data_9CAH
# 
_entry.id   9CAH 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CAH         pdb_00009cah 10.2210/pdb9cah/pdb 
WWPDB D_1000285098 ?            ?                   
EMDB  EMD-45391    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-05 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CAH 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-17 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Human TOP3B-TDRD3 complex' 
_pdbx_database_related.db_id          EMD-45391 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 Yves.Pommier@nih.gov Yves Pommier ? 'principal investigator/group leader' 0000-0002-3108-0758 
3 weiy@niddk.nih.gov   Wei  Yang    ? 'principal investigator/group leader' 0000-0002-3591-2195 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yang, X.'    1 ? 
'Chen, X.'    2 ? 
'Yang, W.'    3 ? 
'Pommier, Y.' 4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                834 
_citation.page_last                 834 
_citation.title                     
'Structural insights into human topoisomerase 3 beta DNA and RNA catalysis and nucleic acid gate dynamics.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-55959-y 
_citation.pdbx_database_id_PubMed   39828754 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yang, X.'    1 0000-0003-0689-1417 
primary 'Chen, X.'    2 0000-0002-1818-9206 
primary 'Yang, W.'    3 0000-0002-3591-2195 
primary 'Pommier, Y.' 4 0000-0002-3108-0758 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'DNA topoisomerase 3-beta-1'        81149.922 1 5.6.2.1 ? ? ? 
2 polymer     man 'Tudor domain-containing protein 3' 20465.318 1 ?       ? ? ? 
3 non-polymer syn 'MANGANESE (II) ION'                54.938    1 ?       ? ? ? 
4 non-polymer syn 'ZINC ION'                          65.409    3 ?       ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'DNA topoisomerase III beta-1' 
2 TDRD3                          
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;HMKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTLDFLGKYNKWDKVDPA
ELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTD
ICNAMACLGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPET
YWVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQ
HAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEA
ELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVG
EVKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYYKIDAELVLPT
IRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPS
RLHCSHCDETYTLPNNGTIKLYKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHS
;
;HMKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTLDFLGKYNKWDKVDPA
ELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTD
ICNAMACLGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPET
YWVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQ
HAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEA
ELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVG
EVKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYYKIDAELVLPT
IRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPS
RLHCSHCDETYTLPNNGTIKLYKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHS
;
A ? 
2 'polypeptide(L)' no no 
;MAQVAGAALSQAGWYLSDEGIEACTSSPDKVNVNDIILIALNTDLRTIGKKFLPSDINSGKVEKLEGPCVLQIQKIRNVA
APKDNEESQAAPRMLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGEVEHLIEK
WELQRSLSKHNRSNIGTEGGPPPFVPFGQ
;
;MAQVAGAALSQAGWYLSDEGIEACTSSPDKVNVNDIILIALNTDLRTIGKKFLPSDINSGKVEKLEGPCVLQIQKIRNVA
APKDNEESQAAPRMLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGEVEHLIEK
WELQRSLSKHNRSNIGTEGGPPPFVPFGQ
;
B ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 'MANGANESE (II) ION' MN 
4 'ZINC ION'           ZN 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   HIS n 
1 2   MET n 
1 3   LYS n 
1 4   THR n 
1 5   VAL n 
1 6   LEU n 
1 7   MET n 
1 8   VAL n 
1 9   ALA n 
1 10  GLU n 
1 11  LYS n 
1 12  PRO n 
1 13  SER n 
1 14  LEU n 
1 15  ALA n 
1 16  GLN n 
1 17  SER n 
1 18  ILE n 
1 19  ALA n 
1 20  LYS n 
1 21  ILE n 
1 22  LEU n 
1 23  SER n 
1 24  ARG n 
1 25  GLY n 
1 26  SER n 
1 27  LEU n 
1 28  SER n 
1 29  SER n 
1 30  HIS n 
1 31  LYS n 
1 32  GLY n 
1 33  LEU n 
1 34  ASN n 
1 35  GLY n 
1 36  ALA n 
1 37  CYS n 
1 38  SER n 
1 39  VAL n 
1 40  HIS n 
1 41  GLU n 
1 42  TYR n 
1 43  THR n 
1 44  GLY n 
1 45  THR n 
1 46  PHE n 
1 47  ALA n 
1 48  GLY n 
1 49  GLN n 
1 50  PRO n 
1 51  VAL n 
1 52  ARG n 
1 53  PHE n 
1 54  LYS n 
1 55  MET n 
1 56  THR n 
1 57  SER n 
1 58  VAL n 
1 59  CYS n 
1 60  GLY n 
1 61  HIS n 
1 62  VAL n 
1 63  MET n 
1 64  THR n 
1 65  LEU n 
1 66  ASP n 
1 67  PHE n 
1 68  LEU n 
1 69  GLY n 
1 70  LYS n 
1 71  TYR n 
1 72  ASN n 
1 73  LYS n 
1 74  TRP n 
1 75  ASP n 
1 76  LYS n 
1 77  VAL n 
1 78  ASP n 
1 79  PRO n 
1 80  ALA n 
1 81  GLU n 
1 82  LEU n 
1 83  PHE n 
1 84  SER n 
1 85  GLN n 
1 86  ALA n 
1 87  PRO n 
1 88  THR n 
1 89  GLU n 
1 90  LYS n 
1 91  LYS n 
1 92  GLU n 
1 93  ALA n 
1 94  ASN n 
1 95  PRO n 
1 96  LYS n 
1 97  LEU n 
1 98  ASN n 
1 99  MET n 
1 100 VAL n 
1 101 LYS n 
1 102 PHE n 
1 103 LEU n 
1 104 GLN n 
1 105 VAL n 
1 106 GLU n 
1 107 GLY n 
1 108 ARG n 
1 109 GLY n 
1 110 CYS n 
1 111 ASP n 
1 112 TYR n 
1 113 ILE n 
1 114 VAL n 
1 115 LEU n 
1 116 TRP n 
1 117 LEU n 
1 118 ASP n 
1 119 CYS n 
1 120 ASP n 
1 121 LYS n 
1 122 GLU n 
1 123 GLY n 
1 124 GLU n 
1 125 ASN n 
1 126 ILE n 
1 127 CYS n 
1 128 PHE n 
1 129 GLU n 
1 130 VAL n 
1 131 LEU n 
1 132 ASP n 
1 133 ALA n 
1 134 VAL n 
1 135 LEU n 
1 136 PRO n 
1 137 VAL n 
1 138 MET n 
1 139 ASN n 
1 140 LYS n 
1 141 ALA n 
1 142 HIS n 
1 143 GLY n 
1 144 GLY n 
1 145 GLU n 
1 146 LYS n 
1 147 THR n 
1 148 VAL n 
1 149 PHE n 
1 150 ARG n 
1 151 ALA n 
1 152 ARG n 
1 153 PHE n 
1 154 SER n 
1 155 SER n 
1 156 ILE n 
1 157 THR n 
1 158 ASP n 
1 159 THR n 
1 160 ASP n 
1 161 ILE n 
1 162 CYS n 
1 163 ASN n 
1 164 ALA n 
1 165 MET n 
1 166 ALA n 
1 167 CYS n 
1 168 LEU n 
1 169 GLY n 
1 170 GLU n 
1 171 PRO n 
1 172 ASP n 
1 173 HIS n 
1 174 ASN n 
1 175 GLU n 
1 176 ALA n 
1 177 LEU n 
1 178 SER n 
1 179 VAL n 
1 180 ASP n 
1 181 ALA n 
1 182 ARG n 
1 183 GLN n 
1 184 GLU n 
1 185 LEU n 
1 186 ASP n 
1 187 LEU n 
1 188 ARG n 
1 189 ILE n 
1 190 GLY n 
1 191 CYS n 
1 192 ALA n 
1 193 PHE n 
1 194 THR n 
1 195 ARG n 
1 196 PHE n 
1 197 GLN n 
1 198 THR n 
1 199 LYS n 
1 200 TYR n 
1 201 PHE n 
1 202 GLN n 
1 203 GLY n 
1 204 LYS n 
1 205 TYR n 
1 206 GLY n 
1 207 ASP n 
1 208 LEU n 
1 209 ASP n 
1 210 SER n 
1 211 SER n 
1 212 LEU n 
1 213 ILE n 
1 214 SER n 
1 215 PHE n 
1 216 GLY n 
1 217 PRO n 
1 218 CYS n 
1 219 GLN n 
1 220 THR n 
1 221 PRO n 
1 222 THR n 
1 223 LEU n 
1 224 GLY n 
1 225 PHE n 
1 226 CYS n 
1 227 VAL n 
1 228 GLU n 
1 229 ARG n 
1 230 HIS n 
1 231 ASP n 
1 232 LYS n 
1 233 ILE n 
1 234 GLN n 
1 235 SER n 
1 236 PHE n 
1 237 LYS n 
1 238 PRO n 
1 239 GLU n 
1 240 THR n 
1 241 TYR n 
1 242 TRP n 
1 243 VAL n 
1 244 LEU n 
1 245 GLN n 
1 246 ALA n 
1 247 LYS n 
1 248 VAL n 
1 249 ASN n 
1 250 THR n 
1 251 ASP n 
1 252 LYS n 
1 253 ASP n 
1 254 ARG n 
1 255 SER n 
1 256 LEU n 
1 257 LEU n 
1 258 LEU n 
1 259 ASP n 
1 260 TRP n 
1 261 ASP n 
1 262 ARG n 
1 263 VAL n 
1 264 ARG n 
1 265 VAL n 
1 266 PHE n 
1 267 ASP n 
1 268 ARG n 
1 269 GLU n 
1 270 ILE n 
1 271 ALA n 
1 272 GLN n 
1 273 MET n 
1 274 PHE n 
1 275 LEU n 
1 276 ASN n 
1 277 MET n 
1 278 THR n 
1 279 LYS n 
1 280 LEU n 
1 281 GLU n 
1 282 LYS n 
1 283 GLU n 
1 284 ALA n 
1 285 GLN n 
1 286 VAL n 
1 287 GLU n 
1 288 ALA n 
1 289 THR n 
1 290 SER n 
1 291 ARG n 
1 292 LYS n 
1 293 GLU n 
1 294 LYS n 
1 295 ALA n 
1 296 LYS n 
1 297 GLN n 
1 298 ARG n 
1 299 PRO n 
1 300 LEU n 
1 301 ALA n 
1 302 LEU n 
1 303 ASN n 
1 304 THR n 
1 305 VAL n 
1 306 GLU n 
1 307 MET n 
1 308 LEU n 
1 309 ARG n 
1 310 VAL n 
1 311 ALA n 
1 312 SER n 
1 313 SER n 
1 314 SER n 
1 315 LEU n 
1 316 GLY n 
1 317 MET n 
1 318 GLY n 
1 319 PRO n 
1 320 GLN n 
1 321 HIS n 
1 322 ALA n 
1 323 MET n 
1 324 GLN n 
1 325 THR n 
1 326 ALA n 
1 327 GLU n 
1 328 ARG n 
1 329 LEU n 
1 330 TYR n 
1 331 THR n 
1 332 GLN n 
1 333 GLY n 
1 334 TYR n 
1 335 ILE n 
1 336 SER n 
1 337 TYR n 
1 338 PRO n 
1 339 ARG n 
1 340 THR n 
1 341 GLU n 
1 342 THR n 
1 343 THR n 
1 344 HIS n 
1 345 TYR n 
1 346 PRO n 
1 347 GLU n 
1 348 ASN n 
1 349 PHE n 
1 350 ASP n 
1 351 LEU n 
1 352 LYS n 
1 353 GLY n 
1 354 SER n 
1 355 LEU n 
1 356 ARG n 
1 357 GLN n 
1 358 GLN n 
1 359 ALA n 
1 360 ASN n 
1 361 HIS n 
1 362 PRO n 
1 363 TYR n 
1 364 TRP n 
1 365 ALA n 
1 366 ASP n 
1 367 THR n 
1 368 VAL n 
1 369 LYS n 
1 370 ARG n 
1 371 LEU n 
1 372 LEU n 
1 373 ALA n 
1 374 GLU n 
1 375 GLY n 
1 376 ILE n 
1 377 ASN n 
1 378 ARG n 
1 379 PRO n 
1 380 ARG n 
1 381 LYS n 
1 382 GLY n 
1 383 HIS n 
1 384 ASP n 
1 385 ALA n 
1 386 GLY n 
1 387 ASP n 
1 388 HIS n 
1 389 PRO n 
1 390 PRO n 
1 391 ILE n 
1 392 THR n 
1 393 PRO n 
1 394 MET n 
1 395 LYS n 
1 396 SER n 
1 397 ALA n 
1 398 THR n 
1 399 GLU n 
1 400 ALA n 
1 401 GLU n 
1 402 LEU n 
1 403 GLY n 
1 404 GLY n 
1 405 ASP n 
1 406 ALA n 
1 407 TRP n 
1 408 ARG n 
1 409 LEU n 
1 410 TYR n 
1 411 GLU n 
1 412 TYR n 
1 413 ILE n 
1 414 THR n 
1 415 ARG n 
1 416 HIS n 
1 417 PHE n 
1 418 ILE n 
1 419 ALA n 
1 420 THR n 
1 421 VAL n 
1 422 SER n 
1 423 HIS n 
1 424 ASP n 
1 425 CYS n 
1 426 LYS n 
1 427 TYR n 
1 428 LEU n 
1 429 GLN n 
1 430 SER n 
1 431 THR n 
1 432 ILE n 
1 433 SER n 
1 434 PHE n 
1 435 ARG n 
1 436 ILE n 
1 437 GLY n 
1 438 PRO n 
1 439 GLU n 
1 440 LEU n 
1 441 PHE n 
1 442 THR n 
1 443 CYS n 
1 444 SER n 
1 445 GLY n 
1 446 LYS n 
1 447 THR n 
1 448 VAL n 
1 449 LEU n 
1 450 SER n 
1 451 PRO n 
1 452 GLY n 
1 453 PHE n 
1 454 THR n 
1 455 GLU n 
1 456 VAL n 
1 457 MET n 
1 458 PRO n 
1 459 TRP n 
1 460 GLN n 
1 461 SER n 
1 462 VAL n 
1 463 PRO n 
1 464 LEU n 
1 465 GLU n 
1 466 GLU n 
1 467 SER n 
1 468 LEU n 
1 469 PRO n 
1 470 THR n 
1 471 CYS n 
1 472 GLN n 
1 473 ARG n 
1 474 GLY n 
1 475 ASP n 
1 476 ALA n 
1 477 PHE n 
1 478 PRO n 
1 479 VAL n 
1 480 GLY n 
1 481 GLU n 
1 482 VAL n 
1 483 LYS n 
1 484 MET n 
1 485 LEU n 
1 486 GLU n 
1 487 LYS n 
1 488 GLN n 
1 489 THR n 
1 490 ASN n 
1 491 PRO n 
1 492 PRO n 
1 493 ASP n 
1 494 TYR n 
1 495 LEU n 
1 496 THR n 
1 497 GLU n 
1 498 ALA n 
1 499 GLU n 
1 500 LEU n 
1 501 ILE n 
1 502 THR n 
1 503 LEU n 
1 504 MET n 
1 505 GLU n 
1 506 LYS n 
1 507 HIS n 
1 508 GLY n 
1 509 ILE n 
1 510 GLY n 
1 511 THR n 
1 512 ASP n 
1 513 ALA n 
1 514 SER n 
1 515 ILE n 
1 516 PRO n 
1 517 VAL n 
1 518 HIS n 
1 519 ILE n 
1 520 ASN n 
1 521 ASN n 
1 522 ILE n 
1 523 CYS n 
1 524 GLN n 
1 525 ARG n 
1 526 ASN n 
1 527 TYR n 
1 528 VAL n 
1 529 THR n 
1 530 VAL n 
1 531 GLU n 
1 532 SER n 
1 533 GLY n 
1 534 ARG n 
1 535 ARG n 
1 536 LEU n 
1 537 LYS n 
1 538 PRO n 
1 539 THR n 
1 540 ASN n 
1 541 LEU n 
1 542 GLY n 
1 543 ILE n 
1 544 VAL n 
1 545 LEU n 
1 546 VAL n 
1 547 HIS n 
1 548 GLY n 
1 549 TYR n 
1 550 TYR n 
1 551 LYS n 
1 552 ILE n 
1 553 ASP n 
1 554 ALA n 
1 555 GLU n 
1 556 LEU n 
1 557 VAL n 
1 558 LEU n 
1 559 PRO n 
1 560 THR n 
1 561 ILE n 
1 562 ARG n 
1 563 SER n 
1 564 ALA n 
1 565 VAL n 
1 566 GLU n 
1 567 LYS n 
1 568 GLN n 
1 569 LEU n 
1 570 ASN n 
1 571 LEU n 
1 572 ILE n 
1 573 ALA n 
1 574 GLN n 
1 575 GLY n 
1 576 LYS n 
1 577 ALA n 
1 578 ASP n 
1 579 TYR n 
1 580 ARG n 
1 581 GLN n 
1 582 VAL n 
1 583 LEU n 
1 584 GLY n 
1 585 HIS n 
1 586 THR n 
1 587 LEU n 
1 588 ASP n 
1 589 VAL n 
1 590 PHE n 
1 591 LYS n 
1 592 ARG n 
1 593 LYS n 
1 594 PHE n 
1 595 HIS n 
1 596 TYR n 
1 597 PHE n 
1 598 VAL n 
1 599 ASP n 
1 600 SER n 
1 601 ILE n 
1 602 ALA n 
1 603 GLY n 
1 604 MET n 
1 605 ASP n 
1 606 GLU n 
1 607 LEU n 
1 608 MET n 
1 609 GLU n 
1 610 VAL n 
1 611 SER n 
1 612 PHE n 
1 613 SER n 
1 614 PRO n 
1 615 LEU n 
1 616 ALA n 
1 617 ALA n 
1 618 THR n 
1 619 GLY n 
1 620 LYS n 
1 621 PRO n 
1 622 LEU n 
1 623 SER n 
1 624 ARG n 
1 625 CYS n 
1 626 GLY n 
1 627 LYS n 
1 628 CYS n 
1 629 HIS n 
1 630 ARG n 
1 631 PHE n 
1 632 MET n 
1 633 LYS n 
1 634 TYR n 
1 635 ILE n 
1 636 GLN n 
1 637 ALA n 
1 638 LYS n 
1 639 PRO n 
1 640 SER n 
1 641 ARG n 
1 642 LEU n 
1 643 HIS n 
1 644 CYS n 
1 645 SER n 
1 646 HIS n 
1 647 CYS n 
1 648 ASP n 
1 649 GLU n 
1 650 THR n 
1 651 TYR n 
1 652 THR n 
1 653 LEU n 
1 654 PRO n 
1 655 ASN n 
1 656 ASN n 
1 657 GLY n 
1 658 THR n 
1 659 ILE n 
1 660 LYS n 
1 661 LEU n 
1 662 TYR n 
1 663 LYS n 
1 664 GLU n 
1 665 LEU n 
1 666 ARG n 
1 667 CYS n 
1 668 PRO n 
1 669 LEU n 
1 670 ASP n 
1 671 ASP n 
1 672 PHE n 
1 673 GLU n 
1 674 LEU n 
1 675 VAL n 
1 676 LEU n 
1 677 TRP n 
1 678 SER n 
1 679 SER n 
1 680 GLY n 
1 681 SER n 
1 682 ARG n 
1 683 GLY n 
1 684 LYS n 
1 685 SER n 
1 686 TYR n 
1 687 PRO n 
1 688 LEU n 
1 689 CYS n 
1 690 PRO n 
1 691 TYR n 
1 692 CYS n 
1 693 TYR n 
1 694 ASN n 
1 695 HIS n 
1 696 PRO n 
1 697 PRO n 
1 698 PHE n 
1 699 ARG n 
1 700 ASP n 
1 701 MET n 
1 702 LYS n 
1 703 LYS n 
1 704 GLY n 
1 705 MET n 
1 706 GLY n 
1 707 CYS n 
1 708 ASN n 
1 709 GLU n 
1 710 CYS n 
1 711 THR n 
1 712 HIS n 
1 713 PRO n 
1 714 SER n 
1 715 CYS n 
1 716 GLN n 
1 717 HIS n 
1 718 SER n 
2 1   MET n 
2 2   ALA n 
2 3   GLN n 
2 4   VAL n 
2 5   ALA n 
2 6   GLY n 
2 7   ALA n 
2 8   ALA n 
2 9   LEU n 
2 10  SER n 
2 11  GLN n 
2 12  ALA n 
2 13  GLY n 
2 14  TRP n 
2 15  TYR n 
2 16  LEU n 
2 17  SER n 
2 18  ASP n 
2 19  GLU n 
2 20  GLY n 
2 21  ILE n 
2 22  GLU n 
2 23  ALA n 
2 24  CYS n 
2 25  THR n 
2 26  SER n 
2 27  SER n 
2 28  PRO n 
2 29  ASP n 
2 30  LYS n 
2 31  VAL n 
2 32  ASN n 
2 33  VAL n 
2 34  ASN n 
2 35  ASP n 
2 36  ILE n 
2 37  ILE n 
2 38  LEU n 
2 39  ILE n 
2 40  ALA n 
2 41  LEU n 
2 42  ASN n 
2 43  THR n 
2 44  ASP n 
2 45  LEU n 
2 46  ARG n 
2 47  THR n 
2 48  ILE n 
2 49  GLY n 
2 50  LYS n 
2 51  LYS n 
2 52  PHE n 
2 53  LEU n 
2 54  PRO n 
2 55  SER n 
2 56  ASP n 
2 57  ILE n 
2 58  ASN n 
2 59  SER n 
2 60  GLY n 
2 61  LYS n 
2 62  VAL n 
2 63  GLU n 
2 64  LYS n 
2 65  LEU n 
2 66  GLU n 
2 67  GLY n 
2 68  PRO n 
2 69  CYS n 
2 70  VAL n 
2 71  LEU n 
2 72  GLN n 
2 73  ILE n 
2 74  GLN n 
2 75  LYS n 
2 76  ILE n 
2 77  ARG n 
2 78  ASN n 
2 79  VAL n 
2 80  ALA n 
2 81  ALA n 
2 82  PRO n 
2 83  LYS n 
2 84  ASP n 
2 85  ASN n 
2 86  GLU n 
2 87  GLU n 
2 88  SER n 
2 89  GLN n 
2 90  ALA n 
2 91  ALA n 
2 92  PRO n 
2 93  ARG n 
2 94  MET n 
2 95  LEU n 
2 96  ARG n 
2 97  LEU n 
2 98  GLN n 
2 99  MET n 
2 100 THR n 
2 101 ASP n 
2 102 GLY n 
2 103 HIS n 
2 104 ILE n 
2 105 SER n 
2 106 CYS n 
2 107 THR n 
2 108 ALA n 
2 109 VAL n 
2 110 GLU n 
2 111 PHE n 
2 112 SER n 
2 113 TYR n 
2 114 MET n 
2 115 SER n 
2 116 LYS n 
2 117 ILE n 
2 118 SER n 
2 119 LEU n 
2 120 ASN n 
2 121 THR n 
2 122 PRO n 
2 123 PRO n 
2 124 GLY n 
2 125 THR n 
2 126 LYS n 
2 127 VAL n 
2 128 LYS n 
2 129 LEU n 
2 130 SER n 
2 131 GLY n 
2 132 ILE n 
2 133 VAL n 
2 134 ASP n 
2 135 ILE n 
2 136 LYS n 
2 137 ASN n 
2 138 GLY n 
2 139 PHE n 
2 140 LEU n 
2 141 LEU n 
2 142 LEU n 
2 143 ASN n 
2 144 ASP n 
2 145 SER n 
2 146 ASN n 
2 147 THR n 
2 148 THR n 
2 149 VAL n 
2 150 LEU n 
2 151 GLY n 
2 152 GLY n 
2 153 GLU n 
2 154 VAL n 
2 155 GLU n 
2 156 HIS n 
2 157 LEU n 
2 158 ILE n 
2 159 GLU n 
2 160 LYS n 
2 161 TRP n 
2 162 GLU n 
2 163 LEU n 
2 164 GLN n 
2 165 ARG n 
2 166 SER n 
2 167 LEU n 
2 168 SER n 
2 169 LYS n 
2 170 HIS n 
2 171 ASN n 
2 172 ARG n 
2 173 SER n 
2 174 ASN n 
2 175 ILE n 
2 176 GLY n 
2 177 THR n 
2 178 GLU n 
2 179 GLY n 
2 180 GLY n 
2 181 PRO n 
2 182 PRO n 
2 183 PRO n 
2 184 PHE n 
2 185 VAL n 
2 186 PRO n 
2 187 PHE n 
2 188 GLY n 
2 189 GLN n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 718 human ? 'TOP3B, TOP3B1' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? human 'Homo sapiens' 
9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 189 human ? TDRD3           ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? human 'Homo sapiens' 
9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE              ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE             ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE           ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'      ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE             ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE            ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'      ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE              ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE            ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE           ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE              ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE               ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE           ? 'C5 H11 N O2 S'  149.211 
MN  non-polymer         . 'MANGANESE (II) ION' ? 'Mn 2'           54.938  
PHE 'L-peptide linking' y PHENYLALANINE        ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE              ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE               ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE            ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN           ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE             ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE               ? 'C5 H11 N O2'    117.146 
ZN  non-polymer         . 'ZINC ION'           ? 'Zn 2'           65.409  
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   HIS 1   0   0   HIS HIS A . n 
A 1 2   MET 2   1   1   MET MET A . n 
A 1 3   LYS 3   2   2   LYS LYS A . n 
A 1 4   THR 4   3   3   THR THR A . n 
A 1 5   VAL 5   4   4   VAL VAL A . n 
A 1 6   LEU 6   5   5   LEU LEU A . n 
A 1 7   MET 7   6   6   MET MET A . n 
A 1 8   VAL 8   7   7   VAL VAL A . n 
A 1 9   ALA 9   8   8   ALA ALA A . n 
A 1 10  GLU 10  9   9   GLU GLU A . n 
A 1 11  LYS 11  10  10  LYS LYS A . n 
A 1 12  PRO 12  11  11  PRO PRO A . n 
A 1 13  SER 13  12  12  SER SER A . n 
A 1 14  LEU 14  13  13  LEU LEU A . n 
A 1 15  ALA 15  14  14  ALA ALA A . n 
A 1 16  GLN 16  15  15  GLN GLN A . n 
A 1 17  SER 17  16  16  SER SER A . n 
A 1 18  ILE 18  17  17  ILE ILE A . n 
A 1 19  ALA 19  18  18  ALA ALA A . n 
A 1 20  LYS 20  19  19  LYS LYS A . n 
A 1 21  ILE 21  20  20  ILE ILE A . n 
A 1 22  LEU 22  21  21  LEU LEU A . n 
A 1 23  SER 23  22  22  SER SER A . n 
A 1 24  ARG 24  23  23  ARG ARG A . n 
A 1 25  GLY 25  24  24  GLY GLY A . n 
A 1 26  SER 26  25  25  SER SER A . n 
A 1 27  LEU 27  26  26  LEU LEU A . n 
A 1 28  SER 28  27  27  SER SER A . n 
A 1 29  SER 29  28  28  SER SER A . n 
A 1 30  HIS 30  29  29  HIS HIS A . n 
A 1 31  LYS 31  30  30  LYS LYS A . n 
A 1 32  GLY 32  31  31  GLY GLY A . n 
A 1 33  LEU 33  32  32  LEU LEU A . n 
A 1 34  ASN 34  33  33  ASN ASN A . n 
A 1 35  GLY 35  34  34  GLY GLY A . n 
A 1 36  ALA 36  35  35  ALA ALA A . n 
A 1 37  CYS 37  36  36  CYS CYS A . n 
A 1 38  SER 38  37  37  SER SER A . n 
A 1 39  VAL 39  38  38  VAL VAL A . n 
A 1 40  HIS 40  39  39  HIS HIS A . n 
A 1 41  GLU 41  40  40  GLU GLU A . n 
A 1 42  TYR 42  41  41  TYR TYR A . n 
A 1 43  THR 43  42  42  THR THR A . n 
A 1 44  GLY 44  43  43  GLY GLY A . n 
A 1 45  THR 45  44  44  THR THR A . n 
A 1 46  PHE 46  45  45  PHE PHE A . n 
A 1 47  ALA 47  46  46  ALA ALA A . n 
A 1 48  GLY 48  47  47  GLY GLY A . n 
A 1 49  GLN 49  48  48  GLN GLN A . n 
A 1 50  PRO 50  49  49  PRO PRO A . n 
A 1 51  VAL 51  50  50  VAL VAL A . n 
A 1 52  ARG 52  51  51  ARG ARG A . n 
A 1 53  PHE 53  52  52  PHE PHE A . n 
A 1 54  LYS 54  53  53  LYS LYS A . n 
A 1 55  MET 55  54  54  MET MET A . n 
A 1 56  THR 56  55  55  THR THR A . n 
A 1 57  SER 57  56  56  SER SER A . n 
A 1 58  VAL 58  57  57  VAL VAL A . n 
A 1 59  CYS 59  58  58  CYS CYS A . n 
A 1 60  GLY 60  59  59  GLY GLY A . n 
A 1 61  HIS 61  60  60  HIS HIS A . n 
A 1 62  VAL 62  61  61  VAL VAL A . n 
A 1 63  MET 63  62  62  MET MET A . n 
A 1 64  THR 64  63  63  THR THR A . n 
A 1 65  LEU 65  64  64  LEU LEU A . n 
A 1 66  ASP 66  65  65  ASP ASP A . n 
A 1 67  PHE 67  66  66  PHE PHE A . n 
A 1 68  LEU 68  67  67  LEU LEU A . n 
A 1 69  GLY 69  68  68  GLY GLY A . n 
A 1 70  LYS 70  69  69  LYS LYS A . n 
A 1 71  TYR 71  70  70  TYR TYR A . n 
A 1 72  ASN 72  71  71  ASN ASN A . n 
A 1 73  LYS 73  72  72  LYS LYS A . n 
A 1 74  TRP 74  73  73  TRP TRP A . n 
A 1 75  ASP 75  74  74  ASP ASP A . n 
A 1 76  LYS 76  75  75  LYS LYS A . n 
A 1 77  VAL 77  76  76  VAL VAL A . n 
A 1 78  ASP 78  77  77  ASP ASP A . n 
A 1 79  PRO 79  78  78  PRO PRO A . n 
A 1 80  ALA 80  79  79  ALA ALA A . n 
A 1 81  GLU 81  80  80  GLU GLU A . n 
A 1 82  LEU 82  81  81  LEU LEU A . n 
A 1 83  PHE 83  82  82  PHE PHE A . n 
A 1 84  SER 84  83  83  SER SER A . n 
A 1 85  GLN 85  84  84  GLN GLN A . n 
A 1 86  ALA 86  85  85  ALA ALA A . n 
A 1 87  PRO 87  86  86  PRO PRO A . n 
A 1 88  THR 88  87  87  THR THR A . n 
A 1 89  GLU 89  88  88  GLU GLU A . n 
A 1 90  LYS 90  89  89  LYS LYS A . n 
A 1 91  LYS 91  90  90  LYS LYS A . n 
A 1 92  GLU 92  91  91  GLU GLU A . n 
A 1 93  ALA 93  92  92  ALA ALA A . n 
A 1 94  ASN 94  93  93  ASN ASN A . n 
A 1 95  PRO 95  94  94  PRO PRO A . n 
A 1 96  LYS 96  95  95  LYS LYS A . n 
A 1 97  LEU 97  96  96  LEU LEU A . n 
A 1 98  ASN 98  97  97  ASN ASN A . n 
A 1 99  MET 99  98  98  MET MET A . n 
A 1 100 VAL 100 99  99  VAL VAL A . n 
A 1 101 LYS 101 100 100 LYS LYS A . n 
A 1 102 PHE 102 101 101 PHE PHE A . n 
A 1 103 LEU 103 102 102 LEU LEU A . n 
A 1 104 GLN 104 103 103 GLN GLN A . n 
A 1 105 VAL 105 104 104 VAL VAL A . n 
A 1 106 GLU 106 105 105 GLU GLU A . n 
A 1 107 GLY 107 106 106 GLY GLY A . n 
A 1 108 ARG 108 107 107 ARG ARG A . n 
A 1 109 GLY 109 108 108 GLY GLY A . n 
A 1 110 CYS 110 109 109 CYS CYS A . n 
A 1 111 ASP 111 110 110 ASP ASP A . n 
A 1 112 TYR 112 111 111 TYR TYR A . n 
A 1 113 ILE 113 112 112 ILE ILE A . n 
A 1 114 VAL 114 113 113 VAL VAL A . n 
A 1 115 LEU 115 114 114 LEU LEU A . n 
A 1 116 TRP 116 115 115 TRP TRP A . n 
A 1 117 LEU 117 116 116 LEU LEU A . n 
A 1 118 ASP 118 117 117 ASP ASP A . n 
A 1 119 CYS 119 118 118 CYS CYS A . n 
A 1 120 ASP 120 119 119 ASP ASP A . n 
A 1 121 LYS 121 120 120 LYS LYS A . n 
A 1 122 GLU 122 121 121 GLU GLU A . n 
A 1 123 GLY 123 122 122 GLY GLY A . n 
A 1 124 GLU 124 123 123 GLU GLU A . n 
A 1 125 ASN 125 124 124 ASN ASN A . n 
A 1 126 ILE 126 125 125 ILE ILE A . n 
A 1 127 CYS 127 126 126 CYS CYS A . n 
A 1 128 PHE 128 127 127 PHE PHE A . n 
A 1 129 GLU 129 128 128 GLU GLU A . n 
A 1 130 VAL 130 129 129 VAL VAL A . n 
A 1 131 LEU 131 130 130 LEU LEU A . n 
A 1 132 ASP 132 131 131 ASP ASP A . n 
A 1 133 ALA 133 132 132 ALA ALA A . n 
A 1 134 VAL 134 133 133 VAL VAL A . n 
A 1 135 LEU 135 134 134 LEU LEU A . n 
A 1 136 PRO 136 135 135 PRO PRO A . n 
A 1 137 VAL 137 136 136 VAL VAL A . n 
A 1 138 MET 138 137 137 MET MET A . n 
A 1 139 ASN 139 138 138 ASN ASN A . n 
A 1 140 LYS 140 139 139 LYS LYS A . n 
A 1 141 ALA 141 140 140 ALA ALA A . n 
A 1 142 HIS 142 141 141 HIS HIS A . n 
A 1 143 GLY 143 142 142 GLY GLY A . n 
A 1 144 GLY 144 143 143 GLY GLY A . n 
A 1 145 GLU 145 144 144 GLU GLU A . n 
A 1 146 LYS 146 145 145 LYS LYS A . n 
A 1 147 THR 147 146 146 THR THR A . n 
A 1 148 VAL 148 147 147 VAL VAL A . n 
A 1 149 PHE 149 148 148 PHE PHE A . n 
A 1 150 ARG 150 149 149 ARG ARG A . n 
A 1 151 ALA 151 150 150 ALA ALA A . n 
A 1 152 ARG 152 151 151 ARG ARG A . n 
A 1 153 PHE 153 152 152 PHE PHE A . n 
A 1 154 SER 154 153 153 SER SER A . n 
A 1 155 SER 155 154 154 SER SER A . n 
A 1 156 ILE 156 155 155 ILE ILE A . n 
A 1 157 THR 157 156 156 THR THR A . n 
A 1 158 ASP 158 157 157 ASP ASP A . n 
A 1 159 THR 159 158 158 THR THR A . n 
A 1 160 ASP 160 159 159 ASP ASP A . n 
A 1 161 ILE 161 160 160 ILE ILE A . n 
A 1 162 CYS 162 161 161 CYS CYS A . n 
A 1 163 ASN 163 162 162 ASN ASN A . n 
A 1 164 ALA 164 163 163 ALA ALA A . n 
A 1 165 MET 165 164 164 MET MET A . n 
A 1 166 ALA 166 165 165 ALA ALA A . n 
A 1 167 CYS 167 166 166 CYS CYS A . n 
A 1 168 LEU 168 167 167 LEU LEU A . n 
A 1 169 GLY 169 168 168 GLY GLY A . n 
A 1 170 GLU 170 169 169 GLU GLU A . n 
A 1 171 PRO 171 170 170 PRO PRO A . n 
A 1 172 ASP 172 171 171 ASP ASP A . n 
A 1 173 HIS 173 172 172 HIS HIS A . n 
A 1 174 ASN 174 173 173 ASN ASN A . n 
A 1 175 GLU 175 174 174 GLU GLU A . n 
A 1 176 ALA 176 175 175 ALA ALA A . n 
A 1 177 LEU 177 176 176 LEU LEU A . n 
A 1 178 SER 178 177 177 SER SER A . n 
A 1 179 VAL 179 178 178 VAL VAL A . n 
A 1 180 ASP 180 179 179 ASP ASP A . n 
A 1 181 ALA 181 180 180 ALA ALA A . n 
A 1 182 ARG 182 181 181 ARG ARG A . n 
A 1 183 GLN 183 182 182 GLN GLN A . n 
A 1 184 GLU 184 183 183 GLU GLU A . n 
A 1 185 LEU 185 184 184 LEU LEU A . n 
A 1 186 ASP 186 185 185 ASP ASP A . n 
A 1 187 LEU 187 186 186 LEU LEU A . n 
A 1 188 ARG 188 187 187 ARG ARG A . n 
A 1 189 ILE 189 188 188 ILE ILE A . n 
A 1 190 GLY 190 189 189 GLY GLY A . n 
A 1 191 CYS 191 190 190 CYS CYS A . n 
A 1 192 ALA 192 191 191 ALA ALA A . n 
A 1 193 PHE 193 192 192 PHE PHE A . n 
A 1 194 THR 194 193 193 THR THR A . n 
A 1 195 ARG 195 194 194 ARG ARG A . n 
A 1 196 PHE 196 195 195 PHE PHE A . n 
A 1 197 GLN 197 196 196 GLN GLN A . n 
A 1 198 THR 198 197 197 THR THR A . n 
A 1 199 LYS 199 198 198 LYS LYS A . n 
A 1 200 TYR 200 199 199 TYR TYR A . n 
A 1 201 PHE 201 200 200 PHE PHE A . n 
A 1 202 GLN 202 201 201 GLN GLN A . n 
A 1 203 GLY 203 202 202 GLY GLY A . n 
A 1 204 LYS 204 203 203 LYS LYS A . n 
A 1 205 TYR 205 204 204 TYR TYR A . n 
A 1 206 GLY 206 205 205 GLY GLY A . n 
A 1 207 ASP 207 206 206 ASP ASP A . n 
A 1 208 LEU 208 207 207 LEU LEU A . n 
A 1 209 ASP 209 208 208 ASP ASP A . n 
A 1 210 SER 210 209 209 SER SER A . n 
A 1 211 SER 211 210 210 SER SER A . n 
A 1 212 LEU 212 211 211 LEU LEU A . n 
A 1 213 ILE 213 212 212 ILE ILE A . n 
A 1 214 SER 214 213 213 SER SER A . n 
A 1 215 PHE 215 214 214 PHE PHE A . n 
A 1 216 GLY 216 215 215 GLY GLY A . n 
A 1 217 PRO 217 216 216 PRO PRO A . n 
A 1 218 CYS 218 217 217 CYS CYS A . n 
A 1 219 GLN 219 218 218 GLN GLN A . n 
A 1 220 THR 220 219 219 THR THR A . n 
A 1 221 PRO 221 220 220 PRO PRO A . n 
A 1 222 THR 222 221 221 THR THR A . n 
A 1 223 LEU 223 222 222 LEU LEU A . n 
A 1 224 GLY 224 223 223 GLY GLY A . n 
A 1 225 PHE 225 224 224 PHE PHE A . n 
A 1 226 CYS 226 225 225 CYS CYS A . n 
A 1 227 VAL 227 226 226 VAL VAL A . n 
A 1 228 GLU 228 227 227 GLU GLU A . n 
A 1 229 ARG 229 228 228 ARG ARG A . n 
A 1 230 HIS 230 229 229 HIS HIS A . n 
A 1 231 ASP 231 230 230 ASP ASP A . n 
A 1 232 LYS 232 231 231 LYS LYS A . n 
A 1 233 ILE 233 232 232 ILE ILE A . n 
A 1 234 GLN 234 233 233 GLN GLN A . n 
A 1 235 SER 235 234 234 SER SER A . n 
A 1 236 PHE 236 235 235 PHE PHE A . n 
A 1 237 LYS 237 236 236 LYS LYS A . n 
A 1 238 PRO 238 237 237 PRO PRO A . n 
A 1 239 GLU 239 238 238 GLU GLU A . n 
A 1 240 THR 240 239 239 THR THR A . n 
A 1 241 TYR 241 240 240 TYR TYR A . n 
A 1 242 TRP 242 241 241 TRP TRP A . n 
A 1 243 VAL 243 242 242 VAL VAL A . n 
A 1 244 LEU 244 243 243 LEU LEU A . n 
A 1 245 GLN 245 244 244 GLN GLN A . n 
A 1 246 ALA 246 245 245 ALA ALA A . n 
A 1 247 LYS 247 246 246 LYS LYS A . n 
A 1 248 VAL 248 247 247 VAL VAL A . n 
A 1 249 ASN 249 248 248 ASN ASN A . n 
A 1 250 THR 250 249 249 THR THR A . n 
A 1 251 ASP 251 250 250 ASP ASP A . n 
A 1 252 LYS 252 251 251 LYS LYS A . n 
A 1 253 ASP 253 252 252 ASP ASP A . n 
A 1 254 ARG 254 253 253 ARG ARG A . n 
A 1 255 SER 255 254 254 SER SER A . n 
A 1 256 LEU 256 255 255 LEU LEU A . n 
A 1 257 LEU 257 256 256 LEU LEU A . n 
A 1 258 LEU 258 257 257 LEU LEU A . n 
A 1 259 ASP 259 258 258 ASP ASP A . n 
A 1 260 TRP 260 259 259 TRP TRP A . n 
A 1 261 ASP 261 260 260 ASP ASP A . n 
A 1 262 ARG 262 261 261 ARG ARG A . n 
A 1 263 VAL 263 262 262 VAL VAL A . n 
A 1 264 ARG 264 263 263 ARG ARG A . n 
A 1 265 VAL 265 264 264 VAL VAL A . n 
A 1 266 PHE 266 265 265 PHE PHE A . n 
A 1 267 ASP 267 266 266 ASP ASP A . n 
A 1 268 ARG 268 267 267 ARG ARG A . n 
A 1 269 GLU 269 268 268 GLU GLU A . n 
A 1 270 ILE 270 269 269 ILE ILE A . n 
A 1 271 ALA 271 270 270 ALA ALA A . n 
A 1 272 GLN 272 271 271 GLN GLN A . n 
A 1 273 MET 273 272 272 MET MET A . n 
A 1 274 PHE 274 273 273 PHE PHE A . n 
A 1 275 LEU 275 274 274 LEU LEU A . n 
A 1 276 ASN 276 275 275 ASN ASN A . n 
A 1 277 MET 277 276 276 MET MET A . n 
A 1 278 THR 278 277 277 THR THR A . n 
A 1 279 LYS 279 278 278 LYS LYS A . n 
A 1 280 LEU 280 279 279 LEU LEU A . n 
A 1 281 GLU 281 280 280 GLU GLU A . n 
A 1 282 LYS 282 281 281 LYS LYS A . n 
A 1 283 GLU 283 282 282 GLU GLU A . n 
A 1 284 ALA 284 283 283 ALA ALA A . n 
A 1 285 GLN 285 284 284 GLN GLN A . n 
A 1 286 VAL 286 285 285 VAL VAL A . n 
A 1 287 GLU 287 286 286 GLU GLU A . n 
A 1 288 ALA 288 287 287 ALA ALA A . n 
A 1 289 THR 289 288 288 THR THR A . n 
A 1 290 SER 290 289 289 SER SER A . n 
A 1 291 ARG 291 290 290 ARG ARG A . n 
A 1 292 LYS 292 291 291 LYS LYS A . n 
A 1 293 GLU 293 292 292 GLU GLU A . n 
A 1 294 LYS 294 293 293 LYS LYS A . n 
A 1 295 ALA 295 294 294 ALA ALA A . n 
A 1 296 LYS 296 295 295 LYS LYS A . n 
A 1 297 GLN 297 296 296 GLN GLN A . n 
A 1 298 ARG 298 297 297 ARG ARG A . n 
A 1 299 PRO 299 298 298 PRO PRO A . n 
A 1 300 LEU 300 299 299 LEU LEU A . n 
A 1 301 ALA 301 300 300 ALA ALA A . n 
A 1 302 LEU 302 301 301 LEU LEU A . n 
A 1 303 ASN 303 302 302 ASN ASN A . n 
A 1 304 THR 304 303 303 THR THR A . n 
A 1 305 VAL 305 304 304 VAL VAL A . n 
A 1 306 GLU 306 305 305 GLU GLU A . n 
A 1 307 MET 307 306 306 MET MET A . n 
A 1 308 LEU 308 307 307 LEU LEU A . n 
A 1 309 ARG 309 308 308 ARG ARG A . n 
A 1 310 VAL 310 309 309 VAL VAL A . n 
A 1 311 ALA 311 310 310 ALA ALA A . n 
A 1 312 SER 312 311 311 SER SER A . n 
A 1 313 SER 313 312 312 SER SER A . n 
A 1 314 SER 314 313 313 SER SER A . n 
A 1 315 LEU 315 314 314 LEU LEU A . n 
A 1 316 GLY 316 315 315 GLY GLY A . n 
A 1 317 MET 317 316 316 MET MET A . n 
A 1 318 GLY 318 317 317 GLY GLY A . n 
A 1 319 PRO 319 318 318 PRO PRO A . n 
A 1 320 GLN 320 319 319 GLN GLN A . n 
A 1 321 HIS 321 320 320 HIS HIS A . n 
A 1 322 ALA 322 321 321 ALA ALA A . n 
A 1 323 MET 323 322 322 MET MET A . n 
A 1 324 GLN 324 323 323 GLN GLN A . n 
A 1 325 THR 325 324 324 THR THR A . n 
A 1 326 ALA 326 325 325 ALA ALA A . n 
A 1 327 GLU 327 326 326 GLU GLU A . n 
A 1 328 ARG 328 327 327 ARG ARG A . n 
A 1 329 LEU 329 328 328 LEU LEU A . n 
A 1 330 TYR 330 329 329 TYR TYR A . n 
A 1 331 THR 331 330 330 THR THR A . n 
A 1 332 GLN 332 331 331 GLN GLN A . n 
A 1 333 GLY 333 332 332 GLY GLY A . n 
A 1 334 TYR 334 333 333 TYR TYR A . n 
A 1 335 ILE 335 334 334 ILE ILE A . n 
A 1 336 SER 336 335 335 SER SER A . n 
A 1 337 TYR 337 336 336 TYR TYR A . n 
A 1 338 PRO 338 337 337 PRO PRO A . n 
A 1 339 ARG 339 338 338 ARG ARG A . n 
A 1 340 THR 340 339 339 THR THR A . n 
A 1 341 GLU 341 340 340 GLU GLU A . n 
A 1 342 THR 342 341 341 THR THR A . n 
A 1 343 THR 343 342 342 THR THR A . n 
A 1 344 HIS 344 343 343 HIS HIS A . n 
A 1 345 TYR 345 344 344 TYR TYR A . n 
A 1 346 PRO 346 345 345 PRO PRO A . n 
A 1 347 GLU 347 346 346 GLU GLU A . n 
A 1 348 ASN 348 347 347 ASN ASN A . n 
A 1 349 PHE 349 348 348 PHE PHE A . n 
A 1 350 ASP 350 349 349 ASP ASP A . n 
A 1 351 LEU 351 350 350 LEU LEU A . n 
A 1 352 LYS 352 351 351 LYS LYS A . n 
A 1 353 GLY 353 352 352 GLY GLY A . n 
A 1 354 SER 354 353 353 SER SER A . n 
A 1 355 LEU 355 354 354 LEU LEU A . n 
A 1 356 ARG 356 355 355 ARG ARG A . n 
A 1 357 GLN 357 356 356 GLN GLN A . n 
A 1 358 GLN 358 357 357 GLN GLN A . n 
A 1 359 ALA 359 358 358 ALA ALA A . n 
A 1 360 ASN 360 359 359 ASN ASN A . n 
A 1 361 HIS 361 360 360 HIS HIS A . n 
A 1 362 PRO 362 361 361 PRO PRO A . n 
A 1 363 TYR 363 362 362 TYR TYR A . n 
A 1 364 TRP 364 363 363 TRP TRP A . n 
A 1 365 ALA 365 364 364 ALA ALA A . n 
A 1 366 ASP 366 365 365 ASP ASP A . n 
A 1 367 THR 367 366 366 THR THR A . n 
A 1 368 VAL 368 367 367 VAL VAL A . n 
A 1 369 LYS 369 368 368 LYS LYS A . n 
A 1 370 ARG 370 369 369 ARG ARG A . n 
A 1 371 LEU 371 370 370 LEU LEU A . n 
A 1 372 LEU 372 371 371 LEU LEU A . n 
A 1 373 ALA 373 372 372 ALA ALA A . n 
A 1 374 GLU 374 373 373 GLU GLU A . n 
A 1 375 GLY 375 374 374 GLY GLY A . n 
A 1 376 ILE 376 375 375 ILE ILE A . n 
A 1 377 ASN 377 376 376 ASN ASN A . n 
A 1 378 ARG 378 377 377 ARG ARG A . n 
A 1 379 PRO 379 378 378 PRO PRO A . n 
A 1 380 ARG 380 379 379 ARG ARG A . n 
A 1 381 LYS 381 380 380 LYS LYS A . n 
A 1 382 GLY 382 381 381 GLY GLY A . n 
A 1 383 HIS 383 382 382 HIS HIS A . n 
A 1 384 ASP 384 383 383 ASP ASP A . n 
A 1 385 ALA 385 384 384 ALA ALA A . n 
A 1 386 GLY 386 385 385 GLY GLY A . n 
A 1 387 ASP 387 386 386 ASP ASP A . n 
A 1 388 HIS 388 387 387 HIS HIS A . n 
A 1 389 PRO 389 388 388 PRO PRO A . n 
A 1 390 PRO 390 389 389 PRO PRO A . n 
A 1 391 ILE 391 390 390 ILE ILE A . n 
A 1 392 THR 392 391 391 THR THR A . n 
A 1 393 PRO 393 392 392 PRO PRO A . n 
A 1 394 MET 394 393 393 MET MET A . n 
A 1 395 LYS 395 394 394 LYS LYS A . n 
A 1 396 SER 396 395 395 SER SER A . n 
A 1 397 ALA 397 396 396 ALA ALA A . n 
A 1 398 THR 398 397 397 THR THR A . n 
A 1 399 GLU 399 398 398 GLU GLU A . n 
A 1 400 ALA 400 399 399 ALA ALA A . n 
A 1 401 GLU 401 400 400 GLU GLU A . n 
A 1 402 LEU 402 401 401 LEU LEU A . n 
A 1 403 GLY 403 402 402 GLY GLY A . n 
A 1 404 GLY 404 403 403 GLY GLY A . n 
A 1 405 ASP 405 404 404 ASP ASP A . n 
A 1 406 ALA 406 405 405 ALA ALA A . n 
A 1 407 TRP 407 406 406 TRP TRP A . n 
A 1 408 ARG 408 407 407 ARG ARG A . n 
A 1 409 LEU 409 408 408 LEU LEU A . n 
A 1 410 TYR 410 409 409 TYR TYR A . n 
A 1 411 GLU 411 410 410 GLU GLU A . n 
A 1 412 TYR 412 411 411 TYR TYR A . n 
A 1 413 ILE 413 412 412 ILE ILE A . n 
A 1 414 THR 414 413 413 THR THR A . n 
A 1 415 ARG 415 414 414 ARG ARG A . n 
A 1 416 HIS 416 415 415 HIS HIS A . n 
A 1 417 PHE 417 416 416 PHE PHE A . n 
A 1 418 ILE 418 417 417 ILE ILE A . n 
A 1 419 ALA 419 418 418 ALA ALA A . n 
A 1 420 THR 420 419 419 THR THR A . n 
A 1 421 VAL 421 420 420 VAL VAL A . n 
A 1 422 SER 422 421 421 SER SER A . n 
A 1 423 HIS 423 422 422 HIS HIS A . n 
A 1 424 ASP 424 423 423 ASP ASP A . n 
A 1 425 CYS 425 424 424 CYS CYS A . n 
A 1 426 LYS 426 425 425 LYS LYS A . n 
A 1 427 TYR 427 426 426 TYR TYR A . n 
A 1 428 LEU 428 427 427 LEU LEU A . n 
A 1 429 GLN 429 428 428 GLN GLN A . n 
A 1 430 SER 430 429 429 SER SER A . n 
A 1 431 THR 431 430 430 THR THR A . n 
A 1 432 ILE 432 431 431 ILE ILE A . n 
A 1 433 SER 433 432 432 SER SER A . n 
A 1 434 PHE 434 433 433 PHE PHE A . n 
A 1 435 ARG 435 434 434 ARG ARG A . n 
A 1 436 ILE 436 435 435 ILE ILE A . n 
A 1 437 GLY 437 436 436 GLY GLY A . n 
A 1 438 PRO 438 437 437 PRO PRO A . n 
A 1 439 GLU 439 438 438 GLU GLU A . n 
A 1 440 LEU 440 439 439 LEU LEU A . n 
A 1 441 PHE 441 440 440 PHE PHE A . n 
A 1 442 THR 442 441 441 THR THR A . n 
A 1 443 CYS 443 442 442 CYS CYS A . n 
A 1 444 SER 444 443 443 SER SER A . n 
A 1 445 GLY 445 444 444 GLY GLY A . n 
A 1 446 LYS 446 445 445 LYS LYS A . n 
A 1 447 THR 447 446 446 THR THR A . n 
A 1 448 VAL 448 447 447 VAL VAL A . n 
A 1 449 LEU 449 448 448 LEU LEU A . n 
A 1 450 SER 450 449 449 SER SER A . n 
A 1 451 PRO 451 450 450 PRO PRO A . n 
A 1 452 GLY 452 451 451 GLY GLY A . n 
A 1 453 PHE 453 452 452 PHE PHE A . n 
A 1 454 THR 454 453 453 THR THR A . n 
A 1 455 GLU 455 454 454 GLU GLU A . n 
A 1 456 VAL 456 455 455 VAL VAL A . n 
A 1 457 MET 457 456 456 MET MET A . n 
A 1 458 PRO 458 457 457 PRO PRO A . n 
A 1 459 TRP 459 458 458 TRP TRP A . n 
A 1 460 GLN 460 459 459 GLN GLN A . n 
A 1 461 SER 461 460 460 SER SER A . n 
A 1 462 VAL 462 461 461 VAL VAL A . n 
A 1 463 PRO 463 462 462 PRO PRO A . n 
A 1 464 LEU 464 463 463 LEU LEU A . n 
A 1 465 GLU 465 464 464 GLU GLU A . n 
A 1 466 GLU 466 465 465 GLU GLU A . n 
A 1 467 SER 467 466 466 SER SER A . n 
A 1 468 LEU 468 467 467 LEU LEU A . n 
A 1 469 PRO 469 468 468 PRO PRO A . n 
A 1 470 THR 470 469 469 THR THR A . n 
A 1 471 CYS 471 470 470 CYS CYS A . n 
A 1 472 GLN 472 471 471 GLN GLN A . n 
A 1 473 ARG 473 472 472 ARG ARG A . n 
A 1 474 GLY 474 473 473 GLY GLY A . n 
A 1 475 ASP 475 474 474 ASP ASP A . n 
A 1 476 ALA 476 475 475 ALA ALA A . n 
A 1 477 PHE 477 476 476 PHE PHE A . n 
A 1 478 PRO 478 477 477 PRO PRO A . n 
A 1 479 VAL 479 478 478 VAL VAL A . n 
A 1 480 GLY 480 479 479 GLY GLY A . n 
A 1 481 GLU 481 480 480 GLU GLU A . n 
A 1 482 VAL 482 481 481 VAL VAL A . n 
A 1 483 LYS 483 482 482 LYS LYS A . n 
A 1 484 MET 484 483 483 MET MET A . n 
A 1 485 LEU 485 484 484 LEU LEU A . n 
A 1 486 GLU 486 485 485 GLU GLU A . n 
A 1 487 LYS 487 486 486 LYS LYS A . n 
A 1 488 GLN 488 487 487 GLN GLN A . n 
A 1 489 THR 489 488 488 THR THR A . n 
A 1 490 ASN 490 489 489 ASN ASN A . n 
A 1 491 PRO 491 490 490 PRO PRO A . n 
A 1 492 PRO 492 491 491 PRO PRO A . n 
A 1 493 ASP 493 492 492 ASP ASP A . n 
A 1 494 TYR 494 493 493 TYR TYR A . n 
A 1 495 LEU 495 494 494 LEU LEU A . n 
A 1 496 THR 496 495 495 THR THR A . n 
A 1 497 GLU 497 496 496 GLU GLU A . n 
A 1 498 ALA 498 497 497 ALA ALA A . n 
A 1 499 GLU 499 498 498 GLU GLU A . n 
A 1 500 LEU 500 499 499 LEU LEU A . n 
A 1 501 ILE 501 500 500 ILE ILE A . n 
A 1 502 THR 502 501 501 THR THR A . n 
A 1 503 LEU 503 502 502 LEU LEU A . n 
A 1 504 MET 504 503 503 MET MET A . n 
A 1 505 GLU 505 504 504 GLU GLU A . n 
A 1 506 LYS 506 505 505 LYS LYS A . n 
A 1 507 HIS 507 506 506 HIS HIS A . n 
A 1 508 GLY 508 507 507 GLY GLY A . n 
A 1 509 ILE 509 508 508 ILE ILE A . n 
A 1 510 GLY 510 509 509 GLY GLY A . n 
A 1 511 THR 511 510 510 THR THR A . n 
A 1 512 ASP 512 511 511 ASP ASP A . n 
A 1 513 ALA 513 512 512 ALA ALA A . n 
A 1 514 SER 514 513 513 SER SER A . n 
A 1 515 ILE 515 514 514 ILE ILE A . n 
A 1 516 PRO 516 515 515 PRO PRO A . n 
A 1 517 VAL 517 516 516 VAL VAL A . n 
A 1 518 HIS 518 517 517 HIS HIS A . n 
A 1 519 ILE 519 518 518 ILE ILE A . n 
A 1 520 ASN 520 519 519 ASN ASN A . n 
A 1 521 ASN 521 520 520 ASN ASN A . n 
A 1 522 ILE 522 521 521 ILE ILE A . n 
A 1 523 CYS 523 522 522 CYS CYS A . n 
A 1 524 GLN 524 523 523 GLN GLN A . n 
A 1 525 ARG 525 524 524 ARG ARG A . n 
A 1 526 ASN 526 525 525 ASN ASN A . n 
A 1 527 TYR 527 526 526 TYR TYR A . n 
A 1 528 VAL 528 527 527 VAL VAL A . n 
A 1 529 THR 529 528 528 THR THR A . n 
A 1 530 VAL 530 529 529 VAL VAL A . n 
A 1 531 GLU 531 530 530 GLU GLU A . n 
A 1 532 SER 532 531 531 SER SER A . n 
A 1 533 GLY 533 532 532 GLY GLY A . n 
A 1 534 ARG 534 533 533 ARG ARG A . n 
A 1 535 ARG 535 534 534 ARG ARG A . n 
A 1 536 LEU 536 535 535 LEU LEU A . n 
A 1 537 LYS 537 536 536 LYS LYS A . n 
A 1 538 PRO 538 537 537 PRO PRO A . n 
A 1 539 THR 539 538 538 THR THR A . n 
A 1 540 ASN 540 539 539 ASN ASN A . n 
A 1 541 LEU 541 540 540 LEU LEU A . n 
A 1 542 GLY 542 541 541 GLY GLY A . n 
A 1 543 ILE 543 542 542 ILE ILE A . n 
A 1 544 VAL 544 543 543 VAL VAL A . n 
A 1 545 LEU 545 544 544 LEU LEU A . n 
A 1 546 VAL 546 545 545 VAL VAL A . n 
A 1 547 HIS 547 546 546 HIS HIS A . n 
A 1 548 GLY 548 547 547 GLY GLY A . n 
A 1 549 TYR 549 548 548 TYR TYR A . n 
A 1 550 TYR 550 549 549 TYR TYR A . n 
A 1 551 LYS 551 550 550 LYS LYS A . n 
A 1 552 ILE 552 551 551 ILE ILE A . n 
A 1 553 ASP 553 552 552 ASP ASP A . n 
A 1 554 ALA 554 553 553 ALA ALA A . n 
A 1 555 GLU 555 554 554 GLU GLU A . n 
A 1 556 LEU 556 555 555 LEU LEU A . n 
A 1 557 VAL 557 556 556 VAL VAL A . n 
A 1 558 LEU 558 557 557 LEU LEU A . n 
A 1 559 PRO 559 558 558 PRO PRO A . n 
A 1 560 THR 560 559 559 THR THR A . n 
A 1 561 ILE 561 560 560 ILE ILE A . n 
A 1 562 ARG 562 561 561 ARG ARG A . n 
A 1 563 SER 563 562 562 SER SER A . n 
A 1 564 ALA 564 563 563 ALA ALA A . n 
A 1 565 VAL 565 564 564 VAL VAL A . n 
A 1 566 GLU 566 565 565 GLU GLU A . n 
A 1 567 LYS 567 566 566 LYS LYS A . n 
A 1 568 GLN 568 567 567 GLN GLN A . n 
A 1 569 LEU 569 568 568 LEU LEU A . n 
A 1 570 ASN 570 569 569 ASN ASN A . n 
A 1 571 LEU 571 570 570 LEU LEU A . n 
A 1 572 ILE 572 571 571 ILE ILE A . n 
A 1 573 ALA 573 572 572 ALA ALA A . n 
A 1 574 GLN 574 573 573 GLN GLN A . n 
A 1 575 GLY 575 574 574 GLY GLY A . n 
A 1 576 LYS 576 575 575 LYS LYS A . n 
A 1 577 ALA 577 576 576 ALA ALA A . n 
A 1 578 ASP 578 577 577 ASP ASP A . n 
A 1 579 TYR 579 578 578 TYR TYR A . n 
A 1 580 ARG 580 579 579 ARG ARG A . n 
A 1 581 GLN 581 580 580 GLN GLN A . n 
A 1 582 VAL 582 581 581 VAL VAL A . n 
A 1 583 LEU 583 582 582 LEU LEU A . n 
A 1 584 GLY 584 583 583 GLY GLY A . n 
A 1 585 HIS 585 584 584 HIS HIS A . n 
A 1 586 THR 586 585 585 THR THR A . n 
A 1 587 LEU 587 586 586 LEU LEU A . n 
A 1 588 ASP 588 587 587 ASP ASP A . n 
A 1 589 VAL 589 588 588 VAL VAL A . n 
A 1 590 PHE 590 589 589 PHE PHE A . n 
A 1 591 LYS 591 590 590 LYS LYS A . n 
A 1 592 ARG 592 591 591 ARG ARG A . n 
A 1 593 LYS 593 592 592 LYS LYS A . n 
A 1 594 PHE 594 593 593 PHE PHE A . n 
A 1 595 HIS 595 594 594 HIS HIS A . n 
A 1 596 TYR 596 595 595 TYR TYR A . n 
A 1 597 PHE 597 596 596 PHE PHE A . n 
A 1 598 VAL 598 597 597 VAL VAL A . n 
A 1 599 ASP 599 598 598 ASP ASP A . n 
A 1 600 SER 600 599 599 SER SER A . n 
A 1 601 ILE 601 600 600 ILE ILE A . n 
A 1 602 ALA 602 601 601 ALA ALA A . n 
A 1 603 GLY 603 602 602 GLY GLY A . n 
A 1 604 MET 604 603 603 MET MET A . n 
A 1 605 ASP 605 604 604 ASP ASP A . n 
A 1 606 GLU 606 605 605 GLU GLU A . n 
A 1 607 LEU 607 606 606 LEU LEU A . n 
A 1 608 MET 608 607 607 MET MET A . n 
A 1 609 GLU 609 608 608 GLU GLU A . n 
A 1 610 VAL 610 609 609 VAL VAL A . n 
A 1 611 SER 611 610 610 SER SER A . n 
A 1 612 PHE 612 611 611 PHE PHE A . n 
A 1 613 SER 613 612 612 SER SER A . n 
A 1 614 PRO 614 613 613 PRO PRO A . n 
A 1 615 LEU 615 614 614 LEU LEU A . n 
A 1 616 ALA 616 615 615 ALA ALA A . n 
A 1 617 ALA 617 616 616 ALA ALA A . n 
A 1 618 THR 618 617 617 THR THR A . n 
A 1 619 GLY 619 618 618 GLY GLY A . n 
A 1 620 LYS 620 619 619 LYS LYS A . n 
A 1 621 PRO 621 620 620 PRO PRO A . n 
A 1 622 LEU 622 621 621 LEU LEU A . n 
A 1 623 SER 623 622 622 SER SER A . n 
A 1 624 ARG 624 623 623 ARG ARG A . n 
A 1 625 CYS 625 624 624 CYS CYS A . n 
A 1 626 GLY 626 625 625 GLY GLY A . n 
A 1 627 LYS 627 626 626 LYS LYS A . n 
A 1 628 CYS 628 627 627 CYS CYS A . n 
A 1 629 HIS 629 628 628 HIS HIS A . n 
A 1 630 ARG 630 629 629 ARG ARG A . n 
A 1 631 PHE 631 630 630 PHE PHE A . n 
A 1 632 MET 632 631 631 MET MET A . n 
A 1 633 LYS 633 632 632 LYS LYS A . n 
A 1 634 TYR 634 633 633 TYR TYR A . n 
A 1 635 ILE 635 634 634 ILE ILE A . n 
A 1 636 GLN 636 635 635 GLN GLN A . n 
A 1 637 ALA 637 636 636 ALA ALA A . n 
A 1 638 LYS 638 637 637 LYS LYS A . n 
A 1 639 PRO 639 638 638 PRO PRO A . n 
A 1 640 SER 640 639 639 SER SER A . n 
A 1 641 ARG 641 640 640 ARG ARG A . n 
A 1 642 LEU 642 641 641 LEU LEU A . n 
A 1 643 HIS 643 642 642 HIS HIS A . n 
A 1 644 CYS 644 643 643 CYS CYS A . n 
A 1 645 SER 645 644 644 SER SER A . n 
A 1 646 HIS 646 645 645 HIS HIS A . n 
A 1 647 CYS 647 646 646 CYS CYS A . n 
A 1 648 ASP 648 647 647 ASP ASP A . n 
A 1 649 GLU 649 648 648 GLU GLU A . n 
A 1 650 THR 650 649 649 THR THR A . n 
A 1 651 TYR 651 650 650 TYR TYR A . n 
A 1 652 THR 652 651 651 THR THR A . n 
A 1 653 LEU 653 652 652 LEU LEU A . n 
A 1 654 PRO 654 653 653 PRO PRO A . n 
A 1 655 ASN 655 654 654 ASN ASN A . n 
A 1 656 ASN 656 655 655 ASN ASN A . n 
A 1 657 GLY 657 656 656 GLY GLY A . n 
A 1 658 THR 658 657 657 THR THR A . n 
A 1 659 ILE 659 658 658 ILE ILE A . n 
A 1 660 LYS 660 659 659 LYS LYS A . n 
A 1 661 LEU 661 660 660 LEU LEU A . n 
A 1 662 TYR 662 661 661 TYR TYR A . n 
A 1 663 LYS 663 662 662 LYS LYS A . n 
A 1 664 GLU 664 663 663 GLU GLU A . n 
A 1 665 LEU 665 664 664 LEU LEU A . n 
A 1 666 ARG 666 665 665 ARG ARG A . n 
A 1 667 CYS 667 666 666 CYS CYS A . n 
A 1 668 PRO 668 667 667 PRO PRO A . n 
A 1 669 LEU 669 668 668 LEU LEU A . n 
A 1 670 ASP 670 669 669 ASP ASP A . n 
A 1 671 ASP 671 670 670 ASP ASP A . n 
A 1 672 PHE 672 671 671 PHE PHE A . n 
A 1 673 GLU 673 672 672 GLU GLU A . n 
A 1 674 LEU 674 673 673 LEU LEU A . n 
A 1 675 VAL 675 674 674 VAL VAL A . n 
A 1 676 LEU 676 675 675 LEU LEU A . n 
A 1 677 TRP 677 676 676 TRP TRP A . n 
A 1 678 SER 678 677 677 SER SER A . n 
A 1 679 SER 679 678 678 SER SER A . n 
A 1 680 GLY 680 679 679 GLY GLY A . n 
A 1 681 SER 681 680 680 SER SER A . n 
A 1 682 ARG 682 681 681 ARG ARG A . n 
A 1 683 GLY 683 682 682 GLY GLY A . n 
A 1 684 LYS 684 683 683 LYS LYS A . n 
A 1 685 SER 685 684 684 SER SER A . n 
A 1 686 TYR 686 685 685 TYR TYR A . n 
A 1 687 PRO 687 686 686 PRO PRO A . n 
A 1 688 LEU 688 687 687 LEU LEU A . n 
A 1 689 CYS 689 688 688 CYS CYS A . n 
A 1 690 PRO 690 689 689 PRO PRO A . n 
A 1 691 TYR 691 690 690 TYR TYR A . n 
A 1 692 CYS 692 691 691 CYS CYS A . n 
A 1 693 TYR 693 692 692 TYR TYR A . n 
A 1 694 ASN 694 693 693 ASN ASN A . n 
A 1 695 HIS 695 694 694 HIS HIS A . n 
A 1 696 PRO 696 695 695 PRO PRO A . n 
A 1 697 PRO 697 696 696 PRO PRO A . n 
A 1 698 PHE 698 697 697 PHE PHE A . n 
A 1 699 ARG 699 698 698 ARG ARG A . n 
A 1 700 ASP 700 699 699 ASP ASP A . n 
A 1 701 MET 701 700 700 MET MET A . n 
A 1 702 LYS 702 701 701 LYS LYS A . n 
A 1 703 LYS 703 702 702 LYS LYS A . n 
A 1 704 GLY 704 703 703 GLY GLY A . n 
A 1 705 MET 705 704 704 MET MET A . n 
A 1 706 GLY 706 705 705 GLY GLY A . n 
A 1 707 CYS 707 706 706 CYS CYS A . n 
A 1 708 ASN 708 707 707 ASN ASN A . n 
A 1 709 GLU 709 708 708 GLU GLU A . n 
A 1 710 CYS 710 709 709 CYS CYS A . n 
A 1 711 THR 711 710 710 THR THR A . n 
A 1 712 HIS 712 711 711 HIS HIS A . n 
A 1 713 PRO 713 712 712 PRO PRO A . n 
A 1 714 SER 714 713 713 SER SER A . n 
A 1 715 CYS 715 714 714 CYS CYS A . n 
A 1 716 GLN 716 715 715 GLN GLN A . n 
A 1 717 HIS 717 716 716 HIS HIS A . n 
A 1 718 SER 718 717 717 SER SER A . n 
B 2 1   MET 1   1   1   MET MET B . n 
B 2 2   ALA 2   2   2   ALA ALA B . n 
B 2 3   GLN 3   3   3   GLN GLN B . n 
B 2 4   VAL 4   4   4   VAL VAL B . n 
B 2 5   ALA 5   5   5   ALA ALA B . n 
B 2 6   GLY 6   6   6   GLY GLY B . n 
B 2 7   ALA 7   7   7   ALA ALA B . n 
B 2 8   ALA 8   8   8   ALA ALA B . n 
B 2 9   LEU 9   9   9   LEU LEU B . n 
B 2 10  SER 10  10  10  SER SER B . n 
B 2 11  GLN 11  11  11  GLN GLN B . n 
B 2 12  ALA 12  12  12  ALA ALA B . n 
B 2 13  GLY 13  13  13  GLY GLY B . n 
B 2 14  TRP 14  14  14  TRP TRP B . n 
B 2 15  TYR 15  15  15  TYR TYR B . n 
B 2 16  LEU 16  16  16  LEU LEU B . n 
B 2 17  SER 17  17  17  SER SER B . n 
B 2 18  ASP 18  18  18  ASP ASP B . n 
B 2 19  GLU 19  19  19  GLU GLU B . n 
B 2 20  GLY 20  20  20  GLY GLY B . n 
B 2 21  ILE 21  21  21  ILE ILE B . n 
B 2 22  GLU 22  22  22  GLU GLU B . n 
B 2 23  ALA 23  23  23  ALA ALA B . n 
B 2 24  CYS 24  24  24  CYS CYS B . n 
B 2 25  THR 25  25  25  THR THR B . n 
B 2 26  SER 26  26  26  SER SER B . n 
B 2 27  SER 27  27  27  SER SER B . n 
B 2 28  PRO 28  28  28  PRO PRO B . n 
B 2 29  ASP 29  29  29  ASP ASP B . n 
B 2 30  LYS 30  30  30  LYS LYS B . n 
B 2 31  VAL 31  31  31  VAL VAL B . n 
B 2 32  ASN 32  32  32  ASN ASN B . n 
B 2 33  VAL 33  33  33  VAL VAL B . n 
B 2 34  ASN 34  34  34  ASN ASN B . n 
B 2 35  ASP 35  35  35  ASP ASP B . n 
B 2 36  ILE 36  36  36  ILE ILE B . n 
B 2 37  ILE 37  37  37  ILE ILE B . n 
B 2 38  LEU 38  38  38  LEU LEU B . n 
B 2 39  ILE 39  39  39  ILE ILE B . n 
B 2 40  ALA 40  40  40  ALA ALA B . n 
B 2 41  LEU 41  41  41  LEU LEU B . n 
B 2 42  ASN 42  42  42  ASN ASN B . n 
B 2 43  THR 43  43  43  THR THR B . n 
B 2 44  ASP 44  44  44  ASP ASP B . n 
B 2 45  LEU 45  45  45  LEU LEU B . n 
B 2 46  ARG 46  46  46  ARG ARG B . n 
B 2 47  THR 47  47  47  THR THR B . n 
B 2 48  ILE 48  48  48  ILE ILE B . n 
B 2 49  GLY 49  49  49  GLY GLY B . n 
B 2 50  LYS 50  50  50  LYS LYS B . n 
B 2 51  LYS 51  51  51  LYS LYS B . n 
B 2 52  PHE 52  52  52  PHE PHE B . n 
B 2 53  LEU 53  53  53  LEU LEU B . n 
B 2 54  PRO 54  54  54  PRO PRO B . n 
B 2 55  SER 55  55  55  SER SER B . n 
B 2 56  ASP 56  56  56  ASP ASP B . n 
B 2 57  ILE 57  57  57  ILE ILE B . n 
B 2 58  ASN 58  58  58  ASN ASN B . n 
B 2 59  SER 59  59  59  SER SER B . n 
B 2 60  GLY 60  60  60  GLY GLY B . n 
B 2 61  LYS 61  61  61  LYS LYS B . n 
B 2 62  VAL 62  62  62  VAL VAL B . n 
B 2 63  GLU 63  63  63  GLU GLU B . n 
B 2 64  LYS 64  64  64  LYS LYS B . n 
B 2 65  LEU 65  65  65  LEU LEU B . n 
B 2 66  GLU 66  66  66  GLU GLU B . n 
B 2 67  GLY 67  67  67  GLY GLY B . n 
B 2 68  PRO 68  68  68  PRO PRO B . n 
B 2 69  CYS 69  69  69  CYS CYS B . n 
B 2 70  VAL 70  70  70  VAL VAL B . n 
B 2 71  LEU 71  71  71  LEU LEU B . n 
B 2 72  GLN 72  72  72  GLN GLN B . n 
B 2 73  ILE 73  73  73  ILE ILE B . n 
B 2 74  GLN 74  74  74  GLN GLN B . n 
B 2 75  LYS 75  75  75  LYS LYS B . n 
B 2 76  ILE 76  76  76  ILE ILE B . n 
B 2 77  ARG 77  77  77  ARG ARG B . n 
B 2 78  ASN 78  78  78  ASN ASN B . n 
B 2 79  VAL 79  79  79  VAL VAL B . n 
B 2 80  ALA 80  80  80  ALA ALA B . n 
B 2 81  ALA 81  81  81  ALA ALA B . n 
B 2 82  PRO 82  82  82  PRO PRO B . n 
B 2 83  LYS 83  83  83  LYS LYS B . n 
B 2 84  ASP 84  84  84  ASP ASP B . n 
B 2 85  ASN 85  85  85  ASN ASN B . n 
B 2 86  GLU 86  86  86  GLU GLU B . n 
B 2 87  GLU 87  87  87  GLU GLU B . n 
B 2 88  SER 88  88  88  SER SER B . n 
B 2 89  GLN 89  89  89  GLN GLN B . n 
B 2 90  ALA 90  90  90  ALA ALA B . n 
B 2 91  ALA 91  91  91  ALA ALA B . n 
B 2 92  PRO 92  92  92  PRO PRO B . n 
B 2 93  ARG 93  93  93  ARG ARG B . n 
B 2 94  MET 94  94  94  MET MET B . n 
B 2 95  LEU 95  95  95  LEU LEU B . n 
B 2 96  ARG 96  96  96  ARG ARG B . n 
B 2 97  LEU 97  97  97  LEU LEU B . n 
B 2 98  GLN 98  98  98  GLN GLN B . n 
B 2 99  MET 99  99  99  MET MET B . n 
B 2 100 THR 100 100 100 THR THR B . n 
B 2 101 ASP 101 101 101 ASP ASP B . n 
B 2 102 GLY 102 102 102 GLY GLY B . n 
B 2 103 HIS 103 103 103 HIS HIS B . n 
B 2 104 ILE 104 104 104 ILE ILE B . n 
B 2 105 SER 105 105 105 SER SER B . n 
B 2 106 CYS 106 106 106 CYS CYS B . n 
B 2 107 THR 107 107 107 THR THR B . n 
B 2 108 ALA 108 108 108 ALA ALA B . n 
B 2 109 VAL 109 109 109 VAL VAL B . n 
B 2 110 GLU 110 110 110 GLU GLU B . n 
B 2 111 PHE 111 111 111 PHE PHE B . n 
B 2 112 SER 112 112 112 SER SER B . n 
B 2 113 TYR 113 113 113 TYR TYR B . n 
B 2 114 MET 114 114 114 MET MET B . n 
B 2 115 SER 115 115 115 SER SER B . n 
B 2 116 LYS 116 116 116 LYS LYS B . n 
B 2 117 ILE 117 117 117 ILE ILE B . n 
B 2 118 SER 118 118 118 SER SER B . n 
B 2 119 LEU 119 119 119 LEU LEU B . n 
B 2 120 ASN 120 120 120 ASN ASN B . n 
B 2 121 THR 121 121 121 THR THR B . n 
B 2 122 PRO 122 122 122 PRO PRO B . n 
B 2 123 PRO 123 123 123 PRO PRO B . n 
B 2 124 GLY 124 124 124 GLY GLY B . n 
B 2 125 THR 125 125 125 THR THR B . n 
B 2 126 LYS 126 126 126 LYS LYS B . n 
B 2 127 VAL 127 127 127 VAL VAL B . n 
B 2 128 LYS 128 128 128 LYS LYS B . n 
B 2 129 LEU 129 129 129 LEU LEU B . n 
B 2 130 SER 130 130 130 SER SER B . n 
B 2 131 GLY 131 131 131 GLY GLY B . n 
B 2 132 ILE 132 132 132 ILE ILE B . n 
B 2 133 VAL 133 133 133 VAL VAL B . n 
B 2 134 ASP 134 134 134 ASP ASP B . n 
B 2 135 ILE 135 135 135 ILE ILE B . n 
B 2 136 LYS 136 136 136 LYS LYS B . n 
B 2 137 ASN 137 137 137 ASN ASN B . n 
B 2 138 GLY 138 138 138 GLY GLY B . n 
B 2 139 PHE 139 139 139 PHE PHE B . n 
B 2 140 LEU 140 140 140 LEU LEU B . n 
B 2 141 LEU 141 141 141 LEU LEU B . n 
B 2 142 LEU 142 142 142 LEU LEU B . n 
B 2 143 ASN 143 143 143 ASN ASN B . n 
B 2 144 ASP 144 144 144 ASP ASP B . n 
B 2 145 SER 145 145 145 SER SER B . n 
B 2 146 ASN 146 146 146 ASN ASN B . n 
B 2 147 THR 147 147 147 THR THR B . n 
B 2 148 THR 148 148 148 THR THR B . n 
B 2 149 VAL 149 149 149 VAL VAL B . n 
B 2 150 LEU 150 150 150 LEU LEU B . n 
B 2 151 GLY 151 151 151 GLY GLY B . n 
B 2 152 GLY 152 152 152 GLY GLY B . n 
B 2 153 GLU 153 153 153 GLU GLU B . n 
B 2 154 VAL 154 154 154 VAL VAL B . n 
B 2 155 GLU 155 155 155 GLU GLU B . n 
B 2 156 HIS 156 156 156 HIS HIS B . n 
B 2 157 LEU 157 157 157 LEU LEU B . n 
B 2 158 ILE 158 158 158 ILE ILE B . n 
B 2 159 GLU 159 159 159 GLU GLU B . n 
B 2 160 LYS 160 160 160 LYS LYS B . n 
B 2 161 TRP 161 161 161 TRP TRP B . n 
B 2 162 GLU 162 162 162 GLU GLU B . n 
B 2 163 LEU 163 163 163 LEU LEU B . n 
B 2 164 GLN 164 164 164 GLN GLN B . n 
B 2 165 ARG 165 165 165 ARG ARG B . n 
B 2 166 SER 166 166 166 SER SER B . n 
B 2 167 LEU 167 167 167 LEU LEU B . n 
B 2 168 SER 168 168 168 SER SER B . n 
B 2 169 LYS 169 169 169 LYS LYS B . n 
B 2 170 HIS 170 170 170 HIS HIS B . n 
B 2 171 ASN 171 171 171 ASN ASN B . n 
B 2 172 ARG 172 172 172 ARG ARG B . n 
B 2 173 SER 173 173 173 SER SER B . n 
B 2 174 ASN 174 174 174 ASN ASN B . n 
B 2 175 ILE 175 175 175 ILE ILE B . n 
B 2 176 GLY 176 176 176 GLY GLY B . n 
B 2 177 THR 177 177 177 THR THR B . n 
B 2 178 GLU 178 178 178 GLU GLU B . n 
B 2 179 GLY 179 179 179 GLY GLY B . n 
B 2 180 GLY 180 180 180 GLY GLY B . n 
B 2 181 PRO 181 181 181 PRO PRO B . n 
B 2 182 PRO 182 182 182 PRO PRO B . n 
B 2 183 PRO 183 183 183 PRO PRO B . n 
B 2 184 PHE 184 184 184 PHE PHE B . n 
B 2 185 VAL 185 185 185 VAL VAL B . n 
B 2 186 PRO 186 186 186 PRO PRO B . n 
B 2 187 PHE 187 187 187 PHE PHE B . n 
B 2 188 GLY 188 188 188 GLY GLY B . n 
B 2 189 GLN 189 189 189 GLN GLN B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 ZN ? ? ZN ? ? 'SUBJECT OF INVESTIGATION' ? 
2 MN ? ? MN ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 3 MN 1 801 1 MN MN A . 
D 4 ZN 1 802 1 ZN ZN A . 
E 4 ZN 1 803 2 ZN ZN A . 
F 4 ZN 1 804 3 ZN ZN A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 B GLN 72 ? CG  ? B GLN 72 CG  
2 1 Y 1 B GLN 72 ? CD  ? B GLN 72 CD  
3 1 Y 1 B GLN 72 ? OE1 ? B GLN 72 OE1 
4 1 Y 1 B GLN 72 ? NE2 ? B GLN 72 NE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CAH 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CAH 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CAH 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9CAH 
_struct.title                        'Human TOP3B-TDRD3 complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CAH 
_struct_keywords.text            'Topoisomerase, ISOMERASE' 
_struct_keywords.pdbx_keywords   ISOMERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP TOP3B_HUMAN O95985 ?        1 
;MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGHVMTLDFLGKYNKWDKVDPAE
LFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDI
CNAMACLGEPDHNEALSVDARQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLALNTVEMLRVASSSLGMGPQH
AMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEAE
LGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEVMPWQSVPLEESLPTCQRGDAFPVGE
VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYYKIDAELVLPTI
RSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSIAGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSR
LHCSHCDETYTLPQNGTIKLYKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHS
;
1 
2 UNP TDRD3_HUMAN Q9H7E2 Q9H7E2-3 2 
;MAQVAGAALSQAGWYLSDEGIEACTSSPDKVNVNDIILIALNTDLRTIGKKFLPSDINSGKVEKLEGPCVLQIQKIRNVA
APKDNEESQAAPRMLRLQMTDGHISCTAVEFSYMSKISLNTPPGTKVKLSGIVDIKNGFLLLNDSNTTVLGGEVEHLIEK
WELQRSLSKHNRSNIGTEGGPPPFVPFGQ
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9CAH A 2 ? 718 ? O95985 1 ? 717 ? 1 717 
2 2 9CAH B 1 ? 189 ? Q9H7E2 1 ? 189 ? 1 189 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9CAH HIS A 1   ? UNP O95985 ?   ?   'expression tag' 0   1 
1 9CAH ASN A 655 ? UNP O95985 GLN 654 conflict         654 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 11  ? ARG A 24  ? LYS A 10  ARG A 23  1 ? 14 
HELX_P HELX_P2  AA2 ASN A 94  ? LEU A 97  ? ASN A 93  LEU A 96  5 ? 4  
HELX_P HELX_P3  AA3 ASN A 98  ? GLY A 107 ? ASN A 97  GLY A 106 1 ? 10 
HELX_P HELX_P4  AA4 ASP A 120 ? LEU A 135 ? ASP A 119 LEU A 134 1 ? 16 
HELX_P HELX_P5  AA5 PRO A 136 ? MET A 138 ? PRO A 135 MET A 137 5 ? 3  
HELX_P HELX_P6  AA6 THR A 159 ? CYS A 167 ? THR A 158 CYS A 166 1 ? 9  
HELX_P HELX_P7  AA7 ASP A 172 ? PHE A 201 ? ASP A 171 PHE A 200 1 ? 30 
HELX_P HELX_P8  AA8 ASP A 209 ? ILE A 213 ? ASP A 208 ILE A 212 5 ? 5  
HELX_P HELX_P9  AA9 CYS A 218 ? SER A 235 ? CYS A 217 SER A 234 1 ? 18 
HELX_P HELX_P10 AB1 ASP A 267 ? MET A 277 ? ASP A 266 MET A 276 1 ? 11 
HELX_P HELX_P11 AB2 ASN A 303 ? SER A 314 ? ASN A 302 SER A 313 1 ? 12 
HELX_P HELX_P12 AB3 GLY A 318 ? GLY A 333 ? GLY A 317 GLY A 332 1 ? 16 
HELX_P HELX_P13 AB4 ASP A 350 ? GLN A 358 ? ASP A 349 GLN A 357 1 ? 9  
HELX_P HELX_P14 AB5 ALA A 365 ? GLU A 374 ? ALA A 364 GLU A 373 1 ? 10 
HELX_P HELX_P15 AB6 GLY A 404 ? VAL A 421 ? GLY A 403 VAL A 420 1 ? 18 
HELX_P HELX_P16 AB7 MET A 457 ? SER A 461 ? MET A 456 SER A 460 5 ? 5  
HELX_P HELX_P17 AB8 THR A 496 ? GLY A 508 ? THR A 495 GLY A 507 1 ? 13 
HELX_P HELX_P18 AB9 SER A 514 ? ARG A 525 ? SER A 513 ARG A 524 1 ? 12 
HELX_P HELX_P19 AC1 THR A 539 ? ASP A 553 ? THR A 538 ASP A 552 1 ? 15 
HELX_P HELX_P20 AC2 ALA A 554 ? VAL A 557 ? ALA A 553 VAL A 556 5 ? 4  
HELX_P HELX_P21 AC3 THR A 560 ? GLN A 574 ? THR A 559 GLN A 573 1 ? 15 
HELX_P HELX_P22 AC4 ASP A 578 ? SER A 600 ? ASP A 577 SER A 599 1 ? 23 
HELX_P HELX_P23 AC5 ILE A 601 ? SER A 613 ? ILE A 600 SER A 612 1 ? 13 
HELX_P HELX_P24 AC6 CYS A 689 ? HIS A 695 ? CYS A 688 HIS A 694 1 ? 7  
HELX_P HELX_P25 AC7 GLY A 706 ? CYS A 710 ? GLY A 705 CYS A 709 5 ? 5  
HELX_P HELX_P26 AC8 ALA B 2   ? GLY B 13  ? ALA B 2   GLY B 13  1 ? 12 
HELX_P HELX_P27 AC9 SER B 17  ? CYS B 24  ? SER B 17  CYS B 24  1 ? 8  
HELX_P HELX_P28 AD1 ASN B 32  ? THR B 43  ? ASN B 32  THR B 43  1 ? 12 
HELX_P HELX_P29 AD2 VAL B 154 ? GLU B 162 ? VAL B 154 GLU B 162 1 ? 9  
HELX_P HELX_P30 AD3 GLU B 162 ? SER B 168 ? GLU B 162 SER B 168 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A GLU 10  OE2 ? ? ? 1_555 C MN . MN ? ? A GLU 9   A MN 801 1_555 ? ? ? ? ? ? ? 2.049 ? ? 
metalc2  metalc ? ? A ASP 118 OD2 ? ? ? 1_555 C MN . MN ? ? A ASP 117 A MN 801 1_555 ? ? ? ? ? ? ? 2.141 ? ? 
metalc3  metalc ? ? A CYS 625 SG  ? ? ? 1_555 E ZN . ZN ? ? A CYS 624 A ZN 803 1_555 ? ? ? ? ? ? ? 2.337 ? ? 
metalc4  metalc ? ? A CYS 628 SG  ? ? ? 1_555 E ZN . ZN ? ? A CYS 627 A ZN 803 1_555 ? ? ? ? ? ? ? 2.332 ? ? 
metalc5  metalc ? ? A CYS 644 SG  ? ? ? 1_555 E ZN . ZN ? ? A CYS 643 A ZN 803 1_555 ? ? ? ? ? ? ? 2.331 ? ? 
metalc6  metalc ? ? A CYS 647 SG  ? ? ? 1_555 E ZN . ZN ? ? A CYS 646 A ZN 803 1_555 ? ? ? ? ? ? ? 2.329 ? ? 
metalc7  metalc ? ? A CYS 667 SG  ? ? ? 1_555 F ZN . ZN ? ? A CYS 666 A ZN 804 1_555 ? ? ? ? ? ? ? 2.316 ? ? 
metalc8  metalc ? ? A ASP 670 OD1 ? ? ? 1_555 F ZN . ZN ? ? A ASP 669 A ZN 804 1_555 ? ? ? ? ? ? ? 2.663 ? ? 
metalc9  metalc ? ? A ASP 670 OD2 ? ? ? 1_555 F ZN . ZN ? ? A ASP 669 A ZN 804 1_555 ? ? ? ? ? ? ? 2.091 ? ? 
metalc10 metalc ? ? A CYS 689 SG  ? ? ? 1_555 F ZN . ZN ? ? A CYS 688 A ZN 804 1_555 ? ? ? ? ? ? ? 2.315 ? ? 
metalc11 metalc ? ? A CYS 692 SG  ? ? ? 1_555 F ZN . ZN ? ? A CYS 691 A ZN 804 1_555 ? ? ? ? ? ? ? 2.340 ? ? 
metalc12 metalc ? ? A CYS 707 SG  ? ? ? 1_555 D ZN . ZN ? ? A CYS 706 A ZN 802 1_555 ? ? ? ? ? ? ? 2.431 ? ? 
metalc13 metalc ? ? A CYS 710 SG  ? ? ? 1_555 D ZN . ZN ? ? A CYS 709 A ZN 802 1_555 ? ? ? ? ? ? ? 2.484 ? ? 
metalc14 metalc ? ? A CYS 715 SG  ? ? ? 1_555 D ZN . ZN ? ? A CYS 714 A ZN 802 1_555 ? ? ? ? ? ? ? 2.448 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OE2 ? A GLU 10  ? A GLU 9   ? 1_555 MN ? C MN . ? A MN 801 ? 1_555 OD2 ? A ASP 118 ? A ASP 117 ? 1_555 92.8  ? 
2  SG  ? A CYS 625 ? A CYS 624 ? 1_555 ZN ? E ZN . ? A ZN 803 ? 1_555 SG  ? A CYS 628 ? A CYS 627 ? 1_555 111.7 ? 
3  SG  ? A CYS 625 ? A CYS 624 ? 1_555 ZN ? E ZN . ? A ZN 803 ? 1_555 SG  ? A CYS 644 ? A CYS 643 ? 1_555 108.3 ? 
4  SG  ? A CYS 628 ? A CYS 627 ? 1_555 ZN ? E ZN . ? A ZN 803 ? 1_555 SG  ? A CYS 644 ? A CYS 643 ? 1_555 112.9 ? 
5  SG  ? A CYS 625 ? A CYS 624 ? 1_555 ZN ? E ZN . ? A ZN 803 ? 1_555 SG  ? A CYS 647 ? A CYS 646 ? 1_555 113.4 ? 
6  SG  ? A CYS 628 ? A CYS 627 ? 1_555 ZN ? E ZN . ? A ZN 803 ? 1_555 SG  ? A CYS 647 ? A CYS 646 ? 1_555 104.5 ? 
7  SG  ? A CYS 644 ? A CYS 643 ? 1_555 ZN ? E ZN . ? A ZN 803 ? 1_555 SG  ? A CYS 647 ? A CYS 646 ? 1_555 106.0 ? 
8  SG  ? A CYS 667 ? A CYS 666 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 OD1 ? A ASP 670 ? A ASP 669 ? 1_555 84.2  ? 
9  SG  ? A CYS 667 ? A CYS 666 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 OD2 ? A ASP 670 ? A ASP 669 ? 1_555 137.6 ? 
10 OD1 ? A ASP 670 ? A ASP 669 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 OD2 ? A ASP 670 ? A ASP 669 ? 1_555 53.5  ? 
11 SG  ? A CYS 667 ? A CYS 666 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 SG  ? A CYS 689 ? A CYS 688 ? 1_555 117.0 ? 
12 OD1 ? A ASP 670 ? A ASP 669 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 SG  ? A CYS 689 ? A CYS 688 ? 1_555 94.2  ? 
13 OD2 ? A ASP 670 ? A ASP 669 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 SG  ? A CYS 689 ? A CYS 688 ? 1_555 71.1  ? 
14 SG  ? A CYS 667 ? A CYS 666 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 SG  ? A CYS 692 ? A CYS 691 ? 1_555 121.1 ? 
15 OD1 ? A ASP 670 ? A ASP 669 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 SG  ? A CYS 692 ? A CYS 691 ? 1_555 154.3 ? 
16 OD2 ? A ASP 670 ? A ASP 669 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 SG  ? A CYS 692 ? A CYS 691 ? 1_555 101.2 ? 
17 SG  ? A CYS 689 ? A CYS 688 ? 1_555 ZN ? F ZN . ? A ZN 804 ? 1_555 SG  ? A CYS 692 ? A CYS 691 ? 1_555 78.9  ? 
18 SG  ? A CYS 707 ? A CYS 706 ? 1_555 ZN ? D ZN . ? A ZN 802 ? 1_555 SG  ? A CYS 710 ? A CYS 709 ? 1_555 103.3 ? 
19 SG  ? A CYS 707 ? A CYS 706 ? 1_555 ZN ? D ZN . ? A ZN 802 ? 1_555 SG  ? A CYS 715 ? A CYS 714 ? 1_555 107.4 ? 
20 SG  ? A CYS 710 ? A CYS 709 ? 1_555 ZN ? D ZN . ? A ZN 802 ? 1_555 SG  ? A CYS 715 ? A CYS 714 ? 1_555 135.7 ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 2 ? 
AA3 ? 7 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 3 ? 
AA8 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA3 6 7 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 28  ? LYS A 31  ? SER A 27  LYS A 30  
AA1 2 SER A 38  ? PHE A 46  ? SER A 37  PHE A 45  
AA1 3 GLN A 49  ? SER A 57  ? GLN A 48  SER A 56  
AA1 4 THR A 4   ? ALA A 9   ? THR A 3   ALA A 8   
AA1 5 TYR A 112 ? TRP A 116 ? TYR A 111 TRP A 115 
AA1 6 VAL A 148 ? ARG A 150 ? VAL A 147 ARG A 149 
AA2 1 LEU A 65  ? PHE A 67  ? LEU A 64  PHE A 66  
AA2 2 THR A 88  ? LYS A 90  ? THR A 87  LYS A 89  
AA3 1 LEU A 244 ? ASN A 249 ? LEU A 243 ASN A 248 
AA3 2 SER A 255 ? TRP A 260 ? SER A 254 TRP A 259 
AA3 3 GLU A 439 ? SER A 450 ? GLU A 438 SER A 449 
AA3 4 CYS A 425 ? ILE A 436 ? CYS A 424 ILE A 435 
AA3 5 GLU A 283 ? LYS A 296 ? GLU A 282 LYS A 295 
AA3 6 ALA A 476 ? MET A 484 ? ALA A 475 MET A 483 
AA3 7 LEU A 244 ? ASN A 249 ? LEU A 243 ASN A 248 
AA4 1 VAL A 528 ? GLU A 531 ? VAL A 527 GLU A 530 
AA4 2 ARG A 535 ? PRO A 538 ? ARG A 534 PRO A 537 
AA5 1 LYS A 620 ? ARG A 624 ? LYS A 619 ARG A 623 
AA5 2 PHE A 631 ? TYR A 634 ? PHE A 630 TYR A 633 
AA6 1 HIS A 643 ? CYS A 644 ? HIS A 642 CYS A 643 
AA6 2 GLU A 649 ? THR A 650 ? GLU A 648 THR A 649 
AA7 1 THR A 658 ? LEU A 661 ? THR A 657 LEU A 660 
AA7 2 VAL A 675 ? SER A 678 ? VAL A 674 SER A 677 
AA7 3 SER A 685 ? LEU A 688 ? SER A 684 LEU A 687 
AA8 1 LEU B 140 ? LEU B 142 ? LEU B 140 LEU B 142 
AA8 2 SER B 105 ? GLU B 110 ? SER B 105 GLU B 110 
AA8 3 LEU B 95  ? THR B 100 ? LEU B 95  THR B 100 
AA8 4 CYS B 69  ? ASN B 78  ? CYS B 69  ASN B 78  
AA8 5 LYS B 126 ? LEU B 129 ? LYS B 126 LEU B 129 
AA8 6 THR B 147 ? VAL B 149 ? THR B 147 VAL B 149 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N HIS A 30  ? N HIS A 29  O VAL A 39  ? O VAL A 38  
AA1 2 3 N PHE A 46  ? N PHE A 45  O GLN A 49  ? O GLN A 48  
AA1 3 4 O THR A 56  ? O THR A 55  N MET A 7   ? N MET A 6   
AA1 4 5 N VAL A 8   ? N VAL A 7   O TRP A 116 ? O TRP A 115 
AA1 5 6 N ILE A 113 ? N ILE A 112 O PHE A 149 ? O PHE A 148 
AA2 1 2 N ASP A 66  ? N ASP A 65  O GLU A 89  ? O GLU A 88  
AA3 1 2 N ALA A 246 ? N ALA A 245 O LEU A 258 ? O LEU A 257 
AA3 2 3 N ASP A 259 ? N ASP A 258 O THR A 442 ? O THR A 441 
AA3 3 4 O THR A 447 ? O THR A 446 N LEU A 428 ? N LEU A 427 
AA3 4 5 O CYS A 425 ? O CYS A 424 N LYS A 296 ? N LYS A 295 
AA3 5 6 N ALA A 284 ? N ALA A 283 O PHE A 477 ? O PHE A 476 
AA3 6 7 O PRO A 478 ? O PRO A 477 N ASN A 249 ? N ASN A 248 
AA4 1 2 N THR A 529 ? N THR A 528 O LYS A 537 ? O LYS A 536 
AA5 1 2 N LYS A 620 ? N LYS A 619 O TYR A 634 ? O TYR A 633 
AA6 1 2 N CYS A 644 ? N CYS A 643 O GLU A 649 ? O GLU A 648 
AA7 1 2 N LYS A 660 ? N LYS A 659 O LEU A 676 ? O LEU A 675 
AA7 2 3 N VAL A 675 ? N VAL A 674 O LEU A 688 ? O LEU A 687 
AA8 1 2 O LEU B 142 ? O LEU B 142 N VAL B 109 ? N VAL B 109 
AA8 2 3 O ALA B 108 ? O ALA B 108 N LEU B 97  ? N LEU B 97  
AA8 3 4 O GLN B 98  ? O GLN B 98  N GLN B 74  ? N GLN B 74  
AA8 4 5 N CYS B 69  ? N CYS B 69  O LEU B 129 ? O LEU B 129 
AA8 5 6 N LYS B 128 ? N LYS B 128 O THR B 148 ? O THR B 148 
# 
_pdbx_entry_details.entry_id                   9CAH 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ALA A 46  ? ? 52.80   -97.27  
2  1 PRO A 78  ? ? -76.42  42.89   
3  1 LYS A 90  ? ? -83.81  -74.78  
4  1 GLU A 91  ? ? -146.64 -27.17  
5  1 ALA A 92  ? ? 57.69   74.39   
6  1 ASN A 93  ? ? 68.70   71.35   
7  1 TRP A 115 ? ? -98.20  33.24   
8  1 ALA A 140 ? ? 66.17   171.06  
9  1 THR A 158 ? ? 71.42   -16.02  
10 1 LYS A 251 ? ? -138.61 -30.60  
11 1 ASP A 252 ? ? -132.05 -31.58  
12 1 VAL A 262 ? ? 65.41   -69.78  
13 1 PRO A 337 ? ? -88.59  46.98   
14 1 ASP A 386 ? ? -78.61  -165.91 
15 1 SER A 421 ? ? -162.79 -166.94 
16 1 THR A 453 ? ? -78.32  48.17   
17 1 MET A 456 ? ? -113.15 77.21   
18 1 GLN A 573 ? ? -91.57  47.87   
19 1 ALA A 576 ? ? 179.76  161.45  
20 1 SER A 622 ? ? -48.79  151.30  
21 1 ASN A 655 ? ? 61.74   61.02   
22 1 TYR A 661 ? ? -105.11 65.31   
23 1 GLU A 663 ? ? 61.47   -17.19  
24 1 LEU A 664 ? ? -44.68  164.36  
25 1 ASP A 670 ? ? 75.93   -1.88   
26 1 CYS A 714 ? ? 61.62   67.38   
27 1 SER B 26  ? ? -125.76 -165.88 
28 1 SER B 55  ? ? -82.96  48.55   
29 1 GLU B 63  ? ? -140.85 27.07   
30 1 GLN B 89  ? ? -92.38  51.71   
31 1 LEU B 150 ? ? -97.03  57.92   
32 1 GLU B 162 ? ? -59.54  -8.60   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9CAH 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9CAH 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.16 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               469366 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            6.8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'human TOP3B-TDRD3 Complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        9CAH 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9CAH 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9CAH 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
ILE N    N  N N 158 
ILE CA   C  N S 159 
ILE C    C  N N 160 
ILE O    O  N N 161 
ILE CB   C  N S 162 
ILE CG1  C  N N 163 
ILE CG2  C  N N 164 
ILE CD1  C  N N 165 
ILE OXT  O  N N 166 
ILE H    H  N N 167 
ILE H2   H  N N 168 
ILE HA   H  N N 169 
ILE HB   H  N N 170 
ILE HG12 H  N N 171 
ILE HG13 H  N N 172 
ILE HG21 H  N N 173 
ILE HG22 H  N N 174 
ILE HG23 H  N N 175 
ILE HD11 H  N N 176 
ILE HD12 H  N N 177 
ILE HD13 H  N N 178 
ILE HXT  H  N N 179 
LEU N    N  N N 180 
LEU CA   C  N S 181 
LEU C    C  N N 182 
LEU O    O  N N 183 
LEU CB   C  N N 184 
LEU CG   C  N N 185 
LEU CD1  C  N N 186 
LEU CD2  C  N N 187 
LEU OXT  O  N N 188 
LEU H    H  N N 189 
LEU H2   H  N N 190 
LEU HA   H  N N 191 
LEU HB2  H  N N 192 
LEU HB3  H  N N 193 
LEU HG   H  N N 194 
LEU HD11 H  N N 195 
LEU HD12 H  N N 196 
LEU HD13 H  N N 197 
LEU HD21 H  N N 198 
LEU HD22 H  N N 199 
LEU HD23 H  N N 200 
LEU HXT  H  N N 201 
LYS N    N  N N 202 
LYS CA   C  N S 203 
LYS C    C  N N 204 
LYS O    O  N N 205 
LYS CB   C  N N 206 
LYS CG   C  N N 207 
LYS CD   C  N N 208 
LYS CE   C  N N 209 
LYS NZ   N  N N 210 
LYS OXT  O  N N 211 
LYS H    H  N N 212 
LYS H2   H  N N 213 
LYS HA   H  N N 214 
LYS HB2  H  N N 215 
LYS HB3  H  N N 216 
LYS HG2  H  N N 217 
LYS HG3  H  N N 218 
LYS HD2  H  N N 219 
LYS HD3  H  N N 220 
LYS HE2  H  N N 221 
LYS HE3  H  N N 222 
LYS HZ1  H  N N 223 
LYS HZ2  H  N N 224 
LYS HZ3  H  N N 225 
LYS HXT  H  N N 226 
MET N    N  N N 227 
MET CA   C  N S 228 
MET C    C  N N 229 
MET O    O  N N 230 
MET CB   C  N N 231 
MET CG   C  N N 232 
MET SD   S  N N 233 
MET CE   C  N N 234 
MET OXT  O  N N 235 
MET H    H  N N 236 
MET H2   H  N N 237 
MET HA   H  N N 238 
MET HB2  H  N N 239 
MET HB3  H  N N 240 
MET HG2  H  N N 241 
MET HG3  H  N N 242 
MET HE1  H  N N 243 
MET HE2  H  N N 244 
MET HE3  H  N N 245 
MET HXT  H  N N 246 
MN  MN   MN N N 247 
PHE N    N  N N 248 
PHE CA   C  N S 249 
PHE C    C  N N 250 
PHE O    O  N N 251 
PHE CB   C  N N 252 
PHE CG   C  Y N 253 
PHE CD1  C  Y N 254 
PHE CD2  C  Y N 255 
PHE CE1  C  Y N 256 
PHE CE2  C  Y N 257 
PHE CZ   C  Y N 258 
PHE OXT  O  N N 259 
PHE H    H  N N 260 
PHE H2   H  N N 261 
PHE HA   H  N N 262 
PHE HB2  H  N N 263 
PHE HB3  H  N N 264 
PHE HD1  H  N N 265 
PHE HD2  H  N N 266 
PHE HE1  H  N N 267 
PHE HE2  H  N N 268 
PHE HZ   H  N N 269 
PHE HXT  H  N N 270 
PRO N    N  N N 271 
PRO CA   C  N S 272 
PRO C    C  N N 273 
PRO O    O  N N 274 
PRO CB   C  N N 275 
PRO CG   C  N N 276 
PRO CD   C  N N 277 
PRO OXT  O  N N 278 
PRO H    H  N N 279 
PRO HA   H  N N 280 
PRO HB2  H  N N 281 
PRO HB3  H  N N 282 
PRO HG2  H  N N 283 
PRO HG3  H  N N 284 
PRO HD2  H  N N 285 
PRO HD3  H  N N 286 
PRO HXT  H  N N 287 
SER N    N  N N 288 
SER CA   C  N S 289 
SER C    C  N N 290 
SER O    O  N N 291 
SER CB   C  N N 292 
SER OG   O  N N 293 
SER OXT  O  N N 294 
SER H    H  N N 295 
SER H2   H  N N 296 
SER HA   H  N N 297 
SER HB2  H  N N 298 
SER HB3  H  N N 299 
SER HG   H  N N 300 
SER HXT  H  N N 301 
THR N    N  N N 302 
THR CA   C  N S 303 
THR C    C  N N 304 
THR O    O  N N 305 
THR CB   C  N R 306 
THR OG1  O  N N 307 
THR CG2  C  N N 308 
THR OXT  O  N N 309 
THR H    H  N N 310 
THR H2   H  N N 311 
THR HA   H  N N 312 
THR HB   H  N N 313 
THR HG1  H  N N 314 
THR HG21 H  N N 315 
THR HG22 H  N N 316 
THR HG23 H  N N 317 
THR HXT  H  N N 318 
TRP N    N  N N 319 
TRP CA   C  N S 320 
TRP C    C  N N 321 
TRP O    O  N N 322 
TRP CB   C  N N 323 
TRP CG   C  Y N 324 
TRP CD1  C  Y N 325 
TRP CD2  C  Y N 326 
TRP NE1  N  Y N 327 
TRP CE2  C  Y N 328 
TRP CE3  C  Y N 329 
TRP CZ2  C  Y N 330 
TRP CZ3  C  Y N 331 
TRP CH2  C  Y N 332 
TRP OXT  O  N N 333 
TRP H    H  N N 334 
TRP H2   H  N N 335 
TRP HA   H  N N 336 
TRP HB2  H  N N 337 
TRP HB3  H  N N 338 
TRP HD1  H  N N 339 
TRP HE1  H  N N 340 
TRP HE3  H  N N 341 
TRP HZ2  H  N N 342 
TRP HZ3  H  N N 343 
TRP HH2  H  N N 344 
TRP HXT  H  N N 345 
TYR N    N  N N 346 
TYR CA   C  N S 347 
TYR C    C  N N 348 
TYR O    O  N N 349 
TYR CB   C  N N 350 
TYR CG   C  Y N 351 
TYR CD1  C  Y N 352 
TYR CD2  C  Y N 353 
TYR CE1  C  Y N 354 
TYR CE2  C  Y N 355 
TYR CZ   C  Y N 356 
TYR OH   O  N N 357 
TYR OXT  O  N N 358 
TYR H    H  N N 359 
TYR H2   H  N N 360 
TYR HA   H  N N 361 
TYR HB2  H  N N 362 
TYR HB3  H  N N 363 
TYR HD1  H  N N 364 
TYR HD2  H  N N 365 
TYR HE1  H  N N 366 
TYR HE2  H  N N 367 
TYR HH   H  N N 368 
TYR HXT  H  N N 369 
VAL N    N  N N 370 
VAL CA   C  N S 371 
VAL C    C  N N 372 
VAL O    O  N N 373 
VAL CB   C  N N 374 
VAL CG1  C  N N 375 
VAL CG2  C  N N 376 
VAL OXT  O  N N 377 
VAL H    H  N N 378 
VAL H2   H  N N 379 
VAL HA   H  N N 380 
VAL HB   H  N N 381 
VAL HG11 H  N N 382 
VAL HG12 H  N N 383 
VAL HG13 H  N N 384 
VAL HG21 H  N N 385 
VAL HG22 H  N N 386 
VAL HG23 H  N N 387 
VAL HXT  H  N N 388 
ZN  ZN   ZN N N 389 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-06-17 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9CAH 
_em_admin.last_update        2025-02-05 
_em_admin.map_release_date   2025-02-05 
_em_admin.title              'Human TOP3B-TDRD3 complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         54.4 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 QUANTUM (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Cancer Institute (NIH/NCI)'                                         'United States' ? 1 
'National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK)' 'United States' ? 2 
# 
_atom_sites.entry_id                    9CAH 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
MN 
N  
O  
S  
ZN 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . HIS A 1 1   ? 131.449 151.142 207.692 1.00 75.06  0  0   HIS A N   1 
ATOM   2    C  CA  . HIS A 1 1   ? 132.843 150.949 207.309 1.00 75.06  0  0   HIS A CA  1 
ATOM   3    C  C   . HIS A 1 1   ? 133.051 151.290 205.837 1.00 75.06  0  0   HIS A C   1 
ATOM   4    O  O   . HIS A 1 1   ? 132.137 151.157 205.024 1.00 75.06  0  0   HIS A O   1 
ATOM   5    C  CB  . HIS A 1 1   ? 133.282 149.510 207.589 1.00 75.06  0  0   HIS A CB  1 
ATOM   6    C  CG  . HIS A 1 1   ? 134.747 149.275 207.390 1.00 75.06  0  0   HIS A CG  1 
ATOM   7    N  ND1 . HIS A 1 1   ? 135.294 148.986 206.158 1.00 75.06  0  0   HIS A ND1 1 
ATOM   8    C  CD2 . HIS A 1 1   ? 135.779 149.286 208.266 1.00 75.06  0  0   HIS A CD2 1 
ATOM   9    C  CE1 . HIS A 1 1   ? 136.599 148.829 206.285 1.00 75.06  0  0   HIS A CE1 1 
ATOM   10   N  NE2 . HIS A 1 1   ? 136.919 149.006 207.554 1.00 75.06  0  0   HIS A NE2 1 
ATOM   11   N  N   . MET A 1 2   ? 134.261 151.730 205.501 1.00 71.90  0  1   MET A N   1 
ATOM   12   C  CA  . MET A 1 2   ? 134.579 152.117 204.135 1.00 71.90  0  1   MET A CA  1 
ATOM   13   C  C   . MET A 1 2   ? 134.804 150.882 203.272 1.00 71.90  0  1   MET A C   1 
ATOM   14   O  O   . MET A 1 2   ? 135.578 149.992 203.636 1.00 71.90  0  1   MET A O   1 
ATOM   15   C  CB  . MET A 1 2   ? 135.819 153.010 204.112 1.00 71.90  0  1   MET A CB  1 
ATOM   16   C  CG  . MET A 1 2   ? 136.162 153.565 202.741 1.00 71.90  0  1   MET A CG  1 
ATOM   17   S  SD  . MET A 1 2   ? 137.624 154.620 202.768 1.00 71.90  0  1   MET A SD  1 
ATOM   18   C  CE  . MET A 1 2   ? 136.980 156.065 203.607 1.00 71.90  0  1   MET A CE  1 
ATOM   19   N  N   . LYS A 1 3   ? 134.127 150.831 202.130 1.00 67.28  0  2   LYS A N   1 
ATOM   20   C  CA  . LYS A 1 3   ? 134.299 149.745 201.181 1.00 67.28  0  2   LYS A CA  1 
ATOM   21   C  C   . LYS A 1 3   ? 135.236 150.177 200.053 1.00 67.28  0  2   LYS A C   1 
ATOM   22   O  O   . LYS A 1 3   ? 135.678 151.326 199.986 1.00 67.28  0  2   LYS A O   1 
ATOM   23   C  CB  . LYS A 1 3   ? 132.941 149.293 200.644 1.00 67.28  0  2   LYS A CB  1 
ATOM   24   C  CG  . LYS A 1 3   ? 132.269 150.277 199.715 1.00 67.28  0  2   LYS A CG  1 
ATOM   25   C  CD  . LYS A 1 3   ? 130.977 149.711 199.150 1.00 67.28  0  2   LYS A CD  1 
ATOM   26   C  CE  . LYS A 1 3   ? 130.060 149.207 200.252 1.00 67.28  0  2   LYS A CE  1 
ATOM   27   N  NZ  . LYS A 1 3   ? 128.629 149.261 199.846 1.00 67.28  1  2   LYS A NZ  1 
ATOM   28   N  N   . THR A 1 4   ? 135.539 149.239 199.156 1.00 67.28  0  3   THR A N   1 
ATOM   29   C  CA  . THR A 1 4   ? 136.623 149.415 198.201 1.00 67.28  0  3   THR A CA  1 
ATOM   30   C  C   . THR A 1 4   ? 136.144 149.217 196.770 1.00 67.28  0  3   THR A C   1 
ATOM   31   O  O   . THR A 1 4   ? 135.157 148.522 196.512 1.00 67.28  0  3   THR A O   1 
ATOM   32   C  CB  . THR A 1 4   ? 137.779 148.446 198.487 1.00 67.28  0  3   THR A CB  1 
ATOM   33   O  OG1 . THR A 1 4   ? 138.776 148.571 197.466 1.00 67.28  0  3   THR A OG1 1 
ATOM   34   C  CG2 . THR A 1 4   ? 137.277 147.015 198.529 1.00 67.28  0  3   THR A CG2 1 
ATOM   35   N  N   . VAL A 1 5   ? 136.865 149.848 195.844 1.00 67.28  0  4   VAL A N   1 
ATOM   36   C  CA  . VAL A 1 5   ? 136.620 149.748 194.410 1.00 67.28  0  4   VAL A CA  1 
ATOM   37   C  C   . VAL A 1 5   ? 137.945 149.424 193.734 1.00 67.28  0  4   VAL A C   1 
ATOM   38   O  O   . VAL A 1 5   ? 138.993 149.938 194.138 1.00 67.28  0  4   VAL A O   1 
ATOM   39   C  CB  . VAL A 1 5   ? 136.020 151.054 193.843 1.00 67.28  0  4   VAL A CB  1 
ATOM   40   C  CG1 . VAL A 1 5   ? 135.858 150.969 192.332 1.00 67.28  0  4   VAL A CG1 1 
ATOM   41   C  CG2 . VAL A 1 5   ? 134.690 151.368 194.511 1.00 67.28  0  4   VAL A CG2 1 
ATOM   42   N  N   . LEU A 1 6   ? 137.902 148.564 192.719 1.00 67.28  0  5   LEU A N   1 
ATOM   43   C  CA  . LEU A 1 6   ? 139.095 148.106 192.020 1.00 67.28  0  5   LEU A CA  1 
ATOM   44   C  C   . LEU A 1 6   ? 139.108 148.631 190.590 1.00 67.28  0  5   LEU A C   1 
ATOM   45   O  O   . LEU A 1 6   ? 138.060 148.738 189.945 1.00 67.28  0  5   LEU A O   1 
ATOM   46   C  CB  . LEU A 1 6   ? 139.175 146.575 192.023 1.00 67.28  0  5   LEU A CB  1 
ATOM   47   C  CG  . LEU A 1 6   ? 140.430 145.906 191.455 1.00 67.28  0  5   LEU A CG  1 
ATOM   48   C  CD1 . LEU A 1 6   ? 140.767 144.657 192.245 1.00 67.28  0  5   LEU A CD1 1 
ATOM   49   C  CD2 . LEU A 1 6   ? 140.240 145.551 189.991 1.00 67.28  0  5   LEU A CD2 1 
ATOM   50   N  N   . MET A 1 7   ? 140.303 148.960 190.103 1.00 67.28  0  6   MET A N   1 
ATOM   51   C  CA  . MET A 1 7   ? 140.509 149.465 188.753 1.00 67.28  0  6   MET A CA  1 
ATOM   52   C  C   . MET A 1 7   ? 141.584 148.647 188.055 1.00 67.28  0  6   MET A C   1 
ATOM   53   O  O   . MET A 1 7   ? 142.566 148.240 188.681 1.00 67.28  0  6   MET A O   1 
ATOM   54   C  CB  . MET A 1 7   ? 140.930 150.935 188.760 1.00 67.28  0  6   MET A CB  1 
ATOM   55   C  CG  . MET A 1 7   ? 140.071 151.842 189.606 1.00 67.28  0  6   MET A CG  1 
ATOM   56   S  SD  . MET A 1 7   ? 139.926 153.468 188.847 1.00 67.28  0  6   MET A SD  1 
ATOM   57   C  CE  . MET A 1 7   ? 138.743 154.235 189.939 1.00 67.28  0  6   MET A CE  1 
ATOM   58   N  N   . VAL A 1 8   ? 141.409 148.432 186.753 1.00 67.28  0  7   VAL A N   1 
ATOM   59   C  CA  . VAL A 1 8   ? 142.375 147.707 185.936 1.00 67.28  0  7   VAL A CA  1 
ATOM   60   C  C   . VAL A 1 8   ? 142.701 148.538 184.702 1.00 67.28  0  7   VAL A C   1 
ATOM   61   O  O   . VAL A 1 8   ? 141.794 148.992 183.997 1.00 67.28  0  7   VAL A O   1 
ATOM   62   C  CB  . VAL A 1 8   ? 141.850 146.318 185.527 1.00 67.28  0  7   VAL A CB  1 
ATOM   63   C  CG1 . VAL A 1 8   ? 142.738 145.707 184.455 1.00 67.28  0  7   VAL A CG1 1 
ATOM   64   C  CG2 . VAL A 1 8   ? 141.778 145.405 186.736 1.00 67.28  0  7   VAL A CG2 1 
ATOM   65   N  N   . ALA A 1 9   ? 143.991 148.736 184.447 1.00 67.28  0  8   ALA A N   1 
ATOM   66   C  CA  . ALA A 1 9   ? 144.479 149.386 183.240 1.00 67.28  0  8   ALA A CA  1 
ATOM   67   C  C   . ALA A 1 9   ? 145.272 148.389 182.401 1.00 67.28  0  8   ALA A C   1 
ATOM   68   O  O   . ALA A 1 9   ? 145.629 147.301 182.858 1.00 67.28  0  8   ALA A O   1 
ATOM   69   C  CB  . ALA A 1 9   ? 145.341 150.605 183.585 1.00 67.28  0  8   ALA A CB  1 
ATOM   70   N  N   . GLU A 1 10  ? 145.559 148.773 181.153 1.00 67.28  0  9   GLU A N   1 
ATOM   71   C  CA  . GLU A 1 10  ? 146.263 147.857 180.214 1.00 67.28  0  9   GLU A CA  1 
ATOM   72   C  C   . GLU A 1 10  ? 147.780 147.927 180.413 1.00 67.28  0  9   GLU A C   1 
ATOM   73   O  O   . GLU A 1 10  ? 148.462 146.968 180.009 1.00 67.28  0  9   GLU A O   1 
ATOM   74   C  CB  . GLU A 1 10  ? 145.918 148.231 178.773 1.00 67.28  0  9   GLU A CB  1 
ATOM   75   C  CG  . GLU A 1 10  ? 145.890 147.052 177.819 1.00 67.28  0  9   GLU A CG  1 
ATOM   76   C  CD  . GLU A 1 10  ? 145.087 147.304 176.555 1.00 67.28  0  9   GLU A CD  1 
ATOM   77   O  OE1 . GLU A 1 10  ? 143.920 147.724 176.673 1.00 67.28  0  9   GLU A OE1 1 
ATOM   78   O  OE2 . GLU A 1 10  ? 145.632 147.084 175.455 1.00 67.28  -1 9   GLU A OE2 1 
ATOM   79   N  N   . LYS A 1 11  ? 148.288 149.024 180.981 1.00 67.28  0  10  LYS A N   1 
ATOM   80   C  CA  . LYS A 1 11  ? 149.720 149.167 181.198 1.00 67.28  0  10  LYS A CA  1 
ATOM   81   C  C   . LYS A 1 11  ? 149.965 149.814 182.552 1.00 67.28  0  10  LYS A C   1 
ATOM   82   O  O   . LYS A 1 11  ? 149.153 150.627 183.010 1.00 67.28  0  10  LYS A O   1 
ATOM   83   C  CB  . LYS A 1 11  ? 150.381 150.007 180.093 1.00 67.28  0  10  LYS A CB  1 
ATOM   84   C  CG  . LYS A 1 11  ? 150.434 149.317 178.738 1.00 67.28  0  10  LYS A CG  1 
ATOM   85   C  CD  . LYS A 1 11  ? 150.918 150.256 177.647 1.00 67.28  0  10  LYS A CD  1 
ATOM   86   C  CE  . LYS A 1 11  ? 150.831 149.598 176.280 1.00 67.28  0  10  LYS A CE  1 
ATOM   87   N  NZ  . LYS A 1 11  ? 151.321 150.494 175.197 1.00 67.28  1  10  LYS A NZ  1 
ATOM   88   N  N   . PRO A 1 12  ? 151.064 149.456 183.225 1.00 67.28  0  11  PRO A N   1 
ATOM   89   C  CA  . PRO A 1 12  ? 151.362 150.091 184.522 1.00 67.28  0  11  PRO A CA  1 
ATOM   90   C  C   . PRO A 1 12  ? 151.551 151.594 184.432 1.00 67.28  0  11  PRO A C   1 
ATOM   91   O  O   . PRO A 1 12  ? 151.157 152.323 185.350 1.00 67.28  0  11  PRO A O   1 
ATOM   92   C  CB  . PRO A 1 12  ? 152.647 149.380 184.974 1.00 67.28  0  11  PRO A CB  1 
ATOM   93   C  CG  . PRO A 1 12  ? 153.204 148.743 183.738 1.00 67.28  0  11  PRO A CG  1 
ATOM   94   C  CD  . PRO A 1 12  ? 152.028 148.397 182.890 1.00 67.28  0  11  PRO A CD  1 
ATOM   95   N  N   . SER A 1 13  ? 152.148 152.081 183.343 1.00 67.28  0  12  SER A N   1 
ATOM   96   C  CA  . SER A 1 13  ? 152.309 153.520 183.169 1.00 67.28  0  12  SER A CA  1 
ATOM   97   C  C   . SER A 1 13  ? 150.960 154.213 183.013 1.00 67.28  0  12  SER A C   1 
ATOM   98   O  O   . SER A 1 13  ? 150.734 155.285 183.590 1.00 67.28  0  12  SER A O   1 
ATOM   99   C  CB  . SER A 1 13  ? 153.211 153.795 181.969 1.00 67.28  0  12  SER A CB  1 
ATOM   100  O  OG  . SER A 1 13  ? 152.603 153.344 180.776 1.00 67.28  0  12  SER A OG  1 
ATOM   101  N  N   . LEU A 1 14  ? 150.048 153.615 182.240 1.00 67.28  0  13  LEU A N   1 
ATOM   102  C  CA  . LEU A 1 14  ? 148.698 154.159 182.137 1.00 67.28  0  13  LEU A CA  1 
ATOM   103  C  C   . LEU A 1 14  ? 147.998 154.140 183.488 1.00 67.28  0  13  LEU A C   1 
ATOM   104  O  O   . LEU A 1 14  ? 147.284 155.086 183.841 1.00 67.28  0  13  LEU A O   1 
ATOM   105  C  CB  . LEU A 1 14  ? 147.884 153.374 181.109 1.00 67.28  0  13  LEU A CB  1 
ATOM   106  C  CG  . LEU A 1 14  ? 148.257 153.537 179.637 1.00 67.28  0  13  LEU A CG  1 
ATOM   107  C  CD1 . LEU A 1 14  ? 147.434 152.595 178.776 1.00 67.28  0  13  LEU A CD1 1 
ATOM   108  C  CD2 . LEU A 1 14  ? 148.042 154.974 179.204 1.00 67.28  0  13  LEU A CD2 1 
ATOM   109  N  N   . ALA A 1 15  ? 148.186 153.062 184.253 1.00 67.28  0  14  ALA A N   1 
ATOM   110  C  CA  . ALA A 1 15  ? 147.588 152.981 185.580 1.00 67.28  0  14  ALA A CA  1 
ATOM   111  C  C   . ALA A 1 15  ? 148.090 154.108 186.472 1.00 67.28  0  14  ALA A C   1 
ATOM   112  O  O   . ALA A 1 15  ? 147.303 154.782 187.144 1.00 67.28  0  14  ALA A O   1 
ATOM   113  C  CB  . ALA A 1 15  ? 147.886 151.619 186.208 1.00 67.28  0  14  ALA A CB  1 
ATOM   114  N  N   . GLN A 1 16  ? 149.404 154.338 186.470 1.00 67.28  0  15  GLN A N   1 
ATOM   115  C  CA  . GLN A 1 16  ? 149.979 155.407 187.280 1.00 67.28  0  15  GLN A CA  1 
ATOM   116  C  C   . GLN A 1 16  ? 149.461 156.771 186.842 1.00 67.28  0  15  GLN A C   1 
ATOM   117  O  O   . GLN A 1 16  ? 149.109 157.608 187.681 1.00 67.28  0  15  GLN A O   1 
ATOM   118  C  CB  . GLN A 1 16  ? 151.506 155.352 187.203 1.00 67.28  0  15  GLN A CB  1 
ATOM   119  C  CG  . GLN A 1 16  ? 152.237 156.293 188.153 1.00 67.28  0  15  GLN A CG  1 
ATOM   120  C  CD  . GLN A 1 16  ? 152.417 157.686 187.583 1.00 67.28  0  15  GLN A CD  1 
ATOM   121  O  OE1 . GLN A 1 16  ? 152.512 157.865 186.369 1.00 67.28  0  15  GLN A OE1 1 
ATOM   122  N  NE2 . GLN A 1 16  ? 152.470 158.682 188.460 1.00 67.28  0  15  GLN A NE2 1 
ATOM   123  N  N   . SER A 1 17  ? 149.396 157.009 185.529 1.00 67.28  0  16  SER A N   1 
ATOM   124  C  CA  . SER A 1 17  ? 148.942 158.305 185.033 1.00 67.28  0  16  SER A CA  1 
ATOM   125  C  C   . SER A 1 17  ? 147.490 158.566 185.417 1.00 67.28  0  16  SER A C   1 
ATOM   126  O  O   . SER A 1 17  ? 147.152 159.647 185.918 1.00 67.28  0  16  SER A O   1 
ATOM   127  C  CB  . SER A 1 17  ? 149.121 158.373 183.516 1.00 67.28  0  16  SER A CB  1 
ATOM   128  O  OG  . SER A 1 17  ? 149.104 159.714 183.060 1.00 67.28  0  16  SER A OG  1 
ATOM   129  N  N   . ILE A 1 18  ? 146.616 157.582 185.200 1.00 67.28  0  17  ILE A N   1 
ATOM   130  C  CA  . ILE A 1 18  ? 145.202 157.771 185.508 1.00 67.28  0  17  ILE A CA  1 
ATOM   131  C  C   . ILE A 1 18  ? 144.992 157.893 187.013 1.00 67.28  0  17  ILE A C   1 
ATOM   132  O  O   . ILE A 1 18  ? 144.144 158.668 187.473 1.00 67.28  0  17  ILE A O   1 
ATOM   133  C  CB  . ILE A 1 18  ? 144.367 156.630 184.900 1.00 67.28  0  17  ILE A CB  1 
ATOM   134  C  CG1 . ILE A 1 18  ? 144.511 156.618 183.378 1.00 67.28  0  17  ILE A CG1 1 
ATOM   135  C  CG2 . ILE A 1 18  ? 142.904 156.765 185.287 1.00 67.28  0  17  ILE A CG2 1 
ATOM   136  C  CD1 . ILE A 1 18  ? 144.110 155.309 182.739 1.00 67.28  0  17  ILE A CD1 1 
ATOM   137  N  N   . ALA A 1 19  ? 145.757 157.137 187.805 1.00 67.28  0  18  ALA A N   1 
ATOM   138  C  CA  . ALA A 1 19  ? 145.662 157.259 189.254 1.00 67.28  0  18  ALA A CA  1 
ATOM   139  C  C   . ALA A 1 19  ? 146.084 158.646 189.718 1.00 67.28  0  18  ALA A C   1 
ATOM   140  O  O   . ALA A 1 19  ? 145.461 159.222 190.615 1.00 67.28  0  18  ALA A O   1 
ATOM   141  C  CB  . ALA A 1 19  ? 146.512 156.182 189.927 1.00 67.28  0  18  ALA A CB  1 
ATOM   142  N  N   . LYS A 1 20  ? 147.143 159.197 189.120 1.00 67.28  0  19  LYS A N   1 
ATOM   143  C  CA  . LYS A 1 20  ? 147.554 160.554 189.463 1.00 67.28  0  19  LYS A CA  1 
ATOM   144  C  C   . LYS A 1 20  ? 146.487 161.569 189.074 1.00 67.28  0  19  LYS A C   1 
ATOM   145  O  O   . LYS A 1 20  ? 146.223 162.520 189.819 1.00 67.28  0  19  LYS A O   1 
ATOM   146  C  CB  . LYS A 1 20  ? 148.883 160.890 188.786 1.00 67.28  0  19  LYS A CB  1 
ATOM   147  C  CG  . LYS A 1 20  ? 149.488 162.209 189.237 1.00 67.28  0  19  LYS A CG  1 
ATOM   148  C  CD  . LYS A 1 20  ? 151.006 162.154 189.236 1.00 67.28  0  19  LYS A CD  1 
ATOM   149  C  CE  . LYS A 1 20  ? 151.545 161.877 187.842 1.00 67.28  0  19  LYS A CE  1 
ATOM   150  N  NZ  . LYS A 1 20  ? 151.360 163.043 186.935 1.00 67.28  1  19  LYS A NZ  1 
ATOM   151  N  N   . ILE A 1 21  ? 145.869 161.389 187.904 1.00 67.28  0  20  ILE A N   1 
ATOM   152  C  CA  . ILE A 1 21  ? 144.849 162.334 187.451 1.00 67.28  0  20  ILE A CA  1 
ATOM   153  C  C   . ILE A 1 21  ? 143.640 162.306 188.380 1.00 67.28  0  20  ILE A C   1 
ATOM   154  O  O   . ILE A 1 21  ? 143.126 163.354 188.790 1.00 67.28  0  20  ILE A O   1 
ATOM   155  C  CB  . ILE A 1 21  ? 144.448 162.041 185.994 1.00 67.28  0  20  ILE A CB  1 
ATOM   156  C  CG1 . ILE A 1 21  ? 145.643 162.238 185.061 1.00 67.28  0  20  ILE A CG1 1 
ATOM   157  C  CG2 . ILE A 1 21  ? 143.289 162.927 185.571 1.00 67.28  0  20  ILE A CG2 1 
ATOM   158  C  CD1 . ILE A 1 21  ? 145.413 161.727 183.657 1.00 67.28  0  20  ILE A CD1 1 
ATOM   159  N  N   . LEU A 1 22  ? 143.169 161.108 188.730 1.00 67.28  0  21  LEU A N   1 
ATOM   160  C  CA  . LEU A 1 22  ? 141.957 160.996 189.537 1.00 67.28  0  21  LEU A CA  1 
ATOM   161  C  C   . LEU A 1 22  ? 142.198 161.308 191.008 1.00 67.28  0  21  LEU A C   1 
ATOM   162  O  O   . LEU A 1 22  ? 141.308 161.850 191.673 1.00 67.28  0  21  LEU A O   1 
ATOM   163  C  CB  . LEU A 1 22  ? 141.357 159.597 189.399 1.00 67.28  0  21  LEU A CB  1 
ATOM   164  C  CG  . LEU A 1 22  ? 140.495 159.345 188.163 1.00 67.28  0  21  LEU A CG  1 
ATOM   165  C  CD1 . LEU A 1 22  ? 140.435 157.861 187.844 1.00 67.28  0  21  LEU A CD1 1 
ATOM   166  C  CD2 . LEU A 1 22  ? 139.098 159.912 188.359 1.00 67.28  0  21  LEU A CD2 1 
ATOM   167  N  N   . SER A 1 23  ? 143.377 160.982 191.534 1.00 67.28  0  22  SER A N   1 
ATOM   168  C  CA  . SER A 1 23  ? 143.641 161.107 192.960 1.00 67.28  0  22  SER A CA  1 
ATOM   169  C  C   . SER A 1 23  ? 144.049 162.512 193.379 1.00 67.28  0  22  SER A C   1 
ATOM   170  O  O   . SER A 1 23  ? 144.162 162.767 194.583 1.00 67.28  0  22  SER A O   1 
ATOM   171  C  CB  . SER A 1 23  ? 144.730 160.114 193.372 1.00 67.28  0  22  SER A CB  1 
ATOM   172  O  OG  . SER A 1 23  ? 146.013 160.570 192.978 1.00 67.28  0  22  SER A OG  1 
ATOM   173  N  N   . ARG A 1 24  ? 144.266 163.420 192.425 1.00 67.28  0  23  ARG A N   1 
ATOM   174  C  CA  . ARG A 1 24  ? 144.659 164.800 192.718 1.00 67.28  0  23  ARG A CA  1 
ATOM   175  C  C   . ARG A 1 24  ? 145.923 164.855 193.575 1.00 67.28  0  23  ARG A C   1 
ATOM   176  O  O   . ARG A 1 24  ? 146.002 165.604 194.551 1.00 67.28  0  23  ARG A O   1 
ATOM   177  C  CB  . ARG A 1 24  ? 143.518 165.572 193.384 1.00 67.28  0  23  ARG A CB  1 
ATOM   178  C  CG  . ARG A 1 24  ? 142.573 166.255 192.410 1.00 67.28  0  23  ARG A CG  1 
ATOM   179  C  CD  . ARG A 1 24  ? 141.543 165.287 191.856 1.00 67.28  0  23  ARG A CD  1 
ATOM   180  N  NE  . ARG A 1 24  ? 140.622 165.944 190.936 1.00 67.28  0  23  ARG A NE  1 
ATOM   181  C  CZ  . ARG A 1 24  ? 139.500 166.548 191.303 1.00 67.28  0  23  ARG A CZ  1 
ATOM   182  N  NH1 . ARG A 1 24  ? 139.126 166.600 192.571 1.00 67.28  1  23  ARG A NH1 1 
ATOM   183  N  NH2 . ARG A 1 24  ? 138.735 167.116 190.375 1.00 67.28  0  23  ARG A NH2 1 
ATOM   184  N  N   . GLY A 1 25  ? 146.920 164.055 193.208 1.00 67.28  0  24  GLY A N   1 
ATOM   185  C  CA  . GLY A 1 25  ? 148.194 164.069 193.900 1.00 67.28  0  24  GLY A CA  1 
ATOM   186  C  C   . GLY A 1 25  ? 148.323 163.047 195.010 1.00 67.28  0  24  GLY A C   1 
ATOM   187  O  O   . GLY A 1 25  ? 149.258 162.241 195.005 1.00 67.28  0  24  GLY A O   1 
ATOM   188  N  N   . SER A 1 26  ? 147.400 163.071 195.973 1.00 67.28  0  25  SER A N   1 
ATOM   189  C  CA  . SER A 1 26  ? 147.441 162.129 197.085 1.00 67.28  0  25  SER A CA  1 
ATOM   190  C  C   . SER A 1 26  ? 147.271 160.704 196.578 1.00 67.28  0  25  SER A C   1 
ATOM   191  O  O   . SER A 1 26  ? 146.179 160.317 196.152 1.00 67.28  0  25  SER A O   1 
ATOM   192  C  CB  . SER A 1 26  ? 146.357 162.462 198.112 1.00 67.28  0  25  SER A CB  1 
ATOM   193  O  OG  . SER A 1 26  ? 146.127 161.367 198.982 1.00 67.28  0  25  SER A OG  1 
ATOM   194  N  N   . LEU A 1 27  ? 148.340 159.911 196.634 1.00 67.28  0  26  LEU A N   1 
ATOM   195  C  CA  . LEU A 1 27  ? 148.327 158.590 196.011 1.00 67.28  0  26  LEU A CA  1 
ATOM   196  C  C   . LEU A 1 27  ? 149.403 157.729 196.657 1.00 67.28  0  26  LEU A C   1 
ATOM   197  O  O   . LEU A 1 27  ? 150.594 158.022 196.513 1.00 67.28  0  26  LEU A O   1 
ATOM   198  C  CB  . LEU A 1 27  ? 148.553 158.710 194.509 1.00 67.28  0  26  LEU A CB  1 
ATOM   199  C  CG  . LEU A 1 27  ? 148.516 157.414 193.703 1.00 67.28  0  26  LEU A CG  1 
ATOM   200  C  CD1 . LEU A 1 27  ? 147.082 157.031 193.404 1.00 67.28  0  26  LEU A CD1 1 
ATOM   201  C  CD2 . LEU A 1 27  ? 149.316 157.556 192.419 1.00 67.28  0  26  LEU A CD2 1 
ATOM   202  N  N   . SER A 1 28  ? 148.989 156.679 197.359 1.00 67.28  0  27  SER A N   1 
ATOM   203  C  CA  . SER A 1 28  ? 149.926 155.676 197.838 1.00 67.28  0  27  SER A CA  1 
ATOM   204  C  C   . SER A 1 28  ? 150.157 154.642 196.745 1.00 67.28  0  27  SER A C   1 
ATOM   205  O  O   . SER A 1 28  ? 149.260 154.345 195.956 1.00 67.28  0  27  SER A O   1 
ATOM   206  C  CB  . SER A 1 28  ? 149.403 154.997 199.105 1.00 67.28  0  27  SER A CB  1 
ATOM   207  O  OG  . SER A 1 28  ? 149.200 155.942 200.141 1.00 67.28  0  27  SER A OG  1 
ATOM   208  N  N   . SER A 1 29  ? 151.370 154.101 196.692 1.00 67.28  0  28  SER A N   1 
ATOM   209  C  CA  . SER A 1 29  ? 151.702 153.142 195.648 1.00 67.28  0  28  SER A CA  1 
ATOM   210  C  C   . SER A 1 29  ? 152.690 152.120 196.184 1.00 67.28  0  28  SER A C   1 
ATOM   211  O  O   . SER A 1 29  ? 153.613 152.469 196.925 1.00 67.28  0  28  SER A O   1 
ATOM   212  C  CB  . SER A 1 29  ? 152.286 153.841 194.415 1.00 67.28  0  28  SER A CB  1 
ATOM   213  O  OG  . SER A 1 29  ? 153.568 154.376 194.691 1.00 67.28  0  28  SER A OG  1 
ATOM   214  N  N   . HIS A 1 30  ? 152.493 150.858 195.805 1.00 67.28  0  29  HIS A N   1 
ATOM   215  C  CA  . HIS A 1 30  ? 153.454 149.822 196.160 1.00 67.28  0  29  HIS A CA  1 
ATOM   216  C  C   . HIS A 1 30  ? 153.406 148.702 195.132 1.00 67.28  0  29  HIS A C   1 
ATOM   217  O  O   . HIS A 1 30  ? 152.368 148.444 194.519 1.00 67.28  0  29  HIS A O   1 
ATOM   218  C  CB  . HIS A 1 30  ? 153.213 149.277 197.575 1.00 67.28  0  29  HIS A CB  1 
ATOM   219  C  CG  . HIS A 1 30  ? 151.819 148.788 197.814 1.00 67.28  0  29  HIS A CG  1 
ATOM   220  N  ND1 . HIS A 1 30  ? 151.500 147.449 197.873 1.00 67.28  0  29  HIS A ND1 1 
ATOM   221  C  CD2 . HIS A 1 30  ? 150.662 149.460 198.024 1.00 67.28  0  29  HIS A CD2 1 
ATOM   222  C  CE1 . HIS A 1 30  ? 150.206 147.316 198.107 1.00 67.28  0  29  HIS A CE1 1 
ATOM   223  N  NE2 . HIS A 1 30  ? 149.674 148.521 198.199 1.00 67.28  0  29  HIS A NE2 1 
ATOM   224  N  N   . LYS A 1 31  ? 154.547 148.044 194.948 1.00 68.76  0  30  LYS A N   1 
ATOM   225  C  CA  . LYS A 1 31  ? 154.674 147.028 193.915 1.00 68.76  0  30  LYS A CA  1 
ATOM   226  C  C   . LYS A 1 31  ? 153.893 145.770 194.278 1.00 68.76  0  30  LYS A C   1 
ATOM   227  O  O   . LYS A 1 31  ? 153.704 145.442 195.453 1.00 68.76  0  30  LYS A O   1 
ATOM   228  C  CB  . LYS A 1 31  ? 156.145 146.677 193.691 1.00 68.76  0  30  LYS A CB  1 
ATOM   229  C  CG  . LYS A 1 31  ? 156.795 147.429 192.543 1.00 68.76  0  30  LYS A CG  1 
ATOM   230  C  CD  . LYS A 1 31  ? 158.291 147.173 192.497 1.00 68.76  0  30  LYS A CD  1 
ATOM   231  C  CE  . LYS A 1 31  ? 158.997 147.813 193.682 1.00 68.76  0  30  LYS A CE  1 
ATOM   232  N  NZ  . LYS A 1 31  ? 160.359 147.250 193.885 1.00 68.76  1  30  LYS A NZ  1 
ATOM   233  N  N   . GLY A 1 32  ? 153.433 145.062 193.244 1.00 73.99  0  31  GLY A N   1 
ATOM   234  C  CA  . GLY A 1 32  ? 152.757 143.797 193.423 1.00 73.99  0  31  GLY A CA  1 
ATOM   235  C  C   . GLY A 1 32  ? 153.729 142.632 193.489 1.00 73.99  0  31  GLY A C   1 
ATOM   236  O  O   . GLY A 1 32  ? 154.944 142.781 193.364 1.00 73.99  0  31  GLY A O   1 
ATOM   237  N  N   . LEU A 1 33  ? 153.165 141.439 193.691 1.00 75.64  0  32  LEU A N   1 
ATOM   238  C  CA  . LEU A 1 33  ? 153.986 140.240 193.794 1.00 75.64  0  32  LEU A CA  1 
ATOM   239  C  C   . LEU A 1 33  ? 154.548 139.798 192.449 1.00 75.64  0  32  LEU A C   1 
ATOM   240  O  O   . LEU A 1 33  ? 155.500 139.011 192.420 1.00 75.64  0  32  LEU A O   1 
ATOM   241  C  CB  . LEU A 1 33  ? 153.180 139.104 194.431 1.00 75.64  0  32  LEU A CB  1 
ATOM   242  C  CG  . LEU A 1 33  ? 151.853 138.688 193.788 1.00 75.64  0  32  LEU A CG  1 
ATOM   243  C  CD1 . LEU A 1 33  ? 152.045 137.595 192.744 1.00 75.64  0  32  LEU A CD1 1 
ATOM   244  C  CD2 . LEU A 1 33  ? 150.874 138.238 194.859 1.00 75.64  0  32  LEU A CD2 1 
ATOM   245  N  N   . ASN A 1 34  ? 153.986 140.280 191.340 1.00 75.16  0  33  ASN A N   1 
ATOM   246  C  CA  . ASN A 1 34  ? 154.473 139.887 190.024 1.00 75.16  0  33  ASN A CA  1 
ATOM   247  C  C   . ASN A 1 34  ? 155.782 140.567 189.645 1.00 75.16  0  33  ASN A C   1 
ATOM   248  O  O   . ASN A 1 34  ? 156.484 140.075 188.755 1.00 75.16  0  33  ASN A O   1 
ATOM   249  C  CB  . ASN A 1 34  ? 153.401 140.164 188.964 1.00 75.16  0  33  ASN A CB  1 
ATOM   250  C  CG  . ASN A 1 34  ? 153.069 141.643 188.822 1.00 75.16  0  33  ASN A CG  1 
ATOM   251  O  OD1 . ASN A 1 34  ? 153.710 142.507 189.421 1.00 75.16  0  33  ASN A OD1 1 
ATOM   252  N  ND2 . ASN A 1 34  ? 152.053 141.936 188.020 1.00 75.16  0  33  ASN A ND2 1 
ATOM   253  N  N   . GLY A 1 35  ? 156.126 141.677 190.294 1.00 75.52  0  34  GLY A N   1 
ATOM   254  C  CA  . GLY A 1 35  ? 157.374 142.361 190.034 1.00 75.52  0  34  GLY A CA  1 
ATOM   255  C  C   . GLY A 1 35  ? 157.352 143.336 188.878 1.00 75.52  0  34  GLY A C   1 
ATOM   256  O  O   . GLY A 1 35  ? 158.360 144.017 188.648 1.00 75.52  0  34  GLY A O   1 
ATOM   257  N  N   . ALA A 1 36  ? 156.244 143.430 188.146 1.00 73.35  0  35  ALA A N   1 
ATOM   258  C  CA  . ALA A 1 36  ? 156.139 144.349 187.020 1.00 73.35  0  35  ALA A CA  1 
ATOM   259  C  C   . ALA A 1 36  ? 154.965 145.310 187.106 1.00 73.35  0  35  ALA A C   1 
ATOM   260  O  O   . ALA A 1 36  ? 154.975 146.322 186.394 1.00 73.35  0  35  ALA A O   1 
ATOM   261  C  CB  . ALA A 1 36  ? 156.041 143.572 185.698 1.00 73.35  0  35  ALA A CB  1 
ATOM   262  N  N   . CYS A 1 37  ? 153.964 145.041 187.939 1.00 71.18  0  36  CYS A N   1 
ATOM   263  C  CA  . CYS A 1 37  ? 152.804 145.906 188.088 1.00 71.18  0  36  CYS A CA  1 
ATOM   264  C  C   . CYS A 1 37  ? 152.737 146.432 189.514 1.00 71.18  0  36  CYS A C   1 
ATOM   265  O  O   . CYS A 1 37  ? 153.014 145.701 190.470 1.00 71.18  0  36  CYS A O   1 
ATOM   266  C  CB  . CYS A 1 37  ? 151.510 145.164 187.744 1.00 71.18  0  36  CYS A CB  1 
ATOM   267  S  SG  . CYS A 1 37  ? 151.504 144.391 186.111 1.00 71.18  0  36  CYS A SG  1 
ATOM   268  N  N   . SER A 1 38  ? 152.368 147.702 189.649 1.00 67.28  0  37  SER A N   1 
ATOM   269  C  CA  . SER A 1 38  ? 152.245 148.354 190.942 1.00 67.28  0  37  SER A CA  1 
ATOM   270  C  C   . SER A 1 38  ? 150.794 148.747 191.179 1.00 67.28  0  37  SER A C   1 
ATOM   271  O  O   . SER A 1 38  ? 150.064 149.082 190.241 1.00 67.28  0  37  SER A O   1 
ATOM   272  C  CB  . SER A 1 38  ? 153.143 149.595 191.026 1.00 67.28  0  37  SER A CB  1 
ATOM   273  O  OG  . SER A 1 38  ? 153.335 149.998 192.370 1.00 67.28  0  37  SER A OG  1 
ATOM   274  N  N   . VAL A 1 39  ? 150.380 148.706 192.442 1.00 67.28  0  38  VAL A N   1 
ATOM   275  C  CA  . VAL A 1 39  ? 149.016 149.027 192.838 1.00 67.28  0  38  VAL A CA  1 
ATOM   276  C  C   . VAL A 1 39  ? 149.018 150.368 193.558 1.00 67.28  0  38  VAL A C   1 
ATOM   277  O  O   . VAL A 1 39  ? 149.896 150.645 194.389 1.00 67.28  0  38  VAL A O   1 
ATOM   278  C  CB  . VAL A 1 39  ? 148.401 147.921 193.718 1.00 67.28  0  38  VAL A CB  1 
ATOM   279  C  CG1 . VAL A 1 39  ? 148.175 146.666 192.898 1.00 67.28  0  38  VAL A CG1 1 
ATOM   280  C  CG2 . VAL A 1 39  ? 149.296 147.616 194.898 1.00 67.28  0  38  VAL A CG2 1 
ATOM   281  N  N   . HIS A 1 40  ? 148.039 151.204 193.221 1.00 67.28  0  39  HIS A N   1 
ATOM   282  C  CA  . HIS A 1 40  ? 147.895 152.540 193.778 1.00 67.28  0  39  HIS A CA  1 
ATOM   283  C  C   . HIS A 1 40  ? 146.581 152.640 194.539 1.00 67.28  0  39  HIS A C   1 
ATOM   284  O  O   . HIS A 1 40  ? 145.556 152.105 194.105 1.00 67.28  0  39  HIS A O   1 
ATOM   285  C  CB  . HIS A 1 40  ? 147.949 153.603 192.677 1.00 67.28  0  39  HIS A CB  1 
ATOM   286  C  CG  . HIS A 1 40  ? 148.999 153.348 191.641 1.00 67.28  0  39  HIS A CG  1 
ATOM   287  N  ND1 . HIS A 1 40  ? 150.228 153.972 191.659 1.00 67.28  0  39  HIS A ND1 1 
ATOM   288  C  CD2 . HIS A 1 40  ? 149.003 152.542 190.553 1.00 67.28  0  39  HIS A CD2 1 
ATOM   289  C  CE1 . HIS A 1 40  ? 150.944 153.558 190.629 1.00 67.28  0  39  HIS A CE1 1 
ATOM   290  N  NE2 . HIS A 1 40  ? 150.224 152.691 189.942 1.00 67.28  0  39  HIS A NE2 1 
ATOM   291  N  N   . GLU A 1 41  ? 146.620 153.327 195.677 1.00 67.28  0  40  GLU A N   1 
ATOM   292  C  CA  . GLU A 1 41  ? 145.477 153.461 196.565 1.00 67.28  0  40  GLU A CA  1 
ATOM   293  C  C   . GLU A 1 41  ? 145.275 154.919 196.950 1.00 67.28  0  40  GLU A C   1 
ATOM   294  O  O   . GLU A 1 41  ? 146.237 155.680 197.113 1.00 67.28  0  40  GLU A O   1 
ATOM   295  C  CB  . GLU A 1 41  ? 145.651 152.620 197.838 1.00 67.28  0  40  GLU A CB  1 
ATOM   296  C  CG  . GLU A 1 41  ? 146.067 151.180 197.593 1.00 67.28  0  40  GLU A CG  1 
ATOM   297  C  CD  . GLU A 1 41  ? 146.118 150.366 198.870 1.00 67.28  0  40  GLU A CD  1 
ATOM   298  O  OE1 . GLU A 1 41  ? 145.293 150.623 199.772 1.00 67.28  0  40  GLU A OE1 1 
ATOM   299  O  OE2 . GLU A 1 41  ? 146.983 149.472 198.973 1.00 67.28  -1 40  GLU A OE2 1 
ATOM   300  N  N   . TYR A 1 42  ? 144.007 155.293 197.096 1.00 67.28  0  41  TYR A N   1 
ATOM   301  C  CA  . TYR A 1 42  ? 143.609 156.601 197.603 1.00 67.28  0  41  TYR A CA  1 
ATOM   302  C  C   . TYR A 1 42  ? 142.157 156.501 198.058 1.00 67.28  0  41  TYR A C   1 
ATOM   303  O  O   . TYR A 1 42  ? 141.569 155.417 198.082 1.00 67.28  0  41  TYR A O   1 
ATOM   304  C  CB  . TYR A 1 42  ? 143.812 157.705 196.559 1.00 67.28  0  41  TYR A CB  1 
ATOM   305  C  CG  . TYR A 1 42  ? 143.210 157.440 195.195 1.00 67.28  0  41  TYR A CG  1 
ATOM   306  C  CD1 . TYR A 1 42  ? 143.786 156.529 194.320 1.00 67.28  0  41  TYR A CD1 1 
ATOM   307  C  CD2 . TYR A 1 42  ? 142.083 158.129 194.771 1.00 67.28  0  41  TYR A CD2 1 
ATOM   308  C  CE1 . TYR A 1 42  ? 143.246 156.295 193.073 1.00 67.28  0  41  TYR A CE1 1 
ATOM   309  C  CE2 . TYR A 1 42  ? 141.538 157.904 193.523 1.00 67.28  0  41  TYR A CE2 1 
ATOM   310  C  CZ  . TYR A 1 42  ? 142.123 156.985 192.678 1.00 67.28  0  41  TYR A CZ  1 
ATOM   311  O  OH  . TYR A 1 42  ? 141.584 156.755 191.434 1.00 67.28  0  41  TYR A OH  1 
ATOM   312  N  N   . THR A 1 43  ? 141.583 157.641 198.433 1.00 67.28  0  42  THR A N   1 
ATOM   313  C  CA  . THR A 1 43  ? 140.226 157.692 198.962 1.00 67.28  0  42  THR A CA  1 
ATOM   314  C  C   . THR A 1 43  ? 139.411 158.701 198.168 1.00 67.28  0  42  THR A C   1 
ATOM   315  O  O   . THR A 1 43  ? 139.880 159.814 197.911 1.00 67.28  0  42  THR A O   1 
ATOM   316  C  CB  . THR A 1 43  ? 140.225 158.066 200.448 1.00 67.28  0  42  THR A CB  1 
ATOM   317  O  OG1 . THR A 1 43  ? 141.070 157.162 201.169 1.00 67.28  0  42  THR A OG1 1 
ATOM   318  C  CG2 . THR A 1 43  ? 138.817 157.994 201.016 1.00 67.28  0  42  THR A CG2 1 
ATOM   319  N  N   . GLY A 1 44  ? 138.201 158.318 197.784 1.00 67.28  0  43  GLY A N   1 
ATOM   320  C  CA  . GLY A 1 44  ? 137.324 159.181 197.013 1.00 67.28  0  43  GLY A CA  1 
ATOM   321  C  C   . GLY A 1 44  ? 135.881 158.811 197.249 1.00 67.28  0  43  GLY A C   1 
ATOM   322  O  O   . GLY A 1 44  ? 135.534 158.249 198.292 1.00 67.28  0  43  GLY A O   1 
ATOM   323  N  N   . THR A 1 45  ? 135.031 159.117 196.273 1.00 67.28  0  44  THR A N   1 
ATOM   324  C  CA  . THR A 1 45  ? 133.608 158.834 196.367 1.00 67.28  0  44  THR A CA  1 
ATOM   325  C  C   . THR A 1 45  ? 133.144 158.077 195.132 1.00 67.28  0  44  THR A C   1 
ATOM   326  O  O   . THR A 1 45  ? 133.506 158.425 194.005 1.00 67.28  0  44  THR A O   1 
ATOM   327  C  CB  . THR A 1 45  ? 132.788 160.121 196.520 1.00 67.28  0  44  THR A CB  1 
ATOM   328  O  OG1 . THR A 1 45  ? 133.164 161.055 195.500 1.00 67.28  0  44  THR A OG1 1 
ATOM   329  C  CG2 . THR A 1 45  ? 133.023 160.745 197.886 1.00 67.28  0  44  THR A CG2 1 
ATOM   330  N  N   . PHE A 1 46  ? 132.339 157.041 195.357 1.00 67.28  0  45  PHE A N   1 
ATOM   331  C  CA  . PHE A 1 46  ? 131.709 156.275 194.293 1.00 67.28  0  45  PHE A CA  1 
ATOM   332  C  C   . PHE A 1 46  ? 130.234 156.107 194.619 1.00 67.28  0  45  PHE A C   1 
ATOM   333  O  O   . PHE A 1 46  ? 129.857 155.958 195.785 1.00 67.28  0  45  PHE A O   1 
ATOM   334  C  CB  . PHE A 1 46  ? 132.365 154.901 194.117 1.00 67.28  0  45  PHE A CB  1 
ATOM   335  C  CG  . PHE A 1 46  ? 132.308 154.373 192.714 1.00 67.28  0  45  PHE A CG  1 
ATOM   336  C  CD1 . PHE A 1 46  ? 132.864 155.086 191.668 1.00 67.28  0  45  PHE A CD1 1 
ATOM   337  C  CD2 . PHE A 1 46  ? 131.704 153.158 192.445 1.00 67.28  0  45  PHE A CD2 1 
ATOM   338  C  CE1 . PHE A 1 46  ? 132.814 154.598 190.379 1.00 67.28  0  45  PHE A CE1 1 
ATOM   339  C  CE2 . PHE A 1 46  ? 131.651 152.666 191.159 1.00 67.28  0  45  PHE A CE2 1 
ATOM   340  C  CZ  . PHE A 1 46  ? 132.207 153.386 190.125 1.00 67.28  0  45  PHE A CZ  1 
ATOM   341  N  N   . ALA A 1 47  ? 129.404 156.126 193.574 1.00 67.28  0  46  ALA A N   1 
ATOM   342  C  CA  . ALA A 1 47  ? 127.955 156.092 193.732 1.00 67.28  0  46  ALA A CA  1 
ATOM   343  C  C   . ALA A 1 47  ? 127.509 157.192 194.687 1.00 67.28  0  46  ALA A C   1 
ATOM   344  O  O   . ALA A 1 47  ? 127.347 158.347 194.282 1.00 67.28  0  46  ALA A O   1 
ATOM   345  C  CB  . ALA A 1 47  ? 127.488 154.720 194.227 1.00 67.28  0  46  ALA A CB  1 
ATOM   346  N  N   . GLY A 1 48  ? 127.307 156.840 195.954 1.00 67.28  0  47  GLY A N   1 
ATOM   347  C  CA  . GLY A 1 48  ? 126.976 157.823 196.965 1.00 67.28  0  47  GLY A CA  1 
ATOM   348  C  C   . GLY A 1 48  ? 127.642 157.557 198.299 1.00 67.28  0  47  GLY A C   1 
ATOM   349  O  O   . GLY A 1 48  ? 127.142 157.988 199.342 1.00 67.28  0  47  GLY A O   1 
ATOM   350  N  N   . GLN A 1 49  ? 128.767 156.848 198.283 1.00 67.28  0  48  GLN A N   1 
ATOM   351  C  CA  . GLN A 1 49  ? 129.459 156.470 199.503 1.00 67.28  0  48  GLN A CA  1 
ATOM   352  C  C   . GLN A 1 49  ? 130.930 156.849 199.419 1.00 67.28  0  48  GLN A C   1 
ATOM   353  O  O   . GLN A 1 49  ? 131.510 156.870 198.329 1.00 67.28  0  48  GLN A O   1 
ATOM   354  C  CB  . GLN A 1 49  ? 129.347 154.960 199.768 1.00 67.28  0  48  GLN A CB  1 
ATOM   355  C  CG  . GLN A 1 49  ? 127.974 154.470 200.225 1.00 67.28  0  48  GLN A CG  1 
ATOM   356  C  CD  . GLN A 1 49  ? 126.920 154.542 199.136 1.00 67.28  0  48  GLN A CD  1 
ATOM   357  O  OE1 . GLN A 1 49  ? 125.910 155.231 199.278 1.00 67.28  0  48  GLN A OE1 1 
ATOM   358  N  NE2 . GLN A 1 49  ? 127.153 153.830 198.040 1.00 67.28  0  48  GLN A NE2 1 
ATOM   359  N  N   . PRO A 1 50  ? 131.559 157.154 200.558 1.00 67.28  0  49  PRO A N   1 
ATOM   360  C  CA  . PRO A 1 50  ? 133.013 157.377 200.579 1.00 67.28  0  49  PRO A CA  1 
ATOM   361  C  C   . PRO A 1 50  ? 133.745 156.042 200.572 1.00 67.28  0  49  PRO A C   1 
ATOM   362  O  O   . PRO A 1 50  ? 133.547 155.210 201.461 1.00 67.28  0  49  PRO A O   1 
ATOM   363  C  CB  . PRO A 1 50  ? 133.235 158.138 201.890 1.00 67.28  0  49  PRO A CB  1 
ATOM   364  C  CG  . PRO A 1 50  ? 132.113 157.694 202.768 1.00 67.28  0  49  PRO A CG  1 
ATOM   365  C  CD  . PRO A 1 50  ? 130.937 157.416 201.868 1.00 67.28  0  49  PRO A CD  1 
ATOM   366  N  N   . VAL A 1 51  ? 134.589 155.833 199.563 1.00 67.28  0  50  VAL A N   1 
ATOM   367  C  CA  . VAL A 1 51  ? 135.179 154.524 199.314 1.00 67.28  0  50  VAL A CA  1 
ATOM   368  C  C   . VAL A 1 51  ? 136.670 154.650 199.028 1.00 67.28  0  50  VAL A C   1 
ATOM   369  O  O   . VAL A 1 51  ? 137.157 155.685 198.559 1.00 67.28  0  50  VAL A O   1 
ATOM   370  C  CB  . VAL A 1 51  ? 134.474 153.808 198.143 1.00 67.28  0  50  VAL A CB  1 
ATOM   371  C  CG1 . VAL A 1 51  ? 133.040 153.474 198.508 1.00 67.28  0  50  VAL A CG1 1 
ATOM   372  C  CG2 . VAL A 1 51  ? 134.505 154.678 196.913 1.00 67.28  0  50  VAL A CG2 1 
ATOM   373  N  N   . ARG A 1 52  ? 137.388 153.563 199.294 1.00 67.28  0  51  ARG A N   1 
ATOM   374  C  CA  . ARG A 1 52  ? 138.795 153.441 198.948 1.00 67.28  0  51  ARG A CA  1 
ATOM   375  C  C   . ARG A 1 52  ? 138.937 152.918 197.525 1.00 67.28  0  51  ARG A C   1 
ATOM   376  O  O   . ARG A 1 52  ? 138.062 152.216 197.010 1.00 67.28  0  51  ARG A O   1 
ATOM   377  C  CB  . ARG A 1 52  ? 139.512 152.504 199.921 1.00 67.28  0  51  ARG A CB  1 
ATOM   378  C  CG  . ARG A 1 52  ? 141.012 152.725 200.012 1.00 67.28  0  51  ARG A CG  1 
ATOM   379  C  CD  . ARG A 1 52  ? 141.625 151.900 201.131 1.00 67.28  0  51  ARG A CD  1 
ATOM   380  N  NE  . ARG A 1 52  ? 141.068 150.553 201.186 1.00 67.28  0  51  ARG A NE  1 
ATOM   381  C  CZ  . ARG A 1 52  ? 141.739 149.452 200.880 1.00 67.28  0  51  ARG A CZ  1 
ATOM   382  N  NH1 . ARG A 1 52  ? 143.002 149.498 200.489 1.00 67.28  1  51  ARG A NH1 1 
ATOM   383  N  NH2 . ARG A 1 52  ? 141.128 148.274 200.966 1.00 67.28  0  51  ARG A NH2 1 
ATOM   384  N  N   . PHE A 1 53  ? 140.048 153.272 196.887 1.00 67.28  0  52  PHE A N   1 
ATOM   385  C  CA  . PHE A 1 53  ? 140.324 152.882 195.515 1.00 67.28  0  52  PHE A CA  1 
ATOM   386  C  C   . PHE A 1 53  ? 141.573 152.013 195.474 1.00 67.28  0  52  PHE A C   1 
ATOM   387  O  O   . PHE A 1 53  ? 142.478 152.157 196.301 1.00 67.28  0  52  PHE A O   1 
ATOM   388  C  CB  . PHE A 1 53  ? 140.516 154.110 194.608 1.00 67.28  0  52  PHE A CB  1 
ATOM   389  C  CG  . PHE A 1 53  ? 139.230 154.788 194.205 1.00 67.28  0  52  PHE A CG  1 
ATOM   390  C  CD1 . PHE A 1 53  ? 138.081 154.656 194.960 1.00 67.28  0  52  PHE A CD1 1 
ATOM   391  C  CD2 . PHE A 1 53  ? 139.181 155.575 193.069 1.00 67.28  0  52  PHE A CD2 1 
ATOM   392  C  CE1 . PHE A 1 53  ? 136.912 155.286 194.585 1.00 67.28  0  52  PHE A CE1 1 
ATOM   393  C  CE2 . PHE A 1 53  ? 138.014 156.209 192.692 1.00 67.28  0  52  PHE A CE2 1 
ATOM   394  C  CZ  . PHE A 1 53  ? 136.879 156.062 193.450 1.00 67.28  0  52  PHE A CZ  1 
ATOM   395  N  N   . LYS A 1 54  ? 141.611 151.102 194.502 1.00 67.28  0  53  LYS A N   1 
ATOM   396  C  CA  . LYS A 1 54  ? 142.742 150.191 194.339 1.00 67.28  0  53  LYS A CA  1 
ATOM   397  C  C   . LYS A 1 54  ? 142.922 149.978 192.840 1.00 67.28  0  53  LYS A C   1 
ATOM   398  O  O   . LYS A 1 54  ? 142.225 149.152 192.244 1.00 67.28  0  53  LYS A O   1 
ATOM   399  C  CB  . LYS A 1 54  ? 142.494 148.876 195.064 1.00 67.28  0  53  LYS A CB  1 
ATOM   400  C  CG  . LYS A 1 54  ? 143.552 148.500 196.081 1.00 67.28  0  53  LYS A CG  1 
ATOM   401  C  CD  . LYS A 1 54  ? 143.112 147.286 196.882 1.00 67.28  0  53  LYS A CD  1 
ATOM   402  C  CE  . LYS A 1 54  ? 144.238 146.750 197.748 1.00 67.28  0  53  LYS A CE  1 
ATOM   403  N  NZ  . LYS A 1 54  ? 143.780 145.613 198.593 1.00 67.28  1  53  LYS A NZ  1 
ATOM   404  N  N   . MET A 1 55  ? 143.833 150.730 192.235 1.00 67.28  0  54  MET A N   1 
ATOM   405  C  CA  . MET A 1 55  ? 144.026 150.679 190.794 1.00 67.28  0  54  MET A CA  1 
ATOM   406  C  C   . MET A 1 55  ? 145.312 149.932 190.473 1.00 67.28  0  54  MET A C   1 
ATOM   407  O  O   . MET A 1 55  ? 146.366 150.217 191.053 1.00 67.28  0  54  MET A O   1 
ATOM   408  C  CB  . MET A 1 55  ? 144.059 152.083 190.190 1.00 67.28  0  54  MET A CB  1 
ATOM   409  C  CG  . MET A 1 55  ? 144.186 152.075 188.680 1.00 67.28  0  54  MET A CG  1 
ATOM   410  S  SD  . MET A 1 55  ? 144.105 153.739 187.995 1.00 67.28  0  54  MET A SD  1 
ATOM   411  C  CE  . MET A 1 55  ? 142.348 154.040 188.062 1.00 67.28  0  54  MET A CE  1 
ATOM   412  N  N   . THR A 1 56  ? 145.219 148.976 189.553 1.00 67.28  0  55  THR A N   1 
ATOM   413  C  CA  . THR A 1 56  ? 146.356 148.179 189.123 1.00 67.28  0  55  THR A CA  1 
ATOM   414  C  C   . THR A 1 56  ? 146.314 148.079 187.604 1.00 67.28  0  55  THR A C   1 
ATOM   415  O  O   . THR A 1 56  ? 145.493 148.718 186.938 1.00 67.28  0  55  THR A O   1 
ATOM   416  C  CB  . THR A 1 56  ? 146.341 146.799 189.792 1.00 67.28  0  55  THR A CB  1 
ATOM   417  O  OG1 . THR A 1 56  ? 147.555 146.106 189.482 1.00 67.28  0  55  THR A OG1 1 
ATOM   418  C  CG2 . THR A 1 56  ? 145.152 145.981 189.308 1.00 67.28  0  55  THR A CG2 1 
ATOM   419  N  N   . SER A 1 57  ? 147.198 147.259 187.043 1.00 67.28  0  56  SER A N   1 
ATOM   420  C  CA  . SER A 1 57  ? 147.311 147.174 185.597 1.00 67.28  0  56  SER A CA  1 
ATOM   421  C  C   . SER A 1 57  ? 147.614 145.745 185.179 1.00 67.28  0  56  SER A C   1 
ATOM   422  O  O   . SER A 1 57  ? 148.088 144.927 185.971 1.00 67.28  0  56  SER A O   1 
ATOM   423  C  CB  . SER A 1 57  ? 148.398 148.111 185.066 1.00 67.28  0  56  SER A CB  1 
ATOM   424  O  OG  . SER A 1 57  ? 149.659 147.465 185.065 1.00 67.28  0  56  SER A OG  1 
ATOM   425  N  N   . VAL A 1 58  ? 147.326 145.459 183.916 1.00 67.28  0  57  VAL A N   1 
ATOM   426  C  CA  . VAL A 1 58  ? 147.734 144.225 183.286 1.00 67.28  0  57  VAL A CA  1 
ATOM   427  C  C   . VAL A 1 58  ? 148.894 144.530 182.347 1.00 67.28  0  57  VAL A C   1 
ATOM   428  O  O   . VAL A 1 58  ? 149.263 145.682 182.134 1.00 67.28  0  57  VAL A O   1 
ATOM   429  C  CB  . VAL A 1 58  ? 146.564 143.543 182.536 1.00 67.28  0  57  VAL A CB  1 
ATOM   430  C  CG1 . VAL A 1 58  ? 145.396 143.305 183.476 1.00 67.28  0  57  VAL A CG1 1 
ATOM   431  C  CG2 . VAL A 1 58  ? 146.137 144.380 181.345 1.00 67.28  0  57  VAL A CG2 1 
ATOM   432  N  N   . CYS A 1 59  ? 149.499 143.485 181.795 1.00 69.33  0  58  CYS A N   1 
ATOM   433  C  CA  . CYS A 1 59  ? 150.589 143.628 180.833 1.00 69.33  0  58  CYS A CA  1 
ATOM   434  C  C   . CYS A 1 59  ? 150.067 143.166 179.475 1.00 69.33  0  58  CYS A C   1 
ATOM   435  O  O   . CYS A 1 59  ? 150.250 142.012 179.083 1.00 69.33  0  58  CYS A O   1 
ATOM   436  C  CB  . CYS A 1 59  ? 151.815 142.834 181.267 1.00 69.33  0  58  CYS A CB  1 
ATOM   437  S  SG  . CYS A 1 59  ? 152.589 143.430 182.787 1.00 69.33  0  58  CYS A SG  1 
ATOM   438  N  N   . GLY A 1 60  ? 149.428 144.083 178.753 1.00 68.07  0  59  GLY A N   1 
ATOM   439  C  CA  . GLY A 1 60  ? 148.848 143.731 177.469 1.00 68.07  0  59  GLY A CA  1 
ATOM   440  C  C   . GLY A 1 60  ? 147.773 142.676 177.622 1.00 68.07  0  59  GLY A C   1 
ATOM   441  O  O   . GLY A 1 60  ? 146.959 142.710 178.551 1.00 68.07  0  59  GLY A O   1 
ATOM   442  N  N   . HIS A 1 61  ? 147.765 141.722 176.695 1.00 70.64  0  60  HIS A N   1 
ATOM   443  C  CA  . HIS A 1 61  ? 146.838 140.603 176.787 1.00 70.64  0  60  HIS A CA  1 
ATOM   444  C  C   . HIS A 1 61  ? 147.166 139.742 178.000 1.00 70.64  0  60  HIS A C   1 
ATOM   445  O  O   . HIS A 1 61  ? 148.333 139.543 178.345 1.00 70.64  0  60  HIS A O   1 
ATOM   446  C  CB  . HIS A 1 61  ? 146.893 139.761 175.513 1.00 70.64  0  60  HIS A CB  1 
ATOM   447  C  CG  . HIS A 1 61  ? 145.875 140.152 174.488 1.00 70.64  0  60  HIS A CG  1 
ATOM   448  N  ND1 . HIS A 1 61  ? 144.590 139.655 174.489 1.00 70.64  0  60  HIS A ND1 1 
ATOM   449  C  CD2 . HIS A 1 61  ? 145.954 140.989 173.428 1.00 70.64  0  60  HIS A CD2 1 
ATOM   450  C  CE1 . HIS A 1 61  ? 143.920 140.171 173.474 1.00 70.64  0  60  HIS A CE1 1 
ATOM   451  N  NE2 . HIS A 1 61  ? 144.725 140.984 172.814 1.00 70.64  0  60  HIS A NE2 1 
ATOM   452  N  N   . VAL A 1 62  ? 146.123 139.232 178.649 1.00 70.59  0  61  VAL A N   1 
ATOM   453  C  CA  . VAL A 1 62  ? 146.290 138.409 179.838 1.00 70.59  0  61  VAL A CA  1 
ATOM   454  C  C   . VAL A 1 62  ? 146.075 136.924 179.561 1.00 70.59  0  61  VAL A C   1 
ATOM   455  O  O   . VAL A 1 62  ? 146.576 136.090 180.332 1.00 70.59  0  61  VAL A O   1 
ATOM   456  C  CB  . VAL A 1 62  ? 145.360 138.886 180.975 1.00 70.59  0  61  VAL A CB  1 
ATOM   457  C  CG1 . VAL A 1 62  ? 143.915 138.591 180.641 1.00 70.59  0  61  VAL A CG1 1 
ATOM   458  C  CG2 . VAL A 1 62  ? 145.754 138.267 182.309 1.00 70.59  0  61  VAL A CG2 1 
ATOM   459  N  N   . MET A 1 63  ? 145.376 136.562 178.486 1.00 73.67  0  62  MET A N   1 
ATOM   460  C  CA  . MET A 1 63  ? 145.152 135.165 178.142 1.00 73.67  0  62  MET A CA  1 
ATOM   461  C  C   . MET A 1 63  ? 145.282 135.003 176.634 1.00 73.67  0  62  MET A C   1 
ATOM   462  O  O   . MET A 1 63  ? 144.742 135.808 175.871 1.00 73.67  0  62  MET A O   1 
ATOM   463  C  CB  . MET A 1 63  ? 143.771 134.688 178.612 1.00 73.67  0  62  MET A CB  1 
ATOM   464  C  CG  . MET A 1 63  ? 143.579 134.737 180.124 1.00 73.67  0  62  MET A CG  1 
ATOM   465  S  SD  . MET A 1 63  ? 142.575 133.404 180.803 1.00 73.67  0  62  MET A SD  1 
ATOM   466  C  CE  . MET A 1 63  ? 143.838 132.195 181.182 1.00 73.67  0  62  MET A CE  1 
ATOM   467  N  N   . THR A 1 64  ? 145.999 133.964 176.207 1.00 72.90  0  63  THR A N   1 
ATOM   468  C  CA  . THR A 1 64  ? 146.233 133.700 174.793 1.00 72.90  0  63  THR A CA  1 
ATOM   469  C  C   . THR A 1 64  ? 145.726 132.312 174.424 1.00 72.90  0  63  THR A C   1 
ATOM   470  O  O   . THR A 1 64  ? 145.884 131.353 175.188 1.00 72.90  0  63  THR A O   1 
ATOM   471  C  CB  . THR A 1 64  ? 147.723 133.841 174.430 1.00 72.90  0  63  THR A CB  1 
ATOM   472  O  OG1 . THR A 1 64  ? 147.884 133.741 173.009 1.00 72.90  0  63  THR A OG1 1 
ATOM   473  C  CG2 . THR A 1 64  ? 148.569 132.774 175.115 1.00 72.90  0  63  THR A CG2 1 
ATOM   474  N  N   . LEU A 1 65  ? 145.113 132.216 173.246 1.00 69.56  0  64  LEU A N   1 
ATOM   475  C  CA  . LEU A 1 65  ? 144.441 130.997 172.817 1.00 69.56  0  64  LEU A CA  1 
ATOM   476  C  C   . LEU A 1 65  ? 145.436 130.005 172.227 1.00 69.56  0  64  LEU A C   1 
ATOM   477  O  O   . LEU A 1 65  ? 146.354 130.392 171.498 1.00 69.56  0  64  LEU A O   1 
ATOM   478  C  CB  . LEU A 1 65  ? 143.362 131.334 171.787 1.00 69.56  0  64  LEU A CB  1 
ATOM   479  C  CG  . LEU A 1 65  ? 142.225 130.338 171.545 1.00 69.56  0  64  LEU A CG  1 
ATOM   480  C  CD1 . LEU A 1 65  ? 141.715 129.759 172.849 1.00 69.56  0  64  LEU A CD1 1 
ATOM   481  C  CD2 . LEU A 1 65  ? 141.096 131.000 170.773 1.00 69.56  0  64  LEU A CD2 1 
ATOM   482  N  N   . ASP A 1 66  ? 145.241 128.726 172.537 1.00 69.72  0  65  ASP A N   1 
ATOM   483  C  CA  . ASP A 1 66  ? 146.006 127.627 171.958 1.00 69.72  0  65  ASP A CA  1 
ATOM   484  C  C   . ASP A 1 66  ? 145.175 126.356 172.092 1.00 69.72  0  65  ASP A C   1 
ATOM   485  O  O   . ASP A 1 66  ? 143.992 126.404 172.442 1.00 69.72  0  65  ASP A O   1 
ATOM   486  C  CB  . ASP A 1 66  ? 147.383 127.495 172.622 1.00 69.72  0  65  ASP A CB  1 
ATOM   487  C  CG  . ASP A 1 66  ? 148.464 128.258 171.880 1.00 69.72  0  65  ASP A CG  1 
ATOM   488  O  OD1 . ASP A 1 66  ? 148.270 128.554 170.682 1.00 69.72  0  65  ASP A OD1 1 
ATOM   489  O  OD2 . ASP A 1 66  ? 149.510 128.559 172.491 1.00 69.72  -1 65  ASP A OD2 1 
ATOM   490  N  N   . PHE A 1 67  ? 145.792 125.214 171.806 1.00 68.02  0  66  PHE A N   1 
ATOM   491  C  CA  . PHE A 1 67  ? 145.097 123.940 171.868 1.00 68.02  0  66  PHE A CA  1 
ATOM   492  C  C   . PHE A 1 67  ? 145.295 123.294 173.238 1.00 68.02  0  66  PHE A C   1 
ATOM   493  O  O   . PHE A 1 67  ? 145.897 123.869 174.147 1.00 68.02  0  66  PHE A O   1 
ATOM   494  C  CB  . PHE A 1 67  ? 145.566 123.028 170.736 1.00 68.02  0  66  PHE A CB  1 
ATOM   495  C  CG  . PHE A 1 67  ? 145.174 123.513 169.370 1.00 68.02  0  66  PHE A CG  1 
ATOM   496  C  CD1 . PHE A 1 67  ? 143.928 123.215 168.847 1.00 68.02  0  66  PHE A CD1 1 
ATOM   497  C  CD2 . PHE A 1 67  ? 146.048 124.270 168.612 1.00 68.02  0  66  PHE A CD2 1 
ATOM   498  C  CE1 . PHE A 1 67  ? 143.564 123.660 167.593 1.00 68.02  0  66  PHE A CE1 1 
ATOM   499  C  CE2 . PHE A 1 67  ? 145.689 124.717 167.357 1.00 68.02  0  66  PHE A CE2 1 
ATOM   500  C  CZ  . PHE A 1 67  ? 144.446 124.413 166.848 1.00 68.02  0  66  PHE A CZ  1 
ATOM   501  N  N   . LEU A 1 68  ? 144.777 122.077 173.390 1.00 71.20  0  67  LEU A N   1 
ATOM   502  C  CA  . LEU A 1 68  ? 144.777 121.382 174.671 1.00 71.20  0  67  LEU A CA  1 
ATOM   503  C  C   . LEU A 1 68  ? 146.121 120.721 174.983 1.00 71.20  0  67  LEU A C   1 
ATOM   504  O  O   . LEU A 1 68  ? 146.242 120.016 175.991 1.00 71.20  0  67  LEU A O   1 
ATOM   505  C  CB  . LEU A 1 68  ? 143.641 120.351 174.689 1.00 71.20  0  67  LEU A CB  1 
ATOM   506  C  CG  . LEU A 1 68  ? 143.277 119.589 175.968 1.00 71.20  0  67  LEU A CG  1 
ATOM   507  C  CD1 . LEU A 1 68  ? 142.792 120.551 177.040 1.00 71.20  0  67  LEU A CD1 1 
ATOM   508  C  CD2 . LEU A 1 68  ? 142.229 118.525 175.685 1.00 71.20  0  67  LEU A CD2 1 
ATOM   509  N  N   . GLY A 1 69  ? 147.141 120.957 174.162 1.00 76.63  0  68  GLY A N   1 
ATOM   510  C  CA  . GLY A 1 69  ? 148.445 120.364 174.388 1.00 76.63  0  68  GLY A CA  1 
ATOM   511  C  C   . GLY A 1 69  ? 148.652 119.071 173.628 1.00 76.63  0  68  GLY A C   1 
ATOM   512  O  O   . GLY A 1 69  ? 149.600 118.952 172.846 1.00 76.63  0  68  GLY A O   1 
ATOM   513  N  N   . LYS A 1 70  ? 147.768 118.094 173.847 1.00 78.68  0  69  LYS A N   1 
ATOM   514  C  CA  . LYS A 1 70  ? 147.864 116.836 173.114 1.00 78.68  0  69  LYS A CA  1 
ATOM   515  C  C   . LYS A 1 70  ? 147.730 117.053 171.614 1.00 78.68  0  69  LYS A C   1 
ATOM   516  O  O   . LYS A 1 70  ? 148.287 116.285 170.822 1.00 78.68  0  69  LYS A O   1 
ATOM   517  C  CB  . LYS A 1 70  ? 146.796 115.857 173.604 1.00 78.68  0  69  LYS A CB  1 
ATOM   518  C  CG  . LYS A 1 70  ? 146.811 115.617 175.104 1.00 78.68  0  69  LYS A CG  1 
ATOM   519  C  CD  . LYS A 1 70  ? 148.165 115.103 175.568 1.00 78.68  0  69  LYS A CD  1 
ATOM   520  C  CE  . LYS A 1 70  ? 148.368 113.650 175.166 1.00 78.68  0  69  LYS A CE  1 
ATOM   521  N  NZ  . LYS A 1 70  ? 149.542 113.039 175.850 1.00 78.68  1  69  LYS A NZ  1 
ATOM   522  N  N   . TYR A 1 71  ? 147.001 118.088 171.208 1.00 75.14  0  70  TYR A N   1 
ATOM   523  C  CA  . TYR A 1 71  ? 146.852 118.436 169.804 1.00 75.14  0  70  TYR A CA  1 
ATOM   524  C  C   . TYR A 1 71  ? 147.905 119.429 169.330 1.00 75.14  0  70  TYR A C   1 
ATOM   525  O  O   . TYR A 1 71  ? 147.932 119.760 168.141 1.00 75.14  0  70  TYR A O   1 
ATOM   526  C  CB  . TYR A 1 71  ? 145.455 119.011 169.554 1.00 75.14  0  70  TYR A CB  1 
ATOM   527  C  CG  . TYR A 1 71  ? 144.378 117.961 169.423 1.00 75.14  0  70  TYR A CG  1 
ATOM   528  C  CD1 . TYR A 1 71  ? 144.424 117.013 168.411 1.00 75.14  0  70  TYR A CD1 1 
ATOM   529  C  CD2 . TYR A 1 71  ? 143.316 117.917 170.315 1.00 75.14  0  70  TYR A CD2 1 
ATOM   530  C  CE1 . TYR A 1 71  ? 143.440 116.052 168.292 1.00 75.14  0  70  TYR A CE1 1 
ATOM   531  C  CE2 . TYR A 1 71  ? 142.328 116.959 170.203 1.00 75.14  0  70  TYR A CE2 1 
ATOM   532  C  CZ  . TYR A 1 71  ? 142.395 116.029 169.190 1.00 75.14  0  70  TYR A CZ  1 
ATOM   533  O  OH  . TYR A 1 71  ? 141.413 115.072 169.072 1.00 75.14  0  70  TYR A OH  1 
ATOM   534  N  N   . ASN A 1 72  ? 148.767 119.910 170.227 1.00 76.66  0  71  ASN A N   1 
ATOM   535  C  CA  . ASN A 1 72  ? 149.764 120.909 169.865 1.00 76.66  0  71  ASN A CA  1 
ATOM   536  C  C   . ASN A 1 72  ? 151.018 120.311 169.242 1.00 76.66  0  71  ASN A C   1 
ATOM   537  O  O   . ASN A 1 72  ? 151.826 121.061 168.684 1.00 76.66  0  71  ASN A O   1 
ATOM   538  C  CB  . ASN A 1 72  ? 150.151 121.735 171.095 1.00 76.66  0  71  ASN A CB  1 
ATOM   539  C  CG  . ASN A 1 72  ? 149.203 122.891 171.343 1.00 76.66  0  71  ASN A CG  1 
ATOM   540  O  OD1 . ASN A 1 72  ? 148.493 122.925 172.348 1.00 76.66  0  71  ASN A OD1 1 
ATOM   541  N  ND2 . ASN A 1 72  ? 149.186 123.849 170.423 1.00 76.66  0  71  ASN A ND2 1 
ATOM   542  N  N   . LYS A 1 73  ? 151.203 118.996 169.318 1.00 84.76  0  72  LYS A N   1 
ATOM   543  C  CA  . LYS A 1 73  ? 152.384 118.362 168.747 1.00 84.76  0  72  LYS A CA  1 
ATOM   544  C  C   . LYS A 1 73  ? 152.194 118.198 167.244 1.00 84.76  0  72  LYS A C   1 
ATOM   545  O  O   . LYS A 1 73  ? 151.315 117.450 166.801 1.00 84.76  0  72  LYS A O   1 
ATOM   546  C  CB  . LYS A 1 73  ? 152.641 117.012 169.412 1.00 84.76  0  72  LYS A CB  1 
ATOM   547  C  CG  . LYS A 1 73  ? 153.985 116.398 169.058 1.00 84.76  0  72  LYS A CG  1 
ATOM   548  C  CD  . LYS A 1 73  ? 155.120 117.367 169.347 1.00 84.76  0  72  LYS A CD  1 
ATOM   549  C  CE  . LYS A 1 73  ? 156.247 117.220 168.339 1.00 84.76  0  72  LYS A CE  1 
ATOM   550  N  NZ  . LYS A 1 73  ? 157.402 118.101 168.666 1.00 84.76  1  72  LYS A NZ  1 
ATOM   551  N  N   . TRP A 1 74  ? 153.018 118.896 166.460 1.00 87.11  0  73  TRP A N   1 
ATOM   552  C  CA  . TRP A 1 74  ? 152.874 118.864 165.009 1.00 87.11  0  73  TRP A CA  1 
ATOM   553  C  C   . TRP A 1 74  ? 153.348 117.550 164.401 1.00 87.11  0  73  TRP A C   1 
ATOM   554  O  O   . TRP A 1 74  ? 152.931 117.213 163.288 1.00 87.11  0  73  TRP A O   1 
ATOM   555  C  CB  . TRP A 1 74  ? 153.639 120.030 164.380 1.00 87.11  0  73  TRP A CB  1 
ATOM   556  C  CG  . TRP A 1 74  ? 155.117 119.977 164.621 1.00 87.11  0  73  TRP A CG  1 
ATOM   557  C  CD1 . TRP A 1 74  ? 156.058 119.400 163.819 1.00 87.11  0  73  TRP A CD1 1 
ATOM   558  C  CD2 . TRP A 1 74  ? 155.825 120.520 165.742 1.00 87.11  0  73  TRP A CD2 1 
ATOM   559  N  NE1 . TRP A 1 74  ? 157.308 119.551 164.370 1.00 87.11  0  73  TRP A NE1 1 
ATOM   560  C  CE2 . TRP A 1 74  ? 157.192 120.235 165.551 1.00 87.11  0  73  TRP A CE2 1 
ATOM   561  C  CE3 . TRP A 1 74  ? 155.436 121.221 166.888 1.00 87.11  0  73  TRP A CE3 1 
ATOM   562  C  CZ2 . TRP A 1 74  ? 158.170 120.626 166.462 1.00 87.11  0  73  TRP A CZ2 1 
ATOM   563  C  CZ3 . TRP A 1 74  ? 156.409 121.607 167.792 1.00 87.11  0  73  TRP A CZ3 1 
ATOM   564  C  CH2 . TRP A 1 74  ? 157.760 121.309 167.574 1.00 87.11  0  73  TRP A CH2 1 
ATOM   565  N  N   . ASP A 1 75  ? 154.208 116.804 165.099 1.00 88.13  0  74  ASP A N   1 
ATOM   566  C  CA  . ASP A 1 75  ? 154.748 115.575 164.527 1.00 88.13  0  74  ASP A CA  1 
ATOM   567  C  C   . ASP A 1 75  ? 153.699 114.470 164.478 1.00 88.13  0  74  ASP A C   1 
ATOM   568  O  O   . ASP A 1 75  ? 153.574 113.773 163.464 1.00 88.13  0  74  ASP A O   1 
ATOM   569  C  CB  . ASP A 1 75  ? 155.972 115.119 165.321 1.00 88.13  0  74  ASP A CB  1 
ATOM   570  C  CG  . ASP A 1 75  ? 157.208 115.938 165.007 1.00 88.13  0  74  ASP A CG  1 
ATOM   571  O  OD1 . ASP A 1 75  ? 157.313 116.443 163.870 1.00 88.13  0  74  ASP A OD1 1 
ATOM   572  O  OD2 . ASP A 1 75  ? 158.075 116.074 165.895 1.00 88.13  -1 74  ASP A OD2 1 
ATOM   573  N  N   . LYS A 1 76  ? 152.939 114.291 165.556 1.00 85.27  0  75  LYS A N   1 
ATOM   574  C  CA  . LYS A 1 76  ? 151.953 113.215 165.662 1.00 85.27  0  75  LYS A CA  1 
ATOM   575  C  C   . LYS A 1 76  ? 150.572 113.835 165.842 1.00 85.27  0  75  LYS A C   1 
ATOM   576  O  O   . LYS A 1 76  ? 150.084 113.988 166.964 1.00 85.27  0  75  LYS A O   1 
ATOM   577  C  CB  . LYS A 1 76  ? 152.309 112.275 166.820 1.00 85.27  0  75  LYS A CB  1 
ATOM   578  C  CG  . LYS A 1 76  ? 153.802 112.052 166.998 1.00 85.27  0  75  LYS A CG  1 
ATOM   579  C  CD  . LYS A 1 76  ? 154.084 110.833 167.859 1.00 85.27  0  75  LYS A CD  1 
ATOM   580  C  CE  . LYS A 1 76  ? 153.847 111.134 169.330 1.00 85.27  0  75  LYS A CE  1 
ATOM   581  N  NZ  . LYS A 1 76  ? 154.821 110.424 170.204 1.00 85.27  1  75  LYS A NZ  1 
ATOM   582  N  N   . VAL A 1 77  ? 149.938 114.182 164.721 1.00 78.33  0  76  VAL A N   1 
ATOM   583  C  CA  . VAL A 1 77  ? 148.585 114.727 164.715 1.00 78.33  0  76  VAL A CA  1 
ATOM   584  C  C   . VAL A 1 77  ? 148.062 114.702 163.284 1.00 78.33  0  76  VAL A C   1 
ATOM   585  O  O   . VAL A 1 77  ? 148.844 114.722 162.326 1.00 78.33  0  76  VAL A O   1 
ATOM   586  C  CB  . VAL A 1 77  ? 148.547 116.153 165.301 1.00 78.33  0  76  VAL A CB  1 
ATOM   587  C  CG1 . VAL A 1 77  ? 149.156 117.155 164.328 1.00 78.33  0  76  VAL A CG1 1 
ATOM   588  C  CG2 . VAL A 1 77  ? 147.123 116.547 165.679 1.00 78.33  0  76  VAL A CG2 1 
ATOM   589  N  N   . ASP A 1 78  ? 146.743 114.642 163.125 1.00 69.19  0  77  ASP A N   1 
ATOM   590  C  CA  . ASP A 1 78  ? 146.148 114.747 161.800 1.00 69.19  0  77  ASP A CA  1 
ATOM   591  C  C   . ASP A 1 78  ? 145.735 116.195 161.565 1.00 69.19  0  77  ASP A C   1 
ATOM   592  O  O   . ASP A 1 78  ? 144.688 116.634 162.064 1.00 69.19  0  77  ASP A O   1 
ATOM   593  C  CB  . ASP A 1 78  ? 144.948 113.808 161.664 1.00 69.19  0  77  ASP A CB  1 
ATOM   594  C  CG  . ASP A 1 78  ? 144.482 113.653 160.226 1.00 69.19  0  77  ASP A CG  1 
ATOM   595  O  OD1 . ASP A 1 78  ? 144.970 114.399 159.351 1.00 69.19  0  77  ASP A OD1 1 
ATOM   596  O  OD2 . ASP A 1 78  ? 143.625 112.782 159.971 1.00 69.19  -1 77  ASP A OD2 1 
ATOM   597  N  N   . PRO A 1 79  ? 146.499 116.957 160.771 1.00 67.28  0  78  PRO A N   1 
ATOM   598  C  CA  . PRO A 1 79  ? 146.248 118.401 160.689 1.00 67.28  0  78  PRO A CA  1 
ATOM   599  C  C   . PRO A 1 79  ? 145.034 118.719 159.836 1.00 67.28  0  78  PRO A C   1 
ATOM   600  O  O   . PRO A 1 79  ? 145.036 119.658 159.036 1.00 67.28  0  78  PRO A O   1 
ATOM   601  C  CB  . PRO A 1 79  ? 147.538 118.954 160.067 1.00 67.28  0  78  PRO A CB  1 
ATOM   602  C  CG  . PRO A 1 79  ? 148.283 117.762 159.508 1.00 67.28  0  78  PRO A CG  1 
ATOM   603  C  CD  . PRO A 1 79  ? 147.515 116.509 159.807 1.00 67.28  0  78  PRO A CD  1 
ATOM   604  N  N   . ALA A 1 80  ? 143.981 117.932 160.034 1.00 67.28  0  79  ALA A N   1 
ATOM   605  C  CA  . ALA A 1 80  ? 142.663 118.211 159.501 1.00 67.28  0  79  ALA A CA  1 
ATOM   606  C  C   . ALA A 1 80  ? 141.590 118.131 160.570 1.00 67.28  0  79  ALA A C   1 
ATOM   607  O  O   . ALA A 1 80  ? 140.447 118.519 160.302 1.00 67.28  0  79  ALA A O   1 
ATOM   608  C  CB  . ALA A 1 80  ? 142.315 117.239 158.363 1.00 67.28  0  79  ALA A CB  1 
ATOM   609  N  N   . GLU A 1 81  ? 141.919 117.647 161.767 1.00 68.25  0  80  GLU A N   1 
ATOM   610  C  CA  . GLU A 1 81  ? 140.979 117.593 162.875 1.00 68.25  0  80  GLU A CA  1 
ATOM   611  C  C   . GLU A 1 81  ? 141.152 118.758 163.840 1.00 68.25  0  80  GLU A C   1 
ATOM   612  O  O   . GLU A 1 81  ? 140.569 118.742 164.929 1.00 68.25  0  80  GLU A O   1 
ATOM   613  C  CB  . GLU A 1 81  ? 141.108 116.257 163.609 1.00 68.25  0  80  GLU A CB  1 
ATOM   614  C  CG  . GLU A 1 81  ? 142.453 116.015 164.268 1.00 68.25  0  80  GLU A CG  1 
ATOM   615  C  CD  . GLU A 1 81  ? 142.527 114.655 164.937 1.00 68.25  0  80  GLU A CD  1 
ATOM   616  O  OE1 . GLU A 1 81  ? 141.657 113.807 164.650 1.00 68.25  0  80  GLU A OE1 1 
ATOM   617  O  OE2 . GLU A 1 81  ? 143.464 114.425 165.729 1.00 68.25  -1 80  GLU A OE2 1 
ATOM   618  N  N   . LEU A 1 82  ? 141.943 119.763 163.467 1.00 67.28  0  81  LEU A N   1 
ATOM   619  C  CA  . LEU A 1 82  ? 142.027 121.001 164.229 1.00 67.28  0  81  LEU A CA  1 
ATOM   620  C  C   . LEU A 1 82  ? 140.892 121.963 163.910 1.00 67.28  0  81  LEU A C   1 
ATOM   621  O  O   . LEU A 1 82  ? 140.769 122.995 164.579 1.00 67.28  0  81  LEU A O   1 
ATOM   622  C  CB  . LEU A 1 82  ? 143.366 121.697 163.967 1.00 67.28  0  81  LEU A CB  1 
ATOM   623  C  CG  . LEU A 1 82  ? 144.657 120.937 164.276 1.00 67.28  0  81  LEU A CG  1 
ATOM   624  C  CD1 . LEU A 1 82  ? 145.830 121.899 164.337 1.00 67.28  0  81  LEU A CD1 1 
ATOM   625  C  CD2 . LEU A 1 82  ? 144.537 120.158 165.574 1.00 67.28  0  81  LEU A CD2 1 
ATOM   626  N  N   . PHE A 1 83  ? 140.065 121.654 162.910 1.00 67.28  0  82  PHE A N   1 
ATOM   627  C  CA  . PHE A 1 83  ? 139.002 122.565 162.502 1.00 67.28  0  82  PHE A CA  1 
ATOM   628  C  C   . PHE A 1 83  ? 137.825 122.521 163.470 1.00 67.28  0  82  PHE A C   1 
ATOM   629  O  O   . PHE A 1 83  ? 137.437 123.545 164.040 1.00 67.28  0  82  PHE A O   1 
ATOM   630  C  CB  . PHE A 1 83  ? 138.541 122.232 161.081 1.00 67.28  0  82  PHE A CB  1 
ATOM   631  C  CG  . PHE A 1 83  ? 139.454 122.753 160.008 1.00 67.28  0  82  PHE A CG  1 
ATOM   632  C  CD1 . PHE A 1 83  ? 139.418 124.085 159.638 1.00 67.28  0  82  PHE A CD1 1 
ATOM   633  C  CD2 . PHE A 1 83  ? 140.340 121.908 159.364 1.00 67.28  0  82  PHE A CD2 1 
ATOM   634  C  CE1 . PHE A 1 83  ? 140.253 124.566 158.651 1.00 67.28  0  82  PHE A CE1 1 
ATOM   635  C  CE2 . PHE A 1 83  ? 141.177 122.385 158.375 1.00 67.28  0  82  PHE A CE2 1 
ATOM   636  C  CZ  . PHE A 1 83  ? 141.133 123.715 158.019 1.00 67.28  0  82  PHE A CZ  1 
ATOM   637  N  N   . SER A 1 84  ? 137.241 121.337 163.670 1.00 67.28  0  83  SER A N   1 
ATOM   638  C  CA  . SER A 1 84  ? 136.053 121.222 164.507 1.00 67.28  0  83  SER A CA  1 
ATOM   639  C  C   . SER A 1 84  ? 136.115 120.005 165.420 1.00 67.28  0  83  SER A C   1 
ATOM   640  O  O   . SER A 1 84  ? 135.073 119.468 165.812 1.00 67.28  0  83  SER A O   1 
ATOM   641  C  CB  . SER A 1 84  ? 134.785 121.165 163.651 1.00 67.28  0  83  SER A CB  1 
ATOM   642  O  OG  . SER A 1 84  ? 134.621 119.883 163.070 1.00 67.28  0  83  SER A OG  1 
ATOM   643  N  N   . GLN A 1 85  ? 137.317 119.554 165.771 1.00 67.28  0  84  GLN A N   1 
ATOM   644  C  CA  . GLN A 1 85  ? 137.450 118.414 166.669 1.00 67.28  0  84  GLN A CA  1 
ATOM   645  C  C   . GLN A 1 85  ? 138.433 118.711 167.795 1.00 67.28  0  84  GLN A C   1 
ATOM   646  O  O   . GLN A 1 85  ? 138.334 118.135 168.883 1.00 67.28  0  84  GLN A O   1 
ATOM   647  C  CB  . GLN A 1 85  ? 137.886 117.172 165.889 1.00 67.28  0  84  GLN A CB  1 
ATOM   648  C  CG  . GLN A 1 85  ? 137.845 115.884 166.691 1.00 67.28  0  84  GLN A CG  1 
ATOM   649  C  CD  . GLN A 1 85  ? 137.896 114.652 165.812 1.00 67.28  0  84  GLN A CD  1 
ATOM   650  O  OE1 . GLN A 1 85  ? 137.066 114.477 164.920 1.00 67.28  0  84  GLN A OE1 1 
ATOM   651  N  NE2 . GLN A 1 85  ? 138.874 113.789 166.059 1.00 67.28  0  84  GLN A NE2 1 
ATOM   652  N  N   . ALA A 1 86  ? 139.377 119.616 167.550 1.00 67.28  0  85  ALA A N   1 
ATOM   653  C  CA  . ALA A 1 86  ? 140.395 119.943 168.539 1.00 67.28  0  85  ALA A CA  1 
ATOM   654  C  C   . ALA A 1 86  ? 139.885 121.036 169.467 1.00 67.28  0  85  ALA A C   1 
ATOM   655  O  O   . ALA A 1 86  ? 139.509 122.114 168.986 1.00 67.28  0  85  ALA A O   1 
ATOM   656  C  CB  . ALA A 1 86  ? 141.677 120.394 167.862 1.00 67.28  0  85  ALA A CB  1 
ATOM   657  N  N   . PRO A 1 87  ? 139.849 120.813 170.777 1.00 67.28  0  86  PRO A N   1 
ATOM   658  C  CA  . PRO A 1 87  ? 139.413 121.868 171.696 1.00 67.28  0  86  PRO A CA  1 
ATOM   659  C  C   . PRO A 1 87  ? 140.440 122.985 171.795 1.00 67.28  0  86  PRO A C   1 
ATOM   660  O  O   . PRO A 1 87  ? 141.625 122.812 171.501 1.00 67.28  0  86  PRO A O   1 
ATOM   661  C  CB  . PRO A 1 87  ? 139.259 121.134 173.031 1.00 67.28  0  86  PRO A CB  1 
ATOM   662  C  CG  . PRO A 1 87  ? 140.198 119.984 172.929 1.00 67.28  0  86  PRO A CG  1 
ATOM   663  C  CD  . PRO A 1 87  ? 140.200 119.570 171.484 1.00 67.28  0  86  PRO A CD  1 
ATOM   664  N  N   . THR A 1 88  ? 139.961 124.152 172.220 1.00 68.25  0  87  THR A N   1 
ATOM   665  C  CA  . THR A 1 88  ? 140.792 125.336 172.370 1.00 68.25  0  87  THR A CA  1 
ATOM   666  C  C   . THR A 1 88  ? 140.663 125.881 173.785 1.00 68.25  0  87  THR A C   1 
ATOM   667  O  O   . THR A 1 88  ? 139.611 125.766 174.419 1.00 68.25  0  87  THR A O   1 
ATOM   668  C  CB  . THR A 1 88  ? 140.411 126.427 171.360 1.00 68.25  0  87  THR A CB  1 
ATOM   669  O  OG1 . THR A 1 88  ? 138.985 126.564 171.316 1.00 68.25  0  87  THR A OG1 1 
ATOM   670  C  CG2 . THR A 1 88  ? 140.924 126.072 169.974 1.00 68.25  0  87  THR A CG2 1 
ATOM   671  N  N   . GLU A 1 89  ? 141.749 126.474 174.275 1.00 72.39  0  88  GLU A N   1 
ATOM   672  C  CA  . GLU A 1 89  ? 141.781 127.027 175.621 1.00 72.39  0  88  GLU A CA  1 
ATOM   673  C  C   . GLU A 1 89  ? 142.758 128.193 175.663 1.00 72.39  0  88  GLU A C   1 
ATOM   674  O  O   . GLU A 1 89  ? 143.785 128.187 174.979 1.00 72.39  0  88  GLU A O   1 
ATOM   675  C  CB  . GLU A 1 89  ? 142.177 125.964 176.653 1.00 72.39  0  88  GLU A CB  1 
ATOM   676  C  CG  . GLU A 1 89  ? 141.907 126.359 178.096 1.00 72.39  0  88  GLU A CG  1 
ATOM   677  C  CD  . GLU A 1 89  ? 142.173 125.227 179.069 1.00 72.39  0  88  GLU A CD  1 
ATOM   678  O  OE1 . GLU A 1 89  ? 142.629 124.153 178.623 1.00 72.39  0  88  GLU A OE1 1 
ATOM   679  O  OE2 . GLU A 1 89  ? 141.924 125.411 180.279 1.00 72.39  -1 88  GLU A OE2 1 
ATOM   680  N  N   . LYS A 1 90  ? 142.420 129.200 176.464 1.00 71.71  0  89  LYS A N   1 
ATOM   681  C  CA  . LYS A 1 90  ? 143.291 130.349 176.687 1.00 71.71  0  89  LYS A CA  1 
ATOM   682  C  C   . LYS A 1 90  ? 144.186 130.024 177.877 1.00 71.71  0  89  LYS A C   1 
ATOM   683  O  O   . LYS A 1 90  ? 143.706 129.922 179.010 1.00 71.71  0  89  LYS A O   1 
ATOM   684  C  CB  . LYS A 1 90  ? 142.461 131.607 176.930 1.00 71.71  0  89  LYS A CB  1 
ATOM   685  C  CG  . LYS A 1 90  ? 141.379 131.830 175.883 1.00 71.71  0  89  LYS A CG  1 
ATOM   686  C  CD  . LYS A 1 90  ? 140.696 133.177 176.047 1.00 71.71  0  89  LYS A CD  1 
ATOM   687  C  CE  . LYS A 1 90  ? 139.532 133.087 177.019 1.00 71.71  0  89  LYS A CE  1 
ATOM   688  N  NZ  . LYS A 1 90  ? 138.719 134.334 177.033 1.00 71.71  1  89  LYS A NZ  1 
ATOM   689  N  N   . LYS A 1 91  ? 145.483 129.840 177.624 1.00 75.59  0  90  LYS A N   1 
ATOM   690  C  CA  . LYS A 1 91  ? 146.337 129.182 178.621 1.00 75.59  0  90  LYS A CA  1 
ATOM   691  C  C   . LYS A 1 91  ? 146.866 130.123 179.704 1.00 75.59  0  90  LYS A C   1 
ATOM   692  O  O   . LYS A 1 91  ? 146.384 130.091 180.839 1.00 75.59  0  90  LYS A O   1 
ATOM   693  C  CB  . LYS A 1 91  ? 147.475 128.443 177.907 1.00 75.59  0  90  LYS A CB  1 
ATOM   694  C  CG  . LYS A 1 91  ? 148.273 129.266 176.902 1.00 75.59  0  90  LYS A CG  1 
ATOM   695  C  CD  . LYS A 1 91  ? 149.428 128.463 176.329 1.00 75.59  0  90  LYS A CD  1 
ATOM   696  C  CE  . LYS A 1 91  ? 150.333 129.331 175.470 1.00 75.59  0  90  LYS A CE  1 
ATOM   697  N  NZ  . LYS A 1 91  ? 151.480 128.559 174.916 1.00 75.59  1  90  LYS A NZ  1 
ATOM   698  N  N   . GLU A 1 92  ? 147.850 130.968 179.380 1.00 75.94  0  91  GLU A N   1 
ATOM   699  C  CA  . GLU A 1 92  ? 148.314 131.900 180.404 1.00 75.94  0  91  GLU A CA  1 
ATOM   700  C  C   . GLU A 1 92  ? 148.775 133.262 179.892 1.00 75.94  0  91  GLU A C   1 
ATOM   701  O  O   . GLU A 1 92  ? 148.710 134.247 180.635 1.00 75.94  0  91  GLU A O   1 
ATOM   702  C  CB  . GLU A 1 92  ? 149.433 131.256 181.222 1.00 75.94  0  91  GLU A CB  1 
ATOM   703  C  CG  . GLU A 1 92  ? 149.541 131.809 182.634 1.00 75.94  0  91  GLU A CG  1 
ATOM   704  C  CD  . GLU A 1 92  ? 148.205 131.877 183.346 1.00 75.94  0  91  GLU A CD  1 
ATOM   705  O  OE1 . GLU A 1 92  ? 147.474 130.864 183.349 1.00 75.94  0  91  GLU A OE1 1 
ATOM   706  O  OE2 . GLU A 1 92  ? 147.883 132.948 183.903 1.00 75.94  -1 91  GLU A OE2 1 
ATOM   707  N  N   . ALA A 1 93  ? 149.248 133.337 178.643 1.00 75.30  0  92  ALA A N   1 
ATOM   708  C  CA  . ALA A 1 93  ? 149.768 134.583 178.070 1.00 75.30  0  92  ALA A CA  1 
ATOM   709  C  C   . ALA A 1 93  ? 150.923 135.142 178.911 1.00 75.30  0  92  ALA A C   1 
ATOM   710  O  O   . ALA A 1 93  ? 150.775 136.109 179.662 1.00 75.30  0  92  ALA A O   1 
ATOM   711  C  CB  . ALA A 1 93  ? 148.660 135.625 177.890 1.00 75.30  0  92  ALA A CB  1 
ATOM   712  N  N   . ASN A 1 94  ? 152.082 134.475 178.780 1.00 78.32  0  93  ASN A N   1 
ATOM   713  C  CA  . ASN A 1 94  ? 153.315 134.768 179.515 1.00 78.32  0  93  ASN A CA  1 
ATOM   714  C  C   . ASN A 1 94  ? 153.178 134.433 180.997 1.00 78.32  0  93  ASN A C   1 
ATOM   715  O  O   . ASN A 1 94  ? 153.130 135.332 181.851 1.00 78.32  0  93  ASN A O   1 
ATOM   716  C  CB  . ASN A 1 94  ? 153.718 136.236 179.331 1.00 78.32  0  93  ASN A CB  1 
ATOM   717  C  CG  . ASN A 1 94  ? 155.095 136.548 179.894 1.00 78.32  0  93  ASN A CG  1 
ATOM   718  O  OD1 . ASN A 1 94  ? 155.765 135.681 180.455 1.00 78.32  0  93  ASN A OD1 1 
ATOM   719  N  ND2 . ASN A 1 94  ? 155.521 137.797 179.746 1.00 78.32  0  93  ASN A ND2 1 
ATOM   720  N  N   . PRO A 1 95  ? 153.134 133.138 181.333 1.00 78.17  0  94  PRO A N   1 
ATOM   721  C  CA  . PRO A 1 95  ? 152.947 132.730 182.736 1.00 78.17  0  94  PRO A CA  1 
ATOM   722  C  C   . PRO A 1 95  ? 153.983 133.288 183.695 1.00 78.17  0  94  PRO A C   1 
ATOM   723  O  O   . PRO A 1 95  ? 153.773 133.205 184.912 1.00 78.17  0  94  PRO A O   1 
ATOM   724  C  CB  . PRO A 1 95  ? 153.037 131.196 182.676 1.00 78.17  0  94  PRO A CB  1 
ATOM   725  C  CG  . PRO A 1 95  ? 152.921 130.837 181.226 1.00 78.17  0  94  PRO A CG  1 
ATOM   726  C  CD  . PRO A 1 95  ? 153.452 131.998 180.460 1.00 78.17  0  94  PRO A CD  1 
ATOM   727  N  N   . LYS A 1 96  ? 155.090 133.841 183.196 1.00 79.47  0  95  LYS A N   1 
ATOM   728  C  CA  . LYS A 1 96  ? 156.078 134.444 184.080 1.00 79.47  0  95  LYS A CA  1 
ATOM   729  C  C   . LYS A 1 96  ? 155.506 135.633 184.841 1.00 79.47  0  95  LYS A C   1 
ATOM   730  O  O   . LYS A 1 96  ? 156.066 136.025 185.871 1.00 79.47  0  95  LYS A O   1 
ATOM   731  C  CB  . LYS A 1 96  ? 157.310 134.862 183.269 1.00 79.47  0  95  LYS A CB  1 
ATOM   732  C  CG  . LYS A 1 96  ? 158.480 135.374 184.096 1.00 79.47  0  95  LYS A CG  1 
ATOM   733  C  CD  . LYS A 1 96  ? 159.706 135.620 183.230 1.00 79.47  0  95  LYS A CD  1 
ATOM   734  C  CE  . LYS A 1 96  ? 159.534 136.857 182.365 1.00 79.47  0  95  LYS A CE  1 
ATOM   735  N  NZ  . LYS A 1 96  ? 160.769 137.168 181.594 1.00 79.47  1  95  LYS A NZ  1 
ATOM   736  N  N   . LEU A 1 97  ? 154.390 136.201 184.377 1.00 76.54  0  96  LEU A N   1 
ATOM   737  C  CA  . LEU A 1 97  ? 153.788 137.339 185.059 1.00 76.54  0  96  LEU A CA  1 
ATOM   738  C  C   . LEU A 1 97  ? 152.787 136.947 186.138 1.00 76.54  0  96  LEU A C   1 
ATOM   739  O  O   . LEU A 1 97  ? 152.562 137.739 187.060 1.00 76.54  0  96  LEU A O   1 
ATOM   740  C  CB  . LEU A 1 97  ? 153.102 138.262 184.046 1.00 76.54  0  96  LEU A CB  1 
ATOM   741  C  CG  . LEU A 1 97  ? 154.027 139.260 183.348 1.00 76.54  0  96  LEU A CG  1 
ATOM   742  C  CD1 . LEU A 1 97  ? 153.459 139.671 182.001 1.00 76.54  0  96  LEU A CD1 1 
ATOM   743  C  CD2 . LEU A 1 97  ? 154.267 140.477 184.229 1.00 76.54  0  96  LEU A CD2 1 
ATOM   744  N  N   . ASN A 1 98  ? 152.191 135.755 186.053 1.00 75.51  0  97  ASN A N   1 
ATOM   745  C  CA  . ASN A 1 98  ? 151.216 135.281 187.041 1.00 75.51  0  97  ASN A CA  1 
ATOM   746  C  C   . ASN A 1 98  ? 150.081 136.286 187.224 1.00 75.51  0  97  ASN A C   1 
ATOM   747  O  O   . ASN A 1 98  ? 149.653 136.583 188.344 1.00 75.51  0  97  ASN A O   1 
ATOM   748  C  CB  . ASN A 1 98  ? 151.892 134.972 188.378 1.00 75.51  0  97  ASN A CB  1 
ATOM   749  C  CG  . ASN A 1 98  ? 152.895 133.842 188.276 1.00 75.51  0  97  ASN A CG  1 
ATOM   750  O  OD1 . ASN A 1 98  ? 154.096 134.043 188.457 1.00 75.51  0  97  ASN A OD1 1 
ATOM   751  N  ND2 . ASN A 1 98  ? 152.407 132.642 187.985 1.00 75.51  0  97  ASN A ND2 1 
ATOM   752  N  N   . MET A 1 99  ? 149.585 136.812 186.103 1.00 72.99  0  98  MET A N   1 
ATOM   753  C  CA  . MET A 1 99  ? 148.619 137.904 186.161 1.00 72.99  0  98  MET A CA  1 
ATOM   754  C  C   . MET A 1 99  ? 147.288 137.452 186.746 1.00 72.99  0  98  MET A C   1 
ATOM   755  O  O   . MET A 1 99  ? 146.622 138.225 187.442 1.00 72.99  0  98  MET A O   1 
ATOM   756  C  CB  . MET A 1 99  ? 148.417 138.505 184.771 1.00 72.99  0  98  MET A CB  1 
ATOM   757  C  CG  . MET A 1 99  ? 149.524 139.452 184.343 1.00 72.99  0  98  MET A CG  1 
ATOM   758  S  SD  . MET A 1 99  ? 149.449 141.053 185.172 1.00 72.99  0  98  MET A SD  1 
ATOM   759  C  CE  . MET A 1 99  ? 147.684 141.254 185.397 1.00 72.99  0  98  MET A CE  1 
ATOM   760  N  N   . VAL A 1 100 ? 146.875 136.212 186.475 1.00 71.24  0  99  VAL A N   1 
ATOM   761  C  CA  . VAL A 1 100 ? 145.601 135.728 187.003 1.00 71.24  0  99  VAL A CA  1 
ATOM   762  C  C   . VAL A 1 100 ? 145.643 135.675 188.526 1.00 71.24  0  99  VAL A C   1 
ATOM   763  O  O   . VAL A 1 100 ? 144.734 136.162 189.211 1.00 71.24  0  99  VAL A O   1 
ATOM   764  C  CB  . VAL A 1 100 ? 145.254 134.356 186.398 1.00 71.24  0  99  VAL A CB  1 
ATOM   765  C  CG1 . VAL A 1 100 ? 143.970 133.819 187.006 1.00 71.24  0  99  VAL A CG1 1 
ATOM   766  C  CG2 . VAL A 1 100 ? 145.128 134.463 184.888 1.00 71.24  0  99  VAL A CG2 1 
ATOM   767  N  N   . LYS A 1 101 ? 146.710 135.092 189.078 1.00 72.02  0  100 LYS A N   1 
ATOM   768  C  CA  . LYS A 1 101 ? 146.849 135.029 190.529 1.00 72.02  0  100 LYS A CA  1 
ATOM   769  C  C   . LYS A 1 101 ? 147.004 136.420 191.129 1.00 72.02  0  100 LYS A C   1 
ATOM   770  O  O   . LYS A 1 101 ? 146.470 136.698 192.210 1.00 72.02  0  100 LYS A O   1 
ATOM   771  C  CB  . LYS A 1 101 ? 148.037 134.146 190.908 1.00 72.02  0  100 LYS A CB  1 
ATOM   772  C  CG  . LYS A 1 101 ? 147.907 133.493 192.275 1.00 72.02  0  100 LYS A CG  1 
ATOM   773  C  CD  . LYS A 1 101 ? 148.821 132.287 192.405 1.00 72.02  0  100 LYS A CD  1 
ATOM   774  C  CE  . LYS A 1 101 ? 150.228 132.702 192.804 1.00 72.02  0  100 LYS A CE  1 
ATOM   775  N  NZ  . LYS A 1 101 ? 150.295 133.136 194.227 1.00 72.02  1  100 LYS A NZ  1 
ATOM   776  N  N   . PHE A 1 102 ? 147.737 137.305 190.447 1.00 70.40  0  101 PHE A N   1 
ATOM   777  C  CA  . PHE A 1 102 ? 147.896 138.668 190.942 1.00 70.40  0  101 PHE A CA  1 
ATOM   778  C  C   . PHE A 1 102 ? 146.552 139.384 191.013 1.00 70.40  0  101 PHE A C   1 
ATOM   779  O  O   . PHE A 1 102 ? 146.237 140.046 192.008 1.00 70.40  0  101 PHE A O   1 
ATOM   780  C  CB  . PHE A 1 102 ? 148.874 139.435 190.052 1.00 70.40  0  101 PHE A CB  1 
ATOM   781  C  CG  . PHE A 1 102 ? 148.881 140.916 190.294 1.00 70.40  0  101 PHE A CG  1 
ATOM   782  C  CD1 . PHE A 1 102 ? 149.083 141.422 191.567 1.00 70.40  0  101 PHE A CD1 1 
ATOM   783  C  CD2 . PHE A 1 102 ? 148.691 141.802 189.249 1.00 70.40  0  101 PHE A CD2 1 
ATOM   784  C  CE1 . PHE A 1 102 ? 149.091 142.781 191.793 1.00 70.40  0  101 PHE A CE1 1 
ATOM   785  C  CE2 . PHE A 1 102 ? 148.698 143.163 189.469 1.00 70.40  0  101 PHE A CE2 1 
ATOM   786  C  CZ  . PHE A 1 102 ? 148.899 143.653 190.744 1.00 70.40  0  101 PHE A CZ  1 
ATOM   787  N  N   . LEU A 1 103 ? 145.737 139.249 189.965 1.00 69.09  0  102 LEU A N   1 
ATOM   788  C  CA  . LEU A 1 103 ? 144.420 139.874 189.963 1.00 69.09  0  102 LEU A CA  1 
ATOM   789  C  C   . LEU A 1 103 ? 143.528 139.278 191.041 1.00 69.09  0  102 LEU A C   1 
ATOM   790  O  O   . LEU A 1 103 ? 142.776 140.003 191.703 1.00 69.09  0  102 LEU A O   1 
ATOM   791  C  CB  . LEU A 1 103 ? 143.771 139.729 188.587 1.00 69.09  0  102 LEU A CB  1 
ATOM   792  C  CG  . LEU A 1 103 ? 144.116 140.808 187.559 1.00 69.09  0  102 LEU A CG  1 
ATOM   793  C  CD1 . LEU A 1 103 ? 143.622 140.408 186.180 1.00 69.09  0  102 LEU A CD1 1 
ATOM   794  C  CD2 . LEU A 1 103 ? 143.531 142.147 187.973 1.00 69.09  0  102 LEU A CD2 1 
ATOM   795  N  N   . GLN A 1 104 ? 143.596 137.959 191.235 1.00 70.27  0  103 GLN A N   1 
ATOM   796  C  CA  . GLN A 1 104 ? 142.769 137.325 192.258 1.00 70.27  0  103 GLN A CA  1 
ATOM   797  C  C   . GLN A 1 104 ? 143.146 137.812 193.653 1.00 70.27  0  103 GLN A C   1 
ATOM   798  O  O   . GLN A 1 104 ? 142.273 138.146 194.463 1.00 70.27  0  103 GLN A O   1 
ATOM   799  C  CB  . GLN A 1 104 ? 142.888 135.804 192.161 1.00 70.27  0  103 GLN A CB  1 
ATOM   800  C  CG  . GLN A 1 104 ? 141.986 135.185 191.105 1.00 70.27  0  103 GLN A CG  1 
ATOM   801  C  CD  . GLN A 1 104 ? 142.152 133.683 191.001 1.00 70.27  0  103 GLN A CD  1 
ATOM   802  O  OE1 . GLN A 1 104 ? 143.038 133.099 191.625 1.00 70.27  0  103 GLN A OE1 1 
ATOM   803  N  NE2 . GLN A 1 104 ? 141.295 133.048 190.211 1.00 70.27  0  103 GLN A NE2 1 
ATOM   804  N  N   . VAL A 1 105 ? 144.447 137.872 193.951 1.00 69.66  0  104 VAL A N   1 
ATOM   805  C  CA  . VAL A 1 105 ? 144.860 138.313 195.281 1.00 69.66  0  104 VAL A CA  1 
ATOM   806  C  C   . VAL A 1 105 ? 144.591 139.802 195.465 1.00 69.66  0  104 VAL A C   1 
ATOM   807  O  O   . VAL A 1 105 ? 144.322 140.256 196.584 1.00 69.66  0  104 VAL A O   1 
ATOM   808  C  CB  . VAL A 1 105 ? 146.338 137.957 195.545 1.00 69.66  0  104 VAL A CB  1 
ATOM   809  C  CG1 . VAL A 1 105 ? 147.261 138.715 194.612 1.00 69.66  0  104 VAL A CG1 1 
ATOM   810  C  CG2 . VAL A 1 105 ? 146.703 138.219 197.001 1.00 69.66  0  104 VAL A CG2 1 
ATOM   811  N  N   . GLU A 1 106 ? 144.643 140.587 194.384 1.00 70.08  0  105 GLU A N   1 
ATOM   812  C  CA  . GLU A 1 106 ? 144.335 142.009 194.496 1.00 70.08  0  105 GLU A CA  1 
ATOM   813  C  C   . GLU A 1 106 ? 142.849 142.237 194.741 1.00 70.08  0  105 GLU A C   1 
ATOM   814  O  O   . GLU A 1 106 ? 142.471 143.103 195.538 1.00 70.08  0  105 GLU A O   1 
ATOM   815  C  CB  . GLU A 1 106 ? 144.792 142.744 193.237 1.00 70.08  0  105 GLU A CB  1 
ATOM   816  C  CG  . GLU A 1 106 ? 144.631 144.253 193.300 1.00 70.08  0  105 GLU A CG  1 
ATOM   817  C  CD  . GLU A 1 106 ? 145.566 144.901 194.303 1.00 70.08  0  105 GLU A CD  1 
ATOM   818  O  OE1 . GLU A 1 106 ? 146.585 144.276 194.664 1.00 70.08  0  105 GLU A OE1 1 
ATOM   819  O  OE2 . GLU A 1 106 ? 145.283 146.041 194.728 1.00 70.08  -1 105 GLU A OE2 1 
ATOM   820  N  N   . GLY A 1 107 ? 141.993 141.474 194.067 1.00 69.10  0  106 GLY A N   1 
ATOM   821  C  CA  . GLY A 1 107 ? 140.561 141.614 194.228 1.00 69.10  0  106 GLY A CA  1 
ATOM   822  C  C   . GLY A 1 107 ? 139.974 140.637 195.224 1.00 69.10  0  106 GLY A C   1 
ATOM   823  O  O   . GLY A 1 107 ? 138.768 140.372 195.200 1.00 69.10  0  106 GLY A O   1 
ATOM   824  N  N   . ARG A 1 108 ? 140.827 140.079 196.089 1.00 70.52  0  107 ARG A N   1 
ATOM   825  C  CA  . ARG A 1 108 ? 140.360 139.156 197.120 1.00 70.52  0  107 ARG A CA  1 
ATOM   826  C  C   . ARG A 1 108 ? 139.214 139.753 197.927 1.00 70.52  0  107 ARG A C   1 
ATOM   827  O  O   . ARG A 1 108 ? 138.259 139.052 198.280 1.00 70.52  0  107 ARG A O   1 
ATOM   828  C  CB  . ARG A 1 108 ? 141.519 138.770 198.040 1.00 70.52  0  107 ARG A CB  1 
ATOM   829  C  CG  . ARG A 1 108 ? 141.165 137.716 199.073 1.00 70.52  0  107 ARG A CG  1 
ATOM   830  C  CD  . ARG A 1 108 ? 140.916 136.372 198.409 1.00 70.52  0  107 ARG A CD  1 
ATOM   831  N  NE  . ARG A 1 108 ? 139.504 136.008 198.420 1.00 70.52  0  107 ARG A NE  1 
ATOM   832  C  CZ  . ARG A 1 108 ? 139.015 134.891 197.899 1.00 70.52  0  107 ARG A CZ  1 
ATOM   833  N  NH1 . ARG A 1 108 ? 139.798 134.000 197.314 1.00 70.52  1  107 ARG A NH1 1 
ATOM   834  N  NH2 . ARG A 1 108 ? 137.706 134.663 197.966 1.00 70.52  0  107 ARG A NH2 1 
ATOM   835  N  N   . GLY A 1 109 ? 139.295 141.044 198.238 1.00 69.29  0  108 GLY A N   1 
ATOM   836  C  CA  . GLY A 1 109 ? 138.163 141.742 198.814 1.00 69.29  0  108 GLY A CA  1 
ATOM   837  C  C   . GLY A 1 109 ? 137.815 142.989 198.031 1.00 69.29  0  108 GLY A C   1 
ATOM   838  O  O   . GLY A 1 109 ? 138.577 143.961 198.034 1.00 69.29  0  108 GLY A O   1 
ATOM   839  N  N   . CYS A 1 110 ? 136.659 142.983 197.372 1.00 69.23  0  109 CYS A N   1 
ATOM   840  C  CA  . CYS A 1 110 ? 136.249 144.097 196.530 1.00 69.23  0  109 CYS A CA  1 
ATOM   841  C  C   . CYS A 1 110 ? 134.738 144.068 196.367 1.00 69.23  0  109 CYS A C   1 
ATOM   842  O  O   . CYS A 1 110 ? 134.102 143.026 196.541 1.00 69.23  0  109 CYS A O   1 
ATOM   843  C  CB  . CYS A 1 110 ? 136.929 144.048 195.157 1.00 69.23  0  109 CYS A CB  1 
ATOM   844  S  SG  . CYS A 1 110 ? 138.562 144.815 195.085 1.00 69.23  0  109 CYS A SG  1 
ATOM   845  N  N   . ASP A 1 111 ? 134.173 145.228 196.027 1.00 67.28  0  110 ASP A N   1 
ATOM   846  C  CA  . ASP A 1 111 ? 132.745 145.353 195.778 1.00 67.28  0  110 ASP A CA  1 
ATOM   847  C  C   . ASP A 1 111 ? 132.403 146.004 194.447 1.00 67.28  0  110 ASP A C   1 
ATOM   848  O  O   . ASP A 1 111 ? 131.307 145.762 193.931 1.00 67.28  0  110 ASP A O   1 
ATOM   849  C  CB  . ASP A 1 111 ? 132.069 146.149 196.904 1.00 67.28  0  110 ASP A CB  1 
ATOM   850  C  CG  . ASP A 1 111 ? 132.525 145.710 198.280 1.00 67.28  0  110 ASP A CG  1 
ATOM   851  O  OD1 . ASP A 1 111 ? 132.616 144.489 198.517 1.00 67.28  0  110 ASP A OD1 1 
ATOM   852  O  OD2 . ASP A 1 111 ? 132.797 146.585 199.126 1.00 67.28  -1 110 ASP A OD2 1 
ATOM   853  N  N   . TYR A 1 112 ? 133.293 146.817 193.883 1.00 67.28  0  111 TYR A N   1 
ATOM   854  C  CA  . TYR A 1 112 ? 133.087 147.401 192.568 1.00 67.28  0  111 TYR A CA  1 
ATOM   855  C  C   . TYR A 1 112 ? 134.354 147.240 191.745 1.00 67.28  0  111 TYR A C   1 
ATOM   856  O  O   . TYR A 1 112 ? 135.465 147.227 192.282 1.00 67.28  0  111 TYR A O   1 
ATOM   857  C  CB  . TYR A 1 112 ? 132.717 148.890 192.637 1.00 67.28  0  111 TYR A CB  1 
ATOM   858  C  CG  . TYR A 1 112 ? 131.545 149.219 193.532 1.00 67.28  0  111 TYR A CG  1 
ATOM   859  C  CD1 . TYR A 1 112 ? 131.709 149.367 194.901 1.00 67.28  0  111 TYR A CD1 1 
ATOM   860  C  CD2 . TYR A 1 112 ? 130.274 149.396 193.003 1.00 67.28  0  111 TYR A CD2 1 
ATOM   861  C  CE1 . TYR A 1 112 ? 130.642 149.674 195.718 1.00 67.28  0  111 TYR A CE1 1 
ATOM   862  C  CE2 . TYR A 1 112 ? 129.199 149.702 193.814 1.00 67.28  0  111 TYR A CE2 1 
ATOM   863  C  CZ  . TYR A 1 112 ? 129.389 149.840 195.171 1.00 67.28  0  111 TYR A CZ  1 
ATOM   864  O  OH  . TYR A 1 112 ? 128.322 150.145 195.984 1.00 67.28  0  111 TYR A OH  1 
ATOM   865  N  N   . ILE A 1 113 ? 134.177 147.113 190.434 1.00 67.28  0  112 ILE A N   1 
ATOM   866  C  CA  . ILE A 1 113 ? 135.285 147.094 189.488 1.00 67.28  0  112 ILE A CA  1 
ATOM   867  C  C   . ILE A 1 113 ? 134.980 148.069 188.359 1.00 67.28  0  112 ILE A C   1 
ATOM   868  O  O   . ILE A 1 113 ? 133.850 148.119 187.860 1.00 67.28  0  112 ILE A O   1 
ATOM   869  C  CB  . ILE A 1 113 ? 135.560 145.678 188.940 1.00 67.28  0  112 ILE A CB  1 
ATOM   870  C  CG1 . ILE A 1 113 ? 136.875 145.666 188.156 1.00 67.28  0  112 ILE A CG1 1 
ATOM   871  C  CG2 . ILE A 1 113 ? 134.396 145.157 188.104 1.00 67.28  0  112 ILE A CG2 1 
ATOM   872  C  CD1 . ILE A 1 113 ? 137.395 144.289 187.851 1.00 67.28  0  112 ILE A CD1 1 
ATOM   873  N  N   . VAL A 1 114 ? 135.974 148.872 187.992 1.00 67.28  0  113 VAL A N   1 
ATOM   874  C  CA  . VAL A 1 114 ? 135.919 149.707 186.799 1.00 67.28  0  113 VAL A CA  1 
ATOM   875  C  C   . VAL A 1 114 ? 137.153 149.382 185.969 1.00 67.28  0  113 VAL A C   1 
ATOM   876  O  O   . VAL A 1 114 ? 138.254 149.243 186.513 1.00 67.28  0  113 VAL A O   1 
ATOM   877  C  CB  . VAL A 1 114 ? 135.845 151.212 187.137 1.00 67.28  0  113 VAL A CB  1 
ATOM   878  C  CG1 . VAL A 1 114 ? 137.098 151.657 187.871 1.00 67.28  0  113 VAL A CG1 1 
ATOM   879  C  CG2 . VAL A 1 114 ? 135.657 152.047 185.900 1.00 67.28  0  113 VAL A CG2 1 
ATOM   880  N  N   . LEU A 1 115 ? 136.966 149.204 184.668 1.00 67.28  0  114 LEU A N   1 
ATOM   881  C  CA  . LEU A 1 115 ? 138.041 148.756 183.791 1.00 67.28  0  114 LEU A CA  1 
ATOM   882  C  C   . LEU A 1 115 ? 138.448 149.904 182.877 1.00 67.28  0  114 LEU A C   1 
ATOM   883  O  O   . LEU A 1 115 ? 137.635 150.396 182.087 1.00 67.28  0  114 LEU A O   1 
ATOM   884  C  CB  . LEU A 1 115 ? 137.617 147.523 182.997 1.00 67.28  0  114 LEU A CB  1 
ATOM   885  C  CG  . LEU A 1 115 ? 137.363 146.300 183.884 1.00 67.28  0  114 LEU A CG  1 
ATOM   886  C  CD1 . LEU A 1 115 ? 135.874 146.083 184.102 1.00 67.28  0  114 LEU A CD1 1 
ATOM   887  C  CD2 . LEU A 1 115 ? 138.035 145.047 183.337 1.00 67.28  0  114 LEU A CD2 1 
ATOM   888  N  N   . TRP A 1 116 ? 139.708 150.326 182.990 1.00 67.28  0  115 TRP A N   1 
ATOM   889  C  CA  . TRP A 1 116 ? 140.271 151.394 182.176 1.00 67.28  0  115 TRP A CA  1 
ATOM   890  C  C   . TRP A 1 116 ? 141.070 150.859 180.994 1.00 67.28  0  115 TRP A C   1 
ATOM   891  O  O   . TRP A 1 116 ? 142.061 151.473 180.582 1.00 67.28  0  115 TRP A O   1 
ATOM   892  C  CB  . TRP A 1 116 ? 141.140 152.312 183.034 1.00 67.28  0  115 TRP A CB  1 
ATOM   893  C  CG  . TRP A 1 116 ? 140.364 153.073 184.051 1.00 67.28  0  115 TRP A CG  1 
ATOM   894  C  CD1 . TRP A 1 116 ? 140.046 152.675 185.314 1.00 67.28  0  115 TRP A CD1 1 
ATOM   895  C  CD2 . TRP A 1 116 ? 139.807 154.381 183.889 1.00 67.28  0  115 TRP A CD2 1 
ATOM   896  N  NE1 . TRP A 1 116 ? 139.321 153.653 185.949 1.00 67.28  0  115 TRP A NE1 1 
ATOM   897  C  CE2 . TRP A 1 116 ? 139.160 154.713 185.094 1.00 67.28  0  115 TRP A CE2 1 
ATOM   898  C  CE3 . TRP A 1 116 ? 139.792 155.301 182.839 1.00 67.28  0  115 TRP A CE3 1 
ATOM   899  C  CZ2 . TRP A 1 116 ? 138.506 155.926 185.275 1.00 67.28  0  115 TRP A CZ2 1 
ATOM   900  C  CZ3 . TRP A 1 116 ? 139.143 156.503 183.021 1.00 67.28  0  115 TRP A CZ3 1 
ATOM   901  C  CH2 . TRP A 1 116 ? 138.508 156.807 184.231 1.00 67.28  0  115 TRP A CH2 1 
ATOM   902  N  N   . LEU A 1 117 ? 140.656 149.725 180.438 1.00 67.28  0  116 LEU A N   1 
ATOM   903  C  CA  . LEU A 1 117 ? 141.322 149.169 179.275 1.00 67.28  0  116 LEU A CA  1 
ATOM   904  C  C   . LEU A 1 117 ? 141.132 150.092 178.072 1.00 67.28  0  116 LEU A C   1 
ATOM   905  O  O   . LEU A 1 117 ? 140.267 150.973 178.057 1.00 67.28  0  116 LEU A O   1 
ATOM   906  C  CB  . LEU A 1 117 ? 140.782 147.773 178.961 1.00 67.28  0  116 LEU A CB  1 
ATOM   907  C  CG  . LEU A 1 117 ? 141.331 146.557 179.717 1.00 67.28  0  116 LEU A CG  1 
ATOM   908  C  CD1 . LEU A 1 117 ? 142.804 146.356 179.416 1.00 67.28  0  116 LEU A CD1 1 
ATOM   909  C  CD2 . LEU A 1 117 ? 141.091 146.654 181.215 1.00 67.28  0  116 LEU A CD2 1 
ATOM   910  N  N   . ASP A 1 118 ? 141.987 149.883 177.067 1.00 67.28  0  117 ASP A N   1 
ATOM   911  C  CA  . ASP A 1 118 ? 141.867 150.686 175.825 1.00 67.28  0  117 ASP A CA  1 
ATOM   912  C  C   . ASP A 1 118 ? 140.453 150.489 175.286 1.00 67.28  0  117 ASP A C   1 
ATOM   913  O  O   . ASP A 1 118 ? 139.936 149.359 175.375 1.00 67.28  0  117 ASP A O   1 
ATOM   914  C  CB  . ASP A 1 118 ? 142.982 150.373 174.822 1.00 67.28  0  117 ASP A CB  1 
ATOM   915  C  CG  . ASP A 1 118 ? 143.020 148.931 174.352 1.00 67.28  0  117 ASP A CG  1 
ATOM   916  O  OD1 . ASP A 1 118 ? 142.200 148.136 174.838 1.00 67.28  0  117 ASP A OD1 1 
ATOM   917  O  OD2 . ASP A 1 118 ? 143.880 148.614 173.506 1.00 67.28  -1 117 ASP A OD2 1 
ATOM   918  N  N   . CYS A 1 119 ? 139.853 151.547 174.763 1.00 67.28  0  118 CYS A N   1 
ATOM   919  C  CA  . CYS A 1 119 ? 138.475 151.517 174.293 1.00 67.28  0  118 CYS A CA  1 
ATOM   920  C  C   . CYS A 1 119 ? 138.334 150.947 172.889 1.00 67.28  0  118 CYS A C   1 
ATOM   921  O  O   . CYS A 1 119 ? 137.272 151.108 172.276 1.00 67.28  0  118 CYS A O   1 
ATOM   922  C  CB  . CYS A 1 119 ? 137.872 152.921 174.352 1.00 67.28  0  118 CYS A CB  1 
ATOM   923  S  SG  . CYS A 1 119 ? 137.706 153.575 176.025 1.00 67.28  0  118 CYS A SG  1 
ATOM   924  N  N   . ASP A 1 120 ? 139.366 150.294 172.365 1.00 67.47  0  119 ASP A N   1 
ATOM   925  C  CA  . ASP A 1 120 ? 139.249 149.606 171.092 1.00 67.47  0  119 ASP A CA  1 
ATOM   926  C  C   . ASP A 1 120 ? 138.500 148.286 171.267 1.00 67.47  0  119 ASP A C   1 
ATOM   927  O  O   . ASP A 1 120 ? 138.166 147.869 172.380 1.00 67.47  0  119 ASP A O   1 
ATOM   928  C  CB  . ASP A 1 120 ? 140.631 149.383 170.474 1.00 67.47  0  119 ASP A CB  1 
ATOM   929  C  CG  . ASP A 1 120 ? 141.526 148.491 171.323 1.00 67.47  0  119 ASP A CG  1 
ATOM   930  O  OD1 . ASP A 1 120 ? 141.106 148.068 172.420 1.00 67.47  0  119 ASP A OD1 1 
ATOM   931  O  OD2 . ASP A 1 120 ? 142.661 148.210 170.884 1.00 67.47  -1 119 ASP A OD2 1 
ATOM   932  N  N   . LYS A 1 121 ? 138.230 147.626 170.140 1.00 67.67  0  120 LYS A N   1 
ATOM   933  C  CA  . LYS A 1 121 ? 137.525 146.349 170.183 1.00 67.67  0  120 LYS A CA  1 
ATOM   934  C  C   . LYS A 1 121 ? 138.348 145.291 170.906 1.00 67.67  0  120 LYS A C   1 
ATOM   935  O  O   . LYS A 1 121 ? 137.799 144.457 171.636 1.00 67.67  0  120 LYS A O   1 
ATOM   936  C  CB  . LYS A 1 121 ? 137.183 145.895 168.765 1.00 67.67  0  120 LYS A CB  1 
ATOM   937  C  CG  . LYS A 1 121 ? 136.011 144.935 168.686 1.00 67.67  0  120 LYS A CG  1 
ATOM   938  C  CD  . LYS A 1 121 ? 135.477 144.832 167.268 1.00 67.67  0  120 LYS A CD  1 
ATOM   939  C  CE  . LYS A 1 121 ? 135.079 146.197 166.733 1.00 67.67  0  120 LYS A CE  1 
ATOM   940  N  NZ  . LYS A 1 121 ? 134.456 146.105 165.385 1.00 67.67  1  120 LYS A NZ  1 
ATOM   941  N  N   . GLU A 1 122 ? 139.671 145.351 170.747 1.00 67.54  0  121 GLU A N   1 
ATOM   942  C  CA  . GLU A 1 122 ? 140.567 144.357 171.398 1.00 67.54  0  121 GLU A CA  1 
ATOM   943  C  C   . GLU A 1 122 ? 140.538 144.557 172.913 1.00 67.54  0  121 GLU A C   1 
ATOM   944  O  O   . GLU A 1 122 ? 140.763 143.572 173.639 1.00 67.54  0  121 GLU A O   1 
ATOM   945  C  CB  . GLU A 1 122 ? 141.996 144.494 170.872 1.00 67.54  0  121 GLU A CB  1 
ATOM   946  C  CG  . GLU A 1 122 ? 142.845 143.259 171.106 1.00 67.54  0  121 GLU A CG  1 
ATOM   947  C  CD  . GLU A 1 122 ? 142.489 142.077 170.222 1.00 67.54  0  121 GLU A CD  1 
ATOM   948  O  OE1 . GLU A 1 122 ? 141.841 142.295 169.179 1.00 67.54  0  121 GLU A OE1 1 
ATOM   949  O  OE2 . GLU A 1 122 ? 142.861 140.942 170.578 1.00 67.54  -1 121 GLU A OE2 1 
ATOM   950  N  N   . GLY A 1 123 ? 140.273 145.783 173.370 1.00 67.77  0  122 GLY A N   1 
ATOM   951  C  CA  . GLY A 1 123 ? 140.290 146.042 174.798 1.00 67.77  0  122 GLY A CA  1 
ATOM   952  C  C   . GLY A 1 123 ? 139.171 145.356 175.554 1.00 67.77  0  122 GLY A C   1 
ATOM   953  O  O   . GLY A 1 123 ? 139.334 145.009 176.727 1.00 67.77  0  122 GLY A O   1 
ATOM   954  N  N   . GLU A 1 124 ? 138.023 145.152 174.904 1.00 67.82  0  123 GLU A N   1 
ATOM   955  C  CA  . GLU A 1 124 ? 136.910 144.485 175.573 1.00 67.82  0  123 GLU A CA  1 
ATOM   956  C  C   . GLU A 1 124 ? 137.225 143.023 175.863 1.00 67.82  0  123 GLU A C   1 
ATOM   957  O  O   . GLU A 1 124 ? 136.733 142.469 176.854 1.00 67.82  0  123 GLU A O   1 
ATOM   958  C  CB  . GLU A 1 124 ? 135.644 144.603 174.728 1.00 67.82  0  123 GLU A CB  1 
ATOM   959  C  CG  . GLU A 1 124 ? 135.297 146.029 174.338 1.00 67.82  0  123 GLU A CG  1 
ATOM   960  C  CD  . GLU A 1 124 ? 134.681 146.812 175.479 1.00 67.82  0  123 GLU A CD  1 
ATOM   961  O  OE1 . GLU A 1 124 ? 134.196 146.180 176.441 1.00 67.82  0  123 GLU A OE1 1 
ATOM   962  O  OE2 . GLU A 1 124 ? 134.681 148.059 175.415 1.00 67.82  -1 123 GLU A OE2 1 
ATOM   963  N  N   . ASN A 1 125 ? 138.037 142.386 175.018 1.00 67.49  0  124 ASN A N   1 
ATOM   964  C  CA  . ASN A 1 125 ? 138.466 141.020 175.296 1.00 67.49  0  124 ASN A CA  1 
ATOM   965  C  C   . ASN A 1 125 ? 139.259 140.953 176.595 1.00 67.49  0  124 ASN A C   1 
ATOM   966  O  O   . ASN A 1 125 ? 139.018 140.084 177.440 1.00 67.49  0  124 ASN A O   1 
ATOM   967  C  CB  . ASN A 1 125 ? 139.293 140.484 174.127 1.00 67.49  0  124 ASN A CB  1 
ATOM   968  C  CG  . ASN A 1 125 ? 139.320 138.972 174.078 1.00 67.49  0  124 ASN A CG  1 
ATOM   969  O  OD1 . ASN A 1 125 ? 138.361 138.310 174.473 1.00 67.49  0  124 ASN A OD1 1 
ATOM   970  N  ND2 . ASN A 1 125 ? 140.422 138.415 173.590 1.00 67.49  0  124 ASN A ND2 1 
ATOM   971  N  N   . ILE A 1 126 ? 140.205 141.878 176.777 1.00 67.89  0  125 ILE A N   1 
ATOM   972  C  CA  . ILE A 1 126 ? 140.967 141.925 178.021 1.00 67.89  0  125 ILE A CA  1 
ATOM   973  C  C   . ILE A 1 126 ? 140.058 142.289 179.186 1.00 67.89  0  125 ILE A C   1 
ATOM   974  O  O   . ILE A 1 126 ? 140.229 141.791 180.305 1.00 67.89  0  125 ILE A O   1 
ATOM   975  C  CB  . ILE A 1 126 ? 142.144 142.908 177.892 1.00 67.89  0  125 ILE A CB  1 
ATOM   976  C  CG1 . ILE A 1 126 ? 142.844 142.729 176.546 1.00 67.89  0  125 ILE A CG1 1 
ATOM   977  C  CG2 . ILE A 1 126 ? 143.129 142.707 179.030 1.00 67.89  0  125 ILE A CG2 1 
ATOM   978  C  CD1 . ILE A 1 126 ? 144.002 143.678 176.331 1.00 67.89  0  125 ILE A CD1 1 
ATOM   979  N  N   . CYS A 1 127 ? 139.082 143.166 178.942 1.00 69.09  0  126 CYS A N   1 
ATOM   980  C  CA  . CYS A 1 127 ? 138.117 143.527 179.976 1.00 69.09  0  126 CYS A CA  1 
ATOM   981  C  C   . CYS A 1 127 ? 137.389 142.296 180.499 1.00 69.09  0  126 CYS A C   1 
ATOM   982  O  O   . CYS A 1 127 ? 137.311 142.069 181.712 1.00 69.09  0  126 CYS A O   1 
ATOM   983  C  CB  . CYS A 1 127 ? 137.122 144.545 179.415 1.00 69.09  0  126 CYS A CB  1 
ATOM   984  S  SG  . CYS A 1 127 ? 135.888 145.154 180.586 1.00 69.09  0  126 CYS A SG  1 
ATOM   985  N  N   . PHE A 1 128 ? 136.871 141.471 179.592 1.00 67.65  0  127 PHE A N   1 
ATOM   986  C  CA  . PHE A 1 128 ? 136.130 140.290 180.017 1.00 67.65  0  127 PHE A CA  1 
ATOM   987  C  C   . PHE A 1 128 ? 137.039 139.188 180.542 1.00 67.65  0  127 PHE A C   1 
ATOM   988  O  O   . PHE A 1 128 ? 136.612 138.402 181.392 1.00 67.65  0  127 PHE A O   1 
ATOM   989  C  CB  . PHE A 1 128 ? 135.254 139.780 178.875 1.00 67.65  0  127 PHE A CB  1 
ATOM   990  C  CG  . PHE A 1 128 ? 133.908 140.435 178.824 1.00 67.65  0  127 PHE A CG  1 
ATOM   991  C  CD1 . PHE A 1 128 ? 133.035 140.324 179.891 1.00 67.65  0  127 PHE A CD1 1 
ATOM   992  C  CD2 . PHE A 1 128 ? 133.515 141.161 177.717 1.00 67.65  0  127 PHE A CD2 1 
ATOM   993  C  CE1 . PHE A 1 128 ? 131.795 140.924 179.856 1.00 67.65  0  127 PHE A CE1 1 
ATOM   994  C  CE2 . PHE A 1 128 ? 132.278 141.767 177.678 1.00 67.65  0  127 PHE A CE2 1 
ATOM   995  C  CZ  . PHE A 1 128 ? 131.416 141.646 178.746 1.00 67.65  0  127 PHE A CZ  1 
ATOM   996  N  N   . GLU A 1 129 ? 138.289 139.117 180.081 1.00 70.68  0  128 GLU A N   1 
ATOM   997  C  CA  . GLU A 1 129 ? 139.231 138.185 180.694 1.00 70.68  0  128 GLU A CA  1 
ATOM   998  C  C   . GLU A 1 129 ? 139.518 138.568 182.143 1.00 70.68  0  128 GLU A C   1 
ATOM   999  O  O   . GLU A 1 129 ? 139.541 137.705 183.030 1.00 70.68  0  128 GLU A O   1 
ATOM   1000 C  CB  . GLU A 1 129 ? 140.523 138.134 179.881 1.00 70.68  0  128 GLU A CB  1 
ATOM   1001 C  CG  . GLU A 1 129 ? 140.385 137.455 178.530 1.00 70.68  0  128 GLU A CG  1 
ATOM   1002 C  CD  . GLU A 1 129 ? 141.586 137.692 177.636 1.00 70.68  0  128 GLU A CD  1 
ATOM   1003 O  OE1 . GLU A 1 129 ? 142.164 138.798 177.694 1.00 70.68  0  128 GLU A OE1 1 
ATOM   1004 O  OE2 . GLU A 1 129 ? 141.949 136.774 176.871 1.00 70.68  -1 128 GLU A OE2 1 
ATOM   1005 N  N   . VAL A 1 130 ? 139.720 139.862 182.403 1.00 67.28  0  129 VAL A N   1 
ATOM   1006 C  CA  . VAL A 1 130 ? 139.912 140.328 183.774 1.00 67.28  0  129 VAL A CA  1 
ATOM   1007 C  C   . VAL A 1 130 ? 138.659 140.074 184.600 1.00 67.28  0  129 VAL A C   1 
ATOM   1008 O  O   . VAL A 1 130 ? 138.737 139.706 185.778 1.00 67.28  0  129 VAL A O   1 
ATOM   1009 C  CB  . VAL A 1 130 ? 140.309 141.817 183.781 1.00 67.28  0  129 VAL A CB  1 
ATOM   1010 C  CG1 . VAL A 1 130 ? 140.260 142.379 185.192 1.00 67.28  0  129 VAL A CG1 1 
ATOM   1011 C  CG2 . VAL A 1 130 ? 141.696 141.996 183.186 1.00 67.28  0  129 VAL A CG2 1 
ATOM   1012 N  N   . LEU A 1 131 ? 137.483 140.270 183.998 1.00 68.49  0  130 LEU A N   1 
ATOM   1013 C  CA  . LEU A 1 131 ? 136.237 139.987 184.702 1.00 68.49  0  130 LEU A CA  1 
ATOM   1014 C  C   . LEU A 1 131 ? 136.134 138.512 185.072 1.00 68.49  0  130 LEU A C   1 
ATOM   1015 O  O   . LEU A 1 131 ? 135.746 138.172 186.194 1.00 68.49  0  130 LEU A O   1 
ATOM   1016 C  CB  . LEU A 1 131 ? 135.044 140.407 183.847 1.00 68.49  0  130 LEU A CB  1 
ATOM   1017 C  CG  . LEU A 1 131 ? 134.684 141.891 183.881 1.00 68.49  0  130 LEU A CG  1 
ATOM   1018 C  CD1 . LEU A 1 131 ? 133.496 142.171 182.976 1.00 68.49  0  130 LEU A CD1 1 
ATOM   1019 C  CD2 . LEU A 1 131 ? 134.398 142.332 185.306 1.00 68.49  0  130 LEU A CD2 1 
ATOM   1020 N  N   . ASP A 1 132 ? 136.484 137.621 184.143 1.00 71.15  0  131 ASP A N   1 
ATOM   1021 C  CA  . ASP A 1 132 ? 136.477 136.194 184.443 1.00 71.15  0  131 ASP A CA  1 
ATOM   1022 C  C   . ASP A 1 132 ? 137.484 135.850 185.530 1.00 71.15  0  131 ASP A C   1 
ATOM   1023 O  O   . ASP A 1 132 ? 137.239 134.951 186.342 1.00 71.15  0  131 ASP A O   1 
ATOM   1024 C  CB  . ASP A 1 132 ? 136.769 135.390 183.175 1.00 71.15  0  131 ASP A CB  1 
ATOM   1025 C  CG  . ASP A 1 132 ? 136.273 133.961 183.263 1.00 71.15  0  131 ASP A CG  1 
ATOM   1026 O  OD1 . ASP A 1 132 ? 135.615 133.618 184.267 1.00 71.15  0  131 ASP A OD1 1 
ATOM   1027 O  OD2 . ASP A 1 132 ? 136.541 133.180 182.326 1.00 71.15  -1 131 ASP A OD2 1 
ATOM   1028 N  N   . ALA A 1 133 ? 138.617 136.550 185.561 1.00 70.24  0  132 ALA A N   1 
ATOM   1029 C  CA  . ALA A 1 133 ? 139.631 136.272 186.570 1.00 70.24  0  132 ALA A CA  1 
ATOM   1030 C  C   . ALA A 1 133 ? 139.243 136.785 187.953 1.00 70.24  0  132 ALA A C   1 
ATOM   1031 O  O   . ALA A 1 133 ? 139.614 136.170 188.959 1.00 70.24  0  132 ALA A O   1 
ATOM   1032 C  CB  . ALA A 1 133 ? 140.970 136.879 186.149 1.00 70.24  0  132 ALA A CB  1 
ATOM   1033 N  N   . VAL A 1 134 ? 138.508 137.893 188.032 1.00 69.30  0  133 VAL A N   1 
ATOM   1034 C  CA  . VAL A 1 134 ? 138.287 138.567 189.306 1.00 69.30  0  133 VAL A CA  1 
ATOM   1035 C  C   . VAL A 1 134 ? 136.884 138.355 189.875 1.00 69.30  0  133 VAL A C   1 
ATOM   1036 O  O   . VAL A 1 134 ? 136.701 138.525 191.090 1.00 69.30  0  133 VAL A O   1 
ATOM   1037 C  CB  . VAL A 1 134 ? 138.587 140.077 189.189 1.00 69.30  0  133 VAL A CB  1 
ATOM   1038 C  CG1 . VAL A 1 134 ? 137.466 140.786 188.450 1.00 69.30  0  133 VAL A CG1 1 
ATOM   1039 C  CG2 . VAL A 1 134 ? 138.828 140.698 190.560 1.00 69.30  0  133 VAL A CG2 1 
ATOM   1040 N  N   . LEU A 1 135 ? 135.899 137.986 189.058 1.00 69.93  0  134 LEU A N   1 
ATOM   1041 C  CA  . LEU A 1 135 ? 134.527 137.895 189.555 1.00 69.93  0  134 LEU A CA  1 
ATOM   1042 C  C   . LEU A 1 135 ? 134.343 136.915 190.711 1.00 69.93  0  134 LEU A C   1 
ATOM   1043 O  O   . LEU A 1 135 ? 133.658 137.281 191.682 1.00 69.93  0  134 LEU A O   1 
ATOM   1044 C  CB  . LEU A 1 135 ? 133.577 137.550 188.400 1.00 69.93  0  134 LEU A CB  1 
ATOM   1045 C  CG  . LEU A 1 135 ? 132.993 138.726 187.611 1.00 69.93  0  134 LEU A CG  1 
ATOM   1046 C  CD1 . LEU A 1 135 ? 131.844 138.264 186.728 1.00 69.93  0  134 LEU A CD1 1 
ATOM   1047 C  CD2 . LEU A 1 135 ? 132.540 139.834 188.544 1.00 69.93  0  134 LEU A CD2 1 
ATOM   1048 N  N   . PRO A 1 136 ? 134.887 135.692 190.689 1.00 69.99  0  135 PRO A N   1 
ATOM   1049 C  CA  . PRO A 1 136 ? 134.631 134.769 191.808 1.00 69.99  0  135 PRO A CA  1 
ATOM   1050 C  C   . PRO A 1 136 ? 135.178 135.236 193.148 1.00 69.99  0  135 PRO A C   1 
ATOM   1051 O  O   . PRO A 1 136 ? 134.704 134.757 194.186 1.00 69.99  0  135 PRO A O   1 
ATOM   1052 C  CB  . PRO A 1 136 ? 135.309 133.468 191.355 1.00 69.99  0  135 PRO A CB  1 
ATOM   1053 C  CG  . PRO A 1 136 ? 135.398 133.580 189.878 1.00 69.99  0  135 PRO A CG  1 
ATOM   1054 C  CD  . PRO A 1 136 ? 135.647 135.027 189.616 1.00 69.99  0  135 PRO A CD  1 
ATOM   1055 N  N   . VAL A 1 137 ? 136.152 136.147 193.173 1.00 69.89  0  136 VAL A N   1 
ATOM   1056 C  CA  . VAL A 1 137 ? 136.822 136.512 194.416 1.00 69.89  0  136 VAL A CA  1 
ATOM   1057 C  C   . VAL A 1 137 ? 136.331 137.846 194.972 1.00 69.89  0  136 VAL A C   1 
ATOM   1058 O  O   . VAL A 1 137 ? 136.880 138.334 195.963 1.00 69.89  0  136 VAL A O   1 
ATOM   1059 C  CB  . VAL A 1 137 ? 138.351 136.524 194.244 1.00 69.89  0  136 VAL A CB  1 
ATOM   1060 C  CG1 . VAL A 1 137 ? 138.854 135.138 193.870 1.00 69.89  0  136 VAL A CG1 1 
ATOM   1061 C  CG2 . VAL A 1 137 ? 138.771 137.554 193.210 1.00 69.89  0  136 VAL A CG2 1 
ATOM   1062 N  N   . MET A 1 138 ? 135.312 138.448 194.365 1.00 70.23  0  137 MET A N   1 
ATOM   1063 C  CA  . MET A 1 138 ? 134.733 139.674 194.890 1.00 70.23  0  137 MET A CA  1 
ATOM   1064 C  C   . MET A 1 138 ? 133.490 139.356 195.718 1.00 70.23  0  137 MET A C   1 
ATOM   1065 O  O   . MET A 1 138 ? 133.062 138.206 195.838 1.00 70.23  0  137 MET A O   1 
ATOM   1066 C  CB  . MET A 1 138 ? 134.403 140.652 193.761 1.00 70.23  0  137 MET A CB  1 
ATOM   1067 C  CG  . MET A 1 138 ? 135.530 140.870 192.771 1.00 70.23  0  137 MET A CG  1 
ATOM   1068 S  SD  . MET A 1 138 ? 135.150 142.143 191.552 1.00 70.23  0  137 MET A SD  1 
ATOM   1069 C  CE  . MET A 1 138 ? 133.380 141.940 191.390 1.00 70.23  0  137 MET A CE  1 
ATOM   1070 N  N   . ASN A 1 139 ? 132.906 140.400 196.300 1.00 69.38  0  138 ASN A N   1 
ATOM   1071 C  CA  . ASN A 1 139 ? 131.721 140.243 197.129 1.00 69.38  0  138 ASN A CA  1 
ATOM   1072 C  C   . ASN A 1 139 ? 130.481 140.060 196.265 1.00 69.38  0  138 ASN A C   1 
ATOM   1073 O  O   . ASN A 1 139 ? 130.352 140.668 195.199 1.00 69.38  0  138 ASN A O   1 
ATOM   1074 C  CB  . ASN A 1 139 ? 131.546 141.453 198.046 1.00 69.38  0  138 ASN A CB  1 
ATOM   1075 C  CG  . ASN A 1 139 ? 132.506 141.439 199.218 1.00 69.38  0  138 ASN A CG  1 
ATOM   1076 O  OD1 . ASN A 1 139 ? 133.717 141.570 199.045 1.00 69.38  0  138 ASN A OD1 1 
ATOM   1077 N  ND2 . ASN A 1 139 ? 131.968 141.283 200.422 1.00 69.38  0  138 ASN A ND2 1 
ATOM   1078 N  N   . LYS A 1 140 ? 129.566 139.211 196.736 1.00 74.04  0  139 LYS A N   1 
ATOM   1079 C  CA  . LYS A 1 140 ? 128.332 138.950 196.005 1.00 74.04  0  139 LYS A CA  1 
ATOM   1080 C  C   . LYS A 1 140 ? 127.384 140.144 196.039 1.00 74.04  0  139 LYS A C   1 
ATOM   1081 O  O   . LYS A 1 140 ? 126.462 140.210 195.218 1.00 74.04  0  139 LYS A O   1 
ATOM   1082 C  CB  . LYS A 1 140 ? 127.665 137.691 196.576 1.00 74.04  0  139 LYS A CB  1 
ATOM   1083 C  CG  . LYS A 1 140 ? 126.393 137.217 195.873 1.00 74.04  0  139 LYS A CG  1 
ATOM   1084 C  CD  . LYS A 1 140 ? 125.133 137.706 196.576 1.00 74.04  0  139 LYS A CD  1 
ATOM   1085 C  CE  . LYS A 1 140 ? 124.935 137.003 197.909 1.00 74.04  0  139 LYS A CE  1 
ATOM   1086 N  NZ  . LYS A 1 140 ? 123.700 137.465 198.601 1.00 74.04  1  139 LYS A NZ  1 
ATOM   1087 N  N   . ALA A 1 141 ? 127.605 141.088 196.960 1.00 75.07  0  140 ALA A N   1 
ATOM   1088 C  CA  . ALA A 1 141 ? 126.778 142.279 197.138 1.00 75.07  0  140 ALA A CA  1 
ATOM   1089 C  C   . ALA A 1 141 ? 125.377 141.916 197.616 1.00 75.07  0  140 ALA A C   1 
ATOM   1090 O  O   . ALA A 1 141 ? 125.011 140.737 197.658 1.00 75.07  0  140 ALA A O   1 
ATOM   1091 C  CB  . ALA A 1 141 ? 126.708 143.103 195.848 1.00 75.07  0  140 ALA A CB  1 
ATOM   1092 N  N   . HIS A 1 142 ? 124.588 142.924 197.990 1.00 78.27  0  141 HIS A N   1 
ATOM   1093 C  CA  . HIS A 1 142 ? 123.262 142.670 198.535 1.00 78.27  0  141 HIS A CA  1 
ATOM   1094 C  C   . HIS A 1 142 ? 122.264 142.232 197.472 1.00 78.27  0  141 HIS A C   1 
ATOM   1095 O  O   . HIS A 1 142 ? 121.272 141.575 197.808 1.00 78.27  0  141 HIS A O   1 
ATOM   1096 C  CB  . HIS A 1 142 ? 122.741 143.917 199.253 1.00 78.27  0  141 HIS A CB  1 
ATOM   1097 C  CG  . HIS A 1 142 ? 123.541 144.298 200.460 1.00 78.27  0  141 HIS A CG  1 
ATOM   1098 N  ND1 . HIS A 1 142 ? 124.635 145.133 200.394 1.00 78.27  0  141 HIS A ND1 1 
ATOM   1099 C  CD2 . HIS A 1 142 ? 123.407 143.956 201.763 1.00 78.27  0  141 HIS A CD2 1 
ATOM   1100 C  CE1 . HIS A 1 142 ? 125.140 145.290 201.604 1.00 78.27  0  141 HIS A CE1 1 
ATOM   1101 N  NE2 . HIS A 1 142 ? 124.414 144.587 202.453 1.00 78.27  0  141 HIS A NE2 1 
ATOM   1102 N  N   . GLY A 1 143 ? 122.497 142.576 196.208 1.00 73.42  0  142 GLY A N   1 
ATOM   1103 C  CA  . GLY A 1 143 ? 121.635 142.119 195.137 1.00 73.42  0  142 GLY A CA  1 
ATOM   1104 C  C   . GLY A 1 143 ? 121.076 143.225 194.266 1.00 73.42  0  142 GLY A C   1 
ATOM   1105 O  O   . GLY A 1 143 ? 120.448 144.164 194.766 1.00 73.42  0  142 GLY A O   1 
ATOM   1106 N  N   . GLY A 1 144 ? 121.300 143.123 192.956 1.00 72.33  0  143 GLY A N   1 
ATOM   1107 C  CA  . GLY A 1 144 ? 120.751 144.045 191.989 1.00 72.33  0  143 GLY A CA  1 
ATOM   1108 C  C   . GLY A 1 144 ? 121.618 145.250 191.684 1.00 72.33  0  143 GLY A C   1 
ATOM   1109 O  O   . GLY A 1 144 ? 121.543 145.787 190.574 1.00 72.33  0  143 GLY A O   1 
ATOM   1110 N  N   . GLU A 1 145 ? 122.433 145.691 192.638 1.00 71.99  0  144 GLU A N   1 
ATOM   1111 C  CA  . GLU A 1 145 ? 123.262 146.869 192.428 1.00 71.99  0  144 GLU A CA  1 
ATOM   1112 C  C   . GLU A 1 145 ? 124.332 146.597 191.379 1.00 71.99  0  144 GLU A C   1 
ATOM   1113 O  O   . GLU A 1 145 ? 124.960 145.535 191.367 1.00 71.99  0  144 GLU A O   1 
ATOM   1114 C  CB  . GLU A 1 145 ? 123.913 147.307 193.740 1.00 71.99  0  144 GLU A CB  1 
ATOM   1115 C  CG  . GLU A 1 145 ? 123.006 147.196 194.956 1.00 71.99  0  144 GLU A CG  1 
ATOM   1116 C  CD  . GLU A 1 145 ? 123.029 145.817 195.586 1.00 71.99  0  144 GLU A CD  1 
ATOM   1117 O  OE1 . GLU A 1 145 ? 123.603 144.889 194.979 1.00 71.99  0  144 GLU A OE1 1 
ATOM   1118 O  OE2 . GLU A 1 145 ? 122.461 145.661 196.686 1.00 71.99  -1 144 GLU A OE2 1 
ATOM   1119 N  N   . LYS A 1 146 ? 124.530 147.567 190.490 1.00 67.28  0  145 LYS A N   1 
ATOM   1120 C  CA  . LYS A 1 146 ? 125.532 147.436 189.442 1.00 67.28  0  145 LYS A CA  1 
ATOM   1121 C  C   . LYS A 1 146 ? 126.928 147.384 190.052 1.00 67.28  0  145 LYS A C   1 
ATOM   1122 O  O   . LYS A 1 146 ? 127.275 148.203 190.908 1.00 67.28  0  145 LYS A O   1 
ATOM   1123 C  CB  . LYS A 1 146 ? 125.421 148.602 188.461 1.00 67.28  0  145 LYS A CB  1 
ATOM   1124 C  CG  . LYS A 1 146 ? 126.336 148.495 187.254 1.00 67.28  0  145 LYS A CG  1 
ATOM   1125 C  CD  . LYS A 1 146 ? 126.213 149.722 186.365 1.00 67.28  0  145 LYS A CD  1 
ATOM   1126 C  CE  . LYS A 1 146 ? 124.905 149.722 185.592 1.00 67.28  0  145 LYS A CE  1 
ATOM   1127 N  NZ  . LYS A 1 146 ? 124.828 150.858 184.632 1.00 67.28  1  145 LYS A NZ  1 
ATOM   1128 N  N   . THR A 1 147 ? 127.728 146.416 189.611 1.00 67.28  0  146 THR A N   1 
ATOM   1129 C  CA  . THR A 1 147 ? 129.081 146.220 190.114 1.00 67.28  0  146 THR A CA  1 
ATOM   1130 C  C   . THR A 1 147 ? 130.143 146.447 189.049 1.00 67.28  0  146 THR A C   1 
ATOM   1131 O  O   . THR A 1 147 ? 131.081 147.222 189.264 1.00 67.28  0  146 THR A O   1 
ATOM   1132 C  CB  . THR A 1 147 ? 129.226 144.807 190.696 1.00 67.28  0  146 THR A CB  1 
ATOM   1133 O  OG1 . THR A 1 147 ? 128.452 144.701 191.898 1.00 67.28  0  146 THR A OG1 1 
ATOM   1134 C  CG2 . THR A 1 147 ? 130.682 144.500 191.005 1.00 67.28  0  146 THR A CG2 1 
ATOM   1135 N  N   . VAL A 1 148 ? 130.019 145.788 187.899 1.00 67.28  0  147 VAL A N   1 
ATOM   1136 C  CA  . VAL A 1 148 ? 130.978 145.973 186.817 1.00 67.28  0  147 VAL A CA  1 
ATOM   1137 C  C   . VAL A 1 148 ? 130.717 147.306 186.131 1.00 67.28  0  147 VAL A C   1 
ATOM   1138 O  O   . VAL A 1 148 ? 129.572 147.641 185.802 1.00 67.28  0  147 VAL A O   1 
ATOM   1139 C  CB  . VAL A 1 148 ? 130.895 144.810 185.820 1.00 67.28  0  147 VAL A CB  1 
ATOM   1140 C  CG1 . VAL A 1 148 ? 131.931 144.979 184.722 1.00 67.28  0  147 VAL A CG1 1 
ATOM   1141 C  CG2 . VAL A 1 148 ? 131.080 143.483 186.539 1.00 67.28  0  147 VAL A CG2 1 
ATOM   1142 N  N   . PHE A 1 149 ? 131.781 148.074 185.913 1.00 67.28  0  148 PHE A N   1 
ATOM   1143 C  CA  . PHE A 1 149 ? 131.695 149.355 185.231 1.00 67.28  0  148 PHE A CA  1 
ATOM   1144 C  C   . PHE A 1 149 ? 132.740 149.409 184.127 1.00 67.28  0  148 PHE A C   1 
ATOM   1145 O  O   . PHE A 1 149 ? 133.752 148.705 184.163 1.00 67.28  0  148 PHE A O   1 
ATOM   1146 C  CB  . PHE A 1 149 ? 131.901 150.527 186.196 1.00 67.28  0  148 PHE A CB  1 
ATOM   1147 C  CG  . PHE A 1 149 ? 130.716 150.818 187.070 1.00 67.28  0  148 PHE A CG  1 
ATOM   1148 C  CD1 . PHE A 1 149 ? 130.575 150.194 188.297 1.00 67.28  0  148 PHE A CD1 1 
ATOM   1149 C  CD2 . PHE A 1 149 ? 129.750 151.724 186.670 1.00 67.28  0  148 PHE A CD2 1 
ATOM   1150 C  CE1 . PHE A 1 149 ? 129.491 150.462 189.106 1.00 67.28  0  148 PHE A CE1 1 
ATOM   1151 C  CE2 . PHE A 1 149 ? 128.663 151.998 187.477 1.00 67.28  0  148 PHE A CE2 1 
ATOM   1152 C  CZ  . PHE A 1 149 ? 128.533 151.365 188.696 1.00 67.28  0  148 PHE A CZ  1 
ATOM   1153 N  N   . ARG A 1 150 ? 132.479 150.257 183.137 1.00 67.28  0  149 ARG A N   1 
ATOM   1154 C  CA  . ARG A 1 150 ? 133.379 150.457 182.012 1.00 67.28  0  149 ARG A CA  1 
ATOM   1155 C  C   . ARG A 1 150 ? 133.611 151.946 181.812 1.00 67.28  0  149 ARG A C   1 
ATOM   1156 O  O   . ARG A 1 150 ? 132.661 152.735 181.802 1.00 67.28  0  149 ARG A O   1 
ATOM   1157 C  CB  . ARG A 1 150 ? 132.813 149.835 180.731 1.00 67.28  0  149 ARG A CB  1 
ATOM   1158 C  CG  . ARG A 1 150 ? 133.637 150.102 179.485 1.00 67.28  0  149 ARG A CG  1 
ATOM   1159 C  CD  . ARG A 1 150 ? 135.012 149.469 179.585 1.00 67.28  0  149 ARG A CD  1 
ATOM   1160 N  NE  . ARG A 1 150 ? 135.780 149.641 178.358 1.00 67.28  0  149 ARG A NE  1 
ATOM   1161 C  CZ  . ARG A 1 150 ? 137.100 149.545 178.283 1.00 67.28  0  149 ARG A CZ  1 
ATOM   1162 N  NH1 . ARG A 1 150 ? 137.835 149.278 179.350 1.00 67.28  1  149 ARG A NH1 1 
ATOM   1163 N  NH2 . ARG A 1 150 ? 137.697 149.724 177.108 1.00 67.28  0  149 ARG A NH2 1 
ATOM   1164 N  N   . ALA A 1 151 ? 134.875 152.326 181.650 1.00 67.28  0  150 ALA A N   1 
ATOM   1165 C  CA  . ALA A 1 151 ? 135.263 153.716 181.453 1.00 67.28  0  150 ALA A CA  1 
ATOM   1166 C  C   . ALA A 1 151 ? 135.620 153.922 179.989 1.00 67.28  0  150 ALA A C   1 
ATOM   1167 O  O   . ALA A 1 151 ? 136.470 153.207 179.448 1.00 67.28  0  150 ALA A O   1 
ATOM   1168 C  CB  . ALA A 1 151 ? 136.438 154.092 182.354 1.00 67.28  0  150 ALA A CB  1 
ATOM   1169 N  N   . ARG A 1 152 ? 134.975 154.895 179.354 1.00 67.28  0  151 ARG A N   1 
ATOM   1170 C  CA  . ARG A 1 152 ? 135.212 155.208 177.952 1.00 67.28  0  151 ARG A CA  1 
ATOM   1171 C  C   . ARG A 1 152 ? 135.979 156.520 177.855 1.00 67.28  0  151 ARG A C   1 
ATOM   1172 O  O   . ARG A 1 152 ? 135.531 157.548 178.374 1.00 67.28  0  151 ARG A O   1 
ATOM   1173 C  CB  . ARG A 1 152 ? 133.897 155.284 177.178 1.00 67.28  0  151 ARG A CB  1 
ATOM   1174 C  CG  . ARG A 1 152 ? 133.159 153.958 177.118 1.00 67.28  0  151 ARG A CG  1 
ATOM   1175 C  CD  . ARG A 1 152 ? 133.352 153.286 175.766 1.00 67.28  0  151 ARG A CD  1 
ATOM   1176 N  NE  . ARG A 1 152 ? 133.157 151.842 175.833 1.00 67.28  0  151 ARG A NE  1 
ATOM   1177 C  CZ  . ARG A 1 152 ? 131.978 151.245 175.938 1.00 67.28  0  151 ARG A CZ  1 
ATOM   1178 N  NH1 . ARG A 1 152 ? 130.853 151.938 175.990 1.00 67.28  1  151 ARG A NH1 1 
ATOM   1179 N  NH2 . ARG A 1 152 ? 131.927 149.917 175.991 1.00 67.28  0  151 ARG A NH2 1 
ATOM   1180 N  N   . PHE A 1 153 ? 137.129 156.476 177.190 1.00 67.28  0  152 PHE A N   1 
ATOM   1181 C  CA  . PHE A 1 153 ? 138.015 157.623 177.085 1.00 67.28  0  152 PHE A CA  1 
ATOM   1182 C  C   . PHE A 1 153 ? 138.879 157.465 175.843 1.00 67.28  0  152 PHE A C   1 
ATOM   1183 O  O   . PHE A 1 153 ? 139.012 156.370 175.291 1.00 67.28  0  152 PHE A O   1 
ATOM   1184 C  CB  . PHE A 1 153 ? 138.870 157.774 178.349 1.00 67.28  0  152 PHE A CB  1 
ATOM   1185 C  CG  . PHE A 1 153 ? 139.800 156.621 178.592 1.00 67.28  0  152 PHE A CG  1 
ATOM   1186 C  CD1 . PHE A 1 153 ? 139.384 155.532 179.338 1.00 67.28  0  152 PHE A CD1 1 
ATOM   1187 C  CD2 . PHE A 1 153 ? 141.086 156.624 178.084 1.00 67.28  0  152 PHE A CD2 1 
ATOM   1188 C  CE1 . PHE A 1 153 ? 140.229 154.466 179.565 1.00 67.28  0  152 PHE A CE1 1 
ATOM   1189 C  CE2 . PHE A 1 153 ? 141.934 155.560 178.310 1.00 67.28  0  152 PHE A CE2 1 
ATOM   1190 C  CZ  . PHE A 1 153 ? 141.506 154.481 179.052 1.00 67.28  0  152 PHE A CZ  1 
ATOM   1191 N  N   . SER A 1 154 ? 139.467 158.575 175.408 1.00 67.28  0  153 SER A N   1 
ATOM   1192 C  CA  . SER A 1 154 ? 140.286 158.592 174.205 1.00 67.28  0  153 SER A CA  1 
ATOM   1193 C  C   . SER A 1 154 ? 141.684 159.146 174.418 1.00 67.28  0  153 SER A C   1 
ATOM   1194 O  O   . SER A 1 154 ? 142.606 158.734 173.710 1.00 67.28  0  153 SER A O   1 
ATOM   1195 C  CB  . SER A 1 154 ? 139.593 159.407 173.103 1.00 67.28  0  153 SER A CB  1 
ATOM   1196 O  OG  . SER A 1 154 ? 138.322 158.861 172.798 1.00 67.28  0  153 SER A OG  1 
ATOM   1197 N  N   . SER A 1 155 ? 141.870 160.061 175.364 1.00 67.28  0  154 SER A N   1 
ATOM   1198 C  CA  . SER A 1 155 ? 143.180 160.620 175.661 1.00 67.28  0  154 SER A CA  1 
ATOM   1199 C  C   . SER A 1 155 ? 143.411 160.575 177.162 1.00 67.28  0  154 SER A C   1 
ATOM   1200 O  O   . SER A 1 155 ? 142.472 160.738 177.946 1.00 67.28  0  154 SER A O   1 
ATOM   1201 C  CB  . SER A 1 155 ? 143.305 162.061 175.152 1.00 67.28  0  154 SER A CB  1 
ATOM   1202 O  OG  . SER A 1 155 ? 142.606 162.961 175.993 1.00 67.28  0  154 SER A OG  1 
ATOM   1203 N  N   . ILE A 1 156 ? 144.660 160.352 177.556 1.00 67.28  0  155 ILE A N   1 
ATOM   1204 C  CA  . ILE A 1 156 ? 145.027 160.333 178.982 1.00 67.28  0  155 ILE A CA  1 
ATOM   1205 C  C   . ILE A 1 156 ? 145.341 161.778 179.349 1.00 67.28  0  155 ILE A C   1 
ATOM   1206 O  O   . ILE A 1 156 ? 146.489 162.229 179.357 1.00 67.28  0  155 ILE A O   1 
ATOM   1207 C  CB  . ILE A 1 156 ? 146.192 159.381 179.267 1.00 67.28  0  155 ILE A CB  1 
ATOM   1208 C  CG1 . ILE A 1 156 ? 145.832 157.960 178.842 1.00 67.28  0  155 ILE A CG1 1 
ATOM   1209 C  CG2 . ILE A 1 156 ? 146.546 159.394 180.744 1.00 67.28  0  155 ILE A CG2 1 
ATOM   1210 C  CD1 . ILE A 1 156 ? 144.642 157.395 179.579 1.00 67.28  0  155 ILE A CD1 1 
ATOM   1211 N  N   . THR A 1 157 ? 144.286 162.531 179.659 1.00 67.28  0  156 THR A N   1 
ATOM   1212 C  CA  . THR A 1 157 ? 144.422 163.939 179.997 1.00 67.28  0  156 THR A CA  1 
ATOM   1213 C  C   . THR A 1 157 ? 143.465 164.302 181.125 1.00 67.28  0  156 THR A C   1 
ATOM   1214 O  O   . THR A 1 157 ? 142.496 163.587 181.418 1.00 67.28  0  156 THR A O   1 
ATOM   1215 C  CB  . THR A 1 157 ? 144.173 164.858 178.787 1.00 67.28  0  156 THR A CB  1 
ATOM   1216 O  OG1 . THR A 1 157 ? 142.915 164.539 178.183 1.00 67.28  0  156 THR A OG1 1 
ATOM   1217 C  CG2 . THR A 1 157 ? 145.285 164.726 177.752 1.00 67.28  0  156 THR A CG2 1 
ATOM   1218 N  N   . ASP A 1 158 ? 143.779 165.425 181.770 1.00 67.28  0  157 ASP A N   1 
ATOM   1219 C  CA  . ASP A 1 158 ? 142.983 165.918 182.882 1.00 67.28  0  157 ASP A CA  1 
ATOM   1220 C  C   . ASP A 1 158 ? 141.622 166.387 182.384 1.00 67.28  0  157 ASP A C   1 
ATOM   1221 O  O   . ASP A 1 158 ? 141.499 166.951 181.293 1.00 67.28  0  157 ASP A O   1 
ATOM   1222 C  CB  . ASP A 1 158 ? 143.715 167.058 183.592 1.00 67.28  0  157 ASP A CB  1 
ATOM   1223 C  CG  . ASP A 1 158 ? 143.092 167.417 184.933 1.00 67.28  0  157 ASP A CG  1 
ATOM   1224 O  OD1 . ASP A 1 158 ? 141.905 167.101 185.160 1.00 67.28  0  157 ASP A OD1 1 
ATOM   1225 O  OD2 . ASP A 1 158 ? 143.799 168.018 185.769 1.00 67.28  -1 157 ASP A OD2 1 
ATOM   1226 N  N   . THR A 1 159 ? 140.598 166.106 183.191 1.00 68.01  0  158 THR A N   1 
ATOM   1227 C  CA  . THR A 1 159 ? 139.186 166.393 182.949 1.00 68.01  0  158 THR A CA  1 
ATOM   1228 C  C   . THR A 1 159 ? 138.640 165.478 181.860 1.00 68.01  0  158 THR A C   1 
ATOM   1229 O  O   . THR A 1 159 ? 137.436 165.212 181.819 1.00 68.01  0  158 THR A O   1 
ATOM   1230 C  CB  . THR A 1 159 ? 138.972 167.867 182.580 1.00 68.01  0  158 THR A CB  1 
ATOM   1231 O  OG1 . THR A 1 159 ? 139.740 168.696 183.461 1.00 68.01  0  158 THR A OG1 1 
ATOM   1232 C  CG2 . THR A 1 159 ? 137.500 168.245 182.697 1.00 68.01  0  158 THR A CG2 1 
ATOM   1233 N  N   . ASP A 1 160 ? 139.530 164.842 181.099 1.00 67.28  0  159 ASP A N   1 
ATOM   1234 C  CA  . ASP A 1 160 ? 139.091 163.801 180.180 1.00 67.28  0  159 ASP A CA  1 
ATOM   1235 C  C   . ASP A 1 160 ? 138.919 162.491 180.933 1.00 67.28  0  159 ASP A C   1 
ATOM   1236 O  O   . ASP A 1 160 ? 137.906 161.800 180.776 1.00 67.28  0  159 ASP A O   1 
ATOM   1237 C  CB  . ASP A 1 160 ? 140.090 163.651 179.032 1.00 67.28  0  159 ASP A CB  1 
ATOM   1238 C  CG  . ASP A 1 160 ? 139.549 162.821 177.881 1.00 67.28  0  159 ASP A CG  1 
ATOM   1239 O  OD1 . ASP A 1 160 ? 138.903 161.781 178.128 1.00 67.28  0  159 ASP A OD1 1 
ATOM   1240 O  OD2 . ASP A 1 160 ? 139.776 163.213 176.718 1.00 67.28  -1 159 ASP A OD2 1 
ATOM   1241 N  N   . ILE A 1 161 ? 139.885 162.156 181.791 1.00 67.28  0  160 ILE A N   1 
ATOM   1242 C  CA  . ILE A 1 161 ? 139.674 161.036 182.703 1.00 67.28  0  160 ILE A CA  1 
ATOM   1243 C  C   . ILE A 1 161 ? 138.491 161.321 183.623 1.00 67.28  0  160 ILE A C   1 
ATOM   1244 O  O   . ILE A 1 161 ? 137.731 160.409 183.979 1.00 67.28  0  160 ILE A O   1 
ATOM   1245 C  CB  . ILE A 1 161 ? 140.965 160.741 183.492 1.00 67.28  0  160 ILE A CB  1 
ATOM   1246 C  CG1 . ILE A 1 161 ? 142.063 160.257 182.545 1.00 67.28  0  160 ILE A CG1 1 
ATOM   1247 C  CG2 . ILE A 1 161 ? 140.717 159.695 184.560 1.00 67.28  0  160 ILE A CG2 1 
ATOM   1248 C  CD1 . ILE A 1 161 ? 141.625 159.146 181.619 1.00 67.28  0  160 ILE A CD1 1 
ATOM   1249 N  N   . CYS A 1 162 ? 138.291 162.588 183.995 1.00 67.28  0  161 CYS A N   1 
ATOM   1250 C  CA  . CYS A 1 162 ? 137.179 162.944 184.872 1.00 67.28  0  161 CYS A CA  1 
ATOM   1251 C  C   . CYS A 1 162 ? 135.830 162.728 184.189 1.00 67.28  0  161 CYS A C   1 
ATOM   1252 O  O   . CYS A 1 162 ? 134.911 162.151 184.783 1.00 67.28  0  161 CYS A O   1 
ATOM   1253 C  CB  . CYS A 1 162 ? 137.322 164.393 185.336 1.00 67.28  0  161 CYS A CB  1 
ATOM   1254 S  SG  . CYS A 1 162 ? 138.583 164.647 186.605 1.00 67.28  0  161 CYS A SG  1 
ATOM   1255 N  N   . ASN A 1 163 ? 135.681 163.191 182.942 1.00 67.28  0  162 ASN A N   1 
ATOM   1256 C  CA  . ASN A 1 163 ? 134.429 162.944 182.236 1.00 67.28  0  162 ASN A CA  1 
ATOM   1257 C  C   . ASN A 1 163 ? 134.260 161.474 181.872 1.00 67.28  0  162 ASN A C   1 
ATOM   1258 O  O   . ASN A 1 163 ? 133.123 161.015 181.721 1.00 67.28  0  162 ASN A O   1 
ATOM   1259 C  CB  . ASN A 1 163 ? 134.318 163.846 180.996 1.00 67.28  0  162 ASN A CB  1 
ATOM   1260 C  CG  . ASN A 1 163 ? 135.346 163.527 179.915 1.00 67.28  0  162 ASN A CG  1 
ATOM   1261 O  OD1 . ASN A 1 163 ? 135.566 162.371 179.553 1.00 67.28  0  162 ASN A OD1 1 
ATOM   1262 N  ND2 . ASN A 1 163 ? 135.977 164.571 179.388 1.00 67.28  0  162 ASN A ND2 1 
ATOM   1263 N  N   . ALA A 1 164 ? 135.360 160.727 181.728 1.00 67.28  0  163 ALA A N   1 
ATOM   1264 C  CA  . ALA A 1 164 ? 135.249 159.279 181.589 1.00 67.28  0  163 ALA A CA  1 
ATOM   1265 C  C   . ALA A 1 164 ? 134.671 158.656 182.852 1.00 67.28  0  163 ALA A C   1 
ATOM   1266 O  O   . ALA A 1 164 ? 133.839 157.743 182.780 1.00 67.28  0  163 ALA A O   1 
ATOM   1267 C  CB  . ALA A 1 164 ? 136.615 158.674 181.267 1.00 67.28  0  163 ALA A CB  1 
ATOM   1268 N  N   . MET A 1 165 ? 135.108 159.135 184.018 1.00 67.28  0  164 MET A N   1 
ATOM   1269 C  CA  . MET A 1 165 ? 134.531 158.671 185.276 1.00 67.28  0  164 MET A CA  1 
ATOM   1270 C  C   . MET A 1 165 ? 133.066 159.071 185.410 1.00 67.28  0  164 MET A C   1 
ATOM   1271 O  O   . MET A 1 165 ? 132.261 158.301 185.946 1.00 67.28  0  164 MET A O   1 
ATOM   1272 C  CB  . MET A 1 165 ? 135.332 159.222 186.456 1.00 67.28  0  164 MET A CB  1 
ATOM   1273 C  CG  . MET A 1 165 ? 134.879 158.706 187.815 1.00 67.28  0  164 MET A CG  1 
ATOM   1274 S  SD  . MET A 1 165 ? 135.082 156.934 188.044 1.00 67.28  0  164 MET A SD  1 
ATOM   1275 C  CE  . MET A 1 165 ? 136.859 156.831 188.210 1.00 67.28  0  164 MET A CE  1 
ATOM   1276 N  N   . ALA A 1 166 ? 132.707 160.266 184.941 1.00 67.28  0  165 ALA A N   1 
ATOM   1277 C  CA  . ALA A 1 166 ? 131.355 160.786 185.125 1.00 67.28  0  165 ALA A CA  1 
ATOM   1278 C  C   . ALA A 1 166 ? 130.292 160.024 184.338 1.00 67.28  0  165 ALA A C   1 
ATOM   1279 O  O   . ALA A 1 166 ? 129.105 160.164 184.652 1.00 67.28  0  165 ALA A O   1 
ATOM   1280 C  CB  . ALA A 1 166 ? 131.307 162.267 184.741 1.00 67.28  0  165 ALA A CB  1 
ATOM   1281 N  N   . CYS A 1 167 ? 130.669 159.227 183.340 1.00 67.28  0  166 CYS A N   1 
ATOM   1282 C  CA  . CYS A 1 167 ? 129.708 158.551 182.469 1.00 67.28  0  166 CYS A CA  1 
ATOM   1283 C  C   . CYS A 1 167 ? 130.086 157.084 182.273 1.00 67.28  0  166 CYS A C   1 
ATOM   1284 O  O   . CYS A 1 167 ? 130.142 156.573 181.153 1.00 67.28  0  166 CYS A O   1 
ATOM   1285 C  CB  . CYS A 1 167 ? 129.583 159.274 181.128 1.00 67.28  0  166 CYS A CB  1 
ATOM   1286 S  SG  . CYS A 1 167 ? 131.073 159.292 180.101 1.00 67.28  0  166 CYS A SG  1 
ATOM   1287 N  N   . LEU A 1 168 ? 130.343 156.384 183.376 1.00 67.28  0  167 LEU A N   1 
ATOM   1288 C  CA  . LEU A 1 168 ? 130.721 154.978 183.304 1.00 67.28  0  167 LEU A CA  1 
ATOM   1289 C  C   . LEU A 1 168 ? 129.603 154.142 182.687 1.00 67.28  0  167 LEU A C   1 
ATOM   1290 O  O   . LEU A 1 168 ? 128.414 154.415 182.875 1.00 67.28  0  167 LEU A O   1 
ATOM   1291 C  CB  . LEU A 1 168 ? 131.057 154.449 184.696 1.00 67.28  0  167 LEU A CB  1 
ATOM   1292 C  CG  . LEU A 1 168 ? 132.292 155.053 185.364 1.00 67.28  0  167 LEU A CG  1 
ATOM   1293 C  CD1 . LEU A 1 168 ? 132.422 154.541 186.784 1.00 67.28  0  167 LEU A CD1 1 
ATOM   1294 C  CD2 . LEU A 1 168 ? 133.551 154.751 184.568 1.00 67.28  0  167 LEU A CD2 1 
ATOM   1295 N  N   . GLY A 1 169 ? 129.999 153.108 181.944 1.00 67.28  0  168 GLY A N   1 
ATOM   1296 C  CA  . GLY A 1 169 ? 129.073 152.253 181.224 1.00 67.28  0  168 GLY A CA  1 
ATOM   1297 C  C   . GLY A 1 169 ? 129.361 150.784 181.479 1.00 67.28  0  168 GLY A C   1 
ATOM   1298 O  O   . GLY A 1 169 ? 129.750 150.381 182.574 1.00 67.28  0  168 GLY A O   1 
ATOM   1299 N  N   . GLU A 1 170 ? 129.160 149.975 180.440 1.00 67.28  0  169 GLU A N   1 
ATOM   1300 C  CA  . GLU A 1 170 ? 129.298 148.530 180.520 1.00 67.28  0  169 GLU A CA  1 
ATOM   1301 C  C   . GLU A 1 170 ? 130.154 148.012 179.372 1.00 67.28  0  169 GLU A C   1 
ATOM   1302 O  O   . GLU A 1 170 ? 130.212 148.635 178.307 1.00 67.28  0  169 GLU A O   1 
ATOM   1303 C  CB  . GLU A 1 170 ? 127.924 147.843 180.478 1.00 67.28  0  169 GLU A CB  1 
ATOM   1304 C  CG  . GLU A 1 170 ? 126.902 148.415 181.449 1.00 67.28  0  169 GLU A CG  1 
ATOM   1305 C  CD  . GLU A 1 170 ? 126.997 147.806 182.834 1.00 67.28  0  169 GLU A CD  1 
ATOM   1306 O  OE1 . GLU A 1 170 ? 128.126 147.583 183.318 1.00 67.28  0  169 GLU A OE1 1 
ATOM   1307 O  OE2 . GLU A 1 170 ? 125.937 147.552 183.442 1.00 67.28  -1 169 GLU A OE2 1 
ATOM   1308 N  N   . PRO A 1 171 ? 130.831 146.881 179.562 1.00 67.28  0  170 PRO A N   1 
ATOM   1309 C  CA  . PRO A 1 171 ? 131.598 146.281 178.462 1.00 67.28  0  170 PRO A CA  1 
ATOM   1310 C  C   . PRO A 1 171 ? 130.674 145.672 177.416 1.00 67.28  0  170 PRO A C   1 
ATOM   1311 O  O   . PRO A 1 171 ? 129.479 145.469 177.640 1.00 67.28  0  170 PRO A O   1 
ATOM   1312 C  CB  . PRO A 1 171 ? 132.445 145.209 179.152 1.00 67.28  0  170 PRO A CB  1 
ATOM   1313 C  CG  . PRO A 1 171 ? 131.721 144.906 180.416 1.00 67.28  0  170 PRO A CG  1 
ATOM   1314 C  CD  . PRO A 1 171 ? 131.043 146.174 180.836 1.00 67.28  0  170 PRO A CD  1 
ATOM   1315 N  N   . ASP A 1 172 ? 131.248 145.376 176.250 1.00 67.28  0  171 ASP A N   1 
ATOM   1316 C  CA  . ASP A 1 172 ? 130.478 144.888 175.105 1.00 67.28  0  171 ASP A CA  1 
ATOM   1317 C  C   . ASP A 1 172 ? 130.893 143.447 174.806 1.00 67.28  0  171 ASP A C   1 
ATOM   1318 O  O   . ASP A 1 172 ? 131.939 143.191 174.188 1.00 67.28  0  171 ASP A O   1 
ATOM   1319 C  CB  . ASP A 1 172 ? 130.662 145.798 173.893 1.00 67.28  0  171 ASP A CB  1 
ATOM   1320 C  CG  . ASP A 1 172 ? 129.717 145.453 172.755 1.00 67.28  0  171 ASP A CG  1 
ATOM   1321 O  OD1 . ASP A 1 172 ? 128.939 144.486 172.891 1.00 67.28  0  171 ASP A OD1 1 
ATOM   1322 O  OD2 . ASP A 1 172 ? 129.728 146.171 171.733 1.00 67.28  -1 171 ASP A OD2 1 
ATOM   1323 N  N   . HIS A 1 173 ? 130.047 142.510 175.241 1.00 67.28  0  172 HIS A N   1 
ATOM   1324 C  CA  . HIS A 1 173 ? 130.293 141.099 174.977 1.00 67.28  0  172 HIS A CA  1 
ATOM   1325 C  C   . HIS A 1 173 ? 130.303 140.804 173.486 1.00 67.28  0  172 HIS A C   1 
ATOM   1326 O  O   . HIS A 1 173 ? 130.959 139.856 173.051 1.00 67.28  0  172 HIS A O   1 
ATOM   1327 C  CB  . HIS A 1 173 ? 129.244 140.242 175.683 1.00 67.28  0  172 HIS A CB  1 
ATOM   1328 C  CG  . HIS A 1 173 ? 129.746 138.894 176.096 1.00 67.28  0  172 HIS A CG  1 
ATOM   1329 N  ND1 . HIS A 1 173 ? 129.070 138.089 176.988 1.00 67.28  0  172 HIS A ND1 1 
ATOM   1330 C  CD2 . HIS A 1 173 ? 130.859 138.211 175.742 1.00 67.28  0  172 HIS A CD2 1 
ATOM   1331 C  CE1 . HIS A 1 173 ? 129.745 136.967 177.163 1.00 67.28  0  172 HIS A CE1 1 
ATOM   1332 N  NE2 . HIS A 1 173 ? 130.835 137.016 176.419 1.00 67.28  0  172 HIS A NE2 1 
ATOM   1333 N  N   . ASN A 1 174 ? 129.590 141.601 172.687 1.00 67.28  0  173 ASN A N   1 
ATOM   1334 C  CA  . ASN A 1 174 ? 129.626 141.406 171.242 1.00 67.28  0  173 ASN A CA  1 
ATOM   1335 C  C   . ASN A 1 174 ? 131.018 141.675 170.681 1.00 67.28  0  173 ASN A C   1 
ATOM   1336 O  O   . ASN A 1 174 ? 131.525 140.896 169.865 1.00 67.28  0  173 ASN A O   1 
ATOM   1337 C  CB  . ASN A 1 174 ? 128.585 142.300 170.571 1.00 67.28  0  173 ASN A CB  1 
ATOM   1338 C  CG  . ASN A 1 174 ? 127.181 142.038 171.081 1.00 67.28  0  173 ASN A CG  1 
ATOM   1339 O  OD1 . ASN A 1 174 ? 126.881 140.951 171.573 1.00 67.28  0  173 ASN A OD1 1 
ATOM   1340 N  ND2 . ASN A 1 174 ? 126.315 143.038 170.971 1.00 67.28  0  173 ASN A ND2 1 
ATOM   1341 N  N   . GLU A 1 175 ? 131.659 142.763 171.117 1.00 67.28  0  174 GLU A N   1 
ATOM   1342 C  CA  . GLU A 1 175 ? 133.031 143.030 170.694 1.00 67.28  0  174 GLU A CA  1 
ATOM   1343 C  C   . GLU A 1 175 ? 133.988 141.966 171.217 1.00 67.28  0  174 GLU A C   1 
ATOM   1344 O  O   . GLU A 1 175 ? 134.899 141.529 170.496 1.00 67.28  0  174 GLU A O   1 
ATOM   1345 C  CB  . GLU A 1 175 ? 133.464 144.420 171.159 1.00 67.28  0  174 GLU A CB  1 
ATOM   1346 C  CG  . GLU A 1 175 ? 132.568 145.541 170.666 1.00 67.28  0  174 GLU A CG  1 
ATOM   1347 C  CD  . GLU A 1 175 ? 133.224 146.904 170.759 1.00 67.28  0  174 GLU A CD  1 
ATOM   1348 O  OE1 . GLU A 1 175 ? 133.619 147.300 171.875 1.00 67.28  0  174 GLU A OE1 1 
ATOM   1349 O  OE2 . GLU A 1 175 ? 133.343 147.582 169.716 1.00 67.28  -1 174 GLU A OE2 1 
ATOM   1350 N  N   . ALA A 1 176 ? 133.798 141.537 172.468 1.00 67.28  0  175 ALA A N   1 
ATOM   1351 C  CA  . ALA A 1 176 ? 134.647 140.477 173.003 1.00 67.28  0  175 ALA A CA  1 
ATOM   1352 C  C   . ALA A 1 176 ? 134.526 139.202 172.175 1.00 67.28  0  175 ALA A C   1 
ATOM   1353 O  O   . ALA A 1 176 ? 135.534 138.558 171.854 1.00 67.28  0  175 ALA A O   1 
ATOM   1354 C  CB  . ALA A 1 176 ? 134.291 140.203 174.463 1.00 67.28  0  175 ALA A CB  1 
ATOM   1355 N  N   . LEU A 1 177 ? 133.299 138.834 171.803 1.00 67.28  0  176 LEU A N   1 
ATOM   1356 C  CA  . LEU A 1 177 ? 133.084 137.637 171.001 1.00 67.28  0  176 LEU A CA  1 
ATOM   1357 C  C   . LEU A 1 177 ? 133.627 137.800 169.590 1.00 67.28  0  176 LEU A C   1 
ATOM   1358 O  O   . LEU A 1 177 ? 134.093 136.824 169.000 1.00 67.28  0  176 LEU A O   1 
ATOM   1359 C  CB  . LEU A 1 177 ? 131.596 137.291 170.962 1.00 67.28  0  176 LEU A CB  1 
ATOM   1360 C  CG  . LEU A 1 177 ? 131.005 136.707 172.246 1.00 67.28  0  176 LEU A CG  1 
ATOM   1361 C  CD1 . LEU A 1 177 ? 129.637 136.101 171.979 1.00 67.28  0  176 LEU A CD1 1 
ATOM   1362 C  CD2 . LEU A 1 177 ? 131.942 135.676 172.853 1.00 67.28  0  176 LEU A CD2 1 
ATOM   1363 N  N   . SER A 1 178 ? 133.572 139.010 169.030 1.00 67.28  0  177 SER A N   1 
ATOM   1364 C  CA  . SER A 1 178 ? 134.182 139.242 167.724 1.00 67.28  0  177 SER A CA  1 
ATOM   1365 C  C   . SER A 1 178 ? 135.686 139.000 167.774 1.00 67.28  0  177 SER A C   1 
ATOM   1366 O  O   . SER A 1 178 ? 136.254 138.328 166.900 1.00 67.28  0  177 SER A O   1 
ATOM   1367 C  CB  . SER A 1 178 ? 133.880 140.663 167.249 1.00 67.28  0  177 SER A CB  1 
ATOM   1368 O  OG  . SER A 1 178 ? 134.821 141.085 166.279 1.00 67.28  0  177 SER A OG  1 
ATOM   1369 N  N   . VAL A 1 179 ? 136.347 139.534 168.805 1.00 67.28  0  178 VAL A N   1 
ATOM   1370 C  CA  . VAL A 1 179 ? 137.786 139.320 168.947 1.00 67.28  0  178 VAL A CA  1 
ATOM   1371 C  C   . VAL A 1 179 ? 138.090 137.838 169.133 1.00 67.28  0  178 VAL A C   1 
ATOM   1372 O  O   . VAL A 1 179 ? 139.022 137.294 168.522 1.00 67.28  0  178 VAL A O   1 
ATOM   1373 C  CB  . VAL A 1 179 ? 138.342 140.164 170.109 1.00 67.28  0  178 VAL A CB  1 
ATOM   1374 C  CG1 . VAL A 1 179 ? 139.825 139.897 170.295 1.00 67.28  0  178 VAL A CG1 1 
ATOM   1375 C  CG2 . VAL A 1 179 ? 138.094 141.641 169.856 1.00 67.28  0  178 VAL A CG2 1 
ATOM   1376 N  N   . ASP A 1 180 ? 137.303 137.160 169.974 1.00 67.28  0  179 ASP A N   1 
ATOM   1377 C  CA  . ASP A 1 180 ? 137.520 135.735 170.206 1.00 67.28  0  179 ASP A CA  1 
ATOM   1378 C  C   . ASP A 1 180 ? 137.318 134.927 168.930 1.00 67.28  0  179 ASP A C   1 
ATOM   1379 O  O   . ASP A 1 180 ? 138.070 133.984 168.658 1.00 67.28  0  179 ASP A O   1 
ATOM   1380 C  CB  . ASP A 1 180 ? 136.586 135.238 171.310 1.00 67.28  0  179 ASP A CB  1 
ATOM   1381 C  CG  . ASP A 1 180 ? 137.239 135.257 172.677 1.00 67.28  0  179 ASP A CG  1 
ATOM   1382 O  OD1 . ASP A 1 180 ? 138.485 135.278 172.742 1.00 67.28  0  179 ASP A OD1 1 
ATOM   1383 O  OD2 . ASP A 1 180 ? 136.505 135.250 173.687 1.00 67.28  -1 179 ASP A OD2 1 
ATOM   1384 N  N   . ALA A 1 181 ? 136.299 135.275 168.141 1.00 67.28  0  180 ALA A N   1 
ATOM   1385 C  CA  . ALA A 1 181 ? 136.047 134.575 166.887 1.00 67.28  0  180 ALA A CA  1 
ATOM   1386 C  C   . ALA A 1 181 ? 137.197 134.761 165.912 1.00 67.28  0  180 ALA A C   1 
ATOM   1387 O  O   . ALA A 1 181 ? 137.617 133.805 165.249 1.00 67.28  0  180 ALA A O   1 
ATOM   1388 C  CB  . ALA A 1 181 ? 134.740 135.063 166.267 1.00 67.28  0  180 ALA A CB  1 
ATOM   1389 N  N   . ARG A 1 182 ? 137.720 135.985 165.805 1.00 67.28  0  181 ARG A N   1 
ATOM   1390 C  CA  . ARG A 1 182 ? 138.868 136.210 164.933 1.00 67.28  0  181 ARG A CA  1 
ATOM   1391 C  C   . ARG A 1 182 ? 140.060 135.371 165.376 1.00 67.28  0  181 ARG A C   1 
ATOM   1392 O  O   . ARG A 1 182 ? 140.716 134.711 164.555 1.00 67.28  0  181 ARG A O   1 
ATOM   1393 C  CB  . ARG A 1 182 ? 139.235 137.694 164.916 1.00 67.28  0  181 ARG A CB  1 
ATOM   1394 C  CG  . ARG A 1 182 ? 140.102 138.100 163.738 1.00 67.28  0  181 ARG A CG  1 
ATOM   1395 C  CD  . ARG A 1 182 ? 140.774 139.441 163.981 1.00 67.28  0  181 ARG A CD  1 
ATOM   1396 N  NE  . ARG A 1 182 ? 141.621 139.420 165.168 1.00 67.28  0  181 ARG A NE  1 
ATOM   1397 C  CZ  . ARG A 1 182 ? 141.718 140.418 166.035 1.00 67.28  0  181 ARG A CZ  1 
ATOM   1398 N  NH1 . ARG A 1 182 ? 141.029 141.537 165.882 1.00 67.28  1  181 ARG A NH1 1 
ATOM   1399 N  NH2 . ARG A 1 182 ? 142.528 140.291 167.082 1.00 67.28  0  181 ARG A NH2 1 
ATOM   1400 N  N   . GLN A 1 183 ? 140.344 135.374 166.683 1.00 67.28  0  182 GLN A N   1 
ATOM   1401 C  CA  . GLN A 1 183 ? 141.478 134.610 167.192 1.00 67.28  0  182 GLN A CA  1 
ATOM   1402 C  C   . GLN A 1 183 ? 141.311 133.123 166.913 1.00 67.28  0  182 GLN A C   1 
ATOM   1403 O  O   . GLN A 1 183 ? 142.255 132.457 166.470 1.00 67.28  0  182 GLN A O   1 
ATOM   1404 C  CB  . GLN A 1 183 ? 141.649 134.854 168.691 1.00 67.28  0  182 GLN A CB  1 
ATOM   1405 C  CG  . GLN A 1 183 ? 142.049 136.271 169.053 1.00 67.28  0  182 GLN A CG  1 
ATOM   1406 C  CD  . GLN A 1 183 ? 142.607 136.373 170.457 1.00 67.28  0  182 GLN A CD  1 
ATOM   1407 O  OE1 . GLN A 1 183 ? 142.143 135.693 171.371 1.00 67.28  0  182 GLN A OE1 1 
ATOM   1408 N  NE2 . GLN A 1 183 ? 143.607 137.228 170.636 1.00 67.28  0  182 GLN A NE2 1 
ATOM   1409 N  N   . GLU A 1 184 ? 140.113 132.586 167.159 1.00 67.28  0  183 GLU A N   1 
ATOM   1410 C  CA  . GLU A 1 184 ? 139.868 131.169 166.919 1.00 67.28  0  183 GLU A CA  1 
ATOM   1411 C  C   . GLU A 1 184 ? 140.004 130.826 165.442 1.00 67.28  0  183 GLU A C   1 
ATOM   1412 O  O   . GLU A 1 184 ? 140.612 129.808 165.087 1.00 67.28  0  183 GLU A O   1 
ATOM   1413 C  CB  . GLU A 1 184 ? 138.481 130.784 167.431 1.00 67.28  0  183 GLU A CB  1 
ATOM   1414 C  CG  . GLU A 1 184 ? 138.096 129.341 167.160 1.00 67.28  0  183 GLU A CG  1 
ATOM   1415 C  CD  . GLU A 1 184 ? 137.182 128.768 168.224 1.00 67.28  0  183 GLU A CD  1 
ATOM   1416 O  OE1 . GLU A 1 184 ? 136.692 129.544 169.071 1.00 67.28  0  183 GLU A OE1 1 
ATOM   1417 O  OE2 . GLU A 1 184 ? 136.952 127.541 168.212 1.00 67.28  -1 183 GLU A OE2 1 
ATOM   1418 N  N   . LEU A 1 185 ? 139.454 131.668 164.565 1.00 67.28  0  184 LEU A N   1 
ATOM   1419 C  CA  . LEU A 1 185 ? 139.518 131.396 163.134 1.00 67.28  0  184 LEU A CA  1 
ATOM   1420 C  C   . LEU A 1 185 ? 140.959 131.350 162.648 1.00 67.28  0  184 LEU A C   1 
ATOM   1421 O  O   . LEU A 1 185 ? 141.353 130.426 161.922 1.00 67.28  0  184 LEU A O   1 
ATOM   1422 C  CB  . LEU A 1 185 ? 138.723 132.451 162.365 1.00 67.28  0  184 LEU A CB  1 
ATOM   1423 C  CG  . LEU A 1 185 ? 137.262 132.117 162.071 1.00 67.28  0  184 LEU A CG  1 
ATOM   1424 C  CD1 . LEU A 1 185 ? 136.660 133.153 161.140 1.00 67.28  0  184 LEU A CD1 1 
ATOM   1425 C  CD2 . LEU A 1 185 ? 137.137 130.721 161.481 1.00 67.28  0  184 LEU A CD2 1 
ATOM   1426 N  N   . ASP A 1 186 ? 141.768 132.340 163.039 1.00 67.28  0  185 ASP A N   1 
ATOM   1427 C  CA  . ASP A 1 186 ? 143.174 132.311 162.644 1.00 67.28  0  185 ASP A CA  1 
ATOM   1428 C  C   . ASP A 1 186 ? 143.881 131.092 163.226 1.00 67.28  0  185 ASP A C   1 
ATOM   1429 O  O   . ASP A 1 186 ? 144.493 130.306 162.490 1.00 67.28  0  185 ASP A O   1 
ATOM   1430 C  CB  . ASP A 1 186 ? 143.886 133.601 163.060 1.00 67.28  0  185 ASP A CB  1 
ATOM   1431 C  CG  . ASP A 1 186 ? 143.181 134.849 162.564 1.00 67.28  0  185 ASP A CG  1 
ATOM   1432 O  OD1 . ASP A 1 186 ? 142.970 134.962 161.338 1.00 67.28  0  185 ASP A OD1 1 
ATOM   1433 O  OD2 . ASP A 1 186 ? 142.876 135.736 163.388 1.00 67.28  -1 185 ASP A OD2 1 
ATOM   1434 N  N   . LEU A 1 187 ? 143.766 130.893 164.544 1.00 67.28  0  186 LEU A N   1 
ATOM   1435 C  CA  . LEU A 1 187 ? 144.481 129.811 165.213 1.00 67.28  0  186 LEU A CA  1 
ATOM   1436 C  C   . LEU A 1 187 ? 144.091 128.444 164.671 1.00 67.28  0  186 LEU A C   1 
ATOM   1437 O  O   . LEU A 1 187 ? 144.858 127.485 164.802 1.00 67.28  0  186 LEU A O   1 
ATOM   1438 C  CB  . LEU A 1 187 ? 144.218 129.871 166.716 1.00 67.28  0  186 LEU A CB  1 
ATOM   1439 C  CG  . LEU A 1 187 ? 144.930 128.853 167.606 1.00 67.28  0  186 LEU A CG  1 
ATOM   1440 C  CD1 . LEU A 1 187 ? 146.439 129.027 167.538 1.00 67.28  0  186 LEU A CD1 1 
ATOM   1441 C  CD2 . LEU A 1 187 ? 144.432 128.969 169.030 1.00 67.28  0  186 LEU A CD2 1 
ATOM   1442 N  N   . ARG A 1 188 ? 142.909 128.324 164.074 1.00 67.28  0  187 ARG A N   1 
ATOM   1443 C  CA  . ARG A 1 188 ? 142.521 127.046 163.493 1.00 67.28  0  187 ARG A CA  1 
ATOM   1444 C  C   . ARG A 1 188 ? 143.007 126.919 162.052 1.00 67.28  0  187 ARG A C   1 
ATOM   1445 O  O   . ARG A 1 188 ? 143.771 126.003 161.730 1.00 67.28  0  187 ARG A O   1 
ATOM   1446 C  CB  . ARG A 1 188 ? 141.002 126.870 163.586 1.00 67.28  0  187 ARG A CB  1 
ATOM   1447 C  CG  . ARG A 1 188 ? 140.535 126.408 164.957 1.00 67.28  0  187 ARG A CG  1 
ATOM   1448 C  CD  . ARG A 1 188 ? 139.051 126.108 164.971 1.00 67.28  0  187 ARG A CD  1 
ATOM   1449 N  NE  . ARG A 1 188 ? 138.531 125.980 166.327 1.00 67.28  0  187 ARG A NE  1 
ATOM   1450 C  CZ  . ARG A 1 188 ? 138.689 124.910 167.093 1.00 67.28  0  187 ARG A CZ  1 
ATOM   1451 N  NH1 . ARG A 1 188 ? 139.348 123.845 166.668 1.00 67.28  1  187 ARG A NH1 1 
ATOM   1452 N  NH2 . ARG A 1 188 ? 138.169 124.906 168.317 1.00 67.28  0  187 ARG A NH2 1 
ATOM   1453 N  N   . ILE A 1 189 ? 142.594 127.845 161.182 1.00 67.28  0  188 ILE A N   1 
ATOM   1454 C  CA  . ILE A 1 189 ? 142.878 127.701 159.755 1.00 67.28  0  188 ILE A CA  1 
ATOM   1455 C  C   . ILE A 1 189 ? 144.378 127.767 159.491 1.00 67.28  0  188 ILE A C   1 
ATOM   1456 O  O   . ILE A 1 189 ? 144.951 126.895 158.817 1.00 67.28  0  188 ILE A O   1 
ATOM   1457 C  CB  . ILE A 1 189 ? 142.120 128.773 158.953 1.00 67.28  0  188 ILE A CB  1 
ATOM   1458 C  CG1 . ILE A 1 189 ? 140.625 128.713 159.270 1.00 67.28  0  188 ILE A CG1 1 
ATOM   1459 C  CG2 . ILE A 1 189 ? 142.366 128.597 157.465 1.00 67.28  0  188 ILE A CG2 1 
ATOM   1460 C  CD1 . ILE A 1 189 ? 139.881 129.983 158.936 1.00 67.28  0  188 ILE A CD1 1 
ATOM   1461 N  N   . GLY A 1 190 ? 145.038 128.808 160.009 1.00 67.28  0  189 GLY A N   1 
ATOM   1462 C  CA  . GLY A 1 190 ? 146.450 128.980 159.722 1.00 67.28  0  189 GLY A CA  1 
ATOM   1463 C  C   . GLY A 1 190 ? 147.292 127.852 160.278 1.00 67.28  0  189 GLY A C   1 
ATOM   1464 O  O   . GLY A 1 190 ? 148.191 127.347 159.602 1.00 67.28  0  189 GLY A O   1 
ATOM   1465 N  N   . CYS A 1 191 ? 147.008 127.435 161.513 1.00 67.28  0  190 CYS A N   1 
ATOM   1466 C  CA  . CYS A 1 191 ? 147.769 126.342 162.106 1.00 67.28  0  190 CYS A CA  1 
ATOM   1467 C  C   . CYS A 1 191 ? 147.533 125.034 161.366 1.00 67.28  0  190 CYS A C   1 
ATOM   1468 O  O   . CYS A 1 191 ? 148.474 124.261 161.168 1.00 67.28  0  190 CYS A O   1 
ATOM   1469 C  CB  . CYS A 1 191 ? 147.434 126.198 163.588 1.00 67.28  0  190 CYS A CB  1 
ATOM   1470 S  SG  . CYS A 1 191 ? 147.946 127.611 164.593 1.00 67.28  0  190 CYS A SG  1 
ATOM   1471 N  N   . ALA A 1 192 ? 146.298 124.767 160.932 1.00 67.28  0  191 ALA A N   1 
ATOM   1472 C  CA  . ALA A 1 192 ? 146.041 123.543 160.181 1.00 67.28  0  191 ALA A CA  1 
ATOM   1473 C  C   . ALA A 1 192 ? 146.844 123.513 158.886 1.00 67.28  0  191 ALA A C   1 
ATOM   1474 O  O   . ALA A 1 192 ? 147.566 122.543 158.608 1.00 67.28  0  191 ALA A O   1 
ATOM   1475 C  CB  . ALA A 1 192 ? 144.546 123.409 159.893 1.00 67.28  0  191 ALA A CB  1 
ATOM   1476 N  N   . PHE A 1 193 ? 146.744 124.580 158.085 1.00 67.28  0  192 PHE A N   1 
ATOM   1477 C  CA  . PHE A 1 193 ? 147.470 124.603 156.817 1.00 67.28  0  192 PHE A CA  1 
ATOM   1478 C  C   . PHE A 1 193 ? 148.979 124.555 157.036 1.00 67.28  0  192 PHE A C   1 
ATOM   1479 O  O   . PHE A 1 193 ? 149.693 123.820 156.339 1.00 67.28  0  192 PHE A O   1 
ATOM   1480 C  CB  . PHE A 1 193 ? 147.083 125.838 156.005 1.00 67.28  0  192 PHE A CB  1 
ATOM   1481 C  CG  . PHE A 1 193 ? 145.780 125.701 155.270 1.00 67.28  0  192 PHE A CG  1 
ATOM   1482 C  CD1 . PHE A 1 193 ? 144.583 126.022 155.885 1.00 67.28  0  192 PHE A CD1 1 
ATOM   1483 C  CD2 . PHE A 1 193 ? 145.755 125.260 153.960 1.00 67.28  0  192 PHE A CD2 1 
ATOM   1484 C  CE1 . PHE A 1 193 ? 143.386 125.899 155.208 1.00 67.28  0  192 PHE A CE1 1 
ATOM   1485 C  CE2 . PHE A 1 193 ? 144.561 125.136 153.279 1.00 67.28  0  192 PHE A CE2 1 
ATOM   1486 C  CZ  . PHE A 1 193 ? 143.376 125.455 153.904 1.00 67.28  0  192 PHE A CZ  1 
ATOM   1487 N  N   . THR A 1 194 ? 149.483 125.328 158.003 1.00 67.28  0  193 THR A N   1 
ATOM   1488 C  CA  . THR A 1 194 ? 150.917 125.366 158.257 1.00 67.28  0  193 THR A CA  1 
ATOM   1489 C  C   . THR A 1 194 ? 151.432 124.016 158.735 1.00 67.28  0  193 THR A C   1 
ATOM   1490 O  O   . THR A 1 194 ? 152.500 123.568 158.307 1.00 67.28  0  193 THR A O   1 
ATOM   1491 C  CB  . THR A 1 194 ? 151.237 126.455 159.282 1.00 67.28  0  193 THR A CB  1 
ATOM   1492 O  OG1 . THR A 1 194 ? 150.802 127.725 158.781 1.00 67.28  0  193 THR A OG1 1 
ATOM   1493 C  CG2 . THR A 1 194 ? 152.732 126.511 159.555 1.00 67.28  0  193 THR A CG2 1 
ATOM   1494 N  N   . ARG A 1 195 ? 150.690 123.352 159.626 1.00 67.28  0  194 ARG A N   1 
ATOM   1495 C  CA  . ARG A 1 195 ? 151.107 122.043 160.110 1.00 67.28  0  194 ARG A CA  1 
ATOM   1496 C  C   . ARG A 1 195 ? 151.125 121.023 158.982 1.00 67.28  0  194 ARG A C   1 
ATOM   1497 O  O   . ARG A 1 195 ? 152.065 120.225 158.872 1.00 67.28  0  194 ARG A O   1 
ATOM   1498 C  CB  . ARG A 1 195 ? 150.177 121.583 161.232 1.00 67.28  0  194 ARG A CB  1 
ATOM   1499 C  CG  . ARG A 1 195 ? 150.601 122.032 162.617 1.00 67.28  0  194 ARG A CG  1 
ATOM   1500 C  CD  . ARG A 1 195 ? 149.425 122.000 163.578 1.00 67.28  0  194 ARG A CD  1 
ATOM   1501 N  NE  . ARG A 1 195 ? 149.854 121.908 164.968 1.00 67.28  0  194 ARG A NE  1 
ATOM   1502 C  CZ  . ARG A 1 195 ? 150.249 122.941 165.698 1.00 67.28  0  194 ARG A CZ  1 
ATOM   1503 N  NH1 . ARG A 1 195 ? 150.279 124.167 165.202 1.00 67.28  1  194 ARG A NH1 1 
ATOM   1504 N  NH2 . ARG A 1 195 ? 150.622 122.740 166.959 1.00 67.28  0  194 ARG A NH2 1 
ATOM   1505 N  N   . PHE A 1 196 ? 150.098 121.036 158.126 1.00 67.28  0  195 PHE A N   1 
ATOM   1506 C  CA  . PHE A 1 196 ? 150.079 120.090 157.015 1.00 67.28  0  195 PHE A CA  1 
ATOM   1507 C  C   . PHE A 1 196 ? 151.253 120.322 156.073 1.00 67.28  0  195 PHE A C   1 
ATOM   1508 O  O   . PHE A 1 196 ? 151.922 119.368 155.656 1.00 67.28  0  195 PHE A O   1 
ATOM   1509 C  CB  . PHE A 1 196 ? 148.760 120.186 156.252 1.00 67.28  0  195 PHE A CB  1 
ATOM   1510 C  CG  . PHE A 1 196 ? 148.756 119.420 154.962 1.00 67.28  0  195 PHE A CG  1 
ATOM   1511 C  CD1 . PHE A 1 196 ? 149.065 118.071 154.944 1.00 67.28  0  195 PHE A CD1 1 
ATOM   1512 C  CD2 . PHE A 1 196 ? 148.452 120.048 153.768 1.00 67.28  0  195 PHE A CD2 1 
ATOM   1513 C  CE1 . PHE A 1 196 ? 149.066 117.362 153.761 1.00 67.28  0  195 PHE A CE1 1 
ATOM   1514 C  CE2 . PHE A 1 196 ? 148.451 119.344 152.582 1.00 67.28  0  195 PHE A CE2 1 
ATOM   1515 C  CZ  . PHE A 1 196 ? 148.759 117.999 152.579 1.00 67.28  0  195 PHE A CZ  1 
ATOM   1516 N  N   . GLN A 1 197 ? 151.528 121.585 155.736 1.00 67.28  0  196 GLN A N   1 
ATOM   1517 C  CA  . GLN A 1 197 ? 152.635 121.872 154.828 1.00 67.28  0  196 GLN A CA  1 
ATOM   1518 C  C   . GLN A 1 197 ? 153.980 121.538 155.463 1.00 67.28  0  196 GLN A C   1 
ATOM   1519 O  O   . GLN A 1 197 ? 154.887 121.045 154.783 1.00 67.28  0  196 GLN A O   1 
ATOM   1520 C  CB  . GLN A 1 197 ? 152.591 123.333 154.391 1.00 67.28  0  196 GLN A CB  1 
ATOM   1521 C  CG  . GLN A 1 197 ? 151.382 123.676 153.550 1.00 67.28  0  196 GLN A CG  1 
ATOM   1522 C  CD  . GLN A 1 197 ? 151.662 124.787 152.567 1.00 67.28  0  196 GLN A CD  1 
ATOM   1523 O  OE1 . GLN A 1 197 ? 151.011 125.829 152.594 1.00 67.28  0  196 GLN A OE1 1 
ATOM   1524 N  NE2 . GLN A 1 197 ? 152.635 124.572 151.691 1.00 67.28  0  196 GLN A NE2 1 
ATOM   1525 N  N   . THR A 1 198 ? 154.131 121.811 156.761 1.00 67.28  0  197 THR A N   1 
ATOM   1526 C  CA  . THR A 1 198 ? 155.369 121.481 157.457 1.00 67.28  0  197 THR A CA  1 
ATOM   1527 C  C   . THR A 1 198 ? 155.606 119.978 157.470 1.00 67.28  0  197 THR A C   1 
ATOM   1528 O  O   . THR A 1 198 ? 156.732 119.518 157.248 1.00 67.28  0  197 THR A O   1 
ATOM   1529 C  CB  . THR A 1 198 ? 155.325 122.034 158.883 1.00 67.28  0  197 THR A CB  1 
ATOM   1530 O  OG1 . THR A 1 198 ? 155.237 123.464 158.841 1.00 67.28  0  197 THR A OG1 1 
ATOM   1531 C  CG2 . THR A 1 198 ? 156.566 121.629 159.664 1.00 67.28  0  197 THR A CG2 1 
ATOM   1532 N  N   . LYS A 1 199 ? 154.556 119.195 157.725 1.00 67.28  0  198 LYS A N   1 
ATOM   1533 C  CA  . LYS A 1 199 ? 154.702 117.744 157.689 1.00 67.28  0  198 LYS A CA  1 
ATOM   1534 C  C   . LYS A 1 199 ? 155.023 117.254 156.282 1.00 67.28  0  198 LYS A C   1 
ATOM   1535 O  O   . LYS A 1 199 ? 155.858 116.359 156.108 1.00 67.28  0  198 LYS A O   1 
ATOM   1536 C  CB  . LYS A 1 199 ? 153.435 117.072 158.215 1.00 67.28  0  198 LYS A CB  1 
ATOM   1537 C  CG  . LYS A 1 199 ? 153.586 115.578 158.442 1.00 67.28  0  198 LYS A CG  1 
ATOM   1538 C  CD  . LYS A 1 199 ? 154.757 115.279 159.364 1.00 67.28  0  198 LYS A CD  1 
ATOM   1539 C  CE  . LYS A 1 199 ? 154.896 113.787 159.617 1.00 67.28  0  198 LYS A CE  1 
ATOM   1540 N  NZ  . LYS A 1 199 ? 154.538 112.986 158.414 1.00 67.28  1  198 LYS A NZ  1 
ATOM   1541 N  N   . TYR A 1 200 ? 154.367 117.821 155.266 1.00 67.28  0  199 TYR A N   1 
ATOM   1542 C  CA  . TYR A 1 200 ? 154.611 117.393 153.892 1.00 67.28  0  199 TYR A CA  1 
ATOM   1543 C  C   . TYR A 1 200 ? 156.044 117.695 153.467 1.00 67.28  0  199 TYR A C   1 
ATOM   1544 O  O   . TYR A 1 200 ? 156.826 116.784 153.174 1.00 67.28  0  199 TYR A O   1 
ATOM   1545 C  CB  . TYR A 1 200 ? 153.612 118.065 152.950 1.00 67.28  0  199 TYR A CB  1 
ATOM   1546 C  CG  . TYR A 1 200 ? 153.438 117.345 151.633 1.00 67.28  0  199 TYR A CG  1 
ATOM   1547 C  CD1 . TYR A 1 200 ? 152.491 116.341 151.489 1.00 67.28  0  199 TYR A CD1 1 
ATOM   1548 C  CD2 . TYR A 1 200 ? 154.221 117.667 150.535 1.00 67.28  0  199 TYR A CD2 1 
ATOM   1549 C  CE1 . TYR A 1 200 ? 152.328 115.679 150.288 1.00 67.28  0  199 TYR A CE1 1 
ATOM   1550 C  CE2 . TYR A 1 200 ? 154.065 117.011 149.330 1.00 67.28  0  199 TYR A CE2 1 
ATOM   1551 C  CZ  . TYR A 1 200 ? 153.118 116.018 149.212 1.00 67.28  0  199 TYR A CZ  1 
ATOM   1552 O  OH  . TYR A 1 200 ? 152.959 115.362 148.014 1.00 67.28  0  199 TYR A OH  1 
ATOM   1553 N  N   . PHE A 1 201 ? 156.405 118.976 153.425 1.00 67.28  0  200 PHE A N   1 
ATOM   1554 C  CA  . PHE A 1 201 ? 157.754 119.395 153.049 1.00 67.28  0  200 PHE A CA  1 
ATOM   1555 C  C   . PHE A 1 201 ? 158.623 119.383 154.300 1.00 67.28  0  200 PHE A C   1 
ATOM   1556 O  O   . PHE A 1 201 ? 158.594 120.321 155.099 1.00 67.28  0  200 PHE A O   1 
ATOM   1557 C  CB  . PHE A 1 201 ? 157.735 120.775 152.401 1.00 67.28  0  200 PHE A CB  1 
ATOM   1558 C  CG  . PHE A 1 201 ? 156.775 120.898 151.253 1.00 67.28  0  200 PHE A CG  1 
ATOM   1559 C  CD1 . PHE A 1 201 ? 156.903 120.090 150.138 1.00 67.28  0  200 PHE A CD1 1 
ATOM   1560 C  CD2 . PHE A 1 201 ? 155.749 121.825 151.288 1.00 67.28  0  200 PHE A CD2 1 
ATOM   1561 C  CE1 . PHE A 1 201 ? 156.025 120.205 149.080 1.00 67.28  0  200 PHE A CE1 1 
ATOM   1562 C  CE2 . PHE A 1 201 ? 154.868 121.943 150.233 1.00 67.28  0  200 PHE A CE2 1 
ATOM   1563 C  CZ  . PHE A 1 201 ? 155.006 121.131 149.129 1.00 67.28  0  200 PHE A CZ  1 
ATOM   1564 N  N   . GLN A 1 202 ? 159.397 118.314 154.474 1.00 67.28  0  201 GLN A N   1 
ATOM   1565 C  CA  . GLN A 1 202 ? 160.307 118.208 155.613 1.00 67.28  0  201 GLN A CA  1 
ATOM   1566 C  C   . GLN A 1 202 ? 161.444 117.283 155.206 1.00 67.28  0  201 GLN A C   1 
ATOM   1567 O  O   . GLN A 1 202 ? 161.267 116.061 155.181 1.00 67.28  0  201 GLN A O   1 
ATOM   1568 C  CB  . GLN A 1 202 ? 159.582 117.686 156.847 1.00 67.28  0  201 GLN A CB  1 
ATOM   1569 C  CG  . GLN A 1 202 ? 160.255 118.053 158.158 1.00 67.28  0  201 GLN A CG  1 
ATOM   1570 C  CD  . GLN A 1 202 ? 160.098 116.980 159.216 1.00 67.28  0  201 GLN A CD  1 
ATOM   1571 O  OE1 . GLN A 1 202 ? 160.179 115.787 158.923 1.00 67.28  0  201 GLN A OE1 1 
ATOM   1572 N  NE2 . GLN A 1 202 ? 159.874 117.399 160.455 1.00 67.28  0  201 GLN A NE2 1 
ATOM   1573 N  N   . GLY A 1 203 ? 162.600 117.862 154.889 1.00 67.28  0  202 GLY A N   1 
ATOM   1574 C  CA  . GLY A 1 203 ? 163.700 117.081 154.363 1.00 67.28  0  202 GLY A CA  1 
ATOM   1575 C  C   . GLY A 1 203 ? 163.502 116.598 152.948 1.00 67.28  0  202 GLY A C   1 
ATOM   1576 O  O   . GLY A 1 203 ? 164.323 115.821 152.451 1.00 67.28  0  202 GLY A O   1 
ATOM   1577 N  N   . LYS A 1 204 ? 162.430 117.032 152.283 1.00 67.28  0  203 LYS A N   1 
ATOM   1578 C  CA  . LYS A 1 204 ? 162.184 116.616 150.908 1.00 67.28  0  203 LYS A CA  1 
ATOM   1579 C  C   . LYS A 1 204 ? 163.126 117.322 149.942 1.00 67.28  0  203 LYS A C   1 
ATOM   1580 O  O   . LYS A 1 204 ? 163.628 116.708 148.993 1.00 67.28  0  203 LYS A O   1 
ATOM   1581 C  CB  . LYS A 1 204 ? 160.727 116.891 150.538 1.00 67.28  0  203 LYS A CB  1 
ATOM   1582 C  CG  . LYS A 1 204 ? 160.209 116.092 149.357 1.00 67.28  0  203 LYS A CG  1 
ATOM   1583 C  CD  . LYS A 1 204 ? 158.696 115.947 149.425 1.00 67.28  0  203 LYS A CD  1 
ATOM   1584 C  CE  . LYS A 1 204 ? 158.071 115.970 148.042 1.00 67.28  0  203 LYS A CE  1 
ATOM   1585 N  NZ  . LYS A 1 204 ? 156.779 115.231 148.006 1.00 67.28  1  203 LYS A NZ  1 
ATOM   1586 N  N   . TYR A 1 205 ? 163.383 118.607 150.172 1.00 67.28  0  204 TYR A N   1 
ATOM   1587 C  CA  . TYR A 1 205 ? 164.218 119.416 149.298 1.00 67.28  0  204 TYR A CA  1 
ATOM   1588 C  C   . TYR A 1 205 ? 165.333 120.051 150.116 1.00 67.28  0  204 TYR A C   1 
ATOM   1589 O  O   . TYR A 1 205 ? 165.113 120.485 151.250 1.00 67.28  0  204 TYR A O   1 
ATOM   1590 C  CB  . TYR A 1 205 ? 163.385 120.488 148.591 1.00 67.28  0  204 TYR A CB  1 
ATOM   1591 C  CG  . TYR A 1 205 ? 162.275 119.913 147.740 1.00 67.28  0  204 TYR A CG  1 
ATOM   1592 C  CD1 . TYR A 1 205 ? 162.490 118.789 146.955 1.00 67.28  0  204 TYR A CD1 1 
ATOM   1593 C  CD2 . TYR A 1 205 ? 161.009 120.479 147.739 1.00 67.28  0  204 TYR A CD2 1 
ATOM   1594 C  CE1 . TYR A 1 205 ? 161.479 118.253 146.182 1.00 67.28  0  204 TYR A CE1 1 
ATOM   1595 C  CE2 . TYR A 1 205 ? 159.992 119.949 146.969 1.00 67.28  0  204 TYR A CE2 1 
ATOM   1596 C  CZ  . TYR A 1 205 ? 160.232 118.837 146.193 1.00 67.28  0  204 TYR A CZ  1 
ATOM   1597 O  OH  . TYR A 1 205 ? 159.220 118.308 145.425 1.00 67.28  0  204 TYR A OH  1 
ATOM   1598 N  N   . GLY A 1 206 ? 166.532 120.096 149.532 1.00 67.28  0  205 GLY A N   1 
ATOM   1599 C  CA  . GLY A 1 206 ? 167.703 120.505 150.292 1.00 67.28  0  205 GLY A CA  1 
ATOM   1600 C  C   . GLY A 1 206 ? 167.670 121.957 150.730 1.00 67.28  0  205 GLY A C   1 
ATOM   1601 O  O   . GLY A 1 206 ? 167.999 122.274 151.876 1.00 67.28  0  205 GLY A O   1 
ATOM   1602 N  N   . ASP A 1 207 ? 167.278 122.856 149.832 1.00 67.28  0  206 ASP A N   1 
ATOM   1603 C  CA  . ASP A 1 207 ? 167.349 124.287 150.096 1.00 67.28  0  206 ASP A CA  1 
ATOM   1604 C  C   . ASP A 1 207 ? 166.084 124.848 150.731 1.00 67.28  0  206 ASP A C   1 
ATOM   1605 O  O   . ASP A 1 207 ? 166.010 126.061 150.956 1.00 67.28  0  206 ASP A O   1 
ATOM   1606 C  CB  . ASP A 1 207 ? 167.651 125.047 148.800 1.00 67.28  0  206 ASP A CB  1 
ATOM   1607 C  CG  . ASP A 1 207 ? 169.071 124.828 148.315 1.00 67.28  0  206 ASP A CG  1 
ATOM   1608 O  OD1 . ASP A 1 207 ? 169.961 124.600 149.161 1.00 67.28  0  206 ASP A OD1 1 
ATOM   1609 O  OD2 . ASP A 1 207 ? 169.297 124.886 147.088 1.00 67.28  -1 206 ASP A OD2 1 
ATOM   1610 N  N   . LEU A 1 208 ? 165.095 124.011 151.026 1.00 67.28  0  207 LEU A N   1 
ATOM   1611 C  CA  . LEU A 1 208 ? 163.827 124.456 151.589 1.00 67.28  0  207 LEU A CA  1 
ATOM   1612 C  C   . LEU A 1 208 ? 163.763 124.046 153.054 1.00 67.28  0  207 LEU A C   1 
ATOM   1613 O  O   . LEU A 1 208 ? 163.891 122.860 153.377 1.00 67.28  0  207 LEU A O   1 
ATOM   1614 C  CB  . LEU A 1 208 ? 162.650 123.871 150.806 1.00 67.28  0  207 LEU A CB  1 
ATOM   1615 C  CG  . LEU A 1 208 ? 161.236 124.380 151.101 1.00 67.28  0  207 LEU A CG  1 
ATOM   1616 C  CD1 . LEU A 1 208 ? 160.380 124.259 149.856 1.00 67.28  0  207 LEU A CD1 1 
ATOM   1617 C  CD2 . LEU A 1 208 ? 160.591 123.616 152.248 1.00 67.28  0  207 LEU A CD2 1 
ATOM   1618 N  N   . ASP A 1 209 ? 163.568 125.025 153.934 1.00 67.28  0  208 ASP A N   1 
ATOM   1619 C  CA  . ASP A 1 209 ? 163.371 124.747 155.349 1.00 67.28  0  208 ASP A CA  1 
ATOM   1620 C  C   . ASP A 1 209 ? 161.893 124.501 155.620 1.00 67.28  0  208 ASP A C   1 
ATOM   1621 O  O   . ASP A 1 209 ? 161.031 125.244 155.140 1.00 67.28  0  208 ASP A O   1 
ATOM   1622 C  CB  . ASP A 1 209 ? 163.886 125.903 156.203 1.00 60.46  0  208 ASP A CB  1 
ATOM   1623 C  CG  . ASP A 1 209 ? 164.367 125.450 157.568 1.00 60.46  0  208 ASP A CG  1 
ATOM   1624 O  OD1 . ASP A 1 209 ? 163.517 125.100 158.414 1.00 60.46  0  208 ASP A OD1 1 
ATOM   1625 O  OD2 . ASP A 1 209 ? 165.594 125.441 157.796 1.00 60.46  -1 208 ASP A OD2 1 
ATOM   1626 N  N   . SER A 1 210 ? 161.603 123.449 156.387 1.00 58.09  0  209 SER A N   1 
ATOM   1627 C  CA  . SER A 1 210 ? 160.217 123.070 156.639 1.00 58.09  0  209 SER A CA  1 
ATOM   1628 C  C   . SER A 1 210 ? 159.471 124.149 157.415 1.00 58.09  0  209 SER A C   1 
ATOM   1629 O  O   . SER A 1 210 ? 158.319 124.467 157.098 1.00 58.09  0  209 SER A O   1 
ATOM   1630 C  CB  . SER A 1 210 ? 160.173 121.742 157.393 1.00 58.09  0  209 SER A CB  1 
ATOM   1631 O  OG  . SER A 1 210 ? 158.848 121.252 157.485 1.00 58.09  0  209 SER A OG  1 
ATOM   1632 N  N   . SER A 1 211 ? 160.111 124.724 158.434 1.00 67.28  0  210 SER A N   1 
ATOM   1633 C  CA  . SER A 1 211 ? 159.431 125.652 159.331 1.00 67.28  0  210 SER A CA  1 
ATOM   1634 C  C   . SER A 1 211 ? 159.132 127.002 158.693 1.00 67.28  0  210 SER A C   1 
ATOM   1635 O  O   . SER A 1 211 ? 158.329 127.760 159.247 1.00 67.28  0  210 SER A O   1 
ATOM   1636 C  CB  . SER A 1 211 ? 160.266 125.858 160.596 1.00 67.28  0  210 SER A CB  1 
ATOM   1637 O  OG  . SER A 1 211 ? 160.174 124.735 161.456 1.00 67.28  0  210 SER A OG  1 
ATOM   1638 N  N   . LEU A 1 212 ? 159.747 127.324 157.556 1.00 67.28  0  211 LEU A N   1 
ATOM   1639 C  CA  . LEU A 1 212 ? 159.552 128.631 156.941 1.00 67.28  0  211 LEU A CA  1 
ATOM   1640 C  C   . LEU A 1 212 ? 158.253 128.739 156.154 1.00 67.28  0  211 LEU A C   1 
ATOM   1641 O  O   . LEU A 1 212 ? 157.911 129.840 155.708 1.00 67.28  0  211 LEU A O   1 
ATOM   1642 C  CB  . LEU A 1 212 ? 160.734 128.964 156.029 1.00 67.28  0  211 LEU A CB  1 
ATOM   1643 C  CG  . LEU A 1 212 ? 162.069 129.221 156.728 1.00 67.28  0  211 LEU A CG  1 
ATOM   1644 C  CD1 . LEU A 1 212 ? 163.172 129.463 155.710 1.00 67.28  0  211 LEU A CD1 1 
ATOM   1645 C  CD2 . LEU A 1 212 ? 161.954 130.396 157.687 1.00 67.28  0  211 LEU A CD2 1 
ATOM   1646 N  N   . ILE A 1 213 ? 157.525 127.642 155.972 1.00 67.28  0  212 ILE A N   1 
ATOM   1647 C  CA  . ILE A 1 213 ? 156.265 127.656 155.238 1.00 67.28  0  212 ILE A CA  1 
ATOM   1648 C  C   . ILE A 1 213 ? 155.126 127.874 156.223 1.00 67.28  0  212 ILE A C   1 
ATOM   1649 O  O   . ILE A 1 213 ? 155.000 127.144 157.214 1.00 67.28  0  212 ILE A O   1 
ATOM   1650 C  CB  . ILE A 1 213 ? 156.070 126.350 154.452 1.00 67.28  0  212 ILE A CB  1 
ATOM   1651 C  CG1 . ILE A 1 213 ? 157.153 126.204 153.382 1.00 67.28  0  212 ILE A CG1 1 
ATOM   1652 C  CG2 . ILE A 1 213 ? 154.688 126.308 153.823 1.00 67.28  0  212 ILE A CG2 1 
ATOM   1653 C  CD1 . ILE A 1 213 ? 157.123 124.874 152.666 1.00 67.28  0  212 ILE A CD1 1 
ATOM   1654 N  N   . SER A 1 214 ? 154.295 128.878 155.953 1.00 67.28  0  213 SER A N   1 
ATOM   1655 C  CA  . SER A 1 214 ? 153.169 129.190 156.819 1.00 67.28  0  213 SER A CA  1 
ATOM   1656 C  C   . SER A 1 214 ? 152.033 129.759 155.983 1.00 67.28  0  213 SER A C   1 
ATOM   1657 O  O   . SER A 1 214 ? 152.254 130.320 154.907 1.00 67.28  0  213 SER A O   1 
ATOM   1658 C  CB  . SER A 1 214 ? 153.564 130.180 157.921 1.00 67.28  0  213 SER A CB  1 
ATOM   1659 O  OG  . SER A 1 214 ? 153.900 131.443 157.374 1.00 67.28  0  213 SER A OG  1 
ATOM   1660 N  N   . PHE A 1 215 ? 150.813 129.608 156.492 1.00 67.28  0  214 PHE A N   1 
ATOM   1661 C  CA  . PHE A 1 215 ? 149.619 130.126 155.843 1.00 67.28  0  214 PHE A CA  1 
ATOM   1662 C  C   . PHE A 1 215 ? 148.783 130.890 156.857 1.00 67.28  0  214 PHE A C   1 
ATOM   1663 O  O   . PHE A 1 215 ? 148.764 130.561 158.046 1.00 67.28  0  214 PHE A O   1 
ATOM   1664 C  CB  . PHE A 1 215 ? 148.782 129.001 155.217 1.00 67.28  0  214 PHE A CB  1 
ATOM   1665 C  CG  . PHE A 1 215 ? 147.440 129.451 154.708 1.00 67.28  0  214 PHE A CG  1 
ATOM   1666 C  CD1 . PHE A 1 215 ? 147.331 130.125 153.505 1.00 67.28  0  214 PHE A CD1 1 
ATOM   1667 C  CD2 . PHE A 1 215 ? 146.289 129.202 155.436 1.00 67.28  0  214 PHE A CD2 1 
ATOM   1668 C  CE1 . PHE A 1 215 ? 146.101 130.540 153.036 1.00 67.28  0  214 PHE A CE1 1 
ATOM   1669 C  CE2 . PHE A 1 215 ? 145.055 129.615 154.971 1.00 67.28  0  214 PHE A CE2 1 
ATOM   1670 C  CZ  . PHE A 1 215 ? 144.962 130.286 153.770 1.00 67.28  0  214 PHE A CZ  1 
ATOM   1671 N  N   . GLY A 1 216 ? 148.093 131.920 156.375 1.00 67.28  0  215 GLY A N   1 
ATOM   1672 C  CA  . GLY A 1 216 ? 147.224 132.711 157.210 1.00 67.28  0  215 GLY A CA  1 
ATOM   1673 C  C   . GLY A 1 216 ? 146.092 133.334 156.420 1.00 67.28  0  215 GLY A C   1 
ATOM   1674 O  O   . GLY A 1 216 ? 146.239 133.674 155.242 1.00 67.28  0  215 GLY A O   1 
ATOM   1675 N  N   . PRO A 1 217 ? 144.928 133.487 157.057 1.00 67.28  0  216 PRO A N   1 
ATOM   1676 C  CA  . PRO A 1 217 ? 143.794 134.134 156.376 1.00 67.28  0  216 PRO A CA  1 
ATOM   1677 C  C   . PRO A 1 217 ? 144.050 135.587 156.007 1.00 67.28  0  216 PRO A C   1 
ATOM   1678 O  O   . PRO A 1 217 ? 143.274 136.149 155.225 1.00 67.28  0  216 PRO A O   1 
ATOM   1679 C  CB  . PRO A 1 217 ? 142.651 134.016 157.393 1.00 67.28  0  216 PRO A CB  1 
ATOM   1680 C  CG  . PRO A 1 217 ? 143.048 132.913 158.309 1.00 67.28  0  216 PRO A CG  1 
ATOM   1681 C  CD  . PRO A 1 217 ? 144.545 132.882 158.343 1.00 67.28  0  216 PRO A CD  1 
ATOM   1682 N  N   . CYS A 1 218 ? 145.090 136.212 156.550 1.00 67.28  0  217 CYS A N   1 
ATOM   1683 C  CA  . CYS A 1 218 ? 145.446 137.586 156.216 1.00 67.28  0  217 CYS A CA  1 
ATOM   1684 C  C   . CYS A 1 218 ? 146.845 137.720 155.641 1.00 67.28  0  217 CYS A C   1 
ATOM   1685 O  O   . CYS A 1 218 ? 147.061 138.540 154.742 1.00 67.28  0  217 CYS A O   1 
ATOM   1686 C  CB  . CYS A 1 218 ? 145.320 138.481 157.455 1.00 67.28  0  217 CYS A CB  1 
ATOM   1687 S  SG  . CYS A 1 218 ? 143.635 138.658 158.076 1.00 67.28  0  217 CYS A SG  1 
ATOM   1688 N  N   . GLN A 1 219 ? 147.804 136.932 156.135 1.00 67.28  0  218 GLN A N   1 
ATOM   1689 C  CA  . GLN A 1 219 ? 149.174 137.023 155.639 1.00 67.28  0  218 GLN A CA  1 
ATOM   1690 C  C   . GLN A 1 219 ? 149.251 136.657 154.163 1.00 67.28  0  218 GLN A C   1 
ATOM   1691 O  O   . GLN A 1 219 ? 149.908 137.344 153.373 1.00 67.28  0  218 GLN A O   1 
ATOM   1692 C  CB  . GLN A 1 219 ? 150.088 136.119 156.465 1.00 67.28  0  218 GLN A CB  1 
ATOM   1693 C  CG  . GLN A 1 219 ? 150.217 136.527 157.920 1.00 67.28  0  218 GLN A CG  1 
ATOM   1694 C  CD  . GLN A 1 219 ? 151.046 135.546 158.723 1.00 67.28  0  218 GLN A CD  1 
ATOM   1695 O  OE1 . GLN A 1 219 ? 151.580 134.578 158.180 1.00 67.28  0  218 GLN A OE1 1 
ATOM   1696 N  NE2 . GLN A 1 219 ? 151.158 135.789 160.023 1.00 67.28  0  218 GLN A NE2 1 
ATOM   1697 N  N   . THR A 1 220 ? 148.590 135.569 153.771 1.00 67.28  0  219 THR A N   1 
ATOM   1698 C  CA  . THR A 1 220 ? 148.574 135.194 152.359 1.00 67.28  0  219 THR A CA  1 
ATOM   1699 C  C   . THR A 1 220 ? 147.858 136.222 151.490 1.00 67.28  0  219 THR A C   1 
ATOM   1700 O  O   . THR A 1 220 ? 148.395 136.572 150.424 1.00 67.28  0  219 THR A O   1 
ATOM   1701 C  CB  . THR A 1 220 ? 147.977 133.791 152.202 1.00 67.28  0  219 THR A CB  1 
ATOM   1702 O  OG1 . THR A 1 220 ? 148.783 132.848 152.917 1.00 67.28  0  219 THR A OG1 1 
ATOM   1703 C  CG2 . THR A 1 220 ? 147.928 133.392 150.737 1.00 67.28  0  219 THR A CG2 1 
ATOM   1704 N  N   . PRO A 1 221 ? 146.670 136.731 151.848 1.00 67.28  0  220 PRO A N   1 
ATOM   1705 C  CA  . PRO A 1 221 ? 146.087 137.813 151.034 1.00 67.28  0  220 PRO A CA  1 
ATOM   1706 C  C   . PRO A 1 221 ? 146.954 139.057 150.941 1.00 67.28  0  220 PRO A C   1 
ATOM   1707 O  O   . PRO A 1 221 ? 147.019 139.670 149.868 1.00 67.28  0  220 PRO A O   1 
ATOM   1708 C  CB  . PRO A 1 221 ? 144.759 138.097 151.744 1.00 67.28  0  220 PRO A CB  1 
ATOM   1709 C  CG  . PRO A 1 221 ? 144.397 136.805 152.351 1.00 67.28  0  220 PRO A CG  1 
ATOM   1710 C  CD  . PRO A 1 221 ? 145.695 136.226 152.832 1.00 67.28  0  220 PRO A CD  1 
ATOM   1711 N  N   . THR A 1 222 ? 147.626 139.458 152.025 1.00 67.28  0  221 THR A N   1 
ATOM   1712 C  CA  . THR A 1 222 ? 148.444 140.665 151.956 1.00 67.28  0  221 THR A CA  1 
ATOM   1713 C  C   . THR A 1 222 ? 149.767 140.433 151.237 1.00 67.28  0  221 THR A C   1 
ATOM   1714 O  O   . THR A 1 222 ? 150.370 141.398 150.753 1.00 67.28  0  221 THR A O   1 
ATOM   1715 C  CB  . THR A 1 222 ? 148.697 141.232 153.357 1.00 67.28  0  221 THR A CB  1 
ATOM   1716 O  OG1 . THR A 1 222 ? 149.242 142.552 153.246 1.00 67.28  0  221 THR A OG1 1 
ATOM   1717 C  CG2 . THR A 1 222 ? 149.669 140.368 154.126 1.00 67.28  0  221 THR A CG2 1 
ATOM   1718 N  N   . LEU A 1 223 ? 150.231 139.185 151.156 1.00 67.28  0  222 LEU A N   1 
ATOM   1719 C  CA  . LEU A 1 223 ? 151.360 138.846 150.300 1.00 67.28  0  222 LEU A CA  1 
ATOM   1720 C  C   . LEU A 1 223 ? 150.946 138.699 148.843 1.00 67.28  0  222 LEU A C   1 
ATOM   1721 O  O   . LEU A 1 223 ? 151.794 138.828 147.947 1.00 67.28  0  222 LEU A O   1 
ATOM   1722 C  CB  . LEU A 1 223 ? 152.009 137.552 150.797 1.00 67.28  0  222 LEU A CB  1 
ATOM   1723 C  CG  . LEU A 1 223 ? 153.328 137.096 150.178 1.00 67.28  0  222 LEU A CG  1 
ATOM   1724 C  CD1 . LEU A 1 223 ? 154.330 138.226 150.165 1.00 67.28  0  222 LEU A CD1 1 
ATOM   1725 C  CD2 . LEU A 1 223 ? 153.876 135.903 150.940 1.00 67.28  0  222 LEU A CD2 1 
ATOM   1726 N  N   . GLY A 1 224 ? 149.664 138.426 148.597 1.00 67.28  0  223 GLY A N   1 
ATOM   1727 C  CA  . GLY A 1 224 ? 149.186 138.319 147.230 1.00 67.28  0  223 GLY A CA  1 
ATOM   1728 C  C   . GLY A 1 224 ? 149.356 139.604 146.446 1.00 67.28  0  223 GLY A C   1 
ATOM   1729 O  O   . GLY A 1 224 ? 149.667 139.576 145.256 1.00 67.28  0  223 GLY A O   1 
ATOM   1730 N  N   . PHE A 1 225 ? 149.155 140.750 147.100 1.00 67.28  0  224 PHE A N   1 
ATOM   1731 C  CA  . PHE A 1 225 ? 149.346 142.025 146.414 1.00 67.28  0  224 PHE A CA  1 
ATOM   1732 C  C   . PHE A 1 225 ? 150.800 142.219 146.005 1.00 67.28  0  224 PHE A C   1 
ATOM   1733 O  O   . PHE A 1 225 ? 151.087 142.657 144.883 1.00 67.28  0  224 PHE A O   1 
ATOM   1734 C  CB  . PHE A 1 225 ? 148.882 143.174 147.306 1.00 67.28  0  224 PHE A CB  1 
ATOM   1735 C  CG  . PHE A 1 225 ? 147.460 143.048 147.763 1.00 67.28  0  224 PHE A CG  1 
ATOM   1736 C  CD1 . PHE A 1 225 ? 146.446 142.810 146.854 1.00 67.28  0  224 PHE A CD1 1 
ATOM   1737 C  CD2 . PHE A 1 225 ? 147.138 143.170 149.102 1.00 67.28  0  224 PHE A CD2 1 
ATOM   1738 C  CE1 . PHE A 1 225 ? 145.138 142.694 147.273 1.00 67.28  0  224 PHE A CE1 1 
ATOM   1739 C  CE2 . PHE A 1 225 ? 145.833 143.056 149.526 1.00 67.28  0  224 PHE A CE2 1 
ATOM   1740 C  CZ  . PHE A 1 225 ? 144.832 142.817 148.611 1.00 67.28  0  224 PHE A CZ  1 
ATOM   1741 N  N   . CYS A 1 226 ? 151.734 141.896 146.903 1.00 67.28  0  225 CYS A N   1 
ATOM   1742 C  CA  . CYS A 1 226 ? 153.149 142.033 146.580 1.00 67.28  0  225 CYS A CA  1 
ATOM   1743 C  C   . CYS A 1 226 ? 153.549 141.100 145.445 1.00 67.28  0  225 CYS A C   1 
ATOM   1744 O  O   . CYS A 1 226 ? 154.270 141.505 144.523 1.00 67.28  0  225 CYS A O   1 
ATOM   1745 C  CB  . CYS A 1 226 ? 153.998 141.767 147.822 1.00 67.28  0  225 CYS A CB  1 
ATOM   1746 S  SG  . CYS A 1 226 ? 153.540 142.758 149.262 1.00 67.28  0  225 CYS A SG  1 
ATOM   1747 N  N   . VAL A 1 227 ? 153.082 139.850 145.481 1.00 67.28  0  226 VAL A N   1 
ATOM   1748 C  CA  . VAL A 1 227 ? 153.451 138.929 144.409 1.00 67.28  0  226 VAL A CA  1 
ATOM   1749 C  C   . VAL A 1 227 ? 152.767 139.312 143.101 1.00 67.28  0  226 VAL A C   1 
ATOM   1750 O  O   . VAL A 1 227 ? 153.317 139.076 142.021 1.00 67.28  0  226 VAL A O   1 
ATOM   1751 C  CB  . VAL A 1 227 ? 153.152 137.469 144.796 1.00 67.28  0  226 VAL A CB  1 
ATOM   1752 C  CG1 . VAL A 1 227 ? 153.772 137.136 146.144 1.00 67.28  0  226 VAL A CG1 1 
ATOM   1753 C  CG2 . VAL A 1 227 ? 151.664 137.211 144.797 1.00 67.28  0  226 VAL A CG2 1 
ATOM   1754 N  N   . GLU A 1 228 ? 151.575 139.911 143.160 1.00 67.28  0  227 GLU A N   1 
ATOM   1755 C  CA  . GLU A 1 228 ? 150.920 140.375 141.942 1.00 67.28  0  227 GLU A CA  1 
ATOM   1756 C  C   . GLU A 1 228 ? 151.678 141.544 141.327 1.00 67.28  0  227 GLU A C   1 
ATOM   1757 O  O   . GLU A 1 228 ? 151.834 141.620 140.101 1.00 67.28  0  227 GLU A O   1 
ATOM   1758 C  CB  . GLU A 1 228 ? 149.474 140.764 142.245 1.00 67.28  0  227 GLU A CB  1 
ATOM   1759 C  CG  . GLU A 1 228 ? 148.530 140.635 141.065 1.00 67.28  0  227 GLU A CG  1 
ATOM   1760 C  CD  . GLU A 1 228 ? 147.995 139.225 140.897 1.00 67.28  0  227 GLU A CD  1 
ATOM   1761 O  OE1 . GLU A 1 228 ? 148.278 138.371 141.763 1.00 67.28  0  227 GLU A OE1 1 
ATOM   1762 O  OE2 . GLU A 1 228 ? 147.290 138.971 139.898 1.00 67.28  -1 227 GLU A OE2 1 
ATOM   1763 N  N   . ARG A 1 229 ? 152.162 142.462 142.166 1.00 67.28  0  228 ARG A N   1 
ATOM   1764 C  CA  . ARG A 1 229 ? 153.013 143.536 141.666 1.00 67.28  0  228 ARG A CA  1 
ATOM   1765 C  C   . ARG A 1 229 ? 154.294 142.978 141.061 1.00 67.28  0  228 ARG A C   1 
ATOM   1766 O  O   . ARG A 1 229 ? 154.749 143.446 140.012 1.00 67.28  0  228 ARG A O   1 
ATOM   1767 C  CB  . ARG A 1 229 ? 153.332 144.523 142.788 1.00 67.28  0  228 ARG A CB  1 
ATOM   1768 C  CG  . ARG A 1 229 ? 154.105 145.748 142.330 1.00 67.28  0  228 ARG A CG  1 
ATOM   1769 C  CD  . ARG A 1 229 ? 153.453 146.400 141.123 1.00 67.28  0  228 ARG A CD  1 
ATOM   1770 N  NE  . ARG A 1 229 ? 152.122 146.909 141.427 1.00 67.28  0  228 ARG A NE  1 
ATOM   1771 C  CZ  . ARG A 1 229 ? 151.869 148.148 141.824 1.00 67.28  0  228 ARG A CZ  1 
ATOM   1772 N  NH1 . ARG A 1 229 ? 152.838 149.036 141.978 1.00 67.28  1  228 ARG A NH1 1 
ATOM   1773 N  NH2 . ARG A 1 229 ? 150.613 148.507 142.071 1.00 67.28  0  228 ARG A NH2 1 
ATOM   1774 N  N   . HIS A 1 230 ? 154.884 141.968 141.706 1.00 67.28  0  229 HIS A N   1 
ATOM   1775 C  CA  . HIS A 1 230 ? 156.078 141.333 141.155 1.00 67.28  0  229 HIS A CA  1 
ATOM   1776 C  C   . HIS A 1 230 ? 155.788 140.686 139.805 1.00 67.28  0  229 HIS A C   1 
ATOM   1777 O  O   . HIS A 1 230 ? 156.610 140.758 138.883 1.00 67.28  0  229 HIS A O   1 
ATOM   1778 C  CB  . HIS A 1 230 ? 156.621 140.298 142.139 1.00 67.28  0  229 HIS A CB  1 
ATOM   1779 C  CG  . HIS A 1 230 ? 157.731 139.461 141.585 1.00 67.28  0  229 HIS A CG  1 
ATOM   1780 N  ND1 . HIS A 1 230 ? 159.043 139.882 141.567 1.00 67.28  0  229 HIS A ND1 1 
ATOM   1781 C  CD2 . HIS A 1 230 ? 157.725 138.226 141.031 1.00 67.28  0  229 HIS A CD2 1 
ATOM   1782 C  CE1 . HIS A 1 230 ? 159.797 138.943 141.025 1.00 67.28  0  229 HIS A CE1 1 
ATOM   1783 N  NE2 . HIS A 1 230 ? 159.021 137.928 140.690 1.00 67.28  0  229 HIS A NE2 1 
ATOM   1784 N  N   . ASP A 1 231 ? 154.629 140.038 139.677 1.00 67.28  0  230 ASP A N   1 
ATOM   1785 C  CA  . ASP A 1 231 ? 154.254 139.418 138.411 1.00 67.28  0  230 ASP A CA  1 
ATOM   1786 C  C   . ASP A 1 231 ? 154.068 140.461 137.318 1.00 67.28  0  230 ASP A C   1 
ATOM   1787 O  O   . ASP A 1 231 ? 154.475 140.247 136.171 1.00 67.28  0  230 ASP A O   1 
ATOM   1788 C  CB  . ASP A 1 231 ? 152.980 138.592 138.590 1.00 67.28  0  230 ASP A CB  1 
ATOM   1789 C  CG  . ASP A 1 231 ? 153.221 137.308 139.360 1.00 67.28  0  230 ASP A CG  1 
ATOM   1790 O  OD1 . ASP A 1 231 ? 154.399 136.968 139.599 1.00 67.28  0  230 ASP A OD1 1 
ATOM   1791 O  OD2 . ASP A 1 231 ? 152.232 136.640 139.729 1.00 67.28  -1 230 ASP A OD2 1 
ATOM   1792 N  N   . LYS A 1 232 ? 153.447 141.596 137.650 1.00 67.28  0  231 LYS A N   1 
ATOM   1793 C  CA  . LYS A 1 232 ? 153.325 142.672 136.669 1.00 67.28  0  231 LYS A CA  1 
ATOM   1794 C  C   . LYS A 1 232 ? 154.689 143.227 136.276 1.00 67.28  0  231 LYS A C   1 
ATOM   1795 O  O   . LYS A 1 232 ? 154.912 143.568 135.109 1.00 67.28  0  231 LYS A O   1 
ATOM   1796 C  CB  . LYS A 1 232 ? 152.425 143.788 137.197 1.00 67.28  0  231 LYS A CB  1 
ATOM   1797 C  CG  . LYS A 1 232 ? 150.973 143.388 137.384 1.00 67.28  0  231 LYS A CG  1 
ATOM   1798 C  CD  . LYS A 1 232 ? 150.149 144.559 137.894 1.00 67.28  0  231 LYS A CD  1 
ATOM   1799 C  CE  . LYS A 1 232 ? 148.676 144.203 137.998 1.00 67.28  0  231 LYS A CE  1 
ATOM   1800 N  NZ  . LYS A 1 232 ? 148.417 143.179 139.042 1.00 67.28  1  231 LYS A NZ  1 
ATOM   1801 N  N   . ILE A 1 233 ? 155.609 143.338 137.237 1.00 67.28  0  232 ILE A N   1 
ATOM   1802 C  CA  . ILE A 1 233 ? 156.956 143.816 136.927 1.00 67.28  0  232 ILE A CA  1 
ATOM   1803 C  C   . ILE A 1 233 ? 157.656 142.852 135.976 1.00 67.28  0  232 ILE A C   1 
ATOM   1804 O  O   . ILE A 1 233 ? 158.259 143.263 134.977 1.00 67.28  0  232 ILE A O   1 
ATOM   1805 C  CB  . ILE A 1 233 ? 157.768 144.015 138.219 1.00 67.28  0  232 ILE A CB  1 
ATOM   1806 C  CG1 . ILE A 1 233 ? 157.152 145.115 139.084 1.00 67.28  0  232 ILE A CG1 1 
ATOM   1807 C  CG2 . ILE A 1 233 ? 159.219 144.330 137.893 1.00 67.28  0  232 ILE A CG2 1 
ATOM   1808 C  CD1 . ILE A 1 233 ? 158.070 145.622 140.175 1.00 67.28  0  232 ILE A CD1 1 
ATOM   1809 N  N   . GLN A 1 234 ? 157.578 141.555 136.269 1.00 67.28  0  233 GLN A N   1 
ATOM   1810 C  CA  . GLN A 1 234 ? 158.278 140.551 135.479 1.00 67.28  0  233 GLN A CA  1 
ATOM   1811 C  C   . GLN A 1 234 ? 157.609 140.261 134.143 1.00 67.28  0  233 GLN A C   1 
ATOM   1812 O  O   . GLN A 1 234 ? 158.269 139.730 133.244 1.00 67.28  0  233 GLN A O   1 
ATOM   1813 C  CB  . GLN A 1 234 ? 158.406 139.251 136.275 1.00 67.28  0  233 GLN A CB  1 
ATOM   1814 C  CG  . GLN A 1 234 ? 159.244 139.379 137.534 1.00 67.28  0  233 GLN A CG  1 
ATOM   1815 C  CD  . GLN A 1 234 ? 160.728 139.221 137.267 1.00 67.28  0  233 GLN A CD  1 
ATOM   1816 O  OE1 . GLN A 1 234 ? 161.209 138.118 137.010 1.00 67.28  0  233 GLN A OE1 1 
ATOM   1817 N  NE2 . GLN A 1 234 ? 161.462 140.325 137.330 1.00 67.28  0  233 GLN A NE2 1 
ATOM   1818 N  N   . SER A 1 235 ? 156.328 140.590 133.988 1.00 67.28  0  234 SER A N   1 
ATOM   1819 C  CA  . SER A 1 235 ? 155.601 140.365 132.746 1.00 67.28  0  234 SER A CA  1 
ATOM   1820 C  C   . SER A 1 235 ? 155.243 141.676 132.053 1.00 67.28  0  234 SER A C   1 
ATOM   1821 O  O   . SER A 1 235 ? 154.167 141.800 131.463 1.00 67.28  0  234 SER A O   1 
ATOM   1822 C  CB  . SER A 1 235 ? 154.342 139.539 133.006 1.00 67.28  0  234 SER A CB  1 
ATOM   1823 O  OG  . SER A 1 235 ? 153.372 140.292 133.713 1.00 67.28  0  234 SER A OG  1 
ATOM   1824 N  N   . PHE A 1 236 ? 156.134 142.660 132.118 1.00 67.28  0  235 PHE A N   1 
ATOM   1825 C  CA  . PHE A 1 236 ? 155.929 143.947 131.469 1.00 67.28  0  235 PHE A CA  1 
ATOM   1826 C  C   . PHE A 1 236 ? 156.474 143.898 130.051 1.00 67.28  0  235 PHE A C   1 
ATOM   1827 O  O   . PHE A 1 236 ? 157.511 143.276 129.797 1.00 67.28  0  235 PHE A O   1 
ATOM   1828 C  CB  . PHE A 1 236 ? 156.603 145.080 132.242 1.00 67.28  0  235 PHE A CB  1 
ATOM   1829 C  CG  . PHE A 1 236 ? 156.071 146.440 131.895 1.00 67.28  0  235 PHE A CG  1 
ATOM   1830 C  CD1 . PHE A 1 236 ? 154.710 146.692 131.916 1.00 67.28  0  235 PHE A CD1 1 
ATOM   1831 C  CD2 . PHE A 1 236 ? 156.928 147.456 131.513 1.00 67.28  0  235 PHE A CD2 1 
ATOM   1832 C  CE1 . PHE A 1 236 ? 154.217 147.939 131.586 1.00 67.28  0  235 PHE A CE1 1 
ATOM   1833 C  CE2 . PHE A 1 236 ? 156.441 148.705 131.181 1.00 67.28  0  235 PHE A CE2 1 
ATOM   1834 C  CZ  . PHE A 1 236 ? 155.084 148.947 131.218 1.00 67.28  0  235 PHE A CZ  1 
ATOM   1835 N  N   . LYS A 1 237 ? 155.773 144.558 129.133 1.00 68.63  0  236 LYS A N   1 
ATOM   1836 C  CA  . LYS A 1 237 ? 156.145 144.577 127.724 1.00 68.63  0  236 LYS A CA  1 
ATOM   1837 C  C   . LYS A 1 237 ? 156.417 146.017 127.314 1.00 68.63  0  236 LYS A C   1 
ATOM   1838 O  O   . LYS A 1 237 ? 155.476 146.752 126.977 1.00 68.63  0  236 LYS A O   1 
ATOM   1839 C  CB  . LYS A 1 237 ? 155.022 143.975 126.875 1.00 68.63  0  236 LYS A CB  1 
ATOM   1840 C  CG  . LYS A 1 237 ? 154.718 142.525 127.221 1.00 68.63  0  236 LYS A CG  1 
ATOM   1841 C  CD  . LYS A 1 237 ? 153.621 141.951 126.344 1.00 68.63  0  236 LYS A CD  1 
ATOM   1842 C  CE  . LYS A 1 237 ? 153.245 140.548 126.794 1.00 68.63  0  236 LYS A CE  1 
ATOM   1843 N  NZ  . LYS A 1 237 ? 153.810 139.498 125.911 1.00 68.63  1  236 LYS A NZ  1 
ATOM   1844 N  N   . PRO A 1 238 ? 157.669 146.474 127.345 1.00 67.28  0  237 PRO A N   1 
ATOM   1845 C  CA  . PRO A 1 238 ? 157.950 147.878 127.020 1.00 67.28  0  237 PRO A CA  1 
ATOM   1846 C  C   . PRO A 1 238 ? 157.501 148.232 125.610 1.00 67.28  0  237 PRO A C   1 
ATOM   1847 O  O   . PRO A 1 238 ? 157.655 147.448 124.671 1.00 67.28  0  237 PRO A O   1 
ATOM   1848 C  CB  . PRO A 1 238 ? 159.472 147.981 127.168 1.00 67.28  0  237 PRO A CB  1 
ATOM   1849 C  CG  . PRO A 1 238 ? 159.851 146.845 128.058 1.00 67.28  0  237 PRO A CG  1 
ATOM   1850 C  CD  . PRO A 1 238 ? 158.881 145.744 127.752 1.00 67.28  0  237 PRO A CD  1 
ATOM   1851 N  N   . GLU A 1 239 ? 156.941 149.431 125.472 1.00 67.28  0  238 GLU A N   1 
ATOM   1852 C  CA  . GLU A 1 239 ? 156.429 149.927 124.205 1.00 67.28  0  238 GLU A CA  1 
ATOM   1853 C  C   . GLU A 1 239 ? 156.931 151.345 123.982 1.00 67.28  0  238 GLU A C   1 
ATOM   1854 O  O   . GLU A 1 239 ? 156.978 152.150 124.917 1.00 67.28  0  238 GLU A O   1 
ATOM   1855 C  CB  . GLU A 1 239 ? 154.897 149.897 124.176 1.00 67.28  0  238 GLU A CB  1 
ATOM   1856 C  CG  . GLU A 1 239 ? 154.311 149.493 122.834 1.00 67.28  0  238 GLU A CG  1 
ATOM   1857 C  CD  . GLU A 1 239 ? 152.798 149.557 122.818 1.00 67.28  0  238 GLU A CD  1 
ATOM   1858 O  OE1 . GLU A 1 239 ? 152.191 149.572 123.909 1.00 67.28  0  238 GLU A OE1 1 
ATOM   1859 O  OE2 . GLU A 1 239 ? 152.215 149.591 121.713 1.00 67.28  -1 238 GLU A OE2 1 
ATOM   1860 N  N   . THR A 1 240 ? 157.306 151.644 122.743 1.00 67.28  0  239 THR A N   1 
ATOM   1861 C  CA  . THR A 1 240 ? 157.887 152.934 122.397 1.00 67.28  0  239 THR A CA  1 
ATOM   1862 C  C   . THR A 1 240 ? 156.792 153.916 122.001 1.00 67.28  0  239 THR A C   1 
ATOM   1863 O  O   . THR A 1 240 ? 155.917 153.588 121.193 1.00 67.28  0  239 THR A O   1 
ATOM   1864 C  CB  . THR A 1 240 ? 158.895 152.781 121.258 1.00 67.28  0  239 THR A CB  1 
ATOM   1865 O  OG1 . THR A 1 240 ? 159.937 151.882 121.655 1.00 67.28  0  239 THR A OG1 1 
ATOM   1866 C  CG2 . THR A 1 240 ? 159.508 154.126 120.903 1.00 67.28  0  239 THR A CG2 1 
ATOM   1867 N  N   . TYR A 1 241 ? 156.845 155.117 122.573 1.00 67.28  0  240 TYR A N   1 
ATOM   1868 C  CA  . TYR A 1 241 ? 155.918 156.188 122.244 1.00 67.28  0  240 TYR A CA  1 
ATOM   1869 C  C   . TYR A 1 241 ? 156.691 157.481 122.031 1.00 67.28  0  240 TYR A C   1 
ATOM   1870 O  O   . TYR A 1 241 ? 157.766 157.682 122.603 1.00 67.28  0  240 TYR A O   1 
ATOM   1871 C  CB  . TYR A 1 241 ? 154.855 156.375 123.337 1.00 67.28  0  240 TYR A CB  1 
ATOM   1872 C  CG  . TYR A 1 241 ? 155.392 156.844 124.670 1.00 67.28  0  240 TYR A CG  1 
ATOM   1873 C  CD1 . TYR A 1 241 ? 155.998 155.957 125.549 1.00 67.28  0  240 TYR A CD1 1 
ATOM   1874 C  CD2 . TYR A 1 241 ? 155.286 158.172 125.053 1.00 67.28  0  240 TYR A CD2 1 
ATOM   1875 C  CE1 . TYR A 1 241 ? 156.485 156.383 126.770 1.00 67.28  0  240 TYR A CE1 1 
ATOM   1876 C  CE2 . TYR A 1 241 ? 155.769 158.606 126.269 1.00 67.28  0  240 TYR A CE2 1 
ATOM   1877 C  CZ  . TYR A 1 241 ? 156.367 157.709 127.124 1.00 67.28  0  240 TYR A CZ  1 
ATOM   1878 O  OH  . TYR A 1 241 ? 156.852 158.138 128.337 1.00 67.28  0  240 TYR A OH  1 
ATOM   1879 N  N   . TRP A 1 242 ? 156.132 158.358 121.202 1.00 67.28  0  241 TRP A N   1 
ATOM   1880 C  CA  . TRP A 1 242 ? 156.798 159.583 120.787 1.00 67.28  0  241 TRP A CA  1 
ATOM   1881 C  C   . TRP A 1 242 ? 156.036 160.797 121.297 1.00 67.28  0  241 TRP A C   1 
ATOM   1882 O  O   . TRP A 1 242 ? 154.802 160.831 121.256 1.00 67.28  0  241 TRP A O   1 
ATOM   1883 C  CB  . TRP A 1 242 ? 156.925 159.651 119.264 1.00 67.28  0  241 TRP A CB  1 
ATOM   1884 C  CG  . TRP A 1 242 ? 157.801 158.585 118.679 1.00 67.28  0  241 TRP A CG  1 
ATOM   1885 C  CD1 . TRP A 1 242 ? 159.088 158.727 118.256 1.00 67.28  0  241 TRP A CD1 1 
ATOM   1886 C  CD2 . TRP A 1 242 ? 157.450 157.216 118.443 1.00 67.28  0  241 TRP A CD2 1 
ATOM   1887 N  NE1 . TRP A 1 242 ? 159.564 157.533 117.776 1.00 67.28  0  241 TRP A NE1 1 
ATOM   1888 C  CE2 . TRP A 1 242 ? 158.578 156.589 117.879 1.00 67.28  0  241 TRP A CE2 1 
ATOM   1889 C  CE3 . TRP A 1 242 ? 156.294 156.460 118.654 1.00 67.28  0  241 TRP A CE3 1 
ATOM   1890 C  CZ2 . TRP A 1 242 ? 158.584 155.243 117.526 1.00 67.28  0  241 TRP A CZ2 1 
ATOM   1891 C  CZ3 . TRP A 1 242 ? 156.302 155.123 118.302 1.00 67.28  0  241 TRP A CZ3 1 
ATOM   1892 C  CH2 . TRP A 1 242 ? 157.439 154.529 117.744 1.00 67.28  0  241 TRP A CH2 1 
ATOM   1893 N  N   . VAL A 1 243 ? 156.780 161.791 121.775 1.00 67.28  0  242 VAL A N   1 
ATOM   1894 C  CA  . VAL A 1 243 ? 156.218 163.026 122.305 1.00 67.28  0  242 VAL A CA  1 
ATOM   1895 C  C   . VAL A 1 243 ? 156.866 164.196 121.579 1.00 67.28  0  242 VAL A C   1 
ATOM   1896 O  O   . VAL A 1 243 ? 158.097 164.288 121.520 1.00 67.28  0  242 VAL A O   1 
ATOM   1897 C  CB  . VAL A 1 243 ? 156.439 163.149 123.824 1.00 67.28  0  242 VAL A CB  1 
ATOM   1898 C  CG1 . VAL A 1 243 ? 155.866 164.458 124.342 1.00 67.28  0  242 VAL A CG1 1 
ATOM   1899 C  CG2 . VAL A 1 243 ? 155.831 161.959 124.552 1.00 67.28  0  242 VAL A CG2 1 
ATOM   1900 N  N   . LEU A 1 244 ? 156.043 165.083 121.027 1.00 67.28  0  243 LEU A N   1 
ATOM   1901 C  CA  . LEU A 1 244 ? 156.552 166.290 120.394 1.00 67.28  0  243 LEU A CA  1 
ATOM   1902 C  C   . LEU A 1 244 ? 156.767 167.381 121.434 1.00 67.28  0  243 LEU A C   1 
ATOM   1903 O  O   . LEU A 1 244 ? 155.929 167.596 122.313 1.00 67.28  0  243 LEU A O   1 
ATOM   1904 C  CB  . LEU A 1 244 ? 155.590 166.780 119.312 1.00 67.28  0  243 LEU A CB  1 
ATOM   1905 C  CG  . LEU A 1 244 ? 155.951 166.420 117.871 1.00 67.28  0  243 LEU A CG  1 
ATOM   1906 C  CD1 . LEU A 1 244 ? 155.776 164.930 117.627 1.00 67.28  0  243 LEU A CD1 1 
ATOM   1907 C  CD2 . LEU A 1 244 ? 155.119 167.232 116.890 1.00 67.28  0  243 LEU A CD2 1 
ATOM   1908 N  N   . GLN A 1 245 ? 157.900 168.071 121.328 1.00 67.28  0  244 GLN A N   1 
ATOM   1909 C  CA  . GLN A 1 245 ? 158.263 169.133 122.256 1.00 67.28  0  244 GLN A CA  1 
ATOM   1910 C  C   . GLN A 1 245 ? 158.529 170.407 121.472 1.00 67.28  0  244 GLN A C   1 
ATOM   1911 O  O   . GLN A 1 245 ? 159.252 170.383 120.471 1.00 67.28  0  244 GLN A O   1 
ATOM   1912 C  CB  . GLN A 1 245 ? 159.494 168.751 123.083 1.00 67.28  0  244 GLN A CB  1 
ATOM   1913 C  CG  . GLN A 1 245 ? 159.169 168.054 124.392 1.00 67.28  0  244 GLN A CG  1 
ATOM   1914 C  CD  . GLN A 1 245 ? 160.334 168.060 125.359 1.00 67.28  0  244 GLN A CD  1 
ATOM   1915 O  OE1 . GLN A 1 245 ? 161.445 168.457 125.007 1.00 67.28  0  244 GLN A OE1 1 
ATOM   1916 N  NE2 . GLN A 1 245 ? 160.088 167.616 126.586 1.00 67.28  0  244 GLN A NE2 1 
ATOM   1917 N  N   . ALA A 1 246 ? 157.950 171.514 121.928 1.00 67.28  0  245 ALA A N   1 
ATOM   1918 C  CA  . ALA A 1 246 ? 158.091 172.806 121.273 1.00 67.28  0  245 ALA A CA  1 
ATOM   1919 C  C   . ALA A 1 246 ? 158.703 173.804 122.243 1.00 67.28  0  245 ALA A C   1 
ATOM   1920 O  O   . ALA A 1 246 ? 158.220 173.959 123.370 1.00 67.28  0  245 ALA A O   1 
ATOM   1921 C  CB  . ALA A 1 246 ? 156.740 173.317 120.768 1.00 67.28  0  245 ALA A CB  1 
ATOM   1922 N  N   . LYS A 1 247 ? 159.763 174.476 121.805 1.00 68.25  0  246 LYS A N   1 
ATOM   1923 C  CA  . LYS A 1 247 ? 160.406 175.535 122.569 1.00 68.25  0  246 LYS A CA  1 
ATOM   1924 C  C   . LYS A 1 247 ? 160.191 176.861 121.854 1.00 68.25  0  246 LYS A C   1 
ATOM   1925 O  O   . LYS A 1 247 ? 160.482 176.978 120.660 1.00 68.25  0  246 LYS A O   1 
ATOM   1926 C  CB  . LYS A 1 247 ? 161.902 175.262 122.737 1.00 68.25  0  246 LYS A CB  1 
ATOM   1927 C  CG  . LYS A 1 247 ? 162.242 174.265 123.830 1.00 68.25  0  246 LYS A CG  1 
ATOM   1928 C  CD  . LYS A 1 247 ? 163.702 174.383 124.240 1.00 68.25  0  246 LYS A CD  1 
ATOM   1929 C  CE  . LYS A 1 247 ? 164.269 173.042 124.675 1.00 68.25  0  246 LYS A CE  1 
ATOM   1930 N  NZ  . LYS A 1 247 ? 163.887 172.705 126.074 1.00 68.25  1  246 LYS A NZ  1 
ATOM   1931 N  N   . VAL A 1 248 ? 159.691 177.856 122.580 1.00 70.82  0  247 VAL A N   1 
ATOM   1932 C  CA  . VAL A 1 248 ? 159.440 179.170 122.001 1.00 70.82  0  247 VAL A CA  1 
ATOM   1933 C  C   . VAL A 1 248 ? 160.189 180.222 122.805 1.00 70.82  0  247 VAL A C   1 
ATOM   1934 O  O   . VAL A 1 248 ? 160.466 180.042 123.994 1.00 70.82  0  247 VAL A O   1 
ATOM   1935 C  CB  . VAL A 1 248 ? 157.932 179.500 121.935 1.00 70.82  0  247 VAL A CB  1 
ATOM   1936 C  CG1 . VAL A 1 248 ? 157.210 178.502 121.044 1.00 70.82  0  247 VAL A CG1 1 
ATOM   1937 C  CG2 . VAL A 1 248 ? 157.327 179.512 123.326 1.00 70.82  0  247 VAL A CG2 1 
ATOM   1938 N  N   . ASN A 1 249 ? 160.526 181.326 122.143 1.00 75.09  0  248 ASN A N   1 
ATOM   1939 C  CA  . ASN A 1 249 ? 161.258 182.424 122.762 1.00 75.09  0  248 ASN A CA  1 
ATOM   1940 C  C   . ASN A 1 249 ? 160.286 183.562 123.042 1.00 75.09  0  248 ASN A C   1 
ATOM   1941 O  O   . ASN A 1 249 ? 159.564 183.999 122.139 1.00 75.09  0  248 ASN A O   1 
ATOM   1942 C  CB  . ASN A 1 249 ? 162.401 182.895 121.863 1.00 75.09  0  248 ASN A CB  1 
ATOM   1943 C  CG  . ASN A 1 249 ? 163.511 181.871 121.748 1.00 75.09  0  248 ASN A CG  1 
ATOM   1944 O  OD1 . ASN A 1 249 ? 163.613 180.955 122.563 1.00 75.09  0  248 ASN A OD1 1 
ATOM   1945 N  ND2 . ASN A 1 249 ? 164.351 182.019 120.730 1.00 75.09  0  248 ASN A ND2 1 
ATOM   1946 N  N   . THR A 1 250 ? 160.266 184.039 124.288 1.00 79.37  0  249 THR A N   1 
ATOM   1947 C  CA  . THR A 1 250 ? 159.259 185.027 124.676 1.00 79.37  0  249 THR A CA  1 
ATOM   1948 C  C   . THR A 1 250 ? 159.663 186.440 124.262 1.00 79.37  0  249 THR A C   1 
ATOM   1949 O  O   . THR A 1 250 ? 159.024 187.049 123.398 1.00 79.37  0  249 THR A O   1 
ATOM   1950 C  CB  . THR A 1 250 ? 159.011 184.957 126.186 1.00 79.37  0  249 THR A CB  1 
ATOM   1951 O  OG1 . THR A 1 250 ? 160.176 185.412 126.883 1.00 79.37  0  249 THR A OG1 1 
ATOM   1952 C  CG2 . THR A 1 250 ? 158.701 183.529 126.605 1.00 79.37  0  249 THR A CG2 1 
ATOM   1953 N  N   . ASP A 1 251 ? 160.722 186.983 124.865 1.00 82.95  0  250 ASP A N   1 
ATOM   1954 C  CA  . ASP A 1 251 ? 161.205 188.311 124.501 1.00 82.95  0  250 ASP A CA  1 
ATOM   1955 C  C   . ASP A 1 251 ? 162.633 188.273 123.966 1.00 82.95  0  250 ASP A C   1 
ATOM   1956 O  O   . ASP A 1 251 ? 162.858 188.599 122.798 1.00 82.95  0  250 ASP A O   1 
ATOM   1957 C  CB  . ASP A 1 251 ? 161.098 189.249 125.706 1.00 82.95  0  250 ASP A CB  1 
ATOM   1958 C  CG  . ASP A 1 251 ? 161.363 190.697 125.344 1.00 82.95  0  250 ASP A CG  1 
ATOM   1959 O  OD1 . ASP A 1 251 ? 160.400 191.407 124.986 1.00 82.95  0  250 ASP A OD1 1 
ATOM   1960 O  OD2 . ASP A 1 251 ? 162.533 191.125 125.421 1.00 82.95  -1 250 ASP A OD2 1 
ATOM   1961 N  N   . LYS A 1 252 ? 163.613 187.885 124.786 1.00 83.77  0  251 LYS A N   1 
ATOM   1962 C  CA  . LYS A 1 252 ? 164.983 187.758 124.298 1.00 83.77  0  251 LYS A CA  1 
ATOM   1963 C  C   . LYS A 1 252 ? 165.733 186.533 124.807 1.00 83.77  0  251 LYS A C   1 
ATOM   1964 O  O   . LYS A 1 252 ? 166.591 186.022 124.081 1.00 83.77  0  251 LYS A O   1 
ATOM   1965 C  CB  . LYS A 1 252 ? 165.792 189.014 124.653 1.00 83.77  0  251 LYS A CB  1 
ATOM   1966 C  CG  . LYS A 1 252 ? 167.014 189.236 123.777 1.00 83.77  0  251 LYS A CG  1 
ATOM   1967 C  CD  . LYS A 1 252 ? 167.963 190.248 124.397 1.00 83.77  0  251 LYS A CD  1 
ATOM   1968 C  CE  . LYS A 1 252 ? 167.673 191.654 123.898 1.00 83.77  0  251 LYS A CE  1 
ATOM   1969 N  NZ  . LYS A 1 252 ? 168.915 192.462 123.755 1.00 83.77  1  251 LYS A NZ  1 
ATOM   1970 N  N   . ASP A 1 253 ? 165.449 186.036 126.011 1.00 84.65  0  252 ASP A N   1 
ATOM   1971 C  CA  . ASP A 1 253 ? 166.246 184.959 126.586 1.00 84.65  0  252 ASP A CA  1 
ATOM   1972 C  C   . ASP A 1 253 ? 165.373 183.842 127.140 1.00 84.65  0  252 ASP A C   1 
ATOM   1973 O  O   . ASP A 1 253 ? 165.772 182.673 127.131 1.00 84.65  0  252 ASP A O   1 
ATOM   1974 C  CB  . ASP A 1 253 ? 167.158 185.504 127.689 1.00 84.65  0  252 ASP A CB  1 
ATOM   1975 C  CG  . ASP A 1 253 ? 168.191 186.482 127.164 1.00 84.65  0  252 ASP A CG  1 
ATOM   1976 O  OD1 . ASP A 1 253 ? 168.647 186.310 126.014 1.00 84.65  0  252 ASP A OD1 1 
ATOM   1977 O  OD2 . ASP A 1 253 ? 168.549 187.424 127.902 1.00 84.65  -1 252 ASP A OD2 1 
ATOM   1978 N  N   . ARG A 1 254 ? 164.187 184.191 127.629 1.00 78.26  0  253 ARG A N   1 
ATOM   1979 C  CA  . ARG A 1 254 ? 163.305 183.195 128.219 1.00 78.26  0  253 ARG A CA  1 
ATOM   1980 C  C   . ARG A 1 254 ? 162.811 182.226 127.153 1.00 78.26  0  253 ARG A C   1 
ATOM   1981 O  O   . ARG A 1 254 ? 162.397 182.632 126.064 1.00 78.26  0  253 ARG A O   1 
ATOM   1982 C  CB  . ARG A 1 254 ? 162.122 183.873 128.909 1.00 78.26  0  253 ARG A CB  1 
ATOM   1983 C  CG  . ARG A 1 254 ? 161.039 182.914 129.373 1.00 78.26  0  253 ARG A CG  1 
ATOM   1984 C  CD  . ARG A 1 254 ? 160.288 183.459 130.578 1.00 78.26  0  253 ARG A CD  1 
ATOM   1985 N  NE  . ARG A 1 254 ? 159.564 182.415 131.295 1.00 78.26  0  253 ARG A NE  1 
ATOM   1986 C  CZ  . ARG A 1 254 ? 160.133 181.480 132.043 1.00 78.26  0  253 ARG A CZ  1 
ATOM   1987 N  NH1 . ARG A 1 254 ? 161.444 181.432 132.214 1.00 78.26  1  253 ARG A NH1 1 
ATOM   1988 N  NH2 . ARG A 1 254 ? 159.366 180.571 132.639 1.00 78.26  0  253 ARG A NH2 1 
ATOM   1989 N  N   . SER A 1 255 ? 162.859 180.936 127.474 1.00 74.53  0  254 SER A N   1 
ATOM   1990 C  CA  . SER A 1 255 ? 162.449 179.878 126.557 1.00 74.53  0  254 SER A CA  1 
ATOM   1991 C  C   . SER A 1 255 ? 161.344 179.067 127.218 1.00 74.53  0  254 SER A C   1 
ATOM   1992 O  O   . SER A 1 255 ? 161.601 178.306 128.157 1.00 74.53  0  254 SER A O   1 
ATOM   1993 C  CB  . SER A 1 255 ? 163.634 178.989 126.181 1.00 74.53  0  254 SER A CB  1 
ATOM   1994 O  OG  . SER A 1 255 ? 163.893 178.031 127.192 1.00 74.53  0  254 SER A OG  1 
ATOM   1995 N  N   . LEU A 1 256 ? 160.119 179.233 126.730 1.00 70.41  0  255 LEU A N   1 
ATOM   1996 C  CA  . LEU A 1 256 ? 159.002 178.426 127.197 1.00 70.41  0  255 LEU A CA  1 
ATOM   1997 C  C   . LEU A 1 256 ? 159.056 177.051 126.549 1.00 70.41  0  255 LEU A C   1 
ATOM   1998 O  O   . LEU A 1 256 ? 159.196 176.935 125.326 1.00 70.41  0  255 LEU A O   1 
ATOM   1999 C  CB  . LEU A 1 256 ? 157.672 179.104 126.874 1.00 70.41  0  255 LEU A CB  1 
ATOM   2000 C  CG  . LEU A 1 256 ? 157.111 180.102 127.885 1.00 70.41  0  255 LEU A CG  1 
ATOM   2001 C  CD1 . LEU A 1 256 ? 156.089 181.000 127.212 1.00 70.41  0  255 LEU A CD1 1 
ATOM   2002 C  CD2 . LEU A 1 256 ? 156.495 179.378 129.069 1.00 70.41  0  255 LEU A CD2 1 
ATOM   2003 N  N   . LEU A 1 257 ? 158.942 176.011 127.371 1.00 67.28  0  256 LEU A N   1 
ATOM   2004 C  CA  . LEU A 1 257 ? 158.919 174.627 126.905 1.00 67.28  0  256 LEU A CA  1 
ATOM   2005 C  C   . LEU A 1 257 ? 157.462 174.177 126.889 1.00 67.28  0  256 LEU A C   1 
ATOM   2006 O  O   . LEU A 1 257 ? 156.896 173.819 127.925 1.00 67.28  0  256 LEU A O   1 
ATOM   2007 C  CB  . LEU A 1 257 ? 159.785 173.742 127.797 1.00 67.28  0  256 LEU A CB  1 
ATOM   2008 C  CG  . LEU A 1 257 ? 159.564 172.227 127.765 1.00 67.28  0  256 LEU A CG  1 
ATOM   2009 C  CD1 . LEU A 1 257 ? 160.189 171.618 126.523 1.00 67.28  0  256 LEU A CD1 1 
ATOM   2010 C  CD2 . LEU A 1 257 ? 160.118 171.576 129.020 1.00 67.28  0  256 LEU A CD2 1 
ATOM   2011 N  N   . LEU A 1 258 ? 156.848 174.223 125.710 1.00 67.28  0  257 LEU A N   1 
ATOM   2012 C  CA  . LEU A 1 258 ? 155.453 173.845 125.561 1.00 67.28  0  257 LEU A CA  1 
ATOM   2013 C  C   . LEU A 1 258 ? 155.317 172.328 125.519 1.00 67.28  0  257 LEU A C   1 
ATOM   2014 O  O   . LEU A 1 258 ? 156.226 171.616 125.086 1.00 67.28  0  257 LEU A O   1 
ATOM   2015 C  CB  . LEU A 1 258 ? 154.868 174.453 124.286 1.00 67.28  0  257 LEU A CB  1 
ATOM   2016 C  CG  . LEU A 1 258 ? 155.180 175.925 124.011 1.00 67.28  0  257 LEU A CG  1 
ATOM   2017 C  CD1 . LEU A 1 258 ? 154.642 176.344 122.655 1.00 67.28  0  257 LEU A CD1 1 
ATOM   2018 C  CD2 . LEU A 1 258 ? 154.609 176.805 125.099 1.00 67.28  0  257 LEU A CD2 1 
ATOM   2019 N  N   . ASP A 1 259 ? 154.172 171.833 125.983 1.00 67.28  0  258 ASP A N   1 
ATOM   2020 C  CA  . ASP A 1 259 ? 153.880 170.409 125.929 1.00 67.28  0  258 ASP A CA  1 
ATOM   2021 C  C   . ASP A 1 259 ? 152.642 170.157 125.078 1.00 67.28  0  258 ASP A C   1 
ATOM   2022 O  O   . ASP A 1 259 ? 151.733 170.991 124.997 1.00 67.28  0  258 ASP A O   1 
ATOM   2023 C  CB  . ASP A 1 259 ? 153.701 169.797 127.331 1.00 67.28  0  258 ASP A CB  1 
ATOM   2024 C  CG  . ASP A 1 259 ? 152.738 170.577 128.199 1.00 67.28  0  258 ASP A CG  1 
ATOM   2025 O  OD1 . ASP A 1 259 ? 152.260 171.638 127.763 1.00 67.28  0  258 ASP A OD1 1 
ATOM   2026 O  OD2 . ASP A 1 259 ? 152.440 170.110 129.318 1.00 67.28  -1 258 ASP A OD2 1 
ATOM   2027 N  N   . TRP A 1 260 ? 152.632 168.997 124.432 1.00 67.28  0  259 TRP A N   1 
ATOM   2028 C  CA  . TRP A 1 260 ? 151.623 168.661 123.438 1.00 67.28  0  259 TRP A CA  1 
ATOM   2029 C  C   . TRP A 1 260 ? 150.303 168.280 124.094 1.00 67.28  0  259 TRP A C   1 
ATOM   2030 O  O   . TRP A 1 260 ? 150.279 167.676 125.169 1.00 67.28  0  259 TRP A O   1 
ATOM   2031 C  CB  . TRP A 1 260 ? 152.137 167.512 122.574 1.00 67.28  0  259 TRP A CB  1 
ATOM   2032 C  CG  . TRP A 1 260 ? 151.556 167.404 121.210 1.00 67.28  0  259 TRP A CG  1 
ATOM   2033 C  CD1 . TRP A 1 260 ? 150.872 168.359 120.517 1.00 67.28  0  259 TRP A CD1 1 
ATOM   2034 C  CD2 . TRP A 1 260 ? 151.643 166.267 120.351 1.00 67.28  0  259 TRP A CD2 1 
ATOM   2035 N  NE1 . TRP A 1 260 ? 150.512 167.875 119.281 1.00 67.28  0  259 TRP A NE1 1 
ATOM   2036 C  CE2 . TRP A 1 260 ? 150.977 166.591 119.156 1.00 67.28  0  259 TRP A CE2 1 
ATOM   2037 C  CE3 . TRP A 1 260 ? 152.215 164.998 120.482 1.00 67.28  0  259 TRP A CE3 1 
ATOM   2038 C  CZ2 . TRP A 1 260 ? 150.868 165.693 118.098 1.00 67.28  0  259 TRP A CZ2 1 
ATOM   2039 C  CZ3 . TRP A 1 260 ? 152.106 164.110 119.433 1.00 67.28  0  259 TRP A CZ3 1 
ATOM   2040 C  CH2 . TRP A 1 260 ? 151.439 164.460 118.258 1.00 67.28  0  259 TRP A CH2 1 
ATOM   2041 N  N   . ASP A 1 261 ? 149.197 168.638 123.437 1.00 67.28  0  260 ASP A N   1 
ATOM   2042 C  CA  . ASP A 1 261 ? 147.890 168.215 123.928 1.00 67.28  0  260 ASP A CA  1 
ATOM   2043 C  C   . ASP A 1 261 ? 147.716 166.709 123.799 1.00 67.28  0  260 ASP A C   1 
ATOM   2044 O  O   . ASP A 1 261 ? 147.202 166.056 124.713 1.00 67.28  0  260 ASP A O   1 
ATOM   2045 C  CB  . ASP A 1 261 ? 146.778 168.937 123.173 1.00 67.28  0  260 ASP A CB  1 
ATOM   2046 C  CG  . ASP A 1 261 ? 146.721 170.416 123.490 1.00 67.28  0  260 ASP A CG  1 
ATOM   2047 O  OD1 . ASP A 1 261 ? 147.103 170.805 124.613 1.00 67.28  0  260 ASP A OD1 1 
ATOM   2048 O  OD2 . ASP A 1 261 ? 146.282 171.185 122.615 1.00 67.28  -1 260 ASP A OD2 1 
ATOM   2049 N  N   . ARG A 1 262 ? 148.153 166.137 122.677 1.00 67.28  0  261 ARG A N   1 
ATOM   2050 C  CA  . ARG A 1 262 ? 147.997 164.705 122.462 1.00 67.28  0  261 ARG A CA  1 
ATOM   2051 C  C   . ARG A 1 262 ? 148.938 163.881 123.327 1.00 67.28  0  261 ARG A C   1 
ATOM   2052 O  O   . ARG A 1 262 ? 148.843 162.648 123.313 1.00 67.28  0  261 ARG A O   1 
ATOM   2053 C  CB  . ARG A 1 262 ? 148.205 164.377 120.983 1.00 67.28  0  261 ARG A CB  1 
ATOM   2054 C  CG  . ARG A 1 262 ? 147.219 165.084 120.067 1.00 67.28  0  261 ARG A CG  1 
ATOM   2055 C  CD  . ARG A 1 262 ? 147.201 164.479 118.678 1.00 67.28  0  261 ARG A CD  1 
ATOM   2056 N  NE  . ARG A 1 262 ? 147.158 165.510 117.648 1.00 67.28  0  261 ARG A NE  1 
ATOM   2057 C  CZ  . ARG A 1 262 ? 146.043 165.992 117.116 1.00 67.28  0  261 ARG A CZ  1 
ATOM   2058 N  NH1 . ARG A 1 262 ? 144.854 165.551 117.490 1.00 67.28  1  261 ARG A NH1 1 
ATOM   2059 N  NH2 . ARG A 1 262 ? 146.124 166.934 116.181 1.00 67.28  0  261 ARG A NH2 1 
ATOM   2060 N  N   . VAL A 1 263 ? 149.848 164.532 124.054 1.00 67.28  0  262 VAL A N   1 
ATOM   2061 C  CA  . VAL A 1 263 ? 150.717 163.895 125.039 1.00 67.28  0  262 VAL A CA  1 
ATOM   2062 C  C   . VAL A 1 263 ? 151.669 162.927 124.353 1.00 67.28  0  262 VAL A C   1 
ATOM   2063 O  O   . VAL A 1 263 ? 152.877 163.179 124.279 1.00 67.28  0  262 VAL A O   1 
ATOM   2064 C  CB  . VAL A 1 263 ? 149.902 163.184 126.134 1.00 67.28  0  262 VAL A CB  1 
ATOM   2065 C  CG1 . VAL A 1 263 ? 150.824 162.442 127.085 1.00 67.28  0  262 VAL A CG1 1 
ATOM   2066 C  CG2 . VAL A 1 263 ? 149.046 164.183 126.890 1.00 67.28  0  262 VAL A CG2 1 
ATOM   2067 N  N   . ARG A 1 264 ? 151.140 161.818 123.843 1.00 67.28  0  263 ARG A N   1 
ATOM   2068 C  CA  . ARG A 1 264 ? 151.978 160.766 123.293 1.00 67.28  0  263 ARG A CA  1 
ATOM   2069 C  C   . ARG A 1 264 ? 151.313 160.146 122.074 1.00 67.28  0  263 ARG A C   1 
ATOM   2070 O  O   . ARG A 1 264 ? 150.088 160.148 121.933 1.00 67.28  0  263 ARG A O   1 
ATOM   2071 C  CB  . ARG A 1 264 ? 152.269 159.688 124.342 1.00 67.28  0  263 ARG A CB  1 
ATOM   2072 C  CG  . ARG A 1 264 ? 151.055 159.279 125.153 1.00 67.28  0  263 ARG A CG  1 
ATOM   2073 C  CD  . ARG A 1 264 ? 151.448 158.422 126.340 1.00 67.28  0  263 ARG A CD  1 
ATOM   2074 N  NE  . ARG A 1 264 ? 150.327 157.637 126.841 1.00 67.28  0  263 ARG A NE  1 
ATOM   2075 C  CZ  . ARG A 1 264 ? 150.173 157.282 128.109 1.00 67.28  0  263 ARG A CZ  1 
ATOM   2076 N  NH1 . ARG A 1 264 ? 151.052 157.629 129.034 1.00 67.28  1  263 ARG A NH1 1 
ATOM   2077 N  NH2 . ARG A 1 264 ? 149.108 156.567 128.458 1.00 67.28  0  263 ARG A NH2 1 
ATOM   2078 N  N   . VAL A 1 265 ? 152.153 159.610 121.193 1.00 67.28  0  264 VAL A N   1 
ATOM   2079 C  CA  . VAL A 1 265 ? 151.722 158.877 120.009 1.00 67.28  0  264 VAL A CA  1 
ATOM   2080 C  C   . VAL A 1 265 ? 152.544 157.599 119.934 1.00 67.28  0  264 VAL A C   1 
ATOM   2081 O  O   . VAL A 1 265 ? 153.771 157.637 120.069 1.00 67.28  0  264 VAL A O   1 
ATOM   2082 C  CB  . VAL A 1 265 ? 151.891 159.709 118.723 1.00 67.28  0  264 VAL A CB  1 
ATOM   2083 C  CG1 . VAL A 1 265 ? 151.868 158.809 117.500 1.00 67.28  0  264 VAL A CG1 1 
ATOM   2084 C  CG2 . VAL A 1 265 ? 150.804 160.767 118.631 1.00 67.28  0  264 VAL A CG2 1 
ATOM   2085 N  N   . PHE A 1 266 ? 151.873 156.468 119.717 1.00 67.28  0  265 PHE A N   1 
ATOM   2086 C  CA  . PHE A 1 266 ? 152.520 155.164 119.723 1.00 67.28  0  265 PHE A CA  1 
ATOM   2087 C  C   . PHE A 1 266 ? 152.826 154.654 118.319 1.00 67.28  0  265 PHE A C   1 
ATOM   2088 O  O   . PHE A 1 266 ? 153.132 153.468 118.151 1.00 67.28  0  265 PHE A O   1 
ATOM   2089 C  CB  . PHE A 1 266 ? 151.655 154.155 120.478 1.00 67.28  0  265 PHE A CB  1 
ATOM   2090 C  CG  . PHE A 1 266 ? 151.808 154.223 121.971 1.00 67.28  0  265 PHE A CG  1 
ATOM   2091 C  CD1 . PHE A 1 266 ? 151.027 155.084 122.721 1.00 67.28  0  265 PHE A CD1 1 
ATOM   2092 C  CD2 . PHE A 1 266 ? 152.728 153.422 122.624 1.00 67.28  0  265 PHE A CD2 1 
ATOM   2093 C  CE1 . PHE A 1 266 ? 151.162 155.149 124.093 1.00 67.28  0  265 PHE A CE1 1 
ATOM   2094 C  CE2 . PHE A 1 266 ? 152.867 153.482 123.997 1.00 67.28  0  265 PHE A CE2 1 
ATOM   2095 C  CZ  . PHE A 1 266 ? 152.083 154.347 124.731 1.00 67.28  0  265 PHE A CZ  1 
ATOM   2096 N  N   . ASP A 1 267 ? 152.751 155.519 117.309 1.00 67.28  0  266 ASP A N   1 
ATOM   2097 C  CA  . ASP A 1 267 ? 153.061 155.149 115.933 1.00 67.28  0  266 ASP A CA  1 
ATOM   2098 C  C   . ASP A 1 267 ? 154.162 156.059 115.412 1.00 67.28  0  266 ASP A C   1 
ATOM   2099 O  O   . ASP A 1 267 ? 154.019 157.288 115.429 1.00 67.28  0  266 ASP A O   1 
ATOM   2100 C  CB  . ASP A 1 267 ? 151.820 155.240 115.041 1.00 67.28  0  266 ASP A CB  1 
ATOM   2101 C  CG  . ASP A 1 267 ? 151.879 154.287 113.864 1.00 67.28  0  266 ASP A CG  1 
ATOM   2102 O  OD1 . ASP A 1 267 ? 152.987 154.061 113.334 1.00 67.28  0  266 ASP A OD1 1 
ATOM   2103 O  OD2 . ASP A 1 267 ? 150.817 153.762 113.469 1.00 67.28  -1 266 ASP A OD2 1 
ATOM   2104 N  N   . ARG A 1 268 ? 155.255 155.452 114.941 1.00 67.28  0  267 ARG A N   1 
ATOM   2105 C  CA  . ARG A 1 268 ? 156.388 156.234 114.461 1.00 67.28  0  267 ARG A CA  1 
ATOM   2106 C  C   . ARG A 1 268 ? 156.013 157.063 113.240 1.00 67.28  0  267 ARG A C   1 
ATOM   2107 O  O   . ARG A 1 268 ? 156.438 158.214 113.111 1.00 67.28  0  267 ARG A O   1 
ATOM   2108 C  CB  . ARG A 1 268 ? 157.570 155.318 114.143 1.00 67.28  0  267 ARG A CB  1 
ATOM   2109 C  CG  . ARG A 1 268 ? 158.850 156.069 113.802 1.00 67.28  0  267 ARG A CG  1 
ATOM   2110 C  CD  . ARG A 1 268 ? 159.953 155.133 113.334 1.00 67.28  0  267 ARG A CD  1 
ATOM   2111 N  NE  . ARG A 1 268 ? 160.438 154.276 114.410 1.00 67.28  0  267 ARG A NE  1 
ATOM   2112 C  CZ  . ARG A 1 268 ? 160.117 152.998 114.552 1.00 67.28  0  267 ARG A CZ  1 
ATOM   2113 N  NH1 . ARG A 1 268 ? 159.307 152.389 113.702 1.00 67.28  1  267 ARG A NH1 1 
ATOM   2114 N  NH2 . ARG A 1 268 ? 160.621 152.313 115.575 1.00 67.28  0  267 ARG A NH2 1 
ATOM   2115 N  N   . GLU A 1 269 ? 155.218 156.496 112.331 1.00 67.28  0  268 GLU A N   1 
ATOM   2116 C  CA  . GLU A 1 269 ? 154.834 157.235 111.132 1.00 67.28  0  268 GLU A CA  1 
ATOM   2117 C  C   . GLU A 1 269 ? 153.899 158.393 111.468 1.00 67.28  0  268 GLU A C   1 
ATOM   2118 O  O   . GLU A 1 269 ? 153.993 159.469 110.864 1.00 67.28  0  268 GLU A O   1 
ATOM   2119 C  CB  . GLU A 1 269 ? 154.195 156.286 110.120 1.00 67.28  0  268 GLU A CB  1 
ATOM   2120 C  CG  . GLU A 1 269 ? 155.157 155.233 109.589 1.00 67.28  0  268 GLU A CG  1 
ATOM   2121 C  CD  . GLU A 1 269 ? 154.510 154.289 108.595 1.00 67.28  0  268 GLU A CD  1 
ATOM   2122 O  OE1 . GLU A 1 269 ? 153.278 154.364 108.412 1.00 67.28  0  268 GLU A OE1 1 
ATOM   2123 O  OE2 . GLU A 1 269 ? 155.237 153.470 107.994 1.00 67.28  -1 268 GLU A OE2 1 
ATOM   2124 N  N   . ILE A 1 270 ? 152.993 158.195 112.428 1.00 67.28  0  269 ILE A N   1 
ATOM   2125 C  CA  . ILE A 1 270 ? 152.129 159.286 112.866 1.00 67.28  0  269 ILE A CA  1 
ATOM   2126 C  C   . ILE A 1 270 ? 152.956 160.393 113.509 1.00 67.28  0  269 ILE A C   1 
ATOM   2127 O  O   . ILE A 1 270 ? 152.731 161.586 113.258 1.00 67.28  0  269 ILE A O   1 
ATOM   2128 C  CB  . ILE A 1 270 ? 151.041 158.759 113.818 1.00 67.28  0  269 ILE A CB  1 
ATOM   2129 C  CG1 . ILE A 1 270 ? 150.061 157.861 113.065 1.00 67.28  0  269 ILE A CG1 1 
ATOM   2130 C  CG2 . ILE A 1 270 ? 150.285 159.908 114.453 1.00 67.28  0  269 ILE A CG2 1 
ATOM   2131 C  CD1 . ILE A 1 270 ? 148.977 157.274 113.939 1.00 67.28  0  269 ILE A CD1 1 
ATOM   2132 N  N   . ALA A 1 271 ? 153.929 160.022 114.344 1.00 67.28  0  270 ALA A N   1 
ATOM   2133 C  CA  . ALA A 1 271 ? 154.812 161.027 114.927 1.00 67.28  0  270 ALA A CA  1 
ATOM   2134 C  C   . ALA A 1 271 ? 155.597 161.762 113.847 1.00 67.28  0  270 ALA A C   1 
ATOM   2135 O  O   . ALA A 1 271 ? 155.788 162.982 113.926 1.00 67.28  0  270 ALA A O   1 
ATOM   2136 C  CB  . ALA A 1 271 ? 155.761 160.374 115.930 1.00 67.28  0  270 ALA A CB  1 
ATOM   2137 N  N   . GLN A 1 272 ? 156.057 161.033 112.828 1.00 67.28  0  271 GLN A N   1 
ATOM   2138 C  CA  . GLN A 1 272 ? 156.821 161.651 111.750 1.00 67.28  0  271 GLN A CA  1 
ATOM   2139 C  C   . GLN A 1 272 ? 155.974 162.644 110.966 1.00 67.28  0  271 GLN A C   1 
ATOM   2140 O  O   . GLN A 1 272 ? 156.444 163.737 110.633 1.00 67.28  0  271 GLN A O   1 
ATOM   2141 C  CB  . GLN A 1 272 ? 157.380 160.573 110.823 1.00 67.28  0  271 GLN A CB  1 
ATOM   2142 C  CG  . GLN A 1 272 ? 158.450 161.069 109.866 1.00 67.28  0  271 GLN A CG  1 
ATOM   2143 C  CD  . GLN A 1 272 ? 159.759 161.370 110.565 1.00 67.28  0  271 GLN A CD  1 
ATOM   2144 O  OE1 . GLN A 1 272 ? 160.353 162.430 110.367 1.00 67.28  0  271 GLN A OE1 1 
ATOM   2145 N  NE2 . GLN A 1 272 ? 160.218 160.435 111.388 1.00 67.28  0  271 GLN A NE2 1 
ATOM   2146 N  N   . MET A 1 273 ? 154.723 162.289 110.662 1.00 67.98  0  272 MET A N   1 
ATOM   2147 C  CA  . MET A 1 273 ? 153.879 163.228 109.928 1.00 67.98  0  272 MET A CA  1 
ATOM   2148 C  C   . MET A 1 273 ? 153.508 164.430 110.788 1.00 67.98  0  272 MET A C   1 
ATOM   2149 O  O   . MET A 1 273 ? 153.402 165.548 110.270 1.00 67.98  0  272 MET A O   1 
ATOM   2150 C  CB  . MET A 1 273 ? 152.619 162.541 109.399 1.00 67.98  0  272 MET A CB  1 
ATOM   2151 C  CG  . MET A 1 273 ? 151.667 162.041 110.459 1.00 67.98  0  272 MET A CG  1 
ATOM   2152 S  SD  . MET A 1 273 ? 150.207 161.267 109.756 1.00 67.98  0  272 MET A SD  1 
ATOM   2153 C  CE  . MET A 1 273 ? 149.352 162.704 109.128 1.00 67.98  0  272 MET A CE  1 
ATOM   2154 N  N   . PHE A 1 274 ? 153.317 164.230 112.096 1.00 67.28  0  273 PHE A N   1 
ATOM   2155 C  CA  . PHE A 1 274 ? 153.040 165.369 112.965 1.00 67.28  0  273 PHE A CA  1 
ATOM   2156 C  C   . PHE A 1 274 ? 154.249 166.288 113.090 1.00 67.28  0  273 PHE A C   1 
ATOM   2157 O  O   . PHE A 1 274 ? 154.085 167.504 113.240 1.00 67.28  0  273 PHE A O   1 
ATOM   2158 C  CB  . PHE A 1 274 ? 152.580 164.886 114.340 1.00 67.28  0  273 PHE A CB  1 
ATOM   2159 C  CG  . PHE A 1 274 ? 151.125 164.516 114.394 1.00 67.28  0  273 PHE A CG  1 
ATOM   2160 C  CD1 . PHE A 1 274 ? 150.197 165.201 113.629 1.00 67.28  0  273 PHE A CD1 1 
ATOM   2161 C  CD2 . PHE A 1 274 ? 150.685 163.484 115.203 1.00 67.28  0  273 PHE A CD2 1 
ATOM   2162 C  CE1 . PHE A 1 274 ? 148.858 164.867 113.675 1.00 67.28  0  273 PHE A CE1 1 
ATOM   2163 C  CE2 . PHE A 1 274 ? 149.347 163.148 115.254 1.00 67.28  0  273 PHE A CE2 1 
ATOM   2164 C  CZ  . PHE A 1 274 ? 148.433 163.838 114.488 1.00 67.28  0  273 PHE A CZ  1 
ATOM   2165 N  N   . LEU A 1 275 ? 155.464 165.736 113.035 1.00 67.28  0  274 LEU A N   1 
ATOM   2166 C  CA  . LEU A 1 275 ? 156.648 166.589 113.015 1.00 67.28  0  274 LEU A CA  1 
ATOM   2167 C  C   . LEU A 1 275 ? 156.785 167.310 111.680 1.00 67.28  0  274 LEU A C   1 
ATOM   2168 O  O   . LEU A 1 275 ? 157.190 168.478 111.638 1.00 67.28  0  274 LEU A O   1 
ATOM   2169 C  CB  . LEU A 1 275 ? 157.906 165.774 113.306 1.00 67.28  0  274 LEU A CB  1 
ATOM   2170 C  CG  . LEU A 1 275 ? 159.107 166.625 113.728 1.00 67.28  0  274 LEU A CG  1 
ATOM   2171 C  CD1 . LEU A 1 275 ? 158.919 167.160 115.141 1.00 67.28  0  274 LEU A CD1 1 
ATOM   2172 C  CD2 . LEU A 1 275 ? 160.414 165.858 113.603 1.00 67.28  0  274 LEU A CD2 1 
ATOM   2173 N  N   . ASN A 1 276 ? 156.464 166.627 110.579 1.00 67.28  0  275 ASN A N   1 
ATOM   2174 C  CA  . ASN A 1 276 ? 156.480 167.277 109.273 1.00 67.28  0  275 ASN A CA  1 
ATOM   2175 C  C   . ASN A 1 276 ? 155.458 168.402 109.203 1.00 67.28  0  275 ASN A C   1 
ATOM   2176 O  O   . ASN A 1 276 ? 155.657 169.380 108.473 1.00 67.28  0  275 ASN A O   1 
ATOM   2177 C  CB  . ASN A 1 276 ? 156.221 166.250 108.171 1.00 67.28  0  275 ASN A CB  1 
ATOM   2178 C  CG  . ASN A 1 276 ? 157.345 165.243 108.037 1.00 67.28  0  275 ASN A CG  1 
ATOM   2179 O  OD1 . ASN A 1 276 ? 158.232 165.169 108.887 1.00 67.28  0  275 ASN A OD1 1 
ATOM   2180 N  ND2 . ASN A 1 276 ? 157.314 164.462 106.965 1.00 67.28  0  275 ASN A ND2 1 
ATOM   2181 N  N   . MET A 1 277 ? 154.360 168.279 109.950 1.00 67.28  0  276 MET A N   1 
ATOM   2182 C  CA  . MET A 1 277 ? 153.397 169.367 110.065 1.00 67.28  0  276 MET A CA  1 
ATOM   2183 C  C   . MET A 1 277 ? 153.980 170.586 110.766 1.00 67.28  0  276 MET A C   1 
ATOM   2184 O  O   . MET A 1 277 ? 153.435 171.686 110.624 1.00 67.28  0  276 MET A O   1 
ATOM   2185 C  CB  . MET A 1 277 ? 152.165 168.900 110.841 1.00 67.28  0  276 MET A CB  1 
ATOM   2186 C  CG  . MET A 1 277 ? 151.121 168.142 110.043 1.00 67.28  0  276 MET A CG  1 
ATOM   2187 S  SD  . MET A 1 277 ? 149.740 167.698 111.119 1.00 67.28  0  276 MET A SD  1 
ATOM   2188 C  CE  . MET A 1 277 ? 149.125 166.215 110.334 1.00 67.28  0  276 MET A CE  1 
ATOM   2189 N  N   . THR A 1 278 ? 155.068 170.420 111.513 1.00 67.28  0  277 THR A N   1 
ATOM   2190 C  CA  . THR A 1 278 ? 155.495 171.408 112.496 1.00 67.28  0  277 THR A CA  1 
ATOM   2191 C  C   . THR A 1 278 ? 156.896 171.955 112.268 1.00 67.28  0  277 THR A C   1 
ATOM   2192 O  O   . THR A 1 278 ? 157.113 173.157 112.444 1.00 67.28  0  277 THR A O   1 
ATOM   2193 C  CB  . THR A 1 278 ? 155.416 170.791 113.902 1.00 67.28  0  277 THR A CB  1 
ATOM   2194 O  OG1 . THR A 1 278 ? 154.096 170.281 114.128 1.00 67.28  0  277 THR A OG1 1 
ATOM   2195 C  CG2 . THR A 1 278 ? 155.742 171.822 114.968 1.00 67.28  0  277 THR A CG2 1 
ATOM   2196 N  N   . LYS A 1 279 ? 157.856 171.113 111.876 1.00 67.28  0  278 LYS A N   1 
ATOM   2197 C  CA  . LYS A 1 279 ? 159.257 171.529 111.899 1.00 67.28  0  278 LYS A CA  1 
ATOM   2198 C  C   . LYS A 1 279 ? 159.548 172.652 110.909 1.00 67.28  0  278 LYS A C   1 
ATOM   2199 O  O   . LYS A 1 279 ? 160.467 173.447 111.137 1.00 67.28  0  278 LYS A O   1 
ATOM   2200 C  CB  . LYS A 1 279 ? 160.171 170.331 111.638 1.00 67.28  0  278 LYS A CB  1 
ATOM   2201 C  CG  . LYS A 1 279 ? 160.143 169.798 110.218 1.00 67.28  0  278 LYS A CG  1 
ATOM   2202 C  CD  . LYS A 1 279 ? 161.008 168.555 110.081 1.00 67.28  0  278 LYS A CD  1 
ATOM   2203 C  CE  . LYS A 1 279 ? 161.255 168.210 108.622 1.00 67.28  0  278 LYS A CE  1 
ATOM   2204 N  NZ  . LYS A 1 279 ? 160.066 167.578 107.989 1.00 67.28  1  278 LYS A NZ  1 
ATOM   2205 N  N   . LEU A 1 280 ? 158.790 172.742 109.814 1.00 69.16  0  279 LEU A N   1 
ATOM   2206 C  CA  . LEU A 1 280 ? 159.022 173.820 108.857 1.00 69.16  0  279 LEU A CA  1 
ATOM   2207 C  C   . LEU A 1 280 ? 158.532 175.163 109.385 1.00 69.16  0  279 LEU A C   1 
ATOM   2208 O  O   . LEU A 1 280 ? 159.105 176.205 109.045 1.00 69.16  0  279 LEU A O   1 
ATOM   2209 C  CB  . LEU A 1 280 ? 158.350 173.508 107.518 1.00 69.16  0  279 LEU A CB  1 
ATOM   2210 C  CG  . LEU A 1 280 ? 159.072 172.610 106.505 1.00 69.16  0  279 LEU A CG  1 
ATOM   2211 C  CD1 . LEU A 1 280 ? 160.363 173.267 106.032 1.00 69.16  0  279 LEU A CD1 1 
ATOM   2212 C  CD2 . LEU A 1 280 ? 159.337 171.210 107.041 1.00 69.16  0  279 LEU A CD2 1 
ATOM   2213 N  N   . GLU A 1 281 ? 157.484 175.163 110.205 1.00 70.59  0  280 GLU A N   1 
ATOM   2214 C  CA  . GLU A 1 281 ? 156.907 176.410 110.689 1.00 70.59  0  280 GLU A CA  1 
ATOM   2215 C  C   . GLU A 1 281 ? 157.882 177.147 111.599 1.00 70.59  0  280 GLU A C   1 
ATOM   2216 O  O   . GLU A 1 281 ? 158.626 176.533 112.369 1.00 70.59  0  280 GLU A O   1 
ATOM   2217 C  CB  . GLU A 1 281 ? 155.601 176.135 111.432 1.00 70.59  0  280 GLU A CB  1 
ATOM   2218 C  CG  . GLU A 1 281 ? 154.434 175.795 110.519 1.00 70.59  0  280 GLU A CG  1 
ATOM   2219 C  CD  . GLU A 1 281 ? 153.708 177.026 110.017 1.00 70.59  0  280 GLU A CD  1 
ATOM   2220 O  OE1 . GLU A 1 281 ? 154.077 178.146 110.429 1.00 70.59  0  280 GLU A OE1 1 
ATOM   2221 O  OE2 . GLU A 1 281 ? 152.769 176.875 109.208 1.00 70.59  -1 280 GLU A OE2 1 
ATOM   2222 N  N   . LYS A 1 282 ? 157.875 178.479 111.506 1.00 71.80  0  281 LYS A N   1 
ATOM   2223 C  CA  . LYS A 1 282 ? 158.780 179.324 112.277 1.00 71.80  0  281 LYS A CA  1 
ATOM   2224 C  C   . LYS A 1 282 ? 158.036 180.346 113.131 1.00 71.80  0  281 LYS A C   1 
ATOM   2225 O  O   . LYS A 1 282 ? 158.628 181.347 113.549 1.00 71.80  0  281 LYS A O   1 
ATOM   2226 C  CB  . LYS A 1 282 ? 159.770 180.029 111.347 1.00 71.80  0  281 LYS A CB  1 
ATOM   2227 C  CG  . LYS A 1 282 ? 159.128 181.013 110.383 1.00 71.80  0  281 LYS A CG  1 
ATOM   2228 C  CD  . LYS A 1 282 ? 160.172 181.690 109.509 1.00 71.80  0  281 LYS A CD  1 
ATOM   2229 C  CE  . LYS A 1 282 ? 160.719 180.734 108.461 1.00 71.80  0  281 LYS A CE  1 
ATOM   2230 N  NZ  . LYS A 1 282 ? 161.645 181.417 107.516 1.00 71.80  1  281 LYS A NZ  1 
ATOM   2231 N  N   . GLU A 1 283 ? 156.754 180.116 113.408 1.00 72.73  0  282 GLU A N   1 
ATOM   2232 C  CA  . GLU A 1 283 ? 155.963 181.024 114.224 1.00 72.73  0  282 GLU A CA  1 
ATOM   2233 C  C   . GLU A 1 283 ? 154.977 180.226 115.064 1.00 72.73  0  282 GLU A C   1 
ATOM   2234 O  O   . GLU A 1 283 ? 154.579 179.118 114.697 1.00 72.73  0  282 GLU A O   1 
ATOM   2235 C  CB  . GLU A 1 283 ? 155.201 182.044 113.366 1.00 72.73  0  282 GLU A CB  1 
ATOM   2236 C  CG  . GLU A 1 283 ? 156.041 183.215 112.886 1.00 72.73  0  282 GLU A CG  1 
ATOM   2237 C  CD  . GLU A 1 283 ? 155.267 184.518 112.877 1.00 72.73  0  282 GLU A CD  1 
ATOM   2238 O  OE1 . GLU A 1 283 ? 154.019 184.471 112.884 1.00 72.73  0  282 GLU A OE1 1 
ATOM   2239 O  OE2 . GLU A 1 283 ? 155.907 185.591 112.862 1.00 72.73  -1 282 GLU A OE2 1 
ATOM   2240 N  N   . ALA A 1 284 ? 154.586 180.802 116.200 1.00 71.04  0  283 ALA A N   1 
ATOM   2241 C  CA  . ALA A 1 284 ? 153.556 180.232 117.057 1.00 71.04  0  283 ALA A CA  1 
ATOM   2242 C  C   . ALA A 1 284 ? 152.544 181.317 117.385 1.00 71.04  0  283 ALA A C   1 
ATOM   2243 O  O   . ALA A 1 284 ? 152.924 182.416 117.799 1.00 71.04  0  283 ALA A O   1 
ATOM   2244 C  CB  . ALA A 1 284 ? 154.155 179.653 118.342 1.00 71.04  0  283 ALA A CB  1 
ATOM   2245 N  N   . GLN A 1 285 ? 151.263 181.013 117.202 1.00 69.60  0  284 GLN A N   1 
ATOM   2246 C  CA  . GLN A 1 285 ? 150.192 181.982 117.407 1.00 69.60  0  284 GLN A CA  1 
ATOM   2247 C  C   . GLN A 1 285 ? 149.417 181.611 118.663 1.00 69.60  0  284 GLN A C   1 
ATOM   2248 O  O   . GLN A 1 285 ? 148.828 180.531 118.733 1.00 69.60  0  284 GLN A O   1 
ATOM   2249 C  CB  . GLN A 1 285 ? 149.259 182.029 116.197 1.00 69.60  0  284 GLN A CB  1 
ATOM   2250 C  CG  . GLN A 1 285 ? 149.902 182.569 114.931 1.00 69.60  0  284 GLN A CG  1 
ATOM   2251 C  CD  . GLN A 1 285 ? 150.709 181.519 114.192 1.00 69.60  0  284 GLN A CD  1 
ATOM   2252 O  OE1 . GLN A 1 285 ? 150.552 180.321 114.426 1.00 69.60  0  284 GLN A OE1 1 
ATOM   2253 N  NE2 . GLN A 1 285 ? 151.579 181.966 113.294 1.00 69.60  0  284 GLN A NE2 1 
ATOM   2254 N  N   . VAL A 1 286 ? 149.409 182.507 119.648 1.00 68.60  0  285 VAL A N   1 
ATOM   2255 C  CA  . VAL A 1 286 ? 148.675 182.243 120.878 1.00 68.60  0  285 VAL A CA  1 
ATOM   2256 C  C   . VAL A 1 286 ? 147.177 182.304 120.604 1.00 68.60  0  285 VAL A C   1 
ATOM   2257 O  O   . VAL A 1 286 ? 146.699 183.147 119.831 1.00 68.60  0  285 VAL A O   1 
ATOM   2258 C  CB  . VAL A 1 286 ? 149.100 183.230 121.979 1.00 68.60  0  285 VAL A CB  1 
ATOM   2259 C  CG1 . VAL A 1 286 ? 148.718 184.642 121.605 1.00 68.60  0  285 VAL A CG1 1 
ATOM   2260 C  CG2 . VAL A 1 286 ? 148.470 182.846 123.307 1.00 68.60  0  285 VAL A CG2 1 
ATOM   2261 N  N   . GLU A 1 287 ? 146.429 181.386 121.215 1.00 69.09  0  286 GLU A N   1 
ATOM   2262 C  CA  . GLU A 1 287 ? 144.993 181.279 120.992 1.00 69.09  0  286 GLU A CA  1 
ATOM   2263 C  C   . GLU A 1 287 ? 144.185 181.621 122.237 1.00 69.09  0  286 GLU A C   1 
ATOM   2264 O  O   . GLU A 1 287 ? 143.309 182.488 122.184 1.00 69.09  0  286 GLU A O   1 
ATOM   2265 C  CB  . GLU A 1 287 ? 144.637 179.870 120.501 1.00 69.09  0  286 GLU A CB  1 
ATOM   2266 C  CG  . GLU A 1 287 ? 144.643 179.720 118.990 1.00 69.09  0  286 GLU A CG  1 
ATOM   2267 C  CD  . GLU A 1 287 ? 143.870 178.503 118.523 1.00 69.09  0  286 GLU A CD  1 
ATOM   2268 O  OE1 . GLU A 1 287 ? 143.334 177.773 119.383 1.00 69.09  0  286 GLU A OE1 1 
ATOM   2269 O  OE2 . GLU A 1 287 ? 143.803 178.273 117.298 1.00 69.09  -1 286 GLU A OE2 1 
ATOM   2270 N  N   . ALA A 1 288 ? 144.448 180.958 123.361 1.00 67.28  0  287 ALA A N   1 
ATOM   2271 C  CA  . ALA A 1 288 ? 143.666 181.150 124.575 1.00 67.28  0  287 ALA A CA  1 
ATOM   2272 C  C   . ALA A 1 288 ? 144.594 181.335 125.765 1.00 67.28  0  287 ALA A C   1 
ATOM   2273 O  O   . ALA A 1 288 ? 145.567 180.590 125.921 1.00 67.28  0  287 ALA A O   1 
ATOM   2274 C  CB  . ALA A 1 288 ? 142.727 179.964 124.819 1.00 67.28  0  287 ALA A CB  1 
ATOM   2275 N  N   . THR A 1 289 ? 144.290 182.328 126.597 1.00 67.28  0  288 THR A N   1 
ATOM   2276 C  CA  . THR A 1 289 ? 144.999 182.572 127.846 1.00 67.28  0  288 THR A CA  1 
ATOM   2277 C  C   . THR A 1 289 ? 143.985 182.604 128.979 1.00 67.28  0  288 THR A C   1 
ATOM   2278 O  O   . THR A 1 289 ? 142.953 183.275 128.872 1.00 67.28  0  288 THR A O   1 
ATOM   2279 C  CB  . THR A 1 289 ? 145.780 183.888 127.800 1.00 67.28  0  288 THR A CB  1 
ATOM   2280 O  OG1 . THR A 1 289 ? 144.865 184.986 127.692 1.00 67.28  0  288 THR A OG1 1 
ATOM   2281 C  CG2 . THR A 1 289 ? 146.730 183.907 126.613 1.00 67.28  0  288 THR A CG2 1 
ATOM   2282 N  N   . SER A 1 290 ? 144.277 181.884 130.060 1.00 67.28  0  289 SER A N   1 
ATOM   2283 C  CA  . SER A 1 290 ? 143.351 181.770 131.181 1.00 67.28  0  289 SER A CA  1 
ATOM   2284 C  C   . SER A 1 290 ? 144.123 181.882 132.484 1.00 67.28  0  289 SER A C   1 
ATOM   2285 O  O   . SER A 1 290 ? 145.058 181.111 132.722 1.00 67.28  0  289 SER A O   1 
ATOM   2286 C  CB  . SER A 1 290 ? 142.582 180.447 131.127 1.00 67.28  0  289 SER A CB  1 
ATOM   2287 O  OG  . SER A 1 290 ? 143.436 179.352 131.410 1.00 67.28  0  289 SER A OG  1 
ATOM   2288 N  N   . ARG A 1 291 ? 143.731 182.836 133.324 1.00 67.28  0  290 ARG A N   1 
ATOM   2289 C  CA  . ARG A 1 291 ? 144.293 183.016 134.662 1.00 67.28  0  290 ARG A CA  1 
ATOM   2290 C  C   . ARG A 1 291 ? 143.146 182.849 135.654 1.00 67.28  0  290 ARG A C   1 
ATOM   2291 O  O   . ARG A 1 291 ? 142.500 183.824 136.044 1.00 67.28  0  290 ARG A O   1 
ATOM   2292 C  CB  . ARG A 1 291 ? 144.971 184.378 134.806 1.00 67.28  0  290 ARG A CB  1 
ATOM   2293 C  CG  . ARG A 1 291 ? 145.571 184.916 133.519 1.00 67.28  0  290 ARG A CG  1 
ATOM   2294 C  CD  . ARG A 1 291 ? 146.652 185.945 133.805 1.00 67.28  0  290 ARG A CD  1 
ATOM   2295 N  NE  . ARG A 1 291 ? 147.896 185.325 134.245 1.00 67.28  0  290 ARG A NE  1 
ATOM   2296 C  CZ  . ARG A 1 291 ? 148.756 185.886 135.084 1.00 67.28  0  290 ARG A CZ  1 
ATOM   2297 N  NH1 . ARG A 1 291 ? 148.539 187.086 135.597 1.00 67.28  1  290 ARG A NH1 1 
ATOM   2298 N  NH2 . ARG A 1 291 ? 149.863 185.227 135.415 1.00 67.28  0  290 ARG A NH2 1 
ATOM   2299 N  N   . LYS A 1 292 ? 142.898 181.609 136.063 1.00 67.28  0  291 LYS A N   1 
ATOM   2300 C  CA  . LYS A 1 292 ? 141.793 181.281 136.948 1.00 67.28  0  291 LYS A CA  1 
ATOM   2301 C  C   . LYS A 1 292 ? 142.310 180.942 138.340 1.00 67.28  0  291 LYS A C   1 
ATOM   2302 O  O   . LYS A 1 292 ? 143.353 180.301 138.497 1.00 67.28  0  291 LYS A O   1 
ATOM   2303 C  CB  . LYS A 1 292 ? 140.973 180.110 136.396 1.00 67.28  0  291 LYS A CB  1 
ATOM   2304 C  CG  . LYS A 1 292 ? 141.788 178.870 136.076 1.00 67.28  0  291 LYS A CG  1 
ATOM   2305 C  CD  . LYS A 1 292 ? 140.928 177.787 135.440 1.00 67.28  0  291 LYS A CD  1 
ATOM   2306 C  CE  . LYS A 1 292 ? 139.980 178.365 134.401 1.00 67.28  0  291 LYS A CE  1 
ATOM   2307 N  NZ  . LYS A 1 292 ? 139.450 177.316 133.487 1.00 67.28  1  291 LYS A NZ  1 
ATOM   2308 N  N   . GLU A 1 293 ? 141.570 181.390 139.350 1.00 67.28  0  292 GLU A N   1 
ATOM   2309 C  CA  . GLU A 1 293 ? 141.929 181.152 140.740 1.00 67.28  0  292 GLU A CA  1 
ATOM   2310 C  C   . GLU A 1 293 ? 141.483 179.757 141.153 1.00 67.28  0  292 GLU A C   1 
ATOM   2311 O  O   . GLU A 1 293 ? 140.360 179.341 140.850 1.00 67.28  0  292 GLU A O   1 
ATOM   2312 C  CB  . GLU A 1 293 ? 141.293 182.204 141.648 1.00 67.28  0  292 GLU A CB  1 
ATOM   2313 C  CG  . GLU A 1 293 ? 142.045 182.442 142.945 1.00 67.28  0  292 GLU A CG  1 
ATOM   2314 C  CD  . GLU A 1 293 ? 141.772 183.811 143.534 1.00 67.28  0  292 GLU A CD  1 
ATOM   2315 O  OE1 . GLU A 1 293 ? 142.357 184.799 143.043 1.00 67.28  0  292 GLU A OE1 1 
ATOM   2316 O  OE2 . GLU A 1 293 ? 140.972 183.899 144.489 1.00 67.28  -1 292 GLU A OE2 1 
ATOM   2317 N  N   . LYS A 1 294 ? 142.365 179.039 141.843 1.00 67.28  0  293 LYS A N   1 
ATOM   2318 C  CA  . LYS A 1 294 ? 142.080 177.695 142.317 1.00 67.28  0  293 LYS A CA  1 
ATOM   2319 C  C   . LYS A 1 294 ? 142.518 177.571 143.768 1.00 67.28  0  293 LYS A C   1 
ATOM   2320 O  O   . LYS A 1 294 ? 143.363 178.329 144.252 1.00 67.28  0  293 LYS A O   1 
ATOM   2321 C  CB  . LYS A 1 294 ? 142.780 176.632 141.460 1.00 67.28  0  293 LYS A CB  1 
ATOM   2322 C  CG  . LYS A 1 294 ? 142.139 176.408 140.103 1.00 67.28  0  293 LYS A CG  1 
ATOM   2323 C  CD  . LYS A 1 294 ? 142.781 175.238 139.378 1.00 67.28  0  293 LYS A CD  1 
ATOM   2324 C  CE  . LYS A 1 294 ? 141.735 174.354 138.723 1.00 67.28  0  293 LYS A CE  1 
ATOM   2325 N  NZ  . LYS A 1 294 ? 140.881 175.121 137.775 1.00 67.28  1  293 LYS A NZ  1 
ATOM   2326 N  N   . ALA A 1 295 ? 141.931 176.599 144.461 1.00 67.28  0  294 ALA A N   1 
ATOM   2327 C  CA  . ALA A 1 295 ? 142.201 176.376 145.874 1.00 67.28  0  294 ALA A CA  1 
ATOM   2328 C  C   . ALA A 1 295 ? 142.615 174.930 146.091 1.00 67.28  0  294 ALA A C   1 
ATOM   2329 O  O   . ALA A 1 295 ? 141.954 174.010 145.599 1.00 67.28  0  294 ALA A O   1 
ATOM   2330 C  CB  . ALA A 1 295 ? 140.975 176.708 146.730 1.00 67.28  0  294 ALA A CB  1 
ATOM   2331 N  N   . LYS A 1 296 ? 143.708 174.734 146.824 1.00 67.28  0  295 LYS A N   1 
ATOM   2332 C  CA  . LYS A 1 296 ? 144.145 173.406 147.232 1.00 67.28  0  295 LYS A CA  1 
ATOM   2333 C  C   . LYS A 1 296 ? 143.550 173.106 148.603 1.00 67.28  0  295 LYS A C   1 
ATOM   2334 O  O   . LYS A 1 296 ? 143.787 173.847 149.563 1.00 67.28  0  295 LYS A O   1 
ATOM   2335 C  CB  . LYS A 1 296 ? 145.670 173.320 147.264 1.00 67.28  0  295 LYS A CB  1 
ATOM   2336 C  CG  . LYS A 1 296 ? 146.209 172.033 147.864 1.00 67.28  0  295 LYS A CG  1 
ATOM   2337 C  CD  . LYS A 1 296 ? 147.728 172.038 147.916 1.00 67.28  0  295 LYS A CD  1 
ATOM   2338 C  CE  . LYS A 1 296 ? 148.327 171.526 146.618 1.00 67.28  0  295 LYS A CE  1 
ATOM   2339 N  NZ  . LYS A 1 296 ? 149.788 171.268 146.742 1.00 67.28  1  295 LYS A NZ  1 
ATOM   2340 N  N   . GLN A 1 297 ? 142.777 172.028 148.690 1.00 67.28  0  296 GLN A N   1 
ATOM   2341 C  CA  . GLN A 1 297 ? 142.005 171.755 149.893 1.00 67.28  0  296 GLN A CA  1 
ATOM   2342 C  C   . GLN A 1 297 ? 142.904 171.325 151.046 1.00 67.28  0  296 GLN A C   1 
ATOM   2343 O  O   . GLN A 1 297 ? 143.984 170.760 150.851 1.00 67.28  0  296 GLN A O   1 
ATOM   2344 C  CB  . GLN A 1 297 ? 140.960 170.675 149.620 1.00 67.28  0  296 GLN A CB  1 
ATOM   2345 C  CG  . GLN A 1 297 ? 139.868 171.096 148.654 1.00 67.28  0  296 GLN A CG  1 
ATOM   2346 C  CD  . GLN A 1 297 ? 138.862 169.993 148.396 1.00 67.28  0  296 GLN A CD  1 
ATOM   2347 O  OE1 . GLN A 1 297 ? 139.010 168.875 148.889 1.00 67.28  0  296 GLN A OE1 1 
ATOM   2348 N  NE2 . GLN A 1 297 ? 137.831 170.302 147.619 1.00 67.28  0  296 GLN A NE2 1 
ATOM   2349 N  N   . ARG A 1 298 ? 142.442 171.606 152.261 1.00 67.28  0  297 ARG A N   1 
ATOM   2350 C  CA  . ARG A 1 298 ? 143.142 171.167 153.454 1.00 67.28  0  297 ARG A CA  1 
ATOM   2351 C  C   . ARG A 1 298 ? 143.051 169.648 153.586 1.00 67.28  0  297 ARG A C   1 
ATOM   2352 O  O   . ARG A 1 298 ? 142.104 169.030 153.094 1.00 67.28  0  297 ARG A O   1 
ATOM   2353 C  CB  . ARG A 1 298 ? 142.544 171.820 154.696 1.00 67.28  0  297 ARG A CB  1 
ATOM   2354 C  CG  . ARG A 1 298 ? 142.568 173.331 154.690 1.00 67.28  0  297 ARG A CG  1 
ATOM   2355 C  CD  . ARG A 1 298 ? 141.870 173.884 155.916 1.00 67.28  0  297 ARG A CD  1 
ATOM   2356 N  NE  . ARG A 1 298 ? 140.504 173.389 156.037 1.00 67.28  0  297 ARG A NE  1 
ATOM   2357 C  CZ  . ARG A 1 298 ? 139.456 173.927 155.428 1.00 67.28  0  297 ARG A CZ  1 
ATOM   2358 N  NH1 . ARG A 1 298 ? 139.583 174.973 154.629 1.00 67.28  1  297 ARG A NH1 1 
ATOM   2359 N  NH2 . ARG A 1 298 ? 138.252 173.398 155.623 1.00 67.28  0  297 ARG A NH2 1 
ATOM   2360 N  N   . PRO A 1 299 ? 144.025 169.022 154.240 1.00 67.28  0  298 PRO A N   1 
ATOM   2361 C  CA  . PRO A 1 299 ? 143.891 167.597 154.547 1.00 67.28  0  298 PRO A CA  1 
ATOM   2362 C  C   . PRO A 1 299 ? 142.815 167.369 155.594 1.00 67.28  0  298 PRO A C   1 
ATOM   2363 O  O   . PRO A 1 299 ? 142.560 168.218 156.452 1.00 67.28  0  298 PRO A O   1 
ATOM   2364 C  CB  . PRO A 1 299 ? 145.276 167.212 155.074 1.00 67.28  0  298 PRO A CB  1 
ATOM   2365 C  CG  . PRO A 1 299 ? 145.831 168.474 155.618 1.00 67.28  0  298 PRO A CG  1 
ATOM   2366 C  CD  . PRO A 1 299 ? 145.253 169.602 154.811 1.00 67.28  0  298 PRO A CD  1 
ATOM   2367 N  N   . LEU A 1 300 ? 142.172 166.209 155.511 1.00 67.28  0  299 LEU A N   1 
ATOM   2368 C  CA  . LEU A 1 300 ? 141.171 165.842 156.498 1.00 67.28  0  299 LEU A CA  1 
ATOM   2369 C  C   . LEU A 1 300 ? 141.848 165.494 157.822 1.00 67.28  0  299 LEU A C   1 
ATOM   2370 O  O   . LEU A 1 300 ? 143.074 165.531 157.958 1.00 67.28  0  299 LEU A O   1 
ATOM   2371 C  CB  . LEU A 1 300 ? 140.324 164.677 155.992 1.00 67.28  0  299 LEU A CB  1 
ATOM   2372 C  CG  . LEU A 1 300 ? 139.520 164.915 154.714 1.00 67.28  0  299 LEU A CG  1 
ATOM   2373 C  CD1 . LEU A 1 300 ? 140.219 164.295 153.515 1.00 67.28  0  299 LEU A CD1 1 
ATOM   2374 C  CD2 . LEU A 1 300 ? 138.112 164.365 154.862 1.00 67.28  0  299 LEU A CD2 1 
ATOM   2375 N  N   . ALA A 1 301 ? 141.032 165.152 158.814 1.00 67.28  0  300 ALA A N   1 
ATOM   2376 C  CA  . ALA A 1 301 ? 141.564 164.751 160.106 1.00 67.28  0  300 ALA A CA  1 
ATOM   2377 C  C   . ALA A 1 301 ? 142.369 163.463 159.971 1.00 67.28  0  300 ALA A C   1 
ATOM   2378 O  O   . ALA A 1 301 ? 142.081 162.608 159.129 1.00 67.28  0  300 ALA A O   1 
ATOM   2379 C  CB  . ALA A 1 301 ? 140.432 164.565 161.113 1.00 67.28  0  300 ALA A CB  1 
ATOM   2380 N  N   . LEU A 1 302 ? 143.392 163.333 160.810 1.00 67.28  0  301 LEU A N   1 
ATOM   2381 C  CA  . LEU A 1 302 ? 144.328 162.222 160.701 1.00 67.28  0  301 LEU A CA  1 
ATOM   2382 C  C   . LEU A 1 302 ? 143.738 160.973 161.343 1.00 67.28  0  301 LEU A C   1 
ATOM   2383 O  O   . LEU A 1 302 ? 143.359 160.991 162.519 1.00 67.28  0  301 LEU A O   1 
ATOM   2384 C  CB  . LEU A 1 302 ? 145.659 162.583 161.355 1.00 67.28  0  301 LEU A CB  1 
ATOM   2385 C  CG  . LEU A 1 302 ? 146.834 161.656 161.038 1.00 67.28  0  301 LEU A CG  1 
ATOM   2386 C  CD1 . LEU A 1 302 ? 147.172 161.705 159.557 1.00 67.28  0  301 LEU A CD1 1 
ATOM   2387 C  CD2 . LEU A 1 302 ? 148.046 162.014 161.881 1.00 67.28  0  301 LEU A CD2 1 
ATOM   2388 N  N   . ASN A 1 303 ? 143.661 159.895 160.573 1.00 67.28  0  302 ASN A N   1 
ATOM   2389 C  CA  . ASN A 1 303 ? 143.298 158.578 161.071 1.00 67.28  0  302 ASN A CA  1 
ATOM   2390 C  C   . ASN A 1 303 ? 144.529 157.677 161.046 1.00 67.28  0  302 ASN A C   1 
ATOM   2391 O  O   . ASN A 1 303 ? 145.608 158.071 160.592 1.00 67.28  0  302 ASN A O   1 
ATOM   2392 C  CB  . ASN A 1 303 ? 142.149 157.984 160.254 1.00 67.28  0  302 ASN A CB  1 
ATOM   2393 C  CG  . ASN A 1 303 ? 142.375 158.096 158.763 1.00 67.28  0  302 ASN A CG  1 
ATOM   2394 O  OD1 . ASN A 1 303 ? 143.332 158.724 158.315 1.00 67.28  0  302 ASN A OD1 1 
ATOM   2395 N  ND2 . ASN A 1 303 ? 141.491 157.486 157.983 1.00 67.28  0  302 ASN A ND2 1 
ATOM   2396 N  N   . THR A 1 304 ? 144.359 156.451 161.545 1.00 67.28  0  303 THR A N   1 
ATOM   2397 C  CA  . THR A 1 304 ? 145.493 155.538 161.649 1.00 67.28  0  303 THR A CA  1 
ATOM   2398 C  C   . THR A 1 304 ? 146.034 155.156 160.274 1.00 67.28  0  303 THR A C   1 
ATOM   2399 O  O   . THR A 1 304 ? 147.250 155.015 160.100 1.00 67.28  0  303 THR A O   1 
ATOM   2400 C  CB  . THR A 1 304 ? 145.102 154.296 162.458 1.00 67.28  0  303 THR A CB  1 
ATOM   2401 O  OG1 . THR A 1 304 ? 146.261 153.483 162.683 1.00 67.28  0  303 THR A OG1 1 
ATOM   2402 C  CG2 . THR A 1 304 ? 144.027 153.478 161.751 1.00 67.28  0  303 THR A CG2 1 
ATOM   2403 N  N   . VAL A 1 305 ? 145.152 155.007 159.282 1.00 67.28  0  304 VAL A N   1 
ATOM   2404 C  CA  . VAL A 1 305 ? 145.591 154.630 157.940 1.00 67.28  0  304 VAL A CA  1 
ATOM   2405 C  C   . VAL A 1 305 ? 146.503 155.702 157.357 1.00 67.28  0  304 VAL A C   1 
ATOM   2406 O  O   . VAL A 1 305 ? 147.607 155.414 156.877 1.00 67.28  0  304 VAL A O   1 
ATOM   2407 C  CB  . VAL A 1 305 ? 144.372 154.371 157.036 1.00 67.28  0  304 VAL A CB  1 
ATOM   2408 C  CG1 . VAL A 1 305 ? 144.810 154.125 155.605 1.00 67.28  0  304 VAL A CG1 1 
ATOM   2409 C  CG2 . VAL A 1 305 ? 143.565 153.195 157.562 1.00 67.28  0  304 VAL A CG2 1 
ATOM   2410 N  N   . GLU A 1 306 ? 146.060 156.961 157.407 1.00 67.28  0  305 GLU A N   1 
ATOM   2411 C  CA  . GLU A 1 306 ? 146.869 158.050 156.874 1.00 67.28  0  305 GLU A CA  1 
ATOM   2412 C  C   . GLU A 1 306 ? 148.139 158.244 157.691 1.00 67.28  0  305 GLU A C   1 
ATOM   2413 O  O   . GLU A 1 306 ? 149.198 158.557 157.135 1.00 67.28  0  305 GLU A O   1 
ATOM   2414 C  CB  . GLU A 1 306 ? 146.054 159.342 156.832 1.00 67.28  0  305 GLU A CB  1 
ATOM   2415 C  CG  . GLU A 1 306 ? 146.714 160.467 156.056 1.00 67.28  0  305 GLU A CG  1 
ATOM   2416 C  CD  . GLU A 1 306 ? 146.838 160.157 154.578 1.00 67.28  0  305 GLU A CD  1 
ATOM   2417 O  OE1 . GLU A 1 306 ? 145.798 159.909 153.933 1.00 67.28  0  305 GLU A OE1 1 
ATOM   2418 O  OE2 . GLU A 1 306 ? 147.975 160.159 154.061 1.00 67.28  -1 305 GLU A OE2 1 
ATOM   2419 N  N   . MET A 1 307 ? 148.053 158.067 159.012 1.00 67.28  0  306 MET A N   1 
ATOM   2420 C  CA  . MET A 1 307 ? 149.238 158.204 159.852 1.00 67.28  0  306 MET A CA  1 
ATOM   2421 C  C   . MET A 1 307 ? 150.300 157.183 159.468 1.00 67.28  0  306 MET A C   1 
ATOM   2422 O  O   . MET A 1 307 ? 151.477 157.525 159.313 1.00 67.28  0  306 MET A O   1 
ATOM   2423 C  CB  . MET A 1 307 ? 148.859 158.058 161.326 1.00 67.28  0  306 MET A CB  1 
ATOM   2424 C  CG  . MET A 1 307 ? 150.033 157.734 162.234 1.00 67.28  0  306 MET A CG  1 
ATOM   2425 S  SD  . MET A 1 307 ? 149.557 157.523 163.958 1.00 67.28  0  306 MET A SD  1 
ATOM   2426 C  CE  . MET A 1 307 ? 149.349 155.746 164.034 1.00 67.28  0  306 MET A CE  1 
ATOM   2427 N  N   . LEU A 1 308 ? 149.898 155.921 159.294 1.00 67.28  0  307 LEU A N   1 
ATOM   2428 C  CA  . LEU A 1 308 ? 150.849 154.893 158.881 1.00 67.28  0  307 LEU A CA  1 
ATOM   2429 C  C   . LEU A 1 308 ? 151.390 155.170 157.485 1.00 67.28  0  307 LEU A C   1 
ATOM   2430 O  O   . LEU A 1 308 ? 152.593 155.012 157.236 1.00 67.28  0  307 LEU A O   1 
ATOM   2431 C  CB  . LEU A 1 308 ? 150.190 153.517 158.934 1.00 67.28  0  307 LEU A CB  1 
ATOM   2432 C  CG  . LEU A 1 308 ? 149.701 153.051 160.304 1.00 67.28  0  307 LEU A CG  1 
ATOM   2433 C  CD1 . LEU A 1 308 ? 148.725 151.903 160.144 1.00 67.28  0  307 LEU A CD1 1 
ATOM   2434 C  CD2 . LEU A 1 308 ? 150.870 152.647 161.184 1.00 67.28  0  307 LEU A CD2 1 
ATOM   2435 N  N   . ARG A 1 309 ? 150.521 155.595 156.564 1.00 67.28  0  308 ARG A N   1 
ATOM   2436 C  CA  . ARG A 1 309 ? 150.960 155.875 155.202 1.00 67.28  0  308 ARG A CA  1 
ATOM   2437 C  C   . ARG A 1 309 ? 152.023 156.965 155.183 1.00 67.28  0  308 ARG A C   1 
ATOM   2438 O  O   . ARG A 1 309 ? 153.050 156.838 154.505 1.00 67.28  0  308 ARG A O   1 
ATOM   2439 C  CB  . ARG A 1 309 ? 149.762 156.280 154.344 1.00 67.28  0  308 ARG A CB  1 
ATOM   2440 C  CG  . ARG A 1 309 ? 149.086 155.130 153.625 1.00 67.28  0  308 ARG A CG  1 
ATOM   2441 C  CD  . ARG A 1 309 ? 148.337 155.623 152.401 1.00 67.28  0  308 ARG A CD  1 
ATOM   2442 N  NE  . ARG A 1 309 ? 147.177 156.429 152.765 1.00 67.28  0  308 ARG A NE  1 
ATOM   2443 C  CZ  . ARG A 1 309 ? 145.918 156.039 152.621 1.00 67.28  0  308 ARG A CZ  1 
ATOM   2444 N  NH1 . ARG A 1 309 ? 145.615 154.851 152.123 1.00 67.28  1  308 ARG A NH1 1 
ATOM   2445 N  NH2 . ARG A 1 309 ? 144.939 156.860 152.988 1.00 67.28  0  308 ARG A NH2 1 
ATOM   2446 N  N   . VAL A 1 310 ? 151.795 158.047 155.930 1.00 67.28  0  309 VAL A N   1 
ATOM   2447 C  CA  . VAL A 1 310 ? 152.751 159.148 155.945 1.00 67.28  0  309 VAL A CA  1 
ATOM   2448 C  C   . VAL A 1 310 ? 154.021 158.754 156.690 1.00 67.28  0  309 VAL A C   1 
ATOM   2449 O  O   . VAL A 1 310 ? 155.131 159.091 156.263 1.00 67.28  0  309 VAL A O   1 
ATOM   2450 C  CB  . VAL A 1 310 ? 152.104 160.409 156.539 1.00 67.28  0  309 VAL A CB  1 
ATOM   2451 C  CG1 . VAL A 1 310 ? 153.130 161.523 156.655 1.00 67.28  0  309 VAL A CG1 1 
ATOM   2452 C  CG2 . VAL A 1 310 ? 150.942 160.845 155.667 1.00 67.28  0  309 VAL A CG2 1 
ATOM   2453 N  N   . ALA A 1 311 ? 153.886 158.031 157.806 1.00 67.28  0  310 ALA A N   1 
ATOM   2454 C  CA  . ALA A 1 311 ? 155.065 157.586 158.539 1.00 67.28  0  310 ALA A CA  1 
ATOM   2455 C  C   . ALA A 1 311 ? 155.936 156.672 157.691 1.00 67.28  0  310 ALA A C   1 
ATOM   2456 O  O   . ALA A 1 311 ? 157.156 156.623 157.883 1.00 67.28  0  310 ALA A O   1 
ATOM   2457 C  CB  . ALA A 1 311 ? 154.648 156.879 159.828 1.00 67.28  0  310 ALA A CB  1 
ATOM   2458 N  N   . SER A 1 312 ? 155.333 155.943 156.752 1.00 67.28  0  311 SER A N   1 
ATOM   2459 C  CA  . SER A 1 312 ? 156.125 155.114 155.851 1.00 67.28  0  311 SER A CA  1 
ATOM   2460 C  C   . SER A 1 312 ? 156.734 155.935 154.719 1.00 67.28  0  311 SER A C   1 
ATOM   2461 O  O   . SER A 1 312 ? 157.934 155.829 154.444 1.00 67.28  0  311 SER A O   1 
ATOM   2462 C  CB  . SER A 1 312 ? 155.268 153.986 155.282 1.00 67.28  0  311 SER A CB  1 
ATOM   2463 O  OG  . SER A 1 312 ? 155.985 153.277 154.290 1.00 67.28  0  311 SER A OG  1 
ATOM   2464 N  N   . SER A 1 313 ? 155.922 156.757 154.051 1.00 67.28  0  312 SER A N   1 
ATOM   2465 C  CA  . SER A 1 313 ? 156.388 157.435 152.844 1.00 67.28  0  312 SER A CA  1 
ATOM   2466 C  C   . SER A 1 313 ? 157.389 158.540 153.163 1.00 67.28  0  312 SER A C   1 
ATOM   2467 O  O   . SER A 1 313 ? 158.423 158.655 152.495 1.00 67.28  0  312 SER A O   1 
ATOM   2468 C  CB  . SER A 1 313 ? 155.197 157.999 152.070 1.00 67.28  0  312 SER A CB  1 
ATOM   2469 O  OG  . SER A 1 313 ? 154.579 159.056 152.784 1.00 67.28  0  312 SER A OG  1 
ATOM   2470 N  N   . SER A 1 314 ? 157.105 159.361 154.174 1.00 67.28  0  313 SER A N   1 
ATOM   2471 C  CA  . SER A 1 314 ? 157.917 160.537 154.470 1.00 67.28  0  313 SER A CA  1 
ATOM   2472 C  C   . SER A 1 314 ? 158.897 160.293 155.613 1.00 67.28  0  313 SER A C   1 
ATOM   2473 O  O   . SER A 1 314 ? 160.103 160.502 155.457 1.00 67.28  0  313 SER A O   1 
ATOM   2474 C  CB  . SER A 1 314 ? 157.007 161.729 154.794 1.00 67.28  0  313 SER A CB  1 
ATOM   2475 O  OG  . SER A 1 314 ? 156.580 161.693 156.144 1.00 67.28  0  313 SER A OG  1 
ATOM   2476 N  N   . LEU A 1 315 ? 158.398 159.851 156.767 1.00 67.28  0  314 LEU A N   1 
ATOM   2477 C  CA  . LEU A 1 315 ? 159.238 159.714 157.949 1.00 67.28  0  314 LEU A CA  1 
ATOM   2478 C  C   . LEU A 1 315 ? 160.117 158.471 157.920 1.00 67.28  0  314 LEU A C   1 
ATOM   2479 O  O   . LEU A 1 315 ? 160.999 158.340 158.775 1.00 67.28  0  314 LEU A O   1 
ATOM   2480 C  CB  . LEU A 1 315 ? 158.369 159.700 159.208 1.00 67.28  0  314 LEU A CB  1 
ATOM   2481 C  CG  . LEU A 1 315 ? 157.675 161.024 159.531 1.00 67.28  0  314 LEU A CG  1 
ATOM   2482 C  CD1 . LEU A 1 315 ? 156.461 160.799 160.418 1.00 67.28  0  314 LEU A CD1 1 
ATOM   2483 C  CD2 . LEU A 1 315 ? 158.643 162.006 160.170 1.00 67.28  0  314 LEU A CD2 1 
ATOM   2484 N  N   . GLY A 1 316 ? 159.904 157.565 156.969 1.00 67.28  0  315 GLY A N   1 
ATOM   2485 C  CA  . GLY A 1 316 ? 160.724 156.374 156.856 1.00 67.28  0  315 GLY A CA  1 
ATOM   2486 C  C   . GLY A 1 316 ? 160.610 155.437 158.039 1.00 67.28  0  315 GLY A C   1 
ATOM   2487 O  O   . GLY A 1 316 ? 161.618 154.926 158.535 1.00 67.28  0  315 GLY A O   1 
ATOM   2488 N  N   . MET A 1 317 ? 159.386 155.206 158.503 1.00 67.28  0  316 MET A N   1 
ATOM   2489 C  CA  . MET A 1 317 ? 159.119 154.321 159.627 1.00 67.28  0  316 MET A CA  1 
ATOM   2490 C  C   . MET A 1 317 ? 158.116 153.258 159.208 1.00 67.28  0  316 MET A C   1 
ATOM   2491 O  O   . MET A 1 317 ? 157.145 153.551 158.504 1.00 67.28  0  316 MET A O   1 
ATOM   2492 C  CB  . MET A 1 317 ? 158.587 155.105 160.830 1.00 67.28  0  316 MET A CB  1 
ATOM   2493 C  CG  . MET A 1 317 ? 159.524 156.198 161.315 1.00 67.28  0  316 MET A CG  1 
ATOM   2494 S  SD  . MET A 1 317 ? 158.807 157.228 162.609 1.00 67.28  0  316 MET A SD  1 
ATOM   2495 C  CE  . MET A 1 317 ? 157.664 156.079 163.368 1.00 67.28  0  316 MET A CE  1 
ATOM   2496 N  N   . GLY A 1 318 ? 158.351 152.024 159.646 1.00 67.28  0  317 GLY A N   1 
ATOM   2497 C  CA  . GLY A 1 318 ? 157.489 150.919 159.302 1.00 67.28  0  317 GLY A CA  1 
ATOM   2498 C  C   . GLY A 1 318 ? 156.137 151.024 159.976 1.00 67.28  0  317 GLY A C   1 
ATOM   2499 O  O   . GLY A 1 318 ? 155.947 151.807 160.910 1.00 67.28  0  317 GLY A O   1 
ATOM   2500 N  N   . PRO A 1 319 ? 155.162 150.245 159.499 1.00 67.28  0  318 PRO A N   1 
ATOM   2501 C  CA  . PRO A 1 319 ? 153.824 150.306 160.116 1.00 67.28  0  318 PRO A CA  1 
ATOM   2502 C  C   . PRO A 1 319 ? 153.819 149.918 161.585 1.00 67.28  0  318 PRO A C   1 
ATOM   2503 O  O   . PRO A 1 319 ? 153.235 150.632 162.410 1.00 67.28  0  318 PRO A O   1 
ATOM   2504 C  CB  . PRO A 1 319 ? 153.007 149.331 159.256 1.00 67.28  0  318 PRO A CB  1 
ATOM   2505 C  CG  . PRO A 1 319 ? 153.733 149.275 157.952 1.00 67.28  0  318 PRO A CG  1 
ATOM   2506 C  CD  . PRO A 1 319 ? 155.184 149.379 158.310 1.00 67.28  0  318 PRO A CD  1 
ATOM   2507 N  N   . GLN A 1 320 ? 154.459 148.800 161.938 1.00 67.28  0  319 GLN A N   1 
ATOM   2508 C  CA  . GLN A 1 320 ? 154.473 148.364 163.331 1.00 67.28  0  319 GLN A CA  1 
ATOM   2509 C  C   . GLN A 1 320 ? 155.250 149.335 164.211 1.00 67.28  0  319 GLN A C   1 
ATOM   2510 O  O   . GLN A 1 320 ? 154.834 149.627 165.339 1.00 67.28  0  319 GLN A O   1 
ATOM   2511 C  CB  . GLN A 1 320 ? 155.059 146.957 163.434 1.00 67.28  0  319 GLN A CB  1 
ATOM   2512 C  CG  . GLN A 1 320 ? 155.142 146.418 164.854 1.00 67.28  0  319 GLN A CG  1 
ATOM   2513 C  CD  . GLN A 1 320 ? 153.845 145.784 165.320 1.00 67.28  0  319 GLN A CD  1 
ATOM   2514 O  OE1 . GLN A 1 320 ? 152.778 146.043 164.765 1.00 67.28  0  319 GLN A OE1 1 
ATOM   2515 N  NE2 . GLN A 1 320 ? 153.933 144.946 166.346 1.00 67.28  0  319 GLN A NE2 1 
ATOM   2516 N  N   . HIS A 1 321 ? 156.384 149.838 163.719 1.00 67.28  0  320 HIS A N   1 
ATOM   2517 C  CA  . HIS A 1 321 ? 157.160 150.805 164.490 1.00 67.28  0  320 HIS A CA  1 
ATOM   2518 C  C   . HIS A 1 321 ? 156.371 152.088 164.717 1.00 67.28  0  320 HIS A C   1 
ATOM   2519 O  O   . HIS A 1 321 ? 156.374 152.642 165.824 1.00 67.28  0  320 HIS A O   1 
ATOM   2520 C  CB  . HIS A 1 321 ? 158.478 151.101 163.777 1.00 67.28  0  320 HIS A CB  1 
ATOM   2521 C  CG  . HIS A 1 321 ? 159.485 151.802 164.634 1.00 67.28  0  320 HIS A CG  1 
ATOM   2522 N  ND1 . HIS A 1 321 ? 159.652 151.519 165.972 1.00 67.28  0  320 HIS A ND1 1 
ATOM   2523 C  CD2 . HIS A 1 321 ? 160.381 152.774 164.341 1.00 67.28  0  320 HIS A CD2 1 
ATOM   2524 C  CE1 . HIS A 1 321 ? 160.605 152.286 166.467 1.00 67.28  0  320 HIS A CE1 1 
ATOM   2525 N  NE2 . HIS A 1 321 ? 161.064 153.058 165.498 1.00 67.28  0  320 HIS A NE2 1 
ATOM   2526 N  N   . ALA A 1 322 ? 155.689 152.576 163.678 1.00 67.28  0  321 ALA A N   1 
ATOM   2527 C  CA  . ALA A 1 322 ? 154.866 153.770 163.823 1.00 67.28  0  321 ALA A CA  1 
ATOM   2528 C  C   . ALA A 1 322 ? 153.723 153.534 164.799 1.00 67.28  0  321 ALA A C   1 
ATOM   2529 O  O   . ALA A 1 322 ? 153.405 154.407 165.614 1.00 67.28  0  321 ALA A O   1 
ATOM   2530 C  CB  . ALA A 1 322 ? 154.329 154.208 162.461 1.00 67.28  0  321 ALA A CB  1 
ATOM   2531 N  N   . MET A 1 323 ? 153.094 152.359 164.731 1.00 67.28  0  322 MET A N   1 
ATOM   2532 C  CA  . MET A 1 323 ? 152.018 152.038 165.661 1.00 67.28  0  322 MET A CA  1 
ATOM   2533 C  C   . MET A 1 323 ? 152.522 152.005 167.098 1.00 67.28  0  322 MET A C   1 
ATOM   2534 O  O   . MET A 1 323 ? 151.866 152.529 168.004 1.00 67.28  0  322 MET A O   1 
ATOM   2535 C  CB  . MET A 1 323 ? 151.380 150.703 165.280 1.00 67.28  0  322 MET A CB  1 
ATOM   2536 C  CG  . MET A 1 323 ? 149.965 150.469 165.809 1.00 67.28  0  322 MET A CG  1 
ATOM   2537 S  SD  . MET A 1 323 ? 148.748 151.734 165.388 1.00 67.28  0  322 MET A SD  1 
ATOM   2538 C  CE  . MET A 1 323 ? 148.852 152.821 166.809 1.00 67.28  0  322 MET A CE  1 
ATOM   2539 N  N   . GLN A 1 324 ? 153.689 151.399 167.324 1.00 67.28  0  323 GLN A N   1 
ATOM   2540 C  CA  . GLN A 1 324 ? 154.242 151.343 168.674 1.00 67.28  0  323 GLN A CA  1 
ATOM   2541 C  C   . GLN A 1 324 ? 154.600 152.733 169.188 1.00 67.28  0  323 GLN A C   1 
ATOM   2542 O  O   . GLN A 1 324 ? 154.323 153.061 170.349 1.00 67.28  0  323 GLN A O   1 
ATOM   2543 C  CB  . GLN A 1 324 ? 155.463 150.425 168.701 1.00 67.28  0  323 GLN A CB  1 
ATOM   2544 C  CG  . GLN A 1 324 ? 155.119 148.945 168.764 1.00 67.28  0  323 GLN A CG  1 
ATOM   2545 C  CD  . GLN A 1 324 ? 156.336 148.055 168.604 1.00 67.28  0  323 GLN A CD  1 
ATOM   2546 O  OE1 . GLN A 1 324 ? 157.166 148.270 167.720 1.00 67.28  0  323 GLN A OE1 1 
ATOM   2547 N  NE2 . GLN A 1 324 ? 156.449 147.048 169.462 1.00 67.28  0  323 GLN A NE2 1 
ATOM   2548 N  N   . THR A 1 325 ? 155.213 153.566 168.342 1.00 67.28  0  324 THR A N   1 
ATOM   2549 C  CA  . THR A 1 325 ? 155.559 154.920 168.766 1.00 67.28  0  324 THR A CA  1 
ATOM   2550 C  C   . THR A 1 325 ? 154.311 155.741 169.068 1.00 67.28  0  324 THR A C   1 
ATOM   2551 O  O   . THR A 1 325 ? 154.275 156.495 170.049 1.00 67.28  0  324 THR A O   1 
ATOM   2552 C  CB  . THR A 1 325 ? 156.408 155.611 167.701 1.00 67.28  0  324 THR A CB  1 
ATOM   2553 O  OG1 . THR A 1 325 ? 155.783 155.468 166.420 1.00 67.28  0  324 THR A OG1 1 
ATOM   2554 C  CG2 . THR A 1 325 ? 157.799 155.002 167.652 1.00 67.28  0  324 THR A CG2 1 
ATOM   2555 N  N   . ALA A 1 326 ? 153.276 155.611 168.235 1.00 67.28  0  325 ALA A N   1 
ATOM   2556 C  CA  . ALA A 1 326 ? 152.031 156.329 168.479 1.00 67.28  0  325 ALA A CA  1 
ATOM   2557 C  C   . ALA A 1 326 ? 151.357 155.849 169.757 1.00 67.28  0  325 ALA A C   1 
ATOM   2558 O  O   . ALA A 1 326 ? 150.809 156.657 170.517 1.00 67.28  0  325 ALA A O   1 
ATOM   2559 C  CB  . ALA A 1 326 ? 151.096 156.173 167.281 1.00 67.28  0  325 ALA A CB  1 
ATOM   2560 N  N   . GLU A 1 327 ? 151.382 154.539 170.011 1.00 67.28  0  326 GLU A N   1 
ATOM   2561 C  CA  . GLU A 1 327 ? 150.819 154.015 171.250 1.00 67.28  0  326 GLU A CA  1 
ATOM   2562 C  C   . GLU A 1 327 ? 151.578 154.540 172.460 1.00 67.28  0  326 GLU A C   1 
ATOM   2563 O  O   . GLU A 1 327 ? 150.971 154.881 173.480 1.00 67.28  0  326 GLU A O   1 
ATOM   2564 C  CB  . GLU A 1 327 ? 150.828 152.488 171.230 1.00 67.28  0  326 GLU A CB  1 
ATOM   2565 C  CG  . GLU A 1 327 ? 149.969 151.852 172.310 1.00 67.28  0  326 GLU A CG  1 
ATOM   2566 C  CD  . GLU A 1 327 ? 149.854 150.349 172.156 1.00 67.28  0  326 GLU A CD  1 
ATOM   2567 O  OE1 . GLU A 1 327 ? 150.467 149.798 171.218 1.00 67.28  0  326 GLU A OE1 1 
ATOM   2568 O  OE2 . GLU A 1 327 ? 149.152 149.718 172.973 1.00 67.28  -1 326 GLU A OE2 1 
ATOM   2569 N  N   . ARG A 1 328 ? 152.907 154.614 172.367 1.00 67.28  0  327 ARG A N   1 
ATOM   2570 C  CA  . ARG A 1 328 ? 153.691 155.173 173.464 1.00 67.28  0  327 ARG A CA  1 
ATOM   2571 C  C   . ARG A 1 328 ? 153.356 156.644 173.691 1.00 67.28  0  327 ARG A C   1 
ATOM   2572 O  O   . ARG A 1 328 ? 153.192 157.083 174.838 1.00 67.28  0  327 ARG A O   1 
ATOM   2573 C  CB  . ARG A 1 328 ? 155.182 154.998 173.180 1.00 67.28  0  327 ARG A CB  1 
ATOM   2574 C  CG  . ARG A 1 328 ? 156.088 155.440 174.314 1.00 67.28  0  327 ARG A CG  1 
ATOM   2575 C  CD  . ARG A 1 328 ? 157.125 154.374 174.640 1.00 67.28  0  327 ARG A CD  1 
ATOM   2576 N  NE  . ARG A 1 328 ? 157.684 153.752 173.445 1.00 67.28  0  327 ARG A NE  1 
ATOM   2577 C  CZ  . ARG A 1 328 ? 158.527 154.344 172.610 1.00 67.28  0  327 ARG A CZ  1 
ATOM   2578 N  NH1 . ARG A 1 328 ? 158.953 155.580 172.816 1.00 67.28  1  327 ARG A NH1 1 
ATOM   2579 N  NH2 . ARG A 1 328 ? 158.960 153.677 171.544 1.00 67.28  0  327 ARG A NH2 1 
ATOM   2580 N  N   . LEU A 1 329 ? 153.242 157.416 172.607 1.00 67.28  0  328 LEU A N   1 
ATOM   2581 C  CA  . LEU A 1 329 ? 152.897 158.830 172.728 1.00 67.28  0  328 LEU A CA  1 
ATOM   2582 C  C   . LEU A 1 329 ? 151.524 159.006 173.364 1.00 67.28  0  328 LEU A C   1 
ATOM   2583 O  O   . LEU A 1 329 ? 151.324 159.902 174.192 1.00 67.28  0  328 LEU A O   1 
ATOM   2584 C  CB  . LEU A 1 329 ? 152.941 159.497 171.355 1.00 67.28  0  328 LEU A CB  1 
ATOM   2585 C  CG  . LEU A 1 329 ? 154.300 160.009 170.879 1.00 67.28  0  328 LEU A CG  1 
ATOM   2586 C  CD1 . LEU A 1 329 ? 154.287 160.235 169.379 1.00 67.28  0  328 LEU A CD1 1 
ATOM   2587 C  CD2 . LEU A 1 329 ? 154.673 161.285 171.606 1.00 67.28  0  328 LEU A CD2 1 
ATOM   2588 N  N   . TYR A 1 330 ? 150.564 158.164 172.978 1.00 67.28  0  329 TYR A N   1 
ATOM   2589 C  CA  . TYR A 1 330 ? 149.263 158.158 173.637 1.00 67.28  0  329 TYR A CA  1 
ATOM   2590 C  C   . TYR A 1 330 ? 149.397 157.806 175.111 1.00 67.28  0  329 TYR A C   1 
ATOM   2591 O  O   . TYR A 1 330 ? 148.709 158.380 175.963 1.00 67.28  0  329 TYR A O   1 
ATOM   2592 C  CB  . TYR A 1 330 ? 148.336 157.171 172.928 1.00 67.28  0  329 TYR A CB  1 
ATOM   2593 C  CG  . TYR A 1 330 ? 147.201 156.659 173.779 1.00 67.28  0  329 TYR A CG  1 
ATOM   2594 C  CD1 . TYR A 1 330 ? 146.193 157.506 174.215 1.00 67.28  0  329 TYR A CD1 1 
ATOM   2595 C  CD2 . TYR A 1 330 ? 147.142 155.325 174.152 1.00 67.28  0  329 TYR A CD2 1 
ATOM   2596 C  CE1 . TYR A 1 330 ? 145.156 157.035 174.994 1.00 67.28  0  329 TYR A CE1 1 
ATOM   2597 C  CE2 . TYR A 1 330 ? 146.112 154.847 174.930 1.00 67.28  0  329 TYR A CE2 1 
ATOM   2598 C  CZ  . TYR A 1 330 ? 145.122 155.704 175.348 1.00 67.28  0  329 TYR A CZ  1 
ATOM   2599 O  OH  . TYR A 1 330 ? 144.095 155.224 176.124 1.00 67.28  0  329 TYR A OH  1 
ATOM   2600 N  N   . THR A 1 331 ? 150.280 156.857 175.427 1.00 67.28  0  330 THR A N   1 
ATOM   2601 C  CA  . THR A 1 331 ? 150.449 156.411 176.804 1.00 67.28  0  330 THR A CA  1 
ATOM   2602 C  C   . THR A 1 331 ? 150.960 157.536 177.695 1.00 67.28  0  330 THR A C   1 
ATOM   2603 O  O   . THR A 1 331 ? 150.458 157.737 178.807 1.00 67.28  0  330 THR A O   1 
ATOM   2604 C  CB  . THR A 1 331 ? 151.397 155.214 176.844 1.00 67.28  0  330 THR A CB  1 
ATOM   2605 O  OG1 . THR A 1 331 ? 150.857 154.150 176.051 1.00 67.28  0  330 THR A OG1 1 
ATOM   2606 C  CG2 . THR A 1 331 ? 151.578 154.733 178.261 1.00 67.28  0  330 THR A CG2 1 
ATOM   2607 N  N   . GLN A 1 332 ? 151.963 158.284 177.227 1.00 67.28  0  331 GLN A N   1 
ATOM   2608 C  CA  . GLN A 1 332 ? 152.420 159.426 178.013 1.00 67.28  0  331 GLN A CA  1 
ATOM   2609 C  C   . GLN A 1 332 ? 151.380 160.536 178.083 1.00 67.28  0  331 GLN A C   1 
ATOM   2610 O  O   . GLN A 1 332 ? 151.413 161.340 179.020 1.00 67.28  0  331 GLN A O   1 
ATOM   2611 C  CB  . GLN A 1 332 ? 153.736 159.994 177.471 1.00 67.28  0  331 GLN A CB  1 
ATOM   2612 C  CG  . GLN A 1 332 ? 154.975 159.189 177.841 1.00 67.28  0  331 GLN A CG  1 
ATOM   2613 C  CD  . GLN A 1 332 ? 155.494 158.334 176.707 1.00 67.28  0  331 GLN A CD  1 
ATOM   2614 O  OE1 . GLN A 1 332 ? 155.255 158.625 175.537 1.00 67.28  0  331 GLN A OE1 1 
ATOM   2615 N  NE2 . GLN A 1 332 ? 156.211 157.271 177.050 1.00 67.28  0  331 GLN A NE2 1 
ATOM   2616 N  N   . GLY A 1 333 ? 150.465 160.600 177.125 1.00 67.28  0  332 GLY A N   1 
ATOM   2617 C  CA  . GLY A 1 333 ? 149.426 161.601 177.120 1.00 67.28  0  332 GLY A CA  1 
ATOM   2618 C  C   . GLY A 1 333 ? 149.628 162.743 176.153 1.00 67.28  0  332 GLY A C   1 
ATOM   2619 O  O   . GLY A 1 333 ? 149.111 163.838 176.401 1.00 67.28  0  332 GLY A O   1 
ATOM   2620 N  N   . TYR A 1 334 ? 150.358 162.527 175.061 1.00 67.28  0  333 TYR A N   1 
ATOM   2621 C  CA  . TYR A 1 334 ? 150.634 163.579 174.092 1.00 67.28  0  333 TYR A CA  1 
ATOM   2622 C  C   . TYR A 1 334 ? 149.642 163.606 172.939 1.00 67.28  0  333 TYR A C   1 
ATOM   2623 O  O   . TYR A 1 334 ? 149.344 164.686 172.420 1.00 67.28  0  333 TYR A O   1 
ATOM   2624 C  CB  . TYR A 1 334 ? 152.051 163.420 173.532 1.00 67.28  0  333 TYR A CB  1 
ATOM   2625 C  CG  . TYR A 1 334 ? 153.142 163.733 174.531 1.00 67.28  0  333 TYR A CG  1 
ATOM   2626 C  CD1 . TYR A 1 334 ? 153.137 164.922 175.244 1.00 67.28  0  333 TYR A CD1 1 
ATOM   2627 C  CD2 . TYR A 1 334 ? 154.173 162.835 174.765 1.00 67.28  0  333 TYR A CD2 1 
ATOM   2628 C  CE1 . TYR A 1 334 ? 154.131 165.210 176.159 1.00 67.28  0  333 TYR A CE1 1 
ATOM   2629 C  CE2 . TYR A 1 334 ? 155.170 163.114 175.677 1.00 67.28  0  333 TYR A CE2 1 
ATOM   2630 C  CZ  . TYR A 1 334 ? 155.145 164.303 176.371 1.00 67.28  0  333 TYR A CZ  1 
ATOM   2631 O  OH  . TYR A 1 334 ? 156.137 164.584 177.281 1.00 67.28  0  333 TYR A OH  1 
ATOM   2632 N  N   . ILE A 1 335 ? 149.125 162.448 172.528 1.00 67.28  0  334 ILE A N   1 
ATOM   2633 C  CA  . ILE A 1 335 ? 148.165 162.348 171.439 1.00 67.28  0  334 ILE A CA  1 
ATOM   2634 C  C   . ILE A 1 335 ? 147.002 161.474 171.893 1.00 67.28  0  334 ILE A C   1 
ATOM   2635 O  O   . ILE A 1 335 ? 147.068 160.794 172.917 1.00 67.28  0  334 ILE A O   1 
ATOM   2636 C  CB  . ILE A 1 335 ? 148.793 161.780 170.148 1.00 67.28  0  334 ILE A CB  1 
ATOM   2637 C  CG1 . ILE A 1 335 ? 149.150 160.305 170.332 1.00 67.28  0  334 ILE A CG1 1 
ATOM   2638 C  CG2 . ILE A 1 335 ? 150.016 162.587 169.737 1.00 67.28  0  334 ILE A CG2 1 
ATOM   2639 C  CD1 . ILE A 1 335 ? 149.536 159.608 169.051 1.00 67.28  0  334 ILE A CD1 1 
ATOM   2640 N  N   . SER A 1 336 ? 145.927 161.504 171.111 1.00 67.28  0  335 SER A N   1 
ATOM   2641 C  CA  . SER A 1 336 ? 144.753 160.689 171.388 1.00 67.28  0  335 SER A CA  1 
ATOM   2642 C  C   . SER A 1 336 ? 145.040 159.241 170.993 1.00 67.28  0  335 SER A C   1 
ATOM   2643 O  O   . SER A 1 336 ? 146.165 158.880 170.636 1.00 67.28  0  335 SER A O   1 
ATOM   2644 C  CB  . SER A 1 336 ? 143.533 161.252 170.664 1.00 67.28  0  335 SER A CB  1 
ATOM   2645 O  OG  . SER A 1 336 ? 143.526 160.866 169.301 1.00 67.28  0  335 SER A OG  1 
ATOM   2646 N  N   . TYR A 1 337 ? 144.025 158.391 171.053 1.00 67.28  0  336 TYR A N   1 
ATOM   2647 C  CA  . TYR A 1 337 ? 144.213 156.981 170.730 1.00 67.28  0  336 TYR A CA  1 
ATOM   2648 C  C   . TYR A 1 337 ? 144.453 156.818 169.236 1.00 67.28  0  336 TYR A C   1 
ATOM   2649 O  O   . TYR A 1 337 ? 143.588 157.195 168.434 1.00 67.28  0  336 TYR A O   1 
ATOM   2650 C  CB  . TYR A 1 337 ? 142.997 156.172 171.168 1.00 67.28  0  336 TYR A CB  1 
ATOM   2651 C  CG  . TYR A 1 337 ? 143.273 154.697 171.342 1.00 67.28  0  336 TYR A CG  1 
ATOM   2652 C  CD1 . TYR A 1 337 ? 144.381 154.258 172.052 1.00 67.28  0  336 TYR A CD1 1 
ATOM   2653 C  CD2 . TYR A 1 337 ? 142.422 153.744 170.803 1.00 67.28  0  336 TYR A CD2 1 
ATOM   2654 C  CE1 . TYR A 1 337 ? 144.637 152.911 172.215 1.00 67.28  0  336 TYR A CE1 1 
ATOM   2655 C  CE2 . TYR A 1 337 ? 142.669 152.396 170.963 1.00 67.28  0  336 TYR A CE2 1 
ATOM   2656 C  CZ  . TYR A 1 337 ? 143.778 151.985 171.668 1.00 67.28  0  336 TYR A CZ  1 
ATOM   2657 O  OH  . TYR A 1 337 ? 144.028 150.641 171.827 1.00 67.28  0  336 TYR A OH  1 
ATOM   2658 N  N   . PRO A 1 338 ? 145.599 156.269 168.813 1.00 67.28  0  337 PRO A N   1 
ATOM   2659 C  CA  . PRO A 1 338 ? 145.919 156.149 167.387 1.00 67.28  0  337 PRO A CA  1 
ATOM   2660 C  C   . PRO A 1 338 ? 145.408 154.856 166.752 1.00 67.28  0  337 PRO A C   1 
ATOM   2661 O  O   . PRO A 1 338 ? 146.126 154.173 166.015 1.00 67.28  0  337 PRO A O   1 
ATOM   2662 C  CB  . PRO A 1 338 ? 147.449 156.218 167.379 1.00 67.28  0  337 PRO A CB  1 
ATOM   2663 C  CG  . PRO A 1 338 ? 147.868 155.722 168.743 1.00 67.28  0  337 PRO A CG  1 
ATOM   2664 C  CD  . PRO A 1 338 ? 146.686 155.770 169.670 1.00 67.28  0  337 PRO A CD  1 
ATOM   2665 N  N   . ARG A 1 339 ? 144.150 154.521 167.018 1.00 67.28  0  338 ARG A N   1 
ATOM   2666 C  CA  . ARG A 1 339 ? 143.470 153.382 166.407 1.00 67.28  0  338 ARG A CA  1 
ATOM   2667 C  C   . ARG A 1 339 ? 142.103 153.818 165.909 1.00 67.28  0  338 ARG A C   1 
ATOM   2668 O  O   . ARG A 1 339 ? 141.082 153.164 166.131 1.00 67.28  0  338 ARG A O   1 
ATOM   2669 C  CB  . ARG A 1 339 ? 143.352 152.213 167.381 1.00 67.28  0  338 ARG A CB  1 
ATOM   2670 C  CG  . ARG A 1 339 ? 144.632 151.902 168.140 1.00 67.28  0  338 ARG A CG  1 
ATOM   2671 C  CD  . ARG A 1 339 ? 145.188 150.539 167.768 1.00 67.28  0  338 ARG A CD  1 
ATOM   2672 N  NE  . ARG A 1 339 ? 146.270 150.138 168.658 1.00 67.28  0  338 ARG A NE  1 
ATOM   2673 C  CZ  . ARG A 1 339 ? 147.096 149.128 168.424 1.00 67.28  0  338 ARG A CZ  1 
ATOM   2674 N  NH1 . ARG A 1 339 ? 146.993 148.388 167.332 1.00 67.28  1  338 ARG A NH1 1 
ATOM   2675 N  NH2 . ARG A 1 339 ? 148.049 148.852 169.310 1.00 67.28  0  338 ARG A NH2 1 
ATOM   2676 N  N   . THR A 1 340 ? 142.083 154.951 165.216 1.00 67.28  0  339 THR A N   1 
ATOM   2677 C  CA  . THR A 1 340 ? 140.861 155.638 164.836 1.00 67.28  0  339 THR A CA  1 
ATOM   2678 C  C   . THR A 1 340 ? 140.668 155.582 163.327 1.00 67.28  0  339 THR A C   1 
ATOM   2679 O  O   . THR A 1 340 ? 141.611 155.804 162.562 1.00 67.28  0  339 THR A O   1 
ATOM   2680 C  CB  . THR A 1 340 ? 140.904 157.097 165.298 1.00 67.28  0  339 THR A CB  1 
ATOM   2681 O  OG1 . THR A 1 340 ? 142.033 157.756 164.709 1.00 67.28  0  339 THR A OG1 1 
ATOM   2682 C  CG2 . THR A 1 340 ? 140.999 157.179 166.804 1.00 67.28  0  339 THR A CG2 1 
ATOM   2683 N  N   . GLU A 1 341 ? 139.440 155.278 162.904 1.00 67.28  0  340 GLU A N   1 
ATOM   2684 C  CA  . GLU A 1 341 ? 139.066 155.301 161.496 1.00 67.28  0  340 GLU A CA  1 
ATOM   2685 C  C   . GLU A 1 341 ? 138.120 156.452 161.171 1.00 67.28  0  340 GLU A C   1 
ATOM   2686 O  O   . GLU A 1 341 ? 137.469 156.436 160.122 1.00 67.28  0  340 GLU A O   1 
ATOM   2687 C  CB  . GLU A 1 341 ? 138.439 153.967 161.089 1.00 67.28  0  340 GLU A CB  1 
ATOM   2688 C  CG  . GLU A 1 341 ? 137.283 153.525 161.968 1.00 67.28  0  340 GLU A CG  1 
ATOM   2689 C  CD  . GLU A 1 341 ? 136.686 152.205 161.522 1.00 67.28  0  340 GLU A CD  1 
ATOM   2690 O  OE1 . GLU A 1 341 ? 136.948 151.790 160.373 1.00 67.28  0  340 GLU A OE1 1 
ATOM   2691 O  OE2 . GLU A 1 341 ? 135.956 151.580 162.321 1.00 67.28  -1 340 GLU A OE2 1 
ATOM   2692 N  N   . THR A 1 342 ? 138.031 157.448 162.047 1.00 67.28  0  341 THR A N   1 
ATOM   2693 C  CA  . THR A 1 342 ? 137.158 158.596 161.845 1.00 67.28  0  341 THR A CA  1 
ATOM   2694 C  C   . THR A 1 342 ? 137.983 159.811 161.446 1.00 67.28  0  341 THR A C   1 
ATOM   2695 O  O   . THR A 1 342 ? 139.027 160.090 162.042 1.00 67.28  0  341 THR A O   1 
ATOM   2696 C  CB  . THR A 1 342 ? 136.355 158.914 163.108 1.00 67.28  0  341 THR A CB  1 
ATOM   2697 O  OG1 . THR A 1 342 ? 137.185 159.617 164.040 1.00 67.28  0  341 THR A OG1 1 
ATOM   2698 C  CG2 . THR A 1 342 ? 135.853 157.635 163.756 1.00 67.28  0  341 THR A CG2 1 
ATOM   2699 N  N   . THR A 1 343 ? 137.506 160.534 160.435 1.00 67.28  0  342 THR A N   1 
ATOM   2700 C  CA  . THR A 1 343 ? 138.190 161.712 159.919 1.00 67.28  0  342 THR A CA  1 
ATOM   2701 C  C   . THR A 1 343 ? 137.324 162.962 160.047 1.00 67.28  0  342 THR A C   1 
ATOM   2702 O  O   . THR A 1 343 ? 137.411 163.872 159.222 1.00 67.28  0  342 THR A O   1 
ATOM   2703 C  CB  . THR A 1 343 ? 138.609 161.500 158.465 1.00 67.28  0  342 THR A CB  1 
ATOM   2704 O  OG1 . THR A 1 343 ? 137.484 161.041 157.706 1.00 67.28  0  342 THR A OG1 1 
ATOM   2705 C  CG2 . THR A 1 343 ? 139.718 160.465 158.380 1.00 67.28  0  342 THR A CG2 1 
ATOM   2706 N  N   . HIS A 1 344 ? 136.485 163.017 161.080 1.00 67.28  0  343 HIS A N   1 
ATOM   2707 C  CA  . HIS A 1 344 ? 135.601 164.155 161.307 1.00 67.28  0  343 HIS A CA  1 
ATOM   2708 C  C   . HIS A 1 344 ? 135.602 164.485 162.790 1.00 67.28  0  343 HIS A C   1 
ATOM   2709 O  O   . HIS A 1 344 ? 135.313 163.619 163.620 1.00 67.28  0  343 HIS A O   1 
ATOM   2710 C  CB  . HIS A 1 344 ? 134.179 163.858 160.822 1.00 67.28  0  343 HIS A CB  1 
ATOM   2711 C  CG  . HIS A 1 344 ? 133.179 164.903 161.206 1.00 67.28  0  343 HIS A CG  1 
ATOM   2712 N  ND1 . HIS A 1 344 ? 131.993 164.600 161.841 1.00 67.28  0  343 HIS A ND1 1 
ATOM   2713 C  CD2 . HIS A 1 344 ? 133.186 166.247 161.044 1.00 67.28  0  343 HIS A CD2 1 
ATOM   2714 C  CE1 . HIS A 1 344 ? 131.314 165.713 162.053 1.00 67.28  0  343 HIS A CE1 1 
ATOM   2715 N  NE2 . HIS A 1 344 ? 132.015 166.726 161.580 1.00 67.28  0  343 HIS A NE2 1 
ATOM   2716 N  N   . TYR A 1 345 ? 135.928 165.730 163.117 1.00 67.28  0  344 TYR A N   1 
ATOM   2717 C  CA  . TYR A 1 345 ? 135.969 166.146 164.509 1.00 67.28  0  344 TYR A CA  1 
ATOM   2718 C  C   . TYR A 1 345 ? 134.557 166.239 165.083 1.00 67.28  0  344 TYR A C   1 
ATOM   2719 O  O   . TYR A 1 345 ? 133.654 166.774 164.431 1.00 67.28  0  344 TYR A O   1 
ATOM   2720 C  CB  . TYR A 1 345 ? 136.671 167.494 164.642 1.00 67.28  0  344 TYR A CB  1 
ATOM   2721 C  CG  . TYR A 1 345 ? 138.155 167.430 164.384 1.00 67.28  0  344 TYR A CG  1 
ATOM   2722 C  CD1 . TYR A 1 345 ? 139.029 167.013 165.373 1.00 67.28  0  344 TYR A CD1 1 
ATOM   2723 C  CD2 . TYR A 1 345 ? 138.681 167.771 163.148 1.00 67.28  0  344 TYR A CD2 1 
ATOM   2724 C  CE1 . TYR A 1 345 ? 140.382 166.950 165.144 1.00 67.28  0  344 TYR A CE1 1 
ATOM   2725 C  CE2 . TYR A 1 345 ? 140.037 167.711 162.908 1.00 67.28  0  344 TYR A CE2 1 
ATOM   2726 C  CZ  . TYR A 1 345 ? 140.884 167.298 163.911 1.00 67.28  0  344 TYR A CZ  1 
ATOM   2727 O  OH  . TYR A 1 345 ? 142.239 167.234 163.679 1.00 67.28  0  344 TYR A OH  1 
ATOM   2728 N  N   . PRO A 1 346 ? 134.335 165.726 166.289 1.00 67.28  0  345 PRO A N   1 
ATOM   2729 C  CA  . PRO A 1 346 ? 133.039 165.917 166.945 1.00 67.28  0  345 PRO A CA  1 
ATOM   2730 C  C   . PRO A 1 346 ? 132.798 167.382 167.270 1.00 67.28  0  345 PRO A C   1 
ATOM   2731 O  O   . PRO A 1 346 ? 133.726 168.180 167.419 1.00 67.28  0  345 PRO A O   1 
ATOM   2732 C  CB  . PRO A 1 346 ? 133.155 165.077 168.223 1.00 67.28  0  345 PRO A CB  1 
ATOM   2733 C  CG  . PRO A 1 346 ? 134.258 164.106 167.947 1.00 67.28  0  345 PRO A CG  1 
ATOM   2734 C  CD  . PRO A 1 346 ? 135.216 164.829 167.053 1.00 67.28  0  345 PRO A CD  1 
ATOM   2735 N  N   . GLU A 1 347 ? 131.513 167.733 167.369 1.00 71.37  0  346 GLU A N   1 
ATOM   2736 C  CA  . GLU A 1 347 ? 131.144 169.117 167.648 1.00 71.37  0  346 GLU A CA  1 
ATOM   2737 C  C   . GLU A 1 347 ? 131.656 169.566 169.012 1.00 71.37  0  346 GLU A C   1 
ATOM   2738 O  O   . GLU A 1 347 ? 132.139 170.695 169.160 1.00 71.37  0  346 GLU A O   1 
ATOM   2739 C  CB  . GLU A 1 347 ? 129.627 169.280 167.564 1.00 71.37  0  346 GLU A CB  1 
ATOM   2740 C  CG  . GLU A 1 347 ? 129.093 169.378 166.144 1.00 71.37  0  346 GLU A CG  1 
ATOM   2741 C  CD  . GLU A 1 347 ? 127.590 169.189 166.072 1.00 71.37  0  346 GLU A CD  1 
ATOM   2742 O  OE1 . GLU A 1 347 ? 126.919 169.354 167.112 1.00 71.37  0  346 GLU A OE1 1 
ATOM   2743 O  OE2 . GLU A 1 347 ? 127.081 168.876 164.976 1.00 71.37  -1 346 GLU A OE2 1 
ATOM   2744 N  N   . ASN A 1 348 ? 131.562 168.699 170.017 1.00 71.65  0  347 ASN A N   1 
ATOM   2745 C  CA  . ASN A 1 348 ? 131.993 169.035 171.375 1.00 71.65  0  347 ASN A CA  1 
ATOM   2746 C  C   . ASN A 1 348 ? 133.470 168.688 171.577 1.00 71.65  0  347 ASN A C   1 
ATOM   2747 O  O   . ASN A 1 348 ? 133.848 167.887 172.432 1.00 71.65  0  347 ASN A O   1 
ATOM   2748 C  CB  . ASN A 1 348 ? 131.108 168.329 172.396 1.00 71.65  0  347 ASN A CB  1 
ATOM   2749 C  CG  . ASN A 1 348 ? 131.035 166.831 172.169 1.00 71.65  0  347 ASN A CG  1 
ATOM   2750 O  OD1 . ASN A 1 348 ? 130.266 166.355 171.334 1.00 71.65  0  347 ASN A OD1 1 
ATOM   2751 N  ND2 . ASN A 1 348 ? 131.837 166.080 172.914 1.00 71.65  0  347 ASN A ND2 1 
ATOM   2752 N  N   . PHE A 1 349 ? 134.315 169.321 170.766 1.00 67.28  0  348 PHE A N   1 
ATOM   2753 C  CA  . PHE A 1 349 ? 135.758 169.140 170.833 1.00 67.28  0  348 PHE A CA  1 
ATOM   2754 C  C   . PHE A 1 349 ? 136.431 170.484 171.068 1.00 67.28  0  348 PHE A C   1 
ATOM   2755 O  O   . PHE A 1 349 ? 135.970 171.516 170.569 1.00 67.28  0  348 PHE A O   1 
ATOM   2756 C  CB  . PHE A 1 349 ? 136.296 168.497 169.551 1.00 67.28  0  348 PHE A CB  1 
ATOM   2757 C  CG  . PHE A 1 349 ? 137.525 167.661 169.764 1.00 67.28  0  348 PHE A CG  1 
ATOM   2758 C  CD1 . PHE A 1 349 ? 137.440 166.432 170.395 1.00 67.28  0  348 PHE A CD1 1 
ATOM   2759 C  CD2 . PHE A 1 349 ? 138.763 168.102 169.334 1.00 67.28  0  348 PHE A CD2 1 
ATOM   2760 C  CE1 . PHE A 1 349 ? 138.568 165.660 170.594 1.00 67.28  0  348 PHE A CE1 1 
ATOM   2761 C  CE2 . PHE A 1 349 ? 139.895 167.335 169.529 1.00 67.28  0  348 PHE A CE2 1 
ATOM   2762 C  CZ  . PHE A 1 349 ? 139.797 166.113 170.159 1.00 67.28  0  348 PHE A CZ  1 
ATOM   2763 N  N   . ASP A 1 350 ? 137.524 170.468 171.831 1.00 68.01  0  349 ASP A N   1 
ATOM   2764 C  CA  . ASP A 1 350 ? 138.223 171.697 172.214 1.00 68.01  0  349 ASP A CA  1 
ATOM   2765 C  C   . ASP A 1 350 ? 139.377 171.966 171.247 1.00 68.01  0  349 ASP A C   1 
ATOM   2766 O  O   . ASP A 1 350 ? 140.561 171.877 171.583 1.00 68.01  0  349 ASP A O   1 
ATOM   2767 C  CB  . ASP A 1 350 ? 138.707 171.604 173.656 1.00 68.01  0  349 ASP A CB  1 
ATOM   2768 C  CG  . ASP A 1 350 ? 138.825 172.961 174.319 1.00 68.01  0  349 ASP A CG  1 
ATOM   2769 O  OD1 . ASP A 1 350 ? 138.489 173.973 173.668 1.00 68.01  0  349 ASP A OD1 1 
ATOM   2770 O  OD2 . ASP A 1 350 ? 139.254 173.018 175.490 1.00 68.01  -1 349 ASP A OD2 1 
ATOM   2771 N  N   . LEU A 1 351 ? 138.999 172.312 170.014 1.00 67.28  0  350 LEU A N   1 
ATOM   2772 C  CA  . LEU A 1 351 ? 139.994 172.669 169.008 1.00 67.28  0  350 LEU A CA  1 
ATOM   2773 C  C   . LEU A 1 351 ? 140.770 173.912 169.422 1.00 67.28  0  350 LEU A C   1 
ATOM   2774 O  O   . LEU A 1 351 ? 141.996 173.974 169.261 1.00 67.28  0  350 LEU A O   1 
ATOM   2775 C  CB  . LEU A 1 351 ? 139.316 172.892 167.656 1.00 67.28  0  350 LEU A CB  1 
ATOM   2776 C  CG  . LEU A 1 351 ? 138.676 171.682 166.973 1.00 67.28  0  350 LEU A CG  1 
ATOM   2777 C  CD1 . LEU A 1 351 ? 138.214 172.044 165.571 1.00 67.28  0  350 LEU A CD1 1 
ATOM   2778 C  CD2 . LEU A 1 351 ? 139.642 170.515 166.932 1.00 67.28  0  350 LEU A CD2 1 
ATOM   2779 N  N   . LYS A 1 352 ? 140.071 174.916 169.957 1.00 67.28  0  351 LYS A N   1 
ATOM   2780 C  CA  . LYS A 1 352 ? 140.740 176.140 170.380 1.00 67.28  0  351 LYS A CA  1 
ATOM   2781 C  C   . LYS A 1 352 ? 141.695 175.873 171.537 1.00 67.28  0  351 LYS A C   1 
ATOM   2782 O  O   . LYS A 1 352 ? 142.799 176.427 171.577 1.00 67.28  0  351 LYS A O   1 
ATOM   2783 C  CB  . LYS A 1 352 ? 139.707 177.199 170.761 1.00 67.28  0  351 LYS A CB  1 
ATOM   2784 C  CG  . LYS A 1 352 ? 140.122 178.619 170.409 1.00 67.28  0  351 LYS A CG  1 
ATOM   2785 C  CD  . LYS A 1 352 ? 139.079 179.630 170.855 1.00 67.28  0  351 LYS A CD  1 
ATOM   2786 C  CE  . LYS A 1 352 ? 139.062 179.779 172.367 1.00 67.28  0  351 LYS A CE  1 
ATOM   2787 N  NZ  . LYS A 1 352 ? 140.354 180.312 172.878 1.00 67.28  1  351 LYS A NZ  1 
ATOM   2788 N  N   . GLY A 1 353 ? 141.295 175.021 172.482 1.00 67.28  0  352 GLY A N   1 
ATOM   2789 C  CA  . GLY A 1 353 ? 142.197 174.660 173.564 1.00 67.28  0  352 GLY A CA  1 
ATOM   2790 C  C   . GLY A 1 353 ? 143.415 173.897 173.077 1.00 67.28  0  352 GLY A C   1 
ATOM   2791 O  O   . GLY A 1 353 ? 144.537 174.139 173.535 1.00 67.28  0  352 GLY A O   1 
ATOM   2792 N  N   . SER A 1 354 ? 143.213 172.969 172.137 1.00 67.28  0  353 SER A N   1 
ATOM   2793 C  CA  . SER A 1 354 ? 144.339 172.230 171.577 1.00 67.28  0  353 SER A CA  1 
ATOM   2794 C  C   . SER A 1 354 ? 145.309 173.165 170.866 1.00 67.28  0  353 SER A C   1 
ATOM   2795 O  O   . SER A 1 354 ? 146.530 172.999 170.969 1.00 67.28  0  353 SER A O   1 
ATOM   2796 C  CB  . SER A 1 354 ? 143.836 171.148 170.622 1.00 67.28  0  353 SER A CB  1 
ATOM   2797 O  OG  . SER A 1 354 ? 143.083 170.168 171.315 1.00 67.28  0  353 SER A OG  1 
ATOM   2798 N  N   . LEU A 1 355 ? 144.784 174.150 170.134 1.00 67.28  0  354 LEU A N   1 
ATOM   2799 C  CA  . LEU A 1 355 ? 145.651 175.160 169.533 1.00 67.28  0  354 LEU A CA  1 
ATOM   2800 C  C   . LEU A 1 355 ? 146.380 175.969 170.598 1.00 67.28  0  354 LEU A C   1 
ATOM   2801 O  O   . LEU A 1 355 ? 147.573 176.262 170.459 1.00 67.28  0  354 LEU A O   1 
ATOM   2802 C  CB  . LEU A 1 355 ? 144.841 176.087 168.629 1.00 67.28  0  354 LEU A CB  1 
ATOM   2803 C  CG  . LEU A 1 355 ? 144.230 175.456 167.382 1.00 67.28  0  354 LEU A CG  1 
ATOM   2804 C  CD1 . LEU A 1 355 ? 143.344 176.454 166.658 1.00 67.28  0  354 LEU A CD1 1 
ATOM   2805 C  CD2 . LEU A 1 355 ? 145.333 174.964 166.477 1.00 67.28  0  354 LEU A CD2 1 
ATOM   2806 N  N   . ARG A 1 356 ? 145.675 176.345 171.668 1.00 67.28  0  355 ARG A N   1 
ATOM   2807 C  CA  . ARG A 1 356 ? 146.282 177.161 172.712 1.00 67.28  0  355 ARG A CA  1 
ATOM   2808 C  C   . ARG A 1 356 ? 147.395 176.416 173.434 1.00 67.28  0  355 ARG A C   1 
ATOM   2809 O  O   . ARG A 1 356 ? 148.319 177.045 173.962 1.00 67.28  0  355 ARG A O   1 
ATOM   2810 C  CB  . ARG A 1 356 ? 145.215 177.613 173.709 1.00 67.28  0  355 ARG A CB  1 
ATOM   2811 C  CG  . ARG A 1 356 ? 145.625 178.793 174.571 1.00 67.28  0  355 ARG A CG  1 
ATOM   2812 C  CD  . ARG A 1 356 ? 144.461 179.306 175.406 1.00 67.28  0  355 ARG A CD  1 
ATOM   2813 N  NE  . ARG A 1 356 ? 143.171 179.033 174.786 1.00 67.28  0  355 ARG A NE  1 
ATOM   2814 C  CZ  . ARG A 1 356 ? 142.271 178.187 175.270 1.00 67.28  0  355 ARG A CZ  1 
ATOM   2815 N  NH1 . ARG A 1 356 ? 142.489 177.512 176.387 1.00 67.28  1  355 ARG A NH1 1 
ATOM   2816 N  NH2 . ARG A 1 356 ? 141.127 178.012 174.616 1.00 67.28  0  355 ARG A NH2 1 
ATOM   2817 N  N   . GLN A 1 357 ? 147.320 175.083 173.480 1.00 67.28  0  356 GLN A N   1 
ATOM   2818 C  CA  . GLN A 1 357 ? 148.396 174.315 174.101 1.00 67.28  0  356 GLN A CA  1 
ATOM   2819 C  C   . GLN A 1 357 ? 149.719 174.530 173.377 1.00 67.28  0  356 GLN A C   1 
ATOM   2820 O  O   . GLN A 1 357 ? 150.762 174.713 174.016 1.00 67.28  0  356 GLN A O   1 
ATOM   2821 C  CB  . GLN A 1 357 ? 148.038 172.829 174.132 1.00 67.28  0  356 GLN A CB  1 
ATOM   2822 C  CG  . GLN A 1 357 ? 146.848 172.490 175.009 1.00 67.28  0  356 GLN A CG  1 
ATOM   2823 C  CD  . GLN A 1 357 ? 147.091 172.822 176.467 1.00 67.28  0  356 GLN A CD  1 
ATOM   2824 O  OE1 . GLN A 1 357 ? 146.505 173.759 177.010 1.00 67.28  0  356 GLN A OE1 1 
ATOM   2825 N  NE2 . GLN A 1 357 ? 147.961 172.053 177.111 1.00 67.28  0  356 GLN A NE2 1 
ATOM   2826 N  N   . GLN A 1 358 ? 149.699 174.512 172.049 1.00 67.28  0  357 GLN A N   1 
ATOM   2827 C  CA  . GLN A 1 358 ? 150.912 174.689 171.250 1.00 67.28  0  357 GLN A CA  1 
ATOM   2828 C  C   . GLN A 1 358 ? 151.035 176.127 170.750 1.00 67.28  0  357 GLN A C   1 
ATOM   2829 O  O   . GLN A 1 358 ? 150.979 176.410 169.554 1.00 67.28  0  357 GLN A O   1 
ATOM   2830 C  CB  . GLN A 1 358 ? 150.930 173.696 170.095 1.00 67.28  0  357 GLN A CB  1 
ATOM   2831 C  CG  . GLN A 1 358 ? 151.070 172.259 170.540 1.00 67.28  0  357 GLN A CG  1 
ATOM   2832 C  CD  . GLN A 1 358 ? 151.012 171.295 169.383 1.00 67.28  0  357 GLN A CD  1 
ATOM   2833 O  OE1 . GLN A 1 358 ? 150.434 171.597 168.340 1.00 67.28  0  357 GLN A OE1 1 
ATOM   2834 N  NE2 . GLN A 1 358 ? 151.612 170.124 169.558 1.00 67.28  0  357 GLN A NE2 1 
ATOM   2835 N  N   . ALA A 1 359 ? 151.213 177.046 171.696 1.00 67.28  0  358 ALA A N   1 
ATOM   2836 C  CA  . ALA A 1 359 ? 151.420 178.453 171.385 1.00 67.28  0  358 ALA A CA  1 
ATOM   2837 C  C   . ALA A 1 359 ? 152.812 178.935 171.771 1.00 67.28  0  358 ALA A C   1 
ATOM   2838 O  O   . ALA A 1 359 ? 153.094 180.133 171.667 1.00 67.28  0  358 ALA A O   1 
ATOM   2839 C  CB  . ALA A 1 359 ? 150.357 179.311 172.075 1.00 67.28  0  358 ALA A CB  1 
ATOM   2840 N  N   . ASN A 1 360 ? 153.689 178.032 172.211 1.00 67.28  0  359 ASN A N   1 
ATOM   2841 C  CA  . ASN A 1 360 ? 155.032 178.395 172.633 1.00 67.28  0  359 ASN A CA  1 
ATOM   2842 C  C   . ASN A 1 360 ? 156.136 177.692 171.858 1.00 67.28  0  359 ASN A C   1 
ATOM   2843 O  O   . ASN A 1 360 ? 157.308 178.037 172.045 1.00 67.28  0  359 ASN A O   1 
ATOM   2844 C  CB  . ASN A 1 360 ? 155.219 178.106 174.131 1.00 67.28  0  359 ASN A CB  1 
ATOM   2845 C  CG  . ASN A 1 360 ? 154.396 179.026 175.011 1.00 67.28  0  359 ASN A CG  1 
ATOM   2846 O  OD1 . ASN A 1 360 ? 153.670 179.889 174.520 1.00 67.28  0  359 ASN A OD1 1 
ATOM   2847 N  ND2 . ASN A 1 360 ? 154.507 178.845 176.322 1.00 67.28  0  359 ASN A ND2 1 
ATOM   2848 N  N   . HIS A 1 361 ? 155.810 176.728 171.007 1.00 67.28  0  360 HIS A N   1 
ATOM   2849 C  CA  . HIS A 1 361 ? 156.842 176.030 170.248 1.00 67.28  0  360 HIS A CA  1 
ATOM   2850 C  C   . HIS A 1 361 ? 157.398 176.946 169.163 1.00 67.28  0  360 HIS A C   1 
ATOM   2851 O  O   . HIS A 1 361 ? 156.623 177.537 168.402 1.00 67.28  0  360 HIS A O   1 
ATOM   2852 C  CB  . HIS A 1 361 ? 156.287 174.752 169.628 1.00 67.28  0  360 HIS A CB  1 
ATOM   2853 C  CG  . HIS A 1 361 ? 157.346 173.796 169.178 1.00 67.28  0  360 HIS A CG  1 
ATOM   2854 N  ND1 . HIS A 1 361 ? 158.179 174.058 168.112 1.00 67.28  0  360 HIS A ND1 1 
ATOM   2855 C  CD2 . HIS A 1 361 ? 157.716 172.585 169.656 1.00 67.28  0  360 HIS A CD2 1 
ATOM   2856 C  CE1 . HIS A 1 361 ? 159.013 173.047 167.949 1.00 67.28  0  360 HIS A CE1 1 
ATOM   2857 N  NE2 . HIS A 1 361 ? 158.754 172.140 168.874 1.00 67.28  0  360 HIS A NE2 1 
ATOM   2858 N  N   . PRO A 1 362 ? 158.722 177.095 169.063 1.00 67.28  0  361 PRO A N   1 
ATOM   2859 C  CA  . PRO A 1 362 ? 159.285 178.034 168.078 1.00 67.28  0  361 PRO A CA  1 
ATOM   2860 C  C   . PRO A 1 362 ? 158.934 177.710 166.636 1.00 67.28  0  361 PRO A C   1 
ATOM   2861 O  O   . PRO A 1 362 ? 158.796 178.634 165.825 1.00 67.28  0  361 PRO A O   1 
ATOM   2862 C  CB  . PRO A 1 362 ? 160.797 177.929 168.324 1.00 67.28  0  361 PRO A CB  1 
ATOM   2863 C  CG  . PRO A 1 362 ? 160.923 177.404 169.719 1.00 67.28  0  361 PRO A CG  1 
ATOM   2864 C  CD  . PRO A 1 362 ? 159.764 176.478 169.899 1.00 67.28  0  361 PRO A CD  1 
ATOM   2865 N  N   . TYR A 1 363 ? 158.796 176.431 166.286 1.00 67.28  0  362 TYR A N   1 
ATOM   2866 C  CA  . TYR A 1 363 ? 158.541 176.046 164.901 1.00 67.28  0  362 TYR A CA  1 
ATOM   2867 C  C   . TYR A 1 363 ? 157.209 176.597 164.404 1.00 67.28  0  362 TYR A C   1 
ATOM   2868 O  O   . TYR A 1 363 ? 157.180 177.439 163.502 1.00 67.28  0  362 TYR A O   1 
ATOM   2869 C  CB  . TYR A 1 363 ? 158.568 174.522 164.748 1.00 67.28  0  362 TYR A CB  1 
ATOM   2870 C  CG  . TYR A 1 363 ? 159.945 173.890 164.835 1.00 67.28  0  362 TYR A CG  1 
ATOM   2871 C  CD1 . TYR A 1 363 ? 161.004 174.546 165.450 1.00 67.28  0  362 TYR A CD1 1 
ATOM   2872 C  CD2 . TYR A 1 363 ? 160.182 172.632 164.298 1.00 67.28  0  362 TYR A CD2 1 
ATOM   2873 C  CE1 . TYR A 1 363 ? 162.257 173.967 165.527 1.00 67.28  0  362 TYR A CE1 1 
ATOM   2874 C  CE2 . TYR A 1 363 ? 161.431 172.047 164.370 1.00 67.28  0  362 TYR A CE2 1 
ATOM   2875 C  CZ  . TYR A 1 363 ? 162.464 172.718 164.986 1.00 67.28  0  362 TYR A CZ  1 
ATOM   2876 O  OH  . TYR A 1 363 ? 163.710 172.139 165.061 1.00 67.28  0  362 TYR A OH  1 
ATOM   2877 N  N   . TRP A 1 364 ? 156.103 176.130 164.984 1.00 67.28  0  363 TRP A N   1 
ATOM   2878 C  CA  . TRP A 1 364 ? 154.773 176.632 164.643 1.00 67.28  0  363 TRP A CA  1 
ATOM   2879 C  C   . TRP A 1 364 ? 154.302 177.550 165.768 1.00 67.28  0  363 TRP A C   1 
ATOM   2880 O  O   . TRP A 1 364 ? 153.557 177.158 166.665 1.00 67.28  0  363 TRP A O   1 
ATOM   2881 C  CB  . TRP A 1 364 ? 153.807 175.476 164.398 1.00 67.28  0  363 TRP A CB  1 
ATOM   2882 C  CG  . TRP A 1 364 ? 153.971 174.334 165.352 1.00 67.28  0  363 TRP A CG  1 
ATOM   2883 C  CD1 . TRP A 1 364 ? 153.406 174.207 166.586 1.00 67.28  0  363 TRP A CD1 1 
ATOM   2884 C  CD2 . TRP A 1 364 ? 154.753 173.152 165.146 1.00 67.28  0  363 TRP A CD2 1 
ATOM   2885 N  NE1 . TRP A 1 364 ? 153.789 173.022 167.163 1.00 67.28  0  363 TRP A NE1 1 
ATOM   2886 C  CE2 . TRP A 1 364 ? 154.616 172.355 166.299 1.00 67.28  0  363 TRP A CE2 1 
ATOM   2887 C  CE3 . TRP A 1 364 ? 155.556 172.692 164.099 1.00 67.28  0  363 TRP A CE3 1 
ATOM   2888 C  CZ2 . TRP A 1 364 ? 155.252 171.125 166.435 1.00 67.28  0  363 TRP A CZ2 1 
ATOM   2889 C  CZ3 . TRP A 1 364 ? 156.187 171.470 164.236 1.00 67.28  0  363 TRP A CZ3 1 
ATOM   2890 C  CH2 . TRP A 1 364 ? 156.031 170.701 165.395 1.00 67.28  0  363 TRP A CH2 1 
ATOM   2891 N  N   . ALA A 1 365 ? 154.749 178.801 165.706 1.00 67.28  0  364 ALA A N   1 
ATOM   2892 C  CA  . ALA A 1 365 ? 154.366 179.813 166.680 1.00 67.28  0  364 ALA A CA  1 
ATOM   2893 C  C   . ALA A 1 365 ? 153.553 180.935 166.059 1.00 67.28  0  364 ALA A C   1 
ATOM   2894 O  O   . ALA A 1 365 ? 152.450 181.232 166.535 1.00 67.28  0  364 ALA A O   1 
ATOM   2895 C  CB  . ALA A 1 365 ? 155.614 180.390 167.366 1.00 67.28  0  364 ALA A CB  1 
ATOM   2896 N  N   . ASP A 1 366 ? 154.072 181.570 165.006 1.00 68.21  0  365 ASP A N   1 
ATOM   2897 C  CA  . ASP A 1 366 ? 153.352 182.664 164.365 1.00 68.21  0  365 ASP A CA  1 
ATOM   2898 C  C   . ASP A 1 366 ? 152.042 182.183 163.756 1.00 68.21  0  365 ASP A C   1 
ATOM   2899 O  O   . ASP A 1 366 ? 151.020 182.874 163.840 1.00 68.21  0  365 ASP A O   1 
ATOM   2900 C  CB  . ASP A 1 366 ? 154.232 183.316 163.299 1.00 68.21  0  365 ASP A CB  1 
ATOM   2901 C  CG  . ASP A 1 366 ? 155.519 183.875 163.869 1.00 68.21  0  365 ASP A CG  1 
ATOM   2902 O  OD1 . ASP A 1 366 ? 155.541 184.211 165.072 1.00 68.21  0  365 ASP A OD1 1 
ATOM   2903 O  OD2 . ASP A 1 366 ? 156.509 183.980 163.115 1.00 68.21  -1 365 ASP A OD2 1 
ATOM   2904 N  N   . THR A 1 367 ? 152.053 181.002 163.134 1.00 67.28  0  366 THR A N   1 
ATOM   2905 C  CA  . THR A 1 367 ? 150.836 180.474 162.524 1.00 67.28  0  366 THR A CA  1 
ATOM   2906 C  C   . THR A 1 367 ? 149.756 180.238 163.572 1.00 67.28  0  366 THR A C   1 
ATOM   2907 O  O   . THR A 1 367 ? 148.597 180.626 163.384 1.00 67.28  0  366 THR A O   1 
ATOM   2908 C  CB  . THR A 1 367 ? 151.144 179.182 161.768 1.00 67.28  0  366 THR A CB  1 
ATOM   2909 O  OG1 . THR A 1 367 ? 152.367 179.333 161.037 1.00 67.28  0  366 THR A OG1 1 
ATOM   2910 C  CG2 . THR A 1 367 ? 150.019 178.852 160.800 1.00 67.28  0  366 THR A CG2 1 
ATOM   2911 N  N   . VAL A 1 368 ? 150.122 179.615 164.693 1.00 67.28  0  367 VAL A N   1 
ATOM   2912 C  CA  . VAL A 1 368 ? 149.144 179.343 165.742 1.00 67.28  0  367 VAL A CA  1 
ATOM   2913 C  C   . VAL A 1 368 ? 148.661 180.641 166.374 1.00 67.28  0  367 VAL A C   1 
ATOM   2914 O  O   . VAL A 1 368 ? 147.471 180.792 166.683 1.00 67.28  0  367 VAL A O   1 
ATOM   2915 C  CB  . VAL A 1 368 ? 149.737 178.386 166.791 1.00 67.28  0  367 VAL A CB  1 
ATOM   2916 C  CG1 . VAL A 1 368 ? 148.682 178.003 167.816 1.00 67.28  0  367 VAL A CG1 1 
ATOM   2917 C  CG2 . VAL A 1 368 ? 150.303 177.148 166.116 1.00 67.28  0  367 VAL A CG2 1 
ATOM   2918 N  N   . LYS A 1 369 ? 149.569 181.600 166.577 1.00 67.28  0  368 LYS A N   1 
ATOM   2919 C  CA  . LYS A 1 369 ? 149.171 182.878 167.157 1.00 67.28  0  368 LYS A CA  1 
ATOM   2920 C  C   . LYS A 1 369 ? 148.191 183.611 166.252 1.00 67.28  0  368 LYS A C   1 
ATOM   2921 O  O   . LYS A 1 369 ? 147.194 184.165 166.727 1.00 67.28  0  368 LYS A O   1 
ATOM   2922 C  CB  . LYS A 1 369 ? 150.405 183.738 167.426 1.00 67.28  0  368 LYS A CB  1 
ATOM   2923 C  CG  . LYS A 1 369 ? 150.103 185.060 168.112 1.00 67.28  0  368 LYS A CG  1 
ATOM   2924 C  CD  . LYS A 1 369 ? 151.377 185.838 168.397 1.00 67.28  0  368 LYS A CD  1 
ATOM   2925 C  CE  . LYS A 1 369 ? 151.083 187.116 169.167 1.00 67.28  0  368 LYS A CE  1 
ATOM   2926 N  NZ  . LYS A 1 369 ? 150.318 188.095 168.347 1.00 67.28  1  368 LYS A NZ  1 
ATOM   2927 N  N   . ARG A 1 370 ? 148.445 183.612 164.941 1.00 67.28  0  369 ARG A N   1 
ATOM   2928 C  CA  . ARG A 1 370 ? 147.531 184.281 164.023 1.00 67.28  0  369 ARG A CA  1 
ATOM   2929 C  C   . ARG A 1 370 ? 146.208 183.532 163.904 1.00 67.28  0  369 ARG A C   1 
ATOM   2930 O  O   . ARG A 1 370 ? 145.156 184.164 163.755 1.00 67.28  0  369 ARG A O   1 
ATOM   2931 C  CB  . ARG A 1 370 ? 148.192 184.461 162.653 1.00 67.28  0  369 ARG A CB  1 
ATOM   2932 C  CG  . ARG A 1 370 ? 147.943 183.345 161.651 1.00 67.28  0  369 ARG A CG  1 
ATOM   2933 C  CD  . ARG A 1 370 ? 148.465 183.720 160.274 1.00 67.28  0  369 ARG A CD  1 
ATOM   2934 N  NE  . ARG A 1 370 ? 149.921 183.791 160.244 1.00 67.28  0  369 ARG A NE  1 
ATOM   2935 C  CZ  . ARG A 1 370 ? 150.630 184.209 159.204 1.00 67.28  0  369 ARG A CZ  1 
ATOM   2936 N  NH1 . ARG A 1 370 ? 150.047 184.604 158.084 1.00 67.28  1  369 ARG A NH1 1 
ATOM   2937 N  NH2 . ARG A 1 370 ? 151.957 184.230 159.290 1.00 67.28  0  369 ARG A NH2 1 
ATOM   2938 N  N   . LEU A 1 371 ? 146.232 182.199 163.990 1.00 67.28  0  370 LEU A N   1 
ATOM   2939 C  CA  . LEU A 1 371 ? 144.987 181.438 163.975 1.00 67.28  0  370 LEU A CA  1 
ATOM   2940 C  C   . LEU A 1 371 ? 144.142 181.749 165.202 1.00 67.28  0  370 LEU A C   1 
ATOM   2941 O  O   . LEU A 1 371 ? 142.914 181.865 165.108 1.00 67.28  0  370 LEU A O   1 
ATOM   2942 C  CB  . LEU A 1 371 ? 145.283 179.941 163.892 1.00 67.28  0  370 LEU A CB  1 
ATOM   2943 C  CG  . LEU A 1 371 ? 145.724 179.402 162.531 1.00 67.28  0  370 LEU A CG  1 
ATOM   2944 C  CD1 . LEU A 1 371 ? 146.188 177.961 162.652 1.00 67.28  0  370 LEU A CD1 1 
ATOM   2945 C  CD2 . LEU A 1 371 ? 144.599 179.521 161.519 1.00 67.28  0  370 LEU A CD2 1 
ATOM   2946 N  N   . LEU A 1 372 ? 144.780 181.880 166.366 1.00 67.28  0  371 LEU A N   1 
ATOM   2947 C  CA  . LEU A 1 372 ? 144.040 182.230 167.574 1.00 67.28  0  371 LEU A CA  1 
ATOM   2948 C  C   . LEU A 1 372 ? 143.547 183.672 167.524 1.00 67.28  0  371 LEU A C   1 
ATOM   2949 O  O   . LEU A 1 372 ? 142.450 183.974 168.007 1.00 67.28  0  371 LEU A O   1 
ATOM   2950 C  CB  . LEU A 1 372 ? 144.909 181.998 168.809 1.00 67.28  0  371 LEU A CB  1 
ATOM   2951 C  CG  . LEU A 1 372 ? 145.128 180.540 169.219 1.00 67.28  0  371 LEU A CG  1 
ATOM   2952 C  CD1 . LEU A 1 372 ? 145.524 180.451 170.684 1.00 67.28  0  371 LEU A CD1 1 
ATOM   2953 C  CD2 . LEU A 1 372 ? 143.885 179.707 168.947 1.00 67.28  0  371 LEU A CD2 1 
ATOM   2954 N  N   . ALA A 1 373 ? 144.344 184.577 166.951 1.00 67.28  0  372 ALA A N   1 
ATOM   2955 C  CA  . ALA A 1 373 ? 143.933 185.974 166.857 1.00 67.28  0  372 ALA A CA  1 
ATOM   2956 C  C   . ALA A 1 373 ? 142.732 186.133 165.933 1.00 67.28  0  372 ALA A C   1 
ATOM   2957 O  O   . ALA A 1 373 ? 141.734 186.764 166.299 1.00 67.28  0  372 ALA A O   1 
ATOM   2958 C  CB  . ALA A 1 373 ? 145.103 186.834 166.378 1.00 67.28  0  372 ALA A CB  1 
ATOM   2959 N  N   . GLU A 1 374 ? 142.808 185.568 164.732 1.00 67.66  0  373 GLU A N   1 
ATOM   2960 C  CA  . GLU A 1 374 ? 141.680 185.573 163.813 1.00 67.66  0  373 GLU A CA  1 
ATOM   2961 C  C   . GLU A 1 374 ? 140.732 184.436 164.188 1.00 67.66  0  373 GLU A C   1 
ATOM   2962 O  O   . GLU A 1 374 ? 140.869 183.798 165.236 1.00 67.66  0  373 GLU A O   1 
ATOM   2963 C  CB  . GLU A 1 374 ? 142.172 185.468 162.372 1.00 67.66  0  373 GLU A CB  1 
ATOM   2964 C  CG  . GLU A 1 374 ? 143.376 186.344 162.065 1.00 67.66  0  373 GLU A CG  1 
ATOM   2965 C  CD  . GLU A 1 374 ? 143.758 186.318 160.598 1.00 67.66  0  373 GLU A CD  1 
ATOM   2966 O  OE1 . GLU A 1 374 ? 143.448 185.317 159.919 1.00 67.66  0  373 GLU A OE1 1 
ATOM   2967 O  OE2 . GLU A 1 374 ? 144.368 187.300 160.125 1.00 67.66  -1 373 GLU A OE2 1 
ATOM   2968 N  N   . GLY A 1 375 ? 139.748 184.170 163.334 1.00 67.28  0  374 GLY A N   1 
ATOM   2969 C  CA  . GLY A 1 375 ? 138.829 183.083 163.594 1.00 67.28  0  374 GLY A CA  1 
ATOM   2970 C  C   . GLY A 1 375 ? 139.413 181.734 163.216 1.00 67.28  0  374 GLY A C   1 
ATOM   2971 O  O   . GLY A 1 375 ? 140.191 181.603 162.272 1.00 67.28  0  374 GLY A O   1 
ATOM   2972 N  N   . ILE A 1 376 ? 139.027 180.717 163.977 1.00 67.28  0  375 ILE A N   1 
ATOM   2973 C  CA  . ILE A 1 376 ? 139.438 179.348 163.688 1.00 67.28  0  375 ILE A CA  1 
ATOM   2974 C  C   . ILE A 1 376 ? 138.531 178.779 162.605 1.00 67.28  0  375 ILE A C   1 
ATOM   2975 O  O   . ILE A 1 376 ? 137.300 178.809 162.724 1.00 67.28  0  375 ILE A O   1 
ATOM   2976 C  CB  . ILE A 1 376 ? 139.406 178.487 164.961 1.00 67.28  0  375 ILE A CB  1 
ATOM   2977 C  CG1 . ILE A 1 376 ? 139.659 177.017 164.621 1.00 67.28  0  375 ILE A CG1 1 
ATOM   2978 C  CG2 . ILE A 1 376 ? 138.094 178.667 165.716 1.00 67.28  0  375 ILE A CG2 1 
ATOM   2979 C  CD1 . ILE A 1 376 ? 139.797 176.127 165.833 1.00 67.28  0  375 ILE A CD1 1 
ATOM   2980 N  N   . ASN A 1 377 ? 139.136 178.274 161.535 1.00 67.28  0  376 ASN A N   1 
ATOM   2981 C  CA  . ASN A 1 377 ? 138.383 177.708 160.427 1.00 67.28  0  376 ASN A CA  1 
ATOM   2982 C  C   . ASN A 1 377 ? 137.929 176.297 160.771 1.00 67.28  0  376 ASN A C   1 
ATOM   2983 O  O   . ASN A 1 377 ? 138.686 175.508 161.344 1.00 67.28  0  376 ASN A O   1 
ATOM   2984 C  CB  . ASN A 1 377 ? 139.227 177.695 159.153 1.00 67.28  0  376 ASN A CB  1 
ATOM   2985 C  CG  . ASN A 1 377 ? 138.437 177.262 157.934 1.00 67.28  0  376 ASN A CG  1 
ATOM   2986 O  OD1 . ASN A 1 377 ? 137.206 177.237 157.953 1.00 67.28  0  376 ASN A OD1 1 
ATOM   2987 N  ND2 . ASN A 1 377 ? 139.143 176.919 156.864 1.00 67.28  0  376 ASN A ND2 1 
ATOM   2988 N  N   . ARG A 1 378 ? 136.684 175.989 160.423 1.00 67.28  0  377 ARG A N   1 
ATOM   2989 C  CA  . ARG A 1 378 ? 136.133 174.679 160.730 1.00 67.28  0  377 ARG A CA  1 
ATOM   2990 C  C   . ARG A 1 378 ? 136.838 173.602 159.908 1.00 67.28  0  377 ARG A C   1 
ATOM   2991 O  O   . ARG A 1 378 ? 137.119 173.807 158.723 1.00 67.28  0  377 ARG A O   1 
ATOM   2992 C  CB  . ARG A 1 378 ? 134.630 174.647 160.455 1.00 67.28  0  377 ARG A CB  1 
ATOM   2993 C  CG  . ARG A 1 378 ? 133.829 175.715 161.194 1.00 67.28  0  377 ARG A CG  1 
ATOM   2994 C  CD  . ARG A 1 378 ? 133.955 175.641 162.727 1.00 67.28  0  377 ARG A CD  1 
ATOM   2995 N  NE  . ARG A 1 378 ? 134.192 174.308 163.278 1.00 67.28  0  377 ARG A NE  1 
ATOM   2996 C  CZ  . ARG A 1 378 ? 133.385 173.263 163.135 1.00 67.28  0  377 ARG A CZ  1 
ATOM   2997 N  NH1 . ARG A 1 378 ? 132.238 173.355 162.483 1.00 67.28  1  377 ARG A NH1 1 
ATOM   2998 N  NH2 . ARG A 1 378 ? 133.735 172.097 163.671 1.00 67.28  0  377 ARG A NH2 1 
ATOM   2999 N  N   . PRO A 1 379 ? 137.139 172.454 160.506 1.00 67.28  0  378 PRO A N   1 
ATOM   3000 C  CA  . PRO A 1 379 ? 137.751 171.361 159.745 1.00 67.28  0  378 PRO A CA  1 
ATOM   3001 C  C   . PRO A 1 379 ? 136.779 170.775 158.733 1.00 67.28  0  378 PRO A C   1 
ATOM   3002 O  O   . PRO A 1 379 ? 135.557 170.866 158.871 1.00 67.28  0  378 PRO A O   1 
ATOM   3003 C  CB  . PRO A 1 379 ? 138.112 170.336 160.824 1.00 67.28  0  378 PRO A CB  1 
ATOM   3004 C  CG  . PRO A 1 379 ? 137.183 170.636 161.949 1.00 67.28  0  378 PRO A CG  1 
ATOM   3005 C  CD  . PRO A 1 379 ? 136.970 172.117 161.928 1.00 67.28  0  378 PRO A CD  1 
ATOM   3006 N  N   . ARG A 1 380 ? 137.349 170.170 157.693 1.00 67.28  0  379 ARG A N   1 
ATOM   3007 C  CA  . ARG A 1 380 ? 136.535 169.569 156.645 1.00 67.28  0  379 ARG A CA  1 
ATOM   3008 C  C   . ARG A 1 380 ? 135.716 168.410 157.197 1.00 67.28  0  379 ARG A C   1 
ATOM   3009 O  O   . ARG A 1 380 ? 136.166 167.670 158.076 1.00 67.28  0  379 ARG A O   1 
ATOM   3010 C  CB  . ARG A 1 380 ? 137.419 169.085 155.496 1.00 67.28  0  379 ARG A CB  1 
ATOM   3011 C  CG  . ARG A 1 380 ? 137.968 170.194 154.621 1.00 67.28  0  379 ARG A CG  1 
ATOM   3012 C  CD  . ARG A 1 380 ? 138.966 169.651 153.615 1.00 67.28  0  379 ARG A CD  1 
ATOM   3013 N  NE  . ARG A 1 380 ? 138.472 168.453 152.948 1.00 67.28  0  379 ARG A NE  1 
ATOM   3014 C  CZ  . ARG A 1 380 ? 139.166 167.746 152.067 1.00 67.28  0  379 ARG A CZ  1 
ATOM   3015 N  NH1 . ARG A 1 380 ? 140.396 168.089 151.722 1.00 67.28  1  379 ARG A NH1 1 
ATOM   3016 N  NH2 . ARG A 1 380 ? 138.612 166.669 151.519 1.00 67.28  0  379 ARG A NH2 1 
ATOM   3017 N  N   . LYS A 1 381 ? 134.502 168.260 156.676 1.00 67.28  0  380 LYS A N   1 
ATOM   3018 C  CA  . LYS A 1 381 ? 133.635 167.168 157.095 1.00 67.28  0  380 LYS A CA  1 
ATOM   3019 C  C   . LYS A 1 381 ? 134.210 165.832 156.640 1.00 67.28  0  380 LYS A C   1 
ATOM   3020 O  O   . LYS A 1 381 ? 134.747 165.712 155.536 1.00 67.28  0  380 LYS A O   1 
ATOM   3021 C  CB  . LYS A 1 381 ? 132.229 167.366 156.526 1.00 67.28  0  380 LYS A CB  1 
ATOM   3022 C  CG  . LYS A 1 381 ? 131.220 166.313 156.948 1.00 67.28  0  380 LYS A CG  1 
ATOM   3023 C  CD  . LYS A 1 381 ? 129.830 166.651 156.430 1.00 67.28  0  380 LYS A CD  1 
ATOM   3024 C  CE  . LYS A 1 381 ? 128.841 165.534 156.717 1.00 67.28  0  380 LYS A CE  1 
ATOM   3025 N  NZ  . LYS A 1 381 ? 128.607 165.363 158.178 1.00 67.28  1  380 LYS A NZ  1 
ATOM   3026 N  N   . GLY A 1 382 ? 134.101 164.824 157.502 1.00 67.28  0  381 GLY A N   1 
ATOM   3027 C  CA  . GLY A 1 382 ? 134.645 163.517 157.191 1.00 67.28  0  381 GLY A CA  1 
ATOM   3028 C  C   . GLY A 1 382 ? 133.818 162.369 157.732 1.00 67.28  0  381 GLY A C   1 
ATOM   3029 O  O   . GLY A 1 382 ? 132.640 162.545 158.057 1.00 67.28  0  381 GLY A O   1 
ATOM   3030 N  N   . HIS A 1 383 ? 134.427 161.192 157.839 1.00 68.05  0  382 HIS A N   1 
ATOM   3031 C  CA  . HIS A 1 383 ? 133.707 160.005 158.273 1.00 68.05  0  382 HIS A CA  1 
ATOM   3032 C  C   . HIS A 1 383 ? 133.654 159.960 159.797 1.00 68.05  0  382 HIS A C   1 
ATOM   3033 O  O   . HIS A 1 383 ? 134.613 160.337 160.477 1.00 68.05  0  382 HIS A O   1 
ATOM   3034 C  CB  . HIS A 1 383 ? 134.380 158.749 157.716 1.00 68.05  0  382 HIS A CB  1 
ATOM   3035 C  CG  . HIS A 1 383 ? 133.616 157.489 157.969 1.00 68.05  0  382 HIS A CG  1 
ATOM   3036 N  ND1 . HIS A 1 383 ? 132.716 156.962 157.071 1.00 68.05  0  382 HIS A ND1 1 
ATOM   3037 C  CD2 . HIS A 1 383 ? 133.623 156.650 159.031 1.00 68.05  0  382 HIS A CD2 1 
ATOM   3038 C  CE1 . HIS A 1 383 ? 132.201 155.851 157.571 1.00 68.05  0  382 HIS A CE1 1 
ATOM   3039 N  NE2 . HIS A 1 383 ? 132.735 155.640 158.759 1.00 68.05  0  382 HIS A NE2 1 
ATOM   3040 N  N   . ASP A 1 384 ? 132.527 159.495 160.330 1.00 69.73  0  383 ASP A N   1 
ATOM   3041 C  CA  . ASP A 1 384 ? 132.196 159.584 161.753 1.00 69.73  0  383 ASP A CA  1 
ATOM   3042 C  C   . ASP A 1 384 ? 131.827 158.211 162.306 1.00 69.73  0  383 ASP A C   1 
ATOM   3043 O  O   . ASP A 1 384 ? 130.747 158.007 162.865 1.00 69.73  0  383 ASP A O   1 
ATOM   3044 C  CB  . ASP A 1 384 ? 131.071 160.593 161.983 1.00 69.73  0  383 ASP A CB  1 
ATOM   3045 C  CG  . ASP A 1 384 ? 130.998 161.070 163.424 1.00 69.73  0  383 ASP A CG  1 
ATOM   3046 O  OD1 . ASP A 1 384 ? 131.867 160.673 164.226 1.00 69.73  0  383 ASP A OD1 1 
ATOM   3047 O  OD2 . ASP A 1 384 ? 130.081 161.855 163.753 1.00 69.73  -1 383 ASP A OD2 1 
ATOM   3048 N  N   . ALA A 1 385 ? 132.728 157.239 162.141 1.00 69.18  0  384 ALA A N   1 
ATOM   3049 C  CA  . ALA A 1 385 ? 132.467 155.845 162.495 1.00 69.18  0  384 ALA A CA  1 
ATOM   3050 C  C   . ALA A 1 385 ? 132.041 155.640 163.946 1.00 69.18  0  384 ALA A C   1 
ATOM   3051 O  O   . ALA A 1 385 ? 131.604 154.544 164.311 1.00 69.18  0  384 ALA A O   1 
ATOM   3052 C  CB  . ALA A 1 385 ? 133.708 154.992 162.220 1.00 69.18  0  384 ALA A CB  1 
ATOM   3053 N  N   . GLY A 1 386 ? 132.156 156.674 164.778 1.00 69.13  0  385 GLY A N   1 
ATOM   3054 C  CA  . GLY A 1 386 ? 131.780 156.578 166.172 1.00 69.13  0  385 GLY A CA  1 
ATOM   3055 C  C   . GLY A 1 386 ? 132.885 156.135 167.103 1.00 69.13  0  385 GLY A C   1 
ATOM   3056 O  O   . GLY A 1 386 ? 132.643 156.003 168.310 1.00 69.13  0  385 GLY A O   1 
ATOM   3057 N  N   . ASP A 1 387 ? 134.087 155.904 166.582 1.00 68.69  0  386 ASP A N   1 
ATOM   3058 C  CA  . ASP A 1 387 ? 135.241 155.550 167.396 1.00 68.69  0  386 ASP A CA  1 
ATOM   3059 C  C   . ASP A 1 387 ? 135.820 156.792 168.060 1.00 68.69  0  386 ASP A C   1 
ATOM   3060 O  O   . ASP A 1 387 ? 135.169 157.841 168.103 1.00 68.69  0  386 ASP A O   1 
ATOM   3061 C  CB  . ASP A 1 387 ? 136.302 154.857 166.542 1.00 68.69  0  386 ASP A CB  1 
ATOM   3062 C  CG  . ASP A 1 387 ? 135.903 153.452 166.146 1.00 68.69  0  386 ASP A CG  1 
ATOM   3063 O  OD1 . ASP A 1 387 ? 135.097 152.834 166.873 1.00 68.69  0  386 ASP A OD1 1 
ATOM   3064 O  OD2 . ASP A 1 387 ? 136.403 152.963 165.112 1.00 68.69  -1 386 ASP A OD2 1 
ATOM   3065 N  N   . HIS A 1 388 ? 137.037 156.674 168.596 1.00 67.28  0  387 HIS A N   1 
ATOM   3066 C  CA  . HIS A 1 388 ? 137.698 157.796 169.241 1.00 67.28  0  387 HIS A CA  1 
ATOM   3067 C  C   . HIS A 1 388 ? 137.792 158.991 168.293 1.00 67.28  0  387 HIS A C   1 
ATOM   3068 O  O   . HIS A 1 388 ? 137.650 158.847 167.077 1.00 67.28  0  387 HIS A O   1 
ATOM   3069 C  CB  . HIS A 1 388 ? 139.103 157.399 169.695 1.00 67.28  0  387 HIS A CB  1 
ATOM   3070 C  CG  . HIS A 1 388 ? 139.148 156.174 170.554 1.00 67.28  0  387 HIS A CG  1 
ATOM   3071 N  ND1 . HIS A 1 388 ? 138.695 154.944 170.128 1.00 67.28  0  387 HIS A ND1 1 
ATOM   3072 C  CD2 . HIS A 1 388 ? 139.606 155.990 171.814 1.00 67.28  0  387 HIS A CD2 1 
ATOM   3073 C  CE1 . HIS A 1 388 ? 138.866 154.057 171.091 1.00 67.28  0  387 HIS A CE1 1 
ATOM   3074 N  NE2 . HIS A 1 388 ? 139.419 154.666 172.124 1.00 67.28  0  387 HIS A NE2 1 
ATOM   3075 N  N   . PRO A 1 389 ? 138.016 160.185 168.831 1.00 67.28  0  388 PRO A N   1 
ATOM   3076 C  CA  . PRO A 1 389 ? 138.334 161.332 167.981 1.00 67.28  0  388 PRO A CA  1 
ATOM   3077 C  C   . PRO A 1 389 ? 139.609 161.083 167.198 1.00 67.28  0  388 PRO A C   1 
ATOM   3078 O  O   . PRO A 1 389 ? 140.408 160.205 167.560 1.00 67.28  0  388 PRO A O   1 
ATOM   3079 C  CB  . PRO A 1 389 ? 138.511 162.476 168.990 1.00 67.28  0  388 PRO A CB  1 
ATOM   3080 C  CG  . PRO A 1 389 ? 137.652 162.093 170.130 1.00 67.28  0  388 PRO A CG  1 
ATOM   3081 C  CD  . PRO A 1 389 ? 137.716 160.593 170.215 1.00 67.28  0  388 PRO A CD  1 
ATOM   3082 N  N   . PRO A 1 390 ? 139.837 161.828 166.118 1.00 67.28  0  389 PRO A N   1 
ATOM   3083 C  CA  . PRO A 1 390 ? 141.038 161.605 165.306 1.00 67.28  0  389 PRO A CA  1 
ATOM   3084 C  C   . PRO A 1 390 ? 142.312 161.853 166.099 1.00 67.28  0  389 PRO A C   1 
ATOM   3085 O  O   . PRO A 1 390 ? 142.307 162.470 167.167 1.00 67.28  0  389 PRO A O   1 
ATOM   3086 C  CB  . PRO A 1 390 ? 140.887 162.615 164.163 1.00 67.28  0  389 PRO A CB  1 
ATOM   3087 C  CG  . PRO A 1 390 ? 139.426 162.919 164.118 1.00 67.28  0  389 PRO A CG  1 
ATOM   3088 C  CD  . PRO A 1 390 ? 138.957 162.852 165.532 1.00 67.28  0  389 PRO A CD  1 
ATOM   3089 N  N   . ILE A 1 391 ? 143.421 161.354 165.557 1.00 67.28  0  390 ILE A N   1 
ATOM   3090 C  CA  . ILE A 1 391 ? 144.710 161.435 166.236 1.00 67.28  0  390 ILE A CA  1 
ATOM   3091 C  C   . ILE A 1 391 ? 145.127 162.901 166.285 1.00 67.28  0  390 ILE A C   1 
ATOM   3092 O  O   . ILE A 1 391 ? 145.533 163.476 165.271 1.00 67.28  0  390 ILE A O   1 
ATOM   3093 C  CB  . ILE A 1 391 ? 145.768 160.576 165.537 1.00 67.28  0  390 ILE A CB  1 
ATOM   3094 C  CG1 . ILE A 1 391 ? 145.187 159.207 165.183 1.00 67.28  0  390 ILE A CG1 1 
ATOM   3095 C  CG2 . ILE A 1 391 ? 146.995 160.421 166.420 1.00 67.28  0  390 ILE A CG2 1 
ATOM   3096 C  CD1 . ILE A 1 391 ? 146.074 158.379 164.284 1.00 67.28  0  390 ILE A CD1 1 
ATOM   3097 N  N   . THR A 1 392 ? 145.032 163.506 167.464 1.00 67.28  0  391 THR A N   1 
ATOM   3098 C  CA  . THR A 1 392 ? 145.267 164.927 167.644 1.00 67.28  0  391 THR A CA  1 
ATOM   3099 C  C   . THR A 1 392 ? 146.164 165.171 168.846 1.00 67.28  0  391 THR A C   1 
ATOM   3100 O  O   . THR A 1 392 ? 146.181 164.373 169.789 1.00 67.28  0  391 THR A O   1 
ATOM   3101 C  CB  . THR A 1 392 ? 143.945 165.683 167.838 1.00 67.28  0  391 THR A CB  1 
ATOM   3102 O  OG1 . THR A 1 392 ? 143.195 165.074 168.896 1.00 67.28  0  391 THR A OG1 1 
ATOM   3103 C  CG2 . THR A 1 392 ? 143.134 165.646 166.565 1.00 67.28  0  391 THR A CG2 1 
ATOM   3104 N  N   . PRO A 1 393 ? 146.925 166.264 168.837 1.00 67.28  0  392 PRO A N   1 
ATOM   3105 C  CA  . PRO A 1 393 ? 147.752 166.595 170.001 1.00 67.28  0  392 PRO A CA  1 
ATOM   3106 C  C   . PRO A 1 393 ? 146.896 166.913 171.217 1.00 67.28  0  392 PRO A C   1 
ATOM   3107 O  O   . PRO A 1 393 ? 145.780 167.425 171.104 1.00 67.28  0  392 PRO A O   1 
ATOM   3108 C  CB  . PRO A 1 393 ? 148.541 167.826 169.541 1.00 67.28  0  392 PRO A CB  1 
ATOM   3109 C  CG  . PRO A 1 393 ? 148.438 167.823 168.057 1.00 67.28  0  392 PRO A CG  1 
ATOM   3110 C  CD  . PRO A 1 393 ? 147.120 167.217 167.735 1.00 67.28  0  392 PRO A CD  1 
ATOM   3111 N  N   . MET A 1 394 ? 147.437 166.601 172.394 1.00 67.28  0  393 MET A N   1 
ATOM   3112 C  CA  . MET A 1 394 ? 146.771 166.905 173.650 1.00 67.28  0  393 MET A CA  1 
ATOM   3113 C  C   . MET A 1 394 ? 147.692 167.544 174.679 1.00 67.28  0  393 MET A C   1 
ATOM   3114 O  O   . MET A 1 394 ? 147.214 167.944 175.745 1.00 67.28  0  393 MET A O   1 
ATOM   3115 C  CB  . MET A 1 394 ? 146.145 165.636 174.248 1.00 67.28  0  393 MET A CB  1 
ATOM   3116 C  CG  . MET A 1 394 ? 144.950 165.109 173.472 1.00 67.28  0  393 MET A CG  1 
ATOM   3117 S  SD  . MET A 1 394 ? 143.565 166.262 173.464 1.00 67.28  0  393 MET A SD  1 
ATOM   3118 C  CE  . MET A 1 394 ? 142.186 165.132 173.301 1.00 67.28  0  393 MET A CE  1 
ATOM   3119 N  N   . LYS A 1 395 ? 148.987 167.653 174.394 1.00 67.28  0  394 LYS A N   1 
ATOM   3120 C  CA  . LYS A 1 395 ? 149.929 168.254 175.326 1.00 67.28  0  394 LYS A CA  1 
ATOM   3121 C  C   . LYS A 1 395 ? 151.133 168.757 174.547 1.00 67.28  0  394 LYS A C   1 
ATOM   3122 O  O   . LYS A 1 395 ? 151.532 168.159 173.544 1.00 67.28  0  394 LYS A O   1 
ATOM   3123 C  CB  . LYS A 1 395 ? 150.365 167.255 176.404 1.00 67.28  0  394 LYS A CB  1 
ATOM   3124 C  CG  . LYS A 1 395 ? 150.927 167.896 177.660 1.00 67.28  0  394 LYS A CG  1 
ATOM   3125 C  CD  . LYS A 1 395 ? 151.839 166.937 178.405 1.00 67.28  0  394 LYS A CD  1 
ATOM   3126 C  CE  . LYS A 1 395 ? 151.093 165.684 178.832 1.00 67.28  0  394 LYS A CE  1 
ATOM   3127 N  NZ  . LYS A 1 395 ? 149.808 166.006 179.510 1.00 67.28  1  394 LYS A NZ  1 
ATOM   3128 N  N   . SER A 1 396 ? 151.703 169.862 175.017 1.00 67.28  0  395 SER A N   1 
ATOM   3129 C  CA  . SER A 1 396 ? 152.874 170.433 174.367 1.00 67.28  0  395 SER A CA  1 
ATOM   3130 C  C   . SER A 1 396 ? 154.083 169.527 174.558 1.00 67.28  0  395 SER A C   1 
ATOM   3131 O  O   . SER A 1 396 ? 154.296 168.967 175.637 1.00 67.28  0  395 SER A O   1 
ATOM   3132 C  CB  . SER A 1 396 ? 153.167 171.824 174.925 1.00 67.28  0  395 SER A CB  1 
ATOM   3133 O  OG  . SER A 1 396 ? 153.643 171.748 176.257 1.00 67.28  0  395 SER A OG  1 
ATOM   3134 N  N   . ALA A 1 397 ? 154.878 169.383 173.501 1.00 67.28  0  396 ALA A N   1 
ATOM   3135 C  CA  . ALA A 1 397 ? 156.064 168.545 173.545 1.00 67.28  0  396 ALA A CA  1 
ATOM   3136 C  C   . ALA A 1 397 ? 157.196 169.213 172.780 1.00 67.28  0  396 ALA A C   1 
ATOM   3137 O  O   . ALA A 1 397 ? 156.971 169.944 171.812 1.00 67.28  0  396 ALA A O   1 
ATOM   3138 C  CB  . ALA A 1 397 ? 155.796 167.147 172.972 1.00 67.28  0  396 ALA A CB  1 
ATOM   3139 N  N   . THR A 1 398 ? 158.418 168.950 173.232 1.00 67.28  0  397 THR A N   1 
ATOM   3140 C  CA  . THR A 1 398 ? 159.626 169.475 172.619 1.00 67.28  0  397 THR A CA  1 
ATOM   3141 C  C   . THR A 1 398 ? 160.565 168.309 172.342 1.00 67.28  0  397 THR A C   1 
ATOM   3142 O  O   . THR A 1 398 ? 160.485 167.259 172.985 1.00 67.28  0  397 THR A O   1 
ATOM   3143 C  CB  . THR A 1 398 ? 160.297 170.523 173.527 1.00 67.28  0  397 THR A CB  1 
ATOM   3144 O  OG1 . THR A 1 398 ? 159.333 171.517 173.896 1.00 67.28  0  397 THR A OG1 1 
ATOM   3145 C  CG2 . THR A 1 398 ? 161.450 171.216 172.814 1.00 67.28  0  397 THR A CG2 1 
ATOM   3146 N  N   . GLU A 1 399 ? 161.449 168.495 171.356 1.00 67.28  0  398 GLU A N   1 
ATOM   3147 C  CA  . GLU A 1 399 ? 162.401 167.447 170.999 1.00 67.28  0  398 GLU A CA  1 
ATOM   3148 C  C   . GLU A 1 399 ? 163.239 167.011 172.195 1.00 67.28  0  398 GLU A C   1 
ATOM   3149 O  O   . GLU A 1 399 ? 163.679 165.857 172.256 1.00 67.28  0  398 GLU A O   1 
ATOM   3150 C  CB  . GLU A 1 399 ? 163.305 167.928 169.864 1.00 67.28  0  398 GLU A CB  1 
ATOM   3151 C  CG  . GLU A 1 399 ? 164.175 166.842 169.252 1.00 67.28  0  398 GLU A CG  1 
ATOM   3152 C  CD  . GLU A 1 399 ? 164.656 167.196 167.859 1.00 67.28  0  398 GLU A CD  1 
ATOM   3153 O  OE1 . GLU A 1 399 ? 164.186 168.213 167.306 1.00 67.28  0  398 GLU A OE1 1 
ATOM   3154 O  OE2 . GLU A 1 399 ? 165.504 166.458 167.316 1.00 67.28  -1 398 GLU A OE2 1 
ATOM   3155 N  N   . ALA A 1 400 ? 163.474 167.913 173.150 1.00 67.28  0  399 ALA A N   1 
ATOM   3156 C  CA  . ALA A 1 400 ? 164.254 167.557 174.330 1.00 67.28  0  399 ALA A CA  1 
ATOM   3157 C  C   . ALA A 1 400 ? 163.517 166.543 175.198 1.00 67.28  0  399 ALA A C   1 
ATOM   3158 O  O   . ALA A 1 400 ? 164.095 165.531 175.612 1.00 67.28  0  399 ALA A O   1 
ATOM   3159 C  CB  . ALA A 1 400 ? 164.589 168.813 175.135 1.00 67.28  0  399 ALA A CB  1 
ATOM   3160 N  N   . GLU A 1 401 ? 162.237 166.794 175.485 1.00 67.28  0  400 GLU A N   1 
ATOM   3161 C  CA  . GLU A 1 401 ? 161.489 165.884 176.346 1.00 67.28  0  400 GLU A CA  1 
ATOM   3162 C  C   . GLU A 1 401 ? 161.077 164.613 175.615 1.00 67.28  0  400 GLU A C   1 
ATOM   3163 O  O   . GLU A 1 401 ? 160.947 163.558 176.245 1.00 67.28  0  400 GLU A O   1 
ATOM   3164 C  CB  . GLU A 1 401 ? 160.265 166.591 176.934 1.00 67.28  0  400 GLU A CB  1 
ATOM   3165 C  CG  . GLU A 1 401 ? 159.114 166.813 175.969 1.00 67.28  0  400 GLU A CG  1 
ATOM   3166 C  CD  . GLU A 1 401 ? 158.131 167.850 176.476 1.00 67.28  0  400 GLU A CD  1 
ATOM   3167 O  OE1 . GLU A 1 401 ? 158.578 168.940 176.894 1.00 67.28  0  400 GLU A OE1 1 
ATOM   3168 O  OE2 . GLU A 1 401 ? 156.914 167.571 176.472 1.00 67.28  -1 400 GLU A OE2 1 
ATOM   3169 N  N   . LEU A 1 402 ? 160.865 164.688 174.305 1.00 67.28  0  401 LEU A N   1 
ATOM   3170 C  CA  . LEU A 1 402 ? 160.615 163.507 173.496 1.00 67.28  0  401 LEU A CA  1 
ATOM   3171 C  C   . LEU A 1 402 ? 161.949 162.967 172.982 1.00 67.28  0  401 LEU A C   1 
ATOM   3172 O  O   . LEU A 1 402 ? 163.023 163.375 173.432 1.00 67.28  0  401 LEU A O   1 
ATOM   3173 C  CB  . LEU A 1 402 ? 159.644 163.833 172.364 1.00 67.28  0  401 LEU A CB  1 
ATOM   3174 C  CG  . LEU A 1 402 ? 158.160 163.739 172.720 1.00 67.28  0  401 LEU A CG  1 
ATOM   3175 C  CD1 . LEU A 1 402 ? 157.293 164.018 171.505 1.00 67.28  0  401 LEU A CD1 1 
ATOM   3176 C  CD2 . LEU A 1 402 ? 157.838 162.377 173.311 1.00 67.28  0  401 LEU A CD2 1 
ATOM   3177 N  N   . GLY A 1 403 ? 161.897 162.035 172.036 1.00 67.28  0  402 GLY A N   1 
ATOM   3178 C  CA  . GLY A 1 403 ? 163.114 161.444 171.517 1.00 67.28  0  402 GLY A CA  1 
ATOM   3179 C  C   . GLY A 1 403 ? 163.336 161.646 170.033 1.00 67.28  0  402 GLY A C   1 
ATOM   3180 O  O   . GLY A 1 403 ? 163.510 162.775 169.564 1.00 67.28  0  402 GLY A O   1 
ATOM   3181 N  N   . GLY A 1 404 ? 163.331 160.546 169.287 1.00 67.28  0  403 GLY A N   1 
ATOM   3182 C  CA  . GLY A 1 404 ? 163.612 160.552 167.865 1.00 67.28  0  403 GLY A CA  1 
ATOM   3183 C  C   . GLY A 1 404 ? 162.376 160.375 167.009 1.00 67.28  0  403 GLY A C   1 
ATOM   3184 O  O   . GLY A 1 404 ? 161.689 161.348 166.676 1.00 67.28  0  403 GLY A O   1 
ATOM   3185 N  N   . ASP A 1 405 ? 162.129 159.130 166.594 1.00 67.28  0  404 ASP A N   1 
ATOM   3186 C  CA  . ASP A 1 405 ? 160.943 158.821 165.804 1.00 67.28  0  404 ASP A CA  1 
ATOM   3187 C  C   . ASP A 1 405 ? 159.664 159.253 166.510 1.00 67.28  0  404 ASP A C   1 
ATOM   3188 O  O   . ASP A 1 405 ? 158.702 159.661 165.850 1.00 67.28  0  404 ASP A O   1 
ATOM   3189 C  CB  . ASP A 1 405 ? 160.899 157.325 165.497 1.00 67.28  0  404 ASP A CB  1 
ATOM   3190 C  CG  . ASP A 1 405 ? 161.983 156.898 164.528 1.00 67.28  0  404 ASP A CG  1 
ATOM   3191 O  OD1 . ASP A 1 405 ? 162.366 157.713 163.663 1.00 67.28  0  404 ASP A OD1 1 
ATOM   3192 O  OD2 . ASP A 1 405 ? 162.454 155.746 164.633 1.00 67.28  -1 404 ASP A OD2 1 
ATOM   3193 N  N   . ALA A 1 406 ? 159.628 159.165 167.842 1.00 67.28  0  405 ALA A N   1 
ATOM   3194 C  CA  . ALA A 1 406 ? 158.454 159.625 168.576 1.00 67.28  0  405 ALA A CA  1 
ATOM   3195 C  C   . ALA A 1 406 ? 158.239 161.121 168.387 1.00 67.28  0  405 ALA A C   1 
ATOM   3196 O  O   . ALA A 1 406 ? 157.112 161.569 168.138 1.00 67.28  0  405 ALA A O   1 
ATOM   3197 C  CB  . ALA A 1 406 ? 158.594 159.285 170.059 1.00 67.28  0  405 ALA A CB  1 
ATOM   3198 N  N   . TRP A 1 407 ? 159.312 161.909 168.486 1.00 67.28  0  406 TRP A N   1 
ATOM   3199 C  CA  . TRP A 1 407 ? 159.196 163.344 168.250 1.00 67.28  0  406 TRP A CA  1 
ATOM   3200 C  C   . TRP A 1 407 ? 158.800 163.639 166.811 1.00 67.28  0  406 TRP A C   1 
ATOM   3201 O  O   . TRP A 1 407 ? 158.027 164.565 166.553 1.00 67.28  0  406 TRP A O   1 
ATOM   3202 C  CB  . TRP A 1 407 ? 160.505 164.052 168.593 1.00 67.28  0  406 TRP A CB  1 
ATOM   3203 C  CG  . TRP A 1 407 ? 160.577 165.429 168.012 1.00 67.28  0  406 TRP A CG  1 
ATOM   3204 C  CD1 . TRP A 1 407 ? 161.423 165.860 167.035 1.00 67.28  0  406 TRP A CD1 1 
ATOM   3205 C  CD2 . TRP A 1 407 ? 159.742 166.544 168.341 1.00 67.28  0  406 TRP A CD2 1 
ATOM   3206 N  NE1 . TRP A 1 407 ? 161.182 167.181 166.749 1.00 67.28  0  406 TRP A NE1 1 
ATOM   3207 C  CE2 . TRP A 1 407 ? 160.153 167.623 167.536 1.00 67.28  0  406 TRP A CE2 1 
ATOM   3208 C  CE3 . TRP A 1 407 ? 158.693 166.737 169.243 1.00 67.28  0  406 TRP A CE3 1 
ATOM   3209 C  CZ2 . TRP A 1 407 ? 159.553 168.876 167.607 1.00 67.28  0  406 TRP A CZ2 1 
ATOM   3210 C  CZ3 . TRP A 1 407 ? 158.099 167.981 169.312 1.00 67.28  0  406 TRP A CZ3 1 
ATOM   3211 C  CH2 . TRP A 1 407 ? 158.529 169.033 168.499 1.00 67.28  0  406 TRP A CH2 1 
ATOM   3212 N  N   . ARG A 1 408 ? 159.336 162.875 165.859 1.00 67.28  0  407 ARG A N   1 
ATOM   3213 C  CA  . ARG A 1 408 ? 158.978 163.090 164.459 1.00 67.28  0  407 ARG A CA  1 
ATOM   3214 C  C   . ARG A 1 408 ? 157.496 162.818 164.218 1.00 67.28  0  407 ARG A C   1 
ATOM   3215 O  O   . ARG A 1 408 ? 156.814 163.591 163.529 1.00 67.28  0  407 ARG A O   1 
ATOM   3216 C  CB  . ARG A 1 408 ? 159.844 162.210 163.559 1.00 67.28  0  407 ARG A CB  1 
ATOM   3217 C  CG  . ARG A 1 408 ? 161.310 162.605 163.539 1.00 67.28  0  407 ARG A CG  1 
ATOM   3218 C  CD  . ARG A 1 408 ? 161.851 162.662 162.121 1.00 67.28  0  407 ARG A CD  1 
ATOM   3219 N  NE  . ARG A 1 408 ? 161.840 161.354 161.476 1.00 67.28  0  407 ARG A NE  1 
ATOM   3220 C  CZ  . ARG A 1 408 ? 162.704 160.382 161.735 1.00 67.28  0  407 ARG A CZ  1 
ATOM   3221 N  NH1 . ARG A 1 408 ? 163.677 160.538 162.618 1.00 67.28  1  407 ARG A NH1 1 
ATOM   3222 N  NH2 . ARG A 1 408 ? 162.591 159.225 161.090 1.00 67.28  0  407 ARG A NH2 1 
ATOM   3223 N  N   . LEU A 1 409 ? 156.978 161.727 164.787 1.00 67.28  0  408 LEU A N   1 
ATOM   3224 C  CA  . LEU A 1 409 ? 155.559 161.417 164.649 1.00 67.28  0  408 LEU A CA  1 
ATOM   3225 C  C   . LEU A 1 409 ? 154.695 162.475 165.324 1.00 67.28  0  408 LEU A C   1 
ATOM   3226 O  O   . LEU A 1 409 ? 153.655 162.873 164.783 1.00 67.28  0  408 LEU A O   1 
ATOM   3227 C  CB  . LEU A 1 409 ? 155.265 160.034 165.227 1.00 67.28  0  408 LEU A CB  1 
ATOM   3228 C  CG  . LEU A 1 409 ? 153.966 159.372 164.770 1.00 67.28  0  408 LEU A CG  1 
ATOM   3229 C  CD1 . LEU A 1 409 ? 153.933 159.251 163.257 1.00 67.28  0  408 LEU A CD1 1 
ATOM   3230 C  CD2 . LEU A 1 409 ? 153.800 158.011 165.423 1.00 67.28  0  408 LEU A CD2 1 
ATOM   3231 N  N   . TYR A 1 410 ? 155.110 162.943 166.504 1.00 67.28  0  409 TYR A N   1 
ATOM   3232 C  CA  . TYR A 1 410 ? 154.372 164.011 167.170 1.00 67.28  0  409 TYR A CA  1 
ATOM   3233 C  C   . TYR A 1 410 ? 154.371 165.280 166.329 1.00 67.28  0  409 TYR A C   1 
ATOM   3234 O  O   . TYR A 1 410 ? 153.346 165.963 166.226 1.00 67.28  0  409 TYR A O   1 
ATOM   3235 C  CB  . TYR A 1 410 ? 154.968 164.281 168.550 1.00 67.28  0  409 TYR A CB  1 
ATOM   3236 C  CG  . TYR A 1 410 ? 154.276 165.388 169.313 1.00 67.28  0  409 TYR A CG  1 
ATOM   3237 C  CD1 . TYR A 1 410 ? 153.132 165.137 170.055 1.00 67.28  0  409 TYR A CD1 1 
ATOM   3238 C  CD2 . TYR A 1 410 ? 154.773 166.683 169.296 1.00 67.28  0  409 TYR A CD2 1 
ATOM   3239 C  CE1 . TYR A 1 410 ? 152.499 166.146 170.753 1.00 67.28  0  409 TYR A CE1 1 
ATOM   3240 C  CE2 . TYR A 1 410 ? 154.147 167.697 169.991 1.00 67.28  0  409 TYR A CE2 1 
ATOM   3241 C  CZ  . TYR A 1 410 ? 153.011 167.423 170.719 1.00 67.28  0  409 TYR A CZ  1 
ATOM   3242 O  OH  . TYR A 1 410 ? 152.383 168.431 171.414 1.00 67.28  0  409 TYR A OH  1 
ATOM   3243 N  N   . GLU A 1 411 ? 155.513 165.612 165.726 1.00 67.28  0  410 GLU A N   1 
ATOM   3244 C  CA  . GLU A 1 411 ? 155.592 166.791 164.874 1.00 67.28  0  410 GLU A CA  1 
ATOM   3245 C  C   . GLU A 1 411 ? 154.646 166.672 163.691 1.00 67.28  0  410 GLU A C   1 
ATOM   3246 O  O   . GLU A 1 411 ? 153.941 167.631 163.353 1.00 67.28  0  410 GLU A O   1 
ATOM   3247 C  CB  . GLU A 1 411 ? 157.030 166.995 164.396 1.00 67.28  0  410 GLU A CB  1 
ATOM   3248 C  CG  . GLU A 1 411 ? 157.197 168.102 163.371 1.00 67.28  0  410 GLU A CG  1 
ATOM   3249 C  CD  . GLU A 1 411 ? 158.640 168.290 162.944 1.00 67.28  0  410 GLU A CD  1 
ATOM   3250 O  OE1 . GLU A 1 411 ? 159.529 168.274 163.821 1.00 67.28  0  410 GLU A OE1 1 
ATOM   3251 O  OE2 . GLU A 1 411 ? 158.886 168.455 161.731 1.00 67.28  -1 410 GLU A OE2 1 
ATOM   3252 N  N   . TYR A 1 412 ? 154.604 165.499 163.055 1.00 67.28  0  411 TYR A N   1 
ATOM   3253 C  CA  . TYR A 1 412 ? 153.673 165.320 161.945 1.00 67.28  0  411 TYR A CA  1 
ATOM   3254 C  C   . TYR A 1 412 ? 152.226 165.443 162.406 1.00 67.28  0  411 TYR A C   1 
ATOM   3255 O  O   . TYR A 1 412 ? 151.400 166.045 161.712 1.00 67.28  0  411 TYR A O   1 
ATOM   3256 C  CB  . TYR A 1 412 ? 153.882 163.977 161.251 1.00 67.28  0  411 TYR A CB  1 
ATOM   3257 C  CG  . TYR A 1 412 ? 152.808 163.736 160.218 1.00 67.28  0  411 TYR A CG  1 
ATOM   3258 C  CD1 . TYR A 1 412 ? 152.669 164.586 159.130 1.00 67.28  0  411 TYR A CD1 1 
ATOM   3259 C  CD2 . TYR A 1 412 ? 151.903 162.694 160.353 1.00 67.28  0  411 TYR A CD2 1 
ATOM   3260 C  CE1 . TYR A 1 412 ? 151.678 164.391 158.193 1.00 67.28  0  411 TYR A CE1 1 
ATOM   3261 C  CE2 . TYR A 1 412 ? 150.906 162.490 159.419 1.00 67.28  0  411 TYR A CE2 1 
ATOM   3262 C  CZ  . TYR A 1 412 ? 150.799 163.343 158.342 1.00 67.28  0  411 TYR A CZ  1 
ATOM   3263 O  OH  . TYR A 1 412 ? 149.809 163.150 157.406 1.00 67.28  0  411 TYR A OH  1 
ATOM   3264 N  N   . ILE A 1 413 ? 151.895 164.870 163.566 1.00 67.28  0  412 ILE A N   1 
ATOM   3265 C  CA  . ILE A 1 413 ? 150.514 164.918 164.046 1.00 67.28  0  412 ILE A CA  1 
ATOM   3266 C  C   . ILE A 1 413 ? 150.096 166.357 164.328 1.00 67.28  0  412 ILE A C   1 
ATOM   3267 O  O   . ILE A 1 413 ? 149.008 166.799 163.934 1.00 67.28  0  412 ILE A O   1 
ATOM   3268 C  CB  . ILE A 1 413 ? 150.346 164.024 165.288 1.00 67.28  0  412 ILE A CB  1 
ATOM   3269 C  CG1 . ILE A 1 413 ? 150.311 162.551 164.883 1.00 67.28  0  412 ILE A CG1 1 
ATOM   3270 C  CG2 . ILE A 1 413 ? 149.085 164.394 166.052 1.00 67.28  0  412 ILE A CG2 1 
ATOM   3271 C  CD1 . ILE A 1 413 ? 150.535 161.598 166.032 1.00 67.28  0  412 ILE A CD1 1 
ATOM   3272 N  N   . THR A 1 414 ? 150.961 167.114 165.008 1.00 67.28  0  413 THR A N   1 
ATOM   3273 C  CA  . THR A 1 414 ? 150.655 168.515 165.279 1.00 67.28  0  413 THR A CA  1 
ATOM   3274 C  C   . THR A 1 414 ? 150.551 169.331 164.000 1.00 67.28  0  413 THR A C   1 
ATOM   3275 O  O   . THR A 1 414 ? 149.661 170.182 163.881 1.00 67.28  0  413 THR A O   1 
ATOM   3276 C  CB  . THR A 1 414 ? 151.708 169.126 166.201 1.00 67.28  0  413 THR A CB  1 
ATOM   3277 O  OG1 . THR A 1 414 ? 152.959 169.221 165.508 1.00 67.28  0  413 THR A OG1 1 
ATOM   3278 C  CG2 . THR A 1 414 ? 151.872 168.293 167.452 1.00 67.28  0  413 THR A CG2 1 
ATOM   3279 N  N   . ARG A 1 415 ? 151.447 169.097 163.040 1.00 67.28  0  414 ARG A N   1 
ATOM   3280 C  CA  . ARG A 1 415 ? 151.380 169.829 161.783 1.00 67.28  0  414 ARG A CA  1 
ATOM   3281 C  C   . ARG A 1 415 ? 150.092 169.513 161.035 1.00 67.28  0  414 ARG A C   1 
ATOM   3282 O  O   . ARG A 1 415 ? 149.469 170.408 160.453 1.00 67.28  0  414 ARG A O   1 
ATOM   3283 C  CB  . ARG A 1 415 ? 152.607 169.509 160.931 1.00 67.28  0  414 ARG A CB  1 
ATOM   3284 C  CG  . ARG A 1 415 ? 153.852 170.262 161.374 1.00 67.28  0  414 ARG A CG  1 
ATOM   3285 C  CD  . ARG A 1 415 ? 155.049 169.965 160.493 1.00 67.28  0  414 ARG A CD  1 
ATOM   3286 N  NE  . ARG A 1 415 ? 156.256 170.604 161.001 1.00 67.28  0  414 ARG A NE  1 
ATOM   3287 C  CZ  . ARG A 1 415 ? 156.699 171.789 160.604 1.00 67.28  0  414 ARG A CZ  1 
ATOM   3288 N  NH1 . ARG A 1 415 ? 156.053 172.498 159.693 1.00 67.28  1  414 ARG A NH1 1 
ATOM   3289 N  NH2 . ARG A 1 415 ? 157.816 172.276 161.136 1.00 67.28  0  414 ARG A NH2 1 
ATOM   3290 N  N   . HIS A 1 416 ? 149.668 168.247 161.059 1.00 67.28  0  415 HIS A N   1 
ATOM   3291 C  CA  . HIS A 1 416 ? 148.404 167.875 160.435 1.00 67.28  0  415 HIS A CA  1 
ATOM   3292 C  C   . HIS A 1 416 ? 147.228 168.556 161.120 1.00 67.28  0  415 HIS A C   1 
ATOM   3293 O  O   . HIS A 1 416 ? 146.294 169.012 160.452 1.00 67.28  0  415 HIS A O   1 
ATOM   3294 C  CB  . HIS A 1 416 ? 148.232 166.357 160.459 1.00 67.28  0  415 HIS A CB  1 
ATOM   3295 C  CG  . HIS A 1 416 ? 147.337 165.836 159.379 1.00 67.28  0  415 HIS A CG  1 
ATOM   3296 N  ND1 . HIS A 1 416 ? 147.803 165.071 158.333 1.00 67.28  0  415 HIS A ND1 1 
ATOM   3297 C  CD2 . HIS A 1 416 ? 146.005 165.971 159.182 1.00 67.28  0  415 HIS A CD2 1 
ATOM   3298 C  CE1 . HIS A 1 416 ? 146.796 164.756 157.538 1.00 67.28  0  415 HIS A CE1 1 
ATOM   3299 N  NE2 . HIS A 1 416 ? 145.694 165.290 158.031 1.00 67.28  0  415 HIS A NE2 1 
ATOM   3300 N  N   . PHE A 1 417 ? 147.253 168.633 162.452 1.00 67.28  0  416 PHE A N   1 
ATOM   3301 C  CA  . PHE A 1 417 ? 146.174 169.306 163.169 1.00 67.28  0  416 PHE A CA  1 
ATOM   3302 C  C   . PHE A 1 417 ? 146.104 170.783 162.793 1.00 67.28  0  416 PHE A C   1 
ATOM   3303 O  O   . PHE A 1 417 ? 145.024 171.314 162.490 1.00 67.28  0  416 PHE A O   1 
ATOM   3304 C  CB  . PHE A 1 417 ? 146.367 169.138 164.675 1.00 67.28  0  416 PHE A CB  1 
ATOM   3305 C  CG  . PHE A 1 417 ? 145.311 169.809 165.500 1.00 67.28  0  416 PHE A CG  1 
ATOM   3306 C  CD1 . PHE A 1 417 ? 143.992 169.401 165.420 1.00 67.28  0  416 PHE A CD1 1 
ATOM   3307 C  CD2 . PHE A 1 417 ? 145.636 170.843 166.359 1.00 67.28  0  416 PHE A CD2 1 
ATOM   3308 C  CE1 . PHE A 1 417 ? 143.018 170.013 166.177 1.00 67.28  0  416 PHE A CE1 1 
ATOM   3309 C  CE2 . PHE A 1 417 ? 144.665 171.459 167.120 1.00 67.28  0  416 PHE A CE2 1 
ATOM   3310 C  CZ  . PHE A 1 417 ? 143.354 171.044 167.029 1.00 67.28  0  416 PHE A CZ  1 
ATOM   3311 N  N   . ILE A 1 418 ? 147.257 171.459 162.788 1.00 67.28  0  417 ILE A N   1 
ATOM   3312 C  CA  . ILE A 1 418 ? 147.286 172.877 162.437 1.00 67.28  0  417 ILE A CA  1 
ATOM   3313 C  C   . ILE A 1 418 ? 146.812 173.080 161.004 1.00 67.28  0  417 ILE A C   1 
ATOM   3314 O  O   . ILE A 1 418 ? 146.098 174.043 160.702 1.00 67.28  0  417 ILE A O   1 
ATOM   3315 C  CB  . ILE A 1 418 ? 148.694 173.465 162.653 1.00 67.28  0  417 ILE A CB  1 
ATOM   3316 C  CG1 . ILE A 1 418 ? 149.189 173.202 164.074 1.00 67.28  0  417 ILE A CG1 1 
ATOM   3317 C  CG2 . ILE A 1 418 ? 148.683 174.959 162.393 1.00 67.28  0  417 ILE A CG2 1 
ATOM   3318 C  CD1 . ILE A 1 418 ? 148.484 174.005 165.130 1.00 67.28  0  417 ILE A CD1 1 
ATOM   3319 N  N   . ALA A 1 419 ? 147.201 172.180 160.098 1.00 67.28  0  418 ALA A N   1 
ATOM   3320 C  CA  . ALA A 1 419 ? 146.752 172.288 158.715 1.00 67.28  0  418 ALA A CA  1 
ATOM   3321 C  C   . ALA A 1 419 ? 145.246 172.087 158.603 1.00 67.28  0  418 ALA A C   1 
ATOM   3322 O  O   . ALA A 1 419 ? 144.582 172.759 157.804 1.00 67.28  0  418 ALA A O   1 
ATOM   3323 C  CB  . ALA A 1 419 ? 147.494 171.279 157.841 1.00 67.28  0  418 ALA A CB  1 
ATOM   3324 N  N   . THR A 1 420 ? 144.690 171.157 159.384 1.00 67.28  0  419 THR A N   1 
ATOM   3325 C  CA  . THR A 1 420 ? 143.247 170.942 159.357 1.00 67.28  0  419 THR A CA  1 
ATOM   3326 C  C   . THR A 1 420 ? 142.504 172.189 159.814 1.00 67.28  0  419 THR A C   1 
ATOM   3327 O  O   . THR A 1 420 ? 141.538 172.619 159.174 1.00 67.28  0  419 THR A O   1 
ATOM   3328 C  CB  . THR A 1 420 ? 142.865 169.746 160.230 1.00 67.28  0  419 THR A CB  1 
ATOM   3329 O  OG1 . THR A 1 420 ? 143.504 169.857 161.507 1.00 67.28  0  419 THR A OG1 1 
ATOM   3330 C  CG2 . THR A 1 420 ? 143.281 168.443 159.567 1.00 67.28  0  419 THR A CG2 1 
ATOM   3331 N  N   . VAL A 1 421 ? 142.939 172.788 160.919 1.00 67.28  0  420 VAL A N   1 
ATOM   3332 C  CA  . VAL A 1 421 ? 142.354 174.065 161.372 1.00 67.28  0  420 VAL A CA  1 
ATOM   3333 C  C   . VAL A 1 421 ? 143.208 175.175 160.764 1.00 67.28  0  420 VAL A C   1 
ATOM   3334 O  O   . VAL A 1 421 ? 144.081 175.773 161.397 1.00 67.28  0  420 VAL A O   1 
ATOM   3335 C  CB  . VAL A 1 421 ? 142.226 174.136 162.900 1.00 67.28  0  420 VAL A CB  1 
ATOM   3336 C  CG1 . VAL A 1 421 ? 141.283 173.049 163.382 1.00 67.28  0  420 VAL A CG1 1 
ATOM   3337 C  CG2 . VAL A 1 421 ? 143.569 173.920 163.577 1.00 67.28  0  420 VAL A CG2 1 
ATOM   3338 N  N   . SER A 1 422 ? 142.920 175.485 159.504 1.00 67.28  0  421 SER A N   1 
ATOM   3339 C  CA  . SER A 1 422 ? 143.674 176.482 158.750 1.00 67.28  0  421 SER A CA  1 
ATOM   3340 C  C   . SER A 1 422 ? 142.846 176.898 157.538 1.00 67.28  0  421 SER A C   1 
ATOM   3341 O  O   . SER A 1 422 ? 141.649 176.605 157.452 1.00 67.28  0  421 SER A O   1 
ATOM   3342 C  CB  . SER A 1 422 ? 145.049 175.942 158.343 1.00 67.28  0  421 SER A CB  1 
ATOM   3343 O  OG  . SER A 1 422 ? 145.943 175.946 159.442 1.00 67.28  0  421 SER A OG  1 
ATOM   3344 N  N   . HIS A 1 423 ? 143.486 177.593 156.602 1.00 67.28  0  422 HIS A N   1 
ATOM   3345 C  CA  . HIS A 1 423 ? 142.846 178.056 155.381 1.00 67.28  0  422 HIS A CA  1 
ATOM   3346 C  C   . HIS A 1 423 ? 143.408 177.315 154.175 1.00 67.28  0  422 HIS A C   1 
ATOM   3347 O  O   . HIS A 1 423 ? 144.554 176.857 154.184 1.00 67.28  0  422 HIS A O   1 
ATOM   3348 C  CB  . HIS A 1 423 ? 143.039 179.564 155.194 1.00 67.28  0  422 HIS A CB  1 
ATOM   3349 C  CG  . HIS A 1 423 ? 142.182 180.401 156.091 1.00 67.28  0  422 HIS A CG  1 
ATOM   3350 N  ND1 . HIS A 1 423 ? 142.686 181.084 157.177 1.00 67.28  0  422 HIS A ND1 1 
ATOM   3351 C  CD2 . HIS A 1 423 ? 140.856 180.668 156.061 1.00 67.28  0  422 HIS A CD2 1 
ATOM   3352 C  CE1 . HIS A 1 423 ? 141.706 181.735 157.778 1.00 67.28  0  422 HIS A CE1 1 
ATOM   3353 N  NE2 . HIS A 1 423 ? 140.585 181.499 157.121 1.00 67.28  0  422 HIS A NE2 1 
ATOM   3354 N  N   . ASP A 1 424 ? 142.584 177.197 153.138 1.00 67.28  0  423 ASP A N   1 
ATOM   3355 C  CA  . ASP A 1 424 ? 143.005 176.545 151.908 1.00 67.28  0  423 ASP A CA  1 
ATOM   3356 C  C   . ASP A 1 424 ? 144.099 177.350 151.215 1.00 67.28  0  423 ASP A C   1 
ATOM   3357 O  O   . ASP A 1 424 ? 144.117 178.583 151.256 1.00 67.28  0  423 ASP A O   1 
ATOM   3358 C  CB  . ASP A 1 424 ? 141.818 176.372 150.960 1.00 67.28  0  423 ASP A CB  1 
ATOM   3359 C  CG  . ASP A 1 424 ? 140.886 175.256 151.385 1.00 67.28  0  423 ASP A CG  1 
ATOM   3360 O  OD1 . ASP A 1 424 ? 141.372 174.258 151.954 1.00 67.28  0  423 ASP A OD1 1 
ATOM   3361 O  OD2 . ASP A 1 424 ? 139.666 175.376 151.149 1.00 67.28  -1 423 ASP A OD2 1 
ATOM   3362 N  N   . CYS A 1 425 ? 145.020 176.636 150.573 1.00 67.28  0  424 CYS A N   1 
ATOM   3363 C  CA  . CYS A 1 425 ? 146.054 177.279 149.775 1.00 67.28  0  424 CYS A CA  1 
ATOM   3364 C  C   . CYS A 1 425 ? 145.452 177.769 148.465 1.00 67.28  0  424 CYS A C   1 
ATOM   3365 O  O   . CYS A 1 425 ? 144.786 177.008 147.757 1.00 67.28  0  424 CYS A O   1 
ATOM   3366 C  CB  . CYS A 1 425 ? 147.204 176.312 149.502 1.00 67.28  0  424 CYS A CB  1 
ATOM   3367 S  SG  . CYS A 1 425 ? 148.605 177.047 148.629 1.00 67.28  0  424 CYS A SG  1 
ATOM   3368 N  N   . LYS A 1 426 ? 145.688 179.036 148.142 1.00 67.28  0  425 LYS A N   1 
ATOM   3369 C  CA  . LYS A 1 426 ? 145.117 179.662 146.958 1.00 67.28  0  425 LYS A CA  1 
ATOM   3370 C  C   . LYS A 1 426 ? 146.220 179.976 145.958 1.00 67.28  0  425 LYS A C   1 
ATOM   3371 O  O   . LYS A 1 426 ? 147.215 180.625 146.301 1.00 67.28  0  425 LYS A O   1 
ATOM   3372 C  CB  . LYS A 1 426 ? 144.352 180.934 147.326 1.00 67.28  0  425 LYS A CB  1 
ATOM   3373 C  CG  . LYS A 1 426 ? 142.904 180.688 147.719 1.00 67.28  0  425 LYS A CG  1 
ATOM   3374 C  CD  . LYS A 1 426 ? 142.408 181.735 148.700 1.00 67.28  0  425 LYS A CD  1 
ATOM   3375 C  CE  . LYS A 1 426 ? 142.402 183.118 148.071 1.00 67.28  0  425 LYS A CE  1 
ATOM   3376 N  NZ  . LYS A 1 426 ? 141.828 183.097 146.697 1.00 67.28  1  425 LYS A NZ  1 
ATOM   3377 N  N   . TYR A 1 427 ? 146.041 179.514 144.725 1.00 67.28  0  426 TYR A N   1 
ATOM   3378 C  CA  . TYR A 1 427 ? 146.993 179.770 143.659 1.00 67.28  0  426 TYR A CA  1 
ATOM   3379 C  C   . TYR A 1 427 ? 146.239 180.027 142.364 1.00 67.28  0  426 TYR A C   1 
ATOM   3380 O  O   . TYR A 1 427 ? 145.140 179.508 142.152 1.00 67.28  0  426 TYR A O   1 
ATOM   3381 C  CB  . TYR A 1 427 ? 147.968 178.599 143.475 1.00 67.28  0  426 TYR A CB  1 
ATOM   3382 C  CG  . TYR A 1 427 ? 147.310 177.301 143.062 1.00 67.28  0  426 TYR A CG  1 
ATOM   3383 C  CD1 . TYR A 1 427 ? 146.748 176.454 144.005 1.00 67.28  0  426 TYR A CD1 1 
ATOM   3384 C  CD2 . TYR A 1 427 ? 147.260 176.920 141.729 1.00 67.28  0  426 TYR A CD2 1 
ATOM   3385 C  CE1 . TYR A 1 427 ? 146.150 175.267 143.632 1.00 67.28  0  426 TYR A CE1 1 
ATOM   3386 C  CE2 . TYR A 1 427 ? 146.664 175.736 141.346 1.00 67.28  0  426 TYR A CE2 1 
ATOM   3387 C  CZ  . TYR A 1 427 ? 146.111 174.913 142.301 1.00 67.28  0  426 TYR A CZ  1 
ATOM   3388 O  OH  . TYR A 1 427 ? 145.517 173.732 141.924 1.00 67.28  0  426 TYR A OH  1 
ATOM   3389 N  N   . LEU A 1 428 ? 146.844 180.834 141.501 1.00 67.28  0  427 LEU A N   1 
ATOM   3390 C  CA  . LEU A 1 428 ? 146.324 181.079 140.165 1.00 67.28  0  427 LEU A CA  1 
ATOM   3391 C  C   . LEU A 1 428 ? 147.058 180.177 139.183 1.00 67.28  0  427 LEU A C   1 
ATOM   3392 O  O   . LEU A 1 428 ? 148.289 180.058 139.239 1.00 67.28  0  427 LEU A O   1 
ATOM   3393 C  CB  . LEU A 1 428 ? 146.460 182.555 139.774 1.00 67.28  0  427 LEU A CB  1 
ATOM   3394 C  CG  . LEU A 1 428 ? 147.811 183.275 139.670 1.00 67.28  0  427 LEU A CG  1 
ATOM   3395 C  CD1 . LEU A 1 428 ? 148.496 183.047 138.327 1.00 67.28  0  427 LEU A CD1 1 
ATOM   3396 C  CD2 . LEU A 1 428 ? 147.634 184.763 139.927 1.00 67.28  0  427 LEU A CD2 1 
ATOM   3397 N  N   . GLN A 1 429 ? 146.297 179.519 138.314 1.00 67.28  0  428 GLN A N   1 
ATOM   3398 C  CA  . GLN A 1 429 ? 146.836 178.619 137.302 1.00 67.28  0  428 GLN A CA  1 
ATOM   3399 C  C   . GLN A 1 429 ? 146.742 179.319 135.954 1.00 67.28  0  428 GLN A C   1 
ATOM   3400 O  O   . GLN A 1 429 ? 145.645 179.485 135.409 1.00 67.28  0  428 GLN A O   1 
ATOM   3401 C  CB  . GLN A 1 429 ? 146.080 177.293 137.291 1.00 67.28  0  428 GLN A CB  1 
ATOM   3402 C  CG  . GLN A 1 429 ? 146.530 176.332 136.207 1.00 67.28  0  428 GLN A CG  1 
ATOM   3403 C  CD  . GLN A 1 429 ? 146.148 174.897 136.510 1.00 67.28  0  428 GLN A CD  1 
ATOM   3404 O  OE1 . GLN A 1 429 ? 146.909 174.159 137.135 1.00 67.28  0  428 GLN A OE1 1 
ATOM   3405 N  NE2 . GLN A 1 429 ? 144.963 174.494 136.067 1.00 67.28  0  428 GLN A NE2 1 
ATOM   3406 N  N   . SER A 1 430 ? 147.887 179.726 135.421 1.00 67.28  0  429 SER A N   1 
ATOM   3407 C  CA  . SER A 1 430 ? 147.957 180.413 134.140 1.00 67.28  0  429 SER A CA  1 
ATOM   3408 C  C   . SER A 1 430 ? 148.270 179.394 133.054 1.00 67.28  0  429 SER A C   1 
ATOM   3409 O  O   . SER A 1 430 ? 149.293 178.703 133.122 1.00 67.28  0  429 SER A O   1 
ATOM   3410 C  CB  . SER A 1 430 ? 149.016 181.515 134.168 1.00 67.28  0  429 SER A CB  1 
ATOM   3411 O  OG  . SER A 1 430 ? 148.684 182.518 135.111 1.00 67.28  0  429 SER A OG  1 
ATOM   3412 N  N   . THR A 1 431 ? 147.391 179.302 132.061 1.00 67.28  0  430 THR A N   1 
ATOM   3413 C  CA  . THR A 1 431 ? 147.552 178.386 130.942 1.00 67.28  0  430 THR A CA  1 
ATOM   3414 C  C   . THR A 1 431 ? 147.540 179.179 129.645 1.00 67.28  0  430 THR A C   1 
ATOM   3415 O  O   . THR A 1 431 ? 146.606 179.945 129.389 1.00 67.28  0  430 THR A O   1 
ATOM   3416 C  CB  . THR A 1 431 ? 146.443 177.330 130.925 1.00 67.28  0  430 THR A CB  1 
ATOM   3417 O  OG1 . THR A 1 431 ? 146.324 176.739 132.225 1.00 67.28  0  430 THR A OG1 1 
ATOM   3418 C  CG2 . THR A 1 431 ? 146.755 176.247 129.905 1.00 67.28  0  430 THR A CG2 1 
ATOM   3419 N  N   . ILE A 1 432 ? 148.576 178.993 128.833 1.00 67.28  0  431 ILE A N   1 
ATOM   3420 C  CA  . ILE A 1 432 ? 148.701 179.653 127.540 1.00 67.28  0  431 ILE A CA  1 
ATOM   3421 C  C   . ILE A 1 432 ? 148.743 178.575 126.468 1.00 67.28  0  431 ILE A C   1 
ATOM   3422 O  O   . ILE A 1 432 ? 149.567 177.654 126.539 1.00 67.28  0  431 ILE A O   1 
ATOM   3423 C  CB  . ILE A 1 432 ? 149.946 180.551 127.469 1.00 67.28  0  431 ILE A CB  1 
ATOM   3424 C  CG1 . ILE A 1 432 ? 149.942 181.564 128.614 1.00 67.28  0  431 ILE A CG1 1 
ATOM   3425 C  CG2 . ILE A 1 432 ? 150.011 181.267 126.137 1.00 67.28  0  431 ILE A CG2 1 
ATOM   3426 C  CD1 . ILE A 1 432 ? 151.201 182.398 128.690 1.00 67.28  0  431 ILE A CD1 1 
ATOM   3427 N  N   . SER A 1 433 ? 147.858 178.688 125.482 1.00 67.28  0  432 SER A N   1 
ATOM   3428 C  CA  . SER A 1 433 ? 147.758 177.732 124.388 1.00 67.28  0  432 SER A CA  1 
ATOM   3429 C  C   . SER A 1 433 ? 148.317 178.355 123.116 1.00 67.28  0  432 SER A C   1 
ATOM   3430 O  O   . SER A 1 433 ? 147.971 179.489 122.769 1.00 67.28  0  432 SER A O   1 
ATOM   3431 C  CB  . SER A 1 433 ? 146.308 177.297 124.173 1.00 67.28  0  432 SER A CB  1 
ATOM   3432 O  OG  . SER A 1 433 ? 145.741 176.798 125.372 1.00 67.28  0  432 SER A OG  1 
ATOM   3433 N  N   . PHE A 1 434 ? 149.174 177.610 122.426 1.00 67.28  0  433 PHE A N   1 
ATOM   3434 C  CA  . PHE A 1 434 ? 149.825 178.070 121.210 1.00 67.28  0  433 PHE A CA  1 
ATOM   3435 C  C   . PHE A 1 434 ? 149.433 177.174 120.045 1.00 67.28  0  433 PHE A C   1 
ATOM   3436 O  O   . PHE A 1 434 ? 149.184 175.982 120.219 1.00 67.28  0  433 PHE A O   1 
ATOM   3437 C  CB  . PHE A 1 434 ? 151.349 178.067 121.361 1.00 67.28  0  433 PHE A CB  1 
ATOM   3438 C  CG  . PHE A 1 434 ? 151.881 179.206 122.175 1.00 67.28  0  433 PHE A CG  1 
ATOM   3439 C  CD1 . PHE A 1 434 ? 152.027 180.462 121.615 1.00 67.28  0  433 PHE A CD1 1 
ATOM   3440 C  CD2 . PHE A 1 434 ? 152.233 179.023 123.500 1.00 67.28  0  433 PHE A CD2 1 
ATOM   3441 C  CE1 . PHE A 1 434 ? 152.515 181.512 122.360 1.00 67.28  0  433 PHE A CE1 1 
ATOM   3442 C  CE2 . PHE A 1 434 ? 152.724 180.070 124.249 1.00 67.28  0  433 PHE A CE2 1 
ATOM   3443 C  CZ  . PHE A 1 434 ? 152.864 181.316 123.679 1.00 67.28  0  433 PHE A CZ  1 
ATOM   3444 N  N   . ARG A 1 435 ? 149.391 177.755 118.855 1.00 67.28  0  434 ARG A N   1 
ATOM   3445 C  CA  . ARG A 1 435 ? 149.177 177.023 117.616 1.00 67.28  0  434 ARG A CA  1 
ATOM   3446 C  C   . ARG A 1 435 ? 150.453 177.098 116.792 1.00 67.28  0  434 ARG A C   1 
ATOM   3447 O  O   . ARG A 1 435 ? 150.925 178.197 116.474 1.00 67.28  0  434 ARG A O   1 
ATOM   3448 C  CB  . ARG A 1 435 ? 148.000 177.596 116.832 1.00 67.28  0  434 ARG A CB  1 
ATOM   3449 C  CG  . ARG A 1 435 ? 147.660 176.827 115.564 1.00 67.28  0  434 ARG A CG  1 
ATOM   3450 C  CD  . ARG A 1 435 ? 146.185 176.928 115.206 1.00 67.28  0  434 ARG A CD  1 
ATOM   3451 N  NE  . ARG A 1 435 ? 145.330 176.204 116.139 1.00 67.28  0  434 ARG A NE  1 
ATOM   3452 C  CZ  . ARG A 1 435 ? 145.140 174.891 116.116 1.00 67.28  0  434 ARG A CZ  1 
ATOM   3453 N  NH1 . ARG A 1 435 ? 145.733 174.122 115.218 1.00 67.28  1  434 ARG A NH1 1 
ATOM   3454 N  NH2 . ARG A 1 435 ? 144.333 174.337 117.015 1.00 67.28  0  434 ARG A NH2 1 
ATOM   3455 N  N   . ILE A 1 436 ? 151.014 175.936 116.472 1.00 67.28  0  435 ILE A N   1 
ATOM   3456 C  CA  . ILE A 1 436 ? 152.133 175.810 115.552 1.00 67.28  0  435 ILE A CA  1 
ATOM   3457 C  C   . ILE A 1 436 ? 151.662 174.906 114.423 1.00 67.28  0  435 ILE A C   1 
ATOM   3458 O  O   . ILE A 1 436 ? 151.351 173.729 114.653 1.00 67.28  0  435 ILE A O   1 
ATOM   3459 C  CB  . ILE A 1 436 ? 153.380 175.236 116.237 1.00 67.28  0  435 ILE A CB  1 
ATOM   3460 C  CG1 . ILE A 1 436 ? 153.771 176.090 117.445 1.00 67.28  0  435 ILE A CG1 1 
ATOM   3461 C  CG2 . ILE A 1 436 ? 154.537 175.170 115.259 1.00 67.28  0  435 ILE A CG2 1 
ATOM   3462 C  CD1 . ILE A 1 436 ? 154.879 175.489 118.291 1.00 67.28  0  435 ILE A CD1 1 
ATOM   3463 N  N   . GLY A 1 437 ? 151.593 175.455 113.211 1.00 67.28  0  436 GLY A N   1 
ATOM   3464 C  CA  . GLY A 1 437 ? 151.038 174.745 112.088 1.00 67.28  0  436 GLY A CA  1 
ATOM   3465 C  C   . GLY A 1 437 ? 149.616 174.307 112.371 1.00 67.28  0  436 GLY A C   1 
ATOM   3466 O  O   . GLY A 1 437 ? 148.793 175.082 112.863 1.00 67.28  0  436 GLY A O   1 
ATOM   3467 N  N   . PRO A 1 438 ? 149.295 173.047 112.067 1.00 67.28  0  437 PRO A N   1 
ATOM   3468 C  CA  . PRO A 1 438 ? 147.976 172.516 112.439 1.00 67.28  0  437 PRO A CA  1 
ATOM   3469 C  C   . PRO A 1 438 ? 147.894 172.027 113.875 1.00 67.28  0  437 PRO A C   1 
ATOM   3470 O  O   . PRO A 1 438 ? 146.790 171.705 114.332 1.00 67.28  0  437 PRO A O   1 
ATOM   3471 C  CB  . PRO A 1 438 ? 147.769 171.352 111.458 1.00 67.28  0  437 PRO A CB  1 
ATOM   3472 C  CG  . PRO A 1 438 ? 149.047 171.129 110.763 1.00 67.28  0  437 PRO A CG  1 
ATOM   3473 C  CD  . PRO A 1 438 ? 150.006 172.214 111.086 1.00 67.28  0  437 PRO A CD  1 
ATOM   3474 N  N   . GLU A 1 439 ? 149.005 171.976 114.602 1.00 67.28  0  438 GLU A N   1 
ATOM   3475 C  CA  . GLU A 1 439 ? 149.001 171.446 115.956 1.00 67.28  0  438 GLU A CA  1 
ATOM   3476 C  C   . GLU A 1 439 ? 148.872 172.567 116.983 1.00 67.28  0  438 GLU A C   1 
ATOM   3477 O  O   . GLU A 1 439 ? 149.145 173.736 116.704 1.00 67.28  0  438 GLU A O   1 
ATOM   3478 C  CB  . GLU A 1 439 ? 150.272 170.635 116.221 1.00 67.28  0  438 GLU A CB  1 
ATOM   3479 C  CG  . GLU A 1 439 ? 150.233 169.211 115.688 1.00 67.28  0  438 GLU A CG  1 
ATOM   3480 C  CD  . GLU A 1 439 ? 149.131 168.376 116.321 1.00 67.28  0  438 GLU A CD  1 
ATOM   3481 O  OE1 . GLU A 1 439 ? 148.909 168.504 117.544 1.00 67.28  0  438 GLU A OE1 1 
ATOM   3482 O  OE2 . GLU A 1 439 ? 148.490 167.589 115.595 1.00 67.28  -1 438 GLU A OE2 1 
ATOM   3483 N  N   . LEU A 1 440 ? 148.433 172.197 118.185 1.00 67.28  0  439 LEU A N   1 
ATOM   3484 C  CA  . LEU A 1 440 ? 148.250 173.158 119.266 1.00 67.28  0  439 LEU A CA  1 
ATOM   3485 C  C   . LEU A 1 440 ? 148.906 172.612 120.525 1.00 67.28  0  439 LEU A C   1 
ATOM   3486 O  O   . LEU A 1 440 ? 148.514 171.553 121.024 1.00 67.28  0  439 LEU A O   1 
ATOM   3487 C  CB  . LEU A 1 440 ? 146.763 173.452 119.504 1.00 67.28  0  439 LEU A CB  1 
ATOM   3488 C  CG  . LEU A 1 440 ? 146.371 174.578 120.475 1.00 67.28  0  439 LEU A CG  1 
ATOM   3489 C  CD1 . LEU A 1 440 ? 145.014 175.146 120.109 1.00 67.28  0  439 LEU A CD1 1 
ATOM   3490 C  CD2 . LEU A 1 440 ? 146.362 174.156 121.925 1.00 67.28  0  439 LEU A CD2 1 
ATOM   3491 N  N   . PHE A 1 441 ? 149.885 173.345 121.039 1.00 67.28  0  440 PHE A N   1 
ATOM   3492 C  CA  . PHE A 1 441 ? 150.572 173.020 122.280 1.00 67.28  0  440 PHE A CA  1 
ATOM   3493 C  C   . PHE A 1 441 ? 150.040 173.898 123.412 1.00 67.28  0  440 PHE A C   1 
ATOM   3494 O  O   . PHE A 1 441 ? 149.267 174.833 123.195 1.00 67.28  0  440 PHE A O   1 
ATOM   3495 C  CB  . PHE A 1 441 ? 152.083 173.215 122.120 1.00 67.28  0  440 PHE A CB  1 
ATOM   3496 C  CG  . PHE A 1 441 ? 152.693 172.396 121.016 1.00 67.28  0  440 PHE A CG  1 
ATOM   3497 C  CD1 . PHE A 1 441 ? 152.765 172.902 119.730 1.00 67.28  0  440 PHE A CD1 1 
ATOM   3498 C  CD2 . PHE A 1 441 ? 153.204 171.133 121.261 1.00 67.28  0  440 PHE A CD2 1 
ATOM   3499 C  CE1 . PHE A 1 441 ? 153.328 172.167 118.710 1.00 67.28  0  440 PHE A CE1 1 
ATOM   3500 C  CE2 . PHE A 1 441 ? 153.769 170.391 120.239 1.00 67.28  0  440 PHE A CE2 1 
ATOM   3501 C  CZ  . PHE A 1 441 ? 153.830 170.910 118.964 1.00 67.28  0  440 PHE A CZ  1 
ATOM   3502 N  N   . THR A 1 442 ? 150.475 173.600 124.636 1.00 67.28  0  441 THR A N   1 
ATOM   3503 C  CA  . THR A 1 442 ? 150.058 174.376 125.795 1.00 67.28  0  441 THR A CA  1 
ATOM   3504 C  C   . THR A 1 442 ? 151.237 174.569 126.738 1.00 67.28  0  441 THR A C   1 
ATOM   3505 O  O   . THR A 1 442 ? 152.305 173.977 126.566 1.00 67.28  0  441 THR A O   1 
ATOM   3506 C  CB  . THR A 1 442 ? 148.888 173.711 126.533 1.00 67.28  0  441 THR A CB  1 
ATOM   3507 O  OG1 . THR A 1 442 ? 148.521 174.509 127.665 1.00 67.28  0  441 THR A OG1 1 
ATOM   3508 C  CG2 . THR A 1 442 ? 149.268 172.317 127.000 1.00 67.28  0  441 THR A CG2 1 
ATOM   3509 N  N   . CYS A 1 443 ? 151.044 175.446 127.722 1.00 67.28  0  442 CYS A N   1 
ATOM   3510 C  CA  . CYS A 1 443 ? 152.006 175.628 128.799 1.00 67.28  0  442 CYS A CA  1 
ATOM   3511 C  C   . CYS A 1 443 ? 151.266 176.144 130.024 1.00 67.28  0  442 CYS A C   1 
ATOM   3512 O  O   . CYS A 1 443 ? 150.414 177.030 129.914 1.00 67.28  0  442 CYS A O   1 
ATOM   3513 C  CB  . CYS A 1 443 ? 153.131 176.591 128.406 1.00 67.28  0  442 CYS A CB  1 
ATOM   3514 S  SG  . CYS A 1 443 ? 152.583 178.223 127.875 1.00 67.28  0  442 CYS A SG  1 
ATOM   3515 N  N   . SER A 1 444 ? 151.596 175.589 131.189 1.00 67.28  0  443 SER A N   1 
ATOM   3516 C  CA  . SER A 1 444 ? 150.870 175.878 132.416 1.00 67.28  0  443 SER A CA  1 
ATOM   3517 C  C   . SER A 1 444 ? 151.835 176.258 133.530 1.00 67.28  0  443 SER A C   1 
ATOM   3518 O  O   . SER A 1 444 ? 152.972 175.783 133.584 1.00 67.28  0  443 SER A O   1 
ATOM   3519 C  CB  . SER A 1 444 ? 150.021 174.678 132.859 1.00 67.28  0  443 SER A CB  1 
ATOM   3520 O  OG  . SER A 1 444 ? 150.842 173.582 133.224 1.00 67.28  0  443 SER A OG  1 
ATOM   3521 N  N   . GLY A 1 445 ? 151.360 177.125 134.420 1.00 67.28  0  444 GLY A N   1 
ATOM   3522 C  CA  . GLY A 1 445 ? 152.141 177.531 135.573 1.00 67.28  0  444 GLY A CA  1 
ATOM   3523 C  C   . GLY A 1 445 ? 151.232 177.879 136.730 1.00 67.28  0  444 GLY A C   1 
ATOM   3524 O  O   . GLY A 1 445 ? 150.048 178.179 136.549 1.00 67.28  0  444 GLY A O   1 
ATOM   3525 N  N   . LYS A 1 446 ? 151.802 177.834 137.931 1.00 67.28  0  445 LYS A N   1 
ATOM   3526 C  CA  . LYS A 1 446 ? 151.057 178.078 139.159 1.00 67.28  0  445 LYS A CA  1 
ATOM   3527 C  C   . LYS A 1 446 ? 151.750 179.164 139.964 1.00 67.28  0  445 LYS A C   1 
ATOM   3528 O  O   . LYS A 1 446 ? 152.968 179.109 140.164 1.00 67.28  0  445 LYS A O   1 
ATOM   3529 C  CB  . LYS A 1 446 ? 150.933 176.798 139.991 1.00 67.28  0  445 LYS A CB  1 
ATOM   3530 C  CG  . LYS A 1 446 ? 150.234 175.656 139.273 1.00 67.28  0  445 LYS A CG  1 
ATOM   3531 C  CD  . LYS A 1 446 ? 150.286 174.376 140.087 1.00 67.28  0  445 LYS A CD  1 
ATOM   3532 C  CE  . LYS A 1 446 ? 149.763 173.195 139.289 1.00 67.28  0  445 LYS A CE  1 
ATOM   3533 N  NZ  . LYS A 1 446 ? 149.862 171.922 140.054 1.00 67.28  1  445 LYS A NZ  1 
ATOM   3534 N  N   . THR A 1 447 ? 150.979 180.147 140.423 1.00 67.28  0  446 THR A N   1 
ATOM   3535 C  CA  . THR A 1 447 ? 151.499 181.230 141.251 1.00 67.28  0  446 THR A CA  1 
ATOM   3536 C  C   . THR A 1 447 ? 150.691 181.297 142.539 1.00 67.28  0  446 THR A C   1 
ATOM   3537 O  O   . THR A 1 447 ? 149.467 181.451 142.497 1.00 67.28  0  446 THR A O   1 
ATOM   3538 C  CB  . THR A 1 447 ? 151.441 182.568 140.512 1.00 67.28  0  446 THR A CB  1 
ATOM   3539 O  OG1 . THR A 1 447 ? 151.931 182.399 139.176 1.00 67.28  0  446 THR A OG1 1 
ATOM   3540 C  CG2 . THR A 1 447 ? 152.287 183.608 141.228 1.00 67.28  0  446 THR A CG2 1 
ATOM   3541 N  N   . VAL A 1 448 ? 151.374 181.199 143.675 1.00 67.28  0  447 VAL A N   1 
ATOM   3542 C  CA  . VAL A 1 448 ? 150.705 181.178 144.972 1.00 67.28  0  447 VAL A CA  1 
ATOM   3543 C  C   . VAL A 1 448 ? 150.322 182.598 145.364 1.00 67.28  0  447 VAL A C   1 
ATOM   3544 O  O   . VAL A 1 448 ? 151.171 183.497 145.393 1.00 67.28  0  447 VAL A O   1 
ATOM   3545 C  CB  . VAL A 1 448 ? 151.607 180.537 146.038 1.00 67.28  0  447 VAL A CB  1 
ATOM   3546 C  CG1 . VAL A 1 448 ? 150.876 180.448 147.369 1.00 67.28  0  447 VAL A CG1 1 
ATOM   3547 C  CG2 . VAL A 1 448 ? 152.071 179.165 145.582 1.00 67.28  0  447 VAL A CG2 1 
ATOM   3548 N  N   . LEU A 1 449 ? 149.039 182.808 145.667 1.00 67.28  0  448 LEU A N   1 
ATOM   3549 C  CA  . LEU A 1 449 ? 148.568 184.118 146.096 1.00 67.28  0  448 LEU A CA  1 
ATOM   3550 C  C   . LEU A 1 449 ? 148.567 184.258 147.612 1.00 67.28  0  448 LEU A C   1 
ATOM   3551 O  O   . LEU A 1 449 ? 148.909 185.324 148.135 1.00 67.28  0  448 LEU A O   1 
ATOM   3552 C  CB  . LEU A 1 449 ? 147.162 184.377 145.549 1.00 67.28  0  448 LEU A CB  1 
ATOM   3553 C  CG  . LEU A 1 449 ? 147.041 184.518 144.032 1.00 67.28  0  448 LEU A CG  1 
ATOM   3554 C  CD1 . LEU A 1 449 ? 145.657 185.011 143.648 1.00 67.28  0  448 LEU A CD1 1 
ATOM   3555 C  CD2 . LEU A 1 449 ? 148.112 185.456 143.501 1.00 67.28  0  448 LEU A CD2 1 
ATOM   3556 N  N   . SER A 1 450 ? 148.189 183.203 148.327 1.00 67.28  0  449 SER A N   1 
ATOM   3557 C  CA  . SER A 1 450 ? 148.165 183.225 149.783 1.00 67.28  0  449 SER A CA  1 
ATOM   3558 C  C   . SER A 1 450 ? 148.386 181.821 150.328 1.00 67.28  0  449 SER A C   1 
ATOM   3559 O  O   . SER A 1 450 ? 147.487 180.974 150.244 1.00 67.28  0  449 SER A O   1 
ATOM   3560 C  CB  . SER A 1 450 ? 146.840 183.793 150.293 1.00 67.28  0  449 SER A CB  1 
ATOM   3561 O  OG  . SER A 1 450 ? 145.785 182.865 150.112 1.00 67.28  0  449 SER A OG  1 
ATOM   3562 N  N   . PRO A 1 451 ? 149.560 181.532 150.890 1.00 67.28  0  450 PRO A N   1 
ATOM   3563 C  CA  . PRO A 1 451 ? 149.803 180.199 151.461 1.00 67.28  0  450 PRO A CA  1 
ATOM   3564 C  C   . PRO A 1 451 ? 148.972 179.996 152.720 1.00 67.28  0  450 PRO A C   1 
ATOM   3565 O  O   . PRO A 1 451 ? 149.058 180.777 153.669 1.00 67.28  0  450 PRO A O   1 
ATOM   3566 C  CB  . PRO A 1 451 ? 151.304 180.212 151.767 1.00 67.28  0  450 PRO A CB  1 
ATOM   3567 C  CG  . PRO A 1 451 ? 151.629 181.654 151.964 1.00 67.28  0  450 PRO A CG  1 
ATOM   3568 C  CD  . PRO A 1 451 ? 150.728 182.418 151.031 1.00 67.28  0  450 PRO A CD  1 
ATOM   3569 N  N   . GLY A 1 452 ? 148.163 178.942 152.720 1.00 67.28  0  451 GLY A N   1 
ATOM   3570 C  CA  . GLY A 1 452 ? 147.324 178.637 153.861 1.00 67.28  0  451 GLY A CA  1 
ATOM   3571 C  C   . GLY A 1 452 ? 147.947 177.578 154.743 1.00 67.28  0  451 GLY A C   1 
ATOM   3572 O  O   . GLY A 1 452 ? 148.876 177.866 155.502 1.00 67.28  0  451 GLY A O   1 
ATOM   3573 N  N   . PHE A 1 453 ? 147.443 176.346 154.656 1.00 67.28  0  452 PHE A N   1 
ATOM   3574 C  CA  . PHE A 1 453 ? 148.075 175.248 155.375 1.00 67.28  0  452 PHE A CA  1 
ATOM   3575 C  C   . PHE A 1 453 ? 149.469 174.948 154.842 1.00 67.28  0  452 PHE A C   1 
ATOM   3576 O  O   . PHE A 1 453 ? 150.293 174.389 155.577 1.00 67.28  0  452 PHE A O   1 
ATOM   3577 C  CB  . PHE A 1 453 ? 147.204 173.993 155.309 1.00 67.28  0  452 PHE A CB  1 
ATOM   3578 C  CG  . PHE A 1 453 ? 147.064 173.420 153.929 1.00 67.28  0  452 PHE A CG  1 
ATOM   3579 C  CD1 . PHE A 1 453 ? 146.134 173.931 153.040 1.00 67.28  0  452 PHE A CD1 1 
ATOM   3580 C  CD2 . PHE A 1 453 ? 147.853 172.356 153.525 1.00 67.28  0  452 PHE A CD2 1 
ATOM   3581 C  CE1 . PHE A 1 453 ? 146.004 173.400 151.771 1.00 67.28  0  452 PHE A CE1 1 
ATOM   3582 C  CE2 . PHE A 1 453 ? 147.727 171.821 152.261 1.00 67.28  0  452 PHE A CE2 1 
ATOM   3583 C  CZ  . PHE A 1 453 ? 146.801 172.343 151.382 1.00 67.28  0  452 PHE A CZ  1 
ATOM   3584 N  N   . THR A 1 454 ? 149.773 175.358 153.607 1.00 67.28  0  453 THR A N   1 
ATOM   3585 C  CA  . THR A 1 454 ? 151.086 175.090 153.034 1.00 67.28  0  453 THR A CA  1 
ATOM   3586 C  C   . THR A 1 454 ? 152.091 176.079 153.603 1.00 67.28  0  453 THR A C   1 
ATOM   3587 O  O   . THR A 1 454 ? 152.870 176.703 152.875 1.00 67.28  0  453 THR A O   1 
ATOM   3588 C  CB  . THR A 1 454 ? 151.049 175.181 151.508 1.00 67.28  0  453 THR A CB  1 
ATOM   3589 O  OG1 . THR A 1 454 ? 150.713 176.518 151.116 1.00 67.28  0  453 THR A OG1 1 
ATOM   3590 C  CG2 . THR A 1 454 ? 150.018 174.218 150.942 1.00 67.28  0  453 THR A CG2 1 
ATOM   3591 N  N   . GLU A 1 455 ? 152.055 176.212 154.923 1.00 67.28  0  454 GLU A N   1 
ATOM   3592 C  CA  . GLU A 1 455 ? 153.096 176.828 155.724 1.00 67.28  0  454 GLU A CA  1 
ATOM   3593 C  C   . GLU A 1 455 ? 153.440 175.976 156.930 1.00 67.28  0  454 GLU A C   1 
ATOM   3594 O  O   . GLU A 1 455 ? 154.570 176.063 157.429 1.00 67.28  0  454 GLU A O   1 
ATOM   3595 C  CB  . GLU A 1 455 ? 152.658 178.232 156.177 1.00 67.28  0  454 GLU A CB  1 
ATOM   3596 C  CG  . GLU A 1 455 ? 153.358 178.792 157.405 1.00 67.28  0  454 GLU A CG  1 
ATOM   3597 C  CD  . GLU A 1 455 ? 152.833 180.159 157.800 1.00 67.28  0  454 GLU A CD  1 
ATOM   3598 O  OE1 . GLU A 1 455 ? 151.993 180.709 157.057 1.00 67.28  0  454 GLU A OE1 1 
ATOM   3599 O  OE2 . GLU A 1 455 ? 153.258 180.681 158.851 1.00 67.28  -1 454 GLU A OE2 1 
ATOM   3600 N  N   . VAL A 1 456 ? 152.527 175.112 157.373 1.00 67.28  0  455 VAL A N   1 
ATOM   3601 C  CA  . VAL A 1 456 ? 152.789 174.169 158.450 1.00 67.28  0  455 VAL A CA  1 
ATOM   3602 C  C   . VAL A 1 456 ? 153.162 172.835 157.816 1.00 67.28  0  455 VAL A C   1 
ATOM   3603 O  O   . VAL A 1 456 ? 153.870 172.021 158.418 1.00 67.28  0  455 VAL A O   1 
ATOM   3604 C  CB  . VAL A 1 456 ? 151.571 174.047 159.383 1.00 67.28  0  455 VAL A CB  1 
ATOM   3605 C  CG1 . VAL A 1 456 ? 151.898 173.187 160.587 1.00 67.28  0  455 VAL A CG1 1 
ATOM   3606 C  CG2 . VAL A 1 456 ? 151.111 175.427 159.816 1.00 67.28  0  455 VAL A CG2 1 
ATOM   3607 N  N   . MET A 1 457 ? 152.697 172.610 156.584 1.00 67.28  0  456 MET A N   1 
ATOM   3608 C  CA  . MET A 1 457 ? 153.157 171.499 155.758 1.00 67.28  0  456 MET A CA  1 
ATOM   3609 C  C   . MET A 1 457 ? 153.926 172.016 154.549 1.00 67.28  0  456 MET A C   1 
ATOM   3610 O  O   . MET A 1 457 ? 153.388 172.027 153.433 1.00 67.28  0  456 MET A O   1 
ATOM   3611 C  CB  . MET A 1 457 ? 151.999 170.627 155.272 1.00 67.28  0  456 MET A CB  1 
ATOM   3612 C  CG  . MET A 1 457 ? 151.002 170.179 156.314 1.00 67.28  0  456 MET A CG  1 
ATOM   3613 S  SD  . MET A 1 457 ? 150.465 168.516 155.865 1.00 67.28  0  456 MET A SD  1 
ATOM   3614 C  CE  . MET A 1 457 ? 149.147 168.227 157.029 1.00 67.28  0  456 MET A CE  1 
ATOM   3615 N  N   . PRO A 1 458 ? 155.183 172.434 154.720 1.00 67.28  0  457 PRO A N   1 
ATOM   3616 C  CA  . PRO A 1 458 ? 155.940 172.941 153.565 1.00 67.28  0  457 PRO A CA  1 
ATOM   3617 C  C   . PRO A 1 458 ? 156.077 171.924 152.449 1.00 67.28  0  457 PRO A C   1 
ATOM   3618 O  O   . PRO A 1 458 ? 156.131 172.310 151.274 1.00 67.28  0  457 PRO A O   1 
ATOM   3619 C  CB  . PRO A 1 458 ? 157.306 173.311 154.164 1.00 67.28  0  457 PRO A CB  1 
ATOM   3620 C  CG  . PRO A 1 458 ? 157.114 173.331 155.643 1.00 67.28  0  457 PRO A CG  1 
ATOM   3621 C  CD  . PRO A 1 458 ? 155.981 172.415 155.956 1.00 67.28  0  457 PRO A CD  1 
ATOM   3622 N  N   . TRP A 1 459 ? 156.110 170.630 152.776 1.00 67.28  0  458 TRP A N   1 
ATOM   3623 C  CA  . TRP A 1 459 ? 156.232 169.608 151.746 1.00 67.28  0  458 TRP A CA  1 
ATOM   3624 C  C   . TRP A 1 459 ? 155.002 169.522 150.854 1.00 67.28  0  458 TRP A C   1 
ATOM   3625 O  O   . TRP A 1 459 ? 155.067 168.875 149.803 1.00 67.28  0  458 TRP A O   1 
ATOM   3626 C  CB  . TRP A 1 459 ? 156.514 168.242 152.379 1.00 67.28  0  458 TRP A CB  1 
ATOM   3627 C  CG  . TRP A 1 459 ? 155.385 167.678 153.193 1.00 67.28  0  458 TRP A CG  1 
ATOM   3628 C  CD1 . TRP A 1 459 ? 154.323 166.955 152.733 1.00 67.28  0  458 TRP A CD1 1 
ATOM   3629 C  CD2 . TRP A 1 459 ? 155.220 167.768 154.614 1.00 67.28  0  458 TRP A CD2 1 
ATOM   3630 N  NE1 . TRP A 1 459 ? 153.502 166.601 153.775 1.00 67.28  0  458 TRP A NE1 1 
ATOM   3631 C  CE2 . TRP A 1 459 ? 154.031 167.087 154.941 1.00 67.28  0  458 TRP A CE2 1 
ATOM   3632 C  CE3 . TRP A 1 459 ? 155.960 168.364 155.640 1.00 67.28  0  458 TRP A CE3 1 
ATOM   3633 C  CZ2 . TRP A 1 459 ? 153.566 166.985 156.250 1.00 67.28  0  458 TRP A CZ2 1 
ATOM   3634 C  CZ3 . TRP A 1 459 ? 155.495 168.261 156.939 1.00 67.28  0  458 TRP A CZ3 1 
ATOM   3635 C  CH2 . TRP A 1 459 ? 154.309 167.578 157.232 1.00 67.28  0  458 TRP A CH2 1 
ATOM   3636 N  N   . GLN A 1 460 ? 153.891 170.149 151.239 1.00 67.28  0  459 GLN A N   1 
ATOM   3637 C  CA  . GLN A 1 460 ? 152.718 170.236 150.383 1.00 67.28  0  459 GLN A CA  1 
ATOM   3638 C  C   . GLN A 1 460 ? 152.586 171.598 149.716 1.00 67.28  0  459 GLN A C   1 
ATOM   3639 O  O   . GLN A 1 460 ? 151.541 171.891 149.127 1.00 67.28  0  459 GLN A O   1 
ATOM   3640 C  CB  . GLN A 1 460 ? 151.451 169.917 151.179 1.00 67.28  0  459 GLN A CB  1 
ATOM   3641 C  CG  . GLN A 1 460 ? 151.044 168.455 151.120 1.00 67.28  0  459 GLN A CG  1 
ATOM   3642 C  CD  . GLN A 1 460 ? 149.610 168.230 151.552 1.00 67.28  0  459 GLN A CD  1 
ATOM   3643 O  OE1 . GLN A 1 460 ? 148.711 168.983 151.179 1.00 67.28  0  459 GLN A OE1 1 
ATOM   3644 N  NE2 . GLN A 1 460 ? 149.387 167.187 152.343 1.00 67.28  0  459 GLN A NE2 1 
ATOM   3645 N  N   . SER A 1 461 ? 153.618 172.434 149.796 1.00 67.28  0  460 SER A N   1 
ATOM   3646 C  CA  . SER A 1 461 ? 153.573 173.741 149.161 1.00 67.28  0  460 SER A CA  1 
ATOM   3647 C  C   . SER A 1 461 ? 153.563 173.602 147.643 1.00 67.28  0  460 SER A C   1 
ATOM   3648 O  O   . SER A 1 461 ? 154.139 172.669 147.076 1.00 67.28  0  460 SER A O   1 
ATOM   3649 C  CB  . SER A 1 461 ? 154.766 174.589 149.599 1.00 67.28  0  460 SER A CB  1 
ATOM   3650 O  OG  . SER A 1 461 ? 154.961 175.687 148.725 1.00 67.28  0  460 SER A OG  1 
ATOM   3651 N  N   . VAL A 1 462 ? 152.895 174.543 146.985 1.00 67.28  0  461 VAL A N   1 
ATOM   3652 C  CA  . VAL A 1 462 ? 152.845 174.579 145.526 1.00 67.28  0  461 VAL A CA  1 
ATOM   3653 C  C   . VAL A 1 462 ? 154.227 174.962 145.014 1.00 67.28  0  461 VAL A C   1 
ATOM   3654 O  O   . VAL A 1 462 ? 154.778 175.990 145.436 1.00 67.28  0  461 VAL A O   1 
ATOM   3655 C  CB  . VAL A 1 462 ? 151.770 175.556 145.025 1.00 67.28  0  461 VAL A CB  1 
ATOM   3656 C  CG1 . VAL A 1 462 ? 151.809 175.654 143.508 1.00 67.28  0  461 VAL A CG1 1 
ATOM   3657 C  CG2 . VAL A 1 462 ? 150.395 175.119 145.501 1.00 67.28  0  461 VAL A CG2 1 
ATOM   3658 N  N   . PRO A 1 463 ? 154.829 174.168 144.129 1.00 67.28  0  462 PRO A N   1 
ATOM   3659 C  CA  . PRO A 1 463 ? 156.183 174.482 143.654 1.00 67.28  0  462 PRO A CA  1 
ATOM   3660 C  C   . PRO A 1 463 ? 156.238 175.843 142.976 1.00 67.28  0  462 PRO A C   1 
ATOM   3661 O  O   . PRO A 1 463 ? 155.322 176.236 142.251 1.00 67.28  0  462 PRO A O   1 
ATOM   3662 C  CB  . PRO A 1 463 ? 156.483 173.349 142.666 1.00 67.28  0  462 PRO A CB  1 
ATOM   3663 C  CG  . PRO A 1 463 ? 155.574 172.237 143.078 1.00 67.28  0  462 PRO A CG  1 
ATOM   3664 C  CD  . PRO A 1 463 ? 154.327 172.901 143.572 1.00 67.28  0  462 PRO A CD  1 
ATOM   3665 N  N   . LEU A 1 464 ? 157.329 176.562 143.222 1.00 67.28  0  463 LEU A N   1 
ATOM   3666 C  CA  . LEU A 1 464 ? 157.502 177.892 142.656 1.00 67.28  0  463 LEU A CA  1 
ATOM   3667 C  C   . LEU A 1 464 ? 157.983 177.790 141.215 1.00 67.28  0  463 LEU A C   1 
ATOM   3668 O  O   . LEU A 1 464 ? 158.901 177.023 140.906 1.00 67.28  0  463 LEU A O   1 
ATOM   3669 C  CB  . LEU A 1 464 ? 158.478 178.712 143.505 1.00 67.28  0  463 LEU A CB  1 
ATOM   3670 C  CG  . LEU A 1 464 ? 159.928 178.257 143.702 1.00 67.28  0  463 LEU A CG  1 
ATOM   3671 C  CD1 . LEU A 1 464 ? 160.856 178.818 142.629 1.00 67.28  0  463 LEU A CD1 1 
ATOM   3672 C  CD2 . LEU A 1 464 ? 160.421 178.637 145.090 1.00 67.28  0  463 LEU A CD2 1 
ATOM   3673 N  N   . GLU A 1 465 ? 157.339 178.546 140.328 1.00 68.04  0  464 GLU A N   1 
ATOM   3674 C  CA  . GLU A 1 465 ? 157.724 178.614 138.928 1.00 68.04  0  464 GLU A CA  1 
ATOM   3675 C  C   . GLU A 1 465 ? 157.690 180.067 138.481 1.00 68.04  0  464 GLU A C   1 
ATOM   3676 O  O   . GLU A 1 465 ? 156.908 180.870 138.995 1.00 68.04  0  464 GLU A O   1 
ATOM   3677 C  CB  . GLU A 1 465 ? 156.802 177.773 138.030 1.00 68.04  0  464 GLU A CB  1 
ATOM   3678 C  CG  . GLU A 1 465 ? 156.409 176.421 138.606 1.00 68.04  0  464 GLU A CG  1 
ATOM   3679 C  CD  . GLU A 1 465 ? 155.361 175.715 137.769 1.00 68.04  0  464 GLU A CD  1 
ATOM   3680 O  OE1 . GLU A 1 465 ? 155.058 176.200 136.659 1.00 68.04  0  464 GLU A OE1 1 
ATOM   3681 O  OE2 . GLU A 1 465 ? 154.840 174.674 138.221 1.00 68.04  -1 464 GLU A OE2 1 
ATOM   3682 N  N   . GLU A 1 466 ? 158.550 180.398 137.523 1.00 71.51  0  465 GLU A N   1 
ATOM   3683 C  CA  . GLU A 1 466 ? 158.554 181.743 136.968 1.00 71.51  0  465 GLU A CA  1 
ATOM   3684 C  C   . GLU A 1 466 ? 157.247 182.009 136.232 1.00 71.51  0  465 GLU A C   1 
ATOM   3685 O  O   . GLU A 1 466 ? 156.721 181.138 135.534 1.00 71.51  0  465 GLU A O   1 
ATOM   3686 C  CB  . GLU A 1 466 ? 159.744 181.930 136.027 1.00 71.51  0  465 GLU A CB  1 
ATOM   3687 C  CG  . GLU A 1 466 ? 160.344 183.327 136.065 1.00 71.51  0  465 GLU A CG  1 
ATOM   3688 C  CD  . GLU A 1 466 ? 161.599 183.449 135.224 1.00 71.51  0  465 GLU A CD  1 
ATOM   3689 O  OE1 . GLU A 1 466 ? 162.018 182.434 134.629 1.00 71.51  0  465 GLU A OE1 1 
ATOM   3690 O  OE2 . GLU A 1 466 ? 162.167 184.559 135.159 1.00 71.51  -1 465 GLU A OE2 1 
ATOM   3691 N  N   . SER A 1 467 ? 156.719 183.219 136.401 1.00 71.40  0  466 SER A N   1 
ATOM   3692 C  CA  . SER A 1 467 ? 155.420 183.552 135.834 1.00 71.40  0  466 SER A CA  1 
ATOM   3693 C  C   . SER A 1 467 ? 155.469 183.523 134.312 1.00 71.40  0  466 SER A C   1 
ATOM   3694 O  O   . SER A 1 467 ? 156.447 183.954 133.694 1.00 71.40  0  466 SER A O   1 
ATOM   3695 C  CB  . SER A 1 467 ? 154.969 184.930 136.319 1.00 71.40  0  466 SER A CB  1 
ATOM   3696 O  OG  . SER A 1 467 ? 153.994 185.482 135.451 1.00 71.40  0  466 SER A OG  1 
ATOM   3697 N  N   . LEU A 1 468 ? 154.404 183.003 133.710 1.00 68.18  0  467 LEU A N   1 
ATOM   3698 C  CA  . LEU A 1 468 ? 154.314 182.951 132.262 1.00 68.18  0  467 LEU A CA  1 
ATOM   3699 C  C   . LEU A 1 468 ? 154.166 184.361 131.693 1.00 68.18  0  467 LEU A C   1 
ATOM   3700 O  O   . LEU A 1 468 ? 153.547 185.229 132.315 1.00 68.18  0  467 LEU A O   1 
ATOM   3701 C  CB  . LEU A 1 468 ? 153.135 182.083 131.828 1.00 68.18  0  467 LEU A CB  1 
ATOM   3702 C  CG  . LEU A 1 468 ? 153.306 180.561 131.896 1.00 68.18  0  467 LEU A CG  1 
ATOM   3703 C  CD1 . LEU A 1 468 ? 153.320 180.057 133.329 1.00 68.18  0  467 LEU A CD1 1 
ATOM   3704 C  CD2 . LEU A 1 468 ? 152.215 179.861 131.101 1.00 68.18  0  467 LEU A CD2 1 
ATOM   3705 N  N   . PRO A 1 469 ? 154.739 184.619 130.517 1.00 72.88  0  468 PRO A N   1 
ATOM   3706 C  CA  . PRO A 1 469 ? 154.662 185.967 129.941 1.00 72.88  0  468 PRO A CA  1 
ATOM   3707 C  C   . PRO A 1 469 ? 153.224 186.381 129.668 1.00 72.88  0  468 PRO A C   1 
ATOM   3708 O  O   . PRO A 1 469 ? 152.381 185.564 129.289 1.00 72.88  0  468 PRO A O   1 
ATOM   3709 C  CB  . PRO A 1 469 ? 155.470 185.846 128.643 1.00 72.88  0  468 PRO A CB  1 
ATOM   3710 C  CG  . PRO A 1 469 ? 155.477 184.387 128.333 1.00 72.88  0  468 PRO A CG  1 
ATOM   3711 C  CD  . PRO A 1 469 ? 155.502 183.698 129.661 1.00 72.88  0  468 PRO A CD  1 
ATOM   3712 N  N   . THR A 1 470 ? 152.951 187.668 129.866 1.00 76.99  0  469 THR A N   1 
ATOM   3713 C  CA  . THR A 1 470 ? 151.617 188.229 129.658 1.00 76.99  0  469 THR A CA  1 
ATOM   3714 C  C   . THR A 1 470 ? 151.445 188.508 128.171 1.00 76.99  0  469 THR A C   1 
ATOM   3715 O  O   . THR A 1 470 ? 151.819 189.566 127.664 1.00 76.99  0  469 THR A O   1 
ATOM   3716 C  CB  . THR A 1 470 ? 151.425 189.492 130.487 1.00 76.99  0  469 THR A CB  1 
ATOM   3717 O  OG1 . THR A 1 470 ? 152.533 190.376 130.277 1.00 76.99  0  469 THR A OG1 1 
ATOM   3718 C  CG2 . THR A 1 470 ? 151.333 189.148 131.967 1.00 76.99  0  469 THR A CG2 1 
ATOM   3719 N  N   . CYS A 1 471 ? 150.870 187.541 127.461 1.00 76.11  0  470 CYS A N   1 
ATOM   3720 C  CA  . CYS A 1 471 ? 150.648 187.642 126.024 1.00 76.11  0  470 CYS A CA  1 
ATOM   3721 C  C   . CYS A 1 471 ? 149.152 187.665 125.753 1.00 76.11  0  470 CYS A C   1 
ATOM   3722 O  O   . CYS A 1 471 ? 148.425 186.762 126.181 1.00 76.11  0  470 CYS A O   1 
ATOM   3723 C  CB  . CYS A 1 471 ? 151.313 186.480 125.283 1.00 76.11  0  470 CYS A CB  1 
ATOM   3724 S  SG  . CYS A 1 471 ? 150.981 184.852 125.992 1.00 76.11  0  470 CYS A SG  1 
ATOM   3725 N  N   . GLN A 1 472 ? 148.697 188.697 125.048 1.00 75.85  0  471 GLN A N   1 
ATOM   3726 C  CA  . GLN A 1 472 ? 147.305 188.793 124.644 1.00 75.85  0  471 GLN A CA  1 
ATOM   3727 C  C   . GLN A 1 472 ? 147.031 187.857 123.469 1.00 75.85  0  471 GLN A C   1 
ATOM   3728 O  O   . GLN A 1 472 ? 147.945 187.366 122.805 1.00 75.85  0  471 GLN A O   1 
ATOM   3729 C  CB  . GLN A 1 472 ? 146.954 190.231 124.270 1.00 75.85  0  471 GLN A CB  1 
ATOM   3730 C  CG  . GLN A 1 472 ? 146.993 191.205 125.434 1.00 75.85  0  471 GLN A CG  1 
ATOM   3731 C  CD  . GLN A 1 472 ? 146.659 192.621 125.014 1.00 75.85  0  471 GLN A CD  1 
ATOM   3732 O  OE1 . GLN A 1 472 ? 146.459 192.899 123.832 1.00 75.85  0  471 GLN A OE1 1 
ATOM   3733 N  NE2 . GLN A 1 472 ? 146.596 193.527 125.983 1.00 75.85  0  471 GLN A NE2 1 
ATOM   3734 N  N   . ARG A 1 473 ? 145.747 187.620 123.211 1.00 76.57  0  472 ARG A N   1 
ATOM   3735 C  CA  . ARG A 1 473 ? 145.350 186.753 122.110 1.00 76.57  0  472 ARG A CA  1 
ATOM   3736 C  C   . ARG A 1 473 ? 145.793 187.348 120.777 1.00 76.57  0  472 ARG A C   1 
ATOM   3737 O  O   . ARG A 1 473 ? 145.850 188.568 120.602 1.00 76.57  0  472 ARG A O   1 
ATOM   3738 C  CB  . ARG A 1 473 ? 143.832 186.542 122.124 1.00 76.57  0  472 ARG A CB  1 
ATOM   3739 C  CG  . ARG A 1 473 ? 143.285 185.767 120.931 1.00 76.57  0  472 ARG A CG  1 
ATOM   3740 C  CD  . ARG A 1 473 ? 141.906 185.194 121.209 1.00 76.57  0  472 ARG A CD  1 
ATOM   3741 N  NE  . ARG A 1 473 ? 141.496 184.255 120.172 1.00 76.57  0  472 ARG A NE  1 
ATOM   3742 C  CZ  . ARG A 1 473 ? 140.545 183.344 120.317 1.00 76.57  0  472 ARG A CZ  1 
ATOM   3743 N  NH1 . ARG A 1 473 ? 139.877 183.217 121.452 1.00 76.57  1  472 ARG A NH1 1 
ATOM   3744 N  NH2 . ARG A 1 473 ? 140.256 182.538 119.299 1.00 76.57  0  472 ARG A NH2 1 
ATOM   3745 N  N   . GLY A 1 474 ? 146.107 186.470 119.830 1.00 76.01  0  473 GLY A N   1 
ATOM   3746 C  CA  . GLY A 1 474 ? 146.572 186.901 118.523 1.00 76.01  0  473 GLY A CA  1 
ATOM   3747 C  C   . GLY A 1 474 ? 147.952 187.521 118.520 1.00 76.01  0  473 GLY A C   1 
ATOM   3748 O  O   . GLY A 1 474 ? 148.177 188.523 117.830 1.00 76.01  0  473 GLY A O   1 
ATOM   3749 N  N   . ASP A 1 475 ? 148.883 186.950 119.278 1.00 75.97  0  474 ASP A N   1 
ATOM   3750 C  CA  . ASP A 1 475 ? 150.270 187.386 119.297 1.00 75.97  0  474 ASP A CA  1 
ATOM   3751 C  C   . ASP A 1 475 ? 151.153 186.293 118.709 1.00 75.97  0  474 ASP A C   1 
ATOM   3752 O  O   . ASP A 1 475 ? 150.915 185.103 118.933 1.00 75.97  0  474 ASP A O   1 
ATOM   3753 C  CB  . ASP A 1 475 ? 150.726 187.720 120.720 1.00 75.97  0  474 ASP A CB  1 
ATOM   3754 C  CG  . ASP A 1 475 ? 150.214 189.065 121.195 1.00 75.97  0  474 ASP A CG  1 
ATOM   3755 O  OD1 . ASP A 1 475 ? 149.640 189.809 120.372 1.00 75.97  0  474 ASP A OD1 1 
ATOM   3756 O  OD2 . ASP A 1 475 ? 150.388 189.380 122.391 1.00 75.97  -1 474 ASP A OD2 1 
ATOM   3757 N  N   . ALA A 1 476 ? 152.170 186.703 117.958 1.00 76.98  0  475 ALA A N   1 
ATOM   3758 C  CA  . ALA A 1 476 ? 153.067 185.777 117.281 1.00 76.98  0  475 ALA A CA  1 
ATOM   3759 C  C   . ALA A 1 476 ? 154.401 185.720 118.014 1.00 76.98  0  475 ALA A C   1 
ATOM   3760 O  O   . ALA A 1 476 ? 155.008 186.760 118.290 1.00 76.98  0  475 ALA A O   1 
ATOM   3761 C  CB  . ALA A 1 476 ? 153.282 186.191 115.825 1.00 76.98  0  475 ALA A CB  1 
ATOM   3762 N  N   . PHE A 1 477 ? 154.854 184.505 118.319 1.00 75.74  0  476 PHE A N   1 
ATOM   3763 C  CA  . PHE A 1 477 ? 156.104 184.275 119.017 1.00 75.74  0  476 PHE A CA  1 
ATOM   3764 C  C   . PHE A 1 477 ? 157.039 183.420 118.170 1.00 75.74  0  476 PHE A C   1 
ATOM   3765 O  O   . PHE A 1 477 ? 156.581 182.524 117.450 1.00 75.74  0  476 PHE A O   1 
ATOM   3766 C  CB  . PHE A 1 477 ? 155.868 183.579 120.367 1.00 75.74  0  476 PHE A CB  1 
ATOM   3767 C  CG  . PHE A 1 477 ? 155.347 184.491 121.442 1.00 75.74  0  476 PHE A CG  1 
ATOM   3768 C  CD1 . PHE A 1 477 ? 155.304 185.861 121.251 1.00 75.74  0  476 PHE A CD1 1 
ATOM   3769 C  CD2 . PHE A 1 477 ? 154.903 183.975 122.647 1.00 75.74  0  476 PHE A CD2 1 
ATOM   3770 C  CE1 . PHE A 1 477 ? 154.826 186.698 122.240 1.00 75.74  0  476 PHE A CE1 1 
ATOM   3771 C  CE2 . PHE A 1 477 ? 154.423 184.806 123.639 1.00 75.74  0  476 PHE A CE2 1 
ATOM   3772 C  CZ  . PHE A 1 477 ? 154.385 186.169 123.436 1.00 75.74  0  476 PHE A CZ  1 
ATOM   3773 N  N   . PRO A 1 478 ? 158.344 183.674 118.225 1.00 73.40  0  477 PRO A N   1 
ATOM   3774 C  CA  . PRO A 1 478 ? 159.288 182.820 117.498 1.00 73.40  0  477 PRO A CA  1 
ATOM   3775 C  C   . PRO A 1 478 ? 159.468 181.478 118.191 1.00 73.40  0  477 PRO A C   1 
ATOM   3776 O  O   . PRO A 1 478 ? 159.468 181.386 119.422 1.00 73.40  0  477 PRO A O   1 
ATOM   3777 C  CB  . PRO A 1 478 ? 160.584 183.636 117.509 1.00 73.40  0  477 PRO A CB  1 
ATOM   3778 C  CG  . PRO A 1 478 ? 160.476 184.478 118.734 1.00 73.40  0  477 PRO A CG  1 
ATOM   3779 C  CD  . PRO A 1 478 ? 159.015 184.805 118.889 1.00 73.40  0  477 PRO A CD  1 
ATOM   3780 N  N   . VAL A 1 479 ? 159.622 180.433 117.383 1.00 69.38  0  478 VAL A N   1 
ATOM   3781 C  CA  . VAL A 1 479 ? 159.853 179.077 117.867 1.00 69.38  0  478 VAL A CA  1 
ATOM   3782 C  C   . VAL A 1 479 ? 161.287 178.688 117.531 1.00 69.38  0  478 VAL A C   1 
ATOM   3783 O  O   . VAL A 1 479 ? 161.734 178.854 116.390 1.00 69.38  0  478 VAL A O   1 
ATOM   3784 C  CB  . VAL A 1 479 ? 158.838 178.082 117.273 1.00 69.38  0  478 VAL A CB  1 
ATOM   3785 C  CG1 . VAL A 1 479 ? 158.841 178.135 115.754 1.00 69.38  0  478 VAL A CG1 1 
ATOM   3786 C  CG2 . VAL A 1 479 ? 159.129 176.670 117.757 1.00 69.38  0  478 VAL A CG2 1 
ATOM   3787 N  N   . GLY A 1 480 ? 162.014 178.199 118.532 1.00 69.80  0  479 GLY A N   1 
ATOM   3788 C  CA  . GLY A 1 480 ? 163.402 177.834 118.341 1.00 69.80  0  479 GLY A CA  1 
ATOM   3789 C  C   . GLY A 1 480 ? 163.578 176.490 117.668 1.00 69.80  0  479 GLY A C   1 
ATOM   3790 O  O   . GLY A 1 480 ? 164.221 176.392 116.619 1.00 69.80  0  479 GLY A O   1 
ATOM   3791 N  N   . GLU A 1 481 ? 163.010 175.444 118.262 1.00 67.28  0  480 GLU A N   1 
ATOM   3792 C  CA  . GLU A 1 481 ? 163.150 174.102 117.718 1.00 67.28  0  480 GLU A CA  1 
ATOM   3793 C  C   . GLU A 1 481 ? 161.973 173.250 118.166 1.00 67.28  0  480 GLU A C   1 
ATOM   3794 O  O   . GLU A 1 481 ? 161.431 173.439 119.258 1.00 67.28  0  480 GLU A O   1 
ATOM   3795 C  CB  . GLU A 1 481 ? 164.470 173.457 118.156 1.00 67.28  0  480 GLU A CB  1 
ATOM   3796 C  CG  . GLU A 1 481 ? 164.568 173.200 119.652 1.00 67.28  0  480 GLU A CG  1 
ATOM   3797 C  CD  . GLU A 1 481 ? 165.908 172.622 120.062 1.00 67.28  0  480 GLU A CD  1 
ATOM   3798 O  OE1 . GLU A 1 481 ? 166.775 172.442 119.181 1.00 67.28  0  480 GLU A OE1 1 
ATOM   3799 O  OE2 . GLU A 1 481 ? 166.094 172.347 121.266 1.00 67.28  -1 480 GLU A OE2 1 
ATOM   3800 N  N   . VAL A 1 482 ? 161.581 172.319 117.301 1.00 67.28  0  481 VAL A N   1 
ATOM   3801 C  CA  . VAL A 1 482 ? 160.594 171.296 117.624 1.00 67.28  0  481 VAL A CA  1 
ATOM   3802 C  C   . VAL A 1 482 ? 161.156 169.948 117.192 1.00 67.28  0  481 VAL A C   1 
ATOM   3803 O  O   . VAL A 1 482 ? 161.671 169.812 116.076 1.00 67.28  0  481 VAL A O   1 
ATOM   3804 C  CB  . VAL A 1 482 ? 159.232 171.572 116.958 1.00 67.28  0  481 VAL A CB  1 
ATOM   3805 C  CG1 . VAL A 1 482 ? 158.586 172.803 117.571 1.00 67.28  0  481 VAL A CG1 1 
ATOM   3806 C  CG2 . VAL A 1 482 ? 159.396 171.770 115.465 1.00 67.28  0  481 VAL A CG2 1 
ATOM   3807 N  N   . LYS A 1 483 ? 161.086 168.963 118.083 1.00 67.28  0  482 LYS A N   1 
ATOM   3808 C  CA  . LYS A 1 483 ? 161.663 167.654 117.816 1.00 67.28  0  482 LYS A CA  1 
ATOM   3809 C  C   . LYS A 1 483 ? 160.899 166.594 118.592 1.00 67.28  0  482 LYS A C   1 
ATOM   3810 O  O   . LYS A 1 483 ? 160.431 166.847 119.706 1.00 67.28  0  482 LYS A O   1 
ATOM   3811 C  CB  . LYS A 1 483 ? 163.149 167.620 118.188 1.00 67.28  0  482 LYS A CB  1 
ATOM   3812 C  CG  . LYS A 1 483 ? 163.425 167.895 119.657 1.00 67.28  0  482 LYS A CG  1 
ATOM   3813 C  CD  . LYS A 1 483 ? 164.916 167.934 119.947 1.00 67.28  0  482 LYS A CD  1 
ATOM   3814 C  CE  . LYS A 1 483 ? 165.181 168.082 121.436 1.00 67.28  0  482 LYS A CE  1 
ATOM   3815 N  NZ  . LYS A 1 483 ? 164.660 169.372 121.967 1.00 67.28  1  482 LYS A NZ  1 
ATOM   3816 N  N   . MET A 1 484 ? 160.769 165.412 117.996 1.00 67.28  0  483 MET A N   1 
ATOM   3817 C  CA  . MET A 1 484 ? 160.137 164.305 118.692 1.00 67.28  0  483 MET A CA  1 
ATOM   3818 C  C   . MET A 1 484 ? 161.137 163.618 119.615 1.00 67.28  0  483 MET A C   1 
ATOM   3819 O  O   . MET A 1 484 ? 162.354 163.792 119.501 1.00 67.28  0  483 MET A O   1 
ATOM   3820 C  CB  . MET A 1 484 ? 159.565 163.281 117.710 1.00 67.28  0  483 MET A CB  1 
ATOM   3821 C  CG  . MET A 1 484 ? 160.612 162.578 116.862 1.00 67.28  0  483 MET A CG  1 
ATOM   3822 S  SD  . MET A 1 484 ? 159.899 161.447 115.650 1.00 67.28  0  483 MET A SD  1 
ATOM   3823 C  CE  . MET A 1 484 ? 159.222 162.588 114.451 1.00 67.28  0  483 MET A CE  1 
ATOM   3824 N  N   . LEU A 1 485 ? 160.605 162.823 120.536 1.00 67.28  0  484 LEU A N   1 
ATOM   3825 C  CA  . LEU A 1 485 ? 161.406 162.058 121.476 1.00 67.28  0  484 LEU A CA  1 
ATOM   3826 C  C   . LEU A 1 485 ? 161.087 160.576 121.332 1.00 67.28  0  484 LEU A C   1 
ATOM   3827 O  O   . LEU A 1 485 ? 160.079 160.190 120.735 1.00 67.28  0  484 LEU A O   1 
ATOM   3828 C  CB  . LEU A 1 485 ? 161.162 162.521 122.918 1.00 67.28  0  484 LEU A CB  1 
ATOM   3829 C  CG  . LEU A 1 485 ? 161.488 163.989 123.205 1.00 67.28  0  484 LEU A CG  1 
ATOM   3830 C  CD1 . LEU A 1 485 ? 161.420 164.278 124.694 1.00 67.28  0  484 LEU A CD1 1 
ATOM   3831 C  CD2 . LEU A 1 485 ? 162.857 164.350 122.658 1.00 67.28  0  484 LEU A CD2 1 
ATOM   3832 N  N   . GLU A 1 486 ? 161.962 159.744 121.892 1.00 67.28  0  485 GLU A N   1 
ATOM   3833 C  CA  . GLU A 1 486 ? 161.838 158.299 121.757 1.00 67.28  0  485 GLU A CA  1 
ATOM   3834 C  C   . GLU A 1 486 ? 161.642 157.665 123.128 1.00 67.28  0  485 GLU A C   1 
ATOM   3835 O  O   . GLU A 1 486 ? 162.298 156.674 123.466 1.00 67.28  0  485 GLU A O   1 
ATOM   3836 C  CB  . GLU A 1 486 ? 163.072 157.721 121.058 1.00 67.28  0  485 GLU A CB  1 
ATOM   3837 C  CG  . GLU A 1 486 ? 162.873 156.340 120.446 1.00 67.28  0  485 GLU A CG  1 
ATOM   3838 C  CD  . GLU A 1 486 ? 162.140 156.389 119.121 1.00 67.28  0  485 GLU A CD  1 
ATOM   3839 O  OE1 . GLU A 1 486 ? 162.098 157.474 118.503 1.00 67.28  0  485 GLU A OE1 1 
ATOM   3840 O  OE2 . GLU A 1 486 ? 161.608 155.343 118.695 1.00 67.28  -1 485 GLU A OE2 1 
ATOM   3841 N  N   . LYS A 1 487 ? 160.753 158.243 123.929 1.00 67.28  0  486 LYS A N   1 
ATOM   3842 C  CA  . LYS A 1 487 ? 160.520 157.749 125.277 1.00 67.28  0  486 LYS A CA  1 
ATOM   3843 C  C   . LYS A 1 487 ? 159.930 156.343 125.253 1.00 67.28  0  486 LYS A C   1 
ATOM   3844 O  O   . LYS A 1 487 ? 159.186 155.968 124.344 1.00 67.28  0  486 LYS A O   1 
ATOM   3845 C  CB  . LYS A 1 487 ? 159.586 158.689 126.038 1.00 67.28  0  486 LYS A CB  1 
ATOM   3846 C  CG  . LYS A 1 487 ? 160.227 159.997 126.466 1.00 67.28  0  486 LYS A CG  1 
ATOM   3847 C  CD  . LYS A 1 487 ? 159.292 160.794 127.360 1.00 67.28  0  486 LYS A CD  1 
ATOM   3848 C  CE  . LYS A 1 487 ? 160.066 161.710 128.294 1.00 67.28  0  486 LYS A CE  1 
ATOM   3849 N  NZ  . LYS A 1 487 ? 160.715 162.834 127.571 1.00 67.28  1  486 LYS A NZ  1 
ATOM   3850 N  N   . GLN A 1 488 ? 160.277 155.564 126.272 1.00 67.28  0  487 GLN A N   1 
ATOM   3851 C  CA  . GLN A 1 488 ? 159.773 154.211 126.453 1.00 67.28  0  487 GLN A CA  1 
ATOM   3852 C  C   . GLN A 1 488 ? 159.021 154.133 127.773 1.00 67.28  0  487 GLN A C   1 
ATOM   3853 O  O   . GLN A 1 488 ? 159.444 154.724 128.772 1.00 67.28  0  487 GLN A O   1 
ATOM   3854 C  CB  . GLN A 1 488 ? 160.912 153.188 126.437 1.00 67.28  0  487 GLN A CB  1 
ATOM   3855 C  CG  . GLN A 1 488 ? 161.121 152.510 125.095 1.00 67.28  0  487 GLN A CG  1 
ATOM   3856 C  CD  . GLN A 1 488 ? 162.173 151.422 125.153 1.00 67.28  0  487 GLN A CD  1 
ATOM   3857 O  OE1 . GLN A 1 488 ? 162.617 151.028 126.231 1.00 67.28  0  487 GLN A OE1 1 
ATOM   3858 N  NE2 . GLN A 1 488 ? 162.580 150.930 123.989 1.00 67.28  0  487 GLN A NE2 1 
ATOM   3859 N  N   . THR A 1 489 ? 157.902 153.414 127.774 1.00 67.28  0  488 THR A N   1 
ATOM   3860 C  CA  . THR A 1 489 ? 157.114 153.273 128.990 1.00 67.28  0  488 THR A CA  1 
ATOM   3861 C  C   . THR A 1 489 ? 157.907 152.514 130.047 1.00 67.28  0  488 THR A C   1 
ATOM   3862 O  O   . THR A 1 489 ? 158.680 151.603 129.736 1.00 67.28  0  488 THR A O   1 
ATOM   3863 C  CB  . THR A 1 489 ? 155.792 152.562 128.696 1.00 67.28  0  488 THR A CB  1 
ATOM   3864 O  OG1 . THR A 1 489 ? 155.054 152.395 129.913 1.00 67.28  0  488 THR A OG1 1 
ATOM   3865 C  CG2 . THR A 1 489 ? 156.036 151.203 128.065 1.00 67.28  0  488 THR A CG2 1 
ATOM   3866 N  N   . ASN A 1 490 ? 157.722 152.906 131.310 1.00 67.28  0  489 ASN A N   1 
ATOM   3867 C  CA  . ASN A 1 490 ? 158.549 152.337 132.360 1.00 67.28  0  489 ASN A CA  1 
ATOM   3868 C  C   . ASN A 1 490 ? 157.784 151.279 133.145 1.00 67.28  0  489 ASN A C   1 
ATOM   3869 O  O   . ASN A 1 490 ? 156.567 151.386 133.324 1.00 67.28  0  489 ASN A O   1 
ATOM   3870 C  CB  . ASN A 1 490 ? 159.028 153.431 133.319 1.00 67.28  0  489 ASN A CB  1 
ATOM   3871 C  CG  . ASN A 1 490 ? 160.228 154.187 132.785 1.00 67.28  0  489 ASN A CG  1 
ATOM   3872 O  OD1 . ASN A 1 490 ? 160.984 153.673 131.962 1.00 67.28  0  489 ASN A OD1 1 
ATOM   3873 N  ND2 . ASN A 1 490 ? 160.406 155.419 133.250 1.00 67.28  0  489 ASN A ND2 1 
ATOM   3874 N  N   . PRO A 1 491 ? 158.478 150.242 133.621 1.00 67.28  0  490 PRO A N   1 
ATOM   3875 C  CA  . PRO A 1 491 ? 157.801 149.219 134.410 1.00 67.28  0  490 PRO A CA  1 
ATOM   3876 C  C   . PRO A 1 491 ? 157.382 149.768 135.760 1.00 67.28  0  490 PRO A C   1 
ATOM   3877 O  O   . PRO A 1 491 ? 158.028 150.681 136.303 1.00 67.28  0  490 PRO A O   1 
ATOM   3878 C  CB  . PRO A 1 491 ? 158.869 148.121 134.556 1.00 67.28  0  490 PRO A CB  1 
ATOM   3879 C  CG  . PRO A 1 491 ? 160.159 148.850 134.445 1.00 67.28  0  490 PRO A CG  1 
ATOM   3880 C  CD  . PRO A 1 491 ? 159.916 149.964 133.465 1.00 67.28  0  490 PRO A CD  1 
ATOM   3881 N  N   . PRO A 1 492 ? 156.302 149.251 136.340 1.00 67.28  0  491 PRO A N   1 
ATOM   3882 C  CA  . PRO A 1 492 ? 155.911 149.686 137.683 1.00 67.28  0  491 PRO A CA  1 
ATOM   3883 C  C   . PRO A 1 492 ? 156.951 149.280 138.711 1.00 67.28  0  491 PRO A C   1 
ATOM   3884 O  O   . PRO A 1 492 ? 157.684 148.303 138.538 1.00 67.28  0  491 PRO A O   1 
ATOM   3885 C  CB  . PRO A 1 492 ? 154.580 148.962 137.922 1.00 67.28  0  491 PRO A CB  1 
ATOM   3886 C  CG  . PRO A 1 492 ? 154.108 148.549 136.564 1.00 67.28  0  491 PRO A CG  1 
ATOM   3887 C  CD  . PRO A 1 492 ? 155.350 148.281 135.777 1.00 67.28  0  491 PRO A CD  1 
ATOM   3888 N  N   . ASP A 1 493 ? 157.021 150.053 139.787 1.00 67.28  0  492 ASP A N   1 
ATOM   3889 C  CA  . ASP A 1 493 ? 157.926 149.741 140.879 1.00 67.28  0  492 ASP A CA  1 
ATOM   3890 C  C   . ASP A 1 493 ? 157.260 148.770 141.850 1.00 67.28  0  492 ASP A C   1 
ATOM   3891 O  O   . ASP A 1 493 ? 156.055 148.516 141.790 1.00 67.28  0  492 ASP A O   1 
ATOM   3892 C  CB  . ASP A 1 493 ? 158.358 151.019 141.599 1.00 67.28  0  492 ASP A CB  1 
ATOM   3893 C  CG  . ASP A 1 493 ? 159.829 151.011 141.963 1.00 67.28  0  492 ASP A CG  1 
ATOM   3894 O  OD1 . ASP A 1 493 ? 160.440 149.923 141.945 1.00 67.28  0  492 ASP A OD1 1 
ATOM   3895 O  OD2 . ASP A 1 493 ? 160.376 152.094 142.261 1.00 67.28  -1 492 ASP A OD2 1 
ATOM   3896 N  N   . TYR A 1 494 ? 158.066 148.215 142.750 1.00 67.28  0  493 TYR A N   1 
ATOM   3897 C  CA  . TYR A 1 494 ? 157.541 147.285 143.739 1.00 67.28  0  493 TYR A CA  1 
ATOM   3898 C  C   . TYR A 1 494 ? 156.570 147.994 144.675 1.00 67.28  0  493 TYR A C   1 
ATOM   3899 O  O   . TYR A 1 494 ? 156.671 149.199 144.920 1.00 67.28  0  493 TYR A O   1 
ATOM   3900 C  CB  . TYR A 1 494 ? 158.678 146.649 144.536 1.00 67.28  0  493 TYR A CB  1 
ATOM   3901 C  CG  . TYR A 1 494 ? 159.391 145.543 143.794 1.00 67.28  0  493 TYR A CG  1 
ATOM   3902 C  CD1 . TYR A 1 494 ? 158.731 144.370 143.459 1.00 67.28  0  493 TYR A CD1 1 
ATOM   3903 C  CD2 . TYR A 1 494 ? 160.722 145.672 143.426 1.00 67.28  0  493 TYR A CD2 1 
ATOM   3904 C  CE1 . TYR A 1 494 ? 159.376 143.356 142.780 1.00 67.28  0  493 TYR A CE1 1 
ATOM   3905 C  CE2 . TYR A 1 494 ? 161.376 144.663 142.747 1.00 67.28  0  493 TYR A CE2 1 
ATOM   3906 C  CZ  . TYR A 1 494 ? 160.698 143.507 142.426 1.00 67.28  0  493 TYR A CZ  1 
ATOM   3907 O  OH  . TYR A 1 494 ? 161.344 142.499 141.749 1.00 67.28  0  493 TYR A OH  1 
ATOM   3908 N  N   . LEU A 1 495 ? 155.614 147.227 145.192 1.00 67.28  0  494 LEU A N   1 
ATOM   3909 C  CA  . LEU A 1 495 ? 154.544 147.799 145.996 1.00 67.28  0  494 LEU A CA  1 
ATOM   3910 C  C   . LEU A 1 495 ? 155.102 148.369 147.294 1.00 67.28  0  494 LEU A C   1 
ATOM   3911 O  O   . LEU A 1 495 ? 155.766 147.666 148.061 1.00 67.28  0  494 LEU A O   1 
ATOM   3912 C  CB  . LEU A 1 495 ? 153.492 146.731 146.288 1.00 67.28  0  494 LEU A CB  1 
ATOM   3913 C  CG  . LEU A 1 495 ? 152.149 147.182 146.857 1.00 67.28  0  494 LEU A CG  1 
ATOM   3914 C  CD1 . LEU A 1 495 ? 151.401 148.002 145.823 1.00 67.28  0  494 LEU A CD1 1 
ATOM   3915 C  CD2 . LEU A 1 495 ? 151.325 145.984 147.290 1.00 67.28  0  494 LEU A CD2 1 
ATOM   3916 N  N   . THR A 1 496 ? 154.831 149.649 147.536 1.00 67.28  0  495 THR A N   1 
ATOM   3917 C  CA  . THR A 1 496 ? 155.321 150.318 148.730 1.00 67.28  0  495 THR A CA  1 
ATOM   3918 C  C   . THR A 1 496 ? 154.411 150.024 149.921 1.00 67.28  0  495 THR A C   1 
ATOM   3919 O  O   . THR A 1 496 ? 153.305 149.495 149.781 1.00 67.28  0  495 THR A O   1 
ATOM   3920 C  CB  . THR A 1 496 ? 155.421 151.825 148.500 1.00 67.28  0  495 THR A CB  1 
ATOM   3921 O  OG1 . THR A 1 496 ? 154.130 152.344 148.158 1.00 67.28  0  495 THR A OG1 1 
ATOM   3922 C  CG2 . THR A 1 496 ? 156.395 152.127 147.373 1.00 67.28  0  495 THR A CG2 1 
ATOM   3923 N  N   . GLU A 1 497 ? 154.899 150.371 151.115 1.00 67.28  0  496 GLU A N   1 
ATOM   3924 C  CA  . GLU A 1 497 ? 154.111 150.152 152.323 1.00 67.28  0  496 GLU A CA  1 
ATOM   3925 C  C   . GLU A 1 497 ? 152.831 150.979 152.308 1.00 67.28  0  496 GLU A C   1 
ATOM   3926 O  O   . GLU A 1 497 ? 151.765 150.487 152.691 1.00 67.28  0  496 GLU A O   1 
ATOM   3927 C  CB  . GLU A 1 497 ? 154.940 150.472 153.566 1.00 67.28  0  496 GLU A CB  1 
ATOM   3928 C  CG  . GLU A 1 497 ? 155.986 149.430 153.918 1.00 67.28  0  496 GLU A CG  1 
ATOM   3929 C  CD  . GLU A 1 497 ? 156.786 149.803 155.150 1.00 67.28  0  496 GLU A CD  1 
ATOM   3930 O  OE1 . GLU A 1 497 ? 156.619 150.937 155.647 1.00 67.28  0  496 GLU A OE1 1 
ATOM   3931 O  OE2 . GLU A 1 497 ? 157.581 148.964 155.623 1.00 67.28  -1 496 GLU A OE2 1 
ATOM   3932 N  N   . ALA A 1 498 ? 152.916 152.238 151.870 1.00 67.28  0  497 ALA A N   1 
ATOM   3933 C  CA  . ALA A 1 498 ? 151.724 153.078 151.804 1.00 67.28  0  497 ALA A CA  1 
ATOM   3934 C  C   . ALA A 1 498 ? 150.707 152.520 150.817 1.00 67.28  0  497 ALA A C   1 
ATOM   3935 O  O   . ALA A 1 498 ? 149.499 152.514 151.089 1.00 67.28  0  497 ALA A O   1 
ATOM   3936 C  CB  . ALA A 1 498 ? 152.110 154.508 151.427 1.00 67.28  0  497 ALA A CB  1 
ATOM   3937 N  N   . GLU A 1 499 ? 151.177 152.048 149.661 1.00 67.28  0  498 GLU A N   1 
ATOM   3938 C  CA  . GLU A 1 499 ? 150.273 151.455 148.682 1.00 67.28  0  498 GLU A CA  1 
ATOM   3939 C  C   . GLU A 1 499 ? 149.644 150.176 149.218 1.00 67.28  0  498 GLU A C   1 
ATOM   3940 O  O   . GLU A 1 499 ? 148.473 149.894 148.947 1.00 67.28  0  498 GLU A O   1 
ATOM   3941 C  CB  . GLU A 1 499 ? 151.016 151.188 147.375 1.00 67.28  0  498 GLU A CB  1 
ATOM   3942 C  CG  . GLU A 1 499 ? 151.077 152.385 146.442 1.00 67.28  0  498 GLU A CG  1 
ATOM   3943 C  CD  . GLU A 1 499 ? 151.911 152.119 145.204 1.00 67.28  0  498 GLU A CD  1 
ATOM   3944 O  OE1 . GLU A 1 499 ? 151.485 151.300 144.362 1.00 67.28  0  498 GLU A OE1 1 
ATOM   3945 O  OE2 . GLU A 1 499 ? 152.993 152.729 145.070 1.00 67.28  -1 498 GLU A OE2 1 
ATOM   3946 N  N   . LEU A 1 500 ? 150.409 149.384 149.975 1.00 67.28  0  499 LEU A N   1 
ATOM   3947 C  CA  . LEU A 1 500 ? 149.842 148.198 150.608 1.00 67.28  0  499 LEU A CA  1 
ATOM   3948 C  C   . LEU A 1 500 ? 148.774 148.572 151.629 1.00 67.28  0  499 LEU A C   1 
ATOM   3949 O  O   . LEU A 1 500 ? 147.734 147.909 151.717 1.00 67.28  0  499 LEU A O   1 
ATOM   3950 C  CB  . LEU A 1 500 ? 150.948 147.372 151.262 1.00 67.28  0  499 LEU A CB  1 
ATOM   3951 C  CG  . LEU A 1 500 ? 150.590 145.935 151.638 1.00 67.28  0  499 LEU A CG  1 
ATOM   3952 C  CD1 . LEU A 1 500 ? 149.767 145.274 150.546 1.00 67.28  0  499 LEU A CD1 1 
ATOM   3953 C  CD2 . LEU A 1 500 ? 151.850 145.137 151.919 1.00 67.28  0  499 LEU A CD2 1 
ATOM   3954 N  N   . ILE A 1 501 ? 149.019 149.626 152.412 1.00 67.28  0  500 ILE A N   1 
ATOM   3955 C  CA  . ILE A 1 501 ? 148.015 150.107 153.359 1.00 67.28  0  500 ILE A CA  1 
ATOM   3956 C  C   . ILE A 1 501 ? 146.742 150.497 152.619 1.00 67.28  0  500 ILE A C   1 
ATOM   3957 O  O   . ILE A 1 501 ? 145.628 150.135 153.020 1.00 67.28  0  500 ILE A O   1 
ATOM   3958 C  CB  . ILE A 1 501 ? 148.565 151.292 154.175 1.00 67.28  0  500 ILE A CB  1 
ATOM   3959 C  CG1 . ILE A 1 501 ? 149.809 150.896 154.974 1.00 67.28  0  500 ILE A CG1 1 
ATOM   3960 C  CG2 . ILE A 1 501 ? 147.495 151.838 155.100 1.00 67.28  0  500 ILE A CG2 1 
ATOM   3961 C  CD1 . ILE A 1 501 ? 149.534 150.081 156.204 1.00 67.28  0  500 ILE A CD1 1 
ATOM   3962 N  N   . THR A 1 502 ? 146.895 151.242 151.521 1.00 67.28  0  501 THR A N   1 
ATOM   3963 C  CA  . THR A 1 502 ? 145.734 151.676 150.749 1.00 67.28  0  501 THR A CA  1 
ATOM   3964 C  C   . THR A 1 502 ? 144.980 150.487 150.166 1.00 67.28  0  501 THR A C   1 
ATOM   3965 O  O   . THR A 1 502 ? 143.745 150.447 150.207 1.00 67.28  0  501 THR A O   1 
ATOM   3966 C  CB  . THR A 1 502 ? 146.167 152.631 149.635 1.00 67.28  0  501 THR A CB  1 
ATOM   3967 O  OG1 . THR A 1 502 ? 146.758 153.802 150.210 1.00 67.28  0  501 THR A OG1 1 
ATOM   3968 C  CG2 . THR A 1 502 ? 144.972 153.042 148.789 1.00 67.28  0  501 THR A CG2 1 
ATOM   3969 N  N   . LEU A 1 503 ? 145.705 149.506 149.624 1.00 67.28  0  502 LEU A N   1 
ATOM   3970 C  CA  . LEU A 1 503 ? 145.058 148.340 149.031 1.00 67.28  0  502 LEU A CA  1 
ATOM   3971 C  C   . LEU A 1 503 ? 144.322 147.517 150.080 1.00 67.28  0  502 LEU A C   1 
ATOM   3972 O  O   . LEU A 1 503 ? 143.207 147.040 149.832 1.00 67.28  0  502 LEU A O   1 
ATOM   3973 C  CB  . LEU A 1 503 ? 146.092 147.482 148.303 1.00 67.28  0  502 LEU A CB  1 
ATOM   3974 C  CG  . LEU A 1 503 ? 146.229 147.735 146.802 1.00 67.28  0  502 LEU A CG  1 
ATOM   3975 C  CD1 . LEU A 1 503 ? 147.201 146.751 146.172 1.00 67.28  0  502 LEU A CD1 1 
ATOM   3976 C  CD2 . LEU A 1 503 ? 144.870 147.661 146.123 1.00 67.28  0  502 LEU A CD2 1 
ATOM   3977 N  N   . MET A 1 504 ? 144.928 147.335 151.255 1.00 67.28  0  503 MET A N   1 
ATOM   3978 C  CA  . MET A 1 504 ? 144.267 146.574 152.308 1.00 67.28  0  503 MET A CA  1 
ATOM   3979 C  C   . MET A 1 504 ? 143.053 147.311 152.854 1.00 67.28  0  503 MET A C   1 
ATOM   3980 O  O   . MET A 1 504 ? 142.058 146.675 153.218 1.00 67.28  0  503 MET A O   1 
ATOM   3981 C  CB  . MET A 1 504 ? 145.255 146.256 153.431 1.00 67.28  0  503 MET A CB  1 
ATOM   3982 C  CG  . MET A 1 504 ? 146.326 145.253 153.038 1.00 67.28  0  503 MET A CG  1 
ATOM   3983 S  SD  . MET A 1 504 ? 147.492 144.893 154.364 1.00 67.28  0  503 MET A SD  1 
ATOM   3984 C  CE  . MET A 1 504 ? 146.455 143.954 155.481 1.00 67.28  0  503 MET A CE  1 
ATOM   3985 N  N   . GLU A 1 505 ? 143.111 148.644 152.922 1.00 67.28  0  504 GLU A N   1 
ATOM   3986 C  CA  . GLU A 1 505 ? 141.937 149.404 153.337 1.00 67.28  0  504 GLU A CA  1 
ATOM   3987 C  C   . GLU A 1 505 ? 140.834 149.326 152.289 1.00 67.28  0  504 GLU A C   1 
ATOM   3988 O  O   . GLU A 1 505 ? 139.648 149.251 152.631 1.00 67.28  0  504 GLU A O   1 
ATOM   3989 C  CB  . GLU A 1 505 ? 142.329 150.857 153.614 1.00 67.28  0  504 GLU A CB  1 
ATOM   3990 C  CG  . GLU A 1 505 ? 141.245 151.701 154.277 1.00 67.28  0  504 GLU A CG  1 
ATOM   3991 C  CD  . GLU A 1 505 ? 140.246 152.273 153.288 1.00 67.28  0  504 GLU A CD  1 
ATOM   3992 O  OE1 . GLU A 1 505 ? 140.627 152.504 152.122 1.00 67.28  0  504 GLU A OE1 1 
ATOM   3993 O  OE2 . GLU A 1 505 ? 139.079 152.488 153.677 1.00 67.28  -1 504 GLU A OE2 1 
ATOM   3994 N  N   . LYS A 1 506 ? 141.204 149.344 151.007 1.00 67.28  0  505 LYS A N   1 
ATOM   3995 C  CA  . LYS A 1 506 ? 140.210 149.304 149.940 1.00 67.28  0  505 LYS A CA  1 
ATOM   3996 C  C   . LYS A 1 506 ? 139.521 147.947 149.871 1.00 67.28  0  505 LYS A C   1 
ATOM   3997 O  O   . LYS A 1 506 ? 138.288 147.868 149.811 1.00 67.28  0  505 LYS A O   1 
ATOM   3998 C  CB  . LYS A 1 506 ? 140.869 149.639 148.602 1.00 67.28  0  505 LYS A CB  1 
ATOM   3999 C  CG  . LYS A 1 506 ? 139.968 149.438 147.397 1.00 67.28  0  505 LYS A CG  1 
ATOM   4000 C  CD  . LYS A 1 506 ? 140.471 150.222 146.197 1.00 67.28  0  505 LYS A CD  1 
ATOM   4001 C  CE  . LYS A 1 506 ? 141.591 149.481 145.487 1.00 67.28  0  505 LYS A CE  1 
ATOM   4002 N  NZ  . LYS A 1 506 ? 142.027 150.185 144.250 1.00 67.28  1  505 LYS A NZ  1 
ATOM   4003 N  N   . HIS A 1 507 ? 140.298 146.864 149.881 1.00 67.28  0  506 HIS A N   1 
ATOM   4004 C  CA  . HIS A 1 507 ? 139.727 145.534 149.716 1.00 67.28  0  506 HIS A CA  1 
ATOM   4005 C  C   . HIS A 1 507 ? 139.074 145.002 150.984 1.00 67.28  0  506 HIS A C   1 
ATOM   4006 O  O   . HIS A 1 507 ? 138.404 143.965 150.925 1.00 67.28  0  506 HIS A O   1 
ATOM   4007 C  CB  . HIS A 1 507 ? 140.801 144.556 149.236 1.00 67.28  0  506 HIS A CB  1 
ATOM   4008 C  CG  . HIS A 1 507 ? 141.152 144.713 147.790 1.00 67.28  0  506 HIS A CG  1 
ATOM   4009 N  ND1 . HIS A 1 507 ? 142.202 144.043 147.201 1.00 67.28  0  506 HIS A ND1 1 
ATOM   4010 C  CD2 . HIS A 1 507 ? 140.590 145.463 146.813 1.00 67.28  0  506 HIS A CD2 1 
ATOM   4011 C  CE1 . HIS A 1 507 ? 142.273 144.374 145.924 1.00 67.28  0  506 HIS A CE1 1 
ATOM   4012 N  NE2 . HIS A 1 507 ? 141.305 145.234 145.663 1.00 67.28  0  506 HIS A NE2 1 
ATOM   4013 N  N   . GLY A 1 508 ? 139.246 145.677 152.118 1.00 67.28  0  507 GLY A N   1 
ATOM   4014 C  CA  . GLY A 1 508 ? 138.574 145.313 153.341 1.00 67.28  0  507 GLY A CA  1 
ATOM   4015 C  C   . GLY A 1 508 ? 139.362 144.420 154.274 1.00 67.28  0  507 GLY A C   1 
ATOM   4016 O  O   . GLY A 1 508 ? 138.996 144.304 155.449 1.00 67.28  0  507 GLY A O   1 
ATOM   4017 N  N   . ILE A 1 509 ? 140.428 143.785 153.796 1.00 67.28  0  508 ILE A N   1 
ATOM   4018 C  CA  . ILE A 1 509 ? 141.226 142.912 154.650 1.00 67.28  0  508 ILE A CA  1 
ATOM   4019 C  C   . ILE A 1 509 ? 142.080 143.774 155.573 1.00 67.28  0  508 ILE A C   1 
ATOM   4020 O  O   . ILE A 1 509 ? 142.807 144.666 155.122 1.00 67.28  0  508 ILE A O   1 
ATOM   4021 C  CB  . ILE A 1 509 ? 142.080 141.939 153.821 1.00 67.28  0  508 ILE A CB  1 
ATOM   4022 C  CG1 . ILE A 1 509 ? 143.083 142.676 152.931 1.00 67.28  0  508 ILE A CG1 1 
ATOM   4023 C  CG2 . ILE A 1 509 ? 141.190 141.032 152.987 1.00 67.28  0  508 ILE A CG2 1 
ATOM   4024 C  CD1 . ILE A 1 509 ? 144.093 141.764 152.279 1.00 67.28  0  508 ILE A CD1 1 
ATOM   4025 N  N   . GLY A 1 510 ? 141.957 143.537 156.873 1.00 67.28  0  509 GLY A N   1 
ATOM   4026 C  CA  . GLY A 1 510 ? 142.674 144.318 157.857 1.00 67.28  0  509 GLY A CA  1 
ATOM   4027 C  C   . GLY A 1 510 ? 141.798 145.386 158.477 1.00 67.28  0  509 GLY A C   1 
ATOM   4028 O  O   . GLY A 1 510 ? 141.586 146.447 157.883 1.00 67.28  0  509 GLY A O   1 
ATOM   4029 N  N   . THR A 1 511 ? 141.283 145.116 159.673 1.00 67.28  0  510 THR A N   1 
ATOM   4030 C  CA  . THR A 1 511 ? 140.466 146.071 160.405 1.00 67.28  0  510 THR A CA  1 
ATOM   4031 C  C   . THR A 1 511 ? 140.926 146.089 161.854 1.00 67.28  0  510 THR A C   1 
ATOM   4032 O  O   . THR A 1 511 ? 141.701 145.234 162.291 1.00 67.28  0  510 THR A O   1 
ATOM   4033 C  CB  . THR A 1 511 ? 138.970 145.736 160.319 1.00 67.28  0  510 THR A CB  1 
ATOM   4034 O  OG1 . THR A 1 511 ? 138.764 144.359 160.658 1.00 67.28  0  510 THR A OG1 1 
ATOM   4035 C  CG2 . THR A 1 511 ? 138.441 145.995 158.916 1.00 67.28  0  510 THR A CG2 1 
ATOM   4036 N  N   . ASP A 1 512 ? 140.436 147.080 162.598 1.00 67.28  0  511 ASP A N   1 
ATOM   4037 C  CA  . ASP A 1 512 ? 140.846 147.303 163.985 1.00 67.28  0  511 ASP A CA  1 
ATOM   4038 C  C   . ASP A 1 512 ? 142.363 147.463 164.083 1.00 67.28  0  511 ASP A C   1 
ATOM   4039 O  O   . ASP A 1 512 ? 142.998 146.986 165.026 1.00 67.28  0  511 ASP A O   1 
ATOM   4040 C  CB  . ASP A 1 512 ? 140.350 146.179 164.898 1.00 67.28  0  511 ASP A CB  1 
ATOM   4041 C  CG  . ASP A 1 512 ? 140.366 146.566 166.366 1.00 67.28  0  511 ASP A CG  1 
ATOM   4042 O  OD1 . ASP A 1 512 ? 140.736 147.717 166.677 1.00 67.28  0  511 ASP A OD1 1 
ATOM   4043 O  OD2 . ASP A 1 512 ? 140.009 145.717 167.208 1.00 67.28  -1 511 ASP A OD2 1 
ATOM   4044 N  N   . ALA A 1 513 ? 142.943 148.140 163.089 1.00 67.28  0  512 ALA A N   1 
ATOM   4045 C  CA  . ALA A 1 513 ? 144.376 148.436 163.047 1.00 67.28  0  512 ALA A CA  1 
ATOM   4046 C  C   . ALA A 1 513 ? 145.228 147.171 163.149 1.00 67.28  0  512 ALA A C   1 
ATOM   4047 O  O   . ALA A 1 513 ? 146.249 147.142 163.839 1.00 67.28  0  512 ALA A O   1 
ATOM   4048 C  CB  . ALA A 1 513 ? 144.762 149.439 164.136 1.00 67.28  0  512 ALA A CB  1 
ATOM   4049 N  N   . SER A 1 514 ? 144.806 146.113 162.456 1.00 67.28  0  513 SER A N   1 
ATOM   4050 C  CA  . SER A 1 514 ? 145.603 144.898 162.354 1.00 67.28  0  513 SER A CA  1 
ATOM   4051 C  C   . SER A 1 514 ? 146.483 144.872 161.110 1.00 67.28  0  513 SER A C   1 
ATOM   4052 O  O   . SER A 1 514 ? 147.276 143.935 160.946 1.00 67.28  0  513 SER A O   1 
ATOM   4053 C  CB  . SER A 1 514 ? 144.692 143.666 162.366 1.00 67.28  0  513 SER A CB  1 
ATOM   4054 O  OG  . SER A 1 514 ? 145.450 142.474 162.249 1.00 67.28  0  513 SER A OG  1 
ATOM   4055 N  N   . ILE A 1 515 ? 146.355 145.874 160.237 1.00 67.28  0  514 ILE A N   1 
ATOM   4056 C  CA  . ILE A 1 515 ? 147.218 145.948 159.057 1.00 67.28  0  514 ILE A CA  1 
ATOM   4057 C  C   . ILE A 1 515 ? 148.695 146.043 159.426 1.00 67.28  0  514 ILE A C   1 
ATOM   4058 O  O   . ILE A 1 515 ? 149.510 145.348 158.795 1.00 67.28  0  514 ILE A O   1 
ATOM   4059 C  CB  . ILE A 1 515 ? 146.761 147.099 158.143 1.00 67.28  0  514 ILE A CB  1 
ATOM   4060 C  CG1 . ILE A 1 515 ? 145.347 146.836 157.627 1.00 67.28  0  514 ILE A CG1 1 
ATOM   4061 C  CG2 . ILE A 1 515 ? 147.707 147.252 156.980 1.00 67.28  0  514 ILE A CG2 1 
ATOM   4062 C  CD1 . ILE A 1 515 ? 144.717 148.022 156.934 1.00 67.28  0  514 ILE A CD1 1 
ATOM   4063 N  N   . PRO A 1 516 ? 149.117 146.886 160.382 1.00 67.28  0  515 PRO A N   1 
ATOM   4064 C  CA  . PRO A 1 516 ? 150.531 146.845 160.788 1.00 67.28  0  515 PRO A CA  1 
ATOM   4065 C  C   . PRO A 1 516 ? 150.959 145.485 161.300 1.00 67.28  0  515 PRO A C   1 
ATOM   4066 O  O   . PRO A 1 516 ? 152.087 145.056 161.033 1.00 67.28  0  515 PRO A O   1 
ATOM   4067 C  CB  . PRO A 1 516 ? 150.616 147.914 161.886 1.00 67.28  0  515 PRO A CB  1 
ATOM   4068 C  CG  . PRO A 1 516 ? 149.470 148.803 161.645 1.00 67.28  0  515 PRO A CG  1 
ATOM   4069 C  CD  . PRO A 1 516 ? 148.381 147.940 161.104 1.00 67.28  0  515 PRO A CD  1 
ATOM   4070 N  N   . VAL A 1 517 ? 150.082 144.789 162.026 1.00 67.28  0  516 VAL A N   1 
ATOM   4071 C  CA  . VAL A 1 517 ? 150.420 143.462 162.536 1.00 67.28  0  516 VAL A CA  1 
ATOM   4072 C  C   . VAL A 1 517 ? 150.671 142.502 161.381 1.00 67.28  0  516 VAL A C   1 
ATOM   4073 O  O   . VAL A 1 517 ? 151.655 141.754 161.374 1.00 67.28  0  516 VAL A O   1 
ATOM   4074 C  CB  . VAL A 1 517 ? 149.311 142.945 163.468 1.00 67.28  0  516 VAL A CB  1 
ATOM   4075 C  CG1 . VAL A 1 517 ? 149.658 141.558 163.996 1.00 67.28  0  516 VAL A CG1 1 
ATOM   4076 C  CG2 . VAL A 1 517 ? 149.088 143.917 164.612 1.00 67.28  0  516 VAL A CG2 1 
ATOM   4077 N  N   . HIS A 1 518 ? 149.790 142.523 160.378 1.00 67.28  0  517 HIS A N   1 
ATOM   4078 C  CA  . HIS A 1 518 ? 149.950 141.622 159.239 1.00 67.28  0  517 HIS A CA  1 
ATOM   4079 C  C   . HIS A 1 518 ? 151.204 141.953 158.438 1.00 67.28  0  517 HIS A C   1 
ATOM   4080 O  O   . HIS A 1 518 ? 151.940 141.049 158.019 1.00 67.28  0  517 HIS A O   1 
ATOM   4081 C  CB  . HIS A 1 518 ? 148.712 141.686 158.348 1.00 67.28  0  517 HIS A CB  1 
ATOM   4082 C  CG  . HIS A 1 518 ? 147.451 141.267 159.037 1.00 67.28  0  517 HIS A CG  1 
ATOM   4083 N  ND1 . HIS A 1 518 ? 146.219 141.796 158.719 1.00 67.28  0  517 HIS A ND1 1 
ATOM   4084 C  CD2 . HIS A 1 518 ? 147.231 140.369 160.026 1.00 67.28  0  517 HIS A CD2 1 
ATOM   4085 C  CE1 . HIS A 1 518 ? 145.295 141.245 159.485 1.00 67.28  0  517 HIS A CE1 1 
ATOM   4086 N  NE2 . HIS A 1 518 ? 145.883 140.374 160.286 1.00 67.28  0  517 HIS A NE2 1 
ATOM   4087 N  N   . ILE A 1 519 ? 151.462 143.244 158.213 1.00 67.28  0  518 ILE A N   1 
ATOM   4088 C  CA  . ILE A 1 519 ? 152.644 143.643 157.454 1.00 67.28  0  518 ILE A CA  1 
ATOM   4089 C  C   . ILE A 1 519 ? 153.913 143.244 158.194 1.00 67.28  0  518 ILE A C   1 
ATOM   4090 O  O   . ILE A 1 519 ? 154.857 142.709 157.598 1.00 67.28  0  518 ILE A O   1 
ATOM   4091 C  CB  . ILE A 1 519 ? 152.606 145.154 157.158 1.00 67.28  0  518 ILE A CB  1 
ATOM   4092 C  CG1 . ILE A 1 519 ? 151.565 145.458 156.081 1.00 67.28  0  518 ILE A CG1 1 
ATOM   4093 C  CG2 . ILE A 1 519 ? 153.976 145.652 156.728 1.00 67.28  0  518 ILE A CG2 1 
ATOM   4094 C  CD1 . ILE A 1 519 ? 151.446 146.925 155.746 1.00 67.28  0  518 ILE A CD1 1 
ATOM   4095 N  N   . ASN A 1 520 ? 153.956 143.484 159.507 1.00 67.28  0  519 ASN A N   1 
ATOM   4096 C  CA  . ASN A 1 520 ? 155.123 143.095 160.287 1.00 67.28  0  519 ASN A CA  1 
ATOM   4097 C  C   . ASN A 1 520 ? 155.288 141.584 160.328 1.00 67.28  0  519 ASN A C   1 
ATOM   4098 O  O   . ASN A 1 520 ? 156.418 141.091 160.369 1.00 67.28  0  519 ASN A O   1 
ATOM   4099 C  CB  . ASN A 1 520 ? 155.024 143.657 161.704 1.00 67.28  0  519 ASN A CB  1 
ATOM   4100 C  CG  . ASN A 1 520 ? 156.284 143.422 162.510 1.00 67.28  0  519 ASN A CG  1 
ATOM   4101 O  OD1 . ASN A 1 520 ? 156.234 142.900 163.624 1.00 67.28  0  519 ASN A OD1 1 
ATOM   4102 N  ND2 . ASN A 1 520 ? 157.425 143.809 161.951 1.00 67.28  0  519 ASN A ND2 1 
ATOM   4103 N  N   . ASN A 1 521 ? 154.186 140.832 160.313 1.00 67.28  0  520 ASN A N   1 
ATOM   4104 C  CA  . ASN A 1 521 ? 154.290 139.377 160.287 1.00 67.28  0  520 ASN A CA  1 
ATOM   4105 C  C   . ASN A 1 521 ? 154.898 138.894 158.976 1.00 67.28  0  520 ASN A C   1 
ATOM   4106 O  O   . ASN A 1 521 ? 155.827 138.074 158.974 1.00 67.28  0  520 ASN A O   1 
ATOM   4107 C  CB  . ASN A 1 521 ? 152.913 138.751 160.508 1.00 67.28  0  520 ASN A CB  1 
ATOM   4108 C  CG  . ASN A 1 521 ? 152.671 138.374 161.956 1.00 67.28  0  520 ASN A CG  1 
ATOM   4109 O  OD1 . ASN A 1 521 ? 153.517 138.606 162.819 1.00 67.28  0  520 ASN A OD1 1 
ATOM   4110 N  ND2 . ASN A 1 521 ? 151.509 137.793 162.231 1.00 67.28  0  520 ASN A ND2 1 
ATOM   4111 N  N   . ILE A 1 522 ? 154.396 139.403 157.847 1.00 67.28  0  521 ILE A N   1 
ATOM   4112 C  CA  . ILE A 1 522 ? 154.940 139.000 156.553 1.00 67.28  0  521 ILE A CA  1 
ATOM   4113 C  C   . ILE A 1 522 ? 156.313 139.591 156.280 1.00 67.28  0  521 ILE A C   1 
ATOM   4114 O  O   . ILE A 1 522 ? 156.976 139.174 155.325 1.00 67.28  0  521 ILE A O   1 
ATOM   4115 C  CB  . ILE A 1 522 ? 153.984 139.364 155.398 1.00 67.28  0  521 ILE A CB  1 
ATOM   4116 C  CG1 . ILE A 1 522 ? 154.085 140.852 155.058 1.00 67.28  0  521 ILE A CG1 1 
ATOM   4117 C  CG2 . ILE A 1 522 ? 152.561 138.955 155.733 1.00 67.28  0  521 ILE A CG2 1 
ATOM   4118 C  CD1 . ILE A 1 522 ? 153.485 141.212 153.719 1.00 67.28  0  521 ILE A CD1 1 
ATOM   4119 N  N   . CYS A 1 523 ? 156.751 140.564 157.079 1.00 67.28  0  522 CYS A N   1 
ATOM   4120 C  CA  . CYS A 1 523 ? 158.127 141.040 156.992 1.00 67.28  0  522 CYS A CA  1 
ATOM   4121 C  C   . CYS A 1 523 ? 159.072 140.235 157.877 1.00 67.28  0  522 CYS A C   1 
ATOM   4122 O  O   . CYS A 1 523 ? 160.210 139.964 157.479 1.00 67.28  0  522 CYS A O   1 
ATOM   4123 C  CB  . CYS A 1 523 ? 158.197 142.523 157.366 1.00 67.28  0  522 CYS A CB  1 
ATOM   4124 S  SG  . CYS A 1 523 ? 157.617 143.647 156.077 1.00 67.28  0  522 CYS A SG  1 
ATOM   4125 N  N   . GLN A 1 524 ? 158.623 139.851 159.074 1.00 67.28  0  523 GLN A N   1 
ATOM   4126 C  CA  . GLN A 1 524 ? 159.436 139.018 159.952 1.00 67.28  0  523 GLN A CA  1 
ATOM   4127 C  C   . GLN A 1 524 ? 159.642 137.638 159.347 1.00 67.28  0  523 GLN A C   1 
ATOM   4128 O  O   . GLN A 1 524 ? 160.774 137.145 159.270 1.00 67.28  0  523 GLN A O   1 
ATOM   4129 C  CB  . GLN A 1 524 ? 158.782 138.914 161.330 1.00 67.28  0  523 GLN A CB  1 
ATOM   4130 C  CG  . GLN A 1 524 ? 159.378 139.845 162.371 1.00 67.28  0  523 GLN A CG  1 
ATOM   4131 C  CD  . GLN A 1 524 ? 158.944 139.496 163.780 1.00 67.28  0  523 GLN A CD  1 
ATOM   4132 O  OE1 . GLN A 1 524 ? 157.755 139.324 164.051 1.00 67.28  0  523 GLN A OE1 1 
ATOM   4133 N  NE2 . GLN A 1 524 ? 159.908 139.391 164.687 1.00 67.28  0  523 GLN A NE2 1 
ATOM   4134 N  N   . ARG A 1 525 ? 158.561 136.995 158.913 1.00 67.28  0  524 ARG A N   1 
ATOM   4135 C  CA  . ARG A 1 525 ? 158.701 135.825 158.059 1.00 67.28  0  524 ARG A CA  1 
ATOM   4136 C  C   . ARG A 1 525 ? 159.251 136.281 156.715 1.00 67.28  0  524 ARG A C   1 
ATOM   4137 O  O   . ARG A 1 525 ? 158.671 137.159 156.069 1.00 67.28  0  524 ARG A O   1 
ATOM   4138 C  CB  . ARG A 1 525 ? 157.360 135.115 157.894 1.00 67.28  0  524 ARG A CB  1 
ATOM   4139 C  CG  . ARG A 1 525 ? 156.850 134.466 159.170 1.00 67.28  0  524 ARG A CG  1 
ATOM   4140 C  CD  . ARG A 1 525 ? 155.426 133.960 159.015 1.00 67.28  0  524 ARG A CD  1 
ATOM   4141 N  NE  . ARG A 1 525 ? 155.013 133.153 160.157 1.00 67.28  0  524 ARG A NE  1 
ATOM   4142 C  CZ  . ARG A 1 525 ? 153.774 132.734 160.371 1.00 67.28  0  524 ARG A CZ  1 
ATOM   4143 N  NH1 . ARG A 1 525 ? 152.791 133.026 159.535 1.00 67.28  1  524 ARG A NH1 1 
ATOM   4144 N  NH2 . ARG A 1 525 ? 153.514 132.002 161.451 1.00 67.28  0  524 ARG A NH2 1 
ATOM   4145 N  N   . ASN A 1 526 ? 160.367 135.694 156.291 1.00 67.28  0  525 ASN A N   1 
ATOM   4146 C  CA  . ASN A 1 526 ? 161.114 136.252 155.171 1.00 67.28  0  525 ASN A CA  1 
ATOM   4147 C  C   . ASN A 1 526 ? 160.394 136.030 153.849 1.00 67.28  0  525 ASN A C   1 
ATOM   4148 O  O   . ASN A 1 526 ? 160.869 135.283 152.988 1.00 67.28  0  525 ASN A O   1 
ATOM   4149 C  CB  . ASN A 1 526 ? 162.521 135.656 155.120 1.00 67.28  0  525 ASN A CB  1 
ATOM   4150 C  CG  . ASN A 1 526 ? 163.448 136.267 156.151 1.00 67.28  0  525 ASN A CG  1 
ATOM   4151 O  OD1 . ASN A 1 526 ? 163.941 135.580 157.044 1.00 67.28  0  525 ASN A OD1 1 
ATOM   4152 N  ND2 . ASN A 1 526 ? 163.685 137.568 156.034 1.00 67.28  0  525 ASN A ND2 1 
ATOM   4153 N  N   . TYR A 1 527 ? 159.244 136.681 153.683 1.00 67.28  0  526 TYR A N   1 
ATOM   4154 C  CA  . TYR A 1 527 ? 158.502 136.655 152.431 1.00 67.28  0  526 TYR A CA  1 
ATOM   4155 C  C   . TYR A 1 527 ? 158.668 137.930 151.620 1.00 67.28  0  526 TYR A C   1 
ATOM   4156 O  O   . TYR A 1 527 ? 158.589 137.882 150.388 1.00 67.28  0  526 TYR A O   1 
ATOM   4157 C  CB  . TYR A 1 527 ? 157.012 136.423 152.700 1.00 67.28  0  526 TYR A CB  1 
ATOM   4158 C  CG  . TYR A 1 527 ? 156.699 135.103 153.371 1.00 67.28  0  526 TYR A CG  1 
ATOM   4159 C  CD1 . TYR A 1 527 ? 157.579 134.033 153.290 1.00 67.28  0  526 TYR A CD1 1 
ATOM   4160 C  CD2 . TYR A 1 527 ? 155.523 134.928 154.085 1.00 67.28  0  526 TYR A CD2 1 
ATOM   4161 C  CE1 . TYR A 1 527 ? 157.297 132.828 153.902 1.00 67.28  0  526 TYR A CE1 1 
ATOM   4162 C  CE2 . TYR A 1 527 ? 155.232 133.727 154.699 1.00 67.28  0  526 TYR A CE2 1 
ATOM   4163 C  CZ  . TYR A 1 527 ? 156.122 132.681 154.604 1.00 67.28  0  526 TYR A CZ  1 
ATOM   4164 O  OH  . TYR A 1 527 ? 155.837 131.482 155.215 1.00 67.28  0  526 TYR A OH  1 
ATOM   4165 N  N   . VAL A 1 528 ? 158.897 139.063 152.279 1.00 67.28  0  527 VAL A N   1 
ATOM   4166 C  CA  . VAL A 1 528 ? 159.152 140.334 151.612 1.00 67.28  0  527 VAL A CA  1 
ATOM   4167 C  C   . VAL A 1 528 ? 160.361 140.993 152.260 1.00 67.28  0  527 VAL A C   1 
ATOM   4168 O  O   . VAL A 1 528 ? 160.597 140.840 153.463 1.00 67.28  0  527 VAL A O   1 
ATOM   4169 C  CB  . VAL A 1 528 ? 157.930 141.276 151.663 1.00 67.28  0  527 VAL A CB  1 
ATOM   4170 C  CG1 . VAL A 1 528 ? 156.770 140.687 150.889 1.00 67.28  0  527 VAL A CG1 1 
ATOM   4171 C  CG2 . VAL A 1 528 ? 157.523 141.548 153.103 1.00 67.28  0  527 VAL A CG2 1 
ATOM   4172 N  N   . THR A 1 529 ? 161.133 141.714 151.456 1.00 67.28  0  528 THR A N   1 
ATOM   4173 C  CA  . THR A 1 529 ? 162.258 142.503 151.931 1.00 67.28  0  528 THR A CA  1 
ATOM   4174 C  C   . THR A 1 529 ? 161.943 143.982 151.755 1.00 67.28  0  528 THR A C   1 
ATOM   4175 O  O   . THR A 1 529 ? 161.319 144.380 150.765 1.00 67.28  0  528 THR A O   1 
ATOM   4176 C  CB  . THR A 1 529 ? 163.543 142.148 151.179 1.00 67.28  0  528 THR A CB  1 
ATOM   4177 O  OG1 . THR A 1 529 ? 163.292 142.161 149.768 1.00 67.28  0  528 THR A OG1 1 
ATOM   4178 C  CG2 . THR A 1 529 ? 164.036 140.770 151.589 1.00 67.28  0  528 THR A CG2 1 
ATOM   4179 N  N   . VAL A 1 530 ? 162.372 144.792 152.720 1.00 67.28  0  529 VAL A N   1 
ATOM   4180 C  CA  . VAL A 1 530 ? 162.084 146.227 152.717 1.00 67.28  0  529 VAL A CA  1 
ATOM   4181 C  C   . VAL A 1 530 ? 163.277 146.914 152.059 1.00 67.28  0  529 VAL A C   1 
ATOM   4182 O  O   . VAL A 1 530 ? 164.243 147.303 152.714 1.00 67.28  0  529 VAL A O   1 
ATOM   4183 C  CB  . VAL A 1 530 ? 161.806 146.759 154.119 1.00 67.28  0  529 VAL A CB  1 
ATOM   4184 C  CG1 . VAL A 1 530 ? 161.181 148.141 154.042 1.00 67.28  0  529 VAL A CG1 1 
ATOM   4185 C  CG2 . VAL A 1 530 ? 160.899 145.802 154.877 1.00 67.28  0  529 VAL A CG2 1 
ATOM   4186 N  N   . GLU A 1 531 ? 163.201 147.063 150.740 1.00 67.28  0  530 GLU A N   1 
ATOM   4187 C  CA  . GLU A 1 531 ? 164.220 147.765 149.982 1.00 67.28  0  530 GLU A CA  1 
ATOM   4188 C  C   . GLU A 1 531 ? 163.991 149.274 150.053 1.00 67.28  0  530 GLU A C   1 
ATOM   4189 O  O   . GLU A 1 531 ? 162.931 149.754 150.474 1.00 67.28  0  530 GLU A O   1 
ATOM   4190 C  CB  . GLU A 1 531 ? 164.227 147.293 148.529 1.00 67.28  0  530 GLU A CB  1 
ATOM   4191 C  CG  . GLU A 1 531 ? 164.360 145.789 148.367 1.00 67.28  0  530 GLU A CG  1 
ATOM   4192 C  CD  . GLU A 1 531 ? 165.785 145.304 148.551 1.00 67.28  0  530 GLU A CD  1 
ATOM   4193 O  OE1 . GLU A 1 531 ? 166.212 145.137 149.713 1.00 67.28  0  530 GLU A OE1 1 
ATOM   4194 O  OE2 . GLU A 1 531 ? 166.477 145.090 147.534 1.00 67.28  -1 530 GLU A OE2 1 
ATOM   4195 N  N   . SER A 1 532 ? 165.000 150.017 149.597 1.00 67.28  0  531 SER A N   1 
ATOM   4196 C  CA  . SER A 1 532 ? 165.022 151.467 149.741 1.00 67.28  0  531 SER A CA  1 
ATOM   4197 C  C   . SER A 1 532 ? 163.788 152.099 149.111 1.00 67.28  0  531 SER A C   1 
ATOM   4198 O  O   . SER A 1 532 ? 163.274 151.638 148.088 1.00 67.28  0  531 SER A O   1 
ATOM   4199 C  CB  . SER A 1 532 ? 166.287 152.043 149.104 1.00 67.28  0  531 SER A CB  1 
ATOM   4200 O  OG  . SER A 1 532 ? 166.201 152.023 147.690 1.00 67.28  0  531 SER A OG  1 
ATOM   4201 N  N   . GLY A 1 533 ? 163.314 153.172 149.737 1.00 67.28  0  532 GLY A N   1 
ATOM   4202 C  CA  . GLY A 1 533 ? 162.037 153.747 149.382 1.00 67.28  0  532 GLY A CA  1 
ATOM   4203 C  C   . GLY A 1 533 ? 160.852 153.063 150.019 1.00 67.28  0  532 GLY A C   1 
ATOM   4204 O  O   . GLY A 1 533 ? 159.716 153.302 149.592 1.00 67.28  0  532 GLY A O   1 
ATOM   4205 N  N   . ARG A 1 534 ? 161.086 152.219 151.027 1.00 67.28  0  533 ARG A N   1 
ATOM   4206 C  CA  . ARG A 1 534 ? 160.036 151.440 151.683 1.00 67.28  0  533 ARG A CA  1 
ATOM   4207 C  C   . ARG A 1 534 ? 159.281 150.582 150.670 1.00 67.28  0  533 ARG A C   1 
ATOM   4208 O  O   . ARG A 1 534 ? 158.052 150.613 150.585 1.00 67.28  0  533 ARG A O   1 
ATOM   4209 C  CB  . ARG A 1 534 ? 159.078 152.345 152.462 1.00 67.28  0  533 ARG A CB  1 
ATOM   4210 C  CG  . ARG A 1 534 ? 159.712 153.057 153.647 1.00 67.28  0  533 ARG A CG  1 
ATOM   4211 C  CD  . ARG A 1 534 ? 160.662 152.144 154.403 1.00 67.28  0  533 ARG A CD  1 
ATOM   4212 N  NE  . ARG A 1 534 ? 159.954 151.247 155.308 1.00 67.28  0  533 ARG A NE  1 
ATOM   4213 C  CZ  . ARG A 1 534 ? 160.511 150.639 156.346 1.00 67.28  0  533 ARG A CZ  1 
ATOM   4214 N  NH1 . ARG A 1 534 ? 161.787 150.813 156.647 1.00 67.28  1  533 ARG A NH1 1 
ATOM   4215 N  NH2 . ARG A 1 534 ? 159.769 149.833 157.099 1.00 67.28  0  533 ARG A NH2 1 
ATOM   4216 N  N   . ARG A 1 535 ? 160.033 149.806 149.894 1.00 67.28  0  534 ARG A N   1 
ATOM   4217 C  CA  . ARG A 1 535 ? 159.457 148.955 148.861 1.00 67.28  0  534 ARG A CA  1 
ATOM   4218 C  C   . ARG A 1 535 ? 159.474 147.504 149.322 1.00 67.28  0  534 ARG A C   1 
ATOM   4219 O  O   . ARG A 1 535 ? 160.497 147.016 149.809 1.00 67.28  0  534 ARG A O   1 
ATOM   4220 C  CB  . ARG A 1 535 ? 160.221 149.103 147.544 1.00 67.28  0  534 ARG A CB  1 
ATOM   4221 C  CG  . ARG A 1 535 ? 160.067 150.468 146.891 1.00 67.28  0  534 ARG A CG  1 
ATOM   4222 C  CD  . ARG A 1 535 ? 160.679 150.493 145.501 1.00 67.28  0  534 ARG A CD  1 
ATOM   4223 N  NE  . ARG A 1 535 ? 162.111 150.221 145.527 1.00 67.28  0  534 ARG A NE  1 
ATOM   4224 C  CZ  . ARG A 1 535 ? 162.778 149.626 144.547 1.00 67.28  0  534 ARG A CZ  1 
ATOM   4225 N  NH1 . ARG A 1 535 ? 162.172 149.226 143.442 1.00 67.28  1  534 ARG A NH1 1 
ATOM   4226 N  NH2 . ARG A 1 535 ? 164.087 149.428 144.680 1.00 67.28  0  534 ARG A NH2 1 
ATOM   4227 N  N   . LEU A 1 536 ? 158.345 146.820 149.170 1.00 67.28  0  535 LEU A N   1 
ATOM   4228 C  CA  . LEU A 1 536 ? 158.223 145.419 149.568 1.00 67.28  0  535 LEU A CA  1 
ATOM   4229 C  C   . LEU A 1 536 ? 158.552 144.553 148.359 1.00 67.28  0  535 LEU A C   1 
ATOM   4230 O  O   . LEU A 1 536 ? 157.708 144.340 147.485 1.00 67.28  0  535 LEU A O   1 
ATOM   4231 C  CB  . LEU A 1 536 ? 156.828 145.118 150.104 1.00 67.28  0  535 LEU A CB  1 
ATOM   4232 C  CG  . LEU A 1 536 ? 156.457 145.719 151.459 1.00 67.28  0  535 LEU A CG  1 
ATOM   4233 C  CD1 . LEU A 1 536 ? 155.785 147.062 151.268 1.00 67.28  0  535 LEU A CD1 1 
ATOM   4234 C  CD2 . LEU A 1 536 ? 155.562 144.773 152.244 1.00 67.28  0  535 LEU A CD2 1 
ATOM   4235 N  N   . LYS A 1 537 ? 159.784 144.052 148.310 1.00 67.28  0  536 LYS A N   1 
ATOM   4236 C  CA  . LYS A 1 537 ? 160.194 143.157 147.239 1.00 67.28  0  536 LYS A CA  1 
ATOM   4237 C  C   . LYS A 1 537 ? 159.956 141.718 147.671 1.00 67.28  0  536 LYS A C   1 
ATOM   4238 O  O   . LYS A 1 537 ? 160.559 141.274 148.657 1.00 67.28  0  536 LYS A O   1 
ATOM   4239 C  CB  . LYS A 1 537 ? 161.658 143.363 146.895 1.00 67.28  0  536 LYS A CB  1 
ATOM   4240 C  CG  . LYS A 1 537 ? 162.197 142.377 145.874 1.00 67.28  0  536 LYS A CG  1 
ATOM   4241 C  CD  . LYS A 1 537 ? 163.636 142.690 145.506 1.00 67.28  0  536 LYS A CD  1 
ATOM   4242 C  CE  . LYS A 1 537 ? 164.226 141.606 144.621 1.00 67.28  0  536 LYS A CE  1 
ATOM   4243 N  NZ  . LYS A 1 537 ? 163.531 141.528 143.308 1.00 67.28  1  536 LYS A NZ  1 
ATOM   4244 N  N   . PRO A 1 538 ? 159.081 140.972 146.999 1.00 67.28  0  537 PRO A N   1 
ATOM   4245 C  CA  . PRO A 1 538 ? 158.832 139.586 147.410 1.00 67.28  0  537 PRO A CA  1 
ATOM   4246 C  C   . PRO A 1 538 ? 160.075 138.725 147.246 1.00 67.28  0  537 PRO A C   1 
ATOM   4247 O  O   . PRO A 1 538 ? 160.861 138.904 146.314 1.00 67.28  0  537 PRO A O   1 
ATOM   4248 C  CB  . PRO A 1 538 ? 157.707 139.134 146.472 1.00 67.28  0  537 PRO A CB  1 
ATOM   4249 C  CG  . PRO A 1 538 ? 157.089 140.396 145.973 1.00 67.28  0  537 PRO A CG  1 
ATOM   4250 C  CD  . PRO A 1 538 ? 158.206 141.385 145.893 1.00 67.28  0  537 PRO A CD  1 
ATOM   4251 N  N   . THR A 1 539 ? 160.245 137.784 148.167 1.00 67.28  0  538 THR A N   1 
ATOM   4252 C  CA  . THR A 1 539 ? 161.350 136.843 148.102 1.00 67.28  0  538 THR A CA  1 
ATOM   4253 C  C   . THR A 1 539 ? 160.943 135.603 147.310 1.00 67.28  0  538 THR A C   1 
ATOM   4254 O  O   . THR A 1 539 ? 159.780 135.420 146.939 1.00 67.28  0  538 THR A O   1 
ATOM   4255 C  CB  . THR A 1 539 ? 161.809 136.449 149.505 1.00 67.28  0  538 THR A CB  1 
ATOM   4256 O  OG1 . THR A 1 539 ? 160.736 135.795 150.194 1.00 67.28  0  538 THR A OG1 1 
ATOM   4257 C  CG2 . THR A 1 539 ? 162.230 137.680 150.292 1.00 67.28  0  538 THR A CG2 1 
ATOM   4258 N  N   . ASN A 1 540 ? 161.927 134.738 147.050 1.00 67.28  0  539 ASN A N   1 
ATOM   4259 C  CA  . ASN A 1 540 ? 161.650 133.507 146.266 1.00 67.28  0  539 ASN A CA  1 
ATOM   4260 C  C   . ASN A 1 540 ? 160.626 132.661 147.020 1.00 67.28  0  539 ASN A C   1 
ATOM   4261 O  O   . ASN A 1 540 ? 159.658 132.204 146.383 1.00 67.28  0  539 ASN A O   1 
ATOM   4262 C  CB  . ASN A 1 540 ? 162.916 132.702 145.975 1.00 67.28  0  539 ASN A CB  1 
ATOM   4263 C  CG  . ASN A 1 540 ? 162.636 131.434 145.198 1.00 67.28  0  539 ASN A CG  1 
ATOM   4264 O  OD1 . ASN A 1 540 ? 163.071 130.352 145.588 1.00 67.28  0  539 ASN A OD1 1 
ATOM   4265 N  ND2 . ASN A 1 540 ? 161.906 131.555 144.102 1.00 67.28  0  539 ASN A ND2 1 
ATOM   4266 N  N   . LEU A 1 541 ? 160.829 132.471 148.323 1.00 67.28  0  540 LEU A N   1 
ATOM   4267 C  CA  . LEU A 1 541 ? 159.923 131.619 149.085 1.00 67.28  0  540 LEU A CA  1 
ATOM   4268 C  C   . LEU A 1 541 ? 158.496 132.146 149.027 1.00 67.28  0  540 LEU A C   1 
ATOM   4269 O  O   . LEU A 1 541 ? 157.553 131.385 148.786 1.00 67.28  0  540 LEU A O   1 
ATOM   4270 C  CB  . LEU A 1 541 ? 160.398 131.511 150.533 1.00 67.28  0  540 LEU A CB  1 
ATOM   4271 C  CG  . LEU A 1 541 ? 159.583 130.583 151.434 1.00 67.28  0  540 LEU A CG  1 
ATOM   4272 C  CD1 . LEU A 1 541 ? 159.656 129.145 150.946 1.00 67.28  0  540 LEU A CD1 1 
ATOM   4273 C  CD2 . LEU A 1 541 ? 160.051 130.693 152.875 1.00 67.28  0  540 LEU A CD2 1 
ATOM   4274 N  N   . GLY A 1 542 ? 158.320 133.451 149.233 1.00 67.28  0  541 GLY A N   1 
ATOM   4275 C  CA  . GLY A 1 542 ? 156.984 134.020 149.185 1.00 67.28  0  541 GLY A CA  1 
ATOM   4276 C  C   . GLY A 1 542 ? 156.352 133.914 147.811 1.00 67.28  0  541 GLY A C   1 
ATOM   4277 O  O   . GLY A 1 542 ? 155.171 133.577 147.684 1.00 67.28  0  541 GLY A O   1 
ATOM   4278 N  N   . ILE A 1 543 ? 157.131 134.196 146.764 1.00 67.28  0  542 ILE A N   1 
ATOM   4279 C  CA  . ILE A 1 543 ? 156.609 134.102 145.404 1.00 67.28  0  542 ILE A CA  1 
ATOM   4280 C  C   . ILE A 1 543 ? 156.152 132.680 145.109 1.00 67.28  0  542 ILE A C   1 
ATOM   4281 O  O   . ILE A 1 543 ? 155.052 132.459 144.587 1.00 67.28  0  542 ILE A O   1 
ATOM   4282 C  CB  . ILE A 1 543 ? 157.663 134.577 144.388 1.00 67.28  0  542 ILE A CB  1 
ATOM   4283 C  CG1 . ILE A 1 543 ? 157.854 136.090 144.487 1.00 67.28  0  542 ILE A CG1 1 
ATOM   4284 C  CG2 . ILE A 1 543 ? 157.268 134.180 142.979 1.00 67.28  0  542 ILE A CG2 1 
ATOM   4285 C  CD1 . ILE A 1 543 ? 159.141 136.587 143.869 1.00 67.28  0  542 ILE A CD1 1 
ATOM   4286 N  N   . VAL A 1 544 ? 156.984 131.694 145.454 1.00 67.28  0  543 VAL A N   1 
ATOM   4287 C  CA  . VAL A 1 544 ? 156.636 130.304 145.178 1.00 67.28  0  543 VAL A CA  1 
ATOM   4288 C  C   . VAL A 1 544 ? 155.415 129.884 145.988 1.00 67.28  0  543 VAL A C   1 
ATOM   4289 O  O   . VAL A 1 544 ? 154.512 129.214 145.468 1.00 67.28  0  543 VAL A O   1 
ATOM   4290 C  CB  . VAL A 1 544 ? 157.845 129.388 145.444 1.00 67.28  0  543 VAL A CB  1 
ATOM   4291 C  CG1 . VAL A 1 544 ? 157.445 127.938 145.320 1.00 67.28  0  543 VAL A CG1 1 
ATOM   4292 C  CG2 . VAL A 1 544 ? 158.964 129.693 144.470 1.00 67.28  0  543 VAL A CG2 1 
ATOM   4293 N  N   . LEU A 1 545 ? 155.356 130.275 147.265 1.00 67.28  0  544 LEU A N   1 
ATOM   4294 C  CA  . LEU A 1 545 ? 154.216 129.910 148.101 1.00 67.28  0  544 LEU A CA  1 
ATOM   4295 C  C   . LEU A 1 545 ? 152.917 130.466 147.535 1.00 67.28  0  544 LEU A C   1 
ATOM   4296 O  O   . LEU A 1 545 ? 151.924 129.740 147.400 1.00 67.28  0  544 LEU A O   1 
ATOM   4297 C  CB  . LEU A 1 545 ? 154.421 130.406 149.535 1.00 67.28  0  544 LEU A CB  1 
ATOM   4298 C  CG  . LEU A 1 545 ? 155.470 129.736 150.424 1.00 67.28  0  544 LEU A CG  1 
ATOM   4299 C  CD1 . LEU A 1 545 ? 155.623 130.499 151.725 1.00 67.28  0  544 LEU A CD1 1 
ATOM   4300 C  CD2 . LEU A 1 545 ? 155.096 128.303 150.706 1.00 67.28  0  544 LEU A CD2 1 
ATOM   4301 N  N   . VAL A 1 546 ? 152.901 131.758 147.195 1.00 67.28  0  545 VAL A N   1 
ATOM   4302 C  CA  . VAL A 1 546 ? 151.658 132.347 146.710 1.00 67.28  0  545 VAL A CA  1 
ATOM   4303 C  C   . VAL A 1 546 ? 151.303 131.816 145.328 1.00 67.28  0  545 VAL A C   1 
ATOM   4304 O  O   . VAL A 1 546 ? 150.121 131.654 145.009 1.00 67.28  0  545 VAL A O   1 
ATOM   4305 C  CB  . VAL A 1 546 ? 151.729 133.883 146.725 1.00 67.28  0  545 VAL A CB  1 
ATOM   4306 C  CG1 . VAL A 1 546 ? 150.367 134.458 146.412 1.00 67.28  0  545 VAL A CG1 1 
ATOM   4307 C  CG2 . VAL A 1 546 ? 152.183 134.372 148.081 1.00 67.28  0  545 VAL A CG2 1 
ATOM   4308 N  N   . HIS A 1 547 ? 152.298 131.538 144.480 1.00 67.28  0  546 HIS A N   1 
ATOM   4309 C  CA  . HIS A 1 547 ? 151.994 130.957 143.177 1.00 67.28  0  546 HIS A CA  1 
ATOM   4310 C  C   . HIS A 1 547 ? 151.377 129.571 143.320 1.00 67.28  0  546 HIS A C   1 
ATOM   4311 O  O   . HIS A 1 547 ? 150.413 129.241 142.618 1.00 67.28  0  546 HIS A O   1 
ATOM   4312 C  CB  . HIS A 1 547 ? 153.255 130.905 142.317 1.00 67.28  0  546 HIS A CB  1 
ATOM   4313 C  CG  . HIS A 1 547 ? 153.577 132.202 141.643 1.00 67.28  0  546 HIS A CG  1 
ATOM   4314 N  ND1 . HIS A 1 547 ? 154.643 132.348 140.783 1.00 67.28  0  546 HIS A ND1 1 
ATOM   4315 C  CD2 . HIS A 1 547 ? 152.973 133.412 141.703 1.00 67.28  0  546 HIS A CD2 1 
ATOM   4316 C  CE1 . HIS A 1 547 ? 154.682 133.592 140.340 1.00 67.28  0  546 HIS A CE1 1 
ATOM   4317 N  NE2 . HIS A 1 547 ? 153.680 134.259 140.884 1.00 67.28  0  546 HIS A NE2 1 
ATOM   4318 N  N   . GLY A 1 548 ? 151.906 128.750 144.230 1.00 67.28  0  547 GLY A N   1 
ATOM   4319 C  CA  . GLY A 1 548 ? 151.295 127.453 144.477 1.00 67.28  0  547 GLY A CA  1 
ATOM   4320 C  C   . GLY A 1 548 ? 149.891 127.571 145.037 1.00 67.28  0  547 GLY A C   1 
ATOM   4321 O  O   . GLY A 1 548 ? 148.987 126.824 144.645 1.00 67.28  0  547 GLY A O   1 
ATOM   4322 N  N   . TYR A 1 549 ? 149.687 128.515 145.960 1.00 67.28  0  548 TYR A N   1 
ATOM   4323 C  CA  . TYR A 1 549 ? 148.354 128.732 146.510 1.00 67.28  0  548 TYR A CA  1 
ATOM   4324 C  C   . TYR A 1 549 ? 147.376 129.162 145.425 1.00 67.28  0  548 TYR A C   1 
ATOM   4325 O  O   . TYR A 1 549 ? 146.229 128.704 145.398 1.00 67.28  0  548 TYR A O   1 
ATOM   4326 C  CB  . TYR A 1 549 ? 148.408 129.781 147.619 1.00 67.28  0  548 TYR A CB  1 
ATOM   4327 C  CG  . TYR A 1 549 ? 149.040 129.303 148.904 1.00 67.28  0  548 TYR A CG  1 
ATOM   4328 C  CD1 . TYR A 1 549 ? 148.960 127.974 149.289 1.00 67.28  0  548 TYR A CD1 1 
ATOM   4329 C  CD2 . TYR A 1 549 ? 149.715 130.186 149.733 1.00 67.28  0  548 TYR A CD2 1 
ATOM   4330 C  CE1 . TYR A 1 549 ? 149.536 127.538 150.464 1.00 67.28  0  548 TYR A CE1 1 
ATOM   4331 C  CE2 . TYR A 1 549 ? 150.294 129.760 150.908 1.00 67.28  0  548 TYR A CE2 1 
ATOM   4332 C  CZ  . TYR A 1 549 ? 150.202 128.436 151.269 1.00 67.28  0  548 TYR A CZ  1 
ATOM   4333 O  OH  . TYR A 1 549 ? 150.779 128.009 152.442 1.00 67.28  0  548 TYR A OH  1 
ATOM   4334 N  N   . TYR A 1 550 ? 147.810 130.047 144.527 1.00 67.28  0  549 TYR A N   1 
ATOM   4335 C  CA  . TYR A 1 550 ? 146.955 130.486 143.430 1.00 67.28  0  549 TYR A CA  1 
ATOM   4336 C  C   . TYR A 1 550 ? 146.644 129.336 142.483 1.00 67.28  0  549 TYR A C   1 
ATOM   4337 O  O   . TYR A 1 550 ? 145.519 129.218 141.984 1.00 67.28  0  549 TYR A O   1 
ATOM   4338 C  CB  . TYR A 1 550 ? 147.625 131.635 142.677 1.00 67.28  0  549 TYR A CB  1 
ATOM   4339 C  CG  . TYR A 1 550 ? 146.663 132.659 142.123 1.00 67.28  0  549 TYR A CG  1 
ATOM   4340 C  CD1 . TYR A 1 550 ? 146.130 133.649 142.935 1.00 67.28  0  549 TYR A CD1 1 
ATOM   4341 C  CD2 . TYR A 1 550 ? 146.293 132.639 140.785 1.00 67.28  0  549 TYR A CD2 1 
ATOM   4342 C  CE1 . TYR A 1 550 ? 145.252 134.588 142.432 1.00 67.28  0  549 TYR A CE1 1 
ATOM   4343 C  CE2 . TYR A 1 550 ? 145.416 133.574 140.273 1.00 67.28  0  549 TYR A CE2 1 
ATOM   4344 C  CZ  . TYR A 1 550 ? 144.898 134.546 141.101 1.00 67.28  0  549 TYR A CZ  1 
ATOM   4345 O  OH  . TYR A 1 550 ? 144.023 135.480 140.596 1.00 67.28  0  549 TYR A OH  1 
ATOM   4346 N  N   . LYS A 1 551 ? 147.634 128.481 142.217 1.00 67.28  0  550 LYS A N   1 
ATOM   4347 C  CA  . LYS A 1 551 ? 147.406 127.331 141.350 1.00 67.28  0  550 LYS A CA  1 
ATOM   4348 C  C   . LYS A 1 551 ? 146.389 126.373 141.957 1.00 67.28  0  550 LYS A C   1 
ATOM   4349 O  O   . LYS A 1 551 ? 145.541 125.824 141.245 1.00 67.28  0  550 LYS A O   1 
ATOM   4350 C  CB  . LYS A 1 551 ? 148.725 126.609 141.079 1.00 67.28  0  550 LYS A CB  1 
ATOM   4351 C  CG  . LYS A 1 551 ? 148.616 125.476 140.074 1.00 67.28  0  550 LYS A CG  1 
ATOM   4352 C  CD  . LYS A 1 551 ? 149.949 124.771 139.889 1.00 67.28  0  550 LYS A CD  1 
ATOM   4353 C  CE  . LYS A 1 551 ? 151.005 125.715 139.344 1.00 67.28  0  550 LYS A CE  1 
ATOM   4354 N  NZ  . LYS A 1 551 ? 151.083 125.658 137.858 1.00 67.28  1  550 LYS A NZ  1 
ATOM   4355 N  N   . ILE A 1 552 ? 146.458 126.158 143.272 1.00 67.28  0  551 ILE A N   1 
ATOM   4356 C  CA  . ILE A 1 552 ? 145.574 125.178 143.900 1.00 67.28  0  551 ILE A CA  1 
ATOM   4357 C  C   . ILE A 1 552 ? 144.173 125.754 144.090 1.00 67.28  0  551 ILE A C   1 
ATOM   4358 O  O   . ILE A 1 552 ? 143.175 125.135 143.702 1.00 67.28  0  551 ILE A O   1 
ATOM   4359 C  CB  . ILE A 1 552 ? 146.174 124.688 145.229 1.00 67.28  0  551 ILE A CB  1 
ATOM   4360 C  CG1 . ILE A 1 552 ? 147.327 123.721 144.955 1.00 67.28  0  551 ILE A CG1 1 
ATOM   4361 C  CG2 . ILE A 1 552 ? 145.109 124.022 146.083 1.00 67.28  0  551 ILE A CG2 1 
ATOM   4362 C  CD1 . ILE A 1 552 ? 148.131 123.361 146.177 1.00 67.28  0  551 ILE A CD1 1 
ATOM   4363 N  N   . ASP A 1 553 ? 144.076 126.942 144.681 1.00 67.28  0  552 ASP A N   1 
ATOM   4364 C  CA  . ASP A 1 553 ? 142.781 127.567 144.945 1.00 67.28  0  552 ASP A CA  1 
ATOM   4365 C  C   . ASP A 1 553 ? 142.983 129.072 145.001 1.00 67.28  0  552 ASP A C   1 
ATOM   4366 O  O   . ASP A 1 553 ? 143.680 129.568 145.891 1.00 67.28  0  552 ASP A O   1 
ATOM   4367 C  CB  . ASP A 1 553 ? 142.180 127.048 146.253 1.00 67.28  0  552 ASP A CB  1 
ATOM   4368 C  CG  . ASP A 1 553 ? 140.748 127.508 146.467 1.00 67.28  0  552 ASP A CG  1 
ATOM   4369 O  OD1 . ASP A 1 553 ? 140.220 128.257 145.617 1.00 67.28  0  552 ASP A OD1 1 
ATOM   4370 O  OD2 . ASP A 1 553 ? 140.147 127.118 147.490 1.00 67.28  -1 552 ASP A OD2 1 
ATOM   4371 N  N   . ALA A 1 554 ? 142.367 129.795 144.063 1.00 67.28  0  553 ALA A N   1 
ATOM   4372 C  CA  . ALA A 1 554 ? 142.583 131.236 143.971 1.00 67.28  0  553 ALA A CA  1 
ATOM   4373 C  C   . ALA A 1 554 ? 142.060 131.965 145.203 1.00 67.28  0  553 ALA A C   1 
ATOM   4374 O  O   . ALA A 1 554 ? 142.668 132.942 145.656 1.00 67.28  0  553 ALA A O   1 
ATOM   4375 C  CB  . ALA A 1 554 ? 141.925 131.785 142.705 1.00 67.28  0  553 ALA A CB  1 
ATOM   4376 N  N   . GLU A 1 555 ? 140.935 131.509 145.759 1.00 67.28  0  554 GLU A N   1 
ATOM   4377 C  CA  . GLU A 1 555 ? 140.332 132.199 146.895 1.00 67.28  0  554 GLU A CA  1 
ATOM   4378 C  C   . GLU A 1 555 ? 141.201 132.142 148.145 1.00 67.28  0  554 GLU A C   1 
ATOM   4379 O  O   . GLU A 1 555 ? 140.967 132.916 149.079 1.00 67.28  0  554 GLU A O   1 
ATOM   4380 C  CB  . GLU A 1 555 ? 138.950 131.616 147.190 1.00 67.28  0  554 GLU A CB  1 
ATOM   4381 C  CG  . GLU A 1 555 ? 137.920 131.907 146.111 1.00 67.28  0  554 GLU A CG  1 
ATOM   4382 C  CD  . GLU A 1 555 ? 136.565 131.305 146.420 1.00 67.28  0  554 GLU A CD  1 
ATOM   4383 O  OE1 . GLU A 1 555 ? 136.460 130.549 147.408 1.00 67.28  0  554 GLU A OE1 1 
ATOM   4384 O  OE2 . GLU A 1 555 ? 135.603 131.590 145.676 1.00 67.28  -1 554 GLU A OE2 1 
ATOM   4385 N  N   . LEU A 1 556 ? 142.192 131.250 148.187 1.00 67.28  0  555 LEU A N   1 
ATOM   4386 C  CA  . LEU A 1 556 ? 143.136 131.242 149.297 1.00 67.28  0  555 LEU A CA  1 
ATOM   4387 C  C   . LEU A 1 556 ? 144.064 132.449 149.269 1.00 67.28  0  555 LEU A C   1 
ATOM   4388 O  O   . LEU A 1 556 ? 144.653 132.787 150.301 1.00 67.28  0  555 LEU A O   1 
ATOM   4389 C  CB  . LEU A 1 556 ? 143.959 129.953 149.279 1.00 67.28  0  555 LEU A CB  1 
ATOM   4390 C  CG  . LEU A 1 556 ? 143.286 128.700 149.841 1.00 67.28  0  555 LEU A CG  1 
ATOM   4391 C  CD1 . LEU A 1 556 ? 144.303 127.585 150.019 1.00 67.28  0  555 LEU A CD1 1 
ATOM   4392 C  CD2 . LEU A 1 556 ? 142.585 129.005 151.154 1.00 67.28  0  555 LEU A CD2 1 
ATOM   4393 N  N   . VAL A 1 557 ? 144.206 133.102 148.117 1.00 67.28  0  556 VAL A N   1 
ATOM   4394 C  CA  . VAL A 1 557 ? 145.060 134.270 147.973 1.00 67.28  0  556 VAL A CA  1 
ATOM   4395 C  C   . VAL A 1 557 ? 144.245 135.545 147.793 1.00 67.28  0  556 VAL A C   1 
ATOM   4396 O  O   . VAL A 1 557 ? 144.564 136.576 148.389 1.00 67.28  0  556 VAL A O   1 
ATOM   4397 C  CB  . VAL A 1 557 ? 146.048 134.078 146.802 1.00 67.28  0  556 VAL A CB  1 
ATOM   4398 C  CG1 . VAL A 1 557 ? 146.703 135.398 146.424 1.00 67.28  0  556 VAL A CG1 1 
ATOM   4399 C  CG2 . VAL A 1 557 ? 147.092 133.046 147.160 1.00 67.28  0  556 VAL A CG2 1 
ATOM   4400 N  N   . LEU A 1 558 ? 143.192 135.491 146.985 1.00 67.28  0  557 LEU A N   1 
ATOM   4401 C  CA  . LEU A 1 558 ? 142.407 136.683 146.703 1.00 67.28  0  557 LEU A CA  1 
ATOM   4402 C  C   . LEU A 1 558 ? 141.737 137.189 147.979 1.00 67.28  0  557 LEU A C   1 
ATOM   4403 O  O   . LEU A 1 558 ? 141.318 136.387 148.823 1.00 67.28  0  557 LEU A O   1 
ATOM   4404 C  CB  . LEU A 1 558 ? 141.353 136.385 145.636 1.00 67.28  0  557 LEU A CB  1 
ATOM   4405 C  CG  . LEU A 1 558 ? 141.874 136.227 144.207 1.00 67.28  0  557 LEU A CG  1 
ATOM   4406 C  CD1 . LEU A 1 558 ? 140.721 136.147 143.221 1.00 67.28  0  557 LEU A CD1 1 
ATOM   4407 C  CD2 . LEU A 1 558 ? 142.813 137.367 143.848 1.00 67.28  0  557 LEU A CD2 1 
ATOM   4408 N  N   . PRO A 1 559 ? 141.617 138.505 148.154 1.00 67.28  0  558 PRO A N   1 
ATOM   4409 C  CA  . PRO A 1 559 ? 141.036 139.076 149.388 1.00 67.28  0  558 PRO A CA  1 
ATOM   4410 C  C   . PRO A 1 559 ? 139.515 139.186 149.333 1.00 67.28  0  558 PRO A C   1 
ATOM   4411 O  O   . PRO A 1 559 ? 138.925 140.276 149.349 1.00 67.28  0  558 PRO A O   1 
ATOM   4412 C  CB  . PRO A 1 559 ? 141.721 140.442 149.461 1.00 67.28  0  558 PRO A CB  1 
ATOM   4413 C  CG  . PRO A 1 559 ? 141.915 140.826 148.031 1.00 67.28  0  558 PRO A CG  1 
ATOM   4414 C  CD  . PRO A 1 559 ? 142.103 139.553 147.240 1.00 67.28  0  558 PRO A CD  1 
ATOM   4415 N  N   . THR A 1 560 ? 138.853 138.034 149.266 1.00 67.28  0  559 THR A N   1 
ATOM   4416 C  CA  . THR A 1 560 ? 137.398 137.955 149.262 1.00 67.28  0  559 THR A CA  1 
ATOM   4417 C  C   . THR A 1 560 ? 136.848 137.261 150.498 1.00 67.28  0  559 THR A C   1 
ATOM   4418 O  O   . THR A 1 560 ? 135.974 137.806 151.185 1.00 67.28  0  559 THR A O   1 
ATOM   4419 C  CB  . THR A 1 560 ? 136.914 137.225 148.000 1.00 67.28  0  559 THR A CB  1 
ATOM   4420 O  OG1 . THR A 1 560 ? 137.273 137.983 146.839 1.00 67.28  0  559 THR A OG1 1 
ATOM   4421 C  CG2 . THR A 1 560 ? 135.406 137.042 148.034 1.00 67.28  0  559 THR A CG2 1 
ATOM   4422 N  N   . ILE A 1 561 ? 137.347 136.059 150.795 1.00 67.28  0  560 ILE A N   1 
ATOM   4423 C  CA  . ILE A 1 561 ? 136.885 135.327 151.970 1.00 67.28  0  560 ILE A CA  1 
ATOM   4424 C  C   . ILE A 1 561 ? 137.227 136.090 153.241 1.00 67.28  0  560 ILE A C   1 
ATOM   4425 O  O   . ILE A 1 561 ? 136.408 136.187 154.161 1.00 67.28  0  560 ILE A O   1 
ATOM   4426 C  CB  . ILE A 1 561 ? 137.483 133.910 151.984 1.00 67.28  0  560 ILE A CB  1 
ATOM   4427 C  CG1 . ILE A 1 561 ? 137.132 133.177 150.690 1.00 67.28  0  560 ILE A CG1 1 
ATOM   4428 C  CG2 . ILE A 1 561 ? 136.980 133.134 153.190 1.00 67.28  0  560 ILE A CG2 1 
ATOM   4429 C  CD1 . ILE A 1 561 ? 137.474 131.714 150.717 1.00 67.28  0  560 ILE A CD1 1 
ATOM   4430 N  N   . ARG A 1 562 ? 138.442 136.638 153.316 1.00 67.28  0  561 ARG A N   1 
ATOM   4431 C  CA  . ARG A 1 562 ? 138.827 137.407 154.494 1.00 67.28  0  561 ARG A CA  1 
ATOM   4432 C  C   . ARG A 1 562 ? 137.987 138.668 154.635 1.00 67.28  0  561 ARG A C   1 
ATOM   4433 O  O   . ARG A 1 562 ? 137.615 139.048 155.750 1.00 67.28  0  561 ARG A O   1 
ATOM   4434 C  CB  . ARG A 1 562 ? 140.313 137.756 154.443 1.00 67.28  0  561 ARG A CB  1 
ATOM   4435 C  CG  . ARG A 1 562 ? 140.846 138.284 155.763 1.00 67.28  0  561 ARG A CG  1 
ATOM   4436 C  CD  . ARG A 1 562 ? 140.428 137.386 156.916 1.00 67.28  0  561 ARG A CD  1 
ATOM   4437 N  NE  . ARG A 1 562 ? 141.040 137.784 158.177 1.00 67.28  0  561 ARG A NE  1 
ATOM   4438 C  CZ  . ARG A 1 562 ? 140.893 137.128 159.320 1.00 67.28  0  561 ARG A CZ  1 
ATOM   4439 N  NH1 . ARG A 1 562 ? 140.154 136.033 159.398 1.00 67.28  1  561 ARG A NH1 1 
ATOM   4440 N  NH2 . ARG A 1 562 ? 141.500 137.582 160.412 1.00 67.28  0  561 ARG A NH2 1 
ATOM   4441 N  N   . SER A 1 563 ? 137.684 139.336 153.519 1.00 67.28  0  562 SER A N   1 
ATOM   4442 C  CA  . SER A 1 563 ? 136.830 140.518 153.581 1.00 67.28  0  562 SER A CA  1 
ATOM   4443 C  C   . SER A 1 563 ? 135.440 140.167 154.098 1.00 67.28  0  562 SER A C   1 
ATOM   4444 O  O   . SER A 1 563 ? 134.891 140.870 154.957 1.00 67.28  0  562 SER A O   1 
ATOM   4445 C  CB  . SER A 1 563 ? 136.739 141.172 152.203 1.00 67.28  0  562 SER A CB  1 
ATOM   4446 O  OG  . SER A 1 563 ? 135.741 142.178 152.185 1.00 67.28  0  562 SER A OG  1 
ATOM   4447 N  N   . ALA A 1 564 ? 134.861 139.073 153.596 1.00 67.28  0  563 ALA A N   1 
ATOM   4448 C  CA  . ALA A 1 564 ? 133.548 138.649 154.074 1.00 67.28  0  563 ALA A CA  1 
ATOM   4449 C  C   . ALA A 1 564 ? 133.591 138.270 155.550 1.00 67.28  0  563 ALA A C   1 
ATOM   4450 O  O   . ALA A 1 564 ? 132.673 138.599 156.313 1.00 67.28  0  563 ALA A O   1 
ATOM   4451 C  CB  . ALA A 1 564 ? 133.035 137.482 153.232 1.00 67.28  0  563 ALA A CB  1 
ATOM   4452 N  N   . VAL A 1 565 ? 134.652 137.578 155.971 1.00 67.28  0  564 VAL A N   1 
ATOM   4453 C  CA  . VAL A 1 565 ? 134.773 137.165 157.366 1.00 67.28  0  564 VAL A CA  1 
ATOM   4454 C  C   . VAL A 1 565 ? 134.897 138.380 158.274 1.00 67.28  0  564 VAL A C   1 
ATOM   4455 O  O   . VAL A 1 565 ? 134.285 138.438 159.346 1.00 67.28  0  564 VAL A O   1 
ATOM   4456 C  CB  . VAL A 1 565 ? 135.965 136.205 157.533 1.00 67.28  0  564 VAL A CB  1 
ATOM   4457 C  CG1 . VAL A 1 565 ? 136.383 136.116 158.993 1.00 67.28  0  564 VAL A CG1 1 
ATOM   4458 C  CG2 . VAL A 1 565 ? 135.613 134.834 156.990 1.00 67.28  0  564 VAL A CG2 1 
ATOM   4459 N  N   . GLU A 1 566 ? 135.688 139.371 157.862 1.00 67.28  0  565 GLU A N   1 
ATOM   4460 C  CA  . GLU A 1 566 ? 135.844 140.570 158.676 1.00 67.28  0  565 GLU A CA  1 
ATOM   4461 C  C   . GLU A 1 566 ? 134.549 141.369 158.730 1.00 67.28  0  565 GLU A C   1 
ATOM   4462 O  O   . GLU A 1 566 ? 134.217 141.955 159.768 1.00 67.28  0  565 GLU A O   1 
ATOM   4463 C  CB  . GLU A 1 566 ? 136.993 141.419 158.137 1.00 67.28  0  565 GLU A CB  1 
ATOM   4464 C  CG  . GLU A 1 566 ? 138.359 140.938 158.592 1.00 67.28  0  565 GLU A CG  1 
ATOM   4465 C  CD  . GLU A 1 566 ? 139.396 142.039 158.601 1.00 67.28  0  565 GLU A CD  1 
ATOM   4466 O  OE1 . GLU A 1 566 ? 139.956 142.338 157.527 1.00 67.28  0  565 GLU A OE1 1 
ATOM   4467 O  OE2 . GLU A 1 566 ? 139.662 142.595 159.685 1.00 67.28  -1 565 GLU A OE2 1 
ATOM   4468 N  N   . LYS A 1 567 ? 133.797 141.402 157.625 1.00 67.28  0  566 LYS A N   1 
ATOM   4469 C  CA  . LYS A 1 567 ? 132.487 142.043 157.662 1.00 67.28  0  566 LYS A CA  1 
ATOM   4470 C  C   . LYS A 1 567 ? 131.565 141.339 158.649 1.00 67.28  0  566 LYS A C   1 
ATOM   4471 O  O   . LYS A 1 567 ? 130.880 141.990 159.449 1.00 67.28  0  566 LYS A O   1 
ATOM   4472 C  CB  . LYS A 1 567 ? 131.867 142.059 156.263 1.00 67.28  0  566 LYS A CB  1 
ATOM   4473 C  CG  . LYS A 1 567 ? 132.355 143.198 155.377 1.00 67.28  0  566 LYS A CG  1 
ATOM   4474 C  CD  . LYS A 1 567 ? 131.596 143.238 154.058 1.00 67.28  0  566 LYS A CD  1 
ATOM   4475 C  CE  . LYS A 1 567 ? 132.057 144.391 153.186 1.00 67.28  0  566 LYS A CE  1 
ATOM   4476 N  NZ  . LYS A 1 567 ? 133.458 144.200 152.729 1.00 67.28  1  566 LYS A NZ  1 
ATOM   4477 N  N   . GLN A 1 568 ? 131.550 140.004 158.625 1.00 67.28  0  567 GLN A N   1 
ATOM   4478 C  CA  . GLN A 1 568 ? 130.704 139.271 159.560 1.00 67.28  0  567 GLN A CA  1 
ATOM   4479 C  C   . GLN A 1 568 ? 131.155 139.478 161.000 1.00 67.28  0  567 GLN A C   1 
ATOM   4480 O  O   . GLN A 1 568 ? 130.321 139.515 161.909 1.00 67.28  0  567 GLN A O   1 
ATOM   4481 C  CB  . GLN A 1 568 ? 130.687 137.785 159.205 1.00 67.28  0  567 GLN A CB  1 
ATOM   4482 C  CG  . GLN A 1 568 ? 129.810 137.468 158.008 1.00 67.28  0  567 GLN A CG  1 
ATOM   4483 C  CD  . GLN A 1 568 ? 128.332 137.483 158.344 1.00 67.28  0  567 GLN A CD  1 
ATOM   4484 O  OE1 . GLN A 1 568 ? 127.898 136.875 159.322 1.00 67.28  0  567 GLN A OE1 1 
ATOM   4485 N  NE2 . GLN A 1 568 ? 127.551 138.194 157.539 1.00 67.28  0  567 GLN A NE2 1 
ATOM   4486 N  N   . LEU A 1 569 ? 132.460 139.636 161.226 1.00 67.28  0  568 LEU A N   1 
ATOM   4487 C  CA  . LEU A 1 569 ? 132.943 139.972 162.563 1.00 67.28  0  568 LEU A CA  1 
ATOM   4488 C  C   . LEU A 1 569 ? 132.476 141.361 162.986 1.00 67.28  0  568 LEU A C   1 
ATOM   4489 O  O   . LEU A 1 569 ? 132.157 141.587 164.160 1.00 67.28  0  568 LEU A O   1 
ATOM   4490 C  CB  . LEU A 1 569 ? 134.467 139.879 162.614 1.00 67.28  0  568 LEU A CB  1 
ATOM   4491 C  CG  . LEU A 1 569 ? 135.086 138.491 162.447 1.00 67.28  0  568 LEU A CG  1 
ATOM   4492 C  CD1 . LEU A 1 569 ? 136.528 138.598 161.974 1.00 67.28  0  568 LEU A CD1 1 
ATOM   4493 C  CD2 . LEU A 1 569 ? 134.998 137.705 163.744 1.00 67.28  0  568 LEU A CD2 1 
ATOM   4494 N  N   . ASN A 1 570 ? 132.440 142.308 162.048 1.00 67.28  0  569 ASN A N   1 
ATOM   4495 C  CA  . ASN A 1 570 ? 131.917 143.633 162.366 1.00 67.28  0  569 ASN A CA  1 
ATOM   4496 C  C   . ASN A 1 570 ? 130.441 143.558 162.752 1.00 67.28  0  569 ASN A C   1 
ATOM   4497 O  O   . ASN A 1 570 ? 130.007 144.209 163.710 1.00 67.28  0  569 ASN A O   1 
ATOM   4498 C  CB  . ASN A 1 570 ? 132.123 144.572 161.177 1.00 67.28  0  569 ASN A CB  1 
ATOM   4499 C  CG  . ASN A 1 570 ? 131.799 146.016 161.504 1.00 67.28  0  569 ASN A CG  1 
ATOM   4500 O  OD1 . ASN A 1 570 ? 131.390 146.340 162.618 1.00 67.28  0  569 ASN A OD1 1 
ATOM   4501 N  ND2 . ASN A 1 570 ? 131.987 146.896 160.529 1.00 67.28  0  569 ASN A ND2 1 
ATOM   4502 N  N   . LEU A 1 571 ? 129.656 142.761 162.021 1.00 67.28  0  570 LEU A N   1 
ATOM   4503 C  CA  . LEU A 1 571 ? 128.261 142.552 162.414 1.00 67.28  0  570 LEU A CA  1 
ATOM   4504 C  C   . LEU A 1 571 ? 128.141 141.822 163.749 1.00 67.28  0  570 LEU A C   1 
ATOM   4505 O  O   . LEU A 1 571 ? 127.171 142.043 164.484 1.00 67.28  0  570 LEU A O   1 
ATOM   4506 C  CB  . LEU A 1 571 ? 127.481 141.808 161.328 1.00 67.28  0  570 LEU A CB  1 
ATOM   4507 C  CG  . LEU A 1 571 ? 126.992 142.571 160.086 1.00 67.28  0  570 LEU A CG  1 
ATOM   4508 C  CD1 . LEU A 1 571 ? 128.074 142.981 159.106 1.00 67.28  0  570 LEU A CD1 1 
ATOM   4509 C  CD2 . LEU A 1 571 ? 125.914 141.767 159.377 1.00 67.28  0  570 LEU A CD2 1 
ATOM   4510 N  N   . ILE A 1 572 ? 129.093 140.944 164.073 1.00 67.28  0  571 ILE A N   1 
ATOM   4511 C  CA  . ILE A 1 572 ? 129.151 140.379 165.420 1.00 67.28  0  571 ILE A CA  1 
ATOM   4512 C  C   . ILE A 1 572 ? 129.307 141.497 166.439 1.00 67.28  0  571 ILE A C   1 
ATOM   4513 O  O   . ILE A 1 572 ? 128.626 141.530 167.471 1.00 67.28  0  571 ILE A O   1 
ATOM   4514 C  CB  . ILE A 1 572 ? 130.304 139.366 165.540 1.00 67.28  0  571 ILE A CB  1 
ATOM   4515 C  CG1 . ILE A 1 572 ? 130.030 138.107 164.724 1.00 67.28  0  571 ILE A CG1 1 
ATOM   4516 C  CG2 . ILE A 1 572 ? 130.546 139.004 167.000 1.00 67.28  0  571 ILE A CG2 1 
ATOM   4517 C  CD1 . ILE A 1 572 ? 131.153 137.108 164.803 1.00 67.28  0  571 ILE A CD1 1 
ATOM   4518 N  N   . ALA A 1 573 ? 130.211 142.434 166.151 1.00 67.28  0  572 ALA A N   1 
ATOM   4519 C  CA  . ALA A 1 573 ? 130.450 143.550 167.059 1.00 67.28  0  572 ALA A CA  1 
ATOM   4520 C  C   . ALA A 1 573 ? 129.197 144.397 167.239 1.00 67.28  0  572 ALA A C   1 
ATOM   4521 O  O   . ALA A 1 573 ? 128.872 144.805 168.360 1.00 67.28  0  572 ALA A O   1 
ATOM   4522 C  CB  . ALA A 1 573 ? 131.607 144.408 166.547 1.00 67.28  0  572 ALA A CB  1 
ATOM   4523 N  N   . GLN A 1 574 ? 128.479 144.673 166.153 1.00 67.28  0  573 GLN A N   1 
ATOM   4524 C  CA  . GLN A 1 574 ? 127.270 145.492 166.247 1.00 67.28  0  573 GLN A CA  1 
ATOM   4525 C  C   . GLN A 1 574 ? 126.022 144.640 166.460 1.00 67.28  0  573 GLN A C   1 
ATOM   4526 O  O   . GLN A 1 574 ? 124.997 144.828 165.810 1.00 67.28  0  573 GLN A O   1 
ATOM   4527 C  CB  . GLN A 1 574 ? 127.126 146.356 165.000 1.00 67.28  0  573 GLN A CB  1 
ATOM   4528 C  CG  . GLN A 1 574 ? 128.425 146.942 164.484 1.00 67.28  0  573 GLN A CG  1 
ATOM   4529 C  CD  . GLN A 1 574 ? 128.267 147.573 163.115 1.00 67.28  0  573 GLN A CD  1 
ATOM   4530 O  OE1 . GLN A 1 574 ? 127.160 147.664 162.586 1.00 67.28  0  573 GLN A OE1 1 
ATOM   4531 N  NE2 . GLN A 1 574 ? 129.377 148.011 162.534 1.00 67.28  0  573 GLN A NE2 1 
ATOM   4532 N  N   . GLY A 1 575 ? 126.103 143.711 167.408 1.00 67.28  0  574 GLY A N   1 
ATOM   4533 C  CA  . GLY A 1 575 ? 124.960 142.965 167.902 1.00 67.28  0  574 GLY A CA  1 
ATOM   4534 C  C   . GLY A 1 575 ? 124.022 142.289 166.919 1.00 67.28  0  574 GLY A C   1 
ATOM   4535 O  O   . GLY A 1 575 ? 122.941 141.854 167.327 1.00 67.28  0  574 GLY A O   1 
ATOM   4536 N  N   . LYS A 1 576 ? 124.389 142.178 165.636 1.00 67.28  0  575 LYS A N   1 
ATOM   4537 C  CA  . LYS A 1 576 ? 123.543 141.484 164.657 1.00 67.28  0  575 LYS A CA  1 
ATOM   4538 C  C   . LYS A 1 576 ? 124.394 140.470 163.893 1.00 67.28  0  575 LYS A C   1 
ATOM   4539 O  O   . LYS A 1 576 ? 124.831 140.727 162.770 1.00 67.28  0  575 LYS A O   1 
ATOM   4540 C  CB  . LYS A 1 576 ? 122.860 142.482 163.711 1.00 67.28  0  575 LYS A CB  1 
ATOM   4541 C  CG  . LYS A 1 576 ? 123.748 143.625 163.243 1.00 67.28  0  575 LYS A CG  1 
ATOM   4542 C  CD  . LYS A 1 576 ? 122.925 144.817 162.784 1.00 67.28  0  575 LYS A CD  1 
ATOM   4543 C  CE  . LYS A 1 576 ? 123.789 146.059 162.650 1.00 67.28  0  575 LYS A CE  1 
ATOM   4544 N  NZ  . LYS A 1 576 ? 122.968 147.293 162.524 1.00 67.28  1  575 LYS A NZ  1 
ATOM   4545 N  N   . ALA A 1 577 ? 124.587 139.303 164.503 1.00 67.28  0  576 ALA A N   1 
ATOM   4546 C  CA  . ALA A 1 577 ? 125.262 138.147 163.925 1.00 67.28  0  576 ALA A CA  1 
ATOM   4547 C  C   . ALA A 1 577 ? 125.256 137.048 164.975 1.00 67.28  0  576 ALA A C   1 
ATOM   4548 O  O   . ALA A 1 577 ? 125.062 137.312 166.165 1.00 67.28  0  576 ALA A O   1 
ATOM   4549 C  CB  . ALA A 1 577 ? 126.697 138.456 163.489 1.00 67.28  0  576 ALA A CB  1 
ATOM   4550 N  N   . ASP A 1 578 ? 125.472 135.817 164.528 1.00 68.20  0  577 ASP A N   1 
ATOM   4551 C  CA  . ASP A 1 578 ? 125.607 134.679 165.427 1.00 68.20  0  577 ASP A CA  1 
ATOM   4552 C  C   . ASP A 1 578 ? 127.050 134.198 165.387 1.00 68.20  0  577 ASP A C   1 
ATOM   4553 O  O   . ASP A 1 578 ? 127.535 133.757 164.337 1.00 68.20  0  577 ASP A O   1 
ATOM   4554 C  CB  . ASP A 1 578 ? 124.642 133.555 165.050 1.00 68.20  0  577 ASP A CB  1 
ATOM   4555 C  CG  . ASP A 1 578 ? 124.465 132.543 166.168 1.00 68.20  0  577 ASP A CG  1 
ATOM   4556 O  OD1 . ASP A 1 578 ? 125.115 132.701 167.223 1.00 68.20  0  577 ASP A OD1 1 
ATOM   4557 O  OD2 . ASP A 1 578 ? 123.666 131.599 166.001 1.00 68.20  -1 577 ASP A OD2 1 
ATOM   4558 N  N   . TYR A 1 579 ? 127.727 134.286 166.534 1.00 67.43  0  578 TYR A N   1 
ATOM   4559 C  CA  . TYR A 1 579 ? 129.133 133.902 166.619 1.00 67.43  0  578 TYR A CA  1 
ATOM   4560 C  C   . TYR A 1 579 ? 129.323 132.433 166.261 1.00 67.43  0  578 TYR A C   1 
ATOM   4561 O  O   . TYR A 1 579 ? 130.202 132.085 165.461 1.00 67.43  0  578 TYR A O   1 
ATOM   4562 C  CB  . TYR A 1 579 ? 129.649 134.207 168.028 1.00 67.43  0  578 TYR A CB  1 
ATOM   4563 C  CG  . TYR A 1 579 ? 130.843 133.402 168.493 1.00 67.43  0  578 TYR A CG  1 
ATOM   4564 C  CD1 . TYR A 1 579 ? 132.032 133.396 167.779 1.00 67.43  0  578 TYR A CD1 1 
ATOM   4565 C  CD2 . TYR A 1 579 ? 130.783 132.665 169.669 1.00 67.43  0  578 TYR A CD2 1 
ATOM   4566 C  CE1 . TYR A 1 579 ? 133.122 132.663 168.215 1.00 67.43  0  578 TYR A CE1 1 
ATOM   4567 C  CE2 . TYR A 1 579 ? 131.866 131.933 170.112 1.00 67.43  0  578 TYR A CE2 1 
ATOM   4568 C  CZ  . TYR A 1 579 ? 133.032 131.936 169.382 1.00 67.43  0  578 TYR A CZ  1 
ATOM   4569 O  OH  . TYR A 1 579 ? 134.114 131.206 169.820 1.00 67.43  0  578 TYR A OH  1 
ATOM   4570 N  N   . ARG A 1 580 ? 128.487 131.559 166.825 1.00 69.12  0  579 ARG A N   1 
ATOM   4571 C  CA  . ARG A 1 580 ? 128.582 130.137 166.515 1.00 69.12  0  579 ARG A CA  1 
ATOM   4572 C  C   . ARG A 1 580 ? 128.333 129.878 165.035 1.00 69.12  0  579 ARG A C   1 
ATOM   4573 O  O   . ARG A 1 580 ? 129.059 129.102 164.403 1.00 69.12  0  579 ARG A O   1 
ATOM   4574 C  CB  . ARG A 1 580 ? 127.594 129.347 167.371 1.00 69.12  0  579 ARG A CB  1 
ATOM   4575 C  CG  . ARG A 1 580 ? 127.997 129.209 168.830 1.00 69.12  0  579 ARG A CG  1 
ATOM   4576 C  CD  . ARG A 1 580 ? 128.922 128.021 169.041 1.00 69.12  0  579 ARG A CD  1 
ATOM   4577 N  NE  . ARG A 1 580 ? 129.780 128.195 170.208 1.00 69.12  0  579 ARG A NE  1 
ATOM   4578 C  CZ  . ARG A 1 580 ? 131.053 127.830 170.264 1.00 69.12  0  579 ARG A CZ  1 
ATOM   4579 N  NH1 . ARG A 1 580 ? 131.656 127.262 169.233 1.00 69.12  1  579 ARG A NH1 1 
ATOM   4580 N  NH2 . ARG A 1 580 ? 131.738 128.037 171.385 1.00 69.12  0  579 ARG A NH2 1 
ATOM   4581 N  N   . GLN A 1 581 ? 127.317 130.529 164.463 1.00 67.86  0  580 GLN A N   1 
ATOM   4582 C  CA  . GLN A 1 581 ? 126.981 130.298 163.061 1.00 67.86  0  580 GLN A CA  1 
ATOM   4583 C  C   . GLN A 1 581 ? 128.121 130.716 162.141 1.00 67.86  0  580 GLN A C   1 
ATOM   4584 O  O   . GLN A 1 581 ? 128.524 129.957 161.251 1.00 67.86  0  580 GLN A O   1 
ATOM   4585 C  CB  . GLN A 1 581 ? 125.699 131.046 162.696 1.00 67.86  0  580 GLN A CB  1 
ATOM   4586 C  CG  . GLN A 1 581 ? 124.427 130.383 163.195 1.00 67.86  0  580 GLN A CG  1 
ATOM   4587 C  CD  . GLN A 1 581 ? 124.197 129.020 162.574 1.00 67.86  0  580 GLN A CD  1 
ATOM   4588 O  OE1 . GLN A 1 581 ? 124.314 127.993 163.243 1.00 67.86  0  580 GLN A OE1 1 
ATOM   4589 N  NE2 . GLN A 1 581 ? 123.865 129.004 161.288 1.00 67.86  0  580 GLN A NE2 1 
ATOM   4590 N  N   . VAL A 1 582 ? 128.660 131.922 162.341 1.00 67.28  0  581 VAL A N   1 
ATOM   4591 C  CA  . VAL A 1 582 ? 129.719 132.396 161.455 1.00 67.28  0  581 VAL A CA  1 
ATOM   4592 C  C   . VAL A 1 582 ? 130.983 131.563 161.634 1.00 67.28  0  581 VAL A C   1 
ATOM   4593 O  O   . VAL A 1 582 ? 131.657 131.218 160.652 1.00 67.28  0  581 VAL A O   1 
ATOM   4594 C  CB  . VAL A 1 582 ? 129.982 133.898 161.672 1.00 67.28  0  581 VAL A CB  1 
ATOM   4595 C  CG1 . VAL A 1 582 ? 131.156 134.366 160.848 1.00 67.28  0  581 VAL A CG1 1 
ATOM   4596 C  CG2 . VAL A 1 582 ? 128.740 134.710 161.336 1.00 67.28  0  581 VAL A CG2 1 
ATOM   4597 N  N   . LEU A 1 583 ? 131.319 131.210 162.880 1.00 67.28  0  582 LEU A N   1 
ATOM   4598 C  CA  . LEU A 1 583 ? 132.505 130.397 163.118 1.00 67.28  0  582 LEU A CA  1 
ATOM   4599 C  C   . LEU A 1 583 ? 132.374 129.039 162.443 1.00 67.28  0  582 LEU A C   1 
ATOM   4600 O  O   . LEU A 1 583 ? 133.298 128.579 161.763 1.00 67.28  0  582 LEU A O   1 
ATOM   4601 C  CB  . LEU A 1 583 ? 132.731 130.239 164.621 1.00 67.28  0  582 LEU A CB  1 
ATOM   4602 C  CG  . LEU A 1 583 ? 134.159 129.958 165.088 1.00 67.28  0  582 LEU A CG  1 
ATOM   4603 C  CD1 . LEU A 1 583 ? 135.040 131.171 164.853 1.00 67.28  0  582 LEU A CD1 1 
ATOM   4604 C  CD2 . LEU A 1 583 ? 134.171 129.559 166.554 1.00 67.28  0  582 LEU A CD2 1 
ATOM   4605 N  N   . GLY A 1 584 ? 131.214 128.394 162.594 1.00 67.28  0  583 GLY A N   1 
ATOM   4606 C  CA  . GLY A 1 584 ? 131.012 127.100 161.969 1.00 67.28  0  583 GLY A CA  1 
ATOM   4607 C  C   . GLY A 1 584 ? 131.032 127.171 160.455 1.00 67.28  0  583 GLY A C   1 
ATOM   4608 O  O   . GLY A 1 584 ? 131.604 126.303 159.794 1.00 67.28  0  583 GLY A O   1 
ATOM   4609 N  N   . HIS A 1 585 ? 130.396 128.206 159.899 1.00 67.28  0  584 HIS A N   1 
ATOM   4610 C  CA  . HIS A 1 585 ? 130.370 128.375 158.423 1.00 67.28  0  584 HIS A CA  1 
ATOM   4611 C  C   . HIS A 1 585 ? 131.803 128.512 157.907 1.00 67.28  0  584 HIS A C   1 
ATOM   4612 O  O   . HIS A 1 585 ? 132.170 127.758 156.984 1.00 67.28  0  584 HIS A O   1 
ATOM   4613 C  CB  . HIS A 1 585 ? 129.507 129.575 158.019 1.00 67.28  0  584 HIS A CB  1 
ATOM   4614 C  CG  . HIS A 1 585 ? 129.541 129.875 156.558 1.00 67.28  0  584 HIS A CG  1 
ATOM   4615 N  ND1 . HIS A 1 585 ? 130.645 130.431 155.943 1.00 67.28  0  584 HIS A ND1 1 
ATOM   4616 C  CD2 . HIS A 1 585 ? 128.614 129.704 155.591 1.00 67.28  0  584 HIS A CD2 1 
ATOM   4617 C  CE1 . HIS A 1 585 ? 130.397 130.588 154.658 1.00 67.28  0  584 HIS A CE1 1 
ATOM   4618 N  NE2 . HIS A 1 585 ? 129.157 130.150 154.418 1.00 67.28  0  584 HIS A NE2 1 
ATOM   4619 N  N   . THR A 1 586 ? 132.578 129.432 158.485 1.00 67.28  0  585 THR A N   1 
ATOM   4620 C  CA  . THR A 1 586 ? 133.940 129.657 158.015 1.00 67.28  0  585 THR A CA  1 
ATOM   4621 C  C   . THR A 1 586 ? 134.795 128.409 158.190 1.00 67.28  0  585 THR A C   1 
ATOM   4622 O  O   . THR A 1 586 ? 135.575 128.049 157.297 1.00 67.28  0  585 THR A O   1 
ATOM   4623 C  CB  . THR A 1 586 ? 134.566 130.841 158.750 1.00 67.28  0  585 THR A CB  1 
ATOM   4624 O  OG1 . THR A 1 586 ? 133.634 131.927 158.790 1.00 67.28  0  585 THR A OG1 1 
ATOM   4625 C  CG2 . THR A 1 586 ? 135.830 131.295 158.040 1.00 67.28  0  585 THR A CG2 1 
ATOM   4626 N  N   . LEU A 1 587 ? 134.653 127.725 159.328 1.00 67.28  0  586 LEU A N   1 
ATOM   4627 C  CA  . LEU A 1 587 ? 135.428 126.513 159.553 1.00 67.28  0  586 LEU A CA  1 
ATOM   4628 C  C   . LEU A 1 587 ? 135.061 125.432 158.547 1.00 67.28  0  586 LEU A C   1 
ATOM   4629 O  O   . LEU A 1 587 ? 135.936 124.710 158.062 1.00 67.28  0  586 LEU A O   1 
ATOM   4630 C  CB  . LEU A 1 587 ? 135.226 126.018 160.983 1.00 67.28  0  586 LEU A CB  1 
ATOM   4631 C  CG  . LEU A 1 587 ? 135.949 126.837 162.054 1.00 67.28  0  586 LEU A CG  1 
ATOM   4632 C  CD1 . LEU A 1 587 ? 135.689 126.266 163.439 1.00 67.28  0  586 LEU A CD1 1 
ATOM   4633 C  CD2 . LEU A 1 587 ? 137.438 126.906 161.765 1.00 67.28  0  586 LEU A CD2 1 
ATOM   4634 N  N   . ASP A 1 588 ? 133.778 125.322 158.196 1.00 67.28  0  587 ASP A N   1 
ATOM   4635 C  CA  . ASP A 1 588 ? 133.354 124.300 157.245 1.00 67.28  0  587 ASP A CA  1 
ATOM   4636 C  C   . ASP A 1 588 ? 133.888 124.587 155.845 1.00 67.28  0  587 ASP A C   1 
ATOM   4637 O  O   . ASP A 1 588 ? 134.400 123.683 155.167 1.00 67.28  0  587 ASP A O   1 
ATOM   4638 C  CB  . ASP A 1 588 ? 131.829 124.203 157.231 1.00 67.28  0  587 ASP A CB  1 
ATOM   4639 C  CG  . ASP A 1 588 ? 131.337 122.821 156.855 1.00 67.28  0  587 ASP A CG  1 
ATOM   4640 O  OD1 . ASP A 1 588 ? 132.181 121.926 156.644 1.00 67.28  0  587 ASP A OD1 1 
ATOM   4641 O  OD2 . ASP A 1 588 ? 130.106 122.629 156.773 1.00 67.28  -1 587 ASP A OD2 1 
ATOM   4642 N  N   . VAL A 1 589 ? 133.777 125.839 155.389 1.00 67.28  0  588 VAL A N   1 
ATOM   4643 C  CA  . VAL A 1 589 ? 134.262 126.150 154.045 1.00 67.28  0  588 VAL A CA  1 
ATOM   4644 C  C   . VAL A 1 589 ? 135.776 125.978 153.975 1.00 67.28  0  588 VAL A C   1 
ATOM   4645 O  O   . VAL A 1 589 ? 136.310 125.429 152.999 1.00 67.28  0  588 VAL A O   1 
ATOM   4646 C  CB  . VAL A 1 589 ? 133.817 127.559 153.600 1.00 67.28  0  588 VAL A CB  1 
ATOM   4647 C  CG1 . VAL A 1 589 ? 134.259 128.622 154.579 1.00 67.28  0  588 VAL A CG1 1 
ATOM   4648 C  CG2 . VAL A 1 589 ? 134.342 127.866 152.206 1.00 67.28  0  588 VAL A CG2 1 
ATOM   4649 N  N   . PHE A 1 590 ? 136.494 126.403 155.020 1.00 67.28  0  589 PHE A N   1 
ATOM   4650 C  CA  . PHE A 1 590 ? 137.942 126.236 155.002 1.00 67.28  0  589 PHE A CA  1 
ATOM   4651 C  C   . PHE A 1 590 ? 138.346 124.778 155.177 1.00 67.28  0  589 PHE A C   1 
ATOM   4652 O  O   . PHE A 1 590 ? 139.400 124.373 154.685 1.00 67.28  0  589 PHE A O   1 
ATOM   4653 C  CB  . PHE A 1 590 ? 138.588 127.115 156.070 1.00 67.28  0  589 PHE A CB  1 
ATOM   4654 C  CG  . PHE A 1 590 ? 138.951 128.485 155.576 1.00 67.28  0  589 PHE A CG  1 
ATOM   4655 C  CD1 . PHE A 1 590 ? 140.054 128.671 154.762 1.00 67.28  0  589 PHE A CD1 1 
ATOM   4656 C  CD2 . PHE A 1 590 ? 138.179 129.584 155.910 1.00 67.28  0  589 PHE A CD2 1 
ATOM   4657 C  CE1 . PHE A 1 590 ? 140.388 129.928 154.302 1.00 67.28  0  589 PHE A CE1 1 
ATOM   4658 C  CE2 . PHE A 1 590 ? 138.509 130.843 155.453 1.00 67.28  0  589 PHE A CE2 1 
ATOM   4659 C  CZ  . PHE A 1 590 ? 139.615 131.014 154.648 1.00 67.28  0  589 PHE A CZ  1 
ATOM   4660 N  N   . LYS A 1 591 ? 137.514 123.965 155.833 1.00 67.28  0  590 LYS A N   1 
ATOM   4661 C  CA  . LYS A 1 591 ? 137.793 122.536 155.919 1.00 67.28  0  590 LYS A CA  1 
ATOM   4662 C  C   . LYS A 1 591 ? 137.649 121.866 154.561 1.00 67.28  0  590 LYS A C   1 
ATOM   4663 O  O   . LYS A 1 591 ? 138.475 121.025 154.183 1.00 67.28  0  590 LYS A O   1 
ATOM   4664 C  CB  . LYS A 1 591 ? 136.862 121.886 156.942 1.00 67.28  0  590 LYS A CB  1 
ATOM   4665 C  CG  . LYS A 1 591 ? 137.101 120.403 157.155 1.00 67.28  0  590 LYS A CG  1 
ATOM   4666 C  CD  . LYS A 1 591 ? 136.246 119.870 158.293 1.00 67.28  0  590 LYS A CD  1 
ATOM   4667 C  CE  . LYS A 1 591 ? 136.677 118.472 158.699 1.00 67.28  0  590 LYS A CE  1 
ATOM   4668 N  NZ  . LYS A 1 591 ? 138.137 118.264 158.501 1.00 67.28  1  590 LYS A NZ  1 
ATOM   4669 N  N   . ARG A 1 592 ? 136.603 122.224 153.813 1.00 67.28  0  591 ARG A N   1 
ATOM   4670 C  CA  . ARG A 1 592 ? 136.464 121.695 152.459 1.00 67.28  0  591 ARG A CA  1 
ATOM   4671 C  C   . ARG A 1 592 ? 137.629 122.135 151.579 1.00 67.28  0  591 ARG A C   1 
ATOM   4672 O  O   . ARG A 1 592 ? 138.186 121.331 150.814 1.00 67.28  0  591 ARG A O   1 
ATOM   4673 C  CB  . ARG A 1 592 ? 135.133 122.138 151.853 1.00 67.28  0  591 ARG A CB  1 
ATOM   4674 C  CG  . ARG A 1 592 ? 133.912 121.614 152.589 1.00 67.28  0  591 ARG A CG  1 
ATOM   4675 C  CD  . ARG A 1 592 ? 132.704 121.537 151.670 1.00 67.28  0  591 ARG A CD  1 
ATOM   4676 N  NE  . ARG A 1 592 ? 132.353 122.837 151.113 1.00 67.28  0  591 ARG A NE  1 
ATOM   4677 C  CZ  . ARG A 1 592 ? 131.621 123.747 151.740 1.00 67.28  0  591 ARG A CZ  1 
ATOM   4678 N  NH1 . ARG A 1 592 ? 131.141 123.531 152.954 1.00 67.28  1  591 ARG A NH1 1 
ATOM   4679 N  NH2 . ARG A 1 592 ? 131.363 124.903 151.134 1.00 67.28  0  591 ARG A NH2 1 
ATOM   4680 N  N   . LYS A 1 593 ? 138.025 123.406 151.685 1.00 67.28  0  592 LYS A N   1 
ATOM   4681 C  CA  . LYS A 1 593 ? 139.156 123.884 150.897 1.00 67.28  0  592 LYS A CA  1 
ATOM   4682 C  C   . LYS A 1 593 ? 140.454 123.203 151.313 1.00 67.28  0  592 LYS A C   1 
ATOM   4683 O  O   . LYS A 1 593 ? 141.321 122.951 150.472 1.00 67.28  0  592 LYS A O   1 
ATOM   4684 C  CB  . LYS A 1 593 ? 139.276 125.402 151.007 1.00 67.28  0  592 LYS A CB  1 
ATOM   4685 C  CG  . LYS A 1 593 ? 138.150 126.136 150.313 1.00 67.28  0  592 LYS A CG  1 
ATOM   4686 C  CD  . LYS A 1 593 ? 138.336 127.636 150.366 1.00 67.28  0  592 LYS A CD  1 
ATOM   4687 C  CE  . LYS A 1 593 ? 137.163 128.340 149.714 1.00 67.28  0  592 LYS A CE  1 
ATOM   4688 N  NZ  . LYS A 1 593 ? 137.121 128.091 148.248 1.00 67.28  1  592 LYS A NZ  1 
ATOM   4689 N  N   . PHE A 1 594 ? 140.606 122.885 152.600 1.00 67.28  0  593 PHE A N   1 
ATOM   4690 C  CA  . PHE A 1 594 ? 141.803 122.179 153.042 1.00 67.28  0  593 PHE A CA  1 
ATOM   4691 C  C   . PHE A 1 594 ? 141.823 120.747 152.529 1.00 67.28  0  593 PHE A C   1 
ATOM   4692 O  O   . PHE A 1 594 ? 142.887 120.222 152.182 1.00 67.28  0  593 PHE A O   1 
ATOM   4693 C  CB  . PHE A 1 594 ? 141.906 122.195 154.565 1.00 67.28  0  593 PHE A CB  1 
ATOM   4694 C  CG  . PHE A 1 594 ? 143.059 121.397 155.093 1.00 67.28  0  593 PHE A CG  1 
ATOM   4695 C  CD1 . PHE A 1 594 ? 144.341 121.916 155.069 1.00 67.28  0  593 PHE A CD1 1 
ATOM   4696 C  CD2 . PHE A 1 594 ? 142.868 120.123 155.597 1.00 67.28  0  593 PHE A CD2 1 
ATOM   4697 C  CE1 . PHE A 1 594 ? 145.407 121.186 155.544 1.00 67.28  0  593 PHE A CE1 1 
ATOM   4698 C  CE2 . PHE A 1 594 ? 143.932 119.389 156.073 1.00 67.28  0  593 PHE A CE2 1 
ATOM   4699 C  CZ  . PHE A 1 594 ? 145.202 119.921 156.045 1.00 67.28  0  593 PHE A CZ  1 
ATOM   4700 N  N   . HIS A 1 595 ? 140.664 120.087 152.499 1.00 67.28  0  594 HIS A N   1 
ATOM   4701 C  CA  . HIS A 1 595 ? 140.607 118.749 151.920 1.00 67.28  0  594 HIS A CA  1 
ATOM   4702 C  C   . HIS A 1 595 ? 140.983 118.781 150.445 1.00 67.28  0  594 HIS A C   1 
ATOM   4703 O  O   . HIS A 1 595 ? 141.737 117.923 149.967 1.00 67.28  0  594 HIS A O   1 
ATOM   4704 C  CB  . HIS A 1 595 ? 139.218 118.144 152.113 1.00 67.28  0  594 HIS A CB  1 
ATOM   4705 C  CG  . HIS A 1 595 ? 138.999 117.557 153.472 1.00 67.28  0  594 HIS A CG  1 
ATOM   4706 N  ND1 . HIS A 1 595 ? 139.797 116.560 153.989 1.00 67.28  0  594 HIS A ND1 1 
ATOM   4707 C  CD2 . HIS A 1 595 ? 138.070 117.825 154.420 1.00 67.28  0  594 HIS A CD2 1 
ATOM   4708 C  CE1 . HIS A 1 595 ? 139.371 116.240 155.198 1.00 67.28  0  594 HIS A CE1 1 
ATOM   4709 N  NE2 . HIS A 1 595 ? 138.324 116.992 155.483 1.00 67.28  0  594 HIS A NE2 1 
ATOM   4710 N  N   . TYR A 1 596 ? 140.481 119.777 149.710 1.00 67.28  0  595 TYR A N   1 
ATOM   4711 C  CA  . TYR A 1 596 ? 140.882 119.923 148.313 1.00 67.28  0  595 TYR A CA  1 
ATOM   4712 C  C   . TYR A 1 596 ? 142.375 120.217 148.196 1.00 67.28  0  595 TYR A C   1 
ATOM   4713 O  O   . TYR A 1 596 ? 143.042 119.730 147.276 1.00 67.28  0  595 TYR A O   1 
ATOM   4714 C  CB  . TYR A 1 596 ? 140.067 121.021 147.635 1.00 67.28  0  595 TYR A CB  1 
ATOM   4715 C  CG  . TYR A 1 596 ? 140.324 121.119 146.150 1.00 67.28  0  595 TYR A CG  1 
ATOM   4716 C  CD1 . TYR A 1 596 ? 139.855 120.143 145.282 1.00 67.28  0  595 TYR A CD1 1 
ATOM   4717 C  CD2 . TYR A 1 596 ? 141.047 122.175 145.618 1.00 67.28  0  595 TYR A CD2 1 
ATOM   4718 C  CE1 . TYR A 1 596 ? 140.089 120.223 143.924 1.00 67.28  0  595 TYR A CE1 1 
ATOM   4719 C  CE2 . TYR A 1 596 ? 141.287 122.262 144.261 1.00 67.28  0  595 TYR A CE2 1 
ATOM   4720 C  CZ  . TYR A 1 596 ? 140.806 121.284 143.419 1.00 67.28  0  595 TYR A CZ  1 
ATOM   4721 O  OH  . TYR A 1 596 ? 141.042 121.366 142.066 1.00 67.28  0  595 TYR A OH  1 
ATOM   4722 N  N   . PHE A 1 597 ? 142.911 121.024 149.115 1.00 67.28  0  596 PHE A N   1 
ATOM   4723 C  CA  . PHE A 1 597 ? 144.337 121.337 149.121 1.00 67.28  0  596 PHE A CA  1 
ATOM   4724 C  C   . PHE A 1 597 ? 145.177 120.081 149.312 1.00 67.28  0  596 PHE A C   1 
ATOM   4725 O  O   . PHE A 1 597 ? 146.188 119.888 148.626 1.00 67.28  0  596 PHE A O   1 
ATOM   4726 C  CB  . PHE A 1 597 ? 144.622 122.353 150.229 1.00 67.28  0  596 PHE A CB  1 
ATOM   4727 C  CG  . PHE A 1 597 ? 146.025 122.887 150.233 1.00 67.28  0  596 PHE A CG  1 
ATOM   4728 C  CD1 . PHE A 1 597 ? 146.373 123.961 149.433 1.00 67.28  0  596 PHE A CD1 1 
ATOM   4729 C  CD2 . PHE A 1 597 ? 146.987 122.333 151.057 1.00 67.28  0  596 PHE A CD2 1 
ATOM   4730 C  CE1 . PHE A 1 597 ? 147.658 124.462 149.446 1.00 67.28  0  596 PHE A CE1 1 
ATOM   4731 C  CE2 . PHE A 1 597 ? 148.274 122.828 151.072 1.00 67.28  0  596 PHE A CE2 1 
ATOM   4732 C  CZ  . PHE A 1 597 ? 148.611 123.893 150.265 1.00 67.28  0  596 PHE A CZ  1 
ATOM   4733 N  N   . VAL A 1 598 ? 144.776 119.220 150.247 1.00 67.28  0  597 VAL A N   1 
ATOM   4734 C  CA  . VAL A 1 598 ? 145.493 117.968 150.472 1.00 67.28  0  597 VAL A CA  1 
ATOM   4735 C  C   . VAL A 1 598 ? 145.388 117.065 149.250 1.00 67.28  0  597 VAL A C   1 
ATOM   4736 O  O   . VAL A 1 598 ? 146.378 116.462 148.821 1.00 67.28  0  597 VAL A O   1 
ATOM   4737 C  CB  . VAL A 1 598 ? 144.969 117.267 151.738 1.00 67.28  0  597 VAL A CB  1 
ATOM   4738 C  CG1 . VAL A 1 598 ? 145.673 115.935 151.937 1.00 67.28  0  597 VAL A CG1 1 
ATOM   4739 C  CG2 . VAL A 1 598 ? 145.162 118.153 152.953 1.00 67.28  0  597 VAL A CG2 1 
ATOM   4740 N  N   . ASP A 1 599 ? 144.192 116.960 148.666 1.00 67.28  0  598 ASP A N   1 
ATOM   4741 C  CA  . ASP A 1 599 ? 144.010 116.092 147.509 1.00 67.28  0  598 ASP A CA  1 
ATOM   4742 C  C   . ASP A 1 599 ? 144.632 116.654 146.237 1.00 67.28  0  598 ASP A C   1 
ATOM   4743 O  O   . ASP A 1 599 ? 144.745 115.919 145.251 1.00 67.28  0  598 ASP A O   1 
ATOM   4744 C  CB  . ASP A 1 599 ? 142.521 115.828 147.282 1.00 67.28  0  598 ASP A CB  1 
ATOM   4745 C  CG  . ASP A 1 599 ? 141.911 114.967 148.371 1.00 67.28  0  598 ASP A CG  1 
ATOM   4746 O  OD1 . ASP A 1 599 ? 142.642 114.143 148.958 1.00 67.28  0  598 ASP A OD1 1 
ATOM   4747 O  OD2 . ASP A 1 599 ? 140.700 115.115 148.640 1.00 67.28  -1 598 ASP A OD2 1 
ATOM   4748 N  N   . SER A 1 600 ? 145.036 117.922 146.230 1.00 67.28  0  599 SER A N   1 
ATOM   4749 C  CA  . SER A 1 600 ? 145.613 118.559 145.052 1.00 67.28  0  599 SER A CA  1 
ATOM   4750 C  C   . SER A 1 600 ? 146.870 119.337 145.414 1.00 67.28  0  599 SER A C   1 
ATOM   4751 O  O   . SER A 1 600 ? 147.127 120.421 144.883 1.00 67.28  0  599 SER A O   1 
ATOM   4752 C  CB  . SER A 1 600 ? 144.596 119.471 144.371 1.00 67.28  0  599 SER A CB  1 
ATOM   4753 O  OG  . SER A 1 600 ? 145.214 120.273 143.380 1.00 67.28  0  599 SER A OG  1 
ATOM   4754 N  N   . ILE A 1 601 ? 147.679 118.794 146.329 1.00 67.28  0  600 ILE A N   1 
ATOM   4755 C  CA  . ILE A 1 601 ? 148.941 119.437 146.688 1.00 67.28  0  600 ILE A CA  1 
ATOM   4756 C  C   . ILE A 1 601 ? 150.026 119.207 145.651 1.00 67.28  0  600 ILE A C   1 
ATOM   4757 O  O   . ILE A 1 601 ? 151.088 119.838 145.729 1.00 67.28  0  600 ILE A O   1 
ATOM   4758 C  CB  . ILE A 1 601 ? 149.445 118.951 148.061 1.00 67.28  0  600 ILE A CB  1 
ATOM   4759 C  CG1 . ILE A 1 601 ? 150.343 120.008 148.709 1.00 67.28  0  600 ILE A CG1 1 
ATOM   4760 C  CG2 . ILE A 1 601 ? 150.180 117.626 147.926 1.00 67.28  0  600 ILE A CG2 1 
ATOM   4761 C  CD1 . ILE A 1 601 ? 150.868 119.618 150.069 1.00 67.28  0  600 ILE A CD1 1 
ATOM   4762 N  N   . ALA A 1 602 ? 149.788 118.325 144.676 1.00 67.28  0  601 ALA A N   1 
ATOM   4763 C  CA  . ALA A 1 602 ? 150.806 118.035 143.673 1.00 67.28  0  601 ALA A CA  1 
ATOM   4764 C  C   . ALA A 1 602 ? 151.199 119.279 142.890 1.00 67.28  0  601 ALA A C   1 
ATOM   4765 O  O   . ALA A 1 602 ? 152.364 119.422 142.505 1.00 67.28  0  601 ALA A O   1 
ATOM   4766 C  CB  . ALA A 1 602 ? 150.311 116.945 142.722 1.00 67.28  0  601 ALA A CB  1 
ATOM   4767 N  N   . GLY A 1 603 ? 150.254 120.191 142.656 1.00 67.28  0  602 GLY A N   1 
ATOM   4768 C  CA  . GLY A 1 603 ? 150.577 121.404 141.922 1.00 67.28  0  602 GLY A CA  1 
ATOM   4769 C  C   . GLY A 1 603 ? 151.620 122.254 142.624 1.00 67.28  0  602 GLY A C   1 
ATOM   4770 O  O   . GLY A 1 603 ? 152.498 122.833 141.981 1.00 67.28  0  602 GLY A O   1 
ATOM   4771 N  N   . MET A 1 604 ? 151.537 122.340 143.952 1.00 67.28  0  603 MET A N   1 
ATOM   4772 C  CA  . MET A 1 604 ? 152.517 123.108 144.710 1.00 67.28  0  603 MET A CA  1 
ATOM   4773 C  C   . MET A 1 604 ? 153.844 122.367 144.824 1.00 67.28  0  603 MET A C   1 
ATOM   4774 O  O   . MET A 1 604 ? 154.904 122.998 144.899 1.00 67.28  0  603 MET A O   1 
ATOM   4775 C  CB  . MET A 1 604 ? 151.967 123.433 146.097 1.00 67.28  0  603 MET A CB  1 
ATOM   4776 C  CG  . MET A 1 604 ? 152.586 124.657 146.740 1.00 67.28  0  603 MET A CG  1 
ATOM   4777 S  SD  . MET A 1 604 ? 151.520 125.348 148.015 1.00 67.28  0  603 MET A SD  1 
ATOM   4778 C  CE  . MET A 1 604 ? 152.667 126.421 148.866 1.00 67.28  0  603 MET A CE  1 
ATOM   4779 N  N   . ASP A 1 605 ? 153.813 121.036 144.868 1.00 67.28  0  604 ASP A N   1 
ATOM   4780 C  CA  . ASP A 1 605 ? 155.089 120.300 145.053 1.00 67.28  0  604 ASP A CA  1 
ATOM   4781 C  C   . ASP A 1 605 ? 155.969 120.555 143.829 1.00 67.28  0  604 ASP A C   1 
ATOM   4782 O  O   . ASP A 1 605 ? 157.199 120.669 143.998 1.00 67.28  0  604 ASP A O   1 
ATOM   4783 C  CB  . ASP A 1 605 ? 154.868 118.803 145.276 1.00 67.28  0  604 ASP A CB  1 
ATOM   4784 C  CG  . ASP A 1 605 ? 156.124 118.073 145.716 1.00 67.28  0  604 ASP A CG  1 
ATOM   4785 O  OD1 . ASP A 1 605 ? 156.862 118.630 146.551 1.00 67.28  0  604 ASP A OD1 1 
ATOM   4786 O  OD2 . ASP A 1 605 ? 156.354 116.955 145.218 1.00 67.28  -1 604 ASP A OD2 1 
ATOM   4787 N  N   . GLU A 1 606 ? 155.355 120.676 142.651 1.00 67.28  0  605 GLU A N   1 
ATOM   4788 C  CA  . GLU A 1 606 ? 156.136 120.842 141.397 1.00 67.28  0  605 GLU A CA  1 
ATOM   4789 C  C   . GLU A 1 606 ? 156.921 122.160 141.426 1.00 67.28  0  605 GLU A C   1 
ATOM   4790 O  O   . GLU A 1 606 ? 158.128 122.123 141.116 1.00 67.28  0  605 GLU A O   1 
ATOM   4791 C  CB  . GLU A 1 606 ? 155.207 120.770 140.184 1.00 67.28  0  605 GLU A CB  1 
ATOM   4792 C  CG  . GLU A 1 606 ? 154.579 119.403 139.961 1.00 67.28  0  605 GLU A CG  1 
ATOM   4793 C  CD  . GLU A 1 606 ? 153.589 119.273 138.814 1.00 67.28  0  605 GLU A CD  1 
ATOM   4794 O  OE1 . GLU A 1 606 ? 153.198 120.308 138.243 1.00 67.28  0  605 GLU A OE1 1 
ATOM   4795 O  OE2 . GLU A 1 606 ? 153.198 118.132 138.500 1.00 67.28  -1 605 GLU A OE2 1 
ATOM   4796 N  N   . LEU A 1 607 ? 156.273 123.272 141.784 1.00 67.28  0  606 LEU A N   1 
ATOM   4797 C  CA  . LEU A 1 607 ? 156.965 124.590 141.746 1.00 67.28  0  606 LEU A CA  1 
ATOM   4798 C  C   . LEU A 1 607 ? 158.074 124.602 142.799 1.00 67.28  0  606 LEU A C   1 
ATOM   4799 O  O   . LEU A 1 607 ? 159.022 125.393 142.642 1.00 67.28  0  606 LEU A O   1 
ATOM   4800 C  CB  . LEU A 1 607 ? 155.958 125.717 141.993 1.00 67.28  0  606 LEU A CB  1 
ATOM   4801 C  CG  . LEU A 1 607 ? 156.494 127.131 141.783 1.00 67.28  0  606 LEU A CG  1 
ATOM   4802 C  CD1 . LEU A 1 607 ? 157.110 127.277 140.400 1.00 67.28  0  606 LEU A CD1 1 
ATOM   4803 C  CD2 . LEU A 1 607 ? 155.395 128.162 141.990 1.00 67.28  0  606 LEU A CD2 1 
ATOM   4804 N  N   . MET A 1 608 ? 157.961 123.756 143.825 1.00 67.28  0  607 MET A N   1 
ATOM   4805 C  CA  . MET A 1 608 ? 158.968 123.753 144.918 1.00 67.28  0  607 MET A CA  1 
ATOM   4806 C  C   . MET A 1 608 ? 160.164 122.890 144.504 1.00 67.28  0  607 MET A C   1 
ATOM   4807 O  O   . MET A 1 608 ? 161.296 123.235 144.896 1.00 67.28  0  607 MET A O   1 
ATOM   4808 C  CB  . MET A 1 608 ? 158.369 123.218 146.220 1.00 67.28  0  607 MET A CB  1 
ATOM   4809 C  CG  . MET A 1 608 ? 157.204 124.041 146.727 1.00 67.28  0  607 MET A CG  1 
ATOM   4810 S  SD  . MET A 1 608 ? 157.720 125.312 147.904 1.00 67.28  0  607 MET A SD  1 
ATOM   4811 C  CE  . MET A 1 608 ? 156.173 126.182 148.145 1.00 67.28  0  607 MET A CE  1 
ATOM   4812 N  N   . GLU A 1 609 ? 159.928 121.824 143.736 1.00 67.28  0  608 GLU A N   1 
ATOM   4813 C  CA  . GLU A 1 609 ? 161.035 120.998 143.265 1.00 67.28  0  608 GLU A CA  1 
ATOM   4814 C  C   . GLU A 1 609 ? 161.922 121.759 142.287 1.00 67.28  0  608 GLU A C   1 
ATOM   4815 O  O   . GLU A 1 609 ? 163.152 121.651 142.338 1.00 67.28  0  608 GLU A O   1 
ATOM   4816 C  CB  . GLU A 1 609 ? 160.490 119.721 142.625 1.00 67.28  0  608 GLU A CB  1 
ATOM   4817 C  CG  . GLU A 1 609 ? 161.532 118.854 141.947 1.00 67.28  0  608 GLU A CG  1 
ATOM   4818 C  CD  . GLU A 1 609 ? 161.124 117.394 141.898 1.00 67.28  0  608 GLU A CD  1 
ATOM   4819 O  OE1 . GLU A 1 609 ? 159.921 117.106 142.067 1.00 67.28  0  608 GLU A OE1 1 
ATOM   4820 O  OE2 . GLU A 1 609 ? 162.007 116.535 141.695 1.00 67.28  -1 608 GLU A OE2 1 
ATOM   4821 N  N   . VAL A 1 610 ? 161.317 122.536 141.388 1.00 67.28  0  609 VAL A N   1 
ATOM   4822 C  CA  . VAL A 1 610 ? 162.102 123.265 140.397 1.00 67.28  0  609 VAL A CA  1 
ATOM   4823 C  C   . VAL A 1 610 ? 162.735 124.526 140.968 1.00 67.28  0  609 VAL A C   1 
ATOM   4824 O  O   . VAL A 1 610 ? 163.618 125.109 140.326 1.00 67.28  0  609 VAL A O   1 
ATOM   4825 C  CB  . VAL A 1 610 ? 161.239 123.627 139.178 1.00 67.28  0  609 VAL A CB  1 
ATOM   4826 C  CG1 . VAL A 1 610 ? 160.734 122.367 138.497 1.00 67.28  0  609 VAL A CG1 1 
ATOM   4827 C  CG2 . VAL A 1 610 ? 160.075 124.512 139.596 1.00 67.28  0  609 VAL A CG2 1 
ATOM   4828 N  N   . SER A 1 611 ? 162.314 124.968 142.151 1.00 67.28  0  610 SER A N   1 
ATOM   4829 C  CA  . SER A 1 611 ? 162.800 126.213 142.733 1.00 67.28  0  610 SER A CA  1 
ATOM   4830 C  C   . SER A 1 611 ? 163.799 125.994 143.862 1.00 67.28  0  610 SER A C   1 
ATOM   4831 O  O   . SER A 1 611 ? 164.823 126.680 143.922 1.00 67.28  0  610 SER A O   1 
ATOM   4832 C  CB  . SER A 1 611 ? 161.618 127.047 143.241 1.00 67.28  0  610 SER A CB  1 
ATOM   4833 O  OG  . SER A 1 611 ? 162.007 128.386 143.491 1.00 67.28  0  610 SER A OG  1 
ATOM   4834 N  N   . PHE A 1 612 ? 163.527 125.050 144.762 1.00 67.28  0  611 PHE A N   1 
ATOM   4835 C  CA  . PHE A 1 612 ? 164.343 124.856 145.954 1.00 67.28  0  611 PHE A CA  1 
ATOM   4836 C  C   . PHE A 1 612 ? 165.182 123.584 145.906 1.00 67.28  0  611 PHE A C   1 
ATOM   4837 O  O   . PHE A 1 612 ? 165.737 123.184 146.935 1.00 67.28  0  611 PHE A O   1 
ATOM   4838 C  CB  . PHE A 1 612 ? 163.459 124.853 147.203 1.00 67.28  0  611 PHE A CB  1 
ATOM   4839 C  CG  . PHE A 1 612 ? 162.908 126.205 147.558 1.00 67.28  0  611 PHE A CG  1 
ATOM   4840 C  CD1 . PHE A 1 612 ? 161.855 126.750 146.844 1.00 67.28  0  611 PHE A CD1 1 
ATOM   4841 C  CD2 . PHE A 1 612 ? 163.449 126.933 148.603 1.00 67.28  0  611 PHE A CD2 1 
ATOM   4842 C  CE1 . PHE A 1 612 ? 161.351 127.992 147.168 1.00 67.28  0  611 PHE A CE1 1 
ATOM   4843 C  CE2 . PHE A 1 612 ? 162.949 128.176 148.931 1.00 67.28  0  611 PHE A CE2 1 
ATOM   4844 C  CZ  . PHE A 1 612 ? 161.899 128.706 148.212 1.00 67.28  0  611 PHE A CZ  1 
ATOM   4845 N  N   . SER A 1 613 ? 165.289 122.938 144.748 1.00 65.58  0  612 SER A N   1 
ATOM   4846 C  CA  . SER A 1 613 ? 166.136 121.762 144.593 1.00 65.58  0  612 SER A CA  1 
ATOM   4847 C  C   . SER A 1 613 ? 167.132 122.007 143.469 1.00 65.58  0  612 SER A C   1 
ATOM   4848 O  O   . SER A 1 613 ? 166.719 122.170 142.308 1.00 65.58  0  612 SER A O   1 
ATOM   4849 C  CB  . SER A 1 613 ? 165.303 120.511 144.307 1.00 65.58  0  612 SER A CB  1 
ATOM   4850 O  OG  . SER A 1 613 ? 166.133 119.383 144.099 1.00 65.58  0  612 SER A OG  1 
ATOM   4851 N  N   . PRO A 1 614 ? 168.439 122.042 143.749 1.00 70.55  0  613 PRO A N   1 
ATOM   4852 C  CA  . PRO A 1 614 ? 169.409 122.321 142.682 1.00 70.55  0  613 PRO A CA  1 
ATOM   4853 C  C   . PRO A 1 614 ? 169.713 121.129 141.792 1.00 70.55  0  613 PRO A C   1 
ATOM   4854 O  O   . PRO A 1 614 ? 170.217 121.329 140.679 1.00 70.55  0  613 PRO A O   1 
ATOM   4855 C  CB  . PRO A 1 614 ? 170.657 122.760 143.457 1.00 70.55  0  613 PRO A CB  1 
ATOM   4856 C  CG  . PRO A 1 614 ? 170.566 121.998 144.741 1.00 70.55  0  613 PRO A CG  1 
ATOM   4857 C  CD  . PRO A 1 614 ? 169.093 121.837 145.054 1.00 70.55  0  613 PRO A CD  1 
ATOM   4858 N  N   . LEU A 1 615 ? 169.429 119.907 142.236 1.00 72.37  0  614 LEU A N   1 
ATOM   4859 C  CA  . LEU A 1 615 ? 169.725 118.707 141.467 1.00 72.37  0  614 LEU A CA  1 
ATOM   4860 C  C   . LEU A 1 615 ? 168.552 118.249 140.610 1.00 72.37  0  614 LEU A C   1 
ATOM   4861 O  O   . LEU A 1 615 ? 168.645 117.205 139.956 1.00 72.37  0  614 LEU A O   1 
ATOM   4862 C  CB  . LEU A 1 615 ? 170.176 117.581 142.406 1.00 72.37  0  614 LEU A CB  1 
ATOM   4863 C  CG  . LEU A 1 615 ? 169.240 117.087 143.516 1.00 72.37  0  614 LEU A CG  1 
ATOM   4864 C  CD1 . LEU A 1 615 ? 168.267 116.017 143.028 1.00 72.37  0  614 LEU A CD1 1 
ATOM   4865 C  CD2 . LEU A 1 615 ? 170.047 116.576 144.701 1.00 72.37  0  614 LEU A CD2 1 
ATOM   4866 N  N   . ALA A 1 616 ? 167.450 119.006 140.594 1.00 69.22  0  615 ALA A N   1 
ATOM   4867 C  CA  . ALA A 1 616 ? 166.288 118.622 139.802 1.00 69.22  0  615 ALA A CA  1 
ATOM   4868 C  C   . ALA A 1 616 ? 165.712 119.793 139.012 1.00 69.22  0  615 ALA A C   1 
ATOM   4869 O  O   . ALA A 1 616 ? 164.566 119.714 138.553 1.00 69.22  0  615 ALA A O   1 
ATOM   4870 C  CB  . ALA A 1 616 ? 165.197 118.017 140.693 1.00 69.22  0  615 ALA A CB  1 
ATOM   4871 N  N   . ALA A 1 617 ? 166.472 120.874 138.840 1.00 68.04  0  616 ALA A N   1 
ATOM   4872 C  CA  . ALA A 1 617 ? 166.008 122.045 138.107 1.00 68.04  0  616 ALA A CA  1 
ATOM   4873 C  C   . ALA A 1 617 ? 166.794 122.286 136.825 1.00 68.04  0  616 ALA A C   1 
ATOM   4874 O  O   . ALA A 1 617 ? 166.692 123.372 136.243 1.00 68.04  0  616 ALA A O   1 
ATOM   4875 C  CB  . ALA A 1 617 ? 166.070 123.290 138.997 1.00 68.04  0  616 ALA A CB  1 
ATOM   4876 N  N   . THR A 1 618 ? 167.573 121.309 136.368 1.00 68.18  0  617 THR A N   1 
ATOM   4877 C  CA  . THR A 1 618 ? 168.379 121.446 135.162 1.00 68.18  0  617 THR A CA  1 
ATOM   4878 C  C   . THR A 1 618 ? 167.703 120.699 134.020 1.00 68.18  0  617 THR A C   1 
ATOM   4879 O  O   . THR A 1 618 ? 167.497 119.483 134.104 1.00 68.18  0  617 THR A O   1 
ATOM   4880 C  CB  . THR A 1 618 ? 169.794 120.912 135.386 1.00 68.18  0  617 THR A CB  1 
ATOM   4881 O  OG1 . THR A 1 618 ? 169.731 119.678 136.111 1.00 68.18  0  617 THR A OG1 1 
ATOM   4882 C  CG2 . THR A 1 618 ? 170.622 121.916 136.174 1.00 68.18  0  617 THR A CG2 1 
ATOM   4883 N  N   . GLY A 1 619 ? 167.363 121.426 132.956 1.00 67.22  0  618 GLY A N   1 
ATOM   4884 C  CA  . GLY A 1 619 ? 166.720 120.830 131.803 1.00 67.22  0  618 GLY A CA  1 
ATOM   4885 C  C   . GLY A 1 619 ? 167.045 121.601 130.543 1.00 67.22  0  618 GLY A C   1 
ATOM   4886 O  O   . GLY A 1 619 ? 167.554 122.723 130.585 1.00 67.22  0  618 GLY A O   1 
ATOM   4887 N  N   . LYS A 1 620 ? 166.741 120.976 129.410 1.00 66.83  0  619 LYS A N   1 
ATOM   4888 C  CA  . LYS A 1 620 ? 167.015 121.600 128.125 1.00 66.83  0  619 LYS A CA  1 
ATOM   4889 C  C   . LYS A 1 620 ? 166.032 122.741 127.869 1.00 66.83  0  619 LYS A C   1 
ATOM   4890 O  O   . LYS A 1 620 ? 164.843 122.620 128.179 1.00 66.83  0  619 LYS A O   1 
ATOM   4891 C  CB  . LYS A 1 620 ? 166.928 120.572 126.995 1.00 66.83  0  619 LYS A CB  1 
ATOM   4892 C  CG  . LYS A 1 620 ? 167.832 119.356 127.163 1.00 66.83  0  619 LYS A CG  1 
ATOM   4893 C  CD  . LYS A 1 620 ? 169.180 119.724 127.767 1.00 66.83  0  619 LYS A CD  1 
ATOM   4894 C  CE  . LYS A 1 620 ? 170.078 118.505 127.902 1.00 66.83  0  619 LYS A CE  1 
ATOM   4895 N  NZ  . LYS A 1 620 ? 169.308 117.288 128.283 1.00 66.83  1  619 LYS A NZ  1 
ATOM   4896 N  N   . PRO A 1 621 ? 166.499 123.860 127.317 1.00 66.88  0  620 PRO A N   1 
ATOM   4897 C  CA  . PRO A 1 621 ? 165.585 124.961 126.992 1.00 66.88  0  620 PRO A CA  1 
ATOM   4898 C  C   . PRO A 1 621 ? 164.576 124.553 125.929 1.00 66.88  0  620 PRO A C   1 
ATOM   4899 O  O   . PRO A 1 621 ? 164.838 123.690 125.089 1.00 66.88  0  620 PRO A O   1 
ATOM   4900 C  CB  . PRO A 1 621 ? 166.523 126.060 126.482 1.00 66.88  0  620 PRO A CB  1 
ATOM   4901 C  CG  . PRO A 1 621 ? 167.851 125.732 127.082 1.00 66.88  0  620 PRO A CG  1 
ATOM   4902 C  CD  . PRO A 1 621 ? 167.907 124.234 127.111 1.00 66.88  0  620 PRO A CD  1 
ATOM   4903 N  N   . LEU A 1 622 ? 163.412 125.189 125.974 1.00 69.92  0  621 LEU A N   1 
ATOM   4904 C  CA  . LEU A 1 622 ? 162.304 124.831 125.095 1.00 69.92  0  621 LEU A CA  1 
ATOM   4905 C  C   . LEU A 1 622 ? 161.494 126.093 124.804 1.00 69.92  0  621 LEU A C   1 
ATOM   4906 O  O   . LEU A 1 622 ? 161.994 127.212 124.958 1.00 69.92  0  621 LEU A O   1 
ATOM   4907 C  CB  . LEU A 1 622 ? 161.468 123.699 125.715 1.00 69.92  0  621 LEU A CB  1 
ATOM   4908 C  CG  . LEU A 1 622 ? 160.866 122.707 124.718 1.00 69.92  0  621 LEU A CG  1 
ATOM   4909 C  CD1 . LEU A 1 622 ? 161.962 121.978 123.959 1.00 69.92  0  621 LEU A CD1 1 
ATOM   4910 C  CD2 . LEU A 1 622 ? 159.955 121.718 125.426 1.00 69.92  0  621 LEU A CD2 1 
ATOM   4911 N  N   . SER A 1 623 ? 160.251 125.901 124.358 1.00 72.51  0  622 SER A N   1 
ATOM   4912 C  CA  . SER A 1 623 ? 159.399 126.978 123.864 1.00 72.51  0  622 SER A CA  1 
ATOM   4913 C  C   . SER A 1 623 ? 159.365 128.171 124.814 1.00 72.51  0  622 SER A C   1 
ATOM   4914 O  O   . SER A 1 623 ? 159.522 128.034 126.031 1.00 72.51  0  622 SER A O   1 
ATOM   4915 C  CB  . SER A 1 623 ? 157.979 126.454 123.643 1.00 72.51  0  622 SER A CB  1 
ATOM   4916 O  OG  . SER A 1 623 ? 157.392 126.045 124.866 1.00 72.51  0  622 SER A OG  1 
ATOM   4917 N  N   . ARG A 1 624 ? 159.148 129.351 124.235 1.00 73.74  0  623 ARG A N   1 
ATOM   4918 C  CA  . ARG A 1 624 ? 159.145 130.599 124.984 1.00 73.74  0  623 ARG A CA  1 
ATOM   4919 C  C   . ARG A 1 624 ? 158.025 130.619 126.020 1.00 73.74  0  623 ARG A C   1 
ATOM   4920 O  O   . ARG A 1 624 ? 157.055 129.861 125.948 1.00 73.74  0  623 ARG A O   1 
ATOM   4921 C  CB  . ARG A 1 624 ? 158.957 131.793 124.047 1.00 73.74  0  623 ARG A CB  1 
ATOM   4922 C  CG  . ARG A 1 624 ? 159.850 131.822 122.821 1.00 73.74  0  623 ARG A CG  1 
ATOM   4923 C  CD  . ARG A 1 624 ? 161.270 132.229 123.157 1.00 73.74  0  623 ARG A CD  1 
ATOM   4924 N  NE  . ARG A 1 624 ? 161.954 132.791 121.998 1.00 73.74  0  623 ARG A NE  1 
ATOM   4925 C  CZ  . ARG A 1 624 ? 162.399 132.083 120.968 1.00 73.74  0  623 ARG A CZ  1 
ATOM   4926 N  NH1 . ARG A 1 624 ? 162.249 130.770 120.913 1.00 73.74  1  623 ARG A NH1 1 
ATOM   4927 N  NH2 . ARG A 1 624 ? 163.007 132.711 119.966 1.00 73.74  0  623 ARG A NH2 1 
ATOM   4928 N  N   . CYS A 1 625 ? 158.167 131.520 126.987 1.00 75.17  0  624 CYS A N   1 
ATOM   4929 C  CA  . CYS A 1 625 ? 157.087 131.833 127.912 1.00 75.17  0  624 CYS A CA  1 
ATOM   4930 C  C   . CYS A 1 625 ? 156.071 132.712 127.184 1.00 75.17  0  624 CYS A C   1 
ATOM   4931 O  O   . CYS A 1 625 ? 156.344 133.260 126.113 1.00 75.17  0  624 CYS A O   1 
ATOM   4932 C  CB  . CYS A 1 625 ? 157.647 132.501 129.167 1.00 75.17  0  624 CYS A CB  1 
ATOM   4933 S  SG  . CYS A 1 625 ? 156.465 132.755 130.518 1.00 75.17  0  624 CYS A SG  1 
ATOM   4934 N  N   . GLY A 1 626 ? 154.883 132.863 127.758 1.00 76.25  0  625 GLY A N   1 
ATOM   4935 C  CA  . GLY A 1 626 ? 153.862 133.682 127.137 1.00 76.25  0  625 GLY A CA  1 
ATOM   4936 C  C   . GLY A 1 626 ? 153.701 135.014 127.833 1.00 76.25  0  625 GLY A C   1 
ATOM   4937 O  O   . GLY A 1 626 ? 152.953 135.885 127.378 1.00 76.25  0  625 GLY A O   1 
ATOM   4938 N  N   . LYS A 1 627 ? 154.407 135.177 128.950 1.00 72.52  0  626 LYS A N   1 
ATOM   4939 C  CA  . LYS A 1 627 ? 154.386 136.417 129.715 1.00 72.52  0  626 LYS A CA  1 
ATOM   4940 C  C   . LYS A 1 627 ? 155.765 137.071 129.724 1.00 72.52  0  626 LYS A C   1 
ATOM   4941 O  O   . LYS A 1 627 ? 155.889 138.281 129.938 1.00 72.52  0  626 LYS A O   1 
ATOM   4942 C  CB  . LYS A 1 627 ? 153.908 136.137 131.145 1.00 72.52  0  626 LYS A CB  1 
ATOM   4943 C  CG  . LYS A 1 627 ? 152.611 135.349 131.219 1.00 72.52  0  626 LYS A CG  1 
ATOM   4944 C  CD  . LYS A 1 627 ? 151.933 135.516 132.567 1.00 72.52  0  626 LYS A CD  1 
ATOM   4945 C  CE  . LYS A 1 627 ? 150.958 134.383 132.832 1.00 72.52  0  626 LYS A CE  1 
ATOM   4946 N  NZ  . LYS A 1 627 ? 151.410 133.515 133.954 1.00 72.52  1  626 LYS A NZ  1 
ATOM   4947 N  N   . CYS A 1 628 ? 156.807 136.277 129.490 1.00 72.52  0  627 CYS A N   1 
ATOM   4948 C  CA  . CYS A 1 628 ? 158.188 136.725 129.602 1.00 72.52  0  627 CYS A CA  1 
ATOM   4949 C  C   . CYS A 1 628 ? 158.894 136.843 128.258 1.00 72.52  0  627 CYS A C   1 
ATOM   4950 O  O   . CYS A 1 628 ? 159.861 137.604 128.150 1.00 72.52  0  627 CYS A O   1 
ATOM   4951 C  CB  . CYS A 1 628 ? 158.973 135.766 130.500 1.00 72.52  0  627 CYS A CB  1 
ATOM   4952 S  SG  . CYS A 1 628 ? 158.379 135.660 132.197 1.00 72.52  0  627 CYS A SG  1 
ATOM   4953 N  N   . HIS A 1 629 ? 158.436 136.116 127.240 1.00 71.84  0  628 HIS A N   1 
ATOM   4954 C  CA  . HIS A 1 629 ? 159.187 135.929 125.998 1.00 71.84  0  628 HIS A CA  1 
ATOM   4955 C  C   . HIS A 1 629 ? 160.594 135.418 126.295 1.00 71.84  0  628 HIS A C   1 
ATOM   4956 O  O   . HIS A 1 629 ? 161.589 135.867 125.723 1.00 71.84  0  628 HIS A O   1 
ATOM   4957 C  CB  . HIS A 1 629 ? 159.233 137.213 125.170 1.00 71.84  0  628 HIS A CB  1 
ATOM   4958 C  CG  . HIS A 1 629 ? 157.898 137.653 124.659 1.00 71.84  0  628 HIS A CG  1 
ATOM   4959 N  ND1 . HIS A 1 629 ? 157.263 137.027 123.608 1.00 71.84  0  628 HIS A ND1 1 
ATOM   4960 C  CD2 . HIS A 1 629 ? 157.082 138.661 125.044 1.00 71.84  0  628 HIS A CD2 1 
ATOM   4961 C  CE1 . HIS A 1 629 ? 156.111 137.628 123.371 1.00 71.84  0  628 HIS A CE1 1 
ATOM   4962 N  NE2 . HIS A 1 629 ? 155.977 138.623 124.228 1.00 71.84  0  628 HIS A NE2 1 
ATOM   4963 N  N   . ARG A 1 630 ? 160.664 134.457 127.212 1.00 70.40  0  629 ARG A N   1 
ATOM   4964 C  CA  . ARG A 1 630 ? 161.918 133.872 127.654 1.00 70.40  0  629 ARG A CA  1 
ATOM   4965 C  C   . ARG A 1 630 ? 161.813 132.354 127.596 1.00 70.40  0  629 ARG A C   1 
ATOM   4966 O  O   . ARG A 1 630 ? 160.722 131.780 127.652 1.00 70.40  0  629 ARG A O   1 
ATOM   4967 C  CB  . ARG A 1 630 ? 162.279 134.333 129.073 1.00 70.40  0  629 ARG A CB  1 
ATOM   4968 C  CG  . ARG A 1 630 ? 163.769 134.504 129.309 1.00 70.40  0  629 ARG A CG  1 
ATOM   4969 C  CD  . ARG A 1 630 ? 164.038 135.282 130.586 1.00 70.40  0  629 ARG A CD  1 
ATOM   4970 N  NE  . ARG A 1 630 ? 163.239 136.498 130.663 1.00 70.40  0  629 ARG A NE  1 
ATOM   4971 C  CZ  . ARG A 1 630 ? 163.670 137.701 130.311 1.00 70.40  0  629 ARG A CZ  1 
ATOM   4972 N  NH1 . ARG A 1 630 ? 164.896 137.888 129.851 1.00 70.40  1  629 ARG A NH1 1 
ATOM   4973 N  NH2 . ARG A 1 630 ? 162.851 138.743 130.422 1.00 70.40  0  629 ARG A NH2 1 
ATOM   4974 N  N   . PHE A 1 631 ? 162.969 131.707 127.479 1.00 68.33  0  630 PHE A N   1 
ATOM   4975 C  CA  . PHE A 1 631 ? 163.014 130.258 127.358 1.00 68.33  0  630 PHE A CA  1 
ATOM   4976 C  C   . PHE A 1 631 ? 162.511 129.585 128.630 1.00 68.33  0  630 PHE A C   1 
ATOM   4977 O  O   . PHE A 1 631 ? 162.730 130.064 129.746 1.00 68.33  0  630 PHE A O   1 
ATOM   4978 C  CB  . PHE A 1 631 ? 164.438 129.794 127.058 1.00 68.33  0  630 PHE A CB  1 
ATOM   4979 C  CG  . PHE A 1 631 ? 164.790 129.815 125.598 1.00 68.33  0  630 PHE A CG  1 
ATOM   4980 C  CD1 . PHE A 1 631 ? 163.954 130.416 124.676 1.00 68.33  0  630 PHE A CD1 1 
ATOM   4981 C  CD2 . PHE A 1 631 ? 165.961 129.227 125.149 1.00 68.33  0  630 PHE A CD2 1 
ATOM   4982 C  CE1 . PHE A 1 631 ? 164.279 130.433 123.334 1.00 68.33  0  630 PHE A CE1 1 
ATOM   4983 C  CE2 . PHE A 1 631 ? 166.292 129.241 123.808 1.00 68.33  0  630 PHE A CE2 1 
ATOM   4984 C  CZ  . PHE A 1 631 ? 165.449 129.845 122.899 1.00 68.33  0  630 PHE A CZ  1 
ATOM   4985 N  N   . MET A 1 632 ? 161.829 128.458 128.449 1.00 66.52  0  631 MET A N   1 
ATOM   4986 C  CA  . MET A 1 632 ? 161.360 127.629 129.547 1.00 66.52  0  631 MET A CA  1 
ATOM   4987 C  C   . MET A 1 632 ? 162.095 126.296 129.527 1.00 66.52  0  631 MET A C   1 
ATOM   4988 O  O   . MET A 1 632 ? 162.253 125.679 128.470 1.00 66.52  0  631 MET A O   1 
ATOM   4989 C  CB  . MET A 1 632 ? 159.849 127.400 129.464 1.00 66.52  0  631 MET A CB  1 
ATOM   4990 C  CG  . MET A 1 632 ? 159.033 128.395 130.271 1.00 66.52  0  631 MET A CG  1 
ATOM   4991 S  SD  . MET A 1 632 ? 157.269 128.030 130.288 1.00 66.52  0  631 MET A SD  1 
ATOM   4992 C  CE  . MET A 1 632 ? 156.913 127.991 128.536 1.00 66.52  0  631 MET A CE  1 
ATOM   4993 N  N   . LYS A 1 633 ? 162.538 125.856 130.700 1.00 65.26  0  632 LYS A N   1 
ATOM   4994 C  CA  . LYS A 1 633 ? 163.322 124.638 130.834 1.00 65.26  0  632 LYS A CA  1 
ATOM   4995 C  C   . LYS A 1 633 ? 162.403 123.432 130.978 1.00 65.26  0  632 LYS A C   1 
ATOM   4996 O  O   . LYS A 1 633 ? 161.384 123.492 131.671 1.00 65.26  0  632 LYS A O   1 
ATOM   4997 C  CB  . LYS A 1 633 ? 164.266 124.732 132.034 1.00 65.26  0  632 LYS A CB  1 
ATOM   4998 C  CG  . LYS A 1 633 ? 165.064 126.026 132.075 1.00 65.26  0  632 LYS A CG  1 
ATOM   4999 C  CD  . LYS A 1 633 ? 166.314 125.885 132.926 1.00 65.26  0  632 LYS A CD  1 
ATOM   5000 C  CE  . LYS A 1 633 ? 165.993 126.033 134.402 1.00 65.26  0  632 LYS A CE  1 
ATOM   5001 N  NZ  . LYS A 1 633 ? 166.017 127.457 134.833 1.00 65.26  1  632 LYS A NZ  1 
ATOM   5002 N  N   . TYR A 1 634 ? 162.776 122.338 130.320 1.00 66.25  0  633 TYR A N   1 
ATOM   5003 C  CA  . TYR A 1 634 ? 161.966 121.127 130.247 1.00 66.25  0  633 TYR A CA  1 
ATOM   5004 C  C   . TYR A 1 634 ? 162.626 120.055 131.109 1.00 66.25  0  633 TYR A C   1 
ATOM   5005 O  O   . TYR A 1 634 ? 163.664 119.499 130.733 1.00 66.25  0  633 TYR A O   1 
ATOM   5006 C  CB  . TYR A 1 634 ? 161.818 120.686 128.791 1.00 66.25  0  633 TYR A CB  1 
ATOM   5007 C  CG  . TYR A 1 634 ? 161.126 119.361 128.571 1.00 66.25  0  633 TYR A CG  1 
ATOM   5008 C  CD1 . TYR A 1 634 ? 159.962 119.039 129.253 1.00 66.25  0  633 TYR A CD1 1 
ATOM   5009 C  CD2 . TYR A 1 634 ? 161.614 118.453 127.642 1.00 66.25  0  633 TYR A CD2 1 
ATOM   5010 C  CE1 . TYR A 1 634 ? 159.322 117.832 129.041 1.00 66.25  0  633 TYR A CE1 1 
ATOM   5011 C  CE2 . TYR A 1 634 ? 160.979 117.248 127.419 1.00 66.25  0  633 TYR A CE2 1 
ATOM   5012 C  CZ  . TYR A 1 634 ? 159.835 116.941 128.122 1.00 66.25  0  633 TYR A CZ  1 
ATOM   5013 O  OH  . TYR A 1 634 ? 159.201 115.741 127.905 1.00 66.25  0  633 TYR A OH  1 
ATOM   5014 N  N   . ILE A 1 635 ? 162.022 119.770 132.263 1.00 65.73  0  634 ILE A N   1 
ATOM   5015 C  CA  . ILE A 1 635 ? 162.585 118.865 133.259 1.00 65.73  0  634 ILE A CA  1 
ATOM   5016 C  C   . ILE A 1 635 ? 162.160 117.438 132.939 1.00 65.73  0  634 ILE A C   1 
ATOM   5017 O  O   . ILE A 1 635 ? 161.025 117.192 132.516 1.00 65.73  0  634 ILE A O   1 
ATOM   5018 C  CB  . ILE A 1 635 ? 162.149 119.275 134.681 1.00 65.73  0  634 ILE A CB  1 
ATOM   5019 C  CG1 . ILE A 1 635 ? 162.677 120.667 135.038 1.00 65.73  0  634 ILE A CG1 1 
ATOM   5020 C  CG2 . ILE A 1 635 ? 162.624 118.263 135.715 1.00 65.73  0  634 ILE A CG2 1 
ATOM   5021 C  CD1 . ILE A 1 635 ? 161.762 121.807 134.647 1.00 65.73  0  634 ILE A CD1 1 
ATOM   5022 N  N   . GLN A 1 636 ? 163.076 116.491 133.141 1.00 67.99  0  635 GLN A N   1 
ATOM   5023 C  CA  . GLN A 1 636 ? 162.850 115.081 132.824 1.00 67.99  0  635 GLN A CA  1 
ATOM   5024 C  C   . GLN A 1 636 ? 162.526 114.250 134.059 1.00 67.99  0  635 GLN A C   1 
ATOM   5025 O  O   . GLN A 1 636 ? 162.885 113.072 134.131 1.00 67.99  0  635 GLN A O   1 
ATOM   5026 C  CB  . GLN A 1 636 ? 164.063 114.504 132.102 1.00 67.99  0  635 GLN A CB  1 
ATOM   5027 C  CG  . GLN A 1 636 ? 164.450 115.243 130.832 1.00 67.99  0  635 GLN A CG  1 
ATOM   5028 C  CD  . GLN A 1 636 ? 163.312 115.334 129.839 1.00 67.99  0  635 GLN A CD  1 
ATOM   5029 O  OE1 . GLN A 1 636 ? 163.144 114.463 128.986 1.00 67.99  0  635 GLN A OE1 1 
ATOM   5030 N  NE2 . GLN A 1 636 ? 162.526 116.399 129.938 1.00 67.99  0  635 GLN A NE2 1 
ATOM   5031 N  N   . ALA A 1 637 ? 161.853 114.831 135.048 1.00 69.16  0  636 ALA A N   1 
ATOM   5032 C  CA  . ALA A 1 637 ? 161.433 114.071 136.214 1.00 69.16  0  636 ALA A CA  1 
ATOM   5033 C  C   . ALA A 1 637 ? 160.218 113.212 135.867 1.00 69.16  0  636 ALA A C   1 
ATOM   5034 O  O   . ALA A 1 637 ? 159.725 113.214 134.735 1.00 69.16  0  636 ALA A O   1 
ATOM   5035 C  CB  . ALA A 1 637 ? 161.134 115.008 137.381 1.00 69.16  0  636 ALA A CB  1 
ATOM   5036 N  N   . LYS A 1 638 ? 159.731 112.456 136.852 1.00 70.91  0  637 LYS A N   1 
ATOM   5037 C  CA  . LYS A 1 638 ? 158.530 111.653 136.630 1.00 70.91  0  637 LYS A CA  1 
ATOM   5038 C  C   . LYS A 1 638 ? 157.324 112.513 136.270 1.00 70.91  0  637 LYS A C   1 
ATOM   5039 O  O   . LYS A 1 638 ? 156.634 112.186 135.289 1.00 70.91  0  637 LYS A O   1 
ATOM   5040 C  CB  . LYS A 1 638 ? 158.258 110.771 137.854 1.00 70.91  0  637 LYS A CB  1 
ATOM   5041 C  CG  . LYS A 1 638 ? 159.433 109.901 138.269 1.00 70.91  0  637 LYS A CG  1 
ATOM   5042 C  CD  . LYS A 1 638 ? 159.653 108.762 137.288 1.00 70.91  0  637 LYS A CD  1 
ATOM   5043 C  CE  . LYS A 1 638 ? 160.717 107.802 137.793 1.00 70.91  0  637 LYS A CE  1 
ATOM   5044 N  NZ  . LYS A 1 638 ? 160.960 106.688 136.835 1.00 70.91  1  637 LYS A NZ  1 
ATOM   5045 N  N   . PRO A 1 639 ? 157.004 113.604 136.994 1.00 67.66  0  638 PRO A N   1 
ATOM   5046 C  CA  . PRO A 1 639 ? 155.991 114.552 136.484 1.00 67.66  0  638 PRO A CA  1 
ATOM   5047 C  C   . PRO A 1 639 ? 156.621 115.618 135.586 1.00 67.66  0  638 PRO A C   1 
ATOM   5048 O  O   . PRO A 1 639 ? 156.936 116.735 136.003 1.00 67.66  0  638 PRO A O   1 
ATOM   5049 C  CB  . PRO A 1 639 ? 155.407 115.142 137.767 1.00 67.66  0  638 PRO A CB  1 
ATOM   5050 C  CG  . PRO A 1 639 ? 156.545 115.127 138.725 1.00 67.66  0  638 PRO A CG  1 
ATOM   5051 C  CD  . PRO A 1 639 ? 157.465 113.992 138.341 1.00 67.66  0  638 PRO A CD  1 
ATOM   5052 N  N   . SER A 1 640 ? 156.836 115.246 134.322 1.00 67.85  0  639 SER A N   1 
ATOM   5053 C  CA  . SER A 1 640 ? 157.517 116.105 133.357 1.00 67.85  0  639 SER A CA  1 
ATOM   5054 C  C   . SER A 1 640 ? 156.914 117.502 133.344 1.00 67.85  0  639 SER A C   1 
ATOM   5055 O  O   . SER A 1 640 ? 155.700 117.666 133.188 1.00 67.85  0  639 SER A O   1 
ATOM   5056 C  CB  . SER A 1 640 ? 157.441 115.481 131.963 1.00 67.85  0  639 SER A CB  1 
ATOM   5057 O  OG  . SER A 1 640 ? 157.984 114.172 131.962 1.00 67.85  0  639 SER A OG  1 
ATOM   5058 N  N   . ARG A 1 641 ? 157.769 118.504 133.508 1.00 65.42  0  640 ARG A N   1 
ATOM   5059 C  CA  . ARG A 1 641 ? 157.352 119.873 133.764 1.00 65.42  0  640 ARG A CA  1 
ATOM   5060 C  C   . ARG A 1 641 ? 157.815 120.791 132.639 1.00 65.42  0  640 ARG A C   1 
ATOM   5061 O  O   . ARG A 1 641 ? 158.367 120.355 131.625 1.00 65.42  0  640 ARG A O   1 
ATOM   5062 C  CB  . ARG A 1 641 ? 157.912 120.358 135.102 1.00 65.42  0  640 ARG A CB  1 
ATOM   5063 C  CG  . ARG A 1 641 ? 156.975 120.204 136.278 1.00 65.42  0  640 ARG A CG  1 
ATOM   5064 C  CD  . ARG A 1 641 ? 157.709 120.514 137.567 1.00 65.42  0  640 ARG A CD  1 
ATOM   5065 N  NE  . ARG A 1 641 ? 158.864 119.646 137.759 1.00 65.42  0  640 ARG A NE  1 
ATOM   5066 C  CZ  . ARG A 1 641 ? 158.875 118.571 138.533 1.00 65.42  0  640 ARG A CZ  1 
ATOM   5067 N  NH1 . ARG A 1 641 ? 157.803 118.194 139.207 1.00 65.42  1  640 ARG A NH1 1 
ATOM   5068 N  NH2 . ARG A 1 641 ? 159.993 117.858 138.636 1.00 65.42  0  640 ARG A NH2 1 
ATOM   5069 N  N   . LEU A 1 642 ? 157.579 122.087 132.838 1.00 65.67  0  641 LEU A N   1 
ATOM   5070 C  CA  . LEU A 1 642 ? 158.090 123.125 131.944 1.00 65.67  0  641 LEU A CA  1 
ATOM   5071 C  C   . LEU A 1 642 ? 158.191 124.396 132.783 1.00 65.67  0  641 LEU A C   1 
ATOM   5072 O  O   . LEU A 1 642 ? 157.181 125.063 133.026 1.00 65.67  0  641 LEU A O   1 
ATOM   5073 C  CB  . LEU A 1 642 ? 157.184 123.303 130.734 1.00 65.67  0  641 LEU A CB  1 
ATOM   5074 C  CG  . LEU A 1 642 ? 157.629 124.284 129.652 1.00 65.67  0  641 LEU A CG  1 
ATOM   5075 C  CD1 . LEU A 1 642 ? 158.939 123.830 129.034 1.00 65.67  0  641 LEU A CD1 1 
ATOM   5076 C  CD2 . LEU A 1 642 ? 156.554 124.394 128.588 1.00 65.67  0  641 LEU A CD2 1 
ATOM   5077 N  N   . HIS A 1 643 ? 159.405 124.719 133.221 1.00 65.05  0  642 HIS A N   1 
ATOM   5078 C  CA  . HIS A 1 643 ? 159.638 125.719 134.254 1.00 65.05  0  642 HIS A CA  1 
ATOM   5079 C  C   . HIS A 1 643 ? 160.179 127.005 133.647 1.00 65.05  0  642 HIS A C   1 
ATOM   5080 O  O   . HIS A 1 643 ? 161.081 126.969 132.803 1.00 65.05  0  642 HIS A O   1 
ATOM   5081 C  CB  . HIS A 1 643 ? 160.614 125.186 135.305 1.00 65.05  0  642 HIS A CB  1 
ATOM   5082 C  CG  . HIS A 1 643 ? 160.963 126.178 136.369 1.00 65.05  0  642 HIS A CG  1 
ATOM   5083 N  ND1 . HIS A 1 643 ? 160.009 126.844 137.107 1.00 65.05  0  642 HIS A ND1 1 
ATOM   5084 C  CD2 . HIS A 1 643 ? 162.162 126.613 136.824 1.00 65.05  0  642 HIS A CD2 1 
ATOM   5085 C  CE1 . HIS A 1 643 ? 160.604 127.650 137.968 1.00 65.05  0  642 HIS A CE1 1 
ATOM   5086 N  NE2 . HIS A 1 643 ? 161.911 127.528 137.816 1.00 65.05  0  642 HIS A NE2 1 
ATOM   5087 N  N   . CYS A 1 644 ? 159.626 128.136 134.078 1.00 67.02  0  643 CYS A N   1 
ATOM   5088 C  CA  . CYS A 1 644 ? 160.127 129.454 133.711 1.00 67.02  0  643 CYS A CA  1 
ATOM   5089 C  C   . CYS A 1 644 ? 160.867 130.052 134.900 1.00 67.02  0  643 CYS A C   1 
ATOM   5090 O  O   . CYS A 1 644 ? 160.316 130.133 136.002 1.00 67.02  0  643 CYS A O   1 
ATOM   5091 C  CB  . CYS A 1 644 ? 158.986 130.377 133.279 1.00 67.02  0  643 CYS A CB  1 
ATOM   5092 S  SG  . CYS A 1 644 ? 159.523 131.968 132.600 1.00 67.02  0  643 CYS A SG  1 
ATOM   5093 N  N   . SER A 1 645 ? 162.118 130.456 134.677 1.00 65.42  0  644 SER A N   1 
ATOM   5094 C  CA  . SER A 1 645 ? 162.911 131.033 135.755 1.00 65.42  0  644 SER A CA  1 
ATOM   5095 C  C   . SER A 1 645 ? 162.511 132.470 136.061 1.00 65.42  0  644 SER A C   1 
ATOM   5096 O  O   . SER A 1 645 ? 162.556 132.884 137.225 1.00 65.42  0  644 SER A O   1 
ATOM   5097 C  CB  . SER A 1 645 ? 164.398 130.966 135.406 1.00 65.42  0  644 SER A CB  1 
ATOM   5098 O  OG  . SER A 1 645 ? 164.767 129.657 135.009 1.00 65.42  0  644 SER A OG  1 
ATOM   5099 N  N   . HIS A 1 646 ? 162.129 133.242 135.041 1.00 64.68  0  645 HIS A N   1 
ATOM   5100 C  CA  . HIS A 1 646 ? 161.767 134.640 135.253 1.00 64.68  0  645 HIS A CA  1 
ATOM   5101 C  C   . HIS A 1 646 ? 160.547 134.758 136.160 1.00 64.68  0  645 HIS A C   1 
ATOM   5102 O  O   . HIS A 1 646 ? 160.626 135.310 137.263 1.00 64.68  0  645 HIS A O   1 
ATOM   5103 C  CB  . HIS A 1 646 ? 161.515 135.320 133.907 1.00 64.68  0  645 HIS A CB  1 
ATOM   5104 C  CG  . HIS A 1 646 ? 161.851 136.778 133.893 1.00 64.68  0  645 HIS A CG  1 
ATOM   5105 N  ND1 . HIS A 1 646 ? 160.896 137.764 134.015 1.00 64.68  0  645 HIS A ND1 1 
ATOM   5106 C  CD2 . HIS A 1 646 ? 163.037 137.418 133.768 1.00 64.68  0  645 HIS A CD2 1 
ATOM   5107 C  CE1 . HIS A 1 646 ? 161.480 138.948 133.967 1.00 64.68  0  645 HIS A CE1 1 
ATOM   5108 N  NE2 . HIS A 1 646 ? 162.779 138.766 133.818 1.00 64.68  0  645 HIS A NE2 1 
ATOM   5109 N  N   . CYS A 1 647 ? 159.408 134.241 135.711 1.00 68.39  0  646 CYS A N   1 
ATOM   5110 C  CA  . CYS A 1 647 ? 158.210 134.154 136.536 1.00 68.39  0  646 CYS A CA  1 
ATOM   5111 C  C   . CYS A 1 647 ? 158.152 132.757 137.139 1.00 68.39  0  646 CYS A C   1 
ATOM   5112 O  O   . CYS A 1 647 ? 158.154 131.760 136.408 1.00 68.39  0  646 CYS A O   1 
ATOM   5113 C  CB  . CYS A 1 647 ? 156.949 134.467 135.725 1.00 68.39  0  646 CYS A CB  1 
ATOM   5114 S  SG  . CYS A 1 647 ? 156.546 133.320 134.376 1.00 68.39  0  646 CYS A SG  1 
ATOM   5115 N  N   . ASP A 1 648 ? 158.106 132.684 138.468 1.00 65.40  0  647 ASP A N   1 
ATOM   5116 C  CA  . ASP A 1 648 ? 158.211 131.398 139.146 1.00 65.40  0  647 ASP A CA  1 
ATOM   5117 C  C   . ASP A 1 648 ? 156.926 130.598 138.988 1.00 65.40  0  647 ASP A C   1 
ATOM   5118 O  O   . ASP A 1 648 ? 156.124 130.501 139.922 1.00 65.40  0  647 ASP A O   1 
ATOM   5119 C  CB  . ASP A 1 648 ? 158.542 131.598 140.625 1.00 65.40  0  647 ASP A CB  1 
ATOM   5120 C  CG  . ASP A 1 648 ? 159.961 132.083 140.843 1.00 65.40  0  647 ASP A CG  1 
ATOM   5121 O  OD1 . ASP A 1 648 ? 160.837 131.751 140.017 1.00 65.40  0  647 ASP A OD1 1 
ATOM   5122 O  OD2 . ASP A 1 648 ? 160.202 132.797 141.839 1.00 65.40  -1 647 ASP A OD2 1 
ATOM   5123 N  N   . GLU A 1 649 ? 156.729 130.022 137.805 1.00 67.45  0  648 GLU A N   1 
ATOM   5124 C  CA  . GLU A 1 649 ? 155.563 129.205 137.515 1.00 67.45  0  648 GLU A CA  1 
ATOM   5125 C  C   . GLU A 1 649 ? 156.006 127.958 136.767 1.00 67.45  0  648 GLU A C   1 
ATOM   5126 O  O   . GLU A 1 649 ? 156.993 127.976 136.028 1.00 67.45  0  648 GLU A O   1 
ATOM   5127 C  CB  . GLU A 1 649 ? 154.525 129.976 136.689 1.00 67.45  0  648 GLU A CB  1 
ATOM   5128 C  CG  . GLU A 1 649 ? 153.419 130.607 137.517 1.00 67.45  0  648 GLU A CG  1 
ATOM   5129 C  CD  . GLU A 1 649 ? 152.476 131.450 136.682 1.00 67.45  0  648 GLU A CD  1 
ATOM   5130 O  OE1 . GLU A 1 649 ? 152.725 131.595 135.467 1.00 67.45  0  648 GLU A OE1 1 
ATOM   5131 O  OE2 . GLU A 1 649 ? 151.486 131.967 137.241 1.00 67.45  -1 648 GLU A OE2 1 
ATOM   5132 N  N   . THR A 1 650 ? 155.265 126.872 136.966 1.00 66.89  0  649 THR A N   1 
ATOM   5133 C  CA  . THR A 1 650 ? 155.538 125.609 136.299 1.00 66.89  0  649 THR A CA  1 
ATOM   5134 C  C   . THR A 1 650 ? 154.284 125.131 135.583 1.00 66.89  0  649 THR A C   1 
ATOM   5135 O  O   . THR A 1 650 ? 153.159 125.435 135.992 1.00 66.89  0  649 THR A O   1 
ATOM   5136 C  CB  . THR A 1 650 ? 156.025 124.537 137.286 1.00 66.89  0  649 THR A CB  1 
ATOM   5137 O  OG1 . THR A 1 650 ? 156.429 123.369 136.561 1.00 66.89  0  649 THR A OG1 1 
ATOM   5138 C  CG2 . THR A 1 650 ? 154.926 124.165 138.270 1.00 66.89  0  649 THR A CG2 1 
ATOM   5139 N  N   . TYR A 1 651 ? 154.489 124.389 134.498 1.00 70.44  0  650 TYR A N   1 
ATOM   5140 C  CA  . TYR A 1 651 ? 153.399 123.898 133.667 1.00 70.44  0  650 TYR A CA  1 
ATOM   5141 C  C   . TYR A 1 651 ? 153.567 122.402 133.449 1.00 70.44  0  650 TYR A C   1 
ATOM   5142 O  O   . TYR A 1 651 ? 154.657 121.941 133.097 1.00 70.44  0  650 TYR A O   1 
ATOM   5143 C  CB  . TYR A 1 651 ? 153.357 124.641 132.330 1.00 70.44  0  650 TYR A CB  1 
ATOM   5144 C  CG  . TYR A 1 651 ? 153.293 126.142 132.488 1.00 70.44  0  650 TYR A CG  1 
ATOM   5145 C  CD1 . TYR A 1 651 ? 152.242 126.742 133.167 1.00 70.44  0  650 TYR A CD1 1 
ATOM   5146 C  CD2 . TYR A 1 651 ? 154.287 126.959 131.970 1.00 70.44  0  650 TYR A CD2 1 
ATOM   5147 C  CE1 . TYR A 1 651 ? 152.179 128.112 133.319 1.00 70.44  0  650 TYR A CE1 1 
ATOM   5148 C  CE2 . TYR A 1 651 ? 154.232 128.331 132.118 1.00 70.44  0  650 TYR A CE2 1 
ATOM   5149 C  CZ  . TYR A 1 651 ? 153.176 128.902 132.794 1.00 70.44  0  650 TYR A CZ  1 
ATOM   5150 O  OH  . TYR A 1 651 ? 153.116 130.268 132.943 1.00 70.44  0  650 TYR A OH  1 
ATOM   5151 N  N   . THR A 1 652 ? 152.488 121.654 133.659 1.00 73.88  0  651 THR A N   1 
ATOM   5152 C  CA  . THR A 1 652 ? 152.517 120.201 133.568 1.00 73.88  0  651 THR A CA  1 
ATOM   5153 C  C   . THR A 1 652 ? 152.289 119.756 132.129 1.00 73.88  0  651 THR A C   1 
ATOM   5154 O  O   . THR A 1 652 ? 151.470 120.335 131.409 1.00 73.88  0  651 THR A O   1 
ATOM   5155 C  CB  . THR A 1 652 ? 151.455 119.590 134.487 1.00 73.88  0  651 THR A CB  1 
ATOM   5156 O  OG1 . THR A 1 652 ? 151.714 119.978 135.841 1.00 73.88  0  651 THR A OG1 1 
ATOM   5157 C  CG2 . THR A 1 652 ? 151.467 118.069 134.399 1.00 73.88  0  651 THR A CG2 1 
ATOM   5158 N  N   . LEU A 1 653 ? 153.018 118.729 131.718 1.00 74.67  0  652 LEU A N   1 
ATOM   5159 C  CA  . LEU A 1 653 ? 152.940 118.156 130.385 1.00 74.67  0  652 LEU A CA  1 
ATOM   5160 C  C   . LEU A 1 653 ? 152.637 116.671 130.494 1.00 74.67  0  652 LEU A C   1 
ATOM   5161 O  O   . LEU A 1 653 ? 152.914 116.047 131.524 1.00 74.67  0  652 LEU A O   1 
ATOM   5162 C  CB  . LEU A 1 653 ? 154.251 118.371 129.614 1.00 74.67  0  652 LEU A CB  1 
ATOM   5163 C  CG  . LEU A 1 653 ? 154.630 119.823 129.321 1.00 74.67  0  652 LEU A CG  1 
ATOM   5164 C  CD1 . LEU A 1 653 ? 155.875 119.886 128.453 1.00 74.67  0  652 LEU A CD1 1 
ATOM   5165 C  CD2 . LEU A 1 653 ? 153.476 120.559 128.662 1.00 74.67  0  652 LEU A CD2 1 
ATOM   5166 N  N   . PRO A 1 654 ? 152.055 116.075 129.451 1.00 78.06  0  653 PRO A N   1 
ATOM   5167 C  CA  . PRO A 1 654 ? 151.717 114.648 129.514 1.00 78.06  0  653 PRO A CA  1 
ATOM   5168 C  C   . PRO A 1 654 ? 152.956 113.780 129.670 1.00 78.06  0  653 PRO A C   1 
ATOM   5169 O  O   . PRO A 1 654 ? 154.052 114.132 129.230 1.00 78.06  0  653 PRO A O   1 
ATOM   5170 C  CB  . PRO A 1 654 ? 151.021 114.388 128.173 1.00 78.06  0  653 PRO A CB  1 
ATOM   5171 C  CG  . PRO A 1 654 ? 150.532 115.721 127.737 1.00 78.06  0  653 PRO A CG  1 
ATOM   5172 C  CD  . PRO A 1 654 ? 151.558 116.700 128.215 1.00 78.06  0  653 PRO A CD  1 
ATOM   5173 N  N   . ASN A 1 655 ? 152.766 112.634 130.314 1.00 78.83  0  654 ASN A N   1 
ATOM   5174 C  CA  . ASN A 1 655 ? 153.836 111.688 130.589 1.00 78.83  0  654 ASN A CA  1 
ATOM   5175 C  C   . ASN A 1 655 ? 153.720 110.480 129.669 1.00 78.83  0  654 ASN A C   1 
ATOM   5176 O  O   . ASN A 1 655 ? 152.712 110.282 128.986 1.00 78.83  0  654 ASN A O   1 
ATOM   5177 C  CB  . ASN A 1 655 ? 153.807 111.253 132.058 1.00 78.83  0  654 ASN A CB  1 
ATOM   5178 C  CG  . ASN A 1 655 ? 153.628 112.422 133.007 1.00 78.83  0  654 ASN A CG  1 
ATOM   5179 O  OD1 . ASN A 1 655 ? 154.600 112.988 133.503 1.00 78.83  0  654 ASN A OD1 1 
ATOM   5180 N  ND2 . ASN A 1 655 ? 152.378 112.787 133.266 1.00 78.83  0  654 ASN A ND2 1 
ATOM   5181 N  N   . ASN A 1 656 ? 154.773 109.659 129.679 1.00 82.44  0  655 ASN A N   1 
ATOM   5182 C  CA  . ASN A 1 656 ? 154.912 108.509 128.783 1.00 82.44  0  655 ASN A CA  1 
ATOM   5183 C  C   . ASN A 1 656 ? 154.943 108.960 127.320 1.00 82.44  0  655 ASN A C   1 
ATOM   5184 O  O   . ASN A 1 656 ? 154.093 108.596 126.504 1.00 82.44  0  655 ASN A O   1 
ATOM   5185 C  CB  . ASN A 1 656 ? 153.804 107.476 129.025 1.00 82.44  0  655 ASN A CB  1 
ATOM   5186 C  CG  . ASN A 1 656 ? 153.953 106.762 130.353 1.00 82.44  0  655 ASN A CG  1 
ATOM   5187 O  OD1 . ASN A 1 656 ? 155.056 106.391 130.752 1.00 82.44  0  655 ASN A OD1 1 
ATOM   5188 N  ND2 . ASN A 1 656 ? 152.837 106.565 131.046 1.00 82.44  0  655 ASN A ND2 1 
ATOM   5189 N  N   . GLY A 1 657 ? 155.949 109.769 127.005 1.00 81.51  0  656 GLY A N   1 
ATOM   5190 C  CA  . GLY A 1 657 ? 156.129 110.242 125.645 1.00 81.51  0  656 GLY A CA  1 
ATOM   5191 C  C   . GLY A 1 657 ? 157.235 111.276 125.581 1.00 81.51  0  656 GLY A C   1 
ATOM   5192 O  O   . GLY A 1 657 ? 158.047 111.392 126.501 1.00 81.51  0  656 GLY A O   1 
ATOM   5193 N  N   . THR A 1 658 ? 157.252 112.025 124.479 1.00 81.35  0  657 THR A N   1 
ATOM   5194 C  CA  . THR A 1 658 ? 158.264 113.044 124.241 1.00 81.35  0  657 THR A CA  1 
ATOM   5195 C  C   . THR A 1 658 ? 157.598 114.367 123.890 1.00 81.35  0  657 THR A C   1 
ATOM   5196 O  O   . THR A 1 658 ? 156.458 114.404 123.420 1.00 81.35  0  657 THR A O   1 
ATOM   5197 C  CB  . THR A 1 658 ? 159.229 112.645 123.110 1.00 81.35  0  657 THR A CB  1 
ATOM   5198 O  OG1 . THR A 1 658 ? 158.570 112.779 121.845 1.00 81.35  0  657 THR A OG1 1 
ATOM   5199 C  CG2 . THR A 1 658 ? 159.705 111.208 123.281 1.00 81.35  0  657 THR A CG2 1 
ATOM   5200 N  N   . ILE A 1 659 ? 158.329 115.455 124.125 1.00 77.20  0  658 ILE A N   1 
ATOM   5201 C  CA  . ILE A 1 659 ? 157.877 116.808 123.823 1.00 77.20  0  658 ILE A CA  1 
ATOM   5202 C  C   . ILE A 1 659 ? 158.843 117.425 122.822 1.00 77.20  0  658 ILE A C   1 
ATOM   5203 O  O   . ILE A 1 659 ? 160.062 117.399 123.028 1.00 77.20  0  658 ILE A O   1 
ATOM   5204 C  CB  . ILE A 1 659 ? 157.784 117.669 125.095 1.00 77.20  0  658 ILE A CB  1 
ATOM   5205 C  CG1 . ILE A 1 659 ? 156.764 117.079 126.069 1.00 77.20  0  658 ILE A CG1 1 
ATOM   5206 C  CG2 . ILE A 1 659 ? 157.420 119.100 124.746 1.00 77.20  0  658 ILE A CG2 1 
ATOM   5207 C  CD1 . ILE A 1 659 ? 155.406 116.853 125.456 1.00 77.20  0  658 ILE A CD1 1 
ATOM   5208 N  N   . LYS A 1 660 ? 158.300 117.978 121.740 1.00 79.68  0  659 LYS A N   1 
ATOM   5209 C  CA  . LYS A 1 660 ? 159.099 118.626 120.712 1.00 79.68  0  659 LYS A CA  1 
ATOM   5210 C  C   . LYS A 1 660 ? 158.427 119.926 120.299 1.00 79.68  0  659 LYS A C   1 
ATOM   5211 O  O   . LYS A 1 660 ? 157.213 120.089 120.444 1.00 79.68  0  659 LYS A O   1 
ATOM   5212 C  CB  . LYS A 1 660 ? 159.291 117.720 119.489 1.00 79.68  0  659 LYS A CB  1 
ATOM   5213 C  CG  . LYS A 1 660 ? 160.640 117.873 118.806 1.00 79.68  0  659 LYS A CG  1 
ATOM   5214 C  CD  . LYS A 1 660 ? 160.739 116.990 117.571 1.00 79.68  0  659 LYS A CD  1 
ATOM   5215 C  CE  . LYS A 1 660 ? 160.305 115.564 117.870 1.00 79.68  0  659 LYS A CE  1 
ATOM   5216 N  NZ  . LYS A 1 660 ? 160.236 114.737 116.633 1.00 79.68  1  659 LYS A NZ  1 
ATOM   5217 N  N   . LEU A 1 661 ? 159.231 120.853 119.786 1.00 81.77  0  660 LEU A N   1 
ATOM   5218 C  CA  . LEU A 1 661 ? 158.709 122.145 119.363 1.00 81.77  0  660 LEU A CA  1 
ATOM   5219 C  C   . LEU A 1 661 ? 157.840 121.994 118.120 1.00 81.77  0  660 LEU A C   1 
ATOM   5220 O  O   . LEU A 1 661 ? 158.207 121.305 117.164 1.00 81.77  0  660 LEU A O   1 
ATOM   5221 C  CB  . LEU A 1 661 ? 159.854 123.116 119.086 1.00 81.77  0  660 LEU A CB  1 
ATOM   5222 C  CG  . LEU A 1 661 ? 160.686 123.545 120.295 1.00 81.77  0  660 LEU A CG  1 
ATOM   5223 C  CD1 . LEU A 1 661 ? 161.868 124.397 119.862 1.00 81.77  0  660 LEU A CD1 1 
ATOM   5224 C  CD2 . LEU A 1 661 ? 159.823 124.290 121.299 1.00 81.77  0  660 LEU A CD2 1 
ATOM   5225 N  N   . TYR A 1 662 ? 156.776 122.809 118.060 1.00 85.89  0  661 TYR A N   1 
ATOM   5226 C  CA  . TYR A 1 662 ? 155.818 122.746 116.922 1.00 85.89  0  661 TYR A CA  1 
ATOM   5227 C  C   . TYR A 1 662 ? 155.995 123.920 115.952 1.00 85.89  0  661 TYR A C   1 
ATOM   5228 O  O   . TYR A 1 662 ? 155.063 124.742 115.859 1.00 85.89  0  661 TYR A O   1 
ATOM   5229 C  CB  . TYR A 1 662 ? 154.382 122.749 117.449 1.00 85.89  0  661 TYR A CB  1 
ATOM   5230 C  CG  . TYR A 1 662 ? 153.346 122.221 116.490 1.00 85.89  0  661 TYR A CG  1 
ATOM   5231 C  CD1 . TYR A 1 662 ? 153.582 121.085 115.735 1.00 85.89  0  661 TYR A CD1 1 
ATOM   5232 C  CD2 . TYR A 1 662 ? 152.122 122.852 116.346 1.00 85.89  0  661 TYR A CD2 1 
ATOM   5233 C  CE1 . TYR A 1 662 ? 152.632 120.593 114.857 1.00 85.89  0  661 TYR A CE1 1 
ATOM   5234 C  CE2 . TYR A 1 662 ? 151.161 122.373 115.473 1.00 85.89  0  661 TYR A CE2 1 
ATOM   5235 C  CZ  . TYR A 1 662 ? 151.416 121.238 114.725 1.00 85.89  0  661 TYR A CZ  1 
ATOM   5236 O  OH  . TYR A 1 662 ? 150.474 120.761 113.861 1.00 85.89  0  661 TYR A OH  1 
ATOM   5237 N  N   . LYS A 1 663 ? 157.137 124.012 115.266 1.00 86.60  0  662 LYS A N   1 
ATOM   5238 C  CA  . LYS A 1 663 ? 157.335 125.041 114.203 1.00 86.60  0  662 LYS A CA  1 
ATOM   5239 C  C   . LYS A 1 663 ? 157.187 126.481 114.716 1.00 86.60  0  662 LYS A C   1 
ATOM   5240 O  O   . LYS A 1 663 ? 156.655 127.307 113.951 1.00 86.60  0  662 LYS A O   1 
ATOM   5241 C  CB  . LYS A 1 663 ? 156.378 124.777 113.036 1.00 86.60  0  662 LYS A CB  1 
ATOM   5242 C  CG  . LYS A 1 663 ? 156.648 123.500 112.251 1.00 86.60  0  662 LYS A CG  1 
ATOM   5243 C  CD  . LYS A 1 663 ? 155.662 123.271 111.125 1.00 86.60  0  662 LYS A CD  1 
ATOM   5244 C  CE  . LYS A 1 663 ? 155.949 122.014 110.333 1.00 86.60  0  662 LYS A CE  1 
ATOM   5245 N  NZ  . LYS A 1 663 ? 154.955 121.805 109.254 1.00 86.60  1  662 LYS A NZ  1 
ATOM   5246 N  N   . GLU A 1 664 ? 157.624 126.780 115.939 1.00 86.70  0  663 GLU A N   1 
ATOM   5247 C  CA  . GLU A 1 664 ? 157.658 128.188 116.437 1.00 86.70  0  663 GLU A CA  1 
ATOM   5248 C  C   . GLU A 1 664 ? 156.280 128.865 116.502 1.00 86.70  0  663 GLU A C   1 
ATOM   5249 O  O   . GLU A 1 664 ? 156.202 129.907 117.178 1.00 86.70  0  663 GLU A O   1 
ATOM   5250 C  CB  . GLU A 1 664 ? 158.600 129.022 115.566 1.00 86.70  0  663 GLU A CB  1 
ATOM   5251 C  CG  . GLU A 1 664 ? 160.039 128.543 115.603 1.00 86.70  0  663 GLU A CG  1 
ATOM   5252 C  CD  . GLU A 1 664 ? 160.300 127.270 114.817 1.00 86.70  0  663 GLU A CD  1 
ATOM   5253 O  OE1 . GLU A 1 664 ? 160.534 126.223 115.453 1.00 86.70  0  663 GLU A OE1 1 
ATOM   5254 O  OE2 . GLU A 1 664 ? 160.261 127.326 113.572 1.00 86.70  -1 663 GLU A OE2 1 
ATOM   5255 N  N   . LEU A 1 665 ? 155.249 128.347 115.826 1.00 85.16  0  664 LEU A N   1 
ATOM   5256 C  CA  . LEU A 1 665 ? 153.926 128.935 115.951 1.00 85.16  0  664 LEU A CA  1 
ATOM   5257 C  C   . LEU A 1 665 ? 153.608 129.234 117.416 1.00 85.16  0  664 LEU A C   1 
ATOM   5258 O  O   . LEU A 1 665 ? 154.263 128.747 118.342 1.00 85.16  0  664 LEU A O   1 
ATOM   5259 C  CB  . LEU A 1 665 ? 152.871 128.013 115.342 1.00 85.16  0  664 LEU A CB  1 
ATOM   5260 C  CG  . LEU A 1 665 ? 152.980 127.823 113.827 1.00 85.16  0  664 LEU A CG  1 
ATOM   5261 C  CD1 . LEU A 1 665 ? 151.981 126.787 113.336 1.00 85.16  0  664 LEU A CD1 1 
ATOM   5262 C  CD2 . LEU A 1 665 ? 152.786 129.148 113.102 1.00 85.16  0  664 LEU A CD2 1 
ATOM   5263 N  N   . ARG A 1 666 ? 152.582 130.057 117.616 1.00 84.21  0  665 ARG A N   1 
ATOM   5264 C  CA  . ARG A 1 666 ? 152.239 130.563 118.935 1.00 84.21  0  665 ARG A CA  1 
ATOM   5265 C  C   . ARG A 1 666 ? 150.731 130.493 119.129 1.00 84.21  0  665 ARG A C   1 
ATOM   5266 O  O   . ARG A 1 666 ? 149.953 130.681 118.190 1.00 84.21  0  665 ARG A O   1 
ATOM   5267 C  CB  . ARG A 1 666 ? 152.746 132.002 119.113 1.00 84.21  0  665 ARG A CB  1 
ATOM   5268 C  CG  . ARG A 1 666 ? 152.320 132.687 120.402 1.00 84.21  0  665 ARG A CG  1 
ATOM   5269 C  CD  . ARG A 1 666 ? 152.626 134.191 120.398 1.00 84.21  0  665 ARG A CD  1 
ATOM   5270 N  NE  . ARG A 1 666 ? 153.783 134.593 119.600 1.00 84.21  0  665 ARG A NE  1 
ATOM   5271 C  CZ  . ARG A 1 666 ? 155.029 134.175 119.788 1.00 84.21  0  665 ARG A CZ  1 
ATOM   5272 N  NH1 . ARG A 1 666 ? 155.348 133.364 120.783 1.00 84.21  1  665 ARG A NH1 1 
ATOM   5273 N  NH2 . ARG A 1 666 ? 155.985 134.597 118.964 1.00 84.21  0  665 ARG A NH2 1 
ATOM   5274 N  N   . CYS A 1 667 ? 150.326 130.217 120.364 1.00 86.48  0  666 CYS A N   1 
ATOM   5275 C  CA  . CYS A 1 667 ? 148.909 130.200 120.706 1.00 86.48  0  666 CYS A CA  1 
ATOM   5276 C  C   . CYS A 1 667 ? 148.349 131.617 120.649 1.00 86.48  0  666 CYS A C   1 
ATOM   5277 O  O   . CYS A 1 667 ? 148.965 132.542 121.189 1.00 86.48  0  666 CYS A O   1 
ATOM   5278 C  CB  . CYS A 1 667 ? 148.694 129.607 122.094 1.00 86.48  0  666 CYS A CB  1 
ATOM   5279 S  SG  . CYS A 1 667 ? 147.013 129.791 122.733 1.00 86.48  0  666 CYS A SG  1 
ATOM   5280 N  N   . PRO A 1 668 ? 147.195 131.827 120.015 1.00 88.45  0  667 PRO A N   1 
ATOM   5281 C  CA  . PRO A 1 668 ? 146.694 133.194 119.829 1.00 88.45  0  667 PRO A CA  1 
ATOM   5282 C  C   . PRO A 1 668 ? 145.862 133.698 120.999 1.00 88.45  0  667 PRO A C   1 
ATOM   5283 O  O   . PRO A 1 668 ? 145.142 134.692 120.862 1.00 88.45  0  667 PRO A O   1 
ATOM   5284 C  CB  . PRO A 1 668 ? 145.848 133.089 118.552 1.00 88.45  0  667 PRO A CB  1 
ATOM   5285 C  CG  . PRO A 1 668 ? 145.622 131.606 118.316 1.00 88.45  0  667 PRO A CG  1 
ATOM   5286 C  CD  . PRO A 1 668 ? 146.321 130.825 119.387 1.00 88.45  0  667 PRO A CD  1 
ATOM   5287 N  N   . LEU A 1 669 ? 145.946 133.030 122.148 1.00 88.66  0  668 LEU A N   1 
ATOM   5288 C  CA  . LEU A 1 669 ? 145.126 133.418 123.289 1.00 88.66  0  668 LEU A CA  1 
ATOM   5289 C  C   . LEU A 1 669 ? 146.003 133.751 124.491 1.00 88.66  0  668 LEU A C   1 
ATOM   5290 O  O   . LEU A 1 669 ? 145.718 134.700 125.228 1.00 88.66  0  668 LEU A O   1 
ATOM   5291 C  CB  . LEU A 1 669 ? 144.127 132.301 123.618 1.00 88.66  0  668 LEU A CB  1 
ATOM   5292 C  CG  . LEU A 1 669 ? 142.856 132.556 124.442 1.00 88.66  0  668 LEU A CG  1 
ATOM   5293 C  CD1 . LEU A 1 669 ? 142.001 131.300 124.447 1.00 88.66  0  668 LEU A CD1 1 
ATOM   5294 C  CD2 . LEU A 1 669 ? 143.132 132.995 125.874 1.00 88.66  0  668 LEU A CD2 1 
ATOM   5295 N  N   . ASP A 1 670 ? 147.104 133.010 124.675 1.00 85.80  0  669 ASP A N   1 
ATOM   5296 C  CA  . ASP A 1 670 ? 147.966 133.206 125.876 1.00 85.80  0  669 ASP A CA  1 
ATOM   5297 C  C   . ASP A 1 670 ? 149.389 133.622 125.481 1.00 85.80  0  669 ASP A C   1 
ATOM   5298 O  O   . ASP A 1 670 ? 150.183 133.888 126.403 1.00 85.80  0  669 ASP A O   1 
ATOM   5299 C  CB  . ASP A 1 670 ? 147.996 131.937 126.726 1.00 85.80  0  669 ASP A CB  1 
ATOM   5300 C  CG  . ASP A 1 670 ? 148.650 130.769 126.012 1.00 85.80  0  669 ASP A CG  1 
ATOM   5301 O  OD1 . ASP A 1 670 ? 149.229 130.995 124.933 1.00 85.80  0  669 ASP A OD1 1 
ATOM   5302 O  OD2 . ASP A 1 670 ? 148.564 129.644 126.536 1.00 85.80  -1 669 ASP A OD2 1 
ATOM   5303 N  N   . ASP A 1 671 ? 149.708 133.649 124.186 1.00 81.87  0  670 ASP A N   1 
ATOM   5304 C  CA  . ASP A 1 671 ? 151.018 134.070 123.694 1.00 81.87  0  670 ASP A CA  1 
ATOM   5305 C  C   . ASP A 1 671 ? 152.101 133.011 123.897 1.00 81.87  0  670 ASP A C   1 
ATOM   5306 O  O   . ASP A 1 671 ? 153.247 133.208 123.482 1.00 81.87  0  670 ASP A O   1 
ATOM   5307 C  CB  . ASP A 1 671 ? 151.443 135.402 124.331 1.00 81.87  0  670 ASP A CB  1 
ATOM   5308 C  CG  . ASP A 1 671 ? 152.652 136.019 123.657 1.00 81.87  0  670 ASP A CG  1 
ATOM   5309 O  OD1 . ASP A 1 671 ? 152.487 136.635 122.583 1.00 81.87  0  670 ASP A OD1 1 
ATOM   5310 O  OD2 . ASP A 1 671 ? 153.767 135.893 124.206 1.00 81.87  -1 670 ASP A OD2 1 
ATOM   5311 N  N   . PHE A 1 672 ? 151.770 131.880 124.508 1.00 79.30  0  671 PHE A N   1 
ATOM   5312 C  CA  . PHE A 1 672 ? 152.737 130.808 124.686 1.00 79.30  0  671 PHE A CA  1 
ATOM   5313 C  C   . PHE A 1 672 ? 153.016 130.109 123.360 1.00 79.30  0  671 PHE A C   1 
ATOM   5314 O  O   . PHE A 1 672 ? 152.185 130.091 122.448 1.00 79.30  0  671 PHE A O   1 
ATOM   5315 C  CB  . PHE A 1 672 ? 152.241 129.789 125.713 1.00 79.30  0  671 PHE A CB  1 
ATOM   5316 C  CG  . PHE A 1 672 ? 152.485 130.193 127.137 1.00 79.30  0  671 PHE A CG  1 
ATOM   5317 C  CD1 . PHE A 1 672 ? 151.648 131.094 127.770 1.00 79.30  0  671 PHE A CD1 1 
ATOM   5318 C  CD2 . PHE A 1 672 ? 153.554 129.671 127.843 1.00 79.30  0  671 PHE A CD2 1 
ATOM   5319 C  CE1 . PHE A 1 672 ? 151.871 131.465 129.080 1.00 79.30  0  671 PHE A CE1 1 
ATOM   5320 C  CE2 . PHE A 1 672 ? 153.783 130.039 129.152 1.00 79.30  0  671 PHE A CE2 1 
ATOM   5321 C  CZ  . PHE A 1 672 ? 152.940 130.937 129.771 1.00 79.30  0  671 PHE A CZ  1 
ATOM   5322 N  N   . GLU A 1 673 ? 154.208 129.527 123.262 1.00 78.95  0  672 GLU A N   1 
ATOM   5323 C  CA  . GLU A 1 673 ? 154.596 128.751 122.092 1.00 78.95  0  672 GLU A CA  1 
ATOM   5324 C  C   . GLU A 1 673 ? 154.175 127.303 122.303 1.00 78.95  0  672 GLU A C   1 
ATOM   5325 O  O   . GLU A 1 673 ? 154.622 126.653 123.254 1.00 78.95  0  672 GLU A O   1 
ATOM   5326 C  CB  . GLU A 1 673 ? 156.101 128.847 121.847 1.00 78.95  0  672 GLU A CB  1 
ATOM   5327 C  CG  . GLU A 1 673 ? 156.497 129.853 120.779 1.00 78.95  0  672 GLU A CG  1 
ATOM   5328 C  CD  . GLU A 1 673 ? 157.994 129.884 120.538 1.00 78.95  0  672 GLU A CD  1 
ATOM   5329 O  OE1 . GLU A 1 673 ? 158.724 129.146 121.233 1.00 78.95  0  672 GLU A OE1 1 
ATOM   5330 O  OE2 . GLU A 1 673 ? 158.440 130.647 119.656 1.00 78.95  -1 672 GLU A OE2 1 
ATOM   5331 N  N   . LEU A 1 674 ? 153.319 126.801 121.418 1.00 81.99  0  673 LEU A N   1 
ATOM   5332 C  CA  . LEU A 1 674 ? 152.769 125.463 121.572 1.00 81.99  0  673 LEU A CA  1 
ATOM   5333 C  C   . LEU A 1 674 ? 153.772 124.411 121.118 1.00 81.99  0  673 LEU A C   1 
ATOM   5334 O  O   . LEU A 1 674 ? 154.529 124.619 120.165 1.00 81.99  0  673 LEU A O   1 
ATOM   5335 C  CB  . LEU A 1 674 ? 151.462 125.323 120.788 1.00 81.99  0  673 LEU A CB  1 
ATOM   5336 C  CG  . LEU A 1 674 ? 151.483 125.241 119.259 1.00 81.99  0  673 LEU A CG  1 
ATOM   5337 C  CD1 . LEU A 1 674 ? 150.146 124.736 118.751 1.00 81.99  0  673 LEU A CD1 1 
ATOM   5338 C  CD2 . LEU A 1 674 ? 151.799 126.584 118.631 1.00 81.99  0  673 LEU A CD2 1 
ATOM   5339 N  N   . VAL A 1 675 ? 153.777 123.279 121.816 1.00 80.24  0  674 VAL A N   1 
ATOM   5340 C  CA  . VAL A 1 675 ? 154.678 122.172 121.531 1.00 80.24  0  674 VAL A CA  1 
ATOM   5341 C  C   . VAL A 1 675 ? 153.851 120.939 121.199 1.00 80.24  0  674 VAL A C   1 
ATOM   5342 O  O   . VAL A 1 675 ? 152.691 120.817 121.606 1.00 80.24  0  674 VAL A O   1 
ATOM   5343 C  CB  . VAL A 1 675 ? 155.628 121.891 122.714 1.00 80.24  0  674 VAL A CB  1 
ATOM   5344 C  CG1 . VAL A 1 675 ? 156.508 123.100 122.982 1.00 80.24  0  674 VAL A CG1 1 
ATOM   5345 C  CG2 . VAL A 1 675 ? 154.831 121.529 123.954 1.00 80.24  0  674 VAL A CG2 1 
ATOM   5346 N  N   . LEU A 1 676 ? 154.455 120.022 120.450 1.00 82.37  0  675 LEU A N   1 
ATOM   5347 C  CA  . LEU A 1 676 ? 153.774 118.801 120.050 1.00 82.37  0  675 LEU A CA  1 
ATOM   5348 C  C   . LEU A 1 676 ? 154.039 117.686 121.059 1.00 82.37  0  675 LEU A C   1 
ATOM   5349 O  O   . LEU A 1 676 ? 154.923 117.778 121.914 1.00 82.37  0  675 LEU A O   1 
ATOM   5350 C  CB  . LEU A 1 676 ? 154.203 118.384 118.640 1.00 82.37  0  675 LEU A CB  1 
ATOM   5351 C  CG  . LEU A 1 676 ? 155.667 118.038 118.349 1.00 82.37  0  675 LEU A CG  1 
ATOM   5352 C  CD1 . LEU A 1 676 ? 155.962 116.563 118.607 1.00 82.37  0  675 LEU A CD1 1 
ATOM   5353 C  CD2 . LEU A 1 676 ? 156.029 118.418 116.921 1.00 82.37  0  675 LEU A CD2 1 
ATOM   5354 N  N   . TRP A 1 677 ? 153.254 116.617 120.948 1.00 84.93  0  676 TRP A N   1 
ATOM   5355 C  CA  . TRP A 1 677 ? 153.301 115.496 121.885 1.00 84.93  0  676 TRP A CA  1 
ATOM   5356 C  C   . TRP A 1 677 ? 153.352 114.195 121.089 1.00 84.93  0  676 TRP A C   1 
ATOM   5357 O  O   . TRP A 1 677 ? 152.340 113.760 120.532 1.00 84.93  0  676 TRP A O   1 
ATOM   5358 C  CB  . TRP A 1 677 ? 152.099 115.527 122.824 1.00 84.93  0  676 TRP A CB  1 
ATOM   5359 C  CG  . TRP A 1 677 ? 151.765 114.203 123.432 1.00 84.93  0  676 TRP A CG  1 
ATOM   5360 C  CD1 . TRP A 1 677 ? 150.757 113.363 123.065 1.00 84.93  0  676 TRP A CD1 1 
ATOM   5361 C  CD2 . TRP A 1 677 ? 152.437 113.570 124.523 1.00 84.93  0  676 TRP A CD2 1 
ATOM   5362 N  NE1 . TRP A 1 677 ? 150.761 112.242 123.857 1.00 84.93  0  676 TRP A NE1 1 
ATOM   5363 C  CE2 . TRP A 1 677 ? 151.784 112.346 124.762 1.00 84.93  0  676 TRP A CE2 1 
ATOM   5364 C  CE3 . TRP A 1 677 ? 153.529 113.918 125.322 1.00 84.93  0  676 TRP A CE3 1 
ATOM   5365 C  CZ2 . TRP A 1 677 ? 152.186 111.470 125.763 1.00 84.93  0  676 TRP A CZ2 1 
ATOM   5366 C  CZ3 . TRP A 1 677 ? 153.927 113.049 126.314 1.00 84.93  0  676 TRP A CZ3 1 
ATOM   5367 C  CH2 . TRP A 1 677 ? 153.257 111.841 126.527 1.00 84.93  0  676 TRP A CH2 1 
ATOM   5368 N  N   . SER A 1 678 ? 154.530 113.578 121.029 1.00 85.42  0  677 SER A N   1 
ATOM   5369 C  CA  . SER A 1 678 ? 154.693 112.294 120.355 1.00 85.42  0  677 SER A CA  1 
ATOM   5370 C  C   . SER A 1 678 ? 154.316 111.183 121.327 1.00 85.42  0  677 SER A C   1 
ATOM   5371 O  O   . SER A 1 678 ? 155.017 110.948 122.316 1.00 85.42  0  677 SER A O   1 
ATOM   5372 C  CB  . SER A 1 678 ? 156.124 112.128 119.853 1.00 85.42  0  677 SER A CB  1 
ATOM   5373 O  OG  . SER A 1 678 ? 156.551 113.276 119.139 1.00 85.42  0  677 SER A OG  1 
ATOM   5374 N  N   . SER A 1 679 ? 153.208 110.499 121.047 1.00 88.90  0  678 SER A N   1 
ATOM   5375 C  CA  . SER A 1 679 ? 152.663 109.493 121.960 1.00 88.90  0  678 SER A CA  1 
ATOM   5376 C  C   . SER A 1 679 ? 153.296 108.129 121.680 1.00 88.90  0  678 SER A C   1 
ATOM   5377 O  O   . SER A 1 679 ? 152.678 107.211 121.137 1.00 88.90  0  678 SER A O   1 
ATOM   5378 C  CB  . SER A 1 679 ? 151.145 109.441 121.844 1.00 88.90  0  678 SER A CB  1 
ATOM   5379 O  OG  . SER A 1 679 ? 150.580 108.674 122.893 1.00 88.90  0  678 SER A OG  1 
ATOM   5380 N  N   . GLY A 1 680 ? 154.562 108.012 122.075 1.00 93.10  0  679 GLY A N   1 
ATOM   5381 C  CA  . GLY A 1 680 ? 155.262 106.743 122.018 1.00 93.10  0  679 GLY A CA  1 
ATOM   5382 C  C   . GLY A 1 680 ? 155.380 106.137 120.634 1.00 93.10  0  679 GLY A C   1 
ATOM   5383 O  O   . GLY A 1 680 ? 156.160 106.613 119.803 1.00 93.10  0  679 GLY A O   1 
ATOM   5384 N  N   . SER A 1 681 ? 154.617 105.073 120.389 1.00 97.08  0  680 SER A N   1 
ATOM   5385 C  CA  . SER A 1 681 ? 154.674 104.354 119.125 1.00 97.08  0  680 SER A CA  1 
ATOM   5386 C  C   . SER A 1 681 ? 154.365 105.280 117.950 1.00 97.08  0  680 SER A C   1 
ATOM   5387 O  O   . SER A 1 681 ? 153.807 106.370 118.107 1.00 97.08  0  680 SER A O   1 
ATOM   5388 C  CB  . SER A 1 681 ? 153.694 103.180 119.136 1.00 97.08  0  680 SER A CB  1 
ATOM   5389 O  OG  . SER A 1 681 ? 153.692 102.504 117.890 1.00 97.08  0  680 SER A OG  1 
ATOM   5390 N  N   . ARG A 1 682 ? 154.738 104.822 116.754 1.00 97.42  0  681 ARG A N   1 
ATOM   5391 C  CA  . ARG A 1 682 ? 154.588 105.617 115.541 1.00 97.42  0  681 ARG A CA  1 
ATOM   5392 C  C   . ARG A 1 682 ? 153.122 105.931 115.272 1.00 97.42  0  681 ARG A C   1 
ATOM   5393 O  O   . ARG A 1 682 ? 152.332 105.032 114.966 1.00 97.42  0  681 ARG A O   1 
ATOM   5394 C  CB  . ARG A 1 682 ? 155.201 104.887 114.342 1.00 97.42  0  681 ARG A CB  1 
ATOM   5395 C  CG  . ARG A 1 682 ? 156.705 104.633 114.437 1.00 97.42  0  681 ARG A CG  1 
ATOM   5396 C  CD  . ARG A 1 682 ? 157.434 105.713 115.227 1.00 97.42  0  681 ARG A CD  1 
ATOM   5397 N  NE  . ARG A 1 682 ? 157.414 107.004 114.550 1.00 97.42  0  681 ARG A NE  1 
ATOM   5398 C  CZ  . ARG A 1 682 ? 157.581 108.170 115.160 1.00 97.42  0  681 ARG A CZ  1 
ATOM   5399 N  NH1 . ARG A 1 682 ? 157.783 108.245 116.465 1.00 97.42  1  681 ARG A NH1 1 
ATOM   5400 N  NH2 . ARG A 1 682 ? 157.545 109.289 114.442 1.00 97.42  0  681 ARG A NH2 1 
ATOM   5401 N  N   . GLY A 1 683 ? 152.756 107.200 115.382 1.00 94.59  0  682 GLY A N   1 
ATOM   5402 C  CA  . GLY A 1 683 ? 151.376 107.588 115.184 1.00 94.59  0  682 GLY A CA  1 
ATOM   5403 C  C   . GLY A 1 683 ? 151.229 109.092 115.182 1.00 94.59  0  682 GLY A C   1 
ATOM   5404 O  O   . GLY A 1 683 ? 152.210 109.834 115.107 1.00 94.59  0  682 GLY A O   1 
ATOM   5405 N  N   . LYS A 1 684 ? 149.977 109.532 115.263 1.00 92.27  0  683 LYS A N   1 
ATOM   5406 C  CA  . LYS A 1 684 ? 149.678 110.955 115.224 1.00 92.27  0  683 LYS A CA  1 
ATOM   5407 C  C   . LYS A 1 684 ? 150.156 111.651 116.493 1.00 92.27  0  683 LYS A C   1 
ATOM   5408 O  O   . LYS A 1 684 ? 150.178 111.071 117.582 1.00 92.27  0  683 LYS A O   1 
ATOM   5409 C  CB  . LYS A 1 684 ? 148.176 111.179 115.043 1.00 92.27  0  683 LYS A CB  1 
ATOM   5410 C  CG  . LYS A 1 684 ? 147.315 110.472 116.076 1.00 92.27  0  683 LYS A CG  1 
ATOM   5411 C  CD  . LYS A 1 684 ? 145.982 110.046 115.484 1.00 92.27  0  683 LYS A CD  1 
ATOM   5412 C  CE  . LYS A 1 684 ? 146.115 108.749 114.703 1.00 92.27  0  683 LYS A CE  1 
ATOM   5413 N  NZ  . LYS A 1 684 ? 144.792 108.229 114.261 1.00 92.27  1  683 LYS A NZ  1 
ATOM   5414 N  N   . SER A 1 685 ? 150.549 112.913 116.337 1.00 91.20  0  684 SER A N   1 
ATOM   5415 C  CA  . SER A 1 685 ? 150.928 113.774 117.446 1.00 91.20  0  684 SER A CA  1 
ATOM   5416 C  C   . SER A 1 685 ? 150.080 115.034 117.396 1.00 91.20  0  684 SER A C   1 
ATOM   5417 O  O   . SER A 1 685 ? 149.895 115.621 116.325 1.00 91.20  0  684 SER A O   1 
ATOM   5418 C  CB  . SER A 1 685 ? 152.418 114.133 117.391 1.00 91.20  0  684 SER A CB  1 
ATOM   5419 O  OG  . SER A 1 685 ? 152.720 114.885 116.229 1.00 91.20  0  684 SER A OG  1 
ATOM   5420 N  N   . TYR A 1 686 ? 149.565 115.452 118.551 1.00 89.91  0  685 TYR A N   1 
ATOM   5421 C  CA  . TYR A 1 686 ? 148.669 116.595 118.546 1.00 89.91  0  685 TYR A CA  1 
ATOM   5422 C  C   . TYR A 1 686 ? 149.325 117.808 119.196 1.00 89.91  0  685 TYR A C   1 
ATOM   5423 O  O   . TYR A 1 686 ? 150.130 117.667 120.122 1.00 89.91  0  685 TYR A O   1 
ATOM   5424 C  CB  . TYR A 1 686 ? 147.350 116.282 119.268 1.00 89.91  0  685 TYR A CB  1 
ATOM   5425 C  CG  . TYR A 1 686 ? 147.500 115.712 120.662 1.00 89.91  0  685 TYR A CG  1 
ATOM   5426 C  CD1 . TYR A 1 686 ? 147.613 116.547 121.767 1.00 89.91  0  685 TYR A CD1 1 
ATOM   5427 C  CD2 . TYR A 1 686 ? 147.501 114.340 120.876 1.00 89.91  0  685 TYR A CD2 1 
ATOM   5428 C  CE1 . TYR A 1 686 ? 147.742 116.032 123.042 1.00 89.91  0  685 TYR A CE1 1 
ATOM   5429 C  CE2 . TYR A 1 686 ? 147.626 113.816 122.149 1.00 89.91  0  685 TYR A CE2 1 
ATOM   5430 C  CZ  . TYR A 1 686 ? 147.747 114.666 123.228 1.00 89.91  0  685 TYR A CZ  1 
ATOM   5431 O  OH  . TYR A 1 686 ? 147.874 114.149 124.496 1.00 89.91  0  685 TYR A OH  1 
ATOM   5432 N  N   . PRO A 1 687 ? 149.006 119.011 118.720 1.00 87.73  0  686 PRO A N   1 
ATOM   5433 C  CA  . PRO A 1 687 ? 149.547 120.225 119.343 1.00 87.73  0  686 PRO A CA  1 
ATOM   5434 C  C   . PRO A 1 687 ? 149.068 120.373 120.779 1.00 87.73  0  686 PRO A C   1 
ATOM   5435 O  O   . PRO A 1 687 ? 148.080 119.769 121.202 1.00 87.73  0  686 PRO A O   1 
ATOM   5436 C  CB  . PRO A 1 687 ? 149.013 121.364 118.465 1.00 87.73  0  686 PRO A CB  1 
ATOM   5437 C  CG  . PRO A 1 687 ? 148.289 120.743 117.332 1.00 87.73  0  686 PRO A CG  1 
ATOM   5438 C  CD  . PRO A 1 687 ? 148.356 119.261 117.424 1.00 87.73  0  686 PRO A CD  1 
ATOM   5439 N  N   . LEU A 1 688 ? 149.788 121.200 121.535 1.00 83.56  0  687 LEU A N   1 
ATOM   5440 C  CA  . LEU A 1 688 ? 149.502 121.364 122.957 1.00 83.56  0  687 LEU A CA  1 
ATOM   5441 C  C   . LEU A 1 688 ? 150.045 122.706 123.419 1.00 83.56  0  687 LEU A C   1 
ATOM   5442 O  O   . LEU A 1 688 ? 151.257 122.936 123.357 1.00 83.56  0  687 LEU A O   1 
ATOM   5443 C  CB  . LEU A 1 688 ? 150.118 120.216 123.760 1.00 83.56  0  687 LEU A CB  1 
ATOM   5444 C  CG  . LEU A 1 688 ? 149.808 120.073 125.250 1.00 83.56  0  687 LEU A CG  1 
ATOM   5445 C  CD1 . LEU A 1 688 ? 149.945 118.617 125.637 1.00 83.56  0  687 LEU A CD1 1 
ATOM   5446 C  CD2 . LEU A 1 688 ? 150.731 120.928 126.109 1.00 83.56  0  687 LEU A CD2 1 
ATOM   5447 N  N   . CYS A 1 689 ? 149.159 123.583 123.874 1.00 84.08  0  688 CYS A N   1 
ATOM   5448 C  CA  . CYS A 1 689 ? 149.580 124.844 124.471 1.00 84.08  0  688 CYS A CA  1 
ATOM   5449 C  C   . CYS A 1 689 ? 149.972 124.610 125.924 1.00 84.08  0  688 CYS A C   1 
ATOM   5450 O  O   . CYS A 1 689 ? 149.162 124.082 126.694 1.00 84.08  0  688 CYS A O   1 
ATOM   5451 C  CB  . CYS A 1 689 ? 148.466 125.878 124.387 1.00 84.08  0  688 CYS A CB  1 
ATOM   5452 S  SG  . CYS A 1 689 ? 148.781 127.390 125.323 1.00 84.08  0  688 CYS A SG  1 
ATOM   5453 N  N   . PRO A 1 690 ? 151.193 124.965 126.335 1.00 80.38  0  689 PRO A N   1 
ATOM   5454 C  CA  . PRO A 1 690 ? 151.603 124.696 127.724 1.00 80.38  0  689 PRO A CA  1 
ATOM   5455 C  C   . PRO A 1 690 ? 150.719 125.359 128.765 1.00 80.38  0  689 PRO A C   1 
ATOM   5456 O  O   . PRO A 1 690 ? 150.467 124.761 129.819 1.00 80.38  0  689 PRO A O   1 
ATOM   5457 C  CB  . PRO A 1 690 ? 153.037 125.241 127.779 1.00 80.38  0  689 PRO A CB  1 
ATOM   5458 C  CG  . PRO A 1 690 ? 153.492 125.302 126.362 1.00 80.38  0  689 PRO A CG  1 
ATOM   5459 C  CD  . PRO A 1 690 ? 152.274 125.559 125.533 1.00 80.38  0  689 PRO A CD  1 
ATOM   5460 N  N   . TYR A 1 691 ? 150.237 126.574 128.508 1.00 83.58  0  690 TYR A N   1 
ATOM   5461 C  CA  . TYR A 1 691 ? 149.401 127.275 129.473 1.00 83.58  0  690 TYR A CA  1 
ATOM   5462 C  C   . TYR A 1 691 ? 147.953 126.811 129.458 1.00 83.58  0  690 TYR A C   1 
ATOM   5463 O  O   . TYR A 1 691 ? 147.308 126.808 130.513 1.00 83.58  0  690 TYR A O   1 
ATOM   5464 C  CB  . TYR A 1 691 ? 149.451 128.784 129.220 1.00 83.58  0  690 TYR A CB  1 
ATOM   5465 C  CG  . TYR A 1 691 ? 148.832 129.612 130.323 1.00 83.58  0  690 TYR A CG  1 
ATOM   5466 C  CD1 . TYR A 1 691 ? 149.186 129.411 131.650 1.00 83.58  0  690 TYR A CD1 1 
ATOM   5467 C  CD2 . TYR A 1 691 ? 147.900 130.598 130.037 1.00 83.58  0  690 TYR A CD2 1 
ATOM   5468 C  CE1 . TYR A 1 691 ? 148.623 130.166 132.660 1.00 83.58  0  690 TYR A CE1 1 
ATOM   5469 C  CE2 . TYR A 1 691 ? 147.333 131.358 131.041 1.00 83.58  0  690 TYR A CE2 1 
ATOM   5470 C  CZ  . TYR A 1 691 ? 147.698 131.138 132.350 1.00 83.58  0  690 TYR A CZ  1 
ATOM   5471 O  OH  . TYR A 1 691 ? 147.135 131.894 133.352 1.00 83.58  0  690 TYR A OH  1 
ATOM   5472 N  N   . CYS A 1 692 ? 147.429 126.421 128.297 1.00 85.61  0  691 CYS A N   1 
ATOM   5473 C  CA  . CYS A 1 692 ? 146.061 125.930 128.209 1.00 85.61  0  691 CYS A CA  1 
ATOM   5474 C  C   . CYS A 1 692 ? 145.915 124.508 128.728 1.00 85.61  0  691 CYS A C   1 
ATOM   5475 O  O   . CYS A 1 692 ? 144.835 124.137 129.201 1.00 85.61  0  691 CYS A O   1 
ATOM   5476 C  CB  . CYS A 1 692 ? 145.566 126.002 126.762 1.00 85.61  0  691 CYS A CB  1 
ATOM   5477 S  SG  . CYS A 1 692 ? 145.895 127.579 125.941 1.00 85.61  0  691 CYS A SG  1 
ATOM   5478 N  N   . TYR A 1 693 ? 146.977 123.703 128.649 1.00 84.66  0  692 TYR A N   1 
ATOM   5479 C  CA  . TYR A 1 693 ? 146.932 122.350 129.189 1.00 84.66  0  692 TYR A CA  1 
ATOM   5480 C  C   . TYR A 1 693 ? 146.820 122.342 130.707 1.00 84.66  0  692 TYR A C   1 
ATOM   5481 O  O   . TYR A 1 693 ? 146.316 121.367 131.274 1.00 84.66  0  692 TYR A O   1 
ATOM   5482 C  CB  . TYR A 1 693 ? 148.173 121.572 128.751 1.00 84.66  0  692 TYR A CB  1 
ATOM   5483 C  CG  . TYR A 1 693 ? 148.107 120.086 129.022 1.00 84.66  0  692 TYR A CG  1 
ATOM   5484 C  CD1 . TYR A 1 693 ? 147.527 119.220 128.107 1.00 84.66  0  692 TYR A CD1 1 
ATOM   5485 C  CD2 . TYR A 1 693 ? 148.635 119.549 130.186 1.00 84.66  0  692 TYR A CD2 1 
ATOM   5486 C  CE1 . TYR A 1 693 ? 147.471 117.861 128.345 1.00 84.66  0  692 TYR A CE1 1 
ATOM   5487 C  CE2 . TYR A 1 693 ? 148.581 118.192 130.436 1.00 84.66  0  692 TYR A CE2 1 
ATOM   5488 C  CZ  . TYR A 1 693 ? 147.998 117.353 129.512 1.00 84.66  0  692 TYR A CZ  1 
ATOM   5489 O  OH  . TYR A 1 693 ? 147.943 116.000 129.756 1.00 84.66  0  692 TYR A OH  1 
ATOM   5490 N  N   . ASN A 1 694 ? 147.273 123.403 131.373 1.00 84.02  0  693 ASN A N   1 
ATOM   5491 C  CA  . ASN A 1 694 ? 147.167 123.529 132.820 1.00 84.02  0  693 ASN A CA  1 
ATOM   5492 C  C   . ASN A 1 694 ? 146.033 124.448 133.249 1.00 84.02  0  693 ASN A C   1 
ATOM   5493 O  O   . ASN A 1 694 ? 145.323 124.141 134.210 1.00 84.02  0  693 ASN A O   1 
ATOM   5494 C  CB  . ASN A 1 694 ? 148.487 124.041 133.403 1.00 84.02  0  693 ASN A CB  1 
ATOM   5495 C  CG  . ASN A 1 694 ? 149.469 122.925 133.688 1.00 84.02  0  693 ASN A CG  1 
ATOM   5496 O  OD1 . ASN A 1 694 ? 150.405 122.696 132.923 1.00 84.02  0  693 ASN A OD1 1 
ATOM   5497 N  ND2 . ASN A 1 694 ? 149.261 122.221 134.795 1.00 84.02  0  693 ASN A ND2 1 
ATOM   5498 N  N   . HIS A 1 695 ? 145.847 125.569 132.557 1.00 87.57  0  694 HIS A N   1 
ATOM   5499 C  CA  . HIS A 1 695 ? 144.755 126.501 132.836 1.00 87.57  0  694 HIS A CA  1 
ATOM   5500 C  C   . HIS A 1 695 ? 143.844 126.564 131.619 1.00 87.57  0  694 HIS A C   1 
ATOM   5501 O  O   . HIS A 1 695 ? 144.156 127.271 130.644 1.00 87.57  0  694 HIS A O   1 
ATOM   5502 C  CB  . HIS A 1 695 ? 145.290 127.890 133.181 1.00 87.57  0  694 HIS A CB  1 
ATOM   5503 C  CG  . HIS A 1 695 ? 146.085 127.939 134.449 1.00 87.57  0  694 HIS A CG  1 
ATOM   5504 N  ND1 . HIS A 1 695 ? 147.058 127.013 134.757 1.00 87.57  0  694 HIS A ND1 1 
ATOM   5505 C  CD2 . HIS A 1 695 ? 146.052 128.807 135.488 1.00 87.57  0  694 HIS A CD2 1 
ATOM   5506 C  CE1 . HIS A 1 695 ? 147.589 127.307 135.930 1.00 87.57  0  694 HIS A CE1 1 
ATOM   5507 N  NE2 . HIS A 1 695 ? 146.996 128.391 136.395 1.00 87.57  0  694 HIS A NE2 1 
ATOM   5508 N  N   . PRO A 1 696 ? 142.726 125.842 131.617 1.00 90.10  0  695 PRO A N   1 
ATOM   5509 C  CA  . PRO A 1 696 ? 141.855 125.855 130.446 1.00 90.10  0  695 PRO A CA  1 
ATOM   5510 C  C   . PRO A 1 696 ? 141.267 127.233 130.229 1.00 90.10  0  695 PRO A C   1 
ATOM   5511 O  O   . PRO A 1 696 ? 140.995 127.973 131.193 1.00 90.10  0  695 PRO A O   1 
ATOM   5512 C  CB  . PRO A 1 696 ? 140.770 124.828 130.803 1.00 90.10  0  695 PRO A CB  1 
ATOM   5513 C  CG  . PRO A 1 696 ? 141.387 123.969 131.859 1.00 90.10  0  695 PRO A CG  1 
ATOM   5514 C  CD  . PRO A 1 696 ? 142.259 124.896 132.643 1.00 90.10  0  695 PRO A CD  1 
ATOM   5515 N  N   . PRO A 1 697 ? 141.052 127.625 128.972 1.00 94.95  0  696 PRO A N   1 
ATOM   5516 C  CA  . PRO A 1 697 ? 140.445 128.934 128.700 1.00 94.95  0  696 PRO A CA  1 
ATOM   5517 C  C   . PRO A 1 697 ? 138.926 128.892 128.707 1.00 94.95  0  696 PRO A C   1 
ATOM   5518 O  O   . PRO A 1 697 ? 138.271 129.925 128.876 1.00 94.95  0  696 PRO A O   1 
ATOM   5519 C  CB  . PRO A 1 697 ? 140.987 129.291 127.311 1.00 94.95  0  696 PRO A CB  1 
ATOM   5520 C  CG  . PRO A 1 697 ? 141.426 127.986 126.694 1.00 94.95  0  696 PRO A CG  1 
ATOM   5521 C  CD  . PRO A 1 697 ? 141.399 126.903 127.737 1.00 94.95  0  696 PRO A CD  1 
ATOM   5522 N  N   . PHE A 1 698 ? 138.356 127.704 128.524 1.00 103.28 0  697 PHE A N   1 
ATOM   5523 C  CA  . PHE A 1 698 ? 136.915 127.525 128.460 1.00 103.28 0  697 PHE A CA  1 
ATOM   5524 C  C   . PHE A 1 698 ? 136.457 126.586 129.568 1.00 103.28 0  697 PHE A C   1 
ATOM   5525 O  O   . PHE A 1 698 ? 137.194 125.690 129.990 1.00 103.28 0  697 PHE A O   1 
ATOM   5526 C  CB  . PHE A 1 698 ? 136.484 126.981 127.094 1.00 103.28 0  697 PHE A CB  1 
ATOM   5527 C  CG  . PHE A 1 698 ? 136.528 128.003 125.995 1.00 103.28 0  697 PHE A CG  1 
ATOM   5528 C  CD1 . PHE A 1 698 ? 137.716 128.289 125.344 1.00 103.28 0  697 PHE A CD1 1 
ATOM   5529 C  CD2 . PHE A 1 698 ? 135.381 128.679 125.613 1.00 103.28 0  697 PHE A CD2 1 
ATOM   5530 C  CE1 . PHE A 1 698 ? 137.760 129.229 124.333 1.00 103.28 0  697 PHE A CE1 1 
ATOM   5531 C  CE2 . PHE A 1 698 ? 135.418 129.620 124.603 1.00 103.28 0  697 PHE A CE2 1 
ATOM   5532 C  CZ  . PHE A 1 698 ? 136.609 129.896 123.962 1.00 103.28 0  697 PHE A CZ  1 
ATOM   5533 N  N   . ARG A 1 699 ? 135.228 126.811 130.038 1.00 104.01 0  698 ARG A N   1 
ATOM   5534 C  CA  . ARG A 1 699 ? 134.715 126.058 131.179 1.00 104.01 0  698 ARG A CA  1 
ATOM   5535 C  C   . ARG A 1 699 ? 134.537 124.582 130.846 1.00 104.01 0  698 ARG A C   1 
ATOM   5536 O  O   . ARG A 1 699 ? 134.779 123.715 131.694 1.00 104.01 0  698 ARG A O   1 
ATOM   5537 C  CB  . ARG A 1 699 ? 133.391 126.662 131.648 1.00 104.01 0  698 ARG A CB  1 
ATOM   5538 C  CG  . ARG A 1 699 ? 133.492 128.102 132.133 1.00 104.01 0  698 ARG A CG  1 
ATOM   5539 C  CD  . ARG A 1 699 ? 134.160 128.196 133.496 1.00 104.01 0  698 ARG A CD  1 
ATOM   5540 N  NE  . ARG A 1 699 ? 135.604 128.369 133.389 1.00 104.01 0  698 ARG A NE  1 
ATOM   5541 C  CZ  . ARG A 1 699 ? 136.455 128.208 134.393 1.00 104.01 0  698 ARG A CZ  1 
ATOM   5542 N  NH1 . ARG A 1 699 ? 136.040 127.869 135.603 1.00 104.01 1  698 ARG A NH1 1 
ATOM   5543 N  NH2 . ARG A 1 699 ? 137.754 128.394 134.179 1.00 104.01 0  698 ARG A NH2 1 
ATOM   5544 N  N   . ASP A 1 700 ? 134.103 124.276 129.620 1.00 106.45 0  699 ASP A N   1 
ATOM   5545 C  CA  . ASP A 1 700 ? 133.762 122.898 129.272 1.00 106.45 0  699 ASP A CA  1 
ATOM   5546 C  C   . ASP A 1 700 ? 134.981 121.984 129.345 1.00 106.45 0  699 ASP A C   1 
ATOM   5547 O  O   . ASP A 1 700 ? 134.898 120.862 129.856 1.00 106.45 0  699 ASP A O   1 
ATOM   5548 C  CB  . ASP A 1 700 ? 133.129 122.850 127.881 1.00 106.45 0  699 ASP A CB  1 
ATOM   5549 C  CG  . ASP A 1 700 ? 133.971 123.547 126.831 1.00 106.45 0  699 ASP A CG  1 
ATOM   5550 O  OD1 . ASP A 1 700 ? 134.998 124.155 127.196 1.00 106.45 0  699 ASP A OD1 1 
ATOM   5551 O  OD2 . ASP A 1 700 ? 133.601 123.489 125.639 1.00 106.45 -1 699 ASP A OD2 1 
ATOM   5552 N  N   . MET A 1 701 ? 136.122 122.445 128.840 1.00 105.38 0  700 MET A N   1 
ATOM   5553 C  CA  . MET A 1 701 ? 137.327 121.627 128.846 1.00 105.38 0  700 MET A CA  1 
ATOM   5554 C  C   . MET A 1 701 ? 137.976 121.647 130.223 1.00 105.38 0  700 MET A C   1 
ATOM   5555 O  O   . MET A 1 701 ? 138.136 122.706 130.836 1.00 105.38 0  700 MET A O   1 
ATOM   5556 C  CB  . MET A 1 701 ? 138.318 122.116 127.789 1.00 105.38 0  700 MET A CB  1 
ATOM   5557 C  CG  . MET A 1 701 ? 139.581 121.271 127.700 1.00 105.38 0  700 MET A CG  1 
ATOM   5558 S  SD  . MET A 1 701 ? 140.735 121.835 126.435 1.00 105.38 0  700 MET A SD  1 
ATOM   5559 C  CE  . MET A 1 701 ? 141.351 123.338 127.185 1.00 105.38 0  700 MET A CE  1 
ATOM   5560 N  N   . LYS A 1 702 ? 138.350 120.467 130.705 1.00 101.50 0  701 LYS A N   1 
ATOM   5561 C  CA  . LYS A 1 702 ? 138.937 120.308 132.026 1.00 101.50 0  701 LYS A CA  1 
ATOM   5562 C  C   . LYS A 1 702 ? 140.458 120.398 131.956 1.00 101.50 0  701 LYS A C   1 
ATOM   5563 O  O   . LYS A 1 702 ? 141.057 120.507 130.884 1.00 101.50 0  701 LYS A O   1 
ATOM   5564 C  CB  . LYS A 1 702 ? 138.510 118.975 132.647 1.00 101.50 0  701 LYS A CB  1 
ATOM   5565 C  CG  . LYS A 1 702 ? 139.018 117.753 131.901 1.00 101.50 0  701 LYS A CG  1 
ATOM   5566 C  CD  . LYS A 1 702 ? 138.547 116.468 132.562 1.00 101.50 0  701 LYS A CD  1 
ATOM   5567 C  CE  . LYS A 1 702 ? 137.067 116.231 132.313 1.00 101.50 0  701 LYS A CE  1 
ATOM   5568 N  NZ  . LYS A 1 702 ? 136.780 115.983 130.873 1.00 101.50 1  701 LYS A NZ  1 
ATOM   5569 N  N   . LYS A 1 703 ? 141.070 120.324 133.142 1.00 97.38  0  702 LYS A N   1 
ATOM   5570 C  CA  . LYS A 1 703 ? 142.544 120.471 133.242 1.00 97.38  0  702 LYS A CA  1 
ATOM   5571 C  C   . LYS A 1 703 ? 143.260 119.220 132.744 1.00 97.38  0  702 LYS A C   1 
ATOM   5572 O  O   . LYS A 1 703 ? 142.943 118.120 133.234 1.00 97.38  0  702 LYS A O   1 
ATOM   5573 C  CB  . LYS A 1 703 ? 142.946 120.753 134.693 1.00 97.38  0  702 LYS A CB  1 
ATOM   5574 C  CG  . LYS A 1 703 ? 144.417 121.081 134.909 1.00 97.38  0  702 LYS A CG  1 
ATOM   5575 C  CD  . LYS A 1 703 ? 144.667 121.875 136.173 1.00 97.38  0  702 LYS A CD  1 
ATOM   5576 C  CE  . LYS A 1 703 ? 143.453 122.656 136.630 1.00 97.38  0  702 LYS A CE  1 
ATOM   5577 N  NZ  . LYS A 1 703 ? 143.218 123.853 135.789 1.00 97.38  1  702 LYS A NZ  1 
ATOM   5578 N  N   . GLY A 1 704 ? 144.187 119.394 131.808 1.00 97.61  0  703 GLY A N   1 
ATOM   5579 C  CA  . GLY A 1 704 ? 145.001 118.315 131.304 1.00 97.61  0  703 GLY A CA  1 
ATOM   5580 C  C   . GLY A 1 704 ? 144.604 117.717 129.965 1.00 97.61  0  703 GLY A C   1 
ATOM   5581 O  O   . GLY A 1 704 ? 144.855 116.524 129.750 1.00 97.61  0  703 GLY A O   1 
ATOM   5582 N  N   . MET A 1 705 ? 144.004 118.492 129.065 1.00 101.58 0  704 MET A N   1 
ATOM   5583 C  CA  . MET A 1 705 ? 143.658 118.003 127.738 1.00 101.58 0  704 MET A CA  1 
ATOM   5584 C  C   . MET A 1 705 ? 144.054 119.054 126.712 1.00 101.58 0  704 MET A C   1 
ATOM   5585 O  O   . MET A 1 705 ? 143.852 120.252 126.937 1.00 101.58 0  704 MET A O   1 
ATOM   5586 C  CB  . MET A 1 705 ? 142.165 117.672 127.641 1.00 101.58 0  704 MET A CB  1 
ATOM   5587 C  CG  . MET A 1 705 ? 141.744 117.072 126.311 1.00 101.58 0  704 MET A CG  1 
ATOM   5588 S  SD  . MET A 1 705 ? 140.001 116.614 126.286 1.00 101.58 0  704 MET A SD  1 
ATOM   5589 C  CE  . MET A 1 705 ? 139.827 116.054 124.595 1.00 101.58 0  704 MET A CE  1 
ATOM   5590 N  N   . GLY A 1 706 ? 144.613 118.604 125.586 1.00 102.87 0  705 GLY A N   1 
ATOM   5591 C  CA  . GLY A 1 706 ? 145.230 119.484 124.621 1.00 102.87 0  705 GLY A CA  1 
ATOM   5592 C  C   . GLY A 1 706 ? 144.241 120.119 123.651 1.00 102.87 0  705 GLY A C   1 
ATOM   5593 O  O   . GLY A 1 706 ? 143.027 120.096 123.835 1.00 102.87 0  705 GLY A O   1 
ATOM   5594 N  N   . CYS A 1 707 ? 144.805 120.699 122.588 1.00 105.08 0  706 CYS A N   1 
ATOM   5595 C  CA  . CYS A 1 707 ? 144.017 121.431 121.603 1.00 105.08 0  706 CYS A CA  1 
ATOM   5596 C  C   . CYS A 1 707 ? 143.216 120.524 120.678 1.00 105.08 0  706 CYS A C   1 
ATOM   5597 O  O   . CYS A 1 707 ? 142.632 121.023 119.709 1.00 105.08 0  706 CYS A O   1 
ATOM   5598 C  CB  . CYS A 1 707 ? 144.925 122.340 120.769 1.00 105.08 0  706 CYS A CB  1 
ATOM   5599 S  SG  . CYS A 1 707 ? 145.380 123.894 121.579 1.00 105.08 0  706 CYS A SG  1 
ATOM   5600 N  N   . ASN A 1 708 ? 143.180 119.214 120.936 1.00 103.80 0  707 ASN A N   1 
ATOM   5601 C  CA  . ASN A 1 708 ? 142.319 118.337 120.149 1.00 103.80 0  707 ASN A CA  1 
ATOM   5602 C  C   . ASN A 1 708 ? 140.854 118.717 120.322 1.00 103.80 0  707 ASN A C   1 
ATOM   5603 O  O   . ASN A 1 708 ? 140.076 118.688 119.361 1.00 103.80 0  707 ASN A O   1 
ATOM   5604 C  CB  . ASN A 1 708 ? 142.551 116.879 120.544 1.00 103.80 0  707 ASN A CB  1 
ATOM   5605 C  CG  . ASN A 1 708 ? 143.614 116.210 119.697 1.00 103.80 0  707 ASN A CG  1 
ATOM   5606 O  OD1 . ASN A 1 708 ? 144.189 116.827 118.801 1.00 103.80 0  707 ASN A OD1 1 
ATOM   5607 N  ND2 . ASN A 1 708 ? 143.880 114.939 119.977 1.00 103.80 0  707 ASN A ND2 1 
ATOM   5608 N  N   . GLU A 1 709 ? 140.461 119.077 121.543 1.00 106.70 0  708 GLU A N   1 
ATOM   5609 C  CA  . GLU A 1 709 ? 139.124 119.585 121.817 1.00 106.70 0  708 GLU A CA  1 
ATOM   5610 C  C   . GLU A 1 709 ? 139.257 120.920 122.541 1.00 106.70 0  708 GLU A C   1 
ATOM   5611 O  O   . GLU A 1 709 ? 138.676 121.124 123.612 1.00 106.70 0  708 GLU A O   1 
ATOM   5612 C  CB  . GLU A 1 709 ? 138.310 118.577 122.632 1.00 106.70 0  708 GLU A CB  1 
ATOM   5613 C  CG  . GLU A 1 709 ? 136.821 118.896 122.739 1.00 106.70 0  708 GLU A CG  1 
ATOM   5614 C  CD  . GLU A 1 709 ? 136.043 117.816 123.464 1.00 106.70 0  708 GLU A CD  1 
ATOM   5615 O  OE1 . GLU A 1 709 ? 136.658 116.805 123.865 1.00 106.70 0  708 GLU A OE1 1 
ATOM   5616 O  OE2 . GLU A 1 709 ? 134.816 117.977 123.634 1.00 106.70 -1 708 GLU A OE2 1 
ATOM   5617 N  N   . CYS A 1 710 ? 140.068 121.819 121.977 1.00 107.63 0  709 CYS A N   1 
ATOM   5618 C  CA  . CYS A 1 710 ? 140.325 123.110 122.611 1.00 107.63 0  709 CYS A CA  1 
ATOM   5619 C  C   . CYS A 1 710 ? 139.039 123.911 122.780 1.00 107.63 0  709 CYS A C   1 
ATOM   5620 O  O   . CYS A 1 710 ? 138.953 124.791 123.645 1.00 107.63 0  709 CYS A O   1 
ATOM   5621 C  CB  . CYS A 1 710 ? 141.348 123.895 121.788 1.00 107.63 0  709 CYS A CB  1 
ATOM   5622 S  SG  . CYS A 1 710 ? 141.973 125.406 122.562 1.00 107.63 0  709 CYS A SG  1 
ATOM   5623 N  N   . THR A 1 711 ? 138.024 123.614 121.962 1.00 108.92 0  710 THR A N   1 
ATOM   5624 C  CA  . THR A 1 711 ? 136.730 124.303 121.999 1.00 108.92 0  710 THR A CA  1 
ATOM   5625 C  C   . THR A 1 711 ? 136.900 125.815 121.860 1.00 108.92 0  710 THR A C   1 
ATOM   5626 O  O   . THR A 1 711 ? 136.330 126.591 122.628 1.00 108.92 0  710 THR A O   1 
ATOM   5627 C  CB  . THR A 1 711 ? 135.939 123.964 123.267 1.00 108.92 0  710 THR A CB  1 
ATOM   5628 O  OG1 . THR A 1 711 ? 136.623 124.473 124.419 1.00 108.92 0  710 THR A OG1 1 
ATOM   5629 C  CG2 . THR A 1 711 ? 135.769 122.458 123.404 1.00 108.92 0  710 THR A CG2 1 
ATOM   5630 N  N   . HIS A 1 712 ? 137.693 126.234 120.878 1.00 109.92 0  711 HIS A N   1 
ATOM   5631 C  CA  . HIS A 1 712 ? 137.998 127.634 120.666 1.00 109.92 0  711 HIS A CA  1 
ATOM   5632 C  C   . HIS A 1 712 ? 137.737 127.998 119.210 1.00 109.92 0  711 HIS A C   1 
ATOM   5633 O  O   . HIS A 1 712 ? 138.257 127.325 118.308 1.00 109.92 0  711 HIS A O   1 
ATOM   5634 C  CB  . HIS A 1 712 ? 139.465 127.926 121.033 1.00 109.92 0  711 HIS A CB  1 
ATOM   5635 C  CG  . HIS A 1 712 ? 139.788 129.384 121.136 1.00 109.92 0  711 HIS A CG  1 
ATOM   5636 N  ND1 . HIS A 1 712 ? 138.848 130.333 121.473 1.00 109.92 0  711 HIS A ND1 1 
ATOM   5637 C  CD2 . HIS A 1 712 ? 140.952 130.053 120.961 1.00 109.92 0  711 HIS A CD2 1 
ATOM   5638 C  CE1 . HIS A 1 712 ? 139.416 131.525 121.495 1.00 109.92 0  711 HIS A CE1 1 
ATOM   5639 N  NE2 . HIS A 1 712 ? 140.693 131.383 121.187 1.00 109.92 0  711 HIS A NE2 1 
ATOM   5640 N  N   . PRO A 1 713 ? 136.923 129.021 118.935 1.00 112.47 0  712 PRO A N   1 
ATOM   5641 C  CA  . PRO A 1 713 ? 136.709 129.434 117.535 1.00 112.47 0  712 PRO A CA  1 
ATOM   5642 C  C   . PRO A 1 713 ? 137.987 129.840 116.815 1.00 112.47 0  712 PRO A C   1 
ATOM   5643 O  O   . PRO A 1 713 ? 138.125 129.576 115.614 1.00 112.47 0  712 PRO A O   1 
ATOM   5644 C  CB  . PRO A 1 713 ? 135.724 130.607 117.664 1.00 112.47 0  712 PRO A CB  1 
ATOM   5645 C  CG  . PRO A 1 713 ? 135.803 131.036 119.102 1.00 112.47 0  712 PRO A CG  1 
ATOM   5646 C  CD  . PRO A 1 713 ? 136.091 129.792 119.872 1.00 112.47 0  712 PRO A CD  1 
ATOM   5647 N  N   . SER A 1 714 ? 138.917 130.479 117.510 1.00 110.30 0  713 SER A N   1 
ATOM   5648 C  CA  . SER A 1 714 ? 140.238 130.788 116.979 1.00 110.30 0  713 SER A CA  1 
ATOM   5649 C  C   . SER A 1 714 ? 141.176 129.623 117.320 1.00 110.30 0  713 SER A C   1 
ATOM   5650 O  O   . SER A 1 714 ? 140.664 128.558 117.678 1.00 110.30 0  713 SER A O   1 
ATOM   5651 C  CB  . SER A 1 714 ? 140.685 132.164 117.478 1.00 110.30 0  713 SER A CB  1 
ATOM   5652 O  OG  . SER A 1 714 ? 140.720 132.218 118.891 1.00 110.30 0  713 SER A OG  1 
ATOM   5653 N  N   . CYS A 1 715 ? 142.500 129.761 117.210 1.00 105.86 0  714 CYS A N   1 
ATOM   5654 C  CA  . CYS A 1 715 ? 143.427 128.642 117.406 1.00 105.86 0  714 CYS A CA  1 
ATOM   5655 C  C   . CYS A 1 715 ? 143.169 127.543 116.377 1.00 105.86 0  714 CYS A C   1 
ATOM   5656 O  O   . CYS A 1 715 ? 142.709 126.447 116.703 1.00 105.86 0  714 CYS A O   1 
ATOM   5657 C  CB  . CYS A 1 715 ? 143.351 128.093 118.835 1.00 105.86 0  714 CYS A CB  1 
ATOM   5658 S  SG  . CYS A 1 715 ? 144.753 127.065 119.340 1.00 105.86 0  714 CYS A SG  1 
ATOM   5659 N  N   . GLN A 1 716 ? 143.456 127.865 115.112 1.00 104.87 0  715 GLN A N   1 
ATOM   5660 C  CA  . GLN A 1 716 ? 143.216 127.014 113.950 1.00 104.87 0  715 GLN A CA  1 
ATOM   5661 C  C   . GLN A 1 716 ? 143.602 125.556 114.169 1.00 104.87 0  715 GLN A C   1 
ATOM   5662 O  O   . GLN A 1 716 ? 142.970 124.655 113.609 1.00 104.87 0  715 GLN A O   1 
ATOM   5663 C  CB  . GLN A 1 716 ? 143.978 127.563 112.740 1.00 104.87 0  715 GLN A CB  1 
ATOM   5664 C  CG  . GLN A 1 716 ? 143.553 128.958 112.311 1.00 104.87 0  715 GLN A CG  1 
ATOM   5665 C  CD  . GLN A 1 716 ? 144.466 129.541 111.249 1.00 104.87 0  715 GLN A CD  1 
ATOM   5666 O  OE1 . GLN A 1 716 ? 145.629 129.153 111.133 1.00 104.87 0  715 GLN A OE1 1 
ATOM   5667 N  NE2 . GLN A 1 716 ? 143.943 130.479 110.468 1.00 104.87 0  715 GLN A NE2 1 
ATOM   5668 N  N   . HIS A 1 717 ? 144.648 125.315 114.962 1.00 101.82 0  716 HIS A N   1 
ATOM   5669 C  CA  . HIS A 1 717 ? 145.123 123.963 115.237 1.00 101.82 0  716 HIS A CA  1 
ATOM   5670 C  C   . HIS A 1 717 ? 144.012 123.079 115.792 1.00 101.82 0  716 HIS A C   1 
ATOM   5671 O  O   . HIS A 1 717 ? 143.989 121.870 115.538 1.00 101.82 0  716 HIS A O   1 
ATOM   5672 C  CB  . HIS A 1 717 ? 146.300 123.998 116.213 1.00 101.82 0  716 HIS A CB  1 
ATOM   5673 C  CG  . HIS A 1 717 ? 147.230 125.151 115.997 1.00 101.82 0  716 HIS A CG  1 
ATOM   5674 N  ND1 . HIS A 1 717 ? 147.265 126.245 116.834 1.00 101.82 0  716 HIS A ND1 1 
ATOM   5675 C  CD2 . HIS A 1 717 ? 148.162 125.378 115.041 1.00 101.82 0  716 HIS A CD2 1 
ATOM   5676 C  CE1 . HIS A 1 717 ? 148.177 127.098 116.402 1.00 101.82 0  716 HIS A CE1 1 
ATOM   5677 N  NE2 . HIS A 1 717 ? 148.735 126.596 115.315 1.00 101.82 0  716 HIS A NE2 1 
ATOM   5678 N  N   . SER A 1 718 ? 143.092 123.668 116.550 1.00 104.73 0  717 SER A N   1 
ATOM   5679 C  CA  . SER A 1 718 ? 141.959 122.926 117.093 1.00 104.73 0  717 SER A CA  1 
ATOM   5680 C  C   . SER A 1 718 ? 141.038 122.445 115.976 1.00 104.73 0  717 SER A C   1 
ATOM   5681 O  O   . SER A 1 718 ? 139.828 122.321 116.166 1.00 104.73 0  717 SER A O   1 
ATOM   5682 C  CB  . SER A 1 718 ? 141.175 123.788 118.085 1.00 104.73 0  717 SER A CB  1 
ATOM   5683 O  OG  . SER A 1 718 ? 140.587 124.904 117.440 1.00 104.73 0  717 SER A OG  1 
ATOM   5684 N  N   . MET B 2 1   ? 117.657 152.102 82.814  1.00 101.27 0  1   MET B N   1 
ATOM   5685 C  CA  . MET B 2 1   ? 117.049 151.510 83.999  1.00 101.27 0  1   MET B CA  1 
ATOM   5686 C  C   . MET B 2 1   ? 118.118 151.085 85.001  1.00 101.27 0  1   MET B C   1 
ATOM   5687 O  O   . MET B 2 1   ? 118.457 151.835 85.914  1.00 101.27 0  1   MET B O   1 
ATOM   5688 C  CB  . MET B 2 1   ? 116.174 150.317 83.612  1.00 101.27 0  1   MET B CB  1 
ATOM   5689 C  CG  . MET B 2 1   ? 114.733 150.686 83.301  1.00 101.27 0  1   MET B CG  1 
ATOM   5690 S  SD  . MET B 2 1   ? 114.499 151.208 81.591  1.00 101.27 0  1   MET B SD  1 
ATOM   5691 C  CE  . MET B 2 1   ? 114.421 149.623 80.760  1.00 101.27 0  1   MET B CE  1 
ATOM   5692 N  N   . ALA B 2 2   ? 118.645 149.871 84.828  1.00 101.46 0  2   ALA B N   1 
ATOM   5693 C  CA  . ALA B 2 2   ? 119.718 149.405 85.699  1.00 101.46 0  2   ALA B CA  1 
ATOM   5694 C  C   . ALA B 2 2   ? 120.971 150.257 85.536  1.00 101.46 0  2   ALA B C   1 
ATOM   5695 O  O   . ALA B 2 2   ? 121.642 150.586 86.522  1.00 101.46 0  2   ALA B O   1 
ATOM   5696 C  CB  . ALA B 2 2   ? 120.025 147.935 85.415  1.00 101.46 0  2   ALA B CB  1 
ATOM   5697 N  N   . GLN B 2 3   ? 121.304 150.623 84.296  1.00 101.64 0  3   GLN B N   1 
ATOM   5698 C  CA  . GLN B 2 3   ? 122.502 151.423 84.055  1.00 101.64 0  3   GLN B CA  1 
ATOM   5699 C  C   . GLN B 2 3   ? 122.372 152.819 84.655  1.00 101.64 0  3   GLN B C   1 
ATOM   5700 O  O   . GLN B 2 3   ? 123.318 153.324 85.272  1.00 101.64 0  3   GLN B O   1 
ATOM   5701 C  CB  . GLN B 2 3   ? 122.787 151.503 82.555  1.00 101.64 0  3   GLN B CB  1 
ATOM   5702 C  CG  . GLN B 2 3   ? 123.358 150.223 81.957  1.00 101.64 0  3   GLN B CG  1 
ATOM   5703 C  CD  . GLN B 2 3   ? 122.336 149.106 81.869  1.00 101.64 0  3   GLN B CD  1 
ATOM   5704 O  OE1 . GLN B 2 3   ? 122.506 148.046 82.472  1.00 101.64 0  3   GLN B OE1 1 
ATOM   5705 N  NE2 . GLN B 2 3   ? 121.267 149.339 81.118  1.00 101.64 0  3   GLN B NE2 1 
ATOM   5706 N  N   . VAL B 2 4   ? 121.212 153.459 84.491  1.00 99.62  0  4   VAL B N   1 
ATOM   5707 C  CA  . VAL B 2 4   ? 121.036 154.786 85.075  1.00 99.62  0  4   VAL B CA  1 
ATOM   5708 C  C   . VAL B 2 4   ? 120.955 154.696 86.594  1.00 99.62  0  4   VAL B C   1 
ATOM   5709 O  O   . VAL B 2 4   ? 121.386 155.616 87.300  1.00 99.62  0  4   VAL B O   1 
ATOM   5710 C  CB  . VAL B 2 4   ? 119.808 155.495 84.470  1.00 99.62  0  4   VAL B CB  1 
ATOM   5711 C  CG1 . VAL B 2 4   ? 119.954 155.608 82.959  1.00 99.62  0  4   VAL B CG1 1 
ATOM   5712 C  CG2 . VAL B 2 4   ? 118.522 154.776 84.833  1.00 99.62  0  4   VAL B CG2 1 
ATOM   5713 N  N   . ALA B 2 5   ? 120.420 153.593 87.127  1.00 97.56  0  5   ALA B N   1 
ATOM   5714 C  CA  . ALA B 2 5   ? 120.444 153.388 88.571  1.00 97.56  0  5   ALA B CA  1 
ATOM   5715 C  C   . ALA B 2 5   ? 121.874 153.277 89.084  1.00 97.56  0  5   ALA B C   1 
ATOM   5716 O  O   . ALA B 2 5   ? 122.217 153.855 90.121  1.00 97.56  0  5   ALA B O   1 
ATOM   5717 C  CB  . ALA B 2 5   ? 119.640 152.142 88.940  1.00 97.56  0  5   ALA B CB  1 
ATOM   5718 N  N   . GLY B 2 6   ? 122.725 152.544 88.365  1.00 94.34  0  6   GLY B N   1 
ATOM   5719 C  CA  . GLY B 2 6   ? 124.126 152.465 88.750  1.00 94.34  0  6   GLY B CA  1 
ATOM   5720 C  C   . GLY B 2 6   ? 124.840 153.800 88.633  1.00 94.34  0  6   GLY B C   1 
ATOM   5721 O  O   . GLY B 2 6   ? 125.703 154.128 89.453  1.00 94.34  0  6   GLY B O   1 
ATOM   5722 N  N   . ALA B 2 7   ? 124.499 154.582 87.606  1.00 92.96  0  7   ALA B N   1 
ATOM   5723 C  CA  . ALA B 2 7   ? 125.078 155.915 87.469  1.00 92.96  0  7   ALA B CA  1 
ATOM   5724 C  C   . ALA B 2 7   ? 124.678 156.812 88.635  1.00 92.96  0  7   ALA B C   1 
ATOM   5725 O  O   . ALA B 2 7   ? 125.511 157.548 89.178  1.00 92.96  0  7   ALA B O   1 
ATOM   5726 C  CB  . ALA B 2 7   ? 124.653 156.538 86.140  1.00 92.96  0  7   ALA B CB  1 
ATOM   5727 N  N   . ALA B 2 8   ? 123.404 156.764 89.034  1.00 90.89  0  8   ALA B N   1 
ATOM   5728 C  CA  . ALA B 2 8   ? 122.966 157.516 90.205  1.00 90.89  0  8   ALA B CA  1 
ATOM   5729 C  C   . ALA B 2 8   ? 123.645 157.014 91.471  1.00 90.89  0  8   ALA B C   1 
ATOM   5730 O  O   . ALA B 2 8   ? 123.948 157.806 92.369  1.00 90.89  0  8   ALA B O   1 
ATOM   5731 C  CB  . ALA B 2 8   ? 121.446 157.432 90.346  1.00 90.89  0  8   ALA B CB  1 
ATOM   5732 N  N   . LEU B 2 9   ? 123.889 155.706 91.558  1.00 89.58  0  9   LEU B N   1 
ATOM   5733 C  CA  . LEU B 2 9   ? 124.625 155.147 92.688  1.00 89.58  0  9   LEU B CA  1 
ATOM   5734 C  C   . LEU B 2 9   ? 126.030 155.734 92.763  1.00 89.58  0  9   LEU B C   1 
ATOM   5735 O  O   . LEU B 2 9   ? 126.488 156.163 93.830  1.00 89.58  0  9   LEU B O   1 
ATOM   5736 C  CB  . LEU B 2 9   ? 124.687 153.626 92.544  1.00 89.58  0  9   LEU B CB  1 
ATOM   5737 C  CG  . LEU B 2 9   ? 125.352 152.807 93.645  1.00 89.58  0  9   LEU B CG  1 
ATOM   5738 C  CD1 . LEU B 2 9   ? 124.585 152.979 94.937  1.00 89.58  0  9   LEU B CD1 1 
ATOM   5739 C  CD2 . LEU B 2 9   ? 125.443 151.344 93.248  1.00 89.58  0  9   LEU B CD2 1 
ATOM   5740 N  N   . SER B 2 10  ? 126.723 155.767 91.624  1.00 90.27  0  10  SER B N   1 
ATOM   5741 C  CA  . SER B 2 10  ? 128.066 156.339 91.583  1.00 90.27  0  10  SER B CA  1 
ATOM   5742 C  C   . SER B 2 10  ? 128.044 157.821 91.935  1.00 90.27  0  10  SER B C   1 
ATOM   5743 O  O   . SER B 2 10  ? 128.923 158.309 92.654  1.00 90.27  0  10  SER B O   1 
ATOM   5744 C  CB  . SER B 2 10  ? 128.686 156.122 90.203  1.00 90.27  0  10  SER B CB  1 
ATOM   5745 O  OG  . SER B 2 10  ? 127.961 156.816 89.203  1.00 90.27  0  10  SER B OG  1 
ATOM   5746 N  N   . GLN B 2 11  ? 127.044 158.553 91.437  1.00 89.64  0  11  GLN B N   1 
ATOM   5747 C  CA  . GLN B 2 11  ? 126.925 159.967 91.777  1.00 89.64  0  11  GLN B CA  1 
ATOM   5748 C  C   . GLN B 2 11  ? 126.711 160.154 93.275  1.00 89.64  0  11  GLN B C   1 
ATOM   5749 O  O   . GLN B 2 11  ? 127.297 161.055 93.887  1.00 89.64  0  11  GLN B O   1 
ATOM   5750 C  CB  . GLN B 2 11  ? 125.783 160.603 90.983  1.00 89.64  0  11  GLN B CB  1 
ATOM   5751 C  CG  . GLN B 2 11  ? 125.186 161.842 91.629  1.00 89.64  0  11  GLN B CG  1 
ATOM   5752 C  CD  . GLN B 2 11  ? 125.984 163.096 91.331  1.00 89.64  0  11  GLN B CD  1 
ATOM   5753 O  OE1 . GLN B 2 11  ? 126.017 163.570 90.196  1.00 89.64  0  11  GLN B OE1 1 
ATOM   5754 N  NE2 . GLN B 2 11  ? 126.634 163.640 92.353  1.00 89.64  0  11  GLN B NE2 1 
ATOM   5755 N  N   . ALA B 2 12  ? 125.875 159.308 93.882  1.00 84.07  0  12  ALA B N   1 
ATOM   5756 C  CA  . ALA B 2 12  ? 125.692 159.354 95.328  1.00 84.07  0  12  ALA B CA  1 
ATOM   5757 C  C   . ALA B 2 12  ? 126.982 159.019 96.063  1.00 84.07  0  12  ALA B C   1 
ATOM   5758 O  O   . ALA B 2 12  ? 127.197 159.491 97.185  1.00 84.07  0  12  ALA B O   1 
ATOM   5759 C  CB  . ALA B 2 12  ? 124.575 158.399 95.749  1.00 84.07  0  12  ALA B CB  1 
ATOM   5760 N  N   . GLY B 2 13  ? 127.845 158.208 95.457  1.00 83.31  0  13  GLY B N   1 
ATOM   5761 C  CA  . GLY B 2 13  ? 129.171 157.962 96.000  1.00 83.31  0  13  GLY B CA  1 
ATOM   5762 C  C   . GLY B 2 13  ? 129.518 156.510 96.246  1.00 83.31  0  13  GLY B C   1 
ATOM   5763 O  O   . GLY B 2 13  ? 130.627 156.233 96.723  1.00 83.31  0  13  GLY B O   1 
ATOM   5764 N  N   . TRP B 2 14  ? 128.634 155.561 95.949  1.00 82.65  0  14  TRP B N   1 
ATOM   5765 C  CA  . TRP B 2 14  ? 128.931 154.142 96.125  1.00 82.65  0  14  TRP B CA  1 
ATOM   5766 C  C   . TRP B 2 14  ? 129.487 153.616 94.809  1.00 82.65  0  14  TRP B C   1 
ATOM   5767 O  O   . TRP B 2 14  ? 128.750 153.144 93.942  1.00 82.65  0  14  TRP B O   1 
ATOM   5768 C  CB  . TRP B 2 14  ? 127.683 153.382 96.549  1.00 82.65  0  14  TRP B CB  1 
ATOM   5769 C  CG  . TRP B 2 14  ? 127.447 153.354 98.020  1.00 82.65  0  14  TRP B CG  1 
ATOM   5770 C  CD1 . TRP B 2 14  ? 126.832 154.311 98.769  1.00 82.65  0  14  TRP B CD1 1 
ATOM   5771 C  CD2 . TRP B 2 14  ? 127.795 152.300 98.923  1.00 82.65  0  14  TRP B CD2 1 
ATOM   5772 N  NE1 . TRP B 2 14  ? 126.786 153.926 100.085 1.00 82.65  0  14  TRP B NE1 1 
ATOM   5773 C  CE2 . TRP B 2 14  ? 127.370 152.693 100.206 1.00 82.65  0  14  TRP B CE2 1 
ATOM   5774 C  CE3 . TRP B 2 14  ? 128.430 151.065 98.771  1.00 82.65  0  14  TRP B CE3 1 
ATOM   5775 C  CZ2 . TRP B 2 14  ? 127.561 151.897 101.330 1.00 82.65  0  14  TRP B CZ2 1 
ATOM   5776 C  CZ3 . TRP B 2 14  ? 128.618 150.275 99.888  1.00 82.65  0  14  TRP B CZ3 1 
ATOM   5777 C  CH2 . TRP B 2 14  ? 128.184 150.694 101.151 1.00 82.65  0  14  TRP B CH2 1 
ATOM   5778 N  N   . TYR B 2 15  ? 130.805 153.696 94.657  1.00 85.40  0  15  TYR B N   1 
ATOM   5779 C  CA  . TYR B 2 15  ? 131.459 153.227 93.438  1.00 85.40  0  15  TYR B CA  1 
ATOM   5780 C  C   . TYR B 2 15  ? 131.491 151.705 93.453  1.00 85.40  0  15  TYR B C   1 
ATOM   5781 O  O   . TYR B 2 15  ? 132.427 151.092 93.971  1.00 85.40  0  15  TYR B O   1 
ATOM   5782 C  CB  . TYR B 2 15  ? 132.863 153.809 93.322  1.00 85.40  0  15  TYR B CB  1 
ATOM   5783 C  CG  . TYR B 2 15  ? 132.899 155.294 93.033  1.00 85.40  0  15  TYR B CG  1 
ATOM   5784 C  CD1 . TYR B 2 15  ? 131.763 155.969 92.609  1.00 85.40  0  15  TYR B CD1 1 
ATOM   5785 C  CD2 . TYR B 2 15  ? 134.073 156.020 93.182  1.00 85.40  0  15  TYR B CD2 1 
ATOM   5786 C  CE1 . TYR B 2 15  ? 131.796 157.324 92.343  1.00 85.40  0  15  TYR B CE1 1 
ATOM   5787 C  CE2 . TYR B 2 15  ? 134.115 157.374 92.919  1.00 85.40  0  15  TYR B CE2 1 
ATOM   5788 C  CZ  . TYR B 2 15  ? 132.974 158.021 92.500  1.00 85.40  0  15  TYR B CZ  1 
ATOM   5789 O  OH  . TYR B 2 15  ? 133.011 159.371 92.237  1.00 85.40  0  15  TYR B OH  1 
ATOM   5790 N  N   . LEU B 2 16  ? 130.463 151.091 92.879  1.00 88.29  0  16  LEU B N   1 
ATOM   5791 C  CA  . LEU B 2 16  ? 130.341 149.645 92.799  1.00 88.29  0  16  LEU B CA  1 
ATOM   5792 C  C   . LEU B 2 16  ? 130.547 149.189 91.361  1.00 88.29  0  16  LEU B C   1 
ATOM   5793 O  O   . LEU B 2 16  ? 130.394 149.963 90.412  1.00 88.29  0  16  LEU B O   1 
ATOM   5794 C  CB  . LEU B 2 16  ? 128.969 149.182 93.303  1.00 88.29  0  16  LEU B CB  1 
ATOM   5795 C  CG  . LEU B 2 16  ? 128.685 149.279 94.804  1.00 88.29  0  16  LEU B CG  1 
ATOM   5796 C  CD1 . LEU B 2 16  ? 127.350 148.629 95.137  1.00 88.29  0  16  LEU B CD1 1 
ATOM   5797 C  CD2 . LEU B 2 16  ? 129.802 148.655 95.620  1.00 88.29  0  16  LEU B CD2 1 
ATOM   5798 N  N   . SER B 2 17  ? 130.897 147.917 91.208  1.00 92.74  0  17  SER B N   1 
ATOM   5799 C  CA  . SER B 2 17  ? 131.088 147.317 89.898  1.00 92.74  0  17  SER B CA  1 
ATOM   5800 C  C   . SER B 2 17  ? 129.784 146.701 89.412  1.00 92.74  0  17  SER B C   1 
ATOM   5801 O  O   . SER B 2 17  ? 128.964 146.234 90.207  1.00 92.74  0  17  SER B O   1 
ATOM   5802 C  CB  . SER B 2 17  ? 132.183 146.251 89.933  1.00 92.74  0  17  SER B CB  1 
ATOM   5803 O  OG  . SER B 2 17  ? 131.791 145.145 90.728  1.00 92.74  0  17  SER B OG  1 
ATOM   5804 N  N   . ASP B 2 18  ? 129.610 146.694 88.086  1.00 96.15  0  18  ASP B N   1 
ATOM   5805 C  CA  . ASP B 2 18  ? 128.377 146.186 87.491  1.00 96.15  0  18  ASP B CA  1 
ATOM   5806 C  C   . ASP B 2 18  ? 128.066 144.779 87.982  1.00 96.15  0  18  ASP B C   1 
ATOM   5807 O  O   . ASP B 2 18  ? 126.898 144.425 88.179  1.00 96.15  0  18  ASP B O   1 
ATOM   5808 C  CB  . ASP B 2 18  ? 128.482 146.213 85.967  1.00 96.15  0  18  ASP B CB  1 
ATOM   5809 C  CG  . ASP B 2 18  ? 128.820 147.590 85.432  1.00 96.15  0  18  ASP B CG  1 
ATOM   5810 O  OD1 . ASP B 2 18  ? 128.444 148.590 86.079  1.00 96.15  0  18  ASP B OD1 1 
ATOM   5811 O  OD2 . ASP B 2 18  ? 129.463 147.673 84.364  1.00 96.15  -1 18  ASP B OD2 1 
ATOM   5812 N  N   . GLU B 2 19  ? 129.103 143.970 88.207  1.00 96.53  0  19  GLU B N   1 
ATOM   5813 C  CA  . GLU B 2 19  ? 128.903 142.680 88.857  1.00 96.53  0  19  GLU B CA  1 
ATOM   5814 C  C   . GLU B 2 19  ? 128.325 142.859 90.255  1.00 96.53  0  19  GLU B C   1 
ATOM   5815 O  O   . GLU B 2 19  ? 127.451 142.094 90.676  1.00 96.53  0  19  GLU B O   1 
ATOM   5816 C  CB  . GLU B 2 19  ? 130.222 141.910 88.911  1.00 96.53  0  19  GLU B CB  1 
ATOM   5817 C  CG  . GLU B 2 19  ? 130.156 140.615 89.704  1.00 96.53  0  19  GLU B CG  1 
ATOM   5818 C  CD  . GLU B 2 19  ? 131.496 139.911 89.780  1.00 96.53  0  19  GLU B CD  1 
ATOM   5819 O  OE1 . GLU B 2 19  ? 132.476 140.434 89.209  1.00 96.53  0  19  GLU B OE1 1 
ATOM   5820 O  OE2 . GLU B 2 19  ? 131.570 138.836 90.411  1.00 96.53  -1 19  GLU B OE2 1 
ATOM   5821 N  N   . GLY B 2 20  ? 128.797 143.869 90.988  1.00 96.25  0  20  GLY B N   1 
ATOM   5822 C  CA  . GLY B 2 20  ? 128.255 144.122 92.314  1.00 96.25  0  20  GLY B CA  1 
ATOM   5823 C  C   . GLY B 2 20  ? 126.791 144.516 92.288  1.00 96.25  0  20  GLY B C   1 
ATOM   5824 O  O   . GLY B 2 20  ? 125.993 144.033 93.097  1.00 96.25  0  20  GLY B O   1 
ATOM   5825 N  N   . ILE B 2 21  ? 126.416 145.401 91.360  1.00 97.64  0  21  ILE B N   1 
ATOM   5826 C  CA  . ILE B 2 21  ? 125.007 145.769 91.229  1.00 97.64  0  21  ILE B CA  1 
ATOM   5827 C  C   . ILE B 2 21  ? 124.170 144.558 90.837  1.00 97.64  0  21  ILE B C   1 
ATOM   5828 O  O   . ILE B 2 21  ? 123.089 144.330 91.392  1.00 97.64  0  21  ILE B O   1 
ATOM   5829 C  CB  . ILE B 2 21  ? 124.817 146.935 90.236  1.00 97.64  0  21  ILE B CB  1 
ATOM   5830 C  CG1 . ILE B 2 21  ? 125.464 148.228 90.748  1.00 97.64  0  21  ILE B CG1 1 
ATOM   5831 C  CG2 . ILE B 2 21  ? 123.339 147.163 89.952  1.00 97.64  0  21  ILE B CG2 1 
ATOM   5832 C  CD1 . ILE B 2 21  ? 126.893 148.438 90.342  1.00 97.64  0  21  ILE B CD1 1 
ATOM   5833 N  N   . GLU B 2 22  ? 124.656 143.753 89.887  1.00 101.97 0  22  GLU B N   1 
ATOM   5834 C  CA  . GLU B 2 22  ? 123.908 142.570 89.471  1.00 101.97 0  22  GLU B CA  1 
ATOM   5835 C  C   . GLU B 2 22  ? 123.793 141.547 90.595  1.00 101.97 0  22  GLU B C   1 
ATOM   5836 O  O   . GLU B 2 22  ? 122.837 140.765 90.623  1.00 101.97 0  22  GLU B O   1 
ATOM   5837 C  CB  . GLU B 2 22  ? 124.563 141.940 88.242  1.00 101.97 0  22  GLU B CB  1 
ATOM   5838 C  CG  . GLU B 2 22  ? 124.351 142.724 86.956  1.00 101.97 0  22  GLU B CG  1 
ATOM   5839 C  CD  . GLU B 2 22  ? 122.936 143.254 86.821  1.00 101.97 0  22  GLU B CD  1 
ATOM   5840 O  OE1 . GLU B 2 22  ? 122.029 142.457 86.503  1.00 101.97 0  22  GLU B OE1 1 
ATOM   5841 O  OE2 . GLU B 2 22  ? 122.732 144.469 87.031  1.00 101.97 -1 22  GLU B OE2 1 
ATOM   5842 N  N   . ALA B 2 23  ? 124.758 141.524 91.515  1.00 100.18 0  23  ALA B N   1 
ATOM   5843 C  CA  . ALA B 2 23  ? 124.656 140.651 92.677  1.00 100.18 0  23  ALA B CA  1 
ATOM   5844 C  C   . ALA B 2 23  ? 123.687 141.199 93.716  1.00 100.18 0  23  ALA B C   1 
ATOM   5845 O  O   . ALA B 2 23  ? 123.003 140.422 94.391  1.00 100.18 0  23  ALA B O   1 
ATOM   5846 C  CB  . ALA B 2 23  ? 126.034 140.442 93.305  1.00 100.18 0  23  ALA B CB  1 
ATOM   5847 N  N   . CYS B 2 24  ? 123.615 142.519 93.858  1.00 99.28  0  24  CYS B N   1 
ATOM   5848 C  CA  . CYS B 2 24  ? 122.713 143.172 94.803  1.00 99.28  0  24  CYS B CA  1 
ATOM   5849 C  C   . CYS B 2 24  ? 121.527 143.716 94.009  1.00 99.28  0  24  CYS B C   1 
ATOM   5850 O  O   . CYS B 2 24  ? 121.508 144.882 93.613  1.00 99.28  0  24  CYS B O   1 
ATOM   5851 C  CB  . CYS B 2 24  ? 123.433 144.278 95.568  1.00 99.28  0  24  CYS B CB  1 
ATOM   5852 S  SG  . CYS B 2 24  ? 124.846 143.711 96.544  1.00 99.28  0  24  CYS B SG  1 
ATOM   5853 N  N   . THR B 2 25  ? 120.528 142.863 93.787  1.00 102.31 0  25  THR B N   1 
ATOM   5854 C  CA  . THR B 2 25  ? 119.385 143.202 92.951  1.00 102.31 0  25  THR B CA  1 
ATOM   5855 C  C   . THR B 2 25  ? 118.083 142.972 93.706  1.00 102.31 0  25  THR B C   1 
ATOM   5856 O  O   . THR B 2 25  ? 118.059 142.492 94.843  1.00 102.31 0  25  THR B O   1 
ATOM   5857 C  CB  . THR B 2 25  ? 119.372 142.388 91.649  1.00 102.31 0  25  THR B CB  1 
ATOM   5858 O  OG1 . THR B 2 25  ? 119.551 140.997 91.946  1.00 102.31 0  25  THR B OG1 1 
ATOM   5859 C  CG2 . THR B 2 25  ? 120.453 142.860 90.700  1.00 102.31 0  25  THR B CG2 1 
ATOM   5860 N  N   . SER B 2 26  ? 116.991 143.329 93.033  1.00 104.20 0  26  SER B N   1 
ATOM   5861 C  CA  . SER B 2 26  ? 115.625 143.086 93.473  1.00 104.20 0  26  SER B CA  1 
ATOM   5862 C  C   . SER B 2 26  ? 114.914 142.349 92.348  1.00 104.20 0  26  SER B C   1 
ATOM   5863 O  O   . SER B 2 26  ? 115.579 141.807 91.458  1.00 104.20 0  26  SER B O   1 
ATOM   5864 C  CB  . SER B 2 26  ? 114.913 144.394 93.821  1.00 104.20 0  26  SER B CB  1 
ATOM   5865 O  OG  . SER B 2 26  ? 113.653 144.146 94.419  1.00 104.20 0  26  SER B OG  1 
ATOM   5866 N  N   . SER B 2 27  ? 113.580 142.274 92.404  1.00 104.84 0  27  SER B N   1 
ATOM   5867 C  CA  . SER B 2 27  ? 112.784 141.734 91.305  1.00 104.84 0  27  SER B CA  1 
ATOM   5868 C  C   . SER B 2 27  ? 113.321 142.264 89.981  1.00 104.84 0  27  SER B C   1 
ATOM   5869 O  O   . SER B 2 27  ? 113.318 143.480 89.750  1.00 104.84 0  27  SER B O   1 
ATOM   5870 C  CB  . SER B 2 27  ? 111.309 142.101 91.471  1.00 104.84 0  27  SER B CB  1 
ATOM   5871 O  OG  . SER B 2 27  ? 111.079 143.452 91.111  1.00 104.84 0  27  SER B OG  1 
ATOM   5872 N  N   . PRO B 2 28  ? 113.793 141.386 89.088  1.00 106.57 0  28  PRO B N   1 
ATOM   5873 C  CA  . PRO B 2 28  ? 114.610 141.848 87.956  1.00 106.57 0  28  PRO B CA  1 
ATOM   5874 C  C   . PRO B 2 28  ? 113.824 142.587 86.884  1.00 106.57 0  28  PRO B C   1 
ATOM   5875 O  O   . PRO B 2 28  ? 113.927 142.268 85.696  1.00 106.57 0  28  PRO B O   1 
ATOM   5876 C  CB  . PRO B 2 28  ? 115.206 140.546 87.407  1.00 106.57 0  28  PRO B CB  1 
ATOM   5877 C  CG  . PRO B 2 28  ? 114.208 139.501 87.767  1.00 106.57 0  28  PRO B CG  1 
ATOM   5878 C  CD  . PRO B 2 28  ? 113.590 139.927 89.073  1.00 106.57 0  28  PRO B CD  1 
ATOM   5879 N  N   . ASP B 2 29  ? 113.041 143.582 87.299  1.00 106.36 0  29  ASP B N   1 
ATOM   5880 C  CA  . ASP B 2 29  ? 112.403 144.507 86.368  1.00 106.36 0  29  ASP B CA  1 
ATOM   5881 C  C   . ASP B 2 29  ? 112.498 145.963 86.792  1.00 106.36 0  29  ASP B C   1 
ATOM   5882 O  O   . ASP B 2 29  ? 112.289 146.841 85.948  1.00 106.36 0  29  ASP B O   1 
ATOM   5883 C  CB  . ASP B 2 29  ? 110.926 144.144 86.172  1.00 106.36 0  29  ASP B CB  1 
ATOM   5884 C  CG  . ASP B 2 29  ? 110.701 143.242 84.974  1.00 106.36 0  29  ASP B CG  1 
ATOM   5885 O  OD1 . ASP B 2 29  ? 111.667 142.990 84.225  1.00 106.36 0  29  ASP B OD1 1 
ATOM   5886 O  OD2 . ASP B 2 29  ? 109.555 142.785 84.779  1.00 106.36 -1 29  ASP B OD2 1 
ATOM   5887 N  N   . LYS B 2 30  ? 112.813 146.258 88.054  1.00 107.46 0  30  LYS B N   1 
ATOM   5888 C  CA  . LYS B 2 30  ? 112.981 147.625 88.531  1.00 107.46 0  30  LYS B CA  1 
ATOM   5889 C  C   . LYS B 2 30  ? 113.685 147.621 89.882  1.00 107.46 0  30  LYS B C   1 
ATOM   5890 O  O   . LYS B 2 30  ? 113.239 146.950 90.819  1.00 107.46 0  30  LYS B O   1 
ATOM   5891 C  CB  . LYS B 2 30  ? 111.627 148.334 88.631  1.00 107.46 0  30  LYS B CB  1 
ATOM   5892 C  CG  . LYS B 2 30  ? 111.622 149.541 89.553  1.00 107.46 0  30  LYS B CG  1 
ATOM   5893 C  CD  . LYS B 2 30  ? 110.320 150.316 89.439  1.00 107.46 0  30  LYS B CD  1 
ATOM   5894 C  CE  . LYS B 2 30  ? 110.385 151.341 88.319  1.00 107.46 0  30  LYS B CE  1 
ATOM   5895 N  NZ  . LYS B 2 30  ? 109.028 151.800 87.914  1.00 107.46 1  30  LYS B NZ  1 
ATOM   5896 N  N   . VAL B 2 31  ? 114.787 148.360 89.994  1.00 104.50 0  31  VAL B N   1 
ATOM   5897 C  CA  . VAL B 2 31  ? 115.557 148.457 91.228  1.00 104.50 0  31  VAL B CA  1 
ATOM   5898 C  C   . VAL B 2 31  ? 115.741 149.928 91.567  1.00 104.50 0  31  VAL B C   1 
ATOM   5899 O  O   . VAL B 2 31  ? 115.878 150.768 90.670  1.00 104.50 0  31  VAL B O   1 
ATOM   5900 C  CB  . VAL B 2 31  ? 116.923 147.747 91.111  1.00 104.50 0  31  VAL B CB  1 
ATOM   5901 C  CG1 . VAL B 2 31  ? 116.733 146.241 91.028  1.00 104.50 0  31  VAL B CG1 1 
ATOM   5902 C  CG2 . VAL B 2 31  ? 117.689 148.256 89.899  1.00 104.50 0  31  VAL B CG2 1 
ATOM   5903 N  N   . ASN B 2 32  ? 115.733 150.245 92.860  1.00 99.09  0  32  ASN B N   1 
ATOM   5904 C  CA  . ASN B 2 32  ? 115.853 151.622 93.312  1.00 99.09  0  32  ASN B CA  1 
ATOM   5905 C  C   . ASN B 2 32  ? 117.122 151.806 94.137  1.00 99.09  0  32  ASN B C   1 
ATOM   5906 O  O   . ASN B 2 32  ? 117.535 150.920 94.901  1.00 99.09  0  32  ASN B O   1 
ATOM   5907 C  CB  . ASN B 2 32  ? 114.592 152.067 94.094  1.00 99.09  0  32  ASN B CB  1 
ATOM   5908 C  CG  . ASN B 2 32  ? 114.443 151.387 95.449  1.00 99.09  0  32  ASN B CG  1 
ATOM   5909 O  OD1 . ASN B 2 32  ? 115.323 151.459 96.305  1.00 99.09  0  32  ASN B OD1 1 
ATOM   5910 N  ND2 . ASN B 2 32  ? 113.313 150.718 95.644  1.00 99.09  0  32  ASN B ND2 1 
ATOM   5911 N  N   . VAL B 2 33  ? 117.734 152.981 93.965  1.00 96.02  0  33  VAL B N   1 
ATOM   5912 C  CA  . VAL B 2 33  ? 119.030 153.259 94.576  1.00 96.02  0  33  VAL B CA  1 
ATOM   5913 C  C   . VAL B 2 33  ? 118.966 153.074 96.084  1.00 96.02  0  33  VAL B C   1 
ATOM   5914 O  O   . VAL B 2 33  ? 119.947 152.652 96.703  1.00 96.02  0  33  VAL B O   1 
ATOM   5915 C  CB  . VAL B 2 33  ? 119.507 154.675 94.189  1.00 96.02  0  33  VAL B CB  1 
ATOM   5916 C  CG1 . VAL B 2 33  ? 118.512 155.731 94.655  1.00 96.02  0  33  VAL B CG1 1 
ATOM   5917 C  CG2 . VAL B 2 33  ? 120.898 154.949 94.749  1.00 96.02  0  33  VAL B CG2 1 
ATOM   5918 N  N   . ASN B 2 34  ? 117.813 153.354 96.695  1.00 95.81  0  34  ASN B N   1 
ATOM   5919 C  CA  . ASN B 2 34  ? 117.653 153.080 98.119  1.00 95.81  0  34  ASN B CA  1 
ATOM   5920 C  C   . ASN B 2 34  ? 117.790 151.590 98.410  1.00 95.81  0  34  ASN B C   1 
ATOM   5921 O  O   . ASN B 2 34  ? 118.409 151.200 99.407  1.00 95.81  0  34  ASN B O   1 
ATOM   5922 C  CB  . ASN B 2 34  ? 116.303 153.606 98.605  1.00 95.81  0  34  ASN B CB  1 
ATOM   5923 C  CG  . ASN B 2 34  ? 115.984 154.984 98.058  1.00 95.81  0  34  ASN B CG  1 
ATOM   5924 O  OD1 . ASN B 2 34  ? 116.766 155.922 98.214  1.00 95.81  0  34  ASN B OD1 1 
ATOM   5925 N  ND2 . ASN B 2 34  ? 114.831 155.113 97.411  1.00 95.81  0  34  ASN B ND2 1 
ATOM   5926 N  N   . ASP B 2 35  ? 117.219 150.740 97.551  1.00 96.71  0  35  ASP B N   1 
ATOM   5927 C  CA  . ASP B 2 35  ? 117.373 149.300 97.732  1.00 96.71  0  35  ASP B CA  1 
ATOM   5928 C  C   . ASP B 2 35  ? 118.828 148.874 97.582  1.00 96.71  0  35  ASP B C   1 
ATOM   5929 O  O   . ASP B 2 35  ? 119.322 148.052 98.366  1.00 96.71  0  35  ASP B O   1 
ATOM   5930 C  CB  . ASP B 2 35  ? 116.488 148.539 96.745  1.00 96.71  0  35  ASP B CB  1 
ATOM   5931 C  CG  . ASP B 2 35  ? 115.030 148.526 97.160  1.00 96.71  0  35  ASP B CG  1 
ATOM   5932 O  OD1 . ASP B 2 35  ? 114.756 148.605 98.376  1.00 96.71  0  35  ASP B OD1 1 
ATOM   5933 O  OD2 . ASP B 2 35  ? 114.159 148.432 96.271  1.00 96.71  -1 35  ASP B OD2 1 
ATOM   5934 N  N   . ILE B 2 36  ? 119.532 149.411 96.579  1.00 95.31  0  36  ILE B N   1 
ATOM   5935 C  CA  . ILE B 2 36  ? 120.951 149.068 96.448  1.00 95.31  0  36  ILE B CA  1 
ATOM   5936 C  C   . ILE B 2 36  ? 121.736 149.508 97.680  1.00 95.31  0  36  ILE B C   1 
ATOM   5937 O  O   . ILE B 2 36  ? 122.595 148.770 98.174  1.00 95.31  0  36  ILE B O   1 
ATOM   5938 C  CB  . ILE B 2 36  ? 121.572 149.626 95.149  1.00 95.31  0  36  ILE B CB  1 
ATOM   5939 C  CG1 . ILE B 2 36  ? 120.933 149.019 93.892  1.00 95.31  0  36  ILE B CG1 1 
ATOM   5940 C  CG2 . ILE B 2 36  ? 123.073 149.388 95.128  1.00 95.31  0  36  ILE B CG2 1 
ATOM   5941 C  CD1 . ILE B 2 36  ? 119.742 149.724 93.353  1.00 95.31  0  36  ILE B CD1 1 
ATOM   5942 N  N   . ILE B 2 37  ? 121.462 150.709 98.197  1.00 93.12  0  37  ILE B N   1 
ATOM   5943 C  CA  . ILE B 2 37  ? 122.154 151.175 99.401  1.00 93.12  0  37  ILE B CA  1 
ATOM   5944 C  C   . ILE B 2 37  ? 121.876 150.244 100.574 1.00 93.12  0  37  ILE B C   1 
ATOM   5945 O  O   . ILE B 2 37  ? 122.789 149.861 101.318 1.00 93.12  0  37  ILE B O   1 
ATOM   5946 C  CB  . ILE B 2 37  ? 121.754 152.625 99.734  1.00 93.12  0  37  ILE B CB  1 
ATOM   5947 C  CG1 . ILE B 2 37  ? 122.096 153.569 98.585  1.00 93.12  0  37  ILE B CG1 1 
ATOM   5948 C  CG2 . ILE B 2 37  ? 122.429 153.087 101.015 1.00 93.12  0  37  ILE B CG2 1 
ATOM   5949 C  CD1 . ILE B 2 37  ? 123.561 153.619 98.269  1.00 93.12  0  37  ILE B CD1 1 
ATOM   5950 N  N   . LEU B 2 38  ? 120.607 149.877 100.766 1.00 94.87  0  38  LEU B N   1 
ATOM   5951 C  CA  . LEU B 2 38  ? 120.248 149.036 101.902 1.00 94.87  0  38  LEU B CA  1 
ATOM   5952 C  C   . LEU B 2 38  ? 120.917 147.672 101.810 1.00 94.87  0  38  LEU B C   1 
ATOM   5953 O  O   . LEU B 2 38  ? 121.393 147.136 102.818 1.00 94.87  0  38  LEU B O   1 
ATOM   5954 C  CB  . LEU B 2 38  ? 118.730 148.886 101.988 1.00 94.87  0  38  LEU B CB  1 
ATOM   5955 C  CG  . LEU B 2 38  ? 118.199 148.274 103.286 1.00 94.87  0  38  LEU B CG  1 
ATOM   5956 C  CD1 . LEU B 2 38  ? 118.616 149.115 104.484 1.00 94.87  0  38  LEU B CD1 1 
ATOM   5957 C  CD2 . LEU B 2 38  ? 116.687 148.124 103.231 1.00 94.87  0  38  LEU B CD2 1 
ATOM   5958 N  N   . ILE B 2 39  ? 120.963 147.091 100.609 1.00 95.00  0  39  ILE B N   1 
ATOM   5959 C  CA  . ILE B 2 39  ? 121.619 145.797 100.449 1.00 95.00  0  39  ILE B CA  1 
ATOM   5960 C  C   . ILE B 2 39  ? 123.125 145.927 100.654 1.00 95.00  0  39  ILE B C   1 
ATOM   5961 O  O   . ILE B 2 39  ? 123.751 145.079 101.302 1.00 95.00  0  39  ILE B O   1 
ATOM   5962 C  CB  . ILE B 2 39  ? 121.280 145.190 99.076  1.00 95.00  0  39  ILE B CB  1 
ATOM   5963 C  CG1 . ILE B 2 39  ? 119.775 144.945 98.961  1.00 95.00  0  39  ILE B CG1 1 
ATOM   5964 C  CG2 . ILE B 2 39  ? 122.033 143.886 98.874  1.00 95.00  0  39  ILE B CG2 1 
ATOM   5965 C  CD1 . ILE B 2 39  ? 119.316 144.600 97.562  1.00 95.00  0  39  ILE B CD1 1 
ATOM   5966 N  N   . ALA B 2 40  ? 123.730 146.989 100.114 1.00 92.17  0  40  ALA B N   1 
ATOM   5967 C  CA  . ALA B 2 40  ? 125.177 147.155 100.203 1.00 92.17  0  40  ALA B CA  1 
ATOM   5968 C  C   . ALA B 2 40  ? 125.632 147.357 101.642 1.00 92.17  0  40  ALA B C   1 
ATOM   5969 O  O   . ALA B 2 40  ? 126.686 146.847 102.039 1.00 92.17  0  40  ALA B O   1 
ATOM   5970 C  CB  . ALA B 2 40  ? 125.624 148.326 99.329  1.00 92.17  0  40  ALA B CB  1 
ATOM   5971 N  N   . LEU B 2 41  ? 124.863 148.113 102.432 1.00 89.88  0  41  LEU B N   1 
ATOM   5972 C  CA  . LEU B 2 41  ? 125.233 148.331 103.829 1.00 89.88  0  41  LEU B CA  1 
ATOM   5973 C  C   . LEU B 2 41  ? 125.382 147.012 104.578 1.00 89.88  0  41  LEU B C   1 
ATOM   5974 O  O   . LEU B 2 41  ? 126.268 146.869 105.428 1.00 89.88  0  41  LEU B O   1 
ATOM   5975 C  CB  . LEU B 2 41  ? 124.200 149.225 104.516 1.00 89.88  0  41  LEU B CB  1 
ATOM   5976 C  CG  . LEU B 2 41  ? 124.574 150.699 104.691 1.00 89.88  0  41  LEU B CG  1 
ATOM   5977 C  CD1 . LEU B 2 41  ? 124.654 151.411 103.355 1.00 89.88  0  41  LEU B CD1 1 
ATOM   5978 C  CD2 . LEU B 2 41  ? 123.574 151.390 105.606 1.00 89.88  0  41  LEU B CD2 1 
ATOM   5979 N  N   . ASN B 2 42  ? 124.524 146.037 104.278 1.00 93.37  0  42  ASN B N   1 
ATOM   5980 C  CA  . ASN B 2 42  ? 124.624 144.722 104.894 1.00 93.37  0  42  ASN B CA  1 
ATOM   5981 C  C   . ASN B 2 42  ? 125.669 143.831 104.233 1.00 93.37  0  42  ASN B C   1 
ATOM   5982 O  O   . ASN B 2 42  ? 125.949 142.746 104.753 1.00 93.37  0  42  ASN B O   1 
ATOM   5983 C  CB  . ASN B 2 42  ? 123.262 144.023 104.863 1.00 93.37  0  42  ASN B CB  1 
ATOM   5984 C  CG  . ASN B 2 42  ? 122.208 144.766 105.661 1.00 93.37  0  42  ASN B CG  1 
ATOM   5985 O  OD1 . ASN B 2 42  ? 121.207 145.227 105.112 1.00 93.37  0  42  ASN B OD1 1 
ATOM   5986 N  ND2 . ASN B 2 42  ? 122.428 144.887 106.965 1.00 93.37  0  42  ASN B ND2 1 
ATOM   5987 N  N   . THR B 2 43  ? 126.247 144.256 103.114 1.00 90.89  0  43  THR B N   1 
ATOM   5988 C  CA  . THR B 2 43  ? 127.203 143.453 102.366 1.00 90.89  0  43  THR B CA  1 
ATOM   5989 C  C   . THR B 2 43  ? 128.623 143.939 102.628 1.00 90.89  0  43  THR B C   1 
ATOM   5990 O  O   . THR B 2 43  ? 128.875 145.145 102.694 1.00 90.89  0  43  THR B O   1 
ATOM   5991 C  CB  . THR B 2 43  ? 126.901 143.510 100.865 1.00 90.89  0  43  THR B CB  1 
ATOM   5992 O  OG1 . THR B 2 43  ? 125.552 143.087 100.632 1.00 90.89  0  43  THR B OG1 1 
ATOM   5993 C  CG2 . THR B 2 43  ? 127.846 142.603 100.088 1.00 90.89  0  43  THR B CG2 1 
ATOM   5994 N  N   . ASP B 2 44  ? 129.545 142.991 102.787 1.00 88.19  0  44  ASP B N   1 
ATOM   5995 C  CA  . ASP B 2 44  ? 130.950 143.335 102.959 1.00 88.19  0  44  ASP B CA  1 
ATOM   5996 C  C   . ASP B 2 44  ? 131.473 144.050 101.720 1.00 88.19  0  44  ASP B C   1 
ATOM   5997 O  O   . ASP B 2 44  ? 131.092 143.733 100.590 1.00 88.19  0  44  ASP B O   1 
ATOM   5998 C  CB  . ASP B 2 44  ? 131.773 142.075 103.234 1.00 88.19  0  44  ASP B CB  1 
ATOM   5999 C  CG  . ASP B 2 44  ? 133.222 142.382 103.562 1.00 88.19  0  44  ASP B CG  1 
ATOM   6000 O  OD1 . ASP B 2 44  ? 133.978 142.759 102.644 1.00 88.19  0  44  ASP B OD1 1 
ATOM   6001 O  OD2 . ASP B 2 44  ? 133.606 142.241 104.741 1.00 88.19  -1 44  ASP B OD2 1 
ATOM   6002 N  N   . LEU B 2 45  ? 132.356 145.027 101.939 1.00 83.16  0  45  LEU B N   1 
ATOM   6003 C  CA  . LEU B 2 45  ? 132.835 145.846 100.831 1.00 83.16  0  45  LEU B CA  1 
ATOM   6004 C  C   . LEU B 2 45  ? 133.825 145.094 99.949  1.00 83.16  0  45  LEU B C   1 
ATOM   6005 O  O   . LEU B 2 45  ? 134.000 145.452 98.781  1.00 83.16  0  45  LEU B O   1 
ATOM   6006 C  CB  . LEU B 2 45  ? 133.465 147.136 101.362 1.00 83.16  0  45  LEU B CB  1 
ATOM   6007 C  CG  . LEU B 2 45  ? 133.870 148.183 100.319 1.00 83.16  0  45  LEU B CG  1 
ATOM   6008 C  CD1 . LEU B 2 45  ? 132.741 148.415 99.326  1.00 83.16  0  45  LEU B CD1 1 
ATOM   6009 C  CD2 . LEU B 2 45  ? 134.278 149.489 100.980 1.00 83.16  0  45  LEU B CD2 1 
ATOM   6010 N  N   . ARG B 2 46  ? 134.488 144.063 100.478 1.00 80.42  0  46  ARG B N   1 
ATOM   6011 C  CA  . ARG B 2 46  ? 135.460 143.337 99.664  1.00 80.42  0  46  ARG B CA  1 
ATOM   6012 C  C   . ARG B 2 46  ? 134.787 142.479 98.600  1.00 80.42  0  46  ARG B C   1 
ATOM   6013 O  O   . ARG B 2 46  ? 135.357 142.273 97.523  1.00 80.42  0  46  ARG B O   1 
ATOM   6014 C  CB  . ARG B 2 46  ? 136.357 142.471 100.548 1.00 80.42  0  46  ARG B CB  1 
ATOM   6015 C  CG  . ARG B 2 46  ? 137.086 143.234 101.639 1.00 80.42  0  46  ARG B CG  1 
ATOM   6016 C  CD  . ARG B 2 46  ? 138.518 142.745 101.778 1.00 80.42  0  46  ARG B CD  1 
ATOM   6017 N  NE  . ARG B 2 46  ? 138.635 141.642 102.724 1.00 80.42  0  46  ARG B NE  1 
ATOM   6018 C  CZ  . ARG B 2 46  ? 138.660 141.783 104.042 1.00 80.42  0  46  ARG B CZ  1 
ATOM   6019 N  NH1 . ARG B 2 46  ? 138.585 142.975 104.611 1.00 80.42  1  46  ARG B NH1 1 
ATOM   6020 N  NH2 . ARG B 2 46  ? 138.767 140.702 104.809 1.00 80.42  0  46  ARG B NH2 1 
ATOM   6021 N  N   . THR B 2 47  ? 133.586 141.966 98.880  1.00 83.78  0  47  THR B N   1 
ATOM   6022 C  CA  . THR B 2 47  ? 132.913 141.089 97.925  1.00 83.78  0  47  THR B CA  1 
ATOM   6023 C  C   . THR B 2 47  ? 132.527 141.835 96.653  1.00 83.78  0  47  THR B C   1 
ATOM   6024 O  O   . THR B 2 47  ? 132.638 141.289 95.549  1.00 83.78  0  47  THR B O   1 
ATOM   6025 C  CB  . THR B 2 47  ? 131.678 140.461 98.569  1.00 83.78  0  47  THR B CB  1 
ATOM   6026 O  OG1 . THR B 2 47  ? 130.936 141.468 99.268  1.00 83.78  0  47  THR B OG1 1 
ATOM   6027 C  CG2 . THR B 2 47  ? 132.084 139.368 99.547  1.00 83.78  0  47  THR B CG2 1 
ATOM   6028 N  N   . ILE B 2 48  ? 132.073 143.079 96.786  1.00 85.03  0  48  ILE B N   1 
ATOM   6029 C  CA  . ILE B 2 48  ? 131.612 143.867 95.647  1.00 85.03  0  48  ILE B CA  1 
ATOM   6030 C  C   . ILE B 2 48  ? 132.490 145.102 95.506  1.00 85.03  0  48  ILE B C   1 
ATOM   6031 O  O   . ILE B 2 48  ? 133.477 145.261 96.231  1.00 85.03  0  48  ILE B O   1 
ATOM   6032 C  CB  . ILE B 2 48  ? 130.132 144.257 95.801  1.00 85.03  0  48  ILE B CB  1 
ATOM   6033 C  CG1 . ILE B 2 48  ? 129.915 145.014 97.113  1.00 85.03  0  48  ILE B CG1 1 
ATOM   6034 C  CG2 . ILE B 2 48  ? 129.248 143.021 95.743  1.00 85.03  0  48  ILE B CG2 1 
ATOM   6035 C  CD1 . ILE B 2 48  ? 128.507 145.534 97.291  1.00 85.03  0  48  ILE B CD1 1 
ATOM   6036 N  N   . GLY B 2 49  ? 132.166 145.963 94.553  1.00 85.27  0  49  GLY B N   1 
ATOM   6037 C  CA  . GLY B 2 49  ? 132.844 147.237 94.427  1.00 85.27  0  49  GLY B CA  1 
ATOM   6038 C  C   . GLY B 2 49  ? 133.861 147.262 93.307  1.00 85.27  0  49  GLY B C   1 
ATOM   6039 O  O   . GLY B 2 49  ? 133.974 146.346 92.487  1.00 85.27  0  49  GLY B O   1 
ATOM   6040 N  N   . LYS B 2 50  ? 134.634 148.341 93.299  1.00 81.02  0  50  LYS B N   1 
ATOM   6041 C  CA  . LYS B 2 50  ? 135.581 148.618 92.227  1.00 81.02  0  50  LYS B CA  1 
ATOM   6042 C  C   . LYS B 2 50  ? 136.805 149.281 92.849  1.00 81.02  0  50  LYS B C   1 
ATOM   6043 O  O   . LYS B 2 50  ? 136.987 149.252 94.071  1.00 81.02  0  50  LYS B O   1 
ATOM   6044 C  CB  . LYS B 2 50  ? 134.912 149.476 91.138  1.00 81.02  0  50  LYS B CB  1 
ATOM   6045 C  CG  . LYS B 2 50  ? 135.468 149.268 89.737  1.00 81.02  0  50  LYS B CG  1 
ATOM   6046 C  CD  . LYS B 2 50  ? 134.504 149.772 88.673  1.00 81.02  0  50  LYS B CD  1 
ATOM   6047 C  CE  . LYS B 2 50  ? 133.878 151.101 89.067  1.00 81.02  0  50  LYS B CE  1 
ATOM   6048 N  NZ  . LYS B 2 50  ? 133.271 151.796 87.899  1.00 81.02  1  50  LYS B NZ  1 
ATOM   6049 N  N   . LYS B 2 51  ? 137.648 149.879 92.013  1.00 79.74  0  51  LYS B N   1 
ATOM   6050 C  CA  . LYS B 2 51  ? 138.895 150.497 92.456  1.00 79.74  0  51  LYS B CA  1 
ATOM   6051 C  C   . LYS B 2 51  ? 138.876 151.973 92.071  1.00 79.74  0  51  LYS B C   1 
ATOM   6052 O  O   . LYS B 2 51  ? 139.098 152.322 90.907  1.00 79.74  0  51  LYS B O   1 
ATOM   6053 C  CB  . LYS B 2 51  ? 140.101 149.784 91.850  1.00 79.74  0  51  LYS B CB  1 
ATOM   6054 C  CG  . LYS B 2 51  ? 141.437 150.424 92.189  1.00 79.74  0  51  LYS B CG  1 
ATOM   6055 C  CD  . LYS B 2 51  ? 142.524 149.978 91.225  1.00 79.74  0  51  LYS B CD  1 
ATOM   6056 C  CE  . LYS B 2 51  ? 142.807 148.492 91.359  1.00 79.74  0  51  LYS B CE  1 
ATOM   6057 N  NZ  . LYS B 2 51  ? 143.889 148.050 90.437  1.00 79.74  1  51  LYS B NZ  1 
ATOM   6058 N  N   . PHE B 2 52  ? 138.609 152.837 93.048  1.00 79.88  0  52  PHE B N   1 
ATOM   6059 C  CA  . PHE B 2 52  ? 138.748 154.275 92.871  1.00 79.88  0  52  PHE B CA  1 
ATOM   6060 C  C   . PHE B 2 52  ? 139.878 154.876 93.688  1.00 79.88  0  52  PHE B C   1 
ATOM   6061 O  O   . PHE B 2 52  ? 140.430 155.903 93.289  1.00 79.88  0  52  PHE B O   1 
ATOM   6062 C  CB  . PHE B 2 52  ? 137.436 154.995 93.217  1.00 79.88  0  52  PHE B CB  1 
ATOM   6063 C  CG  . PHE B 2 52  ? 136.941 154.735 94.612  1.00 79.88  0  52  PHE B CG  1 
ATOM   6064 C  CD1 . PHE B 2 52  ? 137.421 155.463 95.686  1.00 79.88  0  52  PHE B CD1 1 
ATOM   6065 C  CD2 . PHE B 2 52  ? 135.971 153.775 94.843  1.00 79.88  0  52  PHE B CD2 1 
ATOM   6066 C  CE1 . PHE B 2 52  ? 136.961 155.222 96.964  1.00 79.88  0  52  PHE B CE1 1 
ATOM   6067 C  CE2 . PHE B 2 52  ? 135.498 153.539 96.117  1.00 79.88  0  52  PHE B CE2 1 
ATOM   6068 C  CZ  . PHE B 2 52  ? 135.995 154.261 97.179  1.00 79.88  0  52  PHE B CZ  1 
ATOM   6069 N  N   . LEU B 2 53  ? 140.228 154.270 94.815  1.00 75.08  0  53  LEU B N   1 
ATOM   6070 C  CA  . LEU B 2 53  ? 141.406 154.686 95.556  1.00 75.08  0  53  LEU B CA  1 
ATOM   6071 C  C   . LEU B 2 53  ? 142.646 154.404 94.718  1.00 75.08  0  53  LEU B C   1 
ATOM   6072 O  O   . LEU B 2 53  ? 142.853 153.253 94.303  1.00 75.08  0  53  LEU B O   1 
ATOM   6073 C  CB  . LEU B 2 53  ? 141.492 153.949 96.889  1.00 75.08  0  53  LEU B CB  1 
ATOM   6074 C  CG  . LEU B 2 53  ? 140.704 154.519 98.067  1.00 75.08  0  53  LEU B CG  1 
ATOM   6075 C  CD1 . LEU B 2 53  ? 140.817 153.604 99.275  1.00 75.08  0  53  LEU B CD1 1 
ATOM   6076 C  CD2 . LEU B 2 53  ? 141.196 155.912 98.408  1.00 75.08  0  53  LEU B CD2 1 
ATOM   6077 N  N   . PRO B 2 54  ? 143.481 155.400 94.438  1.00 72.28  0  54  PRO B N   1 
ATOM   6078 C  CA  . PRO B 2 54  ? 144.697 155.138 93.663  1.00 72.28  0  54  PRO B CA  1 
ATOM   6079 C  C   . PRO B 2 54  ? 145.650 154.238 94.429  1.00 72.28  0  54  PRO B C   1 
ATOM   6080 O  O   . PRO B 2 54  ? 145.708 154.259 95.661  1.00 72.28  0  54  PRO B O   1 
ATOM   6081 C  CB  . PRO B 2 54  ? 145.294 156.534 93.453  1.00 72.28  0  54  PRO B CB  1 
ATOM   6082 C  CG  . PRO B 2 54  ? 144.752 157.347 94.576  1.00 72.28  0  54  PRO B CG  1 
ATOM   6083 C  CD  . PRO B 2 54  ? 143.387 156.802 94.876  1.00 72.28  0  54  PRO B CD  1 
ATOM   6084 N  N   . SER B 2 55  ? 146.407 153.434 93.682  1.00 73.22  0  55  SER B N   1 
ATOM   6085 C  CA  . SER B 2 55  ? 147.365 152.536 94.313  1.00 73.22  0  55  SER B CA  1 
ATOM   6086 C  C   . SER B 2 55  ? 148.659 153.277 94.623  1.00 73.22  0  55  SER B C   1 
ATOM   6087 O  O   . SER B 2 55  ? 149.754 152.796 94.312  1.00 73.22  0  55  SER B O   1 
ATOM   6088 C  CB  . SER B 2 55  ? 147.640 151.328 93.415  1.00 73.22  0  55  SER B CB  1 
ATOM   6089 O  OG  . SER B 2 55  ? 148.562 151.655 92.390  1.00 73.22  0  55  SER B OG  1 
ATOM   6090 N  N   . ASP B 2 56  ? 148.535 154.450 95.243  1.00 73.35  0  56  ASP B N   1 
ATOM   6091 C  CA  . ASP B 2 56  ? 149.681 155.221 95.695  1.00 73.35  0  56  ASP B CA  1 
ATOM   6092 C  C   . ASP B 2 56  ? 149.426 155.939 97.012  1.00 73.35  0  56  ASP B C   1 
ATOM   6093 O  O   . ASP B 2 56  ? 150.287 156.711 97.447  1.00 73.35  0  56  ASP B O   1 
ATOM   6094 C  CB  . ASP B 2 56  ? 150.094 156.247 94.627  1.00 73.35  0  56  ASP B CB  1 
ATOM   6095 C  CG  . ASP B 2 56  ? 150.945 155.637 93.530  1.00 73.35  0  56  ASP B CG  1 
ATOM   6096 O  OD1 . ASP B 2 56  ? 151.783 154.765 93.842  1.00 73.35  0  56  ASP B OD1 1 
ATOM   6097 O  OD2 . ASP B 2 56  ? 150.775 156.030 92.357  1.00 73.35  -1 56  ASP B OD2 1 
ATOM   6098 N  N   . ILE B 2 57  ? 148.276 155.719 97.652  1.00 69.86  0  57  ILE B N   1 
ATOM   6099 C  CA  . ILE B 2 57  ? 147.908 156.505 98.826  1.00 69.86  0  57  ILE B CA  1 
ATOM   6100 C  C   . ILE B 2 57  ? 148.841 156.208 99.995  1.00 69.86  0  57  ILE B C   1 
ATOM   6101 O  O   . ILE B 2 57  ? 149.193 157.107 100.768 1.00 69.86  0  57  ILE B O   1 
ATOM   6102 C  CB  . ILE B 2 57  ? 146.426 156.269 99.184  1.00 69.86  0  57  ILE B CB  1 
ATOM   6103 C  CG1 . ILE B 2 57  ? 145.964 157.260 100.255 1.00 69.86  0  57  ILE B CG1 1 
ATOM   6104 C  CG2 . ILE B 2 57  ? 146.171 154.823 99.594  1.00 69.86  0  57  ILE B CG2 1 
ATOM   6105 C  CD1 . ILE B 2 57  ? 144.462 157.314 100.428 1.00 69.86  0  57  ILE B CD1 1 
ATOM   6106 N  N   . ASN B 2 58  ? 149.260 154.949 100.145 1.00 70.68  0  58  ASN B N   1 
ATOM   6107 C  CA  . ASN B 2 58  ? 150.220 154.616 101.191 1.00 70.68  0  58  ASN B CA  1 
ATOM   6108 C  C   . ASN B 2 58  ? 151.637 155.040 100.832 1.00 70.68  0  58  ASN B C   1 
ATOM   6109 O  O   . ASN B 2 58  ? 152.488 155.127 101.724 1.00 70.68  0  58  ASN B O   1 
ATOM   6110 C  CB  . ASN B 2 58  ? 150.184 153.117 101.488 1.00 70.68  0  58  ASN B CB  1 
ATOM   6111 C  CG  . ASN B 2 58  ? 148.815 152.641 101.927 1.00 70.68  0  58  ASN B CG  1 
ATOM   6112 O  OD1 . ASN B 2 58  ? 147.844 153.394 101.891 1.00 70.68  0  58  ASN B OD1 1 
ATOM   6113 N  ND2 . ASN B 2 58  ? 148.731 151.384 102.346 1.00 70.68  0  58  ASN B ND2 1 
ATOM   6114 N  N   . SER B 2 59  ? 151.910 155.302 99.551  1.00 71.67  0  59  SER B N   1 
ATOM   6115 C  CA  . SER B 2 59  ? 153.252 155.708 99.149  1.00 71.67  0  59  SER B CA  1 
ATOM   6116 C  C   . SER B 2 59  ? 153.597 157.102 99.655  1.00 71.67  0  59  SER B C   1 
ATOM   6117 O  O   . SER B 2 59  ? 154.755 157.365 100.001 1.00 71.67  0  59  SER B O   1 
ATOM   6118 C  CB  . SER B 2 59  ? 153.384 155.650 97.627  1.00 71.67  0  59  SER B CB  1 
ATOM   6119 O  OG  . SER B 2 59  ? 152.695 156.725 97.013  1.00 71.67  0  59  SER B OG  1 
ATOM   6120 N  N   . GLY B 2 60  ? 152.620 158.001 99.710  1.00 71.26  0  60  GLY B N   1 
ATOM   6121 C  CA  . GLY B 2 60  ? 152.855 159.364 100.132 1.00 71.26  0  60  GLY B CA  1 
ATOM   6122 C  C   . GLY B 2 60  ? 153.013 160.371 99.017  1.00 71.26  0  60  GLY B C   1 
ATOM   6123 O  O   . GLY B 2 60  ? 153.360 161.524 99.296  1.00 71.26  0  60  GLY B O   1 
ATOM   6124 N  N   . LYS B 2 61  ? 152.771 159.978 97.769  1.00 70.93  0  61  LYS B N   1 
ATOM   6125 C  CA  . LYS B 2 61  ? 152.906 160.872 96.628  1.00 70.93  0  61  LYS B CA  1 
ATOM   6126 C  C   . LYS B 2 61  ? 151.605 161.576 96.268  1.00 70.93  0  61  LYS B C   1 
ATOM   6127 O  O   . LYS B 2 61  ? 151.568 162.304 95.271  1.00 70.93  0  61  LYS B O   1 
ATOM   6128 C  CB  . LYS B 2 61  ? 153.427 160.099 95.413  1.00 70.93  0  61  LYS B CB  1 
ATOM   6129 C  CG  . LYS B 2 61  ? 154.843 159.572 95.576  1.00 70.93  0  61  LYS B CG  1 
ATOM   6130 C  CD  . LYS B 2 61  ? 155.304 158.829 94.333  1.00 70.93  0  61  LYS B CD  1 
ATOM   6131 C  CE  . LYS B 2 61  ? 156.751 158.381 94.462  1.00 70.93  0  61  LYS B CE  1 
ATOM   6132 N  NZ  . LYS B 2 61  ? 156.919 157.345 95.519  1.00 70.93  1  61  LYS B NZ  1 
ATOM   6133 N  N   . VAL B 2 62  ? 150.543 161.379 97.046  1.00 69.72  0  62  VAL B N   1 
ATOM   6134 C  CA  . VAL B 2 62  ? 149.263 162.032 96.812  1.00 69.72  0  62  VAL B CA  1 
ATOM   6135 C  C   . VAL B 2 62  ? 148.864 162.780 98.075  1.00 69.72  0  62  VAL B C   1 
ATOM   6136 O  O   . VAL B 2 62  ? 149.269 162.422 99.185  1.00 69.72  0  62  VAL B O   1 
ATOM   6137 C  CB  . VAL B 2 62  ? 148.164 161.027 96.402  1.00 69.72  0  62  VAL B CB  1 
ATOM   6138 C  CG1 . VAL B 2 62  ? 148.533 160.343 95.096  1.00 69.72  0  62  VAL B CG1 1 
ATOM   6139 C  CG2 . VAL B 2 62  ? 147.944 160.003 97.500  1.00 69.72  0  62  VAL B CG2 1 
ATOM   6140 N  N   . GLU B 2 63  ? 148.076 163.845 97.898  1.00 71.15  0  63  GLU B N   1 
ATOM   6141 C  CA  . GLU B 2 63  ? 147.652 164.667 99.024  1.00 71.15  0  63  GLU B CA  1 
ATOM   6142 C  C   . GLU B 2 63  ? 146.202 165.119 98.885  1.00 71.15  0  63  GLU B C   1 
ATOM   6143 O  O   . GLU B 2 63  ? 145.820 166.161 99.429  1.00 71.15  0  63  GLU B O   1 
ATOM   6144 C  CB  . GLU B 2 63  ? 148.565 165.886 99.185  1.00 71.15  0  63  GLU B CB  1 
ATOM   6145 C  CG  . GLU B 2 63  ? 148.589 166.814 97.979  1.00 71.15  0  63  GLU B CG  1 
ATOM   6146 C  CD  . GLU B 2 63  ? 149.699 166.476 97.002  1.00 71.15  0  63  GLU B CD  1 
ATOM   6147 O  OE1 . GLU B 2 63  ? 150.255 165.362 97.092  1.00 71.15  0  63  GLU B OE1 1 
ATOM   6148 O  OE2 . GLU B 2 63  ? 150.015 167.326 96.143  1.00 71.15  -1 63  GLU B OE2 1 
ATOM   6149 N  N   . LYS B 2 64  ? 145.377 164.350 98.176  1.00 71.16  0  64  LYS B N   1 
ATOM   6150 C  CA  . LYS B 2 64  ? 144.005 164.769 97.917  1.00 71.16  0  64  LYS B CA  1 
ATOM   6151 C  C   . LYS B 2 64  ? 143.149 163.541 97.652  1.00 71.16  0  64  LYS B C   1 
ATOM   6152 O  O   . LYS B 2 64  ? 143.572 162.636 96.927  1.00 71.16  0  64  LYS B O   1 
ATOM   6153 C  CB  . LYS B 2 64  ? 143.954 165.730 96.724  1.00 71.16  0  64  LYS B CB  1 
ATOM   6154 C  CG  . LYS B 2 64  ? 142.631 166.448 96.536  1.00 71.16  0  64  LYS B CG  1 
ATOM   6155 C  CD  . LYS B 2 64  ? 142.675 167.326 95.294  1.00 71.16  0  64  LYS B CD  1 
ATOM   6156 C  CE  . LYS B 2 64  ? 141.378 168.090 95.101  1.00 71.16  0  64  LYS B CE  1 
ATOM   6157 N  NZ  . LYS B 2 64  ? 141.257 169.210 96.074  1.00 71.16  1  64  LYS B NZ  1 
ATOM   6158 N  N   . LEU B 2 65  ? 141.954 163.512 98.238  1.00 69.60  0  65  LEU B N   1 
ATOM   6159 C  CA  . LEU B 2 65  ? 140.995 162.426 98.047  1.00 69.60  0  65  LEU B CA  1 
ATOM   6160 C  C   . LEU B 2 65  ? 139.645 162.986 97.616  1.00 69.60  0  65  LEU B C   1 
ATOM   6161 O  O   . LEU B 2 65  ? 138.600 162.687 98.198  1.00 69.60  0  65  LEU B O   1 
ATOM   6162 C  CB  . LEU B 2 65  ? 140.861 161.581 99.311  1.00 69.60  0  65  LEU B CB  1 
ATOM   6163 C  CG  . LEU B 2 65  ? 140.283 160.181 99.099  1.00 69.60  0  65  LEU B CG  1 
ATOM   6164 C  CD1 . LEU B 2 65  ? 140.970 159.500 97.927  1.00 69.60  0  65  LEU B CD1 1 
ATOM   6165 C  CD2 . LEU B 2 65  ? 140.406 159.341 100.358 1.00 69.60  0  65  LEU B CD2 1 
ATOM   6166 N  N   . GLU B 2 66  ? 139.667 163.840 96.595  1.00 72.83  0  66  GLU B N   1 
ATOM   6167 C  CA  . GLU B 2 66  ? 138.450 164.477 96.107  1.00 72.83  0  66  GLU B CA  1 
ATOM   6168 C  C   . GLU B 2 66  ? 137.404 163.441 95.715  1.00 72.83  0  66  GLU B C   1 
ATOM   6169 O  O   . GLU B 2 66  ? 137.705 162.444 95.054  1.00 72.83  0  66  GLU B O   1 
ATOM   6170 C  CB  . GLU B 2 66  ? 138.774 165.374 94.911  1.00 72.83  0  66  GLU B CB  1 
ATOM   6171 C  CG  . GLU B 2 66  ? 137.576 166.103 94.320  1.00 72.83  0  66  GLU B CG  1 
ATOM   6172 C  CD  . GLU B 2 66  ? 136.923 165.335 93.186  1.00 72.83  0  66  GLU B CD  1 
ATOM   6173 O  OE1 . GLU B 2 66  ? 137.631 164.567 92.502  1.00 72.83  0  66  GLU B OE1 1 
ATOM   6174 O  OE2 . GLU B 2 66  ? 135.702 165.497 92.980  1.00 72.83  -1 66  GLU B OE2 1 
ATOM   6175 N  N   . GLY B 2 67  ? 136.163 163.687 96.131  1.00 72.51  0  67  GLY B N   1 
ATOM   6176 C  CA  . GLY B 2 67  ? 135.057 162.829 95.785  1.00 72.51  0  67  GLY B CA  1 
ATOM   6177 C  C   . GLY B 2 67  ? 134.385 162.220 96.998  1.00 72.51  0  67  GLY B C   1 
ATOM   6178 O  O   . GLY B 2 67  ? 135.029 161.902 98.003  1.00 72.51  0  67  GLY B O   1 
ATOM   6179 N  N   . PRO B 2 68  ? 133.066 162.046 96.925  1.00 72.98  0  68  PRO B N   1 
ATOM   6180 C  CA  . PRO B 2 68  ? 132.344 161.389 98.023  1.00 72.98  0  68  PRO B CA  1 
ATOM   6181 C  C   . PRO B 2 68  ? 132.582 159.889 98.022  1.00 72.98  0  68  PRO B C   1 
ATOM   6182 O  O   . PRO B 2 68  ? 131.770 159.125 97.492  1.00 72.98  0  68  PRO B O   1 
ATOM   6183 C  CB  . PRO B 2 68  ? 130.873 161.728 97.737  1.00 72.98  0  68  PRO B CB  1 
ATOM   6184 C  CG  . PRO B 2 68  ? 130.902 162.804 96.678  1.00 72.98  0  68  PRO B CG  1 
ATOM   6185 C  CD  . PRO B 2 68  ? 132.150 162.566 95.899  1.00 72.98  0  68  PRO B CD  1 
ATOM   6186 N  N   . CYS B 2 69  ? 133.691 159.458 98.612  1.00 74.42  0  69  CYS B N   1 
ATOM   6187 C  CA  . CYS B 2 69  ? 134.140 158.075 98.523  1.00 74.42  0  69  CYS B CA  1 
ATOM   6188 C  C   . CYS B 2 69  ? 133.703 157.295 99.756  1.00 74.42  0  69  CYS B C   1 
ATOM   6189 O  O   . CYS B 2 69  ? 133.874 157.763 100.885 1.00 74.42  0  69  CYS B O   1 
ATOM   6190 C  CB  . CYS B 2 69  ? 135.660 158.016 98.373  1.00 74.42  0  69  CYS B CB  1 
ATOM   6191 S  SG  . CYS B 2 69  ? 136.569 159.097 99.500  1.00 74.42  0  69  CYS B SG  1 
ATOM   6192 N  N   . VAL B 2 70  ? 133.145 156.108 99.537  1.00 73.72  0  70  VAL B N   1 
ATOM   6193 C  CA  . VAL B 2 70  ? 132.698 155.235 100.617 1.00 73.72  0  70  VAL B CA  1 
ATOM   6194 C  C   . VAL B 2 70  ? 133.730 154.133 100.822 1.00 73.72  0  70  VAL B C   1 
ATOM   6195 O  O   . VAL B 2 70  ? 134.196 153.514 99.856  1.00 73.72  0  70  VAL B O   1 
ATOM   6196 C  CB  . VAL B 2 70  ? 131.297 154.661 100.330 1.00 73.72  0  70  VAL B CB  1 
ATOM   6197 C  CG1 . VAL B 2 70  ? 131.305 153.750 99.109  1.00 73.72  0  70  VAL B CG1 1 
ATOM   6198 C  CG2 . VAL B 2 70  ? 130.771 153.919 101.548 1.00 73.72  0  70  VAL B CG2 1 
ATOM   6199 N  N   . LEU B 2 71  ? 134.112 153.909 102.078 1.00 71.97  0  71  LEU B N   1 
ATOM   6200 C  CA  . LEU B 2 71  ? 135.097 152.899 102.435 1.00 71.97  0  71  LEU B CA  1 
ATOM   6201 C  C   . LEU B 2 71  ? 134.568 152.093 103.613 1.00 71.97  0  71  LEU B C   1 
ATOM   6202 O  O   . LEU B 2 71  ? 133.559 152.444 104.228 1.00 71.97  0  71  LEU B O   1 
ATOM   6203 C  CB  . LEU B 2 71  ? 136.455 153.525 102.781 1.00 71.97  0  71  LEU B CB  1 
ATOM   6204 C  CG  . LEU B 2 71  ? 137.080 154.530 101.811 1.00 71.97  0  71  LEU B CG  1 
ATOM   6205 C  CD1 . LEU B 2 71  ? 138.419 155.014 102.336 1.00 71.97  0  71  LEU B CD1 1 
ATOM   6206 C  CD2 . LEU B 2 71  ? 137.260 153.905 100.443 1.00 71.97  0  71  LEU B CD2 1 
ATOM   6207 N  N   . GLN B 2 72  ? 135.263 151.004 103.930 1.00 71.00  0  72  GLN B N   1 
ATOM   6208 C  CA  . GLN B 2 72  ? 134.869 150.109 105.008 1.00 71.00  0  72  GLN B CA  1 
ATOM   6209 C  C   . GLN B 2 72  ? 135.971 150.028 106.054 1.00 71.00  0  72  GLN B C   1 
ATOM   6210 O  O   . GLN B 2 72  ? 137.154 149.929 105.717 1.00 71.00  0  72  GLN B O   1 
ATOM   6211 C  CB  . GLN B 2 72  ? 134.554 148.706 104.480 1.00 71.00  0  72  GLN B CB  1 
ATOM   6212 N  N   . ILE B 2 73  ? 135.570 150.067 107.319 1.00 70.67  0  73  ILE B N   1 
ATOM   6213 C  CA  . ILE B 2 73  ? 136.501 149.957 108.436 1.00 70.67  0  73  ILE B CA  1 
ATOM   6214 C  C   . ILE B 2 73  ? 136.902 148.499 108.614 1.00 70.67  0  73  ILE B C   1 
ATOM   6215 O  O   . ILE B 2 73  ? 136.050 147.602 108.592 1.00 70.67  0  73  ILE B O   1 
ATOM   6216 C  CB  . ILE B 2 73  ? 135.870 150.523 109.719 1.00 70.67  0  73  ILE B CB  1 
ATOM   6217 C  CG1 . ILE B 2 73  ? 136.068 152.039 109.791 1.00 70.67  0  73  ILE B CG1 1 
ATOM   6218 C  CG2 . ILE B 2 73  ? 136.413 149.820 110.952 1.00 70.67  0  73  ILE B CG2 1 
ATOM   6219 C  CD1 . ILE B 2 73  ? 135.293 152.702 110.906 1.00 70.67  0  73  ILE B CD1 1 
ATOM   6220 N  N   . GLN B 2 74  ? 138.202 148.254 108.786 1.00 70.55  0  74  GLN B N   1 
ATOM   6221 C  CA  . GLN B 2 74  ? 138.710 146.909 109.017 1.00 70.55  0  74  GLN B CA  1 
ATOM   6222 C  C   . GLN B 2 74  ? 139.303 146.703 110.401 1.00 70.55  0  74  GLN B C   1 
ATOM   6223 O  O   . GLN B 2 74  ? 139.226 145.591 110.927 1.00 70.55  0  74  GLN B O   1 
ATOM   6224 C  CB  . GLN B 2 74  ? 139.771 146.551 107.969 1.00 70.55  0  74  GLN B CB  1 
ATOM   6225 C  CG  . GLN B 2 74  ? 139.206 146.249 106.593 1.00 70.55  0  74  GLN B CG  1 
ATOM   6226 C  CD  . GLN B 2 74  ? 138.042 145.278 106.634 1.00 70.55  0  74  GLN B CD  1 
ATOM   6227 O  OE1 . GLN B 2 74  ? 138.095 144.252 107.314 1.00 70.55  0  74  GLN B OE1 1 
ATOM   6228 N  NE2 . GLN B 2 74  ? 136.980 145.599 105.905 1.00 70.55  0  74  GLN B NE2 1 
ATOM   6229 N  N   . LYS B 2 75  ? 139.883 147.737 111.006 1.00 67.66  0  75  LYS B N   1 
ATOM   6230 C  CA  . LYS B 2 75  ? 140.486 147.602 112.324 1.00 67.66  0  75  LYS B CA  1 
ATOM   6231 C  C   . LYS B 2 75  ? 140.647 148.982 112.946 1.00 67.66  0  75  LYS B C   1 
ATOM   6232 O  O   . LYS B 2 75  ? 141.022 149.936 112.260 1.00 67.66  0  75  LYS B O   1 
ATOM   6233 C  CB  . LYS B 2 75  ? 141.843 146.892 112.247 1.00 67.66  0  75  LYS B CB  1 
ATOM   6234 C  CG  . LYS B 2 75  ? 142.456 146.571 113.600 1.00 67.66  0  75  LYS B CG  1 
ATOM   6235 C  CD  . LYS B 2 75  ? 143.758 145.803 113.449 1.00 67.66  0  75  LYS B CD  1 
ATOM   6236 C  CE  . LYS B 2 75  ? 144.329 145.412 114.803 1.00 67.66  0  75  LYS B CE  1 
ATOM   6237 N  NZ  . LYS B 2 75  ? 144.790 146.598 115.576 1.00 67.66  1  75  LYS B NZ  1 
ATOM   6238 N  N   . ILE B 2 76  ? 140.365 149.074 114.243 1.00 67.28  0  76  ILE B N   1 
ATOM   6239 C  CA  . ILE B 2 76  ? 140.477 150.314 115.002 1.00 67.28  0  76  ILE B CA  1 
ATOM   6240 C  C   . ILE B 2 76  ? 141.475 150.096 116.128 1.00 67.28  0  76  ILE B C   1 
ATOM   6241 O  O   . ILE B 2 76  ? 141.375 149.112 116.869 1.00 67.28  0  76  ILE B O   1 
ATOM   6242 C  CB  . ILE B 2 76  ? 139.118 150.765 115.568 1.00 67.28  0  76  ILE B CB  1 
ATOM   6243 C  CG1 . ILE B 2 76  ? 138.040 150.703 114.489 1.00 67.28  0  76  ILE B CG1 1 
ATOM   6244 C  CG2 . ILE B 2 76  ? 139.219 152.172 116.133 1.00 67.28  0  76  ILE B CG2 1 
ATOM   6245 C  CD1 . ILE B 2 76  ? 138.341 151.564 113.302 1.00 67.28  0  76  ILE B CD1 1 
ATOM   6246 N  N   . ARG B 2 77  ? 142.432 151.011 116.257 1.00 67.28  0  77  ARG B N   1 
ATOM   6247 C  CA  . ARG B 2 77  ? 143.420 150.945 117.325 1.00 67.28  0  77  ARG B CA  1 
ATOM   6248 C  C   . ARG B 2 77  ? 143.657 152.340 117.878 1.00 67.28  0  77  ARG B C   1 
ATOM   6249 O  O   . ARG B 2 77  ? 143.797 153.299 117.112 1.00 67.28  0  77  ARG B O   1 
ATOM   6250 C  CB  . ARG B 2 77  ? 144.738 150.341 116.829 1.00 67.28  0  77  ARG B CB  1 
ATOM   6251 C  CG  . ARG B 2 77  ? 145.715 149.996 117.941 1.00 67.28  0  77  ARG B CG  1 
ATOM   6252 C  CD  . ARG B 2 77  ? 147.147 150.299 117.533 1.00 67.28  0  77  ARG B CD  1 
ATOM   6253 N  NE  . ARG B 2 77  ? 148.102 149.932 118.571 1.00 67.28  0  77  ARG B NE  1 
ATOM   6254 C  CZ  . ARG B 2 77  ? 148.638 150.787 119.431 1.00 67.28  0  77  ARG B CZ  1 
ATOM   6255 N  NH1 . ARG B 2 77  ? 148.326 152.071 119.413 1.00 67.28  1  77  ARG B NH1 1 
ATOM   6256 N  NH2 . ARG B 2 77  ? 149.508 150.342 120.332 1.00 67.28  0  77  ARG B NH2 1 
ATOM   6257 N  N   . ASN B 2 78  ? 143.698 152.449 119.203 1.00 67.28  0  78  ASN B N   1 
ATOM   6258 C  CA  . ASN B 2 78  ? 143.978 153.718 119.862 1.00 67.28  0  78  ASN B CA  1 
ATOM   6259 C  C   . ASN B 2 78  ? 145.487 153.926 119.922 1.00 67.28  0  78  ASN B C   1 
ATOM   6260 O  O   . ASN B 2 78  ? 146.192 153.197 120.628 1.00 67.28  0  78  ASN B O   1 
ATOM   6261 C  CB  . ASN B 2 78  ? 143.370 153.730 121.263 1.00 67.28  0  78  ASN B CB  1 
ATOM   6262 C  CG  . ASN B 2 78  ? 143.321 155.119 121.871 1.00 67.28  0  78  ASN B CG  1 
ATOM   6263 O  OD1 . ASN B 2 78  ? 144.226 155.931 121.680 1.00 67.28  0  78  ASN B OD1 1 
ATOM   6264 N  ND2 . ASN B 2 78  ? 142.259 155.395 122.617 1.00 67.28  0  78  ASN B ND2 1 
ATOM   6265 N  N   . VAL B 2 79  ? 145.981 154.918 119.186 1.00 67.28  0  79  VAL B N   1 
ATOM   6266 C  CA  . VAL B 2 79  ? 147.415 155.182 119.165 1.00 67.28  0  79  VAL B CA  1 
ATOM   6267 C  C   . VAL B 2 79  ? 147.846 156.088 120.315 1.00 67.28  0  79  VAL B C   1 
ATOM   6268 O  O   . VAL B 2 79  ? 149.045 156.217 120.580 1.00 67.28  0  79  VAL B O   1 
ATOM   6269 C  CB  . VAL B 2 79  ? 147.832 155.773 117.810 1.00 67.28  0  79  VAL B CB  1 
ATOM   6270 C  CG1 . VAL B 2 79  ? 147.780 154.708 116.734 1.00 67.28  0  79  VAL B CG1 1 
ATOM   6271 C  CG2 . VAL B 2 79  ? 146.933 156.932 117.446 1.00 67.28  0  79  VAL B CG2 1 
ATOM   6272 N  N   . ALA B 2 80  ? 146.898 156.726 120.999 1.00 67.28  0  80  ALA B N   1 
ATOM   6273 C  CA  . ALA B 2 80  ? 147.216 157.519 122.178 1.00 67.28  0  80  ALA B CA  1 
ATOM   6274 C  C   . ALA B 2 80  ? 147.333 156.678 123.441 1.00 67.28  0  80  ALA B C   1 
ATOM   6275 O  O   . ALA B 2 80  ? 147.715 157.213 124.488 1.00 67.28  0  80  ALA B O   1 
ATOM   6276 C  CB  . ALA B 2 80  ? 146.160 158.607 122.382 1.00 67.28  0  80  ALA B CB  1 
ATOM   6277 N  N   . ALA B 2 81  ? 147.017 155.387 123.371 1.00 67.28  0  81  ALA B N   1 
ATOM   6278 C  CA  . ALA B 2 81  ? 147.062 154.487 124.509 1.00 67.28  0  81  ALA B CA  1 
ATOM   6279 C  C   . ALA B 2 81  ? 147.887 153.250 124.172 1.00 67.28  0  81  ALA B C   1 
ATOM   6280 O  O   . ALA B 2 81  ? 147.919 152.818 123.016 1.00 67.28  0  81  ALA B O   1 
ATOM   6281 C  CB  . ALA B 2 81  ? 145.648 154.062 124.929 1.00 67.28  0  81  ALA B CB  1 
ATOM   6282 N  N   . PRO B 2 82  ? 148.562 152.659 125.153 1.00 70.31  0  82  PRO B N   1 
ATOM   6283 C  CA  . PRO B 2 82  ? 149.393 151.482 124.881 1.00 70.31  0  82  PRO B CA  1 
ATOM   6284 C  C   . PRO B 2 82  ? 148.545 150.230 124.690 1.00 70.31  0  82  PRO B C   1 
ATOM   6285 O  O   . PRO B 2 82  ? 147.333 150.218 124.908 1.00 70.31  0  82  PRO B O   1 
ATOM   6286 C  CB  . PRO B 2 82  ? 150.289 151.363 126.120 1.00 70.31  0  82  PRO B CB  1 
ATOM   6287 C  CG  . PRO B 2 82  ? 149.732 152.295 127.139 1.00 70.31  0  82  PRO B CG  1 
ATOM   6288 C  CD  . PRO B 2 82  ? 148.574 153.048 126.573 1.00 70.31  0  82  PRO B CD  1 
ATOM   6289 N  N   . LYS B 2 83  ? 149.221 149.159 124.268 1.00 74.01  0  83  LYS B N   1 
ATOM   6290 C  CA  . LYS B 2 83  ? 148.555 147.900 123.953 1.00 74.01  0  83  LYS B CA  1 
ATOM   6291 C  C   . LYS B 2 83  ? 148.053 147.157 125.183 1.00 74.01  0  83  LYS B C   1 
ATOM   6292 O  O   . LYS B 2 83  ? 147.343 146.158 125.030 1.00 74.01  0  83  LYS B O   1 
ATOM   6293 C  CB  . LYS B 2 83  ? 149.497 146.992 123.161 1.00 74.01  0  83  LYS B CB  1 
ATOM   6294 C  CG  . LYS B 2 83  ? 149.678 147.398 121.709 1.00 74.01  0  83  LYS B CG  1 
ATOM   6295 C  CD  . LYS B 2 83  ? 150.707 146.525 121.010 1.00 74.01  0  83  LYS B CD  1 
ATOM   6296 C  CE  . LYS B 2 83  ? 150.187 145.111 120.809 1.00 74.01  0  83  LYS B CE  1 
ATOM   6297 N  NZ  . LYS B 2 83  ? 151.141 144.274 120.031 1.00 74.01  1  83  LYS B NZ  1 
ATOM   6298 N  N   . ASP B 2 84  ? 148.407 147.597 126.389 1.00 78.11  0  84  ASP B N   1 
ATOM   6299 C  CA  . ASP B 2 84  ? 147.969 146.898 127.590 1.00 78.11  0  84  ASP B CA  1 
ATOM   6300 C  C   . ASP B 2 84  ? 146.732 147.518 128.224 1.00 78.11  0  84  ASP B C   1 
ATOM   6301 O  O   . ASP B 2 84  ? 146.010 146.828 128.953 1.00 78.11  0  84  ASP B O   1 
ATOM   6302 C  CB  . ASP B 2 84  ? 149.103 146.852 128.619 1.00 78.11  0  84  ASP B CB  1 
ATOM   6303 C  CG  . ASP B 2 84  ? 149.791 148.192 128.791 1.00 78.11  0  84  ASP B CG  1 
ATOM   6304 O  OD1 . ASP B 2 84  ? 149.284 149.197 128.251 1.00 78.11  0  84  ASP B OD1 1 
ATOM   6305 O  OD2 . ASP B 2 84  ? 150.840 148.239 129.466 1.00 78.11  -1 84  ASP B OD2 1 
ATOM   6306 N  N   . ASN B 2 85  ? 146.466 148.800 127.968 1.00 79.66  0  85  ASN B N   1 
ATOM   6307 C  CA  . ASN B 2 85  ? 145.337 149.492 128.582 1.00 79.66  0  85  ASN B CA  1 
ATOM   6308 C  C   . ASN B 2 85  ? 144.205 149.756 127.593 1.00 79.66  0  85  ASN B C   1 
ATOM   6309 O  O   . ASN B 2 85  ? 143.067 149.339 127.826 1.00 79.66  0  85  ASN B O   1 
ATOM   6310 C  CB  . ASN B 2 85  ? 145.814 150.810 129.207 1.00 79.66  0  85  ASN B CB  1 
ATOM   6311 C  CG  . ASN B 2 85  ? 146.583 150.598 130.496 1.00 79.66  0  85  ASN B CG  1 
ATOM   6312 O  OD1 . ASN B 2 85  ? 147.811 150.676 130.519 1.00 79.66  0  85  ASN B OD1 1 
ATOM   6313 N  ND2 . ASN B 2 85  ? 145.862 150.330 131.578 1.00 79.66  0  85  ASN B ND2 1 
ATOM   6314 N  N   . GLU B 2 86  ? 144.501 150.461 126.497 1.00 81.59  0  86  GLU B N   1 
ATOM   6315 C  CA  . GLU B 2 86  ? 143.515 150.865 125.494 1.00 81.59  0  86  GLU B CA  1 
ATOM   6316 C  C   . GLU B 2 86  ? 142.428 151.768 126.069 1.00 81.59  0  86  GLU B C   1 
ATOM   6317 O  O   . GLU B 2 86  ? 141.490 152.140 125.356 1.00 81.59  0  86  GLU B O   1 
ATOM   6318 C  CB  . GLU B 2 86  ? 142.869 149.648 124.821 1.00 81.59  0  86  GLU B CB  1 
ATOM   6319 C  CG  . GLU B 2 86  ? 143.720 148.975 123.755 1.00 81.59  0  86  GLU B CG  1 
ATOM   6320 C  CD  . GLU B 2 86  ? 144.607 147.876 124.300 1.00 81.59  0  86  GLU B CD  1 
ATOM   6321 O  OE1 . GLU B 2 86  ? 144.545 147.599 125.515 1.00 81.59  0  86  GLU B OE1 1 
ATOM   6322 O  OE2 . GLU B 2 86  ? 145.358 147.279 123.502 1.00 81.59  -1 86  GLU B OE2 1 
ATOM   6323 N  N   . GLU B 2 87  ? 142.537 152.130 127.349 1.00 82.99  0  87  GLU B N   1 
ATOM   6324 C  CA  . GLU B 2 87  ? 141.532 152.965 127.990 1.00 82.99  0  87  GLU B CA  1 
ATOM   6325 C  C   . GLU B 2 87  ? 142.110 154.008 128.935 1.00 82.99  0  87  GLU B C   1 
ATOM   6326 O  O   . GLU B 2 87  ? 141.334 154.695 129.607 1.00 82.99  0  87  GLU B O   1 
ATOM   6327 C  CB  . GLU B 2 87  ? 140.522 152.095 128.761 1.00 82.99  0  87  GLU B CB  1 
ATOM   6328 C  CG  . GLU B 2 87  ? 139.595 151.273 127.878 1.00 82.99  0  87  GLU B CG  1 
ATOM   6329 C  CD  . GLU B 2 87  ? 138.640 152.135 127.074 1.00 82.99  0  87  GLU B CD  1 
ATOM   6330 O  OE1 . GLU B 2 87  ? 138.235 153.205 127.576 1.00 82.99  0  87  GLU B OE1 1 
ATOM   6331 O  OE2 . GLU B 2 87  ? 138.295 151.743 125.940 1.00 82.99  -1 87  GLU B OE2 1 
ATOM   6332 N  N   . SER B 2 88  ? 143.431 154.147 129.018 1.00 79.21  0  88  SER B N   1 
ATOM   6333 C  CA  . SER B 2 88  ? 144.026 155.108 129.937 1.00 79.21  0  88  SER B CA  1 
ATOM   6334 C  C   . SER B 2 88  ? 143.707 156.530 129.493 1.00 79.21  0  88  SER B C   1 
ATOM   6335 O  O   . SER B 2 88  ? 143.982 156.913 128.352 1.00 79.21  0  88  SER B O   1 
ATOM   6336 C  CB  . SER B 2 88  ? 145.538 154.903 130.013 1.00 79.21  0  88  SER B CB  1 
ATOM   6337 O  OG  . SER B 2 88  ? 146.127 154.973 128.727 1.00 79.21  0  88  SER B OG  1 
ATOM   6338 N  N   . GLN B 2 89  ? 143.126 157.311 130.398 1.00 77.95  0  89  GLN B N   1 
ATOM   6339 C  CA  . GLN B 2 89  ? 142.772 158.700 130.108 1.00 77.95  0  89  GLN B CA  1 
ATOM   6340 C  C   . GLN B 2 89  ? 143.889 159.659 130.507 1.00 77.95  0  89  GLN B C   1 
ATOM   6341 O  O   . GLN B 2 89  ? 143.675 160.640 131.218 1.00 77.95  0  89  GLN B O   1 
ATOM   6342 C  CB  . GLN B 2 89  ? 141.466 159.059 130.806 1.00 77.95  0  89  GLN B CB  1 
ATOM   6343 C  CG  . GLN B 2 89  ? 140.260 158.285 130.299 1.00 77.95  0  89  GLN B CG  1 
ATOM   6344 C  CD  . GLN B 2 89  ? 140.040 158.462 128.809 1.00 77.95  0  89  GLN B CD  1 
ATOM   6345 O  OE1 . GLN B 2 89  ? 140.293 157.552 128.020 1.00 77.95  0  89  GLN B OE1 1 
ATOM   6346 N  NE2 . GLN B 2 89  ? 139.565 159.639 128.417 1.00 77.95  0  89  GLN B NE2 1 
ATOM   6347 N  N   . ALA B 2 90  ? 145.103 159.375 130.041 1.00 71.19  0  90  ALA B N   1 
ATOM   6348 C  CA  . ALA B 2 90  ? 146.242 160.261 130.230 1.00 71.19  0  90  ALA B CA  1 
ATOM   6349 C  C   . ALA B 2 90  ? 146.561 161.068 128.982 1.00 71.19  0  90  ALA B C   1 
ATOM   6350 O  O   . ALA B 2 90  ? 147.491 161.880 129.003 1.00 71.19  0  90  ALA B O   1 
ATOM   6351 C  CB  . ALA B 2 90  ? 147.474 159.458 130.658 1.00 71.19  0  90  ALA B CB  1 
ATOM   6352 N  N   . ALA B 2 91  ? 145.813 160.860 127.898 1.00 67.28  0  91  ALA B N   1 
ATOM   6353 C  CA  . ALA B 2 91  ? 145.991 161.563 126.645 1.00 67.28  0  91  ALA B CA  1 
ATOM   6354 C  C   . ALA B 2 91  ? 144.667 161.505 125.902 1.00 67.28  0  91  ALA B C   1 
ATOM   6355 O  O   . ALA B 2 91  ? 143.971 160.482 125.983 1.00 67.28  0  91  ALA B O   1 
ATOM   6356 C  CB  . ALA B 2 91  ? 147.100 160.947 125.788 1.00 67.28  0  91  ALA B CB  1 
ATOM   6357 N  N   . PRO B 2 92  ? 144.281 162.570 125.202 1.00 67.28  0  92  PRO B N   1 
ATOM   6358 C  CA  . PRO B 2 92  ? 143.070 162.501 124.378 1.00 67.28  0  92  PRO B CA  1 
ATOM   6359 C  C   . PRO B 2 92  ? 143.193 161.390 123.349 1.00 67.28  0  92  PRO B C   1 
ATOM   6360 O  O   . PRO B 2 92  ? 144.228 161.236 122.696 1.00 67.28  0  92  PRO B O   1 
ATOM   6361 C  CB  . PRO B 2 92  ? 143.008 163.882 123.718 1.00 67.28  0  92  PRO B CB  1 
ATOM   6362 C  CG  . PRO B 2 92  ? 143.824 164.764 124.600 1.00 67.28  0  92  PRO B CG  1 
ATOM   6363 C  CD  . PRO B 2 92  ? 144.913 163.897 125.149 1.00 67.28  0  92  PRO B CD  1 
ATOM   6364 N  N   . ARG B 2 93  ? 142.125 160.613 123.204 1.00 67.28  0  93  ARG B N   1 
ATOM   6365 C  CA  . ARG B 2 93  ? 142.194 159.432 122.357 1.00 67.28  0  93  ARG B CA  1 
ATOM   6366 C  C   . ARG B 2 93  ? 142.189 159.835 120.889 1.00 67.28  0  93  ARG B C   1 
ATOM   6367 O  O   . ARG B 2 93  ? 141.404 160.688 120.464 1.00 67.28  0  93  ARG B O   1 
ATOM   6368 C  CB  . ARG B 2 93  ? 141.043 158.474 122.672 1.00 67.28  0  93  ARG B CB  1 
ATOM   6369 C  CG  . ARG B 2 93  ? 139.667 158.886 122.175 1.00 67.28  0  93  ARG B CG  1 
ATOM   6370 C  CD  . ARG B 2 93  ? 139.007 157.726 121.444 1.00 67.28  0  93  ARG B CD  1 
ATOM   6371 N  NE  . ARG B 2 93  ? 137.605 157.980 121.135 1.00 67.28  0  93  ARG B NE  1 
ATOM   6372 C  CZ  . ARG B 2 93  ? 137.181 158.703 120.108 1.00 67.28  0  93  ARG B CZ  1 
ATOM   6373 N  NH1 . ARG B 2 93  ? 138.028 159.264 119.262 1.00 67.28  1  93  ARG B NH1 1 
ATOM   6374 N  NH2 . ARG B 2 93  ? 135.874 158.862 119.923 1.00 67.28  0  93  ARG B NH2 1 
ATOM   6375 N  N   . MET B 2 94  ? 143.099 159.244 120.124 1.00 67.28  0  94  MET B N   1 
ATOM   6376 C  CA  . MET B 2 94  ? 143.209 159.473 118.692 1.00 67.28  0  94  MET B CA  1 
ATOM   6377 C  C   . MET B 2 94  ? 143.204 158.121 117.995 1.00 67.28  0  94  MET B C   1 
ATOM   6378 O  O   . MET B 2 94  ? 143.920 157.204 118.409 1.00 67.28  0  94  MET B O   1 
ATOM   6379 C  CB  . MET B 2 94  ? 144.471 160.276 118.363 1.00 67.28  0  94  MET B CB  1 
ATOM   6380 C  CG  . MET B 2 94  ? 144.648 160.612 116.895 1.00 67.28  0  94  MET B CG  1 
ATOM   6381 S  SD  . MET B 2 94  ? 146.132 161.590 116.584 1.00 67.28  0  94  MET B SD  1 
ATOM   6382 C  CE  . MET B 2 94  ? 147.424 160.383 116.843 1.00 67.28  0  94  MET B CE  1 
ATOM   6383 N  N   . LEU B 2 95  ? 142.385 157.995 116.957 1.00 67.34  0  95  LEU B N   1 
ATOM   6384 C  CA  . LEU B 2 95  ? 142.090 156.708 116.344 1.00 67.34  0  95  LEU B CA  1 
ATOM   6385 C  C   . LEU B 2 95  ? 142.840 156.561 115.028 1.00 67.34  0  95  LEU B C   1 
ATOM   6386 O  O   . LEU B 2 95  ? 142.855 157.485 114.205 1.00 67.34  0  95  LEU B O   1 
ATOM   6387 C  CB  . LEU B 2 95  ? 140.586 156.548 116.116 1.00 67.34  0  95  LEU B CB  1 
ATOM   6388 C  CG  . LEU B 2 95  ? 139.760 156.187 117.352 1.00 67.34  0  95  LEU B CG  1 
ATOM   6389 C  CD1 . LEU B 2 95  ? 138.364 155.744 116.954 1.00 67.34  0  95  LEU B CD1 1 
ATOM   6390 C  CD2 . LEU B 2 95  ? 140.454 155.111 118.174 1.00 67.34  0  95  LEU B CD2 1 
ATOM   6391 N  N   . ARG B 2 96  ? 143.462 155.398 114.842 1.00 67.28  0  96  ARG B N   1 
ATOM   6392 C  CA  . ARG B 2 96  ? 144.115 155.027 113.589 1.00 67.28  0  96  ARG B CA  1 
ATOM   6393 C  C   . ARG B 2 96  ? 143.149 154.119 112.835 1.00 67.28  0  96  ARG B C   1 
ATOM   6394 O  O   . ARG B 2 96  ? 143.094 152.910 113.060 1.00 67.28  0  96  ARG B O   1 
ATOM   6395 C  CB  . ARG B 2 96  ? 145.453 154.343 113.844 1.00 67.28  0  96  ARG B CB  1 
ATOM   6396 C  CG  . ARG B 2 96  ? 146.305 154.198 112.597 1.00 67.28  0  96  ARG B CG  1 
ATOM   6397 C  CD  . ARG B 2 96  ? 147.622 153.492 112.877 1.00 67.28  0  96  ARG B CD  1 
ATOM   6398 N  NE  . ARG B 2 96  ? 147.446 152.058 113.073 1.00 67.28  0  96  ARG B NE  1 
ATOM   6399 C  CZ  . ARG B 2 96  ? 147.937 151.375 114.098 1.00 67.28  0  96  ARG B CZ  1 
ATOM   6400 N  NH1 . ARG B 2 96  ? 148.659 151.963 115.038 1.00 67.28  1  96  ARG B NH1 1 
ATOM   6401 N  NH2 . ARG B 2 96  ? 147.703 150.069 114.179 1.00 67.28  0  96  ARG B NH2 1 
ATOM   6402 N  N   . LEU B 2 97  ? 142.382 154.716 111.930 1.00 68.94  0  97  LEU B N   1 
ATOM   6403 C  CA  . LEU B 2 97  ? 141.346 153.999 111.200 1.00 68.94  0  97  LEU B CA  1 
ATOM   6404 C  C   . LEU B 2 97  ? 141.968 153.278 110.010 1.00 68.94  0  97  LEU B C   1 
ATOM   6405 O  O   . LEU B 2 97  ? 142.485 153.923 109.093 1.00 68.94  0  97  LEU B O   1 
ATOM   6406 C  CB  . LEU B 2 97  ? 140.275 154.975 110.719 1.00 68.94  0  97  LEU B CB  1 
ATOM   6407 C  CG  . LEU B 2 97  ? 139.526 155.825 111.749 1.00 68.94  0  97  LEU B CG  1 
ATOM   6408 C  CD1 . LEU B 2 97  ? 138.632 156.834 111.048 1.00 68.94  0  97  LEU B CD1 1 
ATOM   6409 C  CD2 . LEU B 2 97  ? 138.719 154.975 112.700 1.00 68.94  0  97  LEU B CD2 1 
ATOM   6410 N  N   . GLN B 2 98  ? 141.919 151.951 110.015 1.00 70.03  0  98  GLN B N   1 
ATOM   6411 C  CA  . GLN B 2 98  ? 142.292 151.176 108.840 1.00 70.03  0  98  GLN B CA  1 
ATOM   6412 C  C   . GLN B 2 98  ? 141.059 151.037 107.956 1.00 70.03  0  98  GLN B C   1 
ATOM   6413 O  O   . GLN B 2 98  ? 140.056 150.447 108.372 1.00 70.03  0  98  GLN B O   1 
ATOM   6414 C  CB  . GLN B 2 98  ? 142.845 149.807 109.233 1.00 70.03  0  98  GLN B CB  1 
ATOM   6415 C  CG  . GLN B 2 98  ? 144.305 149.832 109.657 1.00 70.03  0  98  GLN B CG  1 
ATOM   6416 C  CD  . GLN B 2 98  ? 144.919 148.448 109.727 1.00 70.03  0  98  GLN B CD  1 
ATOM   6417 O  OE1 . GLN B 2 98  ? 144.263 147.449 109.434 1.00 70.03  0  98  GLN B OE1 1 
ATOM   6418 N  NE2 . GLN B 2 98  ? 146.187 148.383 110.116 1.00 70.03  0  98  GLN B NE2 1 
ATOM   6419 N  N   . MET B 2 99  ? 141.123 151.595 106.751 1.00 70.45  0  99  MET B N   1 
ATOM   6420 C  CA  . MET B 2 99  ? 139.975 151.664 105.865 1.00 70.45  0  99  MET B CA  1 
ATOM   6421 C  C   . MET B 2 99  ? 140.326 150.980 104.552 1.00 70.45  0  99  MET B C   1 
ATOM   6422 O  O   . MET B 2 99  ? 141.497 150.892 104.177 1.00 70.45  0  99  MET B O   1 
ATOM   6423 C  CB  . MET B 2 99  ? 139.561 153.123 105.632 1.00 70.45  0  99  MET B CB  1 
ATOM   6424 C  CG  . MET B 2 99  ? 139.032 153.798 106.893 1.00 70.45  0  99  MET B CG  1 
ATOM   6425 S  SD  . MET B 2 99  ? 138.607 155.541 106.712 1.00 70.45  0  99  MET B SD  1 
ATOM   6426 C  CE  . MET B 2 99  ? 137.140 155.444 105.696 1.00 70.45  0  99  MET B CE  1 
ATOM   6427 N  N   . THR B 2 100 ? 139.310 150.464 103.869 1.00 73.49  0  100 THR B N   1 
ATOM   6428 C  CA  . THR B 2 100 ? 139.545 149.709 102.648 1.00 73.49  0  100 THR B CA  1 
ATOM   6429 C  C   . THR B 2 100 ? 138.438 149.965 101.640 1.00 73.49  0  100 THR B C   1 
ATOM   6430 O  O   . THR B 2 100 ? 137.316 150.335 101.996 1.00 73.49  0  100 THR B O   1 
ATOM   6431 C  CB  . THR B 2 100 ? 139.648 148.201 102.924 1.00 73.49  0  100 THR B CB  1 
ATOM   6432 O  OG1 . THR B 2 100 ? 140.063 147.524 101.731 1.00 73.49  0  100 THR B OG1 1 
ATOM   6433 C  CG2 . THR B 2 100 ? 138.305 147.645 103.372 1.00 73.49  0  100 THR B CG2 1 
ATOM   6434 N  N   . ASP B 2 101 ? 138.781 149.777 100.369 1.00 77.26  0  101 ASP B N   1 
ATOM   6435 C  CA  . ASP B 2 101 ? 137.825 149.747 99.274  1.00 77.26  0  101 ASP B CA  1 
ATOM   6436 C  C   . ASP B 2 101 ? 137.551 148.327 98.799  1.00 77.26  0  101 ASP B C   1 
ATOM   6437 O  O   . ASP B 2 101 ? 136.820 148.137 97.823  1.00 77.26  0  101 ASP B O   1 
ATOM   6438 C  CB  . ASP B 2 101 ? 138.342 150.596 98.108  1.00 77.26  0  101 ASP B CB  1 
ATOM   6439 C  CG  . ASP B 2 101 ? 137.264 150.923 97.097  1.00 77.26  0  101 ASP B CG  1 
ATOM   6440 O  OD1 . ASP B 2 101 ? 136.068 150.777 97.429  1.00 77.26  0  101 ASP B OD1 1 
ATOM   6441 O  OD2 . ASP B 2 101 ? 137.615 151.315 95.965  1.00 77.26  -1 101 ASP B OD2 1 
ATOM   6442 N  N   . GLY B 2 102 ? 138.114 147.327 99.474  1.00 79.21  0  102 GLY B N   1 
ATOM   6443 C  CA  . GLY B 2 102 ? 138.107 145.967 98.990  1.00 79.21  0  102 GLY B CA  1 
ATOM   6444 C  C   . GLY B 2 102 ? 139.240 145.641 98.044  1.00 79.21  0  102 GLY B C   1 
ATOM   6445 O  O   . GLY B 2 102 ? 139.469 144.458 97.760  1.00 79.21  0  102 GLY B O   1 
ATOM   6446 N  N   . HIS B 2 103 ? 139.955 146.651 97.549  1.00 76.44  0  103 HIS B N   1 
ATOM   6447 C  CA  . HIS B 2 103 ? 141.088 146.448 96.655  1.00 76.44  0  103 HIS B CA  1 
ATOM   6448 C  C   . HIS B 2 103 ? 142.388 146.958 97.263  1.00 76.44  0  103 HIS B C   1 
ATOM   6449 O  O   . HIS B 2 103 ? 143.374 146.216 97.309  1.00 76.44  0  103 HIS B O   1 
ATOM   6450 C  CB  . HIS B 2 103 ? 140.812 147.131 95.309  1.00 76.44  0  103 HIS B CB  1 
ATOM   6451 C  CG  . HIS B 2 103 ? 139.663 146.538 94.555  1.00 76.44  0  103 HIS B CG  1 
ATOM   6452 N  ND1 . HIS B 2 103 ? 138.358 146.640 94.986  1.00 76.44  0  103 HIS B ND1 1 
ATOM   6453 C  CD2 . HIS B 2 103 ? 139.622 145.840 93.395  1.00 76.44  0  103 HIS B CD2 1 
ATOM   6454 C  CE1 . HIS B 2 103 ? 137.563 146.029 94.126  1.00 76.44  0  103 HIS B CE1 1 
ATOM   6455 N  NE2 . HIS B 2 103 ? 138.305 145.535 93.152  1.00 76.44  0  103 HIS B NE2 1 
ATOM   6456 N  N   . ILE B 2 104 ? 142.421 148.204 97.732  1.00 72.06  0  104 ILE B N   1 
ATOM   6457 C  CA  . ILE B 2 104 ? 143.608 148.805 98.332  1.00 72.06  0  104 ILE B CA  1 
ATOM   6458 C  C   . ILE B 2 104 ? 143.241 149.292 99.726  1.00 72.06  0  104 ILE B C   1 
ATOM   6459 O  O   . ILE B 2 104 ? 142.206 149.942 99.909  1.00 72.06  0  104 ILE B O   1 
ATOM   6460 C  CB  . ILE B 2 104 ? 144.165 149.963 97.481  1.00 72.06  0  104 ILE B CB  1 
ATOM   6461 C  CG1 . ILE B 2 104 ? 144.624 149.471 96.105  1.00 72.06  0  104 ILE B CG1 1 
ATOM   6462 C  CG2 . ILE B 2 104 ? 145.313 150.655 98.202  1.00 72.06  0  104 ILE B CG2 1 
ATOM   6463 C  CD1 . ILE B 2 104 ? 143.548 149.480 95.041  1.00 72.06  0  104 ILE B CD1 1 
ATOM   6464 N  N   . SER B 2 105 ? 144.086 148.977 100.705 1.00 70.06  0  105 SER B N   1 
ATOM   6465 C  CA  . SER B 2 105 ? 143.858 149.354 102.093 1.00 70.06  0  105 SER B CA  1 
ATOM   6466 C  C   . SER B 2 105 ? 144.652 150.615 102.412 1.00 70.06  0  105 SER B C   1 
ATOM   6467 O  O   . SER B 2 105 ? 145.872 150.650 102.223 1.00 70.06  0  105 SER B O   1 
ATOM   6468 C  CB  . SER B 2 105 ? 144.256 148.219 103.037 1.00 70.06  0  105 SER B CB  1 
ATOM   6469 O  OG  . SER B 2 105 ? 145.652 147.983 102.991 1.00 70.06  0  105 SER B OG  1 
ATOM   6470 N  N   . CYS B 2 106 ? 143.959 151.642 102.893 1.00 70.82  0  106 CYS B N   1 
ATOM   6471 C  CA  . CYS B 2 106 ? 144.568 152.892 103.317 1.00 70.82  0  106 CYS B CA  1 
ATOM   6472 C  C   . CYS B 2 106 ? 144.389 153.072 104.820 1.00 70.82  0  106 CYS B C   1 
ATOM   6473 O  O   . CYS B 2 106 ? 143.651 152.335 105.483 1.00 70.82  0  106 CYS B O   1 
ATOM   6474 C  CB  . CYS B 2 106 ? 143.962 154.079 102.560 1.00 70.82  0  106 CYS B CB  1 
ATOM   6475 S  SG  . CYS B 2 106 ? 142.204 154.344 102.871 1.00 70.82  0  106 CYS B SG  1 
ATOM   6476 N  N   . THR B 2 107 ? 145.087 154.066 105.358 1.00 68.06  0  107 THR B N   1 
ATOM   6477 C  CA  . THR B 2 107 ? 145.033 154.370 106.778 1.00 68.06  0  107 THR B CA  1 
ATOM   6478 C  C   . THR B 2 107 ? 144.743 155.851 106.975 1.00 68.06  0  107 THR B C   1 
ATOM   6479 O  O   . THR B 2 107 ? 145.254 156.699 106.239 1.00 68.06  0  107 THR B O   1 
ATOM   6480 C  CB  . THR B 2 107 ? 146.342 153.987 107.475 1.00 68.06  0  107 THR B CB  1 
ATOM   6481 O  OG1 . THR B 2 107 ? 146.741 152.677 107.056 1.00 68.06  0  107 THR B OG1 1 
ATOM   6482 C  CG2 . THR B 2 107 ? 146.164 153.992 108.983 1.00 68.06  0  107 THR B CG2 1 
ATOM   6483 N  N   . ALA B 2 108 ? 143.911 156.154 107.966 1.00 67.52  0  108 ALA B N   1 
ATOM   6484 C  CA  . ALA B 2 108 ? 143.551 157.519 108.308 1.00 67.52  0  108 ALA B CA  1 
ATOM   6485 C  C   . ALA B 2 108 ? 143.784 157.735 109.795 1.00 67.52  0  108 ALA B C   1 
ATOM   6486 O  O   . ALA B 2 108 ? 143.832 156.787 110.579 1.00 67.52  0  108 ALA B O   1 
ATOM   6487 C  CB  . ALA B 2 108 ? 142.091 157.820 107.953 1.00 67.52  0  108 ALA B CB  1 
ATOM   6488 N  N   . VAL B 2 109 ? 143.933 158.998 110.182 1.00 67.28  0  109 VAL B N   1 
ATOM   6489 C  CA  . VAL B 2 109 ? 144.124 159.362 111.578 1.00 67.28  0  109 VAL B CA  1 
ATOM   6490 C  C   . VAL B 2 109 ? 143.059 160.379 111.966 1.00 67.28  0  109 VAL B C   1 
ATOM   6491 O  O   . VAL B 2 109 ? 142.724 161.280 111.186 1.00 67.28  0  109 VAL B O   1 
ATOM   6492 C  CB  . VAL B 2 109 ? 145.546 159.905 111.844 1.00 67.28  0  109 VAL B CB  1 
ATOM   6493 C  CG1 . VAL B 2 109 ? 145.788 161.210 111.104 1.00 67.28  0  109 VAL B CG1 1 
ATOM   6494 C  CG2 . VAL B 2 109 ? 145.784 160.075 113.336 1.00 67.28  0  109 VAL B CG2 1 
ATOM   6495 N  N   . GLU B 2 110 ? 142.507 160.208 113.166 1.00 68.22  0  110 GLU B N   1 
ATOM   6496 C  CA  . GLU B 2 110 ? 141.484 161.106 113.690 1.00 68.22  0  110 GLU B CA  1 
ATOM   6497 C  C   . GLU B 2 110 ? 142.144 162.418 114.100 1.00 68.22  0  110 GLU B C   1 
ATOM   6498 O  O   . GLU B 2 110 ? 142.782 162.497 115.154 1.00 68.22  0  110 GLU B O   1 
ATOM   6499 C  CB  . GLU B 2 110 ? 140.770 160.450 114.867 1.00 68.22  0  110 GLU B CB  1 
ATOM   6500 C  CG  . GLU B 2 110 ? 139.489 161.136 115.291 1.00 68.22  0  110 GLU B CG  1 
ATOM   6501 C  CD  . GLU B 2 110 ? 139.023 160.691 116.664 1.00 68.22  0  110 GLU B CD  1 
ATOM   6502 O  OE1 . GLU B 2 110 ? 139.696 159.833 117.271 1.00 68.22  0  110 GLU B OE1 1 
ATOM   6503 O  OE2 . GLU B 2 110 ? 137.987 161.202 117.138 1.00 68.22  -1 110 GLU B OE2 1 
ATOM   6504 N  N   . PHE B 2 111 ? 141.988 163.450 113.275 1.00 67.28  0  111 PHE B N   1 
ATOM   6505 C  CA  . PHE B 2 111 ? 142.627 164.738 113.507 1.00 67.28  0  111 PHE B CA  1 
ATOM   6506 C  C   . PHE B 2 111 ? 141.839 165.630 114.457 1.00 67.28  0  111 PHE B C   1 
ATOM   6507 O  O   . PHE B 2 111 ? 142.281 166.745 114.751 1.00 67.28  0  111 PHE B O   1 
ATOM   6508 C  CB  . PHE B 2 111 ? 142.840 165.464 112.175 1.00 67.28  0  111 PHE B CB  1 
ATOM   6509 C  CG  . PHE B 2 111 ? 143.961 166.460 112.201 1.00 67.28  0  111 PHE B CG  1 
ATOM   6510 C  CD1 . PHE B 2 111 ? 145.271 166.044 112.362 1.00 67.28  0  111 PHE B CD1 1 
ATOM   6511 C  CD2 . PHE B 2 111 ? 143.706 167.813 112.061 1.00 67.28  0  111 PHE B CD2 1 
ATOM   6512 C  CE1 . PHE B 2 111 ? 146.305 166.958 112.386 1.00 67.28  0  111 PHE B CE1 1 
ATOM   6513 C  CE2 . PHE B 2 111 ? 144.736 168.733 112.084 1.00 67.28  0  111 PHE B CE2 1 
ATOM   6514 C  CZ  . PHE B 2 111 ? 146.037 168.304 112.246 1.00 67.28  0  111 PHE B CZ  1 
ATOM   6515 N  N   . SER B 2 112 ? 140.694 165.166 114.940 1.00 68.73  0  112 SER B N   1 
ATOM   6516 C  CA  . SER B 2 112 ? 139.845 165.921 115.853 1.00 68.73  0  112 SER B CA  1 
ATOM   6517 C  C   . SER B 2 112 ? 139.160 164.912 116.768 1.00 68.73  0  112 SER B C   1 
ATOM   6518 O  O   . SER B 2 112 ? 139.612 163.770 116.896 1.00 68.73  0  112 SER B O   1 
ATOM   6519 C  CB  . SER B 2 112 ? 138.855 166.799 115.069 1.00 68.73  0  112 SER B CB  1 
ATOM   6520 O  OG  . SER B 2 112 ? 139.518 167.891 114.457 1.00 68.73  0  112 SER B OG  1 
ATOM   6521 N  N   . TYR B 2 113 ? 138.087 165.330 117.430 1.00 69.90  0  113 TYR B N   1 
ATOM   6522 C  CA  . TYR B 2 113 ? 137.260 164.418 118.211 1.00 69.90  0  113 TYR B CA  1 
ATOM   6523 C  C   . TYR B 2 113 ? 136.074 163.998 117.351 1.00 69.90  0  113 TYR B C   1 
ATOM   6524 O  O   . TYR B 2 113 ? 135.164 164.795 117.102 1.00 69.90  0  113 TYR B O   1 
ATOM   6525 C  CB  . TYR B 2 113 ? 136.795 165.060 119.515 1.00 69.90  0  113 TYR B CB  1 
ATOM   6526 C  CG  . TYR B 2 113 ? 136.304 164.051 120.530 1.00 69.90  0  113 TYR B CG  1 
ATOM   6527 C  CD1 . TYR B 2 113 ? 135.002 163.572 120.487 1.00 69.90  0  113 TYR B CD1 1 
ATOM   6528 C  CD2 . TYR B 2 113 ? 137.145 163.572 121.524 1.00 69.90  0  113 TYR B CD2 1 
ATOM   6529 C  CE1 . TYR B 2 113 ? 134.550 162.648 121.408 1.00 69.90  0  113 TYR B CE1 1 
ATOM   6530 C  CE2 . TYR B 2 113 ? 136.702 162.648 122.450 1.00 69.90  0  113 TYR B CE2 1 
ATOM   6531 C  CZ  . TYR B 2 113 ? 135.403 162.190 122.387 1.00 69.90  0  113 TYR B CZ  1 
ATOM   6532 O  OH  . TYR B 2 113 ? 134.956 161.269 123.307 1.00 69.90  0  113 TYR B OH  1 
ATOM   6533 N  N   . MET B 2 114 ? 136.090 162.748 116.899 1.00 72.11  0  114 MET B N   1 
ATOM   6534 C  CA  . MET B 2 114 ? 135.013 162.179 116.094 1.00 72.11  0  114 MET B CA  1 
ATOM   6535 C  C   . MET B 2 114 ? 134.155 161.321 117.016 1.00 72.11  0  114 MET B C   1 
ATOM   6536 O  O   . MET B 2 114 ? 134.508 160.181 117.329 1.00 72.11  0  114 MET B O   1 
ATOM   6537 C  CB  . MET B 2 114 ? 135.578 161.368 114.932 1.00 72.11  0  114 MET B CB  1 
ATOM   6538 C  CG  . MET B 2 114 ? 136.076 162.211 113.772 1.00 72.11  0  114 MET B CG  1 
ATOM   6539 S  SD  . MET B 2 114 ? 136.101 161.299 112.219 1.00 72.11  0  114 MET B SD  1 
ATOM   6540 C  CE  . MET B 2 114 ? 136.929 159.795 112.728 1.00 72.11  0  114 MET B CE  1 
ATOM   6541 N  N   . SER B 2 115 ? 133.023 161.876 117.455 1.00 72.05  0  115 SER B N   1 
ATOM   6542 C  CA  . SER B 2 115 ? 132.167 161.159 118.394 1.00 72.05  0  115 SER B CA  1 
ATOM   6543 C  C   . SER B 2 115 ? 131.447 159.994 117.729 1.00 72.05  0  115 SER B C   1 
ATOM   6544 O  O   . SER B 2 115 ? 131.095 159.020 118.404 1.00 72.05  0  115 SER B O   1 
ATOM   6545 C  CB  . SER B 2 115 ? 131.157 162.120 119.020 1.00 72.05  0  115 SER B CB  1 
ATOM   6546 O  OG  . SER B 2 115 ? 131.811 163.129 119.768 1.00 72.05  0  115 SER B OG  1 
ATOM   6547 N  N   . LYS B 2 116 ? 131.213 160.077 116.417 1.00 73.10  0  116 LYS B N   1 
ATOM   6548 C  CA  . LYS B 2 116 ? 130.517 159.000 115.719 1.00 73.10  0  116 LYS B CA  1 
ATOM   6549 C  C   . LYS B 2 116 ? 131.326 157.708 115.741 1.00 73.10  0  116 LYS B C   1 
ATOM   6550 O  O   . LYS B 2 116 ? 130.768 156.621 115.930 1.00 73.10  0  116 LYS B O   1 
ATOM   6551 C  CB  . LYS B 2 116 ? 130.212 159.420 114.282 1.00 73.10  0  116 LYS B CB  1 
ATOM   6552 C  CG  . LYS B 2 116 ? 129.194 160.543 114.173 1.00 73.10  0  116 LYS B CG  1 
ATOM   6553 C  CD  . LYS B 2 116 ? 127.879 160.163 114.835 1.00 73.10  0  116 LYS B CD  1 
ATOM   6554 C  CE  . LYS B 2 116 ? 126.700 160.825 114.142 1.00 73.10  0  116 LYS B CE  1 
ATOM   6555 N  NZ  . LYS B 2 116 ? 126.414 160.208 112.818 1.00 73.10  1  116 LYS B NZ  1 
ATOM   6556 N  N   . ILE B 2 117 ? 132.638 157.805 115.549 1.00 70.28  0  117 ILE B N   1 
ATOM   6557 C  CA  . ILE B 2 117 ? 133.520 156.644 115.513 1.00 70.28  0  117 ILE B CA  1 
ATOM   6558 C  C   . ILE B 2 117 ? 134.129 156.459 116.895 1.00 70.28  0  117 ILE B C   1 
ATOM   6559 O  O   . ILE B 2 117 ? 134.747 157.382 117.440 1.00 70.28  0  117 ILE B O   1 
ATOM   6560 C  CB  . ILE B 2 117 ? 134.614 156.802 114.446 1.00 70.28  0  117 ILE B CB  1 
ATOM   6561 C  CG1 . ILE B 2 117 ? 133.991 156.893 113.053 1.00 70.28  0  117 ILE B CG1 1 
ATOM   6562 C  CG2 . ILE B 2 117 ? 135.594 155.644 114.521 1.00 70.28  0  117 ILE B CG2 1 
ATOM   6563 C  CD1 . ILE B 2 117 ? 134.985 156.732 111.923 1.00 70.28  0  117 ILE B CD1 1 
ATOM   6564 N  N   . SER B 2 118 ? 133.961 155.268 117.461 1.00 71.22  0  118 SER B N   1 
ATOM   6565 C  CA  . SER B 2 118 ? 134.513 154.922 118.761 1.00 71.22  0  118 SER B CA  1 
ATOM   6566 C  C   . SER B 2 118 ? 135.300 153.623 118.635 1.00 71.22  0  118 SER B C   1 
ATOM   6567 O  O   . SER B 2 118 ? 135.331 152.990 117.575 1.00 71.22  0  118 SER B O   1 
ATOM   6568 C  CB  . SER B 2 118 ? 133.408 154.797 119.818 1.00 71.22  0  118 SER B CB  1 
ATOM   6569 O  OG  . SER B 2 118 ? 132.556 153.700 119.536 1.00 71.22  0  118 SER B OG  1 
ATOM   6570 N  N   . LEU B 2 119 ? 135.945 153.225 119.732 1.00 71.84  0  119 LEU B N   1 
ATOM   6571 C  CA  . LEU B 2 119 ? 136.704 151.981 119.750 1.00 71.84  0  119 LEU B CA  1 
ATOM   6572 C  C   . LEU B 2 119 ? 135.818 150.749 119.634 1.00 71.84  0  119 LEU B C   1 
ATOM   6573 O  O   . LEU B 2 119 ? 136.336 149.657 119.377 1.00 71.84  0  119 LEU B O   1 
ATOM   6574 C  CB  . LEU B 2 119 ? 137.542 151.897 121.026 1.00 71.84  0  119 LEU B CB  1 
ATOM   6575 C  CG  . LEU B 2 119 ? 138.822 151.065 120.948 1.00 71.84  0  119 LEU B CG  1 
ATOM   6576 C  CD1 . LEU B 2 119 ? 139.751 151.611 119.876 1.00 71.84  0  119 LEU B CD1 1 
ATOM   6577 C  CD2 . LEU B 2 119 ? 139.521 151.026 122.297 1.00 71.84  0  119 LEU B CD2 1 
ATOM   6578 N  N   . ASN B 2 120 ? 134.506 150.895 119.811 1.00 73.94  0  120 ASN B N   1 
ATOM   6579 C  CA  . ASN B 2 120 ? 133.566 149.789 119.700 1.00 73.94  0  120 ASN B CA  1 
ATOM   6580 C  C   . ASN B 2 120 ? 132.889 149.733 118.337 1.00 73.94  0  120 ASN B C   1 
ATOM   6581 O  O   . ASN B 2 120 ? 131.912 148.996 118.171 1.00 73.94  0  120 ASN B O   1 
ATOM   6582 C  CB  . ASN B 2 120 ? 132.511 149.882 120.803 1.00 73.94  0  120 ASN B CB  1 
ATOM   6583 C  CG  . ASN B 2 120 ? 133.119 149.886 122.191 1.00 73.94  0  120 ASN B CG  1 
ATOM   6584 O  OD1 . ASN B 2 120 ? 134.076 149.162 122.463 1.00 73.94  0  120 ASN B OD1 1 
ATOM   6585 N  ND2 . ASN B 2 120 ? 132.566 150.704 123.078 1.00 73.94  0  120 ASN B ND2 1 
ATOM   6586 N  N   . THR B 2 121 ? 133.377 150.496 117.367 1.00 75.20  0  121 THR B N   1 
ATOM   6587 C  CA  . THR B 2 121 ? 132.800 150.461 116.030 1.00 75.20  0  121 THR B CA  1 
ATOM   6588 C  C   . THR B 2 121 ? 133.062 149.101 115.393 1.00 75.20  0  121 THR B C   1 
ATOM   6589 O  O   . THR B 2 121 ? 134.217 148.664 115.331 1.00 75.20  0  121 THR B O   1 
ATOM   6590 C  CB  . THR B 2 121 ? 133.388 151.572 115.162 1.00 75.20  0  121 THR B CB  1 
ATOM   6591 O  OG1 . THR B 2 121 ? 133.433 152.793 115.911 1.00 75.20  0  121 THR B OG1 1 
ATOM   6592 C  CG2 . THR B 2 121 ? 132.543 151.779 113.916 1.00 75.20  0  121 THR B CG2 1 
ATOM   6593 N  N   . PRO B 2 122 ? 132.033 148.407 114.917 1.00 77.66  0  122 PRO B N   1 
ATOM   6594 C  CA  . PRO B 2 122 ? 132.237 147.079 114.335 1.00 77.66  0  122 PRO B CA  1 
ATOM   6595 C  C   . PRO B 2 122 ? 132.948 147.170 112.998 1.00 77.66  0  122 PRO B C   1 
ATOM   6596 O  O   . PRO B 2 122 ? 132.613 148.024 112.164 1.00 77.66  0  122 PRO B O   1 
ATOM   6597 C  CB  . PRO B 2 122 ? 130.808 146.542 114.173 1.00 77.66  0  122 PRO B CB  1 
ATOM   6598 C  CG  . PRO B 2 122 ? 129.967 147.764 114.039 1.00 77.66  0  122 PRO B CG  1 
ATOM   6599 C  CD  . PRO B 2 122 ? 130.615 148.807 114.907 1.00 77.66  0  122 PRO B CD  1 
ATOM   6600 N  N   . PRO B 2 123 ? 133.949 146.321 112.767 1.00 76.78  0  123 PRO B N   1 
ATOM   6601 C  CA  . PRO B 2 123 ? 134.578 146.270 111.444 1.00 76.78  0  123 PRO B CA  1 
ATOM   6602 C  C   . PRO B 2 123 ? 133.554 145.967 110.362 1.00 76.78  0  123 PRO B C   1 
ATOM   6603 O  O   . PRO B 2 123 ? 132.622 145.185 110.562 1.00 76.78  0  123 PRO B O   1 
ATOM   6604 C  CB  . PRO B 2 123 ? 135.603 145.141 111.583 1.00 76.78  0  123 PRO B CB  1 
ATOM   6605 C  CG  . PRO B 2 123 ? 135.945 145.126 113.029 1.00 76.78  0  123 PRO B CG  1 
ATOM   6606 C  CD  . PRO B 2 123 ? 134.736 145.609 113.787 1.00 76.78  0  123 PRO B CD  1 
ATOM   6607 N  N   . GLY B 2 124 ? 133.739 146.596 109.207 1.00 75.45  0  124 GLY B N   1 
ATOM   6608 C  CA  . GLY B 2 124 ? 132.751 146.588 108.154 1.00 75.45  0  124 GLY B CA  1 
ATOM   6609 C  C   . GLY B 2 124 ? 131.852 147.804 108.143 1.00 75.45  0  124 GLY B C   1 
ATOM   6610 O  O   . GLY B 2 124 ? 131.098 147.988 107.180 1.00 75.45  0  124 GLY B O   1 
ATOM   6611 N  N   . THR B 2 125 ? 131.907 148.629 109.188 1.00 75.53  0  125 THR B N   1 
ATOM   6612 C  CA  . THR B 2 125 ? 131.157 149.876 109.208 1.00 75.53  0  125 THR B CA  1 
ATOM   6613 C  C   . THR B 2 125 ? 131.605 150.773 108.063 1.00 75.53  0  125 THR B C   1 
ATOM   6614 O  O   . THR B 2 125 ? 132.803 150.989 107.859 1.00 75.53  0  125 THR B O   1 
ATOM   6615 C  CB  . THR B 2 125 ? 131.354 150.586 110.548 1.00 75.53  0  125 THR B CB  1 
ATOM   6616 O  OG1 . THR B 2 125 ? 130.655 149.876 111.578 1.00 75.53  0  125 THR B OG1 1 
ATOM   6617 C  CG2 . THR B 2 125 ? 130.850 152.020 110.485 1.00 75.53  0  125 THR B CG2 1 
ATOM   6618 N  N   . LYS B 2 126 ? 130.640 151.295 107.315 1.00 76.85  0  126 LYS B N   1 
ATOM   6619 C  CA  . LYS B 2 126 ? 130.936 152.116 106.154 1.00 76.85  0  126 LYS B CA  1 
ATOM   6620 C  C   . LYS B 2 126 ? 131.098 153.574 106.557 1.00 76.85  0  126 LYS B C   1 
ATOM   6621 O  O   . LYS B 2 126 ? 130.324 154.105 107.359 1.00 76.85  0  126 LYS B O   1 
ATOM   6622 C  CB  . LYS B 2 126 ? 129.836 151.975 105.103 1.00 76.85  0  126 LYS B CB  1 
ATOM   6623 C  CG  . LYS B 2 126 ? 129.428 150.535 104.843 1.00 76.85  0  126 LYS B CG  1 
ATOM   6624 C  CD  . LYS B 2 126 ? 130.293 149.908 103.763 1.00 76.85  0  126 LYS B CD  1 
ATOM   6625 C  CE  . LYS B 2 126 ? 130.040 148.415 103.649 1.00 76.85  0  126 LYS B CE  1 
ATOM   6626 N  NZ  . LYS B 2 126 ? 130.287 147.711 104.936 1.00 76.85  1  126 LYS B NZ  1 
ATOM   6627 N  N   . VAL B 2 127 ? 132.116 154.216 105.994 1.00 72.01  0  127 VAL B N   1 
ATOM   6628 C  CA  . VAL B 2 127 ? 132.414 155.618 106.249 1.00 72.01  0  127 VAL B CA  1 
ATOM   6629 C  C   . VAL B 2 127 ? 132.480 156.338 104.911 1.00 72.01  0  127 VAL B C   1 
ATOM   6630 O  O   . VAL B 2 127 ? 133.183 155.896 103.995 1.00 72.01  0  127 VAL B O   1 
ATOM   6631 C  CB  . VAL B 2 127 ? 133.733 155.794 107.025 1.00 72.01  0  127 VAL B CB  1 
ATOM   6632 C  CG1 . VAL B 2 127 ? 134.119 157.262 107.095 1.00 72.01  0  127 VAL B CG1 1 
ATOM   6633 C  CG2 . VAL B 2 127 ? 133.611 155.202 108.420 1.00 72.01  0  127 VAL B CG2 1 
ATOM   6634 N  N   . LYS B 2 128 ? 131.744 157.437 104.797 1.00 71.48  0  128 LYS B N   1 
ATOM   6635 C  CA  . LYS B 2 128 ? 131.725 158.256 103.595 1.00 71.48  0  128 LYS B CA  1 
ATOM   6636 C  C   . LYS B 2 128 ? 132.555 159.510 103.826 1.00 71.48  0  128 LYS B C   1 
ATOM   6637 O  O   . LYS B 2 128 ? 132.337 160.234 104.805 1.00 71.48  0  128 LYS B O   1 
ATOM   6638 C  CB  . LYS B 2 128 ? 130.294 158.632 103.210 1.00 71.48  0  128 LYS B CB  1 
ATOM   6639 C  CG  . LYS B 2 128 ? 130.187 159.427 101.920 1.00 71.48  0  128 LYS B CG  1 
ATOM   6640 C  CD  . LYS B 2 128 ? 128.743 159.784 101.610 1.00 71.48  0  128 LYS B CD  1 
ATOM   6641 C  CE  . LYS B 2 128 ? 128.606 161.255 101.251 1.00 71.48  0  128 LYS B CE  1 
ATOM   6642 N  NZ  . LYS B 2 128 ? 127.184 161.696 101.244 1.00 71.48  1  128 LYS B NZ  1 
ATOM   6643 N  N   . LEU B 2 129 ? 133.509 159.749 102.931 1.00 70.76  0  129 LEU B N   1 
ATOM   6644 C  CA  . LEU B 2 129 ? 134.337 160.945 102.943 1.00 70.76  0  129 LEU B CA  1 
ATOM   6645 C  C   . LEU B 2 129 ? 133.840 161.894 101.862 1.00 70.76  0  129 LEU B C   1 
ATOM   6646 O  O   . LEU B 2 129 ? 133.726 161.507 100.693 1.00 70.76  0  129 LEU B O   1 
ATOM   6647 C  CB  . LEU B 2 129 ? 135.807 160.595 102.710 1.00 70.76  0  129 LEU B CB  1 
ATOM   6648 C  CG  . LEU B 2 129 ? 136.362 159.380 103.457 1.00 70.76  0  129 LEU B CG  1 
ATOM   6649 C  CD1 . LEU B 2 129 ? 137.844 159.209 103.168 1.00 70.76  0  129 LEU B CD1 1 
ATOM   6650 C  CD2 . LEU B 2 129 ? 136.124 159.510 104.951 1.00 70.76  0  129 LEU B CD2 1 
ATOM   6651 N  N   . SER B 2 130 ? 133.544 163.130 102.254 1.00 71.31  0  130 SER B N   1 
ATOM   6652 C  CA  . SER B 2 130 ? 132.948 164.115 101.368 1.00 71.31  0  130 SER B CA  1 
ATOM   6653 C  C   . SER B 2 130 ? 133.840 165.345 101.272 1.00 71.31  0  130 SER B C   1 
ATOM   6654 O  O   . SER B 2 130 ? 134.744 165.551 102.086 1.00 71.31  0  130 SER B O   1 
ATOM   6655 C  CB  . SER B 2 130 ? 131.549 164.521 101.852 1.00 71.31  0  130 SER B CB  1 
ATOM   6656 O  OG  . SER B 2 130 ? 131.614 165.177 103.106 1.00 71.31  0  130 SER B OG  1 
ATOM   6657 N  N   . GLY B 2 131 ? 133.568 166.164 100.262 1.00 72.36  0  131 GLY B N   1 
ATOM   6658 C  CA  . GLY B 2 131 ? 134.365 167.362 100.058 1.00 72.36  0  131 GLY B CA  1 
ATOM   6659 C  C   . GLY B 2 131 ? 135.782 167.005 99.660  1.00 72.36  0  131 GLY B C   1 
ATOM   6660 O  O   . GLY B 2 131 ? 136.011 166.188 98.761  1.00 72.36  0  131 GLY B O   1 
ATOM   6661 N  N   . ILE B 2 132 ? 136.750 167.620 100.332 1.00 69.76  0  132 ILE B N   1 
ATOM   6662 C  CA  . ILE B 2 132 ? 138.165 167.385 100.077 1.00 69.76  0  132 ILE B CA  1 
ATOM   6663 C  C   . ILE B 2 132 ? 138.793 166.847 101.354 1.00 69.76  0  132 ILE B C   1 
ATOM   6664 O  O   . ILE B 2 132 ? 138.669 167.462 102.419 1.00 69.76  0  132 ILE B O   1 
ATOM   6665 C  CB  . ILE B 2 132 ? 138.880 168.667 99.615  1.00 69.76  0  132 ILE B CB  1 
ATOM   6666 C  CG1 . ILE B 2 132 ? 138.232 169.205 98.338  1.00 69.76  0  132 ILE B CG1 1 
ATOM   6667 C  CG2 . ILE B 2 132 ? 140.360 168.401 99.391  1.00 69.76  0  132 ILE B CG2 1 
ATOM   6668 C  CD1 . ILE B 2 132 ? 138.297 168.250 97.172  1.00 69.76  0  132 ILE B CD1 1 
ATOM   6669 N  N   . VAL B 2 133 ? 139.463 165.703 101.246 1.00 69.22  0  133 VAL B N   1 
ATOM   6670 C  CA  . VAL B 2 133 ? 140.136 165.070 102.372 1.00 69.22  0  133 VAL B CA  1 
ATOM   6671 C  C   . VAL B 2 133 ? 141.620 164.990 102.047 1.00 69.22  0  133 VAL B C   1 
ATOM   6672 O  O   . VAL B 2 133 ? 142.002 164.653 100.920 1.00 69.22  0  133 VAL B O   1 
ATOM   6673 C  CB  . VAL B 2 133 ? 139.556 163.673 102.674 1.00 69.22  0  133 VAL B CB  1 
ATOM   6674 C  CG1 . VAL B 2 133 ? 140.238 163.070 103.885 1.00 69.22  0  133 VAL B CG1 1 
ATOM   6675 C  CG2 . VAL B 2 133 ? 138.052 163.756 102.887 1.00 69.22  0  133 VAL B CG2 1 
ATOM   6676 N  N   . ASP B 2 134 ? 142.456 165.310 103.031 1.00 69.79  0  134 ASP B N   1 
ATOM   6677 C  CA  . ASP B 2 134 ? 143.879 165.523 102.805 1.00 69.79  0  134 ASP B CA  1 
ATOM   6678 C  C   . ASP B 2 134 ? 144.704 164.332 103.286 1.00 69.79  0  134 ASP B C   1 
ATOM   6679 O  O   . ASP B 2 134 ? 144.622 163.932 104.456 1.00 69.79  0  134 ASP B O   1 
ATOM   6680 C  CB  . ASP B 2 134 ? 144.333 166.819 103.479 1.00 69.79  0  134 ASP B CB  1 
ATOM   6681 C  CG  . ASP B 2 134 ? 143.859 166.932 104.913 1.00 69.79  0  134 ASP B CG  1 
ATOM   6682 O  OD1 . ASP B 2 134 ? 143.086 166.060 105.361 1.00 69.79  0  134 ASP B OD1 1 
ATOM   6683 O  OD2 . ASP B 2 134 ? 144.247 167.909 105.587 1.00 69.79  -1 134 ASP B OD2 1 
ATOM   6684 N  N   . ILE B 2 135 ? 145.496 163.776 102.368 1.00 69.16  0  135 ILE B N   1 
ATOM   6685 C  CA  . ILE B 2 135 ? 146.522 162.779 102.646 1.00 69.16  0  135 ILE B CA  1 
ATOM   6686 C  C   . ILE B 2 135 ? 147.819 163.512 102.944 1.00 69.16  0  135 ILE B C   1 
ATOM   6687 O  O   . ILE B 2 135 ? 148.149 164.495 102.269 1.00 69.16  0  135 ILE B O   1 
ATOM   6688 C  CB  . ILE B 2 135 ? 146.709 161.832 101.442 1.00 69.16  0  135 ILE B CB  1 
ATOM   6689 C  CG1 . ILE B 2 135 ? 145.454 161.007 101.160 1.00 69.16  0  135 ILE B CG1 1 
ATOM   6690 C  CG2 . ILE B 2 135 ? 147.911 160.928 101.639 1.00 69.16  0  135 ILE B CG2 1 
ATOM   6691 C  CD1 . ILE B 2 135 ? 144.509 161.646 100.166 1.00 69.16  0  135 ILE B CD1 1 
ATOM   6692 N  N   . LYS B 2 136 ? 148.569 163.053 103.945 1.00 68.64  0  136 LYS B N   1 
ATOM   6693 C  CA  . LYS B 2 136 ? 149.928 163.560 104.081 1.00 68.64  0  136 LYS B CA  1 
ATOM   6694 C  C   . LYS B 2 136 ? 150.797 162.534 104.790 1.00 68.64  0  136 LYS B C   1 
ATOM   6695 O  O   . LYS B 2 136 ? 150.403 161.975 105.818 1.00 68.64  0  136 LYS B O   1 
ATOM   6696 C  CB  . LYS B 2 136 ? 149.970 164.910 104.809 1.00 68.64  0  136 LYS B CB  1 
ATOM   6697 C  CG  . LYS B 2 136 ? 149.513 164.899 106.247 1.00 68.64  0  136 LYS B CG  1 
ATOM   6698 C  CD  . LYS B 2 136 ? 150.205 166.009 107.017 1.00 68.64  0  136 LYS B CD  1 
ATOM   6699 C  CE  . LYS B 2 136 ? 150.079 167.345 106.301 1.00 68.64  0  136 LYS B CE  1 
ATOM   6700 N  NZ  . LYS B 2 136 ? 148.702 167.900 106.394 1.00 68.64  1  136 LYS B NZ  1 
ATOM   6701 N  N   . ASN B 2 137 ? 151.980 162.297 104.221 1.00 68.46  0  137 ASN B N   1 
ATOM   6702 C  CA  . ASN B 2 137 ? 152.927 161.305 104.725 1.00 68.46  0  137 ASN B CA  1 
ATOM   6703 C  C   . ASN B 2 137 ? 152.242 159.959 104.935 1.00 68.46  0  137 ASN B C   1 
ATOM   6704 O  O   . ASN B 2 137 ? 152.364 159.327 105.987 1.00 68.46  0  137 ASN B O   1 
ATOM   6705 C  CB  . ASN B 2 137 ? 153.596 161.787 106.013 1.00 68.46  0  137 ASN B CB  1 
ATOM   6706 C  CG  . ASN B 2 137 ? 154.783 162.689 105.749 1.00 68.46  0  137 ASN B CG  1 
ATOM   6707 O  OD1 . ASN B 2 137 ? 154.636 163.902 105.599 1.00 68.46  0  137 ASN B OD1 1 
ATOM   6708 N  ND2 . ASN B 2 137 ? 155.971 162.098 105.689 1.00 68.46  0  137 ASN B ND2 1 
ATOM   6709 N  N   . GLY B 2 138 ? 151.511 159.515 103.916 1.00 67.28  0  138 GLY B N   1 
ATOM   6710 C  CA  . GLY B 2 138 ? 150.744 158.303 104.090 1.00 67.28  0  138 GLY B CA  1 
ATOM   6711 C  C   . GLY B 2 138 ? 149.316 158.573 104.511 1.00 67.28  0  138 GLY B C   1 
ATOM   6712 O  O   . GLY B 2 138 ? 148.419 158.712 103.676 1.00 67.28  0  138 GLY B O   1 
ATOM   6713 N  N   . PHE B 2 139 ? 149.100 158.596 105.822 1.00 67.28  0  139 PHE B N   1 
ATOM   6714 C  CA  . PHE B 2 139 ? 147.761 158.604 106.392 1.00 67.28  0  139 PHE B CA  1 
ATOM   6715 C  C   . PHE B 2 139 ? 146.924 159.795 105.930 1.00 67.28  0  139 PHE B C   1 
ATOM   6716 O  O   . PHE B 2 139 ? 147.439 160.885 105.648 1.00 67.28  0  139 PHE B O   1 
ATOM   6717 C  CB  . PHE B 2 139 ? 147.865 158.592 107.917 1.00 67.28  0  139 PHE B CB  1 
ATOM   6718 C  CG  . PHE B 2 139 ? 148.856 157.593 108.442 1.00 67.28  0  139 PHE B CG  1 
ATOM   6719 C  CD1 . PHE B 2 139 ? 148.790 156.268 108.054 1.00 67.28  0  139 PHE B CD1 1 
ATOM   6720 C  CD2 . PHE B 2 139 ? 149.856 157.977 109.313 1.00 67.28  0  139 PHE B CD2 1 
ATOM   6721 C  CE1 . PHE B 2 139 ? 149.697 155.343 108.530 1.00 67.28  0  139 PHE B CE1 1 
ATOM   6722 C  CE2 . PHE B 2 139 ? 150.768 157.059 109.791 1.00 67.28  0  139 PHE B CE2 1 
ATOM   6723 C  CZ  . PHE B 2 139 ? 150.687 155.740 109.401 1.00 67.28  0  139 PHE B CZ  1 
ATOM   6724 N  N   . LEU B 2 140 ? 145.623 159.539 105.812 1.00 67.28  0  140 LEU B N   1 
ATOM   6725 C  CA  . LEU B 2 140 ? 144.592 160.557 105.682 1.00 67.28  0  140 LEU B CA  1 
ATOM   6726 C  C   . LEU B 2 140 ? 144.406 161.298 107.003 1.00 67.28  0  140 LEU B C   1 
ATOM   6727 O  O   . LEU B 2 140 ? 144.744 160.797 108.077 1.00 67.28  0  140 LEU B O   1 
ATOM   6728 C  CB  . LEU B 2 140 ? 143.260 159.914 105.291 1.00 67.28  0  140 LEU B CB  1 
ATOM   6729 C  CG  . LEU B 2 140 ? 142.970 159.430 103.874 1.00 67.28  0  140 LEU B CG  1 
ATOM   6730 C  CD1 . LEU B 2 140 ? 141.812 158.455 103.894 1.00 67.28  0  140 LEU B CD1 1 
ATOM   6731 C  CD2 . LEU B 2 140 ? 142.607 160.611 103.020 1.00 67.28  0  140 LEU B CD2 1 
ATOM   6732 N  N   . LEU B 2 141 ? 143.837 162.499 106.920 1.00 67.38  0  141 LEU B N   1 
ATOM   6733 C  CA  . LEU B 2 141 ? 143.367 163.217 108.101 1.00 67.38  0  141 LEU B CA  1 
ATOM   6734 C  C   . LEU B 2 141 ? 141.845 163.266 108.073 1.00 67.38  0  141 LEU B C   1 
ATOM   6735 O  O   . LEU B 2 141 ? 141.258 163.759 107.104 1.00 67.38  0  141 LEU B O   1 
ATOM   6736 C  CB  . LEU B 2 141 ? 143.954 164.626 108.169 1.00 67.38  0  141 LEU B CB  1 
ATOM   6737 C  CG  . LEU B 2 141 ? 145.464 164.740 107.971 1.00 67.38  0  141 LEU B CG  1 
ATOM   6738 C  CD1 . LEU B 2 141 ? 145.868 166.164 107.648 1.00 67.38  0  141 LEU B CD1 1 
ATOM   6739 C  CD2 . LEU B 2 141 ? 146.163 164.274 109.226 1.00 67.38  0  141 LEU B CD2 1 
ATOM   6740 N  N   . LEU B 2 142 ? 141.209 162.763 109.132 1.00 67.84  0  142 LEU B N   1 
ATOM   6741 C  CA  . LEU B 2 142 ? 139.756 162.678 109.194 1.00 67.84  0  142 LEU B CA  1 
ATOM   6742 C  C   . LEU B 2 142 ? 139.222 163.476 110.375 1.00 67.84  0  142 LEU B C   1 
ATOM   6743 O  O   . LEU B 2 142 ? 139.830 163.499 111.450 1.00 67.84  0  142 LEU B O   1 
ATOM   6744 C  CB  . LEU B 2 142 ? 139.293 161.222 109.305 1.00 67.84  0  142 LEU B CB  1 
ATOM   6745 C  CG  . LEU B 2 142 ? 139.485 160.345 108.066 1.00 67.84  0  142 LEU B CG  1 
ATOM   6746 C  CD1 . LEU B 2 142 ? 138.611 159.105 108.142 1.00 67.84  0  142 LEU B CD1 1 
ATOM   6747 C  CD2 . LEU B 2 142 ? 139.198 161.126 106.795 1.00 67.84  0  142 LEU B CD2 1 
ATOM   6748 N  N   . ASN B 2 143 ? 138.080 164.127 110.167 1.00 70.21  0  143 ASN B N   1 
ATOM   6749 C  CA  . ASN B 2 143 ? 137.385 164.853 111.222 1.00 70.21  0  143 ASN B CA  1 
ATOM   6750 C  C   . ASN B 2 143 ? 135.890 164.812 110.924 1.00 70.21  0  143 ASN B C   1 
ATOM   6751 O  O   . ASN B 2 143 ? 135.440 164.113 110.011 1.00 70.21  0  143 ASN B O   1 
ATOM   6752 C  CB  . ASN B 2 143 ? 137.919 166.286 111.344 1.00 70.21  0  143 ASN B CB  1 
ATOM   6753 C  CG  . ASN B 2 143 ? 138.023 166.987 110.005 1.00 70.21  0  143 ASN B CG  1 
ATOM   6754 O  OD1 . ASN B 2 143 ? 137.638 166.441 108.973 1.00 70.21  0  143 ASN B OD1 1 
ATOM   6755 N  ND2 . ASN B 2 143 ? 138.546 168.207 110.016 1.00 70.21  0  143 ASN B ND2 1 
ATOM   6756 N  N   . ASP B 2 144 ? 135.112 165.568 111.702 1.00 71.50  0  144 ASP B N   1 
ATOM   6757 C  CA  . ASP B 2 144 ? 133.663 165.567 111.538 1.00 71.50  0  144 ASP B CA  1 
ATOM   6758 C  C   . ASP B 2 144 ? 133.213 166.282 110.272 1.00 71.50  0  144 ASP B C   1 
ATOM   6759 O  O   . ASP B 2 144 ? 132.091 166.049 109.810 1.00 71.50  0  144 ASP B O   1 
ATOM   6760 C  CB  . ASP B 2 144 ? 132.995 166.211 112.754 1.00 71.50  0  144 ASP B CB  1 
ATOM   6761 C  CG  . ASP B 2 144 ? 133.130 165.372 114.007 1.00 71.50  0  144 ASP B CG  1 
ATOM   6762 O  OD1 . ASP B 2 144 ? 133.215 164.132 113.889 1.00 71.50  0  144 ASP B OD1 1 
ATOM   6763 O  OD2 . ASP B 2 144 ? 133.148 165.954 115.112 1.00 71.50  -1 144 ASP B OD2 1 
ATOM   6764 N  N   . SER B 2 145 ? 134.055 167.145 109.701 1.00 70.80  0  145 SER B N   1 
ATOM   6765 C  CA  . SER B 2 145 ? 133.635 167.955 108.565 1.00 70.80  0  145 SER B CA  1 
ATOM   6766 C  C   . SER B 2 145 ? 133.513 167.152 107.277 1.00 70.80  0  145 SER B C   1 
ATOM   6767 O  O   . SER B 2 145 ? 132.878 167.625 106.329 1.00 70.80  0  145 SER B O   1 
ATOM   6768 C  CB  . SER B 2 145 ? 134.610 169.115 108.360 1.00 70.80  0  145 SER B CB  1 
ATOM   6769 O  OG  . SER B 2 145 ? 135.903 168.642 108.023 1.00 70.80  0  145 SER B OG  1 
ATOM   6770 N  N   . ASN B 2 146 ? 134.101 165.956 107.214 1.00 71.28  0  146 ASN B N   1 
ATOM   6771 C  CA  . ASN B 2 146 ? 134.094 165.176 105.985 1.00 71.28  0  146 ASN B CA  1 
ATOM   6772 C  C   . ASN B 2 146 ? 133.742 163.706 106.162 1.00 71.28  0  146 ASN B C   1 
ATOM   6773 O  O   . ASN B 2 146 ? 133.516 163.029 105.153 1.00 71.28  0  146 ASN B O   1 
ATOM   6774 C  CB  . ASN B 2 146 ? 135.459 165.273 105.284 1.00 71.28  0  146 ASN B CB  1 
ATOM   6775 C  CG  . ASN B 2 146 ? 136.619 165.068 106.237 1.00 71.28  0  146 ASN B CG  1 
ATOM   6776 O  OD1 . ASN B 2 146 ? 136.456 164.509 107.320 1.00 71.28  0  146 ASN B OD1 1 
ATOM   6777 N  ND2 . ASN B 2 146 ? 137.800 165.523 105.836 1.00 71.28  0  146 ASN B ND2 1 
ATOM   6778 N  N   . THR B 2 147 ? 133.674 163.191 107.386 1.00 72.31  0  147 THR B N   1 
ATOM   6779 C  CA  . THR B 2 147 ? 133.417 161.777 107.628 1.00 72.31  0  147 THR B CA  1 
ATOM   6780 C  C   . THR B 2 147 ? 131.997 161.585 108.140 1.00 72.31  0  147 THR B C   1 
ATOM   6781 O  O   . THR B 2 147 ? 131.579 162.252 109.092 1.00 72.31  0  147 THR B O   1 
ATOM   6782 C  CB  . THR B 2 147 ? 134.413 161.200 108.636 1.00 72.31  0  147 THR B CB  1 
ATOM   6783 O  OG1 . THR B 2 147 ? 134.214 161.815 109.915 1.00 72.31  0  147 THR B OG1 1 
ATOM   6784 C  CG2 . THR B 2 147 ? 135.834 161.449 108.174 1.00 72.31  0  147 THR B CG2 1 
ATOM   6785 N  N   . THR B 2 148 ? 131.261 160.673 107.506 1.00 72.67  0  148 THR B N   1 
ATOM   6786 C  CA  . THR B 2 148 ? 129.920 160.305 107.946 1.00 72.67  0  148 THR B CA  1 
ATOM   6787 C  C   . THR B 2 148 ? 129.833 158.791 108.075 1.00 72.67  0  148 THR B C   1 
ATOM   6788 O  O   . THR B 2 148 ? 130.229 158.066 107.159 1.00 72.67  0  148 THR B O   1 
ATOM   6789 C  CB  . THR B 2 148 ? 128.850 160.816 106.973 1.00 72.67  0  148 THR B CB  1 
ATOM   6790 O  OG1 . THR B 2 148 ? 129.070 160.251 105.676 1.00 72.67  0  148 THR B OG1 1 
ATOM   6791 C  CG2 . THR B 2 148 ? 128.894 162.335 106.875 1.00 72.67  0  148 THR B CG2 1 
ATOM   6792 N  N   . VAL B 2 149 ? 129.313 158.318 109.204 1.00 71.83  0  149 VAL B N   1 
ATOM   6793 C  CA  . VAL B 2 149 ? 129.199 156.887 109.470 1.00 71.83  0  149 VAL B CA  1 
ATOM   6794 C  C   . VAL B 2 149 ? 127.853 156.411 108.935 1.00 71.83  0  149 VAL B C   1 
ATOM   6795 O  O   . VAL B 2 149 ? 126.799 156.801 109.444 1.00 71.83  0  149 VAL B O   1 
ATOM   6796 C  CB  . VAL B 2 149 ? 129.341 156.581 110.965 1.00 71.83  0  149 VAL B CB  1 
ATOM   6797 C  CG1 . VAL B 2 149 ? 128.926 155.147 111.257 1.00 71.83  0  149 VAL B CG1 1 
ATOM   6798 C  CG2 . VAL B 2 149 ? 130.766 156.830 111.422 1.00 71.83  0  149 VAL B CG2 1 
ATOM   6799 N  N   . LEU B 2 150 ? 127.885 155.572 107.904 1.00 73.81  0  150 LEU B N   1 
ATOM   6800 C  CA  . LEU B 2 150 ? 126.669 155.071 107.265 1.00 73.81  0  150 LEU B CA  1 
ATOM   6801 C  C   . LEU B 2 150 ? 126.297 153.692 107.810 1.00 73.81  0  150 LEU B C   1 
ATOM   6802 O  O   . LEU B 2 150 ? 126.182 152.711 107.075 1.00 73.81  0  150 LEU B O   1 
ATOM   6803 C  CB  . LEU B 2 150 ? 126.848 155.039 105.750 1.00 73.81  0  150 LEU B CB  1 
ATOM   6804 C  CG  . LEU B 2 150 ? 126.464 156.294 104.962 1.00 73.81  0  150 LEU B CG  1 
ATOM   6805 C  CD1 . LEU B 2 150 ? 127.351 157.472 105.331 1.00 73.81  0  150 LEU B CD1 1 
ATOM   6806 C  CD2 . LEU B 2 150 ? 126.525 156.025 103.467 1.00 73.81  0  150 LEU B CD2 1 
ATOM   6807 N  N   . GLY B 2 151 ? 126.104 153.629 109.125 1.00 77.99  0  151 GLY B N   1 
ATOM   6808 C  CA  . GLY B 2 151 ? 125.683 152.402 109.777 1.00 77.99  0  151 GLY B CA  1 
ATOM   6809 C  C   . GLY B 2 151 ? 126.653 151.248 109.627 1.00 77.99  0  151 GLY B C   1 
ATOM   6810 O  O   . GLY B 2 151 ? 127.771 151.297 110.147 1.00 77.99  0  151 GLY B O   1 
ATOM   6811 N  N   . GLY B 2 152 ? 126.233 150.199 108.925 1.00 85.04  0  152 GLY B N   1 
ATOM   6812 C  CA  . GLY B 2 152 ? 127.090 149.054 108.680 1.00 85.04  0  152 GLY B CA  1 
ATOM   6813 C  C   . GLY B 2 152 ? 126.797 147.862 109.568 1.00 85.04  0  152 GLY B C   1 
ATOM   6814 O  O   . GLY B 2 152 ? 126.912 147.948 110.795 1.00 85.04  0  152 GLY B O   1 
ATOM   6815 N  N   . GLU B 2 153 ? 126.417 146.738 108.955 1.00 91.47  0  153 GLU B N   1 
ATOM   6816 C  CA  . GLU B 2 153 ? 126.126 145.517 109.705 1.00 91.47  0  153 GLU B CA  1 
ATOM   6817 C  C   . GLU B 2 153 ? 126.317 144.336 108.752 1.00 91.47  0  153 GLU B C   1 
ATOM   6818 O  O   . GLU B 2 153 ? 125.430 144.047 107.945 1.00 91.47  0  153 GLU B O   1 
ATOM   6819 C  CB  . GLU B 2 153 ? 124.716 145.553 110.274 1.00 91.47  0  153 GLU B CB  1 
ATOM   6820 C  CG  . GLU B 2 153 ? 124.290 144.290 111.008 1.00 91.47  0  153 GLU B CG  1 
ATOM   6821 C  CD  . GLU B 2 153 ? 124.801 144.239 112.433 1.00 91.47  0  153 GLU B CD  1 
ATOM   6822 O  OE1 . GLU B 2 153 ? 125.073 145.313 113.009 1.00 91.47  0  153 GLU B OE1 1 
ATOM   6823 O  OE2 . GLU B 2 153 ? 124.926 143.123 112.980 1.00 91.47  -1 153 GLU B OE2 1 
ATOM   6824 N  N   . VAL B 2 154 ? 127.465 143.667 108.852 1.00 93.11  0  154 VAL B N   1 
ATOM   6825 C  CA  . VAL B 2 154 ? 127.764 142.505 108.020 1.00 93.11  0  154 VAL B CA  1 
ATOM   6826 C  C   . VAL B 2 154 ? 128.180 141.352 108.929 1.00 93.11  0  154 VAL B C   1 
ATOM   6827 O  O   . VAL B 2 154 ? 129.236 141.408 109.579 1.00 93.11  0  154 VAL B O   1 
ATOM   6828 C  CB  . VAL B 2 154 ? 128.847 142.801 106.970 1.00 93.11  0  154 VAL B CB  1 
ATOM   6829 C  CG1 . VAL B 2 154 ? 128.904 141.682 105.946 1.00 93.11  0  154 VAL B CG1 1 
ATOM   6830 C  CG2 . VAL B 2 154 ? 128.589 144.135 106.288 1.00 93.11  0  154 VAL B CG2 1 
ATOM   6831 N  N   . GLU B 2 155 ? 127.376 140.285 108.917 1.00 97.13  0  155 GLU B N   1 
ATOM   6832 C  CA  . GLU B 2 155 ? 127.391 139.301 109.995 1.00 97.13  0  155 GLU B CA  1 
ATOM   6833 C  C   . GLU B 2 155 ? 128.726 138.575 110.101 1.00 97.13  0  155 GLU B C   1 
ATOM   6834 O  O   . GLU B 2 155 ? 129.207 138.329 111.212 1.00 97.13  0  155 GLU B O   1 
ATOM   6835 C  CB  . GLU B 2 155 ? 126.250 138.303 109.799 1.00 97.13  0  155 GLU B CB  1 
ATOM   6836 C  CG  . GLU B 2 155 ? 126.178 137.698 108.405 1.00 97.13  0  155 GLU B CG  1 
ATOM   6837 C  CD  . GLU B 2 155 ? 125.021 136.732 108.247 1.00 97.13  0  155 GLU B CD  1 
ATOM   6838 O  OE1 . GLU B 2 155 ? 124.251 136.561 109.216 1.00 97.13  0  155 GLU B OE1 1 
ATOM   6839 O  OE2 . GLU B 2 155 ? 124.881 136.144 107.154 1.00 97.13  -1 155 GLU B OE2 1 
ATOM   6840 N  N   . HIS B 2 156 ? 129.337 138.209 108.971 1.00 96.58  0  156 HIS B N   1 
ATOM   6841 C  CA  . HIS B 2 156 ? 130.517 137.351 109.040 1.00 96.58  0  156 HIS B CA  1 
ATOM   6842 C  C   . HIS B 2 156 ? 131.688 138.068 109.705 1.00 96.58  0  156 HIS B C   1 
ATOM   6843 O  O   . HIS B 2 156 ? 132.320 137.526 110.621 1.00 96.58  0  156 HIS B O   1 
ATOM   6844 C  CB  . HIS B 2 156 ? 130.896 136.842 107.646 1.00 96.58  0  156 HIS B CB  1 
ATOM   6845 C  CG  . HIS B 2 156 ? 131.229 137.921 106.666 1.00 96.58  0  156 HIS B CG  1 
ATOM   6846 N  ND1 . HIS B 2 156 ? 132.510 138.402 106.495 1.00 96.58  0  156 HIS B ND1 1 
ATOM   6847 C  CD2 . HIS B 2 156 ? 130.453 138.600 105.789 1.00 96.58  0  156 HIS B CD2 1 
ATOM   6848 C  CE1 . HIS B 2 156 ? 132.506 139.337 105.563 1.00 96.58  0  156 HIS B CE1 1 
ATOM   6849 N  NE2 . HIS B 2 156 ? 131.270 139.477 105.119 1.00 96.58  0  156 HIS B NE2 1 
ATOM   6850 N  N   . LEU B 2 157 ? 131.979 139.303 109.295 1.00 94.04  0  157 LEU B N   1 
ATOM   6851 C  CA  . LEU B 2 157 ? 133.096 139.967 109.952 1.00 94.04  0  157 LEU B CA  1 
ATOM   6852 C  C   . LEU B 2 157 ? 132.713 140.625 111.272 1.00 94.04  0  157 LEU B C   1 
ATOM   6853 O  O   . LEU B 2 157 ? 133.610 140.914 112.063 1.00 94.04  0  157 LEU B O   1 
ATOM   6854 C  CB  . LEU B 2 157 ? 133.778 140.993 109.037 1.00 94.04  0  157 LEU B CB  1 
ATOM   6855 C  CG  . LEU B 2 157 ? 133.158 142.333 108.667 1.00 94.04  0  157 LEU B CG  1 
ATOM   6856 C  CD1 . LEU B 2 157 ? 134.228 143.236 108.085 1.00 94.04  0  157 LEU B CD1 1 
ATOM   6857 C  CD2 . LEU B 2 157 ? 132.100 142.101 107.642 1.00 94.04  0  157 LEU B CD2 1 
ATOM   6858 N  N   . ILE B 2 158 ? 131.425 140.821 111.578 1.00 94.11  0  158 ILE B N   1 
ATOM   6859 C  CA  . ILE B 2 158 ? 131.102 141.149 112.968 1.00 94.11  0  158 ILE B CA  1 
ATOM   6860 C  C   . ILE B 2 158 ? 131.351 139.947 113.877 1.00 94.11  0  158 ILE B C   1 
ATOM   6861 O  O   . ILE B 2 158 ? 131.864 140.088 114.996 1.00 94.11  0  158 ILE B O   1 
ATOM   6862 C  CB  . ILE B 2 158 ? 129.665 141.686 113.099 1.00 94.11  0  158 ILE B CB  1 
ATOM   6863 C  CG1 . ILE B 2 158 ? 129.457 142.873 112.159 1.00 94.11  0  158 ILE B CG1 1 
ATOM   6864 C  CG2 . ILE B 2 158 ? 129.372 142.083 114.538 1.00 94.11  0  158 ILE B CG2 1 
ATOM   6865 C  CD1 . ILE B 2 158 ? 128.137 143.576 112.341 1.00 94.11  0  158 ILE B CD1 1 
ATOM   6866 N  N   . GLU B 2 159 ? 131.012 138.743 113.411 1.00 98.99  0  159 GLU B N   1 
ATOM   6867 C  CA  . GLU B 2 159 ? 131.340 137.542 114.172 1.00 98.99  0  159 GLU B CA  1 
ATOM   6868 C  C   . GLU B 2 159 ? 132.849 137.369 114.294 1.00 98.99  0  159 GLU B C   1 
ATOM   6869 O  O   . GLU B 2 159 ? 133.347 136.883 115.316 1.00 98.99  0  159 GLU B O   1 
ATOM   6870 C  CB  . GLU B 2 159 ? 130.705 136.316 113.517 1.00 98.99  0  159 GLU B CB  1 
ATOM   6871 C  CG  . GLU B 2 159 ? 129.205 136.209 113.732 1.00 98.99  0  159 GLU B CG  1 
ATOM   6872 C  CD  . GLU B 2 159 ? 128.496 135.536 112.573 1.00 98.99  0  159 GLU B CD  1 
ATOM   6873 O  OE1 . GLU B 2 159 ? 129.175 134.868 111.766 1.00 98.99  0  159 GLU B OE1 1 
ATOM   6874 O  OE2 . GLU B 2 159 ? 127.259 135.678 112.468 1.00 98.99  -1 159 GLU B OE2 1 
ATOM   6875 N  N   . LYS B 2 160 ? 133.592 137.743 113.250 1.00 97.77  0  160 LYS B N   1 
ATOM   6876 C  CA  . LYS B 2 160 ? 135.049 137.763 113.352 1.00 97.77  0  160 LYS B CA  1 
ATOM   6877 C  C   . LYS B 2 160 ? 135.517 138.790 114.380 1.00 97.77  0  160 LYS B C   1 
ATOM   6878 O  O   . LYS B 2 160 ? 136.459 138.536 115.139 1.00 97.77  0  160 LYS B O   1 
ATOM   6879 C  CB  . LYS B 2 160 ? 135.666 138.048 111.983 1.00 97.77  0  160 LYS B CB  1 
ATOM   6880 C  CG  . LYS B 2 160 ? 136.276 136.827 111.316 1.00 97.77  0  160 LYS B CG  1 
ATOM   6881 C  CD  . LYS B 2 160 ? 135.203 135.841 110.883 1.00 97.77  0  160 LYS B CD  1 
ATOM   6882 C  CE  . LYS B 2 160 ? 135.808 134.655 110.149 1.00 97.77  0  160 LYS B CE  1 
ATOM   6883 N  NZ  . LYS B 2 160 ? 134.787 133.618 109.834 1.00 97.77  1  160 LYS B NZ  1 
ATOM   6884 N  N   . TRP B 2 161 ? 134.877 139.961 114.409 1.00 97.42  0  161 TRP B N   1 
ATOM   6885 C  CA  . TRP B 2 161 ? 135.206 140.998 115.379 1.00 97.42  0  161 TRP B CA  1 
ATOM   6886 C  C   . TRP B 2 161 ? 134.884 140.570 116.803 1.00 97.42  0  161 TRP B C   1 
ATOM   6887 O  O   . TRP B 2 161 ? 135.519 141.036 117.749 1.00 97.42  -1 161 TRP B O   1 
ATOM   6888 C  CB  . TRP B 2 161 ? 134.450 142.282 115.029 1.00 97.42  0  161 TRP B CB  1 
ATOM   6889 C  CG  . TRP B 2 161 ? 134.268 143.241 116.169 1.00 97.42  0  161 TRP B CG  1 
ATOM   6890 C  CD1 . TRP B 2 161 ? 133.089 143.621 116.739 1.00 97.42  0  161 TRP B CD1 1 
ATOM   6891 C  CD2 . TRP B 2 161 ? 135.295 143.976 116.845 1.00 97.42  0  161 TRP B CD2 1 
ATOM   6892 N  NE1 . TRP B 2 161 ? 133.319 144.528 117.744 1.00 97.42  0  161 TRP B NE1 1 
ATOM   6893 C  CE2 . TRP B 2 161 ? 134.666 144.764 117.828 1.00 97.42  0  161 TRP B CE2 1 
ATOM   6894 C  CE3 . TRP B 2 161 ? 136.687 144.036 116.722 1.00 97.42  0  161 TRP B CE3 1 
ATOM   6895 C  CZ2 . TRP B 2 161 ? 135.379 145.603 118.682 1.00 97.42  0  161 TRP B CZ2 1 
ATOM   6896 C  CZ3 . TRP B 2 161 ? 137.393 144.868 117.571 1.00 97.42  0  161 TRP B CZ3 1 
ATOM   6897 C  CH2 . TRP B 2 161 ? 136.738 145.642 118.537 1.00 97.42  0  161 TRP B CH2 1 
ATOM   6898 N  N   . GLU B 2 162 ? 133.997 139.587 116.962 1.00 100.46 0  162 GLU B N   1 
ATOM   6899 C  CA  . GLU B 2 162 ? 133.712 139.004 118.273 1.00 100.46 0  162 GLU B CA  1 
ATOM   6900 C  C   . GLU B 2 162 ? 134.970 138.401 118.898 1.00 100.46 0  162 GLU B C   1 
ATOM   6901 O  O   . GLU B 2 162 ? 134.973 138.013 120.072 1.00 100.46 0  162 GLU B O   1 
ATOM   6902 C  CB  . GLU B 2 162 ? 132.613 137.945 118.166 1.00 100.46 0  162 GLU B CB  1 
ATOM   6903 C  CG  . GLU B 2 162 ? 131.245 138.503 117.810 1.00 100.46 0  162 GLU B CG  1 
ATOM   6904 C  CD  . GLU B 2 162 ? 130.194 137.420 117.666 1.00 100.46 0  162 GLU B CD  1 
ATOM   6905 O  OE1 . GLU B 2 162 ? 130.565 136.227 117.654 1.00 100.46 0  162 GLU B OE1 1 
ATOM   6906 O  OE2 . GLU B 2 162 ? 128.996 137.761 117.564 1.00 100.46 -1 162 GLU B OE2 1 
ATOM   6907 N  N   . LEU B 2 163 ? 136.056 138.328 118.125 1.00 102.73 0  163 LEU B N   1 
ATOM   6908 C  CA  . LEU B 2 163 ? 137.356 138.045 118.719 1.00 102.73 0  163 LEU B CA  1 
ATOM   6909 C  C   . LEU B 2 163 ? 137.788 139.143 119.682 1.00 102.73 0  163 LEU B C   1 
ATOM   6910 O  O   . LEU B 2 163 ? 138.712 138.929 120.470 1.00 102.73 0  163 LEU B O   1 
ATOM   6911 C  CB  . LEU B 2 163 ? 138.415 137.848 117.632 1.00 102.73 0  163 LEU B CB  1 
ATOM   6912 C  CG  . LEU B 2 163 ? 138.623 136.428 117.091 1.00 102.73 0  163 LEU B CG  1 
ATOM   6913 C  CD1 . LEU B 2 163 ? 139.175 135.528 118.187 1.00 102.73 0  163 LEU B CD1 1 
ATOM   6914 C  CD2 . LEU B 2 163 ? 137.346 135.834 116.513 1.00 102.73 0  163 LEU B CD2 1 
ATOM   6915 N  N   . GLN B 2 164 ? 137.148 140.315 119.633 1.00 104.68 0  164 GLN B N   1 
ATOM   6916 C  CA  . GLN B 2 164 ? 137.352 141.313 120.679 1.00 104.68 0  164 GLN B CA  1 
ATOM   6917 C  C   . GLN B 2 164 ? 136.839 140.804 122.021 1.00 104.68 0  164 GLN B C   1 
ATOM   6918 O  O   . GLN B 2 164 ? 137.522 140.915 123.045 1.00 104.68 0  164 GLN B O   1 
ATOM   6919 C  CB  . GLN B 2 164 ? 136.661 142.622 120.297 1.00 104.68 0  164 GLN B CB  1 
ATOM   6920 C  CG  . GLN B 2 164 ? 136.442 143.583 121.458 1.00 104.68 0  164 GLN B CG  1 
ATOM   6921 C  CD  . GLN B 2 164 ? 137.727 143.928 122.185 1.00 104.68 0  164 GLN B CD  1 
ATOM   6922 O  OE1 . GLN B 2 164 ? 138.674 144.440 121.588 1.00 104.68 0  164 GLN B OE1 1 
ATOM   6923 N  NE2 . GLN B 2 164 ? 137.766 143.650 123.483 1.00 104.68 0  164 GLN B NE2 1 
ATOM   6924 N  N   . ARG B 2 165 ? 135.627 140.241 122.033 1.00 106.23 0  165 ARG B N   1 
ATOM   6925 C  CA  . ARG B 2 165 ? 135.122 139.603 123.245 1.00 106.23 0  165 ARG B CA  1 
ATOM   6926 C  C   . ARG B 2 165 ? 135.973 138.397 123.616 1.00 106.23 0  165 ARG B C   1 
ATOM   6927 O  O   . ARG B 2 165 ? 136.237 138.150 124.799 1.00 106.23 0  165 ARG B O   1 
ATOM   6928 C  CB  . ARG B 2 165 ? 133.664 139.183 123.058 1.00 106.23 0  165 ARG B CB  1 
ATOM   6929 C  CG  . ARG B 2 165 ? 132.640 140.228 123.467 1.00 106.23 0  165 ARG B CG  1 
ATOM   6930 C  CD  . ARG B 2 165 ? 132.392 141.232 122.356 1.00 106.23 0  165 ARG B CD  1 
ATOM   6931 N  NE  . ARG B 2 165 ? 131.228 142.066 122.632 1.00 106.23 0  165 ARG B NE  1 
ATOM   6932 C  CZ  . ARG B 2 165 ? 129.979 141.725 122.345 1.00 106.23 0  165 ARG B CZ  1 
ATOM   6933 N  NH1 . ARG B 2 165 ? 129.693 140.569 121.768 1.00 106.23 1  165 ARG B NH1 1 
ATOM   6934 N  NH2 . ARG B 2 165 ? 128.992 142.564 122.645 1.00 106.23 0  165 ARG B NH2 1 
ATOM   6935 N  N   . SER B 2 166 ? 136.400 137.628 122.613 1.00 105.51 0  166 SER B N   1 
ATOM   6936 C  CA  . SER B 2 166 ? 137.264 136.480 122.870 1.00 105.51 0  166 SER B CA  1 
ATOM   6937 C  C   . SER B 2 166 ? 138.587 136.898 123.502 1.00 105.51 0  166 SER B C   1 
ATOM   6938 O  O   . SER B 2 166 ? 139.176 136.132 124.273 1.00 105.51 0  166 SER B O   1 
ATOM   6939 C  CB  . SER B 2 166 ? 137.515 135.709 121.574 1.00 105.51 0  166 SER B CB  1 
ATOM   6940 O  OG  . SER B 2 166 ? 138.392 134.618 121.790 1.00 105.51 0  166 SER B OG  1 
ATOM   6941 N  N   . LEU B 2 167 ? 139.073 138.100 123.182 1.00 104.97 0  167 LEU B N   1 
ATOM   6942 C  CA  . LEU B 2 167 ? 140.323 138.585 123.759 1.00 104.97 0  167 LEU B CA  1 
ATOM   6943 C  C   . LEU B 2 167 ? 140.195 138.769 125.266 1.00 104.97 0  167 LEU B C   1 
ATOM   6944 O  O   . LEU B 2 167 ? 141.105 138.414 126.025 1.00 104.97 0  167 LEU B O   1 
ATOM   6945 C  CB  . LEU B 2 167 ? 140.735 139.894 123.083 1.00 104.97 0  167 LEU B CB  1 
ATOM   6946 C  CG  . LEU B 2 167 ? 142.127 140.446 123.400 1.00 104.97 0  167 LEU B CG  1 
ATOM   6947 C  CD1 . LEU B 2 167 ? 142.800 140.950 122.134 1.00 104.97 0  167 LEU B CD1 1 
ATOM   6948 C  CD2 . LEU B 2 167 ? 142.049 141.554 124.441 1.00 104.97 0  167 LEU B CD2 1 
ATOM   6949 N  N   . SER B 2 168 ? 139.073 139.325 125.717 1.00 105.61 0  168 SER B N   1 
ATOM   6950 C  CA  . SER B 2 168 ? 138.819 139.459 127.145 1.00 105.61 0  168 SER B CA  1 
ATOM   6951 C  C   . SER B 2 168 ? 138.448 138.101 127.724 1.00 105.61 0  168 SER B C   1 
ATOM   6952 O  O   . SER B 2 168 ? 137.267 137.742 127.778 1.00 105.61 0  168 SER B O   1 
ATOM   6953 C  CB  . SER B 2 168 ? 137.711 140.481 127.406 1.00 105.61 0  168 SER B CB  1 
ATOM   6954 O  OG  . SER B 2 168 ? 136.597 140.253 126.561 1.00 105.61 0  168 SER B OG  1 
ATOM   6955 N  N   . LYS B 2 169 ? 139.450 137.341 128.157 1.00 106.58 0  169 LYS B N   1 
ATOM   6956 C  CA  . LYS B 2 169 ? 139.273 135.968 128.615 1.00 106.58 0  169 LYS B CA  1 
ATOM   6957 C  C   . LYS B 2 169 ? 139.829 135.803 130.022 1.00 106.58 0  169 LYS B C   1 
ATOM   6958 O  O   . LYS B 2 169 ? 140.578 134.871 130.321 1.00 106.58 0  169 LYS B O   1 
ATOM   6959 C  CB  . LYS B 2 169 ? 139.932 134.985 127.652 1.00 106.58 0  169 LYS B CB  1 
ATOM   6960 C  CG  . LYS B 2 169 ? 139.163 133.688 127.469 1.00 106.58 0  169 LYS B CG  1 
ATOM   6961 C  CD  . LYS B 2 169 ? 137.788 133.945 126.873 1.00 106.58 0  169 LYS B CD  1 
ATOM   6962 C  CE  . LYS B 2 169 ? 137.024 132.649 126.663 1.00 106.58 0  169 LYS B CE  1 
ATOM   6963 N  NZ  . LYS B 2 169 ? 135.635 132.896 126.185 1.00 106.58 1  169 LYS B NZ  1 
ATOM   6964 N  N   . HIS B 2 170 ? 139.460 136.723 130.912 1.00 108.14 0  170 HIS B N   1 
ATOM   6965 C  CA  . HIS B 2 170 ? 139.866 136.659 132.315 1.00 108.14 0  170 HIS B CA  1 
ATOM   6966 C  C   . HIS B 2 170 ? 139.187 135.523 133.078 1.00 108.14 0  170 HIS B C   1 
ATOM   6967 O  O   . HIS B 2 170 ? 139.377 135.408 134.297 1.00 108.14 0  170 HIS B O   1 
ATOM   6968 C  CB  . HIS B 2 170 ? 139.579 137.996 133.002 1.00 108.14 0  170 HIS B CB  1 
ATOM   6969 C  CG  . HIS B 2 170 ? 140.409 138.237 134.224 1.00 108.14 0  170 HIS B CG  1 
ATOM   6970 N  ND1 . HIS B 2 170 ? 139.968 138.999 135.285 1.00 108.14 0  170 HIS B ND1 1 
ATOM   6971 C  CD2 . HIS B 2 170 ? 141.653 137.816 134.554 1.00 108.14 0  170 HIS B CD2 1 
ATOM   6972 C  CE1 . HIS B 2 170 ? 140.905 139.038 136.216 1.00 108.14 0  170 HIS B CE1 1 
ATOM   6973 N  NE2 . HIS B 2 170 ? 141.938 138.328 135.797 1.00 108.14 0  170 HIS B NE2 1 
ATOM   6974 N  N   . ASN B 2 171 ? 138.408 134.681 132.397 1.00 105.34 0  171 ASN B N   1 
ATOM   6975 C  CA  . ASN B 2 171 ? 137.755 133.536 133.020 1.00 105.34 0  171 ASN B CA  1 
ATOM   6976 C  C   . ASN B 2 171 ? 138.732 132.437 133.413 1.00 105.34 0  171 ASN B C   1 
ATOM   6977 O  O   . ASN B 2 171 ? 138.306 131.447 134.019 1.00 105.34 0  171 ASN B O   1 
ATOM   6978 C  CB  . ASN B 2 171 ? 136.690 132.968 132.079 1.00 105.34 0  171 ASN B CB  1 
ATOM   6979 C  CG  . ASN B 2 171 ? 135.564 133.947 131.815 1.00 105.34 0  171 ASN B CG  1 
ATOM   6980 O  OD1 . ASN B 2 171 ? 135.174 134.168 130.668 1.00 105.34 0  171 ASN B OD1 1 
ATOM   6981 N  ND2 . ASN B 2 171 ? 135.034 134.541 132.878 1.00 105.34 0  171 ASN B ND2 1 
ATOM   6982 N  N   . ARG B 2 172 ? 140.018 132.579 133.088 1.00 95.40  0  172 ARG B N   1 
ATOM   6983 C  CA  . ARG B 2 172 ? 141.027 131.575 133.422 1.00 95.40  0  172 ARG B CA  1 
ATOM   6984 C  C   . ARG B 2 172 ? 141.395 131.662 134.906 1.00 95.40  0  172 ARG B C   1 
ATOM   6985 O  O   . ARG B 2 172 ? 142.536 131.921 135.289 1.00 95.40  0  172 ARG B O   1 
ATOM   6986 C  CB  . ARG B 2 172 ? 142.256 131.754 132.540 1.00 95.40  0  172 ARG B CB  1 
ATOM   6987 C  CG  . ARG B 2 172 ? 141.967 131.785 131.048 1.00 95.40  0  172 ARG B CG  1 
ATOM   6988 C  CD  . ARG B 2 172 ? 143.244 132.025 130.258 1.00 95.40  0  172 ARG B CD  1 
ATOM   6989 N  NE  . ARG B 2 172 ? 144.116 130.857 130.264 1.00 95.40  0  172 ARG B NE  1 
ATOM   6990 C  CZ  . ARG B 2 172 ? 144.910 130.511 129.260 1.00 95.40  0  172 ARG B CZ  1 
ATOM   6991 N  NH1 . ARG B 2 172 ? 145.000 131.248 128.165 1.00 95.40  1  172 ARG B NH1 1 
ATOM   6992 N  NH2 . ARG B 2 172 ? 145.639 129.403 129.361 1.00 95.40  0  172 ARG B NH2 1 
ATOM   6993 N  N   . SER B 2 173 ? 140.388 131.435 135.751 1.00 97.22  0  173 SER B N   1 
ATOM   6994 C  CA  . SER B 2 173 ? 140.557 131.493 137.194 1.00 97.22  0  173 SER B CA  1 
ATOM   6995 C  C   . SER B 2 173 ? 140.326 130.161 137.891 1.00 97.22  0  173 SER B C   1 
ATOM   6996 O  O   . SER B 2 173 ? 140.705 130.027 139.061 1.00 97.22  0  173 SER B O   1 
ATOM   6997 C  CB  . SER B 2 173 ? 139.614 132.544 137.803 1.00 97.22  0  173 SER B CB  1 
ATOM   6998 O  OG  . SER B 2 173 ? 139.940 133.846 137.348 1.00 97.22  0  173 SER B OG  1 
ATOM   6999 N  N   . ASN B 2 174 ? 139.711 129.190 137.211 1.00 94.61  0  174 ASN B N   1 
ATOM   7000 C  CA  . ASN B 2 174 ? 139.513 127.838 137.808 1.00 94.61  0  174 ASN B CA  1 
ATOM   7001 C  C   . ASN B 2 174 ? 138.640 127.948 139.061 1.00 94.61  0  174 ASN B C   1 
ATOM   7002 O  O   . ASN B 2 174 ? 138.955 127.265 140.055 1.00 94.61  0  174 ASN B O   1 
ATOM   7003 C  CB  . ASN B 2 174 ? 140.842 127.143 138.114 1.00 94.61  0  174 ASN B CB  1 
ATOM   7004 C  CG  . ASN B 2 174 ? 140.707 125.639 138.218 1.00 94.61  0  174 ASN B CG  1 
ATOM   7005 O  OD1 . ASN B 2 174 ? 140.342 124.976 137.250 1.00 94.61  0  174 ASN B OD1 1 
ATOM   7006 N  ND2 . ASN B 2 174 ? 140.995 125.093 139.388 1.00 94.61  0  174 ASN B ND2 1 
ATOM   7007 N  N   . ILE B 2 175 ? 137.593 128.772 139.018 1.00 94.11  0  175 ILE B N   1 
ATOM   7008 C  CA  . ILE B 2 175 ? 136.667 128.947 140.131 1.00 94.11  0  175 ILE B CA  1 
ATOM   7009 C  C   . ILE B 2 175 ? 135.289 128.508 139.659 1.00 94.11  0  175 ILE B C   1 
ATOM   7010 O  O   . ILE B 2 175 ? 134.789 129.004 138.641 1.00 94.11  0  175 ILE B O   1 
ATOM   7011 C  CB  . ILE B 2 175 ? 136.641 130.399 140.635 1.00 94.11  0  175 ILE B CB  1 
ATOM   7012 C  CG1 . ILE B 2 175 ? 137.973 130.756 141.297 1.00 94.11  0  175 ILE B CG1 1 
ATOM   7013 C  CG2 . ILE B 2 175 ? 135.487 130.606 141.604 1.00 94.11  0  175 ILE B CG2 1 
ATOM   7014 C  CD1 . ILE B 2 175 ? 137.974 132.107 141.981 1.00 94.11  0  175 ILE B CD1 1 
ATOM   7015 N  N   . GLY B 2 176 ? 134.678 127.582 140.394 1.00 93.35  0  176 GLY B N   1 
ATOM   7016 C  CA  . GLY B 2 176 ? 133.393 127.035 140.019 1.00 93.35  0  176 GLY B CA  1 
ATOM   7017 C  C   . GLY B 2 176 ? 133.446 125.909 139.010 1.00 93.35  0  176 GLY B C   1 
ATOM   7018 O  O   . GLY B 2 176 ? 132.386 125.407 138.613 1.00 93.35  0  176 GLY B O   1 
ATOM   7019 N  N   . THR B 2 177 ? 134.638 125.502 138.580 1.00 90.69  0  177 THR B N   1 
ATOM   7020 C  CA  . THR B 2 177 ? 134.763 124.393 137.646 1.00 90.69  0  177 THR B CA  1 
ATOM   7021 C  C   . THR B 2 177 ? 134.301 123.097 138.306 1.00 90.69  0  177 THR B C   1 
ATOM   7022 O  O   . THR B 2 177 ? 134.404 122.923 139.523 1.00 90.69  0  177 THR B O   1 
ATOM   7023 C  CB  . THR B 2 177 ? 136.212 124.263 137.171 1.00 90.69  0  177 THR B CB  1 
ATOM   7024 O  OG1 . THR B 2 177 ? 136.704 125.554 136.788 1.00 90.69  0  177 THR B OG1 1 
ATOM   7025 C  CG2 . THR B 2 177 ? 136.311 123.328 135.973 1.00 90.69  0  177 THR B CG2 1 
ATOM   7026 N  N   . GLU B 2 178 ? 133.766 122.187 137.485 1.00 87.10  0  178 GLU B N   1 
ATOM   7027 C  CA  . GLU B 2 178 ? 133.257 120.919 138.000 1.00 87.10  0  178 GLU B CA  1 
ATOM   7028 C  C   . GLU B 2 178 ? 134.341 120.154 138.750 1.00 87.10  0  178 GLU B C   1 
ATOM   7029 O  O   . GLU B 2 178 ? 134.126 119.687 139.875 1.00 87.10  0  178 GLU B O   1 
ATOM   7030 C  CB  . GLU B 2 178 ? 132.696 120.081 136.849 1.00 87.10  0  178 GLU B CB  1 
ATOM   7031 C  CG  . GLU B 2 178 ? 132.006 118.797 137.281 1.00 87.10  0  178 GLU B CG  1 
ATOM   7032 C  CD  . GLU B 2 178 ? 132.922 117.591 137.216 1.00 87.10  0  178 GLU B CD  1 
ATOM   7033 O  OE1 . GLU B 2 178 ? 133.839 117.584 136.368 1.00 87.10  0  178 GLU B OE1 1 
ATOM   7034 O  OE2 . GLU B 2 178 ? 132.724 116.648 138.011 1.00 87.10  -1 178 GLU B OE2 1 
ATOM   7035 N  N   . GLY B 2 179 ? 135.514 120.014 138.141 1.00 81.18  0  179 GLY B N   1 
ATOM   7036 C  CA  . GLY B 2 179 ? 136.643 119.403 138.813 1.00 81.18  0  179 GLY B CA  1 
ATOM   7037 C  C   . GLY B 2 179 ? 137.569 120.425 139.439 1.00 81.18  0  179 GLY B C   1 
ATOM   7038 O  O   . GLY B 2 179 ? 138.787 120.366 139.243 1.00 81.18  0  179 GLY B O   1 
ATOM   7039 N  N   . GLY B 2 180 ? 137.009 121.366 140.195 1.00 73.21  0  180 GLY B N   1 
ATOM   7040 C  CA  . GLY B 2 180 ? 137.784 122.447 140.755 1.00 73.21  0  180 GLY B CA  1 
ATOM   7041 C  C   . GLY B 2 180 ? 137.598 122.612 142.249 1.00 73.21  0  180 GLY B C   1 
ATOM   7042 O  O   . GLY B 2 180 ? 136.985 121.778 142.923 1.00 73.21  0  180 GLY B O   1 
ATOM   7043 N  N   . PRO B 2 181 ? 138.138 123.704 142.797 1.00 65.87  0  181 PRO B N   1 
ATOM   7044 C  CA  . PRO B 2 181 ? 138.048 123.915 144.240 1.00 65.87  0  181 PRO B CA  1 
ATOM   7045 C  C   . PRO B 2 181 ? 136.620 124.210 144.657 1.00 65.87  0  181 PRO B C   1 
ATOM   7046 O  O   . PRO B 2 181 ? 135.822 124.737 143.862 1.00 65.87  0  181 PRO B O   1 
ATOM   7047 C  CB  . PRO B 2 181 ? 138.963 125.131 144.478 1.00 65.87  0  181 PRO B CB  1 
ATOM   7048 C  CG  . PRO B 2 181 ? 139.762 125.287 143.214 1.00 65.87  0  181 PRO B CG  1 
ATOM   7049 C  CD  . PRO B 2 181 ? 138.876 124.784 142.128 1.00 65.87  0  181 PRO B CD  1 
ATOM   7050 N  N   . PRO B 2 182 ? 136.246 123.879 145.889 1.00 62.51  0  182 PRO B N   1 
ATOM   7051 C  CA  . PRO B 2 182 ? 134.913 124.236 146.387 1.00 62.51  0  182 PRO B CA  1 
ATOM   7052 C  C   . PRO B 2 182 ? 134.742 125.743 146.436 1.00 62.51  0  182 PRO B C   1 
ATOM   7053 O  O   . PRO B 2 182 ? 135.689 126.474 146.764 1.00 62.51  0  182 PRO B O   1 
ATOM   7054 C  CB  . PRO B 2 182 ? 134.876 123.624 147.796 1.00 62.51  0  182 PRO B CB  1 
ATOM   7055 C  CG  . PRO B 2 182 ? 136.010 122.659 147.852 1.00 62.51  0  182 PRO B CG  1 
ATOM   7056 C  CD  . PRO B 2 182 ? 137.036 123.127 146.877 1.00 62.51  0  182 PRO B CD  1 
ATOM   7057 N  N   . PRO B 2 183 ? 133.553 126.247 146.120 1.00 62.17  0  183 PRO B N   1 
ATOM   7058 C  CA  . PRO B 2 183 ? 133.329 127.693 146.126 1.00 62.17  0  183 PRO B CA  1 
ATOM   7059 C  C   . PRO B 2 183 ? 132.940 128.209 147.505 1.00 62.17  0  183 PRO B C   1 
ATOM   7060 O  O   . PRO B 2 183 ? 132.468 127.471 148.373 1.00 62.17  0  183 PRO B O   1 
ATOM   7061 C  CB  . PRO B 2 183 ? 132.170 127.874 145.130 1.00 62.17  0  183 PRO B CB  1 
ATOM   7062 C  CG  . PRO B 2 183 ? 131.637 126.474 144.842 1.00 62.17  0  183 PRO B CG  1 
ATOM   7063 C  CD  . PRO B 2 183 ? 132.338 125.510 145.747 1.00 62.17  0  183 PRO B CD  1 
ATOM   7064 N  N   . PHE B 2 184 ? 133.153 129.510 147.690 1.00 62.39  0  184 PHE B N   1 
ATOM   7065 C  CA  . PHE B 2 184 ? 132.810 130.188 148.939 1.00 62.39  0  184 PHE B CA  1 
ATOM   7066 C  C   . PHE B 2 184 ? 131.399 130.746 148.807 1.00 62.39  0  184 PHE B C   1 
ATOM   7067 O  O   . PHE B 2 184 ? 131.181 131.775 148.163 1.00 62.39  0  184 PHE B O   1 
ATOM   7068 C  CB  . PHE B 2 184 ? 133.817 131.288 149.252 1.00 62.39  0  184 PHE B CB  1 
ATOM   7069 C  CG  . PHE B 2 184 ? 133.374 132.223 150.340 1.00 62.39  0  184 PHE B CG  1 
ATOM   7070 C  CD1 . PHE B 2 184 ? 133.242 131.777 151.644 1.00 62.39  0  184 PHE B CD1 1 
ATOM   7071 C  CD2 . PHE B 2 184 ? 133.087 133.547 150.059 1.00 62.39  0  184 PHE B CD2 1 
ATOM   7072 C  CE1 . PHE B 2 184 ? 132.834 132.634 152.647 1.00 62.39  0  184 PHE B CE1 1 
ATOM   7073 C  CE2 . PHE B 2 184 ? 132.679 134.409 151.057 1.00 62.39  0  184 PHE B CE2 1 
ATOM   7074 C  CZ  . PHE B 2 184 ? 132.552 133.952 152.352 1.00 62.39  0  184 PHE B CZ  1 
ATOM   7075 N  N   . VAL B 2 185 ? 130.437 130.064 149.415 1.00 63.28  0  185 VAL B N   1 
ATOM   7076 C  CA  . VAL B 2 185 ? 129.053 130.550 149.406 1.00 63.28  0  185 VAL B CA  1 
ATOM   7077 C  C   . VAL B 2 185 ? 128.951 131.788 150.290 1.00 63.28  0  185 VAL B C   1 
ATOM   7078 O  O   . VAL B 2 185 ? 129.592 131.837 151.356 1.00 63.28  0  185 VAL B O   1 
ATOM   7079 C  CB  . VAL B 2 185 ? 128.098 129.441 149.867 1.00 63.28  0  185 VAL B CB  1 
ATOM   7080 C  CG1 . VAL B 2 185 ? 128.353 129.060 151.318 1.00 63.28  0  185 VAL B CG1 1 
ATOM   7081 C  CG2 . VAL B 2 185 ? 126.645 129.853 149.667 1.00 63.28  0  185 VAL B CG2 1 
ATOM   7082 N  N   . PRO B 2 186 ? 128.214 132.822 149.882 1.00 63.72  0  186 PRO B N   1 
ATOM   7083 C  CA  . PRO B 2 186 ? 128.099 134.018 150.724 1.00 63.72  0  186 PRO B CA  1 
ATOM   7084 C  C   . PRO B 2 186 ? 127.404 133.715 152.043 1.00 63.72  0  186 PRO B C   1 
ATOM   7085 O  O   . PRO B 2 186 ? 126.584 132.801 152.146 1.00 63.72  0  186 PRO B O   1 
ATOM   7086 C  CB  . PRO B 2 186 ? 127.273 134.981 149.864 1.00 63.72  0  186 PRO B CB  1 
ATOM   7087 C  CG  . PRO B 2 186 ? 127.498 134.519 148.464 1.00 63.72  0  186 PRO B CG  1 
ATOM   7088 C  CD  . PRO B 2 186 ? 127.620 133.028 148.550 1.00 63.72  0  186 PRO B CD  1 
ATOM   7089 N  N   . PHE B 2 187 ? 127.753 134.525 153.046 1.00 63.87  0  187 PHE B N   1 
ATOM   7090 C  CA  . PHE B 2 187 ? 127.219 134.303 154.410 1.00 63.87  0  187 PHE B CA  1 
ATOM   7091 C  C   . PHE B 2 187 ? 125.726 134.592 154.464 1.00 63.87  0  187 PHE B C   1 
ATOM   7092 O  O   . PHE B 2 187 ? 125.258 135.514 153.773 1.00 63.87  0  187 PHE B O   1 
ATOM   7093 C  CB  . PHE B 2 187 ? 127.965 135.181 155.417 1.00 63.87  0  187 PHE B CB  1 
ATOM   7094 C  CG  . PHE B 2 187 ? 129.213 134.569 156.000 1.00 63.87  0  187 PHE B CG  1 
ATOM   7095 C  CD1 . PHE B 2 187 ? 129.140 133.662 157.044 1.00 63.87  0  187 PHE B CD1 1 
ATOM   7096 C  CD2 . PHE B 2 187 ? 130.464 134.911 155.512 1.00 63.87  0  187 PHE B CD2 1 
ATOM   7097 C  CE1 . PHE B 2 187 ? 130.289 133.105 157.583 1.00 63.87  0  187 PHE B CE1 1 
ATOM   7098 C  CE2 . PHE B 2 187 ? 131.612 134.353 156.051 1.00 63.87  0  187 PHE B CE2 1 
ATOM   7099 C  CZ  . PHE B 2 187 ? 131.522 133.451 157.084 1.00 63.87  0  187 PHE B CZ  1 
ATOM   7100 N  N   . GLY B 2 188 ? 125.010 133.822 155.274 1.00 71.43  0  188 GLY B N   1 
ATOM   7101 C  CA  . GLY B 2 188 ? 123.587 133.997 155.461 1.00 71.43  0  188 GLY B CA  1 
ATOM   7102 C  C   . GLY B 2 188 ? 123.271 135.076 156.480 1.00 71.43  0  188 GLY B C   1 
ATOM   7103 O  O   . GLY B 2 188 ? 124.140 135.815 156.946 1.00 71.43  0  188 GLY B O   1 
ATOM   7104 N  N   . GLN B 2 189 ? 121.991 135.159 156.826 1.00 77.86  0  189 GLN B N   1 
ATOM   7105 C  CA  . GLN B 2 189 ? 121.524 136.147 157.792 1.00 77.86  0  189 GLN B CA  1 
ATOM   7106 C  C   . GLN B 2 189 ? 120.941 135.473 159.029 1.00 77.86  0  189 GLN B C   1 
ATOM   7107 O  O   . GLN B 2 189 ? 121.138 135.939 160.152 1.00 77.86  0  189 GLN B O   1 
ATOM   7108 C  CB  . GLN B 2 189 ? 120.483 137.069 157.153 1.00 77.86  0  189 GLN B CB  1 
ATOM   7109 C  CG  . GLN B 2 189 ? 121.069 138.317 156.514 1.00 77.86  0  189 GLN B CG  1 
ATOM   7110 C  CD  . GLN B 2 189 ? 121.601 138.061 155.118 1.00 77.86  0  189 GLN B CD  1 
ATOM   7111 O  OE1 . GLN B 2 189 ? 120.837 137.807 154.187 1.00 77.86  0  189 GLN B OE1 1 
ATOM   7112 N  NE2 . GLN B 2 189 ? 122.918 138.129 154.965 1.00 77.86  0  189 GLN B NE2 1 
HETATM 7113 MN MN  . MN  C 3 .   ? 145.650 147.412 173.432 1.00 78.77  0  801 MN  A MN  1 
HETATM 7114 ZN ZN  . ZN  D 4 .   ? 144.113 125.964 121.431 1.00 85.74  0  802 ZN  A ZN  1 
HETATM 7115 ZN ZN  . ZN  E 4 .   ? 157.722 133.429 132.369 1.00 83.96  0  803 ZN  A ZN  1 
HETATM 7116 ZN ZN  . ZN  F 4 .   ? 147.317 129.141 124.935 1.00 98.35  0  804 ZN  A ZN  1 
# 
