data_9CA3
# 
_entry.id   9CA3 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9CA3         pdb_00009ca3 10.2210/pdb9ca3/pdb 
WWPDB D_1000285088 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-02 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9CA3 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-16 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              feradical@utsa.edu 
_pdbx_contact_author.name_first         Aimin 
_pdbx_contact_author.name_last          Liu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-4182-8176 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Shin, I.' 1 0000-0001-8111-8948 
'Liu, A.'  2 0000-0002-4182-8176 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Biol.Chem. 
_citation.journal_id_ASTM           JBCHA3 
_citation.journal_id_CSD            0071 
_citation.journal_id_ISSN           1083-351X 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            301 
_citation.language                  ? 
_citation.page_first                108241 
_citation.page_last                 108241 
_citation.title                     
;Structural insights into 2-oxindole-forming monooxygenase MarE: Divergent architecture and substrate positioning versus tryptophan dioxygenases.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.jbc.2025.108241 
_citation.pdbx_database_id_PubMed   39880093 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Shin, I.'      1 ? 
primary 'Nguyen, R.C.'  2 ? 
primary 'Montoya, S.R.' 3 ? 
primary 'Liu, A.'       4 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Tryptophan 2,3-dioxygenase'       32021.684 4   ? C280S ? 
'N-terminal histag was removed by TEV protease. Full-length. C280S mutant.' 
2 non-polymer syn 'PROTOPORPHYRIN IX CONTAINING FE'  616.487   4   ? ?     ? ? 
3 non-polymer syn 'CYANIDE ION'                      26.017    4   ? ?     ? ? 
4 non-polymer syn '(betaS)-beta-methyl-L-tryptophan' 218.252   4   ? ?     ? ? 
5 water       nat water                              18.015    520 ? ?     ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GHMKRSLNPDEPNALLSYDFDRGSNYENVLHLTDALGALVPESETEHPDQRFFQVTHLITEYAWVQVHYELRRAIGHLDE
DRYHQAVRMFDRATGLSEVTVQAVRLLTDHLPQHSLLMMRNALPEDATGLDSPGYRNLRRVARPVWKAYEQAVERAGLSL
QDVIAQQDDGYDGPRSGGSQSLALVREAMLRLDGSVLGWKQHHLIMVWSQLGGQPGLRKGNEEGDDGLELPQSLGGRSLA
TLEARSQLALFPELWRAAEDAYWLLGTRHDTDAPVRGGGNGSPVQH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GHMKRSLNPDEPNALLSYDFDRGSNYENVLHLTDALGALVPESETEHPDQRFFQVTHLITEYAWVQVHYELRRAIGHLDE
DRYHQAVRMFDRATGLSEVTVQAVRLLTDHLPQHSLLMMRNALPEDATGLDSPGYRNLRRVARPVWKAYEQAVERAGLSL
QDVIAQQDDGYDGPRSGGSQSLALVREAMLRLDGSVLGWKQHHLIMVWSQLGGQPGLRKGNEEGDDGLELPQSLGGRSLA
TLEARSQLALFPELWRAAEDAYWLLGTRHDTDAPVRGGGNGSPVQH
;
_entity_poly.pdbx_strand_id                 A,B,C,D 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'PROTOPORPHYRIN IX CONTAINING FE'  HEM 
3 'CYANIDE ION'                      CYN 
4 '(betaS)-beta-methyl-L-tryptophan' 78U 
5 water                              HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   HIS n 
1 3   MET n 
1 4   LYS n 
1 5   ARG n 
1 6   SER n 
1 7   LEU n 
1 8   ASN n 
1 9   PRO n 
1 10  ASP n 
1 11  GLU n 
1 12  PRO n 
1 13  ASN n 
1 14  ALA n 
1 15  LEU n 
1 16  LEU n 
1 17  SER n 
1 18  TYR n 
1 19  ASP n 
1 20  PHE n 
1 21  ASP n 
1 22  ARG n 
1 23  GLY n 
1 24  SER n 
1 25  ASN n 
1 26  TYR n 
1 27  GLU n 
1 28  ASN n 
1 29  VAL n 
1 30  LEU n 
1 31  HIS n 
1 32  LEU n 
1 33  THR n 
1 34  ASP n 
1 35  ALA n 
1 36  LEU n 
1 37  GLY n 
1 38  ALA n 
1 39  LEU n 
1 40  VAL n 
1 41  PRO n 
1 42  GLU n 
1 43  SER n 
1 44  GLU n 
1 45  THR n 
1 46  GLU n 
1 47  HIS n 
1 48  PRO n 
1 49  ASP n 
1 50  GLN n 
1 51  ARG n 
1 52  PHE n 
1 53  PHE n 
1 54  GLN n 
1 55  VAL n 
1 56  THR n 
1 57  HIS n 
1 58  LEU n 
1 59  ILE n 
1 60  THR n 
1 61  GLU n 
1 62  TYR n 
1 63  ALA n 
1 64  TRP n 
1 65  VAL n 
1 66  GLN n 
1 67  VAL n 
1 68  HIS n 
1 69  TYR n 
1 70  GLU n 
1 71  LEU n 
1 72  ARG n 
1 73  ARG n 
1 74  ALA n 
1 75  ILE n 
1 76  GLY n 
1 77  HIS n 
1 78  LEU n 
1 79  ASP n 
1 80  GLU n 
1 81  ASP n 
1 82  ARG n 
1 83  TYR n 
1 84  HIS n 
1 85  GLN n 
1 86  ALA n 
1 87  VAL n 
1 88  ARG n 
1 89  MET n 
1 90  PHE n 
1 91  ASP n 
1 92  ARG n 
1 93  ALA n 
1 94  THR n 
1 95  GLY n 
1 96  LEU n 
1 97  SER n 
1 98  GLU n 
1 99  VAL n 
1 100 THR n 
1 101 VAL n 
1 102 GLN n 
1 103 ALA n 
1 104 VAL n 
1 105 ARG n 
1 106 LEU n 
1 107 LEU n 
1 108 THR n 
1 109 ASP n 
1 110 HIS n 
1 111 LEU n 
1 112 PRO n 
1 113 GLN n 
1 114 HIS n 
1 115 SER n 
1 116 LEU n 
1 117 LEU n 
1 118 MET n 
1 119 MET n 
1 120 ARG n 
1 121 ASN n 
1 122 ALA n 
1 123 LEU n 
1 124 PRO n 
1 125 GLU n 
1 126 ASP n 
1 127 ALA n 
1 128 THR n 
1 129 GLY n 
1 130 LEU n 
1 131 ASP n 
1 132 SER n 
1 133 PRO n 
1 134 GLY n 
1 135 TYR n 
1 136 ARG n 
1 137 ASN n 
1 138 LEU n 
1 139 ARG n 
1 140 ARG n 
1 141 VAL n 
1 142 ALA n 
1 143 ARG n 
1 144 PRO n 
1 145 VAL n 
1 146 TRP n 
1 147 LYS n 
1 148 ALA n 
1 149 TYR n 
1 150 GLU n 
1 151 GLN n 
1 152 ALA n 
1 153 VAL n 
1 154 GLU n 
1 155 ARG n 
1 156 ALA n 
1 157 GLY n 
1 158 LEU n 
1 159 SER n 
1 160 LEU n 
1 161 GLN n 
1 162 ASP n 
1 163 VAL n 
1 164 ILE n 
1 165 ALA n 
1 166 GLN n 
1 167 GLN n 
1 168 ASP n 
1 169 ASP n 
1 170 GLY n 
1 171 TYR n 
1 172 ASP n 
1 173 GLY n 
1 174 PRO n 
1 175 ARG n 
1 176 SER n 
1 177 GLY n 
1 178 GLY n 
1 179 SER n 
1 180 GLN n 
1 181 SER n 
1 182 LEU n 
1 183 ALA n 
1 184 LEU n 
1 185 VAL n 
1 186 ARG n 
1 187 GLU n 
1 188 ALA n 
1 189 MET n 
1 190 LEU n 
1 191 ARG n 
1 192 LEU n 
1 193 ASP n 
1 194 GLY n 
1 195 SER n 
1 196 VAL n 
1 197 LEU n 
1 198 GLY n 
1 199 TRP n 
1 200 LYS n 
1 201 GLN n 
1 202 HIS n 
1 203 HIS n 
1 204 LEU n 
1 205 ILE n 
1 206 MET n 
1 207 VAL n 
1 208 TRP n 
1 209 SER n 
1 210 GLN n 
1 211 LEU n 
1 212 GLY n 
1 213 GLY n 
1 214 GLN n 
1 215 PRO n 
1 216 GLY n 
1 217 LEU n 
1 218 ARG n 
1 219 LYS n 
1 220 GLY n 
1 221 ASN n 
1 222 GLU n 
1 223 GLU n 
1 224 GLY n 
1 225 ASP n 
1 226 ASP n 
1 227 GLY n 
1 228 LEU n 
1 229 GLU n 
1 230 LEU n 
1 231 PRO n 
1 232 GLN n 
1 233 SER n 
1 234 LEU n 
1 235 GLY n 
1 236 GLY n 
1 237 ARG n 
1 238 SER n 
1 239 LEU n 
1 240 ALA n 
1 241 THR n 
1 242 LEU n 
1 243 GLU n 
1 244 ALA n 
1 245 ARG n 
1 246 SER n 
1 247 GLN n 
1 248 LEU n 
1 249 ALA n 
1 250 LEU n 
1 251 PHE n 
1 252 PRO n 
1 253 GLU n 
1 254 LEU n 
1 255 TRP n 
1 256 ARG n 
1 257 ALA n 
1 258 ALA n 
1 259 GLU n 
1 260 ASP n 
1 261 ALA n 
1 262 TYR n 
1 263 TRP n 
1 264 LEU n 
1 265 LEU n 
1 266 GLY n 
1 267 THR n 
1 268 ARG n 
1 269 HIS n 
1 270 ASP n 
1 271 THR n 
1 272 ASP n 
1 273 ALA n 
1 274 PRO n 
1 275 VAL n 
1 276 ARG n 
1 277 GLY n 
1 278 GLY n 
1 279 GLY n 
1 280 ASN n 
1 281 GLY n 
1 282 SER n 
1 283 PRO n 
1 284 VAL n 
1 285 GLN n 
1 286 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   286 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 marE 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Streptomyces sp. B9173' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1462558 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
78U non-polymer         . '(betaS)-beta-methyl-L-tryptophan' ?    'C12 H14 N2 O2'    218.252 
ALA 'L-peptide linking' y ALANINE                            ?    'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE                           ?    'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE                         ?    'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                    ?    'C4 H7 N O4'       133.103 
CYN non-polymer         . 'CYANIDE ION'                      ?    'C N -1'           26.017  
CYS 'L-peptide linking' y CYSTEINE                           ?    'C3 H7 N O2 S'     121.158 
GLN 'L-peptide linking' y GLUTAMINE                          ?    'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                    ?    'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE                            ?    'C2 H5 N O2'       75.067  
HEM non-polymer         . 'PROTOPORPHYRIN IX CONTAINING FE'  HEME 'C34 H32 Fe N4 O4' 616.487 
HIS 'L-peptide linking' y HISTIDINE                          ?    'C6 H10 N3 O2 1'   156.162 
HOH non-polymer         . WATER                              ?    'H2 O'             18.015  
ILE 'L-peptide linking' y ISOLEUCINE                         ?    'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE                            ?    'C6 H13 N O2'      131.173 
LYS 'L-peptide linking' y LYSINE                             ?    'C6 H15 N2 O2 1'   147.195 
MET 'L-peptide linking' y METHIONINE                         ?    'C5 H11 N O2 S'    149.211 
PHE 'L-peptide linking' y PHENYLALANINE                      ?    'C9 H11 N O2'      165.189 
PRO 'L-peptide linking' y PROLINE                            ?    'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE                             ?    'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE                          ?    'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                         ?    'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking' y TYROSINE                           ?    'C9 H11 N O3'      181.189 
VAL 'L-peptide linking' y VALINE                             ?    'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -1  ?   ?   ?   A . n 
A 1 2   HIS 2   0   ?   ?   ?   A . n 
A 1 3   MET 3   1   1   MET MET A . n 
A 1 4   LYS 4   2   2   LYS LYS A . n 
A 1 5   ARG 5   3   3   ARG ARG A . n 
A 1 6   SER 6   4   4   SER SER A . n 
A 1 7   LEU 7   5   5   LEU LEU A . n 
A 1 8   ASN 8   6   6   ASN ASN A . n 
A 1 9   PRO 9   7   7   PRO PRO A . n 
A 1 10  ASP 10  8   8   ASP ASP A . n 
A 1 11  GLU 11  9   9   GLU GLU A . n 
A 1 12  PRO 12  10  10  PRO PRO A . n 
A 1 13  ASN 13  11  11  ASN ASN A . n 
A 1 14  ALA 14  12  12  ALA ALA A . n 
A 1 15  LEU 15  13  13  LEU LEU A . n 
A 1 16  LEU 16  14  14  LEU LEU A . n 
A 1 17  SER 17  15  15  SER SER A . n 
A 1 18  TYR 18  16  16  TYR TYR A . n 
A 1 19  ASP 19  17  17  ASP ASP A . n 
A 1 20  PHE 20  18  18  PHE PHE A . n 
A 1 21  ASP 21  19  19  ASP ASP A . n 
A 1 22  ARG 22  20  20  ARG ARG A . n 
A 1 23  GLY 23  21  21  GLY GLY A . n 
A 1 24  SER 24  22  22  SER SER A . n 
A 1 25  ASN 25  23  23  ASN ASN A . n 
A 1 26  TYR 26  24  24  TYR TYR A . n 
A 1 27  GLU 27  25  25  GLU GLU A . n 
A 1 28  ASN 28  26  26  ASN ASN A . n 
A 1 29  VAL 29  27  27  VAL VAL A . n 
A 1 30  LEU 30  28  28  LEU LEU A . n 
A 1 31  HIS 31  29  29  HIS HIS A . n 
A 1 32  LEU 32  30  30  LEU LEU A . n 
A 1 33  THR 33  31  31  THR THR A . n 
A 1 34  ASP 34  32  32  ASP ASP A . n 
A 1 35  ALA 35  33  33  ALA ALA A . n 
A 1 36  LEU 36  34  34  LEU LEU A . n 
A 1 37  GLY 37  35  35  GLY GLY A . n 
A 1 38  ALA 38  36  36  ALA ALA A . n 
A 1 39  LEU 39  37  37  LEU LEU A . n 
A 1 40  VAL 40  38  38  VAL VAL A . n 
A 1 41  PRO 41  39  39  PRO PRO A . n 
A 1 42  GLU 42  40  40  GLU GLU A . n 
A 1 43  SER 43  41  41  SER SER A . n 
A 1 44  GLU 44  42  42  GLU GLU A . n 
A 1 45  THR 45  43  43  THR THR A . n 
A 1 46  GLU 46  44  44  GLU GLU A . n 
A 1 47  HIS 47  45  45  HIS HIS A . n 
A 1 48  PRO 48  46  46  PRO PRO A . n 
A 1 49  ASP 49  47  47  ASP ASP A . n 
A 1 50  GLN 50  48  48  GLN GLN A . n 
A 1 51  ARG 51  49  49  ARG ARG A . n 
A 1 52  PHE 52  50  50  PHE PHE A . n 
A 1 53  PHE 53  51  51  PHE PHE A . n 
A 1 54  GLN 54  52  52  GLN GLN A . n 
A 1 55  VAL 55  53  53  VAL VAL A . n 
A 1 56  THR 56  54  54  THR THR A . n 
A 1 57  HIS 57  55  55  HIS HIS A . n 
A 1 58  LEU 58  56  56  LEU LEU A . n 
A 1 59  ILE 59  57  57  ILE ILE A . n 
A 1 60  THR 60  58  58  THR THR A . n 
A 1 61  GLU 61  59  59  GLU GLU A . n 
A 1 62  TYR 62  60  60  TYR TYR A . n 
A 1 63  ALA 63  61  61  ALA ALA A . n 
A 1 64  TRP 64  62  62  TRP TRP A . n 
A 1 65  VAL 65  63  63  VAL VAL A . n 
A 1 66  GLN 66  64  64  GLN GLN A . n 
A 1 67  VAL 67  65  65  VAL VAL A . n 
A 1 68  HIS 68  66  66  HIS HIS A . n 
A 1 69  TYR 69  67  67  TYR TYR A . n 
A 1 70  GLU 70  68  68  GLU GLU A . n 
A 1 71  LEU 71  69  69  LEU LEU A . n 
A 1 72  ARG 72  70  70  ARG ARG A . n 
A 1 73  ARG 73  71  71  ARG ARG A . n 
A 1 74  ALA 74  72  72  ALA ALA A . n 
A 1 75  ILE 75  73  73  ILE ILE A . n 
A 1 76  GLY 76  74  74  GLY GLY A . n 
A 1 77  HIS 77  75  75  HIS HIS A . n 
A 1 78  LEU 78  76  76  LEU LEU A . n 
A 1 79  ASP 79  77  77  ASP ASP A . n 
A 1 80  GLU 80  78  78  GLU GLU A . n 
A 1 81  ASP 81  79  79  ASP ASP A . n 
A 1 82  ARG 82  80  80  ARG ARG A . n 
A 1 83  TYR 83  81  81  TYR TYR A . n 
A 1 84  HIS 84  82  82  HIS HIS A . n 
A 1 85  GLN 85  83  83  GLN GLN A . n 
A 1 86  ALA 86  84  84  ALA ALA A . n 
A 1 87  VAL 87  85  85  VAL VAL A . n 
A 1 88  ARG 88  86  86  ARG ARG A . n 
A 1 89  MET 89  87  87  MET MET A . n 
A 1 90  PHE 90  88  88  PHE PHE A . n 
A 1 91  ASP 91  89  89  ASP ASP A . n 
A 1 92  ARG 92  90  90  ARG ARG A . n 
A 1 93  ALA 93  91  91  ALA ALA A . n 
A 1 94  THR 94  92  92  THR THR A . n 
A 1 95  GLY 95  93  93  GLY GLY A . n 
A 1 96  LEU 96  94  94  LEU LEU A . n 
A 1 97  SER 97  95  95  SER SER A . n 
A 1 98  GLU 98  96  96  GLU GLU A . n 
A 1 99  VAL 99  97  97  VAL VAL A . n 
A 1 100 THR 100 98  98  THR THR A . n 
A 1 101 VAL 101 99  99  VAL VAL A . n 
A 1 102 GLN 102 100 100 GLN GLN A . n 
A 1 103 ALA 103 101 101 ALA ALA A . n 
A 1 104 VAL 104 102 102 VAL VAL A . n 
A 1 105 ARG 105 103 103 ARG ARG A . n 
A 1 106 LEU 106 104 104 LEU LEU A . n 
A 1 107 LEU 107 105 105 LEU LEU A . n 
A 1 108 THR 108 106 106 THR THR A . n 
A 1 109 ASP 109 107 107 ASP ASP A . n 
A 1 110 HIS 110 108 108 HIS HIS A . n 
A 1 111 LEU 111 109 109 LEU LEU A . n 
A 1 112 PRO 112 110 110 PRO PRO A . n 
A 1 113 GLN 113 111 111 GLN GLN A . n 
A 1 114 HIS 114 112 112 HIS HIS A . n 
A 1 115 SER 115 113 113 SER SER A . n 
A 1 116 LEU 116 114 114 LEU LEU A . n 
A 1 117 LEU 117 115 115 LEU LEU A . n 
A 1 118 MET 118 116 116 MET MET A . n 
A 1 119 MET 119 117 117 MET MET A . n 
A 1 120 ARG 120 118 118 ARG ARG A . n 
A 1 121 ASN 121 119 119 ASN ASN A . n 
A 1 122 ALA 122 120 120 ALA ALA A . n 
A 1 123 LEU 123 121 121 LEU LEU A . n 
A 1 124 PRO 124 122 122 PRO PRO A . n 
A 1 125 GLU 125 123 123 GLU GLU A . n 
A 1 126 ASP 126 124 124 ASP ASP A . n 
A 1 127 ALA 127 125 125 ALA ALA A . n 
A 1 128 THR 128 126 126 THR THR A . n 
A 1 129 GLY 129 127 127 GLY GLY A . n 
A 1 130 LEU 130 128 128 LEU LEU A . n 
A 1 131 ASP 131 129 129 ASP ASP A . n 
A 1 132 SER 132 130 130 SER SER A . n 
A 1 133 PRO 133 131 131 PRO PRO A . n 
A 1 134 GLY 134 132 132 GLY GLY A . n 
A 1 135 TYR 135 133 133 TYR TYR A . n 
A 1 136 ARG 136 134 134 ARG ARG A . n 
A 1 137 ASN 137 135 135 ASN ASN A . n 
A 1 138 LEU 138 136 136 LEU LEU A . n 
A 1 139 ARG 139 137 137 ARG ARG A . n 
A 1 140 ARG 140 138 138 ARG ARG A . n 
A 1 141 VAL 141 139 139 VAL VAL A . n 
A 1 142 ALA 142 140 140 ALA ALA A . n 
A 1 143 ARG 143 141 141 ARG ARG A . n 
A 1 144 PRO 144 142 142 PRO PRO A . n 
A 1 145 VAL 145 143 143 VAL VAL A . n 
A 1 146 TRP 146 144 144 TRP TRP A . n 
A 1 147 LYS 147 145 145 LYS LYS A . n 
A 1 148 ALA 148 146 146 ALA ALA A . n 
A 1 149 TYR 149 147 147 TYR TYR A . n 
A 1 150 GLU 150 148 148 GLU GLU A . n 
A 1 151 GLN 151 149 149 GLN GLN A . n 
A 1 152 ALA 152 150 150 ALA ALA A . n 
A 1 153 VAL 153 151 151 VAL VAL A . n 
A 1 154 GLU 154 152 152 GLU GLU A . n 
A 1 155 ARG 155 153 153 ARG ARG A . n 
A 1 156 ALA 156 154 154 ALA ALA A . n 
A 1 157 GLY 157 155 155 GLY GLY A . n 
A 1 158 LEU 158 156 156 LEU LEU A . n 
A 1 159 SER 159 157 157 SER SER A . n 
A 1 160 LEU 160 158 158 LEU LEU A . n 
A 1 161 GLN 161 159 159 GLN GLN A . n 
A 1 162 ASP 162 160 160 ASP ASP A . n 
A 1 163 VAL 163 161 161 VAL VAL A . n 
A 1 164 ILE 164 162 162 ILE ILE A . n 
A 1 165 ALA 165 163 163 ALA ALA A . n 
A 1 166 GLN 166 164 164 GLN GLN A . n 
A 1 167 GLN 167 165 165 GLN GLN A . n 
A 1 168 ASP 168 166 166 ASP ASP A . n 
A 1 169 ASP 169 167 167 ASP ASP A . n 
A 1 170 GLY 170 168 168 GLY GLY A . n 
A 1 171 TYR 171 169 169 TYR TYR A . n 
A 1 172 ASP 172 170 170 ASP ASP A . n 
A 1 173 GLY 173 171 171 GLY GLY A . n 
A 1 174 PRO 174 172 172 PRO PRO A . n 
A 1 175 ARG 175 173 173 ARG ARG A . n 
A 1 176 SER 176 174 174 SER SER A . n 
A 1 177 GLY 177 175 175 GLY GLY A . n 
A 1 178 GLY 178 176 176 GLY GLY A . n 
A 1 179 SER 179 177 177 SER SER A . n 
A 1 180 GLN 180 178 178 GLN GLN A . n 
A 1 181 SER 181 179 179 SER SER A . n 
A 1 182 LEU 182 180 180 LEU LEU A . n 
A 1 183 ALA 183 181 181 ALA ALA A . n 
A 1 184 LEU 184 182 182 LEU LEU A . n 
A 1 185 VAL 185 183 183 VAL VAL A . n 
A 1 186 ARG 186 184 184 ARG ARG A . n 
A 1 187 GLU 187 185 185 GLU GLU A . n 
A 1 188 ALA 188 186 186 ALA ALA A . n 
A 1 189 MET 189 187 187 MET MET A . n 
A 1 190 LEU 190 188 188 LEU LEU A . n 
A 1 191 ARG 191 189 189 ARG ARG A . n 
A 1 192 LEU 192 190 190 LEU LEU A . n 
A 1 193 ASP 193 191 191 ASP ASP A . n 
A 1 194 GLY 194 192 192 GLY GLY A . n 
A 1 195 SER 195 193 193 SER SER A . n 
A 1 196 VAL 196 194 194 VAL VAL A . n 
A 1 197 LEU 197 195 195 LEU LEU A . n 
A 1 198 GLY 198 196 196 GLY GLY A . n 
A 1 199 TRP 199 197 197 TRP TRP A . n 
A 1 200 LYS 200 198 198 LYS LYS A . n 
A 1 201 GLN 201 199 199 GLN GLN A . n 
A 1 202 HIS 202 200 200 HIS HIS A . n 
A 1 203 HIS 203 201 201 HIS HIS A . n 
A 1 204 LEU 204 202 202 LEU LEU A . n 
A 1 205 ILE 205 203 203 ILE ILE A . n 
A 1 206 MET 206 204 204 MET MET A . n 
A 1 207 VAL 207 205 205 VAL VAL A . n 
A 1 208 TRP 208 206 206 TRP TRP A . n 
A 1 209 SER 209 207 207 SER SER A . n 
A 1 210 GLN 210 208 208 GLN GLN A . n 
A 1 211 LEU 211 209 209 LEU LEU A . n 
A 1 212 GLY 212 210 210 GLY GLY A . n 
A 1 213 GLY 213 211 211 GLY GLY A . n 
A 1 214 GLN 214 212 212 GLN GLN A . n 
A 1 215 PRO 215 213 213 PRO PRO A . n 
A 1 216 GLY 216 214 214 GLY GLY A . n 
A 1 217 LEU 217 215 215 LEU LEU A . n 
A 1 218 ARG 218 216 216 ARG ARG A . n 
A 1 219 LYS 219 217 ?   ?   ?   A . n 
A 1 220 GLY 220 218 ?   ?   ?   A . n 
A 1 221 ASN 221 219 ?   ?   ?   A . n 
A 1 222 GLU 222 220 ?   ?   ?   A . n 
A 1 223 GLU 223 221 ?   ?   ?   A . n 
A 1 224 GLY 224 222 ?   ?   ?   A . n 
A 1 225 ASP 225 223 ?   ?   ?   A . n 
A 1 226 ASP 226 224 ?   ?   ?   A . n 
A 1 227 GLY 227 225 ?   ?   ?   A . n 
A 1 228 LEU 228 226 ?   ?   ?   A . n 
A 1 229 GLU 229 227 227 GLU GLU A . n 
A 1 230 LEU 230 228 228 LEU LEU A . n 
A 1 231 PRO 231 229 229 PRO PRO A . n 
A 1 232 GLN 232 230 230 GLN GLN A . n 
A 1 233 SER 233 231 231 SER SER A . n 
A 1 234 LEU 234 232 232 LEU LEU A . n 
A 1 235 GLY 235 233 233 GLY GLY A . n 
A 1 236 GLY 236 234 234 GLY GLY A . n 
A 1 237 ARG 237 235 235 ARG ARG A . n 
A 1 238 SER 238 236 236 SER SER A . n 
A 1 239 LEU 239 237 237 LEU LEU A . n 
A 1 240 ALA 240 238 238 ALA ALA A . n 
A 1 241 THR 241 239 239 THR THR A . n 
A 1 242 LEU 242 240 240 LEU LEU A . n 
A 1 243 GLU 243 241 241 GLU GLU A . n 
A 1 244 ALA 244 242 242 ALA ALA A . n 
A 1 245 ARG 245 243 243 ARG ARG A . n 
A 1 246 SER 246 244 244 SER SER A . n 
A 1 247 GLN 247 245 245 GLN GLN A . n 
A 1 248 LEU 248 246 246 LEU LEU A . n 
A 1 249 ALA 249 247 247 ALA ALA A . n 
A 1 250 LEU 250 248 248 LEU LEU A . n 
A 1 251 PHE 251 249 249 PHE PHE A . n 
A 1 252 PRO 252 250 250 PRO PRO A . n 
A 1 253 GLU 253 251 251 GLU GLU A . n 
A 1 254 LEU 254 252 252 LEU LEU A . n 
A 1 255 TRP 255 253 253 TRP TRP A . n 
A 1 256 ARG 256 254 254 ARG ARG A . n 
A 1 257 ALA 257 255 255 ALA ALA A . n 
A 1 258 ALA 258 256 256 ALA ALA A . n 
A 1 259 GLU 259 257 257 GLU GLU A . n 
A 1 260 ASP 260 258 258 ASP ASP A . n 
A 1 261 ALA 261 259 259 ALA ALA A . n 
A 1 262 TYR 262 260 260 TYR TYR A . n 
A 1 263 TRP 263 261 261 TRP TRP A . n 
A 1 264 LEU 264 262 262 LEU LEU A . n 
A 1 265 LEU 265 263 263 LEU LEU A . n 
A 1 266 GLY 266 264 264 GLY GLY A . n 
A 1 267 THR 267 265 265 THR THR A . n 
A 1 268 ARG 268 266 ?   ?   ?   A . n 
A 1 269 HIS 269 267 ?   ?   ?   A . n 
A 1 270 ASP 270 268 ?   ?   ?   A . n 
A 1 271 THR 271 269 ?   ?   ?   A . n 
A 1 272 ASP 272 270 ?   ?   ?   A . n 
A 1 273 ALA 273 271 ?   ?   ?   A . n 
A 1 274 PRO 274 272 ?   ?   ?   A . n 
A 1 275 VAL 275 273 ?   ?   ?   A . n 
A 1 276 ARG 276 274 ?   ?   ?   A . n 
A 1 277 GLY 277 275 ?   ?   ?   A . n 
A 1 278 GLY 278 276 ?   ?   ?   A . n 
A 1 279 GLY 279 277 ?   ?   ?   A . n 
A 1 280 ASN 280 278 ?   ?   ?   A . n 
A 1 281 GLY 281 279 ?   ?   ?   A . n 
A 1 282 SER 282 280 ?   ?   ?   A . n 
A 1 283 PRO 283 281 ?   ?   ?   A . n 
A 1 284 VAL 284 282 ?   ?   ?   A . n 
A 1 285 GLN 285 283 ?   ?   ?   A . n 
A 1 286 HIS 286 284 ?   ?   ?   A . n 
B 1 1   GLY 1   -1  ?   ?   ?   B . n 
B 1 2   HIS 2   0   ?   ?   ?   B . n 
B 1 3   MET 3   1   ?   ?   ?   B . n 
B 1 4   LYS 4   2   2   LYS LYS B . n 
B 1 5   ARG 5   3   3   ARG ARG B . n 
B 1 6   SER 6   4   4   SER SER B . n 
B 1 7   LEU 7   5   5   LEU LEU B . n 
B 1 8   ASN 8   6   6   ASN ASN B . n 
B 1 9   PRO 9   7   7   PRO PRO B . n 
B 1 10  ASP 10  8   8   ASP ASP B . n 
B 1 11  GLU 11  9   9   GLU GLU B . n 
B 1 12  PRO 12  10  10  PRO PRO B . n 
B 1 13  ASN 13  11  11  ASN ASN B . n 
B 1 14  ALA 14  12  12  ALA ALA B . n 
B 1 15  LEU 15  13  13  LEU LEU B . n 
B 1 16  LEU 16  14  14  LEU LEU B . n 
B 1 17  SER 17  15  15  SER SER B . n 
B 1 18  TYR 18  16  16  TYR TYR B . n 
B 1 19  ASP 19  17  17  ASP ASP B . n 
B 1 20  PHE 20  18  18  PHE PHE B . n 
B 1 21  ASP 21  19  19  ASP ASP B . n 
B 1 22  ARG 22  20  20  ARG ARG B . n 
B 1 23  GLY 23  21  21  GLY GLY B . n 
B 1 24  SER 24  22  22  SER SER B . n 
B 1 25  ASN 25  23  23  ASN ASN B . n 
B 1 26  TYR 26  24  24  TYR TYR B . n 
B 1 27  GLU 27  25  25  GLU GLU B . n 
B 1 28  ASN 28  26  26  ASN ASN B . n 
B 1 29  VAL 29  27  27  VAL VAL B . n 
B 1 30  LEU 30  28  28  LEU LEU B . n 
B 1 31  HIS 31  29  29  HIS HIS B . n 
B 1 32  LEU 32  30  30  LEU LEU B . n 
B 1 33  THR 33  31  31  THR THR B . n 
B 1 34  ASP 34  32  32  ASP ASP B . n 
B 1 35  ALA 35  33  33  ALA ALA B . n 
B 1 36  LEU 36  34  34  LEU LEU B . n 
B 1 37  GLY 37  35  35  GLY GLY B . n 
B 1 38  ALA 38  36  36  ALA ALA B . n 
B 1 39  LEU 39  37  37  LEU LEU B . n 
B 1 40  VAL 40  38  38  VAL VAL B . n 
B 1 41  PRO 41  39  39  PRO PRO B . n 
B 1 42  GLU 42  40  40  GLU GLU B . n 
B 1 43  SER 43  41  41  SER SER B . n 
B 1 44  GLU 44  42  42  GLU GLU B . n 
B 1 45  THR 45  43  43  THR THR B . n 
B 1 46  GLU 46  44  44  GLU GLU B . n 
B 1 47  HIS 47  45  45  HIS HIS B . n 
B 1 48  PRO 48  46  46  PRO PRO B . n 
B 1 49  ASP 49  47  47  ASP ASP B . n 
B 1 50  GLN 50  48  48  GLN GLN B . n 
B 1 51  ARG 51  49  49  ARG ARG B . n 
B 1 52  PHE 52  50  50  PHE PHE B . n 
B 1 53  PHE 53  51  51  PHE PHE B . n 
B 1 54  GLN 54  52  52  GLN GLN B . n 
B 1 55  VAL 55  53  53  VAL VAL B . n 
B 1 56  THR 56  54  54  THR THR B . n 
B 1 57  HIS 57  55  55  HIS HIS B . n 
B 1 58  LEU 58  56  56  LEU LEU B . n 
B 1 59  ILE 59  57  57  ILE ILE B . n 
B 1 60  THR 60  58  58  THR THR B . n 
B 1 61  GLU 61  59  59  GLU GLU B . n 
B 1 62  TYR 62  60  60  TYR TYR B . n 
B 1 63  ALA 63  61  61  ALA ALA B . n 
B 1 64  TRP 64  62  62  TRP TRP B . n 
B 1 65  VAL 65  63  63  VAL VAL B . n 
B 1 66  GLN 66  64  64  GLN GLN B . n 
B 1 67  VAL 67  65  65  VAL VAL B . n 
B 1 68  HIS 68  66  66  HIS HIS B . n 
B 1 69  TYR 69  67  67  TYR TYR B . n 
B 1 70  GLU 70  68  68  GLU GLU B . n 
B 1 71  LEU 71  69  69  LEU LEU B . n 
B 1 72  ARG 72  70  70  ARG ARG B . n 
B 1 73  ARG 73  71  71  ARG ARG B . n 
B 1 74  ALA 74  72  72  ALA ALA B . n 
B 1 75  ILE 75  73  73  ILE ILE B . n 
B 1 76  GLY 76  74  74  GLY GLY B . n 
B 1 77  HIS 77  75  75  HIS HIS B . n 
B 1 78  LEU 78  76  76  LEU LEU B . n 
B 1 79  ASP 79  77  77  ASP ASP B . n 
B 1 80  GLU 80  78  78  GLU GLU B . n 
B 1 81  ASP 81  79  79  ASP ASP B . n 
B 1 82  ARG 82  80  80  ARG ARG B . n 
B 1 83  TYR 83  81  81  TYR TYR B . n 
B 1 84  HIS 84  82  82  HIS HIS B . n 
B 1 85  GLN 85  83  83  GLN GLN B . n 
B 1 86  ALA 86  84  84  ALA ALA B . n 
B 1 87  VAL 87  85  85  VAL VAL B . n 
B 1 88  ARG 88  86  86  ARG ARG B . n 
B 1 89  MET 89  87  87  MET MET B . n 
B 1 90  PHE 90  88  88  PHE PHE B . n 
B 1 91  ASP 91  89  89  ASP ASP B . n 
B 1 92  ARG 92  90  90  ARG ARG B . n 
B 1 93  ALA 93  91  91  ALA ALA B . n 
B 1 94  THR 94  92  92  THR THR B . n 
B 1 95  GLY 95  93  93  GLY GLY B . n 
B 1 96  LEU 96  94  94  LEU LEU B . n 
B 1 97  SER 97  95  95  SER SER B . n 
B 1 98  GLU 98  96  96  GLU GLU B . n 
B 1 99  VAL 99  97  97  VAL VAL B . n 
B 1 100 THR 100 98  98  THR THR B . n 
B 1 101 VAL 101 99  99  VAL VAL B . n 
B 1 102 GLN 102 100 100 GLN GLN B . n 
B 1 103 ALA 103 101 101 ALA ALA B . n 
B 1 104 VAL 104 102 102 VAL VAL B . n 
B 1 105 ARG 105 103 103 ARG ARG B . n 
B 1 106 LEU 106 104 104 LEU LEU B . n 
B 1 107 LEU 107 105 105 LEU LEU B . n 
B 1 108 THR 108 106 106 THR THR B . n 
B 1 109 ASP 109 107 107 ASP ASP B . n 
B 1 110 HIS 110 108 108 HIS HIS B . n 
B 1 111 LEU 111 109 109 LEU LEU B . n 
B 1 112 PRO 112 110 110 PRO PRO B . n 
B 1 113 GLN 113 111 111 GLN GLN B . n 
B 1 114 HIS 114 112 112 HIS HIS B . n 
B 1 115 SER 115 113 113 SER SER B . n 
B 1 116 LEU 116 114 114 LEU LEU B . n 
B 1 117 LEU 117 115 115 LEU LEU B . n 
B 1 118 MET 118 116 116 MET MET B . n 
B 1 119 MET 119 117 117 MET MET B . n 
B 1 120 ARG 120 118 118 ARG ARG B . n 
B 1 121 ASN 121 119 119 ASN ASN B . n 
B 1 122 ALA 122 120 120 ALA ALA B . n 
B 1 123 LEU 123 121 121 LEU LEU B . n 
B 1 124 PRO 124 122 122 PRO PRO B . n 
B 1 125 GLU 125 123 123 GLU GLU B . n 
B 1 126 ASP 126 124 124 ASP ASP B . n 
B 1 127 ALA 127 125 125 ALA ALA B . n 
B 1 128 THR 128 126 126 THR THR B . n 
B 1 129 GLY 129 127 127 GLY GLY B . n 
B 1 130 LEU 130 128 128 LEU LEU B . n 
B 1 131 ASP 131 129 129 ASP ASP B . n 
B 1 132 SER 132 130 130 SER SER B . n 
B 1 133 PRO 133 131 131 PRO PRO B . n 
B 1 134 GLY 134 132 132 GLY GLY B . n 
B 1 135 TYR 135 133 133 TYR TYR B . n 
B 1 136 ARG 136 134 134 ARG ARG B . n 
B 1 137 ASN 137 135 135 ASN ASN B . n 
B 1 138 LEU 138 136 136 LEU LEU B . n 
B 1 139 ARG 139 137 137 ARG ARG B . n 
B 1 140 ARG 140 138 138 ARG ARG B . n 
B 1 141 VAL 141 139 139 VAL VAL B . n 
B 1 142 ALA 142 140 140 ALA ALA B . n 
B 1 143 ARG 143 141 141 ARG ARG B . n 
B 1 144 PRO 144 142 142 PRO PRO B . n 
B 1 145 VAL 145 143 143 VAL VAL B . n 
B 1 146 TRP 146 144 144 TRP TRP B . n 
B 1 147 LYS 147 145 145 LYS LYS B . n 
B 1 148 ALA 148 146 146 ALA ALA B . n 
B 1 149 TYR 149 147 147 TYR TYR B . n 
B 1 150 GLU 150 148 148 GLU GLU B . n 
B 1 151 GLN 151 149 149 GLN GLN B . n 
B 1 152 ALA 152 150 150 ALA ALA B . n 
B 1 153 VAL 153 151 151 VAL VAL B . n 
B 1 154 GLU 154 152 152 GLU GLU B . n 
B 1 155 ARG 155 153 153 ARG ARG B . n 
B 1 156 ALA 156 154 154 ALA ALA B . n 
B 1 157 GLY 157 155 155 GLY GLY B . n 
B 1 158 LEU 158 156 156 LEU LEU B . n 
B 1 159 SER 159 157 157 SER SER B . n 
B 1 160 LEU 160 158 158 LEU LEU B . n 
B 1 161 GLN 161 159 159 GLN GLN B . n 
B 1 162 ASP 162 160 160 ASP ASP B . n 
B 1 163 VAL 163 161 161 VAL VAL B . n 
B 1 164 ILE 164 162 162 ILE ILE B . n 
B 1 165 ALA 165 163 163 ALA ALA B . n 
B 1 166 GLN 166 164 164 GLN GLN B . n 
B 1 167 GLN 167 165 165 GLN GLN B . n 
B 1 168 ASP 168 166 166 ASP ASP B . n 
B 1 169 ASP 169 167 167 ASP ASP B . n 
B 1 170 GLY 170 168 168 GLY GLY B . n 
B 1 171 TYR 171 169 169 TYR TYR B . n 
B 1 172 ASP 172 170 170 ASP ASP B . n 
B 1 173 GLY 173 171 171 GLY GLY B . n 
B 1 174 PRO 174 172 172 PRO PRO B . n 
B 1 175 ARG 175 173 173 ARG ARG B . n 
B 1 176 SER 176 174 174 SER SER B . n 
B 1 177 GLY 177 175 175 GLY GLY B . n 
B 1 178 GLY 178 176 176 GLY GLY B . n 
B 1 179 SER 179 177 177 SER SER B . n 
B 1 180 GLN 180 178 178 GLN GLN B . n 
B 1 181 SER 181 179 179 SER SER B . n 
B 1 182 LEU 182 180 180 LEU LEU B . n 
B 1 183 ALA 183 181 181 ALA ALA B . n 
B 1 184 LEU 184 182 182 LEU LEU B . n 
B 1 185 VAL 185 183 183 VAL VAL B . n 
B 1 186 ARG 186 184 184 ARG ARG B . n 
B 1 187 GLU 187 185 185 GLU GLU B . n 
B 1 188 ALA 188 186 186 ALA ALA B . n 
B 1 189 MET 189 187 187 MET MET B . n 
B 1 190 LEU 190 188 188 LEU LEU B . n 
B 1 191 ARG 191 189 189 ARG ARG B . n 
B 1 192 LEU 192 190 190 LEU LEU B . n 
B 1 193 ASP 193 191 191 ASP ASP B . n 
B 1 194 GLY 194 192 192 GLY GLY B . n 
B 1 195 SER 195 193 193 SER SER B . n 
B 1 196 VAL 196 194 194 VAL VAL B . n 
B 1 197 LEU 197 195 195 LEU LEU B . n 
B 1 198 GLY 198 196 196 GLY GLY B . n 
B 1 199 TRP 199 197 197 TRP TRP B . n 
B 1 200 LYS 200 198 198 LYS LYS B . n 
B 1 201 GLN 201 199 199 GLN GLN B . n 
B 1 202 HIS 202 200 200 HIS HIS B . n 
B 1 203 HIS 203 201 201 HIS HIS B . n 
B 1 204 LEU 204 202 202 LEU LEU B . n 
B 1 205 ILE 205 203 203 ILE ILE B . n 
B 1 206 MET 206 204 204 MET MET B . n 
B 1 207 VAL 207 205 205 VAL VAL B . n 
B 1 208 TRP 208 206 206 TRP TRP B . n 
B 1 209 SER 209 207 207 SER SER B . n 
B 1 210 GLN 210 208 208 GLN GLN B . n 
B 1 211 LEU 211 209 209 LEU LEU B . n 
B 1 212 GLY 212 210 210 GLY GLY B . n 
B 1 213 GLY 213 211 211 GLY GLY B . n 
B 1 214 GLN 214 212 212 GLN GLN B . n 
B 1 215 PRO 215 213 213 PRO PRO B . n 
B 1 216 GLY 216 214 214 GLY GLY B . n 
B 1 217 LEU 217 215 215 LEU LEU B . n 
B 1 218 ARG 218 216 ?   ?   ?   B . n 
B 1 219 LYS 219 217 ?   ?   ?   B . n 
B 1 220 GLY 220 218 ?   ?   ?   B . n 
B 1 221 ASN 221 219 ?   ?   ?   B . n 
B 1 222 GLU 222 220 ?   ?   ?   B . n 
B 1 223 GLU 223 221 ?   ?   ?   B . n 
B 1 224 GLY 224 222 ?   ?   ?   B . n 
B 1 225 ASP 225 223 ?   ?   ?   B . n 
B 1 226 ASP 226 224 ?   ?   ?   B . n 
B 1 227 GLY 227 225 ?   ?   ?   B . n 
B 1 228 LEU 228 226 ?   ?   ?   B . n 
B 1 229 GLU 229 227 ?   ?   ?   B . n 
B 1 230 LEU 230 228 228 LEU LEU B . n 
B 1 231 PRO 231 229 229 PRO PRO B . n 
B 1 232 GLN 232 230 230 GLN GLN B . n 
B 1 233 SER 233 231 231 SER SER B . n 
B 1 234 LEU 234 232 232 LEU LEU B . n 
B 1 235 GLY 235 233 233 GLY GLY B . n 
B 1 236 GLY 236 234 234 GLY GLY B . n 
B 1 237 ARG 237 235 235 ARG ARG B . n 
B 1 238 SER 238 236 236 SER SER B . n 
B 1 239 LEU 239 237 237 LEU LEU B . n 
B 1 240 ALA 240 238 238 ALA ALA B . n 
B 1 241 THR 241 239 239 THR THR B . n 
B 1 242 LEU 242 240 240 LEU LEU B . n 
B 1 243 GLU 243 241 241 GLU GLU B . n 
B 1 244 ALA 244 242 242 ALA ALA B . n 
B 1 245 ARG 245 243 243 ARG ARG B . n 
B 1 246 SER 246 244 244 SER SER B . n 
B 1 247 GLN 247 245 245 GLN GLN B . n 
B 1 248 LEU 248 246 246 LEU LEU B . n 
B 1 249 ALA 249 247 247 ALA ALA B . n 
B 1 250 LEU 250 248 248 LEU LEU B . n 
B 1 251 PHE 251 249 249 PHE PHE B . n 
B 1 252 PRO 252 250 250 PRO PRO B . n 
B 1 253 GLU 253 251 251 GLU GLU B . n 
B 1 254 LEU 254 252 252 LEU LEU B . n 
B 1 255 TRP 255 253 253 TRP TRP B . n 
B 1 256 ARG 256 254 254 ARG ARG B . n 
B 1 257 ALA 257 255 255 ALA ALA B . n 
B 1 258 ALA 258 256 256 ALA ALA B . n 
B 1 259 GLU 259 257 257 GLU GLU B . n 
B 1 260 ASP 260 258 258 ASP ASP B . n 
B 1 261 ALA 261 259 259 ALA ALA B . n 
B 1 262 TYR 262 260 260 TYR TYR B . n 
B 1 263 TRP 263 261 261 TRP TRP B . n 
B 1 264 LEU 264 262 262 LEU LEU B . n 
B 1 265 LEU 265 263 263 LEU LEU B . n 
B 1 266 GLY 266 264 264 GLY GLY B . n 
B 1 267 THR 267 265 265 THR THR B . n 
B 1 268 ARG 268 266 266 ARG ARG B . n 
B 1 269 HIS 269 267 267 HIS HIS B . n 
B 1 270 ASP 270 268 268 ASP ASP B . n 
B 1 271 THR 271 269 269 THR THR B . n 
B 1 272 ASP 272 270 270 ASP ASP B . n 
B 1 273 ALA 273 271 271 ALA ALA B . n 
B 1 274 PRO 274 272 272 PRO PRO B . n 
B 1 275 VAL 275 273 273 VAL VAL B . n 
B 1 276 ARG 276 274 ?   ?   ?   B . n 
B 1 277 GLY 277 275 ?   ?   ?   B . n 
B 1 278 GLY 278 276 ?   ?   ?   B . n 
B 1 279 GLY 279 277 ?   ?   ?   B . n 
B 1 280 ASN 280 278 ?   ?   ?   B . n 
B 1 281 GLY 281 279 ?   ?   ?   B . n 
B 1 282 SER 282 280 ?   ?   ?   B . n 
B 1 283 PRO 283 281 ?   ?   ?   B . n 
B 1 284 VAL 284 282 ?   ?   ?   B . n 
B 1 285 GLN 285 283 ?   ?   ?   B . n 
B 1 286 HIS 286 284 ?   ?   ?   B . n 
C 1 1   GLY 1   -1  ?   ?   ?   C . n 
C 1 2   HIS 2   0   ?   ?   ?   C . n 
C 1 3   MET 3   1   ?   ?   ?   C . n 
C 1 4   LYS 4   2   2   LYS LYS C . n 
C 1 5   ARG 5   3   3   ARG ARG C . n 
C 1 6   SER 6   4   4   SER SER C . n 
C 1 7   LEU 7   5   5   LEU LEU C . n 
C 1 8   ASN 8   6   6   ASN ASN C . n 
C 1 9   PRO 9   7   7   PRO PRO C . n 
C 1 10  ASP 10  8   8   ASP ASP C . n 
C 1 11  GLU 11  9   9   GLU GLU C . n 
C 1 12  PRO 12  10  10  PRO PRO C . n 
C 1 13  ASN 13  11  11  ASN ASN C . n 
C 1 14  ALA 14  12  12  ALA ALA C . n 
C 1 15  LEU 15  13  13  LEU LEU C . n 
C 1 16  LEU 16  14  14  LEU LEU C . n 
C 1 17  SER 17  15  15  SER SER C . n 
C 1 18  TYR 18  16  16  TYR TYR C . n 
C 1 19  ASP 19  17  17  ASP ASP C . n 
C 1 20  PHE 20  18  18  PHE PHE C . n 
C 1 21  ASP 21  19  19  ASP ASP C . n 
C 1 22  ARG 22  20  20  ARG ARG C . n 
C 1 23  GLY 23  21  21  GLY GLY C . n 
C 1 24  SER 24  22  22  SER SER C . n 
C 1 25  ASN 25  23  23  ASN ASN C . n 
C 1 26  TYR 26  24  24  TYR TYR C . n 
C 1 27  GLU 27  25  25  GLU GLU C . n 
C 1 28  ASN 28  26  26  ASN ASN C . n 
C 1 29  VAL 29  27  27  VAL VAL C . n 
C 1 30  LEU 30  28  28  LEU LEU C . n 
C 1 31  HIS 31  29  29  HIS HIS C . n 
C 1 32  LEU 32  30  30  LEU LEU C . n 
C 1 33  THR 33  31  31  THR THR C . n 
C 1 34  ASP 34  32  32  ASP ASP C . n 
C 1 35  ALA 35  33  33  ALA ALA C . n 
C 1 36  LEU 36  34  34  LEU LEU C . n 
C 1 37  GLY 37  35  35  GLY GLY C . n 
C 1 38  ALA 38  36  36  ALA ALA C . n 
C 1 39  LEU 39  37  37  LEU LEU C . n 
C 1 40  VAL 40  38  38  VAL VAL C . n 
C 1 41  PRO 41  39  39  PRO PRO C . n 
C 1 42  GLU 42  40  40  GLU GLU C . n 
C 1 43  SER 43  41  41  SER SER C . n 
C 1 44  GLU 44  42  42  GLU GLU C . n 
C 1 45  THR 45  43  43  THR THR C . n 
C 1 46  GLU 46  44  44  GLU GLU C . n 
C 1 47  HIS 47  45  45  HIS HIS C . n 
C 1 48  PRO 48  46  46  PRO PRO C . n 
C 1 49  ASP 49  47  47  ASP ASP C . n 
C 1 50  GLN 50  48  48  GLN GLN C . n 
C 1 51  ARG 51  49  49  ARG ARG C . n 
C 1 52  PHE 52  50  50  PHE PHE C . n 
C 1 53  PHE 53  51  51  PHE PHE C . n 
C 1 54  GLN 54  52  52  GLN GLN C . n 
C 1 55  VAL 55  53  53  VAL VAL C . n 
C 1 56  THR 56  54  54  THR THR C . n 
C 1 57  HIS 57  55  55  HIS HIS C . n 
C 1 58  LEU 58  56  56  LEU LEU C . n 
C 1 59  ILE 59  57  57  ILE ILE C . n 
C 1 60  THR 60  58  58  THR THR C . n 
C 1 61  GLU 61  59  59  GLU GLU C . n 
C 1 62  TYR 62  60  60  TYR TYR C . n 
C 1 63  ALA 63  61  61  ALA ALA C . n 
C 1 64  TRP 64  62  62  TRP TRP C . n 
C 1 65  VAL 65  63  63  VAL VAL C . n 
C 1 66  GLN 66  64  64  GLN GLN C . n 
C 1 67  VAL 67  65  65  VAL VAL C . n 
C 1 68  HIS 68  66  66  HIS HIS C . n 
C 1 69  TYR 69  67  67  TYR TYR C . n 
C 1 70  GLU 70  68  68  GLU GLU C . n 
C 1 71  LEU 71  69  69  LEU LEU C . n 
C 1 72  ARG 72  70  70  ARG ARG C . n 
C 1 73  ARG 73  71  71  ARG ARG C . n 
C 1 74  ALA 74  72  72  ALA ALA C . n 
C 1 75  ILE 75  73  73  ILE ILE C . n 
C 1 76  GLY 76  74  74  GLY GLY C . n 
C 1 77  HIS 77  75  75  HIS HIS C . n 
C 1 78  LEU 78  76  76  LEU LEU C . n 
C 1 79  ASP 79  77  77  ASP ASP C . n 
C 1 80  GLU 80  78  78  GLU GLU C . n 
C 1 81  ASP 81  79  79  ASP ASP C . n 
C 1 82  ARG 82  80  80  ARG ARG C . n 
C 1 83  TYR 83  81  81  TYR TYR C . n 
C 1 84  HIS 84  82  82  HIS HIS C . n 
C 1 85  GLN 85  83  83  GLN GLN C . n 
C 1 86  ALA 86  84  84  ALA ALA C . n 
C 1 87  VAL 87  85  85  VAL VAL C . n 
C 1 88  ARG 88  86  86  ARG ARG C . n 
C 1 89  MET 89  87  87  MET MET C . n 
C 1 90  PHE 90  88  88  PHE PHE C . n 
C 1 91  ASP 91  89  89  ASP ASP C . n 
C 1 92  ARG 92  90  90  ARG ARG C . n 
C 1 93  ALA 93  91  91  ALA ALA C . n 
C 1 94  THR 94  92  92  THR THR C . n 
C 1 95  GLY 95  93  93  GLY GLY C . n 
C 1 96  LEU 96  94  94  LEU LEU C . n 
C 1 97  SER 97  95  95  SER SER C . n 
C 1 98  GLU 98  96  96  GLU GLU C . n 
C 1 99  VAL 99  97  97  VAL VAL C . n 
C 1 100 THR 100 98  98  THR THR C . n 
C 1 101 VAL 101 99  99  VAL VAL C . n 
C 1 102 GLN 102 100 100 GLN GLN C . n 
C 1 103 ALA 103 101 101 ALA ALA C . n 
C 1 104 VAL 104 102 102 VAL VAL C . n 
C 1 105 ARG 105 103 103 ARG ARG C . n 
C 1 106 LEU 106 104 104 LEU LEU C . n 
C 1 107 LEU 107 105 105 LEU LEU C . n 
C 1 108 THR 108 106 106 THR THR C . n 
C 1 109 ASP 109 107 107 ASP ASP C . n 
C 1 110 HIS 110 108 108 HIS HIS C . n 
C 1 111 LEU 111 109 109 LEU LEU C . n 
C 1 112 PRO 112 110 110 PRO PRO C . n 
C 1 113 GLN 113 111 111 GLN GLN C . n 
C 1 114 HIS 114 112 112 HIS HIS C . n 
C 1 115 SER 115 113 113 SER SER C . n 
C 1 116 LEU 116 114 114 LEU LEU C . n 
C 1 117 LEU 117 115 115 LEU LEU C . n 
C 1 118 MET 118 116 116 MET MET C . n 
C 1 119 MET 119 117 117 MET MET C . n 
C 1 120 ARG 120 118 118 ARG ARG C . n 
C 1 121 ASN 121 119 119 ASN ASN C . n 
C 1 122 ALA 122 120 120 ALA ALA C . n 
C 1 123 LEU 123 121 121 LEU LEU C . n 
C 1 124 PRO 124 122 122 PRO PRO C . n 
C 1 125 GLU 125 123 123 GLU GLU C . n 
C 1 126 ASP 126 124 124 ASP ASP C . n 
C 1 127 ALA 127 125 125 ALA ALA C . n 
C 1 128 THR 128 126 126 THR THR C . n 
C 1 129 GLY 129 127 127 GLY GLY C . n 
C 1 130 LEU 130 128 128 LEU LEU C . n 
C 1 131 ASP 131 129 129 ASP ASP C . n 
C 1 132 SER 132 130 130 SER SER C . n 
C 1 133 PRO 133 131 131 PRO PRO C . n 
C 1 134 GLY 134 132 132 GLY GLY C . n 
C 1 135 TYR 135 133 133 TYR TYR C . n 
C 1 136 ARG 136 134 134 ARG ARG C . n 
C 1 137 ASN 137 135 135 ASN ASN C . n 
C 1 138 LEU 138 136 136 LEU LEU C . n 
C 1 139 ARG 139 137 137 ARG ARG C . n 
C 1 140 ARG 140 138 138 ARG ARG C . n 
C 1 141 VAL 141 139 139 VAL VAL C . n 
C 1 142 ALA 142 140 140 ALA ALA C . n 
C 1 143 ARG 143 141 141 ARG ARG C . n 
C 1 144 PRO 144 142 142 PRO PRO C . n 
C 1 145 VAL 145 143 143 VAL VAL C . n 
C 1 146 TRP 146 144 144 TRP TRP C . n 
C 1 147 LYS 147 145 145 LYS LYS C . n 
C 1 148 ALA 148 146 146 ALA ALA C . n 
C 1 149 TYR 149 147 147 TYR TYR C . n 
C 1 150 GLU 150 148 148 GLU GLU C . n 
C 1 151 GLN 151 149 149 GLN GLN C . n 
C 1 152 ALA 152 150 150 ALA ALA C . n 
C 1 153 VAL 153 151 151 VAL VAL C . n 
C 1 154 GLU 154 152 152 GLU GLU C . n 
C 1 155 ARG 155 153 153 ARG ARG C . n 
C 1 156 ALA 156 154 154 ALA ALA C . n 
C 1 157 GLY 157 155 155 GLY GLY C . n 
C 1 158 LEU 158 156 156 LEU LEU C . n 
C 1 159 SER 159 157 157 SER SER C . n 
C 1 160 LEU 160 158 158 LEU LEU C . n 
C 1 161 GLN 161 159 159 GLN GLN C . n 
C 1 162 ASP 162 160 160 ASP ASP C . n 
C 1 163 VAL 163 161 161 VAL VAL C . n 
C 1 164 ILE 164 162 162 ILE ILE C . n 
C 1 165 ALA 165 163 163 ALA ALA C . n 
C 1 166 GLN 166 164 164 GLN GLN C . n 
C 1 167 GLN 167 165 165 GLN GLN C . n 
C 1 168 ASP 168 166 166 ASP ASP C . n 
C 1 169 ASP 169 167 167 ASP ASP C . n 
C 1 170 GLY 170 168 168 GLY GLY C . n 
C 1 171 TYR 171 169 169 TYR TYR C . n 
C 1 172 ASP 172 170 170 ASP ASP C . n 
C 1 173 GLY 173 171 171 GLY GLY C . n 
C 1 174 PRO 174 172 172 PRO PRO C . n 
C 1 175 ARG 175 173 173 ARG ARG C . n 
C 1 176 SER 176 174 174 SER SER C . n 
C 1 177 GLY 177 175 175 GLY GLY C . n 
C 1 178 GLY 178 176 176 GLY GLY C . n 
C 1 179 SER 179 177 177 SER SER C . n 
C 1 180 GLN 180 178 178 GLN GLN C . n 
C 1 181 SER 181 179 179 SER SER C . n 
C 1 182 LEU 182 180 180 LEU LEU C . n 
C 1 183 ALA 183 181 181 ALA ALA C . n 
C 1 184 LEU 184 182 182 LEU LEU C . n 
C 1 185 VAL 185 183 183 VAL VAL C . n 
C 1 186 ARG 186 184 184 ARG ARG C . n 
C 1 187 GLU 187 185 185 GLU GLU C . n 
C 1 188 ALA 188 186 186 ALA ALA C . n 
C 1 189 MET 189 187 187 MET MET C . n 
C 1 190 LEU 190 188 188 LEU LEU C . n 
C 1 191 ARG 191 189 189 ARG ARG C . n 
C 1 192 LEU 192 190 190 LEU LEU C . n 
C 1 193 ASP 193 191 191 ASP ASP C . n 
C 1 194 GLY 194 192 192 GLY GLY C . n 
C 1 195 SER 195 193 193 SER SER C . n 
C 1 196 VAL 196 194 194 VAL VAL C . n 
C 1 197 LEU 197 195 195 LEU LEU C . n 
C 1 198 GLY 198 196 196 GLY GLY C . n 
C 1 199 TRP 199 197 197 TRP TRP C . n 
C 1 200 LYS 200 198 198 LYS LYS C . n 
C 1 201 GLN 201 199 199 GLN GLN C . n 
C 1 202 HIS 202 200 200 HIS HIS C . n 
C 1 203 HIS 203 201 201 HIS HIS C . n 
C 1 204 LEU 204 202 202 LEU LEU C . n 
C 1 205 ILE 205 203 203 ILE ILE C . n 
C 1 206 MET 206 204 204 MET MET C . n 
C 1 207 VAL 207 205 205 VAL VAL C . n 
C 1 208 TRP 208 206 206 TRP TRP C . n 
C 1 209 SER 209 207 207 SER SER C . n 
C 1 210 GLN 210 208 208 GLN GLN C . n 
C 1 211 LEU 211 209 209 LEU LEU C . n 
C 1 212 GLY 212 210 210 GLY GLY C . n 
C 1 213 GLY 213 211 211 GLY GLY C . n 
C 1 214 GLN 214 212 212 GLN GLN C . n 
C 1 215 PRO 215 213 213 PRO PRO C . n 
C 1 216 GLY 216 214 214 GLY GLY C . n 
C 1 217 LEU 217 215 215 LEU LEU C . n 
C 1 218 ARG 218 216 216 ARG ARG C . n 
C 1 219 LYS 219 217 ?   ?   ?   C . n 
C 1 220 GLY 220 218 ?   ?   ?   C . n 
C 1 221 ASN 221 219 ?   ?   ?   C . n 
C 1 222 GLU 222 220 ?   ?   ?   C . n 
C 1 223 GLU 223 221 ?   ?   ?   C . n 
C 1 224 GLY 224 222 ?   ?   ?   C . n 
C 1 225 ASP 225 223 ?   ?   ?   C . n 
C 1 226 ASP 226 224 ?   ?   ?   C . n 
C 1 227 GLY 227 225 ?   ?   ?   C . n 
C 1 228 LEU 228 226 ?   ?   ?   C . n 
C 1 229 GLU 229 227 ?   ?   ?   C . n 
C 1 230 LEU 230 228 228 LEU LEU C . n 
C 1 231 PRO 231 229 229 PRO PRO C . n 
C 1 232 GLN 232 230 230 GLN GLN C . n 
C 1 233 SER 233 231 231 SER SER C . n 
C 1 234 LEU 234 232 232 LEU LEU C . n 
C 1 235 GLY 235 233 233 GLY GLY C . n 
C 1 236 GLY 236 234 234 GLY GLY C . n 
C 1 237 ARG 237 235 235 ARG ARG C . n 
C 1 238 SER 238 236 236 SER SER C . n 
C 1 239 LEU 239 237 237 LEU LEU C . n 
C 1 240 ALA 240 238 238 ALA ALA C . n 
C 1 241 THR 241 239 239 THR THR C . n 
C 1 242 LEU 242 240 240 LEU LEU C . n 
C 1 243 GLU 243 241 241 GLU GLU C . n 
C 1 244 ALA 244 242 242 ALA ALA C . n 
C 1 245 ARG 245 243 243 ARG ARG C . n 
C 1 246 SER 246 244 244 SER SER C . n 
C 1 247 GLN 247 245 245 GLN GLN C . n 
C 1 248 LEU 248 246 246 LEU LEU C . n 
C 1 249 ALA 249 247 247 ALA ALA C . n 
C 1 250 LEU 250 248 248 LEU LEU C . n 
C 1 251 PHE 251 249 249 PHE PHE C . n 
C 1 252 PRO 252 250 250 PRO PRO C . n 
C 1 253 GLU 253 251 251 GLU GLU C . n 
C 1 254 LEU 254 252 252 LEU LEU C . n 
C 1 255 TRP 255 253 253 TRP TRP C . n 
C 1 256 ARG 256 254 254 ARG ARG C . n 
C 1 257 ALA 257 255 255 ALA ALA C . n 
C 1 258 ALA 258 256 256 ALA ALA C . n 
C 1 259 GLU 259 257 257 GLU GLU C . n 
C 1 260 ASP 260 258 258 ASP ASP C . n 
C 1 261 ALA 261 259 259 ALA ALA C . n 
C 1 262 TYR 262 260 260 TYR TYR C . n 
C 1 263 TRP 263 261 261 TRP TRP C . n 
C 1 264 LEU 264 262 262 LEU LEU C . n 
C 1 265 LEU 265 263 263 LEU LEU C . n 
C 1 266 GLY 266 264 264 GLY GLY C . n 
C 1 267 THR 267 265 265 THR THR C . n 
C 1 268 ARG 268 266 266 ARG ARG C . n 
C 1 269 HIS 269 267 267 HIS HIS C . n 
C 1 270 ASP 270 268 268 ASP ASP C . n 
C 1 271 THR 271 269 269 THR THR C . n 
C 1 272 ASP 272 270 270 ASP ASP C . n 
C 1 273 ALA 273 271 271 ALA ALA C . n 
C 1 274 PRO 274 272 272 PRO PRO C . n 
C 1 275 VAL 275 273 ?   ?   ?   C . n 
C 1 276 ARG 276 274 ?   ?   ?   C . n 
C 1 277 GLY 277 275 ?   ?   ?   C . n 
C 1 278 GLY 278 276 ?   ?   ?   C . n 
C 1 279 GLY 279 277 ?   ?   ?   C . n 
C 1 280 ASN 280 278 ?   ?   ?   C . n 
C 1 281 GLY 281 279 ?   ?   ?   C . n 
C 1 282 SER 282 280 ?   ?   ?   C . n 
C 1 283 PRO 283 281 ?   ?   ?   C . n 
C 1 284 VAL 284 282 ?   ?   ?   C . n 
C 1 285 GLN 285 283 ?   ?   ?   C . n 
C 1 286 HIS 286 284 ?   ?   ?   C . n 
D 1 1   GLY 1   -1  ?   ?   ?   D . n 
D 1 2   HIS 2   0   ?   ?   ?   D . n 
D 1 3   MET 3   1   1   MET MET D . n 
D 1 4   LYS 4   2   2   LYS LYS D . n 
D 1 5   ARG 5   3   3   ARG ARG D . n 
D 1 6   SER 6   4   4   SER SER D . n 
D 1 7   LEU 7   5   5   LEU LEU D . n 
D 1 8   ASN 8   6   6   ASN ASN D . n 
D 1 9   PRO 9   7   7   PRO PRO D . n 
D 1 10  ASP 10  8   8   ASP ASP D . n 
D 1 11  GLU 11  9   9   GLU GLU D . n 
D 1 12  PRO 12  10  10  PRO PRO D . n 
D 1 13  ASN 13  11  11  ASN ASN D . n 
D 1 14  ALA 14  12  12  ALA ALA D . n 
D 1 15  LEU 15  13  13  LEU LEU D . n 
D 1 16  LEU 16  14  14  LEU LEU D . n 
D 1 17  SER 17  15  15  SER SER D . n 
D 1 18  TYR 18  16  16  TYR TYR D . n 
D 1 19  ASP 19  17  17  ASP ASP D . n 
D 1 20  PHE 20  18  18  PHE PHE D . n 
D 1 21  ASP 21  19  19  ASP ASP D . n 
D 1 22  ARG 22  20  20  ARG ARG D . n 
D 1 23  GLY 23  21  21  GLY GLY D . n 
D 1 24  SER 24  22  22  SER SER D . n 
D 1 25  ASN 25  23  23  ASN ASN D . n 
D 1 26  TYR 26  24  24  TYR TYR D . n 
D 1 27  GLU 27  25  25  GLU GLU D . n 
D 1 28  ASN 28  26  26  ASN ASN D . n 
D 1 29  VAL 29  27  27  VAL VAL D . n 
D 1 30  LEU 30  28  28  LEU LEU D . n 
D 1 31  HIS 31  29  29  HIS HIS D . n 
D 1 32  LEU 32  30  30  LEU LEU D . n 
D 1 33  THR 33  31  31  THR THR D . n 
D 1 34  ASP 34  32  32  ASP ASP D . n 
D 1 35  ALA 35  33  33  ALA ALA D . n 
D 1 36  LEU 36  34  34  LEU LEU D . n 
D 1 37  GLY 37  35  35  GLY GLY D . n 
D 1 38  ALA 38  36  36  ALA ALA D . n 
D 1 39  LEU 39  37  37  LEU LEU D . n 
D 1 40  VAL 40  38  38  VAL VAL D . n 
D 1 41  PRO 41  39  39  PRO PRO D . n 
D 1 42  GLU 42  40  40  GLU GLU D . n 
D 1 43  SER 43  41  41  SER SER D . n 
D 1 44  GLU 44  42  42  GLU GLU D . n 
D 1 45  THR 45  43  43  THR THR D . n 
D 1 46  GLU 46  44  44  GLU GLU D . n 
D 1 47  HIS 47  45  45  HIS HIS D . n 
D 1 48  PRO 48  46  46  PRO PRO D . n 
D 1 49  ASP 49  47  47  ASP ASP D . n 
D 1 50  GLN 50  48  48  GLN GLN D . n 
D 1 51  ARG 51  49  49  ARG ARG D . n 
D 1 52  PHE 52  50  50  PHE PHE D . n 
D 1 53  PHE 53  51  51  PHE PHE D . n 
D 1 54  GLN 54  52  52  GLN GLN D . n 
D 1 55  VAL 55  53  53  VAL VAL D . n 
D 1 56  THR 56  54  54  THR THR D . n 
D 1 57  HIS 57  55  55  HIS HIS D . n 
D 1 58  LEU 58  56  56  LEU LEU D . n 
D 1 59  ILE 59  57  57  ILE ILE D . n 
D 1 60  THR 60  58  58  THR THR D . n 
D 1 61  GLU 61  59  59  GLU GLU D . n 
D 1 62  TYR 62  60  60  TYR TYR D . n 
D 1 63  ALA 63  61  61  ALA ALA D . n 
D 1 64  TRP 64  62  62  TRP TRP D . n 
D 1 65  VAL 65  63  63  VAL VAL D . n 
D 1 66  GLN 66  64  64  GLN GLN D . n 
D 1 67  VAL 67  65  65  VAL VAL D . n 
D 1 68  HIS 68  66  66  HIS HIS D . n 
D 1 69  TYR 69  67  67  TYR TYR D . n 
D 1 70  GLU 70  68  68  GLU GLU D . n 
D 1 71  LEU 71  69  69  LEU LEU D . n 
D 1 72  ARG 72  70  70  ARG ARG D . n 
D 1 73  ARG 73  71  71  ARG ARG D . n 
D 1 74  ALA 74  72  72  ALA ALA D . n 
D 1 75  ILE 75  73  73  ILE ILE D . n 
D 1 76  GLY 76  74  74  GLY GLY D . n 
D 1 77  HIS 77  75  75  HIS HIS D . n 
D 1 78  LEU 78  76  76  LEU LEU D . n 
D 1 79  ASP 79  77  77  ASP ASP D . n 
D 1 80  GLU 80  78  78  GLU GLU D . n 
D 1 81  ASP 81  79  79  ASP ASP D . n 
D 1 82  ARG 82  80  80  ARG ARG D . n 
D 1 83  TYR 83  81  81  TYR TYR D . n 
D 1 84  HIS 84  82  82  HIS HIS D . n 
D 1 85  GLN 85  83  83  GLN GLN D . n 
D 1 86  ALA 86  84  84  ALA ALA D . n 
D 1 87  VAL 87  85  85  VAL VAL D . n 
D 1 88  ARG 88  86  86  ARG ARG D . n 
D 1 89  MET 89  87  87  MET MET D . n 
D 1 90  PHE 90  88  88  PHE PHE D . n 
D 1 91  ASP 91  89  89  ASP ASP D . n 
D 1 92  ARG 92  90  90  ARG ARG D . n 
D 1 93  ALA 93  91  91  ALA ALA D . n 
D 1 94  THR 94  92  92  THR THR D . n 
D 1 95  GLY 95  93  93  GLY GLY D . n 
D 1 96  LEU 96  94  94  LEU LEU D . n 
D 1 97  SER 97  95  95  SER SER D . n 
D 1 98  GLU 98  96  96  GLU GLU D . n 
D 1 99  VAL 99  97  97  VAL VAL D . n 
D 1 100 THR 100 98  98  THR THR D . n 
D 1 101 VAL 101 99  99  VAL VAL D . n 
D 1 102 GLN 102 100 100 GLN GLN D . n 
D 1 103 ALA 103 101 101 ALA ALA D . n 
D 1 104 VAL 104 102 102 VAL VAL D . n 
D 1 105 ARG 105 103 103 ARG ARG D . n 
D 1 106 LEU 106 104 104 LEU LEU D . n 
D 1 107 LEU 107 105 105 LEU LEU D . n 
D 1 108 THR 108 106 106 THR THR D . n 
D 1 109 ASP 109 107 107 ASP ASP D . n 
D 1 110 HIS 110 108 108 HIS HIS D . n 
D 1 111 LEU 111 109 109 LEU LEU D . n 
D 1 112 PRO 112 110 110 PRO PRO D . n 
D 1 113 GLN 113 111 111 GLN GLN D . n 
D 1 114 HIS 114 112 112 HIS HIS D . n 
D 1 115 SER 115 113 113 SER SER D . n 
D 1 116 LEU 116 114 114 LEU LEU D . n 
D 1 117 LEU 117 115 115 LEU LEU D . n 
D 1 118 MET 118 116 116 MET MET D . n 
D 1 119 MET 119 117 117 MET MET D . n 
D 1 120 ARG 120 118 118 ARG ARG D . n 
D 1 121 ASN 121 119 119 ASN ASN D . n 
D 1 122 ALA 122 120 120 ALA ALA D . n 
D 1 123 LEU 123 121 121 LEU LEU D . n 
D 1 124 PRO 124 122 122 PRO PRO D . n 
D 1 125 GLU 125 123 123 GLU GLU D . n 
D 1 126 ASP 126 124 124 ASP ASP D . n 
D 1 127 ALA 127 125 125 ALA ALA D . n 
D 1 128 THR 128 126 126 THR THR D . n 
D 1 129 GLY 129 127 127 GLY GLY D . n 
D 1 130 LEU 130 128 128 LEU LEU D . n 
D 1 131 ASP 131 129 129 ASP ASP D . n 
D 1 132 SER 132 130 130 SER SER D . n 
D 1 133 PRO 133 131 131 PRO PRO D . n 
D 1 134 GLY 134 132 132 GLY GLY D . n 
D 1 135 TYR 135 133 133 TYR TYR D . n 
D 1 136 ARG 136 134 134 ARG ARG D . n 
D 1 137 ASN 137 135 135 ASN ASN D . n 
D 1 138 LEU 138 136 136 LEU LEU D . n 
D 1 139 ARG 139 137 137 ARG ARG D . n 
D 1 140 ARG 140 138 138 ARG ARG D . n 
D 1 141 VAL 141 139 139 VAL VAL D . n 
D 1 142 ALA 142 140 140 ALA ALA D . n 
D 1 143 ARG 143 141 141 ARG ARG D . n 
D 1 144 PRO 144 142 142 PRO PRO D . n 
D 1 145 VAL 145 143 143 VAL VAL D . n 
D 1 146 TRP 146 144 144 TRP TRP D . n 
D 1 147 LYS 147 145 145 LYS LYS D . n 
D 1 148 ALA 148 146 146 ALA ALA D . n 
D 1 149 TYR 149 147 147 TYR TYR D . n 
D 1 150 GLU 150 148 148 GLU GLU D . n 
D 1 151 GLN 151 149 149 GLN GLN D . n 
D 1 152 ALA 152 150 150 ALA ALA D . n 
D 1 153 VAL 153 151 151 VAL VAL D . n 
D 1 154 GLU 154 152 152 GLU GLU D . n 
D 1 155 ARG 155 153 153 ARG ARG D . n 
D 1 156 ALA 156 154 154 ALA ALA D . n 
D 1 157 GLY 157 155 155 GLY GLY D . n 
D 1 158 LEU 158 156 156 LEU LEU D . n 
D 1 159 SER 159 157 157 SER SER D . n 
D 1 160 LEU 160 158 158 LEU LEU D . n 
D 1 161 GLN 161 159 159 GLN GLN D . n 
D 1 162 ASP 162 160 160 ASP ASP D . n 
D 1 163 VAL 163 161 161 VAL VAL D . n 
D 1 164 ILE 164 162 162 ILE ILE D . n 
D 1 165 ALA 165 163 163 ALA ALA D . n 
D 1 166 GLN 166 164 164 GLN GLN D . n 
D 1 167 GLN 167 165 165 GLN GLN D . n 
D 1 168 ASP 168 166 166 ASP ASP D . n 
D 1 169 ASP 169 167 167 ASP ASP D . n 
D 1 170 GLY 170 168 168 GLY GLY D . n 
D 1 171 TYR 171 169 169 TYR TYR D . n 
D 1 172 ASP 172 170 170 ASP ASP D . n 
D 1 173 GLY 173 171 171 GLY GLY D . n 
D 1 174 PRO 174 172 172 PRO PRO D . n 
D 1 175 ARG 175 173 173 ARG ARG D . n 
D 1 176 SER 176 174 174 SER SER D . n 
D 1 177 GLY 177 175 175 GLY GLY D . n 
D 1 178 GLY 178 176 176 GLY GLY D . n 
D 1 179 SER 179 177 177 SER SER D . n 
D 1 180 GLN 180 178 178 GLN GLN D . n 
D 1 181 SER 181 179 179 SER SER D . n 
D 1 182 LEU 182 180 180 LEU LEU D . n 
D 1 183 ALA 183 181 181 ALA ALA D . n 
D 1 184 LEU 184 182 182 LEU LEU D . n 
D 1 185 VAL 185 183 183 VAL VAL D . n 
D 1 186 ARG 186 184 184 ARG ARG D . n 
D 1 187 GLU 187 185 185 GLU GLU D . n 
D 1 188 ALA 188 186 186 ALA ALA D . n 
D 1 189 MET 189 187 187 MET MET D . n 
D 1 190 LEU 190 188 188 LEU LEU D . n 
D 1 191 ARG 191 189 189 ARG ARG D . n 
D 1 192 LEU 192 190 190 LEU LEU D . n 
D 1 193 ASP 193 191 191 ASP ASP D . n 
D 1 194 GLY 194 192 192 GLY GLY D . n 
D 1 195 SER 195 193 193 SER SER D . n 
D 1 196 VAL 196 194 194 VAL VAL D . n 
D 1 197 LEU 197 195 195 LEU LEU D . n 
D 1 198 GLY 198 196 196 GLY GLY D . n 
D 1 199 TRP 199 197 197 TRP TRP D . n 
D 1 200 LYS 200 198 198 LYS LYS D . n 
D 1 201 GLN 201 199 199 GLN GLN D . n 
D 1 202 HIS 202 200 200 HIS HIS D . n 
D 1 203 HIS 203 201 201 HIS HIS D . n 
D 1 204 LEU 204 202 202 LEU LEU D . n 
D 1 205 ILE 205 203 203 ILE ILE D . n 
D 1 206 MET 206 204 204 MET MET D . n 
D 1 207 VAL 207 205 205 VAL VAL D . n 
D 1 208 TRP 208 206 206 TRP TRP D . n 
D 1 209 SER 209 207 207 SER SER D . n 
D 1 210 GLN 210 208 208 GLN GLN D . n 
D 1 211 LEU 211 209 209 LEU LEU D . n 
D 1 212 GLY 212 210 210 GLY GLY D . n 
D 1 213 GLY 213 211 211 GLY GLY D . n 
D 1 214 GLN 214 212 212 GLN GLN D . n 
D 1 215 PRO 215 213 213 PRO PRO D . n 
D 1 216 GLY 216 214 214 GLY GLY D . n 
D 1 217 LEU 217 215 215 LEU LEU D . n 
D 1 218 ARG 218 216 ?   ?   ?   D . n 
D 1 219 LYS 219 217 ?   ?   ?   D . n 
D 1 220 GLY 220 218 ?   ?   ?   D . n 
D 1 221 ASN 221 219 ?   ?   ?   D . n 
D 1 222 GLU 222 220 ?   ?   ?   D . n 
D 1 223 GLU 223 221 ?   ?   ?   D . n 
D 1 224 GLY 224 222 ?   ?   ?   D . n 
D 1 225 ASP 225 223 ?   ?   ?   D . n 
D 1 226 ASP 226 224 ?   ?   ?   D . n 
D 1 227 GLY 227 225 ?   ?   ?   D . n 
D 1 228 LEU 228 226 ?   ?   ?   D . n 
D 1 229 GLU 229 227 227 GLU GLU D . n 
D 1 230 LEU 230 228 228 LEU LEU D . n 
D 1 231 PRO 231 229 229 PRO PRO D . n 
D 1 232 GLN 232 230 230 GLN GLN D . n 
D 1 233 SER 233 231 231 SER SER D . n 
D 1 234 LEU 234 232 232 LEU LEU D . n 
D 1 235 GLY 235 233 233 GLY GLY D . n 
D 1 236 GLY 236 234 234 GLY GLY D . n 
D 1 237 ARG 237 235 235 ARG ARG D . n 
D 1 238 SER 238 236 236 SER SER D . n 
D 1 239 LEU 239 237 237 LEU LEU D . n 
D 1 240 ALA 240 238 238 ALA ALA D . n 
D 1 241 THR 241 239 239 THR THR D . n 
D 1 242 LEU 242 240 240 LEU LEU D . n 
D 1 243 GLU 243 241 241 GLU GLU D . n 
D 1 244 ALA 244 242 242 ALA ALA D . n 
D 1 245 ARG 245 243 243 ARG ARG D . n 
D 1 246 SER 246 244 244 SER SER D . n 
D 1 247 GLN 247 245 245 GLN GLN D . n 
D 1 248 LEU 248 246 246 LEU LEU D . n 
D 1 249 ALA 249 247 247 ALA ALA D . n 
D 1 250 LEU 250 248 248 LEU LEU D . n 
D 1 251 PHE 251 249 249 PHE PHE D . n 
D 1 252 PRO 252 250 250 PRO PRO D . n 
D 1 253 GLU 253 251 251 GLU GLU D . n 
D 1 254 LEU 254 252 252 LEU LEU D . n 
D 1 255 TRP 255 253 253 TRP TRP D . n 
D 1 256 ARG 256 254 254 ARG ARG D . n 
D 1 257 ALA 257 255 255 ALA ALA D . n 
D 1 258 ALA 258 256 256 ALA ALA D . n 
D 1 259 GLU 259 257 257 GLU GLU D . n 
D 1 260 ASP 260 258 258 ASP ASP D . n 
D 1 261 ALA 261 259 259 ALA ALA D . n 
D 1 262 TYR 262 260 260 TYR TYR D . n 
D 1 263 TRP 263 261 261 TRP TRP D . n 
D 1 264 LEU 264 262 262 LEU LEU D . n 
D 1 265 LEU 265 263 263 LEU LEU D . n 
D 1 266 GLY 266 264 264 GLY GLY D . n 
D 1 267 THR 267 265 265 THR THR D . n 
D 1 268 ARG 268 266 266 ARG ARG D . n 
D 1 269 HIS 269 267 267 HIS HIS D . n 
D 1 270 ASP 270 268 268 ASP ASP D . n 
D 1 271 THR 271 269 269 THR THR D . n 
D 1 272 ASP 272 270 ?   ?   ?   D . n 
D 1 273 ALA 273 271 ?   ?   ?   D . n 
D 1 274 PRO 274 272 ?   ?   ?   D . n 
D 1 275 VAL 275 273 ?   ?   ?   D . n 
D 1 276 ARG 276 274 ?   ?   ?   D . n 
D 1 277 GLY 277 275 ?   ?   ?   D . n 
D 1 278 GLY 278 276 ?   ?   ?   D . n 
D 1 279 GLY 279 277 ?   ?   ?   D . n 
D 1 280 ASN 280 278 ?   ?   ?   D . n 
D 1 281 GLY 281 279 ?   ?   ?   D . n 
D 1 282 SER 282 280 ?   ?   ?   D . n 
D 1 283 PRO 283 281 ?   ?   ?   D . n 
D 1 284 VAL 284 282 ?   ?   ?   D . n 
D 1 285 GLN 285 283 ?   ?   ?   D . n 
D 1 286 HIS 286 284 ?   ?   ?   D . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 78U ? ? 78U ? ? 'SUBJECT OF INVESTIGATION' ? 
2 CYN ? ? CYN ? ? 'SUBJECT OF INVESTIGATION' ? 
3 HEM ? ? HEM ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 HEM 1   301 301 HEM HEM A . 
F 3 CYN 1   302 401 CYN CYN A . 
G 4 78U 1   303 501 78U 78U A . 
H 2 HEM 1   301 301 HEM HEM B . 
I 3 CYN 1   302 401 CYN CYN B . 
J 4 78U 1   303 501 78U 78U B . 
K 2 HEM 1   301 301 HEM HEM C . 
L 3 CYN 1   302 401 CYN CYN C . 
M 4 78U 1   303 501 78U 78U C . 
N 2 HEM 1   301 301 HEM HEM D . 
O 3 CYN 1   302 401 CYN CYN D . 
P 4 78U 1   303 501 78U 78U D . 
Q 5 HOH 1   401 314 HOH HOH A . 
Q 5 HOH 2   402 193 HOH HOH A . 
Q 5 HOH 3   403 279 HOH HOH A . 
Q 5 HOH 4   404 344 HOH HOH A . 
Q 5 HOH 5   405 148 HOH HOH A . 
Q 5 HOH 6   406 535 HOH HOH A . 
Q 5 HOH 7   407 353 HOH HOH A . 
Q 5 HOH 8   408 152 HOH HOH A . 
Q 5 HOH 9   409 245 HOH HOH A . 
Q 5 HOH 10  410 175 HOH HOH A . 
Q 5 HOH 11  411 252 HOH HOH A . 
Q 5 HOH 12  412 299 HOH HOH A . 
Q 5 HOH 13  413 243 HOH HOH A . 
Q 5 HOH 14  414 61  HOH HOH A . 
Q 5 HOH 15  415 384 HOH HOH A . 
Q 5 HOH 16  416 195 HOH HOH A . 
Q 5 HOH 17  417 219 HOH HOH A . 
Q 5 HOH 18  418 161 HOH HOH A . 
Q 5 HOH 19  419 172 HOH HOH A . 
Q 5 HOH 20  420 194 HOH HOH A . 
Q 5 HOH 21  421 192 HOH HOH A . 
Q 5 HOH 22  422 491 HOH HOH A . 
Q 5 HOH 23  423 203 HOH HOH A . 
Q 5 HOH 24  424 340 HOH HOH A . 
Q 5 HOH 25  425 171 HOH HOH A . 
Q 5 HOH 26  426 28  HOH HOH A . 
Q 5 HOH 27  427 402 HOH HOH A . 
Q 5 HOH 28  428 236 HOH HOH A . 
Q 5 HOH 29  429 12  HOH HOH A . 
Q 5 HOH 30  430 43  HOH HOH A . 
Q 5 HOH 31  431 503 HOH HOH A . 
Q 5 HOH 32  432 77  HOH HOH A . 
Q 5 HOH 33  433 14  HOH HOH A . 
Q 5 HOH 34  434 4   HOH HOH A . 
Q 5 HOH 35  435 514 HOH HOH A . 
Q 5 HOH 36  436 156 HOH HOH A . 
Q 5 HOH 37  437 347 HOH HOH A . 
Q 5 HOH 38  438 226 HOH HOH A . 
Q 5 HOH 39  439 106 HOH HOH A . 
Q 5 HOH 40  440 176 HOH HOH A . 
Q 5 HOH 41  441 59  HOH HOH A . 
Q 5 HOH 42  442 6   HOH HOH A . 
Q 5 HOH 43  443 128 HOH HOH A . 
Q 5 HOH 44  444 383 HOH HOH A . 
Q 5 HOH 45  445 199 HOH HOH A . 
Q 5 HOH 46  446 92  HOH HOH A . 
Q 5 HOH 47  447 235 HOH HOH A . 
Q 5 HOH 48  448 85  HOH HOH A . 
Q 5 HOH 49  449 164 HOH HOH A . 
Q 5 HOH 50  450 276 HOH HOH A . 
Q 5 HOH 51  451 444 HOH HOH A . 
Q 5 HOH 52  452 68  HOH HOH A . 
Q 5 HOH 53  453 150 HOH HOH A . 
Q 5 HOH 54  454 135 HOH HOH A . 
Q 5 HOH 55  455 112 HOH HOH A . 
Q 5 HOH 56  456 33  HOH HOH A . 
Q 5 HOH 57  457 286 HOH HOH A . 
Q 5 HOH 58  458 486 HOH HOH A . 
Q 5 HOH 59  459 16  HOH HOH A . 
Q 5 HOH 60  460 163 HOH HOH A . 
Q 5 HOH 61  461 238 HOH HOH A . 
Q 5 HOH 62  462 259 HOH HOH A . 
Q 5 HOH 63  463 25  HOH HOH A . 
Q 5 HOH 64  464 341 HOH HOH A . 
Q 5 HOH 65  465 445 HOH HOH A . 
Q 5 HOH 66  466 208 HOH HOH A . 
Q 5 HOH 67  467 304 HOH HOH A . 
Q 5 HOH 68  468 300 HOH HOH A . 
Q 5 HOH 69  469 386 HOH HOH A . 
Q 5 HOH 70  470 277 HOH HOH A . 
Q 5 HOH 71  471 223 HOH HOH A . 
Q 5 HOH 72  472 241 HOH HOH A . 
Q 5 HOH 73  473 357 HOH HOH A . 
Q 5 HOH 74  474 72  HOH HOH A . 
Q 5 HOH 75  475 472 HOH HOH A . 
Q 5 HOH 76  476 427 HOH HOH A . 
Q 5 HOH 77  477 89  HOH HOH A . 
Q 5 HOH 78  478 532 HOH HOH A . 
Q 5 HOH 79  479 424 HOH HOH A . 
Q 5 HOH 80  480 407 HOH HOH A . 
Q 5 HOH 81  481 363 HOH HOH A . 
Q 5 HOH 82  482 275 HOH HOH A . 
Q 5 HOH 83  483 69  HOH HOH A . 
Q 5 HOH 84  484 489 HOH HOH A . 
Q 5 HOH 85  485 305 HOH HOH A . 
Q 5 HOH 86  486 493 HOH HOH A . 
Q 5 HOH 87  487 274 HOH HOH A . 
Q 5 HOH 88  488 330 HOH HOH A . 
Q 5 HOH 89  489 426 HOH HOH A . 
Q 5 HOH 90  490 523 HOH HOH A . 
Q 5 HOH 91  491 345 HOH HOH A . 
Q 5 HOH 92  492 373 HOH HOH A . 
Q 5 HOH 93  493 511 HOH HOH A . 
Q 5 HOH 94  494 466 HOH HOH A . 
Q 5 HOH 95  495 490 HOH HOH A . 
Q 5 HOH 96  496 497 HOH HOH A . 
Q 5 HOH 97  497 417 HOH HOH A . 
Q 5 HOH 98  498 469 HOH HOH A . 
Q 5 HOH 99  499 481 HOH HOH A . 
Q 5 HOH 100 500 316 HOH HOH A . 
R 5 HOH 1   401 474 HOH HOH B . 
R 5 HOH 2   402 322 HOH HOH B . 
R 5 HOH 3   403 433 HOH HOH B . 
R 5 HOH 4   404 462 HOH HOH B . 
R 5 HOH 5   405 79  HOH HOH B . 
R 5 HOH 6   406 436 HOH HOH B . 
R 5 HOH 7   407 7   HOH HOH B . 
R 5 HOH 8   408 346 HOH HOH B . 
R 5 HOH 9   409 189 HOH HOH B . 
R 5 HOH 10  410 371 HOH HOH B . 
R 5 HOH 11  411 287 HOH HOH B . 
R 5 HOH 12  412 256 HOH HOH B . 
R 5 HOH 13  413 394 HOH HOH B . 
R 5 HOH 14  414 358 HOH HOH B . 
R 5 HOH 15  415 162 HOH HOH B . 
R 5 HOH 16  416 52  HOH HOH B . 
R 5 HOH 17  417 78  HOH HOH B . 
R 5 HOH 18  418 214 HOH HOH B . 
R 5 HOH 19  419 231 HOH HOH B . 
R 5 HOH 20  420 307 HOH HOH B . 
R 5 HOH 21  421 159 HOH HOH B . 
R 5 HOH 22  422 467 HOH HOH B . 
R 5 HOH 23  423 328 HOH HOH B . 
R 5 HOH 24  424 111 HOH HOH B . 
R 5 HOH 25  425 154 HOH HOH B . 
R 5 HOH 26  426 127 HOH HOH B . 
R 5 HOH 27  427 399 HOH HOH B . 
R 5 HOH 28  428 333 HOH HOH B . 
R 5 HOH 29  429 301 HOH HOH B . 
R 5 HOH 30  430 260 HOH HOH B . 
R 5 HOH 31  431 66  HOH HOH B . 
R 5 HOH 32  432 293 HOH HOH B . 
R 5 HOH 33  433 437 HOH HOH B . 
R 5 HOH 34  434 400 HOH HOH B . 
R 5 HOH 35  435 3   HOH HOH B . 
R 5 HOH 36  436 264 HOH HOH B . 
R 5 HOH 37  437 50  HOH HOH B . 
R 5 HOH 38  438 222 HOH HOH B . 
R 5 HOH 39  439 257 HOH HOH B . 
R 5 HOH 40  440 15  HOH HOH B . 
R 5 HOH 41  441 460 HOH HOH B . 
R 5 HOH 42  442 382 HOH HOH B . 
R 5 HOH 43  443 41  HOH HOH B . 
R 5 HOH 44  444 9   HOH HOH B . 
R 5 HOH 45  445 531 HOH HOH B . 
R 5 HOH 46  446 530 HOH HOH B . 
R 5 HOH 47  447 51  HOH HOH B . 
R 5 HOH 48  448 83  HOH HOH B . 
R 5 HOH 49  449 165 HOH HOH B . 
R 5 HOH 50  450 118 HOH HOH B . 
R 5 HOH 51  451 100 HOH HOH B . 
R 5 HOH 52  452 291 HOH HOH B . 
R 5 HOH 53  453 327 HOH HOH B . 
R 5 HOH 54  454 84  HOH HOH B . 
R 5 HOH 55  455 439 HOH HOH B . 
R 5 HOH 56  456 45  HOH HOH B . 
R 5 HOH 57  457 179 HOH HOH B . 
R 5 HOH 58  458 11  HOH HOH B . 
R 5 HOH 59  459 8   HOH HOH B . 
R 5 HOH 60  460 20  HOH HOH B . 
R 5 HOH 61  461 34  HOH HOH B . 
R 5 HOH 62  462 145 HOH HOH B . 
R 5 HOH 63  463 81  HOH HOH B . 
R 5 HOH 64  464 158 HOH HOH B . 
R 5 HOH 65  465 365 HOH HOH B . 
R 5 HOH 66  466 32  HOH HOH B . 
R 5 HOH 67  467 122 HOH HOH B . 
R 5 HOH 68  468 385 HOH HOH B . 
R 5 HOH 69  469 335 HOH HOH B . 
R 5 HOH 70  470 498 HOH HOH B . 
R 5 HOH 71  471 479 HOH HOH B . 
R 5 HOH 72  472 348 HOH HOH B . 
R 5 HOH 73  473 58  HOH HOH B . 
R 5 HOH 74  474 126 HOH HOH B . 
R 5 HOH 75  475 239 HOH HOH B . 
R 5 HOH 76  476 177 HOH HOH B . 
R 5 HOH 77  477 44  HOH HOH B . 
R 5 HOH 78  478 116 HOH HOH B . 
R 5 HOH 79  479 36  HOH HOH B . 
R 5 HOH 80  480 151 HOH HOH B . 
R 5 HOH 81  481 297 HOH HOH B . 
R 5 HOH 82  482 461 HOH HOH B . 
R 5 HOH 83  483 332 HOH HOH B . 
R 5 HOH 84  484 431 HOH HOH B . 
R 5 HOH 85  485 338 HOH HOH B . 
R 5 HOH 86  486 110 HOH HOH B . 
R 5 HOH 87  487 411 HOH HOH B . 
R 5 HOH 88  488 108 HOH HOH B . 
R 5 HOH 89  489 331 HOH HOH B . 
R 5 HOH 90  490 249 HOH HOH B . 
R 5 HOH 91  491 370 HOH HOH B . 
R 5 HOH 92  492 173 HOH HOH B . 
R 5 HOH 93  493 170 HOH HOH B . 
R 5 HOH 94  494 178 HOH HOH B . 
R 5 HOH 95  495 88  HOH HOH B . 
R 5 HOH 96  496 388 HOH HOH B . 
R 5 HOH 97  497 393 HOH HOH B . 
R 5 HOH 98  498 186 HOH HOH B . 
R 5 HOH 99  499 57  HOH HOH B . 
R 5 HOH 100 500 233 HOH HOH B . 
R 5 HOH 101 501 73  HOH HOH B . 
R 5 HOH 102 502 184 HOH HOH B . 
R 5 HOH 103 503 21  HOH HOH B . 
R 5 HOH 104 504 263 HOH HOH B . 
R 5 HOH 105 505 309 HOH HOH B . 
R 5 HOH 106 506 296 HOH HOH B . 
R 5 HOH 107 507 262 HOH HOH B . 
R 5 HOH 108 508 389 HOH HOH B . 
R 5 HOH 109 509 99  HOH HOH B . 
R 5 HOH 110 510 265 HOH HOH B . 
R 5 HOH 111 511 283 HOH HOH B . 
R 5 HOH 112 512 234 HOH HOH B . 
R 5 HOH 113 513 253 HOH HOH B . 
R 5 HOH 114 514 454 HOH HOH B . 
R 5 HOH 115 515 272 HOH HOH B . 
R 5 HOH 116 516 280 HOH HOH B . 
R 5 HOH 117 517 155 HOH HOH B . 
R 5 HOH 118 518 273 HOH HOH B . 
R 5 HOH 119 519 378 HOH HOH B . 
R 5 HOH 120 520 113 HOH HOH B . 
R 5 HOH 121 521 409 HOH HOH B . 
R 5 HOH 122 522 533 HOH HOH B . 
R 5 HOH 123 523 138 HOH HOH B . 
R 5 HOH 124 524 492 HOH HOH B . 
R 5 HOH 125 525 478 HOH HOH B . 
R 5 HOH 126 526 456 HOH HOH B . 
R 5 HOH 127 527 419 HOH HOH B . 
R 5 HOH 128 528 196 HOH HOH B . 
R 5 HOH 129 529 355 HOH HOH B . 
R 5 HOH 130 530 463 HOH HOH B . 
R 5 HOH 131 531 220 HOH HOH B . 
R 5 HOH 132 532 86  HOH HOH B . 
R 5 HOH 133 533 519 HOH HOH B . 
R 5 HOH 134 534 438 HOH HOH B . 
R 5 HOH 135 535 403 HOH HOH B . 
R 5 HOH 136 536 325 HOH HOH B . 
R 5 HOH 137 537 496 HOH HOH B . 
R 5 HOH 138 538 510 HOH HOH B . 
R 5 HOH 139 539 391 HOH HOH B . 
R 5 HOH 140 540 360 HOH HOH B . 
R 5 HOH 141 541 536 HOH HOH B . 
R 5 HOH 142 542 337 HOH HOH B . 
R 5 HOH 143 543 465 HOH HOH B . 
S 5 HOH 1   401 528 HOH HOH C . 
S 5 HOH 2   402 430 HOH HOH C . 
S 5 HOH 3   403 267 HOH HOH C . 
S 5 HOH 4   404 392 HOH HOH C . 
S 5 HOH 5   405 318 HOH HOH C . 
S 5 HOH 6   406 458 HOH HOH C . 
S 5 HOH 7   407 64  HOH HOH C . 
S 5 HOH 8   408 248 HOH HOH C . 
S 5 HOH 9   409 440 HOH HOH C . 
S 5 HOH 10  410 101 HOH HOH C . 
S 5 HOH 11  411 308 HOH HOH C . 
S 5 HOH 12  412 130 HOH HOH C . 
S 5 HOH 13  413 288 HOH HOH C . 
S 5 HOH 14  414 115 HOH HOH C . 
S 5 HOH 15  415 10  HOH HOH C . 
S 5 HOH 16  416 508 HOH HOH C . 
S 5 HOH 17  417 369 HOH HOH C . 
S 5 HOH 18  418 48  HOH HOH C . 
S 5 HOH 19  419 423 HOH HOH C . 
S 5 HOH 20  420 261 HOH HOH C . 
S 5 HOH 21  421 149 HOH HOH C . 
S 5 HOH 22  422 124 HOH HOH C . 
S 5 HOH 23  423 501 HOH HOH C . 
S 5 HOH 24  424 1   HOH HOH C . 
S 5 HOH 25  425 282 HOH HOH C . 
S 5 HOH 26  426 157 HOH HOH C . 
S 5 HOH 27  427 294 HOH HOH C . 
S 5 HOH 28  428 102 HOH HOH C . 
S 5 HOH 29  429 312 HOH HOH C . 
S 5 HOH 30  430 206 HOH HOH C . 
S 5 HOH 31  431 224 HOH HOH C . 
S 5 HOH 32  432 232 HOH HOH C . 
S 5 HOH 33  433 107 HOH HOH C . 
S 5 HOH 34  434 30  HOH HOH C . 
S 5 HOH 35  435 446 HOH HOH C . 
S 5 HOH 36  436 125 HOH HOH C . 
S 5 HOH 37  437 166 HOH HOH C . 
S 5 HOH 38  438 258 HOH HOH C . 
S 5 HOH 39  439 361 HOH HOH C . 
S 5 HOH 40  440 329 HOH HOH C . 
S 5 HOH 41  441 405 HOH HOH C . 
S 5 HOH 42  442 87  HOH HOH C . 
S 5 HOH 43  443 13  HOH HOH C . 
S 5 HOH 44  444 18  HOH HOH C . 
S 5 HOH 45  445 201 HOH HOH C . 
S 5 HOH 46  446 98  HOH HOH C . 
S 5 HOH 47  447 255 HOH HOH C . 
S 5 HOH 48  448 167 HOH HOH C . 
S 5 HOH 49  449 216 HOH HOH C . 
S 5 HOH 50  450 2   HOH HOH C . 
S 5 HOH 51  451 109 HOH HOH C . 
S 5 HOH 52  452 218 HOH HOH C . 
S 5 HOH 53  453 447 HOH HOH C . 
S 5 HOH 54  454 90  HOH HOH C . 
S 5 HOH 55  455 26  HOH HOH C . 
S 5 HOH 56  456 74  HOH HOH C . 
S 5 HOH 57  457 65  HOH HOH C . 
S 5 HOH 58  458 317 HOH HOH C . 
S 5 HOH 59  459 23  HOH HOH C . 
S 5 HOH 60  460 70  HOH HOH C . 
S 5 HOH 61  461 480 HOH HOH C . 
S 5 HOH 62  462 75  HOH HOH C . 
S 5 HOH 63  463 117 HOH HOH C . 
S 5 HOH 64  464 37  HOH HOH C . 
S 5 HOH 65  465 428 HOH HOH C . 
S 5 HOH 66  466 114 HOH HOH C . 
S 5 HOH 67  467 443 HOH HOH C . 
S 5 HOH 68  468 137 HOH HOH C . 
S 5 HOH 69  469 302 HOH HOH C . 
S 5 HOH 70  470 134 HOH HOH C . 
S 5 HOH 71  471 35  HOH HOH C . 
S 5 HOH 72  472 22  HOH HOH C . 
S 5 HOH 73  473 139 HOH HOH C . 
S 5 HOH 74  474 119 HOH HOH C . 
S 5 HOH 75  475 5   HOH HOH C . 
S 5 HOH 76  476 143 HOH HOH C . 
S 5 HOH 77  477 55  HOH HOH C . 
S 5 HOH 78  478 56  HOH HOH C . 
S 5 HOH 79  479 367 HOH HOH C . 
S 5 HOH 80  480 324 HOH HOH C . 
S 5 HOH 81  481 207 HOH HOH C . 
S 5 HOH 82  482 63  HOH HOH C . 
S 5 HOH 83  483 103 HOH HOH C . 
S 5 HOH 84  484 320 HOH HOH C . 
S 5 HOH 85  485 362 HOH HOH C . 
S 5 HOH 86  486 29  HOH HOH C . 
S 5 HOH 87  487 38  HOH HOH C . 
S 5 HOH 88  488 142 HOH HOH C . 
S 5 HOH 89  489 412 HOH HOH C . 
S 5 HOH 90  490 270 HOH HOH C . 
S 5 HOH 91  491 432 HOH HOH C . 
S 5 HOH 92  492 269 HOH HOH C . 
S 5 HOH 93  493 221 HOH HOH C . 
S 5 HOH 94  494 281 HOH HOH C . 
S 5 HOH 95  495 387 HOH HOH C . 
S 5 HOH 96  496 27  HOH HOH C . 
S 5 HOH 97  497 390 HOH HOH C . 
S 5 HOH 98  498 470 HOH HOH C . 
S 5 HOH 99  499 420 HOH HOH C . 
S 5 HOH 100 500 210 HOH HOH C . 
S 5 HOH 101 501 140 HOH HOH C . 
S 5 HOH 102 502 366 HOH HOH C . 
S 5 HOH 103 503 372 HOH HOH C . 
S 5 HOH 104 504 91  HOH HOH C . 
S 5 HOH 105 505 237 HOH HOH C . 
S 5 HOH 106 506 213 HOH HOH C . 
S 5 HOH 107 507 169 HOH HOH C . 
S 5 HOH 108 508 290 HOH HOH C . 
S 5 HOH 109 509 319 HOH HOH C . 
S 5 HOH 110 510 120 HOH HOH C . 
S 5 HOH 111 511 408 HOH HOH C . 
S 5 HOH 112 512 368 HOH HOH C . 
S 5 HOH 113 513 227 HOH HOH C . 
S 5 HOH 114 514 404 HOH HOH C . 
S 5 HOH 115 515 247 HOH HOH C . 
S 5 HOH 116 516 19  HOH HOH C . 
S 5 HOH 117 517 200 HOH HOH C . 
S 5 HOH 118 518 505 HOH HOH C . 
S 5 HOH 119 519 205 HOH HOH C . 
S 5 HOH 120 520 351 HOH HOH C . 
S 5 HOH 121 521 211 HOH HOH C . 
S 5 HOH 122 522 242 HOH HOH C . 
S 5 HOH 123 523 284 HOH HOH C . 
S 5 HOH 124 524 271 HOH HOH C . 
S 5 HOH 125 525 31  HOH HOH C . 
S 5 HOH 126 526 71  HOH HOH C . 
S 5 HOH 127 527 97  HOH HOH C . 
S 5 HOH 128 528 457 HOH HOH C . 
S 5 HOH 129 529 311 HOH HOH C . 
S 5 HOH 130 530 180 HOH HOH C . 
S 5 HOH 131 531 254 HOH HOH C . 
S 5 HOH 132 532 202 HOH HOH C . 
S 5 HOH 133 533 183 HOH HOH C . 
S 5 HOH 134 534 495 HOH HOH C . 
S 5 HOH 135 535 441 HOH HOH C . 
S 5 HOH 136 536 434 HOH HOH C . 
S 5 HOH 137 537 67  HOH HOH C . 
S 5 HOH 138 538 435 HOH HOH C . 
S 5 HOH 139 539 448 HOH HOH C . 
S 5 HOH 140 540 278 HOH HOH C . 
S 5 HOH 141 541 504 HOH HOH C . 
S 5 HOH 142 542 240 HOH HOH C . 
S 5 HOH 143 543 422 HOH HOH C . 
S 5 HOH 144 544 376 HOH HOH C . 
S 5 HOH 145 545 306 HOH HOH C . 
S 5 HOH 146 546 406 HOH HOH C . 
S 5 HOH 147 547 483 HOH HOH C . 
S 5 HOH 148 548 336 HOH HOH C . 
S 5 HOH 149 549 182 HOH HOH C . 
S 5 HOH 150 550 374 HOH HOH C . 
S 5 HOH 151 551 477 HOH HOH C . 
S 5 HOH 152 552 502 HOH HOH C . 
S 5 HOH 153 553 356 HOH HOH C . 
S 5 HOH 154 554 522 HOH HOH C . 
S 5 HOH 155 555 476 HOH HOH C . 
S 5 HOH 156 556 334 HOH HOH C . 
S 5 HOH 157 557 484 HOH HOH C . 
S 5 HOH 158 558 289 HOH HOH C . 
S 5 HOH 159 559 494 HOH HOH C . 
S 5 HOH 160 560 268 HOH HOH C . 
S 5 HOH 161 561 54  HOH HOH C . 
S 5 HOH 162 562 520 HOH HOH C . 
S 5 HOH 163 563 364 HOH HOH C . 
S 5 HOH 164 564 517 HOH HOH C . 
S 5 HOH 165 565 326 HOH HOH C . 
S 5 HOH 166 566 537 HOH HOH C . 
T 5 HOH 1   401 513 HOH HOH D . 
T 5 HOH 2   402 76  HOH HOH D . 
T 5 HOH 3   403 212 HOH HOH D . 
T 5 HOH 4   404 131 HOH HOH D . 
T 5 HOH 5   405 244 HOH HOH D . 
T 5 HOH 6   406 229 HOH HOH D . 
T 5 HOH 7   407 350 HOH HOH D . 
T 5 HOH 8   408 146 HOH HOH D . 
T 5 HOH 9   409 375 HOH HOH D . 
T 5 HOH 10  410 524 HOH HOH D . 
T 5 HOH 11  411 181 HOH HOH D . 
T 5 HOH 12  412 512 HOH HOH D . 
T 5 HOH 13  413 377 HOH HOH D . 
T 5 HOH 14  414 421 HOH HOH D . 
T 5 HOH 15  415 415 HOH HOH D . 
T 5 HOH 16  416 285 HOH HOH D . 
T 5 HOH 17  417 298 HOH HOH D . 
T 5 HOH 18  418 500 HOH HOH D . 
T 5 HOH 19  419 80  HOH HOH D . 
T 5 HOH 20  420 121 HOH HOH D . 
T 5 HOH 21  421 230 HOH HOH D . 
T 5 HOH 22  422 459 HOH HOH D . 
T 5 HOH 23  423 217 HOH HOH D . 
T 5 HOH 24  424 468 HOH HOH D . 
T 5 HOH 25  425 190 HOH HOH D . 
T 5 HOH 26  426 209 HOH HOH D . 
T 5 HOH 27  427 246 HOH HOH D . 
T 5 HOH 28  428 315 HOH HOH D . 
T 5 HOH 29  429 17  HOH HOH D . 
T 5 HOH 30  430 185 HOH HOH D . 
T 5 HOH 31  431 129 HOH HOH D . 
T 5 HOH 32  432 197 HOH HOH D . 
T 5 HOH 33  433 343 HOH HOH D . 
T 5 HOH 34  434 455 HOH HOH D . 
T 5 HOH 35  435 136 HOH HOH D . 
T 5 HOH 36  436 93  HOH HOH D . 
T 5 HOH 37  437 401 HOH HOH D . 
T 5 HOH 38  438 506 HOH HOH D . 
T 5 HOH 39  439 342 HOH HOH D . 
T 5 HOH 40  440 40  HOH HOH D . 
T 5 HOH 41  441 123 HOH HOH D . 
T 5 HOH 42  442 94  HOH HOH D . 
T 5 HOH 43  443 225 HOH HOH D . 
T 5 HOH 44  444 292 HOH HOH D . 
T 5 HOH 45  445 396 HOH HOH D . 
T 5 HOH 46  446 251 HOH HOH D . 
T 5 HOH 47  447 321 HOH HOH D . 
T 5 HOH 48  448 303 HOH HOH D . 
T 5 HOH 49  449 516 HOH HOH D . 
T 5 HOH 50  450 62  HOH HOH D . 
T 5 HOH 51  451 42  HOH HOH D . 
T 5 HOH 52  452 39  HOH HOH D . 
T 5 HOH 53  453 174 HOH HOH D . 
T 5 HOH 54  454 132 HOH HOH D . 
T 5 HOH 55  455 47  HOH HOH D . 
T 5 HOH 56  456 198 HOH HOH D . 
T 5 HOH 57  457 160 HOH HOH D . 
T 5 HOH 58  458 53  HOH HOH D . 
T 5 HOH 59  459 529 HOH HOH D . 
T 5 HOH 60  460 104 HOH HOH D . 
T 5 HOH 61  461 250 HOH HOH D . 
T 5 HOH 62  462 485 HOH HOH D . 
T 5 HOH 63  463 266 HOH HOH D . 
T 5 HOH 64  464 359 HOH HOH D . 
T 5 HOH 65  465 96  HOH HOH D . 
T 5 HOH 66  466 453 HOH HOH D . 
T 5 HOH 67  467 60  HOH HOH D . 
T 5 HOH 68  468 46  HOH HOH D . 
T 5 HOH 69  469 450 HOH HOH D . 
T 5 HOH 70  470 82  HOH HOH D . 
T 5 HOH 71  471 323 HOH HOH D . 
T 5 HOH 72  472 380 HOH HOH D . 
T 5 HOH 73  473 413 HOH HOH D . 
T 5 HOH 74  474 379 HOH HOH D . 
T 5 HOH 75  475 395 HOH HOH D . 
T 5 HOH 76  476 310 HOH HOH D . 
T 5 HOH 77  477 410 HOH HOH D . 
T 5 HOH 78  478 95  HOH HOH D . 
T 5 HOH 79  479 24  HOH HOH D . 
T 5 HOH 80  480 352 HOH HOH D . 
T 5 HOH 81  481 499 HOH HOH D . 
T 5 HOH 82  482 49  HOH HOH D . 
T 5 HOH 83  483 397 HOH HOH D . 
T 5 HOH 84  484 354 HOH HOH D . 
T 5 HOH 85  485 228 HOH HOH D . 
T 5 HOH 86  486 295 HOH HOH D . 
T 5 HOH 87  487 133 HOH HOH D . 
T 5 HOH 88  488 141 HOH HOH D . 
T 5 HOH 89  489 416 HOH HOH D . 
T 5 HOH 90  490 313 HOH HOH D . 
T 5 HOH 91  491 187 HOH HOH D . 
T 5 HOH 92  492 525 HOH HOH D . 
T 5 HOH 93  493 188 HOH HOH D . 
T 5 HOH 94  494 147 HOH HOH D . 
T 5 HOH 95  495 418 HOH HOH D . 
T 5 HOH 96  496 168 HOH HOH D . 
T 5 HOH 97  497 191 HOH HOH D . 
T 5 HOH 98  498 398 HOH HOH D . 
T 5 HOH 99  499 534 HOH HOH D . 
T 5 HOH 100 500 349 HOH HOH D . 
T 5 HOH 101 501 429 HOH HOH D . 
T 5 HOH 102 502 442 HOH HOH D . 
T 5 HOH 103 503 144 HOH HOH D . 
T 5 HOH 104 504 451 HOH HOH D . 
T 5 HOH 105 505 473 HOH HOH D . 
T 5 HOH 106 506 452 HOH HOH D . 
T 5 HOH 107 507 153 HOH HOH D . 
T 5 HOH 108 508 488 HOH HOH D . 
T 5 HOH 109 509 215 HOH HOH D . 
T 5 HOH 110 510 381 HOH HOH D . 
T 5 HOH 111 511 527 HOH HOH D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLU 44  ? CG  ? A GLU 46  CG  
2  1 Y 1 A GLU 44  ? CD  ? A GLU 46  CD  
3  1 Y 1 A GLU 44  ? OE1 ? A GLU 46  OE1 
4  1 Y 1 A GLU 44  ? OE2 ? A GLU 46  OE2 
5  1 Y 1 A GLU 123 ? CG  ? A GLU 125 CG  
6  1 Y 1 A GLU 123 ? CD  ? A GLU 125 CD  
7  1 Y 1 A GLU 123 ? OE1 ? A GLU 125 OE1 
8  1 Y 1 A GLU 123 ? OE2 ? A GLU 125 OE2 
9  1 Y 1 D ARG 235 ? CG  ? D ARG 237 CG  
10 1 Y 1 D ARG 235 ? CD  ? D ARG 237 CD  
11 1 Y 1 D ARG 235 ? NE  ? D ARG 237 NE  
12 1 Y 1 D ARG 235 ? CZ  ? D ARG 237 CZ  
13 1 Y 1 D ARG 235 ? NH1 ? D ARG 237 NH1 
14 1 Y 1 D ARG 235 ? NH2 ? D ARG 237 NH2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.20.1_4487 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? .           2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? DENZO    ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.20.1_4487 4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   111.250 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9CA3 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     71.030 
_cell.length_a_esd                 ? 
_cell.length_b                     112.961 
_cell.length_b_esd                 ? 
_cell.length_c                     83.338 
_cell.length_c_esd                 ? 
_cell.volume                       623207.966 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9CA3 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            'P 2yb' 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9CA3 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.43 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          49.44 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '8% Tacsimate pH 6.0, 20% PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            289 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2024-04-24 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97946 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRL BEAMLINE BL9-2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97946 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL9-2 
_diffrn_source.pdbx_synchrotron_site       SSRL 
# 
_reflns.B_iso_Wilson_estimate                          31.95 
_reflns.entry_id                                       9CA3 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.89 
_reflns.d_resolution_low                               50.00 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     94295 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           96.6 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          4.1 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               0.988 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.173 
_reflns.pdbx_Rpim_I_all                                0.066 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       612990 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.977 
_reflns.pdbx_CC_star                                   0.994 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.160 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
1.89 1.92  ? ? ? ? ? ? 4163 ? ? ? ? ? ? ? ? ? ? ? 5.8 0.661 ? ? 1.186 0.462 ? 1  1 0.670 0.896 ? 85.2 ? 1.089 ? ? ? ? ? ? ? ? ? 
1.92 1.96  ? ? ? ? ? ? 4296 ? ? ? ? ? ? ? ? ? ? ? 5.9 0.669 ? ? 1.113 0.432 ? 2  1 0.699 0.907 ? 88.5 ? 1.023 ? ? ? ? ? ? ? ? ? 
1.96 2.00  ? ? ? ? ? ? 4400 ? ? ? ? ? ? ? ? ? ? ? 5.9 0.697 ? ? 0.998 0.387 ? 3  1 0.749 0.926 ? 90.8 ? 0.917 ? ? ? ? ? ? ? ? ? 
2.00 2.04  ? ? ? ? ? ? 4579 ? ? ? ? ? ? ? ? ? ? ? 5.9 0.710 ? ? 0.894 0.346 ? 4  1 0.783 0.937 ? 94.0 ? 0.822 ? ? ? ? ? ? ? ? ? 
2.04 2.08  ? ? ? ? ? ? 4726 ? ? ? ? ? ? ? ? ? ? ? 5.9 0.730 ? ? 0.762 0.296 ? 5  1 0.847 0.958 ? 97.2 ? 0.700 ? ? ? ? ? ? ? ? ? 
2.08 2.13  ? ? ? ? ? ? 4767 ? ? ? ? ? ? ? ? ? ? ? 6.0 0.758 ? ? 0.689 0.270 ? 6  1 0.849 0.958 ? 97.8 ? 0.632 ? ? ? ? ? ? ? ? ? 
2.13 2.18  ? ? ? ? ? ? 4637 ? ? ? ? ? ? ? ? ? ? ? 5.8 0.808 ? ? 0.596 0.239 ? 7  1 0.884 0.969 ? 95.3 ? 0.544 ? ? ? ? ? ? ? ? ? 
2.18 2.24  ? ? ? ? ? ? 4791 ? ? ? ? ? ? ? ? ? ? ? 6.6 0.804 ? ? 0.501 0.190 ? 8  1 0.923 0.980 ? 98.6 ? 0.463 ? ? ? ? ? ? ? ? ? 
2.24 2.31  ? ? ? ? ? ? 4817 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.874 ? ? 0.433 0.161 ? 9  1 0.940 0.984 ? 98.7 ? 0.401 ? ? ? ? ? ? ? ? ? 
2.31 2.38  ? ? ? ? ? ? 4786 ? ? ? ? ? ? ? ? ? ? ? 6.9 0.933 ? ? 0.381 0.142 ? 10 1 0.949 0.987 ? 98.6 ? 0.353 ? ? ? ? ? ? ? ? ? 
2.38 2.47  ? ? ? ? ? ? 4827 ? ? ? ? ? ? ? ? ? ? ? 6.8 0.974 ? ? 0.329 0.123 ? 11 1 0.960 0.990 ? 98.8 ? 0.304 ? ? ? ? ? ? ? ? ? 
2.47 2.57  ? ? ? ? ? ? 4824 ? ? ? ? ? ? ? ? ? ? ? 6.8 1.030 ? ? 0.297 0.111 ? 12 1 0.967 0.991 ? 99.1 ? 0.274 ? ? ? ? ? ? ? ? ? 
2.57 2.68  ? ? ? ? ? ? 4837 ? ? ? ? ? ? ? ? ? ? ? 6.7 1.054 ? ? 0.248 0.094 ? 13 1 0.971 0.993 ? 99.3 ? 0.229 ? ? ? ? ? ? ? ? ? 
2.68 2.82  ? ? ? ? ? ? 4729 ? ? ? ? ? ? ? ? ? ? ? 6.3 1.160 ? ? 0.224 0.089 ? 14 1 0.971 0.993 ? 96.5 ? 0.205 ? ? ? ? ? ? ? ? ? 
2.82 3.00  ? ? ? ? ? ? 4815 ? ? ? ? ? ? ? ? ? ? ? 7.0 1.226 ? ? 0.194 0.072 ? 15 1 0.980 0.995 ? 99.3 ? 0.180 ? ? ? ? ? ? ? ? ? 
3.00 3.23  ? ? ? ? ? ? 4893 ? ? ? ? ? ? ? ? ? ? ? 7.1 1.227 ? ? 0.169 0.063 ? 16 1 0.982 0.995 ? 99.4 ? 0.157 ? ? ? ? ? ? ? ? ? 
3.23 3.56  ? ? ? ? ? ? 4836 ? ? ? ? ? ? ? ? ? ? ? 7.0 1.278 ? ? 0.144 0.054 ? 17 1 0.985 0.996 ? 99.3 ? 0.134 ? ? ? ? ? ? ? ? ? 
3.56 4.07  ? ? ? ? ? ? 4779 ? ? ? ? ? ? ? ? ? ? ? 6.6 1.284 ? ? 0.136 0.052 ? 18 1 0.985 0.996 ? 97.7 ? 0.125 ? ? ? ? ? ? ? ? ? 
4.07 5.13  ? ? ? ? ? ? 4893 ? ? ? ? ? ? ? ? ? ? ? 7.0 1.154 ? ? 0.120 0.045 ? 19 1 0.990 0.998 ? 98.9 ? 0.112 ? ? ? ? ? ? ? ? ? 
5.13 50.00 ? ? ? ? ? ? 4900 ? ? ? ? ? ? ? ? ? ? ? 6.8 1.294 ? ? 0.134 0.051 ? 20 1 0.988 0.997 ? 98.3 ? 0.124 ? ? ? ? ? ? ? ? ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               39.17 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9CA3 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.89 
_refine.ls_d_res_low                             43.24 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     94052 
_refine.ls_number_reflns_R_free                  1991 
_refine.ls_number_reflns_R_work                  92061 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    95.76 
_refine.ls_percent_reflns_R_free                 2.12 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1942 
_refine.ls_R_factor_R_free                       0.2409 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1933 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 29.9525 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2558 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.89 
_refine_hist.d_res_low                        43.24 
_refine_hist.number_atoms_solvent             520 
_refine_hist.number_atoms_total               8985 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        8221 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         244 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0094 ? 8697  ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.1058 ? 11874 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0535 ? 1243  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0093 ? 1547  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 9.5518 ? 1186  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.89 1.94  . . 109 5343 77.55 . . . . 0.3656 . . . . . . . . . . . 0.4572 
'X-RAY DIFFRACTION' 1.94 1.99  . . 146 6104 89.44 . . . . 0.3330 . . . . . . . . . . . 0.3372 
'X-RAY DIFFRACTION' 1.99 2.05  . . 136 6429 93.99 . . . . 0.3011 . . . . . . . . . . . 0.3019 
'X-RAY DIFFRACTION' 2.05 2.11  . . 145 6631 97.23 . . . . 0.2763 . . . . . . . . . . . 0.3127 
'X-RAY DIFFRACTION' 2.11 2.19  . . 133 6571 95.77 . . . . 0.2449 . . . . . . . . . . . 0.3300 
'X-RAY DIFFRACTION' 2.19 2.28  . . 146 6726 98.19 . . . . 0.2218 . . . . . . . . . . . 0.3089 
'X-RAY DIFFRACTION' 2.28 2.38  . . 145 6747 98.34 . . . . 0.2092 . . . . . . . . . . . 0.2545 
'X-RAY DIFFRACTION' 2.38 2.50  . . 146 6761 98.69 . . . . 0.1933 . . . . . . . . . . . 0.2594 
'X-RAY DIFFRACTION' 2.50 2.66  . . 148 6802 99.23 . . . . 0.1908 . . . . . . . . . . . 0.2315 
'X-RAY DIFFRACTION' 2.66 2.87  . . 148 6662 97.13 . . . . 0.1848 . . . . . . . . . . . 0.2305 
'X-RAY DIFFRACTION' 2.87 3.15  . . 148 6799 99.33 . . . . 0.1880 . . . . . . . . . . . 0.2417 
'X-RAY DIFFRACTION' 3.15 3.61  . . 145 6859 99.35 . . . . 0.1799 . . . . . . . . . . . 0.2157 
'X-RAY DIFFRACTION' 3.61 4.55  . . 148 6744 97.81 . . . . 0.1584 . . . . . . . . . . . 0.2090 
'X-RAY DIFFRACTION' 4.55 43.24 . . 148 6883 98.57 . . . . 0.1707 . . . . . . . . . . . 0.2123 
# 
_struct.entry_id                     9CA3 
_struct.title                        
'Crystal structure of MarE C280S in complex with cyanide bound heme and its native substrate, beta-methyl-L-tryptophan' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9CA3 
_struct_keywords.text            'heme-dependent aromatic oxygenase, HDAO, heme, cyanide, beta-methyl-L-tryptophan, OXIDOREDUCTASE' 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 3 ? 
G N N 4 ? 
H N N 2 ? 
I N N 3 ? 
J N N 4 ? 
K N N 2 ? 
L N N 3 ? 
M N N 4 ? 
N N N 2 ? 
O N N 3 ? 
P N N 4 ? 
Q N N 5 ? 
R N N 5 ? 
S N N 5 ? 
T N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    X2D878_9ACTN 
_struct_ref.pdbx_db_accession          X2D878 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKRSLNPDEPNALLSYDFDRGSNYENVLHLTDALGALVPESETEHPDQRFFQVTHLITEYAWVQVHYELRRAIGHLDEDR
YHQAVRMFDRATGLSEVTVQAVRLLTDHLPQHSLLMMRNALPEDATGLDSPGYRNLRRVARPVWKAYEQAVERAGLSLQD
VIAQQDDGYDGPRSGGSQSLALVREAMLRLDGSVLGWKQHHLIMVWSQLGGQPGLRKGNEEGDDGLELPQSLGGRSLATL
EARSQLALFPELWRAAEDAYWLLGTRHDTDAPVRGGGNGCPVQH
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9CA3 A 3 ? 286 ? X2D878 1 ? 284 ? 1 284 
2 1 9CA3 B 3 ? 286 ? X2D878 1 ? 284 ? 1 284 
3 1 9CA3 C 3 ? 286 ? X2D878 1 ? 284 ? 1 284 
4 1 9CA3 D 3 ? 286 ? X2D878 1 ? 284 ? 1 284 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9CA3 GLY A 1   ? UNP X2D878 ?   ?   'expression tag'      -1  1  
1 9CA3 HIS A 2   ? UNP X2D878 ?   ?   'expression tag'      0   2  
1 9CA3 SER A 282 ? UNP X2D878 CYS 280 'engineered mutation' 280 3  
2 9CA3 GLY B 1   ? UNP X2D878 ?   ?   'expression tag'      -1  4  
2 9CA3 HIS B 2   ? UNP X2D878 ?   ?   'expression tag'      0   5  
2 9CA3 SER B 282 ? UNP X2D878 CYS 280 'engineered mutation' 280 6  
3 9CA3 GLY C 1   ? UNP X2D878 ?   ?   'expression tag'      -1  7  
3 9CA3 HIS C 2   ? UNP X2D878 ?   ?   'expression tag'      0   8  
3 9CA3 SER C 282 ? UNP X2D878 CYS 280 'engineered mutation' 280 9  
4 9CA3 GLY D 1   ? UNP X2D878 ?   ?   'expression tag'      -1  10 
4 9CA3 HIS D 2   ? UNP X2D878 ?   ?   'expression tag'      0   11 
4 9CA3 SER D 282 ? UNP X2D878 CYS 280 'engineered mutation' 280 12 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 33680 ? 
1 MORE         -205  ? 
1 'SSA (A^2)'  32040 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASN A 13  ? SER A 17  ? ASN A 11  SER A 15  5 ? 5  
HELX_P HELX_P2  AA2 SER A 24  ? HIS A 31  ? SER A 22  HIS A 29  1 ? 8  
HELX_P HELX_P3  AA3 HIS A 31  ? GLY A 37  ? HIS A 29  GLY A 35  1 ? 7  
HELX_P HELX_P4  AA4 PRO A 41  ? THR A 45  ? PRO A 39  THR A 43  5 ? 5  
HELX_P HELX_P5  AA5 ASP A 49  ? GLU A 80  ? ASP A 47  GLU A 78  1 ? 32 
HELX_P HELX_P6  AA6 ARG A 82  ? LEU A 111 ? ARG A 80  LEU A 109 1 ? 30 
HELX_P HELX_P7  AA7 PRO A 112 ? LEU A 123 ? PRO A 110 LEU A 121 1 ? 12 
HELX_P HELX_P8  AA8 THR A 128 ? ASP A 131 ? THR A 126 ASP A 129 5 ? 4  
HELX_P HELX_P9  AA9 SER A 132 ? ALA A 156 ? SER A 130 ALA A 154 1 ? 25 
HELX_P HELX_P10 AB1 SER A 159 ? GLN A 166 ? SER A 157 GLN A 164 1 ? 8  
HELX_P HELX_P11 AB2 SER A 176 ? LEU A 211 ? SER A 174 LEU A 209 1 ? 36 
HELX_P HELX_P12 AB3 GLN A 214 ? ARG A 218 ? GLN A 212 ARG A 216 5 ? 5  
HELX_P HELX_P13 AB4 SER A 238 ? SER A 246 ? SER A 236 SER A 244 1 ? 9  
HELX_P HELX_P14 AB5 PHE A 251 ? GLY A 266 ? PHE A 249 GLY A 264 1 ? 16 
HELX_P HELX_P15 AB6 ASN B 13  ? SER B 17  ? ASN B 11  SER B 15  5 ? 5  
HELX_P HELX_P16 AB7 SER B 24  ? HIS B 31  ? SER B 22  HIS B 29  1 ? 8  
HELX_P HELX_P17 AB8 HIS B 31  ? GLY B 37  ? HIS B 29  GLY B 35  1 ? 7  
HELX_P HELX_P18 AB9 PRO B 41  ? THR B 45  ? PRO B 39  THR B 43  5 ? 5  
HELX_P HELX_P19 AC1 ASP B 49  ? GLU B 80  ? ASP B 47  GLU B 78  1 ? 32 
HELX_P HELX_P20 AC2 ARG B 82  ? LEU B 111 ? ARG B 80  LEU B 109 1 ? 30 
HELX_P HELX_P21 AC3 PRO B 112 ? ASN B 121 ? PRO B 110 ASN B 119 1 ? 10 
HELX_P HELX_P22 AC4 THR B 128 ? ASP B 131 ? THR B 126 ASP B 129 5 ? 4  
HELX_P HELX_P23 AC5 SER B 132 ? ALA B 156 ? SER B 130 ALA B 154 1 ? 25 
HELX_P HELX_P24 AC6 SER B 159 ? GLN B 166 ? SER B 157 GLN B 164 1 ? 8  
HELX_P HELX_P25 AC7 SER B 176 ? LEU B 211 ? SER B 174 LEU B 209 1 ? 36 
HELX_P HELX_P26 AC8 SER B 238 ? SER B 246 ? SER B 236 SER B 244 1 ? 9  
HELX_P HELX_P27 AC9 PHE B 251 ? GLY B 266 ? PHE B 249 GLY B 264 1 ? 16 
HELX_P HELX_P28 AD1 ASN C 13  ? SER C 17  ? ASN C 11  SER C 15  5 ? 5  
HELX_P HELX_P29 AD2 SER C 24  ? HIS C 31  ? SER C 22  HIS C 29  1 ? 8  
HELX_P HELX_P30 AD3 HIS C 31  ? GLY C 37  ? HIS C 29  GLY C 35  1 ? 7  
HELX_P HELX_P31 AD4 PRO C 41  ? THR C 45  ? PRO C 39  THR C 43  5 ? 5  
HELX_P HELX_P32 AD5 ASP C 49  ? GLU C 80  ? ASP C 47  GLU C 78  1 ? 32 
HELX_P HELX_P33 AD6 ARG C 82  ? LEU C 111 ? ARG C 80  LEU C 109 1 ? 30 
HELX_P HELX_P34 AD7 PRO C 112 ? LEU C 123 ? PRO C 110 LEU C 121 1 ? 12 
HELX_P HELX_P35 AD8 THR C 128 ? ASP C 131 ? THR C 126 ASP C 129 5 ? 4  
HELX_P HELX_P36 AD9 SER C 132 ? ALA C 156 ? SER C 130 ALA C 154 1 ? 25 
HELX_P HELX_P37 AE1 SER C 159 ? GLN C 166 ? SER C 157 GLN C 164 1 ? 8  
HELX_P HELX_P38 AE2 SER C 176 ? GLY C 212 ? SER C 174 GLY C 210 1 ? 37 
HELX_P HELX_P39 AE3 GLN C 214 ? ARG C 218 ? GLN C 212 ARG C 216 5 ? 5  
HELX_P HELX_P40 AE4 SER C 238 ? SER C 246 ? SER C 236 SER C 244 1 ? 9  
HELX_P HELX_P41 AE5 PHE C 251 ? GLY C 266 ? PHE C 249 GLY C 264 1 ? 16 
HELX_P HELX_P42 AE6 ASN D 13  ? SER D 17  ? ASN D 11  SER D 15  5 ? 5  
HELX_P HELX_P43 AE7 SER D 24  ? HIS D 31  ? SER D 22  HIS D 29  1 ? 8  
HELX_P HELX_P44 AE8 HIS D 31  ? GLY D 37  ? HIS D 29  GLY D 35  1 ? 7  
HELX_P HELX_P45 AE9 PRO D 41  ? THR D 45  ? PRO D 39  THR D 43  5 ? 5  
HELX_P HELX_P46 AF1 ASP D 49  ? GLU D 80  ? ASP D 47  GLU D 78  1 ? 32 
HELX_P HELX_P47 AF2 ARG D 82  ? LEU D 111 ? ARG D 80  LEU D 109 1 ? 30 
HELX_P HELX_P48 AF3 PRO D 112 ? LEU D 123 ? PRO D 110 LEU D 121 1 ? 12 
HELX_P HELX_P49 AF4 THR D 128 ? ASP D 131 ? THR D 126 ASP D 129 5 ? 4  
HELX_P HELX_P50 AF5 SER D 132 ? ALA D 156 ? SER D 130 ALA D 154 1 ? 25 
HELX_P HELX_P51 AF6 SER D 159 ? GLN D 166 ? SER D 157 GLN D 164 1 ? 8  
HELX_P HELX_P52 AF7 SER D 176 ? LEU D 211 ? SER D 174 LEU D 209 1 ? 36 
HELX_P HELX_P53 AF8 SER D 238 ? SER D 246 ? SER D 236 SER D 244 1 ? 9  
HELX_P HELX_P54 AF9 PHE D 251 ? GLY D 266 ? PHE D 249 GLY D 264 1 ? 16 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A HIS 203 NE2 ? ? ? 1_555 E HEM . FE ? ? A HIS 201 A HEM 301 1_555 ? ? ? ? ? ? ? 2.298 ? ? 
metalc2 metalc ? ? B HIS 203 NE2 ? ? ? 1_555 H HEM . FE ? ? B HIS 201 B HEM 301 1_555 ? ? ? ? ? ? ? 2.282 ? ? 
metalc3 metalc ? ? C HIS 203 NE2 ? ? ? 1_555 K HEM . FE ? ? C HIS 201 C HEM 301 1_555 ? ? ? ? ? ? ? 2.240 ? ? 
metalc4 metalc ? ? D HIS 203 NE2 ? ? ? 1_555 N HEM . FE ? ? D HIS 201 D HEM 301 1_555 ? ? ? ? ? ? ? 2.277 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? A HIS 203 ? A HIS 201 ? 1_555 FE ? E HEM . ? A HEM 301 ? 1_555 NA ? E HEM . ? A HEM 301 ? 1_555 89.9  ? 
2  NE2 ? A HIS 203 ? A HIS 201 ? 1_555 FE ? E HEM . ? A HEM 301 ? 1_555 NB ? E HEM . ? A HEM 301 ? 1_555 83.1  ? 
3  NA  ? E HEM .   ? A HEM 301 ? 1_555 FE ? E HEM . ? A HEM 301 ? 1_555 NB ? E HEM . ? A HEM 301 ? 1_555 87.5  ? 
4  NE2 ? A HIS 203 ? A HIS 201 ? 1_555 FE ? E HEM . ? A HEM 301 ? 1_555 NC ? E HEM . ? A HEM 301 ? 1_555 86.3  ? 
5  NA  ? E HEM .   ? A HEM 301 ? 1_555 FE ? E HEM . ? A HEM 301 ? 1_555 NC ? E HEM . ? A HEM 301 ? 1_555 175.2 ? 
6  NB  ? E HEM .   ? A HEM 301 ? 1_555 FE ? E HEM . ? A HEM 301 ? 1_555 NC ? E HEM . ? A HEM 301 ? 1_555 89.1  ? 
7  NE2 ? A HIS 203 ? A HIS 201 ? 1_555 FE ? E HEM . ? A HEM 301 ? 1_555 ND ? E HEM . ? A HEM 301 ? 1_555 92.0  ? 
8  NA  ? E HEM .   ? A HEM 301 ? 1_555 FE ? E HEM . ? A HEM 301 ? 1_555 ND ? E HEM . ? A HEM 301 ? 1_555 92.0  ? 
9  NB  ? E HEM .   ? A HEM 301 ? 1_555 FE ? E HEM . ? A HEM 301 ? 1_555 ND ? E HEM . ? A HEM 301 ? 1_555 175.1 ? 
10 NC  ? E HEM .   ? A HEM 301 ? 1_555 FE ? E HEM . ? A HEM 301 ? 1_555 ND ? E HEM . ? A HEM 301 ? 1_555 91.2  ? 
11 NE2 ? B HIS 203 ? B HIS 201 ? 1_555 FE ? H HEM . ? B HEM 301 ? 1_555 NA ? H HEM . ? B HEM 301 ? 1_555 90.2  ? 
12 NE2 ? B HIS 203 ? B HIS 201 ? 1_555 FE ? H HEM . ? B HEM 301 ? 1_555 NB ? H HEM . ? B HEM 301 ? 1_555 96.9  ? 
13 NA  ? H HEM .   ? B HEM 301 ? 1_555 FE ? H HEM . ? B HEM 301 ? 1_555 NB ? H HEM . ? B HEM 301 ? 1_555 85.5  ? 
14 NE2 ? B HIS 203 ? B HIS 201 ? 1_555 FE ? H HEM . ? B HEM 301 ? 1_555 NC ? H HEM . ? B HEM 301 ? 1_555 92.1  ? 
15 NA  ? H HEM .   ? B HEM 301 ? 1_555 FE ? H HEM . ? B HEM 301 ? 1_555 NC ? H HEM . ? B HEM 301 ? 1_555 177.4 ? 
16 NB  ? H HEM .   ? B HEM 301 ? 1_555 FE ? H HEM . ? B HEM 301 ? 1_555 NC ? H HEM . ? B HEM 301 ? 1_555 93.2  ? 
17 NE2 ? B HIS 203 ? B HIS 201 ? 1_555 FE ? H HEM . ? B HEM 301 ? 1_555 ND ? H HEM . ? B HEM 301 ? 1_555 85.6  ? 
18 NA  ? H HEM .   ? B HEM 301 ? 1_555 FE ? H HEM . ? B HEM 301 ? 1_555 ND ? H HEM . ? B HEM 301 ? 1_555 93.5  ? 
19 NB  ? H HEM .   ? B HEM 301 ? 1_555 FE ? H HEM . ? B HEM 301 ? 1_555 ND ? H HEM . ? B HEM 301 ? 1_555 177.3 ? 
20 NC  ? H HEM .   ? B HEM 301 ? 1_555 FE ? H HEM . ? B HEM 301 ? 1_555 ND ? H HEM . ? B HEM 301 ? 1_555 87.8  ? 
21 NE2 ? C HIS 203 ? C HIS 201 ? 1_555 FE ? K HEM . ? C HEM 301 ? 1_555 NA ? K HEM . ? C HEM 301 ? 1_555 92.6  ? 
22 NE2 ? C HIS 203 ? C HIS 201 ? 1_555 FE ? K HEM . ? C HEM 301 ? 1_555 NB ? K HEM . ? C HEM 301 ? 1_555 87.8  ? 
23 NA  ? K HEM .   ? C HEM 301 ? 1_555 FE ? K HEM . ? C HEM 301 ? 1_555 NB ? K HEM . ? C HEM 301 ? 1_555 88.8  ? 
24 NE2 ? C HIS 203 ? C HIS 201 ? 1_555 FE ? K HEM . ? C HEM 301 ? 1_555 NC ? K HEM . ? C HEM 301 ? 1_555 89.1  ? 
25 NA  ? K HEM .   ? C HEM 301 ? 1_555 FE ? K HEM . ? C HEM 301 ? 1_555 NC ? K HEM . ? C HEM 301 ? 1_555 177.2 ? 
26 NB  ? K HEM .   ? C HEM 301 ? 1_555 FE ? K HEM . ? C HEM 301 ? 1_555 NC ? K HEM . ? C HEM 301 ? 1_555 93.4  ? 
27 NE2 ? C HIS 203 ? C HIS 201 ? 1_555 FE ? K HEM . ? C HEM 301 ? 1_555 ND ? K HEM . ? C HEM 301 ? 1_555 93.7  ? 
28 NA  ? K HEM .   ? C HEM 301 ? 1_555 FE ? K HEM . ? C HEM 301 ? 1_555 ND ? K HEM . ? C HEM 301 ? 1_555 90.6  ? 
29 NB  ? K HEM .   ? C HEM 301 ? 1_555 FE ? K HEM . ? C HEM 301 ? 1_555 ND ? K HEM . ? C HEM 301 ? 1_555 178.4 ? 
30 NC  ? K HEM .   ? C HEM 301 ? 1_555 FE ? K HEM . ? C HEM 301 ? 1_555 ND ? K HEM . ? C HEM 301 ? 1_555 87.1  ? 
31 NE2 ? D HIS 203 ? D HIS 201 ? 1_555 FE ? N HEM . ? D HEM 301 ? 1_555 NA ? N HEM . ? D HEM 301 ? 1_555 90.1  ? 
32 NE2 ? D HIS 203 ? D HIS 201 ? 1_555 FE ? N HEM . ? D HEM 301 ? 1_555 NB ? N HEM . ? D HEM 301 ? 1_555 94.1  ? 
33 NA  ? N HEM .   ? D HEM 301 ? 1_555 FE ? N HEM . ? D HEM 301 ? 1_555 NB ? N HEM . ? D HEM 301 ? 1_555 87.4  ? 
34 NE2 ? D HIS 203 ? D HIS 201 ? 1_555 FE ? N HEM . ? D HEM 301 ? 1_555 NC ? N HEM . ? D HEM 301 ? 1_555 90.5  ? 
35 NA  ? N HEM .   ? D HEM 301 ? 1_555 FE ? N HEM . ? D HEM 301 ? 1_555 NC ? N HEM . ? D HEM 301 ? 1_555 176.8 ? 
36 NB  ? N HEM .   ? D HEM 301 ? 1_555 FE ? N HEM . ? D HEM 301 ? 1_555 NC ? N HEM . ? D HEM 301 ? 1_555 89.4  ? 
37 NE2 ? D HIS 203 ? D HIS 201 ? 1_555 FE ? N HEM . ? D HEM 301 ? 1_555 ND ? N HEM . ? D HEM 301 ? 1_555 87.5  ? 
38 NA  ? N HEM .   ? D HEM 301 ? 1_555 FE ? N HEM . ? D HEM 301 ? 1_555 ND ? N HEM . ? D HEM 301 ? 1_555 93.9  ? 
39 NB  ? N HEM .   ? D HEM 301 ? 1_555 FE ? N HEM . ? D HEM 301 ? 1_555 ND ? N HEM . ? D HEM 301 ? 1_555 177.9 ? 
40 NC  ? N HEM .   ? D HEM 301 ? 1_555 FE ? N HEM . ? D HEM 301 ? 1_555 ND ? N HEM . ? D HEM 301 ? 1_555 89.2  ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG A 5  ? SER A 6  ? ARG A 3  SER A 4  
AA1 2 ASP A 19 ? PHE A 20 ? ASP A 17 PHE A 18 
AA2 1 ARG B 5  ? SER B 6  ? ARG B 3  SER B 4  
AA2 2 ASP B 19 ? PHE B 20 ? ASP B 17 PHE B 18 
AA3 1 ARG C 5  ? SER C 6  ? ARG C 3  SER C 4  
AA3 2 ASP C 19 ? PHE C 20 ? ASP C 17 PHE C 18 
AA4 1 ARG D 5  ? SER D 6  ? ARG D 3  SER D 4  
AA4 2 ASP D 19 ? PHE D 20 ? ASP D 17 PHE D 18 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ARG A 5 ? N ARG A 3 O PHE A 20 ? O PHE A 18 
AA2 1 2 N ARG B 5 ? N ARG B 3 O PHE B 20 ? O PHE B 18 
AA3 1 2 N ARG C 5 ? N ARG C 3 O PHE C 20 ? O PHE C 18 
AA4 1 2 N ARG D 5 ? N ARG D 3 O PHE D 20 ? O PHE D 18 
# 
_pdbx_entry_details.entry_id                   9CA3 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 NH2 D ARG 243 ? ? O2A D HEM 301 ? ? 1.30 
2  1 NH2 B ARG 266 ? ? O   C LEU 121 ? ? 1.92 
3  1 O   B LEU 121 ? ? NH2 C ARG 266 ? ? 1.99 
4  1 O   B HOH 542 ? ? O   C HOH 565 ? ? 2.10 
5  1 O   B HOH 535 ? ? O   C HOH 560 ? ? 2.11 
6  1 FE  C HEM 301 ? ? C   C CYN 302 ? ? 2.11 
7  1 FE  A HEM 301 ? ? C   A CYN 302 ? ? 2.12 
8  1 FE  D HEM 301 ? ? C   D CYN 302 ? ? 2.12 
9  1 FE  B HEM 301 ? ? C   B CYN 302 ? ? 2.12 
10 1 NZ  C LYS 2   ? ? O   C HOH 401 ? ? 2.14 
11 1 NH1 B ARG 141 ? ? OE2 B GLU 251 ? ? 2.15 
12 1 O   C HOH 513 ? ? O   C HOH 557 ? ? 2.16 
13 1 OH  C TYR 16  ? ? O   C HOH 402 ? ? 2.17 
14 1 O   A HOH 429 ? ? O   C HOH 462 ? ? 2.17 
15 1 O   D ALA 238 ? ? O   D HOH 401 ? ? 2.18 
16 1 OE1 B GLN 245 ? ? O   B HOH 401 ? ? 2.18 
17 1 OH  A TYR 16  ? ? O   A HOH 401 ? ? 2.19 
18 1 O   C LEU 248 ? ? O   C HOH 403 ? ? 2.19 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA C MET 204 ? ? CB C MET 204 ? ? CG  C MET 204 ? ? 127.33 113.30 14.03  1.70 N 
2 1 CG C MET 204 ? ? SD C MET 204 ? ? CE  C MET 204 ? ? 89.88  100.20 -10.32 1.60 N 
3 1 CB D LEU 252 ? ? CG D LEU 252 ? ? CD2 D LEU 252 ? ? 100.21 111.00 -10.79 1.70 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LEU A 232 ? ? -69.38  5.64   
2 1 ASN B 6   ? ? -144.76 51.58  
3 1 ASP B 124 ? ? -113.43 54.26  
4 1 LYS D 2   ? ? 176.54  169.63 
5 1 GLU D 9   ? ? -35.15  122.70 
6 1 PRO D 10  ? ? -55.34  -74.18 
7 1 LEU D 232 ? ? -58.98  -6.86  
8 1 ARG D 266 ? ? -152.27 46.47  
9 1 ASP D 268 ? ? -142.29 42.65  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z       
2 -x,y+1/2,-z 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      C 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       566 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   6.21 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A GLY -1  ? A GLY 1   
2   1 Y 1 A HIS 0   ? A HIS 2   
3   1 Y 1 A LYS 217 ? A LYS 219 
4   1 Y 1 A GLY 218 ? A GLY 220 
5   1 Y 1 A ASN 219 ? A ASN 221 
6   1 Y 1 A GLU 220 ? A GLU 222 
7   1 Y 1 A GLU 221 ? A GLU 223 
8   1 Y 1 A GLY 222 ? A GLY 224 
9   1 Y 1 A ASP 223 ? A ASP 225 
10  1 Y 1 A ASP 224 ? A ASP 226 
11  1 Y 1 A GLY 225 ? A GLY 227 
12  1 Y 1 A LEU 226 ? A LEU 228 
13  1 Y 1 A ARG 266 ? A ARG 268 
14  1 Y 1 A HIS 267 ? A HIS 269 
15  1 Y 1 A ASP 268 ? A ASP 270 
16  1 Y 1 A THR 269 ? A THR 271 
17  1 Y 1 A ASP 270 ? A ASP 272 
18  1 Y 1 A ALA 271 ? A ALA 273 
19  1 Y 1 A PRO 272 ? A PRO 274 
20  1 Y 1 A VAL 273 ? A VAL 275 
21  1 Y 1 A ARG 274 ? A ARG 276 
22  1 Y 1 A GLY 275 ? A GLY 277 
23  1 Y 1 A GLY 276 ? A GLY 278 
24  1 Y 1 A GLY 277 ? A GLY 279 
25  1 Y 1 A ASN 278 ? A ASN 280 
26  1 Y 1 A GLY 279 ? A GLY 281 
27  1 Y 1 A SER 280 ? A SER 282 
28  1 Y 1 A PRO 281 ? A PRO 283 
29  1 Y 1 A VAL 282 ? A VAL 284 
30  1 Y 1 A GLN 283 ? A GLN 285 
31  1 Y 1 A HIS 284 ? A HIS 286 
32  1 Y 1 B GLY -1  ? B GLY 1   
33  1 Y 1 B HIS 0   ? B HIS 2   
34  1 Y 1 B MET 1   ? B MET 3   
35  1 Y 1 B ARG 216 ? B ARG 218 
36  1 Y 1 B LYS 217 ? B LYS 219 
37  1 Y 1 B GLY 218 ? B GLY 220 
38  1 Y 1 B ASN 219 ? B ASN 221 
39  1 Y 1 B GLU 220 ? B GLU 222 
40  1 Y 1 B GLU 221 ? B GLU 223 
41  1 Y 1 B GLY 222 ? B GLY 224 
42  1 Y 1 B ASP 223 ? B ASP 225 
43  1 Y 1 B ASP 224 ? B ASP 226 
44  1 Y 1 B GLY 225 ? B GLY 227 
45  1 Y 1 B LEU 226 ? B LEU 228 
46  1 Y 1 B GLU 227 ? B GLU 229 
47  1 Y 1 B ARG 274 ? B ARG 276 
48  1 Y 1 B GLY 275 ? B GLY 277 
49  1 Y 1 B GLY 276 ? B GLY 278 
50  1 Y 1 B GLY 277 ? B GLY 279 
51  1 Y 1 B ASN 278 ? B ASN 280 
52  1 Y 1 B GLY 279 ? B GLY 281 
53  1 Y 1 B SER 280 ? B SER 282 
54  1 Y 1 B PRO 281 ? B PRO 283 
55  1 Y 1 B VAL 282 ? B VAL 284 
56  1 Y 1 B GLN 283 ? B GLN 285 
57  1 Y 1 B HIS 284 ? B HIS 286 
58  1 Y 1 C GLY -1  ? C GLY 1   
59  1 Y 1 C HIS 0   ? C HIS 2   
60  1 Y 1 C MET 1   ? C MET 3   
61  1 Y 1 C LYS 217 ? C LYS 219 
62  1 Y 1 C GLY 218 ? C GLY 220 
63  1 Y 1 C ASN 219 ? C ASN 221 
64  1 Y 1 C GLU 220 ? C GLU 222 
65  1 Y 1 C GLU 221 ? C GLU 223 
66  1 Y 1 C GLY 222 ? C GLY 224 
67  1 Y 1 C ASP 223 ? C ASP 225 
68  1 Y 1 C ASP 224 ? C ASP 226 
69  1 Y 1 C GLY 225 ? C GLY 227 
70  1 Y 1 C LEU 226 ? C LEU 228 
71  1 Y 1 C GLU 227 ? C GLU 229 
72  1 Y 1 C VAL 273 ? C VAL 275 
73  1 Y 1 C ARG 274 ? C ARG 276 
74  1 Y 1 C GLY 275 ? C GLY 277 
75  1 Y 1 C GLY 276 ? C GLY 278 
76  1 Y 1 C GLY 277 ? C GLY 279 
77  1 Y 1 C ASN 278 ? C ASN 280 
78  1 Y 1 C GLY 279 ? C GLY 281 
79  1 Y 1 C SER 280 ? C SER 282 
80  1 Y 1 C PRO 281 ? C PRO 283 
81  1 Y 1 C VAL 282 ? C VAL 284 
82  1 Y 1 C GLN 283 ? C GLN 285 
83  1 Y 1 C HIS 284 ? C HIS 286 
84  1 Y 1 D GLY -1  ? D GLY 1   
85  1 Y 1 D HIS 0   ? D HIS 2   
86  1 Y 1 D ARG 216 ? D ARG 218 
87  1 Y 1 D LYS 217 ? D LYS 219 
88  1 Y 1 D GLY 218 ? D GLY 220 
89  1 Y 1 D ASN 219 ? D ASN 221 
90  1 Y 1 D GLU 220 ? D GLU 222 
91  1 Y 1 D GLU 221 ? D GLU 223 
92  1 Y 1 D GLY 222 ? D GLY 224 
93  1 Y 1 D ASP 223 ? D ASP 225 
94  1 Y 1 D ASP 224 ? D ASP 226 
95  1 Y 1 D GLY 225 ? D GLY 227 
96  1 Y 1 D LEU 226 ? D LEU 228 
97  1 Y 1 D ASP 270 ? D ASP 272 
98  1 Y 1 D ALA 271 ? D ALA 273 
99  1 Y 1 D PRO 272 ? D PRO 274 
100 1 Y 1 D VAL 273 ? D VAL 275 
101 1 Y 1 D ARG 274 ? D ARG 276 
102 1 Y 1 D GLY 275 ? D GLY 277 
103 1 Y 1 D GLY 276 ? D GLY 278 
104 1 Y 1 D GLY 277 ? D GLY 279 
105 1 Y 1 D ASN 278 ? D ASN 280 
106 1 Y 1 D GLY 279 ? D GLY 281 
107 1 Y 1 D SER 280 ? D SER 282 
108 1 Y 1 D PRO 281 ? D PRO 283 
109 1 Y 1 D VAL 282 ? D VAL 284 
110 1 Y 1 D GLN 283 ? D GLN 285 
111 1 Y 1 D HIS 284 ? D HIS 286 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
78U OXT  O  N N 1   
78U C    C  N N 2   
78U O    O  N N 3   
78U CA   C  N S 4   
78U N    N  N N 5   
78U CB   C  N S 6   
78U CAG  C  N N 7   
78U CG   C  Y N 8   
78U CD2  C  Y N 9   
78U CE3  C  Y N 10  
78U CZ3  C  Y N 11  
78U CH2  C  Y N 12  
78U CZ2  C  Y N 13  
78U CE2  C  Y N 14  
78U NE1  N  Y N 15  
78U CD1  C  Y N 16  
78U H1   H  N N 17  
78U H2   H  N N 18  
78U H3   H  N N 19  
78U H4   H  N N 20  
78U H6   H  N N 21  
78U H7   H  N N 22  
78U H8   H  N N 23  
78U H9   H  N N 24  
78U H10  H  N N 25  
78U H11  H  N N 26  
78U H12  H  N N 27  
78U H13  H  N N 28  
78U H14  H  N N 29  
78U H15  H  N N 30  
ALA N    N  N N 31  
ALA CA   C  N S 32  
ALA C    C  N N 33  
ALA O    O  N N 34  
ALA CB   C  N N 35  
ALA OXT  O  N N 36  
ALA H    H  N N 37  
ALA H2   H  N N 38  
ALA HA   H  N N 39  
ALA HB1  H  N N 40  
ALA HB2  H  N N 41  
ALA HB3  H  N N 42  
ALA HXT  H  N N 43  
ARG N    N  N N 44  
ARG CA   C  N S 45  
ARG C    C  N N 46  
ARG O    O  N N 47  
ARG CB   C  N N 48  
ARG CG   C  N N 49  
ARG CD   C  N N 50  
ARG NE   N  N N 51  
ARG CZ   C  N N 52  
ARG NH1  N  N N 53  
ARG NH2  N  N N 54  
ARG OXT  O  N N 55  
ARG H    H  N N 56  
ARG H2   H  N N 57  
ARG HA   H  N N 58  
ARG HB2  H  N N 59  
ARG HB3  H  N N 60  
ARG HG2  H  N N 61  
ARG HG3  H  N N 62  
ARG HD2  H  N N 63  
ARG HD3  H  N N 64  
ARG HE   H  N N 65  
ARG HH11 H  N N 66  
ARG HH12 H  N N 67  
ARG HH21 H  N N 68  
ARG HH22 H  N N 69  
ARG HXT  H  N N 70  
ASN N    N  N N 71  
ASN CA   C  N S 72  
ASN C    C  N N 73  
ASN O    O  N N 74  
ASN CB   C  N N 75  
ASN CG   C  N N 76  
ASN OD1  O  N N 77  
ASN ND2  N  N N 78  
ASN OXT  O  N N 79  
ASN H    H  N N 80  
ASN H2   H  N N 81  
ASN HA   H  N N 82  
ASN HB2  H  N N 83  
ASN HB3  H  N N 84  
ASN HD21 H  N N 85  
ASN HD22 H  N N 86  
ASN HXT  H  N N 87  
ASP N    N  N N 88  
ASP CA   C  N S 89  
ASP C    C  N N 90  
ASP O    O  N N 91  
ASP CB   C  N N 92  
ASP CG   C  N N 93  
ASP OD1  O  N N 94  
ASP OD2  O  N N 95  
ASP OXT  O  N N 96  
ASP H    H  N N 97  
ASP H2   H  N N 98  
ASP HA   H  N N 99  
ASP HB2  H  N N 100 
ASP HB3  H  N N 101 
ASP HD2  H  N N 102 
ASP HXT  H  N N 103 
CYN C    C  N N 104 
CYN N    N  N N 105 
CYS N    N  N N 106 
CYS CA   C  N R 107 
CYS C    C  N N 108 
CYS O    O  N N 109 
CYS CB   C  N N 110 
CYS SG   S  N N 111 
CYS OXT  O  N N 112 
CYS H    H  N N 113 
CYS H2   H  N N 114 
CYS HA   H  N N 115 
CYS HB2  H  N N 116 
CYS HB3  H  N N 117 
CYS HG   H  N N 118 
CYS HXT  H  N N 119 
GLN N    N  N N 120 
GLN CA   C  N S 121 
GLN C    C  N N 122 
GLN O    O  N N 123 
GLN CB   C  N N 124 
GLN CG   C  N N 125 
GLN CD   C  N N 126 
GLN OE1  O  N N 127 
GLN NE2  N  N N 128 
GLN OXT  O  N N 129 
GLN H    H  N N 130 
GLN H2   H  N N 131 
GLN HA   H  N N 132 
GLN HB2  H  N N 133 
GLN HB3  H  N N 134 
GLN HG2  H  N N 135 
GLN HG3  H  N N 136 
GLN HE21 H  N N 137 
GLN HE22 H  N N 138 
GLN HXT  H  N N 139 
GLU N    N  N N 140 
GLU CA   C  N S 141 
GLU C    C  N N 142 
GLU O    O  N N 143 
GLU CB   C  N N 144 
GLU CG   C  N N 145 
GLU CD   C  N N 146 
GLU OE1  O  N N 147 
GLU OE2  O  N N 148 
GLU OXT  O  N N 149 
GLU H    H  N N 150 
GLU H2   H  N N 151 
GLU HA   H  N N 152 
GLU HB2  H  N N 153 
GLU HB3  H  N N 154 
GLU HG2  H  N N 155 
GLU HG3  H  N N 156 
GLU HE2  H  N N 157 
GLU HXT  H  N N 158 
GLY N    N  N N 159 
GLY CA   C  N N 160 
GLY C    C  N N 161 
GLY O    O  N N 162 
GLY OXT  O  N N 163 
GLY H    H  N N 164 
GLY H2   H  N N 165 
GLY HA2  H  N N 166 
GLY HA3  H  N N 167 
GLY HXT  H  N N 168 
HEM CHA  C  N N 169 
HEM CHB  C  N N 170 
HEM CHC  C  N N 171 
HEM CHD  C  N N 172 
HEM C1A  C  Y N 173 
HEM C2A  C  Y N 174 
HEM C3A  C  Y N 175 
HEM C4A  C  Y N 176 
HEM CMA  C  N N 177 
HEM CAA  C  N N 178 
HEM CBA  C  N N 179 
HEM CGA  C  N N 180 
HEM O1A  O  N N 181 
HEM O2A  O  N N 182 
HEM C1B  C  N N 183 
HEM C2B  C  N N 184 
HEM C3B  C  N N 185 
HEM C4B  C  N N 186 
HEM CMB  C  N N 187 
HEM CAB  C  N N 188 
HEM CBB  C  N N 189 
HEM C1C  C  Y N 190 
HEM C2C  C  Y N 191 
HEM C3C  C  Y N 192 
HEM C4C  C  Y N 193 
HEM CMC  C  N N 194 
HEM CAC  C  N N 195 
HEM CBC  C  N N 196 
HEM C1D  C  N N 197 
HEM C2D  C  N N 198 
HEM C3D  C  N N 199 
HEM C4D  C  N N 200 
HEM CMD  C  N N 201 
HEM CAD  C  N N 202 
HEM CBD  C  N N 203 
HEM CGD  C  N N 204 
HEM O1D  O  N N 205 
HEM O2D  O  N N 206 
HEM NA   N  Y N 207 
HEM NB   N  N N 208 
HEM NC   N  Y N 209 
HEM ND   N  N N 210 
HEM FE   FE N N 211 
HEM HHB  H  N N 212 
HEM HHC  H  N N 213 
HEM HHD  H  N N 214 
HEM HMA  H  N N 215 
HEM HMAA H  N N 216 
HEM HMAB H  N N 217 
HEM HAA  H  N N 218 
HEM HAAA H  N N 219 
HEM HBA  H  N N 220 
HEM HBAA H  N N 221 
HEM HMB  H  N N 222 
HEM HMBA H  N N 223 
HEM HMBB H  N N 224 
HEM HAB  H  N N 225 
HEM HBB  H  N N 226 
HEM HBBA H  N N 227 
HEM HMC  H  N N 228 
HEM HMCA H  N N 229 
HEM HMCB H  N N 230 
HEM HAC  H  N N 231 
HEM HBC  H  N N 232 
HEM HBCA H  N N 233 
HEM HMD  H  N N 234 
HEM HMDA H  N N 235 
HEM HMDB H  N N 236 
HEM HAD  H  N N 237 
HEM HADA H  N N 238 
HEM HBD  H  N N 239 
HEM HBDA H  N N 240 
HEM H2A  H  N N 241 
HEM H2D  H  N N 242 
HEM HHA  H  N N 243 
HIS N    N  N N 244 
HIS CA   C  N S 245 
HIS C    C  N N 246 
HIS O    O  N N 247 
HIS CB   C  N N 248 
HIS CG   C  Y N 249 
HIS ND1  N  Y N 250 
HIS CD2  C  Y N 251 
HIS CE1  C  Y N 252 
HIS NE2  N  Y N 253 
HIS OXT  O  N N 254 
HIS H    H  N N 255 
HIS H2   H  N N 256 
HIS HA   H  N N 257 
HIS HB2  H  N N 258 
HIS HB3  H  N N 259 
HIS HD1  H  N N 260 
HIS HD2  H  N N 261 
HIS HE1  H  N N 262 
HIS HE2  H  N N 263 
HIS HXT  H  N N 264 
HOH O    O  N N 265 
HOH H1   H  N N 266 
HOH H2   H  N N 267 
ILE N    N  N N 268 
ILE CA   C  N S 269 
ILE C    C  N N 270 
ILE O    O  N N 271 
ILE CB   C  N S 272 
ILE CG1  C  N N 273 
ILE CG2  C  N N 274 
ILE CD1  C  N N 275 
ILE OXT  O  N N 276 
ILE H    H  N N 277 
ILE H2   H  N N 278 
ILE HA   H  N N 279 
ILE HB   H  N N 280 
ILE HG12 H  N N 281 
ILE HG13 H  N N 282 
ILE HG21 H  N N 283 
ILE HG22 H  N N 284 
ILE HG23 H  N N 285 
ILE HD11 H  N N 286 
ILE HD12 H  N N 287 
ILE HD13 H  N N 288 
ILE HXT  H  N N 289 
LEU N    N  N N 290 
LEU CA   C  N S 291 
LEU C    C  N N 292 
LEU O    O  N N 293 
LEU CB   C  N N 294 
LEU CG   C  N N 295 
LEU CD1  C  N N 296 
LEU CD2  C  N N 297 
LEU OXT  O  N N 298 
LEU H    H  N N 299 
LEU H2   H  N N 300 
LEU HA   H  N N 301 
LEU HB2  H  N N 302 
LEU HB3  H  N N 303 
LEU HG   H  N N 304 
LEU HD11 H  N N 305 
LEU HD12 H  N N 306 
LEU HD13 H  N N 307 
LEU HD21 H  N N 308 
LEU HD22 H  N N 309 
LEU HD23 H  N N 310 
LEU HXT  H  N N 311 
LYS N    N  N N 312 
LYS CA   C  N S 313 
LYS C    C  N N 314 
LYS O    O  N N 315 
LYS CB   C  N N 316 
LYS CG   C  N N 317 
LYS CD   C  N N 318 
LYS CE   C  N N 319 
LYS NZ   N  N N 320 
LYS OXT  O  N N 321 
LYS H    H  N N 322 
LYS H2   H  N N 323 
LYS HA   H  N N 324 
LYS HB2  H  N N 325 
LYS HB3  H  N N 326 
LYS HG2  H  N N 327 
LYS HG3  H  N N 328 
LYS HD2  H  N N 329 
LYS HD3  H  N N 330 
LYS HE2  H  N N 331 
LYS HE3  H  N N 332 
LYS HZ1  H  N N 333 
LYS HZ2  H  N N 334 
LYS HZ3  H  N N 335 
LYS HXT  H  N N 336 
MET N    N  N N 337 
MET CA   C  N S 338 
MET C    C  N N 339 
MET O    O  N N 340 
MET CB   C  N N 341 
MET CG   C  N N 342 
MET SD   S  N N 343 
MET CE   C  N N 344 
MET OXT  O  N N 345 
MET H    H  N N 346 
MET H2   H  N N 347 
MET HA   H  N N 348 
MET HB2  H  N N 349 
MET HB3  H  N N 350 
MET HG2  H  N N 351 
MET HG3  H  N N 352 
MET HE1  H  N N 353 
MET HE2  H  N N 354 
MET HE3  H  N N 355 
MET HXT  H  N N 356 
PHE N    N  N N 357 
PHE CA   C  N S 358 
PHE C    C  N N 359 
PHE O    O  N N 360 
PHE CB   C  N N 361 
PHE CG   C  Y N 362 
PHE CD1  C  Y N 363 
PHE CD2  C  Y N 364 
PHE CE1  C  Y N 365 
PHE CE2  C  Y N 366 
PHE CZ   C  Y N 367 
PHE OXT  O  N N 368 
PHE H    H  N N 369 
PHE H2   H  N N 370 
PHE HA   H  N N 371 
PHE HB2  H  N N 372 
PHE HB3  H  N N 373 
PHE HD1  H  N N 374 
PHE HD2  H  N N 375 
PHE HE1  H  N N 376 
PHE HE2  H  N N 377 
PHE HZ   H  N N 378 
PHE HXT  H  N N 379 
PRO N    N  N N 380 
PRO CA   C  N S 381 
PRO C    C  N N 382 
PRO O    O  N N 383 
PRO CB   C  N N 384 
PRO CG   C  N N 385 
PRO CD   C  N N 386 
PRO OXT  O  N N 387 
PRO H    H  N N 388 
PRO HA   H  N N 389 
PRO HB2  H  N N 390 
PRO HB3  H  N N 391 
PRO HG2  H  N N 392 
PRO HG3  H  N N 393 
PRO HD2  H  N N 394 
PRO HD3  H  N N 395 
PRO HXT  H  N N 396 
SER N    N  N N 397 
SER CA   C  N S 398 
SER C    C  N N 399 
SER O    O  N N 400 
SER CB   C  N N 401 
SER OG   O  N N 402 
SER OXT  O  N N 403 
SER H    H  N N 404 
SER H2   H  N N 405 
SER HA   H  N N 406 
SER HB2  H  N N 407 
SER HB3  H  N N 408 
SER HG   H  N N 409 
SER HXT  H  N N 410 
THR N    N  N N 411 
THR CA   C  N S 412 
THR C    C  N N 413 
THR O    O  N N 414 
THR CB   C  N R 415 
THR OG1  O  N N 416 
THR CG2  C  N N 417 
THR OXT  O  N N 418 
THR H    H  N N 419 
THR H2   H  N N 420 
THR HA   H  N N 421 
THR HB   H  N N 422 
THR HG1  H  N N 423 
THR HG21 H  N N 424 
THR HG22 H  N N 425 
THR HG23 H  N N 426 
THR HXT  H  N N 427 
TRP N    N  N N 428 
TRP CA   C  N S 429 
TRP C    C  N N 430 
TRP O    O  N N 431 
TRP CB   C  N N 432 
TRP CG   C  Y N 433 
TRP CD1  C  Y N 434 
TRP CD2  C  Y N 435 
TRP NE1  N  Y N 436 
TRP CE2  C  Y N 437 
TRP CE3  C  Y N 438 
TRP CZ2  C  Y N 439 
TRP CZ3  C  Y N 440 
TRP CH2  C  Y N 441 
TRP OXT  O  N N 442 
TRP H    H  N N 443 
TRP H2   H  N N 444 
TRP HA   H  N N 445 
TRP HB2  H  N N 446 
TRP HB3  H  N N 447 
TRP HD1  H  N N 448 
TRP HE1  H  N N 449 
TRP HE3  H  N N 450 
TRP HZ2  H  N N 451 
TRP HZ3  H  N N 452 
TRP HH2  H  N N 453 
TRP HXT  H  N N 454 
TYR N    N  N N 455 
TYR CA   C  N S 456 
TYR C    C  N N 457 
TYR O    O  N N 458 
TYR CB   C  N N 459 
TYR CG   C  Y N 460 
TYR CD1  C  Y N 461 
TYR CD2  C  Y N 462 
TYR CE1  C  Y N 463 
TYR CE2  C  Y N 464 
TYR CZ   C  Y N 465 
TYR OH   O  N N 466 
TYR OXT  O  N N 467 
TYR H    H  N N 468 
TYR H2   H  N N 469 
TYR HA   H  N N 470 
TYR HB2  H  N N 471 
TYR HB3  H  N N 472 
TYR HD1  H  N N 473 
TYR HD2  H  N N 474 
TYR HE1  H  N N 475 
TYR HE2  H  N N 476 
TYR HH   H  N N 477 
TYR HXT  H  N N 478 
VAL N    N  N N 479 
VAL CA   C  N S 480 
VAL C    C  N N 481 
VAL O    O  N N 482 
VAL CB   C  N N 483 
VAL CG1  C  N N 484 
VAL CG2  C  N N 485 
VAL OXT  O  N N 486 
VAL H    H  N N 487 
VAL H2   H  N N 488 
VAL HA   H  N N 489 
VAL HB   H  N N 490 
VAL HG11 H  N N 491 
VAL HG12 H  N N 492 
VAL HG13 H  N N 493 
VAL HG21 H  N N 494 
VAL HG22 H  N N 495 
VAL HG23 H  N N 496 
VAL HXT  H  N N 497 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
78U O   C    doub N N 1   
78U C   OXT  sing N N 2   
78U C   CA   sing N N 3   
78U CA  CB   sing N N 4   
78U CA  N    sing N N 5   
78U CB  CAG  sing N N 6   
78U CB  CG   sing N N 7   
78U CD1 CG   doub Y N 8   
78U CD1 NE1  sing Y N 9   
78U CG  CD2  sing Y N 10  
78U NE1 CE2  sing Y N 11  
78U CD2 CE2  doub Y N 12  
78U CD2 CE3  sing Y N 13  
78U CE2 CZ2  sing Y N 14  
78U CE3 CZ3  doub Y N 15  
78U CZ2 CH2  doub Y N 16  
78U CZ3 CH2  sing Y N 17  
78U OXT H1   sing N N 18  
78U CA  H2   sing N N 19  
78U N   H3   sing N N 20  
78U N   H4   sing N N 21  
78U CB  H6   sing N N 22  
78U CAG H7   sing N N 23  
78U CAG H8   sing N N 24  
78U CAG H9   sing N N 25  
78U CE3 H10  sing N N 26  
78U CZ3 H11  sing N N 27  
78U CH2 H12  sing N N 28  
78U CZ2 H13  sing N N 29  
78U NE1 H14  sing N N 30  
78U CD1 H15  sing N N 31  
ALA N   CA   sing N N 32  
ALA N   H    sing N N 33  
ALA N   H2   sing N N 34  
ALA CA  C    sing N N 35  
ALA CA  CB   sing N N 36  
ALA CA  HA   sing N N 37  
ALA C   O    doub N N 38  
ALA C   OXT  sing N N 39  
ALA CB  HB1  sing N N 40  
ALA CB  HB2  sing N N 41  
ALA CB  HB3  sing N N 42  
ALA OXT HXT  sing N N 43  
ARG N   CA   sing N N 44  
ARG N   H    sing N N 45  
ARG N   H2   sing N N 46  
ARG CA  C    sing N N 47  
ARG CA  CB   sing N N 48  
ARG CA  HA   sing N N 49  
ARG C   O    doub N N 50  
ARG C   OXT  sing N N 51  
ARG CB  CG   sing N N 52  
ARG CB  HB2  sing N N 53  
ARG CB  HB3  sing N N 54  
ARG CG  CD   sing N N 55  
ARG CG  HG2  sing N N 56  
ARG CG  HG3  sing N N 57  
ARG CD  NE   sing N N 58  
ARG CD  HD2  sing N N 59  
ARG CD  HD3  sing N N 60  
ARG NE  CZ   sing N N 61  
ARG NE  HE   sing N N 62  
ARG CZ  NH1  sing N N 63  
ARG CZ  NH2  doub N N 64  
ARG NH1 HH11 sing N N 65  
ARG NH1 HH12 sing N N 66  
ARG NH2 HH21 sing N N 67  
ARG NH2 HH22 sing N N 68  
ARG OXT HXT  sing N N 69  
ASN N   CA   sing N N 70  
ASN N   H    sing N N 71  
ASN N   H2   sing N N 72  
ASN CA  C    sing N N 73  
ASN CA  CB   sing N N 74  
ASN CA  HA   sing N N 75  
ASN C   O    doub N N 76  
ASN C   OXT  sing N N 77  
ASN CB  CG   sing N N 78  
ASN CB  HB2  sing N N 79  
ASN CB  HB3  sing N N 80  
ASN CG  OD1  doub N N 81  
ASN CG  ND2  sing N N 82  
ASN ND2 HD21 sing N N 83  
ASN ND2 HD22 sing N N 84  
ASN OXT HXT  sing N N 85  
ASP N   CA   sing N N 86  
ASP N   H    sing N N 87  
ASP N   H2   sing N N 88  
ASP CA  C    sing N N 89  
ASP CA  CB   sing N N 90  
ASP CA  HA   sing N N 91  
ASP C   O    doub N N 92  
ASP C   OXT  sing N N 93  
ASP CB  CG   sing N N 94  
ASP CB  HB2  sing N N 95  
ASP CB  HB3  sing N N 96  
ASP CG  OD1  doub N N 97  
ASP CG  OD2  sing N N 98  
ASP OD2 HD2  sing N N 99  
ASP OXT HXT  sing N N 100 
CYN C   N    trip N N 101 
CYS N   CA   sing N N 102 
CYS N   H    sing N N 103 
CYS N   H2   sing N N 104 
CYS CA  C    sing N N 105 
CYS CA  CB   sing N N 106 
CYS CA  HA   sing N N 107 
CYS C   O    doub N N 108 
CYS C   OXT  sing N N 109 
CYS CB  SG   sing N N 110 
CYS CB  HB2  sing N N 111 
CYS CB  HB3  sing N N 112 
CYS SG  HG   sing N N 113 
CYS OXT HXT  sing N N 114 
GLN N   CA   sing N N 115 
GLN N   H    sing N N 116 
GLN N   H2   sing N N 117 
GLN CA  C    sing N N 118 
GLN CA  CB   sing N N 119 
GLN CA  HA   sing N N 120 
GLN C   O    doub N N 121 
GLN C   OXT  sing N N 122 
GLN CB  CG   sing N N 123 
GLN CB  HB2  sing N N 124 
GLN CB  HB3  sing N N 125 
GLN CG  CD   sing N N 126 
GLN CG  HG2  sing N N 127 
GLN CG  HG3  sing N N 128 
GLN CD  OE1  doub N N 129 
GLN CD  NE2  sing N N 130 
GLN NE2 HE21 sing N N 131 
GLN NE2 HE22 sing N N 132 
GLN OXT HXT  sing N N 133 
GLU N   CA   sing N N 134 
GLU N   H    sing N N 135 
GLU N   H2   sing N N 136 
GLU CA  C    sing N N 137 
GLU CA  CB   sing N N 138 
GLU CA  HA   sing N N 139 
GLU C   O    doub N N 140 
GLU C   OXT  sing N N 141 
GLU CB  CG   sing N N 142 
GLU CB  HB2  sing N N 143 
GLU CB  HB3  sing N N 144 
GLU CG  CD   sing N N 145 
GLU CG  HG2  sing N N 146 
GLU CG  HG3  sing N N 147 
GLU CD  OE1  doub N N 148 
GLU CD  OE2  sing N N 149 
GLU OE2 HE2  sing N N 150 
GLU OXT HXT  sing N N 151 
GLY N   CA   sing N N 152 
GLY N   H    sing N N 153 
GLY N   H2   sing N N 154 
GLY CA  C    sing N N 155 
GLY CA  HA2  sing N N 156 
GLY CA  HA3  sing N N 157 
GLY C   O    doub N N 158 
GLY C   OXT  sing N N 159 
GLY OXT HXT  sing N N 160 
HEM CHA C1A  sing N N 161 
HEM CHA C4D  doub N N 162 
HEM CHA HHA  sing N N 163 
HEM CHB C4A  sing N N 164 
HEM CHB C1B  doub N N 165 
HEM CHB HHB  sing N N 166 
HEM CHC C4B  sing N N 167 
HEM CHC C1C  doub N N 168 
HEM CHC HHC  sing N N 169 
HEM CHD C4C  doub N N 170 
HEM CHD C1D  sing N N 171 
HEM CHD HHD  sing N N 172 
HEM C1A C2A  doub Y N 173 
HEM C1A NA   sing Y N 174 
HEM C2A C3A  sing Y N 175 
HEM C2A CAA  sing N N 176 
HEM C3A C4A  doub Y N 177 
HEM C3A CMA  sing N N 178 
HEM C4A NA   sing Y N 179 
HEM CMA HMA  sing N N 180 
HEM CMA HMAA sing N N 181 
HEM CMA HMAB sing N N 182 
HEM CAA CBA  sing N N 183 
HEM CAA HAA  sing N N 184 
HEM CAA HAAA sing N N 185 
HEM CBA CGA  sing N N 186 
HEM CBA HBA  sing N N 187 
HEM CBA HBAA sing N N 188 
HEM CGA O1A  doub N N 189 
HEM CGA O2A  sing N N 190 
HEM C1B C2B  sing N N 191 
HEM C1B NB   sing N N 192 
HEM C2B C3B  doub N N 193 
HEM C2B CMB  sing N N 194 
HEM C3B C4B  sing N N 195 
HEM C3B CAB  sing N N 196 
HEM C4B NB   doub N N 197 
HEM CMB HMB  sing N N 198 
HEM CMB HMBA sing N N 199 
HEM CMB HMBB sing N N 200 
HEM CAB CBB  doub N N 201 
HEM CAB HAB  sing N N 202 
HEM CBB HBB  sing N N 203 
HEM CBB HBBA sing N N 204 
HEM C1C C2C  sing Y N 205 
HEM C1C NC   sing Y N 206 
HEM C2C C3C  doub Y N 207 
HEM C2C CMC  sing N N 208 
HEM C3C C4C  sing Y N 209 
HEM C3C CAC  sing N N 210 
HEM C4C NC   sing Y N 211 
HEM CMC HMC  sing N N 212 
HEM CMC HMCA sing N N 213 
HEM CMC HMCB sing N N 214 
HEM CAC CBC  doub N N 215 
HEM CAC HAC  sing N N 216 
HEM CBC HBC  sing N N 217 
HEM CBC HBCA sing N N 218 
HEM C1D C2D  sing N N 219 
HEM C1D ND   doub N N 220 
HEM C2D C3D  doub N N 221 
HEM C2D CMD  sing N N 222 
HEM C3D C4D  sing N N 223 
HEM C3D CAD  sing N N 224 
HEM C4D ND   sing N N 225 
HEM CMD HMD  sing N N 226 
HEM CMD HMDA sing N N 227 
HEM CMD HMDB sing N N 228 
HEM CAD CBD  sing N N 229 
HEM CAD HAD  sing N N 230 
HEM CAD HADA sing N N 231 
HEM CBD CGD  sing N N 232 
HEM CBD HBD  sing N N 233 
HEM CBD HBDA sing N N 234 
HEM CGD O1D  doub N N 235 
HEM CGD O2D  sing N N 236 
HEM O2A H2A  sing N N 237 
HEM O2D H2D  sing N N 238 
HEM FE  NA   sing N N 239 
HEM FE  NB   sing N N 240 
HEM FE  NC   sing N N 241 
HEM FE  ND   sing N N 242 
HIS N   CA   sing N N 243 
HIS N   H    sing N N 244 
HIS N   H2   sing N N 245 
HIS CA  C    sing N N 246 
HIS CA  CB   sing N N 247 
HIS CA  HA   sing N N 248 
HIS C   O    doub N N 249 
HIS C   OXT  sing N N 250 
HIS CB  CG   sing N N 251 
HIS CB  HB2  sing N N 252 
HIS CB  HB3  sing N N 253 
HIS CG  ND1  sing Y N 254 
HIS CG  CD2  doub Y N 255 
HIS ND1 CE1  doub Y N 256 
HIS ND1 HD1  sing N N 257 
HIS CD2 NE2  sing Y N 258 
HIS CD2 HD2  sing N N 259 
HIS CE1 NE2  sing Y N 260 
HIS CE1 HE1  sing N N 261 
HIS NE2 HE2  sing N N 262 
HIS OXT HXT  sing N N 263 
HOH O   H1   sing N N 264 
HOH O   H2   sing N N 265 
ILE N   CA   sing N N 266 
ILE N   H    sing N N 267 
ILE N   H2   sing N N 268 
ILE CA  C    sing N N 269 
ILE CA  CB   sing N N 270 
ILE CA  HA   sing N N 271 
ILE C   O    doub N N 272 
ILE C   OXT  sing N N 273 
ILE CB  CG1  sing N N 274 
ILE CB  CG2  sing N N 275 
ILE CB  HB   sing N N 276 
ILE CG1 CD1  sing N N 277 
ILE CG1 HG12 sing N N 278 
ILE CG1 HG13 sing N N 279 
ILE CG2 HG21 sing N N 280 
ILE CG2 HG22 sing N N 281 
ILE CG2 HG23 sing N N 282 
ILE CD1 HD11 sing N N 283 
ILE CD1 HD12 sing N N 284 
ILE CD1 HD13 sing N N 285 
ILE OXT HXT  sing N N 286 
LEU N   CA   sing N N 287 
LEU N   H    sing N N 288 
LEU N   H2   sing N N 289 
LEU CA  C    sing N N 290 
LEU CA  CB   sing N N 291 
LEU CA  HA   sing N N 292 
LEU C   O    doub N N 293 
LEU C   OXT  sing N N 294 
LEU CB  CG   sing N N 295 
LEU CB  HB2  sing N N 296 
LEU CB  HB3  sing N N 297 
LEU CG  CD1  sing N N 298 
LEU CG  CD2  sing N N 299 
LEU CG  HG   sing N N 300 
LEU CD1 HD11 sing N N 301 
LEU CD1 HD12 sing N N 302 
LEU CD1 HD13 sing N N 303 
LEU CD2 HD21 sing N N 304 
LEU CD2 HD22 sing N N 305 
LEU CD2 HD23 sing N N 306 
LEU OXT HXT  sing N N 307 
LYS N   CA   sing N N 308 
LYS N   H    sing N N 309 
LYS N   H2   sing N N 310 
LYS CA  C    sing N N 311 
LYS CA  CB   sing N N 312 
LYS CA  HA   sing N N 313 
LYS C   O    doub N N 314 
LYS C   OXT  sing N N 315 
LYS CB  CG   sing N N 316 
LYS CB  HB2  sing N N 317 
LYS CB  HB3  sing N N 318 
LYS CG  CD   sing N N 319 
LYS CG  HG2  sing N N 320 
LYS CG  HG3  sing N N 321 
LYS CD  CE   sing N N 322 
LYS CD  HD2  sing N N 323 
LYS CD  HD3  sing N N 324 
LYS CE  NZ   sing N N 325 
LYS CE  HE2  sing N N 326 
LYS CE  HE3  sing N N 327 
LYS NZ  HZ1  sing N N 328 
LYS NZ  HZ2  sing N N 329 
LYS NZ  HZ3  sing N N 330 
LYS OXT HXT  sing N N 331 
MET N   CA   sing N N 332 
MET N   H    sing N N 333 
MET N   H2   sing N N 334 
MET CA  C    sing N N 335 
MET CA  CB   sing N N 336 
MET CA  HA   sing N N 337 
MET C   O    doub N N 338 
MET C   OXT  sing N N 339 
MET CB  CG   sing N N 340 
MET CB  HB2  sing N N 341 
MET CB  HB3  sing N N 342 
MET CG  SD   sing N N 343 
MET CG  HG2  sing N N 344 
MET CG  HG3  sing N N 345 
MET SD  CE   sing N N 346 
MET CE  HE1  sing N N 347 
MET CE  HE2  sing N N 348 
MET CE  HE3  sing N N 349 
MET OXT HXT  sing N N 350 
PHE N   CA   sing N N 351 
PHE N   H    sing N N 352 
PHE N   H2   sing N N 353 
PHE CA  C    sing N N 354 
PHE CA  CB   sing N N 355 
PHE CA  HA   sing N N 356 
PHE C   O    doub N N 357 
PHE C   OXT  sing N N 358 
PHE CB  CG   sing N N 359 
PHE CB  HB2  sing N N 360 
PHE CB  HB3  sing N N 361 
PHE CG  CD1  doub Y N 362 
PHE CG  CD2  sing Y N 363 
PHE CD1 CE1  sing Y N 364 
PHE CD1 HD1  sing N N 365 
PHE CD2 CE2  doub Y N 366 
PHE CD2 HD2  sing N N 367 
PHE CE1 CZ   doub Y N 368 
PHE CE1 HE1  sing N N 369 
PHE CE2 CZ   sing Y N 370 
PHE CE2 HE2  sing N N 371 
PHE CZ  HZ   sing N N 372 
PHE OXT HXT  sing N N 373 
PRO N   CA   sing N N 374 
PRO N   CD   sing N N 375 
PRO N   H    sing N N 376 
PRO CA  C    sing N N 377 
PRO CA  CB   sing N N 378 
PRO CA  HA   sing N N 379 
PRO C   O    doub N N 380 
PRO C   OXT  sing N N 381 
PRO CB  CG   sing N N 382 
PRO CB  HB2  sing N N 383 
PRO CB  HB3  sing N N 384 
PRO CG  CD   sing N N 385 
PRO CG  HG2  sing N N 386 
PRO CG  HG3  sing N N 387 
PRO CD  HD2  sing N N 388 
PRO CD  HD3  sing N N 389 
PRO OXT HXT  sing N N 390 
SER N   CA   sing N N 391 
SER N   H    sing N N 392 
SER N   H2   sing N N 393 
SER CA  C    sing N N 394 
SER CA  CB   sing N N 395 
SER CA  HA   sing N N 396 
SER C   O    doub N N 397 
SER C   OXT  sing N N 398 
SER CB  OG   sing N N 399 
SER CB  HB2  sing N N 400 
SER CB  HB3  sing N N 401 
SER OG  HG   sing N N 402 
SER OXT HXT  sing N N 403 
THR N   CA   sing N N 404 
THR N   H    sing N N 405 
THR N   H2   sing N N 406 
THR CA  C    sing N N 407 
THR CA  CB   sing N N 408 
THR CA  HA   sing N N 409 
THR C   O    doub N N 410 
THR C   OXT  sing N N 411 
THR CB  OG1  sing N N 412 
THR CB  CG2  sing N N 413 
THR CB  HB   sing N N 414 
THR OG1 HG1  sing N N 415 
THR CG2 HG21 sing N N 416 
THR CG2 HG22 sing N N 417 
THR CG2 HG23 sing N N 418 
THR OXT HXT  sing N N 419 
TRP N   CA   sing N N 420 
TRP N   H    sing N N 421 
TRP N   H2   sing N N 422 
TRP CA  C    sing N N 423 
TRP CA  CB   sing N N 424 
TRP CA  HA   sing N N 425 
TRP C   O    doub N N 426 
TRP C   OXT  sing N N 427 
TRP CB  CG   sing N N 428 
TRP CB  HB2  sing N N 429 
TRP CB  HB3  sing N N 430 
TRP CG  CD1  doub Y N 431 
TRP CG  CD2  sing Y N 432 
TRP CD1 NE1  sing Y N 433 
TRP CD1 HD1  sing N N 434 
TRP CD2 CE2  doub Y N 435 
TRP CD2 CE3  sing Y N 436 
TRP NE1 CE2  sing Y N 437 
TRP NE1 HE1  sing N N 438 
TRP CE2 CZ2  sing Y N 439 
TRP CE3 CZ3  doub Y N 440 
TRP CE3 HE3  sing N N 441 
TRP CZ2 CH2  doub Y N 442 
TRP CZ2 HZ2  sing N N 443 
TRP CZ3 CH2  sing Y N 444 
TRP CZ3 HZ3  sing N N 445 
TRP CH2 HH2  sing N N 446 
TRP OXT HXT  sing N N 447 
TYR N   CA   sing N N 448 
TYR N   H    sing N N 449 
TYR N   H2   sing N N 450 
TYR CA  C    sing N N 451 
TYR CA  CB   sing N N 452 
TYR CA  HA   sing N N 453 
TYR C   O    doub N N 454 
TYR C   OXT  sing N N 455 
TYR CB  CG   sing N N 456 
TYR CB  HB2  sing N N 457 
TYR CB  HB3  sing N N 458 
TYR CG  CD1  doub Y N 459 
TYR CG  CD2  sing Y N 460 
TYR CD1 CE1  sing Y N 461 
TYR CD1 HD1  sing N N 462 
TYR CD2 CE2  doub Y N 463 
TYR CD2 HD2  sing N N 464 
TYR CE1 CZ   doub Y N 465 
TYR CE1 HE1  sing N N 466 
TYR CE2 CZ   sing Y N 467 
TYR CE2 HE2  sing N N 468 
TYR CZ  OH   sing N N 469 
TYR OH  HH   sing N N 470 
TYR OXT HXT  sing N N 471 
VAL N   CA   sing N N 472 
VAL N   H    sing N N 473 
VAL N   H2   sing N N 474 
VAL CA  C    sing N N 475 
VAL CA  CB   sing N N 476 
VAL CA  HA   sing N N 477 
VAL C   O    doub N N 478 
VAL C   OXT  sing N N 479 
VAL CB  CG1  sing N N 480 
VAL CB  CG2  sing N N 481 
VAL CB  HB   sing N N 482 
VAL CG1 HG11 sing N N 483 
VAL CG1 HG12 sing N N 484 
VAL CG1 HG13 sing N N 485 
VAL CG2 HG21 sing N N 486 
VAL CG2 HG22 sing N N 487 
VAL CG2 HG23 sing N N 488 
VAL OXT HXT  sing N N 489 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           R01GM108988 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 1 21 1' 
_space_group.name_Hall        'P 2yb' 
_space_group.IT_number        4 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9CA3 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.014079 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.005475 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.008853 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012875 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
FE ? ? 20.90327 4.99816 ? ? 2.55100  38.46870 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882  3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . MET A 1 3   ? 49.02393  -0.01492  -34.10337 1.000 54.06071 ? 1   MET A N   1 
ATOM   2    C  CA  . MET A 1 3   ? 48.57725  -1.37403  -33.80788 1.000 58.74229 ? 1   MET A CA  1 
ATOM   3    C  C   . MET A 1 3   ? 47.88608  -1.50603  -32.46279 1.000 56.60970 ? 1   MET A C   1 
ATOM   4    O  O   . MET A 1 3   ? 48.10357  -0.71623  -31.54488 1.000 57.60805 ? 1   MET A O   1 
ATOM   5    C  CB  . MET A 1 3   ? 49.74269  -2.35989  -33.86620 1.000 57.98183 ? 1   MET A CB  1 
ATOM   6    C  CG  . MET A 1 3   ? 49.89474  -3.07017  -35.20726 1.000 67.01802 ? 1   MET A CG  1 
ATOM   7    S  SD  . MET A 1 3   ? 51.59550  -3.43350  -35.62752 1.000 70.16679 ? 1   MET A SD  1 
ATOM   8    C  CE  . MET A 1 3   ? 52.28458  -1.81009  -35.39003 1.000 49.76362 ? 1   MET A CE  1 
ATOM   9    N  N   . LYS A 1 4   ? 47.06314  -2.54193  -32.37319 1.000 56.12821 ? 2   LYS A N   1 
ATOM   10   C  CA  . LYS A 1 4   ? 46.19448  -2.78611  -31.23507 1.000 55.65522 ? 2   LYS A CA  1 
ATOM   11   C  C   . LYS A 1 4   ? 46.95599  -3.47237  -30.10030 1.000 56.37620 ? 2   LYS A C   1 
ATOM   12   O  O   . LYS A 1 4   ? 47.99284  -4.11468  -30.29937 1.000 53.42439 ? 2   LYS A O   1 
ATOM   13   C  CB  . LYS A 1 4   ? 45.00695  -3.65539  -31.66080 1.000 51.95926 ? 2   LYS A CB  1 
ATOM   14   C  CG  . LYS A 1 4   ? 45.42651  -4.97227  -32.34085 1.000 58.73468 ? 2   LYS A CG  1 
ATOM   15   C  CD  . LYS A 1 4   ? 44.62065  -5.27188  -33.61253 1.000 62.42862 ? 2   LYS A CD  1 
ATOM   16   C  CE  . LYS A 1 4   ? 45.28446  -6.35012  -34.48231 1.000 61.17381 ? 2   LYS A CE  1 
ATOM   17   N  NZ  . LYS A 1 4   ? 45.03333  -6.14775  -35.94970 1.000 62.27370 ? 2   LYS A NZ  1 
ATOM   18   N  N   . ARG A 1 5   ? 46.42478  -3.30808  -28.89456 1.000 52.35691 ? 3   ARG A N   1 
ATOM   19   C  CA  . ARG A 1 5   ? 46.82035  -4.04756  -27.71037 1.000 51.17596 ? 3   ARG A CA  1 
ATOM   20   C  C   . ARG A 1 5   ? 45.65570  -4.94061  -27.30884 1.000 49.91580 ? 3   ARG A C   1 
ATOM   21   O  O   . ARG A 1 5   ? 44.50014  -4.67880  -27.65607 1.000 47.36607 ? 3   ARG A O   1 
ATOM   22   C  CB  . ARG A 1 5   ? 47.14238  -3.10658  -26.54543 1.000 50.77808 ? 3   ARG A CB  1 
ATOM   23   C  CG  . ARG A 1 5   ? 48.55966  -2.59486  -26.44681 1.000 52.50189 ? 3   ARG A CG  1 
ATOM   24   C  CD  . ARG A 1 5   ? 48.55569  -1.41851  -25.46566 1.000 53.52904 ? 3   ARG A CD  1 
ATOM   25   N  NE  . ARG A 1 5   ? 48.01230  -1.85198  -24.18233 1.000 55.70292 ? 3   ARG A NE  1 
ATOM   26   C  CZ  . ARG A 1 5   ? 47.47005  -1.06526  -23.26114 1.000 55.82118 ? 3   ARG A CZ  1 
ATOM   27   N  NH1 . ARG A 1 5   ? 47.33999  0.23919   -23.44627 1.000 52.96877 ? 3   ARG A NH1 1 
ATOM   28   N  NH2 . ARG A 1 5   ? 47.03281  -1.60755  -22.12506 1.000 58.52395 ? 3   ARG A NH2 1 
ATOM   29   N  N   . SER A 1 6   ? 45.95056  -5.98148  -26.54514 1.000 51.00216 ? 4   SER A N   1 
ATOM   30   C  CA  . SER A 1 6   ? 44.92198  -6.90402  -26.09663 1.000 48.77874 ? 4   SER A CA  1 
ATOM   31   C  C   . SER A 1 6   ? 44.68061  -6.72403  -24.60589 1.000 50.52508 ? 4   SER A C   1 
ATOM   32   O  O   . SER A 1 6   ? 45.62777  -6.69588  -23.81421 1.000 52.52362 ? 4   SER A O   1 
ATOM   33   C  CB  . SER A 1 6   ? 45.30717  -8.35075  -26.40336 1.000 50.43111 ? 4   SER A CB  1 
ATOM   34   O  OG  . SER A 1 6   ? 44.32400  -9.22586  -25.89446 1.000 47.63258 ? 4   SER A OG  1 
ATOM   35   N  N   . LEU A 1 7   ? 43.40989  -6.60518  -24.22418 1.000 49.63591 ? 5   LEU A N   1 
ATOM   36   C  CA  . LEU A 1 7   ? 43.08217  -6.61672  -22.80795 1.000 50.32142 ? 5   LEU A CA  1 
ATOM   37   C  C   . LEU A 1 7   ? 43.27097  -7.99738  -22.19609 1.000 53.75545 ? 5   LEU A C   1 
ATOM   38   O  O   . LEU A 1 7   ? 43.41455  -8.10873  -20.97174 1.000 54.35869 ? 5   LEU A O   1 
ATOM   39   C  CB  . LEU A 1 7   ? 41.64378  -6.14017  -22.59167 1.000 49.84860 ? 5   LEU A CB  1 
ATOM   40   C  CG  . LEU A 1 7   ? 41.48260  -4.74276  -21.99832 1.000 51.22104 ? 5   LEU A CG  1 
ATOM   41   C  CD1 . LEU A 1 7   ? 40.00405  -4.38419  -21.80740 1.000 49.57476 ? 5   LEU A CD1 1 
ATOM   42   C  CD2 . LEU A 1 7   ? 42.25770  -4.59140  -20.68231 1.000 53.23275 ? 5   LEU A CD2 1 
ATOM   43   N  N   . ASN A 1 8   ? 43.25693  -9.04787  -23.01568 1.000 50.31879 ? 6   ASN A N   1 
ATOM   44   C  CA  . ASN A 1 8   ? 43.41631  -10.42566 -22.55792 1.000 52.55149 ? 6   ASN A CA  1 
ATOM   45   C  C   . ASN A 1 8   ? 44.48824  -11.07602 -23.42591 1.000 52.12579 ? 6   ASN A C   1 
ATOM   46   O  O   . ASN A 1 8   ? 44.21002  -11.94991 -24.25990 1.000 48.28263 ? 6   ASN A O   1 
ATOM   47   C  CB  . ASN A 1 8   ? 42.08611  -11.18257 -22.60942 1.000 47.20156 ? 6   ASN A CB  1 
ATOM   48   C  CG  . ASN A 1 8   ? 41.44664  -11.16046 -23.98819 1.000 46.39386 ? 6   ASN A CG  1 
ATOM   49   O  OD1 . ASN A 1 8   ? 41.55888  -10.17738 -24.72539 1.000 44.14575 ? 6   ASN A OD1 1 
ATOM   50   N  ND2 . ASN A 1 8   ? 40.77461  -12.25529 -24.34592 1.000 46.39590 ? 6   ASN A ND2 1 
ATOM   51   N  N   . PRO A 1 9   ? 45.74388  -10.65968 -23.25460 1.000 54.59207 ? 7   PRO A N   1 
ATOM   52   C  CA  . PRO A 1 9   ? 46.76940  -11.01654 -24.23916 1.000 55.38261 ? 7   PRO A CA  1 
ATOM   53   C  C   . PRO A 1 9   ? 47.27054  -12.43993 -24.11100 1.000 58.64415 ? 7   PRO A C   1 
ATOM   54   O  O   . PRO A 1 9   ? 48.03608  -12.88022 -24.97814 1.000 61.39353 ? 7   PRO A O   1 
ATOM   55   C  CB  . PRO A 1 9   ? 47.89151  -10.00280 -23.96538 1.000 53.75089 ? 7   PRO A CB  1 
ATOM   56   C  CG  . PRO A 1 9   ? 47.69266  -9.55859  -22.53964 1.000 53.37230 ? 7   PRO A CG  1 
ATOM   57   C  CD  . PRO A 1 9   ? 46.30614  -9.97272  -22.07923 1.000 54.36360 ? 7   PRO A CD  1 
ATOM   58   N  N   . ASP A 1 10  ? 46.86731  -13.17216 -23.07360 1.000 60.20652 ? 8   ASP A N   1 
ATOM   59   C  CA  . ASP A 1 10  ? 47.21918  -14.57825 -22.92664 1.000 60.28211 ? 8   ASP A CA  1 
ATOM   60   C  C   . ASP A 1 10  ? 46.08975  -15.50572 -23.36035 1.000 63.79639 ? 8   ASP A C   1 
ATOM   61   O  O   . ASP A 1 10  ? 46.16618  -16.71696 -23.12332 1.000 65.14948 ? 8   ASP A O   1 
ATOM   62   C  CB  . ASP A 1 10  ? 47.62846  -14.87073 -21.48112 1.000 64.51235 ? 8   ASP A CB  1 
ATOM   63   C  CG  . ASP A 1 10  ? 48.79123  -13.99820 -21.01584 1.000 70.06465 ? 8   ASP A CG  1 
ATOM   64   O  OD1 . ASP A 1 10  ? 49.72728  -13.77633 -21.81918 1.000 67.39570 ? 8   ASP A OD1 1 
ATOM   65   O  OD2 . ASP A 1 10  ? 48.75428  -13.50994 -19.86036 1.000 70.48476 ? 8   ASP A OD2 1 
ATOM   66   N  N   . GLU A 1 11  ? 45.03969  -14.96726 -23.97441 1.000 60.47697 ? 9   GLU A N   1 
ATOM   67   C  CA  . GLU A 1 11  ? 44.02196  -15.80848 -24.58219 1.000 58.18731 ? 9   GLU A CA  1 
ATOM   68   C  C   . GLU A 1 11  ? 44.51411  -16.25885 -25.94898 1.000 60.24931 ? 9   GLU A C   1 
ATOM   69   O  O   . GLU A 1 11  ? 44.83849  -15.41015 -26.78616 1.000 61.20488 ? 9   GLU A O   1 
ATOM   70   C  CB  . GLU A 1 11  ? 42.69908  -15.06660 -24.72796 1.000 58.57045 ? 9   GLU A CB  1 
ATOM   71   C  CG  . GLU A 1 11  ? 41.83283  -15.61134 -25.86702 1.000 54.35246 ? 9   GLU A CG  1 
ATOM   72   C  CD  . GLU A 1 11  ? 41.20931  -16.95056 -25.52432 1.000 56.88744 ? 9   GLU A CD  1 
ATOM   73   O  OE1 . GLU A 1 11  ? 40.87021  -17.16670 -24.33847 1.000 56.28493 ? 9   GLU A OE1 1 
ATOM   74   O  OE2 . GLU A 1 11  ? 41.08574  -17.80024 -26.43678 1.000 58.29916 ? 9   GLU A OE2 1 
ATOM   75   N  N   . PRO A 1 12  ? 44.58651  -17.56444 -26.21704 1.000 60.13241 ? 10  PRO A N   1 
ATOM   76   C  CA  . PRO A 1 12  ? 45.15582  -18.03175 -27.48961 1.000 60.10419 ? 10  PRO A CA  1 
ATOM   77   C  C   . PRO A 1 12  ? 44.33577  -17.62351 -28.70383 1.000 59.99502 ? 10  PRO A C   1 
ATOM   78   O  O   . PRO A 1 12  ? 44.88060  -17.08646 -29.67446 1.000 62.10018 ? 10  PRO A O   1 
ATOM   79   C  CB  . PRO A 1 12  ? 45.17776  -19.56113 -27.32104 1.000 56.68966 ? 10  PRO A CB  1 
ATOM   80   C  CG  . PRO A 1 12  ? 44.12008  -19.84465 -26.28044 1.000 58.77103 ? 10  PRO A CG  1 
ATOM   81   C  CD  . PRO A 1 12  ? 44.21215  -18.67999 -25.32914 1.000 60.15633 ? 10  PRO A CD  1 
ATOM   82   N  N   . ASN A 1 13  ? 43.02691  -17.87428 -28.65481 1.000 60.43582 ? 11  ASN A N   1 
ATOM   83   C  CA  . ASN A 1 13  ? 42.16120  -17.64339 -29.80393 1.000 52.15212 ? 11  ASN A CA  1 
ATOM   84   C  C   . ASN A 1 13  ? 42.01037  -16.14767 -30.04010 1.000 55.23164 ? 11  ASN A C   1 
ATOM   85   O  O   . ASN A 1 13  ? 41.42331  -15.43208 -29.21779 1.000 54.00339 ? 11  ASN A O   1 
ATOM   86   C  CB  . ASN A 1 13  ? 40.80388  -18.30641 -29.57960 1.000 52.57148 ? 11  ASN A CB  1 
ATOM   87   C  CG  . ASN A 1 13  ? 39.92244  -18.26476 -30.81250 1.000 50.50094 ? 11  ASN A CG  1 
ATOM   88   O  OD1 . ASN A 1 13  ? 40.27361  -17.65853 -31.82457 1.000 51.32495 ? 11  ASN A OD1 1 
ATOM   89   N  ND2 . ASN A 1 13  ? 38.76552  -18.90326 -30.73069 1.000 49.32757 ? 11  ASN A ND2 1 
ATOM   90   N  N   . ALA A 1 14  ? 42.53356  -15.68557 -31.17784 1.000 51.41806 ? 12  ALA A N   1 
ATOM   91   C  CA  . ALA A 1 14  ? 42.52820  -14.26451 -31.49795 1.000 52.78916 ? 12  ALA A CA  1 
ATOM   92   C  C   . ALA A 1 14  ? 41.11443  -13.69895 -31.58458 1.000 47.97163 ? 12  ALA A C   1 
ATOM   93   O  O   . ALA A 1 14  ? 40.89713  -12.52593 -31.25891 1.000 48.73048 ? 12  ALA A O   1 
ATOM   94   C  CB  . ALA A 1 14  ? 43.27775  -14.03470 -32.81352 1.000 51.45495 ? 12  ALA A CB  1 
ATOM   95   N  N   . LEU A 1 15  ? 40.14511  -14.50463 -32.02344 1.000 45.21225 ? 13  LEU A N   1 
ATOM   96   C  CA  . LEU A 1 15  ? 38.77634  -14.02000 -32.13655 1.000 46.86105 ? 13  LEU A CA  1 
ATOM   97   C  C   . LEU A 1 15  ? 38.15838  -13.73035 -30.77740 1.000 44.19412 ? 13  LEU A C   1 
ATOM   98   O  O   . LEU A 1 15  ? 37.16592  -12.99797 -30.70490 1.000 47.28592 ? 13  LEU A O   1 
ATOM   99   C  CB  . LEU A 1 15  ? 37.91458  -15.03085 -32.89183 1.000 47.96698 ? 13  LEU A CB  1 
ATOM   100  C  CG  . LEU A 1 15  ? 38.53596  -15.69582 -34.12038 1.000 50.48819 ? 13  LEU A CG  1 
ATOM   101  C  CD1 . LEU A 1 15  ? 37.74241  -16.93594 -34.52946 1.000 52.26308 ? 13  LEU A CD1 1 
ATOM   102  C  CD2 . LEU A 1 15  ? 38.57546  -14.67809 -35.24053 1.000 51.37011 ? 13  LEU A CD2 1 
ATOM   103  N  N   . LEU A 1 16  ? 38.72308  -14.28107 -29.71031 1.000 44.13640 ? 14  LEU A N   1 
ATOM   104  C  CA  . LEU A 1 16  ? 38.29638  -14.01687 -28.34155 1.000 42.71181 ? 14  LEU A CA  1 
ATOM   105  C  C   . LEU A 1 16  ? 39.08346  -12.87800 -27.70846 1.000 44.12951 ? 14  LEU A C   1 
ATOM   106  O  O   . LEU A 1 16  ? 38.86245  -12.55684 -26.53424 1.000 43.74510 ? 14  LEU A O   1 
ATOM   107  C  CB  . LEU A 1 16  ? 38.43602  -15.29246 -27.49311 1.000 44.34475 ? 14  LEU A CB  1 
ATOM   108  C  CG  . LEU A 1 16  ? 37.16463  -16.13546 -27.37427 1.000 47.15019 ? 14  LEU A CG  1 
ATOM   109  C  CD1 . LEU A 1 16  ? 36.46566  -16.22168 -28.71915 1.000 41.28556 ? 14  LEU A CD1 1 
ATOM   110  C  CD2 . LEU A 1 16  ? 37.50935  -17.53181 -26.86435 1.000 45.46055 ? 14  LEU A CD2 1 
ATOM   111  N  N   . SER A 1 17  ? 39.99348  -12.26796 -28.45933 1.000 42.43597 ? 15  SER A N   1 
ATOM   112  C  CA  . SER A 1 17  ? 40.80579  -11.18306 -27.94101 1.000 42.61833 ? 15  SER A CA  1 
ATOM   113  C  C   . SER A 1 17  ? 39.99056  -9.90057  -27.92308 1.000 40.89225 ? 15  SER A C   1 
ATOM   114  O  O   . SER A 1 17  ? 39.31247  -9.57113  -28.89803 1.000 41.27931 ? 15  SER A O   1 
ATOM   115  C  CB  . SER A 1 17  ? 42.04796  -10.99215 -28.80932 1.000 42.03821 ? 15  SER A CB  1 
ATOM   116  O  OG  . SER A 1 17  ? 42.83497  -9.93368  -28.33037 1.000 42.83055 ? 15  SER A OG  1 
ATOM   117  N  N   . TYR A 1 18  ? 40.05958  -9.17456  -26.81173 1.000 42.22500 ? 16  TYR A N   1 
ATOM   118  C  CA  . TYR A 1 18  ? 39.46384  -7.84150  -26.73745 1.000 41.18172 ? 16  TYR A CA  1 
ATOM   119  C  C   . TYR A 1 18  ? 40.52325  -6.81724  -27.12987 1.000 39.69489 ? 16  TYR A C   1 
ATOM   120  O  O   . TYR A 1 18  ? 41.31622  -6.36133  -26.30497 1.000 42.39121 ? 16  TYR A O   1 
ATOM   121  C  CB  . TYR A 1 18  ? 38.90695  -7.57647  -25.34451 1.000 38.75179 ? 16  TYR A CB  1 
ATOM   122  C  CG  . TYR A 1 18  ? 38.08212  -6.32229  -25.28935 1.000 39.96545 ? 16  TYR A CG  1 
ATOM   123  C  CD1 . TYR A 1 18  ? 36.71441  -6.35412  -25.53575 1.000 38.18891 ? 16  TYR A CD1 1 
ATOM   124  C  CD2 . TYR A 1 18  ? 38.67654  -5.09689  -25.01527 1.000 39.31225 ? 16  TYR A CD2 1 
ATOM   125  C  CE1 . TYR A 1 18  ? 35.95562  -5.19775  -25.47871 1.000 42.88264 ? 16  TYR A CE1 1 
ATOM   126  C  CE2 . TYR A 1 18  ? 37.93339  -3.93978  -24.96875 1.000 43.34269 ? 16  TYR A CE2 1 
ATOM   127  C  CZ  . TYR A 1 18  ? 36.57210  -3.99841  -25.20049 1.000 43.31753 ? 16  TYR A CZ  1 
ATOM   128  O  OH  . TYR A 1 18  ? 35.84080  -2.84402  -25.15967 1.000 46.79896 ? 16  TYR A OH  1 
ATOM   129  N  N   . ASP A 1 19  ? 40.52925  -6.43787  -28.40716 1.000 38.59050 ? 17  ASP A N   1 
ATOM   130  C  CA  . ASP A 1 19  ? 41.50909  -5.49207  -28.91591 1.000 38.49229 ? 17  ASP A CA  1 
ATOM   131  C  C   . ASP A 1 19  ? 41.06800  -4.05151  -28.67162 1.000 42.29633 ? 17  ASP A C   1 
ATOM   132  O  O   . ASP A 1 19  ? 39.89319  -3.70329  -28.85426 1.000 38.22761 ? 17  ASP A O   1 
ATOM   133  C  CB  . ASP A 1 19  ? 41.73065  -5.73431  -30.40812 1.000 40.84753 ? 17  ASP A CB  1 
ATOM   134  C  CG  . ASP A 1 19  ? 42.26997  -7.13765  -30.68550 1.000 45.79029 ? 17  ASP A CG  1 
ATOM   135  O  OD1 . ASP A 1 19  ? 42.86058  -7.73071  -29.75663 1.000 41.70166 ? 17  ASP A OD1 1 
ATOM   136  O  OD2 . ASP A 1 19  ? 42.08368  -7.64636  -31.81150 1.000 47.36565 ? 17  ASP A OD2 1 
ATOM   137  N  N   . PHE A 1 20  ? 42.01928  -3.21275  -28.26442 1.000 42.57571 ? 18  PHE A N   1 
ATOM   138  C  CA  . PHE A 1 20  ? 41.74147  -1.81028  -27.94561 1.000 39.15120 ? 18  PHE A CA  1 
ATOM   139  C  C   . PHE A 1 20  ? 43.04113  -1.03132  -28.05623 1.000 44.94290 ? 18  PHE A C   1 
ATOM   140  O  O   . PHE A 1 20  ? 44.05288  -1.55321  -28.53769 1.000 44.31501 ? 18  PHE A O   1 
ATOM   141  C  CB  . PHE A 1 20  ? 41.14519  -1.65093  -26.54499 1.000 40.83753 ? 18  PHE A CB  1 
ATOM   142  C  CG  . PHE A 1 20  ? 42.14931  -1.81042  -25.43387 1.000 42.37605 ? 18  PHE A CG  1 
ATOM   143  C  CD1 . PHE A 1 20  ? 42.97877  -2.92562  -25.37353 1.000 46.49058 ? 18  PHE A CD1 1 
ATOM   144  C  CD2 . PHE A 1 20  ? 42.26296  -0.84168  -24.44621 1.000 41.74517 ? 18  PHE A CD2 1 
ATOM   145  C  CE1 . PHE A 1 20  ? 43.90995  -3.07669  -24.35013 1.000 47.32857 ? 18  PHE A CE1 1 
ATOM   146  C  CE2 . PHE A 1 20  ? 43.18295  -0.98166  -23.41977 1.000 43.11207 ? 18  PHE A CE2 1 
ATOM   147  C  CZ  . PHE A 1 20  ? 44.00987  -2.10926  -23.36925 1.000 49.93390 ? 18  PHE A CZ  1 
ATOM   148  N  N   . ASP A 1 21  ? 43.01595  0.21689   -27.57627 1.000 40.35024 ? 19  ASP A N   1 
ATOM   149  C  CA  . ASP A 1 21  ? 44.17025  1.10822   -27.58784 1.000 40.10758 ? 19  ASP A CA  1 
ATOM   150  C  C   . ASP A 1 21  ? 44.77067  1.19171   -28.98881 1.000 42.06027 ? 19  ASP A C   1 
ATOM   151  O  O   . ASP A 1 21  ? 45.95325  0.92010   -29.20906 1.000 44.21487 ? 19  ASP A O   1 
ATOM   152  C  CB  . ASP A 1 21  ? 45.23433  0.66733   -26.57916 1.000 41.62398 ? 19  ASP A CB  1 
ATOM   153  C  CG  . ASP A 1 21  ? 46.35388  1.69608   -26.43700 1.000 46.68120 ? 19  ASP A CG  1 
ATOM   154  O  OD1 . ASP A 1 21  ? 46.22981  2.78609   -27.03858 1.000 43.29554 ? 19  ASP A OD1 1 
ATOM   155  O  OD2 . ASP A 1 21  ? 47.35737  1.42022   -25.74994 1.000 47.38466 ? 19  ASP A OD2 1 
ATOM   156  N  N   . ARG A 1 22  ? 43.92936  1.56744   -29.94383 1.000 38.99767 ? 20  ARG A N   1 
ATOM   157  C  CA  . ARG A 1 22  ? 44.35608  1.65763   -31.32949 1.000 44.24339 ? 20  ARG A CA  1 
ATOM   158  C  C   . ARG A 1 22  ? 44.65174  3.08740   -31.74005 1.000 42.16289 ? 20  ARG A C   1 
ATOM   159  O  O   . ARG A 1 22  ? 44.95673  3.33612   -32.90719 1.000 41.46051 ? 20  ARG A O   1 
ATOM   160  C  CB  . ARG A 1 22  ? 43.29912  1.03184   -32.24762 1.000 45.99716 ? 20  ARG A CB  1 
ATOM   161  C  CG  . ARG A 1 22  ? 43.06581  -0.44521  -31.95913 1.000 47.59296 ? 20  ARG A CG  1 
ATOM   162  C  CD  . ARG A 1 22  ? 41.95985  -1.09087  -32.80855 1.000 50.44905 ? 20  ARG A CD  1 
ATOM   163  N  NE  . ARG A 1 22  ? 41.92555  -0.63510  -34.19401 1.000 49.34448 ? 20  ARG A NE  1 
ATOM   164  C  CZ  . ARG A 1 22  ? 41.10323  0.29379   -34.66646 1.000 52.23151 ? 20  ARG A CZ  1 
ATOM   165  N  NH1 . ARG A 1 22  ? 40.31595  0.99630   -33.86492 1.000 47.57483 ? 20  ARG A NH1 1 
ATOM   166  N  NH2 . ARG A 1 22  ? 41.09853  0.55261   -35.97326 1.000 55.55894 ? 20  ARG A NH2 1 
ATOM   167  N  N   . GLY A 1 23  ? 44.58088  4.02980   -30.80299 1.000 41.12498 ? 21  GLY A N   1 
ATOM   168  C  CA  . GLY A 1 23  ? 44.94446  5.40514   -31.09000 1.000 41.54546 ? 21  GLY A CA  1 
ATOM   169  C  C   . GLY A 1 23  ? 43.98937  6.14998   -31.99162 1.000 40.23125 ? 21  GLY A C   1 
ATOM   170  O  O   . GLY A 1 23  ? 44.36395  7.17819   -32.54960 1.000 44.80408 ? 21  GLY A O   1 
ATOM   171  N  N   . SER A 1 24  ? 42.76829  5.65326   -32.16922 1.000 41.19217 ? 22  SER A N   1 
ATOM   172  C  CA  . SER A 1 24  ? 41.80334  6.34744   -33.00959 1.000 36.18694 ? 22  SER A CA  1 
ATOM   173  C  C   . SER A 1 24  ? 41.36530  7.62855   -32.33167 1.000 36.38206 ? 22  SER A C   1 
ATOM   174  O  O   . SER A 1 24  ? 41.47570  7.78089   -31.11167 1.000 37.42679 ? 22  SER A O   1 
ATOM   175  C  CB  . SER A 1 24  ? 40.56834  5.47112   -33.27770 1.000 42.12604 ? 22  SER A CB  1 
ATOM   176  O  OG  . SER A 1 24  ? 39.81903  5.23879   -32.07995 1.000 36.55274 ? 22  SER A OG  1 
ATOM   177  N  N   . ASN A 1 25  ? 40.83781  8.55124   -33.13766 1.000 33.94884 ? 23  ASN A N   1 
ATOM   178  C  CA  . ASN A 1 25  ? 40.34771  9.81281   -32.58191 1.000 37.82521 ? 23  ASN A CA  1 
ATOM   179  C  C   . ASN A 1 25  ? 39.15262  9.59745   -31.66064 1.000 37.34431 ? 23  ASN A C   1 
ATOM   180  O  O   . ASN A 1 25  ? 38.99971  10.31119  -30.66058 1.000 37.36046 ? 23  ASN A O   1 
ATOM   181  C  CB  . ASN A 1 25  ? 39.99540  10.78867  -33.70761 1.000 36.43926 ? 23  ASN A CB  1 
ATOM   182  C  CG  . ASN A 1 25  ? 41.21984  11.47740  -34.27191 1.000 40.60994 ? 23  ASN A CG  1 
ATOM   183  O  OD1 . ASN A 1 25  ? 42.12061  11.82981  -33.51942 1.000 42.07072 ? 23  ASN A OD1 1 
ATOM   184  N  ND2 . ASN A 1 25  ? 41.24806  11.69910  -35.59548 1.000 37.04115 ? 23  ASN A ND2 1 
ATOM   185  N  N   . TYR A 1 26  ? 38.28741  8.62976   -31.98299 1.000 34.68250 ? 24  TYR A N   1 
ATOM   186  C  CA  . TYR A 1 26  ? 37.21068  8.27876   -31.06886 1.000 35.89951 ? 24  TYR A CA  1 
ATOM   187  C  C   . TYR A 1 26  ? 37.77044  7.95205   -29.68692 1.000 35.16196 ? 24  TYR A C   1 
ATOM   188  O  O   . TYR A 1 26  ? 37.33577  8.51337   -28.67227 1.000 34.04240 ? 24  TYR A O   1 
ATOM   189  C  CB  . TYR A 1 26  ? 36.42385  7.10139   -31.65445 1.000 36.32911 ? 24  TYR A CB  1 
ATOM   190  C  CG  . TYR A 1 26  ? 35.37931  6.50700   -30.73834 1.000 36.09034 ? 24  TYR A CG  1 
ATOM   191  C  CD1 . TYR A 1 26  ? 34.08028  7.00366   -30.72749 1.000 31.45685 ? 24  TYR A CD1 1 
ATOM   192  C  CD2 . TYR A 1 26  ? 35.68432  5.43295   -29.91049 1.000 32.85460 ? 24  TYR A CD2 1 
ATOM   193  C  CE1 . TYR A 1 26  ? 33.10869  6.46359   -29.89973 1.000 31.29762 ? 24  TYR A CE1 1 
ATOM   194  C  CE2 . TYR A 1 26  ? 34.70640  4.86504   -29.07206 1.000 30.93751 ? 24  TYR A CE2 1 
ATOM   195  C  CZ  . TYR A 1 26  ? 33.42188  5.39594   -29.07425 1.000 33.04591 ? 24  TYR A CZ  1 
ATOM   196  O  OH  . TYR A 1 26  ? 32.44779  4.85922   -28.24177 1.000 33.98881 ? 24  TYR A OH  1 
ATOM   197  N  N   . GLU A 1 27  ? 38.76732  7.05585   -29.63888 1.000 36.41873 ? 25  GLU A N   1 
ATOM   198  C  CA  . GLU A 1 27  ? 39.40386  6.69036   -28.37521 1.000 35.68912 ? 25  GLU A CA  1 
ATOM   199  C  C   . GLU A 1 27  ? 40.12839  7.87853   -27.74151 1.000 37.40354 ? 25  GLU A C   1 
ATOM   200  O  O   . GLU A 1 27  ? 40.10342  8.04622   -26.51371 1.000 37.63490 ? 25  GLU A O   1 
ATOM   201  C  CB  . GLU A 1 27  ? 40.38441  5.54228   -28.61265 1.000 36.53575 ? 25  GLU A CB  1 
ATOM   202  C  CG  . GLU A 1 27  ? 39.75472  4.22303   -29.01338 1.000 36.13486 ? 25  GLU A CG  1 
ATOM   203  C  CD  . GLU A 1 27  ? 40.77811  3.32343   -29.68108 1.000 38.02594 ? 25  GLU A CD  1 
ATOM   204  O  OE1 . GLU A 1 27  ? 41.22065  3.68955   -30.79467 1.000 38.52698 ? 25  GLU A OE1 1 
ATOM   205  O  OE2 . GLU A 1 27  ? 41.16639  2.30643   -29.05739 1.000 35.72103 ? 25  GLU A OE2 1 
ATOM   206  N  N   . ASN A 1 28  ? 40.78702  8.70997   -28.55663 1.000 38.79426 ? 26  ASN A N   1 
ATOM   207  C  CA  . ASN A 1 28  ? 41.54010  9.84109   -28.01231 1.000 35.33770 ? 26  ASN A CA  1 
ATOM   208  C  C   . ASN A 1 28  ? 40.60898  10.84295  -27.34598 1.000 39.13472 ? 26  ASN A C   1 
ATOM   209  O  O   . ASN A 1 28  ? 40.83712  11.26855  -26.20631 1.000 40.10227 ? 26  ASN A O   1 
ATOM   210  C  CB  . ASN A 1 28  ? 42.33843  10.54083  -29.11685 1.000 39.91217 ? 26  ASN A CB  1 
ATOM   211  C  CG  . ASN A 1 28  ? 43.51422  9.71630   -29.61630 1.000 42.58436 ? 26  ASN A CG  1 
ATOM   212  O  OD1 . ASN A 1 28  ? 43.99981  8.81510   -28.93554 1.000 46.51516 ? 26  ASN A OD1 1 
ATOM   213  N  ND2 . ASN A 1 28  ? 43.96512  10.01874  -30.82330 1.000 43.58119 ? 26  ASN A ND2 1 
ATOM   214  N  N   . VAL A 1 29  ? 39.55864  11.24547  -28.05884 1.000 36.59230 ? 27  VAL A N   1 
ATOM   215  C  CA  . VAL A 1 29  ? 38.63652  12.24496  -27.53270 1.000 38.12858 ? 27  VAL A CA  1 
ATOM   216  C  C   . VAL A 1 29  ? 38.04204  11.78794  -26.19883 1.000 37.56292 ? 27  VAL A C   1 
ATOM   217  O  O   . VAL A 1 29  ? 37.83253  12.60487  -25.29216 1.000 38.60828 ? 27  VAL A O   1 
ATOM   218  C  CB  . VAL A 1 29  ? 37.54886  12.54560  -28.57983 1.000 39.43690 ? 27  VAL A CB  1 
ATOM   219  C  CG1 . VAL A 1 29  ? 36.37914  13.33460  -27.96539 1.000 34.45779 ? 27  VAL A CG1 1 
ATOM   220  C  CG2 . VAL A 1 29  ? 38.16026  13.27307  -29.78844 1.000 39.48144 ? 27  VAL A CG2 1 
ATOM   221  N  N   . LEU A 1 30  ? 37.78779  10.48280  -26.04105 1.000 36.88234 ? 28  LEU A N   1 
ATOM   222  C  CA  . LEU A 1 30  ? 37.10851  9.97361   -24.84747 1.000 36.50818 ? 28  LEU A CA  1 
ATOM   223  C  C   . LEU A 1 30  ? 38.04680  9.58247   -23.71181 1.000 38.87637 ? 28  LEU A C   1 
ATOM   224  O  O   . LEU A 1 30  ? 37.55914  9.19820   -22.64568 1.000 37.67579 ? 28  LEU A O   1 
ATOM   225  C  CB  . LEU A 1 30  ? 36.23921  8.74829   -25.19019 1.000 36.52968 ? 28  LEU A CB  1 
ATOM   226  C  CG  . LEU A 1 30  ? 35.10238  8.99005   -26.18465 1.000 35.27332 ? 28  LEU A CG  1 
ATOM   227  C  CD1 . LEU A 1 30  ? 34.46726  7.66448   -26.58264 1.000 30.18987 ? 28  LEU A CD1 1 
ATOM   228  C  CD2 . LEU A 1 30  ? 34.04356  9.96293   -25.61695 1.000 35.26260 ? 28  LEU A CD2 1 
ATOM   229  N  N   . HIS A 1 31  ? 39.36895  9.64453   -23.89676 1.000 39.42895 ? 29  HIS A N   1 
ATOM   230  C  CA  . HIS A 1 31  ? 40.28744  9.05845   -22.91522 1.000 40.16812 ? 29  HIS A CA  1 
ATOM   231  C  C   . HIS A 1 31  ? 39.87459  7.62241   -22.59653 1.000 38.59751 ? 29  HIS A C   1 
ATOM   232  O  O   . HIS A 1 31  ? 39.87964  7.18669   -21.44121 1.000 41.47095 ? 29  HIS A O   1 
ATOM   233  C  CB  . HIS A 1 31  ? 40.35338  9.87881   -21.61817 1.000 39.90526 ? 29  HIS A CB  1 
ATOM   234  C  CG  . HIS A 1 31  ? 40.76647  11.31357  -21.78991 1.000 44.02386 ? 29  HIS A CG  1 
ATOM   235  N  ND1 . HIS A 1 31  ? 40.41267  12.08433  -22.87794 1.000 42.82083 ? 29  HIS A ND1 1 
ATOM   236  C  CD2 . HIS A 1 31  ? 41.47571  12.12749  -20.97195 1.000 41.57951 ? 29  HIS A CD2 1 
ATOM   237  C  CE1 . HIS A 1 31  ? 40.90872  13.29816  -22.73442 1.000 42.63927 ? 29  HIS A CE1 1 
ATOM   238  N  NE2 . HIS A 1 31  ? 41.54764  13.35362  -21.58043 1.000 41.87889 ? 29  HIS A NE2 1 
ATOM   239  N  N   . LEU A 1 32  ? 39.46374  6.88639   -23.62771 1.000 36.33454 ? 30  LEU A N   1 
ATOM   240  C  CA  . LEU A 1 32  ? 38.85127  5.58592   -23.39422 1.000 37.26623 ? 30  LEU A CA  1 
ATOM   241  C  C   . LEU A 1 32  ? 39.87907  4.55699   -22.94182 1.000 41.81427 ? 30  LEU A C   1 
ATOM   242  O  O   . LEU A 1 32  ? 39.56172  3.65984   -22.14426 1.000 36.93521 ? 30  LEU A O   1 
ATOM   243  C  CB  . LEU A 1 32  ? 38.16320  5.10279   -24.66350 1.000 39.29216 ? 30  LEU A CB  1 
ATOM   244  C  CG  . LEU A 1 32  ? 37.55923  3.69909   -24.65578 1.000 37.16228 ? 30  LEU A CG  1 
ATOM   245  C  CD1 . LEU A 1 32  ? 36.67107  3.47496   -23.41742 1.000 34.00633 ? 30  LEU A CD1 1 
ATOM   246  C  CD2 . LEU A 1 32  ? 36.79570  3.49841   -25.93164 1.000 32.78380 ? 30  LEU A CD2 1 
ATOM   247  N  N   . THR A 1 33  ? 41.11464  4.68723   -23.42769 1.000 40.56544 ? 31  THR A N   1 
ATOM   248  C  CA  . THR A 1 33  ? 42.13931  3.71016   -23.09270 1.000 39.36946 ? 31  THR A CA  1 
ATOM   249  C  C   . THR A 1 33  ? 42.49816  3.84057   -21.62248 1.000 40.19174 ? 31  THR A C   1 
ATOM   250  O  O   . THR A 1 33  ? 42.66437  2.84298   -20.91698 1.000 44.16147 ? 31  THR A O   1 
ATOM   251  C  CB  . THR A 1 33  ? 43.36519  3.94975   -23.96580 1.000 38.89962 ? 31  THR A CB  1 
ATOM   252  O  OG1 . THR A 1 33  ? 43.09401  3.47810   -25.28507 1.000 37.86069 ? 31  THR A OG1 1 
ATOM   253  C  CG2 . THR A 1 33  ? 44.53629  3.13764   -23.43776 1.000 43.13041 ? 31  THR A CG2 1 
ATOM   254  N  N   . ASP A 1 34  ? 42.57324  5.08344   -21.14165 1.000 40.12054 ? 32  ASP A N   1 
ATOM   255  C  CA  . ASP A 1 34  ? 42.81836  5.34041   -19.72938 1.000 43.02279 ? 32  ASP A CA  1 
ATOM   256  C  C   . ASP A 1 34  ? 41.70816  4.74908   -18.86607 1.000 45.25072 ? 32  ASP A C   1 
ATOM   257  O  O   . ASP A 1 34  ? 41.97892  4.06719   -17.86888 1.000 44.43072 ? 32  ASP A O   1 
ATOM   258  C  CB  . ASP A 1 34  ? 42.93976  6.84812   -19.52118 1.000 47.83467 ? 32  ASP A CB  1 
ATOM   259  C  CG  . ASP A 1 34  ? 44.34886  7.34316   -19.73231 1.000 50.30241 ? 32  ASP A CG  1 
ATOM   260  O  OD1 . ASP A 1 34  ? 45.19135  6.55624   -20.22584 1.000 56.30262 ? 32  ASP A OD1 1 
ATOM   261  O  OD2 . ASP A 1 34  ? 44.60017  8.52970   -19.45845 1.000 56.83778 ? 32  ASP A OD2 1 
ATOM   262  N  N   . ALA A 1 35  ? 40.44899  4.95705   -19.26444 1.000 41.51931 ? 33  ALA A N   1 
ATOM   263  C  CA  . ALA A 1 35  ? 39.33012  4.40757   -18.50257 1.000 43.98635 ? 33  ALA A CA  1 
ATOM   264  C  C   . ALA A 1 35  ? 39.35134  2.87809   -18.47709 1.000 43.13034 ? 33  ALA A C   1 
ATOM   265  O  O   . ALA A 1 35  ? 39.13115  2.26485   -17.42421 1.000 41.19731 ? 33  ALA A O   1 
ATOM   266  C  CB  . ALA A 1 35  ? 38.01170  4.92791   -19.07388 1.000 41.41903 ? 33  ALA A CB  1 
ATOM   267  N  N   . LEU A 1 36  ? 39.61470  2.24049   -19.62391 1.000 40.99167 ? 34  LEU A N   1 
ATOM   268  C  CA  . LEU A 1 36  ? 39.68520  0.78591   -19.66155 1.000 42.73153 ? 34  LEU A CA  1 
ATOM   269  C  C   . LEU A 1 36  ? 40.84386  0.26278   -18.81414 1.000 44.34303 ? 34  LEU A C   1 
ATOM   270  O  O   . LEU A 1 36  ? 40.77025  -0.86133  -18.30730 1.000 43.43116 ? 34  LEU A O   1 
ATOM   271  C  CB  . LEU A 1 36  ? 39.79402  0.31198   -21.11980 1.000 41.98657 ? 34  LEU A CB  1 
ATOM   272  C  CG  . LEU A 1 36  ? 38.51487  0.48321   -21.96167 1.000 36.24948 ? 34  LEU A CG  1 
ATOM   273  C  CD1 . LEU A 1 36  ? 38.77399  0.28794   -23.45660 1.000 36.15452 ? 34  LEU A CD1 1 
ATOM   274  C  CD2 . LEU A 1 36  ? 37.39589  -0.41932  -21.47863 1.000 44.53953 ? 34  LEU A CD2 1 
ATOM   275  N  N   . GLY A 1 37  ? 41.87991  1.08298   -18.59851 1.000 45.50102 ? 35  GLY A N   1 
ATOM   276  C  CA  . GLY A 1 37  ? 42.99034  0.75401   -17.71972 1.000 42.25166 ? 35  GLY A CA  1 
ATOM   277  C  C   . GLY A 1 37  ? 42.63002  0.63411   -16.24863 1.000 43.25849 ? 35  GLY A C   1 
ATOM   278  O  O   . GLY A 1 37  ? 43.44904  0.12482   -15.47548 1.000 41.03549 ? 35  GLY A O   1 
ATOM   279  N  N   . ALA A 1 38  ? 41.43860  1.07861   -15.83950 1.000 38.63521 ? 36  ALA A N   1 
ATOM   280  C  CA  . ALA A 1 38  ? 41.02081  0.85780   -14.45609 1.000 43.88428 ? 36  ALA A CA  1 
ATOM   281  C  C   . ALA A 1 38  ? 40.58300  -0.57869  -14.18090 1.000 42.92514 ? 36  ALA A C   1 
ATOM   282  O  O   . ALA A 1 38  ? 40.51818  -0.97802  -13.01313 1.000 42.30637 ? 36  ALA A O   1 
ATOM   283  C  CB  . ALA A 1 38  ? 39.87261  1.79358   -14.06792 1.000 39.68036 ? 36  ALA A CB  1 
ATOM   284  N  N   . LEU A 1 39  ? 40.23467  -1.34437  -15.20996 1.000 42.09939 ? 37  LEU A N   1 
ATOM   285  C  CA  . LEU A 1 39  ? 39.73258  -2.68926  -14.98105 1.000 44.02280 ? 37  LEU A CA  1 
ATOM   286  C  C   . LEU A 1 39  ? 40.83782  -3.54908  -14.38578 1.000 45.24798 ? 37  LEU A C   1 
ATOM   287  O  O   . LEU A 1 39  ? 41.99911  -3.46302  -14.80022 1.000 45.83542 ? 37  LEU A O   1 
ATOM   288  C  CB  . LEU A 1 39  ? 39.22344  -3.30489  -16.28542 1.000 45.21439 ? 37  LEU A CB  1 
ATOM   289  C  CG  . LEU A 1 39  ? 38.10477  -2.56773  -17.03140 1.000 47.91972 ? 37  LEU A CG  1 
ATOM   290  C  CD1 . LEU A 1 39  ? 37.77329  -3.26787  -18.34850 1.000 46.35763 ? 37  LEU A CD1 1 
ATOM   291  C  CD2 . LEU A 1 39  ? 36.86424  -2.39404  -16.15952 1.000 43.10261 ? 37  LEU A CD2 1 
ATOM   292  N  N   . VAL A 1 40  ? 40.48139  -4.34183  -13.38174 1.000 42.88545 ? 38  VAL A N   1 
ATOM   293  C  CA  . VAL A 1 40  ? 41.47425  -5.24946  -12.78813 1.000 47.82984 ? 38  VAL A CA  1 
ATOM   294  C  C   . VAL A 1 40  ? 42.02121  -6.17108  -13.87082 1.000 46.95179 ? 38  VAL A C   1 
ATOM   295  O  O   . VAL A 1 40  ? 41.23540  -6.77244  -14.63134 1.000 45.41203 ? 38  VAL A O   1 
ATOM   296  C  CB  . VAL A 1 40  ? 40.86008  -6.06301  -11.63368 1.000 48.14233 ? 38  VAL A CB  1 
ATOM   297  C  CG1 . VAL A 1 40  ? 39.60128  -6.79175  -12.09220 1.000 50.19490 ? 38  VAL A CG1 1 
ATOM   298  C  CG2 . VAL A 1 40  ? 41.87161  -7.07993  -11.10634 1.000 48.00935 ? 38  VAL A CG2 1 
ATOM   299  N  N   . PRO A 1 41  ? 43.33827  -6.29760  -14.00696 1.000 49.42404 ? 39  PRO A N   1 
ATOM   300  C  CA  . PRO A 1 41  ? 43.89450  -7.19295  -15.03031 1.000 48.64228 ? 39  PRO A CA  1 
ATOM   301  C  C   . PRO A 1 41  ? 43.37732  -8.62037  -14.90425 1.000 49.52759 ? 39  PRO A C   1 
ATOM   302  O  O   . PRO A 1 41  ? 43.12989  -9.13167  -13.80549 1.000 47.64126 ? 39  PRO A O   1 
ATOM   303  C  CB  . PRO A 1 41  ? 45.40491  -7.10401  -14.78387 1.000 52.03318 ? 39  PRO A CB  1 
ATOM   304  C  CG  . PRO A 1 41  ? 45.58327  -5.69307  -14.22869 1.000 50.53150 ? 39  PRO A CG  1 
ATOM   305  C  CD  . PRO A 1 41  ? 44.37891  -5.48821  -13.34683 1.000 48.19917 ? 39  PRO A CD  1 
ATOM   306  N  N   . GLU A 1 42  ? 43.17646  -9.25061  -16.06332 1.000 47.49106 ? 40  GLU A N   1 
ATOM   307  C  CA  . GLU A 1 42  ? 42.67623  -10.61752 -16.07907 1.000 48.08746 ? 40  GLU A CA  1 
ATOM   308  C  C   . GLU A 1 42  ? 43.61894  -11.55099 -15.33128 1.000 50.07988 ? 40  GLU A C   1 
ATOM   309  O  O   . GLU A 1 42  ? 43.16872  -12.46422 -14.63228 1.000 50.54828 ? 40  GLU A O   1 
ATOM   310  C  CB  . GLU A 1 42  ? 42.46059  -11.07001 -17.52378 1.000 49.82998 ? 40  GLU A CB  1 
ATOM   311  C  CG  . GLU A 1 42  ? 40.98756  -10.99410 -17.93944 1.000 49.53995 ? 40  GLU A CG  1 
ATOM   312  C  CD  . GLU A 1 42  ? 40.70378  -11.63142 -19.28013 1.000 46.59315 ? 40  GLU A CD  1 
ATOM   313  O  OE1 . GLU A 1 42  ? 40.92066  -12.84438 -19.42687 1.000 51.95704 ? 40  GLU A OE1 1 
ATOM   314  O  OE2 . GLU A 1 42  ? 40.21473  -10.93058 -20.17835 1.000 48.48092 ? 40  GLU A OE2 1 
ATOM   315  N  N   . SER A 1 43  ? 44.92766  -11.29466 -15.41413 1.000 50.64543 ? 41  SER A N   1 
ATOM   316  C  CA  . SER A 1 43  ? 45.89893  -12.11293 -14.70147 1.000 49.17209 ? 41  SER A CA  1 
ATOM   317  C  C   . SER A 1 43  ? 45.70421  -12.05812 -13.19603 1.000 53.74308 ? 41  SER A C   1 
ATOM   318  O  O   . SER A 1 43  ? 46.12585  -12.99083 -12.49989 1.000 51.65848 ? 41  SER A O   1 
ATOM   319  C  CB  . SER A 1 43  ? 47.32544  -11.68154 -15.05719 1.000 47.84811 ? 41  SER A CB  1 
ATOM   320  O  OG  . SER A 1 43  ? 47.59152  -10.35352 -14.63284 1.000 59.04118 ? 41  SER A OG  1 
ATOM   321  N  N   . GLU A 1 44  ? 45.04703  -11.01219 -12.67946 1.000 50.42735 ? 42  GLU A N   1 
ATOM   322  C  CA  . GLU A 1 44  ? 44.93748  -10.79834 -11.24129 1.000 52.19864 ? 42  GLU A CA  1 
ATOM   323  C  C   . GLU A 1 44  ? 43.54617  -11.05971 -10.66656 1.000 51.16524 ? 42  GLU A C   1 
ATOM   324  O  O   . GLU A 1 44  ? 43.35875  -10.88252 -9.45960  1.000 53.73102 ? 42  GLU A O   1 
ATOM   325  C  CB  . GLU A 1 44  ? 45.36594  -9.36573  -10.88082 1.000 48.96253 ? 42  GLU A CB  1 
ATOM   326  C  CG  . GLU A 1 44  ? 46.57484  -8.83696  -11.65301 1.000 53.72481 ? 42  GLU A CG  1 
ATOM   327  C  CD  . GLU A 1 44  ? 46.99731  -7.43214  -11.20824 1.000 55.89235 ? 42  GLU A CD  1 
ATOM   328  O  OE1 . GLU A 1 44  ? 48.12794  -7.00377  -11.55006 1.000 61.65793 ? 42  GLU A OE1 1 
ATOM   329  O  OE2 . GLU A 1 44  ? 46.20928  -6.76950  -10.50143 1.000 56.76577 ? 42  GLU A OE2 1 
ATOM   330  N  N   . THR A 1 45  ? 42.56564  -11.46891 -11.47116 1.000 51.00359 ? 43  THR A N   1 
ATOM   331  C  CA  . THR A 1 45  ? 41.23485  -11.70165 -10.91724 1.000 49.61491 ? 43  THR A CA  1 
ATOM   332  C  C   . THR A 1 45  ? 41.23119  -12.97856 -10.09090 1.000 50.51795 ? 43  THR A C   1 
ATOM   333  O  O   . THR A 1 45  ? 41.90103  -13.95460 -10.42788 1.000 50.75044 ? 43  THR A O   1 
ATOM   334  C  CB  . THR A 1 45  ? 40.17177  -11.78503 -12.01997 1.000 50.08333 ? 43  THR A CB  1 
ATOM   335  O  OG1 . THR A 1 45  ? 40.59188  -12.69747 -13.04146 1.000 48.67607 ? 43  THR A OG1 1 
ATOM   336  C  CG2 . THR A 1 45  ? 39.92763  -10.39843 -12.64682 1.000 43.08819 ? 43  THR A CG2 1 
ATOM   337  N  N   . GLU A 1 46  ? 40.48369  -12.95643 -8.98980  1.000 54.50140 ? 44  GLU A N   1 
ATOM   338  C  CA  . GLU A 1 46  ? 40.39262  -14.08169 -8.06959  1.000 53.23579 ? 44  GLU A CA  1 
ATOM   339  C  C   . GLU A 1 46  ? 39.06777  -14.82771 -8.17153  1.000 49.05966 ? 44  GLU A C   1 
ATOM   340  O  O   . GLU A 1 46  ? 38.87166  -15.80390 -7.44735  1.000 51.61820 ? 44  GLU A O   1 
ATOM   341  C  CB  . GLU A 1 46  ? 40.59716  -13.59601 -6.62394  1.000 49.50450 ? 44  GLU A CB  1 
ATOM   342  N  N   . HIS A 1 47  ? 38.14951  -14.37743 -9.03509  1.000 47.96084 ? 45  HIS A N   1 
ATOM   343  C  CA  . HIS A 1 47  ? 36.83878  -14.98996 -9.21984  1.000 45.04343 ? 45  HIS A CA  1 
ATOM   344  C  C   . HIS A 1 47  ? 36.29122  -14.54505 -10.56138 1.000 42.91697 ? 45  HIS A C   1 
ATOM   345  O  O   . HIS A 1 47  ? 36.48194  -13.38303 -10.92247 1.000 39.99887 ? 45  HIS A O   1 
ATOM   346  C  CB  . HIS A 1 47  ? 35.86182  -14.59957 -8.11573  1.000 43.74796 ? 45  HIS A CB  1 
ATOM   347  C  CG  . HIS A 1 47  ? 34.64081  -15.46209 -8.07410  1.000 43.90035 ? 45  HIS A CG  1 
ATOM   348  N  ND1 . HIS A 1 47  ? 33.60330  -15.32298 -8.97228  1.000 43.30635 ? 45  HIS A ND1 1 
ATOM   349  C  CD2 . HIS A 1 47  ? 34.28314  -16.46518 -7.23874  1.000 45.11596 ? 45  HIS A CD2 1 
ATOM   350  C  CE1 . HIS A 1 47  ? 32.66908  -16.21891 -8.70565  1.000 43.25354 ? 45  HIS A CE1 1 
ATOM   351  N  NE2 . HIS A 1 47  ? 33.05640  -16.92332 -7.65709  1.000 46.35620 ? 45  HIS A NE2 1 
ATOM   352  N  N   . PRO A 1 48  ? 35.62284  -15.41642 -11.32385 1.000 43.59671 ? 46  PRO A N   1 
ATOM   353  C  CA  . PRO A 1 48  ? 35.12753  -14.98934 -12.64298 1.000 41.46797 ? 46  PRO A CA  1 
ATOM   354  C  C   . PRO A 1 48  ? 34.00738  -13.95023 -12.57346 1.000 40.32218 ? 46  PRO A C   1 
ATOM   355  O  O   . PRO A 1 48  ? 33.69674  -13.33787 -13.59637 1.000 42.68650 ? 46  PRO A O   1 
ATOM   356  C  CB  . PRO A 1 48  ? 34.62740  -16.29591 -13.27484 1.000 38.35784 ? 46  PRO A CB  1 
ATOM   357  C  CG  . PRO A 1 48  ? 34.35398  -17.20515 -12.13096 1.000 42.05108 ? 46  PRO A CG  1 
ATOM   358  C  CD  . PRO A 1 48  ? 35.23835  -16.80122 -10.99880 1.000 44.53967 ? 46  PRO A CD  1 
ATOM   359  N  N   . ASP A 1 49  ? 33.38324  -13.73906 -11.42557 1.000 39.39609 ? 47  ASP A N   1 
ATOM   360  C  CA  . ASP A 1 49  ? 32.37294  -12.69753 -11.30376 1.000 38.48077 ? 47  ASP A CA  1 
ATOM   361  C  C   . ASP A 1 49  ? 32.93877  -11.38790 -10.77500 1.000 40.07093 ? 47  ASP A C   1 
ATOM   362  O  O   . ASP A 1 49  ? 32.18544  -10.42972 -10.61614 1.000 41.56261 ? 47  ASP A O   1 
ATOM   363  C  CB  . ASP A 1 49  ? 31.22903  -13.17385 -10.40619 1.000 38.63877 ? 47  ASP A CB  1 
ATOM   364  C  CG  . ASP A 1 49  ? 30.36980  -14.23032 -11.08153 1.000 39.13147 ? 47  ASP A CG  1 
ATOM   365  O  OD1 . ASP A 1 49  ? 30.26030  -14.19789 -12.33355 1.000 38.88245 ? 47  ASP A OD1 1 
ATOM   366  O  OD2 . ASP A 1 49  ? 29.84598  -15.10384 -10.36619 1.000 35.89935 ? 47  ASP A OD2 1 
ATOM   367  N  N   . GLN A 1 50  ? 34.24653  -11.30914 -10.54201 1.000 39.43437 ? 48  GLN A N   1 
ATOM   368  C  CA  . GLN A 1 50  ? 34.82629  -10.09038 -9.99133  1.000 39.03595 ? 48  GLN A CA  1 
ATOM   369  C  C   . GLN A 1 50  ? 34.72662  -8.91863  -10.96533 1.000 38.80570 ? 48  GLN A C   1 
ATOM   370  O  O   . GLN A 1 50  ? 34.43949  -7.79146  -10.54734 1.000 41.44014 ? 48  GLN A O   1 
ATOM   371  C  CB  . GLN A 1 50  ? 36.27854  -10.34234 -9.60630  1.000 40.15056 ? 48  GLN A CB  1 
ATOM   372  C  CG  . GLN A 1 50  ? 37.02511  -9.08682  -9.19904  1.000 45.21249 ? 48  GLN A CG  1 
ATOM   373  C  CD  . GLN A 1 50  ? 38.41620  -9.39942  -8.70863  1.000 50.00436 ? 48  GLN A CD  1 
ATOM   374  O  OE1 . GLN A 1 50  ? 38.80811  -10.57237 -8.62445  1.000 53.07106 ? 48  GLN A OE1 1 
ATOM   375  N  NE2 . GLN A 1 50  ? 39.17237  -8.36209  -8.37185  1.000 48.80239 ? 48  GLN A NE2 1 
ATOM   376  N  N   . ARG A 1 51  ? 34.97412  -9.14953  -12.26221 1.000 37.59965 ? 49  ARG A N   1 
ATOM   377  C  CA  . ARG A 1 51  ? 34.86286  -8.05864  -13.23620 1.000 38.12887 ? 49  ARG A CA  1 
ATOM   378  C  C   . ARG A 1 51  ? 33.45558  -7.47034  -13.23701 1.000 36.65674 ? 49  ARG A C   1 
ATOM   379  O  O   . ARG A 1 51  ? 33.28077  -6.25215  -13.14317 1.000 39.37876 ? 49  ARG A O   1 
ATOM   380  C  CB  . ARG A 1 51  ? 35.24560  -8.54354  -14.64191 1.000 38.34562 ? 49  ARG A CB  1 
ATOM   381  C  CG  . ARG A 1 51  ? 36.73895  -8.42217  -14.97345 1.000 37.91640 ? 49  ARG A CG  1 
ATOM   382  C  CD  . ARG A 1 51  ? 37.14716  -6.98343  -15.34259 1.000 40.61090 ? 49  ARG A CD  1 
ATOM   383  N  NE  . ARG A 1 51  ? 38.52061  -6.94245  -15.82446 1.000 40.32861 ? 49  ARG A NE  1 
ATOM   384  C  CZ  . ARG A 1 51  ? 38.87744  -7.21177  -17.07418 1.000 42.41602 ? 49  ARG A CZ  1 
ATOM   385  N  NH1 . ARG A 1 51  ? 37.97814  -7.44018  -18.01546 1.000 42.02365 ? 49  ARG A NH1 1 
ATOM   386  N  NH2 . ARG A 1 51  ? 40.16936  -7.27108  -17.38350 1.000 43.27241 ? 49  ARG A NH2 1 
ATOM   387  N  N   . PHE A 1 52  ? 32.44014  -8.32925  -13.33928 1.000 38.38928 ? 50  PHE A N   1 
ATOM   388  C  CA  . PHE A 1 52  ? 31.05602  -7.87926  -13.25524 1.000 39.84505 ? 50  PHE A CA  1 
ATOM   389  C  C   . PHE A 1 52  ? 30.82831  -7.00552  -12.02680 1.000 39.28301 ? 50  PHE A C   1 
ATOM   390  O  O   . PHE A 1 52  ? 30.23132  -5.92739  -12.11694 1.000 38.13545 ? 50  PHE A O   1 
ATOM   391  C  CB  . PHE A 1 52  ? 30.14437  -9.09359  -13.21539 1.000 35.09505 ? 50  PHE A CB  1 
ATOM   392  C  CG  . PHE A 1 52  ? 28.67443  -8.76424  -13.20304 1.000 35.71610 ? 50  PHE A CG  1 
ATOM   393  C  CD1 . PHE A 1 52  ? 28.12300  -7.96578  -14.18681 1.000 34.31580 ? 50  PHE A CD1 1 
ATOM   394  C  CD2 . PHE A 1 52  ? 27.84010  -9.31594  -12.24433 1.000 35.29443 ? 50  PHE A CD2 1 
ATOM   395  C  CE1 . PHE A 1 52  ? 26.77153  -7.68580  -14.19778 1.000 35.98195 ? 50  PHE A CE1 1 
ATOM   396  C  CE2 . PHE A 1 52  ? 26.46811  -9.04621  -12.24351 1.000 38.38211 ? 50  PHE A CE2 1 
ATOM   397  C  CZ  . PHE A 1 52  ? 25.94155  -8.23061  -13.22275 1.000 35.83917 ? 50  PHE A CZ  1 
ATOM   398  N  N   . PHE A 1 53  ? 31.27367  -7.48385  -10.86268 1.000 36.89252 ? 51  PHE A N   1 
ATOM   399  C  CA  . PHE A 1 53  ? 31.21864  -6.69332  -9.63842  1.000 39.68445 ? 51  PHE A CA  1 
ATOM   400  C  C   . PHE A 1 53  ? 31.79192  -5.29892  -9.87103  1.000 41.12941 ? 51  PHE A C   1 
ATOM   401  O  O   . PHE A 1 53  ? 31.10965  -4.28270  -9.66223  1.000 40.13280 ? 51  PHE A O   1 
ATOM   402  C  CB  . PHE A 1 53  ? 31.98112  -7.44940  -8.54162  1.000 39.98203 ? 51  PHE A CB  1 
ATOM   403  C  CG  . PHE A 1 53  ? 31.89893  -6.83698  -7.15993  1.000 39.00008 ? 51  PHE A CG  1 
ATOM   404  C  CD1 . PHE A 1 53  ? 32.85913  -5.93738  -6.72974  1.000 38.56862 ? 51  PHE A CD1 1 
ATOM   405  C  CD2 . PHE A 1 53  ? 30.92063  -7.23149  -6.27122  1.000 40.91650 ? 51  PHE A CD2 1 
ATOM   406  C  CE1 . PHE A 1 53  ? 32.81289  -5.40466  -5.46152  1.000 42.36758 ? 51  PHE A CE1 1 
ATOM   407  C  CE2 . PHE A 1 53  ? 30.86228  -6.69153  -4.99701  1.000 41.47304 ? 51  PHE A CE2 1 
ATOM   408  C  CZ  . PHE A 1 53  ? 31.80634  -5.77867  -4.59581  1.000 43.09569 ? 51  PHE A CZ  1 
ATOM   409  N  N   . GLN A 1 54  ? 33.03023  -5.23857  -10.37291 1.000 38.48774 ? 52  GLN A N   1 
ATOM   410  C  CA  . GLN A 1 54  ? 33.72032  -3.96424  -10.50618 1.000 37.82205 ? 52  GLN A CA  1 
ATOM   411  C  C   . GLN A 1 54  ? 33.00601  -3.04133  -11.48022 1.000 41.53388 ? 52  GLN A C   1 
ATOM   412  O  O   . GLN A 1 54  ? 32.84575  -1.83769  -11.21688 1.000 35.44762 ? 52  GLN A O   1 
ATOM   413  C  CB  . GLN A 1 54  ? 35.15607  -4.19338  -10.97484 1.000 41.36009 ? 52  GLN A CB  1 
ATOM   414  C  CG  . GLN A 1 54  ? 35.91785  -2.89449  -11.12071 1.000 39.09792 ? 52  GLN A CG  1 
ATOM   415  C  CD  . GLN A 1 54  ? 37.29511  -3.06871  -11.73486 1.000 41.82459 ? 52  GLN A CD  1 
ATOM   416  O  OE1 . GLN A 1 54  ? 37.51131  -3.94265  -12.57596 1.000 40.36876 ? 52  GLN A OE1 1 
ATOM   417  N  NE2 . GLN A 1 54  ? 38.23661  -2.20857  -11.33111 1.000 42.53220 ? 52  GLN A NE2 1 
ATOM   418  N  N   . VAL A 1 55  ? 32.57295  -3.59211  -12.61397 1.000 40.56940 ? 53  VAL A N   1 
ATOM   419  C  CA  . VAL A 1 55  ? 32.05928  -2.75816  -13.69176 1.000 38.68068 ? 53  VAL A CA  1 
ATOM   420  C  C   . VAL A 1 55  ? 30.73369  -2.11419  -13.29389 1.000 38.07705 ? 53  VAL A C   1 
ATOM   421  O  O   . VAL A 1 55  ? 30.46663  -0.96139  -13.64737 1.000 35.26050 ? 53  VAL A O   1 
ATOM   422  C  CB  . VAL A 1 55  ? 31.96154  -3.59710  -14.98331 1.000 37.77596 ? 53  VAL A CB  1 
ATOM   423  C  CG1 . VAL A 1 55  ? 30.92661  -3.02245  -15.94035 1.000 36.65758 ? 53  VAL A CG1 1 
ATOM   424  C  CG2 . VAL A 1 55  ? 33.33852  -3.61845  -15.66436 1.000 35.86287 ? 53  VAL A CG2 1 
ATOM   425  N  N   . THR A 1 56  ? 29.89310  -2.82343  -12.52745 1.000 36.97760 ? 54  THR A N   1 
ATOM   426  C  CA  . THR A 1 56  ? 28.64874  -2.19129  -12.09488 1.000 36.99461 ? 54  THR A CA  1 
ATOM   427  C  C   . THR A 1 56  ? 28.92007  -0.99443  -11.18860 1.000 35.98996 ? 54  THR A C   1 
ATOM   428  O  O   . THR A 1 56  ? 28.16127  -0.02422  -11.21818 1.000 36.88071 ? 54  THR A O   1 
ATOM   429  C  CB  . THR A 1 56  ? 27.73935  -3.18114  -11.37112 1.000 37.29221 ? 54  THR A CB  1 
ATOM   430  O  OG1 . THR A 1 56  ? 28.42120  -3.68652  -10.22339 1.000 40.94066 ? 54  THR A OG1 1 
ATOM   431  C  CG2 . THR A 1 56  ? 27.34368  -4.33503  -12.28980 1.000 34.58438 ? 54  THR A CG2 1 
ATOM   432  N  N   . HIS A 1 57  ? 29.99570  -1.04363  -10.39588 1.000 36.46785 ? 55  HIS A N   1 
ATOM   433  C  CA  . HIS A 1 57  ? 30.35936  0.08160   -9.53580  1.000 38.68217 ? 55  HIS A CA  1 
ATOM   434  C  C   . HIS A 1 57  ? 30.90295  1.23449   -10.35794 1.000 40.36267 ? 55  HIS A C   1 
ATOM   435  O  O   . HIS A 1 57  ? 30.55877  2.40438   -10.12642 1.000 41.76701 ? 55  HIS A O   1 
ATOM   436  C  CB  . HIS A 1 57  ? 31.41189  -0.33803  -8.51395  1.000 38.59277 ? 55  HIS A CB  1 
ATOM   437  C  CG  . HIS A 1 57  ? 30.88002  -1.15046  -7.37626  1.000 38.80647 ? 55  HIS A CG  1 
ATOM   438  N  ND1 . HIS A 1 57  ? 30.71376  -2.52193  -7.44778  1.000 41.66058 ? 55  HIS A ND1 1 
ATOM   439  C  CD2 . HIS A 1 57  ? 30.50672  -0.79041  -6.12542  1.000 37.22675 ? 55  HIS A CD2 1 
ATOM   440  C  CE1 . HIS A 1 57  ? 30.25066  -2.96383  -6.29186  1.000 39.41311 ? 55  HIS A CE1 1 
ATOM   441  N  NE2 . HIS A 1 57  ? 30.12005  -1.93377  -5.47357  1.000 38.53568 ? 55  HIS A NE2 1 
ATOM   442  N  N   . LEU A 1 58  ? 31.79137  0.93160   -11.30498 1.000 38.76919 ? 56  LEU A N   1 
ATOM   443  C  CA  . LEU A 1 58  ? 32.39797  2.01250   -12.05442 1.000 37.11973 ? 56  LEU A CA  1 
ATOM   444  C  C   . LEU A 1 58  ? 31.34797  2.74579   -12.87629 1.000 37.79034 ? 56  LEU A C   1 
ATOM   445  O  O   . LEU A 1 58  ? 31.38211  3.98176   -12.98073 1.000 35.17721 ? 56  LEU A O   1 
ATOM   446  C  CB  . LEU A 1 58  ? 33.52074  1.47540   -12.93302 1.000 39.18768 ? 56  LEU A CB  1 
ATOM   447  C  CG  . LEU A 1 58  ? 34.70894  0.84279   -12.19487 1.000 39.99195 ? 56  LEU A CG  1 
ATOM   448  C  CD1 . LEU A 1 58  ? 35.80481  0.58540   -13.20044 1.000 38.36649 ? 56  LEU A CD1 1 
ATOM   449  C  CD2 . LEU A 1 58  ? 35.21845  1.69892   -11.02832 1.000 42.00424 ? 56  LEU A CD2 1 
ATOM   450  N  N   . ILE A 1 59  ? 30.39744  2.00169   -13.45141 1.000 35.54209 ? 57  ILE A N   1 
ATOM   451  C  CA  . ILE A 1 59  ? 29.29052  2.62455   -14.17627 1.000 35.30973 ? 57  ILE A CA  1 
ATOM   452  C  C   . ILE A 1 59  ? 28.49976  3.53592   -13.24892 1.000 37.12097 ? 57  ILE A C   1 
ATOM   453  O  O   . ILE A 1 59  ? 28.17815  4.68429   -13.59704 1.000 33.27815 ? 57  ILE A O   1 
ATOM   454  C  CB  . ILE A 1 59  ? 28.38357  1.55592   -14.80876 1.000 37.00209 ? 57  ILE A CB  1 
ATOM   455  C  CG1 . ILE A 1 59  ? 29.00439  1.03992   -16.10269 1.000 37.56181 ? 57  ILE A CG1 1 
ATOM   456  C  CG2 . ILE A 1 59  ? 26.99142  2.13288   -15.10483 1.000 33.03175 ? 57  ILE A CG2 1 
ATOM   457  C  CD1 . ILE A 1 59  ? 28.44855  -0.31207  -16.53416 1.000 34.44826 ? 57  ILE A CD1 1 
ATOM   458  N  N   . THR A 1 60  ? 28.19904  3.04410   -12.04866 1.000 34.54349 ? 58  THR A N   1 
ATOM   459  C  CA  . THR A 1 60  ? 27.47541  3.84166   -11.06861 1.000 34.60968 ? 58  THR A CA  1 
ATOM   460  C  C   . THR A 1 60  ? 28.23205  5.11110   -10.72487 1.000 36.57534 ? 58  THR A C   1 
ATOM   461  O  O   . THR A 1 60  ? 27.63705  6.19364   -10.66644 1.000 35.73166 ? 58  THR A O   1 
ATOM   462  C  CB  . THR A 1 60  ? 27.22196  3.02923   -9.79920  1.000 36.88288 ? 58  THR A CB  1 
ATOM   463  O  OG1 . THR A 1 60  ? 26.28499  1.97292   -10.06601 1.000 36.72725 ? 58  THR A OG1 1 
ATOM   464  C  CG2 . THR A 1 60  ? 26.66373  3.92723   -8.70658  1.000 34.55433 ? 58  THR A CG2 1 
ATOM   465  N  N   . GLU A 1 61  ? 29.54493  5.00745   -10.49984 1.000 36.23686 ? 59  GLU A N   1 
ATOM   466  C  CA  . GLU A 1 61  ? 30.29083  6.18958   -10.05445 1.000 37.83264 ? 59  GLU A CA  1 
ATOM   467  C  C   . GLU A 1 61  ? 30.44053  7.21884   -11.16814 1.000 37.68490 ? 59  GLU A C   1 
ATOM   468  O  O   . GLU A 1 61  ? 30.47609  8.42785   -10.89665 1.000 35.06623 ? 59  GLU A O   1 
ATOM   469  C  CB  . GLU A 1 61  ? 31.66504  5.78042   -9.51794  1.000 37.23563 ? 59  GLU A CB  1 
ATOM   470  C  CG  . GLU A 1 61  ? 31.57534  4.91734   -8.24270  1.000 40.15232 ? 59  GLU A CG  1 
ATOM   471  C  CD  . GLU A 1 61  ? 31.27322  5.72990   -6.98476  1.000 39.97281 ? 59  GLU A CD  1 
ATOM   472  O  OE1 . GLU A 1 61  ? 31.45366  6.96346   -6.99406  1.000 40.84850 ? 59  GLU A OE1 1 
ATOM   473  O  OE2 . GLU A 1 61  ? 30.85418  5.13528   -5.97988  1.000 39.15775 ? 59  GLU A OE2 1 
ATOM   474  N  N   . TYR A 1 62  ? 30.53453  6.76952   -12.42431 1.000 34.93574 ? 60  TYR A N   1 
ATOM   475  C  CA  . TYR A 1 62  ? 30.56063  7.72372   -13.52498 1.000 33.93216 ? 60  TYR A CA  1 
ATOM   476  C  C   . TYR A 1 62  ? 29.23607  8.47663   -13.61199 1.000 33.29032 ? 60  TYR A C   1 
ATOM   477  O  O   . TYR A 1 62  ? 29.21452  9.68691   -13.85428 1.000 34.37591 ? 60  TYR A O   1 
ATOM   478  C  CB  . TYR A 1 62  ? 30.85614  7.01219   -14.85108 1.000 34.29598 ? 60  TYR A CB  1 
ATOM   479  C  CG  . TYR A 1 62  ? 32.32962  6.87203   -15.22132 1.000 39.22156 ? 60  TYR A CG  1 
ATOM   480  C  CD1 . TYR A 1 62  ? 33.27003  7.80504   -14.82932 1.000 44.02775 ? 60  TYR A CD1 1 
ATOM   481  C  CD2 . TYR A 1 62  ? 32.77296  5.79258   -15.98058 1.000 42.77592 ? 60  TYR A CD2 1 
ATOM   482  C  CE1 . TYR A 1 62  ? 34.62217  7.67521   -15.18432 1.000 43.46778 ? 60  TYR A CE1 1 
ATOM   483  C  CE2 . TYR A 1 62  ? 34.10858  5.67027   -16.33349 1.000 40.76460 ? 60  TYR A CE2 1 
ATOM   484  C  CZ  . TYR A 1 62  ? 35.02605  6.60132   -15.91635 1.000 45.36047 ? 60  TYR A CZ  1 
ATOM   485  O  OH  . TYR A 1 62  ? 36.34545  6.46177   -16.27578 1.000 50.43186 ? 60  TYR A OH  1 
ATOM   486  N  N   . ALA A 1 63  ? 28.11905  7.76279   -13.46153 1.000 33.70093 ? 61  ALA A N   1 
ATOM   487  C  CA  . ALA A 1 63  ? 26.81783  8.42326   -13.48124 1.000 35.73448 ? 61  ALA A CA  1 
ATOM   488  C  C   . ALA A 1 63  ? 26.69769  9.42724   -12.34912 1.000 33.37001 ? 61  ALA A C   1 
ATOM   489  O  O   . ALA A 1 63  ? 26.20447  10.54278  -12.55647 1.000 33.56407 ? 61  ALA A O   1 
ATOM   490  C  CB  . ALA A 1 63  ? 25.69275  7.39044   -13.38486 1.000 28.56550 ? 61  ALA A CB  1 
ATOM   491  N  N   . TRP A 1 64  ? 27.17692  9.06845   -11.15268 1.000 31.72026 ? 62  TRP A N   1 
ATOM   492  C  CA  . TRP A 1 64  ? 27.01991  9.96823   -9.99841  1.000 34.08717 ? 62  TRP A CA  1 
ATOM   493  C  C   . TRP A 1 64  ? 27.95323  11.17505  -10.07978 1.000 36.24600 ? 62  TRP A C   1 
ATOM   494  O  O   . TRP A 1 64  ? 27.59193  12.28082  -9.64500  1.000 35.12044 ? 62  TRP A O   1 
ATOM   495  C  CB  . TRP A 1 64  ? 27.26195  9.20680   -8.68393  1.000 33.46228 ? 62  TRP A CB  1 
ATOM   496  C  CG  . TRP A 1 64  ? 26.05499  8.54939   -8.11858  1.000 36.18768 ? 62  TRP A CG  1 
ATOM   497  C  CD1 . TRP A 1 64  ? 24.75320  8.85470   -8.38520  1.000 35.29537 ? 62  TRP A CD1 1 
ATOM   498  C  CD2 . TRP A 1 64  ? 26.02996  7.44845   -7.18297  1.000 33.83551 ? 62  TRP A CD2 1 
ATOM   499  N  NE1 . TRP A 1 64  ? 23.91852  8.01369   -7.66563  1.000 34.52812 ? 62  TRP A NE1 1 
ATOM   500  C  CE2 . TRP A 1 64  ? 24.68059  7.14929   -6.92480  1.000 34.41534 ? 62  TRP A CE2 1 
ATOM   501  C  CE3 . TRP A 1 64  ? 27.02486  6.70438   -6.53013  1.000 34.22346 ? 62  TRP A CE3 1 
ATOM   502  C  CZ2 . TRP A 1 64  ? 24.29429  6.12709   -6.05366  1.000 35.52568 ? 62  TRP A CZ2 1 
ATOM   503  C  CZ3 . TRP A 1 64  ? 26.64320  5.69034   -5.66290  1.000 35.01040 ? 62  TRP A CZ3 1 
ATOM   504  C  CH2 . TRP A 1 64  ? 25.29278  5.40434   -5.44097  1.000 36.32238 ? 62  TRP A CH2 1 
ATOM   505  N  N   . VAL A 1 65  ? 29.16262  11.00491  -10.62162 1.000 36.94541 ? 63  VAL A N   1 
ATOM   506  C  CA  . VAL A 1 65  ? 29.97725  12.20496  -10.78298 1.000 38.81069 ? 63  VAL A CA  1 
ATOM   507  C  C   . VAL A 1 65  ? 29.35175  13.11885  -11.83170 1.000 37.32479 ? 63  VAL A C   1 
ATOM   508  O  O   . VAL A 1 65  ? 29.52444  14.34057  -11.77925 1.000 38.46036 ? 63  VAL A O   1 
ATOM   509  C  CB  . VAL A 1 65  ? 31.45004  11.88357  -11.11591 1.000 38.51266 ? 63  VAL A CB  1 
ATOM   510  C  CG1 . VAL A 1 65  ? 31.58736  11.28982  -12.51179 1.000 36.61320 ? 63  VAL A CG1 1 
ATOM   511  C  CG2 . VAL A 1 65  ? 32.30425  13.17315  -10.99378 1.000 40.87547 ? 63  VAL A CG2 1 
ATOM   512  N  N   . GLN A 1 66  ? 28.60257  12.55483  -12.78247 1.000 37.76952 ? 64  GLN A N   1 
ATOM   513  C  CA  . GLN A 1 66  ? 27.93432  13.39059  -13.76786 1.000 36.16637 ? 64  GLN A CA  1 
ATOM   514  C  C   . GLN A 1 66  ? 26.68190  14.01521  -13.16958 1.000 33.27542 ? 64  GLN A C   1 
ATOM   515  O  O   . GLN A 1 66  ? 26.35443  15.16659  -13.47690 1.000 34.09429 ? 64  GLN A O   1 
ATOM   516  C  CB  . GLN A 1 66  ? 27.60693  12.58632  -15.04297 1.000 34.59898 ? 64  GLN A CB  1 
ATOM   517  C  CG  . GLN A 1 66  ? 27.19001  13.49012  -16.24833 1.000 33.93646 ? 64  GLN A CG  1 
ATOM   518  C  CD  . GLN A 1 66  ? 28.24652  14.52684  -16.61069 1.000 34.00374 ? 64  GLN A CD  1 
ATOM   519  O  OE1 . GLN A 1 66  ? 29.44010  14.23301  -16.54757 1.000 37.55254 ? 64  GLN A OE1 1 
ATOM   520  N  NE2 . GLN A 1 66  ? 27.81605  15.73228  -17.03529 1.000 32.65872 ? 64  GLN A NE2 1 
ATOM   521  N  N   . VAL A 1 67  ? 26.01124  13.30853  -12.26452 1.000 35.15819 ? 65  VAL A N   1 
ATOM   522  C  CA  . VAL A 1 67  ? 24.93363  13.93321  -11.50487 1.000 34.89324 ? 65  VAL A CA  1 
ATOM   523  C  C   . VAL A 1 67  ? 25.45821  15.16947  -10.77876 1.000 35.80047 ? 65  VAL A C   1 
ATOM   524  O  O   . VAL A 1 67  ? 24.82939  16.23621  -10.79651 1.000 31.37771 ? 65  VAL A O   1 
ATOM   525  C  CB  . VAL A 1 67  ? 24.30507  12.92369  -10.52900 1.000 34.67233 ? 65  VAL A CB  1 
ATOM   526  C  CG1 . VAL A 1 67  ? 23.49596  13.65416  -9.42193  1.000 33.44343 ? 65  VAL A CG1 1 
ATOM   527  C  CG2 . VAL A 1 67  ? 23.39937  11.95630  -11.28134 1.000 32.15129 ? 65  VAL A CG2 1 
ATOM   528  N  N   . HIS A 1 68  ? 26.63896  15.04854  -10.16022 1.000 34.84223 ? 66  HIS A N   1 
ATOM   529  C  CA  . HIS A 1 68  ? 27.21751  16.15588  -9.39457  1.000 36.43113 ? 66  HIS A CA  1 
ATOM   530  C  C   . HIS A 1 68  ? 27.51925  17.34338  -10.30046 1.000 37.59994 ? 66  HIS A C   1 
ATOM   531  O  O   . HIS A 1 68  ? 27.23100  18.50319  -9.96675  1.000 36.77107 ? 66  HIS A O   1 
ATOM   532  C  CB  . HIS A 1 68  ? 28.49372  15.66992  -8.70615  1.000 37.27136 ? 66  HIS A CB  1 
ATOM   533  C  CG  . HIS A 1 68  ? 29.06143  16.62565  -7.70358  1.000 41.70919 ? 66  HIS A CG  1 
ATOM   534  N  ND1 . HIS A 1 68  ? 30.04087  17.54511  -8.02067  1.000 43.50107 ? 66  HIS A ND1 1 
ATOM   535  C  CD2 . HIS A 1 68  ? 28.83289  16.76299  -6.37476  1.000 40.09567 ? 66  HIS A CD2 1 
ATOM   536  C  CE1 . HIS A 1 68  ? 30.36298  18.23098  -6.93879  1.000 43.62372 ? 66  HIS A CE1 1 
ATOM   537  N  NE2 . HIS A 1 68  ? 29.65028  17.77108  -5.92587  1.000 40.19521 ? 66  HIS A NE2 1 
ATOM   538  N  N   . TYR A 1 69  ? 28.14064  17.06629  -11.44705 1.000 37.45378 ? 67  TYR A N   1 
ATOM   539  C  CA  . TYR A 1 69  ? 28.47079  18.11509  -12.38989 1.000 32.24315 ? 67  TYR A CA  1 
ATOM   540  C  C   . TYR A 1 69  ? 27.23018  18.87580  -12.82165 1.000 34.22760 ? 67  TYR A C   1 
ATOM   541  O  O   . TYR A 1 69  ? 27.24556  20.11091  -12.89613 1.000 34.59649 ? 67  TYR A O   1 
ATOM   542  C  CB  . TYR A 1 69  ? 29.15759  17.49883  -13.60003 1.000 34.46064 ? 67  TYR A CB  1 
ATOM   543  C  CG  . TYR A 1 69  ? 29.81801  18.45658  -14.53761 1.000 33.14952 ? 67  TYR A CG  1 
ATOM   544  C  CD1 . TYR A 1 69  ? 31.13150  18.87012  -14.33308 1.000 37.46892 ? 67  TYR A CD1 1 
ATOM   545  C  CD2 . TYR A 1 69  ? 29.15055  18.90578  -15.66507 1.000 34.61096 ? 67  TYR A CD2 1 
ATOM   546  C  CE1 . TYR A 1 69  ? 31.75051  19.72610  -15.21796 1.000 35.11253 ? 67  TYR A CE1 1 
ATOM   547  C  CE2 . TYR A 1 69  ? 29.75370  19.74341  -16.55372 1.000 36.25181 ? 67  TYR A CE2 1 
ATOM   548  C  CZ  . TYR A 1 69  ? 31.04688  20.16910  -16.31939 1.000 37.06638 ? 67  TYR A CZ  1 
ATOM   549  O  OH  . TYR A 1 69  ? 31.62872  21.00891  -17.22986 1.000 36.10739 ? 67  TYR A OH  1 
ATOM   550  N  N   . GLU A 1 70  ? 26.14841  18.15412  -13.12465 1.000 32.28782 ? 68  GLU A N   1 
ATOM   551  C  CA  . GLU A 1 70  ? 24.93540  18.81994  -13.58299 1.000 35.19636 ? 68  GLU A CA  1 
ATOM   552  C  C   . GLU A 1 70  ? 24.24720  19.56345  -12.44195 1.000 34.73213 ? 68  GLU A C   1 
ATOM   553  O  O   . GLU A 1 70  ? 23.59869  20.58704  -12.67573 1.000 33.88794 ? 68  GLU A O   1 
ATOM   554  C  CB  . GLU A 1 70  ? 23.99627  17.79153  -14.24387 1.000 34.00720 ? 68  GLU A CB  1 
ATOM   555  C  CG  . GLU A 1 70  ? 24.66191  16.91285  -15.36050 1.000 31.69821 ? 68  GLU A CG  1 
ATOM   556  C  CD  . GLU A 1 70  ? 25.13151  17.71340  -16.58808 1.000 35.89823 ? 68  GLU A CD  1 
ATOM   557  O  OE1 . GLU A 1 70  ? 25.09129  18.95534  -16.55230 1.000 37.14573 ? 68  GLU A OE1 1 
ATOM   558  O  OE2 . GLU A 1 70  ? 25.57327  17.10729  -17.59401 1.000 33.65095 ? 68  GLU A OE2 1 
ATOM   559  N  N   . LEU A 1 71  ? 24.39778  19.08664  -11.20229 1.000 32.38068 ? 69  LEU A N   1 
ATOM   560  C  CA  . LEU A 1 71  ? 23.77415  19.78113  -10.07920 1.000 32.48744 ? 69  LEU A CA  1 
ATOM   561  C  C   . LEU A 1 71  ? 24.46342  21.10610  -9.79974  1.000 35.28461 ? 69  LEU A C   1 
ATOM   562  O  O   . LEU A 1 71  ? 23.80350  22.09160  -9.44983  1.000 35.45925 ? 69  LEU A O   1 
ATOM   563  C  CB  . LEU A 1 71  ? 23.79140  18.89655  -8.82980  1.000 31.07198 ? 69  LEU A CB  1 
ATOM   564  C  CG  . LEU A 1 71  ? 22.74303  17.77593  -8.83082  1.000 35.63428 ? 69  LEU A CG  1 
ATOM   565  C  CD1 . LEU A 1 71  ? 22.76109  17.00680  -7.50456  1.000 34.14361 ? 69  LEU A CD1 1 
ATOM   566  C  CD2 . LEU A 1 71  ? 21.35592  18.34183  -9.12122  1.000 36.75438 ? 69  LEU A CD2 1 
ATOM   567  N  N   . ARG A 1 72  ? 25.79385  21.13881  -9.91510  1.000 35.91255 ? 70  ARG A N   1 
ATOM   568  C  CA  . ARG A 1 72  ? 26.51565  22.40111  -9.81553  1.000 36.26910 ? 70  ARG A CA  1 
ATOM   569  C  C   . ARG A 1 72  ? 26.02151  23.38884  -10.85676 1.000 38.34293 ? 70  ARG A C   1 
ATOM   570  O  O   . ARG A 1 72  ? 25.86447  24.58902  -10.57265 1.000 35.53030 ? 70  ARG A O   1 
ATOM   571  C  CB  . ARG A 1 72  ? 28.00619  22.15549  -10.00195 1.000 40.29105 ? 70  ARG A CB  1 
ATOM   572  C  CG  . ARG A 1 72  ? 28.67211  21.47582  -8.84098  1.000 45.71247 ? 70  ARG A CG  1 
ATOM   573  C  CD  . ARG A 1 72  ? 30.10005  21.93090  -8.80824  1.000 52.96822 ? 70  ARG A CD  1 
ATOM   574  N  NE  . ARG A 1 72  ? 30.86964  21.05718  -9.66338  1.000 50.56297 ? 70  ARG A NE  1 
ATOM   575  C  CZ  . ARG A 1 72  ? 31.87231  21.42381  -10.44418 1.000 51.41816 ? 70  ARG A CZ  1 
ATOM   576  N  NH1 . ARG A 1 72  ? 32.26722  22.68301  -10.52647 1.000 49.21991 ? 70  ARG A NH1 1 
ATOM   577  N  NH2 . ARG A 1 72  ? 32.48698  20.49671  -11.17423 1.000 46.21633 ? 70  ARG A NH2 1 
ATOM   578  N  N   . ARG A 1 73  ? 25.79380  22.90319  -12.07946 1.000 34.24161 ? 71  ARG A N   1 
ATOM   579  C  CA  . ARG A 1 73  ? 25.23081  23.76131  -13.11567 1.000 39.01491 ? 71  ARG A CA  1 
ATOM   580  C  C   . ARG A 1 73  ? 23.84917  24.25496  -12.71057 1.000 34.41068 ? 71  ARG A C   1 
ATOM   581  O  O   . ARG A 1 73  ? 23.51821  25.43048  -12.91210 1.000 35.92709 ? 71  ARG A O   1 
ATOM   582  C  CB  . ARG A 1 73  ? 25.18434  23.00113  -14.45009 1.000 33.57809 ? 71  ARG A CB  1 
ATOM   583  C  CG  . ARG A 1 73  ? 26.52759  22.89805  -15.11366 1.000 33.40474 ? 71  ARG A CG  1 
ATOM   584  C  CD  . ARG A 1 73  ? 26.48043  22.01060  -16.34174 1.000 34.33869 ? 71  ARG A CD  1 
ATOM   585  N  NE  . ARG A 1 73  ? 25.90692  22.65750  -17.51190 1.000 34.91842 ? 71  ARG A NE  1 
ATOM   586  C  CZ  . ARG A 1 73  ? 25.53292  22.00861  -18.61176 1.000 37.56186 ? 71  ARG A CZ  1 
ATOM   587  N  NH1 . ARG A 1 73  ? 25.61021  20.69477  -18.69795 1.000 35.25202 ? 71  ARG A NH1 1 
ATOM   588  N  NH2 . ARG A 1 73  ? 25.04935  22.69611  -19.64247 1.000 38.36093 ? 71  ARG A NH2 1 
ATOM   589  N  N   . ALA A 1 74  ? 23.05369  23.38211  -12.07825 1.000 32.91691 ? 72  ALA A N   1 
ATOM   590  C  CA  . ALA A 1 74  ? 21.71344  23.77555  -11.65608 1.000 35.95689 ? 72  ALA A CA  1 
ATOM   591  C  C   . ALA A 1 74  ? 21.76795  24.88733  -10.61350 1.000 35.68374 ? 72  ALA A C   1 
ATOM   592  O  O   . ALA A 1 74  ? 20.93392  25.79491  -10.62669 1.000 32.96658 ? 72  ALA A O   1 
ATOM   593  C  CB  . ALA A 1 74  ? 20.95019  22.57031  -11.11168 1.000 33.12221 ? 72  ALA A CB  1 
ATOM   594  N  N   . ILE A 1 75  ? 22.74921  24.83382  -9.71187  1.000 36.86457 ? 73  ILE A N   1 
ATOM   595  C  CA  . ILE A 1 75  ? 22.93843  25.91775  -8.75175  1.000 38.06984 ? 73  ILE A CA  1 
ATOM   596  C  C   . ILE A 1 75  ? 23.25042  27.21638  -9.47844  1.000 37.49454 ? 73  ILE A C   1 
ATOM   597  O  O   . ILE A 1 75  ? 22.62464  28.25129  -9.22407  1.000 37.51639 ? 73  ILE A O   1 
ATOM   598  C  CB  . ILE A 1 75  ? 24.05240  25.56321  -7.75990  1.000 37.90223 ? 73  ILE A CB  1 
ATOM   599  C  CG1 . ILE A 1 75  ? 23.62404  24.37281  -6.90191  1.000 36.47990 ? 73  ILE A CG1 1 
ATOM   600  C  CG2 . ILE A 1 75  ? 24.40178  26.78843  -6.92177  1.000 36.21815 ? 73  ILE A CG2 1 
ATOM   601  C  CD1 . ILE A 1 75  ? 24.77414  23.76429  -6.14193  1.000 40.43885 ? 73  ILE A CD1 1 
ATOM   602  N  N   . GLY A 1 76  ? 24.22263  27.17181  -10.40502 1.000 36.98830 ? 74  GLY A N   1 
ATOM   603  C  CA  . GLY A 1 76  ? 24.55724  28.35402  -11.18583 1.000 38.68434 ? 74  GLY A CA  1 
ATOM   604  C  C   . GLY A 1 76  ? 23.34535  28.97714  -11.84547 1.000 37.96885 ? 74  GLY A C   1 
ATOM   605  O  O   . GLY A 1 76  ? 23.15249  30.19000  -11.79284 1.000 36.75761 ? 74  GLY A O   1 
ATOM   606  N  N   . HIS A 1 77  ? 22.48834  28.14939  -12.44231 1.000 35.98991 ? 75  HIS A N   1 
ATOM   607  C  CA  . HIS A 1 77  ? 21.30944  28.67441  -13.12606 1.000 35.83105 ? 75  HIS A CA  1 
ATOM   608  C  C   . HIS A 1 77  ? 20.33819  29.30129  -12.13575 1.000 35.42810 ? 75  HIS A C   1 
ATOM   609  O  O   . HIS A 1 77  ? 19.86325  30.42633  -12.33392 1.000 32.66230 ? 75  HIS A O   1 
ATOM   610  C  CB  . HIS A 1 77  ? 20.61126  27.55089  -13.89809 1.000 31.21907 ? 75  HIS A CB  1 
ATOM   611  C  CG  . HIS A 1 77  ? 21.35220  27.10109  -15.11691 1.000 33.54454 ? 75  HIS A CG  1 
ATOM   612  N  ND1 . HIS A 1 77  ? 21.84649  27.98423  -16.05438 1.000 35.54903 ? 75  HIS A ND1 1 
ATOM   613  C  CD2 . HIS A 1 77  ? 21.66830  25.86042  -15.56104 1.000 31.88789 ? 75  HIS A CD2 1 
ATOM   614  C  CE1 . HIS A 1 77  ? 22.44264  27.30622  -17.02164 1.000 33.57483 ? 75  HIS A CE1 1 
ATOM   615  N  NE2 . HIS A 1 77  ? 22.33887  26.01410  -16.74836 1.000 34.47404 ? 75  HIS A NE2 1 
ATOM   616  N  N   . LEU A 1 78  ? 20.00673  28.55752  -11.07548 1.000 34.09090 ? 76  LEU A N   1 
ATOM   617  C  CA  . LEU A 1 78  ? 19.02342  29.03195  -10.10737 1.000 34.78761 ? 76  LEU A CA  1 
ATOM   618  C  C   . LEU A 1 78  ? 19.46064  30.35003  -9.47240  1.000 37.37553 ? 76  LEU A C   1 
ATOM   619  O  O   . LEU A 1 78  ? 18.63183  31.24669  -9.25760  1.000 33.99404 ? 76  LEU A O   1 
ATOM   620  C  CB  . LEU A 1 78  ? 18.78634  27.94921  -9.05125  1.000 33.73098 ? 76  LEU A CB  1 
ATOM   621  C  CG  . LEU A 1 78  ? 17.89483  26.78806  -9.48789  1.000 31.11134 ? 76  LEU A CG  1 
ATOM   622  C  CD1 . LEU A 1 78  ? 17.88092  25.69581  -8.41467  1.000 31.05172 ? 76  LEU A CD1 1 
ATOM   623  C  CD2 . LEU A 1 78  ? 16.46061  27.24671  -9.78411  1.000 29.91498 ? 76  LEU A CD2 1 
ATOM   624  N  N   . ASP A 1 79  ? 20.76555  30.49784  -9.20758  1.000 37.17936 ? 77  ASP A N   1 
ATOM   625  C  CA  . ASP A 1 79  ? 21.28116  31.72219  -8.60118  1.000 35.64374 ? 77  ASP A CA  1 
ATOM   626  C  C   . ASP A 1 79  ? 21.08283  32.92684  -9.51213  1.000 38.61712 ? 77  ASP A C   1 
ATOM   627  O  O   . ASP A 1 79  ? 20.99562  34.06036  -9.02845  1.000 37.97933 ? 77  ASP A O   1 
ATOM   628  C  CB  . ASP A 1 79  ? 22.76803  31.55922  -8.27309  1.000 37.49724 ? 77  ASP A CB  1 
ATOM   629  C  CG  . ASP A 1 79  ? 23.02252  30.81908  -6.96736  1.000 40.17410 ? 77  ASP A CG  1 
ATOM   630  O  OD1 . ASP A 1 79  ? 22.07194  30.59637  -6.17432  1.000 38.75550 ? 77  ASP A OD1 1 
ATOM   631  O  OD2 . ASP A 1 79  ? 24.19778  30.44725  -6.73845  1.000 38.95532 ? 77  ASP A OD2 1 
ATOM   632  N  N   . GLU A 1 80  ? 21.03017  32.71753  -10.82665 1.000 34.50067 ? 78  GLU A N   1 
ATOM   633  C  CA  . GLU A 1 80  ? 20.81142  33.80112  -11.77140 1.000 37.13884 ? 78  GLU A CA  1 
ATOM   634  C  C   . GLU A 1 80  ? 19.39608  33.81394  -12.30827 1.000 36.53224 ? 78  GLU A C   1 
ATOM   635  O  O   . GLU A 1 80  ? 19.14628  34.44397  -13.34076 1.000 36.75008 ? 78  GLU A O   1 
ATOM   636  C  CB  . GLU A 1 80  ? 21.79361  33.70877  -12.93662 1.000 35.36199 ? 78  GLU A CB  1 
ATOM   637  C  CG  . GLU A 1 80  ? 23.25188  33.74296  -12.52280 1.000 41.63339 ? 78  GLU A CG  1 
ATOM   638  C  CD  . GLU A 1 80  ? 23.65827  35.05875  -11.85642 1.000 48.85146 ? 78  GLU A CD  1 
ATOM   639  O  OE1 . GLU A 1 80  ? 23.06549  36.11535  -12.17371 1.000 45.97163 ? 78  GLU A OE1 1 
ATOM   640  O  OE2 . GLU A 1 80  ? 24.59575  35.03521  -11.03153 1.000 57.36851 ? 78  GLU A OE2 1 
ATOM   641  N  N   . ASP A 1 81  ? 18.48449  33.08647  -11.66513 1.000 35.23909 ? 79  ASP A N   1 
ATOM   642  C  CA  . ASP A 1 81  ? 17.06660  33.04815  -12.04181 1.000 36.53550 ? 79  ASP A CA  1 
ATOM   643  C  C   . ASP A 1 81  ? 16.84020  32.48091  -13.44377 1.000 39.02423 ? 79  ASP A C   1 
ATOM   644  O  O   . ASP A 1 81  ? 15.85346  32.82128  -14.10242 1.000 37.69182 ? 79  ASP A O   1 
ATOM   645  C  CB  . ASP A 1 81  ? 16.42312  34.42809  -11.92804 1.000 37.50289 ? 79  ASP A CB  1 
ATOM   646  C  CG  . ASP A 1 81  ? 16.63967  35.04877  -10.56076 1.000 40.63253 ? 79  ASP A CG  1 
ATOM   647  O  OD1 . ASP A 1 81  ? 16.29733  34.38774  -9.55542  1.000 39.33931 ? 79  ASP A OD1 1 
ATOM   648  O  OD2 . ASP A 1 81  ? 17.14392  36.19010  -10.50647 1.000 43.63819 ? 79  ASP A OD2 1 
ATOM   649  N  N   . ARG A 1 82  ? 17.73174  31.60043  -13.90184 1.000 34.36198 ? 80  ARG A N   1 
ATOM   650  C  CA  . ARG A 1 82  ? 17.55958  30.91488  -15.18230 1.000 38.43020 ? 80  ARG A CA  1 
ATOM   651  C  C   . ARG A 1 82  ? 16.84705  29.58409  -14.91600 1.000 34.39431 ? 80  ARG A C   1 
ATOM   652  O  O   . ARG A 1 82  ? 17.45255  28.50981  -14.89250 1.000 30.66152 ? 80  ARG A O   1 
ATOM   653  C  CB  . ARG A 1 82  ? 18.91147  30.71591  -15.86945 1.000 35.74397 ? 80  ARG A CB  1 
ATOM   654  C  CG  . ARG A 1 82  ? 19.74858  32.01809  -15.91470 1.000 35.13242 ? 80  ARG A CG  1 
ATOM   655  C  CD  . ARG A 1 82  ? 21.01295  31.85758  -16.74326 1.000 34.59470 ? 80  ARG A CD  1 
ATOM   656  N  NE  . ARG A 1 82  ? 21.96032  30.88500  -16.20473 1.000 36.30779 ? 80  ARG A NE  1 
ATOM   657  C  CZ  . ARG A 1 82  ? 23.16730  31.16653  -15.72277 1.000 36.57885 ? 80  ARG A CZ  1 
ATOM   658  N  NH1 . ARG A 1 82  ? 23.60652  32.40840  -15.63433 1.000 37.40860 ? 80  ARG A NH1 1 
ATOM   659  N  NH2 . ARG A 1 82  ? 23.95835  30.17128  -15.32622 1.000 39.95421 ? 80  ARG A NH2 1 
ATOM   660  N  N   . TYR A 1 83  ? 15.52391  29.67090  -14.73947 1.000 33.29590 ? 81  TYR A N   1 
ATOM   661  C  CA  . TYR A 1 83  ? 14.74633  28.51968  -14.27620 1.000 32.45683 ? 81  TYR A CA  1 
ATOM   662  C  C   . TYR A 1 83  ? 14.65284  27.44744  -15.35273 1.000 31.35854 ? 81  TYR A C   1 
ATOM   663  O  O   . TYR A 1 83  ? 14.85795  26.26076  -15.07449 1.000 33.89631 ? 81  TYR A O   1 
ATOM   664  C  CB  . TYR A 1 83  ? 13.32468  28.93935  -13.86460 1.000 31.11161 ? 81  TYR A CB  1 
ATOM   665  C  CG  . TYR A 1 83  ? 13.22288  30.19343  -13.02135 1.000 36.70308 ? 81  TYR A CG  1 
ATOM   666  C  CD1 . TYR A 1 83  ? 13.95034  30.34424  -11.85322 1.000 35.58198 ? 81  TYR A CD1 1 
ATOM   667  C  CD2 . TYR A 1 83  ? 12.36626  31.22616  -13.39670 1.000 38.99707 ? 81  TYR A CD2 1 
ATOM   668  C  CE1 . TYR A 1 83  ? 13.82314  31.51725  -11.07580 1.000 35.95377 ? 81  TYR A CE1 1 
ATOM   669  C  CE2 . TYR A 1 83  ? 12.24167  32.37400  -12.63920 1.000 37.23496 ? 81  TYR A CE2 1 
ATOM   670  C  CZ  . TYR A 1 83  ? 12.96467  32.50714  -11.47325 1.000 39.32036 ? 81  TYR A CZ  1 
ATOM   671  O  OH  . TYR A 1 83  ? 12.83498  33.67019  -10.71133 1.000 44.86025 ? 81  TYR A OH  1 
ATOM   672  N  N   . HIS A 1 84  ? 14.30273  27.84458  -16.58188 1.000 32.93769 ? 82  HIS A N   1 
ATOM   673  C  CA  . HIS A 1 84  ? 14.22751  26.87350  -17.67472 1.000 33.47745 ? 82  HIS A CA  1 
ATOM   674  C  C   . HIS A 1 84  ? 15.50604  26.07018  -17.76530 1.000 32.57171 ? 82  HIS A C   1 
ATOM   675  O  O   . HIS A 1 84  ? 15.48083  24.84188  -17.83534 1.000 31.41025 ? 82  HIS A O   1 
ATOM   676  C  CB  . HIS A 1 84  ? 13.96589  27.58073  -19.00034 1.000 30.77825 ? 82  HIS A CB  1 
ATOM   677  C  CG  . HIS A 1 84  ? 12.68125  28.34662  -19.02482 1.000 31.83936 ? 82  HIS A CG  1 
ATOM   678  N  ND1 . HIS A 1 84  ? 12.56770  29.61875  -18.50446 1.000 32.55960 ? 82  HIS A ND1 1 
ATOM   679  C  CD2 . HIS A 1 84  ? 11.45460  28.01537  -19.49709 1.000 29.60383 ? 82  HIS A CD2 1 
ATOM   680  C  CE1 . HIS A 1 84  ? 11.32302  30.03958  -18.66367 1.000 33.81460 ? 82  HIS A CE1 1 
ATOM   681  N  NE2 . HIS A 1 84  ? 10.62407  29.07589  -19.24754 1.000 34.37595 ? 82  HIS A NE2 1 
ATOM   682  N  N   . GLN A 1 85  ? 16.64477  26.75295  -17.76704 1.000 32.81801 ? 83  GLN A N   1 
ATOM   683  C  CA  . GLN A 1 85  ? 17.90452  26.04215  -17.91033 1.000 32.11629 ? 83  GLN A CA  1 
ATOM   684  C  C   . GLN A 1 85  ? 18.17549  25.13501  -16.72210 1.000 30.94103 ? 83  GLN A C   1 
ATOM   685  O  O   . GLN A 1 85  ? 18.78974  24.05977  -16.87484 1.000 30.03183 ? 83  GLN A O   1 
ATOM   686  C  CB  . GLN A 1 85  ? 19.03865  27.04243  -18.09406 1.000 31.49875 ? 83  GLN A CB  1 
ATOM   687  C  CG  . GLN A 1 85  ? 19.04959  27.67404  -19.47395 1.000 30.94272 ? 83  GLN A CG  1 
ATOM   688  C  CD  . GLN A 1 85  ? 19.85796  28.93618  -19.51442 1.000 35.20898 ? 83  GLN A CD  1 
ATOM   689  O  OE1 . GLN A 1 85  ? 19.34425  30.02323  -19.24407 1.000 34.11308 ? 83  GLN A OE1 1 
ATOM   690  N  NE2 . GLN A 1 85  ? 21.14475  28.80716  -19.84698 1.000 34.54533 ? 83  GLN A NE2 1 
ATOM   691  N  N   . ALA A 1 86  ? 17.74203  25.55200  -15.53086 1.000 29.16984 ? 84  ALA A N   1 
ATOM   692  C  CA  . ALA A 1 86  ? 17.86274  24.68819  -14.35983 1.000 33.11992 ? 84  ALA A CA  1 
ATOM   693  C  C   . ALA A 1 86  ? 17.01284  23.41674  -14.49700 1.000 30.97028 ? 84  ALA A C   1 
ATOM   694  O  O   . ALA A 1 86  ? 17.42625  22.34014  -14.05730 1.000 29.28464 ? 84  ALA A O   1 
ATOM   695  C  CB  . ALA A 1 86  ? 17.48161  25.47265  -13.11103 1.000 30.90235 ? 84  ALA A CB  1 
ATOM   696  N  N   . VAL A 1 87  ? 15.81958  23.51946  -15.08709 1.000 30.83406 ? 85  VAL A N   1 
ATOM   697  C  CA  . VAL A 1 87  ? 14.96799  22.34307  -15.26462 1.000 29.57470 ? 85  VAL A CA  1 
ATOM   698  C  C   . VAL A 1 87  ? 15.74514  21.22254  -15.95449 1.000 31.42240 ? 85  VAL A C   1 
ATOM   699  O  O   . VAL A 1 87  ? 15.75951  20.06872  -15.49843 1.000 29.81339 ? 85  VAL A O   1 
ATOM   700  C  CB  . VAL A 1 87  ? 13.70592  22.71184  -16.06856 1.000 30.72787 ? 85  VAL A CB  1 
ATOM   701  C  CG1 . VAL A 1 87  ? 12.85600  21.43639  -16.35767 1.000 31.75281 ? 85  VAL A CG1 1 
ATOM   702  C  CG2 . VAL A 1 87  ? 12.89217  23.73389  -15.33627 1.000 33.13357 ? 85  VAL A CG2 1 
ATOM   703  N  N   . ARG A 1 88  ? 16.41729  21.56506  -17.06071 1.000 30.96054 ? 86  ARG A N   1 
ATOM   704  C  CA  . ARG A 1 88  ? 17.10796  20.58003  -17.88022 1.000 28.79594 ? 86  ARG A CA  1 
ATOM   705  C  C   . ARG A 1 88  ? 18.17895  19.85647  -17.08644 1.000 31.32505 ? 86  ARG A C   1 
ATOM   706  O  O   . ARG A 1 88  ? 18.35785  18.64814  -17.24072 1.000 29.30835 ? 86  ARG A O   1 
ATOM   707  C  CB  . ARG A 1 88  ? 17.73695  21.25190  -19.10525 1.000 30.94838 ? 86  ARG A CB  1 
ATOM   708  C  CG  . ARG A 1 88  ? 16.73070  21.86180  -20.03885 1.000 28.47988 ? 86  ARG A CG  1 
ATOM   709  C  CD  . ARG A 1 88  ? 17.37964  22.17773  -21.38216 1.000 27.06300 ? 86  ARG A CD  1 
ATOM   710  N  NE  . ARG A 1 88  ? 16.43676  22.89995  -22.22996 1.000 30.17927 ? 86  ARG A NE  1 
ATOM   711  C  CZ  . ARG A 1 88  ? 16.36695  24.22292  -22.33864 1.000 31.41643 ? 86  ARG A CZ  1 
ATOM   712  N  NH1 . ARG A 1 88  ? 17.18227  25.02061  -21.65605 1.000 29.64562 ? 86  ARG A NH1 1 
ATOM   713  N  NH2 . ARG A 1 88  ? 15.47234  24.75842  -23.17180 1.000 30.52186 ? 86  ARG A NH2 1 
ATOM   714  N  N   . MET A 1 89  ? 18.90492  20.58218  -16.23939 1.000 29.39591 ? 87  MET A N   1 
ATOM   715  C  CA  . MET A 1 89  ? 19.94898  19.96187  -15.43108 1.000 32.32826 ? 87  MET A CA  1 
ATOM   716  C  C   . MET A 1 89  ? 19.35627  18.93991  -14.45694 1.000 32.68815 ? 87  MET A C   1 
ATOM   717  O  O   . MET A 1 89  ? 19.87981  17.82079  -14.30483 1.000 31.11964 ? 87  MET A O   1 
ATOM   718  C  CB  . MET A 1 89  ? 20.71142  21.06504  -14.69375 1.000 32.00060 ? 87  MET A CB  1 
ATOM   719  C  CG  . MET A 1 89  ? 21.19848  22.19265  -15.62359 1.000 36.47952 ? 87  MET A CG  1 
ATOM   720  S  SD  . MET A 1 89  ? 22.44399  21.69152  -16.81699 1.000 47.16094 ? 87  MET A SD  1 
ATOM   721  C  CE  . MET A 1 89  ? 21.55350  21.22396  -18.31716 1.000 37.82849 ? 87  MET A CE  1 
ATOM   722  N  N   . PHE A 1 90  ? 18.25001  19.29141  -13.80117 1.000 30.98141 ? 88  PHE A N   1 
ATOM   723  C  CA  . PHE A 1 90  ? 17.62364  18.32943  -12.89874 1.000 30.27148 ? 88  PHE A CA  1 
ATOM   724  C  C   . PHE A 1 90  ? 17.12707  17.09577  -13.66137 1.000 31.44937 ? 88  PHE A C   1 
ATOM   725  O  O   . PHE A 1 90  ? 17.33962  15.96914  -13.20906 1.000 32.07752 ? 88  PHE A O   1 
ATOM   726  C  CB  . PHE A 1 90  ? 16.47692  18.96816  -12.11413 1.000 29.80894 ? 88  PHE A CB  1 
ATOM   727  C  CG  . PHE A 1 90  ? 16.93280  19.95395  -11.03486 1.000 34.23990 ? 88  PHE A CG  1 
ATOM   728  C  CD1 . PHE A 1 90  ? 17.66096  19.51886  -9.92461  1.000 35.38820 ? 88  PHE A CD1 1 
ATOM   729  C  CD2 . PHE A 1 90  ? 16.61443  21.29947  -11.13661 1.000 33.80058 ? 88  PHE A CD2 1 
ATOM   730  C  CE1 . PHE A 1 90  ? 18.05641  20.42074  -8.93675  1.000 36.61403 ? 88  PHE A CE1 1 
ATOM   731  C  CE2 . PHE A 1 90  ? 17.01283  22.23937  -10.14185 1.000 32.66362 ? 88  PHE A CE2 1 
ATOM   732  C  CZ  . PHE A 1 90  ? 17.73625  21.79009  -9.05132  1.000 34.49293 ? 88  PHE A CZ  1 
ATOM   733  N  N   . ASP A 1 91  ? 16.49822  17.27893  -14.83376 1.000 30.36288 ? 89  ASP A N   1 
ATOM   734  C  CA  . ASP A 1 91  ? 16.01551  16.11247  -15.59478 1.000 33.49374 ? 89  ASP A CA  1 
ATOM   735  C  C   . ASP A 1 91  ? 17.16936  15.22702  -16.05763 1.000 32.83509 ? 89  ASP A C   1 
ATOM   736  O  O   . ASP A 1 91  ? 17.02984  13.99825  -16.15528 1.000 32.58580 ? 89  ASP A O   1 
ATOM   737  C  CB  . ASP A 1 91  ? 15.20146  16.56389  -16.80957 1.000 31.29976 ? 89  ASP A CB  1 
ATOM   738  C  CG  . ASP A 1 91  ? 13.81118  17.06945  -16.43087 1.000 34.93834 ? 89  ASP A CG  1 
ATOM   739  O  OD1 . ASP A 1 91  ? 13.34749  16.76895  -15.30640 1.000 35.62900 ? 89  ASP A OD1 1 
ATOM   740  O  OD2 . ASP A 1 91  ? 13.19209  17.77937  -17.25302 1.000 33.65224 ? 89  ASP A OD2 1 
ATOM   741  N  N   . ARG A 1 92  ? 18.30001  15.83802  -16.39954 1.000 32.49950 ? 90  ARG A N   1 
ATOM   742  C  CA  . ARG A 1 92  ? 19.45314  15.05936  -16.82961 1.000 33.98132 ? 90  ARG A CA  1 
ATOM   743  C  C   . ARG A 1 92  ? 20.00341  14.25645  -15.66035 1.000 33.00030 ? 90  ARG A C   1 
ATOM   744  O  O   . ARG A 1 92  ? 20.29368  13.05904  -15.79157 1.000 34.24183 ? 90  ARG A O   1 
ATOM   745  C  CB  . ARG A 1 92  ? 20.49420  16.01802  -17.43325 1.000 33.62487 ? 90  ARG A CB  1 
ATOM   746  C  CG  . ARG A 1 92  ? 21.61899  15.35917  -18.17871 1.000 36.76208 ? 90  ARG A CG  1 
ATOM   747  C  CD  . ARG A 1 92  ? 22.69535  16.34665  -18.52202 1.000 30.98689 ? 90  ARG A CD  1 
ATOM   748  N  NE  . ARG A 1 92  ? 22.29635  17.30482  -19.55001 1.000 34.53778 ? 90  ARG A NE  1 
ATOM   749  C  CZ  . ARG A 1 92  ? 23.15697  18.03989  -20.23942 1.000 33.28424 ? 90  ARG A CZ  1 
ATOM   750  N  NH1 . ARG A 1 92  ? 24.46046  17.94142  -20.03567 1.000 33.41018 ? 90  ARG A NH1 1 
ATOM   751  N  NH2 . ARG A 1 92  ? 22.69898  18.92334  -21.12580 1.000 36.63850 ? 90  ARG A NH2 1 
ATOM   752  N  N   . ALA A 1 93  ? 20.09081  14.88555  -14.49069 1.000 31.81211 ? 91  ALA A N   1 
ATOM   753  C  CA  . ALA A 1 93  ? 20.49187  14.16831  -13.28530 1.000 32.18117 ? 91  ALA A CA  1 
ATOM   754  C  C   . ALA A 1 93  ? 19.57454  12.98571  -12.99316 1.000 31.02922 ? 91  ALA A C   1 
ATOM   755  O  O   . ALA A 1 93  ? 20.04724  11.92072  -12.57613 1.000 31.70046 ? 91  ALA A O   1 
ATOM   756  C  CB  . ALA A 1 93  ? 20.50615  15.11993  -12.08883 1.000 33.29378 ? 91  ALA A CB  1 
ATOM   757  N  N   . THR A 1 94  ? 18.25478  13.16430  -13.14692 1.000 30.16123 ? 92  THR A N   1 
ATOM   758  C  CA  . THR A 1 94  ? 17.34742  12.04309  -12.90568 1.000 30.70180 ? 92  THR A CA  1 
ATOM   759  C  C   . THR A 1 94  ? 17.65167  10.87601  -13.85276 1.000 30.41244 ? 92  THR A C   1 
ATOM   760  O  O   . THR A 1 94  ? 17.71166  9.71417   -13.42498 1.000 32.16374 ? 92  THR A O   1 
ATOM   761  C  CB  . THR A 1 94  ? 15.88117  12.49766  -13.03246 1.000 30.40884 ? 92  THR A CB  1 
ATOM   762  O  OG1 . THR A 1 94  ? 15.61909  13.61569  -12.16454 1.000 35.51234 ? 92  THR A OG1 1 
ATOM   763  C  CG2 . THR A 1 94  ? 14.90525  11.36311  -12.68611 1.000 29.96815 ? 92  THR A CG2 1 
ATOM   764  N  N   . GLY A 1 95  ? 17.86998  11.16720  -15.13825 1.000 27.47141 ? 93  GLY A N   1 
ATOM   765  C  CA  . GLY A 1 95  ? 18.22608  10.11773  -16.08165 1.000 26.83104 ? 93  GLY A CA  1 
ATOM   766  C  C   . GLY A 1 95  ? 19.52449  9.41284   -15.72916 1.000 30.75709 ? 93  GLY A C   1 
ATOM   767  O  O   . GLY A 1 95  ? 19.63294  8.19453   -15.87274 1.000 29.66040 ? 93  GLY A O   1 
ATOM   768  N  N   . LEU A 1 96  ? 20.52898  10.15912  -15.26178 1.000 28.64504 ? 94  LEU A N   1 
ATOM   769  C  CA  . LEU A 1 96  ? 21.75067  9.49796   -14.79888 1.000 30.03874 ? 94  LEU A CA  1 
ATOM   770  C  C   . LEU A 1 96  ? 21.49631  8.64767   -13.55867 1.000 32.66178 ? 94  LEU A C   1 
ATOM   771  O  O   . LEU A 1 96  ? 22.05368  7.54262   -13.42633 1.000 32.47693 ? 94  LEU A O   1 
ATOM   772  C  CB  . LEU A 1 96  ? 22.82469  10.53391  -14.50695 1.000 28.87401 ? 94  LEU A CB  1 
ATOM   773  C  CG  . LEU A 1 96  ? 23.30750  11.18510  -15.79071 1.000 30.05272 ? 94  LEU A CG  1 
ATOM   774  C  CD1 . LEU A 1 96  ? 23.77409  12.60010  -15.48678 1.000 33.68979 ? 94  LEU A CD1 1 
ATOM   775  C  CD2 . LEU A 1 96  ? 24.41997  10.38706  -16.40054 1.000 30.91996 ? 94  LEU A CD2 1 
ATOM   776  N  N   . SER A 1 97  ? 20.68120  9.16181   -12.62401 1.000 28.99014 ? 95  SER A N   1 
ATOM   777  C  CA  . SER A 1 97  ? 20.33706  8.37601   -11.44547 1.000 31.53029 ? 95  SER A CA  1 
ATOM   778  C  C   . SER A 1 97  ? 19.67637  7.06102   -11.84287 1.000 35.09067 ? 95  SER A C   1 
ATOM   779  O  O   . SER A 1 97  ? 19.95359  6.01489   -11.23921 1.000 32.89596 ? 95  SER A O   1 
ATOM   780  C  CB  . SER A 1 97  ? 19.42401  9.16534   -10.50344 1.000 30.58887 ? 95  SER A CB  1 
ATOM   781  O  OG  . SER A 1 97  ? 19.02880  8.36192   -9.38195  1.000 31.05705 ? 95  SER A OG  1 
ATOM   782  N  N   . GLU A 1 98  ? 18.81150  7.08904   -12.86457 1.000 32.47235 ? 96  GLU A N   1 
ATOM   783  C  CA  . GLU A 1 98  ? 18.14823  5.85288   -13.28020 1.000 34.52833 ? 96  GLU A CA  1 
ATOM   784  C  C   . GLU A 1 98  ? 19.15061  4.83397   -13.82414 1.000 31.44856 ? 96  GLU A C   1 
ATOM   785  O  O   . GLU A 1 98  ? 18.92444  3.62242   -13.72172 1.000 35.24368 ? 96  GLU A O   1 
ATOM   786  C  CB  . GLU A 1 98  ? 17.06038  6.17548   -14.30466 1.000 33.96428 ? 96  GLU A CB  1 
ATOM   787  C  CG  . GLU A 1 98  ? 15.80679  6.83975   -13.66628 1.000 32.84412 ? 96  GLU A CG  1 
ATOM   788  C  CD  . GLU A 1 98  ? 15.15083  5.89916   -12.64853 1.000 36.17731 ? 96  GLU A CD  1 
ATOM   789  O  OE1 . GLU A 1 98  ? 14.69305  4.81088   -13.05471 1.000 34.77297 ? 96  GLU A OE1 1 
ATOM   790  O  OE2 . GLU A 1 98  ? 15.09631  6.22918   -11.44092 1.000 36.91698 ? 96  GLU A OE2 1 
ATOM   791  N  N   . VAL A 1 99  ? 20.27720  5.29757   -14.36871 1.000 34.74538 ? 97  VAL A N   1 
ATOM   792  C  CA  . VAL A 1 99  ? 21.34555  4.37465   -14.74461 1.000 33.81610 ? 97  VAL A CA  1 
ATOM   793  C  C   . VAL A 1 99  ? 21.91997  3.68849   -13.50702 1.000 33.06814 ? 97  VAL A C   1 
ATOM   794  O  O   . VAL A 1 99  ? 22.15569  2.47574   -13.51356 1.000 32.11293 ? 97  VAL A O   1 
ATOM   795  C  CB  . VAL A 1 99  ? 22.43830  5.09111   -15.55638 1.000 33.53582 ? 97  VAL A CB  1 
ATOM   796  C  CG1 . VAL A 1 99  ? 23.64427  4.15967   -15.75057 1.000 33.36853 ? 97  VAL A CG1 1 
ATOM   797  C  CG2 . VAL A 1 99  ? 21.89410  5.54548   -16.91527 1.000 31.07834 ? 97  VAL A CG2 1 
ATOM   798  N  N   . THR A 1 100 ? 22.15870  4.44045   -12.42851 1.000 31.88051 ? 98  THR A N   1 
ATOM   799  C  CA  . THR A 1 100 ? 22.65876  3.79587   -11.21110 1.000 34.05817 ? 98  THR A CA  1 
ATOM   800  C  C   . THR A 1 100 ? 21.68271  2.74227   -10.70289 1.000 34.86344 ? 98  THR A C   1 
ATOM   801  O  O   . THR A 1 100 ? 22.10073  1.70518   -10.17393 1.000 34.94345 ? 98  THR A O   1 
ATOM   802  C  CB  . THR A 1 100 ? 22.95441  4.82266   -10.10800 1.000 36.01831 ? 98  THR A CB  1 
ATOM   803  O  OG1 . THR A 1 100 ? 21.73600  5.33271   -9.56864  1.000 34.97728 ? 98  THR A OG1 1 
ATOM   804  C  CG2 . THR A 1 100 ? 23.77175  5.98902   -10.64373 1.000 32.44432 ? 98  THR A CG2 1 
ATOM   805  N  N   . VAL A 1 101 ? 20.37853  2.98665   -10.84662 1.000 34.59514 ? 99  VAL A N   1 
ATOM   806  C  CA  . VAL A 1 101 ? 19.39147  1.99644   -10.40887 1.000 32.55406 ? 99  VAL A CA  1 
ATOM   807  C  C   . VAL A 1 101 ? 19.53631  0.71789   -11.22390 1.000 33.80153 ? 99  VAL A C   1 
ATOM   808  O  O   . VAL A 1 101 ? 19.57103  -0.39044  -10.67983 1.000 35.84593 ? 99  VAL A O   1 
ATOM   809  C  CB  . VAL A 1 101 ? 17.96432  2.59161   -10.49559 1.000 31.40338 ? 99  VAL A CB  1 
ATOM   810  C  CG1 . VAL A 1 101 ? 16.87238  1.52141   -10.30879 1.000 37.31421 ? 99  VAL A CG1 1 
ATOM   811  C  CG2 . VAL A 1 101 ? 17.77910  3.71956   -9.48888  1.000 34.56791 ? 99  VAL A CG2 1 
ATOM   812  N  N   . GLN A 1 102 ? 19.68447  0.84072   -12.53481 1.000 34.25968 ? 100 GLN A N   1 
ATOM   813  C  CA  . GLN A 1 102 ? 19.81538  -0.37572  -13.31485 1.000 32.91285 ? 100 GLN A CA  1 
ATOM   814  C  C   . GLN A 1 102 ? 21.15944  -1.04665  -13.09122 1.000 32.94763 ? 100 GLN A C   1 
ATOM   815  O  O   . GLN A 1 102 ? 21.24614  -2.27407  -13.16724 1.000 34.03543 ? 100 GLN A O   1 
ATOM   816  C  CB  . GLN A 1 102 ? 19.52821  -0.07660  -14.78331 1.000 37.53998 ? 100 GLN A CB  1 
ATOM   817  C  CG  . GLN A 1 102 ? 18.18236  0.58351   -14.79102 1.000 42.34554 ? 100 GLN A CG  1 
ATOM   818  C  CD  . GLN A 1 102 ? 17.02816  -0.43908  -14.74816 1.000 44.68046 ? 100 GLN A CD  1 
ATOM   819  O  OE1 . GLN A 1 102 ? 15.89014  -0.08965  -14.40333 1.000 49.54636 ? 100 GLN A OE1 1 
ATOM   820  N  NE2 . GLN A 1 102 ? 17.32263  -1.70455  -15.08560 1.000 49.84250 ? 100 GLN A NE2 1 
ATOM   821  N  N   . ALA A 1 103 ? 22.18934  -0.28810  -12.72480 1.000 30.22894 ? 101 ALA A N   1 
ATOM   822  C  CA  . ALA A 1 103 ? 23.47635  -0.90777  -12.42659 1.000 31.18276 ? 101 ALA A CA  1 
ATOM   823  C  C   . ALA A 1 103 ? 23.39340  -1.78760  -11.18288 1.000 34.28077 ? 101 ALA A C   1 
ATOM   824  O  O   . ALA A 1 103 ? 23.84484  -2.93903  -11.19791 1.000 33.71774 ? 101 ALA A O   1 
ATOM   825  C  CB  . ALA A 1 103 ? 24.55737  0.16065   -12.26017 1.000 31.27562 ? 101 ALA A CB  1 
ATOM   826  N  N   . VAL A 1 104 ? 22.78840  -1.28802  -10.09762 1.000 35.61611 ? 102 VAL A N   1 
ATOM   827  C  CA  . VAL A 1 104 ? 22.73553  -2.14477  -8.91228  1.000 33.39619 ? 102 VAL A CA  1 
ATOM   828  C  C   . VAL A 1 104 ? 21.70829  -3.27080  -9.08510  1.000 35.96378 ? 102 VAL A C   1 
ATOM   829  O  O   . VAL A 1 104 ? 21.89144  -4.37164  -8.55200  1.000 33.22237 ? 102 VAL A O   1 
ATOM   830  C  CB  . VAL A 1 104 ? 22.50007  -1.31678  -7.62833  1.000 34.62561 ? 102 VAL A CB  1 
ATOM   831  C  CG1 . VAL A 1 104 ? 21.06579  -0.80317  -7.52421  1.000 34.74453 ? 102 VAL A CG1 1 
ATOM   832  C  CG2 . VAL A 1 104 ? 22.83174  -2.17545  -6.42118  1.000 35.59905 ? 102 VAL A CG2 1 
ATOM   833  N  N   . ARG A 1 105 ? 20.63864  -3.03774  -9.84536  1.000 33.67341 ? 103 ARG A N   1 
ATOM   834  C  CA  . ARG A 1 105 ? 19.71240  -4.11246  -10.14585 1.000 35.14492 ? 103 ARG A CA  1 
ATOM   835  C  C   . ARG A 1 105 ? 20.35508  -5.19423  -11.01856 1.000 36.81619 ? 103 ARG A C   1 
ATOM   836  O  O   . ARG A 1 105 ? 19.89318  -6.34055  -11.00842 1.000 36.98832 ? 103 ARG A O   1 
ATOM   837  C  CB  . ARG A 1 105 ? 18.46904  -3.54780  -10.81506 1.000 34.80945 ? 103 ARG A CB  1 
ATOM   838  C  CG  . ARG A 1 105 ? 17.60023  -2.72543  -9.88636  1.000 34.49678 ? 103 ARG A CG  1 
ATOM   839  C  CD  . ARG A 1 105 ? 16.25839  -2.48365  -10.52201 1.000 35.83819 ? 103 ARG A CD  1 
ATOM   840  N  NE  . ARG A 1 105 ? 15.47233  -3.71400  -10.53774 1.000 34.15784 ? 103 ARG A NE  1 
ATOM   841  C  CZ  . ARG A 1 105 ? 14.23266  -3.79497  -11.00102 1.000 39.38913 ? 103 ARG A CZ  1 
ATOM   842  N  NH1 . ARG A 1 105 ? 13.61769  -2.73867  -11.52629 1.000 38.34095 ? 103 ARG A NH1 1 
ATOM   843  N  NH2 . ARG A 1 105 ? 13.58861  -4.95428  -10.92280 1.000 38.73684 ? 103 ARG A NH2 1 
ATOM   844  N  N   . LEU A 1 106 ? 21.42471  -4.86216  -11.75295 1.000 38.84836 ? 104 LEU A N   1 
ATOM   845  C  CA  . LEU A 1 106 ? 22.19575  -5.90369  -12.42887 1.000 33.62544 ? 104 LEU A CA  1 
ATOM   846  C  C   . LEU A 1 106 ? 22.77474  -6.88808  -11.41926 1.000 37.36767 ? 104 LEU A C   1 
ATOM   847  O  O   . LEU A 1 106 ? 22.82669  -8.09191  -11.67754 1.000 33.73916 ? 104 LEU A O   1 
ATOM   848  C  CB  . LEU A 1 106 ? 23.31357  -5.28742  -13.26472 1.000 34.85830 ? 104 LEU A CB  1 
ATOM   849  C  CG  . LEU A 1 106 ? 23.02388  -4.74602  -14.66875 1.000 35.60777 ? 104 LEU A CG  1 
ATOM   850  C  CD1 . LEU A 1 106 ? 24.30569  -4.21417  -15.27690 1.000 32.81410 ? 104 LEU A CD1 1 
ATOM   851  C  CD2 . LEU A 1 106 ? 22.39411  -5.78093  -15.59627 1.000 33.31336 ? 104 LEU A CD2 1 
ATOM   852  N  N   . LEU A 1 107 ? 23.21350  -6.40024  -10.25765 1.000 37.28991 ? 105 LEU A N   1 
ATOM   853  C  CA  . LEU A 1 107 ? 23.71626  -7.31703  -9.23166  1.000 37.11660 ? 105 LEU A CA  1 
ATOM   854  C  C   . LEU A 1 107 ? 22.58747  -8.13611  -8.62057  1.000 35.48271 ? 105 LEU A C   1 
ATOM   855  O  O   . LEU A 1 107 ? 22.72404  -9.34695  -8.40393  1.000 37.36872 ? 105 LEU A O   1 
ATOM   856  C  CB  . LEU A 1 107 ? 24.44188  -6.52224  -8.14887  1.000 37.81528 ? 105 LEU A CB  1 
ATOM   857  C  CG  . LEU A 1 107 ? 25.69274  -5.77176  -8.59400  1.000 37.82240 ? 105 LEU A CG  1 
ATOM   858  C  CD1 . LEU A 1 107 ? 26.39198  -5.16923  -7.38618  1.000 39.91011 ? 105 LEU A CD1 1 
ATOM   859  C  CD2 . LEU A 1 107 ? 26.61385  -6.71377  -9.34598  1.000 37.88424 ? 105 LEU A CD2 1 
ATOM   860  N  N   . THR A 1 108 ? 21.47282  -7.48640  -8.29774  1.000 38.70620 ? 106 THR A N   1 
ATOM   861  C  CA  . THR A 1 108 ? 20.32642  -8.21441  -7.77485  1.000 38.85837 ? 106 THR A CA  1 
ATOM   862  C  C   . THR A 1 108 ? 19.91862  -9.34822  -8.70981  1.000 37.99126 ? 106 THR A C   1 
ATOM   863  O  O   . THR A 1 108 ? 19.60185  -10.44980 -8.26257  1.000 32.94393 ? 106 THR A O   1 
ATOM   864  C  CB  . THR A 1 108 ? 19.15657  -7.26078  -7.56405  1.000 37.34055 ? 106 THR A CB  1 
ATOM   865  O  OG1 . THR A 1 108 ? 19.56510  -6.19067  -6.70033  1.000 42.25534 ? 106 THR A OG1 1 
ATOM   866  C  CG2 . THR A 1 108 ? 17.98382  -7.98178  -6.92930  1.000 35.93848 ? 106 THR A CG2 1 
ATOM   867  N  N   . ASP A 1 109 ? 19.88692  -9.08129  -10.00615 1.000 34.87370 ? 107 ASP A N   1 
ATOM   868  C  CA  . ASP A 1 109 ? 19.33857  -10.04854 -10.93983 1.000 36.81824 ? 107 ASP A CA  1 
ATOM   869  C  C   . ASP A 1 109 ? 20.35356  -11.12027 -11.32573 1.000 35.78006 ? 107 ASP A C   1 
ATOM   870  O  O   . ASP A 1 109 ? 19.95167  -12.21921 -11.69992 1.000 36.12976 ? 107 ASP A O   1 
ATOM   871  C  CB  . ASP A 1 109 ? 18.82627  -9.33932  -12.20212 1.000 35.15938 ? 107 ASP A CB  1 
ATOM   872  C  CG  . ASP A 1 109 ? 17.51654  -8.58492  -11.96349 1.000 40.36875 ? 107 ASP A CG  1 
ATOM   873  O  OD1 . ASP A 1 109 ? 16.80067  -8.86712  -10.98479 1.000 40.19540 ? 107 ASP A OD1 1 
ATOM   874  O  OD2 . ASP A 1 109 ? 17.22204  -7.65285  -12.73258 1.000 43.68021 ? 107 ASP A OD2 1 
ATOM   875  N  N   . HIS A 1 110 ? 21.65660  -10.82815 -11.28025 1.000 36.72882 ? 108 HIS A N   1 
ATOM   876  C  CA  . HIS A 1 110 ? 22.62558  -11.73014 -11.89119 1.000 39.80787 ? 108 HIS A CA  1 
ATOM   877  C  C   . HIS A 1 110 ? 23.82550  -12.09019 -11.03043 1.000 38.43796 ? 108 HIS A C   1 
ATOM   878  O  O   . HIS A 1 110 ? 24.49574  -13.07447 -11.34988 1.000 39.79930 ? 108 HIS A O   1 
ATOM   879  C  CB  . HIS A 1 110 ? 23.15135  -11.15096 -13.22095 1.000 36.75927 ? 108 HIS A CB  1 
ATOM   880  C  CG  . HIS A 1 110 ? 22.07158  -10.80125 -14.20280 1.000 38.61296 ? 108 HIS A CG  1 
ATOM   881  N  ND1 . HIS A 1 110 ? 21.30390  -11.75769 -14.83794 1.000 35.82113 ? 108 HIS A ND1 1 
ATOM   882  C  CD2 . HIS A 1 110 ? 21.62732  -9.59751  -14.65195 1.000 34.62593 ? 108 HIS A CD2 1 
ATOM   883  C  CE1 . HIS A 1 110 ? 20.44363  -11.15900 -15.64531 1.000 38.08134 ? 108 HIS A CE1 1 
ATOM   884  N  NE2 . HIS A 1 110 ? 20.61023  -9.84747  -15.54294 1.000 33.09015 ? 108 HIS A NE2 1 
ATOM   885  N  N   . LEU A 1 111 ? 24.14481  -11.34296 -9.99115  1.000 37.51626 ? 109 LEU A N   1 
ATOM   886  C  CA  . LEU A 1 111 ? 25.30568  -11.69815 -9.18276  1.000 38.59441 ? 109 LEU A CA  1 
ATOM   887  C  C   . LEU A 1 111 ? 24.94434  -12.85776 -8.25803  1.000 36.07014 ? 109 LEU A C   1 
ATOM   888  O  O   . LEU A 1 111 ? 24.03000  -12.71709 -7.43860  1.000 39.84709 ? 109 LEU A O   1 
ATOM   889  C  CB  . LEU A 1 111 ? 25.78627  -10.49535 -8.38056  1.000 37.58277 ? 109 LEU A CB  1 
ATOM   890  C  CG  . LEU A 1 111 ? 26.91433  -10.79805 -7.39876  1.000 38.86560 ? 109 LEU A CG  1 
ATOM   891  C  CD1 . LEU A 1 111 ? 28.19302  -11.01292 -8.15030  1.000 37.77955 ? 109 LEU A CD1 1 
ATOM   892  C  CD2 . LEU A 1 111 ? 27.10087  -9.68299  -6.41206  1.000 38.53089 ? 109 LEU A CD2 1 
ATOM   893  N  N   . PRO A 1 112 ? 25.60140  -14.01548 -8.36697  1.000 37.35265 ? 110 PRO A N   1 
ATOM   894  C  CA  . PRO A 1 112 ? 25.27400  -15.12491 -7.45242  1.000 37.63799 ? 110 PRO A CA  1 
ATOM   895  C  C   . PRO A 1 112 ? 25.68136  -14.79294 -6.02084  1.000 36.41154 ? 110 PRO A C   1 
ATOM   896  O  O   . PRO A 1 112 ? 26.82938  -14.43219 -5.75052  1.000 36.57797 ? 110 PRO A O   1 
ATOM   897  C  CB  . PRO A 1 112 ? 26.06856  -16.31601 -8.01006  1.000 38.06349 ? 110 PRO A CB  1 
ATOM   898  C  CG  . PRO A 1 112 ? 26.60715  -15.89402 -9.36199  1.000 37.60248 ? 110 PRO A CG  1 
ATOM   899  C  CD  . PRO A 1 112 ? 26.66904  -14.36536 -9.31604  1.000 36.97518 ? 110 PRO A CD  1 
ATOM   900  N  N   . GLN A 1 113 ? 24.72667  -14.91070 -5.10192  1.000 35.54272 ? 111 GLN A N   1 
ATOM   901  C  CA  . GLN A 1 113 ? 25.05285  -14.71714 -3.69346  1.000 40.09940 ? 111 GLN A CA  1 
ATOM   902  C  C   . GLN A 1 113 ? 26.27281  -15.54012 -3.29566  1.000 40.64567 ? 111 GLN A C   1 
ATOM   903  O  O   . GLN A 1 113 ? 27.16503  -15.05318 -2.59255  1.000 40.79596 ? 111 GLN A O   1 
ATOM   904  C  CB  . GLN A 1 113 ? 23.86411  -15.09638 -2.81707  1.000 42.92138 ? 111 GLN A CB  1 
ATOM   905  C  CG  . GLN A 1 113 ? 24.26803  -15.47219 -1.39947  1.000 44.71893 ? 111 GLN A CG  1 
ATOM   906  C  CD  . GLN A 1 113 ? 23.08224  -15.62771 -0.47693  1.000 43.86758 ? 111 GLN A CD  1 
ATOM   907  O  OE1 . GLN A 1 113 ? 22.10964  -16.30319 -0.81382  1.000 43.14303 ? 111 GLN A OE1 1 
ATOM   908  N  NE2 . GLN A 1 113 ? 23.14035  -14.97775 0.68191   1.000 42.10732 ? 111 GLN A NE2 1 
ATOM   909  N  N   . HIS A 1 114 ? 26.35141  -16.77844 -3.77376  1.000 40.84772 ? 112 HIS A N   1 
ATOM   910  C  CA  . HIS A 1 114 ? 27.49192  -17.61197 -3.41005  1.000 42.75518 ? 112 HIS A CA  1 
ATOM   911  C  C   . HIS A 1 114 ? 28.80256  -17.02261 -3.92087  1.000 43.77066 ? 112 HIS A C   1 
ATOM   912  O  O   . HIS A 1 114 ? 29.81804  -17.07238 -3.21919  1.000 42.51382 ? 112 HIS A O   1 
ATOM   913  C  CB  . HIS A 1 114 ? 27.30507  -19.03877 -3.91614  1.000 44.12156 ? 112 HIS A CB  1 
ATOM   914  C  CG  . HIS A 1 114 ? 28.34564  -19.97047 -3.39565  1.000 45.66024 ? 112 HIS A CG  1 
ATOM   915  N  ND1 . HIS A 1 114 ? 29.65780  -19.92113 -3.81553  1.000 45.93406 ? 112 HIS A ND1 1 
ATOM   916  C  CD2 . HIS A 1 114 ? 28.29360  -20.90994 -2.42203  1.000 44.60136 ? 112 HIS A CD2 1 
ATOM   917  C  CE1 . HIS A 1 114 ? 30.36008  -20.82518 -3.15626  1.000 47.77415 ? 112 HIS A CE1 1 
ATOM   918  N  NE2 . HIS A 1 114 ? 29.55844  -21.42832 -2.29630  1.000 47.18547 ? 112 HIS A NE2 1 
ATOM   919  N  N   . SER A 1 115 ? 28.80380  -16.45313 -5.13727  1.000 43.05811 ? 113 SER A N   1 
ATOM   920  C  CA  . SER A 1 115 ? 29.98973  -15.74806 -5.61756  1.000 42.06191 ? 113 SER A CA  1 
ATOM   921  C  C   . SER A 1 115 ? 30.30622  -14.55664 -4.73413  1.000 44.54302 ? 113 SER A C   1 
ATOM   922  O  O   . SER A 1 115 ? 31.47428  -14.30127 -4.40857  1.000 44.85780 ? 113 SER A O   1 
ATOM   923  C  CB  . SER A 1 115 ? 29.80207  -15.26459 -7.05884  1.000 40.74196 ? 113 SER A CB  1 
ATOM   924  O  OG  . SER A 1 115 ? 29.60540  -16.34691 -7.94664  1.000 40.24174 ? 113 SER A OG  1 
ATOM   925  N  N   . LEU A 1 116 ? 29.27827  -13.79028 -4.37235  1.000 42.01328 ? 114 LEU A N   1 
ATOM   926  C  CA  . LEU A 1 116 ? 29.50033  -12.59030 -3.58023  1.000 45.07240 ? 114 LEU A CA  1 
ATOM   927  C  C   . LEU A 1 116 ? 30.12323  -12.93866 -2.23748  1.000 44.91185 ? 114 LEU A C   1 
ATOM   928  O  O   . LEU A 1 116 ? 31.07012  -12.28107 -1.79126  1.000 45.08196 ? 114 LEU A O   1 
ATOM   929  C  CB  . LEU A 1 116 ? 28.17469  -11.84602 -3.39950  1.000 41.52406 ? 114 LEU A CB  1 
ATOM   930  C  CG  . LEU A 1 116 ? 28.10937  -10.53418 -2.61920  1.000 39.22835 ? 114 LEU A CG  1 
ATOM   931  C  CD1 . LEU A 1 116 ? 27.88345  -10.82361 -1.13114  1.000 42.46027 ? 114 LEU A CD1 1 
ATOM   932  C  CD2 . LEU A 1 116 ? 29.33849  -9.69816  -2.82515  1.000 40.67918 ? 114 LEU A CD2 1 
ATOM   933  N  N   . LEU A 1 117 ? 29.60751  -13.97452 -1.58270  1.000 45.09412 ? 115 LEU A N   1 
ATOM   934  C  CA  . LEU A 1 117 ? 30.14320  -14.34281 -0.27780  1.000 49.42252 ? 115 LEU A CA  1 
ATOM   935  C  C   . LEU A 1 117 ? 31.57889  -14.83597 -0.38736  1.000 47.53199 ? 115 LEU A C   1 
ATOM   936  O  O   . LEU A 1 117 ? 32.40141  -14.53641 0.48448   1.000 49.40365 ? 115 LEU A O   1 
ATOM   937  C  CB  . LEU A 1 117 ? 29.24596  -15.39131 0.38104   1.000 45.46659 ? 115 LEU A CB  1 
ATOM   938  C  CG  . LEU A 1 117 ? 27.90642  -14.73605 0.73532   1.000 49.39195 ? 115 LEU A CG  1 
ATOM   939  C  CD1 . LEU A 1 117 ? 26.86143  -15.74337 1.17276   1.000 48.01831 ? 115 LEU A CD1 1 
ATOM   940  C  CD2 . LEU A 1 117 ? 28.09718  -13.62287 1.78916   1.000 49.12084 ? 115 LEU A CD2 1 
ATOM   941  N  N   . MET A 1 118 ? 31.92461  -15.53565 -1.46694  1.000 45.96035 ? 116 MET A N   1 
ATOM   942  C  CA  . MET A 1 118 ? 33.30249  -15.99113 -1.57767  1.000 45.25727 ? 116 MET A CA  1 
ATOM   943  C  C   . MET A 1 118 ? 34.23971  -14.81771 -1.82095  1.000 49.45737 ? 116 MET A C   1 
ATOM   944  O  O   . MET A 1 118 ? 35.32868  -14.75198 -1.23438  1.000 47.78833 ? 116 MET A O   1 
ATOM   945  C  CB  . MET A 1 118 ? 33.43209  -17.03147 -2.68186  1.000 48.32687 ? 116 MET A CB  1 
ATOM   946  C  CG  . MET A 1 118 ? 32.55671  -18.22613 -2.39022  1.000 49.35236 ? 116 MET A CG  1 
ATOM   947  S  SD  . MET A 1 118 ? 33.26562  -19.29545 -1.13378  1.000 50.29308 ? 116 MET A SD  1 
ATOM   948  C  CE  . MET A 1 118 ? 31.91548  -19.26384 0.04396   1.000 47.73730 ? 116 MET A CE  1 
ATOM   949  N  N   . MET A 1 119 ? 33.82219  -13.86131 -2.66194  1.000 48.29376 ? 117 MET A N   1 
ATOM   950  C  CA  . MET A 1 119 ? 34.66059  -12.69371 -2.89421  1.000 48.67066 ? 117 MET A CA  1 
ATOM   951  C  C   . MET A 1 119 ? 34.76716  -11.86151 -1.62730  1.000 48.20727 ? 117 MET A C   1 
ATOM   952  O  O   . MET A 1 119 ? 35.84785  -11.35881 -1.29123  1.000 50.90222 ? 117 MET A O   1 
ATOM   953  C  CB  . MET A 1 119 ? 34.10924  -11.83891 -4.04312  1.000 44.51204 ? 117 MET A CB  1 
ATOM   954  C  CG  . MET A 1 119 ? 34.53900  -12.30603 -5.44073  1.000 42.94664 ? 117 MET A CG  1 
ATOM   955  S  SD  . MET A 1 119 ? 33.77628  -11.37838 -6.80037  1.000 43.98514 ? 117 MET A SD  1 
ATOM   956  C  CE  . MET A 1 119 ? 32.03010  -11.65014 -6.57555  1.000 41.61511 ? 117 MET A CE  1 
ATOM   957  N  N   . ARG A 1 120 ? 33.64932  -11.72128 -0.91128  1.000 47.09307 ? 118 ARG A N   1 
ATOM   958  C  CA  . ARG A 1 120 ? 33.59584  -10.87954 0.28136   1.000 51.95029 ? 118 ARG A CA  1 
ATOM   959  C  C   . ARG A 1 120 ? 34.50187  -11.39905 1.38427   1.000 53.90695 ? 118 ARG A C   1 
ATOM   960  O  O   . ARG A 1 120 ? 35.03431  -10.61093 2.17034   1.000 54.78306 ? 118 ARG A O   1 
ATOM   961  C  CB  . ARG A 1 120 ? 32.15482  -10.80440 0.78305   1.000 53.56897 ? 118 ARG A CB  1 
ATOM   962  C  CG  . ARG A 1 120 ? 31.88216  -9.76538  1.83239   1.000 53.44768 ? 118 ARG A CG  1 
ATOM   963  C  CD  . ARG A 1 120 ? 30.40929  -9.80875  2.19833   1.000 53.15216 ? 118 ARG A CD  1 
ATOM   964  N  NE  . ARG A 1 120 ? 30.07371  -8.82661  3.22137   1.000 53.87173 ? 118 ARG A NE  1 
ATOM   965  C  CZ  . ARG A 1 120 ? 29.91695  -9.12836  4.50341   1.000 57.13469 ? 118 ARG A CZ  1 
ATOM   966  N  NH1 . ARG A 1 120 ? 30.04396  -10.37230 4.94378   1.000 51.38232 ? 118 ARG A NH1 1 
ATOM   967  N  NH2 . ARG A 1 120 ? 29.62953  -8.16230  5.36389   1.000 58.35641 ? 118 ARG A NH2 1 
ATOM   968  N  N   . ASN A 1 121 ? 34.66954  -12.72070 1.47155   1.000 53.01008 ? 119 ASN A N   1 
ATOM   969  C  CA  . ASN A 1 121 ? 35.51419  -13.29778 2.51201   1.000 54.59799 ? 119 ASN A CA  1 
ATOM   970  C  C   . ASN A 1 121 ? 36.96697  -12.84909 2.37705   1.000 55.28481 ? 119 ASN A C   1 
ATOM   971  O  O   . ASN A 1 121 ? 37.68843  -12.78990 3.37740   1.000 57.77425 ? 119 ASN A O   1 
ATOM   972  C  CB  . ASN A 1 121 ? 35.39094  -14.82342 2.47887   1.000 54.63225 ? 119 ASN A CB  1 
ATOM   973  C  CG  . ASN A 1 121 ? 34.08883  -15.30709 3.10242   1.000 55.53064 ? 119 ASN A CG  1 
ATOM   974  O  OD1 . ASN A 1 121 ? 33.43608  -14.56912 3.84389   1.000 53.56152 ? 119 ASN A OD1 1 
ATOM   975  N  ND2 . ASN A 1 121 ? 33.70438  -16.54445 2.80702   1.000 55.41271 ? 119 ASN A ND2 1 
ATOM   976  N  N   . ALA A 1 122 ? 37.40261  -12.49055 1.16669   1.000 54.02353 ? 120 ALA A N   1 
ATOM   977  C  CA  . ALA A 1 122 ? 38.75833  -12.01035 0.93230   1.000 51.58400 ? 120 ALA A CA  1 
ATOM   978  C  C   . ALA A 1 122 ? 38.86398  -10.49260 0.79733   1.000 56.29015 ? 120 ALA A C   1 
ATOM   979  O  O   . ALA A 1 122 ? 39.98087  -9.97623  0.67911   1.000 55.83171 ? 120 ALA A O   1 
ATOM   980  C  CB  . ALA A 1 122 ? 39.33485  -12.65785 -0.32764  1.000 50.51187 ? 120 ALA A CB  1 
ATOM   981  N  N   . LEU A 1 123 ? 37.75039  -9.76452  0.79885   1.000 56.51315 ? 121 LEU A N   1 
ATOM   982  C  CA  . LEU A 1 123 ? 37.81720  -8.31962  0.64185   1.000 57.01708 ? 121 LEU A CA  1 
ATOM   983  C  C   . LEU A 1 123 ? 38.41574  -7.68835  1.89735   1.000 57.53023 ? 121 LEU A C   1 
ATOM   984  O  O   . LEU A 1 123 ? 38.40147  -8.29700  2.96946   1.000 59.76529 ? 121 LEU A O   1 
ATOM   985  C  CB  . LEU A 1 123 ? 36.42496  -7.75681  0.37970   1.000 54.99653 ? 121 LEU A CB  1 
ATOM   986  C  CG  . LEU A 1 123 ? 35.92085  -7.90306  -1.05224  1.000 50.23518 ? 121 LEU A CG  1 
ATOM   987  C  CD1 . LEU A 1 123 ? 34.50763  -7.37256  -1.12138  1.000 54.62212 ? 121 LEU A CD1 1 
ATOM   988  C  CD2 . LEU A 1 123 ? 36.82834  -7.15643  -2.01075  1.000 49.96141 ? 121 LEU A CD2 1 
ATOM   989  N  N   . PRO A 1 124 ? 38.95060  -6.47274  1.79368   1.000 60.50273 ? 122 PRO A N   1 
ATOM   990  C  CA  . PRO A 1 124 ? 39.48149  -5.80061  2.98571   1.000 60.12996 ? 122 PRO A CA  1 
ATOM   991  C  C   . PRO A 1 124 ? 38.38684  -5.46069  3.98611   1.000 62.24478 ? 122 PRO A C   1 
ATOM   992  O  O   . PRO A 1 124 ? 37.19126  -5.46764  3.68175   1.000 62.48070 ? 122 PRO A O   1 
ATOM   993  C  CB  . PRO A 1 124 ? 40.11690  -4.52988  2.41971   1.000 57.12260 ? 122 PRO A CB  1 
ATOM   994  C  CG  . PRO A 1 124 ? 40.40900  -4.85942  0.99999   1.000 55.42114 ? 122 PRO A CG  1 
ATOM   995  C  CD  . PRO A 1 124 ? 39.24366  -5.69965  0.57497   1.000 58.81364 ? 122 PRO A CD  1 
ATOM   996  N  N   . GLU A 1 125 ? 38.81914  -5.16335  5.20729   1.000 62.76982 ? 123 GLU A N   1 
ATOM   997  C  CA  . GLU A 1 125 ? 37.90149  -4.68959  6.23247   1.000 65.50478 ? 123 GLU A CA  1 
ATOM   998  C  C   . GLU A 1 125 ? 37.54244  -3.22470  5.98685   1.000 60.59533 ? 123 GLU A C   1 
ATOM   999  O  O   . GLU A 1 125 ? 38.33033  -2.45404  5.42735   1.000 62.68244 ? 123 GLU A O   1 
ATOM   1000 C  CB  . GLU A 1 125 ? 38.51301  -4.86253  7.62553   1.000 65.34421 ? 123 GLU A CB  1 
ATOM   1001 N  N   . ASP A 1 126 ? 36.33873  -2.84810  6.41901   1.000 61.37755 ? 124 ASP A N   1 
ATOM   1002 C  CA  . ASP A 1 126 ? 35.76576  -1.52294  6.16105   1.000 57.74057 ? 124 ASP A CA  1 
ATOM   1003 C  C   . ASP A 1 126 ? 35.93822  -1.13699  4.69662   1.000 56.75782 ? 124 ASP A C   1 
ATOM   1004 O  O   . ASP A 1 126 ? 36.40498  -0.04930  4.35469   1.000 56.34458 ? 124 ASP A O   1 
ATOM   1005 C  CB  . ASP A 1 126 ? 36.36195  -0.46167  7.08741   1.000 63.27985 ? 124 ASP A CB  1 
ATOM   1006 C  CG  . ASP A 1 126 ? 35.46030  0.77415   7.23755   1.000 61.61327 ? 124 ASP A CG  1 
ATOM   1007 O  OD1 . ASP A 1 126 ? 34.22102  0.63011   7.30862   1.000 61.33011 ? 124 ASP A OD1 1 
ATOM   1008 O  OD2 . ASP A 1 126 ? 35.99586  1.90441   7.26750   1.000 66.44031 ? 124 ASP A OD2 1 
ATOM   1009 N  N   . ALA A 1 127 ? 35.57782  -2.06876  3.82469   1.000 58.21352 ? 125 ALA A N   1 
ATOM   1010 C  CA  . ALA A 1 127 ? 35.46981  -1.82289  2.39130   1.000 54.66060 ? 125 ALA A CA  1 
ATOM   1011 C  C   . ALA A 1 127 ? 33.99242  -1.56064  2.13335   1.000 52.76525 ? 125 ALA A C   1 
ATOM   1012 O  O   . ALA A 1 127 ? 33.20262  -2.50133  2.00291   1.000 50.89422 ? 125 ALA A O   1 
ATOM   1013 C  CB  . ALA A 1 127 ? 35.99129  -3.00725  1.58689   1.000 56.38097 ? 125 ALA A CB  1 
ATOM   1014 N  N   . THR A 1 128 ? 33.62719  -0.27536  2.06832   1.000 49.61839 ? 126 THR A N   1 
ATOM   1015 C  CA  . THR A 1 128 ? 32.24392  0.17219   2.16518   1.000 50.61806 ? 126 THR A CA  1 
ATOM   1016 C  C   . THR A 1 128 ? 31.99081  1.32453   1.20650   1.000 48.84457 ? 126 THR A C   1 
ATOM   1017 O  O   . THR A 1 128 ? 32.86320  2.16825   0.98324   1.000 46.13734 ? 126 THR A O   1 
ATOM   1018 C  CB  . THR A 1 128 ? 31.89252  0.65700   3.58690   1.000 52.64167 ? 126 THR A CB  1 
ATOM   1019 O  OG1 . THR A 1 128 ? 30.66001  1.37498   3.54576   1.000 50.18198 ? 126 THR A OG1 1 
ATOM   1020 C  CG2 . THR A 1 128 ? 32.96779  1.61842   4.14847   1.000 51.05417 ? 126 THR A CG2 1 
ATOM   1021 N  N   . GLY A 1 129 ? 30.76068  1.38752   0.69224   1.000 46.89651 ? 127 GLY A N   1 
ATOM   1022 C  CA  . GLY A 1 129 ? 30.32293  2.51061   -0.13715  1.000 43.23797 ? 127 GLY A CA  1 
ATOM   1023 C  C   . GLY A 1 129 ? 30.05054  3.79568   0.61815   1.000 45.82722 ? 127 GLY A C   1 
ATOM   1024 O  O   . GLY A 1 129 ? 29.75661  4.81790   -0.01573  1.000 46.60003 ? 127 GLY A O   1 
ATOM   1025 N  N   . LEU A 1 130 ? 30.13089  3.77681   1.94889   1.000 46.21815 ? 128 LEU A N   1 
ATOM   1026 C  CA  . LEU A 1 130 ? 30.19614  5.03595   2.68528   1.000 45.09740 ? 128 LEU A CA  1 
ATOM   1027 C  C   . LEU A 1 130 ? 31.39730  5.86782   2.26367   1.000 48.28461 ? 128 LEU A C   1 
ATOM   1028 O  O   . LEU A 1 130 ? 31.43031  7.07837   2.52341   1.000 47.48722 ? 128 LEU A O   1 
ATOM   1029 C  CB  . LEU A 1 130 ? 30.24684  4.77297   4.19197   1.000 43.37688 ? 128 LEU A CB  1 
ATOM   1030 C  CG  . LEU A 1 130 ? 28.99112  4.11294   4.77081   1.000 52.95937 ? 128 LEU A CG  1 
ATOM   1031 C  CD1 . LEU A 1 130 ? 29.26384  3.49848   6.14320   1.000 54.13882 ? 128 LEU A CD1 1 
ATOM   1032 C  CD2 . LEU A 1 130 ? 27.83726  5.11966   4.84213   1.000 50.28611 ? 128 LEU A CD2 1 
ATOM   1033 N  N   . ASP A 1 131 ? 32.38750  5.24778   1.62691   1.000 48.20513 ? 129 ASP A N   1 
ATOM   1034 C  CA  . ASP A 1 131 ? 33.51753  5.96211   1.05763   1.000 47.46731 ? 129 ASP A CA  1 
ATOM   1035 C  C   . ASP A 1 131 ? 33.35593  6.21911   -0.43053  1.000 47.84990 ? 129 ASP A C   1 
ATOM   1036 O  O   . ASP A 1 131 ? 34.33861  6.55805   -1.09988  1.000 50.87345 ? 129 ASP A O   1 
ATOM   1037 C  CB  . ASP A 1 131 ? 34.80756  5.18244   1.31079   1.000 46.72896 ? 129 ASP A CB  1 
ATOM   1038 C  CG  . ASP A 1 131 ? 35.12872  5.06504   2.77604   1.000 52.75728 ? 129 ASP A CG  1 
ATOM   1039 O  OD1 . ASP A 1 131 ? 35.10981  6.10185   3.47582   1.000 55.22926 ? 129 ASP A OD1 1 
ATOM   1040 O  OD2 . ASP A 1 131 ? 35.38898  3.93745   3.23419   1.000 53.82904 ? 129 ASP A OD2 1 
ATOM   1041 N  N   . SER A 1 132 ? 32.16258  6.03911   -0.97445  1.000 48.58388 ? 130 SER A N   1 
ATOM   1042 C  CA  . SER A 1 132 ? 31.96192  6.31949   -2.39546  1.000 46.02213 ? 130 SER A CA  1 
ATOM   1043 C  C   . SER A 1 132 ? 32.08155  7.82173   -2.63207  1.000 46.17875 ? 130 SER A C   1 
ATOM   1044 O  O   . SER A 1 132 ? 31.42278  8.60559   -1.94201  1.000 44.31610 ? 130 SER A O   1 
ATOM   1045 C  CB  . SER A 1 132 ? 30.59073  5.82162   -2.85508  1.000 44.27939 ? 130 SER A CB  1 
ATOM   1046 O  OG  . SER A 1 132 ? 30.19600  6.47016   -4.05285  1.000 40.84772 ? 130 SER A OG  1 
ATOM   1047 N  N   . PRO A 1 133 ? 32.92337  8.26789   -3.56450  1.000 46.02806 ? 131 PRO A N   1 
ATOM   1048 C  CA  . PRO A 1 133 ? 32.92386  9.70552   -3.87846  1.000 46.06735 ? 131 PRO A CA  1 
ATOM   1049 C  C   . PRO A 1 133 ? 31.59877  10.15703  -4.45828  1.000 44.80850 ? 131 PRO A C   1 
ATOM   1050 O  O   . PRO A 1 133 ? 31.12198  11.24828  -4.13140  1.000 42.18163 ? 131 PRO A O   1 
ATOM   1051 C  CB  . PRO A 1 133 ? 34.07212  9.87352   -4.88345  1.000 45.94220 ? 131 PRO A CB  1 
ATOM   1052 C  CG  . PRO A 1 133 ? 34.64445  8.51938   -5.11845  1.000 46.93983 ? 131 PRO A CG  1 
ATOM   1053 C  CD  . PRO A 1 133 ? 34.02083  7.52661   -4.20761  1.000 48.16557 ? 131 PRO A CD  1 
ATOM   1054 N  N   . GLY A 1 134 ? 30.98234  9.33244   -5.30761  1.000 42.61393 ? 132 GLY A N   1 
ATOM   1055 C  CA  . GLY A 1 134 ? 29.68819  9.69615   -5.85482  1.000 39.15553 ? 132 GLY A CA  1 
ATOM   1056 C  C   . GLY A 1 134 ? 28.66648  9.92772   -4.76558  1.000 41.06434 ? 132 GLY A C   1 
ATOM   1057 O  O   . GLY A 1 134 ? 27.97286  10.94866  -4.74636  1.000 42.86807 ? 132 GLY A O   1 
ATOM   1058 N  N   . TYR A 1 135 ? 28.58904  9.00107   -3.81769  1.000 41.84664 ? 133 TYR A N   1 
ATOM   1059 C  CA  . TYR A 1 135 ? 27.58751  9.12015   -2.77156  1.000 45.23550 ? 133 TYR A CA  1 
ATOM   1060 C  C   . TYR A 1 135 ? 27.86650  10.30233  -1.84733  1.000 41.81909 ? 133 TYR A C   1 
ATOM   1061 O  O   . TYR A 1 135 ? 26.97645  11.12071  -1.59357  1.000 46.56769 ? 133 TYR A O   1 
ATOM   1062 C  CB  . TYR A 1 135 ? 27.49271  7.83248   -1.96924  1.000 42.28685 ? 133 TYR A CB  1 
ATOM   1063 C  CG  . TYR A 1 135 ? 26.31180  7.92779   -1.07281  1.000 45.83083 ? 133 TYR A CG  1 
ATOM   1064 C  CD1 . TYR A 1 135 ? 25.03316  8.05601   -1.60519  1.000 50.43726 ? 133 TYR A CD1 1 
ATOM   1065 C  CD2 . TYR A 1 135 ? 26.46545  7.99001   0.30304   1.000 47.25312 ? 133 TYR A CD2 1 
ATOM   1066 C  CE1 . TYR A 1 135 ? 23.92857  8.19403   -0.78257  1.000 51.13502 ? 133 TYR A CE1 1 
ATOM   1067 C  CE2 . TYR A 1 135 ? 25.37218  8.12681   1.13384   1.000 49.78547 ? 133 TYR A CE2 1 
ATOM   1068 C  CZ  . TYR A 1 135 ? 24.10697  8.22421   0.58648   1.000 53.85240 ? 133 TYR A CZ  1 
ATOM   1069 O  OH  . TYR A 1 135 ? 23.01311  8.35563   1.41562   1.000 62.28016 ? 133 TYR A OH  1 
ATOM   1070 N  N   . ARG A 1 136 ? 29.09127  10.40045  -1.32389  1.000 44.15320 ? 134 ARG A N   1 
ATOM   1071 C  CA  . ARG A 1 136 ? 29.42093  11.47230  -0.38333  1.000 45.32816 ? 134 ARG A CA  1 
ATOM   1072 C  C   . ARG A 1 136 ? 29.27687  12.84435  -1.02406  1.000 43.01923 ? 134 ARG A C   1 
ATOM   1073 O  O   . ARG A 1 136 ? 28.79659  13.78677  -0.39012  1.000 43.54070 ? 134 ARG A O   1 
ATOM   1074 C  CB  . ARG A 1 136 ? 30.84523  11.29930  0.14193   1.000 47.79707 ? 134 ARG A CB  1 
ATOM   1075 C  CG  . ARG A 1 136 ? 31.03025  10.16962  1.14956   1.000 44.97300 ? 134 ARG A CG  1 
ATOM   1076 C  CD  . ARG A 1 136 ? 32.50908  9.81891   1.23958   1.000 48.68057 ? 134 ARG A CD  1 
ATOM   1077 N  NE  . ARG A 1 136 ? 33.22323  10.72894  2.13063   1.000 56.83641 ? 134 ARG A NE  1 
ATOM   1078 C  CZ  . ARG A 1 136 ? 33.39855  10.52508  3.42942   1.000 57.37634 ? 134 ARG A CZ  1 
ATOM   1079 N  NH1 . ARG A 1 136 ? 32.92903  9.44294   4.03246   1.000 59.84829 ? 134 ARG A NH1 1 
ATOM   1080 N  NH2 . ARG A 1 136 ? 34.07569  11.41992  4.13782   1.000 60.67013 ? 134 ARG A NH2 1 
ATOM   1081 N  N   . ASN A 1 137 ? 29.70850  12.99190  -2.27146  1.000 41.87462 ? 135 ASN A N   1 
ATOM   1082 C  CA  . ASN A 1 137 ? 29.65069  14.32350  -2.86733  1.000 40.87895 ? 135 ASN A CA  1 
ATOM   1083 C  C   . ASN A 1 137 ? 28.23012  14.67888  -3.26363  1.000 42.52547 ? 135 ASN A C   1 
ATOM   1084 O  O   . ASN A 1 137 ? 27.84889  15.85363  -3.21385  1.000 44.28465 ? 135 ASN A O   1 
ATOM   1085 C  CB  . ASN A 1 137 ? 30.59948  14.42391  -4.05773  1.000 41.13216 ? 135 ASN A CB  1 
ATOM   1086 C  CG  . ASN A 1 137 ? 32.06385  14.41943  -3.63556  1.000 46.05547 ? 135 ASN A CG  1 
ATOM   1087 O  OD1 . ASN A 1 137 ? 32.46415  15.16614  -2.73781  1.000 46.53778 ? 135 ASN A OD1 1 
ATOM   1088 N  ND2 . ASN A 1 137 ? 32.86223  13.56552  -4.26508  1.000 44.73697 ? 135 ASN A ND2 1 
ATOM   1089 N  N   . LEU A 1 138 ? 27.42398  13.68440  -3.62487  1.000 39.90507 ? 136 LEU A N   1 
ATOM   1090 C  CA  . LEU A 1 138 ? 26.01142  13.94976  -3.84846  1.000 41.15060 ? 136 LEU A CA  1 
ATOM   1091 C  C   . LEU A 1 138 ? 25.34705  14.43965  -2.56474  1.000 43.93403 ? 136 LEU A C   1 
ATOM   1092 O  O   . LEU A 1 138 ? 24.62139  15.44047  -2.56930  1.000 44.98535 ? 136 LEU A O   1 
ATOM   1093 C  CB  . LEU A 1 138 ? 25.32267  12.68994  -4.36999  1.000 38.98121 ? 136 LEU A CB  1 
ATOM   1094 C  CG  . LEU A 1 138 ? 23.79578  12.73822  -4.41678  1.000 41.08284 ? 136 LEU A CG  1 
ATOM   1095 C  CD1 . LEU A 1 138 ? 23.33852  13.81693  -5.42598  1.000 41.47439 ? 136 LEU A CD1 1 
ATOM   1096 C  CD2 . LEU A 1 138 ? 23.22323  11.35919  -4.76391  1.000 41.64305 ? 136 LEU A CD2 1 
ATOM   1097 N  N   . ARG A 1 139 ? 25.59163  13.74192  -1.45257  1.000 43.16668 ? 137 ARG A N   1 
ATOM   1098 C  CA  . ARG A 1 139 ? 25.04633  14.16182  -0.16730  1.000 42.13845 ? 137 ARG A CA  1 
ATOM   1099 C  C   . ARG A 1 139 ? 25.55802  15.54600  0.21129   1.000 47.31460 ? 137 ARG A C   1 
ATOM   1100 O  O   . ARG A 1 139 ? 24.80420  16.36936  0.73406   1.000 46.86442 ? 137 ARG A O   1 
ATOM   1101 C  CB  . ARG A 1 139 ? 25.40311  13.12422  0.90318   1.000 46.12378 ? 137 ARG A CB  1 
ATOM   1102 C  CG  . ARG A 1 139 ? 24.93982  13.44477  2.32130   1.000 53.31395 ? 137 ARG A CG  1 
ATOM   1103 C  CD  . ARG A 1 139 ? 24.05271  12.34294  2.90167   1.000 56.94429 ? 137 ARG A CD  1 
ATOM   1104 N  NE  . ARG A 1 139 ? 22.81278  12.14787  2.14725   1.000 61.84276 ? 137 ARG A NE  1 
ATOM   1105 C  CZ  . ARG A 1 139 ? 21.62274  12.60784  2.52033   1.000 58.07290 ? 137 ARG A CZ  1 
ATOM   1106 N  NH1 . ARG A 1 139 ? 21.46564  13.29556  3.64199   1.000 57.15905 ? 137 ARG A NH1 1 
ATOM   1107 N  NH2 . ARG A 1 139 ? 20.56181  12.36939  1.75220   1.000 53.87981 ? 137 ARG A NH2 1 
ATOM   1108 N  N   . ARG A 1 140 ? 26.82613  15.83255  -0.08989  1.000 45.88905 ? 138 ARG A N   1 
ATOM   1109 C  CA  . ARG A 1 140 ? 27.40234  17.14263  0.19698   1.000 43.43683 ? 138 ARG A CA  1 
ATOM   1110 C  C   . ARG A 1 140 ? 26.70521  18.25303  -0.59347  1.000 46.07854 ? 138 ARG A C   1 
ATOM   1111 O  O   . ARG A 1 140 ? 26.33550  19.29274  -0.03384  1.000 44.53685 ? 138 ARG A O   1 
ATOM   1112 C  CB  . ARG A 1 140 ? 28.90017  17.11577  -0.12782  1.000 46.74991 ? 138 ARG A CB  1 
ATOM   1113 C  CG  . ARG A 1 140 ? 29.76526  18.10542  0.65857   1.000 52.47359 ? 138 ARG A CG  1 
ATOM   1114 C  CD  . ARG A 1 140 ? 31.17118  18.25623  0.03043   1.000 53.12471 ? 138 ARG A CD  1 
ATOM   1115 N  NE  . ARG A 1 140 ? 31.80643  16.98652  -0.32037  1.000 50.83329 ? 138 ARG A NE  1 
ATOM   1116 C  CZ  . ARG A 1 140 ? 31.98262  15.95651  0.50156   1.000 52.68137 ? 138 ARG A CZ  1 
ATOM   1117 N  NH1 . ARG A 1 140 ? 31.63911  16.01834  1.77886   1.000 55.18570 ? 138 ARG A NH1 1 
ATOM   1118 N  NH2 . ARG A 1 140 ? 32.52879  14.83571  0.03152   1.000 50.98493 ? 138 ARG A NH2 1 
ATOM   1119 N  N   . VAL A 1 141 ? 26.52737  18.05270  -1.90202  1.000 40.74766 ? 139 VAL A N   1 
ATOM   1120 C  CA  . VAL A 1 141 ? 26.01595  19.10605  -2.77431  1.000 40.57213 ? 139 VAL A CA  1 
ATOM   1121 C  C   . VAL A 1 141 ? 24.51321  19.31277  -2.61937  1.000 41.83012 ? 139 VAL A C   1 
ATOM   1122 O  O   . VAL A 1 141 ? 23.99847  20.35919  -3.02217  1.000 41.71981 ? 139 VAL A O   1 
ATOM   1123 C  CB  . VAL A 1 141 ? 26.35634  18.79420  -4.24756  1.000 40.63613 ? 139 VAL A CB  1 
ATOM   1124 C  CG1 . VAL A 1 141 ? 25.37211  17.78927  -4.83466  1.000 39.57744 ? 139 VAL A CG1 1 
ATOM   1125 C  CG2 . VAL A 1 141 ? 26.40909  20.05674  -5.09183  1.000 41.00411 ? 139 VAL A CG2 1 
ATOM   1126 N  N   . ALA A 1 142 ? 23.79405  18.35272  -2.04031  1.000 41.31237 ? 140 ALA A N   1 
ATOM   1127 C  CA  . ALA A 1 142 ? 22.33799  18.45395  -1.95846  1.000 43.65027 ? 140 ALA A CA  1 
ATOM   1128 C  C   . ALA A 1 142 ? 21.88826  19.63813  -1.11080  1.000 43.44117 ? 140 ALA A C   1 
ATOM   1129 O  O   . ALA A 1 142 ? 20.81606  20.20969  -1.36217  1.000 37.46736 ? 140 ALA A O   1 
ATOM   1130 C  CB  . ALA A 1 142 ? 21.75416  17.15735  -1.39752  1.000 37.46622 ? 140 ALA A CB  1 
ATOM   1131 N  N   . ARG A 1 143 ? 22.68141  20.01193  -0.09867  1.000 44.47312 ? 141 ARG A N   1 
ATOM   1132 C  CA  . ARG A 1 143 ? 22.33408  21.19432  0.69195   1.000 46.20458 ? 141 ARG A CA  1 
ATOM   1133 C  C   . ARG A 1 143 ? 22.47953  22.48102  -0.11622  1.000 43.12476 ? 141 ARG A C   1 
ATOM   1134 O  O   . ARG A 1 143 ? 21.51080  23.26231  -0.17502  1.000 43.73988 ? 141 ARG A O   1 
ATOM   1135 C  CB  . ARG A 1 143 ? 23.16602  21.22494  1.98066   1.000 47.36683 ? 141 ARG A CB  1 
ATOM   1136 C  CG  . ARG A 1 143 ? 22.82316  20.15378  2.97892   1.000 47.21970 ? 141 ARG A CG  1 
ATOM   1137 C  CD  . ARG A 1 143 ? 21.46757  20.42685  3.61233   1.000 54.03644 ? 141 ARG A CD  1 
ATOM   1138 N  NE  . ARG A 1 143 ? 20.38151  19.77236  2.88320   1.000 58.05663 ? 141 ARG A NE  1 
ATOM   1139 C  CZ  . ARG A 1 143 ? 19.19697  20.32451  2.64327   1.000 55.06320 ? 141 ARG A CZ  1 
ATOM   1140 N  NH1 . ARG A 1 143 ? 18.91015  21.54884  3.05196   1.000 52.80237 ? 141 ARG A NH1 1 
ATOM   1141 N  NH2 . ARG A 1 143 ? 18.27282  19.62370  1.98722   1.000 51.65121 ? 141 ARG A NH2 1 
ATOM   1142 N  N   . PRO A 1 144 ? 23.62523  22.78471  -0.73784  1.000 39.45384 ? 142 PRO A N   1 
ATOM   1143 C  CA  . PRO A 1 144 ? 23.66437  23.98621  -1.59637  1.000 43.07943 ? 142 PRO A CA  1 
ATOM   1144 C  C   . PRO A 1 144 ? 22.59799  23.97799  -2.67503  1.000 40.18929 ? 142 PRO A C   1 
ATOM   1145 O  O   . PRO A 1 144 ? 22.13687  25.04816  -3.08913  1.000 38.53859 ? 142 PRO A O   1 
ATOM   1146 C  CB  . PRO A 1 144 ? 25.06870  23.95880  -2.21183  1.000 43.21129 ? 142 PRO A CB  1 
ATOM   1147 C  CG  . PRO A 1 144 ? 25.84971  23.00040  -1.41138  1.000 44.25461 ? 142 PRO A CG  1 
ATOM   1148 C  CD  . PRO A 1 144 ? 24.94489  22.14106  -0.60669  1.000 43.14664 ? 142 PRO A CD  1 
ATOM   1149 N  N   . VAL A 1 145 ? 22.18253  22.79710  -3.14121  1.000 37.19304 ? 143 VAL A N   1 
ATOM   1150 C  CA  . VAL A 1 145 ? 21.16639  22.75062  -4.18317  1.000 36.31498 ? 143 VAL A CA  1 
ATOM   1151 C  C   . VAL A 1 145 ? 19.81765  23.16591  -3.62682  1.000 36.41241 ? 143 VAL A C   1 
ATOM   1152 O  O   . VAL A 1 145 ? 19.10960  23.97837  -4.22760  1.000 32.92994 ? 143 VAL A O   1 
ATOM   1153 C  CB  . VAL A 1 145 ? 21.08352  21.35180  -4.81987  1.000 38.06723 ? 143 VAL A CB  1 
ATOM   1154 C  CG1 . VAL A 1 145 ? 19.85140  21.29206  -5.69829  1.000 33.11194 ? 143 VAL A CG1 1 
ATOM   1155 C  CG2 . VAL A 1 145 ? 22.34469  21.03889  -5.61098  1.000 37.34357 ? 143 VAL A CG2 1 
ATOM   1156 N  N   . TRP A 1 146 ? 19.41129  22.58521  -2.49455  1.000 38.32390 ? 144 TRP A N   1 
ATOM   1157 C  CA  . TRP A 1 146 ? 18.14833  23.02603  -1.91561  1.000 38.91177 ? 144 TRP A CA  1 
ATOM   1158 C  C   . TRP A 1 146 ? 18.19178  24.52029  -1.62648  1.000 36.72418 ? 144 TRP A C   1 
ATOM   1159 O  O   . TRP A 1 146 ? 17.22797  25.24690  -1.90506  1.000 35.46903 ? 144 TRP A O   1 
ATOM   1160 C  CB  . TRP A 1 146 ? 17.78930  22.25376  -0.63349  1.000 39.83495 ? 144 TRP A CB  1 
ATOM   1161 C  CG  . TRP A 1 146 ? 16.56163  22.88788  -0.09088  1.000 40.62628 ? 144 TRP A CG  1 
ATOM   1162 C  CD1 . TRP A 1 146 ? 16.46014  23.73054  0.99285   1.000 41.60883 ? 144 TRP A CD1 1 
ATOM   1163 C  CD2 . TRP A 1 146 ? 15.26738  22.86434  -0.69970  1.000 41.74251 ? 144 TRP A CD2 1 
ATOM   1164 N  NE1 . TRP A 1 146 ? 15.16348  24.18397  1.11621   1.000 35.97254 ? 144 TRP A NE1 1 
ATOM   1165 C  CE2 . TRP A 1 146 ? 14.41671  23.67967  0.08577   1.000 38.90773 ? 144 TRP A CE2 1 
ATOM   1166 C  CE3 . TRP A 1 146 ? 14.73951  22.21778  -1.82394  1.000 38.99008 ? 144 TRP A CE3 1 
ATOM   1167 C  CZ2 . TRP A 1 146 ? 13.07104  23.85856  -0.21305  1.000 41.00314 ? 144 TRP A CZ2 1 
ATOM   1168 C  CZ3 . TRP A 1 146 ? 13.39600  22.40927  -2.12458  1.000 43.01281 ? 144 TRP A CZ3 1 
ATOM   1169 C  CH2 . TRP A 1 146 ? 12.58017  23.22063  -1.32075  1.000 38.78293 ? 144 TRP A CH2 1 
ATOM   1170 N  N   . LYS A 1 147 ? 19.32746  25.00222  -1.12274  1.000 38.33688 ? 145 LYS A N   1 
ATOM   1171 C  CA  . LYS A 1 147 ? 19.45909  26.42211  -0.78168  1.000 37.92824 ? 145 LYS A CA  1 
ATOM   1172 C  C   . LYS A 1 147 ? 19.26548  27.31484  -2.00784  1.000 41.06884 ? 145 LYS A C   1 
ATOM   1173 O  O   . LYS A 1 147 ? 18.56851  28.33669  -1.93931  1.000 38.24221 ? 145 LYS A O   1 
ATOM   1174 C  CB  . LYS A 1 147 ? 20.82751  26.66599  -0.13819  1.000 40.04285 ? 145 LYS A CB  1 
ATOM   1175 C  CG  . LYS A 1 147 ? 20.99159  28.05494  0.49144   1.000 50.04109 ? 145 LYS A CG  1 
ATOM   1176 C  CD  . LYS A 1 147 ? 22.22584  28.13449  1.40049   1.000 55.10450 ? 145 LYS A CD  1 
ATOM   1177 C  CE  . LYS A 1 147 ? 21.89886  27.72774  2.84351   1.000 53.40439 ? 145 LYS A CE  1 
ATOM   1178 N  NZ  . LYS A 1 147 ? 22.53724  28.63548  3.84697   1.000 57.98910 ? 145 LYS A NZ  1 
ATOM   1179 N  N   . ALA A 1 148 ? 19.85999  26.94002  -3.14974  1.000 39.78702 ? 146 ALA A N   1 
ATOM   1180 C  CA  . ALA A 1 148 ? 19.68739  27.75353  -4.34984  1.000 35.20652 ? 146 ALA A CA  1 
ATOM   1181 C  C   . ALA A 1 148 ? 18.22611  27.77548  -4.79267  1.000 36.85875 ? 146 ALA A C   1 
ATOM   1182 O  O   . ALA A 1 148 ? 17.72527  28.82009  -5.23504  1.000 35.06587 ? 146 ALA A O   1 
ATOM   1183 C  CB  . ALA A 1 148 ? 20.59093  27.24297  -5.47802  1.000 38.49982 ? 146 ALA A CB  1 
ATOM   1184 N  N   . TYR A 1 149 ? 17.51561  26.63671  -4.68684  1.000 35.34680 ? 147 TYR A N   1 
ATOM   1185 C  CA  . TYR A 1 149 ? 16.10624  26.63742  -5.09556  1.000 33.21740 ? 147 TYR A CA  1 
ATOM   1186 C  C   . TYR A 1 149 ? 15.25644  27.48100  -4.14165  1.000 36.05647 ? 147 TYR A C   1 
ATOM   1187 O  O   . TYR A 1 149 ? 14.42049  28.29121  -4.57309  1.000 35.67689 ? 147 TYR A O   1 
ATOM   1188 C  CB  . TYR A 1 149 ? 15.54899  25.20852  -5.17684  1.000 32.72446 ? 147 TYR A CB  1 
ATOM   1189 C  CG  . TYR A 1 149 ? 14.09568  25.22854  -5.58188  1.000 30.71329 ? 147 TYR A CG  1 
ATOM   1190 C  CD1 . TYR A 1 149 ? 13.72543  25.61702  -6.86966  1.000 31.97018 ? 147 TYR A CD1 1 
ATOM   1191 C  CD2 . TYR A 1 149 ? 13.09173  24.91535  -4.67787  1.000 29.91392 ? 147 TYR A CD2 1 
ATOM   1192 C  CE1 . TYR A 1 149 ? 12.38897  25.68020  -7.25205  1.000 27.80710 ? 147 TYR A CE1 1 
ATOM   1193 C  CE2 . TYR A 1 149 ? 11.74510  24.97200  -5.04773  1.000 29.53393 ? 147 TYR A CE2 1 
ATOM   1194 C  CZ  . TYR A 1 149 ? 11.41096  25.37151  -6.34197  1.000 31.76339 ? 147 TYR A CZ  1 
ATOM   1195 O  OH  . TYR A 1 149 ? 10.09691  25.44169  -6.74962  1.000 32.24985 ? 147 TYR A OH  1 
ATOM   1196 N  N   . GLU A 1 150 ? 15.44564  27.28330  -2.83795  1.000 36.75490 ? 148 GLU A N   1 
ATOM   1197 C  CA  . GLU A 1 150 ? 14.71102  28.05494  -1.83758  1.000 35.58778 ? 148 GLU A CA  1 
ATOM   1198 C  C   . GLU A 1 150 ? 14.87297  29.55026  -2.06113  1.000 38.44854 ? 148 GLU A C   1 
ATOM   1199 O  O   . GLU A 1 150 ? 13.88130  30.29409  -2.08235  1.000 37.77767 ? 148 GLU A O   1 
ATOM   1200 C  CB  . GLU A 1 150 ? 15.19104  27.64441  -0.44697  1.000 40.16642 ? 148 GLU A CB  1 
ATOM   1201 C  CG  . GLU A 1 150 ? 14.65343  28.43987  0.71648   1.000 42.59883 ? 148 GLU A CG  1 
ATOM   1202 C  CD  . GLU A 1 150 ? 14.93719  27.71063  2.01418   1.000 49.58108 ? 148 GLU A CD  1 
ATOM   1203 O  OE1 . GLU A 1 150 ? 16.04576  27.87159  2.57040   1.000 56.47972 ? 148 GLU A OE1 1 
ATOM   1204 O  OE2 . GLU A 1 150 ? 14.07234  26.92189  2.43964   1.000 53.90054 ? 148 GLU A OE2 1 
ATOM   1205 N  N   . GLN A 1 151 ? 16.11379  30.01514  -2.24938  1.000 35.71591 ? 149 GLN A N   1 
ATOM   1206 C  CA  . GLN A 1 151 ? 16.30855  31.46106  -2.41208  1.000 40.68461 ? 149 GLN A CA  1 
ATOM   1207 C  C   . GLN A 1 151 ? 15.74330  31.97444  -3.72798  1.000 38.77451 ? 149 GLN A C   1 
ATOM   1208 O  O   . GLN A 1 151 ? 15.35098  33.13491  -3.81436  1.000 36.09925 ? 149 GLN A O   1 
ATOM   1209 C  CB  . GLN A 1 151 ? 17.78781  31.82221  -2.30866  1.000 37.58136 ? 149 GLN A CB  1 
ATOM   1210 C  CG  . GLN A 1 151 ? 18.33630  31.55370  -0.93767  1.000 44.36907 ? 149 GLN A CG  1 
ATOM   1211 C  CD  . GLN A 1 151 ? 19.82380  31.51460  -0.94040  1.000 47.56698 ? 149 GLN A CD  1 
ATOM   1212 O  OE1 . GLN A 1 151 ? 20.44969  31.95132  -1.89103  1.000 52.01814 ? 149 GLN A OE1 1 
ATOM   1213 N  NE2 . GLN A 1 151 ? 20.41024  31.01588  0.13627   1.000 50.90037 ? 149 GLN A NE2 1 
ATOM   1214 N  N   . ALA A 1 152 ? 15.70542  31.14774  -4.77273  1.000 35.37723 ? 150 ALA A N   1 
ATOM   1215 C  CA  . ALA A 1 152 ? 15.05924  31.60395  -5.99823  1.000 35.19909 ? 150 ALA A CA  1 
ATOM   1216 C  C   . ALA A 1 152 ? 13.55884  31.76307  -5.78397  1.000 34.95359 ? 150 ALA A C   1 
ATOM   1217 O  O   . ALA A 1 152 ? 12.94825  32.73936  -6.24380  1.000 36.52523 ? 150 ALA A O   1 
ATOM   1218 C  CB  . ALA A 1 152 ? 15.35675  30.63154  -7.14305  1.000 37.00909 ? 150 ALA A CB  1 
ATOM   1219 N  N   . VAL A 1 153 ? 12.95827  30.83836  -5.04440  1.000 33.80580 ? 151 VAL A N   1 
ATOM   1220 C  CA  . VAL A 1 153 ? 11.54480  30.95849  -4.70510  1.000 34.99667 ? 151 VAL A CA  1 
ATOM   1221 C  C   . VAL A 1 153 ? 11.30441  32.21198  -3.88251  1.000 35.50807 ? 151 VAL A C   1 
ATOM   1222 O  O   . VAL A 1 153 ? 10.28648  32.90207  -4.04609  1.000 36.16262 ? 151 VAL A O   1 
ATOM   1223 C  CB  . VAL A 1 153 ? 11.08452  29.69632  -3.95836  1.000 32.55450 ? 151 VAL A CB  1 
ATOM   1224 C  CG1 . VAL A 1 153 ? 9.68676   29.89014  -3.36235  1.000 32.91874 ? 151 VAL A CG1 1 
ATOM   1225 C  CG2 . VAL A 1 153 ? 11.13667  28.48392  -4.93097  1.000 31.77905 ? 151 VAL A CG2 1 
ATOM   1226 N  N   . GLU A 1 154 ? 12.23976  32.52438  -2.99042  1.000 35.48991 ? 152 GLU A N   1 
ATOM   1227 C  CA  . GLU A 1 154 ? 12.05648  33.65592  -2.08618  1.000 39.54714 ? 152 GLU A CA  1 
ATOM   1228 C  C   . GLU A 1 154 ? 12.17392  34.97444  -2.84586  1.000 36.69725 ? 152 GLU A C   1 
ATOM   1229 O  O   . GLU A 1 154 ? 11.34543  35.88432  -2.68080  1.000 36.70994 ? 152 GLU A O   1 
ATOM   1230 C  CB  . GLU A 1 154 ? 13.09181  33.56561  -0.96912  1.000 40.34928 ? 152 GLU A CB  1 
ATOM   1231 C  CG  . GLU A 1 154 ? 12.56963  32.92992  0.31075   1.000 41.76374 ? 152 GLU A CG  1 
ATOM   1232 C  CD  . GLU A 1 154 ? 13.69385  32.42671  1.21632   1.000 43.50883 ? 152 GLU A CD  1 
ATOM   1233 O  OE1 . GLU A 1 154 ? 14.82916  32.96192  1.12126   1.000 48.61642 ? 152 GLU A OE1 1 
ATOM   1234 O  OE2 . GLU A 1 154 ? 13.41705  31.57802  2.09125   1.000 46.80625 ? 152 GLU A OE2 1 
ATOM   1235 N  N   . ARG A 1 155 ? 13.20069  35.09675  -3.69422  1.000 34.91525 ? 153 ARG A N   1 
ATOM   1236 C  CA  . ARG A 1 155 ? 13.30944  36.26940  -4.55679  1.000 35.02648 ? 153 ARG A CA  1 
ATOM   1237 C  C   . ARG A 1 155 ? 12.06427  36.45390  -5.41009  1.000 36.51988 ? 153 ARG A C   1 
ATOM   1238 O  O   . ARG A 1 155 ? 11.68502  37.58628  -5.71037  1.000 35.59065 ? 153 ARG A O   1 
ATOM   1239 C  CB  . ARG A 1 155 ? 14.54038  36.16410  -5.44915  1.000 36.34610 ? 153 ARG A CB  1 
ATOM   1240 C  CG  . ARG A 1 155 ? 15.86322  36.14535  -4.69178  1.000 37.22161 ? 153 ARG A CG  1 
ATOM   1241 C  CD  . ARG A 1 155 ? 17.02146  36.41262  -5.64591  1.000 38.10559 ? 153 ARG A CD  1 
ATOM   1242 N  NE  . ARG A 1 155 ? 17.17096  35.36785  -6.66356  1.000 37.00300 ? 153 ARG A NE  1 
ATOM   1243 C  CZ  . ARG A 1 155 ? 17.78099  34.20218  -6.47371  1.000 39.44602 ? 153 ARG A CZ  1 
ATOM   1244 N  NH1 . ARG A 1 155 ? 18.26301  33.85428  -5.28890  1.000 38.31589 ? 153 ARG A NH1 1 
ATOM   1245 N  NH2 . ARG A 1 155 ? 17.91265  33.35669  -7.50338  1.000 37.34915 ? 153 ARG A NH2 1 
ATOM   1246 N  N   . ALA A 1 156 ? 11.40382  35.37197  -5.80149  1.000 36.61749 ? 154 ALA A N   1 
ATOM   1247 C  CA  . ALA A 1 156 ? 10.16485  35.50609  -6.55967  1.000 35.09363 ? 154 ALA A CA  1 
ATOM   1248 C  C   . ALA A 1 156 ? 8.96771   35.87561  -5.69203  1.000 35.86304 ? 154 ALA A C   1 
ATOM   1249 O  O   . ALA A 1 156 ? 7.89119   36.15708  -6.23674  1.000 36.93695 ? 154 ALA A O   1 
ATOM   1250 C  CB  . ALA A 1 156 ? 9.87366   34.20416  -7.32320  1.000 34.51785 ? 154 ALA A CB  1 
ATOM   1251 N  N   . GLY A 1 157 ? 9.11782   35.87994  -4.36856  1.000 34.94341 ? 155 GLY A N   1 
ATOM   1252 C  CA  . GLY A 1 157 ? 8.00389   36.22054  -3.49846  1.000 37.66650 ? 155 GLY A CA  1 
ATOM   1253 C  C   . GLY A 1 157 ? 6.85151   35.24340  -3.53933  1.000 37.26685 ? 155 GLY A C   1 
ATOM   1254 O  O   . GLY A 1 157 ? 5.69562   35.63109  -3.29901  1.000 32.10627 ? 155 GLY A O   1 
ATOM   1255 N  N   . LEU A 1 158 ? 7.13777   33.97775  -3.83978  1.000 36.11862 ? 156 LEU A N   1 
ATOM   1256 C  CA  . LEU A 1 158 ? 6.14436   32.92354  -3.96999  1.000 37.68505 ? 156 LEU A CA  1 
ATOM   1257 C  C   . LEU A 1 158 ? 6.14497   32.04563  -2.72585  1.000 35.09028 ? 156 LEU A C   1 
ATOM   1258 O  O   . LEU A 1 158 ? 7.16636   31.90170  -2.05058  1.000 34.49686 ? 156 LEU A O   1 
ATOM   1259 C  CB  . LEU A 1 158 ? 6.45712   32.05065  -5.19325  1.000 35.02594 ? 156 LEU A CB  1 
ATOM   1260 C  CG  . LEU A 1 158 ? 6.42816   32.79541  -6.51988  1.000 35.13087 ? 156 LEU A CG  1 
ATOM   1261 C  CD1 . LEU A 1 158 ? 6.95279   31.88577  -7.60956  1.000 35.95142 ? 156 LEU A CD1 1 
ATOM   1262 C  CD2 . LEU A 1 158 ? 5.01485   33.26638  -6.82008  1.000 39.70603 ? 156 LEU A CD2 1 
ATOM   1263 N  N   . SER A 1 159 ? 5.01329   31.40466  -2.46194  1.000 34.77378 ? 157 SER A N   1 
ATOM   1264 C  CA  . SER A 1 159 ? 4.98868   30.33482  -1.46995  1.000 40.00394 ? 157 SER A CA  1 
ATOM   1265 C  C   . SER A 1 159 ? 5.14381   28.98675  -2.16362  1.000 36.32236 ? 157 SER A C   1 
ATOM   1266 O  O   . SER A 1 159 ? 4.59173   28.78005  -3.24762  1.000 35.68836 ? 157 SER A O   1 
ATOM   1267 C  CB  . SER A 1 159 ? 3.69040   30.35011  -0.65742  1.000 39.56118 ? 157 SER A CB  1 
ATOM   1268 O  OG  . SER A 1 159 ? 2.65444   29.65443  -1.32250  1.000 39.33730 ? 157 SER A OG  1 
ATOM   1269 N  N   . LEU A 1 160 ? 5.88819   28.07585  -1.51589  1.000 32.88640 ? 158 LEU A N   1 
ATOM   1270 C  CA  . LEU A 1 160 ? 6.04300   26.70667  -2.01080  1.000 36.29166 ? 158 LEU A CA  1 
ATOM   1271 C  C   . LEU A 1 160 ? 4.69240   26.03216  -2.21957  1.000 38.14194 ? 158 LEU A C   1 
ATOM   1272 O  O   . LEU A 1 160 ? 4.49657   25.30580  -3.20002  1.000 36.66369 ? 158 LEU A O   1 
ATOM   1273 C  CB  . LEU A 1 160 ? 6.90888   25.89427  -1.03899  1.000 37.32627 ? 158 LEU A CB  1 
ATOM   1274 C  CG  . LEU A 1 160 ? 7.58967   24.58662  -1.45938  1.000 38.99819 ? 158 LEU A CG  1 
ATOM   1275 C  CD1 . LEU A 1 160 ? 8.10253   24.63397  -2.90847  1.000 41.77101 ? 158 LEU A CD1 1 
ATOM   1276 C  CD2 . LEU A 1 160 ? 8.74017   24.28001  -0.51996  1.000 40.80336 ? 158 LEU A CD2 1 
ATOM   1277 N  N   . GLN A 1 161 ? 3.74768   26.25126  -1.30109  1.000 33.83573 ? 159 GLN A N   1 
ATOM   1278 C  CA  . GLN A 1 161 ? 2.40394   25.70925  -1.48059  1.000 35.51064 ? 159 GLN A CA  1 
ATOM   1279 C  C   . GLN A 1 161 ? 1.76940   26.18902  -2.78467  1.000 34.96765 ? 159 GLN A C   1 
ATOM   1280 O  O   . GLN A 1 161 ? 1.11972   25.40447  -3.48962  1.000 37.50663 ? 159 GLN A O   1 
ATOM   1281 C  CB  . GLN A 1 161 ? 1.52481   26.07011  -0.28016  1.000 35.97916 ? 159 GLN A CB  1 
ATOM   1282 C  CG  . GLN A 1 161 ? 1.88044   25.25008  0.97030   1.000 35.23210 ? 159 GLN A CG  1 
ATOM   1283 C  CD  . GLN A 1 161 ? 1.76559   23.74248  0.75261   1.000 35.53394 ? 159 GLN A CD  1 
ATOM   1284 O  OE1 . GLN A 1 161 ? 0.74312   23.24303  0.26818   1.000 35.14463 ? 159 GLN A OE1 1 
ATOM   1285 N  NE2 . GLN A 1 161 ? 2.82016   23.01155  1.11137   1.000 30.95983 ? 159 GLN A NE2 1 
ATOM   1286 N  N   . ASP A 1 162 ? 1.95782   27.46223  -3.13479  1.000 34.52674 ? 160 ASP A N   1 
ATOM   1287 C  CA  . ASP A 1 162 ? 1.43421   27.96668  -4.40233  1.000 34.04506 ? 160 ASP A CA  1 
ATOM   1288 C  C   . ASP A 1 162 ? 2.12258   27.29922  -5.59036  1.000 31.64344 ? 160 ASP A C   1 
ATOM   1289 O  O   . ASP A 1 162 ? 1.47938   26.98475  -6.59622  1.000 30.94897 ? 160 ASP A O   1 
ATOM   1290 C  CB  . ASP A 1 162 ? 1.63488   29.47862  -4.49262  1.000 37.76647 ? 160 ASP A CB  1 
ATOM   1291 C  CG  . ASP A 1 162 ? 0.59205   30.26388  -3.70672  1.000 43.18496 ? 160 ASP A CG  1 
ATOM   1292 O  OD1 . ASP A 1 162 ? -0.43352  29.69407  -3.27520  1.000 47.09377 ? 160 ASP A OD1 1 
ATOM   1293 O  OD2 . ASP A 1 162 ? 0.81895   31.45303  -3.51347  1.000 41.05811 ? 160 ASP A OD2 1 
ATOM   1294 N  N   . VAL A 1 163 ? 3.44339   27.13398  -5.50231  1.000 31.66699 ? 161 VAL A N   1 
ATOM   1295 C  CA  . VAL A 1 163 ? 4.22381   26.47230  -6.55188  1.000 34.19403 ? 161 VAL A CA  1 
ATOM   1296 C  C   . VAL A 1 163 ? 3.75926   25.02723  -6.75655  1.000 34.80318 ? 161 VAL A C   1 
ATOM   1297 O  O   . VAL A 1 163 ? 3.64281   24.54662  -7.89680  1.000 33.96164 ? 161 VAL A O   1 
ATOM   1298 C  CB  . VAL A 1 163 ? 5.72010   26.57165  -6.19064  1.000 33.34167 ? 161 VAL A CB  1 
ATOM   1299 C  CG1 . VAL A 1 163 ? 6.57437   25.66199  -7.05773  1.000 33.00553 ? 161 VAL A CG1 1 
ATOM   1300 C  CG2 . VAL A 1 163 ? 6.19843   28.07378  -6.29257  1.000 33.72252 ? 161 VAL A CG2 1 
ATOM   1301 N  N   . ILE A 1 164 ? 3.48330   24.30961  -5.66473  1.000 33.04522 ? 162 ILE A N   1 
ATOM   1302 C  CA  . ILE A 1 164 ? 2.94071   22.95696  -5.79248  1.000 31.55040 ? 162 ILE A CA  1 
ATOM   1303 C  C   . ILE A 1 164 ? 1.55901   22.99845  -6.43286  1.000 32.60954 ? 162 ILE A C   1 
ATOM   1304 O  O   . ILE A 1 164 ? 1.26103   22.24258  -7.36335  1.000 32.33868 ? 162 ILE A O   1 
ATOM   1305 C  CB  . ILE A 1 164 ? 2.89408   22.25592  -4.42158  1.000 34.09809 ? 162 ILE A CB  1 
ATOM   1306 C  CG1 . ILE A 1 164 ? 4.30929   22.06627  -3.85907  1.000 33.11582 ? 162 ILE A CG1 1 
ATOM   1307 C  CG2 . ILE A 1 164 ? 2.21160   20.89627  -4.56417  1.000 34.33241 ? 162 ILE A CG2 1 
ATOM   1308 C  CD1 . ILE A 1 164 ? 4.33789   21.57427  -2.44253  1.000 32.79298 ? 162 ILE A CD1 1 
ATOM   1309 N  N   . ALA A 1 165 ? 0.70363   23.90152  -5.95785  1.000 33.68333 ? 163 ALA A N   1 
ATOM   1310 C  CA  . ALA A 1 165 ? -0.68507  23.93172  -6.40497  1.000 34.58619 ? 163 ALA A CA  1 
ATOM   1311 C  C   . ALA A 1 165 ? -0.80184  24.15073  -7.91528  1.000 35.42798 ? 163 ALA A C   1 
ATOM   1312 O  O   . ALA A 1 165 ? -1.68160  23.56849  -8.55668  1.000 36.30025 ? 163 ALA A O   1 
ATOM   1313 C  CB  . ALA A 1 165 ? -1.44891  25.02908  -5.65417  1.000 37.83133 ? 163 ALA A CB  1 
ATOM   1314 N  N   . GLN A 1 166 ? 0.04597   25.00072  -8.50695  1.000 31.67687 ? 164 GLN A N   1 
ATOM   1315 C  CA  . GLN A 1 166 ? -0.19970  25.31383  -9.91785  1.000 32.11818 ? 164 GLN A CA  1 
ATOM   1316 C  C   . GLN A 1 166 ? 0.30302   24.25583  -10.87944 1.000 32.13748 ? 164 GLN A C   1 
ATOM   1317 O  O   . GLN A 1 166 ? 0.22846   24.47271  -12.09255 1.000 34.76374 ? 164 GLN A O   1 
ATOM   1318 C  CB  . GLN A 1 166 ? 0.42048   26.63925  -10.34441 1.000 37.32212 ? 164 GLN A CB  1 
ATOM   1319 C  CG  . GLN A 1 166 ? 1.75952   26.98439  -9.77202  1.000 38.99404 ? 164 GLN A CG  1 
ATOM   1320 C  CD  . GLN A 1 166 ? 2.04391   28.47000  -9.96515  1.000 38.21787 ? 164 GLN A CD  1 
ATOM   1321 O  OE1 . GLN A 1 166 ? 2.32714   28.92407  -11.08134 1.000 36.71594 ? 164 GLN A OE1 1 
ATOM   1322 N  NE2 . GLN A 1 166 ? 1.88119   29.24600  -8.89540  1.000 37.19910 ? 164 GLN A NE2 1 
ATOM   1323 N  N   . GLN A 1 167 ? 0.84109   23.14523  -10.38623 1.000 31.12236 ? 165 GLN A N   1 
ATOM   1324 C  CA  . GLN A 1 167 ? 1.03956   22.00387  -11.26225 1.000 32.81271 ? 165 GLN A CA  1 
ATOM   1325 C  C   . GLN A 1 167 ? -0.29630  21.44380  -11.76060 1.000 34.96875 ? 165 GLN A C   1 
ATOM   1326 O  O   . GLN A 1 167 ? -0.35656  20.83757  -12.83937 1.000 32.14652 ? 165 GLN A O   1 
ATOM   1327 C  CB  . GLN A 1 167 ? 1.84049   20.93420  -10.52006 1.000 32.93775 ? 165 GLN A CB  1 
ATOM   1328 C  CG  . GLN A 1 167 ? 2.24826   19.78130  -11.40683 1.000 31.49077 ? 165 GLN A CG  1 
ATOM   1329 C  CD  . GLN A 1 167 ? 2.77801   18.61825  -10.62562 1.000 33.00573 ? 165 GLN A CD  1 
ATOM   1330 O  OE1 . GLN A 1 167 ? 2.73885   18.60920  -9.39274  1.000 35.96122 ? 165 GLN A OE1 1 
ATOM   1331 N  NE2 . GLN A 1 167 ? 3.26817   17.62220  -11.33037 1.000 33.06255 ? 165 GLN A NE2 1 
ATOM   1332 N  N   . ASP A 1 168 ? -1.36868  21.63238  -10.98512 1.000 33.08250 ? 166 ASP A N   1 
ATOM   1333 C  CA  . ASP A 1 168 ? -2.71393  21.16025  -11.31442 1.000 29.24409 ? 166 ASP A CA  1 
ATOM   1334 C  C   . ASP A 1 168 ? -3.37351  22.13026  -12.30619 1.000 32.73214 ? 166 ASP A C   1 
ATOM   1335 O  O   . ASP A 1 168 ? -3.55445  23.31005  -11.99656 1.000 34.91589 ? 166 ASP A O   1 
ATOM   1336 C  CB  . ASP A 1 168 ? -3.49540  21.04913  -9.99837  1.000 31.93417 ? 166 ASP A CB  1 
ATOM   1337 C  CG  . ASP A 1 168 ? -4.95825  20.64788  -10.16326 1.000 34.24163 ? 166 ASP A CG  1 
ATOM   1338 O  OD1 . ASP A 1 168 ? -5.46969  20.46790  -11.28381 1.000 35.56785 ? 166 ASP A OD1 1 
ATOM   1339 O  OD2 . ASP A 1 168 ? -5.61751  20.51560  -9.11034  1.000 35.14946 ? 166 ASP A OD2 1 
ATOM   1340 N  N   . ASP A 1 169 ? -3.72601  21.64617  -13.50582 1.000 36.89462 ? 167 ASP A N   1 
ATOM   1341 C  CA  . ASP A 1 169 ? -4.41652  22.49838  -14.48300 1.000 35.64590 ? 167 ASP A CA  1 
ATOM   1342 C  C   . ASP A 1 169 ? -5.71234  23.08249  -13.91750 1.000 36.41032 ? 167 ASP A C   1 
ATOM   1343 O  O   . ASP A 1 169 ? -6.14911  24.14844  -14.35767 1.000 36.03396 ? 167 ASP A O   1 
ATOM   1344 C  CB  . ASP A 1 169 ? -4.75156  21.71208  -15.75985 1.000 33.17235 ? 167 ASP A CB  1 
ATOM   1345 C  CG  . ASP A 1 169 ? -3.54212  21.50262  -16.67333 1.000 31.16554 ? 167 ASP A CG  1 
ATOM   1346 O  OD1 . ASP A 1 169 ? -2.46673  22.04615  -16.36568 1.000 32.78259 ? 167 ASP A OD1 1 
ATOM   1347 O  OD2 . ASP A 1 169 ? -3.65521  20.76119  -17.68816 1.000 29.53108 ? 167 ASP A OD2 1 
ATOM   1348 N  N   . GLY A 1 170 ? -6.37042  22.37866  -12.99112 1.000 36.89495 ? 168 GLY A N   1 
ATOM   1349 C  CA  . GLY A 1 170 ? -7.61764  22.86669  -12.42405 1.000 38.65690 ? 168 GLY A CA  1 
ATOM   1350 C  C   . GLY A 1 170 ? -7.45249  23.93498  -11.36212 1.000 42.11041 ? 168 GLY A C   1 
ATOM   1351 O  O   . GLY A 1 170 ? -8.44922  24.52277  -10.90580 1.000 42.55229 ? 168 GLY A O   1 
ATOM   1352 N  N   . TYR A 1 171 ? -6.20998  24.19087  -10.95129 1.000 35.29335 ? 169 TYR A N   1 
ATOM   1353 C  CA  . TYR A 1 171 ? -5.94894  25.20853  -9.94439  1.000 39.08891 ? 169 TYR A CA  1 
ATOM   1354 C  C   . TYR A 1 171 ? -6.15590  26.59432  -10.53349 1.000 40.66869 ? 169 TYR A C   1 
ATOM   1355 O  O   . TYR A 1 171 ? -5.65971  26.89430  -11.61822 1.000 39.20701 ? 169 TYR A O   1 
ATOM   1356 C  CB  . TYR A 1 171 ? -4.52417  25.08084  -9.43094  1.000 40.13251 ? 169 TYR A CB  1 
ATOM   1357 C  CG  . TYR A 1 171 ? -4.07517  26.22864  -8.54507  1.000 38.03507 ? 169 TYR A CG  1 
ATOM   1358 C  CD1 . TYR A 1 171 ? -4.58714  26.38056  -7.25396  1.000 39.05148 ? 169 TYR A CD1 1 
ATOM   1359 C  CD2 . TYR A 1 171 ? -3.13058  27.14045  -8.98599  1.000 38.36474 ? 169 TYR A CD2 1 
ATOM   1360 C  CE1 . TYR A 1 171 ? -4.16345  27.42601  -6.42816  1.000 39.15493 ? 169 TYR A CE1 1 
ATOM   1361 C  CE2 . TYR A 1 171 ? -2.70445  28.20907  -8.17058  1.000 41.14125 ? 169 TYR A CE2 1 
ATOM   1362 C  CZ  . TYR A 1 171 ? -3.22364  28.33010  -6.88622  1.000 40.42407 ? 169 TYR A CZ  1 
ATOM   1363 O  OH  . TYR A 1 171 ? -2.79868  29.35844  -6.06926  1.000 42.21081 ? 169 TYR A OH  1 
ATOM   1364 N  N   . ASP A 1 172 ? -6.86795  27.45057  -9.78841  1.000 42.33866 ? 170 ASP A N   1 
ATOM   1365 C  CA  . ASP A 1 172 ? -7.37065  28.71897  -10.29215 1.000 43.67976 ? 170 ASP A CA  1 
ATOM   1366 C  C   . ASP A 1 172 ? -6.59296  29.93274  -9.81510  1.000 42.89631 ? 170 ASP A C   1 
ATOM   1367 O  O   . ASP A 1 172 ? -6.91231  31.04770  -10.23290 1.000 42.82922 ? 170 ASP A O   1 
ATOM   1368 C  CB  . ASP A 1 172 ? -8.83608  28.90779  -9.88351  1.000 52.50838 ? 170 ASP A CB  1 
ATOM   1369 C  CG  . ASP A 1 172 ? -9.77260  28.70594  -11.03112 1.000 58.66567 ? 170 ASP A CG  1 
ATOM   1370 O  OD1 . ASP A 1 172 ? -9.27657  28.68687  -12.17540 1.000 60.01294 ? 170 ASP A OD1 1 
ATOM   1371 O  OD2 . ASP A 1 172 ? -10.99513 28.59246  -10.79823 1.000 68.06037 ? 170 ASP A OD2 1 
ATOM   1372 N  N   . GLY A 1 173 ? -5.60607  29.76557  -8.94704  1.000 40.51656 ? 171 GLY A N   1 
ATOM   1373 C  CA  . GLY A 1 173 ? -4.92252  30.90550  -8.37724  1.000 39.38589 ? 171 GLY A CA  1 
ATOM   1374 C  C   . GLY A 1 173 ? -4.03093  31.63567  -9.36163  1.000 43.85311 ? 171 GLY A C   1 
ATOM   1375 O  O   . GLY A 1 173 ? -4.01007  31.35054  -10.56565 1.000 42.87276 ? 171 GLY A O   1 
ATOM   1376 N  N   . PRO A 1 174 ? -3.27475  32.60879  -8.85704  1.000 45.71100 ? 172 PRO A N   1 
ATOM   1377 C  CA  . PRO A 1 174 ? -2.42440  33.41168  -9.74201  1.000 41.68668 ? 172 PRO A CA  1 
ATOM   1378 C  C   . PRO A 1 174 ? -1.26144  32.59911  -10.28756 1.000 44.01843 ? 172 PRO A C   1 
ATOM   1379 O  O   . PRO A 1 174 ? -0.63216  31.81874  -9.56915  1.000 39.31861 ? 172 PRO A O   1 
ATOM   1380 C  CB  . PRO A 1 174 ? -1.92713  34.55057  -8.84014  1.000 42.90419 ? 172 PRO A CB  1 
ATOM   1381 C  CG  . PRO A 1 174 ? -2.70514  34.47215  -7.58069  1.000 39.11353 ? 172 PRO A CG  1 
ATOM   1382 C  CD  . PRO A 1 174 ? -3.26451  33.09135  -7.46425  1.000 44.58422 ? 172 PRO A CD  1 
ATOM   1383 N  N   . ARG A 1 175 ? -0.97310  32.81981  -11.57158 1.000 38.49404 ? 173 ARG A N   1 
ATOM   1384 C  CA  . ARG A 1 175 ? 0.13108   32.19893  -12.27856 1.000 40.92229 ? 173 ARG A CA  1 
ATOM   1385 C  C   . ARG A 1 175 ? 0.95957   33.25985  -12.97766 1.000 41.14747 ? 173 ARG A C   1 
ATOM   1386 O  O   . ARG A 1 175 ? 0.43133   34.27233  -13.45019 1.000 41.47691 ? 173 ARG A O   1 
ATOM   1387 C  CB  . ARG A 1 175 ? -0.35795  31.23173  -13.33120 1.000 42.11581 ? 173 ARG A CB  1 
ATOM   1388 C  CG  . ARG A 1 175 ? -1.17339  30.14160  -12.79024 1.000 40.31405 ? 173 ARG A CG  1 
ATOM   1389 C  CD  . ARG A 1 175 ? -1.35727  29.11033  -13.84348 1.000 39.23476 ? 173 ARG A CD  1 
ATOM   1390 N  NE  . ARG A 1 175 ? -2.34020  28.14722  -13.38634 1.000 38.18191 ? 173 ARG A NE  1 
ATOM   1391 C  CZ  . ARG A 1 175 ? -2.23239  26.84184  -13.56509 1.000 35.63675 ? 173 ARG A CZ  1 
ATOM   1392 N  NH1 . ARG A 1 175 ? -1.25060  26.32896  -14.29238 1.000 33.80667 ? 173 ARG A NH1 1 
ATOM   1393 N  NH2 . ARG A 1 175 ? -3.12276  26.03361  -12.98931 1.000 36.39140 ? 173 ARG A NH2 1 
ATOM   1394 N  N   . SER A 1 176 ? 2.26465   33.01722  -13.04287 1.000 36.42034 ? 174 SER A N   1 
ATOM   1395 C  CA  . SER A 1 176 ? 3.14652   33.82750  -13.86652 1.000 39.62914 ? 174 SER A CA  1 
ATOM   1396 C  C   . SER A 1 176 ? 4.13334   32.90179  -14.55749 1.000 38.47111 ? 174 SER A C   1 
ATOM   1397 O  O   . SER A 1 176 ? 4.24942   31.71843  -14.21378 1.000 39.54730 ? 174 SER A O   1 
ATOM   1398 C  CB  . SER A 1 176 ? 3.87960   34.89113  -13.03610 1.000 36.55159 ? 174 SER A CB  1 
ATOM   1399 O  OG  . SER A 1 176 ? 4.78205   34.30398  -12.10366 1.000 37.30247 ? 174 SER A OG  1 
ATOM   1400 N  N   . GLY A 1 177 ? 4.81909   33.43206  -15.57148 1.000 37.27627 ? 175 GLY A N   1 
ATOM   1401 C  CA  . GLY A 1 177 ? 5.88927   32.65742  -16.17786 1.000 33.97725 ? 175 GLY A CA  1 
ATOM   1402 C  C   . GLY A 1 177 ? 6.90713   32.24245  -15.14298 1.000 37.36650 ? 175 GLY A C   1 
ATOM   1403 O  O   . GLY A 1 177 ? 7.31382   31.08008  -15.08622 1.000 36.35703 ? 175 GLY A O   1 
ATOM   1404 N  N   . GLY A 1 178 ? 7.27344   33.17390  -14.25967 1.000 37.27894 ? 176 GLY A N   1 
ATOM   1405 C  CA  . GLY A 1 178 ? 8.23016   32.86244  -13.21270 1.000 35.46259 ? 176 GLY A CA  1 
ATOM   1406 C  C   . GLY A 1 178 ? 7.75966   31.74721  -12.29482 1.000 34.69337 ? 176 GLY A C   1 
ATOM   1407 O  O   . GLY A 1 178 ? 8.53713   30.86205  -11.93492 1.000 30.41746 ? 176 GLY A O   1 
ATOM   1408 N  N   . SER A 1 179 ? 6.48964   31.78346  -11.88248 1.000 34.96123 ? 177 SER A N   1 
ATOM   1409 C  CA  . SER A 1 179 ? 6.03526   30.79056  -10.91431 1.000 34.01187 ? 177 SER A CA  1 
ATOM   1410 C  C   . SER A 1 179 ? 5.87895   29.41376  -11.56574 1.000 33.88002 ? 177 SER A C   1 
ATOM   1411 O  O   . SER A 1 179 ? 6.23375   28.39431  -10.96403 1.000 34.48757 ? 177 SER A O   1 
ATOM   1412 C  CB  . SER A 1 179 ? 4.72984   31.23071  -10.26116 1.000 33.04107 ? 177 SER A CB  1 
ATOM   1413 O  OG  . SER A 1 179 ? 3.68377   31.31480  -11.19629 1.000 32.31382 ? 177 SER A OG  1 
ATOM   1414 N  N   . GLN A 1 180 ? 5.34984   29.36046  -12.79123 1.000 32.77765 ? 178 GLN A N   1 
ATOM   1415 C  CA  . GLN A 1 180 ? 5.21964   28.06664  -13.45062 1.000 31.97794 ? 178 GLN A CA  1 
ATOM   1416 C  C   . GLN A 1 180 ? 6.58449   27.49678  -13.79057 1.000 33.99198 ? 178 GLN A C   1 
ATOM   1417 O  O   . GLN A 1 180 ? 6.77576   26.27038  -13.74510 1.000 29.76239 ? 178 GLN A O   1 
ATOM   1418 C  CB  . GLN A 1 180 ? 4.33451   28.19204  -14.69606 1.000 32.86584 ? 178 GLN A CB  1 
ATOM   1419 C  CG  . GLN A 1 180 ? 2.92077   28.73569  -14.33993 1.000 33.63792 ? 178 GLN A CG  1 
ATOM   1420 C  CD  . GLN A 1 180 ? 1.89341   28.53160  -15.43082 1.000 35.01753 ? 178 GLN A CD  1 
ATOM   1421 O  OE1 . GLN A 1 180 ? 1.26776   27.46774  -15.52284 1.000 35.02958 ? 178 GLN A OE1 1 
ATOM   1422 N  NE2 . GLN A 1 180 ? 1.67975   29.57075  -16.25176 1.000 34.62725 ? 178 GLN A NE2 1 
ATOM   1423 N  N   . SER A 1 181 ? 7.55501   28.36245  -14.08979 1.000 31.05015 ? 179 SER A N   1 
ATOM   1424 C  CA  . SER A 1 181 ? 8.91682   27.88106  -14.28123 1.000 32.54739 ? 179 SER A CA  1 
ATOM   1425 C  C   . SER A 1 181 ? 9.45949   27.26783  -12.99500 1.000 30.19163 ? 179 SER A C   1 
ATOM   1426 O  O   . SER A 1 181 ? 10.00764  26.16552  -13.00410 1.000 30.67607 ? 179 SER A O   1 
ATOM   1427 C  CB  . SER A 1 181 ? 9.81493   29.01570  -14.78461 1.000 35.08363 ? 179 SER A CB  1 
ATOM   1428 O  OG  . SER A 1 181 ? 9.59074   29.24472  -16.17168 1.000 33.07772 ? 179 SER A OG  1 
ATOM   1429 N  N   . LEU A 1 182 ? 9.30224   27.96447  -11.86935 1.000 31.07776 ? 180 LEU A N   1 
ATOM   1430 C  CA  . LEU A 1 182 ? 9.77377   27.42182  -10.60015 1.000 28.67878 ? 180 LEU A CA  1 
ATOM   1431 C  C   . LEU A 1 182 ? 9.02901   26.15276  -10.21428 1.000 27.59247 ? 180 LEU A C   1 
ATOM   1432 O  O   . LEU A 1 182 ? 9.58238   25.30480  -9.49768  1.000 29.44244 ? 180 LEU A O   1 
ATOM   1433 C  CB  . LEU A 1 182 ? 9.64389   28.48690  -9.50264  1.000 28.87376 ? 180 LEU A CB  1 
ATOM   1434 C  CG  . LEU A 1 182 ? 10.77198  29.51632  -9.63879  1.000 31.21395 ? 180 LEU A CG  1 
ATOM   1435 C  CD1 . LEU A 1 182 ? 10.46099  30.85199  -8.91938  1.000 32.94741 ? 180 LEU A CD1 1 
ATOM   1436 C  CD2 . LEU A 1 182 ? 12.07167  28.88618  -9.13340  1.000 33.55479 ? 180 LEU A CD2 1 
ATOM   1437 N  N   . ALA A 1 183 ? 7.77533   26.00880  -10.65592 1.000 27.91834 ? 181 ALA A N   1 
ATOM   1438 C  CA  . ALA A 1 183 ? 7.05415   24.75585  -10.43845 1.000 28.45300 ? 181 ALA A CA  1 
ATOM   1439 C  C   . ALA A 1 183 ? 7.67877   23.60686  -11.23832 1.000 32.10512 ? 181 ALA A C   1 
ATOM   1440 O  O   . ALA A 1 183 ? 7.90673   22.51403  -10.70391 1.000 28.96816 ? 181 ALA A O   1 
ATOM   1441 C  CB  . ALA A 1 183 ? 5.57891   24.94347  -10.79696 1.000 28.88846 ? 181 ALA A CB  1 
ATOM   1442 N  N   . LEU A 1 184 ? 7.97046   23.83104  -12.52992 1.000 29.45492 ? 182 LEU A N   1 
ATOM   1443 C  CA  . LEU A 1 184 ? 8.67119   22.80265  -13.29495 1.000 29.74102 ? 182 LEU A CA  1 
ATOM   1444 C  C   . LEU A 1 184 ? 10.00439  22.44262  -12.64318 1.000 30.36416 ? 182 LEU A C   1 
ATOM   1445 O  O   . LEU A 1 184 ? 10.42818  21.28666  -12.70201 1.000 30.33068 ? 182 LEU A O   1 
ATOM   1446 C  CB  . LEU A 1 184 ? 8.90195   23.26464  -14.75504 1.000 28.52418 ? 182 LEU A CB  1 
ATOM   1447 C  CG  . LEU A 1 184 ? 7.67681   23.46654  -15.65953 1.000 28.37831 ? 182 LEU A CG  1 
ATOM   1448 C  CD1 . LEU A 1 184 ? 8.05063   23.98832  -17.05717 1.000 28.44595 ? 182 LEU A CD1 1 
ATOM   1449 C  CD2 . LEU A 1 184 ? 6.84893   22.19529  -15.79590 1.000 28.26747 ? 182 LEU A CD2 1 
ATOM   1450 N  N   . VAL A 1 185 ? 10.68612  23.40998  -12.02101 1.000 28.69934 ? 183 VAL A N   1 
ATOM   1451 C  CA  . VAL A 1 185 ? 11.92844  23.07096  -11.33333 1.000 29.40858 ? 183 VAL A CA  1 
ATOM   1452 C  C   . VAL A 1 185 ? 11.63212  22.20348  -10.13059 1.000 30.21855 ? 183 VAL A C   1 
ATOM   1453 O  O   . VAL A 1 185 ? 12.31291  21.19914  -9.88146  1.000 31.67079 ? 183 VAL A O   1 
ATOM   1454 C  CB  . VAL A 1 185 ? 12.68950  24.34082  -10.90527 1.000 31.26444 ? 183 VAL A CB  1 
ATOM   1455 C  CG1 . VAL A 1 185 ? 13.83877  23.95144  -9.96954  1.000 29.92733 ? 183 VAL A CG1 1 
ATOM   1456 C  CG2 . VAL A 1 185 ? 13.19702  25.09118  -12.11726 1.000 30.30593 ? 183 VAL A CG2 1 
ATOM   1457 N  N   . ARG A 1 186 ? 10.61778  22.59360  -9.35638  1.000 29.25389 ? 184 ARG A N   1 
ATOM   1458 C  CA  . ARG A 1 186 ? 10.18865  21.80378  -8.20857  1.000 30.56513 ? 184 ARG A CA  1 
ATOM   1459 C  C   . ARG A 1 186 ? 9.91872   20.35958  -8.61277  1.000 31.35133 ? 184 ARG A C   1 
ATOM   1460 O  O   . ARG A 1 186 ? 10.45350  19.41444  -8.01498  1.000 27.05047 ? 184 ARG A O   1 
ATOM   1461 C  CB  . ARG A 1 186 ? 8.92264   22.41619  -7.61385  1.000 30.67961 ? 184 ARG A CB  1 
ATOM   1462 C  CG  . ARG A 1 186 ? 8.73643   22.13964  -6.13826  1.000 33.97670 ? 184 ARG A CG  1 
ATOM   1463 C  CD  . ARG A 1 186 ? 7.68589   21.12950  -5.79945  1.000 35.09470 ? 184 ARG A CD  1 
ATOM   1464 N  NE  . ARG A 1 186 ? 6.48005   20.99013  -6.61620  1.000 36.01639 ? 184 ARG A NE  1 
ATOM   1465 C  CZ  . ARG A 1 186 ? 5.70933   19.90450  -6.53250  1.000 33.48375 ? 184 ARG A CZ  1 
ATOM   1466 N  NH1 . ARG A 1 186 ? 5.98396   18.93447  -5.67816  1.000 35.37183 ? 184 ARG A NH1 1 
ATOM   1467 N  NH2 . ARG A 1 186 ? 4.64515   19.78353  -7.32451  1.000 31.44867 ? 184 ARG A NH2 1 
ATOM   1468 N  N   . GLU A 1 187 ? 9.06498   20.18959  -9.62656  1.000 32.54354 ? 185 GLU A N   1 
ATOM   1469 C  CA  . GLU A 1 187 ? 8.67207   18.86747  -10.10176 1.000 31.56926 ? 185 GLU A CA  1 
ATOM   1470 C  C   . GLU A 1 187 ? 9.88062   18.04844  -10.54347 1.000 33.04853 ? 185 GLU A C   1 
ATOM   1471 O  O   . GLU A 1 187 ? 9.93919   16.82588  -10.31863 1.000 34.35405 ? 185 GLU A O   1 
ATOM   1472 C  CB  . GLU A 1 187 ? 7.66631   19.03974  -11.24298 1.000 30.47062 ? 185 GLU A CB  1 
ATOM   1473 C  CG  . GLU A 1 187 ? 6.29536   19.58800  -10.79463 1.000 26.97399 ? 185 GLU A CG  1 
ATOM   1474 C  CD  . GLU A 1 187 ? 5.63410   20.44774  -11.83947 1.000 32.32889 ? 185 GLU A CD  1 
ATOM   1475 O  OE1 . GLU A 1 187 ? 5.66556   20.08945  -13.03622 1.000 29.00299 ? 185 GLU A OE1 1 
ATOM   1476 O  OE2 . GLU A 1 187 ? 5.06708   21.51316  -11.47267 1.000 32.61845 ? 185 GLU A OE2 1 
ATOM   1477 N  N   . ALA A 1 188 ? 10.83556  18.69076  -11.20277 1.000 32.00301 ? 186 ALA A N   1 
ATOM   1478 C  CA  . ALA A 1 188 ? 12.01704  17.98066  -11.65924 1.000 32.31909 ? 186 ALA A CA  1 
ATOM   1479 C  C   . ALA A 1 188 ? 12.89307  17.58442  -10.48737 1.000 32.05120 ? 186 ALA A C   1 
ATOM   1480 O  O   . ALA A 1 188 ? 13.51375  16.51248  -10.49697 1.000 32.21094 ? 186 ALA A O   1 
ATOM   1481 C  CB  . ALA A 1 188 ? 12.80198  18.84556  -12.64217 1.000 30.88261 ? 186 ALA A CB  1 
ATOM   1482 N  N   . MET A 1 189 ? 12.94007  18.43869  -9.46972  1.000 31.07823 ? 187 MET A N   1 
ATOM   1483 C  CA  . MET A 1 189 ? 13.70953  18.15836  -8.26633  1.000 33.45639 ? 187 MET A CA  1 
ATOM   1484 C  C   . MET A 1 189 ? 13.13329  16.98634  -7.48961  1.000 30.00786 ? 187 MET A C   1 
ATOM   1485 O  O   . MET A 1 189 ? 13.88659  16.19158  -6.91615  1.000 31.76666 ? 187 MET A O   1 
ATOM   1486 C  CB  . MET A 1 189 ? 13.74028  19.38626  -7.36007  1.000 31.44027 ? 187 MET A CB  1 
ATOM   1487 C  CG  . MET A 1 189 ? 14.61604  20.50552  -7.85566  1.000 28.84112 ? 187 MET A CG  1 
ATOM   1488 S  SD  . MET A 1 189 ? 14.62870  21.89429  -6.71581  1.000 31.91557 ? 187 MET A SD  1 
ATOM   1489 C  CE  . MET A 1 189 ? 15.89749  21.32936  -5.57597  1.000 34.84856 ? 187 MET A CE  1 
ATOM   1490 N  N   . LEU A 1 190 ? 11.80751  16.90475  -7.40134  1.000 27.81562 ? 188 LEU A N   1 
ATOM   1491 C  CA  . LEU A 1 190 ? 11.18168  15.79111  -6.69272  1.000 34.52470 ? 188 LEU A CA  1 
ATOM   1492 C  C   . LEU A 1 190 ? 11.42530  14.47410  -7.42472  1.000 31.36086 ? 188 LEU A C   1 
ATOM   1493 O  O   . LEU A 1 190 ? 11.72120  13.45144  -6.79399  1.000 30.71301 ? 188 LEU A O   1 
ATOM   1494 C  CB  . LEU A 1 190 ? 9.68509   16.05177  -6.52191  1.000 31.82826 ? 188 LEU A CB  1 
ATOM   1495 C  CG  . LEU A 1 190 ? 8.98486   15.19130  -5.45960  1.000 40.99859 ? 188 LEU A CG  1 
ATOM   1496 C  CD1 . LEU A 1 190 ? 9.68943   15.33490  -4.12435  1.000 38.28197 ? 188 LEU A CD1 1 
ATOM   1497 C  CD2 . LEU A 1 190 ? 7.50741   15.57244  -5.33636  1.000 43.11339 ? 188 LEU A CD2 1 
ATOM   1498 N  N   . ARG A 1 191 ? 11.34592  14.49654  -8.76060  1.000 30.44728 ? 189 ARG A N   1 
ATOM   1499 C  CA  . ARG A 1 191 ? 11.64434  13.30403  -9.54693  1.000 31.08288 ? 189 ARG A CA  1 
ATOM   1500 C  C   . ARG A 1 191 ? 13.06496  12.82086  -9.28691  1.000 35.22836 ? 189 ARG A C   1 
ATOM   1501 O  O   . ARG A 1 191 ? 13.30496  11.61477  -9.12497  1.000 32.88016 ? 189 ARG A O   1 
ATOM   1502 C  CB  . ARG A 1 191 ? 11.44954  13.58622  -11.04576 1.000 30.69465 ? 189 ARG A CB  1 
ATOM   1503 C  CG  . ARG A 1 191 ? 9.97441   13.62875  -11.41889 1.000 31.24068 ? 189 ARG A CG  1 
ATOM   1504 C  CD  . ARG A 1 191 ? 9.69251   13.78662  -12.91164 1.000 35.84197 ? 189 ARG A CD  1 
ATOM   1505 N  NE  . ARG A 1 191 ? 10.40159  14.92127  -13.50275 1.000 34.45226 ? 189 ARG A NE  1 
ATOM   1506 C  CZ  . ARG A 1 191 ? 9.80496   16.05104  -13.87321 1.000 36.43381 ? 189 ARG A CZ  1 
ATOM   1507 N  NH1 . ARG A 1 191 ? 8.54155   16.30213  -13.54990 1.000 35.25361 ? 189 ARG A NH1 1 
ATOM   1508 N  NH2 . ARG A 1 191 ? 10.49883  16.96476  -14.56214 1.000 33.67294 ? 189 ARG A NH2 1 
ATOM   1509 N  N   . LEU A 1 192 ? 14.02560  13.74600  -9.25679  1.000 32.89880 ? 190 LEU A N   1 
ATOM   1510 C  CA  . LEU A 1 192 ? 15.40203  13.35560  -8.97880  1.000 30.89046 ? 190 LEU A CA  1 
ATOM   1511 C  C   . LEU A 1 192 ? 15.50633  12.66348  -7.62315  1.000 32.76078 ? 190 LEU A C   1 
ATOM   1512 O  O   . LEU A 1 192 ? 16.04583  11.55312  -7.51227  1.000 32.78502 ? 190 LEU A O   1 
ATOM   1513 C  CB  . LEU A 1 192 ? 16.30309  14.59004  -9.03619  1.000 30.70974 ? 190 LEU A CB  1 
ATOM   1514 C  CG  . LEU A 1 192 ? 17.72418  14.35950  -8.53461  1.000 32.41063 ? 190 LEU A CG  1 
ATOM   1515 C  CD1 . LEU A 1 192 ? 18.38366  13.22078  -9.28022  1.000 30.30661 ? 190 LEU A CD1 1 
ATOM   1516 C  CD2 . LEU A 1 192 ? 18.57072  15.62638  -8.60149  1.000 33.53166 ? 190 LEU A CD2 1 
ATOM   1517 N  N   . ASP A 1 193 ? 14.96506  13.29788  -6.58242  1.000 33.10777 ? 191 ASP A N   1 
ATOM   1518 C  CA  . ASP A 1 193 ? 15.05244  12.74547  -5.23561  1.000 33.16001 ? 191 ASP A CA  1 
ATOM   1519 C  C   . ASP A 1 193 ? 14.33813  11.40003  -5.14728  1.000 33.49096 ? 191 ASP A C   1 
ATOM   1520 O  O   . ASP A 1 193 ? 14.86480  10.43492  -4.56721  1.000 32.60052 ? 191 ASP A O   1 
ATOM   1521 C  CB  . ASP A 1 193 ? 14.47889  13.78191  -4.25996  1.000 31.43043 ? 191 ASP A CB  1 
ATOM   1522 C  CG  . ASP A 1 193 ? 14.96976  13.61037  -2.83886  1.000 35.98189 ? 191 ASP A CG  1 
ATOM   1523 O  OD1 . ASP A 1 193 ? 15.80299  12.72829  -2.55426  1.000 38.02377 ? 191 ASP A OD1 1 
ATOM   1524 O  OD2 . ASP A 1 193 ? 14.53105  14.39576  -1.98109  1.000 35.63181 ? 191 ASP A OD2 1 
ATOM   1525 N  N   . GLY A 1 194 ? 13.14459  11.30524  -5.73915  1.000 33.54751 ? 192 GLY A N   1 
ATOM   1526 C  CA  . GLY A 1 194 ? 12.45222  10.02833  -5.78691  1.000 31.54503 ? 192 GLY A CA  1 
ATOM   1527 C  C   . GLY A 1 194 ? 13.27990  8.94551   -6.46126  1.000 34.92306 ? 192 GLY A C   1 
ATOM   1528 O  O   . GLY A 1 194 ? 13.31391  7.79739   -6.00447  1.000 34.14745 ? 192 GLY A O   1 
ATOM   1529 N  N   . SER A 1 195 ? 13.96575  9.29692   -7.55306  1.000 35.19136 ? 193 SER A N   1 
ATOM   1530 C  CA  . SER A 1 195 ? 14.84491  8.33306   -8.20766  1.000 33.32828 ? 193 SER A CA  1 
ATOM   1531 C  C   . SER A 1 195 ? 15.97424  7.90952   -7.27737  1.000 34.84861 ? 193 SER A C   1 
ATOM   1532 O  O   . SER A 1 195 ? 16.33282  6.73247   -7.22763  1.000 32.22455 ? 193 SER A O   1 
ATOM   1533 C  CB  . SER A 1 195 ? 15.40788  8.92211   -9.50360  1.000 31.21992 ? 193 SER A CB  1 
ATOM   1534 O  OG  . SER A 1 195 ? 16.38520  8.06242   -10.08665 1.000 32.33655 ? 193 SER A OG  1 
ATOM   1535 N  N   . VAL A 1 196 ? 16.53729  8.85390   -6.51784  1.000 32.98538 ? 194 VAL A N   1 
ATOM   1536 C  CA  . VAL A 1 196 ? 17.63261  8.51425   -5.60869  1.000 36.65220 ? 194 VAL A CA  1 
ATOM   1537 C  C   . VAL A 1 196 ? 17.13048  7.62433   -4.46610  1.000 34.92658 ? 194 VAL A C   1 
ATOM   1538 O  O   . VAL A 1 196 ? 17.82078  6.69067   -4.03426  1.000 35.91266 ? 194 VAL A O   1 
ATOM   1539 C  CB  . VAL A 1 196 ? 18.29617  9.81027   -5.09011  1.000 34.78811 ? 194 VAL A CB  1 
ATOM   1540 C  CG1 . VAL A 1 196 ? 19.27259  9.52188   -3.96291  1.000 36.42754 ? 194 VAL A CG1 1 
ATOM   1541 C  CG2 . VAL A 1 196 ? 18.99367  10.53033  -6.23490  1.000 36.31789 ? 194 VAL A CG2 1 
ATOM   1542 N  N   . LEU A 1 197 ? 15.93120  7.90845   -3.95224  1.000 35.26696 ? 195 LEU A N   1 
ATOM   1543 C  CA  . LEU A 1 197 ? 15.31472  7.04346   -2.94897  1.000 37.06298 ? 195 LEU A CA  1 
ATOM   1544 C  C   . LEU A 1 197 ? 15.03696  5.66590   -3.53233  1.000 37.50717 ? 195 LEU A C   1 
ATOM   1545 O  O   . LEU A 1 197 ? 15.11558  4.65587   -2.82138  1.000 33.66871 ? 195 LEU A O   1 
ATOM   1546 C  CB  . LEU A 1 197 ? 14.01284  7.67497   -2.43296  1.000 36.70895 ? 195 LEU A CB  1 
ATOM   1547 C  CG  . LEU A 1 197 ? 14.08778  8.96609   -1.59687  1.000 38.21663 ? 195 LEU A CG  1 
ATOM   1548 C  CD1 . LEU A 1 197 ? 12.68965  9.56285   -1.39832  1.000 37.30401 ? 195 LEU A CD1 1 
ATOM   1549 C  CD2 . LEU A 1 197 ? 14.77198  8.71955   -0.25283  1.000 38.88004 ? 195 LEU A CD2 1 
ATOM   1550 N  N   . GLY A 1 198 ? 14.73451  5.61096   -4.83216  1.000 37.61955 ? 196 GLY A N   1 
ATOM   1551 C  CA  . GLY A 1 198 ? 14.65454  4.32944   -5.51105  1.000 32.70805 ? 196 GLY A CA  1 
ATOM   1552 C  C   . GLY A 1 198 ? 15.98290  3.59803   -5.51015  1.000 35.68297 ? 196 GLY A C   1 
ATOM   1553 O  O   . GLY A 1 198 ? 16.04266  2.39767   -5.22266  1.000 37.18178 ? 196 GLY A O   1 
ATOM   1554 N  N   . TRP A 1 199 ? 17.07437  4.31082   -5.81848  1.000 33.63019 ? 197 TRP A N   1 
ATOM   1555 C  CA  . TRP A 1 199 ? 18.38216  3.66745   -5.72416  1.000 35.22130 ? 197 TRP A CA  1 
ATOM   1556 C  C   . TRP A 1 199 ? 18.58962  3.06987   -4.33993  1.000 35.34079 ? 197 TRP A C   1 
ATOM   1557 O  O   . TRP A 1 199 ? 18.99239  1.91609   -4.20993  1.000 36.81296 ? 197 TRP A O   1 
ATOM   1558 C  CB  . TRP A 1 199 ? 19.53294  4.63298   -6.04659  1.000 30.75764 ? 197 TRP A CB  1 
ATOM   1559 C  CG  . TRP A 1 199 ? 20.86024  3.87704   -5.94385  1.000 35.42367 ? 197 TRP A CG  1 
ATOM   1560 C  CD1 . TRP A 1 199 ? 21.47522  3.17273   -6.94640  1.000 37.36933 ? 197 TRP A CD1 1 
ATOM   1561 C  CD2 . TRP A 1 199 ? 21.68213  3.70096   -4.77359  1.000 35.55677 ? 197 TRP A CD2 1 
ATOM   1562 N  NE1 . TRP A 1 199 ? 22.63370  2.58357   -6.47758  1.000 38.67745 ? 197 TRP A NE1 1 
ATOM   1563 C  CE2 . TRP A 1 199 ? 22.78774  2.90231   -5.15149  1.000 39.05615 ? 197 TRP A CE2 1 
ATOM   1564 C  CE3 . TRP A 1 199 ? 21.59545  4.14433   -3.44704  1.000 36.76443 ? 197 TRP A CE3 1 
ATOM   1565 C  CZ2 . TRP A 1 199 ? 23.79546  2.53439   -4.24657  1.000 39.12432 ? 197 TRP A CZ2 1 
ATOM   1566 C  CZ3 . TRP A 1 199 ? 22.60437  3.78128   -2.55052  1.000 40.21827 ? 197 TRP A CZ3 1 
ATOM   1567 C  CH2 . TRP A 1 199 ? 23.68172  2.97518   -2.95508  1.000 39.72380 ? 197 TRP A CH2 1 
ATOM   1568 N  N   . LYS A 1 200 ? 18.31767  3.84668   -3.28805  1.000 38.06205 ? 198 LYS A N   1 
ATOM   1569 C  CA  . LYS A 1 200 ? 18.60064  3.37038   -1.93657  1.000 36.17619 ? 198 LYS A CA  1 
ATOM   1570 C  C   . LYS A 1 200 ? 17.81647  2.10813   -1.62024  1.000 35.62702 ? 198 LYS A C   1 
ATOM   1571 O  O   . LYS A 1 200 ? 18.34687  1.17411   -1.00819  1.000 37.59701 ? 198 LYS A O   1 
ATOM   1572 C  CB  . LYS A 1 200 ? 18.29275  4.48089   -0.93167  1.000 36.53051 ? 198 LYS A CB  1 
ATOM   1573 C  CG  . LYS A 1 200 ? 19.31510  5.63148   -0.99521  1.000 38.05815 ? 198 LYS A CG  1 
ATOM   1574 C  CD  . LYS A 1 200 ? 19.03180  6.71109   0.05128   1.000 40.33036 ? 198 LYS A CD  1 
ATOM   1575 C  CE  . LYS A 1 200 ? 20.17022  7.74183   0.13216   1.000 48.29060 ? 198 LYS A CE  1 
ATOM   1576 N  NZ  . LYS A 1 200 ? 20.07206  8.59018   1.37603   1.000 51.26527 ? 198 LYS A NZ  1 
ATOM   1577 N  N   . GLN A 1 201 ? 16.55638  2.05103   -2.04340  1.000 34.50562 ? 199 GLN A N   1 
ATOM   1578 C  CA  . GLN A 1 201 ? 15.74592  0.87275   -1.77721  1.000 37.79628 ? 199 GLN A CA  1 
ATOM   1579 C  C   . GLN A 1 201 ? 16.19035  -0.32246  -2.61606  1.000 38.60842 ? 199 GLN A C   1 
ATOM   1580 O  O   . GLN A 1 201 ? 16.25541  -1.44373  -2.10143  1.000 39.00010 ? 199 GLN A O   1 
ATOM   1581 C  CB  . GLN A 1 201 ? 14.26754  1.19022   -2.01505  1.000 36.55982 ? 199 GLN A CB  1 
ATOM   1582 C  CG  . GLN A 1 201 ? 13.68707  2.21942   -1.04351  1.000 41.77320 ? 199 GLN A CG  1 
ATOM   1583 C  CD  . GLN A 1 201 ? 13.64241  1.70631   0.38795   1.000 42.79868 ? 199 GLN A CD  1 
ATOM   1584 O  OE1 . GLN A 1 201 ? 13.51858  0.50506   0.62220   1.000 44.41542 ? 199 GLN A OE1 1 
ATOM   1585 N  NE2 . GLN A 1 201 ? 13.70187  2.62141   1.34684   1.000 50.84061 ? 199 GLN A NE2 1 
ATOM   1586 N  N   . HIS A 1 202 ? 16.49077  -0.12319  -3.90849  1.000 37.40045 ? 200 HIS A N   1 
ATOM   1587 C  CA  . HIS A 1 202 ? 16.93209  -1.26396  -4.71833  1.000 35.71915 ? 200 HIS A CA  1 
ATOM   1588 C  C   . HIS A 1 202 ? 18.27367  -1.79094  -4.22333  1.000 38.94598 ? 200 HIS A C   1 
ATOM   1589 O  O   . HIS A 1 202 ? 18.51391  -3.00541  -4.22353  1.000 35.23558 ? 200 HIS A O   1 
ATOM   1590 C  CB  . HIS A 1 202 ? 17.02193  -0.88662  -6.20928  1.000 35.83805 ? 200 HIS A CB  1 
ATOM   1591 C  CG  . HIS A 1 202 ? 15.70069  -0.92311  -6.90668  1.000 33.42351 ? 200 HIS A CG  1 
ATOM   1592 N  ND1 . HIS A 1 202 ? 15.02830  -2.09472  -7.15440  1.000 36.78520 ? 200 HIS A ND1 1 
ATOM   1593 C  CD2 . HIS A 1 202 ? 14.90364  0.07084   -7.36492  1.000 34.96969 ? 200 HIS A CD2 1 
ATOM   1594 C  CE1 . HIS A 1 202 ? 13.87905  -1.82559  -7.74758  1.000 34.80127 ? 200 HIS A CE1 1 
ATOM   1595 N  NE2 . HIS A 1 202 ? 13.79284  -0.52159  -7.91325  1.000 32.55531 ? 200 HIS A NE2 1 
ATOM   1596 N  N   . HIS A 1 203 ? 19.14888  -0.88683  -3.77457  1.000 35.98663 ? 201 HIS A N   1 
ATOM   1597 C  CA  . HIS A 1 203 ? 20.39742  -1.30727  -3.15421  1.000 36.13589 ? 201 HIS A CA  1 
ATOM   1598 C  C   . HIS A 1 203 ? 20.13116  -2.11202  -1.88407  1.000 40.56889 ? 201 HIS A C   1 
ATOM   1599 O  O   . HIS A 1 203 ? 20.81740  -3.10422  -1.60782  1.000 42.70127 ? 201 HIS A O   1 
ATOM   1600 C  CB  . HIS A 1 203 ? 21.24489  -0.06867  -2.85163  1.000 38.60735 ? 201 HIS A CB  1 
ATOM   1601 C  CG  . HIS A 1 203 ? 22.50641  -0.37600  -2.11999  1.000 40.21318 ? 201 HIS A CG  1 
ATOM   1602 N  ND1 . HIS A 1 203 ? 22.58978  -0.36540  -0.74315  1.000 41.87463 ? 201 HIS A ND1 1 
ATOM   1603 C  CD2 . HIS A 1 203 ? 23.72876  -0.73613  -2.57226  1.000 38.70718 ? 201 HIS A CD2 1 
ATOM   1604 C  CE1 . HIS A 1 203 ? 23.81703  -0.69069  -0.38241  1.000 41.41376 ? 201 HIS A CE1 1 
ATOM   1605 N  NE2 . HIS A 1 203 ? 24.52472  -0.91882  -1.47420  1.000 34.79464 ? 201 HIS A NE2 1 
ATOM   1606 N  N   . LEU A 1 204 ? 19.12403  -1.70560  -1.10788  1.000 38.12571 ? 202 LEU A N   1 
ATOM   1607 C  CA  . LEU A 1 204 ? 18.76289  -2.43817  0.10192   1.000 40.92165 ? 202 LEU A CA  1 
ATOM   1608 C  C   . LEU A 1 204 ? 18.21273  -3.81746  -0.24223  1.000 44.18616 ? 202 LEU A C   1 
ATOM   1609 O  O   . LEU A 1 204 ? 18.55675  -4.81889  0.40540   1.000 42.35356 ? 202 LEU A O   1 
ATOM   1610 C  CB  . LEU A 1 204 ? 17.73298  -1.62791  0.89873   1.000 40.92950 ? 202 LEU A CB  1 
ATOM   1611 C  CG  . LEU A 1 204 ? 17.32897  -2.07929  2.31255   1.000 47.11886 ? 202 LEU A CG  1 
ATOM   1612 C  CD1 . LEU A 1 204 ? 18.54350  -2.01705  3.21127   1.000 47.19527 ? 202 LEU A CD1 1 
ATOM   1613 C  CD2 . LEU A 1 204 ? 16.19671  -1.20822  2.89411   1.000 45.82728 ? 202 LEU A CD2 1 
ATOM   1614 N  N   . ILE A 1 205 ? 17.34269  -3.88549  -1.25252  1.000 39.74863 ? 203 ILE A N   1 
ATOM   1615 C  CA  . ILE A 1 205 ? 16.76509  -5.16418  -1.64921  1.000 41.90186 ? 203 ILE A CA  1 
ATOM   1616 C  C   . ILE A 1 205 ? 17.86903  -6.11829  -2.09095  1.000 41.96916 ? 203 ILE A C   1 
ATOM   1617 O  O   . ILE A 1 205 ? 17.90596  -7.28654  -1.68297  1.000 41.87527 ? 203 ILE A O   1 
ATOM   1618 C  CB  . ILE A 1 205 ? 15.70586  -4.94302  -2.74231  1.000 40.36905 ? 203 ILE A CB  1 
ATOM   1619 C  CG1 . ILE A 1 205 ? 14.45114  -4.30321  -2.13974  1.000 41.58727 ? 203 ILE A CG1 1 
ATOM   1620 C  CG2 . ILE A 1 205 ? 15.33885  -6.23394  -3.42934  1.000 36.25198 ? 203 ILE A CG2 1 
ATOM   1621 C  CD1 . ILE A 1 205 ? 13.49460  -3.76371  -3.19567  1.000 35.76007 ? 203 ILE A CD1 1 
ATOM   1622 N  N   . MET A 1 206 ? 18.80461  -5.62273  -2.90648  1.000 41.52012 ? 204 MET A N   1 
ATOM   1623 C  CA  . MET A 1 206 ? 20.03456  -6.35862  -3.19604  1.000 41.53892 ? 204 MET A CA  1 
ATOM   1624 C  C   . MET A 1 206 ? 20.69596  -6.90648  -1.93274  1.000 43.08627 ? 204 MET A C   1 
ATOM   1625 O  O   . MET A 1 206 ? 20.95038  -8.11057  -1.82587  1.000 42.72206 ? 204 MET A O   1 
ATOM   1626 C  CB  . MET A 1 206 ? 20.99922  -5.45351  -3.94789  1.000 42.57821 ? 204 MET A CB  1 
ATOM   1627 C  CG  . MET A 1 206 ? 22.14668  -6.13530  -4.65879  1.000 43.74005 ? 204 MET A CG  1 
ATOM   1628 S  SD  . MET A 1 206 ? 23.47474  -6.09717  -3.42338  1.000 43.48174 ? 204 MET A SD  1 
ATOM   1629 C  CE  . MET A 1 206 ? 23.73806  -4.31756  -3.43660  1.000 39.81867 ? 204 MET A CE  1 
ATOM   1630 N  N   . VAL A 1 207 ? 21.00385  -6.02792  -0.97484  1.000 43.48368 ? 205 VAL A N   1 
ATOM   1631 C  CA  . VAL A 1 207 ? 21.67849  -6.47056  0.24609   1.000 45.16853 ? 205 VAL A CA  1 
ATOM   1632 C  C   . VAL A 1 207 ? 20.90565  -7.60065  0.91866   1.000 42.99722 ? 205 VAL A C   1 
ATOM   1633 O  O   . VAL A 1 207 ? 21.49905  -8.58652  1.38025   1.000 43.37822 ? 205 VAL A O   1 
ATOM   1634 C  CB  . VAL A 1 207 ? 21.89476  -5.28254  1.20121   1.000 43.61717 ? 205 VAL A CB  1 
ATOM   1635 C  CG1 . VAL A 1 207 ? 22.14118  -5.77975  2.61284   1.000 44.51463 ? 205 VAL A CG1 1 
ATOM   1636 C  CG2 . VAL A 1 207 ? 23.07289  -4.45704  0.73046   1.000 42.85072 ? 205 VAL A CG2 1 
ATOM   1637 N  N   . TRP A 1 208 ? 19.57127  -7.49912  0.95264   1.000 42.42718 ? 206 TRP A N   1 
ATOM   1638 C  CA  . TRP A 1 208 ? 18.75531  -8.54957  1.56346   1.000 41.00630 ? 206 TRP A CA  1 
ATOM   1639 C  C   . TRP A 1 208 ? 18.98028  -9.89891  0.89292   1.000 43.27620 ? 206 TRP A C   1 
ATOM   1640 O  O   . TRP A 1 208 ? 18.96569  -10.94089 1.56074   1.000 40.50507 ? 206 TRP A O   1 
ATOM   1641 C  CB  . TRP A 1 208 ? 17.26673  -8.19900  1.48560   1.000 42.49527 ? 206 TRP A CB  1 
ATOM   1642 C  CG  . TRP A 1 208 ? 16.84715  -7.02839  2.30009   1.000 45.63655 ? 206 TRP A CG  1 
ATOM   1643 C  CD1 . TRP A 1 208 ? 17.54649  -6.43645  3.31039   1.000 46.72609 ? 206 TRP A CD1 1 
ATOM   1644 C  CD2 . TRP A 1 208 ? 15.63244  -6.28033  2.16054   1.000 45.94980 ? 206 TRP A CD2 1 
ATOM   1645 N  NE1 . TRP A 1 208 ? 16.84550  -5.37756  3.81133   1.000 46.41801 ? 206 TRP A NE1 1 
ATOM   1646 C  CE2 . TRP A 1 208 ? 15.66261  -5.25778  3.12801   1.000 47.51781 ? 206 TRP A CE2 1 
ATOM   1647 C  CE3 . TRP A 1 208 ? 14.52186  -6.37712  1.31068   1.000 45.74990 ? 206 TRP A CE3 1 
ATOM   1648 C  CZ2 . TRP A 1 208 ? 14.62650  -4.32251  3.26756   1.000 50.98269 ? 206 TRP A CZ2 1 
ATOM   1649 C  CZ3 . TRP A 1 208 ? 13.48539  -5.45931  1.45747   1.000 44.05910 ? 206 TRP A CZ3 1 
ATOM   1650 C  CH2 . TRP A 1 208 ? 13.55032  -4.44032  2.42594   1.000 49.39527 ? 206 TRP A CH2 1 
ATOM   1651 N  N   . SER A 1 209 ? 19.14682  -9.90134  -0.43355  1.000 39.28096 ? 207 SER A N   1 
ATOM   1652 C  CA  . SER A 1 209 ? 19.34991  -11.11591 -1.21886  1.000 42.14876 ? 207 SER A CA  1 
ATOM   1653 C  C   . SER A 1 209 ? 20.78441  -11.61943 -1.18501  1.000 40.43847 ? 207 SER A C   1 
ATOM   1654 O  O   . SER A 1 209 ? 21.04176  -12.73588 -1.63805  1.000 44.54926 ? 207 SER A O   1 
ATOM   1655 C  CB  . SER A 1 209 ? 18.94350  -10.87019 -2.67991  1.000 43.49590 ? 207 SER A CB  1 
ATOM   1656 O  OG  . SER A 1 209 ? 20.00108  -10.24548 -3.40044  1.000 41.61142 ? 207 SER A OG  1 
ATOM   1657 N  N   . GLN A 1 210 ? 21.72224  -10.82547 -0.68917  1.000 41.69483 ? 208 GLN A N   1 
ATOM   1658 C  CA  . GLN A 1 210 ? 23.12818  -11.19018 -0.70321  1.000 41.32472 ? 208 GLN A CA  1 
ATOM   1659 C  C   . GLN A 1 210 ? 23.71018  -11.39876 0.68358   1.000 44.92505 ? 208 GLN A C   1 
ATOM   1660 O  O   . GLN A 1 210 ? 24.49752  -12.32284 0.87964   1.000 44.63213 ? 208 GLN A O   1 
ATOM   1661 C  CB  . GLN A 1 210 ? 23.93371  -10.11771 -1.45068  1.000 41.08623 ? 208 GLN A CB  1 
ATOM   1662 C  CG  . GLN A 1 210 ? 23.47656  -9.91325  -2.91367  1.000 40.29446 ? 208 GLN A CG  1 
ATOM   1663 C  CD  . GLN A 1 210 ? 24.12216  -10.93857 -3.85406  1.000 43.18234 ? 208 GLN A CD  1 
ATOM   1664 O  OE1 . GLN A 1 210 ? 25.24968  -11.35897 -3.62076  1.000 41.68147 ? 208 GLN A OE1 1 
ATOM   1665 N  NE2 . GLN A 1 210 ? 23.40615  -11.34812 -4.90943  1.000 40.85880 ? 208 GLN A NE2 1 
ATOM   1666 N  N   . LEU A 1 211 ? 23.34551  -10.56387 1.65465   1.000 44.06186 ? 209 LEU A N   1 
ATOM   1667 C  CA  . LEU A 1 211 ? 23.79978  -10.72004 3.02590   1.000 45.98721 ? 209 LEU A CA  1 
ATOM   1668 C  C   . LEU A 1 211 ? 22.70538  -11.18700 3.97119   1.000 48.55583 ? 209 LEU A C   1 
ATOM   1669 O  O   . LEU A 1 211 ? 23.01937  -11.60641 5.09068   1.000 47.97189 ? 209 LEU A O   1 
ATOM   1670 C  CB  . LEU A 1 211 ? 24.39139  -9.40373  3.54704   1.000 47.53874 ? 209 LEU A CB  1 
ATOM   1671 C  CG  . LEU A 1 211 ? 25.60740  -8.84837  2.81064   1.000 48.93078 ? 209 LEU A CG  1 
ATOM   1672 C  CD1 . LEU A 1 211 ? 26.19957  -7.67737  3.57890   1.000 49.36465 ? 209 LEU A CD1 1 
ATOM   1673 C  CD2 . LEU A 1 211 ? 26.65505  -9.93283  2.58897   1.000 48.16222 ? 209 LEU A CD2 1 
ATOM   1674 N  N   . GLY A 1 212 ? 21.44595  -11.14349 3.55407   1.000 47.66394 ? 210 GLY A N   1 
ATOM   1675 C  CA  . GLY A 1 212 ? 20.33761  -11.53991 4.39860   1.000 45.44842 ? 210 GLY A CA  1 
ATOM   1676 C  C   . GLY A 1 212 ? 19.65631  -10.35599 5.06244   1.000 48.51462 ? 210 GLY A C   1 
ATOM   1677 O  O   . GLY A 1 212 ? 19.78274  -9.19673  4.65313   1.000 45.57946 ? 210 GLY A O   1 
ATOM   1678 N  N   . GLY A 1 213 ? 18.90806  -10.66787 6.11424   1.000 49.79860 ? 211 GLY A N   1 
ATOM   1679 C  CA  . GLY A 1 213 ? 18.29345  -9.63466  6.91872   1.000 48.31234 ? 211 GLY A CA  1 
ATOM   1680 C  C   . GLY A 1 213 ? 17.03462  -9.01950  6.35089   1.000 50.13339 ? 211 GLY A C   1 
ATOM   1681 O  O   . GLY A 1 213 ? 16.67790  -7.90290  6.75015   1.000 48.59146 ? 211 GLY A O   1 
ATOM   1682 N  N   . GLN A 1 214 ? 16.35141  -9.69574  5.42773   1.000 46.66950 ? 212 GLN A N   1 
ATOM   1683 C  CA  . GLN A 1 214 ? 15.08010  -9.17580  4.95616   1.000 46.06511 ? 212 GLN A CA  1 
ATOM   1684 C  C   . GLN A 1 214 ? 14.17012  -8.98598  6.16256   1.000 49.57860 ? 212 GLN A C   1 
ATOM   1685 O  O   . GLN A 1 214 ? 14.06493  -9.89172  6.99514   1.000 51.88962 ? 212 GLN A O   1 
ATOM   1686 C  CB  . GLN A 1 214 ? 14.42732  -10.11509 3.94510   1.000 45.28832 ? 212 GLN A CB  1 
ATOM   1687 C  CG  . GLN A 1 214 ? 13.60528  -9.40094  2.88247   1.000 45.97355 ? 212 GLN A CG  1 
ATOM   1688 C  CD  . GLN A 1 214 ? 12.19561  -9.07001  3.34888   1.000 49.21597 ? 212 GLN A CD  1 
ATOM   1689 O  OE1 . GLN A 1 214 ? 11.56346  -9.85134  4.06004   1.000 50.80696 ? 212 GLN A OE1 1 
ATOM   1690 N  NE2 . GLN A 1 214 ? 11.70357  -7.89455  2.96368   1.000 48.43879 ? 212 GLN A NE2 1 
ATOM   1691 N  N   . PRO A 1 215 ? 13.52263  -7.82947  6.31033   1.000 50.40908 ? 213 PRO A N   1 
ATOM   1692 C  CA  . PRO A 1 215 ? 12.81425  -7.55506  7.56750   1.000 50.40394 ? 213 PRO A CA  1 
ATOM   1693 C  C   . PRO A 1 215 ? 11.62142  -8.45956  7.80888   1.000 53.03449 ? 213 PRO A C   1 
ATOM   1694 O  O   . PRO A 1 215 ? 11.31182  -8.74174  8.97412   1.000 53.91508 ? 213 PRO A O   1 
ATOM   1695 C  CB  . PRO A 1 215 ? 12.39572  -6.08347  7.41896   1.000 51.02650 ? 213 PRO A CB  1 
ATOM   1696 C  CG  . PRO A 1 215 ? 13.29985  -5.54398  6.37871   1.000 52.36260 ? 213 PRO A CG  1 
ATOM   1697 C  CD  . PRO A 1 215 ? 13.49794  -6.66907  5.41447   1.000 49.82926 ? 213 PRO A CD  1 
ATOM   1698 N  N   . GLY A 1 216 ? 10.95617  -8.93897  6.75169   1.000 53.68391 ? 214 GLY A N   1 
ATOM   1699 C  CA  . GLY A 1 216 ? 9.78771   -9.78844  6.93923   1.000 54.01015 ? 214 GLY A CA  1 
ATOM   1700 C  C   . GLY A 1 216 ? 10.04419  -10.95638 7.86735   1.000 57.91281 ? 214 GLY A C   1 
ATOM   1701 O  O   . GLY A 1 216 ? 9.12780   -11.43541 8.54303   1.000 63.50205 ? 214 GLY A O   1 
ATOM   1702 N  N   . LEU A 1 217 ? 11.29439  -11.41990 7.92463   1.000 57.59168 ? 215 LEU A N   1 
ATOM   1703 C  CA  . LEU A 1 217 ? 11.75727  -12.45520 8.83554   1.000 58.15477 ? 215 LEU A CA  1 
ATOM   1704 C  C   . LEU A 1 217 ? 11.81313  -11.99687 10.29331  1.000 59.74503 ? 215 LEU A C   1 
ATOM   1705 O  O   . LEU A 1 217 ? 12.17538  -12.80904 11.14870  1.000 61.84666 ? 215 LEU A O   1 
ATOM   1706 C  CB  . LEU A 1 217 ? 13.14607  -12.93246 8.38832   1.000 54.41935 ? 215 LEU A CB  1 
ATOM   1707 C  CG  . LEU A 1 217 ? 13.45244  -13.03261 6.87933   1.000 55.04247 ? 215 LEU A CG  1 
ATOM   1708 C  CD1 . LEU A 1 217 ? 14.94889  -13.17200 6.62355   1.000 49.79803 ? 215 LEU A CD1 1 
ATOM   1709 C  CD2 . LEU A 1 217 ? 12.71896  -14.20556 6.22559   1.000 51.24136 ? 215 LEU A CD2 1 
ATOM   1710 N  N   . ARG A 1 218 ? 11.45510  -10.74622 10.58518  1.000 62.66324 ? 216 ARG A N   1 
ATOM   1711 C  CA  . ARG A 1 218 ? 11.73502  -10.07570 11.86568  1.000 63.48450 ? 216 ARG A CA  1 
ATOM   1712 C  C   . ARG A 1 218 ? 13.09672  -10.44814 12.43485  1.000 62.25395 ? 216 ARG A C   1 
ATOM   1713 O  O   . ARG A 1 218 ? 14.08323  -9.74545  12.21114  1.000 62.53861 ? 216 ARG A O   1 
ATOM   1714 C  CB  . ARG A 1 218 ? 10.65039  -10.37055 12.89685  1.000 67.85153 ? 216 ARG A CB  1 
ATOM   1715 C  CG  . ARG A 1 218 ? 9.62257   -9.26882  12.99451  1.000 68.32387 ? 216 ARG A CG  1 
ATOM   1716 C  CD  . ARG A 1 218 ? 8.44551   -9.68504  13.86496  1.000 70.03325 ? 216 ARG A CD  1 
ATOM   1717 N  NE  . ARG A 1 218 ? 7.92544   -11.00298 13.51709  1.000 74.14864 ? 216 ARG A NE  1 
ATOM   1718 C  CZ  . ARG A 1 218 ? 7.51461   -11.37600 12.30977  1.000 74.41206 ? 216 ARG A CZ  1 
ATOM   1719 N  NH1 . ARG A 1 218 ? 7.50967   -10.53590 11.28223  1.000 69.84792 ? 216 ARG A NH1 1 
ATOM   1720 N  NH2 . ARG A 1 218 ? 7.09844   -12.62748 12.12657  1.000 69.74954 ? 216 ARG A NH2 1 
ATOM   1721 N  N   . GLU A 1 229 ? 19.85323  -11.30618 15.99245  1.000 60.60855 ? 227 GLU A N   1 
ATOM   1722 C  CA  . GLU A 1 229 ? 20.97769  -10.53923 15.46763  1.000 64.38427 ? 227 GLU A CA  1 
ATOM   1723 C  C   . GLU A 1 229 ? 20.98529  -10.56034 13.93847  1.000 62.56136 ? 227 GLU A C   1 
ATOM   1724 O  O   . GLU A 1 229 ? 20.56974  -11.54496 13.31136  1.000 55.25576 ? 227 GLU A O   1 
ATOM   1725 C  CB  . GLU A 1 229 ? 22.31309  -11.07432 15.99877  1.000 65.07355 ? 227 GLU A CB  1 
ATOM   1726 C  CG  . GLU A 1 229 ? 23.52263  -10.31559 15.44539  1.000 66.68589 ? 227 GLU A CG  1 
ATOM   1727 C  CD  . GLU A 1 229 ? 24.86272  -10.89267 15.87380  1.000 69.85760 ? 227 GLU A CD  1 
ATOM   1728 O  OE1 . GLU A 1 229 ? 24.96901  -12.13239 16.00886  1.000 66.54456 ? 227 GLU A OE1 1 
ATOM   1729 O  OE2 . GLU A 1 229 ? 25.81418  -10.09503 16.06238  1.000 71.33990 ? 227 GLU A OE2 1 
ATOM   1730 N  N   . LEU A 1 230 ? 21.47123  -9.43316  13.33427  1.000 60.46388 ? 228 LEU A N   1 
ATOM   1731 C  CA  . LEU A 1 230 ? 21.54229  -9.12355  11.91341  1.000 60.74031 ? 228 LEU A CA  1 
ATOM   1732 C  C   . LEU A 1 230 ? 22.94559  -9.36434  11.37090  1.000 59.75319 ? 228 LEU A C   1 
ATOM   1733 O  O   . LEU A 1 230 ? 23.92984  -9.28137  12.11296  1.000 59.84073 ? 228 LEU A O   1 
ATOM   1734 C  CB  . LEU A 1 230 ? 21.16308  -7.65825  11.65964  1.000 58.45006 ? 228 LEU A CB  1 
ATOM   1735 C  CG  . LEU A 1 230 ? 19.67320  -7.31385  11.69834  1.000 57.84913 ? 228 LEU A CG  1 
ATOM   1736 C  CD1 . LEU A 1 230 ? 19.46470  -5.84947  12.11380  1.000 57.36164 ? 228 LEU A CD1 1 
ATOM   1737 C  CD2 . LEU A 1 230 ? 18.98825  -7.62475  10.37702  1.000 61.51108 ? 228 LEU A CD2 1 
ATOM   1738 N  N   . PRO A 1 231 ? 23.05670  -9.66296  10.07552  1.000 58.36283 ? 229 PRO A N   1 
ATOM   1739 C  CA  . PRO A 1 231 ? 24.36425  -9.63086  9.41189   1.000 55.19078 ? 229 PRO A CA  1 
ATOM   1740 C  C   . PRO A 1 231 ? 25.02438  -8.26363  9.54767   1.000 59.92668 ? 229 PRO A C   1 
ATOM   1741 O  O   . PRO A 1 231 ? 24.41715  -7.26883  9.95913   1.000 58.42431 ? 229 PRO A O   1 
ATOM   1742 C  CB  . PRO A 1 231 ? 24.02447  -9.94643  7.95367   1.000 54.07847 ? 229 PRO A CB  1 
ATOM   1743 C  CG  . PRO A 1 231 ? 22.76577  -10.74659 8.03470   1.000 52.68468 ? 229 PRO A CG  1 
ATOM   1744 C  CD  . PRO A 1 231 ? 21.99856  -10.18602 9.19295   1.000 55.45179 ? 229 PRO A CD  1 
ATOM   1745 N  N   . GLN A 1 232 ? 26.30535  -8.22091  9.18659   1.000 60.08365 ? 230 GLN A N   1 
ATOM   1746 C  CA  . GLN A 1 232 ? 27.10688  -7.01884  9.34439   1.000 60.48666 ? 230 GLN A CA  1 
ATOM   1747 C  C   . GLN A 1 232 ? 27.87092  -6.70789  8.06824   1.000 61.44370 ? 230 GLN A C   1 
ATOM   1748 O  O   . GLN A 1 232 ? 28.29915  -7.60889  7.34204   1.000 60.99041 ? 230 GLN A O   1 
ATOM   1749 C  CB  . GLN A 1 232 ? 28.10725  -7.14930  10.49032  1.000 62.17320 ? 230 GLN A CB  1 
ATOM   1750 C  CG  . GLN A 1 232 ? 27.51399  -7.70411  11.76404  1.000 65.16896 ? 230 GLN A CG  1 
ATOM   1751 C  CD  . GLN A 1 232 ? 28.54566  -7.88081  12.85963  1.000 69.75578 ? 230 GLN A CD  1 
ATOM   1752 O  OE1 . GLN A 1 232 ? 29.75452  -7.85331  12.60246  1.000 68.20480 ? 230 GLN A OE1 1 
ATOM   1753 N  NE2 . GLN A 1 232 ? 28.07406  -8.08508  14.09044  1.000 68.97507 ? 230 GLN A NE2 1 
ATOM   1754 N  N   . SER A 1 233 ? 28.05378  -5.41161  7.82362   1.000 60.61887 ? 231 SER A N   1 
ATOM   1755 C  CA  . SER A 1 233 ? 28.88446  -4.92608  6.73649   1.000 58.65069 ? 231 SER A CA  1 
ATOM   1756 C  C   . SER A 1 233 ? 30.34137  -5.35410  6.93667   1.000 60.16458 ? 231 SER A C   1 
ATOM   1757 O  O   . SER A 1 233 ? 30.72264  -5.91672  7.96350   1.000 60.97757 ? 231 SER A O   1 
ATOM   1758 C  CB  . SER A 1 233 ? 28.77953  -3.40001  6.64811   1.000 60.65281 ? 231 SER A CB  1 
ATOM   1759 O  OG  . SER A 1 233 ? 29.65446  -2.76738  7.56958   1.000 57.09389 ? 231 SER A OG  1 
ATOM   1760 N  N   . LEU A 1 234 ? 31.16208  -5.07316  5.92837   1.000 58.90488 ? 232 LEU A N   1 
ATOM   1761 C  CA  . LEU A 1 234 ? 32.61352  -5.27592  5.99031   1.000 60.30393 ? 232 LEU A CA  1 
ATOM   1762 C  C   . LEU A 1 234 ? 33.31944  -4.29097  6.95635   1.000 60.80323 ? 232 LEU A C   1 
ATOM   1763 O  O   . LEU A 1 234 ? 34.55880  -4.26834  7.02222   1.000 58.21092 ? 232 LEU A O   1 
ATOM   1764 C  CB  . LEU A 1 234 ? 33.21701  -5.15599  4.58857   1.000 56.97899 ? 232 LEU A CB  1 
ATOM   1765 C  CG  . LEU A 1 234 ? 33.00350  -6.37119  3.68277   1.000 56.99556 ? 232 LEU A CG  1 
ATOM   1766 C  CD1 . LEU A 1 234 ? 33.80428  -6.22822  2.38969   1.000 57.46337 ? 232 LEU A CD1 1 
ATOM   1767 C  CD2 . LEU A 1 234 ? 33.37279  -7.65420  4.41098   1.000 56.78340 ? 232 LEU A CD2 1 
ATOM   1768 N  N   . GLY A 1 235 ? 32.52773  -3.49272  7.67263   1.000 61.31323 ? 233 GLY A N   1 
ATOM   1769 C  CA  . GLY A 1 235 ? 33.02275  -2.57330  8.67606   1.000 62.59775 ? 233 GLY A CA  1 
ATOM   1770 C  C   . GLY A 1 235 ? 32.43788  -2.89449  10.03589  1.000 63.87389 ? 233 GLY A C   1 
ATOM   1771 O  O   . GLY A 1 235 ? 32.61479  -2.13625  10.99689  1.000 63.62011 ? 233 GLY A O   1 
ATOM   1772 N  N   . GLY A 1 236 ? 31.72169  -4.01676  10.11332  1.000 62.31436 ? 234 GLY A N   1 
ATOM   1773 C  CA  . GLY A 1 236 ? 31.17730  -4.52167  11.35759  1.000 61.08827 ? 234 GLY A CA  1 
ATOM   1774 C  C   . GLY A 1 236 ? 29.82213  -3.98382  11.76464  1.000 65.29361 ? 234 GLY A C   1 
ATOM   1775 O  O   . GLY A 1 236 ? 29.34561  -4.32781  12.85557  1.000 65.94569 ? 234 GLY A O   1 
ATOM   1776 N  N   . ARG A 1 237 ? 29.17882  -3.16524  10.93142  1.000 62.43172 ? 235 ARG A N   1 
ATOM   1777 C  CA  . ARG A 1 237 ? 27.94026  -2.48567  11.30006  1.000 62.37259 ? 235 ARG A CA  1 
ATOM   1778 C  C   . ARG A 1 237 ? 26.71978  -3.29089  10.86763  1.000 60.52549 ? 235 ARG A C   1 
ATOM   1779 O  O   . ARG A 1 237 ? 26.71936  -3.92873  9.81220   1.000 61.02883 ? 235 ARG A O   1 
ATOM   1780 C  CB  . ARG A 1 237 ? 27.88119  -1.07785  10.69034  1.000 60.66252 ? 235 ARG A CB  1 
ATOM   1781 C  CG  . ARG A 1 237 ? 29.01782  -0.15286  11.13675  1.000 61.55178 ? 235 ARG A CG  1 
ATOM   1782 C  CD  . ARG A 1 237 ? 29.15634  1.09457   10.24909  1.000 64.34306 ? 235 ARG A CD  1 
ATOM   1783 N  NE  . ARG A 1 237 ? 29.90510  0.80314   9.03234   1.000 61.64923 ? 235 ARG A NE  1 
ATOM   1784 C  CZ  . ARG A 1 237 ? 31.13243  1.24260   8.79185   1.000 63.57663 ? 235 ARG A CZ  1 
ATOM   1785 N  NH1 . ARG A 1 237 ? 31.76908  2.01704   9.65582   1.000 61.49443 ? 235 ARG A NH1 1 
ATOM   1786 N  NH2 . ARG A 1 237 ? 31.74105  0.88734   7.66092   1.000 62.82905 ? 235 ARG A NH2 1 
ATOM   1787 N  N   . SER A 1 238 ? 25.67765  -3.24349  11.68924  1.000 61.79045 ? 236 SER A N   1 
ATOM   1788 C  CA  . SER A 1 238 ? 24.45692  -3.97697  11.40499  1.000 60.52595 ? 236 SER A CA  1 
ATOM   1789 C  C   . SER A 1 238 ? 23.75926  -3.40023  10.18036  1.000 56.59869 ? 236 SER A C   1 
ATOM   1790 O  O   . SER A 1 238 ? 23.86330  -2.20887  9.87820   1.000 57.36997 ? 236 SER A O   1 
ATOM   1791 C  CB  . SER A 1 238 ? 23.51779  -3.94125  12.61417  1.000 57.71811 ? 236 SER A CB  1 
ATOM   1792 O  OG  . SER A 1 238 ? 22.15768  -4.09254  12.24077  1.000 57.95628 ? 236 SER A OG  1 
ATOM   1793 N  N   . LEU A 1 239 ? 23.04277  -4.27668  9.47434   1.000 55.21295 ? 237 LEU A N   1 
ATOM   1794 C  CA  . LEU A 1 239 ? 22.25749  -3.88351  8.31349   1.000 53.34203 ? 237 LEU A CA  1 
ATOM   1795 C  C   . LEU A 1 239 ? 21.11706  -2.94095  8.67292   1.000 54.29097 ? 237 LEU A C   1 
ATOM   1796 O  O   . LEU A 1 239 ? 20.53994  -2.31772  7.77500   1.000 51.21554 ? 237 LEU A O   1 
ATOM   1797 C  CB  . LEU A 1 239 ? 21.70240  -5.13358  7.63314   1.000 57.29026 ? 237 LEU A CB  1 
ATOM   1798 C  CG  . LEU A 1 239 ? 22.75693  -6.06875  7.04244   1.000 55.55289 ? 237 LEU A CG  1 
ATOM   1799 C  CD1 . LEU A 1 239 ? 22.10079  -7.06368  6.10154   1.000 55.27904 ? 237 LEU A CD1 1 
ATOM   1800 C  CD2 . LEU A 1 239 ? 23.83367  -5.26799  6.31478   1.000 56.42909 ? 237 LEU A CD2 1 
ATOM   1801 N  N   . ALA A 1 240 ? 20.76708  -2.82902  9.95842   1.000 52.85305 ? 238 ALA A N   1 
ATOM   1802 C  CA  . ALA A 1 240 ? 19.71683  -1.89186  10.34616  1.000 53.34715 ? 238 ALA A CA  1 
ATOM   1803 C  C   . ALA A 1 240 ? 20.16557  -0.44066  10.18511  1.000 51.71737 ? 238 ALA A C   1 
ATOM   1804 O  O   . ALA A 1 240 ? 19.33324  0.44294   9.94719   1.000 49.16361 ? 238 ALA A O   1 
ATOM   1805 C  CB  . ALA A 1 240 ? 19.27032  -2.16460  11.78713  1.000 51.69562 ? 238 ALA A CB  1 
ATOM   1806 N  N   . THR A 1 241 ? 21.46311  -0.16674  10.31814  1.000 48.75700 ? 239 THR A N   1 
ATOM   1807 C  CA  . THR A 1 241 ? 21.92728  1.18435   10.05836  1.000 53.20391 ? 239 THR A CA  1 
ATOM   1808 C  C   . THR A 1 241 ? 21.77898  1.52332   8.58501   1.000 52.92040 ? 239 THR A C   1 
ATOM   1809 O  O   . THR A 1 241 ? 21.38643  2.64384   8.23840   1.000 48.53410 ? 239 THR A O   1 
ATOM   1810 C  CB  . THR A 1 241 ? 23.37560  1.35195   10.51264  1.000 56.61482 ? 239 THR A CB  1 
ATOM   1811 O  OG1 . THR A 1 241 ? 24.21151  0.46174   9.76392   1.000 62.97323 ? 239 THR A OG1 1 
ATOM   1812 C  CG2 . THR A 1 241 ? 23.51107  1.06651   12.00440  1.000 56.29724 ? 239 THR A CG2 1 
ATOM   1813 N  N   . LEU A 1 242 ? 22.05974  0.55570   7.70617   1.000 50.41086 ? 240 LEU A N   1 
ATOM   1814 C  CA  . LEU A 1 242 ? 21.83931  0.77260   6.28333   1.000 48.96962 ? 240 LEU A CA  1 
ATOM   1815 C  C   . LEU A 1 242 ? 20.37449  1.08299   6.01163   1.000 48.90972 ? 240 LEU A C   1 
ATOM   1816 O  O   . LEU A 1 242 ? 20.05030  2.03000   5.27906   1.000 45.21840 ? 240 LEU A O   1 
ATOM   1817 C  CB  . LEU A 1 242 ? 22.28625  -0.45081  5.48395   1.000 43.78020 ? 240 LEU A CB  1 
ATOM   1818 C  CG  . LEU A 1 242 ? 22.04532  -0.33867  3.97794   1.000 43.36752 ? 240 LEU A CG  1 
ATOM   1819 C  CD1 . LEU A 1 242 ? 22.89308  0.80393   3.36442   1.000 42.18650 ? 240 LEU A CD1 1 
ATOM   1820 C  CD2 . LEU A 1 242 ? 22.31330  -1.66308  3.26452   1.000 37.75582 ? 240 LEU A CD2 1 
ATOM   1821 N  N   . GLU A 1 243 ? 19.47620  0.29804   6.61161   1.000 44.67093 ? 241 GLU A N   1 
ATOM   1822 C  CA  . GLU A 1 243 ? 18.05161  0.47828   6.37582   1.000 46.47434 ? 241 GLU A CA  1 
ATOM   1823 C  C   . GLU A 1 243 ? 17.58894  1.85454   6.82766   1.000 51.22163 ? 241 GLU A C   1 
ATOM   1824 O  O   . GLU A 1 243 ? 16.68055  2.43508   6.22152   1.000 50.66319 ? 241 GLU A O   1 
ATOM   1825 C  CB  . GLU A 1 243 ? 17.25291  -0.60923  7.09556   1.000 45.52630 ? 241 GLU A CB  1 
ATOM   1826 C  CG  . GLU A 1 243 ? 15.74002  -0.38845  7.03992   1.000 52.26037 ? 241 GLU A CG  1 
ATOM   1827 C  CD  . GLU A 1 243 ? 14.91401  -1.60222  7.44122   1.000 57.61768 ? 241 GLU A CD  1 
ATOM   1828 O  OE1 . GLU A 1 243 ? 15.49370  -2.66520  7.77384   1.000 55.04412 ? 241 GLU A OE1 1 
ATOM   1829 O  OE2 . GLU A 1 243 ? 13.66525  -1.48147  7.43537   1.000 61.60040 ? 241 GLU A OE2 1 
ATOM   1830 N  N   . ALA A 1 244 ? 18.20464  2.39501   7.88277   1.000 50.69106 ? 242 ALA A N   1 
ATOM   1831 C  CA  . ALA A 1 244 ? 17.78088  3.69576   8.39088   1.000 52.55419 ? 242 ALA A CA  1 
ATOM   1832 C  C   . ALA A 1 244 ? 18.25588  4.82154   7.48300   1.000 50.93451 ? 242 ALA A C   1 
ATOM   1833 O  O   . ALA A 1 244 ? 17.49122  5.74599   7.18006   1.000 51.29910 ? 242 ALA A O   1 
ATOM   1834 C  CB  . ALA A 1 244 ? 18.28730  3.89206   9.81939   1.000 51.39099 ? 242 ALA A CB  1 
ATOM   1835 N  N   . ARG A 1 245 ? 19.50792  4.75603   7.02280   1.000 48.36529 ? 243 ARG A N   1 
ATOM   1836 C  CA  . ARG A 1 245 ? 19.99774  5.75106   6.07772   1.000 49.02002 ? 243 ARG A CA  1 
ATOM   1837 C  C   . ARG A 1 245 ? 19.30849  5.66166   4.72723   1.000 49.08817 ? 243 ARG A C   1 
ATOM   1838 O  O   . ARG A 1 245 ? 19.42230  6.59648   3.92884   1.000 50.40372 ? 243 ARG A O   1 
ATOM   1839 C  CB  . ARG A 1 245 ? 21.50282  5.59980   5.89480   1.000 49.45631 ? 243 ARG A CB  1 
ATOM   1840 C  CG  . ARG A 1 245 ? 22.29459  6.13194   7.05673   1.000 53.44121 ? 243 ARG A CG  1 
ATOM   1841 C  CD  . ARG A 1 245 ? 23.76169  6.23522   6.71831   1.000 55.29353 ? 243 ARG A CD  1 
ATOM   1842 N  NE  . ARG A 1 245 ? 24.24466  4.97603   6.17241   1.000 56.78214 ? 243 ARG A NE  1 
ATOM   1843 C  CZ  . ARG A 1 245 ? 24.75466  3.99972   6.91033   1.000 59.08313 ? 243 ARG A CZ  1 
ATOM   1844 N  NH1 . ARG A 1 245 ? 24.87027  4.11853   8.22363   1.000 58.61103 ? 243 ARG A NH1 1 
ATOM   1845 N  NH2 . ARG A 1 245 ? 25.14736  2.87230   6.31764   1.000 55.15610 ? 243 ARG A NH2 1 
ATOM   1846 N  N   . SER A 1 246 ? 18.59479  4.56942   4.46270   1.000 47.49595 ? 244 SER A N   1 
ATOM   1847 C  CA  . SER A 1 246 ? 17.99492  4.34086   3.15785   1.000 45.64044 ? 244 SER A CA  1 
ATOM   1848 C  C   . SER A 1 246 ? 16.81512  5.26530   2.88790   1.000 48.47264 ? 244 SER A C   1 
ATOM   1849 O  O   . SER A 1 246 ? 16.43985  5.45032   1.72648   1.000 46.93295 ? 244 SER A O   1 
ATOM   1850 C  CB  . SER A 1 246 ? 17.59417  2.85998   3.04033   1.000 46.53832 ? 244 SER A CB  1 
ATOM   1851 O  OG  . SER A 1 246 ? 16.34749  2.56800   3.65947   1.000 47.49968 ? 244 SER A OG  1 
ATOM   1852 N  N   . GLN A 1 247 ? 16.24224  5.88494   3.91097   1.000 43.28136 ? 245 GLN A N   1 
ATOM   1853 C  CA  . GLN A 1 247 ? 15.05559  6.69094   3.69445   1.000 47.60978 ? 245 GLN A CA  1 
ATOM   1854 C  C   . GLN A 1 247 ? 15.34702  8.19168   3.79793   1.000 44.92694 ? 245 GLN A C   1 
ATOM   1855 O  O   . GLN A 1 247 ? 14.43034  9.01043   3.65660   1.000 44.23984 ? 245 GLN A O   1 
ATOM   1856 C  CB  . GLN A 1 247 ? 13.97121  6.21604   4.66804   1.000 52.24051 ? 245 GLN A CB  1 
ATOM   1857 C  CG  . GLN A 1 247 ? 13.09565  5.13637   3.99718   1.000 51.26341 ? 245 GLN A CG  1 
ATOM   1858 C  CD  . GLN A 1 247 ? 12.13603  4.42794   4.94202   1.000 58.81523 ? 245 GLN A CD  1 
ATOM   1859 O  OE1 . GLN A 1 247 ? 11.26609  3.65865   4.50446   1.000 59.86603 ? 245 GLN A OE1 1 
ATOM   1860 N  NE2 . GLN A 1 247 ? 12.27923  4.68660   6.24253   1.000 57.17277 ? 245 GLN A NE2 1 
ATOM   1861 N  N   . LEU A 1 248 ? 16.61502  8.56559   3.98107   1.000 43.14881 ? 246 LEU A N   1 
ATOM   1862 C  CA  . LEU A 1 248 ? 17.03987  9.96016   3.99980   1.000 44.92780 ? 246 LEU A CA  1 
ATOM   1863 C  C   . LEU A 1 248 ? 16.98148  10.54430  2.58661   1.000 47.80798 ? 246 LEU A C   1 
ATOM   1864 O  O   . LEU A 1 248 ? 17.59286  10.00236  1.65746   1.000 43.72268 ? 246 LEU A O   1 
ATOM   1865 C  CB  . LEU A 1 248 ? 18.45884  10.04711  4.55601   1.000 45.38404 ? 246 LEU A CB  1 
ATOM   1866 C  CG  . LEU A 1 248 ? 18.65554  9.44099   5.94934   1.000 51.11650 ? 246 LEU A CG  1 
ATOM   1867 C  CD1 . LEU A 1 248 ? 20.06753  9.66691   6.46785   1.000 48.93978 ? 246 LEU A CD1 1 
ATOM   1868 C  CD2 . LEU A 1 248 ? 17.63224  10.05624  6.89524   1.000 52.00798 ? 246 LEU A CD2 1 
ATOM   1869 N  N   . ALA A 1 249 ? 16.25008  11.64455  2.42434   1.000 45.09728 ? 247 ALA A N   1 
ATOM   1870 C  CA  . ALA A 1 249 ? 16.08764  12.28260  1.12938   1.000 42.68308 ? 247 ALA A CA  1 
ATOM   1871 C  C   . ALA A 1 249 ? 17.19334  13.29961  0.88351   1.000 42.00230 ? 247 ALA A C   1 
ATOM   1872 O  O   . ALA A 1 249 ? 17.87669  13.75257  1.80686   1.000 41.73689 ? 247 ALA A O   1 
ATOM   1873 C  CB  . ALA A 1 249 ? 14.72781  12.97470  1.03225   1.000 43.34976 ? 247 ALA A CB  1 
ATOM   1874 N  N   . LEU A 1 250 ? 17.35132  13.66512  -0.39254  1.000 39.72933 ? 248 LEU A N   1 
ATOM   1875 C  CA  . LEU A 1 250 ? 18.23290  14.77532  -0.74290  1.000 39.51943 ? 248 LEU A CA  1 
ATOM   1876 C  C   . LEU A 1 250 ? 17.62623  16.10608  -0.33161  1.000 41.45707 ? 248 LEU A C   1 
ATOM   1877 O  O   . LEU A 1 250 ? 18.33593  17.00117  0.14090   1.000 42.03149 ? 248 LEU A O   1 
ATOM   1878 C  CB  . LEU A 1 250 ? 18.50584  14.80294  -2.24869  1.000 38.30550 ? 248 LEU A CB  1 
ATOM   1879 C  CG  . LEU A 1 250 ? 19.26334  13.66369  -2.93662  1.000 41.91422 ? 248 LEU A CG  1 
ATOM   1880 C  CD1 . LEU A 1 250 ? 19.34793  13.96210  -4.45274  1.000 36.62396 ? 248 LEU A CD1 1 
ATOM   1881 C  CD2 . LEU A 1 250 ? 20.66252  13.44864  -2.32809  1.000 40.09977 ? 248 LEU A CD2 1 
ATOM   1882 N  N   . PHE A 1 251 ? 16.31795  16.26199  -0.54290  1.000 38.56099 ? 249 PHE A N   1 
ATOM   1883 C  CA  . PHE A 1 251 ? 15.60665  17.52320  -0.36970  1.000 39.26931 ? 249 PHE A CA  1 
ATOM   1884 C  C   . PHE A 1 251 ? 14.47176  17.33372  0.63455   1.000 37.86962 ? 249 PHE A C   1 
ATOM   1885 O  O   . PHE A 1 251 ? 13.29235  17.33397  0.25787   1.000 39.08192 ? 249 PHE A O   1 
ATOM   1886 C  CB  . PHE A 1 251 ? 15.05046  18.02545  -1.70208  1.000 37.55077 ? 249 PHE A CB  1 
ATOM   1887 C  CG  . PHE A 1 251 ? 16.03564  18.00481  -2.83318  1.000 35.20821 ? 249 PHE A CG  1 
ATOM   1888 C  CD1 . PHE A 1 251 ? 17.28727  18.60540  -2.70877  1.000 33.42375 ? 249 PHE A CD1 1 
ATOM   1889 C  CD2 . PHE A 1 251 ? 15.70273  17.40551  -4.04265  1.000 36.34992 ? 249 PHE A CD2 1 
ATOM   1890 C  CE1 . PHE A 1 251 ? 18.18357  18.59290  -3.76212  1.000 36.47304 ? 249 PHE A CE1 1 
ATOM   1891 C  CE2 . PHE A 1 251 ? 16.59450  17.38216  -5.09522  1.000 35.37809 ? 249 PHE A CE2 1 
ATOM   1892 C  CZ  . PHE A 1 251 ? 17.83658  17.98960  -4.96498  1.000 33.68716 ? 249 PHE A CZ  1 
ATOM   1893 N  N   . PRO A 1 252 ? 14.79063  17.17645  1.91973   1.000 39.06059 ? 250 PRO A N   1 
ATOM   1894 C  CA  . PRO A 1 252 ? 13.72366  16.94902  2.92709   1.000 39.56584 ? 250 PRO A CA  1 
ATOM   1895 C  C   . PRO A 1 252 ? 12.56826  17.94054  2.83975   1.000 40.80018 ? 250 PRO A C   1 
ATOM   1896 O  O   . PRO A 1 252 ? 11.39467  17.56427  2.96664   1.000 39.20987 ? 250 PRO A O   1 
ATOM   1897 C  CB  . PRO A 1 252 ? 14.46858  17.09376  4.26014   1.000 42.74296 ? 250 PRO A CB  1 
ATOM   1898 C  CG  . PRO A 1 252 ? 15.90371  16.80881  3.94541   1.000 45.26417 ? 250 PRO A CG  1 
ATOM   1899 C  CD  . PRO A 1 252 ? 16.14061  17.21211  2.50842   1.000 41.53278 ? 250 PRO A CD  1 
ATOM   1900 N  N   . GLU A 1 253 ? 12.88806  19.20328  2.56604   1.000 36.44820 ? 251 GLU A N   1 
ATOM   1901 C  CA  . GLU A 1 253 ? 11.89939  20.27743  2.56076   1.000 39.31815 ? 251 GLU A CA  1 
ATOM   1902 C  C   . GLU A 1 253 ? 10.78908  20.05028  1.54216   1.000 38.92904 ? 251 GLU A C   1 
ATOM   1903 O  O   . GLU A 1 253 ? 9.65220   20.48095  1.76597   1.000 33.70617 ? 251 GLU A O   1 
ATOM   1904 C  CB  . GLU A 1 253 ? 12.61122  21.58414  2.25233   1.000 39.35196 ? 251 GLU A CB  1 
ATOM   1905 C  CG  . GLU A 1 253 ? 13.57015  22.01809  3.32016   1.000 40.89246 ? 251 GLU A CG  1 
ATOM   1906 C  CD  . GLU A 1 253 ? 14.98983  21.50704  3.10215   1.000 45.83540 ? 251 GLU A CD  1 
ATOM   1907 O  OE1 . GLU A 1 253 ? 15.24721  20.65566  2.19008   1.000 45.55826 ? 251 GLU A OE1 1 
ATOM   1908 O  OE2 . GLU A 1 253 ? 15.88337  22.03005  3.80860   1.000 51.49910 ? 251 GLU A OE2 1 
ATOM   1909 N  N   . LEU A 1 254 ? 11.09982  19.41002  0.40085   1.000 40.29913 ? 252 LEU A N   1 
ATOM   1910 C  CA  . LEU A 1 254 ? 10.05230  19.11756  -0.57470  1.000 36.03969 ? 252 LEU A CA  1 
ATOM   1911 C  C   . LEU A 1 254 ? 9.07344   18.09145  -0.03127  1.000 35.58405 ? 252 LEU A C   1 
ATOM   1912 O  O   . LEU A 1 254 ? 7.86923   18.17619  -0.29299  1.000 34.84703 ? 252 LEU A O   1 
ATOM   1913 C  CB  . LEU A 1 254 ? 10.65204  18.61445  -1.89603  1.000 35.03323 ? 252 LEU A CB  1 
ATOM   1914 C  CG  . LEU A 1 254 ? 11.24500  19.68744  -2.79951  1.000 39.69360 ? 252 LEU A CG  1 
ATOM   1915 C  CD1 . LEU A 1 254 ? 11.61717  19.07267  -4.16535  1.000 41.20831 ? 252 LEU A CD1 1 
ATOM   1916 C  CD2 . LEU A 1 254 ? 10.26376  20.85315  -2.94427  1.000 34.89775 ? 252 LEU A CD2 1 
ATOM   1917 N  N   . TRP A 1 255 ? 9.58123   17.08826  0.69154   1.000 35.26368 ? 253 TRP A N   1 
ATOM   1918 C  CA  . TRP A 1 255 ? 8.70980   16.07209  1.26808   1.000 34.97982 ? 253 TRP A CA  1 
ATOM   1919 C  C   . TRP A 1 255 ? 7.93404   16.62605  2.46447   1.000 35.27035 ? 253 TRP A C   1 
ATOM   1920 O  O   . TRP A 1 255 ? 6.79484   16.21524  2.71586   1.000 36.45260 ? 253 TRP A O   1 
ATOM   1921 C  CB  . TRP A 1 255 ? 9.54575   14.83510  1.65205   1.000 38.15130 ? 253 TRP A CB  1 
ATOM   1922 C  CG  . TRP A 1 255 ? 10.32703  14.29767  0.47342   1.000 34.40864 ? 253 TRP A CG  1 
ATOM   1923 C  CD1 . TRP A 1 255 ? 11.60903  14.61438  0.12727   1.000 34.75573 ? 253 TRP A CD1 1 
ATOM   1924 C  CD2 . TRP A 1 255 ? 9.85441   13.38057  -0.52274  1.000 37.11575 ? 253 TRP A CD2 1 
ATOM   1925 N  NE1 . TRP A 1 255 ? 11.97823  13.94382  -1.03292  1.000 36.70540 ? 253 TRP A NE1 1 
ATOM   1926 C  CE2 . TRP A 1 255 ? 10.91349  13.18241  -1.44937  1.000 36.97529 ? 253 TRP A CE2 1 
ATOM   1927 C  CE3 . TRP A 1 255 ? 8.64350   12.70096  -0.71811  1.000 35.98277 ? 253 TRP A CE3 1 
ATOM   1928 C  CZ2 . TRP A 1 255 ? 10.79125  12.33845  -2.54862  1.000 34.72647 ? 253 TRP A CZ2 1 
ATOM   1929 C  CZ3 . TRP A 1 255 ? 8.52420   11.85796  -1.81370  1.000 34.98686 ? 253 TRP A CZ3 1 
ATOM   1930 C  CH2 . TRP A 1 255 ? 9.59064   11.69039  -2.71385  1.000 36.71032 ? 253 TRP A CH2 1 
ATOM   1931 N  N   . ARG A 1 256 ? 8.51300   17.57506  3.19270   1.000 39.12784 ? 254 ARG A N   1 
ATOM   1932 C  CA  . ARG A 1 256 ? 7.73667   18.27826  4.21617   1.000 36.65843 ? 254 ARG A CA  1 
ATOM   1933 C  C   . ARG A 1 256 ? 6.62773   19.12407  3.59264   1.000 36.86953 ? 254 ARG A C   1 
ATOM   1934 O  O   . ARG A 1 256 ? 5.50559   19.17038  4.11193   1.000 36.48455 ? 254 ARG A O   1 
ATOM   1935 C  CB  . ARG A 1 256 ? 8.66017   19.13646  5.06792   1.000 41.67969 ? 254 ARG A CB  1 
ATOM   1936 C  CG  . ARG A 1 256 ? 8.04529   19.57199  6.41315   1.000 50.91905 ? 254 ARG A CG  1 
ATOM   1937 C  CD  . ARG A 1 256 ? 9.12930   19.72394  7.47260   1.000 56.36000 ? 254 ARG A CD  1 
ATOM   1938 N  NE  . ARG A 1 256 ? 10.46025  19.70849  6.87214   1.000 61.09313 ? 254 ARG A NE  1 
ATOM   1939 C  CZ  . ARG A 1 256 ? 11.54980  19.22428  7.45533   1.000 61.57786 ? 254 ARG A CZ  1 
ATOM   1940 N  NH1 . ARG A 1 256 ? 11.49309  18.61582  8.62943   1.000 62.64271 ? 254 ARG A NH1 1 
ATOM   1941 N  NH2 . ARG A 1 256 ? 12.72341  19.33564  6.83348   1.000 57.08483 ? 254 ARG A NH2 1 
ATOM   1942 N  N   . ALA A 1 257 ? 6.91665   19.78513  2.46740   1.000 34.93332 ? 255 ALA A N   1 
ATOM   1943 C  CA  . ALA A 1 257 ? 5.90283   20.60857  1.82140   1.000 32.69915 ? 255 ALA A CA  1 
ATOM   1944 C  C   . ALA A 1 257 ? 4.76074   19.76247  1.28722   1.000 34.08945 ? 255 ALA A C   1 
ATOM   1945 O  O   . ALA A 1 257 ? 3.60477   20.20006  1.30669   1.000 32.39125 ? 255 ALA A O   1 
ATOM   1946 C  CB  . ALA A 1 257 ? 6.53571   21.44149  0.70244   1.000 31.86923 ? 255 ALA A CB  1 
ATOM   1947 N  N   . ALA A 1 258 ? 5.06585   18.55135  0.78017   1.000 31.50619 ? 256 ALA A N   1 
ATOM   1948 C  CA  . ALA A 1 258 ? 3.99914   17.62711  0.40363   1.000 34.33327 ? 256 ALA A CA  1 
ATOM   1949 C  C   . ALA A 1 258 ? 3.13625   17.26906  1.60830   1.000 32.45460 ? 256 ALA A C   1 
ATOM   1950 O  O   . ALA A 1 258 ? 1.90201   17.21702  1.52168   1.000 30.81865 ? 256 ALA A O   1 
ATOM   1951 C  CB  . ALA A 1 258 ? 4.59629   16.35522  -0.21238  1.000 33.74923 ? 256 ALA A CB  1 
ATOM   1952 N  N   . GLU A 1 259 ? 3.77069   16.96740  2.72870   1.000 32.62927 ? 257 GLU A N   1 
ATOM   1953 C  CA  . GLU A 1 259 ? 2.99757   16.69869  3.93355   1.000 36.54797 ? 257 GLU A CA  1 
ATOM   1954 C  C   . GLU A 1 259 ? 2.16008   17.91400  4.33237   1.000 36.01348 ? 257 GLU A C   1 
ATOM   1955 O  O   . GLU A 1 259 ? 0.97261   17.77513  4.66696   1.000 35.96043 ? 257 GLU A O   1 
ATOM   1956 C  CB  . GLU A 1 259 ? 3.94086   16.26335  5.05060   1.000 39.73082 ? 257 GLU A CB  1 
ATOM   1957 C  CG  . GLU A 1 259 ? 3.35932   16.33032  6.44058   1.000 44.91589 ? 257 GLU A CG  1 
ATOM   1958 C  CD  . GLU A 1 259 ? 3.51076   15.02278  7.19921   1.000 51.56215 ? 257 GLU A CD  1 
ATOM   1959 O  OE1 . GLU A 1 259 ? 4.51007   14.30500  6.96389   1.000 50.30862 ? 257 GLU A OE1 1 
ATOM   1960 O  OE2 . GLU A 1 259 ? 2.64545   14.73742  8.06305   1.000 56.95195 ? 257 GLU A OE2 1 
ATOM   1961 N  N   . ASP A 1 260 ? 2.74924   19.11731  4.27309   1.000 32.97756 ? 258 ASP A N   1 
ATOM   1962 C  CA  . ASP A 1 260 ? 1.99183   20.32995  4.60504   1.000 35.57795 ? 258 ASP A CA  1 
ATOM   1963 C  C   . ASP A 1 260 ? 0.78414   20.50390  3.69066   1.000 36.22095 ? 258 ASP A C   1 
ATOM   1964 O  O   . ASP A 1 260 ? -0.27001  20.96358  4.12869   1.000 34.82587 ? 258 ASP A O   1 
ATOM   1965 C  CB  . ASP A 1 260 ? 2.89677   21.55351  4.51939   1.000 35.36204 ? 258 ASP A CB  1 
ATOM   1966 C  CG  . ASP A 1 260 ? 3.89051   21.62080  5.65137   1.000 37.46073 ? 258 ASP A CG  1 
ATOM   1967 O  OD1 . ASP A 1 260 ? 3.69605   20.91420  6.65687   1.000 45.58142 ? 258 ASP A OD1 1 
ATOM   1968 O  OD2 . ASP A 1 260 ? 4.87588   22.36578  5.53757   1.000 45.35028 ? 258 ASP A OD2 1 
ATOM   1969 N  N   . ALA A 1 261 ? 0.90789   20.11455  2.41609   1.000 34.10835 ? 259 ALA A N   1 
ATOM   1970 C  CA  . ALA A 1 261 ? -0.20596  20.28448  1.48339   1.000 32.50228 ? 259 ALA A CA  1 
ATOM   1971 C  C   . ALA A 1 261 ? -1.36249  19.35477  1.81469   1.000 34.51520 ? 259 ALA A C   1 
ATOM   1972 O  O   . ALA A 1 261 ? -2.53123  19.73999  1.69783   1.000 34.63566 ? 259 ALA A O   1 
ATOM   1973 C  CB  . ALA A 1 261 ? 0.27424   20.04709  0.04111   1.000 33.64735 ? 259 ALA A CB  1 
ATOM   1974 N  N   . TYR A 1 262 ? -1.06287  18.10586  2.17960   1.000 35.91361 ? 260 TYR A N   1 
ATOM   1975 C  CA  . TYR A 1 262 ? -2.11797  17.20288  2.61789   1.000 36.03254 ? 260 TYR A CA  1 
ATOM   1976 C  C   . TYR A 1 262 ? -2.88509  17.79017  3.79716   1.000 37.09403 ? 260 TYR A C   1 
ATOM   1977 O  O   . TYR A 1 262 ? -4.12346  17.72355  3.84504   1.000 32.22714 ? 260 TYR A O   1 
ATOM   1978 C  CB  . TYR A 1 262 ? -1.52076  15.85039  3.00060   1.000 37.43734 ? 260 TYR A CB  1 
ATOM   1979 C  CG  . TYR A 1 262 ? -2.47899  14.94554  3.74398   1.000 38.42331 ? 260 TYR A CG  1 
ATOM   1980 C  CD1 . TYR A 1 262 ? -3.38460  14.15252  3.05379   1.000 41.80725 ? 260 TYR A CD1 1 
ATOM   1981 C  CD2 . TYR A 1 262 ? -2.47440  14.87698  5.13916   1.000 43.57712 ? 260 TYR A CD2 1 
ATOM   1982 C  CE1 . TYR A 1 262 ? -4.25667  13.30644  3.72366   1.000 41.71985 ? 260 TYR A CE1 1 
ATOM   1983 C  CE2 . TYR A 1 262 ? -3.34667  14.03340  5.81980   1.000 48.54849 ? 260 TYR A CE2 1 
ATOM   1984 C  CZ  . TYR A 1 262 ? -4.22996  13.24828  5.10293   1.000 45.85093 ? 260 TYR A CZ  1 
ATOM   1985 O  OH  . TYR A 1 262 ? -5.09950  12.41336  5.75412   1.000 48.54166 ? 260 TYR A OH  1 
ATOM   1986 N  N   . TRP A 1 263 ? -2.16738  18.36663  4.75613   1.000 35.46813 ? 261 TRP A N   1 
ATOM   1987 C  CA  . TRP A 1 263 ? -2.84596  18.86469  5.95368   1.000 38.19827 ? 261 TRP A CA  1 
ATOM   1988 C  C   . TRP A 1 263 ? -3.64492  20.12245  5.65752   1.000 37.28752 ? 261 TRP A C   1 
ATOM   1989 O  O   . TRP A 1 263 ? -4.76539  20.26972  6.15099   1.000 35.33538 ? 261 TRP A O   1 
ATOM   1990 C  CB  . TRP A 1 263 ? -1.84436  19.10953  7.07649   1.000 40.01877 ? 261 TRP A CB  1 
ATOM   1991 C  CG  . TRP A 1 263 ? -1.39091  17.81251  7.67463   1.000 46.31527 ? 261 TRP A CG  1 
ATOM   1992 C  CD1 . TRP A 1 263 ? -0.15807  17.22962  7.54981   1.000 48.32221 ? 261 TRP A CD1 1 
ATOM   1993 C  CD2 . TRP A 1 263 ? -2.20228  16.87739  8.40307   1.000 46.12314 ? 261 TRP A CD2 1 
ATOM   1994 N  NE1 . TRP A 1 263 ? -0.13655  16.02322  8.20439   1.000 48.73832 ? 261 TRP A NE1 1 
ATOM   1995 C  CE2 . TRP A 1 263 ? -1.37848  15.77499  8.72826   1.000 49.20265 ? 261 TRP A CE2 1 
ATOM   1996 C  CE3 . TRP A 1 263 ? -3.53658  16.87598  8.83032   1.000 46.10094 ? 261 TRP A CE3 1 
ATOM   1997 C  CZ2 . TRP A 1 263 ? -1.84520  14.67842  9.46301   1.000 51.89906 ? 261 TRP A CZ2 1 
ATOM   1998 C  CZ3 . TRP A 1 263 ? -4.00299  15.78714  9.55642   1.000 49.68139 ? 261 TRP A CZ3 1 
ATOM   1999 C  CH2 . TRP A 1 263 ? -3.15670  14.70107  9.86274   1.000 55.48553 ? 261 TRP A CH2 1 
ATOM   2000 N  N   . LEU A 1 264 ? -3.11560  21.01580  4.80266   1.000 35.87458 ? 262 LEU A N   1 
ATOM   2001 C  CA  . LEU A 1 264 ? -3.83638  22.25323  4.50280   1.000 34.64900 ? 262 LEU A CA  1 
ATOM   2002 C  C   . LEU A 1 264 ? -5.00947  22.01446  3.57728   1.000 35.66762 ? 262 LEU A C   1 
ATOM   2003 O  O   . LEU A 1 264 ? -6.01872  22.72117  3.65918   1.000 37.24345 ? 262 LEU A O   1 
ATOM   2004 C  CB  . LEU A 1 264 ? -2.90638  23.28177  3.85951   1.000 32.19036 ? 262 LEU A CB  1 
ATOM   2005 C  CG  . LEU A 1 264 ? -1.75094  23.69144  4.74680   1.000 34.83022 ? 262 LEU A CG  1 
ATOM   2006 C  CD1 . LEU A 1 264 ? -0.85650  24.63774  3.96589   1.000 36.30522 ? 262 LEU A CD1 1 
ATOM   2007 C  CD2 . LEU A 1 264 ? -2.31085  24.36676  6.01531   1.000 35.65934 ? 262 LEU A CD2 1 
ATOM   2008 N  N   . LEU A 1 265 ? -4.88169  21.05998  2.66076   1.000 33.21966 ? 263 LEU A N   1 
ATOM   2009 C  CA  . LEU A 1 265 ? -5.85652  20.88567  1.59916   1.000 34.10351 ? 263 LEU A CA  1 
ATOM   2010 C  C   . LEU A 1 265 ? -6.73749  19.66520  1.77829   1.000 35.18927 ? 263 LEU A C   1 
ATOM   2011 O  O   . LEU A 1 265 ? -7.82221  19.61742  1.18787   1.000 35.57461 ? 263 LEU A O   1 
ATOM   2012 C  CB  . LEU A 1 265 ? -5.14661  20.77372  0.23973   1.000 32.59462 ? 263 LEU A CB  1 
ATOM   2013 C  CG  . LEU A 1 265 ? -4.41491  22.05462  -0.17835  1.000 37.14911 ? 263 LEU A CG  1 
ATOM   2014 C  CD1 . LEU A 1 265 ? -3.81915  21.89868  -1.56497  1.000 33.76588 ? 263 LEU A CD1 1 
ATOM   2015 C  CD2 . LEU A 1 265 ? -5.34957  23.25900  -0.11350  1.000 36.35828 ? 263 LEU A CD2 1 
ATOM   2016 N  N   . GLY A 1 266 ? -6.27792  18.66447  2.52089   1.000 35.03523 ? 264 GLY A N   1 
ATOM   2017 C  CA  . GLY A 1 266 ? -7.11923  17.53009  2.80749   1.000 36.67306 ? 264 GLY A CA  1 
ATOM   2018 C  C   . GLY A 1 266 ? -8.31909  17.94744  3.63257   1.000 41.72332 ? 264 GLY A C   1 
ATOM   2019 O  O   . GLY A 1 266 ? -8.17813  18.65854  4.63186   1.000 40.05507 ? 264 GLY A O   1 
ATOM   2020 N  N   . THR A 1 267 ? -9.50757  17.54294  3.21574   1.000 40.53918 ? 265 THR A N   1 
ATOM   2021 C  CA  . THR A 1 267 ? -10.68749 17.86677  3.99036   1.000 47.56637 ? 265 THR A CA  1 
ATOM   2022 C  C   . THR A 1 267 ? -10.87847 16.85587  5.09916   1.000 49.42687 ? 265 THR A C   1 
ATOM   2023 O  O   . THR A 1 267 ? -11.55891 15.86455  4.88963   1.000 55.91821 ? 265 THR A O   1 
ATOM   2024 C  CB  . THR A 1 267 ? -11.95665 17.90062  3.12934   1.000 49.74274 ? 265 THR A CB  1 
ATOM   2025 O  OG1 . THR A 1 267 ? -12.24885 16.58056  2.66542   1.000 51.90659 ? 265 THR A OG1 1 
ATOM   2026 C  CG2 . THR A 1 267 ? -11.80756 18.85229  1.96524   1.000 46.55360 ? 265 THR A CG2 1 
ATOM   2027 N  N   . LYS B 1 4   ? 41.21262  13.56591  -0.08495  1.000 61.18801 ? 2   LYS B N   1 
ATOM   2028 C  CA  . LYS B 1 4   ? 42.59999  14.00330  -0.22240  1.000 63.57865 ? 2   LYS B CA  1 
ATOM   2029 C  C   . LYS B 1 4   ? 42.80471  14.77632  -1.53067  1.000 64.10432 ? 2   LYS B C   1 
ATOM   2030 O  O   . LYS B 1 4   ? 43.74934  15.55883  -1.65489  1.000 68.24816 ? 2   LYS B O   1 
ATOM   2031 C  CB  . LYS B 1 4   ? 43.55399  12.79912  -0.15150  1.000 62.04752 ? 2   LYS B CB  1 
ATOM   2032 C  CG  . LYS B 1 4   ? 43.56369  12.08495  1.20541   1.000 63.77162 ? 2   LYS B CG  1 
ATOM   2033 C  CD  . LYS B 1 4   ? 44.97276  11.66017  1.64048   1.000 65.33611 ? 2   LYS B CD  1 
ATOM   2034 C  CE  . LYS B 1 4   ? 44.92266  10.49602  2.62889   1.000 66.23045 ? 2   LYS B CE  1 
ATOM   2035 N  NZ  . LYS B 1 4   ? 45.39595  9.21485   2.04188   1.000 62.62373 ? 2   LYS B NZ  1 
ATOM   2036 N  N   . ARG B 1 5   ? 41.91021  14.56449  -2.49609  1.000 58.89963 ? 3   ARG B N   1 
ATOM   2037 C  CA  . ARG B 1 5   ? 42.01441  15.18231  -3.81251  1.000 58.08493 ? 3   ARG B CA  1 
ATOM   2038 C  C   . ARG B 1 5   ? 40.62847  15.64365  -4.25376  1.000 56.76528 ? 3   ARG B C   1 
ATOM   2039 O  O   . ARG B 1 5   ? 39.60912  15.16900  -3.74738  1.000 57.40605 ? 3   ARG B O   1 
ATOM   2040 C  CB  . ARG B 1 5   ? 42.59724  14.20041  -4.83967  1.000 58.91760 ? 3   ARG B CB  1 
ATOM   2041 C  CG  . ARG B 1 5   ? 43.34502  14.84397  -5.99992  1.000 59.61808 ? 3   ARG B CG  1 
ATOM   2042 C  CD  . ARG B 1 5   ? 44.26397  13.83247  -6.70492  1.000 65.06153 ? 3   ARG B CD  1 
ATOM   2043 N  NE  . ARG B 1 5   ? 44.01413  13.81845  -8.14370  1.000 65.06527 ? 3   ARG B NE  1 
ATOM   2044 C  CZ  . ARG B 1 5   ? 44.15772  12.76421  -8.93701  1.000 65.93007 ? 3   ARG B CZ  1 
ATOM   2045 N  NH1 . ARG B 1 5   ? 44.57465  11.59560  -8.47289  1.000 66.32915 ? 3   ARG B NH1 1 
ATOM   2046 N  NH2 . ARG B 1 5   ? 43.86685  12.88336  -10.23093 1.000 66.86453 ? 3   ARG B NH2 1 
ATOM   2047 N  N   . SER B 1 6   ? 40.58934  16.56116  -5.22075  1.000 54.25410 ? 4   SER B N   1 
ATOM   2048 C  CA  . SER B 1 6   ? 39.31941  17.09815  -5.70348  1.000 56.09552 ? 4   SER B CA  1 
ATOM   2049 C  C   . SER B 1 6   ? 39.36476  17.30951  -7.21051  1.000 56.40707 ? 4   SER B C   1 
ATOM   2050 O  O   . SER B 1 6   ? 40.28992  17.94402  -7.72218  1.000 59.85749 ? 4   SER B O   1 
ATOM   2051 C  CB  . SER B 1 6   ? 38.97402  18.41885  -4.99685  1.000 56.66206 ? 4   SER B CB  1 
ATOM   2052 O  OG  . SER B 1 6   ? 38.27143  19.31748  -5.85266  1.000 57.10912 ? 4   SER B OG  1 
ATOM   2053 N  N   . LEU B 1 7   ? 38.35081  16.79528  -7.91597  1.000 55.61024 ? 5   LEU B N   1 
ATOM   2054 C  CA  . LEU B 1 7   ? 38.18887  17.00862  -9.35506  1.000 56.61680 ? 5   LEU B CA  1 
ATOM   2055 C  C   . LEU B 1 7   ? 37.92511  18.46040  -9.70679  1.000 58.39823 ? 5   LEU B C   1 
ATOM   2056 O  O   . LEU B 1 7   ? 37.81977  18.80794  -10.89196 1.000 55.96221 ? 5   LEU B O   1 
ATOM   2057 C  CB  . LEU B 1 7   ? 37.02940  16.15754  -9.88119  1.000 55.63942 ? 5   LEU B CB  1 
ATOM   2058 C  CG  . LEU B 1 7   ? 37.29183  14.70129  -10.23661 1.000 55.31424 ? 5   LEU B CG  1 
ATOM   2059 C  CD1 . LEU B 1 7   ? 36.03758  14.06001  -10.80412 1.000 51.87733 ? 5   LEU B CD1 1 
ATOM   2060 C  CD2 . LEU B 1 7   ? 38.43481  14.61958  -11.23553 1.000 56.53796 ? 5   LEU B CD2 1 
ATOM   2061 N  N   . ASN B 1 8   ? 37.84871  19.31040  -8.71579  1.000 58.17006 ? 6   ASN B N   1 
ATOM   2062 C  CA  . ASN B 1 8   ? 37.12146  20.54633  -8.87225  1.000 57.93134 ? 6   ASN B CA  1 
ATOM   2063 C  C   . ASN B 1 8   ? 37.84474  21.63551  -8.07871  1.000 58.83220 ? 6   ASN B C   1 
ATOM   2064 O  O   . ASN B 1 8   ? 37.22092  22.33448  -7.26913  1.000 57.38048 ? 6   ASN B O   1 
ATOM   2065 C  CB  . ASN B 1 8   ? 35.69244  20.26498  -8.38450  1.000 57.30026 ? 6   ASN B CB  1 
ATOM   2066 C  CG  . ASN B 1 8   ? 34.73715  21.34899  -8.72110  1.000 55.36696 ? 6   ASN B CG  1 
ATOM   2067 O  OD1 . ASN B 1 8   ? 33.84630  21.67212  -7.93783  1.000 53.27302 ? 6   ASN B OD1 1 
ATOM   2068 N  ND2 . ASN B 1 8   ? 34.90614  21.93014  -9.90776  1.000 57.80472 ? 6   ASN B ND2 1 
ATOM   2069 N  N   . PRO B 1 9   ? 39.16094  21.80503  -8.28332  1.000 61.11993 ? 7   PRO B N   1 
ATOM   2070 C  CA  . PRO B 1 9   ? 39.96070  22.55447  -7.29318  1.000 62.60506 ? 7   PRO B CA  1 
ATOM   2071 C  C   . PRO B 1 9   ? 39.62705  24.02836  -7.22681  1.000 60.62785 ? 7   PRO B C   1 
ATOM   2072 O  O   . PRO B 1 9   ? 39.62504  24.60152  -6.13183  1.000 67.18609 ? 7   PRO B O   1 
ATOM   2073 C  CB  . PRO B 1 9   ? 41.41083  22.35544  -7.75858  1.000 63.54751 ? 7   PRO B CB  1 
ATOM   2074 C  CG  . PRO B 1 9   ? 41.35336  21.77466  -9.10151  1.000 60.19198 ? 7   PRO B CG  1 
ATOM   2075 C  CD  . PRO B 1 9   ? 39.97693  21.28699  -9.39577  1.000 62.04665 ? 7   PRO B CD  1 
ATOM   2076 N  N   . ASP B 1 10  ? 39.36790  24.67134  -8.36262  1.000 60.83109 ? 8   ASP B N   1 
ATOM   2077 C  CA  . ASP B 1 10  ? 39.13621  26.11028  -8.35326  1.000 66.49527 ? 8   ASP B CA  1 
ATOM   2078 C  C   . ASP B 1 10  ? 37.74394  26.49334  -7.86844  1.000 66.03949 ? 8   ASP B C   1 
ATOM   2079 O  O   . ASP B 1 10  ? 37.45900  27.69007  -7.74944  1.000 65.44652 ? 8   ASP B O   1 
ATOM   2080 C  CB  . ASP B 1 10  ? 39.38106  26.70289  -9.74772  1.000 65.97836 ? 8   ASP B CB  1 
ATOM   2081 C  CG  . ASP B 1 10  ? 40.75516  26.35770  -10.29503 1.000 68.25367 ? 8   ASP B CG  1 
ATOM   2082 O  OD1 . ASP B 1 10  ? 41.72599  26.31552  -9.50279  1.000 69.80030 ? 8   ASP B OD1 1 
ATOM   2083 O  OD2 . ASP B 1 10  ? 40.86785  26.13507  -11.51927 1.000 70.72481 ? 8   ASP B OD2 1 
ATOM   2084 N  N   . GLU B 1 11  ? 36.87722  25.52860  -7.59308  1.000 63.94410 ? 9   GLU B N   1 
ATOM   2085 C  CA  . GLU B 1 11  ? 35.58082  25.85106  -7.02307  1.000 62.81668 ? 9   GLU B CA  1 
ATOM   2086 C  C   . GLU B 1 11  ? 35.78224  26.54096  -5.67797  1.000 65.80335 ? 9   GLU B C   1 
ATOM   2087 O  O   . GLU B 1 11  ? 36.32141  25.92181  -4.74708  1.000 63.37171 ? 9   GLU B O   1 
ATOM   2088 C  CB  . GLU B 1 11  ? 34.72630  24.59205  -6.87363  1.000 60.63413 ? 9   GLU B CB  1 
ATOM   2089 C  CG  . GLU B 1 11  ? 33.30548  24.81697  -6.33263  1.000 57.43537 ? 9   GLU B CG  1 
ATOM   2090 C  CD  . GLU B 1 11  ? 32.59878  26.03313  -6.92096  1.000 62.46431 ? 9   GLU B CD  1 
ATOM   2091 O  OE1 . GLU B 1 11  ? 32.38962  26.06875  -8.15565  1.000 61.16217 ? 9   GLU B OE1 1 
ATOM   2092 O  OE2 . GLU B 1 11  ? 32.24271  26.94947  -6.13699  1.000 62.96516 ? 9   GLU B OE2 1 
ATOM   2093 N  N   . PRO B 1 12  ? 35.40726  27.81857  -5.54301  1.000 67.13410 ? 10  PRO B N   1 
ATOM   2094 C  CA  . PRO B 1 12  ? 35.53691  28.47617  -4.22745  1.000 66.40672 ? 10  PRO B CA  1 
ATOM   2095 C  C   . PRO B 1 12  ? 34.67808  27.82749  -3.16029  1.000 63.74530 ? 10  PRO B C   1 
ATOM   2096 O  O   . PRO B 1 12  ? 35.17864  27.45734  -2.08841  1.000 64.59706 ? 10  PRO B O   1 
ATOM   2097 C  CB  . PRO B 1 12  ? 35.10247  29.92681  -4.50126  1.000 68.47286 ? 10  PRO B CB  1 
ATOM   2098 C  CG  . PRO B 1 12  ? 34.81736  30.03131  -5.96379  1.000 70.65599 ? 10  PRO B CG  1 
ATOM   2099 C  CD  . PRO B 1 12  ? 34.78019  28.67262  -6.56583  1.000 62.56090 ? 10  PRO B CD  1 
ATOM   2100 N  N   . ASN B 1 13  ? 33.38370  27.70110  -3.42176  1.000 64.46067 ? 11  ASN B N   1 
ATOM   2101 C  CA  . ASN B 1 13  ? 32.47938  27.03311  -2.49793  1.000 58.76821 ? 11  ASN B CA  1 
ATOM   2102 C  C   . ASN B 1 13  ? 32.92472  25.59545  -2.25526  1.000 59.78262 ? 11  ASN B C   1 
ATOM   2103 O  O   . ASN B 1 13  ? 32.94500  24.77663  -3.17919  1.000 58.87822 ? 11  ASN B O   1 
ATOM   2104 C  CB  . ASN B 1 13  ? 31.06448  27.09167  -3.06478  1.000 55.90095 ? 11  ASN B CB  1 
ATOM   2105 C  CG  . ASN B 1 13  ? 30.01747  26.82539  -2.02776  1.000 58.29646 ? 11  ASN B CG  1 
ATOM   2106 O  OD1 . ASN B 1 13  ? 30.28797  26.17974  -1.00864  1.000 58.78737 ? 11  ASN B OD1 1 
ATOM   2107 N  ND2 . ASN B 1 13  ? 28.80350  27.32152  -2.26910  1.000 60.98793 ? 11  ASN B ND2 1 
ATOM   2108 N  N   . ALA B 1 14  ? 33.29337  25.28884  -1.00882  1.000 56.66195 ? 12  ALA B N   1 
ATOM   2109 C  CA  . ALA B 1 14  ? 33.84298  23.97153  -0.70689  1.000 58.42712 ? 12  ALA B CA  1 
ATOM   2110 C  C   . ALA B 1 14  ? 32.77039  22.89400  -0.63228  1.000 54.97551 ? 12  ALA B C   1 
ATOM   2111 O  O   . ALA B 1 14  ? 33.08797  21.70751  -0.77613  1.000 55.55224 ? 12  ALA B O   1 
ATOM   2112 C  CB  . ALA B 1 14  ? 34.63177  24.01327  0.60178   1.000 56.69691 ? 12  ALA B CB  1 
ATOM   2113 N  N   . LEU B 1 15  ? 31.51056  23.27795  -0.41537  1.000 51.16455 ? 13  LEU B N   1 
ATOM   2114 C  CA  . LEU B 1 15  ? 30.42503  22.31150  -0.49075  1.000 52.96274 ? 13  LEU B CA  1 
ATOM   2115 C  C   . LEU B 1 15  ? 30.19385  21.81483  -1.91452  1.000 52.55358 ? 13  LEU B C   1 
ATOM   2116 O  O   . LEU B 1 15  ? 29.54296  20.77899  -2.09630  1.000 50.56492 ? 13  LEU B O   1 
ATOM   2117 C  CB  . LEU B 1 15  ? 29.13353  22.91539  0.05802   1.000 53.38637 ? 13  LEU B CB  1 
ATOM   2118 C  CG  . LEU B 1 15  ? 29.08795  23.25485  1.54881   1.000 53.41795 ? 13  LEU B CG  1 
ATOM   2119 C  CD1 . LEU B 1 15  ? 27.76331  23.93131  1.91218   1.000 51.36178 ? 13  LEU B CD1 1 
ATOM   2120 C  CD2 . LEU B 1 15  ? 29.32053  22.00548  2.37433   1.000 51.89711 ? 13  LEU B CD2 1 
ATOM   2121 N  N   . LEU B 1 16  ? 30.70350  22.52923  -2.92012  1.000 53.52359 ? 14  LEU B N   1 
ATOM   2122 C  CA  . LEU B 1 16  ? 30.55854  22.14728  -4.31821  1.000 51.52917 ? 14  LEU B CA  1 
ATOM   2123 C  C   . LEU B 1 16  ? 31.78590  21.42791  -4.86553  1.000 51.19851 ? 14  LEU B C   1 
ATOM   2124 O  O   . LEU B 1 16  ? 31.84333  21.15322  -6.06721  1.000 49.16904 ? 14  LEU B O   1 
ATOM   2125 C  CB  . LEU B 1 16  ? 30.25682  23.37637  -5.17602  1.000 52.34050 ? 14  LEU B CB  1 
ATOM   2126 C  CG  . LEU B 1 16  ? 28.98262  24.18226  -4.91795  1.000 50.85965 ? 14  LEU B CG  1 
ATOM   2127 C  CD1 . LEU B 1 16  ? 28.51998  24.85713  -6.20539  1.000 54.75020 ? 14  LEU B CD1 1 
ATOM   2128 C  CD2 . LEU B 1 16  ? 27.89539  23.32784  -4.37090  1.000 51.05375 ? 14  LEU B CD2 1 
ATOM   2129 N  N   . SER B 1 17  ? 32.76382  21.11173  -4.02197  1.000 51.60450 ? 15  SER B N   1 
ATOM   2130 C  CA  . SER B 1 17  ? 33.92875  20.36824  -4.48149  1.000 51.14402 ? 15  SER B CA  1 
ATOM   2131 C  C   . SER B 1 17  ? 33.60359  18.88605  -4.58645  1.000 51.24012 ? 15  SER B C   1 
ATOM   2132 O  O   . SER B 1 17  ? 32.96052  18.30956  -3.70116  1.000 47.53302 ? 15  SER B O   1 
ATOM   2133 C  CB  . SER B 1 17  ? 35.11247  20.55755  -3.53566  1.000 49.54020 ? 15  SER B CB  1 
ATOM   2134 O  OG  . SER B 1 17  ? 36.24384  19.84272  -4.00714  1.000 50.99163 ? 15  SER B OG  1 
ATOM   2135 N  N   . TYR B 1 18  ? 34.05042  18.27221  -5.68302  1.000 50.83013 ? 16  TYR B N   1 
ATOM   2136 C  CA  . TYR B 1 18  ? 33.96739  16.82310  -5.84522  1.000 46.76432 ? 16  TYR B CA  1 
ATOM   2137 C  C   . TYR B 1 18  ? 35.23517  16.21648  -5.26402  1.000 46.20292 ? 16  TYR B C   1 
ATOM   2138 O  O   . TYR B 1 18  ? 36.25181  16.07464  -5.94271  1.000 49.59619 ? 16  TYR B O   1 
ATOM   2139 C  CB  . TYR B 1 18  ? 33.78173  16.44191  -7.30606  1.000 47.27749 ? 16  TYR B CB  1 
ATOM   2140 C  CG  . TYR B 1 18  ? 33.36693  15.00283  -7.45067  1.000 44.87603 ? 16  TYR B CG  1 
ATOM   2141 C  CD1 . TYR B 1 18  ? 32.02970  14.64799  -7.39569  1.000 42.59692 ? 16  TYR B CD1 1 
ATOM   2142 C  CD2 . TYR B 1 18  ? 34.31541  13.99576  -7.62131  1.000 46.35758 ? 16  TYR B CD2 1 
ATOM   2143 C  CE1 . TYR B 1 18  ? 31.63475  13.33470  -7.52027  1.000 44.87578 ? 16  TYR B CE1 1 
ATOM   2144 C  CE2 . TYR B 1 18  ? 33.93025  12.67024  -7.74388  1.000 46.60287 ? 16  TYR B CE2 1 
ATOM   2145 C  CZ  . TYR B 1 18  ? 32.58169  12.35247  -7.68889  1.000 43.12475 ? 16  TYR B CZ  1 
ATOM   2146 O  OH  . TYR B 1 18  ? 32.17243  11.05705  -7.80505  1.000 48.96219 ? 16  TYR B OH  1 
ATOM   2147 N  N   . ASP B 1 19  ? 35.16421  15.85734  -3.98713  1.000 45.50933 ? 17  ASP B N   1 
ATOM   2148 C  CA  . ASP B 1 19  ? 36.29380  15.28862  -3.27123  1.000 48.54084 ? 17  ASP B CA  1 
ATOM   2149 C  C   . ASP B 1 19  ? 36.40541  13.79673  -3.55910  1.000 50.55862 ? 17  ASP B C   1 
ATOM   2150 O  O   . ASP B 1 19  ? 35.42023  13.05506  -3.45188  1.000 46.21641 ? 17  ASP B O   1 
ATOM   2151 C  CB  . ASP B 1 19  ? 36.12724  15.51788  -1.77092  1.000 50.48184 ? 17  ASP B CB  1 
ATOM   2152 C  CG  . ASP B 1 19  ? 36.21707  16.98342  -1.39626  1.000 53.10194 ? 17  ASP B CG  1 
ATOM   2153 O  OD1 . ASP B 1 19  ? 36.85100  17.75810  -2.15713  1.000 52.04582 ? 17  ASP B OD1 1 
ATOM   2154 O  OD2 . ASP B 1 19  ? 35.63831  17.35910  -0.35192  1.000 58.80282 ? 17  ASP B OD2 1 
ATOM   2155 N  N   . PHE B 1 20  ? 37.60878  13.35591  -3.91089  1.000 49.60356 ? 18  PHE B N   1 
ATOM   2156 C  CA  . PHE B 1 20  ? 37.83644  11.95393  -4.22118  1.000 48.77024 ? 18  PHE B CA  1 
ATOM   2157 C  C   . PHE B 1 20  ? 39.29503  11.61085  -3.95357  1.000 53.70817 ? 18  PHE B C   1 
ATOM   2158 O  O   . PHE B 1 20  ? 40.09472  12.46258  -3.54864  1.000 52.98384 ? 18  PHE B O   1 
ATOM   2159 C  CB  . PHE B 1 20  ? 37.43580  11.65053  -5.66197  1.000 48.53691 ? 18  PHE B CB  1 
ATOM   2160 C  CG  . PHE B 1 20  ? 38.46568  12.04444  -6.66990  1.000 50.92650 ? 18  PHE B CG  1 
ATOM   2161 C  CD1 . PHE B 1 20  ? 38.84088  13.36737  -6.80923  1.000 54.97802 ? 18  PHE B CD1 1 
ATOM   2162 C  CD2 . PHE B 1 20  ? 39.05958  11.09987  -7.48282  1.000 52.54929 ? 18  PHE B CD2 1 
ATOM   2163 C  CE1 . PHE B 1 20  ? 39.78523  13.74140  -7.74456  1.000 55.11699 ? 18  PHE B CE1 1 
ATOM   2164 C  CE2 . PHE B 1 20  ? 40.00624  11.46339  -8.41911  1.000 51.13637 ? 18  PHE B CE2 1 
ATOM   2165 C  CZ  . PHE B 1 20  ? 40.36808  12.79253  -8.54930  1.000 56.90385 ? 18  PHE B CZ  1 
ATOM   2166 N  N   . ASP B 1 21  ? 39.62831  10.33926  -4.18536  1.000 54.28854 ? 19  ASP B N   1 
ATOM   2167 C  CA  . ASP B 1 21  ? 40.97818  9.80772   -3.99064  1.000 55.69296 ? 19  ASP B CA  1 
ATOM   2168 C  C   . ASP B 1 21  ? 41.38415  9.88555   -2.51946  1.000 56.28685 ? 19  ASP B C   1 
ATOM   2169 O  O   . ASP B 1 21  ? 42.45722  10.38014  -2.16821  1.000 59.85351 ? 19  ASP B O   1 
ATOM   2170 C  CB  . ASP B 1 21  ? 41.99435  10.52816  -4.88019  1.000 53.94547 ? 19  ASP B CB  1 
ATOM   2171 C  CG  . ASP B 1 21  ? 43.30902  9.78967   -4.97120  1.000 59.06443 ? 19  ASP B CG  1 
ATOM   2172 O  OD1 . ASP B 1 21  ? 43.33921  8.60774   -4.57631  1.000 60.07893 ? 19  ASP B OD1 1 
ATOM   2173 O  OD2 . ASP B 1 21  ? 44.31269  10.38619  -5.42693  1.000 61.83630 ? 19  ASP B OD2 1 
ATOM   2174 N  N   . ARG B 1 22  ? 40.50218  9.40564   -1.65375  1.000 54.82317 ? 20  ARG B N   1 
ATOM   2175 C  CA  . ARG B 1 22  ? 40.77092  9.36881   -0.22699  1.000 56.43587 ? 20  ARG B CA  1 
ATOM   2176 C  C   . ARG B 1 22  ? 41.51014  8.10393   0.19191   1.000 57.48448 ? 20  ARG B C   1 
ATOM   2177 O  O   . ARG B 1 22  ? 41.74563  7.90523   1.38849   1.000 58.76749 ? 20  ARG B O   1 
ATOM   2178 C  CB  . ARG B 1 22  ? 39.45991  9.51349   0.55042   1.000 56.64872 ? 20  ARG B CB  1 
ATOM   2179 C  CG  . ARG B 1 22  ? 38.83448  10.90920  0.43258   1.000 57.83704 ? 20  ARG B CG  1 
ATOM   2180 C  CD  . ARG B 1 22  ? 37.40660  10.96139  0.98001   1.000 57.68175 ? 20  ARG B CD  1 
ATOM   2181 N  NE  . ARG B 1 22  ? 37.33914  10.70498  2.41551   1.000 63.59104 ? 20  ARG B NE  1 
ATOM   2182 C  CZ  . ARG B 1 22  ? 36.67233  9.69912   2.97434   1.000 64.19641 ? 20  ARG B CZ  1 
ATOM   2183 N  NH1 . ARG B 1 22  ? 36.02565  8.80162   2.24321   1.000 60.83444 ? 20  ARG B NH1 1 
ATOM   2184 N  NH2 . ARG B 1 22  ? 36.65642  9.58722   4.30097   1.000 62.40832 ? 20  ARG B NH2 1 
ATOM   2185 N  N   . GLY B 1 23  ? 41.89406  7.25741   -0.76423  1.000 54.89375 ? 21  GLY B N   1 
ATOM   2186 C  CA  . GLY B 1 23  ? 42.59553  6.03046   -0.44666  1.000 57.28811 ? 21  GLY B CA  1 
ATOM   2187 C  C   . GLY B 1 23  ? 41.79461  5.02433   0.34744   1.000 56.84965 ? 21  GLY B C   1 
ATOM   2188 O  O   . GLY B 1 23  ? 42.38089  4.17863   1.02847   1.000 58.27243 ? 21  GLY B O   1 
ATOM   2189 N  N   . SER B 1 24  ? 40.46887  5.08437   0.28778   1.000 53.84753 ? 22  SER B N   1 
ATOM   2190 C  CA  . SER B 1 24  ? 39.68066  4.12111   1.03730   1.000 53.20397 ? 22  SER B CA  1 
ATOM   2191 C  C   . SER B 1 24  ? 39.77609  2.74501   0.39100   1.000 56.22506 ? 22  SER B C   1 
ATOM   2192 O  O   . SER B 1 24  ? 40.12833  2.59820   -0.78256  1.000 57.14443 ? 22  SER B O   1 
ATOM   2193 C  CB  . SER B 1 24  ? 38.21826  4.54725   1.10567   1.000 55.20636 ? 22  SER B CB  1 
ATOM   2194 O  OG  . SER B 1 24  ? 37.51821  4.11912   -0.04910  1.000 53.67576 ? 22  SER B OG  1 
ATOM   2195 N  N   . ASN B 1 25  ? 39.44915  1.72263   1.17202   1.000 53.66253 ? 23  ASN B N   1 
ATOM   2196 C  CA  . ASN B 1 25  ? 39.50335  0.36541   0.63379   1.000 56.42299 ? 23  ASN B CA  1 
ATOM   2197 C  C   . ASN B 1 25  ? 38.44532  0.15179   -0.44300  1.000 53.02032 ? 23  ASN B C   1 
ATOM   2198 O  O   . ASN B 1 25  ? 38.67397  -0.58496  -1.40741  1.000 54.16101 ? 23  ASN B O   1 
ATOM   2199 C  CB  . ASN B 1 25  ? 39.33931  -0.64698  1.76090   1.000 53.76819 ? 23  ASN B CB  1 
ATOM   2200 C  CG  . ASN B 1 25  ? 40.67121  -1.07528  2.34803   1.000 58.50798 ? 23  ASN B CG  1 
ATOM   2201 O  OD1 . ASN B 1 25  ? 41.69110  -1.07054  1.65764   1.000 56.95404 ? 23  ASN B OD1 1 
ATOM   2202 N  ND2 . ASN B 1 25  ? 40.66769  -1.44754  3.62866   1.000 59.18774 ? 23  ASN B ND2 1 
ATOM   2203 N  N   . TYR B 1 26  ? 37.27198  0.76240   -0.28237  1.000 52.27019 ? 24  TYR B N   1 
ATOM   2204 C  CA  . TYR B 1 26  ? 36.29542  0.77272   -1.36161  1.000 49.91344 ? 24  TYR B CA  1 
ATOM   2205 C  C   . TYR B 1 26  ? 36.90044  1.36473   -2.62396  1.000 49.95228 ? 24  TYR B C   1 
ATOM   2206 O  O   . TYR B 1 26  ? 36.75819  0.80793   -3.71757  1.000 48.26212 ? 24  TYR B O   1 
ATOM   2207 C  CB  . TYR B 1 26  ? 35.06602  1.56543   -0.92913  1.000 50.70383 ? 24  TYR B CB  1 
ATOM   2208 C  CG  . TYR B 1 26  ? 34.05383  1.84583   -2.02020  1.000 47.75530 ? 24  TYR B CG  1 
ATOM   2209 C  CD1 . TYR B 1 26  ? 34.19041  2.94645   -2.87348  1.000 46.37929 ? 24  TYR B CD1 1 
ATOM   2210 C  CD2 . TYR B 1 26  ? 32.93342  1.02921   -2.16885  1.000 44.20320 ? 24  TYR B CD2 1 
ATOM   2211 C  CE1 . TYR B 1 26  ? 33.25119  3.21102   -3.86220  1.000 41.09249 ? 24  TYR B CE1 1 
ATOM   2212 C  CE2 . TYR B 1 26  ? 31.99465  1.28271   -3.14818  1.000 42.59817 ? 24  TYR B CE2 1 
ATOM   2213 C  CZ  . TYR B 1 26  ? 32.15779  2.37391   -3.99571  1.000 43.90299 ? 24  TYR B CZ  1 
ATOM   2214 O  OH  . TYR B 1 26  ? 31.22395  2.60869   -4.97005  1.000 36.63865 ? 24  TYR B OH  1 
ATOM   2215 N  N   . GLU B 1 27  ? 37.57650  2.50824   -2.49287  1.000 52.16118 ? 25  GLU B N   1 
ATOM   2216 C  CA  . GLU B 1 27  ? 38.22747  3.10597   -3.65179  1.000 51.86138 ? 25  GLU B CA  1 
ATOM   2217 C  C   . GLU B 1 27  ? 39.31137  2.18855   -4.20331  1.000 52.09902 ? 25  GLU B C   1 
ATOM   2218 O  O   . GLU B 1 27  ? 39.43822  2.02873   -5.42575  1.000 50.49215 ? 25  GLU B O   1 
ATOM   2219 C  CB  . GLU B 1 27  ? 38.81237  4.47173   -3.28730  1.000 55.14847 ? 25  GLU B CB  1 
ATOM   2220 C  CG  . GLU B 1 27  ? 37.83395  5.62870   -3.45235  1.000 52.94231 ? 25  GLU B CG  1 
ATOM   2221 C  CD  . GLU B 1 27  ? 38.17504  6.82157   -2.57608  1.000 53.09224 ? 25  GLU B CD  1 
ATOM   2222 O  OE1 . GLU B 1 27  ? 38.31336  6.65496   -1.34551  1.000 55.76775 ? 25  GLU B OE1 1 
ATOM   2223 O  OE2 . GLU B 1 27  ? 38.27382  7.93514   -3.11617  1.000 52.18075 ? 25  GLU B OE2 1 
ATOM   2224 N  N   . ASN B 1 28  ? 40.09716  1.56785   -3.31746  1.000 52.12320 ? 26  ASN B N   1 
ATOM   2225 C  CA  . ASN B 1 28  ? 41.21583  0.74332   -3.77407  1.000 53.96905 ? 26  ASN B CA  1 
ATOM   2226 C  C   . ASN B 1 28  ? 40.71622  -0.47225  -4.55054  1.000 53.11480 ? 26  ASN B C   1 
ATOM   2227 O  O   . ASN B 1 28  ? 41.24050  -0.79896  -5.62347  1.000 49.01821 ? 26  ASN B O   1 
ATOM   2228 C  CB  . ASN B 1 28  ? 42.07358  0.30319   -2.58079  1.000 53.89486 ? 26  ASN B CB  1 
ATOM   2229 C  CG  . ASN B 1 28  ? 42.73606  1.47299   -1.85800  1.000 54.94583 ? 26  ASN B CG  1 
ATOM   2230 O  OD1 . ASN B 1 28  ? 43.13257  2.46381   -2.47617  1.000 58.97814 ? 26  ASN B OD1 1 
ATOM   2231 N  ND2 . ASN B 1 28  ? 42.85077  1.36050   -0.53760  1.000 53.86744 ? 26  ASN B ND2 1 
ATOM   2232 N  N   . VAL B 1 29  ? 39.69052  -1.15035  -4.02215  1.000 50.53326 ? 27  VAL B N   1 
ATOM   2233 C  CA  . VAL B 1 29  ? 39.18610  -2.36573  -4.65802  1.000 49.87484 ? 27  VAL B CA  1 
ATOM   2234 C  C   . VAL B 1 29  ? 38.78221  -2.09270  -6.10071  1.000 49.74756 ? 27  VAL B C   1 
ATOM   2235 O  O   . VAL B 1 29  ? 39.05810  -2.89898  -6.99809  1.000 50.02567 ? 27  VAL B O   1 
ATOM   2236 C  CB  . VAL B 1 29  ? 38.01630  -2.95711  -3.84472  1.000 51.06123 ? 27  VAL B CB  1 
ATOM   2237 C  CG1 . VAL B 1 29  ? 37.35110  -4.09314  -4.61041  1.000 43.15813 ? 27  VAL B CG1 1 
ATOM   2238 C  CG2 . VAL B 1 29  ? 38.50151  -3.46687  -2.50249  1.000 52.71451 ? 27  VAL B CG2 1 
ATOM   2239 N  N   . LEU B 1 30  ? 38.15182  -0.94254  -6.35469  1.000 48.87008 ? 28  LEU B N   1 
ATOM   2240 C  CA  . LEU B 1 30  ? 37.54977  -0.65839  -7.65219  1.000 46.55771 ? 28  LEU B CA  1 
ATOM   2241 C  C   . LEU B 1 30  ? 38.48502  0.01164   -8.65344  1.000 46.34631 ? 28  LEU B C   1 
ATOM   2242 O  O   . LEU B 1 30  ? 38.06845  0.22971   -9.79678  1.000 47.77122 ? 28  LEU B O   1 
ATOM   2243 C  CB  . LEU B 1 30  ? 36.31138  0.21887   -7.46747  1.000 44.05303 ? 28  LEU B CB  1 
ATOM   2244 C  CG  . LEU B 1 30  ? 35.22473  -0.46056  -6.65175  1.000 42.65881 ? 28  LEU B CG  1 
ATOM   2245 C  CD1 . LEU B 1 30  ? 34.17125  0.56187   -6.22099  1.000 45.40916 ? 28  LEU B CD1 1 
ATOM   2246 C  CD2 . LEU B 1 30  ? 34.60162  -1.59818  -7.46199  1.000 41.65802 ? 28  LEU B CD2 1 
ATOM   2247 N  N   . HIS B 1 31  ? 39.72422  0.33907   -8.27320  1.000 47.15988 ? 29  HIS B N   1 
ATOM   2248 C  CA  . HIS B 1 31  ? 40.58241  1.19232   -9.09886  1.000 48.42999 ? 29  HIS B CA  1 
ATOM   2249 C  C   . HIS B 1 31  ? 39.81464  2.43770   -9.52865  1.000 43.83619 ? 29  HIS B C   1 
ATOM   2250 O  O   . HIS B 1 31  ? 39.85083  2.83964   -10.68951 1.000 42.42966 ? 29  HIS B O   1 
ATOM   2251 C  CB  . HIS B 1 31  ? 41.11693  0.46394   -10.33399 1.000 45.34007 ? 29  HIS B CB  1 
ATOM   2252 C  CG  . HIS B 1 31  ? 41.87289  -0.80149  -10.04552 1.000 48.99263 ? 29  HIS B CG  1 
ATOM   2253 N  ND1 . HIS B 1 31  ? 41.49542  -1.70458  -9.07197  1.000 47.15880 ? 29  HIS B ND1 1 
ATOM   2254 C  CD2 . HIS B 1 31  ? 42.97192  -1.32816  -10.63817 1.000 48.02668 ? 29  HIS B CD2 1 
ATOM   2255 C  CE1 . HIS B 1 31  ? 42.33961  -2.72035  -9.06747  1.000 49.21784 ? 29  HIS B CE1 1 
ATOM   2256 N  NE2 . HIS B 1 31  ? 43.24285  -2.51840  -10.00817 1.000 46.04716 ? 29  HIS B NE2 1 
ATOM   2257 N  N   . LEU B 1 32  ? 39.07442  3.02107   -8.58657  1.000 44.47163 ? 30  LEU B N   1 
ATOM   2258 C  CA  . LEU B 1 32  ? 38.13664  4.09383   -8.91398  1.000 45.40416 ? 30  LEU B CA  1 
ATOM   2259 C  C   . LEU B 1 32  ? 38.86489  5.38097   -9.27818  1.000 48.86743 ? 30  LEU B C   1 
ATOM   2260 O  O   . LEU B 1 32  ? 38.50278  6.05811   -10.24927 1.000 49.27234 ? 30  LEU B O   1 
ATOM   2261 C  CB  . LEU B 1 32  ? 37.18385  4.32512   -7.73822  1.000 45.22019 ? 30  LEU B CB  1 
ATOM   2262 C  CG  . LEU B 1 32  ? 36.17218  5.45767   -7.90292  1.000 47.53443 ? 30  LEU B CG  1 
ATOM   2263 C  CD1 . LEU B 1 32  ? 35.51994  5.44789   -9.27584  1.000 42.85175 ? 30  LEU B CD1 1 
ATOM   2264 C  CD2 . LEU B 1 32  ? 35.12404  5.34702   -6.81580  1.000 49.63217 ? 30  LEU B CD2 1 
ATOM   2265 N  N   . THR B 1 33  ? 39.88596  5.74446   -8.50212  1.000 46.50720 ? 31  THR B N   1 
ATOM   2266 C  CA  . THR B 1 33  ? 40.66150  6.93573   -8.82363  1.000 46.94314 ? 31  THR B CA  1 
ATOM   2267 C  C   . THR B 1 33  ? 41.20580  6.86390   -10.24901 1.000 48.52333 ? 31  THR B C   1 
ATOM   2268 O  O   . THR B 1 33  ? 41.18353  7.85870   -10.98620 1.000 42.71035 ? 31  THR B O   1 
ATOM   2269 C  CB  . THR B 1 33  ? 41.78189  7.10118   -7.79793  1.000 47.38020 ? 31  THR B CB  1 
ATOM   2270 O  OG1 . THR B 1 33  ? 41.19750  7.38677   -6.52176  1.000 52.53651 ? 31  THR B OG1 1 
ATOM   2271 C  CG2 . THR B 1 33  ? 42.71809  8.24009   -8.18636  1.000 49.85298 ? 31  THR B CG2 1 
ATOM   2272 N  N   . ASP B 1 34  ? 41.64174  5.67715   -10.67581 1.000 46.95706 ? 32  ASP B N   1 
ATOM   2273 C  CA  . ASP B 1 34  ? 42.10173  5.52246   -12.05309 1.000 47.52858 ? 32  ASP B CA  1 
ATOM   2274 C  C   . ASP B 1 34  ? 40.98133  5.82204   -13.04527 1.000 45.94440 ? 32  ASP B C   1 
ATOM   2275 O  O   . ASP B 1 34  ? 41.17994  6.55868   -14.01642 1.000 45.08327 ? 32  ASP B O   1 
ATOM   2276 C  CB  . ASP B 1 34  ? 42.64939  4.11517   -12.27429 1.000 45.89994 ? 32  ASP B CB  1 
ATOM   2277 C  CG  . ASP B 1 34  ? 44.10507  3.97834   -11.86442 1.000 54.18255 ? 32  ASP B CG  1 
ATOM   2278 O  OD1 . ASP B 1 34  ? 44.87464  4.95405   -12.03570 1.000 53.71337 ? 32  ASP B OD1 1 
ATOM   2279 O  OD2 . ASP B 1 34  ? 44.47803  2.88409   -11.37243 1.000 57.59687 ? 32  ASP B OD2 1 
ATOM   2280 N  N   . ALA B 1 35  ? 39.78829  5.27575   -12.80496 1.000 42.80862 ? 33  ALA B N   1 
ATOM   2281 C  CA  . ALA B 1 35  ? 38.68301  5.48287   -13.73655 1.000 43.25289 ? 33  ALA B CA  1 
ATOM   2282 C  C   . ALA B 1 35  ? 38.21321  6.93556   -13.74480 1.000 44.20338 ? 33  ALA B C   1 
ATOM   2283 O  O   . ALA B 1 35  ? 37.91729  7.49528   -14.81065 1.000 41.99464 ? 33  ALA B O   1 
ATOM   2284 C  CB  . ALA B 1 35  ? 37.53351  4.53659   -13.38618 1.000 43.97953 ? 33  ALA B CB  1 
ATOM   2285 N  N   . LEU B 1 36  ? 38.14433  7.57285   -12.56993 1.000 41.57657 ? 34  LEU B N   1 
ATOM   2286 C  CA  . LEU B 1 36  ? 37.77890  8.98542   -12.53052 1.000 43.97696 ? 34  LEU B CA  1 
ATOM   2287 C  C   . LEU B 1 36  ? 38.82888  9.86252   -13.20017 1.000 43.80009 ? 34  LEU B C   1 
ATOM   2288 O  O   . LEU B 1 36  ? 38.49178  10.94405  -13.70748 1.000 41.68626 ? 34  LEU B O   1 
ATOM   2289 C  CB  . LEU B 1 36  ? 37.54940  9.43814   -11.08531 1.000 42.83822 ? 34  LEU B CB  1 
ATOM   2290 C  CG  . LEU B 1 36  ? 36.24346  8.92606   -10.45799 1.000 42.35677 ? 34  LEU B CG  1 
ATOM   2291 C  CD1 . LEU B 1 36  ? 36.13213  9.27926   -8.96591  1.000 39.57618 ? 34  LEU B CD1 1 
ATOM   2292 C  CD2 . LEU B 1 36  ? 35.02865  9.41409   -11.22662 1.000 43.37351 ? 34  LEU B CD2 1 
ATOM   2293 N  N   . GLY B 1 37  ? 40.08362  9.40812   -13.24464 1.000 43.09808 ? 35  GLY B N   1 
ATOM   2294 C  CA  . GLY B 1 37  ? 41.13664  10.15599  -13.91234 1.000 43.74457 ? 35  GLY B CA  1 
ATOM   2295 C  C   . GLY B 1 37  ? 41.00167  10.22317  -15.41884 1.000 42.72428 ? 35  GLY B C   1 
ATOM   2296 O  O   . GLY B 1 37  ? 41.72896  10.98998  -16.05648 1.000 44.45595 ? 35  GLY B O   1 
ATOM   2297 N  N   . ALA B 1 38  ? 40.08897  9.45074   -16.00274 1.000 42.48805 ? 36  ALA B N   1 
ATOM   2298 C  CA  . ALA B 1 38  ? 39.89038  9.50325   -17.44258 1.000 42.71360 ? 36  ALA B CA  1 
ATOM   2299 C  C   . ALA B 1 38  ? 38.96594  10.63852  -17.86805 1.000 40.44122 ? 36  ALA B C   1 
ATOM   2300 O  O   . ALA B 1 38  ? 38.93956  10.98027  -19.05568 1.000 39.78078 ? 36  ALA B O   1 
ATOM   2301 C  CB  . ALA B 1 38  ? 39.33914  8.16316   -17.94357 1.000 39.05323 ? 36  ALA B CB  1 
ATOM   2302 N  N   . LEU B 1 39  ? 38.20841  11.22232  -16.94010 1.000 38.25091 ? 37  LEU B N   1 
ATOM   2303 C  CA  . LEU B 1 39  ? 37.34136  12.34932  -17.28477 1.000 40.81467 ? 37  LEU B CA  1 
ATOM   2304 C  C   . LEU B 1 39  ? 38.15427  13.53742  -17.79862 1.000 42.99683 ? 37  LEU B C   1 
ATOM   2305 O  O   . LEU B 1 39  ? 39.23817  13.83347  -17.28806 1.000 40.67423 ? 37  LEU B O   1 
ATOM   2306 C  CB  . LEU B 1 39  ? 36.52763  12.77873  -16.06689 1.000 39.50244 ? 37  LEU B CB  1 
ATOM   2307 C  CG  . LEU B 1 39  ? 35.57914  11.74544  -15.47531 1.000 42.18910 ? 37  LEU B CG  1 
ATOM   2308 C  CD1 . LEU B 1 39  ? 34.96609  12.30571  -14.24447 1.000 40.36839 ? 37  LEU B CD1 1 
ATOM   2309 C  CD2 . LEU B 1 39  ? 34.51876  11.35818  -16.48168 1.000 43.06574 ? 37  LEU B CD2 1 
ATOM   2310 N  N   . VAL B 1 40  ? 37.62867  14.21576  -18.81617 1.000 40.76042 ? 38  VAL B N   1 
ATOM   2311 C  CA  . VAL B 1 40  ? 38.32552  15.40949  -19.29931 1.000 43.64348 ? 38  VAL B CA  1 
ATOM   2312 C  C   . VAL B 1 40  ? 38.45847  16.39711  -18.14658 1.000 43.76984 ? 38  VAL B C   1 
ATOM   2313 O  O   . VAL B 1 40  ? 37.48567  16.62170  -17.40027 1.000 42.57856 ? 38  VAL B O   1 
ATOM   2314 C  CB  . VAL B 1 40  ? 37.58676  16.03229  -20.50209 1.000 46.00388 ? 38  VAL B CB  1 
ATOM   2315 C  CG1 . VAL B 1 40  ? 36.19265  16.47932  -20.10520 1.000 47.68206 ? 38  VAL B CG1 1 
ATOM   2316 C  CG2 . VAL B 1 40  ? 38.32768  17.25410  -21.01120 1.000 46.76214 ? 38  VAL B CG2 1 
ATOM   2317 N  N   . PRO B 1 41  ? 39.64151  16.94382  -17.89407 1.000 46.95956 ? 39  PRO B N   1 
ATOM   2318 C  CA  . PRO B 1 41  ? 39.78386  17.87725  -16.76979 1.000 47.40265 ? 39  PRO B CA  1 
ATOM   2319 C  C   . PRO B 1 41  ? 38.92262  19.11808  -16.97695 1.000 41.76544 ? 39  PRO B C   1 
ATOM   2320 O  O   . PRO B 1 41  ? 38.75072  19.59687  -18.09778 1.000 41.79174 ? 39  PRO B O   1 
ATOM   2321 C  CB  . PRO B 1 41  ? 41.28179  18.19960  -16.76365 1.000 48.66232 ? 39  PRO B CB  1 
ATOM   2322 C  CG  . PRO B 1 41  ? 41.92169  16.99599  -17.45291 1.000 48.41208 ? 39  PRO B CG  1 
ATOM   2323 C  CD  . PRO B 1 41  ? 40.93502  16.60005  -18.51495 1.000 46.75081 ? 39  PRO B CD  1 
ATOM   2324 N  N   . GLU B 1 42  ? 38.32749  19.59113  -15.88167 1.000 42.14921 ? 40  GLU B N   1 
ATOM   2325 C  CA  . GLU B 1 42  ? 37.44894  20.75612  -15.95657 1.000 48.78824 ? 40  GLU B CA  1 
ATOM   2326 C  C   . GLU B 1 42  ? 38.16210  21.94524  -16.58709 1.000 48.62167 ? 40  GLU B C   1 
ATOM   2327 O  O   . GLU B 1 42  ? 37.56226  22.71296  -17.35076 1.000 41.14397 ? 40  GLU B O   1 
ATOM   2328 C  CB  . GLU B 1 42  ? 36.94051  21.12408  -14.56476 1.000 49.70208 ? 40  GLU B CB  1 
ATOM   2329 C  CG  . GLU B 1 42  ? 35.75906  20.29322  -14.09159 1.000 49.94728 ? 40  GLU B CG  1 
ATOM   2330 C  CD  . GLU B 1 42  ? 34.94850  21.01757  -13.03282 1.000 50.67548 ? 40  GLU B CD  1 
ATOM   2331 O  OE1 . GLU B 1 42  ? 34.62784  22.21253  -13.23046 1.000 52.22047 ? 40  GLU B OE1 1 
ATOM   2332 O  OE2 . GLU B 1 42  ? 34.64084  20.39152  -11.99880 1.000 55.07748 ? 40  GLU B OE2 1 
ATOM   2333 N  N   . SER B 1 43  ? 39.45529  22.09070  -16.31003 1.000 47.79199 ? 41  SER B N   1 
ATOM   2334 C  CA  . SER B 1 43  ? 40.18887  23.19051  -16.89544 1.000 47.11422 ? 41  SER B CA  1 
ATOM   2335 C  C   . SER B 1 43  ? 40.38914  23.03336  -18.39573 1.000 52.56910 ? 41  SER B C   1 
ATOM   2336 O  O   . SER B 1 43  ? 40.89937  23.96527  -19.02278 1.000 51.39859 ? 41  SER B O   1 
ATOM   2337 C  CB  . SER B 1 43  ? 41.52773  23.35312  -16.18088 1.000 49.54036 ? 41  SER B CB  1 
ATOM   2338 O  OG  . SER B 1 43  ? 42.47251  22.41133  -16.63581 1.000 52.65962 ? 41  SER B OG  1 
ATOM   2339 N  N   . GLU B 1 44  ? 39.98791  21.90971  -19.00027 1.000 47.71321 ? 42  GLU B N   1 
ATOM   2340 C  CA  . GLU B 1 44  ? 40.14312  21.75885  -20.44468 1.000 51.29893 ? 42  GLU B CA  1 
ATOM   2341 C  C   . GLU B 1 44  ? 38.83289  21.65072  -21.21122 1.000 49.90842 ? 42  GLU B C   1 
ATOM   2342 O  O   . GLU B 1 44  ? 38.87807  21.58171  -22.44706 1.000 48.39964 ? 42  GLU B O   1 
ATOM   2343 C  CB  . GLU B 1 44  ? 41.00579  20.53242  -20.79636 1.000 54.38717 ? 42  GLU B CB  1 
ATOM   2344 C  CG  . GLU B 1 44  ? 42.27174  20.33643  -19.98115 1.000 52.48268 ? 42  GLU B CG  1 
ATOM   2345 C  CD  . GLU B 1 44  ? 43.09115  19.15261  -20.47777 1.000 59.57227 ? 42  GLU B CD  1 
ATOM   2346 O  OE1 . GLU B 1 44  ? 42.58239  18.38731  -21.33207 1.000 57.28431 ? 42  GLU B OE1 1 
ATOM   2347 O  OE2 . GLU B 1 44  ? 44.24454  18.99167  -20.02180 1.000 63.26761 ? 42  GLU B OE2 1 
ATOM   2348 N  N   . THR B 1 45  ? 37.67904  21.62130  -20.53701 1.000 47.60408 ? 43  THR B N   1 
ATOM   2349 C  CA  . THR B 1 45  ? 36.42571  21.43306  -21.26070 1.000 45.91823 ? 43  THR B CA  1 
ATOM   2350 C  C   . THR B 1 45  ? 36.14819  22.63752  -22.15476 1.000 47.56922 ? 43  THR B C   1 
ATOM   2351 O  O   . THR B 1 45  ? 36.39972  23.78445  -21.77944 1.000 45.41947 ? 43  THR B O   1 
ATOM   2352 C  CB  . THR B 1 45  ? 35.24933  21.18107  -20.29445 1.000 46.21441 ? 43  THR B CB  1 
ATOM   2353 O  OG1 . THR B 1 45  ? 35.21003  22.16440  -19.25253 1.000 43.07699 ? 43  THR B OG1 1 
ATOM   2354 C  CG2 . THR B 1 45  ? 35.36178  19.81415  -19.66393 1.000 44.13524 ? 43  THR B CG2 1 
ATOM   2355 N  N   . GLU B 1 46  ? 35.68107  22.36791  -23.37318 1.000 45.97352 ? 44  GLU B N   1 
ATOM   2356 C  CA  . GLU B 1 46  ? 35.37169  23.42647  -24.32090 1.000 45.79037 ? 44  GLU B CA  1 
ATOM   2357 C  C   . GLU B 1 46  ? 33.89215  23.77829  -24.36863 1.000 48.38465 ? 44  GLU B C   1 
ATOM   2358 O  O   . GLU B 1 46  ? 33.53303  24.78455  -24.99518 1.000 46.35760 ? 44  GLU B O   1 
ATOM   2359 C  CB  . GLU B 1 46  ? 35.83493  23.04031  -25.73107 1.000 50.61893 ? 44  GLU B CB  1 
ATOM   2360 C  CG  . GLU B 1 46  ? 37.34449  22.88849  -25.89783 1.000 58.27021 ? 44  GLU B CG  1 
ATOM   2361 C  CD  . GLU B 1 46  ? 37.75925  22.75970  -27.36808 1.000 59.23243 ? 44  GLU B CD  1 
ATOM   2362 O  OE1 . GLU B 1 46  ? 37.89915  21.61746  -27.85947 1.000 62.32623 ? 44  GLU B OE1 1 
ATOM   2363 O  OE2 . GLU B 1 46  ? 37.94065  23.79779  -28.03200 1.000 61.22607 ? 44  GLU B OE2 1 
ATOM   2364 N  N   . HIS B 1 47  ? 33.03112  22.97774  -23.73401 1.000 45.07381 ? 45  HIS B N   1 
ATOM   2365 C  CA  . HIS B 1 47  ? 31.59428  23.18707  -23.70788 1.000 41.68272 ? 45  HIS B CA  1 
ATOM   2366 C  C   . HIS B 1 47  ? 31.05209  22.58148  -22.41114 1.000 37.99179 ? 45  HIS B C   1 
ATOM   2367 O  O   . HIS B 1 47  ? 31.54188  21.52456  -21.98265 1.000 37.58399 ? 45  HIS B O   1 
ATOM   2368 C  CB  . HIS B 1 47  ? 30.91133  22.55742  -24.94027 1.000 35.83800 ? 45  HIS B CB  1 
ATOM   2369 C  CG  . HIS B 1 47  ? 29.50460  23.04022  -25.15634 1.000 39.56748 ? 45  HIS B CG  1 
ATOM   2370 N  ND1 . HIS B 1 47  ? 28.43559  22.56243  -24.42120 1.000 35.04128 ? 45  HIS B ND1 1 
ATOM   2371 C  CD2 . HIS B 1 47  ? 28.99281  23.96942  -26.00342 1.000 34.44959 ? 45  HIS B CD2 1 
ATOM   2372 C  CE1 . HIS B 1 47  ? 27.33175  23.19325  -24.79066 1.000 35.99354 ? 45  HIS B CE1 1 
ATOM   2373 N  NE2 . HIS B 1 47  ? 27.63903  24.04867  -25.75240 1.000 34.00595 ? 45  HIS B NE2 1 
ATOM   2374 N  N   . PRO B 1 48  ? 30.07807  23.21799  -21.74785 1.000 38.57837 ? 46  PRO B N   1 
ATOM   2375 C  CA  . PRO B 1 48  ? 29.55901  22.63260  -20.49041 1.000 34.62494 ? 46  PRO B CA  1 
ATOM   2376 C  C   . PRO B 1 48  ? 28.86312  21.29480  -20.69994 1.000 35.34474 ? 46  PRO B C   1 
ATOM   2377 O  O   . PRO B 1 48  ? 28.68592  20.53889  -19.73280 1.000 36.61217 ? 46  PRO B O   1 
ATOM   2378 C  CB  . PRO B 1 48  ? 28.58002  23.69113  -19.95861 1.000 38.58194 ? 46  PRO B CB  1 
ATOM   2379 C  CG  . PRO B 1 48  ? 28.44226  24.72664  -21.02508 1.000 39.52425 ? 46  PRO B CG  1 
ATOM   2380 C  CD  . PRO B 1 48  ? 29.31472  24.39516  -22.19875 1.000 36.73053 ? 46  PRO B CD  1 
ATOM   2381 N  N   . ASP B 1 49  ? 28.49281  20.95684  -21.93383 1.000 34.25191 ? 47  ASP B N   1 
ATOM   2382 C  CA  . ASP B 1 49  ? 27.86979  19.66868  -22.21973 1.000 34.08272 ? 47  ASP B CA  1 
ATOM   2383 C  C   . ASP B 1 49  ? 28.88483  18.60244  -22.59957 1.000 36.33355 ? 47  ASP B C   1 
ATOM   2384 O  O   . ASP B 1 49  ? 28.49235  17.46565  -22.87934 1.000 33.45254 ? 47  ASP B O   1 
ATOM   2385 C  CB  . ASP B 1 49  ? 26.83828  19.83445  -23.33462 1.000 31.58782 ? 47  ASP B CB  1 
ATOM   2386 C  CG  . ASP B 1 49  ? 25.57694  20.48719  -22.85440 1.000 31.86059 ? 47  ASP B CG  1 
ATOM   2387 O  OD1 . ASP B 1 49  ? 25.19522  20.23595  -21.67851 1.000 31.32513 ? 47  ASP B OD1 1 
ATOM   2388 O  OD2 . ASP B 1 49  ? 24.96685  21.25043  -23.63819 1.000 32.48839 ? 47  ASP B OD2 1 
ATOM   2389 N  N   . GLN B 1 50  ? 30.17558  18.95260  -22.60986 1.000 35.78723 ? 48  GLN B N   1 
ATOM   2390 C  CA  . GLN B 1 50  ? 31.21304  18.01190  -22.99713 1.000 34.76102 ? 48  GLN B CA  1 
ATOM   2391 C  C   . GLN B 1 50  ? 31.28903  16.82552  -22.04094 1.000 36.35525 ? 48  GLN B C   1 
ATOM   2392 O  O   . GLN B 1 50  ? 31.41489  15.67928  -22.48342 1.000 32.33015 ? 48  GLN B O   1 
ATOM   2393 C  CB  . GLN B 1 50  ? 32.56831  18.71695  -23.05744 1.000 36.12547 ? 48  GLN B CB  1 
ATOM   2394 C  CG  . GLN B 1 50  ? 33.69450  17.80664  -23.55018 1.000 40.54184 ? 48  GLN B CG  1 
ATOM   2395 C  CD  . GLN B 1 50  ? 34.99845  18.56618  -23.80340 1.000 45.98576 ? 48  GLN B CD  1 
ATOM   2396 O  OE1 . GLN B 1 50  ? 35.01480  19.80287  -23.85167 1.000 43.07123 ? 48  GLN B OE1 1 
ATOM   2397 N  NE2 . GLN B 1 50  ? 36.09181  17.82805  -23.95572 1.000 41.38409 ? 48  GLN B NE2 1 
ATOM   2398 N  N   . ARG B 1 51  ? 31.22304  17.07982  -20.72844 1.000 33.79404 ? 49  ARG B N   1 
ATOM   2399 C  CA  . ARG B 1 51  ? 31.31790  15.98890  -19.75929 1.000 31.69370 ? 49  ARG B CA  1 
ATOM   2400 C  C   . ARG B 1 51  ? 30.18340  14.97858  -19.92352 1.000 32.95399 ? 49  ARG B C   1 
ATOM   2401 O  O   . ARG B 1 51  ? 30.40115  13.75900  -19.85010 1.000 33.91447 ? 49  ARG B O   1 
ATOM   2402 C  CB  . ARG B 1 51  ? 31.31940  16.57403  -18.34781 1.000 35.60411 ? 49  ARG B CB  1 
ATOM   2403 C  CG  . ARG B 1 51  ? 32.71508  16.90092  -17.85080 1.000 39.23121 ? 49  ARG B CG  1 
ATOM   2404 C  CD  . ARG B 1 51  ? 33.49128  15.63889  -17.46215 1.000 42.15583 ? 49  ARG B CD  1 
ATOM   2405 N  NE  . ARG B 1 51  ? 34.77010  15.98729  -16.85198 1.000 44.46428 ? 49  ARG B NE  1 
ATOM   2406 C  CZ  . ARG B 1 51  ? 34.92535  16.32945  -15.57767 1.000 45.87577 ? 49  ARG B CZ  1 
ATOM   2407 N  NH1 . ARG B 1 51  ? 33.91609  16.29225  -14.72188 1.000 40.89581 ? 49  ARG B NH1 1 
ATOM   2408 N  NH2 . ARG B 1 51  ? 36.12146  16.73457  -15.15648 1.000 46.73762 ? 49  ARG B NH2 1 
ATOM   2409 N  N   . PHE B 1 52  ? 28.96219  15.45722  -20.13779 1.000 29.97950 ? 50  PHE B N   1 
ATOM   2410 C  CA  . PHE B 1 52  ? 27.83660  14.54826  -20.33323 1.000 29.39685 ? 50  PHE B CA  1 
ATOM   2411 C  C   . PHE B 1 52  ? 28.08144  13.66538  -21.54768 1.000 33.05225 ? 50  PHE B C   1 
ATOM   2412 O  O   . PHE B 1 52  ? 27.92129  12.44531  -21.49253 1.000 31.07469 ? 50  PHE B O   1 
ATOM   2413 C  CB  . PHE B 1 52  ? 26.55689  15.37278  -20.50252 1.000 33.40974 ? 50  PHE B CB  1 
ATOM   2414 C  CG  . PHE B 1 52  ? 25.29574  14.55769  -20.66997 1.000 29.88580 ? 50  PHE B CG  1 
ATOM   2415 C  CD1 . PHE B 1 52  ? 24.91604  13.62825  -19.72629 1.000 33.96892 ? 50  PHE B CD1 1 
ATOM   2416 C  CD2 . PHE B 1 52  ? 24.46132  14.77522  -21.74970 1.000 32.27124 ? 50  PHE B CD2 1 
ATOM   2417 C  CE1 . PHE B 1 52  ? 23.73956  12.91280  -19.88259 1.000 31.99931 ? 50  PHE B CE1 1 
ATOM   2418 C  CE2 . PHE B 1 52  ? 23.28852  14.05273  -21.91465 1.000 29.81937 ? 50  PHE B CE2 1 
ATOM   2419 C  CZ  . PHE B 1 52  ? 22.92967  13.14604  -20.97767 1.000 31.33436 ? 50  PHE B CZ  1 
ATOM   2420 N  N   . PHE B 1 53  ? 28.50661  14.28446  -22.64994 1.000 32.92649 ? 51  PHE B N   1 
ATOM   2421 C  CA  . PHE B 1 53  ? 28.90631  13.55228  -23.84421 1.000 33.31836 ? 51  PHE B CA  1 
ATOM   2422 C  C   . PHE B 1 53  ? 29.88905  12.42536  -23.50442 1.000 32.75897 ? 51  PHE B C   1 
ATOM   2423 O  O   . PHE B 1 53  ? 29.63319  11.24939  -23.79137 1.000 33.55252 ? 51  PHE B O   1 
ATOM   2424 C  CB  . PHE B 1 53  ? 29.50191  14.56651  -24.81376 1.000 31.79421 ? 51  PHE B CB  1 
ATOM   2425 C  CG  . PHE B 1 53  ? 29.87922  14.02357  -26.15180 1.000 32.73756 ? 51  PHE B CG  1 
ATOM   2426 C  CD1 . PHE B 1 53  ? 31.13302  13.48230  -26.36087 1.000 32.02051 ? 51  PHE B CD1 1 
ATOM   2427 C  CD2 . PHE B 1 53  ? 29.00313  14.13212  -27.22155 1.000 33.47660 ? 51  PHE B CD2 1 
ATOM   2428 C  CE1 . PHE B 1 53  ? 31.49573  13.00118  -27.63634 1.000 36.69580 ? 51  PHE B CE1 1 
ATOM   2429 C  CE2 . PHE B 1 53  ? 29.35362  13.66659  -28.48970 1.000 34.87836 ? 51  PHE B CE2 1 
ATOM   2430 C  CZ  . PHE B 1 53  ? 30.59931  13.09423  -28.69361 1.000 33.76352 ? 51  PHE B CZ  1 
ATOM   2431 N  N   . GLN B 1 54  ? 30.99513  12.75965  -22.83701 1.000 31.86037 ? 52  GLN B N   1 
ATOM   2432 C  CA  . GLN B 1 54  ? 32.01593  11.74935  -22.57568 1.000 32.49011 ? 52  GLN B CA  1 
ATOM   2433 C  C   . GLN B 1 54  ? 31.50245  10.65296  -21.64430 1.000 34.17830 ? 52  GLN B C   1 
ATOM   2434 O  O   . GLN B 1 54  ? 31.78147  9.47665   -21.86784 1.000 31.04637 ? 52  GLN B O   1 
ATOM   2435 C  CB  . GLN B 1 54  ? 33.27179  12.39283  -21.98777 1.000 35.17950 ? 52  GLN B CB  1 
ATOM   2436 C  CG  . GLN B 1 54  ? 34.39087  11.39480  -21.70336 1.000 35.04204 ? 52  GLN B CG  1 
ATOM   2437 C  CD  . GLN B 1 54  ? 35.52417  11.98567  -20.86337 1.000 40.86076 ? 52  GLN B CD  1 
ATOM   2438 O  OE1 . GLN B 1 54  ? 35.32513  12.93823  -20.08836 1.000 39.07413 ? 52  GLN B OE1 1 
ATOM   2439 N  NE2 . GLN B 1 54  ? 36.70804  11.38555  -20.97086 1.000 38.38922 ? 52  GLN B NE2 1 
ATOM   2440 N  N   . VAL B 1 55  ? 30.76476  11.01224  -20.59061 1.000 33.61478 ? 53  VAL B N   1 
ATOM   2441 C  CA  . VAL B 1 55  ? 30.39244  10.01901  -19.59294 1.000 31.73664 ? 53  VAL B CA  1 
ATOM   2442 C  C   . VAL B 1 55  ? 29.45664  8.96744   -20.18975 1.000 33.38030 ? 53  VAL B C   1 
ATOM   2443 O  O   . VAL B 1 55  ? 29.61919  7.76909   -19.93495 1.000 32.42623 ? 53  VAL B O   1 
ATOM   2444 C  CB  . VAL B 1 55  ? 29.78245  10.68617  -18.34080 1.000 34.66061 ? 53  VAL B CB  1 
ATOM   2445 C  CG1 . VAL B 1 55  ? 29.01965  9.64852   -17.48810 1.000 34.02344 ? 53  VAL B CG1 1 
ATOM   2446 C  CG2 . VAL B 1 55  ? 30.86535  11.28736  -17.49909 1.000 33.21601 ? 53  VAL B CG2 1 
ATOM   2447 N  N   . THR B 1 56  ? 28.48967  9.37649   -21.01571 1.000 31.93513 ? 54  THR B N   1 
ATOM   2448 C  CA  . THR B 1 56  ? 27.60313  8.38098   -21.62032 1.000 31.76186 ? 54  THR B CA  1 
ATOM   2449 C  C   . THR B 1 56  ? 28.36764  7.36332   -22.47589 1.000 31.93201 ? 54  THR B C   1 
ATOM   2450 O  O   . THR B 1 56  ? 27.97132  6.19990   -22.53320 1.000 30.26428 ? 54  THR B O   1 
ATOM   2451 C  CB  . THR B 1 56  ? 26.51266  9.04925   -22.44987 1.000 31.92611 ? 54  THR B CB  1 
ATOM   2452 O  OG1 . THR B 1 56  ? 27.10681  9.70476   -23.57889 1.000 33.27022 ? 54  THR B OG1 1 
ATOM   2453 C  CG2 . THR B 1 56  ? 25.77928  10.09726  -21.59270 1.000 28.61060 ? 54  THR B CG2 1 
ATOM   2454 N  N   . HIS B 1 57  ? 29.44716  7.77852   -23.16714 1.000 31.37115 ? 55  HIS B N   1 
ATOM   2455 C  CA  . HIS B 1 57  ? 30.23845  6.81356   -23.94503 1.000 34.17040 ? 55  HIS B CA  1 
ATOM   2456 C  C   . HIS B 1 57  ? 31.03103  5.88355   -23.02634 1.000 33.98420 ? 55  HIS B C   1 
ATOM   2457 O  O   . HIS B 1 57  ? 31.14688  4.67063   -23.29073 1.000 32.22595 ? 55  HIS B O   1 
ATOM   2458 C  CB  . HIS B 1 57  ? 31.23426  7.51189   -24.88582 1.000 31.18451 ? 55  HIS B CB  1 
ATOM   2459 C  CG  . HIS B 1 57  ? 30.62957  8.25995   -26.04112 1.000 31.79463 ? 55  HIS B CG  1 
ATOM   2460 N  ND1 . HIS B 1 57  ? 30.10479  9.53207   -25.91351 1.000 34.00109 ? 55  HIS B ND1 1 
ATOM   2461 C  CD2 . HIS B 1 57  ? 30.57114  7.96398   -27.36556 1.000 31.97314 ? 55  HIS B CD2 1 
ATOM   2462 C  CE1 . HIS B 1 57  ? 29.70690  9.96510   -27.09793 1.000 32.11217 ? 55  HIS B CE1 1 
ATOM   2463 N  NE2 . HIS B 1 57  ? 29.97005  9.03165   -27.99394 1.000 30.02180 ? 55  HIS B NE2 1 
ATOM   2464 N  N   . LEU B 1 58  ? 31.63967  6.44394   -21.97508 1.000 33.93397 ? 56  LEU B N   1 
ATOM   2465 C  CA  . LEU B 1 58  ? 32.44343  5.61710   -21.08117 1.000 34.21933 ? 56  LEU B CA  1 
ATOM   2466 C  C   . LEU B 1 58  ? 31.57767  4.58451   -20.37853 1.000 34.15931 ? 56  LEU B C   1 
ATOM   2467 O  O   . LEU B 1 58  ? 31.99096  3.43344   -20.19606 1.000 34.22825 ? 56  LEU B O   1 
ATOM   2468 C  CB  . LEU B 1 58  ? 33.17394  6.49164   -20.06475 1.000 34.27671 ? 56  LEU B CB  1 
ATOM   2469 C  CG  . LEU B 1 58  ? 34.16631  7.48692   -20.64589 1.000 37.05653 ? 56  LEU B CG  1 
ATOM   2470 C  CD1 . LEU B 1 58  ? 35.00880  8.13187   -19.55411 1.000 39.35756 ? 56  LEU B CD1 1 
ATOM   2471 C  CD2 . LEU B 1 58  ? 35.05266  6.81271   -21.68247 1.000 39.69218 ? 56  LEU B CD2 1 
ATOM   2472 N  N   . ILE B 1 59  ? 30.36538  4.97873   -19.98002 1.000 31.92174 ? 57  ILE B N   1 
ATOM   2473 C  CA  . ILE B 1 59  ? 29.40157  4.01945   -19.44275 1.000 30.53098 ? 57  ILE B CA  1 
ATOM   2474 C  C   . ILE B 1 59  ? 29.09600  2.94415   -20.47441 1.000 28.53630 ? 57  ILE B C   1 
ATOM   2475 O  O   . ILE B 1 59  ? 29.05075  1.75795   -20.14849 1.000 30.55169 ? 57  ILE B O   1 
ATOM   2476 C  CB  . ILE B 1 59  ? 28.12555  4.75323   -18.97469 1.000 29.98945 ? 57  ILE B CB  1 
ATOM   2477 C  CG1 . ILE B 1 59  ? 28.42825  5.55841   -17.70780 1.000 30.38554 ? 57  ILE B CG1 1 
ATOM   2478 C  CG2 . ILE B 1 59  ? 26.96038  3.74544   -18.72103 1.000 28.47554 ? 57  ILE B CG2 1 
ATOM   2479 C  CD1 . ILE B 1 59  ? 27.21143  6.27552   -17.10401 1.000 29.33379 ? 57  ILE B CD1 1 
ATOM   2480 N  N   . THR B 1 60  ? 28.94397  3.32901   -21.74671 1.000 30.01028 ? 58  THR B N   1 
ATOM   2481 C  CA  . THR B 1 60  ? 28.63077  2.33357   -22.77486 1.000 29.34360 ? 58  THR B CA  1 
ATOM   2482 C  C   . THR B 1 60  ? 29.79027  1.35370   -22.97276 1.000 32.96600 ? 58  THR B C   1 
ATOM   2483 O  O   . THR B 1 60  ? 29.58379  0.13033   -23.05312 1.000 32.27968 ? 58  THR B O   1 
ATOM   2484 C  CB  . THR B 1 60  ? 28.28025  3.04113   -24.08603 1.000 30.04737 ? 58  THR B CB  1 
ATOM   2485 O  OG1 . THR B 1 60  ? 27.12423  3.88184   -23.88581 1.000 28.40490 ? 58  THR B OG1 1 
ATOM   2486 C  CG2 . THR B 1 60  ? 27.99950  2.02271   -25.21198 1.000 27.94952 ? 58  THR B CG2 1 
ATOM   2487 N  N   . GLU B 1 61  ? 31.01711  1.87524   -23.04705 1.000 31.86444 ? 59  GLU B N   1 
ATOM   2488 C  CA  . GLU B 1 61  ? 32.18781  1.03799   -23.27713 1.000 31.58897 ? 59  GLU B CA  1 
ATOM   2489 C  C   . GLU B 1 61  ? 32.46692  0.10807   -22.10264 1.000 30.63739 ? 59  GLU B C   1 
ATOM   2490 O  O   . GLU B 1 61  ? 32.93441  -1.02244  -22.30529 1.000 34.45055 ? 59  GLU B O   1 
ATOM   2491 C  CB  . GLU B 1 61  ? 33.40701  1.92193   -23.56930 1.000 31.04045 ? 59  GLU B CB  1 
ATOM   2492 C  CG  . GLU B 1 61  ? 33.28805  2.74734   -24.84610 1.000 32.52745 ? 59  GLU B CG  1 
ATOM   2493 C  CD  . GLU B 1 61  ? 33.41013  1.91997   -26.12724 1.000 34.78592 ? 59  GLU B CD  1 
ATOM   2494 O  OE1 . GLU B 1 61  ? 33.80938  0.74056   -26.03509 1.000 34.90864 ? 59  GLU B OE1 1 
ATOM   2495 O  OE2 . GLU B 1 61  ? 33.10166  2.45085   -27.21937 1.000 32.35079 ? 59  GLU B OE2 1 
ATOM   2496 N  N   . TYR B 1 62  ? 32.20216  0.55280   -20.87258 1.000 32.40079 ? 60  TYR B N   1 
ATOM   2497 C  CA  . TYR B 1 62  ? 32.28285  -0.36324  -19.73706 1.000 32.74725 ? 60  TYR B CA  1 
ATOM   2498 C  C   . TYR B 1 62  ? 31.23999  -1.45827  -19.85315 1.000 34.03701 ? 60  TYR B C   1 
ATOM   2499 O  O   . TYR B 1 62  ? 31.52173  -2.63189  -19.57703 1.000 34.45114 ? 60  TYR B O   1 
ATOM   2500 C  CB  . TYR B 1 62  ? 32.08628  0.39490   -18.42031 1.000 34.04725 ? 60  TYR B CB  1 
ATOM   2501 C  CG  . TYR B 1 62  ? 33.34238  0.98720   -17.83818 1.000 36.27463 ? 60  TYR B CG  1 
ATOM   2502 C  CD1 . TYR B 1 62  ? 34.59895  0.44400   -18.10194 1.000 42.34269 ? 60  TYR B CD1 1 
ATOM   2503 C  CD2 . TYR B 1 62  ? 33.28011  2.09839   -17.02465 1.000 40.42061 ? 60  TYR B CD2 1 
ATOM   2504 C  CE1 . TYR B 1 62  ? 35.76441  1.01926   -17.56580 1.000 41.48143 ? 60  TYR B CE1 1 
ATOM   2505 C  CE2 . TYR B 1 62  ? 34.41400  2.65509   -16.48850 1.000 39.29960 ? 60  TYR B CE2 1 
ATOM   2506 C  CZ  . TYR B 1 62  ? 35.65000  2.12213   -16.75206 1.000 43.36467 ? 60  TYR B CZ  1 
ATOM   2507 O  OH  . TYR B 1 62  ? 36.75260  2.73475   -16.18717 1.000 43.88196 ? 60  TYR B OH  1 
ATOM   2508 N  N   . ALA B 1 63  ? 30.01474  -1.10166  -20.23382 1.000 29.25804 ? 61  ALA B N   1 
ATOM   2509 C  CA  . ALA B 1 63  ? 29.02133  -2.15015  -20.39171 1.000 32.67883 ? 61  ALA B CA  1 
ATOM   2510 C  C   . ALA B 1 63  ? 29.45001  -3.14788  -21.46553 1.000 33.06495 ? 61  ALA B C   1 
ATOM   2511 O  O   . ALA B 1 63  ? 29.31868  -4.35989  -21.26996 1.000 32.90717 ? 61  ALA B O   1 
ATOM   2512 C  CB  . ALA B 1 63  ? 27.64742  -1.55004  -20.69538 1.000 27.71830 ? 61  ALA B CB  1 
ATOM   2513 N  N   . TRP B 1 64  ? 29.99754  -2.66702  -22.59314 1.000 30.11728 ? 62  TRP B N   1 
ATOM   2514 C  CA  . TRP B 1 64  ? 30.31473  -3.59950  -23.68219 1.000 32.29572 ? 62  TRP B CA  1 
ATOM   2515 C  C   . TRP B 1 64  ? 31.53801  -4.46890  -23.38662 1.000 35.02638 ? 62  TRP B C   1 
ATOM   2516 O  O   . TRP B 1 64  ? 31.57882  -5.62997  -23.80472 1.000 33.55563 ? 62  TRP B O   1 
ATOM   2517 C  CB  . TRP B 1 64  ? 30.54176  -2.85656  -24.99128 1.000 28.91297 ? 62  TRP B CB  1 
ATOM   2518 C  CG  . TRP B 1 64  ? 29.31079  -2.55530  -25.70532 1.000 31.24065 ? 62  TRP B CG  1 
ATOM   2519 C  CD1 . TRP B 1 64  ? 28.11524  -3.21297  -25.60375 1.000 30.98526 ? 62  TRP B CD1 1 
ATOM   2520 C  CD2 . TRP B 1 64  ? 29.10168  -1.47291  -26.61695 1.000 32.66596 ? 62  TRP B CD2 1 
ATOM   2521 N  NE1 . TRP B 1 64  ? 27.18161  -2.61421  -26.42608 1.000 32.01606 ? 62  TRP B NE1 1 
ATOM   2522 C  CE2 . TRP B 1 64  ? 27.76392  -1.54409  -27.05494 1.000 30.72987 ? 62  TRP B CE2 1 
ATOM   2523 C  CE3 . TRP B 1 64  ? 29.92367  -0.46795  -27.12135 1.000 30.49072 ? 62  TRP B CE3 1 
ATOM   2524 C  CZ2 . TRP B 1 64  ? 27.23758  -0.65925  -27.99614 1.000 27.23279 ? 62  TRP B CZ2 1 
ATOM   2525 C  CZ3 . TRP B 1 64  ? 29.40112  0.41120   -28.04169 1.000 35.21517 ? 62  TRP B CZ3 1 
ATOM   2526 C  CH2 . TRP B 1 64  ? 28.05397  0.31567   -28.45786 1.000 32.76533 ? 62  TRP B CH2 1 
ATOM   2527 N  N   . VAL B 1 65  ? 32.54984  -3.94230  -22.69300 1.000 35.68756 ? 63  VAL B N   1 
ATOM   2528 C  CA  . VAL B 1 65  ? 33.67752  -4.80329  -22.32605 1.000 37.46737 ? 63  VAL B CA  1 
ATOM   2529 C  C   . VAL B 1 65  ? 33.22410  -5.91109  -21.37572 1.000 37.00514 ? 63  VAL B C   1 
ATOM   2530 O  O   . VAL B 1 65  ? 33.71867  -7.04787  -21.43779 1.000 38.70932 ? 63  VAL B O   1 
ATOM   2531 C  CB  . VAL B 1 65  ? 34.83826  -3.95651  -21.74475 1.000 42.47700 ? 63  VAL B CB  1 
ATOM   2532 C  CG1 . VAL B 1 65  ? 34.52822  -3.42169  -20.30819 1.000 37.57785 ? 63  VAL B CG1 1 
ATOM   2533 C  CG2 . VAL B 1 65  ? 36.15157  -4.75751  -21.78113 1.000 40.76735 ? 63  VAL B CG2 1 
ATOM   2534 N  N   . GLN B 1 66  ? 32.25024  -5.62526  -20.51736 1.000 36.76582 ? 64  GLN B N   1 
ATOM   2535 C  CA  . GLN B 1 66  ? 31.71916  -6.67207  -19.66777 1.000 36.40293 ? 64  GLN B CA  1 
ATOM   2536 C  C   . GLN B 1 66  ? 30.88202  -7.65975  -20.47867 1.000 35.91820 ? 64  GLN B C   1 
ATOM   2537 O  O   . GLN B 1 66  ? 30.98467  -8.87117  -20.26339 1.000 33.68305 ? 64  GLN B O   1 
ATOM   2538 C  CB  . GLN B 1 66  ? 30.92968  -6.06720  -18.50065 1.000 35.12184 ? 64  GLN B CB  1 
ATOM   2539 C  CG  . GLN B 1 66  ? 30.74324  -7.03068  -17.33018 1.000 34.64630 ? 64  GLN B CG  1 
ATOM   2540 C  CD  . GLN B 1 66  ? 32.04232  -7.61835  -16.78901 1.000 36.91969 ? 64  GLN B CD  1 
ATOM   2541 O  OE1 . GLN B 1 66  ? 33.06245  -6.92918  -16.70239 1.000 36.06128 ? 64  GLN B OE1 1 
ATOM   2542 N  NE2 . GLN B 1 66  ? 31.99811  -8.90228  -16.39352 1.000 37.00708 ? 64  GLN B NE2 1 
ATOM   2543 N  N   . VAL B 1 67  ? 30.10481  -7.17647  -21.46072 1.000 32.85138 ? 65  VAL B N   1 
ATOM   2544 C  CA  . VAL B 1 67  ? 29.38076  -8.10205  -22.34309 1.000 36.45630 ? 65  VAL B CA  1 
ATOM   2545 C  C   . VAL B 1 67  ? 30.34686  -9.10346  -22.97069 1.000 33.81721 ? 65  VAL B C   1 
ATOM   2546 O  O   . VAL B 1 67  ? 30.10356  -10.31211 -22.97116 1.000 34.94854 ? 65  VAL B O   1 
ATOM   2547 C  CB  . VAL B 1 67  ? 28.60983  -7.33525  -23.43449 1.000 37.65612 ? 65  VAL B CB  1 
ATOM   2548 C  CG1 . VAL B 1 67  ? 28.14536  -8.32400  -24.55759 1.000 31.40918 ? 65  VAL B CG1 1 
ATOM   2549 C  CG2 . VAL B 1 67  ? 27.41835  -6.62666  -22.83222 1.000 35.59394 ? 65  VAL B CG2 1 
ATOM   2550 N  N   . HIS B 1 68  ? 31.44762  -8.59519  -23.52764 1.000 34.15618 ? 66  HIS B N   1 
ATOM   2551 C  CA  . HIS B 1 68  ? 32.46496  -9.43123  -24.15563 1.000 33.41189 ? 66  HIS B CA  1 
ATOM   2552 C  C   . HIS B 1 68  ? 33.02596  -10.44637 -23.17141 1.000 36.17318 ? 66  HIS B C   1 
ATOM   2553 O  O   . HIS B 1 68  ? 33.22790  -11.61404 -23.51814 1.000 35.63388 ? 66  HIS B O   1 
ATOM   2554 C  CB  . HIS B 1 68  ? 33.58889  -8.54543  -24.70199 1.000 33.51266 ? 66  HIS B CB  1 
ATOM   2555 C  CG  . HIS B 1 68  ? 34.60493  -9.26911  -25.53667 1.000 36.66035 ? 66  HIS B CG  1 
ATOM   2556 N  ND1 . HIS B 1 68  ? 35.65302  -9.97940  -24.98772 1.000 36.95153 ? 66  HIS B ND1 1 
ATOM   2557 C  CD2 . HIS B 1 68  ? 34.75820  -9.35514  -26.88175 1.000 38.79858 ? 66  HIS B CD2 1 
ATOM   2558 C  CE1 . HIS B 1 68  ? 36.40405  -10.47388 -25.95765 1.000 37.70728 ? 66  HIS B CE1 1 
ATOM   2559 N  NE2 . HIS B 1 68  ? 35.87927  -10.11918 -27.11644 1.000 35.24904 ? 66  HIS B NE2 1 
ATOM   2560 N  N   . TYR B 1 69  ? 33.29965  -10.00630 -21.94743 1.000 36.72008 ? 67  TYR B N   1 
ATOM   2561 C  CA  . TYR B 1 69  ? 33.82063  -10.89827 -20.92247 1.000 34.80537 ? 67  TYR B CA  1 
ATOM   2562 C  C   . TYR B 1 69  ? 32.84657  -12.03664 -20.62375 1.000 37.09321 ? 67  TYR B C   1 
ATOM   2563 O  O   . TYR B 1 69  ? 33.25434  -13.20008 -20.52042 1.000 36.48600 ? 67  TYR B O   1 
ATOM   2564 C  CB  . TYR B 1 69  ? 34.12510  -10.07565 -19.67359 1.000 34.84414 ? 67  TYR B CB  1 
ATOM   2565 C  CG  . TYR B 1 69  ? 34.89293  -10.80217 -18.60493 1.000 38.19360 ? 67  TYR B CG  1 
ATOM   2566 C  CD1 . TYR B 1 69  ? 36.29372  -10.87300 -18.63700 1.000 37.71531 ? 67  TYR B CD1 1 
ATOM   2567 C  CD2 . TYR B 1 69  ? 34.22282  -11.40647 -17.55555 1.000 33.99240 ? 67  TYR B CD2 1 
ATOM   2568 C  CE1 . TYR B 1 69  ? 36.98325  -11.53476 -17.63578 1.000 40.46555 ? 67  TYR B CE1 1 
ATOM   2569 C  CE2 . TYR B 1 69  ? 34.89489  -12.07438 -16.56838 1.000 38.08225 ? 67  TYR B CE2 1 
ATOM   2570 C  CZ  . TYR B 1 69  ? 36.26880  -12.13642 -16.60510 1.000 41.26637 ? 67  TYR B CZ  1 
ATOM   2571 O  OH  . TYR B 1 69  ? 36.90330  -12.80827 -15.59474 1.000 39.82763 ? 67  TYR B OH  1 
ATOM   2572 N  N   . GLU B 1 70  ? 31.55154  -11.73203 -20.48364 1.000 34.56145 ? 68  GLU B N   1 
ATOM   2573 C  CA  . GLU B 1 70  ? 30.60522  -12.80623 -20.19973 1.000 34.55547 ? 68  GLU B CA  1 
ATOM   2574 C  C   . GLU B 1 70  ? 30.32601  -13.66389 -21.42968 1.000 33.24662 ? 68  GLU B C   1 
ATOM   2575 O  O   . GLU B 1 70  ? 30.06950  -14.85506 -21.28626 1.000 33.73234 ? 68  GLU B O   1 
ATOM   2576 C  CB  . GLU B 1 70  ? 29.29018  -12.25843 -19.62614 1.000 36.60923 ? 68  GLU B CB  1 
ATOM   2577 C  CG  . GLU B 1 70  ? 29.43812  -11.23159 -18.49696 1.000 32.94794 ? 68  GLU B CG  1 
ATOM   2578 C  CD  . GLU B 1 70  ? 29.98395  -11.83302 -17.21436 1.000 39.14710 ? 68  GLU B CD  1 
ATOM   2579 O  OE1 . GLU B 1 70  ? 30.36312  -13.03542 -17.21024 1.000 39.42470 ? 68  GLU B OE1 1 
ATOM   2580 O  OE2 . GLU B 1 70  ? 30.04560  -11.09480 -16.20961 1.000 38.20325 ? 68  GLU B OE2 1 
ATOM   2581 N  N   . LEU B 1 71  ? 30.38535  -13.10310 -22.63819 1.000 32.78565 ? 69  LEU B N   1 
ATOM   2582 C  CA  . LEU B 1 71  ? 30.21856  -13.94425 -23.82737 1.000 33.71495 ? 69  LEU B CA  1 
ATOM   2583 C  C   . LEU B 1 71  ? 31.37088  -14.94134 -23.96670 1.000 34.46459 ? 69  LEU B C   1 
ATOM   2584 O  O   . LEU B 1 71  ? 31.17878  -16.06840 -24.44413 1.000 35.12349 ? 69  LEU B O   1 
ATOM   2585 C  CB  . LEU B 1 71  ? 30.10092  -13.05379 -25.07286 1.000 28.67730 ? 69  LEU B CB  1 
ATOM   2586 C  CG  . LEU B 1 71  ? 28.75845  -12.31043 -25.27813 1.000 30.05089 ? 69  LEU B CG  1 
ATOM   2587 C  CD1 . LEU B 1 71  ? 28.76596  -11.61823 -26.60906 1.000 29.78617 ? 69  LEU B CD1 1 
ATOM   2588 C  CD2 . LEU B 1 71  ? 27.57303  -13.25329 -25.23172 1.000 31.00416 ? 69  LEU B CD2 1 
ATOM   2589 N  N   . ARG B 1 72  ? 32.58877  -14.52935 -23.60201 1.000 35.38002 ? 70  ARG B N   1 
ATOM   2590 C  CA  . ARG B 1 72  ? 33.70565  -15.47195 -23.57367 1.000 37.39135 ? 70  ARG B CA  1 
ATOM   2591 C  C   . ARG B 1 72  ? 33.40103  -16.62327 -22.63584 1.000 35.65241 ? 70  ARG B C   1 
ATOM   2592 O  O   . ARG B 1 72  ? 33.55022  -17.79593 -22.99577 1.000 36.99061 ? 70  ARG B O   1 
ATOM   2593 C  CB  . ARG B 1 72  ? 34.99125  -14.76557 -23.13326 1.000 40.48749 ? 70  ARG B CB  1 
ATOM   2594 C  CG  . ARG B 1 72  ? 35.69801  -14.00243 -24.21870 1.000 39.02596 ? 70  ARG B CG  1 
ATOM   2595 C  CD  . ARG B 1 72  ? 36.74057  -13.07033 -23.62014 1.000 42.70521 ? 70  ARG B CD  1 
ATOM   2596 N  NE  . ARG B 1 72  ? 37.74190  -13.80742 -22.85583 1.000 45.84656 ? 70  ARG B NE  1 
ATOM   2597 C  CZ  . ARG B 1 72  ? 38.53683  -13.27483 -21.93410 1.000 48.42158 ? 70  ARG B CZ  1 
ATOM   2598 N  NH1 . ARG B 1 72  ? 38.47623  -11.98641 -21.62041 1.000 38.58961 ? 70  ARG B NH1 1 
ATOM   2599 N  NH2 . ARG B 1 72  ? 39.42305  -14.05303 -21.31626 1.000 44.76267 ? 70  ARG B NH2 1 
ATOM   2600 N  N   . ARG B 1 73  ? 32.95226  -16.29825 -21.42465 1.000 36.27719 ? 71  ARG B N   1 
ATOM   2601 C  CA  . ARG B 1 73  ? 32.53511  -17.32172 -20.48128 1.000 33.84158 ? 71  ARG B CA  1 
ATOM   2602 C  C   . ARG B 1 73  ? 31.43232  -18.20252 -21.05967 1.000 37.89412 ? 71  ARG B C   1 
ATOM   2603 O  O   . ARG B 1 73  ? 31.41687  -19.42179 -20.82722 1.000 35.40829 ? 71  ARG B O   1 
ATOM   2604 C  CB  . ARG B 1 73  ? 32.06855  -16.67148 -19.18364 1.000 36.27882 ? 71  ARG B CB  1 
ATOM   2605 C  CG  . ARG B 1 73  ? 33.19131  -16.10845 -18.36354 1.000 36.74898 ? 71  ARG B CG  1 
ATOM   2606 C  CD  . ARG B 1 73  ? 32.64748  -15.37136 -17.18054 1.000 36.89878 ? 71  ARG B CD  1 
ATOM   2607 N  NE  . ARG B 1 73  ? 32.09493  -16.26176 -16.16777 1.000 34.73410 ? 71  ARG B NE  1 
ATOM   2608 C  CZ  . ARG B 1 73  ? 31.46291  -15.83162 -15.08568 1.000 40.15835 ? 71  ARG B CZ  1 
ATOM   2609 N  NH1 . ARG B 1 73  ? 31.21576  -14.53408 -14.89448 1.000 37.63248 ? 71  ARG B NH1 1 
ATOM   2610 N  NH2 . ARG B 1 73  ? 31.06225  -16.71580 -14.17328 1.000 36.95167 ? 71  ARG B NH2 1 
ATOM   2611 N  N   . ALA B 1 74  ? 30.49277  -17.61916 -21.81193 1.000 32.47441 ? 72  ALA B N   1 
ATOM   2612 C  CA  . ALA B 1 74  ? 29.43241  -18.46788 -22.36094 1.000 36.64908 ? 72  ALA B CA  1 
ATOM   2613 C  C   . ALA B 1 74  ? 29.97082  -19.44993 -23.40713 1.000 34.07643 ? 72  ALA B C   1 
ATOM   2614 O  O   . ALA B 1 74  ? 29.47034  -20.57882 -23.50145 1.000 35.51499 ? 72  ALA B O   1 
ATOM   2615 C  CB  . ALA B 1 74  ? 28.31165  -17.61405 -22.95194 1.000 32.51461 ? 72  ALA B CB  1 
ATOM   2616 N  N   . ILE B 1 75  ? 30.97369  -19.04061 -24.20073 1.000 34.96840 ? 73  ILE B N   1 
ATOM   2617 C  CA  . ILE B 1 75  ? 31.60721  -19.96966 -25.14160 1.000 37.52922 ? 73  ILE B CA  1 
ATOM   2618 C  C   . ILE B 1 75  ? 32.21018  -21.15160 -24.38169 1.000 38.65636 ? 73  ILE B C   1 
ATOM   2619 O  O   . ILE B 1 75  ? 32.06794  -22.31651 -24.78362 1.000 37.53080 ? 73  ILE B O   1 
ATOM   2620 C  CB  . ILE B 1 75  ? 32.67820  -19.24563 -25.98532 1.000 38.29561 ? 73  ILE B CB  1 
ATOM   2621 C  CG1 . ILE B 1 75  ? 32.05349  -18.36352 -27.07796 1.000 37.77700 ? 73  ILE B CG1 1 
ATOM   2622 C  CG2 . ILE B 1 75  ? 33.65590  -20.27446 -26.61566 1.000 37.69380 ? 73  ILE B CG2 1 
ATOM   2623 C  CD1 . ILE B 1 75  ? 33.00375  -17.21548 -27.60011 1.000 35.73778 ? 73  ILE B CD1 1 
ATOM   2624 N  N   . GLY B 1 76  ? 32.88844  -20.86514 -23.26800 1.000 37.58309 ? 74  GLY B N   1 
ATOM   2625 C  CA  . GLY B 1 76  ? 33.48198  -21.92675 -22.47638 1.000 37.51017 ? 74  GLY B CA  1 
ATOM   2626 C  C   . GLY B 1 76  ? 32.44798  -22.88747 -21.93568 1.000 41.95896 ? 74  GLY B C   1 
ATOM   2627 O  O   . GLY B 1 76  ? 32.66376  -24.10567 -21.92001 1.000 42.76545 ? 74  GLY B O   1 
ATOM   2628 N  N   . HIS B 1 77  ? 31.30737  -22.35371 -21.48388 1.000 39.91893 ? 75  HIS B N   1 
ATOM   2629 C  CA  . HIS B 1 77  ? 30.23473  -23.19888 -20.97850 1.000 38.03088 ? 75  HIS B CA  1 
ATOM   2630 C  C   . HIS B 1 77  ? 29.66487  -24.08783 -22.08010 1.000 37.58826 ? 75  HIS B C   1 
ATOM   2631 O  O   . HIS B 1 77  ? 29.53054  -25.30479 -21.90857 1.000 38.67187 ? 75  HIS B O   1 
ATOM   2632 C  CB  . HIS B 1 77  ? 29.14368  -22.32787 -20.36171 1.000 39.19852 ? 75  HIS B CB  1 
ATOM   2633 C  CG  . HIS B 1 77  ? 29.53982  -21.71939 -19.05308 1.000 42.58825 ? 75  HIS B CG  1 
ATOM   2634 N  ND1 . HIS B 1 77  ? 30.20966  -22.42867 -18.07665 1.000 42.40614 ? 75  HIS B ND1 1 
ATOM   2635 C  CD2 . HIS B 1 77  ? 29.38674  -20.46268 -18.57031 1.000 37.09447 ? 75  HIS B CD2 1 
ATOM   2636 C  CE1 . HIS B 1 77  ? 30.43346  -21.63544 -17.04110 1.000 40.28270 ? 75  HIS B CE1 1 
ATOM   2637 N  NE2 . HIS B 1 77  ? 29.95491  -20.43604 -17.32110 1.000 37.59389 ? 75  HIS B NE2 1 
ATOM   2638 N  N   . LEU B 1 78  ? 29.35498  -23.49622 -23.23231 1.000 36.80187 ? 76  LEU B N   1 
ATOM   2639 C  CA  . LEU B 1 78  ? 28.73277  -24.25380 -24.31028 1.000 38.33365 ? 76  LEU B CA  1 
ATOM   2640 C  C   . LEU B 1 78  ? 29.65207  -25.35967 -24.79779 1.000 37.25580 ? 76  LEU B C   1 
ATOM   2641 O  O   . LEU B 1 78  ? 29.20452  -26.48482 -25.04781 1.000 38.61310 ? 76  LEU B O   1 
ATOM   2642 C  CB  . LEU B 1 78  ? 28.36134  -23.30979 -25.45516 1.000 34.26295 ? 76  LEU B CB  1 
ATOM   2643 C  CG  . LEU B 1 78  ? 27.16089  -22.41102 -25.15182 1.000 33.82487 ? 76  LEU B CG  1 
ATOM   2644 C  CD1 . LEU B 1 78  ? 27.05209  -21.35163 -26.26119 1.000 34.02343 ? 76  LEU B CD1 1 
ATOM   2645 C  CD2 . LEU B 1 78  ? 25.87906  -23.24350 -25.03050 1.000 30.46460 ? 76  LEU B CD2 1 
ATOM   2646 N  N   . ASP B 1 79  ? 30.94367  -25.05103 -24.94200 1.000 37.92308 ? 77  ASP B N   1 
ATOM   2647 C  CA  . ASP B 1 79  ? 31.92441  -26.03524 -25.38902 1.000 39.17642 ? 77  ASP B CA  1 
ATOM   2648 C  C   . ASP B 1 79  ? 32.03270  -27.22997 -24.44470 1.000 41.59389 ? 77  ASP B C   1 
ATOM   2649 O  O   . ASP B 1 79  ? 32.44370  -28.31010 -24.88289 1.000 44.10313 ? 77  ASP B O   1 
ATOM   2650 C  CB  . ASP B 1 79  ? 33.29066  -25.36216 -25.53941 1.000 38.65333 ? 77  ASP B CB  1 
ATOM   2651 C  CG  . ASP B 1 79  ? 33.42918  -24.57497 -26.83972 1.000 38.98860 ? 77  ASP B CG  1 
ATOM   2652 O  OD1 . ASP B 1 79  ? 32.52461  -24.61867 -27.70586 1.000 37.98109 ? 77  ASP B OD1 1 
ATOM   2653 O  OD2 . ASP B 1 79  ? 34.46058  -23.89540 -26.98727 1.000 38.40546 ? 77  ASP B OD2 1 
ATOM   2654 N  N   . GLU B 1 80  ? 31.67836  -27.06756 -23.16640 1.000 38.38028 ? 78  GLU B N   1 
ATOM   2655 C  CA  . GLU B 1 80  ? 31.63305  -28.16744 -22.21056 1.000 37.76559 ? 78  GLU B CA  1 
ATOM   2656 C  C   . GLU B 1 80  ? 30.21953  -28.66293 -21.92651 1.000 40.71116 ? 78  GLU B C   1 
ATOM   2657 O  O   . GLU B 1 80  ? 30.02369  -29.41224 -20.96345 1.000 42.27445 ? 78  GLU B O   1 
ATOM   2658 C  CB  . GLU B 1 80  ? 32.30419  -27.75947 -20.90565 1.000 36.13129 ? 78  GLU B CB  1 
ATOM   2659 C  CG  . GLU B 1 80  ? 33.79047  -27.47987 -21.05594 1.000 43.69574 ? 78  GLU B CG  1 
ATOM   2660 C  CD  . GLU B 1 80  ? 34.53095  -28.66417 -21.66168 1.000 50.80299 ? 78  GLU B CD  1 
ATOM   2661 O  OE1 . GLU B 1 80  ? 34.42621  -29.76215 -21.07925 1.000 50.42320 ? 78  GLU B OE1 1 
ATOM   2662 O  OE2 . GLU B 1 80  ? 35.18297  -28.51077 -22.72357 1.000 54.23380 ? 78  GLU B OE2 1 
ATOM   2663 N  N   . ASP B 1 81  ? 29.23751  -28.28023 -22.74730 1.000 39.92523 ? 79  ASP B N   1 
ATOM   2664 C  CA  . ASP B 1 81  ? 27.82596  -28.66978 -22.57817 1.000 38.81406 ? 79  ASP B CA  1 
ATOM   2665 C  C   . ASP B 1 81  ? 27.24943  -28.24493 -21.22498 1.000 40.21979 ? 79  ASP B C   1 
ATOM   2666 O  O   . ASP B 1 81  ? 26.29016  -28.84128 -20.72885 1.000 38.25045 ? 79  ASP B O   1 
ATOM   2667 C  CB  . ASP B 1 81  ? 27.63044  -30.16832 -22.79700 1.000 40.59035 ? 79  ASP B CB  1 
ATOM   2668 C  CG  . ASP B 1 81  ? 28.13824  -30.62088 -24.15729 1.000 44.39486 ? 79  ASP B CG  1 
ATOM   2669 O  OD1 . ASP B 1 81  ? 27.75113  -30.02626 -25.19444 1.000 43.38589 ? 79  ASP B OD1 1 
ATOM   2670 O  OD2 . ASP B 1 81  ? 28.95996  -31.54803 -24.18455 1.000 46.94101 ? 79  ASP B OD2 1 
ATOM   2671 N  N   . ARG B 1 82  ? 27.78218  -27.17644 -20.63008 1.000 41.36382 ? 80  ARG B N   1 
ATOM   2672 C  CA  . ARG B 1 82  ? 27.21261  -26.63433 -19.39198 1.000 39.78060 ? 80  ARG B CA  1 
ATOM   2673 C  C   . ARG B 1 82  ? 26.14135  -25.60933 -19.77810 1.000 34.88901 ? 80  ARG B C   1 
ATOM   2674 O  O   . ARG B 1 82  ? 26.34306  -24.39708 -19.71557 1.000 36.86300 ? 80  ARG B O   1 
ATOM   2675 C  CB  . ARG B 1 82  ? 28.31201  -26.03826 -18.51446 1.000 40.38282 ? 80  ARG B CB  1 
ATOM   2676 C  CG  . ARG B 1 82  ? 29.54404  -26.94764 -18.33309 1.000 43.35727 ? 80  ARG B CG  1 
ATOM   2677 C  CD  . ARG B 1 82  ? 30.56025  -26.37161 -17.33137 1.000 41.22864 ? 80  ARG B CD  1 
ATOM   2678 N  NE  . ARG B 1 82  ? 31.23509  -25.17649 -17.83692 1.000 44.23717 ? 80  ARG B NE  1 
ATOM   2679 C  CZ  . ARG B 1 82  ? 32.51886  -25.12164 -18.17684 1.000 44.04002 ? 80  ARG B CZ  1 
ATOM   2680 N  NH1 . ARG B 1 82  ? 33.30804  -26.18304 -18.07720 1.000 44.03274 ? 80  ARG B NH1 1 
ATOM   2681 N  NH2 . ARG B 1 82  ? 33.03057  -23.96974 -18.60865 1.000 41.74966 ? 80  ARG B NH2 1 
ATOM   2682 N  N   . TYR B 1 83  ? 24.98203  -26.12183 -20.20478 1.000 34.71987 ? 81  TYR B N   1 
ATOM   2683 C  CA  . TYR B 1 83  ? 23.93916  -25.26335 -20.78072 1.000 36.90998 ? 81  TYR B CA  1 
ATOM   2684 C  C   . TYR B 1 83  ? 23.41451  -24.26222 -19.76205 1.000 35.01994 ? 81  TYR B C   1 
ATOM   2685 O  O   . TYR B 1 83  ? 23.25289  -23.07514 -20.06094 1.000 34.14395 ? 81  TYR B O   1 
ATOM   2686 C  CB  . TYR B 1 83  ? 22.76584  -26.11515 -21.28094 1.000 36.01418 ? 81  TYR B CB  1 
ATOM   2687 C  CG  . TYR B 1 83  ? 23.11943  -27.31699 -22.12278 1.000 36.47652 ? 81  TYR B CG  1 
ATOM   2688 C  CD1 . TYR B 1 83  ? 23.91867  -27.19712 -23.24480 1.000 39.12814 ? 81  TYR B CD1 1 
ATOM   2689 C  CD2 . TYR B 1 83  ? 22.62582  -28.58438 -21.79494 1.000 39.58123 ? 81  TYR B CD2 1 
ATOM   2690 C  CE1 . TYR B 1 83  ? 24.23010  -28.30863 -24.02662 1.000 38.61089 ? 81  TYR B CE1 1 
ATOM   2691 C  CE2 . TYR B 1 83  ? 22.94280  -29.69294 -22.55675 1.000 41.27016 ? 81  TYR B CE2 1 
ATOM   2692 C  CZ  . TYR B 1 83  ? 23.73832  -29.54330 -23.67602 1.000 42.48289 ? 81  TYR B CZ  1 
ATOM   2693 O  OH  . TYR B 1 83  ? 24.05006  -30.64360 -24.45046 1.000 42.77763 ? 81  TYR B OH  1 
ATOM   2694 N  N   . HIS B 1 84  ? 23.07065  -24.75283 -18.56973 1.000 33.24255 ? 82  HIS B N   1 
ATOM   2695 C  CA  . HIS B 1 84  ? 22.51593  -23.90589 -17.53001 1.000 32.53441 ? 82  HIS B CA  1 
ATOM   2696 C  C   . HIS B 1 84  ? 23.44065  -22.74376 -17.22993 1.000 38.20313 ? 82  HIS B C   1 
ATOM   2697 O  O   . HIS B 1 84  ? 22.99512  -21.59548 -17.07901 1.000 34.14055 ? 82  HIS B O   1 
ATOM   2698 C  CB  . HIS B 1 84  ? 22.27471  -24.73461 -16.26110 1.000 38.53162 ? 82  HIS B CB  1 
ATOM   2699 C  CG  . HIS B 1 84  ? 21.27662  -25.83559 -16.43839 1.000 36.28599 ? 82  HIS B CG  1 
ATOM   2700 N  ND1 . HIS B 1 84  ? 21.62950  -27.09879 -16.86880 1.000 42.11926 ? 82  HIS B ND1 1 
ATOM   2701 C  CD2 . HIS B 1 84  ? 19.93515  -25.86608 -16.24476 1.000 38.13358 ? 82  HIS B CD2 1 
ATOM   2702 C  CE1 . HIS B 1 84  ? 20.55112  -27.86128 -16.93388 1.000 39.60146 ? 82  HIS B CE1 1 
ATOM   2703 N  NE2 . HIS B 1 84  ? 19.50780  -27.13587 -16.56500 1.000 41.98110 ? 82  HIS B NE2 1 
ATOM   2704 N  N   . GLN B 1 85  ? 24.73655  -23.01646 -17.14626 1.000 35.38239 ? 83  GLN B N   1 
ATOM   2705 C  CA  . GLN B 1 85  ? 25.66168  -21.94277 -16.83777 1.000 36.01350 ? 83  GLN B CA  1 
ATOM   2706 C  C   . GLN B 1 85  ? 25.79359  -20.97037 -17.99833 1.000 36.61285 ? 83  GLN B C   1 
ATOM   2707 O  O   . GLN B 1 85  ? 25.97441  -19.77283 -17.76983 1.000 37.12322 ? 83  GLN B O   1 
ATOM   2708 C  CB  . GLN B 1 85  ? 27.01250  -22.52665 -16.43647 1.000 38.70104 ? 83  GLN B CB  1 
ATOM   2709 C  CG  . GLN B 1 85  ? 26.91347  -23.29925 -15.11546 1.000 36.98662 ? 83  GLN B CG  1 
ATOM   2710 C  CD  . GLN B 1 85  ? 28.05844  -24.24522 -14.90742 1.000 42.89379 ? 83  GLN B CD  1 
ATOM   2711 O  OE1 . GLN B 1 85  ? 27.99273  -25.42626 -15.27216 1.000 42.40742 ? 83  GLN B OE1 1 
ATOM   2712 N  NE2 . GLN B 1 85  ? 29.13397  -23.72935 -14.32194 1.000 40.69222 ? 83  GLN B NE2 1 
ATOM   2713 N  N   . ALA B 1 86  ? 25.66462  -21.46156 -19.23709 1.000 33.46265 ? 84  ALA B N   1 
ATOM   2714 C  CA  . ALA B 1 86  ? 25.66861  -20.58530 -20.40171 1.000 35.35871 ? 84  ALA B CA  1 
ATOM   2715 C  C   . ALA B 1 86  ? 24.48420  -19.61399 -20.38504 1.000 35.10303 ? 84  ALA B C   1 
ATOM   2716 O  O   . ALA B 1 86  ? 24.63494  -18.44316 -20.76303 1.000 35.81196 ? 84  ALA B O   1 
ATOM   2717 C  CB  . ALA B 1 86  ? 25.66932  -21.43705 -21.68319 1.000 36.36551 ? 84  ALA B CB  1 
ATOM   2718 N  N   . VAL B 1 87  ? 23.30110  -20.07076 -19.94159 1.000 35.72729 ? 85  VAL B N   1 
ATOM   2719 C  CA  . VAL B 1 87  ? 22.12204  -19.19576 -19.93489 1.000 34.67000 ? 85  VAL B CA  1 
ATOM   2720 C  C   . VAL B 1 87  ? 22.39152  -17.92993 -19.11668 1.000 37.17025 ? 85  VAL B C   1 
ATOM   2721 O  O   . VAL B 1 87  ? 22.06730  -16.80621 -19.53987 1.000 32.82606 ? 85  VAL B O   1 
ATOM   2722 C  CB  . VAL B 1 87  ? 20.88530  -19.94235 -19.39928 1.000 36.90101 ? 85  VAL B CB  1 
ATOM   2723 C  CG1 . VAL B 1 87  ? 19.73146  -18.96894 -19.22067 1.000 37.85382 ? 85  VAL B CG1 1 
ATOM   2724 C  CG2 . VAL B 1 87  ? 20.46716  -21.08226 -20.33610 1.000 32.77756 ? 85  VAL B CG2 1 
ATOM   2725 N  N   . ARG B 1 88  ? 22.97896  -18.09850 -17.92511 1.000 35.83323 ? 86  ARG B N   1 
ATOM   2726 C  CA  . ARG B 1 88  ? 23.22020  -16.96469 -17.03481 1.000 34.88322 ? 86  ARG B CA  1 
ATOM   2727 C  C   . ARG B 1 88  ? 24.13643  -15.92141 -17.66137 1.000 36.34506 ? 86  ARG B C   1 
ATOM   2728 O  O   . ARG B 1 88  ? 23.96067  -14.71151 -17.43988 1.000 34.54004 ? 86  ARG B O   1 
ATOM   2729 C  CB  . ARG B 1 88  ? 23.81078  -17.45492 -15.71865 1.000 34.18441 ? 86  ARG B CB  1 
ATOM   2730 C  CG  . ARG B 1 88  ? 22.86734  -18.33993 -14.92876 1.000 34.79216 ? 86  ARG B CG  1 
ATOM   2731 C  CD  . ARG B 1 88  ? 23.37522  -18.51561 -13.50215 1.000 36.36514 ? 86  ARG B CD  1 
ATOM   2732 N  NE  . ARG B 1 88  ? 22.64710  -19.56472 -12.79436 1.000 36.91030 ? 86  ARG B NE  1 
ATOM   2733 C  CZ  . ARG B 1 88  ? 23.03307  -20.83538 -12.71092 1.000 38.73814 ? 86  ARG B CZ  1 
ATOM   2734 N  NH1 . ARG B 1 88  ? 24.14859  -21.25661 -13.27422 1.000 36.32336 ? 86  ARG B NH1 1 
ATOM   2735 N  NH2 . ARG B 1 88  ? 22.26999  -21.70798 -12.05247 1.000 36.10207 ? 86  ARG B NH2 1 
ATOM   2736 N  N   . MET B 1 89  ? 25.15631  -16.36409 -18.39093 1.000 32.78643 ? 87  MET B N   1 
ATOM   2737 C  CA  . MET B 1 89  ? 26.04074  -15.42046 -19.06676 1.000 36.36145 ? 87  MET B CA  1 
ATOM   2738 C  C   . MET B 1 89  ? 25.29778  -14.59355 -20.10847 1.000 33.98251 ? 87  MET B C   1 
ATOM   2739 O  O   . MET B 1 89  ? 25.55024  -13.39527 -20.24090 1.000 31.77287 ? 87  MET B O   1 
ATOM   2740 C  CB  . MET B 1 89  ? 27.21321  -16.18155 -19.68494 1.000 33.03588 ? 87  MET B CB  1 
ATOM   2741 C  CG  . MET B 1 89  ? 28.02165  -16.95868 -18.66751 1.000 38.60422 ? 87  MET B CG  1 
ATOM   2742 S  SD  . MET B 1 89  ? 28.60798  -15.90275 -17.34666 1.000 51.33621 ? 87  MET B SD  1 
ATOM   2743 C  CE  . MET B 1 89  ? 27.60914  -16.33823 -15.91812 1.000 39.66744 ? 87  MET B CE  1 
ATOM   2744 N  N   . PHE B 1 90  ? 24.39431  -15.21933 -20.86326 1.000 34.86197 ? 88  PHE B N   1 
ATOM   2745 C  CA  . PHE B 1 90  ? 23.65383  -14.49021 -21.88478 1.000 33.79561 ? 88  PHE B CA  1 
ATOM   2746 C  C   . PHE B 1 90  ? 22.64419  -13.53980 -21.24419 1.000 33.75694 ? 88  PHE B C   1 
ATOM   2747 O  O   . PHE B 1 90  ? 22.42070  -12.43144 -21.74260 1.000 31.65064 ? 88  PHE B O   1 
ATOM   2748 C  CB  . PHE B 1 90  ? 22.94380  -15.46888 -22.83054 1.000 34.49723 ? 88  PHE B CB  1 
ATOM   2749 C  CG  . PHE B 1 90  ? 23.87314  -16.20085 -23.79166 1.000 34.38459 ? 88  PHE B CG  1 
ATOM   2750 C  CD1 . PHE B 1 90  ? 24.65216  -15.49669 -24.69866 1.000 34.88183 ? 88  PHE B CD1 1 
ATOM   2751 C  CD2 . PHE B 1 90  ? 23.93717  -17.60632 -23.79426 1.000 35.25658 ? 88  PHE B CD2 1 
ATOM   2752 C  CE1 . PHE B 1 90  ? 25.48785  -16.14865 -25.58062 1.000 37.19609 ? 88  PHE B CE1 1 
ATOM   2753 C  CE2 . PHE B 1 90  ? 24.76996  -18.27756 -24.66723 1.000 32.06835 ? 88  PHE B CE2 1 
ATOM   2754 C  CZ  . PHE B 1 90  ? 25.54948  -17.54487 -25.57461 1.000 34.53379 ? 88  PHE B CZ  1 
ATOM   2755 N  N   . ASP B 1 91  ? 22.02616  -13.94574 -20.13512 1.000 33.52373 ? 89  ASP B N   1 
ATOM   2756 C  CA  . ASP B 1 91  ? 21.07065  -13.04566 -19.49962 1.000 32.96035 ? 89  ASP B CA  1 
ATOM   2757 C  C   . ASP B 1 91  ? 21.78318  -11.84034 -18.92205 1.000 34.04539 ? 89  ASP B C   1 
ATOM   2758 O  O   . ASP B 1 91  ? 21.28457  -10.71124 -19.00246 1.000 29.54343 ? 89  ASP B O   1 
ATOM   2759 C  CB  . ASP B 1 91  ? 20.29009  -13.76194 -18.40162 1.000 34.30544 ? 89  ASP B CB  1 
ATOM   2760 C  CG  . ASP B 1 91  ? 19.18772  -14.67182 -18.94923 1.000 34.49641 ? 89  ASP B CG  1 
ATOM   2761 O  OD1 . ASP B 1 91  ? 18.72468  -14.49181 -20.08913 1.000 34.42444 ? 89  ASP B OD1 1 
ATOM   2762 O  OD2 . ASP B 1 91  ? 18.75969  -15.55818 -18.20602 1.000 30.87199 ? 89  ASP B OD2 1 
ATOM   2763 N  N   . ARG B 1 92  ? 22.94641  -12.06379 -18.31846 1.000 33.18483 ? 90  ARG B N   1 
ATOM   2764 C  CA  . ARG B 1 92  ? 23.72455  -10.94790 -17.79922 1.000 32.24270 ? 90  ARG B CA  1 
ATOM   2765 C  C   . ARG B 1 92  ? 24.12199  -10.00366 -18.92231 1.000 33.98124 ? 90  ARG B C   1 
ATOM   2766 O  O   . ARG B 1 92  ? 23.98530  -8.77774  -18.80900 1.000 32.73126 ? 90  ARG B O   1 
ATOM   2767 C  CB  . ARG B 1 92  ? 24.95424  -11.48834 -17.08438 1.000 33.17510 ? 90  ARG B CB  1 
ATOM   2768 C  CG  . ARG B 1 92  ? 25.63162  -10.46150 -16.22419 1.000 36.24509 ? 90  ARG B CG  1 
ATOM   2769 C  CD  . ARG B 1 92  ? 26.90929  -11.03257 -15.65232 1.000 38.07062 ? 90  ARG B CD  1 
ATOM   2770 N  NE  . ARG B 1 92  ? 26.66694  -12.12559 -14.71135 1.000 38.27425 ? 90  ARG B NE  1 
ATOM   2771 C  CZ  . ARG B 1 92  ? 27.60830  -12.64463 -13.93272 1.000 41.01352 ? 90  ARG B CZ  1 
ATOM   2772 N  NH1 . ARG B 1 92  ? 28.84028  -12.15874 -13.92985 1.000 38.99153 ? 90  ARG B NH1 1 
ATOM   2773 N  NH2 . ARG B 1 92  ? 27.31043  -13.68320 -13.14406 1.000 38.07013 ? 90  ARG B NH2 1 
ATOM   2774 N  N   . ALA B 1 93  ? 24.60592  -10.56699 -20.03038 1.000 30.49128 ? 91  ALA B N   1 
ATOM   2775 C  CA  . ALA B 1 93  ? 24.94326  -9.74566  -21.18346 1.000 30.63953 ? 91  ALA B CA  1 
ATOM   2776 C  C   . ALA B 1 93  ? 23.75123  -8.91248  -21.63811 1.000 31.37060 ? 91  ALA B C   1 
ATOM   2777 O  O   . ALA B 1 93  ? 23.91691  -7.74002  -21.97192 1.000 29.49250 ? 91  ALA B O   1 
ATOM   2778 C  CB  . ALA B 1 93  ? 25.45767  -10.62295 -22.33504 1.000 28.53894 ? 91  ALA B CB  1 
ATOM   2779 N  N   . THR B 1 94  ? 22.54989  -9.50631  -21.70886 1.000 30.09093 ? 92  THR B N   1 
ATOM   2780 C  CA  . THR B 1 94  ? 21.39035  -8.71219  -22.11757 1.000 27.72858 ? 92  THR B CA  1 
ATOM   2781 C  C   . THR B 1 94  ? 21.18097  -7.52457  -21.18068 1.000 30.09997 ? 92  THR B C   1 
ATOM   2782 O  O   . THR B 1 94  ? 20.91770  -6.40461  -21.63725 1.000 31.32745 ? 92  THR B O   1 
ATOM   2783 C  CB  . THR B 1 94  ? 20.13247  -9.58216  -22.17397 1.000 28.29072 ? 92  THR B CB  1 
ATOM   2784 O  OG1 . THR B 1 94  ? 20.35810  -10.67566 -23.07292 1.000 29.78171 ? 92  THR B OG1 1 
ATOM   2785 C  CG2 . THR B 1 94  ? 18.94050  -8.76126  -22.68295 1.000 29.10950 ? 92  THR B CG2 1 
ATOM   2786 N  N   . GLY B 1 95  ? 21.29831  -7.75016  -19.86522 1.000 27.72920 ? 93  GLY B N   1 
ATOM   2787 C  CA  . GLY B 1 95  ? 21.15659  -6.65056  -18.92077 1.000 30.14143 ? 93  GLY B CA  1 
ATOM   2788 C  C   . GLY B 1 95  ? 22.17245  -5.54625  -19.14009 1.000 31.66097 ? 93  GLY B C   1 
ATOM   2789 O  O   . GLY B 1 95  ? 21.83024  -4.36320  -19.12460 1.000 30.40280 ? 93  GLY B O   1 
ATOM   2790 N  N   . LEU B 1 96  ? 23.43533  -5.91046  -19.31868 1.000 28.34131 ? 94  LEU B N   1 
ATOM   2791 C  CA  . LEU B 1 96  ? 24.45734  -4.90957  -19.59132 1.000 30.66854 ? 94  LEU B CA  1 
ATOM   2792 C  C   . LEU B 1 96  ? 24.18150  -4.18086  -20.90244 1.000 31.47555 ? 94  LEU B C   1 
ATOM   2793 O  O   . LEU B 1 96  ? 24.42428  -2.96808  -21.01674 1.000 30.61473 ? 94  LEU B O   1 
ATOM   2794 C  CB  . LEU B 1 96  ? 25.83233  -5.57675  -19.64239 1.000 31.43964 ? 94  LEU B CB  1 
ATOM   2795 C  CG  . LEU B 1 96  ? 26.32281  -6.11203  -18.29830 1.000 33.03292 ? 94  LEU B CG  1 
ATOM   2796 C  CD1 . LEU B 1 96  ? 27.28195  -7.26874  -18.54549 1.000 32.60634 ? 94  LEU B CD1 1 
ATOM   2797 C  CD2 . LEU B 1 96  ? 27.02728  -4.99368  -17.54232 1.000 33.94530 ? 94  LEU B CD2 1 
ATOM   2798 N  N   . SER B 1 97  ? 23.69569  -4.90866  -21.90987 1.000 30.82912 ? 95  SER B N   1 
ATOM   2799 C  CA  . SER B 1 97  ? 23.30324  -4.26009  -23.15735 1.000 31.43081 ? 95  SER B CA  1 
ATOM   2800 C  C   . SER B 1 97  ? 22.21253  -3.22842  -22.90177 1.000 30.93909 ? 95  SER B C   1 
ATOM   2801 O  O   . SER B 1 97  ? 22.25660  -2.10530  -23.42812 1.000 32.54796 ? 95  SER B O   1 
ATOM   2802 C  CB  . SER B 1 97  ? 22.82043  -5.32128  -24.15333 1.000 31.20457 ? 95  SER B CB  1 
ATOM   2803 O  OG  . SER B 1 97  ? 22.43228  -4.71703  -25.37225 1.000 27.58347 ? 95  SER B OG  1 
ATOM   2804 N  N   . GLU B 1 98  ? 21.24222  -3.57368  -22.05363 1.000 32.70809 ? 96  GLU B N   1 
ATOM   2805 C  CA  . GLU B 1 98  ? 20.17428  -2.62994  -21.78036 1.000 32.25928 ? 96  GLU B CA  1 
ATOM   2806 C  C   . GLU B 1 98  ? 20.69761  -1.37623  -21.09493 1.000 34.23507 ? 96  GLU B C   1 
ATOM   2807 O  O   . GLU B 1 98  ? 20.08396  -0.31361  -21.22893 1.000 32.40840 ? 96  GLU B O   1 
ATOM   2808 C  CB  . GLU B 1 98  ? 19.06780  -3.30277  -20.95579 1.000 36.45902 ? 96  GLU B CB  1 
ATOM   2809 C  CG  . GLU B 1 98  ? 18.18953  -4.21802  -21.81584 1.000 33.62024 ? 96  GLU B CG  1 
ATOM   2810 C  CD  . GLU B 1 98  ? 17.44459  -3.43649  -22.89825 1.000 34.03614 ? 96  GLU B CD  1 
ATOM   2811 O  OE1 . GLU B 1 98  ? 16.65275  -2.56209  -22.55095 1.000 34.59984 ? 96  GLU B OE1 1 
ATOM   2812 O  OE2 . GLU B 1 98  ? 17.60999  -3.70511  -24.09440 1.000 33.46075 ? 96  GLU B OE2 1 
ATOM   2813 N  N   . VAL B 1 99  ? 21.83579  -1.45027  -20.39948 1.000 32.74209 ? 97  VAL B N   1 
ATOM   2814 C  CA  . VAL B 1 99  ? 22.43740  -0.20553  -19.91505 1.000 30.63140 ? 97  VAL B CA  1 
ATOM   2815 C  C   . VAL B 1 99  ? 22.91996  0.64832   -21.08548 1.000 33.32690 ? 97  VAL B C   1 
ATOM   2816 O  O   . VAL B 1 99  ? 22.67534  1.86076   -21.11685 1.000 32.39962 ? 97  VAL B O   1 
ATOM   2817 C  CB  . VAL B 1 99  ? 23.56105  -0.48790  -18.90615 1.000 30.90173 ? 97  VAL B CB  1 
ATOM   2818 C  CG1 . VAL B 1 99  ? 24.35434  0.75732   -18.62024 1.000 34.61491 ? 97  VAL B CG1 1 
ATOM   2819 C  CG2 . VAL B 1 99  ? 22.96498  -1.03556  -17.59695 1.000 33.57054 ? 97  VAL B CG2 1 
ATOM   2820 N  N   . THR B 1 100 ? 23.55952  0.04372   -22.09640 1.000 31.90152 ? 98  THR B N   1 
ATOM   2821 C  CA  . THR B 1 100 ? 23.97508  0.87164   -23.22719 1.000 30.18443 ? 98  THR B CA  1 
ATOM   2822 C  C   . THR B 1 100 ? 22.78204  1.54866   -23.88843 1.000 29.35151 ? 98  THR B C   1 
ATOM   2823 O  O   . THR B 1 100 ? 22.90636  2.66284   -24.38097 1.000 29.98318 ? 98  THR B O   1 
ATOM   2824 C  CB  . THR B 1 100 ? 24.75337  0.07660   -24.27717 1.000 29.72204 ? 98  THR B CB  1 
ATOM   2825 O  OG1 . THR B 1 100 ? 23.89936  -0.89853  -24.90348 1.000 31.20930 ? 98  THR B OG1 1 
ATOM   2826 C  CG2 . THR B 1 100 ? 26.01352  -0.56047  -23.67729 1.000 30.65660 ? 98  THR B CG2 1 
ATOM   2827 N  N   . VAL B 1 101 ? 21.62829  0.87983   -23.94289 1.000 32.41835 ? 99  VAL B N   1 
ATOM   2828 C  CA  . VAL B 1 101 ? 20.45238  1.50344   -24.54720 1.000 31.38338 ? 99  VAL B CA  1 
ATOM   2829 C  C   . VAL B 1 101 ? 20.04469  2.71944   -23.73296 1.000 33.03616 ? 99  VAL B C   1 
ATOM   2830 O  O   . VAL B 1 101 ? 19.76420  3.79658   -24.27260 1.000 32.96199 ? 99  VAL B O   1 
ATOM   2831 C  CB  . VAL B 1 101 ? 19.30347  0.47795   -24.65942 1.000 31.47626 ? 99  VAL B CB  1 
ATOM   2832 C  CG1 . VAL B 1 101 ? 18.02991  1.17174   -25.08023 1.000 31.28792 ? 99  VAL B CG1 1 
ATOM   2833 C  CG2 . VAL B 1 101 ? 19.66287  -0.58198  -25.67634 1.000 32.53086 ? 99  VAL B CG2 1 
ATOM   2834 N  N   . GLN B 1 102 ? 20.01870  2.55821   -22.40932 1.000 27.39552 ? 100 GLN B N   1 
ATOM   2835 C  CA  . GLN B 1 102 ? 19.68467  3.66341   -21.52742 1.000 34.92299 ? 100 GLN B CA  1 
ATOM   2836 C  C   . GLN B 1 102 ? 20.66656  4.81474   -21.71792 1.000 33.34345 ? 100 GLN B C   1 
ATOM   2837 O  O   . GLN B 1 102 ? 20.27307  5.98487   -21.72305 1.000 31.54985 ? 100 GLN B O   1 
ATOM   2838 C  CB  . GLN B 1 102 ? 19.71475  3.13502   -20.09050 1.000 37.41216 ? 100 GLN B CB  1 
ATOM   2839 C  CG  . GLN B 1 102 ? 18.62690  3.58505   -19.18855 1.000 43.59401 ? 100 GLN B CG  1 
ATOM   2840 C  CD  . GLN B 1 102 ? 18.82217  3.04069   -17.78744 1.000 43.37930 ? 100 GLN B CD  1 
ATOM   2841 O  OE1 . GLN B 1 102 ? 18.46933  3.70222   -16.79885 1.000 36.97139 ? 100 GLN B OE1 1 
ATOM   2842 N  NE2 . GLN B 1 102 ? 19.49314  1.87618   -17.68955 1.000 35.66810 ? 100 GLN B NE2 1 
ATOM   2843 N  N   . ALA B 1 103 ? 21.95057  4.49565   -21.92947 1.000 30.44790 ? 101 ALA B N   1 
ATOM   2844 C  CA  . ALA B 1 103 ? 22.99040  5.52299   -21.96774 1.000 31.16590 ? 101 ALA B CA  1 
ATOM   2845 C  C   . ALA B 1 103 ? 22.89617  6.37986   -23.22980 1.000 29.82699 ? 101 ALA B C   1 
ATOM   2846 O  O   . ALA B 1 103 ? 23.05857  7.60493   -23.16941 1.000 30.89255 ? 101 ALA B O   1 
ATOM   2847 C  CB  . ALA B 1 103 ? 24.37613  4.86800   -21.87360 1.000 29.45899 ? 101 ALA B CB  1 
ATOM   2848 N  N   . VAL B 1 104 ? 22.60666  5.76603   -24.37542 1.000 27.75234 ? 102 VAL B N   1 
ATOM   2849 C  CA  . VAL B 1 104 ? 22.49367  6.55811   -25.59381 1.000 28.52885 ? 102 VAL B CA  1 
ATOM   2850 C  C   . VAL B 1 104 ? 21.17890  7.33560   -25.59881 1.000 30.97748 ? 102 VAL B C   1 
ATOM   2851 O  O   . VAL B 1 104 ? 21.10688  8.45351   -26.13514 1.000 31.23066 ? 102 VAL B O   1 
ATOM   2852 C  CB  . VAL B 1 104 ? 22.64364  5.66361   -26.83965 1.000 29.09244 ? 102 VAL B CB  1 
ATOM   2853 C  CG1 . VAL B 1 104 ? 21.41471  4.81888   -27.03315 1.000 28.23400 ? 102 VAL B CG1 1 
ATOM   2854 C  CG2 . VAL B 1 104 ? 22.90411  6.51961   -28.05634 1.000 29.42611 ? 102 VAL B CG2 1 
ATOM   2855 N  N   . ARG B 1 105 ? 20.13462  6.78320   -24.96950 1.000 31.39037 ? 103 ARG B N   1 
ATOM   2856 C  CA  . ARG B 1 105 ? 18.86391  7.48490   -24.87174 1.000 32.25900 ? 103 ARG B CA  1 
ATOM   2857 C  C   . ARG B 1 105 ? 18.96467  8.68596   -23.94004 1.000 34.29805 ? 103 ARG B C   1 
ATOM   2858 O  O   . ARG B 1 105 ? 18.16929  9.62754   -24.06487 1.000 30.44124 ? 103 ARG B O   1 
ATOM   2859 C  CB  . ARG B 1 105 ? 17.78353  6.50858   -24.41597 1.000 33.68451 ? 103 ARG B CB  1 
ATOM   2860 C  CG  . ARG B 1 105 ? 17.46128  5.44086   -25.44636 1.000 31.72503 ? 103 ARG B CG  1 
ATOM   2861 C  CD  . ARG B 1 105 ? 16.11678  4.75564   -25.12071 1.000 33.34045 ? 103 ARG B CD  1 
ATOM   2862 N  NE  . ARG B 1 105 ? 15.03171  5.73212   -25.21056 1.000 34.44336 ? 103 ARG B NE  1 
ATOM   2863 C  CZ  . ARG B 1 105 ? 13.75318  5.46774   -24.96258 1.000 36.56595 ? 103 ARG B CZ  1 
ATOM   2864 N  NH1 . ARG B 1 105 ? 13.34998  4.25425   -24.62121 1.000 29.91912 ? 103 ARG B NH1 1 
ATOM   2865 N  NH2 . ARG B 1 105 ? 12.85476  6.44542   -25.06869 1.000 35.06933 ? 103 ARG B NH2 1 
ATOM   2866 N  N   . LEU B 1 106 ? 19.96406  8.69590   -23.05070 1.000 32.68660 ? 104 LEU B N   1 
ATOM   2867 C  CA  . LEU B 1 106 ? 20.27850  9.91547   -22.30478 1.000 33.93023 ? 104 LEU B CA  1 
ATOM   2868 C  C   . LEU B 1 106 ? 20.66340  11.05012  -23.23766 1.000 32.95094 ? 104 LEU B C   1 
ATOM   2869 O  O   . LEU B 1 106 ? 20.25193  12.19943  -23.03065 1.000 31.07913 ? 104 LEU B O   1 
ATOM   2870 C  CB  . LEU B 1 106 ? 21.41784  9.65057   -21.33080 1.000 33.83259 ? 104 LEU B CB  1 
ATOM   2871 C  CG  . LEU B 1 106 ? 21.06348  8.97798   -20.01947 1.000 31.01072 ? 104 LEU B CG  1 
ATOM   2872 C  CD1 . LEU B 1 106 ? 22.31367  8.91869   -19.16568 1.000 35.56867 ? 104 LEU B CD1 1 
ATOM   2873 C  CD2 . LEU B 1 106 ? 19.95696  9.73324   -19.30339 1.000 30.64653 ? 104 LEU B CD2 1 
ATOM   2874 N  N   . LEU B 1 107 ? 21.48364  10.75001  -24.26281 1.000 30.07860 ? 105 LEU B N   1 
ATOM   2875 C  CA  . LEU B 1 107 ? 21.82713  11.75128  -25.26591 1.000 30.17768 ? 105 LEU B CA  1 
ATOM   2876 C  C   . LEU B 1 107 ? 20.58857  12.21028  -26.02338 1.000 30.48462 ? 105 LEU B C   1 
ATOM   2877 O  O   . LEU B 1 107 ? 20.33121  13.41459  -26.14959 1.000 31.95286 ? 105 LEU B O   1 
ATOM   2878 C  CB  . LEU B 1 107 ? 22.86886  11.17511  -26.22992 1.000 29.39398 ? 105 LEU B CB  1 
ATOM   2879 C  CG  . LEU B 1 107 ? 24.24923  10.92781  -25.62029 1.000 31.06203 ? 105 LEU B CG  1 
ATOM   2880 C  CD1 . LEU B 1 107 ? 25.25249  10.70719  -26.73588 1.000 29.43813 ? 105 LEU B CD1 1 
ATOM   2881 C  CD2 . LEU B 1 107 ? 24.70176  12.12182  -24.77079 1.000 25.82968 ? 105 LEU B CD2 1 
ATOM   2882 N  N   . THR B 1 108 ? 19.80921  11.25815  -26.54829 1.000 30.82741 ? 106 THR B N   1 
ATOM   2883 C  CA  . THR B 1 108 ? 18.57387  11.61144  -27.25071 1.000 32.81664 ? 106 THR B CA  1 
ATOM   2884 C  C   . THR B 1 108 ? 17.70423  12.53735  -26.42254 1.000 30.24096 ? 106 THR B C   1 
ATOM   2885 O  O   . THR B 1 108 ? 17.15677  13.51058  -26.93694 1.000 29.83170 ? 106 THR B O   1 
ATOM   2886 C  CB  . THR B 1 108 ? 17.74858  10.37214  -27.58041 1.000 33.41783 ? 106 THR B CB  1 
ATOM   2887 O  OG1 . THR B 1 108 ? 18.59440  9.36413   -28.13344 1.000 37.46776 ? 106 THR B OG1 1 
ATOM   2888 C  CG2 . THR B 1 108 ? 16.63786  10.75521  -28.55415 1.000 30.57505 ? 106 THR B CG2 1 
ATOM   2889 N  N   . ASP B 1 109 ? 17.51430  12.19839  -25.14496 1.000 30.49595 ? 107 ASP B N   1 
ATOM   2890 C  CA  . ASP B 1 109 ? 16.57064  12.92617  -24.31606 1.000 31.24327 ? 107 ASP B CA  1 
ATOM   2891 C  C   . ASP B 1 109 ? 17.13789  14.25086  -23.81368 1.000 33.14716 ? 107 ASP B C   1 
ATOM   2892 O  O   . ASP B 1 109 ? 16.36938  15.19222  -23.58245 1.000 29.88040 ? 107 ASP B O   1 
ATOM   2893 C  CB  . ASP B 1 109 ? 16.14172  12.05483  -23.13050 1.000 32.93056 ? 107 ASP B CB  1 
ATOM   2894 C  CG  . ASP B 1 109 ? 15.21826  10.92745  -23.53974 1.000 35.81076 ? 107 ASP B CG  1 
ATOM   2895 O  OD1 . ASP B 1 109 ? 14.77651  10.89654  -24.71787 1.000 34.70892 ? 107 ASP B OD1 1 
ATOM   2896 O  OD2 . ASP B 1 109 ? 14.96239  10.04142  -22.69100 1.000 40.01431 ? 107 ASP B OD2 1 
ATOM   2897 N  N   . HIS B 1 110 ? 18.46418  14.35724  -23.63140 1.000 30.84159 ? 108 HIS B N   1 
ATOM   2898 C  CA  . HIS B 1 110 ? 19.03151  15.52502  -22.94795 1.000 28.42632 ? 108 HIS B CA  1 
ATOM   2899 C  C   . HIS B 1 110 ? 20.20864  16.22014  -23.62945 1.000 30.16855 ? 108 HIS B C   1 
ATOM   2900 O  O   . HIS B 1 110 ? 20.54501  17.33688  -23.21629 1.000 29.38893 ? 108 HIS B O   1 
ATOM   2901 C  CB  . HIS B 1 110 ? 19.47514  15.16226  -21.52835 1.000 28.36712 ? 108 HIS B CB  1 
ATOM   2902 C  CG  . HIS B 1 110 ? 18.39933  14.50754  -20.72378 1.000 33.26606 ? 108 HIS B CG  1 
ATOM   2903 N  ND1 . HIS B 1 110 ? 17.26595  15.17925  -20.32076 1.000 35.04037 ? 108 HIS B ND1 1 
ATOM   2904 C  CD2 . HIS B 1 110 ? 18.25438  13.23274  -20.29462 1.000 32.44228 ? 108 HIS B CD2 1 
ATOM   2905 C  CE1 . HIS B 1 110 ? 16.48072  14.35076  -19.65499 1.000 32.74408 ? 108 HIS B CE1 1 
ATOM   2906 N  NE2 . HIS B 1 110 ? 17.05813  13.16382  -19.62388 1.000 30.30302 ? 108 HIS B NE2 1 
ATOM   2907 N  N   . LEU B 1 111 ? 20.84088  15.63143  -24.63014 1.000 28.54127 ? 109 LEU B N   1 
ATOM   2908 C  CA  . LEU B 1 111 ? 21.94693  16.32561  -25.30308 1.000 32.39330 ? 109 LEU B CA  1 
ATOM   2909 C  C   . LEU B 1 111 ? 21.37058  17.37062  -26.25159 1.000 28.05239 ? 109 LEU B C   1 
ATOM   2910 O  O   . LEU B 1 111 ? 20.61112  17.01133  -27.15327 1.000 28.84503 ? 109 LEU B O   1 
ATOM   2911 C  CB  . LEU B 1 111 ? 22.82831  15.33479  -26.07526 1.000 28.10410 ? 109 LEU B CB  1 
ATOM   2912 C  CG  . LEU B 1 111 ? 24.00784  15.96868  -26.83988 1.000 28.53100 ? 109 LEU B CG  1 
ATOM   2913 C  CD1 . LEU B 1 111 ? 25.01657  16.57859  -25.84274 1.000 29.39413 ? 109 LEU B CD1 1 
ATOM   2914 C  CD2 . LEU B 1 111 ? 24.68077  14.97162  -27.75436 1.000 31.97225 ? 109 LEU B CD2 1 
ATOM   2915 N  N   . PRO B 1 112 ? 21.67901  18.65655  -26.08752 1.000 27.27375 ? 110 PRO B N   1 
ATOM   2916 C  CA  . PRO B 1 112 ? 21.09985  19.64305  -27.00523 1.000 28.19462 ? 110 PRO B CA  1 
ATOM   2917 C  C   . PRO B 1 112 ? 21.79581  19.51583  -28.35429 1.000 28.06012 ? 110 PRO B C   1 
ATOM   2918 O  O   . PRO B 1 112 ? 23.02252  19.40828  -28.42034 1.000 29.16565 ? 110 PRO B O   1 
ATOM   2919 C  CB  . PRO B 1 112 ? 21.38716  20.99230  -26.33079 1.000 27.74827 ? 110 PRO B CB  1 
ATOM   2920 C  CG  . PRO B 1 112 ? 21.92220  20.67144  -24.95823 1.000 29.53514 ? 110 PRO B CG  1 
ATOM   2921 C  CD  . PRO B 1 112 ? 22.56606  19.30323  -25.11184 1.000 29.28111 ? 110 PRO B CD  1 
ATOM   2922 N  N   . GLN B 1 113 ? 21.00571  19.43170  -29.42124 1.000 29.87030 ? 111 GLN B N   1 
ATOM   2923 C  CA  . GLN B 1 113 ? 21.61808  19.34338  -30.74713 1.000 29.24408 ? 111 GLN B CA  1 
ATOM   2924 C  C   . GLN B 1 113 ? 22.53349  20.53995  -30.99238 1.000 28.63344 ? 111 GLN B C   1 
ATOM   2925 O  O   . GLN B 1 113 ? 23.61137  20.40951  -31.58541 1.000 30.26447 ? 111 GLN B O   1 
ATOM   2926 C  CB  . GLN B 1 113 ? 20.55249  19.28020  -31.83611 1.000 28.62971 ? 111 GLN B CB  1 
ATOM   2927 C  CG  . GLN B 1 113 ? 21.17852  19.32346  -33.25844 1.000 29.84683 ? 111 GLN B CG  1 
ATOM   2928 C  CD  . GLN B 1 113 ? 20.17188  19.57606  -34.37092 1.000 31.71568 ? 111 GLN B CD  1 
ATOM   2929 O  OE1 . GLN B 1 113 ? 19.15344  20.24934  -34.17150 1.000 28.48145 ? 111 GLN B OE1 1 
ATOM   2930 N  NE2 . GLN B 1 113 ? 20.46015  19.03988  -35.56303 1.000 28.53587 ? 111 GLN B NE2 1 
ATOM   2931 N  N   . HIS B 1 114 ? 22.13219  21.72253  -30.54244 1.000 30.31876 ? 112 HIS B N   1 
ATOM   2932 C  CA  . HIS B 1 114 ? 22.97818  22.88491  -30.81487 1.000 27.30515 ? 112 HIS B CA  1 
ATOM   2933 C  C   . HIS B 1 114 ? 24.32710  22.76000  -30.10641 1.000 31.71417 ? 112 HIS B C   1 
ATOM   2934 O  O   . HIS B 1 114 ? 25.35806  23.11603  -30.67822 1.000 29.05345 ? 112 HIS B O   1 
ATOM   2935 C  CB  . HIS B 1 114 ? 22.25225  24.15988  -30.42072 1.000 28.89843 ? 112 HIS B CB  1 
ATOM   2936 C  CG  . HIS B 1 114 ? 22.94791  25.39886  -30.86651 1.000 31.32636 ? 112 HIS B CG  1 
ATOM   2937 N  ND1 . HIS B 1 114 ? 24.00481  25.94402  -30.16695 1.000 31.24263 ? 112 HIS B ND1 1 
ATOM   2938 C  CD2 . HIS B 1 114 ? 22.76216  26.18410  -31.95685 1.000 30.79226 ? 112 HIS B CD2 1 
ATOM   2939 C  CE1 . HIS B 1 114 ? 24.41137  27.04031  -30.78685 1.000 34.69028 ? 112 HIS B CE1 1 
ATOM   2940 N  NE2 . HIS B 1 114 ? 23.65812  27.22003  -31.85954 1.000 33.18078 ? 112 HIS B NE2 1 
ATOM   2941 N  N   . SER B 1 115 ? 24.35197  22.22364  -28.86986 1.000 28.95255 ? 113 SER B N   1 
ATOM   2942 C  CA  . SER B 1 115 ? 25.64636  21.96301  -28.22651 1.000 28.46187 ? 113 SER B CA  1 
ATOM   2943 C  C   . SER B 1 115 ? 26.43936  20.90076  -28.98304 1.000 32.88602 ? 113 SER B C   1 
ATOM   2944 O  O   . SER B 1 115 ? 27.67367  20.95037  -29.04473 1.000 33.29872 ? 113 SER B O   1 
ATOM   2945 C  CB  . SER B 1 115 ? 25.46518  21.47245  -26.78518 1.000 29.12343 ? 113 SER B CB  1 
ATOM   2946 O  OG  . SER B 1 115 ? 24.53365  22.20912  -26.05330 1.000 27.37316 ? 113 SER B OG  1 
ATOM   2947 N  N   . LEU B 1 116 ? 25.75894  19.86176  -29.45185 1.000 29.78404 ? 114 LEU B N   1 
ATOM   2948 C  CA  . LEU B 1 116 ? 26.45051  18.82568  -30.19722 1.000 34.07992 ? 114 LEU B CA  1 
ATOM   2949 C  C   . LEU B 1 116 ? 27.10140  19.41036  -31.45123 1.000 33.78162 ? 114 LEU B C   1 
ATOM   2950 O  O   . LEU B 1 116 ? 28.27645  19.15166  -31.73151 1.000 34.64230 ? 114 LEU B O   1 
ATOM   2951 C  CB  . LEU B 1 116 ? 25.47061  17.69897  -30.53133 1.000 28.62803 ? 114 LEU B CB  1 
ATOM   2952 C  CG  . LEU B 1 116 ? 25.92341  16.50974  -31.37895 1.000 31.30137 ? 114 LEU B CG  1 
ATOM   2953 C  CD1 . LEU B 1 116 ? 25.91883  16.88215  -32.89448 1.000 30.83045 ? 114 LEU B CD1 1 
ATOM   2954 C  CD2 . LEU B 1 116 ? 27.27200  15.95139  -30.92426 1.000 28.52092 ? 114 LEU B CD2 1 
ATOM   2955 N  N   . LEU B 1 117 ? 26.35344  20.20704  -32.21622 1.000 31.41833 ? 115 LEU B N   1 
ATOM   2956 C  CA  . LEU B 1 117 ? 26.90439  20.75307  -33.45936 1.000 31.75209 ? 115 LEU B CA  1 
ATOM   2957 C  C   . LEU B 1 117 ? 28.11112  21.64644  -33.18465 1.000 34.47152 ? 115 LEU B C   1 
ATOM   2958 O  O   . LEU B 1 117 ? 29.11441  21.58871  -33.91136 1.000 31.88413 ? 115 LEU B O   1 
ATOM   2959 C  CB  . LEU B 1 117 ? 25.82029  21.52359  -34.22511 1.000 30.37725 ? 115 LEU B CB  1 
ATOM   2960 C  CG  . LEU B 1 117 ? 24.70386  20.59944  -34.76516 1.000 30.57161 ? 115 LEU B CG  1 
ATOM   2961 C  CD1 . LEU B 1 117 ? 23.60512  21.46083  -35.38329 1.000 27.31687 ? 115 LEU B CD1 1 
ATOM   2962 C  CD2 . LEU B 1 117 ? 25.27744  19.62463  -35.80096 1.000 28.77218 ? 115 LEU B CD2 1 
ATOM   2963 N  N   . MET B 1 118 ? 28.04605  22.45155  -32.11615 1.000 30.53886 ? 116 MET B N   1 
ATOM   2964 C  CA  . MET B 1 118 ? 29.16043  23.33106  -31.77994 1.000 32.66520 ? 116 MET B CA  1 
ATOM   2965 C  C   . MET B 1 118 ? 30.39359  22.50795  -31.44450 1.000 32.46295 ? 116 MET B C   1 
ATOM   2966 O  O   . MET B 1 118 ? 31.49984  22.76955  -31.92867 1.000 35.73089 ? 116 MET B O   1 
ATOM   2967 C  CB  . MET B 1 118 ? 28.77729  24.23617  -30.58665 1.000 36.13018 ? 116 MET B CB  1 
ATOM   2968 C  CG  . MET B 1 118 ? 27.64028  25.23309  -30.89945 1.000 30.46054 ? 116 MET B CG  1 
ATOM   2969 S  SD  . MET B 1 118 ? 28.08118  26.32914  -32.27641 1.000 39.64725 ? 116 MET B SD  1 
ATOM   2970 C  CE  . MET B 1 118 ? 26.91044  25.82325  -33.53135 1.000 36.31756 ? 116 MET B CE  1 
ATOM   2971 N  N   . MET B 1 119 ? 30.19557  21.47031  -30.63588 1.000 35.35879 ? 117 MET B N   1 
ATOM   2972 C  CA  . MET B 1 119 ? 31.27306  20.59670  -30.17828 1.000 35.98702 ? 117 MET B CA  1 
ATOM   2973 C  C   . MET B 1 119 ? 31.89740  19.87414  -31.36963 1.000 35.53670 ? 117 MET B C   1 
ATOM   2974 O  O   . MET B 1 119 ? 33.12525  19.82830  -31.52334 1.000 34.37852 ? 117 MET B O   1 
ATOM   2975 C  CB  . MET B 1 119 ? 30.62111  19.64240  -29.17953 1.000 34.37008 ? 117 MET B CB  1 
ATOM   2976 C  CG  . MET B 1 119 ? 30.76690  20.15230  -27.73986 1.000 36.74548 ? 117 MET B CG  1 
ATOM   2977 S  SD  . MET B 1 119 ? 30.55981  18.97156  -26.41148 1.000 39.47851 ? 117 MET B SD  1 
ATOM   2978 C  CE  . MET B 1 119 ? 28.87095  18.48099  -26.75490 1.000 36.25803 ? 117 MET B CE  1 
ATOM   2979 N  N   . ARG B 1 120 ? 31.04232  19.39643  -32.27521 1.000 34.70759 ? 118 ARG B N   1 
ATOM   2980 C  CA  . ARG B 1 120 ? 31.44087  18.59383  -33.42884 1.000 36.50866 ? 118 ARG B CA  1 
ATOM   2981 C  C   . ARG B 1 120 ? 32.20743  19.41211  -34.46743 1.000 36.14419 ? 118 ARG B C   1 
ATOM   2982 O  O   . ARG B 1 120 ? 33.12358  18.89405  -35.11949 1.000 35.78296 ? 118 ARG B O   1 
ATOM   2983 C  CB  . ARG B 1 120 ? 30.18019  17.98302  -34.04019 1.000 31.60759 ? 118 ARG B CB  1 
ATOM   2984 C  CG  . ARG B 1 120 ? 30.36548  17.12494  -35.24408 1.000 36.14627 ? 118 ARG B CG  1 
ATOM   2985 C  CD  . ARG B 1 120 ? 28.99409  16.70204  -35.76559 1.000 33.65031 ? 118 ARG B CD  1 
ATOM   2986 N  NE  . ARG B 1 120 ? 29.05650  15.58166  -36.68448 1.000 34.64310 ? 118 ARG B NE  1 
ATOM   2987 C  CZ  . ARG B 1 120 ? 29.08925  15.69511  -38.00541 1.000 35.68288 ? 118 ARG B CZ  1 
ATOM   2988 N  NH1 . ARG B 1 120 ? 29.08732  16.88029  -38.59966 1.000 34.43784 ? 118 ARG B NH1 1 
ATOM   2989 N  NH2 . ARG B 1 120 ? 29.12513  14.59210  -38.74812 1.000 34.67985 ? 118 ARG B NH2 1 
ATOM   2990 N  N   . ASN B 1 121 ? 31.84918  20.68776  -34.63704 1.000 37.66610 ? 119 ASN B N   1 
ATOM   2991 C  CA  . ASN B 1 121 ? 32.58786  21.54801  -35.54933 1.000 39.21247 ? 119 ASN B CA  1 
ATOM   2992 C  C   . ASN B 1 121 ? 34.06461  21.62713  -35.17803 1.000 40.58212 ? 119 ASN B C   1 
ATOM   2993 O  O   . ASN B 1 121 ? 34.87596  22.03871  -36.00800 1.000 42.72105 ? 119 ASN B O   1 
ATOM   2994 C  CB  . ASN B 1 121 ? 31.94672  22.95492  -35.58177 1.000 35.80522 ? 119 ASN B CB  1 
ATOM   2995 C  CG  . ASN B 1 121 ? 30.68709  22.99607  -36.43158 1.000 33.78343 ? 119 ASN B CG  1 
ATOM   2996 O  OD1 . ASN B 1 121 ? 30.43066  22.07346  -37.17830 1.000 34.69403 ? 119 ASN B OD1 1 
ATOM   2997 N  ND2 . ASN B 1 121 ? 29.89265  24.06181  -36.31177 1.000 32.48621 ? 119 ASN B ND2 1 
ATOM   2998 N  N   . ALA B 1 122 ? 34.43237  21.22067  -33.96452 1.000 39.51058 ? 120 ALA B N   1 
ATOM   2999 C  CA  . ALA B 1 122 ? 35.80715  21.29476  -33.49349 1.000 37.99636 ? 120 ALA B CA  1 
ATOM   3000 C  C   . ALA B 1 122 ? 36.43737  19.93919  -33.19978 1.000 40.98304 ? 120 ALA B C   1 
ATOM   3001 O  O   . ALA B 1 122 ? 37.59497  19.89947  -32.76313 1.000 42.13449 ? 120 ALA B O   1 
ATOM   3002 C  CB  . ALA B 1 122 ? 35.87474  22.16180  -32.22947 1.000 39.73868 ? 120 ALA B CB  1 
ATOM   3003 N  N   . LEU B 1 123 ? 35.71075  18.83514  -33.39051 1.000 36.70869 ? 121 LEU B N   1 
ATOM   3004 C  CA  . LEU B 1 123 ? 36.25683  17.51226  -33.13194 1.000 38.64748 ? 121 LEU B CA  1 
ATOM   3005 C  C   . LEU B 1 123 ? 37.24499  17.11586  -34.22864 1.000 37.02107 ? 121 LEU B C   1 
ATOM   3006 O  O   . LEU B 1 123 ? 37.20375  17.65073  -35.33128 1.000 37.26385 ? 121 LEU B O   1 
ATOM   3007 C  CB  . LEU B 1 123 ? 35.13008  16.47704  -33.05412 1.000 35.58168 ? 121 LEU B CB  1 
ATOM   3008 C  CG  . LEU B 1 123 ? 34.33460  16.42343  -31.73885 1.000 36.79473 ? 121 LEU B CG  1 
ATOM   3009 C  CD1 . LEU B 1 123 ? 33.10068  15.56900  -31.89954 1.000 34.47210 ? 121 LEU B CD1 1 
ATOM   3010 C  CD2 . LEU B 1 123 ? 35.16663  15.92185  -30.57143 1.000 39.31528 ? 121 LEU B CD2 1 
ATOM   3011 N  N   . PRO B 1 124 ? 38.12561  16.15635  -33.95297 1.000 39.34221 ? 122 PRO B N   1 
ATOM   3012 C  CA  . PRO B 1 124 ? 38.98880  15.61133  -35.01168 1.000 41.70945 ? 122 PRO B CA  1 
ATOM   3013 C  C   . PRO B 1 124 ? 38.20467  14.96954  -36.15507 1.000 41.91711 ? 122 PRO B C   1 
ATOM   3014 O  O   . PRO B 1 124 ? 37.06286  14.51502  -36.00619 1.000 40.63789 ? 122 PRO B O   1 
ATOM   3015 C  CB  . PRO B 1 124 ? 39.82379  14.55536  -34.28210 1.000 40.91094 ? 122 PRO B CB  1 
ATOM   3016 C  CG  . PRO B 1 124 ? 39.72551  14.88420  -32.84229 1.000 41.63743 ? 122 PRO B CG  1 
ATOM   3017 C  CD  . PRO B 1 124 ? 38.40699  15.55618  -32.63683 1.000 41.52250 ? 122 PRO B CD  1 
ATOM   3018 N  N   . GLU B 1 125 ? 38.90592  14.84098  -37.28316 1.000 42.10140 ? 123 GLU B N   1 
ATOM   3019 C  CA  . GLU B 1 125 ? 38.31141  14.41586  -38.55485 1.000 48.25232 ? 123 GLU B CA  1 
ATOM   3020 C  C   . GLU B 1 125 ? 37.71843  12.99992  -38.52112 1.000 44.94034 ? 123 GLU B C   1 
ATOM   3021 O  O   . GLU B 1 125 ? 36.59607  12.78253  -38.97459 1.000 47.97953 ? 123 GLU B O   1 
ATOM   3022 C  CB  . GLU B 1 125 ? 39.36018  14.50630  -39.66286 1.000 47.41219 ? 123 GLU B CB  1 
ATOM   3023 C  CG  . GLU B 1 125 ? 38.88129  13.94506  -40.98654 1.000 52.35797 ? 123 GLU B CG  1 
ATOM   3024 C  CD  . GLU B 1 125 ? 39.83163  14.27009  -42.12050 1.000 58.09784 ? 123 GLU B CD  1 
ATOM   3025 O  OE1 . GLU B 1 125 ? 41.05756  14.10141  -41.92818 1.000 60.53383 ? 123 GLU B OE1 1 
ATOM   3026 O  OE2 . GLU B 1 125 ? 39.35247  14.72050  -43.18466 1.000 58.93538 ? 123 GLU B OE2 1 
ATOM   3027 N  N   . ASP B 1 126 ? 38.45257  12.00157  -38.08278 1.000 37.89667 ? 124 ASP B N   1 
ATOM   3028 C  CA  . ASP B 1 126 ? 37.77787  10.70960  -38.29359 1.000 47.32501 ? 124 ASP B CA  1 
ATOM   3029 C  C   . ASP B 1 126 ? 37.41470  10.08243  -36.96308 1.000 42.83753 ? 124 ASP B C   1 
ATOM   3030 O  O   . ASP B 1 126 ? 37.77797  8.93441   -36.68402 1.000 41.34674 ? 124 ASP B O   1 
ATOM   3031 C  CB  . ASP B 1 126 ? 38.61543  9.74671   -39.15475 1.000 45.12237 ? 124 ASP B CB  1 
ATOM   3032 C  CG  . ASP B 1 126 ? 37.84881  8.43984   -39.54431 1.000 51.04699 ? 124 ASP B CG  1 
ATOM   3033 O  OD1 . ASP B 1 126 ? 36.59543  8.43395   -39.66452 1.000 49.92518 ? 124 ASP B OD1 1 
ATOM   3034 O  OD2 . ASP B 1 126 ? 38.52343  7.40287   -39.75546 1.000 50.59726 ? 124 ASP B OD2 1 
ATOM   3035 N  N   . ALA B 1 127 ? 36.69332  10.84544  -36.13970 1.000 40.61395 ? 125 ALA B N   1 
ATOM   3036 C  CA  . ALA B 1 127 ? 36.32951  10.40917  -34.79574 1.000 36.22679 ? 125 ALA B CA  1 
ATOM   3037 C  C   . ALA B 1 127 ? 34.95001  9.77034   -34.89306 1.000 40.65003 ? 125 ALA B C   1 
ATOM   3038 O  O   . ALA B 1 127 ? 33.92545  10.46411  -34.88392 1.000 36.81654 ? 125 ALA B O   1 
ATOM   3039 C  CB  . ALA B 1 127 ? 36.37553  11.58161  -33.82084 1.000 35.27563 ? 125 ALA B CB  1 
ATOM   3040 N  N   . THR B 1 128 ? 34.93318  8.43837   -34.99265 1.000 36.42516 ? 126 THR B N   1 
ATOM   3041 C  CA  . THR B 1 128 ? 33.74772  7.64574   -35.29008 1.000 37.05931 ? 126 THR B CA  1 
ATOM   3042 C  C   . THR B 1 128 ? 33.69532  6.44576   -34.35070 1.000 38.43324 ? 126 THR B C   1 
ATOM   3043 O  O   . THR B 1 128 ? 34.72704  5.85843   -34.00088 1.000 35.08721 ? 126 THR B O   1 
ATOM   3044 C  CB  . THR B 1 128 ? 33.77535  7.14914   -36.76062 1.000 42.98617 ? 126 THR B CB  1 
ATOM   3045 O  OG1 . THR B 1 128 ? 32.79873  6.13910   -36.96325 1.000 36.76943 ? 126 THR B OG1 1 
ATOM   3046 C  CG2 . THR B 1 128 ? 35.16376  6.51961   -37.15307 1.000 41.03186 ? 126 THR B CG2 1 
ATOM   3047 N  N   . GLY B 1 129 ? 32.47906  6.06060   -33.96563 1.000 34.69750 ? 127 GLY B N   1 
ATOM   3048 C  CA  . GLY B 1 129 ? 32.29777  4.83575   -33.19590 1.000 33.24485 ? 127 GLY B CA  1 
ATOM   3049 C  C   . GLY B 1 129 ? 32.53364  3.56345   -33.97706 1.000 34.40603 ? 127 GLY B C   1 
ATOM   3050 O  O   . GLY B 1 129 ? 32.52502  2.48811   -33.37954 1.000 33.98512 ? 127 GLY B O   1 
ATOM   3051 N  N   . LEU B 1 130 ? 32.76152  3.65769   -35.29105 1.000 35.84404 ? 128 LEU B N   1 
ATOM   3052 C  CA  . LEU B 1 130 ? 33.33536  2.53339   -36.00899 1.000 34.05029 ? 128 LEU B CA  1 
ATOM   3053 C  C   . LEU B 1 130 ? 34.63654  2.07046   -35.36463 1.000 36.78838 ? 128 LEU B C   1 
ATOM   3054 O  O   . LEU B 1 130 ? 34.99742  0.89465   -35.49813 1.000 34.59635 ? 128 LEU B O   1 
ATOM   3055 C  CB  . LEU B 1 130 ? 33.57895  2.90692   -37.47863 1.000 38.61475 ? 128 LEU B CB  1 
ATOM   3056 C  CG  . LEU B 1 130 ? 32.32816  3.12031   -38.33869 1.000 38.06969 ? 128 LEU B CG  1 
ATOM   3057 C  CD1 . LEU B 1 130 ? 32.73540  3.66642   -39.69896 1.000 43.06454 ? 128 LEU B CD1 1 
ATOM   3058 C  CD2 . LEU B 1 130 ? 31.52800  1.83125   -38.50720 1.000 37.86855 ? 128 LEU B CD2 1 
ATOM   3059 N  N   . ASP B 1 131 ? 35.31896  2.94555   -34.62041 1.000 31.71198 ? 129 ASP B N   1 
ATOM   3060 C  CA  . ASP B 1 131 ? 36.52350  2.58077   -33.89056 1.000 33.86951 ? 129 ASP B CA  1 
ATOM   3061 C  C   . ASP B 1 131 ? 36.26028  2.22317   -32.43621 1.000 34.29797 ? 129 ASP B C   1 
ATOM   3062 O  O   . ASP B 1 131 ? 37.22037  2.03003   -31.68214 1.000 35.40955 ? 129 ASP B O   1 
ATOM   3063 C  CB  . ASP B 1 131 ? 37.54419  3.71637   -33.94522 1.000 35.84169 ? 129 ASP B CB  1 
ATOM   3064 C  CG  . ASP B 1 131 ? 38.08288  3.94496   -35.33161 1.000 37.13995 ? 129 ASP B CG  1 
ATOM   3065 O  OD1 . ASP B 1 131 ? 38.54005  2.97890   -35.94524 1.000 41.05116 ? 129 ASP B OD1 1 
ATOM   3066 O  OD2 . ASP B 1 131 ? 38.01902  5.08987   -35.81160 1.000 39.22835 ? 129 ASP B OD2 1 
ATOM   3067 N  N   . SER B 1 132 ? 34.99873  2.16746   -32.00639 1.000 34.21522 ? 130 SER B N   1 
ATOM   3068 C  CA  . SER B 1 132 ? 34.68591  1.71581   -30.64182 1.000 33.86395 ? 130 SER B CA  1 
ATOM   3069 C  C   . SER B 1 132 ? 35.24120  0.32153   -30.36523 1.000 35.54174 ? 130 SER B C   1 
ATOM   3070 O  O   . SER B 1 132 ? 34.88627  -0.62548  -31.07923 1.000 34.02305 ? 130 SER B O   1 
ATOM   3071 C  CB  . SER B 1 132 ? 33.17221  1.68539   -30.39316 1.000 32.33967 ? 130 SER B CB  1 
ATOM   3072 O  OG  . SER B 1 132 ? 32.86936  0.95111   -29.21061 1.000 32.93529 ? 130 SER B OG  1 
ATOM   3073 N  N   . PRO B 1 133 ? 36.05718  0.13437   -29.32446 1.000 36.17684 ? 131 PRO B N   1 
ATOM   3074 C  CA  . PRO B 1 133 ? 36.53781  -1.23186  -29.02204 1.000 37.75092 ? 131 PRO B CA  1 
ATOM   3075 C  C   . PRO B 1 133 ? 35.43271  -2.13216  -28.50505 1.000 37.60067 ? 131 PRO B C   1 
ATOM   3076 O  O   . PRO B 1 133 ? 35.44054  -3.34204  -28.77607 1.000 37.50722 ? 131 PRO B O   1 
ATOM   3077 C  CB  . PRO B 1 133 ? 37.62125  -1.01987  -27.95225 1.000 40.04658 ? 131 PRO B CB  1 
ATOM   3078 C  CG  . PRO B 1 133 ? 37.84779  0.44821   -27.86580 1.000 41.75817 ? 131 PRO B CG  1 
ATOM   3079 C  CD  . PRO B 1 133 ? 36.64162  1.15592   -28.44439 1.000 36.29080 ? 131 PRO B CD  1 
ATOM   3080 N  N   . GLY B 1 134 ? 34.47551  -1.58544  -27.74972 1.000 35.90401 ? 132 GLY B N   1 
ATOM   3081 C  CA  . GLY B 1 134 ? 33.33708  -2.40037  -27.34761 1.000 35.70839 ? 132 GLY B CA  1 
ATOM   3082 C  C   . GLY B 1 134 ? 32.57770  -2.93207  -28.54776 1.000 34.68439 ? 132 GLY B C   1 
ATOM   3083 O  O   . GLY B 1 134 ? 32.24033  -4.11100  -28.62404 1.000 33.46733 ? 132 GLY B O   1 
ATOM   3084 N  N   . TYR B 1 135 ? 32.30829  -2.06298  -29.50846 1.000 34.04664 ? 133 TYR B N   1 
ATOM   3085 C  CA  . TYR B 1 135 ? 31.55464  -2.46486  -30.68580 1.000 35.59039 ? 133 TYR B CA  1 
ATOM   3086 C  C   . TYR B 1 135 ? 32.35019  -3.41929  -31.57163 1.000 36.40076 ? 133 TYR B C   1 
ATOM   3087 O  O   . TYR B 1 135 ? 31.83192  -4.45224  -32.01475 1.000 35.20334 ? 133 TYR B O   1 
ATOM   3088 C  CB  . TYR B 1 135 ? 31.15672  -1.23111  -31.47921 1.000 34.08034 ? 133 TYR B CB  1 
ATOM   3089 C  CG  . TYR B 1 135 ? 30.03470  -1.53273  -32.40603 1.000 42.26667 ? 133 TYR B CG  1 
ATOM   3090 C  CD1 . TYR B 1 135 ? 28.74726  -1.78396  -31.92163 1.000 44.23504 ? 133 TYR B CD1 1 
ATOM   3091 C  CD2 . TYR B 1 135 ? 30.27501  -1.66846  -33.76385 1.000 40.19531 ? 133 TYR B CD2 1 
ATOM   3092 C  CE1 . TYR B 1 135 ? 27.71975  -2.08048  -32.79411 1.000 49.05274 ? 133 TYR B CE1 1 
ATOM   3093 C  CE2 . TYR B 1 135 ? 29.27569  -1.98156  -34.62591 1.000 44.24267 ? 133 TYR B CE2 1 
ATOM   3094 C  CZ  . TYR B 1 135 ? 28.00552  -2.17853  -34.15312 1.000 52.21966 ? 133 TYR B CZ  1 
ATOM   3095 O  OH  . TYR B 1 135 ? 27.02076  -2.48086  -35.05938 1.000 59.59959 ? 133 TYR B OH  1 
ATOM   3096 N  N   . ARG B 1 136 ? 33.60621  -3.08010  -31.85956 1.000 34.97726 ? 134 ARG B N   1 
ATOM   3097 C  CA  . ARG B 1 136 ? 34.42578  -3.93750  -32.71847 1.000 36.33399 ? 134 ARG B CA  1 
ATOM   3098 C  C   . ARG B 1 136 ? 34.62580  -5.32129  -32.11234 1.000 35.27273 ? 134 ARG B C   1 
ATOM   3099 O  O   . ARG B 1 136 ? 34.60575  -6.33740  -32.82932 1.000 35.97471 ? 134 ARG B O   1 
ATOM   3100 C  CB  . ARG B 1 136 ? 35.78222  -3.28164  -32.96355 1.000 36.80123 ? 134 ARG B CB  1 
ATOM   3101 C  CG  . ARG B 1 136 ? 35.73516  -1.98730  -33.75035 1.000 39.09158 ? 134 ARG B CG  1 
ATOM   3102 C  CD  . ARG B 1 136 ? 37.07700  -1.28398  -33.66724 1.000 37.41765 ? 134 ARG B CD  1 
ATOM   3103 N  NE  . ARG B 1 136 ? 38.07177  -1.94127  -34.50517 1.000 49.76685 ? 134 ARG B NE  1 
ATOM   3104 C  CZ  . ARG B 1 136 ? 38.19152  -1.72404  -35.80731 1.000 50.68712 ? 134 ARG B CZ  1 
ATOM   3105 N  NH1 . ARG B 1 136 ? 37.41301  -0.85428  -36.43215 1.000 50.18762 ? 134 ARG B NH1 1 
ATOM   3106 N  NH2 . ARG B 1 136 ? 39.10674  -2.39756  -36.49841 1.000 45.72866 ? 134 ARG B NH2 1 
ATOM   3107 N  N   . ASN B 1 137 ? 34.85370  -5.38793  -30.80439 1.000 30.77381 ? 135 ASN B N   1 
ATOM   3108 C  CA  . ASN B 1 137 ? 35.08442  -6.68989  -30.18886 1.000 33.08047 ? 135 ASN B CA  1 
ATOM   3109 C  C   . ASN B 1 137 ? 33.79498  -7.46718  -29.99261 1.000 35.47875 ? 135 ASN B C   1 
ATOM   3110 O  O   . ASN B 1 137 ? 33.81905  -8.70414  -29.99180 1.000 33.92744 ? 135 ASN B O   1 
ATOM   3111 C  CB  . ASN B 1 137 ? 35.81362  -6.52803  -28.86006 1.000 33.48671 ? 135 ASN B CB  1 
ATOM   3112 C  CG  . ASN B 1 137 ? 37.25787  -6.06371  -29.05211 1.000 39.09581 ? 135 ASN B CG  1 
ATOM   3113 O  OD1 . ASN B 1 137 ? 38.00266  -6.64527  -29.83934 1.000 38.88140 ? 135 ASN B OD1 1 
ATOM   3114 N  ND2 . ASN B 1 137 ? 37.64158  -4.99198  -28.36091 1.000 39.62688 ? 135 ASN B ND2 1 
ATOM   3115 N  N   . LEU B 1 138 ? 32.66796  -6.77725  -29.82382 1.000 36.25393 ? 136 LEU B N   1 
ATOM   3116 C  CA  . LEU B 1 138 ? 31.39466  -7.48955  -29.76465 1.000 35.47801 ? 136 LEU B CA  1 
ATOM   3117 C  C   . LEU B 1 138 ? 31.07411  -8.12983  -31.11220 1.000 35.04393 ? 136 LEU B C   1 
ATOM   3118 O  O   . LEU B 1 138 ? 30.60808  -9.27693  -31.16052 1.000 35.22597 ? 136 LEU B O   1 
ATOM   3119 C  CB  . LEU B 1 138 ? 30.27542  -6.53510  -29.30955 1.000 33.26040 ? 136 LEU B CB  1 
ATOM   3120 C  CG  . LEU B 1 138 ? 28.83731  -7.06553  -29.39225 1.000 35.09519 ? 136 LEU B CG  1 
ATOM   3121 C  CD1 . LEU B 1 138 ? 28.61645  -8.16050  -28.35735 1.000 35.99603 ? 136 LEU B CD1 1 
ATOM   3122 C  CD2 . LEU B 1 138 ? 27.81320  -5.94625  -29.16921 1.000 34.68076 ? 136 LEU B CD2 1 
ATOM   3123 N  N   . ARG B 1 139 ? 31.34352  -7.41430  -32.21572 1.000 34.96932 ? 137 ARG B N   1 
ATOM   3124 C  CA  . ARG B 1 139 ? 31.18876  -7.99319  -33.55407 1.000 38.65812 ? 137 ARG B CA  1 
ATOM   3125 C  C   . ARG B 1 139 ? 32.11215  -9.19376  -33.75047 1.000 39.16084 ? 137 ARG B C   1 
ATOM   3126 O  O   . ARG B 1 139 ? 31.69191  -10.24737 -34.25832 1.000 39.56605 ? 137 ARG B O   1 
ATOM   3127 C  CB  . ARG B 1 139 ? 31.46657  -6.93531  -34.62894 1.000 38.91899 ? 137 ARG B CB  1 
ATOM   3128 C  CG  . ARG B 1 139 ? 30.42423  -5.79514  -34.75894 1.000 45.54664 ? 137 ARG B CG  1 
ATOM   3129 C  CD  . ARG B 1 139 ? 28.99415  -6.33960  -34.98744 1.000 53.96346 ? 137 ARG B CD  1 
ATOM   3130 N  NE  . ARG B 1 139 ? 28.78022  -6.73747  -36.38052 1.000 55.19382 ? 137 ARG B NE  1 
ATOM   3131 C  CZ  . ARG B 1 139 ? 27.94750  -7.69386  -36.77367 1.000 48.84233 ? 137 ARG B CZ  1 
ATOM   3132 N  NH1 . ARG B 1 139 ? 27.18925  -8.35344  -35.90711 1.000 44.09092 ? 137 ARG B NH1 1 
ATOM   3133 N  NH2 . ARG B 1 139 ? 27.87095  -7.99717  -38.07113 1.000 49.10797 ? 137 ARG B NH2 1 
ATOM   3134 N  N   . ARG B 1 140 ? 33.38176  -9.04940  -33.35448 1.000 37.64147 ? 138 ARG B N   1 
ATOM   3135 C  CA  . ARG B 1 140 ? 34.36120  -10.13359 -33.50377 1.000 38.40721 ? 138 ARG B CA  1 
ATOM   3136 C  C   . ARG B 1 140 ? 33.90985  -11.39021 -32.77831 1.000 37.89366 ? 138 ARG B C   1 
ATOM   3137 O  O   . ARG B 1 140 ? 33.91662  -12.48809 -33.35164 1.000 36.24096 ? 138 ARG B O   1 
ATOM   3138 C  CB  . ARG B 1 140 ? 35.72304  -9.67693  -32.97127 1.000 38.26203 ? 138 ARG B CB  1 
ATOM   3139 C  CG  . ARG B 1 140 ? 36.95432  -10.07961 -33.75647 1.000 48.37261 ? 138 ARG B CG  1 
ATOM   3140 C  CD  . ARG B 1 140 ? 38.21533  -10.00159 -32.84514 1.000 49.42232 ? 138 ARG B CD  1 
ATOM   3141 N  NE  . ARG B 1 140 ? 38.48957  -8.65300  -32.32996 1.000 39.87096 ? 138 ARG B NE  1 
ATOM   3142 C  CZ  . ARG B 1 140 ? 38.54323  -7.55026  -33.06440 1.000 48.40464 ? 138 ARG B CZ  1 
ATOM   3143 N  NH1 . ARG B 1 140 ? 38.50727  -7.59805  -34.38896 1.000 53.89527 ? 138 ARG B NH1 1 
ATOM   3144 N  NH2 . ARG B 1 140 ? 38.67493  -6.36464  -32.45732 1.000 43.90914 ? 138 ARG B NH2 1 
ATOM   3145 N  N   . VAL B 1 141 ? 33.51765  -11.24621 -31.50622 1.000 35.23083 ? 139 VAL B N   1 
ATOM   3146 C  CA  . VAL B 1 141 ? 33.26386  -12.39725 -30.65143 1.000 35.96079 ? 139 VAL B CA  1 
ATOM   3147 C  C   . VAL B 1 141 ? 31.94062  -13.07127 -30.97639 1.000 37.46522 ? 139 VAL B C   1 
ATOM   3148 O  O   . VAL B 1 141 ? 31.75444  -14.24883 -30.63264 1.000 33.22810 ? 139 VAL B O   1 
ATOM   3149 C  CB  . VAL B 1 141 ? 33.29804  -11.98499 -29.16985 1.000 33.78355 ? 139 VAL B CB  1 
ATOM   3150 C  CG1 . VAL B 1 141 ? 31.93904  -11.48322 -28.70198 1.000 36.88899 ? 139 VAL B CG1 1 
ATOM   3151 C  CG2 . VAL B 1 141 ? 33.80954  -13.10821 -28.29009 1.000 36.47772 ? 139 VAL B CG2 1 
ATOM   3152 N  N   . ALA B 1 142 ? 31.02864  -12.36770 -31.65380 1.000 36.28542 ? 140 ALA B N   1 
ATOM   3153 C  CA  . ALA B 1 142 ? 29.71855  -12.93895 -31.94695 1.000 36.31818 ? 140 ALA B CA  1 
ATOM   3154 C  C   . ALA B 1 142 ? 29.83241  -14.21392 -32.77108 1.000 36.80035 ? 140 ALA B C   1 
ATOM   3155 O  O   . ALA B 1 142 ? 29.00572  -15.12120 -32.61285 1.000 34.08635 ? 140 ALA B O   1 
ATOM   3156 C  CB  . ALA B 1 142 ? 28.84445  -11.91948 -32.68422 1.000 34.77660 ? 140 ALA B CB  1 
ATOM   3157 N  N   . ARG B 1 143 ? 30.85479  -14.29854 -33.65058 1.000 36.57556 ? 141 ARG B N   1 
ATOM   3158 C  CA  . ARG B 1 143 ? 31.00702  -15.48459 -34.49467 1.000 37.70652 ? 141 ARG B CA  1 
ATOM   3159 C  C   . ARG B 1 143 ? 31.42322  -16.70415 -33.68373 1.000 37.20512 ? 141 ARG B C   1 
ATOM   3160 O  O   . ARG B 1 143 ? 30.71698  -17.72508 -33.73512 1.000 33.16663 ? 141 ARG B O   1 
ATOM   3161 C  CB  . ARG B 1 143 ? 31.97456  -15.18801 -35.64686 1.000 42.13773 ? 141 ARG B CB  1 
ATOM   3162 C  CG  . ARG B 1 143 ? 31.28261  -14.63297 -36.89253 1.000 44.38421 ? 141 ARG B CG  1 
ATOM   3163 C  CD  . ARG B 1 143 ? 30.18919  -15.58595 -37.32265 1.000 47.99484 ? 141 ARG B CD  1 
ATOM   3164 N  NE  . ARG B 1 143 ? 28.89031  -15.26686 -36.73280 1.000 50.99153 ? 141 ARG B NE  1 
ATOM   3165 C  CZ  . ARG B 1 143 ? 27.75712  -15.85208 -37.09486 1.000 47.86733 ? 141 ARG B CZ  1 
ATOM   3166 N  NH1 . ARG B 1 143 ? 27.73862  -16.79770 -38.01814 1.000 48.43028 ? 141 ARG B NH1 1 
ATOM   3167 N  NH2 . ARG B 1 143 ? 26.62462  -15.51014 -36.48995 1.000 44.44343 ? 141 ARG B NH2 1 
ATOM   3168 N  N   . PRO B 1 144 ? 32.52256  -16.67930 -32.91569 1.000 38.83498 ? 142 PRO B N   1 
ATOM   3169 C  CA  . PRO B 1 144 ? 32.80480  -17.82275 -32.02922 1.000 36.77007 ? 142 PRO B CA  1 
ATOM   3170 C  C   . PRO B 1 144 ? 31.65897  -18.12934 -31.07761 1.000 36.77487 ? 142 PRO B C   1 
ATOM   3171 O  O   . PRO B 1 144 ? 31.48326  -19.29498 -30.69258 1.000 35.08860 ? 142 PRO B O   1 
ATOM   3172 C  CB  . PRO B 1 144 ? 34.05565  -17.38305 -31.25643 1.000 39.12031 ? 142 PRO B CB  1 
ATOM   3173 C  CG  . PRO B 1 144 ? 34.63399  -16.26357 -32.04422 1.000 40.71782 ? 142 PRO B CG  1 
ATOM   3174 C  CD  . PRO B 1 144 ? 33.52664  -15.60403 -32.76819 1.000 36.87108 ? 142 PRO B CD  1 
ATOM   3175 N  N   . VAL B 1 145 ? 30.85957  -17.12413 -30.69174 1.000 33.99930 ? 143 VAL B N   1 
ATOM   3176 C  CA  . VAL B 1 145 ? 29.71628  -17.41025 -29.82843 1.000 33.67831 ? 143 VAL B CA  1 
ATOM   3177 C  C   . VAL B 1 145 ? 28.67069  -18.22198 -30.58564 1.000 34.00519 ? 143 VAL B C   1 
ATOM   3178 O  O   . VAL B 1 145 ? 28.18738  -19.24128 -30.09173 1.000 31.95516 ? 143 VAL B O   1 
ATOM   3179 C  CB  . VAL B 1 145 ? 29.10158  -16.12033 -29.25218 1.000 33.52507 ? 143 VAL B CB  1 
ATOM   3180 C  CG1 . VAL B 1 145 ? 27.73096  -16.41561 -28.69776 1.000 33.50618 ? 143 VAL B CG1 1 
ATOM   3181 C  CG2 . VAL B 1 145 ? 29.98533  -15.51992 -28.17705 1.000 34.44953 ? 143 VAL B CG2 1 
ATOM   3182 N  N   . TRP B 1 146 ? 28.27116  -17.76567 -31.77743 1.000 37.53257 ? 144 TRP B N   1 
ATOM   3183 C  CA  . TRP B 1 146 ? 27.29280  -18.54430 -32.52613 1.000 34.37831 ? 144 TRP B CA  1 
ATOM   3184 C  C   . TRP B 1 146 ? 27.80548  -19.95584 -32.78836 1.000 34.57336 ? 144 TRP B C   1 
ATOM   3185 O  O   . TRP B 1 146 ? 27.05872  -20.93174 -32.65451 1.000 35.82835 ? 144 TRP B O   1 
ATOM   3186 C  CB  . TRP B 1 146 ? 26.94605  -17.89677 -33.86408 1.000 36.81850 ? 144 TRP B CB  1 
ATOM   3187 C  CG  . TRP B 1 146 ? 26.06263  -18.86424 -34.56587 1.000 38.66324 ? 144 TRP B CG  1 
ATOM   3188 C  CD1 . TRP B 1 146 ? 26.39183  -19.68044 -35.61076 1.000 40.83200 ? 144 TRP B CD1 1 
ATOM   3189 C  CD2 . TRP B 1 146 ? 24.71854  -19.19561 -34.20184 1.000 37.05171 ? 144 TRP B CD2 1 
ATOM   3190 N  NE1 . TRP B 1 146 ? 25.32181  -20.48939 -35.93091 1.000 39.90411 ? 144 TRP B NE1 1 
ATOM   3191 C  CE2 . TRP B 1 146 ? 24.28419  -20.21286 -35.08246 1.000 41.27042 ? 144 TRP B CE2 1 
ATOM   3192 C  CE3 . TRP B 1 146 ? 23.83911  -18.72457 -33.22370 1.000 37.17100 ? 144 TRP B CE3 1 
ATOM   3193 C  CZ2 . TRP B 1 146 ? 23.00001  -20.75970 -35.02162 1.000 39.43733 ? 144 TRP B CZ2 1 
ATOM   3194 C  CZ3 . TRP B 1 146 ? 22.56151  -19.26516 -33.15766 1.000 38.84453 ? 144 TRP B CZ3 1 
ATOM   3195 C  CH2 . TRP B 1 146 ? 22.15330  -20.27554 -34.05147 1.000 36.64885 ? 144 TRP B CH2 1 
ATOM   3196 N  N   . LYS B 1 147 ? 29.07458  -20.07646 -33.17419 1.000 34.71719 ? 145 LYS B N   1 
ATOM   3197 C  CA  . LYS B 1 147 ? 29.65308  -21.38884 -33.46075 1.000 40.12557 ? 145 LYS B CA  1 
ATOM   3198 C  C   . LYS B 1 147 ? 29.55227  -22.32086 -32.25306 1.000 38.76722 ? 145 LYS B C   1 
ATOM   3199 O  O   . LYS B 1 147 ? 29.13795  -23.47733 -32.38297 1.000 33.73206 ? 145 LYS B O   1 
ATOM   3200 C  CB  . LYS B 1 147 ? 31.11007  -21.23355 -33.89236 1.000 39.50252 ? 145 LYS B CB  1 
ATOM   3201 C  CG  . LYS B 1 147 ? 31.34158  -20.68428 -35.29752 1.000 47.44699 ? 145 LYS B CG  1 
ATOM   3202 C  CD  . LYS B 1 147 ? 30.33522  -21.18809 -36.34194 1.000 51.05214 ? 145 LYS B CD  1 
ATOM   3203 C  CE  . LYS B 1 147 ? 30.29378  -20.19966 -37.51790 1.000 55.02350 ? 145 LYS B CE  1 
ATOM   3204 N  NZ  . LYS B 1 147 ? 29.01809  -20.24206 -38.29270 1.000 59.24068 ? 145 LYS B NZ  1 
ATOM   3205 N  N   . ALA B 1 148 ? 29.91913  -21.83013 -31.06504 1.000 35.97329 ? 146 ALA B N   1 
ATOM   3206 C  CA  . ALA B 1 148 ? 29.79343  -22.64803 -29.85646 1.000 34.50408 ? 146 ALA B CA  1 
ATOM   3207 C  C   . ALA B 1 148 ? 28.36039  -23.14071 -29.65603 1.000 36.06929 ? 146 ALA B C   1 
ATOM   3208 O  O   . ALA B 1 148 ? 28.13629  -24.31378 -29.31202 1.000 34.45242 ? 146 ALA B O   1 
ATOM   3209 C  CB  . ALA B 1 148 ? 30.26013  -21.85111 -28.63656 1.000 35.10935 ? 146 ALA B CB  1 
ATOM   3210 N  N   . TYR B 1 149 ? 27.36798  -22.26905 -29.87118 1.000 31.39667 ? 147 TYR B N   1 
ATOM   3211 C  CA  . TYR B 1 149 ? 25.98851  -22.72291 -29.72400 1.000 30.95903 ? 147 TYR B CA  1 
ATOM   3212 C  C   . TYR B 1 149 ? 25.63247  -23.75373 -30.78777 1.000 31.28997 ? 147 TYR B C   1 
ATOM   3213 O  O   . TYR B 1 149 ? 25.11864  -24.82662 -30.47407 1.000 32.09345 ? 147 TYR B O   1 
ATOM   3214 C  CB  . TYR B 1 149 ? 25.00659  -21.54353 -29.78665 1.000 31.05553 ? 147 TYR B CB  1 
ATOM   3215 C  CG  . TYR B 1 149 ? 23.58704  -22.02143 -29.56827 1.000 33.15255 ? 147 TYR B CG  1 
ATOM   3216 C  CD1 . TYR B 1 149 ? 23.17634  -22.45623 -28.31198 1.000 27.22799 ? 147 TYR B CD1 1 
ATOM   3217 C  CD2 . TYR B 1 149 ? 22.65975  -22.03081 -30.60334 1.000 31.36868 ? 147 TYR B CD2 1 
ATOM   3218 C  CE1 . TYR B 1 149 ? 21.88710  -22.89323 -28.08845 1.000 28.85145 ? 147 TYR B CE1 1 
ATOM   3219 C  CE2 . TYR B 1 149 ? 21.35519  -22.45388 -30.38179 1.000 33.32636 ? 147 TYR B CE2 1 
ATOM   3220 C  CZ  . TYR B 1 149 ? 20.97573  -22.89447 -29.11723 1.000 32.40901 ? 147 TYR B CZ  1 
ATOM   3221 O  OH  . TYR B 1 149 ? 19.68943  -23.36673 -28.89587 1.000 31.40517 ? 147 TYR B OH  1 
ATOM   3222 N  N   . GLU B 1 150 ? 25.85206  -23.40991 -32.05597 1.000 34.75084 ? 148 GLU B N   1 
ATOM   3223 C  CA  . GLU B 1 150 ? 25.57740  -24.31099 -33.16945 1.000 33.15772 ? 148 GLU B CA  1 
ATOM   3224 C  C   . GLU B 1 150 ? 26.17333  -25.69626 -32.93478 1.000 36.80022 ? 148 GLU B C   1 
ATOM   3225 O  O   . GLU B 1 150 ? 25.49065  -26.70840 -33.10026 1.000 35.28023 ? 148 GLU B O   1 
ATOM   3226 C  CB  . GLU B 1 150 ? 26.12539  -23.69220 -34.45359 1.000 35.24462 ? 148 GLU B CB  1 
ATOM   3227 C  CG  . GLU B 1 150 ? 26.37574  -24.63426 -35.60905 1.000 42.54458 ? 148 GLU B CG  1 
ATOM   3228 C  CD  . GLU B 1 150 ? 26.94626  -23.85917 -36.77913 1.000 48.14368 ? 148 GLU B CD  1 
ATOM   3229 O  OE1 . GLU B 1 150 ? 26.14797  -23.27371 -37.54716 1.000 49.55893 ? 148 GLU B OE1 1 
ATOM   3230 O  OE2 . GLU B 1 150 ? 28.18963  -23.79329 -36.90126 1.000 48.27147 ? 148 GLU B OE2 1 
ATOM   3231 N  N   . GLN B 1 151 ? 27.43776  -25.75207 -32.51644 1.000 33.00425 ? 149 GLN B N   1 
ATOM   3232 C  CA  . GLN B 1 151 ? 28.08772  -27.03115 -32.26286 1.000 38.54025 ? 149 GLN B CA  1 
ATOM   3233 C  C   . GLN B 1 151 ? 27.47577  -27.75051 -31.06456 1.000 39.90317 ? 149 GLN B C   1 
ATOM   3234 O  O   . GLN B 1 151 ? 27.39277  -28.98704 -31.05220 1.000 36.55108 ? 149 GLN B O   1 
ATOM   3235 C  CB  . GLN B 1 151 ? 29.58281  -26.80953 -32.05297 1.000 39.19014 ? 149 GLN B CB  1 
ATOM   3236 C  CG  . GLN B 1 151 ? 30.38270  -26.81554 -33.33894 1.000 42.42151 ? 149 GLN B CG  1 
ATOM   3237 C  CD  . GLN B 1 151 ? 31.63913  -25.98790 -33.21856 1.000 48.59145 ? 149 GLN B CD  1 
ATOM   3238 O  OE1 . GLN B 1 151 ? 32.22351  -25.89155 -32.13793 1.000 53.53754 ? 149 GLN B OE1 1 
ATOM   3239 N  NE2 . GLN B 1 151 ? 32.06900  -25.38273 -34.32507 1.000 53.70217 ? 149 GLN B NE2 1 
ATOM   3240 N  N   . ALA B 1 152 ? 27.04732  -27.00989 -30.03522 1.000 34.62292 ? 150 ALA B N   1 
ATOM   3241 C  CA  . ALA B 1 152 ? 26.39797  -27.69003 -28.91842 1.000 34.79034 ? 150 ALA B CA  1 
ATOM   3242 C  C   . ALA B 1 152 ? 25.06639  -28.28595 -29.35835 1.000 35.74537 ? 150 ALA B C   1 
ATOM   3243 O  O   . ALA B 1 152 ? 24.70817  -29.39345 -28.94807 1.000 36.88442 ? 150 ALA B O   1 
ATOM   3244 C  CB  . ALA B 1 152 ? 26.20157  -26.72986 -27.73243 1.000 34.98566 ? 150 ALA B CB  1 
ATOM   3245 N  N   . VAL B 1 153 ? 24.33362  -27.59110 -30.23190 1.000 32.14371 ? 151 VAL B N   1 
ATOM   3246 C  CA  . VAL B 1 153 ? 23.06003  -28.14402 -30.67111 1.000 33.07299 ? 151 VAL B CA  1 
ATOM   3247 C  C   . VAL B 1 153 ? 23.30250  -29.40417 -31.50642 1.000 36.41179 ? 151 VAL B C   1 
ATOM   3248 O  O   . VAL B 1 153 ? 22.55930  -30.38987 -31.41488 1.000 34.48767 ? 151 VAL B O   1 
ATOM   3249 C  CB  . VAL B 1 153 ? 22.26494  -27.07016 -31.42616 1.000 34.37273 ? 151 VAL B CB  1 
ATOM   3250 C  CG1 . VAL B 1 153 ? 21.03750  -27.65346 -32.07388 1.000 33.84128 ? 151 VAL B CG1 1 
ATOM   3251 C  CG2 . VAL B 1 153 ? 21.86300  -25.93779 -30.42558 1.000 30.52836 ? 151 VAL B CG2 1 
ATOM   3252 N  N   . GLU B 1 154 ? 24.37896  -29.39506 -32.28872 1.000 36.91842 ? 152 GLU B N   1 
ATOM   3253 C  CA  . GLU B 1 154 ? 24.73509  -30.52867 -33.13420 1.000 39.67585 ? 152 GLU B CA  1 
ATOM   3254 C  C   . GLU B 1 154 ? 25.09970  -31.75340 -32.30159 1.000 38.98481 ? 152 GLU B C   1 
ATOM   3255 O  O   . GLU B 1 154 ? 24.60798  -32.85909 -32.55569 1.000 41.05298 ? 152 GLU B O   1 
ATOM   3256 C  CB  . GLU B 1 154 ? 25.90939  -30.10955 -33.99525 1.000 44.69646 ? 152 GLU B CB  1 
ATOM   3257 C  CG  . GLU B 1 154 ? 25.60984  -29.98450 -35.44434 1.000 50.82058 ? 152 GLU B CG  1 
ATOM   3258 C  CD  . GLU B 1 154 ? 26.61070  -29.05620 -36.10065 1.000 51.47705 ? 152 GLU B CD  1 
ATOM   3259 O  OE1 . GLU B 1 154 ? 26.16082  -28.21745 -36.90243 1.000 54.90004 ? 152 GLU B OE1 1 
ATOM   3260 O  OE2 . GLU B 1 154 ? 27.83064  -29.14142 -35.80523 1.000 50.13789 ? 152 GLU B OE2 1 
ATOM   3261 N  N   . ARG B 1 155 ? 26.00908  -31.58348 -31.33414 1.000 38.79934 ? 153 ARG B N   1 
ATOM   3262 C  CA  . ARG B 1 155 ? 26.40789  -32.68189 -30.45163 1.000 39.72666 ? 153 ARG B CA  1 
ATOM   3263 C  C   . ARG B 1 155 ? 25.21057  -33.33328 -29.77371 1.000 39.67935 ? 153 ARG B C   1 
ATOM   3264 O  O   . ARG B 1 155 ? 25.21606  -34.53565 -29.51136 1.000 39.61897 ? 153 ARG B O   1 
ATOM   3265 C  CB  . ARG B 1 155 ? 27.39264  -32.16257 -29.39474 1.000 37.73676 ? 153 ARG B CB  1 
ATOM   3266 C  CG  . ARG B 1 155 ? 28.80145  -31.88771 -29.91873 1.000 38.07999 ? 153 ARG B CG  1 
ATOM   3267 C  CD  . ARG B 1 155 ? 29.79318  -31.75675 -28.76823 1.000 38.30700 ? 153 ARG B CD  1 
ATOM   3268 N  NE  . ARG B 1 155 ? 29.39026  -30.70695 -27.83695 1.000 40.29032 ? 153 ARG B NE  1 
ATOM   3269 C  CZ  . ARG B 1 155 ? 29.65443  -29.41581 -28.00746 1.000 40.74364 ? 153 ARG B CZ  1 
ATOM   3270 N  NH1 . ARG B 1 155 ? 30.34079  -28.98436 -29.04739 1.000 38.65282 ? 153 ARG B NH1 1 
ATOM   3271 N  NH2 . ARG B 1 155 ? 29.22300  -28.53593 -27.10608 1.000 38.10448 ? 153 ARG B NH2 1 
ATOM   3272 N  N   . ALA B 1 156 ? 24.17232  -32.56773 -29.49652 1.000 39.79790 ? 154 ALA B N   1 
ATOM   3273 C  CA  . ALA B 1 156 ? 22.97980  -33.09324 -28.84856 1.000 34.78889 ? 154 ALA B CA  1 
ATOM   3274 C  C   . ALA B 1 156 ? 22.00224  -33.68578 -29.84349 1.000 35.98625 ? 154 ALA B C   1 
ATOM   3275 O  O   . ALA B 1 156 ? 20.91865  -34.11447 -29.43997 1.000 39.71755 ? 154 ALA B O   1 
ATOM   3276 C  CB  . ALA B 1 156 ? 22.28187  -31.98126 -28.04365 1.000 36.00021 ? 154 ALA B CB  1 
ATOM   3277 N  N   . GLY B 1 157 ? 22.33922  -33.68724 -31.12934 1.000 34.00935 ? 155 GLY B N   1 
ATOM   3278 C  CA  . GLY B 1 157 ? 21.44311  -34.25848 -32.10971 1.000 36.55100 ? 155 GLY B CA  1 
ATOM   3279 C  C   . GLY B 1 157 ? 20.12580  -33.54284 -32.27684 1.000 37.08946 ? 155 GLY B C   1 
ATOM   3280 O  O   . GLY B 1 157 ? 19.10976  -34.19139 -32.52932 1.000 38.62576 ? 155 GLY B O   1 
ATOM   3281 N  N   . LEU B 1 158 ? 20.10076  -32.22235 -32.11228 1.000 35.96197 ? 156 LEU B N   1 
ATOM   3282 C  CA  . LEU B 1 158 ? 18.88213  -31.45018 -32.27248 1.000 31.74805 ? 156 LEU B CA  1 
ATOM   3283 C  C   . LEU B 1 158 ? 18.98911  -30.55053 -33.49722 1.000 34.38305 ? 156 LEU B C   1 
ATOM   3284 O  O   . LEU B 1 158 ? 20.08046  -30.25745 -33.97767 1.000 34.29129 ? 156 LEU B O   1 
ATOM   3285 C  CB  . LEU B 1 158 ? 18.62205  -30.57513 -31.04054 1.000 33.89837 ? 156 LEU B CB  1 
ATOM   3286 C  CG  . LEU B 1 158 ? 18.57865  -31.37933 -29.73807 1.000 35.63834 ? 156 LEU B CG  1 
ATOM   3287 C  CD1 . LEU B 1 158 ? 18.58622  -30.47420 -28.53267 1.000 34.21487 ? 156 LEU B CD1 1 
ATOM   3288 C  CD2 . LEU B 1 158 ? 17.38628  -32.32269 -29.72352 1.000 37.02759 ? 156 LEU B CD2 1 
ATOM   3289 N  N   . SER B 1 159 ? 17.84174  -30.08067 -33.97566 1.000 34.08830 ? 157 SER B N   1 
ATOM   3290 C  CA  . SER B 1 159 ? 17.78971  -28.93725 -34.87826 1.000 31.91407 ? 157 SER B CA  1 
ATOM   3291 C  C   . SER B 1 159 ? 17.34478  -27.68806 -34.12567 1.000 34.27942 ? 157 SER B C   1 
ATOM   3292 O  O   . SER B 1 159 ? 16.79183  -27.76645 -33.01536 1.000 29.37844 ? 157 SER B O   1 
ATOM   3293 C  CB  . SER B 1 159 ? 16.83925  -29.20412 -36.04615 1.000 33.95477 ? 157 SER B CB  1 
ATOM   3294 O  OG  . SER B 1 159 ? 15.50302  -29.29130 -35.60150 1.000 32.34797 ? 157 SER B OG  1 
ATOM   3295 N  N   . LEU B 1 160 ? 17.58762  -26.52591 -34.75587 1.000 32.31693 ? 158 LEU B N   1 
ATOM   3296 C  CA  . LEU B 1 160 ? 17.05690  -25.26295 -34.23998 1.000 31.93788 ? 158 LEU B CA  1 
ATOM   3297 C  C   . LEU B 1 160 ? 15.53767  -25.28356 -34.23704 1.000 31.08614 ? 158 LEU B C   1 
ATOM   3298 O  O   . LEU B 1 160 ? 14.90133  -24.75351 -33.31952 1.000 33.10848 ? 158 LEU B O   1 
ATOM   3299 C  CB  . LEU B 1 160 ? 17.55386  -24.07870 -35.07906 1.000 32.67682 ? 158 LEU B CB  1 
ATOM   3300 C  CG  . LEU B 1 160 ? 19.06958  -23.86901 -35.07814 1.000 40.28852 ? 158 LEU B CG  1 
ATOM   3301 C  CD1 . LEU B 1 160 ? 19.49903  -22.85242 -36.15127 1.000 40.98135 ? 158 LEU B CD1 1 
ATOM   3302 C  CD2 . LEU B 1 160 ? 19.57535  -23.47671 -33.70289 1.000 37.51038 ? 158 LEU B CD2 1 
ATOM   3303 N  N   . GLN B 1 161 ? 14.92739  -25.89301 -35.25464 1.000 28.46164 ? 159 GLN B N   1 
ATOM   3304 C  CA  . GLN B 1 161 ? 13.47136  -25.96036 -35.24826 1.000 29.89976 ? 159 GLN B CA  1 
ATOM   3305 C  C   . GLN B 1 161 ? 12.97616  -26.67431 -33.99288 1.000 31.76695 ? 159 GLN B C   1 
ATOM   3306 O  O   . GLN B 1 161 ? 11.93019  -26.31150 -33.43638 1.000 30.35116 ? 159 GLN B O   1 
ATOM   3307 C  CB  . GLN B 1 161 ? 12.97292  -26.64424 -36.52415 1.000 28.44312 ? 159 GLN B CB  1 
ATOM   3308 C  CG  . GLN B 1 161 ? 13.00712  -25.70961 -37.77415 1.000 31.86259 ? 159 GLN B CG  1 
ATOM   3309 C  CD  . GLN B 1 161 ? 12.44694  -24.29508 -37.49903 1.000 32.78668 ? 159 GLN B CD  1 
ATOM   3310 O  OE1 . GLN B 1 161 ? 11.29547  -24.15830 -37.08476 1.000 32.02334 ? 159 GLN B OE1 1 
ATOM   3311 N  NE2 . GLN B 1 161 ? 13.26699  -23.24802 -37.72012 1.000 31.86119 ? 159 GLN B NE2 1 
ATOM   3312 N  N   . ASP B 1 162 ? 13.77059  -27.61977 -33.48251 1.000 29.95845 ? 160 ASP B N   1 
ATOM   3313 C  CA  . ASP B 1 162 ? 13.39598  -28.36210 -32.28564 1.000 32.24789 ? 160 ASP B CA  1 
ATOM   3314 C  C   . ASP B 1 162 ? 13.38420  -27.48380 -31.07159 1.000 30.74559 ? 160 ASP B C   1 
ATOM   3315 O  O   . ASP B 1 162 ? 12.43622  -27.51742 -30.27634 1.000 32.23337 ? 160 ASP B O   1 
ATOM   3316 C  CB  . ASP B 1 162 ? 14.39411  -29.47848 -31.99797 1.000 37.29159 ? 160 ASP B CB  1 
ATOM   3317 C  CG  . ASP B 1 162 ? 14.16992  -30.63394 -32.82485 1.000 36.46826 ? 160 ASP B CG  1 
ATOM   3318 O  OD1 . ASP B 1 162 ? 12.99460  -31.00834 -32.92110 1.000 41.72356 ? 160 ASP B OD1 1 
ATOM   3319 O  OD2 . ASP B 1 162 ? 15.17178  -31.21922 -33.27819 1.000 41.61718 ? 160 ASP B OD2 1 
ATOM   3320 N  N   . VAL B 1 163 ? 14.49775  -26.78714 -30.84372 1.000 33.25932 ? 161 VAL B N   1 
ATOM   3321 C  CA  . VAL B 1 163 ? 14.61030  -25.99163 -29.63439 1.000 34.02541 ? 161 VAL B CA  1 
ATOM   3322 C  C   . VAL B 1 163 ? 13.66268  -24.81365 -29.70112 1.000 29.43576 ? 161 VAL B C   1 
ATOM   3323 O  O   . VAL B 1 163 ? 13.13522  -24.39065 -28.66898 1.000 31.17807 ? 161 VAL B O   1 
ATOM   3324 C  CB  . VAL B 1 163 ? 16.08383  -25.59155 -29.39033 1.000 34.47456 ? 161 VAL B CB  1 
ATOM   3325 C  CG1 . VAL B 1 163 ? 16.99625  -26.85667 -29.53910 1.000 36.79009 ? 161 VAL B CG1 1 
ATOM   3326 C  CG2 . VAL B 1 163 ? 16.53337  -24.50503 -30.30191 1.000 38.18341 ? 161 VAL B CG2 1 
ATOM   3327 N  N   . ILE B 1 164 ? 13.38360  -24.29173 -30.90742 1.000 28.90723 ? 162 ILE B N   1 
ATOM   3328 C  CA  . ILE B 1 164 ? 12.35668  -23.25012 -31.03784 1.000 29.84945 ? 162 ILE B CA  1 
ATOM   3329 C  C   . ILE B 1 164 ? 10.99765  -23.79977 -30.62880 1.000 30.99747 ? 162 ILE B C   1 
ATOM   3330 O  O   . ILE B 1 164 ? 10.26352  -23.18020 -29.85208 1.000 28.73564 ? 162 ILE B O   1 
ATOM   3331 C  CB  . ILE B 1 164 ? 12.31779  -22.68454 -32.47460 1.000 32.45236 ? 162 ILE B CB  1 
ATOM   3332 C  CG1 . ILE B 1 164 ? 13.53375  -21.81027 -32.77414 1.000 29.43828 ? 162 ILE B CG1 1 
ATOM   3333 C  CG2 . ILE B 1 164 ? 11.02026  -21.89813 -32.72974 1.000 28.49036 ? 162 ILE B CG2 1 
ATOM   3334 C  CD1 . ILE B 1 164 ? 13.72230  -21.52602 -34.28037 1.000 28.75783 ? 162 ILE B CD1 1 
ATOM   3335 N  N   . ALA B 1 165 ? 10.64984  -24.98188 -31.13249 1.000 28.31266 ? 163 ALA B N   1 
ATOM   3336 C  CA  . ALA B 1 165 ? 9.32773   -25.54501 -30.88378 1.000 30.66931 ? 163 ALA B CA  1 
ATOM   3337 C  C   . ALA B 1 165 ? 9.11374   -25.84905 -29.40263 1.000 30.42072 ? 163 ALA B C   1 
ATOM   3338 O  O   . ALA B 1 165 ? 8.01097   -25.66377 -28.88899 1.000 29.02829 ? 163 ALA B O   1 
ATOM   3339 C  CB  . ALA B 1 165 ? 9.12615   -26.82804 -31.71426 1.000 31.48167 ? 163 ALA B CB  1 
ATOM   3340 N  N   . GLN B 1 166 ? 10.15780  -26.28988 -28.69872 1.000 26.34255 ? 164 GLN B N   1 
ATOM   3341 C  CA  . GLN B 1 166 ? 10.02250  -26.68715 -27.29819 1.000 28.92764 ? 164 GLN B CA  1 
ATOM   3342 C  C   . GLN B 1 166 ? 9.80052   -25.50549 -26.35538 1.000 30.84638 ? 164 GLN B C   1 
ATOM   3343 O  O   . GLN B 1 166 ? 9.53364   -25.72440 -25.16588 1.000 30.54671 ? 164 GLN B O   1 
ATOM   3344 C  CB  . GLN B 1 166 ? 11.26699  -27.47130 -26.88981 1.000 32.84032 ? 164 GLN B CB  1 
ATOM   3345 C  CG  . GLN B 1 166 ? 11.28103  -28.85173 -27.54516 1.000 27.60760 ? 164 GLN B CG  1 
ATOM   3346 C  CD  . GLN B 1 166 ? 12.47422  -29.68394 -27.14566 1.000 33.69731 ? 164 GLN B CD  1 
ATOM   3347 O  OE1 . GLN B 1 166 ? 12.92565  -29.63176 -26.00504 1.000 35.57449 ? 164 GLN B OE1 1 
ATOM   3348 N  NE2 . GLN B 1 166 ? 12.96254  -30.50281 -28.07860 1.000 34.55054 ? 164 GLN B NE2 1 
ATOM   3349 N  N   . GLN B 1 167 ? 9.89710   -24.27044 -26.85181 1.000 28.68781 ? 165 GLN B N   1 
ATOM   3350 C  CA  . GLN B 1 167 ? 9.47588   -23.12119 -26.05163 1.000 28.02189 ? 165 GLN B CA  1 
ATOM   3351 C  C   . GLN B 1 167 ? 7.95582   -23.07231 -25.88127 1.000 28.15887 ? 165 GLN B C   1 
ATOM   3352 O  O   . GLN B 1 167 ? 7.46013   -22.46632 -24.92841 1.000 29.39614 ? 165 GLN B O   1 
ATOM   3353 C  CB  . GLN B 1 167 ? 9.99874   -21.82031 -26.69878 1.000 25.98086 ? 165 GLN B CB  1 
ATOM   3354 C  CG  . GLN B 1 167 ? 10.07580  -20.58115 -25.73028 1.000 29.05694 ? 165 GLN B CG  1 
ATOM   3355 C  CD  . GLN B 1 167 ? 10.23389  -19.23497 -26.45504 1.000 29.99784 ? 165 GLN B CD  1 
ATOM   3356 O  OE1 . GLN B 1 167 ? 10.45423  -19.16890 -27.66898 1.000 31.32379 ? 165 GLN B OE1 1 
ATOM   3357 N  NE2 . GLN B 1 167 ? 10.12416  -18.15912 -25.70829 1.000 30.22802 ? 165 GLN B NE2 1 
ATOM   3358 N  N   . ASP B 1 168 ? 7.20652   -23.68788 -26.78983 1.000 30.98810 ? 166 ASP B N   1 
ATOM   3359 C  CA  . ASP B 1 168 ? 5.74463   -23.70366 -26.74748 1.000 28.85526 ? 166 ASP B CA  1 
ATOM   3360 C  C   . ASP B 1 168 ? 5.26157   -24.87139 -25.87674 1.000 28.53536 ? 166 ASP B C   1 
ATOM   3361 O  O   . ASP B 1 168 ? 5.49949   -26.03924 -26.20532 1.000 29.28816 ? 166 ASP B O   1 
ATOM   3362 C  CB  . ASP B 1 168 ? 5.24975   -23.79354 -28.19788 1.000 31.03461 ? 166 ASP B CB  1 
ATOM   3363 C  CG  . ASP B 1 168 ? 3.73940   -23.91905 -28.33548 1.000 30.72104 ? 166 ASP B CG  1 
ATOM   3364 O  OD1 . ASP B 1 168 ? 3.02829   -23.97956 -27.32679 1.000 30.06004 ? 166 ASP B OD1 1 
ATOM   3365 O  OD2 . ASP B 1 168 ? 3.27222   -24.00102 -29.49387 1.000 30.32505 ? 166 ASP B OD2 1 
ATOM   3366 N  N   . ASP B 1 169 ? 4.59872   -24.55353 -24.74834 1.000 27.44351 ? 167 ASP B N   1 
ATOM   3367 C  CA  . ASP B 1 169 ? 4.09969   -25.57986 -23.84018 1.000 33.56401 ? 167 ASP B CA  1 
ATOM   3368 C  C   . ASP B 1 169 ? 3.17159   -26.56103 -24.56142 1.000 31.58142 ? 167 ASP B C   1 
ATOM   3369 O  O   . ASP B 1 169 ? 3.08823   -27.72633 -24.18388 1.000 31.01995 ? 167 ASP B O   1 
ATOM   3370 C  CB  . ASP B 1 169 ? 3.35057   -24.93682 -22.65138 1.000 30.60948 ? 167 ASP B CB  1 
ATOM   3371 C  CG  . ASP B 1 169 ? 4.28722   -24.33205 -21.56918 1.000 31.10957 ? 167 ASP B CG  1 
ATOM   3372 O  OD1 . ASP B 1 169 ? 5.52373   -24.46033 -21.63162 1.000 29.24072 ? 167 ASP B OD1 1 
ATOM   3373 O  OD2 . ASP B 1 169 ? 3.76013   -23.73675 -20.60147 1.000 31.33909 ? 167 ASP B OD2 1 
ATOM   3374 N  N   . GLY B 1 170 ? 2.44717   -26.10860 -25.57420 1.000 32.50010 ? 168 GLY B N   1 
ATOM   3375 C  CA  . GLY B 1 170 ? 1.57226   -27.03396 -26.26757 1.000 32.77867 ? 168 GLY B CA  1 
ATOM   3376 C  C   . GLY B 1 170 ? 2.23111   -27.87943 -27.33330 1.000 34.58279 ? 168 GLY B C   1 
ATOM   3377 O  O   . GLY B 1 170 ? 1.54571   -28.70491 -27.95155 1.000 33.28428 ? 168 GLY B O   1 
ATOM   3378 N  N   . TYR B 1 171 ? 3.54389   -27.73098 -27.55235 1.000 30.84546 ? 169 TYR B N   1 
ATOM   3379 C  CA  . TYR B 1 171 ? 4.23874   -28.54662 -28.55073 1.000 31.95449 ? 169 TYR B CA  1 
ATOM   3380 C  C   . TYR B 1 171 ? 4.51506   -29.94035 -27.97567 1.000 32.73945 ? 169 TYR B C   1 
ATOM   3381 O  O   . TYR B 1 171 ? 5.10858   -30.05796 -26.89913 1.000 30.19283 ? 169 TYR B O   1 
ATOM   3382 C  CB  . TYR B 1 171 ? 5.54613   -27.88059 -28.98725 1.000 31.90315 ? 169 TYR B CB  1 
ATOM   3383 C  CG  . TYR B 1 171 ? 6.45969   -28.80837 -29.79618 1.000 32.36403 ? 169 TYR B CG  1 
ATOM   3384 C  CD1 . TYR B 1 171 ? 6.13477   -29.16654 -31.09762 1.000 31.56739 ? 169 TYR B CD1 1 
ATOM   3385 C  CD2 . TYR B 1 171 ? 7.63118   -29.32003 -29.24692 1.000 31.99191 ? 169 TYR B CD2 1 
ATOM   3386 C  CE1 . TYR B 1 171 ? 6.95419   -30.02009 -31.83806 1.000 34.14719 ? 169 TYR B CE1 1 
ATOM   3387 C  CE2 . TYR B 1 171 ? 8.45836   -30.17866 -29.97775 1.000 33.05243 ? 169 TYR B CE2 1 
ATOM   3388 C  CZ  . TYR B 1 171 ? 8.11309   -30.50795 -31.27082 1.000 32.79714 ? 169 TYR B CZ  1 
ATOM   3389 O  OH  . TYR B 1 171 ? 8.92044   -31.33202 -32.00155 1.000 36.51421 ? 169 TYR B OH  1 
ATOM   3390 N  N   . ASP B 1 172 ? 4.11653   -30.98722 -28.71173 1.000 30.81253 ? 170 ASP B N   1 
ATOM   3391 C  CA  . ASP B 1 172 ? 4.08182   -32.35790 -28.18307 1.000 35.50306 ? 170 ASP B CA  1 
ATOM   3392 C  C   . ASP B 1 172 ? 5.29661   -33.22720 -28.53890 1.000 37.59814 ? 170 ASP B C   1 
ATOM   3393 O  O   . ASP B 1 172 ? 5.33033   -34.39153 -28.14306 1.000 32.65553 ? 170 ASP B O   1 
ATOM   3394 C  CB  . ASP B 1 172 ? 2.79442   -33.07888 -28.63600 1.000 35.13338 ? 170 ASP B CB  1 
ATOM   3395 C  CG  . ASP B 1 172 ? 2.77396   -33.41404 -30.14810 1.000 42.56179 ? 170 ASP B CG  1 
ATOM   3396 O  OD1 . ASP B 1 172 ? 3.76244   -33.16860 -30.85613 1.000 39.56868 ? 170 ASP B OD1 1 
ATOM   3397 O  OD2 . ASP B 1 172 ? 1.75909   -33.95867 -30.64525 1.000 48.11889 ? 170 ASP B OD2 1 
ATOM   3398 N  N   . GLY B 1 173 ? 6.28830   -32.71807 -29.27271 1.000 34.70147 ? 171 GLY B N   1 
ATOM   3399 C  CA  . GLY B 1 173 ? 7.47304   -33.49887 -29.58125 1.000 36.17102 ? 171 GLY B CA  1 
ATOM   3400 C  C   . GLY B 1 173 ? 8.24584   -33.96053 -28.35856 1.000 36.51106 ? 171 GLY B C   1 
ATOM   3401 O  O   . GLY B 1 173 ? 8.18779   -33.33673 -27.30095 1.000 37.21858 ? 171 GLY B O   1 
ATOM   3402 N  N   . PRO B 1 174 ? 8.97873   -35.07176 -28.46485 1.000 39.93867 ? 172 PRO B N   1 
ATOM   3403 C  CA  . PRO B 1 174 ? 9.69882   -35.57546 -27.28470 1.000 37.80578 ? 172 PRO B CA  1 
ATOM   3404 C  C   . PRO B 1 174 ? 10.80922  -34.61284 -26.88821 1.000 37.64629 ? 172 PRO B C   1 
ATOM   3405 O  O   . PRO B 1 174 ? 11.43686  -33.98374 -27.73772 1.000 39.07908 ? 172 PRO B O   1 
ATOM   3406 C  CB  . PRO B 1 174 ? 10.25438  -36.93221 -27.74506 1.000 40.11288 ? 172 PRO B CB  1 
ATOM   3407 C  CG  . PRO B 1 174 ? 10.31974  -36.83758 -29.24951 1.000 37.39494 ? 172 PRO B CG  1 
ATOM   3408 C  CD  . PRO B 1 174 ? 9.23355   -35.88350 -29.67397 1.000 41.39055 ? 172 PRO B CD  1 
ATOM   3409 N  N   . ARG B 1 175 ? 11.01907  -34.45824 -25.58342 1.000 34.80717 ? 173 ARG B N   1 
ATOM   3410 C  CA  . ARG B 1 175 ? 12.01543  -33.51946 -25.09113 1.000 36.78116 ? 173 ARG B CA  1 
ATOM   3411 C  C   . ARG B 1 175 ? 12.98333  -34.20916 -24.14663 1.000 37.73225 ? 173 ARG B C   1 
ATOM   3412 O  O   . ARG B 1 175 ? 12.69980  -35.27110 -23.60215 1.000 38.45512 ? 173 ARG B O   1 
ATOM   3413 C  CB  . ARG B 1 175 ? 11.37029  -32.34331 -24.35184 1.000 35.11198 ? 173 ARG B CB  1 
ATOM   3414 C  CG  . ARG B 1 175 ? 10.08708  -31.82008 -24.96299 1.000 34.57866 ? 173 ARG B CG  1 
ATOM   3415 C  CD  . ARG B 1 175 ? 9.61757   -30.60683 -24.19095 1.000 35.99622 ? 173 ARG B CD  1 
ATOM   3416 N  NE  . ARG B 1 175 ? 8.42381   -30.02304 -24.78574 1.000 35.44842 ? 173 ARG B NE  1 
ATOM   3417 C  CZ  . ARG B 1 175 ? 7.91479   -28.85461 -24.43941 1.000 32.04427 ? 173 ARG B CZ  1 
ATOM   3418 N  NH1 . ARG B 1 175 ? 8.41408   -28.15327 -23.43325 1.000 36.03151 ? 173 ARG B NH1 1 
ATOM   3419 N  NH2 . ARG B 1 175 ? 6.86132   -28.39024 -25.10032 1.000 32.86590 ? 173 ARG B NH2 1 
ATOM   3420 N  N   . SER B 1 176 ? 14.11885  -33.56978 -23.91606 1.000 37.43193 ? 174 SER B N   1 
ATOM   3421 C  CA  . SER B 1 176 ? 15.02170  -34.00638 -22.86162 1.000 42.24491 ? 174 SER B CA  1 
ATOM   3422 C  C   . SER B 1 176 ? 15.41901  -32.81874 -21.99624 1.000 37.98426 ? 174 SER B C   1 
ATOM   3423 O  O   . SER B 1 176 ? 15.13892  -31.65998 -22.31635 1.000 36.94259 ? 174 SER B O   1 
ATOM   3424 C  CB  . SER B 1 176 ? 16.27715  -34.66542 -23.43322 1.000 36.44523 ? 174 SER B CB  1 
ATOM   3425 O  OG  . SER B 1 176 ? 16.93963  -33.75653 -24.28209 1.000 36.08730 ? 174 SER B OG  1 
ATOM   3426 N  N   . GLY B 1 177 ? 16.10010  -33.13199 -20.89200 1.000 37.25607 ? 175 GLY B N   1 
ATOM   3427 C  CA  . GLY B 1 177 ? 16.74225  -32.08863 -20.11058 1.000 38.43179 ? 175 GLY B CA  1 
ATOM   3428 C  C   . GLY B 1 177 ? 17.67435  -31.23181 -20.94257 1.000 38.07896 ? 175 GLY B C   1 
ATOM   3429 O  O   . GLY B 1 177 ? 17.65934  -30.00219 -20.84244 1.000 36.87139 ? 175 GLY B O   1 
ATOM   3430 N  N   . GLY B 1 178 ? 18.49116  -31.86615 -21.78468 1.000 36.03179 ? 176 GLY B N   1 
ATOM   3431 C  CA  . GLY B 1 178 ? 19.41994  -31.10533 -22.60343 1.000 36.88995 ? 176 GLY B CA  1 
ATOM   3432 C  C   . GLY B 1 178 ? 18.73113  -30.28179 -23.67562 1.000 37.98876 ? 176 GLY B C   1 
ATOM   3433 O  O   . GLY B 1 178 ? 19.13970  -29.14801 -23.95808 1.000 33.48737 ? 176 GLY B O   1 
ATOM   3434 N  N   . SER B 1 179 ? 17.67741  -30.82643 -24.29154 1.000 33.97972 ? 177 SER B N   1 
ATOM   3435 C  CA  . SER B 1 179 ? 17.01441  -30.04165 -25.33249 1.000 35.00037 ? 177 SER B CA  1 
ATOM   3436 C  C   . SER B 1 179 ? 16.34208  -28.80361 -24.75012 1.000 32.87364 ? 177 SER B C   1 
ATOM   3437 O  O   . SER B 1 179 ? 16.36800  -27.72927 -25.36238 1.000 30.37335 ? 177 SER B O   1 
ATOM   3438 C  CB  . SER B 1 179 ? 16.00228  -30.88665 -26.10232 1.000 28.48460 ? 177 SER B CB  1 
ATOM   3439 O  OG  . SER B 1 179 ? 14.88405  -31.19030 -25.32815 1.000 31.32587 ? 177 SER B OG  1 
ATOM   3440 N  N   . GLN B 1 180 ? 15.73820  -28.92571 -23.57047 1.000 31.54773 ? 178 GLN B N   1 
ATOM   3441 C  CA  . GLN B 1 180 ? 15.06777  -27.76566 -23.00577 1.000 30.66072 ? 178 GLN B CA  1 
ATOM   3442 C  C   . GLN B 1 180 ? 16.07640  -26.75236 -22.48628 1.000 31.59121 ? 178 GLN B C   1 
ATOM   3443 O  O   . GLN B 1 180 ? 15.82152  -25.54956 -22.53933 1.000 30.41170 ? 178 GLN B O   1 
ATOM   3444 C  CB  . GLN B 1 180 ? 14.08665  -28.22075 -21.92468 1.000 31.72751 ? 178 GLN B CB  1 
ATOM   3445 C  CG  . GLN B 1 180 ? 13.09056  -29.23499 -22.49160 1.000 31.60917 ? 178 GLN B CG  1 
ATOM   3446 C  CD  . GLN B 1 180 ? 11.84530  -29.39996 -21.67451 1.000 34.73679 ? 178 GLN B CD  1 
ATOM   3447 O  OE1 . GLN B 1 180 ? 10.97335  -28.54124 -21.69408 1.000 30.59004 ? 178 GLN B OE1 1 
ATOM   3448 N  NE2 . GLN B 1 180 ? 11.73208  -30.53442 -20.96736 1.000 29.25019 ? 178 GLN B NE2 1 
ATOM   3449 N  N   . SER B 1 181 ? 17.23348  -27.21482 -22.01625 1.000 31.45462 ? 179 SER B N   1 
ATOM   3450 C  CA  . SER B 1 181 ? 18.29916  -26.29638 -21.63044 1.000 31.76994 ? 179 SER B CA  1 
ATOM   3451 C  C   . SER B 1 181 ? 18.84313  -25.54929 -22.84394 1.000 31.83159 ? 179 SER B C   1 
ATOM   3452 O  O   . SER B 1 181 ? 19.08279  -24.33808 -22.77756 1.000 32.69812 ? 179 SER B O   1 
ATOM   3453 C  CB  . SER B 1 181 ? 19.41178  -27.07229 -20.91663 1.000 34.17412 ? 179 SER B CB  1 
ATOM   3454 O  OG  . SER B 1 181 ? 18.92288  -27.59669 -19.66668 1.000 36.46109 ? 179 SER B OG  1 
ATOM   3455 N  N   . LEU B 1 182 ? 19.02028  -26.23881 -23.97448 1.000 28.06248 ? 180 LEU B N   1 
ATOM   3456 C  CA  . LEU B 1 182 ? 19.47413  -25.52821 -25.16122 1.000 28.07343 ? 180 LEU B CA  1 
ATOM   3457 C  C   . LEU B 1 182 ? 18.40980  -24.56151 -25.66755 1.000 28.99391 ? 180 LEU B C   1 
ATOM   3458 O  O   . LEU B 1 182 ? 18.74685  -23.52740 -26.26249 1.000 30.47519 ? 180 LEU B O   1 
ATOM   3459 C  CB  . LEU B 1 182 ? 19.88129  -26.53260 -26.24960 1.000 32.60341 ? 180 LEU B CB  1 
ATOM   3460 C  CG  . LEU B 1 182 ? 21.23532  -27.17460 -25.92445 1.000 33.61857 ? 180 LEU B CG  1 
ATOM   3461 C  CD1 . LEU B 1 182 ? 21.51087  -28.45607 -26.73061 1.000 35.75198 ? 180 LEU B CD1 1 
ATOM   3462 C  CD2 . LEU B 1 182 ? 22.35486  -26.16891 -26.12268 1.000 28.83312 ? 180 LEU B CD2 1 
ATOM   3463 N  N   . ALA B 1 183 ? 17.13271  -24.87526 -25.44236 1.000 28.60279 ? 181 ALA B N   1 
ATOM   3464 C  CA  . ALA B 1 183 ? 16.06976  -23.93602 -25.77894 1.000 28.79246 ? 181 ALA B CA  1 
ATOM   3465 C  C   . ALA B 1 183 ? 16.19606  -22.64342 -24.96633 1.000 30.31184 ? 181 ALA B C   1 
ATOM   3466 O  O   . ALA B 1 183 ? 16.13896  -21.55600 -25.52740 1.000 29.65108 ? 181 ALA B O   1 
ATOM   3467 C  CB  . ALA B 1 183 ? 14.70218  -24.57296 -25.55405 1.000 25.70326 ? 181 ALA B CB  1 
ATOM   3468 N  N   . LEU B 1 184 ? 16.33663  -22.74567 -23.63758 1.000 28.67957 ? 182 LEU B N   1 
ATOM   3469 C  CA  . LEU B 1 184 ? 16.53985  -21.54208 -22.82973 1.000 29.81462 ? 182 LEU B CA  1 
ATOM   3470 C  C   . LEU B 1 184 ? 17.77417  -20.77680 -23.28630 1.000 30.16277 ? 182 LEU B C   1 
ATOM   3471 O  O   . LEU B 1 184 ? 17.77940  -19.53804 -23.29824 1.000 29.67084 ? 182 LEU B O   1 
ATOM   3472 C  CB  . LEU B 1 184 ? 16.66893  -21.89110 -21.34500 1.000 31.63148 ? 182 LEU B CB  1 
ATOM   3473 C  CG  . LEU B 1 184 ? 15.49366  -22.54458 -20.62276 1.000 33.91854 ? 182 LEU B CG  1 
ATOM   3474 C  CD1 . LEU B 1 184 ? 15.89118  -23.03713 -19.21910 1.000 35.77887 ? 182 LEU B CD1 1 
ATOM   3475 C  CD2 . LEU B 1 184 ? 14.30241  -21.59819 -20.55404 1.000 30.25273 ? 182 LEU B CD2 1 
ATOM   3476 N  N   . VAL B 1 185 ? 18.82454  -21.48875 -23.70013 1.000 31.64928 ? 183 VAL B N   1 
ATOM   3477 C  CA  . VAL B 1 185 ? 19.99839  -20.78963 -24.21154 1.000 33.02081 ? 183 VAL B CA  1 
ATOM   3478 C  C   . VAL B 1 185 ? 19.64042  -19.99647 -25.46104 1.000 32.11248 ? 183 VAL B C   1 
ATOM   3479 O  O   . VAL B 1 185 ? 19.98800  -18.81662 -25.58878 1.000 31.15219 ? 183 VAL B O   1 
ATOM   3480 C  CB  . VAL B 1 185 ? 21.15132  -21.76323 -24.48556 1.000 32.59632 ? 183 VAL B CB  1 
ATOM   3481 C  CG1 . VAL B 1 185 ? 22.27055  -21.00733 -25.20085 1.000 33.66750 ? 183 VAL B CG1 1 
ATOM   3482 C  CG2 . VAL B 1 185 ? 21.65671  -22.32487 -23.18835 1.000 31.13891 ? 183 VAL B CG2 1 
ATOM   3483 N  N   . ARG B 1 186 ? 18.93416  -20.62639 -26.39811 1.000 31.86046 ? 184 ARG B N   1 
ATOM   3484 C  CA  . ARG B 1 186 ? 18.57974  -19.90849 -27.61743 1.000 30.31591 ? 184 ARG B CA  1 
ATOM   3485 C  C   . ARG B 1 186 ? 17.74182  -18.68561 -27.29039 1.000 31.79842 ? 184 ARG B C   1 
ATOM   3486 O  O   . ARG B 1 186 ? 17.94820  -17.60340 -27.86499 1.000 30.72556 ? 184 ARG B O   1 
ATOM   3487 C  CB  . ARG B 1 186 ? 17.82263  -20.81945 -28.58775 1.000 32.13420 ? 184 ARG B CB  1 
ATOM   3488 C  CG  . ARG B 1 186 ? 17.43511  -20.06504 -29.86948 1.000 35.33533 ? 184 ARG B CG  1 
ATOM   3489 C  CD  . ARG B 1 186 ? 16.17783  -20.62344 -30.52245 1.000 33.58496 ? 184 ARG B CD  1 
ATOM   3490 N  NE  . ARG B 1 186 ? 14.98222  -20.44632 -29.70017 1.000 32.31024 ? 184 ARG B NE  1 
ATOM   3491 C  CZ  . ARG B 1 186 ? 14.04208  -19.53609 -29.92481 1.000 35.04567 ? 184 ARG B CZ  1 
ATOM   3492 N  NH1 . ARG B 1 186 ? 14.16236  -18.63900 -30.88790 1.000 33.08032 ? 184 ARG B NH1 1 
ATOM   3493 N  NH2 . ARG B 1 186 ? 12.93733  -19.54726 -29.18410 1.000 32.26169 ? 184 ARG B NH2 1 
ATOM   3494 N  N   . GLU B 1 187 ? 16.82638  -18.81572 -26.32533 1.000 31.08778 ? 185 GLU B N   1 
ATOM   3495 C  CA  . GLU B 1 187 ? 15.94665  -17.68839 -26.01462 1.000 29.44834 ? 185 GLU B CA  1 
ATOM   3496 C  C   . GLU B 1 187 ? 16.72095  -16.53576 -25.38173 1.000 32.82250 ? 185 GLU B C   1 
ATOM   3497 O  O   . GLU B 1 187 ? 16.39982  -15.35684 -25.61925 1.000 29.92818 ? 185 GLU B O   1 
ATOM   3498 C  CB  . GLU B 1 187 ? 14.78955  -18.15666 -25.11248 1.000 29.16554 ? 185 GLU B CB  1 
ATOM   3499 C  CG  . GLU B 1 187 ? 13.90839  -19.21889 -25.76461 1.000 29.75947 ? 185 GLU B CG  1 
ATOM   3500 C  CD  . GLU B 1 187 ? 13.29046  -20.22693 -24.75765 1.000 28.83454 ? 185 GLU B CD  1 
ATOM   3501 O  OE1 . GLU B 1 187 ? 12.93046  -19.81021 -23.62978 1.000 31.11476 ? 185 GLU B OE1 1 
ATOM   3502 O  OE2 . GLU B 1 187 ? 13.16628  -21.42442 -25.11085 1.000 28.83433 ? 185 GLU B OE2 1 
ATOM   3503 N  N   . ALA B 1 188 ? 17.72595  -16.84850 -24.55352 1.000 29.57381 ? 186 ALA B N   1 
ATOM   3504 C  CA  . ALA B 1 188 ? 18.53517  -15.78740 -23.95524 1.000 30.92219 ? 186 ALA B CA  1 
ATOM   3505 C  C   . ALA B 1 188 ? 19.41222  -15.13437 -25.00759 1.000 30.64393 ? 186 ALA B C   1 
ATOM   3506 O  O   . ALA B 1 188 ? 19.62278  -13.90763 -24.99646 1.000 31.02818 ? 186 ALA B O   1 
ATOM   3507 C  CB  . ALA B 1 188 ? 19.39035  -16.34796 -22.82289 1.000 31.54221 ? 186 ALA B CB  1 
ATOM   3508 N  N   . MET B 1 189 ? 19.90548  -15.93523 -25.94676 1.000 31.48238 ? 187 MET B N   1 
ATOM   3509 C  CA  . MET B 1 189 ? 20.71048  -15.38330 -27.02636 1.000 31.44710 ? 187 MET B CA  1 
ATOM   3510 C  C   . MET B 1 189 ? 19.86581  -14.46060 -27.89194 1.000 30.00017 ? 187 MET B C   1 
ATOM   3511 O  O   . MET B 1 189 ? 20.33606  -13.41388 -28.33935 1.000 32.12037 ? 187 MET B O   1 
ATOM   3512 C  CB  . MET B 1 189 ? 21.29873  -16.51081 -27.88409 1.000 31.57123 ? 187 MET B CB  1 
ATOM   3513 C  CG  . MET B 1 189 ? 22.52858  -17.23592 -27.28305 1.000 29.21046 ? 187 MET B CG  1 
ATOM   3514 S  SD  . MET B 1 189 ? 22.96728  -18.68014 -28.29525 1.000 31.26772 ? 187 MET B SD  1 
ATOM   3515 C  CE  . MET B 1 189 ? 23.94666  -17.83728 -29.54187 1.000 34.02828 ? 187 MET B CE  1 
ATOM   3516 N  N   . LEU B 1 190 ? 18.62254  -14.85297 -28.17061 1.000 30.09310 ? 188 LEU B N   1 
ATOM   3517 C  CA  . LEU B 1 190 ? 17.75675  -14.00640 -28.98689 1.000 32.94942 ? 188 LEU B CA  1 
ATOM   3518 C  C   . LEU B 1 190 ? 17.44028  -12.69569 -28.27524 1.000 32.81398 ? 188 LEU B C   1 
ATOM   3519 O  O   . LEU B 1 190 ? 17.39580  -11.62579 -28.90374 1.000 30.48430 ? 188 LEU B O   1 
ATOM   3520 C  CB  . LEU B 1 190 ? 16.47586  -14.76879 -29.34686 1.000 31.36300 ? 188 LEU B CB  1 
ATOM   3521 C  CG  . LEU B 1 190 ? 15.55706  -14.05821 -30.34931 1.000 36.27411 ? 188 LEU B CG  1 
ATOM   3522 C  CD1 . LEU B 1 190 ? 16.26074  -13.86701 -31.69425 1.000 37.53667 ? 188 LEU B CD1 1 
ATOM   3523 C  CD2 . LEU B 1 190 ? 14.26848  -14.84487 -30.55543 1.000 38.93942 ? 188 LEU B CD2 1 
ATOM   3524 N  N   . ARG B 1 191 ? 17.20337  -12.75801 -26.95646 1.000 32.45047 ? 189 ARG B N   1 
ATOM   3525 C  CA  . ARG B 1 191 ? 16.97976  -11.53566 -26.19834 1.000 35.15973 ? 189 ARG B CA  1 
ATOM   3526 C  C   . ARG B 1 191 ? 18.20730  -10.62777 -26.24586 1.000 32.77845 ? 189 ARG B C   1 
ATOM   3527 O  O   . ARG B 1 191 ? 18.08216  -9.39761  -26.36635 1.000 30.14569 ? 189 ARG B O   1 
ATOM   3528 C  CB  . ARG B 1 191 ? 16.59624  -11.88869 -24.75507 1.000 31.61286 ? 189 ARG B CB  1 
ATOM   3529 C  CG  . ARG B 1 191 ? 15.14364  -12.33292 -24.59260 1.000 30.64759 ? 189 ARG B CG  1 
ATOM   3530 C  CD  . ARG B 1 191 ? 14.72660  -12.54749 -23.09751 1.000 34.06327 ? 189 ARG B CD  1 
ATOM   3531 N  NE  . ARG B 1 191 ? 15.60971  -13.45600 -22.35923 1.000 31.88113 ? 189 ARG B NE  1 
ATOM   3532 C  CZ  . ARG B 1 191 ? 15.36700  -14.73842 -22.14084 1.000 32.85870 ? 189 ARG B CZ  1 
ATOM   3533 N  NH1 . ARG B 1 191 ? 14.29774  -15.33349 -22.64526 1.000 35.69291 ? 189 ARG B NH1 1 
ATOM   3534 N  NH2 . ARG B 1 191 ? 16.22176  -15.44295 -21.40316 1.000 30.59019 ? 189 ARG B NH2 1 
ATOM   3535 N  N   . LEU B 1 192 ? 19.40835  -11.20798 -26.15688 1.000 27.41117 ? 190 LEU B N   1 
ATOM   3536 C  CA  . LEU B 1 192 ? 20.60621  -10.38180 -26.24206 1.000 29.31411 ? 190 LEU B CA  1 
ATOM   3537 C  C   . LEU B 1 192 ? 20.69072  -9.69107  -27.60212 1.000 28.98914 ? 190 LEU B C   1 
ATOM   3538 O  O   . LEU B 1 192 ? 20.93892  -8.47558  -27.69265 1.000 30.56264 ? 190 LEU B O   1 
ATOM   3539 C  CB  . LEU B 1 192 ? 21.84461  -11.23961 -25.99836 1.000 31.25988 ? 190 LEU B CB  1 
ATOM   3540 C  CG  . LEU B 1 192 ? 23.16396  -10.54493 -26.32184 1.000 33.79194 ? 190 LEU B CG  1 
ATOM   3541 C  CD1 . LEU B 1 192 ? 23.32092  -9.32256  -25.45843 1.000 32.16276 ? 190 LEU B CD1 1 
ATOM   3542 C  CD2 . LEU B 1 192 ? 24.33851  -11.52652 -26.14937 1.000 33.47700 ? 190 LEU B CD2 1 
ATOM   3543 N  N   . ASP B 1 193 ? 20.45888  -10.45134 -28.67539 1.000 27.44321 ? 191 ASP B N   1 
ATOM   3544 C  CA  . ASP B 1 193 ? 20.57339  -9.88474  -30.02515 1.000 29.09527 ? 191 ASP B CA  1 
ATOM   3545 C  C   . ASP B 1 193 ? 19.48615  -8.84802  -30.26622 1.000 29.06824 ? 191 ASP B C   1 
ATOM   3546 O  O   . ASP B 1 193 ? 19.75174  -7.77644  -30.82797 1.000 28.23633 ? 191 ASP B O   1 
ATOM   3547 C  CB  . ASP B 1 193 ? 20.49959  -11.01964 -31.05929 1.000 25.83720 ? 191 ASP B CB  1 
ATOM   3548 C  CG  . ASP B 1 193 ? 21.22663  -10.70375 -32.37519 1.000 31.07643 ? 191 ASP B CG  1 
ATOM   3549 O  OD1 . ASP B 1 193 ? 21.92144  -9.65821  -32.48605 1.000 29.78532 ? 191 ASP B OD1 1 
ATOM   3550 O  OD2 . ASP B 1 193 ? 21.10549  -11.52949 -33.31382 1.000 28.26692 ? 191 ASP B OD2 1 
ATOM   3551 N  N   . GLY B 1 194 ? 18.25984  -9.13525  -29.80316 1.000 30.54427 ? 192 GLY B N   1 
ATOM   3552 C  CA  . GLY B 1 194 ? 17.20703  -8.12625  -29.82553 1.000 31.27040 ? 192 GLY B CA  1 
ATOM   3553 C  C   . GLY B 1 194 ? 17.59971  -6.85007  -29.10705 1.000 31.48768 ? 192 GLY B C   1 
ATOM   3554 O  O   . GLY B 1 194 ? 17.33338  -5.74693  -29.58885 1.000 28.29446 ? 192 GLY B O   1 
ATOM   3555 N  N   . SER B 1 195 ? 18.23365  -6.97783  -27.94165 1.000 31.82041 ? 193 SER B N   1 
ATOM   3556 C  CA  . SER B 1 195 ? 18.66790  -5.78687  -27.21828 1.000 30.06505 ? 193 SER B CA  1 
ATOM   3557 C  C   . SER B 1 195 ? 19.70388  -4.98621  -28.01374 1.000 27.52420 ? 193 SER B C   1 
ATOM   3558 O  O   . SER B 1 195 ? 19.63375  -3.75782  -28.07928 1.000 31.07608 ? 193 SER B O   1 
ATOM   3559 C  CB  . SER B 1 195 ? 19.23039  -6.16733  -25.85309 1.000 29.57423 ? 193 SER B CB  1 
ATOM   3560 O  OG  . SER B 1 195 ? 19.83015  -5.02378  -25.26135 1.000 30.64977 ? 193 SER B OG  1 
ATOM   3561 N  N   . VAL B 1 196 ? 20.68324  -5.66443  -28.60536 1.000 29.64913 ? 194 VAL B N   1 
ATOM   3562 C  CA  . VAL B 1 196 ? 21.72583  -4.97252  -29.36467 1.000 30.69831 ? 194 VAL B CA  1 
ATOM   3563 C  C   . VAL B 1 196 ? 21.14082  -4.29485  -30.60365 1.000 29.35233 ? 194 VAL B C   1 
ATOM   3564 O  O   . VAL B 1 196 ? 21.54030  -3.17453  -30.97040 1.000 30.40997 ? 194 VAL B O   1 
ATOM   3565 C  CB  . VAL B 1 196 ? 22.85126  -5.96090  -29.71925 1.000 28.64168 ? 194 VAL B CB  1 
ATOM   3566 C  CG1 . VAL B 1 196 ? 23.84310  -5.32162  -30.68432 1.000 34.65766 ? 194 VAL B CG1 1 
ATOM   3567 C  CG2 . VAL B 1 196 ? 23.57030  -6.36365  -28.46130 1.000 30.58903 ? 194 VAL B CG2 1 
ATOM   3568 N  N   . LEU B 1 197 ? 20.20875  -4.96534  -31.28174 1.000 28.73657 ? 195 LEU B N   1 
ATOM   3569 C  CA  . LEU B 1 197 ? 19.49304  -4.34194  -32.39389 1.000 28.82829 ? 195 LEU B CA  1 
ATOM   3570 C  C   . LEU B 1 197 ? 18.72419  -3.11942  -31.91901 1.000 31.88457 ? 195 LEU B C   1 
ATOM   3571 O  O   . LEU B 1 197 ? 18.59239  -2.10958  -32.63956 1.000 31.12886 ? 195 LEU B O   1 
ATOM   3572 C  CB  . LEU B 1 197 ? 18.53959  -5.37151  -33.00241 1.000 30.78606 ? 195 LEU B CB  1 
ATOM   3573 C  CG  . LEU B 1 197 ? 19.07240  -6.43986  -33.93026 1.000 34.34272 ? 195 LEU B CG  1 
ATOM   3574 C  CD1 . LEU B 1 197 ? 17.93527  -7.40679  -34.32444 1.000 30.45934 ? 195 LEU B CD1 1 
ATOM   3575 C  CD2 . LEU B 1 197 ? 19.74515  -5.78362  -35.17922 1.000 33.24356 ? 195 LEU B CD2 1 
ATOM   3576 N  N   . GLY B 1 198 ? 18.20508  -3.19118  -30.69288 1.000 30.93539 ? 196 GLY B N   1 
ATOM   3577 C  CA  . GLY B 1 198 ? 17.59588  -2.02570  -30.10120 1.000 28.77809 ? 196 GLY B CA  1 
ATOM   3578 C  C   . GLY B 1 198 ? 18.59165  -0.91561  -29.84417 1.000 28.15591 ? 196 GLY B C   1 
ATOM   3579 O  O   . GLY B 1 198 ? 18.29727  0.25017   -30.09783 1.000 25.05651 ? 196 GLY B O   1 
ATOM   3580 N  N   . TRP B 1 199 ? 19.77815  -1.25216  -29.32877 1.000 29.25300 ? 197 TRP B N   1 
ATOM   3581 C  CA  . TRP B 1 199 ? 20.80357  -0.21432  -29.20288 1.000 27.05869 ? 197 TRP B CA  1 
ATOM   3582 C  C   . TRP B 1 199 ? 21.02961  0.46664   -30.54700 1.000 26.34025 ? 197 TRP B C   1 
ATOM   3583 O  O   . TRP B 1 199 ? 21.06951  1.69752   -30.62725 1.000 29.37658 ? 197 TRP B O   1 
ATOM   3584 C  CB  . TRP B 1 199 ? 22.13667  -0.77784  -28.66734 1.000 26.14513 ? 197 TRP B CB  1 
ATOM   3585 C  CG  . TRP B 1 199 ? 23.14599  0.34573   -28.57439 1.000 27.63175 ? 197 TRP B CG  1 
ATOM   3586 C  CD1 . TRP B 1 199 ? 23.34441  1.18426   -27.51428 1.000 29.89818 ? 197 TRP B CD1 1 
ATOM   3587 C  CD2 . TRP B 1 199 ? 23.98520  0.84022   -29.63403 1.000 29.74498 ? 197 TRP B CD2 1 
ATOM   3588 N  NE1 . TRP B 1 199 ? 24.29024  2.15045   -27.83277 1.000 31.92503 ? 197 TRP B NE1 1 
ATOM   3589 C  CE2 . TRP B 1 199 ? 24.70715  1.95192   -29.12315 1.000 26.36917 ? 197 TRP B CE2 1 
ATOM   3590 C  CE3 . TRP B 1 199 ? 24.23114  0.42572   -30.94643 1.000 28.65024 ? 197 TRP B CE3 1 
ATOM   3591 C  CZ2 . TRP B 1 199 ? 25.64031  2.67238   -29.89479 1.000 28.26883 ? 197 TRP B CZ2 1 
ATOM   3592 C  CZ3 . TRP B 1 199 ? 25.16131  1.15200   -31.70892 1.000 31.82591 ? 197 TRP B CZ3 1 
ATOM   3593 C  CH2 . TRP B 1 199 ? 25.85489  2.24976   -31.17426 1.000 27.12308 ? 197 TRP B CH2 1 
ATOM   3594 N  N   . LYS B 1 200 ? 21.15391  -0.32662  -31.62414 1.000 27.52479 ? 198 LYS B N   1 
ATOM   3595 C  CA  . LYS B 1 200 ? 21.43254  0.25314   -32.94011 1.000 28.44915 ? 198 LYS B CA  1 
ATOM   3596 C  C   . LYS B 1 200 ? 20.31056  1.17853   -33.39232 1.000 27.85426 ? 198 LYS B C   1 
ATOM   3597 O  O   . LYS B 1 200 ? 20.57455  2.21722   -34.00070 1.000 28.58312 ? 198 LYS B O   1 
ATOM   3598 C  CB  . LYS B 1 200 ? 21.62298  -0.85578  -33.97812 1.000 28.63716 ? 198 LYS B CB  1 
ATOM   3599 C  CG  . LYS B 1 200 ? 22.73658  -1.89035  -33.68091 1.000 34.29836 ? 198 LYS B CG  1 
ATOM   3600 C  CD  . LYS B 1 200 ? 23.14843  -2.68110  -34.93540 1.000 36.15831 ? 198 LYS B CD  1 
ATOM   3601 C  CE  . LYS B 1 200 ? 24.23052  -3.75221  -34.63115 1.000 43.91017 ? 198 LYS B CE  1 
ATOM   3602 N  NZ  . LYS B 1 200 ? 25.35482  -3.88056  -35.62532 1.000 45.88457 ? 198 LYS B NZ  1 
ATOM   3603 N  N   . GLN B 1 201 ? 19.04261  0.80682   -33.14102 1.000 28.81654 ? 199 GLN B N   1 
ATOM   3604 C  CA  . GLN B 1 201 ? 17.94100  1.67368   -33.57635 1.000 28.57432 ? 199 GLN B CA  1 
ATOM   3605 C  C   . GLN B 1 201 ? 17.86947  2.94418   -32.74568 1.000 27.29749 ? 199 GLN B C   1 
ATOM   3606 O  O   . GLN B 1 201 ? 17.58731  4.02478   -33.27396 1.000 28.73750 ? 199 GLN B O   1 
ATOM   3607 C  CB  . GLN B 1 201 ? 16.59795  0.92774   -33.51724 1.000 27.17112 ? 199 GLN B CB  1 
ATOM   3608 C  CG  . GLN B 1 201 ? 16.38691  -0.04899  -34.68002 1.000 30.99813 ? 199 GLN B CG  1 
ATOM   3609 C  CD  . GLN B 1 201 ? 16.77643  0.53339   -36.04368 1.000 34.67274 ? 199 GLN B CD  1 
ATOM   3610 O  OE1 . GLN B 1 201 ? 16.31702  1.59945   -36.42695 1.000 41.71513 ? 199 GLN B OE1 1 
ATOM   3611 N  NE2 . GLN B 1 201 ? 17.61952  -0.17198  -36.76977 1.000 40.48362 ? 199 GLN B NE2 1 
ATOM   3612 N  N   . HIS B 1 202 ? 18.09574  2.83955   -31.43771 1.000 28.75310 ? 200 HIS B N   1 
ATOM   3613 C  CA  . HIS B 1 202 ? 18.04492  4.03217   -30.60192 1.000 28.32617 ? 200 HIS B CA  1 
ATOM   3614 C  C   . HIS B 1 202 ? 19.21419  4.97697   -30.91461 1.000 29.41199 ? 200 HIS B C   1 
ATOM   3615 O  O   . HIS B 1 202 ? 19.05911  6.19749   -30.90029 1.000 27.45617 ? 200 HIS B O   1 
ATOM   3616 C  CB  . HIS B 1 202 ? 18.03861  3.62022   -29.13192 1.000 28.32463 ? 200 HIS B CB  1 
ATOM   3617 C  CG  . HIS B 1 202 ? 16.68330  3.23391   -28.63041 1.000 31.96551 ? 200 HIS B CG  1 
ATOM   3618 N  ND1 . HIS B 1 202 ? 15.64561  4.13058   -28.52366 1.000 32.73334 ? 200 HIS B ND1 1 
ATOM   3619 C  CD2 . HIS B 1 202 ? 16.18959  2.03828   -28.22416 1.000 32.03407 ? 200 HIS B CD2 1 
ATOM   3620 C  CE1 . HIS B 1 202 ? 14.56660  3.50306   -28.08646 1.000 31.15383 ? 200 HIS B CE1 1 
ATOM   3621 N  NE2 . HIS B 1 202 ? 14.87325  2.23964   -27.88712 1.000 35.22957 ? 200 HIS B NE2 1 
ATOM   3622 N  N   . HIS B 1 203 ? 20.39127  4.42510   -31.21065 1.000 28.84572 ? 201 HIS B N   1 
ATOM   3623 C  CA  . HIS B 1 203 ? 21.49470  5.27058   -31.64894 1.000 29.54596 ? 201 HIS B CA  1 
ATOM   3624 C  C   . HIS B 1 203 ? 21.16371  5.92053   -32.99149 1.000 27.89757 ? 201 HIS B C   1 
ATOM   3625 O  O   . HIS B 1 203 ? 21.48032  7.08952   -33.21227 1.000 28.46200 ? 201 HIS B O   1 
ATOM   3626 C  CB  . HIS B 1 203 ? 22.78946  4.43801   -31.69966 1.000 26.57415 ? 201 HIS B CB  1 
ATOM   3627 C  CG  . HIS B 1 203 ? 23.91026  5.08214   -32.45231 1.000 28.84739 ? 201 HIS B CG  1 
ATOM   3628 N  ND1 . HIS B 1 203 ? 24.09389  4.89652   -33.80866 1.000 27.10358 ? 201 HIS B ND1 1 
ATOM   3629 C  CD2 . HIS B 1 203 ? 24.94228  5.85401   -32.03472 1.000 24.21139 ? 201 HIS B CD2 1 
ATOM   3630 C  CE1 . HIS B 1 203 ? 25.15768  5.56625   -34.20324 1.000 30.04526 ? 201 HIS B CE1 1 
ATOM   3631 N  NE2 . HIS B 1 203 ? 25.67858  6.16814   -33.15261 1.000 27.25641 ? 201 HIS B NE2 1 
ATOM   3632 N  N   . LEU B 1 204 ? 20.45888  5.20476   -33.87471 1.000 28.54184 ? 202 LEU B N   1 
ATOM   3633 C  CA  . LEU B 1 204 ? 20.02916  5.82130   -35.13649 1.000 30.59951 ? 202 LEU B CA  1 
ATOM   3634 C  C   . LEU B 1 204 ? 19.02316  6.95594   -34.90907 1.000 29.96002 ? 202 LEU B C   1 
ATOM   3635 O  O   . LEU B 1 204 ? 19.05822  7.99231   -35.59924 1.000 29.76999 ? 202 LEU B O   1 
ATOM   3636 C  CB  . LEU B 1 204 ? 19.42533  4.73954   -36.03355 1.000 31.69495 ? 202 LEU B CB  1 
ATOM   3637 C  CG  . LEU B 1 204 ? 19.21619  5.17357   -37.48486 1.000 36.10263 ? 202 LEU B CG  1 
ATOM   3638 C  CD1 . LEU B 1 204 ? 20.47058  5.86821   -38.05747 1.000 32.59887 ? 202 LEU B CD1 1 
ATOM   3639 C  CD2 . LEU B 1 204 ? 18.83546  3.92899   -38.33077 1.000 38.28280 ? 202 LEU B CD2 1 
ATOM   3640 N  N   . ILE B 1 205 ? 18.09230  6.76753   -33.96906 1.000 30.37875 ? 203 ILE B N   1 
ATOM   3641 C  CA  . ILE B 1 205 ? 17.11747  7.82011   -33.68202 1.000 30.23157 ? 203 ILE B CA  1 
ATOM   3642 C  C   . ILE B 1 205 ? 17.82061  9.03787   -33.10128 1.000 31.58357 ? 203 ILE B C   1 
ATOM   3643 O  O   . ILE B 1 205 ? 17.52200  10.18492  -33.46429 1.000 31.04090 ? 203 ILE B O   1 
ATOM   3644 C  CB  . ILE B 1 205 ? 16.01916  7.30259   -32.73212 1.000 32.53223 ? 203 ILE B CB  1 
ATOM   3645 C  CG1 . ILE B 1 205 ? 15.08476  6.32571   -33.44608 1.000 30.89757 ? 203 ILE B CG1 1 
ATOM   3646 C  CG2 . ILE B 1 205 ? 15.21975  8.47210   -32.16481 1.000 28.90586 ? 203 ILE B CG2 1 
ATOM   3647 C  CD1 . ILE B 1 205 ? 14.31172  5.40733   -32.48074 1.000 28.28655 ? 203 ILE B CD1 1 
ATOM   3648 N  N   . MET B 1 206 ? 18.74356  8.80499   -32.16860 1.000 30.85095 ? 204 MET B N   1 
ATOM   3649 C  CA  . MET B 1 206 ? 19.63003  9.86289   -31.69154 1.000 29.84275 ? 204 MET B CA  1 
ATOM   3650 C  C   . MET B 1 206 ? 20.30984  10.60383  -32.82802 1.000 29.09527 ? 204 MET B C   1 
ATOM   3651 O  O   . MET B 1 206 ? 20.27937  11.83387  -32.87015 1.000 28.12554 ? 204 MET B O   1 
ATOM   3652 C  CB  . MET B 1 206 ? 20.59563  9.25589   -30.67211 1.000 32.21645 ? 204 MET B CB  1 
ATOM   3653 C  CG  . MET B 1 206 ? 21.62314  10.12962  -29.90873 1.000 29.25337 ? 204 MET B CG  1 
ATOM   3654 S  SD  . MET B 1 206 ? 22.85045  10.71254  -31.10280 1.000 35.68167 ? 204 MET B SD  1 
ATOM   3655 C  CE  . MET B 1 206 ? 23.72483  9.12864   -31.05273 1.000 31.54685 ? 204 MET B CE  1 
ATOM   3656 N  N   . VAL B 1 207 ? 20.85568  9.88369   -33.79571 1.000 32.43994 ? 205 VAL B N   1 
ATOM   3657 C  CA  . VAL B 1 207 ? 21.55691  10.57535  -34.87624 1.000 29.64247 ? 205 VAL B CA  1 
ATOM   3658 C  C   . VAL B 1 207 ? 20.59198  11.45705  -35.66544 1.000 28.57642 ? 205 VAL B C   1 
ATOM   3659 O  O   . VAL B 1 207 ? 20.92795  12.58648  -36.02476 1.000 30.03293 ? 205 VAL B O   1 
ATOM   3660 C  CB  . VAL B 1 207 ? 22.30041  9.56792   -35.77563 1.000 31.50162 ? 205 VAL B CB  1 
ATOM   3661 C  CG1 . VAL B 1 207 ? 22.76048  10.23305  -37.08167 1.000 28.93462 ? 205 VAL B CG1 1 
ATOM   3662 C  CG2 . VAL B 1 207 ? 23.51750  9.00206   -35.02902 1.000 28.27538 ? 205 VAL B CG2 1 
ATOM   3663 N  N   . TRP B 1 208 ? 19.36859  10.97897  -35.91367 1.000 30.29149 ? 206 TRP B N   1 
ATOM   3664 C  CA  . TRP B 1 208 ? 18.39682  11.78082  -36.65675 1.000 30.53672 ? 206 TRP B CA  1 
ATOM   3665 C  C   . TRP B 1 208 ? 18.07405  13.07815  -35.93257 1.000 31.75172 ? 206 TRP B C   1 
ATOM   3666 O  O   . TRP B 1 208 ? 17.76585  14.09371  -36.56999 1.000 33.17157 ? 206 TRP B O   1 
ATOM   3667 C  CB  . TRP B 1 208 ? 17.09669  10.99276  -36.86820 1.000 30.13842 ? 206 TRP B CB  1 
ATOM   3668 C  CG  . TRP B 1 208 ? 17.25707  9.73199   -37.68265 1.000 33.94620 ? 206 TRP B CG  1 
ATOM   3669 C  CD1 . TRP B 1 208 ? 18.23715  9.45447   -38.58677 1.000 37.07200 ? 206 TRP B CD1 1 
ATOM   3670 C  CD2 . TRP B 1 208 ? 16.39193  8.59315   -37.66504 1.000 36.21092 ? 206 TRP B CD2 1 
ATOM   3671 N  NE1 . TRP B 1 208 ? 18.03979  8.20438   -39.12380 1.000 37.76514 ? 206 TRP B NE1 1 
ATOM   3672 C  CE2 . TRP B 1 208 ? 16.91056  7.65895   -38.57528 1.000 39.96645 ? 206 TRP B CE2 1 
ATOM   3673 C  CE3 . TRP B 1 208 ? 15.22258  8.27788   -36.96585 1.000 37.17413 ? 206 TRP B CE3 1 
ATOM   3674 C  CZ2 . TRP B 1 208 ? 16.30726  6.41065   -38.80330 1.000 41.28364 ? 206 TRP B CZ2 1 
ATOM   3675 C  CZ3 . TRP B 1 208 ? 14.61974  7.02387   -37.19170 1.000 41.92103 ? 206 TRP B CZ3 1 
ATOM   3676 C  CH2 . TRP B 1 208 ? 15.16647  6.11879   -38.10181 1.000 41.89001 ? 206 TRP B CH2 1 
ATOM   3677 N  N   . SER B 1 209 ? 18.11996  13.06702  -34.60480 1.000 27.98123 ? 207 SER B N   1 
ATOM   3678 C  CA  . SER B 1 209 ? 17.80319  14.26240  -33.84211 1.000 31.42475 ? 207 SER B CA  1 
ATOM   3679 C  C   . SER B 1 209 ? 18.99056  15.20456  -33.66877 1.000 30.96244 ? 207 SER B C   1 
ATOM   3680 O  O   . SER B 1 209 ? 18.79376  16.35100  -33.24788 1.000 30.69284 ? 207 SER B O   1 
ATOM   3681 C  CB  . SER B 1 209 ? 17.25433  13.85617  -32.46203 1.000 28.14552 ? 207 SER B CB  1 
ATOM   3682 O  OG  . SER B 1 209 ? 18.29979  13.33181  -31.66201 1.000 30.47752 ? 207 SER B OG  1 
ATOM   3683 N  N   . GLN B 1 210 ? 20.21032  14.74840  -33.94434 1.000 31.45692 ? 208 GLN B N   1 
ATOM   3684 C  CA  . GLN B 1 210 ? 21.41108  15.56308  -33.77699 1.000 30.40988 ? 208 GLN B CA  1 
ATOM   3685 C  C   . GLN B 1 210 ? 22.04526  15.97215  -35.09434 1.000 29.42475 ? 208 GLN B C   1 
ATOM   3686 O  O   . GLN B 1 210 ? 22.57600  17.07369  -35.19675 1.000 30.82280 ? 208 GLN B O   1 
ATOM   3687 C  CB  . GLN B 1 210 ? 22.45757  14.80889  -32.94138 1.000 27.79666 ? 208 GLN B CB  1 
ATOM   3688 C  CG  . GLN B 1 210 ? 21.83186  14.35022  -31.62619 1.000 30.35781 ? 208 GLN B CG  1 
ATOM   3689 C  CD  . GLN B 1 210 ? 21.92942  15.48393  -30.60734 1.000 33.63871 ? 208 GLN B CD  1 
ATOM   3690 O  OE1 . GLN B 1 210 ? 22.90417  16.20215  -30.59512 1.000 30.55251 ? 208 GLN B OE1 1 
ATOM   3691 N  NE2 . GLN B 1 210 ? 20.89934  15.67073  -29.80199 1.000 32.10524 ? 208 GLN B NE2 1 
ATOM   3692 N  N   . LEU B 1 211 ? 21.97550  15.12274  -36.10769 1.000 31.44630 ? 209 LEU B N   1 
ATOM   3693 C  CA  . LEU B 1 211 ? 22.52909  15.43646  -37.41334 1.000 32.91048 ? 209 LEU B CA  1 
ATOM   3694 C  C   . LEU B 1 211 ? 21.49746  15.50741  -38.52762 1.000 34.89436 ? 209 LEU B C   1 
ATOM   3695 O  O   . LEU B 1 211 ? 21.81643  16.02064  -39.60095 1.000 34.14097 ? 209 LEU B O   1 
ATOM   3696 C  CB  . LEU B 1 211 ? 23.58945  14.39063  -37.80163 1.000 28.70498 ? 209 LEU B CB  1 
ATOM   3697 C  CG  . LEU B 1 211 ? 24.80550  14.22645  -36.87684 1.000 32.26653 ? 209 LEU B CG  1 
ATOM   3698 C  CD1 . LEU B 1 211 ? 25.83080  13.21342  -37.46493 1.000 32.57813 ? 209 LEU B CD1 1 
ATOM   3699 C  CD2 . LEU B 1 211 ? 25.46514  15.56145  -36.54942 1.000 29.23789 ? 209 LEU B CD2 1 
ATOM   3700 N  N   . GLY B 1 212 ? 20.31104  14.94882  -38.34151 1.000 35.97418 ? 210 GLY B N   1 
ATOM   3701 C  CA  . GLY B 1 212 ? 19.31686  14.92904  -39.38654 1.000 35.80288 ? 210 GLY B CA  1 
ATOM   3702 C  C   . GLY B 1 212 ? 19.23583  13.59652  -40.10750 1.000 33.30847 ? 210 GLY B C   1 
ATOM   3703 O  O   . GLY B 1 212 ? 19.69001  12.54883  -39.63563 1.000 32.11592 ? 210 GLY B O   1 
ATOM   3704 N  N   . GLY B 1 213 ? 18.60198  13.64279  -41.27388 1.000 35.37219 ? 211 GLY B N   1 
ATOM   3705 C  CA  . GLY B 1 213 ? 18.42947  12.44464  -42.07304 1.000 35.43398 ? 211 GLY B CA  1 
ATOM   3706 C  C   . GLY B 1 213 ? 17.30068  11.51373  -41.68703 1.000 36.81597 ? 211 GLY B C   1 
ATOM   3707 O  O   . GLY B 1 213 ? 17.27559  10.38247  -42.17280 1.000 36.50291 ? 211 GLY B O   1 
ATOM   3708 N  N   . GLN B 1 214 ? 16.36497  11.93817  -40.83878 1.000 37.12951 ? 212 GLN B N   1 
ATOM   3709 C  CA  . GLN B 1 214 ? 15.20549  11.11128  -40.51692 1.000 36.87341 ? 212 GLN B CA  1 
ATOM   3710 C  C   . GLN B 1 214 ? 14.54108  10.63300  -41.80732 1.000 39.10898 ? 212 GLN B C   1 
ATOM   3711 O  O   . GLN B 1 214 ? 14.09821  11.46980  -42.61049 1.000 36.26153 ? 212 GLN B O   1 
ATOM   3712 C  CB  . GLN B 1 214 ? 14.18783  11.87558  -39.66632 1.000 32.71412 ? 212 GLN B CB  1 
ATOM   3713 C  CG  . GLN B 1 214 ? 13.41944  10.98201  -38.69796 1.000 34.89565 ? 212 GLN B CG  1 
ATOM   3714 C  CD  . GLN B 1 214 ? 12.39725  10.10429  -39.41533 1.000 36.05341 ? 212 GLN B CD  1 
ATOM   3715 O  OE1 . GLN B 1 214 ? 11.75958  10.53532  -40.36785 1.000 34.49738 ? 212 GLN B OE1 1 
ATOM   3716 N  NE2 . GLN B 1 214 ? 12.27251  8.85776   -38.98045 1.000 34.71868 ? 212 GLN B NE2 1 
ATOM   3717 N  N   . PRO B 1 215 ? 14.44647  9.30867   -42.03181 1.000 41.58978 ? 213 PRO B N   1 
ATOM   3718 C  CA  . PRO B 1 215 ? 14.05825  8.77983   -43.35326 1.000 42.24957 ? 213 PRO B CA  1 
ATOM   3719 C  C   . PRO B 1 215 ? 12.65198  9.11545   -43.79059 1.000 41.38333 ? 213 PRO B C   1 
ATOM   3720 O  O   . PRO B 1 215 ? 12.38095  9.05551   -44.99325 1.000 40.04007 ? 213 PRO B O   1 
ATOM   3721 C  CB  . PRO B 1 215 ? 14.18894  7.25651   -43.17636 1.000 43.64525 ? 213 PRO B CB  1 
ATOM   3722 C  CG  . PRO B 1 215 ? 15.01614  7.06220   -41.97874 1.000 45.17158 ? 213 PRO B CG  1 
ATOM   3723 C  CD  . PRO B 1 215 ? 14.73903  8.23097   -41.08283 1.000 38.32188 ? 213 PRO B CD  1 
ATOM   3724 N  N   . GLY B 1 216 ? 11.72895  9.39451   -42.87429 1.000 39.82888 ? 214 GLY B N   1 
ATOM   3725 C  CA  . GLY B 1 216 ? 10.39990  9.79731   -43.30788 1.000 43.02742 ? 214 GLY B CA  1 
ATOM   3726 C  C   . GLY B 1 216 ? 10.41182  11.08635  -44.11104 1.000 49.00054 ? 214 GLY B C   1 
ATOM   3727 O  O   . GLY B 1 216 ? 9.51048   11.33083  -44.92107 1.000 54.91096 ? 214 GLY B O   1 
ATOM   3728 N  N   . LEU B 1 217 ? 11.43819  11.91548  -43.91614 1.000 44.56278 ? 215 LEU B N   1 
ATOM   3729 C  CA  . LEU B 1 217 ? 11.55688  13.19729  -44.59981 1.000 47.86606 ? 215 LEU B CA  1 
ATOM   3730 C  C   . LEU B 1 217 ? 11.73309  13.06557  -46.11095 1.000 53.39211 ? 215 LEU B C   1 
ATOM   3731 O  O   . LEU B 1 217 ? 11.83991  14.08599  -46.80674 1.000 49.60622 ? 215 LEU B O   1 
ATOM   3732 C  CB  . LEU B 1 217 ? 12.73145  13.99014  -44.02245 1.000 48.48645 ? 215 LEU B CB  1 
ATOM   3733 C  CG  . LEU B 1 217 ? 12.74591  14.27712  -42.51125 1.000 42.38489 ? 215 LEU B CG  1 
ATOM   3734 C  CD1 . LEU B 1 217 ? 14.06347  14.91967  -42.09686 1.000 30.73868 ? 215 LEU B CD1 1 
ATOM   3735 C  CD2 . LEU B 1 217 ? 11.55609  15.13710  -42.10441 1.000 39.46989 ? 215 LEU B CD2 1 
ATOM   3736 N  N   . LEU B 1 230 ? 22.27742  13.77033  -48.16946 1.000 46.75265 ? 228 LEU B N   1 
ATOM   3737 C  CA  . LEU B 1 230 ? 22.21228  13.48187  -46.73139 1.000 46.27193 ? 228 LEU B CA  1 
ATOM   3738 C  C   . LEU B 1 230 ? 23.40775  14.03295  -45.96416 1.000 42.98196 ? 228 LEU B C   1 
ATOM   3739 O  O   . LEU B 1 230 ? 24.49943  14.13888  -46.51701 1.000 45.34698 ? 228 LEU B O   1 
ATOM   3740 C  CB  . LEU B 1 230 ? 22.13551  11.96602  -46.47164 1.000 45.23106 ? 228 LEU B CB  1 
ATOM   3741 C  CG  . LEU B 1 230 ? 20.92951  11.12311  -46.89668 1.000 45.69863 ? 228 LEU B CG  1 
ATOM   3742 C  CD1 . LEU B 1 230 ? 21.19684  9.66902   -46.56709 1.000 44.26815 ? 228 LEU B CD1 1 
ATOM   3743 C  CD2 . LEU B 1 230 ? 19.66030  11.58062  -46.18231 1.000 43.07901 ? 228 LEU B CD2 1 
ATOM   3744 N  N   . PRO B 1 231 ? 23.20104  14.34360  -44.67432 1.000 37.71491 ? 229 PRO B N   1 
ATOM   3745 C  CA  . PRO B 1 231 ? 24.33021  14.62944  -43.77440 1.000 39.72039 ? 229 PRO B CA  1 
ATOM   3746 C  C   . PRO B 1 231 ? 25.43493  13.56974  -43.74782 1.000 40.97521 ? 229 PRO B C   1 
ATOM   3747 O  O   . PRO B 1 231 ? 25.22386  12.40001  -44.09934 1.000 42.49288 ? 229 PRO B O   1 
ATOM   3748 C  CB  . PRO B 1 231 ? 23.65611  14.73354  -42.39729 1.000 35.05174 ? 229 PRO B CB  1 
ATOM   3749 C  CG  . PRO B 1 231 ? 22.24104  15.15448  -42.68730 1.000 37.32007 ? 229 PRO B CG  1 
ATOM   3750 C  CD  . PRO B 1 231 ? 21.89208  14.54424  -44.02569 1.000 40.28593 ? 229 PRO B CD  1 
ATOM   3751 N  N   . GLN B 1 232 ? 26.61312  13.97566  -43.26954 1.000 40.15265 ? 230 GLN B N   1 
ATOM   3752 C  CA  . GLN B 1 232 ? 27.80287  13.13603  -43.22939 1.000 41.25807 ? 230 GLN B CA  1 
ATOM   3753 C  C   . GLN B 1 232 ? 28.34265  13.00145  -41.81131 1.000 41.51184 ? 230 GLN B C   1 
ATOM   3754 O  O   . GLN B 1 232 ? 28.35476  13.97460  -41.04196 1.000 40.18520 ? 230 GLN B O   1 
ATOM   3755 C  CB  . GLN B 1 232 ? 28.91150  13.71277  -44.11245 1.000 42.37422 ? 230 GLN B CB  1 
ATOM   3756 C  CG  . GLN B 1 232 ? 28.66554  13.61184  -45.60940 1.000 46.76073 ? 230 GLN B CG  1 
ATOM   3757 C  CD  . GLN B 1 232 ? 29.65979  14.45224  -46.42068 1.000 49.36772 ? 230 GLN B CD  1 
ATOM   3758 O  OE1 . GLN B 1 232 ? 30.65406  14.95982  -45.88317 1.000 48.17826 ? 230 GLN B OE1 1 
ATOM   3759 N  NE2 . GLN B 1 232 ? 29.39544  14.59191  -47.72000 1.000 50.33691 ? 230 GLN B NE2 1 
ATOM   3760 N  N   . SER B 1 233 ? 28.83478  11.80265  -41.49019 1.000 39.66498 ? 231 SER B N   1 
ATOM   3761 C  CA  . SER B 1 233 ? 29.63566  11.58049  -40.29212 1.000 37.30592 ? 231 SER B CA  1 
ATOM   3762 C  C   . SER B 1 233 ? 30.92392  12.40736  -40.33979 1.000 41.00042 ? 231 SER B C   1 
ATOM   3763 O  O   . SER B 1 233 ? 31.32151  12.94898  -41.37880 1.000 39.84593 ? 231 SER B O   1 
ATOM   3764 C  CB  . SER B 1 233 ? 30.03237  10.10897  -40.17112 1.000 39.83073 ? 231 SER B CB  1 
ATOM   3765 O  OG  . SER B 1 233 ? 31.13615  9.85019   -41.03315 1.000 39.97667 ? 231 SER B OG  1 
ATOM   3766 N  N   . LEU B 1 234 ? 31.62304  12.44370  -39.20608 1.000 38.09795 ? 232 LEU B N   1 
ATOM   3767 C  CA  . LEU B 1 234 ? 32.96312  13.01295  -39.22550 1.000 43.17089 ? 232 LEU B CA  1 
ATOM   3768 C  C   . LEU B 1 234 ? 33.89185  12.20938  -40.13724 1.000 42.91010 ? 232 LEU B C   1 
ATOM   3769 O  O   . LEU B 1 234 ? 34.90295  12.73485  -40.59318 1.000 46.46812 ? 232 LEU B O   1 
ATOM   3770 C  CB  . LEU B 1 234 ? 33.52582  13.08690  -37.80487 1.000 41.10872 ? 232 LEU B CB  1 
ATOM   3771 C  CG  . LEU B 1 234 ? 32.84280  14.04247  -36.82138 1.000 39.83269 ? 232 LEU B CG  1 
ATOM   3772 C  CD1 . LEU B 1 234 ? 33.60803  14.03870  -35.51882 1.000 39.93273 ? 232 LEU B CD1 1 
ATOM   3773 C  CD2 . LEU B 1 234 ? 32.76505  15.45801  -37.38328 1.000 38.35356 ? 232 LEU B CD2 1 
ATOM   3774 N  N   . GLY B 1 235 ? 33.55237  10.96874  -40.45130 1.000 45.50106 ? 233 GLY B N   1 
ATOM   3775 C  CA  . GLY B 1 235 ? 34.34812  10.23879  -41.41171 1.000 47.93832 ? 233 GLY B CA  1 
ATOM   3776 C  C   . GLY B 1 235 ? 34.10908  10.63729  -42.84763 1.000 48.94792 ? 233 GLY B C   1 
ATOM   3777 O  O   . GLY B 1 235 ? 34.80996  10.15657  -43.74106 1.000 50.95631 ? 233 GLY B O   1 
ATOM   3778 N  N   . GLY B 1 236 ? 33.13182  11.50145  -43.09478 1.000 46.11369 ? 234 GLY B N   1 
ATOM   3779 C  CA  . GLY B 1 236 ? 32.75976  11.85279  -44.44443 1.000 47.55835 ? 234 GLY B CA  1 
ATOM   3780 C  C   . GLY B 1 236 ? 31.71411  10.95304  -45.05893 1.000 45.34235 ? 234 GLY B C   1 
ATOM   3781 O  O   . GLY B 1 236 ? 31.35537  11.15289  -46.22320 1.000 46.51172 ? 234 GLY B O   1 
ATOM   3782 N  N   . ARG B 1 237 ? 31.20036  9.98292   -44.31588 1.000 42.79027 ? 235 ARG B N   1 
ATOM   3783 C  CA  . ARG B 1 237 ? 30.28831  8.99057   -44.87333 1.000 44.66452 ? 235 ARG B CA  1 
ATOM   3784 C  C   . ARG B 1 237 ? 28.83662  9.42973   -44.70139 1.000 44.11852 ? 235 ARG B C   1 
ATOM   3785 O  O   . ARG B 1 237 ? 28.44205  9.93985   -43.64131 1.000 44.90857 ? 235 ARG B O   1 
ATOM   3786 C  CB  . ARG B 1 237 ? 30.52443  7.61925   -44.22207 1.000 42.87364 ? 235 ARG B CB  1 
ATOM   3787 C  CG  . ARG B 1 237 ? 31.87688  6.99445   -44.61200 1.000 49.93929 ? 235 ARG B CG  1 
ATOM   3788 C  CD  . ARG B 1 237 ? 32.28384  5.73811   -43.78978 1.000 51.22283 ? 235 ARG B CD  1 
ATOM   3789 N  NE  . ARG B 1 237 ? 32.64820  6.07228   -42.41619 1.000 55.43214 ? 235 ARG B NE  1 
ATOM   3790 C  CZ  . ARG B 1 237 ? 33.89277  6.21808   -41.97469 1.000 54.82450 ? 235 ARG B CZ  1 
ATOM   3791 N  NH1 . ARG B 1 237 ? 34.93604  6.00622   -42.76115 1.000 56.53676 ? 235 ARG B NH1 1 
ATOM   3792 N  NH2 . ARG B 1 237 ? 34.09417  6.61298   -40.71732 1.000 52.87335 ? 235 ARG B NH2 1 
ATOM   3793 N  N   . SER B 1 238 ? 28.04546  9.24094   -45.75793 1.000 41.15910 ? 236 SER B N   1 
ATOM   3794 C  CA  . SER B 1 238 ? 26.61164  9.48744   -45.67431 1.000 43.89219 ? 236 SER B CA  1 
ATOM   3795 C  C   . SER B 1 238 ? 26.00723  8.69968   -44.51132 1.000 44.64132 ? 236 SER B C   1 
ATOM   3796 O  O   . SER B 1 238 ? 26.50611  7.63327   -44.13052 1.000 43.22177 ? 236 SER B O   1 
ATOM   3797 C  CB  . SER B 1 238 ? 25.93235  9.08987   -46.98506 1.000 44.14309 ? 236 SER B CB  1 
ATOM   3798 O  OG  . SER B 1 238 ? 24.51993  9.01902   -46.83820 1.000 45.42622 ? 236 SER B OG  1 
ATOM   3799 N  N   . LEU B 1 239 ? 24.92458  9.23555   -43.93801 1.000 41.58040 ? 237 LEU B N   1 
ATOM   3800 C  CA  . LEU B 1 239 ? 24.22513  8.51581   -42.87493 1.000 41.19428 ? 237 LEU B CA  1 
ATOM   3801 C  C   . LEU B 1 239 ? 23.52578  7.28196   -43.40416 1.000 40.88631 ? 237 LEU B C   1 
ATOM   3802 O  O   . LEU B 1 239 ? 23.13639  6.42190   -42.61356 1.000 37.98453 ? 237 LEU B O   1 
ATOM   3803 C  CB  . LEU B 1 239 ? 23.19617  9.41518   -42.19359 1.000 42.69379 ? 237 LEU B CB  1 
ATOM   3804 C  CG  . LEU B 1 239 ? 23.77017  10.61869  -41.44741 1.000 40.66948 ? 237 LEU B CG  1 
ATOM   3805 C  CD1 . LEU B 1 239 ? 22.65615  11.47243  -40.90804 1.000 37.26544 ? 237 LEU B CD1 1 
ATOM   3806 C  CD2 . LEU B 1 239 ? 24.68479  10.13884  -40.33354 1.000 42.57791 ? 237 LEU B CD2 1 
ATOM   3807 N  N   . ALA B 1 240 ? 23.34860  7.18806   -44.72430 1.000 41.00255 ? 238 ALA B N   1 
ATOM   3808 C  CA  . ALA B 1 240 ? 22.79956  5.97716   -45.32230 1.000 41.67852 ? 238 ALA B CA  1 
ATOM   3809 C  C   . ALA B 1 240 ? 23.60675  4.74893   -44.94094 1.000 38.63009 ? 238 ALA B C   1 
ATOM   3810 O  O   . ALA B 1 240 ? 23.04415  3.65406   -44.78584 1.000 40.17204 ? 238 ALA B O   1 
ATOM   3811 C  CB  . ALA B 1 240 ? 22.75044  6.11868   -46.84632 1.000 39.47083 ? 238 ALA B CB  1 
ATOM   3812 N  N   . THR B 1 241 ? 24.91590  4.90146   -44.75909 1.000 36.52746 ? 239 THR B N   1 
ATOM   3813 C  CA  . THR B 1 241 ? 25.72807  3.73377   -44.41696 1.000 36.71380 ? 239 THR B CA  1 
ATOM   3814 C  C   . THR B 1 241 ? 25.47009  3.29878   -42.98085 1.000 37.64488 ? 239 THR B C   1 
ATOM   3815 O  O   . THR B 1 241 ? 25.25093  2.11320   -42.70868 1.000 38.73988 ? 239 THR B O   1 
ATOM   3816 C  CB  . THR B 1 241 ? 27.21098  4.04619   -44.65990 1.000 43.03429 ? 239 THR B CB  1 
ATOM   3817 O  OG1 . THR B 1 241 ? 27.65043  5.06984   -43.76151 1.000 45.97132 ? 239 THR B OG1 1 
ATOM   3818 C  CG2 . THR B 1 241 ? 27.40575  4.56252   -46.09035 1.000 43.08192 ? 239 THR B CG2 1 
ATOM   3819 N  N   . LEU B 1 242 ? 25.46116  4.25339   -42.04549 1.000 37.36742 ? 240 LEU B N   1 
ATOM   3820 C  CA  . LEU B 1 242 ? 25.05341  3.94925   -40.67465 1.000 34.54393 ? 240 LEU B CA  1 
ATOM   3821 C  C   . LEU B 1 242 ? 23.71871  3.21014   -40.64589 1.000 35.89840 ? 240 LEU B C   1 
ATOM   3822 O  O   . LEU B 1 242 ? 23.57566  2.17316   -39.98895 1.000 34.67845 ? 240 LEU B O   1 
ATOM   3823 C  CB  . LEU B 1 242 ? 24.95744  5.25147   -39.86646 1.000 32.96514 ? 240 LEU B CB  1 
ATOM   3824 C  CG  . LEU B 1 242 ? 24.44010  5.10355   -38.43476 1.000 32.29946 ? 240 LEU B CG  1 
ATOM   3825 C  CD1 . LEU B 1 242 ? 25.42031  4.32043   -37.58621 1.000 32.89971 ? 240 LEU B CD1 1 
ATOM   3826 C  CD2 . LEU B 1 242 ? 24.14703  6.47354   -37.80741 1.000 28.36347 ? 240 LEU B CD2 1 
ATOM   3827 N  N   . GLU B 1 243 ? 22.71947  3.74168   -41.34836 1.000 34.93670 ? 241 GLU B N   1 
ATOM   3828 C  CA  . GLU B 1 243 ? 21.39294  3.13268   -41.30390 1.000 37.46512 ? 241 GLU B CA  1 
ATOM   3829 C  C   . GLU B 1 243 ? 21.39098  1.71092   -41.86311 1.000 37.92357 ? 241 GLU B C   1 
ATOM   3830 O  O   . GLU B 1 243 ? 20.63012  0.85523   -41.38572 1.000 34.87957 ? 241 GLU B O   1 
ATOM   3831 C  CB  . GLU B 1 243 ? 20.39579  4.01025   -42.06503 1.000 36.42485 ? 241 GLU B CB  1 
ATOM   3832 C  CG  . GLU B 1 243 ? 18.99883  3.43767   -42.04879 1.000 38.35055 ? 241 GLU B CG  1 
ATOM   3833 C  CD  . GLU B 1 243 ? 18.04083  4.18687   -42.93884 1.000 43.56547 ? 241 GLU B CD  1 
ATOM   3834 O  OE1 . GLU B 1 243 ? 18.40628  5.28818   -43.39901 1.000 45.26922 ? 241 GLU B OE1 1 
ATOM   3835 O  OE2 . GLU B 1 243 ? 16.92100  3.67288   -43.17035 1.000 46.54157 ? 241 GLU B OE2 1 
ATOM   3836 N  N   . ALA B 1 244 ? 22.22469  1.42827   -42.87130 1.000 41.10003 ? 242 ALA B N   1 
ATOM   3837 C  CA  . ALA B 1 244 ? 22.24279  0.07037   -43.42451 1.000 39.40685 ? 242 ALA B CA  1 
ATOM   3838 C  C   . ALA B 1 244 ? 22.89377  -0.91931  -42.46283 1.000 38.15471 ? 242 ALA B C   1 
ATOM   3839 O  O   . ALA B 1 244 ? 22.42542  -2.05364  -42.32976 1.000 44.00489 ? 242 ALA B O   1 
ATOM   3840 C  CB  . ALA B 1 244 ? 22.95191  0.04522   -44.77664 1.000 39.73200 ? 242 ALA B CB  1 
ATOM   3841 N  N   . ARG B 1 245 ? 23.95912  -0.50791  -41.77122 1.000 38.80082 ? 243 ARG B N   1 
ATOM   3842 C  CA  . ARG B 1 245 ? 24.61591  -1.37440  -40.79356 1.000 40.63474 ? 243 ARG B CA  1 
ATOM   3843 C  C   . ARG B 1 245 ? 23.76145  -1.58420  -39.54660 1.000 40.06441 ? 243 ARG B C   1 
ATOM   3844 O  O   . ARG B 1 245 ? 24.02414  -2.50963  -38.76851 1.000 35.95402 ? 243 ARG B O   1 
ATOM   3845 C  CB  . ARG B 1 245 ? 25.97281  -0.77031  -40.40786 1.000 41.85862 ? 243 ARG B CB  1 
ATOM   3846 C  CG  . ARG B 1 245 ? 26.95601  -0.66377  -41.57578 1.000 38.15405 ? 243 ARG B CG  1 
ATOM   3847 C  CD  . ARG B 1 245 ? 28.38885  -0.33475  -41.13543 1.000 43.05219 ? 243 ARG B CD  1 
ATOM   3848 N  NE  . ARG B 1 245 ? 28.43751  0.83361   -40.26512 1.000 46.10431 ? 243 ARG B NE  1 
ATOM   3849 C  CZ  . ARG B 1 245 ? 28.49815  2.09749   -40.66860 1.000 45.25745 ? 243 ARG B CZ  1 
ATOM   3850 N  NH1 . ARG B 1 245 ? 28.62159  2.41799   -41.95062 1.000 48.20844 ? 243 ARG B NH1 1 
ATOM   3851 N  NH2 . ARG B 1 245 ? 28.44048  3.06835   -39.76272 1.000 39.55158 ? 243 ARG B NH2 1 
ATOM   3852 N  N   . SER B 1 246 ? 22.74758  -0.73875  -39.35050 1.000 35.81550 ? 244 SER B N   1 
ATOM   3853 C  CA  . SER B 1 246 ? 21.92318  -0.78096  -38.15103 1.000 34.61772 ? 244 SER B CA  1 
ATOM   3854 C  C   . SER B 1 246 ? 21.06223  -2.02804  -38.08146 1.000 38.32577 ? 244 SER B C   1 
ATOM   3855 O  O   . SER B 1 246 ? 20.55383  -2.35200  -37.00502 1.000 42.46070 ? 244 SER B O   1 
ATOM   3856 C  CB  . SER B 1 246 ? 21.04594  0.48473   -38.07221 1.000 37.37728 ? 244 SER B CB  1 
ATOM   3857 O  OG  . SER B 1 246 ? 19.83019  0.35861   -38.80393 1.000 39.29004 ? 244 SER B OG  1 
ATOM   3858 N  N   . GLN B 1 247 ? 20.90557  -2.75187  -39.18068 1.000 38.30648 ? 245 GLN B N   1 
ATOM   3859 C  CA  . GLN B 1 247 ? 20.08863  -3.95317  -39.16391 1.000 42.08194 ? 245 GLN B CA  1 
ATOM   3860 C  C   . GLN B 1 247 ? 20.93056  -5.22548  -39.17075 1.000 36.78564 ? 245 GLN B C   1 
ATOM   3861 O  O   . GLN B 1 247 ? 20.38651  -6.31475  -39.38682 1.000 39.24015 ? 245 GLN B O   1 
ATOM   3862 C  CB  . GLN B 1 247 ? 19.11444  -3.91530  -40.34221 1.000 45.05691 ? 245 GLN B CB  1 
ATOM   3863 C  CG  . GLN B 1 247 ? 18.07663  -2.76484  -40.20312 1.000 45.35097 ? 245 GLN B CG  1 
ATOM   3864 C  CD  . GLN B 1 247 ? 17.29491  -2.50701  -41.49192 1.000 47.24956 ? 245 GLN B CD  1 
ATOM   3865 O  OE1 . GLN B 1 247 ? 17.83751  -2.62394  -42.59804 1.000 50.56074 ? 245 GLN B OE1 1 
ATOM   3866 N  NE2 . GLN B 1 247 ? 16.02157  -2.14332  -41.35185 1.000 45.81883 ? 245 GLN B NE2 1 
ATOM   3867 N  N   . LEU B 1 248 ? 22.24602  -5.11046  -38.93695 1.000 35.92064 ? 246 LEU B N   1 
ATOM   3868 C  CA  . LEU B 1 248 ? 23.12417  -6.27382  -38.83710 1.000 34.97398 ? 246 LEU B CA  1 
ATOM   3869 C  C   . LEU B 1 248 ? 23.00189  -6.90366  -37.45164 1.000 37.57934 ? 246 LEU B C   1 
ATOM   3870 O  O   . LEU B 1 248 ? 23.26311  -6.24830  -36.44212 1.000 34.78925 ? 246 LEU B O   1 
ATOM   3871 C  CB  . LEU B 1 248 ? 24.57093  -5.88375  -39.10646 1.000 35.16539 ? 246 LEU B CB  1 
ATOM   3872 C  CG  . LEU B 1 248 ? 24.83461  -5.46753  -40.55622 1.000 39.38263 ? 246 LEU B CG  1 
ATOM   3873 C  CD1 . LEU B 1 248 ? 26.29015  -5.06431  -40.75397 1.000 37.75783 ? 246 LEU B CD1 1 
ATOM   3874 C  CD2 . LEU B 1 248 ? 24.45103  -6.60449  -41.49563 1.000 39.04958 ? 246 LEU B CD2 1 
ATOM   3875 N  N   . ALA B 1 249 ? 22.63295  -8.17498  -37.40147 1.000 33.20078 ? 247 ALA B N   1 
ATOM   3876 C  CA  . ALA B 1 249 ? 22.46375  -8.83540  -36.10938 1.000 35.35443 ? 247 ALA B CA  1 
ATOM   3877 C  C   . ALA B 1 249 ? 23.78134  -9.46725  -35.64561 1.000 34.04412 ? 247 ALA B C   1 
ATOM   3878 O  O   . ALA B 1 249 ? 24.71622  -9.62930  -36.42198 1.000 33.26078 ? 247 ALA B O   1 
ATOM   3879 C  CB  . ALA B 1 249 ? 21.37229  -9.89545  -36.20812 1.000 34.86412 ? 247 ALA B CB  1 
ATOM   3880 N  N   . LEU B 1 250 ? 23.85611  -9.76588  -34.34340 1.000 35.48206 ? 248 LEU B N   1 
ATOM   3881 C  CA  . LEU B 1 250 ? 24.93397  -10.60587 -33.80710 1.000 33.89746 ? 248 LEU B CA  1 
ATOM   3882 C  C   . LEU B 1 250 ? 24.85872  -12.03435 -34.33186 1.000 36.75271 ? 248 LEU B C   1 
ATOM   3883 O  O   . LEU B 1 250 ? 25.89396  -12.66517 -34.57340 1.000 34.78961 ? 248 LEU B O   1 
ATOM   3884 C  CB  . LEU B 1 250 ? 24.88255  -10.65008 -32.27235 1.000 33.38560 ? 248 LEU B CB  1 
ATOM   3885 C  CG  . LEU B 1 250 ? 25.19599  -9.37909  -31.45773 1.000 34.47656 ? 248 LEU B CG  1 
ATOM   3886 C  CD1 . LEU B 1 250 ? 25.21746  -9.70591  -29.95969 1.000 33.71875 ? 248 LEU B CD1 1 
ATOM   3887 C  CD2 . LEU B 1 250 ? 26.50349  -8.74026  -31.88852 1.000 35.17056 ? 248 LEU B CD2 1 
ATOM   3888 N  N   . PHE B 1 251 ? 23.64917  -12.59518 -34.42171 1.000 33.64796 ? 249 PHE B N   1 
ATOM   3889 C  CA  . PHE B 1 251 ? 23.43885  -14.00608 -34.71571 1.000 31.56659 ? 249 PHE B CA  1 
ATOM   3890 C  C   . PHE B 1 251 ? 22.42542  -14.13759 -35.83817 1.000 33.22182 ? 249 PHE B C   1 
ATOM   3891 O  O   . PHE B 1 251 ? 21.29832  -14.58416 -35.61565 1.000 27.92415 ? 249 PHE B O   1 
ATOM   3892 C  CB  . PHE B 1 251 ? 22.95950  -14.77014 -33.47740 1.000 32.14889 ? 249 PHE B CB  1 
ATOM   3893 C  CG  . PHE B 1 251 ? 23.72314  -14.45304 -32.21572 1.000 32.47794 ? 249 PHE B CG  1 
ATOM   3894 C  CD1 . PHE B 1 251 ? 25.09598  -14.67342 -32.14728 1.000 33.28202 ? 249 PHE B CD1 1 
ATOM   3895 C  CD2 . PHE B 1 251 ? 23.05458  -13.98878 -31.07219 1.000 32.66813 ? 249 PHE B CD2 1 
ATOM   3896 C  CE1 . PHE B 1 251 ? 25.80199  -14.39539 -30.98050 1.000 35.31293 ? 249 PHE B CE1 1 
ATOM   3897 C  CE2 . PHE B 1 251 ? 23.74322  -13.72013 -29.89367 1.000 32.65694 ? 249 PHE B CE2 1 
ATOM   3898 C  CZ  . PHE B 1 251 ? 25.12117  -13.91308 -29.84560 1.000 33.94266 ? 249 PHE B CZ  1 
ATOM   3899 N  N   . PRO B 1 252 ? 22.80648  -13.78558 -37.07623 1.000 33.23083 ? 250 PRO B N   1 
ATOM   3900 C  CA  . PRO B 1 252 ? 21.85011  -13.89569 -38.19077 1.000 32.22832 ? 250 PRO B CA  1 
ATOM   3901 C  C   . PRO B 1 252 ? 21.17713  -15.26096 -38.27583 1.000 34.66944 ? 250 PRO B C   1 
ATOM   3902 O  O   . PRO B 1 252 ? 19.97656  -15.34234 -38.57092 1.000 36.31462 ? 250 PRO B O   1 
ATOM   3903 C  CB  . PRO B 1 252 ? 22.71067  -13.60327 -39.43712 1.000 37.39971 ? 250 PRO B CB  1 
ATOM   3904 C  CG  . PRO B 1 252 ? 24.11998  -13.42914 -38.95576 1.000 39.01544 ? 250 PRO B CG  1 
ATOM   3905 C  CD  . PRO B 1 252 ? 24.07496  -13.17583 -37.47573 1.000 32.53192 ? 250 PRO B CD  1 
ATOM   3906 N  N   . GLU B 1 253 ? 21.91054  -16.32960 -37.95722 1.000 30.95283 ? 251 GLU B N   1 
ATOM   3907 C  CA  . GLU B 1 253 ? 21.38305  -17.69158 -38.02602 1.000 35.41849 ? 251 GLU B CA  1 
ATOM   3908 C  C   . GLU B 1 253 ? 20.11169  -17.86430 -37.19920 1.000 35.45958 ? 251 GLU B C   1 
ATOM   3909 O  O   . GLU B 1 253 ? 19.19665  -18.60065 -37.59845 1.000 29.22811 ? 251 GLU B O   1 
ATOM   3910 C  CB  . GLU B 1 253 ? 22.47975  -18.62752 -37.53241 1.000 37.80532 ? 251 GLU B CB  1 
ATOM   3911 C  CG  . GLU B 1 253 ? 23.66061  -18.59540 -38.44747 1.000 42.55506 ? 251 GLU B CG  1 
ATOM   3912 C  CD  . GLU B 1 253 ? 24.76788  -17.68561 -37.91920 1.000 46.78414 ? 251 GLU B CD  1 
ATOM   3913 O  OE1 . GLU B 1 253 ? 24.50819  -16.82721 -37.00709 1.000 38.87094 ? 251 GLU B OE1 1 
ATOM   3914 O  OE2 . GLU B 1 253 ? 25.90207  -17.83297 -38.43552 1.000 47.82441 ? 251 GLU B OE2 1 
ATOM   3915 N  N   . LEU B 1 254 ? 20.04858  -17.21719 -36.02602 1.000 32.63360 ? 252 LEU B N   1 
ATOM   3916 C  CA  . LEU B 1 254 ? 18.83893  -17.26586 -35.20697 1.000 30.68170 ? 252 LEU B CA  1 
ATOM   3917 C  C   . LEU B 1 254 ? 17.65547  -16.63885 -35.93275 1.000 32.18724 ? 252 LEU B C   1 
ATOM   3918 O  O   . LEU B 1 254 ? 16.53253  -17.14635 -35.86481 1.000 31.45903 ? 252 LEU B O   1 
ATOM   3919 C  CB  . LEU B 1 254 ? 19.06576  -16.50623 -33.89089 1.000 35.32633 ? 252 LEU B CB  1 
ATOM   3920 C  CG  . LEU B 1 254 ? 19.62792  -17.26168 -32.70980 1.000 38.61748 ? 252 LEU B CG  1 
ATOM   3921 C  CD1 . LEU B 1 254 ? 19.44704  -16.43457 -31.43858 1.000 37.10266 ? 252 LEU B CD1 1 
ATOM   3922 C  CD2 . LEU B 1 254 ? 18.88334  -18.53665 -32.64817 1.000 36.49919 ? 252 LEU B CD2 1 
ATOM   3923 N  N   . TRP B 1 255 ? 17.87655  -15.47530 -36.56639 1.000 31.24435 ? 253 TRP B N   1 
ATOM   3924 C  CA  . TRP B 1 255 ? 16.78963  -14.82115 -37.28850 1.000 30.32918 ? 253 TRP B CA  1 
ATOM   3925 C  C   . TRP B 1 255 ? 16.40814  -15.61067 -38.52440 1.000 32.20769 ? 253 TRP B C   1 
ATOM   3926 O  O   . TRP B 1 255 ? 15.22469  -15.67179 -38.87881 1.000 30.96372 ? 253 TRP B O   1 
ATOM   3927 C  CB  . TRP B 1 255 ? 17.18121  -13.37858 -37.64214 1.000 29.37540 ? 253 TRP B CB  1 
ATOM   3928 C  CG  . TRP B 1 255 ? 17.56420  -12.63015 -36.39698 1.000 32.43903 ? 253 TRP B CG  1 
ATOM   3929 C  CD1 . TRP B 1 255 ? 18.81384  -12.53666 -35.86015 1.000 31.89153 ? 253 TRP B CD1 1 
ATOM   3930 C  CD2 . TRP B 1 255 ? 16.68355  -11.93090 -35.48938 1.000 32.13657 ? 253 TRP B CD2 1 
ATOM   3931 N  NE1 . TRP B 1 255 ? 18.77288  -11.81888 -34.69068 1.000 32.18876 ? 253 TRP B NE1 1 
ATOM   3932 C  CE2 . TRP B 1 255 ? 17.48365  -11.41451 -34.45113 1.000 30.85012 ? 253 TRP B CE2 1 
ATOM   3933 C  CE3 . TRP B 1 255 ? 15.30896  -11.67991 -35.46655 1.000 32.32481 ? 253 TRP B CE3 1 
ATOM   3934 C  CZ2 . TRP B 1 255 ? 16.95170  -10.69733 -33.38060 1.000 30.81809 ? 253 TRP B CZ2 1 
ATOM   3935 C  CZ3 . TRP B 1 255 ? 14.77100  -10.95317 -34.39472 1.000 30.96595 ? 253 TRP B CZ3 1 
ATOM   3936 C  CH2 . TRP B 1 255 ? 15.59354  -10.45937 -33.37911 1.000 33.07945 ? 253 TRP B CH2 1 
ATOM   3937 N  N   . ARG B 1 256 ? 17.39295  -16.24700 -39.16820 1.000 33.12377 ? 254 ARG B N   1 
ATOM   3938 C  CA  . ARG B 1 256 ? 17.08171  -17.16771 -40.25721 1.000 32.36681 ? 254 ARG B CA  1 
ATOM   3939 C  C   . ARG B 1 256 ? 16.21776  -18.32903 -39.77043 1.000 31.69451 ? 254 ARG B C   1 
ATOM   3940 O  O   . ARG B 1 256 ? 15.26833  -18.74165 -40.45533 1.000 33.22677 ? 254 ARG B O   1 
ATOM   3941 C  CB  . ARG B 1 256 ? 18.38586  -17.66105 -40.90165 1.000 39.00810 ? 254 ARG B CB  1 
ATOM   3942 C  CG  . ARG B 1 256 ? 18.28344  -17.97987 -42.40190 1.000 44.94873 ? 254 ARG B CG  1 
ATOM   3943 C  CD  . ARG B 1 256 ? 19.48001  -17.42026 -43.18634 1.000 49.19001 ? 254 ARG B CD  1 
ATOM   3944 N  NE  . ARG B 1 256 ? 20.74610  -17.64837 -42.49594 1.000 49.04345 ? 254 ARG B NE  1 
ATOM   3945 C  CZ  . ARG B 1 256 ? 21.76684  -16.79984 -42.48653 1.000 48.55018 ? 254 ARG B CZ  1 
ATOM   3946 N  NH1 . ARG B 1 256 ? 21.72760  -15.65726 -43.15630 1.000 45.59251 ? 254 ARG B NH1 1 
ATOM   3947 N  NH2 . ARG B 1 256 ? 22.85092  -17.09803 -41.77087 1.000 53.58859 ? 254 ARG B NH2 1 
ATOM   3948 N  N   . ALA B 1 257 ? 16.51658  -18.87346 -38.58536 1.000 32.68514 ? 255 ALA B N   1 
ATOM   3949 C  CA  . ALA B 1 257 ? 15.70611  -19.98456 -38.08315 1.000 31.53646 ? 255 ALA B CA  1 
ATOM   3950 C  C   . ALA B 1 257 ? 14.27251  -19.54237 -37.78779 1.000 28.52043 ? 255 ALA B C   1 
ATOM   3951 O  O   . ALA B 1 257 ? 13.31979  -20.31783 -37.97519 1.000 29.94256 ? 255 ALA B O   1 
ATOM   3952 C  CB  . ALA B 1 257 ? 16.35350  -20.60541 -36.83560 1.000 28.09286 ? 255 ALA B CB  1 
ATOM   3953 N  N   . ALA B 1 258 ? 14.09748  -18.31067 -37.30134 1.000 28.20089 ? 256 ALA B N   1 
ATOM   3954 C  CA  . ALA B 1 258 ? 12.75334  -17.75983 -37.12269 1.000 29.96879 ? 256 ALA B CA  1 
ATOM   3955 C  C   . ALA B 1 258 ? 11.99325  -17.72856 -38.43816 1.000 30.32047 ? 256 ALA B C   1 
ATOM   3956 O  O   . ALA B 1 258 ? 10.83166  -18.14088 -38.51310 1.000 28.37705 ? 256 ALA B O   1 
ATOM   3957 C  CB  . ALA B 1 258 ? 12.82482  -16.32678 -36.54412 1.000 26.81248 ? 256 ALA B CB  1 
ATOM   3958 N  N   . GLU B 1 259 ? 12.60162  -17.15022 -39.47349 1.000 29.68957 ? 257 GLU B N   1 
ATOM   3959 C  CA  . GLU B 1 259 ? 11.89880  -17.10264 -40.74705 1.000 32.95766 ? 257 GLU B CA  1 
ATOM   3960 C  C   . GLU B 1 259 ? 11.63271  -18.51120 -41.26352 1.000 30.49648 ? 257 GLU B C   1 
ATOM   3961 O  O   . GLU B 1 259 ? 10.56776  -18.79116 -41.82611 1.000 30.88907 ? 257 GLU B O   1 
ATOM   3962 C  CB  . GLU B 1 259 ? 12.68258  -16.24512 -41.76151 1.000 32.49623 ? 257 GLU B CB  1 
ATOM   3963 C  CG  . GLU B 1 259 ? 12.01846  -16.28613 -43.11706 1.000 34.51079 ? 257 GLU B CG  1 
ATOM   3964 C  CD  . GLU B 1 259 ? 12.48776  -15.24453 -44.10600 1.000 38.48269 ? 257 GLU B CD  1 
ATOM   3965 O  OE1 . GLU B 1 259 ? 13.02759  -14.17134 -43.70651 1.000 37.05566 ? 257 GLU B OE1 1 
ATOM   3966 O  OE2 . GLU B 1 259 ? 12.28215  -15.51498 -45.30476 1.000 38.77978 ? 257 GLU B OE2 1 
ATOM   3967 N  N   . ASP B 1 260 ? 12.58019  -19.42178 -41.02713 1.000 29.14014 ? 258 ASP B N   1 
ATOM   3968 C  CA  . ASP B 1 260 ? 12.42131  -20.82808 -41.35814 1.000 32.16748 ? 258 ASP B CA  1 
ATOM   3969 C  C   . ASP B 1 260 ? 11.15289  -21.40362 -40.72611 1.000 32.40037 ? 258 ASP B C   1 
ATOM   3970 O  O   . ASP B 1 260 ? 10.41189  -22.17974 -41.35578 1.000 27.66326 ? 258 ASP B O   1 
ATOM   3971 C  CB  . ASP B 1 260 ? 13.63631  -21.57117 -40.81430 1.000 34.60826 ? 258 ASP B CB  1 
ATOM   3972 C  CG  . ASP B 1 260 ? 14.22947  -22.49764 -41.79826 1.000 38.00331 ? 258 ASP B CG  1 
ATOM   3973 O  OD1 . ASP B 1 260 ? 14.01514  -22.26667 -42.99856 1.000 40.28060 ? 258 ASP B OD1 1 
ATOM   3974 O  OD2 . ASP B 1 260 ? 14.94762  -23.42158 -41.37978 1.000 40.88553 ? 258 ASP B OD2 1 
ATOM   3975 N  N   . ALA B 1 261 ? 10.90393  -21.05735 -39.45427 1.000 28.93430 ? 259 ALA B N   1 
ATOM   3976 C  CA  . ALA B 1 261 ? 9.71512   -21.55422 -38.77312 1.000 29.90392 ? 259 ALA B CA  1 
ATOM   3977 C  C   . ALA B 1 261 ? 8.44578   -21.02863 -39.43645 1.000 30.34174 ? 259 ALA B C   1 
ATOM   3978 O  O   . ALA B 1 261 ? 7.48211   -21.78004 -39.62992 1.000 30.85248 ? 259 ALA B O   1 
ATOM   3979 C  CB  . ALA B 1 261 ? 9.76027   -21.15598 -37.29630 1.000 31.76092 ? 259 ALA B CB  1 
ATOM   3980 N  N   . TYR B 1 262 ? 8.44759   -19.75664 -39.83697 1.000 30.29593 ? 260 TYR B N   1 
ATOM   3981 C  CA  . TYR B 1 262 ? 7.30092   -19.20031 -40.55273 1.000 30.52548 ? 260 TYR B CA  1 
ATOM   3982 C  C   . TYR B 1 262 ? 6.98933   -20.01141 -41.80831 1.000 31.25316 ? 260 TYR B C   1 
ATOM   3983 O  O   . TYR B 1 262 ? 5.83364   -20.37582 -42.06259 1.000 30.49651 ? 260 TYR B O   1 
ATOM   3984 C  CB  . TYR B 1 262 ? 7.58193   -17.75683 -40.93375 1.000 31.94779 ? 260 TYR B CB  1 
ATOM   3985 C  CG  . TYR B 1 262 ? 6.58758   -17.18985 -41.90608 1.000 31.19902 ? 260 TYR B CG  1 
ATOM   3986 C  CD1 . TYR B 1 262 ? 5.39201   -16.66017 -41.44998 1.000 30.59792 ? 260 TYR B CD1 1 
ATOM   3987 C  CD2 . TYR B 1 262 ? 6.83311   -17.19812 -43.28515 1.000 33.19227 ? 260 TYR B CD2 1 
ATOM   3988 C  CE1 . TYR B 1 262 ? 4.47780   -16.12525 -42.31370 1.000 35.22551 ? 260 TYR B CE1 1 
ATOM   3989 C  CE2 . TYR B 1 262 ? 5.90363   -16.68169 -44.17255 1.000 34.18036 ? 260 TYR B CE2 1 
ATOM   3990 C  CZ  . TYR B 1 262 ? 4.72541   -16.14044 -43.67598 1.000 35.50674 ? 260 TYR B CZ  1 
ATOM   3991 O  OH  . TYR B 1 262 ? 3.78153   -15.59878 -44.51045 1.000 34.50324 ? 260 TYR B OH  1 
ATOM   3992 N  N   . TRP B 1 263 ? 8.00631   -20.27130 -42.62296 1.000 29.70016 ? 261 TRP B N   1 
ATOM   3993 C  CA  . TRP B 1 263 ? 7.75529   -20.98613 -43.86705 1.000 32.10295 ? 261 TRP B CA  1 
ATOM   3994 C  C   . TRP B 1 263 ? 7.31606   -22.41784 -43.60572 1.000 30.12973 ? 261 TRP B C   1 
ATOM   3995 O  O   . TRP B 1 263 ? 6.43411   -22.92150 -44.29857 1.000 34.17548 ? 261 TRP B O   1 
ATOM   3996 C  CB  . TRP B 1 263 ? 8.98772   -20.96265 -44.76369 1.000 29.52838 ? 261 TRP B CB  1 
ATOM   3997 C  CG  . TRP B 1 263 ? 9.26512   -19.56899 -45.30163 1.000 33.61668 ? 261 TRP B CG  1 
ATOM   3998 C  CD1 . TRP B 1 263 ? 10.33979  -18.78701 -45.01547 1.000 27.85320 ? 261 TRP B CD1 1 
ATOM   3999 C  CD2 . TRP B 1 263 ? 8.43041   -18.80176 -46.19275 1.000 29.94699 ? 261 TRP B CD2 1 
ATOM   4000 N  NE1 . TRP B 1 263 ? 10.22189  -17.58669 -45.66485 1.000 34.95808 ? 261 TRP B NE1 1 
ATOM   4001 C  CE2 . TRP B 1 263 ? 9.05856   -17.57222 -46.39012 1.000 33.07741 ? 261 TRP B CE2 1 
ATOM   4002 C  CE3 . TRP B 1 263 ? 7.20596   -19.04523 -46.82628 1.000 34.21823 ? 261 TRP B CE3 1 
ATOM   4003 C  CZ2 . TRP B 1 263 ? 8.53473   -16.57943 -47.24802 1.000 36.36628 ? 261 TRP B CZ2 1 
ATOM   4004 C  CZ3 . TRP B 1 263 ? 6.67726   -18.06380 -47.66198 1.000 35.86136 ? 261 TRP B CZ3 1 
ATOM   4005 C  CH2 . TRP B 1 263 ? 7.33915   -16.84639 -47.86146 1.000 34.66440 ? 261 TRP B CH2 1 
ATOM   4006 N  N   . LEU B 1 264 ? 7.88709   -23.07783 -42.59589 1.000 29.83593 ? 262 LEU B N   1 
ATOM   4007 C  CA  . LEU B 1 264 ? 7.61664   -24.51120 -42.42793 1.000 29.70266 ? 262 LEU B CA  1 
ATOM   4008 C  C   . LEU B 1 264 ? 6.30564   -24.74754 -41.69672 1.000 33.98216 ? 262 LEU B C   1 
ATOM   4009 O  O   . LEU B 1 264 ? 5.57983   -25.69124 -42.01915 1.000 32.39206 ? 262 LEU B O   1 
ATOM   4010 C  CB  . LEU B 1 264 ? 8.75103   -25.19171 -41.66766 1.000 26.04679 ? 262 LEU B CB  1 
ATOM   4011 C  CG  . LEU B 1 264 ? 10.11627  -25.20436 -42.35499 1.000 32.99926 ? 262 LEU B CG  1 
ATOM   4012 C  CD1 . LEU B 1 264 ? 11.20081  -25.38228 -41.32054 1.000 28.28758 ? 262 LEU B CD1 1 
ATOM   4013 C  CD2 . LEU B 1 264 ? 10.16907  -26.33037 -43.43018 1.000 30.30133 ? 262 LEU B CD2 1 
ATOM   4014 N  N   . LEU B 1 265 ? 5.97883   -23.89097 -40.71551 1.000 31.09326 ? 263 LEU B N   1 
ATOM   4015 C  CA  . LEU B 1 265 ? 4.83260   -24.11621 -39.85122 1.000 32.46089 ? 263 LEU B CA  1 
ATOM   4016 C  C   . LEU B 1 265 ? 3.65280   -23.18958 -40.10857 1.000 36.82646 ? 263 LEU B C   1 
ATOM   4017 O  O   . LEU B 1 265 ? 2.53009   -23.52821 -39.71198 1.000 34.76587 ? 263 LEU B O   1 
ATOM   4018 C  CB  . LEU B 1 265 ? 5.24758   -23.99049 -38.38180 1.000 33.69996 ? 263 LEU B CB  1 
ATOM   4019 C  CG  . LEU B 1 265 ? 6.48440   -24.78879 -37.95709 1.000 32.73222 ? 263 LEU B CG  1 
ATOM   4020 C  CD1 . LEU B 1 265 ? 6.89883   -24.33901 -36.57054 1.000 35.49698 ? 263 LEU B CD1 1 
ATOM   4021 C  CD2 . LEU B 1 265 ? 6.19847   -26.28293 -37.96469 1.000 35.95246 ? 263 LEU B CD2 1 
ATOM   4022 N  N   . GLY B 1 266 ? 3.86874   -22.03665 -40.73703 1.000 33.30189 ? 264 GLY B N   1 
ATOM   4023 C  CA  . GLY B 1 266 ? 2.74944   -21.18693 -41.10389 1.000 34.07756 ? 264 GLY B CA  1 
ATOM   4024 C  C   . GLY B 1 266 ? 1.95011   -21.85417 -42.20497 1.000 39.70217 ? 264 GLY B C   1 
ATOM   4025 O  O   . GLY B 1 266 ? 2.50759   -22.47947 -43.10802 1.000 36.27422 ? 264 GLY B O   1 
ATOM   4026 N  N   . THR B 1 267 ? 0.62355   -21.77745 -42.10138 1.000 37.91277 ? 265 THR B N   1 
ATOM   4027 C  CA  . THR B 1 267 ? -0.22728  -22.47507 -43.06419 1.000 42.85563 ? 265 THR B CA  1 
ATOM   4028 C  C   . THR B 1 267 ? -1.12577  -21.49382 -43.80703 1.000 41.82826 ? 265 THR B C   1 
ATOM   4029 O  O   . THR B 1 267 ? -2.19356  -21.86824 -44.30278 1.000 42.48692 ? 265 THR B O   1 
ATOM   4030 C  CB  . THR B 1 267 ? -1.05230  -23.57273 -42.39018 1.000 38.90163 ? 265 THR B CB  1 
ATOM   4031 O  OG1 . THR B 1 267 ? -1.95766  -22.98863 -41.45378 1.000 41.60631 ? 265 THR B OG1 1 
ATOM   4032 C  CG2 . THR B 1 267 ? -0.14433  -24.57074 -41.65063 1.000 38.62109 ? 265 THR B CG2 1 
ATOM   4033 N  N   . ARG B 1 268 ? -0.64774  -20.24919 -43.93639 1.000 41.43427 ? 266 ARG B N   1 
ATOM   4034 C  CA  . ARG B 1 268 ? -1.42243  -19.10353 -44.38706 1.000 42.68392 ? 266 ARG B CA  1 
ATOM   4035 C  C   . ARG B 1 268 ? -0.84719  -18.37565 -45.58649 1.000 45.98065 ? 266 ARG B C   1 
ATOM   4036 O  O   . ARG B 1 268 ? -1.54049  -17.51219 -46.14686 1.000 47.33767 ? 266 ARG B O   1 
ATOM   4037 C  CB  . ARG B 1 268 ? -1.49240  -18.04617 -43.27965 1.000 44.33993 ? 266 ARG B CB  1 
ATOM   4038 C  CG  . ARG B 1 268 ? -2.39468  -18.30500 -42.18420 1.000 43.75214 ? 266 ARG B CG  1 
ATOM   4039 C  CD  . ARG B 1 268 ? -3.22142  -17.09626 -42.04270 1.000 40.50136 ? 266 ARG B CD  1 
ATOM   4040 N  NE  . ARG B 1 268 ? -4.03691  -17.24943 -40.86881 1.000 45.36900 ? 266 ARG B NE  1 
ATOM   4041 C  CZ  . ARG B 1 268 ? -5.26730  -16.80128 -40.76277 1.000 42.89032 ? 266 ARG B CZ  1 
ATOM   4042 N  NH1 . ARG B 1 268 ? -5.85896  -16.15099 -41.75515 1.000 43.55910 ? 266 ARG B NH1 1 
ATOM   4043 N  NH2 . ARG B 1 268 ? -5.91463  -17.00536 -39.63427 1.000 45.54032 ? 266 ARG B NH2 1 
ATOM   4044 N  N   . HIS B 1 269 ? 0.42556   -18.57820 -45.90791 1.000 45.37916 ? 267 HIS B N   1 
ATOM   4045 C  CA  . HIS B 1 269 ? 1.07869   -17.70374 -46.87977 1.000 46.72790 ? 267 HIS B CA  1 
ATOM   4046 C  C   . HIS B 1 269 ? 0.32798   -17.73073 -48.20507 1.000 47.27887 ? 267 HIS B C   1 
ATOM   4047 O  O   . HIS B 1 269 ? -0.14293  -18.78688 -48.64607 1.000 46.88652 ? 267 HIS B O   1 
ATOM   4048 C  CB  . HIS B 1 269 ? 2.53352   -18.13275 -47.09232 1.000 42.37789 ? 267 HIS B CB  1 
ATOM   4049 C  CG  . HIS B 1 269 ? 3.36714   -17.09950 -47.77164 1.000 45.36914 ? 267 HIS B CG  1 
ATOM   4050 N  ND1 . HIS B 1 269 ? 3.83719   -15.98294 -47.11355 1.000 38.82211 ? 267 HIS B ND1 1 
ATOM   4051 C  CD2 . HIS B 1 269 ? 3.82064   -17.00891 -49.04811 1.000 43.71192 ? 267 HIS B CD2 1 
ATOM   4052 C  CE1 . HIS B 1 269 ? 4.53994   -15.24633 -47.95460 1.000 42.63398 ? 267 HIS B CE1 1 
ATOM   4053 N  NE2 . HIS B 1 269 ? 4.55527   -15.85123 -49.13147 1.000 42.86669 ? 267 HIS B NE2 1 
ATOM   4054 N  N   . ASP B 1 270 ? 0.20182   -16.55068 -48.81895 1.000 47.11939 ? 268 ASP B N   1 
ATOM   4055 C  CA  . ASP B 1 270 ? -0.44552  -16.35546 -50.12576 1.000 49.40706 ? 268 ASP B CA  1 
ATOM   4056 C  C   . ASP B 1 270 ? -1.93008  -16.73410 -50.11006 1.000 52.34487 ? 268 ASP B C   1 
ATOM   4057 O  O   . ASP B 1 270 ? -2.48877  -17.12899 -51.13845 1.000 52.15429 ? 268 ASP B O   1 
ATOM   4058 C  CB  . ASP B 1 270 ? 0.27906   -17.12768 -51.23823 1.000 47.10695 ? 268 ASP B CB  1 
ATOM   4059 C  CG  . ASP B 1 270 ? 1.42518   -16.34311 -51.85004 1.000 54.85871 ? 268 ASP B CG  1 
ATOM   4060 O  OD1 . ASP B 1 270 ? 1.34184   -15.09374 -51.92524 1.000 50.90580 ? 268 ASP B OD1 1 
ATOM   4061 O  OD2 . ASP B 1 270 ? 2.41245   -16.98517 -52.27675 1.000 57.09005 ? 268 ASP B OD2 1 
ATOM   4062 N  N   . THR B 1 271 ? -2.59039  -16.63598 -48.95102 1.000 49.26662 ? 269 THR B N   1 
ATOM   4063 C  CA  . THR B 1 271 ? -4.02073  -16.91366 -48.86030 1.000 51.55302 ? 269 THR B CA  1 
ATOM   4064 C  C   . THR B 1 271 ? -4.85669  -15.76515 -48.29431 1.000 54.51476 ? 269 THR B C   1 
ATOM   4065 O  O   . THR B 1 271 ? -6.09024  -15.82095 -48.38916 1.000 56.01549 ? 269 THR B O   1 
ATOM   4066 C  CB  . THR B 1 271 ? -4.27516  -18.16831 -48.00683 1.000 49.17637 ? 269 THR B CB  1 
ATOM   4067 O  OG1 . THR B 1 271 ? -4.11078  -17.84717 -46.62046 1.000 52.08410 ? 269 THR B OG1 1 
ATOM   4068 C  CG2 . THR B 1 271 ? -3.30544  -19.29171 -48.38692 1.000 50.46090 ? 269 THR B CG2 1 
ATOM   4069 N  N   . ASP B 1 272 ? -4.23921  -14.73716 -47.71969 1.000 49.95871 ? 270 ASP B N   1 
ATOM   4070 C  CA  . ASP B 1 272 ? -4.96784  -13.67315 -47.04675 1.000 52.28437 ? 270 ASP B CA  1 
ATOM   4071 C  C   . ASP B 1 272 ? -5.02005  -12.41404 -47.90332 1.000 53.22842 ? 270 ASP B C   1 
ATOM   4072 O  O   . ASP B 1 272 ? -4.25009  -12.23823 -48.85070 1.000 52.97232 ? 270 ASP B O   1 
ATOM   4073 C  CB  . ASP B 1 272 ? -4.34196  -13.35282 -45.68541 1.000 48.09329 ? 270 ASP B CB  1 
ATOM   4074 C  CG  . ASP B 1 272 ? -4.51729  -14.47947 -44.67970 1.000 47.76304 ? 270 ASP B CG  1 
ATOM   4075 O  OD1 . ASP B 1 272 ? -5.66537  -14.93753 -44.47052 1.000 49.99059 ? 270 ASP B OD1 1 
ATOM   4076 O  OD2 . ASP B 1 272 ? -3.50010  -14.90422 -44.09580 1.000 43.92104 ? 270 ASP B OD2 1 
ATOM   4077 N  N   . ALA B 1 273 ? -5.94502  -11.53170 -47.54061 1.000 54.36012 ? 271 ALA B N   1 
ATOM   4078 C  CA  . ALA B 1 273 ? -6.23347  -10.32853 -48.30798 1.000 54.66472 ? 271 ALA B CA  1 
ATOM   4079 C  C   . ALA B 1 273 ? -6.94099  -9.34944  -47.38178 1.000 54.30109 ? 271 ALA B C   1 
ATOM   4080 O  O   . ALA B 1 273 ? -7.37233  -9.73085  -46.28227 1.000 55.17323 ? 271 ALA B O   1 
ATOM   4081 C  CB  . ALA B 1 273 ? -7.09060  -10.65496 -49.54513 1.000 55.20768 ? 271 ALA B CB  1 
ATOM   4082 N  N   . PRO B 1 274 ? -7.05618  -8.07655  -47.77443 1.000 56.06729 ? 272 PRO B N   1 
ATOM   4083 C  CA  . PRO B 1 274 ? -7.74518  -7.10579  -46.90746 1.000 55.76563 ? 272 PRO B CA  1 
ATOM   4084 C  C   . PRO B 1 274 ? -9.25101  -7.33584  -46.85761 1.000 60.31881 ? 272 PRO B C   1 
ATOM   4085 O  O   . PRO B 1 274 ? -9.85936  -7.86637  -47.79130 1.000 62.96107 ? 272 PRO B O   1 
ATOM   4086 C  CB  . PRO B 1 274 ? -7.41413  -5.74846  -47.54601 1.000 57.58131 ? 272 PRO B CB  1 
ATOM   4087 C  CG  . PRO B 1 274 ? -6.22006  -5.99014  -48.40599 1.000 56.64624 ? 272 PRO B CG  1 
ATOM   4088 C  CD  . PRO B 1 274 ? -6.39075  -7.40917  -48.90848 1.000 58.05942 ? 272 PRO B CD  1 
ATOM   4089 N  N   . VAL B 1 275 ? -9.84788  -6.92350  -45.74080 1.000 58.77690 ? 273 VAL B N   1 
ATOM   4090 C  CA  . VAL B 1 275 ? -11.28093 -7.07184  -45.50812 1.000 58.25211 ? 273 VAL B CA  1 
ATOM   4091 C  C   . VAL B 1 275 ? -11.93142 -5.70617  -45.26023 1.000 60.81429 ? 273 VAL B C   1 
ATOM   4092 O  O   . VAL B 1 275 ? -13.12933 -5.50542  -45.49934 1.000 66.15402 ? 273 VAL B O   1 
ATOM   4093 C  CB  . VAL B 1 275 ? -11.53497 -8.00431  -44.32972 1.000 57.44167 ? 273 VAL B CB  1 
ATOM   4094 C  CG1 . VAL B 1 275 ? -11.02951 -7.35087  -43.06138 1.000 58.32789 ? 273 VAL B CG1 1 
ATOM   4095 C  CG2 . VAL B 1 275 ? -13.01099 -8.33227  -44.21371 1.000 57.71228 ? 273 VAL B CG2 1 
ATOM   4096 N  N   . LYS C 1 4   ? -18.56867 -12.61011 -4.14618  1.000 53.30543 ? 2   LYS C N   1 
ATOM   4097 C  CA  . LYS C 1 4   ? -17.67975 -12.34837 -5.27584  1.000 47.99717 ? 2   LYS C CA  1 
ATOM   4098 C  C   . LYS C 1 4   ? -17.86906 -13.32046 -6.43115  1.000 50.73094 ? 2   LYS C C   1 
ATOM   4099 O  O   . LYS C 1 4   ? -18.84352 -14.07253 -6.51577  1.000 51.27296 ? 2   LYS C O   1 
ATOM   4100 C  CB  . LYS C 1 4   ? -16.20631 -12.42932 -4.87067  1.000 43.92460 ? 2   LYS C CB  1 
ATOM   4101 C  CG  . LYS C 1 4   ? -15.76558 -13.80678 -4.35678  1.000 51.44456 ? 2   LYS C CG  1 
ATOM   4102 C  CD  . LYS C 1 4   ? -15.20375 -13.74666 -2.95854  1.000 53.28649 ? 2   LYS C CD  1 
ATOM   4103 C  CE  . LYS C 1 4   ? -14.55664 -15.06205 -2.58494  1.000 57.68350 ? 2   LYS C CE  1 
ATOM   4104 N  NZ  . LYS C 1 4   ? -14.27884 -15.12307 -1.12801  1.000 64.11067 ? 2   LYS C NZ  1 
ATOM   4105 N  N   . ARG C 1 5   ? -16.86699 -13.32361 -7.30301  1.000 51.04435 ? 3   ARG C N   1 
ATOM   4106 C  CA  . ARG C 1 5   ? -16.91501 -14.08566 -8.53516  1.000 47.43302 ? 3   ARG C CA  1 
ATOM   4107 C  C   . ARG C 1 5   ? -15.48102 -14.42198 -8.91999  1.000 43.87541 ? 3   ARG C C   1 
ATOM   4108 O  O   . ARG C 1 5   ? -14.53539 -13.76449 -8.47718  1.000 43.90278 ? 3   ARG C O   1 
ATOM   4109 C  CB  . ARG C 1 5   ? -17.68273 -13.28456 -9.60208  1.000 49.19276 ? 3   ARG C CB  1 
ATOM   4110 C  CG  . ARG C 1 5   ? -18.06235 -14.09014 -10.81302 1.000 55.10199 ? 3   ARG C CG  1 
ATOM   4111 C  CD  . ARG C 1 5   ? -18.72978 -13.24483 -11.89614 1.000 57.57936 ? 3   ARG C CD  1 
ATOM   4112 N  NE  . ARG C 1 5   ? -18.33157 -11.84305 -11.91205 1.000 54.61335 ? 3   ARG C NE  1 
ATOM   4113 C  CZ  . ARG C 1 5   ? -18.30956 -11.10298 -13.01466 1.000 56.46027 ? 3   ARG C CZ  1 
ATOM   4114 N  NH1 . ARG C 1 5   ? -18.59931 -11.62245 -14.19780 1.000 58.46455 ? 3   ARG C NH1 1 
ATOM   4115 N  NH2 . ARG C 1 5   ? -17.97721 -9.81490  -12.93103 1.000 51.14065 ? 3   ARG C NH2 1 
ATOM   4116 N  N   . SER C 1 6   ? -15.31776 -15.48236 -9.70812  1.000 44.02364 ? 4   SER C N   1 
ATOM   4117 C  CA  . SER C 1 6   ? -14.00071 -15.99332 -10.06205 1.000 44.44154 ? 4   SER C CA  1 
ATOM   4118 C  C   . SER C 1 6   ? -13.78726 -15.92203 -11.56386 1.000 44.82342 ? 4   SER C C   1 
ATOM   4119 O  O   . SER C 1 6   ? -14.68098 -16.25662 -12.34918 1.000 42.56236 ? 4   SER C O   1 
ATOM   4120 C  CB  . SER C 1 6   ? -13.80704 -17.44936 -9.60994  1.000 43.34718 ? 4   SER C CB  1 
ATOM   4121 O  OG  . SER C 1 6   ? -12.56854 -17.96187 -10.08544 1.000 41.13138 ? 4   SER C OG  1 
ATOM   4122 N  N   . LEU C 1 7   ? -12.58616 -15.50487 -11.95947 1.000 42.88489 ? 5   LEU C N   1 
ATOM   4123 C  CA  . LEU C 1 7   ? -12.24290 -15.54020 -13.37105 1.000 41.13774 ? 5   LEU C CA  1 
ATOM   4124 C  C   . LEU C 1 7   ? -11.96804 -16.96113 -13.85473 1.000 44.44827 ? 5   LEU C C   1 
ATOM   4125 O  O   . LEU C 1 7   ? -12.03723 -17.21829 -15.06273 1.000 43.11969 ? 5   LEU C O   1 
ATOM   4126 C  CB  . LEU C 1 7   ? -11.03175 -14.64262 -13.62746 1.000 45.87521 ? 5   LEU C CB  1 
ATOM   4127 C  CG  . LEU C 1 7   ? -11.29777 -13.24612 -14.18851 1.000 44.24659 ? 5   LEU C CG  1 
ATOM   4128 C  CD1 . LEU C 1 7   ? -10.03168 -12.70694 -14.81011 1.000 42.20741 ? 5   LEU C CD1 1 
ATOM   4129 C  CD2 . LEU C 1 7   ? -12.43401 -13.24950 -15.21607 1.000 43.29982 ? 5   LEU C CD2 1 
ATOM   4130 N  N   . ASN C 1 8   ? -11.67709 -17.89417 -12.94867 1.000 40.67434 ? 6   ASN C N   1 
ATOM   4131 C  CA  . ASN C 1 8   ? -11.38020 -19.27504 -13.32138 1.000 43.38114 ? 6   ASN C CA  1 
ATOM   4132 C  C   . ASN C 1 8   ? -12.21139 -20.22233 -12.46229 1.000 44.22433 ? 6   ASN C C   1 
ATOM   4133 O  O   . ASN C 1 8   ? -11.67671 -21.03152 -11.69599 1.000 43.31105 ? 6   ASN C O   1 
ATOM   4134 C  CB  . ASN C 1 8   ? -9.88575  -19.57342 -13.20251 1.000 37.69747 ? 6   ASN C CB  1 
ATOM   4135 C  CG  . ASN C 1 8   ? -9.32559  -19.23898 -11.84423 1.000 37.52970 ? 6   ASN C CG  1 
ATOM   4136 O  OD1 . ASN C 1 8   ? -9.77529  -18.29399 -11.17840 1.000 38.20202 ? 6   ASN C OD1 1 
ATOM   4137 N  ND2 . ASN C 1 8   ? -8.32810  -20.01059 -11.41714 1.000 35.42701 ? 6   ASN C ND2 1 
ATOM   4138 N  N   . PRO C 1 9   ? -13.53935 -20.16654 -12.60364 1.000 44.27163 ? 7   PRO C N   1 
ATOM   4139 C  CA  . PRO C 1 9   ? -14.41079 -20.92108 -11.69026 1.000 47.70354 ? 7   PRO C CA  1 
ATOM   4140 C  C   . PRO C 1 9   ? -14.19178 -22.41847 -11.74118 1.000 52.24036 ? 7   PRO C C   1 
ATOM   4141 O  O   . PRO C 1 9   ? -14.36695 -23.08907 -10.71417 1.000 55.84760 ? 7   PRO C O   1 
ATOM   4142 C  CB  . PRO C 1 9   ? -15.81791 -20.54890 -12.17452 1.000 47.77279 ? 7   PRO C CB  1 
ATOM   4143 C  CG  . PRO C 1 9   ? -15.63137 -20.22269 -13.61638 1.000 45.74318 ? 7   PRO C CG  1 
ATOM   4144 C  CD  . PRO C 1 9   ? -14.29949 -19.54431 -13.70157 1.000 44.35182 ? 7   PRO C CD  1 
ATOM   4145 N  N   . ASP C 1 10  ? -13.80970 -22.97401 -12.89309 1.000 50.82550 ? 8   ASP C N   1 
ATOM   4146 C  CA  . ASP C 1 10  ? -13.60287 -24.42005 -12.93768 1.000 55.42722 ? 8   ASP C CA  1 
ATOM   4147 C  C   . ASP C 1 10  ? -12.25727 -24.83513 -12.35803 1.000 57.83485 ? 8   ASP C C   1 
ATOM   4148 O  O   . ASP C 1 10  ? -11.94444 -26.03339 -12.35936 1.000 54.16229 ? 8   ASP C O   1 
ATOM   4149 C  CB  . ASP C 1 10  ? -13.74095 -24.96359 -14.37214 1.000 55.94312 ? 8   ASP C CB  1 
ATOM   4150 C  CG  . ASP C 1 10  ? -15.06991 -24.58847 -15.01089 1.000 59.81073 ? 8   ASP C CG  1 
ATOM   4151 O  OD1 . ASP C 1 10  ? -16.12170 -24.88695 -14.39866 1.000 55.67682 ? 8   ASP C OD1 1 
ATOM   4152 O  OD2 . ASP C 1 10  ? -15.06166 -23.99282 -16.11559 1.000 61.64214 ? 8   ASP C OD2 1 
ATOM   4153 N  N   . GLU C 1 11  ? -11.44898 -23.89122 -11.88590 1.000 53.83867 ? 9   GLU C N   1 
ATOM   4154 C  CA  . GLU C 1 11  ? -10.32296 -24.27394 -11.04666 1.000 49.01197 ? 9   GLU C CA  1 
ATOM   4155 C  C   . GLU C 1 11  ? -10.90527 -24.71928 -9.71224  1.000 51.84572 ? 9   GLU C C   1 
ATOM   4156 O  O   . GLU C 1 11  ? -11.64505 -23.95291 -9.08871  1.000 53.73539 ? 9   GLU C O   1 
ATOM   4157 C  CB  . GLU C 1 11  ? -9.32055  -23.12001 -10.86614 1.000 45.65114 ? 9   GLU C CB  1 
ATOM   4158 C  CG  . GLU C 1 11  ? -8.37742  -23.34144 -9.69098  1.000 42.79985 ? 9   GLU C CG  1 
ATOM   4159 C  CD  . GLU C 1 11  ? -7.46846  -24.55215 -9.91540  1.000 49.94048 ? 9   GLU C CD  1 
ATOM   4160 O  OE1 . GLU C 1 11  ? -6.87550  -24.65548 -11.00967 1.000 47.14818 ? 9   GLU C OE1 1 
ATOM   4161 O  OE2 . GLU C 1 11  ? -7.39645  -25.43588 -9.02490  1.000 47.70550 ? 9   GLU C OE2 1 
ATOM   4162 N  N   . PRO C 1 12  ? -10.66423 -25.94963 -9.26786  1.000 51.83100 ? 10  PRO C N   1 
ATOM   4163 C  CA  . PRO C 1 12  ? -11.30189 -26.41556 -8.03106  1.000 53.92463 ? 10  PRO C CA  1 
ATOM   4164 C  C   . PRO C 1 12  ? -10.53004 -26.07325 -6.76483  1.000 53.06706 ? 10  PRO C C   1 
ATOM   4165 O  O   . PRO C 1 12  ? -11.11613 -26.10719 -5.67534  1.000 49.76504 ? 10  PRO C O   1 
ATOM   4166 C  CB  . PRO C 1 12  ? -11.37036 -27.93255 -8.23235  1.000 54.41486 ? 10  PRO C CB  1 
ATOM   4167 C  CG  . PRO C 1 12  ? -10.14437 -28.22428 -9.03583  1.000 53.02590 ? 10  PRO C CG  1 
ATOM   4168 C  CD  . PRO C 1 12  ? -9.94840  -27.03400 -9.96124  1.000 50.94913 ? 10  PRO C CD  1 
ATOM   4169 N  N   . ASN C 1 13  ? -9.23140  -25.77471 -6.86544  1.000 49.89038 ? 11  ASN C N   1 
ATOM   4170 C  CA  . ASN C 1 13  ? -8.47033  -25.37915 -5.68088  1.000 43.85882 ? 11  ASN C CA  1 
ATOM   4171 C  C   . ASN C 1 13  ? -8.71240  -23.89113 -5.46798  1.000 44.72565 ? 11  ASN C C   1 
ATOM   4172 O  O   . ASN C 1 13  ? -8.26373  -23.05648 -6.27201  1.000 42.10660 ? 11  ASN C O   1 
ATOM   4173 C  CB  . ASN C 1 13  ? -6.97828  -25.66487 -5.83122  1.000 40.99218 ? 11  ASN C CB  1 
ATOM   4174 C  CG  . ASN C 1 13  ? -6.18520  -25.27759 -4.58707  1.000 39.04956 ? 11  ASN C CG  1 
ATOM   4175 O  OD1 . ASN C 1 13  ? -6.63491  -24.44754 -3.80043  1.000 41.51144 ? 11  ASN C OD1 1 
ATOM   4176 N  ND2 . ASN C 1 13  ? -4.96407  -25.78573 -4.46204  1.000 36.63871 ? 11  ASN C ND2 1 
ATOM   4177 N  N   . ALA C 1 14  ? -9.39185  -23.54864 -4.37193  1.000 38.23825 ? 12  ALA C N   1 
ATOM   4178 C  CA  . ALA C 1 14  ? -9.81139  -22.16705 -4.17030  1.000 38.86515 ? 12  ALA C CA  1 
ATOM   4179 C  C   . ALA C 1 14  ? -8.64014  -21.20859 -3.96511  1.000 32.98255 ? 12  ALA C C   1 
ATOM   4180 O  O   . ALA C 1 14  ? -8.79504  -20.01294 -4.21760  1.000 36.72661 ? 12  ALA C O   1 
ATOM   4181 C  CB  . ALA C 1 14  ? -10.77431 -22.09176 -2.98073  1.000 44.07186 ? 12  ALA C CB  1 
ATOM   4182 N  N   . LEU C 1 15  ? -7.47180  -21.69534 -3.53252  1.000 34.64598 ? 13  LEU C N   1 
ATOM   4183 C  CA  . LEU C 1 15  ? -6.31961  -20.81870 -3.33507  1.000 34.73787 ? 13  LEU C CA  1 
ATOM   4184 C  C   . LEU C 1 15  ? -5.74644  -20.32338 -4.65597  1.000 35.49205 ? 13  LEU C C   1 
ATOM   4185 O  O   . LEU C 1 15  ? -4.91087  -19.41498 -4.64848  1.000 34.44638 ? 13  LEU C O   1 
ATOM   4186 C  CB  . LEU C 1 15  ? -5.23133  -21.54882 -2.55188  1.000 35.92849 ? 13  LEU C CB  1 
ATOM   4187 C  CG  . LEU C 1 15  ? -5.66804  -22.04943 -1.15314  1.000 38.96456 ? 13  LEU C CG  1 
ATOM   4188 C  CD1 . LEU C 1 15  ? -4.50354  -22.72037 -0.43789  1.000 38.54739 ? 13  LEU C CD1 1 
ATOM   4189 C  CD2 . LEU C 1 15  ? -6.20980  -20.89137 -0.33543  1.000 35.19168 ? 13  LEU C CD2 1 
ATOM   4190 N  N   . LEU C 1 16  ? -6.16465  -20.92487 -5.76773  1.000 32.48318 ? 14  LEU C N   1 
ATOM   4191 C  CA  . LEU C 1 16  ? -5.74852  -20.55225 -7.11000  1.000 35.56896 ? 14  LEU C CA  1 
ATOM   4192 C  C   . LEU C 1 16  ? -6.86573  -19.85645 -7.88088  1.000 36.59651 ? 14  LEU C C   1 
ATOM   4193 O  O   . LEU C 1 16  ? -6.71388  -19.60298 -9.07482  1.000 35.05649 ? 14  LEU C O   1 
ATOM   4194 C  CB  . LEU C 1 16  ? -5.27395  -21.79937 -7.87483  1.000 35.32529 ? 14  LEU C CB  1 
ATOM   4195 C  CG  . LEU C 1 16  ? -4.28535  -22.76631 -7.18569  1.000 37.46939 ? 14  LEU C CG  1 
ATOM   4196 C  CD1 . LEU C 1 16  ? -3.86015  -23.92347 -8.10759  1.000 40.22196 ? 14  LEU C CD1 1 
ATOM   4197 C  CD2 . LEU C 1 16  ? -3.04924  -22.03093 -6.70866  1.000 32.56036 ? 14  LEU C CD2 1 
ATOM   4198 N  N   . SER C 1 17  ? -8.00345  -19.59479 -7.24852  1.000 35.76574 ? 15  SER C N   1 
ATOM   4199 C  CA  . SER C 1 17  ? -9.04854  -18.81695 -7.90356  1.000 38.29292 ? 15  SER C CA  1 
ATOM   4200 C  C   . SER C 1 17  ? -8.63748  -17.35223 -7.96625  1.000 36.25749 ? 15  SER C C   1 
ATOM   4201 O  O   . SER C 1 17  ? -8.13195  -16.78652 -6.99164  1.000 33.66683 ? 15  SER C O   1 
ATOM   4202 C  CB  . SER C 1 17  ? -10.37139 -18.94956 -7.15486  1.000 36.94935 ? 15  SER C CB  1 
ATOM   4203 O  OG  . SER C 1 17  ? -11.39377 -18.21026 -7.78888  1.000 38.90417 ? 15  SER C OG  1 
ATOM   4204 N  N   . TYR C 1 18  ? -8.82338  -16.74257 -9.12233  1.000 36.04079 ? 16  TYR C N   1 
ATOM   4205 C  CA  . TYR C 1 18  ? -8.66412  -15.29251 -9.21722  1.000 35.66453 ? 16  TYR C CA  1 
ATOM   4206 C  C   . TYR C 1 18  ? -10.03194 -14.70364 -8.89838  1.000 34.44382 ? 16  TYR C C   1 
ATOM   4207 O  O   . TYR C 1 18  ? -10.90937 -14.64453 -9.75884  1.000 37.73752 ? 16  TYR C O   1 
ATOM   4208 C  CB  . TYR C 1 18  ? -8.15117  -14.89771 -10.60134 1.000 32.75640 ? 16  TYR C CB  1 
ATOM   4209 C  CG  . TYR C 1 18  ? -7.83472  -13.42536 -10.68353 1.000 34.37729 ? 16  TYR C CG  1 
ATOM   4210 C  CD1 . TYR C 1 18  ? -6.57166  -12.94017 -10.35775 1.000 32.69590 ? 16  TYR C CD1 1 
ATOM   4211 C  CD2 . TYR C 1 18  ? -8.81525  -12.51492 -11.04423 1.000 32.50002 ? 16  TYR C CD2 1 
ATOM   4212 C  CE1 . TYR C 1 18  ? -6.30015  -11.55839 -10.41513 1.000 32.12565 ? 16  TYR C CE1 1 
ATOM   4213 C  CE2 . TYR C 1 18  ? -8.54912  -11.17849 -11.10787 1.000 32.32775 ? 16  TYR C CE2 1 
ATOM   4214 C  CZ  . TYR C 1 18  ? -7.29331  -10.70969 -10.80526 1.000 31.58745 ? 16  TYR C CZ  1 
ATOM   4215 O  OH  . TYR C 1 18  ? -7.06261  -9.35024  -10.87322 1.000 39.37311 ? 16  TYR C OH  1 
ATOM   4216 N  N   . ASP C 1 19  ? -10.23706 -14.32260 -7.62617  1.000 35.15896 ? 17  ASP C N   1 
ATOM   4217 C  CA  . ASP C 1 19  ? -11.49941 -13.73223 -7.17664  1.000 38.52172 ? 17  ASP C CA  1 
ATOM   4218 C  C   . ASP C 1 19  ? -11.57645 -12.24059 -7.48275  1.000 34.96957 ? 17  ASP C C   1 
ATOM   4219 O  O   . ASP C 1 19  ? -10.60385 -11.50236 -7.30466  1.000 34.02543 ? 17  ASP C O   1 
ATOM   4220 C  CB  . ASP C 1 19  ? -11.68816 -13.91943 -5.66830  1.000 39.93418 ? 17  ASP C CB  1 
ATOM   4221 C  CG  . ASP C 1 19  ? -11.76486 -15.38791 -5.27054  1.000 44.71780 ? 17  ASP C CG  1 
ATOM   4222 O  OD1 . ASP C 1 19  ? -12.29152 -16.19176 -6.07643  1.000 40.22179 ? 17  ASP C OD1 1 
ATOM   4223 O  OD2 . ASP C 1 19  ? -11.30333 -15.72898 -4.15809  1.000 45.64408 ? 17  ASP C OD2 1 
ATOM   4224 N  N   . PHE C 1 20  ? -12.74804 -11.79178 -7.91565  1.000 33.39274 ? 18  PHE C N   1 
ATOM   4225 C  CA  . PHE C 1 20  ? -12.92854 -10.38182 -8.23864  1.000 35.56712 ? 18  PHE C CA  1 
ATOM   4226 C  C   . PHE C 1 20  ? -14.41972 -10.05283 -8.19277  1.000 38.92886 ? 18  PHE C C   1 
ATOM   4227 O  O   . PHE C 1 20  ? -15.24112 -10.85819 -7.73351  1.000 40.35418 ? 18  PHE C O   1 
ATOM   4228 C  CB  . PHE C 1 20  ? -12.30834 -10.05441 -9.60069  1.000 36.58990 ? 18  PHE C CB  1 
ATOM   4229 C  CG  . PHE C 1 20  ? -13.13884 -10.50281 -10.77273 1.000 36.67286 ? 18  PHE C CG  1 
ATOM   4230 C  CD1 . PHE C 1 20  ? -13.39360 -11.85180 -10.99347 1.000 41.57370 ? 18  PHE C CD1 1 
ATOM   4231 C  CD2 . PHE C 1 20  ? -13.64744 -9.57802  -11.66609 1.000 37.69973 ? 18  PHE C CD2 1 
ATOM   4232 C  CE1 . PHE C 1 20  ? -14.15127 -12.27126 -12.08543 1.000 41.78848 ? 18  PHE C CE1 1 
ATOM   4233 C  CE2 . PHE C 1 20  ? -14.39926 -9.98492  -12.75869 1.000 38.34670 ? 18  PHE C CE2 1 
ATOM   4234 C  CZ  . PHE C 1 20  ? -14.65545 -11.33398 -12.96320 1.000 44.63579 ? 18  PHE C CZ  1 
ATOM   4235 N  N   . ASP C 1 21  ? -14.76427 -8.86183  -8.67794  1.000 36.89417 ? 19  ASP C N   1 
ATOM   4236 C  CA  . ASP C 1 21  ? -16.12767 -8.32651  -8.63695  1.000 35.87169 ? 19  ASP C CA  1 
ATOM   4237 C  C   . ASP C 1 21  ? -16.68132 -8.34980  -7.21533  1.000 39.39780 ? 19  ASP C C   1 
ATOM   4238 O  O   . ASP C 1 21  ? -17.78452 -8.83097  -6.95679  1.000 36.84276 ? 19  ASP C O   1 
ATOM   4239 C  CB  . ASP C 1 21  ? -17.03868 -9.09404  -9.59051  1.000 39.95241 ? 19  ASP C CB  1 
ATOM   4240 C  CG  . ASP C 1 21  ? -18.33643 -8.36856  -9.86746  1.000 39.97424 ? 19  ASP C CG  1 
ATOM   4241 O  OD1 . ASP C 1 21  ? -18.46775 -7.20428  -9.45788  1.000 44.46472 ? 19  ASP C OD1 1 
ATOM   4242 O  OD2 . ASP C 1 21  ? -19.21617 -8.96051  -10.52228 1.000 48.92161 ? 19  ASP C OD2 1 
ATOM   4243 N  N   . ARG C 1 22  ? -15.88760 -7.84466  -6.27730  1.000 39.45565 ? 20  ARG C N   1 
ATOM   4244 C  CA  . ARG C 1 22  ? -16.31212 -7.80231  -4.88662  1.000 41.19865 ? 20  ARG C CA  1 
ATOM   4245 C  C   . ARG C 1 22  ? -17.05039 -6.52514  -4.54056  1.000 43.11862 ? 20  ARG C C   1 
ATOM   4246 O  O   . ARG C 1 22  ? -17.42005 -6.34385  -3.37848  1.000 41.20620 ? 20  ARG C O   1 
ATOM   4247 C  CB  . ARG C 1 22  ? -15.11202 -7.99766  -3.95392  1.000 42.02524 ? 20  ARG C CB  1 
ATOM   4248 C  CG  . ARG C 1 22  ? -14.76306 -9.47584  -3.77467  1.000 42.55756 ? 20  ARG C CG  1 
ATOM   4249 C  CD  . ARG C 1 22  ? -13.59929 -9.70005  -2.83341  1.000 46.63798 ? 20  ARG C CD  1 
ATOM   4250 N  NE  . ARG C 1 22  ? -12.82337 -8.47774  -2.70236  1.000 55.70946 ? 20  ARG C NE  1 
ATOM   4251 C  CZ  . ARG C 1 22  ? -12.63749 -7.81302  -1.57215  1.000 51.51395 ? 20  ARG C CZ  1 
ATOM   4252 N  NH1 . ARG C 1 22  ? -13.17408 -8.22117  -0.43128  1.000 53.12538 ? 20  ARG C NH1 1 
ATOM   4253 N  NH2 . ARG C 1 22  ? -11.89212 -6.71303  -1.58890  1.000 47.62127 ? 20  ARG C NH2 1 
ATOM   4254 N  N   . GLY C 1 23  ? -17.29055 -5.65364  -5.52163  1.000 41.72675 ? 21  GLY C N   1 
ATOM   4255 C  CA  . GLY C 1 23  ? -18.04722 -4.43745  -5.29371  1.000 42.14680 ? 21  GLY C CA  1 
ATOM   4256 C  C   . GLY C 1 23  ? -17.42221 -3.43665  -4.35194  1.000 39.08621 ? 21  GLY C C   1 
ATOM   4257 O  O   . GLY C 1 23  ? -18.13329 -2.58066  -3.82997  1.000 37.97301 ? 21  GLY C O   1 
ATOM   4258 N  N   . SER C 1 24  ? -16.12120 -3.52834  -4.09132  1.000 38.10180 ? 22  SER C N   1 
ATOM   4259 C  CA  . SER C 1 24  ? -15.45967 -2.50843  -3.28560  1.000 35.28048 ? 22  SER C CA  1 
ATOM   4260 C  C   . SER C 1 24  ? -15.42925 -1.17014  -4.01569  1.000 39.13889 ? 22  SER C C   1 
ATOM   4261 O  O   . SER C 1 24  ? -15.55627 -1.08906  -5.24826  1.000 36.99161 ? 22  SER C O   1 
ATOM   4262 C  CB  . SER C 1 24  ? -14.02932 -2.91840  -2.94973  1.000 38.66659 ? 22  SER C CB  1 
ATOM   4263 O  OG  . SER C 1 24  ? -13.20445 -2.82982  -4.10665  1.000 36.27790 ? 22  SER C OG  1 
ATOM   4264 N  N   . ASN C 1 25  ? -15.22992 -0.10021  -3.23733  1.000 34.78862 ? 23  ASN C N   1 
ATOM   4265 C  CA  . ASN C 1 25  ? -15.17759 1.21767   -3.85113  1.000 35.30295 ? 23  ASN C CA  1 
ATOM   4266 C  C   . ASN C 1 25  ? -13.94153 1.37728   -4.73622  1.000 36.16650 ? 23  ASN C C   1 
ATOM   4267 O  O   . ASN C 1 25  ? -13.99900 2.07066   -5.75676  1.000 36.78107 ? 23  ASN C O   1 
ATOM   4268 C  CB  . ASN C 1 25  ? -15.22825 2.30349   -2.77984  1.000 37.43067 ? 23  ASN C CB  1 
ATOM   4269 C  CG  . ASN C 1 25  ? -16.64684 2.58725   -2.33623  1.000 45.87363 ? 23  ASN C CG  1 
ATOM   4270 O  OD1 . ASN C 1 25  ? -17.55765 2.63559   -3.16558  1.000 47.38977 ? 23  ASN C OD1 1 
ATOM   4271 N  ND2 . ASN C 1 25  ? -16.84357 2.78739   -1.03771  1.000 41.38723 ? 23  ASN C ND2 1 
ATOM   4272 N  N   . TYR C 1 26  ? -12.81893 0.76145   -4.35795  1.000 33.33746 ? 24  TYR C N   1 
ATOM   4273 C  CA  . TYR C 1 26  ? -11.67821 0.66195   -5.26661  1.000 35.23683 ? 24  TYR C CA  1 
ATOM   4274 C  C   . TYR C 1 26  ? -12.09464 0.14523   -6.64748  1.000 34.65834 ? 24  TYR C C   1 
ATOM   4275 O  O   . TYR C 1 26  ? -11.78312 0.76506   -7.67690  1.000 33.90596 ? 24  TYR C O   1 
ATOM   4276 C  CB  . TYR C 1 26  ? -10.61019 -0.24306  -4.65370  1.000 35.91542 ? 24  TYR C CB  1 
ATOM   4277 C  CG  . TYR C 1 26  ? -9.39538  -0.45491  -5.53798  1.000 36.13604 ? 24  TYR C CG  1 
ATOM   4278 C  CD1 . TYR C 1 26  ? -8.32935  0.44574   -5.49783  1.000 33.81064 ? 24  TYR C CD1 1 
ATOM   4279 C  CD2 . TYR C 1 26  ? -9.29356  -1.56985  -6.37921  1.000 34.27735 ? 24  TYR C CD2 1 
ATOM   4280 C  CE1 . TYR C 1 26  ? -7.19474  0.26958   -6.29035  1.000 31.45017 ? 24  TYR C CE1 1 
ATOM   4281 C  CE2 . TYR C 1 26  ? -8.15561  -1.76720  -7.18055  1.000 34.12081 ? 24  TYR C CE2 1 
ATOM   4282 C  CZ  . TYR C 1 26  ? -7.11303  -0.82863  -7.13394  1.000 32.69921 ? 24  TYR C CZ  1 
ATOM   4283 O  OH  . TYR C 1 26  ? -5.98257  -1.00555  -7.90549  1.000 30.33986 ? 24  TYR C OH  1 
ATOM   4284 N  N   . GLU C 1 27  ? -12.78013 -1.00421  -6.69274  1.000 34.55577 ? 25  GLU C N   1 
ATOM   4285 C  CA  . GLU C 1 27  ? -13.24679 -1.53906  -7.97484  1.000 34.81693 ? 25  GLU C CA  1 
ATOM   4286 C  C   . GLU C 1 27  ? -14.32441 -0.65443  -8.61219  1.000 35.80299 ? 25  GLU C C   1 
ATOM   4287 O  O   . GLU C 1 27  ? -14.33604 -0.48884  -9.83871  1.000 35.14611 ? 25  GLU C O   1 
ATOM   4288 C  CB  . GLU C 1 27  ? -13.74252 -2.98563  -7.80662  1.000 35.76806 ? 25  GLU C CB  1 
ATOM   4289 C  CG  . GLU C 1 27  ? -12.79199 -3.88761  -7.02321  1.000 32.07046 ? 25  GLU C CG  1 
ATOM   4290 C  CD  . GLU C 1 27  ? -13.46691 -5.18014  -6.57506  1.000 39.89070 ? 25  GLU C CD  1 
ATOM   4291 O  OE1 . GLU C 1 27  ? -13.47650 -6.24042  -7.28186  1.000 37.63422 ? 25  GLU C OE1 1 
ATOM   4292 O  OE2 . GLU C 1 27  ? -14.06285 -5.08264  -5.48289  1.000 37.96311 ? 25  GLU C OE2 1 
ATOM   4293 N  N   . ASN C 1 28  ? -15.24191 -0.08870  -7.81312  1.000 33.63150 ? 26  ASN C N   1 
ATOM   4294 C  CA  . ASN C 1 28  ? -16.28313 0.78311   -8.36943  1.000 35.85509 ? 26  ASN C CA  1 
ATOM   4295 C  C   . ASN C 1 28  ? -15.68355 1.98887   -9.07925  1.000 36.69296 ? 26  ASN C C   1 
ATOM   4296 O  O   . ASN C 1 28  ? -16.05849 2.30550   -10.21378 1.000 35.92684 ? 26  ASN C O   1 
ATOM   4297 C  CB  . ASN C 1 28  ? -17.25805 1.27932   -7.27551  1.000 37.13010 ? 26  ASN C CB  1 
ATOM   4298 C  CG  . ASN C 1 28  ? -17.96594 0.14291   -6.52910  1.000 41.55263 ? 26  ASN C CG  1 
ATOM   4299 O  OD1 . ASN C 1 28  ? -18.16592 -0.94652  -7.06721  1.000 42.82698 ? 26  ASN C OD1 1 
ATOM   4300 N  ND2 . ASN C 1 28  ? -18.34956 0.40665   -5.28002  1.000 41.13776 ? 26  ASN C ND2 1 
ATOM   4301 N  N   . VAL C 1 29  ? -14.77957 2.70010   -8.40058  1.000 33.88223 ? 27  VAL C N   1 
ATOM   4302 C  CA  . VAL C 1 29  ? -14.19892 3.91193   -8.96463  1.000 34.09360 ? 27  VAL C CA  1 
ATOM   4303 C  C   . VAL C 1 29  ? -13.49991 3.60129   -10.28303 1.000 36.22231 ? 27  VAL C C   1 
ATOM   4304 O  O   . VAL C 1 29  ? -13.59567 4.36839   -11.24713 1.000 34.15352 ? 27  VAL C O   1 
ATOM   4305 C  CB  . VAL C 1 29  ? -13.23882 4.55650   -7.94831  1.000 35.62391 ? 27  VAL C CB  1 
ATOM   4306 C  CG1 . VAL C 1 29  ? -12.37568 5.61093   -8.61909  1.000 34.98742 ? 27  VAL C CG1 1 
ATOM   4307 C  CG2 . VAL C 1 29  ? -14.02082 5.16046   -6.75898  1.000 34.22661 ? 27  VAL C CG2 1 
ATOM   4308 N  N   . LEU C 1 30  ? -12.82422 2.45331   -10.36015 1.000 32.09997 ? 28  LEU C N   1 
ATOM   4309 C  CA  . LEU C 1 30  ? -11.97871 2.13886   -11.50605 1.000 33.93312 ? 28  LEU C CA  1 
ATOM   4310 C  C   . LEU C 1 30  ? -12.71760 1.47837   -12.66647 1.000 33.69877 ? 28  LEU C C   1 
ATOM   4311 O  O   . LEU C 1 30  ? -12.11817 1.31550   -13.74176 1.000 31.75220 ? 28  LEU C O   1 
ATOM   4312 C  CB  . LEU C 1 30  ? -10.82568 1.22889   -11.06563 1.000 31.64475 ? 28  LEU C CB  1 
ATOM   4313 C  CG  . LEU C 1 30  ? -9.83526  1.87679   -10.09490 1.000 33.09298 ? 28  LEU C CG  1 
ATOM   4314 C  CD1 . LEU C 1 30  ? -8.77385  0.87518   -9.65414  1.000 31.92229 ? 28  LEU C CD1 1 
ATOM   4315 C  CD2 . LEU C 1 30  ? -9.17661  3.13348   -10.72047 1.000 33.32520 ? 28  LEU C CD2 1 
ATOM   4316 N  N   . HIS C 1 31  ? -13.99104 1.10307   -12.48913 1.000 32.65694 ? 29  HIS C N   1 
ATOM   4317 C  CA  . HIS C 1 31  ? -14.69573 0.27279   -13.46348 1.000 36.15544 ? 29  HIS C CA  1 
ATOM   4318 C  C   . HIS C 1 31  ? -13.91421 -1.02334  -13.71276 1.000 34.59763 ? 29  HIS C C   1 
ATOM   4319 O  O   . HIS C 1 31  ? -13.82943 -1.51588  -14.83955 1.000 33.00765 ? 29  HIS C O   1 
ATOM   4320 C  CB  . HIS C 1 31  ? -14.92187 1.01850   -14.78927 1.000 35.38198 ? 29  HIS C CB  1 
ATOM   4321 C  CG  . HIS C 1 31  ? -15.83127 2.21075   -14.70072 1.000 38.64953 ? 29  HIS C CG  1 
ATOM   4322 N  ND1 . HIS C 1 31  ? -15.72157 3.17389   -13.71761 1.000 41.31208 ? 29  HIS C ND1 1 
ATOM   4323 C  CD2 . HIS C 1 31  ? -16.83585 2.62068   -15.51423 1.000 38.12814 ? 29  HIS C CD2 1 
ATOM   4324 C  CE1 . HIS C 1 31  ? -16.63386 4.10968   -13.91669 1.000 38.39483 ? 29  HIS C CE1 1 
ATOM   4325 N  NE2 . HIS C 1 31  ? -17.32363 3.80039   -14.99923 1.000 42.64368 ? 29  HIS C NE2 1 
ATOM   4326 N  N   . LEU C 1 32  ? -13.28481 -1.55071  -12.65804 1.000 30.58079 ? 30  LEU C N   1 
ATOM   4327 C  CA  . LEU C 1 32  ? -12.33611 -2.64867  -12.83826 1.000 33.33009 ? 30  LEU C CA  1 
ATOM   4328 C  C   . LEU C 1 32  ? -13.02552 -3.93272  -13.29206 1.000 36.91616 ? 30  LEU C C   1 
ATOM   4329 O  O   . LEU C 1 32  ? -12.48328 -4.69345  -14.10889 1.000 31.67426 ? 30  LEU C O   1 
ATOM   4330 C  CB  . LEU C 1 32  ? -11.58990 -2.91048  -11.53804 1.000 35.23770 ? 30  LEU C CB  1 
ATOM   4331 C  CG  . LEU C 1 32  ? -10.53580 -4.01064  -11.61956 1.000 33.01434 ? 30  LEU C CG  1 
ATOM   4332 C  CD1 . LEU C 1 32  ? -9.65170  -3.90351  -12.88421 1.000 28.63904 ? 30  LEU C CD1 1 
ATOM   4333 C  CD2 . LEU C 1 32  ? -9.71773  -4.00562  -10.36172 1.000 32.34456 ? 30  LEU C CD2 1 
ATOM   4334 N  N   . THR C 1 33  ? -14.21274 -4.20259  -12.76395 1.000 33.43113 ? 31  THR C N   1 
ATOM   4335 C  CA  . THR C 1 33  ? -14.89283 -5.42762  -13.15207 1.000 36.04244 ? 31  THR C CA  1 
ATOM   4336 C  C   . THR C 1 33  ? -15.19724 -5.42603  -14.64449 1.000 36.65448 ? 31  THR C C   1 
ATOM   4337 O  O   . THR C 1 33  ? -14.97122 -6.43204  -15.33514 1.000 37.18035 ? 31  THR C O   1 
ATOM   4338 C  CB  . THR C 1 33  ? -16.14729 -5.59283  -12.29699 1.000 34.12704 ? 31  THR C CB  1 
ATOM   4339 O  OG1 . THR C 1 33  ? -15.73704 -5.81657  -10.94002 1.000 35.32362 ? 31  THR C OG1 1 
ATOM   4340 C  CG2 . THR C 1 33  ? -16.99370 -6.73529  -12.77571 1.000 37.20022 ? 31  THR C CG2 1 
ATOM   4341 N  N   . ASP C 1 34  ? -15.67206 -4.29736  -15.16975 1.000 33.59055 ? 32  ASP C N   1 
ATOM   4342 C  CA  . ASP C 1 34  ? -15.92079 -4.21114  -16.60855 1.000 37.78393 ? 32  ASP C CA  1 
ATOM   4343 C  C   . ASP C 1 34  ? -14.64063 -4.42029  -17.40545 1.000 37.16931 ? 32  ASP C C   1 
ATOM   4344 O  O   . ASP C 1 34  ? -14.64961 -5.06819  -18.45978 1.000 36.60993 ? 32  ASP C O   1 
ATOM   4345 C  CB  . ASP C 1 34  ? -16.55175 -2.85663  -16.95966 1.000 37.94328 ? 32  ASP C CB  1 
ATOM   4346 C  CG  . ASP C 1 34  ? -18.05142 -2.80002  -16.64260 1.000 39.50676 ? 32  ASP C CG  1 
ATOM   4347 O  OD1 . ASP C 1 34  ? -18.64499 -3.84781  -16.35206 1.000 41.47885 ? 32  ASP C OD1 1 
ATOM   4348 O  OD2 . ASP C 1 34  ? -18.63228 -1.70030  -16.67316 1.000 44.24082 ? 32  ASP C OD2 1 
ATOM   4349 N  N   . ALA C 1 35  ? -13.52566 -3.88096  -16.92253 1.000 36.14716 ? 33  ALA C N   1 
ATOM   4350 C  CA  . ALA C 1 35  ? -12.28663 -4.00752  -17.68235 1.000 37.01323 ? 33  ALA C CA  1 
ATOM   4351 C  C   . ALA C 1 35  ? -11.77084 -5.44112  -17.65520 1.000 37.30840 ? 33  ALA C C   1 
ATOM   4352 O  O   . ALA C 1 35  ? -11.28318 -5.95116  -18.67355 1.000 34.67590 ? 33  ALA C O   1 
ATOM   4353 C  CB  . ALA C 1 35  ? -11.23423 -3.03337  -17.14239 1.000 33.94663 ? 33  ALA C CB  1 
ATOM   4354 N  N   . LEU C 1 36  ? -11.88775 -6.11389  -16.50440 1.000 34.55017 ? 34  LEU C N   1 
ATOM   4355 C  CA  . LEU C 1 36  ? -11.47126 -7.51574  -16.40874 1.000 34.52171 ? 34  LEU C CA  1 
ATOM   4356 C  C   . LEU C 1 36  ? -12.36249 -8.42875  -17.24667 1.000 34.34234 ? 34  LEU C C   1 
ATOM   4357 O  O   . LEU C 1 36  ? -11.90919 -9.48700  -17.70039 1.000 31.35160 ? 34  LEU C O   1 
ATOM   4358 C  CB  . LEU C 1 36  ? -11.49043 -7.96637  -14.93872 1.000 38.44699 ? 34  LEU C CB  1 
ATOM   4359 C  CG  . LEU C 1 36  ? -10.39676 -7.35069  -14.05430 1.000 36.30359 ? 34  LEU C CG  1 
ATOM   4360 C  CD1 . LEU C 1 36  ? -10.48592 -7.77591  -12.59389 1.000 35.03404 ? 34  LEU C CD1 1 
ATOM   4361 C  CD2 . LEU C 1 36  ? -9.02496  -7.67813  -14.62949 1.000 39.58046 ? 34  LEU C CD2 1 
ATOM   4362 N  N   . GLY C 1 37  ? -13.62406 -8.03813  -17.46252 1.000 35.16532 ? 35  GLY C N   1 
ATOM   4363 C  CA  . GLY C 1 37  ? -14.55164 -8.79519  -18.28919 1.000 34.51067 ? 35  GLY C CA  1 
ATOM   4364 C  C   . GLY C 1 37  ? -14.20631 -8.80157  -19.76882 1.000 36.24130 ? 35  GLY C C   1 
ATOM   4365 O  O   . GLY C 1 37  ? -14.79866 -9.57590  -20.52871 1.000 35.79717 ? 35  GLY C O   1 
ATOM   4366 N  N   . ALA C 1 38  ? -13.26840 -7.95823  -20.19076 1.000 33.79649 ? 36  ALA C N   1 
ATOM   4367 C  CA  . ALA C 1 38  ? -12.78447 -8.01376  -21.55929 1.000 35.90376 ? 36  ALA C CA  1 
ATOM   4368 C  C   . ALA C 1 38  ? -11.83778 -9.18746  -21.78438 1.000 32.65960 ? 36  ALA C C   1 
ATOM   4369 O  O   . ALA C 1 38  ? -11.61087 -9.56986  -22.93401 1.000 32.61668 ? 36  ALA C O   1 
ATOM   4370 C  CB  . ALA C 1 38  ? -12.09476 -6.68369  -21.91849 1.000 34.09038 ? 36  ALA C CB  1 
ATOM   4371 N  N   . LEU C 1 39  ? -11.27895 -9.76187  -20.72073 1.000 33.59556 ? 37  LEU C N   1 
ATOM   4372 C  CA  . LEU C 1 39  ? -10.34154 -10.86797 -20.88894 1.000 34.66851 ? 37  LEU C CA  1 
ATOM   4373 C  C   . LEU C 1 39  ? -11.04828 -12.07333 -21.49700 1.000 36.95481 ? 37  LEU C C   1 
ATOM   4374 O  O   . LEU C 1 39  ? -12.18311 -12.40203 -21.12698 1.000 32.32548 ? 37  LEU C O   1 
ATOM   4375 C  CB  . LEU C 1 39  ? -9.71534  -11.24587 -19.54925 1.000 33.32003 ? 37  LEU C CB  1 
ATOM   4376 C  CG  . LEU C 1 39  ? -8.79598  -10.17493 -18.94271 1.000 37.37180 ? 37  LEU C CG  1 
ATOM   4377 C  CD1 . LEU C 1 39  ? -8.32052  -10.63319 -17.59038 1.000 37.39729 ? 37  LEU C CD1 1 
ATOM   4378 C  CD2 . LEU C 1 39  ? -7.59256  -9.89557  -19.87126 1.000 38.21969 ? 37  LEU C CD2 1 
ATOM   4379 N  N   . VAL C 1 40  ? -10.38861 -12.71433 -22.45798 1.000 33.00449 ? 38  VAL C N   1 
ATOM   4380 C  CA  . VAL C 1 40  ? -11.03511 -13.88540 -23.05949 1.000 35.13879 ? 38  VAL C CA  1 
ATOM   4381 C  C   . VAL C 1 40  ? -11.26644 -14.92153 -21.96928 1.000 36.79400 ? 38  VAL C C   1 
ATOM   4382 O  O   . VAL C 1 40  ? -10.34277 -15.21008 -21.17731 1.000 34.59890 ? 38  VAL C O   1 
ATOM   4383 C  CB  . VAL C 1 40  ? -10.18161 -14.45751 -24.20071 1.000 37.54665 ? 38  VAL C CB  1 
ATOM   4384 C  CG1 . VAL C 1 40  ? -10.47804 -15.91920 -24.42347 1.000 42.83188 ? 38  VAL C CG1 1 
ATOM   4385 C  CG2 . VAL C 1 40  ? -10.40065 -13.65080 -25.49813 1.000 39.03746 ? 38  VAL C CG2 1 
ATOM   4386 N  N   . PRO C 1 41  ? -12.47481 -15.46950 -21.84644 1.000 40.46241 ? 39  PRO C N   1 
ATOM   4387 C  CA  . PRO C 1 41  ? -12.75069 -16.41083 -20.75116 1.000 40.71793 ? 39  PRO C CA  1 
ATOM   4388 C  C   . PRO C 1 41  ? -11.89786 -17.67096 -20.85018 1.000 39.29365 ? 39  PRO C C   1 
ATOM   4389 O  O   . PRO C 1 41  ? -11.59980 -18.16904 -21.94467 1.000 38.58533 ? 39  PRO C O   1 
ATOM   4390 C  CB  . PRO C 1 41  ? -14.24542 -16.71373 -20.90896 1.000 40.89957 ? 39  PRO C CB  1 
ATOM   4391 C  CG  . PRO C 1 41  ? -14.79154 -15.50395 -21.67753 1.000 42.30680 ? 39  PRO C CG  1 
ATOM   4392 C  CD  . PRO C 1 41  ? -13.68478 -15.10083 -22.60146 1.000 39.11876 ? 39  PRO C CD  1 
ATOM   4393 N  N   . GLU C 1 42  ? -11.49037 -18.17189 -19.67727 1.000 35.10653 ? 40  GLU C N   1 
ATOM   4394 C  CA  . GLU C 1 42  ? -10.56477 -19.30070 -19.63772 1.000 43.63636 ? 40  GLU C CA  1 
ATOM   4395 C  C   . GLU C 1 42  ? -11.11858 -20.50694 -20.38999 1.000 41.51485 ? 40  GLU C C   1 
ATOM   4396 O  O   . GLU C 1 42  ? -10.36752 -21.21944 -21.06507 1.000 38.86255 ? 40  GLU C O   1 
ATOM   4397 C  CB  . GLU C 1 42  ? -10.24239 -19.67251 -18.19345 1.000 43.21228 ? 40  GLU C CB  1 
ATOM   4398 C  CG  . GLU C 1 42  ? -9.36203  -18.64429 -17.47049 1.000 40.02826 ? 40  GLU C CG  1 
ATOM   4399 C  CD  . GLU C 1 42  ? -8.48719  -19.29069 -16.41167 1.000 42.84603 ? 40  GLU C CD  1 
ATOM   4400 O  OE1 . GLU C 1 42  ? -8.31771  -20.53094 -16.44595 1.000 45.90520 ? 40  GLU C OE1 1 
ATOM   4401 O  OE2 . GLU C 1 42  ? -7.97825  -18.56535 -15.53682 1.000 45.79955 ? 40  GLU C OE2 1 
ATOM   4402 N  N   . SER C 1 43  ? -12.43409 -20.72202 -20.32348 1.000 40.30541 ? 41  SER C N   1 
ATOM   4403 C  CA  . SER C 1 43  ? -13.05339 -21.82832 -21.04321 1.000 41.06811 ? 41  SER C CA  1 
ATOM   4404 C  C   . SER C 1 43  ? -13.03454 -21.64704 -22.55505 1.000 42.44329 ? 41  SER C C   1 
ATOM   4405 O  O   . SER C 1 43  ? -13.37853 -22.58871 -23.27422 1.000 43.68618 ? 41  SER C O   1 
ATOM   4406 C  CB  . SER C 1 43  ? -14.50064 -22.02201 -20.56614 1.000 41.04688 ? 41  SER C CB  1 
ATOM   4407 O  OG  . SER C 1 43  ? -15.34117 -20.97918 -21.04831 1.000 46.08301 ? 41  SER C OG  1 
ATOM   4408 N  N   . GLU C 1 44  ? -12.67284 -20.47214 -23.06882 1.000 41.87243 ? 42  GLU C N   1 
ATOM   4409 C  CA  . GLU C 1 44  ? -12.64167 -20.28781 -24.51373 1.000 44.79092 ? 42  GLU C CA  1 
ATOM   4410 C  C   . GLU C 1 44  ? -11.23963 -20.17811 -25.09464 1.000 41.93783 ? 42  GLU C C   1 
ATOM   4411 O  O   . GLU C 1 44  ? -11.09444 -20.28242 -26.32054 1.000 45.08129 ? 42  GLU C O   1 
ATOM   4412 C  CB  . GLU C 1 44  ? -13.46137 -19.05394 -24.92205 1.000 42.61220 ? 42  GLU C CB  1 
ATOM   4413 C  CG  . GLU C 1 44  ? -14.89403 -19.09587 -24.41118 1.000 46.44882 ? 42  GLU C CG  1 
ATOM   4414 C  CD  . GLU C 1 44  ? -15.71922 -17.88626 -24.83019 1.000 51.63119 ? 42  GLU C CD  1 
ATOM   4415 O  OE1 . GLU C 1 44  ? -15.21548 -17.03847 -25.60474 1.000 51.91064 ? 42  GLU C OE1 1 
ATOM   4416 O  OE2 . GLU C 1 44  ? -16.87991 -17.78036 -24.37934 1.000 56.55000 ? 42  GLU C OE2 1 
ATOM   4417 N  N   . THR C 1 45  ? -10.21137 -19.98328 -24.26594 1.000 40.43378 ? 43  THR C N   1 
ATOM   4418 C  CA  . THR C 1 45  ? -8.85731  -19.87996 -24.79352 1.000 42.06363 ? 43  THR C CA  1 
ATOM   4419 C  C   . THR C 1 45  ? -8.45749  -21.16618 -25.51184 1.000 43.53221 ? 43  THR C C   1 
ATOM   4420 O  O   . THR C 1 45  ? -8.76460  -22.27919 -25.07083 1.000 43.28253 ? 43  THR C O   1 
ATOM   4421 C  CB  . THR C 1 45  ? -7.84810  -19.54588 -23.68486 1.000 38.61363 ? 43  THR C CB  1 
ATOM   4422 O  OG1 . THR C 1 45  ? -7.78539  -20.62017 -22.73334 1.000 36.97694 ? 43  THR C OG1 1 
ATOM   4423 C  CG2 . THR C 1 45  ? -8.15466  -18.22880 -23.00255 1.000 38.72287 ? 43  THR C CG2 1 
ATOM   4424 N  N   . GLU C 1 46  ? -7.78792  -20.99414 -26.64732 1.000 43.48022 ? 44  GLU C N   1 
ATOM   4425 C  CA  . GLU C 1 46  ? -7.35123  -22.08959 -27.49303 1.000 43.16683 ? 44  GLU C CA  1 
ATOM   4426 C  C   . GLU C 1 46  ? -5.85912  -22.37280 -27.36322 1.000 43.69339 ? 44  GLU C C   1 
ATOM   4427 O  O   . GLU C 1 46  ? -5.36000  -23.28642 -28.01859 1.000 41.09055 ? 44  GLU C O   1 
ATOM   4428 C  CB  . GLU C 1 46  ? -7.69718  -21.76824 -28.95164 1.000 52.69417 ? 44  GLU C CB  1 
ATOM   4429 C  CG  . GLU C 1 46  ? -9.13976  -22.09498 -29.32862 1.000 57.72797 ? 44  GLU C CG  1 
ATOM   4430 C  CD  . GLU C 1 46  ? -9.41515  -21.93814 -30.82554 1.000 68.23744 ? 44  GLU C CD  1 
ATOM   4431 O  OE1 . GLU C 1 46  ? -10.57983 -21.63848 -31.18088 1.000 74.38637 ? 44  GLU C OE1 1 
ATOM   4432 O  OE2 . GLU C 1 46  ? -8.47539  -22.08512 -31.64126 1.000 65.22193 ? 44  GLU C OE2 1 
ATOM   4433 N  N   . HIS C 1 47  ? -5.13345  -21.60451 -26.54482 1.000 40.12760 ? 45  HIS C N   1 
ATOM   4434 C  CA  . HIS C 1 47  ? -3.70338  -21.80444 -26.33454 1.000 36.41105 ? 45  HIS C CA  1 
ATOM   4435 C  C   . HIS C 1 47  ? -3.35031  -21.14957 -25.01087 1.000 32.27114 ? 45  HIS C C   1 
ATOM   4436 O  O   . HIS C 1 47  ? -3.93984  -20.11861 -24.69315 1.000 32.17707 ? 45  HIS C O   1 
ATOM   4437 C  CB  . HIS C 1 47  ? -2.86164  -21.20545 -27.47251 1.000 32.50446 ? 45  HIS C CB  1 
ATOM   4438 C  CG  . HIS C 1 47  ? -1.43441  -21.63506 -27.41904 1.000 32.84379 ? 45  HIS C CG  1 
ATOM   4439 N  ND1 . HIS C 1 47  ? -0.52477  -21.04546 -26.57102 1.000 30.20374 ? 45  HIS C ND1 1 
ATOM   4440 C  CD2 . HIS C 1 47  ? -0.77676  -22.65084 -28.03508 1.000 33.26685 ? 45  HIS C CD2 1 
ATOM   4441 C  CE1 . HIS C 1 47  ? 0.63484   -21.67243 -26.66974 1.000 31.84348 ? 45  HIS C CE1 1 
ATOM   4442 N  NE2 . HIS C 1 47  ? 0.51752   -22.63065 -27.57403 1.000 31.30511 ? 45  HIS C NE2 1 
ATOM   4443 N  N   . PRO C 1 48  ? -2.45237  -21.72333 -24.19782 1.000 30.91726 ? 46  PRO C N   1 
ATOM   4444 C  CA  . PRO C 1 48  ? -2.16998  -21.11002 -22.88607 1.000 28.35832 ? 46  PRO C CA  1 
ATOM   4445 C  C   . PRO C 1 48  ? -1.42329  -19.79345 -22.98305 1.000 30.32777 ? 46  PRO C C   1 
ATOM   4446 O  O   . PRO C 1 48  ? -1.41595  -19.03044 -22.00462 1.000 28.96958 ? 46  PRO C O   1 
ATOM   4447 C  CB  . PRO C 1 48  ? -1.31914  -22.15419 -22.15713 1.000 30.73330 ? 46  PRO C CB  1 
ATOM   4448 C  CG  . PRO C 1 48  ? -0.91477  -23.18659 -23.19649 1.000 35.88989 ? 46  PRO C CG  1 
ATOM   4449 C  CD  . PRO C 1 48  ? -1.67971  -22.95372 -24.45269 1.000 34.35496 ? 46  PRO C CD  1 
ATOM   4450 N  N   . ASP C 1 49  ? -0.77128  -19.51138 -24.11836 1.000 29.32495 ? 47  ASP C N   1 
ATOM   4451 C  CA  . ASP C 1 49  ? -0.15272  -18.20519 -24.31474 1.000 27.77899 ? 47  ASP C CA  1 
ATOM   4452 C  C   . ASP C 1 49  ? -1.11856  -17.15914 -24.85700 1.000 30.45948 ? 47  ASP C C   1 
ATOM   4453 O  O   . ASP C 1 49  ? -0.72164  -15.99789 -25.01600 1.000 29.05319 ? 47  ASP C O   1 
ATOM   4454 C  CB  . ASP C 1 49  ? 1.07436   -18.33992 -25.23474 1.000 27.92554 ? 47  ASP C CB  1 
ATOM   4455 C  CG  . ASP C 1 49  ? 2.20875   -19.07183 -24.54900 1.000 31.53630 ? 47  ASP C CG  1 
ATOM   4456 O  OD1 . ASP C 1 49  ? 2.33208   -18.91591 -23.31258 1.000 31.19578 ? 47  ASP C OD1 1 
ATOM   4457 O  OD2 . ASP C 1 49  ? 2.94820   -19.82711 -25.21243 1.000 30.48213 ? 47  ASP C OD2 1 
ATOM   4458 N  N   . GLN C 1 50  ? -2.37423  -17.51855 -25.12419 1.000 29.46359 ? 48  GLN C N   1 
ATOM   4459 C  CA  . GLN C 1 50  ? -3.31088  -16.54630 -25.68855 1.000 28.62699 ? 48  GLN C CA  1 
ATOM   4460 C  C   . GLN C 1 50  ? -3.58595  -15.37198 -24.73957 1.000 31.00005 ? 48  GLN C C   1 
ATOM   4461 O  O   . GLN C 1 50  ? -3.70946  -14.21900 -25.18594 1.000 29.30808 ? 48  GLN C O   1 
ATOM   4462 C  CB  . GLN C 1 50  ? -4.60613  -17.26068 -26.07034 1.000 29.87186 ? 48  GLN C CB  1 
ATOM   4463 C  CG  . GLN C 1 50  ? -5.69865  -16.34726 -26.61814 1.000 32.63960 ? 48  GLN C CG  1 
ATOM   4464 C  CD  . GLN C 1 50  ? -6.91116  -17.14959 -27.06448 1.000 39.51316 ? 48  GLN C CD  1 
ATOM   4465 O  OE1 . GLN C 1 50  ? -6.83184  -18.37425 -27.15440 1.000 42.96399 ? 48  GLN C OE1 1 
ATOM   4466 N  NE2 . GLN C 1 50  ? -8.04982  -16.47664 -27.29074 1.000 37.73562 ? 48  GLN C NE2 1 
ATOM   4467 N  N   . ARG C 1 51  ? -3.71411  -15.63680 -23.43195 1.000 30.15315 ? 49  ARG C N   1 
ATOM   4468 C  CA  . ARG C 1 51  ? -3.98953  -14.55035 -22.49638 1.000 27.69576 ? 49  ARG C CA  1 
ATOM   4469 C  C   . ARG C 1 51  ? -2.84339  -13.54628 -22.46384 1.000 28.52410 ? 49  ARG C C   1 
ATOM   4470 O  O   . ARG C 1 51  ? -3.06698  -12.33526 -22.46127 1.000 30.24823 ? 49  ARG C O   1 
ATOM   4471 C  CB  . ARG C 1 51  ? -4.24203  -15.09961 -21.09363 1.000 28.62621 ? 49  ARG C CB  1 
ATOM   4472 C  CG  . ARG C 1 51  ? -5.70328  -15.43528 -20.79774 1.000 30.56839 ? 49  ARG C CG  1 
ATOM   4473 C  CD  . ARG C 1 51  ? -6.56404  -14.15540 -20.59645 1.000 30.74522 ? 49  ARG C CD  1 
ATOM   4474 N  NE  . ARG C 1 51  ? -7.89548  -14.54043 -20.16558 1.000 31.83084 ? 49  ARG C NE  1 
ATOM   4475 C  CZ  . ARG C 1 51  ? -8.19953  -14.83552 -18.90892 1.000 35.84916 ? 49  ARG C CZ  1 
ATOM   4476 N  NH1 . ARG C 1 51  ? -7.30215  -14.72717 -17.94087 1.000 31.95662 ? 49  ARG C NH1 1 
ATOM   4477 N  NH2 . ARG C 1 51  ? -9.43413  -15.24410 -18.61604 1.000 38.16990 ? 49  ARG C NH2 1 
ATOM   4478 N  N   . PHE C 1 52  ? -1.60513  -14.03321 -22.38488 1.000 28.71879 ? 50  PHE C N   1 
ATOM   4479 C  CA  . PHE C 1 52  ? -0.45580  -13.13142 -22.39782 1.000 26.36461 ? 50  PHE C CA  1 
ATOM   4480 C  C   . PHE C 1 52  ? -0.48113  -12.25265 -23.64542 1.000 29.14596 ? 50  PHE C C   1 
ATOM   4481 O  O   . PHE C 1 52  ? -0.33661  -11.03377 -23.56106 1.000 25.76804 ? 50  PHE C O   1 
ATOM   4482 C  CB  . PHE C 1 52  ? 0.82053   -13.97176 -22.30637 1.000 28.10185 ? 50  PHE C CB  1 
ATOM   4483 C  CG  . PHE C 1 52  ? 2.09821   -13.19808 -22.35740 1.000 28.75404 ? 50  PHE C CG  1 
ATOM   4484 C  CD1 . PHE C 1 52  ? 2.40845   -12.26176 -21.37942 1.000 30.77264 ? 50  PHE C CD1 1 
ATOM   4485 C  CD2 . PHE C 1 52  ? 3.02281   -13.44944 -23.35316 1.000 26.60224 ? 50  PHE C CD2 1 
ATOM   4486 C  CE1 . PHE C 1 52  ? 3.61162   -11.55349 -21.41449 1.000 28.56163 ? 50  PHE C CE1 1 
ATOM   4487 C  CE2 . PHE C 1 52  ? 4.23899   -12.75582 -23.39339 1.000 33.40319 ? 50  PHE C CE2 1 
ATOM   4488 C  CZ  . PHE C 1 52  ? 4.52509   -11.80687 -22.42536 1.000 31.03706 ? 50  PHE C CZ  1 
ATOM   4489 N  N   . PHE C 1 53  ? -0.72853  -12.85906 -24.80758 1.000 30.15975 ? 51  PHE C N   1 
ATOM   4490 C  CA  . PHE C 1 53  ? -0.85695  -12.11432 -26.06418 1.000 29.82137 ? 51  PHE C CA  1 
ATOM   4491 C  C   . PHE C 1 53  ? -1.91178  -10.99737 -25.96111 1.000 29.42109 ? 51  PHE C C   1 
ATOM   4492 O  O   . PHE C 1 53  ? -1.64014  -9.82486  -26.27767 1.000 30.51211 ? 51  PHE C O   1 
ATOM   4493 C  CB  . PHE C 1 53  ? -1.20176  -13.15531 -27.14100 1.000 33.77992 ? 51  PHE C CB  1 
ATOM   4494 C  CG  . PHE C 1 53  ? -1.45676  -12.61011 -28.52541 1.000 29.56269 ? 51  PHE C CG  1 
ATOM   4495 C  CD1 . PHE C 1 53  ? -2.71977  -12.14966 -28.88858 1.000 30.07642 ? 51  PHE C CD1 1 
ATOM   4496 C  CD2 . PHE C 1 53  ? -0.47566  -12.67982 -29.48740 1.000 33.81418 ? 51  PHE C CD2 1 
ATOM   4497 C  CE1 . PHE C 1 53  ? -2.96538  -11.71036 -30.18844 1.000 34.96650 ? 51  PHE C CE1 1 
ATOM   4498 C  CE2 . PHE C 1 53  ? -0.70313  -12.22680 -30.79503 1.000 33.27854 ? 51  PHE C CE2 1 
ATOM   4499 C  CZ  . PHE C 1 53  ? -1.94827  -11.74631 -31.14416 1.000 31.89269 ? 51  PHE C CZ  1 
ATOM   4500 N  N   . GLN C 1 54  ? -3.11547  -11.33386 -25.47136 1.000 28.43529 ? 52  GLN C N   1 
ATOM   4501 C  CA  . GLN C 1 54  ? -4.18931  -10.34417 -25.41428 1.000 31.43219 ? 52  GLN C CA  1 
ATOM   4502 C  C   . GLN C 1 54  ? -3.85172  -9.23405  -24.43518 1.000 29.06747 ? 52  GLN C C   1 
ATOM   4503 O  O   . GLN C 1 54  ? -4.06774  -8.05250  -24.72816 1.000 28.07922 ? 52  GLN C O   1 
ATOM   4504 C  CB  . GLN C 1 54  ? -5.52368  -10.98084 -25.00969 1.000 32.03797 ? 52  GLN C CB  1 
ATOM   4505 C  CG  . GLN C 1 54  ? -6.62171  -9.91615  -24.77424 1.000 31.08264 ? 52  GLN C CG  1 
ATOM   4506 C  CD  . GLN C 1 54  ? -7.94116  -10.51163 -24.21168 1.000 35.97734 ? 52  GLN C CD  1 
ATOM   4507 O  OE1 . GLN C 1 54  ? -7.92248  -11.50644 -23.49795 1.000 35.05180 ? 52  GLN C OE1 1 
ATOM   4508 N  NE2 . GLN C 1 54  ? -9.07077  -9.85477  -24.49641 1.000 33.98083 ? 52  GLN C NE2 1 
ATOM   4509 N  N   . VAL C 1 55  ? -3.31562  -9.59552  -23.27057 1.000 28.54287 ? 53  VAL C N   1 
ATOM   4510 C  CA  . VAL C 1 55  ? -3.09733  -8.59644  -22.23350 1.000 28.18643 ? 53  VAL C CA  1 
ATOM   4511 C  C   . VAL C 1 55  ? -2.05835  -7.57094  -22.68345 1.000 28.06401 ? 53  VAL C C   1 
ATOM   4512 O  O   . VAL C 1 55  ? -2.24087  -6.37978  -22.47065 1.000 27.94392 ? 53  VAL C O   1 
ATOM   4513 C  CB  . VAL C 1 55  ? -2.73415  -9.26991  -20.89191 1.000 27.57224 ? 53  VAL C CB  1 
ATOM   4514 C  CG1 . VAL C 1 55  ? -2.15392  -8.27895  -19.91131 1.000 29.11132 ? 53  VAL C CG1 1 
ATOM   4515 C  CG2 . VAL C 1 55  ? -3.99029  -9.86801  -20.28623 1.000 30.89795 ? 53  VAL C CG2 1 
ATOM   4516 N  N   . THR C 1 56  ? -1.00049  -7.99577  -23.38319 1.000 29.05448 ? 54  THR C N   1 
ATOM   4517 C  CA  . THR C 1 56  ? -0.02179  -7.00387  -23.82134 1.000 28.06521 ? 54  THR C CA  1 
ATOM   4518 C  C   . THR C 1 56  ? -0.64904  -6.01003  -24.79516 1.000 26.85097 ? 54  THR C C   1 
ATOM   4519 O  O   . THR C 1 56  ? -0.35980  -4.81866  -24.72137 1.000 25.67260 ? 54  THR C O   1 
ATOM   4520 C  CB  . THR C 1 56  ? 1.22012   -7.65182  -24.43739 1.000 26.85231 ? 54  THR C CB  1 
ATOM   4521 O  OG1 . THR C 1 56  ? 0.85866   -8.36339  -25.62957 1.000 30.89579 ? 54  THR C OG1 1 
ATOM   4522 C  CG2 . THR C 1 56  ? 1.85064   -8.59514  -23.43555 1.000 26.67828 ? 54  THR C CG2 1 
ATOM   4523 N  N   . HIS C 1 57  ? -1.56269  -6.46209  -25.66417 1.000 27.96345 ? 55  HIS C N   1 
ATOM   4524 C  CA  . HIS C 1 57  ? -2.24960  -5.49526  -26.53057 1.000 29.39868 ? 55  HIS C CA  1 
ATOM   4525 C  C   . HIS C 1 57  ? -3.14287  -4.56632  -25.71741 1.000 27.92421 ? 55  HIS C C   1 
ATOM   4526 O  O   . HIS C 1 57  ? -3.18369  -3.36055  -25.96426 1.000 29.15310 ? 55  HIS C O   1 
ATOM   4527 C  CB  . HIS C 1 57  ? -3.10514  -6.19692  -27.59373 1.000 28.98825 ? 55  HIS C CB  1 
ATOM   4528 C  CG  . HIS C 1 57  ? -2.32353  -6.89009  -28.67531 1.000 30.84947 ? 55  HIS C CG  1 
ATOM   4529 N  ND1 . HIS C 1 57  ? -1.79711  -8.16036  -28.51561 1.000 29.92123 ? 55  HIS C ND1 1 
ATOM   4530 C  CD2 . HIS C 1 57  ? -2.02498  -6.51904  -29.94722 1.000 30.48728 ? 55  HIS C CD2 1 
ATOM   4531 C  CE1 . HIS C 1 57  ? -1.19329  -8.53043  -29.63637 1.000 29.53547 ? 55  HIS C CE1 1 
ATOM   4532 N  NE2 . HIS C 1 57  ? -1.32152  -7.55782  -30.51955 1.000 30.51713 ? 55  HIS C NE2 1 
ATOM   4533 N  N   . LEU C 1 58  ? -3.88178  -5.10814  -24.75062 1.000 28.60930 ? 56  LEU C N   1 
ATOM   4534 C  CA  . LEU C 1 58  ? -4.79406  -4.26671  -23.99134 1.000 31.95242 ? 56  LEU C CA  1 
ATOM   4535 C  C   . LEU C 1 58  ? -4.04566  -3.21751  -23.18409 1.000 28.44326 ? 56  LEU C C   1 
ATOM   4536 O  O   . LEU C 1 58  ? -4.50279  -2.08697  -23.06692 1.000 26.63693 ? 56  LEU C O   1 
ATOM   4537 C  CB  . LEU C 1 58  ? -5.66746  -5.11633  -23.07957 1.000 26.59249 ? 56  LEU C CB  1 
ATOM   4538 C  CG  . LEU C 1 58  ? -6.67395  -6.03047  -23.76539 1.000 30.13959 ? 56  LEU C CG  1 
ATOM   4539 C  CD1 . LEU C 1 58  ? -7.53842  -6.68010  -22.68922 1.000 27.91378 ? 56  LEU C CD1 1 
ATOM   4540 C  CD2 . LEU C 1 58  ? -7.52260  -5.28903  -24.76629 1.000 31.39737 ? 56  LEU C CD2 1 
ATOM   4541 N  N   . ILE C 1 59  ? -2.91230  -3.57441  -22.59239 1.000 27.94520 ? 57  ILE C N   1 
ATOM   4542 C  CA  . ILE C 1 59  ? -2.12022  -2.56220  -21.89705 1.000 24.27541 ? 57  ILE C CA  1 
ATOM   4543 C  C   . ILE C 1 59  ? -1.70724  -1.46529  -22.86621 1.000 27.83781 ? 57  ILE C C   1 
ATOM   4544 O  O   . ILE C 1 59  ? -1.77937  -0.27017  -22.55618 1.000 25.67717 ? 57  ILE C O   1 
ATOM   4545 C  CB  . ILE C 1 59  ? -0.90663  -3.23566  -21.22977 1.000 27.31212 ? 57  ILE C CB  1 
ATOM   4546 C  CG1 . ILE C 1 59  ? -1.39507  -4.04178  -20.00369 1.000 27.86509 ? 57  ILE C CG1 1 
ATOM   4547 C  CG2 . ILE C 1 59  ? 0.18796   -2.20366  -20.89116 1.000 25.17784 ? 57  ILE C CG2 1 
ATOM   4548 C  CD1 . ILE C 1 59  ? -0.37758  -5.02103  -19.45653 1.000 28.86016 ? 57  ILE C CD1 1 
ATOM   4549 N  N   . THR C 1 60  ? -1.29706  -1.86043  -24.07168 1.000 27.28686 ? 58  THR C N   1 
ATOM   4550 C  CA  . THR C 1 60  ? -0.85826  -0.88598  -25.06134 1.000 24.92914 ? 58  THR C CA  1 
ATOM   4551 C  C   . THR C 1 60  ? -1.99202  0.04189   -25.44899 1.000 25.97351 ? 58  THR C C   1 
ATOM   4552 O  O   . THR C 1 60  ? -1.81830  1.26287   -25.48462 1.000 26.67415 ? 58  THR C O   1 
ATOM   4553 C  CB  . THR C 1 60  ? -0.32562  -1.60710  -26.30367 1.000 23.70727 ? 58  THR C CB  1 
ATOM   4554 O  OG1 . THR C 1 60  ? 0.71288   -2.52950  -25.92487 1.000 28.20973 ? 58  THR C OG1 1 
ATOM   4555 C  CG2 . THR C 1 60  ? 0.21293   -0.60950  -27.31366 1.000 25.99963 ? 58  THR C CG2 1 
ATOM   4556 N  N   . GLU C 1 61  ? -3.17595  -0.51514  -25.73522 1.000 27.34316 ? 59  GLU C N   1 
ATOM   4557 C  CA  . GLU C 1 61  ? -4.26766  0.37373   -26.15148 1.000 27.70723 ? 59  GLU C CA  1 
ATOM   4558 C  C   . GLU C 1 61  ? -4.75286  1.27108   -25.02107 1.000 26.86639 ? 59  GLU C C   1 
ATOM   4559 O  O   . GLU C 1 61  ? -5.21261  2.39154   -25.28938 1.000 30.55794 ? 59  GLU C O   1 
ATOM   4560 C  CB  . GLU C 1 61  ? -5.42654  -0.43189  -26.72388 1.000 28.83511 ? 59  GLU C CB  1 
ATOM   4561 C  CG  . GLU C 1 61  ? -4.99171  -1.26414  -27.92817 1.000 31.49913 ? 59  GLU C CG  1 
ATOM   4562 C  CD  . GLU C 1 61  ? -5.03668  -0.44713  -29.20935 1.000 30.73706 ? 59  GLU C CD  1 
ATOM   4563 O  OE1 . GLU C 1 61  ? -5.50902  0.70671   -29.13373 1.000 29.68741 ? 59  GLU C OE1 1 
ATOM   4564 O  OE2 . GLU C 1 61  ? -4.58351  -0.93363  -30.27655 1.000 29.13877 ? 59  GLU C OE2 1 
ATOM   4565 N  N   . TYR C 1 62  ? -4.68899  0.82001   -23.76107 1.000 27.42693 ? 60  TYR C N   1 
ATOM   4566 C  CA  . TYR C 1 62  ? -4.98245  1.75156   -22.66804 1.000 26.64072 ? 60  TYR C CA  1 
ATOM   4567 C  C   . TYR C 1 62  ? -3.97570  2.89966   -22.65057 1.000 28.95197 ? 60  TYR C C   1 
ATOM   4568 O  O   . TYR C 1 62  ? -4.35016  4.07365   -22.52050 1.000 27.54283 ? 60  TYR C O   1 
ATOM   4569 C  CB  . TYR C 1 62  ? -4.97145  1.03136   -21.31360 1.000 30.32357 ? 60  TYR C CB  1 
ATOM   4570 C  CG  . TYR C 1 62  ? -6.30367  0.45266   -20.89331 1.000 31.21875 ? 60  TYR C CG  1 
ATOM   4571 C  CD1 . TYR C 1 62  ? -7.50318  0.92581   -21.42822 1.000 36.28221 ? 60  TYR C CD1 1 
ATOM   4572 C  CD2 . TYR C 1 62  ? -6.36479  -0.56958  -19.95998 1.000 30.86306 ? 60  TYR C CD2 1 
ATOM   4573 C  CE1 . TYR C 1 62  ? -8.73672  0.38807   -21.03848 1.000 36.90354 ? 60  TYR C CE1 1 
ATOM   4574 C  CE2 . TYR C 1 62  ? -7.56996  -1.09724  -19.56668 1.000 37.72859 ? 60  TYR C CE2 1 
ATOM   4575 C  CZ  . TYR C 1 62  ? -8.75698  -0.62447  -20.10403 1.000 39.36409 ? 60  TYR C CZ  1 
ATOM   4576 O  OH  . TYR C 1 62  ? -9.94335  -1.21532  -19.69424 1.000 40.21689 ? 60  TYR C OH  1 
ATOM   4577 N  N   . ALA C 1 63  ? -2.68213  2.57401   -22.78174 1.000 26.67058 ? 61  ALA C N   1 
ATOM   4578 C  CA  . ALA C 1 63  ? -1.65742  3.61525   -22.76143 1.000 28.69786 ? 61  ALA C CA  1 
ATOM   4579 C  C   . ALA C 1 63  ? -1.85365  4.60352   -23.91145 1.000 24.99633 ? 61  ALA C C   1 
ATOM   4580 O  O   . ALA C 1 63  ? -1.78109  5.81404   -23.70558 1.000 25.21716 ? 61  ALA C O   1 
ATOM   4581 C  CB  . ALA C 1 63  ? -0.26256  2.98177   -22.80505 1.000 23.57918 ? 61  ALA C CB  1 
ATOM   4582 N  N   . TRP C 1 64  ? -2.18439  4.10763   -25.11144 1.000 27.42616 ? 62  TRP C N   1 
ATOM   4583 C  CA  . TRP C 1 64  ? -2.32630  4.99711   -26.26356 1.000 27.21753 ? 62  TRP C CA  1 
ATOM   4584 C  C   . TRP C 1 64  ? -3.57536  5.87868   -26.14877 1.000 28.49259 ? 62  TRP C C   1 
ATOM   4585 O  O   . TRP C 1 64  ? -3.55829  7.04375   -26.57465 1.000 28.05467 ? 62  TRP C O   1 
ATOM   4586 C  CB  . TRP C 1 64  ? -2.37154  4.17846   -27.55663 1.000 26.86070 ? 62  TRP C CB  1 
ATOM   4587 C  CG  . TRP C 1 64  ? -1.02739  3.84228   -28.10708 1.000 28.21109 ? 62  TRP C CG  1 
ATOM   4588 C  CD1 . TRP C 1 64  ? 0.15434   4.47119   -27.82232 1.000 30.98686 ? 62  TRP C CD1 1 
ATOM   4589 C  CD2 . TRP C 1 64  ? -0.71132  2.78632   -29.01810 1.000 27.43457 ? 62  TRP C CD2 1 
ATOM   4590 N  NE1 . TRP C 1 64  ? 1.18643   3.87781   -28.51927 1.000 30.90111 ? 62  TRP C NE1 1 
ATOM   4591 C  CE2 . TRP C 1 64  ? 0.68340   2.84395   -29.26070 1.000 28.21459 ? 62  TRP C CE2 1 
ATOM   4592 C  CE3 . TRP C 1 64  ? -1.46988  1.79821   -29.66271 1.000 29.42001 ? 62  TRP C CE3 1 
ATOM   4593 C  CZ2 . TRP C 1 64  ? 1.33805   1.95300   -30.13006 1.000 27.22505 ? 62  TRP C CZ2 1 
ATOM   4594 C  CZ3 . TRP C 1 64  ? -0.81631  0.90144   -30.51251 1.000 30.99201 ? 62  TRP C CZ3 1 
ATOM   4595 C  CH2 . TRP C 1 64  ? 0.57281   0.99638   -30.74167 1.000 32.18606 ? 62  TRP C CH2 1 
ATOM   4596 N  N   . VAL C 1 65  ? -4.67737  5.35565   -25.58719 1.000 30.77174 ? 63  VAL C N   1 
ATOM   4597 C  CA  . VAL C 1 65  ? -5.82849  6.24986   -25.48007 1.000 33.33029 ? 63  VAL C CA  1 
ATOM   4598 C  C   . VAL C 1 65  ? -5.53997  7.35068   -24.46179 1.000 29.73218 ? 63  VAL C C   1 
ATOM   4599 O  O   . VAL C 1 65  ? -6.07654  8.45776   -24.56271 1.000 31.15359 ? 63  VAL C O   1 
ATOM   4600 C  CB  . VAL C 1 65  ? -7.13333  5.48717   -25.16139 1.000 34.98204 ? 63  VAL C CB  1 
ATOM   4601 C  CG1 . VAL C 1 65  ? -7.13474  4.92291   -23.73266 1.000 31.16731 ? 63  VAL C CG1 1 
ATOM   4602 C  CG2 . VAL C 1 65  ? -8.34898  6.44207   -25.34260 1.000 34.42160 ? 63  VAL C CG2 1 
ATOM   4603 N  N   . GLN C 1 66  ? -4.69330  7.07230   -23.47041 1.000 29.78590 ? 64  GLN C N   1 
ATOM   4604 C  CA  . GLN C 1 66  ? -4.30424  8.10634   -22.52828 1.000 30.77609 ? 64  GLN C CA  1 
ATOM   4605 C  C   . GLN C 1 66  ? -3.32001  9.07919   -23.18199 1.000 30.52115 ? 64  GLN C C   1 
ATOM   4606 O  O   . GLN C 1 66  ? -3.41341  10.29856  -22.96261 1.000 29.67489 ? 64  GLN C O   1 
ATOM   4607 C  CB  . GLN C 1 66  ? -3.73572  7.47576   -21.25013 1.000 27.09138 ? 64  GLN C CB  1 
ATOM   4608 C  CG  . GLN C 1 66  ? -3.71019  8.42650   -20.03234 1.000 28.86227 ? 64  GLN C CG  1 
ATOM   4609 C  CD  . GLN C 1 66  ? -5.06005  9.07163   -19.76799 1.000 31.71882 ? 64  GLN C CD  1 
ATOM   4610 O  OE1 . GLN C 1 66  ? -6.08299  8.40472   -19.83245 1.000 32.88280 ? 64  GLN C OE1 1 
ATOM   4611 N  NE2 . GLN C 1 66  ? -5.06509  10.38353  -19.45984 1.000 31.32106 ? 64  GLN C NE2 1 
ATOM   4612 N  N   . VAL C 1 67  ? -2.41773  8.58560   -24.04578 1.000 27.57553 ? 65  VAL C N   1 
ATOM   4613 C  CA  . VAL C 1 67  ? -1.59492  9.51821   -24.83419 1.000 28.94738 ? 65  VAL C CA  1 
ATOM   4614 C  C   . VAL C 1 67  ? -2.49676  10.48098  -25.60170 1.000 26.77663 ? 65  VAL C C   1 
ATOM   4615 O  O   . VAL C 1 67  ? -2.27794  11.68343  -25.60313 1.000 25.92689 ? 65  VAL C O   1 
ATOM   4616 C  CB  . VAL C 1 67  ? -0.63818  8.76433   -25.78134 1.000 29.48546 ? 65  VAL C CB  1 
ATOM   4617 C  CG1 . VAL C 1 67  ? 0.02484   9.74547   -26.81946 1.000 28.27287 ? 65  VAL C CG1 1 
ATOM   4618 C  CG2 . VAL C 1 67  ? 0.44910   8.03487   -24.99882 1.000 26.53204 ? 65  VAL C CG2 1 
ATOM   4619 N  N   . HIS C 1 68  ? -3.54408  9.95704   -26.23873 1.000 29.39590 ? 66  HIS C N   1 
ATOM   4620 C  CA  . HIS C 1 68  ? -4.42068  10.78886  -27.06037 1.000 30.44683 ? 66  HIS C CA  1 
ATOM   4621 C  C   . HIS C 1 68  ? -5.10336  11.86088  -26.21377 1.000 30.75005 ? 66  HIS C C   1 
ATOM   4622 O  O   . HIS C 1 68  ? -5.14391  13.03886  -26.57982 1.000 29.83369 ? 66  HIS C O   1 
ATOM   4623 C  CB  . HIS C 1 68  ? -5.46434  9.88881   -27.72527 1.000 31.10654 ? 66  HIS C CB  1 
ATOM   4624 C  CG  . HIS C 1 68  ? -6.29127  10.56862  -28.76566 1.000 32.69473 ? 66  HIS C CG  1 
ATOM   4625 N  ND1 . HIS C 1 68  ? -7.44184  11.27355  -28.47139 1.000 32.57799 ? 66  HIS C ND1 1 
ATOM   4626 C  CD2 . HIS C 1 68  ? -6.13612  10.63996  -30.11180 1.000 31.77682 ? 66  HIS C CD2 1 
ATOM   4627 C  CE1 . HIS C 1 68  ? -7.95166  11.76063  -29.59145 1.000 34.37974 ? 66  HIS C CE1 1 
ATOM   4628 N  NE2 . HIS C 1 68  ? -7.19195  11.36818  -30.60351 1.000 33.29364 ? 66  HIS C NE2 1 
ATOM   4629 N  N   . TYR C 1 69  ? -5.64870  11.44835  -25.06762 1.000 30.86373 ? 67  TYR C N   1 
ATOM   4630 C  CA  . TYR C 1 69  ? -6.27657  12.36518  -24.13854 1.000 27.65471 ? 67  TYR C CA  1 
ATOM   4631 C  C   . TYR C 1 69  ? -5.32594  13.47279  -23.73228 1.000 29.99076 ? 67  TYR C C   1 
ATOM   4632 O  O   . TYR C 1 69  ? -5.70516  14.64712  -23.71980 1.000 28.44197 ? 67  TYR C O   1 
ATOM   4633 C  CB  . TYR C 1 69  ? -6.73170  11.58716  -22.91361 1.000 30.23685 ? 67  TYR C CB  1 
ATOM   4634 C  CG  . TYR C 1 69  ? -7.62398  12.33094  -21.97415 1.000 30.49835 ? 67  TYR C CG  1 
ATOM   4635 C  CD1 . TYR C 1 69  ? -9.00729  12.27134  -22.12278 1.000 33.95509 ? 67  TYR C CD1 1 
ATOM   4636 C  CD2 . TYR C 1 69  ? -7.10103  13.00850  -20.88756 1.000 29.44593 ? 67  TYR C CD2 1 
ATOM   4637 C  CE1 . TYR C 1 69  ? -9.85127  12.89663  -21.23017 1.000 34.52692 ? 67  TYR C CE1 1 
ATOM   4638 C  CE2 . TYR C 1 69  ? -7.94972  13.65720  -19.96373 1.000 29.77861 ? 67  TYR C CE2 1 
ATOM   4639 C  CZ  . TYR C 1 69  ? -9.31876  13.59090  -20.15536 1.000 34.42604 ? 67  TYR C CZ  1 
ATOM   4640 O  OH  . TYR C 1 69  ? -10.17917 14.19456  -19.26854 1.000 35.49967 ? 67  TYR C OH  1 
ATOM   4641 N  N   . GLU C 1 70  ? -4.07482  13.13357  -23.41260 1.000 27.58222 ? 68  GLU C N   1 
ATOM   4642 C  CA  . GLU C 1 70  ? -3.19973  14.20245  -22.94520 1.000 28.19602 ? 68  GLU C CA  1 
ATOM   4643 C  C   . GLU C 1 70  ? -2.70279  15.08388  -24.08555 1.000 31.08638 ? 68  GLU C C   1 
ATOM   4644 O  O   . GLU C 1 70  ? -2.35237  16.24292  -23.84306 1.000 28.69670 ? 68  GLU C O   1 
ATOM   4645 C  CB  . GLU C 1 70  ? -2.02198  13.67196  -22.12164 1.000 27.10152 ? 68  GLU C CB  1 
ATOM   4646 C  CG  . GLU C 1 70  ? -2.32883  12.61329  -21.09268 1.000 27.71215 ? 68  GLU C CG  1 
ATOM   4647 C  CD  . GLU C 1 70  ? -3.06095  13.18249  -19.86774 1.000 33.41693 ? 68  GLU C CD  1 
ATOM   4648 O  OE1 . GLU C 1 70  ? -3.29290  12.42992  -18.88697 1.000 31.45141 ? 68  GLU C OE1 1 
ATOM   4649 O  OE2 . GLU C 1 70  ? -3.48803  14.35794  -19.91697 1.000 33.80809 ? 68  GLU C OE2 1 
ATOM   4650 N  N   . LEU C 1 71  ? -2.65772  14.56020  -25.31500 1.000 29.65065 ? 69  LEU C N   1 
ATOM   4651 C  CA  . LEU C 1 71  ? -2.26763  15.40062  -26.44419 1.000 29.19357 ? 69  LEU C CA  1 
ATOM   4652 C  C   . LEU C 1 71  ? -3.36174  16.40202  -26.79542 1.000 30.49052 ? 69  LEU C C   1 
ATOM   4653 O  O   . LEU C 1 71  ? -3.06218  17.55386  -27.13936 1.000 33.43667 ? 69  LEU C O   1 
ATOM   4654 C  CB  . LEU C 1 71  ? -1.91790  14.52441  -27.64548 1.000 25.32916 ? 69  LEU C CB  1 
ATOM   4655 C  CG  . LEU C 1 71  ? -0.60489  13.72590  -27.50001 1.000 27.92877 ? 69  LEU C CG  1 
ATOM   4656 C  CD1 . LEU C 1 71  ? -0.34653  12.88642  -28.76138 1.000 24.81141 ? 69  LEU C CD1 1 
ATOM   4657 C  CD2 . LEU C 1 71  ? 0.57282   14.63038  -27.22735 1.000 31.58986 ? 69  LEU C CD2 1 
ATOM   4658 N  N   . ARG C 1 72  ? -4.63256  15.99290  -26.71420 1.000 29.83711 ? 70  ARG C N   1 
ATOM   4659 C  CA  . ARG C 1 72  ? -5.73003  16.96760  -26.79664 1.000 35.30926 ? 70  ARG C CA  1 
ATOM   4660 C  C   . ARG C 1 72  ? -5.57109  18.09607  -25.77844 1.000 34.08478 ? 70  ARG C C   1 
ATOM   4661 O  O   . ARG C 1 72  ? -5.78215  19.27208  -26.10098 1.000 29.38534 ? 70  ARG C O   1 
ATOM   4662 C  CB  . ARG C 1 72  ? -7.06998  16.26404  -26.58682 1.000 34.12231 ? 70  ARG C CB  1 
ATOM   4663 C  CG  . ARG C 1 72  ? -7.49430  15.46006  -27.80375 1.000 36.07099 ? 70  ARG C CG  1 
ATOM   4664 C  CD  . ARG C 1 72  ? -8.63129  14.54089  -27.45018 1.000 36.54957 ? 70  ARG C CD  1 
ATOM   4665 N  NE  . ARG C 1 72  ? -9.74011  15.26985  -26.84720 1.000 39.71253 ? 70  ARG C NE  1 
ATOM   4666 C  CZ  . ARG C 1 72  ? -10.58496 14.75691  -25.96312 1.000 42.83336 ? 70  ARG C CZ  1 
ATOM   4667 N  NH1 . ARG C 1 72  ? -10.47307 13.50244  -25.54255 1.000 38.96933 ? 70  ARG C NH1 1 
ATOM   4668 N  NH2 . ARG C 1 72  ? -11.56654 15.52119  -25.48788 1.000 42.99356 ? 70  ARG C NH2 1 
ATOM   4669 N  N   . ARG C 1 73  ? -5.22748  17.75977  -24.53339 1.000 30.92261 ? 71  ARG C N   1 
ATOM   4670 C  CA  . ARG C 1 73  ? -4.98968  18.81112  -23.54817 1.000 31.09179 ? 71  ARG C CA  1 
ATOM   4671 C  C   . ARG C 1 73  ? -3.81530  19.69734  -23.95262 1.000 34.12358 ? 71  ARG C C   1 
ATOM   4672 O  O   . ARG C 1 73  ? -3.80615  20.91167  -23.66936 1.000 30.50292 ? 71  ARG C O   1 
ATOM   4673 C  CB  . ARG C 1 73  ? -4.71722  18.20176  -22.18014 1.000 31.45587 ? 71  ARG C CB  1 
ATOM   4674 C  CG  . ARG C 1 73  ? -5.96225  17.81352  -21.41899 1.000 33.60849 ? 71  ARG C CG  1 
ATOM   4675 C  CD  . ARG C 1 73  ? -5.58182  16.96256  -20.24069 1.000 32.34316 ? 71  ARG C CD  1 
ATOM   4676 N  NE  . ARG C 1 73  ? -5.23431  17.76997  -19.07836 1.000 30.36629 ? 71  ARG C NE  1 
ATOM   4677 C  CZ  . ARG C 1 73  ? -4.72676  17.25697  -17.96745 1.000 32.50224 ? 71  ARG C CZ  1 
ATOM   4678 N  NH1 . ARG C 1 73  ? -4.43918  15.96838  -17.87662 1.000 30.55432 ? 71  ARG C NH1 1 
ATOM   4679 N  NH2 . ARG C 1 73  ? -4.52931  18.04639  -16.91247 1.000 31.00193 ? 71  ARG C NH2 1 
ATOM   4680 N  N   . ALA C 1 74  ? -2.79214  19.09737  -24.56786 1.000 30.47235 ? 72  ALA C N   1 
ATOM   4681 C  CA  . ALA C 1 74  ? -1.64650  19.88060  -25.00265 1.000 31.02010 ? 72  ALA C CA  1 
ATOM   4682 C  C   . ALA C 1 74  ? -2.06086  20.85549  -26.09325 1.000 32.78018 ? 72  ALA C C   1 
ATOM   4683 O  O   . ALA C 1 74  ? -1.65887  22.02476  -26.07418 1.000 30.20683 ? 72  ALA C O   1 
ATOM   4684 C  CB  . ALA C 1 74  ? -0.52195  18.95502  -25.47912 1.000 31.01739 ? 72  ALA C CB  1 
ATOM   4685 N  N   . ILE C 1 75  ? -2.93218  20.41720  -27.00253 1.000 31.32123 ? 73  ILE C N   1 
ATOM   4686 C  CA  . ILE C 1 75  ? -3.45319  21.33625  -28.01077 1.000 33.59140 ? 73  ILE C CA  1 
ATOM   4687 C  C   . ILE C 1 75  ? -4.14800  22.51566  -27.33912 1.000 31.61353 ? 73  ILE C C   1 
ATOM   4688 O  O   . ILE C 1 75  ? -3.90498  23.67783  -27.67984 1.000 33.73627 ? 73  ILE C O   1 
ATOM   4689 C  CB  . ILE C 1 75  ? -4.39684  20.60378  -28.98496 1.000 33.60198 ? 73  ILE C CB  1 
ATOM   4690 C  CG1 . ILE C 1 75  ? -3.61728  19.60517  -29.84380 1.000 32.14350 ? 73  ILE C CG1 1 
ATOM   4691 C  CG2 . ILE C 1 75  ? -5.14433  21.63302  -29.87588 1.000 34.18320 ? 73  ILE C CG2 1 
ATOM   4692 C  CD1 . ILE C 1 75  ? -4.51097  18.68209  -30.71263 1.000 33.08113 ? 73  ILE C CD1 1 
ATOM   4693 N  N   . GLY C 1 76  ? -4.99272  22.23628  -26.34270 1.000 34.26203 ? 74  GLY C N   1 
ATOM   4694 C  CA  . GLY C 1 76  ? -5.69404  23.31267  -25.65958 1.000 27.33128 ? 74  GLY C CA  1 
ATOM   4695 C  C   . GLY C 1 76  ? -4.74723  24.29880  -25.00523 1.000 33.83435 ? 74  GLY C C   1 
ATOM   4696 O  O   . GLY C 1 76  ? -4.91710  25.52573  -25.12085 1.000 34.11751 ? 74  GLY C O   1 
ATOM   4697 N  N   . HIS C 1 77  ? -3.73063  23.77974  -24.30757 1.000 32.86590 ? 75  HIS C N   1 
ATOM   4698 C  CA  . HIS C 1 77  ? -2.73386  24.64502  -23.67126 1.000 30.72023 ? 75  HIS C CA  1 
ATOM   4699 C  C   . HIS C 1 77  ? -2.00184  25.50817  -24.70982 1.000 32.52637 ? 75  HIS C C   1 
ATOM   4700 O  O   . HIS C 1 77  ? -1.84441  26.72844  -24.53825 1.000 35.21626 ? 75  HIS C O   1 
ATOM   4701 C  CB  . HIS C 1 77  ? -1.73584  23.79042  -22.88150 1.000 31.66541 ? 75  HIS C CB  1 
ATOM   4702 C  CG  . HIS C 1 77  ? -2.30043  23.16825  -21.63314 1.000 33.74297 ? 75  HIS C CG  1 
ATOM   4703 N  ND1 . HIS C 1 77  ? -3.04257  23.87786  -20.71601 1.000 36.37824 ? 75  HIS C ND1 1 
ATOM   4704 C  CD2 . HIS C 1 77  ? -2.20819  21.90679  -21.14290 1.000 33.26040 ? 75  HIS C CD2 1 
ATOM   4705 C  CE1 . HIS C 1 77  ? -3.38998  23.08202  -19.71717 1.000 33.38648 ? 75  HIS C CE1 1 
ATOM   4706 N  NE2 . HIS C 1 77  ? -2.89426  21.88190  -19.95200 1.000 33.48089 ? 75  HIS C NE2 1 
ATOM   4707 N  N   . LEU C 1 78  ? -1.56438  24.88944  -25.80670 1.000 31.97286 ? 76  LEU C N   1 
ATOM   4708 C  CA  . LEU C 1 78  ? -0.75414  25.60238  -26.78644 1.000 34.19899 ? 76  LEU C CA  1 
ATOM   4709 C  C   . LEU C 1 78  ? -1.55192  26.70208  -27.47027 1.000 32.73896 ? 76  LEU C C   1 
ATOM   4710 O  O   . LEU C 1 78  ? -1.01925  27.78736  -27.73874 1.000 34.34292 ? 76  LEU C O   1 
ATOM   4711 C  CB  . LEU C 1 78  ? -0.20480  24.60259  -27.80975 1.000 32.92640 ? 76  LEU C CB  1 
ATOM   4712 C  CG  . LEU C 1 78  ? 0.99132   23.80157  -27.29057 1.000 27.91371 ? 76  LEU C CG  1 
ATOM   4713 C  CD1 . LEU C 1 78  ? 1.36662   22.71172  -28.30474 1.000 29.33072 ? 76  LEU C CD1 1 
ATOM   4714 C  CD2 . LEU C 1 78  ? 2.19324   24.68272  -27.02164 1.000 26.60903 ? 76  LEU C CD2 1 
ATOM   4715 N  N   . ASP C 1 79  ? -2.82537  26.43788  -27.76738 1.000 33.08747 ? 77  ASP C N   1 
ATOM   4716 C  CA  . ASP C 1 79  ? -3.67942  27.43480  -28.40172 1.000 33.71990 ? 77  ASP C CA  1 
ATOM   4717 C  C   . ASP C 1 79  ? -3.89573  28.64891  -27.51468 1.000 39.09519 ? 77  ASP C C   1 
ATOM   4718 O  O   . ASP C 1 79  ? -4.23586  29.72583  -28.02334 1.000 33.50484 ? 77  ASP C O   1 
ATOM   4719 C  CB  . ASP C 1 79  ? -5.02741  26.81061  -28.78247 1.000 32.47004 ? 77  ASP C CB  1 
ATOM   4720 C  CG  . ASP C 1 79  ? -4.95417  25.98895  -30.04956 1.000 37.20036 ? 77  ASP C CG  1 
ATOM   4721 O  OD1 . ASP C 1 79  ? -3.89621  26.01528  -30.71585 1.000 35.18886 ? 77  ASP C OD1 1 
ATOM   4722 O  OD2 . ASP C 1 79  ? -5.95271  25.30911  -30.38645 1.000 41.03750 ? 77  ASP C OD2 1 
ATOM   4723 N  N   . GLU C 1 80  ? -3.71252  28.50001  -26.20199 1.000 36.55230 ? 78  GLU C N   1 
ATOM   4724 C  CA  . GLU C 1 80  ? -3.83978  29.59853  -25.26051 1.000 37.55474 ? 78  GLU C CA  1 
ATOM   4725 C  C   . GLU C 1 80  ? -2.49355  30.05898  -24.70707 1.000 35.39329 ? 78  GLU C C   1 
ATOM   4726 O  O   . GLU C 1 80  ? -2.47007  30.74845  -23.68436 1.000 35.16831 ? 78  GLU C O   1 
ATOM   4727 C  CB  . GLU C 1 80  ? -4.75398  29.18578  -24.10875 1.000 38.46681 ? 78  GLU C CB  1 
ATOM   4728 C  CG  . GLU C 1 80  ? -6.17532  28.82073  -24.53415 1.000 43.54233 ? 78  GLU C CG  1 
ATOM   4729 C  CD  . GLU C 1 80  ? -6.91740  29.93657  -25.27087 1.000 48.87584 ? 78  GLU C CD  1 
ATOM   4730 O  OE1 . GLU C 1 80  ? -6.69963  31.13645  -24.97713 1.000 44.28147 ? 78  GLU C OE1 1 
ATOM   4731 O  OE2 . GLU C 1 80  ? -7.71938  29.59032  -26.16957 1.000 57.50719 ? 78  GLU C OE2 1 
ATOM   4732 N  N   . ASP C 1 81  ? -1.37584  29.65995  -25.33155 1.000 34.90466 ? 79  ASP C N   1 
ATOM   4733 C  CA  . ASP C 1 81  ? -0.02535  30.08313  -24.92217 1.000 33.11600 ? 79  ASP C CA  1 
ATOM   4734 C  C   . ASP C 1 81  ? 0.31369   29.65015  -23.49094 1.000 35.33210 ? 79  ASP C C   1 
ATOM   4735 O  O   . ASP C 1 81  ? 1.13759   30.26974  -22.80964 1.000 31.41646 ? 79  ASP C O   1 
ATOM   4736 C  CB  . ASP C 1 81  ? 0.13754   31.60118  -25.08460 1.000 36.04701 ? 79  ASP C CB  1 
ATOM   4737 C  CG  . ASP C 1 81  ? -0.14441  32.05669  -26.50439 1.000 36.02964 ? 79  ASP C CG  1 
ATOM   4738 O  OD1 . ASP C 1 81  ? 0.26532   31.36964  -27.46048 1.000 37.80705 ? 79  ASP C OD1 1 
ATOM   4739 O  OD2 . ASP C 1 81  ? -0.83998  33.06172  -26.67201 1.000 39.90473 ? 79  ASP C OD2 1 
ATOM   4740 N  N   . ARG C 1 82  ? -0.28716  28.56166  -23.00659 1.000 35.00730 ? 80  ARG C N   1 
ATOM   4741 C  CA  . ARG C 1 82  ? 0.08139   28.06043  -21.68307 1.000 35.40425 ? 80  ARG C CA  1 
ATOM   4742 C  C   . ARG C 1 82  ? 1.20849   27.04340  -21.86980 1.000 31.77848 ? 80  ARG C C   1 
ATOM   4743 O  O   . ARG C 1 82  ? 1.01140   25.82241  -21.85259 1.000 32.60637 ? 80  ARG C O   1 
ATOM   4744 C  CB  . ARG C 1 82  ? -1.13624  27.49196  -20.95444 1.000 34.93241 ? 80  ARG C CB  1 
ATOM   4745 C  CG  . ARG C 1 82  ? -2.34778  28.46336  -20.86901 1.000 36.60577 ? 80  ARG C CG  1 
ATOM   4746 C  CD  . ARG C 1 82  ? -3.51051  27.88854  -20.01391 1.000 38.11521 ? 80  ARG C CD  1 
ATOM   4747 N  NE  . ARG C 1 82  ? -4.10641  26.69690  -20.61294 1.000 36.61345 ? 80  ARG C NE  1 
ATOM   4748 C  CZ  . ARG C 1 82  ? -5.31203  26.62023  -21.17263 1.000 39.35983 ? 80  ARG C CZ  1 
ATOM   4749 N  NH1 . ARG C 1 82  ? -6.11827  27.67318  -21.25344 1.000 35.60895 ? 80  ARG C NH1 1 
ATOM   4750 N  NH2 . ARG C 1 82  ? -5.72384  25.44784  -21.66420 1.000 41.21206 ? 80  ARG C NH2 1 
ATOM   4751 N  N   . TYR C 1 83  ? 2.43107   27.56827  -22.01951 1.000 29.98794 ? 81  TYR C N   1 
ATOM   4752 C  CA  . TYR C 1 83  ? 3.54652   26.71439  -22.45054 1.000 33.29252 ? 81  TYR C CA  1 
ATOM   4753 C  C   . TYR C 1 83  ? 3.94487   25.70418  -21.37771 1.000 32.93395 ? 81  TYR C C   1 
ATOM   4754 O  O   . TYR C 1 83  ? 4.14754   24.52194  -21.67474 1.000 30.19271 ? 81  TYR C O   1 
ATOM   4755 C  CB  . TYR C 1 83  ? 4.76950   27.54651  -22.83823 1.000 31.25589 ? 81  TYR C CB  1 
ATOM   4756 C  CG  . TYR C 1 83  ? 4.51564   28.72685  -23.73785 1.000 31.62321 ? 81  TYR C CG  1 
ATOM   4757 C  CD1 . TYR C 1 83  ? 3.79060   28.59878  -24.90538 1.000 31.58565 ? 81  TYR C CD1 1 
ATOM   4758 C  CD2 . TYR C 1 83  ? 5.05755   29.98424  -23.43158 1.000 36.21618 ? 81  TYR C CD2 1 
ATOM   4759 C  CE1 . TYR C 1 83  ? 3.59237   29.71185  -25.75049 1.000 30.37334 ? 81  TYR C CE1 1 
ATOM   4760 C  CE2 . TYR C 1 83  ? 4.85014   31.06767  -24.24126 1.000 36.02357 ? 81  TYR C CE2 1 
ATOM   4761 C  CZ  . TYR C 1 83  ? 4.13054   30.92267  -25.40954 1.000 34.77868 ? 81  TYR C CZ  1 
ATOM   4762 O  OH  . TYR C 1 83  ? 3.93741   32.02050  -26.22625 1.000 37.37699 ? 81  TYR C OH  1 
ATOM   4763 N  N   . HIS C 1 84  ? 4.14298   26.16635  -20.14524 1.000 31.82897 ? 82  HIS C N   1 
ATOM   4764 C  CA  . HIS C 1 84  ? 4.52599   25.25794  -19.06612 1.000 32.23676 ? 82  HIS C CA  1 
ATOM   4765 C  C   . HIS C 1 84  ? 3.53846   24.11815  -18.93214 1.000 32.21398 ? 82  HIS C C   1 
ATOM   4766 O  O   . HIS C 1 84  ? 3.91908   22.97550  -18.67287 1.000 28.85409 ? 82  HIS C O   1 
ATOM   4767 C  CB  . HIS C 1 84  ? 4.60573   26.01809  -17.73875 1.000 30.55350 ? 82  HIS C CB  1 
ATOM   4768 C  CG  . HIS C 1 84  ? 5.56135   27.17295  -17.76188 1.000 30.12177 ? 82  HIS C CG  1 
ATOM   4769 N  ND1 . HIS C 1 84  ? 5.24390   28.39351  -18.32009 1.000 34.09895 ? 82  HIS C ND1 1 
ATOM   4770 C  CD2 . HIS C 1 84  ? 6.81249   27.30264  -17.26026 1.000 31.16048 ? 82  HIS C CD2 1 
ATOM   4771 C  CE1 . HIS C 1 84  ? 6.26188   29.22509  -18.16920 1.000 34.19625 ? 82  HIS C CE1 1 
ATOM   4772 N  NE2 . HIS C 1 84  ? 7.23045   28.58404  -17.53606 1.000 37.35676 ? 82  HIS C NE2 1 
ATOM   4773 N  N   . GLN C 1 85  ? 2.25805   24.42752  -19.08212 1.000 28.45511 ? 83  GLN C N   1 
ATOM   4774 C  CA  . GLN C 1 85  ? 1.22061   23.42871  -18.91525 1.000 33.31176 ? 83  GLN C CA  1 
ATOM   4775 C  C   . GLN C 1 85  ? 1.26417   22.39249  -20.03251 1.000 29.37231 ? 83  GLN C C   1 
ATOM   4776 O  O   . GLN C 1 85  ? 1.05467   21.20256  -19.78369 1.000 30.18213 ? 83  GLN C O   1 
ATOM   4777 C  CB  . GLN C 1 85  ? -0.09230  24.19336  -18.84573 1.000 36.86260 ? 83  GLN C CB  1 
ATOM   4778 C  CG  . GLN C 1 85  ? -0.22395  24.86793  -17.47963 1.000 31.90918 ? 83  GLN C CG  1 
ATOM   4779 C  CD  . GLN C 1 85  ? -1.49403  25.67531  -17.33552 1.000 40.15814 ? 83  GLN C CD  1 
ATOM   4780 O  OE1 . GLN C 1 85  ? -1.53832  26.85784  -17.74934 1.000 36.89915 ? 83  GLN C OE1 1 
ATOM   4781 N  NE2 . GLN C 1 85  ? -2.55382  25.03829  -16.84532 1.000 37.33144 ? 83  GLN C NE2 1 
ATOM   4782 N  N   . ALA C 1 86  ? 1.55006   22.82617  -21.26732 1.000 29.97364 ? 84  ALA C N   1 
ATOM   4783 C  CA  . ALA C 1 86  ? 1.69671   21.88886  -22.38358 1.000 28.14295 ? 84  ALA C CA  1 
ATOM   4784 C  C   . ALA C 1 86  ? 2.90084   20.96644  -22.20016 1.000 28.30938 ? 84  ALA C C   1 
ATOM   4785 O  O   . ALA C 1 86  ? 2.84120   19.79630  -22.58649 1.000 29.70390 ? 84  ALA C O   1 
ATOM   4786 C  CB  . ALA C 1 86  ? 1.81950   22.65784  -23.70828 1.000 28.62951 ? 84  ALA C CB  1 
ATOM   4787 N  N   . VAL C 1 87  ? 4.00548   21.46940  -21.63112 1.000 29.34056 ? 85  VAL C N   1 
ATOM   4788 C  CA  . VAL C 1 87  ? 5.19001   20.62810  -21.41132 1.000 29.14296 ? 85  VAL C CA  1 
ATOM   4789 C  C   . VAL C 1 87  ? 4.83280   19.36919  -20.63774 1.000 28.91143 ? 85  VAL C C   1 
ATOM   4790 O  O   . VAL C 1 87  ? 5.27515   18.25792  -20.96707 1.000 29.38477 ? 85  VAL C O   1 
ATOM   4791 C  CB  . VAL C 1 87  ? 6.28478   21.41612  -20.66433 1.000 30.09247 ? 85  VAL C CB  1 
ATOM   4792 C  CG1 . VAL C 1 87  ? 7.43495   20.45985  -20.27328 1.000 31.51486 ? 85  VAL C CG1 1 
ATOM   4793 C  CG2 . VAL C 1 87  ? 6.81876   22.47642  -21.51375 1.000 30.26623 ? 85  VAL C CG2 1 
ATOM   4794 N  N   . ARG C 1 88  ? 4.05532   19.53548  -19.56558 1.000 27.65236 ? 86  ARG C N   1 
ATOM   4795 C  CA  . ARG C 1 88  ? 3.70573   18.41026  -18.72341 1.000 29.06910 ? 86  ARG C CA  1 
ATOM   4796 C  C   . ARG C 1 88  ? 2.90485   17.35865  -19.48208 1.000 27.06826 ? 86  ARG C C   1 
ATOM   4797 O  O   . ARG C 1 88  ? 3.07445   16.15913  -19.24504 1.000 28.73078 ? 86  ARG C O   1 
ATOM   4798 C  CB  . ARG C 1 88  ? 2.91362   18.89191  -17.50813 1.000 25.56696 ? 86  ARG C CB  1 
ATOM   4799 C  CG  . ARG C 1 88  ? 3.66235   19.84164  -16.62168 1.000 27.55883 ? 86  ARG C CG  1 
ATOM   4800 C  CD  . ARG C 1 88  ? 2.95443   19.92863  -15.23826 1.000 28.06411 ? 86  ARG C CD  1 
ATOM   4801 N  NE  . ARG C 1 88  ? 3.61252   20.94555  -14.43654 1.000 27.80887 ? 86  ARG C NE  1 
ATOM   4802 C  CZ  . ARG C 1 88  ? 3.21420   22.20464  -14.37637 1.000 31.16085 ? 86  ARG C CZ  1 
ATOM   4803 N  NH1 . ARG C 1 88  ? 2.14123   22.62189  -15.03089 1.000 30.30199 ? 86  ARG C NH1 1 
ATOM   4804 N  NH2 . ARG C 1 88  ? 3.91655   23.07025  -13.65023 1.000 31.05134 ? 86  ARG C NH2 1 
ATOM   4805 N  N   . MET C 1 89  ? 1.99447   17.78160  -20.36220 1.000 25.96897 ? 87  MET C N   1 
ATOM   4806 C  CA  . MET C 1 89  ? 1.20687   16.80078  -21.10306 1.000 27.70841 ? 87  MET C CA  1 
ATOM   4807 C  C   . MET C 1 89  ? 2.08798   16.01675  -22.06864 1.000 29.09247 ? 87  MET C C   1 
ATOM   4808 O  O   . MET C 1 89  ? 1.89778   14.80434  -22.25365 1.000 29.37624 ? 87  MET C O   1 
ATOM   4809 C  CB  . MET C 1 89  ? 0.06627   17.48256  -21.84806 1.000 29.81767 ? 87  MET C CB  1 
ATOM   4810 C  CG  . MET C 1 89  ? -0.71044  18.36241  -20.92027 1.000 35.27797 ? 87  MET C CG  1 
ATOM   4811 S  SD  . MET C 1 89  ? -1.63319  17.37444  -19.79286 1.000 46.72166 ? 87  MET C SD  1 
ATOM   4812 C  CE  . MET C 1 89  ? -0.85729  17.98700  -18.30477 1.000 36.16991 ? 87  MET C CE  1 
ATOM   4813 N  N   . PHE C 1 90  ? 3.07463   16.67643  -22.67529 1.000 30.08066 ? 88  PHE C N   1 
ATOM   4814 C  CA  . PHE C 1 90  ? 3.95595   15.93132  -23.57088 1.000 26.89656 ? 88  PHE C CA  1 
ATOM   4815 C  C   . PHE C 1 90  ? 4.84089   14.98122  -22.78085 1.000 28.27857 ? 88  PHE C C   1 
ATOM   4816 O  O   . PHE C 1 90  ? 5.04369   13.84131  -23.19595 1.000 27.67071 ? 88  PHE C O   1 
ATOM   4817 C  CB  . PHE C 1 90  ? 4.80867   16.87955  -24.41837 1.000 29.25151 ? 88  PHE C CB  1 
ATOM   4818 C  CG  . PHE C 1 90  ? 4.04915   17.55366  -25.52604 1.000 27.30212 ? 88  PHE C CG  1 
ATOM   4819 C  CD1 . PHE C 1 90  ? 3.46960   16.80289  -26.54667 1.000 28.08828 ? 88  PHE C CD1 1 
ATOM   4820 C  CD2 . PHE C 1 90  ? 3.93443   18.94132  -25.56068 1.000 30.08698 ? 88  PHE C CD2 1 
ATOM   4821 C  CE1 . PHE C 1 90  ? 2.77038   17.42961  -27.57569 1.000 28.44400 ? 88  PHE C CE1 1 
ATOM   4822 C  CE2 . PHE C 1 90  ? 3.23498   19.58252  -26.57750 1.000 28.83571 ? 88  PHE C CE2 1 
ATOM   4823 C  CZ  . PHE C 1 90  ? 2.67249   18.82507  -27.60161 1.000 30.59852 ? 88  PHE C CZ  1 
ATOM   4824 N  N   . ASP C 1 91  ? 5.35889   15.42186  -21.63056 1.000 29.04769 ? 89  ASP C N   1 
ATOM   4825 C  CA  . ASP C 1 91  ? 6.15653   14.52479  -20.79791 1.000 29.77917 ? 89  ASP C CA  1 
ATOM   4826 C  C   . ASP C 1 91  ? 5.33762   13.31319  -20.34569 1.000 30.67818 ? 89  ASP C C   1 
ATOM   4827 O  O   . ASP C 1 91  ? 5.82353   12.17875  -20.37428 1.000 28.75319 ? 89  ASP C O   1 
ATOM   4828 C  CB  . ASP C 1 91  ? 6.68006   15.26673  -19.57900 1.000 30.81439 ? 89  ASP C CB  1 
ATOM   4829 C  CG  . ASP C 1 91  ? 7.89735   16.11103  -19.89016 1.000 34.16403 ? 89  ASP C CG  1 
ATOM   4830 O  OD1 . ASP C 1 91  ? 8.49153   15.91878  -20.97560 1.000 34.02896 ? 89  ASP C OD1 1 
ATOM   4831 O  OD2 . ASP C 1 91  ? 8.24223   16.97485  -19.05704 1.000 33.19017 ? 89  ASP C OD2 1 
ATOM   4832 N  N   . ARG C 1 92  ? 4.10189   13.54289  -19.89869 1.000 29.20165 ? 90  ARG C N   1 
ATOM   4833 C  CA  . ARG C 1 92  ? 3.24623   12.43092  -19.49938 1.000 29.82729 ? 90  ARG C CA  1 
ATOM   4834 C  C   . ARG C 1 92  ? 3.01553   11.48794  -20.66939 1.000 28.99074 ? 90  ARG C C   1 
ATOM   4835 O  O   . ARG C 1 92  ? 3.08182   10.25591  -20.51822 1.000 27.50268 ? 90  ARG C O   1 
ATOM   4836 C  CB  . ARG C 1 92  ? 1.91601   12.95137  -18.96251 1.000 25.80910 ? 90  ARG C CB  1 
ATOM   4837 C  CG  . ARG C 1 92  ? 1.15698   11.96646  -18.11764 1.000 33.60480 ? 90  ARG C CG  1 
ATOM   4838 C  CD  . ARG C 1 92  ? -0.25586  12.48919  -17.86250 1.000 32.31637 ? 90  ARG C CD  1 
ATOM   4839 N  NE  . ARG C 1 92  ? -0.25351  13.61375  -16.93094 1.000 32.97216 ? 90  ARG C NE  1 
ATOM   4840 C  CZ  . ARG C 1 92  ? -1.34593  14.07477  -16.33727 1.000 34.77635 ? 90  ARG C CZ  1 
ATOM   4841 N  NH1 . ARG C 1 92  ? -2.52726  13.53072  -16.56240 1.000 30.71099 ? 90  ARG C NH1 1 
ATOM   4842 N  NH2 . ARG C 1 92  ? -1.25157  15.12175  -15.51130 1.000 35.92238 ? 90  ARG C NH2 1 
ATOM   4843 N  N   . ALA C 1 93  ? 2.73659   12.04557  -21.85396 1.000 23.11831 ? 91  ALA C N   1 
ATOM   4844 C  CA  . ALA C 1 93  ? 2.56699   11.17100  -23.01338 1.000 27.35885 ? 91  ALA C CA  1 
ATOM   4845 C  C   . ALA C 1 93  ? 3.80886   10.32826  -23.24219 1.000 27.29475 ? 91  ALA C C   1 
ATOM   4846 O  O   . ALA C 1 93  ? 3.71157   9.15818   -23.64035 1.000 25.93674 ? 91  ALA C O   1 
ATOM   4847 C  CB  . ALA C 1 93  ? 2.26538   11.97979  -24.26433 1.000 24.20786 ? 91  ALA C CB  1 
ATOM   4848 N  N   . THR C 1 94  ? 4.99215   10.91609  -23.03768 1.000 26.47353 ? 92  THR C N   1 
ATOM   4849 C  CA  . THR C 1 94  ? 6.21645   10.15523  -23.26268 1.000 26.32217 ? 92  THR C CA  1 
ATOM   4850 C  C   . THR C 1 94  ? 6.29676   8.96264   -22.32284 1.000 24.96022 ? 92  THR C C   1 
ATOM   4851 O  O   . THR C 1 94  ? 6.64131   7.86361   -22.74839 1.000 29.05330 ? 92  THR C O   1 
ATOM   4852 C  CB  . THR C 1 94  ? 7.44528   11.04375  -23.10669 1.000 26.41698 ? 92  THR C CB  1 
ATOM   4853 O  OG1 . THR C 1 94  ? 7.39976   12.07643  -24.10048 1.000 28.13943 ? 92  THR C OG1 1 
ATOM   4854 C  CG2 . THR C 1 94  ? 8.73081   10.23715  -23.33942 1.000 26.02235 ? 92  THR C CG2 1 
ATOM   4855 N  N   . GLY C 1 95  ? 5.98679   9.16428   -21.03204 1.000 26.91075 ? 93  GLY C N   1 
ATOM   4856 C  CA  . GLY C 1 95  ? 5.99378   8.04383   -20.10781 1.000 23.82286 ? 93  GLY C CA  1 
ATOM   4857 C  C   . GLY C 1 95  ? 5.01545   6.96251   -20.51809 1.000 26.50327 ? 93  GLY C C   1 
ATOM   4858 O  O   . GLY C 1 95  ? 5.29644   5.77637   -20.37337 1.000 27.28324 ? 93  GLY C O   1 
ATOM   4859 N  N   . LEU C 1 96  ? 3.83201   7.36380   -20.98879 1.000 24.75390 ? 94  LEU C N   1 
ATOM   4860 C  CA  . LEU C 1 96  ? 2.82428   6.39760   -21.41248 1.000 25.43393 ? 94  LEU C CA  1 
ATOM   4861 C  C   . LEU C 1 96  ? 3.28477   5.63945   -22.64952 1.000 26.00526 ? 94  LEU C C   1 
ATOM   4862 O  O   . LEU C 1 96  ? 3.06803   4.42064   -22.76725 1.000 30.48016 ? 94  LEU C O   1 
ATOM   4863 C  CB  . LEU C 1 96  ? 1.50937   7.14152   -21.66681 1.000 28.19577 ? 94  LEU C CB  1 
ATOM   4864 C  CG  . LEU C 1 96  ? 0.75170   7.56731   -20.38759 1.000 28.54249 ? 94  LEU C CG  1 
ATOM   4865 C  CD1 . LEU C 1 96  ? -0.20932  8.73834   -20.69473 1.000 25.46023 ? 94  LEU C CD1 1 
ATOM   4866 C  CD2 . LEU C 1 96  ? -0.01183  6.39946   -19.77830 1.000 29.13433 ? 94  LEU C CD2 1 
ATOM   4867 N  N   . SER C 1 97  ? 3.96231   6.33913   -23.56389 1.000 29.30365 ? 95  SER C N   1 
ATOM   4868 C  CA  . SER C 1 97  ? 4.56062   5.66965   -24.71803 1.000 26.26108 ? 95  SER C CA  1 
ATOM   4869 C  C   . SER C 1 97  ? 5.60223   4.64335   -24.27759 1.000 27.19389 ? 95  SER C C   1 
ATOM   4870 O  O   . SER C 1 97  ? 5.68452   3.54327   -24.83881 1.000 26.57525 ? 95  SER C O   1 
ATOM   4871 C  CB  . SER C 1 97  ? 5.19192   6.70853   -25.65081 1.000 26.64522 ? 95  SER C CB  1 
ATOM   4872 O  OG  . SER C 1 97  ? 5.67625   6.07317   -26.85919 1.000 30.71943 ? 95  SER C OG  1 
ATOM   4873 N  N   . GLU C 1 98  ? 6.39643   4.97800   -23.25701 1.000 28.08422 ? 96  GLU C N   1 
ATOM   4874 C  CA  . GLU C 1 98  ? 7.40130   4.03087   -22.79326 1.000 30.67223 ? 96  GLU C CA  1 
ATOM   4875 C  C   . GLU C 1 98  ? 6.74620   2.77262   -22.23857 1.000 29.99277 ? 96  GLU C C   1 
ATOM   4876 O  O   . GLU C 1 98  ? 7.32977   1.67526   -22.31411 1.000 29.93454 ? 96  GLU C O   1 
ATOM   4877 C  CB  . GLU C 1 98  ? 8.30868   4.69808   -21.75257 1.000 27.94814 ? 96  GLU C CB  1 
ATOM   4878 C  CG  . GLU C 1 98  ? 9.35410   5.65108   -22.36715 1.000 28.89261 ? 96  GLU C CG  1 
ATOM   4879 C  CD  . GLU C 1 98  ? 10.22162  4.98308   -23.45076 1.000 32.39524 ? 96  GLU C CD  1 
ATOM   4880 O  OE1 . GLU C 1 98  ? 11.00170  4.07069   -23.11845 1.000 32.47291 ? 96  GLU C OE1 1 
ATOM   4881 O  OE2 . GLU C 1 98  ? 10.13756  5.37555   -24.63217 1.000 32.92913 ? 96  GLU C OE2 1 
ATOM   4882 N  N   . VAL C 1 99  ? 5.51766   2.89379   -21.71717 1.000 29.35026 ? 97  VAL C N   1 
ATOM   4883 C  CA  . VAL C 1 99  ? 4.81456   1.69195   -21.27309 1.000 29.48122 ? 97  VAL C CA  1 
ATOM   4884 C  C   . VAL C 1 99  ? 4.47054   0.80169   -22.46959 1.000 29.11261 ? 97  VAL C C   1 
ATOM   4885 O  O   . VAL C 1 99  ? 4.59953   -0.42497  -22.39121 1.000 27.30629 ? 97  VAL C O   1 
ATOM   4886 C  CB  . VAL C 1 99  ? 3.56600   2.03405   -20.44926 1.000 29.64863 ? 97  VAL C CB  1 
ATOM   4887 C  CG1 . VAL C 1 99  ? 2.68440   0.78856   -20.30298 1.000 28.21944 ? 97  VAL C CG1 1 
ATOM   4888 C  CG2 . VAL C 1 99  ? 3.95987   2.58878   -19.06394 1.000 28.54204 ? 97  VAL C CG2 1 
ATOM   4889 N  N   . THR C 1 100 ? 4.06297   1.39503   -23.60356 1.000 27.73941 ? 98  THR C N   1 
ATOM   4890 C  CA  . THR C 1 100 ? 3.79561   0.56904   -24.79583 1.000 26.11823 ? 98  THR C CA  1 
ATOM   4891 C  C   . THR C 1 100 ? 5.04704   -0.14198  -25.27489 1.000 26.33138 ? 98  THR C C   1 
ATOM   4892 O  O   . THR C 1 100 ? 4.96385   -1.23557  -25.84759 1.000 26.91385 ? 98  THR C O   1 
ATOM   4893 C  CB  . THR C 1 100 ? 3.25814   1.40628   -25.95543 1.000 30.40678 ? 98  THR C CB  1 
ATOM   4894 O  OG1 . THR C 1 100 ? 4.31771   2.23633   -26.46642 1.000 29.12909 ? 98  THR C OG1 1 
ATOM   4895 C  CG2 . THR C 1 100 ? 2.05176   2.29328   -25.51716 1.000 27.76650 ? 98  THR C CG2 1 
ATOM   4896 N  N   . VAL C 1 101 ? 6.21013   0.50296   -25.13419 1.000 27.40768 ? 99  VAL C N   1 
ATOM   4897 C  CA  . VAL C 1 101 ? 7.46362   -0.12549  -25.55414 1.000 25.91882 ? 99  VAL C CA  1 
ATOM   4898 C  C   . VAL C 1 101 ? 7.73495   -1.34710  -24.69381 1.000 29.27412 ? 99  VAL C C   1 
ATOM   4899 O  O   . VAL C 1 101 ? 7.99505   -2.43652  -25.20330 1.000 27.93660 ? 99  VAL C O   1 
ATOM   4900 C  CB  . VAL C 1 101 ? 8.63247   0.88704   -25.49112 1.000 30.58255 ? 99  VAL C CB  1 
ATOM   4901 C  CG1 . VAL C 1 101 ? 9.98438   0.19391   -25.77210 1.000 31.52291 ? 99  VAL C CG1 1 
ATOM   4902 C  CG2 . VAL C 1 101 ? 8.39437   2.03215   -26.45995 1.000 28.85388 ? 99  VAL C CG2 1 
ATOM   4903 N  N   . GLN C 1 102 ? 7.59985   -1.20505  -23.36800 1.000 26.47176 ? 100 GLN C N   1 
ATOM   4904 C  CA  . GLN C 1 102 ? 7.85620   -2.35126  -22.50656 1.000 29.08925 ? 100 GLN C CA  1 
ATOM   4905 C  C   . GLN C 1 102 ? 6.84717   -3.47315  -22.77458 1.000 29.63955 ? 100 GLN C C   1 
ATOM   4906 O  O   . GLN C 1 102 ? 7.19612   -4.66038  -22.69832 1.000 28.66530 ? 100 GLN C O   1 
ATOM   4907 C  CB  . GLN C 1 102 ? 7.87274   -1.89188  -21.02424 1.000 34.47642 ? 100 GLN C CB  1 
ATOM   4908 C  CG  . GLN C 1 102 ? 9.18503   -2.40301  -20.31381 1.000 47.67934 ? 100 GLN C CG  1 
ATOM   4909 C  CD  . GLN C 1 102 ? 9.31659   -2.30789  -18.75497 1.000 49.86399 ? 100 GLN C CD  1 
ATOM   4910 O  OE1 . GLN C 1 102 ? 8.34092   -2.25975  -17.97887 1.000 38.24620 ? 100 GLN C OE1 1 
ATOM   4911 N  NE2 . GLN C 1 102 ? 10.58648  -2.31940  -18.30564 1.000 53.18315 ? 100 GLN C NE2 1 
ATOM   4912 N  N   . ALA C 1 103 ? 5.61979   -3.12775  -23.16711 1.000 27.75710 ? 101 ALA C N   1 
ATOM   4913 C  CA  . ALA C 1 103 ? 4.61912   -4.15464  -23.45556 1.000 24.74720 ? 101 ALA C CA  1 
ATOM   4914 C  C   . ALA C 1 103 ? 4.96690   -4.94381  -24.71635 1.000 27.89900 ? 101 ALA C C   1 
ATOM   4915 O  O   . ALA C 1 103 ? 4.84635   -6.17818  -24.73621 1.000 29.09854 ? 101 ALA C O   1 
ATOM   4916 C  CB  . ALA C 1 103 ? 3.22542   -3.50991  -23.58419 1.000 27.06682 ? 101 ALA C CB  1 
ATOM   4917 N  N   . VAL C 1 104 ? 5.40349   -4.27410  -25.78424 1.000 27.43779 ? 102 VAL C N   1 
ATOM   4918 C  CA  . VAL C 1 104 ? 5.70830   -5.05137  -26.97807 1.000 25.22909 ? 102 VAL C CA  1 
ATOM   4919 C  C   . VAL C 1 104 ? 6.96335   -5.88658  -26.74558 1.000 28.33052 ? 102 VAL C C   1 
ATOM   4920 O  O   . VAL C 1 104 ? 7.07110   -7.01320  -27.23307 1.000 31.32872 ? 102 VAL C O   1 
ATOM   4921 C  CB  . VAL C 1 104 ? 5.83976   -4.14898  -28.21974 1.000 26.78015 ? 102 VAL C CB  1 
ATOM   4922 C  CG1 . VAL C 1 104 ? 7.18985   -3.44246  -28.23788 1.000 26.93209 ? 102 VAL C CG1 1 
ATOM   4923 C  CG2 . VAL C 1 104 ? 5.71670   -5.01093  -29.47839 1.000 30.72017 ? 102 VAL C CG2 1 
ATOM   4924 N  N   . ARG C 1 105 ? 7.91882   -5.35407  -25.98149 1.000 29.77791 ? 103 ARG C N   1 
ATOM   4925 C  CA  . ARG C 1 105 ? 9.15747   -6.05694  -25.69311 1.000 27.49220 ? 103 ARG C CA  1 
ATOM   4926 C  C   . ARG C 1 105 ? 8.93209   -7.26250  -24.79116 1.000 33.67672 ? 103 ARG C C   1 
ATOM   4927 O  O   . ARG C 1 105 ? 9.75940   -8.18248  -24.79203 1.000 33.28741 ? 103 ARG C O   1 
ATOM   4928 C  CB  . ARG C 1 105 ? 10.15768  -5.08762  -25.05424 1.000 31.11595 ? 103 ARG C CB  1 
ATOM   4929 C  CG  . ARG C 1 105 ? 10.63672  -3.99271  -25.99270 1.000 29.72816 ? 103 ARG C CG  1 
ATOM   4930 C  CD  . ARG C 1 105 ? 11.91808  -3.32647  -25.45420 1.000 34.94288 ? 103 ARG C CD  1 
ATOM   4931 N  NE  . ARG C 1 105 ? 13.00032  -4.31174  -25.41743 1.000 36.92636 ? 103 ARG C NE  1 
ATOM   4932 C  CZ  . ARG C 1 105 ? 14.21579  -4.07787  -24.93967 1.000 36.62498 ? 103 ARG C CZ  1 
ATOM   4933 N  NH1 . ARG C 1 105 ? 14.56076  -2.88606  -24.48662 1.000 32.73048 ? 103 ARG C NH1 1 
ATOM   4934 N  NH2 . ARG C 1 105 ? 15.11444  -5.06068  -24.93693 1.000 34.37097 ? 103 ARG C NH2 1 
ATOM   4935 N  N   . LEU C 1 106 ? 7.82646   -7.26862  -24.03071 1.000 32.08659 ? 104 LEU C N   1 
ATOM   4936 C  CA  . LEU C 1 106 ? 7.39841   -8.45957  -23.30487 1.000 29.92765 ? 104 LEU C CA  1 
ATOM   4937 C  C   . LEU C 1 106 ? 7.09933   -9.59981  -24.25614 1.000 33.15859 ? 104 LEU C C   1 
ATOM   4938 O  O   . LEU C 1 106 ? 7.37073   -10.77455 -23.94779 1.000 28.49107 ? 104 LEU C O   1 
ATOM   4939 C  CB  . LEU C 1 106 ? 6.14963   -8.14721  -22.48928 1.000 33.13810 ? 104 LEU C CB  1 
ATOM   4940 C  CG  . LEU C 1 106 ? 6.30196   -7.54453  -21.10725 1.000 31.44417 ? 104 LEU C CG  1 
ATOM   4941 C  CD1 . LEU C 1 106 ? 4.90552   -7.32846  -20.53601 1.000 28.26811 ? 104 LEU C CD1 1 
ATOM   4942 C  CD2 . LEU C 1 106 ? 7.09493   -8.47349  -20.21250 1.000 31.23842 ? 104 LEU C CD2 1 
ATOM   4943 N  N   . LEU C 1 107 ? 6.52004   -9.28374  -25.42030 1.000 32.49089 ? 105 LEU C N   1 
ATOM   4944 C  CA  . LEU C 1 107 ? 6.32711   -10.33260 -26.42695 1.000 31.34446 ? 105 LEU C CA  1 
ATOM   4945 C  C   . LEU C 1 107 ? 7.66376   -10.78381 -26.99706 1.000 32.93347 ? 105 LEU C C   1 
ATOM   4946 O  O   . LEU C 1 107 ? 7.91385   -11.98764 -27.17735 1.000 33.59389 ? 105 LEU C O   1 
ATOM   4947 C  CB  . LEU C 1 107 ? 5.40830   -9.82483  -27.53925 1.000 30.91836 ? 105 LEU C CB  1 
ATOM   4948 C  CG  . LEU C 1 107 ? 3.95704   -9.53362  -27.12765 1.000 31.47556 ? 105 LEU C CG  1 
ATOM   4949 C  CD1 . LEU C 1 107 ? 3.08756   -9.28556  -28.33159 1.000 34.35123 ? 105 LEU C CD1 1 
ATOM   4950 C  CD2 . LEU C 1 107 ? 3.38380   -10.66828 -26.34336 1.000 31.25308 ? 105 LEU C CD2 1 
ATOM   4951 N  N   . THR C 1 108 ? 8.54400   -9.83404  -27.30587 1.000 32.04612 ? 106 THR C N   1 
ATOM   4952 C  CA  . THR C 1 108 ? 9.83128   -10.22557 -27.86857 1.000 33.61262 ? 106 THR C CA  1 
ATOM   4953 C  C   . THR C 1 108 ? 10.58187  -11.13959 -26.91173 1.000 34.19939 ? 106 THR C C   1 
ATOM   4954 O  O   . THR C 1 108 ? 11.13615  -12.16371 -27.31984 1.000 31.57450 ? 106 THR C O   1 
ATOM   4955 C  CB  . THR C 1 108 ? 10.68344  -9.00808  -28.16803 1.000 33.57444 ? 106 THR C CB  1 
ATOM   4956 O  OG1 . THR C 1 108 ? 9.95700   -8.09798  -29.01119 1.000 36.45491 ? 106 THR C OG1 1 
ATOM   4957 C  CG2 . THR C 1 108 ? 11.94482  -9.46203  -28.85310 1.000 26.83348 ? 106 THR C CG2 1 
ATOM   4958 N  N   . ASP C 1 109 ? 10.59425  -10.79083 -25.63353 1.000 29.44245 ? 107 ASP C N   1 
ATOM   4959 C  CA  . ASP C 1 109 ? 11.37943  -11.55319 -24.68033 1.000 35.05241 ? 107 ASP C CA  1 
ATOM   4960 C  C   . ASP C 1 109 ? 10.71458  -12.84338 -24.21916 1.000 29.56716 ? 107 ASP C C   1 
ATOM   4961 O  O   . ASP C 1 109 ? 11.43344  -13.74876 -23.77886 1.000 32.29794 ? 107 ASP C O   1 
ATOM   4962 C  CB  . ASP C 1 109 ? 11.70284  -10.67595 -23.45602 1.000 35.15485 ? 107 ASP C CB  1 
ATOM   4963 C  CG  . ASP C 1 109 ? 12.55408  -9.47907  -23.80418 1.000 38.06687 ? 107 ASP C CG  1 
ATOM   4964 O  OD1 . ASP C 1 109 ? 13.25286  -9.50761  -24.85130 1.000 38.11348 ? 107 ASP C OD1 1 
ATOM   4965 O  OD2 . ASP C 1 109 ? 12.54180  -8.50604  -23.01860 1.000 38.80415 ? 107 ASP C OD2 1 
ATOM   4966 N  N   . HIS C 1 110 ? 9.37915   -12.96903 -24.30202 1.000 29.55269 ? 108 HIS C N   1 
ATOM   4967 C  CA  . HIS C 1 110 ? 8.70199   -14.12806 -23.70384 1.000 32.90049 ? 108 HIS C CA  1 
ATOM   4968 C  C   . HIS C 1 110 ? 7.64909   -14.81801 -24.56145 1.000 32.08509 ? 108 HIS C C   1 
ATOM   4969 O  O   . HIS C 1 110 ? 7.26402   -15.94303 -24.21902 1.000 30.47979 ? 108 HIS C O   1 
ATOM   4970 C  CB  . HIS C 1 110 ? 8.04169   -13.74553 -22.37349 1.000 29.30084 ? 108 HIS C CB  1 
ATOM   4971 C  CG  . HIS C 1 110 ? 8.95883   -13.01943 -21.44140 1.000 34.08190 ? 108 HIS C CG  1 
ATOM   4972 N  ND1 . HIS C 1 110 ? 9.98729   -13.64722 -20.76803 1.000 34.41692 ? 108 HIS C ND1 1 
ATOM   4973 C  CD2 . HIS C 1 110 ? 9.00059   -11.72203 -21.06669 1.000 29.60132 ? 108 HIS C CD2 1 
ATOM   4974 C  CE1 . HIS C 1 110 ? 10.63086  -12.76241 -20.02794 1.000 33.53051 ? 108 HIS C CE1 1 
ATOM   4975 N  NE2 . HIS C 1 110 ? 10.05676  -11.58370 -20.20047 1.000 34.06711 ? 108 HIS C NE2 1 
ATOM   4976 N  N   . LEU C 1 111 ? 7.14346   -14.22729 -25.62700 1.000 30.24326 ? 109 LEU C N   1 
ATOM   4977 C  CA  . LEU C 1 111 ? 6.16617   -14.94322 -26.44284 1.000 29.31249 ? 109 LEU C CA  1 
ATOM   4978 C  C   . LEU C 1 111 ? 6.88425   -15.98682 -27.28946 1.000 27.33553 ? 109 LEU C C   1 
ATOM   4979 O  O   . LEU C 1 111 ? 7.71653   -15.61644 -28.12254 1.000 26.88788 ? 109 LEU C O   1 
ATOM   4980 C  CB  . LEU C 1 111 ? 5.40422   -13.98894 -27.35403 1.000 29.96782 ? 109 LEU C CB  1 
ATOM   4981 C  CG  . LEU C 1 111 ? 4.33263   -14.66832 -28.22671 1.000 28.73289 ? 109 LEU C CG  1 
ATOM   4982 C  CD1 . LEU C 1 111 ? 3.21199   -15.26447 -27.38182 1.000 29.50789 ? 109 LEU C CD1 1 
ATOM   4983 C  CD2 . LEU C 1 111 ? 3.77416   -13.63653 -29.23152 1.000 31.60687 ? 109 LEU C CD2 1 
ATOM   4984 N  N   . PRO C 1 112 ? 6.57982   -17.28033 -27.14039 1.000 29.33443 ? 110 PRO C N   1 
ATOM   4985 C  CA  . PRO C 1 112 ? 7.23733   -18.28644 -27.99829 1.000 28.72639 ? 110 PRO C CA  1 
ATOM   4986 C  C   . PRO C 1 112 ? 6.76735   -18.13473 -29.43652 1.000 29.74734 ? 110 PRO C C   1 
ATOM   4987 O  O   . PRO C 1 112 ? 5.56200   -18.16909 -29.71501 1.000 26.96575 ? 110 PRO C O   1 
ATOM   4988 C  CB  . PRO C 1 112 ? 6.79443   -19.62821 -27.40223 1.000 29.54390 ? 110 PRO C CB  1 
ATOM   4989 C  CG  . PRO C 1 112 ? 6.25936   -19.33093 -26.01843 1.000 28.07803 ? 110 PRO C CG  1 
ATOM   4990 C  CD  . PRO C 1 112 ? 5.70019   -17.89251 -26.12857 1.000 29.03885 ? 110 PRO C CD  1 
ATOM   4991 N  N   . GLN C 1 113 ? 7.72341   -17.97805 -30.35621 1.000 27.78569 ? 111 GLN C N   1 
ATOM   4992 C  CA  . GLN C 1 113 ? 7.35215   -17.94143 -31.76963 1.000 29.23729 ? 111 GLN C CA  1 
ATOM   4993 C  C   . GLN C 1 113 ? 6.47061   -19.12319 -32.14255 1.000 27.25883 ? 111 GLN C C   1 
ATOM   4994 O  O   . GLN C 1 113 ? 5.49266   -18.97248 -32.88446 1.000 27.55339 ? 111 GLN C O   1 
ATOM   4995 C  CB  . GLN C 1 113 ? 8.58321   -17.92056 -32.67938 1.000 28.19666 ? 111 GLN C CB  1 
ATOM   4996 C  CG  . GLN C 1 113 ? 8.18357   -18.06173 -34.16348 1.000 30.63635 ? 111 GLN C CG  1 
ATOM   4997 C  CD  . GLN C 1 113 ? 9.35881   -18.14342 -35.11024 1.000 31.39626 ? 111 GLN C CD  1 
ATOM   4998 O  OE1 . GLN C 1 113 ? 10.41391  -18.67940 -34.75801 1.000 31.04619 ? 111 GLN C OE1 1 
ATOM   4999 N  NE2 . GLN C 1 113 ? 9.18406   -17.61861 -36.33187 1.000 26.09753 ? 111 GLN C NE2 1 
ATOM   5000 N  N   . HIS C 1 114 ? 6.77822   -20.30869 -31.61964 1.000 27.61096 ? 112 HIS C N   1 
ATOM   5001 C  CA  . HIS C 1 114 ? 5.99693   -21.46884 -32.02471 1.000 28.41294 ? 112 HIS C CA  1 
ATOM   5002 C  C   . HIS C 1 114 ? 4.54194   -21.35102 -31.57543 1.000 29.19704 ? 112 HIS C C   1 
ATOM   5003 O  O   . HIS C 1 114 ? 3.63243   -21.76079 -32.30587 1.000 28.01810 ? 112 HIS C O   1 
ATOM   5004 C  CB  . HIS C 1 114 ? 6.64654   -22.74952 -31.50226 1.000 27.37348 ? 112 HIS C CB  1 
ATOM   5005 C  CG  . HIS C 1 114 ? 6.06440   -23.98367 -32.09143 1.000 31.72776 ? 112 HIS C CG  1 
ATOM   5006 N  ND1 . HIS C 1 114 ? 4.91203   -24.56071 -31.60434 1.000 29.64720 ? 112 HIS C ND1 1 
ATOM   5007 C  CD2 . HIS C 1 114 ? 6.46994   -24.75455 -33.13249 1.000 32.14753 ? 112 HIS C CD2 1 
ATOM   5008 C  CE1 . HIS C 1 114 ? 4.63913   -25.64547 -32.31275 1.000 34.20028 ? 112 HIS C CE1 1 
ATOM   5009 N  NE2 . HIS C 1 114 ? 5.56771   -25.78283 -33.24663 1.000 32.13757 ? 112 HIS C NE2 1 
ATOM   5010 N  N   . SER C 1 115 ? 4.29474   -20.77487 -30.38660 1.000 28.73543 ? 113 SER C N   1 
ATOM   5011 C  CA  . SER C 1 115 ? 2.91622   -20.54100 -29.95554 1.000 29.26680 ? 113 SER C CA  1 
ATOM   5012 C  C   . SER C 1 115 ? 2.23705   -19.50298 -30.83444 1.000 29.19638 ? 113 SER C C   1 
ATOM   5013 O  O   . SER C 1 115 ? 1.07640   -19.67252 -31.22742 1.000 31.19949 ? 113 SER C O   1 
ATOM   5014 C  CB  . SER C 1 115 ? 2.86629   -20.06537 -28.49846 1.000 29.01191 ? 113 SER C CB  1 
ATOM   5015 O  OG  . SER C 1 115 ? 3.68289   -20.83249 -27.65161 1.000 27.34381 ? 113 SER C OG  1 
ATOM   5016 N  N   . LEU C 1 116 ? 2.93739   -18.40886 -31.13170 1.000 29.96653 ? 114 LEU C N   1 
ATOM   5017 C  CA  . LEU C 1 116 ? 2.39038   -17.40691 -32.03884 1.000 30.40757 ? 114 LEU C CA  1 
ATOM   5018 C  C   . LEU C 1 116 ? 1.94356   -18.04038 -33.36363 1.000 30.90388 ? 114 LEU C C   1 
ATOM   5019 O  O   . LEU C 1 116 ? 0.83160   -17.79005 -33.84182 1.000 33.71051 ? 114 LEU C O   1 
ATOM   5020 C  CB  . LEU C 1 116 ? 3.42405   -16.29780 -32.24684 1.000 28.48942 ? 114 LEU C CB  1 
ATOM   5021 C  CG  . LEU C 1 116 ? 3.07732   -15.11851 -33.14166 1.000 30.38917 ? 114 LEU C CG  1 
ATOM   5022 C  CD1 . LEU C 1 116 ? 3.26512   -15.54534 -34.62996 1.000 28.36354 ? 114 LEU C CD1 1 
ATOM   5023 C  CD2 . LEU C 1 116 ? 1.66554   -14.58888 -32.85948 1.000 28.86435 ? 114 LEU C CD2 1 
ATOM   5024 N  N   . LEU C 1 117 ? 2.80206   -18.84572 -33.98241 1.000 28.99182 ? 115 LEU C N   1 
ATOM   5025 C  CA  . LEU C 1 117 ? 2.45540   -19.41655 -35.29254 1.000 33.79574 ? 115 LEU C CA  1 
ATOM   5026 C  C   . LEU C 1 117 ? 1.21792   -20.31908 -35.20955 1.000 33.32031 ? 115 LEU C C   1 
ATOM   5027 O  O   . LEU C 1 117 ? 0.29345   -20.20468 -36.03080 1.000 32.72856 ? 115 LEU C O   1 
ATOM   5028 C  CB  . LEU C 1 117 ? 3.64357   -20.19336 -35.87741 1.000 32.33352 ? 115 LEU C CB  1 
ATOM   5029 C  CG  . LEU C 1 117 ? 4.80970   -19.30011 -36.30751 1.000 31.95664 ? 115 LEU C CG  1 
ATOM   5030 C  CD1 . LEU C 1 117 ? 5.95382   -20.14991 -36.78870 1.000 25.18411 ? 115 LEU C CD1 1 
ATOM   5031 C  CD2 . LEU C 1 117 ? 4.38092   -18.28579 -37.38731 1.000 31.94799 ? 115 LEU C CD2 1 
ATOM   5032 N  N   . MET C 1 118 ? 1.18075   -21.20828 -34.21237 1.000 29.48967 ? 116 MET C N   1 
ATOM   5033 C  CA  . MET C 1 118 ? -0.01884  -22.00811 -33.94391 1.000 31.92898 ? 116 MET C CA  1 
ATOM   5034 C  C   . MET C 1 118 ? -1.25541  -21.13833 -33.78718 1.000 33.81331 ? 116 MET C C   1 
ATOM   5035 O  O   . MET C 1 118 ? -2.31110  -21.41233 -34.36980 1.000 33.39927 ? 116 MET C O   1 
ATOM   5036 C  CB  . MET C 1 118 ? 0.21682   -22.86118 -32.68850 1.000 30.90230 ? 116 MET C CB  1 
ATOM   5037 C  CG  . MET C 1 118 ? 1.17020   -24.08779 -32.82507 1.000 33.94672 ? 116 MET C CG  1 
ATOM   5038 S  SD  . MET C 1 118 ? 1.19304   -24.99388 -34.40650 1.000 34.25320 ? 116 MET C SD  1 
ATOM   5039 C  CE  . MET C 1 118 ? 2.79091   -24.57392 -35.05450 1.000 34.81513 ? 116 MET C CE  1 
ATOM   5040 N  N   . MET C 1 119 ? -1.13659  -20.07054 -33.00463 1.000 31.47208 ? 117 MET C N   1 
ATOM   5041 C  CA  . MET C 1 119 ? -2.27052  -19.19733 -32.77221 1.000 35.25176 ? 117 MET C CA  1 
ATOM   5042 C  C   . MET C 1 119 ? -2.64531  -18.47560 -34.06225 1.000 33.30420 ? 117 MET C C   1 
ATOM   5043 O  O   . MET C 1 119 ? -3.82433  -18.38519 -34.43364 1.000 35.91455 ? 117 MET C O   1 
ATOM   5044 C  CB  . MET C 1 119 ? -1.86528  -18.22023 -31.66621 1.000 34.19171 ? 117 MET C CB  1 
ATOM   5045 C  CG  . MET C 1 119 ? -2.02759  -18.82808 -30.26915 1.000 29.16162 ? 117 MET C CG  1 
ATOM   5046 S  SD  . MET C 1 119 ? -2.08054  -17.58644 -28.96229 1.000 35.56847 ? 117 MET C SD  1 
ATOM   5047 C  CE  . MET C 1 119 ? -0.38974  -17.01935 -28.91696 1.000 34.72851 ? 117 MET C CE  1 
ATOM   5048 N  N   . ARG C 1 120 ? -1.63740  -17.96462 -34.76217 1.000 30.81705 ? 118 ARG C N   1 
ATOM   5049 C  CA  . ARG C 1 120 ? -1.84518  -17.19165 -35.97538 1.000 33.20312 ? 118 ARG C CA  1 
ATOM   5050 C  C   . ARG C 1 120 ? -2.48579  -18.00824 -37.08596 1.000 36.45684 ? 118 ARG C C   1 
ATOM   5051 O  O   . ARG C 1 120 ? -3.24447  -17.45986 -37.89782 1.000 37.21474 ? 118 ARG C O   1 
ATOM   5052 C  CB  . ARG C 1 120 ? -0.49716  -16.62176 -36.40868 1.000 34.09368 ? 118 ARG C CB  1 
ATOM   5053 C  CG  . ARG C 1 120 ? -0.43017  -15.96971 -37.75276 1.000 41.35270 ? 118 ARG C CG  1 
ATOM   5054 C  CD  . ARG C 1 120 ? 0.95066   -15.33270 -37.92734 1.000 36.20427 ? 118 ARG C CD  1 
ATOM   5055 N  NE  . ARG C 1 120 ? 0.92048   -14.20604 -38.84813 1.000 33.91165 ? 118 ARG C NE  1 
ATOM   5056 C  CZ  . ARG C 1 120 ? 1.01827   -14.34565 -40.16444 1.000 35.57986 ? 118 ARG C CZ  1 
ATOM   5057 N  NH1 . ARG C 1 120 ? 1.14505   -15.54461 -40.72501 1.000 32.13858 ? 118 ARG C NH1 1 
ATOM   5058 N  NH2 . ARG C 1 120 ? 0.96951   -13.26365 -40.93838 1.000 35.23963 ? 118 ARG C NH2 1 
ATOM   5059 N  N   . ASN C 1 121 ? -2.18219  -19.31032 -37.15511 1.000 34.71715 ? 119 ASN C N   1 
ATOM   5060 C  CA  . ASN C 1 121 ? -2.78931  -20.16343 -38.16880 1.000 38.49629 ? 119 ASN C CA  1 
ATOM   5061 C  C   . ASN C 1 121 ? -4.31349  -20.22718 -38.02882 1.000 38.97408 ? 119 ASN C C   1 
ATOM   5062 O  O   . ASN C 1 121 ? -4.99830  -20.55236 -39.00457 1.000 40.43844 ? 119 ASN C O   1 
ATOM   5063 C  CB  . ASN C 1 121 ? -2.16749  -21.57736 -38.10119 1.000 35.46589 ? 119 ASN C CB  1 
ATOM   5064 C  CG  . ASN C 1 121 ? -0.75368  -21.63584 -38.73637 1.000 38.98901 ? 119 ASN C CG  1 
ATOM   5065 O  OD1 . ASN C 1 121 ? -0.35347  -20.74946 -39.51161 1.000 33.44707 ? 119 ASN C OD1 1 
ATOM   5066 N  ND2 . ASN C 1 121 ? 0.00591   -22.66620 -38.38457 1.000 33.58294 ? 119 ASN C ND2 1 
ATOM   5067 N  N   . ALA C 1 122 ? -4.86044  -19.92385 -36.84816 1.000 37.22202 ? 120 ALA C N   1 
ATOM   5068 C  CA  . ALA C 1 122 ? -6.30277  -19.97849 -36.61853 1.000 38.49731 ? 120 ALA C CA  1 
ATOM   5069 C  C   . ALA C 1 122 ? -6.95829  -18.60539 -36.53748 1.000 41.09053 ? 120 ALA C C   1 
ATOM   5070 O  O   . ALA C 1 122 ? -8.18410  -18.53315 -36.40635 1.000 38.51534 ? 120 ALA C O   1 
ATOM   5071 C  CB  . ALA C 1 122 ? -6.61585  -20.75349 -35.33015 1.000 36.51697 ? 120 ALA C CB  1 
ATOM   5072 N  N   . LEU C 1 123 ? -6.18456  -17.52133 -36.60322 1.000 37.05647 ? 121 LEU C N   1 
ATOM   5073 C  CA  . LEU C 1 123 ? -6.74399  -16.19068 -36.39052 1.000 38.24242 ? 121 LEU C CA  1 
ATOM   5074 C  C   . LEU C 1 123 ? -7.57838  -15.75542 -37.59081 1.000 40.26930 ? 121 LEU C C   1 
ATOM   5075 O  O   . LEU C 1 123 ? -7.42085  -16.28251 -38.69172 1.000 37.90176 ? 121 LEU C O   1 
ATOM   5076 C  CB  . LEU C 1 123 ? -5.62139  -15.18181 -36.12989 1.000 36.78052 ? 121 LEU C CB  1 
ATOM   5077 C  CG  . LEU C 1 123 ? -5.08644  -15.22427 -34.69180 1.000 36.00210 ? 121 LEU C CG  1 
ATOM   5078 C  CD1 . LEU C 1 123 ? -3.77711  -14.46104 -34.56562 1.000 36.49191 ? 121 LEU C CD1 1 
ATOM   5079 C  CD2 . LEU C 1 123 ? -6.13764  -14.67799 -33.73972 1.000 41.06452 ? 121 LEU C CD2 1 
ATOM   5080 N  N   . PRO C 1 124 ? -8.47665  -14.78803 -37.41266 1.000 41.95689 ? 122 PRO C N   1 
ATOM   5081 C  CA  . PRO C 1 124 ? -9.21025  -14.26870 -38.57060 1.000 40.29283 ? 122 PRO C CA  1 
ATOM   5082 C  C   . PRO C 1 124 ? -8.27422  -13.65484 -39.59554 1.000 39.47216 ? 122 PRO C C   1 
ATOM   5083 O  O   . PRO C 1 124 ? -7.14879  -13.24038 -39.29777 1.000 40.84115 ? 122 PRO C O   1 
ATOM   5084 C  CB  . PRO C 1 124 ? -10.14862 -13.21871 -37.97334 1.000 36.74578 ? 122 PRO C CB  1 
ATOM   5085 C  CG  . PRO C 1 124 ? -10.24297 -13.54285 -36.53809 1.000 41.26424 ? 122 PRO C CG  1 
ATOM   5086 C  CD  . PRO C 1 124 ? -8.98791  -14.26005 -36.13908 1.000 38.64556 ? 122 PRO C CD  1 
ATOM   5087 N  N   . GLU C 1 125 ? -8.75693  -13.61147 -40.83090 1.000 43.52526 ? 123 GLU C N   1 
ATOM   5088 C  CA  . GLU C 1 125 ? -8.02532  -12.94154 -41.89514 1.000 45.20341 ? 123 GLU C CA  1 
ATOM   5089 C  C   . GLU C 1 125 ? -8.04198  -11.42177 -41.71121 1.000 45.62940 ? 123 GLU C C   1 
ATOM   5090 O  O   . GLU C 1 125 ? -9.00151  -10.83870 -41.19092 1.000 44.14041 ? 123 GLU C O   1 
ATOM   5091 C  CB  . GLU C 1 125 ? -8.59153  -13.36617 -43.25346 1.000 47.93480 ? 123 GLU C CB  1 
ATOM   5092 C  CG  . GLU C 1 125 ? -8.00359  -12.65497 -44.46817 1.000 52.47135 ? 123 GLU C CG  1 
ATOM   5093 C  CD  . GLU C 1 125 ? -8.92939  -12.70339 -45.68523 1.000 55.94363 ? 123 GLU C CD  1 
ATOM   5094 O  OE1 . GLU C 1 125 ? -8.41219  -12.66919 -46.81922 1.000 58.22367 ? 123 GLU C OE1 1 
ATOM   5095 O  OE2 . GLU C 1 125 ? -10.15793 -12.86425 -45.52170 1.000 61.62568 ? 123 GLU C OE2 1 
ATOM   5096 N  N   . ASP C 1 126 ? -6.93283  -10.79039 -42.10476 1.000 44.88421 ? 124 ASP C N   1 
ATOM   5097 C  CA  . ASP C 1 126 ? -6.75452  -9.33541  -42.00532 1.000 43.04813 ? 124 ASP C CA  1 
ATOM   5098 C  C   . ASP C 1 126 ? -7.06053  -8.81450  -40.60018 1.000 43.06135 ? 124 ASP C C   1 
ATOM   5099 O  O   . ASP C 1 126 ? -7.68536  -7.76050  -40.41715 1.000 43.30545 ? 124 ASP C O   1 
ATOM   5100 C  CB  . ASP C 1 126 ? -7.59477  -8.60175  -43.04694 1.000 46.63105 ? 124 ASP C CB  1 
ATOM   5101 C  CG  . ASP C 1 126 ? -7.16144  -7.15063  -43.22795 1.000 49.47600 ? 124 ASP C CG  1 
ATOM   5102 O  OD1 . ASP C 1 126 ? -5.97829  -6.83101  -42.95203 1.000 47.30565 ? 124 ASP C OD1 1 
ATOM   5103 O  OD2 . ASP C 1 126 ? -8.01103  -6.32939  -43.63715 1.000 50.20607 ? 124 ASP C OD2 1 
ATOM   5104 N  N   . ALA C 1 127 ? -6.61002  -9.55648  -39.59628 1.000 37.95300 ? 125 ALA C N   1 
ATOM   5105 C  CA  . ALA C 1 127 ? -6.59861  -9.06952  -38.22137 1.000 36.32088 ? 125 ALA C CA  1 
ATOM   5106 C  C   . ALA C 1 127 ? -5.23445  -8.42629  -38.02268 1.000 38.64426 ? 125 ALA C C   1 
ATOM   5107 O  O   . ALA C 1 127 ? -4.22354  -9.12451  -37.87159 1.000 35.73864 ? 125 ALA C O   1 
ATOM   5108 C  CB  . ALA C 1 127 ? -6.85949  -10.20283 -37.23378 1.000 38.56901 ? 125 ALA C CB  1 
ATOM   5109 N  N   . THR C 1 128 ? -5.21374  -7.08521  -38.02467 1.000 35.14903 ? 126 THR C N   1 
ATOM   5110 C  CA  . THR C 1 128 ? -3.99517  -6.30223  -38.09385 1.000 36.68271 ? 126 THR C CA  1 
ATOM   5111 C  C   . THR C 1 128 ? -4.10411  -5.09823  -37.18161 1.000 34.32524 ? 126 THR C C   1 
ATOM   5112 O  O   . THR C 1 128 ? -5.16679  -4.48787  -37.06640 1.000 34.75202 ? 126 THR C O   1 
ATOM   5113 C  CB  . THR C 1 128 ? -3.70291  -5.77594  -39.52956 1.000 38.94188 ? 126 THR C CB  1 
ATOM   5114 O  OG1 . THR C 1 128 ? -2.63976  -4.84586  -39.45866 1.000 39.47974 ? 126 THR C OG1 1 
ATOM   5115 C  CG2 . THR C 1 128 ? -4.92439  -4.99423  -40.17468 1.000 34.55099 ? 126 THR C CG2 1 
ATOM   5116 N  N   . GLY C 1 129 ? -2.96863  -4.70149  -36.61366 1.000 32.16785 ? 127 GLY C N   1 
ATOM   5117 C  CA  . GLY C 1 129 ? -2.89414  -3.44224  -35.86958 1.000 32.35227 ? 127 GLY C CA  1 
ATOM   5118 C  C   . GLY C 1 129 ? -2.99012  -2.19065  -36.72837 1.000 33.62681 ? 127 GLY C C   1 
ATOM   5119 O  O   . GLY C 1 129 ? -2.99693  -1.08613  -36.18214 1.000 30.63467 ? 127 GLY C O   1 
ATOM   5120 N  N   . LEU C 1 130 ? -3.05655  -2.32454  -38.05161 1.000 34.53277 ? 128 LEU C N   1 
ATOM   5121 C  CA  . LEU C 1 130 ? -3.47040  -1.17288  -38.83719 1.000 33.75572 ? 128 LEU C CA  1 
ATOM   5122 C  C   . LEU C 1 130 ? -4.85778  -0.68209  -38.42773 1.000 37.78839 ? 128 LEU C C   1 
ATOM   5123 O  O   . LEU C 1 130 ? -5.18320  0.49319   -38.64959 1.000 38.95823 ? 128 LEU C O   1 
ATOM   5124 C  CB  . LEU C 1 130 ? -3.42993  -1.49525  -40.32945 1.000 38.93712 ? 128 LEU C CB  1 
ATOM   5125 C  CG  . LEU C 1 130 ? -2.01725  -1.64602  -40.90777 1.000 39.54920 ? 128 LEU C CG  1 
ATOM   5126 C  CD1 . LEU C 1 130 ? -2.03244  -2.35164  -42.25570 1.000 43.41418 ? 128 LEU C CD1 1 
ATOM   5127 C  CD2 . LEU C 1 130 ? -1.30770  -0.30421  -40.99797 1.000 39.26740 ? 128 LEU C CD2 1 
ATOM   5128 N  N   . ASP C 1 131 ? -5.65922  -1.53764  -37.79694 1.000 34.02657 ? 129 ASP C N   1 
ATOM   5129 C  CA  . ASP C 1 131 ? -6.95715  -1.17283  -37.23948 1.000 36.64437 ? 129 ASP C CA  1 
ATOM   5130 C  C   . ASP C 1 131 ? -6.90382  -0.89942  -35.74814 1.000 33.72933 ? 129 ASP C C   1 
ATOM   5131 O  O   . ASP C 1 131 ? -7.95345  -0.81270  -35.11133 1.000 36.71607 ? 129 ASP C O   1 
ATOM   5132 C  CB  . ASP C 1 131 ? -7.98024  -2.27416  -37.51094 1.000 33.81221 ? 129 ASP C CB  1 
ATOM   5133 C  CG  . ASP C 1 131 ? -8.19287  -2.49481  -38.98188 1.000 35.95448 ? 129 ASP C CG  1 
ATOM   5134 O  OD1 . ASP C 1 131 ? -8.36070  -1.47854  -39.68687 1.000 43.46311 ? 129 ASP C OD1 1 
ATOM   5135 O  OD2 . ASP C 1 131 ? -8.15327  -3.65872  -39.42679 1.000 39.60323 ? 129 ASP C OD2 1 
ATOM   5136 N  N   . SER C 1 132 ? -5.72138  -0.76366  -35.17355 1.000 32.98527 ? 130 SER C N   1 
ATOM   5137 C  CA  . SER C 1 132 ? -5.64015  -0.30830  -33.78939 1.000 32.01948 ? 130 SER C CA  1 
ATOM   5138 C  C   . SER C 1 132 ? -6.23427  1.09229   -33.64851 1.000 33.73662 ? 130 SER C C   1 
ATOM   5139 O  O   . SER C 1 132 ? -5.80067  2.02171   -34.34897 1.000 33.32450 ? 130 SER C O   1 
ATOM   5140 C  CB  . SER C 1 132 ? -4.19278  -0.29090  -33.31824 1.000 31.99215 ? 130 SER C CB  1 
ATOM   5141 O  OG  . SER C 1 132 ? -4.08620  0.43480   -32.11658 1.000 31.41843 ? 130 SER C OG  1 
ATOM   5142 N  N   . PRO C 1 133 ? -7.18695  1.30151   -32.73786 1.000 34.73447 ? 131 PRO C N   1 
ATOM   5143 C  CA  . PRO C 1 133 ? -7.67147  2.67241   -32.51991 1.000 34.56268 ? 131 PRO C CA  1 
ATOM   5144 C  C   . PRO C 1 133 ? -6.63342  3.55937   -31.85406 1.000 34.89657 ? 131 PRO C C   1 
ATOM   5145 O  O   . PRO C 1 133 ? -6.52930  4.74694   -32.19892 1.000 32.97423 ? 131 PRO C O   1 
ATOM   5146 C  CB  . PRO C 1 133 ? -8.92250  2.48686   -31.64591 1.000 34.10149 ? 131 PRO C CB  1 
ATOM   5147 C  CG  . PRO C 1 133 ? -8.89410  1.14404   -31.15809 1.000 34.03362 ? 131 PRO C CG  1 
ATOM   5148 C  CD  . PRO C 1 133 ? -7.93114  0.30095   -31.95515 1.000 33.55844 ? 131 PRO C CD  1 
ATOM   5149 N  N   . GLY C 1 134 ? -5.83875  3.02046   -30.92161 1.000 31.22116 ? 132 GLY C N   1 
ATOM   5150 C  CA  . GLY C 1 134 ? -4.74843  3.81418   -30.36523 1.000 31.04770 ? 132 GLY C CA  1 
ATOM   5151 C  C   . GLY C 1 134 ? -3.82055  4.33603   -31.44150 1.000 32.64277 ? 132 GLY C C   1 
ATOM   5152 O  O   . GLY C 1 134 ? -3.37064  5.48770   -31.40095 1.000 29.43193 ? 132 GLY C O   1 
ATOM   5153 N  N   . TYR C 1 135 ? -3.53624  3.50039   -32.43159 1.000 32.70693 ? 133 TYR C N   1 
ATOM   5154 C  CA  . TYR C 1 135 ? -2.60533  3.86329   -33.48690 1.000 32.96238 ? 133 TYR C CA  1 
ATOM   5155 C  C   . TYR C 1 135 ? -3.24384  4.77993   -34.51673 1.000 31.41050 ? 133 TYR C C   1 
ATOM   5156 O  O   . TYR C 1 135 ? -2.62241  5.74491   -34.95966 1.000 35.30456 ? 133 TYR C O   1 
ATOM   5157 C  CB  . TYR C 1 135 ? -2.08527  2.60376   -34.18253 1.000 32.82377 ? 133 TYR C CB  1 
ATOM   5158 C  CG  . TYR C 1 135 ? -0.86298  2.91314   -34.98426 1.000 38.57337 ? 133 TYR C CG  1 
ATOM   5159 C  CD1 . TYR C 1 135 ? 0.32041   3.26392   -34.35899 1.000 41.50982 ? 133 TYR C CD1 1 
ATOM   5160 C  CD2 . TYR C 1 135 ? -0.93085  2.98477   -36.37232 1.000 37.50213 ? 133 TYR C CD2 1 
ATOM   5161 C  CE1 . TYR C 1 135 ? 1.43055   3.59549   -35.09040 1.000 45.79446 ? 133 TYR C CE1 1 
ATOM   5162 C  CE2 . TYR C 1 135 ? 0.18161   3.31575   -37.12458 1.000 44.45119 ? 133 TYR C CE2 1 
ATOM   5163 C  CZ  . TYR C 1 135 ? 1.36245   3.61568   -36.47500 1.000 48.25475 ? 133 TYR C CZ  1 
ATOM   5164 O  OH  . TYR C 1 135 ? 2.49248   3.93852   -37.20110 1.000 54.30512 ? 133 TYR C OH  1 
ATOM   5165 N  N   . ARG C 1 136 ? -4.46752  4.46919   -34.93856 1.000 34.18732 ? 134 ARG C N   1 
ATOM   5166 C  CA  . ARG C 1 136 ? -5.14181  5.29920   -35.92698 1.000 32.27376 ? 134 ARG C CA  1 
ATOM   5167 C  C   . ARG C 1 136 ? -5.44479  6.67810   -35.36570 1.000 32.93566 ? 134 ARG C C   1 
ATOM   5168 O  O   . ARG C 1 136 ? -5.30544  7.68345   -36.07280 1.000 34.61505 ? 134 ARG C O   1 
ATOM   5169 C  CB  . ARG C 1 136 ? -6.42681  4.62339   -36.39854 1.000 37.67249 ? 134 ARG C CB  1 
ATOM   5170 C  CG  . ARG C 1 136 ? -6.21131  3.35503   -37.22852 1.000 35.97093 ? 134 ARG C CG  1 
ATOM   5171 C  CD  . ARG C 1 136 ? -7.53767  2.67790   -37.50298 1.000 41.70940 ? 134 ARG C CD  1 
ATOM   5172 N  NE  . ARG C 1 136 ? -8.39441  3.57677   -38.26621 1.000 51.89369 ? 134 ARG C NE  1 
ATOM   5173 C  CZ  . ARG C 1 136 ? -8.46634  3.57971   -39.58816 1.000 55.76673 ? 134 ARG C CZ  1 
ATOM   5174 N  NH1 . ARG C 1 136 ? -7.81303  2.68952   -40.31505 1.000 57.76679 ? 134 ARG C NH1 1 
ATOM   5175 N  NH2 . ARG C 1 136 ? -9.19736  4.50810   -40.19712 1.000 62.05655 ? 134 ARG C NH2 1 
ATOM   5176 N  N   . ASN C 1 137 ? -5.84074  6.75517   -34.09201 1.000 32.48117 ? 135 ASN C N   1 
ATOM   5177 C  CA  . ASN C 1 137 ? -6.14373  8.06131   -33.51639 1.000 31.55715 ? 135 ASN C CA  1 
ATOM   5178 C  C   . ASN C 1 137 ? -4.89038  8.85589   -33.17871 1.000 30.66326 ? 135 ASN C C   1 
ATOM   5179 O  O   . ASN C 1 137 ? -4.92722  10.08258  -33.20553 1.000 32.16990 ? 135 ASN C O   1 
ATOM   5180 C  CB  . ASN C 1 137 ? -7.02393  7.89022   -32.27263 1.000 30.02206 ? 135 ASN C CB  1 
ATOM   5181 C  CG  . ASN C 1 137 ? -8.38438  7.30833   -32.62078 1.000 37.64990 ? 135 ASN C CG  1 
ATOM   5182 O  OD1 . ASN C 1 137 ? -9.04420  7.79821   -33.54402 1.000 40.55291 ? 135 ASN C OD1 1 
ATOM   5183 N  ND2 . ASN C 1 137 ? -8.80718  6.25396   -31.90580 1.000 30.71103 ? 135 ASN C ND2 1 
ATOM   5184 N  N   . LEU C 1 138 ? -3.79175  8.19923   -32.81086 1.000 30.03201 ? 136 LEU C N   1 
ATOM   5185 C  CA  . LEU C 1 138 ? -2.55742  8.94260   -32.55660 1.000 30.81500 ? 136 LEU C CA  1 
ATOM   5186 C  C   . LEU C 1 138 ? -2.00097  9.54490   -33.84839 1.000 32.42115 ? 136 LEU C C   1 
ATOM   5187 O  O   . LEU C 1 138 ? -1.50166  10.67994  -33.85620 1.000 33.01349 ? 136 LEU C O   1 
ATOM   5188 C  CB  . LEU C 1 138 ? -1.54205  8.01294   -31.87797 1.000 28.79667 ? 136 LEU C CB  1 
ATOM   5189 C  CG  . LEU C 1 138 ? -0.11022  8.50074   -31.69837 1.000 34.36038 ? 136 LEU C CG  1 
ATOM   5190 C  CD1 . LEU C 1 138 ? -0.09056  9.61265   -30.62358 1.000 35.40018 ? 136 LEU C CD1 1 
ATOM   5191 C  CD2 . LEU C 1 138 ? 0.79325   7.34484   -31.28749 1.000 35.28577 ? 136 LEU C CD2 1 
ATOM   5192 N  N   . ARG C 1 139 ? -2.08724  8.80300   -34.95039 1.000 30.97862 ? 137 ARG C N   1 
ATOM   5193 C  CA  . ARG C 1 139 ? -1.68323  9.33275   -36.25437 1.000 33.20533 ? 137 ARG C CA  1 
ATOM   5194 C  C   . ARG C 1 139 ? -2.56783  10.51150  -36.65292 1.000 35.60668 ? 137 ARG C C   1 
ATOM   5195 O  O   . ARG C 1 139 ? -2.08591  11.55103  -37.12410 1.000 35.59722 ? 137 ARG C O   1 
ATOM   5196 C  CB  . ARG C 1 139 ? -1.78207  8.20831   -37.28624 1.000 32.76335 ? 137 ARG C CB  1 
ATOM   5197 C  CG  . ARG C 1 139 ? -1.27176  8.52731   -38.65787 1.000 48.97007 ? 137 ARG C CG  1 
ATOM   5198 C  CD  . ARG C 1 139 ? -1.89399  7.56683   -39.63575 1.000 51.94437 ? 137 ARG C CD  1 
ATOM   5199 N  NE  . ARG C 1 139 ? -0.97670  7.15683   -40.68188 1.000 55.89749 ? 137 ARG C NE  1 
ATOM   5200 C  CZ  . ARG C 1 139 ? -1.08664  7.54666   -41.94328 1.000 64.21383 ? 137 ARG C CZ  1 
ATOM   5201 N  NH1 . ARG C 1 139 ? -1.98156  8.45497   -42.30823 1.000 61.58122 ? 137 ARG C NH1 1 
ATOM   5202 N  NH2 . ARG C 1 139 ? -0.27378  7.02365   -42.85830 1.000 62.89720 ? 137 ARG C NH2 1 
ATOM   5203 N  N   . ARG C 1 140 ? -3.86922  10.37667  -36.41981 1.000 36.89639 ? 138 ARG C N   1 
ATOM   5204 C  CA  . ARG C 1 140 ? -4.81400  11.41729  -36.79654 1.000 36.84584 ? 138 ARG C CA  1 
ATOM   5205 C  C   . ARG C 1 140 ? -4.58066  12.69680  -35.98408 1.000 36.12126 ? 138 ARG C C   1 
ATOM   5206 O  O   . ARG C 1 140 ? -4.57910  13.79831  -36.53843 1.000 34.99912 ? 138 ARG C O   1 
ATOM   5207 C  CB  . ARG C 1 140 ? -6.22428  10.85131  -36.61394 1.000 37.56147 ? 138 ARG C CB  1 
ATOM   5208 C  CG  . ARG C 1 140 ? -7.38482  11.79508  -36.60629 1.000 42.96604 ? 138 ARG C CG  1 
ATOM   5209 C  CD  . ARG C 1 140 ? -8.49920  11.19801  -35.73002 1.000 51.06569 ? 138 ARG C CD  1 
ATOM   5210 N  NE  . ARG C 1 140 ? -9.32581  10.15597  -36.33144 1.000 50.37421 ? 138 ARG C NE  1 
ATOM   5211 C  CZ  . ARG C 1 140 ? -10.05914 10.30873  -37.42349 1.000 53.60937 ? 138 ARG C CZ  1 
ATOM   5212 N  NH1 . ARG C 1 140 ? -10.08048 11.44937  -38.08575 1.000 57.11712 ? 138 ARG C NH1 1 
ATOM   5213 N  NH2 . ARG C 1 140 ? -10.78747 9.28672   -37.86180 1.000 63.47446 ? 138 ARG C NH2 1 
ATOM   5214 N  N   . VAL C 1 141 ? -4.34929  12.56784  -34.67427 1.000 33.84740 ? 139 VAL C N   1 
ATOM   5215 C  CA  . VAL C 1 141 ? -4.23317  13.72671  -33.79745 1.000 31.35763 ? 139 VAL C CA  1 
ATOM   5216 C  C   . VAL C 1 141 ? -2.87598  14.40234  -33.90075 1.000 33.14707 ? 139 VAL C C   1 
ATOM   5217 O  O   . VAL C 1 141 ? -2.73246  15.55557  -33.47647 1.000 33.63915 ? 139 VAL C O   1 
ATOM   5218 C  CB  . VAL C 1 141 ? -4.50094  13.33811  -32.32454 1.000 32.86942 ? 139 VAL C CB  1 
ATOM   5219 C  CG1 . VAL C 1 141 ? -3.23354  12.82085  -31.63863 1.000 31.23733 ? 139 VAL C CG1 1 
ATOM   5220 C  CG2 . VAL C 1 141 ? -5.04782  14.53555  -31.52393 1.000 33.83973 ? 139 VAL C CG2 1 
ATOM   5221 N  N   . ALA C 1 142 ? -1.87645  13.71965  -34.45219 1.000 33.74169 ? 140 ALA C N   1 
ATOM   5222 C  CA  . ALA C 1 142 ? -0.53218  14.27290  -34.48936 1.000 32.56390 ? 140 ALA C CA  1 
ATOM   5223 C  C   . ALA C 1 142 ? -0.46991  15.53461  -35.33549 1.000 33.61909 ? 140 ALA C C   1 
ATOM   5224 O  O   . ALA C 1 142 ? 0.32662   16.42486  -35.04809 1.000 32.62492 ? 140 ALA C O   1 
ATOM   5225 C  CB  . ALA C 1 142 ? 0.44206   13.22722  -35.03307 1.000 32.97868 ? 140 ALA C CB  1 
ATOM   5226 N  N   . ARG C 1 143 ? -1.29383  15.61655  -36.38072 1.000 33.83347 ? 141 ARG C N   1 
ATOM   5227 C  CA  . ARG C 1 143 ? -1.29784  16.81068  -37.22286 1.000 38.93352 ? 141 ARG C CA  1 
ATOM   5228 C  C   . ARG C 1 143 ? -1.83750  18.01811  -36.46738 1.000 37.01570 ? 141 ARG C C   1 
ATOM   5229 O  O   . ARG C 1 143 ? -1.14780  19.05252  -36.42642 1.000 36.69065 ? 141 ARG C O   1 
ATOM   5230 C  CB  . ARG C 1 143 ? -2.07116  16.52843  -38.51566 1.000 40.14197 ? 141 ARG C CB  1 
ATOM   5231 C  CG  . ARG C 1 143 ? -1.28364  15.75666  -39.54931 1.000 46.03704 ? 141 ARG C CG  1 
ATOM   5232 C  CD  . ARG C 1 143 ? -0.13821  16.58984  -40.06473 1.000 51.19041 ? 141 ARG C CD  1 
ATOM   5233 N  NE  . ARG C 1 143 ? 1.13031   16.36393  -39.37719 1.000 49.34253 ? 141 ARG C NE  1 
ATOM   5234 C  CZ  . ARG C 1 143 ? 2.08726   17.28239  -39.31444 1.000 47.26534 ? 141 ARG C CZ  1 
ATOM   5235 N  NH1 . ARG C 1 143 ? 1.92754   18.47731  -39.85856 1.000 49.48656 ? 141 ARG C NH1 1 
ATOM   5236 N  NH2 . ARG C 1 143 ? 3.21775   17.00702  -38.66886 1.000 42.90994 ? 141 ARG C NH2 1 
ATOM   5237 N  N   . PRO C 1 144 ? -3.01786  17.97042  -35.84534 1.000 35.94139 ? 142 PRO C N   1 
ATOM   5238 C  CA  . PRO C 1 144 ? -3.43746  19.12377  -35.03063 1.000 34.86877 ? 142 PRO C CA  1 
ATOM   5239 C  C   . PRO C 1 144 ? -2.45400  19.46036  -33.91742 1.000 33.54122 ? 142 PRO C C   1 
ATOM   5240 O  O   . PRO C 1 144 ? -2.31931  20.63752  -33.56121 1.000 33.45075 ? 142 PRO C O   1 
ATOM   5241 C  CB  . PRO C 1 144 ? -4.79398  18.68533  -34.46055 1.000 36.66428 ? 142 PRO C CB  1 
ATOM   5242 C  CG  . PRO C 1 144 ? -5.28346  17.59227  -35.37258 1.000 38.69678 ? 142 PRO C CG  1 
ATOM   5243 C  CD  . PRO C 1 144 ? -4.07449  16.93765  -35.96678 1.000 33.71351 ? 142 PRO C CD  1 
ATOM   5244 N  N   . VAL C 1 145 ? -1.75842  18.46631  -33.35242 1.000 32.57459 ? 143 VAL C N   1 
ATOM   5245 C  CA  . VAL C 1 145 ? -0.80675  18.75348  -32.27864 1.000 32.13049 ? 143 VAL C CA  1 
ATOM   5246 C  C   . VAL C 1 145 ? 0.34379   19.59555  -32.80875 1.000 31.61283 ? 143 VAL C C   1 
ATOM   5247 O  O   . VAL C 1 145 ? 0.74877   20.59970  -32.20167 1.000 29.25546 ? 143 VAL C O   1 
ATOM   5248 C  CB  . VAL C 1 145 ? -0.28617  17.45090  -31.65119 1.000 33.06777 ? 143 VAL C CB  1 
ATOM   5249 C  CG1 . VAL C 1 145 ? 0.91634   17.74216  -30.76610 1.000 27.90813 ? 143 VAL C CG1 1 
ATOM   5250 C  CG2 . VAL C 1 145 ? -1.40874  16.73313  -30.89476 1.000 31.64261 ? 143 VAL C CG2 1 
ATOM   5251 N  N   . TRP C 1 146 ? 0.89131   19.19133  -33.95066 1.000 32.75539 ? 144 TRP C N   1 
ATOM   5252 C  CA  . TRP C 1 146 ? 1.99650   19.93688  -34.53466 1.000 33.55072 ? 144 TRP C CA  1 
ATOM   5253 C  C   . TRP C 1 146 ? 1.55629   21.33615  -34.94591 1.000 32.42411 ? 144 TRP C C   1 
ATOM   5254 O  O   . TRP C 1 146 ? 2.28792   22.31336  -34.75042 1.000 30.56064 ? 144 TRP C O   1 
ATOM   5255 C  CB  . TRP C 1 146 ? 2.56392   19.21071  -35.75790 1.000 32.74858 ? 144 TRP C CB  1 
ATOM   5256 C  CG  . TRP C 1 146 ? 3.53090   20.16762  -36.37260 1.000 35.43055 ? 144 TRP C CG  1 
ATOM   5257 C  CD1 . TRP C 1 146 ? 3.35584   20.93265  -37.49104 1.000 35.38396 ? 144 TRP C CD1 1 
ATOM   5258 C  CD2 . TRP C 1 146 ? 4.79728   20.52010  -35.82933 1.000 33.57539 ? 144 TRP C CD2 1 
ATOM   5259 N  NE1 . TRP C 1 146 ? 4.45738   21.73480  -37.68364 1.000 35.45740 ? 144 TRP C NE1 1 
ATOM   5260 C  CE2 . TRP C 1 146 ? 5.35516   21.50273  -36.66968 1.000 37.40567 ? 144 TRP C CE2 1 
ATOM   5261 C  CE3 . TRP C 1 146 ? 5.51698   20.09417  -34.70159 1.000 34.43058 ? 144 TRP C CE3 1 
ATOM   5262 C  CZ2 . TRP C 1 146 ? 6.60849   22.07034  -36.42419 1.000 36.28506 ? 144 TRP C CZ2 1 
ATOM   5263 C  CZ3 . TRP C 1 146 ? 6.75812   20.65618  -34.45486 1.000 35.72157 ? 144 TRP C CZ3 1 
ATOM   5264 C  CH2 . TRP C 1 146 ? 7.29701   21.62946  -35.32000 1.000 33.55713 ? 144 TRP C CH2 1 
ATOM   5265 N  N   . LYS C 1 147 ? 0.37009   21.44751  -35.53565 1.000 31.32929 ? 145 LYS C N   1 
ATOM   5266 C  CA  . LYS C 1 147 ? -0.11413  22.75827  -35.94343 1.000 34.52044 ? 145 LYS C CA  1 
ATOM   5267 C  C   . LYS C 1 147 ? -0.23074  23.68777  -34.74039 1.000 36.62340 ? 145 LYS C C   1 
ATOM   5268 O  O   . LYS C 1 147 ? 0.18122   24.85082  -34.80221 1.000 34.45884 ? 145 LYS C O   1 
ATOM   5269 C  CB  . LYS C 1 147 ? -1.44333  22.60292  -36.68357 1.000 36.59533 ? 145 LYS C CB  1 
ATOM   5270 C  CG  . LYS C 1 147 ? -1.23480  22.12367  -38.12937 1.000 45.16729 ? 145 LYS C CG  1 
ATOM   5271 C  CD  . LYS C 1 147 ? -2.51583  22.06940  -38.97762 1.000 50.53116 ? 145 LYS C CD  1 
ATOM   5272 C  CE  . LYS C 1 147 ? -2.39391  21.01519  -40.09287 1.000 52.33699 ? 145 LYS C CE  1 
ATOM   5273 N  NZ  . LYS C 1 147 ? -3.71283  20.70032  -40.71413 1.000 59.33788 ? 145 LYS C NZ  1 
ATOM   5274 N  N   . ALA C 1 148 ? -0.69826  23.16340  -33.60270 1.000 33.83185 ? 146 ALA C N   1 
ATOM   5275 C  CA  . ALA C 1 148 ? -0.80818  23.99835  -32.40907 1.000 29.67213 ? 146 ALA C CA  1 
ATOM   5276 C  C   . ALA C 1 148 ? 0.55345   24.50625  -31.95212 1.000 32.24992 ? 146 ALA C C   1 
ATOM   5277 O  O   . ALA C 1 148 ? 0.68343   25.67150  -31.55177 1.000 33.27002 ? 146 ALA C O   1 
ATOM   5278 C  CB  . ALA C 1 148 ? -1.49207  23.22035  -31.28960 1.000 33.38606 ? 146 ALA C CB  1 
ATOM   5279 N  N   . TYR C 1 149 ? 1.58420   23.65832  -31.99250 1.000 27.60079 ? 147 TYR C N   1 
ATOM   5280 C  CA  . TYR C 1 149 ? 2.91948   24.11434  -31.60735 1.000 27.83760 ? 147 TYR C CA  1 
ATOM   5281 C  C   . TYR C 1 149 ? 3.44329   25.15994  -32.59237 1.000 31.69227 ? 147 TYR C C   1 
ATOM   5282 O  O   . TYR C 1 149 ? 3.96287   26.21485  -32.19735 1.000 32.32180 ? 147 TYR C O   1 
ATOM   5283 C  CB  . TYR C 1 149 ? 3.88813   22.92922  -31.52835 1.000 27.08988 ? 147 TYR C CB  1 
ATOM   5284 C  CG  . TYR C 1 149 ? 5.25874   23.38615  -31.07503 1.000 28.90854 ? 147 TYR C CG  1 
ATOM   5285 C  CD1 . TYR C 1 149 ? 5.44416   23.89824  -29.79862 1.000 27.58989 ? 147 TYR C CD1 1 
ATOM   5286 C  CD2 . TYR C 1 149 ? 6.35587   23.32524  -31.92086 1.000 28.69441 ? 147 TYR C CD2 1 
ATOM   5287 C  CE1 . TYR C 1 149 ? 6.68541   24.35580  -29.36697 1.000 28.23923 ? 147 TYR C CE1 1 
ATOM   5288 C  CE2 . TYR C 1 149 ? 7.61377   23.79765  -31.50116 1.000 33.38261 ? 147 TYR C CE2 1 
ATOM   5289 C  CZ  . TYR C 1 149 ? 7.76303   24.31145  -30.21906 1.000 31.73148 ? 147 TYR C CZ  1 
ATOM   5290 O  OH  . TYR C 1 149 ? 8.98767   24.78327  -29.78229 1.000 31.54828 ? 147 TYR C OH  1 
ATOM   5291 N  N   . GLU C 1 150 ? 3.33051   24.85675  -33.88384 1.000 31.66461 ? 148 GLU C N   1 
ATOM   5292 C  CA  . GLU C 1 150 ? 3.79370   25.74861  -34.93768 1.000 33.55016 ? 148 GLU C CA  1 
ATOM   5293 C  C   . GLU C 1 150 ? 3.15554   27.12772  -34.82078 1.000 35.08104 ? 148 GLU C C   1 
ATOM   5294 O  O   . GLU C 1 150 ? 3.84826   28.14910  -34.90250 1.000 36.20953 ? 148 GLU C O   1 
ATOM   5295 C  CB  . GLU C 1 150 ? 3.48844   25.09460  -36.28144 1.000 32.11713 ? 148 GLU C CB  1 
ATOM   5296 C  CG  . GLU C 1 150 ? 3.68395   25.93829  -37.51332 1.000 41.36579 ? 148 GLU C CG  1 
ATOM   5297 C  CD  . GLU C 1 150 ? 3.20284   25.19143  -38.72984 1.000 43.93853 ? 148 GLU C CD  1 
ATOM   5298 O  OE1 . GLU C 1 150 ? 1.96998   25.10352  -38.92582 1.000 49.07727 ? 148 GLU C OE1 1 
ATOM   5299 O  OE2 . GLU C 1 150 ? 4.05228   24.63351  -39.45412 1.000 47.95402 ? 148 GLU C OE2 1 
ATOM   5300 N  N   . GLN C 1 151 ? 1.83230   27.17756  -34.62910 1.000 35.20513 ? 149 GLN C N   1 
ATOM   5301 C  CA  . GLN C 1 151 ? 1.16035   28.46115  -34.48148 1.000 37.14071 ? 149 GLN C CA  1 
ATOM   5302 C  C   . GLN C 1 151 ? 1.63838   29.17076  -33.22256 1.000 36.91288 ? 149 GLN C C   1 
ATOM   5303 O  O   . GLN C 1 151 ? 1.74997   30.39157  -33.21207 1.000 35.44900 ? 149 GLN C O   1 
ATOM   5304 C  CB  . GLN C 1 151 ? -0.35422  28.30143  -34.39525 1.000 38.55942 ? 149 GLN C CB  1 
ATOM   5305 C  CG  . GLN C 1 151 ? -1.02674  27.48014  -35.44637 1.000 44.53663 ? 149 GLN C CG  1 
ATOM   5306 C  CD  . GLN C 1 151 ? -1.41198  28.21368  -36.66586 1.000 56.71080 ? 149 GLN C CD  1 
ATOM   5307 O  OE1 . GLN C 1 151 ? -0.66009  29.05527  -37.18937 1.000 60.27109 ? 149 GLN C OE1 1 
ATOM   5308 N  NE2 . GLN C 1 151 ? -2.63164  27.93018  -37.13653 1.000 61.01369 ? 149 GLN C NE2 1 
ATOM   5309 N  N   . ALA C 1 152 ? 1.89734   28.42822  -32.13243 1.000 34.92089 ? 150 ALA C N   1 
ATOM   5310 C  CA  . ALA C 1 152 ? 2.37388   29.10902  -30.92785 1.000 36.11089 ? 150 ALA C CA  1 
ATOM   5311 C  C   . ALA C 1 152 ? 3.75888   29.70676  -31.16160 1.000 36.00982 ? 150 ALA C C   1 
ATOM   5312 O  O   . ALA C 1 152 ? 4.05357   30.81786  -30.70007 1.000 34.54000 ? 150 ALA C O   1 
ATOM   5313 C  CB  . ALA C 1 152 ? 2.39116   28.16480  -29.72377 1.000 30.01560 ? 150 ALA C CB  1 
ATOM   5314 N  N   . VAL C 1 153 ? 4.60752   29.00305  -31.90221 1.000 33.34720 ? 151 VAL C N   1 
ATOM   5315 C  CA  . VAL C 1 153 ? 5.93240   29.53720  -32.20831 1.000 34.28098 ? 151 VAL C CA  1 
ATOM   5316 C  C   . VAL C 1 153 ? 5.82116   30.80472  -33.05917 1.000 34.99432 ? 151 VAL C C   1 
ATOM   5317 O  O   . VAL C 1 153 ? 6.46218   31.82292  -32.77035 1.000 33.18039 ? 151 VAL C O   1 
ATOM   5318 C  CB  . VAL C 1 153 ? 6.79056   28.46642  -32.89018 1.000 32.75575 ? 151 VAL C CB  1 
ATOM   5319 C  CG1 . VAL C 1 153 ? 8.10248   29.07864  -33.33597 1.000 32.43619 ? 151 VAL C CG1 1 
ATOM   5320 C  CG2 . VAL C 1 153 ? 7.00767   27.28476  -31.90532 1.000 32.16072 ? 151 VAL C CG2 1 
ATOM   5321 N  N   . GLU C 1 154 ? 4.99728   30.75877  -34.11000 1.000 34.38315 ? 152 GLU C N   1 
ATOM   5322 C  CA  . GLU C 1 154 ? 4.78414   31.93204  -34.95893 1.000 35.79219 ? 152 GLU C CA  1 
ATOM   5323 C  C   . GLU C 1 154 ? 4.29091   33.12367  -34.14684 1.000 40.01378 ? 152 GLU C C   1 
ATOM   5324 O  O   . GLU C 1 154 ? 4.77020   34.25043  -34.32811 1.000 35.48278 ? 152 GLU C O   1 
ATOM   5325 C  CB  . GLU C 1 154 ? 3.75251   31.61770  -36.02884 1.000 41.27340 ? 152 GLU C CB  1 
ATOM   5326 C  CG  . GLU C 1 154 ? 4.24761   30.89359  -37.24339 1.000 46.60776 ? 152 GLU C CG  1 
ATOM   5327 C  CD  . GLU C 1 154 ? 3.08467   30.24856  -37.97011 1.000 49.85586 ? 152 GLU C CD  1 
ATOM   5328 O  OE1 . GLU C 1 154 ? 1.91916   30.62989  -37.70673 1.000 51.94313 ? 152 GLU C OE1 1 
ATOM   5329 O  OE2 . GLU C 1 154 ? 3.32503   29.33056  -38.76887 1.000 53.75466 ? 152 GLU C OE2 1 
ATOM   5330 N  N   . ARG C 1 155 ? 3.27723   32.90116  -33.28837 1.000 36.60780 ? 153 ARG C N   1 
ATOM   5331 C  CA  . ARG C 1 155 ? 2.71334   34.00106  -32.51250 1.000 34.60107 ? 153 ARG C CA  1 
ATOM   5332 C  C   . ARG C 1 155 ? 3.77279   34.66123  -31.65829 1.000 36.60522 ? 153 ARG C C   1 
ATOM   5333 O  O   . ARG C 1 155 ? 3.74079   35.87448  -31.46313 1.000 33.69910 ? 153 ARG C O   1 
ATOM   5334 C  CB  . ARG C 1 155 ? 1.56887   33.52195  -31.61634 1.000 33.47990 ? 153 ARG C CB  1 
ATOM   5335 C  CG  . ARG C 1 155 ? 0.29925   33.18578  -32.34990 1.000 34.99368 ? 153 ARG C CG  1 
ATOM   5336 C  CD  . ARG C 1 155 ? -0.87299  33.15405  -31.38534 1.000 36.66839 ? 153 ARG C CD  1 
ATOM   5337 N  NE  . ARG C 1 155 ? -0.73077  32.11396  -30.36738 1.000 37.05081 ? 153 ARG C NE  1 
ATOM   5338 C  CZ  . ARG C 1 155 ? -1.03770  30.83231  -30.54276 1.000 37.65564 ? 153 ARG C CZ  1 
ATOM   5339 N  NH1 . ARG C 1 155 ? -1.55710  30.38774  -31.67359 1.000 37.97416 ? 153 ARG C NH1 1 
ATOM   5340 N  NH2 . ARG C 1 155 ? -0.79316  29.97036  -29.56732 1.000 33.08187 ? 153 ARG C NH2 1 
ATOM   5341 N  N   . ALA C 1 156 ? 4.71962   33.89077  -31.14807 1.000 33.58168 ? 154 ALA C N   1 
ATOM   5342 C  CA  . ALA C 1 156 ? 5.80435   34.47524  -30.36923 1.000 35.86386 ? 154 ALA C CA  1 
ATOM   5343 C  C   . ALA C 1 156 ? 6.87921   35.11061  -31.23991 1.000 35.90191 ? 154 ALA C C   1 
ATOM   5344 O  O   . ALA C 1 156 ? 7.86230   35.63128  -30.70000 1.000 37.97915 ? 154 ALA C O   1 
ATOM   5345 C  CB  . ALA C 1 156 ? 6.42844   33.39651  -29.47591 1.000 35.90567 ? 154 ALA C CB  1 
ATOM   5346 N  N   . GLY C 1 157 ? 6.73348   35.06916  -32.55982 1.000 36.50731 ? 155 GLY C N   1 
ATOM   5347 C  CA  . GLY C 1 157 ? 7.73917   35.67133  -33.43180 1.000 41.82979 ? 155 GLY C CA  1 
ATOM   5348 C  C   . GLY C 1 157 ? 9.08475   34.97986  -33.36884 1.000 40.42047 ? 155 GLY C C   1 
ATOM   5349 O  O   . GLY C 1 157 ? 10.12630  35.64754  -33.42047 1.000 38.61514 ? 155 GLY C O   1 
ATOM   5350 N  N   . LEU C 1 158 ? 9.08636   33.65664  -33.22484 1.000 33.64220 ? 156 LEU C N   1 
ATOM   5351 C  CA  . LEU C 1 158 ? 10.29521  32.86920  -33.07192 1.000 33.26536 ? 156 LEU C CA  1 
ATOM   5352 C  C   . LEU C 1 158 ? 10.43216  31.94172  -34.26857 1.000 32.22761 ? 156 LEU C C   1 
ATOM   5353 O  O   . LEU C 1 158 ? 9.45641   31.63828  -34.95552 1.000 35.82001 ? 156 LEU C O   1 
ATOM   5354 C  CB  . LEU C 1 158 ? 10.25530  32.02913  -31.77330 1.000 33.67394 ? 156 LEU C CB  1 
ATOM   5355 C  CG  . LEU C 1 158 ? 10.15747  32.82329  -30.47165 1.000 36.81574 ? 156 LEU C CG  1 
ATOM   5356 C  CD1 . LEU C 1 158 ? 9.83816   31.90110  -29.30421 1.000 33.00494 ? 156 LEU C CD1 1 
ATOM   5357 C  CD2 . LEU C 1 158 ? 11.43391  33.64672  -30.22060 1.000 38.38672 ? 156 LEU C CD2 1 
ATOM   5358 N  N   . SER C 1 159 ? 11.65074  31.48479  -34.51111 1.000 34.56281 ? 157 SER C N   1 
ATOM   5359 C  CA  . SER C 1 159 ? 11.89257  30.40358  -35.46149 1.000 33.59884 ? 157 SER C CA  1 
ATOM   5360 C  C   . SER C 1 159 ? 12.20297  29.12044  -34.70414 1.000 30.98780 ? 157 SER C C   1 
ATOM   5361 O  O   . SER C 1 159 ? 12.58460  29.16147  -33.53420 1.000 30.90166 ? 157 SER C O   1 
ATOM   5362 C  CB  . SER C 1 159 ? 13.04983  30.75723  -36.40261 1.000 35.59019 ? 157 SER C CB  1 
ATOM   5363 O  OG  . SER C 1 159 ? 14.29199  30.70754  -35.71797 1.000 33.64075 ? 157 SER C OG  1 
ATOM   5364 N  N   . LEU C 1 160 ? 12.02968  27.96883  -35.37973 1.000 30.75671 ? 158 LEU C N   1 
ATOM   5365 C  CA  . LEU C 1 160 ? 12.43335  26.70152  -34.75779 1.000 32.48796 ? 158 LEU C CA  1 
ATOM   5366 C  C   . LEU C 1 160 ? 13.93609  26.67257  -34.49038 1.000 31.91781 ? 158 LEU C C   1 
ATOM   5367 O  O   . LEU C 1 160 ? 14.38180  26.10348  -33.48605 1.000 30.45628 ? 158 LEU C O   1 
ATOM   5368 C  CB  . LEU C 1 160 ? 12.03494  25.50230  -35.62906 1.000 29.26287 ? 158 LEU C CB  1 
ATOM   5369 C  CG  . LEU C 1 160 ? 10.54537  25.13745  -35.66645 1.000 34.20670 ? 158 LEU C CG  1 
ATOM   5370 C  CD1 . LEU C 1 160 ? 10.27337  24.02235  -36.67167 1.000 35.29736 ? 158 LEU C CD1 1 
ATOM   5371 C  CD2 . LEU C 1 160 ? 10.08468  24.70473  -34.29700 1.000 36.08501 ? 158 LEU C CD2 1 
ATOM   5372 N  N   . GLN C 1 161 ? 14.73316  27.28997  -35.36363 1.000 28.19670 ? 159 GLN C N   1 
ATOM   5373 C  CA  . GLN C 1 161 ? 16.17477  27.35614  -35.10152 1.000 31.35412 ? 159 GLN C CA  1 
ATOM   5374 C  C   . GLN C 1 161 ? 16.46284  28.04345  -33.77372 1.000 30.63070 ? 159 GLN C C   1 
ATOM   5375 O  O   . GLN C 1 161 ? 17.33989  27.60105  -33.01555 1.000 29.36630 ? 159 GLN C O   1 
ATOM   5376 C  CB  . GLN C 1 161 ? 16.90056  28.07217  -36.24361 1.000 27.87009 ? 159 GLN C CB  1 
ATOM   5377 C  CG  . GLN C 1 161 ? 17.07214  27.20824  -37.48770 1.000 25.91752 ? 159 GLN C CG  1 
ATOM   5378 C  CD  . GLN C 1 161 ? 17.52385  25.77762  -37.15470 1.000 29.96314 ? 159 GLN C CD  1 
ATOM   5379 O  OE1 . GLN C 1 161 ? 18.55973  25.58378  -36.51743 1.000 31.67059 ? 159 GLN C OE1 1 
ATOM   5380 N  NE2 . GLN C 1 161 ? 16.75203  24.77747  -37.58945 1.000 33.04073 ? 159 GLN C NE2 1 
ATOM   5381 N  N   . ASP C 1 162 ? 15.71185  29.11158  -33.47583 1.000 28.69725 ? 160 ASP C N   1 
ATOM   5382 C  CA  A ASP C 1 162 ? 15.81870  29.83153  -32.20403 0.484 32.79747 ? 160 ASP C CA  1 
ATOM   5383 C  CA  B ASP C 1 162 ? 15.91252  29.81968  -32.21720 0.516 32.79001 ? 160 ASP C CA  1 
ATOM   5384 C  C   . ASP C 1 162 ? 15.59333  28.92158  -31.02518 1.000 30.38977 ? 160 ASP C C   1 
ATOM   5385 O  O   . ASP C 1 162 ? 16.37212  28.88814  -30.06452 1.000 33.85778 ? 160 ASP C O   1 
ATOM   5386 C  CB  A ASP C 1 162 ? 14.74690  30.90938  -32.11759 0.484 34.44626 ? 160 ASP C CB  1 
ATOM   5387 C  CB  B ASP C 1 162 ? 15.08182  31.12012  -32.20147 0.516 34.08750 ? 160 ASP C CB  1 
ATOM   5388 C  CG  A ASP C 1 162 ? 15.06215  32.06319  -32.91412 0.484 32.41488 ? 160 ASP C CG  1 
ATOM   5389 C  CG  B ASP C 1 162 ? 15.61187  32.19085  -31.22047 0.516 34.59708 ? 160 ASP C CG  1 
ATOM   5390 O  OD1 A ASP C 1 162 ? 16.26644  32.24002  -33.14497 0.484 35.28003 ? 160 ASP C OD1 1 
ATOM   5391 O  OD1 B ASP C 1 162 ? 16.78681  32.15731  -30.77557 0.516 33.41795 ? 160 ASP C OD1 1 
ATOM   5392 O  OD2 A ASP C 1 162 ? 14.11067  32.78794  -33.27270 0.484 33.39907 ? 160 ASP C OD2 1 
ATOM   5393 O  OD2 B ASP C 1 162 ? 14.82472  33.12810  -30.92557 0.516 36.17091 ? 160 ASP C OD2 1 
ATOM   5394 N  N   . VAL C 1 163 ? 14.45921  28.21255  -31.04913 1.000 30.87072 ? 161 VAL C N   1 
ATOM   5395 C  CA  . VAL C 1 163 ? 14.13906  27.43772  -29.86335 1.000 28.60281 ? 161 VAL C CA  1 
ATOM   5396 C  C   . VAL C 1 163 ? 15.09232  26.25690  -29.73092 1.000 30.00663 ? 161 VAL C C   1 
ATOM   5397 O  O   . VAL C 1 163 ? 15.44927  25.87526  -28.61219 1.000 32.34288 ? 161 VAL C O   1 
ATOM   5398 C  CB  . VAL C 1 163 ? 12.63995  27.03333  -29.82816 1.000 35.40360 ? 161 VAL C CB  1 
ATOM   5399 C  CG1 . VAL C 1 163 ? 11.73815  28.24121  -30.18300 1.000 36.78302 ? 161 VAL C CG1 1 
ATOM   5400 C  CG2 . VAL C 1 163 ? 12.32413  25.85711  -30.70213 1.000 36.09126 ? 161 VAL C CG2 1 
ATOM   5401 N  N   . ILE C 1 164 ? 15.55797  25.68028  -30.85070 1.000 28.29757 ? 162 ILE C N   1 
ATOM   5402 C  CA  . ILE C 1 164 ? 16.59014  24.63828  -30.76954 1.000 27.22501 ? 162 ILE C CA  1 
ATOM   5403 C  C   . ILE C 1 164 ? 17.87177  25.20207  -30.16210 1.000 27.86116 ? 162 ILE C C   1 
ATOM   5404 O  O   . ILE C 1 164 ? 18.49552  24.58044  -29.29524 1.000 29.74222 ? 162 ILE C O   1 
ATOM   5405 C  CB  . ILE C 1 164 ? 16.87723  24.04499  -32.16588 1.000 31.00867 ? 162 ILE C CB  1 
ATOM   5406 C  CG1 . ILE C 1 164 ? 15.76067  23.12367  -32.64676 1.000 29.67624 ? 162 ILE C CG1 1 
ATOM   5407 C  CG2 . ILE C 1 164 ? 18.20602  23.29627  -32.18391 1.000 29.55009 ? 162 ILE C CG2 1 
ATOM   5408 C  CD1 . ILE C 1 164 ? 15.80500  22.89905  -34.15475 1.000 29.42226 ? 162 ILE C CD1 1 
ATOM   5409 N  N   . ALA C 1 165 ? 18.31273  26.36552  -30.65502 1.000 28.42804 ? 163 ALA C N   1 
ATOM   5410 C  CA  . ALA C 1 165 ? 19.57127  26.94682  -30.19376 1.000 28.79937 ? 163 ALA C CA  1 
ATOM   5411 C  C   . ALA C 1 165 ? 19.53138  27.25915  -28.70222 1.000 29.15735 ? 163 ALA C C   1 
ATOM   5412 O  O   . ALA C 1 165 ? 20.54005  27.10455  -28.00535 1.000 31.13606 ? 163 ALA C O   1 
ATOM   5413 C  CB  . ALA C 1 165 ? 19.89115  28.21614  -30.99449 1.000 32.76769 ? 163 ALA C CB  1 
ATOM   5414 N  N   . GLN C 1 166 ? 18.36854  27.66654  -28.18600 1.000 29.33549 ? 164 GLN C N   1 
ATOM   5415 C  CA  . GLN C 1 166 ? 18.26986  28.06845  -26.78601 1.000 27.98158 ? 164 GLN C CA  1 
ATOM   5416 C  C   . GLN C 1 166 ? 18.34250  26.89065  -25.82655 1.000 31.29777 ? 164 GLN C C   1 
ATOM   5417 O  O   . GLN C 1 166 ? 18.42656  27.09706  -24.61402 1.000 35.57354 ? 164 GLN C O   1 
ATOM   5418 C  CB  . GLN C 1 166 ? 16.98772  28.86412  -26.58432 1.000 30.65851 ? 164 GLN C CB  1 
ATOM   5419 C  CG  . GLN C 1 166 ? 17.15026  30.25991  -27.18246 1.000 30.36937 ? 164 GLN C CG  1 
ATOM   5420 C  CD  . GLN C 1 166 ? 15.94086  31.14626  -27.02981 1.000 35.44445 ? 164 GLN C CD  1 
ATOM   5421 O  OE1 . GLN C 1 166 ? 15.26871  31.13789  -25.99567 1.000 32.30863 ? 164 GLN C OE1 1 
ATOM   5422 N  NE2 . GLN C 1 166 ? 15.67369  31.95447  -28.05869 1.000 30.51386 ? 164 GLN C NE2 1 
ATOM   5423 N  N   . GLN C 1 167 ? 18.32233  25.66648  -26.32372 1.000 25.84345 ? 165 GLN C N   1 
ATOM   5424 C  CA  . GLN C 1 167 ? 18.56896  24.53171  -25.42984 1.000 29.97408 ? 165 GLN C CA  1 
ATOM   5425 C  C   . GLN C 1 167 ? 20.03323  24.46872  -24.97422 1.000 32.67223 ? 165 GLN C C   1 
ATOM   5426 O  O   . GLN C 1 167 ? 20.33864  23.86989  -23.93520 1.000 29.70952 ? 165 GLN C O   1 
ATOM   5427 C  CB  . GLN C 1 167 ? 18.17333  23.23927  -26.13810 1.000 29.20167 ? 165 GLN C CB  1 
ATOM   5428 C  CG  . GLN C 1 167 ? 18.15570  22.02509  -25.21018 1.000 29.77228 ? 165 GLN C CG  1 
ATOM   5429 C  CD  . GLN C 1 167 ? 17.94939  20.72691  -25.96562 1.000 30.00157 ? 165 GLN C CD  1 
ATOM   5430 O  OE1 . GLN C 1 167 ? 17.91668  20.70038  -27.21053 1.000 33.17548 ? 165 GLN C OE1 1 
ATOM   5431 N  NE2 . GLN C 1 167 ? 17.88899  19.62736  -25.22188 1.000 28.51523 ? 165 GLN C NE2 1 
ATOM   5432 N  N   . ASP C 1 168 ? 20.93015  25.10119  -25.72594 1.000 32.47779 ? 166 ASP C N   1 
ATOM   5433 C  CA  . ASP C 1 168 ? 22.36813  25.11356  -25.46695 1.000 32.20712 ? 166 ASP C CA  1 
ATOM   5434 C  C   . ASP C 1 168 ? 22.69986  26.27125  -24.52219 1.000 31.91572 ? 166 ASP C C   1 
ATOM   5435 O  O   . ASP C 1 168 ? 22.47973  27.43597  -24.86235 1.000 33.52792 ? 166 ASP C O   1 
ATOM   5436 C  CB  . ASP C 1 168 ? 23.08218  25.24915  -26.81862 1.000 31.71909 ? 166 ASP C CB  1 
ATOM   5437 C  CG  . ASP C 1 168 ? 24.61201  25.29656  -26.72708 1.000 32.98761 ? 166 ASP C CG  1 
ATOM   5438 O  OD1 . ASP C 1 168 ? 25.18816  25.34689  -25.63190 1.000 31.24188 ? 166 ASP C OD1 1 
ATOM   5439 O  OD2 . ASP C 1 168 ? 25.24396  25.35695  -27.81189 1.000 31.44296 ? 166 ASP C OD2 1 
ATOM   5440 N  N   . ASP C 1 169 ? 23.20224  25.95691  -23.32053 1.000 32.86084 ? 167 ASP C N   1 
ATOM   5441 C  CA  . ASP C 1 169 ? 23.59989  27.02388  -22.39514 1.000 33.86655 ? 167 ASP C CA  1 
ATOM   5442 C  C   . ASP C 1 169 ? 24.64867  27.96240  -22.99553 1.000 36.63040 ? 167 ASP C C   1 
ATOM   5443 O  O   . ASP C 1 169 ? 24.76083  29.12016  -22.56561 1.000 35.26745 ? 167 ASP C O   1 
ATOM   5444 C  CB  . ASP C 1 169 ? 24.15603  26.42246  -21.10797 1.000 34.79796 ? 167 ASP C CB  1 
ATOM   5445 C  CG  . ASP C 1 169 ? 23.06454  25.80355  -20.20109 1.000 33.82567 ? 167 ASP C CG  1 
ATOM   5446 O  OD1 . ASP C 1 169 ? 21.85983  25.95653  -20.46814 1.000 34.25058 ? 167 ASP C OD1 1 
ATOM   5447 O  OD2 . ASP C 1 169 ? 23.43184  25.13509  -19.22558 1.000 32.76286 ? 167 ASP C OD2 1 
ATOM   5448 N  N   . GLY C 1 170 ? 25.44404  27.49062  -23.95714 1.000 37.98615 ? 168 GLY C N   1 
ATOM   5449 C  CA  . GLY C 1 170 ? 26.42473  28.38099  -24.56101 1.000 37.12356 ? 168 GLY C CA  1 
ATOM   5450 C  C   . GLY C 1 170 ? 25.89094  29.30706  -25.62934 1.000 36.76872 ? 168 GLY C C   1 
ATOM   5451 O  O   . GLY C 1 170 ? 26.60657  30.22628  -26.05147 1.000 34.67133 ? 168 GLY C O   1 
ATOM   5452 N  N   . TYR C 1 171 ? 24.65705  29.10460  -26.08611 1.000 33.99921 ? 169 TYR C N   1 
ATOM   5453 C  CA  . TYR C 1 171 ? 24.13031  29.95884  -27.15074 1.000 34.06276 ? 169 TYR C CA  1 
ATOM   5454 C  C   . TYR C 1 171 ? 23.76754  31.32803  -26.60037 1.000 33.73738 ? 169 TYR C C   1 
ATOM   5455 O  O   . TYR C 1 171 ? 23.00916  31.42147  -25.62832 1.000 33.06861 ? 169 TYR C O   1 
ATOM   5456 C  CB  . TYR C 1 171 ? 22.90701  29.31194  -27.77983 1.000 35.72633 ? 169 TYR C CB  1 
ATOM   5457 C  CG  . TYR C 1 171 ? 22.15531  30.22173  -28.70414 1.000 32.23607 ? 169 TYR C CG  1 
ATOM   5458 C  CD1 . TYR C 1 171 ? 22.70180  30.61095  -29.93918 1.000 33.45524 ? 169 TYR C CD1 1 
ATOM   5459 C  CD2 . TYR C 1 171 ? 20.89207  30.68478  -28.35850 1.000 32.52156 ? 169 TYR C CD2 1 
ATOM   5460 C  CE1 . TYR C 1 171 ? 21.98525  31.47071  -30.79930 1.000 32.78397 ? 169 TYR C CE1 1 
ATOM   5461 C  CE2 . TYR C 1 171 ? 20.17938  31.54175  -29.19812 1.000 32.48661 ? 169 TYR C CE2 1 
ATOM   5462 C  CZ  . TYR C 1 171 ? 20.72773  31.90451  -30.42027 1.000 31.51088 ? 169 TYR C CZ  1 
ATOM   5463 O  OH  . TYR C 1 171 ? 20.00213  32.72289  -31.24437 1.000 35.25256 ? 169 TYR C OH  1 
ATOM   5464 N  N   . ASP C 1 172 ? 24.28139  32.39370  -27.24544 1.000 33.84775 ? 170 ASP C N   1 
ATOM   5465 C  CA  . ASP C 1 172 ? 24.22407  33.75271  -26.71072 1.000 35.20567 ? 170 ASP C CA  1 
ATOM   5466 C  C   . ASP C 1 172 ? 23.11469  34.62584  -27.30923 1.000 35.43694 ? 170 ASP C C   1 
ATOM   5467 O  O   . ASP C 1 172 ? 23.05686  35.81815  -27.00363 1.000 35.44836 ? 170 ASP C O   1 
ATOM   5468 C  CB  . ASP C 1 172 ? 25.59354  34.46081  -26.85953 1.000 35.55185 ? 170 ASP C CB  1 
ATOM   5469 C  CG  . ASP C 1 172 ? 25.94647  34.86702  -28.32541 1.000 42.83961 ? 170 ASP C CG  1 
ATOM   5470 O  OD1 . ASP C 1 172 ? 25.14655  34.66313  -29.26332 1.000 40.41628 ? 170 ASP C OD1 1 
ATOM   5471 O  OD2 . ASP C 1 172 ? 27.06304  35.41523  -28.54360 1.000 45.17315 ? 170 ASP C OD2 1 
ATOM   5472 N  N   . GLY C 1 173 ? 22.22771  34.07870  -28.12796 1.000 34.80803 ? 171 GLY C N   1 
ATOM   5473 C  CA  . GLY C 1 173 ? 21.12765  34.85543  -28.66155 1.000 31.78025 ? 171 GLY C CA  1 
ATOM   5474 C  C   . GLY C 1 173 ? 20.17994  35.35420  -27.58340 1.000 37.23799 ? 171 GLY C C   1 
ATOM   5475 O  O   . GLY C 1 173 ? 20.13277  34.82188  -26.47115 1.000 36.63365 ? 171 GLY C O   1 
ATOM   5476 N  N   . PRO C 1 174 ? 19.41284  36.39947  -27.88338 1.000 38.99787 ? 172 PRO C N   1 
ATOM   5477 C  CA  . PRO C 1 174 ? 18.47245  36.91623  -26.88516 1.000 37.35991 ? 172 PRO C CA  1 
ATOM   5478 C  C   . PRO C 1 174 ? 17.36785  35.91877  -26.60812 1.000 38.84594 ? 172 PRO C C   1 
ATOM   5479 O  O   . PRO C 1 174 ? 16.91471  35.19795  -27.50374 1.000 37.13246 ? 172 PRO C O   1 
ATOM   5480 C  CB  . PRO C 1 174 ? 17.92687  38.20208  -27.52814 1.000 39.10238 ? 172 PRO C CB  1 
ATOM   5481 C  CG  . PRO C 1 174 ? 18.83861  38.49368  -28.65847 1.000 36.51383 ? 172 PRO C CG  1 
ATOM   5482 C  CD  . PRO C 1 174 ? 19.42017  37.21959  -29.11225 1.000 36.42426 ? 172 PRO C CD  1 
ATOM   5483 N  N   . ARG C 1 175 ? 16.96380  35.86247  -25.33493 1.000 34.54529 ? 173 ARG C N   1 
ATOM   5484 C  CA  . ARG C 1 175 ? 15.97488  34.91946  -24.85635 1.000 34.82219 ? 173 ARG C CA  1 
ATOM   5485 C  C   . ARG C 1 175 ? 14.88241  35.65513  -24.10019 1.000 39.19917 ? 173 ARG C C   1 
ATOM   5486 O  O   . ARG C 1 175 ? 15.08080  36.75872  -23.59248 1.000 37.02651 ? 173 ARG C O   1 
ATOM   5487 C  CB  . ARG C 1 175 ? 16.59672  33.88009  -23.92813 1.000 35.78905 ? 173 ARG C CB  1 
ATOM   5488 C  CG  . ARG C 1 175 ? 17.83356  33.19373  -24.48381 1.000 29.94110 ? 173 ARG C CG  1 
ATOM   5489 C  CD  . ARG C 1 175 ? 18.17286  32.00749  -23.59036 1.000 33.14677 ? 173 ARG C CD  1 
ATOM   5490 N  NE  . ARG C 1 175 ? 19.43161  31.40019  -23.99321 1.000 35.27208 ? 173 ARG C NE  1 
ATOM   5491 C  CZ  . ARG C 1 175 ? 19.87750  30.22890  -23.56329 1.000 32.42297 ? 173 ARG C CZ  1 
ATOM   5492 N  NH1 . ARG C 1 175 ? 19.19633  29.50581  -22.68236 1.000 33.10982 ? 173 ARG C NH1 1 
ATOM   5493 N  NH2 . ARG C 1 175 ? 21.03331  29.77180  -24.03174 1.000 33.41754 ? 173 ARG C NH2 1 
ATOM   5494 N  N   . SER C 1 176 ? 13.72034  35.01958  -24.01329 1.000 32.85943 ? 174 SER C N   1 
ATOM   5495 C  CA  . SER C 1 176 ? 12.64604  35.50245  -23.16860 1.000 35.82269 ? 174 SER C CA  1 
ATOM   5496 C  C   . SER C 1 176 ? 12.11699  34.31672  -22.38086 1.000 35.56193 ? 174 SER C C   1 
ATOM   5497 O  O   . SER C 1 176 ? 12.48932  33.16938  -22.63725 1.000 33.74104 ? 174 SER C O   1 
ATOM   5498 C  CB  . SER C 1 176 ? 11.52646  36.13287  -23.99780 1.000 38.19113 ? 174 SER C CB  1 
ATOM   5499 O  OG  . SER C 1 176 ? 10.97026  35.12100  -24.82904 1.000 33.25437 ? 174 SER C OG  1 
ATOM   5500 N  N   . GLY C 1 177 ? 11.21938  34.59931  -21.43657 1.000 34.72313 ? 175 GLY C N   1 
ATOM   5501 C  CA  . GLY C 1 177 ? 10.52676  33.51707  -20.75799 1.000 34.76675 ? 175 GLY C CA  1 
ATOM   5502 C  C   . GLY C 1 177 ? 9.73109   32.66348  -21.72369 1.000 33.33987 ? 175 GLY C C   1 
ATOM   5503 O  O   . GLY C 1 177 ? 9.75358   31.43771  -21.64678 1.000 32.97395 ? 175 GLY C O   1 
ATOM   5504 N  N   . GLY C 1 178 ? 9.03182   33.30118  -22.65754 1.000 30.93548 ? 176 GLY C N   1 
ATOM   5505 C  CA  . GLY C 1 178 ? 8.29618   32.54543  -23.65216 1.000 31.66875 ? 176 GLY C CA  1 
ATOM   5506 C  C   . GLY C 1 178 ? 9.19076   31.68401  -24.53066 1.000 33.60152 ? 176 GLY C C   1 
ATOM   5507 O  O   . GLY C 1 178 ? 8.87275   30.52873  -24.80403 1.000 28.17725 ? 176 GLY C O   1 
ATOM   5508 N  N   . SER C 1 179 ? 10.31239  32.23194  -25.00959 1.000 32.79939 ? 177 SER C N   1 
ATOM   5509 C  CA  . SER C 1 179 ? 11.09767  31.43957  -25.95892 1.000 34.90318 ? 177 SER C CA  1 
ATOM   5510 C  C   . SER C 1 179 ? 11.67870  30.19781  -25.28660 1.000 30.38076 ? 177 SER C C   1 
ATOM   5511 O  O   . SER C 1 179 ? 11.72330  29.12144  -25.88796 1.000 29.57226 ? 177 SER C O   1 
ATOM   5512 C  CB  . SER C 1 179 ? 12.20589  32.28193  -26.61198 1.000 30.00786 ? 177 SER C CB  1 
ATOM   5513 O  OG  . SER C 1 179 ? 13.21767  32.64505  -25.69591 1.000 31.84689 ? 177 SER C OG  1 
ATOM   5514 N  N   . GLN C 1 180 ? 12.09001  30.31796  -24.02790 1.000 30.42503 ? 178 GLN C N   1 
ATOM   5515 C  CA  . GLN C 1 180 ? 12.68552  29.17573  -23.36057 1.000 29.52420 ? 178 GLN C CA  1 
ATOM   5516 C  C   . GLN C 1 180 ? 11.62044  28.15244  -22.99785 1.000 31.41064 ? 178 GLN C C   1 
ATOM   5517 O  O   . GLN C 1 180 ? 11.86767  26.94299  -23.05802 1.000 29.75255 ? 178 GLN C O   1 
ATOM   5518 C  CB  . GLN C 1 180 ? 13.45766  29.65850  -22.14131 1.000 30.33217 ? 178 GLN C CB  1 
ATOM   5519 C  CG  . GLN C 1 180 ? 14.59555  30.56962  -22.54562 1.000 31.22963 ? 178 GLN C CG  1 
ATOM   5520 C  CD  . GLN C 1 180 ? 15.63605  30.76761  -21.47187 1.000 32.01475 ? 178 GLN C CD  1 
ATOM   5521 O  OE1 . GLN C 1 180 ? 16.51067  29.92758  -21.29741 1.000 31.53849 ? 178 GLN C OE1 1 
ATOM   5522 N  NE2 . GLN C 1 180 ? 15.59686  31.92318  -20.79532 1.000 33.59578 ? 178 GLN C NE2 1 
ATOM   5523 N  N   . SER C 1 181 ? 10.42712  28.62701  -22.62602 1.000 31.34372 ? 179 SER C N   1 
ATOM   5524 C  CA  . SER C 1 181 ? 9.28771   27.74594  -22.42389 1.000 33.48890 ? 179 SER C CA  1 
ATOM   5525 C  C   . SER C 1 181 ? 8.95550   26.97673  -23.69463 1.000 31.52044 ? 179 SER C C   1 
ATOM   5526 O  O   . SER C 1 181 ? 8.65918   25.77918  -23.64100 1.000 28.65679 ? 179 SER C O   1 
ATOM   5527 C  CB  . SER C 1 181 ? 8.07271   28.55649  -21.96499 1.000 31.72281 ? 179 SER C CB  1 
ATOM   5528 O  OG  . SER C 1 181 ? 8.23047   28.95555  -20.60800 1.000 34.76385 ? 179 SER C OG  1 
ATOM   5529 N  N   . LEU C 1 182 ? 8.94911   27.65409  -24.83888 1.000 26.62409 ? 180 LEU C N   1 
ATOM   5530 C  CA  . LEU C 1 182 ? 8.64393   26.96297  -26.09285 1.000 29.12971 ? 180 LEU C CA  1 
ATOM   5531 C  C   . LEU C 1 182 ? 9.74605   25.98757  -26.50258 1.000 29.48952 ? 180 LEU C C   1 
ATOM   5532 O  O   . LEU C 1 182 ? 9.47038   24.99625  -27.19583 1.000 26.67023 ? 180 LEU C O   1 
ATOM   5533 C  CB  . LEU C 1 182 ? 8.40096   27.99708  -27.20247 1.000 28.08871 ? 180 LEU C CB  1 
ATOM   5534 C  CG  . LEU C 1 182 ? 6.97507   28.57028  -27.19841 1.000 30.74690 ? 180 LEU C CG  1 
ATOM   5535 C  CD1 . LEU C 1 182 ? 6.87130   29.84167  -28.04849 1.000 28.40201 ? 180 LEU C CD1 1 
ATOM   5536 C  CD2 . LEU C 1 182 ? 6.00757   27.47354  -27.73143 1.000 29.74630 ? 180 LEU C CD2 1 
ATOM   5537 N  N   . ALA C 1 183 ? 10.99089  26.26301  -26.10613 1.000 26.86941 ? 181 ALA C N   1 
ATOM   5538 C  CA  . ALA C 1 183 ? 12.06620  25.28871  -26.25796 1.000 27.93785 ? 181 ALA C CA  1 
ATOM   5539 C  C   . ALA C 1 183 ? 11.79318  24.03384  -25.44539 1.000 30.30634 ? 181 ALA C C   1 
ATOM   5540 O  O   . ALA C 1 183 ? 11.92443  22.91248  -25.94732 1.000 28.17092 ? 181 ALA C O   1 
ATOM   5541 C  CB  . ALA C 1 183 ? 13.38715  25.91621  -25.81483 1.000 29.17204 ? 181 ALA C CB  1 
ATOM   5542 N  N   . LEU C 1 184 ? 11.46321  24.20082  -24.15547 1.000 28.42148 ? 182 LEU C N   1 
ATOM   5543 C  CA  . LEU C 1 184 ? 11.11975  23.04037  -23.34712 1.000 27.43886 ? 182 LEU C CA  1 
ATOM   5544 C  C   . LEU C 1 184 ? 9.97766   22.25714  -23.98559 1.000 27.47830 ? 182 LEU C C   1 
ATOM   5545 O  O   . LEU C 1 184 ? 9.95082   21.02460  -23.91993 1.000 27.48488 ? 182 LEU C O   1 
ATOM   5546 C  CB  . LEU C 1 184 ? 10.73264  23.47469  -21.91514 1.000 29.13152 ? 182 LEU C CB  1 
ATOM   5547 C  CG  . LEU C 1 184 ? 11.82025  24.03115  -20.98327 1.000 31.02907 ? 182 LEU C CG  1 
ATOM   5548 C  CD1 . LEU C 1 184 ? 11.22646  24.50926  -19.65056 1.000 30.47293 ? 182 LEU C CD1 1 
ATOM   5549 C  CD2 . LEU C 1 184 ? 12.92286  23.00185  -20.72345 1.000 28.55418 ? 182 LEU C CD2 1 
ATOM   5550 N  N   . VAL C 1 185 ? 8.99993   22.94698  -24.58465 1.000 27.27161 ? 183 VAL C N   1 
ATOM   5551 C  CA  . VAL C 1 185 ? 7.91916   22.21405  -25.25216 1.000 28.12861 ? 183 VAL C CA  1 
ATOM   5552 C  C   . VAL C 1 185 ? 8.47675   21.41966  -26.42731 1.000 30.70620 ? 183 VAL C C   1 
ATOM   5553 O  O   . VAL C 1 185 ? 8.14231   20.23755  -26.63286 1.000 28.57530 ? 183 VAL C O   1 
ATOM   5554 C  CB  . VAL C 1 185 ? 6.80251   23.17063  -25.71304 1.000 26.97991 ? 183 VAL C CB  1 
ATOM   5555 C  CG1 . VAL C 1 185 ? 5.83817   22.40620  -26.59449 1.000 27.60623 ? 183 VAL C CG1 1 
ATOM   5556 C  CG2 . VAL C 1 185 ? 6.05319   23.74458  -24.52534 1.000 27.66501 ? 183 VAL C CG2 1 
ATOM   5557 N  N   . ARG C 1 186 ? 9.34779   22.05582  -27.21626 1.000 29.31426 ? 184 ARG C N   1 
ATOM   5558 C  CA  . ARG C 1 186 ? 9.93971   21.33136  -28.33644 1.000 29.24203 ? 184 ARG C CA  1 
ATOM   5559 C  C   . ARG C 1 186 ? 10.69229  20.10830  -27.84475 1.000 30.63305 ? 184 ARG C C   1 
ATOM   5560 O  O   . ARG C 1 186 ? 10.58405  19.02902  -28.42750 1.000 31.66325 ? 184 ARG C O   1 
ATOM   5561 C  CB  . ARG C 1 186 ? 10.88158  22.21966  -29.14007 1.000 28.86860 ? 184 ARG C CB  1 
ATOM   5562 C  CG  . ARG C 1 186 ? 11.50002  21.45009  -30.32014 1.000 33.35664 ? 184 ARG C CG  1 
ATOM   5563 C  CD  . ARG C 1 186 ? 12.81722  22.06010  -30.78471 1.000 33.59483 ? 184 ARG C CD  1 
ATOM   5564 N  NE  . ARG C 1 186 ? 13.91197  21.86441  -29.84108 1.000 32.45387 ? 184 ARG C NE  1 
ATOM   5565 C  CZ  . ARG C 1 186 ? 14.85035  20.93320  -29.92800 1.000 32.65147 ? 184 ARG C CZ  1 
ATOM   5566 N  NH1 . ARG C 1 186 ? 14.80205  19.98164  -30.84523 1.000 30.43115 ? 184 ARG C NH1 1 
ATOM   5567 N  NH2 . ARG C 1 186 ? 15.88240  20.97820  -29.09088 1.000 32.85947 ? 184 ARG C NH2 1 
ATOM   5568 N  N   . GLU C 1 187 ? 11.45786  20.25881  -26.77206 1.000 28.71769 ? 185 GLU C N   1 
ATOM   5569 C  CA  . GLU C 1 187 ? 12.27113  19.14477  -26.32039 1.000 28.92283 ? 185 GLU C CA  1 
ATOM   5570 C  C   . GLU C 1 187 ? 11.37991  18.00030  -25.86786 1.000 30.38127 ? 185 GLU C C   1 
ATOM   5571 O  O   . GLU C 1 187 ? 11.67327  16.82875  -26.12766 1.000 27.31614 ? 185 GLU C O   1 
ATOM   5572 C  CB  . GLU C 1 187 ? 13.20862  19.62953  -25.21736 1.000 28.49229 ? 185 GLU C CB  1 
ATOM   5573 C  CG  . GLU C 1 187 ? 14.24685  20.65590  -25.76644 1.000 27.27370 ? 185 GLU C CG  1 
ATOM   5574 C  CD  . GLU C 1 187 ? 14.67314  21.68355  -24.74595 1.000 29.25188 ? 185 GLU C CD  1 
ATOM   5575 O  OE1 . GLU C 1 187 ? 14.79989  21.32298  -23.55339 1.000 29.85176 ? 185 GLU C OE1 1 
ATOM   5576 O  OE2 . GLU C 1 187 ? 14.91197  22.85042  -25.14614 1.000 27.46261 ? 185 GLU C OE2 1 
ATOM   5577 N  N   . ALA C 1 188 ? 10.24681  18.33089  -25.24972 1.000 29.83490 ? 186 ALA C N   1 
ATOM   5578 C  CA  . ALA C 1 188 ? 9.31795   17.29448  -24.83830 1.000 29.48175 ? 186 ALA C CA  1 
ATOM   5579 C  C   . ALA C 1 188 ? 8.63299   16.65431  -26.03466 1.000 28.49664 ? 186 ALA C C   1 
ATOM   5580 O  O   . ALA C 1 188 ? 8.41125   15.43779  -26.04128 1.000 28.22563 ? 186 ALA C O   1 
ATOM   5581 C  CB  . ALA C 1 188 ? 8.29112   17.86547  -23.87413 1.000 27.62108 ? 186 ALA C CB  1 
ATOM   5582 N  N   . MET C 1 189 ? 8.26467   17.42989  -27.05374 1.000 25.96843 ? 187 MET C N   1 
ATOM   5583 C  CA  . MET C 1 189 ? 7.68455   16.72789  -28.18998 1.000 31.00598 ? 187 MET C CA  1 
ATOM   5584 C  C   . MET C 1 189 ? 8.69750   15.84840  -28.90475 1.000 28.81146 ? 187 MET C C   1 
ATOM   5585 O  O   . MET C 1 189 ? 8.32204   14.79464  -29.42512 1.000 29.71767 ? 187 MET C O   1 
ATOM   5586 C  CB  . MET C 1 189 ? 6.95041   17.64484  -29.20335 1.000 31.91924 ? 187 MET C CB  1 
ATOM   5587 C  CG  . MET C 1 189 ? 6.05062   18.72473  -28.65529 1.000 27.45237 ? 187 MET C CG  1 
ATOM   5588 S  SD  . MET C 1 189 ? 5.73828   20.10626  -29.76604 1.000 31.60164 ? 187 MET C SD  1 
ATOM   5589 C  CE  . MET C 1 189 ? 4.90174   19.19507  -31.07689 1.000 30.57995 ? 187 MET C CE  1 
ATOM   5590 N  N   . LEU C 1 190 ? 9.97052   16.22650  -28.90154 1.000 30.34186 ? 188 LEU C N   1 
ATOM   5591 C  CA  . LEU C 1 190 ? 10.97397  15.38750  -29.54225 1.000 31.30309 ? 188 LEU C CA  1 
ATOM   5592 C  C   . LEU C 1 190 ? 11.16060  14.08738  -28.77721 1.000 31.54890 ? 188 LEU C C   1 
ATOM   5593 O  O   . LEU C 1 190 ? 11.29408  13.01890  -29.38990 1.000 28.44961 ? 188 LEU C O   1 
ATOM   5594 C  CB  . LEU C 1 190 ? 12.30178  16.14731  -29.68569 1.000 31.07710 ? 188 LEU C CB  1 
ATOM   5595 C  CG  . LEU C 1 190 ? 13.39552  15.47916  -30.51804 1.000 35.87809 ? 188 LEU C CG  1 
ATOM   5596 C  CD1 . LEU C 1 190 ? 12.90288  15.13608  -31.91888 1.000 33.93569 ? 188 LEU C CD1 1 
ATOM   5597 C  CD2 . LEU C 1 190 ? 14.63325  16.39562  -30.61396 1.000 35.02472 ? 188 LEU C CD2 1 
ATOM   5598 N  N   . ARG C 1 191 ? 11.14445  14.14620  -27.43941 1.000 30.36153 ? 189 ARG C N   1 
ATOM   5599 C  CA  . ARG C 1 191 ? 11.25108  12.90895  -26.67144 1.000 30.26779 ? 189 ARG C CA  1 
ATOM   5600 C  C   . ARG C 1 191 ? 10.06070  11.99705  -26.93165 1.000 29.70214 ? 189 ARG C C   1 
ATOM   5601 O  O   . ARG C 1 191 ? 10.22549  10.78075  -27.08011 1.000 30.29158 ? 189 ARG C O   1 
ATOM   5602 C  CB  . ARG C 1 191 ? 11.36758  13.21791  -25.18407 1.000 29.49569 ? 189 ARG C CB  1 
ATOM   5603 C  CG  . ARG C 1 191 ? 12.73579  13.74444  -24.79433 1.000 34.76214 ? 189 ARG C CG  1 
ATOM   5604 C  CD  . ARG C 1 191 ? 12.83422  13.85894  -23.27720 1.000 34.00077 ? 189 ARG C CD  1 
ATOM   5605 N  NE  . ARG C 1 191 ? 11.86576  14.79560  -22.71808 1.000 30.62740 ? 189 ARG C NE  1 
ATOM   5606 C  CZ  . ARG C 1 191 ? 12.15811  16.05382  -22.43837 1.000 34.35340 ? 189 ARG C CZ  1 
ATOM   5607 N  NH1 . ARG C 1 191 ? 13.36008  16.54953  -22.68554 1.000 33.80223 ? 189 ARG C NH1 1 
ATOM   5608 N  NH2 . ARG C 1 191 ? 11.23150  16.82767  -21.87786 1.000 34.33378 ? 189 ARG C NH2 1 
ATOM   5609 N  N   . LEU C 1 192 ? 8.84961   12.56955  -26.99252 1.000 27.02908 ? 190 LEU C N   1 
ATOM   5610 C  CA  . LEU C 1 192 ? 7.66528   11.77724  -27.31996 1.000 27.23543 ? 190 LEU C CA  1 
ATOM   5611 C  C   . LEU C 1 192 ? 7.81101   11.09509  -28.68431 1.000 25.34442 ? 190 LEU C C   1 
ATOM   5612 O  O   . LEU C 1 192 ? 7.62102   9.88102   -28.81001 1.000 29.51893 ? 190 LEU C O   1 
ATOM   5613 C  CB  . LEU C 1 192 ? 6.41966   12.66698  -27.31276 1.000 27.78290 ? 190 LEU C CB  1 
ATOM   5614 C  CG  . LEU C 1 192 ? 5.15800   11.96913  -27.85458 1.000 27.22610 ? 190 LEU C CG  1 
ATOM   5615 C  CD1 . LEU C 1 192 ? 4.86692   10.70143  -27.08570 1.000 29.24760 ? 190 LEU C CD1 1 
ATOM   5616 C  CD2 . LEU C 1 192 ? 3.95306   12.94630  -27.84619 1.000 29.97050 ? 190 LEU C CD2 1 
ATOM   5617 N  N   . ASP C 1 193 ? 8.11698   11.86980  -29.72562 1.000 27.21994 ? 191 ASP C N   1 
ATOM   5618 C  CA  . ASP C 1 193 ? 8.23072   11.29329  -31.05904 1.000 29.21760 ? 191 ASP C CA  1 
ATOM   5619 C  C   . ASP C 1 193 ? 9.35222   10.24974  -31.09914 1.000 28.90647 ? 191 ASP C C   1 
ATOM   5620 O  O   . ASP C 1 193 ? 9.19571   9.18653   -31.69983 1.000 26.16805 ? 191 ASP C O   1 
ATOM   5621 C  CB  . ASP C 1 193 ? 8.44682   12.41922  -32.08063 1.000 26.99314 ? 191 ASP C CB  1 
ATOM   5622 C  CG  . ASP C 1 193 ? 7.89028   12.09294  -33.45908 1.000 30.51348 ? 191 ASP C CG  1 
ATOM   5623 O  OD1 . ASP C 1 193 ? 7.24857   11.02735  -33.64453 1.000 31.60621 ? 191 ASP C OD1 1 
ATOM   5624 O  OD2 . ASP C 1 193 ? 8.09260   12.90473  -34.37468 1.000 31.45414 ? 191 ASP C OD2 1 
ATOM   5625 N  N   . GLY C 1 194 ? 10.47735  10.51200  -30.42454 1.000 28.47735 ? 192 GLY C N   1 
ATOM   5626 C  CA  . GLY C 1 194 ? 11.52422  9.49644   -30.36507 1.000 28.53448 ? 192 GLY C CA  1 
ATOM   5627 C  C   . GLY C 1 194 ? 11.06218  8.22500   -29.67528 1.000 32.83968 ? 192 GLY C C   1 
ATOM   5628 O  O   . GLY C 1 194 ? 11.46824  7.12240   -30.04623 1.000 29.12443 ? 192 GLY C O   1 
ATOM   5629 N  N   . SER C 1 195 ? 10.22377  8.36543   -28.63880 1.000 32.53281 ? 193 SER C N   1 
ATOM   5630 C  CA  . SER C 1 195 ? 9.69064   7.19171   -27.97061 1.000 30.28433 ? 193 SER C CA  1 
ATOM   5631 C  C   . SER C 1 195 ? 8.78176   6.40920   -28.90975 1.000 29.18423 ? 193 SER C C   1 
ATOM   5632 O  O   . SER C 1 195 ? 8.84563   5.17854   -28.96454 1.000 28.76272 ? 193 SER C O   1 
ATOM   5633 C  CB  . SER C 1 195 ? 8.94742   7.59947   -26.68157 1.000 27.54954 ? 193 SER C CB  1 
ATOM   5634 O  OG  . SER C 1 195 ? 8.27105   6.46962   -26.13063 1.000 26.85590 ? 193 SER C OG  1 
ATOM   5635 N  N   . VAL C 1 196 ? 7.97323   7.10479   -29.70617 1.000 28.13260 ? 194 VAL C N   1 
ATOM   5636 C  CA  . VAL C 1 196 ? 7.05954   6.39031   -30.59090 1.000 31.12201 ? 194 VAL C CA  1 
ATOM   5637 C  C   . VAL C 1 196 ? 7.83469   5.72390   -31.72537 1.000 29.00908 ? 194 VAL C C   1 
ATOM   5638 O  O   . VAL C 1 196 ? 7.51824   4.60031   -32.14879 1.000 29.54778 ? 194 VAL C O   1 
ATOM   5639 C  CB  . VAL C 1 196 ? 5.96889   7.36136   -31.08500 1.000 28.74249 ? 194 VAL C CB  1 
ATOM   5640 C  CG1 . VAL C 1 196 ? 5.15134   6.74266   -32.20172 1.000 33.03965 ? 194 VAL C CG1 1 
ATOM   5641 C  CG2 . VAL C 1 196 ? 5.06475   7.68803   -29.88957 1.000 28.45450 ? 194 VAL C CG2 1 
ATOM   5642 N  N   . LEU C 1 197 ? 8.88796   6.38066   -32.19510 1.000 28.70255 ? 195 LEU C N   1 
ATOM   5643 C  CA  . LEU C 1 197 ? 9.78032   5.76008   -33.16142 1.000 31.99197 ? 195 LEU C CA  1 
ATOM   5644 C  C   . LEU C 1 197 ? 10.43806  4.52952   -32.55691 1.000 28.92830 ? 195 LEU C C   1 
ATOM   5645 O  O   . LEU C 1 197 ? 10.62922  3.52008   -33.24387 1.000 30.05230 ? 195 LEU C O   1 
ATOM   5646 C  CB  . LEU C 1 197 ? 10.83731  6.77147   -33.61160 1.000 29.90900 ? 195 LEU C CB  1 
ATOM   5647 C  CG  . LEU C 1 197 ? 10.37632  7.84811   -34.58749 1.000 32.20407 ? 195 LEU C CG  1 
ATOM   5648 C  CD1 . LEU C 1 197 ? 11.53068  8.86691   -34.80298 1.000 29.96108 ? 195 LEU C CD1 1 
ATOM   5649 C  CD2 . LEU C 1 197 ? 9.89744   7.22156   -35.90170 1.000 30.35757 ? 195 LEU C CD2 1 
ATOM   5650 N  N   . GLY C 1 198 ? 10.73163  4.57839   -31.25167 1.000 29.73241 ? 196 GLY C N   1 
ATOM   5651 C  CA  . GLY C 1 198 ? 11.22668  3.39338   -30.56068 1.000 26.82275 ? 196 GLY C CA  1 
ATOM   5652 C  C   . GLY C 1 198 ? 10.21666  2.25842   -30.52824 1.000 28.83199 ? 196 GLY C C   1 
ATOM   5653 O  O   . GLY C 1 198 ? 10.57161  1.09868   -30.76071 1.000 27.82809 ? 196 GLY C O   1 
ATOM   5654 N  N   . TRP C 1 199 ? 8.94591   2.56891   -30.24498 1.000 27.99075 ? 197 TRP C N   1 
ATOM   5655 C  CA  . TRP C 1 199 ? 7.91777   1.52465   -30.28161 1.000 27.92338 ? 197 TRP C CA  1 
ATOM   5656 C  C   . TRP C 1 199 ? 7.88387   0.86744   -31.65602 1.000 25.99719 ? 197 TRP C C   1 
ATOM   5657 O  O   . TRP C 1 199 ? 7.91998   -0.36279  -31.77028 1.000 29.48219 ? 197 TRP C O   1 
ATOM   5658 C  CB  . TRP C 1 199 ? 6.51758   2.09284   -29.90352 1.000 29.06172 ? 197 TRP C CB  1 
ATOM   5659 C  CG  . TRP C 1 199 ? 5.48700   0.97793   -29.98233 1.000 26.00734 ? 197 TRP C CG  1 
ATOM   5660 C  CD1 . TRP C 1 199 ? 5.11351   0.12466   -28.97454 1.000 26.43268 ? 197 TRP C CD1 1 
ATOM   5661 C  CD2 . TRP C 1 199 ? 4.82125   0.50808   -31.17078 1.000 26.90554 ? 197 TRP C CD2 1 
ATOM   5662 N  NE1 . TRP C 1 199 ? 4.22603   -0.81108  -29.45961 1.000 27.37326 ? 197 TRP C NE1 1 
ATOM   5663 C  CE2 . TRP C 1 199 ? 4.03020   -0.60028  -30.80026 1.000 27.05841 ? 197 TRP C CE2 1 
ATOM   5664 C  CE3 . TRP C 1 199 ? 4.78253   0.94640   -32.49764 1.000 26.75628 ? 197 TRP C CE3 1 
ATOM   5665 C  CZ2 . TRP C 1 199 ? 3.23349   -1.29225  -31.71669 1.000 25.92585 ? 197 TRP C CZ2 1 
ATOM   5666 C  CZ3 . TRP C 1 199 ? 3.98646   0.25025   -33.40133 1.000 31.86066 ? 197 TRP C CZ3 1 
ATOM   5667 C  CH2 . TRP C 1 199 ? 3.23819   -0.85409  -33.01174 1.000 29.10219 ? 197 TRP C CH2 1 
ATOM   5668 N  N   . LYS C 1 200 ? 7.88778   1.67230   -32.72564 1.000 26.20209 ? 198 LYS C N   1 
ATOM   5669 C  CA  . LYS C 1 200 ? 7.84829   1.09359   -34.07078 1.000 26.90427 ? 198 LYS C CA  1 
ATOM   5670 C  C   . LYS C 1 200 ? 9.02821   0.15752   -34.32116 1.000 28.44864 ? 198 LYS C C   1 
ATOM   5671 O  O   . LYS C 1 200 ? 8.85737   -0.92739  -34.90362 1.000 26.85652 ? 198 LYS C O   1 
ATOM   5672 C  CB  . LYS C 1 200 ? 7.80835   2.20076   -35.11722 1.000 28.60742 ? 198 LYS C CB  1 
ATOM   5673 C  CG  . LYS C 1 200 ? 6.52411   3.05662   -35.07164 1.000 32.48755 ? 198 LYS C CG  1 
ATOM   5674 C  CD  . LYS C 1 200 ? 6.47590   4.06496   -36.21749 1.000 33.92937 ? 198 LYS C CD  1 
ATOM   5675 C  CE  . LYS C 1 200 ? 5.36902   5.10579   -36.01745 1.000 43.22972 ? 198 LYS C CE  1 
ATOM   5676 N  NZ  . LYS C 1 200 ? 4.48987   5.29998   -37.22047 1.000 44.85676 ? 198 LYS C NZ  1 
ATOM   5677 N  N   . GLN C 1 201 ? 10.23057  0.53778   -33.87110 1.000 23.89231 ? 199 GLN C N   1 
ATOM   5678 C  CA  . GLN C 1 201 ? 11.38902  -0.32231  -34.10030 1.000 27.46642 ? 199 GLN C CA  1 
ATOM   5679 C  C   . GLN C 1 201 ? 11.34237  -1.58149  -33.23914 1.000 27.80071 ? 199 GLN C C   1 
ATOM   5680 O  O   . GLN C 1 201 ? 11.68678  -2.66969  -33.70513 1.000 26.82281 ? 199 GLN C O   1 
ATOM   5681 C  CB  . GLN C 1 201 ? 12.67365  0.45314   -33.83048 1.000 28.91231 ? 199 GLN C CB  1 
ATOM   5682 C  CG  . GLN C 1 201 ? 13.01724  1.49070   -34.90221 1.000 33.63914 ? 199 GLN C CG  1 
ATOM   5683 C  CD  . GLN C 1 201 ? 12.90477  0.95413   -36.33746 1.000 35.73773 ? 199 GLN C CD  1 
ATOM   5684 O  OE1 . GLN C 1 201 ? 13.39679  -0.10842  -36.63974 1.000 35.13202 ? 199 GLN C OE1 1 
ATOM   5685 N  NE2 . GLN C 1 201 ? 12.29296  1.74031   -37.22881 1.000 40.65255 ? 199 GLN C NE2 1 
ATOM   5686 N  N   . HIS C 1 202 ? 10.97027  -1.45934  -31.95528 1.000 28.10944 ? 200 HIS C N   1 
ATOM   5687 C  CA  . HIS C 1 202 ? 10.86783  -2.67428  -31.14627 1.000 28.72979 ? 200 HIS C CA  1 
ATOM   5688 C  C   . HIS C 1 202 ? 9.75799   -3.58911  -31.65380 1.000 28.17329 ? 200 HIS C C   1 
ATOM   5689 O  O   . HIS C 1 202 ? 9.86670   -4.81552  -31.57281 1.000 27.05518 ? 200 HIS C O   1 
ATOM   5690 C  CB  . HIS C 1 202 ? 10.63151  -2.29444  -29.67696 1.000 27.77276 ? 200 HIS C CB  1 
ATOM   5691 C  CG  . HIS C 1 202 ? 11.87868  -1.82897  -29.00540 1.000 30.75972 ? 200 HIS C CG  1 
ATOM   5692 N  ND1 . HIS C 1 202 ? 12.92150  -2.68365  -28.71355 1.000 34.74263 ? 200 HIS C ND1 1 
ATOM   5693 C  CD2 . HIS C 1 202 ? 12.26540  -0.59810  -28.58657 1.000 31.45325 ? 200 HIS C CD2 1 
ATOM   5694 C  CE1 . HIS C 1 202 ? 13.90563  -1.99294  -28.16184 1.000 32.39346 ? 200 HIS C CE1 1 
ATOM   5695 N  NE2 . HIS C 1 202 ? 13.52833  -0.73164  -28.06111 1.000 34.37512 ? 200 HIS C NE2 1 
ATOM   5696 N  N   . HIS C 1 203 ? 8.67124   -3.01443  -32.15448 1.000 25.49322 ? 201 HIS C N   1 
ATOM   5697 C  CA  . HIS C 1 203 ? 7.63244   -3.84542  -32.74775 1.000 26.61702 ? 201 HIS C CA  1 
ATOM   5698 C  C   . HIS C 1 203 ? 8.14529   -4.53349  -34.01684 1.000 26.92857 ? 201 HIS C C   1 
ATOM   5699 O  O   . HIS C 1 203 ? 7.76426   -5.67683  -34.31708 1.000 27.56728 ? 201 HIS C O   1 
ATOM   5700 C  CB  . HIS C 1 203 ? 6.40388   -2.96132  -33.02695 1.000 24.78087 ? 201 HIS C CB  1 
ATOM   5701 C  CG  . HIS C 1 203 ? 5.32883   -3.66003  -33.78668 1.000 26.11818 ? 201 HIS C CG  1 
ATOM   5702 N  ND1 . HIS C 1 203 ? 5.25892   -3.64126  -35.16638 1.000 26.83786 ? 201 HIS C ND1 1 
ATOM   5703 C  CD2 . HIS C 1 203 ? 4.29631   -4.42089  -33.36467 1.000 28.00445 ? 201 HIS C CD2 1 
ATOM   5704 C  CE1 . HIS C 1 203 ? 4.22780   -4.36625  -35.55799 1.000 28.90616 ? 201 HIS C CE1 1 
ATOM   5705 N  NE2 . HIS C 1 203 ? 3.63618   -4.85849  -34.48156 1.000 24.59442 ? 201 HIS C NE2 1 
ATOM   5706 N  N   . LEU C 1 204 ? 9.02548   -3.86109  -34.76714 1.000 25.86876 ? 202 LEU C N   1 
ATOM   5707 C  CA  . LEU C 1 204 ? 9.62107   -4.49082  -35.94353 1.000 30.04001 ? 202 LEU C CA  1 
ATOM   5708 C  C   . LEU C 1 204 ? 10.54052  -5.64785  -35.54698 1.000 28.36493 ? 202 LEU C C   1 
ATOM   5709 O  O   . LEU C 1 204 ? 10.46109  -6.74389  -36.10731 1.000 27.45210 ? 202 LEU C O   1 
ATOM   5710 C  CB  . LEU C 1 204 ? 10.37523  -3.42570  -36.74632 1.000 29.67702 ? 202 LEU C CB  1 
ATOM   5711 C  CG  . LEU C 1 204 ? 10.84138  -3.75567  -38.16509 1.000 31.90324 ? 202 LEU C CG  1 
ATOM   5712 C  CD1 . LEU C 1 204 ? 9.72081   -4.37783  -38.99038 1.000 35.48460 ? 202 LEU C CD1 1 
ATOM   5713 C  CD2 . LEU C 1 204 ? 11.36990  -2.48824  -38.85269 1.000 35.94869 ? 202 LEU C CD2 1 
ATOM   5714 N  N   . ILE C 1 205 ? 11.42404  -5.41375  -34.57811 1.000 31.68982 ? 203 ILE C N   1 
ATOM   5715 C  CA  . ILE C 1 205 ? 12.31922  -6.46201  -34.08821 1.000 29.87856 ? 203 ILE C CA  1 
ATOM   5716 C  C   . ILE C 1 205 ? 11.52431  -7.67654  -33.60579 1.000 30.94421 ? 203 ILE C C   1 
ATOM   5717 O  O   . ILE C 1 205 ? 11.86088  -8.82686  -33.90528 1.000 30.07802 ? 203 ILE C O   1 
ATOM   5718 C  CB  . ILE C 1 205 ? 13.22721  -5.90092  -32.97773 1.000 31.29536 ? 203 ILE C CB  1 
ATOM   5719 C  CG1 . ILE C 1 205 ? 14.17217  -4.81195  -33.53521 1.000 33.55945 ? 203 ILE C CG1 1 
ATOM   5720 C  CG2 . ILE C 1 205 ? 13.95442  -7.06341  -32.27903 1.000 29.12618 ? 203 ILE C CG2 1 
ATOM   5721 C  CD1 . ILE C 1 205 ? 14.89541  -3.92810  -32.45091 1.000 27.73339 ? 203 ILE C CD1 1 
ATOM   5722 N  N   . MET C 1 206 ? 10.48671  -7.44001  -32.81068 1.000 33.84507 ? 204 MET C N   1 
ATOM   5723 C  CA  . MET C 1 206 ? 9.52681   -8.49412  -32.46428 1.000 31.93251 ? 204 MET C CA  1 
ATOM   5724 C  C   . MET C 1 206 ? 8.99378   -9.24928  -33.68019 1.000 30.89547 ? 204 MET C C   1 
ATOM   5725 O  O   . MET C 1 206 ? 9.01538   -10.49098 -33.71294 1.000 25.94791 ? 204 MET C O   1 
ATOM   5726 C  CB  . MET C 1 206 ? 8.45387   -7.81672  -31.61727 1.000 30.20484 ? 204 MET C CB  1 
ATOM   5727 C  CG  . MET C 1 206 ? 7.19904   -8.45408  -31.03246 1.000 37.81029 ? 204 MET C CG  1 
ATOM   5728 S  SD  . MET C 1 206 ? 6.22387   -9.33563  -32.22520 1.000 31.55950 ? 204 MET C SD  1 
ATOM   5729 C  CE  . MET C 1 206 ? 5.19884   -7.87659  -32.45998 1.000 33.82858 ? 204 MET C CE  1 
ATOM   5730 N  N   . VAL C 1 207 ? 8.53589   -8.52402  -34.69426 1.000 30.85235 ? 205 VAL C N   1 
ATOM   5731 C  CA  . VAL C 1 207 ? 7.95706   -9.19264  -35.85635 1.000 29.76001 ? 205 VAL C CA  1 
ATOM   5732 C  C   . VAL C 1 207 ? 9.00468   -10.06816 -36.54176 1.000 28.98704 ? 205 VAL C C   1 
ATOM   5733 O  O   . VAL C 1 207 ? 8.71504   -11.19802 -36.96134 1.000 33.22910 ? 205 VAL C O   1 
ATOM   5734 C  CB  . VAL C 1 207 ? 7.34301   -8.14721  -36.81907 1.000 30.83498 ? 205 VAL C CB  1 
ATOM   5735 C  CG1 . VAL C 1 207 ? 7.05185   -8.79316  -38.19155 1.000 34.86765 ? 205 VAL C CG1 1 
ATOM   5736 C  CG2 . VAL C 1 207 ? 6.05899   -7.56208  -36.21406 1.000 28.70990 ? 205 VAL C CG2 1 
ATOM   5737 N  N   . TRP C 1 208 ? 10.25158  -9.58941  -36.60933 1.000 30.02280 ? 206 TRP C N   1 
ATOM   5738 C  CA  . TRP C 1 208 ? 11.33861  -10.36556 -37.20105 1.000 30.64284 ? 206 TRP C CA  1 
ATOM   5739 C  C   . TRP C 1 208 ? 11.55470  -11.67088 -36.45328 1.000 31.71836 ? 206 TRP C C   1 
ATOM   5740 O  O   . TRP C 1 208 ? 11.91287  -12.68983 -37.05672 1.000 31.90432 ? 206 TRP C O   1 
ATOM   5741 C  CB  . TRP C 1 208 ? 12.64444  -9.56069  -37.17154 1.000 32.79025 ? 206 TRP C CB  1 
ATOM   5742 C  CG  . TRP C 1 208 ? 12.65578  -8.37997  -38.08624 1.000 34.05363 ? 206 TRP C CG  1 
ATOM   5743 C  CD1 . TRP C 1 208 ? 11.85072  -8.17057  -39.16912 1.000 34.60141 ? 206 TRP C CD1 1 
ATOM   5744 C  CD2 . TRP C 1 208 ? 13.48397  -7.22174  -37.96878 1.000 32.60876 ? 206 TRP C CD2 1 
ATOM   5745 N  NE1 . TRP C 1 208 ? 12.15154  -6.97534  -39.74896 1.000 35.33146 ? 206 TRP C NE1 1 
ATOM   5746 C  CE2 . TRP C 1 208 ? 13.13756  -6.35763  -39.02482 1.000 35.46391 ? 206 TRP C CE2 1 
ATOM   5747 C  CE3 . TRP C 1 208 ? 14.49932  -6.84056  -37.08017 1.000 34.12746 ? 206 TRP C CE3 1 
ATOM   5748 C  CZ2 . TRP C 1 208 ? 13.77348  -5.11404  -39.23035 1.000 38.05189 ? 206 TRP C CZ2 1 
ATOM   5749 C  CZ3 . TRP C 1 208 ? 15.13837  -5.59615  -37.27501 1.000 35.93536 ? 206 TRP C CZ3 1 
ATOM   5750 C  CH2 . TRP C 1 208 ? 14.75835  -4.74668  -38.34138 1.000 37.96518 ? 206 TRP C CH2 1 
ATOM   5751 N  N   . SER C 1 209 ? 11.36854  -11.65068 -35.12824 1.000 29.20471 ? 207 SER C N   1 
ATOM   5752 C  CA  . SER C 1 209 ? 11.56534  -12.84328 -34.31415 1.000 30.16014 ? 207 SER C CA  1 
ATOM   5753 C  C   . SER C 1 209 ? 10.36070  -13.77655 -34.31019 1.000 29.02460 ? 207 SER C C   1 
ATOM   5754 O  O   . SER C 1 209 ? 10.48519  -14.91394 -33.85755 1.000 29.18822 ? 207 SER C O   1 
ATOM   5755 C  CB  . SER C 1 209 ? 11.92711  -12.43347 -32.87871 1.000 33.31554 ? 207 SER C CB  1 
ATOM   5756 O  OG  . SER C 1 209 ? 10.79647  -12.07007 -32.12513 1.000 32.31243 ? 207 SER C OG  1 
ATOM   5757 N  N   . GLN C 1 210 ? 9.20790   -13.34159 -34.80423 1.000 31.32329 ? 208 GLN C N   1 
ATOM   5758 C  CA  . GLN C 1 210 ? 7.99783   -14.16548 -34.79484 1.000 28.38448 ? 208 GLN C CA  1 
ATOM   5759 C  C   . GLN C 1 210 ? 7.57878   -14.65055 -36.17107 1.000 29.01732 ? 208 GLN C C   1 
ATOM   5760 O  O   . GLN C 1 210 ? 7.07553   -15.77528 -36.30041 1.000 33.68207 ? 208 GLN C O   1 
ATOM   5761 C  CB  . GLN C 1 210 ? 6.84201   -13.37643 -34.16427 1.000 28.71832 ? 208 GLN C CB  1 
ATOM   5762 C  CG  . GLN C 1 210 ? 7.10825   -12.95693 -32.70796 1.000 30.64355 ? 208 GLN C CG  1 
ATOM   5763 C  CD  . GLN C 1 210 ? 6.98631   -14.14902 -31.76091 1.000 31.31175 ? 208 GLN C CD  1 
ATOM   5764 O  OE1 . GLN C 1 210 ? 6.14646   -15.01180 -31.96458 1.000 31.47736 ? 208 GLN C OE1 1 
ATOM   5765 N  NE2 . GLN C 1 210 ? 7.83366   -14.20605 -30.73869 1.000 29.05111 ? 208 GLN C NE2 1 
ATOM   5766 N  N   . LEU C 1 211 ? 7.77791   -13.82651 -37.19985 1.000 27.59884 ? 209 LEU C N   1 
ATOM   5767 C  CA  . LEU C 1 211 ? 7.42041   -14.13186 -38.57592 1.000 31.36592 ? 209 LEU C CA  1 
ATOM   5768 C  C   . LEU C 1 211 ? 8.60604   -14.19148 -39.51411 1.000 32.27379 ? 209 LEU C C   1 
ATOM   5769 O  O   . LEU C 1 211 ? 8.44127   -14.64870 -40.64331 1.000 30.26301 ? 209 LEU C O   1 
ATOM   5770 C  CB  . LEU C 1 211 ? 6.44886   -13.06561 -39.13301 1.000 30.00916 ? 209 LEU C CB  1 
ATOM   5771 C  CG  . LEU C 1 211 ? 5.13505   -12.89255 -38.35899 1.000 30.94066 ? 209 LEU C CG  1 
ATOM   5772 C  CD1 . LEU C 1 211 ? 4.17739   -11.90590 -39.09453 1.000 31.79914 ? 209 LEU C CD1 1 
ATOM   5773 C  CD2 . LEU C 1 211 ? 4.43455   -14.19246 -38.06804 1.000 27.52500 ? 209 LEU C CD2 1 
ATOM   5774 N  N   . GLY C 1 212 ? 9.75803   -13.66487 -39.11823 1.000 37.16569 ? 210 GLY C N   1 
ATOM   5775 C  CA  . GLY C 1 212 ? 10.92561  -13.61975 -39.96710 1.000 34.26583 ? 210 GLY C CA  1 
ATOM   5776 C  C   . GLY C 1 212 ? 11.11173  -12.29183 -40.66868 1.000 35.40927 ? 210 GLY C C   1 
ATOM   5777 O  O   . GLY C 1 212 ? 10.56276  -11.24803 -40.29417 1.000 33.43535 ? 210 GLY C O   1 
ATOM   5778 N  N   . GLY C 1 213 ? 11.93550  -12.33387 -41.70725 1.000 34.48698 ? 211 GLY C N   1 
ATOM   5779 C  CA  . GLY C 1 213 ? 12.19213  -11.13968 -42.48617 1.000 37.10303 ? 211 GLY C CA  1 
ATOM   5780 C  C   . GLY C 1 213 ? 13.28186  -10.21225 -41.98891 1.000 36.48614 ? 211 GLY C C   1 
ATOM   5781 O  O   . GLY C 1 213 ? 13.39829  -9.10865  -42.52269 1.000 37.76943 ? 211 GLY C O   1 
ATOM   5782 N  N   . GLN C 1 214 ? 14.08341  -10.60888 -40.99714 1.000 34.27835 ? 212 GLN C N   1 
ATOM   5783 C  CA  . GLN C 1 214 ? 15.16653  -9.74748  -40.53069 1.000 36.19663 ? 212 GLN C CA  1 
ATOM   5784 C  C   . GLN C 1 214 ? 16.02741  -9.28069  -41.71595 1.000 39.27648 ? 212 GLN C C   1 
ATOM   5785 O  O   . GLN C 1 214 ? 16.50737  -10.11842 -42.48708 1.000 37.93289 ? 212 GLN C O   1 
ATOM   5786 C  CB  . GLN C 1 214 ? 16.02327  -10.48608 -39.50361 1.000 32.93145 ? 212 GLN C CB  1 
ATOM   5787 C  CG  . GLN C 1 214 ? 16.63427  -9.59693  -38.42118 1.000 34.09788 ? 212 GLN C CG  1 
ATOM   5788 C  CD  . GLN C 1 214 ? 17.86083  -8.82065  -38.90510 1.000 34.95129 ? 212 GLN C CD  1 
ATOM   5789 O  OE1 . GLN C 1 214 ? 18.58156  -9.25274  -39.79867 1.000 33.74461 ? 212 GLN C OE1 1 
ATOM   5790 N  NE2 . GLN C 1 214 ? 18.09528  -7.66536  -38.30723 1.000 34.22013 ? 212 GLN C NE2 1 
ATOM   5791 N  N   . PRO C 1 215 ? 16.22666  -7.96298  -41.89943 1.000 38.93206 ? 213 PRO C N   1 
ATOM   5792 C  CA  . PRO C 1 215 ? 16.79722  -7.45935  -43.16876 1.000 40.67912 ? 213 PRO C CA  1 
ATOM   5793 C  C   . PRO C 1 215 ? 18.25447  -7.81050  -43.39929 1.000 44.68556 ? 213 PRO C C   1 
ATOM   5794 O  O   . PRO C 1 215 ? 18.70254  -7.72464  -44.54803 1.000 46.87544 ? 213 PRO C O   1 
ATOM   5795 C  CB  . PRO C 1 215 ? 16.63817  -5.92858  -43.05820 1.000 40.94161 ? 213 PRO C CB  1 
ATOM   5796 C  CG  . PRO C 1 215 ? 15.74130  -5.69392  -41.94712 1.000 41.64916 ? 213 PRO C CG  1 
ATOM   5797 C  CD  . PRO C 1 215 ? 15.91904  -6.84980  -40.98940 1.000 37.00289 ? 213 PRO C CD  1 
ATOM   5798 N  N   . GLY C 1 216 ? 19.02446  -8.14899  -42.36537 1.000 38.93169 ? 214 GLY C N   1 
ATOM   5799 C  CA  . GLY C 1 216 ? 20.37895  -8.61802  -42.61311 1.000 44.23367 ? 214 GLY C CA  1 
ATOM   5800 C  C   . GLY C 1 216 ? 20.41143  -9.89103  -43.44596 1.000 49.36722 ? 214 GLY C C   1 
ATOM   5801 O  O   . GLY C 1 216 ? 21.33031  -10.10103 -44.24261 1.000 56.51454 ? 214 GLY C O   1 
ATOM   5802 N  N   . LEU C 1 217 ? 19.39313  -10.74797 -43.29556 1.000 44.62093 ? 215 LEU C N   1 
ATOM   5803 C  CA  . LEU C 1 217 ? 19.34352  -12.01093 -44.03451 1.000 50.05052 ? 215 LEU C CA  1 
ATOM   5804 C  C   . LEU C 1 217 ? 19.21300  -11.82561 -45.54967 1.000 53.33446 ? 215 LEU C C   1 
ATOM   5805 O  O   . LEU C 1 217 ? 19.37316  -12.80844 -46.28590 1.000 52.54173 ? 215 LEU C O   1 
ATOM   5806 C  CB  . LEU C 1 217 ? 18.18378  -12.88028 -43.52180 1.000 47.97015 ? 215 LEU C CB  1 
ATOM   5807 C  CG  . LEU C 1 217 ? 17.88989  -12.99424 -42.00917 1.000 44.05507 ? 215 LEU C CG  1 
ATOM   5808 C  CD1 . LEU C 1 217 ? 16.53471  -13.66486 -41.76525 1.000 35.39957 ? 215 LEU C CD1 1 
ATOM   5809 C  CD2 . LEU C 1 217 ? 19.00799  -13.76459 -41.28237 1.000 39.83225 ? 215 LEU C CD2 1 
ATOM   5810 N  N   . ARG C 1 218 ? 18.93061  -10.60871 -46.02081 1.000 53.21238 ? 216 ARG C N   1 
ATOM   5811 C  CA  . ARG C 1 218 ? 18.68626  -10.29335 -47.43802 1.000 56.33864 ? 216 ARG C CA  1 
ATOM   5812 C  C   . ARG C 1 218 ? 19.71477  -9.28503  -47.98148 1.000 57.75517 ? 216 ARG C C   1 
ATOM   5813 O  O   . ARG C 1 218 ? 20.90541  -9.58286  -48.11464 1.000 59.13388 ? 216 ARG C O   1 
ATOM   5814 C  CB  . ARG C 1 218 ? 17.27321  -9.70328  -47.62840 1.000 57.61076 ? 216 ARG C CB  1 
ATOM   5815 C  CG  . ARG C 1 218 ? 16.19860  -10.61849 -48.24804 1.000 54.05952 ? 216 ARG C CG  1 
ATOM   5816 C  CD  . ARG C 1 218 ? 16.06512  -11.93319 -47.52668 1.000 53.08567 ? 216 ARG C CD  1 
ATOM   5817 N  NE  . ARG C 1 218 ? 14.83559  -12.65434 -47.86110 1.000 56.69539 ? 216 ARG C NE  1 
ATOM   5818 C  CZ  . ARG C 1 218 ? 13.93218  -13.02903 -46.96102 1.000 50.15386 ? 216 ARG C CZ  1 
ATOM   5819 N  NH1 . ARG C 1 218 ? 14.04349  -12.67368 -45.69300 1.000 40.23638 ? 216 ARG C NH1 1 
ATOM   5820 N  NH2 . ARG C 1 218 ? 12.91873  -13.81924 -47.33515 1.000 48.32908 ? 216 ARG C NH2 1 
ATOM   5821 N  N   . LEU C 1 230 ? 9.12700   -12.56377 -49.16893 1.000 48.15825 ? 228 LEU C N   1 
ATOM   5822 C  CA  . LEU C 1 230 ? 9.12066   -12.19110 -47.75017 1.000 41.71262 ? 228 LEU C CA  1 
ATOM   5823 C  C   . LEU C 1 230 ? 7.84417   -12.70774 -47.11266 1.000 40.60758 ? 228 LEU C C   1 
ATOM   5824 O  O   . LEU C 1 230 ? 6.84281   -12.84981 -47.80271 1.000 42.42147 ? 228 LEU C O   1 
ATOM   5825 C  CB  . LEU C 1 230 ? 9.22331   -10.66325 -47.57032 1.000 45.73032 ? 228 LEU C CB  1 
ATOM   5826 C  CG  . LEU C 1 230 ? 10.64638  -10.07245 -47.57095 1.000 45.88007 ? 228 LEU C CG  1 
ATOM   5827 C  CD1 . LEU C 1 230 ? 11.27679  -10.18391 -46.20062 1.000 46.29212 ? 228 LEU C CD1 1 
ATOM   5828 C  CD2 . LEU C 1 230 ? 11.54656  -10.75515 -48.60040 1.000 50.58901 ? 228 LEU C CD2 1 
ATOM   5829 N  N   . PRO C 1 231 ? 7.87563   -12.99331 -45.78962 1.000 37.08373 ? 229 PRO C N   1 
ATOM   5830 C  CA  . PRO C 1 231 ? 6.63047   -13.28565 -45.06917 1.000 37.77045 ? 229 PRO C CA  1 
ATOM   5831 C  C   . PRO C 1 231 ? 5.56670   -12.21542 -45.26037 1.000 40.36474 ? 229 PRO C C   1 
ATOM   5832 O  O   . PRO C 1 231 ? 5.85707   -11.06514 -45.61363 1.000 41.82513 ? 229 PRO C O   1 
ATOM   5833 C  CB  . PRO C 1 231 ? 7.07460   -13.36237 -43.60022 1.000 36.22783 ? 229 PRO C CB  1 
ATOM   5834 C  CG  . PRO C 1 231 ? 8.50563   -13.79204 -43.66227 1.000 36.25099 ? 229 PRO C CG  1 
ATOM   5835 C  CD  . PRO C 1 231 ? 9.07182   -13.23556 -44.96132 1.000 38.21465 ? 229 PRO C CD  1 
ATOM   5836 N  N   . GLN C 1 232 ? 4.32476   -12.59690 -44.99757 1.000 38.19574 ? 230 GLN C N   1 
ATOM   5837 C  CA  . GLN C 1 232 ? 3.16711   -11.74953 -45.19470 1.000 40.15080 ? 230 GLN C CA  1 
ATOM   5838 C  C   . GLN C 1 232 ? 2.37204   -11.69033 -43.90096 1.000 39.93926 ? 230 GLN C C   1 
ATOM   5839 O  O   . GLN C 1 232 ? 2.35629   -12.64802 -43.12553 1.000 37.71689 ? 230 GLN C O   1 
ATOM   5840 C  CB  . GLN C 1 232 ? 2.29634   -12.27258 -46.32988 1.000 38.97634 ? 230 GLN C CB  1 
ATOM   5841 C  CG  . GLN C 1 232 ? 2.98062   -12.16900 -47.66646 1.000 43.27213 ? 230 GLN C CG  1 
ATOM   5842 C  CD  . GLN C 1 232 ? 2.20360   -12.85273 -48.76822 1.000 49.17020 ? 230 GLN C CD  1 
ATOM   5843 O  OE1 . GLN C 1 232 ? 1.24460   -13.58393 -48.50590 1.000 53.64886 ? 230 GLN C OE1 1 
ATOM   5844 N  NE2 . GLN C 1 232 ? 2.64400   -12.66741 -50.00385 1.000 51.75842 ? 230 GLN C NE2 1 
ATOM   5845 N  N   . SER C 1 233 ? 1.75087   -10.53239 -43.66537 1.000 41.48056 ? 231 SER C N   1 
ATOM   5846 C  CA  . SER C 1 233 ? 0.82352   -10.31526 -42.56245 1.000 39.92547 ? 231 SER C CA  1 
ATOM   5847 C  C   . SER C 1 233 ? -0.46159  -11.10790 -42.77427 1.000 42.77728 ? 231 SER C C   1 
ATOM   5848 O  O   . SER C 1 233 ? -0.71469  -11.64343 -43.85711 1.000 40.47154 ? 231 SER C O   1 
ATOM   5849 C  CB  . SER C 1 233 ? 0.44290   -8.84687  -42.46876 1.000 42.11672 ? 231 SER C CB  1 
ATOM   5850 O  OG  . SER C 1 233 ? -0.48956  -8.53847  -43.49290 1.000 40.47552 ? 231 SER C OG  1 
ATOM   5851 N  N   . LEU C 1 234 ? -1.31769  -11.10709 -41.73812 1.000 38.96334 ? 232 LEU C N   1 
ATOM   5852 C  CA  . LEU C 1 234 ? -2.64388  -11.71553 -41.83650 1.000 42.69284 ? 232 LEU C CA  1 
ATOM   5853 C  C   . LEU C 1 234 ? -3.53717  -11.00967 -42.84983 1.000 42.90700 ? 232 LEU C C   1 
ATOM   5854 O  O   . LEU C 1 234 ? -4.61576  -11.52445 -43.16509 1.000 46.61953 ? 232 LEU C O   1 
ATOM   5855 C  CB  . LEU C 1 234 ? -3.34377  -11.73393 -40.46540 1.000 39.24455 ? 232 LEU C CB  1 
ATOM   5856 C  CG  . LEU C 1 234 ? -2.89090  -12.82970 -39.48310 1.000 41.11855 ? 232 LEU C CG  1 
ATOM   5857 C  CD1 . LEU C 1 234 ? -3.79504  -12.90052 -38.23641 1.000 37.69528 ? 232 LEU C CD1 1 
ATOM   5858 C  CD2 . LEU C 1 234 ? -2.76108  -14.21189 -40.13935 1.000 39.34620 ? 232 LEU C CD2 1 
ATOM   5859 N  N   . GLY C 1 235 ? -3.13433  -9.84871  -43.34204 1.000 44.13461 ? 233 GLY C N   1 
ATOM   5860 C  CA  . GLY C 1 235 ? -3.78540  -9.17989  -44.44423 1.000 48.15600 ? 233 GLY C CA  1 
ATOM   5861 C  C   . GLY C 1 235 ? -3.14865  -9.46353  -45.78417 1.000 49.95112 ? 233 GLY C C   1 
ATOM   5862 O  O   . GLY C 1 235 ? -3.53150  -8.86384  -46.79581 1.000 51.15722 ? 233 GLY C O   1 
ATOM   5863 N  N   . GLY C 1 236 ? -2.16311  -10.35809 -45.81237 1.000 45.09973 ? 234 GLY C N   1 
ATOM   5864 C  CA  . GLY C 1 236 ? -1.47313  -10.72697 -47.03177 1.000 45.25860 ? 234 GLY C CA  1 
ATOM   5865 C  C   . GLY C 1 236 ? -0.41310  -9.75534  -47.48528 1.000 47.34946 ? 234 GLY C C   1 
ATOM   5866 O  O   . GLY C 1 236 ? 0.09360   -9.90096  -48.60161 1.000 44.54780 ? 234 GLY C O   1 
ATOM   5867 N  N   . ARG C 1 237 ? -0.06334  -8.76438  -46.66160 1.000 44.60084 ? 235 ARG C N   1 
ATOM   5868 C  CA  . ARG C 1 237 ? 0.86876   -7.71174  -47.04839 1.000 44.01540 ? 235 ARG C CA  1 
ATOM   5869 C  C   . ARG C 1 237 ? 2.28576   -8.08433  -46.61843 1.000 42.79311 ? 235 ARG C C   1 
ATOM   5870 O  O   . ARG C 1 237 ? 2.50282   -8.53498  -45.48696 1.000 41.74416 ? 235 ARG C O   1 
ATOM   5871 C  CB  . ARG C 1 237 ? 0.44265   -6.37154  -46.43753 1.000 45.17054 ? 235 ARG C CB  1 
ATOM   5872 C  CG  . ARG C 1 237 ? -0.76951  -5.74999  -47.15147 1.000 48.03077 ? 235 ARG C CG  1 
ATOM   5873 C  CD  . ARG C 1 237 ? -1.30062  -4.49476  -46.45959 1.000 47.14218 ? 235 ARG C CD  1 
ATOM   5874 N  NE  . ARG C 1 237 ? -1.83586  -4.78962  -45.13451 1.000 51.23503 ? 235 ARG C NE  1 
ATOM   5875 C  CZ  . ARG C 1 237 ? -3.12559  -4.92420  -44.85075 1.000 50.73073 ? 235 ARG C CZ  1 
ATOM   5876 N  NH1 . ARG C 1 237 ? -4.05798  -4.74994  -45.77430 1.000 51.94473 ? 235 ARG C NH1 1 
ATOM   5877 N  NH2 . ARG C 1 237 ? -3.48630  -5.26293  -43.61285 1.000 48.95776 ? 235 ARG C NH2 1 
ATOM   5878 N  N   . SER C 1 238 ? 3.23358   -7.91847  -47.53809 1.000 43.78371 ? 236 SER C N   1 
ATOM   5879 C  CA  . SER C 1 238 ? 4.63900   -8.20043  -47.26758 1.000 46.06269 ? 236 SER C CA  1 
ATOM   5880 C  C   . SER C 1 238 ? 5.14096   -7.39779  -46.07238 1.000 40.90495 ? 236 SER C C   1 
ATOM   5881 O  O   . SER C 1 238 ? 4.75802   -6.24369  -45.88308 1.000 41.33593 ? 236 SER C O   1 
ATOM   5882 C  CB  . SER C 1 238 ? 5.47363   -7.86690  -48.50584 1.000 40.42015 ? 236 SER C CB  1 
ATOM   5883 O  OG  . SER C 1 238 ? 6.83526   -7.62437  -48.17151 1.000 42.74038 ? 236 SER C OG  1 
ATOM   5884 N  N   . LEU C 1 239 ? 6.03345   -8.00782  -45.28262 1.000 38.53574 ? 237 LEU C N   1 
ATOM   5885 C  CA  . LEU C 1 239 ? 6.63925   -7.31345  -44.15017 1.000 36.71853 ? 237 LEU C CA  1 
ATOM   5886 C  C   . LEU C 1 239 ? 7.42420   -6.08183  -44.58254 1.000 40.27201 ? 237 LEU C C   1 
ATOM   5887 O  O   . LEU C 1 239 ? 7.78016   -5.26110  -43.73351 1.000 37.37661 ? 237 LEU C O   1 
ATOM   5888 C  CB  . LEU C 1 239 ? 7.57056   -8.25334  -43.38519 1.000 39.38012 ? 237 LEU C CB  1 
ATOM   5889 C  CG  . LEU C 1 239 ? 6.92458   -9.39994  -42.61118 1.000 37.60883 ? 237 LEU C CG  1 
ATOM   5890 C  CD1 . LEU C 1 239 ? 7.96584   -10.10723 -41.77480 1.000 38.34085 ? 237 LEU C CD1 1 
ATOM   5891 C  CD2 . LEU C 1 239 ? 5.77458   -8.89911  -41.73071 1.000 35.88204 ? 237 LEU C CD2 1 
ATOM   5892 N  N   . ALA C 1 240 ? 7.72556   -5.93791  -45.87653 1.000 38.50038 ? 238 ALA C N   1 
ATOM   5893 C  CA  . ALA C 1 240 ? 8.42528   -4.73431  -46.32315 1.000 41.49083 ? 238 ALA C CA  1 
ATOM   5894 C  C   . ALA C 1 240 ? 7.58109   -3.47520  -46.11545 1.000 37.03237 ? 238 ALA C C   1 
ATOM   5895 O  O   . ALA C 1 240 ? 8.11811   -2.39442  -45.84280 1.000 34.30152 ? 238 ALA C O   1 
ATOM   5896 C  CB  . ALA C 1 240 ? 8.83846   -4.88352  -47.79822 1.000 38.28365 ? 238 ALA C CB  1 
ATOM   5897 N  N   . THR C 1 241 ? 6.26138   -3.58568  -46.22659 1.000 39.89094 ? 239 THR C N   1 
ATOM   5898 C  CA  . THR C 1 241 ? 5.41957   -2.41051  -46.01250 1.000 36.55403 ? 239 THR C CA  1 
ATOM   5899 C  C   . THR C 1 241 ? 5.41883   -1.98035  -44.54140 1.000 38.02286 ? 239 THR C C   1 
ATOM   5900 O  O   . THR C 1 241 ? 5.45943   -0.78746  -44.23618 1.000 39.87002 ? 239 THR C O   1 
ATOM   5901 C  CB  . THR C 1 241 ? 4.00549   -2.71619  -46.51474 1.000 42.77713 ? 239 THR C CB  1 
ATOM   5902 O  OG1 . THR C 1 241 ? 3.42982   -3.74861  -45.70657 1.000 49.90992 ? 239 THR C OG1 1 
ATOM   5903 C  CG2 . THR C 1 241 ? 4.05455   -3.24420  -47.93922 1.000 38.49515 ? 239 THR C CG2 1 
ATOM   5904 N  N   . LEU C 1 242 ? 5.40711   -2.93425  -43.61121 1.000 38.89095 ? 240 LEU C N   1 
ATOM   5905 C  CA  . LEU C 1 242 ? 5.54808   -2.58830  -42.19887 1.000 35.67690 ? 240 LEU C CA  1 
ATOM   5906 C  C   . LEU C 1 242 ? 6.85819   -1.83889  -41.94717 1.000 35.34970 ? 240 LEU C C   1 
ATOM   5907 O  O   . LEU C 1 242 ? 6.88015   -0.79397  -41.28792 1.000 34.88349 ? 240 LEU C O   1 
ATOM   5908 C  CB  . LEU C 1 242 ? 5.48026   -3.86945  -41.35079 1.000 34.18206 ? 240 LEU C CB  1 
ATOM   5909 C  CG  . LEU C 1 242 ? 5.76905   -3.65952  -39.86825 1.000 32.33011 ? 240 LEU C CG  1 
ATOM   5910 C  CD1 . LEU C 1 242 ? 4.59981   -2.93557  -39.22899 1.000 32.81918 ? 240 LEU C CD1 1 
ATOM   5911 C  CD2 . LEU C 1 242 ? 6.05722   -4.94526  -39.14323 1.000 33.50668 ? 240 LEU C CD2 1 
ATOM   5912 N  N   . GLU C 1 243 ? 7.97205   -2.36741  -42.46361 1.000 40.00593 ? 241 GLU C N   1 
ATOM   5913 C  CA  . GLU C 1 243 ? 9.25829   -1.69454  -42.28534 1.000 37.82882 ? 241 GLU C CA  1 
ATOM   5914 C  C   . GLU C 1 243 ? 9.23194   -0.28217  -42.84980 1.000 39.16127 ? 241 GLU C C   1 
ATOM   5915 O  O   . GLU C 1 243 ? 9.75766   0.66381   -42.23123 1.000 35.08158 ? 241 GLU C O   1 
ATOM   5916 C  CB  . GLU C 1 243 ? 10.37093  -2.53622  -42.92466 1.000 39.77452 ? 241 GLU C CB  1 
ATOM   5917 C  CG  . GLU C 1 243 ? 11.75907  -2.23868  -42.38011 1.000 41.32830 ? 241 GLU C CG  1 
ATOM   5918 C  CD  . GLU C 1 243 ? 12.84370  -2.84453  -43.24331 1.000 45.72010 ? 241 GLU C CD  1 
ATOM   5919 O  OE1 . GLU C 1 243 ? 12.52640  -3.80558  -43.96095 1.000 45.40349 ? 241 GLU C OE1 1 
ATOM   5920 O  OE2 . GLU C 1 243 ? 13.99495  -2.35070  -43.23665 1.000 47.99396 ? 241 GLU C OE2 1 
ATOM   5921 N  N   . ALA C 1 244 ? 8.59395   -0.10625  -44.00642 1.000 38.08355 ? 242 ALA C N   1 
ATOM   5922 C  CA  . ALA C 1 244 ? 8.53420   1.22956   -44.60138 1.000 42.10692 ? 242 ALA C CA  1 
ATOM   5923 C  C   . ALA C 1 244 ? 7.77288   2.20291   -43.69963 1.000 40.37454 ? 242 ALA C C   1 
ATOM   5924 O  O   . ALA C 1 244 ? 8.21487   3.33783   -43.48068 1.000 40.52033 ? 242 ALA C O   1 
ATOM   5925 C  CB  . ALA C 1 244 ? 7.90925   1.15855   -45.99705 1.000 37.17908 ? 242 ALA C CB  1 
ATOM   5926 N  N   . ARG C 1 245 ? 6.61653   1.79170   -43.17761 1.000 37.95997 ? 243 ARG C N   1 
ATOM   5927 C  CA  . ARG C 1 245 ? 5.89247   2.69997   -42.29795 1.000 38.57700 ? 243 ARG C CA  1 
ATOM   5928 C  C   . ARG C 1 245 ? 6.54777   2.87654   -40.94061 1.000 39.27420 ? 243 ARG C C   1 
ATOM   5929 O  O   . ARG C 1 245 ? 6.18476   3.82020   -40.21977 1.000 38.11759 ? 243 ARG C O   1 
ATOM   5930 C  CB  . ARG C 1 245 ? 4.41167   2.29276   -42.12500 1.000 40.21588 ? 243 ARG C CB  1 
ATOM   5931 C  CG  . ARG C 1 245 ? 3.72388   1.89013   -43.40394 1.000 40.28463 ? 243 ARG C CG  1 
ATOM   5932 C  CD  . ARG C 1 245 ? 2.28641   1.46095   -43.21253 1.000 41.78904 ? 243 ARG C CD  1 
ATOM   5933 N  NE  . ARG C 1 245 ? 2.13976   0.35000   -42.28570 1.000 45.05985 ? 243 ARG C NE  1 
ATOM   5934 C  CZ  . ARG C 1 245 ? 1.93052   -0.89850  -42.68590 1.000 46.21380 ? 243 ARG C CZ  1 
ATOM   5935 N  NH1 . ARG C 1 245 ? 1.81381   -1.19888  -43.97316 1.000 47.23837 ? 243 ARG C NH1 1 
ATOM   5936 N  NH2 . ARG C 1 245 ? 1.84660   -1.87166  -41.77732 1.000 40.46303 ? 243 ARG C NH2 1 
ATOM   5937 N  N   . SER C 1 246 ? 7.51421   2.02852   -40.59997 1.000 35.67697 ? 244 SER C N   1 
ATOM   5938 C  CA  . SER C 1 246 ? 8.18172   2.09291   -39.31013 1.000 34.64663 ? 244 SER C CA  1 
ATOM   5939 C  C   . SER C 1 246 ? 8.98879   3.36650   -39.14212 1.000 37.95655 ? 244 SER C C   1 
ATOM   5940 O  O   . SER C 1 246 ? 9.36072   3.70798   -38.01475 1.000 37.49593 ? 244 SER C O   1 
ATOM   5941 C  CB  . SER C 1 246 ? 9.09022   0.86164   -39.13261 1.000 38.00934 ? 244 SER C CB  1 
ATOM   5942 O  OG  . SER C 1 246 ? 10.43471  1.12011   -39.53031 1.000 39.11929 ? 244 SER C OG  1 
ATOM   5943 N  N   . GLN C 1 247 ? 9.26556   4.09279   -40.21621 1.000 31.73609 ? 245 GLN C N   1 
ATOM   5944 C  CA  . GLN C 1 247 ? 10.14549  5.23063   -40.06515 1.000 37.99028 ? 245 GLN C CA  1 
ATOM   5945 C  C   . GLN C 1 247 ? 9.34109   6.54330   -40.06408 1.000 34.82536 ? 245 GLN C C   1 
ATOM   5946 O  O   . GLN C 1 247 ? 9.93015   7.62231   -40.05210 1.000 37.36219 ? 245 GLN C O   1 
ATOM   5947 C  CB  . GLN C 1 247 ? 11.18255  5.20127   -41.18099 1.000 44.58305 ? 245 GLN C CB  1 
ATOM   5948 C  CG  . GLN C 1 247 ? 12.33374  4.19171   -40.86665 1.000 43.99406 ? 245 GLN C CG  1 
ATOM   5949 C  CD  . GLN C 1 247 ? 13.21377  3.93215   -42.08791 1.000 47.33107 ? 245 GLN C CD  1 
ATOM   5950 O  OE1 . GLN C 1 247 ? 12.71528  3.84587   -43.21730 1.000 46.43768 ? 245 GLN C OE1 1 
ATOM   5951 N  NE2 . GLN C 1 247 ? 14.49776  3.66212   -41.84668 1.000 42.75383 ? 245 GLN C NE2 1 
ATOM   5952 N  N   . LEU C 1 248 ? 8.00137   6.46032   -40.03217 1.000 34.82498 ? 246 LEU C N   1 
ATOM   5953 C  CA  . LEU C 1 248 ? 7.13969   7.63629   -40.07624 1.000 36.06060 ? 246 LEU C CA  1 
ATOM   5954 C  C   . LEU C 1 248 ? 6.98413   8.22516   -38.68000 1.000 37.75681 ? 246 LEU C C   1 
ATOM   5955 O  O   . LEU C 1 248 ? 6.50030   7.55055   -37.77135 1.000 35.29182 ? 246 LEU C O   1 
ATOM   5956 C  CB  . LEU C 1 248 ? 5.77129   7.28576   -40.64522 1.000 35.35074 ? 246 LEU C CB  1 
ATOM   5957 C  CG  . LEU C 1 248 ? 5.79203   6.81649   -42.09695 1.000 39.77513 ? 246 LEU C CG  1 
ATOM   5958 C  CD1 . LEU C 1 248 ? 4.38495   6.43211   -42.52945 1.000 42.54202 ? 246 LEU C CD1 1 
ATOM   5959 C  CD2 . LEU C 1 248 ? 6.34905   7.93210   -42.96964 1.000 38.01571 ? 246 LEU C CD2 1 
ATOM   5960 N  N   . ALA C 1 249 ? 7.38512   9.48073   -38.52066 1.000 34.13950 ? 247 ALA C N   1 
ATOM   5961 C  CA  . ALA C 1 249 ? 7.29043   10.19605  -37.25922 1.000 34.87593 ? 247 ALA C CA  1 
ATOM   5962 C  C   . ALA C 1 249 ? 5.91783   10.83860  -37.09087 1.000 36.63250 ? 247 ALA C C   1 
ATOM   5963 O  O   . ALA C 1 249 ? 5.18546   11.06155  -38.05963 1.000 34.04277 ? 247 ALA C O   1 
ATOM   5964 C  CB  . ALA C 1 249 ? 8.35776   11.29535  -37.18114 1.000 35.66696 ? 247 ALA C CB  1 
ATOM   5965 N  N   . LEU C 1 250 ? 5.61051   11.17987  -35.82915 1.000 35.28024 ? 248 LEU C N   1 
ATOM   5966 C  CA  . LEU C 1 250 ? 4.45620   12.01632  -35.50331 1.000 35.30619 ? 248 LEU C CA  1 
ATOM   5967 C  C   . LEU C 1 250 ? 4.62098   13.43466  -36.02032 1.000 35.77832 ? 248 LEU C C   1 
ATOM   5968 O  O   . LEU C 1 250 ? 3.66054   14.02257  -36.53858 1.000 34.30693 ? 248 LEU C O   1 
ATOM   5969 C  CB  . LEU C 1 250 ? 4.25240   12.07933  -33.98060 1.000 31.86146 ? 248 LEU C CB  1 
ATOM   5970 C  CG  . LEU C 1 250 ? 3.92968   10.72766  -33.31642 1.000 35.61228 ? 248 LEU C CG  1 
ATOM   5971 C  CD1 . LEU C 1 250 ? 3.71772   10.92343  -31.83109 1.000 34.16737 ? 248 LEU C CD1 1 
ATOM   5972 C  CD2 . LEU C 1 250 ? 2.69264   10.07677  -33.92572 1.000 33.66780 ? 248 LEU C CD2 1 
ATOM   5973 N  N   . PHE C 1 251 ? 5.81067   14.02640  -35.81676 1.000 32.56988 ? 249 PHE C N   1 
ATOM   5974 C  CA  . PHE C 1 251 ? 6.08653   15.42559  -36.10868 1.000 29.89167 ? 249 PHE C CA  1 
ATOM   5975 C  C   . PHE C 1 251 ? 7.27546   15.54793  -37.06055 1.000 33.19940 ? 249 PHE C C   1 
ATOM   5976 O  O   . PHE C 1 251 ? 8.34972   16.03206  -36.67063 1.000 30.56575 ? 249 PHE C O   1 
ATOM   5977 C  CB  . PHE C 1 251 ? 6.36702   16.21099  -34.82488 1.000 33.87146 ? 249 PHE C CB  1 
ATOM   5978 C  CG  . PHE C 1 251 ? 5.45991   15.84918  -33.65012 1.000 31.96969 ? 249 PHE C CG  1 
ATOM   5979 C  CD1 . PHE C 1 251 ? 4.07492   15.95647  -33.75097 1.000 28.78178 ? 249 PHE C CD1 1 
ATOM   5980 C  CD2 . PHE C 1 251 ? 6.01056   15.42996  -32.44198 1.000 29.09194 ? 249 PHE C CD2 1 
ATOM   5981 C  CE1 . PHE C 1 251 ? 3.25447   15.64725  -32.66698 1.000 33.51093 ? 249 PHE C CE1 1 
ATOM   5982 C  CE2 . PHE C 1 251 ? 5.20242   15.11831  -31.34133 1.000 29.64161 ? 249 PHE C CE2 1 
ATOM   5983 C  CZ  . PHE C 1 251 ? 3.81891   15.21655  -31.45649 1.000 32.22051 ? 249 PHE C CZ  1 
ATOM   5984 N  N   . PRO C 1 252 ? 7.10523   15.16922  -38.33053 1.000 33.96197 ? 250 PRO C N   1 
ATOM   5985 C  CA  . PRO C 1 252 ? 8.25315   15.21234  -39.25916 1.000 34.00090 ? 250 PRO C CA  1 
ATOM   5986 C  C   . PRO C 1 252 ? 8.94043   16.57680  -39.30563 1.000 35.00034 ? 250 PRO C C   1 
ATOM   5987 O  O   . PRO C 1 252 ? 10.15950  16.65427  -39.51596 1.000 35.54470 ? 250 PRO C O   1 
ATOM   5988 C  CB  . PRO C 1 252 ? 7.63941   14.84296  -40.61617 1.000 34.87570 ? 250 PRO C CB  1 
ATOM   5989 C  CG  . PRO C 1 252 ? 6.23414   14.48349  -40.38202 1.000 36.22011 ? 250 PRO C CG  1 
ATOM   5990 C  CD  . PRO C 1 252 ? 5.89988   14.57617  -38.92869 1.000 36.54044 ? 250 PRO C CD  1 
ATOM   5991 N  N   . GLU C 1 253 ? 8.19226   17.65716  -39.08149 1.000 31.43152 ? 251 GLU C N   1 
ATOM   5992 C  CA  . GLU C 1 253 ? 8.76559   19.00512  -39.12249 1.000 32.57520 ? 251 GLU C CA  1 
ATOM   5993 C  C   . GLU C 1 253 ? 9.85369   19.21278  -38.07545 1.000 30.46313 ? 251 GLU C C   1 
ATOM   5994 O  O   . GLU C 1 253 ? 10.78638  19.99065  -38.30784 1.000 29.82044 ? 251 GLU C O   1 
ATOM   5995 C  CB  . GLU C 1 253 ? 7.64667   20.01859  -38.93467 1.000 36.74235 ? 251 GLU C CB  1 
ATOM   5996 C  CG  . GLU C 1 253 ? 6.65317   19.99885  -40.06769 1.000 41.26948 ? 251 GLU C CG  1 
ATOM   5997 C  CD  . GLU C 1 253 ? 5.35695   19.28900  -39.71695 1.000 45.98549 ? 251 GLU C CD  1 
ATOM   5998 O  OE1 . GLU C 1 253 ? 5.34731   18.34911  -38.84958 1.000 43.20689 ? 251 GLU C OE1 1 
ATOM   5999 O  OE2 . GLU C 1 253 ? 4.32447   19.71760  -40.29223 1.000 54.36480 ? 251 GLU C OE2 1 
ATOM   6000 N  N   . LEU C 1 254 ? 9.75074   18.54009  -36.91880 1.000 29.57901 ? 252 LEU C N   1 
ATOM   6001 C  CA  . LEU C 1 254 ? 10.79575  18.63740  -35.90111 1.000 30.58965 ? 252 LEU C CA  1 
ATOM   6002 C  C   . LEU C 1 254 ? 12.09131  17.99923  -36.37998 1.000 31.18968 ? 252 LEU C C   1 
ATOM   6003 O  O   . LEU C 1 254 ? 13.17925  18.52448  -36.12405 1.000 29.70515 ? 252 LEU C O   1 
ATOM   6004 C  CB  . LEU C 1 254 ? 10.35018  17.94717  -34.59736 1.000 33.20964 ? 252 LEU C CB  1 
ATOM   6005 C  CG  . LEU C 1 254 ? 9.50542   18.70677  -33.58973 1.000 39.69498 ? 252 LEU C CG  1 
ATOM   6006 C  CD1 . LEU C 1 254 ? 9.50388   17.93312  -32.25418 1.000 35.09698 ? 252 LEU C CD1 1 
ATOM   6007 C  CD2 . LEU C 1 254 ? 10.01373  20.13490  -33.41493 1.000 37.87118 ? 252 LEU C CD2 1 
ATOM   6008 N  N   . TRP C 1 255 ? 11.99507  16.82077  -37.00641 1.000 29.09769 ? 253 TRP C N   1 
ATOM   6009 C  CA  . TRP C 1 255 ? 13.17437  16.18521  -37.58326 1.000 31.79844 ? 253 TRP C CA  1 
ATOM   6010 C  C   . TRP C 1 255 ? 13.69701  16.97402  -38.76792 1.000 29.96266 ? 253 TRP C C   1 
ATOM   6011 O  O   . TRP C 1 255 ? 14.90925  16.97860  -39.01635 1.000 29.77979 ? 253 TRP C O   1 
ATOM   6012 C  CB  . TRP C 1 255 ? 12.85254  14.73619  -37.99461 1.000 29.50485 ? 253 TRP C CB  1 
ATOM   6013 C  CG  . TRP C 1 255 ? 12.28061  13.98017  -36.83151 1.000 32.23764 ? 253 TRP C CG  1 
ATOM   6014 C  CD1 . TRP C 1 255 ? 10.95588  13.86910  -36.49941 1.000 31.45955 ? 253 TRP C CD1 1 
ATOM   6015 C  CD2 . TRP C 1 255 ? 13.01148  13.28816  -35.80347 1.000 30.29331 ? 253 TRP C CD2 1 
ATOM   6016 N  NE1 . TRP C 1 255 ? 10.81659  13.12907  -35.33760 1.000 33.41539 ? 253 TRP C NE1 1 
ATOM   6017 C  CE2 . TRP C 1 255 ? 12.06278  12.77058  -34.88993 1.000 32.00664 ? 253 TRP C CE2 1 
ATOM   6018 C  CE3 . TRP C 1 255 ? 14.36657  13.07204  -35.56065 1.000 29.34430 ? 253 TRP C CE3 1 
ATOM   6019 C  CZ2 . TRP C 1 255 ? 12.43081  12.04676  -33.75793 1.000 31.91765 ? 253 TRP C CZ2 1 
ATOM   6020 C  CZ3 . TRP C 1 255 ? 14.73211  12.33648  -34.43212 1.000 32.07280 ? 253 TRP C CZ3 1 
ATOM   6021 C  CH2 . TRP C 1 255 ? 13.77454  11.83205  -33.55495 1.000 31.49266 ? 253 TRP C CH2 1 
ATOM   6022 N  N   . ARG C 1 256 ? 12.80755  17.64319  -39.51273 1.000 30.69150 ? 254 ARG C N   1 
ATOM   6023 C  CA  . ARG C 1 256 ? 13.29648  18.51845  -40.58239 1.000 31.64439 ? 254 ARG C CA  1 
ATOM   6024 C  C   . ARG C 1 256 ? 14.05760  19.70688  -40.01431 1.000 31.11435 ? 254 ARG C C   1 
ATOM   6025 O  O   . ARG C 1 256 ? 15.05212  20.15599  -40.60466 1.000 31.06245 ? 254 ARG C O   1 
ATOM   6026 C  CB  . ARG C 1 256 ? 12.14946  18.99210  -41.47392 1.000 35.32449 ? 254 ARG C CB  1 
ATOM   6027 C  CG  . ARG C 1 256 ? 12.51548  18.94034  -42.98075 1.000 45.08077 ? 254 ARG C CG  1 
ATOM   6028 C  CD  . ARG C 1 256 ? 11.38794  19.46488  -43.86122 1.000 46.87702 ? 254 ARG C CD  1 
ATOM   6029 N  NE  . ARG C 1 256 ? 10.16550  18.67042  -43.71177 1.000 46.82656 ? 254 ARG C NE  1 
ATOM   6030 C  CZ  . ARG C 1 256 ? 9.94281   17.49915  -44.29833 1.000 52.74627 ? 254 ARG C CZ  1 
ATOM   6031 N  NH1 . ARG C 1 256 ? 10.84422  16.93514  -45.10138 1.000 47.99788 ? 254 ARG C NH1 1 
ATOM   6032 N  NH2 . ARG C 1 256 ? 8.78438   16.87666  -44.08126 1.000 52.31070 ? 254 ARG C NH2 1 
ATOM   6033 N  N   . ALA C 1 257 ? 13.61752  20.24214  -38.86095 1.000 28.41033 ? 255 ALA C N   1 
ATOM   6034 C  CA  . ALA C 1 257 ? 14.35997  21.37052  -38.30886 1.000 28.42086 ? 255 ALA C CA  1 
ATOM   6035 C  C   . ALA C 1 257 ? 15.70295  20.91964  -37.75577 1.000 28.06523 ? 255 ALA C C   1 
ATOM   6036 O  O   . ALA C 1 257 ? 16.67353  21.68625  -37.78559 1.000 29.95131 ? 255 ALA C O   1 
ATOM   6037 C  CB  . ALA C 1 257 ? 13.53875  22.09051  -37.23192 1.000 30.48795 ? 255 ALA C CB  1 
ATOM   6038 N  N   . ALA C 1 258 ? 15.77906  19.68652  -37.23332 1.000 29.01922 ? 256 ALA C N   1 
ATOM   6039 C  CA  . ALA C 1 258 ? 17.07155  19.14430  -36.81430 1.000 27.90344 ? 256 ALA C CA  1 
ATOM   6040 C  C   . ALA C 1 258 ? 18.04544  19.08426  -37.99024 1.000 29.16509 ? 256 ALA C C   1 
ATOM   6041 O  O   . ALA C 1 258 ? 19.20343  19.50433  -37.88436 1.000 30.32164 ? 256 ALA C O   1 
ATOM   6042 C  CB  . ALA C 1 258 ? 16.87572  17.74055  -36.20583 1.000 28.25759 ? 256 ALA C CB  1 
ATOM   6043 N  N   . GLU C 1 259 ? 17.60339  18.54852  -39.12327 1.000 28.88175 ? 257 GLU C N   1 
ATOM   6044 C  CA  . GLU C 1 259 ? 18.51460  18.48625  -40.26784 1.000 29.12845 ? 257 GLU C CA  1 
ATOM   6045 C  C   . GLU C 1 259 ? 18.88400  19.88610  -40.74845 1.000 32.23555 ? 257 GLU C C   1 
ATOM   6046 O  O   . GLU C 1 259 ? 20.02658  20.14760  -41.15260 1.000 29.97754 ? 257 GLU C O   1 
ATOM   6047 C  CB  . GLU C 1 259 ? 17.88698  17.68236  -41.40007 1.000 32.31030 ? 257 GLU C CB  1 
ATOM   6048 C  CG  . GLU C 1 259 ? 18.80532  17.63022  -42.59369 1.000 31.16346 ? 257 GLU C CG  1 
ATOM   6049 C  CD  . GLU C 1 259 ? 18.40653  16.62394  -43.62112 1.000 35.77966 ? 257 GLU C CD  1 
ATOM   6050 O  OE1 . GLU C 1 259 ? 17.86218  15.53667  -43.24882 1.000 36.16322 ? 257 GLU C OE1 1 
ATOM   6051 O  OE2 . GLU C 1 259 ? 18.64620  16.93511  -44.81820 1.000 35.13138 ? 257 GLU C OE2 1 
ATOM   6052 N  N   . ASP C 1 260 ? 17.91440  20.80189  -40.69011 1.000 32.23721 ? 258 ASP C N   1 
ATOM   6053 C  CA  . ASP C 1 260 ? 18.12259  22.19770  -41.04118 1.000 30.20572 ? 258 ASP C CA  1 
ATOM   6054 C  C   . ASP C 1 260 ? 19.26374  22.79257  -40.23296 1.000 31.00976 ? 258 ASP C C   1 
ATOM   6055 O  O   . ASP C 1 260 ? 20.13136  23.49311  -40.77081 1.000 28.37842 ? 258 ASP C O   1 
ATOM   6056 C  CB  . ASP C 1 260 ? 16.82037  22.92685  -40.75284 1.000 32.37127 ? 258 ASP C CB  1 
ATOM   6057 C  CG  . ASP C 1 260 ? 16.43040  23.84785  -41.80620 1.000 34.09796 ? 258 ASP C CG  1 
ATOM   6058 O  OD1 . ASP C 1 260 ? 16.76302  23.56528  -42.95215 1.000 40.63769 ? 258 ASP C OD1 1 
ATOM   6059 O  OD2 . ASP C 1 260 ? 15.68118  24.80907  -41.51239 1.000 40.17398 ? 258 ASP C OD2 1 
ATOM   6060 N  N   . ALA C 1 261 ? 19.29770  22.48000  -38.93704 1.000 31.44232 ? 259 ALA C N   1 
ATOM   6061 C  CA  . ALA C 1 261 ? 20.35246  22.98776  -38.06865 1.000 30.51560 ? 259 ALA C CA  1 
ATOM   6062 C  C   . ALA C 1 261 ? 21.69989  22.42256  -38.47791 1.000 29.25817 ? 259 ALA C C   1 
ATOM   6063 O  O   . ALA C 1 261 ? 22.71389  23.12147  -38.41946 1.000 30.72594 ? 259 ALA C O   1 
ATOM   6064 C  CB  . ALA C 1 261 ? 20.04919  22.63360  -36.60482 1.000 28.81229 ? 259 ALA C CB  1 
ATOM   6065 N  N   . TYR C 1 262 ? 21.73314  21.15095  -38.88641 1.000 29.48086 ? 260 TYR C N   1 
ATOM   6066 C  CA  . TYR C 1 262 ? 22.98089  20.57700  -39.35868 1.000 28.62699 ? 260 TYR C CA  1 
ATOM   6067 C  C   . TYR C 1 262 ? 23.50818  21.36624  -40.55173 1.000 30.04157 ? 260 TYR C C   1 
ATOM   6068 O  O   . TYR C 1 262 ? 24.69328  21.71211  -40.60980 1.000 28.40634 ? 260 TYR C O   1 
ATOM   6069 C  CB  . TYR C 1 262 ? 22.77794  19.09908  -39.72913 1.000 32.30489 ? 260 TYR C CB  1 
ATOM   6070 C  CG  . TYR C 1 262 ? 23.92341  18.50889  -40.50804 1.000 31.64212 ? 260 TYR C CG  1 
ATOM   6071 C  CD1 . TYR C 1 262 ? 25.00506  17.91918  -39.85076 1.000 30.49106 ? 260 TYR C CD1 1 
ATOM   6072 C  CD2 . TYR C 1 262 ? 23.94342  18.56031  -41.90809 1.000 32.37612 ? 260 TYR C CD2 1 
ATOM   6073 C  CE1 . TYR C 1 262 ? 26.07338  17.38283  -40.56926 1.000 32.49930 ? 260 TYR C CE1 1 
ATOM   6074 C  CE2 . TYR C 1 262 ? 25.00634  18.02935  -42.63030 1.000 33.04629 ? 260 TYR C CE2 1 
ATOM   6075 C  CZ  . TYR C 1 262 ? 26.06279  17.43972  -41.96042 1.000 36.16338 ? 260 TYR C CZ  1 
ATOM   6076 O  OH  . TYR C 1 262 ? 27.11393  16.90586  -42.67399 1.000 37.09287 ? 260 TYR C OH  1 
ATOM   6077 N  N   . TRP C 1 263 ? 22.63735  21.65672  -41.51771 1.000 27.96649 ? 261 TRP C N   1 
ATOM   6078 C  CA  . TRP C 1 263 ? 23.10508  22.35291  -42.71735 1.000 30.79939 ? 261 TRP C CA  1 
ATOM   6079 C  C   . TRP C 1 263 ? 23.48329  23.79475  -42.41230 1.000 33.01188 ? 261 TRP C C   1 
ATOM   6080 O  O   . TRP C 1 263 ? 24.49354  24.29520  -42.92813 1.000 32.04499 ? 261 TRP C O   1 
ATOM   6081 C  CB  . TRP C 1 263 ? 22.04020  22.31606  -43.80161 1.000 31.59788 ? 261 TRP C CB  1 
ATOM   6082 C  CG  . TRP C 1 263 ? 21.83613  20.93935  -44.34615 1.000 31.90000 ? 261 TRP C CG  1 
ATOM   6083 C  CD1 . TRP C 1 263 ? 20.70110  20.18176  -44.24365 1.000 33.42142 ? 261 TRP C CD1 1 
ATOM   6084 C  CD2 . TRP C 1 263 ? 22.78759  20.14988  -45.07932 1.000 36.02141 ? 261 TRP C CD2 1 
ATOM   6085 N  NE1 . TRP C 1 263 ? 20.88726  18.96775  -44.87694 1.000 35.55805 ? 261 TRP C NE1 1 
ATOM   6086 C  CE2 . TRP C 1 263 ? 22.15864  18.91430  -45.38262 1.000 35.64722 ? 261 TRP C CE2 1 
ATOM   6087 C  CE3 . TRP C 1 263 ? 24.10686  20.35817  -45.49809 1.000 35.41654 ? 261 TRP C CE3 1 
ATOM   6088 C  CZ2 . TRP C 1 263 ? 22.80091  17.88978  -46.10959 1.000 38.54965 ? 261 TRP C CZ2 1 
ATOM   6089 C  CZ3 . TRP C 1 263 ? 24.74987  19.33600  -46.21789 1.000 42.32747 ? 261 TRP C CZ3 1 
ATOM   6090 C  CH2 . TRP C 1 263 ? 24.09022  18.11372  -46.50613 1.000 39.54402 ? 261 TRP C CH2 1 
ATOM   6091 N  N   . LEU C 1 264 ? 22.68889  24.47314  -41.57384 1.000 31.99122 ? 262 LEU C N   1 
ATOM   6092 C  CA  . LEU C 1 264 ? 22.93810  25.89187  -41.28857 1.000 32.86967 ? 262 LEU C CA  1 
ATOM   6093 C  C   . LEU C 1 264 ? 24.12743  26.07920  -40.37698 1.000 35.21564 ? 262 LEU C C   1 
ATOM   6094 O  O   . LEU C 1 264 ? 24.84695  27.06126  -40.52014 1.000 31.04650 ? 262 LEU C O   1 
ATOM   6095 C  CB  . LEU C 1 264 ? 21.71155  26.56290  -40.66721 1.000 30.01679 ? 262 LEU C CB  1 
ATOM   6096 C  CG  . LEU C 1 264 ? 20.46733  26.51473  -41.54144 1.000 33.04698 ? 262 LEU C CG  1 
ATOM   6097 C  CD1 . LEU C 1 264 ? 19.22069  26.90641  -40.80830 1.000 29.28873 ? 262 LEU C CD1 1 
ATOM   6098 C  CD2 . LEU C 1 264 ? 20.74221  27.53202  -42.67342 1.000 36.16464 ? 262 LEU C CD2 1 
ATOM   6099 N  N   . LEU C 1 265 ? 24.36997  25.14886  -39.44884 1.000 30.73739 ? 263 LEU C N   1 
ATOM   6100 C  CA  . LEU C 1 265 ? 25.33758  25.41966  -38.40411 1.000 31.08813 ? 263 LEU C CA  1 
ATOM   6101 C  C   . LEU C 1 265 ? 26.56240  24.53780  -38.46106 1.000 32.15767 ? 263 LEU C C   1 
ATOM   6102 O  O   . LEU C 1 265 ? 27.59906  24.93332  -37.91681 1.000 31.47435 ? 263 LEU C O   1 
ATOM   6103 C  CB  . LEU C 1 265 ? 24.69064  25.28669  -37.01056 1.000 32.69507 ? 263 LEU C CB  1 
ATOM   6104 C  CG  . LEU C 1 265 ? 23.39053  26.05748  -36.79487 1.000 28.42559 ? 263 LEU C CG  1 
ATOM   6105 C  CD1 . LEU C 1 265 ? 22.75771  25.60641  -35.48561 1.000 30.69217 ? 263 LEU C CD1 1 
ATOM   6106 C  CD2 . LEU C 1 265 ? 23.68368  27.57008  -36.77932 1.000 33.72629 ? 263 LEU C CD2 1 
ATOM   6107 N  N   . GLY C 1 266 ? 26.47826  23.36117  -39.07921 1.000 32.21483 ? 264 GLY C N   1 
ATOM   6108 C  CA  . GLY C 1 266 ? 27.66588  22.53614  -39.23705 1.000 35.95080 ? 264 GLY C CA  1 
ATOM   6109 C  C   . GLY C 1 266 ? 28.62801  23.17393  -40.22810 1.000 36.53099 ? 264 GLY C C   1 
ATOM   6110 O  O   . GLY C 1 266 ? 28.22074  23.70182  -41.26214 1.000 36.07106 ? 264 GLY C O   1 
ATOM   6111 N  N   . THR C 1 267 ? 29.92239  23.13290  -39.90017 1.000 36.81879 ? 265 THR C N   1 
ATOM   6112 C  CA  . THR C 1 267 ? 30.95915  23.74974  -40.72800 1.000 39.20928 ? 265 THR C CA  1 
ATOM   6113 C  C   . THR C 1 267 ? 31.89367  22.72692  -41.36834 1.000 46.19681 ? 265 THR C C   1 
ATOM   6114 O  O   . THR C 1 267 ? 33.02082  23.07454  -41.75349 1.000 42.07047 ? 265 THR C O   1 
ATOM   6115 C  CB  . THR C 1 267 ? 31.76812  24.74359  -39.89836 1.000 41.04946 ? 265 THR C CB  1 
ATOM   6116 O  OG1 . THR C 1 267 ? 32.45644  24.04951  -38.85235 1.000 40.40683 ? 265 THR C OG1 1 
ATOM   6117 C  CG2 . THR C 1 267 ? 30.86131  25.82057  -39.31492 1.000 39.77464 ? 265 THR C CG2 1 
ATOM   6118 N  N   . ARG C 1 268 ? 31.41955  21.48269  -41.52755 1.000 40.87911 ? 266 ARG C N   1 
ATOM   6119 C  CA  . ARG C 1 268 ? 32.22935  20.31439  -41.84885 1.000 45.02140 ? 266 ARG C CA  1 
ATOM   6120 C  C   . ARG C 1 268 ? 31.82193  19.60295  -43.12163 1.000 47.43907 ? 266 ARG C C   1 
ATOM   6121 O  O   . ARG C 1 268 ? 32.51781  18.65916  -43.53019 1.000 47.94855 ? 266 ARG C O   1 
ATOM   6122 C  CB  . ARG C 1 268 ? 32.10479  19.26294  -40.74012 1.000 45.67277 ? 266 ARG C CB  1 
ATOM   6123 C  CG  . ARG C 1 268 ? 32.75877  19.58878  -39.48829 1.000 43.30017 ? 266 ARG C CG  1 
ATOM   6124 C  CD  . ARG C 1 268 ? 33.38749  18.34812  -39.01608 1.000 44.07494 ? 266 ARG C CD  1 
ATOM   6125 N  NE  . ARG C 1 268 ? 34.16586  18.65729  -37.83713 1.000 48.76525 ? 266 ARG C NE  1 
ATOM   6126 C  CZ  . ARG C 1 268 ? 35.42566  18.30324  -37.66790 1.000 45.51266 ? 266 ARG C CZ  1 
ATOM   6127 N  NH1 . ARG C 1 268 ? 36.06400  17.56560  -38.56674 1.000 43.21784 ? 266 ARG C NH1 1 
ATOM   6128 N  NH2 . ARG C 1 268 ? 36.06060  18.70879  -36.57467 1.000 44.04430 ? 266 ARG C NH2 1 
ATOM   6129 N  N   . HIS C 1 269 ? 30.66576  19.92757  -43.68855 1.000 43.71191 ? 267 HIS C N   1 
ATOM   6130 C  CA  . HIS C 1 269 ? 30.11574  19.05244  -44.70843 1.000 45.83533 ? 267 HIS C CA  1 
ATOM   6131 C  C   . HIS C 1 269 ? 30.98865  19.09156  -45.95683 1.000 48.19163 ? 267 HIS C C   1 
ATOM   6132 O  O   . HIS C 1 269 ? 31.45485  20.15627  -46.36939 1.000 48.78314 ? 267 HIS C O   1 
ATOM   6133 C  CB  . HIS C 1 269 ? 28.68112  19.43554  -45.05292 1.000 41.03759 ? 267 HIS C CB  1 
ATOM   6134 C  CG  . HIS C 1 269 ? 28.01340  18.43561  -45.93757 1.000 44.74020 ? 267 HIS C CG  1 
ATOM   6135 N  ND1 . HIS C 1 269 ? 27.37048  17.32167  -45.44574 1.000 43.21236 ? 267 HIS C ND1 1 
ATOM   6136 C  CD2 . HIS C 1 269 ? 27.95060  18.34334  -47.28764 1.000 47.71230 ? 267 HIS C CD2 1 
ATOM   6137 C  CE1 . HIS C 1 269 ? 26.91708  16.59829  -46.45513 1.000 48.22516 ? 267 HIS C CE1 1 
ATOM   6138 N  NE2 . HIS C 1 269 ? 27.24902  17.20075  -47.58361 1.000 49.25852 ? 267 HIS C NE2 1 
ATOM   6139 N  N   . ASP C 1 270 ? 31.22337  17.90851  -46.53312 1.000 49.00022 ? 268 ASP C N   1 
ATOM   6140 C  CA  . ASP C 1 270 ? 32.03906  17.71287  -47.73284 1.000 52.84044 ? 268 ASP C CA  1 
ATOM   6141 C  C   . ASP C 1 270 ? 33.51247  18.04211  -47.50966 1.000 55.20320 ? 268 ASP C C   1 
ATOM   6142 O  O   . ASP C 1 270 ? 34.25094  18.24284  -48.47923 1.000 53.92763 ? 268 ASP C O   1 
ATOM   6143 C  CB  . ASP C 1 270 ? 31.50942  18.52985  -48.91828 1.000 49.31822 ? 268 ASP C CB  1 
ATOM   6144 C  CG  . ASP C 1 270 ? 30.44967  17.78727  -49.69669 1.000 54.96084 ? 268 ASP C CG  1 
ATOM   6145 O  OD1 . ASP C 1 270 ? 30.55726  16.54551  -49.78611 1.000 55.56191 ? 268 ASP C OD1 1 
ATOM   6146 O  OD2 . ASP C 1 270 ? 29.51441  18.43864  -50.21896 1.000 57.74326 ? 268 ASP C OD2 1 
ATOM   6147 N  N   . THR C 1 271 ? 33.96812  18.10747  -46.25303 1.000 53.98535 ? 269 THR C N   1 
ATOM   6148 C  CA  . THR C 1 271 ? 35.37208  18.37665  -45.96022 1.000 53.78104 ? 269 THR C CA  1 
ATOM   6149 C  C   . THR C 1 271 ? 36.10751  17.26269  -45.22035 1.000 57.02514 ? 269 THR C C   1 
ATOM   6150 O  O   . THR C 1 271 ? 37.33135  17.35887  -45.07625 1.000 57.80736 ? 269 THR C O   1 
ATOM   6151 C  CB  . THR C 1 271 ? 35.52795  19.68206  -45.15436 1.000 52.39021 ? 269 THR C CB  1 
ATOM   6152 O  OG1 . THR C 1 271 ? 35.21651  19.43959  -43.76671 1.000 53.52654 ? 269 THR C OG1 1 
ATOM   6153 C  CG2 . THR C 1 271 ? 34.69796  20.83786  -45.75363 1.000 50.19582 ? 269 THR C CG2 1 
ATOM   6154 N  N   . ASP C 1 272 ? 35.42732  16.21685  -44.75647 1.000 53.79386 ? 270 ASP C N   1 
ATOM   6155 C  CA  . ASP C 1 272 ? 36.10220  15.14473  -44.04014 1.000 52.86534 ? 270 ASP C CA  1 
ATOM   6156 C  C   . ASP C 1 272 ? 36.21517  13.89559  -44.89923 1.000 53.95620 ? 270 ASP C C   1 
ATOM   6157 O  O   . ASP C 1 272 ? 35.54940  13.75376  -45.92839 1.000 56.00829 ? 270 ASP C O   1 
ATOM   6158 C  CB  . ASP C 1 272 ? 35.38151  14.78896  -42.73349 1.000 55.14395 ? 270 ASP C CB  1 
ATOM   6159 C  CG  . ASP C 1 272 ? 35.21233  15.97825  -41.80611 1.000 50.08932 ? 270 ASP C CG  1 
ATOM   6160 O  OD1 . ASP C 1 272 ? 36.23584  16.47899  -41.28213 1.000 50.37327 ? 270 ASP C OD1 1 
ATOM   6161 O  OD2 . ASP C 1 272 ? 34.04994  16.38403  -41.58278 1.000 50.09173 ? 270 ASP C OD2 1 
ATOM   6162 N  N   . ALA C 1 273 ? 37.04705  12.97538  -44.41231 1.000 53.65800 ? 271 ALA C N   1 
ATOM   6163 C  CA  . ALA C 1 273 ? 37.40174  11.74474  -45.10624 1.000 55.76141 ? 271 ALA C CA  1 
ATOM   6164 C  C   . ALA C 1 273 ? 38.04621  10.80424  -44.09465 1.000 56.03856 ? 271 ALA C C   1 
ATOM   6165 O  O   . ALA C 1 273 ? 38.40863  11.22294  -42.98882 1.000 54.77361 ? 271 ALA C O   1 
ATOM   6166 C  CB  . ALA C 1 273 ? 38.34850  12.02839  -46.28434 1.000 55.64073 ? 271 ALA C CB  1 
ATOM   6167 N  N   . PRO C 1 274 ? 38.16652  9.50891   -44.42222 1.000 59.53652 ? 272 PRO C N   1 
ATOM   6168 C  CA  . PRO C 1 274 ? 38.82648  8.61161   -43.46485 1.000 57.89331 ? 272 PRO C CA  1 
ATOM   6169 C  C   . PRO C 1 274 ? 40.32415  8.89350   -43.28926 1.000 57.82416 ? 272 PRO C C   1 
ATOM   6170 O  O   . PRO C 1 274 ? 40.85827  8.57046   -42.22233 1.000 56.74079 ? 272 PRO C O   1 
ATOM   6171 C  CB  . PRO C 1 274 ? 38.59730  7.22457   -44.07285 1.000 59.14961 ? 272 PRO C CB  1 
ATOM   6172 C  CG  . PRO C 1 274 ? 37.40613  7.40345   -44.98119 1.000 57.24158 ? 272 PRO C CG  1 
ATOM   6173 C  CD  . PRO C 1 274 ? 37.55018  8.77120   -45.53713 1.000 56.88928 ? 272 PRO C CD  1 
ATOM   6174 N  N   . MET D 1 3   ? -19.05811 3.22023   -39.68856 1.000 66.18838 ? 1   MET D N   1 
ATOM   6175 C  CA  . MET D 1 3   ? -19.82397 3.13043   -38.44375 1.000 62.81865 ? 1   MET D CA  1 
ATOM   6176 C  C   . MET D 1 3   ? -18.93369 2.69588   -37.26898 1.000 54.88997 ? 1   MET D C   1 
ATOM   6177 O  O   . MET D 1 3   ? -18.04929 1.86909   -37.42944 1.000 53.66897 ? 1   MET D O   1 
ATOM   6178 C  CB  . MET D 1 3   ? -21.01875 2.19939   -38.65150 1.000 61.41918 ? 1   MET D CB  1 
ATOM   6179 C  CG  . MET D 1 3   ? -21.41590 1.31126   -37.50151 1.000 61.11537 ? 1   MET D CG  1 
ATOM   6180 S  SD  . MET D 1 3   ? -22.98765 0.57314   -37.99288 1.000 79.65297 ? 1   MET D SD  1 
ATOM   6181 C  CE  . MET D 1 3   ? -22.88873 -1.08358  -37.32686 1.000 58.92111 ? 1   MET D CE  1 
ATOM   6182 N  N   . LYS D 1 4   ? -19.17925 3.25641   -36.08746 1.000 54.71108 ? 2   LYS D N   1 
ATOM   6183 C  CA  . LYS D 1 4   ? -18.10843 3.45253   -35.11403 1.000 52.63845 ? 2   LYS D CA  1 
ATOM   6184 C  C   . LYS D 1 4   ? -18.62836 4.18871   -33.87962 1.000 50.71923 ? 2   LYS D C   1 
ATOM   6185 O  O   . LYS D 1 4   ? -19.76276 4.67364   -33.85062 1.000 51.50863 ? 2   LYS D O   1 
ATOM   6186 C  CB  . LYS D 1 4   ? -16.97094 4.20159   -35.81492 1.000 51.30012 ? 2   LYS D CB  1 
ATOM   6187 C  CG  . LYS D 1 4   ? -17.15950 5.69988   -35.82251 1.000 53.88809 ? 2   LYS D CG  1 
ATOM   6188 C  CD  . LYS D 1 4   ? -16.43676 6.30522   -37.01767 1.000 55.37835 ? 2   LYS D CD  1 
ATOM   6189 C  CE  . LYS D 1 4   ? -16.00472 7.73721   -36.75124 1.000 56.24329 ? 2   LYS D CE  1 
ATOM   6190 N  NZ  . LYS D 1 4   ? -16.90029 8.39630   -35.74701 1.000 58.93397 ? 2   LYS D NZ  1 
ATOM   6191 N  N   . ARG D 1 5   ? -17.78990 4.22761   -32.84387 1.000 46.28806 ? 3   ARG D N   1 
ATOM   6192 C  CA  . ARG D 1 5   ? -18.04732 4.94479   -31.60116 1.000 44.33146 ? 3   ARG D CA  1 
ATOM   6193 C  C   . ARG D 1 5   ? -16.96633 5.99804   -31.38933 1.000 44.23771 ? 3   ARG D C   1 
ATOM   6194 O  O   . ARG D 1 5   ? -15.91691 5.97550   -32.02719 1.000 42.54066 ? 3   ARG D O   1 
ATOM   6195 C  CB  . ARG D 1 5   ? -18.07551 3.99273   -30.39851 1.000 42.96961 ? 3   ARG D CB  1 
ATOM   6196 C  CG  . ARG D 1 5   ? -19.33769 3.15462   -30.27246 1.000 43.40693 ? 3   ARG D CG  1 
ATOM   6197 C  CD  . ARG D 1 5   ? -19.23311 2.19694   -29.09655 1.000 41.21490 ? 3   ARG D CD  1 
ATOM   6198 N  NE  . ARG D 1 5   ? -20.22025 1.12503   -29.17785 1.000 43.71534 ? 3   ARG D NE  1 
ATOM   6199 C  CZ  . ARG D 1 5   ? -21.39345 1.15636   -28.55811 1.000 46.14669 ? 3   ARG D CZ  1 
ATOM   6200 N  NH1 . ARG D 1 5   ? -21.75842 2.19902   -27.82375 1.000 44.87814 ? 3   ARG D NH1 1 
ATOM   6201 N  NH2 . ARG D 1 5   ? -22.23039 0.13014   -28.69471 1.000 45.32588 ? 3   ARG D NH2 1 
ATOM   6202 N  N   . SER D 1 6   ? -17.22601 6.92022   -30.46640 1.000 43.84108 ? 4   SER D N   1 
ATOM   6203 C  CA  . SER D 1 6   ? -16.25603 7.93457   -30.08069 1.000 43.17581 ? 4   SER D CA  1 
ATOM   6204 C  C   . SER D 1 6   ? -16.26462 8.08089   -28.57022 1.000 43.36702 ? 4   SER D C   1 
ATOM   6205 O  O   . SER D 1 6   ? -17.32940 8.08588   -27.94598 1.000 41.24019 ? 4   SER D O   1 
ATOM   6206 C  CB  . SER D 1 6   ? -16.55764 9.29401   -30.72498 1.000 43.20411 ? 4   SER D CB  1 
ATOM   6207 O  OG  . SER D 1 6   ? -15.66339 10.27427  -30.24052 1.000 43.36703 ? 4   SER D OG  1 
ATOM   6208 N  N   . LEU D 1 7   ? -15.07670 8.20026   -27.98312 1.000 40.12032 ? 5   LEU D N   1 
ATOM   6209 C  CA  . LEU D 1 7   ? -15.01968 8.47500   -26.55816 1.000 38.54045 ? 5   LEU D CA  1 
ATOM   6210 C  C   . LEU D 1 7   ? -15.25392 9.93854   -26.24317 1.000 42.34207 ? 5   LEU D C   1 
ATOM   6211 O  O   . LEU D 1 7   ? -15.44359 10.27569  -25.07579 1.000 43.99073 ? 5   LEU D O   1 
ATOM   6212 C  CB  . LEU D 1 7   ? -13.67222 8.05403   -25.98591 1.000 39.54944 ? 5   LEU D CB  1 
ATOM   6213 C  CG  . LEU D 1 7   ? -13.54013 6.55289   -25.72479 1.000 41.66799 ? 5   LEU D CG  1 
ATOM   6214 C  CD1 . LEU D 1 7   ? -12.10217 6.25443   -25.39924 1.000 37.77082 ? 5   LEU D CD1 1 
ATOM   6215 C  CD2 . LEU D 1 7   ? -14.47342 6.06816   -24.60201 1.000 39.71879 ? 5   LEU D CD2 1 
ATOM   6216 N  N   . ASN D 1 8   ? -15.21678 10.81370  -27.24253 1.000 39.47662 ? 6   ASN D N   1 
ATOM   6217 C  CA  . ASN D 1 8   ? -15.48497 12.24001  -27.05515 1.000 42.60202 ? 6   ASN D CA  1 
ATOM   6218 C  C   . ASN D 1 8   ? -16.35940 12.69577  -28.21302 1.000 44.41656 ? 6   ASN D C   1 
ATOM   6219 O  O   . ASN D 1 8   ? -15.91293 13.41560  -29.11142 1.000 44.20777 ? 6   ASN D O   1 
ATOM   6220 C  CB  . ASN D 1 8   ? -14.17966 13.03484  -26.94497 1.000 42.04981 ? 6   ASN D CB  1 
ATOM   6221 C  CG  . ASN D 1 8   ? -13.24381 12.82556  -28.13550 1.000 40.87365 ? 6   ASN D CG  1 
ATOM   6222 O  OD1 . ASN D 1 8   ? -13.19149 11.74214  -28.74106 1.000 42.50709 ? 6   ASN D OD1 1 
ATOM   6223 N  ND2 . ASN D 1 8   ? -12.50237 13.85955  -28.47124 1.000 38.77096 ? 6   ASN D ND2 1 
ATOM   6224 N  N   . PRO D 1 9   ? -17.63080 12.27271  -28.22176 1.000 46.73618 ? 7   PRO D N   1 
ATOM   6225 C  CA  . PRO D 1 9   ? -18.45288 12.42124  -29.43517 1.000 48.16568 ? 7   PRO D CA  1 
ATOM   6226 C  C   . PRO D 1 9   ? -18.82837 13.85703  -29.75078 1.000 58.36670 ? 7   PRO D C   1 
ATOM   6227 O  O   . PRO D 1 9   ? -19.04945 14.18988  -30.92323 1.000 63.96081 ? 7   PRO D O   1 
ATOM   6228 C  CB  . PRO D 1 9   ? -19.69943 11.58575  -29.11165 1.000 54.16467 ? 7   PRO D CB  1 
ATOM   6229 C  CG  . PRO D 1 9   ? -19.79710 11.61980  -27.61572 1.000 50.19423 ? 7   PRO D CG  1 
ATOM   6230 C  CD  . PRO D 1 9   ? -18.37105 11.63220  -27.11870 1.000 47.52374 ? 7   PRO D CD  1 
ATOM   6231 N  N   . ASP D 1 10  ? -18.91130 14.72299  -28.74816 1.000 56.32255 ? 8   ASP D N   1 
ATOM   6232 C  CA  . ASP D 1 10  ? -19.36221 16.07982  -29.00872 1.000 61.39610 ? 8   ASP D CA  1 
ATOM   6233 C  C   . ASP D 1 10  ? -18.28062 16.93668  -29.64310 1.000 62.16354 ? 8   ASP D C   1 
ATOM   6234 O  O   . ASP D 1 10  ? -18.61233 17.94015  -30.28112 1.000 63.68557 ? 8   ASP D O   1 
ATOM   6235 C  CB  . ASP D 1 10  ? -19.85856 16.71485  -27.71043 1.000 62.10557 ? 8   ASP D CB  1 
ATOM   6236 C  CG  . ASP D 1 10  ? -21.17440 16.11520  -27.25000 1.000 67.42467 ? 8   ASP D CG  1 
ATOM   6237 O  OD1 . ASP D 1 10  ? -21.96531 15.68779  -28.12049 1.000 64.73335 ? 8   ASP D OD1 1 
ATOM   6238 O  OD2 . ASP D 1 10  ? -21.41341 16.06330  -26.02608 1.000 70.00352 ? 8   ASP D OD2 1 
ATOM   6239 N  N   . GLU D 1 11  ? -17.00345 16.53432  -29.50598 1.000 61.16710 ? 9   GLU D N   1 
ATOM   6240 C  CA  . GLU D 1 11  ? -15.82027 17.24358  -29.97900 1.000 55.93228 ? 9   GLU D CA  1 
ATOM   6241 C  C   . GLU D 1 11  ? -16.10147 17.95632  -31.29060 1.000 59.75321 ? 9   GLU D C   1 
ATOM   6242 O  O   . GLU D 1 11  ? -16.53706 17.31494  -32.25494 1.000 64.62757 ? 9   GLU D O   1 
ATOM   6243 C  CB  . GLU D 1 11  ? -14.64745 16.27978  -30.17628 1.000 54.93397 ? 9   GLU D CB  1 
ATOM   6244 C  CG  . GLU D 1 11  ? -13.35017 16.99928  -30.44334 1.000 52.02884 ? 9   GLU D CG  1 
ATOM   6245 C  CD  . GLU D 1 11  ? -12.81818 17.61197  -29.17859 1.000 52.76173 ? 9   GLU D CD  1 
ATOM   6246 O  OE1 . GLU D 1 11  ? -12.98519 16.97263  -28.10846 1.000 56.24687 ? 9   GLU D OE1 1 
ATOM   6247 O  OE2 . GLU D 1 11  ? -12.30980 18.74670  -29.23152 1.000 50.23950 ? 9   GLU D OE2 1 
ATOM   6248 N  N   . PRO D 1 12  ? -15.90829 19.27735  -31.35926 1.000 63.72005 ? 10  PRO D N   1 
ATOM   6249 C  CA  . PRO D 1 12  ? -16.03124 19.96057  -32.65111 1.000 62.22849 ? 10  PRO D CA  1 
ATOM   6250 C  C   . PRO D 1 12  ? -15.11710 19.33667  -33.68350 1.000 61.31190 ? 10  PRO D C   1 
ATOM   6251 O  O   . PRO D 1 12  ? -15.57557 18.59097  -34.55742 1.000 64.05277 ? 10  PRO D O   1 
ATOM   6252 C  CB  . PRO D 1 12  ? -15.63175 21.41031  -32.33095 1.000 63.01231 ? 10  PRO D CB  1 
ATOM   6253 C  CG  . PRO D 1 12  ? -14.93908 21.35394  -30.99220 1.000 61.60483 ? 10  PRO D CG  1 
ATOM   6254 C  CD  . PRO D 1 12  ? -15.60292 20.22066  -30.26633 1.000 59.62820 ? 10  PRO D CD  1 
ATOM   6255 N  N   . ASN D 1 13  ? -13.81631 19.60940  -33.55409 1.000 61.17926 ? 11  ASN D N   1 
ATOM   6256 C  CA  . ASN D 1 13  ? -12.80280 19.16343  -34.50556 1.000 55.12505 ? 11  ASN D CA  1 
ATOM   6257 C  C   . ASN D 1 13  ? -12.80106 17.64427  -34.65260 1.000 53.69970 ? 11  ASN D C   1 
ATOM   6258 O  O   . ASN D 1 13  ? -12.39799 16.92405  -33.73281 1.000 54.03134 ? 11  ASN D O   1 
ATOM   6259 C  CB  . ASN D 1 13  ? -11.42976 19.68088  -34.06243 1.000 50.89063 ? 11  ASN D CB  1 
ATOM   6260 C  CG  . ASN D 1 13  ? -10.37469 19.54876  -35.14101 1.000 51.91323 ? 11  ASN D CG  1 
ATOM   6261 O  OD1 . ASN D 1 13  ? -10.56069 18.83190  -36.12744 1.000 50.68050 ? 11  ASN D OD1 1 
ATOM   6262 N  ND2 . ASN D 1 13  ? -9.25285  20.25370  -34.96349 1.000 51.06272 ? 11  ASN D ND2 1 
ATOM   6263 N  N   . ALA D 1 14  ? -13.24118 17.14676  -35.81354 1.000 54.64599 ? 12  ALA D N   1 
ATOM   6264 C  CA  . ALA D 1 14  ? -13.32362 15.70536  -36.02830 1.000 48.94634 ? 12  ALA D CA  1 
ATOM   6265 C  C   . ALA D 1 14  ? -11.96666 15.02262  -35.92979 1.000 49.27810 ? 12  ALA D C   1 
ATOM   6266 O  O   . ALA D 1 14  ? -11.91335 13.82350  -35.63441 1.000 45.91136 ? 12  ALA D O   1 
ATOM   6267 C  CB  . ALA D 1 14  ? -13.94853 15.40277  -37.39075 1.000 48.95633 ? 12  ALA D CB  1 
ATOM   6268 N  N   . LEU D 1 15  ? -10.87442 15.75762  -36.16218 1.000 44.93692 ? 13  LEU D N   1 
ATOM   6269 C  CA  . LEU D 1 15  ? -9.52852  15.20824  -36.04545 1.000 47.09265 ? 13  LEU D CA  1 
ATOM   6270 C  C   . LEU D 1 15  ? -9.11156  14.95082  -34.60403 1.000 41.97436 ? 13  LEU D C   1 
ATOM   6271 O  O   . LEU D 1 15  ? -8.11910  14.24662  -34.38047 1.000 45.10050 ? 13  LEU D O   1 
ATOM   6272 C  CB  . LEU D 1 15  ? -8.50643  16.13688  -36.72128 1.000 46.88529 ? 13  LEU D CB  1 
ATOM   6273 C  CG  . LEU D 1 15  ? -8.61091  16.36697  -38.23820 1.000 49.92115 ? 13  LEU D CG  1 
ATOM   6274 C  CD1 . LEU D 1 15  ? -7.48919  17.29829  -38.73310 1.000 49.51649 ? 13  LEU D CD1 1 
ATOM   6275 C  CD2 . LEU D 1 15  ? -8.57376  15.04364  -38.99197 1.000 48.43607 ? 13  LEU D CD2 1 
ATOM   6276 N  N   . LEU D 1 16  ? -9.83945  15.47646  -33.63336 1.000 40.20411 ? 14  LEU D N   1 
ATOM   6277 C  CA  . LEU D 1 16  ? -9.56010  15.23757  -32.22782 1.000 38.93297 ? 14  LEU D CA  1 
ATOM   6278 C  C   . LEU D 1 16  ? -10.41707 14.12073  -31.65655 1.000 38.79008 ? 14  LEU D C   1 
ATOM   6279 O  O   . LEU D 1 16  ? -10.33303 13.84605  -30.46127 1.000 37.75649 ? 14  LEU D O   1 
ATOM   6280 C  CB  . LEU D 1 16  ? -9.77907  16.52561  -31.40936 1.000 39.52420 ? 14  LEU D CB  1 
ATOM   6281 C  CG  . LEU D 1 16  ? -8.89624  17.74945  -31.69779 1.000 47.04487 ? 14  LEU D CG  1 
ATOM   6282 C  CD1 . LEU D 1 16  ? -8.71274  18.61951  -30.44321 1.000 42.94800 ? 14  LEU D CD1 1 
ATOM   6283 C  CD2 . LEU D 1 16  ? -7.55277  17.31334  -32.22437 1.000 43.84962 ? 14  LEU D CD2 1 
ATOM   6284 N  N   . SER D 1 17  ? -11.25071 13.49562  -32.47742 1.000 38.99957 ? 15  SER D N   1 
ATOM   6285 C  CA  . SER D 1 17  ? -12.15677 12.46132  -32.01370 1.000 41.96555 ? 15  SER D CA  1 
ATOM   6286 C  C   . SER D 1 17  ? -11.41024 11.14061  -31.85926 1.000 38.49380 ? 15  SER D C   1 
ATOM   6287 O  O   . SER D 1 17  ? -10.70227 10.71485  -32.77364 1.000 37.64356 ? 15  SER D O   1 
ATOM   6288 C  CB  . SER D 1 17  ? -13.30502 12.28587  -33.00443 1.000 44.02071 ? 15  SER D CB  1 
ATOM   6289 O  OG  . SER D 1 17  ? -14.14621 11.21358  -32.60575 1.000 46.14014 ? 15  SER D OG  1 
ATOM   6290 N  N   . TYR D 1 18  ? -11.56736 10.49763  -30.71034 1.000 37.12057 ? 16  TYR D N   1 
ATOM   6291 C  CA  . TYR D 1 18  ? -11.05859 9.13234   -30.53308 1.000 35.13643 ? 16  TYR D CA  1 
ATOM   6292 C  C   . TYR D 1 18  ? -12.11888 8.15249   -31.01140 1.000 37.64368 ? 16  TYR D C   1 
ATOM   6293 O  O   . TYR D 1 18  ? -13.01016 7.75737   -30.25863 1.000 40.71877 ? 16  TYR D O   1 
ATOM   6294 C  CB  . TYR D 1 18  ? -10.69033 8.86685   -29.08551 1.000 33.94419 ? 16  TYR D CB  1 
ATOM   6295 C  CG  . TYR D 1 18  ? -9.71060  7.70506   -28.92150 1.000 36.06819 ? 16  TYR D CG  1 
ATOM   6296 C  CD1 . TYR D 1 18  ? -10.14053 6.40635   -28.77511 1.000 39.47420 ? 16  TYR D CD1 1 
ATOM   6297 C  CD2 . TYR D 1 18  ? -8.35001  7.94874   -28.90606 1.000 38.87658 ? 16  TYR D CD2 1 
ATOM   6298 C  CE1 . TYR D 1 18  ? -9.20782  5.36403   -28.62285 1.000 41.85003 ? 16  TYR D CE1 1 
ATOM   6299 C  CE2 . TYR D 1 18  ? -7.44759  6.96929   -28.74769 1.000 36.66234 ? 16  TYR D CE2 1 
ATOM   6300 C  CZ  . TYR D 1 18  ? -7.84590  5.68843   -28.61576 1.000 34.61204 ? 16  TYR D CZ  1 
ATOM   6301 O  OH  . TYR D 1 18  ? -6.86359  4.74319   -28.46002 1.000 39.44862 ? 16  TYR D OH  1 
ATOM   6302 N  N   . ASP D 1 19  ? -11.99500 7.72319   -32.26569 1.000 35.61865 ? 17  ASP D N   1 
ATOM   6303 C  CA  . ASP D 1 19  ? -12.90991 6.75829   -32.85954 1.000 36.59152 ? 17  ASP D CA  1 
ATOM   6304 C  C   . ASP D 1 19  ? -12.48127 5.32521   -32.55560 1.000 39.03276 ? 17  ASP D C   1 
ATOM   6305 O  O   . ASP D 1 19  ? -11.29981 4.96830   -32.65497 1.000 38.04866 ? 17  ASP D O   1 
ATOM   6306 C  CB  . ASP D 1 19  ? -12.99041 6.98686   -34.36965 1.000 42.49212 ? 17  ASP D CB  1 
ATOM   6307 C  CG  . ASP D 1 19  ? -13.53526 8.39010   -34.70876 1.000 45.27658 ? 17  ASP D CG  1 
ATOM   6308 O  OD1 . ASP D 1 19  ? -14.14558 9.02339   -33.80924 1.000 45.14062 ? 17  ASP D OD1 1 
ATOM   6309 O  OD2 . ASP D 1 19  ? -13.32800 8.86977   -35.84402 1.000 49.43897 ? 17  ASP D OD2 1 
ATOM   6310 N  N   . PHE D 1 20  ? -13.45650 4.49493   -32.19588 1.000 36.34827 ? 18  PHE D N   1 
ATOM   6311 C  CA  . PHE D 1 20  ? -13.18209 3.09918   -31.92448 1.000 37.40109 ? 18  PHE D CA  1 
ATOM   6312 C  C   . PHE D 1 20  ? -14.42809 2.28909   -32.25674 1.000 41.48903 ? 18  PHE D C   1 
ATOM   6313 O  O   . PHE D 1 20  ? -15.40571 2.81341   -32.80684 1.000 36.94527 ? 18  PHE D O   1 
ATOM   6314 C  CB  . PHE D 1 20  ? -12.71041 2.91529   -30.47732 1.000 38.00319 ? 18  PHE D CB  1 
ATOM   6315 C  CG  . PHE D 1 20  ? -13.80520 3.07001   -29.44693 1.000 39.58535 ? 18  PHE D CG  1 
ATOM   6316 C  CD1 . PHE D 1 20  ? -14.31051 4.34421   -29.12901 1.000 40.12695 ? 18  PHE D CD1 1 
ATOM   6317 C  CD2 . PHE D 1 20  ? -14.30512 1.96662   -28.77280 1.000 35.03606 ? 18  PHE D CD2 1 
ATOM   6318 C  CE1 . PHE D 1 20  ? -15.32125 4.49302   -28.17049 1.000 36.61120 ? 18  PHE D CE1 1 
ATOM   6319 C  CE2 . PHE D 1 20  ? -15.31023 2.09757   -27.82745 1.000 39.99818 ? 18  PHE D CE2 1 
ATOM   6320 C  CZ  . PHE D 1 20  ? -15.81576 3.36859   -27.51710 1.000 39.27673 ? 18  PHE D CZ  1 
ATOM   6321 N  N   . ASP D 1 21  ? -14.35305 0.98707   -31.95451 1.000 35.02960 ? 19  ASP D N   1 
ATOM   6322 C  CA  . ASP D 1 21  ? -15.42489 0.03029   -32.20622 1.000 39.04292 ? 19  ASP D CA  1 
ATOM   6323 C  C   . ASP D 1 21  ? -15.77965 0.00142   -33.68269 1.000 39.13810 ? 19  ASP D C   1 
ATOM   6324 O  O   . ASP D 1 21  ? -16.93889 0.15590   -34.06152 1.000 40.33151 ? 19  ASP D O   1 
ATOM   6325 C  CB  . ASP D 1 21  ? -16.67334 0.32171   -31.36163 1.000 37.42993 ? 19  ASP D CB  1 
ATOM   6326 C  CG  . ASP D 1 21  ? -17.61804 -0.88658  -31.28402 1.000 42.25426 ? 19  ASP D CG  1 
ATOM   6327 O  OD1 . ASP D 1 21  ? -17.10995 -2.02802  -31.26699 1.000 44.53168 ? 19  ASP D OD1 1 
ATOM   6328 O  OD2 . ASP D 1 21  ? -18.85569 -0.71677  -31.23012 1.000 45.02169 ? 19  ASP D OD2 1 
ATOM   6329 N  N   . ARG D 1 22  ? -14.77044 -0.18663  -34.52763 1.000 38.58137 ? 20  ARG D N   1 
ATOM   6330 C  CA  . ARG D 1 22  ? -15.03899 -0.20438  -35.95487 1.000 39.71294 ? 20  ARG D CA  1 
ATOM   6331 C  C   . ARG D 1 22  ? -15.34327 -1.59878  -36.47668 1.000 43.84036 ? 20  ARG D C   1 
ATOM   6332 O  O   . ARG D 1 22  ? -15.52931 -1.75930  -37.68784 1.000 46.30286 ? 20  ARG D O   1 
ATOM   6333 C  CB  . ARG D 1 22  ? -13.87700 0.41735   -36.73603 1.000 44.83962 ? 20  ARG D CB  1 
ATOM   6334 C  CG  . ARG D 1 22  ? -13.29763 1.66964   -36.06900 1.000 43.39011 ? 20  ARG D CG  1 
ATOM   6335 C  CD  . ARG D 1 22  ? -12.88809 2.73609   -37.09582 1.000 53.20110 ? 20  ARG D CD  1 
ATOM   6336 N  NE  . ARG D 1 22  ? -12.00966 2.24417   -38.14961 1.000 52.85312 ? 20  ARG D NE  1 
ATOM   6337 C  CZ  . ARG D 1 22  ? -11.83854 2.86171   -39.31175 1.000 56.62348 ? 20  ARG D CZ  1 
ATOM   6338 N  NH1 . ARG D 1 22  ? -12.49042 3.97946   -39.60399 1.000 59.12757 ? 20  ARG D NH1 1 
ATOM   6339 N  NH2 . ARG D 1 22  ? -11.01193 2.33535   -40.21172 1.000 57.84441 ? 20  ARG D NH2 1 
ATOM   6340 N  N   . GLY D 1 23  ? -15.42246 -2.59783  -35.59282 1.000 38.49773 ? 21  GLY D N   1 
ATOM   6341 C  CA  . GLY D 1 23  ? -15.74297 -3.95330  -35.98207 1.000 43.93194 ? 21  GLY D CA  1 
ATOM   6342 C  C   . GLY D 1 23  ? -14.63037 -4.70173  -36.68099 1.000 44.26911 ? 21  GLY D C   1 
ATOM   6343 O  O   . GLY D 1 23  ? -14.90308 -5.73494  -37.30537 1.000 41.93778 ? 21  GLY D O   1 
ATOM   6344 N  N   . SER D 1 24  ? -13.39200 -4.20994  -36.61396 1.000 37.67024 ? 22  SER D N   1 
ATOM   6345 C  CA  . SER D 1 24  ? -12.27202 -4.91127  -37.23119 1.000 39.58197 ? 22  SER D CA  1 
ATOM   6346 C  C   . SER D 1 24  ? -11.96233 -6.21172  -36.49446 1.000 36.08814 ? 22  SER D C   1 
ATOM   6347 O  O   . SER D 1 24  ? -12.29611 -6.39407  -35.31889 1.000 39.19656 ? 22  SER D O   1 
ATOM   6348 C  CB  . SER D 1 24  ? -11.02887 -4.01423  -37.24585 1.000 38.31464 ? 22  SER D CB  1 
ATOM   6349 O  OG  . SER D 1 24  ? -10.46121 -3.94354  -35.94745 1.000 38.87974 ? 22  SER D OG  1 
ATOM   6350 N  N   . ASN D 1 25  ? -11.30344 -7.12211  -37.20282 1.000 33.94932 ? 23  ASN D N   1 
ATOM   6351 C  CA  . ASN D 1 25  ? -10.92059 -8.39214  -36.59718 1.000 36.96524 ? 23  ASN D CA  1 
ATOM   6352 C  C   . ASN D 1 25  ? -9.89194  -8.20667  -35.49303 1.000 33.13183 ? 23  ASN D C   1 
ATOM   6353 O  O   . ASN D 1 25  ? -9.95233  -8.89232  -34.46301 1.000 33.17626 ? 23  ASN D O   1 
ATOM   6354 C  CB  . ASN D 1 25  ? -10.41694 -9.34599  -37.67384 1.000 37.85653 ? 23  ASN D CB  1 
ATOM   6355 C  CG  . ASN D 1 25  ? -11.55113 -10.01498 -38.38962 1.000 37.61331 ? 23  ASN D CG  1 
ATOM   6356 O  OD1 . ASN D 1 25  ? -12.55493 -10.28665 -37.78037 1.000 41.08798 ? 23  ASN D OD1 1 
ATOM   6357 N  ND2 . ASN D 1 25  ? -11.40710 -10.26566 -39.68136 1.000 42.47496 ? 23  ASN D ND2 1 
ATOM   6358 N  N   . TYR D 1 26  ? -8.94275  -7.29150  -35.68426 1.000 33.35167 ? 24  TYR D N   1 
ATOM   6359 C  CA  . TYR D 1 26  ? -8.05675  -6.91060  -34.59422 1.000 30.11866 ? 24  TYR D CA  1 
ATOM   6360 C  C   . TYR D 1 26  ? -8.85224  -6.58635  -33.34108 1.000 31.54611 ? 24  TYR D C   1 
ATOM   6361 O  O   . TYR D 1 26  ? -8.57556  -7.11946  -32.26477 1.000 32.19183 ? 24  TYR D O   1 
ATOM   6362 C  CB  . TYR D 1 26  ? -7.21599  -5.71313  -35.02234 1.000 34.45078 ? 24  TYR D CB  1 
ATOM   6363 C  CG  . TYR D 1 26  ? -6.31059  -5.11576  -33.95962 1.000 33.64645 ? 24  TYR D CG  1 
ATOM   6364 C  CD1 . TYR D 1 26  ? -5.00274  -5.56999  -33.80992 1.000 33.35558 ? 24  TYR D CD1 1 
ATOM   6365 C  CD2 . TYR D 1 26  ? -6.74749  -4.08342  -33.12996 1.000 33.55491 ? 24  TYR D CD2 1 
ATOM   6366 C  CE1 . TYR D 1 26  ? -4.15352  -5.01158  -32.86367 1.000 30.86219 ? 24  TYR D CE1 1 
ATOM   6367 C  CE2 . TYR D 1 26  ? -5.90269  -3.52032  -32.16799 1.000 29.76404 ? 24  TYR D CE2 1 
ATOM   6368 C  CZ  . TYR D 1 26  ? -4.59940  -3.99765  -32.04953 1.000 31.65387 ? 24  TYR D CZ  1 
ATOM   6369 O  OH  . TYR D 1 26  ? -3.72742  -3.46993  -31.11341 1.000 29.16708 ? 24  TYR D OH  1 
ATOM   6370 N  N   . GLU D 1 27  ? -9.84215  -5.68857  -33.46356 1.000 33.99117 ? 25  GLU D N   1 
ATOM   6371 C  CA  . GLU D 1 27  ? -10.67506 -5.32637  -32.31720 1.000 35.07105 ? 25  GLU D CA  1 
ATOM   6372 C  C   . GLU D 1 27  ? -11.45268 -6.52314  -31.78834 1.000 31.65645 ? 25  GLU D C   1 
ATOM   6373 O  O   . GLU D 1 27  ? -11.61875 -6.67020  -30.57075 1.000 31.08928 ? 25  GLU D O   1 
ATOM   6374 C  CB  . GLU D 1 27  ? -11.64234 -4.20308  -32.69803 1.000 33.82810 ? 25  GLU D CB  1 
ATOM   6375 C  CG  . GLU D 1 27  ? -10.94751 -2.86957  -32.99763 1.000 31.97388 ? 25  GLU D CG  1 
ATOM   6376 C  CD  . GLU D 1 27  ? -11.83785 -1.88620  -33.73656 1.000 37.75056 ? 25  GLU D CD  1 
ATOM   6377 O  OE1 . GLU D 1 27  ? -12.08192 -2.10826  -34.94146 1.000 37.20314 ? 25  GLU D OE1 1 
ATOM   6378 O  OE2 . GLU D 1 27  ? -12.26350 -0.87875  -33.12838 1.000 36.60858 ? 25  GLU D OE2 1 
ATOM   6379 N  N   . ASN D 1 28  ? -11.97736 -7.36098  -32.68728 1.000 32.96033 ? 26  ASN D N   1 
ATOM   6380 C  CA  . ASN D 1 28  ? -12.77303 -8.51216  -32.25762 1.000 34.08162 ? 26  ASN D CA  1 
ATOM   6381 C  C   . ASN D 1 28  ? -11.93850 -9.48661  -31.43062 1.000 36.87433 ? 26  ASN D C   1 
ATOM   6382 O  O   . ASN D 1 28  ? -12.37239 -9.94654  -30.36166 1.000 35.44300 ? 26  ASN D O   1 
ATOM   6383 C  CB  . ASN D 1 28  ? -13.35964 -9.24902  -33.46786 1.000 38.82898 ? 26  ASN D CB  1 
ATOM   6384 C  CG  . ASN D 1 28  ? -14.46315 -8.47043  -34.18115 1.000 41.64618 ? 26  ASN D CG  1 
ATOM   6385 O  OD1 . ASN D 1 28  ? -14.98506 -7.48135  -33.67308 1.000 43.33644 ? 26  ASN D OD1 1 
ATOM   6386 N  ND2 . ASN D 1 28  ? -14.80837 -8.92253  -35.38911 1.000 44.36511 ? 26  ASN D ND2 1 
ATOM   6387 N  N   . VAL D 1 29  ? -10.74221 -9.83071  -31.92617 1.000 33.17957 ? 27  VAL D N   1 
ATOM   6388 C  CA  . VAL D 1 29  ? -9.89269  -10.80200 -31.23414 1.000 33.99321 ? 27  VAL D CA  1 
ATOM   6389 C  C   . VAL D 1 29  ? -9.57215  -10.32381 -29.82115 1.000 33.52542 ? 27  VAL D C   1 
ATOM   6390 O  O   . VAL D 1 29  ? -9.53718  -11.12125 -28.87391 1.000 32.71061 ? 27  VAL D O   1 
ATOM   6391 C  CB  . VAL D 1 29  ? -8.61162  -11.08549 -32.05370 1.000 36.97396 ? 27  VAL D CB  1 
ATOM   6392 C  CG1 . VAL D 1 29  ? -7.52665  -11.77385 -31.19428 1.000 31.98736 ? 27  VAL D CG1 1 
ATOM   6393 C  CG2 . VAL D 1 29  ? -8.92666  -11.99962 -33.27537 1.000 37.82638 ? 27  VAL D CG2 1 
ATOM   6394 N  N   . LEU D 1 30  ? -9.33637  -9.01678  -29.65488 1.000 33.62936 ? 28  LEU D N   1 
ATOM   6395 C  CA  . LEU D 1 30  ? -8.84343  -8.48825  -28.38979 1.000 34.89268 ? 28  LEU D CA  1 
ATOM   6396 C  C   . LEU D 1 30  ? -9.94207  -8.12134  -27.40646 1.000 35.05177 ? 28  LEU D C   1 
ATOM   6397 O  O   . LEU D 1 30  ? -9.62520  -7.83317  -26.24727 1.000 34.20886 ? 28  LEU D O   1 
ATOM   6398 C  CB  . LEU D 1 30  ? -7.96361  -7.25379  -28.62711 1.000 30.67651 ? 28  LEU D CB  1 
ATOM   6399 C  CG  . LEU D 1 30  ? -6.75698  -7.59785  -29.51546 1.000 30.68649 ? 28  LEU D CG  1 
ATOM   6400 C  CD1 . LEU D 1 30  ? -6.02207  -6.34364  -29.94794 1.000 31.54254 ? 28  LEU D CD1 1 
ATOM   6401 C  CD2 . LEU D 1 30  ? -5.83896  -8.57034  -28.79454 1.000 30.25560 ? 28  LEU D CD2 1 
ATOM   6402 N  N   . HIS D 1 31  ? -11.21164 -8.13018  -27.83331 1.000 35.45224 ? 29  HIS D N   1 
ATOM   6403 C  CA  . HIS D 1 31  ? -12.31257 -7.61670  -27.01754 1.000 35.43128 ? 29  HIS D CA  1 
ATOM   6404 C  C   . HIS D 1 31  ? -12.03768 -6.14886  -26.64691 1.000 35.24629 ? 29  HIS D C   1 
ATOM   6405 O  O   . HIS D 1 31  ? -12.29615 -5.70666  -25.52846 1.000 34.60142 ? 29  HIS D O   1 
ATOM   6406 C  CB  . HIS D 1 31  ? -12.53297 -8.47428  -25.76282 1.000 34.18576 ? 29  HIS D CB  1 
ATOM   6407 C  CG  . HIS D 1 31  ? -12.90547 -9.91584  -26.03226 1.000 36.80674 ? 29  HIS D CG  1 
ATOM   6408 N  ND1 . HIS D 1 31  ? -13.71424 -10.64225 -25.18227 1.000 36.60308 ? 29  HIS D ND1 1 
ATOM   6409 C  CD2 . HIS D 1 31  ? -12.53977 -10.77499 -27.01929 1.000 34.78594 ? 29  HIS D CD2 1 
ATOM   6410 C  CE1 . HIS D 1 31  ? -13.85356 -11.87384 -25.64145 1.000 38.30517 ? 29  HIS D CE1 1 
ATOM   6411 N  NE2 . HIS D 1 31  ? -13.15206 -11.98163 -26.75774 1.000 40.52659 ? 29  HIS D NE2 1 
ATOM   6412 N  N   . LEU D 1 32  ? -11.48073 -5.38896  -27.59521 1.000 32.96472 ? 30  LEU D N   1 
ATOM   6413 C  CA  . LEU D 1 32  ? -10.97359 -4.05353  -27.27634 1.000 35.88771 ? 30  LEU D CA  1 
ATOM   6414 C  C   . LEU D 1 32  ? -12.10397 -3.09753  -26.90389 1.000 33.69872 ? 30  LEU D C   1 
ATOM   6415 O  O   . LEU D 1 32  ? -11.95189 -2.26326  -25.99800 1.000 31.39569 ? 30  LEU D O   1 
ATOM   6416 C  CB  . LEU D 1 32  ? -10.17046 -3.49199  -28.46003 1.000 31.87238 ? 30  LEU D CB  1 
ATOM   6417 C  CG  . LEU D 1 32  ? -9.40606  -2.17642  -28.21620 1.000 32.40014 ? 30  LEU D CG  1 
ATOM   6418 C  CD1 . LEU D 1 32  ? -8.69144  -2.16580  -26.86550 1.000 30.20633 ? 30  LEU D CD1 1 
ATOM   6419 C  CD2 . LEU D 1 32  ? -8.42786  -1.86437  -29.35534 1.000 31.96419 ? 30  LEU D CD2 1 
ATOM   6420 N  N   . THR D 1 33  ? -13.24262 -3.20706  -27.59127 1.000 33.20594 ? 31  THR D N   1 
ATOM   6421 C  CA  . THR D 1 33  ? -14.35328 -2.29537  -27.32440 1.000 35.30552 ? 31  THR D CA  1 
ATOM   6422 C  C   . THR D 1 33  ? -14.82437 -2.42170  -25.88201 1.000 35.32388 ? 31  THR D C   1 
ATOM   6423 O  O   . THR D 1 33  ? -15.09713 -1.40873  -25.22304 1.000 36.16858 ? 31  THR D O   1 
ATOM   6424 C  CB  . THR D 1 33  ? -15.48492 -2.55160  -28.32181 1.000 35.87770 ? 31  THR D CB  1 
ATOM   6425 O  OG1 . THR D 1 33  ? -15.01360 -2.27275  -29.65883 1.000 34.75038 ? 31  THR D OG1 1 
ATOM   6426 C  CG2 . THR D 1 33  ? -16.72135 -1.68244  -28.01694 1.000 35.63697 ? 31  THR D CG2 1 
ATOM   6427 N  N   . ASP D 1 34  ? -14.86130 -3.65017  -25.35009 1.000 34.08691 ? 32  ASP D N   1 
ATOM   6428 C  CA  . ASP D 1 34  ? -15.29043 -3.84226  -23.96430 1.000 37.52699 ? 32  ASP D CA  1 
ATOM   6429 C  C   . ASP D 1 34  ? -14.29837 -3.24014  -22.98390 1.000 34.96774 ? 32  ASP D C   1 
ATOM   6430 O  O   . ASP D 1 34  ? -14.70184 -2.65366  -21.97610 1.000 33.68322 ? 32  ASP D O   1 
ATOM   6431 C  CB  . ASP D 1 34  ? -15.49321 -5.33066  -23.65801 1.000 39.28678 ? 32  ASP D CB  1 
ATOM   6432 C  CG  . ASP D 1 34  ? -16.76195 -5.87398  -24.25666 1.000 41.63493 ? 32  ASP D CG  1 
ATOM   6433 O  OD1 . ASP D 1 34  ? -17.64699 -5.06495  -24.61541 1.000 42.51070 ? 32  ASP D OD1 1 
ATOM   6434 O  OD2 . ASP D 1 34  ? -16.87339 -7.10391  -24.37660 1.000 48.12698 ? 32  ASP D OD2 1 
ATOM   6435 N  N   . ALA D 1 35  ? -12.99591 -3.39241  -23.24743 1.000 36.17430 ? 33  ALA D N   1 
ATOM   6436 C  CA  . ALA D 1 35  ? -11.97981 -2.79209  -22.37752 1.000 35.43124 ? 33  ALA D CA  1 
ATOM   6437 C  C   . ALA D 1 35  ? -12.03458 -1.26170  -22.41426 1.000 36.02202 ? 33  ALA D C   1 
ATOM   6438 O  O   . ALA D 1 35  ? -11.97138 -0.58833  -21.36981 1.000 31.22590 ? 33  ALA D O   1 
ATOM   6439 C  CB  . ALA D 1 35  ? -10.59729 -3.30631  -22.78662 1.000 36.24315 ? 33  ALA D CB  1 
ATOM   6440 N  N   . LEU D 1 36  ? -12.13490 -0.68788  -23.61426 1.000 33.86603 ? 34  LEU D N   1 
ATOM   6441 C  CA  . LEU D 1 36  ? -12.27445 0.75651   -23.72239 1.000 34.96750 ? 34  LEU D CA  1 
ATOM   6442 C  C   . LEU D 1 36  ? -13.57037 1.22670   -23.06679 1.000 34.76960 ? 34  LEU D C   1 
ATOM   6443 O  O   . LEU D 1 36  ? -13.63029 2.34340   -22.52739 1.000 32.75799 ? 34  LEU D O   1 
ATOM   6444 C  CB  . LEU D 1 36  ? -12.22204 1.16477   -25.19818 1.000 35.44756 ? 34  LEU D CB  1 
ATOM   6445 C  CG  . LEU D 1 36  ? -10.85090 0.99928   -25.88451 1.000 32.36824 ? 34  LEU D CG  1 
ATOM   6446 C  CD1 . LEU D 1 36  ? -10.89542 1.37855   -27.38705 1.000 30.75098 ? 34  LEU D CD1 1 
ATOM   6447 C  CD2 . LEU D 1 36  ? -9.76721  1.78271   -25.15939 1.000 33.55542 ? 34  LEU D CD2 1 
ATOM   6448 N  N   . GLY D 1 37  ? -14.60443 0.37287   -23.08303 1.000 34.37707 ? 35  GLY D N   1 
ATOM   6449 C  CA  . GLY D 1 37  ? -15.87306 0.67972   -22.43447 1.000 33.36565 ? 35  GLY D CA  1 
ATOM   6450 C  C   . GLY D 1 37  ? -15.77502 0.86279   -20.93256 1.000 35.36881 ? 35  GLY D C   1 
ATOM   6451 O  O   . GLY D 1 37  ? -16.71568 1.37271   -20.31224 1.000 36.69361 ? 35  GLY D O   1 
ATOM   6452 N  N   . ALA D 1 38  ? -14.66934 0.45057   -20.32217 1.000 34.87833 ? 36  ALA D N   1 
ATOM   6453 C  CA  . ALA D 1 38  ? -14.51249 0.63500   -18.88796 1.000 35.20144 ? 36  ALA D CA  1 
ATOM   6454 C  C   . ALA D 1 38  ? -13.95706 2.00478   -18.50979 1.000 33.90718 ? 36  ALA D C   1 
ATOM   6455 O  O   . ALA D 1 38  ? -13.93446 2.34146   -17.32418 1.000 34.07225 ? 36  ALA D O   1 
ATOM   6456 C  CB  . ALA D 1 38  ? -13.61917 -0.47003  -18.30774 1.000 33.56636 ? 36  ALA D CB  1 
ATOM   6457 N  N   . LEU D 1 39  ? -13.51218 2.80867   -19.47009 1.000 32.93835 ? 37  LEU D N   1 
ATOM   6458 C  CA  . LEU D 1 39  ? -12.95993 4.11111   -19.13065 1.000 36.91014 ? 37  LEU D CA  1 
ATOM   6459 C  C   . LEU D 1 39  ? -14.08035 5.03899   -18.66180 1.000 37.04620 ? 37  LEU D C   1 
ATOM   6460 O  O   . LEU D 1 39  ? -15.18143 5.01112   -19.21876 1.000 34.48224 ? 37  LEU D O   1 
ATOM   6461 C  CB  . LEU D 1 39  ? -12.23676 4.70964   -20.34133 1.000 33.49112 ? 37  LEU D CB  1 
ATOM   6462 C  CG  . LEU D 1 39  ? -11.04950 3.89439   -20.87140 1.000 38.86953 ? 37  LEU D CG  1 
ATOM   6463 C  CD1 . LEU D 1 39  ? -10.49462 4.49964   -22.17501 1.000 38.36653 ? 37  LEU D CD1 1 
ATOM   6464 C  CD2 . LEU D 1 39  ? -9.97126  3.77263   -19.79732 1.000 37.02466 ? 37  LEU D CD2 1 
ATOM   6465 N  N   . VAL D 1 40  ? -13.81704 5.83062   -17.61527 1.000 36.39276 ? 38  VAL D N   1 
ATOM   6466 C  CA  . VAL D 1 40  ? -14.80515 6.82108   -17.15787 1.000 39.05996 ? 38  VAL D CA  1 
ATOM   6467 C  C   . VAL D 1 40  ? -15.22204 7.69848   -18.32757 1.000 40.45820 ? 38  VAL D C   1 
ATOM   6468 O  O   . VAL D 1 40  ? -14.36293 8.29596   -18.98265 1.000 38.85460 ? 38  VAL D O   1 
ATOM   6469 C  CB  . VAL D 1 40  ? -14.29754 7.72102   -16.01185 1.000 42.45737 ? 38  VAL D CB  1 
ATOM   6470 C  CG1 . VAL D 1 40  ? -15.42139 8.64427   -15.54850 1.000 42.12440 ? 38  VAL D CG1 1 
ATOM   6471 C  CG2 . VAL D 1 40  ? -13.90056 6.90403   -14.80709 1.000 43.89295 ? 38  VAL D CG2 1 
ATOM   6472 N  N   . PRO D 1 41  ? -16.51851 7.81382   -18.60672 1.000 42.50107 ? 39  PRO D N   1 
ATOM   6473 C  CA  . PRO D 1 41  ? -16.96175 8.63211   -19.74024 1.000 41.02949 ? 39  PRO D CA  1 
ATOM   6474 C  C   . PRO D 1 41  ? -16.56219 10.08678  -19.56708 1.000 42.92012 ? 39  PRO D C   1 
ATOM   6475 O  O   . PRO D 1 41  ? -16.55040 10.62922  -18.45615 1.000 40.68613 ? 39  PRO D O   1 
ATOM   6476 C  CB  . PRO D 1 41  ? -18.48288 8.45562   -19.72753 1.000 45.99906 ? 39  PRO D CB  1 
ATOM   6477 C  CG  . PRO D 1 41  ? -18.67750 7.10496   -19.04301 1.000 43.31098 ? 39  PRO D CG  1 
ATOM   6478 C  CD  . PRO D 1 41  ? -17.63399 7.09461   -17.97254 1.000 40.91350 ? 39  PRO D CD  1 
ATOM   6479 N  N   . GLU D 1 42  ? -16.22706 10.72014  -20.68895 1.000 39.08725 ? 40  GLU D N   1 
ATOM   6480 C  CA  . GLU D 1 42  ? -15.72755 12.08569  -20.61235 1.000 43.48714 ? 40  GLU D CA  1 
ATOM   6481 C  C   . GLU D 1 42  ? -16.79924 13.02407  -20.05483 1.000 45.81040 ? 40  GLU D C   1 
ATOM   6482 O  O   . GLU D 1 42  ? -16.49146 13.93511  -19.27778 1.000 42.20019 ? 40  GLU D O   1 
ATOM   6483 C  CB  . GLU D 1 42  ? -15.24129 12.54208  -21.99066 1.000 44.21884 ? 40  GLU D CB  1 
ATOM   6484 C  CG  . GLU D 1 42  ? -13.71103 12.39424  -22.16969 1.000 42.60316 ? 40  GLU D CG  1 
ATOM   6485 C  CD  . GLU D 1 42  ? -13.20677 12.95911  -23.49218 1.000 43.87251 ? 40  GLU D CD  1 
ATOM   6486 O  OE1 . GLU D 1 42  ? -13.41202 14.16158  -23.74109 1.000 44.41240 ? 40  GLU D OE1 1 
ATOM   6487 O  OE2 . GLU D 1 42  ? -12.60231 12.21842  -24.28395 1.000 46.48041 ? 40  GLU D OE2 1 
ATOM   6488 N  N   . SER D 1 43  ? -18.07214 12.76869  -20.38168 1.000 43.82448 ? 41  SER D N   1 
ATOM   6489 C  CA  . SER D 1 43  ? -19.16862 13.55886  -19.81869 1.000 45.64867 ? 41  SER D CA  1 
ATOM   6490 C  C   . SER D 1 43  ? -19.24935 13.45988  -18.30474 1.000 48.05845 ? 41  SER D C   1 
ATOM   6491 O  O   . SER D 1 43  ? -19.95937 14.25090  -17.68500 1.000 48.06693 ? 41  SER D O   1 
ATOM   6492 C  CB  . SER D 1 43  ? -20.50721 13.10938  -20.39570 1.000 43.65088 ? 41  SER D CB  1 
ATOM   6493 O  OG  . SER D 1 43  ? -20.79868 11.78385  -19.97955 1.000 48.82528 ? 41  SER D OG  1 
ATOM   6494 N  N   . GLU D 1 44  ? -18.55343 12.50756  -17.69346 1.000 44.58140 ? 42  GLU D N   1 
ATOM   6495 C  CA  . GLU D 1 44  ? -18.67168 12.27837  -16.26587 1.000 43.96637 ? 42  GLU D CA  1 
ATOM   6496 C  C   . GLU D 1 44  ? -17.39656 12.57599  -15.49696 1.000 43.91900 ? 42  GLU D C   1 
ATOM   6497 O  O   . GLU D 1 44  ? -17.41011 12.50158  -14.26851 1.000 45.06153 ? 42  GLU D O   1 
ATOM   6498 C  CB  . GLU D 1 44  ? -19.09269 10.81981  -15.99451 1.000 45.34299 ? 42  GLU D CB  1 
ATOM   6499 C  CG  . GLU D 1 44  ? -20.51210 10.49345  -16.44898 1.000 43.93058 ? 42  GLU D CG  1 
ATOM   6500 C  CD  . GLU D 1 44  ? -20.83197 9.00198   -16.41177 1.000 54.77571 ? 42  GLU D CD  1 
ATOM   6501 O  OE1 . GLU D 1 44  ? -20.11773 8.23670   -15.71753 1.000 51.24992 ? 42  GLU D OE1 1 
ATOM   6502 O  OE2 . GLU D 1 44  ? -21.79627 8.58691   -17.09381 1.000 58.59956 ? 42  GLU D OE2 1 
ATOM   6503 N  N   . THR D 1 45  ? -16.29314 12.88852  -16.16855 1.000 44.55999 ? 43  THR D N   1 
ATOM   6504 C  CA  . THR D 1 45  ? -15.06625 13.17022  -15.43633 1.000 42.77886 ? 43  THR D CA  1 
ATOM   6505 C  C   . THR D 1 45  ? -15.22302 14.46600  -14.65632 1.000 43.57966 ? 43  THR D C   1 
ATOM   6506 O  O   . THR D 1 45  ? -15.86776 15.41086  -15.11443 1.000 40.78100 ? 43  THR D O   1 
ATOM   6507 C  CB  . THR D 1 45  ? -13.86538 13.27086  -16.38386 1.000 42.67048 ? 43  THR D CB  1 
ATOM   6508 O  OG1 . THR D 1 45  ? -14.12861 14.26449  -17.37581 1.000 40.23423 ? 43  THR D OG1 1 
ATOM   6509 C  CG2 . THR D 1 45  ? -13.57220 11.91908  -17.06637 1.000 39.04006 ? 43  THR D CG2 1 
ATOM   6510 N  N   . GLU D 1 46  ? -14.64674 14.49180  -13.45901 1.000 43.88781 ? 44  GLU D N   1 
ATOM   6511 C  CA  . GLU D 1 46  ? -14.70877 15.65003  -12.58428 1.000 45.15694 ? 44  GLU D CA  1 
ATOM   6512 C  C   . GLU D 1 46  ? -13.36748 16.35708  -12.46629 1.000 44.06922 ? 44  GLU D C   1 
ATOM   6513 O  O   . GLU D 1 46  ? -13.28329 17.40250  -11.81208 1.000 43.56818 ? 44  GLU D O   1 
ATOM   6514 C  CB  . GLU D 1 46  ? -15.19384 15.23883  -11.18244 1.000 52.05555 ? 44  GLU D CB  1 
ATOM   6515 C  CG  . GLU D 1 46  ? -16.64765 14.75935  -11.11833 1.000 56.87779 ? 44  GLU D CG  1 
ATOM   6516 C  CD  . GLU D 1 46  ? -16.94196 13.93742  -9.86601  1.000 63.43033 ? 44  GLU D CD  1 
ATOM   6517 O  OE1 . GLU D 1 46  ? -16.99686 14.52380  -8.76177  1.000 70.76347 ? 44  GLU D OE1 1 
ATOM   6518 O  OE2 . GLU D 1 46  ? -17.11248 12.70549  -9.97951  1.000 65.67172 ? 44  GLU D OE2 1 
ATOM   6519 N  N   . HIS D 1 47  ? -12.31751 15.81949  -13.08645 1.000 39.55838 ? 45  HIS D N   1 
ATOM   6520 C  CA  . HIS D 1 47  ? -10.99537 16.43193  -13.06356 1.000 40.94884 ? 45  HIS D CA  1 
ATOM   6521 C  C   . HIS D 1 47  ? -10.27016 15.99454  -14.32999 1.000 35.90603 ? 45  HIS D C   1 
ATOM   6522 O  O   . HIS D 1 47  ? -10.46095 14.85439  -14.76071 1.000 35.69418 ? 45  HIS D O   1 
ATOM   6523 C  CB  . HIS D 1 47  ? -10.19864 16.00902  -11.83282 1.000 36.02103 ? 45  HIS D CB  1 
ATOM   6524 C  CG  . HIS D 1 47  ? -9.03112  16.89355  -11.55687 1.000 37.88044 ? 45  HIS D CG  1 
ATOM   6525 N  ND1 . HIS D 1 47  ? -7.83325  16.76543  -12.22555 1.000 37.55681 ? 45  HIS D ND1 1 
ATOM   6526 C  CD2 . HIS D 1 47  ? -8.88193  17.93917  -10.70884 1.000 36.65297 ? 45  HIS D CD2 1 
ATOM   6527 C  CE1 . HIS D 1 47  ? -6.99079  17.68783  -11.79485 1.000 33.89287 ? 45  HIS D CE1 1 
ATOM   6528 N  NE2 . HIS D 1 47  ? -7.60132  18.41029  -10.87074 1.000 37.51109 ? 45  HIS D NE2 1 
ATOM   6529 N  N   . PRO D 1 48  ? -9.47044  16.86163  -14.95771 1.000 35.44676 ? 46  PRO D N   1 
ATOM   6530 C  CA  . PRO D 1 48  ? -8.77108  16.45021  -16.18402 1.000 34.46076 ? 46  PRO D CA  1 
ATOM   6531 C  C   . PRO D 1 48  ? -7.68575  15.41816  -15.95244 1.000 34.01040 ? 46  PRO D C   1 
ATOM   6532 O  O   . PRO D 1 48  ? -7.19903  14.83776  -16.92944 1.000 36.52634 ? 46  PRO D O   1 
ATOM   6533 C  CB  . PRO D 1 48  ? -8.16942  17.76311  -16.71070 1.000 30.69840 ? 46  PRO D CB  1 
ATOM   6534 C  CG  . PRO D 1 48  ? -8.02271  18.61003  -15.50885 1.000 33.76361 ? 46  PRO D CG  1 
ATOM   6535 C  CD  . PRO D 1 48  ? -9.13585  18.24533  -14.57548 1.000 35.22653 ? 46  PRO D CD  1 
ATOM   6536 N  N   . ASP D 1 49  ? -7.27754  15.16877  -14.71528 1.000 31.73032 ? 47  ASP D N   1 
ATOM   6537 C  CA  . ASP D 1 49  ? -6.30992  14.12078  -14.45968 1.000 32.06804 ? 47  ASP D CA  1 
ATOM   6538 C  C   . ASP D 1 49  ? -6.96471  12.80786  -14.04282 1.000 33.64027 ? 47  ASP D C   1 
ATOM   6539 O  O   . ASP D 1 49  ? -6.24960  11.84473  -13.78855 1.000 31.43430 ? 47  ASP D O   1 
ATOM   6540 C  CB  . ASP D 1 49  ? -5.31455  14.57767  -13.39203 1.000 32.70465 ? 47  ASP D CB  1 
ATOM   6541 C  CG  . ASP D 1 49  ? -4.37786  15.67428  -13.89633 1.000 32.68671 ? 47  ASP D CG  1 
ATOM   6542 O  OD1 . ASP D 1 49  ? -3.93517  15.61966  -15.07967 1.000 28.12370 ? 47  ASP D OD1 1 
ATOM   6543 O  OD2 . ASP D 1 49  ? -4.10093  16.60388  -13.11109 1.000 30.93280 ? 47  ASP D OD2 1 
ATOM   6544 N  N   . GLN D 1 50  ? -8.30139  12.75296  -13.96123 1.000 31.71124 ? 48  GLN D N   1 
ATOM   6545 C  CA  . GLN D 1 50  ? -8.98707  11.51865  -13.57240 1.000 33.91710 ? 48  GLN D CA  1 
ATOM   6546 C  C   . GLN D 1 50  ? -8.63121  10.34617  -14.49192 1.000 32.11705 ? 48  GLN D C   1 
ATOM   6547 O  O   . GLN D 1 50  ? -8.35669  9.23431   -14.01789 1.000 29.59119 ? 48  GLN D O   1 
ATOM   6548 C  CB  . GLN D 1 50  ? -10.49862 11.74427  -13.56844 1.000 32.91664 ? 48  GLN D CB  1 
ATOM   6549 C  CG  . GLN D 1 50  ? -11.23832 10.76621  -12.67610 1.000 35.51558 ? 48  GLN D CG  1 
ATOM   6550 C  CD  . GLN D 1 50  ? -12.73965 10.98359  -12.68495 1.000 40.86229 ? 48  GLN D CD  1 
ATOM   6551 O  OE1 . GLN D 1 50  ? -13.22047 12.12558  -12.58626 1.000 42.81048 ? 48  GLN D OE1 1 
ATOM   6552 N  NE2 . GLN D 1 50  ? -13.49703 9.88098   -12.78219 1.000 42.19661 ? 48  GLN D NE2 1 
ATOM   6553 N  N   . ARG D 1 51  ? -8.62253  10.57906  -15.80970 1.000 30.27670 ? 49  ARG D N   1 
ATOM   6554 C  CA  . ARG D 1 51  ? -8.35812  9.49867   -16.75006 1.000 29.45115 ? 49  ARG D CA  1 
ATOM   6555 C  C   . ARG D 1 51  ? -6.95728  8.91957   -16.56045 1.000 30.80322 ? 49  ARG D C   1 
ATOM   6556 O  O   . ARG D 1 51  ? -6.79155  7.69953   -16.48984 1.000 29.94096 ? 49  ARG D O   1 
ATOM   6557 C  CB  . ARG D 1 51  ? -8.56054  9.99209   -18.17446 1.000 31.67774 ? 49  ARG D CB  1 
ATOM   6558 C  CG  . ARG D 1 51  ? -9.99391  9.86038   -18.65648 1.000 37.49124 ? 49  ARG D CG  1 
ATOM   6559 C  CD  . ARG D 1 51  ? -10.33227 8.41313   -19.03325 1.000 37.82851 ? 49  ARG D CD  1 
ATOM   6560 N  NE  . ARG D 1 51  ? -11.58485 8.37696   -19.77458 1.000 39.42410 ? 49  ARG D NE  1 
ATOM   6561 C  CZ  . ARG D 1 51  ? -11.67543 8.64196   -21.07400 1.000 42.16150 ? 49  ARG D CZ  1 
ATOM   6562 N  NH1 . ARG D 1 51  ? -10.60529 8.91967   -21.79553 1.000 39.40072 ? 49  ARG D NH1 1 
ATOM   6563 N  NH2 . ARG D 1 51  ? -12.87398 8.65848   -21.65763 1.000 41.56716 ? 49  ARG D NH2 1 
ATOM   6564 N  N   . PHE D 1 52  ? -5.93847  9.78035   -16.45905 1.000 33.28265 ? 50  PHE D N   1 
ATOM   6565 C  CA  . PHE D 1 52  ? -4.58559  9.31691   -16.15282 1.000 29.38167 ? 50  PHE D CA  1 
ATOM   6566 C  C   . PHE D 1 52  ? -4.57410  8.42706   -14.91672 1.000 30.85965 ? 50  PHE D C   1 
ATOM   6567 O  O   . PHE D 1 52  ? -3.99228  7.33791   -14.93351 1.000 29.00460 ? 50  PHE D O   1 
ATOM   6568 C  CB  . PHE D 1 52  ? -3.66074  10.51427  -15.94393 1.000 29.14046 ? 50  PHE D CB  1 
ATOM   6569 C  CG  . PHE D 1 52  ? -2.21401  10.15539  -15.69577 1.000 29.11343 ? 50  PHE D CG  1 
ATOM   6570 C  CD1 . PHE D 1 52  ? -1.52916  9.30050   -16.56770 1.000 31.24340 ? 50  PHE D CD1 1 
ATOM   6571 C  CD2 . PHE D 1 52  ? -1.51654  10.72463  -14.63625 1.000 31.25127 ? 50  PHE D CD2 1 
ATOM   6572 C  CE1 . PHE D 1 52  ? -0.19497  9.00125   -16.35731 1.000 30.44825 ? 50  PHE D CE1 1 
ATOM   6573 C  CE2 . PHE D 1 52  ? -0.17554  10.44496  -14.42493 1.000 28.27437 ? 50  PHE D CE2 1 
ATOM   6574 C  CZ  . PHE D 1 52  ? 0.48459   9.57873   -15.28996 1.000 33.01074 ? 50  PHE D CZ  1 
ATOM   6575 N  N   . PHE D 1 53  ? -5.18354  8.91063   -13.82308 1.000 30.02624 ? 51  PHE D N   1 
ATOM   6576 C  CA  . PHE D 1 53  ? -5.35115  8.12403   -12.59798 1.000 31.37743 ? 51  PHE D CA  1 
ATOM   6577 C  C   . PHE D 1 53  ? -5.94938  6.74379   -12.89213 1.000 30.67224 ? 51  PHE D C   1 
ATOM   6578 O  O   . PHE D 1 53  ? -5.35419  5.70236   -12.55766 1.000 30.33079 ? 51  PHE D O   1 
ATOM   6579 C  CB  . PHE D 1 53  ? -6.23632  8.93553   -11.63855 1.000 29.53489 ? 51  PHE D CB  1 
ATOM   6580 C  CG  . PHE D 1 53  ? -6.42863  8.32989   -10.26059 1.000 31.99932 ? 51  PHE D CG  1 
ATOM   6581 C  CD1 . PHE D 1 53  ? -7.46842  7.45253   -10.01437 1.000 30.22941 ? 51  PHE D CD1 1 
ATOM   6582 C  CD2 . PHE D 1 53  ? -5.62632  8.71986   -9.20083  1.000 34.15529 ? 51  PHE D CD2 1 
ATOM   6583 C  CE1 . PHE D 1 53  ? -7.67783  6.92395   -8.73505  1.000 35.09354 ? 51  PHE D CE1 1 
ATOM   6584 C  CE2 . PHE D 1 53  ? -5.81509  8.19889   -7.92439  1.000 33.20035 ? 51  PHE D CE2 1 
ATOM   6585 C  CZ  . PHE D 1 53  ? -6.85133  7.30016   -7.68708  1.000 34.49413 ? 51  PHE D CZ  1 
ATOM   6586 N  N   . GLN D 1 54  ? -7.09756  6.70958   -13.57964 1.000 28.30908 ? 52  GLN D N   1 
ATOM   6587 C  CA  . GLN D 1 54  ? -7.77437  5.43411   -13.82319 1.000 28.73529 ? 52  GLN D CA  1 
ATOM   6588 C  C   . GLN D 1 54  ? -6.90019  4.47459   -14.64170 1.000 32.30625 ? 52  GLN D C   1 
ATOM   6589 O  O   . GLN D 1 54  ? -6.73009  3.29545   -14.29071 1.000 26.71737 ? 52  GLN D O   1 
ATOM   6590 C  CB  . GLN D 1 54  ? -9.10584  5.67903   -14.54850 1.000 31.55987 ? 52  GLN D CB  1 
ATOM   6591 C  CG  . GLN D 1 54  ? -9.84669  4.35352   -14.91671 1.000 30.23112 ? 52  GLN D CG  1 
ATOM   6592 C  CD  . GLN D 1 54  ? -11.14231 4.56580   -15.72377 1.000 36.15116 ? 52  GLN D CD  1 
ATOM   6593 O  OE1 . GLN D 1 54  ? -11.32707 5.59184   -16.39699 1.000 34.41062 ? 52  GLN D OE1 1 
ATOM   6594 N  NE2 . GLN D 1 54  ? -12.03779 3.57870   -15.66681 1.000 33.13910 ? 52  GLN D NE2 1 
ATOM   6595 N  N   . VAL D 1 55  ? -6.32926  4.97427   -15.74478 1.000 31.42468 ? 53  VAL D N   1 
ATOM   6596 C  CA  . VAL D 1 55  ? -5.62569  4.10248   -16.67995 1.000 27.65779 ? 53  VAL D CA  1 
ATOM   6597 C  C   . VAL D 1 55  ? -4.40801  3.47640   -16.01570 1.000 27.07454 ? 53  VAL D C   1 
ATOM   6598 O  O   . VAL D 1 55  ? -4.07904  2.31082   -16.26335 1.000 26.69233 ? 53  VAL D O   1 
ATOM   6599 C  CB  . VAL D 1 55  ? -5.22865  4.91049   -17.94004 1.000 28.45085 ? 53  VAL D CB  1 
ATOM   6600 C  CG1 . VAL D 1 55  ? -4.17654  4.16950   -18.73883 1.000 32.08983 ? 53  VAL D CG1 1 
ATOM   6601 C  CG2 . VAL D 1 55  ? -6.43315  5.17197   -18.79414 1.000 28.51292 ? 53  VAL D CG2 1 
ATOM   6602 N  N   . THR D 1 56  ? -3.68622  4.24121   -15.19621 1.000 27.44449 ? 54  THR D N   1 
ATOM   6603 C  CA  . THR D 1 56  ? -2.50204  3.65549   -14.57471 1.000 29.53873 ? 54  THR D CA  1 
ATOM   6604 C  C   . THR D 1 56  ? -2.88597  2.48002   -13.67970 1.000 28.82337 ? 54  THR D C   1 
ATOM   6605 O  O   . THR D 1 56  ? -2.14079  1.50160   -13.59837 1.000 27.65170 ? 54  THR D O   1 
ATOM   6606 C  CB  . THR D 1 56  ? -1.70431  4.69534   -13.78480 1.000 29.59953 ? 54  THR D CB  1 
ATOM   6607 O  OG1 . THR D 1 56  ? -2.52432  5.28487   -12.76238 1.000 32.06748 ? 54  THR D OG1 1 
ATOM   6608 C  CG2 . THR D 1 56  ? -1.21613  5.78946   -14.69300 1.000 29.73887 ? 54  THR D CG2 1 
ATOM   6609 N  N   . HIS D 1 57  ? -4.06032  2.54366   -13.03130 1.000 26.88600 ? 55  HIS D N   1 
ATOM   6610 C  CA  . HIS D 1 57  ? -4.53141  1.41353   -12.22641 1.000 29.57452 ? 55  HIS D CA  1 
ATOM   6611 C  C   . HIS D 1 57  ? -4.96241  0.24855   -13.11636 1.000 27.92587 ? 55  HIS D C   1 
ATOM   6612 O  O   . HIS D 1 57  ? -4.64959  -0.90627  -12.82908 1.000 27.62034 ? 55  HIS D O   1 
ATOM   6613 C  CB  . HIS D 1 57  ? -5.71122  1.80720   -11.33062 1.000 29.96283 ? 55  HIS D CB  1 
ATOM   6614 C  CG  . HIS D 1 57  ? -5.36097  2.65835   -10.14495 1.000 32.53809 ? 55  HIS D CG  1 
ATOM   6615 N  ND1 . HIS D 1 57  ? -5.29197  4.03973   -10.21020 1.000 30.68483 ? 55  HIS D ND1 1 
ATOM   6616 C  CD2 . HIS D 1 57  ? -5.15760  2.33309   -8.84358  1.000 30.66521 ? 55  HIS D CD2 1 
ATOM   6617 C  CE1 . HIS D 1 57  ? -5.01626  4.52291   -9.01174  1.000 31.32309 ? 55  HIS D CE1 1 
ATOM   6618 N  NE2 . HIS D 1 57  ? -4.93616  3.51008   -8.16249  1.000 30.31518 ? 55  HIS D NE2 1 
ATOM   6619 N  N   . LEU D 1 58  ? -5.71766  0.52895   -14.18595 1.000 28.88893 ? 56  LEU D N   1 
ATOM   6620 C  CA  . LEU D 1 58  ? -6.18042  -0.54308  -15.06691 1.000 28.50491 ? 56  LEU D CA  1 
ATOM   6621 C  C   . LEU D 1 58  ? -5.00853  -1.27492  -15.71545 1.000 28.72224 ? 56  LEU D C   1 
ATOM   6622 O  O   . LEU D 1 58  ? -5.03365  -2.50229  -15.87832 1.000 29.27048 ? 56  LEU D O   1 
ATOM   6623 C  CB  . LEU D 1 58  ? -7.09537  0.03318   -16.13875 1.000 31.91997 ? 56  LEU D CB  1 
ATOM   6624 C  CG  . LEU D 1 58  ? -8.41521  0.63766   -15.66248 1.000 30.58628 ? 56  LEU D CG  1 
ATOM   6625 C  CD1 . LEU D 1 58  ? -9.30838  0.94526   -16.85127 1.000 29.70964 ? 56  LEU D CD1 1 
ATOM   6626 C  CD2 . LEU D 1 58  ? -9.09333  -0.33675  -14.73567 1.000 31.06526 ? 56  LEU D CD2 1 
ATOM   6627 N  N   . ILE D 1 59  ? -3.98189  -0.53618  -16.11797 1.000 31.37237 ? 57  ILE D N   1 
ATOM   6628 C  CA  . ILE D 1 59  ? -2.78888  -1.18390  -16.65143 1.000 31.13803 ? 57  ILE D CA  1 
ATOM   6629 C  C   . ILE D 1 59  ? -2.16785  -2.07755  -15.58831 1.000 30.04306 ? 57  ILE D C   1 
ATOM   6630 O  O   . ILE D 1 59  ? -1.75461  -3.20887  -15.86481 1.000 28.77592 ? 57  ILE D O   1 
ATOM   6631 C  CB  . ILE D 1 59  ? -1.80284  -0.12073  -17.17108 1.000 30.40652 ? 57  ILE D CB  1 
ATOM   6632 C  CG1 . ILE D 1 59  ? -2.27924  0.41914   -18.51680 1.000 29.77492 ? 57  ILE D CG1 1 
ATOM   6633 C  CG2 . ILE D 1 59  ? -0.38721  -0.69177  -17.29864 1.000 28.62342 ? 57  ILE D CG2 1 
ATOM   6634 C  CD1 . ILE D 1 59  ? -1.53374  1.70415   -18.99187 1.000 24.98924 ? 57  ILE D CD1 1 
ATOM   6635 N  N   . THR D 1 60  ? -2.11594  -1.59737  -14.34958 1.000 29.86196 ? 58  THR D N   1 
ATOM   6636 C  CA  . THR D 1 60  ? -1.51296  -2.39126  -13.29310 1.000 28.90594 ? 58  THR D CA  1 
ATOM   6637 C  C   . THR D 1 60  ? -2.28539  -3.68328  -13.08799 1.000 29.45062 ? 58  THR D C   1 
ATOM   6638 O  O   . THR D 1 60  ? -1.69516  -4.76320  -12.95853 1.000 27.58548 ? 58  THR D O   1 
ATOM   6639 C  CB  . THR D 1 60  ? -1.47611  -1.61328  -11.98269 1.000 28.28983 ? 58  THR D CB  1 
ATOM   6640 O  OG1 . THR D 1 60  ? -0.68477  -0.42299  -12.15107 1.000 28.86878 ? 58  THR D OG1 1 
ATOM   6641 C  CG2 . THR D 1 60  ? -0.85438  -2.50967  -10.89677 1.000 27.46550 ? 58  THR D CG2 1 
ATOM   6642 N  N   . GLU D 1 61  ? -3.61605  -3.57500  -13.03577 1.000 29.76559 ? 59  GLU D N   1 
ATOM   6643 C  CA  . GLU D 1 61  ? -4.44652  -4.72639  -12.73991 1.000 31.41047 ? 59  GLU D CA  1 
ATOM   6644 C  C   . GLU D 1 61  ? -4.39445  -5.74790  -13.86538 1.000 28.48523 ? 59  GLU D C   1 
ATOM   6645 O  O   . GLU D 1 61  ? -4.47563  -6.93648  -13.59142 1.000 28.65214 ? 59  GLU D O   1 
ATOM   6646 C  CB  . GLU D 1 61  ? -5.89546  -4.30099  -12.46356 1.000 24.45314 ? 59  GLU D CB  1 
ATOM   6647 C  CG  . GLU D 1 61  ? -6.08686  -3.48127  -11.16779 1.000 29.82156 ? 59  GLU D CG  1 
ATOM   6648 C  CD  . GLU D 1 61  ? -5.95528  -4.28629  -9.86833  1.000 29.90525 ? 59  GLU D CD  1 
ATOM   6649 O  OE1 . GLU D 1 61  ? -5.95798  -5.52884  -9.91132  1.000 32.15995 ? 59  GLU D OE1 1 
ATOM   6650 O  OE2 . GLU D 1 61  ? -5.83681  -3.65640  -8.79154  1.000 29.73093 ? 59  GLU D OE2 1 
ATOM   6651 N  N   . TYR D 1 62  ? -4.28581  -5.29697  -15.12552 1.000 28.61127 ? 60  TYR D N   1 
ATOM   6652 C  CA  . TYR D 1 62  ? -4.09719  -6.21877  -16.23660 1.000 27.22410 ? 60  TYR D CA  1 
ATOM   6653 C  C   . TYR D 1 62  ? -2.76828  -6.96027  -16.09428 1.000 28.59176 ? 60  TYR D C   1 
ATOM   6654 O  O   . TYR D 1 62  ? -2.70117  -8.17528  -16.30523 1.000 28.40127 ? 60  TYR D O   1 
ATOM   6655 C  CB  . TYR D 1 62  ? -4.14210  -5.45981  -17.57355 1.000 32.50270 ? 60  TYR D CB  1 
ATOM   6656 C  CG  . TYR D 1 62  ? -5.52743  -5.30505  -18.16460 1.000 34.09812 ? 60  TYR D CG  1 
ATOM   6657 C  CD1 . TYR D 1 62  ? -6.56421  -6.13243  -17.77247 1.000 38.98287 ? 60  TYR D CD1 1 
ATOM   6658 C  CD2 . TYR D 1 62  ? -5.79809  -4.33321  -19.11503 1.000 38.75721 ? 60  TYR D CD2 1 
ATOM   6659 C  CE1 . TYR D 1 62  ? -7.83724  -6.00395  -18.30246 1.000 37.09243 ? 60  TYR D CE1 1 
ATOM   6660 C  CE2 . TYR D 1 62  ? -7.07714  -4.20398  -19.65305 1.000 38.87315 ? 60  TYR D CE2 1 
ATOM   6661 C  CZ  . TYR D 1 62  ? -8.08795  -5.04776  -19.23149 1.000 36.43915 ? 60  TYR D CZ  1 
ATOM   6662 O  OH  . TYR D 1 62  ? -9.34481  -4.92977  -19.76308 1.000 37.97906 ? 60  TYR D OH  1 
ATOM   6663 N  N   . ALA D 1 63  ? -1.70019  -6.25547  -15.69472 1.000 26.59063 ? 61  ALA D N   1 
ATOM   6664 C  CA  . ALA D 1 63  ? -0.43080  -6.96222  -15.55847 1.000 27.40131 ? 61  ALA D CA  1 
ATOM   6665 C  C   . ALA D 1 63  ? -0.49046  -7.98028  -14.43438 1.000 29.19986 ? 61  ALA D C   1 
ATOM   6666 O  O   . ALA D 1 63  ? 0.03929   -9.09197  -14.57658 1.000 30.38309 ? 61  ALA D O   1 
ATOM   6667 C  CB  . ALA D 1 63  ? 0.71761   -5.98993  -15.32576 1.000 24.82788 ? 61  ALA D CB  1 
ATOM   6668 N  N   . TRP D 1 64  ? -1.16590  -7.63741  -13.32106 1.000 26.91452 ? 62  TRP D N   1 
ATOM   6669 C  CA  . TRP D 1 64  ? -1.22480  -8.54489  -12.17054 1.000 27.34992 ? 62  TRP D CA  1 
ATOM   6670 C  C   . TRP D 1 64  ? -2.11760  -9.75917  -12.43342 1.000 30.07283 ? 62  TRP D C   1 
ATOM   6671 O  O   . TRP D 1 64  ? -1.82144  -10.86120 -11.95686 1.000 27.73004 ? 62  TRP D O   1 
ATOM   6672 C  CB  . TRP D 1 64  ? -1.73194  -7.81312  -10.91894 1.000 28.61648 ? 62  TRP D CB  1 
ATOM   6673 C  CG  . TRP D 1 64  ? -0.66284  -7.10849  -10.19323 1.000 27.54030 ? 62  TRP D CG  1 
ATOM   6674 C  CD1 . TRP D 1 64  ? 0.67123   -7.35435  -10.28722 1.000 29.81122 ? 62  TRP D CD1 1 
ATOM   6675 C  CD2 . TRP D 1 64  ? -0.81187  -6.00630  -9.29006  1.000 28.95614 ? 62  TRP D CD2 1 
ATOM   6676 N  NE1 . TRP D 1 64  ? 1.37509   -6.47346  -9.49145  1.000 29.09263 ? 62  TRP D NE1 1 
ATOM   6677 C  CE2 . TRP D 1 64  ? 0.48616   -5.63989  -8.86412  1.000 30.17923 ? 62  TRP D CE2 1 
ATOM   6678 C  CE3 . TRP D 1 64  ? -1.91418  -5.30469  -8.78594  1.000 28.64592 ? 62  TRP D CE3 1 
ATOM   6679 C  CZ2 . TRP D 1 64  ? 0.71498   -4.60558  -7.96104  1.000 27.95858 ? 62  TRP D CZ2 1 
ATOM   6680 C  CZ3 . TRP D 1 64  ? -1.69026  -4.25484  -7.89499  1.000 28.34578 ? 62  TRP D CZ3 1 
ATOM   6681 C  CH2 . TRP D 1 64  ? -0.38616  -3.92555  -7.48277  1.000 29.52695 ? 62  TRP D CH2 1 
ATOM   6682 N  N   . VAL D 1 65  ? -3.24520  -9.59101  -13.13017 1.000 28.49425 ? 63  VAL D N   1 
ATOM   6683 C  CA  . VAL D 1 65  ? -4.01395  -10.80031 -13.44721 1.000 31.07856 ? 63  VAL D CA  1 
ATOM   6684 C  C   . VAL D 1 65  ? -3.21282  -11.71282 -14.37810 1.000 30.79921 ? 63  VAL D C   1 
ATOM   6685 O  O   . VAL D 1 65  ? -3.31584  -12.95011 -14.29865 1.000 28.30482 ? 63  VAL D O   1 
ATOM   6686 C  CB  . VAL D 1 65  ? -5.40165  -10.46642 -14.04688 1.000 32.08208 ? 63  VAL D CB  1 
ATOM   6687 C  CG1 . VAL D 1 65  ? -5.27093  -9.79074  -15.42133 1.000 33.73189 ? 63  VAL D CG1 1 
ATOM   6688 C  CG2 . VAL D 1 65  ? -6.22726  -11.76701 -14.19065 1.000 33.49559 ? 63  VAL D CG2 1 
ATOM   6689 N  N   . GLN D 1 66  ? -2.38769  -11.13194 -15.25866 1.000 31.59525 ? 64  GLN D N   1 
ATOM   6690 C  CA  . GLN D 1 66  ? -1.53163  -11.97218 -16.09240 1.000 28.80971 ? 64  GLN D CA  1 
ATOM   6691 C  C   . GLN D 1 66  ? -0.44116  -12.63316 -15.25453 1.000 29.51944 ? 64  GLN D C   1 
ATOM   6692 O  O   . GLN D 1 66  ? -0.11441  -13.80237 -15.46749 1.000 29.60746 ? 64  GLN D O   1 
ATOM   6693 C  CB  . GLN D 1 66  ? -0.91508  -11.16441 -17.24729 1.000 26.00312 ? 64  GLN D CB  1 
ATOM   6694 C  CG  . GLN D 1 66  ? -0.37014  -12.09537 -18.36760 1.000 29.60446 ? 64  GLN D CG  1 
ATOM   6695 C  CD  . GLN D 1 66  ? -1.41313  -13.07941 -18.88555 1.000 30.69861 ? 64  GLN D CD  1 
ATOM   6696 O  OE1 . GLN D 1 66  ? -2.58190  -12.70201 -19.09963 1.000 29.66397 ? 64  GLN D OE1 1 
ATOM   6697 N  NE2 . GLN D 1 66  ? -1.00263  -14.35805 -19.09991 1.000 27.46336 ? 64  GLN D NE2 1 
ATOM   6698 N  N   . VAL D 1 67  ? 0.09782   -11.91822 -14.26382 1.000 31.29221 ? 65  VAL D N   1 
ATOM   6699 C  CA  . VAL D 1 67  ? 1.06533   -12.52698 -13.35146 1.000 30.61780 ? 65  VAL D CA  1 
ATOM   6700 C  C   . VAL D 1 67  ? 0.45429   -13.76023 -12.69621 1.000 31.37741 ? 65  VAL D C   1 
ATOM   6701 O  O   . VAL D 1 67  ? 1.07811   -14.82976 -12.62951 1.000 28.47163 ? 65  VAL D O   1 
ATOM   6702 C  CB  . VAL D 1 67  ? 1.52891   -11.50513 -12.29603 1.000 31.90304 ? 65  VAL D CB  1 
ATOM   6703 C  CG1 . VAL D 1 67  ? 2.18975   -12.22197 -11.12145 1.000 31.73977 ? 65  VAL D CG1 1 
ATOM   6704 C  CG2 . VAL D 1 67  ? 2.47650   -10.44650 -12.92675 1.000 27.54882 ? 65  VAL D CG2 1 
ATOM   6705 N  N   . HIS D 1 68  ? -0.79408  -13.62167 -12.23279 1.000 31.82536 ? 66  HIS D N   1 
ATOM   6706 C  CA  . HIS D 1 68  ? -1.52040  -14.71796 -11.59689 1.000 33.06362 ? 66  HIS D CA  1 
ATOM   6707 C  C   . HIS D 1 68  ? -1.68029  -15.91079 -12.53112 1.000 33.75069 ? 66  HIS D C   1 
ATOM   6708 O  O   . HIS D 1 68  ? -1.44714  -17.06385 -12.13969 1.000 29.96479 ? 66  HIS D O   1 
ATOM   6709 C  CB  . HIS D 1 68  ? -2.90419  -14.25143 -11.15252 1.000 28.13493 ? 66  HIS D CB  1 
ATOM   6710 C  CG  . HIS D 1 68  ? -3.49952  -15.10089 -10.06601 1.000 33.35305 ? 66  HIS D CG  1 
ATOM   6711 N  ND1 . HIS D 1 68  ? -4.40855  -16.10776 -10.33886 1.000 36.87530 ? 66  HIS D ND1 1 
ATOM   6712 C  CD2 . HIS D 1 68  ? -3.39441  -15.04921 -8.71535  1.000 35.04668 ? 66  HIS D CD2 1 
ATOM   6713 C  CE1 . HIS D 1 68  ? -4.79709  -16.67071 -9.20798  1.000 33.71298 ? 66  HIS D CE1 1 
ATOM   6714 N  NE2 . HIS D 1 68  ? -4.21158  -16.03682 -8.20685  1.000 32.65185 ? 66  HIS D NE2 1 
ATOM   6715 N  N   . TYR D 1 69  ? -2.11791  -15.65098 -13.76363 1.000 31.67208 ? 67  TYR D N   1 
ATOM   6716 C  CA  . TYR D 1 69  ? -2.28025  -16.71948 -14.74242 1.000 30.74815 ? 67  TYR D CA  1 
ATOM   6717 C  C   . TYR D 1 69  ? -0.98591  -17.49308 -14.95677 1.000 29.44415 ? 67  TYR D C   1 
ATOM   6718 O  O   . TYR D 1 69  ? -0.98221  -18.73274 -15.03384 1.000 31.64697 ? 67  TYR D O   1 
ATOM   6719 C  CB  . TYR D 1 69  ? -2.74567  -16.09799 -16.03971 1.000 31.32592 ? 67  TYR D CB  1 
ATOM   6720 C  CG  . TYR D 1 69  ? -3.23306  -17.04111 -17.08025 1.000 29.26147 ? 67  TYR D CG  1 
ATOM   6721 C  CD1 . TYR D 1 69  ? -4.56057  -17.42867 -17.11070 1.000 31.53438 ? 67  TYR D CD1 1 
ATOM   6722 C  CD2 . TYR D 1 69  ? -2.38803  -17.48578 -18.08274 1.000 28.01893 ? 67  TYR D CD2 1 
ATOM   6723 C  CE1 . TYR D 1 69  ? -5.02339  -18.24463 -18.09077 1.000 32.32998 ? 67  TYR D CE1 1 
ATOM   6724 C  CE2 . TYR D 1 69  ? -2.84366  -18.30851 -19.05714 1.000 31.65144 ? 67  TYR D CE2 1 
ATOM   6725 C  CZ  . TYR D 1 69  ? -4.16298  -18.68874 -19.05591 1.000 29.56632 ? 67  TYR D CZ  1 
ATOM   6726 O  OH  . TYR D 1 69  ? -4.61879  -19.50361 -20.04236 1.000 31.74982 ? 67  TYR D OH  1 
ATOM   6727 N  N   . GLU D 1 70  ? 0.12122   -16.77702 -15.10742 1.000 30.56234 ? 68  GLU D N   1 
ATOM   6728 C  CA  . GLU D 1 70  ? 1.37843   -17.45200 -15.38449 1.000 30.87835 ? 68  GLU D CA  1 
ATOM   6729 C  C   . GLU D 1 70  ? 1.91662   -18.17081 -14.14482 1.000 32.28499 ? 68  GLU D C   1 
ATOM   6730 O  O   . GLU D 1 70  ? 2.56156   -19.21256 -14.27607 1.000 28.50204 ? 68  GLU D O   1 
ATOM   6731 C  CB  . GLU D 1 70  ? 2.40439   -16.45469 -15.96593 1.000 32.84601 ? 68  GLU D CB  1 
ATOM   6732 C  CG  . GLU D 1 70  ? 1.91829   -15.60811 -17.16137 1.000 28.84427 ? 68  GLU D CG  1 
ATOM   6733 C  CD  . GLU D 1 70  ? 1.63749   -16.43349 -18.41365 1.000 31.78057 ? 68  GLU D CD  1 
ATOM   6734 O  OE1 . GLU D 1 70  ? 1.67804   -17.66064 -18.33434 1.000 33.77876 ? 68  GLU D OE1 1 
ATOM   6735 O  OE2 . GLU D 1 70  ? 1.37993   -15.86355 -19.49766 1.000 31.25682 ? 68  GLU D OE2 1 
ATOM   6736 N  N   . LEU D 1 71  ? 1.64565   -17.65317 -12.93975 1.000 31.56378 ? 69  LEU D N   1 
ATOM   6737 C  CA  . LEU D 1 71  ? 2.05472   -18.36083 -11.72469 1.000 28.67770 ? 69  LEU D CA  1 
ATOM   6738 C  C   . LEU D 1 71  ? 1.29775   -19.66676 -11.57062 1.000 27.07439 ? 69  LEU D C   1 
ATOM   6739 O  O   . LEU D 1 71  ? 1.86698   -20.67043 -11.12374 1.000 30.61179 ? 69  LEU D O   1 
ATOM   6740 C  CB  . LEU D 1 71  ? 1.83171   -17.46346 -10.50060 1.000 28.72523 ? 69  LEU D CB  1 
ATOM   6741 C  CG  . LEU D 1 71  ? 2.85055   -16.33615 -10.30639 1.000 31.65033 ? 69  LEU D CG  1 
ATOM   6742 C  CD1 . LEU D 1 71  ? 2.51371   -15.43135 -9.12368  1.000 28.32762 ? 69  LEU D CD1 1 
ATOM   6743 C  CD2 . LEU D 1 71  ? 4.28315   -16.86690 -10.17885 1.000 30.94843 ? 69  LEU D CD2 1 
ATOM   6744 N  N   . ARG D 1 72  ? 0.01608   -19.69016 -11.94916 1.000 28.87310 ? 70  ARG D N   1 
ATOM   6745 C  CA  . ARG D 1 72  ? -0.72985  -20.94831 -11.93013 1.000 28.25345 ? 70  ARG D CA  1 
ATOM   6746 C  C   . ARG D 1 72  ? -0.09593  -21.96165 -12.86923 1.000 32.82962 ? 70  ARG D C   1 
ATOM   6747 O  O   . ARG D 1 72  ? 0.05125   -23.15202 -12.53674 1.000 27.42063 ? 70  ARG D O   1 
ATOM   6748 C  CB  . ARG D 1 72  ? -2.17562  -20.68432 -12.34617 1.000 31.97473 ? 70  ARG D CB  1 
ATOM   6749 C  CG  . ARG D 1 72  ? -3.07933  -20.13735 -11.24708 1.000 34.73861 ? 70  ARG D CG  1 
ATOM   6750 C  CD  . ARG D 1 72  ? -4.35042  -19.58360 -11.84632 1.000 32.92671 ? 70  ARG D CD  1 
ATOM   6751 N  NE  . ARG D 1 72  ? -5.07767  -20.60041 -12.59869 1.000 34.93200 ? 70  ARG D NE  1 
ATOM   6752 C  CZ  . ARG D 1 72  ? -5.89708  -20.33248 -13.60446 1.000 36.37786 ? 70  ARG D CZ  1 
ATOM   6753 N  NH1 . ARG D 1 72  ? -6.07854  -19.09398 -14.03527 1.000 35.61612 ? 70  ARG D NH1 1 
ATOM   6754 N  NH2 . ARG D 1 72  ? -6.55455  -21.32743 -14.19050 1.000 35.77462 ? 70  ARG D NH2 1 
ATOM   6755 N  N   . ARG D 1 73  ? 0.29613   -21.49946 -14.05607 1.000 30.35282 ? 71  ARG D N   1 
ATOM   6756 C  CA  . ARG D 1 73  ? 1.03344   -22.36504 -14.96052 1.000 28.95822 ? 71  ARG D CA  1 
ATOM   6757 C  C   . ARG D 1 73  ? 2.35010   -22.81801 -14.34466 1.000 30.60824 ? 71  ARG D C   1 
ATOM   6758 O  O   . ARG D 1 73  ? 2.76230   -23.97347 -14.53416 1.000 32.75906 ? 71  ARG D O   1 
ATOM   6759 C  CB  . ARG D 1 73  ? 1.28463   -21.64618 -16.28952 1.000 28.86276 ? 71  ARG D CB  1 
ATOM   6760 C  CG  . ARG D 1 73  ? 0.02633   -21.41773 -17.08295 1.000 31.66196 ? 71  ARG D CG  1 
ATOM   6761 C  CD  . ARG D 1 73  ? 0.32717   -20.57231 -18.29291 1.000 32.34173 ? 71  ARG D CD  1 
ATOM   6762 N  NE  . ARG D 1 73  ? 1.10358   -21.31440 -19.27920 1.000 31.15735 ? 71  ARG D NE  1 
ATOM   6763 C  CZ  . ARG D 1 73  ? 1.62920   -20.76535 -20.36636 1.000 32.10230 ? 71  ARG D CZ  1 
ATOM   6764 N  NH1 . ARG D 1 73  ? 1.55384   -19.45528 -20.58111 1.000 31.01311 ? 71  ARG D NH1 1 
ATOM   6765 N  NH2 . ARG D 1 73  ? 2.22464   -21.55048 -21.26907 1.000 32.81303 ? 71  ARG D NH2 1 
ATOM   6766 N  N   . ALA D 1 74  ? 3.03008   -21.93985 -13.60032 1.000 26.91014 ? 72  ALA D N   1 
ATOM   6767 C  CA  . ALA D 1 74  ? 4.29834   -22.38329 -13.01798 1.000 30.26216 ? 72  ALA D CA  1 
ATOM   6768 C  C   . ALA D 1 74  ? 4.07630   -23.48807 -11.96857 1.000 32.04122 ? 72  ALA D C   1 
ATOM   6769 O  O   . ALA D 1 74  ? 4.89106   -24.41424 -11.85185 1.000 31.53518 ? 72  ALA D O   1 
ATOM   6770 C  CB  . ALA D 1 74  ? 5.05090   -21.19206 -12.41697 1.000 29.20949 ? 72  ALA D CB  1 
ATOM   6771 N  N   . ILE D 1 75  ? 2.97311   -23.41736 -11.21323 1.000 29.85614 ? 73  ILE D N   1 
ATOM   6772 C  CA  . ILE D 1 75  ? 2.66551   -24.48897 -10.26045 1.000 32.94460 ? 73  ILE D CA  1 
ATOM   6773 C  C   . ILE D 1 75  ? 2.49032   -25.80738 -10.99277 1.000 31.81173 ? 73  ILE D C   1 
ATOM   6774 O  O   . ILE D 1 75  ? 3.04059   -26.84301 -10.58940 1.000 36.37868 ? 73  ILE D O   1 
ATOM   6775 C  CB  . ILE D 1 75  ? 1.40608   -24.14713 -9.43953  1.000 32.07385 ? 73  ILE D CB  1 
ATOM   6776 C  CG1 . ILE D 1 75  ? 1.69555   -23.00669 -8.47934  1.000 32.38597 ? 73  ILE D CG1 1 
ATOM   6777 C  CG2 . ILE D 1 75  ? 0.88322   -25.44411 -8.66385  1.000 30.05240 ? 73  ILE D CG2 1 
ATOM   6778 C  CD1 . ILE D 1 75  ? 0.39722   -22.32538 -7.92906  1.000 31.02896 ? 73  ILE D CD1 1 
ATOM   6779 N  N   . GLY D 1 76  ? 1.71600   -25.79120 -12.08214 1.000 31.98305 ? 74  GLY D N   1 
ATOM   6780 C  CA  . GLY D 1 76  ? 1.47441   -27.01477 -12.83054 1.000 31.27747 ? 74  GLY D CA  1 
ATOM   6781 C  C   . GLY D 1 76  ? 2.74743   -27.61870 -13.40317 1.000 34.63371 ? 74  GLY D C   1 
ATOM   6782 O  O   . GLY D 1 76  ? 2.88200   -28.83924 -13.47843 1.000 34.43091 ? 74  GLY D O   1 
ATOM   6783 N  N   . HIS D 1 77  ? 3.69154   -26.76828 -13.82001 1.000 33.39432 ? 75  HIS D N   1 
ATOM   6784 C  CA  . HIS D 1 77  ? 4.98492   -27.23203 -14.32448 1.000 33.69614 ? 75  HIS D CA  1 
ATOM   6785 C  C   . HIS D 1 77  ? 5.83209   -27.83168 -13.21273 1.000 32.71075 ? 75  HIS D C   1 
ATOM   6786 O  O   . HIS D 1 77  ? 6.46399   -28.88179 -13.39133 1.000 33.44645 ? 75  HIS D O   1 
ATOM   6787 C  CB  . HIS D 1 77  ? 5.74943   -26.06207 -14.97240 1.000 32.66268 ? 75  HIS D CB  1 
ATOM   6788 C  CG  . HIS D 1 77  ? 5.22086   -25.65237 -16.31079 1.000 34.27743 ? 75  HIS D CG  1 
ATOM   6789 N  ND1 . HIS D 1 77  ? 4.73399   -26.56161 -17.22934 1.000 35.78372 ? 75  HIS D ND1 1 
ATOM   6790 C  CD2 . HIS D 1 77  ? 5.11701   -24.43103 -16.89289 1.000 33.06966 ? 75  HIS D CD2 1 
ATOM   6791 C  CE1 . HIS D 1 77  ? 4.34406   -25.91208 -18.31531 1.000 33.72204 ? 75  HIS D CE1 1 
ATOM   6792 N  NE2 . HIS D 1 77  ? 4.56136   -24.62089 -18.13408 1.000 35.64486 ? 75  HIS D NE2 1 
ATOM   6793 N  N   . LEU D 1 78  ? 5.91777   -27.12792 -12.08194 1.000 33.10495 ? 76  LEU D N   1 
ATOM   6794 C  CA  . LEU D 1 78  ? 6.76072   -27.58298 -10.99112 1.000 32.82338 ? 76  LEU D CA  1 
ATOM   6795 C  C   . LEU D 1 78  ? 6.26181   -28.91643 -10.45064 1.000 34.47668 ? 76  LEU D C   1 
ATOM   6796 O  O   . LEU D 1 78  ? 7.06160   -29.81177 -10.14587 1.000 32.13532 ? 76  LEU D O   1 
ATOM   6797 C  CB  . LEU D 1 78  ? 6.80309   -26.51835 -9.89809  1.000 33.15504 ? 76  LEU D CB  1 
ATOM   6798 C  CG  . LEU D 1 78  ? 7.75381   -25.35593 -10.18956 1.000 31.02196 ? 76  LEU D CG  1 
ATOM   6799 C  CD1 . LEU D 1 78  ? 7.59053   -24.22313 -9.17277  1.000 31.51593 ? 76  LEU D CD1 1 
ATOM   6800 C  CD2 . LEU D 1 78  ? 9.20569   -25.84061 -10.24265 1.000 32.27696 ? 76  LEU D CD2 1 
ATOM   6801 N  N   . ASP D 1 79  ? 4.93821   -29.07912 -10.37578 1.000 33.39882 ? 77  ASP D N   1 
ATOM   6802 C  CA  . ASP D 1 79  ? 4.36002   -30.31061 -9.86111  1.000 35.30213 ? 77  ASP D CA  1 
ATOM   6803 C  C   . ASP D 1 79  ? 4.67574   -31.50294 -10.76701 1.000 37.12005 ? 77  ASP D C   1 
ATOM   6804 O  O   . ASP D 1 79  ? 4.69705   -32.64795 -10.30361 1.000 35.33995 ? 77  ASP D O   1 
ATOM   6805 C  CB  . ASP D 1 79  ? 2.84516   -30.13917 -9.71596  1.000 33.51648 ? 77  ASP D CB  1 
ATOM   6806 C  CG  . ASP D 1 79  ? 2.43501   -29.34308 -8.48816  1.000 33.37637 ? 77  ASP D CG  1 
ATOM   6807 O  OD1 . ASP D 1 79  ? 3.24944   -29.01703 -7.58251  1.000 30.85459 ? 77  ASP D OD1 1 
ATOM   6808 O  OD2 . ASP D 1 79  ? 1.23902   -29.01721 -8.45041  1.000 35.17062 ? 77  ASP D OD2 1 
ATOM   6809 N  N   . GLU D 1 80  ? 4.88568   -31.26773 -12.06053 1.000 33.22501 ? 78  GLU D N   1 
ATOM   6810 C  CA  . GLU D 1 80  ? 5.29073   -32.31662 -12.98405 1.000 35.19560 ? 78  GLU D CA  1 
ATOM   6811 C  C   . GLU D 1 80  ? 6.78966   -32.31093 -13.24579 1.000 32.06776 ? 78  GLU D C   1 
ATOM   6812 O  O   . GLU D 1 80  ? 7.23749   -32.96188 -14.18449 1.000 32.71658 ? 78  GLU D O   1 
ATOM   6813 C  CB  . GLU D 1 80  ? 4.53619   -32.18838 -14.30930 1.000 33.03818 ? 78  GLU D CB  1 
ATOM   6814 C  CG  . GLU D 1 80  ? 3.01112   -32.22283 -14.14480 1.000 36.42773 ? 78  GLU D CG  1 
ATOM   6815 C  CD  . GLU D 1 80  ? 2.49106   -33.61849 -13.90820 1.000 46.79201 ? 78  GLU D CD  1 
ATOM   6816 O  OE1 . GLU D 1 80  ? 2.25284   -34.34312 -14.89790 1.000 50.69576 ? 78  GLU D OE1 1 
ATOM   6817 O  OE2 . GLU D 1 80  ? 2.32237   -33.99021 -12.73341 1.000 50.05028 ? 78  GLU D OE2 1 
ATOM   6818 N  N   . ASP D 1 81  ? 7.56790   -31.57821 -12.44671 1.000 33.25577 ? 79  ASP D N   1 
ATOM   6819 C  CA  . ASP D 1 81  ? 9.02482   -31.50908 -12.60321 1.000 35.37140 ? 79  ASP D CA  1 
ATOM   6820 C  C   . ASP D 1 81  ? 9.43607   -30.93592 -13.96162 1.000 34.63445 ? 79  ASP D C   1 
ATOM   6821 O  O   . ASP D 1 81  ? 10.48789  -31.28852 -14.49147 1.000 34.05444 ? 79  ASP D O   1 
ATOM   6822 C  CB  . ASP D 1 81  ? 9.69523   -32.87887 -12.42570 1.000 36.06130 ? 79  ASP D CB  1 
ATOM   6823 C  CG  . ASP D 1 81  ? 9.38970   -33.51982 -11.09586 1.000 38.16343 ? 79  ASP D CG  1 
ATOM   6824 O  OD1 . ASP D 1 81  ? 9.33291   -32.79735 -10.06522 1.000 35.65947 ? 79  ASP D OD1 1 
ATOM   6825 O  OD2 . ASP D 1 81  ? 9.26277   -34.76883 -11.08430 1.000 43.33415 ? 79  ASP D OD2 1 
ATOM   6826 N  N   . ARG D 1 82  ? 8.62362   -30.05683 -14.55105 1.000 31.42273 ? 80  ARG D N   1 
ATOM   6827 C  CA  . ARG D 1 82  ? 9.02305   -29.39842 -15.79737 1.000 33.59431 ? 80  ARG D CA  1 
ATOM   6828 C  C   . ARG D 1 82  ? 9.71296   -28.08918 -15.41680 1.000 29.76087 ? 80  ARG D C   1 
ATOM   6829 O  O   . ARG D 1 82  ? 9.14222   -27.01167 -15.47985 1.000 31.63333 ? 80  ARG D O   1 
ATOM   6830 C  CB  . ARG D 1 82  ? 7.81699   -29.21129 -16.71727 1.000 33.56066 ? 80  ARG D CB  1 
ATOM   6831 C  CG  . ARG D 1 82  ? 7.00194   -30.49297 -16.93783 1.000 34.99826 ? 80  ARG D CG  1 
ATOM   6832 C  CD  . ARG D 1 82  ? 5.83705   -30.33190 -17.93653 1.000 34.72912 ? 80  ARG D CD  1 
ATOM   6833 N  NE  . ARG D 1 82  ? 4.77510   -29.45109 -17.45511 1.000 35.16127 ? 80  ARG D NE  1 
ATOM   6834 C  CZ  . ARG D 1 82  ? 3.52390   -29.81150 -17.17163 1.000 37.57368 ? 80  ARG D CZ  1 
ATOM   6835 N  NH1 . ARG D 1 82  ? 3.13917   -31.07913 -17.19460 1.000 44.87608 ? 80  ARG D NH1 1 
ATOM   6836 N  NH2 . ARG D 1 82  ? 2.63466   -28.87488 -16.85101 1.000 39.15245 ? 80  ARG D NH2 1 
ATOM   6837 N  N   . TYR D 1 83  ? 10.96085  -28.22321 -14.95697 1.000 30.29139 ? 81  TYR D N   1 
ATOM   6838 C  CA  . TYR D 1 83  ? 11.73436  -27.10692 -14.41106 1.000 29.78511 ? 81  TYR D CA  1 
ATOM   6839 C  C   . TYR D 1 83  ? 11.91400  -26.01395 -15.44289 1.000 31.10155 ? 81  TYR D C   1 
ATOM   6840 O  O   . TYR D 1 83  ? 11.71113  -24.83577 -15.15592 1.000 29.87107 ? 81  TYR D O   1 
ATOM   6841 C  CB  . TYR D 1 83  ? 13.10909  -27.61111 -13.98407 1.000 31.02619 ? 81  TYR D CB  1 
ATOM   6842 C  CG  . TYR D 1 83  ? 13.07552  -28.75133 -12.98067 1.000 37.25427 ? 81  TYR D CG  1 
ATOM   6843 C  CD1 . TYR D 1 83  ? 11.91799  -29.09835 -12.31146 1.000 36.07674 ? 81  TYR D CD1 1 
ATOM   6844 C  CD2 . TYR D 1 83  ? 14.12531  -29.67560 -12.97353 1.000 42.25337 ? 81  TYR D CD2 1 
ATOM   6845 C  CE1 . TYR D 1 83  ? 11.89807  -30.20930 -11.45118 1.000 40.40787 ? 81  TYR D CE1 1 
ATOM   6846 C  CE2 . TYR D 1 83  ? 14.09830  -30.80377 -12.17161 1.000 42.12307 ? 81  TYR D CE2 1 
ATOM   6847 C  CZ  . TYR D 1 83  ? 12.99056  -31.06363 -11.40907 1.000 39.71249 ? 81  TYR D CZ  1 
ATOM   6848 O  OH  . TYR D 1 83  ? 12.98579  -32.19651 -10.60746 1.000 41.32392 ? 81  TYR D OH  1 
ATOM   6849 N  N   . HIS D 1 84  ? 12.33624  -26.39532 -16.65474 1.000 32.34152 ? 82  HIS D N   1 
ATOM   6850 C  CA  . HIS D 1 84  ? 12.60022  -25.39834 -17.68578 1.000 28.31260 ? 82  HIS D CA  1 
ATOM   6851 C  C   . HIS D 1 84  ? 11.35142  -24.61045 -18.00559 1.000 26.77661 ? 82  HIS D C   1 
ATOM   6852 O  O   . HIS D 1 84  ? 11.39471  -23.39084 -18.13979 1.000 28.65228 ? 82  HIS D O   1 
ATOM   6853 C  CB  . HIS D 1 84  ? 13.11192  -26.07485 -18.95807 1.000 29.73360 ? 82  HIS D CB  1 
ATOM   6854 C  CG  . HIS D 1 84  ? 14.35581  -26.88230 -18.75550 1.000 32.46714 ? 82  HIS D CG  1 
ATOM   6855 N  ND1 . HIS D 1 84  ? 14.33361  -28.17571 -18.27820 1.000 33.98189 ? 82  HIS D ND1 1 
ATOM   6856 C  CD2 . HIS D 1 84  ? 15.65599  -26.59114 -18.99546 1.000 34.46122 ? 82  HIS D CD2 1 
ATOM   6857 C  CE1 . HIS D 1 84  ? 15.57113  -28.63730 -18.21370 1.000 32.25467 ? 82  HIS D CE1 1 
ATOM   6858 N  NE2 . HIS D 1 84  ? 16.39049  -27.69499 -18.63929 1.000 36.55854 ? 82  HIS D NE2 1 
ATOM   6859 N  N   . GLN D 1 85  ? 10.22460  -25.29566 -18.15579 1.000 29.04326 ? 83  GLN D N   1 
ATOM   6860 C  CA  . GLN D 1 85  ? 9.00615   -24.57177 -18.46290 1.000 29.87675 ? 83  GLN D CA  1 
ATOM   6861 C  C   . GLN D 1 85  ? 8.59755   -23.65076 -17.31201 1.000 29.44980 ? 83  GLN D C   1 
ATOM   6862 O  O   . GLN D 1 85  ? 8.07091   -22.55716 -17.55782 1.000 31.72987 ? 83  GLN D O   1 
ATOM   6863 C  CB  . GLN D 1 85  ? 7.92500   -25.58253 -18.82821 1.000 27.74088 ? 83  GLN D CB  1 
ATOM   6864 C  CG  . GLN D 1 85  ? 8.28171   -26.28635 -20.15015 1.000 30.48405 ? 83  GLN D CG  1 
ATOM   6865 C  CD  . GLN D 1 85  ? 7.49009   -27.53695 -20.39236 1.000 34.26514 ? 83  GLN D CD  1 
ATOM   6866 O  OE1 . GLN D 1 85  ? 7.94575   -28.65226 -20.07290 1.000 28.95758 ? 83  GLN D OE1 1 
ATOM   6867 N  NE2 . GLN D 1 85  ? 6.28233   -27.37383 -20.94528 1.000 30.06908 ? 83  GLN D NE2 1 
ATOM   6868 N  N   . ALA D 1 86  ? 8.86329   -24.04787 -16.05666 1.000 27.42021 ? 84  ALA D N   1 
ATOM   6869 C  CA  . ALA D 1 86  ? 8.53192   -23.15839 -14.93345 1.000 31.09620 ? 84  ALA D CA  1 
ATOM   6870 C  C   . ALA D 1 86  ? 9.35740   -21.87239 -14.96263 1.000 28.52974 ? 84  ALA D C   1 
ATOM   6871 O  O   . ALA D 1 86  ? 8.85855   -20.79750 -14.59582 1.000 29.11514 ? 84  ALA D O   1 
ATOM   6872 C  CB  . ALA D 1 86  ? 8.75778   -23.87815 -13.61090 1.000 30.84707 ? 84  ALA D CB  1 
ATOM   6873 N  N   . VAL D 1 87  ? 10.64422  -21.98393 -15.32002 1.000 32.75185 ? 85  VAL D N   1 
ATOM   6874 C  CA  . VAL D 1 87  ? 11.51342  -20.81637 -15.42345 1.000 31.59987 ? 85  VAL D CA  1 
ATOM   6875 C  C   . VAL D 1 87  ? 10.84267  -19.72582 -16.25416 1.000 30.78644 ? 85  VAL D C   1 
ATOM   6876 O  O   . VAL D 1 87  ? 10.74707  -18.56903 -15.83516 1.000 31.06549 ? 85  VAL D O   1 
ATOM   6877 C  CB  . VAL D 1 87  ? 12.87568  -21.20803 -16.02449 1.000 32.33636 ? 85  VAL D CB  1 
ATOM   6878 C  CG1 . VAL D 1 87  ? 13.70935  -19.94035 -16.31185 1.000 34.77774 ? 85  VAL D CG1 1 
ATOM   6879 C  CG2 . VAL D 1 87  ? 13.61513  -22.12609 -15.09977 1.000 36.31691 ? 85  VAL D CG2 1 
ATOM   6880 N  N   . ARG D 1 88  ? 10.38094  -20.09225 -17.45079 1.000 31.69120 ? 86  ARG D N   1 
ATOM   6881 C  CA  . ARG D 1 88  ? 9.78135   -19.13388 -18.37467 1.000 31.20352 ? 86  ARG D CA  1 
ATOM   6882 C  C   . ARG D 1 88  ? 8.56975   -18.43844 -17.76777 1.000 33.57468 ? 86  ARG D C   1 
ATOM   6883 O  O   . ARG D 1 88  ? 8.29286   -17.28254 -18.08573 1.000 28.12128 ? 86  ARG D O   1 
ATOM   6884 C  CB  . ARG D 1 88  ? 9.37773   -19.85140 -19.66454 1.000 30.58434 ? 86  ARG D CB  1 
ATOM   6885 C  CG  . ARG D 1 88  ? 10.52725  -20.46524 -20.44309 1.000 29.50468 ? 86  ARG D CG  1 
ATOM   6886 C  CD  . ARG D 1 88  ? 10.13725  -20.70416 -21.88632 1.000 28.00311 ? 86  ARG D CD  1 
ATOM   6887 N  NE  . ARG D 1 88  ? 11.14409  -21.51612 -22.57873 1.000 27.14430 ? 86  ARG D NE  1 
ATOM   6888 C  CZ  . ARG D 1 88  ? 11.13665  -22.84197 -22.65725 1.000 29.73594 ? 86  ARG D CZ  1 
ATOM   6889 N  NH1 . ARG D 1 88  ? 10.17075  -23.56660 -22.10118 1.000 26.11798 ? 86  ARG D NH1 1 
ATOM   6890 N  NH2 . ARG D 1 88  ? 12.13581  -23.46158 -23.29896 1.000 27.97672 ? 86  ARG D NH2 1 
ATOM   6891 N  N   . MET D 1 89  ? 7.82333   -19.13053 -16.91856 1.000 29.79829 ? 87  MET D N   1 
ATOM   6892 C  CA  . MET D 1 89  ? 6.64739   -18.51053 -16.32203 1.000 29.74146 ? 87  MET D CA  1 
ATOM   6893 C  C   . MET D 1 89  ? 7.06916   -17.42164 -15.35493 1.000 33.53607 ? 87  MET D C   1 
ATOM   6894 O  O   . MET D 1 89  ? 6.50007   -16.32053 -15.35154 1.000 29.65083 ? 87  MET D O   1 
ATOM   6895 C  CB  . MET D 1 89  ? 5.83723   -19.54925 -15.56887 1.000 32.84310 ? 87  MET D CB  1 
ATOM   6896 C  CG  . MET D 1 89  ? 4.87355   -20.39462 -16.35344 1.000 36.27744 ? 87  MET D CG  1 
ATOM   6897 S  SD  . MET D 1 89  ? 4.10954   -19.74642 -17.82626 1.000 48.99295 ? 87  MET D SD  1 
ATOM   6898 C  CE  . MET D 1 89  ? 5.30365   -20.24626 -19.04514 1.000 36.67786 ? 87  MET D CE  1 
ATOM   6899 N  N   . PHE D 1 90  ? 8.05395   -17.73370 -14.50333 1.000 30.03019 ? 88  PHE D N   1 
ATOM   6900 C  CA  . PHE D 1 90  ? 8.58590   -16.75778 -13.55432 1.000 34.29229 ? 88  PHE D CA  1 
ATOM   6901 C  C   . PHE D 1 90  ? 9.20501   -15.54462 -14.25465 1.000 31.61220 ? 88  PHE D C   1 
ATOM   6902 O  O   . PHE D 1 90  ? 8.95055   -14.40426 -13.85294 1.000 34.38229 ? 88  PHE D O   1 
ATOM   6903 C  CB  . PHE D 1 90  ? 9.59901   -17.43212 -12.62940 1.000 33.02231 ? 88  PHE D CB  1 
ATOM   6904 C  CG  . PHE D 1 90  ? 8.99261   -18.39937 -11.65617 1.000 31.17042 ? 88  PHE D CG  1 
ATOM   6905 C  CD1 . PHE D 1 90  ? 7.99693   -17.97981 -10.76839 1.000 35.35336 ? 88  PHE D CD1 1 
ATOM   6906 C  CD2 . PHE D 1 90  ? 9.36778   -19.74494 -11.65337 1.000 32.53381 ? 88  PHE D CD2 1 
ATOM   6907 C  CE1 . PHE D 1 90  ? 7.42493   -18.85766 -9.85783  1.000 33.79732 ? 88  PHE D CE1 1 
ATOM   6908 C  CE2 . PHE D 1 90  ? 8.78177   -20.65786 -10.74099 1.000 31.53068 ? 88  PHE D CE2 1 
ATOM   6909 C  CZ  . PHE D 1 90  ? 7.80848   -20.19409 -9.83909  1.000 32.84093 ? 88  PHE D CZ  1 
ATOM   6910 N  N   . ASP D 1 91  ? 10.01039  -15.75589 -15.30550 1.000 31.23508 ? 89  ASP D N   1 
ATOM   6911 C  CA  . ASP D 1 91  ? 10.61549  -14.61368 -15.99514 1.000 29.99128 ? 89  ASP D CA  1 
ATOM   6912 C  C   . ASP D 1 91  ? 9.55494   -13.70960 -16.61558 1.000 33.36379 ? 89  ASP D C   1 
ATOM   6913 O  O   . ASP D 1 91  ? 9.70246   -12.47928 -16.64129 1.000 31.88138 ? 89  ASP D O   1 
ATOM   6914 C  CB  . ASP D 1 91  ? 11.57891  -15.08423 -17.08166 1.000 31.89857 ? 89  ASP D CB  1 
ATOM   6915 C  CG  . ASP D 1 91  ? 12.88478  -15.62977 -16.52367 1.000 32.04693 ? 89  ASP D CG  1 
ATOM   6916 O  OD1 . ASP D 1 91  ? 13.26725  -15.33207 -15.36146 1.000 33.54042 ? 89  ASP D OD1 1 
ATOM   6917 O  OD2 . ASP D 1 91  ? 13.51375  -16.39480 -17.26202 1.000 29.50516 ? 89  ASP D OD2 1 
ATOM   6918 N  N   . ARG D 1 92  ? 8.50340   -14.30669 -17.16291 1.000 30.49658 ? 90  ARG D N   1 
ATOM   6919 C  CA  . ARG D 1 92  ? 7.40362   -13.53492 -17.72934 1.000 31.69456 ? 90  ARG D CA  1 
ATOM   6920 C  C   . ARG D 1 92  ? 6.67097   -12.73214 -16.65728 1.000 33.27049 ? 90  ARG D C   1 
ATOM   6921 O  O   . ARG D 1 92  ? 6.34855   -11.54543 -16.85518 1.000 31.35856 ? 90  ARG D O   1 
ATOM   6922 C  CB  . ARG D 1 92  ? 6.45494   -14.50589 -18.43478 1.000 30.92428 ? 90  ARG D CB  1 
ATOM   6923 C  CG  . ARG D 1 92  ? 5.49942   -13.88623 -19.41795 1.000 33.12980 ? 90  ARG D CG  1 
ATOM   6924 C  CD  . ARG D 1 92  ? 4.49762   -14.94753 -19.83201 1.000 32.40628 ? 90  ARG D CD  1 
ATOM   6925 N  NE  . ARG D 1 92  ? 5.03378   -15.86780 -20.82692 1.000 32.53652 ? 90  ARG D NE  1 
ATOM   6926 C  CZ  . ARG D 1 92  ? 4.27678   -16.58743 -21.64373 1.000 32.77226 ? 90  ARG D CZ  1 
ATOM   6927 N  NH1 . ARG D 1 92  ? 2.95367   -16.48759 -21.62305 1.000 29.34227 ? 90  ARG D NH1 1 
ATOM   6928 N  NH2 . ARG D 1 92  ? 4.85803   -17.46586 -22.46573 1.000 32.82873 ? 90  ARG D NH2 1 
ATOM   6929 N  N   . ALA D 1 93  ? 6.38129   -13.36619 -15.51117 1.000 28.66807 ? 91  ALA D N   1 
ATOM   6930 C  CA  . ALA D 1 93  ? 5.75618   -12.63548 -14.42316 1.000 27.90186 ? 91  ALA D CA  1 
ATOM   6931 C  C   . ALA D 1 93  ? 6.61593   -11.46321 -13.99792 1.000 29.87402 ? 91  ALA D C   1 
ATOM   6932 O  O   . ALA D 1 93  ? 6.09235   -10.39853 -13.65999 1.000 31.34227 ? 91  ALA D O   1 
ATOM   6933 C  CB  . ALA D 1 93  ? 5.49881   -13.55321 -13.23193 1.000 32.96210 ? 91  ALA D CB  1 
ATOM   6934 N  N   . THR D 1 94  ? 7.93514   -11.65248 -13.97096 1.000 29.55162 ? 92  THR D N   1 
ATOM   6935 C  CA  . THR D 1 94  ? 8.82635   -10.56466 -13.60444 1.000 28.32335 ? 92  THR D CA  1 
ATOM   6936 C  C   . THR D 1 94  ? 8.69356   -9.40258  -14.59029 1.000 31.35051 ? 92  THR D C   1 
ATOM   6937 O  O   . THR D 1 94  ? 8.55268   -8.24798  -14.18421 1.000 31.52635 ? 92  THR D O   1 
ATOM   6938 C  CB  . THR D 1 94  ? 10.26695  -11.08877 -13.52674 1.000 31.70281 ? 92  THR D CB  1 
ATOM   6939 O  OG1 . THR D 1 94  ? 10.35973  -12.05856 -12.48263 1.000 31.44910 ? 92  THR D OG1 1 
ATOM   6940 C  CG2 . THR D 1 94  ? 11.25235  -9.97056  -13.22919 1.000 30.99504 ? 92  THR D CG2 1 
ATOM   6941 N  N   . GLY D 1 95  ? 8.67799   -9.69528  -15.89576 1.000 31.86134 ? 93  GLY D N   1 
ATOM   6942 C  CA  . GLY D 1 95  ? 8.49338   -8.62744  -16.87015 1.000 27.20446 ? 93  GLY D CA  1 
ATOM   6943 C  C   . GLY D 1 95  ? 7.15643   -7.91724  -16.72513 1.000 30.52828 ? 93  GLY D C   1 
ATOM   6944 O  O   . GLY D 1 95  ? 7.07410   -6.69208  -16.87222 1.000 30.01617 ? 93  GLY D O   1 
ATOM   6945 N  N   . LEU D 1 96  ? 6.09359   -8.67380  -16.45773 1.000 27.88095 ? 94  LEU D N   1 
ATOM   6946 C  CA  . LEU D 1 96  ? 4.78155   -8.09329  -16.19435 1.000 29.15791 ? 94  LEU D CA  1 
ATOM   6947 C  C   . LEU D 1 96  ? 4.78768   -7.27617  -14.90698 1.000 31.66312 ? 94  LEU D C   1 
ATOM   6948 O  O   . LEU D 1 96  ? 4.14805   -6.21010  -14.82984 1.000 27.70856 ? 94  LEU D O   1 
ATOM   6949 C  CB  . LEU D 1 96  ? 3.73628   -9.20061  -16.12233 1.000 27.57959 ? 94  LEU D CB  1 
ATOM   6950 C  CG  . LEU D 1 96  ? 3.41460   -9.82491  -17.47837 1.000 27.86732 ? 94  LEU D CG  1 
ATOM   6951 C  CD1 . LEU D 1 96  ? 2.87476   -11.25950 -17.28682 1.000 28.39709 ? 94  LEU D CD1 1 
ATOM   6952 C  CD2 . LEU D 1 96  ? 2.38671   -8.96343  -18.17367 1.000 25.94304 ? 94  LEU D CD2 1 
ATOM   6953 N  N   . SER D 1 97  ? 5.52577   -7.74353  -13.89300 1.000 32.47359 ? 95  SER D N   1 
ATOM   6954 C  CA  . SER D 1 97  ? 5.65129   -6.95993  -12.66926 1.000 30.24234 ? 95  SER D CA  1 
ATOM   6955 C  C   . SER D 1 97  ? 6.36471   -5.63223  -12.93570 1.000 31.04660 ? 95  SER D C   1 
ATOM   6956 O  O   . SER D 1 97  ? 5.97025   -4.59197  -12.39826 1.000 30.17042 ? 95  SER D O   1 
ATOM   6957 C  CB  . SER D 1 97  ? 6.39040   -7.75830  -11.59139 1.000 34.36923 ? 95  SER D CB  1 
ATOM   6958 O  OG  . SER D 1 97  ? 6.65945   -6.95360  -10.43971 1.000 32.12745 ? 95  SER D OG  1 
ATOM   6959 N  N   . GLU D 1 98  ? 7.41103   -5.65095  -13.76729 1.000 30.22769 ? 96  GLU D N   1 
ATOM   6960 C  CA  . GLU D 1 98  ? 8.12569   -4.42239  -14.07276 1.000 33.58172 ? 96  GLU D CA  1 
ATOM   6961 C  C   . GLU D 1 98  ? 7.22855   -3.42317  -14.78308 1.000 31.05761 ? 96  GLU D C   1 
ATOM   6962 O  O   . GLU D 1 98  ? 7.40320   -2.20814  -14.61330 1.000 29.75459 ? 96  GLU D O   1 
ATOM   6963 C  CB  . GLU D 1 98  ? 9.37628   -4.75033  -14.88155 1.000 35.39216 ? 96  GLU D CB  1 
ATOM   6964 C  CG  . GLU D 1 98  ? 10.42667  -5.39617  -13.98721 1.000 33.80594 ? 96  GLU D CG  1 
ATOM   6965 C  CD  . GLU D 1 98  ? 10.99239  -4.39301  -12.97359 1.000 37.01110 ? 96  GLU D CD  1 
ATOM   6966 O  OE1 . GLU D 1 98  ? 11.55186  -3.39004  -13.40324 1.000 35.59518 ? 96  GLU D OE1 1 
ATOM   6967 O  OE2 . GLU D 1 98  ? 10.86759  -4.59982  -11.75169 1.000 34.74694 ? 96  GLU D OE2 1 
ATOM   6968 N  N   . VAL D 1 99  ? 6.22331   -3.90449  -15.52646 1.000 30.63876 ? 97  VAL D N   1 
ATOM   6969 C  CA  . VAL D 1 99  ? 5.21930   -2.98023  -16.06688 1.000 28.31653 ? 97  VAL D CA  1 
ATOM   6970 C  C   . VAL D 1 99  ? 4.45120   -2.28451  -14.93322 1.000 29.55233 ? 97  VAL D C   1 
ATOM   6971 O  O   . VAL D 1 99  ? 4.17044   -1.07602  -15.01421 1.000 31.29782 ? 97  VAL D O   1 
ATOM   6972 C  CB  . VAL D 1 99  ? 4.27224   -3.70961  -17.04459 1.000 28.44983 ? 97  VAL D CB  1 
ATOM   6973 C  CG1 . VAL D 1 99  ? 3.03492   -2.84937  -17.33925 1.000 31.50929 ? 97  VAL D CG1 1 
ATOM   6974 C  CG2 . VAL D 1 99  ? 5.00700   -4.03289  -18.37843 1.000 23.84802 ? 97  VAL D CG2 1 
ATOM   6975 N  N   . THR D 1 100 ? 4.11052   -3.00598  -13.85741 1.000 27.89869 ? 98  THR D N   1 
ATOM   6976 C  CA  . THR D 1 100 ? 3.39068   -2.32742  -12.76280 1.000 30.98068 ? 98  THR D CA  1 
ATOM   6977 C  C   . THR D 1 100 ? 4.27249   -1.27758  -12.10340 1.000 29.25407 ? 98  THR D C   1 
ATOM   6978 O  O   . THR D 1 100 ? 3.77588   -0.22556  -11.69053 1.000 26.41911 ? 98  THR D O   1 
ATOM   6979 C  CB  . THR D 1 100 ? 2.84623   -3.29021  -11.68379 1.000 30.57460 ? 98  THR D CB  1 
ATOM   6980 O  OG1 . THR D 1 100 ? 3.91247   -3.89402  -10.93150 1.000 34.64002 ? 98  THR D OG1 1 
ATOM   6981 C  CG2 . THR D 1 100 ? 1.92626   -4.40293  -12.26400 1.000 27.06379 ? 98  THR D CG2 1 
ATOM   6982 N  N   . VAL D 1 101 ? 5.57789   -1.55077  -11.97869 1.000 30.12220 ? 99  VAL D N   1 
ATOM   6983 C  CA  . VAL D 1 101 ? 6.49574   -0.53794  -11.44928 1.000 29.47227 ? 99  VAL D CA  1 
ATOM   6984 C  C   . VAL D 1 101 ? 6.45367   0.72103   -12.30776 1.000 29.73350 ? 99  VAL D C   1 
ATOM   6985 O  O   . VAL D 1 101 ? 6.40192   1.83870   -11.78723 1.000 30.02237 ? 99  VAL D O   1 
ATOM   6986 C  CB  . VAL D 1 101 ? 7.93005   -1.09555  -11.34860 1.000 30.15892 ? 99  VAL D CB  1 
ATOM   6987 C  CG1 . VAL D 1 101 ? 8.90654   -0.00710  -10.84332 1.000 31.73100 ? 99  VAL D CG1 1 
ATOM   6988 C  CG2 . VAL D 1 101 ? 7.96004   -2.27791  -10.45878 1.000 30.55855 ? 99  VAL D CG2 1 
ATOM   6989 N  N   . GLN D 1 102 ? 6.50648   0.56342   -13.63859 1.000 29.49852 ? 100 GLN D N   1 
ATOM   6990 C  CA  . GLN D 1 102 ? 6.45062   1.73587   -14.51795 1.000 29.72777 ? 100 GLN D CA  1 
ATOM   6991 C  C   . GLN D 1 102 ? 5.15748   2.50866   -14.30807 1.000 32.13822 ? 100 GLN D C   1 
ATOM   6992 O  O   . GLN D 1 102 ? 5.14597   3.74330   -14.33841 1.000 32.35318 ? 100 GLN D O   1 
ATOM   6993 C  CB  . GLN D 1 102 ? 6.48809   1.32380   -15.99060 1.000 32.70984 ? 100 GLN D CB  1 
ATOM   6994 C  CG  . GLN D 1 102 ? 7.77268   1.05306   -16.68028 1.000 37.53719 ? 100 GLN D CG  1 
ATOM   6995 C  CD  . GLN D 1 102 ? 7.51323   0.79515   -18.20394 1.000 40.46062 ? 100 GLN D CD  1 
ATOM   6996 O  OE1 . GLN D 1 102 ? 7.12313   -0.31880  -18.57657 1.000 34.51604 ? 100 GLN D OE1 1 
ATOM   6997 N  NE2 . GLN D 1 102 ? 7.82255   1.77708   -19.07017 1.000 33.71098 ? 100 GLN D NE2 1 
ATOM   6998 N  N   . ALA D 1 103 ? 4.03919   1.78844   -14.16299 1.000 31.47635 ? 101 ALA D N   1 
ATOM   6999 C  CA  . ALA D 1 103 ? 2.74747   2.45494   -14.11026 1.000 28.15342 ? 101 ALA D CA  1 
ATOM   7000 C  C   . ALA D 1 103 ? 2.59613   3.26386   -12.82849 1.000 28.99751 ? 101 ALA D C   1 
ATOM   7001 O  O   . ALA D 1 103 ? 2.03774   4.36885   -12.84932 1.000 29.95594 ? 101 ALA D O   1 
ATOM   7002 C  CB  . ALA D 1 103 ? 1.62554   1.42686   -14.24468 1.000 25.91185 ? 101 ALA D CB  1 
ATOM   7003 N  N   . VAL D 1 104 ? 3.09223   2.75382   -11.70086 1.000 27.09328 ? 102 VAL D N   1 
ATOM   7004 C  CA  . VAL D 1 104 ? 2.97797   3.58792   -10.50241 1.000 28.14088 ? 102 VAL D CA  1 
ATOM   7005 C  C   . VAL D 1 104 ? 3.98726   4.73699   -10.56719 1.000 31.57011 ? 102 VAL D C   1 
ATOM   7006 O  O   . VAL D 1 104 ? 3.69289   5.85020   -10.11943 1.000 31.27518 ? 102 VAL D O   1 
ATOM   7007 C  CB  . VAL D 1 104 ? 3.12141   2.73735   -9.21619  1.000 27.52427 ? 102 VAL D CB  1 
ATOM   7008 C  CG1 . VAL D 1 104 ? 4.58265   2.45013   -8.90272  1.000 30.90705 ? 102 VAL D CG1 1 
ATOM   7009 C  CG2 . VAL D 1 104 ? 2.47166   3.45720   -8.03688  1.000 32.05305 ? 102 VAL D CG2 1 
ATOM   7010 N  N   . ARG D 1 105 ? 5.15022   4.53237   -11.20252 1.000 30.23669 ? 103 ARG D N   1 
ATOM   7011 C  CA  . ARG D 1 105 ? 6.09480   5.63698   -11.29614 1.000 32.77259 ? 103 ARG D CA  1 
ATOM   7012 C  C   . ARG D 1 105 ? 5.60442   6.72150   -12.25659 1.000 33.75161 ? 103 ARG D C   1 
ATOM   7013 O  O   . ARG D 1 105 ? 6.02267   7.87729   -12.14376 1.000 32.29424 ? 103 ARG D O   1 
ATOM   7014 C  CB  . ARG D 1 105 ? 7.46484   5.12538   -11.71188 1.000 33.35056 ? 103 ARG D CB  1 
ATOM   7015 C  CG  . ARG D 1 105 ? 8.08735   4.21592   -10.67818 1.000 33.46177 ? 103 ARG D CG  1 
ATOM   7016 C  CD  . ARG D 1 105 ? 9.53179   3.95992   -11.01623 1.000 35.00317 ? 103 ARG D CD  1 
ATOM   7017 N  NE  . ARG D 1 105 ? 10.31392  5.18553   -10.86595 1.000 33.05329 ? 103 ARG D NE  1 
ATOM   7018 C  CZ  . ARG D 1 105 ? 11.62409  5.26616   -11.07076 1.000 36.39010 ? 103 ARG D CZ  1 
ATOM   7019 N  NH1 . ARG D 1 105 ? 12.32551  4.22051   -11.47359 1.000 38.35406 ? 103 ARG D NH1 1 
ATOM   7020 N  NH2 . ARG D 1 105 ? 12.24563  6.42483   -10.87010 1.000 34.96085 ? 103 ARG D NH2 1 
ATOM   7021 N  N   . LEU D 1 106 ? 4.69514   6.37759   -13.16869 1.000 32.70375 ? 104 LEU D N   1 
ATOM   7022 C  CA  . LEU D 1 106 ? 4.00600   7.39767   -13.94542 1.000 30.67818 ? 104 LEU D CA  1 
ATOM   7023 C  C   . LEU D 1 106 ? 3.26971   8.37932   -13.03425 1.000 33.37967 ? 104 LEU D C   1 
ATOM   7024 O  O   . LEU D 1 106 ? 3.26283   9.59045   -13.28354 1.000 31.58224 ? 104 LEU D O   1 
ATOM   7025 C  CB  . LEU D 1 106 ? 3.02848   6.72592   -14.89938 1.000 32.93977 ? 104 LEU D CB  1 
ATOM   7026 C  CG  . LEU D 1 106 ? 3.52677   6.18933   -16.24967 1.000 29.39702 ? 104 LEU D CG  1 
ATOM   7027 C  CD1 . LEU D 1 106 ? 2.29866   5.70765   -17.00853 1.000 28.09563 ? 104 LEU D CD1 1 
ATOM   7028 C  CD2 . LEU D 1 106 ? 4.28150   7.23464   -17.05186 1.000 31.39915 ? 104 LEU D CD2 1 
ATOM   7029 N  N   . LEU D 1 107 ? 2.61868   7.87378   -11.98563 1.000 32.92535 ? 105 LEU D N   1 
ATOM   7030 C  CA  . LEU D 1 107 ? 1.95002   8.76375   -11.04155 1.000 33.55396 ? 105 LEU D CA  1 
ATOM   7031 C  C   . LEU D 1 107 ? 2.96700   9.58229   -10.25915 1.000 30.20124 ? 105 LEU D C   1 
ATOM   7032 O  O   . LEU D 1 107 ? 2.82111   10.80548  -10.11800 1.000 34.79420 ? 105 LEU D O   1 
ATOM   7033 C  CB  . LEU D 1 107 ? 1.05698   7.94205   -10.09323 1.000 30.47401 ? 105 LEU D CB  1 
ATOM   7034 C  CG  . LEU D 1 107 ? -0.19657  7.29869   -10.70346 1.000 32.97080 ? 105 LEU D CG  1 
ATOM   7035 C  CD1 . LEU D 1 107 ? -1.09190  6.64913   -9.60951  1.000 30.71966 ? 105 LEU D CD1 1 
ATOM   7036 C  CD2 . LEU D 1 107 ? -1.00733  8.28582   -11.53177 1.000 29.74864 ? 105 LEU D CD2 1 
ATOM   7037 N  N   . THR D 1 108 ? 4.00957   8.92289   -9.73759  1.000 31.41238 ? 106 THR D N   1 
ATOM   7038 C  CA  . THR D 1 108 ? 5.06055   9.64118   -9.01643  1.000 30.70387 ? 106 THR D CA  1 
ATOM   7039 C  C   . THR D 1 108 ? 5.56795   10.80819  -9.83342  1.000 33.43478 ? 106 THR D C   1 
ATOM   7040 O  O   . THR D 1 108 ? 5.73719   11.92121  -9.31902  1.000 32.79689 ? 106 THR D O   1 
ATOM   7041 C  CB  . THR D 1 108 ? 6.22993   8.71019   -8.69989  1.000 34.30139 ? 106 THR D CB  1 
ATOM   7042 O  OG1 . THR D 1 108 ? 5.74603   7.59334   -7.96975  1.000 36.76830 ? 106 THR D OG1 1 
ATOM   7043 C  CG2 . THR D 1 108 ? 7.29295   9.43194   -7.86346  1.000 30.94451 ? 106 THR D CG2 1 
ATOM   7044 N  N   . ASP D 1 109 ? 5.81117   10.55943  -11.12289 1.000 32.89108 ? 107 ASP D N   1 
ATOM   7045 C  CA  . ASP D 1 109 ? 6.49504   11.52393  -11.96204 1.000 32.31259 ? 107 ASP D CA  1 
ATOM   7046 C  C   . ASP D 1 109 ? 5.54999   12.57827  -12.51905 1.000 34.20579 ? 107 ASP D C   1 
ATOM   7047 O  O   . ASP D 1 109 ? 5.98491   13.70564  -12.77613 1.000 32.59957 ? 107 ASP D O   1 
ATOM   7048 C  CB  . ASP D 1 109 ? 7.20567   10.82969  -13.13776 1.000 31.77849 ? 107 ASP D CB  1 
ATOM   7049 C  CG  . ASP D 1 109 ? 8.46423   10.06853  -12.72419 1.000 38.36073 ? 107 ASP D CG  1 
ATOM   7050 O  OD1 . ASP D 1 109 ? 8.95173   10.25098  -11.58291 1.000 36.54241 ? 107 ASP D OD1 1 
ATOM   7051 O  OD2 . ASP D 1 109 ? 8.94365   9.24838   -13.55073 1.000 37.81987 ? 107 ASP D OD2 1 
ATOM   7052 N  N   . HIS D 1 110 ? 4.27611   12.24865  -12.74043 1.000 30.43811 ? 108 HIS D N   1 
ATOM   7053 C  CA  . HIS D 1 110 ? 3.41860   13.14530  -13.52679 1.000 35.65965 ? 108 HIS D CA  1 
ATOM   7054 C  C   . HIS D 1 110 ? 2.07902   13.50362  -12.86909 1.000 32.30249 ? 108 HIS D C   1 
ATOM   7055 O  O   . HIS D 1 110 ? 1.42678   14.43774  -13.33844 1.000 31.64105 ? 108 HIS D O   1 
ATOM   7056 C  CB  . HIS D 1 110 ? 3.14387   12.51042  -14.90149 1.000 32.58071 ? 108 HIS D CB  1 
ATOM   7057 C  CG  . HIS D 1 110 ? 4.37757   12.21862  -15.70165 1.000 32.92007 ? 108 HIS D CG  1 
ATOM   7058 N  ND1 . HIS D 1 110 ? 5.33082   13.17310  -16.00780 1.000 36.62593 ? 108 HIS D ND1 1 
ATOM   7059 C  CD2 . HIS D 1 110 ? 4.88665   11.03116  -16.12815 1.000 33.14026 ? 108 HIS D CD2 1 
ATOM   7060 C  CE1 . HIS D 1 110 ? 6.32092   12.60019  -16.67466 1.000 34.02080 ? 108 HIS D CE1 1 
ATOM   7061 N  NE2 . HIS D 1 110 ? 6.08458   11.29856  -16.74586 1.000 32.09194 ? 108 HIS D NE2 1 
ATOM   7062 N  N   . LEU D 1 111 ? 1.62505   12.78731  -11.84183 1.000 32.47973 ? 109 LEU D N   1 
ATOM   7063 C  CA  . LEU D 1 111 ? 0.35134   13.14805  -11.20385 1.000 31.44517 ? 109 LEU D CA  1 
ATOM   7064 C  C   . LEU D 1 111 ? 0.57437   14.29848  -10.23318 1.000 31.18894 ? 109 LEU D C   1 
ATOM   7065 O  O   . LEU D 1 111 ? 1.31024   14.12681  -9.25697  1.000 31.75873 ? 109 LEU D O   1 
ATOM   7066 C  CB  . LEU D 1 111 ? -0.24962  11.95342  -10.45284 1.000 31.36969 ? 109 LEU D CB  1 
ATOM   7067 C  CG  . LEU D 1 111 ? -1.61209  12.16870  -9.75839  1.000 29.64884 ? 109 LEU D CG  1 
ATOM   7068 C  CD1 . LEU D 1 111 ? -2.76981  12.24904  -10.75140 1.000 28.17929 ? 109 LEU D CD1 1 
ATOM   7069 C  CD2 . LEU D 1 111 ? -1.88459  11.03949  -8.75095  1.000 30.50676 ? 109 LEU D CD2 1 
ATOM   7070 N  N   . PRO D 1 112 ? -0.03433  15.47036  -10.45035 1.000 30.79089 ? 110 PRO D N   1 
ATOM   7071 C  CA  . PRO D 1 112 ? 0.16291   16.58593  -9.51089  1.000 31.06179 ? 110 PRO D CA  1 
ATOM   7072 C  C   . PRO D 1 112 ? -0.46877  16.24857  -8.16685  1.000 32.10559 ? 110 PRO D C   1 
ATOM   7073 O  O   . PRO D 1 112 ? -1.61512  15.80066  -8.10533  1.000 30.50067 ? 110 PRO D O   1 
ATOM   7074 C  CB  . PRO D 1 112 ? -0.54709  17.77111  -10.19214 1.000 32.49411 ? 110 PRO D CB  1 
ATOM   7075 C  CG  . PRO D 1 112 ? -0.80664  17.29732  -11.66676 1.000 34.41381 ? 110 PRO D CG  1 
ATOM   7076 C  CD  . PRO D 1 112 ? -1.00607  15.80139  -11.50640 1.000 28.32396 ? 110 PRO D CD  1 
ATOM   7077 N  N   . GLN D 1 113 ? 0.29844   16.43556  -7.09289  1.000 32.87181 ? 111 GLN D N   1 
ATOM   7078 C  CA  . GLN D 1 113 ? -0.26260  16.22278  -5.76027  1.000 31.94828 ? 111 GLN D CA  1 
ATOM   7079 C  C   . GLN D 1 113 ? -1.53965  17.03649  -5.57287  1.000 34.35796 ? 111 GLN D C   1 
ATOM   7080 O  O   . GLN D 1 113 ? -2.51173  16.55806  -4.97400  1.000 35.96074 ? 111 GLN D O   1 
ATOM   7081 C  CB  . GLN D 1 113 ? 0.75075   16.59343  -4.67538  1.000 33.72386 ? 111 GLN D CB  1 
ATOM   7082 C  CG  . GLN D 1 113 ? 0.12470   16.56734  -3.25851  1.000 35.29271 ? 111 GLN D CG  1 
ATOM   7083 C  CD  . GLN D 1 113 ? 1.06168   17.05160  -2.16261  1.000 34.84912 ? 111 GLN D CD  1 
ATOM   7084 O  OE1 . GLN D 1 113 ? 1.89790   17.93482  -2.38669  1.000 36.10275 ? 111 GLN D OE1 1 
ATOM   7085 N  NE2 . GLN D 1 113 ? 0.92261   16.47994  -0.96477  1.000 31.31502 ? 111 GLN D NE2 1 
ATOM   7086 N  N   . HIS D 1 114 ? -1.56918  18.27007  -6.09001  1.000 33.22935 ? 112 HIS D N   1 
ATOM   7087 C  CA  . HIS D 1 114 ? -2.74613  19.09179  -5.84121  1.000 30.88489 ? 112 HIS D CA  1 
ATOM   7088 C  C   . HIS D 1 114 ? -3.96562  18.48354  -6.53380  1.000 34.06129 ? 112 HIS D C   1 
ATOM   7089 O  O   . HIS D 1 114 ? -5.07328  18.54060  -5.99378  1.000 33.50923 ? 112 HIS D O   1 
ATOM   7090 C  CB  . HIS D 1 114 ? -2.54114  20.52105  -6.33816  1.000 35.25752 ? 112 HIS D CB  1 
ATOM   7091 C  CG  . HIS D 1 114 ? -3.67165  21.44187  -5.99442  1.000 34.06299 ? 112 HIS D CG  1 
ATOM   7092 N  ND1 . HIS D 1 114 ? -4.75531  21.64238  -6.82387  1.000 36.72609 ? 112 HIS D ND1 1 
ATOM   7093 C  CD2 . HIS D 1 114 ? -3.81639  22.31594  -4.96661  1.000 34.59900 ? 112 HIS D CD2 1 
ATOM   7094 C  CE1 . HIS D 1 114 ? -5.56386  22.53595  -6.27630  1.000 39.86172 ? 112 HIS D CE1 1 
ATOM   7095 N  NE2 . HIS D 1 114 ? -5.00229  22.98225  -5.16464  1.000 36.06154 ? 112 HIS D NE2 1 
ATOM   7096 N  N   . SER D 1 115 ? -3.78086  17.87404  -7.71951  1.000 32.69452 ? 113 SER D N   1 
ATOM   7097 C  CA  . SER D 1 115 ? -4.87767  17.15385  -8.37646  1.000 30.10914 ? 113 SER D CA  1 
ATOM   7098 C  C   . SER D 1 115 ? -5.33898  15.96889  -7.54342  1.000 34.23042 ? 113 SER D C   1 
ATOM   7099 O  O   . SER D 1 115 ? -6.54159  15.67833  -7.45227  1.000 34.54366 ? 113 SER D O   1 
ATOM   7100 C  CB  . SER D 1 115 ? -4.44387  16.63941  -9.75452  1.000 31.25396 ? 113 SER D CB  1 
ATOM   7101 O  OG  . SER D 1 115 ? -4.22858  17.67538  -10.69714 1.000 27.99708 ? 113 SER D OG  1 
ATOM   7102 N  N   . LEU D 1 116 ? -4.38630  15.19763  -7.03097  1.000 34.70835 ? 114 LEU D N   1 
ATOM   7103 C  CA  . LEU D 1 116 ? -4.73412  14.00820  -6.26842  1.000 34.56890 ? 114 LEU D CA  1 
ATOM   7104 C  C   . LEU D 1 116 ? -5.59372  14.38610  -5.06607  1.000 34.44766 ? 114 LEU D C   1 
ATOM   7105 O  O   . LEU D 1 116 ? -6.62466  13.75540  -4.78466  1.000 35.47496 ? 114 LEU D O   1 
ATOM   7106 C  CB  . LEU D 1 116 ? -3.44978  13.31592  -5.82778  1.000 32.15715 ? 114 LEU D CB  1 
ATOM   7107 C  CG  . LEU D 1 116 ? -3.45864  11.99085  -5.07423  1.000 34.82442 ? 114 LEU D CG  1 
ATOM   7108 C  CD1 . LEU D 1 116 ? -3.65720  12.30360  -3.55601  1.000 32.45978 ? 114 LEU D CD1 1 
ATOM   7109 C  CD2 . LEU D 1 116 ? -4.48914  11.04005  -5.65109  1.000 35.28160 ? 114 LEU D CD2 1 
ATOM   7110 N  N   . LEU D 1 117 ? -5.15360  15.39237  -4.32432  1.000 34.48250 ? 115 LEU D N   1 
ATOM   7111 C  CA  . LEU D 1 117 ? -5.90615  15.82388  -3.15501  1.000 33.81298 ? 115 LEU D CA  1 
ATOM   7112 C  C   . LEU D 1 117 ? -7.30609  16.28431  -3.54271  1.000 35.74547 ? 115 LEU D C   1 
ATOM   7113 O  O   . LEU D 1 117 ? -8.27989  15.95381  -2.85974  1.000 37.25595 ? 115 LEU D O   1 
ATOM   7114 C  CB  . LEU D 1 117 ? -5.13692  16.91989  -2.42808  1.000 29.63983 ? 115 LEU D CB  1 
ATOM   7115 C  CG  . LEU D 1 117 ? -3.78959  16.46833  -1.88363  1.000 29.30796 ? 115 LEU D CG  1 
ATOM   7116 C  CD1 . LEU D 1 117 ? -3.10455  17.65083  -1.20394  1.000 36.23092 ? 115 LEU D CD1 1 
ATOM   7117 C  CD2 . LEU D 1 117 ? -4.01758  15.32924  -0.90472  1.000 35.37825 ? 115 LEU D CD2 1 
ATOM   7118 N  N   . MET D 1 118 ? -7.43907  17.02410  -4.65125  1.000 34.48900 ? 116 MET D N   1 
ATOM   7119 C  CA  . MET D 1 118 ? -8.76800  17.47352  -5.06031  1.000 33.99183 ? 116 MET D CA  1 
ATOM   7120 C  C   . MET D 1 118 ? -9.65868  16.26603  -5.38179  1.000 38.22918 ? 116 MET D C   1 
ATOM   7121 O  O   . MET D 1 118 ? -10.81703 16.18942  -4.95550  1.000 37.41192 ? 116 MET D O   1 
ATOM   7122 C  CB  . MET D 1 118 ? -8.66145  18.37432  -6.28170  1.000 37.70755 ? 116 MET D CB  1 
ATOM   7123 C  CG  . MET D 1 118 ? -8.32473  19.86292  -6.04134  1.000 36.73396 ? 116 MET D CG  1 
ATOM   7124 S  SD  . MET D 1 118 ? -8.85066  20.73539  -4.53778  1.000 40.48284 ? 116 MET D SD  1 
ATOM   7125 C  CE  . MET D 1 118 ? -7.58331  20.29141  -3.34377  1.000 35.80311 ? 116 MET D CE  1 
ATOM   7126 N  N   . MET D 1 119 ? -9.12500  15.31294  -6.15277  1.000 35.04609 ? 117 MET D N   1 
ATOM   7127 C  CA  . MET D 1 119 ? -9.85662  14.08781  -6.46571  1.000 35.92650 ? 117 MET D CA  1 
ATOM   7128 C  C   . MET D 1 119 ? -10.12700 13.26086  -5.21650  1.000 34.99363 ? 117 MET D C   1 
ATOM   7129 O  O   . MET D 1 119 ? -11.23857 12.73859  -5.03611  1.000 34.96817 ? 117 MET D O   1 
ATOM   7130 C  CB  . MET D 1 119 ? -9.07711  13.26584  -7.50855  1.000 33.53100 ? 117 MET D CB  1 
ATOM   7131 C  CG  . MET D 1 119 ? -9.38049  13.72313  -8.92272  1.000 37.86758 ? 117 MET D CG  1 
ATOM   7132 S  SD  . MET D 1 119 ? -8.46745  12.88996  -10.25137 1.000 39.50332 ? 117 MET D SD  1 
ATOM   7133 C  CE  . MET D 1 119 ? -6.82033  12.71493  -9.55143  1.000 35.79341 ? 117 MET D CE  1 
ATOM   7134 N  N   . ARG D 1 120 ? -9.11672  13.11610  -4.35428  1.000 34.41790 ? 118 ARG D N   1 
ATOM   7135 C  CA  . ARG D 1 120 ? -9.26311  12.30609  -3.14713  1.000 38.72888 ? 118 ARG D CA  1 
ATOM   7136 C  C   . ARG D 1 120 ? -10.37596 12.84084  -2.25921  1.000 38.52033 ? 118 ARG D C   1 
ATOM   7137 O  O   . ARG D 1 120 ? -11.08786 12.06797  -1.61327  1.000 38.54218 ? 118 ARG D O   1 
ATOM   7138 C  CB  . ARG D 1 120 ? -7.94698  12.28773  -2.38249  1.000 38.26757 ? 118 ARG D CB  1 
ATOM   7139 C  CG  . ARG D 1 120 ? -7.78461  11.19969  -1.43385  1.000 43.61514 ? 118 ARG D CG  1 
ATOM   7140 C  CD  . ARG D 1 120 ? -6.41399  11.24491  -0.82845  1.000 42.35743 ? 118 ARG D CD  1 
ATOM   7141 N  NE  . ARG D 1 120 ? -6.58252  11.61626  0.56149   1.000 54.19371 ? 118 ARG D NE  1 
ATOM   7142 C  CZ  . ARG D 1 120 ? -6.31337  10.83448  1.59267   1.000 50.27731 ? 118 ARG D CZ  1 
ATOM   7143 N  NH1 . ARG D 1 120 ? -5.74323  9.65975   1.43384   1.000 48.86204 ? 118 ARG D NH1 1 
ATOM   7144 N  NH2 . ARG D 1 120 ? -6.62893  11.24952  2.81473   1.000 49.26879 ? 118 ARG D NH2 1 
ATOM   7145 N  N   . ASN D 1 121 ? -10.52931 14.16810  -2.20820  1.000 38.44231 ? 119 ASN D N   1 
ATOM   7146 C  CA  . ASN D 1 121 ? -11.55725 14.77143  -1.37373  1.000 40.72615 ? 119 ASN D CA  1 
ATOM   7147 C  C   . ASN D 1 121 ? -12.95376 14.35842  -1.81980  1.000 42.24634 ? 119 ASN D C   1 
ATOM   7148 O  O   . ASN D 1 121 ? -13.87468 14.35593  -0.99872  1.000 41.85489 ? 119 ASN D O   1 
ATOM   7149 C  CB  . ASN D 1 121 ? -11.40331 16.30590  -1.38103  1.000 39.85324 ? 119 ASN D CB  1 
ATOM   7150 C  CG  . ASN D 1 121 ? -10.26518 16.79084  -0.48584  1.000 37.71936 ? 119 ASN D CG  1 
ATOM   7151 O  OD1 . ASN D 1 121 ? -9.71288  16.02897  0.30833   1.000 37.41263 ? 119 ASN D OD1 1 
ATOM   7152 N  ND2 . ASN D 1 121 ? -9.92609  18.07615  -0.59642  1.000 39.38058 ? 119 ASN D ND2 1 
ATOM   7153 N  N   . ALA D 1 122 ? -13.11929 13.94429  -3.07736  1.000 38.99903 ? 120 ALA D N   1 
ATOM   7154 C  CA  . ALA D 1 122 ? -14.42135 13.55872  -3.60866  1.000 37.02515 ? 120 ALA D CA  1 
ATOM   7155 C  C   . ALA D 1 122 ? -14.62453 12.04686  -3.73852  1.000 43.27080 ? 120 ALA D C   1 
ATOM   7156 O  O   . ALA D 1 122 ? -15.72647 11.61260  -4.10096  1.000 39.42332 ? 120 ALA D O   1 
ATOM   7157 C  CB  . ALA D 1 122 ? -14.62864 14.22841  -4.97029  1.000 44.24475 ? 120 ALA D CB  1 
ATOM   7158 N  N   . LEU D 1 123 ? -13.60533 11.23579  -3.44689  1.000 39.74236 ? 121 LEU D N   1 
ATOM   7159 C  CA  . LEU D 1 123 ? -13.68799 9.79628   -3.63174  1.000 41.02522 ? 121 LEU D CA  1 
ATOM   7160 C  C   . LEU D 1 123 ? -14.46057 9.15059   -2.49402  1.000 44.21832 ? 121 LEU D C   1 
ATOM   7161 O  O   . LEU D 1 123 ? -14.50840 9.69402   -1.39093  1.000 46.18532 ? 121 LEU D O   1 
ATOM   7162 C  CB  . LEU D 1 123 ? -12.29451 9.18098   -3.68529  1.000 39.50028 ? 121 LEU D CB  1 
ATOM   7163 C  CG  . LEU D 1 123 ? -11.55582 9.38955   -4.99603  1.000 42.80777 ? 121 LEU D CG  1 
ATOM   7164 C  CD1 . LEU D 1 123 ? -10.14150 8.88185   -4.81304  1.000 44.88288 ? 121 LEU D CD1 1 
ATOM   7165 C  CD2 . LEU D 1 123 ? -12.26744 8.69064   -6.15834  1.000 40.38297 ? 121 LEU D CD2 1 
ATOM   7166 N  N   . PRO D 1 124 ? -15.04551 7.96963   -2.73216  1.000 44.91581 ? 122 PRO D N   1 
ATOM   7167 C  CA  . PRO D 1 124 ? -15.82442 7.30662   -1.68253  1.000 45.37685 ? 122 PRO D CA  1 
ATOM   7168 C  C   . PRO D 1 124 ? -14.94057 6.91435   -0.51408  1.000 48.28291 ? 122 PRO D C   1 
ATOM   7169 O  O   . PRO D 1 124 ? -13.70908 6.85409   -0.60814  1.000 47.70835 ? 122 PRO D O   1 
ATOM   7170 C  CB  . PRO D 1 124 ? -16.38775 6.06332   -2.38048  1.000 45.15280 ? 122 PRO D CB  1 
ATOM   7171 C  CG  . PRO D 1 124 ? -16.23955 6.32282   -3.86488  1.000 44.29633 ? 122 PRO D CG  1 
ATOM   7172 C  CD  . PRO D 1 124 ? -15.01693 7.17333   -3.97163  1.000 43.51491 ? 122 PRO D CD  1 
ATOM   7173 N  N   . GLU D 1 125 ? -15.60172 6.63152   0.59900   1.000 51.24872 ? 123 GLU D N   1 
ATOM   7174 C  CA  . GLU D 1 125 ? -14.90788 6.18072   1.79257   1.000 51.84226 ? 123 GLU D CA  1 
ATOM   7175 C  C   . GLU D 1 125 ? -14.39429 4.76047   1.59322   1.000 48.15891 ? 123 GLU D C   1 
ATOM   7176 O  O   . GLU D 1 125 ? -15.06083 3.92303   0.97093   1.000 48.64069 ? 123 GLU D O   1 
ATOM   7177 C  CB  . GLU D 1 125 ? -15.85076 6.24532   2.99905   1.000 51.43742 ? 123 GLU D CB  1 
ATOM   7178 C  CG  . GLU D 1 125 ? -15.15121 6.14361   4.33753   1.000 56.05214 ? 123 GLU D CG  1 
ATOM   7179 C  CD  . GLU D 1 125 ? -16.10115 5.84123   5.48927   1.000 63.35610 ? 123 GLU D CD  1 
ATOM   7180 O  OE1 . GLU D 1 125 ? -17.30669 6.15440   5.36721   1.000 63.29213 ? 123 GLU D OE1 1 
ATOM   7181 O  OE2 . GLU D 1 125 ? -15.63029 5.32273   6.52822   1.000 62.35691 ? 123 GLU D OE2 1 
ATOM   7182 N  N   . ASP D 1 126 ? -13.20097 4.49207   2.12798   1.000 48.22531 ? 124 ASP D N   1 
ATOM   7183 C  CA  . ASP D 1 126 ? -12.57773 3.16496   2.06239   1.000 48.39782 ? 124 ASP D CA  1 
ATOM   7184 C  C   . ASP D 1 126 ? -12.50367 2.65010   0.62581   1.000 44.90759 ? 124 ASP D C   1 
ATOM   7185 O  O   . ASP D 1 126 ? -12.85734 1.50683   0.31559   1.000 42.05458 ? 124 ASP D O   1 
ATOM   7186 C  CB  . ASP D 1 126 ? -13.29237 2.15780   2.97173   1.000 46.23801 ? 124 ASP D CB  1 
ATOM   7187 C  CG  . ASP D 1 126 ? -12.47408 0.86901   3.17422   1.000 48.79700 ? 124 ASP D CG  1 
ATOM   7188 O  OD1 . ASP D 1 126 ? -11.24346 0.95074   3.39741   1.000 48.17712 ? 124 ASP D OD1 1 
ATOM   7189 O  OD2 . ASP D 1 126 ? -13.07102 -0.23113  3.13317   1.000 53.21264 ? 124 ASP D OD2 1 
ATOM   7190 N  N   . ALA D 1 127 ? -12.05146 3.52125   -0.25809  1.000 42.00300 ? 125 ALA D N   1 
ATOM   7191 C  CA  . ALA D 1 127 ? -11.62688 3.12969   -1.59206  1.000 38.52265 ? 125 ALA D CA  1 
ATOM   7192 C  C   . ALA D 1 127 ? -10.11347 2.98472   -1.50057  1.000 41.24220 ? 125 ALA D C   1 
ATOM   7193 O  O   . ALA D 1 127 ? -9.38503  3.97994   -1.51684  1.000 42.48844 ? 125 ALA D O   1 
ATOM   7194 C  CB  . ALA D 1 127 ? -12.06875 4.15462   -2.62583  1.000 40.57187 ? 125 ALA D CB  1 
ATOM   7195 N  N   . THR D 1 128 ? -9.64733  1.72922   -1.40417  1.000 41.75741 ? 126 THR D N   1 
ATOM   7196 C  CA  . THR D 1 128 ? -8.28039  1.38026   -1.02755  1.000 40.89666 ? 126 THR D CA  1 
ATOM   7197 C  C   . THR D 1 128 ? -7.81069  0.19904   -1.86380  1.000 39.61142 ? 126 THR D C   1 
ATOM   7198 O  O   . THR D 1 128 ? -8.59742  -0.70284  -2.16158  1.000 37.42074 ? 126 THR D O   1 
ATOM   7199 C  CB  . THR D 1 128 ? -8.20468  0.99700   0.46581   1.000 47.09732 ? 126 THR D CB  1 
ATOM   7200 O  OG1 . THR D 1 128 ? -6.95249  0.36532   0.75386   1.000 44.41259 ? 126 THR D OG1 1 
ATOM   7201 C  CG2 . THR D 1 128 ? -9.34068  -0.00196  0.83655   1.000 44.72618 ? 126 THR D CG2 1 
ATOM   7202 N  N   . GLY D 1 129 ? -6.52460  0.19425   -2.21801  1.000 37.61995 ? 127 GLY D N   1 
ATOM   7203 C  CA  . GLY D 1 129 ? -5.90963  -0.91948  -2.94633  1.000 35.36494 ? 127 GLY D CA  1 
ATOM   7204 C  C   . GLY D 1 129 ? -5.76683  -2.18704  -2.14165  1.000 35.96585 ? 127 GLY D C   1 
ATOM   7205 O  O   . GLY D 1 129 ? -5.44789  -3.23769  -2.70962  1.000 35.22954 ? 127 GLY D O   1 
ATOM   7206 N  N   . LEU D 1 130 ? -6.02790  -2.13186  -0.83475  1.000 39.43529 ? 128 LEU D N   1 
ATOM   7207 C  CA  . LEU D 1 130 ? -6.25858  -3.38449  -0.12336  1.000 35.25952 ? 128 LEU D CA  1 
ATOM   7208 C  C   . LEU D 1 130 ? -7.38374  -4.19208  -0.76691  1.000 35.44453 ? 128 LEU D C   1 
ATOM   7209 O  O   . LEU D 1 130 ? -7.42497  -5.41496  -0.59267  1.000 37.93116 ? 128 LEU D O   1 
ATOM   7210 C  CB  . LEU D 1 130 ? -6.56008  -3.10534  1.35907   1.000 39.80100 ? 128 LEU D CB  1 
ATOM   7211 C  CG  . LEU D 1 130 ? -5.38661  -2.53810  2.17633   1.000 40.35691 ? 128 LEU D CG  1 
ATOM   7212 C  CD1 . LEU D 1 130 ? -5.85871  -1.78778  3.42049   1.000 45.38692 ? 128 LEU D CD1 1 
ATOM   7213 C  CD2 . LEU D 1 130 ? -4.40713  -3.64517  2.53883   1.000 46.00755 ? 128 LEU D CD2 1 
ATOM   7214 N  N   . ASP D 1 131 ? -8.31213  -3.55521  -1.49234  1.000 32.40405 ? 129 ASP D N   1 
ATOM   7215 C  CA  . ASP D 1 131 ? -9.26635  -4.31918  -2.30610  1.000 36.33389 ? 129 ASP D CA  1 
ATOM   7216 C  C   . ASP D 1 131 ? -8.85082  -4.57724  -3.74187  1.000 36.62283 ? 129 ASP D C   1 
ATOM   7217 O  O   . ASP D 1 131 ? -9.68883  -5.05101  -4.52238  1.000 32.52239 ? 129 ASP D O   1 
ATOM   7218 C  CB  . ASP D 1 131 ? -10.67177 -3.70280  -2.29123  1.000 34.51823 ? 129 ASP D CB  1 
ATOM   7219 C  CG  . ASP D 1 131 ? -11.20837 -3.53705  -0.88684  1.000 40.86533 ? 129 ASP D CG  1 
ATOM   7220 O  OD1 . ASP D 1 131 ? -11.45420 -4.61782  -0.29964  1.000 39.48892 ? 129 ASP D OD1 1 
ATOM   7221 O  OD2 . ASP D 1 131 ? -11.45895 -2.43240  -0.41127  1.000 39.25464 ? 129 ASP D OD2 1 
ATOM   7222 N  N   . SER D 1 132 ? -7.59380  -4.31854  -4.10369  1.000 37.23733 ? 130 SER D N   1 
ATOM   7223 C  CA  . SER D 1 132 ? -7.13395  -4.67796  -5.44507  1.000 31.04199 ? 130 SER D CA  1 
ATOM   7224 C  C   . SER D 1 132 ? -7.24395  -6.18526  -5.64639  1.000 33.23864 ? 130 SER D C   1 
ATOM   7225 O  O   . SER D 1 132 ? -6.63329  -6.94646  -4.88732  1.000 32.51119 ? 130 SER D O   1 
ATOM   7226 C  CB  . SER D 1 132 ? -5.69016  -4.23817  -5.67639  1.000 30.13402 ? 130 SER D CB  1 
ATOM   7227 O  OG  . SER D 1 132 ? -5.16086  -4.93516  -6.81096  1.000 31.58490 ? 130 SER D OG  1 
ATOM   7228 N  N   . PRO D 1 133 ? -8.00269  -6.65347  -6.63612  1.000 31.97346 ? 131 PRO D N   1 
ATOM   7229 C  CA  . PRO D 1 133 ? -7.99010  -8.09530  -6.93780  1.000 34.11140 ? 131 PRO D CA  1 
ATOM   7230 C  C   . PRO D 1 133 ? -6.60097  -8.58778  -7.30781  1.000 32.92991 ? 131 PRO D C   1 
ATOM   7231 O  O   . PRO D 1 133 ? -6.21689  -9.68937  -6.90591  1.000 34.32295 ? 131 PRO D O   1 
ATOM   7232 C  CB  . PRO D 1 133 ? -8.96966  -8.23197  -8.11340  1.000 35.60885 ? 131 PRO D CB  1 
ATOM   7233 C  CG  . PRO D 1 133 ? -9.68059  -6.90208  -8.23086  1.000 35.10804 ? 131 PRO D CG  1 
ATOM   7234 C  CD  . PRO D 1 133 ? -8.88428  -5.86877  -7.51816  1.000 33.66944 ? 131 PRO D CD  1 
ATOM   7235 N  N   . GLY D 1 134 ? -5.83894  -7.79549  -8.06480  1.000 31.60318 ? 132 GLY D N   1 
ATOM   7236 C  CA  . GLY D 1 134 ? -4.46294  -8.16615  -8.38090  1.000 31.96733 ? 132 GLY D CA  1 
ATOM   7237 C  C   . GLY D 1 134 ? -3.63648  -8.46547  -7.14166  1.000 35.95627 ? 132 GLY D C   1 
ATOM   7238 O  O   . GLY D 1 134 ? -3.00310  -9.51931  -7.03297  1.000 33.56965 ? 132 GLY D O   1 
ATOM   7239 N  N   . TYR D 1 135 ? -3.64758  -7.55695  -6.17699  1.000 32.70569 ? 133 TYR D N   1 
ATOM   7240 C  CA  . TYR D 1 135 ? -2.79205  -7.74527  -5.00753  1.000 36.47993 ? 133 TYR D CA  1 
ATOM   7241 C  C   . TYR D 1 135 ? -3.31918  -8.86365  -4.11754  1.000 34.60292 ? 133 TYR D C   1 
ATOM   7242 O  O   . TYR D 1 135 ? -2.53415  -9.64157  -3.56224  1.000 36.34892 ? 133 TYR D O   1 
ATOM   7243 C  CB  . TYR D 1 135 ? -2.67205  -6.41911  -4.23565  1.000 38.27476 ? 133 TYR D CB  1 
ATOM   7244 C  CG  . TYR D 1 135 ? -2.41805  -6.51194  -2.73236  1.000 40.37369 ? 133 TYR D CG  1 
ATOM   7245 C  CD1 . TYR D 1 135 ? -3.47513  -6.58242  -1.82705  1.000 41.47735 ? 133 TYR D CD1 1 
ATOM   7246 C  CD2 . TYR D 1 135 ? -1.11735  -6.47962  -2.22417  1.000 41.74702 ? 133 TYR D CD2 1 
ATOM   7247 C  CE1 . TYR D 1 135 ? -3.25155  -6.65676  -0.44541  1.000 45.10128 ? 133 TYR D CE1 1 
ATOM   7248 C  CE2 . TYR D 1 135 ? -0.87757  -6.55407  -0.85484  1.000 45.19482 ? 133 TYR D CE2 1 
ATOM   7249 C  CZ  . TYR D 1 135 ? -1.95083  -6.63817  0.03076   1.000 49.01245 ? 133 TYR D CZ  1 
ATOM   7250 O  OH  . TYR D 1 135 ? -1.73438  -6.70046  1.39476   1.000 55.96236 ? 133 TYR D OH  1 
ATOM   7251 N  N   . ARG D 1 136 ? -4.64405  -8.96013  -3.96806  1.000 32.71633 ? 134 ARG D N   1 
ATOM   7252 C  CA  . ARG D 1 136 ? -5.21660  -9.97682  -3.09084  1.000 34.98445 ? 134 ARG D CA  1 
ATOM   7253 C  C   . ARG D 1 136 ? -4.97628  -11.38954 -3.63846  1.000 36.74633 ? 134 ARG D C   1 
ATOM   7254 O  O   . ARG D 1 136 ? -4.65525  -12.31910 -2.88702  1.000 33.27810 ? 134 ARG D O   1 
ATOM   7255 C  CB  . ARG D 1 136 ? -6.70951  -9.72133  -2.91744  1.000 35.99515 ? 134 ARG D CB  1 
ATOM   7256 C  CG  . ARG D 1 136 ? -7.02697  -8.51070  -2.02607  1.000 36.14536 ? 134 ARG D CG  1 
ATOM   7257 C  CD  . ARG D 1 136 ? -8.46771  -8.07284  -2.26461  1.000 39.20345 ? 134 ARG D CD  1 
ATOM   7258 N  NE  . ARG D 1 136 ? -9.43926  -8.98430  -1.66095  1.000 46.66962 ? 134 ARG D NE  1 
ATOM   7259 C  CZ  . ARG D 1 136 ? -9.75270  -9.02650  -0.36814  1.000 50.81959 ? 134 ARG D CZ  1 
ATOM   7260 N  NH1 . ARG D 1 136 ? -9.17850  -8.22438  0.51825   1.000 47.42516 ? 134 ARG D NH1 1 
ATOM   7261 N  NH2 . ARG D 1 136 ? -10.69067 -9.87448  0.04221   1.000 49.33357 ? 134 ARG D NH2 1 
ATOM   7262 N  N   . ASN D 1 137 ? -5.13094  -11.56981 -4.94428  1.000 31.68786 ? 135 ASN D N   1 
ATOM   7263 C  CA  . ASN D 1 137 ? -4.95985  -12.89968 -5.49866  1.000 32.63806 ? 135 ASN D CA  1 
ATOM   7264 C  C   . ASN D 1 137 ? -3.48587  -13.26836 -5.60333  1.000 34.04608 ? 135 ASN D C   1 
ATOM   7265 O  O   . ASN D 1 137 ? -3.13942  -14.45365 -5.51500  1.000 36.47036 ? 135 ASN D O   1 
ATOM   7266 C  CB  . ASN D 1 137 ? -5.67181  -12.96612 -6.84322  1.000 32.63686 ? 135 ASN D CB  1 
ATOM   7267 C  CG  . ASN D 1 137 ? -7.17611  -12.94331 -6.69330  1.000 35.49591 ? 135 ASN D CG  1 
ATOM   7268 O  OD1 . ASN D 1 137 ? -7.74144  -13.74281 -5.94002  1.000 35.20646 ? 135 ASN D OD1 1 
ATOM   7269 N  ND2 . ASN D 1 137 ? -7.83826  -12.03333 -7.40903  1.000 32.26023 ? 135 ASN D ND2 1 
ATOM   7270 N  N   . LEU D 1 138 ? -2.61636  -12.27329 -5.80504  1.000 35.73093 ? 136 LEU D N   1 
ATOM   7271 C  CA  . LEU D 1 138 ? -1.17414  -12.49624 -5.73222  1.000 35.51917 ? 136 LEU D CA  1 
ATOM   7272 C  C   . LEU D 1 138 ? -0.75902  -12.97833 -4.35288  1.000 35.48304 ? 136 LEU D C   1 
ATOM   7273 O  O   . LEU D 1 138 ? 0.01626   -13.93500 -4.23055  1.000 36.68913 ? 136 LEU D O   1 
ATOM   7274 C  CB  . LEU D 1 138 ? -0.43030  -11.21009 -6.10738  1.000 34.46949 ? 136 LEU D CB  1 
ATOM   7275 C  CG  . LEU D 1 138 ? -0.25909  -11.02834 -7.61488  1.000 37.00151 ? 136 LEU D CG  1 
ATOM   7276 C  CD1 . LEU D 1 138 ? 0.95033   -10.15603 -7.94896  1.000 39.60496 ? 136 LEU D CD1 1 
ATOM   7277 C  CD2 . LEU D 1 138 ? -0.07439  -12.42748 -8.19151  1.000 39.87069 ? 136 LEU D CD2 1 
ATOM   7278 N  N   . ARG D 1 139 ? -1.24535  -12.31679 -3.29311  1.000 34.98377 ? 137 ARG D N   1 
ATOM   7279 C  CA  A ARG D 1 139 ? -0.92223  -12.78239 -1.94843  0.492 37.81372 ? 137 ARG D CA  1 
ATOM   7280 C  CA  B ARG D 1 139 ? -0.93051  -12.78025 -1.94472  0.508 37.81824 ? 137 ARG D CA  1 
ATOM   7281 C  C   . ARG D 1 139 ? -1.51419  -14.16200 -1.69011  1.000 35.57039 ? 137 ARG D C   1 
ATOM   7282 O  O   . ARG D 1 139 ? -0.86355  -15.00598 -1.07018  1.000 38.41218 ? 137 ARG D O   1 
ATOM   7283 C  CB  A ARG D 1 139 ? -1.39583  -11.77940 -0.89546  0.492 39.92184 ? 137 ARG D CB  1 
ATOM   7284 C  CB  B ARG D 1 139 ? -1.43385  -11.78831 -0.89908  0.508 39.92042 ? 137 ARG D CB  1 
ATOM   7285 C  CG  A ARG D 1 139 ? -0.53507  -10.50519 -0.81097  0.492 42.61161 ? 137 ARG D CG  1 
ATOM   7286 C  CG  B ARG D 1 139 ? -0.38440  -10.76055 -0.49504  0.508 43.26541 ? 137 ARG D CG  1 
ATOM   7287 C  CD  A ARG D 1 139 ? 0.10891   -10.35237 0.57709   0.492 44.45335 ? 137 ARG D CD  1 
ATOM   7288 C  CD  B ARG D 1 139 ? -0.90805  -9.77836  0.54237   0.508 42.56891 ? 137 ARG D CD  1 
ATOM   7289 N  NE  A ARG D 1 139 ? 1.35764   -11.10182 0.70545   0.492 43.00320 ? 137 ARG D NE  1 
ATOM   7290 N  NE  B ARG D 1 139 ? -1.22433  -10.41059 1.81620   0.508 41.29164 ? 137 ARG D NE  1 
ATOM   7291 C  CZ  A ARG D 1 139 ? 2.52629   -10.71369 0.21190   0.492 41.05534 ? 137 ARG D CZ  1 
ATOM   7292 C  CZ  B ARG D 1 139 ? -2.45504  -10.57463 2.28174   0.508 44.58838 ? 137 ARG D CZ  1 
ATOM   7293 N  NH1 A ARG D 1 139 ? 2.64715   -9.59457  -0.48812  0.492 42.01961 ? 137 ARG D NH1 1 
ATOM   7294 N  NH1 B ARG D 1 139 ? -3.51368  -10.18243 1.59096   0.508 45.16417 ? 137 ARG D NH1 1 
ATOM   7295 N  NH2 A ARG D 1 139 ? 3.60115   -11.46390 0.42960   0.492 38.95490 ? 137 ARG D NH2 1 
ATOM   7296 N  NH2 B ARG D 1 139 ? -2.62877  -11.13865 3.47351   0.508 45.22036 ? 137 ARG D NH2 1 
ATOM   7297 N  N   . ARG D 1 140 ? -2.74716  -14.40915 -2.16040  1.000 33.93055 ? 138 ARG D N   1 
ATOM   7298 C  CA  . ARG D 1 140 ? -3.33899  -15.74910 -2.09329  1.000 34.22604 ? 138 ARG D CA  1 
ATOM   7299 C  C   . ARG D 1 140 ? -2.39628  -16.80304 -2.67673  1.000 37.52848 ? 138 ARG D C   1 
ATOM   7300 O  O   . ARG D 1 140 ? -2.05937  -17.79858 -2.02197  1.000 34.42455 ? 138 ARG D O   1 
ATOM   7301 C  CB  . ARG D 1 140 ? -4.67939  -15.79708 -2.85159  1.000 33.53611 ? 138 ARG D CB  1 
ATOM   7302 C  CG  . ARG D 1 140 ? -5.76192  -16.74144 -2.26346  1.000 45.44701 ? 138 ARG D CG  1 
ATOM   7303 C  CD  . ARG D 1 140 ? -7.02504  -16.82693 -3.16175  1.000 40.55560 ? 138 ARG D CD  1 
ATOM   7304 N  NE  . ARG D 1 140 ? -7.63959  -15.55134 -3.54247  1.000 44.08815 ? 138 ARG D NE  1 
ATOM   7305 C  CZ  . ARG D 1 140 ? -7.95080  -14.55756 -2.71548  1.000 47.32043 ? 138 ARG D CZ  1 
ATOM   7306 N  NH1 . ARG D 1 140 ? -7.83825  -14.68485 -1.39990  1.000 53.23679 ? 138 ARG D NH1 1 
ATOM   7307 N  NH2 . ARG D 1 140 ? -8.44192  -13.42211 -3.21693  1.000 47.00582 ? 138 ARG D NH2 1 
ATOM   7308 N  N   . VAL D 1 141 ? -1.98387  -16.60861 -3.93620  1.000 32.94628 ? 139 VAL D N   1 
ATOM   7309 C  CA  . VAL D 1 141 ? -1.28512  -17.65979 -4.67032  1.000 31.27179 ? 139 VAL D CA  1 
ATOM   7310 C  C   . VAL D 1 141 ? 0.17707   -17.77765 -4.27712  1.000 34.14850 ? 139 VAL D C   1 
ATOM   7311 O  O   . VAL D 1 141 ? 0.82469   -18.77437 -4.62700  1.000 36.13066 ? 139 VAL D O   1 
ATOM   7312 C  CB  . VAL D 1 141 ? -1.39372  -17.40253 -6.18877  1.000 33.50358 ? 139 VAL D CB  1 
ATOM   7313 C  CG1 . VAL D 1 141 ? -0.32960  -16.40854 -6.64036  1.000 31.21984 ? 139 VAL D CG1 1 
ATOM   7314 C  CG2 . VAL D 1 141 ? -1.28880  -18.72243 -6.99209  1.000 32.52828 ? 139 VAL D CG2 1 
ATOM   7315 N  N   . ALA D 1 142 ? 0.71786   -16.80778 -3.53758  1.000 34.79880 ? 140 ALA D N   1 
ATOM   7316 C  CA  . ALA D 1 142 ? 2.15355   -16.83306 -3.27380  1.000 35.80859 ? 140 ALA D CA  1 
ATOM   7317 C  C   . ALA D 1 142 ? 2.55813   -18.09067 -2.50779  1.000 33.92855 ? 140 ALA D C   1 
ATOM   7318 O  O   . ALA D 1 142 ? 3.60762   -18.68565 -2.78917  1.000 31.54120 ? 140 ALA D O   1 
ATOM   7319 C  CB  . ALA D 1 142 ? 2.57732   -15.57971 -2.51214  1.000 35.48636 ? 140 ALA D CB  1 
ATOM   7320 N  N   . ARG D 1 143 ? 1.75901   -18.50416 -1.52128  1.000 33.95042 ? 141 ARG D N   1 
ATOM   7321 C  CA  . ARG D 1 143 ? 2.12807   -19.73233 -0.81427  1.000 35.07999 ? 141 ARG D CA  1 
ATOM   7322 C  C   . ARG D 1 143 ? 1.99895   -20.96128 -1.69771  1.000 32.25771 ? 141 ARG D C   1 
ATOM   7323 O  O   . ARG D 1 143 ? 2.95213   -21.75410 -1.74107  1.000 32.99021 ? 141 ARG D O   1 
ATOM   7324 C  CB  . ARG D 1 143 ? 1.32954   -19.88504 0.48347   1.000 36.79070 ? 141 ARG D CB  1 
ATOM   7325 C  CG  . ARG D 1 143 ? 2.04062   -19.23385 1.66158   1.000 46.04869 ? 141 ARG D CG  1 
ATOM   7326 C  CD  . ARG D 1 143 ? 2.87252   -20.29197 2.38343   1.000 51.23885 ? 141 ARG D CD  1 
ATOM   7327 N  NE  . ARG D 1 143 ? 2.14882   -21.54872 2.54398   1.000 53.65155 ? 141 ARG D NE  1 
ATOM   7328 C  CZ  . ARG D 1 143 ? 2.55536   -22.56376 3.29729   1.000 51.04415 ? 141 ARG D CZ  1 
ATOM   7329 N  NH1 . ARG D 1 143 ? 3.72264   -22.53713 3.92909   1.000 47.24660 ? 141 ARG D NH1 1 
ATOM   7330 N  NH2 . ARG D 1 143 ? 1.78430   -23.64228 3.39777   1.000 48.98308 ? 141 ARG D NH2 1 
ATOM   7331 N  N   . PRO D 1 144 ? 0.87175   -21.20911 -2.38635  1.000 33.71648 ? 142 PRO D N   1 
ATOM   7332 C  CA  . PRO D 1 144 ? 0.82476   -22.34534 -3.32233  1.000 32.60754 ? 142 PRO D CA  1 
ATOM   7333 C  C   . PRO D 1 144 ? 2.03457   -22.39526 -4.23865  1.000 33.43587 ? 142 PRO D C   1 
ATOM   7334 O  O   . PRO D 1 144 ? 2.54286   -23.48132 -4.56311  1.000 34.32095 ? 142 PRO D O   1 
ATOM   7335 C  CB  . PRO D 1 144 ? -0.46216  -22.07909 -4.11902  1.000 33.83284 ? 142 PRO D CB  1 
ATOM   7336 C  CG  . PRO D 1 144 ? -1.33215  -21.32926 -3.18869  1.000 34.33418 ? 142 PRO D CG  1 
ATOM   7337 C  CD  . PRO D 1 144 ? -0.43701  -20.53132 -2.28070  1.000 32.54003 ? 142 PRO D CD  1 
ATOM   7338 N  N   . VAL D 1 145 ? 2.52090   -21.22328 -4.65806  1.000 31.67184 ? 143 VAL D N   1 
ATOM   7339 C  CA  . VAL D 1 145 ? 3.64846   -21.17788 -5.58249  1.000 33.34053 ? 143 VAL D CA  1 
ATOM   7340 C  C   . VAL D 1 145 ? 4.92658   -21.59601 -4.86817  1.000 31.67126 ? 143 VAL D C   1 
ATOM   7341 O  O   . VAL D 1 145 ? 5.70718   -22.39931 -5.37923  1.000 28.44224 ? 143 VAL D O   1 
ATOM   7342 C  CB  . VAL D 1 145 ? 3.79202   -19.76879 -6.19045  1.000 30.92556 ? 143 VAL D CB  1 
ATOM   7343 C  CG1 . VAL D 1 145 ? 5.12229   -19.66732 -6.88847  1.000 32.77361 ? 143 VAL D CG1 1 
ATOM   7344 C  CG2 . VAL D 1 145 ? 2.61544   -19.43283 -7.11780  1.000 29.48576 ? 143 VAL D CG2 1 
ATOM   7345 N  N   . TRP D 1 146 ? 5.17594   -21.03462 -3.68433  1.000 34.75351 ? 144 TRP D N   1 
ATOM   7346 C  CA  . TRP D 1 146 ? 6.37939   -21.41925 -2.95824  1.000 36.87307 ? 144 TRP D CA  1 
ATOM   7347 C  C   . TRP D 1 146 ? 6.36330   -22.91553 -2.64245  1.000 36.01024 ? 144 TRP D C   1 
ATOM   7348 O  O   . TRP D 1 146 ? 7.37895   -23.60333 -2.79916  1.000 32.70462 ? 144 TRP D O   1 
ATOM   7349 C  CB  . TRP D 1 146 ? 6.53237   -20.60122 -1.66638  1.000 36.15978 ? 144 TRP D CB  1 
ATOM   7350 C  CG  . TRP D 1 146 ? 7.57502   -21.23884 -0.84914  1.000 38.80290 ? 144 TRP D CG  1 
ATOM   7351 C  CD1 . TRP D 1 146 ? 7.40271   -22.08397 0.22887   1.000 41.34974 ? 144 TRP D CD1 1 
ATOM   7352 C  CD2 . TRP D 1 146 ? 8.96574   -21.25713 -1.15101  1.000 39.82968 ? 144 TRP D CD2 1 
ATOM   7353 N  NE1 . TRP D 1 146 ? 8.63006   -22.56066 0.65082   1.000 36.93687 ? 144 TRP D NE1 1 
ATOM   7354 C  CE2 . TRP D 1 146 ? 9.60236   -22.05891 -0.17437  1.000 42.21140 ? 144 TRP D CE2 1 
ATOM   7355 C  CE3 . TRP D 1 146 ? 9.73945   -20.65074 -2.13695  1.000 38.69022 ? 144 TRP D CE3 1 
ATOM   7356 C  CZ2 . TRP D 1 146 ? 10.97537  -22.26280 -0.16397  1.000 45.61145 ? 144 TRP D CZ2 1 
ATOM   7357 C  CZ3 . TRP D 1 146 ? 11.08652  -20.84737 -2.11843  1.000 45.95011 ? 144 TRP D CZ3 1 
ATOM   7358 C  CH2 . TRP D 1 146 ? 11.70255  -21.64928 -1.13573  1.000 43.57394 ? 144 TRP D CH2 1 
ATOM   7359 N  N   . LYS D 1 147 ? 5.20260   -23.42338 -2.22021  1.000 36.80354 ? 145 LYS D N   1 
ATOM   7360 C  CA  . LYS D 1 147 ? 5.02853   -24.83870 -1.89071  1.000 37.91665 ? 145 LYS D CA  1 
ATOM   7361 C  C   . LYS D 1 147 ? 5.40897   -25.73290 -3.06485  1.000 40.22156 ? 145 LYS D C   1 
ATOM   7362 O  O   . LYS D 1 147 ? 6.15477   -26.70864 -2.90549  1.000 36.03373 ? 145 LYS D O   1 
ATOM   7363 C  CB  . LYS D 1 147 ? 3.57751   -25.06597 -1.48413  1.000 37.43916 ? 145 LYS D CB  1 
ATOM   7364 C  CG  . LYS D 1 147 ? 3.26198   -24.64066 -0.06356  1.000 45.34660 ? 145 LYS D CG  1 
ATOM   7365 C  CD  . LYS D 1 147 ? 4.39521   -25.07033 0.87657   1.000 48.00180 ? 145 LYS D CD  1 
ATOM   7366 C  CE  . LYS D 1 147 ? 3.96316   -26.40231 1.55157   1.000 50.97612 ? 145 LYS D CE  1 
ATOM   7367 N  NZ  . LYS D 1 147 ? 4.90028   -26.97821 2.57145   1.000 48.12941 ? 145 LYS D NZ  1 
ATOM   7368 N  N   . ALA D 1 148 ? 4.93224   -25.38953 -4.26387  1.000 36.81246 ? 146 ALA D N   1 
ATOM   7369 C  CA  . ALA D 1 148 ? 5.27664   -26.18883 -5.43484  1.000 33.20909 ? 146 ALA D CA  1 
ATOM   7370 C  C   . ALA D 1 148 ? 6.78186   -26.24658 -5.62432  1.000 34.54693 ? 146 ALA D C   1 
ATOM   7371 O  O   . ALA D 1 148 ? 7.34219   -27.31840 -5.89228  1.000 34.77852 ? 146 ALA D O   1 
ATOM   7372 C  CB  . ALA D 1 148 ? 4.58062   -25.62705 -6.66938  1.000 33.64901 ? 146 ALA D CB  1 
ATOM   7373 N  N   . TYR D 1 149 ? 7.46010   -25.09889 -5.50182  1.000 33.29510 ? 147 TYR D N   1 
ATOM   7374 C  CA  . TYR D 1 149 ? 8.91607   -25.10003 -5.62883  1.000 33.91850 ? 147 TYR D CA  1 
ATOM   7375 C  C   . TYR D 1 149 ? 9.56710   -25.94444 -4.53730  1.000 35.42812 ? 147 TYR D C   1 
ATOM   7376 O  O   . TYR D 1 149 ? 10.43227  -26.77623 -4.81630  1.000 34.08923 ? 147 TYR D O   1 
ATOM   7377 C  CB  . TYR D 1 149 ? 9.47904   -23.67654 -5.58058  1.000 31.36212 ? 147 TYR D CB  1 
ATOM   7378 C  CG  . TYR D 1 149 ? 10.96050  -23.70456 -5.75781  1.000 31.42400 ? 147 TYR D CG  1 
ATOM   7379 C  CD1 . TYR D 1 149 ? 11.51066  -24.07292 -6.98533  1.000 31.72734 ? 147 TYR D CD1 1 
ATOM   7380 C  CD2 . TYR D 1 149 ? 11.81807  -23.40578 -4.71455  1.000 32.31853 ? 147 TYR D CD2 1 
ATOM   7381 C  CE1 . TYR D 1 149 ? 12.86783  -24.15269 -7.16438  1.000 30.68369 ? 147 TYR D CE1 1 
ATOM   7382 C  CE2 . TYR D 1 149 ? 13.19921  -23.45482 -4.89235  1.000 32.31334 ? 147 TYR D CE2 1 
ATOM   7383 C  CZ  . TYR D 1 149 ? 13.70967  -23.83328 -6.12724  1.000 33.55646 ? 147 TYR D CZ  1 
ATOM   7384 O  OH  . TYR D 1 149 ? 15.06975  -23.89564 -6.33705  1.000 37.57678 ? 147 TYR D OH  1 
ATOM   7385 N  N   . GLU D 1 150 ? 9.19924   -25.69572 -3.27570  1.000 39.08510 ? 148 GLU D N   1 
ATOM   7386 C  CA  . GLU D 1 150 ? 9.79472   -26.42942 -2.16151  1.000 38.41893 ? 148 GLU D CA  1 
ATOM   7387 C  C   . GLU D 1 150 ? 9.61476   -27.93429 -2.33111  1.000 38.76263 ? 148 GLU D C   1 
ATOM   7388 O  O   . GLU D 1 150 ? 10.57663  -28.70204 -2.19226  1.000 38.51260 ? 148 GLU D O   1 
ATOM   7389 C  CB  . GLU D 1 150 ? 9.17963   -25.95312 -0.84610  1.000 39.63089 ? 148 GLU D CB  1 
ATOM   7390 C  CG  . GLU D 1 150 ? 9.80209   -26.55443 0.39556   1.000 45.02543 ? 148 GLU D CG  1 
ATOM   7391 C  CD  . GLU D 1 150 ? 9.25373   -25.91713 1.65911   1.000 50.59620 ? 148 GLU D CD  1 
ATOM   7392 O  OE1 . GLU D 1 150 ? 8.23849   -26.42057 2.17408   1.000 54.62023 ? 148 GLU D OE1 1 
ATOM   7393 O  OE2 . GLU D 1 150 ? 9.80074   -24.87741 2.10607   1.000 52.46659 ? 148 GLU D OE2 1 
ATOM   7394 N  N   . GLN D 1 151 ? 8.38280   -28.36863 -2.63723  1.000 36.20573 ? 149 GLN D N   1 
ATOM   7395 C  CA  . GLN D 1 151 ? 8.10655   -29.77960 -2.87740  1.000 35.73653 ? 149 GLN D CA  1 
ATOM   7396 C  C   . GLN D 1 151 ? 9.00566   -30.33542 -3.97985  1.000 40.98597 ? 149 GLN D C   1 
ATOM   7397 O  O   . GLN D 1 151 ? 9.60569   -31.40296 -3.82401  1.000 39.41762 ? 149 GLN D O   1 
ATOM   7398 C  CB  . GLN D 1 151 ? 6.62122   -29.97684 -3.23143  1.000 35.57064 ? 149 GLN D CB  1 
ATOM   7399 C  CG  . GLN D 1 151 ? 5.64652   -29.79507 -2.04629  1.000 37.73108 ? 149 GLN D CG  1 
ATOM   7400 C  CD  . GLN D 1 151 ? 4.20190   -29.51251 -2.48891  1.000 39.32526 ? 149 GLN D CD  1 
ATOM   7401 O  OE1 . GLN D 1 151 ? 3.90454   -29.44191 -3.68186  1.000 42.49394 ? 149 GLN D OE1 1 
ATOM   7402 N  NE2 . GLN D 1 151 ? 3.31393   -29.30204 -1.52251  1.000 39.81369 ? 149 GLN D NE2 1 
ATOM   7403 N  N   . ALA D 1 152 ? 9.11973   -29.62196 -5.10728  1.000 37.65546 ? 150 ALA D N   1 
ATOM   7404 C  CA  . ALA D 1 152 ? 9.97292   -30.11572 -6.18705  1.000 37.31438 ? 150 ALA D CA  1 
ATOM   7405 C  C   . ALA D 1 152 ? 11.41941  -30.23984 -5.72443  1.000 38.98082 ? 150 ALA D C   1 
ATOM   7406 O  O   . ALA D 1 152 ? 12.13258  -31.16504 -6.12879  1.000 38.16991 ? 150 ALA D O   1 
ATOM   7407 C  CB  . ALA D 1 152 ? 9.88744   -29.18329 -7.41404  1.000 35.58980 ? 150 ALA D CB  1 
ATOM   7408 N  N   . VAL D 1 153 ? 11.88051  -29.30422 -4.89223  1.000 36.07736 ? 151 VAL D N   1 
ATOM   7409 C  CA  . VAL D 1 153 ? 13.25291  -29.39336 -4.40956  1.000 39.58617 ? 151 VAL D CA  1 
ATOM   7410 C  C   . VAL D 1 153 ? 13.41543  -30.63963 -3.55501  1.000 43.09185 ? 151 VAL D C   1 
ATOM   7411 O  O   . VAL D 1 153 ? 14.43119  -31.34320 -3.62618  1.000 43.77429 ? 151 VAL D O   1 
ATOM   7412 C  CB  . VAL D 1 153 ? 13.64147  -28.13229 -3.61774  1.000 37.98761 ? 151 VAL D CB  1 
ATOM   7413 C  CG1 . VAL D 1 153 ? 15.00676  -28.34434 -2.96945  1.000 40.45963 ? 151 VAL D CG1 1 
ATOM   7414 C  CG2 . VAL D 1 153 ? 13.63541  -26.86738 -4.51480  1.000 37.45357 ? 151 VAL D CG2 1 
ATOM   7415 N  N   . GLU D 1 154 ? 12.41162  -30.93237 -2.74002  1.000 42.48621 ? 152 GLU D N   1 
ATOM   7416 C  CA  . GLU D 1 154 ? 12.50645  -32.07735 -1.85041  1.000 46.84049 ? 152 GLU D CA  1 
ATOM   7417 C  C   . GLU D 1 154 ? 12.47578  -33.38295 -2.63691  1.000 49.11116 ? 152 GLU D C   1 
ATOM   7418 O  O   . GLU D 1 154 ? 13.36350  -34.23204 -2.47752  1.000 50.55591 ? 152 GLU D O   1 
ATOM   7419 C  CB  . GLU D 1 154 ? 11.38701  -32.00628 -0.82159  1.000 44.79392 ? 152 GLU D CB  1 
ATOM   7420 C  CG  . GLU D 1 154 ? 11.83546  -31.27687 0.42541   1.000 52.72874 ? 152 GLU D CG  1 
ATOM   7421 C  CD  . GLU D 1 154 ? 13.20079  -31.76404 0.89101   1.000 60.30974 ? 152 GLU D CD  1 
ATOM   7422 O  OE1 . GLU D 1 154 ? 14.17078  -30.97636 0.82474   1.000 62.70107 ? 152 GLU D OE1 1 
ATOM   7423 O  OE2 . GLU D 1 154 ? 13.30707  -32.94393 1.30700   1.000 61.46918 ? 152 GLU D OE2 1 
ATOM   7424 N  N   . ARG D 1 155 ? 11.48483  -33.54281 -3.52600  1.000 47.87449 ? 153 ARG D N   1 
ATOM   7425 C  CA  . ARG D 1 155 ? 11.46671  -34.69427 -4.43259  1.000 45.76157 ? 153 ARG D CA  1 
ATOM   7426 C  C   . ARG D 1 155 ? 12.80836  -34.92845 -5.10617  1.000 48.41335 ? 153 ARG D C   1 
ATOM   7427 O  O   . ARG D 1 155 ? 13.12491  -36.06324 -5.48034  1.000 53.95354 ? 153 ARG D O   1 
ATOM   7428 C  CB  . ARG D 1 155 ? 10.39451  -34.51556 -5.50377  1.000 38.14524 ? 153 ARG D CB  1 
ATOM   7429 C  CG  . ARG D 1 155 ? 8.98187   -34.55435 -4.97766  1.000 36.68002 ? 153 ARG D CG  1 
ATOM   7430 C  CD  . ARG D 1 155 ? 8.04985   -34.84997 -6.11435  1.000 33.95727 ? 153 ARG D CD  1 
ATOM   7431 N  NE  . ARG D 1 155 ? 8.12150   -33.81859 -7.15061  1.000 35.76838 ? 153 ARG D NE  1 
ATOM   7432 C  CZ  . ARG D 1 155 ? 7.50182   -32.64516 -7.08676  1.000 34.84359 ? 153 ARG D CZ  1 
ATOM   7433 N  NH1 . ARG D 1 155 ? 6.76646   -32.30184 -6.03125  1.000 31.63254 ? 153 ARG D NH1 1 
ATOM   7434 N  NH2 . ARG D 1 155 ? 7.60618   -31.79884 -8.11293  1.000 34.06323 ? 153 ARG D NH2 1 
ATOM   7435 N  N   . ALA D 1 156 ? 13.60699  -33.88611 -5.28088  1.000 45.23589 ? 154 ALA D N   1 
ATOM   7436 C  CA  . ALA D 1 156 ? 14.92274  -34.05482 -5.87751  1.000 47.20196 ? 154 ALA D CA  1 
ATOM   7437 C  C   . ALA D 1 156 ? 16.00463  -34.36469 -4.84809  1.000 47.23007 ? 154 ALA D C   1 
ATOM   7438 O  O   . ALA D 1 156 ? 17.15986  -34.56230 -5.23176  1.000 51.89993 ? 154 ALA D O   1 
ATOM   7439 C  CB  . ALA D 1 156 ? 15.30263  -32.80241 -6.68370  1.000 42.55610 ? 154 ALA D CB  1 
ATOM   7440 N  N   . GLY D 1 157 ? 15.66542  -34.40284 -3.56455  1.000 49.02985 ? 155 GLY D N   1 
ATOM   7441 C  CA  . GLY D 1 157 ? 16.64902  -34.62989 -2.52499  1.000 49.60193 ? 155 GLY D CA  1 
ATOM   7442 C  C   . GLY D 1 157 ? 17.82755  -33.68267 -2.58053  1.000 51.99344 ? 155 GLY D C   1 
ATOM   7443 O  O   . GLY D 1 157 ? 18.98743  -34.10708 -2.51673  1.000 53.33288 ? 155 GLY D O   1 
ATOM   7444 N  N   . LEU D 1 158 ? 17.54224  -32.39106 -2.74033  1.000 51.06606 ? 156 LEU D N   1 
ATOM   7445 C  CA  . LEU D 1 158 ? 18.55492  -31.35950 -2.65075  1.000 48.21951 ? 156 LEU D CA  1 
ATOM   7446 C  C   . LEU D 1 158 ? 18.21161  -30.41813 -1.51472  1.000 46.29652 ? 156 LEU D C   1 
ATOM   7447 O  O   . LEU D 1 158 ? 17.06206  -30.34286 -1.06552  1.000 44.88814 ? 156 LEU D O   1 
ATOM   7448 C  CB  . LEU D 1 158 ? 18.68803  -30.57006 -3.95699  1.000 48.25113 ? 156 LEU D CB  1 
ATOM   7449 C  CG  . LEU D 1 158 ? 18.46219  -31.30636 -5.27387  1.000 48.09128 ? 156 LEU D CG  1 
ATOM   7450 C  CD1 . LEU D 1 158 ? 18.17692  -30.31764 -6.38145  1.000 46.42705 ? 156 LEU D CD1 1 
ATOM   7451 C  CD2 . LEU D 1 158 ? 19.69990  -32.11431 -5.60398  1.000 52.37705 ? 156 LEU D CD2 1 
ATOM   7452 N  N   . SER D 1 159 ? 19.23421  -29.69880 -1.06647  1.000 49.96045 ? 157 SER D N   1 
ATOM   7453 C  CA  . SER D 1 159 ? 19.09347  -28.61510 -0.10106  1.000 48.83839 ? 157 SER D CA  1 
ATOM   7454 C  C   . SER D 1 159 ? 19.02775  -27.27321 -0.82268  1.000 47.79154 ? 157 SER D C   1 
ATOM   7455 O  O   . SER D 1 159 ? 19.69929  -27.07246 -1.83598  1.000 46.31077 ? 157 SER D O   1 
ATOM   7456 C  CB  . SER D 1 159 ? 20.27405  -28.62512 0.86589   1.000 52.11715 ? 157 SER D CB  1 
ATOM   7457 O  OG  . SER D 1 159 ? 20.30546  -27.46310 1.65518   1.000 54.24888 ? 157 SER D OG  1 
ATOM   7458 N  N   . LEU D 1 160 ? 18.20839  -26.35861 -0.29113  1.000 47.52709 ? 158 LEU D N   1 
ATOM   7459 C  CA  . LEU D 1 160 ? 18.16531  -24.99002 -0.79798  1.000 48.06057 ? 158 LEU D CA  1 
ATOM   7460 C  C   . LEU D 1 160 ? 19.55414  -24.35697 -0.80571  1.000 48.15431 ? 158 LEU D C   1 
ATOM   7461 O  O   . LEU D 1 160 ? 19.92724  -23.66274 -1.76246  1.000 46.29219 ? 158 LEU D O   1 
ATOM   7462 C  CB  . LEU D 1 160 ? 17.18953  -24.17857 0.05150   1.000 49.34591 ? 158 LEU D CB  1 
ATOM   7463 C  CG  . LEU D 1 160 ? 16.31837  -23.06544 -0.52002  1.000 50.18659 ? 158 LEU D CG  1 
ATOM   7464 C  CD1 . LEU D 1 160 ? 15.56826  -23.54354 -1.72986  1.000 53.56405 ? 158 LEU D CD1 1 
ATOM   7465 C  CD2 . LEU D 1 160 ? 15.31287  -22.69417 0.54907   1.000 47.69928 ? 158 LEU D CD2 1 
ATOM   7466 N  N   . GLN D 1 161 ? 20.34812  -24.61086 0.23667   1.000 44.08535 ? 159 GLN D N   1 
ATOM   7467 C  CA  . GLN D 1 161 ? 21.72237  -24.11879 0.25393   1.000 46.39503 ? 159 GLN D CA  1 
ATOM   7468 C  C   . GLN D 1 161 ? 22.53943  -24.67426 -0.91559  1.000 47.40043 ? 159 GLN D C   1 
ATOM   7469 O  O   . GLN D 1 161 ? 23.38540  -23.96776 -1.48353  1.000 49.78591 ? 159 GLN D O   1 
ATOM   7470 C  CB  . GLN D 1 161 ? 22.36255  -24.46949 1.59181   1.000 48.03227 ? 159 GLN D CB  1 
ATOM   7471 C  CG  . GLN D 1 161 ? 21.76950  -23.66349 2.73926   1.000 44.30245 ? 159 GLN D CG  1 
ATOM   7472 C  CD  . GLN D 1 161 ? 21.99867  -22.16086 2.56344   1.000 48.52721 ? 159 GLN D CD  1 
ATOM   7473 O  OE1 . GLN D 1 161 ? 23.11755  -21.72375 2.27996   1.000 51.11462 ? 159 GLN D OE1 1 
ATOM   7474 N  NE2 . GLN D 1 161 ? 20.93765  -21.37302 2.70540   1.000 46.46611 ? 159 GLN D NE2 1 
ATOM   7475 N  N   . ASP D 1 162 ? 22.30232  -25.93386 -1.28796  1.000 47.74914 ? 160 ASP D N   1 
ATOM   7476 C  CA  . ASP D 1 162 ? 22.97940  -26.53026 -2.44031  1.000 48.54463 ? 160 ASP D CA  1 
ATOM   7477 C  C   . ASP D 1 162 ? 22.59691  -25.82851 -3.74098  1.000 42.01065 ? 160 ASP D C   1 
ATOM   7478 O  O   . ASP D 1 162 ? 23.45126  -25.54828 -4.58578  1.000 41.22977 ? 160 ASP D O   1 
ATOM   7479 C  CB  . ASP D 1 162 ? 22.62650  -28.01516 -2.53481  1.000 47.75785 ? 160 ASP D CB  1 
ATOM   7480 C  CG  . ASP D 1 162 ? 23.51018  -28.90494 -1.66136  1.000 55.92475 ? 160 ASP D CG  1 
ATOM   7481 O  OD1 . ASP D 1 162 ? 24.37424  -28.37815 -0.92814  1.000 58.34158 ? 160 ASP D OD1 1 
ATOM   7482 O  OD2 . ASP D 1 162 ? 23.31732  -30.14336 -1.70432  1.000 56.57679 ? 160 ASP D OD2 1 
ATOM   7483 N  N   . VAL D 1 163 ? 21.30130  -25.60290 -3.93887  1.000 43.71122 ? 161 VAL D N   1 
ATOM   7484 C  CA  . VAL D 1 163 ? 20.79717  -24.93578 -5.13800  1.000 44.78059 ? 161 VAL D CA  1 
ATOM   7485 C  C   . VAL D 1 163 ? 21.37976  -23.52266 -5.25836  1.000 43.34883 ? 161 VAL D C   1 
ATOM   7486 O  O   . VAL D 1 163 ? 21.77860  -23.07863 -6.34999  1.000 38.35114 ? 161 VAL D O   1 
ATOM   7487 C  CB  . VAL D 1 163 ? 19.25616  -24.93687 -5.07981  1.000 44.75161 ? 161 VAL D CB  1 
ATOM   7488 C  CG1 . VAL D 1 163 ? 18.65628  -24.10054 -6.16323  1.000 42.10097 ? 161 VAL D CG1 1 
ATOM   7489 C  CG2 . VAL D 1 163 ? 18.70482  -26.38746 -5.10693  1.000 42.58507 ? 161 VAL D CG2 1 
ATOM   7490 N  N   . ILE D 1 164 ? 21.46510  -22.80533 -4.13562  1.000 41.72721 ? 162 ILE D N   1 
ATOM   7491 C  CA  . ILE D 1 164 ? 22.08989  -21.48131 -4.14092  1.000 42.22156 ? 162 ILE D CA  1 
ATOM   7492 C  C   . ILE D 1 164 ? 23.55488  -21.58837 -4.54958  1.000 43.12727 ? 162 ILE D C   1 
ATOM   7493 O  O   . ILE D 1 164 ? 24.06471  -20.78611 -5.34204  1.000 40.69927 ? 162 ILE D O   1 
ATOM   7494 C  CB  . ILE D 1 164 ? 21.95470  -20.81220 -2.75967  1.000 40.88624 ? 162 ILE D CB  1 
ATOM   7495 C  CG1 . ILE D 1 164 ? 20.54265  -20.26091 -2.55207  1.000 41.16804 ? 162 ILE D CG1 1 
ATOM   7496 C  CG2 . ILE D 1 164 ? 22.98550  -19.67790 -2.61189  1.000 43.85642 ? 162 ILE D CG2 1 
ATOM   7497 C  CD1 . ILE D 1 164 ? 20.11621  -20.19766 -1.09512  1.000 42.41420 ? 162 ILE D CD1 1 
ATOM   7498 N  N   . ALA D 1 165 ? 24.26211  -22.58118 -4.00543  1.000 43.38123 ? 163 ALA D N   1 
ATOM   7499 C  CA  . ALA D 1 165 ? 25.69195  -22.67820 -4.27200  1.000 42.86971 ? 163 ALA D CA  1 
ATOM   7500 C  C   . ALA D 1 165 ? 25.96603  -22.91861 -5.74692  1.000 42.91846 ? 163 ALA D C   1 
ATOM   7501 O  O   . ALA D 1 165 ? 27.02884  -22.54033 -6.25473  1.000 46.56096 ? 163 ALA D O   1 
ATOM   7502 C  CB  . ALA D 1 165 ? 26.29996  -23.81205 -3.43690  1.000 48.94543 ? 163 ALA D CB  1 
ATOM   7503 N  N   . GLN D 1 166 ? 25.02603  -23.54969 -6.44782  1.000 41.91025 ? 164 GLN D N   1 
ATOM   7504 C  CA  . GLN D 1 166 ? 25.25151  -23.96831 -7.82570  1.000 43.40913 ? 164 GLN D CA  1 
ATOM   7505 C  C   . GLN D 1 166 ? 25.17560  -22.81532 -8.81851  1.000 40.35306 ? 164 GLN D C   1 
ATOM   7506 O  O   . GLN D 1 166 ? 25.55162  -22.98936 -9.98332  1.000 39.88116 ? 164 GLN D O   1 
ATOM   7507 C  CB  . GLN D 1 166 ? 24.23169  -25.04351 -8.20197  1.000 40.76968 ? 164 GLN D CB  1 
ATOM   7508 C  CG  . GLN D 1 166 ? 24.59669  -26.39978 -7.66842  1.000 46.07232 ? 164 GLN D CG  1 
ATOM   7509 C  CD  . GLN D 1 166 ? 23.59844  -27.45971 -8.06601  1.000 46.32438 ? 164 GLN D CD  1 
ATOM   7510 O  OE1 . GLN D 1 166 ? 23.30202  -27.63574 -9.24945  1.000 45.15881 ? 164 GLN D OE1 1 
ATOM   7511 N  NE2 . GLN D 1 166 ? 23.08138  -28.18571 -7.07793  1.000 47.22341 ? 164 GLN D NE2 1 
ATOM   7512 N  N   . GLN D 1 167 ? 24.68561  -21.65370 -8.39168  1.000 40.11207 ? 165 GLN D N   1 
ATOM   7513 C  CA  . GLN D 1 167 ? 24.70308  -20.47433 -9.24658  1.000 38.07259 ? 165 GLN D CA  1 
ATOM   7514 C  C   . GLN D 1 167 ? 26.11780  -19.97020 -9.49522  1.000 39.47329 ? 165 GLN D C   1 
ATOM   7515 O  O   . GLN D 1 167 ? 26.35555  -19.28739 -10.49600 1.000 39.77396 ? 165 GLN D O   1 
ATOM   7516 C  CB  . GLN D 1 167 ? 23.85412  -19.37095 -8.61093  1.000 39.79064 ? 165 GLN D CB  1 
ATOM   7517 C  CG  . GLN D 1 167 ? 23.41912  -18.26615 -9.58534  1.000 37.38469 ? 165 GLN D CG  1 
ATOM   7518 C  CD  . GLN D 1 167 ? 22.79109  -17.09928 -8.87598  1.000 39.87588 ? 165 GLN D CD  1 
ATOM   7519 O  OE1 . GLN D 1 167 ? 22.49205  -17.17343 -7.68441  1.000 41.59859 ? 165 GLN D OE1 1 
ATOM   7520 N  NE2 . GLN D 1 167 ? 22.56885  -16.00821 -9.60497  1.000 35.40895 ? 165 GLN D NE2 1 
ATOM   7521 N  N   . ASP D 1 168 ? 27.05193  -20.27473 -8.60090  1.000 41.79655 ? 166 ASP D N   1 
ATOM   7522 C  CA  . ASP D 1 168 ? 28.43142  -19.80075 -8.68685  1.000 40.88744 ? 166 ASP D CA  1 
ATOM   7523 C  C   . ASP D 1 168 ? 29.25447  -20.75784 -9.55111  1.000 44.41608 ? 166 ASP D C   1 
ATOM   7524 O  O   . ASP D 1 168 ? 29.47123  -21.90839 -9.17251  1.000 43.66269 ? 166 ASP D O   1 
ATOM   7525 C  CB  . ASP D 1 168 ? 29.01490  -19.69311 -7.27687  1.000 42.14798 ? 166 ASP D CB  1 
ATOM   7526 C  CG  . ASP D 1 168 ? 30.45660  -19.20301 -7.24713  1.000 42.84505 ? 166 ASP D CG  1 
ATOM   7527 O  OD1 . ASP D 1 168 ? 31.09445  -18.98618 -8.30701  1.000 40.03190 ? 166 ASP D OD1 1 
ATOM   7528 O  OD2 . ASP D 1 168 ? 30.96250  -19.04360 -6.11598  1.000 45.03957 ? 166 ASP D OD2 1 
ATOM   7529 N  N   . ASP D 1 169 ? 29.74627  -20.26141 -10.68796 1.000 43.12747 ? 167 ASP D N   1 
ATOM   7530 C  CA  . ASP D 1 169 ? 30.60017  -21.05934 -11.55615 1.000 44.02888 ? 167 ASP D CA  1 
ATOM   7531 C  C   . ASP D 1 169 ? 31.81461  -21.61199 -10.81939 1.000 47.11123 ? 167 ASP D C   1 
ATOM   7532 O  O   . ASP D 1 169 ? 32.32968  -22.66901 -11.19366 1.000 51.11239 ? 167 ASP D O   1 
ATOM   7533 C  CB  . ASP D 1 169 ? 31.08039  -20.21601 -12.74361 1.000 39.98309 ? 167 ASP D CB  1 
ATOM   7534 C  CG  . ASP D 1 169 ? 30.05993  -20.13245 -13.87395 1.000 40.05698 ? 167 ASP D CG  1 
ATOM   7535 O  OD1 . ASP D 1 169 ? 28.94261  -20.66843 -13.73076 1.000 38.49964 ? 167 ASP D OD1 1 
ATOM   7536 O  OD2 . ASP D 1 169 ? 30.37580  -19.47912 -14.90529 1.000 42.78760 ? 167 ASP D OD2 1 
ATOM   7537 N  N   . GLY D 1 170 ? 32.31666  -20.89928 -9.81145  1.000 48.14166 ? 168 GLY D N   1 
ATOM   7538 C  CA  . GLY D 1 170 ? 33.46400  -21.35843 -9.04889  1.000 49.86652 ? 168 GLY D CA  1 
ATOM   7539 C  C   . GLY D 1 170 ? 33.18404  -22.44475 -8.02700  1.000 50.58896 ? 168 GLY D C   1 
ATOM   7540 O  O   . GLY D 1 170 ? 34.10291  -22.93129 -7.36047  1.000 52.80225 ? 168 GLY D O   1 
ATOM   7541 N  N   . TYR D 1 171 ? 31.92967  -22.84514 -7.89070  1.000 46.38472 ? 169 TYR D N   1 
ATOM   7542 C  CA  . TYR D 1 171 ? 31.53820  -23.80945 -6.87874  1.000 51.92562 ? 169 TYR D CA  1 
ATOM   7543 C  C   . TYR D 1 171 ? 31.84637  -25.21635 -7.35862  1.000 53.40939 ? 169 TYR D C   1 
ATOM   7544 O  O   . TYR D 1 171 ? 31.50620  -25.57877 -8.48847  1.000 50.96784 ? 169 TYR D O   1 
ATOM   7545 C  CB  . TYR D 1 171 ? 30.05207  -23.66043 -6.57487  1.000 52.32973 ? 169 TYR D CB  1 
ATOM   7546 C  CG  . TYR D 1 171 ? 29.44226  -24.77040 -5.74783  1.000 49.40558 ? 169 TYR D CG  1 
ATOM   7547 C  CD1 . TYR D 1 171 ? 29.82097  -24.97816 -4.42868  1.000 50.75191 ? 169 TYR D CD1 1 
ATOM   7548 C  CD2 . TYR D 1 171 ? 28.44791  -25.58295 -6.28232  1.000 51.79646 ? 169 TYR D CD2 1 
ATOM   7549 C  CE1 . TYR D 1 171 ? 29.23668  -25.98643 -3.66936  1.000 48.73434 ? 169 TYR D CE1 1 
ATOM   7550 C  CE2 . TYR D 1 171 ? 27.85883  -26.58403 -5.53482  1.000 51.85105 ? 169 TYR D CE2 1 
ATOM   7551 C  CZ  . TYR D 1 171 ? 28.25403  -26.78197 -4.22717  1.000 50.82253 ? 169 TYR D CZ  1 
ATOM   7552 O  OH  . TYR D 1 171 ? 27.66744  -27.78987 -3.49164  1.000 54.05690 ? 169 TYR D OH  1 
ATOM   7553 N  N   . ASP D 1 172 ? 32.47864  -26.00787 -6.48730  1.000 57.07957 ? 170 ASP D N   1 
ATOM   7554 C  CA  . ASP D 1 172 ? 33.04179  -27.30463 -6.84346  1.000 57.52448 ? 170 ASP D CA  1 
ATOM   7555 C  C   . ASP D 1 172 ? 32.12601  -28.47793 -6.53994  1.000 57.76924 ? 170 ASP D C   1 
ATOM   7556 O  O   . ASP D 1 172 ? 32.45801  -29.60640 -6.91771  1.000 55.50379 ? 170 ASP D O   1 
ATOM   7557 C  CB  . ASP D 1 172 ? 34.36043  -27.52983 -6.09481  1.000 60.48198 ? 170 ASP D CB  1 
ATOM   7558 C  CG  . ASP D 1 172 ? 35.51325  -26.83938 -6.75236  1.000 67.32199 ? 170 ASP D CG  1 
ATOM   7559 O  OD1 . ASP D 1 172 ? 35.53723  -26.80608 -7.99855  1.000 68.44171 ? 170 ASP D OD1 1 
ATOM   7560 O  OD2 . ASP D 1 172 ? 36.38884  -26.31558 -6.02905  1.000 75.30215 ? 170 ASP D OD2 1 
ATOM   7561 N  N   . GLY D 1 173 ? 31.00711  -28.25088 -5.85688  1.000 57.53804 ? 171 GLY D N   1 
ATOM   7562 C  CA  . GLY D 1 173 ? 30.16963  -29.32327 -5.36910  1.000 54.52099 ? 171 GLY D CA  1 
ATOM   7563 C  C   . GLY D 1 173 ? 29.49987  -30.12037 -6.46792  1.000 56.24579 ? 171 GLY D C   1 
ATOM   7564 O  O   . GLY D 1 173 ? 29.56428  -29.77386 -7.65233  1.000 54.91841 ? 171 GLY D O   1 
ATOM   7565 N  N   . PRO D 1 174 ? 28.84720  -31.21923 -6.09322  1.000 58.13718 ? 172 PRO D N   1 
ATOM   7566 C  CA  . PRO D 1 174 ? 28.13666  -32.01971 -7.09622  1.000 57.76600 ? 172 PRO D CA  1 
ATOM   7567 C  C   . PRO D 1 174 ? 27.02824  -31.20929 -7.75923  1.000 57.57635 ? 172 PRO D C   1 
ATOM   7568 O  O   . PRO D 1 174 ? 26.35625  -30.38953 -7.12397  1.000 54.93701 ? 172 PRO D O   1 
ATOM   7569 C  CB  . PRO D 1 174 ? 27.57545  -33.19872 -6.29020  1.000 53.90642 ? 172 PRO D CB  1 
ATOM   7570 C  CG  . PRO D 1 174 ? 27.63977  -32.77527 -4.86239  1.000 55.08172 ? 172 PRO D CG  1 
ATOM   7571 C  CD  . PRO D 1 174 ? 28.73926  -31.78210 -4.73457  1.000 56.97472 ? 172 PRO D CD  1 
ATOM   7572 N  N   . ARG D 1 175 ? 26.86190  -31.43747 -9.05929  1.000 56.17669 ? 173 ARG D N   1 
ATOM   7573 C  CA  . ARG D 1 175 ? 25.79941  -30.82918 -9.83955  1.000 54.29438 ? 173 ARG D CA  1 
ATOM   7574 C  C   . ARG D 1 175 ? 25.09958  -31.89581 -10.66102 1.000 53.74854 ? 173 ARG D C   1 
ATOM   7575 O  O   . ARG D 1 175 ? 25.66808  -32.94441 -10.97077 1.000 57.98274 ? 173 ARG D O   1 
ATOM   7576 C  CB  . ARG D 1 175 ? 26.32641  -29.76005 -10.78894 1.000 48.52143 ? 173 ARG D CB  1 
ATOM   7577 C  CG  . ARG D 1 175 ? 27.16954  -28.71404 -10.14376 1.000 49.82329 ? 173 ARG D CG  1 
ATOM   7578 C  CD  . ARG D 1 175 ? 27.48485  -27.63899 -11.15162 1.000 47.53769 ? 173 ARG D CD  1 
ATOM   7579 N  NE  . ARG D 1 175 ? 28.44357  -26.67235 -10.63804 1.000 47.72914 ? 173 ARG D NE  1 
ATOM   7580 C  CZ  . ARG D 1 175 ? 28.34812  -25.37103 -10.86679 1.000 44.54977 ? 173 ARG D CZ  1 
ATOM   7581 N  NH1 . ARG D 1 175 ? 27.35305  -24.87955 -11.57941 1.000 41.28075 ? 173 ARG D NH1 1 
ATOM   7582 N  NH2 . ARG D 1 175 ? 29.26874  -24.55019 -10.36706 1.000 40.51041 ? 173 ARG D NH2 1 
ATOM   7583 N  N   . SER D 1 176 ? 23.86045  -31.59877 -11.03484 1.000 50.63139 ? 174 SER D N   1 
ATOM   7584 C  CA  . SER D 1 176 ? 23.12972  -32.42595 -11.98238 1.000 50.27130 ? 174 SER D CA  1 
ATOM   7585 C  C   . SER D 1 176 ? 22.24768  -31.52966 -12.84068 1.000 52.56364 ? 174 SER D C   1 
ATOM   7586 O  O   . SER D 1 176 ? 22.06110  -30.33982 -12.54725 1.000 46.73482 ? 174 SER D O   1 
ATOM   7587 C  CB  . SER D 1 176 ? 22.29923  -33.48520 -11.26171 1.000 50.02860 ? 174 SER D CB  1 
ATOM   7588 O  OG  . SER D 1 176 ? 21.28270  -32.89802 -10.47447 1.000 47.76174 ? 174 SER D OG  1 
ATOM   7589 N  N   . GLY D 1 177 ? 21.71525  -32.11053 -13.92166 1.000 48.80989 ? 175 GLY D N   1 
ATOM   7590 C  CA  . GLY D 1 177 ? 20.83055  -31.34678 -14.78582 1.000 47.66605 ? 175 GLY D CA  1 
ATOM   7591 C  C   . GLY D 1 177 ? 19.60913  -30.83275 -14.05031 1.000 46.13679 ? 175 GLY D C   1 
ATOM   7592 O  O   . GLY D 1 177 ? 19.09960  -29.75055 -14.35325 1.000 42.58806 ? 175 GLY D O   1 
ATOM   7593 N  N   . GLY D 1 178 ? 19.14126  -31.58326 -13.06595 1.000 42.04116 ? 176 GLY D N   1 
ATOM   7594 C  CA  . GLY D 1 178 ? 17.94925  -31.23873 -12.33086 1.000 39.85428 ? 176 GLY D CA  1 
ATOM   7595 C  C   . GLY D 1 178 ? 18.22233  -30.20103 -11.26263 1.000 42.79279 ? 176 GLY D C   1 
ATOM   7596 O  O   . GLY D 1 178 ? 17.38734  -29.33014 -11.01373 1.000 38.42103 ? 176 GLY D O   1 
ATOM   7597 N  N   . SER D 1 179 ? 19.39406  -30.27298 -10.62912 1.000 41.50015 ? 177 SER D N   1 
ATOM   7598 C  CA  . SER D 1 179 ? 19.69795  -29.31231 -9.57971  1.000 43.13543 ? 177 SER D CA  1 
ATOM   7599 C  C   . SER D 1 179 ? 20.00759  -27.93805 -10.16790 1.000 41.68334 ? 177 SER D C   1 
ATOM   7600 O  O   . SER D 1 179 ? 19.64354  -26.91305 -9.58840  1.000 38.25397 ? 177 SER D O   1 
ATOM   7601 C  CB  . SER D 1 179 ? 20.85985  -29.81853 -8.72730  1.000 44.26251 ? 177 SER D CB  1 
ATOM   7602 O  OG  . SER D 1 179 ? 22.05660  -29.81553 -9.46673  1.000 41.93429 ? 177 SER D OG  1 
ATOM   7603 N  N   . GLN D 1 180 ? 20.67422  -27.90030 -11.32140 1.000 40.91437 ? 178 GLN D N   1 
ATOM   7604 C  CA  . GLN D 1 180 ? 20.93324  -26.62855 -11.97002 1.000 39.24287 ? 178 GLN D CA  1 
ATOM   7605 C  C   . GLN D 1 180 ? 19.65342  -26.02642 -12.52902 1.000 38.40844 ? 178 GLN D C   1 
ATOM   7606 O  O   . GLN D 1 180 ? 19.47015  -24.80172 -12.49227 1.000 37.50496 ? 178 GLN D O   1 
ATOM   7607 C  CB  . GLN D 1 180 ? 21.99642  -26.82006 -13.04588 1.000 38.91346 ? 178 GLN D CB  1 
ATOM   7608 C  CG  . GLN D 1 180 ? 23.30228  -27.31662 -12.46323 1.000 40.79531 ? 178 GLN D CG  1 
ATOM   7609 C  CD  . GLN D 1 180 ? 24.46229  -27.13908 -13.41129 1.000 41.60344 ? 178 GLN D CD  1 
ATOM   7610 O  OE1 . GLN D 1 180 ? 25.24855  -26.20327 -13.27875 1.000 39.18473 ? 178 GLN D OE1 1 
ATOM   7611 N  NE2 . GLN D 1 180 ? 24.62512  -28.08755 -14.33379 1.000 44.36329 ? 178 GLN D NE2 1 
ATOM   7612 N  N   . SER D 1 181 ? 18.75139  -26.87042 -13.02979 1.000 36.38302 ? 179 SER D N   1 
ATOM   7613 C  CA  . SER D 1 181 ? 17.43478  -26.40866 -13.45343 1.000 36.42140 ? 179 SER D CA  1 
ATOM   7614 C  C   . SER D 1 181 ? 16.66234  -25.80134 -12.29253 1.000 36.12867 ? 179 SER D C   1 
ATOM   7615 O  O   . SER D 1 181 ? 16.04772  -24.74324 -12.42714 1.000 35.30110 ? 179 SER D O   1 
ATOM   7616 C  CB  . SER D 1 181 ? 16.65298  -27.57193 -14.05694 1.000 36.21531 ? 179 SER D CB  1 
ATOM   7617 O  OG  . SER D 1 181 ? 17.22608  -27.92849 -15.29599 1.000 34.45794 ? 179 SER D OG  1 
ATOM   7618 N  N   . LEU D 1 182 ? 16.63290  -26.49188 -11.15390 1.000 36.26344 ? 180 LEU D N   1 
ATOM   7619 C  CA  . LEU D 1 182 ? 15.97816  -25.93385 -9.98092  1.000 34.12355 ? 180 LEU D CA  1 
ATOM   7620 C  C   . LEU D 1 182 ? 16.68224  -24.68001 -9.48913  1.000 34.63325 ? 180 LEU D C   1 
ATOM   7621 O  O   . LEU D 1 182 ? 16.05686  -23.85075 -8.81283  1.000 36.89533 ? 180 LEU D O   1 
ATOM   7622 C  CB  . LEU D 1 182 ? 15.92136  -26.99247 -8.87204  1.000 34.67764 ? 180 LEU D CB  1 
ATOM   7623 C  CG  . LEU D 1 182 ? 14.82082  -28.02004 -9.11963  1.000 38.37385 ? 180 LEU D CG  1 
ATOM   7624 C  CD1 . LEU D 1 182 ? 14.92499  -29.26621 -8.18997  1.000 38.43993 ? 180 LEU D CD1 1 
ATOM   7625 C  CD2 . LEU D 1 182 ? 13.45722  -27.35223 -8.97989  1.000 34.65487 ? 180 LEU D CD2 1 
ATOM   7626 N  N   . ALA D 1 183 ? 17.96690  -24.52681 -9.81486  1.000 33.48965 ? 181 ALA D N   1 
ATOM   7627 C  CA  . ALA D 1 183 ? 18.68266  -23.31063 -9.46042  1.000 35.77088 ? 181 ALA D CA  1 
ATOM   7628 C  C   . ALA D 1 183 ? 18.25461  -22.13150 -10.34140 1.000 37.05471 ? 181 ALA D C   1 
ATOM   7629 O  O   . ALA D 1 183 ? 18.10447  -21.00292 -9.85584  1.000 34.96718 ? 181 ALA D O   1 
ATOM   7630 C  CB  . ALA D 1 183 ? 20.18601  -23.57795 -9.55223  1.000 34.63427 ? 181 ALA D CB  1 
ATOM   7631 N  N   . LEU D 1 184 ? 18.04546  -22.36831 -11.63724 1.000 37.31463 ? 182 LEU D N   1 
ATOM   7632 C  CA  . LEU D 1 184 ? 17.50216  -21.31956 -12.50073 1.000 34.11470 ? 182 LEU D CA  1 
ATOM   7633 C  C   . LEU D 1 184 ? 16.08986  -20.93425 -12.07761 1.000 35.82161 ? 182 LEU D C   1 
ATOM   7634 O  O   . LEU D 1 184 ? 15.67957  -19.77308 -12.24656 1.000 35.27450 ? 182 LEU D O   1 
ATOM   7635 C  CB  . LEU D 1 184 ? 17.48584  -21.79922 -13.95686 1.000 36.05366 ? 182 LEU D CB  1 
ATOM   7636 C  CG  . LEU D 1 184 ? 18.80942  -22.11583 -14.64529 1.000 36.08906 ? 182 LEU D CG  1 
ATOM   7637 C  CD1 . LEU D 1 184 ? 18.59261  -22.57692 -16.09038 1.000 32.91240 ? 182 LEU D CD1 1 
ATOM   7638 C  CD2 . LEU D 1 184 ? 19.73062  -20.89819 -14.59284 1.000 35.99946 ? 182 LEU D CD2 1 
ATOM   7639 N  N   . VAL D 1 185 ? 15.32419  -21.89048 -11.55427 1.000 33.58870 ? 183 VAL D N   1 
ATOM   7640 C  CA  . VAL D 1 185 ? 13.98366  -21.57615 -11.06420 1.000 34.04727 ? 183 VAL D CA  1 
ATOM   7641 C  C   . VAL D 1 185 ? 14.07804  -20.70271 -9.82080  1.000 35.26846 ? 183 VAL D C   1 
ATOM   7642 O  O   . VAL D 1 185 ? 13.36839  -19.68844 -9.70268  1.000 36.78020 ? 183 VAL D O   1 
ATOM   7643 C  CB  . VAL D 1 185 ? 13.17520  -22.86129 -10.78835 1.000 35.53732 ? 183 VAL D CB  1 
ATOM   7644 C  CG1 . VAL D 1 185 ? 11.82651  -22.52164 -10.12993 1.000 35.64246 ? 183 VAL D CG1 1 
ATOM   7645 C  CG2 . VAL D 1 185 ? 12.98886  -23.70103 -12.06287 1.000 31.63133 ? 183 VAL D CG2 1 
ATOM   7646 N  N   . ARG D 1 186 ? 14.97207  -21.05851 -8.88692  1.000 32.24175 ? 184 ARG D N   1 
ATOM   7647 C  CA  . ARG D 1 186 ? 15.15219  -20.24143 -7.68854  1.000 34.56745 ? 184 ARG D CA  1 
ATOM   7648 C  C   . ARG D 1 186 ? 15.53359  -18.81459 -8.06004  1.000 35.70307 ? 184 ARG D C   1 
ATOM   7649 O  O   . ARG D 1 186 ? 14.97953  -17.85134 -7.51161  1.000 34.69057 ? 184 ARG D O   1 
ATOM   7650 C  CB  . ARG D 1 186 ? 16.22627  -20.82562 -6.76559  1.000 35.81346 ? 184 ARG D CB  1 
ATOM   7651 C  CG  . ARG D 1 186 ? 16.34903  -20.00272 -5.46415  1.000 38.50516 ? 184 ARG D CG  1 
ATOM   7652 C  CD  . ARG D 1 186 ? 17.71374  -20.08841 -4.78559  1.000 39.87808 ? 184 ARG D CD  1 
ATOM   7653 N  NE  . ARG D 1 186 ? 18.79921  -19.58441 -5.61502  1.000 43.66221 ? 184 ARG D NE  1 
ATOM   7654 C  CZ  . ARG D 1 186 ? 19.47734  -18.45886 -5.40400  1.000 41.05013 ? 184 ARG D CZ  1 
ATOM   7655 N  NH1 . ARG D 1 186 ? 19.20815  -17.66405 -4.38278  1.000 42.02374 ? 184 ARG D NH1 1 
ATOM   7656 N  NH2 . ARG D 1 186 ? 20.46277  -18.12935 -6.23678  1.000 37.62110 ? 184 ARG D NH2 1 
ATOM   7657 N  N   . GLU D 1 187 ? 16.47869  -18.66753 -8.99888  1.000 33.86484 ? 185 GLU D N   1 
ATOM   7658 C  CA  . GLU D 1 187 ? 16.93866  -17.34613 -9.39361  1.000 36.84309 ? 185 GLU D CA  1 
ATOM   7659 C  C   . GLU D 1 187 ? 15.80732  -16.53605 -10.01795 1.000 35.24790 ? 185 GLU D C   1 
ATOM   7660 O  O   . GLU D 1 187 ? 15.64411  -15.35459 -9.69875  1.000 34.56628 ? 185 GLU D O   1 
ATOM   7661 C  CB  . GLU D 1 187 ? 18.15049  -17.47909 -10.31445 1.000 35.24572 ? 185 GLU D CB  1 
ATOM   7662 C  CG  . GLU D 1 187 ? 19.31124  -18.17824 -9.59563  1.000 35.13560 ? 185 GLU D CG  1 
ATOM   7663 C  CD  . GLU D 1 187 ? 20.23462  -18.98710 -10.51238 1.000 38.96291 ? 185 GLU D CD  1 
ATOM   7664 O  OE1 . GLU D 1 187 ? 20.39432  -18.63732 -11.70497 1.000 35.37859 ? 185 GLU D OE1 1 
ATOM   7665 O  OE2 . GLU D 1 187 ? 20.78977  -20.00727 -10.03014 1.000 36.72699 ? 185 GLU D OE2 1 
ATOM   7666 N  N   . ALA D 1 188 ? 14.97069  -17.17393 -10.83904 1.000 33.43197 ? 186 ALA D N   1 
ATOM   7667 C  CA  . ALA D 1 188 ? 13.83153  -16.49010 -11.44510 1.000 33.29721 ? 186 ALA D CA  1 
ATOM   7668 C  C   . ALA D 1 188 ? 12.76772  -16.11167 -10.42182 1.000 33.41180 ? 186 ALA D C   1 
ATOM   7669 O  O   . ALA D 1 188 ? 12.13348  -15.04869 -10.54994 1.000 29.69826 ? 186 ALA D O   1 
ATOM   7670 C  CB  . ALA D 1 188 ? 13.20873  -17.35278 -12.53360 1.000 33.69332 ? 186 ALA D CB  1 
ATOM   7671 N  N   . MET D 1 189 ? 12.50200  -16.96320 -9.42742  1.000 30.53206 ? 187 MET D N   1 
ATOM   7672 C  CA  . MET D 1 189 ? 11.54334  -16.51214 -8.41999  1.000 31.89246 ? 187 MET D CA  1 
ATOM   7673 C  C   . MET D 1 189 ? 12.11600  -15.43892 -7.50834  1.000 30.48558 ? 187 MET D C   1 
ATOM   7674 O  O   . MET D 1 189 ? 11.36018  -14.58860 -7.03353  1.000 35.63101 ? 187 MET D O   1 
ATOM   7675 C  CB  . MET D 1 189 ? 10.88606  -17.65810 -7.59687  1.000 31.29127 ? 187 MET D CB  1 
ATOM   7676 C  CG  . MET D 1 189 ? 10.70687  -19.03304 -8.20045  1.000 30.46948 ? 187 MET D CG  1 
ATOM   7677 S  SD  . MET D 1 189 ? 10.63855  -20.45159 -7.05041  1.000 33.03155 ? 187 MET D SD  1 
ATOM   7678 C  CE  . MET D 1 189 ? 8.99607   -20.20485 -6.39148  1.000 37.40709 ? 187 MET D CE  1 
ATOM   7679 N  N   . LEU D 1 190 ? 13.43034  -15.39262 -7.30110  1.000 30.65572 ? 188 LEU D N   1 
ATOM   7680 C  CA  . LEU D 1 190 ? 13.96602  -14.26893 -6.54269  1.000 31.52218 ? 188 LEU D CA  1 
ATOM   7681 C  C   . LEU D 1 190 ? 13.85334  -12.96721 -7.33899  1.000 34.88821 ? 188 LEU D C   1 
ATOM   7682 O  O   . LEU D 1 190 ? 13.52565  -11.91873 -6.77459  1.000 33.03593 ? 188 LEU D O   1 
ATOM   7683 C  CB  . LEU D 1 190 ? 15.41327  -14.55202 -6.12380  1.000 34.44001 ? 188 LEU D CB  1 
ATOM   7684 C  CG  . LEU D 1 190 ? 16.27218  -13.55247 -5.31780  1.000 36.36273 ? 188 LEU D CG  1 
ATOM   7685 C  CD1 . LEU D 1 190 ? 17.58594  -14.21320 -4.94506  1.000 43.37628 ? 188 LEU D CD1 1 
ATOM   7686 C  CD2 . LEU D 1 190 ? 16.63478  -12.31016 -6.10512  1.000 39.88922 ? 188 LEU D CD2 1 
ATOM   7687 N  N   . ARG D 1 191 ? 14.15302  -13.00555 -8.64452  1.000 32.20335 ? 189 ARG D N   1 
ATOM   7688 C  CA  . ARG D 1 191 ? 13.99986  -11.80312 -9.45679  1.000 33.52643 ? 189 ARG D CA  1 
ATOM   7689 C  C   . ARG D 1 191 ? 12.56176  -11.30127 -9.42280  1.000 35.39249 ? 189 ARG D C   1 
ATOM   7690 O  O   . ARG D 1 191 ? 12.32635  -10.09256 -9.31690  1.000 36.57879 ? 189 ARG D O   1 
ATOM   7691 C  CB  . ARG D 1 191 ? 14.46055  -12.06280 -10.90077 1.000 33.31207 ? 189 ARG D CB  1 
ATOM   7692 C  CG  . ARG D 1 191 ? 15.99281  -12.07362 -11.06352 1.000 33.99050 ? 189 ARG D CG  1 
ATOM   7693 C  CD  . ARG D 1 191 ? 16.47949  -12.18348 -12.54630 1.000 32.01601 ? 189 ARG D CD  1 
ATOM   7694 N  NE  . ARG D 1 191 ? 15.87172  -13.30395 -13.26870 1.000 36.92962 ? 189 ARG D NE  1 
ATOM   7695 C  CZ  . ARG D 1 191 ? 16.40157  -14.51843 -13.35750 1.000 38.07093 ? 189 ARG D CZ  1 
ATOM   7696 N  NH1 . ARG D 1 191 ? 17.56237  -14.80591 -12.78820 1.000 40.13283 ? 189 ARG D NH1 1 
ATOM   7697 N  NH2 . ARG D 1 191 ? 15.75774  -15.46570 -14.04385 1.000 33.01790 ? 189 ARG D NH2 1 
ATOM   7698 N  N   . LEU D 1 192 ? 11.58372  -12.21188 -9.49629  1.000 31.93459 ? 190 LEU D N   1 
ATOM   7699 C  CA  . LEU D 1 192 ? 10.18623  -11.79986 -9.40991  1.000 32.73750 ? 190 LEU D CA  1 
ATOM   7700 C  C   . LEU D 1 192 ? 9.89647   -11.11417 -8.07933  1.000 36.40177 ? 190 LEU D C   1 
ATOM   7701 O  O   . LEU D 1 192 ? 9.23298   -10.06637 -8.02148  1.000 32.24740 ? 190 LEU D O   1 
ATOM   7702 C  CB  . LEU D 1 192 ? 9.28273   -13.02319 -9.57888  1.000 25.86554 ? 190 LEU D CB  1 
ATOM   7703 C  CG  . LEU D 1 192 ? 7.78469   -12.82917 -9.36106  1.000 29.39253 ? 190 LEU D CG  1 
ATOM   7704 C  CD1 . LEU D 1 192 ? 7.23284   -11.70573 -10.23460 1.000 33.66650 ? 190 LEU D CD1 1 
ATOM   7705 C  CD2 . LEU D 1 192 ? 7.05906   -14.14913 -9.65219  1.000 33.95771 ? 190 LEU D CD2 1 
ATOM   7706 N  N   . ASP D 1 193 ? 10.36928  -11.70629 -6.99098  1.000 34.31214 ? 191 ASP D N   1 
ATOM   7707 C  CA  . ASP D 1 193 ? 10.04633  -11.17991 -5.66665  1.000 34.65960 ? 191 ASP D CA  1 
ATOM   7708 C  C   . ASP D 1 193 ? 10.74800  -9.84477  -5.40994  1.000 35.78424 ? 191 ASP D C   1 
ATOM   7709 O  O   . ASP D 1 193 ? 10.17614  -8.94411  -4.77690  1.000 35.06158 ? 191 ASP D O   1 
ATOM   7710 C  CB  . ASP D 1 193 ? 10.41066  -12.24030 -4.62264  1.000 34.38857 ? 191 ASP D CB  1 
ATOM   7711 C  CG  . ASP D 1 193 ? 9.60803   -12.11597 -3.33996  1.000 39.41233 ? 191 ASP D CG  1 
ATOM   7712 O  OD1 . ASP D 1 193 ? 8.76056   -11.19527 -3.21759  1.000 40.58844 ? 191 ASP D OD1 1 
ATOM   7713 O  OD2 . ASP D 1 193 ? 9.80836   -12.96705 -2.45199  1.000 36.84980 ? 191 ASP D OD2 1 
ATOM   7714 N  N   . GLY D 1 194 ? 11.97987  -9.69137  -5.89961  1.000 34.01553 ? 192 GLY D N   1 
ATOM   7715 C  CA  . GLY D 1 194 ? 12.64682  -8.40497  -5.81637  1.000 38.09541 ? 192 GLY D CA  1 
ATOM   7716 C  C   . GLY D 1 194 ? 11.95191  -7.33936  -6.64171  1.000 38.24218 ? 192 GLY D C   1 
ATOM   7717 O  O   . GLY D 1 194 ? 11.97012  -6.15419  -6.28034  1.000 33.48334 ? 192 GLY D O   1 
ATOM   7718 N  N   . SER D 1 195 ? 11.32996  -7.74123  -7.75676  1.000 36.94186 ? 193 SER D N   1 
ATOM   7719 C  CA  . SER D 1 195 ? 10.58001  -6.78423  -8.56121  1.000 36.68052 ? 193 SER D CA  1 
ATOM   7720 C  C   . SER D 1 195 ? 9.28926   -6.38848  -7.85327  1.000 36.09075 ? 193 SER D C   1 
ATOM   7721 O  O   . SER D 1 195 ? 8.86172   -5.23955  -7.93153  1.000 33.18692 ? 193 SER D O   1 
ATOM   7722 C  CB  . SER D 1 195 ? 10.27356  -7.36553  -9.94586  1.000 34.95030 ? 193 SER D CB  1 
ATOM   7723 O  OG  . SER D 1 195 ? 9.23343   -6.62762  -10.58183 1.000 30.65882 ? 193 SER D OG  1 
ATOM   7724 N  N   . VAL D 1 196 ? 8.65718   -7.31968  -7.14787  1.000 32.33950 ? 194 VAL D N   1 
ATOM   7725 C  CA  . VAL D 1 196 ? 7.44077   -6.94807  -6.42314  1.000 35.38966 ? 194 VAL D CA  1 
ATOM   7726 C  C   . VAL D 1 196 ? 7.77285   -6.13055  -5.17576  1.000 35.46176 ? 194 VAL D C   1 
ATOM   7727 O  O   . VAL D 1 196 ? 7.04283   -5.19250  -4.81723  1.000 34.09390 ? 194 VAL D O   1 
ATOM   7728 C  CB  . VAL D 1 196 ? 6.61082   -8.20362  -6.09364  1.000 31.12711 ? 194 VAL D CB  1 
ATOM   7729 C  CG1 . VAL D 1 196 ? 5.49303   -7.86576  -5.09673  1.000 29.77035 ? 194 VAL D CG1 1 
ATOM   7730 C  CG2 . VAL D 1 196 ? 6.02334   -8.74360  -7.37612  1.000 33.00838 ? 194 VAL D CG2 1 
ATOM   7731 N  N   . LEU D 1 197 ? 8.87273   -6.45821  -4.49569  1.000 34.38358 ? 195 LEU D N   1 
ATOM   7732 C  CA  . LEU D 1 197 ? 9.37583   -5.56659  -3.44953  1.000 35.64282 ? 195 LEU D CA  1 
ATOM   7733 C  C   . LEU D 1 197 ? 9.68111   -4.18851  -4.02352  1.000 34.59273 ? 195 LEU D C   1 
ATOM   7734 O  O   . LEU D 1 197 ? 9.53002   -3.17244  -3.33908  1.000 35.10526 ? 195 LEU D O   1 
ATOM   7735 C  CB  . LEU D 1 197 ? 10.63071  -6.17942  -2.82077  1.000 37.00452 ? 195 LEU D CB  1 
ATOM   7736 C  CG  . LEU D 1 197 ? 10.37715  -7.43323  -1.94816  1.000 39.79549 ? 195 LEU D CG  1 
ATOM   7737 C  CD1 . LEU D 1 197 ? 11.66048  -7.96407  -1.31942  1.000 37.92782 ? 195 LEU D CD1 1 
ATOM   7738 C  CD2 . LEU D 1 197 ? 9.36667   -7.10255  -0.84425  1.000 41.73908 ? 195 LEU D CD2 1 
ATOM   7739 N  N   . GLY D 1 198 ? 10.12763  -4.13538  -5.27781  1.000 32.75683 ? 196 GLY D N   1 
ATOM   7740 C  CA  . GLY D 1 198 ? 10.34600  -2.85645  -5.91646  1.000 31.04471 ? 196 GLY D CA  1 
ATOM   7741 C  C   . GLY D 1 198 ? 9.04887   -2.11270  -6.16413  1.000 33.16693 ? 196 GLY D C   1 
ATOM   7742 O  O   . GLY D 1 198 ? 8.97626   -0.89649  -5.97206  1.000 31.61565 ? 196 GLY D O   1 
ATOM   7743 N  N   . TRP D 1 199 ? 7.99314   -2.82746  -6.56378  1.000 30.20887 ? 197 TRP D N   1 
ATOM   7744 C  CA  . TRP D 1 199 ? 6.71544   -2.13634  -6.70462  1.000 30.57756 ? 197 TRP D CA  1 
ATOM   7745 C  C   . TRP D 1 199 ? 6.28882   -1.51711  -5.37720  1.000 34.33845 ? 197 TRP D C   1 
ATOM   7746 O  O   . TRP D 1 199 ? 5.77814   -0.38877  -5.33415  1.000 31.54309 ? 197 TRP D O   1 
ATOM   7747 C  CB  . TRP D 1 199 ? 5.62745   -3.08755  -7.19572  1.000 28.38937 ? 197 TRP D CB  1 
ATOM   7748 C  CG  . TRP D 1 199 ? 4.32319   -2.35298  -7.31180  1.000 28.40656 ? 197 TRP D CG  1 
ATOM   7749 C  CD1 . TRP D 1 199 ? 3.87774   -1.63043  -8.39787  1.000 30.74900 ? 197 TRP D CD1 1 
ATOM   7750 C  CD2 . TRP D 1 199 ? 3.34221   -2.18332  -6.28831  1.000 28.49809 ? 197 TRP D CD2 1 
ATOM   7751 N  NE1 . TRP D 1 199 ? 2.65212   -1.05292  -8.10829  1.000 31.54719 ? 197 TRP D NE1 1 
ATOM   7752 C  CE2 . TRP D 1 199 ? 2.30580   -1.38142  -6.82033  1.000 31.60844 ? 197 TRP D CE2 1 
ATOM   7753 C  CE3 . TRP D 1 199 ? 3.23254   -2.63487  -4.97114  1.000 31.97363 ? 197 TRP D CE3 1 
ATOM   7754 C  CZ2 . TRP D 1 199 ? 1.17829   -1.02126  -6.07106  1.000 29.67095 ? 197 TRP D CZ2 1 
ATOM   7755 C  CZ3 . TRP D 1 199 ? 2.11834   -2.30820  -4.24608  1.000 31.36341 ? 197 TRP D CZ3 1 
ATOM   7756 C  CH2 . TRP D 1 199 ? 1.10059   -1.48757  -4.79260  1.000 32.61352 ? 197 TRP D CH2 1 
ATOM   7757 N  N   . LYS D 1 200 ? 6.47538   -2.25428  -4.28441  1.000 29.59254 ? 198 LYS D N   1 
ATOM   7758 C  CA  . LYS D 1 200 ? 5.98971   -1.78025  -2.99324  1.000 31.53102 ? 198 LYS D CA  1 
ATOM   7759 C  C   . LYS D 1 200 ? 6.73984   -0.52971  -2.56236  1.000 33.80371 ? 198 LYS D C   1 
ATOM   7760 O  O   . LYS D 1 200 ? 6.12646   0.44005   -2.08650  1.000 34.54376 ? 198 LYS D O   1 
ATOM   7761 C  CB  . LYS D 1 200 ? 6.09950   -2.91361  -1.95808  1.000 31.68993 ? 198 LYS D CB  1 
ATOM   7762 C  CG  . LYS D 1 200 ? 5.07218   -4.01421  -2.18151  1.000 34.26412 ? 198 LYS D CG  1 
ATOM   7763 C  CD  . LYS D 1 200 ? 4.95857   -4.97298  -0.95206  1.000 44.13225 ? 198 LYS D CD  1 
ATOM   7764 C  CE  . LYS D 1 200 ? 3.60789   -5.72236  -0.89188  1.000 51.85740 ? 198 LYS D CE  1 
ATOM   7765 N  NZ  . LYS D 1 200 ? 3.12331   -6.01939  0.53013   1.000 52.81477 ? 198 LYS D NZ  1 
ATOM   7766 N  N   . GLN D 1 201 ? 8.05519   -0.50025  -2.78067  1.000 32.62295 ? 199 GLN D N   1 
ATOM   7767 C  CA  . GLN D 1 201 ? 8.82461   0.67643   -2.39297  1.000 31.57347 ? 199 GLN D CA  1 
ATOM   7768 C  C   . GLN D 1 201 ? 8.46156   1.89716   -3.24371  1.000 34.55481 ? 199 GLN D C   1 
ATOM   7769 O  O   . GLN D 1 201 ? 8.30871   3.00197   -2.71472  1.000 33.04178 ? 199 GLN D O   1 
ATOM   7770 C  CB  . GLN D 1 201 ? 10.31743  0.35735   -2.47870  1.000 32.59773 ? 199 GLN D CB  1 
ATOM   7771 C  CG  . GLN D 1 201 ? 10.77643  -0.58353  -1.36656  1.000 36.80426 ? 199 GLN D CG  1 
ATOM   7772 C  CD  . GLN D 1 201 ? 10.28101  -0.12977  0.00455   1.000 39.56587 ? 199 GLN D CD  1 
ATOM   7773 O  OE1 . GLN D 1 201 ? 10.55290  0.99659   0.43985   1.000 43.48686 ? 199 GLN D OE1 1 
ATOM   7774 N  NE2 . GLN D 1 201 ? 9.55868   -1.00131  0.68949   1.000 44.35500 ? 199 GLN D NE2 1 
ATOM   7775 N  N   . HIS D 1 202 ? 8.30329   1.71988   -4.55980  1.000 33.65819 ? 200 HIS D N   1 
ATOM   7776 C  CA  . HIS D 1 202 ? 7.93928   2.84810   -5.41632  1.000 31.90138 ? 200 HIS D CA  1 
ATOM   7777 C  C   . HIS D 1 202 ? 6.53435   3.35918   -5.09981  1.000 34.23047 ? 200 HIS D C   1 
ATOM   7778 O  O   . HIS D 1 202 ? 6.30153   4.57411   -5.08298  1.000 32.24196 ? 200 HIS D O   1 
ATOM   7779 C  CB  . HIS D 1 202 ? 8.05583   2.44463   -6.88865  1.000 32.66746 ? 200 HIS D CB  1 
ATOM   7780 C  CG  . HIS D 1 202 ? 9.46380   2.43554   -7.37981  1.000 33.52508 ? 200 HIS D CG  1 
ATOM   7781 N  ND1 . HIS D 1 202 ? 10.18181  3.59246   -7.57908  1.000 40.78985 ? 200 HIS D ND1 1 
ATOM   7782 C  CD2 . HIS D 1 202 ? 10.30076  1.41492   -7.68895  1.000 34.94302 ? 200 HIS D CD2 1 
ATOM   7783 C  CE1 . HIS D 1 202 ? 11.40129  3.28810   -7.98934  1.000 39.34867 ? 200 HIS D CE1 1 
ATOM   7784 N  NE2 . HIS D 1 202 ? 11.49624  1.97481   -8.07549  1.000 37.65987 ? 200 HIS D NE2 1 
ATOM   7785 N  N   . HIS D 1 203 ? 5.58252   2.44852   -4.84953  1.000 31.02973 ? 201 HIS D N   1 
ATOM   7786 C  CA  . HIS D 1 203 ? 4.25071   2.87210   -4.42111  1.000 33.02949 ? 201 HIS D CA  1 
ATOM   7787 C  C   . HIS D 1 203 ? 4.32899   3.68573   -3.13154  1.000 32.07950 ? 201 HIS D C   1 
ATOM   7788 O  O   . HIS D 1 203 ? 3.65885   4.72223   -2.99093  1.000 33.23275 ? 201 HIS D O   1 
ATOM   7789 C  CB  . HIS D 1 203 ? 3.35150   1.64047   -4.24471  1.000 34.09386 ? 201 HIS D CB  1 
ATOM   7790 C  CG  . HIS D 1 203 ? 2.02839   1.94846   -3.62312  1.000 30.89607 ? 201 HIS D CG  1 
ATOM   7791 N  ND1 . HIS D 1 203 ? 1.80360   1.82438   -2.26904  1.000 30.71413 ? 201 HIS D ND1 1 
ATOM   7792 C  CD2 . HIS D 1 203 ? 0.86216   2.37002   -4.16394  1.000 27.70454 ? 201 HIS D CD2 1 
ATOM   7793 C  CE1 . HIS D 1 203 ? 0.55662   2.16056   -2.00036  1.000 32.98459 ? 201 HIS D CE1 1 
ATOM   7794 N  NE2 . HIS D 1 203 ? -0.03121  2.50890   -3.12558  1.000 30.19341 ? 201 HIS D NE2 1 
ATOM   7795 N  N   . LEU D 1 204 ? 5.19670   3.26283   -2.20948  1.000 34.34370 ? 202 LEU D N   1 
ATOM   7796 C  CA  . LEU D 1 204 ? 5.42871   3.99667   -0.96193  1.000 34.93517 ? 202 LEU D CA  1 
ATOM   7797 C  C   . LEU D 1 204 ? 6.00713   5.38135   -1.22648  1.000 38.73307 ? 202 LEU D C   1 
ATOM   7798 O  O   . LEU D 1 204 ? 5.61829   6.36519   -0.58246  1.000 37.84137 ? 202 LEU D O   1 
ATOM   7799 C  CB  . LEU D 1 204 ? 6.38990   3.19765   -0.07283  1.000 39.89933 ? 202 LEU D CB  1 
ATOM   7800 C  CG  . LEU D 1 204 ? 6.50522   3.56731   1.41142   1.000 45.42837 ? 202 LEU D CG  1 
ATOM   7801 C  CD1 . LEU D 1 204 ? 5.11145   3.74875   1.99882   1.000 44.19978 ? 202 LEU D CD1 1 
ATOM   7802 C  CD2 . LEU D 1 204 ? 7.29447   2.50715   2.20013   1.000 43.97686 ? 202 LEU D CD2 1 
ATOM   7803 N  N   . ILE D 1 205 ? 6.99498   5.46550   -2.12410  1.000 35.08531 ? 203 ILE D N   1 
ATOM   7804 C  CA  . ILE D 1 205 ? 7.60717   6.75587   -2.42184  1.000 34.22263 ? 203 ILE D CA  1 
ATOM   7805 C  C   . ILE D 1 205 ? 6.55964   7.69306   -3.00035  1.000 38.19565 ? 203 ILE D C   1 
ATOM   7806 O  O   . ILE D 1 205 ? 6.48215   8.88783   -2.64366  1.000 35.63238 ? 203 ILE D O   1 
ATOM   7807 C  CB  . ILE D 1 205 ? 8.80606   6.56162   -3.37149  1.000 36.91568 ? 203 ILE D CB  1 
ATOM   7808 C  CG1 . ILE D 1 205 ? 9.99815   5.98876   -2.60648  1.000 36.30639 ? 203 ILE D CG1 1 
ATOM   7809 C  CG2 . ILE D 1 205 ? 9.22061   7.86936   -4.01139  1.000 33.15903 ? 203 ILE D CG2 1 
ATOM   7810 C  CD1 . ILE D 1 205 ? 11.09197  5.45571   -3.50484  1.000 34.44129 ? 203 ILE D CD1 1 
ATOM   7811 N  N   . MET D 1 206 ? 5.73016   7.15811   -3.89521  1.000 32.53547 ? 204 MET D N   1 
ATOM   7812 C  CA  . MET D 1 206 ? 4.63844   7.92646   -4.47197  1.000 34.17406 ? 204 MET D CA  1 
ATOM   7813 C  C   . MET D 1 206 ? 3.69961   8.44303   -3.38430  1.000 34.30369 ? 204 MET D C   1 
ATOM   7814 O  O   . MET D 1 206 ? 3.30175   9.61642   -3.39837  1.000 35.36802 ? 204 MET D O   1 
ATOM   7815 C  CB  . MET D 1 206 ? 3.89838   7.03653   -5.46685  1.000 34.54139 ? 204 MET D CB  1 
ATOM   7816 C  CG  . MET D 1 206 ? 2.73055   7.63666   -6.25063  1.000 36.36392 ? 204 MET D CG  1 
ATOM   7817 S  SD  . MET D 1 206 ? 1.25358   7.54549   -5.22423  1.000 37.46365 ? 204 MET D SD  1 
ATOM   7818 C  CE  . MET D 1 206 ? 0.85592   5.80804   -5.55357  1.000 34.64318 ? 204 MET D CE  1 
ATOM   7819 N  N   . VAL D 1 207 ? 3.33002   7.58082   -2.42916  1.000 34.72110 ? 205 VAL D N   1 
ATOM   7820 C  CA  . VAL D 1 207 ? 2.42254   8.00912   -1.36362  1.000 32.93214 ? 205 VAL D CA  1 
ATOM   7821 C  C   . VAL D 1 207 ? 3.04357   9.15949   -0.58141  1.000 29.65049 ? 205 VAL D C   1 
ATOM   7822 O  O   . VAL D 1 207 ? 2.36658   10.12769  -0.24243  1.000 35.14609 ? 205 VAL D O   1 
ATOM   7823 C  CB  . VAL D 1 207 ? 2.07171   6.82670   -0.43894  1.000 35.10927 ? 205 VAL D CB  1 
ATOM   7824 C  CG1 . VAL D 1 207 ? 1.44347   7.32582   0.87828   1.000 31.91618 ? 205 VAL D CG1 1 
ATOM   7825 C  CG2 . VAL D 1 207 ? 1.15659   5.79561   -1.13594  1.000 31.81660 ? 205 VAL D CG2 1 
ATOM   7826 N  N   . TRP D 1 208 ? 4.34378   9.06540   -0.28639  1.000 34.89597 ? 206 TRP D N   1 
ATOM   7827 C  CA  . TRP D 1 208 ? 5.05252   10.10859  0.45152   1.000 34.96208 ? 206 TRP D CA  1 
ATOM   7828 C  C   . TRP D 1 208 ? 4.93841   11.45840  -0.24642  1.000 37.44296 ? 206 TRP D C   1 
ATOM   7829 O  O   . TRP D 1 208 ? 4.82732   12.49974  0.41087   1.000 35.55399 ? 206 TRP D O   1 
ATOM   7830 C  CB  . TRP D 1 208 ? 6.52511   9.72985   0.58694   1.000 34.15134 ? 206 TRP D CB  1 
ATOM   7831 C  CG  . TRP D 1 208 ? 6.77244   8.60523   1.50906   1.000 38.97073 ? 206 TRP D CG  1 
ATOM   7832 C  CD1 . TRP D 1 208 ? 5.88763   8.06909   2.40649   1.000 42.33510 ? 206 TRP D CD1 1 
ATOM   7833 C  CD2 . TRP D 1 208 ? 7.95478   7.79696   1.57380   1.000 39.88627 ? 206 TRP D CD2 1 
ATOM   7834 N  NE1 . TRP D 1 208 ? 6.46217   6.99671   3.04968   1.000 48.13516 ? 206 TRP D NE1 1 
ATOM   7835 C  CE2 . TRP D 1 208 ? 7.72717   6.80152   2.55374   1.000 45.18201 ? 206 TRP D CE2 1 
ATOM   7836 C  CE3 . TRP D 1 208 ? 9.18747   7.82234   0.90542   1.000 42.48442 ? 206 TRP D CE3 1 
ATOM   7837 C  CZ2 . TRP D 1 208 ? 8.69158   5.83803   2.89118   1.000 45.92209 ? 206 TRP D CZ2 1 
ATOM   7838 C  CZ3 . TRP D 1 208 ? 10.14935  6.86343   1.23894   1.000 47.82747 ? 206 TRP D CZ3 1 
ATOM   7839 C  CH2 . TRP D 1 208 ? 9.89007   5.88004   2.22288   1.000 47.86747 ? 206 TRP D CH2 1 
ATOM   7840 N  N   . SER D 1 209 ? 5.00262   11.45785  -1.58101  1.000 31.31120 ? 207 SER D N   1 
ATOM   7841 C  CA  . SER D 1 209 ? 4.92728   12.68439  -2.36501  1.000 33.23427 ? 207 SER D CA  1 
ATOM   7842 C  C   . SER D 1 209 ? 3.50391   13.19236  -2.53937  1.000 34.73288 ? 207 SER D C   1 
ATOM   7843 O  O   . SER D 1 209 ? 3.31817   14.35687  -2.91809  1.000 39.16705 ? 207 SER D O   1 
ATOM   7844 C  CB  . SER D 1 209 ? 5.57729   12.44807  -3.74591  1.000 37.79761 ? 207 SER D CB  1 
ATOM   7845 O  OG  . SER D 1 209 ? 4.75553   11.62592  -4.59091  1.000 35.53537 ? 207 SER D OG  1 
ATOM   7846 N  N   . GLN D 1 210 ? 2.49843   12.35755  -2.27897  1.000 36.56067 ? 208 GLN D N   1 
ATOM   7847 C  CA  . GLN D 1 210 ? 1.09666   12.71005  -2.49166  1.000 35.28493 ? 208 GLN D CA  1 
ATOM   7848 C  C   . GLN D 1 210 ? 0.30800   12.90813  -1.20674  1.000 36.14547 ? 208 GLN D C   1 
ATOM   7849 O  O   . GLN D 1 210 ? -0.58279  13.76849  -1.14602  1.000 34.08428 ? 208 GLN D O   1 
ATOM   7850 C  CB  . GLN D 1 210 ? 0.42270   11.62250  -3.34113  1.000 31.49846 ? 208 GLN D CB  1 
ATOM   7851 C  CG  . GLN D 1 210 ? 1.11571   11.44759  -4.73688  1.000 33.94235 ? 208 GLN D CG  1 
ATOM   7852 C  CD  . GLN D 1 210 ? 0.63308   12.49145  -5.74077  1.000 33.92656 ? 208 GLN D CD  1 
ATOM   7853 O  OE1 . GLN D 1 210 ? -0.47598  13.00770  -5.61972  1.000 30.63908 ? 208 GLN D OE1 1 
ATOM   7854 N  NE2 . GLN D 1 210 ? 1.45680   12.79661  -6.73631  1.000 34.47697 ? 208 GLN D NE2 1 
ATOM   7855 N  N   . LEU D 1 211 ? 0.58123   12.09089  -0.19084  1.000 39.10903 ? 209 LEU D N   1 
ATOM   7856 C  CA  . LEU D 1 211 ? -0.05884  12.20689  1.10855   1.000 37.49468 ? 209 LEU D CA  1 
ATOM   7857 C  C   . LEU D 1 211 ? 0.89612   12.64386  2.20621   1.000 43.08745 ? 209 LEU D C   1 
ATOM   7858 O  O   . LEU D 1 211 ? 0.43337   13.03935  3.28382   1.000 40.31420 ? 209 LEU D O   1 
ATOM   7859 C  CB  . LEU D 1 211 ? -0.70503  10.87619  1.50552   1.000 33.85592 ? 209 LEU D CB  1 
ATOM   7860 C  CG  . LEU D 1 211 ? -1.82820  10.38518  0.59159   1.000 32.61757 ? 209 LEU D CG  1 
ATOM   7861 C  CD1 . LEU D 1 211 ? -2.42101  9.06303   1.09522   1.000 36.57843 ? 209 LEU D CD1 1 
ATOM   7862 C  CD2 . LEU D 1 211 ? -2.90664  11.45443  0.38513   1.000 36.05148 ? 209 LEU D CD2 1 
ATOM   7863 N  N   . GLY D 1 212 ? 2.20162   12.59437  1.96458   1.000 38.79608 ? 210 GLY D N   1 
ATOM   7864 C  CA  . GLY D 1 212 ? 3.15710   12.99000  2.98011   1.000 42.64676 ? 210 GLY D CA  1 
ATOM   7865 C  C   . GLY D 1 212 ? 3.67407   11.79125  3.74634   1.000 40.61557 ? 210 GLY D C   1 
ATOM   7866 O  O   . GLY D 1 212 ? 3.47062   10.63351  3.37203   1.000 39.72544 ? 210 GLY D O   1 
ATOM   7867 N  N   . GLY D 1 213 ? 4.39835   12.08675  4.81948   1.000 40.65112 ? 211 GLY D N   1 
ATOM   7868 C  CA  . GLY D 1 213 ? 4.85580   11.05144  5.72146   1.000 45.85819 ? 211 GLY D CA  1 
ATOM   7869 C  C   . GLY D 1 213 ? 6.21500   10.45434  5.43310   1.000 45.41191 ? 211 GLY D C   1 
ATOM   7870 O  O   . GLY D 1 213 ? 6.52759   9.39408   5.98928   1.000 42.26218 ? 211 GLY D O   1 
ATOM   7871 N  N   . GLN D 1 214 ? 7.03348   11.08969  4.58898   1.000 41.82519 ? 212 GLN D N   1 
ATOM   7872 C  CA  . GLN D 1 214 ? 8.38841   10.61399  4.33556   1.000 43.88625 ? 212 GLN D CA  1 
ATOM   7873 C  C   . GLN D 1 214 ? 9.12565   10.41836  5.65864   1.000 45.26588 ? 212 GLN D C   1 
ATOM   7874 O  O   . GLN D 1 214 ? 9.27917   11.38179  6.41766   1.000 46.80257 ? 212 GLN D O   1 
ATOM   7875 C  CB  . GLN D 1 214 ? 9.15177   11.59690  3.44673   1.000 43.15876 ? 212 GLN D CB  1 
ATOM   7876 C  CG  . GLN D 1 214 ? 10.17971  10.95048  2.53354   1.000 40.83987 ? 212 GLN D CG  1 
ATOM   7877 C  CD  . GLN D 1 214 ? 11.48703  10.62444  3.25215   1.000 45.89381 ? 212 GLN D CD  1 
ATOM   7878 O  OE1 . GLN D 1 214 ? 11.91180  11.35776  4.14730   1.000 44.21830 ? 212 GLN D OE1 1 
ATOM   7879 N  NE2 . GLN D 1 214 ? 12.11945  9.50517   2.87516   1.000 44.76553 ? 212 GLN D NE2 1 
ATOM   7880 N  N   . PRO D 1 215 ? 9.60522   9.20699   5.96138   1.000 51.39242 ? 213 PRO D N   1 
ATOM   7881 C  CA  . PRO D 1 215 ? 10.06976  8.92409   7.32916   1.000 51.98874 ? 213 PRO D CA  1 
ATOM   7882 C  C   . PRO D 1 215 ? 11.31362  9.69344   7.71893   1.000 55.03054 ? 213 PRO D C   1 
ATOM   7883 O  O   . PRO D 1 215 ? 11.58415  9.82164   8.91894   1.000 55.57046 ? 213 PRO D O   1 
ATOM   7884 C  CB  . PRO D 1 215 ? 10.33593  7.40564   7.31492   1.000 52.42822 ? 213 PRO D CB  1 
ATOM   7885 C  CG  . PRO D 1 215 ? 9.76083   6.89923   6.04319   1.000 51.97985 ? 213 PRO D CG  1 
ATOM   7886 C  CD  . PRO D 1 215 ? 9.78590   8.04965   5.07768   1.000 48.15080 ? 213 PRO D CD  1 
ATOM   7887 N  N   . GLY D 1 216 ? 12.06706  10.22563  6.75525   1.000 53.05055 ? 214 GLY D N   1 
ATOM   7888 C  CA  . GLY D 1 216 ? 13.28306  10.94878  7.08497   1.000 52.13549 ? 214 GLY D CA  1 
ATOM   7889 C  C   . GLY D 1 216 ? 13.04958  12.21505  7.87642   1.000 57.61765 ? 214 GLY D C   1 
ATOM   7890 O  O   . GLY D 1 216 ? 14.00436  12.75018  8.45376   1.000 60.50848 ? 214 GLY D O   1 
ATOM   7891 N  N   . LEU D 1 217 ? 11.80373  12.68230  7.94034   1.000 56.44532 ? 215 LEU D N   1 
ATOM   7892 C  CA  . LEU D 1 217 ? 11.44771  13.94571  8.56072   1.000 57.45090 ? 215 LEU D CA  1 
ATOM   7893 C  C   . LEU D 1 217 ? 11.25284  13.82428  10.07379  1.000 61.66274 ? 215 LEU D C   1 
ATOM   7894 O  O   . LEU D 1 217 ? 10.82132  12.78440  10.58623  1.000 68.36129 ? 215 LEU D O   1 
ATOM   7895 C  CB  . LEU D 1 217 ? 10.17416  14.48667  7.89863   1.000 58.50617 ? 215 LEU D CB  1 
ATOM   7896 C  CG  . LEU D 1 217 ? 10.26825  14.61399  6.36853   1.000 52.32269 ? 215 LEU D CG  1 
ATOM   7897 C  CD1 . LEU D 1 217 ? 8.90015   14.86048  5.73847   1.000 49.74405 ? 215 LEU D CD1 1 
ATOM   7898 C  CD2 . LEU D 1 217 ? 11.24916  15.71623  5.97555   1.000 49.19392 ? 215 LEU D CD2 1 
ATOM   7899 N  N   . GLU D 1 229 ? -1.37636  11.89694  14.03734  1.000 73.40088 ? 227 GLU D N   1 
ATOM   7900 C  CA  . GLU D 1 229 ? -0.11565  12.46150  13.56394  1.000 72.68909 ? 227 GLU D CA  1 
ATOM   7901 C  C   . GLU D 1 229 ? 0.13041   12.17143  12.08415  1.000 67.09197 ? 227 GLU D C   1 
ATOM   7902 O  O   . GLU D 1 229 ? 0.46753   13.07500  11.32266  1.000 65.88575 ? 227 GLU D O   1 
ATOM   7903 C  CB  . GLU D 1 229 ? 1.06500   11.93547  14.38594  1.000 73.70649 ? 227 GLU D CB  1 
ATOM   7904 C  CG  . GLU D 1 229 ? 2.33906   12.75496  14.18803  1.000 77.11256 ? 227 GLU D CG  1 
ATOM   7905 C  CD  . GLU D 1 229 ? 3.07140   13.04743  15.48667  1.000 80.87103 ? 227 GLU D CD  1 
ATOM   7906 O  OE1 . GLU D 1 229 ? 2.47894   13.68525  16.38432  1.000 80.65684 ? 227 GLU D OE1 1 
ATOM   7907 O  OE2 . GLU D 1 229 ? 4.25018   12.64570  15.60229  1.000 81.65180 ? 227 GLU D OE2 1 
ATOM   7908 N  N   . LEU D 1 230 ? -0.03513  10.90506  11.67674  1.000 65.99209 ? 228 LEU D N   1 
ATOM   7909 C  CA  . LEU D 1 230 ? 0.27582   10.62825  10.28294  1.000 61.03887 ? 228 LEU D CA  1 
ATOM   7910 C  C   . LEU D 1 230 ? -0.97556  10.75591  9.41677   1.000 58.52405 ? 228 LEU D C   1 
ATOM   7911 O  O   . LEU D 1 230 ? -2.09634  10.58751  9.90719   1.000 54.98145 ? 228 LEU D O   1 
ATOM   7912 C  CB  . LEU D 1 230 ? 0.86342   9.22362   10.13222  1.000 65.52013 ? 228 LEU D CB  1 
ATOM   7913 C  CG  . LEU D 1 230 ? 2.38558   9.03266   10.24144  1.000 68.66192 ? 228 LEU D CG  1 
ATOM   7914 C  CD1 . LEU D 1 230 ? 3.15122   10.00261  9.34603   1.000 61.87729 ? 228 LEU D CD1 1 
ATOM   7915 C  CD2 . LEU D 1 230 ? 2.85569   9.14529   11.69329  1.000 71.73982 ? 228 LEU D CD2 1 
ATOM   7916 N  N   . PRO D 1 231 ? -0.80963  11.09429  8.12008   1.000 59.31618 ? 229 PRO D N   1 
ATOM   7917 C  CA  . PRO D 1 231 ? -1.94472  11.04661  7.18414   1.000 54.44873 ? 229 PRO D CA  1 
ATOM   7918 C  C   . PRO D 1 231 ? -2.67915  9.71108   7.19575   1.000 56.93379 ? 229 PRO D C   1 
ATOM   7919 O  O   . PRO D 1 231 ? -2.17363  8.70313   7.70858   1.000 54.81984 ? 229 PRO D O   1 
ATOM   7920 C  CB  . PRO D 1 231 ? -1.29357  11.30086  5.81118   1.000 49.26037 ? 229 PRO D CB  1 
ATOM   7921 C  CG  . PRO D 1 231 ? 0.06907   11.84081  6.08182   1.000 49.65889 ? 229 PRO D CG  1 
ATOM   7922 C  CD  . PRO D 1 231 ? 0.34597   11.81915  7.56220   1.000 57.93183 ? 229 PRO D CD  1 
ATOM   7923 N  N   . GLN D 1 232 ? -3.87072  9.69279   6.60344   1.000 56.32028 ? 230 GLN D N   1 
ATOM   7924 C  CA  . GLN D 1 232 ? -4.73367  8.52439   6.62154   1.000 55.02737 ? 230 GLN D CA  1 
ATOM   7925 C  C   . GLN D 1 232 ? -5.23025  8.22554   5.21597   1.000 54.80807 ? 230 GLN D C   1 
ATOM   7926 O  O   . GLN D 1 232 ? -5.54824  9.14059   4.44420   1.000 51.20563 ? 230 GLN D O   1 
ATOM   7927 C  CB  . GLN D 1 232 ? -5.93440  8.74462   7.55280   1.000 57.93457 ? 230 GLN D CB  1 
ATOM   7928 C  CG  . GLN D 1 232 ? -5.55695  8.88294   9.02348   1.000 60.91246 ? 230 GLN D CG  1 
ATOM   7929 C  CD  . GLN D 1 232 ? -6.74210  9.25117   9.90189   1.000 65.31140 ? 230 GLN D CD  1 
ATOM   7930 O  OE1 . GLN D 1 232 ? -7.70417  9.87340   9.44368   1.000 64.95982 ? 230 GLN D OE1 1 
ATOM   7931 N  NE2 . GLN D 1 232 ? -6.65255  8.91604   11.18203  1.000 68.79458 ? 230 GLN D NE2 1 
ATOM   7932 N  N   . SER D 1 233 ? -5.30110  6.93756   4.89807   1.000 53.50454 ? 231 SER D N   1 
ATOM   7933 C  CA  . SER D 1 233 ? -5.96402  6.48546   3.69041   1.000 50.15166 ? 231 SER D CA  1 
ATOM   7934 C  C   . SER D 1 233 ? -7.45303  6.81886   3.73823   1.000 49.17728 ? 231 SER D C   1 
ATOM   7935 O  O   . SER D 1 233 ? -8.01255  7.16975   4.77488   1.000 52.77470 ? 231 SER D O   1 
ATOM   7936 C  CB  . SER D 1 233 ? -5.78154  4.97913   3.52437   1.000 50.78176 ? 231 SER D CB  1 
ATOM   7937 O  OG  . SER D 1 233 ? -6.64436  4.26528   4.39715   1.000 54.18176 ? 231 SER D OG  1 
ATOM   7938 N  N   . LEU D 1 234 ? -8.10036  6.68676   2.58285   1.000 48.21366 ? 232 LEU D N   1 
ATOM   7939 C  CA  . LEU D 1 234 ? -9.54552  6.84337   2.47326   1.000 47.71337 ? 232 LEU D CA  1 
ATOM   7940 C  C   . LEU D 1 234 ? -10.31164 5.86343   3.35610   1.000 50.91669 ? 232 LEU D C   1 
ATOM   7941 O  O   . LEU D 1 234 ? -11.54670 5.94132   3.42304   1.000 48.66586 ? 232 LEU D O   1 
ATOM   7942 C  CB  . LEU D 1 234 ? -9.94864  6.63224   1.02523   1.000 45.99391 ? 232 LEU D CB  1 
ATOM   7943 C  CG  . LEU D 1 234 ? -9.79402  7.75999   0.02116   1.000 46.64573 ? 232 LEU D CG  1 
ATOM   7944 C  CD1 . LEU D 1 234 ? -10.43109 7.23772   -1.25961  1.000 45.05677 ? 232 LEU D CD1 1 
ATOM   7945 C  CD2 . LEU D 1 234 ? -10.41438 9.12484   0.49907   1.000 39.25908 ? 232 LEU D CD2 1 
ATOM   7946 N  N   . GLY D 1 235 ? -9.61613  4.92078   3.98890   1.000 51.85445 ? 233 GLY D N   1 
ATOM   7947 C  CA  . GLY D 1 235 ? -10.22687 4.00880   4.93099   1.000 55.58065 ? 233 GLY D CA  1 
ATOM   7948 C  C   . GLY D 1 235 ? -9.93341  4.38174   6.37269   1.000 57.09428 ? 233 GLY D C   1 
ATOM   7949 O  O   . GLY D 1 235 ? -10.43156 3.73314   7.29628   1.000 60.80440 ? 233 GLY D O   1 
ATOM   7950 N  N   . GLY D 1 236 ? -9.10795  5.40792   6.58233   1.000 55.09695 ? 234 GLY D N   1 
ATOM   7951 C  CA  . GLY D 1 236 ? -8.81662  5.90281   7.91255   1.000 57.08854 ? 234 GLY D CA  1 
ATOM   7952 C  C   . GLY D 1 236 ? -7.53121  5.41378   8.55179   1.000 59.76439 ? 234 GLY D C   1 
ATOM   7953 O  O   . GLY D 1 236 ? -7.26443  5.77854   9.70370   1.000 58.68329 ? 234 GLY D O   1 
ATOM   7954 N  N   . ARG D 1 237 ? -6.71979  4.62013   7.84805   1.000 60.34077 ? 235 ARG D N   1 
ATOM   7955 C  CA  . ARG D 1 237 ? -5.53137  4.00561   8.43527   1.000 59.96048 ? 235 ARG D CA  1 
ATOM   7956 C  C   . ARG D 1 237 ? -4.30578  4.89208   8.23433   1.000 57.37493 ? 235 ARG D C   1 
ATOM   7957 O  O   . ARG D 1 237 ? -4.08338  5.41201   7.13441   1.000 58.88570 ? 235 ARG D O   1 
ATOM   7958 C  CB  . ARG D 1 237 ? -5.28552  2.62091   7.82598   1.000 56.93772 ? 235 ARG D CB  1 
ATOM   7959 N  N   . SER D 1 238 ? -3.50918  5.04919   9.29631   1.000 55.86229 ? 236 SER D N   1 
ATOM   7960 C  CA  . SER D 1 238 ? -2.23087  5.74586   9.19044   1.000 60.96440 ? 236 SER D CA  1 
ATOM   7961 C  C   . SER D 1 238 ? -1.35919  5.10662   8.11173   1.000 55.64080 ? 236 SER D C   1 
ATOM   7962 O  O   . SER D 1 238 ? -1.46444  3.91355   7.82378   1.000 57.04679 ? 236 SER D O   1 
ATOM   7963 C  CB  . SER D 1 238 ? -1.48819  5.72794   10.53561  1.000 58.98437 ? 236 SER D CB  1 
ATOM   7964 O  OG  . SER D 1 238 ? -0.13049  6.15733   10.40109  1.000 58.15727 ? 236 SER D OG  1 
ATOM   7965 N  N   . LEU D 1 239 ? -0.49182  5.91748   7.51075   1.000 55.57771 ? 237 LEU D N   1 
ATOM   7966 C  CA  . LEU D 1 239 ? 0.49163   5.40949   6.55954   1.000 53.26050 ? 237 LEU D CA  1 
ATOM   7967 C  C   . LEU D 1 239 ? 1.55614   4.52820   7.21034   1.000 54.06630 ? 237 LEU D C   1 
ATOM   7968 O  O   . LEU D 1 239 ? 2.37945   3.93530   6.49311   1.000 49.31796 ? 237 LEU D O   1 
ATOM   7969 C  CB  . LEU D 1 239 ? 1.12959   6.57883   5.80186   1.000 48.49574 ? 237 LEU D CB  1 
ATOM   7970 C  CG  . LEU D 1 239 ? 0.28436   7.16697   4.66591   1.000 46.77910 ? 237 LEU D CG  1 
ATOM   7971 C  CD1 . LEU D 1 239 ? -0.08261  6.03854   3.78318   1.000 50.78110 ? 237 LEU D CD1 1 
ATOM   7972 C  CD2 . LEU D 1 239 ? -0.98568  7.80889   5.09224   1.000 51.98782 ? 237 LEU D CD2 1 
ATOM   7973 N  N   . ALA D 1 240 ? 1.53563   4.39871   8.54009   1.000 52.49044 ? 238 ALA D N   1 
ATOM   7974 C  CA  . ALA D 1 240 ? 2.44112   3.47187   9.21369   1.000 52.75745 ? 238 ALA D CA  1 
ATOM   7975 C  C   . ALA D 1 240 ? 2.13782   2.01522   8.86528   1.000 49.35536 ? 238 ALA D C   1 
ATOM   7976 O  O   . ALA D 1 240 ? 3.05137   1.18077   8.83136   1.000 45.14370 ? 238 ALA D O   1 
ATOM   7977 C  CB  . ALA D 1 240 ? 2.36590   3.68221   10.72812  1.000 53.72673 ? 238 ALA D CB  1 
ATOM   7978 N  N   . THR D 1 241 ? 0.87347   1.67776   8.62268   1.000 45.95277 ? 239 THR D N   1 
ATOM   7979 C  CA  . THR D 1 241 ? 0.58133   0.29221   8.29374   1.000 49.64156 ? 239 THR D CA  1 
ATOM   7980 C  C   . THR D 1 241 ? 0.95542   -0.02263  6.85362   1.000 51.79927 ? 239 THR D C   1 
ATOM   7981 O  O   . THR D 1 241 ? 1.30635   -1.16966  6.54749   1.000 45.98366 ? 239 THR D O   1 
ATOM   7982 C  CB  . THR D 1 241 ? -0.89075  -0.03823  8.54594   1.000 50.10511 ? 239 THR D CB  1 
ATOM   7983 O  OG1 . THR D 1 241 ? -1.14412  -1.37789  8.12167   1.000 58.46688 ? 239 THR D OG1 1 
ATOM   7984 C  CG2 . THR D 1 241 ? -1.81567  0.90087   7.78934   1.000 53.16162 ? 239 THR D CG2 1 
ATOM   7985 N  N   . LEU D 1 242 ? 0.90837   0.97990   5.97006   1.000 47.60577 ? 240 LEU D N   1 
ATOM   7986 C  CA  . LEU D 1 242 ? 1.35812   0.76625   4.60219   1.000 43.87399 ? 240 LEU D CA  1 
ATOM   7987 C  C   . LEU D 1 242 ? 2.84985   0.46249   4.58159   1.000 44.94215 ? 240 LEU D C   1 
ATOM   7988 O  O   . LEU D 1 242 ? 3.29405   -0.49961  3.93885   1.000 41.99146 ? 240 LEU D O   1 
ATOM   7989 C  CB  . LEU D 1 242 ? 1.03358   1.99203   3.73720   1.000 42.84358 ? 240 LEU D CB  1 
ATOM   7990 C  CG  . LEU D 1 242 ? 1.54317   1.93438   2.27930   1.000 39.09357 ? 240 LEU D CG  1 
ATOM   7991 C  CD1 . LEU D 1 242 ? 0.84964   0.80364   1.50956   1.000 39.30107 ? 240 LEU D CD1 1 
ATOM   7992 C  CD2 . LEU D 1 242 ? 1.36775   3.25104   1.55086   1.000 40.39004 ? 240 LEU D CD2 1 
ATOM   7993 N  N   . GLU D 1 243 ? 3.63861   1.27114   5.29657   1.000 43.00411 ? 241 GLU D N   1 
ATOM   7994 C  CA  . GLU D 1 243 ? 5.08282   1.08487   5.29352   1.000 45.29894 ? 241 GLU D CA  1 
ATOM   7995 C  C   . GLU D 1 243 ? 5.45944   -0.30530  5.79116   1.000 47.09156 ? 241 GLU D C   1 
ATOM   7996 O  O   . GLU D 1 243 ? 6.38788   -0.93154  5.26804   1.000 45.70924 ? 241 GLU D O   1 
ATOM   7997 C  CB  . GLU D 1 243 ? 5.73741   2.16941   6.14257   1.000 44.42082 ? 241 GLU D CB  1 
ATOM   7998 C  CG  . GLU D 1 243 ? 7.24972   2.18589   6.12228   1.000 49.50943 ? 241 GLU D CG  1 
ATOM   7999 C  CD  . GLU D 1 243 ? 7.81326   3.51038   6.61425   1.000 52.05142 ? 241 GLU D CD  1 
ATOM   8000 O  OE1 . GLU D 1 243 ? 7.02969   4.47334   6.75864   1.000 53.90231 ? 241 GLU D OE1 1 
ATOM   8001 O  OE2 . GLU D 1 243 ? 9.04002   3.60333   6.84212   1.000 59.35475 ? 241 GLU D OE2 1 
ATOM   8002 N  N   . ALA D 1 244 ? 4.74177   -0.80885  6.79795   1.000 50.54901 ? 242 ALA D N   1 
ATOM   8003 C  CA  . ALA D 1 244 ? 5.08238   -2.11014  7.36180   1.000 46.93294 ? 242 ALA D CA  1 
ATOM   8004 C  C   . ALA D 1 244 ? 4.76751   -3.23120  6.38059   1.000 47.27250 ? 242 ALA D C   1 
ATOM   8005 O  O   . ALA D 1 244 ? 5.58413   -4.13497  6.17893   1.000 50.28939 ? 242 ALA D O   1 
ATOM   8006 C  CB  . ALA D 1 244 ? 4.34701   -2.31123  8.68377   1.000 45.10657 ? 242 ALA D CB  1 
ATOM   8007 N  N   . ARG D 1 245 ? 3.58607   -3.19411  5.75799   1.000 46.18708 ? 243 ARG D N   1 
ATOM   8008 C  CA  . ARG D 1 245 ? 3.23590   -4.21073  4.77037   1.000 45.03751 ? 243 ARG D CA  1 
ATOM   8009 C  C   . ARG D 1 245 ? 4.16994   -4.19045  3.56573   1.000 48.87334 ? 243 ARG D C   1 
ATOM   8010 O  O   . ARG D 1 245 ? 4.21578   -5.17251  2.80889   1.000 48.88316 ? 243 ARG D O   1 
ATOM   8011 C  CB  . ARG D 1 245 ? 1.79722   -4.00542  4.29352   1.000 47.77529 ? 243 ARG D CB  1 
ATOM   8012 C  CG  . ARG D 1 245 ? 0.73475   -4.06755  5.38690   1.000 51.31094 ? 243 ARG D CG  1 
ATOM   8013 C  CD  . ARG D 1 245 ? -0.62385  -4.45907  4.81051   1.000 51.34812 ? 243 ARG D CD  1 
ATOM   8014 N  NE  . ARG D 1 245 ? -1.05542  -3.56960  3.73167   1.000 52.34113 ? 243 ARG D NE  1 
ATOM   8015 C  CZ  . ARG D 1 245 ? -1.38252  -2.28655  3.86783   1.000 55.57674 ? 243 ARG D CZ  1 
ATOM   8016 N  NH1 . ARG D 1 245 ? -1.39747  -1.69211  5.05537   1.000 56.41159 ? 243 ARG D NH1 1 
ATOM   8017 N  NH2 . ARG D 1 245 ? -1.69937  -1.57533  2.77825   1.000 53.68305 ? 243 ARG D NH2 1 
ATOM   8018 N  N   . SER D 1 246 ? 4.92023   -3.09929  3.38169   1.000 44.13952 ? 244 SER D N   1 
ATOM   8019 C  CA  . SER D 1 246 ? 5.70907   -2.90051  2.17480   1.000 45.78974 ? 244 SER D CA  1 
ATOM   8020 C  C   . SER D 1 246 ? 6.95602   -3.77242  2.14258   1.000 46.12286 ? 244 SER D C   1 
ATOM   8021 O  O   . SER D 1 246 ? 7.50664   -4.00378  1.06199   1.000 48.60469 ? 244 SER D O   1 
ATOM   8022 C  CB  . SER D 1 246 ? 6.07524   -1.41463  2.02407   1.000 44.83550 ? 244 SER D CB  1 
ATOM   8023 O  OG  . SER D 1 246 ? 7.23924   -1.03784  2.75927   1.000 47.96548 ? 244 SER D OG  1 
ATOM   8024 N  N   . GLN D 1 247 ? 7.40333   -4.29402  3.27748   1.000 44.68486 ? 245 GLN D N   1 
ATOM   8025 C  CA  . GLN D 1 247 ? 8.57337   -5.15474  3.26499   1.000 46.83544 ? 245 GLN D CA  1 
ATOM   8026 C  C   . GLN D 1 247 ? 8.22132   -6.63954  3.23844   1.000 45.24654 ? 245 GLN D C   1 
ATOM   8027 O  O   . GLN D 1 247 ? 9.12814   -7.47322  3.32941   1.000 48.93176 ? 245 GLN D O   1 
ATOM   8028 C  CB  . GLN D 1 247 ? 9.47133   -4.83861  4.45912   1.000 49.88782 ? 245 GLN D CB  1 
ATOM   8029 C  CG  . GLN D 1 247 ? 10.53335  -3.81001  4.13496   1.000 54.98226 ? 245 GLN D CG  1 
ATOM   8030 C  CD  . GLN D 1 247 ? 11.01452  -3.06973  5.36232   1.000 54.62902 ? 245 GLN D CD  1 
ATOM   8031 O  OE1 . GLN D 1 247 ? 10.41623  -3.17262  6.43555   1.000 51.62813 ? 245 GLN D OE1 1 
ATOM   8032 N  NE2 . GLN D 1 247 ? 12.10228  -2.32447  5.21424   1.000 57.01362 ? 245 GLN D NE2 1 
ATOM   8033 N  N   . LEU D 1 248 ? 6.93513   -6.98453  3.10031   1.000 42.75379 ? 246 LEU D N   1 
ATOM   8034 C  CA  . LEU D 1 248 ? 6.49497   -8.37669  3.04561   1.000 45.06401 ? 246 LEU D CA  1 
ATOM   8035 C  C   . LEU D 1 248 ? 6.73840   -8.96126  1.65457   1.000 44.26515 ? 246 LEU D C   1 
ATOM   8036 O  O   . LEU D 1 248 ? 6.12338   -8.52665  0.67226   1.000 40.81210 ? 246 LEU D O   1 
ATOM   8037 C  CB  . LEU D 1 248 ? 5.01581   -8.48949  3.40661   1.000 44.69885 ? 246 LEU D CB  1 
ATOM   8038 C  CG  . LEU D 1 248 ? 4.61687   -8.05777  4.82465   1.000 53.52057 ? 246 LEU D CG  1 
ATOM   8039 C  CD1 . LEU D 1 248 ? 3.08971   -8.05908  5.00327   1.000 47.72414 ? 246 LEU D CD1 1 
ATOM   8040 C  CD2 . LEU D 1 248 ? 5.29700   -8.96900  5.85202   1.000 47.82795 ? 246 LEU D CD2 1 
ATOM   8041 N  N   . ALA D 1 249 ? 7.60472   -9.96550  1.57716   1.000 43.15047 ? 247 ALA D N   1 
ATOM   8042 C  CA  . ALA D 1 249 ? 7.88011   -10.63174 0.30815   1.000 44.53101 ? 247 ALA D CA  1 
ATOM   8043 C  C   . ALA D 1 249 ? 6.80377   -11.66079 -0.04648  1.000 39.39050 ? 247 ALA D C   1 
ATOM   8044 O  O   . ALA D 1 249 ? 5.97165   -12.06608 0.76887   1.000 40.18037 ? 247 ALA D O   1 
ATOM   8045 C  CB  . ALA D 1 249 ? 9.23761   -11.33137 0.33496   1.000 42.45517 ? 247 ALA D CB  1 
ATOM   8046 N  N   . LEU D 1 250 ? 6.85511   -12.09000 -1.30559  1.000 39.77553 ? 248 LEU D N   1 
ATOM   8047 C  CA  . LEU D 1 250 ? 6.00794   -13.17483 -1.78160  1.000 36.80803 ? 248 LEU D CA  1 
ATOM   8048 C  C   . LEU D 1 250 ? 6.48841   -14.52185 -1.25060  1.000 37.00808 ? 248 LEU D C   1 
ATOM   8049 O  O   . LEU D 1 250 ? 5.67634   -15.41413 -0.98369  1.000 39.45988 ? 248 LEU D O   1 
ATOM   8050 C  CB  . LEU D 1 250 ? 6.04007   -13.19066 -3.30761  1.000 36.96968 ? 248 LEU D CB  1 
ATOM   8051 C  CG  . LEU D 1 250 ? 5.25100   -12.12784 -4.05805  1.000 38.86675 ? 248 LEU D CG  1 
ATOM   8052 C  CD1 . LEU D 1 250 ? 5.27534   -12.47946 -5.56346  1.000 36.79464 ? 248 LEU D CD1 1 
ATOM   8053 C  CD2 . LEU D 1 250 ? 3.83978   -11.99156 -3.52739  1.000 39.82679 ? 248 LEU D CD2 1 
ATOM   8054 N  N   . PHE D 1 251 ? 7.81089   -14.69816 -1.14844  1.000 37.96187 ? 249 PHE D N   1 
ATOM   8055 C  CA  . PHE D 1 251 ? 8.45755   -15.98177 -0.84619  1.000 33.57504 ? 249 PHE D CA  1 
ATOM   8056 C  C   . PHE D 1 251 ? 9.46802   -15.78628 0.27433   1.000 35.79923 ? 249 PHE D C   1 
ATOM   8057 O  O   . PHE D 1 251 ? 10.68167  -15.84421 0.04637   1.000 34.27107 ? 249 PHE D O   1 
ATOM   8058 C  CB  . PHE D 1 251 ? 9.17209   -16.55852 -2.07416  1.000 37.90572 ? 249 PHE D CB  1 
ATOM   8059 C  CG  . PHE D 1 251 ? 8.35914   -16.54131 -3.33013  1.000 36.14827 ? 249 PHE D CG  1 
ATOM   8060 C  CD1 . PHE D 1 251 ? 7.08934   -17.10005 -3.34795  1.000 36.55118 ? 249 PHE D CD1 1 
ATOM   8061 C  CD2 . PHE D 1 251 ? 8.86901   -15.98228 -4.50125  1.000 34.82920 ? 249 PHE D CD2 1 
ATOM   8062 C  CE1 . PHE D 1 251 ? 6.32705   -17.08699 -4.48894  1.000 33.11984 ? 249 PHE D CE1 1 
ATOM   8063 C  CE2 . PHE D 1 251 ? 8.12086   -15.98010 -5.65282  1.000 32.64519 ? 249 PHE D CE2 1 
ATOM   8064 C  CZ  . PHE D 1 251 ? 6.84156   -16.53074 -5.64920  1.000 29.18920 ? 249 PHE D CZ  1 
ATOM   8065 N  N   . PRO D 1 252 ? 8.99897   -15.55082 1.50490   1.000 40.01422 ? 250 PRO D N   1 
ATOM   8066 C  CA  . PRO D 1 252 ? 9.93628   -15.27986 2.61537   1.000 39.61536 ? 250 PRO D CA  1 
ATOM   8067 C  C   . PRO D 1 252 ? 11.02027  -16.33723 2.77486   1.000 40.73538 ? 250 PRO D C   1 
ATOM   8068 O  O   . PRO D 1 252 ? 12.14847  -16.01533 3.18125   1.000 39.49763 ? 250 PRO D O   1 
ATOM   8069 C  CB  . PRO D 1 252 ? 9.02137   -15.24274 3.85174   1.000 40.85114 ? 250 PRO D CB  1 
ATOM   8070 C  CG  . PRO D 1 252 ? 7.64290   -15.05584 3.32895   1.000 40.78976 ? 250 PRO D CG  1 
ATOM   8071 C  CD  . PRO D 1 252 ? 7.59223   -15.61553 1.94163   1.000 36.70282 ? 250 PRO D CD  1 
ATOM   8072 N  N   . GLU D 1 253 ? 10.72042  -17.59085 2.42502   1.000 36.80599 ? 251 GLU D N   1 
ATOM   8073 C  CA  . GLU D 1 253 ? 11.69565  -18.66474 2.60339   1.000 42.59635 ? 251 GLU D CA  1 
ATOM   8074 C  C   . GLU D 1 253 ? 12.92964  -18.48411 1.71814   1.000 44.43227 ? 251 GLU D C   1 
ATOM   8075 O  O   . GLU D 1 253 ? 14.01403  -18.96266 2.07597   1.000 41.39727 ? 251 GLU D O   1 
ATOM   8076 C  CB  . GLU D 1 253 ? 11.02527  -20.01231 2.34297   1.000 44.32452 ? 251 GLU D CB  1 
ATOM   8077 C  CG  . GLU D 1 253 ? 9.95751   -20.34736 3.38264   1.000 47.31946 ? 251 GLU D CG  1 
ATOM   8078 C  CD  . GLU D 1 253 ? 10.51018  -20.30094 4.80638   1.000 49.93976 ? 251 GLU D CD  1 
ATOM   8079 O  OE1 . GLU D 1 253 ? 11.33938  -21.17326 5.15100   1.000 53.78673 ? 251 GLU D OE1 1 
ATOM   8080 O  OE2 . GLU D 1 253 ? 10.13670  -19.37635 5.56242   1.000 52.06807 ? 251 GLU D OE2 1 
ATOM   8081 N  N   . LEU D 1 254 ? 12.79970  -17.78737 0.57328   1.000 42.15546 ? 252 LEU D N   1 
ATOM   8082 C  CA  . LEU D 1 254 ? 13.97924  -17.43281 -0.21673  1.000 38.84431 ? 252 LEU D CA  1 
ATOM   8083 C  C   . LEU D 1 254 ? 14.88100  -16.46170 0.51937   1.000 41.79913 ? 252 LEU D C   1 
ATOM   8084 O  O   . LEU D 1 254 ? 16.11047  -16.61600 0.53157   1.000 40.43629 ? 252 LEU D O   1 
ATOM   8085 C  CB  . LEU D 1 254 ? 13.57690  -16.81789 -1.55713  1.000 43.58426 ? 252 LEU D CB  1 
ATOM   8086 C  CG  . LEU D 1 254 ? 12.68097  -17.58398 -2.48337  1.000 45.01035 ? 252 LEU D CG  1 
ATOM   8087 C  CD1 . LEU D 1 254 ? 12.73685  -16.90021 -3.81827  1.000 46.42231 ? 252 LEU D CD1 1 
ATOM   8088 C  CD2 . LEU D 1 254 ? 13.47284  -18.86674 -2.62258  1.000 50.41091 ? 252 LEU D CD2 1 
ATOM   8089 N  N   . TRP D 1 255 ? 14.29335  -15.41256 1.07254   1.000 38.31073 ? 253 TRP D N   1 
ATOM   8090 C  CA  . TRP D 1 255 ? 15.09218  -14.46080 1.82024   1.000 41.31381 ? 253 TRP D CA  1 
ATOM   8091 C  C   . TRP D 1 255 ? 15.65884  -15.10697 3.07360   1.000 42.79019 ? 253 TRP D C   1 
ATOM   8092 O  O   . TRP D 1 255 ? 16.78635  -14.78928 3.47277   1.000 43.33140 ? 253 TRP D O   1 
ATOM   8093 C  CB  . TRP D 1 255 ? 14.23114  -13.23977 2.13125   1.000 41.36785 ? 253 TRP D CB  1 
ATOM   8094 C  CG  . TRP D 1 255 ? 13.66302  -12.71195 0.85557   1.000 39.33668 ? 253 TRP D CG  1 
ATOM   8095 C  CD1 . TRP D 1 255 ? 12.46204  -13.03734 0.28799   1.000 40.13741 ? 253 TRP D CD1 1 
ATOM   8096 C  CD2 . TRP D 1 255 ? 14.29869  -11.80347 -0.04227  1.000 40.00061 ? 253 TRP D CD2 1 
ATOM   8097 N  NE1 . TRP D 1 255 ? 12.31099  -12.37492 -0.91364  1.000 39.56012 ? 253 TRP D NE1 1 
ATOM   8098 C  CE2 . TRP D 1 255 ? 13.42046  -11.60374 -1.12998  1.000 37.46160 ? 253 TRP D CE2 1 
ATOM   8099 C  CE3 . TRP D 1 255 ? 15.51750  -11.12159 -0.02244  1.000 39.57171 ? 253 TRP D CE3 1 
ATOM   8100 C  CZ2 . TRP D 1 255 ? 13.72826  -10.76267 -2.18873  1.000 39.11193 ? 253 TRP D CZ2 1 
ATOM   8101 C  CZ3 . TRP D 1 255 ? 15.82140  -10.26542 -1.07931  1.000 40.40659 ? 253 TRP D CZ3 1 
ATOM   8102 C  CH2 . TRP D 1 255 ? 14.92862  -10.09466 -2.14130  1.000 40.97046 ? 253 TRP D CH2 1 
ATOM   8103 N  N   . ARG D 1 256 ? 14.90480  -16.02667 3.68885   1.000 38.82575 ? 254 ARG D N   1 
ATOM   8104 C  CA  . ARG D 1 256 ? 15.45734  -16.77930 4.81112   1.000 44.70518 ? 254 ARG D CA  1 
ATOM   8105 C  C   . ARG D 1 256 ? 16.66313  -17.59615 4.37165   1.000 45.83508 ? 254 ARG D C   1 
ATOM   8106 O  O   . ARG D 1 256 ? 17.69816  -17.61734 5.05283   1.000 45.34637 ? 254 ARG D O   1 
ATOM   8107 C  CB  . ARG D 1 256 ? 14.39448  -17.68536 5.42481   1.000 46.97098 ? 254 ARG D CB  1 
ATOM   8108 C  CG  . ARG D 1 256 ? 14.98952  -18.73453 6.37487   1.000 51.12523 ? 254 ARG D CG  1 
ATOM   8109 C  CD  . ARG D 1 256 ? 14.22182  -18.81516 7.68796   1.000 50.41226 ? 254 ARG D CD  1 
ATOM   8110 N  NE  . ARG D 1 256 ? 12.80346  -18.53529 7.50132   1.000 53.92031 ? 254 ARG D NE  1 
ATOM   8111 C  CZ  . ARG D 1 256 ? 12.11695  -17.62752 8.18200   1.000 54.66357 ? 254 ARG D CZ  1 
ATOM   8112 N  NH1 . ARG D 1 256 ? 12.70290  -16.83582 9.07026   1.000 57.57928 ? 254 ARG D NH1 1 
ATOM   8113 N  NH2 . ARG D 1 256 ? 10.81127  -17.50241 7.95755   1.000 56.18169 ? 254 ARG D NH2 1 
ATOM   8114 N  N   . ALA D 1 257 ? 16.55255  -18.26565 3.21910   1.000 44.89639 ? 255 ALA D N   1 
ATOM   8115 C  CA  . ALA D 1 257 ? 17.67559  -19.04261 2.70793   1.000 44.11929 ? 255 ALA D CA  1 
ATOM   8116 C  C   . ALA D 1 257 ? 18.86385  -18.14935 2.39552   1.000 45.61996 ? 255 ALA D C   1 
ATOM   8117 O  O   . ALA D 1 257 ? 20.01750  -18.55117 2.59496   1.000 46.66921 ? 255 ALA D O   1 
ATOM   8118 C  CB  . ALA D 1 257 ? 17.25064  -19.83142 1.46935   1.000 45.32494 ? 255 ALA D CB  1 
ATOM   8119 N  N   . ALA D 1 258 ? 18.60543  -16.92405 1.92049   1.000 41.80811 ? 256 ALA D N   1 
ATOM   8120 C  CA  . ALA D 1 258 ? 19.69361  -15.98794 1.68513   1.000 43.19017 ? 256 ALA D CA  1 
ATOM   8121 C  C   . ALA D 1 258 ? 20.45592  -15.70051 2.97230   1.000 43.15236 ? 256 ALA D C   1 
ATOM   8122 O  O   . ALA D 1 258 ? 21.69335  -15.74276 2.99951   1.000 45.74651 ? 256 ALA D O   1 
ATOM   8123 C  CB  . ALA D 1 258 ? 19.15728  -14.68672 1.07303   1.000 41.40512 ? 256 ALA D CB  1 
ATOM   8124 N  N   . GLU D 1 259 ? 19.73803  -15.39665 4.05331   1.000 43.54038 ? 257 GLU D N   1 
ATOM   8125 C  CA  . GLU D 1 259 ? 20.43717  -15.12805 5.30145   1.000 44.80539 ? 257 GLU D CA  1 
ATOM   8126 C  C   . GLU D 1 259 ? 21.09559  -16.39205 5.84796   1.000 49.58990 ? 257 GLU D C   1 
ATOM   8127 O  O   . GLU D 1 259 ? 22.23645  -16.33569 6.32536   1.000 50.10516 ? 257 GLU D O   1 
ATOM   8128 C  CB  . GLU D 1 259 ? 19.49202  -14.50238 6.31991   1.000 49.34734 ? 257 GLU D CB  1 
ATOM   8129 C  CG  . GLU D 1 259 ? 20.28374  -13.71383 7.36908   1.000 52.57153 ? 257 GLU D CG  1 
ATOM   8130 C  CD  . GLU D 1 259 ? 19.44217  -13.10158 8.46493   1.000 56.28468 ? 257 GLU D CD  1 
ATOM   8131 O  OE1 . GLU D 1 259 ? 18.31647  -12.61784 8.16884   1.000 56.54790 ? 257 GLU D OE1 1 
ATOM   8132 O  OE2 . GLU D 1 259 ? 19.91781  -13.10017 9.62374   1.000 57.01921 ? 257 GLU D OE2 1 
ATOM   8133 N  N   . ASP D 1 260 ? 20.41775  -17.54551 5.74579   1.000 44.12720 ? 258 ASP D N   1 
ATOM   8134 C  CA  . ASP D 1 260 ? 21.05162  -18.81396 6.11618   1.000 48.29984 ? 258 ASP D CA  1 
ATOM   8135 C  C   . ASP D 1 260 ? 22.42267  -18.95057 5.45938   1.000 49.62926 ? 258 ASP D C   1 
ATOM   8136 O  O   . ASP D 1 260 ? 23.40538  -19.31438 6.11357   1.000 48.33667 ? 258 ASP D O   1 
ATOM   8137 C  CB  . ASP D 1 260 ? 20.15600  -20.00235 5.73470   1.000 45.46683 ? 258 ASP D CB  1 
ATOM   8138 C  CG  . ASP D 1 260 ? 18.91901  -20.11965 6.61550   1.000 51.45727 ? 258 ASP D CG  1 
ATOM   8139 O  OD1 . ASP D 1 260 ? 18.84445  -19.38909 7.62784   1.000 50.27198 ? 258 ASP D OD1 1 
ATOM   8140 O  OD2 . ASP D 1 260 ? 18.02481  -20.95218 6.30475   1.000 52.61637 ? 258 ASP D OD2 1 
ATOM   8141 N  N   . ALA D 1 261 ? 22.51604  -18.62365 4.16377   1.000 48.68767 ? 259 ALA D N   1 
ATOM   8142 C  CA  . ALA D 1 261 ? 23.79470  -18.75170 3.47097   1.000 47.63944 ? 259 ALA D CA  1 
ATOM   8143 C  C   . ALA D 1 261 ? 24.82180  -17.76157 3.99412   1.000 49.90916 ? 259 ALA D C   1 
ATOM   8144 O  O   . ALA D 1 261 ? 26.01695  -18.08029 4.04965   1.000 47.24370 ? 259 ALA D O   1 
ATOM   8145 C  CB  . ALA D 1 261 ? 23.60968  -18.55985 1.96668   1.000 47.97637 ? 259 ALA D CB  1 
ATOM   8146 N  N   . TYR D 1 262 ? 24.38735  -16.55446 4.36376   1.000 49.04643 ? 260 TYR D N   1 
ATOM   8147 C  CA  . TYR D 1 262 ? 25.32488  -15.58982 4.92719   1.000 50.75781 ? 260 TYR D CA  1 
ATOM   8148 C  C   . TYR D 1 262 ? 25.99896  -16.15496 6.17434   1.000 53.22961 ? 260 TYR D C   1 
ATOM   8149 O  O   . TYR D 1 262 ? 27.22048  -16.04520 6.33962   1.000 55.53559 ? 260 TYR D O   1 
ATOM   8150 C  CB  . TYR D 1 262 ? 24.61549  -14.27504 5.25085   1.000 48.25029 ? 260 TYR D CB  1 
ATOM   8151 C  CG  . TYR D 1 262 ? 25.42618  -13.40701 6.18668   1.000 53.00549 ? 260 TYR D CG  1 
ATOM   8152 C  CD1 . TYR D 1 262 ? 26.44534  -12.59130 5.70379   1.000 49.44724 ? 260 TYR D CD1 1 
ATOM   8153 C  CD2 . TYR D 1 262 ? 25.19365  -13.42609 7.55482   1.000 51.67350 ? 260 TYR D CD2 1 
ATOM   8154 C  CE1 . TYR D 1 262 ? 27.20332  -11.81707 6.55983   1.000 53.77838 ? 260 TYR D CE1 1 
ATOM   8155 C  CE2 . TYR D 1 262 ? 25.94580  -12.65748 8.41628   1.000 55.94327 ? 260 TYR D CE2 1 
ATOM   8156 C  CZ  . TYR D 1 262 ? 26.93923  -11.85280 7.92049   1.000 57.10153 ? 260 TYR D CZ  1 
ATOM   8157 O  OH  . TYR D 1 262 ? 27.66781  -11.09259 8.80040   1.000 60.22390 ? 260 TYR D OH  1 
ATOM   8158 N  N   . TRP D 1 263 ? 25.21628  -16.75159 7.07436   1.000 49.99088 ? 261 TRP D N   1 
ATOM   8159 C  CA  . TRP D 1 263 ? 25.82391  -17.33972 8.26502   1.000 55.54631 ? 261 TRP D CA  1 
ATOM   8160 C  C   . TRP D 1 263 ? 26.61876  -18.58962 7.90494   1.000 53.90965 ? 261 TRP D C   1 
ATOM   8161 O  O   . TRP D 1 263 ? 27.70230  -18.81997 8.45120   1.000 53.54233 ? 261 TRP D O   1 
ATOM   8162 C  CB  . TRP D 1 263 ? 24.76042  -17.67129 9.31450   1.000 54.05262 ? 261 TRP D CB  1 
ATOM   8163 C  CG  . TRP D 1 263 ? 23.94342  -16.50149 9.76059   1.000 54.68259 ? 261 TRP D CG  1 
ATOM   8164 C  CD1 . TRP D 1 263 ? 22.63227  -16.26560 9.46335   1.000 54.41722 ? 261 TRP D CD1 1 
ATOM   8165 C  CD2 . TRP D 1 263 ? 24.36553  -15.41304 10.59743  1.000 49.94620 ? 261 TRP D CD2 1 
ATOM   8166 N  NE1 . TRP D 1 263 ? 22.21581  -15.10312 10.05202  1.000 51.57636 ? 261 TRP D NE1 1 
ATOM   8167 C  CE2 . TRP D 1 263 ? 23.26245  -14.55392 10.74742  1.000 53.20127 ? 261 TRP D CE2 1 
ATOM   8168 C  CE3 . TRP D 1 263 ? 25.57165  -15.07666 11.22105  1.000 54.10239 ? 261 TRP D CE3 1 
ATOM   8169 C  CZ2 . TRP D 1 263 ? 23.32527  -13.37807 11.50331  1.000 54.99380 ? 261 TRP D CZ2 1 
ATOM   8170 C  CZ3 . TRP D 1 263 ? 25.63442  -13.91254 11.96900  1.000 57.67780 ? 261 TRP D CZ3 1 
ATOM   8171 C  CH2 . TRP D 1 263 ? 24.51669  -13.07769 12.10491  1.000 54.85672 ? 261 TRP D CH2 1 
ATOM   8172 N  N   . LEU D 1 264 ? 26.11287  -19.37860 6.95242   1.000 50.08053 ? 262 LEU D N   1 
ATOM   8173 C  CA  . LEU D 1 264 ? 26.75238  -20.64021 6.59519   1.000 52.88642 ? 262 LEU D CA  1 
ATOM   8174 C  C   . LEU D 1 264 ? 28.08453  -20.41529 5.88557   1.000 53.46846 ? 262 LEU D C   1 
ATOM   8175 O  O   . LEU D 1 264 ? 29.04941  -21.13656 6.14576   1.000 54.18304 ? 262 LEU D O   1 
ATOM   8176 C  CB  . LEU D 1 264 ? 25.79669  -21.46130 5.72405   1.000 51.58311 ? 262 LEU D CB  1 
ATOM   8177 C  CG  . LEU D 1 264 ? 24.68874  -22.21318 6.46628   1.000 52.31434 ? 262 LEU D CG  1 
ATOM   8178 C  CD1 . LEU D 1 264 ? 23.89146  -23.07105 5.52284   1.000 48.29183 ? 262 LEU D CD1 1 
ATOM   8179 C  CD2 . LEU D 1 264 ? 25.25766  -23.07585 7.59929   1.000 54.47718 ? 262 LEU D CD2 1 
ATOM   8180 N  N   . LEU D 1 265 ? 28.17330  -19.40857 5.00229   1.000 50.03638 ? 263 LEU D N   1 
ATOM   8181 C  CA  . LEU D 1 265 ? 29.35125  -19.24100 4.15860   1.000 50.68485 ? 263 LEU D CA  1 
ATOM   8182 C  C   . LEU D 1 265 ? 30.23460  -18.04400 4.50088   1.000 54.59670 ? 263 LEU D C   1 
ATOM   8183 O  O   . LEU D 1 265 ? 31.41250  -18.04678 4.11902   1.000 55.55309 ? 263 LEU D O   1 
ATOM   8184 C  CB  . LEU D 1 265 ? 28.94253  -19.12703 2.68103   1.000 48.14332 ? 263 LEU D CB  1 
ATOM   8185 C  CG  . LEU D 1 265 ? 28.14722  -20.29571 2.09038   1.000 53.38994 ? 263 LEU D CG  1 
ATOM   8186 C  CD1 . LEU D 1 265 ? 27.33526  -19.83883 0.89406   1.000 53.29029 ? 263 LEU D CD1 1 
ATOM   8187 C  CD2 . LEU D 1 265 ? 29.07684  -21.42437 1.69762   1.000 49.79300 ? 263 LEU D CD2 1 
ATOM   8188 N  N   . GLY D 1 266 ? 29.70627  -17.01558 5.16411   1.000 56.34563 ? 264 GLY D N   1 
ATOM   8189 C  CA  . GLY D 1 266 ? 30.51919  -15.84377 5.48480   1.000 55.57548 ? 264 GLY D CA  1 
ATOM   8190 C  C   . GLY D 1 266 ? 31.46382  -16.14309 6.63824   1.000 58.78748 ? 264 GLY D C   1 
ATOM   8191 O  O   . GLY D 1 266 ? 31.10800  -16.82803 7.59362   1.000 60.03258 ? 264 GLY D O   1 
ATOM   8192 N  N   . THR D 1 267 ? 32.68834  -15.61591 6.54614   1.000 62.76704 ? 265 THR D N   1 
ATOM   8193 C  CA  . THR D 1 267 ? 33.72940  -15.94835 7.51429   1.000 62.06872 ? 265 THR D CA  1 
ATOM   8194 C  C   . THR D 1 267 ? 34.28534  -14.72109 8.23182   1.000 66.15692 ? 265 THR D C   1 
ATOM   8195 O  O   . THR D 1 267 ? 35.46994  -14.69521 8.57169   1.000 69.26891 ? 265 THR D O   1 
ATOM   8196 C  CB  . THR D 1 267 ? 34.88488  -16.68123 6.84475   1.000 61.82231 ? 265 THR D CB  1 
ATOM   8197 O  OG1 . THR D 1 267 ? 35.29086  -15.95294 5.68078   1.000 58.17970 ? 265 THR D OG1 1 
ATOM   8198 C  CG2 . THR D 1 267 ? 34.46314  -18.08985 6.42856   1.000 60.98047 ? 265 THR D CG2 1 
ATOM   8199 N  N   . ARG D 1 268 ? 33.47540  -13.69258 8.46736   1.000 68.32651 ? 266 ARG D N   1 
ATOM   8200 C  CA  . ARG D 1 268 ? 33.98519  -12.50581 9.15775   1.000 69.46414 ? 266 ARG D CA  1 
ATOM   8201 C  C   . ARG D 1 268 ? 32.87328  -11.78655 9.91690   1.000 71.23819 ? 266 ARG D C   1 
ATOM   8202 O  O   . ARG D 1 268 ? 32.75051  -10.56199 9.86683   1.000 74.64725 ? 266 ARG D O   1 
ATOM   8203 C  CB  . ARG D 1 268 ? 34.66093  -11.54339 8.17946   1.000 72.06163 ? 266 ARG D CB  1 
ATOM   8204 C  CG  . ARG D 1 268 ? 33.83941  -11.17544 6.95133   1.000 66.33083 ? 266 ARG D CG  1 
ATOM   8205 C  CD  . ARG D 1 268 ? 34.75167  -10.72989 5.81601   1.000 62.66237 ? 266 ARG D CD  1 
ATOM   8206 N  NE  . ARG D 1 268 ? 35.48030  -9.51829  6.16990   1.000 64.95404 ? 266 ARG D NE  1 
ATOM   8207 C  CZ  . ARG D 1 268 ? 36.45637  -8.98544  5.44692   1.000 62.32317 ? 266 ARG D CZ  1 
ATOM   8208 N  NH1 . ARG D 1 268 ? 36.84755  -9.52699  4.30451   1.000 60.55966 ? 266 ARG D NH1 1 
ATOM   8209 N  NH2 . ARG D 1 268 ? 37.06160  -7.88515  5.88518   1.000 63.68421 ? 266 ARG D NH2 1 
ATOM   8210 N  N   . HIS D 1 269 ? 32.05496  -12.52268 10.66246  1.000 71.25322 ? 267 HIS D N   1 
ATOM   8211 C  CA  . HIS D 1 269 ? 30.90943  -11.84014 11.25022  1.000 71.94867 ? 267 HIS D CA  1 
ATOM   8212 C  C   . HIS D 1 269 ? 31.23209  -11.05471 12.52197  1.000 74.37738 ? 267 HIS D C   1 
ATOM   8213 O  O   . HIS D 1 269 ? 30.35666  -10.35493 13.03622  1.000 73.23943 ? 267 HIS D O   1 
ATOM   8214 C  CB  . HIS D 1 269 ? 29.76583  -12.81301 11.51822  1.000 65.00678 ? 267 HIS D CB  1 
ATOM   8215 C  CG  . HIS D 1 269 ? 28.57106  -12.14257 12.11318  1.000 66.75227 ? 267 HIS D CG  1 
ATOM   8216 N  ND1 . HIS D 1 269 ? 27.71852  -11.35517 11.37057  1.000 63.43567 ? 267 HIS D ND1 1 
ATOM   8217 C  CD2 . HIS D 1 269 ? 28.11391  -12.09856 13.38767  1.000 68.54187 ? 267 HIS D CD2 1 
ATOM   8218 C  CE1 . HIS D 1 269 ? 26.78411  -10.85824 12.16194  1.000 64.94550 ? 267 HIS D CE1 1 
ATOM   8219 N  NE2 . HIS D 1 269 ? 26.99746  -11.29900 13.38908  1.000 67.71814 ? 267 HIS D NE2 1 
ATOM   8220 N  N   . ASP D 1 270 ? 32.44998  -11.10577 13.03848  1.000 76.68609 ? 268 ASP D N   1 
ATOM   8221 C  CA  . ASP D 1 270 ? 32.81343  -10.19393 14.11925  1.000 73.36571 ? 268 ASP D CA  1 
ATOM   8222 C  C   . ASP D 1 270 ? 34.24648  -9.74290  13.93899  1.000 75.58146 ? 268 ASP D C   1 
ATOM   8223 O  O   . ASP D 1 270 ? 35.02189  -9.65484  14.89601  1.000 81.97478 ? 268 ASP D O   1 
ATOM   8224 C  CB  . ASP D 1 270 ? 32.57686  -10.83001 15.48944  1.000 73.67612 ? 268 ASP D CB  1 
ATOM   8225 C  CG  . ASP D 1 270 ? 31.12941  -10.67383 15.96163  1.000 75.78673 ? 268 ASP D CG  1 
ATOM   8226 O  OD1 . ASP D 1 270 ? 30.49107  -9.65403  15.61551  1.000 76.19653 ? 268 ASP D OD1 1 
ATOM   8227 O  OD2 . ASP D 1 270 ? 30.61600  -11.57784 16.65468  1.000 75.71907 ? 268 ASP D OD2 1 
ATOM   8228 N  N   . THR D 1 271 ? 34.59794  -9.43359  12.69559  1.000 78.27853 ? 269 THR D N   1 
ATOM   8229 C  CA  . THR D 1 271 ? 35.95127  -9.08482  12.29009  1.000 79.42139 ? 269 THR D CA  1 
ATOM   8230 C  C   . THR D 1 271 ? 36.13132  -7.56965  12.25416  1.000 76.93102 ? 269 THR D C   1 
ATOM   8231 O  O   . THR D 1 271 ? 35.18076  -6.82772  11.99408  1.000 80.17937 ? 269 THR D O   1 
ATOM   8232 C  CB  . THR D 1 271 ? 36.27026  -9.68995  10.89630  1.000 79.82281 ? 269 THR D CB  1 
ATOM   8233 O  OG1 . THR D 1 271 ? 36.58187  -11.07914 11.03989  1.000 75.52981 ? 269 THR D OG1 1 
ATOM   8234 C  CG2 . THR D 1 271 ? 37.43701  -8.96549  10.21087  1.000 76.86322 ? 269 THR D CG2 1 
HETATM 8235 C  CHA . HEM E 2 .   ? 26.53786  0.85777   1.70865   1.000 44.56477 ? 301 HEM A CHA 1 
HETATM 8236 C  CHB . HEM E 2 .   ? 27.01019  1.83888   -3.01981  1.000 40.71633 ? 301 HEM A CHB 1 
HETATM 8237 C  CHC . HEM E 2 .   ? 26.88091  -2.94306  -3.94961  1.000 40.42674 ? 301 HEM A CHC 1 
HETATM 8238 C  CHD . HEM E 2 .   ? 26.40026  -3.88580  0.74726   1.000 42.51112 ? 301 HEM A CHD 1 
HETATM 8239 C  C1A . HEM E 2 .   ? 26.60957  1.52639   0.50983   1.000 44.94194 ? 301 HEM A C1A 1 
HETATM 8240 C  C2A . HEM E 2 .   ? 26.47916  2.95764   0.35268   1.000 44.51589 ? 301 HEM A C2A 1 
HETATM 8241 C  C3A . HEM E 2 .   ? 26.61307  3.21785   -0.95103  1.000 45.26553 ? 301 HEM A C3A 1 
HETATM 8242 C  C4A . HEM E 2 .   ? 26.82761  1.97605   -1.65812  1.000 41.02158 ? 301 HEM A C4A 1 
HETATM 8243 C  CMA . HEM E 2 .   ? 26.53931  4.58821   -1.63816  1.000 38.05014 ? 301 HEM A CMA 1 
HETATM 8244 C  CAA . HEM E 2 .   ? 26.21237  3.96471   1.49767   1.000 44.80356 ? 301 HEM A CAA 1 
HETATM 8245 C  CBA . HEM E 2 .   ? 24.72622  4.32772   1.43473   1.000 47.96972 ? 301 HEM A CBA 1 
HETATM 8246 C  CGA . HEM E 2 .   ? 24.13793  4.76629   2.76048   1.000 55.27184 ? 301 HEM A CGA 1 
HETATM 8247 O  O1A . HEM E 2 .   ? 22.97644  5.26458   2.76403   1.000 54.29161 ? 301 HEM A O1A 1 
HETATM 8248 O  O2A . HEM E 2 .   ? 24.80850  4.61634   3.81820   1.000 58.26983 ? 301 HEM A O2A 1 
HETATM 8249 C  C1B . HEM E 2 .   ? 26.99747  0.61946   -3.67520  1.000 38.85609 ? 301 HEM A C1B 1 
HETATM 8250 C  C2B . HEM E 2 .   ? 27.05396  0.41735   -5.10813  1.000 40.74366 ? 301 HEM A C2B 1 
HETATM 8251 C  C3B . HEM E 2 .   ? 27.00864  -0.90716  -5.34355  1.000 39.49794 ? 301 HEM A C3B 1 
HETATM 8252 C  C4B . HEM E 2 .   ? 26.91967  -1.57404  -4.07198  1.000 39.66145 ? 301 HEM A C4B 1 
HETATM 8253 C  CMB . HEM E 2 .   ? 27.14847  1.58148   -6.11867  1.000 39.03243 ? 301 HEM A CMB 1 
HETATM 8254 C  CAB . HEM E 2 .   ? 27.03439  -1.71245  -6.67013  1.000 39.30500 ? 301 HEM A CAB 1 
HETATM 8255 C  CBB . HEM E 2 .   ? 26.83147  -1.15726  -7.87029  1.000 40.37659 ? 301 HEM A CBB 1 
HETATM 8256 C  C1C . HEM E 2 .   ? 26.78909  -3.64035  -2.77355  1.000 41.54315 ? 301 HEM A C1C 1 
HETATM 8257 C  C2C . HEM E 2 .   ? 26.82095  -5.07972  -2.60953  1.000 44.61506 ? 301 HEM A C2C 1 
HETATM 8258 C  C3C . HEM E 2 .   ? 26.68243  -5.31423  -1.29073  1.000 43.80968 ? 301 HEM A C3C 1 
HETATM 8259 C  C4C . HEM E 2 .   ? 26.55786  -4.04728  -0.60736  1.000 41.02744 ? 301 HEM A C4C 1 
HETATM 8260 C  CMC . HEM E 2 .   ? 26.99018  -6.09759  -3.77491  1.000 39.82303 ? 301 HEM A CMC 1 
HETATM 8261 C  CAC . HEM E 2 .   ? 26.63909  -6.62685  -0.49495  1.000 41.10954 ? 301 HEM A CAC 1 
HETATM 8262 C  CBC . HEM E 2 .   ? 26.50385  -7.81250  -1.07749  1.000 48.00227 ? 301 HEM A CBC 1 
HETATM 8263 C  C1D . HEM E 2 .   ? 26.42235  -2.67363  1.41852   1.000 42.68651 ? 301 HEM A C1D 1 
HETATM 8264 C  C2D . HEM E 2 .   ? 26.36073  -2.50266  2.85680   1.000 45.52465 ? 301 HEM A C2D 1 
HETATM 8265 C  C3D . HEM E 2 .   ? 26.40334  -1.19863  3.13533   1.000 45.51165 ? 301 HEM A C3D 1 
HETATM 8266 C  C4D . HEM E 2 .   ? 26.48447  -0.49657  1.86826   1.000 43.09856 ? 301 HEM A C4D 1 
HETATM 8267 C  CMD . HEM E 2 .   ? 26.28084  -3.67309  3.85681   1.000 48.97985 ? 301 HEM A CMD 1 
HETATM 8268 C  CAD . HEM E 2 .   ? 26.37287  -0.54465  4.53442   1.000 45.69597 ? 301 HEM A CAD 1 
HETATM 8269 C  CBD . HEM E 2 .   ? 27.79197  -0.10201  4.88338   1.000 50.50594 ? 301 HEM A CBD 1 
HETATM 8270 C  CGD . HEM E 2 .   ? 27.90990  0.14379   6.36788   1.000 57.91275 ? 301 HEM A CGD 1 
HETATM 8271 O  O1D . HEM E 2 .   ? 26.90767  0.59114   6.98866   1.000 59.04560 ? 301 HEM A O1D 1 
HETATM 8272 O  O2D . HEM E 2 .   ? 29.01356  -0.09742  6.93324   1.000 59.61734 ? 301 HEM A O2D 1 
HETATM 8273 N  NA  . HEM E 2 .   ? 26.82678  0.95545   -0.72978  1.000 40.88141 ? 301 HEM A NA  1 
HETATM 8274 N  NB  . HEM E 2 .   ? 26.91725  -0.61089  -3.07529  1.000 37.70149 ? 301 HEM A NB  1 
HETATM 8275 N  NC  . HEM E 2 .   ? 26.62622  -3.04226  -1.54094  1.000 41.71985 ? 301 HEM A NC  1 
HETATM 8276 N  ND  . HEM E 2 .   ? 26.48652  -1.42763  0.85021   1.000 40.39872 ? 301 HEM A ND  1 
HETATM 8277 FE FE  . HEM E 2 .   ? 26.78269  -1.04032  -1.06730  1.000 40.32414 ? 301 HEM A FE  1 
HETATM 8278 C  C   . CYN F 3 .   ? 28.89309  -0.89242  -1.14486  1.000 39.43506 ? 302 CYN A C   1 
HETATM 8279 N  N   . CYN F 3 .   ? 29.53625  -1.22144  -0.25998  1.000 40.39993 ? 302 CYN A N   1 
HETATM 8280 O  OXT . 78U G 4 .   ? 30.20905  -4.45361  3.58266   1.000 54.89342 ? 303 78U A OXT 1 
HETATM 8281 C  C   . 78U G 4 .   ? 29.89784  -5.07609  2.52692   1.000 52.27148 ? 303 78U A C   1 
HETATM 8282 O  O   . 78U G 4 .   ? 29.37956  -6.21132  2.59541   1.000 50.52324 ? 303 78U A O   1 
HETATM 8283 C  CA  . 78U G 4 .   ? 30.13368  -4.42013  1.16210   1.000 50.80636 ? 303 78U A CA  1 
HETATM 8284 N  N   . 78U G 4 .   ? 30.72424  -3.11622  1.40253   1.000 47.07710 ? 303 78U A N   1 
HETATM 8285 C  CB  . 78U G 4 .   ? 31.04241  -5.27121  0.27764   1.000 47.76155 ? 303 78U A CB  1 
HETATM 8286 C  CAG . 78U G 4 .   ? 30.29234  -6.46794  -0.31604  1.000 46.33623 ? 303 78U A CAG 1 
HETATM 8287 C  CG  . 78U G 4 .   ? 31.59664  -4.39007  -0.84722  1.000 48.69553 ? 303 78U A CG  1 
HETATM 8288 C  CD2 . 78U G 4 .   ? 32.62419  -3.74020  -1.46934  1.000 47.23802 ? 303 78U A CD2 1 
HETATM 8289 C  CE3 . 78U G 4 .   ? 33.98976  -3.64379  -1.15428  1.000 46.18167 ? 303 78U A CE3 1 
HETATM 8290 C  CZ3 . 78U G 4 .   ? 34.82270  -2.90919  -1.96898  1.000 47.32414 ? 303 78U A CZ3 1 
HETATM 8291 C  CH2 . 78U G 4 .   ? 34.30872  -2.28326  -3.09512  1.000 45.64247 ? 303 78U A CH2 1 
HETATM 8292 C  CZ2 . 78U G 4 .   ? 32.96211  -2.38597  -3.40950  1.000 40.35994 ? 303 78U A CZ2 1 
HETATM 8293 C  CE2 . 78U G 4 .   ? 32.11579  -3.10276  -2.57362  1.000 42.87323 ? 303 78U A CE2 1 
HETATM 8294 N  NE1 . 78U G 4 .   ? 30.77483  -3.38495  -2.64707  1.000 45.20391 ? 303 78U A NE1 1 
HETATM 8295 C  CD1 . 78U G 4 .   ? 30.44820  -4.17306  -1.58503  1.000 45.17997 ? 303 78U A CD1 1 
HETATM 8296 C  CHA . HEM H 2 .   ? 28.63401  5.27670   -35.51089 1.000 31.48468 ? 301 HEM B CHA 1 
HETATM 8297 C  CHB . HEM H 2 .   ? 28.71770  4.30772   -30.72506 1.000 26.49114 ? 301 HEM B CHB 1 
HETATM 8298 C  CHC . HEM H 2 .   ? 26.95041  8.79704   -30.04221 1.000 31.08382 ? 301 HEM B CHC 1 
HETATM 8299 C  CHD . HEM H 2 .   ? 26.89669  9.73786   -34.75955 1.000 31.26660 ? 301 HEM B CHD 1 
HETATM 8300 C  C1A . HEM H 2 .   ? 28.75379  4.63190   -34.29856 1.000 31.64932 ? 301 HEM B C1A 1 
HETATM 8301 C  C2A . HEM H 2 .   ? 29.11734  3.26583   -34.14874 1.000 31.30094 ? 301 HEM B C2A 1 
HETATM 8302 C  C3A . HEM H 2 .   ? 29.12904  2.99900   -32.84031 1.000 31.84869 ? 301 HEM B C3A 1 
HETATM 8303 C  C4A . HEM H 2 .   ? 28.78953  4.18138   -32.10464 1.000 29.32367 ? 301 HEM B C4A 1 
HETATM 8304 C  CMA . HEM H 2 .   ? 29.45930  1.65000   -32.19735 1.000 27.24722 ? 301 HEM B CMA 1 
HETATM 8305 C  CAA . HEM H 2 .   ? 29.36673  2.26337   -35.30231 1.000 32.73765 ? 301 HEM B CAA 1 
HETATM 8306 C  CBA . HEM H 2 .   ? 27.99797  1.59130   -35.47157 1.000 32.27881 ? 301 HEM B CBA 1 
HETATM 8307 C  CGA . HEM H 2 .   ? 27.73764  0.89826   -36.78654 1.000 43.97685 ? 301 HEM B CGA 1 
HETATM 8308 O  O1A . HEM H 2 .   ? 28.35418  1.26480   -37.80992 1.000 48.08742 ? 301 HEM B O1A 1 
HETATM 8309 O  O2A . HEM H 2 .   ? 26.87251  -0.01719  -36.82602 1.000 45.94752 ? 301 HEM B O2A 1 
HETATM 8310 C  C1B . HEM H 2 .   ? 28.23729  5.48729   -30.15306 1.000 30.26898 ? 301 HEM B C1B 1 
HETATM 8311 C  C2B . HEM H 2 .   ? 28.00215  5.69611   -28.72849 1.000 26.45372 ? 301 HEM B C2B 1 
HETATM 8312 C  C3B . HEM H 2 .   ? 27.53460  6.92225   -28.57291 1.000 30.78232 ? 301 HEM B C3B 1 
HETATM 8313 C  C4B . HEM H 2 .   ? 27.42343  7.52981   -29.87505 1.000 29.94544 ? 301 HEM B C4B 1 
HETATM 8314 C  CMB . HEM H 2 .   ? 28.35297  4.62019   -27.68180 1.000 28.45578 ? 301 HEM B CMB 1 
HETATM 8315 C  CAB . HEM H 2 .   ? 27.12179  7.67235   -27.28731 1.000 32.65681 ? 301 HEM B CAB 1 
HETATM 8316 C  CBB . HEM H 2 .   ? 26.77443  7.01803   -26.17808 1.000 29.88948 ? 301 HEM B CBB 1 
HETATM 8317 C  C1C . HEM H 2 .   ? 26.84283  9.47410   -31.21998 1.000 32.85450 ? 301 HEM B C1C 1 
HETATM 8318 C  C2C . HEM H 2 .   ? 26.48523  10.86427  -31.37401 1.000 34.81239 ? 301 HEM B C2C 1 
HETATM 8319 C  C3C . HEM H 2 .   ? 26.47375  11.08518  -32.69847 1.000 31.47240 ? 301 HEM B C3C 1 
HETATM 8320 C  C4C . HEM H 2 .   ? 26.80605  9.87934   -33.38871 1.000 29.62634 ? 301 HEM B C4C 1 
HETATM 8321 C  CMC . HEM H 2 .   ? 26.19980  11.88052  -30.20521 1.000 32.34868 ? 301 HEM B CMC 1 
HETATM 8322 C  CAC . HEM H 2 .   ? 26.15322  12.37670  -33.47276 1.000 29.56051 ? 301 HEM B CAC 1 
HETATM 8323 C  CBC . HEM H 2 .   ? 25.52629  13.35864  -32.85139 1.000 36.25606 ? 301 HEM B CBC 1 
HETATM 8324 C  C1D . HEM H 2 .   ? 27.37141  8.59161   -35.36685 1.000 30.16083 ? 301 HEM B C1D 1 
HETATM 8325 C  C2D . HEM H 2 .   ? 27.55924  8.42022   -36.78994 1.000 31.15446 ? 301 HEM B C2D 1 
HETATM 8326 C  C3D . HEM H 2 .   ? 28.03016  7.17977   -36.99886 1.000 29.92935 ? 301 HEM B C3D 1 
HETATM 8327 C  C4D . HEM H 2 .   ? 28.16143  6.54155   -35.70444 1.000 28.70996 ? 301 HEM B C4D 1 
HETATM 8328 C  CMD . HEM H 2 .   ? 27.22126  9.53520   -37.81333 1.000 30.10927 ? 301 HEM B CMD 1 
HETATM 8329 C  CAD . HEM H 2 .   ? 28.40289  6.48799   -38.33323 1.000 33.09400 ? 301 HEM B CAD 1 
HETATM 8330 C  CBD . HEM H 2 .   ? 29.91365  6.65752   -38.54685 1.000 39.20693 ? 301 HEM B CBD 1 
HETATM 8331 C  CGD . HEM H 2 .   ? 30.24783  6.52556   -40.01789 1.000 39.32779 ? 301 HEM B CGD 1 
HETATM 8332 O  O1D . HEM H 2 .   ? 29.49976  5.82302   -40.75634 1.000 43.60213 ? 301 HEM B O1D 1 
HETATM 8333 O  O2D . HEM H 2 .   ? 31.27657  7.09674   -40.44710 1.000 38.25513 ? 301 HEM B O2D 1 
HETATM 8334 N  NA  . HEM H 2 .   ? 28.57393  5.18660   -33.03250 1.000 30.40834 ? 301 HEM B NA  1 
HETATM 8335 N  NB  . HEM H 2 .   ? 27.83716  6.61096   -30.81887 1.000 29.05679 ? 301 HEM B NB  1 
HETATM 8336 N  NC  . HEM H 2 .   ? 27.01565  8.89034   -32.46296 1.000 32.77660 ? 301 HEM B NC  1 
HETATM 8337 N  ND  . HEM H 2 .   ? 27.77570  7.44307   -34.73148 1.000 28.50301 ? 301 HEM B ND  1 
HETATM 8338 FE FE  . HEM H 2 .   ? 27.75879  7.02608   -32.77286 1.000 31.02891 ? 301 HEM B FE  1 
HETATM 8339 C  C   . CYN I 3 .   ? 29.74902  7.52979   -32.23950 1.000 30.64625 ? 302 CYN B C   1 
HETATM 8340 N  N   . CYN I 3 .   ? 30.35384  8.19865   -32.92989 1.000 31.94392 ? 302 CYN B N   1 
HETATM 8341 O  OXT . 78U J 4 .   ? 29.23896  12.91592  -36.25093 1.000 32.52564 ? 303 78U B OXT 1 
HETATM 8342 C  C   . 78U J 4 .   ? 30.03095  11.95999  -36.01369 1.000 35.84609 ? 303 78U B C   1 
HETATM 8343 O  O   . 78U J 4 .   ? 30.67689  11.43886  -36.95860 1.000 37.86123 ? 303 78U B O   1 
HETATM 8344 C  CA  . 78U J 4 .   ? 30.19998  11.38303  -34.60249 1.000 35.50387 ? 303 78U B CA  1 
HETATM 8345 N  N   . 78U J 4 .   ? 31.07280  10.21799  -34.67892 1.000 34.25718 ? 303 78U B N   1 
HETATM 8346 C  CB  . 78U J 4 .   ? 30.78947  12.41578  -33.64335 1.000 35.29797 ? 303 78U B CB  1 
HETATM 8347 C  CAG . 78U J 4 .   ? 29.82114  13.55938  -33.30148 1.000 32.71338 ? 303 78U B CAG 1 
HETATM 8348 C  CG  . 78U J 4 .   ? 31.29470  11.70953  -32.37206 1.000 32.06419 ? 303 78U B CG  1 
HETATM 8349 C  CD2 . 78U J 4 .   ? 32.32923  11.38952  -31.54884 1.000 34.20737 ? 303 78U B CD2 1 
HETATM 8350 C  CE3 . 78U J 4 .   ? 33.70211  11.68826  -31.64493 1.000 35.77232 ? 303 78U B CE3 1 
HETATM 8351 C  CZ3 . 78U J 4 .   ? 34.55949  11.22903  -30.66286 1.000 36.72909 ? 303 78U B CZ3 1 
HETATM 8352 C  CH2 . 78U J 4 .   ? 34.08969  10.49012  -29.59084 1.000 32.12320 ? 303 78U B CH2 1 
HETATM 8353 C  CZ2 . 78U J 4 .   ? 32.74100  10.17934  -29.51746 1.000 31.84683 ? 303 78U B CZ2 1 
HETATM 8354 C  CE2 . 78U J 4 .   ? 31.85347  10.62626  -30.51439 1.000 37.01435 ? 303 78U B CE2 1 
HETATM 8355 N  NE1 . 78U J 4 .   ? 30.48298  10.47746  -30.68381 1.000 36.35384 ? 303 78U B NE1 1 
HETATM 8356 C  CD1 . 78U J 4 .   ? 30.14398  11.16529  -31.82928 1.000 36.65433 ? 303 78U B CD1 1 
HETATM 8357 C  CHA . HEM K 2 .   ? 1.11018   -3.89957  -37.67657 1.000 32.49530 ? 301 HEM C CHA 1 
HETATM 8358 C  CHB . HEM K 2 .   ? 0.36309   -2.97158  -32.95769 1.000 27.46490 ? 301 HEM C CHB 1 
HETATM 8359 C  CHC . HEM K 2 .   ? 1.97365   -7.44137  -31.97638 1.000 28.52347 ? 301 HEM C CHC 1 
HETATM 8360 C  CHD . HEM K 2 .   ? 2.68037   -8.36633  -36.65673 1.000 29.05367 ? 301 HEM C CHD 1 
HETATM 8361 C  C1A . HEM K 2 .   ? 0.81101   -3.27867  -36.48849 1.000 28.69982 ? 301 HEM C C1A 1 
HETATM 8362 C  C2A . HEM K 2 .   ? 0.38515   -1.91237  -36.35310 1.000 32.04215 ? 301 HEM C C2A 1 
HETATM 8363 C  C3A . HEM K 2 .   ? 0.19346   -1.65841  -35.06172 1.000 30.84952 ? 301 HEM C C3A 1 
HETATM 8364 C  C4A . HEM K 2 .   ? 0.47580   -2.85776  -34.32567 1.000 28.08822 ? 301 HEM C C4A 1 
HETATM 8365 C  CMA . HEM K 2 .   ? -0.24855  -0.34161  -34.39422 1.000 28.88201 ? 301 HEM C CMA 1 
HETATM 8366 C  CAA . HEM K 2 .   ? 0.25622   -0.92354  -37.52842 1.000 30.76984 ? 301 HEM C CAA 1 
HETATM 8367 C  CBA . HEM K 2 .   ? 1.56296   -0.12622  -37.46417 1.000 34.10229 ? 301 HEM C CBA 1 
HETATM 8368 C  CGA . HEM K 2 .   ? 2.13517   0.01223   -38.84774 1.000 42.46344 ? 301 HEM C CGA 1 
HETATM 8369 O  O1A . HEM K 2 .   ? 2.76349   1.06723   -39.12270 1.000 45.89355 ? 301 HEM C O1A 1 
HETATM 8370 O  O2A . HEM K 2 .   ? 1.95268   -0.94287  -39.66604 1.000 45.12658 ? 301 HEM C O2A 1 
HETATM 8371 C  C1B . HEM K 2 .   ? 0.74829   -4.11697  -32.27207 1.000 27.39611 ? 301 HEM C C1B 1 
HETATM 8372 C  C2B . HEM K 2 .   ? 0.75896   -4.29756  -30.83125 1.000 24.74306 ? 301 HEM C C2B 1 
HETATM 8373 C  C3B . HEM K 2 .   ? 1.20248   -5.54211  -30.58709 1.000 27.13826 ? 301 HEM C C3B 1 
HETATM 8374 C  C4B . HEM K 2 .   ? 1.49651   -6.16401  -31.85809 1.000 28.43107 ? 301 HEM C C4B 1 
HETATM 8375 C  CMB . HEM K 2 .   ? 0.28299   -3.20948  -29.83789 1.000 25.46447 ? 301 HEM C CMB 1 
HETATM 8376 C  CAB . HEM K 2 .   ? 1.43760   -6.31115  -29.27094 1.000 26.85279 ? 301 HEM C CAB 1 
HETATM 8377 C  CBB . HEM K 2 .   ? 1.60604   -5.69815  -28.09764 1.000 30.35293 ? 301 HEM C CBB 1 
HETATM 8378 C  C1C . HEM K 2 .   ? 2.22208   -8.11230  -33.14440 1.000 29.99532 ? 301 HEM C C1C 1 
HETATM 8379 C  C2C . HEM K 2 .   ? 2.57291   -9.50285  -33.27308 1.000 32.26585 ? 301 HEM C C2C 1 
HETATM 8380 C  C3C . HEM K 2 .   ? 2.75272   -9.73419  -34.59005 1.000 33.33180 ? 301 HEM C C3C 1 
HETATM 8381 C  C4C . HEM K 2 .   ? 2.54140   -8.51795  -35.30014 1.000 26.55941 ? 301 HEM C C4C 1 
HETATM 8382 C  CMC . HEM K 2 .   ? 2.66102   -10.52063 -32.08616 1.000 31.89385 ? 301 HEM C CMC 1 
HETATM 8383 C  CAC . HEM K 2 .   ? 3.14346   -11.02799 -35.34528 1.000 30.98107 ? 301 HEM C CAC 1 
HETATM 8384 C  CBC . HEM K 2 .   ? 3.88655   -11.95893 -34.76534 1.000 32.66525 ? 301 HEM C CBC 1 
HETATM 8385 C  C1D . HEM K 2 .   ? 2.31646   -7.23449  -37.33867 1.000 26.80724 ? 301 HEM C C1D 1 
HETATM 8386 C  C2D . HEM K 2 .   ? 2.34139   -7.07324  -38.77977 1.000 31.49247 ? 301 HEM C C2D 1 
HETATM 8387 C  C3D . HEM K 2 .   ? 1.90615   -5.84268  -39.06051 1.000 29.41074 ? 301 HEM C C3D 1 
HETATM 8388 C  C4D . HEM K 2 .   ? 1.59831   -5.18321  -37.80099 1.000 30.49187 ? 301 HEM C C4D 1 
HETATM 8389 C  CMD . HEM K 2 .   ? 2.79167   -8.18568  -39.76508 1.000 30.82384 ? 301 HEM C CMD 1 
HETATM 8390 C  CAD . HEM K 2 .   ? 1.71950   -5.19402  -40.44491 1.000 34.72569 ? 301 HEM C CAD 1 
HETATM 8391 C  CBD . HEM K 2 .   ? 0.23134   -5.33810  -40.78208 1.000 38.26439 ? 301 HEM C CBD 1 
HETATM 8392 C  CGD . HEM K 2 .   ? 0.00958   -5.22525  -42.27044 1.000 44.48630 ? 301 HEM C CGD 1 
HETATM 8393 O  O1D . HEM K 2 .   ? 0.78283   -4.48044  -42.92440 1.000 43.89483 ? 301 HEM C O1D 1 
HETATM 8394 O  O2D . HEM K 2 .   ? -0.94125  -5.87014  -42.80029 1.000 44.70775 ? 301 HEM C O2D 1 
HETATM 8395 N  NA  . HEM K 2 .   ? 0.83908   -3.86171  -35.23174 1.000 29.34899 ? 301 HEM C NA  1 
HETATM 8396 N  NB  . HEM K 2 .   ? 1.22307   -5.25565  -32.85035 1.000 25.23865 ? 301 HEM C NB  1 
HETATM 8397 N  NC  . HEM K 2 .   ? 2.25664   -7.51282  -34.38758 1.000 29.00239 ? 301 HEM C NC  1 
HETATM 8398 N  ND  . HEM K 2 .   ? 1.85947   -6.07362  -36.77597 1.000 27.15344 ? 301 HEM C ND  1 
HETATM 8399 FE FE  . HEM K 2 .   ? 1.56288   -5.65571  -34.77269 1.000 29.26296 ? 301 HEM C FE  1 
HETATM 8400 C  C   . CYN L 3 .   ? -0.41262  -6.34533  -35.06938 1.000 28.71085 ? 302 CYN C C   1 
HETATM 8401 N  N   . CYN L 3 .   ? -1.37769  -6.74861  -35.53862 1.000 33.79702 ? 302 CYN C N   1 
HETATM 8402 O  OXT . 78U M 4 .   ? -0.60291  -10.09623 -39.32978 1.000 35.13196 ? 303 78U C OXT 1 
HETATM 8403 C  C   . 78U M 4 .   ? -0.14978  -10.65196 -38.28703 1.000 34.81457 ? 303 78U C C   1 
HETATM 8404 O  O   . 78U M 4 .   ? 0.72644   -11.54474 -38.38238 1.000 33.83692 ? 303 78U C O   1 
HETATM 8405 C  CA  . 78U M 4 .   ? -0.61550  -10.10835 -36.93073 1.000 35.63946 ? 303 78U C CA  1 
HETATM 8406 N  N   . 78U M 4 .   ? -1.54371  -9.01021  -37.21859 1.000 32.68423 ? 303 78U C N   1 
HETATM 8407 C  CB  . 78U M 4 .   ? -1.30820  -11.13140 -36.03764 1.000 33.53785 ? 303 78U C CB  1 
HETATM 8408 C  CAG . 78U M 4 .   ? -0.37407  -12.21689 -35.47673 1.000 36.00303 ? 303 78U C CAG 1 
HETATM 8409 C  CG  . 78U M 4 .   ? -2.02019  -10.37345 -34.89564 1.000 32.75197 ? 303 78U C CG  1 
HETATM 8410 C  CD2 . 78U M 4 .   ? -3.18814  -10.04191 -34.28256 1.000 32.39059 ? 303 78U C CD2 1 
HETATM 8411 C  CE3 . 78U M 4 .   ? -4.50757  -10.37973 -34.61102 1.000 35.27881 ? 303 78U C CE3 1 
HETATM 8412 C  CZ3 . 78U M 4 .   ? -5.56412  -9.93542  -33.84424 1.000 33.08333 ? 303 78U C CZ3 1 
HETATM 8413 C  CH2 . 78U M 4 .   ? -5.31083  -9.13796  -32.75233 1.000 33.27263 ? 303 78U C CH2 1 
HETATM 8414 C  CZ2 . 78U M 4 .   ? -4.00425  -8.78468  -32.43068 1.000 35.66526 ? 303 78U C CZ2 1 
HETATM 8415 C  CE2 . 78U M 4 .   ? -2.92298  -9.23841  -33.20511 1.000 36.10803 ? 303 78U C CE2 1 
HETATM 8416 N  NE1 . 78U M 4 .   ? -1.54901  -9.04682  -33.13326 1.000 34.33148 ? 303 78U C NE1 1 
HETATM 8417 C  CD1 . 78U M 4 .   ? -0.99684  -9.77682  -34.17491 1.000 33.09168 ? 303 78U C CD1 1 
HETATM 8418 C  CHA . HEM N 2 .   ? -2.45621  0.68208   -0.61666  1.000 37.34071 ? 301 HEM D CHA 1 
HETATM 8419 C  CHB . HEM N 2 .   ? -2.26635  -0.32417  -5.40381  1.000 31.25465 ? 301 HEM D CHB 1 
HETATM 8420 C  CHC . HEM N 2 .   ? -2.10247  4.45993   -6.26161  1.000 32.61831 ? 301 HEM D CHC 1 
HETATM 8421 C  CHD . HEM N 2 .   ? -2.43064  5.44420   -1.53344  1.000 32.57149 ? 301 HEM D CHD 1 
HETATM 8422 C  C1A . HEM N 2 .   ? -2.41080  0.00653   -1.82727  1.000 36.83809 ? 301 HEM D C1A 1 
HETATM 8423 C  C2A . HEM N 2 .   ? -2.41892  -1.42148  -2.00672  1.000 37.96621 ? 301 HEM D C2A 1 
HETATM 8424 C  C3A . HEM N 2 .   ? -2.35481  -1.68865  -3.30887  1.000 35.70963 ? 301 HEM D C3A 1 
HETATM 8425 C  C4A . HEM N 2 .   ? -2.31345  -0.45037  -4.03183  1.000 31.77315 ? 301 HEM D C4A 1 
HETATM 8426 C  CMA . HEM N 2 .   ? -2.32709  -3.09205  -3.93828  1.000 32.08625 ? 301 HEM D CMA 1 
HETATM 8427 C  CAA . HEM N 2 .   ? -2.44635  -2.50734  -0.91929  1.000 36.11927 ? 301 HEM D CAA 1 
HETATM 8428 C  CBA . HEM N 2 .   ? -0.98244  -2.77912  -0.62732  1.000 40.30959 ? 301 HEM D CBA 1 
HETATM 8429 C  CGA . HEM N 2 .   ? -0.67778  -2.53786  0.82425   1.000 51.92835 ? 301 HEM D CGA 1 
HETATM 8430 O  O1A . HEM N 2 .   ? 0.34382   -3.11384  1.28204   1.000 56.29315 ? 301 HEM D O1A 1 
HETATM 8431 O  O2A . HEM N 2 .   ? -1.44346  -1.80071  1.52041   1.000 51.16479 ? 301 HEM D O2A 1 
HETATM 8432 C  C1B . HEM N 2 .   ? -2.20082  0.90895   -6.04865  1.000 29.59070 ? 301 HEM D C1B 1 
HETATM 8433 C  C2B . HEM N 2 .   ? -2.06134  1.11865   -7.48190  1.000 29.29979 ? 301 HEM D C2B 1 
HETATM 8434 C  C3B . HEM N 2 .   ? -2.00873  2.44268   -7.69880  1.000 30.97735 ? 301 HEM D C3B 1 
HETATM 8435 C  C4B . HEM N 2 .   ? -2.10599  3.09740   -6.41414  1.000 29.99224 ? 301 HEM D C4B 1 
HETATM 8436 C  CMB . HEM N 2 .   ? -2.01772  -0.05791  -8.48125  1.000 29.49076 ? 301 HEM D CMB 1 
HETATM 8437 C  CAB . HEM N 2 .   ? -1.87691  3.26327   -8.99529  1.000 30.03729 ? 301 HEM D CAB 1 
HETATM 8438 C  CBB . HEM N 2 .   ? -1.35341  2.77809   -10.12788 1.000 31.98340 ? 301 HEM D CBB 1 
HETATM 8439 C  C1C . HEM N 2 .   ? -2.23258  5.14342   -5.07756  1.000 32.83842 ? 301 HEM D C1C 1 
HETATM 8440 C  C2C . HEM N 2 .   ? -2.34938  6.58268   -4.93217  1.000 34.11900 ? 301 HEM D C2C 1 
HETATM 8441 C  C3C . HEM N 2 .   ? -2.45878  6.83083   -3.61480  1.000 33.80296 ? 301 HEM D C3C 1 
HETATM 8442 C  C4C . HEM N 2 .   ? -2.37870  5.58086   -2.90220  1.000 32.46459 ? 301 HEM D C4C 1 
HETATM 8443 C  CMC . HEM N 2 .   ? -2.37311  7.58697   -6.11669  1.000 28.66863 ? 301 HEM D CMC 1 
HETATM 8444 C  CAC . HEM N 2 .   ? -2.58042  8.17678   -2.88087  1.000 32.11932 ? 301 HEM D CAC 1 
HETATM 8445 C  CBC . HEM N 2 .   ? -1.94494  9.22815   -3.36874  1.000 36.65653 ? 301 HEM D CBC 1 
HETATM 8446 C  C1D . HEM N 2 .   ? -2.44330  4.23341   -0.84917  1.000 34.97024 ? 301 HEM D C1D 1 
HETATM 8447 C  C2D . HEM N 2 .   ? -2.50612  4.04569   0.59138   1.000 36.70097 ? 301 HEM D C2D 1 
HETATM 8448 C  C3D . HEM N 2 .   ? -2.52084  2.74032   0.85803   1.000 39.79474 ? 301 HEM D C3D 1 
HETATM 8449 C  C4D . HEM N 2 .   ? -2.45982  2.03840   -0.42110  1.000 34.96435 ? 301 HEM D C4D 1 
HETATM 8450 C  CMD . HEM N 2 .   ? -2.55869  5.17992   1.63609   1.000 35.89739 ? 301 HEM D CMD 1 
HETATM 8451 C  CAD . HEM N 2 .   ? -2.54824  2.13598   2.28904   1.000 37.86248 ? 301 HEM D CAD 1 
HETATM 8452 C  CBD . HEM N 2 .   ? -3.65917  1.12911   2.47319   1.000 45.65392 ? 301 HEM D CBD 1 
HETATM 8453 C  CGD . HEM N 2 .   ? -4.95348  1.79658   2.81278   1.000 52.11220 ? 301 HEM D CGD 1 
HETATM 8454 O  O1D . HEM N 2 .   ? -5.42603  1.63824   3.97815   1.000 51.44585 ? 301 HEM D O1D 1 
HETATM 8455 O  O2D . HEM N 2 .   ? -5.49363  2.47866   1.89282   1.000 52.01562 ? 301 HEM D O2D 1 
HETATM 8456 N  NA  . HEM N 2 .   ? -2.35779  0.58036   -3.09310  1.000 34.26777 ? 301 HEM D NA  1 
HETATM 8457 N  NB  . HEM N 2 .   ? -2.20052  2.12198   -5.43715  1.000 27.57306 ? 301 HEM D NB  1 
HETATM 8458 N  NC  . HEM N 2 .   ? -2.23161  4.56981   -3.83114  1.000 31.53513 ? 301 HEM D NC  1 
HETATM 8459 N  ND  . HEM N 2 .   ? -2.43520  2.99158   -1.42400  1.000 30.94078 ? 301 HEM D ND  1 
HETATM 8460 FE FE  . HEM N 2 .   ? -2.29159  2.53825   -3.39783  1.000 31.20763 ? 301 HEM D FE  1 
HETATM 8461 C  C   . CYN O 3 .   ? -4.32113  2.40998   -3.99433  1.000 29.97949 ? 302 CYN D C   1 
HETATM 8462 N  N   . CYN O 3 .   ? -5.16370  2.59711   -3.23454  1.000 32.14878 ? 302 CYN D N   1 
HETATM 8463 O  OXT . 78U P 4 .   ? -5.66320  7.71657   -0.21695  1.000 39.98800 ? 303 78U D OXT 1 
HETATM 8464 C  C   . 78U P 4 .   ? -6.17359  6.59269   -0.47926  1.000 42.69906 ? 303 78U D C   1 
HETATM 8465 O  O   . 78U P 4 .   ? -6.71010  5.90014   0.42282   1.000 47.92478 ? 303 78U D O   1 
HETATM 8466 C  CA  . 78U P 4 .   ? -6.14339  5.98918   -1.88083  1.000 39.69917 ? 303 78U D CA  1 
HETATM 8467 N  N   . 78U P 4 .   ? -6.64328  4.61057   -1.78900  1.000 40.43520 ? 303 78U D N   1 
HETATM 8468 C  CB  . 78U P 4 .   ? -7.00492  6.77872   -2.86392  1.000 38.56681 ? 303 78U D CB  1 
HETATM 8469 C  CAG . 78U P 4 .   ? -6.35668  8.10226   -3.30267  1.000 38.32448 ? 303 78U D CAG 1 
HETATM 8470 C  CG  . 78U P 4 .   ? -7.29814  5.85646   -4.07186  1.000 37.20797 ? 303 78U D CG  1 
HETATM 8471 C  CD2 . 78U P 4 .   ? -8.19398  5.20311   -4.86456  1.000 36.12690 ? 303 78U D CD2 1 
HETATM 8472 C  CE3 . 78U P 4 .   ? -9.59895  5.15230   -4.81457  1.000 35.32272 ? 303 78U D CE3 1 
HETATM 8473 C  CZ3 . 78U P 4 .   ? -10.29953 4.41347   -5.74679  1.000 38.47629 ? 303 78U D CZ3 1 
HETATM 8474 C  CH2 . 78U P 4 .   ? -9.59837  3.73667   -6.73788  1.000 36.94191 ? 303 78U D CH2 1 
HETATM 8475 C  CZ2 . 78U P 4 .   ? -8.21199  3.78936   -6.78792  1.000 35.27458 ? 303 78U D CZ2 1 
HETATM 8476 C  CE2 . 78U P 4 .   ? -7.50715  4.54176   -5.84169  1.000 34.57854 ? 303 78U D CE2 1 
HETATM 8477 N  NE1 . 78U P 4 .   ? -6.16365  4.78015   -5.64938  1.000 35.53452 ? 303 78U D NE1 1 
HETATM 8478 C  CD1 . 78U P 4 .   ? -6.03846  5.60592   -4.55898  1.000 34.38627 ? 303 78U D CD1 1 
HETATM 8479 O  O   . HOH Q 5 .   ? 34.60144  -1.10348  -24.68158 1.000 41.32295 ? 401 HOH A O   1 
HETATM 8480 O  O   . HOH Q 5 .   ? 25.99572  30.41089  -8.23657  1.000 41.46614 ? 402 HOH A O   1 
HETATM 8481 O  O   . HOH Q 5 .   ? 19.77243  30.90442  -5.75073  1.000 38.38610 ? 403 HOH A O   1 
HETATM 8482 O  O   . HOH Q 5 .   ? 14.32825  30.87269  -17.50480 1.000 41.18199 ? 404 HOH A O   1 
HETATM 8483 O  O   . HOH Q 5 .   ? 44.11877  7.20347   -27.15194 1.000 40.88639 ? 405 HOH A O   1 
HETATM 8484 O  O   . HOH Q 5 .   ? 45.59641  -15.38992 -12.26017 1.000 57.86941 ? 406 HOH A O   1 
HETATM 8485 O  O   . HOH Q 5 .   ? 4.66250   24.14911  2.38545   1.000 43.58197 ? 407 HOH A O   1 
HETATM 8486 O  O   . HOH Q 5 .   ? 9.76435   35.90453  -0.70971  1.000 38.54782 ? 408 HOH A O   1 
HETATM 8487 O  O   . HOH Q 5 .   ? 35.60072  1.56236   2.34767   1.000 52.80106 ? 409 HOH A O   1 
HETATM 8488 O  O   . HOH Q 5 .   ? 39.72052  0.94951   -31.38350 1.000 44.21406 ? 410 HOH A O   1 
HETATM 8489 O  O   . HOH Q 5 .   ? 14.86039  -9.21952  9.34203   1.000 52.32325 ? 411 HOH A O   1 
HETATM 8490 O  O   . HOH Q 5 .   ? 42.75696  -2.95689  -17.21317 1.000 46.47140 ? 412 HOH A O   1 
HETATM 8491 O  O   . HOH Q 5 .   ? 13.82775  15.26731  -13.01629 1.000 34.95400 ? 413 HOH A O   1 
HETATM 8492 O  O   . HOH Q 5 .   ? 24.20249  1.24293   -8.70475  1.000 39.47915 ? 414 HOH A O   1 
HETATM 8493 O  O   . HOH Q 5 .   ? 11.61832  -0.77053  -9.32330  1.000 42.35733 ? 415 HOH A O   1 
HETATM 8494 O  O   . HOH Q 5 .   ? 41.19578  8.19128   -35.69568 1.000 39.06622 ? 416 HOH A O   1 
HETATM 8495 O  O   . HOH Q 5 .   ? 43.68239  -7.74413  -18.40331 1.000 46.54305 ? 417 HOH A O   1 
HETATM 8496 O  O   . HOH Q 5 .   ? -0.85713  30.87738  -6.93016  1.000 41.14620 ? 418 HOH A O   1 
HETATM 8497 O  O   . HOH Q 5 .   ? 14.42653  18.63256  -19.39447 1.000 36.98259 ? 419 HOH A O   1 
HETATM 8498 O  O   . HOH Q 5 .   ? -0.64920  29.52346  -17.45525 1.000 40.82435 ? 420 HOH A O   1 
HETATM 8499 O  O   . HOH Q 5 .   ? 19.14044  -6.51403  -14.11371 1.000 38.41413 ? 421 HOH A O   1 
HETATM 8500 O  O   . HOH Q 5 .   ? -6.67073  33.64946  -10.49076 1.000 49.95468 ? 422 HOH A O   1 
HETATM 8501 O  O   . HOH Q 5 .   ? 18.92260  -8.11384  -16.57021 1.000 43.84538 ? 423 HOH A O   1 
HETATM 8502 O  O   . HOH Q 5 .   ? 17.36940  -11.90023 3.42361   1.000 42.90321 ? 424 HOH A O   1 
HETATM 8503 O  O   . HOH Q 5 .   ? 38.72498  15.08553  -25.32169 1.000 46.23300 ? 425 HOH A O   1 
HETATM 8504 O  O   . HOH Q 5 .   ? 36.92766  -10.43951 -29.62323 1.000 39.52224 ? 426 HOH A O   1 
HETATM 8505 O  O   . HOH Q 5 .   ? 3.14386   34.90275  -3.46031  1.000 43.47017 ? 427 HOH A O   1 
HETATM 8506 O  O   . HOH Q 5 .   ? 26.55605  20.05205  2.50474   1.000 50.37725 ? 428 HOH A O   1 
HETATM 8507 O  O   . HOH Q 5 .   ? 10.76361  18.85039  -17.02723 1.000 39.18831 ? 429 HOH A O   1 
HETATM 8508 O  O   . HOH Q 5 .   ? -0.08294  21.03822  -17.02351 1.000 31.00687 ? 430 HOH A O   1 
HETATM 8509 O  O   . HOH Q 5 .   ? 25.30843  29.01356  -4.77819  1.000 50.26635 ? 431 HOH A O   1 
HETATM 8510 O  O   . HOH Q 5 .   ? -0.99818  23.52129  -14.28003 1.000 34.12608 ? 432 HOH A O   1 
HETATM 8511 O  O   . HOH Q 5 .   ? 21.04351  7.55246   -7.80688  1.000 34.01699 ? 433 HOH A O   1 
HETATM 8512 O  O   . HOH Q 5 .   ? 32.37322  -11.16835 -14.46183 1.000 36.32466 ? 434 HOH A O   1 
HETATM 8513 O  O   . HOH Q 5 .   ? 43.13570  -14.54017 -12.92820 1.000 50.63469 ? 435 HOH A O   1 
HETATM 8514 O  O   . HOH Q 5 .   ? 2.02539   25.39910  -13.86791 1.000 35.74589 ? 436 HOH A O   1 
HETATM 8515 O  O   . HOH Q 5 .   ? 17.55209  -4.42166  -6.41610  1.000 36.93987 ? 437 HOH A O   1 
HETATM 8516 O  O   . HOH Q 5 .   ? -14.33386 15.33901  1.48352   1.000 48.37105 ? 438 HOH A O   1 
HETATM 8517 O  O   . HOH Q 5 .   ? 22.21361  29.83042  -3.57129  1.000 44.71204 ? 439 HOH A O   1 
HETATM 8518 O  O   . HOH Q 5 .   ? 27.88569  25.93991  -9.35834  1.000 44.40271 ? 440 HOH A O   1 
HETATM 8519 O  O   . HOH Q 5 .   ? 36.47743  -11.58796 -12.97352 1.000 37.15578 ? 441 HOH A O   1 
HETATM 8520 O  O   . HOH Q 5 .   ? 7.30411   18.63804  -14.66921 1.000 30.88029 ? 442 HOH A O   1 
HETATM 8521 O  O   . HOH Q 5 .   ? 9.78119   19.71039  -14.84184 1.000 30.36053 ? 443 HOH A O   1 
HETATM 8522 O  O   . HOH Q 5 .   ? 28.00697  12.81015  -6.75034  1.000 40.99856 ? 444 HOH A O   1 
HETATM 8523 O  O   . HOH Q 5 .   ? 31.31563  14.87305  -14.65723 1.000 42.92455 ? 445 HOH A O   1 
HETATM 8524 O  O   . HOH Q 5 .   ? 19.40223  -3.68520  -14.62870 1.000 33.76455 ? 446 HOH A O   1 
HETATM 8525 O  O   . HOH Q 5 .   ? 29.55095  -17.45595 -11.76057 1.000 38.97563 ? 447 HOH A O   1 
HETATM 8526 O  O   . HOH Q 5 .   ? 4.93366   22.17418  -8.79909  1.000 30.95185 ? 448 HOH A O   1 
HETATM 8527 O  O   . HOH Q 5 .   ? 43.17686  7.32303   -22.64243 1.000 43.54851 ? 449 HOH A O   1 
HETATM 8528 O  O   . HOH Q 5 .   ? -0.25885  23.20475  -2.30743  1.000 36.26192 ? 450 HOH A O   1 
HETATM 8529 O  O   . HOH Q 5 .   ? -8.21070  21.47309  -9.27096  1.000 39.40805 ? 451 HOH A O   1 
HETATM 8530 O  O   . HOH Q 5 .   ? 6.38202   13.47591  2.59648   1.000 37.59511 ? 452 HOH A O   1 
HETATM 8531 O  O   . HOH Q 5 .   ? 44.17078  4.37512   -28.03456 1.000 42.53586 ? 453 HOH A O   1 
HETATM 8532 O  O   . HOH Q 5 .   ? 40.92489  1.81562   -26.32202 1.000 36.95473 ? 454 HOH A O   1 
HETATM 8533 O  O   . HOH Q 5 .   ? -0.52912  19.11927  -15.03442 1.000 34.35410 ? 455 HOH A O   1 
HETATM 8534 O  O   . HOH Q 5 .   ? 31.31659  17.39180  -10.50182 1.000 46.55651 ? 456 HOH A O   1 
HETATM 8535 O  O   . HOH Q 5 .   ? 20.75532  -13.52513 -4.30647  1.000 45.21727 ? 457 HOH A O   1 
HETATM 8536 O  O   . HOH Q 5 .   ? 48.73912  2.66450   -23.65434 1.000 55.37949 ? 458 HOH A O   1 
HETATM 8537 O  O   . HOH Q 5 .   ? 0.47350   19.55717  -7.58250  1.000 29.99635 ? 459 HOH A O   1 
HETATM 8538 O  O   . HOH Q 5 .   ? 19.65176  18.22366  -19.85220 1.000 36.37216 ? 460 HOH A O   1 
HETATM 8539 O  O   . HOH Q 5 .   ? 25.06409  26.87508  -14.78631 1.000 37.81554 ? 461 HOH A O   1 
HETATM 8540 O  O   . HOH Q 5 .   ? 0.12384   29.78543  -0.05882  1.000 44.82087 ? 462 HOH A O   1 
HETATM 8541 O  O   . HOH Q 5 .   ? 3.18147   17.09218  -7.02542  1.000 35.20125 ? 463 HOH A O   1 
HETATM 8542 O  O   . HOH Q 5 .   ? 42.90846  10.72494  -18.79581 1.000 50.07892 ? 464 HOH A O   1 
HETATM 8543 O  O   . HOH Q 5 .   ? 20.31110  16.96016  2.19609   1.000 48.37845 ? 465 HOH A O   1 
HETATM 8544 O  O   . HOH Q 5 .   ? 11.90421  9.79447   -10.83019 1.000 37.58190 ? 466 HOH A O   1 
HETATM 8545 O  O   . HOH Q 5 .   ? 16.85635  -5.58402  8.41578   1.000 52.27459 ? 467 HOH A O   1 
HETATM 8546 O  O   . HOH Q 5 .   ? 6.59401   18.84636  -2.76911  1.000 35.38587 ? 468 HOH A O   1 
HETATM 8547 O  O   . HOH Q 5 .   ? 22.32565  34.83096  -16.47021 1.000 47.15204 ? 469 HOH A O   1 
HETATM 8548 O  O   . HOH Q 5 .   ? 7.50378   36.02780  -14.00276 1.000 42.01174 ? 470 HOH A O   1 
HETATM 8549 O  O   . HOH Q 5 .   ? 23.54296  27.53532  -2.75038  1.000 39.59093 ? 471 HOH A O   1 
HETATM 8550 O  O   . HOH Q 5 .   ? 21.65621  -14.60831 -14.64023 1.000 37.98671 ? 472 HOH A O   1 
HETATM 8551 O  O   . HOH Q 5 .   ? 42.43526  6.86308   -25.29661 1.000 40.03441 ? 473 HOH A O   1 
HETATM 8552 O  O   . HOH Q 5 .   ? 18.16159  6.63956   -17.81164 1.000 31.69523 ? 474 HOH A O   1 
HETATM 8553 O  O   . HOH Q 5 .   ? 45.69315  -8.18390  -30.18913 1.000 54.29614 ? 475 HOH A O   1 
HETATM 8554 O  O   . HOH Q 5 .   ? 29.69476  21.67480  -13.31142 1.000 40.35888 ? 476 HOH A O   1 
HETATM 8555 O  O   . HOH Q 5 .   ? 14.55426  4.92865   -8.86025  1.000 31.49885 ? 477 HOH A O   1 
HETATM 8556 O  O   . HOH Q 5 .   ? 46.83045  8.03642   -28.70664 1.000 54.11873 ? 478 HOH A O   1 
HETATM 8557 O  O   . HOH Q 5 .   ? -8.60003  26.44106  -7.61734  1.000 45.32518 ? 479 HOH A O   1 
HETATM 8558 O  O   . HOH Q 5 .   ? -9.321    21.767    -0.210    1.000 44.34372 ? 480 HOH A O   1 
HETATM 8559 O  O   . HOH Q 5 .   ? 39.24590  -2.37150  -31.43653 1.000 48.70742 ? 481 HOH A O   1 
HETATM 8560 O  O   . HOH Q 5 .   ? 4.36350   36.16698  -16.69872 1.000 45.19573 ? 482 HOH A O   1 
HETATM 8561 O  O   . HOH Q 5 .   ? 16.60392  29.74349  -17.99738 1.000 32.66236 ? 483 HOH A O   1 
HETATM 8562 O  O   . HOH Q 5 .   ? -2.56030  34.35914  -13.65944 1.000 50.36490 ? 484 HOH A O   1 
HETATM 8563 O  O   . HOH Q 5 .   ? 7.13229   28.50677  1.18077   1.000 42.46728 ? 485 HOH A O   1 
HETATM 8564 O  O   . HOH Q 5 .   ? 25.11896  -6.92708  13.62388  1.000 66.98428 ? 486 HOH A O   1 
HETATM 8565 O  O   . HOH Q 5 .   ? 25.69682  31.52711  -10.76062 1.000 42.07248 ? 487 HOH A O   1 
HETATM 8566 O  O   . HOH Q 5 .   ? 4.99814   15.98282  -9.40054  1.000 39.77896 ? 488 HOH A O   1 
HETATM 8567 O  O   . HOH Q 5 .   ? 48.87995  -6.90581  -26.34031 1.000 49.82157 ? 489 HOH A O   1 
HETATM 8568 O  O   . HOH Q 5 .   ? 4.42647   27.55211  1.48704   1.000 41.84589 ? 490 HOH A O   1 
HETATM 8569 O  O   . HOH Q 5 .   ? 35.13290  14.33816  -24.55680 1.000 44.55872 ? 491 HOH A O   1 
HETATM 8570 O  O   . HOH Q 5 .   ? 9.79604   32.72091  -16.81588 1.000 44.97741 ? 492 HOH A O   1 
HETATM 8571 O  O   . HOH Q 5 .   ? 43.36035  10.30836  -23.41963 1.000 48.47527 ? 493 HOH A O   1 
HETATM 8572 O  O   . HOH Q 5 .   ? -8.30185  23.63538  -7.50792  1.000 42.87424 ? 494 HOH A O   1 
HETATM 8573 O  O   . HOH Q 5 .   ? 37.31773  -21.01442 -28.03677 1.000 49.23731 ? 495 HOH A O   1 
HETATM 8574 O  O   . HOH Q 5 .   ? 38.41386  -16.57590 -13.82088 1.000 53.13406 ? 496 HOH A O   1 
HETATM 8575 O  O   . HOH Q 5 .   ? 10.84648  34.41270  -15.49063 1.000 50.48108 ? 497 HOH A O   1 
HETATM 8576 O  O   . HOH Q 5 .   ? 35.99517  -18.76314 -5.34977  1.000 54.58971 ? 498 HOH A O   1 
HETATM 8577 O  O   . HOH Q 5 .   ? -5.56908  35.14935  -12.03957 1.000 55.58934 ? 499 HOH A O   1 
HETATM 8578 O  O   . HOH Q 5 .   ? 27.96853  28.30210  -7.88259  1.000 48.88844 ? 500 HOH A O   1 
HETATM 8579 O  O   . HOH R 5 .   ? 19.80313  -3.01306  -43.45570 1.000 51.70035 ? 401 HOH B O   1 
HETATM 8580 O  O   . HOH R 5 .   ? 33.85718  23.42298  -14.92979 1.000 47.53163 ? 402 HOH B O   1 
HETATM 8581 O  O   . HOH R 5 .   ? 11.76804  -31.17931 -30.96673 1.000 39.08426 ? 403 HOH B O   1 
HETATM 8582 O  O   . HOH R 5 .   ? 41.42934  18.23040  -23.47588 1.000 52.13638 ? 404 HOH B O   1 
HETATM 8583 O  O   . HOH R 5 .   ? 3.66855   -33.72603 -33.24245 1.000 32.10424 ? 405 HOH B O   1 
HETATM 8584 O  O   . HOH R 5 .   ? 19.06742  -0.43942  -18.40800 1.000 41.99273 ? 406 HOH B O   1 
HETATM 8585 O  O   . HOH R 5 .   ? 37.67982  7.45619   -34.71527 1.000 37.29270 ? 407 HOH B O   1 
HETATM 8586 O  O   . HOH R 5 .   ? 21.84269  -9.46699  -39.40137 1.000 40.96637 ? 408 HOH B O   1 
HETATM 8587 O  O   . HOH R 5 .   ? 34.71023  19.45063  -29.59754 1.000 45.94531 ? 409 HOH B O   1 
HETATM 8588 O  O   . HOH R 5 .   ? 38.62785  18.51871  -13.61190 1.000 49.89397 ? 410 HOH B O   1 
HETATM 8589 O  O   . HOH R 5 .   ? 16.14449  -34.33682 -26.62873 1.000 38.58519 ? 411 HOH B O   1 
HETATM 8590 O  O   . HOH R 5 .   ? 25.37861  -30.52384 -26.62294 1.000 40.99175 ? 412 HOH B O   1 
HETATM 8591 O  O   . HOH R 5 .   ? 29.43652  -30.53822 -34.40153 1.000 50.99678 ? 413 HOH B O   1 
HETATM 8592 O  O   . HOH R 5 .   ? 26.53038  -2.60818  -37.56493 1.000 46.17520 ? 414 HOH B O   1 
HETATM 8593 O  O   . HOH R 5 .   ? 6.72656   -31.94073 -25.73098 1.000 37.73616 ? 415 HOH B O   1 
HETATM 8594 O  O   . HOH R 5 .   ? 15.67774  -23.79378 -38.95541 1.000 32.90854 ? 416 HOH B O   1 
HETATM 8595 O  O   . HOH R 5 .   ? 34.12329  21.63167  -16.99521 1.000 41.68922 ? 417 HOH B O   1 
HETATM 8596 O  O   . HOH R 5 .   ? 43.29367  7.26089   -15.29292 1.000 45.00827 ? 418 HOH B O   1 
HETATM 8597 O  O   . HOH R 5 .   ? 25.34117  -9.63647  -38.91865 1.000 42.18297 ? 419 HOH B O   1 
HETATM 8598 O  O   . HOH R 5 .   ? 32.16824  25.20126  -32.47521 1.000 39.86114 ? 420 HOH B O   1 
HETATM 8599 O  O   . HOH R 5 .   ? 22.91999  3.20552   -35.37020 1.000 31.33782 ? 421 HOH B O   1 
HETATM 8600 O  O   . HOH R 5 .   ? 14.19910  7.58426   -22.39812 1.000 42.34239 ? 422 HOH B O   1 
HETATM 8601 O  O   . HOH R 5 .   ? 19.89458  -16.10752 -15.94086 1.000 37.15562 ? 423 HOH B O   1 
HETATM 8602 O  O   . HOH R 5 .   ? 34.99056  -6.97695  -18.43529 1.000 40.36413 ? 424 HOH B O   1 
HETATM 8603 O  O   . HOH R 5 .   ? 38.35846  8.23162   -5.69257  1.000 47.67114 ? 425 HOH B O   1 
HETATM 8604 O  O   . HOH R 5 .   ? 33.47442  -20.96543 -30.87411 1.000 34.10802 ? 426 HOH B O   1 
HETATM 8605 O  O   . HOH R 5 .   ? 35.07621  26.62470  -26.01313 1.000 55.14108 ? 427 HOH B O   1 
HETATM 8606 O  O   . HOH R 5 .   ? 30.38094  18.36110  -3.31060  1.000 46.35582 ? 428 HOH B O   1 
HETATM 8607 O  O   . HOH R 5 .   ? -0.95801  -14.33033 -44.40612 1.000 40.48692 ? 429 HOH B O   1 
HETATM 8608 O  O   . HOH R 5 .   ? 26.48239  12.84296  -47.65605 1.000 51.03067 ? 430 HOH B O   1 
HETATM 8609 O  O   . HOH R 5 .   ? 1.33782   -15.81719 -43.56569 1.000 36.93077 ? 431 HOH B O   1 
HETATM 8610 O  O   . HOH R 5 .   ? 11.23283  -33.27363 -30.26602 1.000 42.63049 ? 432 HOH B O   1 
HETATM 8611 O  O   . HOH R 5 .   ? 41.99852  6.57829   -3.56396  1.000 52.13718 ? 433 HOH B O   1 
HETATM 8612 O  O   . HOH R 5 .   ? 27.53267  7.42721   -41.48189 1.000 45.36493 ? 434 HOH B O   1 
HETATM 8613 O  O   . HOH R 5 .   ? 25.02769  3.69369   -25.56858 1.000 29.54553 ? 435 HOH B O   1 
HETATM 8614 O  O   . HOH R 5 .   ? 9.26054   -35.62087 -23.97459 1.000 43.74950 ? 436 HOH B O   1 
HETATM 8615 O  O   . HOH R 5 .   ? 6.60437   -20.99800 -22.88544 1.000 27.53073 ? 437 HOH B O   1 
HETATM 8616 O  O   . HOH R 5 .   ? 36.33064  -23.24989 -25.20883 1.000 44.51402 ? 438 HOH B O   1 
HETATM 8617 O  O   . HOH R 5 .   ? 30.29415  25.13097  -9.50398  1.000 49.75128 ? 439 HOH B O   1 
HETATM 8618 O  O   . HOH R 5 .   ? 6.04379   -27.10151 -44.23591 1.000 31.18675 ? 440 HOH B O   1 
HETATM 8619 O  O   . HOH R 5 .   ? 33.83568  -0.89151  -37.10397 1.000 42.32646 ? 441 HOH B O   1 
HETATM 8620 O  O   . HOH R 5 .   ? 19.89882  -20.85556 -38.84438 1.000 43.02614 ? 442 HOH B O   1 
HETATM 8621 O  O   . HOH R 5 .   ? 27.89383  18.08269  -19.02825 1.000 33.62144 ? 443 HOH B O   1 
HETATM 8622 O  O   . HOH R 5 .   ? 9.03728   -20.79987 -29.89727 1.000 25.83443 ? 444 HOH B O   1 
HETATM 8623 O  O   . HOH R 5 .   ? 16.59018  -2.93858  -44.94833 1.000 50.62070 ? 445 HOH B O   1 
HETATM 8624 O  O   . HOH R 5 .   ? 46.24742  9.54737   -8.02421  1.000 62.38257 ? 446 HOH B O   1 
HETATM 8625 O  O   . HOH R 5 .   ? 7.27820   -22.69580 -20.62973 1.000 30.47755 ? 447 HOH B O   1 
HETATM 8626 O  O   . HOH R 5 .   ? 11.19257  -26.20669 -23.00093 1.000 30.72034 ? 448 HOH B O   1 
HETATM 8627 O  O   . HOH R 5 .   ? 1.93001   -26.04392 -38.99280 1.000 38.68480 ? 449 HOH B O   1 
HETATM 8628 O  O   . HOH R 5 .   ? 30.23318  -25.80244 -28.53986 1.000 36.21081 ? 450 HOH B O   1 
HETATM 8629 O  O   . HOH R 5 .   ? 39.59798  -12.61624 -15.62262 1.000 45.46090 ? 451 HOH B O   1 
HETATM 8630 O  O   . HOH R 5 .   ? 16.40184  -35.59280 -19.81793 1.000 38.64294 ? 452 HOH B O   1 
HETATM 8631 O  O   . HOH R 5 .   ? -0.14548  -34.49638 -28.80193 1.000 52.20756 ? 453 HOH B O   1 
HETATM 8632 O  O   . HOH R 5 .   ? 18.03635  6.82520   -20.45454 1.000 31.52129 ? 454 HOH B O   1 
HETATM 8633 O  O   . HOH R 5 .   ? 17.27620  0.81736   -39.58027 1.000 44.68297 ? 455 HOH B O   1 
HETATM 8634 O  O   . HOH R 5 .   ? 10.49556  -17.67434 -29.92892 1.000 34.25265 ? 456 HOH B O   1 
HETATM 8635 O  O   . HOH R 5 .   ? 42.69539  3.83422   -8.97816  1.000 49.52684 ? 457 HOH B O   1 
HETATM 8636 O  O   . HOH R 5 .   ? 13.70013  -21.89652 -27.74233 1.000 31.20012 ? 458 HOH B O   1 
HETATM 8637 O  O   . HOH R 5 .   ? 9.92634   -24.70494 -34.79348 1.000 30.96523 ? 459 HOH B O   1 
HETATM 8638 O  O   . HOH R 5 .   ? 32.89059  -23.87253 -30.43097 1.000 37.01364 ? 460 HOH B O   1 
HETATM 8639 O  O   . HOH R 5 .   ? 17.01634  17.89357  -20.46730 1.000 32.54729 ? 461 HOH B O   1 
HETATM 8640 O  O   . HOH R 5 .   ? 1.11768   -25.67369 -29.65813 1.000 33.27963 ? 462 HOH B O   1 
HETATM 8641 O  O   . HOH R 5 .   ? 13.97518  -33.19172 -28.39149 1.000 36.85367 ? 463 HOH B O   1 
HETATM 8642 O  O   . HOH R 5 .   ? 17.12324  7.19771   -28.94339 1.000 33.82779 ? 464 HOH B O   1 
HETATM 8643 O  O   . HOH R 5 .   ? 34.62151  -12.82799 -35.97906 1.000 44.29823 ? 465 HOH B O   1 
HETATM 8644 O  O   . HOH R 5 .   ? 7.38949   -25.48836 -23.36089 1.000 32.70180 ? 466 HOH B O   1 
HETATM 8645 O  O   . HOH R 5 .   ? 15.98777  10.75108  -18.85995 1.000 40.07426 ? 467 HOH B O   1 
HETATM 8646 O  O   . HOH R 5 .   ? 18.75583  8.77712   -43.84153 1.000 42.14033 ? 468 HOH B O   1 
HETATM 8647 O  O   . HOH R 5 .   ? 43.81723  0.58829   -12.73364 1.000 52.38388 ? 469 HOH B O   1 
HETATM 8648 O  O   . HOH R 5 .   ? 18.46501  15.59010  -28.17334 1.000 39.90844 ? 470 HOH B O   1 
HETATM 8649 O  O   . HOH R 5 .   ? 22.38971  -32.83792 -24.42836 1.000 45.80437 ? 471 HOH B O   1 
HETATM 8650 O  O   . HOH R 5 .   ? 17.02272  0.96126   -42.68526 1.000 46.83546 ? 472 HOH B O   1 
HETATM 8651 O  O   . HOH R 5 .   ? 1.41919   -18.76498 -42.87610 1.000 36.66889 ? 473 HOH B O   1 
HETATM 8652 O  O   . HOH R 5 .   ? 17.07572  9.47521   -21.00327 1.000 34.35184 ? 474 HOH B O   1 
HETATM 8653 O  O   . HOH R 5 .   ? 35.07098  -6.18667  -35.54902 1.000 43.69607 ? 475 HOH B O   1 
HETATM 8654 O  O   . HOH R 5 .   ? 19.41890  7.42351   -41.96262 1.000 45.88160 ? 476 HOH B O   1 
HETATM 8655 O  O   . HOH R 5 .   ? 31.98347  19.84801  -19.82578 1.000 37.58427 ? 477 HOH B O   1 
HETATM 8656 O  O   . HOH R 5 .   ? 16.39970  -18.34201 -21.21574 1.000 32.99361 ? 478 HOH B O   1 
HETATM 8657 O  O   . HOH R 5 .   ? 13.89584  -18.05704 -21.71461 1.000 30.84471 ? 479 HOH B O   1 
HETATM 8658 O  O   . HOH R 5 .   ? 2.89763   -30.25574 -31.08928 1.000 35.50350 ? 480 HOH B O   1 
HETATM 8659 O  O   . HOH R 5 .   ? 4.466     -21.326   -45.442   1.000 40.92965 ? 481 HOH B O   1 
HETATM 8660 O  O   . HOH R 5 .   ? 40.66516  21.19718  -13.96913 1.000 51.58992 ? 482 HOH B O   1 
HETATM 8661 O  O   . HOH R 5 .   ? 28.00564  -12.33278 -36.35627 1.000 45.51658 ? 483 HOH B O   1 
HETATM 8662 O  O   . HOH R 5 .   ? -2.48588  -13.62457 -50.50942 1.000 52.98179 ? 484 HOH B O   1 
HETATM 8663 O  O   . HOH R 5 .   ? 21.21578  14.96461  -50.45882 1.000 59.35747 ? 485 HOH B O   1 
HETATM 8664 O  O   . HOH R 5 .   ? 23.60287  23.20345  -22.17747 1.000 34.55802 ? 486 HOH B O   1 
HETATM 8665 O  O   . HOH R 5 .   ? 40.70058  22.68969  -24.27111 1.000 57.50482 ? 487 HOH B O   1 
HETATM 8666 O  O   . HOH R 5 .   ? 29.03313  19.76627  -37.99362 1.000 37.13753 ? 488 HOH B O   1 
HETATM 8667 O  O   . HOH R 5 .   ? 17.94039  16.80315  -30.59623 1.000 39.57180 ? 489 HOH B O   1 
HETATM 8668 O  O   . HOH R 5 .   ? 15.83229  -7.95527  -25.42302 1.000 36.01731 ? 490 HOH B O   1 
HETATM 8669 O  O   . HOH R 5 .   ? -3.15572  -24.67253 -39.51422 1.000 47.19383 ? 491 HOH B O   1 
HETATM 8670 O  O   . HOH R 5 .   ? 39.92914  13.48039  -14.55251 1.000 45.87916 ? 492 HOH B O   1 
HETATM 8671 O  O   . HOH R 5 .   ? 15.16162  -18.23341 -33.52808 1.000 30.32171 ? 493 HOH B O   1 
HETATM 8672 O  O   . HOH R 5 .   ? 17.24269  -2.75775  -26.88389 1.000 34.83290 ? 494 HOH B O   1 
HETATM 8673 O  O   . HOH R 5 .   ? 3.94417   -19.43985 -43.98746 1.000 36.32900 ? 495 HOH B O   1 
HETATM 8674 O  O   . HOH R 5 .   ? 34.99697  11.55102  -1.05860  1.000 51.16542 ? 496 HOH B O   1 
HETATM 8675 O  O   . HOH R 5 .   ? 23.54310  8.85097   -49.52504 1.000 49.81148 ? 497 HOH B O   1 
HETATM 8676 O  O   . HOH R 5 .   ? 11.06015  -15.96923 -27.31200 1.000 36.09939 ? 498 HOH B O   1 
HETATM 8677 O  O   . HOH R 5 .   ? 19.74848  -3.40162  -17.38191 1.000 33.23139 ? 499 HOH B O   1 
HETATM 8678 O  O   . HOH R 5 .   ? 33.11043  -20.35650 -18.68961 1.000 39.83857 ? 500 HOH B O   1 
HETATM 8679 O  O   . HOH R 5 .   ? 16.96237  18.88424  -32.87786 1.000 34.50815 ? 501 HOH B O   1 
HETATM 8680 O  O   . HOH R 5 .   ? 36.35670  8.76557   -1.09413  1.000 51.54812 ? 502 HOH B O   1 
HETATM 8681 O  O   . HOH R 5 .   ? 24.26867  -2.95542  -26.90450 1.000 29.44934 ? 503 HOH B O   1 
HETATM 8682 O  O   . HOH R 5 .   ? 41.38359  3.97753   -6.31764  1.000 48.60172 ? 504 HOH B O   1 
HETATM 8683 O  O   . HOH R 5 .   ? 35.94637  -14.00685 -19.80060 1.000 43.93298 ? 505 HOH B O   1 
HETATM 8684 O  O   . HOH R 5 .   ? 33.31686  -28.79289 -27.61159 1.000 49.87021 ? 506 HOH B O   1 
HETATM 8685 O  O   . HOH R 5 .   ? 19.69391  -34.50864 -21.51806 1.000 44.03375 ? 507 HOH B O   1 
HETATM 8686 O  O   . HOH R 5 .   ? 3.028     -27.109   -42.180   1.000 47.65934 ? 508 HOH B O   1 
HETATM 8687 O  O   . HOH R 5 .   ? 29.28319  -10.38895 -36.07055 1.000 43.30919 ? 509 HOH B O   1 
HETATM 8688 O  O   . HOH R 5 .   ? 38.10565  -16.67378 -23.34560 1.000 48.32747 ? 510 HOH B O   1 
HETATM 8689 O  O   . HOH R 5 .   ? 28.38875  -4.23355  -37.85366 1.000 52.56369 ? 511 HOH B O   1 
HETATM 8690 O  O   . HOH R 5 .   ? 20.37335  2.96194   -45.78892 1.000 45.47564 ? 512 HOH B O   1 
HETATM 8691 O  O   . HOH R 5 .   ? 24.01985  1.12734   -37.28115 1.000 36.65591 ? 513 HOH B O   1 
HETATM 8692 O  O   . HOH R 5 .   ? 33.31838  24.04265  -20.49526 1.000 46.37785 ? 514 HOH B O   1 
HETATM 8693 O  O   . HOH R 5 .   ? 31.22425  26.11508  -34.67140 1.000 39.01257 ? 515 HOH B O   1 
HETATM 8694 O  O   . HOH R 5 .   ? 1.75702   -21.52553 -45.82045 1.000 45.55982 ? 516 HOH B O   1 
HETATM 8695 O  O   . HOH R 5 .   ? 19.37655  -26.65442 -37.20255 1.000 37.44393 ? 517 HOH B O   1 
HETATM 8696 O  O   . HOH R 5 .   ? -1.30914  -14.29224 -46.94444 1.000 46.64694 ? 518 HOH B O   1 
HETATM 8697 O  O   . HOH R 5 .   ? 24.39682  -14.18703 -14.42191 1.000 40.87235 ? 519 HOH B O   1 
HETATM 8698 O  O   . HOH R 5 .   ? 16.46827  -26.28423 -37.89301 1.000 32.17913 ? 520 HOH B O   1 
HETATM 8699 O  O   . HOH R 5 .   ? 35.64061  -24.61491 -22.79601 1.000 49.14827 ? 521 HOH B O   1 
HETATM 8700 O  O   . HOH R 5 .   ? 27.66521  28.59604  -4.94378  1.000 50.54567 ? 522 HOH B O   1 
HETATM 8701 O  O   . HOH R 5 .   ? 33.53854  17.11810  -11.41156 1.000 46.93872 ? 523 HOH B O   1 
HETATM 8702 O  O   . HOH R 5 .   ? -5.04419  -13.89226 -51.75955 1.000 61.11415 ? 524 HOH B O   1 
HETATM 8703 O  O   . HOH R 5 .   ? 21.31684  -20.41672 -40.51826 1.000 49.33785 ? 525 HOH B O   1 
HETATM 8704 O  O   . HOH R 5 .   ? 23.25421  16.23188  -50.38208 1.000 55.53966 ? 526 HOH B O   1 
HETATM 8705 O  O   . HOH R 5 .   ? 32.24147  25.10593  -28.20673 1.000 51.54942 ? 527 HOH B O   1 
HETATM 8706 O  O   . HOH R 5 .   ? 34.47908  15.81511  -26.37605 1.000 46.07174 ? 528 HOH B O   1 
HETATM 8707 O  O   . HOH R 5 .   ? 37.38030  16.67777  -27.16365 1.000 50.63362 ? 529 HOH B O   1 
HETATM 8708 O  O   . HOH R 5 .   ? 6.79957   11.61022  -42.45620 1.000 44.13365 ? 530 HOH B O   1 
HETATM 8709 O  O   . HOH R 5 .   ? 27.66940  -11.75417 -38.50278 1.000 47.06985 ? 531 HOH B O   1 
HETATM 8710 O  O   . HOH R 5 .   ? 1.90758   -27.50518 -31.60557 1.000 35.97775 ? 532 HOH B O   1 
HETATM 8711 O  O   . HOH R 5 .   ? -10.71355 -3.17560  -43.54866 1.000 56.55078 ? 533 HOH B O   1 
HETATM 8712 O  O   . HOH R 5 .   ? 36.60485  -16.64362 -20.00314 1.000 49.48608 ? 534 HOH B O   1 
HETATM 8713 O  O   . HOH R 5 .   ? -1.66393  -26.38867 -28.49490 1.000 50.57335 ? 535 HOH B O   1 
HETATM 8714 O  O   . HOH R 5 .   ? 30.49471  27.27698  -25.86058 1.000 52.02322 ? 536 HOH B O   1 
HETATM 8715 O  O   . HOH R 5 .   ? 34.42125  18.02494  -27.68429 1.000 52.31323 ? 537 HOH B O   1 
HETATM 8716 O  O   . HOH R 5 .   ? 32.13868  24.94147  -18.56167 1.000 54.42008 ? 538 HOH B O   1 
HETATM 8717 O  O   . HOH R 5 .   ? 36.78909  -20.74861 -25.14678 1.000 44.14423 ? 539 HOH B O   1 
HETATM 8718 O  O   . HOH R 5 .   ? 30.19078  26.83223  -28.04091 1.000 42.28563 ? 540 HOH B O   1 
HETATM 8719 O  O   . HOH R 5 .   ? 30.64720  27.14613  -19.21061 1.000 53.22673 ? 541 HOH B O   1 
HETATM 8720 O  O   . HOH R 5 .   ? 30.98588  27.45202  -30.41600 1.000 42.62545 ? 542 HOH B O   1 
HETATM 8721 O  O   . HOH R 5 .   ? 18.84405  15.82906  -51.14883 1.000 60.23446 ? 543 HOH B O   1 
HETATM 8722 O  O   . HOH S 5 .   ? -14.76902 -14.63000 0.89953   1.000 55.73946 ? 401 HOH C O   1 
HETATM 8723 O  O   . HOH S 5 .   ? -5.94214  -7.58970  -11.47689 1.000 35.66023 ? 402 HOH C O   1 
HETATM 8724 O  O   . HOH S 5 .   ? 2.13138   13.82362  -38.09491 1.000 44.80175 ? 403 HOH C O   1 
HETATM 8725 O  O   . HOH S 5 .   ? 3.74556   3.99487   -39.14789 1.000 43.41285 ? 404 HOH C O   1 
HETATM 8726 O  O   . HOH S 5 .   ? 5.61443   -11.53701 -49.31521 1.000 49.50707 ? 405 HOH C O   1 
HETATM 8727 O  O   . HOH S 5 .   ? 11.20782  3.59811   -36.18059 1.000 44.02667 ? 406 HOH C O   1 
HETATM 8728 O  O   . HOH S 5 .   ? 21.31482  33.32363  -24.99132 1.000 39.07827 ? 407 HOH C O   1 
HETATM 8729 O  O   . HOH S 5 .   ? 4.96980   11.09942  -40.46831 1.000 40.33361 ? 408 HOH C O   1 
HETATM 8730 O  O   . HOH S 5 .   ? -12.42216 -16.74448 -17.40608 1.000 46.59931 ? 409 HOH C O   1 
HETATM 8731 O  O   . HOH S 5 .   ? 2.88524   32.05521  -28.44435 1.000 36.28689 ? 410 HOH C O   1 
HETATM 8732 O  O   . HOH S 5 .   ? 11.14272  4.98936   -44.74195 1.000 52.17063 ? 411 HOH C O   1 
HETATM 8733 O  O   . HOH S 5 .   ? -16.44381 -5.87497  -19.97989 1.000 41.74817 ? 412 HOH C O   1 
HETATM 8734 O  O   . HOH S 5 .   ? -8.48009  -1.39351  -42.17783 1.000 50.30539 ? 413 HOH C O   1 
HETATM 8735 O  O   . HOH S 5 .   ? -7.61978  24.85168  -28.57890 1.000 36.35398 ? 414 HOH C O   1 
HETATM 8736 O  O   . HOH S 5 .   ? -7.81681  11.81643  -32.98774 1.000 40.02073 ? 415 HOH C O   1 
HETATM 8737 O  O   . HOH S 5 .   ? -12.72687 -21.97341 -14.92463 1.000 50.96826 ? 416 HOH C O   1 
HETATM 8738 O  O   . HOH S 5 .   ? 6.67722   17.48551  -17.15309 1.000 35.18872 ? 417 HOH C O   1 
HETATM 8739 O  O   . HOH S 5 .   ? -13.04663 -6.60458  -9.75047  1.000 32.12917 ? 418 HOH C O   1 
HETATM 8740 O  O   . HOH S 5 .   ? 3.19969   29.29357  -19.53474 1.000 43.19172 ? 419 HOH C O   1 
HETATM 8741 O  O   . HOH S 5 .   ? 10.87687  -15.38690 -31.38853 1.000 34.73867 ? 420 HOH C O   1 
HETATM 8742 O  O   . HOH S 5 .   ? -17.25258 -5.15199  -8.56562  1.000 38.22125 ? 421 HOH C O   1 
HETATM 8743 O  O   . HOH S 5 .   ? 29.38112  17.14588  -41.53399 1.000 35.79049 ? 422 HOH C O   1 
HETATM 8744 O  O   . HOH S 5 .   ? 34.58115  22.64688  -38.64619 1.000 43.68849 ? 423 HOH C O   1 
HETATM 8745 O  O   . HOH S 5 .   ? 14.84846  23.37389  -27.65543 1.000 28.56764 ? 424 HOH C O   1 
HETATM 8746 O  O   . HOH S 5 .   ? 29.03847  22.78949  -43.54733 1.000 43.36580 ? 425 HOH C O   1 
HETATM 8747 O  O   . HOH S 5 .   ? -7.27415  -20.26566 -20.21259 1.000 38.60852 ? 426 HOH C O   1 
HETATM 8748 O  O   . HOH S 5 .   ? -7.99204  19.92022  -27.30335 1.000 40.44612 ? 427 HOH C O   1 
HETATM 8749 O  O   . HOH S 5 .   ? -4.57860  14.17588  -39.11293 1.000 42.88375 ? 428 HOH C O   1 
HETATM 8750 O  O   . HOH S 5 .   ? 28.49948  35.85652  -26.41667 1.000 52.52984 ? 429 HOH C O   1 
HETATM 8751 O  O   . HOH S 5 .   ? 11.04434  28.12527  -37.78637 1.000 40.41625 ? 430 HOH C O   1 
HETATM 8752 O  O   . HOH S 5 .   ? 12.29827  35.65926  -27.01316 1.000 40.30178 ? 431 HOH C O   1 
HETATM 8753 O  O   . HOH S 5 .   ? 8.21767   -7.34280  -50.37420 1.000 45.17029 ? 432 HOH C O   1 
HETATM 8754 O  O   . HOH S 5 .   ? 12.38152  -17.68937 -33.34454 1.000 37.11743 ? 433 HOH C O   1 
HETATM 8755 O  O   . HOH S 5 .   ? 3.14402   -2.33125  -27.38787 1.000 29.33207 ? 434 HOH C O   1 
HETATM 8756 O  O   . HOH S 5 .   ? 15.10015  -10.38716 -44.94838 1.000 47.43955 ? 435 HOH C O   1 
HETATM 8757 O  O   . HOH S 5 .   ? 8.80952   14.04553  -23.07462 1.000 36.87779 ? 436 HOH C O   1 
HETATM 8758 O  O   . HOH S 5 .   ? 31.54165  15.71355  -42.01074 1.000 43.76166 ? 437 HOH C O   1 
HETATM 8759 O  O   . HOH S 5 .   ? 11.19157  -5.79057  -29.31544 1.000 31.99274 ? 438 HOH C O   1 
HETATM 8760 O  O   . HOH S 5 .   ? -3.11543  -23.83910 -35.01021 1.000 38.91821 ? 439 HOH C O   1 
HETATM 8761 O  O   . HOH S 5 .   ? -2.65503  -25.44808 -3.22734  1.000 39.01861 ? 440 HOH C O   1 
HETATM 8762 O  O   . HOH S 5 .   ? -2.95549  -8.20509  -49.28858 1.000 53.63382 ? 441 HOH C O   1 
HETATM 8763 O  O   . HOH S 5 .   ? 10.98666  -9.29572  -19.24999 1.000 33.38556 ? 442 HOH C O   1 
HETATM 8764 O  O   . HOH S 5 .   ? -7.86871  -6.00287  -38.22072 1.000 35.68293 ? 443 HOH C O   1 
HETATM 8765 O  O   . HOH S 5 .   ? 14.48839  25.11761  -39.16229 1.000 32.21363 ? 444 HOH C O   1 
HETATM 8766 O  O   . HOH S 5 .   ? -17.76071 0.68692   -17.43671 1.000 40.49854 ? 445 HOH C O   1 
HETATM 8767 O  O   . HOH S 5 .   ? -7.95079  8.45295   -21.71742 1.000 34.02268 ? 446 HOH C O   1 
HETATM 8768 O  O   . HOH S 5 .   ? 10.78517  37.06721  -20.55874 1.000 40.73436 ? 447 HOH C O   1 
HETATM 8769 O  O   . HOH S 5 .   ? 33.22454  25.97382  -37.17474 1.000 46.83742 ? 448 HOH C O   1 
HETATM 8770 O  O   . HOH S 5 .   ? -4.70673  -23.42599 -11.95853 1.000 38.06513 ? 449 HOH C O   1 
HETATM 8771 O  O   . HOH S 5 .   ? -0.76922  -16.57069 -21.19941 1.000 28.56815 ? 450 HOH C O   1 
HETATM 8772 O  O   . HOH S 5 .   ? 11.00082  19.78966  -21.79485 1.000 31.40077 ? 451 HOH C O   1 
HETATM 8773 O  O   . HOH S 5 .   ? -13.10123 -11.98910 -18.64300 1.000 40.56314 ? 452 HOH C O   1 
HETATM 8774 O  O   . HOH S 5 .   ? -9.23062  -4.73730  -41.64374 1.000 45.94474 ? 453 HOH C O   1 
HETATM 8775 O  O   . HOH S 5 .   ? 5.247     -27.949   -34.814   1.000 31.82190 ? 454 HOH C O   1 
HETATM 8776 O  O   . HOH S 5 .   ? 19.71966  22.18597  -29.11383 1.000 29.18364 ? 455 HOH C O   1 
HETATM 8777 O  O   . HOH S 5 .   ? 20.96333  22.45060  -21.72959 1.000 31.12125 ? 456 HOH C O   1 
HETATM 8778 O  O   . HOH S 5 .   ? 16.44669  27.58363  -22.63080 1.000 33.13223 ? 457 HOH C O   1 
HETATM 8779 O  O   . HOH S 5 .   ? 31.74402  22.61746  -45.29946 1.000 53.79768 ? 458 HOH C O   1 
HETATM 8780 O  O   . HOH S 5 .   ? -4.50826  -18.42703 -22.66505 1.000 32.07266 ? 459 HOH C O   1 
HETATM 8781 O  O   . HOH S 5 .   ? 19.98074  24.21711  -19.60065 1.000 31.44631 ? 460 HOH C O   1 
HETATM 8782 O  O   . HOH S 5 .   ? -9.42523  -17.69195 -39.84171 1.000 54.23053 ? 461 HOH C O   1 
HETATM 8783 O  O   . HOH S 5 .   ? 10.36128  18.66180  -19.15595 1.000 35.57577 ? 462 HOH C O   1 
HETATM 8784 O  O   . HOH S 5 .   ? 6.88478   -1.68093  -36.60493 1.000 29.08313 ? 463 HOH C O   1 
HETATM 8785 O  O   . HOH S 5 .   ? -10.18024 13.01640  -16.82562 1.000 33.01763 ? 464 HOH C O   1 
HETATM 8786 O  O   . HOH S 5 .   ? -8.63546  11.04150  -26.04288 1.000 38.70319 ? 465 HOH C O   1 
HETATM 8787 O  O   . HOH S 5 .   ? -1.47370  27.28627  -31.20114 1.000 33.21860 ? 466 HOH C O   1 
HETATM 8788 O  O   . HOH S 5 .   ? -6.46274  -4.26035  -44.48652 1.000 55.14676 ? 467 HOH C O   1 
HETATM 8789 O  O   . HOH S 5 .   ? -15.16539 6.57701   -11.48785 1.000 41.81294 ? 468 HOH C O   1 
HETATM 8790 O  O   . HOH S 5 .   ? 23.46958  30.36237  -20.50888 1.000 38.27256 ? 469 HOH C O   1 
HETATM 8791 O  O   . HOH S 5 .   ? 20.17025  26.93795  -22.37598 1.000 34.28720 ? 470 HOH C O   1 
HETATM 8792 O  O   . HOH S 5 .   ? 13.89431  -13.00801 -38.91769 1.000 31.92423 ? 471 HOH C O   1 
HETATM 8793 O  O   . HOH S 5 .   ? 18.06731  19.11279  -29.44097 1.000 32.73353 ? 472 HOH C O   1 
HETATM 8794 O  O   . HOH S 5 .   ? -15.40412 -9.25996  -23.18468 1.000 41.68077 ? 473 HOH C O   1 
HETATM 8795 O  O   . HOH S 5 .   ? -4.43100  22.35401  -33.90964 1.000 37.05436 ? 474 HOH C O   1 
HETATM 8796 O  O   . HOH S 5 .   ? 4.04273   4.53448   -28.44706 1.000 29.86079 ? 475 HOH C O   1 
HETATM 8797 O  O   . HOH S 5 .   ? 10.36010  -7.98533  -21.40267 1.000 37.86509 ? 476 HOH C O   1 
HETATM 8798 O  O   . HOH S 5 .   ? 14.38954  34.64648  -28.50351 1.000 34.01318 ? 477 HOH C O   1 
HETATM 8799 O  O   . HOH S 5 .   ? 4.09447   -21.83648 -23.67984 1.000 29.87761 ? 478 HOH C O   1 
HETATM 8800 O  O   . HOH S 5 .   ? -4.16233  -21.11142 -41.59898 1.000 45.84221 ? 479 HOH C O   1 
HETATM 8801 O  O   . HOH S 5 .   ? 13.29174  -7.07403  -26.20431 1.000 38.03548 ? 480 HOH C O   1 
HETATM 8802 O  O   . HOH S 5 .   ? 12.19938  9.45115   -25.63414 1.000 38.34245 ? 481 HOH C O   1 
HETATM 8803 O  O   . HOH S 5 .   ? 9.32073   -5.51442  -21.11194 1.000 30.16904 ? 482 HOH C O   1 
HETATM 8804 O  O   . HOH S 5 .   ? -3.33702  18.88969  -14.54000 1.000 31.21784 ? 483 HOH C O   1 
HETATM 8805 O  O   . HOH S 5 .   ? -9.99804  17.99489  -27.37873 1.000 42.55330 ? 484 HOH C O   1 
HETATM 8806 O  O   . HOH S 5 .   ? -4.91640  -13.30808 -17.66640 1.000 36.19982 ? 485 HOH C O   1 
HETATM 8807 O  O   . HOH S 5 .   ? 16.21648  14.51409  -38.88083 1.000 31.41505 ? 486 HOH C O   1 
HETATM 8808 O  O   . HOH S 5 .   ? 13.52839  19.54248  -21.80251 1.000 28.28953 ? 487 HOH C O   1 
HETATM 8809 O  O   . HOH S 5 .   ? -5.70800  21.96733  -21.89660 1.000 33.32801 ? 488 HOH C O   1 
HETATM 8810 O  O   . HOH S 5 .   ? -11.12596 -18.44707 -3.47063  1.000 43.95628 ? 489 HOH C O   1 
HETATM 8811 O  O   . HOH S 5 .   ? 1.00319   -18.32268 -39.91844 1.000 36.34439 ? 490 HOH C O   1 
HETATM 8812 O  O   . HOH S 5 .   ? 16.57084  18.72779  -22.90877 1.000 36.34548 ? 491 HOH C O   1 
HETATM 8813 O  O   . HOH S 5 .   ? -5.00186  29.85411  -30.72904 1.000 45.39313 ? 492 HOH C O   1 
HETATM 8814 O  O   . HOH S 5 .   ? -10.45341 -17.84704 -27.82203 1.000 44.72176 ? 493 HOH C O   1 
HETATM 8815 O  O   . HOH S 5 .   ? 14.67303  4.22358   -45.20825 1.000 55.20851 ? 494 HOH C O   1 
HETATM 8816 O  O   . HOH S 5 .   ? -5.91892  -18.32926 -32.54769 1.000 41.30123 ? 495 HOH C O   1 
HETATM 8817 O  O   . HOH S 5 .   ? 7.13395   4.80825   -18.46696 1.000 30.78781 ? 496 HOH C O   1 
HETATM 8818 O  O   . HOH S 5 .   ? 10.71569  -1.71406  -46.70528 1.000 42.68844 ? 497 HOH C O   1 
HETATM 8819 O  O   . HOH S 5 .   ? -9.94921  -20.67733 -36.91669 1.000 51.35487 ? 498 HOH C O   1 
HETATM 8820 O  O   . HOH S 5 .   ? 14.72728  2.79200   -39.16729 1.000 44.06534 ? 499 HOH C O   1 
HETATM 8821 O  O   . HOH S 5 .   ? 5.98721   -0.00496  -38.72234 1.000 39.87461 ? 500 HOH C O   1 
HETATM 8822 O  O   . HOH S 5 .   ? -4.05645  25.31941  -33.45319 1.000 43.62641 ? 501 HOH C O   1 
HETATM 8823 O  O   . HOH S 5 .   ? -17.80333 -2.61323  -9.32630  1.000 42.33133 ? 502 HOH C O   1 
HETATM 8824 O  O   . HOH S 5 .   ? 8.32895   10.73955  -40.88225 1.000 40.90379 ? 503 HOH C O   1 
HETATM 8825 O  O   . HOH S 5 .   ? 28.29652  27.56431  -37.10055 1.000 41.34304 ? 504 HOH C O   1 
HETATM 8826 O  O   . HOH S 5 .   ? 12.16169  -7.40925  -44.44176 1.000 46.56620 ? 505 HOH C O   1 
HETATM 8827 O  O   . HOH S 5 .   ? 27.46238  27.12940  -27.61450 1.000 33.84313 ? 506 HOH C O   1 
HETATM 8828 O  O   . HOH S 5 .   ? 10.44745  -16.45658 -20.89569 1.000 32.24477 ? 507 HOH C O   1 
HETATM 8829 O  O   . HOH S 5 .   ? -5.67988  30.45007  -20.77568 1.000 50.60837 ? 508 HOH C O   1 
HETATM 8830 O  O   . HOH S 5 .   ? -8.37249  -14.12736 -49.27505 1.000 58.73529 ? 509 HOH C O   1 
HETATM 8831 O  O   . HOH S 5 .   ? 25.60462  25.63820  -17.42198 1.000 33.24501 ? 510 HOH C O   1 
HETATM 8832 O  O   . HOH S 5 .   ? -16.06213 -14.29468 -25.63339 1.000 51.27118 ? 511 HOH C O   1 
HETATM 8833 O  O   . HOH S 5 .   ? -7.46018  26.02866  -26.36317 1.000 40.49145 ? 512 HOH C O   1 
HETATM 8834 O  O   . HOH S 5 .   ? 21.72913  38.32524  -26.51009 1.000 40.41777 ? 513 HOH C O   1 
HETATM 8835 O  O   . HOH S 5 .   ? 15.08755  -1.02654  -38.78345 1.000 40.94971 ? 514 HOH C O   1 
HETATM 8836 O  O   . HOH S 5 .   ? 14.27375  19.71871  -33.73382 1.000 30.31032 ? 515 HOH C O   1 
HETATM 8837 O  O   . HOH S 5 .   ? 29.12159  19.91370  -40.75370 1.000 32.43966 ? 516 HOH C O   1 
HETATM 8838 O  O   . HOH S 5 .   ? -16.90219 -2.25073  -13.54444 1.000 36.34093 ? 517 HOH C O   1 
HETATM 8839 O  O   . HOH S 5 .   ? 26.40407  26.23587  -43.89903 1.000 33.43462 ? 518 HOH C O   1 
HETATM 8840 O  O   . HOH S 5 .   ? -6.01229  20.53886  -19.44232 1.000 30.59320 ? 519 HOH C O   1 
HETATM 8841 O  O   . HOH S 5 .   ? 18.55849  37.08975  -23.23452 1.000 44.20006 ? 520 HOH C O   1 
HETATM 8842 O  O   . HOH S 5 .   ? 12.84130  -15.38666 -25.73221 1.000 39.26307 ? 521 HOH C O   1 
HETATM 8843 O  O   . HOH S 5 .   ? -15.32152 -0.50680  -0.32947  1.000 43.83416 ? 522 HOH C O   1 
HETATM 8844 O  O   . HOH S 5 .   ? 11.20070  -6.07834  -42.65406 1.000 40.59347 ? 523 HOH C O   1 
HETATM 8845 O  O   . HOH S 5 .   ? 11.05255  4.18805   -27.29407 1.000 35.30912 ? 524 HOH C O   1 
HETATM 8846 O  O   . HOH S 5 .   ? 19.81514  26.08123  -33.90461 1.000 29.26381 ? 525 HOH C O   1 
HETATM 8847 O  O   . HOH S 5 .   ? 17.17352  17.26166  -26.82214 1.000 38.13941 ? 526 HOH C O   1 
HETATM 8848 O  O   . HOH S 5 .   ? 26.87957  20.57935  -42.29240 1.000 33.70837 ? 527 HOH C O   1 
HETATM 8849 O  O   . HOH S 5 .   ? 8.42519   35.44996  -26.37204 1.000 49.49331 ? 528 HOH C O   1 
HETATM 8850 O  O   . HOH S 5 .   ? -1.73141  -24.80430 -37.20653 1.000 40.18476 ? 529 HOH C O   1 
HETATM 8851 O  O   . HOH S 5 .   ? -14.25380 -19.51744 -18.24903 1.000 43.95631 ? 530 HOH C O   1 
HETATM 8852 O  O   . HOH S 5 .   ? 13.75240  27.65986  -38.18754 1.000 30.37098 ? 531 HOH C O   1 
HETATM 8853 O  O   . HOH S 5 .   ? 26.37247  31.50828  -29.23214 1.000 39.18982 ? 532 HOH C O   1 
HETATM 8854 O  O   . HOH S 5 .   ? 2.04660   15.51510  -16.47997 1.000 33.11611 ? 533 HOH C O   1 
HETATM 8855 O  O   . HOH S 5 .   ? 17.13857  35.43852  -30.51076 1.000 41.99873 ? 534 HOH C O   1 
HETATM 8856 O  O   . HOH S 5 .   ? 28.38650  32.69348  -28.87135 1.000 48.57856 ? 535 HOH C O   1 
HETATM 8857 O  O   . HOH S 5 .   ? -16.19148 -2.45862  -11.23692 1.000 37.79880 ? 536 HOH C O   1 
HETATM 8858 O  O   . HOH S 5 .   ? -7.33264  -15.72341 -14.64537 1.000 37.85386 ? 537 HOH C O   1 
HETATM 8859 O  O   . HOH S 5 .   ? 14.35779  7.20037   -29.00004 1.000 38.43678 ? 538 HOH C O   1 
HETATM 8860 O  O   . HOH S 5 .   ? -4.60588  -27.84486 -6.71694  1.000 45.46399 ? 539 HOH C O   1 
HETATM 8861 O  O   . HOH S 5 .   ? 5.98094   34.30809  -26.00387 1.000 42.14848 ? 540 HOH C O   1 
HETATM 8862 O  O   . HOH S 5 .   ? 25.45888  17.22675  -50.15376 1.000 53.45031 ? 541 HOH C O   1 
HETATM 8863 O  O   . HOH S 5 .   ? -0.21391  10.77972  -40.93337 1.000 51.53018 ? 542 HOH C O   1 
HETATM 8864 O  O   . HOH S 5 .   ? -11.45843 6.66592   -12.20400 1.000 39.05678 ? 543 HOH C O   1 
HETATM 8865 O  O   . HOH S 5 .   ? 17.423    22.118    -45.894   1.000 48.87524 ? 544 HOH C O   1 
HETATM 8866 O  O   . HOH S 5 .   ? -4.45309  28.94623  -32.85862 1.000 46.91543 ? 545 HOH C O   1 
HETATM 8867 O  O   . HOH S 5 .   ? -17.41681 6.30068   -12.46857 1.000 47.05465 ? 546 HOH C O   1 
HETATM 8868 O  O   . HOH S 5 .   ? 11.63752  0.49197   -45.97470 1.000 50.29405 ? 547 HOH C O   1 
HETATM 8869 O  O   . HOH S 5 .   ? -1.34740  -25.57299 -5.09454  1.000 42.21560 ? 548 HOH C O   1 
HETATM 8870 O  O   . HOH S 5 .   ? 26.78873  28.84518  -29.50872 1.000 36.00382 ? 549 HOH C O   1 
HETATM 8871 O  O   . HOH S 5 .   ? 2.87744   13.45089  -41.01582 1.000 53.07246 ? 550 HOH C O   1 
HETATM 8872 O  O   . HOH S 5 .   ? -19.91778 4.04251   -17.76562 1.000 52.18238 ? 551 HOH C O   1 
HETATM 8873 O  O   . HOH S 5 .   ? -10.42055 17.16217  -21.69941 1.000 44.27592 ? 552 HOH C O   1 
HETATM 8874 O  O   . HOH S 5 .   ? -6.26358  -2.52663  -42.75524 1.000 48.48768 ? 553 HOH C O   1 
HETATM 8875 O  O   . HOH S 5 .   ? -9.20079  18.09589  -23.76152 1.000 48.03374 ? 554 HOH C O   1 
HETATM 8876 O  O   . HOH S 5 .   ? 9.607     31.347    -38.971   1.000 50.43569 ? 555 HOH C O   1 
HETATM 8877 O  O   . HOH S 5 .   ? 14.29184  -7.82043  -46.23963 1.000 44.04719 ? 556 HOH C O   1 
HETATM 8878 O  O   . HOH S 5 .   ? 20.99995  38.30538  -24.47176 1.000 48.10549 ? 557 HOH C O   1 
HETATM 8879 O  O   . HOH S 5 .   ? 5.45915   35.12606  -23.74414 1.000 44.94632 ? 558 HOH C O   1 
HETATM 8880 O  O   . HOH S 5 .   ? -9.08658  -15.38214 -31.21823 1.000 43.55284 ? 559 HOH C O   1 
HETATM 8881 O  O   . HOH S 5 .   ? -1.54522  -25.30165 -30.30157 1.000 37.85922 ? 560 HOH C O   1 
HETATM 8882 O  O   . HOH S 5 .   ? -8.77630  21.98872  -28.72024 1.000 42.19978 ? 561 HOH C O   1 
HETATM 8883 O  O   . HOH S 5 .   ? 28.97989  28.01702  -21.10280 1.000 51.71343 ? 562 HOH C O   1 
HETATM 8884 O  O   . HOH S 5 .   ? -2.34261  -26.00223 -33.16563 1.000 44.08943 ? 563 HOH C O   1 
HETATM 8885 O  O   . HOH S 5 .   ? 18.38062  40.45704  -24.13622 1.000 50.63385 ? 564 HOH C O   1 
HETATM 8886 O  O   . HOH S 5 .   ? 29.42135  28.83385  -30.64971 1.000 44.26225 ? 565 HOH C O   1 
HETATM 8887 O  O   . HOH S 5 .   ? -4.13873  -27.29509 -32.59581 1.000 54.22300 ? 566 HOH C O   1 
HETATM 8888 O  O   . HOH T 5 .   ? 5.19987   1.27868   9.17613   1.000 53.83706 ? 401 HOH D O   1 
HETATM 8889 O  O   . HOH T 5 .   ? -7.24335  11.82008  4.88089   1.000 45.06227 ? 402 HOH D O   1 
HETATM 8890 O  O   . HOH T 5 .   ? -15.27318 -6.05325  -31.91095 1.000 45.13335 ? 403 HOH D O   1 
HETATM 8891 O  O   . HOH T 5 .   ? 12.00343  -32.42482 -8.55437  1.000 37.48406 ? 404 HOH D O   1 
HETATM 8892 O  O   . HOH T 5 .   ? -2.78068  -18.72171 0.03831   1.000 37.55185 ? 405 HOH D O   1 
HETATM 8893 O  O   . HOH T 5 .   ? -15.71207 9.12389   -22.99720 1.000 42.75573 ? 406 HOH D O   1 
HETATM 8894 O  O   . HOH T 5 .   ? 5.44929   5.83539   5.52171   1.000 51.66224 ? 407 HOH D O   1 
HETATM 8895 O  O   . HOH T 5 .   ? -0.36266  -29.17534 -10.26774 1.000 37.83429 ? 408 HOH D O   1 
HETATM 8896 O  O   . HOH T 5 .   ? -6.20785  2.53937   -27.67021 1.000 38.02903 ? 409 HOH D O   1 
HETATM 8897 O  O   . HOH T 5 .   ? -10.41548 19.10617  -38.54412 1.000 53.95575 ? 410 HOH D O   1 
HETATM 8898 O  O   . HOH T 5 .   ? -16.90577 -2.64239  -20.91310 1.000 39.79835 ? 411 HOH D O   1 
HETATM 8899 O  O   . HOH T 5 .   ? 2.74047   13.38942  10.42867  1.000 60.95013 ? 412 HOH D O   1 
HETATM 8900 O  O   . HOH T 5 .   ? -16.60198 16.18399  -17.37412 1.000 47.02901 ? 413 HOH D O   1 
HETATM 8901 O  O   . HOH T 5 .   ? 5.05859   -25.56730 4.64583   1.000 51.40228 ? 414 HOH D O   1 
HETATM 8902 O  O   . HOH T 5 .   ? 1.14155   -14.36785 0.30747   1.000 47.48006 ? 415 HOH D O   1 
HETATM 8903 O  O   . HOH T 5 .   ? -13.73960 -1.83798  1.30357   1.000 44.32660 ? 416 HOH D O   1 
HETATM 8904 O  O   . HOH T 5 .   ? 2.36700   -28.11731 -5.21427  1.000 35.72653 ? 417 HOH D O   1 
HETATM 8905 O  O   . HOH T 5 .   ? 30.35290  -27.91633 -9.21379  1.000 50.18127 ? 418 HOH D O   1 
HETATM 8906 O  O   . HOH T 5 .   ? 24.15063  -23.89471 -11.93314 1.000 39.66714 ? 419 HOH D O   1 
HETATM 8907 O  O   . HOH T 5 .   ? -15.27960 -3.15792  -32.67371 1.000 38.93102 ? 420 HOH D O   1 
HETATM 8908 O  O   . HOH T 5 .   ? -6.34763  24.53829  -3.59576  1.000 41.53706 ? 421 HOH D O   1 
HETATM 8909 O  O   . HOH T 5 .   ? -1.79572  2.95705   5.44211   1.000 54.28074 ? 422 HOH D O   1 
HETATM 8910 O  O   . HOH T 5 .   ? 11.04277  -3.48374  -9.42070  1.000 34.19991 ? 423 HOH D O   1 
HETATM 8911 O  O   . HOH T 5 .   ? -6.88961  -7.03080  1.36376   1.000 47.11382 ? 424 HOH D O   1 
HETATM 8912 O  O   . HOH T 5 .   ? 12.03226  -11.34064 -16.70844 1.000 35.59910 ? 425 HOH D O   1 
HETATM 8913 O  O   . HOH T 5 .   ? -15.83807 4.39219   -21.65932 1.000 40.90548 ? 426 HOH D O   1 
HETATM 8914 O  O   . HOH T 5 .   ? -12.39114 18.22708  -4.51536  1.000 44.19166 ? 427 HOH D O   1 
HETATM 8915 O  O   . HOH T 5 .   ? 3.79640   13.40847  -8.38901  1.000 43.01590 ? 428 HOH D O   1 
HETATM 8916 O  O   . HOH T 5 .   ? 1.49463   0.16273   -10.42877 1.000 29.13060 ? 429 HOH D O   1 
HETATM 8917 O  O   . HOH T 5 .   ? 27.51767  -22.14519 -12.04966 1.000 39.19229 ? 430 HOH D O   1 
HETATM 8918 O  O   . HOH T 5 .   ? -11.90367 -0.16865  -1.72117  1.000 38.89605 ? 431 HOH D O   1 
HETATM 8919 O  O   . HOH T 5 .   ? 12.53670  -17.27916 -19.56627 1.000 33.08197 ? 432 HOH D O   1 
HETATM 8920 O  O   . HOH T 5 .   ? 7.62042   5.77954   -7.06106  1.000 33.58393 ? 433 HOH D O   1 
HETATM 8921 O  O   . HOH T 5 .   ? -18.84649 11.30391  -22.47198 1.000 51.58611 ? 434 HOH D O   1 
HETATM 8922 O  O   . HOH T 5 .   ? 24.43343  -18.13757 -5.39892  1.000 40.45100 ? 435 HOH D O   1 
HETATM 8923 O  O   . HOH T 5 .   ? -5.36767  -17.12665 -6.04963  1.000 34.07538 ? 436 HOH D O   1 
HETATM 8924 O  O   . HOH T 5 .   ? 25.40716  -22.43885 -0.60994  1.000 52.14303 ? 437 HOH D O   1 
HETATM 8925 O  O   . HOH T 5 .   ? 10.07058  0.86731   3.07761   1.000 54.05017 ? 438 HOH D O   1 
HETATM 8926 O  O   . HOH T 5 .   ? -7.93378  14.16714  1.07337   1.000 43.68608 ? 439 HOH D O   1 
HETATM 8927 O  O   . HOH T 5 .   ? -5.70888  12.65619  -17.44522 1.000 29.19701 ? 440 HOH D O   1 
HETATM 8928 O  O   . HOH T 5 .   ? 5.67667   -29.54850 -6.51195  1.000 34.16578 ? 441 HOH D O   1 
HETATM 8929 O  O   . HOH T 5 .   ? 20.61404  -20.67865 -7.41042  1.000 35.18702 ? 442 HOH D O   1 
HETATM 8930 O  O   . HOH T 5 .   ? 12.55945  -3.08523  -15.90328 1.000 37.81186 ? 443 HOH D O   1 
HETATM 8931 O  O   . HOH T 5 .   ? 16.74282  -18.24987 -14.23582 1.000 33.73350 ? 444 HOH D O   1 
HETATM 8932 O  O   . HOH T 5 .   ? -2.14428  -24.49799 -11.65553 1.000 39.54011 ? 445 HOH D O   1 
HETATM 8933 O  O   . HOH T 5 .   ? -19.79504 5.54752   -15.44286 1.000 49.03442 ? 446 HOH D O   1 
HETATM 8934 O  O   . HOH T 5 .   ? -10.10024 -13.78161 -29.02677 1.000 38.63334 ? 447 HOH D O   1 
HETATM 8935 O  O   . HOH T 5 .   ? -9.53017  -13.58418 0.43265   1.000 57.13213 ? 448 HOH D O   1 
HETATM 8936 O  O   . HOH T 5 .   ? -10.26255 -11.43856 -2.76597  1.000 50.52670 ? 449 HOH D O   1 
HETATM 8937 O  O   . HOH T 5 .   ? 21.91337  -15.63040 -5.50771  1.000 41.21001 ? 450 HOH D O   1 
HETATM 8938 O  O   . HOH T 5 .   ? -12.48225 -0.71694  -30.40747 1.000 35.78352 ? 451 HOH D O   1 
HETATM 8939 O  O   . HOH T 5 .   ? 18.96335  -17.25277 -13.58456 1.000 33.07486 ? 452 HOH D O   1 
HETATM 8940 O  O   . HOH T 5 .   ? 8.51428   -32.99325 -1.87316  1.000 41.93736 ? 453 HOH D O   1 
HETATM 8941 O  O   . HOH T 5 .   ? 4.27925   17.24755  -3.56543  1.000 40.47059 ? 454 HOH D O   1 
HETATM 8942 O  O   . HOH T 5 .   ? -12.92662 14.18493  -19.84438 1.000 37.89576 ? 455 HOH D O   1 
HETATM 8943 O  O   . HOH T 5 .   ? 26.72829  -17.78760 -12.76947 1.000 39.24253 ? 456 HOH D O   1 
HETATM 8944 O  O   . HOH T 5 .   ? 8.55988   -18.55515 1.02189   1.000 37.96244 ? 457 HOH D O   1 
HETATM 8945 O  O   . HOH T 5 .   ? 4.64293   15.84899  -16.08644 1.000 32.53430 ? 458 HOH D O   1 
HETATM 8946 O  O   . HOH T 5 .   ? -20.45942 -2.24409  -29.56932 1.000 48.31627 ? 459 HOH D O   1 
HETATM 8947 O  O   . HOH T 5 .   ? 10.21029  -28.22036 -18.53712 1.000 31.39402 ? 460 HOH D O   1 
HETATM 8948 O  O   . HOH T 5 .   ? 3.64350   0.43649   -0.70847  1.000 35.89402 ? 461 HOH D O   1 
HETATM 8949 O  O   . HOH T 5 .   ? 7.59180   -16.96759 -20.96289 1.000 37.24127 ? 462 HOH D O   1 
HETATM 8950 O  O   . HOH T 5 .   ? 0.48409   -30.15222 -12.91639 1.000 39.56577 ? 463 HOH D O   1 
HETATM 8951 O  O   . HOH T 5 .   ? 1.13969   16.88770  -14.64498 1.000 37.85134 ? 464 HOH D O   1 
HETATM 8952 O  O   . HOH T 5 .   ? 8.79501   -5.29099  -18.56717 1.000 30.95948 ? 465 HOH D O   1 
HETATM 8953 O  O   . HOH T 5 .   ? -14.07949 11.41579  -36.71574 1.000 50.43484 ? 466 HOH D O   1 
HETATM 8954 O  O   . HOH T 5 .   ? 26.60054  -19.52447 -14.75108 1.000 35.07377 ? 467 HOH D O   1 
HETATM 8955 O  O   . HOH T 5 .   ? 4.32176   -5.89808  -9.01838  1.000 31.53344 ? 468 HOH D O   1 
HETATM 8956 O  O   . HOH T 5 .   ? -13.17771 15.86197  -21.50837 1.000 46.41226 ? 469 HOH D O   1 
HETATM 8957 O  O   . HOH T 5 .   ? 7.22624   5.18072   -15.58119 1.000 28.55444 ? 470 HOH D O   1 
HETATM 8958 O  O   . HOH T 5 .   ? 14.31963  -21.15658 3.81915   1.000 49.06551 ? 471 HOH D O   1 
HETATM 8959 O  O   . HOH T 5 .   ? -15.05390 -9.64828  -29.52374 1.000 47.72279 ? 472 HOH D O   1 
HETATM 8960 O  O   . HOH T 5 .   ? 8.80957   -10.89891 3.95685   1.000 51.44659 ? 473 HOH D O   1 
HETATM 8961 O  O   . HOH T 5 .   ? 7.28417   7.91653   -15.41769 1.000 39.34315 ? 474 HOH D O   1 
HETATM 8962 O  O   . HOH T 5 .   ? 17.51065  -17.42421 -1.81669  1.000 44.70208 ? 475 HOH D O   1 
HETATM 8963 O  O   . HOH T 5 .   ? 33.60971  -20.02682 -5.69202  1.000 48.04408 ? 476 HOH D O   1 
HETATM 8964 O  O   . HOH T 5 .   ? -11.62876 19.47542  -2.41705  1.000 40.43050 ? 477 HOH D O   1 
HETATM 8965 O  O   . HOH T 5 .   ? -11.00023 -6.80375  -40.02810 1.000 43.59300 ? 478 HOH D O   1 
HETATM 8966 O  O   . HOH T 5 .   ? -5.19635  -16.33141 -13.07974 1.000 34.95028 ? 479 HOH D O   1 
HETATM 8967 O  O   . HOH T 5 .   ? -9.16981  9.77614   5.09943   1.000 48.42959 ? 480 HOH D O   1 
HETATM 8968 O  O   . HOH T 5 .   ? -12.99249 16.74792  -16.46266 1.000 43.86845 ? 481 HOH D O   1 
HETATM 8969 O  O   . HOH T 5 .   ? 6.77923   15.61199  -10.76039 1.000 38.12397 ? 482 HOH D O   1 
HETATM 8970 O  O   . HOH T 5 .   ? 37.14224  -17.58661 4.17962   1.000 63.59948 ? 483 HOH D O   1 
HETATM 8971 O  O   . HOH T 5 .   ? -9.99622  3.65745   -34.88240 1.000 44.78420 ? 484 HOH D O   1 
HETATM 8972 O  O   . HOH T 5 .   ? -14.14385 -5.44560  -29.85051 1.000 36.44886 ? 485 HOH D O   1 
HETATM 8973 O  O   . HOH T 5 .   ? 13.97250  -8.10027  -10.62749 1.000 39.72056 ? 486 HOH D O   1 
HETATM 8974 O  O   . HOH T 5 .   ? 1.21587   -24.21380 -19.16962 1.000 32.49320 ? 487 HOH D O   1 
HETATM 8975 O  O   . HOH T 5 .   ? 1.47449   -25.48099 -16.66106 1.000 32.56345 ? 488 HOH D O   1 
HETATM 8976 O  O   . HOH T 5 .   ? -18.55430 8.50627   -13.27521 1.000 47.32781 ? 489 HOH D O   1 
HETATM 8977 O  O   . HOH T 5 .   ? -13.88754 18.26577  -14.53104 1.000 47.12486 ? 490 HOH D O   1 
HETATM 8978 O  O   . HOH T 5 .   ? -11.66089 -7.16535  -5.08695  1.000 40.62693 ? 491 HOH D O   1 
HETATM 8979 O  O   . HOH T 5 .   ? -7.23125  21.47343  -33.17408 1.000 53.63590 ? 492 HOH D O   1 
HETATM 8980 O  O   . HOH T 5 .   ? -15.07237 -6.04582  -27.08395 1.000 41.22252 ? 493 HOH D O   1 
HETATM 8981 O  O   . HOH T 5 .   ? 0.99724   -26.00194 -4.32824  1.000 35.46476 ? 494 HOH D O   1 
HETATM 8982 O  O   . HOH T 5 .   ? -20.09364 7.30027   -29.68792 1.000 49.86471 ? 495 HOH D O   1 
HETATM 8983 O  O   . HOH T 5 .   ? 33.07719  -19.13481 -16.15720 1.000 38.99660 ? 496 HOH D O   1 
HETATM 8984 O  O   . HOH T 5 .   ? 3.04456   -1.60094  1.15904   1.000 46.43239 ? 497 HOH D O   1 
HETATM 8985 O  O   . HOH T 5 .   ? 28.81478  -14.40369 8.30537   1.000 57.02451 ? 498 HOH D O   1 
HETATM 8986 O  O   . HOH T 5 .   ? -11.05278 -1.74314  4.86184   1.000 51.78574 ? 499 HOH D O   1 
HETATM 8987 O  O   . HOH T 5 .   ? 3.88719   14.81609  -6.10956  1.000 39.40884 ? 500 HOH D O   1 
HETATM 8988 O  O   . HOH T 5 .   ? -10.56593 9.83515   -25.10996 1.000 45.59780 ? 501 HOH D O   1 
HETATM 8989 O  O   . HOH T 5 .   ? 0.47201   -27.56605 -2.10559  1.000 41.85750 ? 502 HOH D O   1 
HETATM 8990 O  O   . HOH T 5 .   ? -7.69701  14.40898  3.90346   1.000 43.12574 ? 503 HOH D O   1 
HETATM 8991 O  O   . HOH T 5 .   ? 20.66309  -32.57073 0.52482   1.000 52.43909 ? 504 HOH D O   1 
HETATM 8992 O  O   . HOH T 5 .   ? -2.91312  -22.78253 -15.04444 1.000 41.59517 ? 505 HOH D O   1 
HETATM 8993 O  O   . HOH T 5 .   ? 33.61157  -22.04894 -3.84916  1.000 55.99329 ? 506 HOH D O   1 
HETATM 8994 O  O   . HOH T 5 .   ? -2.11600  -27.05873 -7.14939  1.000 35.14530 ? 507 HOH D O   1 
HETATM 8995 O  O   . HOH T 5 .   ? -17.40361 6.77840   -22.83532 1.000 44.05199 ? 508 HOH D O   1 
HETATM 8996 O  O   . HOH T 5 .   ? -2.29934  -26.57803 -9.86484  1.000 39.19769 ? 509 HOH D O   1 
HETATM 8997 O  O   . HOH T 5 .   ? -1.10691  -25.62273 -20.53792 1.000 52.25221 ? 510 HOH D O   1 
HETATM 8998 O  O   . HOH T 5 .   ? -15.64583 18.02488  -4.78902  1.000 53.27614 ? 511 HOH D O   1 
# 
