data_9C7L
# 
_entry.id   9C7L 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9C7L         pdb_00009c7l 10.2210/pdb9c7l/pdb 
WWPDB D_1000284960 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-06 
2 'Structure model' 1 1 2024-11-13 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            citation 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume' 
2 2 'Structure model' '_citation.page_first'     
3 2 'Structure model' '_citation.page_last'      
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9C7L 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-10 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              oprian@brandeis.edu 
_pdbx_contact_author.name_first         Daniel 
_pdbx_contact_author.name_last          Oprian 
_pdbx_contact_author.name_mi            D 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6520-5459 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Prem Kumar, R.'  1 ? 
'Ellenburg, W.H.' 2 ? 
'Oprian, D.D.'    3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biochemistry 
_citation.journal_id_ASTM           BICHAW 
_citation.journal_id_CSD            0033 
_citation.journal_id_ISSN           0006-2960 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            63 
_citation.language                  ? 
_citation.page_first                2904 
_citation.page_last                 2915 
_citation.title                     
'Crystal Structure of Caryolan-1-ol Synthase, a Sesquiterpene Synthase Catalyzing an Initial Anti-Markovnikov Cyclization Reaction.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acs.biochem.4c00547 
_citation.pdbx_database_id_PubMed   39400323 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kumar, R.P.'     1  0000-0002-6555-8289 
primary 'Matos, J.O.'     2  ?                   
primary 'Black, B.Y.'     3  ?                   
primary 'Ellenburg, W.H.' 4  0000-0001-5726-1277 
primary 'Chen, J.'        5  0000-0002-7573-6333 
primary 'Patterson, M.'   6  ?                   
primary 'Gehtman, J.A.'   7  ?                   
primary 'Theobald, D.L.'  8  0000-0002-2695-8343 
primary 'Krauss, I.J.'    9  0000-0003-0984-4085 
primary 'Oprian, D.D.'    10 0000-0002-6520-5459 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Pentalenene synthase'                                                              37974.316 2   4.2.3.7 F76A ? 
? 
2 non-polymer syn '(2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate' 400.317   1   ?       ?    ? 
? 
3 non-polymer syn 'MAGNESIUM ION'                                                                     24.305    3   ?       ?    ? 
? 
4 water       nat water                                                                               18.015    336 ?       ?    ? 
? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'PS,Pentalenolactone biosynthesis protein A,Sesquiterpene cyclase,Sesquiterpene synthase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MPQDVDFHIPLPGRQSPDHARAEAEQLAWPRSLGLIRSDAAAERHLRGGYADLASRFYPHATGADLDLGVDLMSWAFLFD
DLFDGPRGENPEDTKQLTDQVAAALDGPLPDTAPPIAHGFADIWRRTCEGMTPAWCARSARHWRNYFDGYVDEAESRFWN
APCDSAAQYLAMRRHTIGVQPTVDLAERAGRFEVPHRVFDSAVMSAMLQIAVDVNLLLNDIASLEKEEARGEQNNMVMIL
RREHGWSKSRSVSHMQNEVRARLEQYLLLESCLPKVGEIYQLDTAEREALERYRTDAVRTVIRGSYDWHRSSGRYDAEFA
LAAGAQGYLEELGSSAH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MPQDVDFHIPLPGRQSPDHARAEAEQLAWPRSLGLIRSDAAAERHLRGGYADLASRFYPHATGADLDLGVDLMSWAFLFD
DLFDGPRGENPEDTKQLTDQVAAALDGPLPDTAPPIAHGFADIWRRTCEGMTPAWCARSARHWRNYFDGYVDEAESRFWN
APCDSAAQYLAMRRHTIGVQPTVDLAERAGRFEVPHRVFDSAVMSAMLQIAVDVNLLLNDIASLEKEEARGEQNNMVMIL
RREHGWSKSRSVSHMQNEVRARLEQYLLLESCLPKVGEIYQLDTAEREALERYRTDAVRTVIRGSYDWHRSSGRYDAEFA
LAAGAQGYLEELGSSAH
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '(2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate' FPF 
3 'MAGNESIUM ION'                                                                     MG  
4 water                                                                               HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   PRO n 
1 3   GLN n 
1 4   ASP n 
1 5   VAL n 
1 6   ASP n 
1 7   PHE n 
1 8   HIS n 
1 9   ILE n 
1 10  PRO n 
1 11  LEU n 
1 12  PRO n 
1 13  GLY n 
1 14  ARG n 
1 15  GLN n 
1 16  SER n 
1 17  PRO n 
1 18  ASP n 
1 19  HIS n 
1 20  ALA n 
1 21  ARG n 
1 22  ALA n 
1 23  GLU n 
1 24  ALA n 
1 25  GLU n 
1 26  GLN n 
1 27  LEU n 
1 28  ALA n 
1 29  TRP n 
1 30  PRO n 
1 31  ARG n 
1 32  SER n 
1 33  LEU n 
1 34  GLY n 
1 35  LEU n 
1 36  ILE n 
1 37  ARG n 
1 38  SER n 
1 39  ASP n 
1 40  ALA n 
1 41  ALA n 
1 42  ALA n 
1 43  GLU n 
1 44  ARG n 
1 45  HIS n 
1 46  LEU n 
1 47  ARG n 
1 48  GLY n 
1 49  GLY n 
1 50  TYR n 
1 51  ALA n 
1 52  ASP n 
1 53  LEU n 
1 54  ALA n 
1 55  SER n 
1 56  ARG n 
1 57  PHE n 
1 58  TYR n 
1 59  PRO n 
1 60  HIS n 
1 61  ALA n 
1 62  THR n 
1 63  GLY n 
1 64  ALA n 
1 65  ASP n 
1 66  LEU n 
1 67  ASP n 
1 68  LEU n 
1 69  GLY n 
1 70  VAL n 
1 71  ASP n 
1 72  LEU n 
1 73  MET n 
1 74  SER n 
1 75  TRP n 
1 76  ALA n 
1 77  PHE n 
1 78  LEU n 
1 79  PHE n 
1 80  ASP n 
1 81  ASP n 
1 82  LEU n 
1 83  PHE n 
1 84  ASP n 
1 85  GLY n 
1 86  PRO n 
1 87  ARG n 
1 88  GLY n 
1 89  GLU n 
1 90  ASN n 
1 91  PRO n 
1 92  GLU n 
1 93  ASP n 
1 94  THR n 
1 95  LYS n 
1 96  GLN n 
1 97  LEU n 
1 98  THR n 
1 99  ASP n 
1 100 GLN n 
1 101 VAL n 
1 102 ALA n 
1 103 ALA n 
1 104 ALA n 
1 105 LEU n 
1 106 ASP n 
1 107 GLY n 
1 108 PRO n 
1 109 LEU n 
1 110 PRO n 
1 111 ASP n 
1 112 THR n 
1 113 ALA n 
1 114 PRO n 
1 115 PRO n 
1 116 ILE n 
1 117 ALA n 
1 118 HIS n 
1 119 GLY n 
1 120 PHE n 
1 121 ALA n 
1 122 ASP n 
1 123 ILE n 
1 124 TRP n 
1 125 ARG n 
1 126 ARG n 
1 127 THR n 
1 128 CYS n 
1 129 GLU n 
1 130 GLY n 
1 131 MET n 
1 132 THR n 
1 133 PRO n 
1 134 ALA n 
1 135 TRP n 
1 136 CYS n 
1 137 ALA n 
1 138 ARG n 
1 139 SER n 
1 140 ALA n 
1 141 ARG n 
1 142 HIS n 
1 143 TRP n 
1 144 ARG n 
1 145 ASN n 
1 146 TYR n 
1 147 PHE n 
1 148 ASP n 
1 149 GLY n 
1 150 TYR n 
1 151 VAL n 
1 152 ASP n 
1 153 GLU n 
1 154 ALA n 
1 155 GLU n 
1 156 SER n 
1 157 ARG n 
1 158 PHE n 
1 159 TRP n 
1 160 ASN n 
1 161 ALA n 
1 162 PRO n 
1 163 CYS n 
1 164 ASP n 
1 165 SER n 
1 166 ALA n 
1 167 ALA n 
1 168 GLN n 
1 169 TYR n 
1 170 LEU n 
1 171 ALA n 
1 172 MET n 
1 173 ARG n 
1 174 ARG n 
1 175 HIS n 
1 176 THR n 
1 177 ILE n 
1 178 GLY n 
1 179 VAL n 
1 180 GLN n 
1 181 PRO n 
1 182 THR n 
1 183 VAL n 
1 184 ASP n 
1 185 LEU n 
1 186 ALA n 
1 187 GLU n 
1 188 ARG n 
1 189 ALA n 
1 190 GLY n 
1 191 ARG n 
1 192 PHE n 
1 193 GLU n 
1 194 VAL n 
1 195 PRO n 
1 196 HIS n 
1 197 ARG n 
1 198 VAL n 
1 199 PHE n 
1 200 ASP n 
1 201 SER n 
1 202 ALA n 
1 203 VAL n 
1 204 MET n 
1 205 SER n 
1 206 ALA n 
1 207 MET n 
1 208 LEU n 
1 209 GLN n 
1 210 ILE n 
1 211 ALA n 
1 212 VAL n 
1 213 ASP n 
1 214 VAL n 
1 215 ASN n 
1 216 LEU n 
1 217 LEU n 
1 218 LEU n 
1 219 ASN n 
1 220 ASP n 
1 221 ILE n 
1 222 ALA n 
1 223 SER n 
1 224 LEU n 
1 225 GLU n 
1 226 LYS n 
1 227 GLU n 
1 228 GLU n 
1 229 ALA n 
1 230 ARG n 
1 231 GLY n 
1 232 GLU n 
1 233 GLN n 
1 234 ASN n 
1 235 ASN n 
1 236 MET n 
1 237 VAL n 
1 238 MET n 
1 239 ILE n 
1 240 LEU n 
1 241 ARG n 
1 242 ARG n 
1 243 GLU n 
1 244 HIS n 
1 245 GLY n 
1 246 TRP n 
1 247 SER n 
1 248 LYS n 
1 249 SER n 
1 250 ARG n 
1 251 SER n 
1 252 VAL n 
1 253 SER n 
1 254 HIS n 
1 255 MET n 
1 256 GLN n 
1 257 ASN n 
1 258 GLU n 
1 259 VAL n 
1 260 ARG n 
1 261 ALA n 
1 262 ARG n 
1 263 LEU n 
1 264 GLU n 
1 265 GLN n 
1 266 TYR n 
1 267 LEU n 
1 268 LEU n 
1 269 LEU n 
1 270 GLU n 
1 271 SER n 
1 272 CYS n 
1 273 LEU n 
1 274 PRO n 
1 275 LYS n 
1 276 VAL n 
1 277 GLY n 
1 278 GLU n 
1 279 ILE n 
1 280 TYR n 
1 281 GLN n 
1 282 LEU n 
1 283 ASP n 
1 284 THR n 
1 285 ALA n 
1 286 GLU n 
1 287 ARG n 
1 288 GLU n 
1 289 ALA n 
1 290 LEU n 
1 291 GLU n 
1 292 ARG n 
1 293 TYR n 
1 294 ARG n 
1 295 THR n 
1 296 ASP n 
1 297 ALA n 
1 298 VAL n 
1 299 ARG n 
1 300 THR n 
1 301 VAL n 
1 302 ILE n 
1 303 ARG n 
1 304 GLY n 
1 305 SER n 
1 306 TYR n 
1 307 ASP n 
1 308 TRP n 
1 309 HIS n 
1 310 ARG n 
1 311 SER n 
1 312 SER n 
1 313 GLY n 
1 314 ARG n 
1 315 TYR n 
1 316 ASP n 
1 317 ALA n 
1 318 GLU n 
1 319 PHE n 
1 320 ALA n 
1 321 LEU n 
1 322 ALA n 
1 323 ALA n 
1 324 GLY n 
1 325 ALA n 
1 326 GLN n 
1 327 GLY n 
1 328 TYR n 
1 329 LEU n 
1 330 GLU n 
1 331 GLU n 
1 332 LEU n 
1 333 GLY n 
1 334 SER n 
1 335 SER n 
1 336 ALA n 
1 337 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   337 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 penA 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Streptomyces exfoliatus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1905 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                                             ? 'C3 H7 N O2'      
89.093  
ARG 'L-peptide linking' y ARGININE                                                                            ? 'C6 H15 N4 O2 1'  
175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                                          ? 'C4 H8 N2 O3'     
132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                                     ? 'C4 H7 N O4'      
133.103 
CYS 'L-peptide linking' y CYSTEINE                                                                            ? 'C3 H7 N O2 S'    
121.158 
FPF non-polymer         . '(2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate' ? 'C15 H27 F O7 P2' 
400.317 
GLN 'L-peptide linking' y GLUTAMINE                                                                           ? 'C5 H10 N2 O3'    
146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                                     ? 'C5 H9 N O4'      
147.129 
GLY 'peptide linking'   y GLYCINE                                                                             ? 'C2 H5 N O2'      
75.067  
HIS 'L-peptide linking' y HISTIDINE                                                                           ? 'C6 H10 N3 O2 1'  
156.162 
HOH non-polymer         . WATER                                                                               ? 'H2 O'            
18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                                                          ? 'C6 H13 N O2'     
131.173 
LEU 'L-peptide linking' y LEUCINE                                                                             ? 'C6 H13 N O2'     
131.173 
LYS 'L-peptide linking' y LYSINE                                                                              ? 'C6 H15 N2 O2 1'  
147.195 
MET 'L-peptide linking' y METHIONINE                                                                          ? 'C5 H11 N O2 S'   
149.211 
MG  non-polymer         . 'MAGNESIUM ION'                                                                     ? 'Mg 2'            
24.305  
PHE 'L-peptide linking' y PHENYLALANINE                                                                       ? 'C9 H11 N O2'     
165.189 
PRO 'L-peptide linking' y PROLINE                                                                             ? 'C5 H9 N O2'      
115.130 
SER 'L-peptide linking' y SERINE                                                                              ? 'C3 H7 N O3'      
105.093 
THR 'L-peptide linking' y THREONINE                                                                           ? 'C4 H9 N O3'      
119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                                          ? 'C11 H12 N2 O2'   
204.225 
TYR 'L-peptide linking' y TYROSINE                                                                            ? 'C9 H11 N O3'     
181.189 
VAL 'L-peptide linking' y VALINE                                                                              ? 'C5 H11 N O2'     
117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   PRO 2   2   ?   ?   ?   A . n 
A 1 3   GLN 3   3   ?   ?   ?   A . n 
A 1 4   ASP 4   4   4   ASP ASP A . n 
A 1 5   VAL 5   5   5   VAL VAL A . n 
A 1 6   ASP 6   6   6   ASP ASP A . n 
A 1 7   PHE 7   7   7   PHE PHE A . n 
A 1 8   HIS 8   8   8   HIS HIS A . n 
A 1 9   ILE 9   9   9   ILE ILE A . n 
A 1 10  PRO 10  10  10  PRO PRO A . n 
A 1 11  LEU 11  11  11  LEU LEU A . n 
A 1 12  PRO 12  12  12  PRO PRO A . n 
A 1 13  GLY 13  13  13  GLY GLY A . n 
A 1 14  ARG 14  14  14  ARG ARG A . n 
A 1 15  GLN 15  15  15  GLN GLN A . n 
A 1 16  SER 16  16  16  SER SER A . n 
A 1 17  PRO 17  17  17  PRO PRO A . n 
A 1 18  ASP 18  18  18  ASP ASP A . n 
A 1 19  HIS 19  19  19  HIS HIS A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  ARG 21  21  21  ARG ARG A . n 
A 1 22  ALA 22  22  22  ALA ALA A . n 
A 1 23  GLU 23  23  23  GLU GLU A . n 
A 1 24  ALA 24  24  24  ALA ALA A . n 
A 1 25  GLU 25  25  25  GLU GLU A . n 
A 1 26  GLN 26  26  26  GLN GLN A . n 
A 1 27  LEU 27  27  27  LEU LEU A . n 
A 1 28  ALA 28  28  28  ALA ALA A . n 
A 1 29  TRP 29  29  29  TRP TRP A . n 
A 1 30  PRO 30  30  30  PRO PRO A . n 
A 1 31  ARG 31  31  31  ARG ARG A . n 
A 1 32  SER 32  32  32  SER SER A . n 
A 1 33  LEU 33  33  33  LEU LEU A . n 
A 1 34  GLY 34  34  34  GLY GLY A . n 
A 1 35  LEU 35  35  35  LEU LEU A . n 
A 1 36  ILE 36  36  36  ILE ILE A . n 
A 1 37  ARG 37  37  37  ARG ARG A . n 
A 1 38  SER 38  38  38  SER SER A . n 
A 1 39  ASP 39  39  39  ASP ASP A . n 
A 1 40  ALA 40  40  40  ALA ALA A . n 
A 1 41  ALA 41  41  41  ALA ALA A . n 
A 1 42  ALA 42  42  42  ALA ALA A . n 
A 1 43  GLU 43  43  43  GLU GLU A . n 
A 1 44  ARG 44  44  44  ARG ARG A . n 
A 1 45  HIS 45  45  45  HIS HIS A . n 
A 1 46  LEU 46  46  46  LEU LEU A . n 
A 1 47  ARG 47  47  47  ARG ARG A . n 
A 1 48  GLY 48  48  48  GLY GLY A . n 
A 1 49  GLY 49  49  49  GLY GLY A . n 
A 1 50  TYR 50  50  50  TYR TYR A . n 
A 1 51  ALA 51  51  51  ALA ALA A . n 
A 1 52  ASP 52  52  52  ASP ASP A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  ALA 54  54  54  ALA ALA A . n 
A 1 55  SER 55  55  55  SER SER A . n 
A 1 56  ARG 56  56  56  ARG ARG A . n 
A 1 57  PHE 57  57  57  PHE PHE A . n 
A 1 58  TYR 58  58  58  TYR TYR A . n 
A 1 59  PRO 59  59  59  PRO PRO A . n 
A 1 60  HIS 60  60  60  HIS HIS A . n 
A 1 61  ALA 61  61  61  ALA ALA A . n 
A 1 62  THR 62  62  62  THR THR A . n 
A 1 63  GLY 63  63  63  GLY GLY A . n 
A 1 64  ALA 64  64  64  ALA ALA A . n 
A 1 65  ASP 65  65  65  ASP ASP A . n 
A 1 66  LEU 66  66  66  LEU LEU A . n 
A 1 67  ASP 67  67  67  ASP ASP A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  GLY 69  69  69  GLY GLY A . n 
A 1 70  VAL 70  70  70  VAL VAL A . n 
A 1 71  ASP 71  71  71  ASP ASP A . n 
A 1 72  LEU 72  72  72  LEU LEU A . n 
A 1 73  MET 73  73  73  MET MET A . n 
A 1 74  SER 74  74  74  SER SER A . n 
A 1 75  TRP 75  75  75  TRP TRP A . n 
A 1 76  ALA 76  76  76  ALA ALA A . n 
A 1 77  PHE 77  77  77  PHE PHE A . n 
A 1 78  LEU 78  78  78  LEU LEU A . n 
A 1 79  PHE 79  79  79  PHE PHE A . n 
A 1 80  ASP 80  80  80  ASP ASP A . n 
A 1 81  ASP 81  81  81  ASP ASP A . n 
A 1 82  LEU 82  82  82  LEU LEU A . n 
A 1 83  PHE 83  83  83  PHE PHE A . n 
A 1 84  ASP 84  84  84  ASP ASP A . n 
A 1 85  GLY 85  85  85  GLY GLY A . n 
A 1 86  PRO 86  86  86  PRO PRO A . n 
A 1 87  ARG 87  87  87  ARG ARG A . n 
A 1 88  GLY 88  88  88  GLY GLY A . n 
A 1 89  GLU 89  89  89  GLU GLU A . n 
A 1 90  ASN 90  90  90  ASN ASN A . n 
A 1 91  PRO 91  91  91  PRO PRO A . n 
A 1 92  GLU 92  92  92  GLU GLU A . n 
A 1 93  ASP 93  93  93  ASP ASP A . n 
A 1 94  THR 94  94  94  THR THR A . n 
A 1 95  LYS 95  95  95  LYS LYS A . n 
A 1 96  GLN 96  96  96  GLN GLN A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  THR 98  98  98  THR THR A . n 
A 1 99  ASP 99  99  99  ASP ASP A . n 
A 1 100 GLN 100 100 100 GLN GLN A . n 
A 1 101 VAL 101 101 101 VAL VAL A . n 
A 1 102 ALA 102 102 102 ALA ALA A . n 
A 1 103 ALA 103 103 103 ALA ALA A . n 
A 1 104 ALA 104 104 104 ALA ALA A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 ASP 106 106 106 ASP ASP A . n 
A 1 107 GLY 107 107 107 GLY GLY A . n 
A 1 108 PRO 108 108 108 PRO PRO A . n 
A 1 109 LEU 109 109 109 LEU LEU A . n 
A 1 110 PRO 110 110 110 PRO PRO A . n 
A 1 111 ASP 111 111 111 ASP ASP A . n 
A 1 112 THR 112 112 112 THR THR A . n 
A 1 113 ALA 113 113 113 ALA ALA A . n 
A 1 114 PRO 114 114 114 PRO PRO A . n 
A 1 115 PRO 115 115 115 PRO PRO A . n 
A 1 116 ILE 116 116 116 ILE ILE A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 HIS 118 118 118 HIS HIS A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 PHE 120 120 120 PHE PHE A . n 
A 1 121 ALA 121 121 121 ALA ALA A . n 
A 1 122 ASP 122 122 122 ASP ASP A . n 
A 1 123 ILE 123 123 123 ILE ILE A . n 
A 1 124 TRP 124 124 124 TRP TRP A . n 
A 1 125 ARG 125 125 125 ARG ARG A . n 
A 1 126 ARG 126 126 126 ARG ARG A . n 
A 1 127 THR 127 127 127 THR THR A . n 
A 1 128 CYS 128 128 128 CYS CYS A . n 
A 1 129 GLU 129 129 129 GLU GLU A . n 
A 1 130 GLY 130 130 130 GLY GLY A . n 
A 1 131 MET 131 131 131 MET MET A . n 
A 1 132 THR 132 132 132 THR THR A . n 
A 1 133 PRO 133 133 133 PRO PRO A . n 
A 1 134 ALA 134 134 134 ALA ALA A . n 
A 1 135 TRP 135 135 135 TRP TRP A . n 
A 1 136 CYS 136 136 136 CYS CYS A . n 
A 1 137 ALA 137 137 137 ALA ALA A . n 
A 1 138 ARG 138 138 138 ARG ARG A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 ARG 141 141 141 ARG ARG A . n 
A 1 142 HIS 142 142 142 HIS HIS A . n 
A 1 143 TRP 143 143 143 TRP TRP A . n 
A 1 144 ARG 144 144 144 ARG ARG A . n 
A 1 145 ASN 145 145 145 ASN ASN A . n 
A 1 146 TYR 146 146 146 TYR TYR A . n 
A 1 147 PHE 147 147 147 PHE PHE A . n 
A 1 148 ASP 148 148 148 ASP ASP A . n 
A 1 149 GLY 149 149 149 GLY GLY A . n 
A 1 150 TYR 150 150 150 TYR TYR A . n 
A 1 151 VAL 151 151 151 VAL VAL A . n 
A 1 152 ASP 152 152 152 ASP ASP A . n 
A 1 153 GLU 153 153 153 GLU GLU A . n 
A 1 154 ALA 154 154 154 ALA ALA A . n 
A 1 155 GLU 155 155 155 GLU GLU A . n 
A 1 156 SER 156 156 156 SER SER A . n 
A 1 157 ARG 157 157 157 ARG ARG A . n 
A 1 158 PHE 158 158 158 PHE PHE A . n 
A 1 159 TRP 159 159 159 TRP TRP A . n 
A 1 160 ASN 160 160 160 ASN ASN A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 PRO 162 162 162 PRO PRO A . n 
A 1 163 CYS 163 163 163 CYS CYS A . n 
A 1 164 ASP 164 164 164 ASP ASP A . n 
A 1 165 SER 165 165 165 SER SER A . n 
A 1 166 ALA 166 166 166 ALA ALA A . n 
A 1 167 ALA 167 167 167 ALA ALA A . n 
A 1 168 GLN 168 168 168 GLN GLN A . n 
A 1 169 TYR 169 169 169 TYR TYR A . n 
A 1 170 LEU 170 170 170 LEU LEU A . n 
A 1 171 ALA 171 171 171 ALA ALA A . n 
A 1 172 MET 172 172 172 MET MET A . n 
A 1 173 ARG 173 173 173 ARG ARG A . n 
A 1 174 ARG 174 174 174 ARG ARG A . n 
A 1 175 HIS 175 175 175 HIS HIS A . n 
A 1 176 THR 176 176 176 THR THR A . n 
A 1 177 ILE 177 177 177 ILE ILE A . n 
A 1 178 GLY 178 178 178 GLY GLY A . n 
A 1 179 VAL 179 179 179 VAL VAL A . n 
A 1 180 GLN 180 180 180 GLN GLN A . n 
A 1 181 PRO 181 181 181 PRO PRO A . n 
A 1 182 THR 182 182 182 THR THR A . n 
A 1 183 VAL 183 183 183 VAL VAL A . n 
A 1 184 ASP 184 184 184 ASP ASP A . n 
A 1 185 LEU 185 185 185 LEU LEU A . n 
A 1 186 ALA 186 186 186 ALA ALA A . n 
A 1 187 GLU 187 187 187 GLU GLU A . n 
A 1 188 ARG 188 188 188 ARG ARG A . n 
A 1 189 ALA 189 189 189 ALA ALA A . n 
A 1 190 GLY 190 190 190 GLY GLY A . n 
A 1 191 ARG 191 191 191 ARG ARG A . n 
A 1 192 PHE 192 192 192 PHE PHE A . n 
A 1 193 GLU 193 193 193 GLU GLU A . n 
A 1 194 VAL 194 194 194 VAL VAL A . n 
A 1 195 PRO 195 195 195 PRO PRO A . n 
A 1 196 HIS 196 196 196 HIS HIS A . n 
A 1 197 ARG 197 197 197 ARG ARG A . n 
A 1 198 VAL 198 198 198 VAL VAL A . n 
A 1 199 PHE 199 199 199 PHE PHE A . n 
A 1 200 ASP 200 200 200 ASP ASP A . n 
A 1 201 SER 201 201 201 SER SER A . n 
A 1 202 ALA 202 202 202 ALA ALA A . n 
A 1 203 VAL 203 203 203 VAL VAL A . n 
A 1 204 MET 204 204 204 MET MET A . n 
A 1 205 SER 205 205 205 SER SER A . n 
A 1 206 ALA 206 206 206 ALA ALA A . n 
A 1 207 MET 207 207 207 MET MET A . n 
A 1 208 LEU 208 208 208 LEU LEU A . n 
A 1 209 GLN 209 209 209 GLN GLN A . n 
A 1 210 ILE 210 210 210 ILE ILE A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 ASP 213 213 213 ASP ASP A . n 
A 1 214 VAL 214 214 214 VAL VAL A . n 
A 1 215 ASN 215 215 215 ASN ASN A . n 
A 1 216 LEU 216 216 216 LEU LEU A . n 
A 1 217 LEU 217 217 217 LEU LEU A . n 
A 1 218 LEU 218 218 218 LEU LEU A . n 
A 1 219 ASN 219 219 219 ASN ASN A . n 
A 1 220 ASP 220 220 220 ASP ASP A . n 
A 1 221 ILE 221 221 221 ILE ILE A . n 
A 1 222 ALA 222 222 222 ALA ALA A . n 
A 1 223 SER 223 223 223 SER SER A . n 
A 1 224 LEU 224 224 224 LEU LEU A . n 
A 1 225 GLU 225 225 225 GLU GLU A . n 
A 1 226 LYS 226 226 226 LYS LYS A . n 
A 1 227 GLU 227 227 227 GLU GLU A . n 
A 1 228 GLU 228 228 228 GLU GLU A . n 
A 1 229 ALA 229 229 229 ALA ALA A . n 
A 1 230 ARG 230 230 230 ARG ARG A . n 
A 1 231 GLY 231 231 231 GLY GLY A . n 
A 1 232 GLU 232 232 232 GLU GLU A . n 
A 1 233 GLN 233 233 233 GLN GLN A . n 
A 1 234 ASN 234 234 234 ASN ASN A . n 
A 1 235 ASN 235 235 235 ASN ASN A . n 
A 1 236 MET 236 236 236 MET MET A . n 
A 1 237 VAL 237 237 237 VAL VAL A . n 
A 1 238 MET 238 238 238 MET MET A . n 
A 1 239 ILE 239 239 239 ILE ILE A . n 
A 1 240 LEU 240 240 240 LEU LEU A . n 
A 1 241 ARG 241 241 241 ARG ARG A . n 
A 1 242 ARG 242 242 242 ARG ARG A . n 
A 1 243 GLU 243 243 243 GLU GLU A . n 
A 1 244 HIS 244 244 244 HIS HIS A . n 
A 1 245 GLY 245 245 245 GLY GLY A . n 
A 1 246 TRP 246 246 246 TRP TRP A . n 
A 1 247 SER 247 247 247 SER SER A . n 
A 1 248 LYS 248 248 248 LYS LYS A . n 
A 1 249 SER 249 249 249 SER SER A . n 
A 1 250 ARG 250 250 250 ARG ARG A . n 
A 1 251 SER 251 251 251 SER SER A . n 
A 1 252 VAL 252 252 252 VAL VAL A . n 
A 1 253 SER 253 253 253 SER SER A . n 
A 1 254 HIS 254 254 254 HIS HIS A . n 
A 1 255 MET 255 255 255 MET MET A . n 
A 1 256 GLN 256 256 256 GLN GLN A . n 
A 1 257 ASN 257 257 257 ASN ASN A . n 
A 1 258 GLU 258 258 258 GLU GLU A . n 
A 1 259 VAL 259 259 259 VAL VAL A . n 
A 1 260 ARG 260 260 260 ARG ARG A . n 
A 1 261 ALA 261 261 261 ALA ALA A . n 
A 1 262 ARG 262 262 262 ARG ARG A . n 
A 1 263 LEU 263 263 263 LEU LEU A . n 
A 1 264 GLU 264 264 264 GLU GLU A . n 
A 1 265 GLN 265 265 265 GLN GLN A . n 
A 1 266 TYR 266 266 266 TYR TYR A . n 
A 1 267 LEU 267 267 267 LEU LEU A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 LEU 269 269 269 LEU LEU A . n 
A 1 270 GLU 270 270 270 GLU GLU A . n 
A 1 271 SER 271 271 271 SER SER A . n 
A 1 272 CYS 272 272 272 CYS CYS A . n 
A 1 273 LEU 273 273 273 LEU LEU A . n 
A 1 274 PRO 274 274 274 PRO PRO A . n 
A 1 275 LYS 275 275 275 LYS LYS A . n 
A 1 276 VAL 276 276 276 VAL VAL A . n 
A 1 277 GLY 277 277 277 GLY GLY A . n 
A 1 278 GLU 278 278 278 GLU GLU A . n 
A 1 279 ILE 279 279 279 ILE ILE A . n 
A 1 280 TYR 280 280 280 TYR TYR A . n 
A 1 281 GLN 281 281 281 GLN GLN A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 ASP 283 283 283 ASP ASP A . n 
A 1 284 THR 284 284 284 THR THR A . n 
A 1 285 ALA 285 285 285 ALA ALA A . n 
A 1 286 GLU 286 286 286 GLU GLU A . n 
A 1 287 ARG 287 287 287 ARG ARG A . n 
A 1 288 GLU 288 288 288 GLU GLU A . n 
A 1 289 ALA 289 289 289 ALA ALA A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 GLU 291 291 291 GLU GLU A . n 
A 1 292 ARG 292 292 292 ARG ARG A . n 
A 1 293 TYR 293 293 293 TYR TYR A . n 
A 1 294 ARG 294 294 294 ARG ARG A . n 
A 1 295 THR 295 295 295 THR THR A . n 
A 1 296 ASP 296 296 296 ASP ASP A . n 
A 1 297 ALA 297 297 297 ALA ALA A . n 
A 1 298 VAL 298 298 298 VAL VAL A . n 
A 1 299 ARG 299 299 299 ARG ARG A . n 
A 1 300 THR 300 300 300 THR THR A . n 
A 1 301 VAL 301 301 301 VAL VAL A . n 
A 1 302 ILE 302 302 302 ILE ILE A . n 
A 1 303 ARG 303 303 303 ARG ARG A . n 
A 1 304 GLY 304 304 304 GLY GLY A . n 
A 1 305 SER 305 305 305 SER SER A . n 
A 1 306 TYR 306 306 306 TYR TYR A . n 
A 1 307 ASP 307 307 307 ASP ASP A . n 
A 1 308 TRP 308 308 308 TRP TRP A . n 
A 1 309 HIS 309 309 309 HIS HIS A . n 
A 1 310 ARG 310 310 310 ARG ARG A . n 
A 1 311 SER 311 311 311 SER SER A . n 
A 1 312 SER 312 312 312 SER SER A . n 
A 1 313 GLY 313 313 313 GLY GLY A . n 
A 1 314 ARG 314 314 314 ARG ARG A . n 
A 1 315 TYR 315 315 315 TYR TYR A . n 
A 1 316 ASP 316 316 316 ASP ASP A . n 
A 1 317 ALA 317 317 ?   ?   ?   A . n 
A 1 318 GLU 318 318 ?   ?   ?   A . n 
A 1 319 PHE 319 319 ?   ?   ?   A . n 
A 1 320 ALA 320 320 ?   ?   ?   A . n 
A 1 321 LEU 321 321 ?   ?   ?   A . n 
A 1 322 ALA 322 322 ?   ?   ?   A . n 
A 1 323 ALA 323 323 ?   ?   ?   A . n 
A 1 324 GLY 324 324 ?   ?   ?   A . n 
A 1 325 ALA 325 325 325 ALA ALA A . n 
A 1 326 GLN 326 326 326 GLN GLN A . n 
A 1 327 GLY 327 327 327 GLY GLY A . n 
A 1 328 TYR 328 328 328 TYR TYR A . n 
A 1 329 LEU 329 329 329 LEU LEU A . n 
A 1 330 GLU 330 330 330 GLU GLU A . n 
A 1 331 GLU 331 331 331 GLU GLU A . n 
A 1 332 LEU 332 332 332 LEU LEU A . n 
A 1 333 GLY 333 333 333 GLY GLY A . n 
A 1 334 SER 334 334 334 SER SER A . n 
A 1 335 SER 335 335 335 SER SER A . n 
A 1 336 ALA 336 336 ?   ?   ?   A . n 
A 1 337 HIS 337 337 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   PRO 2   2   ?   ?   ?   B . n 
B 1 3   GLN 3   3   ?   ?   ?   B . n 
B 1 4   ASP 4   4   ?   ?   ?   B . n 
B 1 5   VAL 5   5   5   VAL VAL B . n 
B 1 6   ASP 6   6   6   ASP ASP B . n 
B 1 7   PHE 7   7   7   PHE PHE B . n 
B 1 8   HIS 8   8   8   HIS HIS B . n 
B 1 9   ILE 9   9   9   ILE ILE B . n 
B 1 10  PRO 10  10  10  PRO PRO B . n 
B 1 11  LEU 11  11  11  LEU LEU B . n 
B 1 12  PRO 12  12  12  PRO PRO B . n 
B 1 13  GLY 13  13  13  GLY GLY B . n 
B 1 14  ARG 14  14  14  ARG ARG B . n 
B 1 15  GLN 15  15  15  GLN GLN B . n 
B 1 16  SER 16  16  16  SER SER B . n 
B 1 17  PRO 17  17  17  PRO PRO B . n 
B 1 18  ASP 18  18  18  ASP ASP B . n 
B 1 19  HIS 19  19  19  HIS HIS B . n 
B 1 20  ALA 20  20  20  ALA ALA B . n 
B 1 21  ARG 21  21  21  ARG ARG B . n 
B 1 22  ALA 22  22  22  ALA ALA B . n 
B 1 23  GLU 23  23  23  GLU GLU B . n 
B 1 24  ALA 24  24  24  ALA ALA B . n 
B 1 25  GLU 25  25  25  GLU GLU B . n 
B 1 26  GLN 26  26  26  GLN GLN B . n 
B 1 27  LEU 27  27  27  LEU LEU B . n 
B 1 28  ALA 28  28  28  ALA ALA B . n 
B 1 29  TRP 29  29  29  TRP TRP B . n 
B 1 30  PRO 30  30  30  PRO PRO B . n 
B 1 31  ARG 31  31  31  ARG ARG B . n 
B 1 32  SER 32  32  32  SER SER B . n 
B 1 33  LEU 33  33  33  LEU LEU B . n 
B 1 34  GLY 34  34  34  GLY GLY B . n 
B 1 35  LEU 35  35  35  LEU LEU B . n 
B 1 36  ILE 36  36  36  ILE ILE B . n 
B 1 37  ARG 37  37  37  ARG ARG B . n 
B 1 38  SER 38  38  38  SER SER B . n 
B 1 39  ASP 39  39  39  ASP ASP B . n 
B 1 40  ALA 40  40  40  ALA ALA B . n 
B 1 41  ALA 41  41  41  ALA ALA B . n 
B 1 42  ALA 42  42  42  ALA ALA B . n 
B 1 43  GLU 43  43  43  GLU GLU B . n 
B 1 44  ARG 44  44  44  ARG ARG B . n 
B 1 45  HIS 45  45  45  HIS HIS B . n 
B 1 46  LEU 46  46  46  LEU LEU B . n 
B 1 47  ARG 47  47  47  ARG ARG B . n 
B 1 48  GLY 48  48  48  GLY GLY B . n 
B 1 49  GLY 49  49  49  GLY GLY B . n 
B 1 50  TYR 50  50  50  TYR TYR B . n 
B 1 51  ALA 51  51  51  ALA ALA B . n 
B 1 52  ASP 52  52  52  ASP ASP B . n 
B 1 53  LEU 53  53  53  LEU LEU B . n 
B 1 54  ALA 54  54  54  ALA ALA B . n 
B 1 55  SER 55  55  55  SER SER B . n 
B 1 56  ARG 56  56  56  ARG ARG B . n 
B 1 57  PHE 57  57  57  PHE PHE B . n 
B 1 58  TYR 58  58  58  TYR TYR B . n 
B 1 59  PRO 59  59  59  PRO PRO B . n 
B 1 60  HIS 60  60  60  HIS HIS B . n 
B 1 61  ALA 61  61  61  ALA ALA B . n 
B 1 62  THR 62  62  62  THR THR B . n 
B 1 63  GLY 63  63  63  GLY GLY B . n 
B 1 64  ALA 64  64  64  ALA ALA B . n 
B 1 65  ASP 65  65  65  ASP ASP B . n 
B 1 66  LEU 66  66  66  LEU LEU B . n 
B 1 67  ASP 67  67  67  ASP ASP B . n 
B 1 68  LEU 68  68  68  LEU LEU B . n 
B 1 69  GLY 69  69  69  GLY GLY B . n 
B 1 70  VAL 70  70  70  VAL VAL B . n 
B 1 71  ASP 71  71  71  ASP ASP B . n 
B 1 72  LEU 72  72  72  LEU LEU B . n 
B 1 73  MET 73  73  73  MET MET B . n 
B 1 74  SER 74  74  74  SER SER B . n 
B 1 75  TRP 75  75  75  TRP TRP B . n 
B 1 76  ALA 76  76  76  ALA ALA B . n 
B 1 77  PHE 77  77  77  PHE PHE B . n 
B 1 78  LEU 78  78  78  LEU LEU B . n 
B 1 79  PHE 79  79  79  PHE PHE B . n 
B 1 80  ASP 80  80  80  ASP ASP B . n 
B 1 81  ASP 81  81  81  ASP ASP B . n 
B 1 82  LEU 82  82  82  LEU LEU B . n 
B 1 83  PHE 83  83  83  PHE PHE B . n 
B 1 84  ASP 84  84  84  ASP ASP B . n 
B 1 85  GLY 85  85  85  GLY GLY B . n 
B 1 86  PRO 86  86  86  PRO PRO B . n 
B 1 87  ARG 87  87  87  ARG ARG B . n 
B 1 88  GLY 88  88  88  GLY GLY B . n 
B 1 89  GLU 89  89  89  GLU GLU B . n 
B 1 90  ASN 90  90  90  ASN ASN B . n 
B 1 91  PRO 91  91  91  PRO PRO B . n 
B 1 92  GLU 92  92  92  GLU GLU B . n 
B 1 93  ASP 93  93  93  ASP ASP B . n 
B 1 94  THR 94  94  94  THR THR B . n 
B 1 95  LYS 95  95  95  LYS LYS B . n 
B 1 96  GLN 96  96  96  GLN GLN B . n 
B 1 97  LEU 97  97  97  LEU LEU B . n 
B 1 98  THR 98  98  98  THR THR B . n 
B 1 99  ASP 99  99  99  ASP ASP B . n 
B 1 100 GLN 100 100 100 GLN GLN B . n 
B 1 101 VAL 101 101 101 VAL VAL B . n 
B 1 102 ALA 102 102 102 ALA ALA B . n 
B 1 103 ALA 103 103 103 ALA ALA B . n 
B 1 104 ALA 104 104 104 ALA ALA B . n 
B 1 105 LEU 105 105 105 LEU LEU B . n 
B 1 106 ASP 106 106 106 ASP ASP B . n 
B 1 107 GLY 107 107 107 GLY GLY B . n 
B 1 108 PRO 108 108 108 PRO PRO B . n 
B 1 109 LEU 109 109 109 LEU LEU B . n 
B 1 110 PRO 110 110 110 PRO PRO B . n 
B 1 111 ASP 111 111 111 ASP ASP B . n 
B 1 112 THR 112 112 112 THR THR B . n 
B 1 113 ALA 113 113 113 ALA ALA B . n 
B 1 114 PRO 114 114 114 PRO PRO B . n 
B 1 115 PRO 115 115 115 PRO PRO B . n 
B 1 116 ILE 116 116 116 ILE ILE B . n 
B 1 117 ALA 117 117 117 ALA ALA B . n 
B 1 118 HIS 118 118 118 HIS HIS B . n 
B 1 119 GLY 119 119 119 GLY GLY B . n 
B 1 120 PHE 120 120 120 PHE PHE B . n 
B 1 121 ALA 121 121 121 ALA ALA B . n 
B 1 122 ASP 122 122 122 ASP ASP B . n 
B 1 123 ILE 123 123 123 ILE ILE B . n 
B 1 124 TRP 124 124 124 TRP TRP B . n 
B 1 125 ARG 125 125 125 ARG ARG B . n 
B 1 126 ARG 126 126 126 ARG ARG B . n 
B 1 127 THR 127 127 127 THR THR B . n 
B 1 128 CYS 128 128 128 CYS CYS B . n 
B 1 129 GLU 129 129 129 GLU GLU B . n 
B 1 130 GLY 130 130 130 GLY GLY B . n 
B 1 131 MET 131 131 131 MET MET B . n 
B 1 132 THR 132 132 132 THR THR B . n 
B 1 133 PRO 133 133 133 PRO PRO B . n 
B 1 134 ALA 134 134 134 ALA ALA B . n 
B 1 135 TRP 135 135 135 TRP TRP B . n 
B 1 136 CYS 136 136 136 CYS CYS B . n 
B 1 137 ALA 137 137 137 ALA ALA B . n 
B 1 138 ARG 138 138 138 ARG ARG B . n 
B 1 139 SER 139 139 139 SER SER B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 ARG 141 141 141 ARG ARG B . n 
B 1 142 HIS 142 142 142 HIS HIS B . n 
B 1 143 TRP 143 143 143 TRP TRP B . n 
B 1 144 ARG 144 144 144 ARG ARG B . n 
B 1 145 ASN 145 145 145 ASN ASN B . n 
B 1 146 TYR 146 146 146 TYR TYR B . n 
B 1 147 PHE 147 147 147 PHE PHE B . n 
B 1 148 ASP 148 148 148 ASP ASP B . n 
B 1 149 GLY 149 149 149 GLY GLY B . n 
B 1 150 TYR 150 150 150 TYR TYR B . n 
B 1 151 VAL 151 151 151 VAL VAL B . n 
B 1 152 ASP 152 152 152 ASP ASP B . n 
B 1 153 GLU 153 153 153 GLU GLU B . n 
B 1 154 ALA 154 154 154 ALA ALA B . n 
B 1 155 GLU 155 155 155 GLU GLU B . n 
B 1 156 SER 156 156 156 SER SER B . n 
B 1 157 ARG 157 157 157 ARG ARG B . n 
B 1 158 PHE 158 158 158 PHE PHE B . n 
B 1 159 TRP 159 159 159 TRP TRP B . n 
B 1 160 ASN 160 160 160 ASN ASN B . n 
B 1 161 ALA 161 161 161 ALA ALA B . n 
B 1 162 PRO 162 162 162 PRO PRO B . n 
B 1 163 CYS 163 163 163 CYS CYS B . n 
B 1 164 ASP 164 164 164 ASP ASP B . n 
B 1 165 SER 165 165 165 SER SER B . n 
B 1 166 ALA 166 166 166 ALA ALA B . n 
B 1 167 ALA 167 167 167 ALA ALA B . n 
B 1 168 GLN 168 168 168 GLN GLN B . n 
B 1 169 TYR 169 169 169 TYR TYR B . n 
B 1 170 LEU 170 170 170 LEU LEU B . n 
B 1 171 ALA 171 171 171 ALA ALA B . n 
B 1 172 MET 172 172 172 MET MET B . n 
B 1 173 ARG 173 173 173 ARG ARG B . n 
B 1 174 ARG 174 174 174 ARG ARG B . n 
B 1 175 HIS 175 175 175 HIS HIS B . n 
B 1 176 THR 176 176 176 THR THR B . n 
B 1 177 ILE 177 177 177 ILE ILE B . n 
B 1 178 GLY 178 178 178 GLY GLY B . n 
B 1 179 VAL 179 179 179 VAL VAL B . n 
B 1 180 GLN 180 180 180 GLN GLN B . n 
B 1 181 PRO 181 181 181 PRO PRO B . n 
B 1 182 THR 182 182 182 THR THR B . n 
B 1 183 VAL 183 183 183 VAL VAL B . n 
B 1 184 ASP 184 184 184 ASP ASP B . n 
B 1 185 LEU 185 185 185 LEU LEU B . n 
B 1 186 ALA 186 186 186 ALA ALA B . n 
B 1 187 GLU 187 187 187 GLU GLU B . n 
B 1 188 ARG 188 188 188 ARG ARG B . n 
B 1 189 ALA 189 189 189 ALA ALA B . n 
B 1 190 GLY 190 190 190 GLY GLY B . n 
B 1 191 ARG 191 191 191 ARG ARG B . n 
B 1 192 PHE 192 192 192 PHE PHE B . n 
B 1 193 GLU 193 193 193 GLU GLU B . n 
B 1 194 VAL 194 194 194 VAL VAL B . n 
B 1 195 PRO 195 195 195 PRO PRO B . n 
B 1 196 HIS 196 196 196 HIS HIS B . n 
B 1 197 ARG 197 197 197 ARG ARG B . n 
B 1 198 VAL 198 198 198 VAL VAL B . n 
B 1 199 PHE 199 199 199 PHE PHE B . n 
B 1 200 ASP 200 200 200 ASP ASP B . n 
B 1 201 SER 201 201 201 SER SER B . n 
B 1 202 ALA 202 202 202 ALA ALA B . n 
B 1 203 VAL 203 203 203 VAL VAL B . n 
B 1 204 MET 204 204 204 MET MET B . n 
B 1 205 SER 205 205 205 SER SER B . n 
B 1 206 ALA 206 206 206 ALA ALA B . n 
B 1 207 MET 207 207 207 MET MET B . n 
B 1 208 LEU 208 208 208 LEU LEU B . n 
B 1 209 GLN 209 209 209 GLN GLN B . n 
B 1 210 ILE 210 210 210 ILE ILE B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 VAL 212 212 212 VAL VAL B . n 
B 1 213 ASP 213 213 213 ASP ASP B . n 
B 1 214 VAL 214 214 214 VAL VAL B . n 
B 1 215 ASN 215 215 215 ASN ASN B . n 
B 1 216 LEU 216 216 216 LEU LEU B . n 
B 1 217 LEU 217 217 217 LEU LEU B . n 
B 1 218 LEU 218 218 218 LEU LEU B . n 
B 1 219 ASN 219 219 219 ASN ASN B . n 
B 1 220 ASP 220 220 220 ASP ASP B . n 
B 1 221 ILE 221 221 221 ILE ILE B . n 
B 1 222 ALA 222 222 222 ALA ALA B . n 
B 1 223 SER 223 223 223 SER SER B . n 
B 1 224 LEU 224 224 224 LEU LEU B . n 
B 1 225 GLU 225 225 225 GLU GLU B . n 
B 1 226 LYS 226 226 226 LYS LYS B . n 
B 1 227 GLU 227 227 227 GLU GLU B . n 
B 1 228 GLU 228 228 228 GLU GLU B . n 
B 1 229 ALA 229 229 229 ALA ALA B . n 
B 1 230 ARG 230 230 230 ARG ARG B . n 
B 1 231 GLY 231 231 231 GLY GLY B . n 
B 1 232 GLU 232 232 232 GLU GLU B . n 
B 1 233 GLN 233 233 233 GLN GLN B . n 
B 1 234 ASN 234 234 234 ASN ASN B . n 
B 1 235 ASN 235 235 235 ASN ASN B . n 
B 1 236 MET 236 236 236 MET MET B . n 
B 1 237 VAL 237 237 237 VAL VAL B . n 
B 1 238 MET 238 238 238 MET MET B . n 
B 1 239 ILE 239 239 239 ILE ILE B . n 
B 1 240 LEU 240 240 240 LEU LEU B . n 
B 1 241 ARG 241 241 241 ARG ARG B . n 
B 1 242 ARG 242 242 242 ARG ARG B . n 
B 1 243 GLU 243 243 243 GLU GLU B . n 
B 1 244 HIS 244 244 244 HIS HIS B . n 
B 1 245 GLY 245 245 245 GLY GLY B . n 
B 1 246 TRP 246 246 246 TRP TRP B . n 
B 1 247 SER 247 247 247 SER SER B . n 
B 1 248 LYS 248 248 248 LYS LYS B . n 
B 1 249 SER 249 249 249 SER SER B . n 
B 1 250 ARG 250 250 250 ARG ARG B . n 
B 1 251 SER 251 251 251 SER SER B . n 
B 1 252 VAL 252 252 252 VAL VAL B . n 
B 1 253 SER 253 253 253 SER SER B . n 
B 1 254 HIS 254 254 254 HIS HIS B . n 
B 1 255 MET 255 255 255 MET MET B . n 
B 1 256 GLN 256 256 256 GLN GLN B . n 
B 1 257 ASN 257 257 257 ASN ASN B . n 
B 1 258 GLU 258 258 258 GLU GLU B . n 
B 1 259 VAL 259 259 259 VAL VAL B . n 
B 1 260 ARG 260 260 260 ARG ARG B . n 
B 1 261 ALA 261 261 261 ALA ALA B . n 
B 1 262 ARG 262 262 262 ARG ARG B . n 
B 1 263 LEU 263 263 263 LEU LEU B . n 
B 1 264 GLU 264 264 264 GLU GLU B . n 
B 1 265 GLN 265 265 265 GLN GLN B . n 
B 1 266 TYR 266 266 266 TYR TYR B . n 
B 1 267 LEU 267 267 267 LEU LEU B . n 
B 1 268 LEU 268 268 268 LEU LEU B . n 
B 1 269 LEU 269 269 269 LEU LEU B . n 
B 1 270 GLU 270 270 270 GLU GLU B . n 
B 1 271 SER 271 271 271 SER SER B . n 
B 1 272 CYS 272 272 272 CYS CYS B . n 
B 1 273 LEU 273 273 273 LEU LEU B . n 
B 1 274 PRO 274 274 274 PRO PRO B . n 
B 1 275 LYS 275 275 275 LYS LYS B . n 
B 1 276 VAL 276 276 276 VAL VAL B . n 
B 1 277 GLY 277 277 277 GLY GLY B . n 
B 1 278 GLU 278 278 278 GLU GLU B . n 
B 1 279 ILE 279 279 279 ILE ILE B . n 
B 1 280 TYR 280 280 280 TYR TYR B . n 
B 1 281 GLN 281 281 281 GLN GLN B . n 
B 1 282 LEU 282 282 282 LEU LEU B . n 
B 1 283 ASP 283 283 283 ASP ASP B . n 
B 1 284 THR 284 284 284 THR THR B . n 
B 1 285 ALA 285 285 285 ALA ALA B . n 
B 1 286 GLU 286 286 286 GLU GLU B . n 
B 1 287 ARG 287 287 287 ARG ARG B . n 
B 1 288 GLU 288 288 288 GLU GLU B . n 
B 1 289 ALA 289 289 289 ALA ALA B . n 
B 1 290 LEU 290 290 290 LEU LEU B . n 
B 1 291 GLU 291 291 291 GLU GLU B . n 
B 1 292 ARG 292 292 292 ARG ARG B . n 
B 1 293 TYR 293 293 293 TYR TYR B . n 
B 1 294 ARG 294 294 294 ARG ARG B . n 
B 1 295 THR 295 295 295 THR THR B . n 
B 1 296 ASP 296 296 296 ASP ASP B . n 
B 1 297 ALA 297 297 297 ALA ALA B . n 
B 1 298 VAL 298 298 298 VAL VAL B . n 
B 1 299 ARG 299 299 299 ARG ARG B . n 
B 1 300 THR 300 300 300 THR THR B . n 
B 1 301 VAL 301 301 301 VAL VAL B . n 
B 1 302 ILE 302 302 302 ILE ILE B . n 
B 1 303 ARG 303 303 303 ARG ARG B . n 
B 1 304 GLY 304 304 304 GLY GLY B . n 
B 1 305 SER 305 305 305 SER SER B . n 
B 1 306 TYR 306 306 306 TYR TYR B . n 
B 1 307 ASP 307 307 307 ASP ASP B . n 
B 1 308 TRP 308 308 308 TRP TRP B . n 
B 1 309 HIS 309 309 309 HIS HIS B . n 
B 1 310 ARG 310 310 310 ARG ARG B . n 
B 1 311 SER 311 311 311 SER SER B . n 
B 1 312 SER 312 312 ?   ?   ?   B . n 
B 1 313 GLY 313 313 ?   ?   ?   B . n 
B 1 314 ARG 314 314 ?   ?   ?   B . n 
B 1 315 TYR 315 315 ?   ?   ?   B . n 
B 1 316 ASP 316 316 ?   ?   ?   B . n 
B 1 317 ALA 317 317 ?   ?   ?   B . n 
B 1 318 GLU 318 318 ?   ?   ?   B . n 
B 1 319 PHE 319 319 ?   ?   ?   B . n 
B 1 320 ALA 320 320 ?   ?   ?   B . n 
B 1 321 LEU 321 321 ?   ?   ?   B . n 
B 1 322 ALA 322 322 ?   ?   ?   B . n 
B 1 323 ALA 323 323 ?   ?   ?   B . n 
B 1 324 GLY 324 324 ?   ?   ?   B . n 
B 1 325 ALA 325 325 ?   ?   ?   B . n 
B 1 326 GLN 326 326 ?   ?   ?   B . n 
B 1 327 GLY 327 327 ?   ?   ?   B . n 
B 1 328 TYR 328 328 ?   ?   ?   B . n 
B 1 329 LEU 329 329 ?   ?   ?   B . n 
B 1 330 GLU 330 330 ?   ?   ?   B . n 
B 1 331 GLU 331 331 ?   ?   ?   B . n 
B 1 332 LEU 332 332 ?   ?   ?   B . n 
B 1 333 GLY 333 333 ?   ?   ?   B . n 
B 1 334 SER 334 334 ?   ?   ?   B . n 
B 1 335 SER 335 335 ?   ?   ?   B . n 
B 1 336 ALA 336 336 ?   ?   ?   B . n 
B 1 337 HIS 337 337 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        FPF 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   FPF 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 FPF 1   401 401 FPF FPF A . 
D 3 MG  1   402 1   MG  MG  A . 
E 3 MG  1   403 2   MG  MG  A . 
F 3 MG  1   404 3   MG  MG  A . 
G 4 HOH 1   501 221 HOH HOH A . 
G 4 HOH 2   502 275 HOH HOH A . 
G 4 HOH 3   503 296 HOH HOH A . 
G 4 HOH 4   504 261 HOH HOH A . 
G 4 HOH 5   505 262 HOH HOH A . 
G 4 HOH 6   506 247 HOH HOH A . 
G 4 HOH 7   507 233 HOH HOH A . 
G 4 HOH 8   508 279 HOH HOH A . 
G 4 HOH 9   509 278 HOH HOH A . 
G 4 HOH 10  510 64  HOH HOH A . 
G 4 HOH 11  511 232 HOH HOH A . 
G 4 HOH 12  512 165 HOH HOH A . 
G 4 HOH 13  513 25  HOH HOH A . 
G 4 HOH 14  514 230 HOH HOH A . 
G 4 HOH 15  515 41  HOH HOH A . 
G 4 HOH 16  516 179 HOH HOH A . 
G 4 HOH 17  517 57  HOH HOH A . 
G 4 HOH 18  518 209 HOH HOH A . 
G 4 HOH 19  519 2   HOH HOH A . 
G 4 HOH 20  520 171 HOH HOH A . 
G 4 HOH 21  521 28  HOH HOH A . 
G 4 HOH 22  522 70  HOH HOH A . 
G 4 HOH 23  523 285 HOH HOH A . 
G 4 HOH 24  524 90  HOH HOH A . 
G 4 HOH 25  525 48  HOH HOH A . 
G 4 HOH 26  526 144 HOH HOH A . 
G 4 HOH 27  527 4   HOH HOH A . 
G 4 HOH 28  528 74  HOH HOH A . 
G 4 HOH 29  529 129 HOH HOH A . 
G 4 HOH 30  530 69  HOH HOH A . 
G 4 HOH 31  531 97  HOH HOH A . 
G 4 HOH 32  532 20  HOH HOH A . 
G 4 HOH 33  533 76  HOH HOH A . 
G 4 HOH 34  534 260 HOH HOH A . 
G 4 HOH 35  535 24  HOH HOH A . 
G 4 HOH 36  536 16  HOH HOH A . 
G 4 HOH 37  537 42  HOH HOH A . 
G 4 HOH 38  538 255 HOH HOH A . 
G 4 HOH 39  539 243 HOH HOH A . 
G 4 HOH 40  540 297 HOH HOH A . 
G 4 HOH 41  541 13  HOH HOH A . 
G 4 HOH 42  542 26  HOH HOH A . 
G 4 HOH 43  543 18  HOH HOH A . 
G 4 HOH 44  544 62  HOH HOH A . 
G 4 HOH 45  545 49  HOH HOH A . 
G 4 HOH 46  546 281 HOH HOH A . 
G 4 HOH 47  547 256 HOH HOH A . 
G 4 HOH 48  548 45  HOH HOH A . 
G 4 HOH 49  549 79  HOH HOH A . 
G 4 HOH 50  550 1   HOH HOH A . 
G 4 HOH 51  551 290 HOH HOH A . 
G 4 HOH 52  552 10  HOH HOH A . 
G 4 HOH 53  553 35  HOH HOH A . 
G 4 HOH 54  554 215 HOH HOH A . 
G 4 HOH 55  555 80  HOH HOH A . 
G 4 HOH 56  556 126 HOH HOH A . 
G 4 HOH 57  557 182 HOH HOH A . 
G 4 HOH 58  558 3   HOH HOH A . 
G 4 HOH 59  559 159 HOH HOH A . 
G 4 HOH 60  560 111 HOH HOH A . 
G 4 HOH 61  561 52  HOH HOH A . 
G 4 HOH 62  562 53  HOH HOH A . 
G 4 HOH 63  563 14  HOH HOH A . 
G 4 HOH 64  564 164 HOH HOH A . 
G 4 HOH 65  565 289 HOH HOH A . 
G 4 HOH 66  566 34  HOH HOH A . 
G 4 HOH 67  567 272 HOH HOH A . 
G 4 HOH 68  568 12  HOH HOH A . 
G 4 HOH 69  569 175 HOH HOH A . 
G 4 HOH 70  570 29  HOH HOH A . 
G 4 HOH 71  571 72  HOH HOH A . 
G 4 HOH 72  572 254 HOH HOH A . 
G 4 HOH 73  573 128 HOH HOH A . 
G 4 HOH 74  574 287 HOH HOH A . 
G 4 HOH 75  575 106 HOH HOH A . 
G 4 HOH 76  576 201 HOH HOH A . 
G 4 HOH 77  577 7   HOH HOH A . 
G 4 HOH 78  578 183 HOH HOH A . 
G 4 HOH 79  579 38  HOH HOH A . 
G 4 HOH 80  580 19  HOH HOH A . 
G 4 HOH 81  581 17  HOH HOH A . 
G 4 HOH 82  582 87  HOH HOH A . 
G 4 HOH 83  583 196 HOH HOH A . 
G 4 HOH 84  584 299 HOH HOH A . 
G 4 HOH 85  585 160 HOH HOH A . 
G 4 HOH 86  586 66  HOH HOH A . 
G 4 HOH 87  587 71  HOH HOH A . 
G 4 HOH 88  588 240 HOH HOH A . 
G 4 HOH 89  589 204 HOH HOH A . 
G 4 HOH 90  590 67  HOH HOH A . 
G 4 HOH 91  591 292 HOH HOH A . 
G 4 HOH 92  592 93  HOH HOH A . 
G 4 HOH 93  593 345 HOH HOH A . 
G 4 HOH 94  594 107 HOH HOH A . 
G 4 HOH 95  595 91  HOH HOH A . 
G 4 HOH 96  596 84  HOH HOH A . 
G 4 HOH 97  597 148 HOH HOH A . 
G 4 HOH 98  598 92  HOH HOH A . 
G 4 HOH 99  599 36  HOH HOH A . 
G 4 HOH 100 600 257 HOH HOH A . 
G 4 HOH 101 601 86  HOH HOH A . 
G 4 HOH 102 602 271 HOH HOH A . 
G 4 HOH 103 603 282 HOH HOH A . 
G 4 HOH 104 604 47  HOH HOH A . 
G 4 HOH 105 605 218 HOH HOH A . 
G 4 HOH 106 606 177 HOH HOH A . 
G 4 HOH 107 607 115 HOH HOH A . 
G 4 HOH 108 608 286 HOH HOH A . 
G 4 HOH 109 609 300 HOH HOH A . 
G 4 HOH 110 610 77  HOH HOH A . 
G 4 HOH 111 611 112 HOH HOH A . 
G 4 HOH 112 612 288 HOH HOH A . 
G 4 HOH 113 613 265 HOH HOH A . 
G 4 HOH 114 614 244 HOH HOH A . 
G 4 HOH 115 615 294 HOH HOH A . 
G 4 HOH 116 616 40  HOH HOH A . 
G 4 HOH 117 617 15  HOH HOH A . 
G 4 HOH 118 618 213 HOH HOH A . 
G 4 HOH 119 619 280 HOH HOH A . 
G 4 HOH 120 620 283 HOH HOH A . 
G 4 HOH 121 621 146 HOH HOH A . 
G 4 HOH 122 622 188 HOH HOH A . 
G 4 HOH 123 623 95  HOH HOH A . 
G 4 HOH 124 624 22  HOH HOH A . 
G 4 HOH 125 625 184 HOH HOH A . 
G 4 HOH 126 626 31  HOH HOH A . 
G 4 HOH 127 627 118 HOH HOH A . 
G 4 HOH 128 628 303 HOH HOH A . 
G 4 HOH 129 629 78  HOH HOH A . 
G 4 HOH 130 630 125 HOH HOH A . 
G 4 HOH 131 631 249 HOH HOH A . 
G 4 HOH 132 632 291 HOH HOH A . 
G 4 HOH 133 633 207 HOH HOH A . 
G 4 HOH 134 634 269 HOH HOH A . 
G 4 HOH 135 635 51  HOH HOH A . 
G 4 HOH 136 636 259 HOH HOH A . 
G 4 HOH 137 637 284 HOH HOH A . 
G 4 HOH 138 638 105 HOH HOH A . 
G 4 HOH 139 639 180 HOH HOH A . 
G 4 HOH 140 640 59  HOH HOH A . 
G 4 HOH 141 641 298 HOH HOH A . 
G 4 HOH 142 642 253 HOH HOH A . 
G 4 HOH 143 643 274 HOH HOH A . 
G 4 HOH 144 644 155 HOH HOH A . 
G 4 HOH 145 645 147 HOH HOH A . 
G 4 HOH 146 646 277 HOH HOH A . 
G 4 HOH 147 647 168 HOH HOH A . 
G 4 HOH 148 648 208 HOH HOH A . 
G 4 HOH 149 649 268 HOH HOH A . 
G 4 HOH 150 650 241 HOH HOH A . 
G 4 HOH 151 651 185 HOH HOH A . 
G 4 HOH 152 652 88  HOH HOH A . 
G 4 HOH 153 653 137 HOH HOH A . 
G 4 HOH 154 654 226 HOH HOH A . 
G 4 HOH 155 655 120 HOH HOH A . 
G 4 HOH 156 656 172 HOH HOH A . 
G 4 HOH 157 657 258 HOH HOH A . 
G 4 HOH 158 658 273 HOH HOH A . 
G 4 HOH 159 659 224 HOH HOH A . 
G 4 HOH 160 660 267 HOH HOH A . 
G 4 HOH 161 661 339 HOH HOH A . 
G 4 HOH 162 662 252 HOH HOH A . 
G 4 HOH 163 663 162 HOH HOH A . 
G 4 HOH 164 664 202 HOH HOH A . 
G 4 HOH 165 665 270 HOH HOH A . 
G 4 HOH 166 666 167 HOH HOH A . 
G 4 HOH 167 667 96  HOH HOH A . 
G 4 HOH 168 668 276 HOH HOH A . 
G 4 HOH 169 669 295 HOH HOH A . 
G 4 HOH 170 670 139 HOH HOH A . 
G 4 HOH 171 671 331 HOH HOH A . 
G 4 HOH 172 672 293 HOH HOH A . 
G 4 HOH 173 673 186 HOH HOH A . 
G 4 HOH 174 674 149 HOH HOH A . 
G 4 HOH 175 675 212 HOH HOH A . 
G 4 HOH 176 676 337 HOH HOH A . 
H 4 HOH 1   401 320 HOH HOH B . 
H 4 HOH 2   402 163 HOH HOH B . 
H 4 HOH 3   403 124 HOH HOH B . 
H 4 HOH 4   404 55  HOH HOH B . 
H 4 HOH 5   405 322 HOH HOH B . 
H 4 HOH 6   406 307 HOH HOH B . 
H 4 HOH 7   407 56  HOH HOH B . 
H 4 HOH 8   408 54  HOH HOH B . 
H 4 HOH 9   409 133 HOH HOH B . 
H 4 HOH 10  410 58  HOH HOH B . 
H 4 HOH 11  411 210 HOH HOH B . 
H 4 HOH 12  412 65  HOH HOH B . 
H 4 HOH 13  413 108 HOH HOH B . 
H 4 HOH 14  414 73  HOH HOH B . 
H 4 HOH 15  415 8   HOH HOH B . 
H 4 HOH 16  416 194 HOH HOH B . 
H 4 HOH 17  417 316 HOH HOH B . 
H 4 HOH 18  418 101 HOH HOH B . 
H 4 HOH 19  419 333 HOH HOH B . 
H 4 HOH 20  420 197 HOH HOH B . 
H 4 HOH 21  421 122 HOH HOH B . 
H 4 HOH 22  422 178 HOH HOH B . 
H 4 HOH 23  423 325 HOH HOH B . 
H 4 HOH 24  424 132 HOH HOH B . 
H 4 HOH 25  425 100 HOH HOH B . 
H 4 HOH 26  426 109 HOH HOH B . 
H 4 HOH 27  427 127 HOH HOH B . 
H 4 HOH 28  428 104 HOH HOH B . 
H 4 HOH 29  429 191 HOH HOH B . 
H 4 HOH 30  430 231 HOH HOH B . 
H 4 HOH 31  431 27  HOH HOH B . 
H 4 HOH 32  432 169 HOH HOH B . 
H 4 HOH 33  433 135 HOH HOH B . 
H 4 HOH 34  434 68  HOH HOH B . 
H 4 HOH 35  435 21  HOH HOH B . 
H 4 HOH 36  436 150 HOH HOH B . 
H 4 HOH 37  437 39  HOH HOH B . 
H 4 HOH 38  438 156 HOH HOH B . 
H 4 HOH 39  439 161 HOH HOH B . 
H 4 HOH 40  440 145 HOH HOH B . 
H 4 HOH 41  441 143 HOH HOH B . 
H 4 HOH 42  442 189 HOH HOH B . 
H 4 HOH 43  443 220 HOH HOH B . 
H 4 HOH 44  444 61  HOH HOH B . 
H 4 HOH 45  445 166 HOH HOH B . 
H 4 HOH 46  446 6   HOH HOH B . 
H 4 HOH 47  447 206 HOH HOH B . 
H 4 HOH 48  448 60  HOH HOH B . 
H 4 HOH 49  449 23  HOH HOH B . 
H 4 HOH 50  450 304 HOH HOH B . 
H 4 HOH 51  451 134 HOH HOH B . 
H 4 HOH 52  452 89  HOH HOH B . 
H 4 HOH 53  453 173 HOH HOH B . 
H 4 HOH 54  454 117 HOH HOH B . 
H 4 HOH 55  455 114 HOH HOH B . 
H 4 HOH 56  456 50  HOH HOH B . 
H 4 HOH 57  457 336 HOH HOH B . 
H 4 HOH 58  458 102 HOH HOH B . 
H 4 HOH 59  459 340 HOH HOH B . 
H 4 HOH 60  460 9   HOH HOH B . 
H 4 HOH 61  461 5   HOH HOH B . 
H 4 HOH 62  462 200 HOH HOH B . 
H 4 HOH 63  463 99  HOH HOH B . 
H 4 HOH 64  464 136 HOH HOH B . 
H 4 HOH 65  465 85  HOH HOH B . 
H 4 HOH 66  466 82  HOH HOH B . 
H 4 HOH 67  467 131 HOH HOH B . 
H 4 HOH 68  468 158 HOH HOH B . 
H 4 HOH 69  469 313 HOH HOH B . 
H 4 HOH 70  470 94  HOH HOH B . 
H 4 HOH 71  471 151 HOH HOH B . 
H 4 HOH 72  472 152 HOH HOH B . 
H 4 HOH 73  473 44  HOH HOH B . 
H 4 HOH 74  474 324 HOH HOH B . 
H 4 HOH 75  475 63  HOH HOH B . 
H 4 HOH 76  476 98  HOH HOH B . 
H 4 HOH 77  477 248 HOH HOH B . 
H 4 HOH 78  478 308 HOH HOH B . 
H 4 HOH 79  479 235 HOH HOH B . 
H 4 HOH 80  480 123 HOH HOH B . 
H 4 HOH 81  481 81  HOH HOH B . 
H 4 HOH 82  482 305 HOH HOH B . 
H 4 HOH 83  483 37  HOH HOH B . 
H 4 HOH 84  484 211 HOH HOH B . 
H 4 HOH 85  485 170 HOH HOH B . 
H 4 HOH 86  486 319 HOH HOH B . 
H 4 HOH 87  487 334 HOH HOH B . 
H 4 HOH 88  488 306 HOH HOH B . 
H 4 HOH 89  489 219 HOH HOH B . 
H 4 HOH 90  490 103 HOH HOH B . 
H 4 HOH 91  491 83  HOH HOH B . 
H 4 HOH 92  492 75  HOH HOH B . 
H 4 HOH 93  493 30  HOH HOH B . 
H 4 HOH 94  494 301 HOH HOH B . 
H 4 HOH 95  495 217 HOH HOH B . 
H 4 HOH 96  496 119 HOH HOH B . 
H 4 HOH 97  497 110 HOH HOH B . 
H 4 HOH 98  498 216 HOH HOH B . 
H 4 HOH 99  499 116 HOH HOH B . 
H 4 HOH 100 500 121 HOH HOH B . 
H 4 HOH 101 501 199 HOH HOH B . 
H 4 HOH 102 502 113 HOH HOH B . 
H 4 HOH 103 503 323 HOH HOH B . 
H 4 HOH 104 504 263 HOH HOH B . 
H 4 HOH 105 505 11  HOH HOH B . 
H 4 HOH 106 506 43  HOH HOH B . 
H 4 HOH 107 507 250 HOH HOH B . 
H 4 HOH 108 508 195 HOH HOH B . 
H 4 HOH 109 509 198 HOH HOH B . 
H 4 HOH 110 510 344 HOH HOH B . 
H 4 HOH 111 511 46  HOH HOH B . 
H 4 HOH 112 512 318 HOH HOH B . 
H 4 HOH 113 513 343 HOH HOH B . 
H 4 HOH 114 514 266 HOH HOH B . 
H 4 HOH 115 515 223 HOH HOH B . 
H 4 HOH 116 516 332 HOH HOH B . 
H 4 HOH 117 517 130 HOH HOH B . 
H 4 HOH 118 518 314 HOH HOH B . 
H 4 HOH 119 519 326 HOH HOH B . 
H 4 HOH 120 520 154 HOH HOH B . 
H 4 HOH 121 521 310 HOH HOH B . 
H 4 HOH 122 522 153 HOH HOH B . 
H 4 HOH 123 523 192 HOH HOH B . 
H 4 HOH 124 524 327 HOH HOH B . 
H 4 HOH 125 525 141 HOH HOH B . 
H 4 HOH 126 526 312 HOH HOH B . 
H 4 HOH 127 527 140 HOH HOH B . 
H 4 HOH 128 528 321 HOH HOH B . 
H 4 HOH 129 529 264 HOH HOH B . 
H 4 HOH 130 530 142 HOH HOH B . 
H 4 HOH 131 531 190 HOH HOH B . 
H 4 HOH 132 532 338 HOH HOH B . 
H 4 HOH 133 533 245 HOH HOH B . 
H 4 HOH 134 534 315 HOH HOH B . 
H 4 HOH 135 535 317 HOH HOH B . 
H 4 HOH 136 536 246 HOH HOH B . 
H 4 HOH 137 537 311 HOH HOH B . 
H 4 HOH 138 538 193 HOH HOH B . 
H 4 HOH 139 539 309 HOH HOH B . 
H 4 HOH 140 540 328 HOH HOH B . 
H 4 HOH 141 541 341 HOH HOH B . 
H 4 HOH 142 542 227 HOH HOH B . 
H 4 HOH 143 543 251 HOH HOH B . 
H 4 HOH 144 544 214 HOH HOH B . 
H 4 HOH 145 545 225 HOH HOH B . 
H 4 HOH 146 546 187 HOH HOH B . 
H 4 HOH 147 547 238 HOH HOH B . 
H 4 HOH 148 548 236 HOH HOH B . 
H 4 HOH 149 549 342 HOH HOH B . 
H 4 HOH 150 550 138 HOH HOH B . 
H 4 HOH 151 551 329 HOH HOH B . 
H 4 HOH 152 552 222 HOH HOH B . 
H 4 HOH 153 553 302 HOH HOH B . 
H 4 HOH 154 554 335 HOH HOH B . 
H 4 HOH 155 555 330 HOH HOH B . 
H 4 HOH 156 556 157 HOH HOH B . 
H 4 HOH 157 557 234 HOH HOH B . 
H 4 HOH 158 558 203 HOH HOH B . 
H 4 HOH 159 559 237 HOH HOH B . 
H 4 HOH 160 560 228 HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLU 92  ? CD  ? A GLU 92  CD  
2  1 Y 1 A GLU 92  ? OE1 ? A GLU 92  OE1 
3  1 Y 1 A GLU 92  ? OE2 ? A GLU 92  OE2 
4  1 Y 1 A ARG 157 ? CZ  ? A ARG 157 CZ  
5  1 Y 1 A ARG 157 ? NH1 ? A ARG 157 NH1 
6  1 Y 1 A ARG 157 ? NH2 ? A ARG 157 NH2 
7  1 Y 1 A ASP 164 ? CG  ? A ASP 164 CG  
8  1 Y 1 A ASP 164 ? OD1 ? A ASP 164 OD1 
9  1 Y 1 A ASP 164 ? OD2 ? A ASP 164 OD2 
10 1 Y 1 A GLU 225 ? CG  ? A GLU 225 CG  
11 1 Y 1 A GLU 225 ? CD  ? A GLU 225 CD  
12 1 Y 1 A GLU 225 ? OE1 ? A GLU 225 OE1 
13 1 Y 1 A GLU 225 ? OE2 ? A GLU 225 OE2 
14 1 Y 1 A TRP 246 ? CG  ? A TRP 246 CG  
15 1 Y 1 A TRP 246 ? CD1 ? A TRP 246 CD1 
16 1 Y 1 A TRP 246 ? CD2 ? A TRP 246 CD2 
17 1 Y 1 A TRP 246 ? NE1 ? A TRP 246 NE1 
18 1 Y 1 A TRP 246 ? CE2 ? A TRP 246 CE2 
19 1 Y 1 A TRP 246 ? CE3 ? A TRP 246 CE3 
20 1 Y 1 A TRP 246 ? CZ2 ? A TRP 246 CZ2 
21 1 Y 1 A TRP 246 ? CZ3 ? A TRP 246 CZ3 
22 1 Y 1 A TRP 246 ? CH2 ? A TRP 246 CH2 
23 1 Y 1 A ASP 316 ? CG  ? A ASP 316 CG  
24 1 Y 1 A ASP 316 ? OD1 ? A ASP 316 OD1 
25 1 Y 1 A ASP 316 ? OD2 ? A ASP 316 OD2 
26 1 Y 1 A GLN 326 ? CG  ? A GLN 326 CG  
27 1 Y 1 A GLN 326 ? CD  ? A GLN 326 CD  
28 1 Y 1 A GLN 326 ? OE1 ? A GLN 326 OE1 
29 1 Y 1 A GLN 326 ? NE2 ? A GLN 326 NE2 
30 1 Y 1 B LYS 226 ? CD  ? B LYS 226 CD  
31 1 Y 1 B LYS 226 ? CE  ? B LYS 226 CE  
32 1 Y 1 B LYS 226 ? NZ  ? B LYS 226 NZ  
33 1 Y 1 B GLU 288 ? CG  ? B GLU 288 CG  
34 1 Y 1 B GLU 288 ? CD  ? B GLU 288 CD  
35 1 Y 1 B GLU 288 ? OE1 ? B GLU 288 OE1 
36 1 Y 1 B GLU 288 ? OE2 ? B GLU 288 OE2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.20_4444 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .         2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .         3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .         4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9C7L 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     181.521 
_cell.length_a_esd                 ? 
_cell.length_b                     181.521 
_cell.length_b_esd                 ? 
_cell.length_c                     55.763 
_cell.length_c_esd                 ? 
_cell.volume                       1591221.041 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9C7L 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                173 
_symmetry.space_group_name_Hall            'P 6c' 
_symmetry.space_group_name_H-M             'P 63' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9C7L 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.48 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          64.70 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '100 mM HEPES, pH 7.5, containing 2 M ammonium sulfate and 2% PEG400' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            296 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-03-12 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.979 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 24-ID-E' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.979 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   24-ID-E 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          46.62 
_reflns.entry_id                                       9C7L 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.2 
_reflns.d_resolution_low                               20 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     53642 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                20.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          16.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1.0 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.119 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.2 
_reflns_shell.d_res_low                                     2.27 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.1 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4642 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               21.3 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.8 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          100 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.86 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               52.04 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9C7L 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.20 
_refine.ls_d_res_low                             19.84 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     53622 
_refine.ls_number_reflns_R_free                  2713 
_refine.ls_number_reflns_R_work                  50909 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.98 
_refine.ls_percent_reflns_R_free                 5.06 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1859 
_refine.ls_R_factor_R_free                       0.2130 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1845 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 24.2809 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2639 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.20 
_refine_hist.d_res_low                        19.84 
_refine_hist.number_atoms_solvent             336 
_refine_hist.number_atoms_total               5359 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4995 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         28 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0023  ? 5157 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.5007  ? 7006 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0356  ? 731  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0051  ? 937  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 14.0387 ? 1898 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.20 2.24  . . 148 2681 99.96  . . . . 0.2662 . . . . . . . . . . . 0.3046 
'X-RAY DIFFRACTION' 2.24 2.28  . . 125 2641 100.00 . . . . 0.2564 . . . . . . . . . . . 0.3273 
'X-RAY DIFFRACTION' 2.28 2.33  . . 131 2692 99.96  . . . . 0.2429 . . . . . . . . . . . 0.3033 
'X-RAY DIFFRACTION' 2.33 2.38  . . 147 2620 100.00 . . . . 0.2297 . . . . . . . . . . . 0.2735 
'X-RAY DIFFRACTION' 2.38 2.44  . . 169 2661 100.00 . . . . 0.2257 . . . . . . . . . . . 0.2620 
'X-RAY DIFFRACTION' 2.44 2.50  . . 139 2644 99.96  . . . . 0.2198 . . . . . . . . . . . 0.2782 
'X-RAY DIFFRACTION' 2.50 2.56  . . 138 2664 100.00 . . . . 0.2175 . . . . . . . . . . . 0.2901 
'X-RAY DIFFRACTION' 2.56 2.64  . . 176 2643 100.00 . . . . 0.2123 . . . . . . . . . . . 0.2669 
'X-RAY DIFFRACTION' 2.64 2.72  . . 112 2679 100.00 . . . . 0.2170 . . . . . . . . . . . 0.2259 
'X-RAY DIFFRACTION' 2.72 2.82  . . 134 2680 100.00 . . . . 0.2077 . . . . . . . . . . . 0.2355 
'X-RAY DIFFRACTION' 2.82 2.93  . . 142 2688 99.96  . . . . 0.1998 . . . . . . . . . . . 0.2235 
'X-RAY DIFFRACTION' 2.93 3.07  . . 132 2659 100.00 . . . . 0.2044 . . . . . . . . . . . 0.2705 
'X-RAY DIFFRACTION' 3.07 3.23  . . 169 2662 99.96  . . . . 0.1989 . . . . . . . . . . . 0.2485 
'X-RAY DIFFRACTION' 3.23 3.43  . . 134 2690 100.00 . . . . 0.1912 . . . . . . . . . . . 0.2470 
'X-RAY DIFFRACTION' 3.43 3.69  . . 143 2682 99.96  . . . . 0.1665 . . . . . . . . . . . 0.2025 
'X-RAY DIFFRACTION' 3.69 4.06  . . 135 2694 100.00 . . . . 0.1613 . . . . . . . . . . . 0.1717 
'X-RAY DIFFRACTION' 4.06 4.64  . . 145 2724 100.00 . . . . 0.1521 . . . . . . . . . . . 0.1503 
'X-RAY DIFFRACTION' 4.64 5.82  . . 156 2694 100.00 . . . . 0.1713 . . . . . . . . . . . 0.2040 
'X-RAY DIFFRACTION' 5.82 19.84 . . 138 2811 99.90  . . . . 0.1730 . . . . . . . . . . . 0.1805 
# 
_struct.entry_id                     9C7L 
_struct.title                        
'Crystal structure of pentalenene synthase variant F76A complexed with 2-fluorofarnesyl diphosphate' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9C7L 
_struct_keywords.text            
'Terpene synthase, Cyclase, Sesquiterpene synthase, complex, Inhibitors, Fluoro analog, METAL BINDING PROTEIN' 
_struct_keywords.pdbx_keywords   'METAL BINDING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
H N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    PENA_STREX 
_struct_ref.pdbx_db_accession          Q55012 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MPQDVDFHIPLPGRQSPDHARAEAEQLAWPRSLGLIRSDAAAERHLRGGYADLASRFYPHATGADLDLGVDLMSWFFLFD
DLFDGPRGENPEDTKQLTDQVAAALDGPLPDTAPPIAHGFADIWRRTCEGMTPAWCARSARHWRNYFDGYVDEAESRFWN
APCDSAAQYLAMRRHTIGVQPTVDLAERAGRFEVPHRVFDSAVMSAMLQIAVDVNLLLNDIASLEKEEARGEQNNMVMIL
RREHGWSKSRSVSHMQNEVRARLEQYLLLESCLPKVGEIYQLDTAEREALERYRTDAVRTVIRGSYDWHRSSGRYDAEFA
LAAGAQGYLEELGSSAH
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9C7L A 1 ? 337 ? Q55012 1 ? 337 ? 1 337 
2 1 9C7L B 1 ? 337 ? Q55012 1 ? 337 ? 1 337 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9C7L ALA A 76 ? UNP Q55012 PHE 76 'engineered mutation' 76 1 
2 9C7L ALA B 76 ? UNP Q55012 PHE 76 'engineered mutation' 76 2 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,D,E,F,G 
2 1 B,H         
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 18  ? GLU A 25  ? ASP A 18  GLU A 25  1 ? 8  
HELX_P HELX_P2  AA2 LEU A 27  ? LEU A 33  ? LEU A 27  LEU A 33  1 ? 7  
HELX_P HELX_P3  AA3 SER A 38  ? ARG A 47  ? SER A 38  ARG A 47  1 ? 10 
HELX_P HELX_P4  AA4 GLY A 49  ? TYR A 58  ? GLY A 49  TYR A 58  1 ? 10 
HELX_P HELX_P5  AA5 THR A 62  ? LEU A 82  ? THR A 62  LEU A 82  1 ? 21 
HELX_P HELX_P6  AA6 PHE A 83  ? ASP A 84  ? PHE A 83  ASP A 84  5 ? 2  
HELX_P HELX_P7  AA7 GLY A 85  ? GLU A 89  ? GLY A 85  GLU A 89  5 ? 5  
HELX_P HELX_P8  AA8 ASN A 90  ? ALA A 103 ? ASN A 90  ALA A 103 1 ? 14 
HELX_P HELX_P9  AA9 ALA A 104 ? ASP A 106 ? ALA A 104 ASP A 106 5 ? 3  
HELX_P HELX_P10 AB1 PRO A 114 ? GLU A 129 ? PRO A 114 GLU A 129 1 ? 16 
HELX_P HELX_P11 AB2 THR A 132 ? TRP A 159 ? THR A 132 TRP A 159 1 ? 28 
HELX_P HELX_P12 AB3 SER A 165 ? ILE A 177 ? SER A 165 ILE A 177 1 ? 13 
HELX_P HELX_P13 AB4 GLY A 178 ? ARG A 191 ? GLY A 178 ARG A 191 1 ? 14 
HELX_P HELX_P14 AB5 PRO A 195 ? ASP A 200 ? PRO A 195 ASP A 200 1 ? 6  
HELX_P HELX_P15 AB6 SER A 201 ? SER A 223 ? SER A 201 SER A 223 1 ? 23 
HELX_P HELX_P16 AB7 SER A 223 ? ARG A 230 ? SER A 223 ARG A 230 1 ? 8  
HELX_P HELX_P17 AB8 ASN A 235 ? HIS A 244 ? ASN A 235 HIS A 244 1 ? 10 
HELX_P HELX_P18 AB9 SER A 247 ? SER A 271 ? SER A 247 SER A 271 1 ? 25 
HELX_P HELX_P19 AC1 CYS A 272 ? TYR A 280 ? CYS A 272 TYR A 280 1 ? 9  
HELX_P HELX_P20 AC2 ASP A 283 ? ALA A 297 ? ASP A 283 ALA A 297 1 ? 15 
HELX_P HELX_P21 AC3 ALA A 297 ? SER A 312 ? ALA A 297 SER A 312 1 ? 16 
HELX_P HELX_P22 AC4 GLY A 313 ? ASP A 316 ? GLY A 313 ASP A 316 5 ? 4  
HELX_P HELX_P23 AC5 LEU A 329 ? SER A 334 ? LEU A 329 SER A 334 5 ? 6  
HELX_P HELX_P24 AC6 ASP B 18  ? GLU B 25  ? ASP B 18  GLU B 25  1 ? 8  
HELX_P HELX_P25 AC7 LEU B 27  ? LEU B 33  ? LEU B 27  LEU B 33  1 ? 7  
HELX_P HELX_P26 AC8 SER B 38  ? GLY B 48  ? SER B 38  GLY B 48  1 ? 11 
HELX_P HELX_P27 AC9 GLY B 49  ? TYR B 58  ? GLY B 49  TYR B 58  1 ? 10 
HELX_P HELX_P28 AD1 THR B 62  ? LEU B 82  ? THR B 62  LEU B 82  1 ? 21 
HELX_P HELX_P29 AD2 PHE B 83  ? ASP B 84  ? PHE B 83  ASP B 84  5 ? 2  
HELX_P HELX_P30 AD3 GLY B 85  ? GLU B 89  ? GLY B 85  GLU B 89  5 ? 5  
HELX_P HELX_P31 AD4 ASN B 90  ? ALA B 103 ? ASN B 90  ALA B 103 1 ? 14 
HELX_P HELX_P32 AD5 ALA B 104 ? ASP B 106 ? ALA B 104 ASP B 106 5 ? 3  
HELX_P HELX_P33 AD6 PRO B 114 ? GLU B 129 ? PRO B 114 GLU B 129 1 ? 16 
HELX_P HELX_P34 AD7 THR B 132 ? TRP B 159 ? THR B 132 TRP B 159 1 ? 28 
HELX_P HELX_P35 AD8 SER B 165 ? ILE B 177 ? SER B 165 ILE B 177 1 ? 13 
HELX_P HELX_P36 AD9 GLY B 178 ? ARG B 191 ? GLY B 178 ARG B 191 1 ? 14 
HELX_P HELX_P37 AE1 PRO B 195 ? ASP B 200 ? PRO B 195 ASP B 200 1 ? 6  
HELX_P HELX_P38 AE2 SER B 201 ? SER B 223 ? SER B 201 SER B 223 1 ? 23 
HELX_P HELX_P39 AE3 SER B 223 ? ARG B 230 ? SER B 223 ARG B 230 1 ? 8  
HELX_P HELX_P40 AE4 ASN B 235 ? GLY B 245 ? ASN B 235 GLY B 245 1 ? 11 
HELX_P HELX_P41 AE5 SER B 247 ? SER B 271 ? SER B 247 SER B 271 1 ? 25 
HELX_P HELX_P42 AE6 CYS B 272 ? TYR B 280 ? CYS B 272 TYR B 280 1 ? 9  
HELX_P HELX_P43 AE7 ASP B 283 ? ALA B 297 ? ASP B 283 ALA B 297 1 ? 15 
HELX_P HELX_P44 AE8 ALA B 297 ? SER B 311 ? ALA B 297 SER B 311 1 ? 15 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A ASP 80  OD2 ? ? ? 1_555 D MG  . MG ? ? A ASP 80  A MG  402 1_555 ? ? ? ? ? ? ? 2.373 ? ? 
metalc2  metalc ? ? A ASP 80  OD1 ? ? ? 1_555 F MG  . MG ? ? A ASP 80  A MG  404 1_555 ? ? ? ? ? ? ? 2.497 ? ? 
metalc3  metalc ? ? A ASN 219 OD1 ? ? ? 1_555 E MG  . MG ? ? A ASN 219 A MG  403 1_555 ? ? ? ? ? ? ? 2.359 ? ? 
metalc4  metalc ? ? A SER 223 OG  ? ? ? 1_555 E MG  . MG ? ? A SER 223 A MG  403 1_555 ? ? ? ? ? ? ? 2.646 ? ? 
metalc5  metalc ? ? A GLU 227 OE2 ? ? ? 1_555 E MG  . MG ? ? A GLU 227 A MG  403 1_555 ? ? ? ? ? ? ? 2.664 ? ? 
metalc6  metalc ? ? C FPF .   O2A ? ? ? 1_555 D MG  . MG ? ? A FPF 401 A MG  402 1_555 ? ? ? ? ? ? ? 2.536 ? ? 
metalc7  metalc ? ? C FPF .   O2B ? ? ? 1_555 D MG  . MG ? ? A FPF 401 A MG  402 1_555 ? ? ? ? ? ? ? 2.318 ? ? 
metalc8  metalc ? ? C FPF .   O1A ? ? ? 1_555 E MG  . MG ? ? A FPF 401 A MG  403 1_555 ? ? ? ? ? ? ? 2.527 ? ? 
metalc9  metalc ? ? C FPF .   O3A ? ? ? 1_555 E MG  . MG ? ? A FPF 401 A MG  403 1_555 ? ? ? ? ? ? ? 2.701 ? ? 
metalc10 metalc ? ? C FPF .   O2A ? ? ? 1_555 F MG  . MG ? ? A FPF 401 A MG  404 1_555 ? ? ? ? ? ? ? 2.897 ? ? 
metalc11 metalc ? ? D MG  .   MG  ? ? ? 1_555 G HOH . O  ? ? A MG  402 A HOH 537 1_555 ? ? ? ? ? ? ? 2.068 ? ? 
metalc12 metalc ? ? D MG  .   MG  ? ? ? 1_555 G HOH . O  ? ? A MG  402 A HOH 639 1_555 ? ? ? ? ? ? ? 2.272 ? ? 
metalc13 metalc ? ? E MG  .   MG  ? ? ? 1_555 G HOH . O  ? ? A MG  403 A HOH 547 1_555 ? ? ? ? ? ? ? 2.779 ? ? 
metalc14 metalc ? ? F MG  .   MG  ? ? ? 1_555 G HOH . O  ? ? A MG  404 A HOH 588 1_555 ? ? ? ? ? ? ? 2.497 ? ? 
metalc15 metalc ? ? F MG  .   MG  ? ? ? 1_555 G HOH . O  ? ? A MG  404 A HOH 614 1_555 ? ? ? ? ? ? ? 2.730 ? ? 
metalc16 metalc ? ? F MG  .   MG  ? ? ? 1_555 G HOH . O  ? ? A MG  404 A HOH 642 1_555 ? ? ? ? ? ? ? 2.875 ? ? 
metalc17 metalc ? ? F MG  .   MG  ? ? ? 1_555 G HOH . O  ? ? A MG  404 A HOH 662 1_555 ? ? ? ? ? ? ? 2.637 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD2 ? A ASP 80  ? A ASP 80  ? 1_555 MG ? D MG . ? A MG 402 ? 1_555 O2A ? C FPF .   ? A FPF 401 ? 1_555 81.3  ? 
2  OD2 ? A ASP 80  ? A ASP 80  ? 1_555 MG ? D MG . ? A MG 402 ? 1_555 O2B ? C FPF .   ? A FPF 401 ? 1_555 90.8  ? 
3  O2A ? C FPF .   ? A FPF 401 ? 1_555 MG ? D MG . ? A MG 402 ? 1_555 O2B ? C FPF .   ? A FPF 401 ? 1_555 69.4  ? 
4  OD2 ? A ASP 80  ? A ASP 80  ? 1_555 MG ? D MG . ? A MG 402 ? 1_555 O   ? G HOH .   ? A HOH 537 ? 1_555 89.4  ? 
5  O2A ? C FPF .   ? A FPF 401 ? 1_555 MG ? D MG . ? A MG 402 ? 1_555 O   ? G HOH .   ? A HOH 537 ? 1_555 161.9 ? 
6  O2B ? C FPF .   ? A FPF 401 ? 1_555 MG ? D MG . ? A MG 402 ? 1_555 O   ? G HOH .   ? A HOH 537 ? 1_555 95.5  ? 
7  OD2 ? A ASP 80  ? A ASP 80  ? 1_555 MG ? D MG . ? A MG 402 ? 1_555 O   ? G HOH .   ? A HOH 639 ? 1_555 157.6 ? 
8  O2A ? C FPF .   ? A FPF 401 ? 1_555 MG ? D MG . ? A MG 402 ? 1_555 O   ? G HOH .   ? A HOH 639 ? 1_555 81.2  ? 
9  O2B ? C FPF .   ? A FPF 401 ? 1_555 MG ? D MG . ? A MG 402 ? 1_555 O   ? G HOH .   ? A HOH 639 ? 1_555 95.9  ? 
10 O   ? G HOH .   ? A HOH 537 ? 1_555 MG ? D MG . ? A MG 402 ? 1_555 O   ? G HOH .   ? A HOH 639 ? 1_555 111.1 ? 
11 OD1 ? A ASP 80  ? A ASP 80  ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O2A ? C FPF .   ? A FPF 401 ? 1_555 85.8  ? 
12 OD1 ? A ASP 80  ? A ASP 80  ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 588 ? 1_555 89.4  ? 
13 O2A ? C FPF .   ? A FPF 401 ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 588 ? 1_555 108.6 ? 
14 OD1 ? A ASP 80  ? A ASP 80  ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 614 ? 1_555 152.0 ? 
15 O2A ? C FPF .   ? A FPF 401 ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 614 ? 1_555 66.2  ? 
16 O   ? G HOH .   ? A HOH 588 ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 614 ? 1_555 99.3  ? 
17 OD1 ? A ASP 80  ? A ASP 80  ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 642 ? 1_555 114.4 ? 
18 O2A ? C FPF .   ? A FPF 401 ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 642 ? 1_555 159.0 ? 
19 O   ? G HOH .   ? A HOH 588 ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 642 ? 1_555 78.8  ? 
20 O   ? G HOH .   ? A HOH 614 ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 642 ? 1_555 93.4  ? 
21 OD1 ? A ASP 80  ? A ASP 80  ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 662 ? 1_555 147.7 ? 
22 O2A ? C FPF .   ? A FPF 401 ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 662 ? 1_555 114.7 ? 
23 O   ? G HOH .   ? A HOH 588 ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 662 ? 1_555 61.2  ? 
24 O   ? G HOH .   ? A HOH 614 ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 662 ? 1_555 54.7  ? 
25 O   ? G HOH .   ? A HOH 642 ? 1_555 MG ? F MG . ? A MG 404 ? 1_555 O   ? G HOH .   ? A HOH 662 ? 1_555 50.6  ? 
26 OD1 ? A ASN 219 ? A ASN 219 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 OG  ? A SER 223 ? A SER 223 ? 1_555 95.8  ? 
27 OD1 ? A ASN 219 ? A ASN 219 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 OE2 ? A GLU 227 ? A GLU 227 ? 1_555 174.7 ? 
28 OG  ? A SER 223 ? A SER 223 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 OE2 ? A GLU 227 ? A GLU 227 ? 1_555 79.2  ? 
29 OD1 ? A ASN 219 ? A ASN 219 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 O1A ? C FPF .   ? A FPF 401 ? 1_555 99.4  ? 
30 OG  ? A SER 223 ? A SER 223 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 O1A ? C FPF .   ? A FPF 401 ? 1_555 154.1 ? 
31 OE2 ? A GLU 227 ? A GLU 227 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 O1A ? C FPF .   ? A FPF 401 ? 1_555 84.6  ? 
32 OD1 ? A ASN 219 ? A ASN 219 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 O3A ? C FPF .   ? A FPF 401 ? 1_555 84.7  ? 
33 OG  ? A SER 223 ? A SER 223 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 O3A ? C FPF .   ? A FPF 401 ? 1_555 102.0 ? 
34 OE2 ? A GLU 227 ? A GLU 227 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 O3A ? C FPF .   ? A FPF 401 ? 1_555 94.6  ? 
35 O1A ? C FPF .   ? A FPF 401 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 O3A ? C FPF .   ? A FPF 401 ? 1_555 59.0  ? 
36 OD1 ? A ASN 219 ? A ASN 219 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 O   ? G HOH .   ? A HOH 547 ? 1_555 118.4 ? 
37 OG  ? A SER 223 ? A SER 223 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 O   ? G HOH .   ? A HOH 547 ? 1_555 107.8 ? 
38 OE2 ? A GLU 227 ? A GLU 227 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 O   ? G HOH .   ? A HOH 547 ? 1_555 65.2  ? 
39 O1A ? C FPF .   ? A FPF 401 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 O   ? G HOH .   ? A HOH 547 ? 1_555 83.1  ? 
40 O3A ? C FPF .   ? A FPF 401 ? 1_555 MG ? E MG . ? A MG 403 ? 1_555 O   ? G HOH .   ? A HOH 547 ? 1_555 139.2 ? 
# 
_pdbx_entry_details.entry_id                   9C7L 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 SER A 247 ? ? -78.14  -169.33 
2 1 ARG B 37  ? ? -127.19 -55.06  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z        
2 x-y,x,z+1/2  
3 y,-x+y,z+1/2 
4 -y,x-y,z     
5 -x+y,-x,z    
6 -x,-y,z+1/2  
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A PRO 2   ? A PRO 2   
3  1 Y 1 A GLN 3   ? A GLN 3   
4  1 Y 1 A ALA 317 ? A ALA 317 
5  1 Y 1 A GLU 318 ? A GLU 318 
6  1 Y 1 A PHE 319 ? A PHE 319 
7  1 Y 1 A ALA 320 ? A ALA 320 
8  1 Y 1 A LEU 321 ? A LEU 321 
9  1 Y 1 A ALA 322 ? A ALA 322 
10 1 Y 1 A ALA 323 ? A ALA 323 
11 1 Y 1 A GLY 324 ? A GLY 324 
12 1 Y 1 A ALA 336 ? A ALA 336 
13 1 Y 1 A HIS 337 ? A HIS 337 
14 1 Y 1 B MET 1   ? B MET 1   
15 1 Y 1 B PRO 2   ? B PRO 2   
16 1 Y 1 B GLN 3   ? B GLN 3   
17 1 Y 1 B ASP 4   ? B ASP 4   
18 1 Y 1 B SER 312 ? B SER 312 
19 1 Y 1 B GLY 313 ? B GLY 313 
20 1 Y 1 B ARG 314 ? B ARG 314 
21 1 Y 1 B TYR 315 ? B TYR 315 
22 1 Y 1 B ASP 316 ? B ASP 316 
23 1 Y 1 B ALA 317 ? B ALA 317 
24 1 Y 1 B GLU 318 ? B GLU 318 
25 1 Y 1 B PHE 319 ? B PHE 319 
26 1 Y 1 B ALA 320 ? B ALA 320 
27 1 Y 1 B LEU 321 ? B LEU 321 
28 1 Y 1 B ALA 322 ? B ALA 322 
29 1 Y 1 B ALA 323 ? B ALA 323 
30 1 Y 1 B GLY 324 ? B GLY 324 
31 1 Y 1 B ALA 325 ? B ALA 325 
32 1 Y 1 B GLN 326 ? B GLN 326 
33 1 Y 1 B GLY 327 ? B GLY 327 
34 1 Y 1 B TYR 328 ? B TYR 328 
35 1 Y 1 B LEU 329 ? B LEU 329 
36 1 Y 1 B GLU 330 ? B GLU 330 
37 1 Y 1 B GLU 331 ? B GLU 331 
38 1 Y 1 B LEU 332 ? B LEU 332 
39 1 Y 1 B GLY 333 ? B GLY 333 
40 1 Y 1 B SER 334 ? B SER 334 
41 1 Y 1 B SER 335 ? B SER 335 
42 1 Y 1 B ALA 336 ? B ALA 336 
43 1 Y 1 B HIS 337 ? B HIS 337 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
FPF C1   C  N N 88  
FPF O1   O  N N 89  
FPF C2   C  N N 90  
FPF F    F  N N 91  
FPF C3   C  N N 92  
FPF C4   C  N N 93  
FPF C5   C  N N 94  
FPF C6   C  N N 95  
FPF C7   C  N N 96  
FPF C8   C  N N 97  
FPF C10  C  N N 98  
FPF C9   C  N N 99  
FPF C11  C  N N 100 
FPF C12  C  N N 101 
FPF C13  C  N N 102 
FPF C14  C  N N 103 
FPF C15  C  N N 104 
FPF P1   P  N R 105 
FPF O1A  O  N N 106 
FPF O2A  O  N N 107 
FPF O3A  O  N N 108 
FPF P2   P  N N 109 
FPF O1B  O  N N 110 
FPF O2B  O  N N 111 
FPF O3B  O  N N 112 
FPF H1   H  N N 113 
FPF H1A  H  N N 114 
FPF H4   H  N N 115 
FPF H4A  H  N N 116 
FPF H4B  H  N N 117 
FPF H5   H  N N 118 
FPF H5A  H  N N 119 
FPF H6   H  N N 120 
FPF H6A  H  N N 121 
FPF H7   H  N N 122 
FPF H10  H  N N 123 
FPF H10A H  N N 124 
FPF H10B H  N N 125 
FPF H9   H  N N 126 
FPF H9A  H  N N 127 
FPF H11  H  N N 128 
FPF H11A H  N N 129 
FPF H12  H  N N 130 
FPF H14  H  N N 131 
FPF H14A H  N N 132 
FPF H14B H  N N 133 
FPF H15  H  N N 134 
FPF H15A H  N N 135 
FPF H15B H  N N 136 
FPF HO2A H  N N 137 
FPF HO1B H  N N 138 
FPF HO2B H  N N 139 
GLN N    N  N N 140 
GLN CA   C  N S 141 
GLN C    C  N N 142 
GLN O    O  N N 143 
GLN CB   C  N N 144 
GLN CG   C  N N 145 
GLN CD   C  N N 146 
GLN OE1  O  N N 147 
GLN NE2  N  N N 148 
GLN OXT  O  N N 149 
GLN H    H  N N 150 
GLN H2   H  N N 151 
GLN HA   H  N N 152 
GLN HB2  H  N N 153 
GLN HB3  H  N N 154 
GLN HG2  H  N N 155 
GLN HG3  H  N N 156 
GLN HE21 H  N N 157 
GLN HE22 H  N N 158 
GLN HXT  H  N N 159 
GLU N    N  N N 160 
GLU CA   C  N S 161 
GLU C    C  N N 162 
GLU O    O  N N 163 
GLU CB   C  N N 164 
GLU CG   C  N N 165 
GLU CD   C  N N 166 
GLU OE1  O  N N 167 
GLU OE2  O  N N 168 
GLU OXT  O  N N 169 
GLU H    H  N N 170 
GLU H2   H  N N 171 
GLU HA   H  N N 172 
GLU HB2  H  N N 173 
GLU HB3  H  N N 174 
GLU HG2  H  N N 175 
GLU HG3  H  N N 176 
GLU HE2  H  N N 177 
GLU HXT  H  N N 178 
GLY N    N  N N 179 
GLY CA   C  N N 180 
GLY C    C  N N 181 
GLY O    O  N N 182 
GLY OXT  O  N N 183 
GLY H    H  N N 184 
GLY H2   H  N N 185 
GLY HA2  H  N N 186 
GLY HA3  H  N N 187 
GLY HXT  H  N N 188 
HIS N    N  N N 189 
HIS CA   C  N S 190 
HIS C    C  N N 191 
HIS O    O  N N 192 
HIS CB   C  N N 193 
HIS CG   C  Y N 194 
HIS ND1  N  Y N 195 
HIS CD2  C  Y N 196 
HIS CE1  C  Y N 197 
HIS NE2  N  Y N 198 
HIS OXT  O  N N 199 
HIS H    H  N N 200 
HIS H2   H  N N 201 
HIS HA   H  N N 202 
HIS HB2  H  N N 203 
HIS HB3  H  N N 204 
HIS HD1  H  N N 205 
HIS HD2  H  N N 206 
HIS HE1  H  N N 207 
HIS HE2  H  N N 208 
HIS HXT  H  N N 209 
HOH O    O  N N 210 
HOH H1   H  N N 211 
HOH H2   H  N N 212 
ILE N    N  N N 213 
ILE CA   C  N S 214 
ILE C    C  N N 215 
ILE O    O  N N 216 
ILE CB   C  N S 217 
ILE CG1  C  N N 218 
ILE CG2  C  N N 219 
ILE CD1  C  N N 220 
ILE OXT  O  N N 221 
ILE H    H  N N 222 
ILE H2   H  N N 223 
ILE HA   H  N N 224 
ILE HB   H  N N 225 
ILE HG12 H  N N 226 
ILE HG13 H  N N 227 
ILE HG21 H  N N 228 
ILE HG22 H  N N 229 
ILE HG23 H  N N 230 
ILE HD11 H  N N 231 
ILE HD12 H  N N 232 
ILE HD13 H  N N 233 
ILE HXT  H  N N 234 
LEU N    N  N N 235 
LEU CA   C  N S 236 
LEU C    C  N N 237 
LEU O    O  N N 238 
LEU CB   C  N N 239 
LEU CG   C  N N 240 
LEU CD1  C  N N 241 
LEU CD2  C  N N 242 
LEU OXT  O  N N 243 
LEU H    H  N N 244 
LEU H2   H  N N 245 
LEU HA   H  N N 246 
LEU HB2  H  N N 247 
LEU HB3  H  N N 248 
LEU HG   H  N N 249 
LEU HD11 H  N N 250 
LEU HD12 H  N N 251 
LEU HD13 H  N N 252 
LEU HD21 H  N N 253 
LEU HD22 H  N N 254 
LEU HD23 H  N N 255 
LEU HXT  H  N N 256 
LYS N    N  N N 257 
LYS CA   C  N S 258 
LYS C    C  N N 259 
LYS O    O  N N 260 
LYS CB   C  N N 261 
LYS CG   C  N N 262 
LYS CD   C  N N 263 
LYS CE   C  N N 264 
LYS NZ   N  N N 265 
LYS OXT  O  N N 266 
LYS H    H  N N 267 
LYS H2   H  N N 268 
LYS HA   H  N N 269 
LYS HB2  H  N N 270 
LYS HB3  H  N N 271 
LYS HG2  H  N N 272 
LYS HG3  H  N N 273 
LYS HD2  H  N N 274 
LYS HD3  H  N N 275 
LYS HE2  H  N N 276 
LYS HE3  H  N N 277 
LYS HZ1  H  N N 278 
LYS HZ2  H  N N 279 
LYS HZ3  H  N N 280 
LYS HXT  H  N N 281 
MET N    N  N N 282 
MET CA   C  N S 283 
MET C    C  N N 284 
MET O    O  N N 285 
MET CB   C  N N 286 
MET CG   C  N N 287 
MET SD   S  N N 288 
MET CE   C  N N 289 
MET OXT  O  N N 290 
MET H    H  N N 291 
MET H2   H  N N 292 
MET HA   H  N N 293 
MET HB2  H  N N 294 
MET HB3  H  N N 295 
MET HG2  H  N N 296 
MET HG3  H  N N 297 
MET HE1  H  N N 298 
MET HE2  H  N N 299 
MET HE3  H  N N 300 
MET HXT  H  N N 301 
MG  MG   MG N N 302 
PHE N    N  N N 303 
PHE CA   C  N S 304 
PHE C    C  N N 305 
PHE O    O  N N 306 
PHE CB   C  N N 307 
PHE CG   C  Y N 308 
PHE CD1  C  Y N 309 
PHE CD2  C  Y N 310 
PHE CE1  C  Y N 311 
PHE CE2  C  Y N 312 
PHE CZ   C  Y N 313 
PHE OXT  O  N N 314 
PHE H    H  N N 315 
PHE H2   H  N N 316 
PHE HA   H  N N 317 
PHE HB2  H  N N 318 
PHE HB3  H  N N 319 
PHE HD1  H  N N 320 
PHE HD2  H  N N 321 
PHE HE1  H  N N 322 
PHE HE2  H  N N 323 
PHE HZ   H  N N 324 
PHE HXT  H  N N 325 
PRO N    N  N N 326 
PRO CA   C  N S 327 
PRO C    C  N N 328 
PRO O    O  N N 329 
PRO CB   C  N N 330 
PRO CG   C  N N 331 
PRO CD   C  N N 332 
PRO OXT  O  N N 333 
PRO H    H  N N 334 
PRO HA   H  N N 335 
PRO HB2  H  N N 336 
PRO HB3  H  N N 337 
PRO HG2  H  N N 338 
PRO HG3  H  N N 339 
PRO HD2  H  N N 340 
PRO HD3  H  N N 341 
PRO HXT  H  N N 342 
SER N    N  N N 343 
SER CA   C  N S 344 
SER C    C  N N 345 
SER O    O  N N 346 
SER CB   C  N N 347 
SER OG   O  N N 348 
SER OXT  O  N N 349 
SER H    H  N N 350 
SER H2   H  N N 351 
SER HA   H  N N 352 
SER HB2  H  N N 353 
SER HB3  H  N N 354 
SER HG   H  N N 355 
SER HXT  H  N N 356 
THR N    N  N N 357 
THR CA   C  N S 358 
THR C    C  N N 359 
THR O    O  N N 360 
THR CB   C  N R 361 
THR OG1  O  N N 362 
THR CG2  C  N N 363 
THR OXT  O  N N 364 
THR H    H  N N 365 
THR H2   H  N N 366 
THR HA   H  N N 367 
THR HB   H  N N 368 
THR HG1  H  N N 369 
THR HG21 H  N N 370 
THR HG22 H  N N 371 
THR HG23 H  N N 372 
THR HXT  H  N N 373 
TRP N    N  N N 374 
TRP CA   C  N S 375 
TRP C    C  N N 376 
TRP O    O  N N 377 
TRP CB   C  N N 378 
TRP CG   C  Y N 379 
TRP CD1  C  Y N 380 
TRP CD2  C  Y N 381 
TRP NE1  N  Y N 382 
TRP CE2  C  Y N 383 
TRP CE3  C  Y N 384 
TRP CZ2  C  Y N 385 
TRP CZ3  C  Y N 386 
TRP CH2  C  Y N 387 
TRP OXT  O  N N 388 
TRP H    H  N N 389 
TRP H2   H  N N 390 
TRP HA   H  N N 391 
TRP HB2  H  N N 392 
TRP HB3  H  N N 393 
TRP HD1  H  N N 394 
TRP HE1  H  N N 395 
TRP HE3  H  N N 396 
TRP HZ2  H  N N 397 
TRP HZ3  H  N N 398 
TRP HH2  H  N N 399 
TRP HXT  H  N N 400 
TYR N    N  N N 401 
TYR CA   C  N S 402 
TYR C    C  N N 403 
TYR O    O  N N 404 
TYR CB   C  N N 405 
TYR CG   C  Y N 406 
TYR CD1  C  Y N 407 
TYR CD2  C  Y N 408 
TYR CE1  C  Y N 409 
TYR CE2  C  Y N 410 
TYR CZ   C  Y N 411 
TYR OH   O  N N 412 
TYR OXT  O  N N 413 
TYR H    H  N N 414 
TYR H2   H  N N 415 
TYR HA   H  N N 416 
TYR HB2  H  N N 417 
TYR HB3  H  N N 418 
TYR HD1  H  N N 419 
TYR HD2  H  N N 420 
TYR HE1  H  N N 421 
TYR HE2  H  N N 422 
TYR HH   H  N N 423 
TYR HXT  H  N N 424 
VAL N    N  N N 425 
VAL CA   C  N S 426 
VAL C    C  N N 427 
VAL O    O  N N 428 
VAL CB   C  N N 429 
VAL CG1  C  N N 430 
VAL CG2  C  N N 431 
VAL OXT  O  N N 432 
VAL H    H  N N 433 
VAL H2   H  N N 434 
VAL HA   H  N N 435 
VAL HB   H  N N 436 
VAL HG11 H  N N 437 
VAL HG12 H  N N 438 
VAL HG13 H  N N 439 
VAL HG21 H  N N 440 
VAL HG22 H  N N 441 
VAL HG23 H  N N 442 
VAL HXT  H  N N 443 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
FPF O1  C1   sing N N 83  
FPF C1  C2   sing N N 84  
FPF C1  H1   sing N N 85  
FPF C1  H1A  sing N N 86  
FPF P1  O1   sing N N 87  
FPF C3  C2   doub N Z 88  
FPF C2  F    sing N N 89  
FPF C4  C3   sing N N 90  
FPF C3  C5   sing N N 91  
FPF C4  H4   sing N N 92  
FPF C4  H4A  sing N N 93  
FPF C4  H4B  sing N N 94  
FPF C6  C5   sing N N 95  
FPF C5  H5   sing N N 96  
FPF C5  H5A  sing N N 97  
FPF C7  C6   sing N N 98  
FPF C6  H6   sing N N 99  
FPF C6  H6A  sing N N 100 
FPF C8  C7   doub N E 101 
FPF C7  H7   sing N N 102 
FPF C9  C8   sing N N 103 
FPF C8  C10  sing N N 104 
FPF C10 H10  sing N N 105 
FPF C10 H10A sing N N 106 
FPF C10 H10B sing N N 107 
FPF C11 C9   sing N N 108 
FPF C9  H9   sing N N 109 
FPF C9  H9A  sing N N 110 
FPF C11 C12  sing N N 111 
FPF C11 H11  sing N N 112 
FPF C11 H11A sing N N 113 
FPF C13 C12  doub N N 114 
FPF C12 H12  sing N N 115 
FPF C15 C13  sing N N 116 
FPF C13 C14  sing N N 117 
FPF C14 H14  sing N N 118 
FPF C14 H14A sing N N 119 
FPF C14 H14B sing N N 120 
FPF C15 H15  sing N N 121 
FPF C15 H15A sing N N 122 
FPF C15 H15B sing N N 123 
FPF O1A P1   doub N N 124 
FPF O2A P1   sing N N 125 
FPF P1  O3A  sing N N 126 
FPF O2A HO2A sing N N 127 
FPF P2  O3A  sing N N 128 
FPF O3B P2   doub N N 129 
FPF P2  O1B  sing N N 130 
FPF P2  O2B  sing N N 131 
FPF O1B HO1B sing N N 132 
FPF O2B HO2B sing N N 133 
GLN N   CA   sing N N 134 
GLN N   H    sing N N 135 
GLN N   H2   sing N N 136 
GLN CA  C    sing N N 137 
GLN CA  CB   sing N N 138 
GLN CA  HA   sing N N 139 
GLN C   O    doub N N 140 
GLN C   OXT  sing N N 141 
GLN CB  CG   sing N N 142 
GLN CB  HB2  sing N N 143 
GLN CB  HB3  sing N N 144 
GLN CG  CD   sing N N 145 
GLN CG  HG2  sing N N 146 
GLN CG  HG3  sing N N 147 
GLN CD  OE1  doub N N 148 
GLN CD  NE2  sing N N 149 
GLN NE2 HE21 sing N N 150 
GLN NE2 HE22 sing N N 151 
GLN OXT HXT  sing N N 152 
GLU N   CA   sing N N 153 
GLU N   H    sing N N 154 
GLU N   H2   sing N N 155 
GLU CA  C    sing N N 156 
GLU CA  CB   sing N N 157 
GLU CA  HA   sing N N 158 
GLU C   O    doub N N 159 
GLU C   OXT  sing N N 160 
GLU CB  CG   sing N N 161 
GLU CB  HB2  sing N N 162 
GLU CB  HB3  sing N N 163 
GLU CG  CD   sing N N 164 
GLU CG  HG2  sing N N 165 
GLU CG  HG3  sing N N 166 
GLU CD  OE1  doub N N 167 
GLU CD  OE2  sing N N 168 
GLU OE2 HE2  sing N N 169 
GLU OXT HXT  sing N N 170 
GLY N   CA   sing N N 171 
GLY N   H    sing N N 172 
GLY N   H2   sing N N 173 
GLY CA  C    sing N N 174 
GLY CA  HA2  sing N N 175 
GLY CA  HA3  sing N N 176 
GLY C   O    doub N N 177 
GLY C   OXT  sing N N 178 
GLY OXT HXT  sing N N 179 
HIS N   CA   sing N N 180 
HIS N   H    sing N N 181 
HIS N   H2   sing N N 182 
HIS CA  C    sing N N 183 
HIS CA  CB   sing N N 184 
HIS CA  HA   sing N N 185 
HIS C   O    doub N N 186 
HIS C   OXT  sing N N 187 
HIS CB  CG   sing N N 188 
HIS CB  HB2  sing N N 189 
HIS CB  HB3  sing N N 190 
HIS CG  ND1  sing Y N 191 
HIS CG  CD2  doub Y N 192 
HIS ND1 CE1  doub Y N 193 
HIS ND1 HD1  sing N N 194 
HIS CD2 NE2  sing Y N 195 
HIS CD2 HD2  sing N N 196 
HIS CE1 NE2  sing Y N 197 
HIS CE1 HE1  sing N N 198 
HIS NE2 HE2  sing N N 199 
HIS OXT HXT  sing N N 200 
HOH O   H1   sing N N 201 
HOH O   H2   sing N N 202 
ILE N   CA   sing N N 203 
ILE N   H    sing N N 204 
ILE N   H2   sing N N 205 
ILE CA  C    sing N N 206 
ILE CA  CB   sing N N 207 
ILE CA  HA   sing N N 208 
ILE C   O    doub N N 209 
ILE C   OXT  sing N N 210 
ILE CB  CG1  sing N N 211 
ILE CB  CG2  sing N N 212 
ILE CB  HB   sing N N 213 
ILE CG1 CD1  sing N N 214 
ILE CG1 HG12 sing N N 215 
ILE CG1 HG13 sing N N 216 
ILE CG2 HG21 sing N N 217 
ILE CG2 HG22 sing N N 218 
ILE CG2 HG23 sing N N 219 
ILE CD1 HD11 sing N N 220 
ILE CD1 HD12 sing N N 221 
ILE CD1 HD13 sing N N 222 
ILE OXT HXT  sing N N 223 
LEU N   CA   sing N N 224 
LEU N   H    sing N N 225 
LEU N   H2   sing N N 226 
LEU CA  C    sing N N 227 
LEU CA  CB   sing N N 228 
LEU CA  HA   sing N N 229 
LEU C   O    doub N N 230 
LEU C   OXT  sing N N 231 
LEU CB  CG   sing N N 232 
LEU CB  HB2  sing N N 233 
LEU CB  HB3  sing N N 234 
LEU CG  CD1  sing N N 235 
LEU CG  CD2  sing N N 236 
LEU CG  HG   sing N N 237 
LEU CD1 HD11 sing N N 238 
LEU CD1 HD12 sing N N 239 
LEU CD1 HD13 sing N N 240 
LEU CD2 HD21 sing N N 241 
LEU CD2 HD22 sing N N 242 
LEU CD2 HD23 sing N N 243 
LEU OXT HXT  sing N N 244 
LYS N   CA   sing N N 245 
LYS N   H    sing N N 246 
LYS N   H2   sing N N 247 
LYS CA  C    sing N N 248 
LYS CA  CB   sing N N 249 
LYS CA  HA   sing N N 250 
LYS C   O    doub N N 251 
LYS C   OXT  sing N N 252 
LYS CB  CG   sing N N 253 
LYS CB  HB2  sing N N 254 
LYS CB  HB3  sing N N 255 
LYS CG  CD   sing N N 256 
LYS CG  HG2  sing N N 257 
LYS CG  HG3  sing N N 258 
LYS CD  CE   sing N N 259 
LYS CD  HD2  sing N N 260 
LYS CD  HD3  sing N N 261 
LYS CE  NZ   sing N N 262 
LYS CE  HE2  sing N N 263 
LYS CE  HE3  sing N N 264 
LYS NZ  HZ1  sing N N 265 
LYS NZ  HZ2  sing N N 266 
LYS NZ  HZ3  sing N N 267 
LYS OXT HXT  sing N N 268 
MET N   CA   sing N N 269 
MET N   H    sing N N 270 
MET N   H2   sing N N 271 
MET CA  C    sing N N 272 
MET CA  CB   sing N N 273 
MET CA  HA   sing N N 274 
MET C   O    doub N N 275 
MET C   OXT  sing N N 276 
MET CB  CG   sing N N 277 
MET CB  HB2  sing N N 278 
MET CB  HB3  sing N N 279 
MET CG  SD   sing N N 280 
MET CG  HG2  sing N N 281 
MET CG  HG3  sing N N 282 
MET SD  CE   sing N N 283 
MET CE  HE1  sing N N 284 
MET CE  HE2  sing N N 285 
MET CE  HE3  sing N N 286 
MET OXT HXT  sing N N 287 
PHE N   CA   sing N N 288 
PHE N   H    sing N N 289 
PHE N   H2   sing N N 290 
PHE CA  C    sing N N 291 
PHE CA  CB   sing N N 292 
PHE CA  HA   sing N N 293 
PHE C   O    doub N N 294 
PHE C   OXT  sing N N 295 
PHE CB  CG   sing N N 296 
PHE CB  HB2  sing N N 297 
PHE CB  HB3  sing N N 298 
PHE CG  CD1  doub Y N 299 
PHE CG  CD2  sing Y N 300 
PHE CD1 CE1  sing Y N 301 
PHE CD1 HD1  sing N N 302 
PHE CD2 CE2  doub Y N 303 
PHE CD2 HD2  sing N N 304 
PHE CE1 CZ   doub Y N 305 
PHE CE1 HE1  sing N N 306 
PHE CE2 CZ   sing Y N 307 
PHE CE2 HE2  sing N N 308 
PHE CZ  HZ   sing N N 309 
PHE OXT HXT  sing N N 310 
PRO N   CA   sing N N 311 
PRO N   CD   sing N N 312 
PRO N   H    sing N N 313 
PRO CA  C    sing N N 314 
PRO CA  CB   sing N N 315 
PRO CA  HA   sing N N 316 
PRO C   O    doub N N 317 
PRO C   OXT  sing N N 318 
PRO CB  CG   sing N N 319 
PRO CB  HB2  sing N N 320 
PRO CB  HB3  sing N N 321 
PRO CG  CD   sing N N 322 
PRO CG  HG2  sing N N 323 
PRO CG  HG3  sing N N 324 
PRO CD  HD2  sing N N 325 
PRO CD  HD3  sing N N 326 
PRO OXT HXT  sing N N 327 
SER N   CA   sing N N 328 
SER N   H    sing N N 329 
SER N   H2   sing N N 330 
SER CA  C    sing N N 331 
SER CA  CB   sing N N 332 
SER CA  HA   sing N N 333 
SER C   O    doub N N 334 
SER C   OXT  sing N N 335 
SER CB  OG   sing N N 336 
SER CB  HB2  sing N N 337 
SER CB  HB3  sing N N 338 
SER OG  HG   sing N N 339 
SER OXT HXT  sing N N 340 
THR N   CA   sing N N 341 
THR N   H    sing N N 342 
THR N   H2   sing N N 343 
THR CA  C    sing N N 344 
THR CA  CB   sing N N 345 
THR CA  HA   sing N N 346 
THR C   O    doub N N 347 
THR C   OXT  sing N N 348 
THR CB  OG1  sing N N 349 
THR CB  CG2  sing N N 350 
THR CB  HB   sing N N 351 
THR OG1 HG1  sing N N 352 
THR CG2 HG21 sing N N 353 
THR CG2 HG22 sing N N 354 
THR CG2 HG23 sing N N 355 
THR OXT HXT  sing N N 356 
TRP N   CA   sing N N 357 
TRP N   H    sing N N 358 
TRP N   H2   sing N N 359 
TRP CA  C    sing N N 360 
TRP CA  CB   sing N N 361 
TRP CA  HA   sing N N 362 
TRP C   O    doub N N 363 
TRP C   OXT  sing N N 364 
TRP CB  CG   sing N N 365 
TRP CB  HB2  sing N N 366 
TRP CB  HB3  sing N N 367 
TRP CG  CD1  doub Y N 368 
TRP CG  CD2  sing Y N 369 
TRP CD1 NE1  sing Y N 370 
TRP CD1 HD1  sing N N 371 
TRP CD2 CE2  doub Y N 372 
TRP CD2 CE3  sing Y N 373 
TRP NE1 CE2  sing Y N 374 
TRP NE1 HE1  sing N N 375 
TRP CE2 CZ2  sing Y N 376 
TRP CE3 CZ3  doub Y N 377 
TRP CE3 HE3  sing N N 378 
TRP CZ2 CH2  doub Y N 379 
TRP CZ2 HZ2  sing N N 380 
TRP CZ3 CH2  sing Y N 381 
TRP CZ3 HZ3  sing N N 382 
TRP CH2 HH2  sing N N 383 
TRP OXT HXT  sing N N 384 
TYR N   CA   sing N N 385 
TYR N   H    sing N N 386 
TYR N   H2   sing N N 387 
TYR CA  C    sing N N 388 
TYR CA  CB   sing N N 389 
TYR CA  HA   sing N N 390 
TYR C   O    doub N N 391 
TYR C   OXT  sing N N 392 
TYR CB  CG   sing N N 393 
TYR CB  HB2  sing N N 394 
TYR CB  HB3  sing N N 395 
TYR CG  CD1  doub Y N 396 
TYR CG  CD2  sing Y N 397 
TYR CD1 CE1  sing Y N 398 
TYR CD1 HD1  sing N N 399 
TYR CD2 CE2  doub Y N 400 
TYR CD2 HD2  sing N N 401 
TYR CE1 CZ   doub Y N 402 
TYR CE1 HE1  sing N N 403 
TYR CE2 CZ   sing Y N 404 
TYR CE2 HE2  sing N N 405 
TYR CZ  OH   sing N N 406 
TYR OH  HH   sing N N 407 
TYR OXT HXT  sing N N 408 
VAL N   CA   sing N N 409 
VAL N   H    sing N N 410 
VAL N   H2   sing N N 411 
VAL CA  C    sing N N 412 
VAL CA  CB   sing N N 413 
VAL CA  HA   sing N N 414 
VAL C   O    doub N N 415 
VAL C   OXT  sing N N 416 
VAL CB  CG1  sing N N 417 
VAL CB  CG2  sing N N 418 
VAL CB  HB   sing N N 419 
VAL CG1 HG11 sing N N 420 
VAL CG1 HG12 sing N N 421 
VAL CG1 HG13 sing N N 422 
VAL CG2 HG21 sing N N 423 
VAL CG2 HG22 sing N N 424 
VAL CG2 HG23 sing N N 425 
VAL OXT HXT  sing N N 426 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6WKD 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 63' 
_space_group.name_Hall        'P 6c' 
_space_group.IT_number        173 
_space_group.crystal_system   hexagonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9C7L 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.005509 
_atom_sites.fract_transf_matrix[1][2]   0.003181 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.006361 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.017933 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
F  ? ? 4.90428 4.07044 ? ? 12.99538 1.63651  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
MG ? ? 9.41153 2.53737 ? ? 2.59044  63.03566 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P  ? ? 9.51135 5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ASP A 1 4   ? 69.77576  3.46928   -29.13379 1.000 91.07972  ? 4   ASP A N   1 
ATOM   2    C  CA  . ASP A 1 4   ? 70.27357  2.47440   -28.18977 1.000 100.70211 ? 4   ASP A CA  1 
ATOM   3    C  C   . ASP A 1 4   ? 69.23754  2.14172   -27.12294 1.000 97.52499  ? 4   ASP A C   1 
ATOM   4    O  O   . ASP A 1 4   ? 68.15728  2.73202   -27.08200 1.000 97.38428  ? 4   ASP A O   1 
ATOM   5    C  CB  . ASP A 1 4   ? 71.56444  2.96111   -27.52532 1.000 97.19066  ? 4   ASP A CB  1 
ATOM   6    C  CG  . ASP A 1 4   ? 72.80759  2.37554   -28.16713 1.000 101.12684 ? 4   ASP A CG  1 
ATOM   7    O  OD1 . ASP A 1 4   ? 72.66849  1.58400   -29.12379 1.000 100.13655 ? 4   ASP A OD1 1 
ATOM   8    O  OD2 . ASP A 1 4   ? 73.92401  2.70234   -27.71146 1.000 93.45079  ? 4   ASP A OD2 1 
ATOM   9    N  N   . VAL A 1 5   ? 69.57994  1.18757   -26.25959 1.000 92.37569  ? 5   VAL A N   1 
ATOM   10   C  CA  . VAL A 1 5   ? 68.71733  0.76219   -25.16629 1.000 93.68039  ? 5   VAL A CA  1 
ATOM   11   C  C   . VAL A 1 5   ? 69.51993  0.78207   -23.87227 1.000 88.51735  ? 5   VAL A C   1 
ATOM   12   O  O   . VAL A 1 5   ? 70.72373  0.50438   -23.85820 1.000 83.41851  ? 5   VAL A O   1 
ATOM   13   C  CB  . VAL A 1 5   ? 68.11505  -0.63804  -25.41983 1.000 86.21169  ? 5   VAL A CB  1 
ATOM   14   C  CG1 . VAL A 1 5   ? 67.18935  -0.60957  -26.62753 1.000 80.70031  ? 5   VAL A CG1 1 
ATOM   15   C  CG2 . VAL A 1 5   ? 69.21644  -1.64939  -25.63038 1.000 83.74262  ? 5   VAL A CG2 1 
ATOM   16   N  N   . ASP A 1 6   ? 68.84353  1.11894   -22.77889 1.000 85.97306  ? 6   ASP A N   1 
ATOM   17   C  CA  . ASP A 1 6   ? 69.47984  1.25994   -21.47835 1.000 84.83929  ? 6   ASP A CA  1 
ATOM   18   C  C   . ASP A 1 6   ? 69.25845  0.01446   -20.62854 1.000 76.84739  ? 6   ASP A C   1 
ATOM   19   O  O   . ASP A 1 6   ? 68.23866  -0.67087  -20.74487 1.000 70.05058  ? 6   ASP A O   1 
ATOM   20   C  CB  . ASP A 1 6   ? 68.94841  2.49373   -20.74365 1.000 88.20602  ? 6   ASP A CB  1 
ATOM   21   C  CG  . ASP A 1 6   ? 69.43011  3.79374   -21.36295 1.000 93.83151  ? 6   ASP A CG  1 
ATOM   22   O  OD1 . ASP A 1 6   ? 70.61156  3.85959   -21.76406 1.000 94.26678  ? 6   ASP A OD1 1 
ATOM   23   O  OD2 . ASP A 1 6   ? 68.62883  4.74812   -21.45263 1.000 95.15902  ? 6   ASP A OD2 1 
ATOM   24   N  N   . PHE A 1 7   ? 70.23336  -0.27060  -19.76743 1.000 73.41559  ? 7   PHE A N   1 
ATOM   25   C  CA  . PHE A 1 7   ? 70.16620  -1.41125  -18.86808 1.000 65.03537  ? 7   PHE A CA  1 
ATOM   26   C  C   . PHE A 1 7   ? 70.59929  -0.99240  -17.47329 1.000 67.76269  ? 7   PHE A C   1 
ATOM   27   O  O   . PHE A 1 7   ? 71.38435  -0.05505  -17.30206 1.000 67.92012  ? 7   PHE A O   1 
ATOM   28   C  CB  . PHE A 1 7   ? 71.05011  -2.56907  -19.34060 1.000 65.54733  ? 7   PHE A CB  1 
ATOM   29   C  CG  . PHE A 1 7   ? 70.59880  -3.19062  -20.62457 1.000 68.15024  ? 7   PHE A CG  1 
ATOM   30   C  CD1 . PHE A 1 7   ? 69.62471  -4.17458  -20.62614 1.000 66.54784  ? 7   PHE A CD1 1 
ATOM   31   C  CD2 . PHE A 1 7   ? 71.15528  -2.79945  -21.83086 1.000 71.31597  ? 7   PHE A CD2 1 
ATOM   32   C  CE1 . PHE A 1 7   ? 69.21023  -4.75377  -21.80871 1.000 72.20061  ? 7   PHE A CE1 1 
ATOM   33   C  CE2 . PHE A 1 7   ? 70.74595  -3.37401  -23.01492 1.000 72.38921  ? 7   PHE A CE2 1 
ATOM   34   C  CZ  . PHE A 1 7   ? 69.77251  -4.35171  -23.00477 1.000 72.20839  ? 7   PHE A CZ  1 
ATOM   35   N  N   . HIS A 1 8   ? 70.08472  -1.71175  -16.47906 1.000 62.76099  ? 8   HIS A N   1 
ATOM   36   C  CA  . HIS A 1 8   ? 70.46360  -1.50740  -15.08387 1.000 64.39873  ? 8   HIS A CA  1 
ATOM   37   C  C   . HIS A 1 8   ? 71.73531  -2.30507  -14.81379 1.000 64.24094  ? 8   HIS A C   1 
ATOM   38   O  O   . HIS A 1 8   ? 71.68860  -3.51421  -14.56894 1.000 59.83289  ? 8   HIS A O   1 
ATOM   39   C  CB  . HIS A 1 8   ? 69.32744  -1.92566  -14.15685 1.000 58.87056  ? 8   HIS A CB  1 
ATOM   40   C  CG  . HIS A 1 8   ? 69.60879  -1.68544  -12.70628 1.000 65.07310  ? 8   HIS A CG  1 
ATOM   41   N  ND1 . HIS A 1 8   ? 70.20516  -0.53189  -12.24469 1.000 66.42920  ? 8   HIS A ND1 1 
ATOM   42   C  CD2 . HIS A 1 8   ? 69.36833  -2.44765  -11.61285 1.000 66.02777  ? 8   HIS A CD2 1 
ATOM   43   C  CE1 . HIS A 1 8   ? 70.32475  -0.59554  -10.93028 1.000 61.63934  ? 8   HIS A CE1 1 
ATOM   44   N  NE2 . HIS A 1 8   ? 69.82474  -1.74792  -10.52198 1.000 66.27920  ? 8   HIS A NE2 1 
ATOM   45   N  N   . ILE A 1 9   ? 72.88037  -1.63126  -14.87933 1.000 58.93582  ? 9   ILE A N   1 
ATOM   46   C  CA  . ILE A 1 9   ? 74.17218  -2.24688  -14.58208 1.000 56.99207  ? 9   ILE A CA  1 
ATOM   47   C  C   . ILE A 1 9   ? 74.84598  -1.42715  -13.48739 1.000 52.28393  ? 9   ILE A C   1 
ATOM   48   O  O   . ILE A 1 9   ? 75.71752  -0.59744  -13.78614 1.000 52.68600  ? 9   ILE A O   1 
ATOM   49   C  CB  . ILE A 1 9   ? 75.06381  -2.33121  -15.83224 1.000 62.71583  ? 9   ILE A CB  1 
ATOM   50   C  CG1 . ILE A 1 9   ? 74.27435  -2.84053  -17.04123 1.000 60.36448  ? 9   ILE A CG1 1 
ATOM   51   C  CG2 . ILE A 1 9   ? 76.26067  -3.23821  -15.56826 1.000 54.60650  ? 9   ILE A CG2 1 
ATOM   52   C  CD1 . ILE A 1 9   ? 73.99279  -4.32995  -17.01847 1.000 59.35327  ? 9   ILE A CD1 1 
ATOM   53   N  N   . PRO A 1 10  ? 74.47904  -1.61381  -12.20610 1.000 51.78779  ? 10  PRO A N   1 
ATOM   54   C  CA  . PRO A 1 10  ? 75.04410  -0.81270  -11.11225 1.000 48.46791  ? 10  PRO A CA  1 
ATOM   55   C  C   . PRO A 1 10  ? 76.45706  -1.22828  -10.69662 1.000 52.50542  ? 10  PRO A C   1 
ATOM   56   O  O   . PRO A 1 10  ? 76.72679  -1.49948  -9.52507  1.000 50.37490  ? 10  PRO A O   1 
ATOM   57   C  CB  . PRO A 1 10  ? 74.03549  -1.02748  -9.98064  1.000 45.64742  ? 10  PRO A CB  1 
ATOM   58   C  CG  . PRO A 1 10  ? 73.48251  -2.38556  -10.23666 1.000 52.80883  ? 10  PRO A CG  1 
ATOM   59   C  CD  . PRO A 1 10  ? 73.42869  -2.53537  -11.73493 1.000 51.60358  ? 10  PRO A CD  1 
ATOM   60   N  N   . LEU A 1 11  ? 77.36455  -1.27540  -11.66511 1.000 46.41010  ? 11  LEU A N   1 
ATOM   61   C  CA  . LEU A 1 11  ? 78.76432  -1.58353  -11.43036 1.000 44.71906  ? 11  LEU A CA  1 
ATOM   62   C  C   . LEU A 1 11  ? 79.62376  -0.49518  -12.05391 1.000 43.75300  ? 11  LEU A C   1 
ATOM   63   O  O   . LEU A 1 11  ? 79.26566  0.05825   -13.09803 1.000 48.22649  ? 11  LEU A O   1 
ATOM   64   C  CB  . LEU A 1 11  ? 79.14088  -2.94850  -12.02647 1.000 49.90550  ? 11  LEU A CB  1 
ATOM   65   C  CG  . LEU A 1 11  ? 78.26194  -4.14112  -11.63928 1.000 49.55875  ? 11  LEU A CG  1 
ATOM   66   C  CD1 . LEU A 1 11  ? 78.65958  -5.37820  -12.43427 1.000 45.79996  ? 11  LEU A CD1 1 
ATOM   67   C  CD2 . LEU A 1 11  ? 78.34398  -4.41466  -10.14584 1.000 41.80201  ? 11  LEU A CD2 1 
ATOM   68   N  N   . PRO A 1 12  ? 80.75900  -0.16436  -11.43911 1.000 45.24683  ? 12  PRO A N   1 
ATOM   69   C  CA  . PRO A 1 12  ? 81.58977  0.92903   -11.96822 1.000 43.95476  ? 12  PRO A CA  1 
ATOM   70   C  C   . PRO A 1 12  ? 82.31418  0.51951   -13.24334 1.000 47.20516  ? 12  PRO A C   1 
ATOM   71   O  O   . PRO A 1 12  ? 82.89908  -0.56288  -13.32194 1.000 46.00399  ? 12  PRO A O   1 
ATOM   72   C  CB  . PRO A 1 12  ? 82.57535  1.20763   -10.82864 1.000 50.29987  ? 12  PRO A CB  1 
ATOM   73   C  CG  . PRO A 1 12  ? 82.67798  -0.09541  -10.10586 1.000 48.13616  ? 12  PRO A CG  1 
ATOM   74   C  CD  . PRO A 1 12  ? 81.31483  -0.73460  -10.19943 1.000 50.90017  ? 12  PRO A CD  1 
ATOM   75   N  N   . GLY A 1 13  ? 82.27934  1.40192   -14.23939 1.000 41.35288  ? 13  GLY A N   1 
ATOM   76   C  CA  . GLY A 1 13  ? 83.03179  1.16337   -15.45812 1.000 40.35184  ? 13  GLY A CA  1 
ATOM   77   C  C   . GLY A 1 13  ? 84.52431  1.33349   -15.22704 1.000 43.78011  ? 13  GLY A C   1 
ATOM   78   O  O   . GLY A 1 13  ? 84.97189  2.26951   -14.56292 1.000 40.60915  ? 13  GLY A O   1 
ATOM   79   N  N   . ARG A 1 14  ? 85.30248  0.40678   -15.78198 1.000 37.85267  ? 14  ARG A N   1 
ATOM   80   C  CA  . ARG A 1 14  ? 86.74779  0.40940   -15.61654 1.000 36.19230  ? 14  ARG A CA  1 
ATOM   81   C  C   . ARG A 1 14  ? 87.41029  0.06834   -16.94291 1.000 39.74872  ? 14  ARG A C   1 
ATOM   82   O  O   . ARG A 1 14  ? 86.85833  -0.67563  -17.75760 1.000 39.99967  ? 14  ARG A O   1 
ATOM   83   C  CB  . ARG A 1 14  ? 87.19863  -0.59005  -14.53787 1.000 34.78380  ? 14  ARG A CB  1 
ATOM   84   C  CG  . ARG A 1 14  ? 86.62701  -0.32010  -13.14542 1.000 37.70340  ? 14  ARG A CG  1 
ATOM   85   C  CD  . ARG A 1 14  ? 86.77817  -1.53335  -12.24789 1.000 33.52424  ? 14  ARG A CD  1 
ATOM   86   N  NE  . ARG A 1 14  ? 88.17442  -1.91015  -12.06787 1.000 34.30128  ? 14  ARG A NE  1 
ATOM   87   C  CZ  . ARG A 1 14  ? 88.57329  -3.06785  -11.55809 1.000 38.17253  ? 14  ARG A CZ  1 
ATOM   88   N  NH1 . ARG A 1 14  ? 87.70593  -4.00237  -11.20337 1.000 34.02619  ? 14  ARG A NH1 1 
ATOM   89   N  NH2 . ARG A 1 14  ? 89.87444  -3.29660  -11.40649 1.000 30.87985  ? 14  ARG A NH2 1 
ATOM   90   N  N   . GLN A 1 15  ? 88.60376  0.62063   -17.14973 1.000 33.28843  ? 15  GLN A N   1 
ATOM   91   C  CA  . GLN A 1 15  ? 89.39059  0.33924   -18.34264 1.000 38.07207  ? 15  GLN A CA  1 
ATOM   92   C  C   . GLN A 1 15  ? 90.86108  0.36217   -17.96104 1.000 36.28965  ? 15  GLN A C   1 
ATOM   93   O  O   . GLN A 1 15  ? 91.29602  1.25860   -17.23352 1.000 39.34471  ? 15  GLN A O   1 
ATOM   94   C  CB  . GLN A 1 15  ? 89.10722  1.35538   -19.45926 1.000 35.18528  ? 15  GLN A CB  1 
ATOM   95   C  CG  . GLN A 1 15  ? 90.03094  1.21476   -20.66065 1.000 37.60019  ? 15  GLN A CG  1 
ATOM   96   C  CD  . GLN A 1 15  ? 89.60567  2.06728   -21.84148 1.000 43.76648  ? 15  GLN A CD  1 
ATOM   97   O  OE1 . GLN A 1 15  ? 89.49555  3.28865   -21.73589 1.000 45.12878  ? 15  GLN A OE1 1 
ATOM   98   N  NE2 . GLN A 1 15  ? 89.36331  1.42294   -22.97601 1.000 38.88885  ? 15  GLN A NE2 1 
ATOM   99   N  N   . SER A 1 16  ? 91.61510  -0.61536  -18.45559 1.000 35.29959  ? 16  SER A N   1 
ATOM   100  C  CA  . SER A 1 16  ? 93.02307  -0.72025  -18.10409 1.000 33.24278  ? 16  SER A CA  1 
ATOM   101  C  C   . SER A 1 16  ? 93.76379  0.56318   -18.46951 1.000 40.22803  ? 16  SER A C   1 
ATOM   102  O  O   . SER A 1 16  ? 93.49678  1.15638   -19.51951 1.000 39.72115  ? 16  SER A O   1 
ATOM   103  C  CB  . SER A 1 16  ? 93.67006  -1.90499  -18.81685 1.000 38.64031  ? 16  SER A CB  1 
ATOM   104  O  OG  . SER A 1 16  ? 95.08263  -1.80051  -18.75486 1.000 34.63063  ? 16  SER A OG  1 
ATOM   105  N  N   . PRO A 1 17  ? 94.69936  1.01845   -17.63125 1.000 44.61804  ? 17  PRO A N   1 
ATOM   106  C  CA  . PRO A 1 17  ? 95.46914  2.22369   -17.97940 1.000 45.77484  ? 17  PRO A CA  1 
ATOM   107  C  C   . PRO A 1 17  ? 96.42402  2.02102   -19.14301 1.000 48.31097  ? 17  PRO A C   1 
ATOM   108  O  O   . PRO A 1 17  ? 96.90225  3.01355   -19.70629 1.000 45.60493  ? 17  PRO A O   1 
ATOM   109  C  CB  . PRO A 1 17  ? 96.22974  2.54212   -16.68627 1.000 45.67221  ? 17  PRO A CB  1 
ATOM   110  C  CG  . PRO A 1 17  ? 96.32915  1.21840   -15.97375 1.000 50.74762  ? 17  PRO A CG  1 
ATOM   111  C  CD  . PRO A 1 17  ? 95.06260  0.47981   -16.30767 1.000 36.21004  ? 17  PRO A CD  1 
ATOM   112  N  N   . ASP A 1 18  ? 96.72290  0.77669   -19.51819 1.000 45.55944  ? 18  ASP A N   1 
ATOM   113  C  CA  . ASP A 1 18  ? 97.59672  0.48123   -20.64523 1.000 40.86326  ? 18  ASP A CA  1 
ATOM   114  C  C   . ASP A 1 18  ? 96.81393  0.22206   -21.92721 1.000 42.05698  ? 18  ASP A C   1 
ATOM   115  O  O   . ASP A 1 18  ? 97.33036  -0.43015  -22.83988 1.000 39.54790  ? 18  ASP A O   1 
ATOM   116  C  CB  . ASP A 1 18  ? 98.48661  -0.71785  -20.31725 1.000 40.14338  ? 18  ASP A CB  1 
ATOM   117  C  CG  . ASP A 1 18  ? 99.79540  -0.69991  -21.07798 1.000 44.86910  ? 18  ASP A CG  1 
ATOM   118  O  OD1 . ASP A 1 18  ? 100.14748 0.35913   -21.64012 1.000 52.25415  ? 18  ASP A OD1 1 
ATOM   119  O  OD2 . ASP A 1 18  ? 100.47587 -1.74641  -21.11073 1.000 45.45833  ? 18  ASP A OD2 1 
ATOM   120  N  N   . HIS A 1 19  ? 95.57920  0.72489   -22.01176 1.000 42.75755  ? 19  HIS A N   1 
ATOM   121  C  CA  . HIS A 1 19  ? 94.70541  0.39177   -23.13341 1.000 39.74072  ? 19  HIS A CA  1 
ATOM   122  C  C   . HIS A 1 19  ? 95.21734  0.97847   -24.44482 1.000 49.07286  ? 19  HIS A C   1 
ATOM   123  O  O   . HIS A 1 19  ? 95.09552  0.34513   -25.50127 1.000 42.59548  ? 19  HIS A O   1 
ATOM   124  C  CB  . HIS A 1 19  ? 93.28682  0.88736   -22.85006 1.000 38.15017  ? 19  HIS A CB  1 
ATOM   125  C  CG  . HIS A 1 19  ? 93.14075  2.37451   -22.94284 1.000 51.46878  ? 19  HIS A CG  1 
ATOM   126  N  ND1 . HIS A 1 19  ? 93.49415  3.22406   -21.91623 1.000 49.69349  ? 19  HIS A ND1 1 
ATOM   127  C  CD2 . HIS A 1 19  ? 92.69726  3.16530   -23.94868 1.000 49.33418  ? 19  HIS A CD2 1 
ATOM   128  C  CE1 . HIS A 1 19  ? 93.26597  4.47291   -22.28205 1.000 54.26259  ? 19  HIS A CE1 1 
ATOM   129  N  NE2 . HIS A 1 19  ? 92.78215  4.46514   -23.51123 1.000 56.25163  ? 19  HIS A NE2 1 
ATOM   130  N  N   . ALA A 1 20  ? 95.78249  2.18916   -24.40179 1.000 45.10981  ? 20  ALA A N   1 
ATOM   131  C  CA  . ALA A 1 20  ? 96.18233  2.85833   -25.63658 1.000 51.46195  ? 20  ALA A CA  1 
ATOM   132  C  C   . ALA A 1 20  ? 97.30065  2.10057   -26.33934 1.000 46.22562  ? 20  ALA A C   1 
ATOM   133  O  O   . ALA A 1 20  ? 97.27398  1.94197   -27.56596 1.000 44.61535  ? 20  ALA A O   1 
ATOM   134  C  CB  . ALA A 1 20  ? 96.60482  4.29705   -25.34467 1.000 44.13221  ? 20  ALA A CB  1 
ATOM   135  N  N   . ARG A 1 21  ? 98.29070  1.62240   -25.58101 1.000 45.34954  ? 21  ARG A N   1 
ATOM   136  C  CA  . ARG A 1 21  ? 99.34506  0.81727   -26.18586 1.000 43.10332  ? 21  ARG A CA  1 
ATOM   137  C  C   . ARG A 1 21  ? 98.79503  -0.50396  -26.71073 1.000 49.00886  ? 21  ARG A C   1 
ATOM   138  O  O   . ARG A 1 21  ? 99.14186  -0.93206  -27.81788 1.000 49.89364  ? 21  ARG A O   1 
ATOM   139  C  CB  . ARG A 1 21  ? 100.46343 0.56428   -25.17833 1.000 39.70745  ? 21  ARG A CB  1 
ATOM   140  C  CG  . ARG A 1 21  ? 101.58995 -0.28985  -25.73633 1.000 43.35634  ? 21  ARG A CG  1 
ATOM   141  C  CD  . ARG A 1 21  ? 102.29108 -1.09126  -24.64910 1.000 47.17210  ? 21  ARG A CD  1 
ATOM   142  N  NE  . ARG A 1 21  ? 101.36205 -1.91895  -23.88740 1.000 45.41393  ? 21  ARG A NE  1 
ATOM   143  C  CZ  . ARG A 1 21  ? 100.86195 -3.07519  -24.30572 1.000 49.08090  ? 21  ARG A CZ  1 
ATOM   144  N  NH1 . ARG A 1 21  ? 101.16053 -3.57153  -25.49597 1.000 42.28482  ? 21  ARG A NH1 1 
ATOM   145  N  NH2 . ARG A 1 21  ? 100.03538 -3.74924  -23.51190 1.000 38.54426  ? 21  ARG A NH2 1 
ATOM   146  N  N   . ALA A 1 22  ? 97.93607  -1.16517  -25.92815 1.000 42.33191  ? 22  ALA A N   1 
ATOM   147  C  CA  . ALA A 1 22  ? 97.38517  -2.44907  -26.35188 1.000 46.28430  ? 22  ALA A CA  1 
ATOM   148  C  C   . ALA A 1 22  ? 96.56591  -2.30123  -27.62447 1.000 44.32672  ? 22  ALA A C   1 
ATOM   149  O  O   . ALA A 1 22  ? 96.63571  -3.15033  -28.52235 1.000 42.05496  ? 22  ALA A O   1 
ATOM   150  C  CB  . ALA A 1 22  ? 96.52915  -3.04964  -25.23867 1.000 38.86565  ? 22  ALA A CB  1 
ATOM   151  N  N   . GLU A 1 23  ? 95.77612  -1.23067  -27.71419 1.000 39.74718  ? 23  GLU A N   1 
ATOM   152  C  CA  . GLU A 1 23  ? 95.00932  -0.97275  -28.92648 1.000 45.37328  ? 23  GLU A CA  1 
ATOM   153  C  C   . GLU A 1 23  ? 95.92723  -0.64981  -30.09966 1.000 49.78422  ? 23  GLU A C   1 
ATOM   154  O  O   . GLU A 1 23  ? 95.65222  -1.04607  -31.23789 1.000 47.76335  ? 23  GLU A O   1 
ATOM   155  C  CB  . GLU A 1 23  ? 94.01877  0.16304   -28.67543 1.000 49.51412  ? 23  GLU A CB  1 
ATOM   156  C  CG  . GLU A 1 23  ? 93.30314  0.68182   -29.91420 1.000 52.99012  ? 23  GLU A CG  1 
ATOM   157  C  CD  . GLU A 1 23  ? 92.10656  1.54459   -29.56060 1.000 67.86701  ? 23  GLU A CD  1 
ATOM   158  O  OE1 . GLU A 1 23  ? 91.25656  1.07528   -28.77367 1.000 74.42108  ? 23  GLU A OE1 1 
ATOM   159  O  OE2 . GLU A 1 23  ? 92.01948  2.69160   -30.05185 1.000 66.03251  ? 23  GLU A OE2 1 
ATOM   160  N  N   . ALA A 1 24  ? 97.03571  0.04601   -29.83647 1.000 43.08596  ? 24  ALA A N   1 
ATOM   161  C  CA  . ALA A 1 24  ? 97.95270  0.41874   -30.90787 1.000 48.31908  ? 24  ALA A CA  1 
ATOM   162  C  C   . ALA A 1 24  ? 98.68702  -0.78882  -31.47804 1.000 48.63647  ? 24  ALA A C   1 
ATOM   163  O  O   . ALA A 1 24  ? 98.98571  -0.81812  -32.67676 1.000 43.16739  ? 24  ALA A O   1 
ATOM   164  C  CB  . ALA A 1 24  ? 98.95881  1.45423   -30.40205 1.000 41.83412  ? 24  ALA A CB  1 
ATOM   165  N  N   . GLU A 1 25  ? 98.98372  -1.78816  -30.64854 1.000 43.80758  ? 25  GLU A N   1 
ATOM   166  C  CA  . GLU A 1 25  ? 99.80458  -2.92129  -31.05329 1.000 44.94007  ? 25  GLU A CA  1 
ATOM   167  C  C   . GLU A 1 25  ? 98.99001  -4.17430  -31.35574 1.000 37.11656  ? 25  GLU A C   1 
ATOM   168  O  O   . GLU A 1 25  ? 99.57635  -5.23309  -31.60284 1.000 41.40879  ? 25  GLU A O   1 
ATOM   169  C  CB  . GLU A 1 25  ? 100.84280 -3.22371  -29.96858 1.000 41.57612  ? 25  GLU A CB  1 
ATOM   170  C  CG  . GLU A 1 25  ? 101.84146 -2.09442  -29.73386 1.000 44.05580  ? 25  GLU A CG  1 
ATOM   171  C  CD  . GLU A 1 25  ? 102.79637 -2.37772  -28.58770 1.000 56.20508  ? 25  GLU A CD  1 
ATOM   172  O  OE1 . GLU A 1 25  ? 102.51110 -3.28575  -27.77800 1.000 59.61187  ? 25  GLU A OE1 1 
ATOM   173  O  OE2 . GLU A 1 25  ? 103.83477 -1.68973  -28.49553 1.000 59.39250  ? 25  GLU A OE2 1 
ATOM   174  N  N   . GLN A 1 26  ? 97.65819  -4.07160  -31.37096 1.000 35.37493  ? 26  GLN A N   1 
ATOM   175  C  CA  . GLN A 1 26  ? 96.80788  -5.25839  -31.37203 1.000 36.50747  ? 26  GLN A CA  1 
ATOM   176  C  C   . GLN A 1 26  ? 96.94960  -6.10218  -32.63416 1.000 42.69972  ? 26  GLN A C   1 
ATOM   177  O  O   . GLN A 1 26  ? 96.67629  -7.30554  -32.58376 1.000 39.32106  ? 26  GLN A O   1 
ATOM   178  C  CB  . GLN A 1 26  ? 95.34136  -4.85836  -31.19936 1.000 37.01046  ? 26  GLN A CB  1 
ATOM   179  C  CG  . GLN A 1 26  ? 94.74461  -4.18031  -32.42100 1.000 38.94857  ? 26  GLN A CG  1 
ATOM   180  C  CD  . GLN A 1 26  ? 93.32057  -3.72281  -32.20504 1.000 38.98268  ? 26  GLN A CD  1 
ATOM   181  O  OE1 . GLN A 1 26  ? 92.37387  -4.49504  -32.36649 1.000 40.92120  ? 26  GLN A OE1 1 
ATOM   182  N  NE2 . GLN A 1 26  ? 93.15778  -2.45429  -31.84623 1.000 41.98269  ? 26  GLN A NE2 1 
ATOM   183  N  N   . LEU A 1 27  ? 97.36111  -5.50920  -33.76054 1.000 38.97552  ? 27  LEU A N   1 
ATOM   184  C  CA  . LEU A 1 27  ? 97.38642  -6.23609  -35.02597 1.000 38.68266  ? 27  LEU A CA  1 
ATOM   185  C  C   . LEU A 1 27  ? 98.61356  -7.12052  -35.18142 1.000 40.25313  ? 27  LEU A C   1 
ATOM   186  O  O   . LEU A 1 27  ? 98.58248  -8.05544  -35.98753 1.000 43.57682  ? 27  LEU A O   1 
ATOM   187  C  CB  . LEU A 1 27  ? 97.32299  -5.26256  -36.20737 1.000 34.20761  ? 27  LEU A CB  1 
ATOM   188  C  CG  . LEU A 1 27  ? 96.02439  -4.47852  -36.41750 1.000 43.45410  ? 27  LEU A CG  1 
ATOM   189  C  CD1 . LEU A 1 27  ? 96.18904  -3.48656  -37.55142 1.000 38.45749  ? 27  LEU A CD1 1 
ATOM   190  C  CD2 . LEU A 1 27  ? 94.84174  -5.40007  -36.69049 1.000 35.48251  ? 27  LEU A CD2 1 
ATOM   191  N  N   . ALA A 1 28  ? 99.68360  -6.85227  -34.43005 1.000 39.80616  ? 28  ALA A N   1 
ATOM   192  C  CA  . ALA A 1 28  ? 100.94062 -7.56198  -34.64577 1.000 43.34932  ? 28  ALA A CA  1 
ATOM   193  C  C   . ALA A 1 28  ? 100.78756 -9.06327  -34.42861 1.000 44.43984  ? 28  ALA A C   1 
ATOM   194  O  O   . ALA A 1 28  ? 101.33483 -9.86556  -35.19554 1.000 42.31181  ? 28  ALA A O   1 
ATOM   195  C  CB  . ALA A 1 28  ? 102.02682 -6.99293  -33.73244 1.000 36.34163  ? 28  ALA A CB  1 
ATOM   196  N  N   . TRP A 1 29  ? 100.03847 -9.46729  -33.39642 1.000 40.78336  ? 29  TRP A N   1 
ATOM   197  C  CA  . TRP A 1 29  ? 99.94371  -10.89560 -33.09472 1.000 38.81089  ? 29  TRP A CA  1 
ATOM   198  C  C   . TRP A 1 29  ? 99.09905  -11.65697 -34.11086 1.000 38.67906  ? 29  TRP A C   1 
ATOM   199  O  O   . TRP A 1 29  ? 99.57685  -12.68142 -34.62864 1.000 40.53236  ? 29  TRP A O   1 
ATOM   200  C  CB  . TRP A 1 29  ? 99.43226  -11.10609 -31.66588 1.000 36.48828  ? 29  TRP A CB  1 
ATOM   201  C  CG  . TRP A 1 29  ? 99.22846  -12.55402 -31.35529 1.000 38.29964  ? 29  TRP A CG  1 
ATOM   202  C  CD1 . TRP A 1 29  ? 100.18024 -13.45007 -30.96073 1.000 36.99523  ? 29  TRP A CD1 1 
ATOM   203  C  CD2 . TRP A 1 29  ? 97.99987  -13.28531 -31.44169 1.000 34.73143  ? 29  TRP A CD2 1 
ATOM   204  N  NE1 . TRP A 1 29  ? 99.61693  -14.69144 -30.78585 1.000 38.19066  ? 29  TRP A NE1 1 
ATOM   205  C  CE2 . TRP A 1 29  ? 98.27860  -14.61576 -31.07145 1.000 37.09631  ? 29  TRP A CE2 1 
ATOM   206  C  CE3 . TRP A 1 29  ? 96.69092  -12.94227 -31.78554 1.000 35.51786  ? 29  TRP A CE3 1 
ATOM   207  C  CZ2 . TRP A 1 29  ? 97.29682  -15.60310 -31.04092 1.000 33.55232  ? 29  TRP A CZ2 1 
ATOM   208  C  CZ3 . TRP A 1 29  ? 95.71651  -13.92420 -31.75351 1.000 37.48326  ? 29  TRP A CZ3 1 
ATOM   209  C  CH2 . TRP A 1 29  ? 96.02485  -15.23847 -31.38524 1.000 32.91603  ? 29  TRP A CH2 1 
ATOM   210  N  N   . PRO A 1 30  ? 97.86320  -11.25316 -34.43169 1.000 37.81757  ? 30  PRO A N   1 
ATOM   211  C  CA  . PRO A 1 30  ? 97.11709  -12.00549 -35.45681 1.000 40.09657  ? 30  PRO A CA  1 
ATOM   212  C  C   . PRO A 1 30  ? 97.76595  -11.95513 -36.83120 1.000 45.10969  ? 30  PRO A C   1 
ATOM   213  O  O   . PRO A 1 30  ? 97.56908  -12.87754 -37.63193 1.000 46.20027  ? 30  PRO A O   1 
ATOM   214  C  CB  . PRO A 1 30  ? 95.73438  -11.33779 -35.45245 1.000 38.53925  ? 30  PRO A CB  1 
ATOM   215  C  CG  . PRO A 1 30  ? 95.96360  -9.98467  -34.87899 1.000 45.98480  ? 30  PRO A CG  1 
ATOM   216  C  CD  . PRO A 1 30  ? 97.05651  -10.15406 -33.87046 1.000 36.77826  ? 30  PRO A CD  1 
ATOM   217  N  N   . ARG A 1 31  ? 98.53988  -10.90915 -37.12788 1.000 43.83577  ? 31  ARG A N   1 
ATOM   218  C  CA  . ARG A 1 31  ? 99.29584  -10.87741 -38.37658 1.000 44.40184  ? 31  ARG A CA  1 
ATOM   219  C  C   . ARG A 1 31  ? 100.37650 -11.95116 -38.38847 1.000 47.57060  ? 31  ARG A C   1 
ATOM   220  O  O   . ARG A 1 31  ? 100.52360 -12.68718 -39.37142 1.000 46.09373  ? 31  ARG A O   1 
ATOM   221  C  CB  . ARG A 1 31  ? 99.92196  -9.49780  -38.58206 1.000 45.99934  ? 31  ARG A CB  1 
ATOM   222  C  CG  . ARG A 1 31  ? 98.96982  -8.42585  -39.07848 1.000 49.92440  ? 31  ARG A CG  1 
ATOM   223  C  CD  . ARG A 1 31  ? 98.87457  -8.43946  -40.59503 1.000 61.16277  ? 31  ARG A CD  1 
ATOM   224  N  NE  . ARG A 1 31  ? 98.33385  -7.18850  -41.11194 1.000 59.37712  ? 31  ARG A NE  1 
ATOM   225  C  CZ  . ARG A 1 31  ? 98.11636  -6.93662  -42.39597 1.000 58.73303  ? 31  ARG A CZ  1 
ATOM   226  N  NH1 . ARG A 1 31  ? 98.37020  -7.83705  -43.33171 1.000 53.15126  ? 31  ARG A NH1 1 
ATOM   227  N  NH2 . ARG A 1 31  ? 97.63260  -5.74998  -42.75008 1.000 50.11770  ? 31  ARG A NH2 1 
ATOM   228  N  N   . SER A 1 32  ? 101.15234 -12.04894 -37.30383 1.000 40.45806  ? 32  SER A N   1 
ATOM   229  C  CA  . SER A 1 32  ? 102.23025 -13.03096 -37.24793 1.000 45.31448  ? 32  SER A CA  1 
ATOM   230  C  C   . SER A 1 32  ? 101.71037 -14.46187 -37.25136 1.000 41.61854  ? 32  SER A C   1 
ATOM   231  O  O   . SER A 1 32  ? 102.44411 -15.37327 -37.64879 1.000 48.43936  ? 32  SER A O   1 
ATOM   232  C  CB  . SER A 1 32  ? 103.09660 -12.80223 -36.00885 1.000 42.51725  ? 32  SER A CB  1 
ATOM   233  O  OG  . SER A 1 32  ? 102.43868 -13.26212 -34.84070 1.000 51.77876  ? 32  SER A OG  1 
ATOM   234  N  N   . LEU A 1 33  ? 100.47218 -14.67917 -36.81435 1.000 41.57099  ? 33  LEU A N   1 
ATOM   235  C  CA  . LEU A 1 33  ? 99.85583  -15.99867 -36.81376 1.000 44.31553  ? 33  LEU A CA  1 
ATOM   236  C  C   . LEU A 1 33  ? 99.07701  -16.28237 -38.09468 1.000 45.37503  ? 33  LEU A C   1 
ATOM   237  O  O   . LEU A 1 33  ? 98.44778  -17.34023 -38.20218 1.000 45.34390  ? 33  LEU A O   1 
ATOM   238  C  CB  . LEU A 1 33  ? 98.93333  -16.15182 -35.59848 1.000 38.31684  ? 33  LEU A CB  1 
ATOM   239  C  CG  . LEU A 1 33  ? 99.50593  -16.68405 -34.27672 1.000 44.59330  ? 33  LEU A CG  1 
ATOM   240  C  CD1 . LEU A 1 33  ? 99.82100  -18.16337 -34.39077 1.000 45.82800  ? 33  LEU A CD1 1 
ATOM   241  C  CD2 . LEU A 1 33  ? 100.74577 -15.92116 -33.84949 1.000 44.08934  ? 33  LEU A CD2 1 
ATOM   242  N  N   . GLY A 1 34  ? 99.10420  -15.36804 -39.06310 1.000 43.14794  ? 34  GLY A N   1 
ATOM   243  C  CA  . GLY A 1 34  ? 98.37735  -15.57545 -40.29974 1.000 37.50032  ? 34  GLY A CA  1 
ATOM   244  C  C   . GLY A 1 34  ? 96.87460  -15.51119 -40.17254 1.000 40.64598  ? 34  GLY A C   1 
ATOM   245  O  O   . GLY A 1 34  ? 96.16861  -16.06732 -41.01664 1.000 40.13471  ? 34  GLY A O   1 
ATOM   246  N  N   . LEU A 1 35  ? 96.35984  -14.84801 -39.13570 1.000 38.21240  ? 35  LEU A N   1 
ATOM   247  C  CA  . LEU A 1 35  ? 94.92129  -14.71928 -38.94745 1.000 38.77135  ? 35  LEU A CA  1 
ATOM   248  C  C   . LEU A 1 35  ? 94.34527  -13.48217 -39.62129 1.000 36.84335  ? 35  LEU A C   1 
ATOM   249  O  O   . LEU A 1 35  ? 93.15408  -13.46853 -39.94996 1.000 39.55318  ? 35  LEU A O   1 
ATOM   250  C  CB  . LEU A 1 35  ? 94.58448  -14.68747 -37.45348 1.000 39.07724  ? 35  LEU A CB  1 
ATOM   251  C  CG  . LEU A 1 35  ? 95.11135  -15.85410 -36.61756 1.000 43.32838  ? 35  LEU A CG  1 
ATOM   252  C  CD1 . LEU A 1 35  ? 94.73802  -15.68049 -35.14444 1.000 34.60365  ? 35  LEU A CD1 1 
ATOM   253  C  CD2 . LEU A 1 35  ? 94.57769  -17.16591 -37.16994 1.000 38.52282  ? 35  LEU A CD2 1 
ATOM   254  N  N   . ILE A 1 36  ? 95.15373  -12.44483 -39.81420 1.000 41.83374  ? 36  ILE A N   1 
ATOM   255  C  CA  . ILE A 1 36  ? 94.77721  -11.26161 -40.57917 1.000 44.21399  ? 36  ILE A CA  1 
ATOM   256  C  C   . ILE A 1 36  ? 95.74535  -11.16412 -41.74673 1.000 44.34894  ? 36  ILE A C   1 
ATOM   257  O  O   . ILE A 1 36  ? 96.95288  -10.98819 -41.54243 1.000 47.85714  ? 36  ILE A O   1 
ATOM   258  C  CB  . ILE A 1 36  ? 94.80974  -9.98605  -39.72290 1.000 49.31286  ? 36  ILE A CB  1 
ATOM   259  C  CG1 . ILE A 1 36  ? 93.69395  -10.02428 -38.67717 1.000 41.06798  ? 36  ILE A CG1 1 
ATOM   260  C  CG2 . ILE A 1 36  ? 94.69129  -8.75044  -40.60279 1.000 44.04740  ? 36  ILE A CG2 1 
ATOM   261  C  CD1 . ILE A 1 36  ? 93.68775  -8.83550  -37.75673 1.000 51.75485  ? 36  ILE A CD1 1 
ATOM   262  N  N   . ARG A 1 37  ? 95.22315  -11.28806 -42.96715 1.000 37.51230  ? 37  ARG A N   1 
ATOM   263  C  CA  . ARG A 1 37  ? 96.06701  -11.48658 -44.14021 1.000 52.33191  ? 37  ARG A CA  1 
ATOM   264  C  C   . ARG A 1 37  ? 95.91660  -10.39127 -45.19014 1.000 46.81929  ? 37  ARG A C   1 
ATOM   265  O  O   . ARG A 1 37  ? 96.45343  -10.53518 -46.29483 1.000 53.07382  ? 37  ARG A O   1 
ATOM   266  C  CB  . ARG A 1 37  ? 95.77655  -12.85850 -44.75861 1.000 52.60792  ? 37  ARG A CB  1 
ATOM   267  C  CG  . ARG A 1 37  ? 95.86324  -14.00012 -43.74807 1.000 54.67727  ? 37  ARG A CG  1 
ATOM   268  C  CD  . ARG A 1 37  ? 95.41406  -15.32717 -44.33063 1.000 55.17529  ? 37  ARG A CD  1 
ATOM   269  N  NE  . ARG A 1 37  ? 96.45666  -15.95701 -45.13017 1.000 60.32916  ? 37  ARG A NE  1 
ATOM   270  C  CZ  . ARG A 1 37  ? 97.22633  -16.95189 -44.70940 1.000 68.07945  ? 37  ARG A CZ  1 
ATOM   271  N  NH1 . ARG A 1 37  ? 97.09899  -17.46126 -43.49414 1.000 53.78552  ? 37  ARG A NH1 1 
ATOM   272  N  NH2 . ARG A 1 37  ? 98.14416  -17.45245 -45.53017 1.000 65.17743  ? 37  ARG A NH2 1 
ATOM   273  N  N   . SER A 1 38  ? 95.21025  -9.30488  -44.88146 1.000 46.98426  ? 38  SER A N   1 
ATOM   274  C  CA  . SER A 1 38  ? 95.08696  -8.18184  -45.80034 1.000 46.29197  ? 38  SER A CA  1 
ATOM   275  C  C   . SER A 1 38  ? 94.82357  -6.91795  -44.99493 1.000 50.86371  ? 38  SER A C   1 
ATOM   276  O  O   . SER A 1 38  ? 94.47914  -6.96994  -43.81103 1.000 43.45212  ? 38  SER A O   1 
ATOM   277  C  CB  . SER A 1 38  ? 93.97452  -8.40898  -46.82968 1.000 38.46872  ? 38  SER A CB  1 
ATOM   278  O  OG  . SER A 1 38  ? 92.69545  -8.34756  -46.22244 1.000 39.91368  ? 38  SER A OG  1 
ATOM   279  N  N   . ASP A 1 39  ? 94.98714  -5.76992  -45.65731 1.000 43.91407  ? 39  ASP A N   1 
ATOM   280  C  CA  . ASP A 1 39  ? 94.76286  -4.49757  -44.98166 1.000 43.89549  ? 39  ASP A CA  1 
ATOM   281  C  C   . ASP A 1 39  ? 93.27973  -4.23177  -44.76696 1.000 37.35086  ? 39  ASP A C   1 
ATOM   282  O  O   . ASP A 1 39  ? 92.90853  -3.55257  -43.80395 1.000 44.50360  ? 39  ASP A O   1 
ATOM   283  C  CB  . ASP A 1 39  ? 95.40884  -3.36092  -45.77372 1.000 45.24452  ? 39  ASP A CB  1 
ATOM   284  C  CG  . ASP A 1 39  ? 96.91776  -3.49525  -45.85355 1.000 48.15506  ? 39  ASP A CG  1 
ATOM   285  O  OD1 . ASP A 1 39  ? 97.49198  -4.22394  -45.01769 1.000 48.90138  ? 39  ASP A OD1 1 
ATOM   286  O  OD2 . ASP A 1 39  ? 97.53112  -2.87187  -46.74570 1.000 49.81248  ? 39  ASP A OD2 1 
ATOM   287  N  N   . ALA A 1 40  ? 92.41887  -4.75387  -45.64322 1.000 35.30219  ? 40  ALA A N   1 
ATOM   288  C  CA  . ALA A 1 40  ? 90.98381  -4.61655  -45.42161 1.000 37.36617  ? 40  ALA A CA  1 
ATOM   289  C  C   . ALA A 1 40  ? 90.52752  -5.47668  -44.25013 1.000 40.49697  ? 40  ALA A C   1 
ATOM   290  O  O   . ALA A 1 40  ? 89.63330  -5.08216  -43.49283 1.000 37.60745  ? 40  ALA A O   1 
ATOM   291  C  CB  . ALA A 1 40  ? 90.21304  -4.98476  -46.68835 1.000 32.88993  ? 40  ALA A CB  1 
ATOM   292  N  N   . ALA A 1 41  ? 91.11393  -6.66636  -44.10082 1.000 40.74638  ? 41  ALA A N   1 
ATOM   293  C  CA  . ALA A 1 41  ? 90.82450  -7.48892  -42.93281 1.000 42.35098  ? 41  ALA A CA  1 
ATOM   294  C  C   . ALA A 1 41  ? 91.33428  -6.82314  -41.66208 1.000 37.66910  ? 41  ALA A C   1 
ATOM   295  O  O   . ALA A 1 41  ? 90.68476  -6.89712  -40.61364 1.000 37.20800  ? 41  ALA A O   1 
ATOM   296  C  CB  . ALA A 1 41  ? 91.43961  -8.87861  -43.10042 1.000 37.40327  ? 41  ALA A CB  1 
ATOM   297  N  N   . ALA A 1 42  ? 92.48617  -6.15143  -41.74393 1.000 38.40250  ? 42  ALA A N   1 
ATOM   298  C  CA  . ALA A 1 42  ? 93.02704  -5.45878  -40.57921 1.000 37.65792  ? 42  ALA A CA  1 
ATOM   299  C  C   . ALA A 1 42  ? 92.11422  -4.32407  -40.13520 1.000 41.66891  ? 42  ALA A C   1 
ATOM   300  O  O   . ALA A 1 42  ? 91.88212  -4.13798  -38.93355 1.000 39.71875  ? 42  ALA A O   1 
ATOM   301  C  CB  . ALA A 1 42  ? 94.42652  -4.93089  -40.88679 1.000 35.57120  ? 42  ALA A CB  1 
ATOM   302  N  N   . GLU A 1 43  ? 91.58149  -3.55661  -41.09064 1.000 35.58708  ? 43  GLU A N   1 
ATOM   303  C  CA  . GLU A 1 43  ? 90.70007  -2.44858  -40.73483 1.000 39.08744  ? 43  GLU A CA  1 
ATOM   304  C  C   . GLU A 1 43  ? 89.37136  -2.95304  -40.18584 1.000 35.47563  ? 43  GLU A C   1 
ATOM   305  O  O   . GLU A 1 43  ? 88.81810  -2.36443  -39.25040 1.000 36.44341  ? 43  GLU A O   1 
ATOM   306  C  CB  . GLU A 1 43  ? 90.47776  -1.53735  -41.94395 1.000 32.46600  ? 43  GLU A CB  1 
ATOM   307  C  CG  . GLU A 1 43  ? 89.35773  -0.51204  -41.76906 1.000 35.14375  ? 43  GLU A CG  1 
ATOM   308  C  CD  . GLU A 1 43  ? 89.65204  0.53870   -40.69685 1.000 39.00008  ? 43  GLU A CD  1 
ATOM   309  O  OE1 . GLU A 1 43  ? 90.82132  0.67813   -40.27889 1.000 36.89826  ? 43  GLU A OE1 1 
ATOM   310  O  OE2 . GLU A 1 43  ? 88.70379  1.23600   -40.27605 1.000 42.04493  ? 43  GLU A OE2 1 
ATOM   311  N  N   . ARG A 1 44  ? 88.84102  -4.03944  -40.75274 1.000 35.48460  ? 44  ARG A N   1 
ATOM   312  C  CA  . ARG A 1 44  ? 87.63465  -4.64293  -40.19352 1.000 37.28280  ? 44  ARG A CA  1 
ATOM   313  C  C   . ARG A 1 44  ? 87.87575  -5.12458  -38.76972 1.000 36.85415  ? 44  ARG A C   1 
ATOM   314  O  O   . ARG A 1 44  ? 86.97184  -5.08014  -37.92790 1.000 36.75002  ? 44  ARG A O   1 
ATOM   315  C  CB  . ARG A 1 44  ? 87.15958  -5.80020  -41.07402 1.000 45.13966  ? 44  ARG A CB  1 
ATOM   316  C  CG  . ARG A 1 44  ? 85.94566  -5.46813  -41.92632 1.000 62.22215  ? 44  ARG A CG  1 
ATOM   317  C  CD  . ARG A 1 44  ? 85.49246  -6.66257  -42.74919 1.000 64.78002  ? 44  ARG A CD  1 
ATOM   318  N  NE  . ARG A 1 44  ? 86.45664  -7.00320  -43.78799 1.000 70.34582  ? 44  ARG A NE  1 
ATOM   319  C  CZ  . ARG A 1 44  ? 86.32353  -6.69530  -45.07158 1.000 61.30332  ? 44  ARG A CZ  1 
ATOM   320  N  NH1 . ARG A 1 44  ? 85.25844  -6.05266  -45.52393 1.000 61.55616  ? 44  ARG A NH1 1 
ATOM   321  N  NH2 . ARG A 1 44  ? 87.28256  -7.04426  -45.92382 1.000 60.20007  ? 44  ARG A NH2 1 
ATOM   322  N  N   . HIS A 1 45  ? 89.08910  -5.60006  -38.48772 1.000 33.91926  ? 45  HIS A N   1 
ATOM   323  C  CA  . HIS A 1 45  ? 89.43452  -6.00145  -37.12942 1.000 42.76757  ? 45  HIS A CA  1 
ATOM   324  C  C   . HIS A 1 45  ? 89.44750  -4.79494  -36.19916 1.000 37.23191  ? 45  HIS A C   1 
ATOM   325  O  O   . HIS A 1 45  ? 88.82969  -4.81238  -35.12810 1.000 36.80114  ? 45  HIS A O   1 
ATOM   326  C  CB  . HIS A 1 45  ? 90.79479  -6.70360  -37.12675 1.000 39.90312  ? 45  HIS A CB  1 
ATOM   327  C  CG  . HIS A 1 45  ? 91.02723  -7.57865  -35.93390 1.000 42.52113  ? 45  HIS A CG  1 
ATOM   328  N  ND1 . HIS A 1 45  ? 90.37903  -8.78218  -35.75606 1.000 39.87690  ? 45  HIS A ND1 1 
ATOM   329  C  CD2 . HIS A 1 45  ? 91.84915  -7.43268  -34.86735 1.000 43.40778  ? 45  HIS A CD2 1 
ATOM   330  C  CE1 . HIS A 1 45  ? 90.78806  -9.33695  -34.62875 1.000 40.85394  ? 45  HIS A CE1 1 
ATOM   331  N  NE2 . HIS A 1 45  ? 91.67969  -8.53798  -34.06963 1.000 42.87334  ? 45  HIS A NE2 1 
ATOM   332  N  N   . LEU A 1 46  ? 90.14152  -3.72745  -36.60665 1.000 38.77926  ? 46  LEU A N   1 
ATOM   333  C  CA  . LEU A 1 46  ? 90.22309  -2.52126  -35.78709 1.000 41.76524  ? 46  LEU A CA  1 
ATOM   334  C  C   . LEU A 1 46  ? 88.84269  -1.96963  -35.46858 1.000 37.63498  ? 46  LEU A C   1 
ATOM   335  O  O   . LEU A 1 46  ? 88.60443  -1.46872  -34.36412 1.000 42.46536  ? 46  LEU A O   1 
ATOM   336  C  CB  . LEU A 1 46  ? 91.06269  -1.45713  -36.49604 1.000 34.92823  ? 46  LEU A CB  1 
ATOM   337  C  CG  . LEU A 1 46  ? 92.55643  -1.73762  -36.63910 1.000 35.71331  ? 46  LEU A CG  1 
ATOM   338  C  CD1 . LEU A 1 46  ? 93.25392  -0.58819  -37.36105 1.000 38.90404  ? 46  LEU A CD1 1 
ATOM   339  C  CD2 . LEU A 1 46  ? 93.17783  -1.98424  -35.26683 1.000 36.37079  ? 46  LEU A CD2 1 
ATOM   340  N  N   . ARG A 1 47  ? 87.91582  -2.06385  -36.42246 1.000 36.50795  ? 47  ARG A N   1 
ATOM   341  C  CA  . ARG A 1 47  ? 86.57593  -1.53868  -36.20827 1.000 37.63095  ? 47  ARG A CA  1 
ATOM   342  C  C   . ARG A 1 47  ? 85.78362  -2.36548  -35.20752 1.000 43.83319  ? 47  ARG A C   1 
ATOM   343  O  O   . ARG A 1 47  ? 84.75575  -1.89209  -34.71328 1.000 39.47565  ? 47  ARG A O   1 
ATOM   344  C  CB  . ARG A 1 47  ? 85.81824  -1.46362  -37.53483 1.000 36.99834  ? 47  ARG A CB  1 
ATOM   345  C  CG  . ARG A 1 47  ? 86.30813  -0.36698  -38.46861 1.000 35.39111  ? 47  ARG A CG  1 
ATOM   346  C  CD  . ARG A 1 47  ? 85.75571  -0.56195  -39.87937 1.000 42.07611  ? 47  ARG A CD  1 
ATOM   347  N  NE  . ARG A 1 47  ? 86.08506  0.54743   -40.76689 1.000 40.05268  ? 47  ARG A NE  1 
ATOM   348  C  CZ  . ARG A 1 47  ? 85.20920  1.45014   -41.18689 1.000 46.30491  ? 47  ARG A CZ  1 
ATOM   349  N  NH1 . ARG A 1 47  ? 83.94125  1.40992   -40.81125 1.000 41.72636  ? 47  ARG A NH1 1 
ATOM   350  N  NH2 . ARG A 1 47  ? 85.61253  2.41124   -42.01297 1.000 48.85666  ? 47  ARG A NH2 1 
ATOM   351  N  N   . GLY A 1 48  ? 86.22340  -3.58947  -34.90660 1.000 39.41411  ? 48  GLY A N   1 
ATOM   352  C  CA  . GLY A 1 48  ? 85.54037  -4.37451  -33.89301 1.000 41.52120  ? 48  GLY A CA  1 
ATOM   353  C  C   . GLY A 1 48  ? 85.74902  -3.84673  -32.48806 1.000 38.54525  ? 48  GLY A C   1 
ATOM   354  O  O   . GLY A 1 48  ? 84.90487  -4.05927  -31.61096 1.000 40.54358  ? 48  GLY A O   1 
ATOM   355  N  N   . GLY A 1 49  ? 86.85566  -3.14721  -32.25558 1.000 38.96084  ? 49  GLY A N   1 
ATOM   356  C  CA  . GLY A 1 49  ? 87.16310  -2.65226  -30.92398 1.000 40.79709  ? 49  GLY A CA  1 
ATOM   357  C  C   . GLY A 1 49  ? 87.51467  -3.74724  -29.93936 1.000 46.44223  ? 49  GLY A C   1 
ATOM   358  O  O   . GLY A 1 49  ? 87.08213  -3.69609  -28.78007 1.000 39.20806  ? 49  GLY A O   1 
ATOM   359  N  N   . TYR A 1 50  ? 88.29832  -4.73966  -30.37227 1.000 37.30751  ? 50  TYR A N   1 
ATOM   360  C  CA  . TYR A 1 50  ? 88.53043  -5.91346  -29.53680 1.000 44.20829  ? 50  TYR A CA  1 
ATOM   361  C  C   . TYR A 1 50  ? 89.54866  -5.64471  -28.43656 1.000 39.12093  ? 50  TYR A C   1 
ATOM   362  O  O   . TYR A 1 50  ? 89.46468  -6.25202  -27.36330 1.000 39.06650  ? 50  TYR A O   1 
ATOM   363  C  CB  . TYR A 1 50  ? 88.96216  -7.09094  -30.40901 1.000 38.24994  ? 50  TYR A CB  1 
ATOM   364  C  CG  . TYR A 1 50  ? 87.95999  -7.37271  -31.49972 1.000 44.55722  ? 50  TYR A CG  1 
ATOM   365  C  CD1 . TYR A 1 50  ? 86.66040  -7.74185  -31.18328 1.000 37.06085  ? 50  TYR A CD1 1 
ATOM   366  C  CD2 . TYR A 1 50  ? 88.29776  -7.24277  -32.84246 1.000 39.95145  ? 50  TYR A CD2 1 
ATOM   367  C  CE1 . TYR A 1 50  ? 85.72741  -7.98334  -32.16495 1.000 44.30655  ? 50  TYR A CE1 1 
ATOM   368  C  CE2 . TYR A 1 50  ? 87.36296  -7.48970  -33.83949 1.000 37.72350  ? 50  TYR A CE2 1 
ATOM   369  C  CZ  . TYR A 1 50  ? 86.08135  -7.85925  -33.48948 1.000 41.41682  ? 50  TYR A CZ  1 
ATOM   370  O  OH  . TYR A 1 50  ? 85.14216  -8.10769  -34.45828 1.000 40.52617  ? 50  TYR A OH  1 
ATOM   371  N  N   . ALA A 1 51  ? 90.51847  -4.75863  -28.67960 1.000 37.98379  ? 51  ALA A N   1 
ATOM   372  C  CA  . ALA A 1 51  ? 91.41866  -4.35176  -27.60572 1.000 38.35300  ? 51  ALA A CA  1 
ATOM   373  C  C   . ALA A 1 51  ? 90.68497  -3.49850  -26.58039 1.000 39.65486  ? 51  ALA A C   1 
ATOM   374  O  O   . ALA A 1 51  ? 90.94003  -3.60771  -25.37457 1.000 37.08866  ? 51  ALA A O   1 
ATOM   375  C  CB  . ALA A 1 51  ? 92.61946  -3.60003  -28.17653 1.000 38.06641  ? 51  ALA A CB  1 
ATOM   376  N  N   . ASP A 1 52  ? 89.76047  -2.65335  -27.04430 1.000 37.52269  ? 52  ASP A N   1 
ATOM   377  C  CA  . ASP A 1 52  ? 88.90926  -1.89632  -26.13219 1.000 43.60754  ? 52  ASP A CA  1 
ATOM   378  C  C   . ASP A 1 52  ? 88.11999  -2.83018  -25.22393 1.000 43.35095  ? 52  ASP A C   1 
ATOM   379  O  O   . ASP A 1 52  ? 88.06262  -2.63083  -24.00398 1.000 40.55430  ? 52  ASP A O   1 
ATOM   380  C  CB  . ASP A 1 52  ? 87.96550  -0.99328  -26.92983 1.000 44.50051  ? 52  ASP A CB  1 
ATOM   381  C  CG  . ASP A 1 52  ? 86.98503  -0.24622  -26.04641 1.000 49.26405  ? 52  ASP A CG  1 
ATOM   382  O  OD1 . ASP A 1 52  ? 87.42325  0.64339   -25.29013 1.000 55.02954  ? 52  ASP A OD1 1 
ATOM   383  O  OD2 . ASP A 1 52  ? 85.77424  -0.54940  -26.10869 1.000 58.14889  ? 52  ASP A OD2 1 
ATOM   384  N  N   . LEU A 1 53  ? 87.50771  -3.86173  -25.80916 1.000 40.24116  ? 53  LEU A N   1 
ATOM   385  C  CA  . LEU A 1 53  ? 86.76823  -4.84673  -25.02677 1.000 38.94498  ? 53  LEU A CA  1 
ATOM   386  C  C   . LEU A 1 53  ? 87.67098  -5.52675  -24.00430 1.000 37.76832  ? 53  LEU A C   1 
ATOM   387  O  O   . LEU A 1 53  ? 87.32274  -5.63035  -22.82279 1.000 42.68003  ? 53  LEU A O   1 
ATOM   388  C  CB  . LEU A 1 53  ? 86.13820  -5.87522  -25.96571 1.000 38.34054  ? 53  LEU A CB  1 
ATOM   389  C  CG  . LEU A 1 53  ? 85.36751  -7.05176  -25.37007 1.000 46.38484  ? 53  LEU A CG  1 
ATOM   390  C  CD1 . LEU A 1 53  ? 84.25120  -6.56069  -24.46090 1.000 42.61298  ? 53  LEU A CD1 1 
ATOM   391  C  CD2 . LEU A 1 53  ? 84.81382  -7.91921  -26.49201 1.000 39.76112  ? 53  LEU A CD2 1 
ATOM   392  N  N   . ALA A 1 54  ? 88.84468  -5.98811  -24.44164 1.000 35.65027  ? 54  ALA A N   1 
ATOM   393  C  CA  . ALA A 1 54  ? 89.76496  -6.65798  -23.52726 1.000 40.59055  ? 54  ALA A CA  1 
ATOM   394  C  C   . ALA A 1 54  ? 90.19765  -5.73544  -22.39395 1.000 41.43707  ? 54  ALA A C   1 
ATOM   395  O  O   . ALA A 1 54  ? 90.36797  -6.18109  -21.25335 1.000 37.06882  ? 54  ALA A O   1 
ATOM   396  C  CB  . ALA A 1 54  ? 90.98755  -7.16681  -24.28954 1.000 30.77421  ? 54  ALA A CB  1 
ATOM   397  N  N   . SER A 1 55  ? 90.39529  -4.44801  -22.69098 1.000 35.65260  ? 55  SER A N   1 
ATOM   398  C  CA  . SER A 1 55  ? 90.83457  -3.50595  -21.66832 1.000 38.33789  ? 55  SER A CA  1 
ATOM   399  C  C   . SER A 1 55  ? 89.75280  -3.23348  -20.63184 1.000 34.13733  ? 55  SER A C   1 
ATOM   400  O  O   . SER A 1 55  ? 90.06833  -2.75882  -19.53611 1.000 40.55493  ? 55  SER A O   1 
ATOM   401  C  CB  . SER A 1 55  ? 91.28260  -2.19308  -22.31551 1.000 32.48199  ? 55  SER A CB  1 
ATOM   402  O  OG  . SER A 1 55  ? 90.17860  -1.51659  -22.88652 1.000 38.73966  ? 55  SER A OG  1 
ATOM   403  N  N   . ARG A 1 56  ? 88.49077  -3.51130  -20.95276 1.000 35.46522  ? 56  ARG A N   1 
ATOM   404  C  CA  . ARG A 1 56  ? 87.40170  -3.37332  -19.99554 1.000 35.86647  ? 56  ARG A CA  1 
ATOM   405  C  C   . ARG A 1 56  ? 87.05697  -4.68230  -19.30093 1.000 43.62799  ? 56  ARG A C   1 
ATOM   406  O  O   . ARG A 1 56  ? 86.62173  -4.65960  -18.14543 1.000 38.42450  ? 56  ARG A O   1 
ATOM   407  C  CB  . ARG A 1 56  ? 86.15848  -2.80797  -20.69063 1.000 37.47962  ? 56  ARG A CB  1 
ATOM   408  C  CG  . ARG A 1 56  ? 86.43691  -1.47357  -21.36884 1.000 37.40549  ? 56  ARG A CG  1 
ATOM   409  C  CD  . ARG A 1 56  ? 85.22313  -0.90383  -22.08066 1.000 39.85372  ? 56  ARG A CD  1 
ATOM   410  N  NE  . ARG A 1 56  ? 85.59015  0.29471   -22.82474 1.000 44.68600  ? 56  ARG A NE  1 
ATOM   411  C  CZ  . ARG A 1 56  ? 85.49747  1.53127   -22.35450 1.000 52.22246  ? 56  ARG A CZ  1 
ATOM   412  N  NH1 . ARG A 1 56  ? 84.98714  1.78135   -21.15961 1.000 43.77815  ? 56  ARG A NH1 1 
ATOM   413  N  NH2 . ARG A 1 56  ? 85.92782  2.54271   -23.10286 1.000 59.83207  ? 56  ARG A NH2 1 
ATOM   414  N  N   . PHE A 1 57  ? 87.24287  -5.82014  -19.97681 1.000 39.34728  ? 57  PHE A N   1 
ATOM   415  C  CA  . PHE A 1 57  ? 87.18761  -7.10673  -19.29033 1.000 38.15842  ? 57  PHE A CA  1 
ATOM   416  C  C   . PHE A 1 57  ? 88.32309  -7.23907  -18.28412 1.000 36.06578  ? 57  PHE A C   1 
ATOM   417  O  O   . PHE A 1 57  ? 88.14449  -7.82304  -17.20737 1.000 35.95171  ? 57  PHE A O   1 
ATOM   418  C  CB  . PHE A 1 57  ? 87.26061  -8.25277  -20.30241 1.000 33.70337  ? 57  PHE A CB  1 
ATOM   419  C  CG  . PHE A 1 57  ? 85.95478  -8.57365  -20.96967 1.000 33.94395  ? 57  PHE A CG  1 
ATOM   420  C  CD1 . PHE A 1 57  ? 84.75609  -8.18908  -20.40410 1.000 32.86661  ? 57  PHE A CD1 1 
ATOM   421  C  CD2 . PHE A 1 57  ? 85.93322  -9.27641  -22.16718 1.000 35.87138  ? 57  PHE A CD2 1 
ATOM   422  C  CE1 . PHE A 1 57  ? 83.55531  -8.49772  -21.01640 1.000 34.95987  ? 57  PHE A CE1 1 
ATOM   423  C  CE2 . PHE A 1 57  ? 84.73846  -9.59382  -22.77992 1.000 31.86112  ? 57  PHE A CE2 1 
ATOM   424  C  CZ  . PHE A 1 57  ? 83.54767  -9.20177  -22.20767 1.000 39.49280  ? 57  PHE A CZ  1 
ATOM   425  N  N   . TYR A 1 58  ? 89.50005  -6.71007  -18.62033 1.000 33.27458  ? 58  TYR A N   1 
ATOM   426  C  CA  . TYR A 1 58  ? 90.72039  -6.91007  -17.84126 1.000 34.69922  ? 58  TYR A CA  1 
ATOM   427  C  C   . TYR A 1 58  ? 91.36720  -5.57829  -17.45664 1.000 37.17638  ? 58  TYR A C   1 
ATOM   428  O  O   . TYR A 1 58  ? 92.54177  -5.33823  -17.75982 1.000 34.66223  ? 58  TYR A O   1 
ATOM   429  C  CB  . TYR A 1 58  ? 91.69521  -7.77789  -18.63410 1.000 28.50264  ? 58  TYR A CB  1 
ATOM   430  C  CG  . TYR A 1 58  ? 91.03661  -8.98619  -19.26358 1.000 35.35037  ? 58  TYR A CG  1 
ATOM   431  C  CD1 . TYR A 1 58  ? 90.30287  -9.88002  -18.49142 1.000 33.81231  ? 58  TYR A CD1 1 
ATOM   432  C  CD2 . TYR A 1 58  ? 91.11938  -9.21678  -20.63356 1.000 32.37139  ? 58  TYR A CD2 1 
ATOM   433  C  CE1 . TYR A 1 58  ? 89.68742  -10.97434 -19.05785 1.000 35.16795  ? 58  TYR A CE1 1 
ATOM   434  C  CE2 . TYR A 1 58  ? 90.50300  -10.31370 -21.20918 1.000 31.11257  ? 58  TYR A CE2 1 
ATOM   435  C  CZ  . TYR A 1 58  ? 89.79175  -11.18834 -20.41469 1.000 37.00731  ? 58  TYR A CZ  1 
ATOM   436  O  OH  . TYR A 1 58  ? 89.17721  -12.27780 -20.97292 1.000 35.86442  ? 58  TYR A OH  1 
ATOM   437  N  N   . PRO A 1 59  ? 90.63787  -4.69814  -16.76047 1.000 35.54580  ? 59  PRO A N   1 
ATOM   438  C  CA  . PRO A 1 59  ? 91.23348  -3.40147  -16.39126 1.000 37.12454  ? 59  PRO A CA  1 
ATOM   439  C  C   . PRO A 1 59  ? 92.40132  -3.53570  -15.43417 1.000 41.00717  ? 59  PRO A C   1 
ATOM   440  O  O   . PRO A 1 59  ? 93.25472  -2.64075  -15.37971 1.000 37.25132  ? 59  PRO A O   1 
ATOM   441  C  CB  . PRO A 1 59  ? 90.06226  -2.64688  -15.74858 1.000 33.10628  ? 59  PRO A CB  1 
ATOM   442  C  CG  . PRO A 1 59  ? 89.21100  -3.72741  -15.17487 1.000 39.77137  ? 59  PRO A CG  1 
ATOM   443  C  CD  . PRO A 1 59  ? 89.31009  -4.88245  -16.14736 1.000 34.13108  ? 59  PRO A CD  1 
ATOM   444  N  N   . HIS A 1 60  ? 92.47597  -4.63991  -14.69625 1.000 36.45264  ? 60  HIS A N   1 
ATOM   445  C  CA  . HIS A 1 60  ? 93.56626  -4.90596  -13.77021 1.000 37.88465  ? 60  HIS A CA  1 
ATOM   446  C  C   . HIS A 1 60  ? 94.84619  -5.35976  -14.45828 1.000 36.57707  ? 60  HIS A C   1 
ATOM   447  O  O   . HIS A 1 60  ? 95.86274  -5.53594  -13.77728 1.000 41.49256  ? 60  HIS A O   1 
ATOM   448  C  CB  . HIS A 1 60  ? 93.12922  -5.97216  -12.76247 1.000 39.49093  ? 60  HIS A CB  1 
ATOM   449  C  CG  . HIS A 1 60  ? 92.61474  -7.22917  -13.39790 1.000 39.06717  ? 60  HIS A CG  1 
ATOM   450  N  ND1 . HIS A 1 60  ? 91.47103  -7.26169  -14.16738 1.000 38.60827  ? 60  HIS A ND1 1 
ATOM   451  C  CD2 . HIS A 1 60  ? 93.08473  -8.49912  -13.37183 1.000 38.50300  ? 60  HIS A CD2 1 
ATOM   452  C  CE1 . HIS A 1 60  ? 91.25850  -8.49630  -14.58677 1.000 38.50505  ? 60  HIS A CE1 1 
ATOM   453  N  NE2 . HIS A 1 60  ? 92.22218  -9.26743  -14.11628 1.000 33.30354  ? 60  HIS A NE2 1 
ATOM   454  N  N   . ALA A 1 61  ? 94.82770  -5.55574  -15.77386 1.000 37.88919  ? 61  ALA A N   1 
ATOM   455  C  CA  . ALA A 1 61  ? 95.96970  -6.09312  -16.49903 1.000 36.47096  ? 61  ALA A CA  1 
ATOM   456  C  C   . ALA A 1 61  ? 96.66427  -5.00307  -17.30393 1.000 39.83926  ? 61  ALA A C   1 
ATOM   457  O  O   . ALA A 1 61  ? 96.01497  -4.10672  -17.84964 1.000 38.53902  ? 61  ALA A O   1 
ATOM   458  C  CB  . ALA A 1 61  ? 95.53880  -7.22549  -17.43324 1.000 34.05396  ? 61  ALA A CB  1 
ATOM   459  N  N   . THR A 1 62  ? 97.99181  -5.09032  -17.37284 1.000 38.58374  ? 62  THR A N   1 
ATOM   460  C  CA  . THR A 1 62  ? 98.80332  -4.23135  -18.22265 1.000 39.86722  ? 62  THR A CA  1 
ATOM   461  C  C   . THR A 1 62  ? 99.84578  -5.09264  -18.92089 1.000 39.45339  ? 62  THR A C   1 
ATOM   462  O  O   . THR A 1 62  ? 100.04019 -6.26287  -18.58451 1.000 39.34771  ? 62  THR A O   1 
ATOM   463  C  CB  . THR A 1 62  ? 99.50478  -3.11424  -17.43096 1.000 49.35798  ? 62  THR A CB  1 
ATOM   464  O  OG1 . THR A 1 62  ? 100.44894 -3.69356  -16.52141 1.000 48.39756  ? 62  THR A OG1 1 
ATOM   465  C  CG2 . THR A 1 62  ? 98.50248  -2.27184  -16.64952 1.000 43.64342  ? 62  THR A CG2 1 
ATOM   466  N  N   . GLY A 1 63  ? 100.51865 -4.49911  -19.90425 1.000 40.22111  ? 63  GLY A N   1 
ATOM   467  C  CA  . GLY A 1 63  ? 101.64824 -5.15841  -20.53999 1.000 38.59114  ? 63  GLY A CA  1 
ATOM   468  C  C   . GLY A 1 63  ? 101.27829 -6.47272  -21.19960 1.000 35.93434  ? 63  GLY A C   1 
ATOM   469  O  O   . GLY A 1 63  ? 100.21299 -6.61889  -21.80884 1.000 37.58663  ? 63  GLY A O   1 
ATOM   470  N  N   . ALA A 1 64  ? 102.17894 -7.45241  -21.07100 1.000 39.43775  ? 64  ALA A N   1 
ATOM   471  C  CA  . ALA A 1 64  ? 101.97819 -8.74593  -21.71785 1.000 38.45341  ? 64  ALA A CA  1 
ATOM   472  C  C   . ALA A 1 64  ? 100.71547 -9.44320  -21.22384 1.000 39.35786  ? 64  ALA A C   1 
ATOM   473  O  O   . ALA A 1 64  ? 100.08326 -10.18354 -21.98459 1.000 42.48968  ? 64  ALA A O   1 
ATOM   474  C  CB  . ALA A 1 64  ? 103.20081 -9.63671  -21.49638 1.000 36.91258  ? 64  ALA A CB  1 
ATOM   475  N  N   . ASP A 1 65  ? 100.33162 -9.22202  -19.96224 1.000 35.70218  ? 65  ASP A N   1 
ATOM   476  C  CA  . ASP A 1 65  ? 99.08686  -9.79500  -19.45537 1.000 39.18590  ? 65  ASP A CA  1 
ATOM   477  C  C   . ASP A 1 65  ? 97.88257  -9.22968  -20.19356 1.000 35.51412  ? 65  ASP A C   1 
ATOM   478  O  O   . ASP A 1 65  ? 96.97408  -9.97527  -20.57532 1.000 37.00181  ? 65  ASP A O   1 
ATOM   479  C  CB  . ASP A 1 65  ? 98.95277  -9.54446  -17.94934 1.000 36.19035  ? 65  ASP A CB  1 
ATOM   480  C  CG  . ASP A 1 65  ? 99.95776  -10.33543 -17.13461 1.000 42.66130  ? 65  ASP A CG  1 
ATOM   481  O  OD1 . ASP A 1 65  ? 100.46618 -11.35629 -17.64884 1.000 45.95083  ? 65  ASP A OD1 1 
ATOM   482  O  OD2 . ASP A 1 65  ? 100.23619 -9.94370  -15.98105 1.000 49.26678  ? 65  ASP A OD2 1 
ATOM   483  N  N   . LEU A 1 66  ? 97.85459  -7.91167  -20.40082 1.000 35.58248  ? 66  LEU A N   1 
ATOM   484  C  CA  . LEU A 1 66  ? 96.75997  -7.30899  -21.15379 1.000 37.18946  ? 66  LEU A CA  1 
ATOM   485  C  C   . LEU A 1 66  ? 96.79341  -7.74150  -22.61587 1.000 33.12538  ? 66  LEU A C   1 
ATOM   486  O  O   . LEU A 1 66  ? 95.73916  -7.95638  -23.22465 1.000 32.96357  ? 66  LEU A O   1 
ATOM   487  C  CB  . LEU A 1 66  ? 96.81710  -5.78515  -21.03323 1.000 32.32496  ? 66  LEU A CB  1 
ATOM   488  C  CG  . LEU A 1 66  ? 95.80447  -4.98433  -21.85500 1.000 36.77956  ? 66  LEU A CG  1 
ATOM   489  C  CD1 . LEU A 1 66  ? 94.37979  -5.41311  -21.53594 1.000 35.52298  ? 66  LEU A CD1 1 
ATOM   490  C  CD2 . LEU A 1 66  ? 95.98519  -3.49287  -21.61099 1.000 37.96112  ? 66  LEU A CD2 1 
ATOM   491  N  N   . ASP A 1 67  ? 97.99422  -7.87928  -23.19164 1.000 31.92545  ? 67  ASP A N   1 
ATOM   492  C  CA  . ASP A 1 67  ? 98.11367  -8.34376  -24.57334 1.000 39.05712  ? 67  ASP A CA  1 
ATOM   493  C  C   . ASP A 1 67  ? 97.49385  -9.72338  -24.75158 1.000 39.29719  ? 67  ASP A C   1 
ATOM   494  O  O   . ASP A 1 67  ? 96.84468  -9.99218  -25.76904 1.000 36.38285  ? 67  ASP A O   1 
ATOM   495  C  CB  . ASP A 1 67  ? 99.58167  -8.36539  -24.99990 1.000 38.61914  ? 67  ASP A CB  1 
ATOM   496  C  CG  . ASP A 1 67  ? 100.15407 -6.97326  -25.19795 1.000 42.21788  ? 67  ASP A CG  1 
ATOM   497  O  OD1 . ASP A 1 67  ? 99.35901  -6.02004  -25.33372 1.000 41.60587  ? 67  ASP A OD1 1 
ATOM   498  O  OD2 . ASP A 1 67  ? 101.39568 -6.83422  -25.23252 1.000 46.07325  ? 67  ASP A OD2 1 
ATOM   499  N  N   . LEU A 1 68  ? 97.68957  -10.61505 -23.77544 1.000 38.38184  ? 68  LEU A N   1 
ATOM   500  C  CA  . LEU A 1 68  ? 97.04527  -11.92258 -23.83711 1.000 35.55668  ? 68  LEU A CA  1 
ATOM   501  C  C   . LEU A 1 68  ? 95.52944  -11.78138 -23.86190 1.000 32.26109  ? 68  LEU A C   1 
ATOM   502  O  O   . LEU A 1 68  ? 94.84002  -12.51655 -24.57889 1.000 35.54114  ? 68  LEU A O   1 
ATOM   503  C  CB  . LEU A 1 68  ? 97.49261  -12.78707 -22.65621 1.000 35.04004  ? 68  LEU A CB  1 
ATOM   504  C  CG  . LEU A 1 68  ? 96.83078  -14.16222 -22.53633 1.000 34.20800  ? 68  LEU A CG  1 
ATOM   505  C  CD1 . LEU A 1 68  ? 97.08873  -14.99349 -23.79030 1.000 33.88066  ? 68  LEU A CD1 1 
ATOM   506  C  CD2 . LEU A 1 68  ? 97.31956  -14.89493 -21.28537 1.000 34.20191  ? 68  LEU A CD2 1 
ATOM   507  N  N   . GLY A 1 69  ? 94.99409  -10.83056 -23.09554 1.000 32.48064  ? 69  GLY A N   1 
ATOM   508  C  CA  . GLY A 1 69  ? 93.56320  -10.58031 -23.13684 1.000 33.03556  ? 69  GLY A CA  1 
ATOM   509  C  C   . GLY A 1 69  ? 93.10663  -10.02867 -24.47240 1.000 33.58135  ? 69  GLY A C   1 
ATOM   510  O  O   . GLY A 1 69  ? 92.03011  -10.38296 -24.96404 1.000 32.80049  ? 69  GLY A O   1 
ATOM   511  N  N   . VAL A 1 70  ? 93.91562  -9.15266  -25.07506 1.000 33.83035  ? 70  VAL A N   1 
ATOM   512  C  CA  . VAL A 1 70  ? 93.59344  -8.61872  -26.39826 1.000 32.99469  ? 70  VAL A CA  1 
ATOM   513  C  C   . VAL A 1 70  ? 93.58130  -9.74040  -27.43213 1.000 35.93670  ? 70  VAL A C   1 
ATOM   514  O  O   . VAL A 1 70  ? 92.66303  -9.84399  -28.25468 1.000 32.96783  ? 70  VAL A O   1 
ATOM   515  C  CB  . VAL A 1 70  ? 94.58814  -7.50713  -26.78600 1.000 34.68104  ? 70  VAL A CB  1 
ATOM   516  C  CG1 . VAL A 1 70  ? 94.31112  -6.99858  -28.20952 1.000 33.61197  ? 70  VAL A CG1 1 
ATOM   517  C  CG2 . VAL A 1 70  ? 94.54529  -6.35840  -25.77690 1.000 35.15458  ? 70  VAL A CG2 1 
ATOM   518  N  N   . ASP A 1 71  ? 94.60094  -10.60371 -27.39797 1.000 32.67935  ? 71  ASP A N   1 
ATOM   519  C  CA  . ASP A 1 71  ? 94.69327  -11.68056 -28.37816 1.000 36.16855  ? 71  ASP A CA  1 
ATOM   520  C  C   . ASP A 1 71  ? 93.53537  -12.66107 -28.23828 1.000 36.69152  ? 71  ASP A C   1 
ATOM   521  O  O   . ASP A 1 71  ? 93.05466  -13.20655 -29.23823 1.000 38.57311  ? 71  ASP A O   1 
ATOM   522  C  CB  . ASP A 1 71  ? 96.03837  -12.39658 -28.24435 1.000 32.04548  ? 71  ASP A CB  1 
ATOM   523  C  CG  . ASP A 1 71  ? 97.21187  -11.47940 -28.54656 1.000 34.20937  ? 71  ASP A CG  1 
ATOM   524  O  OD1 . ASP A 1 71  ? 96.96830  -10.37784 -29.08043 1.000 35.87188  ? 71  ASP A OD1 1 
ATOM   525  O  OD2 . ASP A 1 71  ? 98.36779  -11.84459 -28.24423 1.000 36.31221  ? 71  ASP A OD2 1 
ATOM   526  N  N   . LEU A 1 72  ? 93.06074  -12.89033 -27.01081 1.000 34.72067  ? 72  LEU A N   1 
ATOM   527  C  CA  . LEU A 1 72  ? 91.90655  -13.76769 -26.83189 1.000 36.47488  ? 72  LEU A CA  1 
ATOM   528  C  C   . LEU A 1 72  ? 90.66783  -13.18073 -27.49506 1.000 32.39817  ? 72  LEU A C   1 
ATOM   529  O  O   . LEU A 1 72  ? 89.94987  -13.87767 -28.22111 1.000 35.81963  ? 72  LEU A O   1 
ATOM   530  C  CB  . LEU A 1 72  ? 91.64113  -14.02678 -25.34706 1.000 27.89374  ? 72  LEU A CB  1 
ATOM   531  C  CG  . LEU A 1 72  ? 90.36587  -14.84994 -25.11723 1.000 34.05794  ? 72  LEU A CG  1 
ATOM   532  C  CD1 . LEU A 1 72  ? 90.46098  -16.18908 -25.83272 1.000 33.10219  ? 72  LEU A CD1 1 
ATOM   533  C  CD2 . LEU A 1 72  ? 90.06268  -15.06790 -23.63941 1.000 32.28886  ? 72  LEU A CD2 1 
ATOM   534  N  N   . MET A 1 73  ? 90.39039  -11.89924 -27.24214 1.000 33.77703  ? 73  MET A N   1 
ATOM   535  C  CA  . MET A 1 73  ? 89.26297  -11.25311 -27.90538 1.000 33.08062  ? 73  MET A CA  1 
ATOM   536  C  C   . MET A 1 73  ? 89.45014  -11.25886 -29.41694 1.000 35.11906  ? 73  MET A C   1 
ATOM   537  O  O   . MET A 1 73  ? 88.51027  -11.55703 -30.16279 1.000 38.77444  ? 73  MET A O   1 
ATOM   538  C  CB  . MET A 1 73  ? 89.08791  -9.82313  -27.38908 1.000 40.08455  ? 73  MET A CB  1 
ATOM   539  C  CG  . MET A 1 73  ? 88.78267  -9.70255  -25.89155 1.000 38.01405  ? 73  MET A CG  1 
ATOM   540  S  SD  . MET A 1 73  ? 87.27970  -10.57793 -25.40171 1.000 39.90961  ? 73  MET A SD  1 
ATOM   541  C  CE  . MET A 1 73  ? 87.97903  -12.03045 -24.61872 1.000 37.99190  ? 73  MET A CE  1 
ATOM   542  N  N   . SER A 1 74  ? 90.66177  -10.94339 -29.88648 1.000 36.50679  ? 74  SER A N   1 
ATOM   543  C  CA  . SER A 1 74  ? 90.93710  -10.97946 -31.32087 1.000 38.58354  ? 74  SER A CA  1 
ATOM   544  C  C   . SER A 1 74  ? 90.65334  -12.36013 -31.89314 1.000 36.56142  ? 74  SER A C   1 
ATOM   545  O  O   . SER A 1 74  ? 89.89951  -12.50039 -32.86227 1.000 35.80498  ? 74  SER A O   1 
ATOM   546  C  CB  . SER A 1 74  ? 92.38838  -10.58513 -31.59194 1.000 34.43494  ? 74  SER A CB  1 
ATOM   547  O  OG  . SER A 1 74  ? 92.59165  -9.19589  -31.42130 1.000 33.99895  ? 74  SER A OG  1 
ATOM   548  N  N   . TRP A 1 75  ? 91.23773  -13.39710 -31.28462 1.000 40.43168  ? 75  TRP A N   1 
ATOM   549  C  CA  . TRP A 1 75  ? 91.06404  -14.75280 -31.79188 1.000 36.26820  ? 75  TRP A CA  1 
ATOM   550  C  C   . TRP A 1 75  ? 89.60703  -15.18845 -31.72719 1.000 34.40108  ? 75  TRP A C   1 
ATOM   551  O  O   . TRP A 1 75  ? 89.09918  -15.81200 -32.66567 1.000 37.29205  ? 75  TRP A O   1 
ATOM   552  C  CB  . TRP A 1 75  ? 91.94474  -15.73783 -31.01514 1.000 36.29766  ? 75  TRP A CB  1 
ATOM   553  C  CG  . TRP A 1 75  ? 91.69414  -17.15754 -31.44233 1.000 38.33901  ? 75  TRP A CG  1 
ATOM   554  C  CD1 . TRP A 1 75  ? 92.34496  -17.84448 -32.42701 1.000 35.24410  ? 75  TRP A CD1 1 
ATOM   555  C  CD2 . TRP A 1 75  ? 90.68623  -18.04468 -30.93507 1.000 39.61193  ? 75  TRP A CD2 1 
ATOM   556  N  NE1 . TRP A 1 75  ? 91.81397  -19.10620 -32.55431 1.000 35.59238  ? 75  TRP A NE1 1 
ATOM   557  C  CE2 . TRP A 1 75  ? 90.79292  -19.25322 -31.65315 1.000 37.79608  ? 75  TRP A CE2 1 
ATOM   558  C  CE3 . TRP A 1 75  ? 89.70912  -17.93610 -29.93977 1.000 32.93471  ? 75  TRP A CE3 1 
ATOM   559  C  CZ2 . TRP A 1 75  ? 89.95963  -20.34469 -31.40699 1.000 34.78643  ? 75  TRP A CZ2 1 
ATOM   560  C  CZ3 . TRP A 1 75  ? 88.87930  -19.01674 -29.70157 1.000 38.67748  ? 75  TRP A CZ3 1 
ATOM   561  C  CH2 . TRP A 1 75  ? 89.01169  -20.20652 -30.43024 1.000 40.17725  ? 75  TRP A CH2 1 
ATOM   562  N  N   . ALA A 1 76  ? 88.91789  -14.87192 -30.62845 1.000 35.56286  ? 76  ALA A N   1 
ATOM   563  C  CA  . ALA A 1 76  ? 87.57210  -15.40138 -30.42676 1.000 39.59165  ? 76  ALA A CA  1 
ATOM   564  C  C   . ALA A 1 76  ? 86.60006  -14.89982 -31.48166 1.000 38.40747  ? 76  ALA A C   1 
ATOM   565  O  O   . ALA A 1 76  ? 85.70268  -15.64121 -31.89897 1.000 37.13801  ? 76  ALA A O   1 
ATOM   566  C  CB  . ALA A 1 76  ? 87.06264  -15.04233 -29.02887 1.000 35.02725  ? 76  ALA A CB  1 
ATOM   567  N  N   . PHE A 1 77  ? 86.74772  -13.65004 -31.91402 1.000 38.08245  ? 77  PHE A N   1 
ATOM   568  C  CA  . PHE A 1 77  ? 85.80990  -13.11243 -32.88917 1.000 37.11812  ? 77  PHE A CA  1 
ATOM   569  C  C   . PHE A 1 77  ? 86.17808  -13.50880 -34.31153 1.000 35.29200  ? 77  PHE A C   1 
ATOM   570  O  O   . PHE A 1 77  ? 85.28545  -13.67897 -35.14806 1.000 36.94625  ? 77  PHE A O   1 
ATOM   571  C  CB  . PHE A 1 77  ? 85.71686  -11.59547 -32.74169 1.000 34.79216  ? 77  PHE A CB  1 
ATOM   572  C  CG  . PHE A 1 77  ? 84.87538  -11.16706 -31.57716 1.000 42.60719  ? 77  PHE A CG  1 
ATOM   573  C  CD1 . PHE A 1 77  ? 83.50534  -11.02430 -31.71333 1.000 43.51148  ? 77  PHE A CD1 1 
ATOM   574  C  CD2 . PHE A 1 77  ? 85.44870  -10.93782 -30.33807 1.000 40.39016  ? 77  PHE A CD2 1 
ATOM   575  C  CE1 . PHE A 1 77  ? 82.72246  -10.64064 -30.64031 1.000 48.37274  ? 77  PHE A CE1 1 
ATOM   576  C  CE2 . PHE A 1 77  ? 84.67394  -10.55339 -29.26067 1.000 42.42156  ? 77  PHE A CE2 1 
ATOM   577  C  CZ  . PHE A 1 77  ? 83.30770  -10.40449 -29.41157 1.000 46.28727  ? 77  PHE A CZ  1 
ATOM   578  N  N   . LEU A 1 78  ? 87.47137  -13.66618 -34.59917 1.000 34.34447  ? 78  LEU A N   1 
ATOM   579  C  CA  . LEU A 1 78  ? 87.88074  -14.25999 -35.86691 1.000 38.28851  ? 78  LEU A CA  1 
ATOM   580  C  C   . LEU A 1 78  ? 87.36342  -15.68583 -35.98076 1.000 44.38731  ? 78  LEU A C   1 
ATOM   581  O  O   . LEU A 1 78  ? 86.79299  -16.07215 -37.00636 1.000 40.38023  ? 78  LEU A O   1 
ATOM   582  C  CB  . LEU A 1 78  ? 89.40324  -14.22759 -35.99368 1.000 33.65861  ? 78  LEU A CB  1 
ATOM   583  C  CG  . LEU A 1 78  ? 89.99096  -12.84603 -36.27288 1.000 41.90260  ? 78  LEU A CG  1 
ATOM   584  C  CD1 . LEU A 1 78  ? 91.49194  -12.82586 -36.01115 1.000 35.76231  ? 78  LEU A CD1 1 
ATOM   585  C  CD2 . LEU A 1 78  ? 89.67970  -12.41674 -37.70633 1.000 37.78828  ? 78  LEU A CD2 1 
ATOM   586  N  N   . PHE A 1 79  ? 87.54696  -16.47863 -34.92137 1.000 39.56716  ? 79  PHE A N   1 
ATOM   587  C  CA  . PHE A 1 79  ? 87.01557  -17.83737 -34.88534 1.000 39.89388  ? 79  PHE A CA  1 
ATOM   588  C  C   . PHE A 1 79  ? 85.50968  -17.84895 -35.12165 1.000 40.29423  ? 79  PHE A C   1 
ATOM   589  O  O   . PHE A 1 79  ? 85.00257  -18.62116 -35.94257 1.000 36.41730  ? 79  PHE A O   1 
ATOM   590  C  CB  . PHE A 1 79  ? 87.35864  -18.48633 -33.53951 1.000 35.95890  ? 79  PHE A CB  1 
ATOM   591  C  CG  . PHE A 1 79  ? 86.74776  -19.84560 -33.34049 1.000 36.14806  ? 79  PHE A CG  1 
ATOM   592  C  CD1 . PHE A 1 79  ? 87.33617  -20.97534 -33.89021 1.000 39.14011  ? 79  PHE A CD1 1 
ATOM   593  C  CD2 . PHE A 1 79  ? 85.59346  -19.99578 -32.59073 1.000 40.63433  ? 79  PHE A CD2 1 
ATOM   594  C  CE1 . PHE A 1 79  ? 86.77655  -22.23153 -33.69979 1.000 39.38676  ? 79  PHE A CE1 1 
ATOM   595  C  CE2 . PHE A 1 79  ? 85.02814  -21.24558 -32.39594 1.000 43.36588  ? 79  PHE A CE2 1 
ATOM   596  C  CZ  . PHE A 1 79  ? 85.62069  -22.36576 -32.95137 1.000 41.42908  ? 79  PHE A CZ  1 
ATOM   597  N  N   . ASP A 1 80  ? 84.77699  -16.99061 -34.40710 1.000 39.38231  ? 80  ASP A N   1 
ATOM   598  C  CA  . ASP A 1 80  ? 83.32280  -16.98065 -34.52450 1.000 40.31345  ? 80  ASP A CA  1 
ATOM   599  C  C   . ASP A 1 80  ? 82.86359  -16.61136 -35.93069 1.000 41.44474  ? 80  ASP A C   1 
ATOM   600  O  O   . ASP A 1 80  ? 81.81632  -17.08706 -36.38535 1.000 41.34213  ? 80  ASP A O   1 
ATOM   601  C  CB  . ASP A 1 80  ? 82.72346  -16.01296 -33.50675 1.000 38.18520  ? 80  ASP A CB  1 
ATOM   602  C  CG  . ASP A 1 80  ? 81.21887  -15.94716 -33.58964 1.000 46.92144  ? 80  ASP A CG  1 
ATOM   603  O  OD1 . ASP A 1 80  ? 80.56118  -16.94056 -33.22041 1.000 51.79379  ? 80  ASP A OD1 1 
ATOM   604  O  OD2 . ASP A 1 80  ? 80.69170  -14.89842 -34.01594 1.000 51.90343  ? 80  ASP A OD2 1 
ATOM   605  N  N   . ASP A 1 81  ? 83.62065  -15.76641 -36.63263 1.000 38.25681  ? 81  ASP A N   1 
ATOM   606  C  CA  . ASP A 1 81  ? 83.22899  -15.37005 -37.98038 1.000 44.94578  ? 81  ASP A CA  1 
ATOM   607  C  C   . ASP A 1 81  ? 83.36267  -16.49944 -38.99477 1.000 45.28538  ? 81  ASP A C   1 
ATOM   608  O  O   . ASP A 1 81  ? 82.81190  -16.38564 -40.09427 1.000 47.88375  ? 81  ASP A O   1 
ATOM   609  C  CB  . ASP A 1 81  ? 84.05198  -14.16309 -38.43371 1.000 49.55867  ? 81  ASP A CB  1 
ATOM   610  C  CG  . ASP A 1 81  ? 83.64238  -12.88323 -37.73054 1.000 52.57959  ? 81  ASP A CG  1 
ATOM   611  O  OD1 . ASP A 1 81  ? 82.50273  -12.82286 -37.22170 1.000 53.67577  ? 81  ASP A OD1 1 
ATOM   612  O  OD2 . ASP A 1 81  ? 84.45616  -11.93697 -37.68959 1.000 54.52566  ? 81  ASP A OD2 1 
ATOM   613  N  N   . LEU A 1 82  ? 84.06828  -17.58005 -38.65673 1.000 46.16254  ? 82  LEU A N   1 
ATOM   614  C  CA  . LEU A 1 82  ? 84.18027  -18.72869 -39.54879 1.000 44.91391  ? 82  LEU A CA  1 
ATOM   615  C  C   . LEU A 1 82  ? 82.90610  -19.55929 -39.61417 1.000 43.73288  ? 82  LEU A C   1 
ATOM   616  O  O   . LEU A 1 82  ? 82.84670  -20.50396 -40.40854 1.000 46.68295  ? 82  LEU A O   1 
ATOM   617  C  CB  . LEU A 1 82  ? 85.34463  -19.61690 -39.11110 1.000 40.62506  ? 82  LEU A CB  1 
ATOM   618  C  CG  . LEU A 1 82  ? 86.72400  -18.96151 -39.10606 1.000 47.24731  ? 82  LEU A CG  1 
ATOM   619  C  CD1 . LEU A 1 82  ? 87.77684  -19.93937 -38.61966 1.000 35.97317  ? 82  LEU A CD1 1 
ATOM   620  C  CD2 . LEU A 1 82  ? 87.06503  -18.45777 -40.49515 1.000 45.25297  ? 82  LEU A CD2 1 
ATOM   621  N  N   . PHE A 1 83  ? 81.89582  -19.23841 -38.80756 1.000 42.59770  ? 83  PHE A N   1 
ATOM   622  C  CA  . PHE A 1 83  ? 80.66606  -20.01724 -38.74086 1.000 40.70132  ? 83  PHE A CA  1 
ATOM   623  C  C   . PHE A 1 83  ? 79.44787  -19.20803 -39.16399 1.000 47.79870  ? 83  PHE A C   1 
ATOM   624  O  O   . PHE A 1 83  ? 78.31296  -19.63998 -38.92754 1.000 51.60846  ? 83  PHE A O   1 
ATOM   625  C  CB  . PHE A 1 83  ? 80.47668  -20.58025 -37.32614 1.000 43.30819  ? 83  PHE A CB  1 
ATOM   626  C  CG  . PHE A 1 83  ? 81.61503  -21.45558 -36.87188 1.000 45.66067  ? 83  PHE A CG  1 
ATOM   627  C  CD1 . PHE A 1 83  ? 81.58583  -22.82443 -37.08741 1.000 42.45947  ? 83  PHE A CD1 1 
ATOM   628  C  CD2 . PHE A 1 83  ? 82.72451  -20.90537 -36.25087 1.000 41.84015  ? 83  PHE A CD2 1 
ATOM   629  C  CE1 . PHE A 1 83  ? 82.63686  -23.62769 -36.68223 1.000 39.59228  ? 83  PHE A CE1 1 
ATOM   630  C  CE2 . PHE A 1 83  ? 83.77816  -21.70214 -35.84554 1.000 39.54296  ? 83  PHE A CE2 1 
ATOM   631  C  CZ  . PHE A 1 83  ? 83.73512  -23.06531 -36.06212 1.000 43.95631  ? 83  PHE A CZ  1 
ATOM   632  N  N   . ASP A 1 84  ? 79.65363  -18.04661 -39.78688 1.000 51.99698  ? 84  ASP A N   1 
ATOM   633  C  CA  . ASP A 1 84  ? 78.53616  -17.25492 -40.28606 1.000 60.02783  ? 84  ASP A CA  1 
ATOM   634  C  C   . ASP A 1 84  ? 77.98689  -17.79471 -41.59874 1.000 57.49281  ? 84  ASP A C   1 
ATOM   635  O  O   . ASP A 1 84  ? 76.81757  -17.55534 -41.91828 1.000 63.11117  ? 84  ASP A O   1 
ATOM   636  C  CB  . ASP A 1 84  ? 78.96093  -15.79890 -40.46922 1.000 59.86435  ? 84  ASP A CB  1 
ATOM   637  C  CG  . ASP A 1 84  ? 78.60798  -14.93552 -39.27950 1.000 66.44785  ? 84  ASP A CG  1 
ATOM   638  O  OD1 . ASP A 1 84  ? 77.95905  -15.44689 -38.34104 1.000 69.78223  ? 84  ASP A OD1 1 
ATOM   639  O  OD2 . ASP A 1 84  ? 78.97739  -13.74081 -39.28372 1.000 75.74339  ? 84  ASP A OD2 1 
ATOM   640  N  N   . GLY A 1 85  ? 78.80065  -18.51488 -42.36489 1.000 56.35631  ? 85  GLY A N   1 
ATOM   641  C  CA  . GLY A 1 85  ? 78.38099  -19.02662 -43.64641 1.000 57.14935  ? 85  GLY A CA  1 
ATOM   642  C  C   . GLY A 1 85  ? 77.92874  -20.47208 -43.58929 1.000 57.17717  ? 85  GLY A C   1 
ATOM   643  O  O   . GLY A 1 85  ? 77.41453  -20.94899 -42.57204 1.000 56.58929  ? 85  GLY A O   1 
ATOM   644  N  N   . PRO A 1 86  ? 78.11328  -21.19741 -44.69752 1.000 59.45406  ? 86  PRO A N   1 
ATOM   645  C  CA  . PRO A 1 86  ? 77.62139  -22.58585 -44.76298 1.000 54.65445  ? 86  PRO A CA  1 
ATOM   646  C  C   . PRO A 1 86  ? 78.17613  -23.50468 -43.68486 1.000 52.72584  ? 86  PRO A C   1 
ATOM   647  O  O   . PRO A 1 86  ? 77.47109  -24.43195 -43.26689 1.000 53.26982  ? 86  PRO A O   1 
ATOM   648  C  CB  . PRO A 1 86  ? 78.05586  -23.03662 -46.16426 1.000 55.14465  ? 86  PRO A CB  1 
ATOM   649  C  CG  . PRO A 1 86  ? 78.09192  -21.77293 -46.95938 1.000 55.42002  ? 86  PRO A CG  1 
ATOM   650  C  CD  . PRO A 1 86  ? 78.56584  -20.70484 -46.01065 1.000 54.19555  ? 86  PRO A CD  1 
ATOM   651  N  N   . ARG A 1 87  ? 79.41214  -23.28640 -43.22367 1.000 48.67119  ? 87  ARG A N   1 
ATOM   652  C  CA  . ARG A 1 87  ? 79.98208  -24.16181 -42.20062 1.000 47.06940  ? 87  ARG A CA  1 
ATOM   653  C  C   . ARG A 1 87  ? 79.11272  -24.19161 -40.94728 1.000 45.88201  ? 87  ARG A C   1 
ATOM   654  O  O   . ARG A 1 87  ? 78.89639  -25.25667 -40.35774 1.000 44.87866  ? 87  ARG A O   1 
ATOM   655  C  CB  . ARG A 1 87  ? 81.40542  -23.72150 -41.85493 1.000 43.13139  ? 87  ARG A CB  1 
ATOM   656  C  CG  . ARG A 1 87  ? 82.01023  -24.49592 -40.69064 1.000 49.55599  ? 87  ARG A CG  1 
ATOM   657  C  CD  . ARG A 1 87  ? 83.39141  -23.98487 -40.30486 1.000 47.75041  ? 87  ARG A CD  1 
ATOM   658  N  NE  . ARG A 1 87  ? 84.40147  -24.31002 -41.30434 1.000 50.03980  ? 87  ARG A NE  1 
ATOM   659  C  CZ  . ARG A 1 87  ? 84.88351  -23.44896 -42.18999 1.000 55.17368  ? 87  ARG A CZ  1 
ATOM   660  N  NH1 . ARG A 1 87  ? 84.47121  -22.19173 -42.22900 1.000 48.49966  ? 87  ARG A NH1 1 
ATOM   661  N  NH2 . ARG A 1 87  ? 85.80652  -23.85727 -43.05513 1.000 58.84493  ? 87  ARG A NH2 1 
ATOM   662  N  N   . GLY A 1 88  ? 78.58785  -23.03698 -40.53772 1.000 48.04336  ? 88  GLY A N   1 
ATOM   663  C  CA  . GLY A 1 88  ? 77.69849  -22.97409 -39.39052 1.000 51.98169  ? 88  GLY A CA  1 
ATOM   664  C  C   . GLY A 1 88  ? 76.34811  -23.62519 -39.60250 1.000 52.33108  ? 88  GLY A C   1 
ATOM   665  O  O   . GLY A 1 88  ? 75.58342  -23.74658 -38.63966 1.000 55.73559  ? 88  GLY A O   1 
ATOM   666  N  N   . GLU A 1 89  ? 76.03468  -24.03220 -40.83086 1.000 59.27778  ? 89  GLU A N   1 
ATOM   667  C  CA  . GLU A 1 89  ? 74.80469  -24.74681 -41.14155 1.000 61.12248  ? 89  GLU A CA  1 
ATOM   668  C  C   . GLU A 1 89  ? 75.01439  -26.25171 -41.22073 1.000 59.90861  ? 89  GLU A C   1 
ATOM   669  O  O   . GLU A 1 89  ? 74.06022  -26.98511 -41.49638 1.000 62.83237  ? 89  GLU A O   1 
ATOM   670  C  CB  . GLU A 1 89  ? 74.22053  -24.24301 -42.46766 1.000 58.65922  ? 89  GLU A CB  1 
ATOM   671  C  CG  . GLU A 1 89  ? 74.09601  -22.73025 -42.57303 1.000 59.70981  ? 89  GLU A CG  1 
ATOM   672  C  CD  . GLU A 1 89  ? 72.87823  -22.19149 -41.85239 1.000 74.37356  ? 89  GLU A CD  1 
ATOM   673  O  OE1 . GLU A 1 89  ? 71.88611  -22.93957 -41.71645 1.000 77.47310  ? 89  GLU A OE1 1 
ATOM   674  O  OE2 . GLU A 1 89  ? 72.91237  -21.01934 -41.42088 1.000 80.14415  ? 89  GLU A OE2 1 
ATOM   675  N  N   . ASN A 1 90  ? 76.23261  -26.72363 -40.98191 1.000 58.66677  ? 90  ASN A N   1 
ATOM   676  C  CA  . ASN A 1 90  ? 76.59755  -28.12429 -41.18677 1.000 59.95895  ? 90  ASN A CA  1 
ATOM   677  C  C   . ASN A 1 90  ? 77.35026  -28.63093 -39.96470 1.000 55.90860  ? 90  ASN A C   1 
ATOM   678  O  O   . ASN A 1 90  ? 78.53085  -28.26995 -39.77617 1.000 54.38368  ? 90  ASN A O   1 
ATOM   679  C  CB  . ASN A 1 90  ? 77.43591  -28.26334 -42.45569 1.000 63.12386  ? 90  ASN A CB  1 
ATOM   680  C  CG  . ASN A 1 90  ? 77.85055  -29.69438 -42.74425 1.000 62.33943  ? 90  ASN A CG  1 
ATOM   681  O  OD1 . ASN A 1 90  ? 77.50470  -30.62834 -42.01736 1.000 64.02057  ? 90  ASN A OD1 1 
ATOM   682  N  ND2 . ASN A 1 90  ? 78.59152  -29.87202 -43.82918 1.000 71.11715  ? 90  ASN A ND2 1 
ATOM   683  N  N   . PRO A 1 91  ? 76.72894  -29.46471 -39.12739 1.000 55.18933  ? 91  PRO A N   1 
ATOM   684  C  CA  . PRO A 1 91  ? 77.41700  -29.93048 -37.91249 1.000 56.73553  ? 91  PRO A CA  1 
ATOM   685  C  C   . PRO A 1 91  ? 78.68850  -30.71145 -38.18719 1.000 54.73503  ? 91  PRO A C   1 
ATOM   686  O  O   . PRO A 1 91  ? 79.64149  -30.60969 -37.40548 1.000 57.10250  ? 91  PRO A O   1 
ATOM   687  C  CB  . PRO A 1 91  ? 76.35516  -30.79989 -37.22218 1.000 59.54054  ? 91  PRO A CB  1 
ATOM   688  C  CG  . PRO A 1 91  ? 75.38219  -31.15281 -38.29596 1.000 62.36725  ? 91  PRO A CG  1 
ATOM   689  C  CD  . PRO A 1 91  ? 75.35272  -29.97580 -39.21503 1.000 62.60984  ? 91  PRO A CD  1 
ATOM   690  N  N   . GLU A 1 92  ? 78.74202  -31.48153 -39.27506 1.000 54.35745  ? 92  GLU A N   1 
ATOM   691  C  CA  . GLU A 1 92  ? 79.94378  -32.25934 -39.56033 1.000 54.25602  ? 92  GLU A CA  1 
ATOM   692  C  C   . GLU A 1 92  ? 81.11337  -31.35585 -39.93696 1.000 49.12218  ? 92  GLU A C   1 
ATOM   693  O  O   . GLU A 1 92  ? 82.25824  -31.61913 -39.55010 1.000 51.53436  ? 92  GLU A O   1 
ATOM   694  C  CB  . GLU A 1 92  ? 79.66166  -33.27384 -40.66962 1.000 59.85526  ? 92  GLU A CB  1 
ATOM   695  C  CG  . GLU A 1 92  ? 80.82562  -34.20504 -40.96914 1.000 62.28315  ? 92  GLU A CG  1 
ATOM   696  N  N   . ASP A 1 93  ? 80.84934  -30.28861 -40.69458 1.000 50.39417  ? 93  ASP A N   1 
ATOM   697  C  CA  . ASP A 1 93  ? 81.91336  -29.34936 -41.03459 1.000 49.49230  ? 93  ASP A CA  1 
ATOM   698  C  C   . ASP A 1 93  ? 82.25488  -28.43778 -39.86225 1.000 48.37480  ? 93  ASP A C   1 
ATOM   699  O  O   . ASP A 1 93  ? 83.41618  -28.04478 -39.70270 1.000 48.88137  ? 93  ASP A O   1 
ATOM   700  C  CB  . ASP A 1 93  ? 81.51622  -28.52503 -42.25679 1.000 56.41639  ? 93  ASP A CB  1 
ATOM   701  C  CG  . ASP A 1 93  ? 81.57324  -29.32896 -43.54226 1.000 72.71838  ? 93  ASP A CG  1 
ATOM   702  O  OD1 . ASP A 1 93  ? 82.12134  -30.45383 -43.52186 1.000 69.96438  ? 93  ASP A OD1 1 
ATOM   703  O  OD2 . ASP A 1 93  ? 81.06263  -28.84097 -44.57357 1.000 73.70379  ? 93  ASP A OD2 1 
ATOM   704  N  N   . THR A 1 94  ? 81.26755  -28.09302 -39.03460 1.000 41.10990  ? 94  THR A N   1 
ATOM   705  C  CA  . THR A 1 94  ? 81.56128  -27.36008 -37.80702 1.000 47.85096  ? 94  THR A CA  1 
ATOM   706  C  C   . THR A 1 94  ? 82.44910  -28.18144 -36.88198 1.000 42.76363  ? 94  THR A C   1 
ATOM   707  O  O   . THR A 1 94  ? 83.48750  -27.70351 -36.41013 1.000 46.37982  ? 94  THR A O   1 
ATOM   708  C  CB  . THR A 1 94  ? 80.26431  -26.97940 -37.09743 1.000 42.32034  ? 94  THR A CB  1 
ATOM   709  O  OG1 . THR A 1 94  ? 79.61649  -25.92918 -37.82230 1.000 41.85264  ? 94  THR A OG1 1 
ATOM   710  C  CG2 . THR A 1 94  ? 80.55314  -26.51451 -35.67480 1.000 47.64792  ? 94  THR A CG2 1 
ATOM   711  N  N   . LYS A 1 95  ? 82.05562  -29.43111 -36.61837 1.000 48.18914  ? 95  LYS A N   1 
ATOM   712  C  CA  . LYS A 1 95  ? 82.83539  -30.28284 -35.72551 1.000 46.06084  ? 95  LYS A CA  1 
ATOM   713  C  C   . LYS A 1 95  ? 84.23733  -30.52554 -36.26759 1.000 48.00073  ? 95  LYS A C   1 
ATOM   714  O  O   . LYS A 1 95  ? 85.19717  -30.63182 -35.49538 1.000 45.25039  ? 95  LYS A O   1 
ATOM   715  C  CB  . LYS A 1 95  ? 82.11695  -31.61138 -35.49910 1.000 51.29809  ? 95  LYS A CB  1 
ATOM   716  C  CG  . LYS A 1 95  ? 82.81411  -32.50477 -34.48720 1.000 55.76889  ? 95  LYS A CG  1 
ATOM   717  C  CD  . LYS A 1 95  ? 81.91818  -33.64527 -34.02834 1.000 61.79225  ? 95  LYS A CD  1 
ATOM   718  C  CE  . LYS A 1 95  ? 82.41905  -34.24253 -32.72197 1.000 53.42691  ? 95  LYS A CE  1 
ATOM   719  N  NZ  . LYS A 1 95  ? 83.83669  -34.68024 -32.82262 1.000 64.96154  ? 95  LYS A NZ  1 
ATOM   720  N  N   . GLN A 1 96  ? 84.37714  -30.61232 -37.59335 1.000 41.42515  ? 96  GLN A N   1 
ATOM   721  C  CA  . GLN A 1 96  ? 85.69336  -30.83704 -38.18485 1.000 46.75626  ? 96  GLN A CA  1 
ATOM   722  C  C   . GLN A 1 96  ? 86.65198  -29.70033 -37.85590 1.000 46.47503  ? 96  GLN A C   1 
ATOM   723  O  O   . GLN A 1 96  ? 87.85054  -29.92755 -37.65179 1.000 47.18402  ? 96  GLN A O   1 
ATOM   724  C  CB  . GLN A 1 96  ? 85.57405  -31.00167 -39.69985 1.000 56.22391  ? 96  GLN A CB  1 
ATOM   725  C  CG  . GLN A 1 96  ? 86.90939  -31.19877 -40.39409 1.000 58.98658  ? 96  GLN A CG  1 
ATOM   726  C  CD  . GLN A 1 96  ? 86.80431  -31.13408 -41.90359 1.000 76.90854  ? 96  GLN A CD  1 
ATOM   727  O  OE1 . GLN A 1 96  ? 85.94870  -30.43773 -42.44966 1.000 83.05462  ? 96  GLN A OE1 1 
ATOM   728  N  NE2 . GLN A 1 96  ? 87.67669  -31.86553 -42.58825 1.000 83.71626  ? 96  GLN A NE2 1 
ATOM   729  N  N   . LEU A 1 97  ? 86.14790  -28.46725 -37.80736 1.000 45.05573  ? 97  LEU A N   1 
ATOM   730  C  CA  . LEU A 1 97  ? 87.00767  -27.34670 -37.44422 1.000 46.45055  ? 97  LEU A CA  1 
ATOM   731  C  C   . LEU A 1 97  ? 87.22040  -27.27849 -35.93576 1.000 41.95135  ? 97  LEU A C   1 
ATOM   732  O  O   . LEU A 1 97  ? 88.35322  -27.10764 -35.47088 1.000 44.04484  ? 97  LEU A O   1 
ATOM   733  C  CB  . LEU A 1 97  ? 86.42070  -26.03385 -37.96802 1.000 42.02693  ? 97  LEU A CB  1 
ATOM   734  C  CG  . LEU A 1 97  ? 87.26129  -24.77857 -37.71029 1.000 43.71362  ? 97  LEU A CG  1 
ATOM   735  C  CD1 . LEU A 1 97  ? 88.71168  -25.00324 -38.11105 1.000 35.50907  ? 97  LEU A CD1 1 
ATOM   736  C  CD2 . LEU A 1 97  ? 86.68137  -23.57886 -38.44780 1.000 40.28811  ? 97  LEU A CD2 1 
ATOM   737  N  N   . THR A 1 98  ? 86.14343  -27.40807 -35.15529 1.000 37.35968  ? 98  THR A N   1 
ATOM   738  C  CA  . THR A 1 98  ? 86.27831  -27.31775 -33.70315 1.000 46.40961  ? 98  THR A CA  1 
ATOM   739  C  C   . THR A 1 98  ? 87.18664  -28.41486 -33.16234 1.000 45.25851  ? 98  THR A C   1 
ATOM   740  O  O   . THR A 1 98  ? 87.93788  -28.18996 -32.20670 1.000 43.72581  ? 98  THR A O   1 
ATOM   741  C  CB  . THR A 1 98  ? 84.90714  -27.38358 -33.02963 1.000 40.77984  ? 98  THR A CB  1 
ATOM   742  O  OG1 . THR A 1 98  ? 84.26166  -28.61591 -33.36688 1.000 49.06430  ? 98  THR A OG1 1 
ATOM   743  C  CG2 . THR A 1 98  ? 84.03481  -26.22643 -33.47184 1.000 39.20490  ? 98  THR A CG2 1 
ATOM   744  N  N   . ASP A 1 99  ? 87.14266  -29.60549 -33.76926 1.000 46.90814  ? 99  ASP A N   1 
ATOM   745  C  CA  . ASP A 1 99  ? 88.02352  -30.68695 -33.33689 1.000 46.84727  ? 99  ASP A CA  1 
ATOM   746  C  C   . ASP A 1 99  ? 89.48655  -30.33347 -33.56414 1.000 43.90890  ? 99  ASP A C   1 
ATOM   747  O  O   . ASP A 1 99  ? 90.34611  -30.66727 -32.74158 1.000 41.61979  ? 99  ASP A O   1 
ATOM   748  C  CB  . ASP A 1 99  ? 87.67305  -31.98409 -34.06633 1.000 51.11974  ? 99  ASP A CB  1 
ATOM   749  C  CG  . ASP A 1 99  ? 86.43553  -32.65795 -33.50200 1.000 58.68380  ? 99  ASP A CG  1 
ATOM   750  O  OD1 . ASP A 1 99  ? 85.95668  -32.23302 -32.42713 1.000 52.51837  ? 99  ASP A OD1 1 
ATOM   751  O  OD2 . ASP A 1 99  ? 85.93947  -33.61502 -34.13726 1.000 62.19743  ? 99  ASP A OD2 1 
ATOM   752  N  N   . GLN A 1 100 ? 89.79126  -29.65819 -34.67607 1.000 40.69506  ? 100 GLN A N   1 
ATOM   753  C  CA  . GLN A 1 100 ? 91.17714  -29.29813 -34.95906 1.000 43.33519  ? 100 GLN A CA  1 
ATOM   754  C  C   . GLN A 1 100 ? 91.67810  -28.19811 -34.03416 1.000 41.88959  ? 100 GLN A C   1 
ATOM   755  O  O   . GLN A 1 100 ? 92.87508  -28.14509 -33.72995 1.000 41.91942  ? 100 GLN A O   1 
ATOM   756  C  CB  . GLN A 1 100 ? 91.32494  -28.86387 -36.41514 1.000 47.90368  ? 100 GLN A CB  1 
ATOM   757  C  CG  . GLN A 1 100 ? 91.05799  -29.96490 -37.42159 1.000 51.35840  ? 100 GLN A CG  1 
ATOM   758  C  CD  . GLN A 1 100 ? 91.30170  -29.51160 -38.83991 1.000 52.36027  ? 100 GLN A CD  1 
ATOM   759  O  OE1 . GLN A 1 100 ? 92.44083  -29.48918 -39.30866 1.000 60.11958  ? 100 GLN A OE1 1 
ATOM   760  N  NE2 . GLN A 1 100 ? 90.23227  -29.13735 -39.53335 1.000 56.83924  ? 100 GLN A NE2 1 
ATOM   761  N  N   . VAL A 1 101 ? 90.79355  -27.30401 -33.59727 1.000 37.94635  ? 101 VAL A N   1 
ATOM   762  C  CA  . VAL A 1 101 ? 91.19007  -26.28162 -32.63591 1.000 45.64590  ? 101 VAL A CA  1 
ATOM   763  C  C   . VAL A 1 101 ? 91.31076  -26.88176 -31.24163 1.000 39.11159  ? 101 VAL A C   1 
ATOM   764  O  O   . VAL A 1 101 ? 92.33277  -26.71745 -30.56630 1.000 38.64840  ? 101 VAL A O   1 
ATOM   765  C  CB  . VAL A 1 101 ? 90.19501  -25.10510 -32.66201 1.000 41.17867  ? 101 VAL A CB  1 
ATOM   766  C  CG1 . VAL A 1 101 ? 90.56479  -24.07463 -31.59862 1.000 38.50197  ? 101 VAL A CG1 1 
ATOM   767  C  CG2 . VAL A 1 101 ? 90.15748  -24.46702 -34.04775 1.000 39.08809  ? 101 VAL A CG2 1 
ATOM   768  N  N   . ALA A 1 102 ? 90.27507  -27.60343 -30.80172 1.000 38.01547  ? 102 ALA A N   1 
ATOM   769  C  CA  . ALA A 1 102 ? 90.26512  -28.18276 -29.46191 1.000 43.55136  ? 102 ALA A CA  1 
ATOM   770  C  C   . ALA A 1 102 ? 91.43010  -29.13376 -29.22550 1.000 44.54667  ? 102 ALA A C   1 
ATOM   771  O  O   . ALA A 1 102 ? 91.81855  -29.34009 -28.07102 1.000 45.04427  ? 102 ALA A O   1 
ATOM   772  C  CB  . ALA A 1 102 ? 88.94332  -28.91220 -29.21254 1.000 41.66324  ? 102 ALA A CB  1 
ATOM   773  N  N   . ALA A 1 103 ? 92.00229  -29.70720 -30.28798 1.000 41.82750  ? 103 ALA A N   1 
ATOM   774  C  CA  . ALA A 1 103 ? 93.14675  -30.59777 -30.13262 1.000 46.29009  ? 103 ALA A CA  1 
ATOM   775  C  C   . ALA A 1 103 ? 94.33877  -29.90269 -29.48690 1.000 47.07023  ? 103 ALA A C   1 
ATOM   776  O  O   . ALA A 1 103 ? 95.19835  -30.57792 -28.90983 1.000 48.47497  ? 103 ALA A O   1 
ATOM   777  C  CB  . ALA A 1 103 ? 93.54683  -31.17627 -31.49173 1.000 43.99949  ? 103 ALA A CB  1 
ATOM   778  N  N   . ALA A 1 104 ? 94.40941  -28.57101 -29.56776 1.000 46.71924  ? 104 ALA A N   1 
ATOM   779  C  CA  . ALA A 1 104 ? 95.49986  -27.84420 -28.92537 1.000 44.14683  ? 104 ALA A CA  1 
ATOM   780  C  C   . ALA A 1 104 ? 95.46979  -28.00617 -27.41057 1.000 40.66970  ? 104 ALA A C   1 
ATOM   781  O  O   . ALA A 1 104 ? 96.50945  -27.88499 -26.75132 1.000 44.41314  ? 104 ALA A O   1 
ATOM   782  C  CB  . ALA A 1 104 ? 95.43543  -26.36409 -29.30231 1.000 41.87624  ? 104 ALA A CB  1 
ATOM   783  N  N   . LEU A 1 105 ? 94.29253  -28.27567 -26.84100 1.000 41.45733  ? 105 LEU A N   1 
ATOM   784  C  CA  . LEU A 1 105 ? 94.19831  -28.48916 -25.40037 1.000 45.25475  ? 105 LEU A CA  1 
ATOM   785  C  C   . LEU A 1 105 ? 94.93091  -29.75277 -24.96806 1.000 51.19929  ? 105 LEU A C   1 
ATOM   786  O  O   . LEU A 1 105 ? 95.36786  -29.85290 -23.81614 1.000 58.19444  ? 105 LEU A O   1 
ATOM   787  C  CB  . LEU A 1 105 ? 92.73108  -28.56355 -24.97781 1.000 40.16604  ? 105 LEU A CB  1 
ATOM   788  C  CG  . LEU A 1 105 ? 91.85736  -27.35286 -25.30822 1.000 40.32952  ? 105 LEU A CG  1 
ATOM   789  C  CD1 . LEU A 1 105 ? 90.39756  -27.64485 -25.00532 1.000 38.02778  ? 105 LEU A CD1 1 
ATOM   790  C  CD2 . LEU A 1 105 ? 92.33422  -26.13070 -24.53772 1.000 40.19456  ? 105 LEU A CD2 1 
ATOM   791  N  N   . ASP A 1 106 ? 95.08417  -30.71901 -25.87390 1.000 51.63396  ? 106 ASP A N   1 
ATOM   792  C  CA  . ASP A 1 106 ? 95.63013  -32.02472 -25.53093 1.000 59.03964  ? 106 ASP A CA  1 
ATOM   793  C  C   . ASP A 1 106 ? 97.11500  -32.16928 -25.83497 1.000 58.70537  ? 106 ASP A C   1 
ATOM   794  O  O   . ASP A 1 106 ? 97.76123  -33.05417 -25.26358 1.000 62.61042  ? 106 ASP A O   1 
ATOM   795  C  CB  . ASP A 1 106 ? 94.85655  -33.12308 -26.27023 1.000 53.59014  ? 106 ASP A CB  1 
ATOM   796  C  CG  . ASP A 1 106 ? 93.35389  -32.99223 -26.09524 1.000 59.54387  ? 106 ASP A CG  1 
ATOM   797  O  OD1 . ASP A 1 106 ? 92.90933  -32.68312 -24.96900 1.000 62.11802  ? 106 ASP A OD1 1 
ATOM   798  O  OD2 . ASP A 1 106 ? 92.61766  -33.18665 -27.08585 1.000 61.07393  ? 106 ASP A OD2 1 
ATOM   799  N  N   . GLY A 1 107 ? 97.67044  -31.33418 -26.70758 1.000 53.32149  ? 107 GLY A N   1 
ATOM   800  C  CA  . GLY A 1 107 ? 99.07017  -31.41792 -27.04571 1.000 54.84178  ? 107 GLY A CA  1 
ATOM   801  C  C   . GLY A 1 107 ? 99.42334  -30.57497 -28.25251 1.000 57.38547  ? 107 GLY A C   1 
ATOM   802  O  O   . GLY A 1 107 ? 98.63540  -29.74032 -28.70756 1.000 52.54948  ? 107 GLY A O   1 
ATOM   803  N  N   . PRO A 1 108 ? 100.62305 -30.78031 -28.79551 1.000 57.32405  ? 108 PRO A N   1 
ATOM   804  C  CA  . PRO A 1 108 ? 101.05407 -29.98416 -29.94947 1.000 52.62773  ? 108 PRO A CA  1 
ATOM   805  C  C   . PRO A 1 108 ? 100.17063 -30.24076 -31.16015 1.000 50.92488  ? 108 PRO A C   1 
ATOM   806  O  O   . PRO A 1 108 ? 99.63145  -31.33377 -31.34437 1.000 54.57134  ? 108 PRO A O   1 
ATOM   807  C  CB  . PRO A 1 108 ? 102.49144 -30.46142 -30.19862 1.000 54.14275  ? 108 PRO A CB  1 
ATOM   808  C  CG  . PRO A 1 108 ? 102.90175 -31.17286 -28.94272 1.000 55.08938  ? 108 PRO A CG  1 
ATOM   809  C  CD  . PRO A 1 108 ? 101.64724 -31.74983 -28.37436 1.000 55.31293  ? 108 PRO A CD  1 
ATOM   810  N  N   . LEU A 1 109 ? 100.01330 -29.19547 -31.99293 1.000 51.86600  ? 109 LEU A N   1 
ATOM   811  C  CA  . LEU A 1 109 ? 99.27632  -29.36065 -33.23559 1.000 48.73675  ? 109 LEU A CA  1 
ATOM   812  C  C   . LEU A 1 109 ? 100.21852 -29.76911 -34.36241 1.000 48.82382  ? 109 LEU A C   1 
ATOM   813  O  O   . LEU A 1 109 ? 101.39592 -29.39486 -34.36124 1.000 47.92262  ? 109 LEU A O   1 
ATOM   814  C  CB  . LEU A 1 109 ? 98.57493  -28.06064 -33.62617 1.000 48.31849  ? 109 LEU A CB  1 
ATOM   815  C  CG  . LEU A 1 109 ? 97.45847  -27.48596 -32.75418 1.000 51.10950  ? 109 LEU A CG  1 
ATOM   816  C  CD1 . LEU A 1 109 ? 96.85609  -26.27488 -33.44864 1.000 41.19255  ? 109 LEU A CD1 1 
ATOM   817  C  CD2 . LEU A 1 109 ? 96.39018  -28.52544 -32.45860 1.000 45.04634  ? 109 LEU A CD2 1 
ATOM   818  N  N   . PRO A 1 110 ? 99.73091  -30.52825 -35.34290 1.000 47.62600  ? 110 PRO A N   1 
ATOM   819  C  CA  . PRO A 1 110 ? 100.51152 -30.71772 -36.56917 1.000 52.80774  ? 110 PRO A CA  1 
ATOM   820  C  C   . PRO A 1 110 ? 100.65202 -29.39714 -37.30987 1.000 52.27378  ? 110 PRO A C   1 
ATOM   821  O  O   . PRO A 1 110 ? 99.78716  -28.52229 -37.22928 1.000 51.70160  ? 110 PRO A O   1 
ATOM   822  C  CB  . PRO A 1 110 ? 99.68177  -31.72747 -37.37025 1.000 50.66203  ? 110 PRO A CB  1 
ATOM   823  C  CG  . PRO A 1 110 ? 98.28678  -31.54838 -36.86547 1.000 55.74798  ? 110 PRO A CG  1 
ATOM   824  C  CD  . PRO A 1 110 ? 98.42688  -31.21131 -35.40274 1.000 48.35104  ? 110 PRO A CD  1 
ATOM   825  N  N   . ASP A 1 111 ? 101.76486 -29.25396 -38.03415 1.000 53.53552  ? 111 ASP A N   1 
ATOM   826  C  CA  . ASP A 1 111 ? 102.00517 -28.02432 -38.78343 1.000 59.76394  ? 111 ASP A CA  1 
ATOM   827  C  C   . ASP A 1 111 ? 100.91443 -27.74505 -39.80868 1.000 50.78457  ? 111 ASP A C   1 
ATOM   828  O  O   . ASP A 1 111 ? 100.72105 -26.58600 -40.19076 1.000 56.41300  ? 111 ASP A O   1 
ATOM   829  C  CB  . ASP A 1 111 ? 103.36688 -28.08326 -39.47813 1.000 63.33324  ? 111 ASP A CB  1 
ATOM   830  C  CG  . ASP A 1 111 ? 104.52303 -27.90501 -38.51226 1.000 74.82900  ? 111 ASP A CG  1 
ATOM   831  O  OD1 . ASP A 1 111 ? 104.26940 -27.72542 -37.30166 1.000 74.88053  ? 111 ASP A OD1 1 
ATOM   832  O  OD2 . ASP A 1 111 ? 105.68674 -27.94000 -38.96657 1.000 74.08510  ? 111 ASP A OD2 1 
ATOM   833  N  N   . THR A 1 112 ? 100.19065 -28.77103 -40.24722 1.000 53.41857  ? 112 THR A N   1 
ATOM   834  C  CA  . THR A 1 112 ? 99.13383  -28.60473 -41.23424 1.000 56.95882  ? 112 THR A CA  1 
ATOM   835  C  C   . THR A 1 112 ? 97.81494  -28.13684 -40.63305 1.000 52.93847  ? 112 THR A C   1 
ATOM   836  O  O   . THR A 1 112 ? 96.84680  -27.96866 -41.38024 1.000 52.16893  ? 112 THR A O   1 
ATOM   837  C  CB  . THR A 1 112 ? 98.91161  -29.91766 -41.98765 1.000 60.80899  ? 112 THR A CB  1 
ATOM   838  O  OG1 . THR A 1 112 ? 98.69847  -30.97687 -41.04573 1.000 55.22208  ? 112 THR A OG1 1 
ATOM   839  C  CG2 . THR A 1 112 ? 100.11778 -30.24423 -42.86741 1.000 54.98074  ? 112 THR A CG2 1 
ATOM   840  N  N   . ALA A 1 113 ? 97.74462  -27.93300 -39.31897 1.000 47.46908  ? 113 ALA A N   1 
ATOM   841  C  CA  . ALA A 1 113 ? 96.52352  -27.42190 -38.71677 1.000 49.65980  ? 113 ALA A CA  1 
ATOM   842  C  C   . ALA A 1 113 ? 96.20617  -26.03446 -39.27712 1.000 40.48613  ? 113 ALA A C   1 
ATOM   843  O  O   . ALA A 1 113 ? 97.11603  -25.27374 -39.61832 1.000 39.17828  ? 113 ALA A O   1 
ATOM   844  C  CB  . ALA A 1 113 ? 96.66005  -27.35999 -37.19534 1.000 45.82069  ? 113 ALA A CB  1 
ATOM   845  N  N   . PRO A 1 114 ? 94.92803  -25.67890 -39.38277 1.000 37.77880  ? 114 PRO A N   1 
ATOM   846  C  CA  . PRO A 1 114 ? 94.56088  -24.37548 -39.95273 1.000 45.73732  ? 114 PRO A CA  1 
ATOM   847  C  C   . PRO A 1 114 ? 95.05841  -23.23475 -39.08317 1.000 45.59379  ? 114 PRO A C   1 
ATOM   848  O  O   . PRO A 1 114 ? 95.28689  -23.41693 -37.87789 1.000 45.46035  ? 114 PRO A O   1 
ATOM   849  C  CB  . PRO A 1 114 ? 93.02575  -24.42255 -39.98902 1.000 42.57603  ? 114 PRO A CB  1 
ATOM   850  C  CG  . PRO A 1 114 ? 92.65180  -25.44313 -38.97695 1.000 47.56393  ? 114 PRO A CG  1 
ATOM   851  C  CD  . PRO A 1 114 ? 93.74293  -26.46764 -39.00591 1.000 42.56296  ? 114 PRO A CD  1 
ATOM   852  N  N   . PRO A 1 115 ? 95.24362  -22.04308 -39.66389 1.000 46.93158  ? 115 PRO A N   1 
ATOM   853  C  CA  . PRO A 1 115 ? 95.78305  -20.91552 -38.88100 1.000 42.65961  ? 115 PRO A CA  1 
ATOM   854  C  C   . PRO A 1 115 ? 94.98393  -20.59289 -37.63010 1.000 36.81063  ? 115 PRO A C   1 
ATOM   855  O  O   . PRO A 1 115 ? 95.57253  -20.23128 -36.60448 1.000 40.75952  ? 115 PRO A O   1 
ATOM   856  C  CB  . PRO A 1 115 ? 95.75020  -19.75392 -39.88551 1.000 42.42393  ? 115 PRO A CB  1 
ATOM   857  C  CG  . PRO A 1 115 ? 95.83679  -20.41010 -41.22004 1.000 45.96796  ? 115 PRO A CG  1 
ATOM   858  C  CD  . PRO A 1 115 ? 95.07940  -21.70308 -41.08737 1.000 45.15516  ? 115 PRO A CD  1 
ATOM   859  N  N   . ILE A 1 116 ? 93.65550  -20.71528 -37.68365 1.000 36.74810  ? 116 ILE A N   1 
ATOM   860  C  CA  . ILE A 1 116 ? 92.83672  -20.39017 -36.52036 1.000 36.16285  ? 116 ILE A CA  1 
ATOM   861  C  C   . ILE A 1 116 ? 93.12422  -21.34889 -35.37155 1.000 41.88923  ? 116 ILE A C   1 
ATOM   862  O  O   . ILE A 1 116 ? 92.93419  -21.00004 -34.20054 1.000 38.66950  ? 116 ILE A O   1 
ATOM   863  C  CB  . ILE A 1 116 ? 91.34249  -20.38824 -36.90157 1.000 37.32825  ? 116 ILE A CB  1 
ATOM   864  C  CG1 . ILE A 1 116 ? 90.51594  -19.67696 -35.82700 1.000 42.73941  ? 116 ILE A CG1 1 
ATOM   865  C  CG2 . ILE A 1 116 ? 90.83222  -21.81274 -37.12476 1.000 34.76432  ? 116 ILE A CG2 1 
ATOM   866  C  CD1 . ILE A 1 116 ? 90.89593  -18.21748 -35.62541 1.000 35.83130  ? 116 ILE A CD1 1 
ATOM   867  N  N   . ALA A 1 117 ? 93.59949  -22.55998 -35.67892 1.000 39.89724  ? 117 ALA A N   1 
ATOM   868  C  CA  . ALA A 1 117 ? 93.94554  -23.51728 -34.63385 1.000 38.91052  ? 117 ALA A CA  1 
ATOM   869  C  C   . ALA A 1 117 ? 95.31516  -23.21877 -34.03871 1.000 36.47381  ? 117 ALA A C   1 
ATOM   870  O  O   . ALA A 1 117 ? 95.50096  -23.32529 -32.82152 1.000 40.96876  ? 117 ALA A O   1 
ATOM   871  C  CB  . ALA A 1 117 ? 93.89846  -24.94387 -35.18514 1.000 35.87064  ? 117 ALA A CB  1 
ATOM   872  N  N   . HIS A 1 118 ? 96.28571  -22.84890 -34.87899 1.000 35.34845  ? 118 HIS A N   1 
ATOM   873  C  CA  . HIS A 1 118 ? 97.58233  -22.42269 -34.36242 1.000 40.09829  ? 118 HIS A CA  1 
ATOM   874  C  C   . HIS A 1 118 ? 97.45689  -21.17739 -33.49489 1.000 42.56237  ? 118 HIS A C   1 
ATOM   875  O  O   . HIS A 1 118 ? 98.20285  -21.02208 -32.52004 1.000 42.02865  ? 118 HIS A O   1 
ATOM   876  C  CB  . HIS A 1 118 ? 98.55937  -22.16470 -35.51214 1.000 43.99881  ? 118 HIS A CB  1 
ATOM   877  C  CG  . HIS A 1 118 ? 99.00807  -23.40580 -36.21821 1.000 51.32958  ? 118 HIS A CG  1 
ATOM   878  N  ND1 . HIS A 1 118 ? 99.74259  -24.39353 -35.59709 1.000 42.95145  ? 118 HIS A ND1 1 
ATOM   879  C  CD2 . HIS A 1 118 ? 98.83585  -23.81388 -37.49792 1.000 45.31664  ? 118 HIS A CD2 1 
ATOM   880  C  CE1 . HIS A 1 118 ? 99.99636  -25.35966 -36.46202 1.000 51.30736  ? 118 HIS A CE1 1 
ATOM   881  N  NE2 . HIS A 1 118 ? 99.45786  -25.03234 -37.62303 1.000 49.64058  ? 118 HIS A NE2 1 
ATOM   882  N  N   . GLY A 1 119 ? 96.52784  -20.28117 -33.83175 1.000 39.65612  ? 119 GLY A N   1 
ATOM   883  C  CA  . GLY A 1 119 ? 96.33386  -19.09686 -33.01426 1.000 36.85374  ? 119 GLY A CA  1 
ATOM   884  C  C   . GLY A 1 119 ? 95.78886  -19.42763 -31.63851 1.000 40.36834  ? 119 GLY A C   1 
ATOM   885  O  O   . GLY A 1 119 ? 96.23796  -18.87085 -30.63223 1.000 37.05426  ? 119 GLY A O   1 
ATOM   886  N  N   . PHE A 1 120 ? 94.81536  -20.33931 -31.57373 1.000 40.30293  ? 120 PHE A N   1 
ATOM   887  C  CA  . PHE A 1 120 ? 94.29156  -20.75871 -30.27913 1.000 40.55702  ? 120 PHE A CA  1 
ATOM   888  C  C   . PHE A 1 120 ? 95.36490  -21.45272 -29.45112 1.000 42.68698  ? 120 PHE A C   1 
ATOM   889  O  O   . PHE A 1 120 ? 95.46655  -21.22707 -28.24046 1.000 37.53644  ? 120 PHE A O   1 
ATOM   890  C  CB  . PHE A 1 120 ? 93.08665  -21.67950 -30.45999 1.000 37.71846  ? 120 PHE A CB  1 
ATOM   891  C  CG  . PHE A 1 120 ? 92.52145  -22.18348 -29.16139 1.000 43.48677  ? 120 PHE A CG  1 
ATOM   892  C  CD1 . PHE A 1 120 ? 91.70568  -21.37287 -28.38410 1.000 40.02830  ? 120 PHE A CD1 1 
ATOM   893  C  CD2 . PHE A 1 120 ? 92.81796  -23.46100 -28.70716 1.000 42.80292  ? 120 PHE A CD2 1 
ATOM   894  C  CE1 . PHE A 1 120 ? 91.18921  -21.83132 -27.17674 1.000 40.72528  ? 120 PHE A CE1 1 
ATOM   895  C  CE2 . PHE A 1 120 ? 92.30653  -23.92598 -27.50481 1.000 39.88136  ? 120 PHE A CE2 1 
ATOM   896  C  CZ  . PHE A 1 120 ? 91.49101  -23.10999 -26.73824 1.000 42.31061  ? 120 PHE A CZ  1 
ATOM   897  N  N   . ALA A 1 121 ? 96.17529  -22.30183 -30.08857 1.000 40.33160  ? 121 ALA A N   1 
ATOM   898  C  CA  . ALA A 1 121 ? 97.23873  -22.99519 -29.37083 1.000 38.98171  ? 121 ALA A CA  1 
ATOM   899  C  C   . ALA A 1 121 ? 98.22605  -22.01977 -28.74868 1.000 39.78594  ? 121 ALA A C   1 
ATOM   900  O  O   . ALA A 1 121 ? 98.76485  -22.28703 -27.66790 1.000 40.19690  ? 121 ALA A O   1 
ATOM   901  C  CB  . ALA A 1 121 ? 97.96699  -23.95624 -30.31089 1.000 36.78812  ? 121 ALA A CB  1 
ATOM   902  N  N   . ASP A 1 122 ? 98.48135  -20.88980 -29.41216 1.000 39.94461  ? 122 ASP A N   1 
ATOM   903  C  CA  . ASP A 1 122 ? 99.39164  -19.90259 -28.84438 1.000 36.90776  ? 122 ASP A CA  1 
ATOM   904  C  C   . ASP A 1 122 ? 98.76809  -19.19424 -27.64900 1.000 39.92561  ? 122 ASP A C   1 
ATOM   905  O  O   . ASP A 1 122 ? 99.47606  -18.84976 -26.69692 1.000 40.13430  ? 122 ASP A O   1 
ATOM   906  C  CB  . ASP A 1 122 ? 99.80330  -18.88697 -29.90921 1.000 38.27251  ? 122 ASP A CB  1 
ATOM   907  C  CG  . ASP A 1 122 ? 100.87751 -17.93967 -29.42068 1.000 44.36276  ? 122 ASP A CG  1 
ATOM   908  O  OD1 . ASP A 1 122 ? 102.03065 -18.38707 -29.24541 1.000 49.36199  ? 122 ASP A OD1 1 
ATOM   909  O  OD2 . ASP A 1 122 ? 100.56930 -16.75032 -29.20347 1.000 48.53463  ? 122 ASP A OD2 1 
ATOM   910  N  N   . ILE A 1 123 ? 97.45304  -18.96870 -27.68019 1.000 39.39101  ? 123 ILE A N   1 
ATOM   911  C  CA  . ILE A 1 123 ? 96.77572  -18.34972 -26.54464 1.000 39.90608  ? 123 ILE A CA  1 
ATOM   912  C  C   . ILE A 1 123 ? 96.74296  -19.30509 -25.35965 1.000 41.37927  ? 123 ILE A C   1 
ATOM   913  O  O   . ILE A 1 123 ? 97.05184  -18.92376 -24.22464 1.000 39.32454  ? 123 ILE A O   1 
ATOM   914  C  CB  . ILE A 1 123 ? 95.35777  -17.90685 -26.94201 1.000 37.23123  ? 123 ILE A CB  1 
ATOM   915  C  CG1 . ILE A 1 123 ? 95.42454  -16.69680 -27.87003 1.000 41.60405  ? 123 ILE A CG1 1 
ATOM   916  C  CG2 . ILE A 1 123 ? 94.52345  -17.60336 -25.70274 1.000 34.26322  ? 123 ILE A CG2 1 
ATOM   917  C  CD1 . ILE A 1 123 ? 94.08457  -16.26808 -28.36338 1.000 42.47122  ? 123 ILE A CD1 1 
ATOM   918  N  N   . TRP A 1 124 ? 96.36408  -20.56198 -25.60975 1.000 37.39911  ? 124 TRP A N   1 
ATOM   919  C  CA  . TRP A 1 124 ? 96.24229  -21.53914 -24.53221 1.000 41.05806  ? 124 TRP A CA  1 
ATOM   920  C  C   . TRP A 1 124 ? 97.58088  -21.78062 -23.84865 1.000 39.90073  ? 124 TRP A C   1 
ATOM   921  O  O   . TRP A 1 124 ? 97.64705  -21.88584 -22.61791 1.000 42.28152  ? 124 TRP A O   1 
ATOM   922  C  CB  . TRP A 1 124 ? 95.67195  -22.84872 -25.07841 1.000 37.90458  ? 124 TRP A CB  1 
ATOM   923  C  CG  . TRP A 1 124 ? 95.44299  -23.89746 -24.03141 1.000 41.80790  ? 124 TRP A CG  1 
ATOM   924  C  CD1 . TRP A 1 124 ? 95.97369  -25.15437 -24.00027 1.000 43.85277  ? 124 TRP A CD1 1 
ATOM   925  C  CD2 . TRP A 1 124 ? 94.62749  -23.77775 -22.85770 1.000 40.83456  ? 124 TRP A CD2 1 
ATOM   926  N  NE1 . TRP A 1 124 ? 95.53613  -25.82627 -22.88373 1.000 45.59089  ? 124 TRP A NE1 1 
ATOM   927  C  CE2 . TRP A 1 124 ? 94.70851  -25.00386 -22.16608 1.000 44.14396  ? 124 TRP A CE2 1 
ATOM   928  C  CE3 . TRP A 1 124 ? 93.83522  -22.75447 -22.32550 1.000 43.17221  ? 124 TRP A CE3 1 
ATOM   929  C  CZ2 . TRP A 1 124 ? 94.02139  -25.23719 -20.97373 1.000 42.00855  ? 124 TRP A CZ2 1 
ATOM   930  C  CZ3 . TRP A 1 124 ? 93.16003  -22.98609 -21.13606 1.000 41.03887  ? 124 TRP A CZ3 1 
ATOM   931  C  CH2 . TRP A 1 124 ? 93.26002  -24.21666 -20.47326 1.000 38.87657  ? 124 TRP A CH2 1 
ATOM   932  N  N   . ARG A 1 125 ? 98.65961  -21.86751 -24.63166 1.000 37.39420  ? 125 ARG A N   1 
ATOM   933  C  CA  . ARG A 1 125 ? 99.98945  -22.01543 -24.05118 1.000 41.87417  ? 125 ARG A CA  1 
ATOM   934  C  C   . ARG A 1 125 ? 100.29735 -20.88047 -23.08302 1.000 48.35570  ? 125 ARG A C   1 
ATOM   935  O  O   . ARG A 1 125 ? 100.82624 -21.11111 -21.98948 1.000 45.41692  ? 125 ARG A O   1 
ATOM   936  C  CB  . ARG A 1 125 ? 101.04322 -22.06982 -25.15879 1.000 45.68774  ? 125 ARG A CB  1 
ATOM   937  C  CG  . ARG A 1 125 ? 102.47075 -22.04263 -24.64440 1.000 51.77719  ? 125 ARG A CG  1 
ATOM   938  C  CD  . ARG A 1 125 ? 103.48001 -21.92905 -25.77646 1.000 59.22419  ? 125 ARG A CD  1 
ATOM   939  N  NE  . ARG A 1 125 ? 103.31301 -20.70460 -26.55084 1.000 62.01770  ? 125 ARG A NE  1 
ATOM   940  C  CZ  . ARG A 1 125 ? 103.76669 -19.51515 -26.17737 1.000 69.47684  ? 125 ARG A CZ  1 
ATOM   941  N  NH1 . ARG A 1 125 ? 104.39847 -19.34414 -25.02722 1.000 64.97984  ? 125 ARG A NH1 1 
ATOM   942  N  NH2 . ARG A 1 125 ? 103.57966 -18.46910 -26.97597 1.000 59.41840  ? 125 ARG A NH2 1 
ATOM   943  N  N   . ARG A 1 126 ? 99.96291  -19.64457 -23.46559 1.000 43.98962  ? 126 ARG A N   1 
ATOM   944  C  CA  . ARG A 1 126 ? 100.22131 -18.50486 -22.59196 1.000 42.72541  ? 126 ARG A CA  1 
ATOM   945  C  C   . ARG A 1 126 ? 99.23865  -18.44881 -21.42929 1.000 38.74147  ? 126 ARG A C   1 
ATOM   946  O  O   . ARG A 1 126 ? 99.57459  -17.92612 -20.36053 1.000 37.60786  ? 126 ARG A O   1 
ATOM   947  C  CB  . ARG A 1 126 ? 100.16613 -17.20429 -23.39222 1.000 36.96942  ? 126 ARG A CB  1 
ATOM   948  C  CG  . ARG A 1 126 ? 101.42154 -16.91361 -24.19555 1.000 43.20695  ? 126 ARG A CG  1 
ATOM   949  C  CD  . ARG A 1 126 ? 101.30185 -15.57204 -24.90691 1.000 46.35580  ? 126 ARG A CD  1 
ATOM   950  N  NE  . ARG A 1 126 ? 100.33100 -15.61894 -25.99407 1.000 41.49319  ? 126 ARG A NE  1 
ATOM   951  C  CZ  . ARG A 1 126 ? 99.72687  -14.55471 -26.50674 1.000 45.46822  ? 126 ARG A CZ  1 
ATOM   952  N  NH1 . ARG A 1 126 ? 99.93091  -13.34080 -26.02020 1.000 35.99132  ? 126 ARG A NH1 1 
ATOM   953  N  NH2 . ARG A 1 126 ? 98.89269  -14.71238 -27.53034 1.000 35.73548  ? 126 ARG A NH2 1 
ATOM   954  N  N   . THR A 1 127 ? 98.02546  -18.97176 -21.61740 1.000 35.15801  ? 127 THR A N   1 
ATOM   955  C  CA  . THR A 1 127 ? 97.03378  -18.94458 -20.54757 1.000 39.84841  ? 127 THR A CA  1 
ATOM   956  C  C   . THR A 1 127 ? 97.43973  -19.84037 -19.38200 1.000 41.69254  ? 127 THR A C   1 
ATOM   957  O  O   . THR A 1 127 ? 97.25906  -19.47148 -18.21643 1.000 38.84357  ? 127 THR A O   1 
ATOM   958  C  CB  . THR A 1 127 ? 95.66882  -19.36743 -21.08838 1.000 40.23094  ? 127 THR A CB  1 
ATOM   959  O  OG1 . THR A 1 127 ? 95.26718  -18.46868 -22.12962 1.000 40.04655  ? 127 THR A OG1 1 
ATOM   960  C  CG2 . THR A 1 127 ? 94.62761  -19.34466 -19.98044 1.000 39.74927  ? 127 THR A CG2 1 
ATOM   961  N  N   . CYS A 1 128 ? 98.00448  -21.01130 -19.67551 1.000 41.64738  ? 128 CYS A N   1 
ATOM   962  C  CA  . CYS A 1 128 ? 98.25405  -22.00949 -18.64153 1.000 41.21448  ? 128 CYS A CA  1 
ATOM   963  C  C   . CYS A 1 128 ? 99.57987  -21.82461 -17.92783 1.000 40.31285  ? 128 CYS A C   1 
ATOM   964  O  O   . CYS A 1 128 ? 99.70021  -22.22026 -16.76280 1.000 45.62788  ? 128 CYS A O   1 
ATOM   965  C  CB  . CYS A 1 128 ? 98.21699  -23.40395 -19.24520 1.000 52.00688  ? 128 CYS A CB  1 
ATOM   966  S  SG  . CYS A 1 128 ? 96.56949  -23.91207 -19.60011 1.000 68.22594  ? 128 CYS A SG  1 
ATOM   967  N  N   . GLU A 1 129 ? 100.58240 -21.27590 -18.60908 1.000 43.52447  ? 129 GLU A N   1 
ATOM   968  C  CA  . GLU A 1 129 ? 101.90724 -21.13725 -18.01960 1.000 44.53334  ? 129 GLU A CA  1 
ATOM   969  C  C   . GLU A 1 129 ? 101.83252 -20.34150 -16.72731 1.000 45.28477  ? 129 GLU A C   1 
ATOM   970  O  O   . GLU A 1 129 ? 101.41086 -19.18144 -16.72276 1.000 46.63374  ? 129 GLU A O   1 
ATOM   971  C  CB  . GLU A 1 129 ? 102.86300 -20.46404 -19.00385 1.000 49.12000  ? 129 GLU A CB  1 
ATOM   972  C  CG  . GLU A 1 129 ? 103.57720 -21.43485 -19.92229 1.000 58.47513  ? 129 GLU A CG  1 
ATOM   973  C  CD  . GLU A 1 129 ? 104.35184 -20.73334 -21.02160 1.000 73.64539  ? 129 GLU A CD  1 
ATOM   974  O  OE1 . GLU A 1 129 ? 104.43367 -19.48390 -20.99269 1.000 68.69340  ? 129 GLU A OE1 1 
ATOM   975  O  OE2 . GLU A 1 129 ? 104.87210 -21.43272 -21.91827 1.000 62.60160  ? 129 GLU A OE2 1 
ATOM   976  N  N   . GLY A 1 130 ? 102.22710 -20.97479 -15.62793 1.000 42.16163  ? 130 GLY A N   1 
ATOM   977  C  CA  . GLY A 1 130 ? 102.27951 -20.30728 -14.34875 1.000 44.08161  ? 130 GLY A CA  1 
ATOM   978  C  C   . GLY A 1 130 ? 101.04011 -20.44585 -13.49610 1.000 43.80375  ? 130 GLY A C   1 
ATOM   979  O  O   . GLY A 1 130 ? 101.02311 -19.92407 -12.37570 1.000 46.76506  ? 130 GLY A O   1 
ATOM   980  N  N   . MET A 1 131 ? 100.00139 -21.11393 -13.98497 1.000 38.47949  ? 131 MET A N   1 
ATOM   981  C  CA  . MET A 1 131 ? 98.82998  -21.42610 -13.17993 1.000 45.35573  ? 131 MET A CA  1 
ATOM   982  C  C   . MET A 1 131 ? 98.94793  -22.84989 -12.63899 1.000 44.24945  ? 131 MET A C   1 
ATOM   983  O  O   . MET A 1 131 ? 99.77342  -23.64361 -13.09481 1.000 39.43867  ? 131 MET A O   1 
ATOM   984  C  CB  . MET A 1 131 ? 97.55013  -21.25592 -14.00520 1.000 38.45179  ? 131 MET A CB  1 
ATOM   985  C  CG  . MET A 1 131 ? 97.49535  -19.94454 -14.80048 1.000 35.37496  ? 131 MET A CG  1 
ATOM   986  S  SD  . MET A 1 131 ? 97.35884  -18.45904 -13.77061 1.000 36.72947  ? 131 MET A SD  1 
ATOM   987  C  CE  . MET A 1 131 ? 95.63350  -18.50855 -13.31273 1.000 30.61270  ? 131 MET A CE  1 
ATOM   988  N  N   . THR A 1 132 ? 98.12324  -23.16880 -11.64095 1.000 37.34643  ? 132 THR A N   1 
ATOM   989  C  CA  . THR A 1 132 ? 98.14763  -24.52076 -11.10259 1.000 41.37721  ? 132 THR A CA  1 
ATOM   990  C  C   . THR A 1 132 ? 97.63604  -25.50781 -12.15442 1.000 43.72985  ? 132 THR A C   1 
ATOM   991  O  O   . THR A 1 132 ? 96.81429  -25.15112 -13.00434 1.000 41.04543  ? 132 THR A O   1 
ATOM   992  C  CB  . THR A 1 132 ? 97.31423  -24.63299 -9.81905  1.000 40.41858  ? 132 THR A CB  1 
ATOM   993  O  OG1 . THR A 1 132 ? 95.92907  -24.40649 -10.09957 1.000 36.81840  ? 132 THR A OG1 1 
ATOM   994  C  CG2 . THR A 1 132 ? 97.78242  -23.62589 -8.77038  1.000 38.81677  ? 132 THR A CG2 1 
ATOM   995  N  N   . PRO A 1 133 ? 98.14327  -26.74570 -12.14343 1.000 42.34328  ? 133 PRO A N   1 
ATOM   996  C  CA  . PRO A 1 133 ? 97.62944  -27.75331 -13.08860 1.000 40.77756  ? 133 PRO A CA  1 
ATOM   997  C  C   . PRO A 1 133 ? 96.12610  -27.95461 -13.00247 1.000 37.13426  ? 133 PRO A C   1 
ATOM   998  O  O   . PRO A 1 133 ? 95.47391  -28.15098 -14.03531 1.000 37.86283  ? 133 PRO A O   1 
ATOM   999  C  CB  . PRO A 1 133 ? 98.40158  -29.01977 -12.69085 1.000 41.25319  ? 133 PRO A CB  1 
ATOM   1000 C  CG  . PRO A 1 133 ? 99.67434  -28.50461 -12.09845 1.000 39.10709  ? 133 PRO A CG  1 
ATOM   1001 C  CD  . PRO A 1 133 ? 99.29466  -27.24466 -11.37162 1.000 43.83525  ? 133 PRO A CD  1 
ATOM   1002 N  N   . ALA A 1 134 ? 95.55229  -27.90143 -11.79681 1.000 34.04117  ? 134 ALA A N   1 
ATOM   1003 C  CA  . ALA A 1 134 ? 94.10888  -28.07647 -11.66009 1.000 39.23867  ? 134 ALA A CA  1 
ATOM   1004 C  C   . ALA A 1 134 ? 93.33769  -26.91709 -12.27914 1.000 39.78471  ? 134 ALA A C   1 
ATOM   1005 O  O   . ALA A 1 134 ? 92.21466  -27.10861 -12.75864 1.000 38.20812  ? 134 ALA A O   1 
ATOM   1006 C  CB  . ALA A 1 134 ? 93.73010  -28.23706 -10.18705 1.000 38.78392  ? 134 ALA A CB  1 
ATOM   1007 N  N   . TRP A 1 135 ? 93.90644  -25.70917 -12.25493 1.000 37.92604  ? 135 TRP A N   1 
ATOM   1008 C  CA  . TRP A 1 135 ? 93.27506  -24.58152 -12.93313 1.000 39.11036  ? 135 TRP A CA  1 
ATOM   1009 C  C   . TRP A 1 135 ? 93.27831  -24.78447 -14.44577 1.000 34.02308  ? 135 TRP A C   1 
ATOM   1010 O  O   . TRP A 1 135 ? 92.27569  -24.51591 -15.11728 1.000 36.19173  ? 135 TRP A O   1 
ATOM   1011 C  CB  . TRP A 1 135 ? 93.98951  -23.28055 -12.55476 1.000 33.93643  ? 135 TRP A CB  1 
ATOM   1012 C  CG  . TRP A 1 135 ? 93.33738  -22.03917 -13.09217 1.000 37.73834  ? 135 TRP A CG  1 
ATOM   1013 C  CD1 . TRP A 1 135 ? 92.43460  -21.24420 -12.44724 1.000 41.41511  ? 135 TRP A CD1 1 
ATOM   1014 C  CD2 . TRP A 1 135 ? 93.53906  -21.44910 -14.38560 1.000 37.30486  ? 135 TRP A CD2 1 
ATOM   1015 N  NE1 . TRP A 1 135 ? 92.06026  -20.19871 -13.25683 1.000 37.58175  ? 135 TRP A NE1 1 
ATOM   1016 C  CE2 . TRP A 1 135 ? 92.72518  -20.30015 -14.45095 1.000 38.80051  ? 135 TRP A CE2 1 
ATOM   1017 C  CE3 . TRP A 1 135 ? 94.32839  -21.78098 -15.49252 1.000 34.50270  ? 135 TRP A CE3 1 
ATOM   1018 C  CZ2 . TRP A 1 135 ? 92.67612  -19.48040 -15.58065 1.000 36.74513  ? 135 TRP A CZ2 1 
ATOM   1019 C  CZ3 . TRP A 1 135 ? 94.27922  -20.96533 -16.61486 1.000 39.02706  ? 135 TRP A CZ3 1 
ATOM   1020 C  CH2 . TRP A 1 135 ? 93.45642  -19.82925 -16.64947 1.000 38.65811  ? 135 TRP A CH2 1 
ATOM   1021 N  N   . CYS A 1 136 ? 94.39274  -25.27233 -14.99451 1.000 32.36744  ? 136 CYS A N   1 
ATOM   1022 C  CA  . CYS A 1 136 ? 94.47373  -25.52221 -16.43055 1.000 40.03388  ? 136 CYS A CA  1 
ATOM   1023 C  C   . CYS A 1 136 ? 93.45325  -26.56427 -16.86103 1.000 41.04143  ? 136 CYS A C   1 
ATOM   1024 O  O   . CYS A 1 136 ? 92.76879  -26.39673 -17.87664 1.000 42.34413  ? 136 CYS A O   1 
ATOM   1025 C  CB  . CYS A 1 136 ? 95.88502  -25.97438 -16.80506 1.000 41.84478  ? 136 CYS A CB  1 
ATOM   1026 S  SG  . CYS A 1 136 ? 97.19288  -24.82634 -16.32330 1.000 56.82399  ? 136 CYS A SG  1 
ATOM   1027 N  N   . ALA A 1 137 ? 93.33992  -27.65340 -16.09512 1.000 39.76578  ? 137 ALA A N   1 
ATOM   1028 C  CA  . ALA A 1 137 ? 92.39691  -28.70909 -16.44631 1.000 39.82902  ? 137 ALA A CA  1 
ATOM   1029 C  C   . ALA A 1 137 ? 90.96621  -28.19037 -16.44534 1.000 39.01663  ? 137 ALA A C   1 
ATOM   1030 O  O   . ALA A 1 137 ? 90.18245  -28.50181 -17.35097 1.000 39.87538  ? 137 ALA A O   1 
ATOM   1031 C  CB  . ALA A 1 137 ? 92.54461  -29.88643 -15.48242 1.000 40.38283  ? 137 ALA A CB  1 
ATOM   1032 N  N   . ARG A 1 138 ? 90.61021  -27.38911 -15.44003 1.000 36.64104  ? 138 ARG A N   1 
ATOM   1033 C  CA  . ARG A 1 138 ? 89.26112  -26.83943 -15.37762 1.000 36.59794  ? 138 ARG A CA  1 
ATOM   1034 C  C   . ARG A 1 138 ? 89.01291  -25.85519 -16.51392 1.000 38.73430  ? 138 ARG A C   1 
ATOM   1035 O  O   . ARG A 1 138 ? 87.93788  -25.86308 -17.12471 1.000 37.30320  ? 138 ARG A O   1 
ATOM   1036 C  CB  . ARG A 1 138 ? 89.03678  -26.16334 -14.02725 1.000 40.00519  ? 138 ARG A CB  1 
ATOM   1037 C  CG  . ARG A 1 138 ? 87.60313  -25.73817 -13.76606 1.000 38.95728  ? 138 ARG A CG  1 
ATOM   1038 C  CD  . ARG A 1 138 ? 87.51872  -24.92504 -12.47546 1.000 45.66053  ? 138 ARG A CD  1 
ATOM   1039 N  NE  . ARG A 1 138 ? 88.13678  -23.61251 -12.62857 1.000 43.91546  ? 138 ARG A NE  1 
ATOM   1040 C  CZ  . ARG A 1 138 ? 88.64432  -22.89341 -11.63581 1.000 45.71591  ? 138 ARG A CZ  1 
ATOM   1041 N  NH1 . ARG A 1 138 ? 88.66777  -23.34613 -10.39242 1.000 43.70986  ? 138 ARG A NH1 1 
ATOM   1042 N  NH2 . ARG A 1 138 ? 89.14987  -21.69176 -11.89877 1.000 45.87234  ? 138 ARG A NH2 1 
ATOM   1043 N  N   . SER A 1 139 ? 89.99334  -24.99501 -16.80535 1.000 32.44431  ? 139 SER A N   1 
ATOM   1044 C  CA  . SER A 1 139 ? 89.83988  -24.03583 -17.89411 1.000 40.22204  ? 139 SER A CA  1 
ATOM   1045 C  C   . SER A 1 139 ? 89.78063  -24.73191 -19.24651 1.000 35.80372  ? 139 SER A C   1 
ATOM   1046 O  O   . SER A 1 139 ? 89.08002  -24.26454 -20.15110 1.000 37.69238  ? 139 SER A O   1 
ATOM   1047 C  CB  . SER A 1 139 ? 90.98169  -23.01861 -17.86596 1.000 34.54970  ? 139 SER A CB  1 
ATOM   1048 O  OG  . SER A 1 139 ? 90.89695  -22.19444 -16.71607 1.000 39.41725  ? 139 SER A OG  1 
ATOM   1049 N  N   . ALA A 1 140 ? 90.50380  -25.84415 -19.40148 1.000 37.61469  ? 140 ALA A N   1 
ATOM   1050 C  CA  . ALA A 1 140 ? 90.41548  -26.61771 -20.63558 1.000 39.87702  ? 140 ALA A CA  1 
ATOM   1051 C  C   . ALA A 1 140 ? 89.02405  -27.20741 -20.81329 1.000 41.24546  ? 140 ALA A C   1 
ATOM   1052 O  O   . ALA A 1 140 ? 88.50031  -27.24997 -21.93251 1.000 42.25365  ? 140 ALA A O   1 
ATOM   1053 C  CB  . ALA A 1 140 ? 91.47313  -27.72073 -20.64410 1.000 39.47934  ? 140 ALA A CB  1 
ATOM   1054 N  N   . ARG A 1 141 ? 88.40638  -27.66362 -19.71792 1.000 39.32994  ? 141 ARG A N   1 
ATOM   1055 C  CA  . ARG A 1 141 ? 87.04045  -28.17060 -19.79837 1.000 39.59540  ? 141 ARG A CA  1 
ATOM   1056 C  C   . ARG A 1 141 ? 86.07595  -27.07936 -20.23807 1.000 41.79367  ? 141 ARG A C   1 
ATOM   1057 O  O   . ARG A 1 141 ? 85.14194  -27.33983 -21.00740 1.000 38.12828  ? 141 ARG A O   1 
ATOM   1058 C  CB  . ARG A 1 141 ? 86.60676  -28.75633 -18.45280 1.000 38.84123  ? 141 ARG A CB  1 
ATOM   1059 C  CG  . ARG A 1 141 ? 87.41161  -29.97411 -18.03002 1.000 52.64743  ? 141 ARG A CG  1 
ATOM   1060 C  CD  . ARG A 1 141 ? 86.73062  -30.74868 -16.90196 1.000 57.67389  ? 141 ARG A CD  1 
ATOM   1061 N  NE  . ARG A 1 141 ? 86.70906  -30.02092 -15.63750 1.000 47.70305  ? 141 ARG A NE  1 
ATOM   1062 C  CZ  . ARG A 1 141 ? 87.69610  -30.03339 -14.75122 1.000 56.02923  ? 141 ARG A CZ  1 
ATOM   1063 N  NH1 . ARG A 1 141 ? 88.81555  -30.70352 -14.97194 1.000 48.89813  ? 141 ARG A NH1 1 
ATOM   1064 N  NH2 . ARG A 1 141 ? 87.55701  -29.35731 -13.61421 1.000 54.88104  ? 141 ARG A NH2 1 
ATOM   1065 N  N   . HIS A 1 142 ? 86.28464  -25.85026 -19.75616 1.000 38.79918  ? 142 HIS A N   1 
ATOM   1066 C  CA  . HIS A 1 142 ? 85.45087  -24.73311 -20.18931 1.000 38.90402  ? 142 HIS A CA  1 
ATOM   1067 C  C   . HIS A 1 142 ? 85.57952  -24.49371 -21.68979 1.000 36.04325  ? 142 HIS A C   1 
ATOM   1068 O  O   . HIS A 1 142 ? 84.58326  -24.22033 -22.36885 1.000 35.15977  ? 142 HIS A O   1 
ATOM   1069 C  CB  . HIS A 1 142 ? 85.82327  -23.47058 -19.41628 1.000 38.00215  ? 142 HIS A CB  1 
ATOM   1070 C  CG  . HIS A 1 142 ? 85.52929  -23.54748 -17.95079 1.000 41.40252  ? 142 HIS A CG  1 
ATOM   1071 N  ND1 . HIS A 1 142 ? 86.26717  -22.86530 -17.00760 1.000 38.51807  ? 142 HIS A ND1 1 
ATOM   1072 C  CD2 . HIS A 1 142 ? 84.57271  -24.21894 -17.26657 1.000 42.07093  ? 142 HIS A CD2 1 
ATOM   1073 C  CE1 . HIS A 1 142 ? 85.78041  -23.11599 -15.80488 1.000 40.15582  ? 142 HIS A CE1 1 
ATOM   1074 N  NE2 . HIS A 1 142 ? 84.75195  -23.93455 -15.93404 1.000 42.06023  ? 142 HIS A NE2 1 
ATOM   1075 N  N   . TRP A 1 143 ? 86.79891  -24.58570 -22.22509 1.000 33.86764  ? 143 TRP A N   1 
ATOM   1076 C  CA  . TRP A 1 143 ? 86.97778  -24.44263 -23.66681 1.000 39.69724  ? 143 TRP A CA  1 
ATOM   1077 C  C   . TRP A 1 143 ? 86.24272  -25.54035 -24.42937 1.000 37.68189  ? 143 TRP A C   1 
ATOM   1078 O  O   . TRP A 1 143 ? 85.61925  -25.27416 -25.46281 1.000 40.22292  ? 143 TRP A O   1 
ATOM   1079 C  CB  . TRP A 1 143 ? 88.46501  -24.45178 -24.02081 1.000 34.25283  ? 143 TRP A CB  1 
ATOM   1080 C  CG  . TRP A 1 143 ? 89.14398  -23.11504 -23.90634 1.000 37.32610  ? 143 TRP A CG  1 
ATOM   1081 C  CD1 . TRP A 1 143 ? 90.24866  -22.81924 -23.16417 1.000 37.40451  ? 143 TRP A CD1 1 
ATOM   1082 C  CD2 . TRP A 1 143 ? 88.76852  -21.89894 -24.56667 1.000 34.15211  ? 143 TRP A CD2 1 
ATOM   1083 N  NE1 . TRP A 1 143 ? 90.58598  -21.49684 -23.31930 1.000 35.31429  ? 143 TRP A NE1 1 
ATOM   1084 C  CE2 . TRP A 1 143 ? 89.69272  -20.90913 -24.17542 1.000 35.63559  ? 143 TRP A CE2 1 
ATOM   1085 C  CE3 . TRP A 1 143 ? 87.74298  -21.55199 -25.45290 1.000 34.14686  ? 143 TRP A CE3 1 
ATOM   1086 C  CZ2 . TRP A 1 143 ? 89.62112  -19.59601 -24.63665 1.000 33.72396  ? 143 TRP A CZ2 1 
ATOM   1087 C  CZ3 . TRP A 1 143 ? 87.67125  -20.24424 -25.90716 1.000 34.42878  ? 143 TRP A CZ3 1 
ATOM   1088 C  CH2 . TRP A 1 143 ? 88.60607  -19.28511 -25.50076 1.000 33.43187  ? 143 TRP A CH2 1 
ATOM   1089 N  N   . ARG A 1 144 ? 86.29689  -26.78047 -23.93292 1.000 39.25868  ? 144 ARG A N   1 
ATOM   1090 C  CA  . ARG A 1 144 ? 85.62935  -27.88004 -24.62540 1.000 40.90423  ? 144 ARG A CA  1 
ATOM   1091 C  C   . ARG A 1 144 ? 84.11847  -27.69232 -24.63944 1.000 41.65519  ? 144 ARG A C   1 
ATOM   1092 O  O   . ARG A 1 144 ? 83.45911  -28.01150 -25.63630 1.000 38.54214  ? 144 ARG A O   1 
ATOM   1093 C  CB  . ARG A 1 144 ? 86.00446  -29.21823 -23.98690 1.000 38.98097  ? 144 ARG A CB  1 
ATOM   1094 C  CG  . ARG A 1 144 ? 87.46368  -29.58944 -24.19965 1.000 44.73269  ? 144 ARG A CG  1 
ATOM   1095 C  CD  . ARG A 1 144 ? 87.73982  -31.05876 -23.91622 1.000 47.07626  ? 144 ARG A CD  1 
ATOM   1096 N  NE  . ARG A 1 144 ? 89.17014  -31.34275 -23.93791 1.000 41.44313  ? 144 ARG A NE  1 
ATOM   1097 C  CZ  . ARG A 1 144 ? 89.96370  -31.25304 -22.87795 1.000 53.61563  ? 144 ARG A CZ  1 
ATOM   1098 N  NH1 . ARG A 1 144 ? 89.49289  -30.91894 -21.68585 1.000 45.72765  ? 144 ARG A NH1 1 
ATOM   1099 N  NH2 . ARG A 1 144 ? 91.26273  -31.50094 -23.01647 1.000 54.31580  ? 144 ARG A NH2 1 
ATOM   1100 N  N   . ASN A 1 145 ? 83.54932  -27.17710 -23.54474 1.000 36.99937  ? 145 ASN A N   1 
ATOM   1101 C  CA  . ASN A 1 145 ? 82.12754  -26.84465 -23.55026 1.000 40.32392  ? 145 ASN A CA  1 
ATOM   1102 C  C   . ASN A 1 145 ? 81.81732  -25.79367 -24.60930 1.000 42.46194  ? 145 ASN A C   1 
ATOM   1103 O  O   . ASN A 1 145 ? 80.76825  -25.84461 -25.26015 1.000 39.31394  ? 145 ASN A O   1 
ATOM   1104 C  CB  . ASN A 1 145 ? 81.68781  -26.34541 -22.17425 1.000 36.07234  ? 145 ASN A CB  1 
ATOM   1105 C  CG  . ASN A 1 145 ? 81.82778  -27.39998 -21.08720 1.000 51.76773  ? 145 ASN A CG  1 
ATOM   1106 O  OD1 . ASN A 1 145 ? 82.07381  -28.57335 -21.36404 1.000 46.74278  ? 145 ASN A OD1 1 
ATOM   1107 N  ND2 . ASN A 1 145 ? 81.65833  -26.98092 -19.83850 1.000 43.38524  ? 145 ASN A ND2 1 
ATOM   1108 N  N   . TYR A 1 146 ? 82.72163  -24.83046 -24.78949 1.000 38.61102  ? 146 TYR A N   1 
ATOM   1109 C  CA  . TYR A 1 146 ? 82.51289  -23.76725 -25.76623 1.000 38.35793  ? 146 TYR A CA  1 
ATOM   1110 C  C   . TYR A 1 146 ? 82.54390  -24.31487 -27.18960 1.000 42.46297  ? 146 TYR A C   1 
ATOM   1111 O  O   . TYR A 1 146 ? 81.67569  -23.99512 -28.00945 1.000 43.25143  ? 146 TYR A O   1 
ATOM   1112 C  CB  . TYR A 1 146 ? 83.57620  -22.68639 -25.56139 1.000 37.91997  ? 146 TYR A CB  1 
ATOM   1113 C  CG  . TYR A 1 146 ? 83.63671  -21.61237 -26.62095 1.000 38.22128  ? 146 TYR A CG  1 
ATOM   1114 C  CD1 . TYR A 1 146 ? 82.78938  -20.51201 -26.57549 1.000 42.09166  ? 146 TYR A CD1 1 
ATOM   1115 C  CD2 . TYR A 1 146 ? 84.56772  -21.67950 -27.64861 1.000 38.33369  ? 146 TYR A CD2 1 
ATOM   1116 C  CE1 . TYR A 1 146 ? 82.85295  -19.51544 -27.54302 1.000 48.46413  ? 146 TYR A CE1 1 
ATOM   1117 C  CE2 . TYR A 1 146 ? 84.64115  -20.68852 -28.61913 1.000 42.53602  ? 146 TYR A CE2 1 
ATOM   1118 C  CZ  . TYR A 1 146 ? 83.78140  -19.61017 -28.56165 1.000 45.79529  ? 146 TYR A CZ  1 
ATOM   1119 O  OH  . TYR A 1 146 ? 83.85315  -18.62454 -29.52438 1.000 57.55037  ? 146 TYR A OH  1 
ATOM   1120 N  N   . PHE A 1 147 ? 83.53399  -25.15428 -27.49599 1.000 37.58558  ? 147 PHE A N   1 
ATOM   1121 C  CA  . PHE A 1 147 ? 83.63878  -25.72576 -28.83377 1.000 44.46221  ? 147 PHE A CA  1 
ATOM   1122 C  C   . PHE A 1 147 ? 82.46956  -26.65736 -29.12719 1.000 45.58404  ? 147 PHE A C   1 
ATOM   1123 O  O   . PHE A 1 147 ? 81.88110  -26.60800 -30.21410 1.000 42.37988  ? 147 PHE A O   1 
ATOM   1124 C  CB  . PHE A 1 147 ? 84.97129  -26.45801 -28.97985 1.000 38.30747  ? 147 PHE A CB  1 
ATOM   1125 C  CG  . PHE A 1 147 ? 86.16330  -25.54932 -28.94888 1.000 37.45318  ? 147 PHE A CG  1 
ATOM   1126 C  CD1 . PHE A 1 147 ? 86.23948  -24.45615 -29.79766 1.000 44.10846  ? 147 PHE A CD1 1 
ATOM   1127 C  CD2 . PHE A 1 147 ? 87.20354  -25.78099 -28.06635 1.000 39.95649  ? 147 PHE A CD2 1 
ATOM   1128 C  CE1 . PHE A 1 147 ? 87.33712  -23.61613 -29.77209 1.000 42.24179  ? 147 PHE A CE1 1 
ATOM   1129 C  CE2 . PHE A 1 147 ? 88.30191  -24.94469 -28.03296 1.000 39.79773  ? 147 PHE A CE2 1 
ATOM   1130 C  CZ  . PHE A 1 147 ? 88.36939  -23.85984 -28.88592 1.000 41.22754  ? 147 PHE A CZ  1 
ATOM   1131 N  N   . ASP A 1 148 ? 82.11885  -27.51728 -28.16486 1.000 38.44027  ? 148 ASP A N   1 
ATOM   1132 C  CA  . ASP A 1 148 ? 80.94710  -28.37391 -28.32445 1.000 41.77219  ? 148 ASP A CA  1 
ATOM   1133 C  C   . ASP A 1 148 ? 79.68506  -27.56055 -28.57115 1.000 47.67739  ? 148 ASP A C   1 
ATOM   1134 O  O   . ASP A 1 148 ? 78.79991  -28.00260 -29.31211 1.000 44.39755  ? 148 ASP A O   1 
ATOM   1135 C  CB  . ASP A 1 148 ? 80.75941  -29.25523 -27.08989 1.000 43.96085  ? 148 ASP A CB  1 
ATOM   1136 C  CG  . ASP A 1 148 ? 81.82980  -30.31724 -26.95976 1.000 47.22087  ? 148 ASP A CG  1 
ATOM   1137 O  OD1 . ASP A 1 148 ? 82.59225  -30.51964 -27.92772 1.000 54.82229  ? 148 ASP A OD1 1 
ATOM   1138 O  OD2 . ASP A 1 148 ? 81.91101  -30.94586 -25.88157 1.000 57.20523  ? 148 ASP A OD2 1 
ATOM   1139 N  N   . GLY A 1 149 ? 79.58083  -26.37702 -27.95939 1.000 42.39285  ? 149 GLY A N   1 
ATOM   1140 C  CA  . GLY A 1 149 ? 78.41018  -25.54339 -28.17180 1.000 41.11886  ? 149 GLY A CA  1 
ATOM   1141 C  C   . GLY A 1 149 ? 78.23688  -25.10718 -29.61399 1.000 46.90351  ? 149 GLY A C   1 
ATOM   1142 O  O   . GLY A 1 149 ? 77.10801  -24.94598 -30.08515 1.000 46.13285  ? 149 GLY A O   1 
ATOM   1143 N  N   . TYR A 1 150 ? 79.34373  -24.89801 -30.33127 1.000 39.73091  ? 150 TYR A N   1 
ATOM   1144 C  CA  . TYR A 1 150 ? 79.24525  -24.54720 -31.74506 1.000 48.39476  ? 150 TYR A CA  1 
ATOM   1145 C  C   . TYR A 1 150 ? 78.67949  -25.70092 -32.56212 1.000 47.76765  ? 150 TYR A C   1 
ATOM   1146 O  O   . TYR A 1 150 ? 77.90371  -25.48189 -33.49912 1.000 49.09929  ? 150 TYR A O   1 
ATOM   1147 C  CB  . TYR A 1 150 ? 80.61269  -24.12430 -32.27962 1.000 43.38577  ? 150 TYR A CB  1 
ATOM   1148 C  CG  . TYR A 1 150 ? 80.89559  -22.65763 -32.07613 1.000 50.42730  ? 150 TYR A CG  1 
ATOM   1149 C  CD1 . TYR A 1 150 ? 81.13481  -22.14781 -30.80694 1.000 47.74632  ? 150 TYR A CD1 1 
ATOM   1150 C  CD2 . TYR A 1 150 ? 80.90957  -21.77745 -33.15098 1.000 43.92699  ? 150 TYR A CD2 1 
ATOM   1151 C  CE1 . TYR A 1 150 ? 81.38623  -20.79946 -30.61288 1.000 52.28812  ? 150 TYR A CE1 1 
ATOM   1152 C  CE2 . TYR A 1 150 ? 81.16025  -20.42927 -32.96758 1.000 45.76683  ? 150 TYR A CE2 1 
ATOM   1153 C  CZ  . TYR A 1 150 ? 81.39888  -19.94469 -31.69660 1.000 53.45425  ? 150 TYR A CZ  1 
ATOM   1154 O  OH  . TYR A 1 150 ? 81.65031  -18.60451 -31.51057 1.000 46.95886  ? 150 TYR A OH  1 
ATOM   1155 N  N   . VAL A 1 151 ? 79.05415  -26.93575 -32.22131 1.000 48.67596  ? 151 VAL A N   1 
ATOM   1156 C  CA  . VAL A 1 151 ? 78.49696  -28.09618 -32.90994 1.000 50.71693  ? 151 VAL A CA  1 
ATOM   1157 C  C   . VAL A 1 151 ? 76.99460  -28.18383 -32.67398 1.000 52.95121  ? 151 VAL A C   1 
ATOM   1158 O  O   . VAL A 1 151 ? 76.22008  -28.44439 -33.60262 1.000 47.67628  ? 151 VAL A O   1 
ATOM   1159 C  CB  . VAL A 1 151 ? 79.21822  -29.38001 -32.46128 1.000 48.34908  ? 151 VAL A CB  1 
ATOM   1160 C  CG1 . VAL A 1 151 ? 78.61292  -30.59330 -33.15039 1.000 50.94423  ? 151 VAL A CG1 1 
ATOM   1161 C  CG2 . VAL A 1 151 ? 80.70982  -29.27818 -32.74942 1.000 41.33192  ? 151 VAL A CG2 1 
ATOM   1162 N  N   . ASP A 1 152 ? 76.55945  -27.96193 -31.43011 1.000 44.52070  ? 152 ASP A N   1 
ATOM   1163 C  CA  . ASP A 1 152 ? 75.13321  -27.99761 -31.12135 1.000 46.36150  ? 152 ASP A CA  1 
ATOM   1164 C  C   . ASP A 1 152 ? 74.36508  -26.94458 -31.90958 1.000 53.88548  ? 152 ASP A C   1 
ATOM   1165 O  O   . ASP A 1 152 ? 73.28299  -27.22423 -32.43891 1.000 50.11990  ? 152 ASP A O   1 
ATOM   1166 C  CB  . ASP A 1 152 ? 74.91647  -27.79978 -29.62120 1.000 50.02246  ? 152 ASP A CB  1 
ATOM   1167 C  CG  . ASP A 1 152 ? 75.44877  -28.95674 -28.79684 1.000 59.85726  ? 152 ASP A CG  1 
ATOM   1168 O  OD1 . ASP A 1 152 ? 75.77751  -30.01197 -29.38373 1.000 61.68766  ? 152 ASP A OD1 1 
ATOM   1169 O  OD2 . ASP A 1 152 ? 75.54057  -28.80878 -27.56091 1.000 58.74585  ? 152 ASP A OD2 1 
ATOM   1170 N  N   . GLU A 1 153 ? 74.90428  -25.72460 -31.99446 1.000 51.24490  ? 153 GLU A N   1 
ATOM   1171 C  CA  . GLU A 1 153 ? 74.22269  -24.66930 -32.73804 1.000 53.34179  ? 153 GLU A CA  1 
ATOM   1172 C  C   . GLU A 1 153 ? 74.10796  -25.01875 -34.21626 1.000 48.38710  ? 153 GLU A C   1 
ATOM   1173 O  O   . GLU A 1 153 ? 73.08703  -24.73119 -34.85054 1.000 52.92893  ? 153 GLU A O   1 
ATOM   1174 C  CB  . GLU A 1 153 ? 74.95073  -23.33776 -32.55595 1.000 51.47682  ? 153 GLU A CB  1 
ATOM   1175 C  CG  . GLU A 1 153 ? 74.74721  -22.70517 -31.19026 1.000 60.21442  ? 153 GLU A CG  1 
ATOM   1176 C  CD  . GLU A 1 153 ? 75.23045  -21.26771 -31.13311 1.000 73.33346  ? 153 GLU A CD  1 
ATOM   1177 O  OE1 . GLU A 1 153 ? 76.11412  -20.89960 -31.93874 1.000 69.71762  ? 153 GLU A OE1 1 
ATOM   1178 O  OE2 . GLU A 1 153 ? 74.72408  -20.50429 -30.28138 1.000 62.29229  ? 153 GLU A OE2 1 
ATOM   1179 N  N   . ALA A 1 154 ? 75.14714  -25.63639 -34.78397 1.000 46.46325  ? 154 ALA A N   1 
ATOM   1180 C  CA  . ALA A 1 154 ? 75.07761  -26.06742 -36.17602 1.000 55.28881  ? 154 ALA A CA  1 
ATOM   1181 C  C   . ALA A 1 154 ? 74.03108  -27.15665 -36.37159 1.000 60.01006  ? 154 ALA A C   1 
ATOM   1182 O  O   . ALA A 1 154 ? 73.39167  -27.21714 -37.42829 1.000 57.46034  ? 154 ALA A O   1 
ATOM   1183 C  CB  . ALA A 1 154 ? 76.44837  -26.55409 -36.64848 1.000 48.49862  ? 154 ALA A CB  1 
ATOM   1184 N  N   . GLU A 1 155 ? 73.83791  -28.01963 -35.36885 1.000 58.12992  ? 155 GLU A N   1 
ATOM   1185 C  CA  . GLU A 1 155 ? 72.79085  -29.03383 -35.45509 1.000 58.11374  ? 155 GLU A CA  1 
ATOM   1186 C  C   . GLU A 1 155 ? 71.40984  -28.39402 -35.49773 1.000 60.43019  ? 155 GLU A C   1 
ATOM   1187 O  O   . GLU A 1 155 ? 70.54994  -28.79926 -36.28858 1.000 63.64820  ? 155 GLU A O   1 
ATOM   1188 C  CB  . GLU A 1 155 ? 72.88925  -30.00142 -34.27670 1.000 57.18339  ? 155 GLU A CB  1 
ATOM   1189 C  CG  . GLU A 1 155 ? 73.98081  -31.04754 -34.40249 1.000 62.43264  ? 155 GLU A CG  1 
ATOM   1190 C  CD  . GLU A 1 155 ? 74.02456  -31.97877 -33.20378 1.000 77.02512  ? 155 GLU A CD  1 
ATOM   1191 O  OE1 . GLU A 1 155 ? 73.13205  -31.87761 -32.33076 1.000 75.80438  ? 155 GLU A OE1 1 
ATOM   1192 O  OE2 . GLU A 1 155 ? 74.95396  -32.81078 -33.13305 1.000 80.50852  ? 155 GLU A OE2 1 
ATOM   1193 N  N   . SER A 1 156 ? 71.17691  -27.39475 -34.64142 1.000 56.12378  ? 156 SER A N   1 
ATOM   1194 C  CA  . SER A 1 156 ? 69.87349  -26.73708 -34.60053 1.000 61.59525  ? 156 SER A CA  1 
ATOM   1195 C  C   . SER A 1 156 ? 69.52181  -26.11200 -35.94573 1.000 64.98111  ? 156 SER A C   1 
ATOM   1196 O  O   . SER A 1 156 ? 68.36351  -26.15810 -36.37690 1.000 65.22456  ? 156 SER A O   1 
ATOM   1197 C  CB  . SER A 1 156 ? 69.85761  -25.67758 -33.49857 1.000 57.77190  ? 156 SER A CB  1 
ATOM   1198 O  OG  . SER A 1 156 ? 68.68441  -24.88433 -33.56127 1.000 62.36493  ? 156 SER A OG  1 
ATOM   1199 N  N   . ARG A 1 157 ? 70.50737  -25.51960 -36.62305 1.000 57.99120  ? 157 ARG A N   1 
ATOM   1200 C  CA  . ARG A 1 157 ? 70.23891  -24.90475 -37.91812 1.000 65.88366  ? 157 ARG A CA  1 
ATOM   1201 C  C   . ARG A 1 157 ? 70.02366  -25.95983 -38.99382 1.000 67.56779  ? 157 ARG A C   1 
ATOM   1202 O  O   . ARG A 1 157 ? 69.10861  -25.83770 -39.81683 1.000 74.15789  ? 157 ARG A O   1 
ATOM   1203 C  CB  . ARG A 1 157 ? 71.38616  -23.97358 -38.30897 1.000 62.97857  ? 157 ARG A CB  1 
ATOM   1204 C  CG  . ARG A 1 157 ? 71.67360  -22.88154 -37.29674 1.000 62.44246  ? 157 ARG A CG  1 
ATOM   1205 C  CD  . ARG A 1 157 ? 72.69458  -21.89563 -37.83397 1.000 65.94464  ? 157 ARG A CD  1 
ATOM   1206 N  NE  . ARG A 1 157 ? 73.08637  -20.91550 -36.82813 1.000 65.03443  ? 157 ARG A NE  1 
ATOM   1207 N  N   . PHE A 1 158 ? 70.85236  -27.00614 -38.99653 1.000 64.52404  ? 158 PHE A N   1 
ATOM   1208 C  CA  . PHE A 1 158 ? 70.77919  -28.01117 -40.05166 1.000 69.43865  ? 158 PHE A CA  1 
ATOM   1209 C  C   . PHE A 1 158 ? 69.43819  -28.73155 -40.03624 1.000 71.56402  ? 158 PHE A C   1 
ATOM   1210 O  O   . PHE A 1 158 ? 68.76425  -28.83514 -41.06729 1.000 78.75698  ? 158 PHE A O   1 
ATOM   1211 C  CB  . PHE A 1 158 ? 71.92744  -29.00946 -39.90832 1.000 69.23182  ? 158 PHE A CB  1 
ATOM   1212 C  CG  . PHE A 1 158 ? 71.83482  -30.17661 -40.85065 1.000 74.57893  ? 158 PHE A CG  1 
ATOM   1213 C  CD1 . PHE A 1 158 ? 71.85775  -29.98059 -42.22255 1.000 75.34359  ? 158 PHE A CD1 1 
ATOM   1214 C  CD2 . PHE A 1 158 ? 71.73403  -31.47038 -40.36569 1.000 80.09716  ? 158 PHE A CD2 1 
ATOM   1215 C  CE1 . PHE A 1 158 ? 71.77348  -31.05449 -43.09334 1.000 79.61943  ? 158 PHE A CE1 1 
ATOM   1216 C  CE2 . PHE A 1 158 ? 71.65229  -32.54715 -41.23005 1.000 82.57901  ? 158 PHE A CE2 1 
ATOM   1217 C  CZ  . PHE A 1 158 ? 71.67159  -32.33903 -42.59522 1.000 76.64045  ? 158 PHE A CZ  1 
ATOM   1218 N  N   . TRP A 1 159 ? 69.02952  -29.22907 -38.87284 1.000 73.78876  ? 159 TRP A N   1 
ATOM   1219 C  CA  . TRP A 1 159 ? 67.78724  -29.98017 -38.75483 1.000 71.95386  ? 159 TRP A CA  1 
ATOM   1220 C  C   . TRP A 1 159 ? 66.55759  -29.08858 -38.66250 1.000 71.79819  ? 159 TRP A C   1 
ATOM   1221 O  O   . TRP A 1 159 ? 65.46992  -29.60087 -38.37770 1.000 74.29017  ? 159 TRP A O   1 
ATOM   1222 C  CB  . TRP A 1 159 ? 67.85135  -30.91157 -37.54107 1.000 67.61517  ? 159 TRP A CB  1 
ATOM   1223 C  CG  . TRP A 1 159 ? 68.93212  -31.93745 -37.65902 1.000 74.67608  ? 159 TRP A CG  1 
ATOM   1224 C  CD1 . TRP A 1 159 ? 70.13763  -31.93623 -37.02085 1.000 77.93122  ? 159 TRP A CD1 1 
ATOM   1225 C  CD2 . TRP A 1 159 ? 68.91689  -33.10752 -38.48650 1.000 87.71296  ? 159 TRP A CD2 1 
ATOM   1226 N  NE1 . TRP A 1 159 ? 70.87016  -33.03796 -37.39100 1.000 84.69758  ? 159 TRP A NE1 1 
ATOM   1227 C  CE2 . TRP A 1 159 ? 70.14354  -33.77309 -38.29049 1.000 87.01921  ? 159 TRP A CE2 1 
ATOM   1228 C  CE3 . TRP A 1 159 ? 67.98308  -33.65936 -39.37015 1.000 85.57265  ? 159 TRP A CE3 1 
ATOM   1229 C  CZ2 . TRP A 1 159 ? 70.46141  -34.96272 -38.94535 1.000 89.40347  ? 159 TRP A CZ2 1 
ATOM   1230 C  CZ3 . TRP A 1 159 ? 68.30037  -34.84071 -40.01949 1.000 85.24804  ? 159 TRP A CZ3 1 
ATOM   1231 C  CH2 . TRP A 1 159 ? 69.52913  -35.47889 -39.80372 1.000 86.68622  ? 159 TRP A CH2 1 
ATOM   1232 N  N   . ASN A 1 160 ? 66.70512  -27.78443 -38.90606 1.000 69.66108  ? 160 ASN A N   1 
ATOM   1233 C  CA  . ASN A 1 160 ? 65.59479  -26.83381 -38.83491 1.000 67.78720  ? 160 ASN A CA  1 
ATOM   1234 C  C   . ASN A 1 160 ? 64.83403  -26.97203 -37.52036 1.000 76.63467  ? 160 ASN A C   1 
ATOM   1235 O  O   . ASN A 1 160 ? 63.60137  -26.98038 -37.48415 1.000 75.66978  ? 160 ASN A O   1 
ATOM   1236 C  CB  . ASN A 1 160 ? 64.65396  -26.99019 -40.02976 1.000 75.33459  ? 160 ASN A CB  1 
ATOM   1237 C  CG  . ASN A 1 160 ? 64.99944  -26.05161 -41.16801 1.000 81.68028  ? 160 ASN A CG  1 
ATOM   1238 O  OD1 . ASN A 1 160 ? 66.13037  -25.57491 -41.27514 1.000 85.35990  ? 160 ASN A OD1 1 
ATOM   1239 N  ND2 . ASN A 1 160 ? 64.02111  -25.77481 -42.02316 1.000 90.99883  ? 160 ASN A ND2 1 
ATOM   1240 N  N   . ALA A 1 161 ? 65.58174  -27.09645 -36.42993 1.000 73.85648  ? 161 ALA A N   1 
ATOM   1241 C  CA  . ALA A 1 161 ? 64.99363  -27.16204 -35.10174 1.000 75.91750  ? 161 ALA A CA  1 
ATOM   1242 C  C   . ALA A 1 161 ? 65.34556  -25.89780 -34.32833 1.000 74.66305  ? 161 ALA A C   1 
ATOM   1243 O  O   . ALA A 1 161 ? 66.29085  -25.90369 -33.52894 1.000 73.14484  ? 161 ALA A O   1 
ATOM   1244 C  CB  . ALA A 1 161 ? 65.47721  -28.40617 -34.35422 1.000 65.41284  ? 161 ALA A CB  1 
ATOM   1245 N  N   . PRO A 1 162 ? 64.62949  -24.79590 -34.54548 1.000 73.94040  ? 162 PRO A N   1 
ATOM   1246 C  CA  . PRO A 1 162 ? 64.87704  -23.59644 -33.74235 1.000 73.59139  ? 162 PRO A CA  1 
ATOM   1247 C  C   . PRO A 1 162 ? 64.41743  -23.80479 -32.30923 1.000 77.16153  ? 162 PRO A C   1 
ATOM   1248 O  O   . PRO A 1 162 ? 63.53509  -24.61981 -32.02539 1.000 72.58277  ? 162 PRO A O   1 
ATOM   1249 C  CB  . PRO A 1 162 ? 64.04507  -22.51930 -34.44647 1.000 74.94476  ? 162 PRO A CB  1 
ATOM   1250 C  CG  . PRO A 1 162 ? 62.93425  -23.28143 -35.09109 1.000 75.98906  ? 162 PRO A CG  1 
ATOM   1251 C  CD  . PRO A 1 162 ? 63.53087  -24.59826 -35.50823 1.000 69.92953  ? 162 PRO A CD  1 
ATOM   1252 N  N   . CYS A 1 163 ? 65.03935  -23.06020 -31.39864 1.000 74.82518  ? 163 CYS A N   1 
ATOM   1253 C  CA  . CYS A 1 163 ? 64.70655  -23.18267 -29.98637 1.000 72.19210  ? 163 CYS A CA  1 
ATOM   1254 C  C   . CYS A 1 163 ? 63.27248  -22.73072 -29.73930 1.000 73.87330  ? 163 CYS A C   1 
ATOM   1255 O  O   . CYS A 1 163 ? 62.87652  -21.62869 -30.13084 1.000 73.02000  ? 163 CYS A O   1 
ATOM   1256 C  CB  . CYS A 1 163 ? 65.68438  -22.36534 -29.14335 1.000 69.14635  ? 163 CYS A CB  1 
ATOM   1257 S  SG  . CYS A 1 163 ? 67.39656  -22.94317 -29.25087 1.000 74.06189  ? 163 CYS A SG  1 
ATOM   1258 N  N   . ASP A 1 164 ? 62.48977  -23.59696 -29.09764 1.000 78.62104  ? 164 ASP A N   1 
ATOM   1259 C  CA  . ASP A 1 164 ? 61.08057  -23.33087 -28.84542 1.000 81.96665  ? 164 ASP A CA  1 
ATOM   1260 C  C   . ASP A 1 164 ? 60.83005  -22.60687 -27.52964 1.000 79.53029  ? 164 ASP A C   1 
ATOM   1261 O  O   . ASP A 1 164 ? 59.68319  -22.23598 -27.25606 1.000 82.06919  ? 164 ASP A O   1 
ATOM   1262 C  CB  . ASP A 1 164 ? 60.28619  -24.64327 -28.86326 1.000 81.86377  ? 164 ASP A CB  1 
ATOM   1263 N  N   . SER A 1 165 ? 61.86040  -22.39258 -26.71572 1.000 75.69412  ? 165 SER A N   1 
ATOM   1264 C  CA  . SER A 1 165 ? 61.66522  -21.75818 -25.42103 1.000 76.99665  ? 165 SER A CA  1 
ATOM   1265 C  C   . SER A 1 165 ? 62.96058  -21.09151 -24.98671 1.000 77.57920  ? 165 SER A C   1 
ATOM   1266 O  O   . SER A 1 165 ? 64.05127  -21.44958 -25.44181 1.000 71.54722  ? 165 SER A O   1 
ATOM   1267 C  CB  . SER A 1 165 ? 61.20441  -22.76751 -24.36431 1.000 72.64748  ? 165 SER A CB  1 
ATOM   1268 O  OG  . SER A 1 165 ? 62.24449  -23.67087 -24.03845 1.000 76.64612  ? 165 SER A OG  1 
ATOM   1269 N  N   . ALA A 1 166 ? 62.81909  -20.11205 -24.08982 1.000 72.23419  ? 166 ALA A N   1 
ATOM   1270 C  CA  . ALA A 1 166 ? 63.99013  -19.45063 -23.52815 1.000 67.49369  ? 166 ALA A CA  1 
ATOM   1271 C  C   . ALA A 1 166 ? 64.89989  -20.45067 -22.82733 1.000 73.16400  ? 166 ALA A C   1 
ATOM   1272 O  O   . ALA A 1 166 ? 66.12842  -20.36780 -22.94012 1.000 71.17036  ? 166 ALA A O   1 
ATOM   1273 C  CB  . ALA A 1 166 ? 63.55493  -18.34769 -22.56409 1.000 65.82797  ? 166 ALA A CB  1 
ATOM   1274 N  N   . ALA A 1 167 ? 64.31189  -21.41997 -22.12022 1.000 62.91704  ? 167 ALA A N   1 
ATOM   1275 C  CA  . ALA A 1 167 ? 65.11042  -22.37575 -21.35952 1.000 64.84294  ? 167 ALA A CA  1 
ATOM   1276 C  C   . ALA A 1 167 ? 65.98654  -23.22440 -22.27246 1.000 72.58108  ? 167 ALA A C   1 
ATOM   1277 O  O   . ALA A 1 167 ? 67.13691  -23.52852 -21.93342 1.000 71.65690  ? 167 ALA A O   1 
ATOM   1278 C  CB  . ALA A 1 167 ? 64.19802  -23.26350 -20.51337 1.000 67.89638  ? 167 ALA A CB  1 
ATOM   1279 N  N   . GLN A 1 168 ? 65.46132  -23.61960 -23.43463 1.000 74.08502  ? 168 GLN A N   1 
ATOM   1280 C  CA  . GLN A 1 168 ? 66.25165  -24.42699 -24.35825 1.000 71.99839  ? 168 GLN A CA  1 
ATOM   1281 C  C   . GLN A 1 168 ? 67.36370  -23.60401 -24.99569 1.000 67.42673  ? 168 GLN A C   1 
ATOM   1282 O  O   . GLN A 1 168 ? 68.47069  -24.11026 -25.21745 1.000 63.88053  ? 168 GLN A O   1 
ATOM   1283 C  CB  . GLN A 1 168 ? 65.34757  -25.03291 -25.43070 1.000 75.62952  ? 168 GLN A CB  1 
ATOM   1284 C  CG  . GLN A 1 168 ? 64.27215  -25.95662 -24.88617 1.000 76.55342  ? 168 GLN A CG  1 
ATOM   1285 C  CD  . GLN A 1 168 ? 63.30996  -26.42826 -25.95936 1.000 81.10861  ? 168 GLN A CD  1 
ATOM   1286 O  OE1 . GLN A 1 168 ? 63.71162  -27.06256 -26.93488 1.000 83.58696  ? 168 GLN A OE1 1 
ATOM   1287 N  NE2 . GLN A 1 168 ? 62.03109  -26.11300 -25.78715 1.000 78.87028  ? 168 GLN A NE2 1 
ATOM   1288 N  N   . TYR A 1 169 ? 67.08532  -22.33421 -25.29850 1.000 70.25507  ? 169 TYR A N   1 
ATOM   1289 C  CA  . TYR A 1 169 ? 68.10130  -21.46235 -25.87974 1.000 66.70055  ? 169 TYR A CA  1 
ATOM   1290 C  C   . TYR A 1 169 ? 69.24667  -21.23200 -24.90243 1.000 60.48975  ? 169 TYR A C   1 
ATOM   1291 O  O   . TYR A 1 169 ? 70.42081  -21.41314 -25.24920 1.000 50.78848  ? 169 TYR A O   1 
ATOM   1292 C  CB  . TYR A 1 169 ? 67.46187  -20.13717 -26.29599 1.000 58.52653  ? 169 TYR A CB  1 
ATOM   1293 C  CG  . TYR A 1 169 ? 68.41909  -19.11471 -26.87314 1.000 62.10616  ? 169 TYR A CG  1 
ATOM   1294 C  CD1 . TYR A 1 169 ? 69.19687  -19.40850 -27.98526 1.000 61.97826  ? 169 TYR A CD1 1 
ATOM   1295 C  CD2 . TYR A 1 169 ? 68.51948  -17.84277 -26.32312 1.000 61.66048  ? 169 TYR A CD2 1 
ATOM   1296 C  CE1 . TYR A 1 169 ? 70.06299  -18.47069 -28.52021 1.000 57.56713  ? 169 TYR A CE1 1 
ATOM   1297 C  CE2 . TYR A 1 169 ? 69.38175  -16.89894 -26.85060 1.000 59.94727  ? 169 TYR A CE2 1 
ATOM   1298 C  CZ  . TYR A 1 169 ? 70.15040  -17.21745 -27.94926 1.000 58.55414  ? 169 TYR A CZ  1 
ATOM   1299 O  OH  . TYR A 1 169 ? 71.00977  -16.28079 -28.47615 1.000 57.59399  ? 169 TYR A OH  1 
ATOM   1300 N  N   . LEU A 1 170 ? 68.91758  -20.84164 -23.66721 1.000 61.31211  ? 170 LEU A N   1 
ATOM   1301 C  CA  . LEU A 1 170 ? 69.93942  -20.60835 -22.65158 1.000 55.39775  ? 170 LEU A CA  1 
ATOM   1302 C  C   . LEU A 1 170 ? 70.81803  -21.83825 -22.45910 1.000 66.51869  ? 170 LEU A C   1 
ATOM   1303 O  O   . LEU A 1 170 ? 72.04889  -21.73429 -22.40383 1.000 61.69228  ? 170 LEU A O   1 
ATOM   1304 C  CB  . LEU A 1 170 ? 69.27885  -20.20955 -21.33263 1.000 57.56924  ? 170 LEU A CB  1 
ATOM   1305 C  CG  . LEU A 1 170 ? 68.44610  -18.92656 -21.33909 1.000 57.60342  ? 170 LEU A CG  1 
ATOM   1306 C  CD1 . LEU A 1 170 ? 67.68598  -18.77761 -20.03050 1.000 66.69166  ? 170 LEU A CD1 1 
ATOM   1307 C  CD2 . LEU A 1 170 ? 69.32566  -17.71342 -21.58898 1.000 57.20577  ? 170 LEU A CD2 1 
ATOM   1308 N  N   . ALA A 1 171 ? 70.19645  -23.01988 -22.37329 1.000 62.14053  ? 171 ALA A N   1 
ATOM   1309 C  CA  . ALA A 1 171 ? 70.95825  -24.25307 -22.20161 1.000 60.14956  ? 171 ALA A CA  1 
ATOM   1310 C  C   . ALA A 1 171 ? 71.99484  -24.43450 -23.30227 1.000 70.28338  ? 171 ALA A C   1 
ATOM   1311 O  O   . ALA A 1 171 ? 73.02535  -25.08298 -23.08541 1.000 70.53889  ? 171 ALA A O   1 
ATOM   1312 C  CB  . ALA A 1 171 ? 70.01231  -25.45157 -22.15854 1.000 68.95125  ? 171 ALA A CB  1 
ATOM   1313 N  N   . MET A 1 172 ? 71.74495  -23.86994 -24.48211 1.000 59.76538  ? 172 MET A N   1 
ATOM   1314 C  CA  . MET A 1 172 ? 72.71397  -23.90113 -25.56864 1.000 60.37045  ? 172 MET A CA  1 
ATOM   1315 C  C   . MET A 1 172 ? 73.55926  -22.63368 -25.62377 1.000 58.79545  ? 172 MET A C   1 
ATOM   1316 O  O   . MET A 1 172 ? 74.78125  -22.71122 -25.79440 1.000 57.69608  ? 172 MET A O   1 
ATOM   1317 C  CB  . MET A 1 172 ? 71.99593  -24.10941 -26.90555 1.000 63.79763  ? 172 MET A CB  1 
ATOM   1318 C  CG  . MET A 1 172 ? 72.91377  -24.13478 -28.11935 1.000 65.01352  ? 172 MET A CG  1 
ATOM   1319 S  SD  . MET A 1 172 ? 72.03402  -24.50754 -29.65486 1.000 70.57378  ? 172 MET A SD  1 
ATOM   1320 C  CE  . MET A 1 172 ? 70.93835  -23.09508 -29.76727 1.000 63.50334  ? 172 MET A CE  1 
ATOM   1321 N  N   . ARG A 1 173 ? 72.93122  -21.46524 -25.47069 1.000 52.77354  ? 173 ARG A N   1 
ATOM   1322 C  CA  . ARG A 1 173 ? 73.64182  -20.20030 -25.62099 1.000 55.72935  ? 173 ARG A CA  1 
ATOM   1323 C  C   . ARG A 1 173 ? 74.59267  -19.91912 -24.46416 1.000 51.66235  ? 173 ARG A C   1 
ATOM   1324 O  O   . ARG A 1 173 ? 75.56623  -19.17985 -24.64806 1.000 54.87863  ? 173 ARG A O   1 
ATOM   1325 C  CB  . ARG A 1 173 ? 72.63956  -19.05226 -25.76552 1.000 54.01724  ? 173 ARG A CB  1 
ATOM   1326 C  CG  . ARG A 1 173 ? 73.26180  -17.71819 -26.14649 1.000 55.93393  ? 173 ARG A CG  1 
ATOM   1327 C  CD  . ARG A 1 173 ? 73.81069  -17.73658 -27.56489 1.000 56.64811  ? 173 ARG A CD  1 
ATOM   1328 N  NE  . ARG A 1 173 ? 74.30296  -16.42509 -27.97293 1.000 62.71552  ? 173 ARG A NE  1 
ATOM   1329 C  CZ  . ARG A 1 173 ? 75.54385  -16.17000 -28.36890 1.000 62.05399  ? 173 ARG A CZ  1 
ATOM   1330 N  NH1 . ARG A 1 173 ? 76.45213  -17.12822 -28.46711 1.000 55.96501  ? 173 ARG A NH1 1 
ATOM   1331 N  NH2 . ARG A 1 173 ? 75.87877  -14.92273 -28.68733 1.000 63.31327  ? 173 ARG A NH2 1 
ATOM   1332 N  N   . ARG A 1 174 ? 74.34324  -20.49304 -23.28415 1.000 50.13728  ? 174 ARG A N   1 
ATOM   1333 C  CA  . ARG A 1 174 ? 75.23107  -20.26264 -22.15020 1.000 53.07805  ? 174 ARG A CA  1 
ATOM   1334 C  C   . ARG A 1 174 ? 76.63708  -20.78596 -22.40103 1.000 51.18885  ? 174 ARG A C   1 
ATOM   1335 O  O   . ARG A 1 174 ? 77.57567  -20.35497 -21.72334 1.000 55.00719  ? 174 ARG A O   1 
ATOM   1336 C  CB  . ARG A 1 174 ? 74.65480  -20.90003 -20.88397 1.000 48.20824  ? 174 ARG A CB  1 
ATOM   1337 C  CG  . ARG A 1 174 ? 73.55783  -20.07391 -20.23659 1.000 51.33531  ? 174 ARG A CG  1 
ATOM   1338 C  CD  . ARG A 1 174 ? 72.73272  -20.88255 -19.24652 1.000 54.09214  ? 174 ARG A CD  1 
ATOM   1339 N  NE  . ARG A 1 174 ? 71.85438  -20.01896 -18.46621 1.000 57.78767  ? 174 ARG A NE  1 
ATOM   1340 C  CZ  . ARG A 1 174 ? 70.89093  -20.45145 -17.66472 1.000 61.11912  ? 174 ARG A CZ  1 
ATOM   1341 N  NH1 . ARG A 1 174 ? 70.63610  -21.74151 -17.52351 1.000 60.83236  ? 174 ARG A NH1 1 
ATOM   1342 N  NH2 . ARG A 1 174 ? 70.16161  -19.56647 -16.99125 1.000 54.94135  ? 174 ARG A NH2 1 
ATOM   1343 N  N   . HIS A 1 175 ? 76.80694  -21.69655 -23.35824 1.000 49.27989  ? 175 HIS A N   1 
ATOM   1344 C  CA  . HIS A 1 175 ? 78.12904  -22.21243 -23.69157 1.000 52.53050  ? 175 HIS A CA  1 
ATOM   1345 C  C   . HIS A 1 175 ? 78.76490  -21.47595 -24.86610 1.000 52.98845  ? 175 HIS A C   1 
ATOM   1346 O  O   . HIS A 1 175 ? 79.96981  -21.20348 -24.84248 1.000 52.24210  ? 175 HIS A O   1 
ATOM   1347 C  CB  . HIS A 1 175 ? 78.04597  -23.71125 -23.99175 1.000 47.84563  ? 175 HIS A CB  1 
ATOM   1348 C  CG  . HIS A 1 175 ? 77.55279  -24.52661 -22.83881 1.000 54.72562  ? 175 HIS A CG  1 
ATOM   1349 N  ND1 . HIS A 1 175 ? 78.28949  -24.70873 -21.68815 1.000 57.86781  ? 175 HIS A ND1 1 
ATOM   1350 C  CD2 . HIS A 1 175 ? 76.39325  -25.20084 -22.65384 1.000 58.23287  ? 175 HIS A CD2 1 
ATOM   1351 C  CE1 . HIS A 1 175 ? 77.60653  -25.46314 -20.84551 1.000 53.50411  ? 175 HIS A CE1 1 
ATOM   1352 N  NE2 . HIS A 1 175 ? 76.45220  -25.77510 -21.40703 1.000 60.25470  ? 175 HIS A NE2 1 
ATOM   1353 N  N   . THR A 1 176 ? 77.97950  -21.13532 -25.89053 1.000 46.34966  ? 176 THR A N   1 
ATOM   1354 C  CA  . THR A 1 176 ? 78.53234  -20.45645 -27.05804 1.000 53.46447  ? 176 THR A CA  1 
ATOM   1355 C  C   . THR A 1 176 ? 78.85532  -18.99132 -26.79216 1.000 56.95500  ? 176 THR A C   1 
ATOM   1356 O  O   . THR A 1 176 ? 79.62520  -18.39419 -27.55246 1.000 56.53141  ? 176 THR A O   1 
ATOM   1357 C  CB  . THR A 1 176 ? 77.56135  -20.55656 -28.23336 1.000 56.33091  ? 176 THR A CB  1 
ATOM   1358 O  OG1 . THR A 1 176 ? 76.28754  -20.02395 -27.84567 1.000 54.77003  ? 176 THR A OG1 1 
ATOM   1359 C  CG2 . THR A 1 176 ? 77.39196  -22.00309 -28.64513 1.000 53.77101  ? 176 THR A CG2 1 
ATOM   1360 N  N   . ILE A 1 177 ? 78.29037  -18.39898 -25.73666 1.000 52.67709  ? 177 ILE A N   1 
ATOM   1361 C  CA  . ILE A 1 177 ? 78.52284  -16.98471 -25.46837 1.000 50.32576  ? 177 ILE A CA  1 
ATOM   1362 C  C   . ILE A 1 177 ? 79.96318  -16.72019 -25.03402 1.000 53.12354  ? 177 ILE A C   1 
ATOM   1363 O  O   . ILE A 1 177 ? 80.42858  -15.57724 -25.10563 1.000 51.90199  ? 177 ILE A O   1 
ATOM   1364 C  CB  . ILE A 1 177 ? 77.51086  -16.48261 -24.41943 1.000 52.43920  ? 177 ILE A CB  1 
ATOM   1365 C  CG1 . ILE A 1 177 ? 77.49506  -14.95192 -24.35633 1.000 59.24009  ? 177 ILE A CG1 1 
ATOM   1366 C  CG2 . ILE A 1 177 ? 77.80998  -17.08516 -23.05348 1.000 51.05249  ? 177 ILE A CG2 1 
ATOM   1367 C  CD1 . ILE A 1 177 ? 77.00905  -14.28847 -25.63049 1.000 56.89773  ? 177 ILE A CD1 1 
ATOM   1368 N  N   . GLY A 1 178 ? 80.68679  -17.74781 -24.58962 1.000 48.56567  ? 178 GLY A N   1 
ATOM   1369 C  CA  . GLY A 1 178 ? 82.10452  -17.61307 -24.30459 1.000 43.06250  ? 178 GLY A CA  1 
ATOM   1370 C  C   . GLY A 1 178 ? 82.45649  -16.80530 -23.07423 1.000 44.39300  ? 178 GLY A C   1 
ATOM   1371 O  O   . GLY A 1 178 ? 83.58904  -16.32841 -22.96242 1.000 40.62632  ? 178 GLY A O   1 
ATOM   1372 N  N   . VAL A 1 179 ? 81.52521  -16.64813 -22.13352 1.000 38.01880  ? 179 VAL A N   1 
ATOM   1373 C  CA  . VAL A 1 179 ? 81.79579  -15.81975 -20.96222 1.000 41.69209  ? 179 VAL A CA  1 
ATOM   1374 C  C   . VAL A 1 179 ? 82.78329  -16.50520 -20.02116 1.000 42.55373  ? 179 VAL A C   1 
ATOM   1375 O  O   . VAL A 1 179 ? 83.71155  -15.86949 -19.50536 1.000 38.12670  ? 179 VAL A O   1 
ATOM   1376 C  CB  . VAL A 1 179 ? 80.47924  -15.47062 -20.24940 1.000 45.89187  ? 179 VAL A CB  1 
ATOM   1377 C  CG1 . VAL A 1 179 ? 80.76011  -14.84838 -18.88576 1.000 40.56517  ? 179 VAL A CG1 1 
ATOM   1378 C  CG2 . VAL A 1 179 ? 79.65919  -14.53191 -21.11372 1.000 43.80887  ? 179 VAL A CG2 1 
ATOM   1379 N  N   . GLN A 1 180 ? 82.60704  -17.80449 -19.77974 1.000 37.80016  ? 180 GLN A N   1 
ATOM   1380 C  CA  . GLN A 1 180 ? 83.47332  -18.48495 -18.81808 1.000 39.32704  ? 180 GLN A CA  1 
ATOM   1381 C  C   . GLN A 1 180 ? 84.93620  -18.48699 -19.24228 1.000 35.63406  ? 180 GLN A C   1 
ATOM   1382 O  O   . GLN A 1 180 ? 85.79629  -18.19291 -18.39405 1.000 38.47005  ? 180 GLN A O   1 
ATOM   1383 C  CB  . GLN A 1 180 ? 82.96238  -19.90591 -18.55723 1.000 42.22294  ? 180 GLN A CB  1 
ATOM   1384 C  CG  . GLN A 1 180 ? 83.67002  -20.59510 -17.39941 1.000 40.88788  ? 180 GLN A CG  1 
ATOM   1385 C  CD  . GLN A 1 180 ? 83.57287  -19.80037 -16.10738 1.000 42.90545  ? 180 GLN A CD  1 
ATOM   1386 O  OE1 . GLN A 1 180 ? 82.47935  -19.49394 -15.63736 1.000 40.02819  ? 180 GLN A OE1 1 
ATOM   1387 N  NE2 . GLN A 1 180 ? 84.72131  -19.45007 -15.53568 1.000 36.50490  ? 180 GLN A NE2 1 
ATOM   1388 N  N   . PRO A 1 181 ? 85.29867  -18.79564 -20.49580 1.000 36.71082  ? 181 PRO A N   1 
ATOM   1389 C  CA  . PRO A 1 181 ? 86.71049  -18.64529 -20.88703 1.000 35.37072  ? 181 PRO A CA  1 
ATOM   1390 C  C   . PRO A 1 181 ? 87.21600  -17.22138 -20.75131 1.000 33.19678  ? 181 PRO A C   1 
ATOM   1391 O  O   . PRO A 1 181 ? 88.40796  -17.01813 -20.49035 1.000 33.96908  ? 181 PRO A O   1 
ATOM   1392 C  CB  . PRO A 1 181 ? 86.72298  -19.11114 -22.35057 1.000 35.41052  ? 181 PRO A CB  1 
ATOM   1393 C  CG  . PRO A 1 181 ? 85.54785  -19.99874 -22.47031 1.000 35.90755  ? 181 PRO A CG  1 
ATOM   1394 C  CD  . PRO A 1 181 ? 84.50323  -19.39380 -21.58338 1.000 39.02199  ? 181 PRO A CD  1 
ATOM   1395 N  N   . THR A 1 182 ? 86.34181  -16.22821 -20.93201 1.000 31.64088  ? 182 THR A N   1 
ATOM   1396 C  CA  . THR A 1 182 ? 86.73072  -14.83771 -20.71397 1.000 37.20128  ? 182 THR A CA  1 
ATOM   1397 C  C   . THR A 1 182 ? 87.02117  -14.57101 -19.23992 1.000 37.19147  ? 182 THR A C   1 
ATOM   1398 O  O   . THR A 1 182 ? 88.01640  -13.91704 -18.90615 1.000 35.13601  ? 182 THR A O   1 
ATOM   1399 C  CB  . THR A 1 182 ? 85.63084  -13.90108 -21.22338 1.000 38.53496  ? 182 THR A CB  1 
ATOM   1400 O  OG1 . THR A 1 182 ? 85.47015  -14.06501 -22.63803 1.000 36.92403  ? 182 THR A OG1 1 
ATOM   1401 C  CG2 . THR A 1 182 ? 85.97311  -12.45491 -20.92439 1.000 40.39953  ? 182 THR A CG2 1 
ATOM   1402 N  N   . VAL A 1 183 ? 86.16818  -15.07788 -18.34483 1.000 34.88030  ? 183 VAL A N   1 
ATOM   1403 C  CA  . VAL A 1 183 ? 86.39465  -14.90353 -16.91108 1.000 35.62406  ? 183 VAL A CA  1 
ATOM   1404 C  C   . VAL A 1 183 ? 87.66542  -15.62469 -16.48071 1.000 35.62395  ? 183 VAL A C   1 
ATOM   1405 O  O   . VAL A 1 183 ? 88.45905  -15.09412 -15.69465 1.000 36.71479  ? 183 VAL A O   1 
ATOM   1406 C  CB  . VAL A 1 183 ? 85.16679  -15.38367 -16.11321 1.000 35.38425  ? 183 VAL A CB  1 
ATOM   1407 C  CG1 . VAL A 1 183 ? 85.48174  -15.44934 -14.63204 1.000 35.93739  ? 183 VAL A CG1 1 
ATOM   1408 C  CG2 . VAL A 1 183 ? 83.98556  -14.46254 -16.35986 1.000 37.06870  ? 183 VAL A CG2 1 
ATOM   1409 N  N   . ASP A 1 184 ? 87.88249  -16.84055 -16.99399 1.000 34.60119  ? 184 ASP A N   1 
ATOM   1410 C  CA  . ASP A 1 184 ? 89.10441  -17.57725 -16.68308 1.000 32.11523  ? 184 ASP A CA  1 
ATOM   1411 C  C   . ASP A 1 184 ? 90.34228  -16.74637 -16.98447 1.000 35.93773  ? 184 ASP A C   1 
ATOM   1412 O  O   . ASP A 1 184 ? 91.29721  -16.73279 -16.20064 1.000 34.51215  ? 184 ASP A O   1 
ATOM   1413 C  CB  . ASP A 1 184 ? 89.15522  -18.88630 -17.47522 1.000 34.57297  ? 184 ASP A CB  1 
ATOM   1414 C  CG  . ASP A 1 184 ? 88.04977  -19.85252 -17.09295 1.000 44.42787  ? 184 ASP A CG  1 
ATOM   1415 O  OD1 . ASP A 1 184 ? 87.42040  -19.66963 -16.02520 1.000 36.92983  ? 184 ASP A OD1 1 
ATOM   1416 O  OD2 . ASP A 1 184 ? 87.81967  -20.81129 -17.86169 1.000 38.55588  ? 184 ASP A OD2 1 
ATOM   1417 N  N   . LEU A 1 185 ? 90.34423  -16.04350 -18.11994 1.000 36.22010  ? 185 LEU A N   1 
ATOM   1418 C  CA  . LEU A 1 185 ? 91.52034  -15.26737 -18.49341 1.000 35.34984  ? 185 LEU A CA  1 
ATOM   1419 C  C   . LEU A 1 185 ? 91.73544  -14.08086 -17.56008 1.000 32.17338  ? 185 LEU A C   1 
ATOM   1420 O  O   . LEU A 1 185 ? 92.87563  -13.64215 -17.37301 1.000 33.39065  ? 185 LEU A O   1 
ATOM   1421 C  CB  . LEU A 1 185 ? 91.40173  -14.79337 -19.93901 1.000 33.26985  ? 185 LEU A CB  1 
ATOM   1422 C  CG  . LEU A 1 185 ? 92.74341  -14.36316 -20.53051 1.000 37.46762  ? 185 LEU A CG  1 
ATOM   1423 C  CD1 . LEU A 1 185 ? 93.57145  -15.57666 -20.91223 1.000 42.85508  ? 185 LEU A CD1 1 
ATOM   1424 C  CD2 . LEU A 1 185 ? 92.52221  -13.49761 -21.72190 1.000 51.23783  ? 185 LEU A CD2 1 
ATOM   1425 N  N   . ALA A 1 186 ? 90.66304  -13.54411 -16.97416 1.000 30.82238  ? 186 ALA A N   1 
ATOM   1426 C  CA  . ALA A 1 186 ? 90.82719  -12.48320 -15.98515 1.000 34.74094  ? 186 ALA A CA  1 
ATOM   1427 C  C   . ALA A 1 186 ? 91.67474  -12.95679 -14.81253 1.000 35.28013  ? 186 ALA A C   1 
ATOM   1428 O  O   . ALA A 1 186 ? 92.48824  -12.19438 -14.27959 1.000 35.11778  ? 186 ALA A O   1 
ATOM   1429 C  CB  . ALA A 1 186 ? 89.46312  -11.99501 -15.50263 1.000 29.79036  ? 186 ALA A CB  1 
ATOM   1430 N  N   . GLU A 1 187 ? 91.50655  -14.21919 -14.40613 1.000 37.94169  ? 187 GLU A N   1 
ATOM   1431 C  CA  . GLU A 1 187 ? 92.35741  -14.79376 -13.36642 1.000 35.27374  ? 187 GLU A CA  1 
ATOM   1432 C  C   . GLU A 1 187 ? 93.80621  -14.85595 -13.82208 1.000 36.84788  ? 187 GLU A C   1 
ATOM   1433 O  O   . GLU A 1 187 ? 94.71491  -14.41999 -13.10690 1.000 35.90319  ? 187 GLU A O   1 
ATOM   1434 C  CB  . GLU A 1 187 ? 91.87220  -16.19510 -12.99997 1.000 34.64981  ? 187 GLU A CB  1 
ATOM   1435 C  CG  . GLU A 1 187 ? 90.57349  -16.24772 -12.23544 1.000 37.20722  ? 187 GLU A CG  1 
ATOM   1436 C  CD  . GLU A 1 187 ? 90.22947  -17.66225 -11.81197 1.000 44.97553  ? 187 GLU A CD  1 
ATOM   1437 O  OE1 . GLU A 1 187 ? 89.79218  -18.45524 -12.67396 1.000 44.26663  ? 187 GLU A OE1 1 
ATOM   1438 O  OE2 . GLU A 1 187 ? 90.41766  -17.98579 -10.62085 1.000 40.20107  ? 187 GLU A OE2 1 
ATOM   1439 N  N   . ARG A 1 188 ? 94.03856  -15.41698 -15.00989 1.000 34.78180  ? 188 ARG A N   1 
ATOM   1440 C  CA  . ARG A 1 188 ? 95.39139  -15.49635 -15.54515 1.000 36.82248  ? 188 ARG A CA  1 
ATOM   1441 C  C   . ARG A 1 188 ? 95.98913  -14.10751 -15.73712 1.000 38.59316  ? 188 ARG A C   1 
ATOM   1442 O  O   . ARG A 1 188 ? 97.15785  -13.87547 -15.40711 1.000 39.15689  ? 188 ARG A O   1 
ATOM   1443 C  CB  . ARG A 1 188 ? 95.37323  -16.27216 -16.86369 1.000 34.02322  ? 188 ARG A CB  1 
ATOM   1444 C  CG  . ARG A 1 188 ? 96.59607  -16.06503 -17.73957 1.000 35.71108  ? 188 ARG A CG  1 
ATOM   1445 C  CD  . ARG A 1 188 ? 97.86870  -16.57684 -17.08313 1.000 33.72261  ? 188 ARG A CD  1 
ATOM   1446 N  NE  . ARG A 1 188 ? 99.01875  -16.39738 -17.96067 1.000 38.23747  ? 188 ARG A NE  1 
ATOM   1447 C  CZ  . ARG A 1 188 ? 99.67464  -15.25342 -18.10836 1.000 43.82323  ? 188 ARG A CZ  1 
ATOM   1448 N  NH1 . ARG A 1 188 ? 99.32863  -14.16473 -17.43873 1.000 39.18973  ? 188 ARG A NH1 1 
ATOM   1449 N  NH2 . ARG A 1 188 ? 100.70266 -15.19882 -18.94984 1.000 41.07477  ? 188 ARG A NH2 1 
ATOM   1450 N  N   . ALA A 1 189 ? 95.19995  -13.16758 -16.26743 1.000 36.52329  ? 189 ALA A N   1 
ATOM   1451 C  CA  . ALA A 1 189 ? 95.70730  -11.81690 -16.48776 1.000 40.92190  ? 189 ALA A CA  1 
ATOM   1452 C  C   . ALA A 1 189 ? 95.99749  -11.10623 -15.17163 1.000 36.42917  ? 189 ALA A C   1 
ATOM   1453 O  O   . ALA A 1 189 ? 96.88727  -10.25060 -15.11412 1.000 40.85024  ? 189 ALA A O   1 
ATOM   1454 C  CB  . ALA A 1 189 ? 94.71533  -11.01137 -17.33004 1.000 31.73886  ? 189 ALA A CB  1 
ATOM   1455 N  N   . GLY A 1 190 ? 95.26779  -11.44465 -14.11215 1.000 37.36133  ? 190 GLY A N   1 
ATOM   1456 C  CA  . GLY A 1 190 ? 95.50251  -10.89201 -12.79678 1.000 35.67813  ? 190 GLY A CA  1 
ATOM   1457 C  C   . GLY A 1 190 ? 96.44540  -11.68932 -11.92784 1.000 40.76883  ? 190 GLY A C   1 
ATOM   1458 O  O   . GLY A 1 190 ? 96.75699  -11.26125 -10.81225 1.000 36.94222  ? 190 GLY A O   1 
ATOM   1459 N  N   . ARG A 1 191 ? 96.89931  -12.84967 -12.40551 1.000 38.92794  ? 191 ARG A N   1 
ATOM   1460 C  CA  . ARG A 1 191 ? 97.85907  -13.68901 -11.68550 1.000 40.65078  ? 191 ARG A CA  1 
ATOM   1461 C  C   . ARG A 1 191 ? 97.32860  -14.09810 -10.31230 1.000 41.06048  ? 191 ARG A C   1 
ATOM   1462 O  O   . ARG A 1 191 ? 98.05069  -14.08979 -9.31387  1.000 38.07080  ? 191 ARG A O   1 
ATOM   1463 C  CB  . ARG A 1 191 ? 99.22103  -12.99564 -11.58352 1.000 38.50036  ? 191 ARG A CB  1 
ATOM   1464 C  CG  . ARG A 1 191 ? 99.85552  -12.80392 -12.96174 1.000 39.56737  ? 191 ARG A CG  1 
ATOM   1465 C  CD  . ARG A 1 191 ? 101.12958 -11.97472 -12.93986 1.000 48.95446  ? 191 ARG A CD  1 
ATOM   1466 N  NE  . ARG A 1 191 ? 101.64709 -11.77693 -14.29026 1.000 49.63931  ? 191 ARG A NE  1 
ATOM   1467 C  CZ  . ARG A 1 191 ? 102.77300 -12.30493 -14.75371 1.000 55.10651  ? 191 ARG A CZ  1 
ATOM   1468 N  NH1 . ARG A 1 191 ? 103.57554 -13.01692 -13.97889 1.000 50.21012  ? 191 ARG A NH1 1 
ATOM   1469 N  NH2 . ARG A 1 191 ? 103.10464 -12.11049 -16.02714 1.000 48.23224  ? 191 ARG A NH2 1 
ATOM   1470 N  N   . PHE A 1 192 ? 96.04937  -14.46240 -10.26584 1.000 35.60561  ? 192 PHE A N   1 
ATOM   1471 C  CA  . PHE A 1 192 ? 95.43838  -15.01202 -9.06789  1.000 38.23995  ? 192 PHE A CA  1 
ATOM   1472 C  C   . PHE A 1 192 ? 94.50102  -16.13111 -9.48795  1.000 38.89483  ? 192 PHE A C   1 
ATOM   1473 O  O   . PHE A 1 192 ? 94.11580  -16.23693 -10.65399 1.000 36.99520  ? 192 PHE A O   1 
ATOM   1474 C  CB  . PHE A 1 192 ? 94.67092  -13.94754 -8.26284  1.000 31.26112  ? 192 PHE A CB  1 
ATOM   1475 C  CG  . PHE A 1 192 ? 93.43568  -13.42540 -8.95961  1.000 39.49231  ? 192 PHE A CG  1 
ATOM   1476 C  CD1 . PHE A 1 192 ? 93.52928  -12.40205 -9.88786  1.000 39.12163  ? 192 PHE A CD1 1 
ATOM   1477 C  CD2 . PHE A 1 192 ? 92.18185  -13.94962 -8.67694  1.000 38.43720  ? 192 PHE A CD2 1 
ATOM   1478 C  CE1 . PHE A 1 192 ? 92.39813  -11.91499 -10.52834 1.000 36.33194  ? 192 PHE A CE1 1 
ATOM   1479 C  CE2 . PHE A 1 192 ? 91.04644  -13.46702 -9.31269  1.000 38.58319  ? 192 PHE A CE2 1 
ATOM   1480 C  CZ  . PHE A 1 192 ? 91.15524  -12.44786 -10.23971 1.000 36.04069  ? 192 PHE A CZ  1 
ATOM   1481 N  N   . GLU A 1 193 ? 94.13612  -16.96979 -8.52154  1.000 37.98067  ? 193 GLU A N   1 
ATOM   1482 C  CA  . GLU A 1 193 ? 93.15392  -18.02476 -8.72742  1.000 34.48528  ? 193 GLU A CA  1 
ATOM   1483 C  C   . GLU A 1 193 ? 92.15264  -17.98470 -7.58442  1.000 42.99567  ? 193 GLU A C   1 
ATOM   1484 O  O   . GLU A 1 193 ? 92.54186  -18.06002 -6.41462  1.000 37.09313  ? 193 GLU A O   1 
ATOM   1485 C  CB  . GLU A 1 193 ? 93.81974  -19.40410 -8.80268  1.000 35.76765  ? 193 GLU A CB  1 
ATOM   1486 C  CG  . GLU A 1 193 ? 94.77511  -19.57291 -9.97486  1.000 36.92922  ? 193 GLU A CG  1 
ATOM   1487 C  CD  . GLU A 1 193 ? 95.44140  -20.94007 -10.00898 1.000 39.35211  ? 193 GLU A CD  1 
ATOM   1488 O  OE1 . GLU A 1 193 ? 94.83005  -21.92594 -9.54076  1.000 35.57810  ? 193 GLU A OE1 1 
ATOM   1489 O  OE2 . GLU A 1 193 ? 96.58391  -21.02580 -10.50705 1.000 38.73508  ? 193 GLU A OE2 1 
ATOM   1490 N  N   . VAL A 1 194 ? 90.87251  -17.85045 -7.92046  1.000 36.19018  ? 194 VAL A N   1 
ATOM   1491 C  CA  . VAL A 1 194 ? 89.84567  -17.94761 -6.87874  1.000 38.91070  ? 194 VAL A CA  1 
ATOM   1492 C  C   . VAL A 1 194 ? 89.92304  -19.33333 -6.24960  1.000 45.55564  ? 194 VAL A C   1 
ATOM   1493 O  O   . VAL A 1 194 ? 90.19076  -20.32036 -6.96785  1.000 40.88920  ? 194 VAL A O   1 
ATOM   1494 C  CB  . VAL A 1 194 ? 88.44692  -17.67302 -7.46581  1.000 41.38880  ? 194 VAL A CB  1 
ATOM   1495 C  CG1 . VAL A 1 194 ? 88.05434  -18.74190 -8.47901  1.000 37.34795  ? 194 VAL A CG1 1 
ATOM   1496 C  CG2 . VAL A 1 194 ? 87.39477  -17.54236 -6.36550  1.000 34.00979  ? 194 VAL A CG2 1 
ATOM   1497 N  N   . PRO A 1 195 ? 89.76967  -19.47060 -4.93105  1.000 42.21383  ? 195 PRO A N   1 
ATOM   1498 C  CA  . PRO A 1 195 ? 89.82660  -20.80301 -4.31522  1.000 41.10262  ? 195 PRO A CA  1 
ATOM   1499 C  C   . PRO A 1 195 ? 88.91452  -21.78034 -5.03691  1.000 39.93436  ? 195 PRO A C   1 
ATOM   1500 O  O   . PRO A 1 195 ? 87.73676  -21.50053 -5.27612  1.000 39.49085  ? 195 PRO A O   1 
ATOM   1501 C  CB  . PRO A 1 195 ? 89.36624  -20.54534 -2.87746  1.000 43.21906  ? 195 PRO A CB  1 
ATOM   1502 C  CG  . PRO A 1 195 ? 89.79950  -19.14715 -2.60850  1.000 41.18473  ? 195 PRO A CG  1 
ATOM   1503 C  CD  . PRO A 1 195 ? 89.66238  -18.40363 -3.92039  1.000 44.86323  ? 195 PRO A CD  1 
ATOM   1504 N  N   . HIS A 1 196 ? 89.48196  -22.93024 -5.40823  1.000 37.16677  ? 196 HIS A N   1 
ATOM   1505 C  CA  . HIS A 1 196 ? 88.79417  -23.82802 -6.32851  1.000 35.47078  ? 196 HIS A CA  1 
ATOM   1506 C  C   . HIS A 1 196 ? 87.50818  -24.37232 -5.72433  1.000 39.67764  ? 196 HIS A C   1 
ATOM   1507 O  O   . HIS A 1 196 ? 86.50873  -24.53957 -6.43271  1.000 36.46322  ? 196 HIS A O   1 
ATOM   1508 C  CB  . HIS A 1 196 ? 89.72959  -24.96204 -6.74624  1.000 39.16103  ? 196 HIS A CB  1 
ATOM   1509 C  CG  . HIS A 1 196 ? 90.89984  -24.50403 -7.55967  1.000 43.66127  ? 196 HIS A CG  1 
ATOM   1510 N  ND1 . HIS A 1 196 ? 91.79511  -25.37871 -8.13629  1.000 42.95723  ? 196 HIS A ND1 1 
ATOM   1511 C  CD2 . HIS A 1 196 ? 91.31908  -23.26058 -7.89568  1.000 42.59648  ? 196 HIS A CD2 1 
ATOM   1512 C  CE1 . HIS A 1 196 ? 92.71538  -24.69439 -8.79236  1.000 45.64033  ? 196 HIS A CE1 1 
ATOM   1513 N  NE2 . HIS A 1 196 ? 92.44964  -23.40682 -8.66228  1.000 47.05932  ? 196 HIS A NE2 1 
ATOM   1514 N  N   . ARG A 1 197 ? 87.50176  -24.64112 -4.41423  1.000 35.54756  ? 197 ARG A N   1 
ATOM   1515 C  CA  . ARG A 1 197 ? 86.27325  -25.11890 -3.79376  1.000 39.79915  ? 197 ARG A CA  1 
ATOM   1516 C  C   . ARG A 1 197 ? 85.19144  -24.04607 -3.77133  1.000 39.13430  ? 197 ARG A C   1 
ATOM   1517 O  O   . ARG A 1 197 ? 84.00461  -24.38180 -3.69329  1.000 39.55534  ? 197 ARG A O   1 
ATOM   1518 C  CB  . ARG A 1 197 ? 86.55200  -25.63661 -2.37902  1.000 39.76855  ? 197 ARG A CB  1 
ATOM   1519 C  CG  . ARG A 1 197 ? 87.07623  -24.60709 -1.37583  1.000 40.36740  ? 197 ARG A CG  1 
ATOM   1520 C  CD  . ARG A 1 197 ? 87.66567  -25.33701 -0.16304  1.000 40.47460  ? 197 ARG A CD  1 
ATOM   1521 N  NE  . ARG A 1 197 ? 88.06411  -24.45335 0.92657   1.000 41.23033  ? 197 ARG A NE  1 
ATOM   1522 C  CZ  . ARG A 1 197 ? 89.21244  -23.79249 0.97370   1.000 43.86178  ? 197 ARG A CZ  1 
ATOM   1523 N  NH1 . ARG A 1 197 ? 90.07421  -23.83148 -0.02920  1.000 41.48028  ? 197 ARG A NH1 1 
ATOM   1524 N  NH2 . ARG A 1 197 ? 89.50315  -23.07298 2.05376   1.000 39.94468  ? 197 ARG A NH2 1 
ATOM   1525 N  N   . VAL A 1 198 ? 85.56719  -22.77125 -3.85326  1.000 32.65485  ? 198 VAL A N   1 
ATOM   1526 C  CA  . VAL A 1 198 ? 84.57050  -21.70805 -3.90778  1.000 33.47498  ? 198 VAL A CA  1 
ATOM   1527 C  C   . VAL A 1 198 ? 84.08933  -21.46784 -5.33863  1.000 40.08579  ? 198 VAL A C   1 
ATOM   1528 O  O   . VAL A 1 198 ? 82.92295  -21.11394 -5.54569  1.000 33.77947  ? 198 VAL A O   1 
ATOM   1529 C  CB  . VAL A 1 198 ? 85.12448  -20.41690 -3.27531  1.000 42.17403  ? 198 VAL A CB  1 
ATOM   1530 C  CG1 . VAL A 1 198 ? 84.13642  -19.27133 -3.42577  1.000 39.36287  ? 198 VAL A CG1 1 
ATOM   1531 C  CG2 . VAL A 1 198 ? 85.44310  -20.64310 -1.80042  1.000 40.64402  ? 198 VAL A CG2 1 
ATOM   1532 N  N   . PHE A 1 199 ? 84.95603  -21.67089 -6.33741  1.000 38.74318  ? 199 PHE A N   1 
ATOM   1533 C  CA  . PHE A 1 199 ? 84.49553  -21.62393 -7.72270  1.000 37.59291  ? 199 PHE A CA  1 
ATOM   1534 C  C   . PHE A 1 199 ? 83.34020  -22.59120 -7.94513  1.000 36.65950  ? 199 PHE A C   1 
ATOM   1535 O  O   . PHE A 1 199 ? 82.36783  -22.26126 -8.63229  1.000 39.68831  ? 199 PHE A O   1 
ATOM   1536 C  CB  . PHE A 1 199 ? 85.64418  -21.93879 -8.68724  1.000 37.00112  ? 199 PHE A CB  1 
ATOM   1537 C  CG  . PHE A 1 199 ? 85.22149  -21.97910 -10.13843 1.000 44.68859  ? 199 PHE A CG  1 
ATOM   1538 C  CD1 . PHE A 1 199 ? 84.73269  -23.15007 -10.70829 1.000 36.58575  ? 199 PHE A CD1 1 
ATOM   1539 C  CD2 . PHE A 1 199 ? 85.30269  -20.84257 -10.92956 1.000 38.34181  ? 199 PHE A CD2 1 
ATOM   1540 C  CE1 . PHE A 1 199 ? 84.33135  -23.18266 -12.03489 1.000 42.10497  ? 199 PHE A CE1 1 
ATOM   1541 C  CE2 . PHE A 1 199 ? 84.90809  -20.87274 -12.25915 1.000 41.36666  ? 199 PHE A CE2 1 
ATOM   1542 C  CZ  . PHE A 1 199 ? 84.42196  -22.04285 -12.80982 1.000 41.29705  ? 199 PHE A CZ  1 
ATOM   1543 N  N   . ASP A 1 200 ? 83.42783  -23.78932 -7.36283  1.000 38.66323  ? 200 ASP A N   1 
ATOM   1544 C  CA  . ASP A 1 200 ? 82.39029  -24.80551 -7.49383  1.000 43.08050  ? 200 ASP A CA  1 
ATOM   1545 C  C   . ASP A 1 200 ? 81.17343  -24.54906 -6.61279  1.000 41.32426  ? 200 ASP A C   1 
ATOM   1546 O  O   . ASP A 1 200 ? 80.18503  -25.28166 -6.72985  1.000 39.83384  ? 200 ASP A O   1 
ATOM   1547 C  CB  . ASP A 1 200 ? 82.96262  -26.18624 -7.15692  1.000 46.17484  ? 200 ASP A CB  1 
ATOM   1548 C  CG  . ASP A 1 200 ? 84.06778  -26.60761 -8.10227  1.000 51.52277  ? 200 ASP A CG  1 
ATOM   1549 O  OD1 . ASP A 1 200 ? 83.98475  -26.28040 -9.30715  1.000 55.46869  ? 200 ASP A OD1 1 
ATOM   1550 O  OD2 . ASP A 1 200 ? 85.02008  -27.26750 -7.63848  1.000 54.13025  ? 200 ASP A OD2 1 
ATOM   1551 N  N   . SER A 1 201 ? 81.21352  -23.54239 -5.74318  1.000 34.07992  ? 201 SER A N   1 
ATOM   1552 C  CA  . SER A 1 201 ? 80.12056  -23.33825 -4.80272  1.000 39.40142  ? 201 SER A CA  1 
ATOM   1553 C  C   . SER A 1 201 ? 78.83438  -22.96266 -5.53148  1.000 41.30595  ? 201 SER A C   1 
ATOM   1554 O  O   . SER A 1 201 ? 78.84971  -22.41516 -6.63856  1.000 35.32371  ? 201 SER A O   1 
ATOM   1555 C  CB  . SER A 1 201 ? 80.47864  -22.25355 -3.78527  1.000 41.59208  ? 201 SER A CB  1 
ATOM   1556 O  OG  . SER A 1 201 ? 80.46620  -20.96463 -4.37155  1.000 34.57106  ? 201 SER A OG  1 
ATOM   1557 N  N   . ALA A 1 202 ? 77.70726  -23.26694 -4.88856  1.000 37.81318  ? 202 ALA A N   1 
ATOM   1558 C  CA  . ALA A 1 202 ? 76.41168  -22.94468 -5.47182  1.000 37.05225  ? 202 ALA A CA  1 
ATOM   1559 C  C   . ALA A 1 202 ? 76.24336  -21.44043 -5.64614  1.000 39.27927  ? 202 ALA A C   1 
ATOM   1560 O  O   . ALA A 1 202 ? 75.61303  -20.98689 -6.60835  1.000 38.15330  ? 202 ALA A O   1 
ATOM   1561 C  CB  . ALA A 1 202 ? 75.29296  -23.51716 -4.60058  1.000 37.44827  ? 202 ALA A CB  1 
ATOM   1562 N  N   . VAL A 1 203 ? 76.81008  -20.64876 -4.73218  1.000 33.93074  ? 203 VAL A N   1 
ATOM   1563 C  CA  . VAL A 1 203 ? 76.63673  -19.20097 -4.80298  1.000 39.00591  ? 203 VAL A CA  1 
ATOM   1564 C  C   . VAL A 1 203 ? 77.47567  -18.61066 -5.93044  1.000 37.72909  ? 203 VAL A C   1 
ATOM   1565 O  O   . VAL A 1 203 ? 77.01007  -17.74264 -6.67754  1.000 39.43546  ? 203 VAL A O   1 
ATOM   1566 C  CB  . VAL A 1 203 ? 76.96927  -18.55705 -3.44545  1.000 41.61392  ? 203 VAL A CB  1 
ATOM   1567 C  CG1 . VAL A 1 203 ? 77.04604  -17.04068 -3.57469  1.000 38.51215  ? 203 VAL A CG1 1 
ATOM   1568 C  CG2 . VAL A 1 203 ? 75.92810  -18.95619 -2.40870  1.000 39.77422  ? 203 VAL A CG2 1 
ATOM   1569 N  N   . MET A 1 204 ? 78.72204  -19.06655 -6.07517  1.000 38.61309  ? 204 MET A N   1 
ATOM   1570 C  CA  . MET A 1 204 ? 79.55288  -18.57111 -7.16760  1.000 38.11981  ? 204 MET A CA  1 
ATOM   1571 C  C   . MET A 1 204 ? 79.02367  -19.04495 -8.51475  1.000 41.07618  ? 204 MET A C   1 
ATOM   1572 O  O   . MET A 1 204 ? 79.08350  -18.30666 -9.50426  1.000 39.73949  ? 204 MET A O   1 
ATOM   1573 C  CB  . MET A 1 204 ? 81.00647  -19.00432 -6.97948  1.000 38.47572  ? 204 MET A CB  1 
ATOM   1574 C  CG  . MET A 1 204 ? 81.95409  -18.40854 -8.02506  1.000 42.09908  ? 204 MET A CG  1 
ATOM   1575 S  SD  . MET A 1 204 ? 81.82448  -16.60473 -8.14754  1.000 43.13070  ? 204 MET A SD  1 
ATOM   1576 C  CE  . MET A 1 204 ? 82.51575  -16.12508 -6.56621  1.000 38.14456  ? 204 MET A CE  1 
ATOM   1577 N  N   . SER A 1 205 ? 78.50130  -20.27359 -8.56964  1.000 40.12638  ? 205 SER A N   1 
ATOM   1578 C  CA  A SER A 1 205 ? 77.89288  -20.75934 -9.80321  0.563 39.56920  ? 205 SER A CA  1 
ATOM   1579 C  CA  B SER A 1 205 ? 77.88714  -20.76366 -9.79918  0.437 39.40085  ? 205 SER A CA  1 
ATOM   1580 C  C   . SER A 1 205 ? 76.72214  -19.87865 -10.22052 1.000 40.76002  ? 205 SER A C   1 
ATOM   1581 O  O   . SER A 1 205 ? 76.53712  -19.60589 -11.41279 1.000 39.90976  ? 205 SER A O   1 
ATOM   1582 C  CB  A SER A 1 205 ? 77.44062  -22.21049 -9.63512  0.563 37.79062  ? 205 SER A CB  1 
ATOM   1583 C  CB  B SER A 1 205 ? 77.42139  -22.20788 -9.61308  0.437 37.65102  ? 205 SER A CB  1 
ATOM   1584 O  OG  A SER A 1 205 ? 78.54870  -23.07769 -9.47058  0.563 38.64451  ? 205 SER A OG  1 
ATOM   1585 O  OG  B SER A 1 205 ? 76.56189  -22.60920 -10.66665 0.437 40.41892  ? 205 SER A OG  1 
ATOM   1586 N  N   . ALA A 1 206 ? 75.92448  -19.42136 -9.25234  1.000 40.27510  ? 206 ALA A N   1 
ATOM   1587 C  CA  . ALA A 1 206 ? 74.80026  -18.54663 -9.56767  1.000 40.84322  ? 206 ALA A CA  1 
ATOM   1588 C  C   . ALA A 1 206 ? 75.28288  -17.17783 -10.02831 1.000 37.78951  ? 206 ALA A C   1 
ATOM   1589 O  O   . ALA A 1 206 ? 74.68902  -16.57427 -10.92820 1.000 41.60458  ? 206 ALA A O   1 
ATOM   1590 C  CB  . ALA A 1 206 ? 73.88102  -18.41472 -8.35365  1.000 35.21992  ? 206 ALA A CB  1 
ATOM   1591 N  N   . MET A 1 207 ? 76.35750  -16.67059 -9.42234  1.000 34.97709  ? 207 MET A N   1 
ATOM   1592 C  CA  . MET A 1 207 ? 76.91804  -15.40022 -9.86833  1.000 36.97724  ? 207 MET A CA  1 
ATOM   1593 C  C   . MET A 1 207 ? 77.45489  -15.51086 -11.28824 1.000 42.14613  ? 207 MET A C   1 
ATOM   1594 O  O   . MET A 1 207 ? 77.25980  -14.60455 -12.10668 1.000 40.65325  ? 207 MET A O   1 
ATOM   1595 C  CB  . MET A 1 207 ? 78.02138  -14.94361 -8.91062  1.000 34.08422  ? 207 MET A CB  1 
ATOM   1596 C  CG  . MET A 1 207 ? 77.51806  -14.54155 -7.53262  1.000 37.19321  ? 207 MET A CG  1 
ATOM   1597 S  SD  . MET A 1 207 ? 78.85464  -14.21864 -6.36577  1.000 43.38537  ? 207 MET A SD  1 
ATOM   1598 C  CE  . MET A 1 207 ? 79.87680  -13.07986 -7.29848  1.000 41.92005  ? 207 MET A CE  1 
ATOM   1599 N  N   . LEU A 1 208 ? 78.13589  -16.61718 -11.59836 1.000 37.42720  ? 208 LEU A N   1 
ATOM   1600 C  CA  . LEU A 1 208 ? 78.66241  -16.80623 -12.94521 1.000 39.03556  ? 208 LEU A CA  1 
ATOM   1601 C  C   . LEU A 1 208 ? 77.53657  -16.98630 -13.95351 1.000 37.53258  ? 208 LEU A C   1 
ATOM   1602 O  O   . LEU A 1 208 ? 77.63684  -16.51506 -15.09203 1.000 38.31610  ? 208 LEU A O   1 
ATOM   1603 C  CB  . LEU A 1 208 ? 79.61761  -18.00022 -12.97397 1.000 30.53732  ? 208 LEU A CB  1 
ATOM   1604 C  CG  . LEU A 1 208 ? 80.96582  -17.76013 -12.29011 1.000 36.93135  ? 208 LEU A CG  1 
ATOM   1605 C  CD1 . LEU A 1 208 ? 81.71542  -19.06634 -12.07693 1.000 42.02387  ? 208 LEU A CD1 1 
ATOM   1606 C  CD2 . LEU A 1 208 ? 81.81119  -16.78782 -13.10169 1.000 36.77815  ? 208 LEU A CD2 1 
ATOM   1607 N  N   . GLN A 1 209 ? 76.45179  -17.65455 -13.55156 1.000 34.64066  ? 209 GLN A N   1 
ATOM   1608 C  CA  . GLN A 1 209 ? 75.31662  -17.81781 -14.45300 1.000 37.79894  ? 209 GLN A CA  1 
ATOM   1609 C  C   . GLN A 1 209 ? 74.67125  -16.47593 -14.77844 1.000 45.55405  ? 209 GLN A C   1 
ATOM   1610 O  O   . GLN A 1 209 ? 74.23933  -16.24695 -15.91482 1.000 40.79372  ? 209 GLN A O   1 
ATOM   1611 C  CB  . GLN A 1 209 ? 74.28725  -18.77040 -13.84876 1.000 40.46339  ? 209 GLN A CB  1 
ATOM   1612 C  CG  . GLN A 1 209 ? 73.08256  -19.01103 -14.75475 1.000 50.09746  ? 209 GLN A CG  1 
ATOM   1613 C  CD  . GLN A 1 209 ? 71.98181  -19.80662 -14.08076 1.000 62.12729  ? 209 GLN A CD  1 
ATOM   1614 O  OE1 . GLN A 1 209 ? 71.20507  -19.26699 -13.28849 1.000 62.26178  ? 209 GLN A OE1 1 
ATOM   1615 N  NE2 . GLN A 1 209 ? 71.90666  -21.09653 -14.39351 1.000 61.96191  ? 209 GLN A NE2 1 
ATOM   1616 N  N   . ILE A 1 210 ? 74.59489  -15.57567 -13.79462 1.000 37.67739  ? 210 ILE A N   1 
ATOM   1617 C  CA  . ILE A 1 210 ? 74.08469  -14.23274 -14.06068 1.000 43.25536  ? 210 ILE A CA  1 
ATOM   1618 C  C   . ILE A 1 210 ? 74.98298  -13.50989 -15.05550 1.000 37.24014  ? 210 ILE A C   1 
ATOM   1619 O  O   . ILE A 1 210 ? 74.50262  -12.85334 -15.98642 1.000 40.53194  ? 210 ILE A O   1 
ATOM   1620 C  CB  . ILE A 1 210 ? 73.94710  -13.44209 -12.74804 1.000 38.89466  ? 210 ILE A CB  1 
ATOM   1621 C  CG1 . ILE A 1 210 ? 72.79341  -13.99660 -11.91075 1.000 40.49730  ? 210 ILE A CG1 1 
ATOM   1622 C  CG2 . ILE A 1 210 ? 73.76073  -11.96003 -13.03395 1.000 37.26654  ? 210 ILE A CG2 1 
ATOM   1623 C  CD1 . ILE A 1 210 ? 72.70264  -13.39106 -10.52790 1.000 38.74004  ? 210 ILE A CD1 1 
ATOM   1624 N  N   . ALA A 1 211 ? 76.30039  -13.61752 -14.87356 1.000 36.89692  ? 211 ALA A N   1 
ATOM   1625 C  CA  . ALA A 1 211 ? 77.23220  -12.99943 -15.80984 1.000 38.80498  ? 211 ALA A CA  1 
ATOM   1626 C  C   . ALA A 1 211 ? 77.05016  -13.55748 -17.21523 1.000 42.95232  ? 211 ALA A C   1 
ATOM   1627 O  O   . ALA A 1 211 ? 77.09237  -12.80824 -18.19827 1.000 42.40561  ? 211 ALA A O   1 
ATOM   1628 C  CB  . ALA A 1 211 ? 78.66927  -13.20727 -15.33384 1.000 36.25106  ? 211 ALA A CB  1 
ATOM   1629 N  N   . VAL A 1 212 ? 76.84085  -14.87253 -17.32736 1.000 39.37295  ? 212 VAL A N   1 
ATOM   1630 C  CA  . VAL A 1 212 ? 76.59553  -15.48559 -18.63051 1.000 39.24840  ? 212 VAL A CA  1 
ATOM   1631 C  C   . VAL A 1 212 ? 75.28864  -14.96997 -19.21813 1.000 41.36219  ? 212 VAL A C   1 
ATOM   1632 O  O   . VAL A 1 212 ? 75.23715  -14.52893 -20.37236 1.000 45.57581  ? 212 VAL A O   1 
ATOM   1633 C  CB  . VAL A 1 212 ? 76.58977  -17.02228 -18.51450 1.000 44.07102  ? 212 VAL A CB  1 
ATOM   1634 C  CG1 . VAL A 1 212 ? 76.18434  -17.65150 -19.83631 1.000 43.04887  ? 212 VAL A CG1 1 
ATOM   1635 C  CG2 . VAL A 1 212 ? 77.95536  -17.54027 -18.07885 1.000 35.51847  ? 212 VAL A CG2 1 
ATOM   1636 N  N   . ASP A 1 213 ? 74.21427  -15.00721 -18.42461 1.000 40.77363  ? 213 ASP A N   1 
ATOM   1637 C  CA  . ASP A 1 213 ? 72.89623  -14.64039 -18.93443 1.000 44.60562  ? 213 ASP A CA  1 
ATOM   1638 C  C   . ASP A 1 213 ? 72.83827  -13.17229 -19.34016 1.000 49.37288  ? 213 ASP A C   1 
ATOM   1639 O  O   . ASP A 1 213 ? 72.22780  -12.82778 -20.35904 1.000 45.52383  ? 213 ASP A O   1 
ATOM   1640 C  CB  . ASP A 1 213 ? 71.82493  -14.95044 -17.88805 1.000 46.09905  ? 213 ASP A CB  1 
ATOM   1641 C  CG  . ASP A 1 213 ? 71.57974  -16.43841 -17.72751 1.000 52.21453  ? 213 ASP A CG  1 
ATOM   1642 O  OD1 . ASP A 1 213 ? 72.19857  -17.22918 -18.47178 1.000 52.20057  ? 213 ASP A OD1 1 
ATOM   1643 O  OD2 . ASP A 1 213 ? 70.76857  -16.81912 -16.85729 1.000 60.45250  ? 213 ASP A OD2 1 
ATOM   1644 N  N   . VAL A 1 214 ? 73.46381  -12.29184 -18.55675 1.000 42.68387  ? 214 VAL A N   1 
ATOM   1645 C  CA  . VAL A 1 214 ? 73.43366  -10.86756 -18.87654 1.000 44.38894  ? 214 VAL A CA  1 
ATOM   1646 C  C   . VAL A 1 214 ? 74.18885  -10.59323 -20.16916 1.000 43.26097  ? 214 VAL A C   1 
ATOM   1647 O  O   . VAL A 1 214 ? 73.76566  -9.76838  -20.98703 1.000 44.10845  ? 214 VAL A O   1 
ATOM   1648 C  CB  . VAL A 1 214 ? 73.99294  -10.04597 -17.69992 1.000 44.37774  ? 214 VAL A CB  1 
ATOM   1649 C  CG1 . VAL A 1 214 ? 74.26267  -8.60515  -18.11728 1.000 44.25429  ? 214 VAL A CG1 1 
ATOM   1650 C  CG2 . VAL A 1 214 ? 73.01664  -10.07721 -16.54412 1.000 41.25918  ? 214 VAL A CG2 1 
ATOM   1651 N  N   . ASN A 1 215 ? 75.30562  -11.29176 -20.38448 1.000 46.02118  ? 215 ASN A N   1 
ATOM   1652 C  CA  . ASN A 1 215 ? 76.09643  -11.06961 -21.59057 1.000 44.61313  ? 215 ASN A CA  1 
ATOM   1653 C  C   . ASN A 1 215 ? 75.33063  -11.47526 -22.84322 1.000 48.89167  ? 215 ASN A C   1 
ATOM   1654 O  O   . ASN A 1 215 ? 75.40051  -10.78995 -23.87033 1.000 45.34270  ? 215 ASN A O   1 
ATOM   1655 C  CB  . ASN A 1 215 ? 77.41118  -11.84088 -21.50506 1.000 43.13800  ? 215 ASN A CB  1 
ATOM   1656 C  CG  . ASN A 1 215 ? 78.57089  -10.97899 -21.05168 1.000 47.10762  ? 215 ASN A CG  1 
ATOM   1657 O  OD1 . ASN A 1 215 ? 79.35246  -10.49856 -21.86889 1.000 46.99551  ? 215 ASN A OD1 1 
ATOM   1658 N  ND2 . ASN A 1 215 ? 78.69952  -10.79374 -19.74404 1.000 37.63989  ? 215 ASN A ND2 1 
ATOM   1659 N  N   . LEU A 1 216 ? 74.60160  -12.59200 -22.78567 1.000 44.74389  ? 216 LEU A N   1 
ATOM   1660 C  CA  . LEU A 1 216 ? 73.89507  -13.05374 -23.97484 1.000 51.98593  ? 216 LEU A CA  1 
ATOM   1661 C  C   . LEU A 1 216 ? 72.62438  -12.25119 -24.22813 1.000 49.94036  ? 216 LEU A C   1 
ATOM   1662 O  O   . LEU A 1 216 ? 72.23179  -12.07751 -25.38668 1.000 49.18907  ? 216 LEU A O   1 
ATOM   1663 C  CB  . LEU A 1 216 ? 73.58856  -14.55220 -23.86469 1.000 53.79303  ? 216 LEU A CB  1 
ATOM   1664 C  CG  . LEU A 1 216 ? 72.41674  -15.07578 -23.03134 1.000 57.07216  ? 216 LEU A CG  1 
ATOM   1665 C  CD1 . LEU A 1 216 ? 71.17967  -15.29018 -23.89908 1.000 52.51537  ? 216 LEU A CD1 1 
ATOM   1666 C  CD2 . LEU A 1 216 ? 72.81149  -16.36579 -22.32221 1.000 55.98913  ? 216 LEU A CD2 1 
ATOM   1667 N  N   . LEU A 1 217 ? 71.97365  -11.75402 -23.17237 1.000 44.55292  ? 217 LEU A N   1 
ATOM   1668 C  CA  . LEU A 1 217 ? 70.84861  -10.84388 -23.36515 1.000 45.62919  ? 217 LEU A CA  1 
ATOM   1669 C  C   . LEU A 1 217 ? 71.31113  -9.52813  -23.97979 1.000 49.27262  ? 217 LEU A C   1 
ATOM   1670 O  O   . LEU A 1 217 ? 70.66900  -9.00079  -24.89561 1.000 47.31022  ? 217 LEU A O   1 
ATOM   1671 C  CB  . LEU A 1 217 ? 70.13684  -10.59314 -22.03494 1.000 44.73477  ? 217 LEU A CB  1 
ATOM   1672 C  CG  . LEU A 1 217 ? 69.40630  -11.78497 -21.41328 1.000 54.02283  ? 217 LEU A CG  1 
ATOM   1673 C  CD1 . LEU A 1 217 ? 68.92823  -11.45018 -20.00226 1.000 51.28436  ? 217 LEU A CD1 1 
ATOM   1674 C  CD2 . LEU A 1 217 ? 68.24361  -12.22371 -22.29658 1.000 54.72390  ? 217 LEU A CD2 1 
ATOM   1675 N  N   . LEU A 1 218 ? 72.42357  -8.98123  -23.48189 1.000 46.06185  ? 218 LEU A N   1 
ATOM   1676 C  CA  . LEU A 1 218 ? 72.99084  -7.77096  -24.06844 1.000 49.62087  ? 218 LEU A CA  1 
ATOM   1677 C  C   . LEU A 1 218 ? 73.36236  -7.98970  -25.52880 1.000 54.29889  ? 218 LEU A C   1 
ATOM   1678 O  O   . LEU A 1 218 ? 73.12275  -7.12241  -26.37724 1.000 54.37770  ? 218 LEU A O   1 
ATOM   1679 C  CB  . LEU A 1 218 ? 74.22056  -7.33069  -23.27203 1.000 46.71391  ? 218 LEU A CB  1 
ATOM   1680 C  CG  . LEU A 1 218 ? 74.07089  -6.24694  -22.20127 1.000 57.55047  ? 218 LEU A CG  1 
ATOM   1681 C  CD1 . LEU A 1 218 ? 72.75831  -6.37706  -21.44611 1.000 58.24432  ? 218 LEU A CD1 1 
ATOM   1682 C  CD2 . LEU A 1 218 ? 75.24546  -6.30610  -21.23438 1.000 54.00774  ? 218 LEU A CD2 1 
ATOM   1683 N  N   . ASN A 1 219 ? 73.95033  -9.14677  -25.83924 1.000 48.83899  ? 219 ASN A N   1 
ATOM   1684 C  CA  . ASN A 1 219 ? 74.39886  -9.40897  -27.20090 1.000 49.92215  ? 219 ASN A CA  1 
ATOM   1685 C  C   . ASN A 1 219 ? 73.22038  -9.60049  -28.14679 1.000 53.51821  ? 219 ASN A C   1 
ATOM   1686 O  O   . ASN A 1 219 ? 73.26490  -9.15017  -29.29736 1.000 52.85210  ? 219 ASN A O   1 
ATOM   1687 C  CB  . ASN A 1 219 ? 75.31351  -10.63293 -27.22389 1.000 49.17449  ? 219 ASN A CB  1 
ATOM   1688 C  CG  . ASN A 1 219 ? 75.80304  -10.96738 -28.61837 1.000 54.35411  ? 219 ASN A CG  1 
ATOM   1689 O  OD1 . ASN A 1 219 ? 75.20462  -11.78150 -29.31865 1.000 55.47478  ? 219 ASN A OD1 1 
ATOM   1690 N  ND2 . ASN A 1 219 ? 76.89616  -10.33635 -29.02971 1.000 56.23025  ? 219 ASN A ND2 1 
ATOM   1691 N  N   . ASP A 1 220 ? 72.15668  -10.26271 -27.68277 1.000 48.03851  ? 220 ASP A N   1 
ATOM   1692 C  CA  . ASP A 1 220 ? 71.00730  -10.50266 -28.54977 1.000 49.59359  ? 220 ASP A CA  1 
ATOM   1693 C  C   . ASP A 1 220 ? 70.28175  -9.21144  -28.90387 1.000 58.74119  ? 220 ASP A C   1 
ATOM   1694 O  O   . ASP A 1 220 ? 69.63678  -9.13521  -29.95618 1.000 57.04678  ? 220 ASP A O   1 
ATOM   1695 C  CB  . ASP A 1 220 ? 70.04164  -11.49091 -27.89685 1.000 47.38653  ? 220 ASP A CB  1 
ATOM   1696 C  CG  . ASP A 1 220 ? 70.40312  -12.93454 -28.18829 1.000 51.04392  ? 220 ASP A CG  1 
ATOM   1697 O  OD1 . ASP A 1 220 ? 71.49268  -13.17250 -28.74939 1.000 54.22413  ? 220 ASP A OD1 1 
ATOM   1698 O  OD2 . ASP A 1 220 ? 69.59593  -13.83019 -27.86611 1.000 57.76732  ? 220 ASP A OD2 1 
ATOM   1699 N  N   . ILE A 1 221 ? 70.37158  -8.19162  -28.05269 1.000 53.06227  ? 221 ILE A N   1 
ATOM   1700 C  CA  . ILE A 1 221 ? 69.77660  -6.90319  -28.38884 1.000 56.71315  ? 221 ILE A CA  1 
ATOM   1701 C  C   . ILE A 1 221 ? 70.70001  -6.10474  -29.29967 1.000 54.32746  ? 221 ILE A C   1 
ATOM   1702 O  O   . ILE A 1 221 ? 70.26129  -5.53577  -30.30506 1.000 55.29093  ? 221 ILE A O   1 
ATOM   1703 C  CB  . ILE A 1 221 ? 69.42926  -6.11885  -27.11178 1.000 56.55699  ? 221 ILE A CB  1 
ATOM   1704 C  CG1 . ILE A 1 221 ? 68.23851  -6.76435  -26.40102 1.000 55.56398  ? 221 ILE A CG1 1 
ATOM   1705 C  CG2 . ILE A 1 221 ? 69.13733  -4.66932  -27.45106 1.000 48.42650  ? 221 ILE A CG2 1 
ATOM   1706 C  CD1 . ILE A 1 221 ? 67.69745  -5.94933  -25.25429 1.000 59.91342  ? 221 ILE A CD1 1 
ATOM   1707 N  N   . ALA A 1 222 ? 71.99277  -6.05406  -28.96679 1.000 52.01289  ? 222 ALA A N   1 
ATOM   1708 C  CA  . ALA A 1 222 ? 72.93820  -5.29822  -29.78396 1.000 51.60335  ? 222 ALA A CA  1 
ATOM   1709 C  C   . ALA A 1 222 ? 73.02438  -5.84026  -31.20576 1.000 55.47877  ? 222 ALA A C   1 
ATOM   1710 O  O   . ALA A 1 222 ? 73.22657  -5.06940  -32.15102 1.000 55.85441  ? 222 ALA A O   1 
ATOM   1711 C  CB  . ALA A 1 222 ? 74.32193  -5.30682  -29.13409 1.000 48.41623  ? 222 ALA A CB  1 
ATOM   1712 N  N   . SER A 1 223 ? 72.88495  -7.15468  -31.37914 1.000 56.40595  ? 223 SER A N   1 
ATOM   1713 C  CA  . SER A 1 223 ? 72.94587  -7.78510  -32.69030 1.000 58.95369  ? 223 SER A CA  1 
ATOM   1714 C  C   . SER A 1 223 ? 71.56306  -8.12695  -33.23523 1.000 62.61383  ? 223 SER A C   1 
ATOM   1715 O  O   . SER A 1 223 ? 71.44688  -8.97259  -34.12896 1.000 61.49615  ? 223 SER A O   1 
ATOM   1716 C  CB  . SER A 1 223 ? 73.81431  -9.04344  -32.63355 1.000 58.38758  ? 223 SER A CB  1 
ATOM   1717 O  OG  . SER A 1 223 ? 73.16365  -10.07777 -31.91647 1.000 60.32957  ? 223 SER A OG  1 
ATOM   1718 N  N   . LEU A 1 224 ? 70.51357  -7.48449  -32.71744 1.000 57.66916  ? 224 LEU A N   1 
ATOM   1719 C  CA  . LEU A 1 224 ? 69.15993  -7.80883  -33.15594 1.000 64.25378  ? 224 LEU A CA  1 
ATOM   1720 C  C   . LEU A 1 224 ? 68.94615  -7.44168  -34.62031 1.000 69.45614  ? 224 LEU A C   1 
ATOM   1721 O  O   . LEU A 1 224 ? 68.35504  -8.21688  -35.38101 1.000 66.57850  ? 224 LEU A O   1 
ATOM   1722 C  CB  . LEU A 1 224 ? 68.13874  -7.09780  -32.26775 1.000 57.71369  ? 224 LEU A CB  1 
ATOM   1723 C  CG  . LEU A 1 224 ? 66.66200  -7.31444  -32.60437 1.000 66.55098  ? 224 LEU A CG  1 
ATOM   1724 C  CD1 . LEU A 1 224 ? 66.30754  -8.79305  -32.54233 1.000 65.91203  ? 224 LEU A CD1 1 
ATOM   1725 C  CD2 . LEU A 1 224 ? 65.77661  -6.50132  -31.66781 1.000 65.11901  ? 224 LEU A CD2 1 
ATOM   1726 N  N   . GLU A 1 225 ? 69.43065  -6.26829  -35.03547 1.000 65.49880  ? 225 GLU A N   1 
ATOM   1727 C  CA  . GLU A 1 225 ? 69.20704  -5.80827  -36.40360 1.000 70.03119  ? 225 GLU A CA  1 
ATOM   1728 C  C   . GLU A 1 225 ? 69.88535  -6.72553  -37.41490 1.000 69.03376  ? 225 GLU A C   1 
ATOM   1729 O  O   . GLU A 1 225 ? 69.26788  -7.14339  -38.40113 1.000 68.73585  ? 225 GLU A O   1 
ATOM   1730 C  CB  . GLU A 1 225 ? 69.70502  -4.37070  -36.55943 1.000 67.44291  ? 225 GLU A CB  1 
ATOM   1731 N  N   . LYS A 1 226 ? 71.16100  -7.04956  -37.18317 1.000 69.73730  ? 226 LYS A N   1 
ATOM   1732 C  CA  . LYS A 1 226 ? 71.89087  -7.92119  -38.10007 1.000 66.74927  ? 226 LYS A CA  1 
ATOM   1733 C  C   . LYS A 1 226 ? 71.17849  -9.25284  -38.28729 1.000 72.27778  ? 226 LYS A C   1 
ATOM   1734 O  O   . LYS A 1 226 ? 71.03528  -9.73748  -39.41552 1.000 72.70593  ? 226 LYS A O   1 
ATOM   1735 C  CB  . LYS A 1 226 ? 73.30708  -8.16408  -37.58041 1.000 69.68663  ? 226 LYS A CB  1 
ATOM   1736 C  CG  . LYS A 1 226 ? 74.08009  -6.91210  -37.21617 1.000 74.02343  ? 226 LYS A CG  1 
ATOM   1737 C  CD  . LYS A 1 226 ? 75.23911  -7.25359  -36.28878 1.000 74.65652  ? 226 LYS A CD  1 
ATOM   1738 C  CE  . LYS A 1 226 ? 76.09965  -8.37381  -36.85984 1.000 72.47759  ? 226 LYS A CE  1 
ATOM   1739 N  NZ  . LYS A 1 226 ? 77.19492  -8.76750  -35.92848 1.000 70.16132  ? 226 LYS A NZ  1 
ATOM   1740 N  N   . GLU A 1 227 ? 70.72066  -9.85699  -37.19134 1.000 71.51664  ? 227 GLU A N   1 
ATOM   1741 C  CA  . GLU A 1 227 ? 70.17504  -11.20549 -37.24790 1.000 72.42385  ? 227 GLU A CA  1 
ATOM   1742 C  C   . GLU A 1 227 ? 68.74986  -11.24718 -37.78465 1.000 75.66566  ? 227 GLU A C   1 
ATOM   1743 O  O   . GLU A 1 227 ? 68.31337  -12.30337 -38.25563 1.000 73.81855  ? 227 GLU A O   1 
ATOM   1744 C  CB  . GLU A 1 227 ? 70.25774  -11.84723 -35.86207 1.000 67.61227  ? 227 GLU A CB  1 
ATOM   1745 C  CG  . GLU A 1 227 ? 71.69214  -11.93264 -35.35221 1.000 67.66137  ? 227 GLU A CG  1 
ATOM   1746 C  CD  . GLU A 1 227 ? 71.82308  -12.69421 -34.05001 1.000 70.96678  ? 227 GLU A CD  1 
ATOM   1747 O  OE1 . GLU A 1 227 ? 70.78555  -13.00821 -33.42921 1.000 73.88189  ? 227 GLU A OE1 1 
ATOM   1748 O  OE2 . GLU A 1 227 ? 72.97039  -12.98118 -33.64875 1.000 67.11234  ? 227 GLU A OE2 1 
ATOM   1749 N  N   . GLU A 1 228 ? 68.01716  -10.13227 -37.73232 1.000 71.95255  ? 228 GLU A N   1 
ATOM   1750 C  CA  . GLU A 1 228 ? 66.76686  -10.05000 -38.48052 1.000 78.27433  ? 228 GLU A CA  1 
ATOM   1751 C  C   . GLU A 1 228 ? 67.03871  -10.04945 -39.97956 1.000 76.44906  ? 228 GLU A C   1 
ATOM   1752 O  O   . GLU A 1 228 ? 66.36128  -10.74446 -40.74601 1.000 70.97776  ? 228 GLU A O   1 
ATOM   1753 C  CB  . GLU A 1 228 ? 65.98128  -8.79845  -38.08409 1.000 75.65556  ? 228 GLU A CB  1 
ATOM   1754 C  CG  . GLU A 1 228 ? 65.50667  -8.76614  -36.64406 1.000 84.01484  ? 228 GLU A CG  1 
ATOM   1755 C  CD  . GLU A 1 228 ? 64.53177  -7.63220  -36.38210 1.000 91.32122  ? 228 GLU A CD  1 
ATOM   1756 O  OE1 . GLU A 1 228 ? 63.57759  -7.47082  -37.17399 1.000 100.75269 ? 228 GLU A OE1 1 
ATOM   1757 O  OE2 . GLU A 1 228 ? 64.72101  -6.89886  -35.38872 1.000 85.19789  ? 228 GLU A OE2 1 
ATOM   1758 N  N   . ALA A 1 229 ? 68.04217  -9.28000  -40.41223 1.000 76.72206  ? 229 ALA A N   1 
ATOM   1759 C  CA  . ALA A 1 229 ? 68.35979  -9.17167  -41.83118 1.000 73.02541  ? 229 ALA A CA  1 
ATOM   1760 C  C   . ALA A 1 229 ? 68.84720  -10.48702 -42.42268 1.000 78.33473  ? 229 ALA A C   1 
ATOM   1761 O  O   . ALA A 1 229 ? 68.90475  -10.61606 -43.65016 1.000 82.13648  ? 229 ALA A O   1 
ATOM   1762 C  CB  . ALA A 1 229 ? 69.41002  -8.08158  -42.04991 1.000 65.39024  ? 229 ALA A CB  1 
ATOM   1763 N  N   . ARG A 1 230 ? 69.19620  -11.46338 -41.58562 1.000 75.20745  ? 230 ARG A N   1 
ATOM   1764 C  CA  . ARG A 1 230 ? 69.62538  -12.77701 -42.04714 1.000 77.09799  ? 230 ARG A CA  1 
ATOM   1765 C  C   . ARG A 1 230 ? 68.60619  -13.86562 -41.73378 1.000 74.69670  ? 230 ARG A C   1 
ATOM   1766 O  O   . ARG A 1 230 ? 68.88500  -15.04738 -41.96414 1.000 73.61451  ? 230 ARG A O   1 
ATOM   1767 C  CB  . ARG A 1 230 ? 70.98112  -13.13741 -41.43523 1.000 77.34247  ? 230 ARG A CB  1 
ATOM   1768 C  CG  . ARG A 1 230 ? 71.99043  -12.00545 -41.47241 1.000 82.16596  ? 230 ARG A CG  1 
ATOM   1769 C  CD  . ARG A 1 230 ? 73.36643  -12.47363 -41.02970 1.000 89.46831  ? 230 ARG A CD  1 
ATOM   1770 N  NE  . ARG A 1 230 ? 73.98779  -13.34110 -42.02323 1.000 94.14663  ? 230 ARG A NE  1 
ATOM   1771 C  CZ  . ARG A 1 230 ? 75.22770  -13.80398 -41.94212 1.000 90.97409  ? 230 ARG A CZ  1 
ATOM   1772 N  NH1 . ARG A 1 230 ? 76.00844  -13.51278 -40.91477 1.000 88.23687  ? 230 ARG A NH1 1 
ATOM   1773 N  NH2 . ARG A 1 230 ? 75.69763  -14.57573 -42.91791 1.000 81.09791  ? 230 ARG A NH2 1 
ATOM   1774 N  N   . GLY A 1 231 ? 67.43822  -13.49992 -41.21449 1.000 71.40715  ? 231 GLY A N   1 
ATOM   1775 C  CA  . GLY A 1 231 ? 66.42637  -14.49274 -40.88420 1.000 76.81224  ? 231 GLY A CA  1 
ATOM   1776 C  C   . GLY A 1 231 ? 66.84424  -15.45600 -39.79468 1.000 82.93414  ? 231 GLY A C   1 
ATOM   1777 O  O   . GLY A 1 231 ? 66.52781  -16.65046 -39.86889 1.000 80.76070  ? 231 GLY A O   1 
ATOM   1778 N  N   . GLU A 1 232 ? 67.55609  -14.96499 -38.78318 1.000 81.75775  ? 232 GLU A N   1 
ATOM   1779 C  CA  . GLU A 1 232 ? 67.97708  -15.80688 -37.67310 1.000 77.59086  ? 232 GLU A CA  1 
ATOM   1780 C  C   . GLU A 1 232 ? 66.82571  -16.00953 -36.69738 1.000 78.46876  ? 232 GLU A C   1 
ATOM   1781 O  O   . GLU A 1 232 ? 66.09546  -15.07001 -36.36883 1.000 83.12592  ? 232 GLU A O   1 
ATOM   1782 C  CB  . GLU A 1 232 ? 69.17479  -15.18590 -36.95343 1.000 79.37822  ? 232 GLU A CB  1 
ATOM   1783 C  CG  . GLU A 1 232 ? 69.56349  -15.89368 -35.66291 1.000 77.07394  ? 232 GLU A CG  1 
ATOM   1784 C  CD  . GLU A 1 232 ? 70.01976  -17.32125 -35.89277 1.000 78.55033  ? 232 GLU A CD  1 
ATOM   1785 O  OE1 . GLU A 1 232 ? 70.89393  -17.53674 -36.75833 1.000 83.14286  ? 232 GLU A OE1 1 
ATOM   1786 O  OE2 . GLU A 1 232 ? 69.50063  -18.22987 -35.21134 1.000 75.46219  ? 232 GLU A OE2 1 
ATOM   1787 N  N   . GLN A 1 233 ? 66.66586  -17.25017 -36.23454 1.000 77.89418  ? 233 GLN A N   1 
ATOM   1788 C  CA  . GLN A 1 233 ? 65.58404  -17.59984 -35.32782 1.000 81.44327  ? 233 GLN A CA  1 
ATOM   1789 C  C   . GLN A 1 233 ? 66.04030  -17.85771 -33.89981 1.000 73.70023  ? 233 GLN A C   1 
ATOM   1790 O  O   . GLN A 1 233 ? 65.22280  -17.74609 -32.98128 1.000 71.21301  ? 233 GLN A O   1 
ATOM   1791 C  CB  . GLN A 1 233 ? 64.83870  -18.83673 -35.85008 1.000 83.31730  ? 233 GLN A CB  1 
ATOM   1792 C  CG  . GLN A 1 233 ? 64.34826  -18.68288 -37.28100 1.000 76.68828  ? 233 GLN A CG  1 
ATOM   1793 C  CD  . GLN A 1 233 ? 63.72615  -19.94972 -37.82914 1.000 89.55165  ? 233 GLN A CD  1 
ATOM   1794 O  OE1 . GLN A 1 233 ? 63.14296  -20.74090 -37.08783 1.000 86.80429  ? 233 GLN A OE1 1 
ATOM   1795 N  NE2 . GLN A 1 233 ? 63.85158  -20.15157 -39.13707 1.000 96.32138  ? 233 GLN A NE2 1 
ATOM   1796 N  N   . ASN A 1 234 ? 67.31272  -18.19337 -33.68842 1.000 67.61951  ? 234 ASN A N   1 
ATOM   1797 C  CA  . ASN A 1 234 ? 67.84083  -18.40546 -32.34004 1.000 70.48122  ? 234 ASN A CA  1 
ATOM   1798 C  C   . ASN A 1 234 ? 68.40512  -17.08707 -31.80656 1.000 67.37046  ? 234 ASN A C   1 
ATOM   1799 O  O   . ASN A 1 234 ? 69.61193  -16.88004 -31.66554 1.000 61.48112  ? 234 ASN A O   1 
ATOM   1800 C  CB  . ASN A 1 234 ? 68.87734  -19.52197 -32.34043 1.000 64.96751  ? 234 ASN A CB  1 
ATOM   1801 C  CG  . ASN A 1 234 ? 68.25133  -20.89442 -32.52789 1.000 66.79873  ? 234 ASN A CG  1 
ATOM   1802 O  OD1 . ASN A 1 234 ? 67.03096  -21.02122 -32.64500 1.000 68.40425  ? 234 ASN A OD1 1 
ATOM   1803 N  ND2 . ASN A 1 234 ? 69.08532  -21.92806 -32.56537 1.000 64.80213  ? 234 ASN A ND2 1 
ATOM   1804 N  N   . ASN A 1 235 ? 67.47753  -16.17546 -31.53161 1.000 61.91353  ? 235 ASN A N   1 
ATOM   1805 C  CA  . ASN A 1 235 ? 67.74739  -14.90833 -30.87236 1.000 61.64144  ? 235 ASN A CA  1 
ATOM   1806 C  C   . ASN A 1 235 ? 66.66825  -14.72149 -29.81907 1.000 66.67551  ? 235 ASN A C   1 
ATOM   1807 O  O   . ASN A 1 235 ? 65.49335  -14.99152 -30.08398 1.000 67.67899  ? 235 ASN A O   1 
ATOM   1808 C  CB  . ASN A 1 235 ? 67.74581  -13.74045 -31.87043 1.000 63.54429  ? 235 ASN A CB  1 
ATOM   1809 C  CG  . ASN A 1 235 ? 68.08718  -12.40815 -31.22277 1.000 61.56308  ? 235 ASN A CG  1 
ATOM   1810 O  OD1 . ASN A 1 235 ? 67.32030  -11.87899 -30.41922 1.000 61.31311  ? 235 ASN A OD1 1 
ATOM   1811 N  ND2 . ASN A 1 235 ? 69.23569  -11.84939 -31.58941 1.000 58.71036  ? 235 ASN A ND2 1 
ATOM   1812 N  N   . MET A 1 236 ? 67.06961  -14.27272 -28.62432 1.000 65.98612  ? 236 MET A N   1 
ATOM   1813 C  CA  . MET A 1 236 ? 66.14243  -14.24584 -27.49377 1.000 63.10567  ? 236 MET A CA  1 
ATOM   1814 C  C   . MET A 1 236 ? 64.89723  -13.42466 -27.80648 1.000 64.78010  ? 236 MET A C   1 
ATOM   1815 O  O   . MET A 1 236 ? 63.79233  -13.77995 -27.38129 1.000 65.49989  ? 236 MET A O   1 
ATOM   1816 C  CB  . MET A 1 236 ? 66.83992  -13.70629 -26.24390 1.000 64.29505  ? 236 MET A CB  1 
ATOM   1817 C  CG  . MET A 1 236 ? 65.94206  -13.65161 -25.01273 1.000 56.58975  ? 236 MET A CG  1 
ATOM   1818 S  SD  . MET A 1 236 ? 65.24035  -15.25663 -24.56464 1.000 67.45561  ? 236 MET A SD  1 
ATOM   1819 C  CE  . MET A 1 236 ? 66.68017  -16.10081 -23.92114 1.000 65.53161  ? 236 MET A CE  1 
ATOM   1820 N  N   . VAL A 1 237 ? 65.05144  -12.32820 -28.55316 1.000 61.01214  ? 237 VAL A N   1 
ATOM   1821 C  CA  . VAL A 1 237 ? 63.89022  -11.53685 -28.95650 1.000 65.44961  ? 237 VAL A CA  1 
ATOM   1822 C  C   . VAL A 1 237 ? 62.94231  -12.38009 -29.80172 1.000 70.32759  ? 237 VAL A C   1 
ATOM   1823 O  O   . VAL A 1 237 ? 61.73128  -12.42290 -29.55412 1.000 73.06400  ? 237 VAL A O   1 
ATOM   1824 C  CB  . VAL A 1 237 ? 64.33482  -10.26919 -29.70774 1.000 67.24945  ? 237 VAL A CB  1 
ATOM   1825 C  CG1 . VAL A 1 237 ? 63.12364  -9.46324  -30.14316 1.000 66.73633  ? 237 VAL A CG1 1 
ATOM   1826 C  CG2 . VAL A 1 237 ? 65.25185  -9.42855  -28.83854 1.000 60.28081  ? 237 VAL A CG2 1 
ATOM   1827 N  N   . MET A 1 238 ? 63.48213  -13.06567 -30.81398 1.000 69.53744  ? 238 MET A N   1 
ATOM   1828 C  CA  . MET A 1 238 ? 62.65007  -13.91573 -31.66149 1.000 71.78963  ? 238 MET A CA  1 
ATOM   1829 C  C   . MET A 1 238 ? 62.03945  -15.06411 -30.86841 1.000 73.93241  ? 238 MET A C   1 
ATOM   1830 O  O   . MET A 1 238 ? 60.86910  -15.41115 -31.06388 1.000 76.31763  ? 238 MET A O   1 
ATOM   1831 C  CB  . MET A 1 238 ? 63.46854  -14.46542 -32.83094 1.000 70.84037  ? 238 MET A CB  1 
ATOM   1832 C  CG  . MET A 1 238 ? 63.74990  -13.47442 -33.94850 1.000 69.69397  ? 238 MET A CG  1 
ATOM   1833 S  SD  . MET A 1 238 ? 64.99912  -12.24660 -33.53293 1.000 83.19285  ? 238 MET A SD  1 
ATOM   1834 C  CE  . MET A 1 238 ? 65.79466  -12.03472 -35.12245 1.000 76.56819  ? 238 MET A CE  1 
ATOM   1835 N  N   . ILE A 1 239 ? 62.81844  -15.66772 -29.96906 1.000 68.86122  ? 239 ILE A N   1 
ATOM   1836 C  CA  . ILE A 1 239 ? 62.34575  -16.84334 -29.24674 1.000 71.44373  ? 239 ILE A CA  1 
ATOM   1837 C  C   . ILE A 1 239 ? 61.23889  -16.47664 -28.26497 1.000 76.72161  ? 239 ILE A C   1 
ATOM   1838 O  O   . ILE A 1 239 ? 60.30948  -17.26430 -28.04515 1.000 75.77187  ? 239 ILE A O   1 
ATOM   1839 C  CB  . ILE A 1 239 ? 63.53456  -17.53339 -28.55371 1.000 71.03830  ? 239 ILE A CB  1 
ATOM   1840 C  CG1 . ILE A 1 239 ? 64.52996  -18.02508 -29.60653 1.000 69.82037  ? 239 ILE A CG1 1 
ATOM   1841 C  CG2 . ILE A 1 239 ? 63.06446  -18.68691 -27.67994 1.000 71.75829  ? 239 ILE A CG2 1 
ATOM   1842 C  CD1 . ILE A 1 239 ? 65.84558  -18.48734 -29.04019 1.000 66.15920  ? 239 ILE A CD1 1 
ATOM   1843 N  N   . LEU A 1 240 ? 61.30384  -15.28305 -27.66885 1.000 75.92556  ? 240 LEU A N   1 
ATOM   1844 C  CA  . LEU A 1 240 ? 60.22753  -14.84804 -26.78415 1.000 81.31634  ? 240 LEU A CA  1 
ATOM   1845 C  C   . LEU A 1 240 ? 58.93411  -14.60902 -27.55152 1.000 86.84491  ? 240 LEU A C   1 
ATOM   1846 O  O   . LEU A 1 240 ? 57.84506  -14.84978 -27.01797 1.000 88.97683  ? 240 LEU A O   1 
ATOM   1847 C  CB  . LEU A 1 240 ? 60.63852  -13.58387 -26.03010 1.000 76.30672  ? 240 LEU A CB  1 
ATOM   1848 C  CG  . LEU A 1 240 ? 61.71500  -13.76100 -24.95848 1.000 73.96478  ? 240 LEU A CG  1 
ATOM   1849 C  CD1 . LEU A 1 240 ? 62.07497  -12.42011 -24.33453 1.000 71.54249  ? 240 LEU A CD1 1 
ATOM   1850 C  CD2 . LEU A 1 240 ? 61.26019  -14.75698 -23.89844 1.000 69.35403  ? 240 LEU A CD2 1 
ATOM   1851 N  N   . ARG A 1 241 ? 59.03033  -14.14265 -28.79917 1.000 89.74944  ? 241 ARG A N   1 
ATOM   1852 C  CA  . ARG A 1 241 ? 57.83054  -13.94719 -29.60575 1.000 87.13354  ? 241 ARG A CA  1 
ATOM   1853 C  C   . ARG A 1 241 ? 57.17810  -15.27124 -29.97906 1.000 85.90414  ? 241 ARG A C   1 
ATOM   1854 O  O   . ARG A 1 241 ? 55.96291  -15.31854 -30.19753 1.000 93.06384  ? 241 ARG A O   1 
ATOM   1855 C  CB  . ARG A 1 241 ? 58.16280  -13.15212 -30.86727 1.000 81.95290  ? 241 ARG A CB  1 
ATOM   1856 C  CG  . ARG A 1 241 ? 58.68833  -11.75380 -30.60757 1.000 84.95290  ? 241 ARG A CG  1 
ATOM   1857 C  CD  . ARG A 1 241 ? 58.59758  -10.90825 -31.86442 1.000 89.30718  ? 241 ARG A CD  1 
ATOM   1858 N  NE  . ARG A 1 241 ? 57.25138  -10.93723 -32.42389 1.000 97.94084  ? 241 ARG A NE  1 
ATOM   1859 C  CZ  . ARG A 1 241 ? 56.88863  -10.33049 -33.54589 1.000 97.89881  ? 241 ARG A CZ  1 
ATOM   1860 N  NH1 . ARG A 1 241 ? 57.74921  -9.62332  -34.25985 1.000 96.26610  ? 241 ARG A NH1 1 
ATOM   1861 N  NH2 . ARG A 1 241 ? 55.63037  -10.43713 -33.96298 1.000 94.63288  ? 241 ARG A NH2 1 
ATOM   1862 N  N   . ARG A 1 242 ? 57.96065  -16.34888 -30.06581 1.000 83.74413  ? 242 ARG A N   1 
ATOM   1863 C  CA  . ARG A 1 242 ? 57.38918  -17.65370 -30.38200 1.000 86.61226  ? 242 ARG A CA  1 
ATOM   1864 C  C   . ARG A 1 242 ? 56.89904  -18.37293 -29.13080 1.000 91.34220  ? 242 ARG A C   1 
ATOM   1865 O  O   . ARG A 1 242 ? 55.81834  -18.97357 -29.14040 1.000 90.34742  ? 242 ARG A O   1 
ATOM   1866 C  CB  . ARG A 1 242 ? 58.41269  -18.51978 -31.11834 1.000 80.35419  ? 242 ARG A CB  1 
ATOM   1867 C  CG  . ARG A 1 242 ? 58.96947  -17.89435 -32.38488 1.000 77.41917  ? 242 ARG A CG  1 
ATOM   1868 C  CD  . ARG A 1 242 ? 59.65525  -18.93459 -33.25725 1.000 83.32782  ? 242 ARG A CD  1 
ATOM   1869 N  NE  . ARG A 1 242 ? 60.78014  -19.57394 -32.58518 1.000 80.91279  ? 242 ARG A NE  1 
ATOM   1870 C  CZ  . ARG A 1 242 ? 62.04392  -19.19433 -32.71617 1.000 76.82364  ? 242 ARG A CZ  1 
ATOM   1871 N  NH1 . ARG A 1 242 ? 62.38228  -18.16966 -33.48186 1.000 73.90159  ? 242 ARG A NH1 1 
ATOM   1872 N  NH2 . ARG A 1 242 ? 62.99257  -19.86157 -32.06548 1.000 73.90684  ? 242 ARG A NH2 1 
ATOM   1873 N  N   . GLU A 1 243 ? 57.67710  -18.32083 -28.04782 1.000 88.49837  ? 243 GLU A N   1 
ATOM   1874 C  CA  . GLU A 1 243 ? 57.31328  -19.04953 -26.83656 1.000 87.14995  ? 243 GLU A CA  1 
ATOM   1875 C  C   . GLU A 1 243 ? 56.11270  -18.41789 -26.14101 1.000 86.98864  ? 243 GLU A C   1 
ATOM   1876 O  O   . GLU A 1 243 ? 55.24656  -19.13005 -25.61890 1.000 84.84937  ? 243 GLU A O   1 
ATOM   1877 C  CB  . GLU A 1 243 ? 58.50908  -19.11121 -25.88556 1.000 88.59103  ? 243 GLU A CB  1 
ATOM   1878 C  CG  . GLU A 1 243 ? 58.26904  -19.92996 -24.63211 1.000 81.99029  ? 243 GLU A CG  1 
ATOM   1879 C  CD  . GLU A 1 243 ? 59.42195  -19.84620 -23.65115 1.000 87.70227  ? 243 GLU A CD  1 
ATOM   1880 O  OE1 . GLU A 1 243 ? 60.36550  -19.06480 -23.90123 1.000 81.35371  ? 243 GLU A OE1 1 
ATOM   1881 O  OE2 . GLU A 1 243 ? 59.38555  -20.56591 -22.63055 1.000 81.41791  ? 243 GLU A OE2 1 
ATOM   1882 N  N   . HIS A 1 244 ? 56.03904  -17.08704 -26.12645 1.000 91.39989  ? 244 HIS A N   1 
ATOM   1883 C  CA  . HIS A 1 244 ? 55.00098  -16.37151 -25.39642 1.000 90.17630  ? 244 HIS A CA  1 
ATOM   1884 C  C   . HIS A 1 244 ? 54.03125  -15.61994 -26.29915 1.000 90.26848  ? 244 HIS A C   1 
ATOM   1885 O  O   . HIS A 1 244 ? 53.08300  -15.01228 -25.79097 1.000 94.84275  ? 244 HIS A O   1 
ATOM   1886 C  CB  . HIS A 1 244 ? 55.63948  -15.39537 -24.39984 1.000 87.87889  ? 244 HIS A CB  1 
ATOM   1887 C  CG  . HIS A 1 244 ? 56.58331  -16.04789 -23.43808 1.000 89.28400  ? 244 HIS A CG  1 
ATOM   1888 N  ND1 . HIS A 1 244 ? 56.32564  -17.27062 -22.85631 1.000 91.10986  ? 244 HIS A ND1 1 
ATOM   1889 C  CD2 . HIS A 1 244 ? 57.78876  -15.65299 -22.96415 1.000 88.02273  ? 244 HIS A CD2 1 
ATOM   1890 C  CE1 . HIS A 1 244 ? 57.32857  -17.59834 -22.06127 1.000 87.86510  ? 244 HIS A CE1 1 
ATOM   1891 N  NE2 . HIS A 1 244 ? 58.23004  -16.63408 -22.10935 1.000 91.71048  ? 244 HIS A NE2 1 
ATOM   1892 N  N   . GLY A 1 245 ? 54.23549  -15.64168 -27.61265 1.000 88.19372  ? 245 GLY A N   1 
ATOM   1893 C  CA  . GLY A 1 245 ? 53.32456  -14.95140 -28.51504 1.000 90.01910  ? 245 GLY A CA  1 
ATOM   1894 C  C   . GLY A 1 245 ? 53.25037  -13.45681 -28.29116 1.000 92.67325  ? 245 GLY A C   1 
ATOM   1895 O  O   . GLY A 1 245 ? 52.16957  -12.86566 -28.40691 1.000 92.89769  ? 245 GLY A O   1 
ATOM   1896 N  N   . TRP A 1 246 ? 54.37548  -12.83087 -27.96786 1.000 99.25428  ? 246 TRP A N   1 
ATOM   1897 C  CA  . TRP A 1 246 ? 54.42875  -11.40147 -27.70552 1.000 98.39526  ? 246 TRP A CA  1 
ATOM   1898 C  C   . TRP A 1 246 ? 55.01364  -10.66083 -28.90437 1.000 89.23969  ? 246 TRP A C   1 
ATOM   1899 O  O   . TRP A 1 246 ? 55.56551  -11.25679 -29.83223 1.000 90.50064  ? 246 TRP A O   1 
ATOM   1900 C  CB  . TRP A 1 246 ? 55.24968  -11.11891 -26.44271 1.000 89.92765  ? 246 TRP A CB  1 
ATOM   1901 N  N   . SER A 1 247 ? 54.88597  -9.33721  -28.87160 1.000 86.63360  ? 247 SER A N   1 
ATOM   1902 C  CA  . SER A 1 247 ? 55.38536  -8.49012  -29.94595 1.000 87.14780  ? 247 SER A CA  1 
ATOM   1903 C  C   . SER A 1 247 ? 56.89855  -8.32729  -29.81131 1.000 91.70346  ? 247 SER A C   1 
ATOM   1904 O  O   . SER A 1 247 ? 57.56021  -9.01153  -29.02572 1.000 90.26087  ? 247 SER A O   1 
ATOM   1905 C  CB  . SER A 1 247 ? 54.66900  -7.14212  -29.93629 1.000 85.54430  ? 247 SER A CB  1 
ATOM   1906 O  OG  . SER A 1 247 ? 54.98152  -6.40406  -28.76705 1.000 85.33066  ? 247 SER A OG  1 
ATOM   1907 N  N   . LYS A 1 248 ? 57.46525  -7.40509  -30.58925 1.000 94.44754  ? 248 LYS A N   1 
ATOM   1908 C  CA  . LYS A 1 248 ? 58.89614  -7.14030  -30.50786 1.000 84.00655  ? 248 LYS A CA  1 
ATOM   1909 C  C   . LYS A 1 248 ? 59.21800  -6.17440  -29.37393 1.000 90.28198  ? 248 LYS A C   1 
ATOM   1910 O  O   . LYS A 1 248 ? 60.21657  -6.35306  -28.66732 1.000 86.97509  ? 248 LYS A O   1 
ATOM   1911 C  CB  . LYS A 1 248 ? 59.39835  -6.59359  -31.84488 1.000 84.65774  ? 248 LYS A CB  1 
ATOM   1912 C  CG  . LYS A 1 248 ? 60.86973  -6.21679  -31.86817 1.000 87.53336  ? 248 LYS A CG  1 
ATOM   1913 C  CD  . LYS A 1 248 ? 61.30949  -5.84954  -33.27762 1.000 81.40163  ? 248 LYS A CD  1 
ATOM   1914 C  CE  . LYS A 1 248 ? 62.69787  -5.23688  -33.28569 1.000 85.65380  ? 248 LYS A CE  1 
ATOM   1915 N  NZ  . LYS A 1 248 ? 62.74175  -3.96859  -32.50645 1.000 90.18101  ? 248 LYS A NZ  1 
ATOM   1916 N  N   . SER A 1 249 ? 58.37646  -5.15606  -29.17651 1.000 88.67801  ? 249 SER A N   1 
ATOM   1917 C  CA  . SER A 1 249 ? 58.63283  -4.17705  -28.12590 1.000 85.77324  ? 249 SER A CA  1 
ATOM   1918 C  C   . SER A 1 249 ? 58.42966  -4.77107  -26.73708 1.000 88.35028  ? 249 SER A C   1 
ATOM   1919 O  O   . SER A 1 249 ? 59.08384  -4.34118  -25.77985 1.000 82.90349  ? 249 SER A O   1 
ATOM   1920 C  CB  . SER A 1 249 ? 57.73556  -2.95501  -28.31955 1.000 86.39832  ? 249 SER A CB  1 
ATOM   1921 O  OG  . SER A 1 249 ? 58.07550  -1.92428  -27.40840 1.000 96.46690  ? 249 SER A OG  1 
ATOM   1922 N  N   . ARG A 1 250 ? 57.53268  -5.75133  -26.60383 1.000 88.44479  ? 250 ARG A N   1 
ATOM   1923 C  CA  . ARG A 1 250 ? 57.32889  -6.38787  -25.30678 1.000 81.37649  ? 250 ARG A CA  1 
ATOM   1924 C  C   . ARG A 1 250 ? 58.49489  -7.30241  -24.95252 1.000 83.10950  ? 250 ARG A C   1 
ATOM   1925 O  O   . ARG A 1 250 ? 58.94607  -7.32358  -23.80118 1.000 80.35869  ? 250 ARG A O   1 
ATOM   1926 C  CB  . ARG A 1 250 ? 56.01445  -7.16787  -25.30275 1.000 77.69396  ? 250 ARG A CB  1 
ATOM   1927 C  CG  . ARG A 1 250 ? 55.70316  -7.84614  -23.97772 1.000 85.42488  ? 250 ARG A CG  1 
ATOM   1928 C  CD  . ARG A 1 250 ? 54.37188  -8.57680  -24.02569 1.000 93.13958  ? 250 ARG A CD  1 
ATOM   1929 N  NE  . ARG A 1 250 ? 54.02407  -9.16755  -22.73878 1.000 102.19694 ? 250 ARG A NE  1 
ATOM   1930 C  CZ  . ARG A 1 250 ? 52.89771  -9.82406  -22.49668 1.000 105.76212 ? 250 ARG A CZ  1 
ATOM   1931 N  NH1 . ARG A 1 250 ? 51.98335  -9.99754  -23.43666 1.000 109.99975 ? 250 ARG A NH1 1 
ATOM   1932 N  NH2 . ARG A 1 250 ? 52.68240  -10.31743 -21.28056 1.000 97.99299  ? 250 ARG A NH2 1 
ATOM   1933 N  N   . SER A 1 251 ? 58.99679  -8.06397  -25.92943 1.000 79.65729  ? 251 SER A N   1 
ATOM   1934 C  CA  . SER A 1 251 ? 60.11505  -8.96406  -25.66780 1.000 77.95742  ? 251 SER A CA  1 
ATOM   1935 C  C   . SER A 1 251 ? 61.37386  -8.20107  -25.27803 1.000 76.67563  ? 251 SER A C   1 
ATOM   1936 O  O   . SER A 1 251 ? 62.16408  -8.68741  -24.46039 1.000 73.72371  ? 251 SER A O   1 
ATOM   1937 C  CB  . SER A 1 251 ? 60.38397  -9.84089  -26.89186 1.000 81.24534  ? 251 SER A CB  1 
ATOM   1938 O  OG  . SER A 1 251 ? 59.32188  -10.75216 -27.11466 1.000 81.15591  ? 251 SER A OG  1 
ATOM   1939 N  N   . VAL A 1 252 ? 61.57986  -7.01135  -25.84748 1.000 72.62226  ? 252 VAL A N   1 
ATOM   1940 C  CA  . VAL A 1 252 ? 62.74806  -6.21337  -25.48805 1.000 74.75357  ? 252 VAL A CA  1 
ATOM   1941 C  C   . VAL A 1 252 ? 62.60981  -5.67097  -24.07035 1.000 77.74179  ? 252 VAL A C   1 
ATOM   1942 O  O   . VAL A 1 252 ? 63.56888  -5.68907  -23.28900 1.000 74.51168  ? 252 VAL A O   1 
ATOM   1943 C  CB  . VAL A 1 252 ? 62.96147  -5.08514  -26.51381 1.000 76.17431  ? 252 VAL A CB  1 
ATOM   1944 C  CG1 . VAL A 1 252 ? 64.06274  -4.14531  -26.05263 1.000 67.26542  ? 252 VAL A CG1 1 
ATOM   1945 C  CG2 . VAL A 1 252 ? 63.30057  -5.66945  -27.87674 1.000 72.58892  ? 252 VAL A CG2 1 
ATOM   1946 N  N   . SER A 1 253 ? 61.41826  -5.18293  -23.71307 1.000 77.98783  ? 253 SER A N   1 
ATOM   1947 C  CA  . SER A 1 253 ? 61.19115  -4.72097  -22.34700 1.000 77.30285  ? 253 SER A CA  1 
ATOM   1948 C  C   . SER A 1 253 ? 61.31749  -5.86651  -21.35097 1.000 70.01503  ? 253 SER A C   1 
ATOM   1949 O  O   . SER A 1 253 ? 61.80158  -5.67325  -20.22970 1.000 66.45875  ? 253 SER A O   1 
ATOM   1950 C  CB  . SER A 1 253 ? 59.81749  -4.05927  -22.23348 1.000 78.38103  ? 253 SER A CB  1 
ATOM   1951 O  OG  . SER A 1 253 ? 59.81597  -2.77802  -22.83792 1.000 86.68687  ? 253 SER A OG  1 
ATOM   1952 N  N   . HIS A 1 254 ? 60.88884  -7.06889  -21.74243 1.000 67.56947  ? 254 HIS A N   1 
ATOM   1953 C  CA  . HIS A 1 254 ? 61.03999  -8.22331  -20.86394 1.000 67.75752  ? 254 HIS A CA  1 
ATOM   1954 C  C   . HIS A 1 254 ? 62.51045  -8.54186  -20.62507 1.000 69.64924  ? 254 HIS A C   1 
ATOM   1955 O  O   . HIS A 1 254 ? 62.89714  -8.93761  -19.51886 1.000 70.44995  ? 254 HIS A O   1 
ATOM   1956 C  CB  . HIS A 1 254 ? 60.31836  -9.43272  -21.45602 1.000 59.69428  ? 254 HIS A CB  1 
ATOM   1957 C  CG  . HIS A 1 254 ? 60.42901  -10.66904 -20.62040 1.000 63.00669  ? 254 HIS A CG  1 
ATOM   1958 N  ND1 . HIS A 1 254 ? 59.79836  -10.80234 -19.40221 1.000 64.14080  ? 254 HIS A ND1 1 
ATOM   1959 C  CD2 . HIS A 1 254 ? 61.09978  -11.82745 -20.82534 1.000 67.18837  ? 254 HIS A CD2 1 
ATOM   1960 C  CE1 . HIS A 1 254 ? 60.07416  -11.98994 -18.89334 1.000 65.62532  ? 254 HIS A CE1 1 
ATOM   1961 N  NE2 . HIS A 1 254 ? 60.86141  -12.63215 -19.73751 1.000 68.22907  ? 254 HIS A NE2 1 
ATOM   1962 N  N   . MET A 1 255 ? 63.34743  -8.36766  -21.64944 1.000 64.35817  ? 255 MET A N   1 
ATOM   1963 C  CA  . MET A 1 255 ? 64.77004  -8.64762  -21.50307 1.000 63.96151  ? 255 MET A CA  1 
ATOM   1964 C  C   . MET A 1 255 ? 65.48252  -7.56999  -20.69706 1.000 61.93769  ? 255 MET A C   1 
ATOM   1965 O  O   . MET A 1 255 ? 66.47672  -7.86440  -20.02458 1.000 62.17416  ? 255 MET A O   1 
ATOM   1966 C  CB  . MET A 1 255 ? 65.41387  -8.80806  -22.88080 1.000 63.14933  ? 255 MET A CB  1 
ATOM   1967 C  CG  . MET A 1 255 ? 64.98791  -10.08198 -23.59185 1.000 62.20429  ? 255 MET A CG  1 
ATOM   1968 S  SD  . MET A 1 255 ? 65.37789  -10.09798 -25.35034 1.000 60.07869  ? 255 MET A SD  1 
ATOM   1969 C  CE  . MET A 1 255 ? 67.16655  -10.01973 -25.31423 1.000 48.72765  ? 255 MET A CE  1 
ATOM   1970 N  N   . GLN A 1 256 ? 64.99749  -6.32733  -20.74621 1.000 64.17540  ? 256 GLN A N   1 
ATOM   1971 C  CA  . GLN A 1 256 ? 65.53701  -5.29547  -19.86717 1.000 57.76307  ? 256 GLN A CA  1 
ATOM   1972 C  C   . GLN A 1 256 ? 65.21953  -5.60659  -18.41090 1.000 59.85681  ? 256 GLN A C   1 
ATOM   1973 O  O   . GLN A 1 256 ? 66.09409  -5.51987  -17.54110 1.000 58.59477  ? 256 GLN A O   1 
ATOM   1974 C  CB  . GLN A 1 256 ? 64.98124  -3.92511  -20.25199 1.000 57.52835  ? 256 GLN A CB  1 
ATOM   1975 C  CG  . GLN A 1 256 ? 65.58061  -3.32646  -21.50990 1.000 72.62499  ? 256 GLN A CG  1 
ATOM   1976 C  CD  . GLN A 1 256 ? 65.00476  -1.95861  -21.82776 1.000 75.22486  ? 256 GLN A CD  1 
ATOM   1977 O  OE1 . GLN A 1 256 ? 63.78982  -1.75529  -21.77803 1.000 67.48983  ? 256 GLN A OE1 1 
ATOM   1978 N  NE2 . GLN A 1 256 ? 65.87740  -1.00970  -22.14797 1.000 76.05877  ? 256 GLN A NE2 1 
ATOM   1979 N  N   . ASN A 1 257 ? 63.96553  -5.97045  -18.12867 1.000 59.63559  ? 257 ASN A N   1 
ATOM   1980 C  CA  . ASN A 1 257 ? 63.57750  -6.30141  -16.76238 1.000 58.31928  ? 257 ASN A CA  1 
ATOM   1981 C  C   . ASN A 1 257 ? 64.34629  -7.51087  -16.24997 1.000 58.56914  ? 257 ASN A C   1 
ATOM   1982 O  O   . ASN A 1 257 ? 64.71823  -7.56422  -15.07195 1.000 56.19781  ? 257 ASN A O   1 
ATOM   1983 C  CB  . ASN A 1 257 ? 62.07156  -6.55354  -16.68966 1.000 62.54246  ? 257 ASN A CB  1 
ATOM   1984 C  CG  . ASN A 1 257 ? 61.25432  -5.33601  -17.09099 1.000 73.22107  ? 257 ASN A CG  1 
ATOM   1985 O  OD1 . ASN A 1 257 ? 61.74808  -4.20657  -17.07331 1.000 68.39983  ? 257 ASN A OD1 1 
ATOM   1986 N  ND2 . ASN A 1 257 ? 59.99404  -5.56088  -17.44771 1.000 73.30415  ? 257 ASN A ND2 1 
ATOM   1987 N  N   . GLU A 1 258 ? 64.59743  -8.49216  -17.12087 1.000 58.32566  ? 258 GLU A N   1 
ATOM   1988 C  CA  . GLU A 1 258 ? 65.36311  -9.66178  -16.70385 1.000 52.91117  ? 258 GLU A CA  1 
ATOM   1989 C  C   . GLU A 1 258 ? 66.80508  -9.28899  -16.38274 1.000 48.21453  ? 258 GLU A C   1 
ATOM   1990 O  O   . GLU A 1 258 ? 67.38447  -9.80896  -15.42380 1.000 51.83347  ? 258 GLU A O   1 
ATOM   1991 C  CB  . GLU A 1 258 ? 65.30389  -10.74539 -17.78126 1.000 58.43947  ? 258 GLU A CB  1 
ATOM   1992 C  CG  . GLU A 1 258 ? 63.95415  -11.45378 -17.87373 1.000 59.79986  ? 258 GLU A CG  1 
ATOM   1993 C  CD  . GLU A 1 258 ? 63.58051  -12.18596 -16.59271 1.000 70.85311  ? 258 GLU A CD  1 
ATOM   1994 O  OE1 . GLU A 1 258 ? 64.47921  -12.77486 -15.95497 1.000 72.31327  ? 258 GLU A OE1 1 
ATOM   1995 O  OE2 . GLU A 1 258 ? 62.38757  -12.16950 -16.21889 1.000 74.35964  ? 258 GLU A OE2 1 
ATOM   1996 N  N   . VAL A 1 259 ? 67.39768  -8.38096  -17.16129 1.000 47.33916  ? 259 VAL A N   1 
ATOM   1997 C  CA  . VAL A 1 259 ? 68.73765  -7.90014  -16.83649 1.000 48.02870  ? 259 VAL A CA  1 
ATOM   1998 C  C   . VAL A 1 259 ? 68.72926  -7.17991  -15.49472 1.000 52.21773  ? 259 VAL A C   1 
ATOM   1999 O  O   . VAL A 1 259 ? 69.62594  -7.37211  -14.66283 1.000 52.64184  ? 259 VAL A O   1 
ATOM   2000 C  CB  . VAL A 1 259 ? 69.27673  -6.99830  -17.96248 1.000 54.90577  ? 259 VAL A CB  1 
ATOM   2001 C  CG1 . VAL A 1 259 ? 70.50787  -6.24426  -17.48818 1.000 50.32540  ? 259 VAL A CG1 1 
ATOM   2002 C  CG2 . VAL A 1 259 ? 69.60779  -7.82838  -19.19542 1.000 49.54188  ? 259 VAL A CG2 1 
ATOM   2003 N  N   . ARG A 1 260 ? 67.71108  -6.34932  -15.25744 1.000 52.49501  ? 260 ARG A N   1 
ATOM   2004 C  CA  . ARG A 1 260 ? 67.60766  -5.64605  -13.98249 1.000 53.79635  ? 260 ARG A CA  1 
ATOM   2005 C  C   . ARG A 1 260 ? 67.43374  -6.62491  -12.82678 1.000 49.38041  ? 260 ARG A C   1 
ATOM   2006 O  O   . ARG A 1 260 ? 68.13843  -6.53945  -11.81376 1.000 45.64201  ? 260 ARG A O   1 
ATOM   2007 C  CB  . ARG A 1 260 ? 66.44664  -4.65260  -14.02387 1.000 57.21369  ? 260 ARG A CB  1 
ATOM   2008 C  CG  . ARG A 1 260 ? 66.10033  -4.06782  -12.66082 1.000 55.64056  ? 260 ARG A CG  1 
ATOM   2009 C  CD  . ARG A 1 260 ? 64.95350  -3.07729  -12.75005 1.000 64.73244  ? 260 ARG A CD  1 
ATOM   2010 N  NE  . ARG A 1 260 ? 65.28887  -1.92832  -13.58275 1.000 73.78339  ? 260 ARG A NE  1 
ATOM   2011 C  CZ  . ARG A 1 260 ? 65.94318  -0.85771  -13.15258 1.000 73.30990  ? 260 ARG A CZ  1 
ATOM   2012 N  NH1 . ARG A 1 260 ? 66.35789  -0.75763  -11.90032 1.000 67.78083  ? 260 ARG A NH1 1 
ATOM   2013 N  NH2 . ARG A 1 260 ? 66.18953  0.13687   -14.00068 1.000 74.94459  ? 260 ARG A NH2 1 
ATOM   2014 N  N   . ALA A 1 261 ? 66.49641  -7.56735  -12.96524 1.000 47.17779  ? 261 ALA A N   1 
ATOM   2015 C  CA  . ALA A 1 261 ? 66.24483  -8.52925  -11.89692 1.000 47.65680  ? 261 ALA A CA  1 
ATOM   2016 C  C   . ALA A 1 261 ? 67.49057  -9.34605  -11.57879 1.000 46.41116  ? 261 ALA A C   1 
ATOM   2017 O  O   . ALA A 1 261 ? 67.78564  -9.61033  -10.40764 1.000 47.37668  ? 261 ALA A O   1 
ATOM   2018 C  CB  . ALA A 1 261 ? 65.08513  -9.44763  -12.28086 1.000 44.48791  ? 261 ALA A CB  1 
ATOM   2019 N  N   . ARG A 1 262 ? 68.24192  -9.74564  -12.60615 1.000 43.24494  ? 262 ARG A N   1 
ATOM   2020 C  CA  . ARG A 1 262 ? 69.43230  -10.55479 -12.36710 1.000 47.84111  ? 262 ARG A CA  1 
ATOM   2021 C  C   . ARG A 1 262 ? 70.55718  -9.72669  -11.75928 1.000 44.35754  ? 262 ARG A C   1 
ATOM   2022 O  O   . ARG A 1 262 ? 71.33720  -10.23785 -10.94569 1.000 45.17007  ? 262 ARG A O   1 
ATOM   2023 C  CB  . ARG A 1 262 ? 69.88347  -11.22595 -13.66419 1.000 45.51908  ? 262 ARG A CB  1 
ATOM   2024 C  CG  . ARG A 1 262 ? 68.84244  -12.18455 -14.21920 1.000 50.06503  ? 262 ARG A CG  1 
ATOM   2025 C  CD  . ARG A 1 262 ? 69.39221  -13.09004 -15.30831 1.000 53.88381  ? 262 ARG A CD  1 
ATOM   2026 N  NE  . ARG A 1 262 ? 68.31669  -13.72641 -16.06053 1.000 62.16580  ? 262 ARG A NE  1 
ATOM   2027 C  CZ  . ARG A 1 262 ? 67.53903  -14.69544 -15.59301 1.000 77.58378  ? 262 ARG A CZ  1 
ATOM   2028 N  NH1 . ARG A 1 262 ? 67.68398  -15.17405 -14.36608 1.000 66.96681  ? 262 ARG A NH1 1 
ATOM   2029 N  NH2 . ARG A 1 262 ? 66.58619  -15.19449 -16.37375 1.000 77.43661  ? 262 ARG A NH2 1 
ATOM   2030 N  N   . LEU A 1 263 ? 70.66055  -8.44917  -12.13720 1.000 42.30742  ? 263 LEU A N   1 
ATOM   2031 C  CA  . LEU A 1 263 ? 71.66537  -7.58784  -11.51986 1.000 43.28440  ? 263 LEU A CA  1 
ATOM   2032 C  C   . LEU A 1 263 ? 71.34013  -7.32758  -10.05432 1.000 45.98395  ? 263 LEU A C   1 
ATOM   2033 O  O   . LEU A 1 263 ? 72.24635  -7.24473  -9.21653  1.000 40.53352  ? 263 LEU A O   1 
ATOM   2034 C  CB  . LEU A 1 263 ? 71.78669  -6.26943  -12.28445 1.000 43.94482  ? 263 LEU A CB  1 
ATOM   2035 C  CG  . LEU A 1 263 ? 73.02900  -6.13666  -13.17066 1.000 49.98731  ? 263 LEU A CG  1 
ATOM   2036 C  CD1 . LEU A 1 263 ? 74.28720  -6.31708  -12.34195 1.000 52.57170  ? 263 LEU A CD1 1 
ATOM   2037 C  CD2 . LEU A 1 263 ? 72.99427  -7.14418  -14.30162 1.000 46.85379  ? 263 LEU A CD2 1 
ATOM   2038 N  N   . GLU A 1 264 ? 70.05262  -7.19667  -9.72521  1.000 44.66165  ? 264 GLU A N   1 
ATOM   2039 C  CA  . GLU A 1 264 ? 69.66430  -7.06188  -8.32507  1.000 49.92988  ? 264 GLU A CA  1 
ATOM   2040 C  C   . GLU A 1 264 ? 69.98672  -8.32967  -7.54857  1.000 45.69732  ? 264 GLU A C   1 
ATOM   2041 O  O   . GLU A 1 264 ? 70.51280  -8.26694  -6.43155  1.000 46.41895  ? 264 GLU A O   1 
ATOM   2042 C  CB  . GLU A 1 264 ? 68.17583  -6.72988  -8.21492  1.000 48.59163  ? 264 GLU A CB  1 
ATOM   2043 C  CG  . GLU A 1 264 ? 67.82371  -5.32695  -8.66316  1.000 55.17592  ? 264 GLU A CG  1 
ATOM   2044 C  CD  . GLU A 1 264 ? 68.58456  -4.26839  -7.88925  1.000 71.71390  ? 264 GLU A CD  1 
ATOM   2045 O  OE1 . GLU A 1 264 ? 68.74695  -4.42419  -6.65767  1.000 76.21253  ? 264 GLU A OE1 1 
ATOM   2046 O  OE2 . GLU A 1 264 ? 69.02851  -3.28223  -8.51427  1.000 74.12982  ? 264 GLU A OE2 1 
ATOM   2047 N  N   . GLN A 1 265 ? 69.68493  -9.49278  -8.13002  1.000 47.41725  ? 265 GLN A N   1 
ATOM   2048 C  CA  . GLN A 1 265 ? 70.03467  -10.75204 -7.48335  1.000 42.65036  ? 265 GLN A CA  1 
ATOM   2049 C  C   . GLN A 1 265 ? 71.54399  -10.91620 -7.38211  1.000 43.42318  ? 265 GLN A C   1 
ATOM   2050 O  O   . GLN A 1 265 ? 72.04846  -11.47290 -6.39901  1.000 41.77962  ? 265 GLN A O   1 
ATOM   2051 C  CB  . GLN A 1 265 ? 69.41543  -11.92271 -8.24295  1.000 39.71237  ? 265 GLN A CB  1 
ATOM   2052 C  CG  . GLN A 1 265 ? 67.90350  -11.96753 -8.16795  1.000 44.49171  ? 265 GLN A CG  1 
ATOM   2053 C  CD  . GLN A 1 265 ? 67.30876  -13.01175 -9.08833  1.000 48.49119  ? 265 GLN A CD  1 
ATOM   2054 O  OE1 . GLN A 1 265 ? 67.37259  -14.20940 -8.81261  1.000 46.98750  ? 265 GLN A OE1 1 
ATOM   2055 N  NE2 . GLN A 1 265 ? 66.72619  -12.56190 -10.19191 1.000 49.76592  ? 265 GLN A NE2 1 
ATOM   2056 N  N   . TYR A 1 266 ? 72.28239  -10.43155 -8.38722  1.000 44.09311  ? 266 TYR A N   1 
ATOM   2057 C  CA  . TYR A 1 266 ? 73.73825  -10.50341 -8.32819  1.000 42.83112  ? 266 TYR A CA  1 
ATOM   2058 C  C   . TYR A 1 266 ? 74.27442  -9.77225  -7.10323  1.000 46.12389  ? 266 TYR A C   1 
ATOM   2059 O  O   . TYR A 1 266 ? 75.22362  -10.23631 -6.45900  1.000 44.14989  ? 266 TYR A O   1 
ATOM   2060 C  CB  . TYR A 1 266 ? 74.36743  -9.93181  -9.60342  1.000 40.63956  ? 266 TYR A CB  1 
ATOM   2061 C  CG  . TYR A 1 266 ? 75.86966  -9.88821  -9.48854  1.000 42.89436  ? 266 TYR A CG  1 
ATOM   2062 C  CD1 . TYR A 1 266 ? 76.62653  -11.03673 -9.66999  1.000 45.29690  ? 266 TYR A CD1 1 
ATOM   2063 C  CD2 . TYR A 1 266 ? 76.52879  -8.71654  -9.13875  1.000 41.94868  ? 266 TYR A CD2 1 
ATOM   2064 C  CE1 . TYR A 1 266 ? 78.00280  -11.01742 -9.53253  1.000 46.68046  ? 266 TYR A CE1 1 
ATOM   2065 C  CE2 . TYR A 1 266 ? 77.90644  -8.68650  -8.99831  1.000 43.70315  ? 266 TYR A CE2 1 
ATOM   2066 C  CZ  . TYR A 1 266 ? 78.63868  -9.84127  -9.19503  1.000 48.99776  ? 266 TYR A CZ  1 
ATOM   2067 O  OH  . TYR A 1 266 ? 80.00821  -9.82529  -9.05595  1.000 46.55463  ? 266 TYR A OH  1 
ATOM   2068 N  N   . LEU A 1 267 ? 73.68091  -8.62362  -6.76841  1.000 44.54523  ? 267 LEU A N   1 
ATOM   2069 C  CA  . LEU A 1 267 ? 74.12075  -7.88324  -5.59078  1.000 43.00973  ? 267 LEU A CA  1 
ATOM   2070 C  C   . LEU A 1 267 ? 73.80217  -8.64611  -4.31120  1.000 40.59529  ? 267 LEU A C   1 
ATOM   2071 O  O   . LEU A 1 267 ? 74.61394  -8.66722  -3.37846  1.000 43.11553  ? 267 LEU A O   1 
ATOM   2072 C  CB  . LEU A 1 267 ? 73.47859  -6.49659  -5.57372  1.000 44.17455  ? 267 LEU A CB  1 
ATOM   2073 C  CG  . LEU A 1 267 ? 73.85048  -5.57061  -6.73493  1.000 49.02821  ? 267 LEU A CG  1 
ATOM   2074 C  CD1 . LEU A 1 267 ? 73.05656  -4.27819  -6.65819  1.000 51.67251  ? 267 LEU A CD1 1 
ATOM   2075 C  CD2 . LEU A 1 267 ? 75.34489  -5.28148  -6.73548  1.000 41.47314  ? 267 LEU A CD2 1 
ATOM   2076 N  N   . LEU A 1 268 ? 72.62855  -9.28147  -4.25003  1.000 43.70396  ? 268 LEU A N   1 
ATOM   2077 C  CA  . LEU A 1 268 ? 72.30352  -10.13237 -3.10781  1.000 44.89101  ? 268 LEU A CA  1 
ATOM   2078 C  C   . LEU A 1 268 ? 73.33645  -11.23757 -2.93924  1.000 45.36285  ? 268 LEU A C   1 
ATOM   2079 O  O   . LEU A 1 268 ? 73.79916  -11.50728 -1.82467  1.000 47.46920  ? 268 LEU A O   1 
ATOM   2080 C  CB  . LEU A 1 268 ? 70.91168  -10.74322 -3.27475  1.000 43.77992  ? 268 LEU A CB  1 
ATOM   2081 C  CG  . LEU A 1 268 ? 69.68287  -9.83853  -3.26944  1.000 57.24635  ? 268 LEU A CG  1 
ATOM   2082 C  CD1 . LEU A 1 268 ? 68.41926  -10.69066 -3.30835  1.000 53.59678  ? 268 LEU A CD1 1 
ATOM   2083 C  CD2 . LEU A 1 268 ? 69.69263  -8.92896  -2.05215  1.000 53.35195  ? 268 LEU A CD2 1 
ATOM   2084 N  N   . LEU A 1 269 ? 73.70386  -11.89557 -4.04332  1.000 43.17671  ? 269 LEU A N   1 
ATOM   2085 C  CA  . LEU A 1 269 ? 74.64555  -13.00784 -3.97017  1.000 43.40250  ? 269 LEU A CA  1 
ATOM   2086 C  C   . LEU A 1 269 ? 76.02885  -12.53993 -3.53534  1.000 41.17166  ? 269 LEU A C   1 
ATOM   2087 O  O   . LEU A 1 269 ? 76.72483  -13.24987 -2.79958  1.000 41.87757  ? 269 LEU A O   1 
ATOM   2088 C  CB  . LEU A 1 269 ? 74.70839  -13.72161 -5.32011  1.000 43.88253  ? 269 LEU A CB  1 
ATOM   2089 C  CG  . LEU A 1 269 ? 73.39664  -14.41263 -5.70270  1.000 44.01797  ? 269 LEU A CG  1 
ATOM   2090 C  CD1 . LEU A 1 269 ? 73.39422  -14.84950 -7.15242  1.000 39.60671  ? 269 LEU A CD1 1 
ATOM   2091 C  CD2 . LEU A 1 269 ? 73.14998  -15.60345 -4.79164  1.000 46.11498  ? 269 LEU A CD2 1 
ATOM   2092 N  N   . GLU A 1 270 ? 76.44474  -11.35022 -3.97838  1.000 39.96895  ? 270 GLU A N   1 
ATOM   2093 C  CA  . GLU A 1 270 ? 77.72398  -10.80135 -3.53555  1.000 42.29013  ? 270 GLU A CA  1 
ATOM   2094 C  C   . GLU A 1 270 ? 77.76602  -10.64201 -2.02254  1.000 42.51840  ? 270 GLU A C   1 
ATOM   2095 O  O   . GLU A 1 270 ? 78.79217  -10.91948 -1.39011  1.000 42.92686  ? 270 GLU A O   1 
ATOM   2096 C  CB  . GLU A 1 270 ? 77.98763  -9.45480  -4.20746  1.000 45.20937  ? 270 GLU A CB  1 
ATOM   2097 C  CG  . GLU A 1 270 ? 78.73151  -9.53576  -5.52431  1.000 47.56129  ? 270 GLU A CG  1 
ATOM   2098 C  CD  . GLU A 1 270 ? 79.13212  -8.16508  -6.03276  1.000 50.71649  ? 270 GLU A CD  1 
ATOM   2099 O  OE1 . GLU A 1 270 ? 78.50582  -7.17300  -5.60357  1.000 48.38429  ? 270 GLU A OE1 1 
ATOM   2100 O  OE2 . GLU A 1 270 ? 80.07075  -8.07726  -6.85505  1.000 46.41091  ? 270 GLU A OE2 1 
ATOM   2101 N  N   . SER A 1 271 ? 76.66211  -10.19185 -1.42411  1.000 40.32639  ? 271 SER A N   1 
ATOM   2102 C  CA  . SER A 1 271 ? 76.62572  -9.98180  0.01680   1.000 45.62590  ? 271 SER A CA  1 
ATOM   2103 C  C   . SER A 1 271 ? 76.71731  -11.28414 0.79997   1.000 48.17128  ? 271 SER A C   1 
ATOM   2104 O  O   . SER A 1 271 ? 76.94657  -11.24032 2.01271   1.000 52.08752  ? 271 SER A O   1 
ATOM   2105 C  CB  . SER A 1 271 ? 75.35254  -9.22649  0.40696   1.000 38.30853  ? 271 SER A CB  1 
ATOM   2106 O  OG  . SER A 1 271 ? 74.21313  -10.06621 0.34633   1.000 46.57915  ? 271 SER A OG  1 
ATOM   2107 N  N   . CYS A 1 272 ? 76.54870  -12.43161 0.14266   1.000 44.35747  ? 272 CYS A N   1 
ATOM   2108 C  CA  . CYS A 1 272 ? 76.67078  -13.73004 0.79065   1.000 39.76948  ? 272 CYS A CA  1 
ATOM   2109 C  C   . CYS A 1 272 ? 78.09601  -14.26502 0.80047   1.000 43.18081  ? 272 CYS A C   1 
ATOM   2110 O  O   . CYS A 1 272 ? 78.36189  -15.25737 1.48825   1.000 44.75073  ? 272 CYS A O   1 
ATOM   2111 C  CB  . CYS A 1 272 ? 75.76497  -14.75618 0.10070   1.000 41.70563  ? 272 CYS A CB  1 
ATOM   2112 S  SG  . CYS A 1 272 ? 73.99786  -14.40546 0.20085   1.000 51.36480  ? 272 CYS A SG  1 
ATOM   2113 N  N   . LEU A 1 273 ? 79.01210  -13.63856 0.06410   1.000 40.07703  ? 273 LEU A N   1 
ATOM   2114 C  CA  . LEU A 1 273 ? 80.36067  -14.16745 -0.11595  1.000 38.72455  ? 273 LEU A CA  1 
ATOM   2115 C  C   . LEU A 1 273 ? 81.17144  -14.24315 1.17983   1.000 43.07472  ? 273 LEU A C   1 
ATOM   2116 O  O   . LEU A 1 273 ? 81.94896  -15.19265 1.34169   1.000 42.54034  ? 273 LEU A O   1 
ATOM   2117 C  CB  . LEU A 1 273 ? 81.11336  -13.34824 -1.16721  1.000 36.79558  ? 273 LEU A CB  1 
ATOM   2118 C  CG  . LEU A 1 273 ? 80.64566  -13.61713 -2.59979  1.000 43.87054  ? 273 LEU A CG  1 
ATOM   2119 C  CD1 . LEU A 1 273 ? 81.49226  -12.85096 -3.60733  1.000 41.03786  ? 273 LEU A CD1 1 
ATOM   2120 C  CD2 . LEU A 1 273 ? 80.67070  -15.11461 -2.89349  1.000 37.31298  ? 273 LEU A CD2 1 
ATOM   2121 N  N   . PRO A 1 274 ? 81.05378  -13.28774 2.11767   1.000 44.53253  ? 274 PRO A N   1 
ATOM   2122 C  CA  . PRO A 1 274 ? 81.74554  -13.47820 3.40919   1.000 43.55521  ? 274 PRO A CA  1 
ATOM   2123 C  C   . PRO A 1 274 ? 81.31588  -14.74135 4.13874   1.000 42.45424  ? 274 PRO A C   1 
ATOM   2124 O  O   . PRO A 1 274 ? 82.16372  -15.46901 4.67034   1.000 40.83688  ? 274 PRO A O   1 
ATOM   2125 C  CB  . PRO A 1 274 ? 81.37584  -12.21022 4.19429   1.000 47.26869  ? 274 PRO A CB  1 
ATOM   2126 C  CG  . PRO A 1 274 ? 81.13231  -11.18518 3.14471   1.000 43.60408  ? 274 PRO A CG  1 
ATOM   2127 C  CD  . PRO A 1 274 ? 80.48476  -11.92992 2.00965   1.000 44.46194  ? 274 PRO A CD  1 
ATOM   2128 N  N   . LYS A 1 275 ? 80.01353  -15.02628 4.17334   1.000 40.77438  ? 275 LYS A N   1 
ATOM   2129 C  CA  . LYS A 1 275 ? 79.54574  -16.25291 4.80795   1.000 44.21122  ? 275 LYS A CA  1 
ATOM   2130 C  C   . LYS A 1 275 ? 79.92896  -17.48240 3.99237   1.000 43.99641  ? 275 LYS A C   1 
ATOM   2131 O  O   . LYS A 1 275 ? 80.18968  -18.55035 4.55869   1.000 39.85854  ? 275 LYS A O   1 
ATOM   2132 C  CB  . LYS A 1 275 ? 78.03448  -16.18896 5.01570   1.000 46.79692  ? 275 LYS A CB  1 
ATOM   2133 C  CG  . LYS A 1 275 ? 77.62237  -15.28808 6.17318   1.000 52.20939  ? 275 LYS A CG  1 
ATOM   2134 C  CD  . LYS A 1 275 ? 76.11168  -15.15094 6.26478   1.000 58.14296  ? 275 LYS A CD  1 
ATOM   2135 C  CE  . LYS A 1 275 ? 75.70035  -14.35411 7.49732   1.000 60.20297  ? 275 LYS A CE  1 
ATOM   2136 N  NZ  . LYS A 1 275 ? 74.22477  -14.15207 7.55763   1.000 67.70258  ? 275 LYS A NZ  1 
ATOM   2137 N  N   . VAL A 1 276 ? 79.96053  -17.35712 2.66205   1.000 38.89204  ? 276 VAL A N   1 
ATOM   2138 C  CA  . VAL A 1 276 ? 80.42791  -18.46278 1.82764   1.000 36.30306  ? 276 VAL A CA  1 
ATOM   2139 C  C   . VAL A 1 276 ? 81.88531  -18.77802 2.13639   1.000 34.01224  ? 276 VAL A C   1 
ATOM   2140 O  O   . VAL A 1 276 ? 82.28052  -19.94730 2.21594   1.000 39.52298  ? 276 VAL A O   1 
ATOM   2141 C  CB  . VAL A 1 276 ? 80.21773  -18.13802 0.33529   1.000 41.41637  ? 276 VAL A CB  1 
ATOM   2142 C  CG1 . VAL A 1 276 ? 80.94694  -19.14371 -0.55156  1.000 36.09975  ? 276 VAL A CG1 1 
ATOM   2143 C  CG2 . VAL A 1 276 ? 78.73089  -18.11433 0.00459   1.000 36.00307  ? 276 VAL A CG2 1 
ATOM   2144 N  N   . GLY A 1 277 ? 82.70516  -17.74267 2.32750   1.000 39.90936  ? 277 GLY A N   1 
ATOM   2145 C  CA  . GLY A 1 277 ? 84.09168  -17.97513 2.69428   1.000 36.85919  ? 277 GLY A CA  1 
ATOM   2146 C  C   . GLY A 1 277 ? 84.22446  -18.65583 4.04273   1.000 44.41051  ? 277 GLY A C   1 
ATOM   2147 O  O   . GLY A 1 277 ? 85.08922  -19.51354 4.23533   1.000 42.33747  ? 277 GLY A O   1 
ATOM   2148 N  N   . GLU A 1 278 ? 83.36353  -18.28619 4.99168   1.000 42.07794  ? 278 GLU A N   1 
ATOM   2149 C  CA  . GLU A 1 278 ? 83.34946  -18.95429 6.28798   1.000 46.52900  ? 278 GLU A CA  1 
ATOM   2150 C  C   . GLU A 1 278 ? 83.00069  -20.42904 6.13489   1.000 41.43229  ? 278 GLU A C   1 
ATOM   2151 O  O   . GLU A 1 278 ? 83.68487  -21.29966 6.68207   1.000 43.84316  ? 278 GLU A O   1 
ATOM   2152 C  CB  . GLU A 1 278 ? 82.35623  -18.25645 7.21789   1.000 46.57274  ? 278 GLU A CB  1 
ATOM   2153 C  CG  . GLU A 1 278 ? 82.29149  -18.83264 8.61959   1.000 54.46228  ? 278 GLU A CG  1 
ATOM   2154 C  CD  . GLU A 1 278 ? 81.35203  -18.05023 9.52221   1.000 64.54992  ? 278 GLU A CD  1 
ATOM   2155 O  OE1 . GLU A 1 278 ? 80.41401  -17.41431 8.99582   1.000 57.26411  ? 278 GLU A OE1 1 
ATOM   2156 O  OE2 . GLU A 1 278 ? 81.55505  -18.06404 10.75584  1.000 69.29134  ? 278 GLU A OE2 1 
ATOM   2157 N  N   . ILE A 1 279 ? 81.93804  -20.72310 5.37865   1.000 41.38860  ? 279 ILE A N   1 
ATOM   2158 C  CA  . ILE A 1 279 ? 81.49678  -22.10097 5.16262   1.000 37.97148  ? 279 ILE A CA  1 
ATOM   2159 C  C   . ILE A 1 279 ? 82.63238  -22.95951 4.61675   1.000 44.92165  ? 279 ILE A C   1 
ATOM   2160 O  O   . ILE A 1 279 ? 82.78676  -24.12740 4.99664   1.000 40.77347  ? 279 ILE A O   1 
ATOM   2161 C  CB  . ILE A 1 279 ? 80.27188  -22.11461 4.22782   1.000 44.37697  ? 279 ILE A CB  1 
ATOM   2162 C  CG1 . ILE A 1 279 ? 79.04865  -21.56451 4.96217   1.000 38.07836  ? 279 ILE A CG1 1 
ATOM   2163 C  CG2 . ILE A 1 279 ? 80.00831  -23.51192 3.68362   1.000 39.86267  ? 279 ILE A CG2 1 
ATOM   2164 C  CD1 . ILE A 1 279 ? 77.90010  -21.19390 4.05415   1.000 38.78274  ? 279 ILE A CD1 1 
ATOM   2165 N  N   . TYR A 1 280 ? 83.44939  -22.39639 3.72698   1.000 36.79897  ? 280 TYR A N   1 
ATOM   2166 C  CA  . TYR A 1 280 ? 84.57826  -23.11115 3.14297   1.000 41.29389  ? 280 TYR A CA  1 
ATOM   2167 C  C   . TYR A 1 280 ? 85.89077  -22.86445 3.88244   1.000 40.65782  ? 280 TYR A C   1 
ATOM   2168 O  O   . TYR A 1 280 ? 86.94509  -23.28839 3.39833   1.000 43.37242  ? 280 TYR A O   1 
ATOM   2169 C  CB  . TYR A 1 280 ? 84.72982  -22.74574 1.65948   1.000 39.32673  ? 280 TYR A CB  1 
ATOM   2170 C  CG  . TYR A 1 280 ? 83.67761  -23.38310 0.78094   1.000 41.61173  ? 280 TYR A CG  1 
ATOM   2171 C  CD1 . TYR A 1 280 ? 83.77426  -24.71841 0.41265   1.000 39.70253  ? 280 TYR A CD1 1 
ATOM   2172 C  CD2 . TYR A 1 280 ? 82.58019  -22.65728 0.33472   1.000 37.51404  ? 280 TYR A CD2 1 
ATOM   2173 C  CE1 . TYR A 1 280 ? 82.81087  -25.31322 -0.37787  1.000 36.17824  ? 280 TYR A CE1 1 
ATOM   2174 C  CE2 . TYR A 1 280 ? 81.61241  -23.24356 -0.45809  1.000 40.05597  ? 280 TYR A CE2 1 
ATOM   2175 C  CZ  . TYR A 1 280 ? 81.73386  -24.57143 -0.81113  1.000 41.96611  ? 280 TYR A CZ  1 
ATOM   2176 O  OH  . TYR A 1 280 ? 80.77640  -25.16002 -1.59984  1.000 45.93013  ? 280 TYR A OH  1 
ATOM   2177 N  N   . GLN A 1 281 ? 85.84758  -22.19760 5.03673   1.000 45.78164  ? 281 GLN A N   1 
ATOM   2178 C  CA  . GLN A 1 281 ? 87.01605  -22.01616 5.90234   1.000 49.01155  ? 281 GLN A CA  1 
ATOM   2179 C  C   . GLN A 1 281 ? 88.19505  -21.40759 5.14294   1.000 45.98196  ? 281 GLN A C   1 
ATOM   2180 O  O   . GLN A 1 281 ? 89.33482  -21.86932 5.23282   1.000 40.59177  ? 281 GLN A O   1 
ATOM   2181 C  CB  . GLN A 1 281 ? 87.41549  -23.33762 6.56270   1.000 46.01717  ? 281 GLN A CB  1 
ATOM   2182 C  CG  . GLN A 1 281 ? 86.35787  -23.91022 7.49007   1.000 52.13683  ? 281 GLN A CG  1 
ATOM   2183 C  CD  . GLN A 1 281 ? 86.80523  -25.19270 8.16260   1.000 60.43289  ? 281 GLN A CD  1 
ATOM   2184 O  OE1 . GLN A 1 281 ? 86.59512  -26.28738 7.63925   1.000 63.25698  ? 281 GLN A OE1 1 
ATOM   2185 N  NE2 . GLN A 1 281 ? 87.42824  -25.06349 9.32886   1.000 69.80147  ? 281 GLN A NE2 1 
ATOM   2186 N  N   . LEU A 1 282 ? 87.91042  -20.35532 4.38257   1.000 43.93546  ? 282 LEU A N   1 
ATOM   2187 C  CA  . LEU A 1 282 ? 88.96528  -19.65164 3.66791   1.000 45.40080  ? 282 LEU A CA  1 
ATOM   2188 C  C   . LEU A 1 282 ? 89.85836  -18.89862 4.64567   1.000 41.72206  ? 282 LEU A C   1 
ATOM   2189 O  O   . LEU A 1 282 ? 89.37659  -18.24870 5.57717   1.000 47.88291  ? 282 LEU A O   1 
ATOM   2190 C  CB  . LEU A 1 282 ? 88.36641  -18.67451 2.65504   1.000 40.13751  ? 282 LEU A CB  1 
ATOM   2191 C  CG  . LEU A 1 282 ? 87.46931  -19.24099 1.55204   1.000 42.25228  ? 282 LEU A CG  1 
ATOM   2192 C  CD1 . LEU A 1 282 ? 87.01952  -18.12628 0.61744   1.000 40.48363  ? 282 LEU A CD1 1 
ATOM   2193 C  CD2 . LEU A 1 282 ? 88.17872  -20.34808 0.77940   1.000 41.98953  ? 282 LEU A CD2 1 
ATOM   2194 N  N   . ASP A 1 283 ? 91.16782  -18.97899 4.42767   1.000 46.28819  ? 283 ASP A N   1 
ATOM   2195 C  CA  . ASP A 1 283 ? 92.08466  -18.16840 5.21187   1.000 53.83077  ? 283 ASP A CA  1 
ATOM   2196 C  C   . ASP A 1 283 ? 92.15043  -16.75506 4.62961   1.000 58.03195  ? 283 ASP A C   1 
ATOM   2197 O  O   . ASP A 1 283 ? 91.42345  -16.40475 3.69373   1.000 48.01197  ? 283 ASP A O   1 
ATOM   2198 C  CB  . ASP A 1 283 ? 93.46222  -18.83224 5.29215   1.000 48.67202  ? 283 ASP A CB  1 
ATOM   2199 C  CG  . ASP A 1 283 ? 94.13436  -18.99064 3.93836   1.000 58.30649  ? 283 ASP A CG  1 
ATOM   2200 O  OD1 . ASP A 1 283 ? 93.71212  -18.34470 2.95725   1.000 58.33705  ? 283 ASP A OD1 1 
ATOM   2201 O  OD2 . ASP A 1 283 ? 95.10555  -19.77458 3.85803   1.000 57.35454  ? 283 ASP A OD2 1 
ATOM   2202 N  N   . THR A 1 284 ? 93.03822  -15.93163 5.19378   1.000 55.46266  ? 284 THR A N   1 
ATOM   2203 C  CA  . THR A 1 284 ? 93.12725  -14.53322 4.78136   1.000 55.04360  ? 284 THR A CA  1 
ATOM   2204 C  C   . THR A 1 284 ? 93.48447  -14.41160 3.30401   1.000 53.08338  ? 284 THR A C   1 
ATOM   2205 O  O   . THR A 1 284 ? 92.85491  -13.64806 2.56341   1.000 53.13957  ? 284 THR A O   1 
ATOM   2206 C  CB  . THR A 1 284 ? 94.14957  -13.79413 5.64827   1.000 58.84911  ? 284 THR A CB  1 
ATOM   2207 O  OG1 . THR A 1 284 ? 93.61922  -13.61768 6.96793   1.000 49.55818  ? 284 THR A OG1 1 
ATOM   2208 C  CG2 . THR A 1 284 ? 94.47801  -12.42998 5.05099   1.000 52.69985  ? 284 THR A CG2 1 
ATOM   2209 N  N   . ALA A 1 285 ? 94.48923  -15.16683 2.85387   1.000 52.00291  ? 285 ALA A N   1 
ATOM   2210 C  CA  . ALA A 1 285 ? 94.90829  -15.08027 1.45859   1.000 52.43674  ? 285 ALA A CA  1 
ATOM   2211 C  C   . ALA A 1 285 ? 93.80163  -15.53599 0.51562   1.000 53.96731  ? 285 ALA A C   1 
ATOM   2212 O  O   . ALA A 1 285 ? 93.56565  -14.90994 -0.52377  1.000 56.55805  ? 285 ALA A O   1 
ATOM   2213 C  CB  . ALA A 1 285 ? 96.17320  -15.90836 1.23677   1.000 56.84875  ? 285 ALA A CB  1 
ATOM   2214 N  N   . GLU A 1 286 ? 93.11218  -16.62586 0.86041   1.000 49.46608  ? 286 GLU A N   1 
ATOM   2215 C  CA  . GLU A 1 286 ? 92.03767  -17.12141 0.00694   1.000 46.23236  ? 286 GLU A CA  1 
ATOM   2216 C  C   . GLU A 1 286 ? 90.88506  -16.12908 -0.06305  1.000 46.71670  ? 286 GLU A C   1 
ATOM   2217 O  O   . GLU A 1 286 ? 90.23680  -15.99379 -1.10751  1.000 46.64245  ? 286 GLU A O   1 
ATOM   2218 C  CB  . GLU A 1 286 ? 91.55033  -18.48032 0.51095   1.000 41.25452  ? 286 GLU A CB  1 
ATOM   2219 C  CG  . GLU A 1 286 ? 92.53689  -19.61580 0.27852   1.000 43.10998  ? 286 GLU A CG  1 
ATOM   2220 C  CD  . GLU A 1 286 ? 92.03175  -20.94844 0.80097   1.000 47.69219  ? 286 GLU A CD  1 
ATOM   2221 O  OE1 . GLU A 1 286 ? 91.58373  -21.00606 1.96690   1.000 49.88226  ? 286 GLU A OE1 1 
ATOM   2222 O  OE2 . GLU A 1 286 ? 92.07599  -21.93912 0.04146   1.000 51.71966  ? 286 GLU A OE2 1 
ATOM   2223 N  N   . ARG A 1 287 ? 90.61558  -15.42390 1.03827   1.000 45.40775  ? 287 ARG A N   1 
ATOM   2224 C  CA  . ARG A 1 287 ? 89.55663  -14.41983 1.02955   1.000 49.32937  ? 287 ARG A CA  1 
ATOM   2225 C  C   . ARG A 1 287 ? 89.89687  -13.26688 0.09428   1.000 46.42045  ? 287 ARG A C   1 
ATOM   2226 O  O   . ARG A 1 287 ? 89.01593  -12.73805 -0.59379  1.000 44.05880  ? 287 ARG A O   1 
ATOM   2227 C  CB  . ARG A 1 287 ? 89.30244  -13.90723 2.44688   1.000 49.43460  ? 287 ARG A CB  1 
ATOM   2228 C  CG  . ARG A 1 287 ? 88.62532  -14.92597 3.34423   1.000 54.53818  ? 287 ARG A CG  1 
ATOM   2229 C  CD  . ARG A 1 287 ? 88.31444  -14.36486 4.72096   1.000 55.02347  ? 287 ARG A CD  1 
ATOM   2230 N  NE  . ARG A 1 287 ? 86.99395  -14.79740 5.16067   1.000 63.11538  ? 287 ARG A NE  1 
ATOM   2231 C  CZ  . ARG A 1 287 ? 85.94492  -13.99705 5.29297   1.000 57.30205  ? 287 ARG A CZ  1 
ATOM   2232 N  NH1 . ARG A 1 287 ? 86.04264  -12.69068 5.10525   1.000 63.30527  ? 287 ARG A NH1 1 
ATOM   2233 N  NH2 . ARG A 1 287 ? 84.76921  -14.52002 5.62845   1.000 61.89954  ? 287 ARG A NH2 1 
ATOM   2234 N  N   . GLU A 1 288 ? 91.17022  -12.86288 0.05476   1.000 43.28646  ? 288 GLU A N   1 
ATOM   2235 C  CA  . GLU A 1 288 ? 91.58262  -11.81686 -0.87706  1.000 49.19559  ? 288 GLU A CA  1 
ATOM   2236 C  C   . GLU A 1 288 ? 91.48511  -12.29173 -2.32282  1.000 49.43484  ? 288 GLU A C   1 
ATOM   2237 O  O   . GLU A 1 288 ? 91.10407  -11.52003 -3.21065  1.000 50.06124  ? 288 GLU A O   1 
ATOM   2238 C  CB  . GLU A 1 288 ? 93.00605  -11.36053 -0.56427  1.000 47.21793  ? 288 GLU A CB  1 
ATOM   2239 C  CG  . GLU A 1 288 ? 93.15913  -10.66928 0.77653   1.000 66.86877  ? 288 GLU A CG  1 
ATOM   2240 C  CD  . GLU A 1 288 ? 94.59269  -10.26503 1.05504   1.000 74.02321  ? 288 GLU A CD  1 
ATOM   2241 O  OE1 . GLU A 1 288 ? 95.42143  -10.34407 0.12241   1.000 78.85111  ? 288 GLU A OE1 1 
ATOM   2242 O  OE2 . GLU A 1 288 ? 94.89163  -9.87327  2.20409   1.000 73.45247  ? 288 GLU A OE2 1 
ATOM   2243 N  N   . ALA A 1 289 ? 91.83881  -13.55398 -2.58139  1.000 43.18558  ? 289 ALA A N   1 
ATOM   2244 C  CA  . ALA A 1 289 ? 91.69947  -14.09687 -3.92820  1.000 43.95534  ? 289 ALA A CA  1 
ATOM   2245 C  C   . ALA A 1 289 ? 90.23931  -14.11987 -4.36029  1.000 40.00576  ? 289 ALA A C   1 
ATOM   2246 O  O   . ALA A 1 289 ? 89.92078  -13.82524 -5.51733  1.000 41.83250  ? 289 ALA A O   1 
ATOM   2247 C  CB  . ALA A 1 289 ? 92.30558  -15.49876 -3.99666  1.000 40.47482  ? 289 ALA A CB  1 
ATOM   2248 N  N   . LEU A 1 290 ? 89.33560  -14.46045 -3.44025  1.000 38.71661  ? 290 LEU A N   1 
ATOM   2249 C  CA  . LEU A 1 290 ? 87.91257  -14.44274 -3.76050  1.000 41.68996  ? 290 LEU A CA  1 
ATOM   2250 C  C   . LEU A 1 290 ? 87.42816  -13.02571 -4.03629  1.000 46.20766  ? 290 LEU A C   1 
ATOM   2251 O  O   . LEU A 1 290 ? 86.60965  -12.80773 -4.93723  1.000 41.21187  ? 290 LEU A O   1 
ATOM   2252 C  CB  . LEU A 1 290 ? 87.11232  -15.07357 -2.62124  1.000 39.80742  ? 290 LEU A CB  1 
ATOM   2253 C  CG  . LEU A 1 290 ? 85.59072  -14.93806 -2.66925  1.000 37.77523  ? 290 LEU A CG  1 
ATOM   2254 C  CD1 . LEU A 1 290 ? 85.03949  -15.55078 -3.94469  1.000 36.54265  ? 290 LEU A CD1 1 
ATOM   2255 C  CD2 . LEU A 1 290 ? 84.95729  -15.58526 -1.43575  1.000 34.49884  ? 290 LEU A CD2 1 
ATOM   2256 N  N   . GLU A 1 291 ? 87.92262  -12.04940 -3.27218  1.000 42.51103  ? 291 GLU A N   1 
ATOM   2257 C  CA  . GLU A 1 291 ? 87.53760  -10.66291 -3.51221  1.000 46.31854  ? 291 GLU A CA  1 
ATOM   2258 C  C   . GLU A 1 291 ? 88.03381  -10.18179 -4.87010  1.000 44.35398  ? 291 GLU A C   1 
ATOM   2259 O  O   . GLU A 1 291 ? 87.32159  -9.46099  -5.58021  1.000 44.00075  ? 291 GLU A O   1 
ATOM   2260 C  CB  . GLU A 1 291 ? 88.06914  -9.76835  -2.39032  1.000 50.27510  ? 291 GLU A CB  1 
ATOM   2261 C  CG  . GLU A 1 291 ? 87.86968  -8.27442  -2.62278  1.000 50.10813  ? 291 GLU A CG  1 
ATOM   2262 C  CD  . GLU A 1 291 ? 86.41447  -7.84308  -2.53533  1.000 55.86877  ? 291 GLU A CD  1 
ATOM   2263 O  OE1 . GLU A 1 291 ? 85.55358  -8.67007  -2.16014  1.000 50.91278  ? 291 GLU A OE1 1 
ATOM   2264 O  OE2 . GLU A 1 291 ? 86.13081  -6.66554  -2.84354  1.000 56.94923  ? 291 GLU A OE2 1 
ATOM   2265 N  N   . ARG A 1 292 ? 89.25203  -10.57454 -5.25154  1.000 40.33071  ? 292 ARG A N   1 
ATOM   2266 C  CA  . ARG A 1 292 ? 89.76403  -10.20141 -6.56518  1.000 40.29030  ? 292 ARG A CA  1 
ATOM   2267 C  C   . ARG A 1 292 ? 88.94770  -10.84629 -7.67656  1.000 42.65776  ? 292 ARG A C   1 
ATOM   2268 O  O   . ARG A 1 292 ? 88.69438  -10.22177 -8.71263  1.000 40.30856  ? 292 ARG A O   1 
ATOM   2269 C  CB  . ARG A 1 292 ? 91.23699  -10.58565 -6.68962  1.000 44.81925  ? 292 ARG A CB  1 
ATOM   2270 C  CG  . ARG A 1 292 ? 92.17300  -9.72971  -5.85383  1.000 40.65557  ? 292 ARG A CG  1 
ATOM   2271 C  CD  . ARG A 1 292 ? 93.50880  -9.57708  -6.54900  1.000 48.25146  ? 292 ARG A CD  1 
ATOM   2272 N  NE  . ARG A 1 292 ? 93.34727  -8.97865  -7.86833  1.000 40.81770  ? 292 ARG A NE  1 
ATOM   2273 C  CZ  . ARG A 1 292 ? 94.29619  -8.93465  -8.79207  1.000 44.55359  ? 292 ARG A CZ  1 
ATOM   2274 N  NH1 . ARG A 1 292 ? 95.49875  -9.43680  -8.57189  1.000 43.96892  ? 292 ARG A NH1 1 
ATOM   2275 N  NH2 . ARG A 1 292 ? 94.02881  -8.38101  -9.97108  1.000 43.03201  ? 292 ARG A NH2 1 
ATOM   2276 N  N   . TYR A 1 293 ? 88.52314  -12.09451 -7.47935  1.000 41.89811  ? 293 TYR A N   1 
ATOM   2277 C  CA  . TYR A 1 293 ? 87.66820  -12.74603 -8.46507  1.000 41.61770  ? 293 TYR A CA  1 
ATOM   2278 C  C   . TYR A 1 293 ? 86.35590  -11.99220 -8.62476  1.000 43.79864  ? 293 TYR A C   1 
ATOM   2279 O  O   . TYR A 1 293 ? 85.87350  -11.78594 -9.74441  1.000 37.92533  ? 293 TYR A O   1 
ATOM   2280 C  CB  . TYR A 1 293 ? 87.41038  -14.19282 -8.05035  1.000 36.04470  ? 293 TYR A CB  1 
ATOM   2281 C  CG  . TYR A 1 293 ? 86.85374  -15.07019 -9.14679  1.000 35.80626  ? 293 TYR A CG  1 
ATOM   2282 C  CD1 . TYR A 1 293 ? 87.63509  -15.42740 -10.23612 1.000 35.51315  ? 293 TYR A CD1 1 
ATOM   2283 C  CD2 . TYR A 1 293 ? 85.55875  -15.56692 -9.07813  1.000 36.52021  ? 293 TYR A CD2 1 
ATOM   2284 C  CE1 . TYR A 1 293 ? 87.14059  -16.24260 -11.23638 1.000 34.41558  ? 293 TYR A CE1 1 
ATOM   2285 C  CE2 . TYR A 1 293 ? 85.05275  -16.38590 -10.07530 1.000 31.27011  ? 293 TYR A CE2 1 
ATOM   2286 C  CZ  . TYR A 1 293 ? 85.85049  -16.71743 -11.15330 1.000 35.32287  ? 293 TYR A CZ  1 
ATOM   2287 O  OH  . TYR A 1 293 ? 85.36451  -17.53316 -12.15203 1.000 34.78377  ? 293 TYR A OH  1 
ATOM   2288 N  N   . ARG A 1 294 ? 85.76761  -11.56695 -7.50551  1.000 37.81895  ? 294 ARG A N   1 
ATOM   2289 C  CA  . ARG A 1 294 ? 84.49078  -10.86374 -7.55247  1.000 39.85732  ? 294 ARG A CA  1 
ATOM   2290 C  C   . ARG A 1 294 ? 84.60332  -9.55392  -8.32125  1.000 39.22743  ? 294 ARG A C   1 
ATOM   2291 O  O   . ARG A 1 294 ? 83.74247  -9.23601  -9.14999  1.000 38.10377  ? 294 ARG A O   1 
ATOM   2292 C  CB  . ARG A 1 294 ? 83.99004  -10.60308 -6.13008  1.000 42.91356  ? 294 ARG A CB  1 
ATOM   2293 C  CG  . ARG A 1 294 ? 82.72279  -9.76957  -6.05620  1.000 42.42917  ? 294 ARG A CG  1 
ATOM   2294 C  CD  . ARG A 1 294 ? 82.35927  -9.42653  -4.61681  1.000 45.83516  ? 294 ARG A CD  1 
ATOM   2295 N  NE  . ARG A 1 294 ? 83.22879  -8.40338  -4.04647  1.000 46.64971  ? 294 ARG A NE  1 
ATOM   2296 C  CZ  . ARG A 1 294 ? 82.99283  -7.09965  -4.11562  1.000 50.63414  ? 294 ARG A CZ  1 
ATOM   2297 N  NH1 . ARG A 1 294 ? 81.92804  -6.62213  -4.73943  1.000 49.01004  ? 294 ARG A NH1 1 
ATOM   2298 N  NH2 . ARG A 1 294 ? 83.84492  -6.25371  -3.54311  1.000 48.55326  ? 294 ARG A NH2 1 
ATOM   2299 N  N   . THR A 1 295 ? 85.65923  -8.78201  -8.06413  1.000 39.97490  ? 295 THR A N   1 
ATOM   2300 C  CA  . THR A 1 295 ? 85.75261  -7.42972  -8.60031  1.000 42.13667  ? 295 THR A CA  1 
ATOM   2301 C  C   . THR A 1 295 ? 86.45846  -7.36948  -9.95130  1.000 38.76471  ? 295 THR A C   1 
ATOM   2302 O  O   . THR A 1 295 ? 86.07625  -6.56361  -10.80504 1.000 40.02148  ? 295 THR A O   1 
ATOM   2303 C  CB  . THR A 1 295 ? 86.47322  -6.51412  -7.60422  1.000 38.89775  ? 295 THR A CB  1 
ATOM   2304 O  OG1 . THR A 1 295 ? 87.82492  -6.95600  -7.43734  1.000 44.04992  ? 295 THR A OG1 1 
ATOM   2305 C  CG2 . THR A 1 295 ? 85.77537  -6.53616  -6.25645  1.000 43.61353  ? 295 THR A CG2 1 
ATOM   2306 N  N   . ASP A 1 296 ? 87.47975  -8.19969  -10.16790 1.000 35.80586  ? 296 ASP A N   1 
ATOM   2307 C  CA  . ASP A 1 296 ? 88.28665  -8.12722  -11.37985 1.000 35.50882  ? 296 ASP A CA  1 
ATOM   2308 C  C   . ASP A 1 296 ? 87.90597  -9.16062  -12.43351 1.000 40.95281  ? 296 ASP A C   1 
ATOM   2309 O  O   . ASP A 1 296 ? 88.36176  -9.04881  -13.57700 1.000 40.92729  ? 296 ASP A O   1 
ATOM   2310 C  CB  . ASP A 1 296 ? 89.77583  -8.27939  -11.03629 1.000 37.28709  ? 296 ASP A CB  1 
ATOM   2311 C  CG  . ASP A 1 296 ? 90.32920  -7.07450  -10.29102 1.000 41.57545  ? 296 ASP A CG  1 
ATOM   2312 O  OD1 . ASP A 1 296 ? 89.61226  -6.05604  -10.19193 1.000 41.28824  ? 296 ASP A OD1 1 
ATOM   2313 O  OD2 . ASP A 1 296 ? 91.48031  -7.14301  -9.80705  1.000 42.13987  ? 296 ASP A OD2 1 
ATOM   2314 N  N   . ALA A 1 297 ? 87.08655  -10.15221 -12.09339 1.000 38.24899  ? 297 ALA A N   1 
ATOM   2315 C  CA  . ALA A 1 297 ? 86.71286  -11.18421 -13.05230 1.000 34.90614  ? 297 ALA A CA  1 
ATOM   2316 C  C   . ALA A 1 297 ? 85.21735  -11.22478 -13.31970 1.000 37.04477  ? 297 ALA A C   1 
ATOM   2317 O  O   . ALA A 1 297 ? 84.79964  -11.15619 -14.48174 1.000 38.24796  ? 297 ALA A O   1 
ATOM   2318 C  CB  . ALA A 1 297 ? 87.20760  -12.55945 -12.56991 1.000 35.65668  ? 297 ALA A CB  1 
ATOM   2319 N  N   . VAL A 1 298 ? 84.39026  -11.31974 -12.27986 1.000 37.55555  ? 298 VAL A N   1 
ATOM   2320 C  CA  . VAL A 1 298 ? 82.95369  -11.45828 -12.49608 1.000 35.49618  ? 298 VAL A CA  1 
ATOM   2321 C  C   . VAL A 1 298 ? 82.31445  -10.10399 -12.77368 1.000 41.88486  ? 298 VAL A C   1 
ATOM   2322 O  O   . VAL A 1 298 ? 81.53008  -9.95478  -13.71845 1.000 35.92044  ? 298 VAL A O   1 
ATOM   2323 C  CB  . VAL A 1 298 ? 82.29674  -12.16206 -11.29519 1.000 42.01243  ? 298 VAL A CB  1 
ATOM   2324 C  CG1 . VAL A 1 298 ? 80.79385  -12.29607 -11.51095 1.000 35.97060  ? 298 VAL A CG1 1 
ATOM   2325 C  CG2 . VAL A 1 298 ? 82.93600  -13.52669 -11.07238 1.000 43.04290  ? 298 VAL A CG2 1 
ATOM   2326 N  N   . ARG A 1 299 ? 82.63687  -9.09758  -11.95655 1.000 40.23471  ? 299 ARG A N   1 
ATOM   2327 C  CA  . ARG A 1 299 ? 82.05964  -7.77293  -12.16140 1.000 44.76201  ? 299 ARG A CA  1 
ATOM   2328 C  C   . ARG A 1 299 ? 82.49576  -7.18005  -13.49381 1.000 44.56518  ? 299 ARG A C   1 
ATOM   2329 O  O   . ARG A 1 299 ? 81.69960  -6.53283  -14.18525 1.000 38.13126  ? 299 ARG A O   1 
ATOM   2330 C  CB  . ARG A 1 299 ? 82.44673  -6.84509  -11.01099 1.000 40.55620  ? 299 ARG A CB  1 
ATOM   2331 C  CG  . ARG A 1 299 ? 81.36463  -6.70891  -9.95083  1.000 41.20089  ? 299 ARG A CG  1 
ATOM   2332 C  CD  . ARG A 1 299 ? 81.84545  -5.93275  -8.73255  1.000 39.91121  ? 299 ARG A CD  1 
ATOM   2333 N  NE  . ARG A 1 299 ? 80.77057  -5.75474  -7.76269  1.000 48.00487  ? 299 ARG A NE  1 
ATOM   2334 C  CZ  . ARG A 1 299 ? 80.36852  -4.58412  -7.28469  1.000 45.80736  ? 299 ARG A CZ  1 
ATOM   2335 N  NH1 . ARG A 1 299 ? 80.97666  -3.45495  -7.61292  1.000 46.35891  ? 299 ARG A NH1 1 
ATOM   2336 N  NH2 . ARG A 1 299 ? 79.33087  -4.54548  -6.45393  1.000 44.61322  ? 299 ARG A NH2 1 
ATOM   2337 N  N   . THR A 1 300 ? 83.75541  -7.39919  -13.87603 1.000 38.65539  ? 300 THR A N   1 
ATOM   2338 C  CA  . THR A 1 300 ? 84.26538  -6.80072  -15.10457 1.000 37.91517  ? 300 THR A CA  1 
ATOM   2339 C  C   . THR A 1 300 ? 83.59868  -7.39681  -16.33879 1.000 41.88201  ? 300 THR A C   1 
ATOM   2340 O  O   . THR A 1 300 ? 83.30277  -6.67382  -17.29702 1.000 41.09866  ? 300 THR A O   1 
ATOM   2341 C  CB  . THR A 1 300 ? 85.78129  -6.96872  -15.18215 1.000 40.31923  ? 300 THR A CB  1 
ATOM   2342 O  OG1 . THR A 1 300 ? 86.12942  -8.31813  -14.84644 1.000 38.84421  ? 300 THR A OG1 1 
ATOM   2343 C  CG2 . THR A 1 300 ? 86.46761  -6.01642  -14.21380 1.000 41.15646  ? 300 THR A CG2 1 
ATOM   2344 N  N   . VAL A 1 301 ? 83.34920  -8.71104  -16.33794 1.000 37.67457  ? 301 VAL A N   1 
ATOM   2345 C  CA  . VAL A 1 301 ? 82.74441  -9.33130  -17.51489 1.000 39.85273  ? 301 VAL A CA  1 
ATOM   2346 C  C   . VAL A 1 301 ? 81.29885  -8.87808  -17.67826 1.000 39.19093  ? 301 VAL A C   1 
ATOM   2347 O  O   . VAL A 1 301 ? 80.77418  -8.85568  -18.79640 1.000 43.15624  ? 301 VAL A O   1 
ATOM   2348 C  CB  . VAL A 1 301 ? 82.85730  -10.86997 -17.45510 1.000 38.57065  ? 301 VAL A CB  1 
ATOM   2349 C  CG1 . VAL A 1 301 ? 81.72284  -11.47492 -16.65334 1.000 40.07101  ? 301 VAL A CG1 1 
ATOM   2350 C  CG2 . VAL A 1 301 ? 82.87539  -11.45900 -18.86150 1.000 41.30625  ? 301 VAL A CG2 1 
ATOM   2351 N  N   . ILE A 1 302 ? 80.63624  -8.49574  -16.58583 1.000 45.78692  ? 302 ILE A N   1 
ATOM   2352 C  CA  . ILE A 1 302 ? 79.28201  -7.96050  -16.68643 1.000 44.93976  ? 302 ILE A CA  1 
ATOM   2353 C  C   . ILE A 1 302 ? 79.31052  -6.52718  -17.19892 1.000 47.77228  ? 302 ILE A C   1 
ATOM   2354 O  O   . ILE A 1 302 ? 78.64215  -6.18488  -18.18033 1.000 50.46524  ? 302 ILE A O   1 
ATOM   2355 C  CB  . ILE A 1 302 ? 78.56724  -8.05009  -15.32591 1.000 46.24991  ? 302 ILE A CB  1 
ATOM   2356 C  CG1 . ILE A 1 302 ? 78.45549  -9.50569  -14.87109 1.000 49.38636  ? 302 ILE A CG1 1 
ATOM   2357 C  CG2 . ILE A 1 302 ? 77.19426  -7.40736  -15.40851 1.000 50.33404  ? 302 ILE A CG2 1 
ATOM   2358 C  CD1 . ILE A 1 302 ? 77.87409  -9.66289  -13.48342 1.000 49.54978  ? 302 ILE A CD1 1 
ATOM   2359 N  N   . ARG A 1 303 ? 80.09650  -5.67167  -16.54589 1.000 43.24380  ? 303 ARG A N   1 
ATOM   2360 C  CA  . ARG A 1 303 ? 80.08493  -4.24895  -16.86668 1.000 42.48248  ? 303 ARG A CA  1 
ATOM   2361 C  C   . ARG A 1 303 ? 80.82436  -3.95365  -18.16731 1.000 45.16085  ? 303 ARG A C   1 
ATOM   2362 O  O   . ARG A 1 303 ? 80.36111  -3.14301  -18.97690 1.000 42.83425  ? 303 ARG A O   1 
ATOM   2363 C  CB  . ARG A 1 303 ? 80.69443  -3.45460  -15.71284 1.000 42.01687  ? 303 ARG A CB  1 
ATOM   2364 C  CG  . ARG A 1 303 ? 80.87525  -1.98167  -16.01454 1.000 50.50732  ? 303 ARG A CG  1 
ATOM   2365 C  CD  . ARG A 1 303 ? 79.54010  -1.25362  -16.07235 1.000 50.70020  ? 303 ARG A CD  1 
ATOM   2366 N  NE  . ARG A 1 303 ? 79.65885  0.02162   -16.76850 1.000 56.42452  ? 303 ARG A NE  1 
ATOM   2367 C  CZ  . ARG A 1 303 ? 78.78525  1.01384   -16.67300 1.000 56.71058  ? 303 ARG A CZ  1 
ATOM   2368 N  NH1 . ARG A 1 303 ? 77.73172  0.93296   -15.87716 1.000 61.47582  ? 303 ARG A NH1 1 
ATOM   2369 N  NH2 . ARG A 1 303 ? 78.97404  2.11559   -17.39379 1.000 56.64954  ? 303 ARG A NH2 1 
ATOM   2370 N  N   . GLY A 1 304 ? 81.98281  -4.58141  -18.37704 1.000 40.74246  ? 304 GLY A N   1 
ATOM   2371 C  CA  . GLY A 1 304 ? 82.74623  -4.32069  -19.58527 1.000 40.82639  ? 304 GLY A CA  1 
ATOM   2372 C  C   . GLY A 1 304 ? 81.99405  -4.68247  -20.85002 1.000 46.16788  ? 304 GLY A C   1 
ATOM   2373 O  O   . GLY A 1 304 ? 82.15882  -4.03299  -21.88595 1.000 45.27069  ? 304 GLY A O   1 
ATOM   2374 N  N   . SER A 1 305 ? 81.15363  -5.71399  -20.78429 1.000 46.78253  ? 305 SER A N   1 
ATOM   2375 C  CA  . SER A 1 305 ? 80.36992  -6.10121  -21.95069 1.000 50.12466  ? 305 SER A CA  1 
ATOM   2376 C  C   . SER A 1 305 ? 79.30644  -5.05873  -22.27047 1.000 56.84929  ? 305 SER A C   1 
ATOM   2377 O  O   . SER A 1 305 ? 79.00549  -4.80945  -23.44481 1.000 54.79274  ? 305 SER A O   1 
ATOM   2378 C  CB  . SER A 1 305 ? 79.73080  -7.46636  -21.71201 1.000 48.87558  ? 305 SER A CB  1 
ATOM   2379 O  OG  . SER A 1 305 ? 79.05222  -7.92474  -22.86504 1.000 56.48472  ? 305 SER A OG  1 
ATOM   2380 N  N   . TYR A 1 306 ? 78.72785  -4.44027  -21.23766 1.000 51.29143  ? 306 TYR A N   1 
ATOM   2381 C  CA  . TYR A 1 306 ? 77.69351  -3.43438  -21.45544 1.000 53.40530  ? 306 TYR A CA  1 
ATOM   2382 C  C   . TYR A 1 306 ? 78.24654  -2.23366  -22.21310 1.000 56.73740  ? 306 TYR A C   1 
ATOM   2383 O  O   . TYR A 1 306 ? 77.62296  -1.73935  -23.15803 1.000 55.48424  ? 306 TYR A O   1 
ATOM   2384 C  CB  . TYR A 1 306 ? 77.09941  -3.00589  -20.11448 1.000 52.86185  ? 306 TYR A CB  1 
ATOM   2385 C  CG  . TYR A 1 306 ? 76.13257  -1.84637  -20.19727 1.000 59.43631  ? 306 TYR A CG  1 
ATOM   2386 C  CD1 . TYR A 1 306 ? 74.84438  -2.02401  -20.68277 1.000 63.41877  ? 306 TYR A CD1 1 
ATOM   2387 C  CD2 . TYR A 1 306 ? 76.50235  -0.57717  -19.77030 1.000 63.39418  ? 306 TYR A CD2 1 
ATOM   2388 C  CE1 . TYR A 1 306 ? 73.95404  -0.96881  -20.75258 1.000 68.14197  ? 306 TYR A CE1 1 
ATOM   2389 C  CE2 . TYR A 1 306 ? 75.61858  0.48542   -19.83488 1.000 66.20314  ? 306 TYR A CE2 1 
ATOM   2390 C  CZ  . TYR A 1 306 ? 74.34547  0.28314   -20.32665 1.000 72.07371  ? 306 TYR A CZ  1 
ATOM   2391 O  OH  . TYR A 1 306 ? 73.45951  1.33359   -20.39505 1.000 81.01503  ? 306 TYR A OH  1 
ATOM   2392 N  N   . ASP A 1 307 ? 79.42671  -1.75566  -21.81676 1.000 54.11185  ? 307 ASP A N   1 
ATOM   2393 C  CA  . ASP A 1 307 ? 80.01514  -0.59835  -22.48373 1.000 55.75408  ? 307 ASP A CA  1 
ATOM   2394 C  C   . ASP A 1 307 ? 80.38699  -0.91422  -23.92817 1.000 58.97092  ? 307 ASP A C   1 
ATOM   2395 O  O   . ASP A 1 307 ? 80.17675  -0.08942  -24.82523 1.000 68.82207  ? 307 ASP A O   1 
ATOM   2396 C  CB  . ASP A 1 307 ? 81.24359  -0.11804  -21.71037 1.000 53.84228  ? 307 ASP A CB  1 
ATOM   2397 C  CG  . ASP A 1 307 ? 80.91432  0.29029   -20.28630 1.000 61.31925  ? 307 ASP A CG  1 
ATOM   2398 O  OD1 . ASP A 1 307 ? 79.77774  0.75163   -20.04409 1.000 66.46281  ? 307 ASP A OD1 1 
ATOM   2399 O  OD2 . ASP A 1 307 ? 81.79293  0.15372   -19.40756 1.000 57.69597  ? 307 ASP A OD2 1 
ATOM   2400 N  N   . TRP A 1 308 ? 80.93477  -2.10693  -24.17497 1.000 58.30515  ? 308 TRP A N   1 
ATOM   2401 C  CA  . TRP A 1 308 ? 81.45606  -2.43576  -25.49886 1.000 54.95340  ? 308 TRP A CA  1 
ATOM   2402 C  C   . TRP A 1 308 ? 80.35670  -2.74509  -26.50859 1.000 58.38440  ? 308 TRP A C   1 
ATOM   2403 O  O   . TRP A 1 308 ? 80.50929  -2.42922  -27.69415 1.000 61.31347  ? 308 TRP A O   1 
ATOM   2404 C  CB  . TRP A 1 308 ? 82.41758  -3.61832  -25.39767 1.000 53.83602  ? 308 TRP A CB  1 
ATOM   2405 C  CG  . TRP A 1 308 ? 82.92995  -4.11954  -26.71465 1.000 51.00828  ? 308 TRP A CG  1 
ATOM   2406 C  CD1 . TRP A 1 308 ? 83.98887  -3.62841  -27.42049 1.000 45.92939  ? 308 TRP A CD1 1 
ATOM   2407 C  CD2 . TRP A 1 308 ? 82.42015  -5.22513  -27.47306 1.000 47.06798  ? 308 TRP A CD2 1 
ATOM   2408 N  NE1 . TRP A 1 308 ? 84.16828  -4.35422  -28.57356 1.000 46.94908  ? 308 TRP A NE1 1 
ATOM   2409 C  CE2 . TRP A 1 308 ? 83.21845  -5.34062  -28.62954 1.000 43.79901  ? 308 TRP A CE2 1 
ATOM   2410 C  CE3 . TRP A 1 308 ? 81.36489  -6.12654  -27.28808 1.000 46.93086  ? 308 TRP A CE3 1 
ATOM   2411 C  CZ2 . TRP A 1 308 ? 82.99425  -6.32012  -29.59766 1.000 37.96607  ? 308 TRP A CZ2 1 
ATOM   2412 C  CZ3 . TRP A 1 308 ? 81.14466  -7.09891  -28.24934 1.000 48.53712  ? 308 TRP A CZ3 1 
ATOM   2413 C  CH2 . TRP A 1 308 ? 81.95548  -7.18691  -29.39044 1.000 47.15619  ? 308 TRP A CH2 1 
ATOM   2414 N  N   . HIS A 1 309 ? 79.25480  -3.36245  -26.07475 1.000 59.21238  ? 309 HIS A N   1 
ATOM   2415 C  CA  . HIS A 1 309 ? 78.17041  -3.66504  -27.00331 1.000 57.43806  ? 309 HIS A CA  1 
ATOM   2416 C  C   . HIS A 1 309 ? 77.52537  -2.40896  -27.57205 1.000 62.26343  ? 309 HIS A C   1 
ATOM   2417 O  O   . HIS A 1 309 ? 76.86847  -2.48364  -28.61577 1.000 63.69065  ? 309 HIS A O   1 
ATOM   2418 C  CB  . HIS A 1 309 ? 77.10538  -4.52868  -26.32421 1.000 51.75511  ? 309 HIS A CB  1 
ATOM   2419 C  CG  . HIS A 1 309 ? 77.35934  -5.99843  -26.43880 1.000 57.07063  ? 309 HIS A CG  1 
ATOM   2420 N  ND1 . HIS A 1 309 ? 77.92962  -6.73780  -25.42493 1.000 58.57400  ? 309 HIS A ND1 1 
ATOM   2421 C  CD2 . HIS A 1 309 ? 77.12963  -6.86532  -27.45335 1.000 56.27689  ? 309 HIS A CD2 1 
ATOM   2422 C  CE1 . HIS A 1 309 ? 78.03510  -7.99779  -25.80811 1.000 57.79288  ? 309 HIS A CE1 1 
ATOM   2423 N  NE2 . HIS A 1 309 ? 77.55753  -8.10187  -27.03537 1.000 59.25400  ? 309 HIS A NE2 1 
ATOM   2424 N  N   . ARG A 1 310 ? 77.69829  -1.25915  -26.91731 1.000 65.91972  ? 310 ARG A N   1 
ATOM   2425 C  CA  . ARG A 1 310 ? 77.13886  -0.01854  -27.44091 1.000 72.15387  ? 310 ARG A CA  1 
ATOM   2426 C  C   . ARG A 1 310 ? 78.05943  0.64736   -28.45529 1.000 68.00880  ? 310 ARG A C   1 
ATOM   2427 O  O   . ARG A 1 310 ? 77.57532  1.28887   -29.39403 1.000 78.26590  ? 310 ARG A O   1 
ATOM   2428 C  CB  . ARG A 1 310 ? 76.84533  0.95221   -26.29708 1.000 71.45905  ? 310 ARG A CB  1 
ATOM   2429 C  CG  . ARG A 1 310 ? 76.24239  0.28962   -25.07326 1.000 71.53301  ? 310 ARG A CG  1 
ATOM   2430 C  CD  . ARG A 1 310 ? 75.87895  1.30035   -23.99527 1.000 71.99041  ? 310 ARG A CD  1 
ATOM   2431 N  NE  . ARG A 1 310 ? 74.52743  1.81656   -24.17385 1.000 83.51721  ? 310 ARG A NE  1 
ATOM   2432 C  CZ  . ARG A 1 310 ? 73.96019  2.72236   -23.38922 1.000 84.71483  ? 310 ARG A CZ  1 
ATOM   2433 N  NH1 . ARG A 1 310 ? 74.60957  3.25621   -22.36772 1.000 82.25454  ? 310 ARG A NH1 1 
ATOM   2434 N  NH2 . ARG A 1 310 ? 72.70959  3.10182   -23.63565 1.000 91.96563  ? 310 ARG A NH2 1 
ATOM   2435 N  N   . SER A 1 311 ? 79.37553  0.50228   -28.29502 1.000 66.47411  ? 311 SER A N   1 
ATOM   2436 C  CA  . SER A 1 311 ? 80.33700  1.23997   -29.10545 1.000 64.54960  ? 311 SER A CA  1 
ATOM   2437 C  C   . SER A 1 311 ? 80.99915  0.40915   -30.19655 1.000 63.31002  ? 311 SER A C   1 
ATOM   2438 O  O   . SER A 1 311 ? 81.56355  0.99103   -31.13011 1.000 69.26836  ? 311 SER A O   1 
ATOM   2439 C  CB  . SER A 1 311 ? 81.43383  1.83723   -28.21422 1.000 68.66685  ? 311 SER A CB  1 
ATOM   2440 O  OG  . SER A 1 311 ? 82.14218  0.82104   -27.52601 1.000 68.31740  ? 311 SER A OG  1 
ATOM   2441 N  N   . SER A 1 312 ? 80.95183  -0.91914  -30.10773 1.000 62.36794  ? 312 SER A N   1 
ATOM   2442 C  CA  . SER A 1 312 ? 81.66694  -1.75423  -31.06451 1.000 59.95368  ? 312 SER A CA  1 
ATOM   2443 C  C   . SER A 1 312 ? 81.13397  -1.54968  -32.47847 1.000 57.06284  ? 312 SER A C   1 
ATOM   2444 O  O   . SER A 1 312 ? 79.95085  -1.26614  -32.68946 1.000 54.76633  ? 312 SER A O   1 
ATOM   2445 C  CB  . SER A 1 312 ? 81.55372  -3.22890  -30.67857 1.000 52.64976  ? 312 SER A CB  1 
ATOM   2446 O  OG  . SER A 1 312 ? 82.13546  -4.05981  -31.66972 1.000 54.59302  ? 312 SER A OG  1 
ATOM   2447 N  N   . GLY A 1 313 ? 82.03128  -1.70118  -33.45623 1.000 53.03332  ? 313 GLY A N   1 
ATOM   2448 C  CA  . GLY A 1 313 ? 81.64196  -1.59973  -34.85186 1.000 51.00637  ? 313 GLY A CA  1 
ATOM   2449 C  C   . GLY A 1 313 ? 80.90494  -2.81340  -35.37706 1.000 63.34517  ? 313 GLY A C   1 
ATOM   2450 O  O   . GLY A 1 313 ? 80.29778  -2.73770  -36.45023 1.000 65.46618  ? 313 GLY A O   1 
ATOM   2451 N  N   . ARG A 1 314 ? 80.93769  -3.92993  -34.64209 1.000 56.40052  ? 314 ARG A N   1 
ATOM   2452 C  CA  . ARG A 1 314 ? 80.21953  -5.12914  -35.06009 1.000 56.94180  ? 314 ARG A CA  1 
ATOM   2453 C  C   . ARG A 1 314 ? 78.71162  -4.93335  -35.04966 1.000 57.40714  ? 314 ARG A C   1 
ATOM   2454 O  O   . ARG A 1 314 ? 77.99400  -5.71471  -35.68264 1.000 59.74660  ? 314 ARG A O   1 
ATOM   2455 C  CB  . ARG A 1 314 ? 80.57648  -6.31401  -34.15703 1.000 59.11720  ? 314 ARG A CB  1 
ATOM   2456 C  CG  . ARG A 1 314 ? 82.03110  -6.73004  -34.21019 1.000 54.31728  ? 314 ARG A CG  1 
ATOM   2457 C  CD  . ARG A 1 314 ? 82.28215  -7.95144  -33.34264 1.000 58.59357  ? 314 ARG A CD  1 
ATOM   2458 N  NE  . ARG A 1 314 ? 82.58784  -9.13062  -34.14342 1.000 62.06432  ? 314 ARG A NE  1 
ATOM   2459 C  CZ  . ARG A 1 314 ? 81.72588  -10.10713 -34.38435 1.000 58.33931  ? 314 ARG A CZ  1 
ATOM   2460 N  NH1 . ARG A 1 314 ? 80.49775  -10.07496 -33.89912 1.000 65.35506  ? 314 ARG A NH1 1 
ATOM   2461 N  NH2 . ARG A 1 314 ? 82.10881  -11.14566 -35.12151 1.000 57.67407  ? 314 ARG A NH2 1 
ATOM   2462 N  N   . TYR A 1 315 ? 78.21529  -3.91679  -34.34309 1.000 55.01097  ? 315 TYR A N   1 
ATOM   2463 C  CA  . TYR A 1 315 ? 76.78169  -3.70091  -34.18793 1.000 59.78273  ? 315 TYR A CA  1 
ATOM   2464 C  C   . TYR A 1 315 ? 76.36172  -2.30205  -34.62820 1.000 59.47580  ? 315 TYR A C   1 
ATOM   2465 O  O   . TYR A 1 315 ? 75.26517  -1.84755  -34.28482 1.000 64.63920  ? 315 TYR A O   1 
ATOM   2466 C  CB  . TYR A 1 315 ? 76.37271  -3.96721  -32.73838 1.000 59.22648  ? 315 TYR A CB  1 
ATOM   2467 C  CG  . TYR A 1 315 ? 77.06248  -5.18622  -32.16747 1.000 62.44568  ? 315 TYR A CG  1 
ATOM   2468 C  CD1 . TYR A 1 315 ? 76.72215  -6.46330  -32.59629 1.000 56.01513  ? 315 TYR A CD1 1 
ATOM   2469 C  CD2 . TYR A 1 315 ? 78.06899  -5.06052  -31.21799 1.000 51.81931  ? 315 TYR A CD2 1 
ATOM   2470 C  CE1 . TYR A 1 315 ? 77.35710  -7.58107  -32.08872 1.000 60.85288  ? 315 TYR A CE1 1 
ATOM   2471 C  CE2 . TYR A 1 315 ? 78.70879  -6.17321  -30.70307 1.000 55.01511  ? 315 TYR A CE2 1 
ATOM   2472 C  CZ  . TYR A 1 315 ? 78.34886  -7.43075  -31.14096 1.000 60.58249  ? 315 TYR A CZ  1 
ATOM   2473 O  OH  . TYR A 1 315 ? 78.98432  -8.53996  -30.63341 1.000 55.27950  ? 315 TYR A OH  1 
ATOM   2474 N  N   . ASP A 1 316 ? 77.21109  -1.61413  -35.38582 1.000 63.17645  ? 316 ASP A N   1 
ATOM   2475 C  CA  . ASP A 1 316 ? 76.88754  -0.29164  -35.91228 1.000 72.10455  ? 316 ASP A CA  1 
ATOM   2476 C  C   . ASP A 1 316 ? 76.11931  -0.41323  -37.22255 1.000 67.01047  ? 316 ASP A C   1 
ATOM   2477 O  O   . ASP A 1 316 ? 76.40410  -1.29203  -38.03429 1.000 68.11739  ? 316 ASP A O   1 
ATOM   2478 C  CB  . ASP A 1 316 ? 78.16020  0.53314   -36.12075 1.000 64.87618  ? 316 ASP A CB  1 
ATOM   2479 N  N   . ALA A 1 325 ? 81.68817  -9.07064  -48.91800 1.000 72.50047  ? 325 ALA A N   1 
ATOM   2480 C  CA  . ALA A 1 325 ? 83.03383  -9.55269  -48.62567 1.000 70.69564  ? 325 ALA A CA  1 
ATOM   2481 C  C   . ALA A 1 325 ? 82.98908  -10.83501 -47.80208 1.000 66.37721  ? 325 ALA A C   1 
ATOM   2482 O  O   . ALA A 1 325 ? 83.99649  -11.24168 -47.22193 1.000 67.26345  ? 325 ALA A O   1 
ATOM   2483 C  CB  . ALA A 1 325 ? 83.83698  -8.48298  -47.89783 1.000 62.99319  ? 325 ALA A CB  1 
ATOM   2484 N  N   . GLN A 1 326 ? 81.81358  -11.46282 -47.75545 1.000 64.06071  ? 326 GLN A N   1 
ATOM   2485 C  CA  . GLN A 1 326 ? 81.65191  -12.71168 -47.02310 1.000 58.85300  ? 326 GLN A CA  1 
ATOM   2486 C  C   . GLN A 1 326 ? 82.61860  -13.76761 -47.54542 1.000 63.39221  ? 326 GLN A C   1 
ATOM   2487 O  O   . GLN A 1 326 ? 82.89208  -13.84563 -48.74621 1.000 53.28402  ? 326 GLN A O   1 
ATOM   2488 C  CB  . GLN A 1 326 ? 80.20969  -13.21092 -47.14091 1.000 57.77382  ? 326 GLN A CB  1 
ATOM   2489 N  N   . GLY A 1 327 ? 83.15307  -14.56950 -46.62635 1.000 65.44965  ? 327 GLY A N   1 
ATOM   2490 C  CA  . GLY A 1 327 ? 84.08681  -15.62039 -46.96711 1.000 56.95048  ? 327 GLY A CA  1 
ATOM   2491 C  C   . GLY A 1 327 ? 85.54231  -15.20996 -47.03040 1.000 60.85611  ? 327 GLY A C   1 
ATOM   2492 O  O   . GLY A 1 327 ? 86.39177  -16.06064 -47.32547 1.000 56.77901  ? 327 GLY A O   1 
ATOM   2493 N  N   . TYR A 1 328 ? 85.86564  -13.94238 -46.75273 1.000 58.27047  ? 328 TYR A N   1 
ATOM   2494 C  CA  . TYR A 1 328 ? 87.24768  -13.48837 -46.87388 1.000 56.33490  ? 328 TYR A CA  1 
ATOM   2495 C  C   . TYR A 1 328 ? 88.16105  -14.11024 -45.82190 1.000 55.53969  ? 328 TYR A C   1 
ATOM   2496 O  O   . TYR A 1 328 ? 89.38299  -14.11075 -46.00550 1.000 56.09710  ? 328 TYR A O   1 
ATOM   2497 C  CB  . TYR A 1 328 ? 87.31233  -11.95655 -46.80198 1.000 59.01325  ? 328 TYR A CB  1 
ATOM   2498 C  CG  . TYR A 1 328 ? 87.20536  -11.37213 -45.40533 1.000 56.77211  ? 328 TYR A CG  1 
ATOM   2499 C  CD1 . TYR A 1 328 ? 85.97114  -11.21276 -44.78504 1.000 57.09527  ? 328 TYR A CD1 1 
ATOM   2500 C  CD2 . TYR A 1 328 ? 88.33992  -10.96150 -44.71446 1.000 55.94134  ? 328 TYR A CD2 1 
ATOM   2501 C  CE1 . TYR A 1 328 ? 85.87187  -10.67423 -43.50664 1.000 64.51323  ? 328 TYR A CE1 1 
ATOM   2502 C  CE2 . TYR A 1 328 ? 88.24983  -10.41899 -43.43874 1.000 58.58821  ? 328 TYR A CE2 1 
ATOM   2503 C  CZ  . TYR A 1 328 ? 87.01567  -10.28020 -42.83892 1.000 62.50805  ? 328 TYR A CZ  1 
ATOM   2504 O  OH  . TYR A 1 328 ? 86.92862  -9.74530  -41.57023 1.000 58.70099  ? 328 TYR A OH  1 
ATOM   2505 N  N   . LEU A 1 329 ? 87.60269  -14.64896 -44.73822 1.000 56.88502  ? 329 LEU A N   1 
ATOM   2506 C  CA  . LEU A 1 329 ? 88.37884  -15.31055 -43.69607 1.000 60.22103  ? 329 LEU A CA  1 
ATOM   2507 C  C   . LEU A 1 329 ? 88.42188  -16.82694 -43.85538 1.000 64.00956  ? 329 LEU A C   1 
ATOM   2508 O  O   . LEU A 1 329 ? 88.88758  -17.51663 -42.94195 1.000 55.99828  ? 329 LEU A O   1 
ATOM   2509 C  CB  . LEU A 1 329 ? 87.81466  -14.96256 -42.31446 1.000 53.68910  ? 329 LEU A CB  1 
ATOM   2510 C  CG  . LEU A 1 329 ? 87.98853  -13.52278 -41.82923 1.000 60.40689  ? 329 LEU A CG  1 
ATOM   2511 C  CD1 . LEU A 1 329 ? 87.22289  -13.30051 -40.53085 1.000 48.65019  ? 329 LEU A CD1 1 
ATOM   2512 C  CD2 . LEU A 1 329 ? 89.46702  -13.18303 -41.65880 1.000 54.55641  ? 329 LEU A CD2 1 
ATOM   2513 N  N   . GLU A 1 330 ? 87.96244  -17.35607 -44.99387 1.000 63.56648  ? 330 GLU A N   1 
ATOM   2514 C  CA  . GLU A 1 330 ? 87.81593  -18.80259 -45.14173 1.000 62.64305  ? 330 GLU A CA  1 
ATOM   2515 C  C   . GLU A 1 330 ? 89.14892  -19.52654 -45.00033 1.000 62.99301  ? 330 GLU A C   1 
ATOM   2516 O  O   . GLU A 1 330 ? 89.20596  -20.62877 -44.44208 1.000 60.00192  ? 330 GLU A O   1 
ATOM   2517 C  CB  . GLU A 1 330 ? 87.17422  -19.13265 -46.48890 1.000 62.73785  ? 330 GLU A CB  1 
ATOM   2518 C  CG  . GLU A 1 330 ? 85.74620  -19.61783 -46.37258 1.000 62.83641  ? 330 GLU A CG  1 
ATOM   2519 C  CD  . GLU A 1 330 ? 85.60134  -20.75995 -45.38071 1.000 72.37447  ? 330 GLU A CD  1 
ATOM   2520 O  OE1 . GLU A 1 330 ? 86.31471  -21.77790 -45.52699 1.000 74.11475  ? 330 GLU A OE1 1 
ATOM   2521 O  OE2 . GLU A 1 330 ? 84.77845  -20.63544 -44.44782 1.000 66.99078  ? 330 GLU A OE2 1 
ATOM   2522 N  N   . GLU A 1 331 ? 90.23265  -18.92564 -45.49604 1.000 54.99233  ? 331 GLU A N   1 
ATOM   2523 C  CA  . GLU A 1 331 ? 91.53986  -19.56837 -45.42723 1.000 57.59884  ? 331 GLU A CA  1 
ATOM   2524 C  C   . GLU A 1 331 ? 92.04163  -19.75008 -43.99697 1.000 59.20065  ? 331 GLU A C   1 
ATOM   2525 O  O   . GLU A 1 331 ? 93.00201  -20.50067 -43.78968 1.000 54.06419  ? 331 GLU A O   1 
ATOM   2526 C  CB  . GLU A 1 331 ? 92.55143  -18.76285 -46.24206 1.000 57.29575  ? 331 GLU A CB  1 
ATOM   2527 C  CG  . GLU A 1 331 ? 92.68038  -17.31630 -45.80089 1.000 62.64879  ? 331 GLU A CG  1 
ATOM   2528 C  CD  . GLU A 1 331 ? 93.31056  -16.44285 -46.86568 1.000 64.41733  ? 331 GLU A CD  1 
ATOM   2529 O  OE1 . GLU A 1 331 ? 93.85732  -16.99769 -47.84358 1.000 60.51475  ? 331 GLU A OE1 1 
ATOM   2530 O  OE2 . GLU A 1 331 ? 93.25363  -15.20170 -46.72811 1.000 59.24873  ? 331 GLU A OE2 1 
ATOM   2531 N  N   . LEU A 1 332 ? 91.42564  -19.08973 -43.01029 1.000 47.64355  ? 332 LEU A N   1 
ATOM   2532 C  CA  . LEU A 1 332 ? 91.80622  -19.30971 -41.61737 1.000 62.24904  ? 332 LEU A CA  1 
ATOM   2533 C  C   . LEU A 1 332 ? 91.41249  -20.69616 -41.12488 1.000 53.97782  ? 332 LEU A C   1 
ATOM   2534 O  O   . LEU A 1 332 ? 92.03676  -21.21000 -40.18992 1.000 45.91585  ? 332 LEU A O   1 
ATOM   2535 C  CB  . LEU A 1 332 ? 91.17148  -18.25421 -40.70514 1.000 46.33965  ? 332 LEU A CB  1 
ATOM   2536 C  CG  . LEU A 1 332 ? 91.53504  -16.78121 -40.90815 1.000 55.72593  ? 332 LEU A CG  1 
ATOM   2537 C  CD1 . LEU A 1 332 ? 91.30374  -16.02569 -39.60157 1.000 46.05031  ? 332 LEU A CD1 1 
ATOM   2538 C  CD2 . LEU A 1 332 ? 92.96460  -16.61239 -41.41568 1.000 49.36670  ? 332 LEU A CD2 1 
ATOM   2539 N  N   . GLY A 1 333 ? 90.39153  -21.30411 -41.72229 1.000 53.20766  ? 333 GLY A N   1 
ATOM   2540 C  CA  . GLY A 1 333 ? 89.93686  -22.62365 -41.34565 1.000 50.93044  ? 333 GLY A CA  1 
ATOM   2541 C  C   . GLY A 1 333 ? 90.35933  -23.73712 -42.27658 1.000 55.45358  ? 333 GLY A C   1 
ATOM   2542 O  O   . GLY A 1 333 ? 89.81757  -24.84396 -42.17514 1.000 54.59644  ? 333 GLY A O   1 
ATOM   2543 N  N   . SER A 1 334 ? 91.30937  -23.49010 -43.17376 1.000 55.47784  ? 334 SER A N   1 
ATOM   2544 C  CA  . SER A 1 334 ? 91.75091  -24.47289 -44.15595 1.000 64.37000  ? 334 SER A CA  1 
ATOM   2545 C  C   . SER A 1 334 ? 93.10266  -25.03479 -43.73398 1.000 62.03665  ? 334 SER A C   1 
ATOM   2546 O  O   . SER A 1 334 ? 94.05452  -24.27858 -43.50517 1.000 61.63091  ? 334 SER A O   1 
ATOM   2547 C  CB  . SER A 1 334 ? 91.83456  -23.85474 -45.55254 1.000 59.03711  ? 334 SER A CB  1 
ATOM   2548 O  OG  . SER A 1 334 ? 90.54841  -23.51062 -46.03716 1.000 68.97313  ? 334 SER A OG  1 
ATOM   2549 N  N   . SER A 1 335 ? 93.18186  -26.35691 -43.63772 1.000 63.18271  ? 335 SER A N   1 
ATOM   2550 C  CA  . SER A 1 335 ? 94.42064  -27.03184 -43.27856 1.000 73.11483  ? 335 SER A CA  1 
ATOM   2551 C  C   . SER A 1 335 ? 95.40730  -27.02071 -44.44429 1.000 72.46504  ? 335 SER A C   1 
ATOM   2552 O  O   . SER A 1 335 ? 96.57212  -26.65157 -44.28405 1.000 71.77776  ? 335 SER A O   1 
ATOM   2553 C  CB  . SER A 1 335 ? 94.13404  -28.46967 -42.83820 1.000 73.18841  ? 335 SER A CB  1 
ATOM   2554 O  OG  . SER A 1 335 ? 93.49590  -29.20055 -43.86901 1.000 82.76611  ? 335 SER A OG  1 
ATOM   2555 N  N   . VAL B 1 5   ? 78.35680  -43.51870 7.70835   1.000 79.22280  ? 5   VAL B N   1 
ATOM   2556 C  CA  . VAL B 1 5   ? 78.40261  -42.33974 6.85201   1.000 71.58814  ? 5   VAL B CA  1 
ATOM   2557 C  C   . VAL B 1 5   ? 77.17544  -41.46949 7.08947   1.000 71.02668  ? 5   VAL B C   1 
ATOM   2558 O  O   . VAL B 1 5   ? 76.09646  -41.74931 6.56619   1.000 73.89986  ? 5   VAL B O   1 
ATOM   2559 C  CB  . VAL B 1 5   ? 78.50709  -42.72901 5.36457   1.000 67.89907  ? 5   VAL B CB  1 
ATOM   2560 C  CG1 . VAL B 1 5   ? 78.83518  -41.50663 4.51803   1.000 61.13636  ? 5   VAL B CG1 1 
ATOM   2561 C  CG2 . VAL B 1 5   ? 79.54759  -43.82089 5.16654   1.000 71.28620  ? 5   VAL B CG2 1 
ATOM   2562 N  N   . ASP B 1 6   ? 77.34102  -40.41390 7.87939   1.000 59.68277  ? 6   ASP B N   1 
ATOM   2563 C  CA  . ASP B 1 6   ? 76.25919  -39.48900 8.17348   1.000 64.46295  ? 6   ASP B CA  1 
ATOM   2564 C  C   . ASP B 1 6   ? 76.50955  -38.14985 7.48839   1.000 59.82772  ? 6   ASP B C   1 
ATOM   2565 O  O   . ASP B 1 6   ? 77.62000  -37.85267 7.03856   1.000 57.35155  ? 6   ASP B O   1 
ATOM   2566 C  CB  . ASP B 1 6   ? 76.09985  -39.29550 9.68535   1.000 68.15470  ? 6   ASP B CB  1 
ATOM   2567 C  CG  . ASP B 1 6   ? 74.66957  -38.98230 10.08217  1.000 76.22721  ? 6   ASP B CG  1 
ATOM   2568 O  OD1 . ASP B 1 6   ? 73.82410  -38.81526 9.17554   1.000 68.73885  ? 6   ASP B OD1 1 
ATOM   2569 O  OD2 . ASP B 1 6   ? 74.38750  -38.90922 11.29723  1.000 81.68689  ? 6   ASP B OD2 1 
ATOM   2570 N  N   . PHE B 1 7   ? 75.45355  -37.34143 7.40808   1.000 53.71152  ? 7   PHE B N   1 
ATOM   2571 C  CA  . PHE B 1 7   ? 75.49947  -36.06111 6.71840   1.000 57.86475  ? 7   PHE B CA  1 
ATOM   2572 C  C   . PHE B 1 7   ? 74.83974  -34.98107 7.56454   1.000 51.95828  ? 7   PHE B C   1 
ATOM   2573 O  O   . PHE B 1 7   ? 74.03115  -35.25776 8.45398   1.000 56.70661  ? 7   PHE B O   1 
ATOM   2574 C  CB  . PHE B 1 7   ? 74.81387  -36.13677 5.34562   1.000 52.86539  ? 7   PHE B CB  1 
ATOM   2575 C  CG  . PHE B 1 7   ? 75.43477  -37.13756 4.41342   1.000 55.13709  ? 7   PHE B CG  1 
ATOM   2576 C  CD1 . PHE B 1 7   ? 76.44843  -36.76107 3.54723   1.000 52.20672  ? 7   PHE B CD1 1 
ATOM   2577 C  CD2 . PHE B 1 7   ? 75.00705  -38.45590 4.40487   1.000 52.59486  ? 7   PHE B CD2 1 
ATOM   2578 C  CE1 . PHE B 1 7   ? 77.02257  -37.68063 2.68655   1.000 57.62694  ? 7   PHE B CE1 1 
ATOM   2579 C  CE2 . PHE B 1 7   ? 75.57758  -39.37966 3.54972   1.000 57.00414  ? 7   PHE B CE2 1 
ATOM   2580 C  CZ  . PHE B 1 7   ? 76.58573  -38.99148 2.68941   1.000 57.19992  ? 7   PHE B CZ  1 
ATOM   2581 N  N   . HIS B 1 8   ? 75.19589  -33.73621 7.26140   1.000 53.94075  ? 8   HIS B N   1 
ATOM   2582 C  CA  . HIS B 1 8   ? 74.66729  -32.56511 7.95683   1.000 54.00216  ? 8   HIS B CA  1 
ATOM   2583 C  C   . HIS B 1 8   ? 73.46297  -32.04916 7.17564   1.000 54.45472  ? 8   HIS B C   1 
ATOM   2584 O  O   . HIS B 1 8   ? 73.61370  -31.36998 6.15726   1.000 55.56782  ? 8   HIS B O   1 
ATOM   2585 C  CB  . HIS B 1 8   ? 75.75304  -31.50333 8.09457   1.000 54.61745  ? 8   HIS B CB  1 
ATOM   2586 C  CG  . HIS B 1 8   ? 75.28115  -30.22603 8.71371   1.000 52.74232  ? 8   HIS B CG  1 
ATOM   2587 N  ND1 . HIS B 1 8   ? 74.69617  -30.17378 9.96032   1.000 60.70369  ? 8   HIS B ND1 1 
ATOM   2588 C  CD2 . HIS B 1 8   ? 75.31467  -28.95063 8.25979   1.000 56.13409  ? 8   HIS B CD2 1 
ATOM   2589 C  CE1 . HIS B 1 8   ? 74.38681  -28.92161 10.24670  1.000 61.81278  ? 8   HIS B CE1 1 
ATOM   2590 N  NE2 . HIS B 1 8   ? 74.75136  -28.15935 9.23107   1.000 61.60896  ? 8   HIS B NE2 1 
ATOM   2591 N  N   . ILE B 1 9   ? 72.26269  -32.37760 7.64749   1.000 52.51623  ? 9   ILE B N   1 
ATOM   2592 C  CA  . ILE B 1 9   ? 71.02336  -31.97945 6.98068   1.000 52.04930  ? 9   ILE B CA  1 
ATOM   2593 C  C   . ILE B 1 9   ? 70.16192  -31.20063 7.96938   1.000 53.79685  ? 9   ILE B C   1 
ATOM   2594 O  O   . ILE B 1 9   ? 69.27978  -31.78593 8.61398   1.000 49.82974  ? 9   ILE B O   1 
ATOM   2595 C  CB  . ILE B 1 9   ? 70.26454  -33.19940 6.43023   1.000 55.84529  ? 9   ILE B CB  1 
ATOM   2596 C  CG1 . ILE B 1 9   ? 71.20822  -34.12775 5.66150   1.000 53.02038  ? 9   ILE B CG1 1 
ATOM   2597 C  CG2 . ILE B 1 9   ? 69.11821  -32.75779 5.52605   1.000 49.36960  ? 9   ILE B CG2 1 
ATOM   2598 C  CD1 . ILE B 1 9   ? 71.75320  -33.53097 4.38142   1.000 48.44065  ? 9   ILE B CD1 1 
ATOM   2599 N  N   . PRO B 1 10  ? 70.37304  -29.89062 8.12588   1.000 54.59035  ? 10  PRO B N   1 
ATOM   2600 C  CA  . PRO B 1 10  ? 69.60337  -29.11865 9.12641   1.000 51.10452  ? 10  PRO B CA  1 
ATOM   2601 C  C   . PRO B 1 10  ? 68.22469  -28.71787 8.61400   1.000 50.51128  ? 10  PRO B C   1 
ATOM   2602 O  O   . PRO B 1 10  ? 67.90020  -27.54161 8.42781   1.000 52.17100  ? 10  PRO B O   1 
ATOM   2603 C  CB  . PRO B 1 10  ? 70.51345  -27.91295 9.37628   1.000 48.11548  ? 10  PRO B CB  1 
ATOM   2604 C  CG  . PRO B 1 10  ? 71.18983  -27.69326 8.05301   1.000 52.41109  ? 10  PRO B CG  1 
ATOM   2605 C  CD  . PRO B 1 10  ? 71.37835  -29.06047 7.43632   1.000 49.16156  ? 10  PRO B CD  1 
ATOM   2606 N  N   . LEU B 1 11  ? 67.38523  -29.71902 8.37200   1.000 48.93528  ? 11  LEU B N   1 
ATOM   2607 C  CA  . LEU B 1 11  ? 66.02625  -29.53347 7.88773   1.000 44.82065  ? 11  LEU B CA  1 
ATOM   2608 C  C   . LEU B 1 11  ? 65.11903  -30.50693 8.62009   1.000 46.81794  ? 11  LEU B C   1 
ATOM   2609 O  O   . LEU B 1 11  ? 65.54516  -31.61639 8.96225   1.000 53.42017  ? 11  LEU B O   1 
ATOM   2610 C  CB  . LEU B 1 11  ? 65.91751  -29.76764 6.37140   1.000 46.27150  ? 11  LEU B CB  1 
ATOM   2611 C  CG  . LEU B 1 11  ? 66.74735  -28.86986 5.45337   1.000 51.80920  ? 11  LEU B CG  1 
ATOM   2612 C  CD1 . LEU B 1 11  ? 66.64713  -29.35412 4.00832   1.000 45.12037  ? 11  LEU B CD1 1 
ATOM   2613 C  CD2 . LEU B 1 11  ? 66.30547  -27.41499 5.57429   1.000 46.45112  ? 11  LEU B CD2 1 
ATOM   2614 N  N   . PRO B 1 12  ? 63.87101  -30.12485 8.87965   1.000 50.39085  ? 12  PRO B N   1 
ATOM   2615 C  CA  . PRO B 1 12  ? 62.98762  -31.00207 9.65533   1.000 50.90218  ? 12  PRO B CA  1 
ATOM   2616 C  C   . PRO B 1 12  ? 62.50346  -32.18357 8.83044   1.000 52.13696  ? 12  PRO B C   1 
ATOM   2617 O  O   . PRO B 1 12  ? 62.13556  -32.04249 7.66136   1.000 50.10954  ? 12  PRO B O   1 
ATOM   2618 C  CB  . PRO B 1 12  ? 61.82641  -30.08082 10.04030  1.000 47.51146  ? 12  PRO B CB  1 
ATOM   2619 C  CG  . PRO B 1 12  ? 61.77443  -29.08490 8.92167   1.000 46.83145  ? 12  PRO B CG  1 
ATOM   2620 C  CD  . PRO B 1 12  ? 63.20826  -28.86344 8.50220   1.000 47.21013  ? 12  PRO B CD  1 
ATOM   2621 N  N   . GLY B 1 13  ? 62.50769  -33.35773 9.45498   1.000 53.46263  ? 13  GLY B N   1 
ATOM   2622 C  CA  . GLY B 1 13  ? 61.90338  -34.51997 8.83076   1.000 51.01984  ? 13  GLY B CA  1 
ATOM   2623 C  C   . GLY B 1 13  ? 60.38653  -34.44308 8.88202   1.000 48.33991  ? 13  GLY B C   1 
ATOM   2624 O  O   . GLY B 1 13  ? 59.79362  -34.02968 9.87944   1.000 55.19544  ? 13  GLY B O   1 
ATOM   2625 N  N   . ARG B 1 14  ? 59.75399  -34.84176 7.78357   1.000 48.96359  ? 14  ARG B N   1 
ATOM   2626 C  CA  . ARG B 1 14  ? 58.30368  -34.83257 7.68101   1.000 49.05103  ? 14  ARG B CA  1 
ATOM   2627 C  C   . ARG B 1 14  ? 57.85400  -36.09626 6.96381   1.000 55.22006  ? 14  ARG B C   1 
ATOM   2628 O  O   . ARG B 1 14  ? 58.60985  -36.70713 6.20340   1.000 53.76580  ? 14  ARG B O   1 
ATOM   2629 C  CB  . ARG B 1 14  ? 57.79113  -33.58916 6.93677   1.000 46.56091  ? 14  ARG B CB  1 
ATOM   2630 C  CG  . ARG B 1 14  ? 58.11152  -32.26479 7.61676   1.000 48.12315  ? 14  ARG B CG  1 
ATOM   2631 C  CD  . ARG B 1 14  ? 57.90232  -31.09458 6.66752   1.000 45.43805  ? 14  ARG B CD  1 
ATOM   2632 N  NE  . ARG B 1 14  ? 56.51727  -30.98357 6.22653   1.000 41.78202  ? 14  ARG B NE  1 
ATOM   2633 C  CZ  . ARG B 1 14  ? 56.10823  -30.19332 5.24386   1.000 48.00841  ? 14  ARG B CZ  1 
ATOM   2634 N  NH1 . ARG B 1 14  ? 56.95627  -29.43296 4.57046   1.000 48.54784  ? 14  ARG B NH1 1 
ATOM   2635 N  NH2 . ARG B 1 14  ? 54.81745  -30.17002 4.92405   1.000 49.09088  ? 14  ARG B NH2 1 
ATOM   2636 N  N   . GLN B 1 15  ? 56.60896  -36.48790 7.21924   1.000 46.64239  ? 15  GLN B N   1 
ATOM   2637 C  CA  . GLN B 1 15  ? 56.01228  -37.61600 6.52231   1.000 51.80834  ? 15  GLN B CA  1 
ATOM   2638 C  C   . GLN B 1 15  ? 54.51504  -37.38507 6.40731   1.000 52.38743  ? 15  GLN B C   1 
ATOM   2639 O  O   . GLN B 1 15  ? 53.88929  -36.85908 7.33153   1.000 51.99350  ? 15  GLN B O   1 
ATOM   2640 C  CB  . GLN B 1 15  ? 56.28753  -38.94455 7.23615   1.000 47.41032  ? 15  GLN B CB  1 
ATOM   2641 C  CG  . GLN B 1 15  ? 55.80828  -40.16208 6.44938   1.000 51.84948  ? 15  GLN B CG  1 
ATOM   2642 C  CD  . GLN B 1 15  ? 56.14225  -41.47704 7.12779   1.000 57.54151  ? 15  GLN B CD  1 
ATOM   2643 O  OE1 . GLN B 1 15  ? 56.11207  -41.58285 8.35339   1.000 58.08237  ? 15  GLN B OE1 1 
ATOM   2644 N  NE2 . GLN B 1 15  ? 56.46602  -42.48827 6.32932   1.000 54.79705  ? 15  GLN B NE2 1 
ATOM   2645 N  N   . SER B 1 16  ? 53.95517  -37.77095 5.26595   1.000 50.98379  ? 16  SER B N   1 
ATOM   2646 C  CA  . SER B 1 16  ? 52.51859  -37.66876 5.07377   1.000 52.73438  ? 16  SER B CA  1 
ATOM   2647 C  C   . SER B 1 16  ? 51.79443  -38.50180 6.12884   1.000 60.06419  ? 16  SER B C   1 
ATOM   2648 O  O   . SER B 1 16  ? 52.21611  -39.62409 6.43270   1.000 56.44617  ? 16  SER B O   1 
ATOM   2649 C  CB  . SER B 1 16  ? 52.12929  -38.14448 3.67357   1.000 53.75642  ? 16  SER B CB  1 
ATOM   2650 O  OG  . SER B 1 16  ? 50.72141  -38.16527 3.51118   1.000 53.66951  ? 16  SER B OG  1 
ATOM   2651 N  N   . PRO B 1 17  ? 50.71334  -37.98345 6.71718   1.000 60.44869  ? 17  PRO B N   1 
ATOM   2652 C  CA  . PRO B 1 17  ? 49.94340  -38.78937 7.67667   1.000 58.74744  ? 17  PRO B CA  1 
ATOM   2653 C  C   . PRO B 1 17  ? 49.21788  -39.95898 7.03178   1.000 60.48176  ? 17  PRO B C   1 
ATOM   2654 O  O   . PRO B 1 17  ? 48.72004  -40.83399 7.75238   1.000 60.93720  ? 17  PRO B O   1 
ATOM   2655 C  CB  . PRO B 1 17  ? 48.95566  -37.77643 8.26666   1.000 58.06658  ? 17  PRO B CB  1 
ATOM   2656 C  CG  . PRO B 1 17  ? 48.78097  -36.76097 7.17851   1.000 61.38241  ? 17  PRO B CG  1 
ATOM   2657 C  CD  . PRO B 1 17  ? 50.12516  -36.64946 6.50904   1.000 57.16555  ? 17  PRO B CD  1 
ATOM   2658 N  N   . ASP B 1 18  ? 49.15510  -40.00487 5.70196   1.000 58.74138  ? 18  ASP B N   1 
ATOM   2659 C  CA  . ASP B 1 18  ? 48.48822  -41.06513 4.96154   1.000 59.03486  ? 18  ASP B CA  1 
ATOM   2660 C  C   . ASP B 1 18  ? 49.46893  -42.12037 4.45630   1.000 58.42957  ? 18  ASP B C   1 
ATOM   2661 O  O   . ASP B 1 18  ? 49.14928  -42.85746 3.51718   1.000 57.43678  ? 18  ASP B O   1 
ATOM   2662 C  CB  . ASP B 1 18  ? 47.70965  -40.45546 3.79442   1.000 54.68548  ? 18  ASP B CB  1 
ATOM   2663 C  CG  . ASP B 1 18  ? 46.58089  -41.33951 3.31552   1.000 61.64318  ? 18  ASP B CG  1 
ATOM   2664 O  OD1 . ASP B 1 18  ? 46.20771  -42.28117 4.04688   1.000 59.32461  ? 18  ASP B OD1 1 
ATOM   2665 O  OD2 . ASP B 1 18  ? 46.06869  -41.09192 2.20280   1.000 59.61441  ? 18  ASP B OD2 1 
ATOM   2666 N  N   . HIS B 1 19  ? 50.65047  -42.21505 5.07441   1.000 56.71184  ? 19  HIS B N   1 
ATOM   2667 C  CA  A HIS B 1 19  ? 51.69060  -43.10382 4.56474   0.562 55.31191  ? 19  HIS B CA  1 
ATOM   2668 C  CA  B HIS B 1 19  ? 51.68678  -43.10440 4.55821   0.438 55.29121  ? 19  HIS B CA  1 
ATOM   2669 C  C   . HIS B 1 19  ? 51.26553  -44.56637 4.62900   1.000 58.42163  ? 19  HIS B C   1 
ATOM   2670 O  O   . HIS B 1 19  ? 51.56973  -45.34893 3.72055   1.000 55.31908  ? 19  HIS B O   1 
ATOM   2671 C  CB  A HIS B 1 19  ? 52.98562  -42.88894 5.34816   0.562 55.58701  ? 19  HIS B CB  1 
ATOM   2672 C  CB  B HIS B 1 19  ? 52.99387  -42.89959 5.32176   0.438 55.61071  ? 19  HIS B CB  1 
ATOM   2673 C  CG  A HIS B 1 19  ? 52.85371  -43.15315 6.81588   0.562 56.23400  ? 19  HIS B CG  1 
ATOM   2674 C  CG  B HIS B 1 19  ? 53.96232  -44.02979 5.15993   0.438 56.77749  ? 19  HIS B CG  1 
ATOM   2675 N  ND1 A HIS B 1 19  ? 53.02294  -44.40582 7.36532   0.562 57.26277  ? 19  HIS B ND1 1 
ATOM   2676 N  ND1 B HIS B 1 19  ? 54.30613  -44.86993 6.19690   0.438 56.60404  ? 19  HIS B ND1 1 
ATOM   2677 C  CD2 A HIS B 1 19  ? 52.56184  -42.32646 7.84783   0.562 58.20107  ? 19  HIS B CD2 1 
ATOM   2678 C  CD2 B HIS B 1 19  ? 54.64262  -44.47253 4.07595   0.438 53.64076  ? 19  HIS B CD2 1 
ATOM   2679 C  CE1 A HIS B 1 19  ? 52.84416  -44.33890 8.67259   0.562 54.33160  ? 19  HIS B CE1 1 
ATOM   2680 C  CE1 B HIS B 1 19  ? 55.16606  -45.77372 5.76199   0.438 56.94309  ? 19  HIS B CE1 1 
ATOM   2681 N  NE2 A HIS B 1 19  ? 52.56331  -43.08823 8.99099   0.562 52.59006  ? 19  HIS B NE2 1 
ATOM   2682 N  NE2 B HIS B 1 19  ? 55.38653  -45.55512 4.47825   0.438 53.16761  ? 19  HIS B NE2 1 
ATOM   2683 N  N   . ALA B 1 20  ? 50.56634  -44.95614 5.69911   1.000 55.92856  ? 20  ALA B N   1 
ATOM   2684 C  CA  . ALA B 1 20  ? 50.22633  -46.36399 5.89750   1.000 53.66226  ? 20  ALA B CA  1 
ATOM   2685 C  C   . ALA B 1 20  ? 49.33205  -46.88994 4.77961   1.000 52.98717  ? 20  ALA B C   1 
ATOM   2686 O  O   . ALA B 1 20  ? 49.57005  -47.97777 4.24145   1.000 52.45073  ? 20  ALA B O   1 
ATOM   2687 C  CB  . ALA B 1 20  ? 49.55941  -46.55702 7.26077   1.000 54.34220  ? 20  ALA B CB  1 
ATOM   2688 N  N   . ARG B 1 21  ? 48.29286  -46.13428 4.41658   1.000 53.47641  ? 21  ARG B N   1 
ATOM   2689 C  CA  . ARG B 1 21  ? 47.41080  -46.57511 3.33978   1.000 52.85959  ? 21  ARG B CA  1 
ATOM   2690 C  C   . ARG B 1 21  ? 48.15242  -46.63051 2.00866   1.000 56.01115  ? 21  ARG B C   1 
ATOM   2691 O  O   . ARG B 1 21  ? 48.04648  -47.61443 1.26654   1.000 56.30315  ? 21  ARG B O   1 
ATOM   2692 C  CB  . ARG B 1 21  ? 46.19586  -45.65474 3.23074   1.000 50.22253  ? 21  ARG B CB  1 
ATOM   2693 C  CG  . ARG B 1 21  ? 45.23092  -46.08192 2.13311   1.000 48.36821  ? 21  ARG B CG  1 
ATOM   2694 C  CD  . ARG B 1 21  ? 44.42635  -44.91603 1.58328   1.000 55.09478  ? 21  ARG B CD  1 
ATOM   2695 N  NE  . ARG B 1 21  ? 45.27501  -43.81957 1.13086   1.000 57.07305  ? 21  ARG B NE  1 
ATOM   2696 C  CZ  . ARG B 1 21  ? 45.94877  -43.81168 -0.01139  1.000 57.40121  ? 21  ARG B CZ  1 
ATOM   2697 N  NH1 . ARG B 1 21  ? 45.92295  -44.84479 -0.83695  1.000 55.79994  ? 21  ARG B NH1 1 
ATOM   2698 N  NH2 . ARG B 1 21  ? 46.67063  -42.74150 -0.33131  1.000 54.50410  ? 21  ARG B NH2 1 
ATOM   2699 N  N   . ALA B 1 22  ? 48.90434  -45.57275 1.68622   1.000 56.27429  ? 22  ALA B N   1 
ATOM   2700 C  CA  . ALA B 1 22  ? 49.62813  -45.53208 0.41831   1.000 52.57353  ? 22  ALA B CA  1 
ATOM   2701 C  C   . ALA B 1 22  ? 50.62957  -46.67451 0.31928   1.000 51.59441  ? 22  ALA B C   1 
ATOM   2702 O  O   . ALA B 1 22  ? 50.79214  -47.28002 -0.74668  1.000 53.12669  ? 22  ALA B O   1 
ATOM   2703 C  CB  . ALA B 1 22  ? 50.33220  -44.18494 0.25880   1.000 51.50851  ? 22  ALA B CB  1 
ATOM   2704 N  N   . GLU B 1 23  ? 51.30235  -46.98893 1.42650   1.000 51.47626  ? 23  GLU B N   1 
ATOM   2705 C  CA  . GLU B 1 23  ? 52.23726  -48.10727 1.43706   1.000 52.19551  ? 23  GLU B CA  1 
ATOM   2706 C  C   . GLU B 1 23  ? 51.51920  -49.43110 1.20701   1.000 56.47597  ? 23  GLU B C   1 
ATOM   2707 O  O   . GLU B 1 23  ? 52.02624  -50.30650 0.49497   1.000 55.22069  ? 23  GLU B O   1 
ATOM   2708 C  CB  . GLU B 1 23  ? 53.00256  -48.11848 2.76029   1.000 57.02919  ? 23  GLU B CB  1 
ATOM   2709 C  CG  . GLU B 1 23  ? 53.91922  -49.30653 2.97091   1.000 60.07449  ? 23  GLU B CG  1 
ATOM   2710 C  CD  . GLU B 1 23  ? 54.94261  -49.04836 4.06225   1.000 72.36581  ? 23  GLU B CD  1 
ATOM   2711 O  OE1 . GLU B 1 23  ? 55.91517  -48.30509 3.80228   1.000 72.01838  ? 23  GLU B OE1 1 
ATOM   2712 O  OE2 . GLU B 1 23  ? 54.76633  -49.57124 5.18338   1.000 69.67562  ? 23  GLU B OE2 1 
ATOM   2713 N  N   . ALA B 1 24  ? 50.32301  -49.58412 1.77934   1.000 57.12021  ? 24  ALA B N   1 
ATOM   2714 C  CA  . ALA B 1 24  ? 49.60353  -50.84898 1.67511   1.000 54.81624  ? 24  ALA B CA  1 
ATOM   2715 C  C   . ALA B 1 24  ? 49.03398  -51.07383 0.27937   1.000 51.13548  ? 24  ALA B C   1 
ATOM   2716 O  O   . ALA B 1 24  ? 48.90872  -52.22434 -0.15511  1.000 54.03076  ? 24  ALA B O   1 
ATOM   2717 C  CB  . ALA B 1 24  ? 48.48522  -50.90139 2.71574   1.000 54.51833  ? 24  ALA B CB  1 
ATOM   2718 N  N   . GLU B 1 25  ? 48.69324  -50.00332 -0.43760  1.000 52.13713  ? 25  GLU B N   1 
ATOM   2719 C  CA  . GLU B 1 25  ? 48.03559  -50.10180 -1.73501  1.000 50.36830  ? 25  GLU B CA  1 
ATOM   2720 C  C   . GLU B 1 25  ? 48.98797  -49.90633 -2.91016  1.000 53.44479  ? 25  GLU B C   1 
ATOM   2721 O  O   . GLU B 1 25  ? 48.53006  -49.83000 -4.05510  1.000 51.33578  ? 25  GLU B O   1 
ATOM   2722 C  CB  . GLU B 1 25  ? 46.90186  -49.07777 -1.82599  1.000 50.72784  ? 25  GLU B CB  1 
ATOM   2723 C  CG  . GLU B 1 25  ? 45.82087  -49.23101 -0.76580  1.000 58.17045  ? 25  GLU B CG  1 
ATOM   2724 C  CD  . GLU B 1 25  ? 44.72010  -48.19694 -0.91181  1.000 61.88545  ? 25  GLU B CD  1 
ATOM   2725 O  OE1 . GLU B 1 25  ? 44.94157  -47.19004 -1.61631  1.000 66.54973  ? 25  GLU B OE1 1 
ATOM   2726 O  OE2 . GLU B 1 25  ? 43.63327  -48.39074 -0.32871  1.000 69.89767  ? 25  GLU B OE2 1 
ATOM   2727 N  N   . GLN B 1 26  ? 50.29847  -49.84469 -2.65931  1.000 53.20709  ? 26  GLN B N   1 
ATOM   2728 C  CA  . GLN B 1 26  ? 51.23021  -49.37973 -3.68422  1.000 50.19575  ? 26  GLN B CA  1 
ATOM   2729 C  C   . GLN B 1 26  ? 51.33081  -50.33780 -4.86630  1.000 51.26050  ? 26  GLN B C   1 
ATOM   2730 O  O   . GLN B 1 26  ? 51.60386  -49.89819 -5.98775  1.000 47.40177  ? 26  GLN B O   1 
ATOM   2731 C  CB  . GLN B 1 26  ? 52.61563  -49.16100 -3.07495  1.000 45.52902  ? 26  GLN B CB  1 
ATOM   2732 C  CG  . GLN B 1 26  ? 53.30402  -50.43912 -2.62406  1.000 46.18125  ? 26  GLN B CG  1 
ATOM   2733 C  CD  . GLN B 1 26  ? 54.68863  -50.19385 -2.06712  1.000 49.43596  ? 26  GLN B CD  1 
ATOM   2734 O  OE1 . GLN B 1 26  ? 55.65516  -50.03822 -2.81700  1.000 46.33307  ? 26  GLN B OE1 1 
ATOM   2735 N  NE2 . GLN B 1 26  ? 54.79464  -50.15925 -0.74286  1.000 49.46473  ? 26  GLN B NE2 1 
ATOM   2736 N  N   . LEU B 1 27  ? 51.11536  -51.63651 -4.64852  1.000 49.17672  ? 27  LEU B N   1 
ATOM   2737 C  CA  . LEU B 1 27  ? 51.40606  -52.62076 -5.68507  1.000 46.82679  ? 27  LEU B CA  1 
ATOM   2738 C  C   . LEU B 1 27  ? 50.33816  -52.69764 -6.76649  1.000 45.98091  ? 27  LEU B C   1 
ATOM   2739 O  O   . LEU B 1 27  ? 50.61977  -53.21785 -7.85135  1.000 51.16753  ? 27  LEU B O   1 
ATOM   2740 C  CB  . LEU B 1 27  ? 51.59280  -54.00482 -5.06049  1.000 48.14132  ? 27  LEU B CB  1 
ATOM   2741 C  CG  . LEU B 1 27  ? 52.86533  -54.20322 -4.23961  1.000 49.99983  ? 27  LEU B CG  1 
ATOM   2742 C  CD1 . LEU B 1 27  ? 52.94014  -55.62668 -3.69720  1.000 47.67492  ? 27  LEU B CD1 1 
ATOM   2743 C  CD2 . LEU B 1 27  ? 54.08499  -53.87399 -5.08677  1.000 43.54794  ? 27  LEU B CD2 1 
ATOM   2744 N  N   . ALA B 1 28  ? 49.13056  -52.19367 -6.50421  1.000 53.61278  ? 28  ALA B N   1 
ATOM   2745 C  CA  . ALA B 1 28  ? 48.03514  -52.35575 -7.45682  1.000 51.23802  ? 28  ALA B CA  1 
ATOM   2746 C  C   . ALA B 1 28  ? 48.35900  -51.70284 -8.79662  1.000 49.61947  ? 28  ALA B C   1 
ATOM   2747 O  O   . ALA B 1 28  ? 48.15028  -52.30216 -9.85881  1.000 52.06243  ? 28  ALA B O   1 
ATOM   2748 C  CB  . ALA B 1 28  ? 46.74367  -51.78172 -6.87284  1.000 46.71691  ? 28  ALA B CB  1 
ATOM   2749 N  N   . TRP B 1 29  ? 48.87991  -50.47665 -8.76728  1.000 45.92248  ? 29  TRP B N   1 
ATOM   2750 C  CA  . TRP B 1 29  ? 49.13763  -49.75955 -10.01512 1.000 48.69400  ? 29  TRP B CA  1 
ATOM   2751 C  C   . TRP B 1 29  ? 50.19299  -50.43398 -10.88485 1.000 49.65287  ? 29  TRP B C   1 
ATOM   2752 O  O   . TRP B 1 29  ? 49.92974  -50.63342 -12.08333 1.000 52.11834  ? 29  TRP B O   1 
ATOM   2753 C  CB  . TRP B 1 29  ? 49.50528  -48.30379 -9.70809  1.000 49.31291  ? 29  TRP B CB  1 
ATOM   2754 C  CG  . TRP B 1 29  ? 49.79490  -47.49676 -10.93426 1.000 52.55118  ? 29  TRP B CG  1 
ATOM   2755 C  CD1 . TRP B 1 29  ? 48.88274  -46.91048 -11.76199 1.000 52.31500  ? 29  TRP B CD1 1 
ATOM   2756 C  CD2 . TRP B 1 29  ? 51.08582  -47.18499 -11.47418 1.000 49.97779  ? 29  TRP B CD2 1 
ATOM   2757 N  NE1 . TRP B 1 29  ? 49.52370  -46.25407 -12.78346 1.000 51.96559  ? 29  TRP B NE1 1 
ATOM   2758 C  CE2 . TRP B 1 29  ? 50.87671  -46.40553 -12.62964 1.000 48.85429  ? 29  TRP B CE2 1 
ATOM   2759 C  CE3 . TRP B 1 29  ? 52.39697  -47.48700 -11.09182 1.000 48.98768  ? 29  TRP B CE3 1 
ATOM   2760 C  CZ2 . TRP B 1 29  ? 51.92920  -45.92379 -13.40706 1.000 50.11225  ? 29  TRP B CZ2 1 
ATOM   2761 C  CZ3 . TRP B 1 29  ? 53.44139  -47.00777 -11.86673 1.000 48.75573  ? 29  TRP B CZ3 1 
ATOM   2762 C  CH2 . TRP B 1 29  ? 53.20027  -46.23672 -13.01067 1.000 47.47301  ? 29  TRP B CH2 1 
ATOM   2763 N  N   . PRO B 1 30  ? 51.38082  -50.80246 -10.38378 1.000 49.03804  ? 30  PRO B N   1 
ATOM   2764 C  CA  . PRO B 1 30  ? 52.34298  -51.48445 -11.26706 1.000 45.79517  ? 30  PRO B CA  1 
ATOM   2765 C  C   . PRO B 1 30  ? 51.89549  -52.87383 -11.69317 1.000 49.30320  ? 30  PRO B C   1 
ATOM   2766 O  O   . PRO B 1 30  ? 52.24585  -53.30693 -12.79830 1.000 46.54328  ? 30  PRO B O   1 
ATOM   2767 C  CB  . PRO B 1 30  ? 53.62508  -51.53587 -10.42393 1.000 41.63643  ? 30  PRO B CB  1 
ATOM   2768 C  CG  . PRO B 1 30  ? 53.15227  -51.45122 -9.01294  1.000 42.80103  ? 30  PRO B CG  1 
ATOM   2769 C  CD  . PRO B 1 30  ? 51.95959  -50.54553 -9.05139  1.000 45.31211  ? 30  PRO B CD  1 
ATOM   2770 N  N   . ARG B 1 31  ? 51.13764  -53.58869 -10.85488 1.000 50.34413  ? 31  ARG B N   1 
ATOM   2771 C  CA  . ARG B 1 31  ? 50.62788  -54.89690 -11.25822 1.000 48.50613  ? 31  ARG B CA  1 
ATOM   2772 C  C   . ARG B 1 31  ? 49.63627  -54.77419 -12.40886 1.000 51.29956  ? 31  ARG B C   1 
ATOM   2773 O  O   . ARG B 1 31  ? 49.62054  -55.61586 -13.31493 1.000 51.48992  ? 31  ARG B O   1 
ATOM   2774 C  CB  . ARG B 1 31  ? 49.96362  -55.60329 -10.07721 1.000 49.48086  ? 31  ARG B CB  1 
ATOM   2775 C  CG  . ARG B 1 31  ? 50.90096  -56.17338 -9.02186  1.000 55.40767  ? 31  ARG B CG  1 
ATOM   2776 C  CD  . ARG B 1 31  ? 50.19674  -57.32187 -8.30734  1.000 56.69973  ? 31  ARG B CD  1 
ATOM   2777 N  NE  . ARG B 1 31  ? 50.69144  -57.58382 -6.96133  1.000 55.14556  ? 31  ARG B NE  1 
ATOM   2778 C  CZ  . ARG B 1 31  ? 51.51300  -58.57455 -6.64069  1.000 65.42660  ? 31  ARG B CZ  1 
ATOM   2779 N  NH1 . ARG B 1 31  ? 52.01737  -59.38252 -7.55977  1.000 62.03276  ? 31  ARG B NH1 1 
ATOM   2780 N  NH2 . ARG B 1 31  ? 51.82976  -58.76529 -5.36374  1.000 57.26961  ? 31  ARG B NH2 1 
ATOM   2781 N  N   . SER B 1 32  ? 48.79585  -53.73664 -12.38626 1.000 51.89912  ? 32  SER B N   1 
ATOM   2782 C  CA  . SER B 1 32  ? 47.79071  -53.56250 -13.42824 1.000 50.51868  ? 32  SER B CA  1 
ATOM   2783 C  C   . SER B 1 32  ? 48.40830  -53.30455 -14.79450 1.000 54.80633  ? 32  SER B C   1 
ATOM   2784 O  O   . SER B 1 32  ? 47.73552  -53.50281 -15.81141 1.000 56.65189  ? 32  SER B O   1 
ATOM   2785 C  CB  . SER B 1 32  ? 46.85067  -52.41239 -13.06886 1.000 52.12282  ? 32  SER B CB  1 
ATOM   2786 O  OG  . SER B 1 32  ? 47.51125  -51.16392 -13.18218 1.000 53.28750  ? 32  SER B OG  1 
ATOM   2787 N  N   . LEU B 1 33  ? 49.66427  -52.86374 -14.84144 1.000 53.92571  ? 33  LEU B N   1 
ATOM   2788 C  CA  . LEU B 1 33  ? 50.35467  -52.61095 -16.09629 1.000 50.85041  ? 33  LEU B CA  1 
ATOM   2789 C  C   . LEU B 1 33  ? 51.25542  -53.75948 -16.52220 1.000 47.53635  ? 33  LEU B C   1 
ATOM   2790 O  O   . LEU B 1 33  ? 51.81681  -53.70784 -17.62078 1.000 55.59045  ? 33  LEU B O   1 
ATOM   2791 C  CB  . LEU B 1 33  ? 51.19035  -51.33021 -15.98831 1.000 55.71948  ? 33  LEU B CB  1 
ATOM   2792 C  CG  . LEU B 1 33  ? 50.40813  -50.03376 -15.78149 1.000 57.11914  ? 33  LEU B CG  1 
ATOM   2793 C  CD1 . LEU B 1 33  ? 51.26569  -48.99600 -15.07704 1.000 52.02449  ? 33  LEU B CD1 1 
ATOM   2794 C  CD2 . LEU B 1 33  ? 49.91204  -49.50653 -17.11710 1.000 50.49599  ? 33  LEU B CD2 1 
ATOM   2795 N  N   . GLY B 1 34  ? 51.41183  -54.78273 -15.68589 1.000 49.27073  ? 34  GLY B N   1 
ATOM   2796 C  CA  . GLY B 1 34  ? 52.33989  -55.85511 -15.97089 1.000 45.86000  ? 34  GLY B CA  1 
ATOM   2797 C  C   . GLY B 1 34  ? 53.77786  -55.56763 -15.60813 1.000 45.70634  ? 34  GLY B C   1 
ATOM   2798 O  O   . GLY B 1 34  ? 54.65003  -56.38863 -15.91340 1.000 49.29110  ? 34  GLY B O   1 
ATOM   2799 N  N   . LEU B 1 35  ? 54.05537  -54.42364 -14.97355 1.000 44.72487  ? 35  LEU B N   1 
ATOM   2800 C  CA  . LEU B 1 35  ? 55.41719  -54.10951 -14.54833 1.000 42.03517  ? 35  LEU B CA  1 
ATOM   2801 C  C   . LEU B 1 35  ? 55.88028  -55.02408 -13.42121 1.000 40.08302  ? 35  LEU B C   1 
ATOM   2802 O  O   . LEU B 1 35  ? 57.07980  -55.29531 -13.29444 1.000 42.69803  ? 35  LEU B O   1 
ATOM   2803 C  CB  . LEU B 1 35  ? 55.50224  -52.64672 -14.11475 1.000 46.23722  ? 35  LEU B CB  1 
ATOM   2804 C  CG  . LEU B 1 35  ? 55.14171  -51.62230 -15.19266 1.000 48.25096  ? 35  LEU B CG  1 
ATOM   2805 C  CD1 . LEU B 1 35  ? 55.11100  -50.21501 -14.61104 1.000 48.36453  ? 35  LEU B CD1 1 
ATOM   2806 C  CD2 . LEU B 1 35  ? 56.11285  -51.71055 -16.36214 1.000 43.17685  ? 35  LEU B CD2 1 
ATOM   2807 N  N   . ILE B 1 36  ? 54.95176  -55.50762 -12.60164 1.000 45.86080  ? 36  ILE B N   1 
ATOM   2808 C  CA  . ILE B 1 36  ? 55.23584  -56.47661 -11.55101 1.000 42.23167  ? 36  ILE B CA  1 
ATOM   2809 C  C   . ILE B 1 36  ? 54.27395  -57.64357 -11.72152 1.000 46.20201  ? 36  ILE B C   1 
ATOM   2810 O  O   . ILE B 1 36  ? 53.05637  -57.44195 -11.77786 1.000 49.94752  ? 36  ILE B O   1 
ATOM   2811 C  CB  . ILE B 1 36  ? 55.09070  -55.85577 -10.14882 1.000 42.86178  ? 36  ILE B CB  1 
ATOM   2812 C  CG1 . ILE B 1 36  ? 56.14025  -54.76148 -9.93135  1.000 39.69455  ? 36  ILE B CG1 1 
ATOM   2813 C  CG2 . ILE B 1 36  ? 55.17768  -56.93327 -9.07329  1.000 46.10520  ? 36  ILE B CG2 1 
ATOM   2814 C  CD1 . ILE B 1 36  ? 55.94900  -54.00033 -8.63931  1.000 40.83033  ? 36  ILE B CD1 1 
ATOM   2815 N  N   . ARG B 1 37  ? 54.81304  -58.85915 -11.80735 1.000 44.54593  ? 37  ARG B N   1 
ATOM   2816 C  CA  . ARG B 1 37  ? 53.96362  -60.02862 -12.00080 1.000 47.22499  ? 37  ARG B CA  1 
ATOM   2817 C  C   . ARG B 1 37  ? 54.23187  -61.10554 -10.95912 1.000 42.66862  ? 37  ARG B C   1 
ATOM   2818 O  O   . ARG B 1 37  ? 53.30716  -61.55441 -10.27642 1.000 47.84298  ? 37  ARG B O   1 
ATOM   2819 C  CB  . ARG B 1 37  ? 54.14570  -60.60522 -13.40814 1.000 44.37223  ? 37  ARG B CB  1 
ATOM   2820 C  CG  . ARG B 1 37  ? 53.44724  -59.80931 -14.50037 1.000 48.19832  ? 37  ARG B CG  1 
ATOM   2821 C  CD  . ARG B 1 37  ? 53.23277  -60.65695 -15.74525 1.000 50.69080  ? 37  ARG B CD  1 
ATOM   2822 N  NE  . ARG B 1 37  ? 53.75047  -60.01132 -16.94529 1.000 58.01331  ? 37  ARG B NE  1 
ATOM   2823 C  CZ  . ARG B 1 37  ? 53.03140  -59.25556 -17.76273 1.000 54.81951  ? 37  ARG B CZ  1 
ATOM   2824 N  NH1 . ARG B 1 37  ? 51.74715  -59.02889 -17.54351 1.000 65.09161  ? 37  ARG B NH1 1 
ATOM   2825 N  NH2 . ARG B 1 37  ? 53.61598  -58.71468 -18.82772 1.000 58.11816  ? 37  ARG B NH2 1 
ATOM   2826 N  N   . SER B 1 38  ? 55.48266  -61.53652 -10.83645 1.000 39.96055  ? 38  SER B N   1 
ATOM   2827 C  CA  . SER B 1 38  ? 55.80131  -62.61456 -9.91475  1.000 46.28865  ? 38  SER B CA  1 
ATOM   2828 C  C   . SER B 1 38  ? 55.72588  -62.13006 -8.46811  1.000 46.47299  ? 38  SER B C   1 
ATOM   2829 O  O   . SER B 1 38  ? 55.77152  -60.93091 -8.18058  1.000 46.46339  ? 38  SER B O   1 
ATOM   2830 C  CB  . SER B 1 38  ? 57.19231  -63.17729 -10.20735 1.000 42.74637  ? 38  SER B CB  1 
ATOM   2831 O  OG  . SER B 1 38  ? 58.18989  -62.19994 -9.97497  1.000 40.89846  ? 38  SER B OG  1 
ATOM   2832 N  N   . ASP B 1 39  ? 55.60423  -63.09020 -7.54744  1.000 45.09670  ? 39  ASP B N   1 
ATOM   2833 C  CA  . ASP B 1 39  ? 55.62297  -62.75300 -6.12771  1.000 44.07824  ? 39  ASP B CA  1 
ATOM   2834 C  C   . ASP B 1 39  ? 56.96483  -62.15805 -5.72377  1.000 49.33428  ? 39  ASP B C   1 
ATOM   2835 O  O   . ASP B 1 39  ? 57.02053  -61.21567 -4.92383  1.000 45.24989  ? 39  ASP B O   1 
ATOM   2836 C  CB  . ASP B 1 39  ? 55.31755  -63.99268 -5.28470  1.000 50.64273  ? 39  ASP B CB  1 
ATOM   2837 C  CG  . ASP B 1 39  ? 56.28294  -65.14891 -5.55808  1.000 58.33152  ? 39  ASP B CG  1 
ATOM   2838 O  OD1 . ASP B 1 39  ? 57.04718  -65.08794 -6.54494  1.000 45.40249  ? 39  ASP B OD1 1 
ATOM   2839 O  OD2 . ASP B 1 39  ? 56.28087  -66.12539 -4.77824  1.000 67.61280  ? 39  ASP B OD2 1 
ATOM   2840 N  N   . ALA B 1 40  ? 58.05893  -62.69872 -6.26767  1.000 40.31359  ? 40  ALA B N   1 
ATOM   2841 C  CA  . ALA B 1 40  ? 59.38627  -62.21134 -5.90856  1.000 45.58963  ? 40  ALA B CA  1 
ATOM   2842 C  C   . ALA B 1 40  ? 59.60682  -60.78637 -6.40054  1.000 43.01083  ? 40  ALA B C   1 
ATOM   2843 O  O   . ALA B 1 40  ? 60.27656  -59.99168 -5.73077  1.000 43.97746  ? 40  ALA B O   1 
ATOM   2844 C  CB  . ALA B 1 40  ? 60.45762  -63.14732 -6.46575  1.000 41.13727  ? 40  ALA B CB  1 
ATOM   2845 N  N   . ALA B 1 41  ? 59.05877  -60.44471 -7.57038  1.000 38.00447  ? 41  ALA B N   1 
ATOM   2846 C  CA  . ALA B 1 41  ? 59.16161  -59.07084 -8.05149  1.000 43.30236  ? 41  ALA B CA  1 
ATOM   2847 C  C   . ALA B 1 41  ? 58.36140  -58.11526 -7.17839  1.000 45.65608  ? 41  ALA B C   1 
ATOM   2848 O  O   . ALA B 1 41  ? 58.74738  -56.95140 -7.02039  1.000 42.23337  ? 41  ALA B O   1 
ATOM   2849 C  CB  . ALA B 1 41  ? 58.69458  -58.97341 -9.50507  1.000 37.42177  ? 41  ALA B CB  1 
ATOM   2850 N  N   . ALA B 1 42  ? 57.24268  -58.58089 -6.61720  1.000 43.24422  ? 42  ALA B N   1 
ATOM   2851 C  CA  . ALA B 1 42  ? 56.47770  -57.74817 -5.69714  1.000 44.27671  ? 42  ALA B CA  1 
ATOM   2852 C  C   . ALA B 1 42  ? 57.24407  -57.51943 -4.40126  1.000 43.73262  ? 42  ALA B C   1 
ATOM   2853 O  O   . ALA B 1 42  ? 57.30142  -56.39119 -3.89908  1.000 44.44971  ? 42  ALA B O   1 
ATOM   2854 C  CB  . ALA B 1 42  ? 55.11887  -58.38791 -5.41513  1.000 46.91349  ? 42  ALA B CB  1 
ATOM   2855 N  N   . GLU B 1 43  ? 57.84645  -58.57649 -3.85015  1.000 45.55408  ? 43  GLU B N   1 
ATOM   2856 C  CA  . GLU B 1 43  ? 58.61854  -58.42938 -2.61972  1.000 48.40238  ? 43  GLU B CA  1 
ATOM   2857 C  C   . GLU B 1 43  ? 59.83714  -57.54366 -2.83791  1.000 53.21681  ? 43  GLU B C   1 
ATOM   2858 O  O   . GLU B 1 43  ? 60.15332  -56.69231 -1.99801  1.000 44.47194  ? 43  GLU B O   1 
ATOM   2859 C  CB  . GLU B 1 43  ? 59.04226  -59.80100 -2.09527  1.000 46.15209  ? 43  GLU B CB  1 
ATOM   2860 C  CG  . GLU B 1 43  ? 57.99045  -60.48623 -1.24857  1.000 68.02518  ? 43  GLU B CG  1 
ATOM   2861 C  CD  . GLU B 1 43  ? 57.72765  -59.74266 0.04529   1.000 74.00255  ? 43  GLU B CD  1 
ATOM   2862 O  OE1 . GLU B 1 43  ? 58.69766  -59.22160 0.63711   1.000 78.96257  ? 43  GLU B OE1 1 
ATOM   2863 O  OE2 . GLU B 1 43  ? 56.55358  -59.67050 0.46485   1.000 75.79126  ? 43  GLU B OE2 1 
ATOM   2864 N  N   . ARG B 1 44  ? 60.53901  -57.73809 -3.95815  1.000 44.34561  ? 44  ARG B N   1 
ATOM   2865 C  CA  . ARG B 1 44  ? 61.67370  -56.88122 -4.28226  1.000 45.95075  ? 44  ARG B CA  1 
ATOM   2866 C  C   . ARG B 1 44  ? 61.25284  -55.41946 -4.34699  1.000 47.71425  ? 44  ARG B C   1 
ATOM   2867 O  O   . ARG B 1 44  ? 61.97920  -54.53390 -3.87993  1.000 44.34128  ? 44  ARG B O   1 
ATOM   2868 C  CB  . ARG B 1 44  ? 62.29843  -57.32157 -5.60642  1.000 43.40016  ? 44  ARG B CB  1 
ATOM   2869 C  CG  . ARG B 1 44  ? 63.38515  -56.39320 -6.12210  1.000 45.01048  ? 44  ARG B CG  1 
ATOM   2870 C  CD  . ARG B 1 44  ? 64.02321  -56.94275 -7.38767  1.000 42.75454  ? 44  ARG B CD  1 
ATOM   2871 N  NE  . ARG B 1 44  ? 65.09610  -56.08587 -7.87750  1.000 43.09385  ? 44  ARG B NE  1 
ATOM   2872 C  CZ  . ARG B 1 44  ? 64.91952  -55.06887 -8.70979  1.000 41.35788  ? 44  ARG B CZ  1 
ATOM   2873 N  NH1 . ARG B 1 44  ? 63.71945  -54.75088 -9.16944  1.000 38.81690  ? 44  ARG B NH1 1 
ATOM   2874 N  NH2 . ARG B 1 44  ? 65.97269  -54.35193 -9.09057  1.000 47.57426  ? 44  ARG B NH2 1 
ATOM   2875 N  N   . HIS B 1 45  ? 60.07256  -55.14967 -4.91034  1.000 40.02303  ? 45  HIS B N   1 
ATOM   2876 C  CA  . HIS B 1 45  ? 59.57577  -53.77966 -4.96231  1.000 44.77943  ? 45  HIS B CA  1 
ATOM   2877 C  C   . HIS B 1 45  ? 59.29081  -53.23875 -3.56359  1.000 45.41421  ? 45  HIS B C   1 
ATOM   2878 O  O   . HIS B 1 45  ? 59.61311  -52.08437 -3.25949  1.000 44.61659  ? 45  HIS B O   1 
ATOM   2879 C  CB  . HIS B 1 45  ? 58.32063  -53.71817 -5.82936  1.000 39.54018  ? 45  HIS B CB  1 
ATOM   2880 C  CG  . HIS B 1 45  ? 57.93685  -52.33176 -6.24098  1.000 40.64634  ? 45  HIS B CG  1 
ATOM   2881 N  ND1 . HIS B 1 45  ? 58.52950  -51.67959 -7.30063  1.000 40.97989  ? 45  HIS B ND1 1 
ATOM   2882 C  CD2 . HIS B 1 45  ? 57.01814  -51.47371 -5.73791  1.000 36.39617  ? 45  HIS B CD2 1 
ATOM   2883 C  CE1 . HIS B 1 45  ? 57.99247  -50.47999 -7.43324  1.000 39.10371  ? 45  HIS B CE1 1 
ATOM   2884 N  NE2 . HIS B 1 45  ? 57.07365  -50.32922 -6.49606  1.000 38.52371  ? 45  HIS B NE2 1 
ATOM   2885 N  N   . LEU B 1 46  ? 58.69132  -54.06135 -2.69639  1.000 45.84345  ? 46  LEU B N   1 
ATOM   2886 C  CA  . LEU B 1 46  ? 58.35683  -53.60878 -1.34857  1.000 43.85535  ? 46  LEU B CA  1 
ATOM   2887 C  C   . LEU B 1 46  ? 59.60946  -53.30322 -0.53789  1.000 43.46054  ? 46  LEU B C   1 
ATOM   2888 O  O   . LEU B 1 46  ? 59.62381  -52.35706 0.25648   1.000 47.37805  ? 46  LEU B O   1 
ATOM   2889 C  CB  . LEU B 1 46  ? 57.50647  -54.65793 -0.62919  1.000 43.54041  ? 46  LEU B CB  1 
ATOM   2890 C  CG  . LEU B 1 46  ? 56.10056  -54.95653 -1.15326  1.000 47.43930  ? 46  LEU B CG  1 
ATOM   2891 C  CD1 . LEU B 1 46  ? 55.41672  -55.97295 -0.25183  1.000 48.70019  ? 46  LEU B CD1 1 
ATOM   2892 C  CD2 . LEU B 1 46  ? 55.27134  -53.68988 -1.25298  1.000 45.75629  ? 46  LEU B CD2 1 
ATOM   2893 N  N   . ARG B 1 47  ? 60.66976  -54.09349 -0.71914  1.000 40.82251  ? 47  ARG B N   1 
ATOM   2894 C  CA  . ARG B 1 47  ? 61.90684  -53.84502 0.01160   1.000 44.01556  ? 47  ARG B CA  1 
ATOM   2895 C  C   . ARG B 1 47  ? 62.54564  -52.51144 -0.35856  1.000 46.39114  ? 47  ARG B C   1 
ATOM   2896 O  O   . ARG B 1 47  ? 63.41501  -52.03188 0.37523   1.000 44.30018  ? 47  ARG B O   1 
ATOM   2897 C  CB  . ARG B 1 47  ? 62.90237  -54.98166 -0.22801  1.000 44.27094  ? 47  ARG B CB  1 
ATOM   2898 C  CG  . ARG B 1 47  ? 62.51193  -56.29705 0.43086   1.000 55.56703  ? 47  ARG B CG  1 
ATOM   2899 C  CD  . ARG B 1 47  ? 63.66080  -57.29956 0.39485   1.000 57.74911  ? 47  ARG B CD  1 
ATOM   2900 N  NE  . ARG B 1 47  ? 64.04883  -57.65514 -0.96584  1.000 65.97791  ? 47  ARG B NE  1 
ATOM   2901 C  CZ  . ARG B 1 47  ? 63.58517  -58.70618 -1.63026  1.000 63.78303  ? 47  ARG B CZ  1 
ATOM   2902 N  NH1 . ARG B 1 47  ? 62.71172  -59.53881 -1.08693  1.000 65.50977  ? 47  ARG B NH1 1 
ATOM   2903 N  NH2 . ARG B 1 47  ? 64.00856  -58.92745 -2.87159  1.000 55.93062  ? 47  ARG B NH2 1 
ATOM   2904 N  N   . GLY B 1 48  ? 62.14378  -51.90357 -1.47760  1.000 47.34796  ? 48  GLY B N   1 
ATOM   2905 C  CA  . GLY B 1 48  ? 62.67713  -50.60330 -1.84593  1.000 49.73631  ? 48  GLY B CA  1 
ATOM   2906 C  C   . GLY B 1 48  ? 62.12969  -49.45157 -1.02644  1.000 47.32964  ? 48  GLY B C   1 
ATOM   2907 O  O   . GLY B 1 48  ? 62.78072  -48.40528 -0.93978  1.000 45.03054  ? 48  GLY B O   1 
ATOM   2908 N  N   . GLY B 1 49  ? 60.95271  -49.61767 -0.42912  1.000 45.07025  ? 49  GLY B N   1 
ATOM   2909 C  CA  . GLY B 1 49  ? 60.35911  -48.56080 0.37939   1.000 40.10370  ? 49  GLY B CA  1 
ATOM   2910 C  C   . GLY B 1 49  ? 59.98770  -47.32533 -0.41066  1.000 49.10539  ? 49  GLY B C   1 
ATOM   2911 O  O   . GLY B 1 49  ? 60.21369  -46.20104 0.05367   1.000 45.59388  ? 49  GLY B O   1 
ATOM   2912 N  N   . TYR B 1 50  ? 59.40684  -47.50951 -1.59838  1.000 42.23275  ? 50  TYR B N   1 
ATOM   2913 C  CA  . TYR B 1 50  ? 59.13277  -46.38030 -2.48125  1.000 43.61119  ? 50  TYR B CA  1 
ATOM   2914 C  C   . TYR B 1 50  ? 57.92535  -45.57664 -2.01813  1.000 47.38282  ? 50  TYR B C   1 
ATOM   2915 O  O   . TYR B 1 50  ? 57.82714  -44.38177 -2.32060  1.000 47.27831  ? 50  TYR B O   1 
ATOM   2916 C  CB  . TYR B 1 50  ? 58.94574  -46.88454 -3.91393  1.000 41.14095  ? 50  TYR B CB  1 
ATOM   2917 C  CG  . TYR B 1 50  ? 60.13616  -47.68576 -4.37858  1.000 42.84890  ? 50  TYR B CG  1 
ATOM   2918 C  CD1 . TYR B 1 50  ? 61.41787  -47.15760 -4.29631  1.000 43.95514  ? 50  TYR B CD1 1 
ATOM   2919 C  CD2 . TYR B 1 50  ? 59.99002  -48.98169 -4.85336  1.000 42.22418  ? 50  TYR B CD2 1 
ATOM   2920 C  CE1 . TYR B 1 50  ? 62.51737  -47.88430 -4.69710  1.000 44.49475  ? 50  TYR B CE1 1 
ATOM   2921 C  CE2 . TYR B 1 50  ? 61.09002  -49.71953 -5.26027  1.000 44.44974  ? 50  TYR B CE2 1 
ATOM   2922 C  CZ  . TYR B 1 50  ? 62.35117  -49.16235 -5.17710  1.000 42.08209  ? 50  TYR B CZ  1 
ATOM   2923 O  OH  . TYR B 1 50  ? 63.45375  -49.88081 -5.57305  1.000 46.89268  ? 50  TYR B OH  1 
ATOM   2924 N  N   . ALA B 1 51  ? 57.00249  -46.20339 -1.28546  1.000 46.87191  ? 51  ALA B N   1 
ATOM   2925 C  CA  . ALA B 1 51  ? 55.90068  -45.44631 -0.70047  1.000 47.02152  ? 51  ALA B CA  1 
ATOM   2926 C  C   . ALA B 1 51  ? 56.37845  -44.61758 0.48546   1.000 46.27579  ? 51  ALA B C   1 
ATOM   2927 O  O   . ALA B 1 51  ? 55.89783  -43.49894 0.70329   1.000 45.17516  ? 51  ALA B O   1 
ATOM   2928 C  CB  . ALA B 1 51  ? 54.77450  -46.38896 -0.28551  1.000 41.76071  ? 51  ALA B CB  1 
ATOM   2929 N  N   . ASP B 1 52  ? 57.32462  -45.15046 1.26247   1.000 42.43314  ? 52  ASP B N   1 
ATOM   2930 C  CA  . ASP B 1 52  ? 57.95420  -44.35790 2.31354   1.000 47.31176  ? 52  ASP B CA  1 
ATOM   2931 C  C   . ASP B 1 52  ? 58.66470  -43.14435 1.72497   1.000 48.40924  ? 52  ASP B C   1 
ATOM   2932 O  O   . ASP B 1 52  ? 58.54434  -42.02618 2.23997   1.000 49.27091  ? 52  ASP B O   1 
ATOM   2933 C  CB  . ASP B 1 52  ? 58.93027  -45.22572 3.10785   1.000 45.20702  ? 52  ASP B CB  1 
ATOM   2934 C  CG  . ASP B 1 52  ? 59.69715  -44.43408 4.15045   1.000 52.26092  ? 52  ASP B CG  1 
ATOM   2935 O  OD1 . ASP B 1 52  ? 59.05007  -43.80270 5.01105   1.000 57.40381  ? 52  ASP B OD1 1 
ATOM   2936 O  OD2 . ASP B 1 52  ? 60.94621  -44.44565 4.11406   1.000 63.24308  ? 52  ASP B OD2 1 
ATOM   2937 N  N   . LEU B 1 53  ? 59.40497  -43.34991 0.63325   1.000 48.35372  ? 53  LEU B N   1 
ATOM   2938 C  CA  . LEU B 1 53  ? 60.08031  -42.24392 -0.03876  1.000 47.11512  ? 53  LEU B CA  1 
ATOM   2939 C  C   . LEU B 1 53  ? 59.08234  -41.19085 -0.51000  1.000 46.11681  ? 53  LEU B C   1 
ATOM   2940 O  O   . LEU B 1 53  ? 59.26062  -39.99240 -0.25973  1.000 42.28966  ? 53  LEU B O   1 
ATOM   2941 C  CB  . LEU B 1 53  ? 60.89683  -42.77981 -1.21366  1.000 46.37713  ? 53  LEU B CB  1 
ATOM   2942 C  CG  . LEU B 1 53  ? 61.65128  -41.74929 -2.05031  1.000 48.53760  ? 53  LEU B CG  1 
ATOM   2943 C  CD1 . LEU B 1 53  ? 62.62651  -40.98193 -1.17185  1.000 44.30079  ? 53  LEU B CD1 1 
ATOM   2944 C  CD2 . LEU B 1 53  ? 62.37452  -42.42851 -3.20995  1.000 40.85183  ? 53  LEU B CD2 1 
ATOM   2945 N  N   . ALA B 1 54  ? 58.01633  -41.62409 -1.18905  1.000 40.79851  ? 54  ALA B N   1 
ATOM   2946 C  CA  . ALA B 1 54  ? 57.01071  -40.68145 -1.66962  1.000 43.34898  ? 54  ALA B CA  1 
ATOM   2947 C  C   . ALA B 1 54  ? 56.35979  -39.92057 -0.51817  1.000 48.29530  ? 54  ALA B C   1 
ATOM   2948 O  O   . ALA B 1 54  ? 56.07629  -38.72272 -0.63834  1.000 48.49123  ? 54  ALA B O   1 
ATOM   2949 C  CB  . ALA B 1 54  ? 55.95678  -41.41881 -2.49212  1.000 40.43130  ? 54  ALA B CB  1 
ATOM   2950 N  N   . SER B 1 55  ? 56.12302  -40.59417 0.61057   1.000 44.78970  ? 55  SER B N   1 
ATOM   2951 C  CA  . SER B 1 55  ? 55.48979  -39.93454 1.74738   1.000 48.76555  ? 55  SER B CA  1 
ATOM   2952 C  C   . SER B 1 55  ? 56.39027  -38.88205 2.38395   1.000 48.91014  ? 55  SER B C   1 
ATOM   2953 O  O   . SER B 1 55  ? 55.88320  -37.96327 3.03640   1.000 47.15777  ? 55  SER B O   1 
ATOM   2954 C  CB  . SER B 1 55  ? 55.07780  -40.96957 2.79413   1.000 44.06417  ? 55  SER B CB  1 
ATOM   2955 O  OG  . SER B 1 55  ? 56.21347  -41.51245 3.44193   1.000 49.39730  ? 55  SER B OG  1 
ATOM   2956 N  N   . ARG B 1 56  ? 57.70663  -38.98999 2.20754   1.000 44.07014  ? 56  ARG B N   1 
ATOM   2957 C  CA  . ARG B 1 56  ? 58.62763  -37.99065 2.73227   1.000 42.61332  ? 56  ARG B CA  1 
ATOM   2958 C  C   . ARG B 1 56  ? 58.93536  -36.89236 1.72444   1.000 47.27042  ? 56  ARG B C   1 
ATOM   2959 O  O   . ARG B 1 56  ? 59.20286  -35.75357 2.12468   1.000 46.86986  ? 56  ARG B O   1 
ATOM   2960 C  CB  . ARG B 1 56  ? 59.92099  -38.66576 3.19225   1.000 46.31167  ? 56  ARG B CB  1 
ATOM   2961 C  CG  . ARG B 1 56  ? 59.69374  -39.67410 4.30248   1.000 45.59423  ? 56  ARG B CG  1 
ATOM   2962 C  CD  . ARG B 1 56  ? 60.96263  -40.39993 4.68848   1.000 52.52320  ? 56  ARG B CD  1 
ATOM   2963 N  NE  . ARG B 1 56  ? 60.68106  -41.44528 5.66299   1.000 56.74221  ? 56  ARG B NE  1 
ATOM   2964 C  CZ  . ARG B 1 56  ? 60.55870  -41.23669 6.96626   1.000 60.32535  ? 56  ARG B CZ  1 
ATOM   2965 N  NH1 . ARG B 1 56  ? 60.71100  -40.03137 7.49074   1.000 53.44093  ? 56  ARG B NH1 1 
ATOM   2966 N  NH2 . ARG B 1 56  ? 60.27111  -42.26158 7.76244   1.000 62.46565  ? 56  ARG B NH2 1 
ATOM   2967 N  N   . PHE B 1 57  ? 58.90203  -37.20611 0.42657   1.000 45.22750  ? 57  PHE B N   1 
ATOM   2968 C  CA  . PHE B 1 57  ? 58.95388  -36.15712 -0.58490  1.000 44.65911  ? 57  PHE B CA  1 
ATOM   2969 C  C   . PHE B 1 57  ? 57.69746  -35.29757 -0.56293  1.000 51.08900  ? 57  PHE B C   1 
ATOM   2970 O  O   . PHE B 1 57  ? 57.76539  -34.09181 -0.82935  1.000 49.59166  ? 57  PHE B O   1 
ATOM   2971 C  CB  . PHE B 1 57  ? 59.13054  -36.76521 -1.97774  1.000 43.06219  ? 57  PHE B CB  1 
ATOM   2972 C  CG  . PHE B 1 57  ? 60.53763  -37.18579 -2.28973  1.000 42.49229  ? 57  PHE B CG  1 
ATOM   2973 C  CD1 . PHE B 1 57  ? 61.60638  -36.67237 -1.57514  1.000 43.09442  ? 57  PHE B CD1 1 
ATOM   2974 C  CD2 . PHE B 1 57  ? 60.79113  -38.09059 -3.30960  1.000 44.38180  ? 57  PHE B CD2 1 
ATOM   2975 C  CE1 . PHE B 1 57  ? 62.90208  -37.05632 -1.86781  1.000 42.63470  ? 57  PHE B CE1 1 
ATOM   2976 C  CE2 . PHE B 1 57  ? 62.08560  -38.47715 -3.61105  1.000 39.26450  ? 57  PHE B CE2 1 
ATOM   2977 C  CZ  . PHE B 1 57  ? 63.14268  -37.95882 -2.88825  1.000 45.03345  ? 57  PHE B CZ  1 
ATOM   2978 N  N   . TYR B 1 58  ? 56.54787  -35.89420 -0.25829  1.000 45.40462  ? 58  TYR B N   1 
ATOM   2979 C  CA  . TYR B 1 58  ? 55.25366  -35.22018 -0.36603  1.000 48.42269  ? 58  TYR B CA  1 
ATOM   2980 C  C   . TYR B 1 58  ? 54.46295  -35.38514 0.92672   1.000 50.87954  ? 58  TYR B C   1 
ATOM   2981 O  O   . TYR B 1 58  ? 53.40446  -36.01936 0.94873   1.000 53.83455  ? 58  TYR B O   1 
ATOM   2982 C  CB  . TYR B 1 58  ? 54.47291  -35.76598 -1.56043  1.000 45.96487  ? 58  TYR B CB  1 
ATOM   2983 C  CG  . TYR B 1 58  ? 55.31607  -35.96070 -2.80330  1.000 48.67919  ? 58  TYR B CG  1 
ATOM   2984 C  CD1 . TYR B 1 58  ? 55.93180  -34.88007 -3.42261  1.000 48.70531  ? 58  TYR B CD1 1 
ATOM   2985 C  CD2 . TYR B 1 58  ? 55.49063  -37.22324 -3.36347  1.000 45.51187  ? 58  TYR B CD2 1 
ATOM   2986 C  CE1 . TYR B 1 58  ? 56.70349  -35.04926 -4.55714  1.000 48.81987  ? 58  TYR B CE1 1 
ATOM   2987 C  CE2 . TYR B 1 58  ? 56.26207  -37.40040 -4.50449  1.000 43.20390  ? 58  TYR B CE2 1 
ATOM   2988 C  CZ  . TYR B 1 58  ? 56.86523  -36.30775 -5.09467  1.000 47.14991  ? 58  TYR B CZ  1 
ATOM   2989 O  OH  . TYR B 1 58  ? 57.63157  -36.46416 -6.22547  1.000 41.86369  ? 58  TYR B OH  1 
ATOM   2990 N  N   . PRO B 1 59  ? 54.94582  -34.80900 2.03178   1.000 51.38307  ? 59  PRO B N   1 
ATOM   2991 C  CA  . PRO B 1 59  ? 54.20735  -34.93603 3.29693   1.000 54.47282  ? 59  PRO B CA  1 
ATOM   2992 C  C   . PRO B 1 59  ? 52.87917  -34.20877 3.28459   1.000 56.01374  ? 59  PRO B C   1 
ATOM   2993 O  O   . PRO B 1 59  ? 51.99646  -34.54556 4.08237   1.000 56.60228  ? 59  PRO B O   1 
ATOM   2994 C  CB  . PRO B 1 59  ? 55.16677  -34.32453 4.32309   1.000 50.53591  ? 59  PRO B CB  1 
ATOM   2995 C  CG  . PRO B 1 59  ? 55.92360  -33.30778 3.53647   1.000 51.72421  ? 59  PRO B CG  1 
ATOM   2996 C  CD  . PRO B 1 59  ? 56.09361  -33.89153 2.15503   1.000 51.01746  ? 59  PRO B CD  1 
ATOM   2997 N  N   . HIS B 1 60  ? 52.71360  -33.23048 2.39946   1.000 52.40945  ? 60  HIS B N   1 
ATOM   2998 C  CA  . HIS B 1 60  ? 51.49877  -32.43854 2.27754   1.000 52.72068  ? 60  HIS B CA  1 
ATOM   2999 C  C   . HIS B 1 60  ? 50.42764  -33.11073 1.43104   1.000 54.86370  ? 60  HIS B C   1 
ATOM   3000 O  O   . HIS B 1 60  ? 49.37013  -32.50984 1.21425   1.000 57.03922  ? 60  HIS B O   1 
ATOM   3001 C  CB  . HIS B 1 60  ? 51.83956  -31.07846 1.66857   1.000 53.86037  ? 60  HIS B CB  1 
ATOM   3002 C  CG  . HIS B 1 60  ? 52.51541  -31.17456 0.33570   1.000 55.17297  ? 60  HIS B CG  1 
ATOM   3003 N  ND1 . HIS B 1 60  ? 53.78589  -31.68696 0.18038   1.000 49.89203  ? 60  HIS B ND1 1 
ATOM   3004 C  CD2 . HIS B 1 60  ? 52.09360  -30.83458 -0.90503  1.000 52.27206  ? 60  HIS B CD2 1 
ATOM   3005 C  CE1 . HIS B 1 60  ? 54.11927  -31.65385 -1.09742  1.000 47.69739  ? 60  HIS B CE1 1 
ATOM   3006 N  NE2 . HIS B 1 60  ? 53.11030  -31.14004 -1.77758  1.000 51.83070  ? 60  HIS B NE2 1 
ATOM   3007 N  N   . ALA B 1 61  ? 50.67156  -34.32262 0.94201   1.000 54.13603  ? 61  ALA B N   1 
ATOM   3008 C  CA  . ALA B 1 61  ? 49.76032  -35.00250 0.03432   1.000 54.99791  ? 61  ALA B CA  1 
ATOM   3009 C  C   . ALA B 1 61  ? 49.12791  -36.20588 0.71849   1.000 51.08022  ? 61  ALA B C   1 
ATOM   3010 O  O   . ALA B 1 61  ? 49.78786  -36.91632 1.48384   1.000 52.02749  ? 61  ALA B O   1 
ATOM   3011 C  CB  . ALA B 1 61  ? 50.48668  -35.44991 -1.23811  1.000 54.02045  ? 61  ALA B CB  1 
ATOM   3012 N  N   . THR B 1 62  ? 47.84315  -36.42370 0.43957   1.000 56.25571  ? 62  THR B N   1 
ATOM   3013 C  CA  . THR B 1 62  ? 47.10903  -37.58033 0.93267   1.000 58.23237  ? 62  THR B CA  1 
ATOM   3014 C  C   . THR B 1 62  ? 46.25928  -38.14004 -0.19979  1.000 59.53762  ? 62  THR B C   1 
ATOM   3015 O  O   . THR B 1 62  ? 46.06185  -37.49616 -1.23402  1.000 57.61188  ? 62  THR B O   1 
ATOM   3016 C  CB  . THR B 1 62  ? 46.21062  -37.22861 2.12828   1.000 60.76585  ? 62  THR B CB  1 
ATOM   3017 O  OG1 . THR B 1 62  ? 45.25894  -36.23196 1.73268   1.000 62.12894  ? 62  THR B OG1 1 
ATOM   3018 C  CG2 . THR B 1 62  ? 47.03236  -36.70904 3.30460   1.000 50.87918  ? 62  THR B CG2 1 
ATOM   3019 N  N   . GLY B 1 63  ? 45.75315  -39.35345 0.00838   1.000 54.68086  ? 63  GLY B N   1 
ATOM   3020 C  CA  . GLY B 1 63  ? 44.82583  -39.94644 -0.94064  1.000 54.40216  ? 63  GLY B CA  1 
ATOM   3021 C  C   . GLY B 1 63  ? 45.42754  -40.10346 -2.32159  1.000 59.21024  ? 63  GLY B C   1 
ATOM   3022 O  O   . GLY B 1 63  ? 46.56436  -40.55960 -2.48748  1.000 58.90579  ? 63  GLY B O   1 
ATOM   3023 N  N   . ALA B 1 64  ? 44.64832  -39.71214 -3.33438  1.000 56.77776  ? 64  ALA B N   1 
ATOM   3024 C  CA  . ALA B 1 64  ? 45.07954  -39.87775 -4.71834  1.000 59.30593  ? 64  ALA B CA  1 
ATOM   3025 C  C   . ALA B 1 64  ? 46.31455  -39.04505 -5.03188  1.000 59.45181  ? 64  ALA B C   1 
ATOM   3026 O  O   . ALA B 1 64  ? 47.15983  -39.46932 -5.82885  1.000 60.80857  ? 64  ALA B O   1 
ATOM   3027 C  CB  . ALA B 1 64  ? 43.94071  -39.51291 -5.67070  1.000 51.99443  ? 64  ALA B CB  1 
ATOM   3028 N  N   . ASP B 1 65  ? 46.43644  -37.86283 -4.42263  1.000 59.52138  ? 65  ASP B N   1 
ATOM   3029 C  CA  . ASP B 1 65  ? 47.61304  -37.02893 -4.65017  1.000 59.32356  ? 65  ASP B CA  1 
ATOM   3030 C  C   . ASP B 1 65  ? 48.88160  -37.74413 -4.20533  1.000 56.26462  ? 65  ASP B C   1 
ATOM   3031 O  O   . ASP B 1 65  ? 49.89388  -37.73837 -4.91522  1.000 53.78164  ? 65  ASP B O   1 
ATOM   3032 C  CB  . ASP B 1 65  ? 47.46283  -35.69424 -3.92156  1.000 58.26705  ? 65  ASP B CB  1 
ATOM   3033 C  CG  . ASP B 1 65  ? 46.39870  -34.81003 -4.54019  1.000 63.58820  ? 65  ASP B CG  1 
ATOM   3034 O  OD1 . ASP B 1 65  ? 46.17999  -34.90485 -5.76863  1.000 60.47206  ? 65  ASP B OD1 1 
ATOM   3035 O  OD2 . ASP B 1 65  ? 45.78597  -34.01483 -3.79707  1.000 66.72546  ? 65  ASP B OD2 1 
ATOM   3036 N  N   . LEU B 1 66  ? 48.84241  -38.37433 -3.02938  1.000 54.04985  ? 66  LEU B N   1 
ATOM   3037 C  CA  . LEU B 1 66  ? 49.99041  -39.14972 -2.57302  1.000 52.66157  ? 66  LEU B CA  1 
ATOM   3038 C  C   . LEU B 1 66  ? 50.20170  -40.38660 -3.43904  1.000 55.84719  ? 66  LEU B C   1 
ATOM   3039 O  O   . LEU B 1 66  ? 51.34557  -40.78081 -3.69680  1.000 54.22110  ? 66  LEU B O   1 
ATOM   3040 C  CB  . LEU B 1 66  ? 49.80795  -39.54087 -1.10749  1.000 50.02576  ? 66  LEU B CB  1 
ATOM   3041 C  CG  . LEU B 1 66  ? 50.95739  -40.32573 -0.47287  1.000 53.73808  ? 66  LEU B CG  1 
ATOM   3042 C  CD1 . LEU B 1 66  ? 52.27060  -39.57573 -0.64598  1.000 45.46135  ? 66  LEU B CD1 1 
ATOM   3043 C  CD2 . LEU B 1 66  ? 50.67524  -40.59466 0.99747   1.000 49.89750  ? 66  LEU B CD2 1 
ATOM   3044 N  N   . ASP B 1 67  ? 49.11065  -41.00960 -3.89780  1.000 53.71605  ? 67  ASP B N   1 
ATOM   3045 C  CA  . ASP B 1 67  ? 49.22669  -42.18971 -4.75121  1.000 50.71775  ? 67  ASP B CA  1 
ATOM   3046 C  C   . ASP B 1 67  ? 50.00502  -41.88015 -6.02335  1.000 52.17342  ? 67  ASP B C   1 
ATOM   3047 O  O   . ASP B 1 67  ? 50.82229  -42.69221 -6.47333  1.000 52.31464  ? 67  ASP B O   1 
ATOM   3048 C  CB  . ASP B 1 67  ? 47.83828  -42.72931 -5.09606  1.000 54.73775  ? 67  ASP B CB  1 
ATOM   3049 C  CG  . ASP B 1 67  ? 47.24347  -43.56730 -3.98261  1.000 57.17304  ? 67  ASP B CG  1 
ATOM   3050 O  OD1 . ASP B 1 67  ? 47.91143  -43.74243 -2.94145  1.000 58.87541  ? 67  ASP B OD1 1 
ATOM   3051 O  OD2 . ASP B 1 67  ? 46.10763  -44.05771 -4.15339  1.000 63.35900  ? 67  ASP B OD2 1 
ATOM   3052 N  N   . LEU B 1 68  ? 49.75825  -40.71194 -6.62094  1.000 45.08966  ? 68  LEU B N   1 
ATOM   3053 C  CA  . LEU B 1 68  ? 50.51389  -40.30769 -7.80126  1.000 49.27633  ? 68  LEU B CA  1 
ATOM   3054 C  C   . LEU B 1 68  ? 52.00007  -40.18394 -7.48522  1.000 49.10236  ? 68  LEU B C   1 
ATOM   3055 O  O   . LEU B 1 68  ? 52.85025  -40.53165 -8.31296  1.000 48.21641  ? 68  LEU B O   1 
ATOM   3056 C  CB  . LEU B 1 68  ? 49.95736  -38.99131 -8.34385  1.000 45.60870  ? 68  LEU B CB  1 
ATOM   3057 C  CG  . LEU B 1 68  ? 50.68465  -38.31651 -9.50689  1.000 47.04169  ? 68  LEU B CG  1 
ATOM   3058 C  CD1 . LEU B 1 68  ? 50.68637  -39.20241 -10.74477 1.000 47.97232  ? 68  LEU B CD1 1 
ATOM   3059 C  CD2 . LEU B 1 68  ? 50.04791  -36.96610 -9.80418  1.000 48.49280  ? 68  LEU B CD2 1 
ATOM   3060 N  N   . GLY B 1 69  ? 52.33218  -39.70271 -6.28587  1.000 48.13077  ? 69  GLY B N   1 
ATOM   3061 C  CA  . GLY B 1 69  ? 53.72745  -39.65565 -5.87986  1.000 43.80180  ? 69  GLY B CA  1 
ATOM   3062 C  C   . GLY B 1 69  ? 54.31799  -41.03565 -5.66557  1.000 47.08545  ? 69  GLY B C   1 
ATOM   3063 O  O   . GLY B 1 69  ? 55.48064  -41.28240 -6.00046  1.000 47.55433  ? 69  GLY B O   1 
ATOM   3064 N  N   . VAL B 1 70  ? 53.52818  -41.95302 -5.10323  1.000 45.74727  ? 70  VAL B N   1 
ATOM   3065 C  CA  . VAL B 1 70  ? 53.97588  -43.33593 -4.96520  1.000 47.69931  ? 70  VAL B CA  1 
ATOM   3066 C  C   . VAL B 1 70  ? 54.19865  -43.95883 -6.33666  1.000 44.56974  ? 70  VAL B C   1 
ATOM   3067 O  O   . VAL B 1 70  ? 55.18302  -44.67565 -6.55800  1.000 44.87322  ? 70  VAL B O   1 
ATOM   3068 C  CB  . VAL B 1 70  ? 52.96346  -44.14543 -4.13227  1.000 47.08692  ? 70  VAL B CB  1 
ATOM   3069 C  CG1 . VAL B 1 70  ? 53.36348  -45.61061 -4.07748  1.000 43.03765  ? 70  VAL B CG1 1 
ATOM   3070 C  CG2 . VAL B 1 70  ? 52.85064  -43.57078 -2.72860  1.000 45.79180  ? 70  VAL B CG2 1 
ATOM   3071 N  N   . ASP B 1 71  ? 53.29500  -43.68545 -7.28169  1.000 41.47220  ? 71  ASP B N   1 
ATOM   3072 C  CA  . ASP B 1 71  ? 53.41580  -44.26613 -8.61519  1.000 47.04996  ? 71  ASP B CA  1 
ATOM   3073 C  C   . ASP B 1 71  ? 54.64780  -43.74082 -9.34018  1.000 48.49624  ? 71  ASP B C   1 
ATOM   3074 O  O   . ASP B 1 71  ? 55.33190  -44.49998 -10.03713 1.000 49.84742  ? 71  ASP B O   1 
ATOM   3075 C  CB  . ASP B 1 71  ? 52.15178  -43.98542 -9.43043  1.000 48.50741  ? 71  ASP B CB  1 
ATOM   3076 C  CG  . ASP B 1 71  ? 50.95686  -44.78716 -8.94829  1.000 52.86853  ? 71  ASP B CG  1 
ATOM   3077 O  OD1 . ASP B 1 71  ? 51.15320  -45.70931 -8.12885  1.000 48.20588  ? 71  ASP B OD1 1 
ATOM   3078 O  OD2 . ASP B 1 71  ? 49.82299  -44.49541 -9.38513  1.000 49.61339  ? 71  ASP B OD2 1 
ATOM   3079 N  N   . LEU B 1 72  ? 54.94866  -42.44795 -9.18887  1.000 45.05563  ? 72  LEU B N   1 
ATOM   3080 C  CA  . LEU B 1 72  ? 56.13957  -41.89276 -9.82387  1.000 49.83824  ? 72  LEU B CA  1 
ATOM   3081 C  C   . LEU B 1 72  ? 57.40116  -42.56849 -9.30172  1.000 45.03421  ? 72  LEU B C   1 
ATOM   3082 O  O   . LEU B 1 72  ? 58.28719  -42.93948 -10.08010 1.000 47.01858  ? 72  LEU B O   1 
ATOM   3083 C  CB  . LEU B 1 72  ? 56.20990  -40.38175 -9.60330  1.000 44.63900  ? 72  LEU B CB  1 
ATOM   3084 C  CG  . LEU B 1 72  ? 57.46870  -39.74544 -10.20122 1.000 45.66121  ? 72  LEU B CG  1 
ATOM   3085 C  CD1 . LEU B 1 72  ? 57.53722  -40.01083 -11.70012 1.000 42.53480  ? 72  LEU B CD1 1 
ATOM   3086 C  CD2 . LEU B 1 72  ? 57.54307  -38.25325 -9.91100  1.000 49.70104  ? 72  LEU B CD2 1 
ATOM   3087 N  N   . MET B 1 73  ? 57.49801  -42.74071 -7.98149  1.000 41.80052  ? 73  MET B N   1 
ATOM   3088 C  CA  . MET B 1 73  ? 58.64818  -43.43490 -7.41105  1.000 43.84751  ? 73  MET B CA  1 
ATOM   3089 C  C   . MET B 1 73  ? 58.71379  -44.87331 -7.90705  1.000 48.10346  ? 73  MET B C   1 
ATOM   3090 O  O   . MET B 1 73  ? 59.76274  -45.33330 -8.37204  1.000 44.01394  ? 73  MET B O   1 
ATOM   3091 C  CB  . MET B 1 73  ? 58.58990  -43.39438 -5.88290  1.000 42.97824  ? 73  MET B CB  1 
ATOM   3092 C  CG  . MET B 1 73  ? 58.62845  -41.99486 -5.28437  1.000 47.04460  ? 73  MET B CG  1 
ATOM   3093 S  SD  . MET B 1 73  ? 60.09131  -41.06116 -5.77509  1.000 46.24813  ? 73  MET B SD  1 
ATOM   3094 C  CE  . MET B 1 73  ? 59.39190  -39.89867 -6.94495  1.000 42.90912  ? 73  MET B CE  1 
ATOM   3095 N  N   . SER B 1 74  ? 57.59492  -45.59859 -7.81541  1.000 45.46054  ? 74  SER B N   1 
ATOM   3096 C  CA  . SER B 1 74  ? 57.53801  -46.96316 -8.33162  1.000 43.45121  ? 74  SER B CA  1 
ATOM   3097 C  C   . SER B 1 74  ? 57.98714  -47.01858 -9.78297  1.000 42.77512  ? 74  SER B C   1 
ATOM   3098 O  O   . SER B 1 74  ? 58.83072  -47.84132 -10.15667 1.000 45.69358  ? 74  SER B O   1 
ATOM   3099 C  CB  . SER B 1 74  ? 56.11865  -47.51923 -8.20205  1.000 45.51092  ? 74  SER B CB  1 
ATOM   3100 O  OG  . SER B 1 74  ? 55.76000  -47.70689 -6.84788  1.000 42.78411  ? 74  SER B OG  1 
ATOM   3101 N  N   . TRP B 1 75  ? 57.43588  -46.13520 -10.61549 1.000 44.14808  ? 75  TRP B N   1 
ATOM   3102 C  CA  . TRP B 1 75  ? 57.76149  -46.16108 -12.03598 1.000 43.65248  ? 75  TRP B CA  1 
ATOM   3103 C  C   . TRP B 1 75  ? 59.22448  -45.81660 -12.28003 1.000 44.80904  ? 75  TRP B C   1 
ATOM   3104 O  O   . TRP B 1 75  ? 59.87911  -46.43737 -13.12510 1.000 44.98764  ? 75  TRP B O   1 
ATOM   3105 C  CB  . TRP B 1 75  ? 56.85766  -45.19914 -12.80396 1.000 43.24049  ? 75  TRP B CB  1 
ATOM   3106 C  CG  . TRP B 1 75  ? 57.17732  -45.15385 -14.26504 1.000 46.61401  ? 75  TRP B CG  1 
ATOM   3107 C  CD1 . TRP B 1 75  ? 56.61231  -45.90790 -15.24957 1.000 45.57992  ? 75  TRP B CD1 1 
ATOM   3108 C  CD2 . TRP B 1 75  ? 58.15314  -44.32353 -14.90519 1.000 44.34075  ? 75  TRP B CD2 1 
ATOM   3109 N  NE1 . TRP B 1 75  ? 57.17155  -45.59593 -16.46385 1.000 44.49735  ? 75  TRP B NE1 1 
ATOM   3110 C  CE2 . TRP B 1 75  ? 58.12085  -44.62603 -16.27915 1.000 46.63377  ? 75  TRP B CE2 1 
ATOM   3111 C  CE3 . TRP B 1 75  ? 59.04898  -43.35152 -14.45005 1.000 45.97565  ? 75  TRP B CE3 1 
ATOM   3112 C  CZ2 . TRP B 1 75  ? 58.94967  -43.99359 -17.20093 1.000 44.76934  ? 75  TRP B CZ2 1 
ATOM   3113 C  CZ3 . TRP B 1 75  ? 59.87140  -42.72530 -15.36837 1.000 41.59477  ? 75  TRP B CZ3 1 
ATOM   3114 C  CH2 . TRP B 1 75  ? 59.81499  -43.04773 -16.72609 1.000 44.11749  ? 75  TRP B CH2 1 
ATOM   3115 N  N   . ALA B 1 76  ? 59.75150  -44.82231 -11.55845 1.000 40.70942  ? 76  ALA B N   1 
ATOM   3116 C  CA  . ALA B 1 76  ? 61.11793  -44.36709 -11.80501 1.000 43.69969  ? 76  ALA B CA  1 
ATOM   3117 C  C   . ALA B 1 76  ? 62.12662  -45.47891 -11.55975 1.000 45.20616  ? 76  ALA B C   1 
ATOM   3118 O  O   . ALA B 1 76  ? 63.08471  -45.63907 -12.32559 1.000 48.37502  ? 76  ALA B O   1 
ATOM   3119 C  CB  . ALA B 1 76  ? 61.43971  -43.15536 -10.92961 1.000 43.99309  ? 76  ALA B CB  1 
ATOM   3120 N  N   . PHE B 1 77  ? 61.92551  -46.26386 -10.50199 1.000 41.81371  ? 77  PHE B N   1 
ATOM   3121 C  CA  . PHE B 1 77  ? 62.86453  -47.33504 -10.19950 1.000 41.09423  ? 77  PHE B CA  1 
ATOM   3122 C  C   . PHE B 1 77  ? 62.64903  -48.55870 -11.08016 1.000 46.64832  ? 77  PHE B C   1 
ATOM   3123 O  O   . PHE B 1 77  ? 63.62075  -49.24232 -11.42159 1.000 42.96210  ? 77  PHE B O   1 
ATOM   3124 C  CB  . PHE B 1 77  ? 62.77349  -47.70344 -8.72054  1.000 42.17419  ? 77  PHE B CB  1 
ATOM   3125 C  CG  . PHE B 1 77  ? 63.41016  -46.68824 -7.81565  1.000 47.12493  ? 77  PHE B CG  1 
ATOM   3126 C  CD1 . PHE B 1 77  ? 64.75217  -46.78116 -7.48446  1.000 43.03862  ? 77  PHE B CD1 1 
ATOM   3127 C  CD2 . PHE B 1 77  ? 62.67527  -45.62554 -7.31866  1.000 45.81346  ? 77  PHE B CD2 1 
ATOM   3128 C  CE1 . PHE B 1 77  ? 65.34496  -45.84104 -6.66333  1.000 48.86517  ? 77  PHE B CE1 1 
ATOM   3129 C  CE2 . PHE B 1 77  ? 63.26223  -44.68261 -6.49441  1.000 51.82789  ? 77  PHE B CE2 1 
ATOM   3130 C  CZ  . PHE B 1 77  ? 64.59923  -44.79144 -6.16742  1.000 51.74347  ? 77  PHE B CZ  1 
ATOM   3131 N  N   . LEU B 1 78  ? 61.40200  -48.85204 -11.46005 1.000 39.26847  ? 78  LEU B N   1 
ATOM   3132 C  CA  . LEU B 1 78  ? 61.17337  -49.90702 -12.44170 1.000 45.17215  ? 78  LEU B CA  1 
ATOM   3133 C  C   . LEU B 1 78  ? 61.72555  -49.50478 -13.80233 1.000 42.76580  ? 78  LEU B C   1 
ATOM   3134 O  O   . LEU B 1 78  ? 62.25826  -50.34470 -14.53721 1.000 40.53367  ? 78  LEU B O   1 
ATOM   3135 C  CB  . LEU B 1 78  ? 59.68191  -50.23036 -12.53474 1.000 39.79195  ? 78  LEU B CB  1 
ATOM   3136 C  CG  . LEU B 1 78  ? 59.06006  -50.91162 -11.31114 1.000 46.18468  ? 78  LEU B CG  1 
ATOM   3137 C  CD1 . LEU B 1 78  ? 57.53883  -50.83955 -11.36070 1.000 40.05957  ? 78  LEU B CD1 1 
ATOM   3138 C  CD2 . LEU B 1 78  ? 59.52747  -52.35629 -11.21275 1.000 41.30700  ? 78  LEU B CD2 1 
ATOM   3139 N  N   . PHE B 1 79  ? 61.61190  -48.22035 -14.14813 1.000 42.64336  ? 79  PHE B N   1 
ATOM   3140 C  CA  . PHE B 1 79  ? 62.20675  -47.72036 -15.38404 1.000 44.81188  ? 79  PHE B CA  1 
ATOM   3141 C  C   . PHE B 1 79  ? 63.72198  -47.87107 -15.35901 1.000 47.65996  ? 79  PHE B C   1 
ATOM   3142 O  O   . PHE B 1 79  ? 64.33208  -48.30790 -16.34180 1.000 47.29680  ? 79  PHE B O   1 
ATOM   3143 C  CB  . PHE B 1 79  ? 61.81171  -46.25713 -15.59218 1.000 42.16295  ? 79  PHE B CB  1 
ATOM   3144 C  CG  . PHE B 1 79  ? 62.43321  -45.61598 -16.80451 1.000 47.29300  ? 79  PHE B CG  1 
ATOM   3145 C  CD1 . PHE B 1 79  ? 61.98668  -45.92792 -18.07945 1.000 44.50765  ? 79  PHE B CD1 1 
ATOM   3146 C  CD2 . PHE B 1 79  ? 63.44524  -44.67761 -16.66609 1.000 47.94985  ? 79  PHE B CD2 1 
ATOM   3147 C  CE1 . PHE B 1 79  ? 62.54811  -45.32599 -19.19577 1.000 49.49610  ? 79  PHE B CE1 1 
ATOM   3148 C  CE2 . PHE B 1 79  ? 64.01191  -44.07365 -17.77846 1.000 49.06865  ? 79  PHE B CE2 1 
ATOM   3149 C  CZ  . PHE B 1 79  ? 63.56118  -44.39797 -19.04417 1.000 49.33686  ? 79  PHE B CZ  1 
ATOM   3150 N  N   . ASP B 1 80  ? 64.34546  -47.51905 -14.23097 1.000 48.13623  ? 80  ASP B N   1 
ATOM   3151 C  CA  . ASP B 1 80  ? 65.79852  -47.59457 -14.12274 1.000 47.42090  ? 80  ASP B CA  1 
ATOM   3152 C  C   . ASP B 1 80  ? 66.29776  -49.02945 -14.23110 1.000 48.93255  ? 80  ASP B C   1 
ATOM   3153 O  O   . ASP B 1 80  ? 67.40630  -49.26107 -14.72874 1.000 48.35005  ? 80  ASP B O   1 
ATOM   3154 C  CB  . ASP B 1 80  ? 66.25484  -46.96836 -12.80300 1.000 47.27148  ? 80  ASP B CB  1 
ATOM   3155 C  CG  . ASP B 1 80  ? 67.75445  -46.74689 -12.74771 1.000 54.67832  ? 80  ASP B CG  1 
ATOM   3156 O  OD1 . ASP B 1 80  ? 68.26468  -45.93833 -13.55185 1.000 55.89453  ? 80  ASP B OD1 1 
ATOM   3157 O  OD2 . ASP B 1 80  ? 68.42198  -47.37744 -11.90008 1.000 48.81743  ? 80  ASP B OD2 1 
ATOM   3158 N  N   . ASP B 1 81  ? 65.49657  -50.00089 -13.77451 1.000 44.73674  ? 81  ASP B N   1 
ATOM   3159 C  CA  . ASP B 1 81  ? 65.86112  -51.41046 -13.90268 1.000 43.64860  ? 81  ASP B CA  1 
ATOM   3160 C  C   . ASP B 1 81  ? 66.17669  -51.79254 -15.34049 1.000 47.15323  ? 81  ASP B C   1 
ATOM   3161 O  O   . ASP B 1 81  ? 67.03651  -52.64617 -15.58300 1.000 47.42314  ? 81  ASP B O   1 
ATOM   3162 C  CB  . ASP B 1 81  ? 64.72841  -52.30154 -13.38749 1.000 52.04952  ? 81  ASP B CB  1 
ATOM   3163 C  CG  . ASP B 1 81  ? 64.73563  -52.45051 -11.87887 1.000 53.50110  ? 81  ASP B CG  1 
ATOM   3164 O  OD1 . ASP B 1 81  ? 65.71768  -52.01543 -11.24033 1.000 54.05490  ? 81  ASP B OD1 1 
ATOM   3165 O  OD2 . ASP B 1 81  ? 63.75718  -53.00923 -11.33332 1.000 52.27968  ? 81  ASP B OD2 1 
ATOM   3166 N  N   . LEU B 1 82  ? 65.49574  -51.17205 -16.30419 1.000 41.69968  ? 82  LEU B N   1 
ATOM   3167 C  CA  . LEU B 1 82  ? 65.59391  -51.57457 -17.69986 1.000 42.18128  ? 82  LEU B CA  1 
ATOM   3168 C  C   . LEU B 1 82  ? 66.92101  -51.19695 -18.34475 1.000 51.42974  ? 82  LEU B C   1 
ATOM   3169 O  O   . LEU B 1 82  ? 67.15438  -51.57341 -19.49840 1.000 48.42070  ? 82  LEU B O   1 
ATOM   3170 C  CB  . LEU B 1 82  ? 64.43627  -50.95789 -18.48401 1.000 44.80673  ? 82  LEU B CB  1 
ATOM   3171 C  CG  . LEU B 1 82  ? 63.05518  -51.35961 -17.95820 1.000 47.11312  ? 82  LEU B CG  1 
ATOM   3172 C  CD1 . LEU B 1 82  ? 61.95662  -50.54360 -18.61457 1.000 46.32725  ? 82  LEU B CD1 1 
ATOM   3173 C  CD2 . LEU B 1 82  ? 62.82407  -52.84591 -18.18019 1.000 46.24617  ? 82  LEU B CD2 1 
ATOM   3174 N  N   . PHE B 1 83  ? 67.79473  -50.48038 -17.63774 1.000 49.15397  ? 83  PHE B N   1 
ATOM   3175 C  CA  . PHE B 1 83  ? 69.05388  -50.01819 -18.20600 1.000 50.57997  ? 83  PHE B CA  1 
ATOM   3176 C  C   . PHE B 1 83  ? 70.26772  -50.54842 -17.45508 1.000 54.35415  ? 83  PHE B C   1 
ATOM   3177 O  O   . PHE B 1 83  ? 71.37722  -50.04223 -17.65981 1.000 56.16956  ? 83  PHE B O   1 
ATOM   3178 C  CB  . PHE B 1 83  ? 69.08260  -48.48690 -18.24667 1.000 46.57514  ? 83  PHE B CB  1 
ATOM   3179 C  CG  . PHE B 1 83  ? 67.94647  -47.88467 -19.02349 1.000 46.60582  ? 83  PHE B CG  1 
ATOM   3180 C  CD1 . PHE B 1 83  ? 68.04895  -47.68615 -20.39110 1.000 49.27471  ? 83  PHE B CD1 1 
ATOM   3181 C  CD2 . PHE B 1 83  ? 66.77068  -47.53077 -18.38718 1.000 47.51525  ? 83  PHE B CD2 1 
ATOM   3182 C  CE1 . PHE B 1 83  ? 66.99940  -47.13645 -21.10669 1.000 49.59916  ? 83  PHE B CE1 1 
ATOM   3183 C  CE2 . PHE B 1 83  ? 65.72111  -46.98437 -19.09371 1.000 49.10836  ? 83  PHE B CE2 1 
ATOM   3184 C  CZ  . PHE B 1 83  ? 65.83362  -46.78628 -20.45598 1.000 51.28975  ? 83  PHE B CZ  1 
ATOM   3185 N  N   . ASP B 1 84  ? 70.09140  -51.55391 -16.59589 1.000 53.97040  ? 84  ASP B N   1 
ATOM   3186 C  CA  . ASP B 1 84  ? 71.21047  -52.14393 -15.87234 1.000 58.73701  ? 84  ASP B CA  1 
ATOM   3187 C  C   . ASP B 1 84  ? 71.96698  -53.18059 -16.68947 1.000 61.52147  ? 84  ASP B C   1 
ATOM   3188 O  O   . ASP B 1 84  ? 73.07709  -53.55901 -16.30032 1.000 69.42601  ? 84  ASP B O   1 
ATOM   3189 C  CB  . ASP B 1 84  ? 70.72353  -52.78182 -14.56807 1.000 61.84187  ? 84  ASP B CB  1 
ATOM   3190 C  CG  . ASP B 1 84  ? 70.42205  -51.75429 -13.49307 1.000 69.78298  ? 84  ASP B CG  1 
ATOM   3191 O  OD1 . ASP B 1 84  ? 71.07257  -50.68706 -13.49144 1.000 73.18368  ? 84  ASP B OD1 1 
ATOM   3192 O  OD2 . ASP B 1 84  ? 69.53882  -52.01334 -12.64733 1.000 77.10327  ? 84  ASP B OD2 1 
ATOM   3193 N  N   . GLY B 1 85  ? 71.40386  -53.64353 -17.80153 1.000 62.76925  ? 85  GLY B N   1 
ATOM   3194 C  CA  . GLY B 1 85  ? 72.05728  -54.62512 -18.63073 1.000 55.53048  ? 85  GLY B CA  1 
ATOM   3195 C  C   . GLY B 1 85  ? 72.65161  -54.02103 -19.88542 1.000 56.53744  ? 85  GLY B C   1 
ATOM   3196 O  O   . GLY B 1 85  ? 73.14806  -52.88962 -19.88633 1.000 58.44365  ? 85  GLY B O   1 
ATOM   3197 N  N   . PRO B 1 86  ? 72.61125  -54.77423 -20.98698 1.000 56.79963  ? 86  PRO B N   1 
ATOM   3198 C  CA  . PRO B 1 86  ? 73.23431  -54.28502 -22.22823 1.000 59.41912  ? 86  PRO B CA  1 
ATOM   3199 C  C   . PRO B 1 86  ? 72.58724  -53.03065 -22.78898 1.000 57.21670  ? 86  PRO B C   1 
ATOM   3200 O  O   . PRO B 1 86  ? 73.27263  -52.24910 -23.46052 1.000 55.17229  ? 86  PRO B O   1 
ATOM   3201 C  CB  . PRO B 1 86  ? 73.08114  -55.47354 -23.18964 1.000 50.89162  ? 86  PRO B CB  1 
ATOM   3202 C  CG  . PRO B 1 86  ? 72.88901  -56.66080 -22.30650 1.000 57.02679  ? 86  PRO B CG  1 
ATOM   3203 C  CD  . PRO B 1 86  ? 72.13055  -56.15875 -21.11737 1.000 57.69590  ? 86  PRO B CD  1 
ATOM   3204 N  N   . ARG B 1 87  ? 71.29111  -52.81260 -22.54120 1.000 53.29378  ? 87  ARG B N   1 
ATOM   3205 C  CA  . ARG B 1 87  ? 70.62448  -51.63350 -23.08932 1.000 55.25680  ? 87  ARG B CA  1 
ATOM   3206 C  C   . ARG B 1 87  ? 71.27850  -50.34842 -22.59795 1.000 54.06379  ? 87  ARG B C   1 
ATOM   3207 O  O   . ARG B 1 87  ? 71.47969  -49.40807 -23.37569 1.000 54.89605  ? 87  ARG B O   1 
ATOM   3208 C  CB  . ARG B 1 87  ? 69.13798  -51.63993 -22.72867 1.000 51.96899  ? 87  ARG B CB  1 
ATOM   3209 C  CG  . ARG B 1 87  ? 68.41881  -50.35929 -23.13899 1.000 54.00061  ? 87  ARG B CG  1 
ATOM   3210 C  CD  . ARG B 1 87  ? 66.97040  -50.32987 -22.68222 1.000 54.61527  ? 87  ARG B CD  1 
ATOM   3211 N  NE  . ARG B 1 87  ? 66.14089  -51.27769 -23.41466 1.000 58.35281  ? 87  ARG B NE  1 
ATOM   3212 C  CZ  . ARG B 1 87  ? 65.70050  -52.42537 -22.91886 1.000 61.11492  ? 87  ARG B CZ  1 
ATOM   3213 N  NH1 . ARG B 1 87  ? 65.98632  -52.80006 -21.68242 1.000 50.28473  ? 87  ARG B NH1 1 
ATOM   3214 N  NH2 . ARG B 1 87  ? 64.94906  -53.21442 -23.68041 1.000 65.16605  ? 87  ARG B NH2 1 
ATOM   3215 N  N   . GLY B 1 88  ? 71.62337  -50.29129 -21.31311 1.000 52.00821  ? 88  GLY B N   1 
ATOM   3216 C  CA  . GLY B 1 88  ? 72.28421  -49.12814 -20.75618 1.000 49.37071  ? 88  GLY B CA  1 
ATOM   3217 C  C   . GLY B 1 88  ? 73.70175  -48.90331 -21.23242 1.000 56.68181  ? 88  GLY B C   1 
ATOM   3218 O  O   . GLY B 1 88  ? 74.30666  -47.89400 -20.85917 1.000 55.49339  ? 88  GLY B O   1 
ATOM   3219 N  N   . GLU B 1 89  ? 74.25219  -49.81184 -22.03854 1.000 50.48931  ? 89  GLU B N   1 
ATOM   3220 C  CA  . GLU B 1 89  ? 75.59194  -49.66195 -22.59101 1.000 57.07590  ? 89  GLU B CA  1 
ATOM   3221 C  C   . GLU B 1 89  ? 75.57716  -49.40510 -24.09255 1.000 51.91917  ? 89  GLU B C   1 
ATOM   3222 O  O   . GLU B 1 89  ? 76.63247  -49.45767 -24.73277 1.000 55.36136  ? 89  GLU B O   1 
ATOM   3223 C  CB  . GLU B 1 89  ? 76.43430  -50.89758 -22.27148 1.000 54.13426  ? 89  GLU B CB  1 
ATOM   3224 C  CG  . GLU B 1 89  ? 76.44458  -51.25193 -20.79177 1.000 70.20935  ? 89  GLU B CG  1 
ATOM   3225 C  CD  . GLU B 1 89  ? 77.61330  -52.13400 -20.41128 1.000 79.31393  ? 89  GLU B CD  1 
ATOM   3226 O  OE1 . GLU B 1 89  ? 78.50685  -52.33395 -21.26019 1.000 85.86447  ? 89  GLU B OE1 1 
ATOM   3227 O  OE2 . GLU B 1 89  ? 77.64140  -52.62415 -19.26284 1.000 91.00660  ? 89  GLU B OE2 1 
ATOM   3228 N  N   . ASN B 1 90  ? 74.40909  -49.13192 -24.66729 1.000 49.03105  ? 90  ASN B N   1 
ATOM   3229 C  CA  . ASN B 1 90  ? 74.28423  -48.79890 -26.07948 1.000 51.33757  ? 90  ASN B CA  1 
ATOM   3230 C  C   . ASN B 1 90  ? 73.30992  -47.63773 -26.22394 1.000 49.70618  ? 90  ASN B C   1 
ATOM   3231 O  O   . ASN B 1 90  ? 72.11591  -47.79012 -25.93594 1.000 50.52275  ? 90  ASN B O   1 
ATOM   3232 C  CB  . ASN B 1 90  ? 73.81033  -50.00770 -26.88921 1.000 52.70530  ? 90  ASN B CB  1 
ATOM   3233 C  CG  . ASN B 1 90  ? 73.75525  -49.72677 -28.38057 1.000 60.01455  ? 90  ASN B CG  1 
ATOM   3234 O  OD1 . ASN B 1 90  ? 72.80836  -49.11433 -28.87496 1.000 57.75945  ? 90  ASN B OD1 1 
ATOM   3235 N  ND2 . ASN B 1 90  ? 74.77328  -50.17843 -29.10621 1.000 60.56304  ? 90  ASN B ND2 1 
ATOM   3236 N  N   . PRO B 1 91  ? 73.77633  -46.46463 -26.65783 1.000 48.00034  ? 91  PRO B N   1 
ATOM   3237 C  CA  . PRO B 1 91  ? 72.86637  -45.31262 -26.74465 1.000 50.14049  ? 91  PRO B CA  1 
ATOM   3238 C  C   . PRO B 1 91  ? 71.75337  -45.50127 -27.75431 1.000 50.63474  ? 91  PRO B C   1 
ATOM   3239 O  O   . PRO B 1 91  ? 70.65112  -44.98008 -27.54541 1.000 48.54618  ? 91  PRO B O   1 
ATOM   3240 C  CB  . PRO B 1 91  ? 73.79731  -44.15784 -27.13528 1.000 50.65569  ? 91  PRO B CB  1 
ATOM   3241 C  CG  . PRO B 1 91  ? 74.97420  -44.82100 -27.78019 1.000 51.07845  ? 91  PRO B CG  1 
ATOM   3242 C  CD  . PRO B 1 91  ? 75.15014  -46.12377 -27.06217 1.000 47.56563  ? 91  PRO B CD  1 
ATOM   3243 N  N   . GLU B 1 92  ? 72.00308  -46.23144 -28.84149 1.000 51.21390  ? 92  GLU B N   1 
ATOM   3244 C  CA  . GLU B 1 92  ? 70.93998  -46.49914 -29.80326 1.000 54.85227  ? 92  GLU B CA  1 
ATOM   3245 C  C   . GLU B 1 92  ? 69.85259  -47.37249 -29.18638 1.000 49.85727  ? 92  GLU B C   1 
ATOM   3246 O  O   . GLU B 1 92  ? 68.65853  -47.12676 -29.39203 1.000 51.73435  ? 92  GLU B O   1 
ATOM   3247 C  CB  . GLU B 1 92  ? 71.52713  -47.15345 -31.05345 1.000 57.83285  ? 92  GLU B CB  1 
ATOM   3248 C  CG  . GLU B 1 92  ? 70.57129  -47.25732 -32.22483 1.000 73.74237  ? 92  GLU B CG  1 
ATOM   3249 C  CD  . GLU B 1 92  ? 71.25235  -47.78509 -33.47581 1.000 82.81306  ? 92  GLU B CD  1 
ATOM   3250 O  OE1 . GLU B 1 92  ? 72.45842  -48.10671 -33.40643 1.000 81.11296  ? 92  GLU B OE1 1 
ATOM   3251 O  OE2 . GLU B 1 92  ? 70.58570  -47.87650 -34.52811 1.000 79.60866  ? 92  GLU B OE2 1 
ATOM   3252 N  N   . ASP B 1 93  ? 70.24665  -48.38930 -28.41719 1.000 43.80203  ? 93  ASP B N   1 
ATOM   3253 C  CA  . ASP B 1 93  ? 69.26787  -49.21978 -27.72380 1.000 52.20498  ? 93  ASP B CA  1 
ATOM   3254 C  C   . ASP B 1 93  ? 68.55781  -48.43106 -26.63066 1.000 53.28564  ? 93  ASP B C   1 
ATOM   3255 O  O   . ASP B 1 93  ? 67.33242  -48.51831 -26.48590 1.000 50.60897  ? 93  ASP B O   1 
ATOM   3256 C  CB  . ASP B 1 93  ? 69.95158  -50.45529 -27.14073 1.000 54.58895  ? 93  ASP B CB  1 
ATOM   3257 C  CG  . ASP B 1 93  ? 70.47350  -51.38968 -28.21237 1.000 61.60556  ? 93  ASP B CG  1 
ATOM   3258 O  OD1 . ASP B 1 93  ? 70.19605  -51.14372 -29.40631 1.000 59.77029  ? 93  ASP B OD1 1 
ATOM   3259 O  OD2 . ASP B 1 93  ? 71.16022  -52.37123 -27.86053 1.000 62.37133  ? 93  ASP B OD2 1 
ATOM   3260 N  N   . THR B 1 94  ? 69.31629  -47.65931 -25.84526 1.000 49.95657  ? 94  THR B N   1 
ATOM   3261 C  CA  . THR B 1 94  ? 68.70966  -46.81754 -24.81807 1.000 43.10288  ? 94  THR B CA  1 
ATOM   3262 C  C   . THR B 1 94  ? 67.73073  -45.82660 -25.43496 1.000 45.94616  ? 94  THR B C   1 
ATOM   3263 O  O   . THR B 1 94  ? 66.59637  -45.68238 -24.96544 1.000 45.80243  ? 94  THR B O   1 
ATOM   3264 C  CB  . THR B 1 94  ? 69.79646  -46.08418 -24.02689 1.000 44.58505  ? 94  THR B CB  1 
ATOM   3265 O  OG1 . THR B 1 94  ? 70.47948  -47.01163 -23.17546 1.000 45.52007  ? 94  THR B OG1 1 
ATOM   3266 C  CG2 . THR B 1 94  ? 69.19439  -44.97746 -23.17518 1.000 42.53770  ? 94  THR B CG2 1 
ATOM   3267 N  N   . LYS B 1 95  ? 68.14540  -45.14817 -26.50819 1.000 48.07409  ? 95  LYS B N   1 
ATOM   3268 C  CA  . LYS B 1 95  ? 67.26459  -44.17017 -27.13690 1.000 48.70440  ? 95  LYS B CA  1 
ATOM   3269 C  C   . LYS B 1 95  ? 66.05535  -44.83205 -27.78572 1.000 48.44665  ? 95  LYS B C   1 
ATOM   3270 O  O   . LYS B 1 95  ? 65.00713  -44.19400 -27.92576 1.000 51.19002  ? 95  LYS B O   1 
ATOM   3271 C  CB  . LYS B 1 95  ? 68.03425  -43.34036 -28.16460 1.000 46.30190  ? 95  LYS B CB  1 
ATOM   3272 C  CG  . LYS B 1 95  ? 67.27458  -42.11136 -28.63714 1.000 52.83025  ? 95  LYS B CG  1 
ATOM   3273 C  CD  . LYS B 1 95  ? 68.14587  -41.19693 -29.48086 1.000 57.95916  ? 95  LYS B CD  1 
ATOM   3274 C  CE  . LYS B 1 95  ? 67.42023  -39.90083 -29.82166 1.000 52.62399  ? 95  LYS B CE  1 
ATOM   3275 N  NZ  . LYS B 1 95  ? 66.16619  -40.14915 -30.58219 1.000 60.27430  ? 95  LYS B NZ  1 
ATOM   3276 N  N   . GLN B 1 96  ? 66.17281  -46.10049 -28.18522 1.000 51.24269  ? 96  GLN B N   1 
ATOM   3277 C  CA  . GLN B 1 96  ? 65.01483  -46.80191 -28.73081 1.000 55.52892  ? 96  GLN B CA  1 
ATOM   3278 C  C   . GLN B 1 96  ? 63.90478  -46.91391 -27.69008 1.000 54.02741  ? 96  GLN B C   1 
ATOM   3279 O  O   . GLN B 1 96  ? 62.72449  -46.72436 -28.00461 1.000 52.76163  ? 96  GLN B O   1 
ATOM   3280 C  CB  . GLN B 1 96  ? 65.43317  -48.18339 -29.23792 1.000 54.10293  ? 96  GLN B CB  1 
ATOM   3281 C  CG  . GLN B 1 96  ? 64.36501  -48.92218 -30.02899 1.000 63.80172  ? 96  GLN B CG  1 
ATOM   3282 C  CD  . GLN B 1 96  ? 63.54538  -49.88810 -29.18541 1.000 69.35228  ? 96  GLN B CD  1 
ATOM   3283 O  OE1 . GLN B 1 96  ? 63.74066  -50.00959 -27.97304 1.000 62.90099  ? 96  GLN B OE1 1 
ATOM   3284 N  NE2 . GLN B 1 96  ? 62.62050  -50.58658 -29.83350 1.000 70.80241  ? 96  GLN B NE2 1 
ATOM   3285 N  N   . LEU B 1 97  ? 64.26497  -47.19966 -26.43843 1.000 49.10079  ? 97  LEU B N   1 
ATOM   3286 C  CA  . LEU B 1 97  ? 63.25958  -47.29395 -25.38574 1.000 50.64569  ? 97  LEU B CA  1 
ATOM   3287 C  C   . LEU B 1 97  ? 62.82117  -45.91678 -24.89719 1.000 51.31413  ? 97  LEU B C   1 
ATOM   3288 O  O   . LEU B 1 97  ? 61.62221  -45.67833 -24.71294 1.000 54.50264  ? 97  LEU B O   1 
ATOM   3289 C  CB  . LEU B 1 97  ? 63.79725  -48.13213 -24.22395 1.000 47.02409  ? 97  LEU B CB  1 
ATOM   3290 C  CG  . LEU B 1 97  ? 62.90019  -48.28630 -22.99494 1.000 51.36772  ? 97  LEU B CG  1 
ATOM   3291 C  CD1 . LEU B 1 97  ? 61.53615  -48.81944 -23.39626 1.000 47.16949  ? 97  LEU B CD1 1 
ATOM   3292 C  CD2 . LEU B 1 97  ? 63.55391  -49.19775 -21.96303 1.000 50.41484  ? 97  LEU B CD2 1 
ATOM   3293 N  N   . THR B 1 98  ? 63.77087  -44.99814 -24.68782 1.000 47.65013  ? 98  THR B N   1 
ATOM   3294 C  CA  . THR B 1 98  ? 63.42316  -43.69497 -24.12567 1.000 52.87317  ? 98  THR B CA  1 
ATOM   3295 C  C   . THR B 1 98  ? 62.51663  -42.90806 -25.06365 1.000 53.11179  ? 98  THR B C   1 
ATOM   3296 O  O   . THR B 1 98  ? 61.63175  -42.17304 -24.60823 1.000 50.22075  ? 98  THR B O   1 
ATOM   3297 C  CB  . THR B 1 98  ? 64.68629  -42.88942 -23.81095 1.000 50.64488  ? 98  THR B CB  1 
ATOM   3298 O  OG1 . THR B 1 98  ? 65.42922  -42.65817 -25.01570 1.000 50.51159  ? 98  THR B OG1 1 
ATOM   3299 C  CG2 . THR B 1 98  ? 65.55843  -43.62548 -22.80150 1.000 47.44029  ? 98  THR B CG2 1 
ATOM   3300 N  N   . ASP B 1 99  ? 62.72129  -43.04637 -26.37758 1.000 51.00324  ? 99  ASP B N   1 
ATOM   3301 C  CA  . ASP B 1 99  ? 61.85986  -42.35448 -27.33158 1.000 50.37333  ? 99  ASP B CA  1 
ATOM   3302 C  C   . ASP B 1 99  ? 60.42030  -42.84385 -27.23028 1.000 47.72509  ? 99  ASP B C   1 
ATOM   3303 O  O   . ASP B 1 99  ? 59.47721  -42.05619 -27.36807 1.000 53.50605  ? 99  ASP B O   1 
ATOM   3304 C  CB  . ASP B 1 99  ? 62.39105  -42.53736 -28.75409 1.000 55.60440  ? 99  ASP B CB  1 
ATOM   3305 C  CG  . ASP B 1 99  ? 63.41798  -41.48678 -29.13523 1.000 56.34235  ? 99  ASP B CG  1 
ATOM   3306 O  OD1 . ASP B 1 99  ? 63.74080  -40.63308 -28.28617 1.000 59.43178  ? 99  ASP B OD1 1 
ATOM   3307 O  OD2 . ASP B 1 99  ? 63.89670  -41.51058 -30.28836 1.000 67.38924  ? 99  ASP B OD2 1 
ATOM   3308 N  N   . GLN B 1 100 ? 60.22963  -44.14179 -26.98620 1.000 48.05278  ? 100 GLN B N   1 
ATOM   3309 C  CA  . GLN B 1 100 ? 58.87662  -44.66699 -26.84118 1.000 52.78030  ? 100 GLN B CA  1 
ATOM   3310 C  C   . GLN B 1 100 ? 58.20170  -44.13767 -25.58325 1.000 51.51703  ? 100 GLN B C   1 
ATOM   3311 O  O   . GLN B 1 100 ? 56.98463  -43.92381 -25.57900 1.000 53.56282  ? 100 GLN B O   1 
ATOM   3312 C  CB  . GLN B 1 100 ? 58.90237  -46.19510 -26.82841 1.000 51.92773  ? 100 GLN B CB  1 
ATOM   3313 C  CG  . GLN B 1 100 ? 59.44194  -46.81628 -28.10862 1.000 58.82872  ? 100 GLN B CG  1 
ATOM   3314 C  CD  . GLN B 1 100 ? 59.35407  -48.32930 -28.10230 1.000 64.03775  ? 100 GLN B CD  1 
ATOM   3315 O  OE1 . GLN B 1 100 ? 58.26247  -48.89905 -28.09049 1.000 67.49416  ? 100 GLN B OE1 1 
ATOM   3316 N  NE2 . GLN B 1 100 ? 60.50663  -48.98925 -28.10536 1.000 60.94233  ? 100 GLN B NE2 1 
ATOM   3317 N  N   . VAL B 1 101 ? 58.96756  -43.91824 -24.51325 1.000 50.58011  ? 101 VAL B N   1 
ATOM   3318 C  CA  . VAL B 1 101 ? 58.39075  -43.37451 -23.28772 1.000 45.46506  ? 101 VAL B CA  1 
ATOM   3319 C  C   . VAL B 1 101 ? 58.11466  -41.88546 -23.44792 1.000 48.22307  ? 101 VAL B C   1 
ATOM   3320 O  O   . VAL B 1 101 ? 57.02228  -41.40216 -23.13004 1.000 47.18383  ? 101 VAL B O   1 
ATOM   3321 C  CB  . VAL B 1 101 ? 59.31612  -43.64870 -22.08844 1.000 50.60713  ? 101 VAL B CB  1 
ATOM   3322 C  CG1 . VAL B 1 101 ? 58.72182  -43.05858 -20.81376 1.000 46.13047  ? 101 VAL B CG1 1 
ATOM   3323 C  CG2 . VAL B 1 101 ? 59.56534  -45.14572 -21.93446 1.000 45.99371  ? 101 VAL B CG2 1 
ATOM   3324 N  N   . ALA B 1 102 ? 59.09861  -41.13744 -23.95366 1.000 45.69317  ? 102 ALA B N   1 
ATOM   3325 C  CA  . ALA B 1 102 ? 58.94700  -39.69315 -24.08793 1.000 49.83966  ? 102 ALA B CA  1 
ATOM   3326 C  C   . ALA B 1 102 ? 57.86659  -39.30793 -25.08957 1.000 56.37333  ? 102 ALA B C   1 
ATOM   3327 O  O   . ALA B 1 102 ? 57.41296  -38.15815 -25.07816 1.000 56.49479  ? 102 ALA B O   1 
ATOM   3328 C  CB  . ALA B 1 102 ? 60.27741  -39.05985 -24.49498 1.000 47.96051  ? 102 ALA B CB  1 
ATOM   3329 N  N   . ALA B 1 103 ? 57.44981  -40.23634 -25.95673 1.000 56.93091  ? 103 ALA B N   1 
ATOM   3330 C  CA  . ALA B 1 103 ? 56.37492  -39.94303 -26.89960 1.000 55.12851  ? 103 ALA B CA  1 
ATOM   3331 C  C   . ALA B 1 103 ? 55.08960  -39.56195 -26.17909 1.000 56.85837  ? 103 ALA B C   1 
ATOM   3332 O  O   . ALA B 1 103 ? 54.29604  -38.77086 -26.70233 1.000 57.04877  ? 103 ALA B O   1 
ATOM   3333 C  CB  . ALA B 1 103 ? 56.13396  -41.14447 -27.81447 1.000 44.47196  ? 103 ALA B CB  1 
ATOM   3334 N  N   . ALA B 1 104 ? 54.87642  -40.09972 -24.97386 1.000 56.27607  ? 104 ALA B N   1 
ATOM   3335 C  CA  . ALA B 1 104 ? 53.67669  -39.77376 -24.21060 1.000 53.48632  ? 104 ALA B CA  1 
ATOM   3336 C  C   . ALA B 1 104 ? 53.58246  -38.28287 -23.91432 1.000 55.96544  ? 104 ALA B C   1 
ATOM   3337 O  O   . ALA B 1 104 ? 52.48072  -37.76003 -23.71354 1.000 55.73733  ? 104 ALA B O   1 
ATOM   3338 C  CB  . ALA B 1 104 ? 53.65100  -40.57919 -22.91184 1.000 50.61368  ? 104 ALA B CB  1 
ATOM   3339 N  N   . LEU B 1 105 ? 54.71998  -37.58281 -23.88943 1.000 57.75203  ? 105 LEU B N   1 
ATOM   3340 C  CA  . LEU B 1 105 ? 54.70424  -36.14401 -23.64457 1.000 60.40178  ? 105 LEU B CA  1 
ATOM   3341 C  C   . LEU B 1 105 ? 54.02353  -35.38157 -24.77433 1.000 62.22264  ? 105 LEU B C   1 
ATOM   3342 O  O   . LEU B 1 105 ? 53.49467  -34.28678 -24.54988 1.000 66.19145  ? 105 LEU B O   1 
ATOM   3343 C  CB  . LEU B 1 105 ? 56.13061  -35.62603 -23.45584 1.000 55.21397  ? 105 LEU B CB  1 
ATOM   3344 C  CG  . LEU B 1 105 ? 56.91687  -36.14251 -22.25161 1.000 54.51455  ? 105 LEU B CG  1 
ATOM   3345 C  CD1 . LEU B 1 105 ? 58.35223  -35.66013 -22.32396 1.000 50.14361  ? 105 LEU B CD1 1 
ATOM   3346 C  CD2 . LEU B 1 105 ? 56.26421  -35.69452 -20.95493 1.000 48.14145  ? 105 LEU B CD2 1 
ATOM   3347 N  N   . ASP B 1 106 ? 54.02609  -35.93529 -25.98539 1.000 59.61564  ? 106 ASP B N   1 
ATOM   3348 C  CA  . ASP B 1 106 ? 53.51773  -35.23648 -27.15830 1.000 66.12586  ? 106 ASP B CA  1 
ATOM   3349 C  C   . ASP B 1 106 ? 52.09013  -35.61782 -27.52339 1.000 69.49261  ? 106 ASP B C   1 
ATOM   3350 O  O   . ASP B 1 106 ? 51.36929  -34.79277 -28.09400 1.000 74.43695  ? 106 ASP B O   1 
ATOM   3351 C  CB  . ASP B 1 106 ? 54.43340  -35.49947 -28.35883 1.000 64.25757  ? 106 ASP B CB  1 
ATOM   3352 C  CG  . ASP B 1 106 ? 55.89280  -35.22208 -28.04782 1.000 65.02758  ? 106 ASP B CG  1 
ATOM   3353 O  OD1 . ASP B 1 106 ? 56.17680  -34.21975 -27.35744 1.000 69.10588  ? 106 ASP B OD1 1 
ATOM   3354 O  OD2 . ASP B 1 106 ? 56.75584  -36.01184 -28.48421 1.000 67.36341  ? 106 ASP B OD2 1 
ATOM   3355 N  N   . GLY B 1 107 ? 51.66182  -36.83768 -27.21239 1.000 65.85051  ? 107 GLY B N   1 
ATOM   3356 C  CA  . GLY B 1 107 ? 50.32441  -37.27232 -27.53307 1.000 66.11211  ? 107 GLY B CA  1 
ATOM   3357 C  C   . GLY B 1 107 ? 50.02032  -38.65473 -26.99641 1.000 64.85868  ? 107 GLY B C   1 
ATOM   3358 O  O   . GLY B 1 107 ? 50.76403  -39.20858 -26.18077 1.000 67.40542  ? 107 GLY B O   1 
ATOM   3359 N  N   . PRO B 1 108 ? 48.91039  -39.23713 -27.44396 1.000 68.52552  ? 108 PRO B N   1 
ATOM   3360 C  CA  . PRO B 1 108 ? 48.54431  -40.57910 -26.98075 1.000 66.18585  ? 108 PRO B CA  1 
ATOM   3361 C  C   . PRO B 1 108 ? 49.54411  -41.62537 -27.44429 1.000 65.14685  ? 108 PRO B C   1 
ATOM   3362 O  O   . PRO B 1 108 ? 50.20066  -41.48136 -28.47843 1.000 67.11483  ? 108 PRO B O   1 
ATOM   3363 C  CB  . PRO B 1 108 ? 47.16682  -40.81172 -27.61486 1.000 61.84123  ? 108 PRO B CB  1 
ATOM   3364 C  CG  . PRO B 1 108 ? 46.65856  -39.44584 -27.94575 1.000 63.35339  ? 108 PRO B CG  1 
ATOM   3365 C  CD  . PRO B 1 108 ? 47.87138  -38.64740 -28.30292 1.000 68.12166  ? 108 PRO B CD  1 
ATOM   3366 N  N   . LEU B 1 109 ? 49.65302  -42.69395 -26.65756 1.000 65.22680  ? 109 LEU B N   1 
ATOM   3367 C  CA  . LEU B 1 109 ? 50.58112  -43.74204 -27.04876 1.000 66.85519  ? 109 LEU B CA  1 
ATOM   3368 C  C   . LEU B 1 109 ? 49.87914  -44.80539 -27.88603 1.000 71.81161  ? 109 LEU B C   1 
ATOM   3369 O  O   . LEU B 1 109 ? 48.70476  -45.11387 -27.65435 1.000 67.72987  ? 109 LEU B O   1 
ATOM   3370 C  CB  . LEU B 1 109 ? 51.19461  -44.40326 -25.81824 1.000 58.58645  ? 109 LEU B CB  1 
ATOM   3371 C  CG  . LEU B 1 109 ? 52.24258  -43.63196 -25.01821 1.000 61.15834  ? 109 LEU B CG  1 
ATOM   3372 C  CD1 . LEU B 1 109 ? 52.78663  -44.51915 -23.91203 1.000 54.49610  ? 109 LEU B CD1 1 
ATOM   3373 C  CD2 . LEU B 1 109 ? 53.36321  -43.13792 -25.92046 1.000 55.13653  ? 109 LEU B CD2 1 
ATOM   3374 N  N   . PRO B 1 110 ? 50.58370  -45.38211 -28.85949 1.000 69.31401  ? 110 PRO B N   1 
ATOM   3375 C  CA  . PRO B 1 110 ? 50.04017  -46.54837 -29.56176 1.000 70.57324  ? 110 PRO B CA  1 
ATOM   3376 C  C   . PRO B 1 110 ? 49.82811  -47.70107 -28.59353 1.000 71.12281  ? 110 PRO B C   1 
ATOM   3377 O  O   . PRO B 1 110 ? 50.48681  -47.79798 -27.55605 1.000 69.21781  ? 110 PRO B O   1 
ATOM   3378 C  CB  . PRO B 1 110 ? 51.12118  -46.87683 -30.59863 1.000 71.64920  ? 110 PRO B CB  1 
ATOM   3379 C  CG  . PRO B 1 110 ? 52.37579  -46.28489 -30.03573 1.000 67.25956  ? 110 PRO B CG  1 
ATOM   3380 C  CD  . PRO B 1 110 ? 51.93964  -45.03826 -29.32150 1.000 64.23934  ? 110 PRO B CD  1 
ATOM   3381 N  N   . ASP B 1 111 ? 48.88785  -48.58158 -28.94066 1.000 69.37400  ? 111 ASP B N   1 
ATOM   3382 C  CA  . ASP B 1 111 ? 48.60414  -49.72888 -28.08710 1.000 71.17568  ? 111 ASP B CA  1 
ATOM   3383 C  C   . ASP B 1 111 ? 49.78511  -50.68629 -27.99812 1.000 70.62083  ? 111 ASP B C   1 
ATOM   3384 O  O   . ASP B 1 111 ? 49.87248  -51.45761 -27.03681 1.000 69.09941  ? 111 ASP B O   1 
ATOM   3385 C  CB  . ASP B 1 111 ? 47.36652  -50.46731 -28.59741 1.000 75.48379  ? 111 ASP B CB  1 
ATOM   3386 C  CG  . ASP B 1 111 ? 46.19812  -49.53514 -28.85275 1.000 84.00040  ? 111 ASP B CG  1 
ATOM   3387 O  OD1 . ASP B 1 111 ? 46.18021  -48.88081 -29.91781 1.000 89.43149  ? 111 ASP B OD1 1 
ATOM   3388 O  OD2 . ASP B 1 111 ? 45.30220  -49.45013 -27.98689 1.000 85.63878  ? 111 ASP B OD2 1 
ATOM   3389 N  N   . THR B 1 112 ? 50.69692  -50.64392 -28.96907 1.000 68.00590  ? 112 THR B N   1 
ATOM   3390 C  CA  . THR B 1 112 ? 51.86064  -51.51922 -28.98629 1.000 69.83104  ? 112 THR B CA  1 
ATOM   3391 C  C   . THR B 1 112 ? 52.99292  -51.03033 -28.08982 1.000 73.95982  ? 112 THR B C   1 
ATOM   3392 O  O   . THR B 1 112 ? 53.98972  -51.74637 -27.93695 1.000 66.64571  ? 112 THR B O   1 
ATOM   3393 C  CB  . THR B 1 112 ? 52.37504  -51.66536 -30.42011 1.000 71.75093  ? 112 THR B CB  1 
ATOM   3394 O  OG1 . THR B 1 112 ? 52.73372  -50.37489 -30.93071 1.000 72.01917  ? 112 THR B OG1 1 
ATOM   3395 C  CG2 . THR B 1 112 ? 51.30109  -52.27413 -31.31290 1.000 69.52617  ? 112 THR B CG2 1 
ATOM   3396 N  N   . ALA B 1 113 ? 52.86537  -49.84218 -27.50014 1.000 70.73287  ? 113 ALA B N   1 
ATOM   3397 C  CA  . ALA B 1 113 ? 53.92385  -49.29703 -26.66482 1.000 64.81125  ? 113 ALA B CA  1 
ATOM   3398 C  C   . ALA B 1 113 ? 54.15648  -50.19340 -25.44820 1.000 62.22464  ? 113 ALA B C   1 
ATOM   3399 O  O   . ALA B 1 113 ? 53.22911  -50.85001 -24.96507 1.000 68.29817  ? 113 ALA B O   1 
ATOM   3400 C  CB  . ALA B 1 113 ? 53.57040  -47.87962 -26.21684 1.000 60.39766  ? 113 ALA B CB  1 
ATOM   3401 N  N   . PRO B 1 114 ? 55.38440  -50.24221 -24.93658 1.000 57.70186  ? 114 PRO B N   1 
ATOM   3402 C  CA  . PRO B 1 114 ? 55.69125  -51.13063 -23.80814 1.000 54.76567  ? 114 PRO B CA  1 
ATOM   3403 C  C   . PRO B 1 114 ? 54.91766  -50.72707 -22.56710 1.000 54.67873  ? 114 PRO B C   1 
ATOM   3404 O  O   . PRO B 1 114 ? 54.43599  -49.58836 -22.46798 1.000 56.52931  ? 114 PRO B O   1 
ATOM   3405 C  CB  . PRO B 1 114 ? 57.20317  -50.93843 -23.60643 1.000 54.40935  ? 114 PRO B CB  1 
ATOM   3406 C  CG  . PRO B 1 114 ? 57.69615  -50.35327 -24.88572 1.000 59.66891  ? 114 PRO B CG  1 
ATOM   3407 C  CD  . PRO B 1 114 ? 56.57547  -49.51286 -25.40051 1.000 59.24772  ? 114 PRO B CD  1 
ATOM   3408 N  N   . PRO B 1 115 ? 54.76809  -51.63639 -21.59949 1.000 53.61721  ? 115 PRO B N   1 
ATOM   3409 C  CA  . PRO B 1 115 ? 54.06000  -51.26828 -20.36183 1.000 55.36389  ? 115 PRO B CA  1 
ATOM   3410 C  C   . PRO B 1 115 ? 54.70591  -50.11329 -19.61821 1.000 56.93586  ? 115 PRO B C   1 
ATOM   3411 O  O   . PRO B 1 115 ? 53.99331  -49.26209 -19.06930 1.000 51.73353  ? 115 PRO B O   1 
ATOM   3412 C  CB  . PRO B 1 115 ? 54.10141  -52.56491 -19.54228 1.000 54.12573  ? 115 PRO B CB  1 
ATOM   3413 C  CG  . PRO B 1 115 ? 54.24089  -53.64470 -20.55533 1.000 56.53905  ? 115 PRO B CG  1 
ATOM   3414 C  CD  . PRO B 1 115 ? 55.09471  -53.07074 -21.64455 1.000 58.20999  ? 115 PRO B CD  1 
ATOM   3415 N  N   . ILE B 1 116 ? 56.04142  -50.05727 -19.58673 1.000 51.73353  ? 116 ILE B N   1 
ATOM   3416 C  CA  . ILE B 1 116 ? 56.72182  -48.95639 -18.90977 1.000 52.05625  ? 116 ILE B CA  1 
ATOM   3417 C  C   . ILE B 1 116 ? 56.37059  -47.62738 -19.56504 1.000 52.94090  ? 116 ILE B C   1 
ATOM   3418 O  O   . ILE B 1 116 ? 56.35713  -46.58200 -18.90164 1.000 50.40152  ? 116 ILE B O   1 
ATOM   3419 C  CB  . ILE B 1 116 ? 58.24606  -49.19969 -18.88668 1.000 46.51662  ? 116 ILE B CB  1 
ATOM   3420 C  CG1 . ILE B 1 116 ? 58.92408  -48.27614 -17.87110 1.000 49.98683  ? 116 ILE B CG1 1 
ATOM   3421 C  CG2 . ILE B 1 116 ? 58.85133  -49.01187 -20.27106 1.000 50.42142  ? 116 ILE B CG2 1 
ATOM   3422 C  CD1 . ILE B 1 116 ? 58.65167  -48.64873 -16.42357 1.000 41.46103  ? 116 ILE B CD1 1 
ATOM   3423 N  N   . ALA B 1 117 ? 56.06214  -47.64410 -20.86520 1.000 44.90848  ? 117 ALA B N   1 
ATOM   3424 C  CA  . ALA B 1 117 ? 55.64005  -46.42593 -21.54681 1.000 46.11849  ? 117 ALA B CA  1 
ATOM   3425 C  C   . ALA B 1 117 ? 54.21223  -46.05330 -21.16635 1.000 51.44918  ? 117 ALA B C   1 
ATOM   3426 O  O   . ALA B 1 117 ? 53.91793  -44.88423 -20.88636 1.000 54.24999  ? 117 ALA B O   1 
ATOM   3427 C  CB  . ALA B 1 117 ? 55.77326  -46.60006 -23.06011 1.000 51.59619  ? 117 ALA B CB  1 
ATOM   3428 N  N   . HIS B 1 118 ? 53.30755  -47.03671 -21.15524 1.000 52.49938  ? 118 HIS B N   1 
ATOM   3429 C  CA  . HIS B 1 118 ? 51.93676  -46.77171 -20.72765 1.000 55.45225  ? 118 HIS B CA  1 
ATOM   3430 C  C   . HIS B 1 118 ? 51.88736  -46.35273 -19.26439 1.000 54.06786  ? 118 HIS B C   1 
ATOM   3431 O  O   . HIS B 1 118 ? 51.05711  -45.52131 -18.87604 1.000 55.65688  ? 118 HIS B O   1 
ATOM   3432 C  CB  . HIS B 1 118 ? 51.05962  -48.00109 -20.96370 1.000 57.04446  ? 118 HIS B CB  1 
ATOM   3433 C  CG  . HIS B 1 118 ? 50.82481  -48.30317 -22.40961 1.000 56.89851  ? 118 HIS B CG  1 
ATOM   3434 N  ND1 . HIS B 1 118 ? 50.18468  -47.42511 -23.25709 1.000 59.34517  ? 118 HIS B ND1 1 
ATOM   3435 C  CD2 . HIS B 1 118 ? 51.14043  -49.38667 -23.15770 1.000 53.13652  ? 118 HIS B CD2 1 
ATOM   3436 C  CE1 . HIS B 1 118 ? 50.12003  -47.95317 -24.46634 1.000 63.51027  ? 118 HIS B CE1 1 
ATOM   3437 N  NE2 . HIS B 1 118 ? 50.69180  -49.14357 -24.43277 1.000 64.74790  ? 118 HIS B NE2 1 
ATOM   3438 N  N   . GLY B 1 119 ? 52.76226  -46.92367 -18.43487 1.000 51.41034  ? 119 GLY B N   1 
ATOM   3439 C  CA  . GLY B 1 119 ? 52.84900  -46.47415 -17.05481 1.000 50.84047  ? 119 GLY B CA  1 
ATOM   3440 C  C   . GLY B 1 119 ? 53.20626  -45.00427 -16.95192 1.000 48.88079  ? 119 GLY B C   1 
ATOM   3441 O  O   . GLY B 1 119 ? 52.58890  -44.25143 -16.19589 1.000 51.09617  ? 119 GLY B O   1 
ATOM   3442 N  N   . PHE B 1 120 ? 54.20418  -44.57326 -17.72563 1.000 49.25802  ? 120 PHE B N   1 
ATOM   3443 C  CA  . PHE B 1 120 ? 54.59442  -43.16803 -17.70879 1.000 49.93607  ? 120 PHE B CA  1 
ATOM   3444 C  C   . PHE B 1 120 ? 53.47425  -42.27430 -18.22708 1.000 52.87125  ? 120 PHE B C   1 
ATOM   3445 O  O   . PHE B 1 120 ? 53.23758  -41.18745 -17.68532 1.000 51.56108  ? 120 PHE B O   1 
ATOM   3446 C  CB  . PHE B 1 120 ? 55.86396  -42.96601 -18.53431 1.000 41.49790  ? 120 PHE B CB  1 
ATOM   3447 C  CG  . PHE B 1 120 ? 56.35140  -41.54637 -18.55435 1.000 46.30703  ? 120 PHE B CG  1 
ATOM   3448 C  CD1 . PHE B 1 120 ? 57.05771  -41.02959 -17.48102 1.000 45.77240  ? 120 PHE B CD1 1 
ATOM   3449 C  CD2 . PHE B 1 120 ? 56.11016  -40.72962 -19.64682 1.000 46.41513  ? 120 PHE B CD2 1 
ATOM   3450 C  CE1 . PHE B 1 120 ? 57.51226  -39.72327 -17.49405 1.000 47.23735  ? 120 PHE B CE1 1 
ATOM   3451 C  CE2 . PHE B 1 120 ? 56.56125  -39.42151 -19.66548 1.000 48.65350  ? 120 PHE B CE2 1 
ATOM   3452 C  CZ  . PHE B 1 120 ? 57.26363  -38.91845 -18.58664 1.000 45.50139  ? 120 PHE B CZ  1 
ATOM   3453 N  N   . ALA B 1 121 ? 52.77767  -42.71351 -19.28032 1.000 54.85547  ? 121 ALA B N   1 
ATOM   3454 C  CA  . ALA B 1 121 ? 51.70128  -41.90779 -19.84996 1.000 51.96453  ? 121 ALA B CA  1 
ATOM   3455 C  C   . ALA B 1 121 ? 50.58548  -41.67790 -18.83806 1.000 50.53001  ? 121 ALA B C   1 
ATOM   3456 O  O   . ALA B 1 121 ? 49.97620  -40.60182 -18.80612 1.000 54.53433  ? 121 ALA B O   1 
ATOM   3457 C  CB  . ALA B 1 121 ? 51.15550  -42.57964 -21.10980 1.000 49.63365  ? 121 ALA B CB  1 
ATOM   3458 N  N   . ASP B 1 122 ? 50.30563  -42.67680 -17.99949 1.000 49.34403  ? 122 ASP B N   1 
ATOM   3459 C  CA  . ASP B 1 122 ? 49.27814  -42.51394 -16.97661 1.000 53.56161  ? 122 ASP B CA  1 
ATOM   3460 C  C   . ASP B 1 122 ? 49.73579  -41.55650 -15.88184 1.000 60.69102  ? 122 ASP B C   1 
ATOM   3461 O  O   . ASP B 1 122 ? 48.93740  -40.76333 -15.36862 1.000 56.66839  ? 122 ASP B O   1 
ATOM   3462 C  CB  . ASP B 1 122 ? 48.90919  -43.87421 -16.38729 1.000 45.98998  ? 122 ASP B CB  1 
ATOM   3463 C  CG  . ASP B 1 122 ? 47.79574  -43.78310 -15.36386 1.000 59.15897  ? 122 ASP B CG  1 
ATOM   3464 O  OD1 . ASP B 1 122 ? 46.73709  -43.20403 -15.68710 1.000 69.04854  ? 122 ASP B OD1 1 
ATOM   3465 O  OD2 . ASP B 1 122 ? 47.97555  -44.29741 -14.24006 1.000 58.25967  ? 122 ASP B OD2 1 
ATOM   3466 N  N   . ILE B 1 123 ? 51.01690  -41.61611 -15.51181 1.000 54.58105  ? 123 ILE B N   1 
ATOM   3467 C  CA  . ILE B 1 123 ? 51.55952  -40.66423 -14.54743 1.000 50.35540  ? 123 ILE B CA  1 
ATOM   3468 C  C   . ILE B 1 123 ? 51.49786  -39.25003 -15.10638 1.000 50.96939  ? 123 ILE B C   1 
ATOM   3469 O  O   . ILE B 1 123 ? 51.11915  -38.30293 -14.40628 1.000 48.19423  ? 123 ILE B O   1 
ATOM   3470 C  CB  . ILE B 1 123 ? 52.99941  -41.05560 -14.16953 1.000 52.45061  ? 123 ILE B CB  1 
ATOM   3471 C  CG1 . ILE B 1 123 ? 53.01525  -42.40681 -13.46052 1.000 49.61535  ? 123 ILE B CG1 1 
ATOM   3472 C  CG2 . ILE B 1 123 ? 53.64694  -39.97628 -13.30891 1.000 51.96985  ? 123 ILE B CG2 1 
ATOM   3473 C  CD1 . ILE B 1 123 ? 54.37817  -42.80626 -12.98624 1.000 49.51328  ? 123 ILE B CD1 1 
ATOM   3474 N  N   . TRP B 1 124 ? 51.86678  -39.08637 -16.37845 1.000 47.36639  ? 124 TRP B N   1 
ATOM   3475 C  CA  . TRP B 1 124 ? 51.90603  -37.75699 -16.97698 1.000 52.00249  ? 124 TRP B CA  1 
ATOM   3476 C  C   . TRP B 1 124 ? 50.50625  -37.18091 -17.13739 1.000 55.37370  ? 124 TRP B C   1 
ATOM   3477 O  O   . TRP B 1 124 ? 50.29614  -35.98139 -16.92267 1.000 53.41449  ? 124 TRP B O   1 
ATOM   3478 C  CB  . TRP B 1 124 ? 52.62730  -37.81512 -18.32318 1.000 46.99945  ? 124 TRP B CB  1 
ATOM   3479 C  CG  . TRP B 1 124 ? 52.75424  -36.48856 -19.00204 1.000 51.60790  ? 124 TRP B CG  1 
ATOM   3480 C  CD1 . TRP B 1 124 ? 52.27019  -36.14996 -20.23155 1.000 53.33955  ? 124 TRP B CD1 1 
ATOM   3481 C  CD2 . TRP B 1 124 ? 53.40592  -35.31587 -18.49031 1.000 52.59536  ? 124 TRP B CD2 1 
ATOM   3482 N  NE1 . TRP B 1 124 ? 52.58294  -34.84338 -20.51986 1.000 52.50899  ? 124 TRP B NE1 1 
ATOM   3483 C  CE2 . TRP B 1 124 ? 53.27871  -34.30909 -19.46698 1.000 52.14976  ? 124 TRP B CE2 1 
ATOM   3484 C  CE3 . TRP B 1 124 ? 54.08571  -35.02126 -17.30280 1.000 51.27019  ? 124 TRP B CE3 1 
ATOM   3485 C  CZ2 . TRP B 1 124 ? 53.80536  -33.02961 -19.29364 1.000 56.14331  ? 124 TRP B CZ2 1 
ATOM   3486 C  CZ3 . TRP B 1 124 ? 54.60645  -33.74971 -17.13273 1.000 49.58888  ? 124 TRP B CZ3 1 
ATOM   3487 C  CH2 . TRP B 1 124 ? 54.46249  -32.77061 -18.12176 1.000 54.06919  ? 124 TRP B CH2 1 
ATOM   3488 N  N   . ARG B 1 125 ? 49.53876  -38.01982 -17.51619 1.000 57.68016  ? 125 ARG B N   1 
ATOM   3489 C  CA  . ARG B 1 125 ? 48.15570  -37.56734 -17.62035 1.000 55.94237  ? 125 ARG B CA  1 
ATOM   3490 C  C   . ARG B 1 125 ? 47.67240  -36.98482 -16.29898 1.000 56.91503  ? 125 ARG B C   1 
ATOM   3491 O  O   . ARG B 1 125 ? 47.05140  -35.91648 -16.26404 1.000 61.84008  ? 125 ARG B O   1 
ATOM   3492 C  CB  . ARG B 1 125 ? 47.25907  -38.72753 -18.05792 1.000 62.85815  ? 125 ARG B CB  1 
ATOM   3493 C  CG  . ARG B 1 125 ? 45.77918  -38.38290 -18.10415 1.000 64.61467  ? 125 ARG B CG  1 
ATOM   3494 C  CD  . ARG B 1 125 ? 44.92040  -39.61919 -18.32511 1.000 59.09148  ? 125 ARG B CD  1 
ATOM   3495 N  NE  . ARG B 1 125 ? 45.13219  -40.63011 -17.29478 1.000 65.43548  ? 125 ARG B NE  1 
ATOM   3496 C  CZ  . ARG B 1 125 ? 44.61538  -40.57888 -16.07369 1.000 67.55175  ? 125 ARG B CZ  1 
ATOM   3497 N  NH1 . ARG B 1 125 ? 43.86254  -39.56342 -15.68204 1.000 66.06528  ? 125 ARG B NH1 1 
ATOM   3498 N  NH2 . ARG B 1 125 ? 44.86227  -41.57034 -15.22214 1.000 61.39051  ? 125 ARG B NH2 1 
ATOM   3499 N  N   . ARG B 1 126 ? 47.96592  -37.67465 -15.19453 1.000 55.25495  ? 126 ARG B N   1 
ATOM   3500 C  CA  . ARG B 1 126 ? 47.54468  -37.19696 -13.88274 1.000 55.95918  ? 126 ARG B CA  1 
ATOM   3501 C  C   . ARG B 1 126 ? 48.34409  -35.97858 -13.43973 1.000 57.68945  ? 126 ARG B C   1 
ATOM   3502 O  O   . ARG B 1 126 ? 47.81472  -35.11792 -12.72678 1.000 57.55459  ? 126 ARG B O   1 
ATOM   3503 C  CB  . ARG B 1 126 ? 47.68043  -38.31503 -12.84838 1.000 58.85654  ? 126 ARG B CB  1 
ATOM   3504 C  CG  . ARG B 1 126 ? 46.76227  -39.50494 -13.07533 1.000 56.00899  ? 126 ARG B CG  1 
ATOM   3505 C  CD  . ARG B 1 126 ? 46.92351  -40.52508 -11.95964 1.000 56.06582  ? 126 ARG B CD  1 
ATOM   3506 N  NE  . ARG B 1 126 ? 47.95452  -41.51178 -12.25641 1.000 57.04134  ? 126 ARG B NE  1 
ATOM   3507 C  CZ  . ARG B 1 126 ? 48.50618  -42.31334 -11.35474 1.000 57.04855  ? 126 ARG B CZ  1 
ATOM   3508 N  NH1 . ARG B 1 126 ? 48.18578  -42.23863 -10.07220 1.000 51.66885  ? 126 ARG B NH1 1 
ATOM   3509 N  NH2 . ARG B 1 126 ? 49.40528  -43.21009 -11.74825 1.000 55.40569  ? 126 ARG B NH2 1 
ATOM   3510 N  N   . THR B 1 127 ? 49.61360  -35.89095 -13.84478 1.000 52.39645  ? 127 THR B N   1 
ATOM   3511 C  CA  . THR B 1 127 ? 50.46501  -34.78878 -13.40738 1.000 56.51156  ? 127 THR B CA  1 
ATOM   3512 C  C   . THR B 1 127 ? 49.96930  -33.44624 -13.92979 1.000 57.21843  ? 127 THR B C   1 
ATOM   3513 O  O   . THR B 1 127 ? 50.09390  -32.42911 -13.23775 1.000 59.74813  ? 127 THR B O   1 
ATOM   3514 C  CB  . THR B 1 127 ? 51.90794  -35.03595 -13.85650 1.000 55.51700  ? 127 THR B CB  1 
ATOM   3515 O  OG1 . THR B 1 127 ? 52.39894  -36.23607 -13.24624 1.000 53.02807  ? 127 THR B OG1 1 
ATOM   3516 C  CG2 . THR B 1 127 ? 52.81151  -33.87006 -13.46905 1.000 55.88915  ? 127 THR B CG2 1 
ATOM   3517 N  N   . CYS B 1 128 ? 49.38798  -33.42455 -15.12809 1.000 57.59304  ? 128 CYS B N   1 
ATOM   3518 C  CA  . CYS B 1 128 ? 48.98359  -32.17818 -15.76391 1.000 62.30239  ? 128 CYS B CA  1 
ATOM   3519 C  C   . CYS B 1 128 ? 47.58602  -31.71699 -15.37738 1.000 62.47519  ? 128 CYS B C   1 
ATOM   3520 O  O   . CYS B 1 128 ? 47.23220  -30.56842 -15.66867 1.000 64.34272  ? 128 CYS B O   1 
ATOM   3521 C  CB  . CYS B 1 128 ? 49.06168  -32.32439 -17.28411 1.000 61.31154  ? 128 CYS B CB  1 
ATOM   3522 S  SG  . CYS B 1 128 ? 50.73370  -32.61741 -17.87785 1.000 72.18625  ? 128 CYS B SG  1 
ATOM   3523 N  N   . GLU B 1 129 ? 46.79051  -32.57512 -14.74009 1.000 60.12208  ? 129 GLU B N   1 
ATOM   3524 C  CA  . GLU B 1 129 ? 45.43229  -32.20583 -14.35888 1.000 64.61242  ? 129 GLU B CA  1 
ATOM   3525 C  C   . GLU B 1 129 ? 45.43767  -30.98050 -13.45409 1.000 65.33955  ? 129 GLU B C   1 
ATOM   3526 O  O   . GLU B 1 129 ? 46.12043  -30.95355 -12.42580 1.000 68.18553  ? 129 GLU B O   1 
ATOM   3527 C  CB  . GLU B 1 129 ? 44.74413  -33.37190 -13.64777 1.000 65.42980  ? 129 GLU B CB  1 
ATOM   3528 C  CG  . GLU B 1 129 ? 44.51559  -34.59834 -14.51551 1.000 71.61897  ? 129 GLU B CG  1 
ATOM   3529 C  CD  . GLU B 1 129 ? 44.04983  -35.79806 -13.70747 1.000 78.80965  ? 129 GLU B CD  1 
ATOM   3530 O  OE1 . GLU B 1 129 ? 44.27207  -35.81117 -12.47631 1.000 68.60924  ? 129 GLU B OE1 1 
ATOM   3531 O  OE2 . GLU B 1 129 ? 43.46131  -36.72738 -14.30116 1.000 80.72227  ? 129 GLU B OE2 1 
ATOM   3532 N  N   . GLY B 1 130 ? 44.67075  -29.96418 -13.84243 1.000 64.53446  ? 130 GLY B N   1 
ATOM   3533 C  CA  . GLY B 1 130 ? 44.51438  -28.77438 -13.03249 1.000 60.37045  ? 130 GLY B CA  1 
ATOM   3534 C  C   . GLY B 1 130 ? 45.71230  -27.85605 -12.98318 1.000 65.04163  ? 130 GLY B C   1 
ATOM   3535 O  O   . GLY B 1 130 ? 45.72605  -26.92971 -12.16464 1.000 67.55943  ? 130 GLY B O   1 
ATOM   3536 N  N   . MET B 1 131 ? 46.71646  -28.07700 -13.82518 1.000 64.43765  ? 131 MET B N   1 
ATOM   3537 C  CA  . MET B 1 131 ? 47.90227  -27.23677 -13.86977 1.000 63.85556  ? 131 MET B CA  1 
ATOM   3538 C  C   . MET B 1 131 ? 47.88002  -26.38106 -15.12981 1.000 60.86834  ? 131 MET B C   1 
ATOM   3539 O  O   . MET B 1 131 ? 47.28195  -26.75516 -16.14273 1.000 61.21629  ? 131 MET B O   1 
ATOM   3540 C  CB  . MET B 1 131 ? 49.17997  -28.08253 -13.82998 1.000 61.47061  ? 131 MET B CB  1 
ATOM   3541 C  CG  . MET B 1 131 ? 49.17573  -29.16136 -12.75761 1.000 56.88463  ? 131 MET B CG  1 
ATOM   3542 S  SD  . MET B 1 131 ? 49.19427  -28.51675 -11.07287 1.000 57.25232  ? 131 MET B SD  1 
ATOM   3543 C  CE  . MET B 1 131 ? 50.86798  -27.88383 -10.97521 1.000 59.02099  ? 131 MET B CE  1 
ATOM   3544 N  N   . THR B 1 132 ? 48.53864  -25.22638 -15.05770 1.000 60.00596  ? 132 THR B N   1 
ATOM   3545 C  CA  . THR B 1 132 ? 48.53959  -24.30187 -16.17917 1.000 57.02919  ? 132 THR B CA  1 
ATOM   3546 C  C   . THR B 1 132 ? 49.29208  -24.90366 -17.36608 1.000 64.24428  ? 132 THR B C   1 
ATOM   3547 O  O   . THR B 1 132 ? 50.21268  -25.70582 -17.18579 1.000 62.26465  ? 132 THR B O   1 
ATOM   3548 C  CB  . THR B 1 132 ? 49.17995  -22.97266 -15.78400 1.000 60.39805  ? 132 THR B CB  1 
ATOM   3549 O  OG1 . THR B 1 132 ? 50.57479  -23.16947 -15.51730 1.000 58.96016  ? 132 THR B OG1 1 
ATOM   3550 C  CG2 . THR B 1 132 ? 48.50384  -22.39925 -14.54308 1.000 55.82325  ? 132 THR B CG2 1 
ATOM   3551 N  N   . PRO B 1 133 ? 48.91061  -24.53893 -18.59399 1.000 63.98812  ? 133 PRO B N   1 
ATOM   3552 C  CA  . PRO B 1 133 ? 49.62388  -25.07381 -19.76596 1.000 61.14264  ? 133 PRO B CA  1 
ATOM   3553 C  C   . PRO B 1 133 ? 51.10267  -24.73239 -19.78035 1.000 59.30573  ? 133 PRO B C   1 
ATOM   3554 O  O   . PRO B 1 133 ? 51.90341  -25.50832 -20.31762 1.000 60.11937  ? 133 PRO B O   1 
ATOM   3555 C  CB  . PRO B 1 133 ? 48.88366  -24.43179 -20.94843 1.000 60.27746  ? 133 PRO B CB  1 
ATOM   3556 C  CG  . PRO B 1 133 ? 47.52909  -24.10649 -20.41496 1.000 60.64454  ? 133 PRO B CG  1 
ATOM   3557 C  CD  . PRO B 1 133 ? 47.74212  -23.72843 -18.97826 1.000 59.23987  ? 133 PRO B CD  1 
ATOM   3558 N  N   . ALA B 1 134 ? 51.49154  -23.58985 -19.20969 1.000 56.26301  ? 134 ALA B N   1 
ATOM   3559 C  CA  . ALA B 1 134 ? 52.90803  -23.25492 -19.12671 1.000 57.94963  ? 134 ALA B CA  1 
ATOM   3560 C  C   . ALA B 1 134 ? 53.63796  -24.16487 -18.14782 1.000 55.79428  ? 134 ALA B C   1 
ATOM   3561 O  O   . ALA B 1 134 ? 54.81451  -24.48088 -18.35541 1.000 60.08539  ? 134 ALA B O   1 
ATOM   3562 C  CB  . ALA B 1 134 ? 53.08105  -21.79030 -18.72540 1.000 55.09596  ? 134 ALA B CB  1 
ATOM   3563 N  N   . TRP B 1 135 ? 52.96090  -24.59666 -17.08206 1.000 58.18814  ? 135 TRP B N   1 
ATOM   3564 C  CA  . TRP B 1 135 ? 53.58090  -25.52431 -16.14338 1.000 56.10624  ? 135 TRP B CA  1 
ATOM   3565 C  C   . TRP B 1 135 ? 53.79543  -26.89106 -16.78059 1.000 56.07540  ? 135 TRP B C   1 
ATOM   3566 O  O   . TRP B 1 135 ? 54.85346  -27.50514 -16.60119 1.000 53.57691  ? 135 TRP B O   1 
ATOM   3567 C  CB  . TRP B 1 135 ? 52.72516  -25.65000 -14.88421 1.000 53.62818  ? 135 TRP B CB  1 
ATOM   3568 C  CG  . TRP B 1 135 ? 53.39784  -26.41299 -13.78574 1.000 50.63563  ? 135 TRP B CG  1 
ATOM   3569 C  CD1 . TRP B 1 135 ? 54.15782  -25.89501 -12.77832 1.000 54.44301  ? 135 TRP B CD1 1 
ATOM   3570 C  CD2 . TRP B 1 135 ? 53.37319  -27.83153 -13.58084 1.000 49.89929  ? 135 TRP B CD2 1 
ATOM   3571 N  NE1 . TRP B 1 135 ? 54.60680  -26.90098 -11.95820 1.000 54.81348  ? 135 TRP B NE1 1 
ATOM   3572 C  CE2 . TRP B 1 135 ? 54.13973  -28.09957 -12.42969 1.000 51.25566  ? 135 TRP B CE2 1 
ATOM   3573 C  CE3 . TRP B 1 135 ? 52.77793  -28.90036 -14.25820 1.000 53.67838  ? 135 TRP B CE3 1 
ATOM   3574 C  CZ2 . TRP B 1 135 ? 54.32651  -29.39031 -11.94127 1.000 49.53082  ? 135 TRP B CZ2 1 
ATOM   3575 C  CZ3 . TRP B 1 135 ? 52.96620  -30.18150 -13.77169 1.000 51.10678  ? 135 TRP B CZ3 1 
ATOM   3576 C  CH2 . TRP B 1 135 ? 53.73331  -30.41505 -12.62465 1.000 54.00647  ? 135 TRP B CH2 1 
ATOM   3577 N  N   . CYS B 1 136 ? 52.80159  -27.38268 -17.52530 1.000 56.46911  ? 136 CYS B N   1 
ATOM   3578 C  CA  . CYS B 1 136 ? 52.93722  -28.67161 -18.19740 1.000 60.21444  ? 136 CYS B CA  1 
ATOM   3579 C  C   . CYS B 1 136 ? 54.09133  -28.65372 -19.18992 1.000 54.25022  ? 136 CYS B C   1 
ATOM   3580 O  O   . CYS B 1 136 ? 54.88193  -29.60185 -19.25712 1.000 51.63247  ? 136 CYS B O   1 
ATOM   3581 C  CB  . CYS B 1 136 ? 51.63170  -29.03485 -18.90489 1.000 60.82243  ? 136 CYS B CB  1 
ATOM   3582 S  SG  . CYS B 1 136 ? 50.19491  -29.07492 -17.82140 1.000 79.91324  ? 136 CYS B SG  1 
ATOM   3583 N  N   . ALA B 1 137 ? 54.20287  -27.57612 -19.97146 1.000 54.80220  ? 137 ALA B N   1 
ATOM   3584 C  CA  . ALA B 1 137 ? 55.27457  -27.48458 -20.95799 1.000 56.93564  ? 137 ALA B CA  1 
ATOM   3585 C  C   . ALA B 1 137 ? 56.64447  -27.45511 -20.28961 1.000 53.17877  ? 137 ALA B C   1 
ATOM   3586 O  O   . ALA B 1 137 ? 57.58005  -28.12369 -20.74481 1.000 54.22439  ? 137 ALA B O   1 
ATOM   3587 C  CB  . ALA B 1 137 ? 55.07825  -26.24754 -21.83499 1.000 52.51834  ? 137 ALA B CB  1 
ATOM   3588 N  N   . ARG B 1 138 ? 56.78444  -26.68344 -19.20989 1.000 52.89647  ? 138 ARG B N   1 
ATOM   3589 C  CA  . ARG B 1 138 ? 58.06036  -26.62859 -18.50380 1.000 51.58616  ? 138 ARG B CA  1 
ATOM   3590 C  C   . ARG B 1 138 ? 58.40254  -27.98191 -17.89219 1.000 47.81579  ? 138 ARG B C   1 
ATOM   3591 O  O   . ARG B 1 138 ? 59.53881  -28.45618 -18.00115 1.000 52.27282  ? 138 ARG B O   1 
ATOM   3592 C  CB  . ARG B 1 138 ? 58.01933  -25.54129 -17.43042 1.000 48.69462  ? 138 ARG B CB  1 
ATOM   3593 C  CG  . ARG B 1 138 ? 59.37368  -25.23153 -16.81608 1.000 53.61801  ? 138 ARG B CG  1 
ATOM   3594 C  CD  . ARG B 1 138 ? 59.23301  -24.25694 -15.66209 1.000 53.41927  ? 138 ARG B CD  1 
ATOM   3595 N  NE  . ARG B 1 138 ? 58.51646  -24.85926 -14.54501 1.000 47.06557  ? 138 ARG B NE  1 
ATOM   3596 C  CZ  . ARG B 1 138 ? 57.81273  -24.17871 -13.65095 1.000 51.88215  ? 138 ARG B CZ  1 
ATOM   3597 N  NH1 . ARG B 1 138 ? 57.67830  -22.86491 -13.73116 1.000 50.84475  ? 138 ARG B NH1 1 
ATOM   3598 N  NH2 . ARG B 1 138 ? 57.22351  -24.83367 -12.65479 1.000 50.07723  ? 138 ARG B NH2 1 
ATOM   3599 N  N   . SER B 1 139 ? 57.42309  -28.62565 -17.25130 1.000 48.08905  ? 139 SER B N   1 
ATOM   3600 C  CA  . SER B 1 139 ? 57.65588  -29.95150 -16.68771 1.000 48.90863  ? 139 SER B CA  1 
ATOM   3601 C  C   . SER B 1 139 ? 57.91195  -30.98996 -17.77258 1.000 48.32274  ? 139 SER B C   1 
ATOM   3602 O  O   . SER B 1 139 ? 58.63422  -31.96517 -17.53613 1.000 47.13604  ? 139 SER B O   1 
ATOM   3603 C  CB  . SER B 1 139 ? 56.46914  -30.36905 -15.82186 1.000 47.15968  ? 139 SER B CB  1 
ATOM   3604 O  OG  . SER B 1 139 ? 56.30438  -29.47464 -14.73603 1.000 47.04099  ? 139 SER B OG  1 
ATOM   3605 N  N   . ALA B 1 140 ? 57.32951  -30.80411 -18.95953 1.000 50.26104  ? 140 ALA B N   1 
ATOM   3606 C  CA  . ALA B 1 140 ? 57.62501  -31.69901 -20.07320 1.000 51.22881  ? 140 ALA B CA  1 
ATOM   3607 C  C   . ALA B 1 140 ? 59.08587  -31.58992 -20.48798 1.000 46.68013  ? 140 ALA B C   1 
ATOM   3608 O  O   . ALA B 1 140 ? 59.74300  -32.60597 -20.74544 1.000 46.54546  ? 140 ALA B O   1 
ATOM   3609 C  CB  . ALA B 1 140 ? 56.70514  -31.39333 -21.25628 1.000 45.07208  ? 140 ALA B CB  1 
ATOM   3610 N  N   . ARG B 1 141 ? 59.61136  -30.36244 -20.55899 1.000 44.20031  ? 141 ARG B N   1 
ATOM   3611 C  CA  . ARG B 1 141 ? 61.02709  -30.18012 -20.86402 1.000 47.59655  ? 141 ARG B CA  1 
ATOM   3612 C  C   . ARG B 1 141 ? 61.90554  -30.86978 -19.82846 1.000 43.35416  ? 141 ARG B C   1 
ATOM   3613 O  O   . ARG B 1 141 ? 62.94618  -31.44370 -20.16879 1.000 46.55476  ? 141 ARG B O   1 
ATOM   3614 C  CB  . ARG B 1 141 ? 61.36701  -28.69153 -20.93784 1.000 49.89676  ? 141 ARG B CB  1 
ATOM   3615 C  CG  . ARG B 1 141 ? 60.68094  -27.94416 -22.06408 1.000 57.07195  ? 141 ARG B CG  1 
ATOM   3616 C  CD  . ARG B 1 141 ? 61.31151  -26.57205 -22.27619 1.000 66.15287  ? 141 ARG B CD  1 
ATOM   3617 N  NE  . ARG B 1 141 ? 61.15163  -25.69342 -21.12219 1.000 66.72322  ? 141 ARG B NE  1 
ATOM   3618 C  CZ  . ARG B 1 141 ? 60.15968  -24.82495 -20.97255 1.000 63.96602  ? 141 ARG B CZ  1 
ATOM   3619 N  NH1 . ARG B 1 141 ? 59.20818  -24.69755 -21.88319 1.000 62.22588  ? 141 ARG B NH1 1 
ATOM   3620 N  NH2 . ARG B 1 141 ? 60.12142  -24.06407 -19.88211 1.000 63.84547  ? 141 ARG B NH2 1 
ATOM   3621 N  N   . HIS B 1 142 ? 61.50150  -30.82269 -18.55698 1.000 42.41631  ? 142 HIS B N   1 
ATOM   3622 C  CA  . HIS B 1 142 ? 62.27353  -31.48272 -17.50932 1.000 48.43248  ? 142 HIS B CA  1 
ATOM   3623 C  C   . HIS B 1 142 ? 62.32984  -32.98755 -17.73320 1.000 44.22867  ? 142 HIS B C   1 
ATOM   3624 O  O   . HIS B 1 142 ? 63.37341  -33.61535 -17.51921 1.000 41.15876  ? 142 HIS B O   1 
ATOM   3625 C  CB  . HIS B 1 142 ? 61.67839  -31.16046 -16.13783 1.000 42.71552  ? 142 HIS B CB  1 
ATOM   3626 C  CG  . HIS B 1 142 ? 61.80305  -29.71967 -15.75106 1.000 44.81956  ? 142 HIS B CG  1 
ATOM   3627 N  ND1 . HIS B 1 142 ? 60.99028  -29.12838 -14.80834 1.000 43.53353  ? 142 HIS B ND1 1 
ATOM   3628 C  CD2 . HIS B 1 142 ? 62.64882  -28.75230 -16.17873 1.000 43.02527  ? 142 HIS B CD2 1 
ATOM   3629 C  CE1 . HIS B 1 142 ? 61.32946  -27.85864 -14.67246 1.000 49.81405  ? 142 HIS B CE1 1 
ATOM   3630 N  NE2 . HIS B 1 142 ? 62.33335  -27.60510 -15.49264 1.000 43.62174  ? 142 HIS B NE2 1 
ATOM   3631 N  N   . TRP B 1 143 ? 61.21876  -33.58344 -18.17235 1.000 41.91875  ? 143 TRP B N   1 
ATOM   3632 C  CA  . TRP B 1 143 ? 61.22791  -35.00812 -18.48313 1.000 39.64595  ? 143 TRP B CA  1 
ATOM   3633 C  C   . TRP B 1 143 ? 62.14757  -35.31360 -19.65924 1.000 43.50075  ? 143 TRP B C   1 
ATOM   3634 O  O   . TRP B 1 143 ? 62.86774  -36.31817 -19.64685 1.000 40.93457  ? 143 TRP B O   1 
ATOM   3635 C  CB  . TRP B 1 143 ? 59.80829  -35.49614 -18.76783 1.000 42.08234  ? 143 TRP B CB  1 
ATOM   3636 C  CG  . TRP B 1 143 ? 59.03661  -35.83529 -17.53137 1.000 45.09477  ? 143 TRP B CG  1 
ATOM   3637 C  CD1 . TRP B 1 143 ? 57.86272  -35.27915 -17.11937 1.000 43.06339  ? 143 TRP B CD1 1 
ATOM   3638 C  CD2 . TRP B 1 143 ? 59.39286  -36.80530 -16.53701 1.000 46.80592  ? 143 TRP B CD2 1 
ATOM   3639 N  NE1 . TRP B 1 143 ? 57.45970  -35.84749 -15.93590 1.000 44.76905  ? 143 TRP B NE1 1 
ATOM   3640 C  CE2 . TRP B 1 143 ? 58.38293  -36.78570 -15.55544 1.000 45.86623  ? 143 TRP B CE2 1 
ATOM   3641 C  CE3 . TRP B 1 143 ? 60.46572  -37.69085 -16.38426 1.000 45.60837  ? 143 TRP B CE3 1 
ATOM   3642 C  CZ2 . TRP B 1 143 ? 58.41239  -37.61676 -14.43670 1.000 44.71891  ? 143 TRP B CZ2 1 
ATOM   3643 C  CZ3 . TRP B 1 143 ? 60.49492  -38.51410 -15.26999 1.000 44.91589  ? 143 TRP B CZ3 1 
ATOM   3644 C  CH2 . TRP B 1 143 ? 59.47454  -38.47142 -14.31263 1.000 46.01516  ? 143 TRP B CH2 1 
ATOM   3645 N  N   . ARG B 1 144 ? 62.14565  -34.45584 -20.68284 1.000 44.14232  ? 144 ARG B N   1 
ATOM   3646 C  CA  . ARG B 1 144 ? 62.98863  -34.70969 -21.84719 1.000 50.29935  ? 144 ARG B CA  1 
ATOM   3647 C  C   . ARG B 1 144 ? 64.46738  -34.62184 -21.49270 1.000 45.28603  ? 144 ARG B C   1 
ATOM   3648 O  O   . ARG B 1 144 ? 65.27882  -35.39159 -22.01894 1.000 46.13570  ? 144 ARG B O   1 
ATOM   3649 C  CB  . ARG B 1 144 ? 62.63776  -33.74286 -22.97860 1.000 44.20176  ? 144 ARG B CB  1 
ATOM   3650 C  CG  . ARG B 1 144 ? 61.28353  -34.03070 -23.60692 1.000 53.67328  ? 144 ARG B CG  1 
ATOM   3651 C  CD  . ARG B 1 144 ? 61.04646  -33.22306 -24.87432 1.000 58.44769  ? 144 ARG B CD  1 
ATOM   3652 N  NE  . ARG B 1 144 ? 59.68029  -33.38806 -25.35741 1.000 56.81314  ? 144 ARG B NE  1 
ATOM   3653 C  CZ  . ARG B 1 144 ? 58.67641  -32.57327 -25.05986 1.000 60.52195  ? 144 ARG B CZ  1 
ATOM   3654 N  NH1 . ARG B 1 144 ? 58.85707  -31.49655 -24.31154 1.000 60.17526  ? 144 ARG B NH1 1 
ATOM   3655 N  NH2 . ARG B 1 144 ? 57.46023  -32.84561 -25.52428 1.000 68.02847  ? 144 ARG B NH2 1 
ATOM   3656 N  N   . ASN B 1 145 ? 64.83819  -33.69229 -20.60701 1.000 38.49708  ? 145 ASN B N   1 
ATOM   3657 C  CA  . ASN B 1 145 ? 66.21184  -33.65657 -20.11312 1.000 49.07139  ? 145 ASN B CA  1 
ATOM   3658 C  C   . ASN B 1 145 ? 66.56443  -34.95478 -19.40143 1.000 46.12475  ? 145 ASN B C   1 
ATOM   3659 O  O   . ASN B 1 145 ? 67.68529  -35.46098 -19.52807 1.000 49.42937  ? 145 ASN B O   1 
ATOM   3660 C  CB  . ASN B 1 145 ? 66.40786  -32.46743 -19.17157 1.000 44.35209  ? 145 ASN B CB  1 
ATOM   3661 C  CG  . ASN B 1 145 ? 66.21990  -31.13134 -19.86602 1.000 51.60419  ? 145 ASN B CG  1 
ATOM   3662 O  OD1 . ASN B 1 145 ? 66.32475  -31.03148 -21.08856 1.000 50.38006  ? 145 ASN B OD1 1 
ATOM   3663 N  ND2 . ASN B 1 145 ? 65.95410  -30.09265 -19.08371 1.000 48.57653  ? 145 ASN B ND2 1 
ATOM   3664 N  N   . TYR B 1 146 ? 65.61144  -35.50583 -18.64995 1.000 43.14715  ? 146 TYR B N   1 
ATOM   3665 C  CA  . TYR B 1 146 ? 65.82955  -36.76178 -17.94157 1.000 45.08681  ? 146 TYR B CA  1 
ATOM   3666 C  C   . TYR B 1 146 ? 66.08794  -37.90505 -18.91644 1.000 47.00277  ? 146 TYR B C   1 
ATOM   3667 O  O   . TYR B 1 146 ? 67.09085  -38.61909 -18.79966 1.000 42.29159  ? 146 TYR B O   1 
ATOM   3668 C  CB  . TYR B 1 146 ? 64.61494  -37.04064 -17.05469 1.000 41.14285  ? 146 TYR B CB  1 
ATOM   3669 C  CG  . TYR B 1 146 ? 64.55369  -38.38715 -16.37125 1.000 42.43362  ? 146 TYR B CG  1 
ATOM   3670 C  CD1 . TYR B 1 146 ? 65.22276  -38.61499 -15.17559 1.000 44.25464  ? 146 TYR B CD1 1 
ATOM   3671 C  CD2 . TYR B 1 146 ? 63.77483  -39.41385 -16.89129 1.000 43.04752  ? 146 TYR B CD2 1 
ATOM   3672 C  CE1 . TYR B 1 146 ? 65.14412  -39.84385 -14.53160 1.000 41.55974  ? 146 TYR B CE1 1 
ATOM   3673 C  CE2 . TYR B 1 146 ? 63.68920  -40.64313 -16.25662 1.000 48.38423  ? 146 TYR B CE2 1 
ATOM   3674 C  CZ  . TYR B 1 146 ? 64.37484  -40.85231 -15.07653 1.000 49.24675  ? 146 TYR B CZ  1 
ATOM   3675 O  OH  . TYR B 1 146 ? 64.29364  -42.07283 -14.44329 1.000 56.87921  ? 146 TYR B OH  1 
ATOM   3676 N  N   . PHE B 1 147 ? 65.19868  -38.08345 -19.89977 1.000 43.20323  ? 147 PHE B N   1 
ATOM   3677 C  CA  . PHE B 1 147 ? 65.37808  -39.16111 -20.87027 1.000 43.67704  ? 147 PHE B CA  1 
ATOM   3678 C  C   . PHE B 1 147 ? 66.62806  -38.94715 -21.71428 1.000 44.19028  ? 147 PHE B C   1 
ATOM   3679 O  O   . PHE B 1 147 ? 67.35018  -39.90498 -22.01663 1.000 44.32298  ? 147 PHE B O   1 
ATOM   3680 C  CB  . PHE B 1 147 ? 64.14572  -39.28238 -21.76745 1.000 43.78031  ? 147 PHE B CB  1 
ATOM   3681 C  CG  . PHE B 1 147 ? 62.89464  -39.66264 -21.03082 1.000 47.63612  ? 147 PHE B CG  1 
ATOM   3682 C  CD1 . PHE B 1 147 ? 62.82028  -40.86206 -20.34221 1.000 46.68066  ? 147 PHE B CD1 1 
ATOM   3683 C  CD2 . PHE B 1 147 ? 61.78848  -38.82694 -21.03422 1.000 43.23558  ? 147 PHE B CD2 1 
ATOM   3684 C  CE1 . PHE B 1 147 ? 61.67183  -41.21499 -19.66256 1.000 47.52732  ? 147 PHE B CE1 1 
ATOM   3685 C  CE2 . PHE B 1 147 ? 60.63576  -39.17733 -20.35593 1.000 46.24963  ? 147 PHE B CE2 1 
ATOM   3686 C  CZ  . PHE B 1 147 ? 60.57984  -40.37079 -19.66967 1.000 44.29814  ? 147 PHE B CZ  1 
ATOM   3687 N  N   . ASP B 1 148 ? 66.89559  -37.69838 -22.11274 1.000 45.42206  ? 148 ASP B N   1 
ATOM   3688 C  CA  . ASP B 1 148 ? 68.12116  -37.40614 -22.85013 1.000 46.51370  ? 148 ASP B CA  1 
ATOM   3689 C  C   . ASP B 1 148 ? 69.35429  -37.76751 -22.03780 1.000 51.08314  ? 148 ASP B C   1 
ATOM   3690 O  O   . ASP B 1 148 ? 70.37293  -38.18164 -22.60423 1.000 48.26076  ? 148 ASP B O   1 
ATOM   3691 C  CB  . ASP B 1 148 ? 68.17023  -35.92823 -23.24200 1.000 48.71344  ? 148 ASP B CB  1 
ATOM   3692 C  CG  . ASP B 1 148 ? 67.22406  -35.58908 -24.37773 1.000 54.78789  ? 148 ASP B CG  1 
ATOM   3693 O  OD1 . ASP B 1 148 ? 66.62188  -36.51923 -24.95391 1.000 58.53861  ? 148 ASP B OD1 1 
ATOM   3694 O  OD2 . ASP B 1 148 ? 67.08237  -34.38762 -24.69368 1.000 56.79479  ? 148 ASP B OD2 1 
ATOM   3695 N  N   . GLY B 1 149 ? 69.27908  -37.62551 -20.71284 1.000 49.51256  ? 149 GLY B N   1 
ATOM   3696 C  CA  . GLY B 1 149 ? 70.41972  -37.96015 -19.87992 1.000 47.78032  ? 149 GLY B CA  1 
ATOM   3697 C  C   . GLY B 1 149 ? 70.73940  -39.44273 -19.88608 1.000 47.77177  ? 149 GLY B C   1 
ATOM   3698 O  O   . GLY B 1 149 ? 71.90820  -39.83190 -19.80794 1.000 45.23577  ? 149 GLY B O   1 
ATOM   3699 N  N   . TYR B 1 150 ? 69.70853  -40.29100 -19.96236 1.000 45.08791  ? 150 TYR B N   1 
ATOM   3700 C  CA  . TYR B 1 150 ? 69.94413  -41.73098 -20.03030 1.000 50.49359  ? 150 TYR B CA  1 
ATOM   3701 C  C   . TYR B 1 150 ? 70.70658  -42.10536 -21.29391 1.000 44.98665  ? 150 TYR B C   1 
ATOM   3702 O  O   . TYR B 1 150 ? 71.55086  -43.00856 -21.27428 1.000 45.66526  ? 150 TYR B O   1 
ATOM   3703 C  CB  . TYR B 1 150 ? 68.61800  -42.48960 -19.95496 1.000 43.45205  ? 150 TYR B CB  1 
ATOM   3704 C  CG  . TYR B 1 150 ? 68.20168  -42.82033 -18.54046 1.000 48.89546  ? 150 TYR B CG  1 
ATOM   3705 C  CD1 . TYR B 1 150 ? 67.60583  -41.86371 -17.73014 1.000 48.52227  ? 150 TYR B CD1 1 
ATOM   3706 C  CD2 . TYR B 1 150 ? 68.41611  -44.08650 -18.01046 1.000 50.48285  ? 150 TYR B CD2 1 
ATOM   3707 C  CE1 . TYR B 1 150 ? 67.23167  -42.15927 -16.43069 1.000 51.48232  ? 150 TYR B CE1 1 
ATOM   3708 C  CE2 . TYR B 1 150 ? 68.04592  -44.39110 -16.71377 1.000 48.86771  ? 150 TYR B CE2 1 
ATOM   3709 C  CZ  . TYR B 1 150 ? 67.45373  -43.42462 -15.92963 1.000 50.40611  ? 150 TYR B CZ  1 
ATOM   3710 O  OH  . TYR B 1 150 ? 67.08327  -43.72735 -14.63954 1.000 54.92782  ? 150 TYR B OH  1 
ATOM   3711 N  N   . VAL B 1 151 ? 70.42565  -41.41981 -22.40327 1.000 46.98593  ? 151 VAL B N   1 
ATOM   3712 C  CA  . VAL B 1 151 ? 71.16512  -41.67453 -23.63531 1.000 44.71359  ? 151 VAL B CA  1 
ATOM   3713 C  C   . VAL B 1 151 ? 72.61859  -41.24295 -23.48134 1.000 48.15186  ? 151 VAL B C   1 
ATOM   3714 O  O   . VAL B 1 151 ? 73.53498  -41.91492 -23.97002 1.000 48.84134  ? 151 VAL B O   1 
ATOM   3715 C  CB  . VAL B 1 151 ? 70.48354  -40.96838 -24.82247 1.000 50.69261  ? 151 VAL B CB  1 
ATOM   3716 C  CG1 . VAL B 1 151 ? 71.21767  -41.27517 -26.12525 1.000 46.34276  ? 151 VAL B CG1 1 
ATOM   3717 C  CG2 . VAL B 1 151 ? 69.02125  -41.37718 -24.91573 1.000 41.58818  ? 151 VAL B CG2 1 
ATOM   3718 N  N   . ASP B 1 152 ? 72.85530  -40.12407 -22.78921 1.000 48.69388  ? 152 ASP B N   1 
ATOM   3719 C  CA  . ASP B 1 152 ? 74.22383  -39.65776 -22.58313 1.000 46.42769  ? 152 ASP B CA  1 
ATOM   3720 C  C   . ASP B 1 152 ? 75.02439  -40.63917 -21.73541 1.000 49.84156  ? 152 ASP B C   1 
ATOM   3721 O  O   . ASP B 1 152 ? 76.20935  -40.87295 -21.99903 1.000 50.33239  ? 152 ASP B O   1 
ATOM   3722 C  CB  . ASP B 1 152 ? 74.22177  -38.27444 -21.93178 1.000 55.23060  ? 152 ASP B CB  1 
ATOM   3723 C  CG  . ASP B 1 152 ? 73.67012  -37.19813 -22.84539 1.000 55.72100  ? 152 ASP B CG  1 
ATOM   3724 O  OD1 . ASP B 1 152 ? 73.58271  -37.44217 -24.06705 1.000 64.39325  ? 152 ASP B OD1 1 
ATOM   3725 O  OD2 . ASP B 1 152 ? 73.32994  -36.10660 -22.34194 1.000 58.52228  ? 152 ASP B OD2 1 
ATOM   3726 N  N   . GLU B 1 153 ? 74.39837  -41.22235 -20.70903 1.000 46.48806  ? 153 GLU B N   1 
ATOM   3727 C  CA  . GLU B 1 153 ? 75.10615  -42.19515 -19.88123 1.000 46.21340  ? 153 GLU B CA  1 
ATOM   3728 C  C   . GLU B 1 153 ? 75.43688  -43.45803 -20.66912 1.000 46.74711  ? 153 GLU B C   1 
ATOM   3729 O  O   . GLU B 1 153 ? 76.52318  -44.02596 -20.50995 1.000 43.02869  ? 153 GLU B O   1 
ATOM   3730 C  CB  . GLU B 1 153 ? 74.28480  -42.52980 -18.63534 1.000 49.61061  ? 153 GLU B CB  1 
ATOM   3731 C  CG  . GLU B 1 153 ? 74.25137  -41.40457 -17.61052 1.000 55.63497  ? 153 GLU B CG  1 
ATOM   3732 C  CD  . GLU B 1 153 ? 73.62336  -41.81729 -16.29492 1.000 66.98874  ? 153 GLU B CD  1 
ATOM   3733 O  OE1 . GLU B 1 153 ? 73.10138  -42.94926 -16.20820 1.000 73.88148  ? 153 GLU B OE1 1 
ATOM   3734 O  OE2 . GLU B 1 153 ? 73.65281  -41.00618 -15.34486 1.000 69.30358  ? 153 GLU B OE2 1 
ATOM   3735 N  N   . ALA B 1 154 ? 74.51714  -43.91097 -21.52648 1.000 43.14317  ? 154 ALA B N   1 
ATOM   3736 C  CA  . ALA B 1 154 ? 74.81193  -45.05439 -22.38443 1.000 48.62372  ? 154 ALA B CA  1 
ATOM   3737 C  C   . ALA B 1 154 ? 75.94536  -44.73572 -23.35239 1.000 52.02447  ? 154 ALA B C   1 
ATOM   3738 O  O   . ALA B 1 154 ? 76.77770  -45.60007 -23.65032 1.000 50.94528  ? 154 ALA B O   1 
ATOM   3739 C  CB  . ALA B 1 154 ? 73.55786  -45.48145 -23.14770 1.000 45.33957  ? 154 ALA B CB  1 
ATOM   3740 N  N   . GLU B 1 155 ? 75.99403  -43.49719 -23.85193 1.000 48.90750  ? 155 GLU B N   1 
ATOM   3741 C  CA  . GLU B 1 155 ? 77.09538  -43.08169 -24.71600 1.000 48.99855  ? 155 GLU B CA  1 
ATOM   3742 C  C   . GLU B 1 155 ? 78.42843  -43.18434 -23.99059 1.000 50.61978  ? 155 GLU B C   1 
ATOM   3743 O  O   . GLU B 1 155 ? 79.41694  -43.67321 -24.54895 1.000 54.17364  ? 155 GLU B O   1 
ATOM   3744 C  CB  . GLU B 1 155 ? 76.87359  -41.65070 -25.20779 1.000 55.52024  ? 155 GLU B CB  1 
ATOM   3745 C  CG  . GLU B 1 155 ? 75.98217  -41.52686 -26.42900 1.000 64.50933  ? 155 GLU B CG  1 
ATOM   3746 C  CD  . GLU B 1 155 ? 75.89495  -40.10133 -26.93820 1.000 74.11242  ? 155 GLU B CD  1 
ATOM   3747 O  OE1 . GLU B 1 155 ? 76.71030  -39.26249 -26.49782 1.000 73.68775  ? 155 GLU B OE1 1 
ATOM   3748 O  OE2 . GLU B 1 155 ? 75.01171  -39.81813 -27.77583 1.000 80.99464  ? 155 GLU B OE2 1 
ATOM   3749 N  N   . SER B 1 156 ? 78.47541  -42.71352 -22.74268 1.000 46.61082  ? 156 SER B N   1 
ATOM   3750 C  CA  . SER B 1 156 ? 79.71996  -42.75173 -21.98271 1.000 50.03777  ? 156 SER B CA  1 
ATOM   3751 C  C   . SER B 1 156 ? 80.20502  -44.18265 -21.78820 1.000 52.37007  ? 156 SER B C   1 
ATOM   3752 O  O   . SER B 1 156 ? 81.40070  -44.46612 -21.92892 1.000 50.81441  ? 156 SER B O   1 
ATOM   3753 C  CB  . SER B 1 156 ? 79.52857  -42.05879 -20.63341 1.000 47.73434  ? 156 SER B CB  1 
ATOM   3754 O  OG  . SER B 1 156 ? 80.69011  -42.17266 -19.83169 1.000 55.13818  ? 156 SER B OG  1 
ATOM   3755 N  N   . ARG B 1 157 ? 79.29132  -45.10077 -21.46770 1.000 51.27904  ? 157 ARG B N   1 
ATOM   3756 C  CA  . ARG B 1 157 ? 79.68599  -46.49466 -21.29518 1.000 55.45415  ? 157 ARG B CA  1 
ATOM   3757 C  C   . ARG B 1 157 ? 80.10128  -47.11504 -22.62189 1.000 58.07773  ? 157 ARG B C   1 
ATOM   3758 O  O   . ARG B 1 157 ? 81.06151  -47.89218 -22.67686 1.000 63.76179  ? 157 ARG B O   1 
ATOM   3759 C  CB  . ARG B 1 157 ? 78.54481  -47.29311 -20.66402 1.000 54.40931  ? 157 ARG B CB  1 
ATOM   3760 C  CG  . ARG B 1 157 ? 78.10534  -46.77302 -19.30871 1.000 53.12685  ? 157 ARG B CG  1 
ATOM   3761 C  CD  . ARG B 1 157 ? 77.15900  -47.73779 -18.61119 1.000 60.17328  ? 157 ARG B CD  1 
ATOM   3762 N  NE  . ARG B 1 157 ? 76.66049  -47.17993 -17.36001 1.000 62.25571  ? 157 ARG B NE  1 
ATOM   3763 C  CZ  . ARG B 1 157 ? 75.47150  -46.61129 -17.21504 1.000 61.94746  ? 157 ARG B CZ  1 
ATOM   3764 N  NH1 . ARG B 1 157 ? 74.60613  -46.55179 -18.21449 1.000 59.42864  ? 157 ARG B NH1 1 
ATOM   3765 N  NH2 . ARG B 1 157 ? 75.14053  -46.09073 -16.03712 1.000 64.87971  ? 157 ARG B NH2 1 
ATOM   3766 N  N   . PHE B 1 158 ? 79.39693  -46.77113 -23.70247 1.000 58.20051  ? 158 PHE B N   1 
ATOM   3767 C  CA  . PHE B 1 158 ? 79.67233  -47.37807 -25.00062 1.000 54.54428  ? 158 PHE B CA  1 
ATOM   3768 C  C   . PHE B 1 158 ? 81.08598  -47.05835 -25.47226 1.000 60.23786  ? 158 PHE B C   1 
ATOM   3769 O  O   . PHE B 1 158 ? 81.83632  -47.95431 -25.87558 1.000 66.35136  ? 158 PHE B O   1 
ATOM   3770 C  CB  . PHE B 1 158 ? 78.63964  -46.90402 -26.02351 1.000 54.59926  ? 158 PHE B CB  1 
ATOM   3771 C  CG  . PHE B 1 158 ? 78.83351  -47.48346 -27.39749 1.000 61.88762  ? 158 PHE B CG  1 
ATOM   3772 C  CD1 . PHE B 1 158 ? 78.41835  -48.77478 -27.68416 1.000 63.08169  ? 158 PHE B CD1 1 
ATOM   3773 C  CD2 . PHE B 1 158 ? 79.42286  -46.73529 -28.40571 1.000 63.53338  ? 158 PHE B CD2 1 
ATOM   3774 C  CE1 . PHE B 1 158 ? 78.59292  -49.31202 -28.94919 1.000 68.84179  ? 158 PHE B CE1 1 
ATOM   3775 C  CE2 . PHE B 1 158 ? 79.60014  -47.26678 -29.67314 1.000 65.83288  ? 158 PHE B CE2 1 
ATOM   3776 C  CZ  . PHE B 1 158 ? 79.18400  -48.55627 -29.94444 1.000 58.85925  ? 158 PHE B CZ  1 
ATOM   3777 N  N   . TRP B 1 159 ? 81.47011  -45.78544 -25.42323 1.000 59.04260  ? 159 TRP B N   1 
ATOM   3778 C  CA  . TRP B 1 159 ? 82.77807  -45.35545 -25.90067 1.000 57.87189  ? 159 TRP B CA  1 
ATOM   3779 C  C   . TRP B 1 159 ? 83.88378  -45.53754 -24.86929 1.000 62.04384  ? 159 TRP B C   1 
ATOM   3780 O  O   . TRP B 1 159 ? 85.02364  -45.14269 -25.14049 1.000 59.35580  ? 159 TRP B O   1 
ATOM   3781 C  CB  . TRP B 1 159 ? 82.72051  -43.89063 -26.34071 1.000 60.97870  ? 159 TRP B CB  1 
ATOM   3782 C  CG  . TRP B 1 159 ? 81.82777  -43.66327 -27.52172 1.000 69.05549  ? 159 TRP B CG  1 
ATOM   3783 C  CD1 . TRP B 1 159 ? 80.61464  -43.03943 -27.52550 1.000 66.03429  ? 159 TRP B CD1 1 
ATOM   3784 C  CD2 . TRP B 1 159 ? 82.07440  -44.06966 -28.87405 1.000 68.99239  ? 159 TRP B CD2 1 
ATOM   3785 N  NE1 . TRP B 1 159 ? 80.09265  -43.02647 -28.79695 1.000 61.80476  ? 159 TRP B NE1 1 
ATOM   3786 C  CE2 . TRP B 1 159 ? 80.96913  -43.65381 -29.64308 1.000 70.35078  ? 159 TRP B CE2 1 
ATOM   3787 C  CE3 . TRP B 1 159 ? 83.12368  -44.74312 -29.50936 1.000 73.78014  ? 159 TRP B CE3 1 
ATOM   3788 C  CZ2 . TRP B 1 159 ? 80.88262  -43.88886 -31.01551 1.000 75.70460  ? 159 TRP B CZ2 1 
ATOM   3789 C  CZ3 . TRP B 1 159 ? 83.03531  -44.97610 -30.87273 1.000 66.15241  ? 159 TRP B CZ3 1 
ATOM   3790 C  CH2 . TRP B 1 159 ? 81.92299  -44.54940 -31.60977 1.000 70.50801  ? 159 TRP B CH2 1 
ATOM   3791 N  N   . ASN B 1 160 ? 83.57994  -46.13194 -23.71473 1.000 59.52897  ? 160 ASN B N   1 
ATOM   3792 C  CA  . ASN B 1 160 ? 84.53903  -46.27266 -22.61962 1.000 67.90580  ? 160 ASN B CA  1 
ATOM   3793 C  C   . ASN B 1 160 ? 85.20970  -44.93636 -22.31347 1.000 68.20382  ? 160 ASN B C   1 
ATOM   3794 O  O   . ASN B 1 160 ? 86.43115  -44.83536 -22.17908 1.000 70.02140  ? 160 ASN B O   1 
ATOM   3795 C  CB  . ASN B 1 160 ? 85.57599  -47.35269 -22.92942 1.000 72.70269  ? 160 ASN B CB  1 
ATOM   3796 C  CG  . ASN B 1 160 ? 85.04825  -48.75330 -22.68497 1.000 82.61343  ? 160 ASN B CG  1 
ATOM   3797 O  OD1 . ASN B 1 160 ? 84.28531  -48.98891 -21.74543 1.000 81.59533  ? 160 ASN B OD1 1 
ATOM   3798 N  ND2 . ASN B 1 160 ? 85.45484  -49.69324 -23.53043 1.000 86.80445  ? 160 ASN B ND2 1 
ATOM   3799 N  N   . ALA B 1 161 ? 84.38402  -43.89225 -22.21946 1.000 63.16175  ? 161 ALA B N   1 
ATOM   3800 C  CA  . ALA B 1 161 ? 84.83191  -42.52625 -21.96320 1.000 63.16239  ? 161 ALA B CA  1 
ATOM   3801 C  C   . ALA B 1 161 ? 84.24508  -42.06891 -20.63217 1.000 56.36044  ? 161 ALA B C   1 
ATOM   3802 O  O   . ALA B 1 161 ? 83.22738  -41.36034 -20.60097 1.000 60.10042  ? 161 ALA B O   1 
ATOM   3803 C  CB  . ALA B 1 161 ? 84.42408  -41.59040 -23.09952 1.000 58.92625  ? 161 ALA B CB  1 
ATOM   3804 N  N   . PRO B 1 162 ? 84.85689  -42.45139 -19.51460 1.000 57.81769  ? 162 PRO B N   1 
ATOM   3805 C  CA  . PRO B 1 162 ? 84.33139  -42.04148 -18.20895 1.000 60.86684  ? 162 PRO B CA  1 
ATOM   3806 C  C   . PRO B 1 162 ? 84.57305  -40.56409 -17.93957 1.000 59.67267  ? 162 PRO B C   1 
ATOM   3807 O  O   . PRO B 1 162 ? 85.48450  -39.93889 -18.48613 1.000 60.11277  ? 162 PRO B O   1 
ATOM   3808 C  CB  . PRO B 1 162 ? 85.11464  -42.91359 -17.22365 1.000 56.13498  ? 162 PRO B CB  1 
ATOM   3809 C  CG  . PRO B 1 162 ? 86.41056  -43.17013 -17.91925 1.000 60.43936  ? 162 PRO B CG  1 
ATOM   3810 C  CD  . PRO B 1 162 ? 86.07855  -43.26624 -19.38932 1.000 62.53474  ? 162 PRO B CD  1 
ATOM   3811 N  N   . CYS B 1 163 ? 83.72916  -40.00863 -17.07228 1.000 56.95538  ? 163 CYS B N   1 
ATOM   3812 C  CA  . CYS B 1 163 ? 83.90891  -38.63223 -16.63243 1.000 55.41100  ? 163 CYS B CA  1 
ATOM   3813 C  C   . CYS B 1 163 ? 85.23138  -38.49716 -15.89015 1.000 57.46799  ? 163 CYS B C   1 
ATOM   3814 O  O   . CYS B 1 163 ? 85.56046  -39.31905 -15.03023 1.000 51.66630  ? 163 CYS B O   1 
ATOM   3815 C  CB  . CYS B 1 163 ? 82.74717  -38.20928 -15.73261 1.000 46.63784  ? 163 CYS B CB  1 
ATOM   3816 S  SG  . CYS B 1 163 ? 81.10825  -38.45424 -16.45878 1.000 60.64928  ? 163 CYS B SG  1 
ATOM   3817 N  N   . ASP B 1 164 ? 86.00130  -37.46615 -16.23392 1.000 57.06556  ? 164 ASP B N   1 
ATOM   3818 C  CA  . ASP B 1 164 ? 87.29938  -37.24254 -15.61243 1.000 60.41787  ? 164 ASP B CA  1 
ATOM   3819 C  C   . ASP B 1 164 ? 87.28562  -36.08459 -14.62341 1.000 56.46897  ? 164 ASP B C   1 
ATOM   3820 O  O   . ASP B 1 164 ? 88.35482  -35.62692 -14.20807 1.000 62.98495  ? 164 ASP B O   1 
ATOM   3821 C  CB  . ASP B 1 164 ? 88.37623  -37.02071 -16.68052 1.000 66.24729  ? 164 ASP B CB  1 
ATOM   3822 C  CG  . ASP B 1 164 ? 88.12251  -35.79112 -17.53091 1.000 77.82755  ? 164 ASP B CG  1 
ATOM   3823 O  OD1 . ASP B 1 164 ? 88.24802  -34.66202 -17.00955 1.000 81.38135  ? 164 ASP B OD1 1 
ATOM   3824 O  OD2 . ASP B 1 164 ? 87.81464  -35.95465 -18.73019 1.000 88.61737  ? 164 ASP B OD2 1 
ATOM   3825 N  N   . SER B 1 165 ? 86.10664  -35.60590 -14.23251 1.000 53.23387  ? 165 SER B N   1 
ATOM   3826 C  CA  . SER B 1 165 ? 86.00005  -34.55943 -13.22525 1.000 51.26444  ? 165 SER B CA  1 
ATOM   3827 C  C   . SER B 1 165 ? 84.57767  -34.53880 -12.68986 1.000 44.51840  ? 165 SER B C   1 
ATOM   3828 O  O   . SER B 1 165 ? 83.63946  -34.99802 -13.34713 1.000 47.51837  ? 165 SER B O   1 
ATOM   3829 C  CB  . SER B 1 165 ? 86.37645  -33.18382 -13.78748 1.000 52.96277  ? 165 SER B CB  1 
ATOM   3830 O  OG  . SER B 1 165 ? 85.44266  -32.76109 -14.76442 1.000 52.03358  ? 165 SER B OG  1 
ATOM   3831 N  N   . ALA B 1 166 ? 84.43248  -33.99539 -11.48015 1.000 42.47502  ? 166 ALA B N   1 
ATOM   3832 C  CA  . ALA B 1 166 ? 83.10295  -33.81985 -10.90743 1.000 49.83295  ? 166 ALA B CA  1 
ATOM   3833 C  C   . ALA B 1 166 ? 82.22459  -32.95689 -11.80596 1.000 56.27351  ? 166 ALA B C   1 
ATOM   3834 O  O   . ALA B 1 166 ? 81.02760  -33.22470 -11.95956 1.000 54.93776  ? 166 ALA B O   1 
ATOM   3835 C  CB  . ALA B 1 166 ? 83.21258  -33.20512 -9.51293  1.000 40.07354  ? 166 ALA B CB  1 
ATOM   3836 N  N   . ALA B 1 167 ? 82.81294  -31.93246 -12.43118 1.000 55.04647  ? 167 ALA B N   1 
ATOM   3837 C  CA  . ALA B 1 167 ? 82.03802  -30.99376 -13.23881 1.000 47.55616  ? 167 ALA B CA  1 
ATOM   3838 C  C   . ALA B 1 167 ? 81.40525  -31.68133 -14.44359 1.000 55.59603  ? 167 ALA B C   1 
ATOM   3839 O  O   . ALA B 1 167 ? 80.20582  -31.52278 -14.70132 1.000 56.52020  ? 167 ALA B O   1 
ATOM   3840 C  CB  . ALA B 1 167 ? 82.92816  -29.83390 -13.68503 1.000 56.53155  ? 167 ALA B CB  1 
ATOM   3841 N  N   . GLN B 1 168 ? 82.20085  -32.44021 -15.20516 1.000 51.54402  ? 168 GLN B N   1 
ATOM   3842 C  CA  . GLN B 1 168 ? 81.64293  -33.20125 -16.32076 1.000 51.71795  ? 168 GLN B CA  1 
ATOM   3843 C  C   . GLN B 1 168 ? 80.55906  -34.15761 -15.84621 1.000 54.07605  ? 168 GLN B C   1 
ATOM   3844 O  O   . GLN B 1 168 ? 79.54217  -34.34737 -16.52542 1.000 53.24716  ? 168 GLN B O   1 
ATOM   3845 C  CB  . GLN B 1 168 ? 82.73829  -33.99044 -17.03499 1.000 58.77827  ? 168 GLN B CB  1 
ATOM   3846 C  CG  . GLN B 1 168 ? 83.84955  -33.16822 -17.62652 1.000 66.05114  ? 168 GLN B CG  1 
ATOM   3847 C  CD  . GLN B 1 168 ? 84.88243  -34.03614 -18.30835 1.000 72.59073  ? 168 GLN B CD  1 
ATOM   3848 O  OE1 . GLN B 1 168 ? 86.06533  -33.70053 -18.34216 1.000 78.68292  ? 168 GLN B OE1 1 
ATOM   3849 N  NE2 . GLN B 1 168 ? 84.43889  -35.16359 -18.85840 1.000 65.97945  ? 168 GLN B NE2 1 
ATOM   3850 N  N   . TYR B 1 169 ? 80.77096  -34.78215 -14.68684 1.000 51.89461  ? 169 TYR B N   1 
ATOM   3851 C  CA  . TYR B 1 169 ? 79.80875  -35.74577 -14.16713 1.000 47.64080  ? 169 TYR B CA  1 
ATOM   3852 C  C   . TYR B 1 169 ? 78.48583  -35.07305 -13.83033 1.000 46.66529  ? 169 TYR B C   1 
ATOM   3853 O  O   . TYR B 1 169 ? 77.41533  -35.54281 -14.23485 1.000 45.27848  ? 169 TYR B O   1 
ATOM   3854 C  CB  . TYR B 1 169 ? 80.39314  -36.43590 -12.93755 1.000 47.68194  ? 169 TYR B CB  1 
ATOM   3855 C  CG  . TYR B 1 169 ? 79.47090  -37.43229 -12.28551 1.000 43.77560  ? 169 TYR B CG  1 
ATOM   3856 C  CD1 . TYR B 1 169 ? 78.89985  -38.46160 -13.02008 1.000 46.73968  ? 169 TYR B CD1 1 
ATOM   3857 C  CD2 . TYR B 1 169 ? 79.19440  -37.36235 -10.92674 1.000 44.07442  ? 169 TYR B CD2 1 
ATOM   3858 C  CE1 . TYR B 1 169 ? 78.06451  -39.38301 -12.42354 1.000 46.96060  ? 169 TYR B CE1 1 
ATOM   3859 C  CE2 . TYR B 1 169 ? 78.36126  -38.27797 -10.32175 1.000 44.64897  ? 169 TYR B CE2 1 
ATOM   3860 C  CZ  . TYR B 1 169 ? 77.80024  -39.28653 -11.07407 1.000 41.63383  ? 169 TYR B CZ  1 
ATOM   3861 O  OH  . TYR B 1 169 ? 76.96942  -40.19995 -10.47604 1.000 46.51692  ? 169 TYR B OH  1 
ATOM   3862 N  N   . LEU B 1 170 ? 78.54538  -33.96143 -13.09266 1.000 42.91349  ? 170 LEU B N   1 
ATOM   3863 C  CA  . LEU B 1 170 ? 77.32877  -33.27245 -12.67306 1.000 49.40502  ? 170 LEU B CA  1 
ATOM   3864 C  C   . LEU B 1 170 ? 76.51904  -32.78310 -13.86768 1.000 50.10602  ? 170 LEU B C   1 
ATOM   3865 O  O   . LEU B 1 170 ? 75.28507  -32.85001 -13.85543 1.000 50.80107  ? 170 LEU B O   1 
ATOM   3866 C  CB  . LEU B 1 170 ? 77.68300  -32.10518 -11.75370 1.000 48.96628  ? 170 LEU B CB  1 
ATOM   3867 C  CG  . LEU B 1 170 ? 78.31311  -32.48465 -10.41306 1.000 53.23328  ? 170 LEU B CG  1 
ATOM   3868 C  CD1 . LEU B 1 170 ? 79.00160  -31.27886 -9.79209  1.000 50.62015  ? 170 LEU B CD1 1 
ATOM   3869 C  CD2 . LEU B 1 170 ? 77.26624  -33.05681 -9.46484  1.000 48.69308  ? 170 LEU B CD2 1 
ATOM   3870 N  N   . ALA B 1 171 ? 77.19449  -32.29208 -14.91242 1.000 50.31473  ? 171 ALA B N   1 
ATOM   3871 C  CA  . ALA B 1 171 ? 76.48701  -31.82540 -16.10324 1.000 52.39622  ? 171 ALA B CA  1 
ATOM   3872 C  C   . ALA B 1 171 ? 75.61796  -32.91998 -16.70967 1.000 55.80628  ? 171 ALA B C   1 
ATOM   3873 O  O   . ALA B 1 171 ? 74.62717  -32.62526 -17.38809 1.000 60.10166  ? 171 ALA B O   1 
ATOM   3874 C  CB  . ALA B 1 171 ? 77.48312  -31.30405 -17.13899 1.000 53.51730  ? 171 ALA B CB  1 
ATOM   3875 N  N   . MET B 1 172 ? 75.96271  -34.18152 -16.46684 1.000 54.94300  ? 172 MET B N   1 
ATOM   3876 C  CA  . MET B 1 172 ? 75.17644  -35.31664 -16.92991 1.000 48.30530  ? 172 MET B CA  1 
ATOM   3877 C  C   . MET B 1 172 ? 74.24697  -35.85837 -15.84388 1.000 53.35649  ? 172 MET B C   1 
ATOM   3878 O  O   . MET B 1 172 ? 73.05236  -36.05822 -16.08818 1.000 46.00728  ? 172 MET B O   1 
ATOM   3879 C  CB  . MET B 1 172 ? 76.11569  -36.41773 -17.42510 1.000 49.05803  ? 172 MET B CB  1 
ATOM   3880 C  CG  . MET B 1 172 ? 75.42136  -37.66948 -17.91598 1.000 53.63108  ? 172 MET B CG  1 
ATOM   3881 S  SD  . MET B 1 172 ? 76.61268  -38.93250 -18.41286 1.000 63.30794  ? 172 MET B SD  1 
ATOM   3882 C  CE  . MET B 1 172 ? 77.35635  -39.35259 -16.83632 1.000 54.43398  ? 172 MET B CE  1 
ATOM   3883 N  N   . ARG B 1 173 ? 74.77560  -36.09234 -14.63850 1.000 45.90475  ? 173 ARG B N   1 
ATOM   3884 C  CA  . ARG B 1 173 ? 73.98869  -36.73440 -13.58960 1.000 43.93812  ? 173 ARG B CA  1 
ATOM   3885 C  C   . ARG B 1 173 ? 72.91105  -35.81898 -13.01694 1.000 45.37729  ? 173 ARG B C   1 
ATOM   3886 O  O   . ARG B 1 173 ? 71.94883  -36.31458 -12.41896 1.000 46.54091  ? 173 ARG B O   1 
ATOM   3887 C  CB  . ARG B 1 173 ? 74.90367  -37.22518 -12.46232 1.000 47.04587  ? 173 ARG B CB  1 
ATOM   3888 C  CG  . ARG B 1 173 ? 74.21363  -38.13177 -11.43987 1.000 46.25866  ? 173 ARG B CG  1 
ATOM   3889 C  CD  . ARG B 1 173 ? 74.14577  -39.57137 -11.92540 1.000 56.88363  ? 173 ARG B CD  1 
ATOM   3890 N  NE  . ARG B 1 173 ? 73.00264  -40.30279 -11.38887 1.000 64.23114  ? 173 ARG B NE  1 
ATOM   3891 C  CZ  . ARG B 1 173 ? 72.91203  -40.76952 -10.14868 1.000 71.39350  ? 173 ARG B CZ  1 
ATOM   3892 N  NH1 . ARG B 1 173 ? 73.85841  -40.54609 -9.24784  1.000 61.63682  ? 173 ARG B NH1 1 
ATOM   3893 N  NH2 . ARG B 1 173 ? 71.84145  -41.47628 -9.79993  1.000 71.85882  ? 173 ARG B NH2 1 
ATOM   3894 N  N   . ARG B 1 174 ? 73.03707  -34.50022 -13.18511 1.000 43.00729  ? 174 ARG B N   1 
ATOM   3895 C  CA  . ARG B 1 174 ? 71.99313  -33.61097 -12.68619 1.000 40.94687  ? 174 ARG B CA  1 
ATOM   3896 C  C   . ARG B 1 174 ? 70.66687  -33.85452 -13.38858 1.000 45.02012  ? 174 ARG B C   1 
ATOM   3897 O  O   . ARG B 1 174 ? 69.60690  -33.54950 -12.83090 1.000 46.85554  ? 174 ARG B O   1 
ATOM   3898 C  CB  . ARG B 1 174 ? 72.41658  -32.15269 -12.83590 1.000 44.57139  ? 174 ARG B CB  1 
ATOM   3899 C  CG  . ARG B 1 174 ? 73.28561  -31.65322 -11.68654 1.000 47.51049  ? 174 ARG B CG  1 
ATOM   3900 C  CD  . ARG B 1 174 ? 73.96609  -30.33100 -12.01501 1.000 46.55157  ? 174 ARG B CD  1 
ATOM   3901 N  NE  . ARG B 1 174 ? 74.72884  -29.83004 -10.87786 1.000 49.01770  ? 174 ARG B NE  1 
ATOM   3902 C  CZ  . ARG B 1 174 ? 75.64150  -28.87189 -10.95120 1.000 48.28724  ? 174 ARG B CZ  1 
ATOM   3903 N  NH1 . ARG B 1 174 ? 75.94178  -28.29178 -12.10127 1.000 52.86252  ? 174 ARG B NH1 1 
ATOM   3904 N  NH2 . ARG B 1 174 ? 76.27266  -28.49122 -9.84394  1.000 47.94969  ? 174 ARG B NH2 1 
ATOM   3905 N  N   . HIS B 1 175 ? 70.70102  -34.41760 -14.59586 1.000 44.10066  ? 175 HIS B N   1 
ATOM   3906 C  CA  . HIS B 1 175 ? 69.48180  -34.72075 -15.33341 1.000 45.76001  ? 175 HIS B CA  1 
ATOM   3907 C  C   . HIS B 1 175 ? 68.96636  -36.13042 -15.06123 1.000 43.53071  ? 175 HIS B C   1 
ATOM   3908 O  O   . HIS B 1 175 ? 67.75026  -36.33674 -14.99457 1.000 48.49170  ? 175 HIS B O   1 
ATOM   3909 C  CB  . HIS B 1 175 ? 69.71550  -34.53162 -16.83550 1.000 46.81511  ? 175 HIS B CB  1 
ATOM   3910 C  CG  . HIS B 1 175 ? 70.15666  -33.15038 -17.20836 1.000 48.80537  ? 175 HIS B CG  1 
ATOM   3911 N  ND1 . HIS B 1 175 ? 69.34774  -32.04472 -17.05738 1.000 49.83837  ? 175 HIS B ND1 1 
ATOM   3912 C  CD2 . HIS B 1 175 ? 71.32299  -32.69553 -17.72476 1.000 50.11321  ? 175 HIS B CD2 1 
ATOM   3913 C  CE1 . HIS B 1 175 ? 69.99691  -30.96820 -17.46395 1.000 50.04840  ? 175 HIS B CE1 1 
ATOM   3914 N  NE2 . HIS B 1 175 ? 71.19767  -31.33565 -17.87396 1.000 49.47452  ? 175 HIS B NE2 1 
ATOM   3915 N  N   . THR B 1 176 ? 69.86260  -37.10668 -14.89228 1.000 41.59051  ? 176 THR B N   1 
ATOM   3916 C  CA  . THR B 1 176 ? 69.43723  -38.49474 -14.73693 1.000 47.41536  ? 176 THR B CA  1 
ATOM   3917 C  C   . THR B 1 176 ? 69.01327  -38.84358 -13.31721 1.000 46.89036  ? 176 THR B C   1 
ATOM   3918 O  O   . THR B 1 176 ? 68.31436  -39.84542 -13.12973 1.000 47.38994  ? 176 THR B O   1 
ATOM   3919 C  CB  . THR B 1 176 ? 70.55002  -39.45245 -15.16623 1.000 49.28485  ? 176 THR B CB  1 
ATOM   3920 O  OG1 . THR B 1 176 ? 71.68096  -39.30194 -14.29941 1.000 49.04888  ? 176 THR B OG1 1 
ATOM   3921 C  CG2 . THR B 1 176 ? 70.96559  -39.16169 -16.58787 1.000 50.07156  ? 176 THR B CG2 1 
ATOM   3922 N  N   . ILE B 1 177 ? 69.42182  -38.05700 -12.31719 1.000 44.59376  ? 177 ILE B N   1 
ATOM   3923 C  CA  . ILE B 1 177 ? 69.02867  -38.33927 -10.94129 1.000 42.14886  ? 177 ILE B CA  1 
ATOM   3924 C  C   . ILE B 1 177 ? 67.52148  -38.19368 -10.75837 1.000 41.38479  ? 177 ILE B C   1 
ATOM   3925 O  O   . ILE B 1 177 ? 66.95089  -38.77235 -9.82724  1.000 43.79581  ? 177 ILE B O   1 
ATOM   3926 C  CB  . ILE B 1 177 ? 69.81888  -37.43131 -9.96773  1.000 43.60118  ? 177 ILE B CB  1 
ATOM   3927 C  CG1 . ILE B 1 177 ? 69.56443  -37.82732 -8.50748  1.000 49.03196  ? 177 ILE B CG1 1 
ATOM   3928 C  CG2 . ILE B 1 177 ? 69.48371  -35.96423 -10.19712 1.000 40.60712  ? 177 ILE B CG2 1 
ATOM   3929 C  CD1 . ILE B 1 177 ? 70.05220  -39.21767 -8.14909  1.000 40.26091  ? 177 ILE B CD1 1 
ATOM   3930 N  N   . GLY B 1 178 ? 66.85648  -37.44417 -11.63766 1.000 41.14326  ? 178 GLY B N   1 
ATOM   3931 C  CA  . GLY B 1 178 ? 65.40977  -37.33559 -11.60894 1.000 41.40020  ? 178 GLY B CA  1 
ATOM   3932 C  C   . GLY B 1 178 ? 64.83884  -36.47258 -10.50796 1.000 42.98885  ? 178 GLY B C   1 
ATOM   3933 O  O   . GLY B 1 178 ? 63.67317  -36.64815 -10.14124 1.000 40.56882  ? 178 GLY B O   1 
ATOM   3934 N  N   . VAL B 1 179 ? 65.61723  -35.52936 -9.97798  1.000 40.13862  ? 179 VAL B N   1 
ATOM   3935 C  CA  . VAL B 1 179 ? 65.14882  -34.72620 -8.85358  1.000 37.09399  ? 179 VAL B CA  1 
ATOM   3936 C  C   . VAL B 1 179 ? 64.15246  -33.66827 -9.31571  1.000 40.85306  ? 179 VAL B C   1 
ATOM   3937 O  O   . VAL B 1 179 ? 63.14637  -33.40867 -8.64405  1.000 41.84154  ? 179 VAL B O   1 
ATOM   3938 C  CB  . VAL B 1 179 ? 66.35046  -34.10062 -8.12534  1.000 40.76361  ? 179 VAL B CB  1 
ATOM   3939 C  CG1 . VAL B 1 179 ? 65.89349  -33.00457 -7.19422  1.000 39.98747  ? 179 VAL B CG1 1 
ATOM   3940 C  CG2 . VAL B 1 179 ? 67.10221  -35.17168 -7.36889  1.000 39.99416  ? 179 VAL B CG2 1 
ATOM   3941 N  N   . GLN B 1 180 ? 64.41080  -33.03701 -10.45939 1.000 39.61600  ? 180 GLN B N   1 
ATOM   3942 C  CA  . GLN B 1 180 ? 63.52508  -31.96707 -10.90777 1.000 43.59838  ? 180 GLN B CA  1 
ATOM   3943 C  C   . GLN B 1 180 ? 62.10259  -32.44533 -11.18974 1.000 45.02326  ? 180 GLN B C   1 
ATOM   3944 O  O   . GLN B 1 180 ? 61.16108  -31.76289 -10.75184 1.000 47.68664  ? 180 GLN B O   1 
ATOM   3945 C  CB  . GLN B 1 180 ? 64.13164  -31.26197 -12.12796 1.000 42.32701  ? 180 GLN B CB  1 
ATOM   3946 C  CG  . GLN B 1 180 ? 63.43014  -29.96461 -12.49081 1.000 40.27239  ? 180 GLN B CG  1 
ATOM   3947 C  CD  . GLN B 1 180 ? 63.31301  -29.01772 -11.30982 1.000 49.11619  ? 180 GLN B CD  1 
ATOM   3948 O  OE1 . GLN B 1 180 ? 64.31621  -28.56428 -10.75810 1.000 51.82781  ? 180 GLN B OE1 1 
ATOM   3949 N  NE2 . GLN B 1 180 ? 62.08237  -28.72065 -10.91131 1.000 48.99966  ? 180 GLN B NE2 1 
ATOM   3950 N  N   . PRO B 1 181 ? 61.86361  -33.56616 -11.88379 1.000 44.35715  ? 181 PRO B N   1 
ATOM   3951 C  CA  . PRO B 1 181 ? 60.47662  -34.04795 -11.99168 1.000 43.82001  ? 181 PRO B CA  1 
ATOM   3952 C  C   . PRO B 1 181 ? 59.89309  -34.45395 -10.65244 1.000 45.84928  ? 181 PRO B C   1 
ATOM   3953 O  O   . PRO B 1 181 ? 58.67211  -34.36698 -10.46717 1.000 45.34366  ? 181 PRO B O   1 
ATOM   3954 C  CB  . PRO B 1 181 ? 60.58495  -35.24286 -12.95079 1.000 40.58169  ? 181 PRO B CB  1 
ATOM   3955 C  CG  . PRO B 1 181 ? 61.85876  -35.02551 -13.69191 1.000 41.49372  ? 181 PRO B CG  1 
ATOM   3956 C  CD  . PRO B 1 181 ? 62.78088  -34.36948 -12.71061 1.000 43.43424  ? 181 PRO B CD  1 
ATOM   3957 N  N   . THR B 1 182 ? 60.73173  -34.89987 -9.71444  1.000 44.06932  ? 182 THR B N   1 
ATOM   3958 C  CA  . THR B 1 182 ? 60.25868  -35.17683 -8.36272  1.000 44.18116  ? 182 THR B CA  1 
ATOM   3959 C  C   . THR B 1 182 ? 59.74510  -33.90525 -7.69959  1.000 47.07386  ? 182 THR B C   1 
ATOM   3960 O  O   . THR B 1 182 ? 58.64876  -33.88694 -7.12911  1.000 46.73705  ? 182 THR B O   1 
ATOM   3961 C  CB  . THR B 1 182 ? 61.38047  -35.80141 -7.53052  1.000 43.06831  ? 182 THR B CB  1 
ATOM   3962 O  OG1 . THR B 1 182 ? 61.78134  -37.04769 -8.11445  1.000 43.71443  ? 182 THR B OG1 1 
ATOM   3963 C  CG2 . THR B 1 182 ? 60.91673  -36.03397 -6.10274  1.000 43.08323  ? 182 THR B CG2 1 
ATOM   3964 N  N   . VAL B 1 183 ? 60.52724  -32.82534 -7.77419  1.000 41.84627  ? 183 VAL B N   1 
ATOM   3965 C  CA  . VAL B 1 183 ? 60.09211  -31.54388 -7.22466  1.000 46.09334  ? 183 VAL B CA  1 
ATOM   3966 C  C   . VAL B 1 183 ? 58.85777  -31.03924 -7.96101  1.000 46.68123  ? 183 VAL B C   1 
ATOM   3967 O  O   . VAL B 1 183 ? 57.93678  -30.48333 -7.35040  1.000 47.87119  ? 183 VAL B O   1 
ATOM   3968 C  CB  . VAL B 1 183 ? 61.24237  -30.52088 -7.28267  1.000 41.05879  ? 183 VAL B CB  1 
ATOM   3969 C  CG1 . VAL B 1 183 ? 60.77961  -29.16663 -6.77075  1.000 44.29156  ? 183 VAL B CG1 1 
ATOM   3970 C  CG2 . VAL B 1 183 ? 62.43602  -31.01796 -6.48496  1.000 37.38834  ? 183 VAL B CG2 1 
ATOM   3971 N  N   . ASP B 1 184 ? 58.81896  -31.22561 -9.28298  1.000 47.18243  ? 184 ASP B N   1 
ATOM   3972 C  CA  . ASP B 1 184 ? 57.65892  -30.80952 -10.06646 1.000 50.99289  ? 184 ASP B CA  1 
ATOM   3973 C  C   . ASP B 1 184 ? 56.37846  -31.43993 -9.53449  1.000 49.13592  ? 184 ASP B C   1 
ATOM   3974 O  O   . ASP B 1 184 ? 55.36485  -30.75725 -9.35102  1.000 53.57398  ? 184 ASP B O   1 
ATOM   3975 C  CB  . ASP B 1 184 ? 57.85593  -31.17518 -11.53985 1.000 47.30718  ? 184 ASP B CB  1 
ATOM   3976 C  CG  . ASP B 1 184 ? 58.89099  -30.31060 -12.22455 1.000 46.37609  ? 184 ASP B CG  1 
ATOM   3977 O  OD1 . ASP B 1 184 ? 59.22600  -29.23419 -11.68612 1.000 49.37555  ? 184 ASP B OD1 1 
ATOM   3978 O  OD2 . ASP B 1 184 ? 59.36199  -30.70421 -13.31112 1.000 45.74464  ? 184 ASP B OD2 1 
ATOM   3979 N  N   . LEU B 1 185 ? 56.41106  -32.74889 -9.27185  1.000 49.67064  ? 185 LEU B N   1 
ATOM   3980 C  CA  . LEU B 1 185 ? 55.21519  -33.43212 -8.79165  1.000 49.54627  ? 185 LEU B CA  1 
ATOM   3981 C  C   . LEU B 1 185 ? 54.76351  -32.89869 -7.43814  1.000 48.83594  ? 185 LEU B C   1 
ATOM   3982 O  O   . LEU B 1 185 ? 53.56998  -32.95182 -7.12122  1.000 49.73771  ? 185 LEU B O   1 
ATOM   3983 C  CB  . LEU B 1 185 ? 55.46147  -34.93775 -8.70927  1.000 47.95463  ? 185 LEU B CB  1 
ATOM   3984 C  CG  . LEU B 1 185 ? 54.17274  -35.75870 -8.68765  1.000 51.13667  ? 185 LEU B CG  1 
ATOM   3985 C  CD1 . LEU B 1 185 ? 53.43323  -35.58016 -9.99946  1.000 51.08922  ? 185 LEU B CD1 1 
ATOM   3986 C  CD2 . LEU B 1 185 ? 54.45269  -37.22061 -8.43268  1.000 55.41355  ? 185 LEU B CD2 1 
ATOM   3987 N  N   . ALA B 1 186 ? 55.69402  -32.38360 -6.62919  1.000 43.79781  ? 186 ALA B N   1 
ATOM   3988 C  CA  . ALA B 1 186 ? 55.31482  -31.80632 -5.34181  1.000 49.25797  ? 186 ALA B CA  1 
ATOM   3989 C  C   . ALA B 1 186 ? 54.36720  -30.62662 -5.52301  1.000 52.34642  ? 186 ALA B C   1 
ATOM   3990 O  O   . ALA B 1 186 ? 53.43341  -30.44471 -4.73307  1.000 48.78255  ? 186 ALA B O   1 
ATOM   3991 C  CB  . ALA B 1 186 ? 56.56031  -31.38073 -4.56475  1.000 42.55241  ? 186 ALA B CB  1 
ATOM   3992 N  N   . GLU B 1 187 ? 54.59606  -29.80972 -6.55422  1.000 49.91976  ? 187 GLU B N   1 
ATOM   3993 C  CA  . GLU B 1 187 ? 53.64899  -28.75014 -6.88662  1.000 53.75640  ? 187 GLU B CA  1 
ATOM   3994 C  C   . GLU B 1 187 ? 52.28257  -29.33174 -7.21964  1.000 57.48528  ? 187 GLU B C   1 
ATOM   3995 O  O   . GLU B 1 187 ? 51.25562  -28.87850 -6.70195  1.000 57.32983  ? 187 GLU B O   1 
ATOM   3996 C  CB  . GLU B 1 187 ? 54.17276  -27.92272 -8.06167  1.000 47.86420  ? 187 GLU B CB  1 
ATOM   3997 C  CG  . GLU B 1 187 ? 55.30933  -26.97968 -7.71885  1.000 51.85061  ? 187 GLU B CG  1 
ATOM   3998 C  CD  . GLU B 1 187 ? 55.69169  -26.09087 -8.88641  1.000 55.07420  ? 187 GLU B CD  1 
ATOM   3999 O  OE1 . GLU B 1 187 ? 56.28475  -26.60123 -9.86102  1.000 53.01570  ? 187 GLU B OE1 1 
ATOM   4000 O  OE2 . GLU B 1 187 ? 55.38528  -24.88238 -8.83513  1.000 54.49831  ? 187 GLU B OE2 1 
ATOM   4001 N  N   . ARG B 1 188 ? 52.25656  -30.34597 -8.08615  1.000 54.95451  ? 188 ARG B N   1 
ATOM   4002 C  CA  . ARG B 1 188 ? 50.99457  -30.95954 -8.48386  1.000 57.60162  ? 188 ARG B CA  1 
ATOM   4003 C  C   . ARG B 1 188 ? 50.31669  -31.64697 -7.30459  1.000 54.76026  ? 188 ARG B C   1 
ATOM   4004 O  O   . ARG B 1 188 ? 49.09036  -31.58005 -7.16019  1.000 59.09200  ? 188 ARG B O   1 
ATOM   4005 C  CB  . ARG B 1 188 ? 51.24412  -31.94469 -9.62866  1.000 52.33838  ? 188 ARG B CB  1 
ATOM   4006 C  CG  . ARG B 1 188 ? 50.18090  -33.01679 -9.80580  1.000 57.26356  ? 188 ARG B CG  1 
ATOM   4007 C  CD  . ARG B 1 188 ? 48.84218  -32.43268 -10.24522 1.000 59.39020  ? 188 ARG B CD  1 
ATOM   4008 N  NE  . ARG B 1 188 ? 47.83657  -33.47664 -10.39808 1.000 56.90128  ? 188 ARG B NE  1 
ATOM   4009 C  CZ  . ARG B 1 188 ? 47.16705  -34.02304 -9.39279  1.000 58.22701  ? 188 ARG B CZ  1 
ATOM   4010 N  NH1 . ARG B 1 188 ? 47.35644  -33.63246 -8.14309  1.000 55.10474  ? 188 ARG B NH1 1 
ATOM   4011 N  NH2 . ARG B 1 188 ? 46.28962  -34.98963 -9.64708  1.000 63.45231  ? 188 ARG B NH2 1 
ATOM   4012 N  N   . ALA B 1 189 ? 51.09857  -32.30332 -6.44376  1.000 51.08854  ? 189 ALA B N   1 
ATOM   4013 C  CA  . ALA B 1 189 ? 50.51480  -33.01641 -5.31213  1.000 55.73709  ? 189 ALA B CA  1 
ATOM   4014 C  C   . ALA B 1 189 ? 49.85511  -32.06501 -4.32166  1.000 59.46610  ? 189 ALA B C   1 
ATOM   4015 O  O   . ALA B 1 189 ? 48.88540  -32.44318 -3.65407  1.000 59.84476  ? 189 ALA B O   1 
ATOM   4016 C  CB  . ALA B 1 189 ? 51.58314  -33.85606 -4.61104  1.000 50.20037  ? 189 ALA B CB  1 
ATOM   4017 N  N   . GLY B 1 190 ? 50.35863  -30.83812 -4.21389  1.000 60.56794  ? 190 GLY B N   1 
ATOM   4018 C  CA  . GLY B 1 190 ? 49.81586  -29.83633 -3.32435  1.000 58.76774  ? 190 GLY B CA  1 
ATOM   4019 C  C   . GLY B 1 190 ? 48.93301  -28.79802 -3.97620  1.000 61.38491  ? 190 GLY B C   1 
ATOM   4020 O  O   . GLY B 1 190 ? 48.48490  -27.87362 -3.29074  1.000 64.12195  ? 190 GLY B O   1 
ATOM   4021 N  N   . ARG B 1 191 ? 48.67971  -28.91476 -5.28206  1.000 61.08516  ? 191 ARG B N   1 
ATOM   4022 C  CA  . ARG B 1 191 ? 47.77300  -28.02257 -6.00905  1.000 65.86428  ? 191 ARG B CA  1 
ATOM   4023 C  C   . ARG B 1 191 ? 48.22288  -26.56327 -5.92106  1.000 68.22103  ? 191 ARG B C   1 
ATOM   4024 O  O   . ARG B 1 191 ? 47.43114  -25.66202 -5.63879  1.000 73.42524  ? 191 ARG B O   1 
ATOM   4025 C  CB  . ARG B 1 191 ? 46.33240  -28.17746 -5.51161  1.000 66.66278  ? 191 ARG B CB  1 
ATOM   4026 C  CG  . ARG B 1 191 ? 45.76642  -29.58464 -5.62671  1.000 63.72801  ? 191 ARG B CG  1 
ATOM   4027 C  CD  . ARG B 1 191 ? 45.50764  -29.97095 -7.07186  1.000 64.91527  ? 191 ARG B CD  1 
ATOM   4028 N  NE  . ARG B 1 191 ? 44.85355  -31.27036 -7.16697  1.000 72.50243  ? 191 ARG B NE  1 
ATOM   4029 C  CZ  . ARG B 1 191 ? 44.60175  -31.90584 -8.30394  1.000 72.60898  ? 191 ARG B CZ  1 
ATOM   4030 N  NH1 . ARG B 1 191 ? 44.93857  -31.39105 -9.47631  1.000 61.99037  ? 191 ARG B NH1 1 
ATOM   4031 N  NH2 . ARG B 1 191 ? 44.00232  -33.09180 -8.26415  1.000 74.71152  ? 191 ARG B NH2 1 
ATOM   4032 N  N   . PHE B 1 192 ? 49.51085  -26.33011 -6.16605  1.000 63.45981  ? 192 PHE B N   1 
ATOM   4033 C  CA  . PHE B 1 192 ? 50.03487  -24.97401 -6.23499  1.000 54.24721  ? 192 PHE B CA  1 
ATOM   4034 C  C   . PHE B 1 192 ? 51.12645  -24.90502 -7.29175  1.000 56.77111  ? 192 PHE B C   1 
ATOM   4035 O  O   . PHE B 1 192 ? 51.67220  -25.92305 -7.72379  1.000 58.18916  ? 192 PHE B O   1 
ATOM   4036 C  CB  . PHE B 1 192 ? 50.57004  -24.48775 -4.87548  1.000 54.64769  ? 192 PHE B CB  1 
ATOM   4037 C  CG  . PHE B 1 192 ? 51.82388  -25.18457 -4.41957  1.000 57.83089  ? 192 PHE B CG  1 
ATOM   4038 C  CD1 . PHE B 1 192 ? 51.75205  -26.35390 -3.68266  1.000 50.56589  ? 192 PHE B CD1 1 
ATOM   4039 C  CD2 . PHE B 1 192 ? 53.07399  -24.65604 -4.70788  1.000 48.59554  ? 192 PHE B CD2 1 
ATOM   4040 C  CE1 . PHE B 1 192 ? 52.90124  -26.99256 -3.25648  1.000 53.08101  ? 192 PHE B CE1 1 
ATOM   4041 C  CE2 . PHE B 1 192 ? 54.22443  -25.29121 -4.28641  1.000 50.07224  ? 192 PHE B CE2 1 
ATOM   4042 C  CZ  . PHE B 1 192 ? 54.13873  -26.45978 -3.55849  1.000 50.06579  ? 192 PHE B CZ  1 
ATOM   4043 N  N   . GLU B 1 193 ? 51.42829  -23.68052 -7.71432  1.000 53.85323  ? 193 GLU B N   1 
ATOM   4044 C  CA  . GLU B 1 193 ? 52.50672  -23.41433 -8.65607  1.000 55.78513  ? 193 GLU B CA  1 
ATOM   4045 C  C   . GLU B 1 193 ? 53.31849  -22.24273 -8.13062  1.000 58.19018  ? 193 GLU B C   1 
ATOM   4046 O  O   . GLU B 1 193 ? 52.77484  -21.15269 -7.92486  1.000 57.81693  ? 193 GLU B O   1 
ATOM   4047 C  CB  . GLU B 1 193 ? 51.96574  -23.11299 -10.05788 1.000 54.21147  ? 193 GLU B CB  1 
ATOM   4048 C  CG  . GLU B 1 193 ? 51.21616  -24.27414 -10.69392 1.000 54.39853  ? 193 GLU B CG  1 
ATOM   4049 C  CD  . GLU B 1 193 ? 50.74310  -23.97071 -12.10163 1.000 58.04332  ? 193 GLU B CD  1 
ATOM   4050 O  OE1 . GLU B 1 193 ? 51.30342  -23.05247 -12.73740 1.000 58.22553  ? 193 GLU B OE1 1 
ATOM   4051 O  OE2 . GLU B 1 193 ? 49.80857  -24.65199 -12.57263 1.000 61.82552  ? 193 GLU B OE2 1 
ATOM   4052 N  N   . VAL B 1 194 ? 54.60521  -22.47534 -7.88797  1.000 53.31939  ? 194 VAL B N   1 
ATOM   4053 C  CA  . VAL B 1 194 ? 55.49389  -21.35745 -7.55821  1.000 54.13511  ? 194 VAL B CA  1 
ATOM   4054 C  C   . VAL B 1 194 ? 55.47520  -20.36550 -8.71557  1.000 52.58026  ? 194 VAL B C   1 
ATOM   4055 O  O   . VAL B 1 194 ? 55.38506  -20.78961 -9.88708  1.000 53.92036  ? 194 VAL B O   1 
ATOM   4056 C  CB  . VAL B 1 194 ? 56.92023  -21.86907 -7.27429  1.000 51.68743  ? 194 VAL B CB  1 
ATOM   4057 C  CG1 . VAL B 1 194 ? 57.52533  -22.53113 -8.50709  1.000 53.20974  ? 194 VAL B CG1 1 
ATOM   4058 C  CG2 . VAL B 1 194 ? 57.82249  -20.75635 -6.76214  1.000 49.52048  ? 194 VAL B CG2 1 
ATOM   4059 N  N   . PRO B 1 195 ? 55.48636  -19.05471 -8.46479  1.000 55.97291  ? 195 PRO B N   1 
ATOM   4060 C  CA  . PRO B 1 195 ? 55.48270  -18.08837 -9.57175  1.000 53.23410  ? 195 PRO B CA  1 
ATOM   4061 C  C   . PRO B 1 195 ? 56.57831  -18.39005 -10.58266 1.000 54.84173  ? 195 PRO B C   1 
ATOM   4062 O  O   . PRO B 1 195 ? 57.73528  -18.62143 -10.22264 1.000 54.04477  ? 195 PRO B O   1 
ATOM   4063 C  CB  . PRO B 1 195 ? 55.71167  -16.75028 -8.86531  1.000 50.84876  ? 195 PRO B CB  1 
ATOM   4064 C  CG  . PRO B 1 195 ? 55.10899  -16.94856 -7.52479  1.000 53.50019  ? 195 PRO B CG  1 
ATOM   4065 C  CD  . PRO B 1 195 ? 55.35192  -18.38779 -7.15717  1.000 54.34707  ? 195 PRO B CD  1 
ATOM   4066 N  N   . HIS B 1 196 ? 56.19685  -18.39508 -11.86338 1.000 50.94781  ? 196 HIS B N   1 
ATOM   4067 C  CA  . HIS B 1 196 ? 57.08484  -18.90528 -12.90330 1.000 54.09691  ? 196 HIS B CA  1 
ATOM   4068 C  C   . HIS B 1 196 ? 58.32748  -18.03842 -13.05779 1.000 57.70935  ? 196 HIS B C   1 
ATOM   4069 O  O   . HIS B 1 196 ? 59.42158  -18.55786 -13.30668 1.000 54.30337  ? 196 HIS B O   1 
ATOM   4070 C  CB  . HIS B 1 196 ? 56.33099  -19.01786 -14.22992 1.000 52.36354  ? 196 HIS B CB  1 
ATOM   4071 C  CG  . HIS B 1 196 ? 55.26489  -20.07034 -14.22965 1.000 50.81683  ? 196 HIS B CG  1 
ATOM   4072 N  ND1 . HIS B 1 196 ? 54.78664  -20.64809 -15.38607 1.000 58.24921  ? 196 HIS B ND1 1 
ATOM   4073 C  CD2 . HIS B 1 196 ? 54.58501  -20.64966 -13.21153 1.000 56.18260  ? 196 HIS B CD2 1 
ATOM   4074 C  CE1 . HIS B 1 196 ? 53.85827  -21.53727 -15.08055 1.000 58.10429  ? 196 HIS B CE1 1 
ATOM   4075 N  NE2 . HIS B 1 196 ? 53.71655  -21.55732 -13.76756 1.000 55.13118  ? 196 HIS B NE2 1 
ATOM   4076 N  N   . ARG B 1 197 ? 58.18814  -16.71899 -12.90974 1.000 52.57497  ? 197 ARG B N   1 
ATOM   4077 C  CA  . ARG B 1 197 ? 59.36010  -15.85751 -13.00310 1.000 51.50194  ? 197 ARG B CA  1 
ATOM   4078 C  C   . ARG B 1 197 ? 60.31598  -16.06378 -11.83517 1.000 51.31770  ? 197 ARG B C   1 
ATOM   4079 O  O   . ARG B 1 197 ? 61.51227  -15.78931 -11.97527 1.000 52.45316  ? 197 ARG B O   1 
ATOM   4080 C  CB  . ARG B 1 197 ? 58.93465  -14.38987 -13.10262 1.000 52.68471  ? 197 ARG B CB  1 
ATOM   4081 C  CG  . ARG B 1 197 ? 58.09570  -13.87146 -11.94423 1.000 56.01967  ? 197 ARG B CG  1 
ATOM   4082 C  CD  . ARG B 1 197 ? 57.40796  -12.56852 -12.33469 1.000 56.97383  ? 197 ARG B CD  1 
ATOM   4083 N  NE  . ARG B 1 197 ? 56.75248  -11.91636 -11.20732 1.000 58.20864  ? 197 ARG B NE  1 
ATOM   4084 C  CZ  . ARG B 1 197 ? 55.52654  -12.19689 -10.78669 1.000 54.84399  ? 197 ARG B CZ  1 
ATOM   4085 N  NH1 . ARG B 1 197 ? 54.79772  -13.14146 -11.35924 1.000 56.80918  ? 197 ARG B NH1 1 
ATOM   4086 N  NH2 . ARG B 1 197 ? 55.01820  -11.51171 -9.76653  1.000 54.21676  ? 197 ARG B NH2 1 
ATOM   4087 N  N   . VAL B 1 198 ? 59.82163  -16.55192 -10.69610 1.000 49.29268  ? 198 VAL B N   1 
ATOM   4088 C  CA  . VAL B 1 198 ? 60.70802  -16.85741 -9.57762  1.000 50.71789  ? 198 VAL B CA  1 
ATOM   4089 C  C   . VAL B 1 198 ? 61.36954  -18.22004 -9.76775  1.000 51.88509  ? 198 VAL B C   1 
ATOM   4090 O  O   . VAL B 1 198 ? 62.53037  -18.40770 -9.38145  1.000 47.78938  ? 198 VAL B O   1 
ATOM   4091 C  CB  . VAL B 1 198 ? 59.94020  -16.77624 -8.24556  1.000 48.03572  ? 198 VAL B CB  1 
ATOM   4092 C  CG1 . VAL B 1 198 ? 60.80580  -17.25543 -7.08620  1.000 43.23327  ? 198 VAL B CG1 1 
ATOM   4093 C  CG2 . VAL B 1 198 ? 59.47970  -15.34981 -7.99345  1.000 50.95333  ? 198 VAL B CG2 1 
ATOM   4094 N  N   . PHE B 1 199 ? 60.66187  -19.18225 -10.36948 1.000 51.19507  ? 199 PHE B N   1 
ATOM   4095 C  CA  . PHE B 1 199 ? 61.28502  -20.46267 -10.69283 1.000 50.43719  ? 199 PHE B CA  1 
ATOM   4096 C  C   . PHE B 1 199 ? 62.52548  -20.26266 -11.55280 1.000 50.89455  ? 199 PHE B C   1 
ATOM   4097 O  O   . PHE B 1 199 ? 63.54513  -20.93273 -11.35302 1.000 50.00750  ? 199 PHE B O   1 
ATOM   4098 C  CB  . PHE B 1 199 ? 60.28316  -21.37885 -11.40184 1.000 46.05396  ? 199 PHE B CB  1 
ATOM   4099 C  CG  . PHE B 1 199 ? 60.84838  -22.72645 -11.77934 1.000 53.74241  ? 199 PHE B CG  1 
ATOM   4100 C  CD1 . PHE B 1 199 ? 61.50846  -22.90890 -12.98806 1.000 52.77253  ? 199 PHE B CD1 1 
ATOM   4101 C  CD2 . PHE B 1 199 ? 60.71264  -23.81274 -10.92957 1.000 47.75240  ? 199 PHE B CD2 1 
ATOM   4102 C  CE1 . PHE B 1 199 ? 62.03010  -24.14303 -13.33152 1.000 51.25683  ? 199 PHE B CE1 1 
ATOM   4103 C  CE2 . PHE B 1 199 ? 61.22867  -25.05033 -11.27341 1.000 45.50233  ? 199 PHE B CE2 1 
ATOM   4104 C  CZ  . PHE B 1 199 ? 61.88789  -25.21399 -12.47297 1.000 42.99117  ? 199 PHE B CZ  1 
ATOM   4105 N  N   . ASP B 1 200 ? 62.46000  -19.33376 -12.50587 1.000 53.49407  ? 200 ASP B N   1 
ATOM   4106 C  CA  . ASP B 1 200 ? 63.57473  -19.04459 -13.39765 1.000 50.64686  ? 200 ASP B CA  1 
ATOM   4107 C  C   . ASP B 1 200 ? 64.60722  -18.10986 -12.78226 1.000 50.25771  ? 200 ASP B C   1 
ATOM   4108 O  O   . ASP B 1 200 ? 65.61935  -17.82422 -13.43140 1.000 50.38128  ? 200 ASP B O   1 
ATOM   4109 C  CB  . ASP B 1 200 ? 63.06144  -18.43228 -14.70410 1.000 54.04199  ? 200 ASP B CB  1 
ATOM   4110 C  CG  . ASP B 1 200 ? 62.10285  -19.34508 -15.44175 1.000 58.86949  ? 200 ASP B CG  1 
ATOM   4111 O  OD1 . ASP B 1 200 ? 62.14979  -20.57258 -15.21626 1.000 63.18343  ? 200 ASP B OD1 1 
ATOM   4112 O  OD2 . ASP B 1 200 ? 61.30505  -18.83328 -16.25300 1.000 64.77801  ? 200 ASP B OD2 1 
ATOM   4113 N  N   . SER B 1 201 ? 64.38110  -17.62067 -11.56636 1.000 44.68574  ? 201 SER B N   1 
ATOM   4114 C  CA  . SER B 1 201 ? 65.31763  -16.68538 -10.96366 1.000 45.23039  ? 201 SER B CA  1 
ATOM   4115 C  C   . SER B 1 201 ? 66.64168  -17.37744 -10.65111 1.000 47.03413  ? 201 SER B C   1 
ATOM   4116 O  O   . SER B 1 201 ? 66.71583  -18.59874 -10.48692 1.000 43.38411  ? 201 SER B O   1 
ATOM   4117 C  CB  . SER B 1 201 ? 64.73017  -16.07640 -9.69079  1.000 50.92342  ? 201 SER B CB  1 
ATOM   4118 O  OG  . SER B 1 201 ? 64.54067  -17.06110 -8.69105  1.000 48.14421  ? 201 SER B OG  1 
ATOM   4119 N  N   . ALA B 1 202 ? 67.70182  -16.57058 -10.57594 1.000 46.35163  ? 202 ALA B N   1 
ATOM   4120 C  CA  . ALA B 1 202 ? 69.02122  -17.11114 -10.26730 1.000 45.66624  ? 202 ALA B CA  1 
ATOM   4121 C  C   . ALA B 1 202 ? 69.04629  -17.75653 -8.88709  1.000 46.16652  ? 202 ALA B C   1 
ATOM   4122 O  O   . ALA B 1 202 ? 69.66010  -18.81404 -8.69988  1.000 43.59845  ? 202 ALA B O   1 
ATOM   4123 C  CB  . ALA B 1 202 ? 70.07410  -16.00766 -10.36314 1.000 42.92779  ? 202 ALA B CB  1 
ATOM   4124 N  N   . VAL B 1 203 ? 68.37820  -17.13855 -7.91027  1.000 43.94592  ? 203 VAL B N   1 
ATOM   4125 C  CA  . VAL B 1 203 ? 68.40861  -17.65021 -6.54239  1.000 36.78620  ? 203 VAL B CA  1 
ATOM   4126 C  C   . VAL B 1 203 ? 67.71301  -19.00388 -6.46016  1.000 40.39700  ? 203 VAL B C   1 
ATOM   4127 O  O   . VAL B 1 203 ? 68.24931  -19.95927 -5.88668  1.000 41.41904  ? 203 VAL B O   1 
ATOM   4128 C  CB  . VAL B 1 203 ? 67.78278  -16.63071 -5.57327  1.000 42.03015  ? 203 VAL B CB  1 
ATOM   4129 C  CG1 . VAL B 1 203 ? 67.51686  -17.27224 -4.21988  1.000 38.47970  ? 203 VAL B CG1 1 
ATOM   4130 C  CG2 . VAL B 1 203 ? 68.69681  -15.42551 -5.41204  1.000 43.15057  ? 203 VAL B CG2 1 
ATOM   4131 N  N   . MET B 1 204 ? 66.51070  -19.10976 -7.03184  1.000 40.25319  ? 204 MET B N   1 
ATOM   4132 C  CA  . MET B 1 204 ? 65.80764  -20.38837 -7.01059  1.000 45.18544  ? 204 MET B CA  1 
ATOM   4133 C  C   . MET B 1 204 ? 66.54893  -21.43410 -7.83365  1.000 43.55727  ? 204 MET B C   1 
ATOM   4134 O  O   . MET B 1 204 ? 66.57168  -22.61503 -7.46916  1.000 45.53667  ? 204 MET B O   1 
ATOM   4135 C  CB  . MET B 1 204 ? 64.37599  -20.21891 -7.51619  1.000 44.69952  ? 204 MET B CB  1 
ATOM   4136 C  CG  . MET B 1 204 ? 63.54509  -21.48913 -7.42707  1.000 39.77950  ? 204 MET B CG  1 
ATOM   4137 S  SD  . MET B 1 204 ? 63.50138  -22.15342 -5.74640  1.000 49.51329  ? 204 MET B SD  1 
ATOM   4138 C  CE  . MET B 1 204 ? 62.57971  -20.87046 -4.90617  1.000 47.37114  ? 204 MET B CE  1 
ATOM   4139 N  N   . SER B 1 205 ? 67.15688  -21.02037 -8.94863  1.000 41.99806  ? 205 SER B N   1 
ATOM   4140 C  CA  A SER B 1 205 ? 67.95864  -21.95155 -9.73480  0.528 42.81704  ? 205 SER B CA  1 
ATOM   4141 C  CA  B SER B 1 205 ? 67.96361  -21.94479 -9.73807  0.472 42.94632  ? 205 SER B CA  1 
ATOM   4142 C  C   . SER B 1 205 ? 69.09070  -22.53620 -8.89993  1.000 45.67598  ? 205 SER B C   1 
ATOM   4143 O  O   . SER B 1 205 ? 69.40513  -23.72649 -9.01665  1.000 41.39178  ? 205 SER B O   1 
ATOM   4144 C  CB  A SER B 1 205 ? 68.50979  -21.25568 -10.98076 0.528 41.96814  ? 205 SER B CB  1 
ATOM   4145 C  CB  B SER B 1 205 ? 68.52111  -21.22791 -10.97007 0.472 42.17377  ? 205 SER B CB  1 
ATOM   4146 O  OG  A SER B 1 205 ? 67.47284  -20.95271 -11.89787 0.528 43.46943  ? 205 SER B OG  1 
ATOM   4147 O  OG  B SER B 1 205 ? 69.28395  -22.10355 -11.78089 0.472 43.20590  ? 205 SER B OG  1 
ATOM   4148 N  N   . ALA B 1 206 ? 69.70517  -21.71629 -8.04073  1.000 40.10017  ? 206 ALA B N   1 
ATOM   4149 C  CA  . ALA B 1 206 ? 70.77095  -22.21045 -7.17606  1.000 36.97846  ? 206 ALA B CA  1 
ATOM   4150 C  C   . ALA B 1 206 ? 70.22157  -23.12671 -6.08869  1.000 41.88579  ? 206 ALA B C   1 
ATOM   4151 O  O   . ALA B 1 206 ? 70.85824  -24.12610 -5.73333  1.000 39.92749  ? 206 ALA B O   1 
ATOM   4152 C  CB  . ALA B 1 206 ? 71.53294  -21.03746 -6.56225  1.000 37.37321  ? 206 ALA B CB  1 
ATOM   4153 N  N   . MET B 1 207 ? 69.04134  -22.80499 -5.55083  1.000 38.11224  ? 207 MET B N   1 
ATOM   4154 C  CA  . MET B 1 207 ? 68.41153  -23.67497 -4.56102  1.000 40.80433  ? 207 MET B CA  1 
ATOM   4155 C  C   . MET B 1 207 ? 68.08893  -25.04201 -5.15419  1.000 39.33836  ? 207 MET B C   1 
ATOM   4156 O  O   . MET B 1 207 ? 68.33137  -26.07877 -4.52366  1.000 41.39163  ? 207 MET B O   1 
ATOM   4157 C  CB  . MET B 1 207 ? 67.14719  -23.01344 -4.00932  1.000 41.37996  ? 207 MET B CB  1 
ATOM   4158 C  CG  . MET B 1 207 ? 67.41358  -21.86947 -3.04027  1.000 40.25816  ? 207 MET B CG  1 
ATOM   4159 S  SD  . MET B 1 207 ? 65.93649  -20.89895 -2.66822  1.000 46.67129  ? 207 MET B SD  1 
ATOM   4160 C  CE  . MET B 1 207 ? 64.83024  -22.16833 -2.05888  1.000 44.83151  ? 207 MET B CE  1 
ATOM   4161 N  N   . LEU B 1 208 ? 67.53436  -25.06286 -6.36958  1.000 41.07272  ? 208 LEU B N   1 
ATOM   4162 C  CA  . LEU B 1 208 ? 67.21777  -26.33356 -7.01572  1.000 41.51038  ? 208 LEU B CA  1 
ATOM   4163 C  C   . LEU B 1 208 ? 68.48375  -27.10183 -7.38330  1.000 39.80400  ? 208 LEU B C   1 
ATOM   4164 O  O   . LEU B 1 208 ? 68.51581  -28.33430 -7.28958  1.000 37.97675  ? 208 LEU B O   1 
ATOM   4165 C  CB  . LEU B 1 208 ? 66.35008  -26.09275 -8.25028  1.000 38.46094  ? 208 LEU B CB  1 
ATOM   4166 C  CG  . LEU B 1 208 ? 64.90702  -25.64955 -7.98878  1.000 47.68606  ? 208 LEU B CG  1 
ATOM   4167 C  CD1 . LEU B 1 208 ? 64.24067  -25.22009 -9.28126  1.000 42.48118  ? 208 LEU B CD1 1 
ATOM   4168 C  CD2 . LEU B 1 208 ? 64.10752  -26.76235 -7.32555  1.000 33.97808  ? 208 LEU B CD2 1 
ATOM   4169 N  N   . GLN B 1 209 ? 69.53855  -26.39619 -7.79906  1.000 35.74101  ? 209 GLN B N   1 
ATOM   4170 C  CA  . GLN B 1 209 ? 70.79921  -27.07340 -8.08653  1.000 37.44745  ? 209 GLN B CA  1 
ATOM   4171 C  C   . GLN B 1 209 ? 71.36412  -27.74471 -6.83983  1.000 46.42383  ? 209 GLN B C   1 
ATOM   4172 O  O   . GLN B 1 209 ? 71.96572  -28.82292 -6.92968  1.000 39.51686  ? 209 GLN B O   1 
ATOM   4173 C  CB  . GLN B 1 209 ? 71.81311  -26.08347 -8.66193  1.000 38.17548  ? 209 GLN B CB  1 
ATOM   4174 C  CG  . GLN B 1 209 ? 73.12673  -26.72850 -9.08287  1.000 44.36814  ? 209 GLN B CG  1 
ATOM   4175 C  CD  . GLN B 1 209 ? 74.24909  -25.72515 -9.27575  1.000 49.86879  ? 209 GLN B CD  1 
ATOM   4176 O  OE1 . GLN B 1 209 ? 74.88942  -25.29737 -8.31175  1.000 46.88360  ? 209 GLN B OE1 1 
ATOM   4177 N  NE2 . GLN B 1 209 ? 74.50383  -25.35583 -10.52672 1.000 48.80089  ? 209 GLN B NE2 1 
ATOM   4178 N  N   . ILE B 1 210 ? 71.17210  -27.12867 -5.67129  1.000 38.10674  ? 210 ILE B N   1 
ATOM   4179 C  CA  . ILE B 1 210 ? 71.60627  -27.74388 -4.42287  1.000 38.77145  ? 210 ILE B CA  1 
ATOM   4180 C  C   . ILE B 1 210 ? 70.79196  -28.99775 -4.13434  1.000 39.55283  ? 210 ILE B C   1 
ATOM   4181 O  O   . ILE B 1 210 ? 71.34455  -30.03850 -3.75948  1.000 37.76296  ? 210 ILE B O   1 
ATOM   4182 C  CB  . ILE B 1 210 ? 71.51085  -26.72612 -3.27184  1.000 43.51539  ? 210 ILE B CB  1 
ATOM   4183 C  CG1 . ILE B 1 210 ? 72.63621  -25.69498 -3.37603  1.000 38.90304  ? 210 ILE B CG1 1 
ATOM   4184 C  CG2 . ILE B 1 210 ? 71.53145  -27.43346 -1.91780  1.000 45.39433  ? 210 ILE B CG2 1 
ATOM   4185 C  CD1 . ILE B 1 210 ? 72.54183  -24.58868 -2.34832  1.000 41.18512  ? 210 ILE B CD1 1 
ATOM   4186 N  N   . ALA B 1 211 ? 69.46852  -28.92034 -4.30445  1.000 41.31938  ? 211 ALA B N   1 
ATOM   4187 C  CA  . ALA B 1 211 ? 68.61957  -30.08670 -4.08250  1.000 40.95822  ? 211 ALA B CA  1 
ATOM   4188 C  C   . ALA B 1 211 ? 69.01869  -31.24078 -4.99320  1.000 37.79874  ? 211 ALA B C   1 
ATOM   4189 O  O   . ALA B 1 211 ? 69.07249  -32.39603 -4.55694  1.000 38.51679  ? 211 ALA B O   1 
ATOM   4190 C  CB  . ALA B 1 211 ? 67.15263  -29.71585 -4.29835  1.000 37.87891  ? 211 ALA B CB  1 
ATOM   4191 N  N   . VAL B 1 212 ? 69.31344  -30.94445 -6.25990  1.000 38.14698  ? 212 VAL B N   1 
ATOM   4192 C  CA  . VAL B 1 212 ? 69.75219  -31.98173 -7.18963  1.000 36.64319  ? 212 VAL B CA  1 
ATOM   4193 C  C   . VAL B 1 212 ? 71.09063  -32.56388 -6.74524  1.000 40.67457  ? 212 VAL B C   1 
ATOM   4194 O  O   . VAL B 1 212 ? 71.27382  -33.78593 -6.70543  1.000 41.38085  ? 212 VAL B O   1 
ATOM   4195 C  CB  . VAL B 1 212 ? 69.82801  -31.41840 -8.62039  1.000 38.63608  ? 212 VAL B CB  1 
ATOM   4196 C  CG1 . VAL B 1 212 ? 70.42269  -32.44758 -9.56142  1.000 39.18468  ? 212 VAL B CG1 1 
ATOM   4197 C  CG2 . VAL B 1 212 ? 68.44764  -30.98685 -9.09880  1.000 34.97488  ? 212 VAL B CG2 1 
ATOM   4198 N  N   . ASP B 1 213 ? 72.04256  -31.69523 -6.39406  1.000 39.40724  ? 213 ASP B N   1 
ATOM   4199 C  CA  . ASP B 1 213 ? 73.39051  -32.15266 -6.06470  1.000 42.74685  ? 213 ASP B CA  1 
ATOM   4200 C  C   . ASP B 1 213 ? 73.40119  -33.00271 -4.79978  1.000 42.99636  ? 213 ASP B C   1 
ATOM   4201 O  O   . ASP B 1 213 ? 74.02652  -34.06750 -4.76509  1.000 44.82143  ? 213 ASP B O   1 
ATOM   4202 C  CB  . ASP B 1 213 ? 74.33061  -30.95514 -5.91732  1.000 43.23297  ? 213 ASP B CB  1 
ATOM   4203 C  CG  . ASP B 1 213 ? 74.68723  -30.32804 -7.25360  1.000 52.03570  ? 213 ASP B CG  1 
ATOM   4204 O  OD1 . ASP B 1 213 ? 74.22899  -30.84446 -8.29805  1.000 50.74639  ? 213 ASP B OD1 1 
ATOM   4205 O  OD2 . ASP B 1 213 ? 75.42854  -29.32228 -7.26239  1.000 50.26772  ? 213 ASP B OD2 1 
ATOM   4206 N  N   . VAL B 1 214 ? 72.71960  -32.54706 -3.74720  1.000 40.42200  ? 214 VAL B N   1 
ATOM   4207 C  CA  . VAL B 1 214 ? 72.68135  -33.31001 -2.50172  1.000 41.25044  ? 214 VAL B CA  1 
ATOM   4208 C  C   . VAL B 1 214 ? 72.09063  -34.69401 -2.74039  1.000 43.24028  ? 214 VAL B C   1 
ATOM   4209 O  O   . VAL B 1 214 ? 72.57122  -35.69393 -2.19339  1.000 39.99009  ? 214 VAL B O   1 
ATOM   4210 C  CB  . VAL B 1 214 ? 71.89904  -32.53388 -1.42583  1.000 41.51244  ? 214 VAL B CB  1 
ATOM   4211 C  CG1 . VAL B 1 214 ? 71.66460  -33.40879 -0.19536  1.000 42.94698  ? 214 VAL B CG1 1 
ATOM   4212 C  CG2 . VAL B 1 214 ? 72.64524  -31.25974 -1.05587  1.000 37.10624  ? 214 VAL B CG2 1 
ATOM   4213 N  N   . ASN B 1 215 ? 71.04962  -34.77444 -3.57197  1.000 41.39790  ? 215 ASN B N   1 
ATOM   4214 C  CA  . ASN B 1 215 ? 70.41288  -36.05732 -3.85031  1.000 41.75397  ? 215 ASN B CA  1 
ATOM   4215 C  C   . ASN B 1 215 ? 71.35948  -37.01219 -4.56908  1.000 40.88678  ? 215 ASN B C   1 
ATOM   4216 O  O   . ASN B 1 215 ? 71.40288  -38.20726 -4.25564  1.000 37.93061  ? 215 ASN B O   1 
ATOM   4217 C  CB  . ASN B 1 215 ? 69.15267  -35.84119 -4.68319  1.000 41.60775  ? 215 ASN B CB  1 
ATOM   4218 C  CG  . ASN B 1 215 ? 67.90078  -35.73817 -3.83970  1.000 42.63506  ? 215 ASN B CG  1 
ATOM   4219 O  OD1 . ASN B 1 215 ? 67.21851  -36.73340 -3.60868  1.000 47.36432  ? 215 ASN B OD1 1 
ATOM   4220 N  ND2 . ASN B 1 215 ? 67.58124  -34.52962 -3.39006  1.000 40.54602  ? 215 ASN B ND2 1 
ATOM   4221 N  N   . LEU B 1 216 ? 72.11483  -36.51321 -5.54760  1.000 39.98068  ? 216 LEU B N   1 
ATOM   4222 C  CA  . LEU B 1 216 ? 72.99556  -37.40374 -6.29433  1.000 47.24034  ? 216 LEU B CA  1 
ATOM   4223 C  C   . LEU B 1 216 ? 74.23039  -37.78692 -5.49023  1.000 38.89735  ? 216 LEU B C   1 
ATOM   4224 O  O   . LEU B 1 216 ? 74.74864  -38.89593 -5.65743  1.000 45.14870  ? 216 LEU B O   1 
ATOM   4225 C  CB  . LEU B 1 216 ? 73.38817  -36.77134 -7.63613  1.000 44.59200  ? 216 LEU B CB  1 
ATOM   4226 C  CG  . LEU B 1 216 ? 74.32440  -35.56412 -7.73634  1.000 50.02328  ? 216 LEU B CG  1 
ATOM   4227 C  CD1 . LEU B 1 216 ? 75.79121  -35.99341 -7.77911  1.000 47.55395  ? 216 LEU B CD1 1 
ATOM   4228 C  CD2 . LEU B 1 216 ? 73.96588  -34.73255 -8.96800  1.000 45.19083  ? 216 LEU B CD2 1 
ATOM   4229 N  N   . LEU B 1 217 ? 74.71385  -36.89687 -4.62071  1.000 40.96747  ? 217 LEU B N   1 
ATOM   4230 C  CA  . LEU B 1 217 ? 75.82375  -37.25396 -3.74215  1.000 44.37853  ? 217 LEU B CA  1 
ATOM   4231 C  C   . LEU B 1 217 ? 75.40730  -38.34551 -2.76419  1.000 46.64403  ? 217 LEU B C   1 
ATOM   4232 O  O   . LEU B 1 217 ? 76.13402  -39.32507 -2.55890  1.000 42.34359  ? 217 LEU B O   1 
ATOM   4233 C  CB  . LEU B 1 217 ? 76.32252  -36.01775 -2.98956  1.000 41.31069  ? 217 LEU B CB  1 
ATOM   4234 C  CG  . LEU B 1 217 ? 76.95410  -34.90733 -3.83223  1.000 47.08923  ? 217 LEU B CG  1 
ATOM   4235 C  CD1 . LEU B 1 217 ? 77.32265  -33.71512 -2.96399  1.000 44.75196  ? 217 LEU B CD1 1 
ATOM   4236 C  CD2 . LEU B 1 217 ? 78.17150  -35.42351 -4.57316  1.000 44.95708  ? 217 LEU B CD2 1 
ATOM   4237 N  N   . LEU B 1 218 ? 74.23119  -38.18848 -2.15008  1.000 45.02138  ? 218 LEU B N   1 
ATOM   4238 C  CA  . LEU B 1 218 ? 73.71669  -39.21127 -1.24466  1.000 45.19755  ? 218 LEU B CA  1 
ATOM   4239 C  C   . LEU B 1 218 ? 73.51222  -40.53489 -1.96927  1.000 43.69153  ? 218 LEU B C   1 
ATOM   4240 O  O   . LEU B 1 218 ? 73.83301  -41.60102 -1.43258  1.000 42.72956  ? 218 LEU B O   1 
ATOM   4241 C  CB  . LEU B 1 218 ? 72.40382  -38.74107 -0.61526  1.000 39.79937  ? 218 LEU B CB  1 
ATOM   4242 C  CG  . LEU B 1 218 ? 72.42200  -37.99472 0.72242   1.000 48.90058  ? 218 LEU B CG  1 
ATOM   4243 C  CD1 . LEU B 1 218 ? 73.59525  -37.03972 0.82096   1.000 55.84026  ? 218 LEU B CD1 1 
ATOM   4244 C  CD2 . LEU B 1 218 ? 71.11469  -37.23985 0.90403   1.000 50.24026  ? 218 LEU B CD2 1 
ATOM   4245 N  N   . ASN B 1 219 ? 72.98418  -40.48639 -3.19464  1.000 40.76317  ? 219 ASN B N   1 
ATOM   4246 C  CA  . ASN B 1 219 ? 72.71244  -41.71779 -3.92908  1.000 43.26505  ? 219 ASN B CA  1 
ATOM   4247 C  C   . ASN B 1 219 ? 74.00155  -42.39635 -4.38084  1.000 47.82735  ? 219 ASN B C   1 
ATOM   4248 O  O   . ASN B 1 219 ? 74.08305  -43.62983 -4.40204  1.000 47.11734  ? 219 ASN B O   1 
ATOM   4249 C  CB  . ASN B 1 219 ? 71.80989  -41.42912 -5.12869  1.000 46.67258  ? 219 ASN B CB  1 
ATOM   4250 C  CG  . ASN B 1 219 ? 71.47956  -42.67993 -5.91878  1.000 53.53488  ? 219 ASN B CG  1 
ATOM   4251 O  OD1 . ASN B 1 219 ? 72.01740  -42.90408 -7.00168  1.000 60.32273  ? 219 ASN B OD1 1 
ATOM   4252 N  ND2 . ASN B 1 219 ? 70.60254  -43.51232 -5.36901  1.000 52.91389  ? 219 ASN B ND2 1 
ATOM   4253 N  N   . ASP B 1 220 ? 75.02003  -41.61312 -4.74742  1.000 42.59591  ? 220 ASP B N   1 
ATOM   4254 C  CA  . ASP B 1 220 ? 76.28119  -42.21088 -5.17473  1.000 42.13152  ? 220 ASP B CA  1 
ATOM   4255 C  C   . ASP B 1 220 ? 76.98971  -42.92549 -4.02872  1.000 46.98220  ? 220 ASP B C   1 
ATOM   4256 O  O   . ASP B 1 220 ? 77.66704  -43.93402 -4.25544  1.000 43.92136  ? 220 ASP B O   1 
ATOM   4257 C  CB  . ASP B 1 220 ? 77.18644  -41.14529 -5.79012  1.000 37.96166  ? 220 ASP B CB  1 
ATOM   4258 C  CG  . ASP B 1 220 ? 76.95308  -40.97680 -7.28364  1.000 43.71222  ? 220 ASP B CG  1 
ATOM   4259 O  OD1 . ASP B 1 220 ? 75.96152  -41.53417 -7.80172  1.000 46.00761  ? 220 ASP B OD1 1 
ATOM   4260 O  OD2 . ASP B 1 220 ? 77.76904  -40.29938 -7.94068  1.000 47.70495  ? 220 ASP B OD2 1 
ATOM   4261 N  N   . ILE B 1 221 ? 76.84569  -42.43094 -2.79863  1.000 41.15232  ? 221 ILE B N   1 
ATOM   4262 C  CA  . ILE B 1 221 ? 77.41677  -43.13577 -1.65588  1.000 48.17464  ? 221 ILE B CA  1 
ATOM   4263 C  C   . ILE B 1 221 ? 76.59134  -44.37476 -1.32612  1.000 50.57887  ? 221 ILE B C   1 
ATOM   4264 O  O   . ILE B 1 221 ? 77.13927  -45.43642 -1.00718  1.000 44.61014  ? 221 ILE B O   1 
ATOM   4265 C  CB  . ILE B 1 221 ? 77.53940  -42.18199 -0.45380  1.000 48.18039  ? 221 ILE B CB  1 
ATOM   4266 C  CG1 . ILE B 1 221 ? 78.79880  -41.32413 -0.60028  1.000 45.67720  ? 221 ILE B CG1 1 
ATOM   4267 C  CG2 . ILE B 1 221 ? 77.56542  -42.95646 0.85207   1.000 49.85375  ? 221 ILE B CG2 1 
ATOM   4268 C  CD1 . ILE B 1 221 ? 78.85917  -40.15486 0.34173   1.000 48.00076  ? 221 ILE B CD1 1 
ATOM   4269 N  N   . ALA B 1 222 ? 75.26483  -44.27061 -1.42463  1.000 50.21526  ? 222 ALA B N   1 
ATOM   4270 C  CA  . ALA B 1 222 ? 74.41090  -45.41774 -1.13694  1.000 50.88096  ? 222 ALA B CA  1 
ATOM   4271 C  C   . ALA B 1 222 ? 74.59690  -46.53757 -2.15405  1.000 57.10424  ? 222 ALA B C   1 
ATOM   4272 O  O   . ALA B 1 222 ? 74.41012  -47.71247 -1.81770  1.000 55.85811  ? 222 ALA B O   1 
ATOM   4273 C  CB  . ALA B 1 222 ? 72.94738  -44.98217 -1.09245  1.000 47.12663  ? 222 ALA B CB  1 
ATOM   4274 N  N   . SER B 1 223 ? 74.95881  -46.20207 -3.39055  1.000 49.02503  ? 223 SER B N   1 
ATOM   4275 C  CA  . SER B 1 223 ? 75.15674  -47.18936 -4.44419  1.000 52.77935  ? 223 SER B CA  1 
ATOM   4276 C  C   . SER B 1 223 ? 76.60700  -47.63428 -4.57431  1.000 46.80011  ? 223 SER B C   1 
ATOM   4277 O  O   . SER B 1 223 ? 76.92748  -48.37656 -5.50791  1.000 51.30134  ? 223 SER B O   1 
ATOM   4278 C  CB  . SER B 1 223 ? 74.67832  -46.62928 -5.79098  1.000 43.01807  ? 223 SER B CB  1 
ATOM   4279 O  OG  . SER B 1 223 ? 73.38823  -46.05470 -5.68269  1.000 57.03430  ? 223 SER B OG  1 
ATOM   4280 N  N   . LEU B 1 224 ? 77.48009  -47.20965 -3.65790  1.000 47.59949  ? 224 LEU B N   1 
ATOM   4281 C  CA  . LEU B 1 224 ? 78.91771  -47.38789 -3.84625  1.000 50.25740  ? 224 LEU B CA  1 
ATOM   4282 C  C   . LEU B 1 224 ? 79.29882  -48.86366 -3.93674  1.000 54.32412  ? 224 LEU B C   1 
ATOM   4283 O  O   . LEU B 1 224 ? 80.02893  -49.26885 -4.84910  1.000 51.91781  ? 224 LEU B O   1 
ATOM   4284 C  CB  . LEU B 1 224 ? 79.67805  -46.69663 -2.71304  1.000 49.65832  ? 224 LEU B CB  1 
ATOM   4285 C  CG  . LEU B 1 224 ? 81.20533  -46.70845 -2.79220  1.000 49.22421  ? 224 LEU B CG  1 
ATOM   4286 C  CD1 . LEU B 1 224 ? 81.67611  -46.12203 -4.11124  1.000 47.23543  ? 224 LEU B CD1 1 
ATOM   4287 C  CD2 . LEU B 1 224 ? 81.80349  -45.94362 -1.62088  1.000 46.31021  ? 224 LEU B CD2 1 
ATOM   4288 N  N   . GLU B 1 225 ? 78.81332  -49.68470 -3.00029  1.000 52.04270  ? 225 GLU B N   1 
ATOM   4289 C  CA  . GLU B 1 225 ? 79.17664  -51.10066 -2.99802  1.000 52.14583  ? 225 GLU B CA  1 
ATOM   4290 C  C   . GLU B 1 225 ? 78.80548  -51.77067 -4.31458  1.000 52.52920  ? 225 GLU B C   1 
ATOM   4291 O  O   . GLU B 1 225 ? 79.61467  -52.49434 -4.90715  1.000 55.31363  ? 225 GLU B O   1 
ATOM   4292 C  CB  . GLU B 1 225 ? 78.50557  -51.82174 -1.83012  1.000 55.47669  ? 225 GLU B CB  1 
ATOM   4293 C  CG  . GLU B 1 225 ? 78.69785  -53.33309 -1.87059  1.000 64.94937  ? 225 GLU B CG  1 
ATOM   4294 C  CD  . GLU B 1 225 ? 78.03081  -54.04980 -0.71082  1.000 71.16294  ? 225 GLU B CD  1 
ATOM   4295 O  OE1 . GLU B 1 225 ? 77.66599  -53.38134 0.28061   1.000 76.32306  ? 225 GLU B OE1 1 
ATOM   4296 O  OE2 . GLU B 1 225 ? 77.87106  -55.28647 -0.79217  1.000 60.81304  ? 225 GLU B OE2 1 
ATOM   4297 N  N   . LYS B 1 226 ? 77.58265  -51.53357 -4.79121  1.000 52.95511  ? 226 LYS B N   1 
ATOM   4298 C  CA  . LYS B 1 226 ? 77.13643  -52.15902 -6.03129  1.000 51.36771  ? 226 LYS B CA  1 
ATOM   4299 C  C   . LYS B 1 226 ? 77.94664  -51.67099 -7.22716  1.000 54.22937  ? 226 LYS B C   1 
ATOM   4300 O  O   . LYS B 1 226 ? 78.34694  -52.46868 -8.08339  1.000 56.62348  ? 226 LYS B O   1 
ATOM   4301 C  CB  . LYS B 1 226 ? 75.64791  -51.88420 -6.24220  1.000 49.85817  ? 226 LYS B CB  1 
ATOM   4302 C  CG  . LYS B 1 226 ? 75.12863  -52.29168 -7.60715  1.000 52.83339  ? 226 LYS B CG  1 
ATOM   4303 N  N   . GLU B 1 227 ? 78.20811  -50.36547 -7.30085  1.000 52.64258  ? 227 GLU B N   1 
ATOM   4304 C  CA  . GLU B 1 227 ? 78.85539  -49.81427 -8.48603  1.000 54.40109  ? 227 GLU B CA  1 
ATOM   4305 C  C   . GLU B 1 227 ? 80.36644  -50.01523 -8.46872  1.000 47.96931  ? 227 GLU B C   1 
ATOM   4306 O  O   . GLU B 1 227 ? 80.98844  -50.08277 -9.53522  1.000 50.99401  ? 227 GLU B O   1 
ATOM   4307 C  CB  . GLU B 1 227 ? 78.49575  -48.33413 -8.62974  1.000 55.76290  ? 227 GLU B CB  1 
ATOM   4308 C  CG  . GLU B 1 227 ? 76.99861  -48.11451 -8.82969  1.000 56.88300  ? 227 GLU B CG  1 
ATOM   4309 C  CD  . GLU B 1 227 ? 76.64906  -46.70385 -9.26378  1.000 62.87950  ? 227 GLU B CD  1 
ATOM   4310 O  OE1 . GLU B 1 227 ? 77.40461  -45.76810 -8.92781  1.000 60.86659  ? 227 GLU B OE1 1 
ATOM   4311 O  OE2 . GLU B 1 227 ? 75.61636  -46.53270 -9.94667  1.000 64.98645  ? 227 GLU B OE2 1 
ATOM   4312 N  N   . GLU B 1 228 ? 80.97304  -50.12035 -7.28549  1.000 47.45413  ? 228 GLU B N   1 
ATOM   4313 C  CA  . GLU B 1 228 ? 82.38224  -50.49216 -7.22175  1.000 51.84055  ? 228 GLU B CA  1 
ATOM   4314 C  C   . GLU B 1 228 ? 82.57870  -51.95320 -7.60600  1.000 57.43621  ? 228 GLU B C   1 
ATOM   4315 O  O   . GLU B 1 228 ? 83.56268  -52.30151 -8.26850  1.000 60.30936  ? 228 GLU B O   1 
ATOM   4316 C  CB  . GLU B 1 228 ? 82.93488  -50.22702 -5.82202  1.000 51.84612  ? 228 GLU B CB  1 
ATOM   4317 C  CG  . GLU B 1 228 ? 84.33180  -50.78197 -5.58566  1.000 59.77929  ? 228 GLU B CG  1 
ATOM   4318 C  CD  . GLU B 1 228 ? 84.77098  -50.66085 -4.13663  1.000 76.34281  ? 228 GLU B CD  1 
ATOM   4319 O  OE1 . GLU B 1 228 ? 84.25721  -49.76723 -3.42998  1.000 72.45080  ? 228 GLU B OE1 1 
ATOM   4320 O  OE2 . GLU B 1 228 ? 85.62489  -51.46457 -3.70216  1.000 79.40301  ? 228 GLU B OE2 1 
ATOM   4321 N  N   . ALA B 1 229 ? 81.64302  -52.81916 -7.20968  1.000 59.37587  ? 229 ALA B N   1 
ATOM   4322 C  CA  . ALA B 1 229 ? 81.76889  -54.24257 -7.50166  1.000 56.00976  ? 229 ALA B CA  1 
ATOM   4323 C  C   . ALA B 1 229 ? 81.63979  -54.53250 -8.98961  1.000 53.71889  ? 229 ALA B C   1 
ATOM   4324 O  O   . ALA B 1 229 ? 82.25885  -55.47869 -9.48894  1.000 58.37262  ? 229 ALA B O   1 
ATOM   4325 C  CB  . ALA B 1 229 ? 80.71977  -55.03308 -6.72103  1.000 55.90583  ? 229 ALA B CB  1 
ATOM   4326 N  N   . ARG B 1 230 ? 80.84550  -53.74358 -9.70985  1.000 54.36924  ? 230 ARG B N   1 
ATOM   4327 C  CA  . ARG B 1 230 ? 80.62274  -53.95278 -11.13321 1.000 55.08525  ? 230 ARG B CA  1 
ATOM   4328 C  C   . ARG B 1 230 ? 81.51637  -53.08121 -12.00719 1.000 58.68885  ? 230 ARG B C   1 
ATOM   4329 O  O   . ARG B 1 230 ? 81.31489  -53.03022 -13.22486 1.000 58.39038  ? 230 ARG B O   1 
ATOM   4330 C  CB  . ARG B 1 230 ? 79.15356  -53.70679 -11.47741 1.000 58.23537  ? 230 ARG B CB  1 
ATOM   4331 C  CG  . ARG B 1 230 ? 78.19331  -54.59626 -10.70699 1.000 62.95734  ? 230 ARG B CG  1 
ATOM   4332 C  CD  . ARG B 1 230 ? 76.90172  -54.81211 -11.47903 1.000 62.12340  ? 230 ARG B CD  1 
ATOM   4333 N  NE  . ARG B 1 230 ? 76.03306  -55.78062 -10.82112 1.000 67.81547  ? 230 ARG B NE  1 
ATOM   4334 C  CZ  . ARG B 1 230 ? 74.91527  -55.47222 -10.17849 1.000 68.58737  ? 230 ARG B CZ  1 
ATOM   4335 N  NH1 . ARG B 1 230 ? 74.47785  -54.22596 -10.11156 1.000 74.68854  ? 230 ARG B NH1 1 
ATOM   4336 N  NH2 . ARG B 1 230 ? 74.21541  -56.43989 -9.59330  1.000 69.01567  ? 230 ARG B NH2 1 
ATOM   4337 N  N   . GLY B 1 231 ? 82.49522  -52.39862 -11.41932 1.000 58.85790  ? 231 GLY B N   1 
ATOM   4338 C  CA  . GLY B 1 231 ? 83.41526  -51.59715 -12.20310 1.000 56.85657  ? 231 GLY B CA  1 
ATOM   4339 C  C   . GLY B 1 231 ? 82.81664  -50.34921 -12.81088 1.000 56.15804  ? 231 GLY B C   1 
ATOM   4340 O  O   . GLY B 1 231 ? 83.29254  -49.88862 -13.85355 1.000 57.66830  ? 231 GLY B O   1 
ATOM   4341 N  N   . GLU B 1 232 ? 81.77639  -49.79170 -12.19679 1.000 58.85901  ? 232 GLU B N   1 
ATOM   4342 C  CA  . GLU B 1 232 ? 81.24088  -48.52044 -12.66232 1.000 60.23827  ? 232 GLU B CA  1 
ATOM   4343 C  C   . GLU B 1 232 ? 82.23187  -47.40623 -12.35647 1.000 56.90678  ? 232 GLU B C   1 
ATOM   4344 O  O   . GLU B 1 232 ? 82.72054  -47.28612 -11.22886 1.000 53.45091  ? 232 GLU B O   1 
ATOM   4345 C  CB  . GLU B 1 232 ? 79.89435  -48.22479 -12.00532 1.000 58.05036  ? 232 GLU B CB  1 
ATOM   4346 C  CG  . GLU B 1 232 ? 79.34396  -46.84272 -12.33606 1.000 55.60792  ? 232 GLU B CG  1 
ATOM   4347 C  CD  . GLU B 1 232 ? 79.05227  -46.66563 -13.81611 1.000 63.35147  ? 232 GLU B CD  1 
ATOM   4348 O  OE1 . GLU B 1 232 ? 78.16698  -47.37550 -14.33799 1.000 76.24671  ? 232 GLU B OE1 1 
ATOM   4349 O  OE2 . GLU B 1 232 ? 79.71203  -45.82215 -14.46183 1.000 64.42339  ? 232 GLU B OE2 1 
ATOM   4350 N  N   . GLN B 1 233 ? 82.54232  -46.60009 -13.36885 1.000 52.61312  ? 233 GLN B N   1 
ATOM   4351 C  CA  . GLN B 1 233 ? 83.47186  -45.49368 -13.20269 1.000 48.76702  ? 233 GLN B CA  1 
ATOM   4352 C  C   . GLN B 1 233 ? 82.77823  -44.16332 -12.95835 1.000 47.07805  ? 233 GLN B C   1 
ATOM   4353 O  O   . GLN B 1 233 ? 83.38551  -43.26830 -12.36091 1.000 48.36726  ? 233 GLN B O   1 
ATOM   4354 C  CB  . GLN B 1 233 ? 84.37802  -45.37595 -14.43483 1.000 57.18502  ? 233 GLN B CB  1 
ATOM   4355 C  CG  . GLN B 1 233 ? 85.33205  -46.55047 -14.60466 1.000 60.88383  ? 233 GLN B CG  1 
ATOM   4356 C  CD  . GLN B 1 233 ? 85.82372  -46.71179 -16.03103 1.000 77.37384  ? 233 GLN B CD  1 
ATOM   4357 O  OE1 . GLN B 1 233 ? 85.32619  -46.06395 -16.95213 1.000 76.03597  ? 233 GLN B OE1 1 
ATOM   4358 N  NE2 . GLN B 1 233 ? 86.80293  -47.58743 -16.22074 1.000 87.00388  ? 233 GLN B NE2 1 
ATOM   4359 N  N   . ASN B 1 234 ? 81.52793  -44.01442 -13.39433 1.000 45.85859  ? 234 ASN B N   1 
ATOM   4360 C  CA  . ASN B 1 234 ? 80.80554  -42.75284 -13.24176 1.000 47.03300  ? 234 ASN B CA  1 
ATOM   4361 C  C   . ASN B 1 234 ? 79.98901  -42.77838 -11.94922 1.000 44.14095  ? 234 ASN B C   1 
ATOM   4362 O  O   . ASN B 1 234 ? 78.75638  -42.78566 -11.93316 1.000 45.61077  ? 234 ASN B O   1 
ATOM   4363 C  CB  . ASN B 1 234 ? 79.94436  -42.48184 -14.46650 1.000 48.08732  ? 234 ASN B CB  1 
ATOM   4364 C  CG  . ASN B 1 234 ? 80.77682  -42.16519 -15.69223 1.000 55.92672  ? 234 ASN B CG  1 
ATOM   4365 O  OD1 . ASN B 1 234 ? 81.98259  -41.91904 -15.59033 1.000 48.28809  ? 234 ASN B OD1 1 
ATOM   4366 N  ND2 . ASN B 1 234 ? 80.13979  -42.16231 -16.85800 1.000 46.97181  ? 234 ASN B ND2 1 
ATOM   4367 N  N   . ASN B 1 235 ? 80.73124  -42.81615 -10.84745 1.000 44.90151  ? 235 ASN B N   1 
ATOM   4368 C  CA  . ASN B 1 235 ? 80.23020  -42.58314 -9.50265  1.000 43.63023  ? 235 ASN B CA  1 
ATOM   4369 C  C   . ASN B 1 235 ? 81.10199  -41.49376 -8.89704  1.000 42.47714  ? 235 ASN B C   1 
ATOM   4370 O  O   . ASN B 1 235 ? 82.32207  -41.49867 -9.08916  1.000 42.16357  ? 235 ASN B O   1 
ATOM   4371 C  CB  . ASN B 1 235 ? 80.27957  -43.87133 -8.65206  1.000 44.36974  ? 235 ASN B CB  1 
ATOM   4372 C  CG  . ASN B 1 235 ? 79.76988  -43.66818 -7.23068  1.000 42.72861  ? 235 ASN B CG  1 
ATOM   4373 O  OD1 . ASN B 1 235 ? 80.34519  -42.90690 -6.45263  1.000 42.30793  ? 235 ASN B OD1 1 
ATOM   4374 N  ND2 . ASN B 1 235 ? 78.69901  -44.37428 -6.87951  1.000 40.04326  ? 235 ASN B ND2 1 
ATOM   4375 N  N   . MET B 1 236 ? 80.47848  -40.55288 -8.18006  1.000 40.05537  ? 236 MET B N   1 
ATOM   4376 C  CA  . MET B 1 236 ? 81.21978  -39.39320 -7.68632  1.000 42.37639  ? 236 MET B CA  1 
ATOM   4377 C  C   . MET B 1 236 ? 82.41694  -39.80718 -6.83682  1.000 42.80084  ? 236 MET B C   1 
ATOM   4378 O  O   . MET B 1 236 ? 83.46835  -39.15706 -6.87785  1.000 42.99986  ? 236 MET B O   1 
ATOM   4379 C  CB  . MET B 1 236 ? 80.29806  -38.46633 -6.88984  1.000 41.85732  ? 236 MET B CB  1 
ATOM   4380 C  CG  . MET B 1 236 ? 80.98529  -37.19327 -6.40037  1.000 40.26811  ? 236 MET B CG  1 
ATOM   4381 S  SD  . MET B 1 236 ? 81.54808  -36.11832 -7.74393  1.000 45.96849  ? 236 MET B SD  1 
ATOM   4382 C  CE  . MET B 1 236 ? 80.00905  -35.31950 -8.19771  1.000 44.72239  ? 236 MET B CE  1 
ATOM   4383 N  N   . VAL B 1 237 ? 82.28077  -40.89184 -6.06696  1.000 42.27718  ? 237 VAL B N   1 
ATOM   4384 C  CA  . VAL B 1 237 ? 83.39743  -41.37430 -5.25358  1.000 37.67391  ? 237 VAL B CA  1 
ATOM   4385 C  C   . VAL B 1 237 ? 84.57976  -41.74852 -6.14224  1.000 44.15766  ? 237 VAL B C   1 
ATOM   4386 O  O   . VAL B 1 237 ? 85.71925  -41.33313 -5.89956  1.000 42.12524  ? 237 VAL B O   1 
ATOM   4387 C  CB  . VAL B 1 237 ? 82.95765  -42.56293 -4.37871  1.000 42.35846  ? 237 VAL B CB  1 
ATOM   4388 C  CG1 . VAL B 1 237 ? 84.12958  -43.07302 -3.55073  1.000 45.87980  ? 237 VAL B CG1 1 
ATOM   4389 C  CG2 . VAL B 1 237 ? 81.79899  -42.17340 -3.47556  1.000 37.70256  ? 237 VAL B CG2 1 
ATOM   4390 N  N   . MET B 1 238 ? 84.32442  -42.53887 -7.18897  1.000 37.64711  ? 238 MET B N   1 
ATOM   4391 C  CA  . MET B 1 238 ? 85.40353  -42.95522 -8.08036  1.000 41.78298  ? 238 MET B CA  1 
ATOM   4392 C  C   . MET B 1 238 ? 85.96235  -41.77502 -8.86448  1.000 46.87295  ? 238 MET B C   1 
ATOM   4393 O  O   . MET B 1 238 ? 87.17491  -41.68989 -9.08828  1.000 44.25868  ? 238 MET B O   1 
ATOM   4394 C  CB  . MET B 1 238 ? 84.91338  -44.04256 -9.03805  1.000 43.96549  ? 238 MET B CB  1 
ATOM   4395 C  CG  . MET B 1 238 ? 84.80516  -45.42736 -8.41872  1.000 53.18874  ? 238 MET B CG  1 
ATOM   4396 S  SD  . MET B 1 238 ? 83.44261  -45.56441 -7.24997  1.000 51.22377  ? 238 MET B SD  1 
ATOM   4397 C  CE  . MET B 1 238 ? 82.43347  -46.81834 -8.04173  1.000 54.14887  ? 238 MET B CE  1 
ATOM   4398 N  N   . ILE B 1 239 ? 85.09374  -40.85463 -9.28614  1.000 42.68632  ? 239 ILE B N   1 
ATOM   4399 C  CA  . ILE B 1 239 ? 85.53544  -39.72262 -10.09557 1.000 43.95133  ? 239 ILE B CA  1 
ATOM   4400 C  C   . ILE B 1 239 ? 86.46180  -38.81774 -9.29338  1.000 45.03469  ? 239 ILE B C   1 
ATOM   4401 O  O   . ILE B 1 239 ? 87.49679  -38.36228 -9.79658  1.000 45.84100  ? 239 ILE B O   1 
ATOM   4402 C  CB  . ILE B 1 239 ? 84.31492  -38.95923 -10.64111 1.000 49.61185  ? 239 ILE B CB  1 
ATOM   4403 C  CG1 . ILE B 1 239 ? 83.57011  -39.83198 -11.65257 1.000 45.39662  ? 239 ILE B CG1 1 
ATOM   4404 C  CG2 . ILE B 1 239 ? 84.73564  -37.63027 -11.26001 1.000 45.97166  ? 239 ILE B CG2 1 
ATOM   4405 C  CD1 . ILE B 1 239 ? 82.15175  -39.40659 -11.89108 1.000 47.18424  ? 239 ILE B CD1 1 
ATOM   4406 N  N   . LEU B 1 240 ? 86.11421  -38.55226 -8.03066  1.000 44.16941  ? 240 LEU B N   1 
ATOM   4407 C  CA  . LEU B 1 240 ? 86.97689  -37.73122 -7.18717  1.000 47.71335  ? 240 LEU B CA  1 
ATOM   4408 C  C   . LEU B 1 240 ? 88.32162  -38.40172 -6.93850  1.000 55.35632  ? 240 LEU B C   1 
ATOM   4409 O  O   . LEU B 1 240 ? 89.33823  -37.71391 -6.78976  1.000 50.19464  ? 240 LEU B O   1 
ATOM   4410 C  CB  . LEU B 1 240 ? 86.28759  -37.42799 -5.85750  1.000 42.53077  ? 240 LEU B CB  1 
ATOM   4411 C  CG  . LEU B 1 240 ? 85.05878  -36.51860 -5.89995  1.000 47.35598  ? 240 LEU B CG  1 
ATOM   4412 C  CD1 . LEU B 1 240 ? 84.45699  -36.40114 -4.51114  1.000 43.14749  ? 240 LEU B CD1 1 
ATOM   4413 C  CD2 . LEU B 1 240 ? 85.41457  -35.14489 -6.45796  1.000 47.55950  ? 240 LEU B CD2 1 
ATOM   4414 N  N   . ARG B 1 241 ? 88.34909  -39.73561 -6.87736  1.000 48.26312  ? 241 ARG B N   1 
ATOM   4415 C  CA  . ARG B 1 241 ? 89.62318  -40.43994 -6.77895  1.000 49.03149  ? 241 ARG B CA  1 
ATOM   4416 C  C   . ARG B 1 241 ? 90.48210  -40.17723 -8.00869  1.000 50.27731  ? 241 ARG B C   1 
ATOM   4417 O  O   . ARG B 1 241 ? 91.67662  -39.88423 -7.89513  1.000 51.30450  ? 241 ARG B O   1 
ATOM   4418 C  CB  . ARG B 1 241 ? 89.39151  -41.94125 -6.60212  1.000 49.62686  ? 241 ARG B CB  1 
ATOM   4419 C  CG  . ARG B 1 241 ? 88.73461  -42.33459 -5.29217  1.000 48.06061  ? 241 ARG B CG  1 
ATOM   4420 C  CD  . ARG B 1 241 ? 88.88662  -43.82815 -5.05501  1.000 53.62470  ? 241 ARG B CD  1 
ATOM   4421 N  NE  . ARG B 1 241 ? 90.28222  -44.19505 -4.84503  1.000 48.14616  ? 241 ARG B NE  1 
ATOM   4422 C  CZ  . ARG B 1 241 ? 90.75854  -45.42901 -4.93910  1.000 60.09172  ? 241 ARG B CZ  1 
ATOM   4423 N  NH1 . ARG B 1 241 ? 89.97847  -46.45005 -5.25495  1.000 54.79053  ? 241 ARG B NH1 1 
ATOM   4424 N  NH2 . ARG B 1 241 ? 92.05211  -45.64314 -4.71708  1.000 60.81668  ? 241 ARG B NH2 1 
ATOM   4425 N  N   . ARG B 1 242 ? 89.88581  -40.27772 -9.19906  1.000 46.90638  ? 242 ARG B N   1 
ATOM   4426 C  CA  . ARG B 1 242 ? 90.63829  -40.04442 -10.42690 1.000 47.60722  ? 242 ARG B CA  1 
ATOM   4427 C  C   . ARG B 1 242 ? 91.03051  -38.57877 -10.56331 1.000 58.51397  ? 242 ARG B C   1 
ATOM   4428 O  O   . ARG B 1 242 ? 92.18476  -38.26126 -10.87500 1.000 61.35571  ? 242 ARG B O   1 
ATOM   4429 C  CB  . ARG B 1 242 ? 89.82204  -40.48895 -11.64207 1.000 51.65701  ? 242 ARG B CB  1 
ATOM   4430 C  CG  . ARG B 1 242 ? 89.47156  -41.96343 -11.65658 1.000 53.04481  ? 242 ARG B CG  1 
ATOM   4431 C  CD  . ARG B 1 242 ? 89.02672  -42.42074 -13.03959 1.000 53.49498  ? 242 ARG B CD  1 
ATOM   4432 N  NE  . ARG B 1 242 ? 87.85134  -41.70343 -13.52021 1.000 52.17799  ? 242 ARG B NE  1 
ATOM   4433 C  CZ  . ARG B 1 242 ? 86.60152  -42.02684 -13.21545 1.000 51.40288  ? 242 ARG B CZ  1 
ATOM   4434 N  NH1 . ARG B 1 242 ? 86.32660  -43.03221 -12.39954 1.000 50.42581  ? 242 ARG B NH1 1 
ATOM   4435 N  NH2 . ARG B 1 242 ? 85.60232  -41.32509 -13.74301 1.000 51.63498  ? 242 ARG B NH2 1 
ATOM   4436 N  N   . GLU B 1 243 ? 90.07969  -37.66962 -10.32860 1.000 57.62627  ? 243 GLU B N   1 
ATOM   4437 C  CA  . GLU B 1 243 ? 90.32671  -36.25359 -10.58578 1.000 54.09798  ? 243 GLU B CA  1 
ATOM   4438 C  C   . GLU B 1 243 ? 91.47433  -35.71767 -9.73722  1.000 57.66407  ? 243 GLU B C   1 
ATOM   4439 O  O   . GLU B 1 243 ? 92.33488  -34.98474 -10.23879 1.000 59.51495  ? 243 GLU B O   1 
ATOM   4440 C  CB  . GLU B 1 243 ? 89.05654  -35.44042 -10.33300 1.000 54.25619  ? 243 GLU B CB  1 
ATOM   4441 C  CG  . GLU B 1 243 ? 89.22438  -33.94722 -10.59419 1.000 55.83715  ? 243 GLU B CG  1 
ATOM   4442 C  CD  . GLU B 1 243 ? 87.92707  -33.16702 -10.45198 1.000 61.48994  ? 243 GLU B CD  1 
ATOM   4443 O  OE1 . GLU B 1 243 ? 86.93773  -33.73183 -9.93745  1.000 57.10595  ? 243 GLU B OE1 1 
ATOM   4444 O  OE2 . GLU B 1 243 ? 87.89553  -31.98458 -10.85769 1.000 55.91183  ? 243 GLU B OE2 1 
ATOM   4445 N  N   . HIS B 1 244 ? 91.51205  -36.07763 -8.45333  1.000 50.02231  ? 244 HIS B N   1 
ATOM   4446 C  CA  . HIS B 1 244 ? 92.47298  -35.50388 -7.52189  1.000 57.13223  ? 244 HIS B CA  1 
ATOM   4447 C  C   . HIS B 1 244 ? 93.53290  -36.48149 -7.03640  1.000 57.50950  ? 244 HIS B C   1 
ATOM   4448 O  O   . HIS B 1 244 ? 94.46160  -36.05752 -6.34005  1.000 62.27299  ? 244 HIS B O   1 
ATOM   4449 C  CB  . HIS B 1 244 ? 91.74572  -34.92445 -6.29950  1.000 54.20280  ? 244 HIS B CB  1 
ATOM   4450 C  CG  . HIS B 1 244 ? 90.72063  -33.88951 -6.64010  1.000 59.33017  ? 244 HIS B CG  1 
ATOM   4451 N  ND1 . HIS B 1 244 ? 89.47407  -33.85894 -6.05384  1.000 62.47092  ? 244 HIS B ND1 1 
ATOM   4452 C  CD2 . HIS B 1 244 ? 90.75608  -32.84755 -7.50388  1.000 54.86585  ? 244 HIS B CD2 1 
ATOM   4453 C  CE1 . HIS B 1 244 ? 88.78435  -32.84465 -6.54359  1.000 60.07166  ? 244 HIS B CE1 1 
ATOM   4454 N  NE2 . HIS B 1 244 ? 89.53866  -32.21597 -7.42666  1.000 57.32836  ? 244 HIS B NE2 1 
ATOM   4455 N  N   . GLY B 1 245 ? 93.42674  -37.76374 -7.37183  1.000 57.96416  ? 245 GLY B N   1 
ATOM   4456 C  CA  . GLY B 1 245 ? 94.35288  -38.74228 -6.83761  1.000 52.58565  ? 245 GLY B CA  1 
ATOM   4457 C  C   . GLY B 1 245 ? 94.13398  -38.96973 -5.35766  1.000 49.70646  ? 245 GLY B C   1 
ATOM   4458 O  O   . GLY B 1 245 ? 95.06844  -38.84798 -4.56017  1.000 53.52032  ? 245 GLY B O   1 
ATOM   4459 N  N   . TRP B 1 246 ? 92.89892  -39.29268 -4.98010  1.000 50.17742  ? 246 TRP B N   1 
ATOM   4460 C  CA  . TRP B 1 246 ? 92.50578  -39.45495 -3.58801  1.000 52.65543  ? 246 TRP B CA  1 
ATOM   4461 C  C   . TRP B 1 246 ? 92.17244  -40.90840 -3.28048  1.000 49.87521  ? 246 TRP B C   1 
ATOM   4462 O  O   . TRP B 1 246 ? 91.76358  -41.67258 -4.15912  1.000 50.26520  ? 246 TRP B O   1 
ATOM   4463 C  CB  . TRP B 1 246 ? 91.28079  -38.59986 -3.24992  1.000 58.42267  ? 246 TRP B CB  1 
ATOM   4464 C  CG  . TRP B 1 246 ? 91.52713  -37.13308 -3.11722  1.000 63.70830  ? 246 TRP B CG  1 
ATOM   4465 C  CD1 . TRP B 1 246 ? 92.73151  -36.49490 -3.08273  1.000 63.92298  ? 246 TRP B CD1 1 
ATOM   4466 C  CD2 . TRP B 1 246 ? 90.52886  -36.11604 -2.99507  1.000 63.97623  ? 246 TRP B CD2 1 
ATOM   4467 N  NE1 . TRP B 1 246 ? 92.54339  -35.13898 -2.94917  1.000 62.08658  ? 246 TRP B NE1 1 
ATOM   4468 C  CE2 . TRP B 1 246 ? 91.19859  -34.88182 -2.89337  1.000 63.50944  ? 246 TRP B CE2 1 
ATOM   4469 C  CE3 . TRP B 1 246 ? 89.13149  -36.13048 -2.96470  1.000 55.72376  ? 246 TRP B CE3 1 
ATOM   4470 C  CZ2 . TRP B 1 246 ? 90.51815  -33.67285 -2.76395  1.000 59.77724  ? 246 TRP B CZ2 1 
ATOM   4471 C  CZ3 . TRP B 1 246 ? 88.45954  -34.93203 -2.83761  1.000 60.78219  ? 246 TRP B CZ3 1 
ATOM   4472 C  CH2 . TRP B 1 246 ? 89.15212  -33.71922 -2.73701  1.000 61.51490  ? 246 TRP B CH2 1 
ATOM   4473 N  N   . SER B 1 247 ? 92.32363  -41.27312 -2.01123  1.000 53.26049  ? 247 SER B N   1 
ATOM   4474 C  CA  . SER B 1 247 ? 91.83559  -42.55800 -1.54096  1.000 53.87210  ? 247 SER B CA  1 
ATOM   4475 C  C   . SER B 1 247 ? 90.30834  -42.54409 -1.48063  1.000 55.75016  ? 247 SER B C   1 
ATOM   4476 O  O   . SER B 1 247 ? 89.66436  -41.49637 -1.58577  1.000 52.09713  ? 247 SER B O   1 
ATOM   4477 C  CB  . SER B 1 247 ? 92.41743  -42.88070 -0.16733  1.000 50.67746  ? 247 SER B CB  1 
ATOM   4478 O  OG  . SER B 1 247 ? 91.94626  -41.96301 0.80434   1.000 60.83568  ? 247 SER B OG  1 
ATOM   4479 N  N   . LYS B 1 248 ? 89.72257  -43.73214 -1.31057  1.000 56.04737  ? 248 LYS B N   1 
ATOM   4480 C  CA  . LYS B 1 248 ? 88.26661  -43.82340 -1.26323  1.000 54.29505  ? 248 LYS B CA  1 
ATOM   4481 C  C   . LYS B 1 248 ? 87.70682  -43.07098 -0.06335  1.000 50.76084  ? 248 LYS B C   1 
ATOM   4482 O  O   . LYS B 1 248 ? 86.71097  -42.34848 -0.18365  1.000 48.85527  ? 248 LYS B O   1 
ATOM   4483 C  CB  . LYS B 1 248 ? 87.81915  -45.28524 -1.22667  1.000 56.38842  ? 248 LYS B CB  1 
ATOM   4484 C  CG  . LYS B 1 248 ? 86.30791  -45.44738 -1.32142  1.000 54.19446  ? 248 LYS B CG  1 
ATOM   4485 C  CD  . LYS B 1 248 ? 85.80444  -46.70248 -0.62199  1.000 59.97001  ? 248 LYS B CD  1 
ATOM   4486 C  CE  . LYS B 1 248 ? 86.04186  -47.95077 -1.45193  1.000 74.93753  ? 248 LYS B CE  1 
ATOM   4487 N  NZ  . LYS B 1 248 ? 85.34963  -49.13380 -0.86031  1.000 77.53193  ? 248 LYS B NZ  1 
ATOM   4488 N  N   . SER B 1 249 ? 88.33920  -43.21983 1.10262   1.000 56.53225  ? 249 SER B N   1 
ATOM   4489 C  CA  . SER B 1 249 ? 87.82698  -42.57008 2.30368   1.000 53.53423  ? 249 SER B CA  1 
ATOM   4490 C  C   . SER B 1 249 ? 87.98193  -41.05506 2.23784   1.000 53.58772  ? 249 SER B C   1 
ATOM   4491 O  O   . SER B 1 249 ? 87.14766  -40.32697 2.78748   1.000 49.51563  ? 249 SER B O   1 
ATOM   4492 C  CB  . SER B 1 249 ? 88.52681  -43.12893 3.54259   1.000 55.91264  ? 249 SER B CB  1 
ATOM   4493 O  OG  . SER B 1 249 ? 89.92143  -42.89641 3.48366   1.000 66.97304  ? 249 SER B OG  1 
ATOM   4494 N  N   . ARG B 1 250 ? 89.03112  -40.55994 1.57480   1.000 49.85104  ? 250 ARG B N   1 
ATOM   4495 C  CA  . ARG B 1 250 ? 89.17309  -39.11603 1.41410   1.000 53.24427  ? 250 ARG B CA  1 
ATOM   4496 C  C   . ARG B 1 250 ? 88.10518  -38.55965 0.48106   1.000 52.21792  ? 250 ARG B C   1 
ATOM   4497 O  O   . ARG B 1 250 ? 87.58614  -37.46115 0.70975   1.000 53.69330  ? 250 ARG B O   1 
ATOM   4498 C  CB  . ARG B 1 250 ? 90.57198  -38.76714 0.90202   1.000 55.29973  ? 250 ARG B CB  1 
ATOM   4499 C  CG  . ARG B 1 250 ? 90.71210  -37.31378 0.46561   1.000 62.65105  ? 250 ARG B CG  1 
ATOM   4500 C  CD  . ARG B 1 250 ? 92.16039  -36.85892 0.37573   1.000 69.29898  ? 250 ARG B CD  1 
ATOM   4501 N  NE  . ARG B 1 250 ? 92.83483  -36.92373 1.66634   1.000 81.72524  ? 250 ARG B NE  1 
ATOM   4502 C  CZ  . ARG B 1 250 ? 94.00731  -37.50791 1.86956   1.000 82.26441  ? 250 ARG B CZ  1 
ATOM   4503 N  NH1 . ARG B 1 250 ? 94.68624  -38.05805 0.87696   1.000 79.66829  ? 250 ARG B NH1 1 
ATOM   4504 N  NH2 . ARG B 1 250 ? 94.51688  -37.53044 3.09759   1.000 89.85204  ? 250 ARG B NH2 1 
ATOM   4505 N  N   . SER B 1 251 ? 87.75668  -39.30644 -0.56959  1.000 46.92936  ? 251 SER B N   1 
ATOM   4506 C  CA  . SER B 1 251 ? 86.70887  -38.85776 -1.48174  1.000 50.06721  ? 251 SER B CA  1 
ATOM   4507 C  C   . SER B 1 251 ? 85.34989  -38.82083 -0.79350  1.000 51.72916  ? 251 SER B C   1 
ATOM   4508 O  O   . SER B 1 251 ? 84.56782  -37.88541 -1.00227  1.000 50.46896  ? 251 SER B O   1 
ATOM   4509 C  CB  . SER B 1 251 ? 86.66259  -39.76483 -2.70810  1.000 45.75715  ? 251 SER B CB  1 
ATOM   4510 O  OG  . SER B 1 251 ? 87.93213  -39.81473 -3.33078  1.000 57.06622  ? 251 SER B OG  1 
ATOM   4511 N  N   . VAL B 1 252 ? 85.04820  -39.83198 0.02415   1.000 44.38789  ? 252 VAL B N   1 
ATOM   4512 C  CA  . VAL B 1 252 ? 83.78851  -39.83793 0.76229   1.000 48.69428  ? 252 VAL B CA  1 
ATOM   4513 C  C   . VAL B 1 252 ? 83.74332  -38.67585 1.74435   1.000 47.97535  ? 252 VAL B C   1 
ATOM   4514 O  O   . VAL B 1 252 ? 82.71860  -37.99476 1.87565   1.000 46.43972  ? 252 VAL B O   1 
ATOM   4515 C  CB  . VAL B 1 252 ? 83.59181  -41.18908 1.47484   1.000 50.41435  ? 252 VAL B CB  1 
ATOM   4516 C  CG1 . VAL B 1 252 ? 82.31662  -41.17790 2.30239   1.000 44.81286  ? 252 VAL B CG1 1 
ATOM   4517 C  CG2 . VAL B 1 252 ? 83.55607  -42.31863 0.46186   1.000 47.89909  ? 252 VAL B CG2 1 
ATOM   4518 N  N   . SER B 1 253 ? 84.85301  -38.42981 2.44789   1.000 48.95737  ? 253 SER B N   1 
ATOM   4519 C  CA  . SER B 1 253 ? 84.90114  -37.31757 3.39243   1.000 52.42619  ? 253 SER B CA  1 
ATOM   4520 C  C   . SER B 1 253 ? 84.68564  -35.98730 2.68378   1.000 50.67880  ? 253 SER B C   1 
ATOM   4521 O  O   . SER B 1 253 ? 83.98111  -35.10933 3.19508   1.000 49.91059  ? 253 SER B O   1 
ATOM   4522 C  CB  . SER B 1 253 ? 86.23548  -37.31577 4.14047   1.000 53.79064  ? 253 SER B CB  1 
ATOM   4523 O  OG  . SER B 1 253 ? 86.36980  -38.46428 4.95968   1.000 67.72062  ? 253 SER B OG  1 
ATOM   4524 N  N   . HIS B 1 254 ? 85.28602  -35.82241 1.50300   1.000 49.13647  ? 254 HIS B N   1 
ATOM   4525 C  CA  . HIS B 1 254 ? 85.05325  -34.61943 0.71128   1.000 52.14028  ? 254 HIS B CA  1 
ATOM   4526 C  C   . HIS B 1 254 ? 83.57719  -34.46690 0.36456   1.000 52.34969  ? 254 HIS B C   1 
ATOM   4527 O  O   . HIS B 1 254 ? 83.02250  -33.36434 0.44996   1.000 48.28986  ? 254 HIS B O   1 
ATOM   4528 C  CB  . HIS B 1 254 ? 85.90287  -34.66269 -0.55831  1.000 44.22141  ? 254 HIS B CB  1 
ATOM   4529 C  CG  . HIS B 1 254 ? 85.66670  -33.51363 -1.48895  1.000 49.10148  ? 254 HIS B CG  1 
ATOM   4530 N  ND1 . HIS B 1 254 ? 86.15493  -32.24762 -1.24796  1.000 48.45188  ? 254 HIS B ND1 1 
ATOM   4531 C  CD2 . HIS B 1 254 ? 85.00084  -33.44169 -2.66606  1.000 46.15118  ? 254 HIS B CD2 1 
ATOM   4532 C  CE1 . HIS B 1 254 ? 85.79725  -31.44464 -2.23369  1.000 49.70578  ? 254 HIS B CE1 1 
ATOM   4533 N  NE2 . HIS B 1 254 ? 85.09628  -32.14431 -3.10754  1.000 57.03005  ? 254 HIS B NE2 1 
ATOM   4534 N  N   . MET B 1 255 ? 82.92234  -35.56772 -0.01919  1.000 45.79153  ? 255 MET B N   1 
ATOM   4535 C  CA  . MET B 1 255 ? 81.50582  -35.50713 -0.36785  1.000 47.00758  ? 255 MET B CA  1 
ATOM   4536 C  C   . MET B 1 255 ? 80.64442  -35.17250 0.84557   1.000 45.33124  ? 255 MET B C   1 
ATOM   4537 O  O   . MET B 1 255 ? 79.62970  -34.47703 0.71968   1.000 44.98445  ? 255 MET B O   1 
ATOM   4538 C  CB  . MET B 1 255 ? 81.06977  -36.82713 -0.99905  1.000 40.99457  ? 255 MET B CB  1 
ATOM   4539 C  CG  . MET B 1 255 ? 81.67304  -37.06570 -2.37155  1.000 42.57144  ? 255 MET B CG  1 
ATOM   4540 S  SD  . MET B 1 255 ? 81.36220  -38.72097 -3.01646  1.000 44.85283  ? 255 MET B SD  1 
ATOM   4541 C  CE  . MET B 1 255 ? 79.57087  -38.74461 -3.02788  1.000 40.33179  ? 255 MET B CE  1 
ATOM   4542 N  N   . GLN B 1 256 ? 81.02847  -35.65962 2.02835   1.000 47.42268  ? 256 GLN B N   1 
ATOM   4543 C  CA  . GLN B 1 256 ? 80.34805  -35.24905 3.25438   1.000 49.91525  ? 256 GLN B CA  1 
ATOM   4544 C  C   . GLN B 1 256 ? 80.49744  -33.75118 3.48207   1.000 44.30687  ? 256 GLN B C   1 
ATOM   4545 O  O   . GLN B 1 256 ? 79.52633  -33.06088 3.81347   1.000 43.15946  ? 256 GLN B O   1 
ATOM   4546 C  CB  . GLN B 1 256 ? 80.89780  -36.02343 4.45172   1.000 49.17759  ? 256 GLN B CB  1 
ATOM   4547 C  CG  . GLN B 1 256 ? 80.40934  -37.45219 4.56482   1.000 54.86305  ? 256 GLN B CG  1 
ATOM   4548 C  CD  . GLN B 1 256 ? 81.03789  -38.17386 5.73939   1.000 59.60675  ? 256 GLN B CD  1 
ATOM   4549 O  OE1 . GLN B 1 256 ? 82.23943  -38.43999 5.74566   1.000 64.08538  ? 256 GLN B OE1 1 
ATOM   4550 N  NE2 . GLN B 1 256 ? 80.23039  -38.48315 6.74726   1.000 53.31792  ? 256 GLN B NE2 1 
ATOM   4551 N  N   . ASN B 1 257 ? 81.71766  -33.23253 3.31351   1.000 45.96776  ? 257 ASN B N   1 
ATOM   4552 C  CA  . ASN B 1 257 ? 81.93788  -31.79474 3.43451   1.000 50.08000  ? 257 ASN B CA  1 
ATOM   4553 C  C   . ASN B 1 257 ? 81.12351  -31.02008 2.40525   1.000 46.90880  ? 257 ASN B C   1 
ATOM   4554 O  O   . ASN B 1 257 ? 80.58384  -29.94974 2.70827   1.000 43.45482  ? 257 ASN B O   1 
ATOM   4555 C  CB  . ASN B 1 257 ? 83.42466  -31.47253 3.27984   1.000 49.45219  ? 257 ASN B CB  1 
ATOM   4556 C  CG  . ASN B 1 257 ? 84.26475  -32.02691 4.41285   1.000 59.11723  ? 257 ASN B CG  1 
ATOM   4557 O  OD1 . ASN B 1 257 ? 83.74471  -32.38564 5.47118   1.000 63.21252  ? 257 ASN B OD1 1 
ATOM   4558 N  ND2 . ASN B 1 257 ? 85.57532  -32.09107 4.20006   1.000 59.34768  ? 257 ASN B ND2 1 
ATOM   4559 N  N   . GLU B 1 258 ? 81.02362  -31.54342 1.18052   1.000 39.79395  ? 258 GLU B N   1 
ATOM   4560 C  CA  . GLU B 1 258 ? 80.29933  -30.82588 0.13697   1.000 40.64923  ? 258 GLU B CA  1 
ATOM   4561 C  C   . GLU B 1 258 ? 78.80588  -30.78082 0.43038   1.000 42.82003  ? 258 GLU B C   1 
ATOM   4562 O  O   . GLU B 1 258 ? 78.15638  -29.75672 0.19605   1.000 44.43986  ? 258 GLU B O   1 
ATOM   4563 C  CB  . GLU B 1 258 ? 80.56807  -31.45999 -1.22962  1.000 47.10221  ? 258 GLU B CB  1 
ATOM   4564 C  CG  . GLU B 1 258 ? 81.92373  -31.08885 -1.81827  1.000 49.25004  ? 258 GLU B CG  1 
ATOM   4565 C  CD  . GLU B 1 258 ? 82.07134  -29.58904 -2.02941  1.000 60.55176  ? 258 GLU B CD  1 
ATOM   4566 O  OE1 . GLU B 1 258 ? 81.05232  -28.92915 -2.32531  1.000 68.15299  ? 258 GLU B OE1 1 
ATOM   4567 O  OE2 . GLU B 1 258 ? 83.19912  -29.06581 -1.89518  1.000 55.15802  ? 258 GLU B OE2 1 
ATOM   4568 N  N   . VAL B 1 259 ? 78.24210  -31.87589 0.94587   1.000 40.32917  ? 259 VAL B N   1 
ATOM   4569 C  CA  . VAL B 1 259 ? 76.83403  -31.86050 1.33269   1.000 41.18674  ? 259 VAL B CA  1 
ATOM   4570 C  C   . VAL B 1 259 ? 76.60252  -30.83235 2.43039   1.000 42.81193  ? 259 VAL B C   1 
ATOM   4571 O  O   . VAL B 1 259 ? 75.63198  -30.06472 2.39028   1.000 41.17187  ? 259 VAL B O   1 
ATOM   4572 C  CB  . VAL B 1 259 ? 76.37704  -33.26609 1.76579   1.000 45.52701  ? 259 VAL B CB  1 
ATOM   4573 C  CG1 . VAL B 1 259 ? 75.03336  -33.19139 2.48297   1.000 36.51671  ? 259 VAL B CG1 1 
ATOM   4574 C  CG2 . VAL B 1 259 ? 76.29004  -34.18890 0.55851   1.000 42.14922  ? 259 VAL B CG2 1 
ATOM   4575 N  N   . ARG B 1 260 ? 77.50092  -30.79071 3.41779   1.000 42.80960  ? 260 ARG B N   1 
ATOM   4576 C  CA  . ARG B 1 260 ? 77.38627  -29.81471 4.49682   1.000 43.69822  ? 260 ARG B CA  1 
ATOM   4577 C  C   . ARG B 1 260 ? 77.45990  -28.38988 3.96116   1.000 43.67464  ? 260 ARG B C   1 
ATOM   4578 O  O   . ARG B 1 260 ? 76.60390  -27.55320 4.26881   1.000 43.56247  ? 260 ARG B O   1 
ATOM   4579 C  CB  . ARG B 1 260 ? 78.48496  -30.05425 5.52977   1.000 41.86871  ? 260 ARG B CB  1 
ATOM   4580 C  CG  . ARG B 1 260 ? 78.59259  -28.96345 6.58416   1.000 52.84694  ? 260 ARG B CG  1 
ATOM   4581 C  CD  . ARG B 1 260 ? 79.83829  -29.15498 7.43655   1.000 54.46404  ? 260 ARG B CD  1 
ATOM   4582 N  NE  . ARG B 1 260 ? 81.05344  -29.09698 6.63234   1.000 72.99469  ? 260 ARG B NE  1 
ATOM   4583 C  CZ  . ARG B 1 260 ? 82.25682  -29.45934 7.05727   1.000 77.66400  ? 260 ARG B CZ  1 
ATOM   4584 N  NH1 . ARG B 1 260 ? 82.44662  -29.93617 8.27722   1.000 84.62747  ? 260 ARG B NH1 1 
ATOM   4585 N  NH2 . ARG B 1 260 ? 83.29669  -29.34151 6.23687   1.000 74.53241  ? 260 ARG B NH2 1 
ATOM   4586 N  N   . ALA B 1 261 ? 78.48271  -28.09760 3.15363   1.000 42.29532  ? 261 ALA B N   1 
ATOM   4587 C  CA  . ALA B 1 261 ? 78.65507  -26.74841 2.62506   1.000 40.53937  ? 261 ALA B CA  1 
ATOM   4588 C  C   . ALA B 1 261 ? 77.45420  -26.31518 1.79357   1.000 38.34656  ? 261 ALA B C   1 
ATOM   4589 O  O   . ALA B 1 261 ? 77.06930  -25.14093 1.81226   1.000 42.07950  ? 261 ALA B O   1 
ATOM   4590 C  CB  . ALA B 1 261 ? 79.93628  -26.67170 1.79403   1.000 40.81999  ? 261 ALA B CB  1 
ATOM   4591 N  N   . ARG B 1 262 ? 76.84124  -27.24745 1.06347   1.000 41.09856  ? 262 ARG B N   1 
ATOM   4592 C  CA  . ARG B 1 262 ? 75.71080  -26.87966 0.21975   1.000 40.63429  ? 262 ARG B CA  1 
ATOM   4593 C  C   . ARG B 1 262 ? 74.42911  -26.69574 1.02079   1.000 38.95957  ? 262 ARG B C   1 
ATOM   4594 O  O   . ARG B 1 262 ? 73.59500  -25.86100 0.65387   1.000 38.92367  ? 262 ARG B O   1 
ATOM   4595 C  CB  . ARG B 1 262 ? 75.52764  -27.91869 -0.88623  1.000 45.44436  ? 262 ARG B CB  1 
ATOM   4596 C  CG  . ARG B 1 262 ? 76.74261  -27.96783 -1.79104  1.000 52.33055  ? 262 ARG B CG  1 
ATOM   4597 C  CD  . ARG B 1 262 ? 76.54277  -28.74012 -3.07669  1.000 57.05890  ? 262 ARG B CD  1 
ATOM   4598 N  NE  . ARG B 1 262 ? 77.80110  -28.79524 -3.81220  1.000 63.89694  ? 262 ARG B NE  1 
ATOM   4599 C  CZ  . ARG B 1 262 ? 78.34852  -27.76079 -4.43962  1.000 69.32934  ? 262 ARG B CZ  1 
ATOM   4600 N  NH1 . ARG B 1 262 ? 77.74905  -26.58044 -4.48800  1.000 61.00580  ? 262 ARG B NH1 1 
ATOM   4601 N  NH2 . ARG B 1 262 ? 79.53194  -27.91031 -5.02710  1.000 63.76070  ? 262 ARG B NH2 1 
ATOM   4602 N  N   . LEU B 1 263 ? 74.25511  -27.44391 2.11345   1.000 41.38913  ? 263 LEU B N   1 
ATOM   4603 C  CA  . LEU B 1 263 ? 73.11355  -27.19646 2.98950   1.000 41.57064  ? 263 LEU B CA  1 
ATOM   4604 C  C   . LEU B 1 263 ? 73.22303  -25.83075 3.65611   1.000 38.63960  ? 263 LEU B C   1 
ATOM   4605 O  O   . LEU B 1 263 ? 72.22678  -25.10836 3.77707   1.000 39.60637  ? 263 LEU B O   1 
ATOM   4606 C  CB  . LEU B 1 263 ? 72.99692  -28.30155 4.03954   1.000 41.49502  ? 263 LEU B CB  1 
ATOM   4607 C  CG  . LEU B 1 263 ? 71.93413  -29.36425 3.75106   1.000 48.91834  ? 263 LEU B CG  1 
ATOM   4608 C  CD1 . LEU B 1 263 ? 70.57124  -28.71413 3.57850   1.000 45.35505  ? 263 LEU B CD1 1 
ATOM   4609 C  CD2 . LEU B 1 263 ? 72.29789  -30.16657 2.51849   1.000 48.83146  ? 263 LEU B CD2 1 
ATOM   4610 N  N   . GLU B 1 264 ? 74.43007  -25.45333 4.08386   1.000 38.70036  ? 264 GLU B N   1 
ATOM   4611 C  CA  . GLU B 1 264 ? 74.62124  -24.13106 4.66958   1.000 38.49466  ? 264 GLU B CA  1 
ATOM   4612 C  C   . GLU B 1 264 ? 74.39088  -23.03548 3.63767   1.000 43.65508  ? 264 GLU B C   1 
ATOM   4613 O  O   . GLU B 1 264 ? 73.79744  -21.99668 3.94793   1.000 45.76615  ? 264 GLU B O   1 
ATOM   4614 C  CB  . GLU B 1 264 ? 76.01978  -24.02078 5.27300   1.000 37.41931  ? 264 GLU B CB  1 
ATOM   4615 C  CG  . GLU B 1 264 ? 76.24560  -24.92176 6.47905   1.000 44.82665  ? 264 GLU B CG  1 
ATOM   4616 C  CD  . GLU B 1 264 ? 75.34244  -24.58097 7.65844   1.000 56.05096  ? 264 GLU B CD  1 
ATOM   4617 O  OE1 . GLU B 1 264 ? 74.84342  -23.43472 7.74095   1.000 53.93758  ? 264 GLU B OE1 1 
ATOM   4618 O  OE2 . GLU B 1 264 ? 75.13481  -25.46713 8.51340   1.000 64.59998  ? 264 GLU B OE2 1 
ATOM   4619 N  N   . GLN B 1 265 ? 74.85211  -23.24877 2.40183   1.000 42.27188  ? 265 GLN B N   1 
ATOM   4620 C  CA  . GLN B 1 265 ? 74.55166  -22.30079 1.33349   1.000 39.89234  ? 265 GLN B CA  1 
ATOM   4621 C  C   . GLN B 1 265 ? 73.06192  -22.27398 1.02476   1.000 38.13752  ? 265 GLN B C   1 
ATOM   4622 O  O   . GLN B 1 265 ? 72.51162  -21.21550 0.69867   1.000 39.66417  ? 265 GLN B O   1 
ATOM   4623 C  CB  . GLN B 1 265 ? 75.34799  -22.64465 0.07610   1.000 36.48306  ? 265 GLN B CB  1 
ATOM   4624 C  CG  . GLN B 1 265 ? 76.82812  -22.36155 0.18051   1.000 38.13078  ? 265 GLN B CG  1 
ATOM   4625 C  CD  . GLN B 1 265 ? 77.58944  -22.85835 -1.02635  1.000 43.78917  ? 265 GLN B CD  1 
ATOM   4626 O  OE1 . GLN B 1 265 ? 77.60451  -22.21235 -2.07550  1.000 40.46916  ? 265 GLN B OE1 1 
ATOM   4627 N  NE2 . GLN B 1 265 ? 78.22158  -24.01969 -0.88851  1.000 41.90865  ? 265 GLN B NE2 1 
ATOM   4628 N  N   . TYR B 1 266 ? 72.39312  -23.42673 1.11939   1.000 36.72367  ? 266 TYR B N   1 
ATOM   4629 C  CA  . TYR B 1 266 ? 70.95395  -23.45967 0.88280   1.000 41.86070  ? 266 TYR B CA  1 
ATOM   4630 C  C   . TYR B 1 266 ? 70.21757  -22.54268 1.85336   1.000 43.28647  ? 266 TYR B C   1 
ATOM   4631 O  O   . TYR B 1 266 ? 69.30683  -21.80434 1.45868   1.000 42.99125  ? 266 TYR B O   1 
ATOM   4632 C  CB  . TYR B 1 266 ? 70.41778  -24.88755 0.99454   1.000 37.92532  ? 266 TYR B CB  1 
ATOM   4633 C  CG  . TYR B 1 266 ? 68.91208  -24.91351 0.89322   1.000 44.00269  ? 266 TYR B CG  1 
ATOM   4634 C  CD1 . TYR B 1 266 ? 68.28321  -24.81811 -0.33999  1.000 39.92608  ? 266 TYR B CD1 1 
ATOM   4635 C  CD2 . TYR B 1 266 ? 68.11731  -24.99510 2.02987   1.000 42.28227  ? 266 TYR B CD2 1 
ATOM   4636 C  CE1 . TYR B 1 266 ? 66.90659  -24.81804 -0.44224  1.000 45.63113  ? 266 TYR B CE1 1 
ATOM   4637 C  CE2 . TYR B 1 266 ? 66.73857  -24.99692 1.93696   1.000 43.79556  ? 266 TYR B CE2 1 
ATOM   4638 C  CZ  . TYR B 1 266 ? 66.13789  -24.90503 0.69857   1.000 48.58101  ? 266 TYR B CZ  1 
ATOM   4639 O  OH  . TYR B 1 266 ? 64.76546  -24.90632 0.59802   1.000 47.46515  ? 266 TYR B OH  1 
ATOM   4640 N  N   . LEU B 1 267 ? 70.59160  -22.58826 3.13586   1.000 43.15052  ? 267 LEU B N   1 
ATOM   4641 C  CA  . LEU B 1 267 ? 69.95048  -21.72757 4.12644   1.000 43.68248  ? 267 LEU B CA  1 
ATOM   4642 C  C   . LEU B 1 267 ? 70.22266  -20.25454 3.83920   1.000 45.24287  ? 267 LEU B C   1 
ATOM   4643 O  O   . LEU B 1 267 ? 69.33620  -19.40980 4.01207   1.000 47.92951  ? 267 LEU B O   1 
ATOM   4644 C  CB  . LEU B 1 267 ? 70.42284  -22.10335 5.53069   1.000 37.63259  ? 267 LEU B CB  1 
ATOM   4645 C  CG  . LEU B 1 267 ? 70.06557  -23.51139 6.01511   1.000 44.55501  ? 267 LEU B CG  1 
ATOM   4646 C  CD1 . LEU B 1 267 ? 70.71929  -23.79816 7.35853   1.000 45.15029  ? 267 LEU B CD1 1 
ATOM   4647 C  CD2 . LEU B 1 267 ? 68.55952  -23.68599 6.11377   1.000 43.41317  ? 267 LEU B CD2 1 
ATOM   4648 N  N   . LEU B 1 268 ? 71.44186  -19.92668 3.39395   1.000 43.78435  ? 268 LEU B N   1 
ATOM   4649 C  CA  . LEU B 1 268 ? 71.73059  -18.55799 2.97028   1.000 44.03075  ? 268 LEU B CA  1 
ATOM   4650 C  C   . LEU B 1 268 ? 70.80970  -18.12233 1.83744   1.000 47.12814  ? 268 LEU B C   1 
ATOM   4651 O  O   . LEU B 1 268 ? 70.29457  -16.99823 1.84348   1.000 48.63426  ? 268 LEU B O   1 
ATOM   4652 C  CB  . LEU B 1 268 ? 73.18549  -18.42809 2.52184   1.000 44.41573  ? 268 LEU B CB  1 
ATOM   4653 C  CG  . LEU B 1 268 ? 74.34208  -18.58689 3.50544   1.000 55.08026  ? 268 LEU B CG  1 
ATOM   4654 C  CD1 . LEU B 1 268 ? 75.64958  -18.20703 2.81053   1.000 50.71706  ? 268 LEU B CD1 1 
ATOM   4655 C  CD2 . LEU B 1 268 ? 74.11891  -17.75163 4.75956   1.000 57.68086  ? 268 LEU B CD2 1 
ATOM   4656 N  N   . LEU B 1 269 ? 70.60208  -18.99539 0.84761   1.000 41.88271  ? 269 LEU B N   1 
ATOM   4657 C  CA  . LEU B 1 269 ? 69.77751  -18.63137 -0.30063  1.000 45.73515  ? 269 LEU B CA  1 
ATOM   4658 C  C   . LEU B 1 269 ? 68.31808  -18.45756 0.09954   1.000 44.44681  ? 269 LEU B C   1 
ATOM   4659 O  O   . LEU B 1 269 ? 67.63404  -17.56091 -0.40737  1.000 43.93708  ? 269 LEU B O   1 
ATOM   4660 C  CB  . LEU B 1 269 ? 69.91831  -19.68424 -1.40002  1.000 38.17889  ? 269 LEU B CB  1 
ATOM   4661 C  CG  . LEU B 1 269 ? 71.29516  -19.74161 -2.06504  1.000 46.29552  ? 269 LEU B CG  1 
ATOM   4662 C  CD1 . LEU B 1 269 ? 71.48288  -21.04364 -2.83096  1.000 45.44549  ? 269 LEU B CD1 1 
ATOM   4663 C  CD2 . LEU B 1 269 ? 71.46761  -18.55393 -2.99287  1.000 40.86259  ? 269 LEU B CD2 1 
ATOM   4664 N  N   . GLU B 1 270 ? 67.82322  -19.30861 1.00290   1.000 43.86091  ? 270 GLU B N   1 
ATOM   4665 C  CA  . GLU B 1 270 ? 66.47408  -19.12940 1.53077   1.000 47.83009  ? 270 GLU B CA  1 
ATOM   4666 C  C   . GLU B 1 270 ? 66.29716  -17.74393 2.13851   1.000 45.50076  ? 270 GLU B C   1 
ATOM   4667 O  O   . GLU B 1 270 ? 65.25498  -17.10468 1.95526   1.000 48.56286  ? 270 GLU B O   1 
ATOM   4668 C  CB  . GLU B 1 270 ? 66.16856  -20.19946 2.57970   1.000 47.53963  ? 270 GLU B CB  1 
ATOM   4669 C  CG  . GLU B 1 270 ? 65.58387  -21.48805 2.04064   1.000 48.16607  ? 270 GLU B CG  1 
ATOM   4670 C  CD  . GLU B 1 270 ? 65.14937  -22.42350 3.15492   1.000 47.43024  ? 270 GLU B CD  1 
ATOM   4671 O  OE1 . GLU B 1 270 ? 65.63977  -22.26195 4.29090   1.000 50.75098  ? 270 GLU B OE1 1 
ATOM   4672 O  OE2 . GLU B 1 270 ? 64.31751  -23.31732 2.90001   1.000 50.16347  ? 270 GLU B OE2 1 
ATOM   4673 N  N   . SER B 1 271 ? 67.30683  -17.26348 2.86992   1.000 41.24883  ? 271 SER B N   1 
ATOM   4674 C  CA  . SER B 1 271 ? 67.21240  -15.96041 3.51682   1.000 46.91008  ? 271 SER B CA  1 
ATOM   4675 C  C   . SER B 1 271 ? 67.17129  -14.80922 2.52037   1.000 57.04659  ? 271 SER B C   1 
ATOM   4676 O  O   . SER B 1 271 ? 66.85152  -13.68464 2.91829   1.000 54.19259  ? 271 SER B O   1 
ATOM   4677 C  CB  . SER B 1 271 ? 68.38121  -15.76356 4.48410   1.000 38.80024  ? 271 SER B CB  1 
ATOM   4678 O  OG  . SER B 1 271 ? 69.56808  -15.41837 3.79279   1.000 49.57874  ? 271 SER B OG  1 
ATOM   4679 N  N   . CYS B 1 272 ? 67.49061  -15.05645 1.24861   1.000 47.11249  ? 272 CYS B N   1 
ATOM   4680 C  CA  . CYS B 1 272 ? 67.37550  -14.04876 0.20343   1.000 41.02113  ? 272 CYS B CA  1 
ATOM   4681 C  C   . CYS B 1 272 ? 65.98697  -13.99932 -0.42021  1.000 45.20878  ? 272 CYS B C   1 
ATOM   4682 O  O   . CYS B 1 272 ? 65.69510  -13.05977 -1.16776  1.000 49.29910  ? 272 CYS B O   1 
ATOM   4683 C  CB  . CYS B 1 272 ? 68.41222  -14.30184 -0.90345  1.000 45.15356  ? 272 CYS B CB  1 
ATOM   4684 S  SG  . CYS B 1 272 ? 70.14524  -14.17189 -0.39768  1.000 55.08127  ? 272 CYS B SG  1 
ATOM   4685 N  N   . LEU B 1 273 ? 65.13039  -14.97931 -0.13363  1.000 47.18770  ? 273 LEU B N   1 
ATOM   4686 C  CA  . LEU B 1 273 ? 63.83487  -15.04432 -0.80206  1.000 48.88853  ? 273 LEU B CA  1 
ATOM   4687 C  C   . LEU B 1 273 ? 62.91060  -13.85922 -0.51846  1.000 53.16207  ? 273 LEU B C   1 
ATOM   4688 O  O   . LEU B 1 273 ? 62.13306  -13.50941 -1.42328  1.000 53.51992  ? 273 LEU B O   1 
ATOM   4689 C  CB  . LEU B 1 273 ? 63.13976  -16.36634 -0.44663  1.000 44.52694  ? 273 LEU B CB  1 
ATOM   4690 C  CG  . LEU B 1 273 ? 63.73848  -17.60691 -1.11285  1.000 50.55616  ? 273 LEU B CG  1 
ATOM   4691 C  CD1 . LEU B 1 273 ? 62.94410  -18.85205 -0.75962  1.000 50.75859  ? 273 LEU B CD1 1 
ATOM   4692 C  CD2 . LEU B 1 273 ? 63.79664  -17.41657 -2.61987  1.000 47.25296  ? 273 LEU B CD2 1 
ATOM   4693 N  N   . PRO B 1 274 ? 62.90886  -13.22888 0.66604   1.000 54.82596  ? 274 PRO B N   1 
ATOM   4694 C  CA  . PRO B 1 274 ? 62.13418  -11.97837 0.80027   1.000 51.47598  ? 274 PRO B CA  1 
ATOM   4695 C  C   . PRO B 1 274 ? 62.54333  -10.91050 -0.20221  1.000 48.99580  ? 274 PRO B C   1 
ATOM   4696 O  O   . PRO B 1 274 ? 61.68030  -10.32537 -0.86870  1.000 56.06068  ? 274 PRO B O   1 
ATOM   4697 C  CB  . PRO B 1 274 ? 62.41536  -11.55253 2.24696   1.000 50.06691  ? 274 PRO B CB  1 
ATOM   4698 C  CG  . PRO B 1 274 ? 62.67043  -12.82563 2.96064   1.000 51.74129  ? 274 PRO B CG  1 
ATOM   4699 C  CD  . PRO B 1 274 ? 63.39391  -13.70655 1.97610   1.000 48.69453  ? 274 PRO B CD  1 
ATOM   4700 N  N   . LYS B 1 275 ? 63.84547  -10.64250 -0.33245  1.000 48.53735  ? 275 LYS B N   1 
ATOM   4701 C  CA  . LYS B 1 275 ? 64.30408  -9.65833  -1.30798  1.000 54.41904  ? 275 LYS B CA  1 
ATOM   4702 C  C   . LYS B 1 275 ? 63.97734  -10.09214 -2.73251  1.000 58.29267  ? 275 LYS B C   1 
ATOM   4703 O  O   . LYS B 1 275 ? 63.68151  -9.25207  -3.59152  1.000 55.59228  ? 275 LYS B O   1 
ATOM   4704 C  CB  . LYS B 1 275 ? 65.80477  -9.42334  -1.14972  1.000 56.37857  ? 275 LYS B CB  1 
ATOM   4705 C  CG  . LYS B 1 275 ? 66.17212  -8.51503  0.01205   1.000 60.71265  ? 275 LYS B CG  1 
ATOM   4706 C  CD  . LYS B 1 275 ? 65.83390  -7.05538  -0.27378  1.000 74.56179  ? 275 LYS B CD  1 
ATOM   4707 C  CE  . LYS B 1 275 ? 66.82828  -6.40749  -1.23674  1.000 73.85202  ? 275 LYS B CE  1 
ATOM   4708 N  NZ  . LYS B 1 275 ? 66.53066  -6.68307  -2.67115  1.000 67.01381  ? 275 LYS B NZ  1 
ATOM   4709 N  N   . VAL B 1 276 ? 64.03119  -11.39917 -3.00548  1.000 50.03156  ? 276 VAL B N   1 
ATOM   4710 C  CA  . VAL B 1 276 ? 63.64492  -11.89662 -4.32469  1.000 48.16159  ? 276 VAL B CA  1 
ATOM   4711 C  C   . VAL B 1 276 ? 62.16949  -11.62105 -4.58705  1.000 50.23435  ? 276 VAL B C   1 
ATOM   4712 O  O   . VAL B 1 276 ? 61.77719  -11.26813 -5.70655  1.000 47.42464  ? 276 VAL B O   1 
ATOM   4713 C  CB  . VAL B 1 276 ? 63.97366  -13.39626 -4.44804  1.000 50.27471  ? 276 VAL B CB  1 
ATOM   4714 C  CG1 . VAL B 1 276 ? 63.32624  -13.99402 -5.68947  1.000 48.54682  ? 276 VAL B CG1 1 
ATOM   4715 C  CG2 . VAL B 1 276 ? 65.48168  -13.60513 -4.47454  1.000 45.36359  ? 276 VAL B CG2 1 
ATOM   4716 N  N   . GLY B 1 277 ? 61.32987  -11.77061 -3.55888  1.000 53.22116  ? 277 GLY B N   1 
ATOM   4717 C  CA  . GLY B 1 277 ? 59.91603  -11.46957 -3.72106  1.000 52.39507  ? 277 GLY B CA  1 
ATOM   4718 C  C   . GLY B 1 277 ? 59.66270  -10.01963 -4.09003  1.000 55.22282  ? 277 GLY B C   1 
ATOM   4719 O  O   . GLY B 1 277 ? 58.75474  -9.71590  -4.86756  1.000 58.03685  ? 277 GLY B O   1 
ATOM   4720 N  N   . GLU B 1 278 ? 60.46668  -9.10530  -3.54375  1.000 54.14252  ? 278 GLU B N   1 
ATOM   4721 C  CA  . GLU B 1 278 ? 60.32652  -7.69460  -3.89004  1.000 58.35274  ? 278 GLU B CA  1 
ATOM   4722 C  C   . GLU B 1 278 ? 60.83358  -7.41591  -5.29923  1.000 58.15682  ? 278 GLU B C   1 
ATOM   4723 O  O   . GLU B 1 278 ? 60.20083  -6.66640  -6.05279  1.000 55.28494  ? 278 GLU B O   1 
ATOM   4724 C  CB  . GLU B 1 278 ? 61.07231  -6.82981  -2.87542  1.000 60.67003  ? 278 GLU B CB  1 
ATOM   4725 C  CG  . GLU B 1 278 ? 60.60124  -7.00696  -1.44453  1.000 66.10161  ? 278 GLU B CG  1 
ATOM   4726 C  CD  . GLU B 1 278 ? 61.52679  -6.34371  -0.44412  1.000 72.89238  ? 278 GLU B CD  1 
ATOM   4727 O  OE1 . GLU B 1 278 ? 62.47700  -5.65417  -0.87370  1.000 77.91525  ? 278 GLU B OE1 1 
ATOM   4728 O  OE2 . GLU B 1 278 ? 61.30649  -6.51657  0.77191   1.000 74.29079  ? 278 GLU B OE2 1 
ATOM   4729 N  N   . ILE B 1 279 ? 61.97467  -8.00701  -5.66846  1.000 55.75301  ? 279 ILE B N   1 
ATOM   4730 C  CA  . ILE B 1 279 ? 62.54659  -7.78991  -6.99674  1.000 49.34295  ? 279 ILE B CA  1 
ATOM   4731 C  C   . ILE B 1 279 ? 61.54783  -8.16954  -8.08237  1.000 51.74538  ? 279 ILE B C   1 
ATOM   4732 O  O   . ILE B 1 279 ? 61.39305  -7.45671  -9.08162  1.000 55.09526  ? 279 ILE B O   1 
ATOM   4733 C  CB  . ILE B 1 279 ? 63.86459  -8.57417  -7.13991  1.000 52.55529  ? 279 ILE B CB  1 
ATOM   4734 C  CG1 . ILE B 1 279 ? 64.94025  -7.98246  -6.22745  1.000 49.07741  ? 279 ILE B CG1 1 
ATOM   4735 C  CG2 . ILE B 1 279 ? 64.33369  -8.58788  -8.58713  1.000 50.96371  ? 279 ILE B CG2 1 
ATOM   4736 C  CD1 . ILE B 1 279 ? 66.16872  -8.85151  -6.09099  1.000 51.75110  ? 279 ILE B CD1 1 
ATOM   4737 N  N   . TYR B 1 280 ? 60.84720  -9.28579  -7.90183  1.000 55.42855  ? 280 TYR B N   1 
ATOM   4738 C  CA  . TYR B 1 280 ? 59.86685  -9.74641  -8.87487  1.000 55.03169  ? 280 TYR B CA  1 
ATOM   4739 C  C   . TYR B 1 280 ? 58.45695  -9.24443  -8.58965  1.000 59.75342  ? 280 TYR B C   1 
ATOM   4740 O  O   . TYR B 1 280 ? 57.53355  -9.58344  -9.33840  1.000 55.02662  ? 280 TYR B O   1 
ATOM   4741 C  CB  . TYR B 1 280 ? 59.87783  -11.27560 -8.94390  1.000 56.73495  ? 280 TYR B CB  1 
ATOM   4742 C  CG  . TYR B 1 280 ? 61.08136  -11.81453 -9.67797  1.000 57.51067  ? 280 TYR B CG  1 
ATOM   4743 C  CD1 . TYR B 1 280 ? 61.11380  -11.83527 -11.06516 1.000 52.49181  ? 280 TYR B CD1 1 
ATOM   4744 C  CD2 . TYR B 1 280 ? 62.19073  -12.28583 -8.98810  1.000 52.62059  ? 280 TYR B CD2 1 
ATOM   4745 C  CE1 . TYR B 1 280 ? 62.21161  -12.31751 -11.74726 1.000 49.11327  ? 280 TYR B CE1 1 
ATOM   4746 C  CE2 . TYR B 1 280 ? 63.29598  -12.77176 -9.66227  1.000 52.72939  ? 280 TYR B CE2 1 
ATOM   4747 C  CZ  . TYR B 1 280 ? 63.29951  -12.78513 -11.04243 1.000 49.24541  ? 280 TYR B CZ  1 
ATOM   4748 O  OH  . TYR B 1 280 ? 64.39354  -13.26579 -11.72243 1.000 56.07978  ? 280 TYR B OH  1 
ATOM   4749 N  N   . GLN B 1 281 ? 58.27379  -8.44890  -7.53356  1.000 60.49089  ? 281 GLN B N   1 
ATOM   4750 C  CA  . GLN B 1 281 ? 57.00048  -7.78781  -7.24357  1.000 63.03121  ? 281 GLN B CA  1 
ATOM   4751 C  C   . GLN B 1 281 ? 55.87093  -8.80420  -7.07777  1.000 58.52843  ? 281 GLN B C   1 
ATOM   4752 O  O   . GLN B 1 281 ? 54.82196  -8.71633  -7.71902  1.000 60.51845  ? 281 GLN B O   1 
ATOM   4753 C  CB  . GLN B 1 281 ? 56.66470  -6.75741  -8.32618  1.000 58.19838  ? 281 GLN B CB  1 
ATOM   4754 C  CG  . GLN B 1 281 ? 57.74759  -5.70837  -8.53077  1.000 62.76771  ? 281 GLN B CG  1 
ATOM   4755 C  CD  . GLN B 1 281 ? 57.50008  -4.83187  -9.74559  1.000 76.62013  ? 281 GLN B CD  1 
ATOM   4756 O  OE1 . GLN B 1 281 ? 56.48184  -4.96236  -10.42479 1.000 82.61370  ? 281 GLN B OE1 1 
ATOM   4757 N  NE2 . GLN B 1 281 ? 58.43708  -3.93362  -10.02652 1.000 81.59859  ? 281 GLN B NE2 1 
ATOM   4758 N  N   . LEU B 1 282 ? 56.09808  -9.78186  -6.20592  1.000 60.01076  ? 282 LEU B N   1 
ATOM   4759 C  CA  . LEU B 1 282 ? 55.08858  -10.79705 -5.94170  1.000 64.76316  ? 282 LEU B CA  1 
ATOM   4760 C  C   . LEU B 1 282 ? 53.95994  -10.21770 -5.09769  1.000 65.93298  ? 282 LEU B C   1 
ATOM   4761 O  O   . LEU B 1 282 ? 54.19899  -9.46269  -4.15106  1.000 62.16115  ? 282 LEU B O   1 
ATOM   4762 C  CB  . LEU B 1 282 ? 55.70945  -11.99098 -5.21634  1.000 60.33460  ? 282 LEU B CB  1 
ATOM   4763 C  CG  . LEU B 1 282 ? 56.91913  -12.69403 -5.83173  1.000 60.73523  ? 282 LEU B CG  1 
ATOM   4764 C  CD1 . LEU B 1 282 ? 57.35143  -13.85703 -4.94618  1.000 52.16518  ? 282 LEU B CD1 1 
ATOM   4765 C  CD2 . LEU B 1 282 ? 56.60553  -13.17072 -7.23890  1.000 52.53301  ? 282 LEU B CD2 1 
ATOM   4766 N  N   . ASP B 1 283 ? 52.72257  -10.57681 -5.43843  1.000 63.68231  ? 283 ASP B N   1 
ATOM   4767 C  CA  . ASP B 1 283 ? 51.58390  -10.21099 -4.60509  1.000 63.68370  ? 283 ASP B CA  1 
ATOM   4768 C  C   . ASP B 1 283 ? 51.44445  -11.24250 -3.48479  1.000 64.11079  ? 283 ASP B C   1 
ATOM   4769 O  O   . ASP B 1 283 ? 52.28290  -12.13357 -3.32356  1.000 64.64546  ? 283 ASP B O   1 
ATOM   4770 C  CB  . ASP B 1 283 ? 50.31678  -10.05595 -5.45013  1.000 65.33965  ? 283 ASP B CB  1 
ATOM   4771 C  CG  . ASP B 1 283 ? 49.91076  -11.33462 -6.17158  1.000 63.77915  ? 283 ASP B CG  1 
ATOM   4772 O  OD1 . ASP B 1 283 ? 50.40337  -12.42355 -5.81876  1.000 72.04687  ? 283 ASP B OD1 1 
ATOM   4773 O  OD2 . ASP B 1 283 ? 49.08205  -11.24534 -7.10285  1.000 66.45986  ? 283 ASP B OD2 1 
ATOM   4774 N  N   . THR B 1 284 ? 50.37147  -11.13790 -2.69761  1.000 66.62693  ? 284 THR B N   1 
ATOM   4775 C  CA  . THR B 1 284 ? 50.25618  -11.96178 -1.49690  1.000 66.66189  ? 284 THR B CA  1 
ATOM   4776 C  C   . THR B 1 284 ? 50.11913  -13.44130 -1.83986  1.000 61.70116  ? 284 THR B C   1 
ATOM   4777 O  O   . THR B 1 284 ? 50.74525  -14.29145 -1.19597  1.000 61.55926  ? 284 THR B O   1 
ATOM   4778 C  CB  . THR B 1 284 ? 49.07204  -11.49492 -0.65000  1.000 67.03135  ? 284 THR B CB  1 
ATOM   4779 O  OG1 . THR B 1 284 ? 49.15823  -10.07867 -0.44912  1.000 70.08784  ? 284 THR B OG1 1 
ATOM   4780 C  CG2 . THR B 1 284 ? 49.08100  -12.19045 0.70428   1.000 61.61240  ? 284 THR B CG2 1 
ATOM   4781 N  N   . ALA B 1 285 ? 49.30897  -13.76991 -2.84914  1.000 59.17865  ? 285 ALA B N   1 
ATOM   4782 C  CA  . ALA B 1 285 ? 49.12554  -15.17076 -3.21624  1.000 60.17364  ? 285 ALA B CA  1 
ATOM   4783 C  C   . ALA B 1 285 ? 50.40554  -15.76366 -3.79122  1.000 63.24656  ? 285 ALA B C   1 
ATOM   4784 O  O   . ALA B 1 285 ? 50.72859  -16.92872 -3.53133  1.000 63.65621  ? 285 ALA B O   1 
ATOM   4785 C  CB  . ALA B 1 285 ? 47.97585  -15.30838 -4.21284  1.000 56.56444  ? 285 ALA B CB  1 
ATOM   4786 N  N   . GLU B 1 286 ? 51.14922  -14.97565 -4.57067  1.000 63.05356  ? 286 GLU B N   1 
ATOM   4787 C  CA  . GLU B 1 286 ? 52.40071  -15.46501 -5.13797  1.000 55.69817  ? 286 GLU B CA  1 
ATOM   4788 C  C   . GLU B 1 286 ? 53.44972  -15.69332 -4.05646  1.000 59.10005  ? 286 GLU B C   1 
ATOM   4789 O  O   . GLU B 1 286 ? 54.25301  -16.62767 -4.15426  1.000 60.39134  ? 286 GLU B O   1 
ATOM   4790 C  CB  . GLU B 1 286 ? 52.91085  -14.48623 -6.19521  1.000 59.33573  ? 286 GLU B CB  1 
ATOM   4791 C  CG  . GLU B 1 286 ? 52.08428  -14.48232 -7.47535  1.000 51.14312  ? 286 GLU B CG  1 
ATOM   4792 C  CD  . GLU B 1 286 ? 52.59459  -13.49061 -8.50240  1.000 57.96293  ? 286 GLU B CD  1 
ATOM   4793 O  OE1 . GLU B 1 286 ? 53.16790  -12.45662 -8.10051  1.000 61.47555  ? 286 GLU B OE1 1 
ATOM   4794 O  OE2 . GLU B 1 286 ? 52.42675  -13.74843 -9.71390  1.000 59.20861  ? 286 GLU B OE2 1 
ATOM   4795 N  N   . ARG B 1 287 ? 53.45802  -14.85449 -3.01662  1.000 61.72242  ? 287 ARG B N   1 
ATOM   4796 C  CA  . ARG B 1 287 ? 54.40534  -15.04776 -1.92271  1.000 59.03904  ? 287 ARG B CA  1 
ATOM   4797 C  C   . ARG B 1 287 ? 54.09554  -16.31736 -1.13973  1.000 57.33670  ? 287 ARG B C   1 
ATOM   4798 O  O   . ARG B 1 287 ? 55.01278  -17.03815 -0.72846  1.000 58.01964  ? 287 ARG B O   1 
ATOM   4799 C  CB  . ARG B 1 287 ? 54.40217  -13.83227 -0.99448  1.000 61.50841  ? 287 ARG B CB  1 
ATOM   4800 C  CG  . ARG B 1 287 ? 55.05111  -12.59429 -1.59016  1.000 62.00503  ? 287 ARG B CG  1 
ATOM   4801 C  CD  . ARG B 1 287 ? 55.27103  -11.52045 -0.53441  1.000 66.04283  ? 287 ARG B CD  1 
ATOM   4802 N  NE  . ARG B 1 287 ? 54.02051  -11.08097 0.07352   1.000 69.84565  ? 287 ARG B NE  1 
ATOM   4803 C  CZ  . ARG B 1 287 ? 53.27533  -10.08323 -0.38262  1.000 72.59006  ? 287 ARG B CZ  1 
ATOM   4804 N  NH1 . ARG B 1 287 ? 53.62106  -9.39925  -1.46067  1.000 74.06601  ? 287 ARG B NH1 1 
ATOM   4805 N  NH2 . ARG B 1 287 ? 52.15570  -9.76267  0.25991   1.000 70.51527  ? 287 ARG B NH2 1 
ATOM   4806 N  N   . GLU B 1 288 ? 52.81040  -16.60726 -0.92209  1.000 56.66614  ? 288 GLU B N   1 
ATOM   4807 C  CA  . GLU B 1 288 ? 52.44005  -17.83355 -0.22370  1.000 53.15069  ? 288 GLU B CA  1 
ATOM   4808 C  C   . GLU B 1 288 ? 52.77411  -19.06414 -1.05842  1.000 57.26074  ? 288 GLU B C   1 
ATOM   4809 O  O   . GLU B 1 288 ? 53.19309  -20.09382 -0.51661  1.000 59.04515  ? 288 GLU B O   1 
ATOM   4810 C  CB  . GLU B 1 288 ? 50.95353  -17.80773 0.12910   1.000 54.02600  ? 288 GLU B CB  1 
ATOM   4811 N  N   . ALA B 1 289 ? 52.59595  -18.97605 -2.37910  1.000 53.52661  ? 289 ALA B N   1 
ATOM   4812 C  CA  . ALA B 1 289 ? 52.96785  -20.08538 -3.25125  1.000 55.34154  ? 289 ALA B CA  1 
ATOM   4813 C  C   . ALA B 1 289 ? 54.47165  -20.33144 -3.21535  1.000 57.03815  ? 289 ALA B C   1 
ATOM   4814 O  O   . ALA B 1 289 ? 54.91984  -21.48402 -3.18830  1.000 56.25913  ? 289 ALA B O   1 
ATOM   4815 C  CB  . ALA B 1 289 ? 52.49766  -19.80990 -4.67972  1.000 49.85338  ? 289 ALA B CB  1 
ATOM   4816 N  N   . LEU B 1 290 ? 55.26651  -19.25769 -3.21091  1.000 49.44233  ? 290 LEU B N   1 
ATOM   4817 C  CA  . LEU B 1 290 ? 56.71239  -19.40363 -3.08054  1.000 48.71058  ? 290 LEU B CA  1 
ATOM   4818 C  C   . LEU B 1 290 ? 57.08330  -20.06413 -1.75872  1.000 57.21175  ? 290 LEU B C   1 
ATOM   4819 O  O   . LEU B 1 290 ? 58.00164  -20.89092 -1.70511  1.000 52.65307  ? 290 LEU B O   1 
ATOM   4820 C  CB  . LEU B 1 290 ? 57.38904  -18.03908 -3.20476  1.000 51.21791  ? 290 LEU B CB  1 
ATOM   4821 C  CG  . LEU B 1 290 ? 58.89757  -18.01619 -2.95004  1.000 53.06434  ? 290 LEU B CG  1 
ATOM   4822 C  CD1 . LEU B 1 290 ? 59.63219  -18.90274 -3.95541  1.000 43.60993  ? 290 LEU B CD1 1 
ATOM   4823 C  CD2 . LEU B 1 290 ? 59.43078  -16.59008 -2.98267  1.000 48.77028  ? 290 LEU B CD2 1 
ATOM   4824 N  N   . GLU B 1 291 ? 56.37752  -19.71399 -0.68040  1.000 54.14897  ? 291 GLU B N   1 
ATOM   4825 C  CA  . GLU B 1 291 ? 56.65822  -20.32286 0.61549   1.000 56.34634  ? 291 GLU B CA  1 
ATOM   4826 C  C   . GLU B 1 291 ? 56.34002  -21.81382 0.60767   1.000 56.13228  ? 291 GLU B C   1 
ATOM   4827 O  O   . GLU B 1 291 ? 57.06963  -22.61219 1.20694   1.000 56.82645  ? 291 GLU B O   1 
ATOM   4828 C  CB  . GLU B 1 291 ? 55.87026  -19.60376 1.71090   1.000 55.45335  ? 291 GLU B CB  1 
ATOM   4829 C  CG  . GLU B 1 291 ? 56.03708  -20.18956 3.10351   1.000 56.59726  ? 291 GLU B CG  1 
ATOM   4830 C  CD  . GLU B 1 291 ? 57.40548  -19.91973 3.70239   1.000 63.69629  ? 291 GLU B CD  1 
ATOM   4831 O  OE1 . GLU B 1 291 ? 58.19776  -19.17445 3.08746   1.000 64.61994  ? 291 GLU B OE1 1 
ATOM   4832 O  OE2 . GLU B 1 291 ? 57.68761  -20.45352 4.79647   1.000 67.34171  ? 291 GLU B OE2 1 
ATOM   4833 N  N   . ARG B 1 292 ? 55.25830  -22.20950 -0.06710  1.000 51.24213  ? 292 ARG B N   1 
ATOM   4834 C  CA  . ARG B 1 292 ? 54.93468  -23.62862 -0.16792  1.000 51.50980  ? 292 ARG B CA  1 
ATOM   4835 C  C   . ARG B 1 292 ? 55.98124  -24.37573 -0.98412  1.000 54.53229  ? 292 ARG B C   1 
ATOM   4836 O  O   . ARG B 1 292 ? 56.39147  -25.48242 -0.61425  1.000 49.74986  ? 292 ARG B O   1 
ATOM   4837 C  CB  . ARG B 1 292 ? 53.54881  -23.81427 -0.78388  1.000 54.68244  ? 292 ARG B CB  1 
ATOM   4838 C  CG  . ARG B 1 292 ? 52.40347  -23.33079 0.08591   1.000 58.23264  ? 292 ARG B CG  1 
ATOM   4839 C  CD  . ARG B 1 292 ? 51.16810  -24.17249 -0.16850  1.000 56.74981  ? 292 ARG B CD  1 
ATOM   4840 N  NE  . ARG B 1 292 ? 51.40375  -25.56882 0.17820   1.000 59.15586  ? 292 ARG B NE  1 
ATOM   4841 C  CZ  . ARG B 1 292 ? 50.59199  -26.56735 -0.14010  1.000 61.08860  ? 292 ARG B CZ  1 
ATOM   4842 N  NH1 . ARG B 1 292 ? 49.47570  -26.36098 -0.81970  1.000 63.28119  ? 292 ARG B NH1 1 
ATOM   4843 N  NH2 . ARG B 1 292 ? 50.91123  -27.80517 0.22668   1.000 56.89841  ? 292 ARG B NH2 1 
ATOM   4844 N  N   . TYR B 1 293 ? 56.41792  -23.78899 -2.10071  1.000 50.56441  ? 293 TYR B N   1 
ATOM   4845 C  CA  . TYR B 1 293 ? 57.46812  -24.40498 -2.90447  1.000 52.06455  ? 293 TYR B CA  1 
ATOM   4846 C  C   . TYR B 1 293 ? 58.72782  -24.63448 -2.07998  1.000 50.27736  ? 293 TYR B C   1 
ATOM   4847 O  O   . TYR B 1 293 ? 59.36564  -25.68853 -2.18437  1.000 50.00055  ? 293 TYR B O   1 
ATOM   4848 C  CB  . TYR B 1 293 ? 57.76972  -23.52375 -4.11447  1.000 46.46573  ? 293 TYR B CB  1 
ATOM   4849 C  CG  . TYR B 1 293 ? 58.55635  -24.20114 -5.21341  1.000 51.57792  ? 293 TYR B CG  1 
ATOM   4850 C  CD1 . TYR B 1 293 ? 57.99186  -25.21919 -5.97130  1.000 52.09557  ? 293 TYR B CD1 1 
ATOM   4851 C  CD2 . TYR B 1 293 ? 59.85309  -23.80308 -5.51374  1.000 46.88554  ? 293 TYR B CD2 1 
ATOM   4852 C  CE1 . TYR B 1 293 ? 58.70347  -25.83558 -6.98665  1.000 48.65864  ? 293 TYR B CE1 1 
ATOM   4853 C  CE2 . TYR B 1 293 ? 60.57116  -24.41135 -6.52771  1.000 42.63535  ? 293 TYR B CE2 1 
ATOM   4854 C  CZ  . TYR B 1 293 ? 59.99179  -25.42620 -7.26054  1.000 49.28213  ? 293 TYR B CZ  1 
ATOM   4855 O  OH  . TYR B 1 293 ? 60.70224  -26.03186 -8.27111  1.000 47.90752  ? 293 TYR B OH  1 
ATOM   4856 N  N   . ARG B 1 294 ? 59.09173  -23.66145 -1.24359  1.000 45.21686  ? 294 ARG B N   1 
ATOM   4857 C  CA  . ARG B 1 294 ? 60.29314  -23.78664 -0.42565  1.000 50.27556  ? 294 ARG B CA  1 
ATOM   4858 C  C   . ARG B 1 294 ? 60.16417  -24.92562 0.57924   1.000 50.20490  ? 294 ARG B C   1 
ATOM   4859 O  O   . ARG B 1 294 ? 61.06377  -25.76482 0.70433   1.000 48.80856  ? 294 ARG B O   1 
ATOM   4860 C  CB  . ARG B 1 294 ? 60.56991  -22.46598 0.29399   1.000 52.96999  ? 294 ARG B CB  1 
ATOM   4861 C  CG  . ARG B 1 294 ? 61.76695  -22.50957 1.22627   1.000 51.81609  ? 294 ARG B CG  1 
ATOM   4862 C  CD  . ARG B 1 294 ? 61.91818  -21.21170 2.00367   1.000 53.75307  ? 294 ARG B CD  1 
ATOM   4863 N  NE  . ARG B 1 294 ? 60.90967  -21.07166 3.04755   1.000 52.21853  ? 294 ARG B NE  1 
ATOM   4864 C  CZ  . ARG B 1 294 ? 61.06074  -21.49596 4.29495   1.000 54.91768  ? 294 ARG B CZ  1 
ATOM   4865 N  NH1 . ARG B 1 294 ? 62.16373  -22.11300 4.68620   1.000 51.09801  ? 294 ARG B NH1 1 
ATOM   4866 N  NH2 . ARG B 1 294 ? 60.08085  -21.29564 5.17211   1.000 57.12595  ? 294 ARG B NH2 1 
ATOM   4867 N  N   . THR B 1 295 ? 59.04737  -24.97385 1.30366   1.000 47.35185  ? 295 THR B N   1 
ATOM   4868 C  CA  . THR B 1 295 ? 58.89411  -25.92919 2.39365   1.000 46.89665  ? 295 THR B CA  1 
ATOM   4869 C  C   . THR B 1 295 ? 58.36393  -27.28412 1.94336   1.000 46.53738  ? 295 THR B C   1 
ATOM   4870 O  O   . THR B 1 295 ? 58.75827  -28.30887 2.51270   1.000 48.36826  ? 295 THR B O   1 
ATOM   4871 C  CB  . THR B 1 295 ? 57.96327  -25.35831 3.46834   1.000 55.67489  ? 295 THR B CB  1 
ATOM   4872 O  OG1 . THR B 1 295 ? 56.65797  -25.15941 2.91281   1.000 56.04630  ? 295 THR B OG1 1 
ATOM   4873 C  CG2 . THR B 1 295 ? 58.49505  -24.02834 3.98432   1.000 46.11697  ? 295 THR B CG2 1 
ATOM   4874 N  N   . ASP B 1 296 ? 57.48273  -27.32268 0.94246   1.000 43.33985  ? 296 ASP B N   1 
ATOM   4875 C  CA  . ASP B 1 296 ? 56.82731  -28.56403 0.54974   1.000 48.05821  ? 296 ASP B CA  1 
ATOM   4876 C  C   . ASP B 1 296 ? 57.42252  -29.20752 -0.69613  1.000 49.33493  ? 296 ASP B C   1 
ATOM   4877 O  O   . ASP B 1 296 ? 57.13448  -30.37985 -0.96033  1.000 49.58145  ? 296 ASP B O   1 
ATOM   4878 C  CB  . ASP B 1 296 ? 55.32732  -28.32628 0.32949   1.000 51.37355  ? 296 ASP B CB  1 
ATOM   4879 C  CG  . ASP B 1 296 ? 54.58516  -28.04908 1.62658   1.000 54.19726  ? 296 ASP B CG  1 
ATOM   4880 O  OD1 . ASP B 1 296 ? 55.20741  -28.15619 2.70750   1.000 53.43934  ? 296 ASP B OD1 1 
ATOM   4881 O  OD2 . ASP B 1 296 ? 53.38026  -27.72894 1.56489   1.000 57.88691  ? 296 ASP B OD2 1 
ATOM   4882 N  N   . ALA B 1 297 ? 58.23665  -28.48674 -1.46389  1.000 44.98319  ? 297 ALA B N   1 
ATOM   4883 C  CA  . ALA B 1 297 ? 58.85827  -29.04291 -2.65841  1.000 47.74769  ? 297 ALA B CA  1 
ATOM   4884 C  C   . ALA B 1 297 ? 60.37133  -29.14920 -2.54232  1.000 44.11145  ? 297 ALA B C   1 
ATOM   4885 O  O   . ALA B 1 297 ? 60.93173  -30.23113 -2.73927  1.000 44.80833  ? 297 ALA B O   1 
ATOM   4886 C  CB  . ALA B 1 297 ? 58.48221  -28.20395 -3.89038  1.000 43.79295  ? 297 ALA B CB  1 
ATOM   4887 N  N   . VAL B 1 298 ? 61.05099  -28.05454 -2.20395  1.000 45.61329  ? 298 VAL B N   1 
ATOM   4888 C  CA  . VAL B 1 298 ? 62.50995  -28.04941 -2.21973  1.000 45.60389  ? 298 VAL B CA  1 
ATOM   4889 C  C   . VAL B 1 298 ? 63.07378  -28.69181 -0.95789  1.000 44.76913  ? 298 VAL B C   1 
ATOM   4890 O  O   . VAL B 1 298 ? 63.92049  -29.58954 -1.02989  1.000 45.87342  ? 298 VAL B O   1 
ATOM   4891 C  CB  . VAL B 1 298 ? 63.03342  -26.61446 -2.40621  1.000 45.46172  ? 298 VAL B CB  1 
ATOM   4892 C  CG1 . VAL B 1 298 ? 64.55044  -26.61258 -2.45798  1.000 43.81000  ? 298 VAL B CG1 1 
ATOM   4893 C  CG2 . VAL B 1 298 ? 62.44656  -26.00041 -3.66849  1.000 43.93106  ? 298 VAL B CG2 1 
ATOM   4894 N  N   . ARG B 1 299 ? 62.62808  -28.23454 0.21547   1.000 43.11071  ? 299 ARG B N   1 
ATOM   4895 C  CA  . ARG B 1 299 ? 63.13379  -28.79213 1.46751   1.000 44.94167  ? 299 ARG B CA  1 
ATOM   4896 C  C   . ARG B 1 299 ? 62.84095  -30.28333 1.57210   1.000 47.53112  ? 299 ARG B C   1 
ATOM   4897 O  O   . ARG B 1 299 ? 63.66507  -31.05171 2.08170   1.000 47.08246  ? 299 ARG B O   1 
ATOM   4898 C  CB  . ARG B 1 299 ? 62.52731  -28.05100 2.65976   1.000 43.48511  ? 299 ARG B CB  1 
ATOM   4899 C  CG  . ARG B 1 299 ? 63.28385  -26.80395 3.07126   1.000 46.33839  ? 299 ARG B CG  1 
ATOM   4900 C  CD  . ARG B 1 299 ? 62.62309  -26.12263 4.26489   1.000 46.11594  ? 299 ARG B CD  1 
ATOM   4901 N  NE  . ARG B 1 299 ? 63.45400  -25.05262 4.80429   1.000 46.03867  ? 299 ARG B NE  1 
ATOM   4902 C  CZ  . ARG B 1 299 ? 63.83820  -24.96206 6.06989   1.000 47.57944  ? 299 ARG B CZ  1 
ATOM   4903 N  NH1 . ARG B 1 299 ? 63.43852  -25.83721 6.97755   1.000 51.25605  ? 299 ARG B NH1 1 
ATOM   4904 N  NH2 . ARG B 1 299 ? 64.63882  -23.96428 6.43451   1.000 41.74508  ? 299 ARG B NH2 1 
ATOM   4905 N  N   . THR B 1 300 ? 61.67372  -30.71247 1.08989   1.000 42.64409  ? 300 THR B N   1 
ATOM   4906 C  CA  . THR B 1 300 ? 61.28098  -32.10843 1.24574   1.000 45.48677  ? 300 THR B CA  1 
ATOM   4907 C  C   . THR B 1 300 ? 62.10806  -33.03075 0.35647   1.000 45.59776  ? 300 THR B C   1 
ATOM   4908 O  O   . THR B 1 300 ? 62.42835  -34.15589 0.75578   1.000 44.93910  ? 300 THR B O   1 
ATOM   4909 C  CB  . THR B 1 300 ? 59.79124  -32.26548 0.94993   1.000 44.07222  ? 300 THR B CB  1 
ATOM   4910 O  OG1 . THR B 1 300 ? 59.47772  -31.60590 -0.28285  1.000 47.42039  ? 300 THR B OG1 1 
ATOM   4911 C  CG2 . THR B 1 300 ? 58.96380  -31.65128 2.07014   1.000 40.60905  ? 300 THR B CG2 1 
ATOM   4912 N  N   . VAL B 1 301 ? 62.46489  -32.58129 -0.85032  1.000 43.01420  ? 301 VAL B N   1 
ATOM   4913 C  CA  . VAL B 1 301 ? 63.25172  -33.44494 -1.72539  1.000 44.37455  ? 301 VAL B CA  1 
ATOM   4914 C  C   . VAL B 1 301 ? 64.66913  -33.60474 -1.18658  1.000 46.64022  ? 301 VAL B C   1 
ATOM   4915 O  O   . VAL B 1 301 ? 65.31724  -34.63289 -1.42059  1.000 47.20805  ? 301 VAL B O   1 
ATOM   4916 C  CB  . VAL B 1 301 ? 63.24272  -32.91380 -3.17301  1.000 42.06527  ? 301 VAL B CB  1 
ATOM   4917 C  CG1 . VAL B 1 301 ? 64.22171  -31.76674 -3.34205  1.000 40.65685  ? 301 VAL B CG1 1 
ATOM   4918 C  CG2 . VAL B 1 301 ? 63.56038  -34.03413 -4.15108  1.000 40.76950  ? 301 VAL B CG2 1 
ATOM   4919 N  N   . ILE B 1 302 ? 65.16885  -32.61224 -0.44796  1.000 45.14359  ? 302 ILE B N   1 
ATOM   4920 C  CA  . ILE B 1 302 ? 66.47724  -32.74181 0.18758   1.000 45.95771  ? 302 ILE B CA  1 
ATOM   4921 C  C   . ILE B 1 302 ? 66.38994  -33.68088 1.38304   1.000 43.67877  ? 302 ILE B C   1 
ATOM   4922 O  O   . ILE B 1 302 ? 67.08808  -34.69895 1.45069   1.000 46.81095  ? 302 ILE B O   1 
ATOM   4923 C  CB  . ILE B 1 302 ? 67.01847  -31.36302 0.60591   1.000 45.63317  ? 302 ILE B CB  1 
ATOM   4924 C  CG1 . ILE B 1 302 ? 67.20157  -30.45803 -0.61241  1.000 45.29002  ? 302 ILE B CG1 1 
ATOM   4925 C  CG2 . ILE B 1 302 ? 68.33455  -31.51205 1.35361   1.000 38.22860  ? 302 ILE B CG2 1 
ATOM   4926 C  CD1 . ILE B 1 302 ? 67.73434  -29.08408 -0.26911  1.000 45.61336  ? 302 ILE B CD1 1 
ATOM   4927 N  N   . ARG B 1 303 ? 65.51288  -33.35483 2.33557   1.000 44.56447  ? 303 ARG B N   1 
ATOM   4928 C  CA  . ARG B 1 303 ? 65.45822  -34.08908 3.59592   1.000 49.25830  ? 303 ARG B CA  1 
ATOM   4929 C  C   . ARG B 1 303 ? 64.89958  -35.49558 3.40941   1.000 48.61359  ? 303 ARG B C   1 
ATOM   4930 O  O   . ARG B 1 303 ? 65.40048  -36.45020 4.01573   1.000 43.36070  ? 303 ARG B O   1 
ATOM   4931 C  CB  . ARG B 1 303 ? 64.61896  -33.31212 4.60978   1.000 43.14314  ? 303 ARG B CB  1 
ATOM   4932 C  CG  . ARG B 1 303 ? 64.32152  -34.07979 5.87979   1.000 46.35259  ? 303 ARG B CG  1 
ATOM   4933 C  CD  . ARG B 1 303 ? 65.55034  -34.18500 6.77163   1.000 49.45852  ? 303 ARG B CD  1 
ATOM   4934 N  NE  . ARG B 1 303 ? 65.37506  -35.19459 7.80917   1.000 56.38907  ? 303 ARG B NE  1 
ATOM   4935 C  CZ  . ARG B 1 303 ? 66.11539  -35.28146 8.90664   1.000 57.03437  ? 303 ARG B CZ  1 
ATOM   4936 N  NH1 . ARG B 1 303 ? 67.07008  -34.40217 9.16996   1.000 57.15350  ? 303 ARG B NH1 1 
ATOM   4937 N  NH2 . ARG B 1 303 ? 65.89201  -36.27457 9.76272   1.000 53.65887  ? 303 ARG B NH2 1 
ATOM   4938 N  N   . GLY B 1 304 ? 63.85747  -35.64233 2.58601   1.000 45.99900  ? 304 GLY B N   1 
ATOM   4939 C  CA  . GLY B 1 304 ? 63.22719  -36.94489 2.42856   1.000 45.67666  ? 304 GLY B CA  1 
ATOM   4940 C  C   . GLY B 1 304 ? 64.16095  -37.98743 1.84332   1.000 46.20537  ? 304 GLY B C   1 
ATOM   4941 O  O   . GLY B 1 304 ? 64.11743  -39.15934 2.22331   1.000 45.96204  ? 304 GLY B O   1 
ATOM   4942 N  N   . SER B 1 305 ? 65.01593  -37.57671 0.90887   1.000 45.63081  ? 305 SER B N   1 
ATOM   4943 C  CA  . SER B 1 305 ? 65.99531  -38.49981 0.34988   1.000 49.74794  ? 305 SER B CA  1 
ATOM   4944 C  C   . SER B 1 305 ? 66.99390  -38.94756 1.40673   1.000 51.81191  ? 305 SER B C   1 
ATOM   4945 O  O   . SER B 1 305 ? 67.39904  -40.11589 1.43330   1.000 50.24763  ? 305 SER B O   1 
ATOM   4946 C  CB  . SER B 1 305 ? 66.71733  -37.83938 -0.81966  1.000 49.97309  ? 305 SER B CB  1 
ATOM   4947 O  OG  . SER B 1 305 ? 67.84059  -38.60081 -1.21630  1.000 56.89810  ? 305 SER B OG  1 
ATOM   4948 N  N   . TYR B 1 306 ? 67.40312  -38.02886 2.28340   1.000 50.69215  ? 306 TYR B N   1 
ATOM   4949 C  CA  . TYR B 1 306 ? 68.35306  -38.37414 3.33331   1.000 45.48775  ? 306 TYR B CA  1 
ATOM   4950 C  C   . TYR B 1 306 ? 67.76069  -39.40074 4.28896   1.000 48.82036  ? 306 TYR B C   1 
ATOM   4951 O  O   . TYR B 1 306 ? 68.41936  -40.38243 4.64973   1.000 47.44550  ? 306 TYR B O   1 
ATOM   4952 C  CB  . TYR B 1 306 ? 68.77668  -37.11167 4.08215   1.000 47.84164  ? 306 TYR B CB  1 
ATOM   4953 C  CG  . TYR B 1 306 ? 69.53603  -37.37486 5.35884   1.000 49.43410  ? 306 TYR B CG  1 
ATOM   4954 C  CD1 . TYR B 1 306 ? 70.83430  -37.86433 5.32871   1.000 51.44473  ? 306 TYR B CD1 1 
ATOM   4955 C  CD2 . TYR B 1 306 ? 68.95741  -37.12486 6.59548   1.000 52.75184  ? 306 TYR B CD2 1 
ATOM   4956 C  CE1 . TYR B 1 306 ? 71.53445  -38.10187 6.49361   1.000 54.70416  ? 306 TYR B CE1 1 
ATOM   4957 C  CE2 . TYR B 1 306 ? 69.65028  -37.35929 7.76859   1.000 57.55265  ? 306 TYR B CE2 1 
ATOM   4958 C  CZ  . TYR B 1 306 ? 70.93821  -37.84797 7.71070   1.000 57.98943  ? 306 TYR B CZ  1 
ATOM   4959 O  OH  . TYR B 1 306 ? 71.63362  -38.08481 8.87269   1.000 62.41375  ? 306 TYR B OH  1 
ATOM   4960 N  N   . ASP B 1 307 ? 66.50956  -39.19224 4.70555   1.000 45.09900  ? 307 ASP B N   1 
ATOM   4961 C  CA  . ASP B 1 307 ? 65.86722  -40.13690 5.61386   1.000 52.86653  ? 307 ASP B CA  1 
ATOM   4962 C  C   . ASP B 1 307 ? 65.67186  -41.49517 4.95315   1.000 54.61550  ? 307 ASP B C   1 
ATOM   4963 O  O   . ASP B 1 307 ? 65.88985  -42.53631 5.58368   1.000 58.43739  ? 307 ASP B O   1 
ATOM   4964 C  CB  . ASP B 1 307 ? 64.52606  -39.57942 6.09139   1.000 50.83485  ? 307 ASP B CB  1 
ATOM   4965 C  CG  . ASP B 1 307 ? 64.68438  -38.40985 7.04309   1.000 50.57935  ? 307 ASP B CG  1 
ATOM   4966 O  OD1 . ASP B 1 307 ? 65.64535  -38.41712 7.84057   1.000 58.80158  ? 307 ASP B OD1 1 
ATOM   4967 O  OD2 . ASP B 1 307 ? 63.84651  -37.48472 6.99741   1.000 50.97391  ? 307 ASP B OD2 1 
ATOM   4968 N  N   . TRP B 1 308 ? 65.26438  -41.50344 3.68287   1.000 55.51299  ? 308 TRP B N   1 
ATOM   4969 C  CA  . TRP B 1 308 ? 65.00707  -42.76254 2.99163   1.000 54.18201  ? 308 TRP B CA  1 
ATOM   4970 C  C   . TRP B 1 308 ? 66.29103  -43.55853 2.78904   1.000 58.53425  ? 308 TRP B C   1 
ATOM   4971 O  O   . TRP B 1 308 ? 66.29087  -44.78848 2.91476   1.000 64.81877  ? 308 TRP B O   1 
ATOM   4972 C  CB  . TRP B 1 308 ? 64.31802  -42.47874 1.65902   1.000 52.93486  ? 308 TRP B CB  1 
ATOM   4973 C  CG  . TRP B 1 308 ? 64.09863  -43.67580 0.78932   1.000 53.31317  ? 308 TRP B CG  1 
ATOM   4974 C  CD1 . TRP B 1 308 ? 63.16384  -44.65388 0.96098   1.000 50.29462  ? 308 TRP B CD1 1 
ATOM   4975 C  CD2 . TRP B 1 308 ? 64.80744  -44.00347 -0.41367  1.000 52.13732  ? 308 TRP B CD2 1 
ATOM   4976 N  NE1 . TRP B 1 308 ? 63.25619  -45.57934 -0.05103  1.000 47.07230  ? 308 TRP B NE1 1 
ATOM   4977 C  CE2 . TRP B 1 308 ? 64.25612  -45.20212 -0.90899  1.000 51.63565  ? 308 TRP B CE2 1 
ATOM   4978 C  CE3 . TRP B 1 308 ? 65.85909  -43.40231 -1.11644  1.000 42.67820  ? 308 TRP B CE3 1 
ATOM   4979 C  CZ2 . TRP B 1 308 ? 64.72043  -45.81221 -2.07352  1.000 46.64087  ? 308 TRP B CZ2 1 
ATOM   4980 C  CZ3 . TRP B 1 308 ? 66.31964  -44.01027 -2.27197  1.000 48.29637  ? 308 TRP B CZ3 1 
ATOM   4981 C  CH2 . TRP B 1 308 ? 65.74975  -45.20189 -2.73901  1.000 51.53990  ? 308 TRP B CH2 1 
ATOM   4982 N  N   . HIS B 1 309 ? 67.39759  -42.87629 2.48314   1.000 59.75828  ? 309 HIS B N   1 
ATOM   4983 C  CA  . HIS B 1 309 ? 68.67564  -43.56927 2.35590   1.000 61.23314  ? 309 HIS B CA  1 
ATOM   4984 C  C   . HIS B 1 309 ? 69.16290  -44.10746 3.69535   1.000 62.52742  ? 309 HIS B C   1 
ATOM   4985 O  O   . HIS B 1 309 ? 69.79527  -45.16834 3.74004   1.000 69.99710  ? 309 HIS B O   1 
ATOM   4986 C  CB  . HIS B 1 309 ? 69.73025  -42.63961 1.75300   1.000 56.32036  ? 309 HIS B CB  1 
ATOM   4987 C  CG  . HIS B 1 309 ? 69.62308  -42.47864 0.26911   1.000 52.97780  ? 309 HIS B CG  1 
ATOM   4988 N  ND1 . HIS B 1 309 ? 69.10953  -41.34461 -0.32273  1.000 60.08840  ? 309 HIS B ND1 1 
ATOM   4989 C  CD2 . HIS B 1 309 ? 69.96951  -43.30715 -0.74427  1.000 53.18900  ? 309 HIS B CD2 1 
ATOM   4990 C  CE1 . HIS B 1 309 ? 69.14464  -41.48127 -1.63664  1.000 54.32577  ? 309 HIS B CE1 1 
ATOM   4991 N  NE2 . HIS B 1 309 ? 69.66256  -42.66327 -1.91855  1.000 55.41071  ? 309 HIS B NE2 1 
ATOM   4992 N  N   . ARG B 1 310 ? 68.88489  -43.39674 4.79155   1.000 68.49108  ? 310 ARG B N   1 
ATOM   4993 C  CA  . ARG B 1 310 ? 69.35546  -43.84234 6.09994   1.000 72.23327  ? 310 ARG B CA  1 
ATOM   4994 C  C   . ARG B 1 310 ? 68.59394  -45.06528 6.59509   1.000 76.11994  ? 310 ARG B C   1 
ATOM   4995 O  O   . ARG B 1 310 ? 69.17042  -45.90905 7.29033   1.000 78.85664  ? 310 ARG B O   1 
ATOM   4996 C  CB  . ARG B 1 310 ? 69.24315  -42.70847 7.11829   1.000 69.91484  ? 310 ARG B CB  1 
ATOM   4997 C  CG  . ARG B 1 310 ? 70.27680  -41.60856 6.94703   1.000 69.24635  ? 310 ARG B CG  1 
ATOM   4998 C  CD  . ARG B 1 310 ? 71.17064  -41.49222 8.17510   1.000 79.94537  ? 310 ARG B CD  1 
ATOM   4999 N  NE  . ARG B 1 310 ? 72.19236  -42.53207 8.21697   1.000 84.06200  ? 310 ARG B NE  1 
ATOM   5000 C  CZ  . ARG B 1 310 ? 73.09025  -42.66211 9.18475   1.000 85.66428  ? 310 ARG B CZ  1 
ATOM   5001 N  NH1 . ARG B 1 310 ? 73.11403  -41.84041 10.22167  1.000 85.54512  ? 310 ARG B NH1 1 
ATOM   5002 N  NH2 . ARG B 1 310 ? 73.98657  -43.64195 9.11118   1.000 89.87053  ? 310 ARG B NH2 1 
ATOM   5003 N  N   . SER B 1 311 ? 67.31100  -45.17652 6.26537   1.000 78.63823  ? 311 SER B N   1 
ATOM   5004 C  CA  . SER B 1 311 ? 66.52068  -46.33488 6.67017   1.000 75.44915  ? 311 SER B CA  1 
ATOM   5005 C  C   . SER B 1 311 ? 66.93266  -47.57093 5.87773   1.000 74.33921  ? 311 SER B C   1 
ATOM   5006 O  O   . SER B 1 311 ? 67.47277  -47.46157 4.77670   1.000 73.62110  ? 311 SER B O   1 
ATOM   5007 C  CB  . SER B 1 311 ? 65.02635  -46.06262 6.48431   1.000 68.08657  ? 311 SER B CB  1 
ATOM   5008 O  OG  . SER B 1 311 ? 64.72357  -45.79564 5.12569   1.000 73.77525  ? 311 SER B OG  1 
HETATM 5009 C  C1  . FPF C 2 .   ? 78.67307  -13.11214 -30.13399 1.000 72.02771  ? 401 FPF A C1  1 
HETATM 5010 O  O1  . FPF C 2 .   ? 77.53641  -13.88693 -30.38365 1.000 73.78976  ? 401 FPF A O1  1 
HETATM 5011 C  C2  . FPF C 2 .   ? 79.92694  -13.98057 -30.22490 1.000 75.65855  ? 401 FPF A C2  1 
HETATM 5012 F  F   . FPF C 2 .   ? 80.44712  -14.28811 -31.44316 1.000 79.45475  ? 401 FPF A F   1 
HETATM 5013 C  C3  . FPF C 2 .   ? 80.51744  -14.43097 -29.14174 1.000 68.94144  ? 401 FPF A C3  1 
HETATM 5014 C  C4  . FPF C 2 .   ? 79.90831  -14.06923 -27.78812 1.000 67.76296  ? 401 FPF A C4  1 
HETATM 5015 C  C5  . FPF C 2 .   ? 81.77310  -15.29581 -29.30604 1.000 66.09820  ? 401 FPF A C5  1 
HETATM 5016 C  C6  . FPF C 2 .   ? 82.51156  -15.56675 -27.99734 1.000 66.78604  ? 401 FPF A C6  1 
HETATM 5017 C  C7  . FPF C 2 .   ? 83.15051  -14.27173 -27.51621 1.000 65.77812  ? 401 FPF A C7  1 
HETATM 5018 C  C8  . FPF C 2 .   ? 84.15792  -14.21865 -26.67876 1.000 58.87581  ? 401 FPF A C8  1 
HETATM 5019 C  C10 . FPF C 2 .   ? 84.82485  -15.48061 -26.13628 1.000 47.46929  ? 401 FPF A C10 1 
HETATM 5020 C  C9  . FPF C 2 .   ? 84.66149  -12.83366 -26.28592 1.000 52.99881  ? 401 FPF A C9  1 
HETATM 5021 C  C11 . FPF C 2 .   ? 84.09608  -12.40245 -24.93040 1.000 59.39684  ? 401 FPF A C11 1 
HETATM 5022 C  C12 . FPF C 2 .   ? 82.58107  -12.60006 -24.81110 1.000 56.95615  ? 401 FPF A C12 1 
HETATM 5023 C  C13 . FPF C 2 .   ? 81.72174  -11.62889 -25.06025 1.000 57.74577  ? 401 FPF A C13 1 
HETATM 5024 C  C14 . FPF C 2 .   ? 82.20013  -10.24480 -25.48956 1.000 58.53689  ? 401 FPF A C14 1 
HETATM 5025 C  C15 . FPF C 2 .   ? 80.22109  -11.88558 -24.91659 1.000 51.49660  ? 401 FPF A C15 1 
HETATM 5026 P  P1  . FPF C 2 .   ? 76.84499  -13.86776 -31.87928 1.000 63.49255  ? 401 FPF A P1  1 
HETATM 5027 O  O1A . FPF C 2 .   ? 75.49518  -14.54610 -31.80377 1.000 68.40588  ? 401 FPF A O1A 1 
HETATM 5028 O  O2A . FPF C 2 .   ? 77.72479  -14.61783 -32.85106 1.000 62.78756  ? 401 FPF A O2A 1 
HETATM 5029 O  O3A . FPF C 2 .   ? 76.64079  -12.30705 -32.37649 1.000 69.48023  ? 401 FPF A O3A 1 
HETATM 5030 P  P2  . FPF C 2 .   ? 77.75398  -11.41159 -33.20424 1.000 67.47052  ? 401 FPF A P2  1 
HETATM 5031 O  O1B . FPF C 2 .   ? 77.04172  -10.40481 -34.07893 1.000 73.30595  ? 401 FPF A O1B 1 
HETATM 5032 O  O2B . FPF C 2 .   ? 78.59353  -12.30043 -34.09009 1.000 70.37940  ? 401 FPF A O2B 1 
HETATM 5033 O  O3B . FPF C 2 .   ? 78.64717  -10.68565 -32.22437 1.000 63.72119  ? 401 FPF A O3B 1 
HETATM 5034 MG MG  . MG  D 3 .   ? 78.69777  -14.34545 -35.17687 1.000 70.66015  ? 402 MG  A MG  1 
HETATM 5035 MG MG  . MG  E 3 .   ? 74.15825  -12.45641 -31.32220 1.000 61.71601  ? 403 MG  A MG  1 
HETATM 5036 MG MG  . MG  F 3 .   ? 78.17262  -17.29829 -33.85406 1.000 75.89325  ? 404 MG  A MG  1 
HETATM 5037 O  O   . HOH G 4 .   ? 60.19475  -2.27854  -25.81563 1.000 77.24060  ? 501 HOH A O   1 
HETATM 5038 O  O   . HOH G 4 .   ? 91.56132  1.33947   -26.45829 1.000 59.21127  ? 502 HOH A O   1 
HETATM 5039 O  O   . HOH G 4 .   ? 104.97321 -17.53183 -22.21442 1.000 71.82153  ? 503 HOH A O   1 
HETATM 5040 O  O   . HOH G 4 .   ? 73.35548  -13.93122 -27.49993 1.000 59.28243  ? 504 HOH A O   1 
HETATM 5041 O  O   . HOH G 4 .   ? 75.35019  -21.28961 -36.23890 1.000 60.44775  ? 505 HOH A O   1 
HETATM 5042 O  O   . HOH G 4 .   ? 67.63230  -23.78260 -40.87894 1.000 70.61457  ? 506 HOH A O   1 
HETATM 5043 O  O   . HOH G 4 .   ? 64.56019  -14.18010 -37.94674 1.000 72.71972  ? 507 HOH A O   1 
HETATM 5044 O  O   . HOH G 4 .   ? 97.83631  -4.40464  -40.78130 1.000 58.66077  ? 508 HOH A O   1 
HETATM 5045 O  O   . HOH G 4 .   ? 92.95613  -12.08901 -43.17089 1.000 46.61258  ? 509 HOH A O   1 
HETATM 5046 O  O   . HOH G 4 .   ? 100.46755 -21.78292 -32.09701 1.000 47.08138  ? 510 HOH A O   1 
HETATM 5047 O  O   . HOH G 4 .   ? 96.41539  -31.17873 -40.17787 1.000 66.77940  ? 511 HOH A O   1 
HETATM 5048 O  O   . HOH G 4 .   ? 74.78905  -22.61310 -12.37193 1.000 53.92543  ? 512 HOH A O   1 
HETATM 5049 O  O   . HOH G 4 .   ? 96.88709  3.67091   -22.09600 1.000 47.67573  ? 513 HOH A O   1 
HETATM 5050 O  O   . HOH G 4 .   ? 94.40545  -30.36696 -38.03323 1.000 56.36924  ? 514 HOH A O   1 
HETATM 5051 O  O   . HOH G 4 .   ? 70.95756  -16.17749 -14.43489 1.000 50.50315  ? 515 HOH A O   1 
HETATM 5052 O  O   . HOH G 4 .   ? 92.43025  -34.24300 -29.36271 1.000 62.28592  ? 516 HOH A O   1 
HETATM 5053 O  O   . HOH G 4 .   ? 78.65791  -27.15760 -24.79775 1.000 49.17979  ? 517 HOH A O   1 
HETATM 5054 O  O   . HOH G 4 .   ? 89.83399  -4.84867  -7.97934  1.000 50.71982  ? 518 HOH A O   1 
HETATM 5055 O  O   . HOH G 4 .   ? 89.86396  -4.17142  -32.63244 1.000 35.91576  ? 519 HOH A O   1 
HETATM 5056 O  O   . HOH G 4 .   ? 96.33584  3.78878   -29.09029 1.000 49.82008  ? 520 HOH A O   1 
HETATM 5057 O  O   . HOH G 4 .   ? 98.51370  -2.79992  -34.25496 1.000 37.36119  ? 521 HOH A O   1 
HETATM 5058 O  O   . HOH G 4 .   ? 103.26954 -9.20974  -36.77593 1.000 50.86877  ? 522 HOH A O   1 
HETATM 5059 O  O   . HOH G 4 .   ? 90.22158  -27.60282 -41.62418 1.000 64.76637  ? 523 HOH A O   1 
HETATM 5060 O  O   . HOH G 4 .   ? 92.72377  -4.94815  -9.19806  1.000 50.71284  ? 524 HOH A O   1 
HETATM 5061 O  O   . HOH G 4 .   ? 100.56494 -10.45259 -28.27767 1.000 46.05628  ? 525 HOH A O   1 
HETATM 5062 O  O   . HOH G 4 .   ? 103.03635 -1.83097  -20.63011 1.000 59.85816  ? 526 HOH A O   1 
HETATM 5063 O  O   . HOH G 4 .   ? 87.35906  -18.45874 -13.60895 1.000 40.29093  ? 527 HOH A O   1 
HETATM 5064 O  O   . HOH G 4 .   ? 85.09242  -27.96113 -15.49145 1.000 51.67952  ? 528 HOH A O   1 
HETATM 5065 O  O   . HOH G 4 .   ? 74.05962  -21.89988 -15.66935 1.000 57.31134  ? 529 HOH A O   1 
HETATM 5066 O  O   . HOH G 4 .   ? 103.15735 -5.68195  -23.65304 1.000 51.60583  ? 530 HOH A O   1 
HETATM 5067 O  O   . HOH G 4 .   ? 90.26796  -1.09927  -32.35749 1.000 45.57891  ? 531 HOH A O   1 
HETATM 5068 O  O   . HOH G 4 .   ? 99.84427  -7.77666  -30.97860 1.000 42.97642  ? 532 HOH A O   1 
HETATM 5069 O  O   . HOH G 4 .   ? 80.84315  -22.63665 -10.74633 1.000 45.59632  ? 533 HOH A O   1 
HETATM 5070 O  O   . HOH G 4 .   ? 81.15980  -19.93893 -42.36643 1.000 58.96082  ? 534 HOH A O   1 
HETATM 5071 O  O   . HOH G 4 .   ? 74.06869  -22.56141 -8.08779  1.000 40.14765  ? 535 HOH A O   1 
HETATM 5072 O  O   . HOH G 4 .   ? 101.82935 -12.57306 -19.58105 1.000 43.56549  ? 536 HOH A O   1 
HETATM 5073 O  O   . HOH G 4 .   ? 79.83595  -13.66667 -36.76490 1.000 57.85474  ? 537 HOH A O   1 
HETATM 5074 O  O   . HOH G 4 .   ? 75.04855  -17.11498 -31.25707 1.000 64.88921  ? 538 HOH A O   1 
HETATM 5075 O  O   . HOH G 4 .   ? 84.12284  -2.80183  -14.09206 1.000 48.02652  ? 539 HOH A O   1 
HETATM 5076 O  O   . HOH G 4 .   ? 90.32353  -28.61274 -11.60538 1.000 57.66463  ? 540 HOH A O   1 
HETATM 5077 O  O   . HOH G 4 .   ? 89.00657  -9.12117  -40.00069 1.000 36.60471  ? 541 HOH A O   1 
HETATM 5078 O  O   . HOH G 4 .   ? 84.70862  -30.34353 -30.98215 1.000 51.29096  ? 542 HOH A O   1 
HETATM 5079 O  O   . HOH G 4 .   ? 90.66161  -30.63493 -18.91418 1.000 45.65548  ? 543 HOH A O   1 
HETATM 5080 O  O   . HOH G 4 .   ? 98.55421  -8.25626  -28.60684 1.000 40.22566  ? 544 HOH A O   1 
HETATM 5081 O  O   . HOH G 4 .   ? 88.24165  5.36664   -20.56625 1.000 43.28965  ? 545 HOH A O   1 
HETATM 5082 O  O   . HOH G 4 .   ? 84.74831  -9.63121  -39.98778 1.000 62.83310  ? 546 HOH A O   1 
HETATM 5083 O  O   . HOH G 4 .   ? 72.04105  -14.25069 -31.16986 1.000 61.98840  ? 547 HOH A O   1 
HETATM 5084 O  O   . HOH G 4 .   ? 98.95436  -27.05613 -28.83976 1.000 50.45731  ? 548 HOH A O   1 
HETATM 5085 O  O   . HOH G 4 .   ? 102.78648 -15.21835 -28.95552 1.000 55.88843  ? 549 HOH A O   1 
HETATM 5086 O  O   . HOH G 4 .   ? 95.25724  -9.20520  -30.94033 1.000 36.45313  ? 550 HOH A O   1 
HETATM 5087 O  O   . HOH G 4 .   ? 86.72029  -34.12274 -36.68282 1.000 66.53462  ? 551 HOH A O   1 
HETATM 5088 O  O   . HOH G 4 .   ? 86.60531  -17.44800 -49.64779 1.000 49.71666  ? 552 HOH A O   1 
HETATM 5089 O  O   . HOH G 4 .   ? 81.61639  -20.50665 -22.79786 1.000 44.33187  ? 553 HOH A O   1 
HETATM 5090 O  O   . HOH G 4 .   ? 99.14381  2.58809   -22.82740 1.000 45.12410  ? 554 HOH A O   1 
HETATM 5091 O  O   . HOH G 4 .   ? 88.68779  -32.52087 -37.57942 1.000 55.96647  ? 555 HOH A O   1 
HETATM 5092 O  O   . HOH G 4 .   ? 101.30908 -23.63469 -21.07578 1.000 49.79698  ? 556 HOH A O   1 
HETATM 5093 O  O   . HOH G 4 .   ? 100.77988 -24.54136 -33.07937 1.000 45.49753  ? 557 HOH A O   1 
HETATM 5094 O  O   . HOH G 4 .   ? 92.71283  -19.13432 -22.82602 1.000 37.19297  ? 558 HOH A O   1 
HETATM 5095 O  O   . HOH G 4 .   ? 90.25373  -31.46383 -26.44221 1.000 62.93967  ? 559 HOH A O   1 
HETATM 5096 O  O   . HOH G 4 .   ? 98.92513  -24.91316 -26.92126 1.000 48.18892  ? 560 HOH A O   1 
HETATM 5097 O  O   . HOH G 4 .   ? 82.56263  -26.70319 -3.50882  1.000 45.62310  ? 561 HOH A O   1 
HETATM 5098 O  O   . HOH G 4 .   ? 77.56405  -6.14585  -3.24502  1.000 50.53054  ? 562 HOH A O   1 
HETATM 5099 O  O   . HOH G 4 .   ? 82.72594  -22.47825 -21.35165 1.000 38.83436  ? 563 HOH A O   1 
HETATM 5100 O  O   . HOH G 4 .   ? 80.94616  -9.22660  -1.26033  1.000 55.94952  ? 564 HOH A O   1 
HETATM 5101 O  O   . HOH G 4 .   ? 89.98352  -32.54038 -30.77028 1.000 54.19755  ? 565 HOH A O   1 
HETATM 5102 O  O   . HOH G 4 .   ? 88.52022  -22.00252 -14.82162 1.000 38.94081  ? 566 HOH A O   1 
HETATM 5103 O  O   . HOH G 4 .   ? 84.16612  -0.97310  -18.21864 1.000 53.05788  ? 567 HOH A O   1 
HETATM 5104 O  O   . HOH G 4 .   ? 88.22696  -9.31130  -37.39799 1.000 38.80527  ? 568 HOH A O   1 
HETATM 5105 O  O   . HOH G 4 .   ? 98.72928  -28.18275 -25.13582 1.000 59.65909  ? 569 HOH A O   1 
HETATM 5106 O  O   . HOH G 4 .   ? 101.08805 -11.82989 -23.97080 1.000 42.17088  ? 570 HOH A O   1 
HETATM 5107 O  O   . HOH G 4 .   ? 86.04923  -7.52474  -37.00886 1.000 45.31435  ? 571 HOH A O   1 
HETATM 5108 O  O   . HOH G 4 .   ? 72.53955  -16.81426 -30.72453 1.000 60.46609  ? 572 HOH A O   1 
HETATM 5109 O  O   . HOH G 4 .   ? 85.27773  -27.13439 -41.54569 1.000 52.93271  ? 573 HOH A O   1 
HETATM 5110 O  O   . HOH G 4 .   ? 79.67439  -31.34356 -45.91688 1.000 64.29181  ? 574 HOH A O   1 
HETATM 5111 O  O   . HOH G 4 .   ? 89.36697  2.48245   -26.02634 1.000 59.44337  ? 575 HOH A O   1 
HETATM 5112 O  O   . HOH G 4 .   ? 82.19043  -3.85924  -4.79816  1.000 56.05303  ? 576 HOH A O   1 
HETATM 5113 O  O   . HOH G 4 .   ? 90.66484  -20.61943 -9.68855  1.000 38.82935  ? 577 HOH A O   1 
HETATM 5114 O  O   . HOH G 4 .   ? 84.35037  -17.94354 -43.90580 1.000 58.77696  ? 578 HOH A O   1 
HETATM 5115 O  O   . HOH G 4 .   ? 77.89152  -12.85969 4.06455   1.000 45.53335  ? 579 HOH A O   1 
HETATM 5116 O  O   . HOH G 4 .   ? 90.45465  -18.84888 -21.00352 1.000 34.15601  ? 580 HOH A O   1 
HETATM 5117 O  O   . HOH G 4 .   ? 88.98295  -21.26226 -20.36395 1.000 34.93339  ? 581 HOH A O   1 
HETATM 5118 O  O   . HOH G 4 .   ? 89.35919  4.97334   -23.98050 1.000 54.68619  ? 582 HOH A O   1 
HETATM 5119 O  O   . HOH G 4 .   ? 87.925    3.029     -38.257   1.000 50.25065  ? 583 HOH A O   1 
HETATM 5120 O  O   . HOH G 4 .   ? 83.90420  -30.10804 -19.88071 1.000 61.72327  ? 584 HOH A O   1 
HETATM 5121 O  O   . HOH G 4 .   ? 80.33792  -21.30039 -15.89952 1.000 60.58668  ? 585 HOH A O   1 
HETATM 5122 O  O   . HOH G 4 .   ? 84.82108  -4.04591  -10.91213 1.000 41.98596  ? 586 HOH A O   1 
HETATM 5123 O  O   . HOH G 4 .   ? 93.30065  -21.65828 -2.48104  1.000 49.16393  ? 587 HOH A O   1 
HETATM 5124 O  O   . HOH G 4 .   ? 78.81552  -17.14864 -36.26265 1.000 60.73459  ? 588 HOH A O   1 
HETATM 5125 O  O   . HOH G 4 .   ? 84.48115  -11.07289 -1.12991  1.000 56.27910  ? 589 HOH A O   1 
HETATM 5126 O  O   . HOH G 4 .   ? 96.24828  -16.59054 4.54854   1.000 56.32191  ? 590 HOH A O   1 
HETATM 5127 O  O   . HOH G 4 .   ? 99.01933  -33.63053 -29.81091 1.000 61.85172  ? 591 HOH A O   1 
HETATM 5128 O  O   . HOH G 4 .   ? 69.40079  -6.33614  -4.67769  1.000 50.30230  ? 592 HOH A O   1 
HETATM 5129 O  O   . HOH G 4 .   ? 102.61894 -6.11133  -27.68245 1.000 58.21524  ? 593 HOH A O   1 
HETATM 5130 O  O   . HOH G 4 .   ? 85.09334  -27.40219 -11.65788 1.000 55.51321  ? 594 HOH A O   1 
HETATM 5131 O  O   . HOH G 4 .   ? 99.30782  -20.04221 -38.05366 1.000 48.62018  ? 595 HOH A O   1 
HETATM 5132 O  O   . HOH G 4 .   ? 104.63348 -6.98951  -19.70330 1.000 50.41313  ? 596 HOH A O   1 
HETATM 5133 O  O   . HOH G 4 .   ? 80.30541  -23.52448 -20.06174 1.000 61.81704  ? 597 HOH A O   1 
HETATM 5134 O  O   . HOH G 4 .   ? 96.75412  -29.55370 -16.17493 1.000 48.07561  ? 598 HOH A O   1 
HETATM 5135 O  O   . HOH G 4 .   ? 97.70458  -5.79996  -27.66304 1.000 40.02919  ? 599 HOH A O   1 
HETATM 5136 O  O   . HOH G 4 .   ? 78.41162  -11.00073 -37.24919 1.000 63.96063  ? 600 HOH A O   1 
HETATM 5137 O  O   . HOH G 4 .   ? 94.47257  -30.03135 -35.19952 1.000 52.61059  ? 601 HOH A O   1 
HETATM 5138 O  O   . HOH G 4 .   ? 96.545    -0.557    -34.181   1.000 55.89227  ? 602 HOH A O   1 
HETATM 5139 O  O   . HOH G 4 .   ? 96.45875  -7.49873  -11.75075 1.000 52.98203  ? 603 HOH A O   1 
HETATM 5140 O  O   . HOH G 4 .   ? 80.08154  -19.06380 -21.09887 1.000 43.45636  ? 604 HOH A O   1 
HETATM 5141 O  O   . HOH G 4 .   ? 78.71270  -18.87413 7.02205   1.000 51.62948  ? 605 HOH A O   1 
HETATM 5142 O  O   . HOH G 4 .   ? 73.71917  -12.71912 5.09259   1.000 71.33039  ? 606 HOH A O   1 
HETATM 5143 O  O   . HOH G 4 .   ? 77.23616  -21.34994 -13.61787 1.000 47.94708  ? 607 HOH A O   1 
HETATM 5144 O  O   . HOH G 4 .   ? 75.67911  -20.16156 -40.06406 1.000 66.88997  ? 608 HOH A O   1 
HETATM 5145 O  O   . HOH G 4 .   ? 60.66691  -10.24498 -14.86062 1.000 66.47481  ? 609 HOH A O   1 
HETATM 5146 O  O   . HOH G 4 .   ? 90.088    -16.860   8.055     1.000 58.47592  ? 610 HOH A O   1 
HETATM 5147 O  O   . HOH G 4 .   ? 84.04253  -26.27181 -14.31147 1.000 48.56665  ? 611 HOH A O   1 
HETATM 5148 O  O   . HOH G 4 .   ? 78.18784  -23.32578 -35.48191 1.000 53.53424  ? 612 HOH A O   1 
HETATM 5149 O  O   . HOH G 4 .   ? 85.48391  -30.12410 -28.30712 1.000 55.57658  ? 613 HOH A O   1 
HETATM 5150 O  O   . HOH G 4 .   ? 75.57664  -16.47312 -34.03673 1.000 66.97953  ? 614 HOH A O   1 
HETATM 5151 O  O   . HOH G 4 .   ? 95.49468  -21.72668 -44.82124 1.000 62.02647  ? 615 HOH A O   1 
HETATM 5152 O  O   . HOH G 4 .   ? 86.98262  -25.76687 -9.27591  1.000 49.65777  ? 616 HOH A O   1 
HETATM 5153 O  O   . HOH G 4 .   ? 90.24256  -1.54968  -29.75401 1.000 39.36113  ? 617 HOH A O   1 
HETATM 5154 O  O   . HOH G 4 .   ? 93.04682  -22.70588 3.92579   1.000 54.62974  ? 618 HOH A O   1 
HETATM 5155 O  O   . HOH G 4 .   ? 84.02608  -5.18573  -37.45862 1.000 58.73408  ? 619 HOH A O   1 
HETATM 5156 O  O   . HOH G 4 .   ? 102.24907 -8.08489  -17.71534 1.000 46.52048  ? 620 HOH A O   1 
HETATM 5157 O  O   . HOH G 4 .   ? 86.19834  -12.34306 0.33365   1.000 56.11453  ? 621 HOH A O   1 
HETATM 5158 O  O   . HOH G 4 .   ? 84.70005  -26.41734 4.74544   1.000 54.37765  ? 622 HOH A O   1 
HETATM 5159 O  O   . HOH G 4 .   ? 86.60357  -10.39197 -17.02682 1.000 42.31077  ? 623 HOH A O   1 
HETATM 5160 O  O   . HOH G 4 .   ? 90.14737  -24.91215 -2.85267  1.000 42.15128  ? 624 HOH A O   1 
HETATM 5161 O  O   . HOH G 4 .   ? 78.76133  -17.27827 -30.42183 1.000 64.62441  ? 625 HOH A O   1 
HETATM 5162 O  O   . HOH G 4 .   ? 100.88897 -26.44381 -31.06754 1.000 47.18863  ? 626 HOH A O   1 
HETATM 5163 O  O   . HOH G 4 .   ? 90.89985  -28.27287 -7.78926  1.000 57.11340  ? 627 HOH A O   1 
HETATM 5164 O  O   . HOH G 4 .   ? 84.47723  -0.21360  -32.17787 1.000 54.89023  ? 628 HOH A O   1 
HETATM 5165 O  O   . HOH G 4 .   ? 82.70722  4.06546   -41.71484 1.000 53.24075  ? 629 HOH A O   1 
HETATM 5166 O  O   . HOH G 4 .   ? 96.056    -5.791    -48.535   1.000 45.01555  ? 630 HOH A O   1 
HETATM 5167 O  O   . HOH G 4 .   ? 103.20809 0.69927   -21.77489 1.000 62.02359  ? 631 HOH A O   1 
HETATM 5168 O  O   . HOH G 4 .   ? 101.30639 -28.71053 -26.61458 1.000 67.45289  ? 632 HOH A O   1 
HETATM 5169 O  O   . HOH G 4 .   ? 81.34070  -21.20827 -44.46170 1.000 59.73540  ? 633 HOH A O   1 
HETATM 5170 O  O   . HOH G 4 .   ? 83.90088  -3.06616  -8.55999  1.000 47.57888  ? 634 HOH A O   1 
HETATM 5171 O  O   . HOH G 4 .   ? 97.08561  -28.14773 -9.11083  1.000 43.12465  ? 635 HOH A O   1 
HETATM 5172 O  O   . HOH G 4 .   ? 81.001    -15.096   11.532    1.000 62.94086  ? 636 HOH A O   1 
HETATM 5173 O  O   . HOH G 4 .   ? 87.82955  -28.12737 -41.25118 1.000 59.87002  ? 637 HOH A O   1 
HETATM 5174 O  O   . HOH G 4 .   ? 84.72112  -15.36159 -43.76239 1.000 59.56719  ? 638 HOH A O   1 
HETATM 5175 O  O   . HOH G 4 .   ? 76.49519  -14.42937 -35.72773 1.000 64.59329  ? 639 HOH A O   1 
HETATM 5176 O  O   . HOH G 4 .   ? 92.24292  -23.65187 -4.09239  1.000 45.72609  ? 640 HOH A O   1 
HETATM 5177 O  O   . HOH G 4 .   ? 81.85010  -29.46456 -17.79613 1.000 63.31222  ? 641 HOH A O   1 
HETATM 5178 O  O   . HOH G 4 .   ? 77.57129  -19.95935 -34.75962 1.000 63.33196  ? 642 HOH A O   1 
HETATM 5179 O  O   . HOH G 4 .   ? 89.51770  4.54196   -28.85925 1.000 75.55280  ? 643 HOH A O   1 
HETATM 5180 O  O   . HOH G 4 .   ? 86.02077  -26.45790 2.78253   1.000 51.96591  ? 644 HOH A O   1 
HETATM 5181 O  O   . HOH G 4 .   ? 78.50110  -21.53875 -18.71638 1.000 61.30650  ? 645 HOH A O   1 
HETATM 5182 O  O   . HOH G 4 .   ? 96.43187  -9.14148  -49.37232 1.000 62.40580  ? 646 HOH A O   1 
HETATM 5183 O  O   . HOH G 4 .   ? 98.595    -5.017    -49.133   1.000 68.63243  ? 647 HOH A O   1 
HETATM 5184 O  O   . HOH G 4 .   ? 102.47086 -9.99863  -26.20151 1.000 64.46033  ? 648 HOH A O   1 
HETATM 5185 O  O   . HOH G 4 .   ? 99.35153  -24.89997 -21.78386 1.000 57.96654  ? 649 HOH A O   1 
HETATM 5186 O  O   . HOH G 4 .   ? 102.06274 -22.23654 -29.55384 1.000 54.27624  ? 650 HOH A O   1 
HETATM 5187 O  O   . HOH G 4 .   ? 102.10616 -14.10079 -22.07280 1.000 50.13762  ? 651 HOH A O   1 
HETATM 5188 O  O   . HOH G 4 .   ? 72.99686  -21.93160 -10.53627 1.000 44.43042  ? 652 HOH A O   1 
HETATM 5189 O  O   . HOH G 4 .   ? 101.33888 -5.25341  -37.35802 1.000 54.60443  ? 653 HOH A O   1 
HETATM 5190 O  O   . HOH G 4 .   ? 102.25533 -7.29657  -29.97641 1.000 58.78504  ? 654 HOH A O   1 
HETATM 5191 O  O   . HOH G 4 .   ? 100.96524 -3.54034  -35.72881 1.000 58.44914  ? 655 HOH A O   1 
HETATM 5192 O  O   . HOH G 4 .   ? 95.63218  -26.43855 -6.90725  1.000 58.43683  ? 656 HOH A O   1 
HETATM 5193 O  O   . HOH G 4 .   ? 83.16431  -13.30922 -43.04102 1.000 72.23148  ? 657 HOH A O   1 
HETATM 5194 O  O   . HOH G 4 .   ? 91.280    -7.338    -49.627   1.000 54.71438  ? 658 HOH A O   1 
HETATM 5195 O  O   . HOH G 4 .   ? 72.16985  -11.41484 3.30738   1.000 71.24504  ? 659 HOH A O   1 
HETATM 5196 O  O   . HOH G 4 .   ? 93.56700  -30.99499 -19.98135 1.000 64.46852  ? 660 HOH A O   1 
HETATM 5197 O  O   . HOH G 4 .   ? 103.90819 -14.26100 -31.24608 1.000 66.59387  ? 661 HOH A O   1 
HETATM 5198 O  O   . HOH G 4 .   ? 76.44544  -18.09279 -35.68216 1.000 69.97100  ? 662 HOH A O   1 
HETATM 5199 O  O   . HOH G 4 .   ? 94.86798  -24.60617 -5.60066  1.000 55.35856  ? 663 HOH A O   1 
HETATM 5200 O  O   . HOH G 4 .   ? 75.81054  -17.51748 9.46476   1.000 61.94805  ? 664 HOH A O   1 
HETATM 5201 O  O   . HOH G 4 .   ? 96.487    1.743     -34.879   1.000 58.82433  ? 665 HOH A O   1 
HETATM 5202 O  O   . HOH G 4 .   ? 99.68145  -26.01722 -24.33774 1.000 56.40159  ? 666 HOH A O   1 
HETATM 5203 O  O   . HOH G 4 .   ? 79.98168  -22.19393 -13.42505 1.000 51.14586  ? 667 HOH A O   1 
HETATM 5204 O  O   . HOH G 4 .   ? 103.00982 -3.16475  -33.22451 1.000 58.47515  ? 668 HOH A O   1 
HETATM 5205 O  O   . HOH G 4 .   ? 97.71316  -21.91329 -44.40157 1.000 65.51854  ? 669 HOH A O   1 
HETATM 5206 O  O   . HOH G 4 .   ? 103.47093 -6.37059  -37.12709 1.000 56.71717  ? 670 HOH A O   1 
HETATM 5207 O  O   . HOH G 4 .   ? 90.11820  -27.81699 -2.37769  1.000 60.52050  ? 671 HOH A O   1 
HETATM 5208 O  O   . HOH G 4 .   ? 100.09737 -21.29160 -40.27807 1.000 59.28819  ? 672 HOH A O   1 
HETATM 5209 O  O   . HOH G 4 .   ? 80.15009  -22.98619 -17.76686 1.000 62.47608  ? 673 HOH A O   1 
HETATM 5210 O  O   . HOH G 4 .   ? 76.25432  -18.91691 7.11124   1.000 54.61968  ? 674 HOH A O   1 
HETATM 5211 O  O   . HOH G 4 .   ? 95.25422  -32.51550 -34.15347 1.000 60.36935  ? 675 HOH A O   1 
HETATM 5212 O  O   . HOH G 4 .   ? 104.49571 -9.40264  -29.29753 1.000 78.77076  ? 676 HOH A O   1 
HETATM 5213 O  O   . HOH H 4 .   ? 71.05374  -53.45856 -25.89957 1.000 61.47684  ? 401 HOH B O   1 
HETATM 5214 O  O   . HOH H 4 .   ? 56.43422  -47.73499 -29.05081 1.000 60.92609  ? 402 HOH B O   1 
HETATM 5215 O  O   . HOH H 4 .   ? 49.40460  -57.26822 -4.98984  1.000 58.59121  ? 403 HOH B O   1 
HETATM 5216 O  O   . HOH H 4 .   ? 48.59233  -49.06162 -6.31729  1.000 55.83651  ? 404 HOH B O   1 
HETATM 5217 O  O   . HOH H 4 .   ? 59.22062  -35.65236 -26.27066 1.000 56.15612  ? 405 HOH B O   1 
HETATM 5218 O  O   . HOH H 4 .   ? 45.36362  -46.44389 -4.13157  1.000 62.62669  ? 406 HOH B O   1 
HETATM 5219 O  O   . HOH H 4 .   ? 75.03870  -27.26727 -5.84523  1.000 46.96356  ? 407 HOH B O   1 
HETATM 5220 O  O   . HOH H 4 .   ? 49.80270  -39.40418 -21.02468 1.000 49.07747  ? 408 HOH B O   1 
HETATM 5221 O  O   . HOH H 4 .   ? 59.04991  -21.05965 -14.86394 1.000 57.27609  ? 409 HOH B O   1 
HETATM 5222 O  O   . HOH H 4 .   ? 65.32248  -22.48156 -12.38476 1.000 46.91350  ? 410 HOH B O   1 
HETATM 5223 O  O   . HOH H 4 .   ? 79.29612  -34.02214 -19.06991 1.000 55.88366  ? 411 HOH B O   1 
HETATM 5224 O  O   . HOH H 4 .   ? 45.14873  -36.36623 -7.62945  1.000 59.71415  ? 412 HOH B O   1 
HETATM 5225 O  O   . HOH H 4 .   ? 49.21880  -43.36846 7.81514   1.000 60.15445  ? 413 HOH B O   1 
HETATM 5226 O  O   . HOH H 4 .   ? 49.92640  -53.25639 -2.29967  1.000 52.88759  ? 414 HOH B O   1 
HETATM 5227 O  O   . HOH H 4 .   ? 59.02540  -27.44236 -9.82287  1.000 47.32586  ? 415 HOH B O   1 
HETATM 5228 O  O   . HOH H 4 .   ? 46.05543  -34.34726 -18.09998 1.000 62.61223  ? 416 HOH B O   1 
HETATM 5229 O  O   . HOH H 4 .   ? 47.81696  -45.46390 -8.02011  1.000 62.91488  ? 417 HOH B O   1 
HETATM 5230 O  O   . HOH H 4 .   ? 61.16492  -31.54732 5.28242   1.000 48.46283  ? 418 HOH B O   1 
HETATM 5231 O  O   . HOH H 4 .   ? 87.01824  -52.84298 -5.44707  1.000 68.02715  ? 419 HOH B O   1 
HETATM 5232 O  O   . HOH H 4 .   ? 50.21675  -58.05208 -12.51812 1.000 59.30316  ? 420 HOH B O   1 
HETATM 5233 O  O   . HOH H 4 .   ? 65.99762  -34.75102 -13.82596 1.000 44.63845  ? 421 HOH B O   1 
HETATM 5234 O  O   . HOH H 4 .   ? 63.38635  -14.69935 -13.69802 1.000 59.60277  ? 422 HOH B O   1 
HETATM 5235 O  O   . HOH H 4 .   ? 76.04893  -44.92687 -13.84507 1.000 64.73602  ? 423 HOH B O   1 
HETATM 5236 O  O   . HOH H 4 .   ? 48.89254  -45.17144 -22.76002 1.000 54.85737  ? 424 HOH B O   1 
HETATM 5237 O  O   . HOH H 4 .   ? 84.75974  -48.73234 -10.34352 1.000 61.82747  ? 425 HOH B O   1 
HETATM 5238 O  O   . HOH H 4 .   ? 51.73333  -27.91642 3.63996   1.000 56.90717  ? 426 HOH B O   1 
HETATM 5239 O  O   . HOH H 4 .   ? 55.45812  -23.43322 -11.06999 1.000 57.29256  ? 427 HOH B O   1 
HETATM 5240 O  O   . HOH H 4 .   ? 65.31845  -48.25443 -0.12868  1.000 55.25363  ? 428 HOH B O   1 
HETATM 5241 O  O   . HOH H 4 .   ? 90.09957  -31.12646 -12.09640 1.000 57.30755  ? 429 HOH B O   1 
HETATM 5242 O  O   . HOH H 4 .   ? 69.04301  -47.86708 2.65113   1.000 69.01362  ? 430 HOH B O   1 
HETATM 5243 O  O   . HOH H 4 .   ? 65.67530  -50.80118 -26.01504 1.000 55.94270  ? 431 HOH B O   1 
HETATM 5244 O  O   . HOH H 4 .   ? 51.03987  -49.90096 5.40304   1.000 60.81443  ? 432 HOH B O   1 
HETATM 5245 O  O   . HOH H 4 .   ? 62.20016  -54.39432 -13.02770 1.000 50.92201  ? 433 HOH B O   1 
HETATM 5246 O  O   . HOH H 4 .   ? 60.61050  -55.82962 -8.60817  1.000 40.99473  ? 434 HOH B O   1 
HETATM 5247 O  O   . HOH H 4 .   ? 85.42105  -30.98589 -11.29246 1.000 48.13174  ? 435 HOH B O   1 
HETATM 5248 O  O   . HOH H 4 .   ? 48.64189  -45.19743 -20.04812 1.000 58.53164  ? 436 HOH B O   1 
HETATM 5249 O  O   . HOH H 4 .   ? 74.24748  -21.09123 6.52414   1.000 47.34646  ? 437 HOH B O   1 
HETATM 5250 O  O   . HOH H 4 .   ? 69.14912  -49.58505 4.55545   1.000 62.89574  ? 438 HOH B O   1 
HETATM 5251 O  O   . HOH H 4 .   ? 45.74092  -44.75052 -12.76191 1.000 62.18999  ? 439 HOH B O   1 
HETATM 5252 O  O   . HOH H 4 .   ? 67.77202  -32.20919 -23.22304 1.000 57.52637  ? 440 HOH B O   1 
HETATM 5253 O  O   . HOH H 4 .   ? 59.25054  -54.55062 -14.75080 1.000 50.86642  ? 441 HOH B O   1 
HETATM 5254 O  O   . HOH H 4 .   ? 63.12692  -33.92502 12.04518  1.000 61.32474  ? 442 HOH B O   1 
HETATM 5255 O  O   . HOH H 4 .   ? 47.97945  -24.82158 -10.54823 1.000 62.56656  ? 443 HOH B O   1 
HETATM 5256 O  O   . HOH H 4 .   ? 71.59775  -19.55797 -10.47941 1.000 45.36004  ? 444 HOH B O   1 
HETATM 5257 O  O   . HOH H 4 .   ? 59.37017  -17.91242 0.96278   1.000 60.93167  ? 445 HOH B O   1 
HETATM 5258 O  O   . HOH H 4 .   ? 58.26256  -50.06957 -1.99073  1.000 42.83611  ? 446 HOH B O   1 
HETATM 5259 O  O   . HOH H 4 .   ? 46.81692  -31.76563 -1.99739  1.000 63.01140  ? 447 HOH B O   1 
HETATM 5260 O  O   . HOH H 4 .   ? 64.82801  -32.83285 -15.33836 1.000 43.01568  ? 448 HOH B O   1 
HETATM 5261 O  O   . HOH H 4 .   ? 60.91412  -52.89328 -7.90850  1.000 40.64031  ? 449 HOH B O   1 
HETATM 5262 O  O   . HOH H 4 .   ? 47.19792  -44.01091 5.93726   1.000 60.05989  ? 450 HOH B O   1 
HETATM 5263 O  O   . HOH H 4 .   ? 71.13732  -47.05508 -11.49626 1.000 67.65590  ? 451 HOH B O   1 
HETATM 5264 O  O   . HOH H 4 .   ? 71.48787  -23.77450 -11.94564 1.000 57.07528  ? 452 HOH B O   1 
HETATM 5265 O  O   . HOH H 4 .   ? 73.89812  -21.95425 9.88774   1.000 61.45849  ? 453 HOH B O   1 
HETATM 5266 O  O   . HOH H 4 .   ? 53.72834  -17.37052 -12.62598 1.000 58.65884  ? 454 HOH B O   1 
HETATM 5267 O  O   . HOH H 4 .   ? 77.80794  -33.58542 5.93466   1.000 50.59045  ? 455 HOH B O   1 
HETATM 5268 O  O   . HOH H 4 .   ? 61.51770  -36.55809 5.79202   1.000 48.98405  ? 456 HOH B O   1 
HETATM 5269 O  O   . HOH H 4 .   ? 47.60900  -9.03563  -2.51387  1.000 71.25393  ? 457 HOH B O   1 
HETATM 5270 O  O   . HOH H 4 .   ? 48.90449  -42.85238 -23.97714 1.000 61.87126  ? 458 HOH B O   1 
HETATM 5271 O  O   . HOH H 4 .   ? 53.26996  -36.61595 10.04174  1.000 59.92586  ? 459 HOH B O   1 
HETATM 5272 O  O   . HOH H 4 .   ? 52.90341  -47.64117 -7.13165  1.000 48.22153  ? 460 HOH B O   1 
HETATM 5273 O  O   . HOH H 4 .   ? 67.05693  -33.67797 -11.70350 1.000 39.24397  ? 461 HOH B O   1 
HETATM 5274 O  O   . HOH H 4 .   ? 64.78678  -34.04325 -26.25125 1.000 59.88141  ? 462 HOH B O   1 
HETATM 5275 O  O   . HOH H 4 .   ? 81.09105  -26.32592 6.21754   1.000 57.17590  ? 463 HOH B O   1 
HETATM 5276 O  O   . HOH H 4 .   ? 66.62891  -20.20891 5.92704   1.000 58.59893  ? 464 HOH B O   1 
HETATM 5277 O  O   . HOH H 4 .   ? 84.10244  -31.53538 -5.67391  1.000 55.50444  ? 465 HOH B O   1 
HETATM 5278 O  O   . HOH H 4 .   ? 62.44576  -60.94953 -4.20246  1.000 52.10619  ? 466 HOH B O   1 
HETATM 5279 O  O   . HOH H 4 .   ? 59.95834  -29.13268 4.93184   1.000 52.69277  ? 467 HOH B O   1 
HETATM 5280 O  O   . HOH H 4 .   ? 86.25541  -31.96246 -7.84298  1.000 51.13229  ? 468 HOH B O   1 
HETATM 5281 O  O   . HOH H 4 .   ? 64.62795  -53.58384 -3.60844  1.000 55.65515  ? 469 HOH B O   1 
HETATM 5282 O  O   . HOH H 4 .   ? 46.55197  -40.83434 -8.24067  1.000 59.04747  ? 470 HOH B O   1 
HETATM 5283 O  O   . HOH H 4 .   ? 96.77476  -36.75896 -3.69932  1.000 59.67645  ? 471 HOH B O   1 
HETATM 5284 O  O   . HOH H 4 .   ? 52.09016  -42.57881 11.73578  1.000 65.52484  ? 472 HOH B O   1 
HETATM 5285 O  O   . HOH H 4 .   ? 58.07654  -27.52229 -13.68403 1.000 48.22945  ? 473 HOH B O   1 
HETATM 5286 O  O   . HOH H 4 .   ? 76.26037  -43.44052 -10.08992 1.000 61.28230  ? 474 HOH B O   1 
HETATM 5287 O  O   . HOH H 4 .   ? 56.87842  -34.51435 -12.67270 1.000 49.12387  ? 475 HOH B O   1 
HETATM 5288 O  O   . HOH H 4 .   ? 66.80799  -28.29771 -12.11878 1.000 51.43698  ? 476 HOH B O   1 
HETATM 5289 O  O   . HOH H 4 .   ? 71.89598  -51.55866 -31.66167 1.000 63.58151  ? 477 HOH B O   1 
HETATM 5290 O  O   . HOH H 4 .   ? 57.31114  -50.80256 0.89199   1.000 53.52353  ? 478 HOH B O   1 
HETATM 5291 O  O   . HOH H 4 .   ? 85.75684  -41.67055 4.89528   1.000 63.57744  ? 479 HOH B O   1 
HETATM 5292 O  O   . HOH H 4 .   ? 52.28539  -32.49127 -22.67375 1.000 60.54990  ? 480 HOH B O   1 
HETATM 5293 O  O   . HOH H 4 .   ? 49.38246  -46.25982 -5.94210  1.000 53.92204  ? 481 HOH B O   1 
HETATM 5294 O  O   . HOH H 4 .   ? 49.77434  -45.91081 -3.26757  1.000 58.82451  ? 482 HOH B O   1 
HETATM 5295 O  O   . HOH H 4 .   ? 94.122    -44.108   -3.410    1.000 48.76725  ? 483 HOH B O   1 
HETATM 5296 O  O   . HOH H 4 .   ? 81.10843  -55.70499 -14.30342 1.000 64.73153  ? 484 HOH B O   1 
HETATM 5297 O  O   . HOH H 4 .   ? 87.05565  -31.89503 1.70210   1.000 68.93232  ? 485 HOH B O   1 
HETATM 5298 O  O   . HOH H 4 .   ? 68.66919  -49.83666 -31.51611 1.000 61.22783  ? 486 HOH B O   1 
HETATM 5299 O  O   . HOH H 4 .   ? 84.21137  -52.49254 -1.36930  1.000 65.70888  ? 487 HOH B O   1 
HETATM 5300 O  O   . HOH H 4 .   ? 45.06557  -43.58078 -6.83972  1.000 71.87281  ? 488 HOH B O   1 
HETATM 5301 O  O   . HOH H 4 .   ? 88.76011  -40.15436 -15.82637 1.000 63.50077  ? 489 HOH B O   1 
HETATM 5302 O  O   . HOH H 4 .   ? 55.58655  -45.11216 -27.86253 1.000 55.92735  ? 490 HOH B O   1 
HETATM 5303 O  O   . HOH H 4 .   ? 46.63893  -34.13303 -0.98923  1.000 61.21665  ? 491 HOH B O   1 
HETATM 5304 O  O   . HOH H 4 .   ? 91.38644  -46.16766 -1.28166  1.000 52.15310  ? 492 HOH B O   1 
HETATM 5305 O  O   . HOH H 4 .   ? 58.42277  -33.19890 -14.59286 1.000 48.03104  ? 493 HOH B O   1 
HETATM 5306 O  O   . HOH H 4 .   ? 58.58871  -8.94299  -12.03176 1.000 62.42639  ? 494 HOH B O   1 
HETATM 5307 O  O   . HOH H 4 .   ? 60.79865  -34.48658 4.27769   1.000 54.65434  ? 495 HOH B O   1 
HETATM 5308 O  O   . HOH H 4 .   ? 46.34758  -54.64004 -10.14851 1.000 56.71671  ? 496 HOH B O   1 
HETATM 5309 O  O   . HOH H 4 .   ? 75.36276  -50.38627 -3.19219  1.000 57.76123  ? 497 HOH B O   1 
HETATM 5310 O  O   . HOH H 4 .   ? 55.30448  -36.31304 -13.84875 1.000 49.63255  ? 498 HOH B O   1 
HETATM 5311 O  O   . HOH H 4 .   ? 68.85040  -25.40401 -11.40232 1.000 52.65347  ? 499 HOH B O   1 
HETATM 5312 O  O   . HOH H 4 .   ? 71.82534  -34.19497 10.13543  1.000 57.77317  ? 500 HOH B O   1 
HETATM 5313 O  O   . HOH H 4 .   ? 70.13222  -34.05395 -20.49789 1.000 52.92472  ? 501 HOH B O   1 
HETATM 5314 O  O   . HOH H 4 .   ? 59.51749  -32.91069 -2.97370  1.000 45.22482  ? 502 HOH B O   1 
HETATM 5315 O  O   . HOH H 4 .   ? 75.79299  -42.33937 -12.20744 1.000 65.80655  ? 503 HOH B O   1 
HETATM 5316 O  O   . HOH H 4 .   ? 70.98483  -37.13978 -25.52561 1.000 59.07536  ? 504 HOH B O   1 
HETATM 5317 O  O   . HOH H 4 .   ? 57.15902  -48.28274 1.07683   1.000 49.19485  ? 505 HOH B O   1 
HETATM 5318 O  O   . HOH H 4 .   ? 55.49008  -15.45164 -13.21193 1.000 53.47603  ? 506 HOH B O   1 
HETATM 5319 O  O   . HOH H 4 .   ? 65.59482  -13.36710 5.62698   1.000 61.04377  ? 507 HOH B O   1 
HETATM 5320 O  O   . HOH H 4 .   ? 66.72835  -31.14195 -15.85603 1.000 47.44228  ? 508 HOH B O   1 
HETATM 5321 O  O   . HOH H 4 .   ? 48.65034  -29.77427 -0.16731  1.000 57.34699  ? 509 HOH B O   1 
HETATM 5322 O  O   . HOH H 4 .   ? 71.18470  -43.38771 -13.89841 1.000 68.87744  ? 510 HOH B O   1 
HETATM 5323 O  O   . HOH H 4 .   ? 90.27531  -45.48289 1.71371   1.000 59.72156  ? 511 HOH B O   1 
HETATM 5324 O  O   . HOH H 4 .   ? 69.28852  -53.81813 -19.97961 1.000 62.93754  ? 512 HOH B O   1 
HETATM 5325 O  O   . HOH H 4 .   ? 71.72124  -45.51143 -17.10676 1.000 54.89827  ? 513 HOH B O   1 
HETATM 5326 O  O   . HOH H 4 .   ? 86.10204  -31.77991 -20.70817 1.000 57.26891  ? 514 HOH B O   1 
HETATM 5327 O  O   . HOH H 4 .   ? 55.12864  -34.77711 9.26555   1.000 54.99240  ? 515 HOH B O   1 
HETATM 5328 O  O   . HOH H 4 .   ? 69.00983  -45.95444 -4.44604  1.000 62.24286  ? 516 HOH B O   1 
HETATM 5329 O  O   . HOH H 4 .   ? 60.50357  -26.77288 6.76338   1.000 56.27790  ? 517 HOH B O   1 
HETATM 5330 O  O   . HOH H 4 .   ? 66.09691  -56.49984 -2.99205  1.000 67.29611  ? 518 HOH B O   1 
HETATM 5331 O  O   . HOH H 4 .   ? 81.85471  -47.65162 -16.26337 1.000 64.87955  ? 519 HOH B O   1 
HETATM 5332 O  O   . HOH H 4 .   ? 66.53109  -51.43890 0.30500   1.000 66.33295  ? 520 HOH B O   1 
HETATM 5333 O  O   . HOH H 4 .   ? 53.94338  -59.73237 -1.35315  1.000 67.66758  ? 521 HOH B O   1 
HETATM 5334 O  O   . HOH H 4 .   ? 65.06646  -25.97898 -15.08261 1.000 63.30078  ? 522 HOH B O   1 
HETATM 5335 O  O   . HOH H 4 .   ? 88.91718  -34.76953 2.10533   1.000 66.82956  ? 523 HOH B O   1 
HETATM 5336 O  O   . HOH H 4 .   ? 87.98635  -44.87002 -10.16678 1.000 61.69692  ? 524 HOH B O   1 
HETATM 5337 O  O   . HOH H 4 .   ? 48.00200  -55.27983 -5.87114  1.000 55.16031  ? 525 HOH B O   1 
HETATM 5338 O  O   . HOH H 4 .   ? 67.46095  -55.70621 -5.52051  1.000 75.97061  ? 526 HOH B O   1 
HETATM 5339 O  O   . HOH H 4 .   ? 49.237    -60.582   -19.180   1.000 60.29357  ? 527 HOH B O   1 
HETATM 5340 O  O   . HOH H 4 .   ? 68.13205  -30.55042 -13.36573 1.000 53.46675  ? 528 HOH B O   1 
HETATM 5341 O  O   . HOH H 4 .   ? 69.20006  -37.71620 -26.86146 1.000 61.89515  ? 529 HOH B O   1 
HETATM 5342 O  O   . HOH H 4 .   ? 69.72277  -31.38842 -21.30348 1.000 58.86459  ? 530 HOH B O   1 
HETATM 5343 O  O   . HOH H 4 .   ? 91.01762  -34.01181 1.54380   1.000 71.00822  ? 531 HOH B O   1 
HETATM 5344 O  O   . HOH H 4 .   ? 90.49443  -39.84323 4.96184   1.000 71.34074  ? 532 HOH B O   1 
HETATM 5345 O  O   . HOH H 4 .   ? 66.50635  -49.56818 -3.82500  1.000 59.14097  ? 533 HOH B O   1 
HETATM 5346 O  O   . HOH H 4 .   ? 68.73127  -56.51903 -8.64628  1.000 73.91464  ? 534 HOH B O   1 
HETATM 5347 O  O   . HOH H 4 .   ? 71.39486  -45.00377 -9.93849  1.000 68.31974  ? 535 HOH B O   1 
HETATM 5348 O  O   . HOH H 4 .   ? 62.55688  -17.91485 4.17176   1.000 64.44637  ? 536 HOH B O   1 
HETATM 5349 O  O   . HOH H 4 .   ? 47.87111  -54.96293 -19.11563 1.000 68.77988  ? 537 HOH B O   1 
HETATM 5350 O  O   . HOH H 4 .   ? 91.51644  -33.07112 -13.37101 1.000 61.30414  ? 538 HOH B O   1 
HETATM 5351 O  O   . HOH H 4 .   ? 51.29580  -55.18112 -0.20744  1.000 61.06714  ? 539 HOH B O   1 
HETATM 5352 O  O   . HOH H 4 .   ? 88.43322  -28.69494 -6.39367  1.000 61.54489  ? 540 HOH B O   1 
HETATM 5353 O  O   . HOH H 4 .   ? 53.09382  -39.07744 10.38108  1.000 63.03873  ? 541 HOH B O   1 
HETATM 5354 O  O   . HOH H 4 .   ? 46.53017  -56.99026 -11.45288 1.000 66.22633  ? 542 HOH B O   1 
HETATM 5355 O  O   . HOH H 4 .   ? 64.60718  -18.13207 5.62251   1.000 61.36430  ? 543 HOH B O   1 
HETATM 5356 O  O   . HOH H 4 .   ? 61.18966  -62.83264 -2.53524  1.000 59.66123  ? 544 HOH B O   1 
HETATM 5357 O  O   . HOH H 4 .   ? 52.97682  -30.02047 -22.82311 1.000 65.46611  ? 545 HOH B O   1 
HETATM 5358 O  O   . HOH H 4 .   ? 70.65525  -46.92147 -8.41565  1.000 64.60690  ? 546 HOH B O   1 
HETATM 5359 O  O   . HOH H 4 .   ? 48.94233  -15.90403 1.99011   1.000 72.33646  ? 547 HOH B O   1 
HETATM 5360 O  O   . HOH H 4 .   ? 79.50355  -46.62427 2.00387   1.000 68.15771  ? 548 HOH B O   1 
HETATM 5361 O  O   . HOH H 4 .   ? 51.36714  -31.21368 -26.06493 1.000 75.52255  ? 549 HOH B O   1 
HETATM 5362 O  O   . HOH H 4 .   ? 66.00812  -25.36616 -12.71061 1.000 53.84750  ? 550 HOH B O   1 
HETATM 5363 O  O   . HOH H 4 .   ? 87.61168  -29.01053 -4.09120  1.000 60.92794  ? 551 HOH B O   1 
HETATM 5364 O  O   . HOH H 4 .   ? 69.94978  -10.73843 2.84129   1.000 72.53716  ? 552 HOH B O   1 
HETATM 5365 O  O   . HOH H 4 .   ? 73.49617  -14.02468 2.76094   1.000 60.55855  ? 553 HOH B O   1 
HETATM 5366 O  O   . HOH H 4 .   ? 72.26070  -19.36761 7.66550   1.000 62.05782  ? 554 HOH B O   1 
HETATM 5367 O  O   . HOH H 4 .   ? 90.34489  -29.50093 -3.96492  1.000 65.94078  ? 555 HOH B O   1 
HETATM 5368 O  O   . HOH H 4 .   ? 67.54741  -50.80610 -1.71589  1.000 69.38802  ? 556 HOH B O   1 
HETATM 5369 O  O   . HOH H 4 .   ? 84.47931  -44.81492 3.55387   1.000 68.89603  ? 557 HOH B O   1 
HETATM 5370 O  O   . HOH H 4 .   ? 66.660    -63.156   -3.322    1.000 64.61346  ? 558 HOH B O   1 
HETATM 5371 O  O   . HOH H 4 .   ? 50.14189  -15.05044 4.00512   1.000 74.75619  ? 559 HOH B O   1 
HETATM 5372 O  O   . HOH H 4 .   ? 82.01351  -46.16644 2.76154   1.000 69.86660  ? 560 HOH B O   1 
# 
