  PHE A CD1 
314  C CD2 . PHE A 43  ? 0.44520 0.45429 0.41885 0.01774  0.03049  -0.01499 43  PHE A CD2 
315  C CE1 . PHE A 43  ? 0.49332 0.50212 0.44303 0.01787  0.02861  -0.00782 43  PHE A CE1 
316  C CE2 . PHE A 43  ? 0.43564 0.45039 0.40133 0.01666  0.02688  -0.01557 43  PHE A CE2 
317  C CZ  . PHE A 43  ? 0.43796 0.45273 0.39342 0.01620  0.02588  -0.01229 43  PHE A CZ  
318  N N   . GLU A 44  ? 0.46027 0.43971 0.45332 0.01894  0.05847  0.00331  44  GLU A N   
319  C CA  . GLU A 44  ? 0.46437 0.43631 0.47118 0.01826  0.06605  0.00792  44  GLU A CA  
320  C C   . GLU A 44  ? 0.54904 0.51760 0.56702 0.01855  0.06268  0.00564  44  GLU A C   
321  O O   . GLU A 44  ? 0.60101 0.56388 0.63685 0.01576  0.06686  0.00561  44  GLU A O   
322  C CB  . GLU A 44  ? 0.67388 0.63761 0.66636 0.02139  0.07453  0.01826  44  GLU A CB  
323  C CG  . GLU A 44  ? 0.64856 0.60240 0.65352 0.02132  0.08364  0.02581  44  GLU A CG  
324  C CD  . GLU A 44  ? 0.93190 0.88575 0.95598 0.01697  0.09280  0.02619  44  GLU A CD  
325  O OE1 . GLU A 44  ? 0.82176 0.78446 0.85260 0.01451  0.09031  0.01959  44  GLU A OE1 
326  O OE2 . GLU A 44  ? 0.96517 0.91069 0.99989 0.01609  0.10264  0.03376  44  GLU A OE2 
327  N N   . ALA A 45  ? 0.52271 0.49427 0.53202 0.02171  0.05586  0.00336  45  ALA A N   
328  C CA  . ALA A 45  ? 0.57494 0.54214 0.59326 0.02344  0.05385  0.00044  45  ALA A CA  
329  C C   . ALA A 45  ? 0.51860 0.49444 0.52944 0.02589  0.04629  -0.00514 45  ALA A C   
330  O O   . ALA A 45  ? 0.70955 0.69353 0.70788 0.02663  0.04285  -0.00391 45  ALA A O   
331  C CB  . ALA A 45  ? 0.39698 0.35347 0.41453 0.02807  0.05943  0.01043  45  ALA A CB  
332  N N   . TRP A 46  ? 0.53618 0.50947 0.55512 0.02683  0.04447  -0.01174 46  TRP A N   
333  C CA  . TRP A 46  ? 0.64856 0.62955 0.66149 0.03012  0.03982  -0.01625 46  TRP A CA  
334  C C   . TRP A 46  ? 0.57924 0.55193 0.60051 0.03369  0.04167  -0.02072 46  TRP A C   
335  O O   . TRP A 46  ? 0.55069 0.51481 0.58130 0.03026  0.04258  -0.02767 46  TRP A O   
336  C CB  . TRP A 46  ? 0.45357 0.44371 0.46240 0.02624  0.03487  -0.02402 46  TRP A CB  
337  C CG  . TRP A 46  ? 0.57982 0.57988 0.58017 0.02903  0.03176  -0.02553 46  TRP A CG  
338  C CD1 . TRP A 46  ? 0.52167 0.52328 0.52208 0.03180  0.03138  -0.03188 46  TRP A CD1 
339  C CD2 . TRP A 46  ? 0.54557 0.55505 0.53697 0.02882  0.02955  -0.02082 46  TRP A CD2 
340  N NE1 . TRP A 46  ? 0.53389 0.54676 0.52771 0.03347  0.02999  -0.03007 46  TRP A NE1 
341  C CE2 . TRP A 46  ? 0.48453 0.50230 0.47381 0.03105  0.02814  -0.02353 46  TRP A CE2 
342  C CE3 . TRP A 46  ? 0.58371 0.59451 0.56838 0.02662  0.02912  -0.01530 46  TRP A CE3 
343  C CZ2 . TRP A 46  ? 0.45376 0.48191 0.43766 0.03012  0.02582  -0.02029 46  TRP A CZ2 
344  C CZ3 . TRP A 46  ? 0.48825 0.50774 0.46522 0.02575  0.02587  -0.01351 46  TRP A CZ3 
345  C CH2 . TRP A 46  ? 0.47912 0.50758 0.45735 0.02698  0.02400  -0.01572 46  TRP A CH2 
346  N N   . ILE A 47  ? 0.61553 0.59053 0.63483 0.04054  0.04220  -0.01701 47  ILE A N   
347  C CA  . ILE A 47  ? 0.54241 0.50836 0.56974 0.04571  0.04551  -0.02103 47  ILE A CA  
348  C C   . ILE A 47  ? 0.62265 0.59838 0.64619 0.05006  0.04425  -0.02650 47  ILE A C   
349  O O   . ILE A 47  ? 0.56766 0.53791 0.59703 0.05668  0.04817  -0.02846 47  ILE A O   
350  C CB  . ILE A 47  ? 0.52759 0.48433 0.56098 0.05216  0.04999  -0.00984 47  ILE A CB  
351  C CG1 . ILE A 47  ? 0.63706 0.60688 0.66333 0.05721  0.04680  0.00100  47  ILE A CG1 
352  C CG2 . ILE A 47  ? 0.51211 0.45659 0.55014 0.04772  0.05385  -0.00456 47  ILE A CG2 
353  C CD1 . ILE A 47  ? 0.62546 0.58919 0.65742 0.06612  0.04953  0.01236  47  ILE A CD1 
354  N N   . GLY A 48  ? 0.59276 0.58206 0.60742 0.04680  0.04014  -0.02863 48  GLY A N   
355  C CA  . GLY A 48  ? 0.51094 0.51027 0.52211 0.05015  0.04048  -0.03292 48  GLY A CA  
356  C C   . GLY A 48  ? 0.53789 0.55351 0.54516 0.04964  0.03728  -0.02563 48  GLY A C   
357  O O   . GLY A 48  ? 0.54579 0.56431 0.55359 0.04965  0.03494  -0.01672 48  GLY A O   
358  N N   . ASP A 49  ? 0.46820 0.49399 0.47073 0.04893  0.03728  -0.02955 49  ASP A N   
359  C CA  . ASP A 49  ? 0.47864 0.51915 0.47905 0.04645  0.03425  -0.02382 49  ASP A CA  
360  C C   . ASP A 49  ? 0.62092 0.67233 0.63161 0.05197  0.03447  -0.01625 49  ASP A C   
361  O O   . ASP A 49  ? 0.57918 0.64325 0.59053 0.04893  0.03063  -0.01137 49  ASP A O   
362  C CB  . ASP A 49  ? 0.49725 0.54472 0.49076 0.04404  0.03553  -0.02878 49  ASP A CB  
363  C CG  . ASP A 49  ? 0.48148 0.52169 0.46477 0.03866  0.03299  -0.03459 49  ASP A CG  
364  O OD1 . ASP A 49  ? 0.58333 0.61540 0.56700 0.03559  0.03015  -0.03451 49  ASP A OD1 
365  O OD2 . ASP A 49  ? 0.56649 0.60987 0.54182 0.03801  0.03418  -0.03870 49  ASP A OD2 
366  N N   . ASP A 50  ? 0.44881 0.49596 0.46902 0.05997  0.03847  -0.01518 50  ASP A N   
367  C CA  . ASP A 50  ? 0.44244 0.50181 0.47528 0.06640  0.03770  -0.00658 50  ASP A CA  
368  C C   . ASP A 50  ? 0.52811 0.58477 0.56118 0.06726  0.03210  0.00293  50  ASP A C   
369  O O   . ASP A 50  ? 0.45091 0.51799 0.49413 0.07309  0.02934  0.01137  50  ASP A O   
370  C CB  . ASP A 50  ? 0.50146 0.55834 0.54617 0.07665  0.04557  -0.00860 50  ASP A CB  
371  C CG  . ASP A 50  ? 0.70522 0.73950 0.74734 0.07908  0.05022  -0.01494 50  ASP A CG  
372  O OD1 . ASP A 50  ? 0.60573 0.62821 0.63965 0.07284  0.04723  -0.01647 50  ASP A OD1 
373  O OD2 . ASP A 50  ? 0.75271 0.78070 0.80299 0.08740  0.05741  -0.01826 50  ASP A OD2 
374  N N   . ASP A 51  ? 0.45164 0.49518 0.47407 0.06222  0.03070  0.00232  51  ASP A N   
375  C CA  . ASP A 51  ? 0.52405 0.56385 0.54191 0.06262  0.02667  0.01158  51  ASP A CA  
376  C C   . ASP A 51  ? 0.61145 0.66699 0.62447 0.05907  0.01841  0.01656  51  ASP A C   
377  O O   . ASP A 51  ? 0.55992 0.61960 0.56541 0.05134  0.01621  0.01164  51  ASP A O   
378  C CB  . ASP A 51  ? 0.42203 0.44634 0.43026 0.05693  0.02886  0.00880  51  ASP A CB  
379  C CG  . ASP A 51  ? 0.59156 0.60827 0.59328 0.05827  0.02799  0.01867  51  ASP A CG  
380  O OD1 . ASP A 51  ? 0.52572 0.55004 0.52649 0.06288  0.02331  0.02773  51  ASP A OD1 
381  O OD2 . ASP A 51  ? 0.64076 0.64454 0.63824 0.05464  0.03202  0.01777  51  ASP A OD2 
382  N N   . PRO A 52  ? 0.64186 0.70590 0.65907 0.06428  0.01307  0.02607  52  PRO A N   
383  C CA  . PRO A 52  ? 0.54954 0.62940 0.56279 0.05979  0.00335  0.02931  52  PRO A CA  
384  C C   . PRO A 52  ? 0.59781 0.66970 0.59047 0.05436  -0.00132 0.03139  52  PRO A C   
385  O O   . PRO A 52  ? 0.49421 0.57634 0.48043 0.05128  -0.01063 0.03434  52  PRO A O   
386  C CB  . PRO A 52  ? 0.51448 0.60813 0.54261 0.06874  -0.00143 0.03887  52  PRO A CB  
387  C CG  . PRO A 52  ? 0.46792 0.54584 0.49806 0.07768  0.00469  0.04417  52  PRO A CG  
388  C CD  . PRO A 52  ? 0.51421 0.57532 0.54260 0.07503  0.01511  0.03406  52  PRO A CD  
389  N N   . ASN A 53  ? 0.47472 0.52865 0.45742 0.05307  0.00525  0.02949  53  ASN A N   
390  C CA  . ASN A 53  ? 0.56643 0.61114 0.52936 0.04853  0.00419  0.03077  53  ASN A CA  
391  C C   . ASN A 53  ? 0.51616 0.56900 0.47024 0.04019  -0.00196 0.02500  53  ASN A C   
392  O O   . ASN A 53  ? 0.48878 0.54311 0.44773 0.03521  0.00063  0.01718  53  ASN A O   
393  C CB  . ASN A 53  ? 0.49062 0.51861 0.45094 0.04643  0.01372  0.02684  53  ASN A CB  
394  C CG  . ASN A 53  ? 0.68831 0.70595 0.62971 0.04330  0.01574  0.02931  53  ASN A CG  
395  O OD1 . ASN A 53  ? 0.60173 0.62339 0.52783 0.04094  0.00972  0.03061  53  ASN A OD1 
396  N ND2 . ASN A 53  ? 0.54653 0.55089 0.48945 0.04267  0.02465  0.02883  53  ASN A ND2 
397  N N   . PRO A 54  ? 0.61275 0.66996 0.55316 0.03840  -0.01034 0.02849  54  PRO A N   
398  C CA  . PRO A 54  ? 0.58527 0.64933 0.51945 0.02971  -0.01679 0.02188  54  PRO A CA  
399  C C   . PRO A 54  ? 0.61946 0.67071 0.54379 0.02350  -0.01012 0.01393  54  PRO A C   
400  O O   . PRO A 54  ? 0.49057 0.54587 0.41837 0.01703  -0.01152 0.00748  54  PRO A O   
401  C CB  . PRO A 54  ? 0.53113 0.59827 0.44815 0.02955  -0.02712 0.02665  54  PRO A CB  
402  C CG  . PRO A 54  ? 0.50007 0.57056 0.42283 0.03966  -0.02862 0.03798  54  PRO A CG  
403  C CD  . PRO A 54  ? 0.60441 0.66113 0.53473 0.04435  -0.01539 0.03876  54  PRO A CD  
404  N N   . LEU A 55  ? 0.44650 0.48268 0.36077 0.02563  -0.00226 0.01514  55  LEU A N   
405  C CA  . LEU A 55  ? 0.52873 0.55403 0.43687 0.02105  0.00460  0.00859  55  LEU A CA  
406  C C   . LEU A 55  ? 0.53719 0.56671 0.46137 0.01864  0.00715  0.00289  55  LEU A C   
407  O O   . LEU A 55  ? 0.53696 0.56394 0.45833 0.01352  0.00806  -0.00273 55  LEU A O   
408  C CB  . LEU A 55  ? 0.67025 0.68190 0.57286 0.02454  0.01402  0.01217  55  LEU A CB  
409  C CG  . LEU A 55  ? 0.76849 0.77064 0.67036 0.02137  0.02231  0.00678  55  LEU A CG  
410  C CD1 . LEU A 55  ? 0.64025 0.63770 0.52450 0.01687  0.02114  0.00188  55  LEU A CD1 
411  C CD2 . LEU A 55  ? 0.58112 0.57294 0.48385 0.02473  0.03200  0.01168  55  LEU A CD2 
412  N N   . HIS A 56  ? 0.54445 0.57942 0.48414 0.02278  0.00858  0.00438  56  HIS A N   
413  C CA  . HIS A 56  ? 0.59940 0.63839 0.55043 0.02109  0.01084  -0.00092 56  HIS A CA  
414  C C   . HIS A 56  ? 0.53320 0.58243 0.48583 0.01600  0.00601  -0.00333 56  HIS A C   
415  O O   . HIS A 56  ? 0.61724 0.66514 0.57054 0.01215  0.00810  -0.00752 56  HIS A O   
416  C CB  . HIS A 56  ? 0.59000 0.63228 0.55454 0.02691  0.01332  0.00014  56  HIS A CB  
417  C CG  . HIS A 56  ? 0.63520 0.66569 0.60130 0.03059  0.01863  0.00169  56  HIS A CG  
418  N ND1 . HIS A 56  ? 0.55996 0.58859 0.53701 0.03594  0.02158  0.00207  56  HIS A ND1 
419  C CD2 . HIS A 56  ? 0.57255 0.59188 0.53209 0.02937  0.02246  0.00295  56  HIS A CD2 
420  C CE1 . HIS A 56  ? 0.50489 0.52115 0.48276 0.03693  0.02626  0.00345  56  HIS A CE1 
421  N NE2 . HIS A 56  ? 0.61768 0.62923 0.58579 0.03301  0.02717  0.00454  56  HIS A NE2 
422  N N   . GLN A 57  ? 0.56098 0.62084 0.51550 0.01573  -0.00077 -0.00003 57  GLN A N   
423  C CA  . GLN A 57  ? 0.55472 0.62511 0.51447 0.00956  -0.00528 -0.00215 57  GLN A CA  
424  C C   . GLN A 57  ? 0.54230 0.60352 0.48817 0.00216  -0.00710 -0.00659 57  GLN A C   
425  O O   . GLN A 57  ? 0.53376 0.59485 0.48278 -0.00331 -0.00576 -0.01000 57  GLN A O   
426  C CB  . GLN A 57  ? 0.62435 0.71105 0.59378 0.01077  -0.01321 0.00257  57  GLN A CB  
427  C CG  . GLN A 57  ? 0.73699 0.83484 0.72504 0.01783  -0.00974 0.00604  57  GLN A CG  
428  C CD  . GLN A 57  ? 1.04465 1.14082 1.03863 0.01744  -0.00117 0.00180  57  GLN A CD  
429  O OE1 . GLN A 57  ? 1.08797 1.17642 1.08188 0.02286  0.00522  0.00043  57  GLN A OE1 
430  N NE2 . GLN A 57  ? 0.88249 0.98488 0.88050 0.01066  -0.00123 -0.00029 57  GLN A NE2 
431  N N   . GLN A 58  ? 0.52513 0.57725 0.45463 0.00235  -0.00919 -0.00635 58  GLN A N   
432  C CA  . GLN A 58  ? 0.58196 0.62235 0.49594 -0.00363 -0.00932 -0.01179 58  GLN A CA  
433  C C   . GLN A 58  ? 0.55212 0.58195 0.46740 -0.00425 -0.00066 -0.01528 58  GLN A C   
434  O O   . GLN A 58  ? 0.49667 0.52164 0.41036 -0.00986 -0.00031 -0.01959 58  GLN A O   
435  C CB  . GLN A 58  ? 0.57453 0.60528 0.46798 -0.00126 -0.01013 -0.01055 58  GLN A CB  
436  C CG  . GLN A 58  ? 0.74172 0.78218 0.62885 -0.00234 -0.02176 -0.00805 58  GLN A CG  
437  C CD  . GLN A 58  ? 0.89350 0.92794 0.76308 0.00377  -0.02188 -0.00233 58  GLN A CD  
438  O OE1 . GLN A 58  ? 0.73113 0.75263 0.59272 0.00776  -0.01194 -0.00088 58  GLN A OE1 
439  N NE2 . GLN A 58  ? 0.72301 0.76772 0.58755 0.00465  -0.03322 0.00191  58  GLN A NE2 
440  N N   . ILE A 59  ? 0.51775 0.54394 0.43728 0.00139  0.00588  -0.01320 59  ILE A N   
441  C CA  . ILE A 59  ? 0.56350 0.58221 0.48612 0.00141  0.01239  -0.01576 59  ILE A CA  
442  C C   . ILE A 59  ? 0.51321 0.53919 0.44686 -0.00088 0.01171  -0.01661 59  ILE A C   
443  O O   . ILE A 59  ? 0.50739 0.52766 0.44031 -0.00362 0.01396  -0.01865 59  ILE A O   
444  C CB  . ILE A 59  ? 0.50886 0.52394 0.43604 0.00688  0.01794  -0.01366 59  ILE A CB  
445  C CG1 . ILE A 59  ? 0.53548 0.54082 0.45054 0.00862  0.02166  -0.01200 59  ILE A CG1 
446  C CG2 . ILE A 59  ? 0.40047 0.41264 0.33517 0.00703  0.02206  -0.01592 59  ILE A CG2 
447  C CD1 . ILE A 59  ? 0.45814 0.45296 0.36087 0.00571  0.02481  -0.01592 59  ILE A CD1 
448  N N   . ALA A 60  ? 0.45236 0.49041 0.39603 0.00087  0.00956  -0.01436 60  ALA A N   
449  C CA  . ALA A 60  ? 0.44525 0.49042 0.39762 -0.00064 0.01073  -0.01435 60  ALA A CA  
450  C C   . ALA A 60  ? 0.50788 0.55373 0.45999 -0.00792 0.00848  -0.01511 60  ALA A C   
451  O O   . ALA A 60  ? 0.52620 0.56942 0.47997 -0.01018 0.01156  -0.01502 60  ALA A O   
452  C CB  . ALA A 60  ? 0.37264 0.43055 0.33560 0.00324  0.01046  -0.01206 60  ALA A CB  
453  N N   . SER A 61  ? 0.44501 0.49378 0.39486 -0.01192 0.00264  -0.01567 61  SER A N   
454  C CA  . SER A 61  ? 0.50703 0.55568 0.45839 -0.02044 -0.00033 -0.01760 61  SER A CA  
455  C C   . SER A 61  ? 0.49627 0.52678 0.43604 -0.02347 0.00272  -0.02166 61  SER A C   
456  O O   . SER A 61  ? 0.56077 0.58681 0.50386 -0.02915 0.00415  -0.02250 61  SER A O   
457  C CB  . SER A 61  ? 0.40659 0.46418 0.35872 -0.02454 -0.00954 -0.01816 61  SER A CB  
458  N N   . ALA A 62  ? 0.56476 0.58410 0.49241 -0.01927 0.00514  -0.02354 62  ALA A N   
459  C CA  . ALA A 62  ? 0.64164 0.64379 0.55976 -0.02086 0.00946  -0.02743 62  ALA A CA  
460  C C   . ALA A 62  ? 0.47156 0.47011 0.39700 -0.01805 0.01555  -0.02491 62  ALA A C   
461  O O   . ALA A 62  ? 0.56954 0.55724 0.49399 -0.02090 0.01838  -0.02621 62  ALA A O   
462  C CB  . ALA A 62  ? 0.44669 0.43910 0.35093 -0.01665 0.01213  -0.02943 62  ALA A CB  
463  N N   . ILE A 63  ? 0.52867 0.53551 0.46101 -0.01237 0.01711  -0.02133 63  ILE A N   
464  C CA  . ILE A 63  ? 0.58671 0.59239 0.52445 -0.00952 0.02070  -0.01863 63  ILE A CA  
465  C C   . ILE A 63  ? 0.51441 0.52476 0.45750 -0.01364 0.02052  -0.01572 63  ILE A C   
466  O O   . ILE A 63  ? 0.57862 0.58150 0.52206 -0.01430 0.02344  -0.01349 63  ILE A O   
467  C CB  . ILE A 63  ? 0.61057 0.62348 0.55270 -0.00336 0.02107  -0.01725 63  ILE A CB  
468  C CG1 . ILE A 63  ? 0.52216 0.52904 0.46159 -0.00005 0.02308  -0.01893 63  ILE A CG1 
469  C CG2 . ILE A 63  ? 0.44592 0.46018 0.39173 -0.00061 0.02232  -0.01463 63  ILE A CG2 
470  C CD1 . ILE A 63  ? 0.51616 0.52899 0.46204 0.00446  0.02307  -0.01837 63  ILE A CD1 
471  N N   . LYS A 64  ? 0.52182 0.54465 0.47044 -0.01609 0.01787  -0.01471 64  LYS A N   
472  C CA  . LYS A 64  ? 0.52093 0.54973 0.47684 -0.02048 0.01937  -0.01111 64  LYS A CA  
473  C C   . LYS A 64  ? 0.49544 0.51289 0.45093 -0.02803 0.01981  -0.01203 64  LYS A C   
474  O O   . LYS A 64  ? 0.50391 0.51914 0.46368 -0.03074 0.02367  -0.00763 64  LYS A O   
475  C CB  . LYS A 64  ? 0.51539 0.56088 0.48069 -0.02189 0.01678  -0.01013 64  LYS A CB  
476  C CG  . LYS A 64  ? 0.50979 0.56422 0.48601 -0.02673 0.01986  -0.00571 64  LYS A CG  
477  C CD  . LYS A 64  ? 0.63973 0.69602 0.61385 -0.02143 0.02656  -0.00121 64  LYS A CD  
478  C CE  . LYS A 64  ? 0.64880 0.72071 0.63432 -0.02236 0.03102  0.00314  64  LYS A CE  
479  N NZ  . LYS A 64  ? 0.78566 0.85506 0.77573 -0.02868 0.03639  0.00878  64  LYS A NZ  
480  N N   . ALA A 65  ? 0.46035 0.46889 0.40942 -0.03148 0.01646  -0.01773 65  ALA A N   
481  C CA  . ALA A 65  ? 0.54297 0.53718 0.49027 -0.03890 0.01705  -0.02067 65  ALA A CA  
482  C C   . ALA A 65  ? 0.65904 0.63730 0.60275 -0.03498 0.02357  -0.01857 65  ALA A C   
483  O O   . ALA A 65  ? 0.55705 0.52509 0.50427 -0.03963 0.02669  -0.01671 65  ALA A O   
484  C CB  . ALA A 65  ? 0.59692 0.58391 0.53387 -0.04278 0.01184  -0.02873 65  ALA A CB  
485  N N   . VAL A 66  ? 0.53857 0.51466 0.47729 -0.02645 0.02567  -0.01823 66  VAL A N   
486  C CA  . VAL A 66  ? 0.57782 0.54269 0.51654 -0.02121 0.03084  -0.01483 66  VAL A CA  
487  C C   . VAL A 66  ? 0.56066 0.53208 0.50537 -0.01967 0.03243  -0.00643 66  VAL A C   
488  O O   . VAL A 66  ? 0.56773 0.52847 0.51394 -0.01954 0.03619  -0.00171 66  VAL A O   
489  C CB  . VAL A 66  ? 0.65084 0.61624 0.58708 -0.01297 0.03193  -0.01599 66  VAL A CB  
490  C CG1 . VAL A 66  ? 0.54357 0.50190 0.48388 -0.00659 0.03585  -0.01127 66  VAL A CG1 
491  C CG2 . VAL A 66  ? 0.60522 0.56202 0.53259 -0.01395 0.03264  -0.02323 66  VAL A CG2 
492  N N   . VAL A 67  ? 0.55149 0.53937 0.49837 -0.01790 0.03026  -0.00419 67  VAL A N   
493  C CA  . VAL A 67  ? 0.53044 0.52523 0.47898 -0.01603 0.03244  0.00327  67  VAL A CA  
494  C C   . VAL A 67  ? 0.65606 0.64745 0.60964 -0.02366 0.03590  0.00748  67  VAL A C   
495  O O   . VAL A 67  ? 0.56161 0.54854 0.51456 -0.02251 0.04013  0.01535  67  VAL A O   
496  C CB  . VAL A 67  ? 0.61979 0.63136 0.56856 -0.01291 0.03045  0.00250  67  VAL A CB  
497  C CG1 . VAL A 67  ? 0.46253 0.48161 0.41013 -0.01158 0.03403  0.00922  67  VAL A CG1 
498  C CG2 . VAL A 67  ? 0.42157 0.43479 0.36722 -0.00611 0.02745  -0.00116 67  VAL A CG2 
499  N N   . ASP A 68  ? 0.53015 0.52416 0.48949 -0.03183 0.03383  0.00297  68  ASP A N   
500  C CA  . ASP A 68  ? 0.64028 0.63226 0.60855 -0.04100 0.03671  0.00631  68  ASP A CA  
501  C C   . ASP A 68  ? 0.62303 0.59275 0.59009 -0.04476 0.03963  0.00626  68  ASP A C   
502  O O   . ASP A 68  ? 0.62154 0.58559 0.59602 -0.05121 0.04405  0.01154  68  ASP A O   
503  C CB  . ASP A 68  ? 0.49754 0.50066 0.47489 -0.04932 0.03155  0.00090  68  ASP A CB  
504  C CG  . ASP A 68  ? 0.68849 0.71417 0.67245 -0.04627 0.03086  0.00326  68  ASP A CG  
505  O OD1 . ASP A 68  ? 0.62900 0.66095 0.61146 -0.04044 0.03632  0.00954  68  ASP A OD1 
506  O OD2 . ASP A 68  ? 0.63018 0.66690 0.61998 -0.04916 0.02478  -0.00126 68  ASP A OD2 
507  N N   . ALA A 69  ? 0.65748 0.61374 0.61649 -0.04086 0.03841  0.00055  69  ALA A N   
508  C CA  . ALA A 69  ? 0.64709 0.58021 0.60469 -0.04213 0.04263  0.00024  69  ALA A CA  
509  C C   . ALA A 69  ? 0.58548 0.51230 0.54236 -0.03360 0.04781  0.01065  69  ALA A C   
510  O O   . ALA A 69  ? 0.62830 0.53544 0.58516 -0.03209 0.05204  0.01199  69  ALA A O   
511  C CB  . ALA A 69  ? 0.62446 0.54568 0.57338 -0.04022 0.04100  -0.01006 69  ALA A CB  
512  N N   . GLY A 70  ? 0.64315 0.58559 0.59858 -0.02744 0.04718  0.01774  70  GLY A N   
513  C CA  . GLY A 70  ? 0.61367 0.55267 0.56640 -0.01951 0.05014  0.02849  70  GLY A CA  
514  C C   . GLY A 70  ? 0.56822 0.51084 0.51680 -0.00867 0.04667  0.02838  70  GLY A C   
515  O O   . GLY A 70  ? 0.59192 0.53112 0.53892 -0.00157 0.04751  0.03742  70  GLY A O   
516  N N   . VAL A 71  ? 0.63653 0.58667 0.58437 -0.00723 0.04258  0.01942  71  VAL A N   
517  C CA  . VAL A 71  ? 0.59005 0.54401 0.53809 0.00161  0.03969  0.01854  71  VAL A CA  
518  C C   . VAL A 71  ? 0.57438 0.54725 0.51953 0.00395  0.03458  0.01733  71  VAL A C   
519  O O   . VAL A 71  ? 0.48674 0.46693 0.43168 0.00075  0.03281  0.01029  71  VAL A O   
520  C CB  . VAL A 71  ? 0.63380 0.57947 0.58355 0.00173  0.04098  0.00975  71  VAL A CB  
521  C CG1 . VAL A 71  ? 0.56953 0.52169 0.52383 0.01038  0.03902  0.00981  71  VAL A CG1 
522  C CG2 . VAL A 71  ? 0.44802 0.37223 0.39879 -0.00040 0.04680  0.00903  71  VAL A CG2 
523  N N   . PRO A 72  ? 0.57336 0.55357 0.51533 0.00979  0.03178  0.02372  72  PRO A N   
524  C CA  . PRO A 72  ? 0.64189 0.63755 0.57952 0.01171  0.02708  0.02075  72  PRO A CA  
525  C C   . PRO A 72  ? 0.71460 0.71507 0.65795 0.01415  0.02318  0.01326  72  PRO A C   
526  O O   . PRO A 72  ? 0.46198 0.45778 0.41239 0.01776  0.02280  0.01341  72  PRO A O   
527  C CB  . PRO A 72  ? 0.65210 0.65141 0.58228 0.01751  0.02431  0.02919  72  PRO A CB  
528  C CG  . PRO A 72  ? 0.52291 0.51039 0.45810 0.02124  0.02563  0.03636  72  PRO A CG  
529  C CD  . PRO A 72  ? 0.54507 0.51874 0.48581 0.01504  0.03248  0.03411  72  PRO A CD  
530  N N   . CYS A 73  ? 0.44790 0.45767 0.38967 0.01249  0.02130  0.00737  73  CYS A N   
531  C CA  . CYS A 73  ? 0.49489 0.50781 0.44263 0.01335  0.01921  0.00070  73  CYS A CA  
532  C C   . CYS A 73  ? 0.50201 0.52535 0.44784 0.01583  0.01422  -0.00226 73  CYS A C   
533  O O   . CYS A 73  ? 0.53003 0.55850 0.46834 0.01509  0.01446  -0.00276 73  CYS A O   
534  C CB  . CYS A 73  ? 0.60074 0.61155 0.54882 0.00859  0.02208  -0.00404 73  CYS A CB  
535  S SG  . CYS A 73  ? 0.57056 0.56659 0.51909 0.00531  0.02673  -0.00450 73  CYS A SG  
536  N N   . TYR A 74  ? 0.56747 0.59357 0.52110 0.01853  0.01031  -0.00473 74  TYR A N   
537  C CA  . TYR A 74  ? 0.49391 0.52821 0.44694 0.02022  0.00407  -0.00867 74  TYR A CA  
538  C C   . TYR A 74  ? 0.52204 0.55746 0.48625 0.01900  0.00388  -0.01470 74  TYR A C   
539  O O   . TYR A 74  ? 0.48865 0.52024 0.46260 0.01880  0.00732  -0.01398 74  TYR A O   
540  C CB  . TYR A 74  ? 0.49317 0.53165 0.44736 0.02421  -0.00285 -0.00478 74  TYR A CB  
541  C CG  . TYR A 74  ? 0.57121 0.60696 0.51432 0.02641  -0.00216 0.00364  74  TYR A CG  
542  C CD1 . TYR A 74  ? 0.59668 0.63592 0.52335 0.02725  -0.00392 0.00476  74  TYR A CD1 
543  C CD2 . TYR A 74  ? 0.54215 0.57035 0.49065 0.02801  0.00145  0.01074  74  TYR A CD2 
544  C CE1 . TYR A 74  ? 0.58593 0.62202 0.50184 0.02929  -0.00197 0.01403  74  TYR A CE1 
545  C CE2 . TYR A 74  ? 0.53867 0.56246 0.47793 0.03000  0.00285  0.01969  74  TYR A CE2 
546  C CZ  . TYR A 74  ? 0.54923 0.57743 0.47224 0.03048  0.00115  0.02195  74  TYR A CZ  
547  O OH  . TYR A 74  ? 0.62027 0.64362 0.53318 0.03246  0.00380  0.03231  74  TYR A OH  
548  N N   . PHE A 75  ? 0.47618 0.51563 0.43854 0.01845  0.00078  -0.02056 75  PHE A N   
549  C CA  . PHE A 75  ? 0.48445 0.52325 0.45771 0.01688  0.00150  -0.02559 75  PHE A CA  
550  C C   . PHE A 75  ? 0.48902 0.53264 0.46628 0.01671  -0.00594 -0.03153 75  PHE A C   
551  O O   . PHE A 75  ? 0.50224 0.54778 0.46725 0.01750  -0.00960 -0.03509 75  PHE A O   
552  C CB  . PHE A 75  ? 0.49108 0.52665 0.45979 0.01565  0.00670  -0.02755 75  PHE A CB  
553  C CG  . PHE A 75  ? 0.58741 0.62024 0.56613 0.01462  0.00851  -0.03086 75  PHE A CG  
554  C CD1 . PHE A 75  ? 0.45914 0.48815 0.44603 0.01389  0.01285  -0.02800 75  PHE A CD1 
555  C CD2 . PHE A 75  ? 0.51717 0.54966 0.49620 0.01470  0.00703  -0.03664 75  PHE A CD2 
556  C CE1 . PHE A 75  ? 0.49368 0.51936 0.48909 0.01306  0.01578  -0.02930 75  PHE A CE1 
557  C CE2 . PHE A 75  ? 0.42678 0.45478 0.41584 0.01373  0.00950  -0.03851 75  PHE A CE2 
558  C CZ  . PHE A 75  ? 0.48805 0.51300 0.48548 0.01281  0.01393  -0.03409 75  PHE A CZ  
559  N N   . ILE A 76  ? 0.43807 0.48350 0.43244 0.01538  -0.00782 -0.03298 76  ILE A N   
560  C CA  . ILE A 76  ? 0.43681 0.48549 0.43948 0.01309  -0.01456 -0.04028 76  ILE A CA  
561  C C   . ILE A 76  ? 0.51608 0.55855 0.52912 0.01045  -0.00831 -0.04307 76  ILE A C   
562  O O   . ILE A 76  ? 0.55592 0.59532 0.57678 0.01045  -0.00096 -0.03809 76  ILE A O   
563  C CB  . ILE A 76  ? 0.52605 0.58374 0.54491 0.01288  -0.02245 -0.03902 76  ILE A CB  
564  C CG1 . ILE A 76  ? 0.42995 0.49350 0.43567 0.01634  -0.03055 -0.03594 76  ILE A CG1 
565  C CG2 . ILE A 76  ? 0.46426 0.52497 0.49914 0.00821  -0.02857 -0.04708 76  ILE A CG2 
566  C CD1 . ILE A 76  ? 0.49189 0.56673 0.51342 0.01723  -0.04077 -0.03386 76  ILE A CD1 
567  N N   . HIS A 77  ? 0.46656 0.50568 0.47802 0.00866  -0.01057 -0.05083 77  HIS A N   
568  C CA  . HIS A 77  ? 0.52541 0.55658 0.54581 0.00690  -0.00414 -0.05236 77  HIS A CA  
569  C C   . HIS A 77  ? 0.56171 0.59409 0.60557 0.00322  -0.00321 -0.05109 77  HIS A C   
570  O O   . HIS A 77  ? 0.47085 0.51054 0.52719 0.00050  -0.01098 -0.05424 77  HIS A O   
571  C CB  . HIS A 77  ? 0.45394 0.47921 0.46882 0.00620  -0.00644 -0.06173 77  HIS A CB  
572  C CG  . HIS A 77  ? 0.49873 0.52210 0.49381 0.01042  -0.00369 -0.06255 77  HIS A CG  
573  N ND1 . HIS A 77  ? 0.52079 0.54886 0.49945 0.01228  -0.00856 -0.06535 77  HIS A ND1 
574  C CD2 . HIS A 77  ? 0.53278 0.55117 0.52320 0.01343  0.00376  -0.06021 77  HIS A CD2 
575  C CE1 . HIS A 77  ? 0.65027 0.67641 0.61619 0.01592  -0.00281 -0.06485 77  HIS A CE1 
576  N NE2 . HIS A 77  ? 0.59479 0.61595 0.56895 0.01672  0.00404  -0.06191 77  HIS A NE2 
577  N N   . GLY A 78  ? 0.50067 0.52648 0.55105 0.00311  0.00629  -0.04612 78  GLY A N   
578  C CA  . GLY A 78  ? 0.43755 0.46285 0.51045 -0.00049 0.01021  -0.04418 78  GLY A CA  
579  C C   . GLY A 78  ? 0.49485 0.51106 0.57621 -0.00393 0.01141  -0.04927 78  GLY A C   
580  O O   . GLY A 78  ? 0.50245 0.51255 0.57197 -0.00280 0.00902  -0.05514 78  GLY A O   
581  N N   . ASN A 79  ? 0.49510 0.50970 0.59870 -0.00804 0.01637  -0.04671 79  ASN A N   
582  C CA  . ASN A 79  ? 0.55374 0.55694 0.66739 -0.01174 0.01899  -0.05045 79  ASN A CA  
583  C C   . ASN A 79  ? 0.44158 0.43235 0.54276 -0.00716 0.02899  -0.04382 79  ASN A C   
584  O O   . ASN A 79  ? 0.59542 0.57472 0.69754 -0.00755 0.03035  -0.04734 79  ASN A O   
585  C CB  . ASN A 79  ? 0.47885 0.48423 0.62332 -0.01862 0.02170  -0.04914 79  ASN A CB  
586  C CG  . ASN A 79  ? 0.51284 0.51914 0.66478 -0.01683 0.03458  -0.03680 79  ASN A CG  
587  O OD1 . ASN A 79  ? 0.53161 0.54695 0.67879 -0.01332 0.03570  -0.03224 79  ASN A OD1 
588  N ND2 . ASN A 79  ? 0.51072 0.50643 0.67439 -0.01916 0.04513  -0.03134 79  ASN A ND2 
589  N N   . ARG A 80  ? 0.54211 0.53451 0.63075 -0.00248 0.03522  -0.03472 80  ARG A N   
590  C CA  . ARG A 80  ? 0.52920 0.51192 0.60473 0.00220  0.04251  -0.02780 80  ARG A CA  
591  C C   . ARG A 80  ? 0.57521 0.55864 0.63106 0.00704  0.03775  -0.03078 80  ARG A C   
592  O O   . ARG A 80  ? 0.53381 0.50916 0.58508 0.01047  0.04057  -0.02887 80  ARG A O   
593  C CB  . ARG A 80  ? 0.45514 0.43855 0.52397 0.00461  0.05082  -0.01749 80  ARG A CB  
594  C CG  . ARG A 80  ? 0.48081 0.46471 0.56906 0.00091  0.05855  -0.01294 80  ARG A CG  
595  C CD  . ARG A 80  ? 0.48272 0.45568 0.58671 -0.00207 0.06509  -0.00996 80  ARG A CD  
596  N NE  . ARG A 80  ? 0.65336 0.61495 0.74163 0.00298  0.07151  -0.00172 80  ARG A NE  
597  C CZ  . ARG A 80  ? 0.62760 0.57701 0.72460 0.00240  0.08009  0.00521  80  ARG A CZ  
598  N NH1 . ARG A 80  ? 0.48981 0.43619 0.61292 -0.00417 0.08428  0.00443  80  ARG A NH1 
599  N NH2 . ARG A 80  ? 0.66579 0.60608 0.74610 0.00843  0.08416  0.01370  80  ARG A NH2 
600  N N   . ASP A 81  ? 0.53573 0.52891 0.58130 0.00783  0.03137  -0.03433 81  ASP A N   
601  C CA  . ASP A 81  ? 0.47429 0.46995 0.50281 0.01209  0.02873  -0.03538 81  ASP A CA  
602  C C   . ASP A 81  ? 0.51951 0.51886 0.54417 0.01162  0.02158  -0.04505 81  ASP A C   
603  O O   . ASP A 81  ? 0.50077 0.50652 0.51248 0.01383  0.01883  -0.04571 81  ASP A O   
604  C CB  . ASP A 81  ? 0.49425 0.49612 0.51059 0.01371  0.02935  -0.02963 81  ASP A CB  
605  C CG  . ASP A 81  ? 0.54590 0.55368 0.56685 0.01115  0.02768  -0.02965 81  ASP A CG  
606  O OD1 . ASP A 81  ? 0.49237 0.50332 0.52525 0.00837  0.02359  -0.03434 81  ASP A OD1 
607  O OD2 . ASP A 81  ? 0.54524 0.55442 0.55838 0.01213  0.03011  -0.02510 81  ASP A OD2 
608  N N   . PHE A 82  ? 0.49966 0.49407 0.53455 0.00849  0.01885  -0.05282 82  PHE A N   
609  C CA  . PHE A 82  ? 0.41860 0.41511 0.44643 0.00789  0.01158  -0.06332 82  PHE A CA  
610  C C   . PHE A 82  ? 0.52647 0.51966 0.53994 0.01335  0.01401  -0.06636 82  PHE A C   
611  O O   . PHE A 82  ? 0.53541 0.53025 0.53790 0.01405  0.00968  -0.07455 82  PHE A O   
612  C CB  . PHE A 82  ? 0.41283 0.40336 0.45530 0.00221  0.00736  -0.07244 82  PHE A CB  
613  C CG  . PHE A 82  ? 0.55774 0.53336 0.61038 0.00204  0.01405  -0.07332 82  PHE A CG  
614  C CD1 . PHE A 82  ? 0.51643 0.48178 0.56139 0.00512  0.01516  -0.08145 82  PHE A CD1 
615  C CD2 . PHE A 82  ? 0.50606 0.47688 0.57563 -0.00055 0.02039  -0.06550 82  PHE A CD2 
616  C CE1 . PHE A 82  ? 0.53892 0.48873 0.59404 0.00595  0.02189  -0.08142 82  PHE A CE1 
617  C CE2 . PHE A 82  ? 0.57610 0.53173 0.65482 -0.00027 0.02714  -0.06456 82  PHE A CE2 
618  C CZ  . PHE A 82  ? 0.62675 0.57143 0.69883 0.00314  0.02758  -0.07242 82  PHE A CZ  
619  N N   . LEU A 83  ? 0.49266 0.48198 0.50577 0.01773  0.02087  -0.05971 83  LEU A N   
620  C CA  . LEU A 83  ? 0.58691 0.57580 0.59052 0.02370  0.02386  -0.06150 83  LEU A CA  
621  C C   . LEU A 83  ? 0.54989 0.55096 0.54267 0.02627  0.02405  -0.05520 83  LEU A C   
622  O O   . LEU A 83  ? 0.54473 0.54855 0.53262 0.03118  0.02732  -0.05504 83  LEU A O   
623  C CB  . LEU A 83  ? 0.51112 0.48999 0.52307 0.02802  0.03039  -0.05751 83  LEU A CB  
624  C CG  . LEU A 83  ? 0.59712 0.56005 0.61967 0.02693  0.03246  -0.06473 83  LEU A CG  
625  C CD1 . LEU A 83  ? 0.52607 0.47953 0.55548 0.03337  0.03970  -0.05795 83  LEU A CD1 
626  C CD2 . LEU A 83  ? 0.57262 0.53127 0.58778 0.02654  0.02950  -0.07940 83  LEU A CD2 
627  N N   . VAL A 84  ? 0.49493 0.50308 0.48562 0.02304  0.02128  -0.05015 84  VAL A N   
628  C CA  . VAL A 84  ? 0.54123 0.55898 0.52267 0.02421  0.02136  -0.04516 84  VAL A CA  
629  C C   . VAL A 84  ? 0.60211 0.62409 0.57300 0.02585  0.02041  -0.05079 84  VAL A C   
630  O O   . VAL A 84  ? 0.61226 0.63334 0.57842 0.02397  0.01600  -0.05687 84  VAL A O   
631  C CB  . VAL A 84  ? 0.50491 0.52619 0.48575 0.02053  0.01909  -0.04023 84  VAL A CB  
632  C CG1 . VAL A 84  ? 0.44318 0.47214 0.41511 0.02061  0.01902  -0.03626 84  VAL A CG1 
633  C CG2 . VAL A 84  ? 0.42452 0.44118 0.41193 0.01974  0.02202  -0.03439 84  VAL A CG2 
634  N N   . GLY A 85  ? 0.54061 0.56793 0.50789 0.02958  0.02458  -0.04850 85  GLY A N   
635  C CA  . GLY A 85  ? 0.47286 0.50328 0.42948 0.03226  0.02664  -0.05342 85  GLY A CA  
636  C C   . GLY A 85  ? 0.61281 0.65359 0.56264 0.03177  0.02838  -0.04746 85  GLY A C   
637  O O   . GLY A 85  ? 0.52907 0.57364 0.48148 0.02824  0.02634  -0.04073 85  GLY A O   
638  N N   . GLN A 86  ? 0.53877 0.58302 0.47965 0.03521  0.03318  -0.05011 86  GLN A N   
639  C CA  . GLN A 86  ? 0.56414 0.61738 0.49857 0.03427  0.03614  -0.04404 86  GLN A CA  
640  C C   . GLN A 86  ? 0.62442 0.68722 0.57176 0.03412  0.04029  -0.03631 86  GLN A C   
641  O O   . GLN A 86  ? 0.56119 0.63068 0.50808 0.03081  0.04141  -0.02998 86  GLN A O   
642  C CB  . GLN A 86  ? 0.51150 0.56514 0.43019 0.03825  0.04136  -0.04890 86  GLN A CB  
643  C CG  . GLN A 86  ? 0.79864 0.84641 0.70043 0.03685  0.03468  -0.05414 86  GLN A CG  
644  C CD  . GLN A 86  ? 0.89650 0.94851 0.79202 0.03338  0.03140  -0.04567 86  GLN A CD  
645  O OE1 . GLN A 86  ? 1.07735 1.13540 0.97930 0.03157  0.03560  -0.03688 86  GLN A OE1 
646  N NE2 . GLN A 86  ? 0.94344 0.99206 0.82805 0.03232  0.02331  -0.04821 86  GLN A NE2 
647  N N   . ARG A 87  ? 0.61229 0.67590 0.57206 0.03745  0.04200  -0.03633 87  ARG A N   
648  C CA  . ARG A 87  ? 0.60054 0.67487 0.57411 0.03667  0.04268  -0.02869 87  ARG A CA  
649  C C   . ARG A 87  ? 0.61707 0.69012 0.59196 0.03019  0.03572  -0.02414 87  ARG A C   
650  O O   . ARG A 87  ? 0.54221 0.62295 0.52060 0.02581  0.03498  -0.01895 87  ARG A O   
651  C CB  . ARG A 87  ? 0.49506 0.57028 0.48126 0.04292  0.04484  -0.02864 87  ARG A CB  
652  C CG  . ARG A 87  ? 0.57835 0.66564 0.57935 0.04220  0.04234  -0.02044 87  ARG A CG  
653  C CD  . ARG A 87  ? 0.73517 0.82815 0.75056 0.05056  0.04655  -0.01875 87  ARG A CD  
654  N NE  . ARG A 87  ? 0.88529 0.99093 0.91516 0.05007  0.04138  -0.01045 87  ARG A NE  
655  C CZ  . ARG A 87  ? 0.79989 0.90887 0.84270 0.05714  0.04083  -0.00635 87  ARG A CZ  
656  N NH1 . ARG A 87  ? 0.78947 0.88840 0.83404 0.06540  0.04662  -0.00988 87  ARG A NH1 
657  N NH2 . ARG A 87  ? 1.05397 1.17624 1.10822 0.05601  0.03387  0.00146  87  ARG A NH2 
658  N N   . PHE A 88  ? 0.55699 0.61971 0.52960 0.02926  0.03134  -0.02639 88  PHE A N   
659  C CA  . PHE A 88  ? 0.51876 0.57867 0.49026 0.02398  0.02659  -0.02294 88  PHE A CA  
660  C C   . PHE A 88  ? 0.55069 0.60993 0.51439 0.01962  0.02581  -0.02225 88  PHE A C   
661  O O   . PHE A 88  ? 0.43875 0.49837 0.40251 0.01508  0.02395  -0.01869 88  PHE A O   
662  C CB  . PHE A 88  ? 0.47088 0.52020 0.44247 0.02433  0.02437  -0.02486 88  PHE A CB  
663  C CG  . PHE A 88  ? 0.54830 0.59389 0.51742 0.02006  0.02157  -0.02163 88  PHE A CG  
664  C CD1 . PHE A 88  ? 0.53857 0.58587 0.50899 0.01953  0.01996  -0.01730 88  PHE A CD1 
665  C CD2 . PHE A 88  ? 0.53838 0.57901 0.50308 0.01713  0.02054  -0.02294 88  PHE A CD2 
666  C CE1 . PHE A 88  ? 0.51881 0.56099 0.48330 0.01589  0.01829  -0.01566 88  PHE A CE1 
667  C CE2 . PHE A 88  ? 0.54249 0.57845 0.50466 0.01415  0.01983  -0.02063 88  PHE A CE2 
668  C CZ  . PHE A 88  ? 0.57989 0.61574 0.54047 0.01335  0.01917  -0.01764 88  PHE A CZ  
669  N N   . ALA A 89  ? 0.49564 0.55274 0.45160 0.02114  0.02688  -0.02567 89  ALA A N   
670  C CA  . ALA A 89  ? 0.55183 0.60827 0.50000 0.01832  0.02613  -0.02319 89  ALA A CA  
671  C C   . ALA A 89  ? 0.50061 0.56431 0.45075 0.01560  0.02990  -0.01748 89  ALA A C   
672  O O   . ALA A 89  ? 0.59920 0.66047 0.54830 0.01133  0.02898  -0.01344 89  ALA A O   
673  C CB  . ALA A 89  ? 0.44773 0.50220 0.38493 0.02122  0.02570  -0.02733 89  ALA A CB  
674  N N   . ARG A 90  ? 0.59781 0.67022 0.55288 0.01796  0.03482  -0.01699 90  ARG A N   
675  C CA  . ARG A 90  ? 0.57629 0.65781 0.53753 0.01462  0.03910  -0.01113 90  ARG A CA  
676  C C   . ARG A 90  ? 0.68782 0.77199 0.66020 0.00898  0.03474  -0.00832 90  ARG A C   
677  O O   . ARG A 90  ? 0.62863 0.71296 0.60303 0.00287  0.03479  -0.00448 90  ARG A O   
678  C CB  . ARG A 90  ? 0.57514 0.66711 0.54181 0.01939  0.04660  -0.01119 90  ARG A CB  
679  N N   . GLN A 91  ? 0.50978 0.59474 0.48817 0.01080  0.03069  -0.01022 91  GLN A N   
680  C CA  . GLN A 91  ? 0.57527 0.66243 0.56009 0.00567  0.02514  -0.00822 91  GLN A CA  
681  C C   . GLN A 91  ? 0.55955 0.63453 0.53533 0.00041  0.02192  -0.00904 91  GLN A C   
682  O O   . GLN A 91  ? 0.55148 0.62661 0.52973 -0.00581 0.01861  -0.00810 91  GLN A O   
683  C CB  . GLN A 91  ? 0.57524 0.66362 0.56410 0.00987  0.02132  -0.00892 91  GLN A CB  
684  C CG  . GLN A 91  ? 0.73323 0.83423 0.73486 0.01561  0.02417  -0.00713 91  GLN A CG  
685  N N   . SER A 92  ? 0.46565 0.53015 0.43200 0.00280  0.02265  -0.01123 92  SER A N   
686  C CA  . SER A 92  ? 0.52050 0.57351 0.48047 -0.00043 0.02082  -0.01178 92  SER A CA  
687  C C   . SER A 92  ? 0.53226 0.58081 0.48827 -0.00221 0.02350  -0.00918 92  SER A C   
688  O O   . SER A 92  ? 0.52761 0.56626 0.48042 -0.00476 0.02298  -0.00889 92  SER A O   
689  C CB  . SER A 92  ? 0.50437 0.54963 0.46042 0.00349  0.01970  -0.01471 92  SER A CB  
690  O OG  . SER A 92  ? 0.43226 0.47841 0.38711 0.00777  0.02088  -0.01628 92  SER A OG  
691  N N   . GLY A 93  ? 0.49661 0.55126 0.45184 -0.00030 0.02712  -0.00677 93  GLY A N   
692  C CA  . GLY A 93  ? 0.46564 0.51547 0.41456 -0.00060 0.02963  -0.00267 93  GLY A CA  
693  C C   . GLY A 93  ? 0.48357 0.52640 0.42502 0.00380  0.02690  -0.00392 93  GLY A C   
694  O O   . GLY A 93  ? 0.58829 0.62616 0.52463 0.00432  0.02756  0.00054  93  GLY A O   
695  N N   . MET A 94  ? 0.51917 0.56193 0.46155 0.00693  0.02369  -0.00912 94  MET A N   
696  C CA  . MET A 94  ? 0.55563 0.59438 0.49533 0.01032  0.02015  -0.01080 94  MET A CA  
697  C C   . MET A 94  ? 0.60218 0.64553 0.53375 0.01414  0.01893  -0.01233 94  MET A C   
698  O O   . MET A 94  ? 0.55339 0.60192 0.48231 0.01545  0.02158  -0.01482 94  MET A O   
699  C CB  . MET A 94  ? 0.54844 0.58488 0.49459 0.01093  0.01813  -0.01543 94  MET A CB  
700  C CG  . MET A 94  ? 0.69832 0.72716 0.64803 0.00940  0.01849  -0.01431 94  MET A CG  
701  S SD  . MET A 94  ? 0.67147 0.69824 0.62866 0.01148  0.01744  -0.01808 94  MET A SD  
702  C CE  . MET A 94  ? 0.52584 0.55705 0.48368 0.01202  0.01763  -0.02131 94  MET A CE  
703  N N   . ILE A 95  ? 0.48595 0.52744 0.41316 0.01642  0.01470  -0.01109 95  ILE A N   
704  C CA  . ILE A 95  ? 0.61574 0.66083 0.53200 0.01987  0.01130  -0.01367 95  ILE A CA  
705  C C   . ILE A 95  ? 0.57799 0.62325 0.50053 0.02066  0.00511  -0.02127 95  ILE A C   
706  O O   . ILE A 95  ? 0.64176 0.68529 0.57504 0.02002  0.00185  -0.02060 95  ILE A O   
707  C CB  . ILE A 95  ? 0.50747 0.55179 0.41385 0.02202  0.00899  -0.00638 95  ILE A CB  
708  C CG1 . ILE A 95  ? 0.71436 0.75852 0.61305 0.02097  0.01683  0.00089  95  ILE A CG1 
709  C CG2 . ILE A 95  ? 0.58861 0.63654 0.48267 0.02563  0.00187  -0.01021 95  ILE A CG2 
710  C CD1 . ILE A 95  ? 0.73232 0.77109 0.62855 0.02134  0.01750  0.01132  95  ILE A CD1 
711  N N   . LEU A 96  ? 0.59607 0.64281 0.51354 0.02189  0.00456  -0.02866 96  LEU A N   
712  C CA  . LEU A 96  ? 0.61005 0.65578 0.53399 0.02156  -0.00149 -0.03663 96  LEU A CA  
713  C C   . LEU A 96  ? 0.54427 0.59295 0.45979 0.02287  -0.01066 -0.03840 96  LEU A C   
714  O O   . LEU A 96  ? 0.53957 0.58967 0.43657 0.02529  -0.01140 -0.03873 96  LEU A O   
715  C CB  . LEU A 96  ? 0.61425 0.65769 0.53659 0.02238  0.00184  -0.04465 96  LEU A CB  
716  C CG  . LEU A 96  ? 0.55886 0.60150 0.48904 0.02231  0.00969  -0.04216 96  LEU A CG  
717  C CD1 . LEU A 96  ? 0.54904 0.58870 0.47933 0.02471  0.01292  -0.04964 96  LEU A CD1 
718  C CD2 . LEU A 96  ? 0.53018 0.57047 0.47461 0.01970  0.00945  -0.03854 96  LEU A CD2 
719  N N   . LEU A 97  ? 0.61086 0.66133 0.53998 0.02148  -0.01764 -0.03916 97  LEU A N   
720  C CA  . LEU A 97  ? 0.60261 0.65846 0.52833 0.02236  -0.02897 -0.04080 97  LEU A CA  
721  C C   . LEU A 97  ? 0.52345 0.57935 0.45660 0.01929  -0.03562 -0.05242 97  LEU A C   
722  O O   . LEU A 97  ? 0.57055 0.62142 0.51523 0.01678  -0.03049 -0.05706 97  LEU A O   
723  C CB  . LEU A 97  ? 0.52108 0.58106 0.46135 0.02327  -0.03244 -0.03236 97  LEU A CB  
724  C CG  . LEU A 97  ? 0.51710 0.57406 0.45325 0.02575  -0.02577 -0.02116 97  LEU A CG  
725  C CD1 . LEU A 97  ? 0.60127 0.66062 0.55529 0.02733  -0.02827 -0.01486 97  LEU A CD1 
726  C CD2 . LEU A 97  ? 0.48309 0.54071 0.39641 0.02903  -0.02713 -0.01611 97  LEU A CD2 
727  N N   . ALA A 98  ? 0.68822 0.74946 0.61502 0.01926  -0.04774 -0.05682 98  ALA A N   
728  C CA  . ALA A 98  ? 0.60860 0.66990 0.54435 0.01487  -0.05605 -0.06886 98  ALA A CA  
729  C C   . ALA A 98  ? 0.60631 0.67245 0.57403 0.01110  -0.05850 -0.06683 98  ALA A C   
730  O O   . ALA A 98  ? 0.59755 0.66713 0.57794 0.01288  -0.05428 -0.05660 98  ALA A O   
731  C CB  . ALA A 98  ? 0.57893 0.64542 0.49676 0.01540  -0.07013 -0.07487 98  ALA A CB  
732  N N   . GLU A 99  ? 0.60885 0.67445 0.59019 0.00566  -0.06455 -0.07710 99  GLU A N   
733  C CA  . GLU A 99  ? 0.62643 0.69637 0.64050 0.00140  -0.06442 -0.07515 99  GLU A CA  
734  C C   . GLU A 99  ? 0.59747 0.68254 0.62733 0.00224  -0.07459 -0.06868 99  GLU A C   
735  O O   . GLU A 99  ? 0.46193 0.55192 0.51865 0.00120  -0.07039 -0.06270 99  GLU A O   
736  C CB  . GLU A 99  ? 0.53732 0.60181 0.56417 -0.00560 -0.06767 -0.08754 99  GLU A CB  
737  C CG  . GLU A 99  ? 0.72647 0.79740 0.75115 -0.00973 -0.08488 -0.09835 99  GLU A CG  
738  C CD  . GLU A 99  ? 0.85814 0.92150 0.89895 -0.01811 -0.08755 -0.11136 99  GLU A CD  
739  O OE1 . GLU A 99  ? 0.93284 1.00602 1.00025 -0.02459 -0.09752 -0.11411 99  GLU A OE1 
740  O OE2 . GLU A 99  ? 1.02135 1.06900 1.05057 -0.01827 -0.07946 -0.11854 99  GLU A OE2 
741  N N   . GLU A 100 ? 0.54205 0.63470 0.55565 0.00489  -0.08719 -0.06895 100 GLU A N   
742  C CA  . GLU A 100 ? 0.55814 0.66554 0.58365 0.00818  -0.09692 -0.06005 100 GLU A CA  
743  C C   . GLU A 100 ? 0.59953 0.70596 0.59680 0.01580  -0.09684 -0.05109 100 GLU A C   
744  O O   . GLU A 100 ? 0.70960 0.81105 0.67658 0.01695  -0.09979 -0.05599 100 GLU A O   
745  C CB  . GLU A 100 ? 0.60300 0.72325 0.63957 0.00354  -0.11631 -0.06826 100 GLU A CB  
746  C CG  . GLU A 100 ? 0.76315 0.88961 0.83882 -0.00400 -0.11756 -0.07270 100 GLU A CG  
747  C CD  . GLU A 100 ? 0.81693 0.95342 0.90138 -0.01121 -0.13733 -0.08479 100 GLU A CD  
748  O OE1 . GLU A 100 ? 0.76418 0.90871 0.82925 -0.00866 -0.15319 -0.08627 100 GLU A OE1 
749  O OE2 . GLU A 100 ? 0.69155 0.82743 0.80204 -0.01980 -0.13724 -0.09272 100 GLU A OE2 
750  N N   . GLU A 101 ? 0.53694 0.64682 0.54386 0.02117  -0.09223 -0.03790 101 GLU A N   
751  C CA  . GLU A 101 ? 0.50225 0.61060 0.48657 0.02825  -0.09198 -0.02743 101 GLU A CA  
752  C C   . GLU A 101 ? 0.50506 0.62490 0.50858 0.03367  -0.09875 -0.01588 101 GLU A C   
753  O O   . GLU A 101 ? 0.71966 0.84514 0.75470 0.03296  -0.09602 -0.01378 101 GLU A O   
754  C CB  . GLU A 101 ? 0.57239 0.66693 0.54489 0.03003  -0.07454 -0.02191 101 GLU A CB  
755  C CG  . GLU A 101 ? 0.70767 0.79227 0.65980 0.02681  -0.06742 -0.03073 101 GLU A CG  
756  C CD  . GLU A 101 ? 0.72324 0.80638 0.64230 0.02966  -0.07127 -0.03133 101 GLU A CD  
757  O OE1 . GLU A 101 ? 1.05886 1.14911 0.96829 0.03346  -0.08227 -0.02619 101 GLU A OE1 
758  O OE2 . GLU A 101 ? 1.04627 1.12151 0.94877 0.02860  -0.06299 -0.03667 101 GLU A OE2 
759  N N   . ARG A 102 ? 0.62798 0.75106 0.61242 0.03988  -0.10661 -0.00752 102 ARG A N   
760  C CA  . ARG A 102 ? 0.61081 0.74358 0.61095 0.04716  -0.11282 0.00578  102 ARG A CA  
761  C C   . ARG A 102 ? 0.59307 0.71337 0.57684 0.05368  -0.10123 0.01878  102 ARG A C   
762  O O   . ARG A 102 ? 0.65553 0.76767 0.60743 0.05459  -0.09897 0.02022  102 ARG A O   
763  C CB  . ARG A 102 ? 0.67732 0.82590 0.67134 0.04952  -0.13477 0.00628  102 ARG A CB  
764  C CG  . ARG A 102 ? 0.88419 1.04339 0.89174 0.05901  -0.14248 0.02229  102 ARG A CG  
765  C CD  . ARG A 102 ? 0.76303 0.93821 0.75895 0.06170  -0.16604 0.02336  102 ARG A CD  
766  N NE  . ARG A 102 ? 0.98983 1.16851 0.97406 0.05267  -0.17680 0.00571  102 ARG A NE  
767  C CZ  . ARG A 102 ? 1.19866 1.37078 1.14157 0.05171  -0.18199 -0.00062 102 ARG A CZ  
768  N NH1 . ARG A 102 ? 1.04221 1.20535 0.95130 0.05899  -0.17734 0.01039  102 ARG A NH1 
769  N NH2 . ARG A 102 ? 1.14116 1.31444 1.07649 0.04323  -0.19073 -0.01853 102 ARG A NH2 
770  N N   . LEU A 103 ? 0.63700 0.75480 0.64309 0.05789  -0.09269 0.02780  103 LEU A N   
771  C CA  . LEU A 103 ? 0.71283 0.81610 0.70827 0.06283  -0.08035 0.03898  103 LEU A CA  
772  C C   . LEU A 103 ? 0.61202 0.72074 0.61936 0.07269  -0.08630 0.05379  103 LEU A C   
773  O O   . LEU A 103 ? 0.71112 0.83537 0.74463 0.07573  -0.09625 0.05533  103 LEU A O   
774  C CB  . LEU A 103 ? 0.53290 0.62346 0.54108 0.05957  -0.06287 0.03599  103 LEU A CB  
775  C CG  . LEU A 103 ? 0.67900 0.76604 0.68564 0.05091  -0.05666 0.02261  103 LEU A CG  
776  C CD1 . LEU A 103 ? 0.53502 0.61264 0.55799 0.04966  -0.04219 0.02192  103 LEU A CD1 
777  C CD2 . LEU A 103 ? 0.56310 0.64139 0.53910 0.04754  -0.05289 0.01927  103 LEU A CD2 
778  N N   . ASP A 104 ? 0.67861 0.77457 0.66873 0.07780  -0.07970 0.06544  104 ASP A N   
779  C CA  . ASP A 104 ? 0.65259 0.74770 0.65540 0.08809  -0.08054 0.08113  104 ASP A CA  
780  C C   . ASP A 104 ? 0.71691 0.79437 0.73325 0.08825  -0.06186 0.08268  104 ASP A C   
781  O O   . ASP A 104 ? 0.75575 0.81550 0.75421 0.08538  -0.05003 0.08405  104 ASP A O   
782  C CB  . ASP A 104 ? 0.84415 0.93482 0.81870 0.09413  -0.08550 0.09448  104 ASP A CB  
783  C CG  . ASP A 104 ? 0.88333 0.97189 0.87207 0.10597  -0.08651 0.11238  104 ASP A CG  
784  O OD1 . ASP A 104 ? 0.83005 0.93571 0.84317 0.11209  -0.09868 0.11604  104 ASP A OD1 
785  O OD2 . ASP A 104 ? 1.04991 1.11972 1.02774 0.10915  -0.07486 0.12305  104 ASP A OD2 
786  N N   . LEU A 105 ? 0.61231 0.69480 0.66052 0.09130  -0.05902 0.08194  105 LEU A N   
787  C CA  . LEU A 105 ? 0.67455 0.73975 0.73497 0.09234  -0.04146 0.08217  105 LEU A CA  
788  C C   . LEU A 105 ? 0.55650 0.61842 0.63259 0.10464  -0.04074 0.09723  105 LEU A C   
789  O O   . LEU A 105 ? 0.50300 0.57772 0.60864 0.11129  -0.04413 0.10035  105 LEU A O   
790  C CB  . LEU A 105 ? 0.55523 0.62577 0.63761 0.08762  -0.03539 0.07053  105 LEU A CB  
791  C CG  . LEU A 105 ? 0.63278 0.70436 0.70092 0.07633  -0.03505 0.05677  105 LEU A CG  
792  C CD1 . LEU A 105 ? 0.53560 0.61065 0.62530 0.07250  -0.02763 0.04773  105 LEU A CD1 
793  C CD2 . LEU A 105 ? 0.62045 0.67300 0.66098 0.07119  -0.02541 0.05484  105 LEU A CD2 
794  N N   . TYR A 106 ? 0.59798 0.64271 0.65566 0.10787  -0.03579 0.10738  106 TYR A N   
795  C CA  . TYR A 106 ? 0.67476 0.71034 0.74454 0.11981  -0.03254 0.12275  106 TYR A CA  
796  C C   . TYR A 106 ? 0.60952 0.66785 0.69623 0.13028  -0.04953 0.13361  106 TYR A C   
797  O O   . TYR A 106 ? 0.66610 0.72584 0.77952 0.14111  -0.04766 0.14267  106 TYR A O   
798  C CB  . TYR A 106 ? 0.57016 0.59001 0.66106 0.12205  -0.01560 0.11898  106 TYR A CB  
799  C CG  . TYR A 106 ? 0.58691 0.58963 0.66264 0.11025  -0.00230 0.10518  106 TYR A CG  
800  C CD1 . TYR A 106 ? 0.53571 0.51585 0.58989 0.10578  0.00636  0.10729  106 TYR A CD1 
801  C CD2 . TYR A 106 ? 0.50816 0.51832 0.59162 0.10327  0.00085  0.09081  106 TYR A CD2 
802  C CE1 . TYR A 106 ? 0.63738 0.60455 0.67938 0.09469  0.01635  0.09473  106 TYR A CE1 
803  C CE2 . TYR A 106 ? 0.63050 0.62644 0.69923 0.09319  0.01128  0.07918  106 TYR A CE2 
804  C CZ  . TYR A 106 ? 0.65205 0.62759 0.70048 0.08891  0.01810  0.08084  106 TYR A CZ  
805  O OH  . TYR A 106 ? 0.60578 0.56987 0.64162 0.07873  0.02644  0.06932  106 TYR A OH  
806  N N   . GLY A 107 ? 0.72095 0.79760 0.79263 0.12730  -0.06655 0.13223  107 GLY A N   
807  C CA  . GLY A 107 ? 0.74267 0.84211 0.82503 0.13607  -0.08615 0.14225  107 GLY A CA  
808  C C   . GLY A 107 ? 0.77117 0.89754 0.87660 0.13193  -0.09933 0.13134  107 GLY A C   
809  O O   . GLY A 107 ? 0.89577 1.04369 1.00295 0.13546  -0.11975 0.13589  107 GLY A O   
810  N N   . ARG A 108 ? 0.65938 0.78525 0.78258 0.12436  -0.08882 0.11749  108 ARG A N   
811  C CA  . ARG A 108 ? 0.72064 0.87065 0.86819 0.11912  -0.09953 0.10729  108 ARG A CA  
812  C C   . ARG A 108 ? 0.63312 0.78308 0.75531 0.10586  -0.10353 0.09183  108 ARG A C   
813  O O   . ARG A 108 ? 0.60605 0.73685 0.70721 0.09915  -0.08959 0.08458  108 ARG A O   
814  C CB  . ARG A 108 ? 0.83601 0.98716 1.02096 0.11984  -0.08526 0.10312  108 ARG A CB  
815  C CG  . ARG A 108 ? 0.93208 1.05825 1.10569 0.11416  -0.06294 0.09479  108 ARG A CG  
816  C CD  . ARG A 108 ? 0.73053 0.86202 0.93361 0.11063  -0.05182 0.08578  108 ARG A CD  
817  N NE  . ARG A 108 ? 0.76493 0.89623 0.99959 0.12177  -0.04122 0.09406  108 ARG A NE  
818  C CZ  . ARG A 108 ? 0.92274 1.03024 1.15158 0.12795  -0.02450 0.09822  108 ARG A CZ  
819  N NH1 . ARG A 108 ? 0.74440 0.82736 0.93858 0.12377  -0.01767 0.09621  108 ARG A NH1 
820  N NH2 . ARG A 108 ? 0.77127 0.87959 1.03122 0.13860  -0.01422 0.10436  108 ARG A NH2 
821  N N   . GLU A 109 ? 0.58873 0.75997 0.71281 0.10247  -0.12332 0.08693  109 GLU A N   
822  C CA  . GLU A 109 ? 0.70303 0.87472 0.80570 0.09062  -0.12830 0.07138  109 GLU A CA  
823  C C   . GLU A 109 ? 0.55605 0.73077 0.68523 0.08201  -0.11973 0.05852  109 GLU A C   
824  O O   . GLU A 109 ? 0.67596 0.86872 0.84269 0.08280  -0.12502 0.05870  109 GLU A O   
825  C CB  . GLU A 109 ? 0.64479 0.83606 0.73792 0.09019  -0.15330 0.07005  109 GLU A CB  
826  N N   . VAL A 110 ? 0.57058 0.72836 0.68184 0.07417  -0.10608 0.04855  110 VAL A N   
827  C CA  . VAL A 110 ? 0.57761 0.73443 0.70919 0.06661  -0.09557 0.03807  110 VAL A CA  
828  C C   . VAL A 110 ? 0.64810 0.80215 0.75974 0.05618  -0.09959 0.02397  110 VAL A C   
829  O O   . VAL A 110 ? 0.56533 0.70682 0.64254 0.05473  -0.09761 0.02179  110 VAL A O   
830  C CB  . VAL A 110 ? 0.59906 0.73609 0.73005 0.06805  -0.07326 0.04000  110 VAL A CB  
831  C CG1 . VAL A 110 ? 0.52002 0.65838 0.67423 0.06201  -0.06292 0.03170  110 VAL A CG1 
832  C CG2 . VAL A 110 ? 0.53748 0.67119 0.68046 0.07929  -0.06793 0.05365  110 VAL A CG2 
833  N N   . LEU A 111 ? 0.53724 0.70237 0.67209 0.04906  -0.10401 0.01472  111 LEU A N   
834  C CA  . LEU A 111 ? 0.57385 0.73327 0.69470 0.03916  -0.10478 0.00071  111 LEU A CA  
835  C C   . LEU A 111 ? 0.48499 0.63048 0.61161 0.03514  -0.08518 -0.00306 111 LEU A C   
836  O O   . LEU A 111 ? 0.60770 0.75687 0.76333 0.03609  -0.07625 0.00036  111 LEU A O   
837  C CB  . LEU A 111 ? 0.58567 0.76320 0.72782 0.03264  -0.12170 -0.00772 111 LEU A CB  
838  C CG  . LEU A 111 ? 0.49211 0.66372 0.63509 0.02172  -0.11954 -0.02230 111 LEU A CG  
839  C CD1 . LEU A 111 ? 0.53410 0.69496 0.63693 0.01893  -0.12546 -0.03166 111 LEU A CD1 
840  C CD2 . LEU A 111 ? 0.63641 0.82766 0.81590 0.01532  -0.13312 -0.02762 111 LEU A CD2 
841  N N   . ILE A 112 ? 0.44153 0.57161 0.54040 0.03133  -0.07818 -0.00945 112 ILE A N   
842  C CA  . ILE A 112 ? 0.54774 0.66486 0.64842 0.02774  -0.06153 -0.01270 112 ILE A CA  
843  C C   . ILE A 112 ? 0.52513 0.63852 0.61974 0.01970  -0.06351 -0.02470 112 ILE A C   
844  O O   . ILE A 112 ? 0.49685 0.61005 0.57124 0.01791  -0.07335 -0.03104 112 ILE A O   
845  C CB  . ILE A 112 ? 0.50064 0.60162 0.57754 0.03140  -0.04898 -0.00766 112 ILE A CB  
846  C CG1 . ILE A 112 ? 0.47051 0.56519 0.51451 0.03077  -0.05307 -0.01047 112 ILE A CG1 
847  C CG2 . ILE A 112 ? 0.39860 0.50005 0.48360 0.03931  -0.04571 0.00372  112 ILE A CG2 
848  C CD1 . ILE A 112 ? 0.40621 0.48595 0.43134 0.03144  -0.04004 -0.00774 112 ILE A CD1 
849  N N   . MET A 113 ? 0.46596 0.57508 0.57724 0.01542  -0.05322 -0.02749 113 MET A N   
850  C CA  . MET A 113 ? 0.45504 0.55751 0.56365 0.00836  -0.05225 -0.03751 113 MET A CA  
851  C C   . MET A 113 ? 0.49094 0.58543 0.61293 0.00661  -0.03634 -0.03522 113 MET A C   
852  O O   . MET A 113 ? 0.46235 0.55870 0.59784 0.01015  -0.02769 -0.02756 113 MET A O   
853  C CB  . MET A 113 ? 0.36825 0.48232 0.49435 0.00232  -0.06698 -0.04559 113 MET A CB  
854  C CG  . MET A 113 ? 0.41381 0.54127 0.58017 -0.00000 -0.06686 -0.04201 113 MET A CG  
855  S SD  . MET A 113 ? 0.69300 0.83568 0.88414 -0.00920 -0.08611 -0.05247 113 MET A SD  
856  C CE  . MET A 113 ? 0.46044 0.61770 0.63729 -0.00345 -0.10642 -0.05016 113 MET A CE  
857  N N   . HIS A 114 ? 0.47206 0.55661 0.58894 0.00179  -0.03194 -0.04166 114 HIS A N   
858  C CA  . HIS A 114 ? 0.43576 0.51238 0.56340 0.00029  -0.01739 -0.03851 114 HIS A CA  
859  C C   . HIS A 114 ? 0.49436 0.58094 0.65785 -0.00348 -0.01607 -0.03683 114 HIS A C   
860  O O   . HIS A 114 ? 0.42808 0.51317 0.60376 -0.00179 -0.00308 -0.03002 114 HIS A O   
861  C CB  . HIS A 114 ? 0.40550 0.46890 0.52034 -0.00297 -0.01332 -0.04426 114 HIS A CB  
862  C CG  . HIS A 114 ? 0.46094 0.51550 0.58348 -0.00379 0.00108  -0.03950 114 HIS A CG  
863  N ND1 . HIS A 114 ? 0.51223 0.56168 0.62483 0.00079  0.01210  -0.03194 114 HIS A ND1 
864  C CD2 . HIS A 114 ? 0.42904 0.47828 0.56743 -0.00867 0.00636  -0.04079 114 HIS A CD2 
865  C CE1 . HIS A 114 ? 0.43341 0.47537 0.55257 -0.00065 0.02321  -0.02855 114 HIS A CE1 
866  N NE2 . HIS A 114 ? 0.45157 0.49322 0.58744 -0.00622 0.02058  -0.03290 114 HIS A NE2 
867  N N   . GLY A 115 ? 0.45790 0.55483 0.63868 -0.00891 -0.02912 -0.04326 115 GLY A N   
868  C CA  . GLY A 115 ? 0.41054 0.52005 0.63016 -0.01373 -0.02966 -0.04197 115 GLY A CA  
869  C C   . GLY A 115 ? 0.52414 0.62768 0.75977 -0.02299 -0.02798 -0.04856 115 GLY A C   
870  O O   . GLY A 115 ? 0.48292 0.59820 0.75389 -0.02898 -0.03047 -0.04879 115 GLY A O   
871  N N   . ASP A 116 ? 0.56540 0.65133 0.77908 -0.02446 -0.02368 -0.05355 116 ASP A N   
872  C CA  . ASP A 116 ? 0.48476 0.56261 0.71614 -0.03285 -0.02040 -0.05855 116 ASP A CA  
873  C C   . ASP A 116 ? 0.55922 0.64425 0.80442 -0.04116 -0.03802 -0.07084 116 ASP A C   
874  O O   . ASP A 116 ? 0.58375 0.66897 0.85817 -0.05012 -0.03777 -0.07426 116 ASP A O   
875  C CB  . ASP A 116 ? 0.57065 0.62722 0.77704 -0.03105 -0.01070 -0.05962 116 ASP A CB  
876  C CG  . ASP A 116 ? 0.62250 0.67260 0.79700 -0.02816 -0.01993 -0.06826 116 ASP A CG  
877  O OD1 . ASP A 116 ? 0.60119 0.65922 0.75842 -0.02282 -0.02644 -0.06710 116 ASP A OD1 
878  O OD2 . ASP A 116 ? 0.62347 0.65974 0.79080 -0.03090 -0.01954 -0.07578 116 ASP A OD2 
879  N N   . THR A 117 ? 0.52413 0.61520 0.74912 -0.03878 -0.05351 -0.07739 117 THR A N   
880  C CA  . THR A 117 ? 0.41550 0.51309 0.64836 -0.04655 -0.07217 -0.09043 117 THR A CA  
881  C C   . THR A 117 ? 0.56153 0.68253 0.83310 -0.05136 -0.08267 -0.08821 117 THR A C   
882  O O   . THR A 117 ? 0.52344 0.65244 0.80602 -0.05917 -0.10014 -0.09923 117 THR A O   
883  C CB  . THR A 117 ? 0.52149 0.61860 0.71717 -0.04165 -0.08504 -0.09713 117 THR A CB  
884  O OG1 . THR A 117 ? 0.60467 0.71137 0.78835 -0.03212 -0.08384 -0.08577 117 THR A OG1 
885  C CG2 . THR A 117 ? 0.59393 0.66902 0.75701 -0.03903 -0.07676 -0.10288 117 THR A CG2 
886  N N   . LEU A 118 ? 0.51373 0.64640 0.80576 -0.04655 -0.07305 -0.07477 118 LEU A N   
887  C CA  . LEU A 118 ? 0.59674 0.75332 0.93170 -0.05013 -0.08011 -0.07077 118 LEU A CA  
888  C C   . LEU A 118 ? 0.47903 0.63593 0.85452 -0.05984 -0.06996 -0.06994 118 LEU A C   
889  O O   . LEU A 118 ? 0.51995 0.69806 0.93758 -0.06467 -0.07538 -0.06735 118 LEU A O   
890  C CB  . LEU A 118 ? 0.63284 0.80110 0.97163 -0.03910 -0.07284 -0.05662 118 LEU A CB  
891  C CG  . LEU A 118 ? 0.61866 0.78569 0.91974 -0.02930 -0.08085 -0.05500 118 LEU A CG  
892  C CD1 . LEU A 118 ? 0.35704 0.52766 0.65880 -0.01822 -0.06852 -0.04107 118 LEU A CD1 
893  C CD2 . LEU A 118 ? 0.43536 0.61992 0.74029 -0.03174 -0.10605 -0.06145 118 LEU A CD2 
894  N N   . CYS A 119 ? 0.49520 0.62977 0.86038 -0.06258 -0.05533 -0.07116 119 CYS A N   
895  C CA  . CYS A 119 ? 0.65516 0.78603 1.05464 -0.07019 -0.04073 -0.06683 119 CYS A CA  
896  C C   . CYS A 119 ? 0.70502 0.82954 1.12126 -0.08392 -0.05110 -0.08044 119 CYS A C   
897  O O   . CYS A 119 ? 0.74111 0.84429 1.15421 -0.08841 -0.04036 -0.08261 119 CYS A O   
898  C CB  . CYS A 119 ? 0.53203 0.64149 0.90930 -0.06397 -0.01800 -0.05792 119 CYS A CB  
899  S SG  . CYS A 119 ? 0.61931 0.73510 0.98501 -0.05019 -0.00278 -0.04230 119 CYS A SG  
900  N N   . THR A 120 ? 0.47995 0.62309 0.91451 -0.09053 -0.07294 -0.08965 120 THR A N   
901  C CA  . THR A 120 ? 0.71863 0.85600 1.16237 -0.10372 -0.08823 -0.10649 120 THR A CA  
902  C C   . THR A 120 ? 0.62770 0.76548 1.12057 -0.11736 -0.08100 -0.10626 120 THR A C   
903  O O   . THR A 120 ? 0.67447 0.80669 1.18010 -0.13011 -0.09357 -0.12099 120 THR A O   
904  C CB  . THR A 120 ? 0.59845 0.75718 1.04271 -0.10607 -0.11606 -0.11638 120 THR A CB  
905  O OG1 . THR A 120 ? 0.53493 0.72407 1.02410 -0.10761 -0.12074 -0.10731 120 THR A OG1 
906  C CG2 . THR A 120 ? 0.55950 0.71583 0.95358 -0.09285 -0.12222 -0.11584 120 THR A CG2 
907  N N   . ASP A 121 ? 0.70133 0.84429 1.22129 -0.11539 -0.06053 -0.09040 121 ASP A N   
908  C CA  . ASP A 121 ? 0.59733 0.73728 1.16171 -0.12773 -0.04890 -0.08763 121 ASP A CA  
909  C C   . ASP A 121 ? 0.75416 0.86167 1.30009 -0.12694 -0.02760 -0.08357 121 ASP A C   
910  O O   . ASP A 121 ? 0.73382 0.83181 1.31073 -0.13840 -0.01935 -0.08370 121 ASP A O   
911  C CB  . ASP A 121 ? 0.50297 0.66778 1.11034 -0.12615 -0.03676 -0.07169 121 ASP A CB  
912  C CG  . ASP A 121 ? 0.69721 0.89636 1.33173 -0.12721 -0.05794 -0.07419 121 ASP A CG  
913  O OD1 . ASP A 121 ? 0.64114 0.84846 1.29066 -0.13872 -0.08093 -0.08869 121 ASP A OD1 
914  O OD2 . ASP A 121 ? 0.70606 0.92308 1.34483 -0.11602 -0.05242 -0.06212 121 ASP A OD2 
915  N N   . ASP A 122 ? 0.59758 0.68841 1.09572 -0.11390 -0.01890 -0.07933 122 ASP A N   
916  C CA  . ASP A 122 ? 0.65402 0.71626 1.13308 -0.11087 0.00083  -0.07311 122 ASP A CA  
917  C C   . ASP A 122 ? 0.74452 0.78282 1.20055 -0.11482 -0.00827 -0.08866 122 ASP A C   
918  O O   . ASP A 122 ? 0.67742 0.69921 1.09190 -0.10525 -0.00545 -0.08972 122 ASP A O   
919  C CB  . ASP A 122 ? 0.67475 0.73309 1.11698 -0.09520 0.01403  -0.06060 122 ASP A CB  
920  C CG  . ASP A 122 ? 0.94469 0.97928 1.37455 -0.09154 0.03623  -0.04944 122 ASP A CG  
921  O OD1 . ASP A 122 ? 0.79853 0.81552 1.24198 -0.09978 0.04083  -0.05220 122 ASP A OD1 
922  O OD2 . ASP A 122 ? 0.97859 1.01112 1.38342 -0.08020 0.04831  -0.03813 122 ASP A OD2 
923  N N   . GLN A 123 ? 0.69205 0.81128 1.09886 -0.01719 -0.04341 -0.19472 123 GLN A N   
924  C CA  . GLN A 123 ? 0.71605 0.82181 1.10463 -0.01640 -0.05797 -0.19688 123 GLN A CA  
925  C C   . GLN A 123 ? 0.64254 0.71764 0.99951 -0.02592 -0.04718 -0.18558 123 GLN A C   
926  O O   . GLN A 123 ? 0.68727 0.74712 1.01809 -0.02068 -0.05772 -0.18395 123 GLN A O   
927  C CB  . GLN A 123 ? 0.77006 0.89489 1.19776 -0.02391 -0.06930 -0.21427 123 GLN A CB  
928  C CG  . GLN A 123 ? 0.77639 0.93487 1.23751 -0.01258 -0.08318 -0.22746 123 GLN A CG  
929  C CD  . GLN A 123 ? 1.05187 1.23418 1.56285 -0.02345 -0.09143 -0.24676 123 GLN A CD  
930  O OE1 . GLN A 123 ? 0.98229 1.19014 1.53714 -0.03024 -0.08359 -0.25415 123 GLN A OE1 
931  N NE2 . GLN A 123 ? 1.04177 1.21658 1.54871 -0.02539 -0.10699 -0.25624 123 GLN A NE2 
932  N N   . GLY A 124 ? 0.64711 0.71328 1.00412 -0.03807 -0.02661 -0.17780 124 GLY A N   
933  C CA  . GLY A 124 ? 0.64200 0.67891 0.96357 -0.04267 -0.01780 -0.16559 124 GLY A CA  
934  C C   . GLY A 124 ? 0.76305 0.78817 1.04870 -0.02918 -0.02131 -0.15630 124 GLY A C   
935  O O   . GLY A 124 ? 0.62344 0.62928 0.88053 -0.02682 -0.02522 -0.15045 124 GLY A O   
936  N N   . TYR A 125 ? 0.67912 0.71576 0.96842 -0.02011 -0.01979 -0.15535 125 TYR A N   
937  C CA  . TYR A 125 ? 0.67463 0.69917 0.93472 -0.00878 -0.02226 -0.14665 125 TYR A CA  
938  C C   . TYR A 125 ? 0.65968 0.68312 0.90689 0.00295  -0.03928 -0.14704 125 TYR A C   
939  O O   . TYR A 125 ? 0.58004 0.58751 0.79932 0.00736  -0.04069 -0.13905 125 TYR A O   
940  C CB  . TYR A 125 ? 0.55305 0.58706 0.82168 -0.00164 -0.01668 -0.14611 125 TYR A CB  
941  C CG  . TYR A 125 ? 0.68728 0.70873 0.93169 0.00998  -0.02127 -0.13800 125 TYR A CG  
942  C CD1 . TYR A 125 ? 0.63959 0.64118 0.85748 0.00706  -0.01561 -0.12994 125 TYR A CD1 
943  C CD2 . TYR A 125 ? 0.52265 0.55180 0.77208 0.02389  -0.03091 -0.13803 125 TYR A CD2 
944  C CE1 . TYR A 125 ? 0.62591 0.61690 0.82690 0.01557  -0.01853 -0.12286 125 TYR A CE1 
945  C CE2 . TYR A 125 ? 0.53995 0.55511 0.76889 0.03303  -0.03269 -0.12875 125 TYR A CE2 
946  C CZ  . TYR A 125 ? 0.61102 0.60786 0.81797 0.02768  -0.02592 -0.12161 125 TYR A CZ  
947  O OH  . TYR A 125 ? 0.61379 0.59806 0.80591 0.03468  -0.02643 -0.11295 125 TYR A OH  
948  N N   . LEU A 126 ? 0.59532 0.63700 0.86244 0.00892  -0.05227 -0.15672 126 LEU A N   
949  C CA  . LEU A 126 ? 0.65012 0.69159 0.90049 0.02284  -0.06842 -0.15698 126 LEU A CA  
950  C C   . LEU A 126 ? 0.55886 0.58479 0.78801 0.01941  -0.07212 -0.15647 126 LEU A C   
951  O O   . LEU A 126 ? 0.61382 0.63031 0.81554 0.02962  -0.07696 -0.14995 126 LEU A O   
952  C CB  . LEU A 126 ? 0.62125 0.68651 0.89605 0.03103  -0.08403 -0.16973 126 LEU A CB  
953  C CG  . LEU A 126 ? 0.82891 0.91277 1.12497 0.04044  -0.08574 -0.17188 126 LEU A CG  
954  C CD1 . LEU A 126 ? 0.64745 0.71909 0.91669 0.05529  -0.08517 -0.15825 126 LEU A CD1 
955  C CD2 . LEU A 126 ? 0.78206 0.87603 1.10795 0.02854  -0.07077 -0.17519 126 LEU A CD2 
956  N N   . ALA A 127 ? 0.52772 0.54992 0.76966 0.00539  -0.06871 -0.16274 127 ALA A N   
957  C CA  . ALA A 127 ? 0.57326 0.57800 0.79553 0.00281  -0.07195 -0.16265 127 ALA A CA  
958  C C   . ALA A 127 ? 0.65535 0.64035 0.84797 0.00314  -0.06159 -0.14883 127 ALA A C   
959  O O   . ALA A 127 ? 0.61057 0.58604 0.77915 0.01082  -0.06671 -0.14563 127 ALA A O   
960  C CB  . ALA A 127 ? 0.55829 0.55910 0.80228 -0.01303 -0.06891 -0.17080 127 ALA A CB  
961  N N   . PHE A 128 ? 0.56003 0.54038 0.75470 -0.00443 -0.04723 -0.14172 128 PHE A N   
962  C CA  . PHE A 128 ? 0.57381 0.53866 0.74338 -0.00317 -0.03942 -0.13072 128 PHE A CA  
963  C C   . PHE A 128 ? 0.63808 0.60507 0.79311 0.00996  -0.04415 -0.12504 128 PHE A C   
964  O O   . PHE A 128 ? 0.65560 0.61234 0.79000 0.01411  -0.04465 -0.11931 128 PHE A O   
965  C CB  . PHE A 128 ? 0.58539 0.54817 0.75982 -0.01111 -0.02503 -0.12658 128 PHE A CB  
966  C CG  . PHE A 128 ? 0.85268 0.80221 1.00416 -0.00925 -0.01896 -0.11797 128 PHE A CG  
967  C CD1 . PHE A 128 ? 0.77103 0.70454 0.90638 -0.01453 -0.01452 -0.11400 128 PHE A CD1 
968  C CD2 . PHE A 128 ? 0.68097 0.63370 0.82903 -0.00209 -0.01812 -0.11449 128 PHE A CD2 
969  C CE1 . PHE A 128 ? 0.86253 0.78676 0.97908 -0.01191 -0.01113 -0.10817 128 PHE A CE1 
970  C CE2 . PHE A 128 ? 0.74727 0.68957 0.87910 -0.00136 -0.01381 -0.10908 128 PHE A CE2 
971  C CZ  . PHE A 128 ? 0.69350 0.62322 0.80983 -0.00596 -0.01106 -0.10665 128 PHE A CZ  
972  N N   . ARG A 129 ? 0.63101 0.61124 0.79784 0.01709  -0.04725 -0.12613 129 ARG A N   
973  C CA  . ARG A 129 ? 0.63938 0.61840 0.79287 0.02923  -0.04943 -0.11816 129 ARG A CA  
974  C C   . ARG A 129 ? 0.70387 0.68137 0.83890 0.03899  -0.05896 -0.11718 129 ARG A C   
975  O O   . ARG A 129 ? 0.59929 0.56838 0.71576 0.04408  -0.05574 -0.10815 129 ARG A O   
976  C CB  . ARG A 129 ? 0.55027 0.54192 0.72003 0.03667  -0.05196 -0.11944 129 ARG A CB  
977  C CG  . ARG A 129 ? 0.66303 0.64917 0.81961 0.04890  -0.05218 -0.10879 129 ARG A CG  
978  C CD  . ARG A 129 ? 0.63765 0.63473 0.80839 0.05952  -0.05750 -0.10997 129 ARG A CD  
979  N NE  . ARG A 129 ? 0.58760 0.57403 0.74830 0.06890  -0.05388 -0.09781 129 ARG A NE  
980  C CZ  . ARG A 129 ? 0.64950 0.62961 0.78985 0.08013  -0.05729 -0.08780 129 ARG A CZ  
981  N NH1 . ARG A 129 ? 0.62726 0.61198 0.75236 0.08531  -0.06569 -0.08985 129 ARG A NH1 
982  N NH2 . ARG A 129 ? 0.73977 0.70779 0.87484 0.08660  -0.05134 -0.07546 129 ARG A NH2 
983  N N   . ALA A 130 ? 0.48517 0.47207 0.62626 0.04207  -0.07058 -0.12744 130 ALA A N   
984  C CA  . ALA A 130 ? 0.68035 0.66679 0.80127 0.05325  -0.08051 -0.12890 130 ALA A CA  
985  C C   . ALA A 130 ? 0.74260 0.71480 0.84551 0.04952  -0.07573 -0.12584 130 ALA A C   
986  O O   . ALA A 130 ? 0.64058 0.61004 0.72175 0.05983  -0.07720 -0.12107 130 ALA A O   
987  C CB  . ALA A 130 ? 0.53911 0.53799 0.67268 0.05557  -0.09540 -0.14459 130 ALA A CB  
988  N N   . LYS A 131 ? 0.68583 0.64915 0.79687 0.03602  -0.06942 -0.12799 131 LYS A N   
989  C CA  . LYS A 131 ? 0.63881 0.58818 0.73411 0.03358  -0.06580 -0.12533 131 LYS A CA  
990  C C   . LYS A 131 ? 0.67723 0.62241 0.75882 0.03747  -0.05723 -0.11306 131 LYS A C   
991  O O   . LYS A 131 ? 0.65205 0.59629 0.71718 0.04625  -0.05805 -0.10954 131 LYS A O   
992  C CB  . LYS A 131 ? 0.82823 0.76738 0.93419 0.01935  -0.06021 -0.12800 131 LYS A CB  
993  C CG  . LYS A 131 ? 0.99222 0.91545 1.08499 0.01751  -0.06029 -0.12863 131 LYS A CG  
994  C CD  . LYS A 131 ? 0.98456 0.89512 1.07951 0.00619  -0.05024 -0.12354 131 LYS A CD  
995  C CE  . LYS A 131 ? 1.22156 1.12952 1.33607 -0.00549 -0.04863 -0.12950 131 LYS A CE  
996  N NZ  . LYS A 131 ? 0.90019 0.80657 1.02053 -0.01450 -0.03589 -0.12292 131 LYS A NZ  
997  N N   . VAL A 132 ? 0.56884 0.51261 0.65882 0.03111  -0.04856 -0.10739 132 VAL A N   
998  C CA  . VAL A 132 ? 0.58361 0.52281 0.66621 0.03203  -0.04091 -0.09826 132 VAL A CA  
999  C C   . VAL A 132 ? 0.69947 0.64386 0.77845 0.04170  -0.03977 -0.09044 132 VAL A C   
1000 O O   . VAL A 132 ? 0.60929 0.55048 0.68671 0.04167  -0.03279 -0.08285 132 VAL A O   
1001 C CB  . VAL A 132 ? 0.61485 0.55023 0.70681 0.02296  -0.03332 -0.09711 132 VAL A CB  
1002 C CG1 . VAL A 132 ? 0.59627 0.52365 0.68681 0.01438  -0.03198 -0.10136 132 VAL A CG1 
1003 C CG2 . VAL A 132 ? 0.67689 0.61979 0.78406 0.02295  -0.03214 -0.09832 132 VAL A CG2 
1004 N N   . HIS A 133 ? 0.71396 0.66592 0.79246 0.05019  -0.04646 -0.09186 133 HIS A N   
1005 C CA  . HIS A 133 ? 0.65946 0.61366 0.72883 0.06185  -0.04523 -0.08214 133 HIS A CA  
1006 C C   . HIS A 133 ? 0.73503 0.69235 0.78359 0.07347  -0.05034 -0.08195 133 HIS A C   
1007 O O   . HIS A 133 ? 0.65551 0.61454 0.69145 0.08523  -0.04896 -0.07277 133 HIS A O   
1008 C CB  . HIS A 133 ? 0.57821 0.53836 0.65802 0.06711  -0.04951 -0.08223 133 HIS A CB  
1009 C CG  . HIS A 133 ? 0.63097 0.58680 0.72695 0.06066  -0.04174 -0.07865 133 HIS A CG  
1010 N ND1 . HIS A 133 ? 0.64337 0.60013 0.75519 0.04957  -0.03961 -0.08669 133 HIS A ND1 
1011 C CD2 . HIS A 133 ? 0.67038 0.61981 0.76876 0.06423  -0.03517 -0.06839 133 HIS A CD2 
1012 C CE1 . HIS A 133 ? 0.55511 0.50760 0.67708 0.04764  -0.03304 -0.08319 133 HIS A CE1 
1013 N NE2 . HIS A 133 ? 0.60773 0.55479 0.72341 0.05587  -0.03075 -0.07253 133 HIS A NE2 
1014 N N   . THR A 134 ? 0.62090 0.57761 0.66421 0.07135  -0.05565 -0.09164 134 THR A N   
1015 C CA  . THR A 134 ? 0.61651 0.57561 0.63888 0.08290  -0.06008 -0.09378 134 THR A CA  
1016 C C   . THR A 134 ? 0.71224 0.66855 0.72414 0.08527  -0.04841 -0.08303 134 THR A C   
1017 O O   . THR A 134 ? 0.68664 0.63789 0.70687 0.07574  -0.04273 -0.08290 134 THR A O   
1018 C CB  . THR A 134 ? 0.70781 0.66440 0.73148 0.07902  -0.06918 -0.10872 134 THR A CB  
1019 O OG1 . THR A 134 ? 0.66044 0.62177 0.70003 0.07496  -0.07884 -0.11907 134 THR A OG1 
1020 C CG2 . THR A 134 ? 0.65300 0.61187 0.65421 0.09248  -0.07483 -0.11388 134 THR A CG2 
1021 N N   . PRO A 135 ? 0.71349 0.67380 0.70795 0.09810  -0.04409 -0.07361 135 PRO A N   
1022 C CA  . PRO A 135 ? 0.82439 0.78435 0.81539 0.09855  -0.02998 -0.06203 135 PRO A CA  
1023 C C   . PRO A 135 ? 0.72535 0.68543 0.71565 0.09559  -0.02878 -0.06907 135 PRO A C   
1024 O O   . PRO A 135 ? 0.77287 0.73224 0.77587 0.08778  -0.01998 -0.06442 135 PRO A O   
1025 C CB  . PRO A 135 ? 0.77217 0.73668 0.73959 0.11512  -0.02612 -0.05186 135 PRO A CB  
1026 C CG  . PRO A 135 ? 0.83746 0.80301 0.79977 0.12239  -0.03783 -0.05467 135 PRO A CG  
1027 C CD  . PRO A 135 ? 0.72180 0.68709 0.70254 0.11189  -0.05021 -0.07063 135 PRO A CD  
1028 N N   . TRP A 136 ? 0.76394 0.72469 0.74135 0.10213  -0.03841 -0.08134 136 TRP A N   
1029 C CA  . TRP A 136 ? 0.71369 0.67277 0.69031 0.10125  -0.03734 -0.08767 136 TRP A CA  
1030 C C   . TRP A 136 ? 0.70152 0.65149 0.69628 0.08691  -0.04000 -0.09282 136 TRP A C   
1031 O O   . TRP A 136 ? 0.71129 0.65971 0.70952 0.08501  -0.03662 -0.09360 136 TRP A O   
1032 C CB  . TRP A 136 ? 0.65033 0.61003 0.60787 0.11329  -0.04714 -0.10058 136 TRP A CB  
1033 C CG  . TRP A 136 ? 0.73434 0.68706 0.69620 0.10942  -0.06234 -0.11544 136 TRP A CG  
1034 C CD1 . TRP A 136 ? 0.86291 0.81961 0.81944 0.11509  -0.07320 -0.12214 136 TRP A CD1 
1035 C CD2 . TRP A 136 ? 0.73821 0.67896 0.71225 0.09928  -0.06830 -0.12561 136 TRP A CD2 
1036 N NE1 . TRP A 136 ? 0.62464 0.57428 0.59382 0.10730  -0.08508 -0.13696 136 TRP A NE1 
1037 C CE2 . TRP A 136 ? 0.75121 0.68928 0.73028 0.09719  -0.08117 -0.13805 136 TRP A CE2 
1038 C CE3 . TRP A 136 ? 0.72870 0.66040 0.71013 0.09234  -0.06417 -0.12496 136 TRP A CE3 
1039 C CZ2 . TRP A 136 ? 0.79240 0.71738 0.78490 0.08673  -0.08758 -0.14842 136 TRP A CZ2 
1040 C CZ3 . TRP A 136 ? 0.68528 0.60227 0.67509 0.08402  -0.07137 -0.13424 136 TRP A CZ3 
1041 C CH2 . TRP A 136 ? 0.66775 0.58070 0.66370 0.08039  -0.08176 -0.14511 136 TRP A CH2 
1042 N N   . ILE A 137 ? 0.72634 0.67119 0.73217 0.07794  -0.04539 -0.09586 137 ILE A N   
1043 C CA  . ILE A 137 ? 0.70320 0.63899 0.72257 0.06519  -0.04557 -0.09850 137 ILE A CA  
1044 C C   . ILE A 137 ? 0.69095 0.62849 0.72146 0.05870  -0.03615 -0.08912 137 ILE A C   
1045 O O   . ILE A 137 ? 0.65421 0.58691 0.68979 0.05291  -0.03479 -0.09005 137 ILE A O   
1046 C CB  . ILE A 137 ? 0.64618 0.57782 0.67485 0.05785  -0.05242 -0.10522 137 ILE A CB  
1047 C CG1 . ILE A 137 ? 0.67330 0.60255 0.69557 0.06276  -0.06329 -0.11751 137 ILE A CG1 
1048 C CG2 . ILE A 137 ? 0.53590 0.45821 0.57560 0.04522  -0.04929 -0.10502 137 ILE A CG2 
1049 C CD1 . ILE A 137 ? 0.65777 0.58313 0.69513 0.05324  -0.06947 -0.12591 137 ILE A CD1 
1050 N N   . GLN A 138 ? 0.56976 0.51314 0.60419 0.06027  -0.03042 -0.08055 138 GLN A N   
1051 C CA  . GLN A 138 ? 0.57413 0.51848 0.62183 0.05416  -0.02177 -0.07312 138 GLN A CA  
1052 C C   . GLN A 138 ? 0.53752 0.48763 0.58609 0.05685  -0.01563 -0.07015 138 GLN A C   
1053 O O   . GLN A 138 ? 0.71023 0.66038 0.77061 0.05040  -0.01390 -0.07144 138 GLN A O   
1054 C CB  . GLN A 138 ? 0.61131 0.55742 0.66355 0.05615  -0.01660 -0.06393 138 GLN A CB  
1055 C CG  . GLN A 138 ? 0.62074 0.56394 0.67755 0.05387  -0.02228 -0.06731 138 GLN A CG  
1056 C CD  . GLN A 138 ? 0.68735 0.62972 0.75030 0.05657  -0.01716 -0.05778 138 GLN A CD  
1057 O OE1 . GLN A 138 ? 0.84119 0.78461 0.89796 0.06340  -0.01054 -0.04731 138 GLN A OE1 
1058 N NE2 . GLN A 138 ? 0.60539 0.54500 0.68056 0.05176  -0.01901 -0.06069 138 GLN A NE2 
1059 N N   . ARG A 139 ? 0.58114 0.53796 0.61761 0.06734  -0.01233 -0.06688 139 ARG A N   
1060 C CA  . ARG A 139 ? 0.65450 0.62040 0.69496 0.07054  -0.00436 -0.06391 139 ARG A CA  
1061 C C   . ARG A 139 ? 0.57980 0.54408 0.62157 0.06960  -0.01083 -0.07382 139 ARG A C   
1062 O O   . ARG A 139 ? 0.70701 0.67809 0.76250 0.06716  -0.00705 -0.07368 139 ARG A O   
1063 C CB  . ARG A 139 ? 0.54248 0.51619 0.56567 0.08378  0.00146  -0.05896 139 ARG A CB  
1064 C CG  . ARG A 139 ? 0.80111 0.77602 0.82163 0.08668  0.01083  -0.04515 139 ARG A CG  
1065 C CD  . ARG A 139 ? 0.87356 0.85646 0.87205 0.10167  0.01814  -0.03914 139 ARG A CD  
1066 N NE  . ARG A 139 ? 1.22061 1.19936 1.20152 0.10988  0.01753  -0.03104 139 ARG A NE  
1067 C CZ  . ARG A 139 ? 1.11807 1.09854 1.07123 0.12438  0.01042  -0.03517 139 ARG A CZ  
1068 N NH1 . ARG A 139 ? 1.01863 1.00332 0.95884 0.13165  0.00359  -0.04821 139 ARG A NH1 
1069 N NH2 . ARG A 139 ? 0.96431 0.94164 0.90218 0.13290  0.00891  -0.02707 139 ARG A NH2 
1070 N N   . LEU A 140 ? 0.57272 0.52756 0.60198 0.07172  -0.02109 -0.08269 140 LEU A N   
1071 C CA  . LEU A 140 ? 0.56849 0.51672 0.59691 0.07155  -0.02756 -0.09064 140 LEU A CA  
1072 C C   . LEU A 140 ? 0.62898 0.57165 0.66932 0.06122  -0.02908 -0.09042 140 LEU A C   
1073 O O   . LEU A 140 ? 0.58729 0.53117 0.63215 0.06216  -0.03076 -0.09285 140 LEU A O   
1074 C CB  . LEU A 140 ? 0.70058 0.63646 0.71545 0.07444  -0.03728 -0.09946 140 LEU A CB  
1075 C CG  . LEU A 140 ? 0.83490 0.75627 0.84754 0.07283  -0.04444 -0.10620 140 LEU A CG  
1076 C CD1 . LEU A 140 ? 0.68022 0.60525 0.68776 0.08417  -0.04494 -0.11031 140 LEU A CD1 
1077 C CD2 . LEU A 140 ? 0.71630 0.62311 0.72319 0.06983  -0.05234 -0.11330 140 LEU A CD2 
1078 N N   . PHE A 141 ? 0.58557 0.52309 0.63020 0.05286  -0.02906 -0.08833 141 PHE A N   
1079 C CA  . PHE A 141 ? 0.58884 0.52143 0.64132 0.04446  -0.03003 -0.08901 141 PHE A CA  
1080 C C   . PHE A 141 ? 0.56715 0.51102 0.63530 0.04283  -0.02512 -0.08640 141 PHE A C   
1081 O O   . PHE A 141 ? 0.65574 0.60009 0.72802 0.04183  -0.02869 -0.09013 141 PHE A O   
1082 C CB  . PHE A 141 ? 0.59011 0.51702 0.64482 0.03720  -0.02960 -0.08822 141 PHE A CB  
1083 C CG  . PHE A 141 ? 0.52520 0.44813 0.58565 0.02985  -0.02920 -0.08942 141 PHE A CG  
1084 C CD1 . PHE A 141 ? 0.52625 0.43816 0.57715 0.02754  -0.03300 -0.09262 141 PHE A CD1 
1085 C CD2 . PHE A 141 ? 0.55084 0.47951 0.62470 0.02607  -0.02478 -0.08735 141 PHE A CD2 
1086 C CE1 . PHE A 141 ? 0.49349 0.40212 0.54469 0.02287  -0.03245 -0.09399 141 PHE A CE1 
1087 C CE2 . PHE A 141 ? 0.52841 0.45366 0.60564 0.02076  -0.02546 -0.09092 141 PHE A CE2 
1088 C CZ  . PHE A 141 ? 0.56079 0.47699 0.62492 0.01982  -0.02934 -0.09436 141 PHE A CZ  
1089 N N   . LEU A 142 ? 0.55728 0.51010 0.63499 0.04298  -0.01718 -0.08002 142 LEU A N   
1090 C CA  . LEU A 142 ? 0.59899 0.56192 0.69747 0.03914  -0.01126 -0.07765 142 LEU A CA  
1091 C C   . LEU A 142 ? 0.60334 0.57850 0.70893 0.04421  -0.01086 -0.08044 142 LEU A C   
1092 O O   . LEU A 142 ? 0.56286 0.54705 0.68859 0.04014  -0.01029 -0.08310 142 LEU A O   
1093 C CB  . LEU A 142 ? 0.53075 0.49707 0.63716 0.03841  -0.00089 -0.06774 142 LEU A CB  
1094 C CG  . LEU A 142 ? 0.63709 0.59360 0.74537 0.03316  -0.00072 -0.06521 142 LEU A CG  
1095 C CD1 . LEU A 142 ? 0.50082 0.45727 0.60915 0.03671  0.00830  -0.05351 142 LEU A CD1 
1096 C CD2 . LEU A 142 ? 0.49114 0.44583 0.61802 0.02412  -0.00187 -0.07020 142 LEU A CD2 
1097 N N   . ALA A 143 ? 0.67947 0.65590 0.77073 0.05356  -0.01221 -0.08173 143 ALA A N   
1098 C CA  . ALA A 143 ? 0.63049 0.61965 0.72880 0.06047  -0.01184 -0.08536 143 ALA A CA  
1099 C C   . ALA A 143 ? 0.67699 0.66077 0.77284 0.06214  -0.02360 -0.09391 143 ALA A C   
1100 O O   . ALA A 143 ? 0.63699 0.63276 0.74245 0.06839  -0.02519 -0.09815 143 ALA A O   
1101 C CB  . ALA A 143 ? 0.60462 0.59659 0.68681 0.07193  -0.00863 -0.08469 143 ALA A CB  
1102 N N   . LEU A 144 ? 0.55411 0.52073 0.63717 0.05776  -0.03121 -0.09596 144 LEU A N   
1103 C CA  . LEU A 144 ? 0.57567 0.53419 0.65170 0.06046  -0.04143 -0.10156 144 LEU A CA  
1104 C C   . LEU A 144 ? 0.56215 0.53119 0.65593 0.05628  -0.04430 -0.10513 144 LEU A C   
1105 O O   . LEU A 144 ? 0.54653 0.52198 0.65573 0.04804  -0.03888 -0.10352 144 LEU A O   
1106 C CB  . LEU A 144 ? 0.49479 0.43122 0.55074 0.05671  -0.04573 -0.10086 144 LEU A CB  
1107 C CG  . LEU A 144 ? 0.54671 0.47076 0.58751 0.05995  -0.04607 -0.10049 144 LEU A CG  
1108 C CD1 . LEU A 144 ? 0.52297 0.43031 0.55407 0.05193  -0.04699 -0.09905 144 LEU A CD1 
1109 C CD2 . LEU A 144 ? 0.47274 0.38983 0.50395 0.07059  -0.05233 -0.10455 144 LEU A CD2 
1110 N N   . PRO A 145 ? 0.55376 0.52383 0.64571 0.06268  -0.05399 -0.11088 145 PRO A N   
1111 C CA  . PRO A 145 ? 0.59248 0.57434 0.70148 0.05998  -0.05960 -0.11716 145 PRO A CA  
1112 C C   . PRO A 145 ? 0.60630 0.57663 0.70784 0.05121  -0.06035 -0.11731 145 PRO A C   
1113 O O   . PRO A 145 ? 0.61950 0.57119 0.69885 0.04922  -0.05913 -0.11301 145 PRO A O   
1114 C CB  . PRO A 145 ? 0.51483 0.49520 0.61392 0.07174  -0.07229 -0.12267 145 PRO A CB  
1115 C CG  . PRO A 145 ? 0.53178 0.50584 0.61912 0.08082  -0.07056 -0.11963 145 PRO A CG  
1116 C CD  . PRO A 145 ? 0.56391 0.52392 0.63859 0.07393  -0.06147 -0.11270 145 PRO A CD  
1117 N N   . LEU A 146 ? 0.58693 0.56967 0.71008 0.04584  -0.06206 -0.12351 146 LEU A N   
1118 C CA  . LEU A 146 ? 0.59093 0.56479 0.70979 0.03845  -0.06247 -0.12591 146 LEU A CA  
1119 C C   . LEU A 146 ? 0.64070 0.59730 0.72742 0.04327  -0.07009 -0.12694 146 LEU A C   
1120 O O   . LEU A 146 ? 0.58392 0.52654 0.65541 0.03860  -0.06533 -0.12337 146 LEU A O   
1121 C CB  . LEU A 146 ? 0.59691 0.58669 0.74534 0.03365  -0.06622 -0.13593 146 LEU A CB  
1122 C CG  . LEU A 146 ? 0.82723 0.82380 1.00461 0.02335  -0.05455 -0.13265 146 LEU A CG  
1123 C CD1 . LEU A 146 ? 0.64955 0.66280 0.86231 0.01827  -0.05912 -0.14413 146 LEU A CD1 
1124 C CD2 . LEU A 146 ? 0.62716 0.60687 0.79168 0.01756  -0.04885 -0.12842 146 LEU A CD2 
1125 N N   . PHE A 147 ? 0.59727 0.55472 0.67329 0.05333  -0.08123 -0.13114 147 PHE A N   
1126 C CA  . PHE A 147 ? 0.55924 0.49791 0.60131 0.05883  -0.08691 -0.12967 147 PHE A CA  
1127 C C   . PHE A 147 ? 0.60286 0.52071 0.62298 0.05787  -0.07916 -0.11859 147 PHE A C   
1128 O O   . PHE A 147 ? 0.60146 0.50250 0.59873 0.05600  -0.07626 -0.11450 147 PHE A O   
1129 C CB  . PHE A 147 ? 0.61801 0.56032 0.65071 0.07216  -0.10160 -0.13537 147 PHE A CB  
1130 C CG  . PHE A 147 ? 0.79450 0.73426 0.82335 0.08187  -0.10423 -0.13091 147 PHE A CG  
1131 C CD1 . PHE A 147 ? 0.69426 0.65418 0.75260 0.08261  -0.10232 -0.13379 147 PHE A CD1 
1132 C CD2 . PHE A 147 ? 0.67806 0.59458 0.67389 0.09109  -0.10805 -0.12393 147 PHE A CD2 
1133 C CE1 . PHE A 147 ? 0.73457 0.69283 0.78915 0.09339  -0.10494 -0.13156 147 PHE A CE1 
1134 C CE2 . PHE A 147 ? 0.67979 0.59158 0.67263 0.10132  -0.11147 -0.12114 147 PHE A CE2 
1135 C CZ  . PHE A 147 ? 0.62096 0.55449 0.64317 0.10300  -0.11039 -0.12596 147 PHE A CZ  
1136 N N   . ILE A 148 ? 0.58176 0.50137 0.61023 0.05852  -0.07482 -0.11446 148 ILE A N   
1137 C CA  . ILE A 148 ? 0.73631 0.63706 0.74836 0.05656  -0.06878 -0.10669 148 ILE A CA  
1138 C C   . ILE A 148 ? 0.71656 0.61543 0.73311 0.04532  -0.05924 -0.10410 148 ILE A C   
1139 O O   . ILE A 148 ? 0.60456 0.48783 0.60579 0.04142  -0.05521 -0.09991 148 ILE A O   
1140 C CB  . ILE A 148 ? 0.62311 0.52685 0.64165 0.06186  -0.06812 -0.10566 148 ILE A CB  
1141 C CG1 . ILE A 148 ? 0.67468 0.58093 0.69026 0.07477  -0.07796 -0.10904 148 ILE A CG1 
1142 C CG2 . ILE A 148 ? 0.62220 0.50631 0.62659 0.05934  -0.06380 -0.10053 148 ILE A CG2 
1143 C CD1 . ILE A 148 ? 0.55211 0.43388 0.53973 0.08168  -0.08410 -0.10514 148 ILE A CD1 
1144 N N   . ARG A 149 ? 0.61717 0.53192 0.65627 0.04024  -0.05493 -0.10619 149 ARG A N   
1145 C CA  . ARG A 149 ? 0.63404 0.54757 0.67880 0.03166  -0.04701 -0.10394 149 ARG A CA  
1146 C C   . ARG A 149 ? 0.66135 0.56779 0.69622 0.02805  -0.04664 -0.10638 149 ARG A C   
1147 O O   . ARG A 149 ? 0.60068 0.49990 0.63076 0.02293  -0.04040 -0.10363 149 ARG A O   
1148 C CB  . ARG A 149 ? 0.60711 0.53615 0.67673 0.02840  -0.04258 -0.10443 149 ARG A CB  
1149 C CG  . ARG A 149 ? 0.58483 0.51960 0.65982 0.03143  -0.03840 -0.09958 149 ARG A CG  
1150 C CD  . ARG A 149 ? 0.54857 0.49693 0.64649 0.02847  -0.03178 -0.09742 149 ARG A CD  
1151 N NE  . ARG A 149 ? 0.50873 0.47167 0.62319 0.03117  -0.03332 -0.10075 149 ARG A NE  
1152 C CZ  . ARG A 149 ? 0.61550 0.59005 0.75556 0.02616  -0.02932 -0.10190 149 ARG A CZ  
1153 N NH1 . ARG A 149 ? 0.43297 0.40337 0.58271 0.01904  -0.02392 -0.09957 149 ARG A NH1 
1154 N NH2 . ARG A 149 ? 0.48758 0.47823 0.64662 0.02834  -0.03069 -0.10595 149 ARG A NH2 
1155 N N   . HIS A 150 ? 0.66684 0.57697 0.69901 0.03155  -0.05352 -0.11270 150 HIS A N   
1156 C CA  . HIS A 150 ? 0.54036 0.44384 0.55805 0.03054  -0.05341 -0.11616 150 HIS A CA  
1157 C C   . HIS A 150 ? 0.72425 0.60963 0.71423 0.03191  -0.04965 -0.10892 150 HIS A C   
1158 O O   . HIS A 150 ? 0.70232 0.58174 0.68531 0.02710  -0.04174 -0.10729 150 HIS A O   
1159 C CB  . HIS A 150 ? 0.67507 0.58600 0.69128 0.03667  -0.06437 -0.12583 150 HIS A CB  
1160 C CG  . HIS A 150 ? 0.57347 0.49774 0.61515 0.03181  -0.06569 -0.13576 150 HIS A CG  
1161 N ND1 . HIS A 150 ? 0.84507 0.76628 0.88839 0.02655  -0.06013 -0.13938 150 HIS A ND1 
1162 C CD2 . HIS A 150 ? 0.65709 0.59719 0.72614 0.03119  -0.07156 -0.14338 150 HIS A CD2 
1163 C CE1 . HIS A 150 ? 0.84582 0.77765 0.91541 0.02295  -0.06314 -0.14879 150 HIS A CE1 
1164 N NE2 . HIS A 150 ? 0.82445 0.76815 0.91123 0.02477  -0.06965 -0.15111 150 HIS A NE2 
1165 N N   . ARG A 151 ? 0.65062 0.52669 0.62645 0.03849  -0.05428 -0.10428 151 ARG A N   
1166 C CA  . ARG A 151 ? 0.66837 0.52356 0.61908 0.03927  -0.04979 -0.09582 151 ARG A CA  
1167 C C   . ARG A 151 ? 0.63412 0.48395 0.59366 0.02989  -0.03960 -0.09081 151 ARG A C   
1168 O O   . ARG A 151 ? 0.67923 0.51843 0.62828 0.02495  -0.03094 -0.08616 151 ARG A O   
1169 C CB  . ARG A 151 ? 0.65159 0.49571 0.58795 0.04928  -0.05780 -0.09209 151 ARG A CB  
1170 C CG  . ARG A 151 ? 0.72219 0.56413 0.63758 0.06056  -0.06755 -0.09442 151 ARG A CG  
1171 C CD  . ARG A 151 ? 0.72895 0.57551 0.64738 0.07215  -0.08007 -0.09722 151 ARG A CD  
1172 N NE  . ARG A 151 ? 1.02495 0.84813 0.92289 0.07916  -0.08097 -0.08790 151 ARG A NE  
1173 C CZ  . ARG A 151 ? 1.12080 0.93749 1.00314 0.09376  -0.09237 -0.08723 151 ARG A CZ  
1174 N NH1 . ARG A 151 ? 1.03865 0.87361 0.92499 0.10300  -0.10500 -0.09662 151 ARG A NH1 
1175 N NH2 . ARG A 151 ? 1.08782 0.87882 0.95190 0.09961  -0.09187 -0.07764 151 ARG A NH2 
1176 N N   . ILE A 152 ? 0.63881 0.49720 0.61788 0.02792  -0.04038 -0.09214 152 ILE A N   
1177 C CA  . ILE A 152 ? 0.71774 0.57410 0.70678 0.02047  -0.03364 -0.08989 152 ILE A CA  
1178 C C   . ILE A 152 ? 0.69193 0.55539 0.68962 0.01331  -0.02603 -0.09145 152 ILE A C   
1179 O O   . ILE A 152 ? 0.71112 0.56886 0.70933 0.00709  -0.01876 -0.08894 152 ILE A O   
1180 C CB  . ILE A 152 ? 0.67270 0.53954 0.67759 0.02242  -0.03689 -0.09211 152 ILE A CB  
1181 C CG1 . ILE A 152 ? 0.52091 0.38001 0.51739 0.03034  -0.04337 -0.09164 152 ILE A CG1 
1182 C CG2 . ILE A 152 ? 0.56442 0.43287 0.58030 0.01618  -0.03232 -0.09205 152 ILE A CG2 
1183 C CD1 . ILE A 152 ? 0.58066 0.45200 0.58938 0.03465  -0.04568 -0.09442 152 ILE A CD1 
1184 N N   . ALA A 153 ? 0.53981 0.41603 0.54717 0.01406  -0.02740 -0.09636 153 ALA A N   
1185 C CA  . ALA A 153 ? 0.61314 0.49623 0.63149 0.00892  -0.02099 -0.09905 153 ALA A CA  
1186 C C   . ALA A 153 ? 0.57736 0.45324 0.57971 0.00755  -0.01481 -0.09908 153 ALA A C   
1187 O O   . ALA A 153 ? 0.62666 0.50367 0.63459 0.00240  -0.00624 -0.09851 153 ALA A O   
1188 C CB  . ALA A 153 ? 0.48685 0.38190 0.52089 0.01019  -0.02422 -0.10448 153 ALA A CB  
1189 N N   . ALA A 154 ? 0.73533 0.60522 0.71739 0.01326  -0.01894 -0.10003 154 ALA A N   
1190 C CA  . ALA A 154 ? 0.64654 0.50822 0.60642 0.01420  -0.01221 -0.09869 154 ALA A CA  
1191 C C   . ALA A 154 ? 0.75281 0.60153 0.70440 0.00914  -0.00207 -0.08900 154 ALA A C   
1192 O O   . ALA A 154 ? 0.84572 0.69296 0.79239 0.00530  0.00961  -0.08713 154 ALA A O   
1193 C CB  . ALA A 154 ? 0.70715 0.56360 0.64254 0.02390  -0.02093 -0.10069 154 ALA A CB  
1194 N N   . ARG A 155 ? 0.60139 0.44086 0.55360 0.00884  -0.00567 -0.08347 155 ARG A N   
1195 C CA  . ARG A 155 ? 0.71083 0.53635 0.66049 0.00242  0.00344  -0.07536 155 ARG A CA  
1196 C C   . ARG A 155 ? 0.71097 0.54785 0.68812 -0.00718 0.01026  -0.07830 155 ARG A C   
1197 O O   . ARG A 155 ? 0.79509 0.62797 0.77510 -0.01445 0.02214  -0.07441 155 ARG A O   
1198 C CB  . ARG A 155 ? 0.70951 0.52064 0.65422 0.00552  -0.00380 -0.07102 155 ARG A CB  
1199 C CG  . ARG A 155 ? 0.75504 0.54820 0.70072 -0.00208 0.00449  -0.06357 155 ARG A CG  
1200 C CD  . ARG A 155 ? 0.86599 0.64101 0.78628 -0.00253 0.01613  -0.05293 155 ARG A CD  
1201 N NE  . ARG A 155 ? 1.14469 0.89256 1.05380 -0.00318 0.01826  -0.04306 155 ARG A NE  
1202 C CZ  . ARG A 155 ? 1.12540 0.86424 1.05414 -0.01321 0.02266  -0.04189 155 ARG A CZ  
1203 N NH1 . ARG A 155 ? 1.08959 0.84631 1.04966 -0.02308 0.02504  -0.05001 155 ARG A NH1 
1204 N NH2 . ARG A 155 ? 1.11002 0.82047 1.02731 -0.01275 0.02386  -0.03302 155 ARG A NH2 
1205 N N   . MET A 156 ? 0.65342 0.50506 0.65155 -0.00681 0.00326  -0.08473 156 MET A N   
1206 C CA  . MET A 156 ? 0.71795 0.58142 0.74091 -0.01335 0.00738  -0.08806 156 MET A CA  
1207 C C   . MET A 156 ? 0.75022 0.62386 0.77900 -0.01565 0.01664  -0.09100 156 MET A C   
1208 O O   . MET A 156 ? 0.78471 0.66571 0.83100 -0.02184 0.02400  -0.09225 156 MET A O   
1209 C CB  . MET A 156 ? 0.66703 0.54214 0.70577 -0.00997 -0.00206 -0.09248 156 MET A CB  
1210 C CG  . MET A 156 ? 0.69229 0.55990 0.72789 -0.00724 -0.01003 -0.09140 156 MET A CG  
1211 S SD  . MET A 156 ? 0.73370 0.61565 0.78147 -0.00094 -0.01861 -0.09498 156 MET A SD  
1212 C CE  . MET A 156 ? 0.67213 0.56820 0.74138 -0.00485 -0.01537 -0.09842 156 MET A CE  
1213 N N   . ARG A 157 ? 0.69496 0.57023 0.71112 -0.01025 0.01592  -0.09372 157 ARG A N   
1214 C CA  . ARG A 157 ? 0.74461 0.62837 0.76417 -0.01083 0.02478  -0.09820 157 ARG A CA  
1215 C C   . ARG A 157 ? 0.73133 0.60812 0.73782 -0.01483 0.03900  -0.09275 157 ARG A C   
1216 O O   . ARG A 157 ? 0.76110 0.64768 0.78208 -0.01922 0.04995  -0.09476 157 ARG A O   
1217 C CB  . ARG A 157 ? 0.66060 0.54636 0.66962 -0.00371 0.01905  -0.10473 157 ARG A CB  
1218 C CG  . ARG A 157 ? 0.71801 0.61262 0.74728 -0.00176 0.00968  -0.10996 157 ARG A CG  
1219 C CD  . ARG A 157 ? 0.61756 0.51514 0.64489 0.00290  0.00606  -0.11903 157 ARG A CD  
1220 N NE  . ARG A 157 ? 0.82876 0.72005 0.83452 0.00784  -0.00103 -0.12063 157 ARG A NE  
1221 C CZ  . ARG A 157 ? 0.80944 0.70185 0.81947 0.01020  -0.01165 -0.12176 157 ARG A CZ  
1222 N NH1 . ARG A 157 ? 0.70347 0.60151 0.73569 0.00781  -0.01460 -0.11988 157 ARG A NH1 
1223 N NH2 . ARG A 157 ? 0.72393 0.61284 0.71532 0.01606  -0.01923 -0.12482 157 ARG A NH2 
1224 N N   . ALA A 158 ? 0.72373 0.58362 0.70348 -0.01284 0.03984  -0.08503 158 ALA A N   
1225 C CA  . ALA A 158 ? 0.89267 0.74212 0.85686 -0.01661 0.05546  -0.07642 158 ALA A CA  
1226 C C   . ALA A 158 ? 0.81316 0.66273 0.80232 -0.02826 0.06396  -0.07223 158 ALA A C   
1227 O O   . ALA A 158 ? 0.88675 0.73891 0.88145 -0.03477 0.08050  -0.06875 158 ALA A O   
1228 C CB  . ALA A 158 ? 0.71710 0.54519 0.64542 -0.01003 0.05268  -0.06744 158 ALA A CB  
1229 N N   . ASP A 159 ? 0.83906 0.68683 0.84452 -0.03086 0.05303  -0.07346 159 ASP A N   
1230 C CA  . ASP A 159 ? 0.70570 0.55460 0.73785 -0.04166 0.05776  -0.07284 159 ASP A CA  
1231 C C   . ASP A 159 ? 0.82908 0.70232 0.89352 -0.04624 0.06231  -0.08130 159 ASP A C   
1232 O O   . ASP A 159 ? 0.76620 0.64464 0.85397 -0.05619 0.07186  -0.08123 159 ASP A O   
1233 C CB  . ASP A 159 ? 0.70220 0.54477 0.74152 -0.04063 0.04276  -0.07512 159 ASP A CB  
1234 C CG  . ASP A 159 ? 0.99559 0.81187 1.00993 -0.03805 0.04064  -0.06627 159 ASP A CG  
1235 O OD1 . ASP A 159 ? 0.95669 0.75780 0.94902 -0.03844 0.05192  -0.05648 159 ASP A OD1 
1236 O OD2 . ASP A 159 ? 0.75699 0.56745 0.77195 -0.03411 0.02784  -0.06886 159 ASP A OD2 
1237 N N   . SER A 160 ? 0.73867 0.62690 0.80750 -0.03905 0.05546  -0.08889 160 SER A N   
1238 C CA  . SER A 160 ? 0.90263 0.81295 1.00110 -0.04082 0.05868  -0.09676 160 SER A CA  
1239 C C   . SER A 160 ? 0.86858 0.78631 0.96599 -0.04234 0.07604  -0.09681 160 SER A C   
1240 O O   . SER A 160 ? 0.92428 0.85841 1.04997 -0.04782 0.08456  -0.10077 160 SER A O   
1241 C CB  . SER A 160 ? 0.68113 0.60137 0.78526 -0.03206 0.04576  -0.10347 160 SER A CB  
1242 O OG  . SER A 160 ? 1.00912 0.92672 1.11788 -0.03064 0.03221  -0.10362 160 SER A OG  
1243 N N   . LYS A 161 ? 0.87568 0.78350 0.94146 -0.03656 0.08117  -0.09364 161 LYS A N   
1244 C CA  . LYS A 161 ? 0.84815 0.76223 0.90756 -0.03651 0.09921  -0.09362 161 LYS A CA  
1245 C C   . LYS A 161 ? 1.01106 0.92107 1.07665 -0.04749 0.11709  -0.08438 161 LYS A C   
1246 O O   . LYS A 161 ? 1.08737 1.01279 1.17141 -0.05189 0.13326  -0.08636 161 LYS A O   
1247 C CB  . LYS A 161 ? 0.78424 0.68700 0.80361 -0.02657 0.09916  -0.09285 161 LYS A CB  
1248 N N   . ALA A 162 ? 1.04881 0.93807 1.10191 -0.05218 0.11512  -0.07436 162 ALA A N   
1249 C CA  . ALA A 162 ? 1.00612 0.88718 1.06750 -0.06418 0.13253  -0.06432 162 ALA A CA  
1250 C C   . ALA A 162 ? 1.01058 0.90922 1.12179 -0.07582 0.13252  -0.07129 162 ALA A C   
1251 O O   . ALA A 162 ? 1.11316 1.01875 1.24616 -0.08669 0.15098  -0.06809 162 ALA A O   
1252 C CB  . ALA A 162 ? 0.91389 0.76431 0.94815 -0.06464 0.12885  -0.05204 162 ALA A CB  
1253 N N   . ALA A 163 ? 1.00883 0.84069 1.14611 0.29474  0.12641  0.12255  163 ALA A N   
1254 C CA  . ALA A 163 ? 0.98960 0.86402 1.21608 0.26109  0.13540  0.12930  163 ALA A CA  
1255 C C   . ALA A 163 ? 0.91394 0.80752 1.11762 0.26727  0.15744  0.14161  163 ALA A C   
1256 O O   . ALA A 163 ? 1.18222 1.10966 1.44260 0.23724  0.15046  0.12862  163 ALA A O   
1257 C CB  . ALA A 163 ? 0.81293 0.70887 1.08823 0.22292  0.09766  0.07747  163 ALA A CB  
1258 N N   . ASN A 164 ? 0.99948 0.86884 1.11850 0.30759  0.18140  0.16468  164 ASN A N   
1259 C CA  . ASN A 164 ? 1.22399 1.10995 1.32139 0.31661  0.20374  0.17699  164 ASN A CA  
1260 C C   . ASN A 164 ? 1.20841 1.08827 1.31007 0.34707  0.25781  0.24199  164 ASN A C   
1261 O O   . ASN A 164 ? 1.27205 1.15908 1.45242 0.33950  0.27881  0.28089  164 ASN A O   
1262 C CB  . ASN A 164 ? 1.13821 1.00136 1.13108 0.34111  0.18460  0.14403  164 ASN A CB  
1263 N N   . MET A 172 ? 0.94529 1.01683 1.10657 0.20334  0.15533  0.06971  172 MET A N   
1264 C CA  . MET A 172 ? 1.00985 1.10996 1.24159 0.17784  0.15446  0.07955  172 MET A CA  
1265 C C   . MET A 172 ? 1.03406 1.14773 1.23987 0.16986  0.13923  0.05794  172 MET A C   
1266 O O   . MET A 172 ? 1.02300 1.13040 1.18015 0.16841  0.11859  0.02581  172 MET A O   
1267 C CB  . MET A 172 ? 0.91319 1.02118 1.20850 0.14506  0.12994  0.06491  172 MET A CB  
1268 C CG  . MET A 172 ? 0.91273 1.01960 1.28376 0.14385  0.14519  0.09953  172 MET A CG  
1269 S SD  . MET A 172 ? 1.12478 1.25587 1.60815 0.12032  0.14024  0.12285  172 MET A SD  
1270 C CE  . MET A 172 ? 0.75606 0.88031 1.33662 0.11602  0.14687  0.15495  172 MET A CE  
1271 N N   . ASP A 173 ? 0.91402 1.04653 1.16128 0.16480  0.14963  0.07819  173 ASP A N   
1272 C CA  . ASP A 173 ? 0.70105 0.84748 0.93346 0.15582  0.13519  0.06215  173 ASP A CA  
1273 C C   . ASP A 173 ? 0.57597 0.73539 0.84458 0.11978  0.10237  0.03805  173 ASP A C   
1274 O O   . ASP A 173 ? 0.68613 0.84310 0.99568 0.10359  0.09032  0.03434  173 ASP A O   
1275 C CB  . ASP A 173 ? 0.59887 0.75761 0.85992 0.16928  0.16111  0.09518  173 ASP A CB  
1276 C CG  . ASP A 173 ? 0.78932 0.95437 1.01157 0.17356  0.15162  0.08042  173 ASP A CG  
1277 O OD1 . ASP A 173 ? 0.93581 1.10839 1.17145 0.18955  0.17373  0.10448  173 ASP A OD1 
1278 O OD2 . ASP A 173 ? 0.65138 0.81363 0.83407 0.16281  0.12427  0.04705  173 ASP A OD2 
1279 N N   . VAL A 174 ? 0.59334 0.76290 0.84283 0.11022  0.08661  0.02174  174 VAL A N   
1280 C CA  . VAL A 174 ? 0.54196 0.71730 0.80486 0.08261  0.05634  -0.00152 174 VAL A CA  
1281 C C   . VAL A 174 ? 0.56120 0.74435 0.89881 0.06654  0.04599  0.01438  174 VAL A C   
1282 O O   . VAL A 174 ? 0.51117 0.70360 0.89804 0.07410  0.06474  0.04587  174 VAL A O   
1283 C CB  . VAL A 174 ? 0.58318 0.76541 0.80446 0.07940  0.04492  -0.01828 174 VAL A CB  
1284 C CG1 . VAL A 174 ? 0.48113 0.65424 0.64700 0.09601  0.05023  -0.03213 174 VAL A CG1 
1285 C CG2 . VAL A 174 ? 0.49316 0.68870 0.73681 0.08337  0.05193  0.00208  174 VAL A CG2 
1286 N N   . ASN A 175 ? 0.57287 0.74945 0.92044 0.04672  0.01458  -0.00766 175 ASN A N   
1287 C CA  . ASN A 175 ? 0.55148 0.72871 0.96664 0.03080  -0.01023 -0.00085 175 ASN A CA  
1288 C C   . ASN A 175 ? 0.62227 0.80745 1.02161 0.02406  -0.02484 -0.00565 175 ASN A C   
1289 O O   . ASN A 175 ? 0.57229 0.75388 0.90415 0.02250  -0.03343 -0.02892 175 ASN A O   
1290 C CB  . ASN A 175 ? 0.44902 0.60591 0.87025 0.01799  -0.04480 -0.02699 175 ASN A CB  
1291 C CG  . ASN A 175 ? 0.55771 0.70721 1.05940 0.00432  -0.07946 -0.02124 175 ASN A CG  
1292 O OD1 . ASN A 175 ? 0.57151 0.71816 1.07053 -0.00357 -0.10567 -0.02925 175 ASN A OD1 
1293 N ND2 . ASN A 175 ? 0.67228 0.81556 1.25049 0.00181  -0.08411 -0.00763 175 ASN A ND2 
1294 N N   . PRO A 176 ? 0.57778 0.77420 1.04341 0.02072  -0.02614 0.01851  176 PRO A N   
1295 C CA  . PRO A 176 ? 0.44242 0.64557 0.89597 0.01442  -0.04201 0.01481  176 PRO A CA  
1296 C C   . PRO A 176 ? 0.49241 0.67644 0.91695 -0.00044 -0.08697 -0.01447 176 PRO A C   
1297 O O   . PRO A 176 ? 0.62621 0.81033 0.99654 -0.00205 -0.09543 -0.02632 176 PRO A O   
1298 C CB  . PRO A 176 ? 0.42740 0.64462 0.97836 0.01399  -0.03509 0.04887  176 PRO A CB  
1299 C CG  . PRO A 176 ? 0.55605 0.77940 1.14428 0.02914  0.00450  0.07675  176 PRO A CG  
1300 C CD  . PRO A 176 ? 0.44266 0.64804 1.00201 0.02491  -0.00757 0.05493  176 PRO A CD  
1301 N N   . GLN A 177 ? 0.53253 0.69640 0.98980 -0.00856 -0.11729 -0.02586 177 GLN A N   
1302 C CA  . GLN A 177 ? 0.64617 0.78203 1.06013 -0.01546 -0.16248 -0.05657 177 GLN A CA  
1303 C C   . GLN A 177 ? 0.56491 0.69096 0.87585 -0.00813 -0.15202 -0.08281 177 GLN A C   
1304 O O   . GLN A 177 ? 0.59625 0.70473 0.84342 -0.00748 -0.17293 -0.10217 177 GLN A O   
1305 C CB  . GLN A 177 ? 0.51799 0.62875 0.99531 -0.02186 -0.20291 -0.06486 177 GLN A CB  
1306 N N   . ALA A 178 ? 0.55097 0.68651 0.84662 -0.00063 -0.11893 -0.08153 178 ALA A N   
1307 C CA  . ALA A 178 ? 0.68071 0.81136 0.89539 0.00669  -0.10455 -0.10210 178 ALA A CA  
1308 C C   . ALA A 178 ? 0.59547 0.74281 0.76805 0.00960  -0.08667 -0.09610 178 ALA A C   
1309 O O   . ALA A 178 ? 0.63506 0.77515 0.74667 0.01264  -0.08598 -0.11065 178 ALA A O   
1310 C CB  . ALA A 178 ? 0.46353 0.59867 0.68414 0.01393  -0.07852 -0.10116 178 ALA A CB  
1311 N N   . VAL A 179 ? 0.53379 0.70230 0.74069 0.01098  -0.07068 -0.07316 179 VAL A N   
1312 C CA  . VAL A 179 ? 0.51266 0.69495 0.68988 0.01366  -0.06056 -0.06779 179 VAL A CA  
1313 C C   . VAL A 179 ? 0.57368 0.74639 0.72793 0.00529  -0.08747 -0.07405 179 VAL A C   
1314 O O   . VAL A 179 ? 0.56653 0.73668 0.66795 0.00719  -0.08461 -0.08177 179 VAL A O   
1315 C CB  . VAL A 179 ? 0.52328 0.72445 0.74054 0.02080  -0.04200 -0.04388 179 VAL A CB  
1316 C CG1 . VAL A 179 ? 0.37877 0.59131 0.57332 0.02309  -0.03986 -0.04012 179 VAL A CG1 
1317 C CG2 . VAL A 179 ? 0.45971 0.66276 0.67683 0.03574  -0.01478 -0.03843 179 VAL A CG2 
1318 N N   . VAL A 180 ? 0.50258 0.66752 0.69981 -0.00269 -0.11488 -0.06893 180 VAL A N   
1319 C CA  . VAL A 180 ? 0.57369 0.72330 0.74674 -0.00833 -0.14694 -0.07499 180 VAL A CA  
1320 C C   . VAL A 180 ? 0.56145 0.68176 0.65666 -0.00299 -0.16075 -0.09940 180 VAL A C   
1321 O O   . VAL A 180 ? 0.71833 0.82863 0.75591 0.00004  -0.16700 -0.10270 180 VAL A O   
1322 C CB  . VAL A 180 ? 0.68650 0.82838 0.93272 -0.01700 -0.18072 -0.06688 180 VAL A CB  
1323 C CG1 . VAL A 180 ? 0.58232 0.69889 0.79656 -0.02044 -0.22312 -0.07704 180 VAL A CG1 
1324 C CG2 . VAL A 180 ? 0.67328 0.84559 0.99320 -0.01800 -0.15864 -0.03838 180 VAL A CG2 
1325 N N   . ASP A 181 ? 0.62594 0.73056 0.71623 0.00097  -0.16323 -0.11516 181 ASP A N   
1326 C CA  . ASP A 181 ? 0.79851 0.87127 0.81084 0.01138  -0.17422 -0.13981 181 ASP A CA  
1327 C C   . ASP A 181 ? 0.69297 0.77683 0.64267 0.01990  -0.13772 -0.13811 181 ASP A C   
1328 O O   . ASP A 181 ? 0.78481 0.84880 0.66471 0.02917  -0.14179 -0.14427 181 ASP A O   
1329 C CB  . ASP A 181 ? 0.80077 0.85785 0.82862 0.01487  -0.18053 -0.15663 181 ASP A CB  
1330 C CG  . ASP A 181 ? 1.05753 1.07890 1.00054 0.03064  -0.18920 -0.18413 181 ASP A CG  
1331 O OD1 . ASP A 181 ? 1.20233 1.18420 1.11553 0.03716  -0.23284 -0.20189 181 ASP A OD1 
1332 O OD2 . ASP A 181 ? 1.03226 1.06220 0.93881 0.03912  -0.15357 -0.18826 181 ASP A OD2 
1333 N N   . ALA A 182 ? 0.66496 0.77792 0.64125 0.01905  -0.10255 -0.12790 182 ALA A N   
1334 C CA  . ALA A 182 ? 0.69704 0.82159 0.63606 0.02622  -0.07082 -0.12446 182 ALA A CA  
1335 C C   . ALA A 182 ? 0.70227 0.83799 0.63054 0.02341  -0.06928 -0.10766 182 ALA A C   
1336 O O   . ALA A 182 ? 0.73572 0.86541 0.61574 0.03078  -0.05662 -0.10491 182 ALA A O   
1337 C CB  . ALA A 182 ? 0.59146 0.73850 0.56880 0.02716  -0.04421 -0.11981 182 ALA A CB  
1338 N N   . MET A 183 ? 0.66212 0.81374 0.63749 0.01446  -0.07981 -0.09397 183 MET A N   
1339 C CA  . MET A 183 ? 0.62148 0.78389 0.59414 0.01126  -0.08148 -0.07838 183 MET A CA  
1340 C C   . MET A 183 ? 0.69668 0.83296 0.61970 0.01218  -0.10683 -0.08085 183 MET A C   
1341 O O   . MET A 183 ? 0.80581 0.94517 0.70612 0.01296  -0.10316 -0.06802 183 MET A O   
1342 C CB  . MET A 183 ? 0.56481 0.74731 0.59892 0.00484  -0.08696 -0.06495 183 MET A CB  
1343 C CG  . MET A 183 ? 0.44183 0.64336 0.50869 0.01074  -0.06283 -0.06122 183 MET A CG  
1344 S SD  . MET A 183 ? 0.55156 0.77254 0.67065 0.01251  -0.06232 -0.04354 183 MET A SD  
1345 C CE  . MET A 183 ? 0.54318 0.77511 0.64740 0.01509  -0.05797 -0.03740 183 MET A CE  
1346 N N   . GLU A 184 ? 0.64564 0.75240 0.55125 0.01397  -0.13591 -0.09703 184 GLU A N   
1347 C CA  . GLU A 184 ? 0.82248 0.89263 0.66463 0.02113  -0.16619 -0.10433 184 GLU A CA  
1348 C C   . GLU A 184 ? 0.85061 0.89437 0.60242 0.04042  -0.14939 -0.11557 184 GLU A C   
1349 O O   . GLU A 184 ? 0.90857 0.92848 0.59029 0.05213  -0.15463 -0.11136 184 GLU A O   
1350 C CB  . GLU A 184 ? 0.71626 0.75970 0.58625 0.01709  -0.21491 -0.11858 184 GLU A CB  
1351 N N   . ARG A 185 ? 0.77251 0.81806 0.52237 0.04658  -0.12748 -0.12815 185 ARG A N   
1352 C CA  . ARG A 185 ? 0.93774 0.96341 0.60940 0.06746  -0.10136 -0.13536 185 ARG A CA  
1353 C C   . ARG A 185 ? 0.88893 0.93696 0.54729 0.07114  -0.06064 -0.10956 185 ARG A C   
1354 O O   . ARG A 185 ? 0.99843 1.02334 0.57988 0.09033  -0.04582 -0.10409 185 ARG A O   
1355 C CB  . ARG A 185 ? 0.90214 0.93297 0.59250 0.07106  -0.08215 -0.15084 185 ARG A CB  
1356 C CG  . ARG A 185 ? 1.07516 1.07206 0.75799 0.07550  -0.11950 -0.17897 185 ARG A CG  
1357 C CD  . ARG A 185 ? 0.90326 0.90059 0.58728 0.08397  -0.09557 -0.19417 185 ARG A CD  
1358 N NE  . ARG A 185 ? 0.94353 0.97452 0.71746 0.06597  -0.08810 -0.18779 185 ARG A NE  
1359 C CZ  . ARG A 185 ? 0.89135 0.95506 0.69952 0.06239  -0.05052 -0.17556 185 ARG A CZ  
1360 N NH1 . ARG A 185 ? 0.75777 0.82990 0.53534 0.07259  -0.01535 -0.16724 185 ARG A NH1 
1361 N NH2 . ARG A 185 ? 0.80605 0.89199 0.68328 0.05039  -0.04898 -0.16985 185 ARG A NH2 
1362 N N   . HIS A 186 ? 0.73257 0.74066 0.61036 0.01550  -0.10538 -0.12006 186 HIS A N   
1363 C CA  . HIS A 186 ? 0.87576 0.86721 0.72179 0.01775  -0.09865 -0.09964 186 HIS A CA  
1364 C C   . HIS A 186 ? 0.91159 0.89776 0.73307 0.02765  -0.11496 -0.08664 186 HIS A C   
1365 O O   . HIS A 186 ? 0.79823 0.76645 0.58972 0.02926  -0.10921 -0.06953 186 HIS A O   
1366 C CB  . HIS A 186 ? 0.76171 0.74699 0.63412 0.01404  -0.08365 -0.08778 186 HIS A CB  
1367 C CG  . HIS A 186 ? 0.81981 0.80711 0.71287 0.00730  -0.06743 -0.09627 186 HIS A CG  
1368 N ND1 . HIS A 186 ? 0.88239 0.86346 0.75829 0.00333  -0.05242 -0.09466 186 HIS A ND1 
1369 C CD2 . HIS A 186 ? 0.81375 0.80751 0.74434 0.00460  -0.06331 -0.10610 186 HIS A CD2 
1370 C CE1 . HIS A 186 ? 0.83153 0.81691 0.73520 0.00029  -0.04147 -0.10359 186 HIS A CE1 
1371 N NE2 . HIS A 186 ? 0.80812 0.79878 0.74334 0.00122  -0.04774 -0.10949 186 HIS A NE2 
1372 N N   A HIS A 187 ? 0.86069 0.86177 0.69690 0.03438  -0.13437 -0.09486 187 HIS A N   
1373 N N   B HIS A 187 ? 0.86147 0.86248 0.69692 0.03445  -0.13451 -0.09487 187 HIS A N   
1374 C CA  A HIS A 187 ? 0.82480 0.82315 0.64254 0.04702  -0.15273 -0.08394 187 HIS A CA  
1375 C CA  B HIS A 187 ? 0.82516 0.82328 0.64255 0.04710  -0.15274 -0.08369 187 HIS A CA  
1376 C C   A HIS A 187 ? 0.78067 0.76267 0.60450 0.04963  -0.14547 -0.06347 187 HIS A C   
1377 C C   B HIS A 187 ? 0.78048 0.76215 0.60403 0.04950  -0.14513 -0.06328 187 HIS A C   
1378 O O   A HIS A 187 ? 0.84939 0.81203 0.63909 0.05649  -0.14794 -0.04678 187 HIS A O   
1379 O O   B HIS A 187 ? 0.85036 0.81230 0.63962 0.05600  -0.14693 -0.04645 187 HIS A O   
1380 C CB  A HIS A 187 ? 0.91502 0.90338 0.67503 0.05313  -0.16126 -0.07957 187 HIS A CB  
1381 C CB  B HIS A 187 ? 0.91592 0.90397 0.67562 0.05346  -0.16157 -0.07905 187 HIS A CB  
1382 C CG  A HIS A 187 ? 0.93439 0.94184 0.68534 0.05212  -0.17233 -0.10197 187 HIS A CG  
1383 C CG  B HIS A 187 ? 0.92797 0.92008 0.67190 0.06950  -0.18712 -0.07410 187 HIS A CG  
1384 N ND1 A HIS A 187 ? 0.94951 0.95204 0.66856 0.04475  -0.16133 -0.10953 187 HIS A ND1 
1385 N ND1 B HIS A 187 ? 0.93328 0.95387 0.70304 0.07557  -0.20845 -0.09237 187 HIS A ND1 
1386 C CD2 A HIS A 187 ? 0.93991 0.97319 0.71084 0.05688  -0.19305 -0.12076 187 HIS A CD2 
1387 C CD2 B HIS A 187 ? 0.89366 0.86479 0.60076 0.08158  -0.19492 -0.05311 187 HIS A CD2 
1388 C CE1 A HIS A 187 ? 0.92431 0.94751 0.64224 0.04500  -0.17495 -0.13221 187 HIS A CE1 
1389 C CE1 B HIS A 187 ? 0.89689 0.91697 0.64698 0.09225  -0.23014 -0.08319 187 HIS A CE1 
1390 N NE2 A HIS A 187 ? 0.88890 0.93170 0.63881 0.05199  -0.19479 -0.13968 187 HIS A NE2 
1391 N NE2 B HIS A 187 ? 0.93982 0.92769 0.65036 0.09684  -0.22232 -0.05821 187 HIS A NE2 
1392 N N   . VAL A 188 ? 0.64900 0.63736 0.51543 0.04388  -0.13584 -0.06505 188 VAL A N   
1393 C CA  . VAL A 188 ? 0.68255 0.65920 0.55910 0.04508  -0.12865 -0.04967 188 VAL A CA  
1394 C C   . VAL A 188 ? 0.79126 0.78331 0.70654 0.05029  -0.13861 -0.05450 188 VAL A C   
1395 O O   . VAL A 188 ? 0.62697 0.63974 0.57015 0.04897  -0.14562 -0.07042 188 VAL A O   
1396 C CB  . VAL A 188 ? 0.78436 0.75516 0.67328 0.03402  -0.10713 -0.04573 188 VAL A CB  
1397 C CG1 . VAL A 188 ? 0.66842 0.62354 0.52109 0.02917  -0.09517 -0.03917 188 VAL A CG1 
1398 C CG2 . VAL A 188 ? 0.60808 0.59489 0.53117 0.02714  -0.10182 -0.06012 188 VAL A CG2 
1399 N N   . GLN A 189 ? 0.70699 0.68861 0.62571 0.05510  -0.13723 -0.04198 189 GLN A N   
1400 C CA  . GLN A 189 ? 0.65837 0.65332 0.61415 0.05956  -0.14277 -0.04590 189 GLN A CA  
1401 C C   . GLN A 189 ? 0.58858 0.58073 0.56681 0.05122  -0.12547 -0.04136 189 GLN A C   
1402 O O   . GLN A 189 ? 0.64590 0.64766 0.65304 0.05349  -0.12635 -0.04414 189 GLN A O   
1403 C CB  . GLN A 189 ? 0.63226 0.61921 0.57615 0.07491  -0.15778 -0.03750 189 GLN A CB  
1404 C CG  . GLN A 189 ? 0.63025 0.61987 0.54674 0.08672  -0.17856 -0.03963 189 GLN A CG  
1405 C CD  . GLN A 189 ? 0.68505 0.70607 0.62679 0.08550  -0.19069 -0.06107 189 GLN A CD  
1406 O OE1 . GLN A 189 ? 0.81800 0.84358 0.73741 0.08397  -0.19691 -0.06851 189 GLN A OE1 
1407 N NE2 . GLN A 189 ? 0.72325 0.76647 0.71269 0.08468  -0.19235 -0.07278 189 GLN A NE2 
1408 N N   . TRP A 190 ? 0.57812 0.55936 0.54372 0.04209  -0.11008 -0.03542 190 TRP A N   
1409 C CA  . TRP A 190 ? 0.62325 0.60350 0.60547 0.03482  -0.09524 -0.03115 190 TRP A CA  
1410 C C   . TRP A 190 ? 0.71403 0.69793 0.69975 0.02571  -0.08383 -0.03460 190 TRP A C   
1411 O O   . TRP A 190 ? 0.72486 0.70268 0.68886 0.02369  -0.08157 -0.03483 190 TRP A O   
1412 C CB  . TRP A 190 ? 0.74821 0.70959 0.71091 0.03509  -0.08866 -0.01862 190 TRP A CB  
1413 C CG  . TRP A 190 ? 0.79827 0.75344 0.76480 0.04435  -0.09657 -0.01480 190 TRP A CG  
1414 C CD1 . TRP A 190 ? 0.76090 0.70263 0.70620 0.05525  -0.10847 -0.00905 190 TRP A CD1 
1415 C CD2 . TRP A 190 ? 0.75728 0.71849 0.74978 0.04474  -0.09289 -0.01656 190 TRP A CD2 
1416 N NE1 . TRP A 190 ? 0.74008 0.67871 0.70010 0.06339  -0.11276 -0.00740 190 TRP A NE1 
1417 C CE2 . TRP A 190 ? 0.86864 0.82003 0.85824 0.05639  -0.10262 -0.01315 190 TRP A CE2 
1418 C CE3 . TRP A 190 ? 0.63092 0.60420 0.64672 0.03708  -0.08214 -0.02044 190 TRP A CE3 
1419 C CZ2 . TRP A 190 ? 0.78795 0.74262 0.80089 0.05993  -0.10079 -0.01587 190 TRP A CZ2 
1420 C CZ3 . TRP A 190 ? 0.85549 0.83233 0.89004 0.03950  -0.08007 -0.02253 190 TRP A CZ3 
1421 C CH2 . TRP A 190 ? 0.79403 0.76223 0.82882 0.05052  -0.08880 -0.02139 190 TRP A CH2 
1422 N N   . LEU A 191 ? 0.55736 0.55027 0.56951 0.02094  -0.07610 -0.03704 191 LEU A N   
1423 C CA  . LEU A 191 ? 0.61624 0.61070 0.63450 0.01479  -0.06558 -0.03855 191 LEU A CA  
1424 C C   . LEU A 191 ? 0.55002 0.54584 0.57984 0.01184  -0.05575 -0.03147 191 LEU A C   
1425 O O   . LEU A 191 ? 0.53885 0.53958 0.58353 0.01230  -0.05588 -0.03092 191 LEU A O   
1426 C CB  . LEU A 191 ? 0.53461 0.53736 0.57264 0.01265  -0.06733 -0.05027 191 LEU A CB  
1427 C CG  . LEU A 191 ? 0.66556 0.66787 0.72052 0.00775  -0.05577 -0.05094 191 LEU A CG  
1428 C CD1 . LEU A 191 ? 0.44820 0.44453 0.49007 0.00697  -0.04907 -0.05010 191 LEU A CD1 
1429 C CD2 . LEU A 191 ? 0.52211 0.53010 0.60103 0.00444  -0.05690 -0.06304 191 LEU A CD2 
1430 N N   . ILE A 192 ? 0.57430 0.56785 0.59711 0.00919  -0.04751 -0.02716 192 ILE A N   
1431 C CA  . ILE A 192 ? 0.57153 0.56911 0.60231 0.00740  -0.04002 -0.02104 192 ILE A CA  
1432 C C   . ILE A 192 ? 0.61767 0.61753 0.65756 0.00712  -0.03414 -0.02142 192 ILE A C   
1433 O O   . ILE A 192 ? 0.49676 0.49479 0.53057 0.00723  -0.03256 -0.02508 192 ILE A O   
1434 C CB  . ILE A 192 ? 0.45592 0.45131 0.47243 0.00561  -0.03687 -0.01628 192 ILE A CB  
1435 C CG1 . ILE A 192 ? 0.43870 0.42526 0.44389 0.00699  -0.04191 -0.01507 192 ILE A CG1 
1436 C CG2 . ILE A 192 ? 0.50444 0.50822 0.52899 0.00411  -0.03168 -0.01229 192 ILE A CG2 
1437 C CD1 . ILE A 192 ? 0.41507 0.39447 0.40539 0.00311  -0.03641 -0.01137 192 ILE A CD1 
1438 N N   . HIS A 193 ? 0.47165 0.47405 0.52497 0.00732  -0.03009 -0.01740 193 HIS A N   
1439 C CA  . HIS A 193 ? 0.40331 0.40405 0.46483 0.00933  -0.02461 -0.01507 193 HIS A CA  
1440 C C   . HIS A 193 ? 0.50951 0.51258 0.57508 0.01068  -0.02048 -0.00555 193 HIS A C   
1441 O O   . HIS A 193 ? 0.45655 0.46380 0.51941 0.00870  -0.02085 -0.00303 193 HIS A O   
1442 C CB  . HIS A 193 ? 0.47292 0.46660 0.54633 0.00831  -0.02375 -0.02260 193 HIS A CB  
1443 C CG  . HIS A 193 ? 0.57703 0.56874 0.66489 0.00501  -0.02186 -0.02328 193 HIS A CG  
1444 N ND1 . HIS A 193 ? 0.61901 0.60495 0.71555 0.00480  -0.01376 -0.01528 193 HIS A ND1 
1445 C CD2 . HIS A 193 ? 0.54143 0.53698 0.63740 0.00172  -0.02637 -0.03153 193 HIS A CD2 
1446 C CE1 . HIS A 193 ? 0.60766 0.59328 0.71748 -0.00047 -0.01101 -0.01909 193 HIS A CE1 
1447 N NE2 . HIS A 193 ? 0.52017 0.51378 0.63255 -0.00214 -0.01923 -0.03007 193 HIS A NE2 
1448 N N   . GLY A 194 ? 0.47547 0.47511 0.54617 0.01496  -0.01642 -0.00027 194 GLY A N   
1449 C CA  . GLY A 194 ? 0.53307 0.53192 0.60324 0.01773  -0.01271 0.01081  194 GLY A CA  
1450 C C   . GLY A 194 ? 0.56280 0.54593 0.64340 0.01930  -0.00602 0.01503  194 GLY A C   
1451 O O   . GLY A 194 ? 0.58636 0.56141 0.67747 0.01345  -0.00266 0.00878  194 GLY A O   
1452 N N   . HIS A 195 ? 0.59095 0.56968 0.66988 0.02752  -0.00419 0.02527  195 HIS A N   
1453 C CA  . HIS A 195 ? 0.50928 0.46773 0.59675 0.03128  0.00315  0.03188  195 HIS A CA  
1454 C C   . HIS A 195 ? 0.55647 0.50110 0.64317 0.02579  0.01234  0.04012  195 HIS A C   
1455 O O   . HIS A 195 ? 0.53456 0.46409 0.61606 0.03163  0.01810  0.05456  195 HIS A O   
1456 C CB  . HIS A 195 ? 0.37652 0.32511 0.47952 0.02884  0.00545  0.01898  195 HIS A CB  
1457 C CG  . HIS A 195 ? 0.54627 0.47028 0.66069 0.03103  0.01491  0.02401  195 HIS A CG  
1458 N ND1 . HIS A 195 ? 0.53905 0.45199 0.65309 0.04342  0.01663  0.03600  195 HIS A ND1 
1459 C CD2 . HIS A 195 ? 0.52545 0.43265 0.65334 0.02249  0.02369  0.01861  195 HIS A CD2 
1460 C CE1 . HIS A 195 ? 0.51734 0.40339 0.64217 0.04267  0.02700  0.03924  195 HIS A CE1 
1461 N NE2 . HIS A 195 ? 0.57115 0.45368 0.70532 0.02874  0.03223  0.02793  195 HIS A NE2 
1462 N N   . THR A 196 ? 0.54257 0.49132 0.63490 0.01509  0.01456  0.03136  196 THR A N   
1463 C CA  . THR A 196 ? 0.53907 0.47632 0.63475 0.00794  0.02615  0.03674  196 THR A CA  
1464 C C   . THR A 196 ? 0.69876 0.64174 0.77481 0.00910  0.02873  0.04950  196 THR A C   
1465 O O   . THR A 196 ? 0.54265 0.47290 0.61618 0.00429  0.04103  0.05780  196 THR A O   
1466 C CB  . THR A 196 ? 0.64911 0.59309 0.76250 -0.00329 0.02754  0.02080  196 THR A CB  
1467 O OG1 . THR A 196 ? 0.56223 0.52699 0.66937 -0.00372 0.01835  0.01447  196 THR A OG1 
1468 C CG2 . THR A 196 ? 0.51162 0.45016 0.64288 -0.00551 0.02531  0.00659  196 THR A CG2 
1469 N N   . HIS A 197 ? 0.59460 0.55607 0.65638 0.01411  0.01886  0.05012  197 HIS A N   
1470 C CA  . HIS A 197 ? 0.62638 0.59615 0.66778 0.01520  0.02013  0.05944  197 HIS A CA  
1471 C C   . HIS A 197 ? 0.62333 0.59748 0.66791 0.00444  0.02846  0.05343  197 HIS A C   
1472 O O   . HIS A 197 ? 0.57176 0.54606 0.60035 0.00276  0.03584  0.06175  197 HIS A O   
1473 C CB  . HIS A 197 ? 0.63452 0.58893 0.65930 0.02300  0.02541  0.07888  197 HIS A CB  
1474 C CG  . HIS A 197 ? 0.60708 0.55967 0.63056 0.03646  0.01651  0.08529  197 HIS A CG  
1475 N ND1 . HIS A 197 ? 0.75448 0.69394 0.76273 0.04782  0.01749  0.10384  197 HIS A ND1 
1476 C CD2 . HIS A 197 ? 0.51479 0.47768 0.55060 0.04113  0.00695  0.07553  197 HIS A CD2 
1477 C CE1 . HIS A 197 ? 0.57050 0.51414 0.58571 0.05994  0.00787  0.10408  197 HIS A CE1 
1478 N NE2 . HIS A 197 ? 0.65122 0.60975 0.68353 0.05511  0.00245  0.08631  197 HIS A NE2 
1479 N N   . ARG A 198 ? 0.51284 0.49185 0.57783 -0.00225 0.02731  0.03842  198 ARG A N   
1480 C CA  . ARG A 198 ? 0.50715 0.49332 0.58277 -0.01119 0.03440  0.02979  198 ARG A CA  
1481 C C   . ARG A 198 ? 0.52737 0.53066 0.60685 -0.01035 0.02342  0.01724  198 ARG A C   
1482 O O   . ARG A 198 ? 0.55530 0.56216 0.65277 -0.01213 0.01820  0.00535  198 ARG A O   
1483 C CB  . ARG A 198 ? 0.55291 0.53006 0.65386 -0.01908 0.04269  0.02226  198 ARG A CB  
1484 C CG  . ARG A 198 ? 0.51143 0.46760 0.61039 -0.02354 0.05933  0.03436  198 ARG A CG  
1485 C CD  . ARG A 198 ? 0.66466 0.61150 0.79294 -0.03220 0.06636  0.02357  198 ARG A CD  
1486 N NE  . ARG A 198 ? 0.90823 0.82843 1.03524 -0.03667 0.08345  0.03584  198 ARG A NE  
1487 C CZ  . ARG A 198 ? 1.08331 0.98174 1.21439 -0.03359 0.08503  0.04031  198 ARG A CZ  
1488 N NH1 . ARG A 198 ? 1.06791 0.97019 1.20360 -0.02606 0.07080  0.03300  198 ARG A NH1 
1489 N NH2 . ARG A 198 ? 1.05040 0.92061 1.17996 -0.03817 0.10274  0.05261  198 ARG A NH2 
1490 N N   . PRO A 199 ? 0.61417 0.62740 0.67655 -0.00743 0.01954  0.01929  199 PRO A N   
1491 C CA  . PRO A 199 ? 0.61666 0.64065 0.68173 -0.00646 0.01037  0.00861  199 PRO A CA  
1492 C C   . PRO A 199 ? 0.60371 0.63343 0.68733 -0.01072 0.01338  -0.00278 199 PRO A C   
1493 O O   . PRO A 199 ? 0.60840 0.64221 0.69478 -0.01528 0.02395  -0.00381 199 PRO A O   
1494 C CB  . PRO A 199 ? 0.62258 0.65523 0.66734 -0.00472 0.00927  0.01212  199 PRO A CB  
1495 C CG  . PRO A 199 ? 0.51514 0.54505 0.54697 -0.00585 0.01928  0.02267  199 PRO A CG  
1496 C CD  . PRO A 199 ? 0.56192 0.57649 0.60095 -0.00504 0.02346  0.03084  199 PRO A CD  
1497 N N   . ALA A 200 ? 0.50284 0.53378 0.59893 -0.00852 0.00398  -0.01161 200 ALA A N   
1498 C CA  . ALA A 200 ? 0.63753 0.67581 0.75615 -0.00986 0.00340  -0.02332 200 ALA A CA  
1499 C C   . ALA A 200 ? 0.61640 0.65425 0.73674 -0.00379 -0.01100 -0.02920 200 ALA A C   
1500 O O   . ALA A 200 ? 0.56600 0.59653 0.67183 -0.00104 -0.01746 -0.02457 200 ALA A O   
1501 C CB  . ALA A 200 ? 0.37477 0.41265 0.51394 -0.01579 0.01107  -0.02666 200 ALA A CB  
1502 N N   . VAL A 201 ? 0.49962 0.54548 0.63716 -0.00108 -0.01556 -0.03925 201 VAL A N   
1503 C CA  . VAL A 201 ? 0.50299 0.54795 0.64287 0.00605  -0.03021 -0.04434 201 VAL A CA  
1504 C C   . VAL A 201 ? 0.63325 0.69070 0.80164 0.00545  -0.03346 -0.05601 201 VAL A C   
1505 O O   . VAL A 201 ? 0.51529 0.58526 0.70660 0.00340  -0.02728 -0.06397 201 VAL A O   
1506 C CB  . VAL A 201 ? 0.46589 0.50831 0.60046 0.01298  -0.03580 -0.04565 201 VAL A CB  
1507 C CG1 . VAL A 201 ? 0.56397 0.60708 0.70549 0.02219  -0.05090 -0.05116 201 VAL A CG1 
1508 C CG2 . VAL A 201 ? 0.53954 0.56940 0.64734 0.01248  -0.03464 -0.03675 201 VAL A CG2 
1509 N N   . HIS A 202 ? 0.54734 0.60351 0.71591 0.00630  -0.04218 -0.05901 202 HIS A N   
1510 C CA  . HIS A 202 ? 0.58384 0.65427 0.78056 0.00447  -0.04662 -0.07282 202 HIS A CA  
1511 C C   . HIS A 202 ? 0.50068 0.57642 0.69516 0.01509  -0.06642 -0.07911 202 HIS A C   
1512 O O   . HIS A 202 ? 0.69377 0.75690 0.86069 0.01971  -0.07438 -0.07213 202 HIS A O   
1513 C CB  . HIS A 202 ? 0.52549 0.59062 0.72547 -0.00401 -0.04040 -0.07401 202 HIS A CB  
1514 C CG  . HIS A 202 ? 0.57036 0.62533 0.76717 -0.01239 -0.02196 -0.06437 202 HIS A CG  
1515 N ND1 . HIS A 202 ? 0.48723 0.54770 0.70718 -0.02151 -0.00761 -0.06883 202 HIS A ND1 
1516 C CD2 . HIS A 202 ? 0.54314 0.58301 0.71533 -0.01234 -0.01574 -0.05003 202 HIS A CD2 
1517 C CE1 . HIS A 202 ? 0.53568 0.58161 0.74088 -0.02605 0.00648  -0.05552 202 HIS A CE1 
1518 N NE2 . HIS A 202 ? 0.59255 0.62742 0.76994 -0.01970 0.00046  -0.04440 202 HIS A NE2 
1519 N N   . GLU A 203 ? 0.59392 0.68895 0.81683 0.01928  -0.07410 -0.09226 203 GLU A N   
1520 C CA  . GLU A 203 ? 0.61756 0.72087 0.84034 0.03124  -0.09541 -0.09906 203 GLU A CA  
1521 C C   . GLU A 203 ? 0.53070 0.65005 0.77281 0.02639  -0.10213 -0.11436 203 GLU A C   
1522 O O   . GLU A 203 ? 0.60936 0.74117 0.88229 0.01523  -0.09080 -0.12497 203 GLU A O   
1523 C CB  . GLU A 203 ? 0.57259 0.68999 0.81750 0.04194  -0.10262 -0.10548 203 GLU A CB  
1524 C CG  . GLU A 203 ? 0.64630 0.76622 0.88239 0.05886  -0.12635 -0.10682 203 GLU A CG  
1525 C CD  . GLU A 203 ? 0.95575 1.08533 1.21343 0.07202  -0.13260 -0.11101 203 GLU A CD  
1526 O OE1 . GLU A 203 ? 0.88429 1.02343 1.14676 0.08772  -0.15371 -0.11575 203 GLU A OE1 
1527 O OE2 . GLU A 203 ? 0.95577 1.08352 1.22501 0.06761  -0.11670 -0.10994 203 GLU A OE2 
1528 N N   . LEU A 204 ? 0.57222 0.69024 0.79478 0.03374  -0.11934 -0.11603 204 LEU A N   
1529 C CA  . LEU A 204 ? 0.44385 0.57815 0.68140 0.02962  -0.12815 -0.13309 204 LEU A CA  
1530 C C   . LEU A 204 ? 0.51166 0.65177 0.72916 0.04462  -0.15337 -0.13565 204 LEU A C   
1531 O O   . LEU A 204 ? 0.62955 0.76154 0.82888 0.05826  -0.16273 -0.12453 204 LEU A O   
1532 C CB  . LEU A 204 ? 0.47328 0.59187 0.69789 0.01708  -0.11500 -0.13079 204 LEU A CB  
1533 C CG  . LEU A 204 ? 0.47723 0.57268 0.65598 0.02138  -0.11713 -0.11633 204 LEU A CG  
1534 C CD1 . LEU A 204 ? 0.56677 0.66035 0.73869 0.01489  -0.11767 -0.12617 204 LEU A CD1 
1535 C CD2 . LEU A 204 ? 0.51998 0.59463 0.68245 0.01802  -0.10026 -0.09798 204 LEU A CD2 
1536 N N   . GLN A 205 ? 0.63972 0.79226 0.85852 0.04232  -0.16423 -0.15027 205 GLN A N   
1537 C CA  . GLN A 205 ? 0.68815 0.84572 0.88039 0.05620  -0.18865 -0.15243 205 GLN A CA  
1538 C C   . GLN A 205 ? 0.60073 0.74539 0.76096 0.04945  -0.18684 -0.15325 205 GLN A C   
1539 O O   . GLN A 205 ? 0.64167 0.79079 0.82072 0.03531  -0.17592 -0.16611 205 GLN A O   
1540 C CB  . GLN A 205 ? 0.49149 0.68649 0.71958 0.06274  -0.20913 -0.17518 205 GLN A CB  
1541 N N   . ALA A 206 ? 0.54780 0.67453 0.65992 0.05917  -0.19559 -0.13962 206 ALA A N   
1542 C CA  . ALA A 206 ? 0.69977 0.81490 0.77766 0.05402  -0.19366 -0.14083 206 ALA A CA  
1543 C C   . ALA A 206 ? 0.69701 0.80697 0.72915 0.06884  -0.21369 -0.13387 206 ALA A C   
1544 O O   . ALA A 206 ? 0.81249 0.90627 0.82257 0.08030  -0.21749 -0.11512 206 ALA A O   
1545 C CB  . ALA A 206 ? 0.71981 0.80737 0.78019 0.04469  -0.17020 -0.12514 206 ALA A CB  
1546 N N   . ASN A 207 ? 0.60729 0.72890 0.62326 0.06826  -0.22545 -0.14895 207 ASN A N   
1547 C CA  . ASN A 207 ? 0.96292 1.08186 0.93095 0.08266  -0.24630 -0.14386 207 ASN A CA  
1548 C C   . ASN A 207 ? 0.86242 0.99817 0.84150 0.10133  -0.27091 -0.14299 207 ASN A C   
1549 O O   . ASN A 207 ? 0.93158 1.05194 0.86993 0.11741  -0.28395 -0.12577 207 ASN A O   
1550 C CB  . ASN A 207 ? 0.83319 0.91552 0.74751 0.08453  -0.23464 -0.11866 207 ASN A CB  
1551 C CG  . ASN A 207 ? 0.86620 0.93287 0.77986 0.06771  -0.20804 -0.11721 207 ASN A CG  
1552 O OD1 . ASN A 207 ? 0.84998 0.92445 0.76443 0.05809  -0.20352 -0.13366 207 ASN A OD1 
1553 N ND2 . ASN A 207 ? 0.83977 0.88533 0.75430 0.06462  -0.19064 -0.09892 207 ASN A ND2 
1554 N N   . GLY A 208 ? 0.74850 0.91516 0.78406 0.09950  -0.27637 -0.16158 208 GLY A N   
1555 C CA  . GLY A 208 ? 0.66204 0.85075 0.71821 0.11767  -0.29974 -0.16473 208 GLY A CA  
1556 C C   . GLY A 208 ? 0.84498 1.01285 0.90041 0.12918  -0.29519 -0.14199 208 GLY A C   
1557 O O   . GLY A 208 ? 1.05784 1.23713 1.12004 0.14879  -0.31623 -0.14030 208 GLY A O   
1558 N N   . GLN A 209 ? 0.84686 0.98591 0.89646 0.11834  -0.26913 -0.12599 209 GLN A N   
1559 C CA  . GLN A 209 ? 0.72688 0.84357 0.77361 0.12700  -0.26237 -0.10594 209 GLN A CA  
1560 C C   . GLN A 209 ? 0.75739 0.87127 0.83885 0.11070  -0.23600 -0.10659 209 GLN A C   
1561 O O   . GLN A 209 ? 0.74884 0.86623 0.84110 0.09331  -0.22073 -0.11495 209 GLN A O   
1562 C CB  . GLN A 209 ? 0.82517 0.90147 0.81075 0.13225  -0.25849 -0.08076 209 GLN A CB  
1563 N N   . PRO A 210 ? 0.80300 0.91006 0.90160 0.11677  -0.23045 -0.09818 210 PRO A N   
1564 C CA  . PRO A 210 ? 0.74610 0.84679 0.86720 0.10186  -0.20485 -0.09594 210 PRO A CA  
1565 C C   . PRO A 210 ? 0.71976 0.79295 0.80651 0.08903  -0.18644 -0.08257 210 PRO A C   
1566 O O   . PRO A 210 ? 0.69209 0.74043 0.73589 0.09403  -0.18834 -0.06761 210 PRO A O   
1567 C CB  . PRO A 210 ? 0.64824 0.73953 0.77814 0.11394  -0.20478 -0.08671 210 PRO A CB  
1568 C CG  . PRO A 210 ? 0.57844 0.68596 0.71557 0.13507  -0.23196 -0.09248 210 PRO A CG  
1569 C CD  . PRO A 210 ? 0.68901 0.79476 0.78839 0.13853  -0.24783 -0.09168 210 PRO A CD  
1570 N N   . ALA A 211 ? 0.62428 0.70188 0.73113 0.07271  -0.16785 -0.08786 211 ALA A N   
1571 C CA  . ALA A 211 ? 0.54667 0.60342 0.62982 0.06122  -0.15025 -0.07733 211 ALA A CA  
1572 C C   . ALA A 211 ? 0.62691 0.68283 0.73292 0.05134  -0.13081 -0.07473 211 ALA A C   
1573 O O   . ALA A 211 ? 0.57547 0.64856 0.71684 0.04982  -0.12844 -0.08391 211 ALA A O   
1574 C CB  . ALA A 211 ? 0.60342 0.66499 0.68038 0.05246  -0.14928 -0.08686 211 ALA A CB  
1575 N N   . TRP A 212 ? 0.54231 0.57959 0.62731 0.04463  -0.11672 -0.06270 212 TRP A N   
1576 C CA  . TRP A 212 ? 0.46576 0.50142 0.56466 0.03659  -0.09983 -0.05851 212 TRP A CA  
1577 C C   . TRP A 212 ? 0.61146 0.63905 0.69967 0.02682  -0.08721 -0.05403 212 TRP A C   
1578 O O   . TRP A 212 ? 0.57067 0.58731 0.63320 0.02690  -0.08818 -0.04939 212 TRP A O   
1579 C CB  . TRP A 212 ? 0.74850 0.77147 0.83638 0.04123  -0.09656 -0.04829 212 TRP A CB  
1580 C CG  . TRP A 212 ? 0.61612 0.64638 0.72050 0.05205  -0.10675 -0.05297 212 TRP A CG  
1581 C CD1 . TRP A 212 ? 0.61389 0.65829 0.74947 0.05181  -0.10176 -0.06037 212 TRP A CD1 
1582 C CD2 . TRP A 212 ? 0.64591 0.67003 0.73682 0.06601  -0.12374 -0.05075 212 TRP A CD2 
1583 N NE1 . TRP A 212 ? 0.74248 0.79195 0.88943 0.06540  -0.11495 -0.06450 212 TRP A NE1 
1584 C CE2 . TRP A 212 ? 0.71664 0.75274 0.83552 0.07526  -0.12962 -0.05757 212 TRP A CE2 
1585 C CE3 . TRP A 212 ? 0.63367 0.64258 0.68977 0.07218  -0.13404 -0.04309 212 TRP A CE3 
1586 C CZ2 . TRP A 212 ? 0.77761 0.81053 0.89225 0.09249  -0.14744 -0.05617 212 TRP A CZ2 
1587 C CZ3 . TRP A 212 ? 0.82266 0.82642 0.86955 0.08830  -0.15111 -0.04016 212 TRP A CZ3 
1588 C CH2 . TRP A 212 ? 0.70820 0.72375 0.78499 0.09931  -0.15869 -0.04629 212 TRP A CH2 
1589 N N   . ARG A 213 ? 0.57139 0.60423 0.67941 0.01903  -0.07485 -0.05532 213 ARG A N   
1590 C CA  . ARG A 213 ? 0.46297 0.48796 0.56423 0.01218  -0.06289 -0.04948 213 ARG A CA  
1591 C C   . ARG A 213 ? 0.59466 0.61724 0.69543 0.00976  -0.05198 -0.04050 213 ARG A C   
1592 O O   . ARG A 213 ? 0.60241 0.63263 0.72137 0.00741  -0.04653 -0.04298 213 ARG A O   
1593 C CB  . ARG A 213 ? 0.57090 0.60078 0.69311 0.00569  -0.05785 -0.05803 213 ARG A CB  
1594 C CG  . ARG A 213 ? 0.56138 0.58069 0.67864 0.00115  -0.04572 -0.05073 213 ARG A CG  
1595 C CD  . ARG A 213 ? 0.64631 0.66438 0.78221 -0.00471 -0.04072 -0.05961 213 ARG A CD  
1596 N NE  . ARG A 213 ? 0.57094 0.59641 0.73404 -0.01069 -0.03465 -0.06559 213 ARG A NE  
1597 C CZ  . ARG A 213 ? 0.56438 0.58321 0.73525 -0.01582 -0.02019 -0.05784 213 ARG A CZ  
1598 N NH1 . ARG A 213 ? 0.52936 0.53596 0.68270 -0.01367 -0.01308 -0.04323 213 ARG A NH1 
1599 N NH2 . ARG A 213 ? 0.47563 0.50106 0.67225 -0.02324 -0.01252 -0.06520 213 ARG A NH2 
1600 N N   . VAL A 214 ? 0.56923 0.58328 0.64965 0.00974  -0.04842 -0.03167 214 VAL A N   
1601 C CA  . VAL A 214 ? 0.43797 0.45208 0.51459 0.00772  -0.04024 -0.02478 214 VAL A CA  
1602 C C   . VAL A 214 ? 0.56106 0.57386 0.63516 0.00470  -0.03242 -0.01902 214 VAL A C   
1603 O O   . VAL A 214 ? 0.45386 0.46242 0.51952 0.00544  -0.03346 -0.01794 214 VAL A O   
1604 C CB  . VAL A 214 ? 0.62015 0.62775 0.67897 0.00982  -0.04263 -0.02109 214 VAL A CB  
1605 C CG1 . VAL A 214 ? 0.45147 0.46251 0.50832 0.00676  -0.03492 -0.01762 214 VAL A CG1 
1606 C CG2 . VAL A 214 ? 0.48783 0.49226 0.54804 0.01558  -0.05137 -0.02490 214 VAL A CG2 
1607 N N   . VAL A 215 ? 0.52381 0.53988 0.60469 0.00213  -0.02432 -0.01526 215 VAL A N   
1608 C CA  . VAL A 215 ? 0.52964 0.54232 0.60830 0.00155  -0.01759 -0.00775 215 VAL A CA  
1609 C C   . VAL A 215 ? 0.61937 0.63694 0.68475 0.00240  -0.01478 -0.00049 215 VAL A C   
1610 O O   . VAL A 215 ? 0.47877 0.50179 0.54288 0.00049  -0.01223 -0.00153 215 VAL A O   
1611 C CB  . VAL A 215 ? 0.54985 0.55911 0.64375 -0.00227 -0.00944 -0.00765 215 VAL A CB  
1612 C CG1 . VAL A 215 ? 0.46937 0.46869 0.55945 -0.00063 -0.00336 0.00177  215 VAL A CG1 
1613 C CG2 . VAL A 215 ? 0.46178 0.47207 0.57334 -0.00458 -0.01343 -0.01946 215 VAL A CG2 
1614 N N   . LEU A 216 ? 0.57213 0.58995 0.62922 0.00555  -0.01557 0.00494  216 LEU A N   
1615 C CA  . LEU A 216 ? 0.42755 0.45432 0.47317 0.00704  -0.01532 0.00999  216 LEU A CA  
1616 C C   . LEU A 216 ? 0.55241 0.57814 0.59386 0.00868  -0.00948 0.01958  216 LEU A C   
1617 O O   . LEU A 216 ? 0.53893 0.55349 0.58709 0.00893  -0.00423 0.02411  216 LEU A O   
1618 C CB  . LEU A 216 ? 0.44473 0.47628 0.48692 0.01057  -0.01932 0.01034  216 LEU A CB  
1619 C CG  . LEU A 216 ? 0.58071 0.61406 0.61997 0.00733  -0.02249 0.00264  216 LEU A CG  
1620 C CD1 . LEU A 216 ? 0.64234 0.67641 0.68336 0.00951  -0.02329 0.00085  216 LEU A CD1 
1621 C CD2 . LEU A 216 ? 0.52869 0.57249 0.56118 0.00416  -0.02280 0.00020  216 LEU A CD2 
1622 N N   . GLY A 217 ? 0.43449 0.47096 0.46309 0.00941  -0.00989 0.02253  217 GLY A N   
1623 C CA  . GLY A 217 ? 0.45659 0.49240 0.47335 0.01253  -0.00559 0.03378  217 GLY A CA  
1624 C C   . GLY A 217 ? 0.68433 0.72558 0.69350 0.02171  -0.01179 0.04199  217 GLY A C   
1625 O O   . GLY A 217 ? 0.54690 0.60013 0.55948 0.02390  -0.01916 0.03614  217 GLY A O   
1626 N N   . ALA A 218 ? 0.53787 0.56968 0.53753 0.02737  -0.00803 0.05585  218 ALA A N   
1627 C CA  . ALA A 218 ? 0.55527 0.59277 0.54555 0.03920  -0.01513 0.06600  218 ALA A CA  
1628 C C   . ALA A 218 ? 0.57622 0.63461 0.54671 0.04073  -0.02093 0.06625  218 ALA A C   
1629 O O   . ALA A 218 ? 0.70315 0.76388 0.66189 0.03334  -0.01526 0.06378  218 ALA A O   
1630 C CB  . ALA A 218 ? 0.51404 0.52835 0.49846 0.04605  -0.00853 0.08315  218 ALA A CB  
1631 N N   . TRP A 219 ? 0.43193 0.50771 0.40030 0.05055  -0.03235 0.06745  219 TRP A N   
1632 C CA  . TRP A 219 ? 0.63603 0.73678 0.58700 0.05275  -0.04071 0.06501  219 TRP A CA  
1633 C C   . TRP A 219 ? 0.56349 0.65731 0.48819 0.06381  -0.04174 0.08452  219 TRP A C   
1634 O O   . TRP A 219 ? 0.73882 0.83862 0.65988 0.07861  -0.05191 0.09424  219 TRP A O   
1635 C CB  . TRP A 219 ? 0.50651 0.63397 0.47188 0.05694  -0.05302 0.05382  219 TRP A CB  
1636 C CG  . TRP A 219 ? 0.50528 0.63777 0.49052 0.04471  -0.05020 0.03579  219 TRP A CG  
1637 C CD1 . TRP A 219 ? 0.47829 0.59087 0.47630 0.03768  -0.04191 0.03250  219 TRP A CD1 
1638 C CD2 . TRP A 219 ? 0.49078 0.64870 0.48357 0.03814  -0.05548 0.01904  219 TRP A CD2 
1639 N NE1 . TRP A 219 ? 0.51681 0.63808 0.52591 0.02840  -0.04169 0.01743  219 TRP A NE1 
1640 C CE2 . TRP A 219 ? 0.38239 0.52988 0.38983 0.02756  -0.04855 0.00886  219 TRP A CE2 
1641 C CE3 . TRP A 219 ? 0.47704 0.66564 0.46558 0.03984  -0.06536 0.01102  219 TRP A CE3 
1642 C CZ2 . TRP A 219 ? 0.42387 0.58586 0.44099 0.01790  -0.04874 -0.00718 219 TRP A CZ2 
1643 C CZ3 . TRP A 219 ? 0.49425 0.70100 0.49686 0.02890  -0.06587 -0.00818 219 TRP A CZ3 
1644 C CH2 . TRP A 219 ? 0.36193 0.55292 0.37825 0.01771  -0.05638 -0.01615 219 TRP A CH2 
1645 N N   . HIS A 220 ? 0.67323 0.75318 0.57907 0.05709  -0.03032 0.09084  220 HIS A N   
1646 C CA  . HIS A 220 ? 0.66839 0.73614 0.54351 0.06577  -0.02772 0.11158  220 HIS A CA  
1647 C C   . HIS A 220 ? 0.72233 0.81404 0.56774 0.06567  -0.03366 0.10864  220 HIS A C   
1648 O O   . HIS A 220 ? 0.92231 1.03141 0.75155 0.07885  -0.04828 0.11482  220 HIS A O   
1649 C CB  . HIS A 220 ? 0.82262 0.85848 0.69451 0.05740  -0.00827 0.12115  220 HIS A CB  
1650 C CG  . HIS A 220 ? 1.01570 1.02926 0.85743 0.06632  -0.00228 0.14606  220 HIS A CG  
1651 N ND1 . HIS A 220 ? 1.02950 1.03233 0.84362 0.05867  0.01243  0.15420  220 HIS A ND1 
1652 C CD2 . HIS A 220 ? 0.96144 0.95935 0.79501 0.08275  -0.00802 0.16544  220 HIS A CD2 
1653 C CE1 . HIS A 220 ? 0.96088 0.94021 0.74796 0.06921  0.01614  0.17909  220 HIS A CE1 
1654 N NE2 . HIS A 220 ? 1.04854 1.02362 0.84717 0.08488  0.00309  0.18681  220 HIS A NE2 
1655 N N   . SER A 221 ? 0.83867 0.93317 0.67761 0.05153  -0.02299 0.09777  221 SER A N   
1656 C CA  . SER A 221 ? 0.76143 0.88028 0.57435 0.04900  -0.02729 0.08965  221 SER A CA  
1657 C C   . SER A 221 ? 0.79285 0.93638 0.62647 0.03926  -0.03277 0.06335  221 SER A C   
1658 O O   . SER A 221 ? 0.90482 1.07524 0.72411 0.03925  -0.04206 0.05262  221 SER A O   
1659 C CB  . SER A 221 ? 0.85773 0.96276 0.64546 0.04012  -0.00925 0.09496  221 SER A CB  
1660 O OG  . SER A 221 ? 1.05030 1.12551 0.82261 0.04582  0.00063  0.11940  221 SER A OG  
1661 N N   . GLU A 222 ? 0.67074 0.80481 0.53656 0.03116  -0.02740 0.05280  222 GLU A N   
1662 C CA  . GLU A 222 ? 0.72587 0.87557 0.61151 0.02188  -0.03038 0.03033  222 GLU A CA  
1663 C C   . GLU A 222 ? 0.60586 0.74807 0.52203 0.02253  -0.03356 0.02764  222 GLU A C   
1664 O O   . GLU A 222 ? 0.54232 0.66540 0.46645 0.02762  -0.03068 0.04006  222 GLU A O   
1665 C CB  . GLU A 222 ? 0.64181 0.78475 0.52938 0.00933  -0.01680 0.01840  222 GLU A CB  
1666 C CG  . GLU A 222 ? 0.88742 1.04208 0.74450 0.00657  -0.01231 0.01566  222 GLU A CG  
1667 C CD  . GLU A 222 ? 0.94636 1.10829 0.81049 -0.00526 -0.00485 -0.00656 222 GLU A CD  
1668 O OE1 . GLU A 222 ? 0.77042 0.94961 0.61180 -0.00805 -0.00477 -0.01551 222 GLU A OE1 
1669 O OE2 . GLU A 222 ? 0.83105 0.98083 0.72212 -0.01088 0.00084  -0.01508 222 GLU A OE2 
1670 N N   . GLY A 223 ? 0.47855 0.63524 0.41072 0.01654  -0.03837 0.01056  223 GLY A N   
1671 C CA  . GLY A 223 ? 0.54915 0.69776 0.50644 0.01484  -0.03876 0.00655  223 GLY A CA  
1672 C C   . GLY A 223 ? 0.47723 0.60371 0.44573 0.00700  -0.02846 0.00305  223 GLY A C   
1673 O O   . GLY A 223 ? 0.47504 0.59618 0.43767 0.00155  -0.02101 -0.00069 223 GLY A O   
1674 N N   . SER A 224 ? 0.50761 0.62303 0.49292 0.00723  -0.02862 0.00326  224 SER A N   
1675 C CA  . SER A 224 ? 0.39885 0.49468 0.39494 0.00251  -0.02229 0.00091  224 SER A CA  
1676 C C   . SER A 224 ? 0.61338 0.70647 0.62188 0.00020  -0.02476 -0.00530 224 SER A C   
1677 O O   . SER A 224 ? 0.47208 0.57292 0.48500 0.00427  -0.02911 -0.00339 224 SER A O   
1678 C CB  . SER A 224 ? 0.45704 0.53657 0.45517 0.00673  -0.01805 0.01255  224 SER A CB  
1679 O OG  . SER A 224 ? 0.72009 0.78590 0.72951 0.00251  -0.01362 0.00814  224 SER A OG  
1680 N N   . MET A 225 ? 0.51126 0.59301 0.52470 -0.00570 -0.02142 -0.01252 225 MET A N   
1681 C CA  . MET A 225 ? 0.40411 0.47740 0.42398 -0.00817 -0.02175 -0.01586 225 MET A CA  
1682 C C   . MET A 225 ? 0.54785 0.60188 0.56984 -0.00950 -0.01941 -0.01702 225 MET A C   
1683 O O   . MET A 225 ? 0.47856 0.52958 0.50101 -0.01030 -0.01707 -0.01974 225 MET A O   
1684 C CB  . MET A 225 ? 0.53497 0.61864 0.55611 -0.01501 -0.02135 -0.02586 225 MET A CB  
1685 C CG  . MET A 225 ? 0.46886 0.54745 0.48818 -0.02201 -0.01734 -0.03525 225 MET A CG  
1686 S SD  . MET A 225 ? 0.61641 0.70331 0.64047 -0.03328 -0.01402 -0.04944 225 MET A SD  
1687 C CE  . MET A 225 ? 0.51447 0.63180 0.53590 -0.03453 -0.01829 -0.05837 225 MET A CE  
1688 N N   . VAL A 226 ? 0.52521 0.56755 0.54827 -0.00895 -0.02038 -0.01564 226 VAL A N   
1689 C CA  . VAL A 226 ? 0.45759 0.48228 0.47947 -0.00905 -0.02062 -0.01695 226 VAL A CA  
1690 C C   . VAL A 226 ? 0.56964 0.58621 0.58525 -0.01475 -0.01768 -0.02061 226 VAL A C   
1691 O O   . VAL A 226 ? 0.49983 0.52101 0.51357 -0.01772 -0.01586 -0.02087 226 VAL A O   
1692 C CB  . VAL A 226 ? 0.45944 0.47573 0.48282 -0.00424 -0.02425 -0.01282 226 VAL A CB  
1693 C CG1 . VAL A 226 ? 0.48088 0.48054 0.49909 -0.00256 -0.02726 -0.01353 226 VAL A CG1 
1694 C CG2 . VAL A 226 ? 0.50438 0.52564 0.53712 -0.00097 -0.02457 -0.01075 226 VAL A CG2 
1695 N N   . LYS A 227 ? 0.53063 0.53474 0.54462 -0.01663 -0.01567 -0.02409 227 LYS A N   
1696 C CA  . LYS A 227 ? 0.54660 0.53510 0.55351 -0.02256 -0.01074 -0.02622 227 LYS A CA  
1697 C C   . LYS A 227 ? 0.66374 0.62743 0.66225 -0.01668 -0.01367 -0.02038 227 LYS A C   
1698 O O   . LYS A 227 ? 0.61942 0.57822 0.62350 -0.01002 -0.01778 -0.02062 227 LYS A O   
1699 C CB  . LYS A 227 ? 0.45764 0.44766 0.46900 -0.02922 -0.00537 -0.03551 227 LYS A CB  
1700 C CG  . LYS A 227 ? 0.68103 0.65280 0.68707 -0.03784 0.00258  -0.03854 227 LYS A CG  
1701 C CD  . LYS A 227 ? 0.65047 0.61109 0.66109 -0.04145 0.00755  -0.04706 227 LYS A CD  
1702 C CE  . LYS A 227 ? 0.69920 0.68304 0.71867 -0.05143 0.01144  -0.06078 227 LYS A CE  
1703 N NZ  . LYS A 227 ? 0.71393 0.68060 0.73629 -0.06200 0.02147  -0.07098 227 LYS A NZ  
1704 N N   . VAL A 228 ? 0.58191 0.53145 0.56677 -0.01849 -0.01170 -0.01549 228 VAL A N   
1705 C CA  . VAL A 228 ? 0.62434 0.54914 0.59484 -0.01181 -0.01577 -0.00823 228 VAL A CA  
1706 C C   . VAL A 228 ? 0.66527 0.56463 0.62346 -0.01802 -0.00682 -0.00639 228 VAL A C   
1707 O O   . VAL A 228 ? 0.59700 0.49538 0.54932 -0.02853 0.00293  -0.00770 228 VAL A O   
1708 C CB  . VAL A 228 ? 0.64452 0.56953 0.60287 -0.00851 -0.02010 -0.00317 228 VAL A CB  
1709 C CG1 . VAL A 228 ? 0.50201 0.40287 0.44118 -0.00021 -0.02664 0.00456  228 VAL A CG1 
1710 C CG2 . VAL A 228 ? 0.51283 0.46005 0.48606 -0.00395 -0.02678 -0.00609 228 VAL A CG2 
1711 N N   . THR A 229 ? 0.62681 0.62324 0.80081 -0.06614 0.05187  -0.02097 229 THR A N   
1712 C CA  . THR A 229 ? 0.59935 0.55733 0.72842 -0.07371 0.05269  -0.02213 229 THR A CA  
1713 C C   . THR A 229 ? 0.54028 0.48402 0.64881 -0.06726 0.05389  -0.02227 229 THR A C   
1714 O O   . THR A 229 ? 0.52238 0.48902 0.65324 -0.05567 0.05345  -0.02215 229 THR A O   
1715 C CB  . THR A 229 ? 0.62785 0.55736 0.72428 -0.06464 0.04764  -0.01815 229 THR A CB  
1716 O OG1 . THR A 229 ? 0.70055 0.62727 0.78718 -0.04184 0.04417  -0.01430 229 THR A OG1 
1717 C CG2 . THR A 229 ? 0.46938 0.41706 0.58803 -0.06715 0.04527  -0.01759 229 THR A CG2 
1718 N N   . PRO A 230 ? 0.65358 0.55841 0.71791 -0.07525 0.05511  -0.02281 230 PRO A N   
1719 C CA  . PRO A 230 ? 0.75110 0.63568 0.78707 -0.06446 0.05388  -0.02196 230 PRO A CA  
1720 C C   . PRO A 230 ? 0.74479 0.62410 0.76877 -0.03673 0.04639  -0.01879 230 PRO A C   
1721 O O   . PRO A 230 ? 0.70046 0.57965 0.71619 -0.02327 0.04395  -0.01974 230 PRO A O   
1722 C CB  . PRO A 230 ? 0.81066 0.64531 0.79349 -0.07983 0.05601  -0.02163 230 PRO A CB  
1723 C CG  . PRO A 230 ? 0.64509 0.47397 0.62810 -0.09668 0.05747  -0.02265 230 PRO A CG  
1724 C CD  . PRO A 230 ? 0.57475 0.45617 0.61632 -0.09835 0.05873  -0.02540 230 PRO A CD  
1725 N N   . ASP A 231 ? 0.61480 0.49424 0.63943 -0.02719 0.04261  -0.01630 231 ASP A N   
1726 C CA  . ASP A 231 ? 0.67831 0.55415 0.68871 -0.00085 0.03611  -0.01503 231 ASP A CA  
1727 C C   . ASP A 231 ? 0.82537 0.75010 0.88198 0.01014  0.03666  -0.01467 231 ASP A C   
1728 O O   . ASP A 231 ? 0.78160 0.71713 0.83616 0.03073  0.03298  -0.01601 231 ASP A O   
1729 C CB  . ASP A 231 ? 0.73897 0.57791 0.71093 0.00462  0.03143  -0.01339 231 ASP A CB  
1730 C CG  . ASP A 231 ? 0.95834 0.73930 0.87373 -0.00244 0.02938  -0.01336 231 ASP A CG  
1731 O OD1 . ASP A 231 ? 0.91656 0.68176 0.81162 0.00116  0.02863  -0.01391 231 ASP A OD1 
1732 O OD2 . ASP A 231 ? 1.15915 0.90863 1.04846 -0.01227 0.02833  -0.01284 231 ASP A OD2 
1733 N N   . ASP A 232 ? 0.64199 0.59616 0.73846 -0.00279 0.04085  -0.01336 232 ASP A N   
1734 C CA  . ASP A 232 ? 0.59901 0.59171 0.73216 0.00564  0.04165  -0.01141 232 ASP A CA  
1735 C C   . ASP A 232 ? 0.50516 0.52534 0.68087 -0.01022 0.04569  -0.01077 232 ASP A C   
1736 O O   . ASP A 232 ? 0.55934 0.57361 0.73865 -0.02605 0.04765  -0.01324 232 ASP A O   
1737 C CB  . ASP A 232 ? 0.61596 0.60290 0.73473 0.01707  0.03897  -0.00834 232 ASP A CB  
1738 C CG  . ASP A 232 ? 0.64860 0.61265 0.75223 0.00492  0.03810  -0.00678 232 ASP A CG  
1739 O OD1 . ASP A 232 ? 0.64636 0.62139 0.77337 -0.01210 0.04061  -0.00675 232 ASP A OD1 
1740 O OD2 . ASP A 232 ? 0.75418 0.69067 0.82284 0.01347  0.03415  -0.00677 232 ASP A OD2 
1741 N N   . VAL A 233 ? 0.52485 0.57533 0.73172 -0.00558 0.04690  -0.00809 233 VAL A N   
1742 C CA  . VAL A 233 ? 0.48969 0.56152 0.73288 -0.01663 0.04886  -0.00629 233 VAL A CA  
1743 C C   . VAL A 233 ? 0.51571 0.59296 0.76100 -0.01184 0.04812  0.00006  233 VAL A C   
1744 O O   . VAL A 233 ? 0.40137 0.48588 0.63979 0.00028  0.04868  0.00234  233 VAL A O   
1745 C CB  . VAL A 233 ? 0.56971 0.66793 0.84547 -0.01767 0.05110  -0.00846 233 VAL A CB  
1746 C CG1 . VAL A 233 ? 0.39845 0.51183 0.70744 -0.02753 0.05166  -0.00677 233 VAL A CG1 
1747 C CG2 . VAL A 233 ? 0.50979 0.60255 0.77934 -0.02048 0.05155  -0.01524 233 VAL A CG2 
1748 N N   . GLU A 234 ? 0.48956 0.56491 0.74295 -0.02054 0.04664  0.00200  234 GLU A N   
1749 C CA  . GLU A 234 ? 0.48174 0.55662 0.72970 -0.01628 0.04496  0.00796  234 GLU A CA  
1750 C C   . GLU A 234 ? 0.41964 0.51030 0.69676 -0.02201 0.04431  0.01201  234 GLU A C   
1751 O O   . GLU A 234 ? 0.38803 0.48006 0.67974 -0.03080 0.04192  0.00830  234 GLU A O   
1752 C CB  . GLU A 234 ? 0.49109 0.54182 0.71105 -0.01897 0.04122  0.00601  234 GLU A CB  
1753 C CG  . GLU A 234 ? 0.50882 0.53375 0.69450 -0.01569 0.04078  0.00171  234 GLU A CG  
1754 C CD  . GLU A 234 ? 0.64238 0.63955 0.79810 -0.02082 0.03715  -0.00050 234 GLU A CD  
1755 O OE1 . GLU A 234 ? 0.75638 0.75827 0.91858 -0.02476 0.03452  0.00084  234 GLU A OE1 
1756 O OE2 . GLU A 234 ? 0.77233 0.74069 0.89561 -0.02104 0.03631  -0.00379 234 GLU A OE2 
1757 N N   . LEU A 235 ? 0.33812 0.44006 0.62169 -0.01679 0.04630  0.01913  235 LEU A N   
1758 C CA  . LEU A 235 ? 0.33845 0.44668 0.63977 -0.02066 0.04472  0.02525  235 LEU A CA  
1759 C C   . LEU A 235 ? 0.48943 0.58815 0.77051 -0.01619 0.04163  0.03043  235 LEU A C   
1760 O O   . LEU A 235 ? 0.49383 0.59316 0.75718 -0.00862 0.04465  0.03401  235 LEU A O   
1761 C CB  . LEU A 235 ? 0.40083 0.52469 0.71946 -0.02124 0.04985  0.03047  235 LEU A CB  
1762 C CG  . LEU A 235 ? 0.38075 0.50506 0.71272 -0.02573 0.04893  0.03871  235 LEU A CG  
1763 C CD1 . LEU A 235 ? 0.39968 0.51816 0.74975 -0.03062 0.04248  0.03493  235 LEU A CD1 
1764 C CD2 . LEU A 235 ? 0.40817 0.54703 0.75276 -0.02938 0.05602  0.04268  235 LEU A CD2 
1765 N N   . ILE A 236 ? 0.43640 0.52881 0.72021 -0.01984 0.03519  0.02940  236 ILE A N   
1766 C CA  . ILE A 236 ? 0.47269 0.55470 0.73536 -0.01630 0.03028  0.03104  236 ILE A CA  
1767 C C   . ILE A 236 ? 0.57486 0.65854 0.84664 -0.01567 0.02486  0.03721  236 ILE A C   
1768 O O   . ILE A 236 ? 0.52555 0.61340 0.81813 -0.01948 0.02026  0.03395  236 ILE A O   
1769 C CB  . ILE A 236 ? 0.59641 0.66837 0.84896 -0.02174 0.02600  0.02118  236 ILE A CB  
1770 C CG1 . ILE A 236 ? 0.48126 0.54278 0.71602 -0.02139 0.03051  0.01654  236 ILE A CG1 
1771 C CG2 . ILE A 236 ? 0.42767 0.49075 0.66178 -0.01963 0.01933  0.02116  236 ILE A CG2 
1772 C CD1 . ILE A 236 ? 0.53781 0.58626 0.76167 -0.03119 0.02824  0.00735  236 ILE A CD1 
1773 N N   . HIS A 237 ? 0.40469 0.48423 0.65866 -0.00960 0.02484  0.04556  237 HIS A N   
1774 C CA  . HIS A 237 ? 0.51362 0.58902 0.76718 -0.00726 0.01839  0.05246  237 HIS A CA  
1775 C C   . HIS A 237 ? 0.57098 0.63850 0.80199 -0.00249 0.01123  0.05035  237 HIS A C   
1776 O O   . HIS A 237 ? 0.62557 0.68879 0.83445 0.00104  0.01430  0.04930  237 HIS A O   
1777 C CB  . HIS A 237 ? 0.43155 0.50747 0.68092 -0.00614 0.02472  0.06526  237 HIS A CB  
1778 C CG  . HIS A 237 ? 0.66761 0.74828 0.94080 -0.01257 0.02879  0.06759  237 HIS A CG  
1779 N ND1 . HIS A 237 ? 0.62018 0.71177 0.90919 -0.01677 0.03474  0.06096  237 HIS A ND1 
1780 C CD2 . HIS A 237 ? 0.53762 0.61061 0.81934 -0.01534 0.02675  0.07518  237 HIS A CD2 
1781 C CE1 . HIS A 237 ? 0.58443 0.67754 0.89277 -0.02252 0.03654  0.06363  237 HIS A CE1 
1782 N NE2 . HIS A 237 ? 0.62038 0.70051 0.92410 -0.02210 0.03184  0.07239  237 HIS A NE2 
1783 N N   . PHE A 238 ? 0.52688 0.59277 0.76298 -0.00112 0.00075  0.04867  238 PHE A N   
1784 C CA  . PHE A 238 ? 0.61889 0.68081 0.83834 0.00195  -0.00814 0.04322  238 PHE A CA  
1785 C C   . PHE A 238 ? 0.57529 0.63521 0.79547 0.00861  -0.01909 0.04769  238 PHE A C   
1786 O O   . PHE A 238 ? 0.56190 0.62254 0.79966 0.00952  -0.02142 0.05113  238 PHE A O   
1787 C CB  . PHE A 238 ? 0.54926 0.61668 0.77818 -0.00617 -0.01139 0.02814  238 PHE A CB  
1788 C CG  . PHE A 238 ? 0.59029 0.67098 0.85086 -0.01115 -0.01436 0.02105  238 PHE A CG  
1789 C CD1 . PHE A 238 ? 0.47904 0.56406 0.75695 -0.01607 -0.00621 0.02087  238 PHE A CD1 
1790 C CD2 . PHE A 238 ? 0.46221 0.55331 0.73527 -0.00953 -0.02588 0.01317  238 PHE A CD2 
1791 C CE1 . PHE A 238 ? 0.42024 0.51795 0.72611 -0.01955 -0.00879 0.01336  238 PHE A CE1 
1792 C CE2 . PHE A 238 ? 0.47682 0.58310 0.77942 -0.01194 -0.02880 0.00491  238 PHE A CE2 
1793 C CZ  . PHE A 238 ? 0.46487 0.57366 0.78337 -0.01718 -0.01988 0.00507  238 PHE A CZ  
1794 N N   . PRO A 239 ? 0.69832 0.75345 0.89718 0.01450  -0.02694 0.04726  239 PRO A N   
1795 C CA  . PRO A 239 ? 0.70026 0.75264 0.89698 0.02312  -0.03986 0.05030  239 PRO A CA  
1796 C C   . PRO A 239 ? 0.58964 0.65664 0.81157 0.02247  -0.05139 0.03591  239 PRO A C   
1797 O O   . PRO A 239 ? 0.45545 0.53510 0.69095 0.01337  -0.04987 0.02248  239 PRO A O   
1798 C CB  . PRO A 239 ? 0.64515 0.69040 0.80994 0.02935  -0.04432 0.05205  239 PRO A CB  
1799 C CG  . PRO A 239 ? 0.69520 0.74238 0.85300 0.02245  -0.03811 0.04276  239 PRO A CG  
1800 C CD  . PRO A 239 ? 0.54851 0.59772 0.72040 0.01558  -0.02483 0.04488  239 PRO A CD  
1801 N N   . PHE A 240 ? 0.62517 0.69012 0.85200 0.03250  -0.06310 0.03852  240 PHE A N   
1802 C CA  . PHE A 240 ? 0.57263 0.65646 0.82545 0.03504  -0.07526 0.02319  240 PHE A CA  
1803 C C   . PHE A 240 ? 0.56790 0.66711 0.81652 0.03354  -0.08403 0.00895  240 PHE A C   
1804 O O   . PHE A 240 ? 0.67011 0.78977 0.93827 0.02292  -0.08308 -0.00694 240 PHE A O   
1805 C CB  . PHE A 240 ? 0.64243 0.71739 0.89664 0.05019  -0.08849 0.02852  240 PHE A CB  
1806 C CG  . PHE A 240 ? 0.63333 0.69281 0.89558 0.05004  -0.08204 0.03925  240 PHE A CG  
1807 C CD1 . PHE A 240 ? 0.65905 0.72635 0.94205 0.03790  -0.06893 0.03610  240 PHE A CD1 
1808 C CD2 . PHE A 240 ? 0.64369 0.67847 0.89074 0.06185  -0.09008 0.05198  240 PHE A CD2 
1809 C CE1 . PHE A 240 ? 0.57455 0.62819 0.86554 0.03687  -0.06367 0.04457  240 PHE A CE1 
1810 C CE2 . PHE A 240 ? 0.70536 0.72213 0.95790 0.05962  -0.08436 0.06149  240 PHE A CE2 
1811 C CZ  . PHE A 240 ? 0.59278 0.62068 0.86892 0.04682  -0.07113 0.05713  240 PHE A CZ  
1812 N N   . LEU A 241 ? 0.69695 0.78661 0.91907 0.04297  -0.09261 0.01399  241 LEU A N   
1813 C CA  . LEU A 241 ? 0.84151 0.94567 1.05864 0.04294  -0.10369 -0.00014 241 LEU A CA  
1814 C C   . LEU A 241 ? 0.75462 0.84706 0.94425 0.03524  -0.09559 0.00167  241 LEU A C   
1815 O O   . LEU A 241 ? 0.75640 0.83009 0.92722 0.03490  -0.08362 0.01539  241 LEU A O   
1816 C CB  . LEU A 241 ? 0.71582 0.81811 0.92082 0.06121  -0.12198 0.00174  241 LEU A CB  
1817 C CG  . LEU A 241 ? 0.95871 1.08015 1.19158 0.07195  -0.13694 -0.00913 241 LEU A CG  
1818 C CD1 . LEU A 241 ? 0.65263 0.81090 0.92143 0.05971  -0.13743 -0.03239 241 LEU A CD1 
1819 C CD2 . LEU A 241 ? 0.63979 0.74297 0.87882 0.07860  -0.13327 0.00416  241 LEU A CD2 
1820 N N   . GLU A 242 ? 1.05572 1.16058 1.24334 0.02912  -0.10268 -0.01382 242 GLU A N   
1821 C CA  . GLU A 242 ? 0.97591 1.06699 1.13532 0.02254  -0.09768 -0.01511 242 GLU A CA  
1822 C C   . GLU A 242 ? 1.00077 1.07407 1.12573 0.03718  -0.10151 -0.00214 242 GLU A C   
1823 O O   . GLU A 242 ? 0.97541 1.05406 1.09167 0.04735  -0.11633 -0.00542 242 GLU A O   
1824 C CB  . GLU A 242 ? 0.96170 1.06930 1.12696 0.01100  -0.10592 -0.03575 242 GLU A CB  
1825 N N   . GLU A 243 ? 1.24032 1.29474 1.34529 0.03869  -0.08826 0.01184  243 GLU A N   
1826 C CA  . GLU A 243 ? 1.37460 1.41388 1.44544 0.05092  -0.08857 0.02474  243 GLU A CA  
1827 C C   . GLU A 243 ? 1.43477 1.46702 1.47798 0.04992  -0.09075 0.01606  243 GLU A C   
1828 O O   . GLU A 243 ? 1.40843 1.43048 1.43988 0.04480  -0.07972 0.01535  243 GLU A O   
1829 C CB  . GLU A 243 ? 1.32614 1.35447 1.39040 0.05203  -0.07262 0.04167  243 GLU A CB  
1830 C CG  . GLU A 243 ? 1.17632 1.20704 1.26467 0.05196  -0.07049 0.05045  243 GLU A CG  
1831 C CD  . GLU A 243 ? 1.26833 1.28526 1.33712 0.05819  -0.06377 0.06985  243 GLU A CD  
1832 O OE1 . GLU A 243 ? 1.38452 1.39810 1.44000 0.05543  -0.04949 0.07694  243 GLU A OE1 
1833 O OE2 . GLU A 243 ? 1.42573 1.43500 1.49111 0.06583  -0.07296 0.07750  243 GLU A OE2 
1834 N N   . ASN A 244 ? 1.46300 1.49964 1.49436 0.05618  -0.10617 0.00859  244 ASN A N   
1835 C CA  . ASN A 244 ? 1.40908 1.43806 1.41310 0.05527  -0.11042 -0.00137 244 ASN A CA  
1836 C C   . ASN A 244 ? 1.43503 1.44612 1.40227 0.06538  -0.10186 0.01115  244 ASN A C   
1837 O O   . ASN A 244 ? 1.36181 1.36951 1.31731 0.07603  -0.09990 0.02662  244 ASN A O   
1838 C CB  . ASN A 244 ? 1.35572 1.39707 1.35700 0.06056  -0.13015 -0.01288 244 ASN A CB  
1839 C CG  . ASN A 244 ? 1.42007 1.48648 1.45969 0.05146  -0.13892 -0.02773 244 ASN A CG  
1840 O OD1 . ASN A 244 ? 1.44837 1.52027 1.50775 0.03482  -0.13166 -0.03739 244 ASN A OD1 
1841 N ND2 . ASN A 244 ? 1.49844 1.58072 1.54747 0.06302  -0.15477 -0.03015 244 ASN A ND2 
1842 N N   . LEU A 245 ? 1.47114 1.46989 1.41826 0.06182  -0.09666 0.00389  245 LEU A N   
1843 C CA  . LEU A 245 ? 1.29482 1.28063 1.20734 0.07260  -0.08856 0.01233  245 LEU A CA  
1844 C C   . LEU A 245 ? 1.08294 1.06562 0.96478 0.08317  -0.10123 0.00918  245 LEU A C   
1845 O O   . LEU A 245 ? 0.96430 0.94903 0.84518 0.07928  -0.11515 -0.00586 245 LEU A O   
1846 C CB  . LEU A 245 ? 1.11415 1.08560 1.01490 0.06811  -0.07926 0.00475  245 LEU A CB  
1847 C CG  . LEU A 245 ? 0.92721 0.88694 0.79060 0.08080  -0.07248 0.00753  245 LEU A CG  
1848 N N   . TYR A 246 ? 0.99408 0.97358 0.85107 0.09553  -0.09626 0.02325  246 TYR A N   
1849 C CA  . TYR A 246 ? 0.86799 0.84203 0.68811 0.10726  -0.10526 0.02179  246 TYR A CA  
1850 C C   . TYR A 246 ? 0.96015 0.92876 0.75105 0.11612  -0.09011 0.03293  246 TYR A C   
1851 O O   . TYR A 246 ? 1.13338 1.10638 0.93579 0.11371  -0.07465 0.04475  246 TYR A O   
1852 C CB  . TYR A 246 ? 0.83414 0.81388 0.65297 0.11474  -0.11972 0.02791  246 TYR A CB  
1853 C CG  . TYR A 246 ? 1.12570 1.10310 0.94136 0.12002  -0.11134 0.04992  246 TYR A CG  
1854 C CD1 . TYR A 246 ? 1.16224 1.14423 1.01144 0.11356  -0.10806 0.05716  246 TYR A CD1 
1855 C CD2 . TYR A 246 ? 1.09941 1.06851 0.87633 0.13036  -0.10664 0.06313  246 TYR A CD2 
1856 C CE1 . TYR A 246 ? 1.15746 1.13241 1.00113 0.11639  -0.10072 0.07708  246 TYR A CE1 
1857 C CE2 . TYR A 246 ? 1.17829 1.14174 0.94892 0.13180  -0.09809 0.08383  246 TYR A CE2 
1858 C CZ  . TYR A 246 ? 1.21969 1.18436 1.02347 0.12442  -0.09554 0.09075  246 TYR A CZ  
1859 O OH  . TYR A 246 ? 1.24595 1.20029 1.04100 0.12400  -0.08739 0.11107  246 TYR A OH  
1860 N N   . PHE A 247 ? 0.84767 0.80944 0.60158 0.12604  -0.09438 0.02757  247 PHE A N   
1861 C CA  . PHE A 247 ? 0.93326 0.89362 0.65863 0.13506  -0.07992 0.03340  247 PHE A CA  
1862 C C   . PHE A 247 ? 0.93346 0.89631 0.62954 0.14495  -0.07899 0.04804  247 PHE A C   
1863 O O   . PHE A 247 ? 0.96888 0.92753 0.64890 0.15046  -0.09456 0.04651  247 PHE A O   
1864 C CB  . PHE A 247 ? 0.86169 0.81018 0.56182 0.14035  -0.08345 0.01568  247 PHE A CB  
1865 C CG  . PHE A 247 ? 0.84143 0.78009 0.56179 0.12995  -0.08392 0.00208  247 PHE A CG  
1866 C CD1 . PHE A 247 ? 0.81385 0.75583 0.55567 0.12536  -0.06968 0.00689  247 PHE A CD1 
1867 C CD2 . PHE A 247 ? 0.85379 0.77889 0.56930 0.12380  -0.09859 -0.01575 247 PHE A CD2 
1868 C CE1 . PHE A 247 ? 0.80070 0.72968 0.55590 0.11613  -0.07027 -0.00454 247 PHE A CE1 
1869 C CE2 . PHE A 247 ? 0.84168 0.75318 0.57073 0.11192  -0.09808 -0.02714 247 PHE A CE2 
1870 C CZ  . PHE A 247 ? 0.81604 0.72794 0.56335 0.10881  -0.08392 -0.02085 247 PHE A CZ  
1871 N N   . GLN A 248 ? 1.16084 1.13126 0.84934 0.14648  -0.06061 0.06197  248 GLN A N   
1872 C CA  . GLN A 248 ? 1.09899 1.07074 0.75221 0.15420  -0.05517 0.07586  248 GLN A CA  
1873 C C   . GLN A 248 ? 1.02244 0.99962 0.64416 0.16440  -0.04563 0.06820  248 GLN A C   
1874 O O   . GLN A 248 ? 1.16439 1.14929 0.79731 0.16424  -0.03443 0.06076  248 GLN A O   
1875 C CB  . GLN A 248 ? 1.15499 1.13303 0.81961 0.14607  -0.03979 0.09665  248 GLN A CB  
1876 N N   . SER A 249 ? 1.01675 0.98995 0.59756 0.17496  -0.05085 0.06926  249 SER A N   
1877 C CA  . SER A 249 ? 1.21659 1.19495 0.76381 0.18711  -0.04399 0.05949  249 SER A CA  
1878 C C   . SER A 249 ? 1.41402 1.41221 0.94959 0.18725  -0.02022 0.07314  249 SER A C   
1879 O O   . SER A 249 ? 1.35993 1.36202 0.85964 0.19244  -0.01476 0.08242  249 SER A O   
1880 C CB  . SER A 249 ? 1.07804 1.04498 0.58614 0.19825  -0.06037 0.05274  249 SER A CB  
1881 N N   . HIS A 250 ? 1.33553 1.34821 0.90187 0.18059  -0.00557 0.07353  250 HIS A N   
1882 C CA  . HIS A 250 ? 1.31420 1.35288 0.87517 0.17979  0.01786  0.08174  250 HIS A CA  
1883 C C   . HIS A 250 ? 1.25356 1.30419 0.78145 0.19668  0.02331  0.06752  250 HIS A C   
1884 O O   . HIS A 250 ? 1.29776 1.33350 0.81288 0.20832  0.00960  0.04970  250 HIS A O   
1885 C CB  . HIS A 250 ? 1.25153 1.30513 0.85517 0.17049  0.02960  0.08176  250 HIS A CB  
1886 C CG  . HIS A 250 ? 1.23010 1.28027 0.86173 0.15320  0.03207  0.09930  250 HIS A CG  
1887 N ND1 . HIS A 250 ? 1.17566 1.22183 0.84868 0.14440  0.02837  0.09679  250 HIS A ND1 
1888 C CD2 . HIS A 250 ? 1.30091 1.34817 0.92225 0.14336  0.03772  0.11939  250 HIS A CD2 
1889 C CE1 . HIS A 250 ? 1.14686 1.18936 0.83571 0.13089  0.03120  0.11346  250 HIS A CE1 
1890 N NE2 . HIS A 250 ? 1.42623 1.46705 1.08343 0.12987  0.03654  0.12771  250 HIS A NE2 
1891 N N   . HIS A 251 ? 1.31207 1.39033 0.82555 0.19737  0.04390  0.07456  251 HIS A N   
1892 C CA  . HIS A 251 ? 1.52617 1.62066 1.00523 0.21451  0.05072  0.06181  251 HIS A CA  
1893 C C   . HIS A 251 ? 1.46670 1.59967 0.96153 0.21710  0.07229  0.05633  251 HIS A C   
1894 O O   . HIS A 251 ? 1.40457 1.55946 0.92127 0.20190  0.08877  0.07009  251 HIS A O   
1895 C CB  . HIS A 251 ? 1.49980 1.59496 0.93449 0.21565  0.05421  0.07373  251 HIS A CB  
1896 C CG  . HIS A 251 ? 1.58954 1.65260 0.99714 0.22325  0.03077  0.06977  251 HIS A CG  
1897 N ND1 . HIS A 251 ? 1.50656 1.54665 0.91322 0.21376  0.01813  0.08488  251 HIS A ND1 
1898 C CD2 . HIS A 251 ? 1.52698 1.57791 0.90734 0.23999  0.01677  0.05108  251 HIS A CD2 
1899 C CE1 . HIS A 251 ? 1.46390 1.48316 0.84596 0.22434  -0.00266 0.07519  251 HIS A CE1 
1900 N NE2 . HIS A 251 ? 1.45490 1.47948 0.82051 0.23905  -0.00358 0.05485  251 HIS A NE2 
1901 N N   . HIS A 252 ? 1.45378 1.59475 0.93667 0.23700  0.07127  0.03500  252 HIS A N   
1902 C CA  . HIS A 252 ? 1.52466 1.70526 1.02077 0.24508  0.08912  0.02520  252 HIS A CA  
1903 C C   . HIS A 252 ? 1.53137 1.75326 1.01039 0.24058  0.11233  0.03476  252 HIS A C   
1904 O O   . HIS A 252 ? 1.52233 1.74889 0.96100 0.25136  0.11415  0.03107  252 HIS A O   
1905 C CB  . HIS A 252 ? 1.48023 1.65483 0.95892 0.27136  0.08030  -0.00086 252 HIS A CB  
1906 C CG  . HIS A 252 ? 1.57756 1.72567 1.08143 0.27454  0.06653  -0.01200 252 HIS A CG  
1907 N ND1 . HIS A 252 ? 1.61488 1.72481 1.09861 0.28879  0.04731  -0.02935 252 HIS A ND1 
1908 C CD2 . HIS A 252 ? 1.53252 1.68470 1.07726 0.26411  0.06938  -0.00804 252 HIS A CD2 
1909 C CE1 . HIS A 252 ? 1.56624 1.65659 1.07567 0.28622  0.03965  -0.03467 252 HIS A CE1 
1910 N NE2 . HIS A 252 ? 1.54721 1.66357 1.09406 0.27227  0.05255  -0.02209 252 HIS A NE2 
# 
