data_9C6K
# 
_entry.id   9C6K 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9C6K         pdb_00009c6k 10.2210/pdb9c6k/pdb 
WWPDB D_1000284893 ?            ?                   
EMDB  EMD-45249    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-12-04 
2 'Structure model' 1 1 2025-01-29 
3 'Structure model' 1 2 2025-02-05 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
3 3 'Structure model' 'Data collection'     
4 3 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
4 3 'Structure model' citation        
5 3 'Structure model' citation_author 
6 3 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_ISSN'         
4  2 'Structure model' '_citation.pdbx_database_id_DOI'    
5  2 'Structure model' '_citation.title'                   
6  2 'Structure model' '_citation.year'                    
7  2 'Structure model' '_em_admin.last_update'             
8  3 'Structure model' '_citation.journal_volume'          
9  3 'Structure model' '_citation.page_first'              
10 3 'Structure model' '_citation.page_last'               
11 3 'Structure model' '_citation.pdbx_database_id_PubMed' 
12 3 'Structure model' '_citation.title'                   
13 3 'Structure model' '_citation_author.identifier_ORCID' 
14 3 'Structure model' '_citation_author.name'             
15 3 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9C6K 
_pdbx_database_status.recvd_initial_deposition_date   2024-06-07 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'Cryo-EM structure of the TPP riboswitch embedded in an RNA scaffold bound to thiamine pyrophosphate' EMD-45249 
'associated EM volume' 
PDB  'Cryo-EM structure of the TPP riboswitch embedded in an RNA scaffold bound to thiamine pyrophosphate' 9C6K      unspecified 
EMDB 'Group IIC intron embedded with the TPP riboswitch'                                                   EMD-45248 
'other EM volume'      
PDB  'Group IIC intron embedded with the TPP riboswitch'                                                   9C6J      unspecified 
EMDB 'Cryo-EM structure of a group IIC intron RNA'                                                         EMD-45247 
'other EM volume'      
PDB  'Cryo-EM structure of a group IIC intron RNA'                                                         9C6I      unspecified 
EMDB 'Cryo-EM structure of the apo TPP riboswitch embedded in an RNA scaffold'                             EMD-45250 
'other EM volume'      
EMDB 'Cryo-EM Structure of a group IIC intron embedded in an RNP scaffold'                                 EMD-45251 
'other EM volume'      
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              ntoor@ucsd.edu 
_pdbx_contact_author.name_first         Navtej 
_pdbx_contact_author.name_last          Toor 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6134-163X 
# 
_audit_author.name               'Toor, N.' 
_audit_author.pdbx_ordinal       1 
_audit_author.identifier_ORCID   ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                880 
_citation.page_last                 880 
_citation.title                     'Scaffold-enabled high-resolution cryo-EM structure determination of RNA.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-55699-5 
_citation.pdbx_database_id_PubMed   39837824 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Haack, D.B.' 1 0000-0002-4926-7772 
primary 'Rudolfs, B.' 2 ?                   
primary 'Jin, S.'     3 ?                   
primary 'Khitun, A.'  4 ?                   
primary 'Weeks, K.M.' 5 0000-0002-6748-9985 
primary 'Toor, N.'    6 0000-0002-6134-163X 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'TPP riboswitch embedded in an RNA scaffold bound to thiamine pyrophosphate' 161102.484 1 ? ? ? ? 
2 non-polymer syn 'MAGNESIUM ION'                                                              24.305     6 ? ? ? ? 
3 non-polymer syn 'THIAMINE DIPHOSPHATE'                                                       425.314    1 ? ? ? ? 
4 non-polymer syn 'SODIUM ION'                                                                 22.990     2 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           polyribonucleotide 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;UUAUGUGUGCCCGGCAUGGGUGCAGUCUAUAGGGUGAGAGUCCCGAACUGUGAAGGCAGAAGUAACAGUUAGCCUAACGC
AAGGGUGUCCGUGGCGACAUGGAAUCUGAAGGAAGCGGACGGCAAACCUUCGGUCUGAGGAACACGAACUUCAUAUGAGG
CUAGGUAUCAAUGGAUGAGUUUGCAUAACAAAACAAAGUCCUUUCUGCCAAAGUUGGUACAGAGUAAAUGAAGCAGAUUG
AUGAAGGGAAAGACUGCAUUCUUACCCGGGGAGGUCUGGAAACAGAAGUCAGCAGAAGUCAUAGUACCCUCAGUACUCGG
GGUGCCCUUCUGCGUGAAGGCUGAGAAAUACCCGUAUCACCUGAUCUGGAUAAUGCCAGCGUAGGGAAGUGCUGAGGGGA
AGGACGGAACAAGUAUGGCGUUCGCGCCUAAGCUUGAACCACCGUAUACCGAACGGUACGUACGGUGGUGUGAGAGGAGU
UCGCUCUACUCUAUUAG
;
_entity_poly.pdbx_seq_one_letter_code_can   
;UUAUGUGUGCCCGGCAUGGGUGCAGUCUAUAGGGUGAGAGUCCCGAACUGUGAAGGCAGAAGUAACAGUUAGCCUAACGC
AAGGGUGUCCGUGGCGACAUGGAAUCUGAAGGAAGCGGACGGCAAACCUUCGGUCUGAGGAACACGAACUUCAUAUGAGG
CUAGGUAUCAAUGGAUGAGUUUGCAUAACAAAACAAAGUCCUUUCUGCCAAAGUUGGUACAGAGUAAAUGAAGCAGAUUG
AUGAAGGGAAAGACUGCAUUCUUACCCGGGGAGGUCUGGAAACAGAAGUCAGCAGAAGUCAUAGUACCCUCAGUACUCGG
GGUGCCCUUCUGCGUGAAGGCUGAGAAAUACCCGUAUCACCUGAUCUGGAUAAUGCCAGCGUAGGGAAGUGCUGAGGGGA
AGGACGGAACAAGUAUGGCGUUCGCGCCUAAGCUUGAACCACCGUAUACCGAACGGUACGUACGGUGGUGUGAGAGGAGU
UCGCUCUACUCUAUUAG
;
_entity_poly.pdbx_strand_id                 X 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'MAGNESIUM ION'        MG  
3 'THIAMINE DIPHOSPHATE' TPP 
4 'SODIUM ION'           NA  
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   U n 
1 2   U n 
1 3   A n 
1 4   U n 
1 5   G n 
1 6   U n 
1 7   G n 
1 8   U n 
1 9   G n 
1 10  C n 
1 11  C n 
1 12  C n 
1 13  G n 
1 14  G n 
1 15  C n 
1 16  A n 
1 17  U n 
1 18  G n 
1 19  G n 
1 20  G n 
1 21  U n 
1 22  G n 
1 23  C n 
1 24  A n 
1 25  G n 
1 26  U n 
1 27  C n 
1 28  U n 
1 29  A n 
1 30  U n 
1 31  A n 
1 32  G n 
1 33  G n 
1 34  G n 
1 35  U n 
1 36  G n 
1 37  A n 
1 38  G n 
1 39  A n 
1 40  G n 
1 41  U n 
1 42  C n 
1 43  C n 
1 44  C n 
1 45  G n 
1 46  A n 
1 47  A n 
1 48  C n 
1 49  U n 
1 50  G n 
1 51  U n 
1 52  G n 
1 53  A n 
1 54  A n 
1 55  G n 
1 56  G n 
1 57  C n 
1 58  A n 
1 59  G n 
1 60  A n 
1 61  A n 
1 62  G n 
1 63  U n 
1 64  A n 
1 65  A n 
1 66  C n 
1 67  A n 
1 68  G n 
1 69  U n 
1 70  U n 
1 71  A n 
1 72  G n 
1 73  C n 
1 74  C n 
1 75  U n 
1 76  A n 
1 77  A n 
1 78  C n 
1 79  G n 
1 80  C n 
1 81  A n 
1 82  A n 
1 83  G n 
1 84  G n 
1 85  G n 
1 86  U n 
1 87  G n 
1 88  U n 
1 89  C n 
1 90  C n 
1 91  G n 
1 92  U n 
1 93  G n 
1 94  G n 
1 95  C n 
1 96  G n 
1 97  A n 
1 98  C n 
1 99  A n 
1 100 U n 
1 101 G n 
1 102 G n 
1 103 A n 
1 104 A n 
1 105 U n 
1 106 C n 
1 107 U n 
1 108 G n 
1 109 A n 
1 110 A n 
1 111 G n 
1 112 G n 
1 113 A n 
1 114 A n 
1 115 G n 
1 116 C n 
1 117 G n 
1 118 G n 
1 119 A n 
1 120 C n 
1 121 G n 
1 122 G n 
1 123 C n 
1 124 A n 
1 125 A n 
1 126 A n 
1 127 C n 
1 128 C n 
1 129 U n 
1 130 U n 
1 131 C n 
1 132 G n 
1 133 G n 
1 134 U n 
1 135 C n 
1 136 U n 
1 137 G n 
1 138 A n 
1 139 G n 
1 140 G n 
1 141 A n 
1 142 A n 
1 143 C n 
1 144 A n 
1 145 C n 
1 146 G n 
1 147 A n 
1 148 A n 
1 149 C n 
1 150 U n 
1 151 U n 
1 152 C n 
1 153 A n 
1 154 U n 
1 155 A n 
1 156 U n 
1 157 G n 
1 158 A n 
1 159 G n 
1 160 G n 
1 161 C n 
1 162 U n 
1 163 A n 
1 164 G n 
1 165 G n 
1 166 U n 
1 167 A n 
1 168 U n 
1 169 C n 
1 170 A n 
1 171 A n 
1 172 U n 
1 173 G n 
1 174 G n 
1 175 A n 
1 176 U n 
1 177 G n 
1 178 A n 
1 179 G n 
1 180 U n 
1 181 U n 
1 182 U n 
1 183 G n 
1 184 C n 
1 185 A n 
1 186 U n 
1 187 A n 
1 188 A n 
1 189 C n 
1 190 A n 
1 191 A n 
1 192 A n 
1 193 A n 
1 194 C n 
1 195 A n 
1 196 A n 
1 197 A n 
1 198 G n 
1 199 U n 
1 200 C n 
1 201 C n 
1 202 U n 
1 203 U n 
1 204 U n 
1 205 C n 
1 206 U n 
1 207 G n 
1 208 C n 
1 209 C n 
1 210 A n 
1 211 A n 
1 212 A n 
1 213 G n 
1 214 U n 
1 215 U n 
1 216 G n 
1 217 G n 
1 218 U n 
1 219 A n 
1 220 C n 
1 221 A n 
1 222 G n 
1 223 A n 
1 224 G n 
1 225 U n 
1 226 A n 
1 227 A n 
1 228 A n 
1 229 U n 
1 230 G n 
1 231 A n 
1 232 A n 
1 233 G n 
1 234 C n 
1 235 A n 
1 236 G n 
1 237 A n 
1 238 U n 
1 239 U n 
1 240 G n 
1 241 A n 
1 242 U n 
1 243 G n 
1 244 A n 
1 245 A n 
1 246 G n 
1 247 G n 
1 248 G n 
1 249 A n 
1 250 A n 
1 251 A n 
1 252 G n 
1 253 A n 
1 254 C n 
1 255 U n 
1 256 G n 
1 257 C n 
1 258 A n 
1 259 U n 
1 260 U n 
1 261 C n 
1 262 U n 
1 263 U n 
1 264 A n 
1 265 C n 
1 266 C n 
1 267 C n 
1 268 G n 
1 269 G n 
1 270 G n 
1 271 G n 
1 272 A n 
1 273 G n 
1 274 G n 
1 275 U n 
1 276 C n 
1 277 U n 
1 278 G n 
1 279 G n 
1 280 A n 
1 281 A n 
1 282 A n 
1 283 C n 
1 284 A n 
1 285 G n 
1 286 A n 
1 287 A n 
1 288 G n 
1 289 U n 
1 290 C n 
1 291 A n 
1 292 G n 
1 293 C n 
1 294 A n 
1 295 G n 
1 296 A n 
1 297 A n 
1 298 G n 
1 299 U n 
1 300 C n 
1 301 A n 
1 302 U n 
1 303 A n 
1 304 G n 
1 305 U n 
1 306 A n 
1 307 C n 
1 308 C n 
1 309 C n 
1 310 U n 
1 311 C n 
1 312 A n 
1 313 G n 
1 314 U n 
1 315 A n 
1 316 C n 
1 317 U n 
1 318 C n 
1 319 G n 
1 320 G n 
1 321 G n 
1 322 G n 
1 323 U n 
1 324 G n 
1 325 C n 
1 326 C n 
1 327 C n 
1 328 U n 
1 329 U n 
1 330 C n 
1 331 U n 
1 332 G n 
1 333 C n 
1 334 G n 
1 335 U n 
1 336 G n 
1 337 A n 
1 338 A n 
1 339 G n 
1 340 G n 
1 341 C n 
1 342 U n 
1 343 G n 
1 344 A n 
1 345 G n 
1 346 A n 
1 347 A n 
1 348 A n 
1 349 U n 
1 350 A n 
1 351 C n 
1 352 C n 
1 353 C n 
1 354 G n 
1 355 U n 
1 356 A n 
1 357 U n 
1 358 C n 
1 359 A n 
1 360 C n 
1 361 C n 
1 362 U n 
1 363 G n 
1 364 A n 
1 365 U n 
1 366 C n 
1 367 U n 
1 368 G n 
1 369 G n 
1 370 A n 
1 371 U n 
1 372 A n 
1 373 A n 
1 374 U n 
1 375 G n 
1 376 C n 
1 377 C n 
1 378 A n 
1 379 G n 
1 380 C n 
1 381 G n 
1 382 U n 
1 383 A n 
1 384 G n 
1 385 G n 
1 386 G n 
1 387 A n 
1 388 A n 
1 389 G n 
1 390 U n 
1 391 G n 
1 392 C n 
1 393 U n 
1 394 G n 
1 395 A n 
1 396 G n 
1 397 G n 
1 398 G n 
1 399 G n 
1 400 A n 
1 401 A n 
1 402 G n 
1 403 G n 
1 404 A n 
1 405 C n 
1 406 G n 
1 407 G n 
1 408 A n 
1 409 A n 
1 410 C n 
1 411 A n 
1 412 A n 
1 413 G n 
1 414 U n 
1 415 A n 
1 416 U n 
1 417 G n 
1 418 G n 
1 419 C n 
1 420 G n 
1 421 U n 
1 422 U n 
1 423 C n 
1 424 G n 
1 425 C n 
1 426 G n 
1 427 C n 
1 428 C n 
1 429 U n 
1 430 A n 
1 431 A n 
1 432 G n 
1 433 C n 
1 434 U n 
1 435 U n 
1 436 G n 
1 437 A n 
1 438 A n 
1 439 C n 
1 440 C n 
1 441 A n 
1 442 C n 
1 443 C n 
1 444 G n 
1 445 U n 
1 446 A n 
1 447 U n 
1 448 A n 
1 449 C n 
1 450 C n 
1 451 G n 
1 452 A n 
1 453 A n 
1 454 C n 
1 455 G n 
1 456 G n 
1 457 U n 
1 458 A n 
1 459 C n 
1 460 G n 
1 461 U n 
1 462 A n 
1 463 C n 
1 464 G n 
1 465 G n 
1 466 U n 
1 467 G n 
1 468 G n 
1 469 U n 
1 470 G n 
1 471 U n 
1 472 G n 
1 473 A n 
1 474 G n 
1 475 A n 
1 476 G n 
1 477 G n 
1 478 A n 
1 479 G n 
1 480 U n 
1 481 U n 
1 482 C n 
1 483 G n 
1 484 C n 
1 485 U n 
1 486 C n 
1 487 U n 
1 488 A n 
1 489 C n 
1 490 U n 
1 491 C n 
1 492 U n 
1 493 A n 
1 494 U n 
1 495 U n 
1 496 A n 
1 497 G n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   497 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     562 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking' y "ADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P'      347.221 
C   'RNA linking' y "CYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O8 P'       323.197 
G   'RNA linking' y "GUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O8 P'      363.221 
MG  non-polymer   . 'MAGNESIUM ION'              ? 'Mg 2'                 24.305  
NA  non-polymer   . 'SODIUM ION'                 ? 'Na 1'                 22.990  
TPP non-polymer   . 'THIAMINE DIPHOSPHATE'       ? 'C12 H19 N4 O7 P2 S 1' 425.314 
U   'RNA linking' y "URIDINE-5'-MONOPHOSPHATE"   ? 'C9 H13 N2 O9 P'       324.181 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   U 1   -302 ?  ? ? X . n 
A 1 2   U 2   -301 ?  ? ? X . n 
A 1 3   A 3   -300 ?  ? ? X . n 
A 1 4   U 4   -299 ?  ? ? X . n 
A 1 5   G 5   -298 ?  ? ? X . n 
A 1 6   U 6   -297 ?  ? ? X . n 
A 1 7   G 7   -296 ?  ? ? X . n 
A 1 8   U 8   -295 ?  ? ? X . n 
A 1 9   G 9   -294 ?  ? ? X . n 
A 1 10  C 10  -293 ?  ? ? X . n 
A 1 11  C 11  -292 ?  ? ? X . n 
A 1 12  C 12  -291 ?  ? ? X . n 
A 1 13  G 13  -290 ?  ? ? X . n 
A 1 14  G 14  -289 ?  ? ? X . n 
A 1 15  C 15  -288 ?  ? ? X . n 
A 1 16  A 16  -287 ?  ? ? X . n 
A 1 17  U 17  -286 ?  ? ? X . n 
A 1 18  G 18  -285 ?  ? ? X . n 
A 1 19  G 19  -284 ?  ? ? X . n 
A 1 20  G 20  -283 ?  ? ? X . n 
A 1 21  U 21  -282 ?  ? ? X . n 
A 1 22  G 22  -281 ?  ? ? X . n 
A 1 23  C 23  -280 ?  ? ? X . n 
A 1 24  A 24  -279 ?  ? ? X . n 
A 1 25  G 25  -278 ?  ? ? X . n 
A 1 26  U 26  -277 ?  ? ? X . n 
A 1 27  C 27  -276 ?  ? ? X . n 
A 1 28  U 28  -275 ?  ? ? X . n 
A 1 29  A 29  -274 ?  ? ? X . n 
A 1 30  U 30  -273 ?  ? ? X . n 
A 1 31  A 31  -272 ?  ? ? X . n 
A 1 32  G 32  -271 ?  ? ? X . n 
A 1 33  G 33  -270 ?  ? ? X . n 
A 1 34  G 34  -269 ?  ? ? X . n 
A 1 35  U 35  -268 ?  ? ? X . n 
A 1 36  G 36  -267 ?  ? ? X . n 
A 1 37  A 37  -266 ?  ? ? X . n 
A 1 38  G 38  -265 ?  ? ? X . n 
A 1 39  A 39  -264 ?  ? ? X . n 
A 1 40  G 40  -263 ?  ? ? X . n 
A 1 41  U 41  -262 ?  ? ? X . n 
A 1 42  C 42  -261 ?  ? ? X . n 
A 1 43  C 43  -260 ?  ? ? X . n 
A 1 44  C 44  -259 ?  ? ? X . n 
A 1 45  G 45  -258 ?  ? ? X . n 
A 1 46  A 46  -257 ?  ? ? X . n 
A 1 47  A 47  -256 ?  ? ? X . n 
A 1 48  C 48  -255 ?  ? ? X . n 
A 1 49  U 49  -254 ?  ? ? X . n 
A 1 50  G 50  -253 ?  ? ? X . n 
A 1 51  U 51  -252 ?  ? ? X . n 
A 1 52  G 52  -251 ?  ? ? X . n 
A 1 53  A 53  -250 ?  ? ? X . n 
A 1 54  A 54  -249 ?  ? ? X . n 
A 1 55  G 55  -248 ?  ? ? X . n 
A 1 56  G 56  -247 ?  ? ? X . n 
A 1 57  C 57  -246 ?  ? ? X . n 
A 1 58  A 58  -245 ?  ? ? X . n 
A 1 59  G 59  -244 ?  ? ? X . n 
A 1 60  A 60  -243 ?  ? ? X . n 
A 1 61  A 61  -242 ?  ? ? X . n 
A 1 62  G 62  -241 ?  ? ? X . n 
A 1 63  U 63  -240 ?  ? ? X . n 
A 1 64  A 64  -239 ?  ? ? X . n 
A 1 65  A 65  -238 ?  ? ? X . n 
A 1 66  C 66  -237 ?  ? ? X . n 
A 1 67  A 67  -236 ?  ? ? X . n 
A 1 68  G 68  -235 ?  ? ? X . n 
A 1 69  U 69  -234 ?  ? ? X . n 
A 1 70  U 70  -233 ?  ? ? X . n 
A 1 71  A 71  -232 ?  ? ? X . n 
A 1 72  G 72  -231 ?  ? ? X . n 
A 1 73  C 73  -230 ?  ? ? X . n 
A 1 74  C 74  -229 ?  ? ? X . n 
A 1 75  U 75  -228 ?  ? ? X . n 
A 1 76  A 76  -227 ?  ? ? X . n 
A 1 77  A 77  -226 ?  ? ? X . n 
A 1 78  C 78  -225 ?  ? ? X . n 
A 1 79  G 79  -224 ?  ? ? X . n 
A 1 80  C 80  -223 ?  ? ? X . n 
A 1 81  A 81  -222 ?  ? ? X . n 
A 1 82  A 82  -221 ?  ? ? X . n 
A 1 83  G 83  -220 ?  ? ? X . n 
A 1 84  G 84  -219 ?  ? ? X . n 
A 1 85  G 85  -218 ?  ? ? X . n 
A 1 86  U 86  -217 ?  ? ? X . n 
A 1 87  G 87  -216 ?  ? ? X . n 
A 1 88  U 88  -215 ?  ? ? X . n 
A 1 89  C 89  -214 ?  ? ? X . n 
A 1 90  C 90  -213 ?  ? ? X . n 
A 1 91  G 91  -212 ?  ? ? X . n 
A 1 92  U 92  -211 ?  ? ? X . n 
A 1 93  G 93  -210 ?  ? ? X . n 
A 1 94  G 94  -209 ?  ? ? X . n 
A 1 95  C 95  -208 ?  ? ? X . n 
A 1 96  G 96  -207 ?  ? ? X . n 
A 1 97  A 97  -206 ?  ? ? X . n 
A 1 98  C 98  -205 ?  ? ? X . n 
A 1 99  A 99  -204 ?  ? ? X . n 
A 1 100 U 100 -203 ?  ? ? X . n 
A 1 101 G 101 -202 ?  ? ? X . n 
A 1 102 G 102 -201 ?  ? ? X . n 
A 1 103 A 103 -200 ?  ? ? X . n 
A 1 104 A 104 -199 ?  ? ? X . n 
A 1 105 U 105 -198 ?  ? ? X . n 
A 1 106 C 106 -197 ?  ? ? X . n 
A 1 107 U 107 -196 ?  ? ? X . n 
A 1 108 G 108 -195 ?  ? ? X . n 
A 1 109 A 109 -194 ?  ? ? X . n 
A 1 110 A 110 -193 ?  ? ? X . n 
A 1 111 G 111 -192 ?  ? ? X . n 
A 1 112 G 112 -191 ?  ? ? X . n 
A 1 113 A 113 -190 ?  ? ? X . n 
A 1 114 A 114 -189 ?  ? ? X . n 
A 1 115 G 115 -188 ?  ? ? X . n 
A 1 116 C 116 -187 ?  ? ? X . n 
A 1 117 G 117 -186 ?  ? ? X . n 
A 1 118 G 118 -185 ?  ? ? X . n 
A 1 119 A 119 -184 ?  ? ? X . n 
A 1 120 C 120 -183 ?  ? ? X . n 
A 1 121 G 121 -182 ?  ? ? X . n 
A 1 122 G 122 -181 ?  ? ? X . n 
A 1 123 C 123 -180 ?  ? ? X . n 
A 1 124 A 124 -179 ?  ? ? X . n 
A 1 125 A 125 -178 ?  ? ? X . n 
A 1 126 A 126 -177 ?  ? ? X . n 
A 1 127 C 127 -176 ?  ? ? X . n 
A 1 128 C 128 -175 ?  ? ? X . n 
A 1 129 U 129 -174 ?  ? ? X . n 
A 1 130 U 130 -173 ?  ? ? X . n 
A 1 131 C 131 -172 ?  ? ? X . n 
A 1 132 G 132 -171 ?  ? ? X . n 
A 1 133 G 133 -170 ?  ? ? X . n 
A 1 134 U 134 -169 ?  ? ? X . n 
A 1 135 C 135 -168 ?  ? ? X . n 
A 1 136 U 136 -167 ?  ? ? X . n 
A 1 137 G 137 -166 ?  ? ? X . n 
A 1 138 A 138 -165 ?  ? ? X . n 
A 1 139 G 139 -164 ?  ? ? X . n 
A 1 140 G 140 -163 ?  ? ? X . n 
A 1 141 A 141 -162 ?  ? ? X . n 
A 1 142 A 142 -161 ?  ? ? X . n 
A 1 143 C 143 -160 ?  ? ? X . n 
A 1 144 A 144 -159 ?  ? ? X . n 
A 1 145 C 145 -158 ?  ? ? X . n 
A 1 146 G 146 -157 ?  ? ? X . n 
A 1 147 A 147 -156 ?  ? ? X . n 
A 1 148 A 148 -155 ?  ? ? X . n 
A 1 149 C 149 -154 ?  ? ? X . n 
A 1 150 U 150 -153 ?  ? ? X . n 
A 1 151 U 151 -152 ?  ? ? X . n 
A 1 152 C 152 -151 ?  ? ? X . n 
A 1 153 A 153 -150 ?  ? ? X . n 
A 1 154 U 154 -149 ?  ? ? X . n 
A 1 155 A 155 -148 ?  ? ? X . n 
A 1 156 U 156 -147 ?  ? ? X . n 
A 1 157 G 157 -146 ?  ? ? X . n 
A 1 158 A 158 -145 ?  ? ? X . n 
A 1 159 G 159 -144 ?  ? ? X . n 
A 1 160 G 160 -143 ?  ? ? X . n 
A 1 161 C 161 -142 ?  ? ? X . n 
A 1 162 U 162 -141 ?  ? ? X . n 
A 1 163 A 163 -140 ?  ? ? X . n 
A 1 164 G 164 -139 ?  ? ? X . n 
A 1 165 G 165 -138 ?  ? ? X . n 
A 1 166 U 166 -137 ?  ? ? X . n 
A 1 167 A 167 -136 ?  ? ? X . n 
A 1 168 U 168 -135 ?  ? ? X . n 
A 1 169 C 169 -134 ?  ? ? X . n 
A 1 170 A 170 -133 ?  ? ? X . n 
A 1 171 A 171 -132 ?  ? ? X . n 
A 1 172 U 172 -131 ?  ? ? X . n 
A 1 173 G 173 -130 ?  ? ? X . n 
A 1 174 G 174 -129 ?  ? ? X . n 
A 1 175 A 175 -128 ?  ? ? X . n 
A 1 176 U 176 -127 ?  ? ? X . n 
A 1 177 G 177 -126 ?  ? ? X . n 
A 1 178 A 178 -125 ?  ? ? X . n 
A 1 179 G 179 -124 ?  ? ? X . n 
A 1 180 U 180 -123 ?  ? ? X . n 
A 1 181 U 181 -122 ?  ? ? X . n 
A 1 182 U 182 -121 ?  ? ? X . n 
A 1 183 G 183 -120 ?  ? ? X . n 
A 1 184 C 184 -119 ?  ? ? X . n 
A 1 185 A 185 -118 ?  ? ? X . n 
A 1 186 U 186 -117 ?  ? ? X . n 
A 1 187 A 187 -116 ?  ? ? X . n 
A 1 188 A 188 -115 ?  ? ? X . n 
A 1 189 C 189 -114 ?  ? ? X . n 
A 1 190 A 190 -113 ?  ? ? X . n 
A 1 191 A 191 -112 ?  ? ? X . n 
A 1 192 A 192 -111 ?  ? ? X . n 
A 1 193 A 193 -110 ?  ? ? X . n 
A 1 194 C 194 -109 ?  ? ? X . n 
A 1 195 A 195 -108 ?  ? ? X . n 
A 1 196 A 196 -107 ?  ? ? X . n 
A 1 197 A 197 -106 ?  ? ? X . n 
A 1 198 G 198 -105 ?  ? ? X . n 
A 1 199 U 199 -104 ?  ? ? X . n 
A 1 200 C 200 -103 ?  ? ? X . n 
A 1 201 C 201 -102 ?  ? ? X . n 
A 1 202 U 202 -101 ?  ? ? X . n 
A 1 203 U 203 -100 ?  ? ? X . n 
A 1 204 U 204 -99  ?  ? ? X . n 
A 1 205 C 205 -98  ?  ? ? X . n 
A 1 206 U 206 -97  ?  ? ? X . n 
A 1 207 G 207 -96  ?  ? ? X . n 
A 1 208 C 208 -95  ?  ? ? X . n 
A 1 209 C 209 -94  ?  ? ? X . n 
A 1 210 A 210 -93  ?  ? ? X . n 
A 1 211 A 211 -92  ?  ? ? X . n 
A 1 212 A 212 -91  ?  ? ? X . n 
A 1 213 G 213 -90  ?  ? ? X . n 
A 1 214 U 214 -89  ?  ? ? X . n 
A 1 215 U 215 -88  ?  ? ? X . n 
A 1 216 G 216 -87  ?  ? ? X . n 
A 1 217 G 217 -86  ?  ? ? X . n 
A 1 218 U 218 -85  ?  ? ? X . n 
A 1 219 A 219 -84  ?  ? ? X . n 
A 1 220 C 220 -83  ?  ? ? X . n 
A 1 221 A 221 -82  ?  ? ? X . n 
A 1 222 G 222 -81  ?  ? ? X . n 
A 1 223 A 223 -80  ?  ? ? X . n 
A 1 224 G 224 -79  ?  ? ? X . n 
A 1 225 U 225 -78  ?  ? ? X . n 
A 1 226 A 226 -77  ?  ? ? X . n 
A 1 227 A 227 -76  ?  ? ? X . n 
A 1 228 A 228 -75  ?  ? ? X . n 
A 1 229 U 229 -74  ?  ? ? X . n 
A 1 230 G 230 -73  ?  ? ? X . n 
A 1 231 A 231 -72  ?  ? ? X . n 
A 1 232 A 232 -71  ?  ? ? X . n 
A 1 233 G 233 -70  ?  ? ? X . n 
A 1 234 C 234 -69  ?  ? ? X . n 
A 1 235 A 235 -68  ?  ? ? X . n 
A 1 236 G 236 -67  ?  ? ? X . n 
A 1 237 A 237 -66  ?  ? ? X . n 
A 1 238 U 238 -65  ?  ? ? X . n 
A 1 239 U 239 -64  ?  ? ? X . n 
A 1 240 G 240 -63  ?  ? ? X . n 
A 1 241 A 241 -62  ?  ? ? X . n 
A 1 242 U 242 -61  ?  ? ? X . n 
A 1 243 G 243 -60  ?  ? ? X . n 
A 1 244 A 244 -59  ?  ? ? X . n 
A 1 245 A 245 -58  ?  ? ? X . n 
A 1 246 G 246 -57  ?  ? ? X . n 
A 1 247 G 247 -56  ?  ? ? X . n 
A 1 248 G 248 -55  ?  ? ? X . n 
A 1 249 A 249 -54  ?  ? ? X . n 
A 1 250 A 250 -53  ?  ? ? X . n 
A 1 251 A 251 -52  ?  ? ? X . n 
A 1 252 G 252 -51  ?  ? ? X . n 
A 1 253 A 253 -50  ?  ? ? X . n 
A 1 254 C 254 -49  ?  ? ? X . n 
A 1 255 U 255 -48  ?  ? ? X . n 
A 1 256 G 256 -47  ?  ? ? X . n 
A 1 257 C 257 -46  ?  ? ? X . n 
A 1 258 A 258 -45  ?  ? ? X . n 
A 1 259 U 259 -44  ?  ? ? X . n 
A 1 260 U 260 -43  ?  ? ? X . n 
A 1 261 C 261 -42  ?  ? ? X . n 
A 1 262 U 262 -41  ?  ? ? X . n 
A 1 263 U 263 -40  ?  ? ? X . n 
A 1 264 A 264 -39  ?  ? ? X . n 
A 1 265 C 265 -38  ?  ? ? X . n 
A 1 266 C 266 -37  ?  ? ? X . n 
A 1 267 C 267 -36  ?  ? ? X . n 
A 1 268 G 268 -35  ?  ? ? X . n 
A 1 269 G 269 -34  ?  ? ? X . n 
A 1 270 G 270 -33  ?  ? ? X . n 
A 1 271 G 271 -32  ?  ? ? X . n 
A 1 272 A 272 -31  ?  ? ? X . n 
A 1 273 G 273 -30  ?  ? ? X . n 
A 1 274 G 274 -29  ?  ? ? X . n 
A 1 275 U 275 -28  ?  ? ? X . n 
A 1 276 C 276 -27  ?  ? ? X . n 
A 1 277 U 277 -26  ?  ? ? X . n 
A 1 278 G 278 -25  ?  ? ? X . n 
A 1 279 G 279 -24  ?  ? ? X . n 
A 1 280 A 280 -23  ?  ? ? X . n 
A 1 281 A 281 -22  ?  ? ? X . n 
A 1 282 A 282 -21  ?  ? ? X . n 
A 1 283 C 283 -20  ?  ? ? X . n 
A 1 284 A 284 -19  ?  ? ? X . n 
A 1 285 G 285 -18  ?  ? ? X . n 
A 1 286 A 286 -17  ?  ? ? X . n 
A 1 287 A 287 -16  ?  ? ? X . n 
A 1 288 G 288 -15  ?  ? ? X . n 
A 1 289 U 289 -14  ?  ? ? X . n 
A 1 290 C 290 -13  ?  ? ? X . n 
A 1 291 A 291 -12  ?  ? ? X . n 
A 1 292 G 292 -11  ?  ? ? X . n 
A 1 293 C 293 -10  ?  ? ? X . n 
A 1 294 A 294 -9   ?  ? ? X . n 
A 1 295 G 295 -8   ?  ? ? X . n 
A 1 296 A 296 -7   ?  ? ? X . n 
A 1 297 A 297 -6   ?  ? ? X . n 
A 1 298 G 298 -5   ?  ? ? X . n 
A 1 299 U 299 -4   ?  ? ? X . n 
A 1 300 C 300 -3   ?  ? ? X . n 
A 1 301 A 301 -2   ?  ? ? X . n 
A 1 302 U 302 -1   ?  ? ? X . n 
A 1 303 A 303 0    ?  ? ? X . n 
A 1 304 G 304 1    ?  ? ? X . n 
A 1 305 U 305 2    ?  ? ? X . n 
A 1 306 A 306 3    ?  ? ? X . n 
A 1 307 C 307 4    ?  ? ? X . n 
A 1 308 C 308 5    ?  ? ? X . n 
A 1 309 C 309 6    ?  ? ? X . n 
A 1 310 U 310 7    ?  ? ? X . n 
A 1 311 C 311 8    ?  ? ? X . n 
A 1 312 A 312 9    ?  ? ? X . n 
A 1 313 G 313 10   10 G G X . n 
A 1 314 U 314 11   11 U U X . n 
A 1 315 A 315 12   12 A A X . n 
A 1 316 C 316 13   13 C C X . n 
A 1 317 U 317 14   14 U U X . n 
A 1 318 C 318 15   15 C C X . n 
A 1 319 G 319 16   16 G G X . n 
A 1 320 G 320 17   17 G G X . n 
A 1 321 G 321 18   18 G G X . n 
A 1 322 G 322 19   19 G G X . n 
A 1 323 U 323 20   20 U U X . n 
A 1 324 G 324 21   21 G G X . n 
A 1 325 C 325 22   22 C C X . n 
A 1 326 C 326 23   23 C C X . n 
A 1 327 C 327 24   24 C C X . n 
A 1 328 U 328 25   25 U U X . n 
A 1 329 U 329 26   26 U U X . n 
A 1 330 C 330 27   27 C C X . n 
A 1 331 U 331 28   28 U U X . n 
A 1 332 G 332 29   29 G G X . n 
A 1 333 C 333 30   30 C C X . n 
A 1 334 G 334 31   31 G G X . n 
A 1 335 U 335 32   32 U U X . n 
A 1 336 G 336 33   33 G G X . n 
A 1 337 A 337 34   34 A A X . n 
A 1 338 A 338 35   35 A A X . n 
A 1 339 G 339 36   36 G G X . n 
A 1 340 G 340 37   37 G G X . n 
A 1 341 C 341 38   38 C C X . n 
A 1 342 U 342 39   39 U U X . n 
A 1 343 G 343 40   40 G G X . n 
A 1 344 A 344 41   41 A A X . n 
A 1 345 G 345 42   42 G G X . n 
A 1 346 A 346 43   43 A A X . n 
A 1 347 A 347 44   44 A A X . n 
A 1 348 A 348 45   45 A A X . n 
A 1 349 U 349 46   46 U U X . n 
A 1 350 A 350 47   47 A A X . n 
A 1 351 C 351 48   48 C C X . n 
A 1 352 C 352 49   49 C C X . n 
A 1 353 C 353 50   50 C C X . n 
A 1 354 G 354 51   51 G G X . n 
A 1 355 U 355 52   52 U U X . n 
A 1 356 A 356 53   53 A A X . n 
A 1 357 U 357 54   54 U U X . n 
A 1 358 C 358 55   55 C C X . n 
A 1 359 A 359 56   56 A A X . n 
A 1 360 C 360 57   57 C C X . n 
A 1 361 C 361 58   58 C C X . n 
A 1 362 U 362 59   59 U U X . n 
A 1 363 G 363 60   60 G G X . n 
A 1 364 A 364 61   61 A A X . n 
A 1 365 U 365 62   62 U U X . n 
A 1 366 C 366 63   63 C C X . n 
A 1 367 U 367 64   64 U U X . n 
A 1 368 G 368 65   65 G G X . n 
A 1 369 G 369 66   66 G G X . n 
A 1 370 A 370 67   67 A A X . n 
A 1 371 U 371 68   68 U U X . n 
A 1 372 A 372 69   69 A A X . n 
A 1 373 A 373 70   70 A A X . n 
A 1 374 U 374 71   71 U U X . n 
A 1 375 G 375 72   72 G G X . n 
A 1 376 C 376 73   73 C C X . n 
A 1 377 C 377 74   74 C C X . n 
A 1 378 A 378 75   75 A A X . n 
A 1 379 G 379 76   76 G G X . n 
A 1 380 C 380 77   77 C C X . n 
A 1 381 G 381 78   78 G G X . n 
A 1 382 U 382 79   79 U U X . n 
A 1 383 A 383 80   80 A A X . n 
A 1 384 G 384 81   81 G G X . n 
A 1 385 G 385 82   82 G G X . n 
A 1 386 G 386 83   83 G G X . n 
A 1 387 A 387 84   84 A A X . n 
A 1 388 A 388 85   85 A A X . n 
A 1 389 G 389 86   86 G G X . n 
A 1 390 U 390 87   87 U U X . n 
A 1 391 G 391 88   88 G G X . n 
A 1 392 C 392 89   89 C C X . n 
A 1 393 U 393 90   ?  ? ? X . n 
A 1 394 G 394 91   ?  ? ? X . n 
A 1 395 A 395 92   ?  ? ? X . n 
A 1 396 G 396 93   ?  ? ? X . n 
A 1 397 G 397 94   ?  ? ? X . n 
A 1 398 G 398 95   ?  ? ? X . n 
A 1 399 G 399 96   ?  ? ? X . n 
A 1 400 A 400 97   ?  ? ? X . n 
A 1 401 A 401 98   ?  ? ? X . n 
A 1 402 G 402 99   ?  ? ? X . n 
A 1 403 G 403 100  ?  ? ? X . n 
A 1 404 A 404 101  ?  ? ? X . n 
A 1 405 C 405 102  ?  ? ? X . n 
A 1 406 G 406 103  ?  ? ? X . n 
A 1 407 G 407 104  ?  ? ? X . n 
A 1 408 A 408 105  ?  ? ? X . n 
A 1 409 A 409 106  ?  ? ? X . n 
A 1 410 C 410 107  ?  ? ? X . n 
A 1 411 A 411 108  ?  ? ? X . n 
A 1 412 A 412 109  ?  ? ? X . n 
A 1 413 G 413 110  ?  ? ? X . n 
A 1 414 U 414 111  ?  ? ? X . n 
A 1 415 A 415 112  ?  ? ? X . n 
A 1 416 U 416 113  ?  ? ? X . n 
A 1 417 G 417 114  ?  ? ? X . n 
A 1 418 G 418 115  ?  ? ? X . n 
A 1 419 C 419 116  ?  ? ? X . n 
A 1 420 G 420 117  ?  ? ? X . n 
A 1 421 U 421 118  ?  ? ? X . n 
A 1 422 U 422 119  ?  ? ? X . n 
A 1 423 C 423 120  ?  ? ? X . n 
A 1 424 G 424 121  ?  ? ? X . n 
A 1 425 C 425 122  ?  ? ? X . n 
A 1 426 G 426 123  ?  ? ? X . n 
A 1 427 C 427 124  ?  ? ? X . n 
A 1 428 C 428 125  ?  ? ? X . n 
A 1 429 U 429 126  ?  ? ? X . n 
A 1 430 A 430 127  ?  ? ? X . n 
A 1 431 A 431 128  ?  ? ? X . n 
A 1 432 G 432 129  ?  ? ? X . n 
A 1 433 C 433 130  ?  ? ? X . n 
A 1 434 U 434 131  ?  ? ? X . n 
A 1 435 U 435 132  ?  ? ? X . n 
A 1 436 G 436 133  ?  ? ? X . n 
A 1 437 A 437 134  ?  ? ? X . n 
A 1 438 A 438 135  ?  ? ? X . n 
A 1 439 C 439 136  ?  ? ? X . n 
A 1 440 C 440 137  ?  ? ? X . n 
A 1 441 A 441 138  ?  ? ? X . n 
A 1 442 C 442 139  ?  ? ? X . n 
A 1 443 C 443 140  ?  ? ? X . n 
A 1 444 G 444 141  ?  ? ? X . n 
A 1 445 U 445 142  ?  ? ? X . n 
A 1 446 A 446 143  ?  ? ? X . n 
A 1 447 U 447 144  ?  ? ? X . n 
A 1 448 A 448 145  ?  ? ? X . n 
A 1 449 C 449 146  ?  ? ? X . n 
A 1 450 C 450 147  ?  ? ? X . n 
A 1 451 G 451 148  ?  ? ? X . n 
A 1 452 A 452 149  ?  ? ? X . n 
A 1 453 A 453 150  ?  ? ? X . n 
A 1 454 C 454 151  ?  ? ? X . n 
A 1 455 G 455 152  ?  ? ? X . n 
A 1 456 G 456 153  ?  ? ? X . n 
A 1 457 U 457 154  ?  ? ? X . n 
A 1 458 A 458 155  ?  ? ? X . n 
A 1 459 C 459 156  ?  ? ? X . n 
A 1 460 G 460 157  ?  ? ? X . n 
A 1 461 U 461 158  ?  ? ? X . n 
A 1 462 A 462 159  ?  ? ? X . n 
A 1 463 C 463 160  ?  ? ? X . n 
A 1 464 G 464 161  ?  ? ? X . n 
A 1 465 G 465 162  ?  ? ? X . n 
A 1 466 U 466 163  ?  ? ? X . n 
A 1 467 G 467 164  ?  ? ? X . n 
A 1 468 G 468 165  ?  ? ? X . n 
A 1 469 U 469 166  ?  ? ? X . n 
A 1 470 G 470 167  ?  ? ? X . n 
A 1 471 U 471 168  ?  ? ? X . n 
A 1 472 G 472 169  ?  ? ? X . n 
A 1 473 A 473 170  ?  ? ? X . n 
A 1 474 G 474 171  ?  ? ? X . n 
A 1 475 A 475 172  ?  ? ? X . n 
A 1 476 G 476 173  ?  ? ? X . n 
A 1 477 G 477 174  ?  ? ? X . n 
A 1 478 A 478 175  ?  ? ? X . n 
A 1 479 G 479 176  ?  ? ? X . n 
A 1 480 U 480 177  ?  ? ? X . n 
A 1 481 U 481 178  ?  ? ? X . n 
A 1 482 C 482 179  ?  ? ? X . n 
A 1 483 G 483 180  ?  ? ? X . n 
A 1 484 C 484 181  ?  ? ? X . n 
A 1 485 U 485 182  ?  ? ? X . n 
A 1 486 C 486 183  ?  ? ? X . n 
A 1 487 U 487 184  ?  ? ? X . n 
A 1 488 A 488 185  ?  ? ? X . n 
A 1 489 C 489 186  ?  ? ? X . n 
A 1 490 U 490 187  ?  ? ? X . n 
A 1 491 C 491 188  ?  ? ? X . n 
A 1 492 U 492 189  ?  ? ? X . n 
A 1 493 A 493 190  ?  ? ? X . n 
A 1 494 U 494 191  ?  ? ? X . n 
A 1 495 U 495 192  ?  ? ? X . n 
A 1 496 A 496 193  ?  ? ? X . n 
A 1 497 G 497 194  ?  ? ? X . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 MG  1 201 101 MG  MG  X . 
C 2 MG  1 202 102 MG  MG  X . 
D 3 TPP 1 203 100 TPP TPP X . 
E 2 MG  1 204 1   MG  MG  X . 
F 2 MG  1 205 2   MG  MG  X . 
G 2 MG  1 206 3   MG  MG  X . 
H 2 MG  1 207 4   MG  MG  X . 
I 4 NA  1 208 1   NA  NA  X . 
J 4 NA  1 209 2   NA  NA  X . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9C6K 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9C6K 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9C6K 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9C6K 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.008  ? 1941 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.756  ? 3023 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 18.889 ? 963  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.044  ? 400  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005  ? 82   ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9C6K 
_struct.title                        
'Cryo-EM structure of the TPP riboswitch embedded in an RNA scaffold bound to thiamine pyrophosphate' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9C6K 
_struct_keywords.text            'RNA, Riboswitch, Ligand' 
_struct_keywords.pdbx_keywords   RNA 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 3 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
I N N 4 ? 
J N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9C6K 
_struct_ref.pdbx_db_accession          9C6K 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9C6K 
_struct_ref_seq.pdbx_strand_id                X 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 497 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             9C6K 
_struct_ref_seq.db_align_beg                  -302 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  194 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       -302 
_struct_ref_seq.pdbx_auth_seq_align_end       194 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A U   328 O4 ? ? ? 1_555 J NA  .   NA  ? ? X U   25  X NA  209 1_555 ? ? ? ? ? ? ?                    2.342 ? 
? 
metalc2  metalc ? ? A G   363 O6 ? ? ? 1_555 B MG  .   MG  ? ? X G   60  X MG  201 1_555 ? ? ? ? ? ? ?                    1.990 ? 
? 
metalc3  metalc ? ? A G   381 O6 ? ? ? 1_555 B MG  .   MG  ? ? X G   78  X MG  201 1_555 ? ? ? ? ? ? ?                    1.919 ? 
? 
metalc4  metalc ? ? B MG  .   MG ? ? ? 1_555 D TPP .   O2B ? ? X MG  201 X TPP 203 1_555 ? ? ? ? ? ? ?                    1.888 ? 
? 
metalc5  metalc ? ? C MG  .   MG ? ? ? 1_555 D TPP .   O1A ? ? X MG  202 X TPP 203 1_555 ? ? ? ? ? ? ?                    2.075 ? 
? 
metalc6  metalc ? ? C MG  .   MG ? ? ? 1_555 D TPP .   O1B ? ? X MG  202 X TPP 203 1_555 ? ? ? ? ? ? ?                    2.794 ? 
? 
metalc7  metalc ? ? D TPP .   O7 ? ? ? 1_555 E MG  .   MG  ? ? X TPP 203 X MG  204 1_555 ? ? ? ? ? ? ?                    2.933 ? 
? 
hydrog1  hydrog ? ? A G   313 N1 ? ? ? 1_555 A C   392 N3  ? ? X G   10  X C   89  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog2  hydrog ? ? A G   313 N2 ? ? ? 1_555 A C   392 O2  ? ? X G   10  X C   89  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog3  hydrog ? ? A G   313 O6 ? ? ? 1_555 A C   392 N4  ? ? X G   10  X C   89  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog4  hydrog ? ? A U   314 N3 ? ? ? 1_555 A G   391 O6  ? ? X U   11  X G   88  1_555 ? ? ? ? ? ? TYPE_28_PAIR         ?     ? 
? 
hydrog5  hydrog ? ? A U   314 O2 ? ? ? 1_555 A G   391 N1  ? ? X U   11  X G   88  1_555 ? ? ? ? ? ? TYPE_28_PAIR         ?     ? 
? 
hydrog6  hydrog ? ? A A   315 N1 ? ? ? 1_555 A U   390 N3  ? ? X A   12  X U   87  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog7  hydrog ? ? A A   315 N6 ? ? ? 1_555 A U   390 O4  ? ? X A   12  X U   87  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog8  hydrog ? ? A C   316 N3 ? ? ? 1_555 A G   389 N1  ? ? X C   13  X G   86  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog9  hydrog ? ? A C   316 N4 ? ? ? 1_555 A G   389 O6  ? ? X C   13  X G   86  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog10 hydrog ? ? A C   316 O2 ? ? ? 1_555 A G   389 N2  ? ? X C   13  X G   86  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog11 hydrog ? ? A U   317 N3 ? ? ? 1_555 A A   388 N1  ? ? X U   14  X A   85  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog12 hydrog ? ? A U   317 O4 ? ? ? 1_555 A A   388 N6  ? ? X U   14  X A   85  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog13 hydrog ? ? A C   318 N3 ? ? ? 1_555 A G   354 N1  ? ? X C   15  X G   51  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog14 hydrog ? ? A C   318 N4 ? ? ? 1_555 A G   354 O6  ? ? X C   15  X G   51  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog15 hydrog ? ? A C   318 O2 ? ? ? 1_555 A G   354 N2  ? ? X C   15  X G   51  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog16 hydrog ? ? A G   319 N1 ? ? ? 1_555 A C   353 N3  ? ? X G   16  X C   50  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog17 hydrog ? ? A G   319 N2 ? ? ? 1_555 A C   353 O2  ? ? X G   16  X C   50  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog18 hydrog ? ? A G   319 O6 ? ? ? 1_555 A C   353 N4  ? ? X G   16  X C   50  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog19 hydrog ? ? A G   319 N2 ? ? ? 1_555 A A   387 N3  ? ? X G   16  X A   84  1_555 ? ? ? ? ? ? 'G-A MISPAIR'        ?     ? 
? 
hydrog20 hydrog ? ? A G   320 N1 ? ? ? 1_555 A C   352 N3  ? ? X G   17  X C   49  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog21 hydrog ? ? A G   320 N2 ? ? ? 1_555 A C   352 O2  ? ? X G   17  X C   49  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog22 hydrog ? ? A G   320 O6 ? ? ? 1_555 A C   352 N4  ? ? X G   17  X C   49  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog23 hydrog ? ? A G   320 N2 ? ? ? 1_555 A A   359 N3  ? ? X G   17  X A   56  1_555 ? ? ? ? ? ? 'G-A MISPAIR'        ?     ? 
? 
hydrog24 hydrog ? ? A G   321 N1 ? ? ? 1_555 A C   351 N3  ? ? X G   18  X C   48  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog25 hydrog ? ? A G   321 N2 ? ? ? 1_555 A C   351 O2  ? ? X G   18  X C   48  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog26 hydrog ? ? A G   321 O6 ? ? ? 1_555 A C   351 N4  ? ? X G   18  X C   48  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog27 hydrog ? ? A G   322 N2 ? ? ? 1_555 A G   345 N3  ? ? X G   19  X G   42  1_555 ? ? ? ? ? ? TYPE_4_PAIR          ?     ? 
? 
hydrog28 hydrog ? ? A G   322 N3 ? ? ? 1_555 A G   345 N2  ? ? X G   19  X G   42  1_555 ? ? ? ? ? ? TYPE_4_PAIR          ?     ? 
? 
hydrog29 hydrog ? ? A G   322 N1 ? ? ? 1_555 A A   350 N1  ? ? X G   19  X A   47  1_555 ? ? ? ? ? ? TYPE_8_PAIR          ?     ? 
? 
hydrog30 hydrog ? ? A G   322 O6 ? ? ? 1_555 A A   350 N6  ? ? X G   19  X A   47  1_555 ? ? ? ? ? ? TYPE_8_PAIR          ?     ? 
? 
hydrog31 hydrog ? ? A U   323 N3 ? ? ? 1_555 A A   348 N1  ? ? X U   20  X A   45  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog32 hydrog ? ? A U   323 O4 ? ? ? 1_555 A A   348 N6  ? ? X U   20  X A   45  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog33 hydrog ? ? A G   324 N1 ? ? ? 1_555 A C   341 N3  ? ? X G   21  X C   38  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog34 hydrog ? ? A G   324 N2 ? ? ? 1_555 A C   341 O2  ? ? X G   21  X C   38  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog35 hydrog ? ? A G   324 O6 ? ? ? 1_555 A C   341 N4  ? ? X G   21  X C   38  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog36 hydrog ? ? A C   325 N3 ? ? ? 1_555 A G   340 N1  ? ? X C   22  X G   37  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog37 hydrog ? ? A C   325 N4 ? ? ? 1_555 A G   340 O6  ? ? X C   22  X G   37  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog38 hydrog ? ? A C   325 O2 ? ? ? 1_555 A G   340 N2  ? ? X C   22  X G   37  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog39 hydrog ? ? A C   326 N3 ? ? ? 1_555 A G   339 N1  ? ? X C   23  X G   36  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog40 hydrog ? ? A C   326 N4 ? ? ? 1_555 A G   339 O6  ? ? X C   23  X G   36  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog41 hydrog ? ? A C   326 O2 ? ? ? 1_555 A G   339 N2  ? ? X C   23  X G   36  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog42 hydrog ? ? A U   328 N3 ? ? ? 1_555 A A   338 N1  ? ? X U   25  X A   35  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog43 hydrog ? ? A U   328 O4 ? ? ? 1_555 A A   338 N6  ? ? X U   25  X A   35  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog44 hydrog ? ? A U   329 N3 ? ? ? 1_555 A A   337 N1  ? ? X U   26  X A   34  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog45 hydrog ? ? A U   329 O4 ? ? ? 1_555 A A   337 N6  ? ? X U   26  X A   34  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog46 hydrog ? ? A C   330 N3 ? ? ? 1_555 A G   336 N1  ? ? X C   27  X G   33  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog47 hydrog ? ? A C   330 N4 ? ? ? 1_555 A G   336 O6  ? ? X C   27  X G   33  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog48 hydrog ? ? A C   330 O2 ? ? ? 1_555 A G   336 N2  ? ? X C   27  X G   33  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog49 hydrog ? ? A U   331 N3 ? ? ? 1_555 A U   335 O4  ? ? X U   28  X U   32  1_555 ? ? ? ? ? ? TYPE_12_PAIR         ?     ? 
? 
hydrog50 hydrog ? ? A U   331 O4 ? ? ? 1_555 A U   335 N3  ? ? X U   28  X U   32  1_555 ? ? ? ? ? ? TYPE_12_PAIR         ?     ? 
? 
hydrog51 hydrog ? ? A G   340 N2 ? ? ? 1_555 A A   372 N1  ? ? X G   37  X A   69  1_555 ? ? ? ? ? ? 'G-A MISPAIR'        ?     ? 
? 
hydrog52 hydrog ? ? A U   342 N3 ? ? ? 1_555 A A   346 N7  ? ? X U   39  X A   43  1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN' ?     ? 
? 
hydrog53 hydrog ? ? A U   342 O2 ? ? ? 1_555 A A   346 N6  ? ? X U   39  X A   43  1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN' ?     ? 
? 
hydrog54 hydrog ? ? A A   356 N6 ? ? ? 1_555 A A   387 N7  ? ? X A   53  X A   84  1_555 ? ? ? ? ? ? TYPE_2_PAIR          ?     ? 
? 
hydrog55 hydrog ? ? A A   356 N7 ? ? ? 1_555 A A   387 N6  ? ? X A   53  X A   84  1_555 ? ? ? ? ? ? TYPE_2_PAIR          ?     ? 
? 
hydrog56 hydrog ? ? A A   359 N6 ? ? ? 1_555 A G   386 N3  ? ? X A   56  X G   83  1_555 ? ? ? ? ? ? TYPE_11_PAIR         ?     ? 
? 
hydrog57 hydrog ? ? A A   359 N7 ? ? ? 1_555 A G   386 N2  ? ? X A   56  X G   83  1_555 ? ? ? ? ? ? TYPE_11_PAIR         ?     ? 
? 
hydrog58 hydrog ? ? A C   360 N3 ? ? ? 1_555 A G   385 N1  ? ? X C   57  X G   82  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog59 hydrog ? ? A C   360 N4 ? ? ? 1_555 A G   385 O6  ? ? X C   57  X G   82  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog60 hydrog ? ? A C   360 O2 ? ? ? 1_555 A G   385 N2  ? ? X C   57  X G   82  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog61 hydrog ? ? A C   361 N3 ? ? ? 1_555 A G   384 N1  ? ? X C   58  X G   81  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog62 hydrog ? ? A C   361 N4 ? ? ? 1_555 A G   384 O6  ? ? X C   58  X G   81  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog63 hydrog ? ? A C   361 O2 ? ? ? 1_555 A G   384 N2  ? ? X C   58  X G   81  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog64 hydrog ? ? A U   362 N3 ? ? ? 1_555 A A   383 N1  ? ? X U   59  X A   80  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog65 hydrog ? ? A U   362 O4 ? ? ? 1_555 A A   383 N6  ? ? X U   59  X A   80  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog66 hydrog ? ? A G   363 N1 ? ? ? 1_555 A G   381 O6  ? ? X G   60  X G   78  1_555 ? ? ? ? ? ? TYPE_6_PAIR          ?     ? 
? 
hydrog67 hydrog ? ? A G   363 N2 ? ? ? 1_555 A G   381 N7  ? ? X G   60  X G   78  1_555 ? ? ? ? ? ? TYPE_6_PAIR          ?     ? 
? 
hydrog68 hydrog ? ? A A   364 N6 ? ? ? 1_555 A C   380 O2  ? ? X A   61  X C   77  1_555 ? ? ? ? ? ? 'A-C MISPAIR'        ?     ? 
? 
hydrog69 hydrog ? ? A C   366 N3 ? ? ? 1_555 A G   379 N1  ? ? X C   63  X G   76  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog70 hydrog ? ? A C   366 N4 ? ? ? 1_555 A G   379 O6  ? ? X C   63  X G   76  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog71 hydrog ? ? A C   366 O2 ? ? ? 1_555 A G   379 N2  ? ? X C   63  X G   76  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog72 hydrog ? ? A U   367 N3 ? ? ? 1_555 A A   378 N1  ? ? X U   64  X A   75  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog73 hydrog ? ? A U   367 O4 ? ? ? 1_555 A A   378 N6  ? ? X U   64  X A   75  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog74 hydrog ? ? A G   368 N1 ? ? ? 1_555 A C   377 N3  ? ? X G   65  X C   74  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog75 hydrog ? ? A G   368 N2 ? ? ? 1_555 A C   377 O2  ? ? X G   65  X C   74  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog76 hydrog ? ? A G   368 O6 ? ? ? 1_555 A C   377 N4  ? ? X G   65  X C   74  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog77 hydrog ? ? A G   369 N1 ? ? ? 1_555 A C   376 N3  ? ? X G   66  X C   73  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog78 hydrog ? ? A G   369 N2 ? ? ? 1_555 A C   376 O2  ? ? X G   66  X C   73  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
hydrog79 hydrog ? ? A G   369 O6 ? ? ? 1_555 A C   376 N4  ? ? X G   66  X C   73  1_555 ? ? ? ? ? ? WATSON-CRICK         ?     ? 
? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
metalc ? ? 
hydrog ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 O6  ? A G   363 ? X G   60  ? 1_555 MG ? B MG . ? X MG 201 ? 1_555 O6  ? A G   381 ? X G   78  ? 1_555 86.4  ? 
2 O6  ? A G   363 ? X G   60  ? 1_555 MG ? B MG . ? X MG 201 ? 1_555 O2B ? D TPP .   ? X TPP 203 ? 1_555 148.1 ? 
3 O6  ? A G   381 ? X G   78  ? 1_555 MG ? B MG . ? X MG 201 ? 1_555 O2B ? D TPP .   ? X TPP 203 ? 1_555 99.2  ? 
4 O1A ? D TPP .   ? X TPP 203 ? 1_555 MG ? C MG . ? X MG 202 ? 1_555 O1B ? D TPP .   ? X TPP 203 ? 1_555 72.5  ? 
# 
_pdbx_entry_details.entry_id                   9C6K 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9C6K 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9C6K 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.94 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               655558 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            6.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'TPP riboswitch embedded in an RNA scaffold bound with thiamine pyrophosphate' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9C6K 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'SPOT SCAN' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9C6K 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE-PROPANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9C6K 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 X U -302 ? A U 1   
2   1 Y 1 X U -301 ? A U 2   
3   1 Y 1 X A -300 ? A A 3   
4   1 Y 1 X U -299 ? A U 4   
5   1 Y 1 X G -298 ? A G 5   
6   1 Y 1 X U -297 ? A U 6   
7   1 Y 1 X G -296 ? A G 7   
8   1 Y 1 X U -295 ? A U 8   
9   1 Y 1 X G -294 ? A G 9   
10  1 Y 1 X C -293 ? A C 10  
11  1 Y 1 X C -292 ? A C 11  
12  1 Y 1 X C -291 ? A C 12  
13  1 Y 1 X G -290 ? A G 13  
14  1 Y 1 X G -289 ? A G 14  
15  1 Y 1 X C -288 ? A C 15  
16  1 Y 1 X A -287 ? A A 16  
17  1 Y 1 X U -286 ? A U 17  
18  1 Y 1 X G -285 ? A G 18  
19  1 Y 1 X G -284 ? A G 19  
20  1 Y 1 X G -283 ? A G 20  
21  1 Y 1 X U -282 ? A U 21  
22  1 Y 1 X G -281 ? A G 22  
23  1 Y 1 X C -280 ? A C 23  
24  1 Y 1 X A -279 ? A A 24  
25  1 Y 1 X G -278 ? A G 25  
26  1 Y 1 X U -277 ? A U 26  
27  1 Y 1 X C -276 ? A C 27  
28  1 Y 1 X U -275 ? A U 28  
29  1 Y 1 X A -274 ? A A 29  
30  1 Y 1 X U -273 ? A U 30  
31  1 Y 1 X A -272 ? A A 31  
32  1 Y 1 X G -271 ? A G 32  
33  1 Y 1 X G -270 ? A G 33  
34  1 Y 1 X G -269 ? A G 34  
35  1 Y 1 X U -268 ? A U 35  
36  1 Y 1 X G -267 ? A G 36  
37  1 Y 1 X A -266 ? A A 37  
38  1 Y 1 X G -265 ? A G 38  
39  1 Y 1 X A -264 ? A A 39  
40  1 Y 1 X G -263 ? A G 40  
41  1 Y 1 X U -262 ? A U 41  
42  1 Y 1 X C -261 ? A C 42  
43  1 Y 1 X C -260 ? A C 43  
44  1 Y 1 X C -259 ? A C 44  
45  1 Y 1 X G -258 ? A G 45  
46  1 Y 1 X A -257 ? A A 46  
47  1 Y 1 X A -256 ? A A 47  
48  1 Y 1 X C -255 ? A C 48  
49  1 Y 1 X U -254 ? A U 49  
50  1 Y 1 X G -253 ? A G 50  
51  1 Y 1 X U -252 ? A U 51  
52  1 Y 1 X G -251 ? A G 52  
53  1 Y 1 X A -250 ? A A 53  
54  1 Y 1 X A -249 ? A A 54  
55  1 Y 1 X G -248 ? A G 55  
56  1 Y 1 X G -247 ? A G 56  
57  1 Y 1 X C -246 ? A C 57  
58  1 Y 1 X A -245 ? A A 58  
59  1 Y 1 X G -244 ? A G 59  
60  1 Y 1 X A -243 ? A A 60  
61  1 Y 1 X A -242 ? A A 61  
62  1 Y 1 X G -241 ? A G 62  
63  1 Y 1 X U -240 ? A U 63  
64  1 Y 1 X A -239 ? A A 64  
65  1 Y 1 X A -238 ? A A 65  
66  1 Y 1 X C -237 ? A C 66  
67  1 Y 1 X A -236 ? A A 67  
68  1 Y 1 X G -235 ? A G 68  
69  1 Y 1 X U -234 ? A U 69  
70  1 Y 1 X U -233 ? A U 70  
71  1 Y 1 X A -232 ? A A 71  
72  1 Y 1 X G -231 ? A G 72  
73  1 Y 1 X C -230 ? A C 73  
74  1 Y 1 X C -229 ? A C 74  
75  1 Y 1 X U -228 ? A U 75  
76  1 Y 1 X A -227 ? A A 76  
77  1 Y 1 X A -226 ? A A 77  
78  1 Y 1 X C -225 ? A C 78  
79  1 Y 1 X G -224 ? A G 79  
80  1 Y 1 X C -223 ? A C 80  
81  1 Y 1 X A -222 ? A A 81  
82  1 Y 1 X A -221 ? A A 82  
83  1 Y 1 X G -220 ? A G 83  
84  1 Y 1 X G -219 ? A G 84  
85  1 Y 1 X G -218 ? A G 85  
86  1 Y 1 X U -217 ? A U 86  
87  1 Y 1 X G -216 ? A G 87  
88  1 Y 1 X U -215 ? A U 88  
89  1 Y 1 X C -214 ? A C 89  
90  1 Y 1 X C -213 ? A C 90  
91  1 Y 1 X G -212 ? A G 91  
92  1 Y 1 X U -211 ? A U 92  
93  1 Y 1 X G -210 ? A G 93  
94  1 Y 1 X G -209 ? A G 94  
95  1 Y 1 X C -208 ? A C 95  
96  1 Y 1 X G -207 ? A G 96  
97  1 Y 1 X A -206 ? A A 97  
98  1 Y 1 X C -205 ? A C 98  
99  1 Y 1 X A -204 ? A A 99  
100 1 Y 1 X U -203 ? A U 100 
101 1 Y 1 X G -202 ? A G 101 
102 1 Y 1 X G -201 ? A G 102 
103 1 Y 1 X A -200 ? A A 103 
104 1 Y 1 X A -199 ? A A 104 
105 1 Y 1 X U -198 ? A U 105 
106 1 Y 1 X C -197 ? A C 106 
107 1 Y 1 X U -196 ? A U 107 
108 1 Y 1 X G -195 ? A G 108 
109 1 Y 1 X A -194 ? A A 109 
110 1 Y 1 X A -193 ? A A 110 
111 1 Y 1 X G -192 ? A G 111 
112 1 Y 1 X G -191 ? A G 112 
113 1 Y 1 X A -190 ? A A 113 
114 1 Y 1 X A -189 ? A A 114 
115 1 Y 1 X G -188 ? A G 115 
116 1 Y 1 X C -187 ? A C 116 
117 1 Y 1 X G -186 ? A G 117 
118 1 Y 1 X G -185 ? A G 118 
119 1 Y 1 X A -184 ? A A 119 
120 1 Y 1 X C -183 ? A C 120 
121 1 Y 1 X G -182 ? A G 121 
122 1 Y 1 X G -181 ? A G 122 
123 1 Y 1 X C -180 ? A C 123 
124 1 Y 1 X A -179 ? A A 124 
125 1 Y 1 X A -178 ? A A 125 
126 1 Y 1 X A -177 ? A A 126 
127 1 Y 1 X C -176 ? A C 127 
128 1 Y 1 X C -175 ? A C 128 
129 1 Y 1 X U -174 ? A U 129 
130 1 Y 1 X U -173 ? A U 130 
131 1 Y 1 X C -172 ? A C 131 
132 1 Y 1 X G -171 ? A G 132 
133 1 Y 1 X G -170 ? A G 133 
134 1 Y 1 X U -169 ? A U 134 
135 1 Y 1 X C -168 ? A C 135 
136 1 Y 1 X U -167 ? A U 136 
137 1 Y 1 X G -166 ? A G 137 
138 1 Y 1 X A -165 ? A A 138 
139 1 Y 1 X G -164 ? A G 139 
140 1 Y 1 X G -163 ? A G 140 
141 1 Y 1 X A -162 ? A A 141 
142 1 Y 1 X A -161 ? A A 142 
143 1 Y 1 X C -160 ? A C 143 
144 1 Y 1 X A -159 ? A A 144 
145 1 Y 1 X C -158 ? A C 145 
146 1 Y 1 X G -157 ? A G 146 
147 1 Y 1 X A -156 ? A A 147 
148 1 Y 1 X A -155 ? A A 148 
149 1 Y 1 X C -154 ? A C 149 
150 1 Y 1 X U -153 ? A U 150 
151 1 Y 1 X U -152 ? A U 151 
152 1 Y 1 X C -151 ? A C 152 
153 1 Y 1 X A -150 ? A A 153 
154 1 Y 1 X U -149 ? A U 154 
155 1 Y 1 X A -148 ? A A 155 
156 1 Y 1 X U -147 ? A U 156 
157 1 Y 1 X G -146 ? A G 157 
158 1 Y 1 X A -145 ? A A 158 
159 1 Y 1 X G -144 ? A G 159 
160 1 Y 1 X G -143 ? A G 160 
161 1 Y 1 X C -142 ? A C 161 
162 1 Y 1 X U -141 ? A U 162 
163 1 Y 1 X A -140 ? A A 163 
164 1 Y 1 X G -139 ? A G 164 
165 1 Y 1 X G -138 ? A G 165 
166 1 Y 1 X U -137 ? A U 166 
167 1 Y 1 X A -136 ? A A 167 
168 1 Y 1 X U -135 ? A U 168 
169 1 Y 1 X C -134 ? A C 169 
170 1 Y 1 X A -133 ? A A 170 
171 1 Y 1 X A -132 ? A A 171 
172 1 Y 1 X U -131 ? A U 172 
173 1 Y 1 X G -130 ? A G 173 
174 1 Y 1 X G -129 ? A G 174 
175 1 Y 1 X A -128 ? A A 175 
176 1 Y 1 X U -127 ? A U 176 
177 1 Y 1 X G -126 ? A G 177 
178 1 Y 1 X A -125 ? A A 178 
179 1 Y 1 X G -124 ? A G 179 
180 1 Y 1 X U -123 ? A U 180 
181 1 Y 1 X U -122 ? A U 181 
182 1 Y 1 X U -121 ? A U 182 
183 1 Y 1 X G -120 ? A G 183 
184 1 Y 1 X C -119 ? A C 184 
185 1 Y 1 X A -118 ? A A 185 
186 1 Y 1 X U -117 ? A U 186 
187 1 Y 1 X A -116 ? A A 187 
188 1 Y 1 X A -115 ? A A 188 
189 1 Y 1 X C -114 ? A C 189 
190 1 Y 1 X A -113 ? A A 190 
191 1 Y 1 X A -112 ? A A 191 
192 1 Y 1 X A -111 ? A A 192 
193 1 Y 1 X A -110 ? A A 193 
194 1 Y 1 X C -109 ? A C 194 
195 1 Y 1 X A -108 ? A A 195 
196 1 Y 1 X A -107 ? A A 196 
197 1 Y 1 X A -106 ? A A 197 
198 1 Y 1 X G -105 ? A G 198 
199 1 Y 1 X U -104 ? A U 199 
200 1 Y 1 X C -103 ? A C 200 
201 1 Y 1 X C -102 ? A C 201 
202 1 Y 1 X U -101 ? A U 202 
203 1 Y 1 X U -100 ? A U 203 
204 1 Y 1 X U -99  ? A U 204 
205 1 Y 1 X C -98  ? A C 205 
206 1 Y 1 X U -97  ? A U 206 
207 1 Y 1 X G -96  ? A G 207 
208 1 Y 1 X C -95  ? A C 208 
209 1 Y 1 X C -94  ? A C 209 
210 1 Y 1 X A -93  ? A A 210 
211 1 Y 1 X A -92  ? A A 211 
212 1 Y 1 X A -91  ? A A 212 
213 1 Y 1 X G -90  ? A G 213 
214 1 Y 1 X U -89  ? A U 214 
215 1 Y 1 X U -88  ? A U 215 
216 1 Y 1 X G -87  ? A G 216 
217 1 Y 1 X G -86  ? A G 217 
218 1 Y 1 X U -85  ? A U 218 
219 1 Y 1 X A -84  ? A A 219 
220 1 Y 1 X C -83  ? A C 220 
221 1 Y 1 X A -82  ? A A 221 
222 1 Y 1 X G -81  ? A G 222 
223 1 Y 1 X A -80  ? A A 223 
224 1 Y 1 X G -79  ? A G 224 
225 1 Y 1 X U -78  ? A U 225 
226 1 Y 1 X A -77  ? A A 226 
227 1 Y 1 X A -76  ? A A 227 
228 1 Y 1 X A -75  ? A A 228 
229 1 Y 1 X U -74  ? A U 229 
230 1 Y 1 X G -73  ? A G 230 
231 1 Y 1 X A -72  ? A A 231 
232 1 Y 1 X A -71  ? A A 232 
233 1 Y 1 X G -70  ? A G 233 
234 1 Y 1 X C -69  ? A C 234 
235 1 Y 1 X A -68  ? A A 235 
236 1 Y 1 X G -67  ? A G 236 
237 1 Y 1 X A -66  ? A A 237 
238 1 Y 1 X U -65  ? A U 238 
239 1 Y 1 X U -64  ? A U 239 
240 1 Y 1 X G -63  ? A G 240 
241 1 Y 1 X A -62  ? A A 241 
242 1 Y 1 X U -61  ? A U 242 
243 1 Y 1 X G -60  ? A G 243 
244 1 Y 1 X A -59  ? A A 244 
245 1 Y 1 X A -58  ? A A 245 
246 1 Y 1 X G -57  ? A G 246 
247 1 Y 1 X G -56  ? A G 247 
248 1 Y 1 X G -55  ? A G 248 
249 1 Y 1 X A -54  ? A A 249 
250 1 Y 1 X A -53  ? A A 250 
251 1 Y 1 X A -52  ? A A 251 
252 1 Y 1 X G -51  ? A G 252 
253 1 Y 1 X A -50  ? A A 253 
254 1 Y 1 X C -49  ? A C 254 
255 1 Y 1 X U -48  ? A U 255 
256 1 Y 1 X G -47  ? A G 256 
257 1 Y 1 X C -46  ? A C 257 
258 1 Y 1 X A -45  ? A A 258 
259 1 Y 1 X U -44  ? A U 259 
260 1 Y 1 X U -43  ? A U 260 
261 1 Y 1 X C -42  ? A C 261 
262 1 Y 1 X U -41  ? A U 262 
263 1 Y 1 X U -40  ? A U 263 
264 1 Y 1 X A -39  ? A A 264 
265 1 Y 1 X C -38  ? A C 265 
266 1 Y 1 X C -37  ? A C 266 
267 1 Y 1 X C -36  ? A C 267 
268 1 Y 1 X G -35  ? A G 268 
269 1 Y 1 X G -34  ? A G 269 
270 1 Y 1 X G -33  ? A G 270 
271 1 Y 1 X G -32  ? A G 271 
272 1 Y 1 X A -31  ? A A 272 
273 1 Y 1 X G -30  ? A G 273 
274 1 Y 1 X G -29  ? A G 274 
275 1 Y 1 X U -28  ? A U 275 
276 1 Y 1 X C -27  ? A C 276 
277 1 Y 1 X U -26  ? A U 277 
278 1 Y 1 X G -25  ? A G 278 
279 1 Y 1 X G -24  ? A G 279 
280 1 Y 1 X A -23  ? A A 280 
281 1 Y 1 X A -22  ? A A 281 
282 1 Y 1 X A -21  ? A A 282 
283 1 Y 1 X C -20  ? A C 283 
284 1 Y 1 X A -19  ? A A 284 
285 1 Y 1 X G -18  ? A G 285 
286 1 Y 1 X A -17  ? A A 286 
287 1 Y 1 X A -16  ? A A 287 
288 1 Y 1 X G -15  ? A G 288 
289 1 Y 1 X U -14  ? A U 289 
290 1 Y 1 X C -13  ? A C 290 
291 1 Y 1 X A -12  ? A A 291 
292 1 Y 1 X G -11  ? A G 292 
293 1 Y 1 X C -10  ? A C 293 
294 1 Y 1 X A -9   ? A A 294 
295 1 Y 1 X G -8   ? A G 295 
296 1 Y 1 X A -7   ? A A 296 
297 1 Y 1 X A -6   ? A A 297 
298 1 Y 1 X G -5   ? A G 298 
299 1 Y 1 X U -4   ? A U 299 
300 1 Y 1 X C -3   ? A C 300 
301 1 Y 1 X A -2   ? A A 301 
302 1 Y 1 X U -1   ? A U 302 
303 1 Y 1 X A 0    ? A A 303 
304 1 Y 1 X G 1    ? A G 304 
305 1 Y 1 X U 2    ? A U 305 
306 1 Y 1 X A 3    ? A A 306 
307 1 Y 1 X C 4    ? A C 307 
308 1 Y 1 X C 5    ? A C 308 
309 1 Y 1 X C 6    ? A C 309 
310 1 Y 1 X U 7    ? A U 310 
311 1 Y 1 X C 8    ? A C 311 
312 1 Y 1 X A 9    ? A A 312 
313 1 Y 1 X U 90   ? A U 393 
314 1 Y 1 X G 91   ? A G 394 
315 1 Y 1 X A 92   ? A A 395 
316 1 Y 1 X G 93   ? A G 396 
317 1 Y 1 X G 94   ? A G 397 
318 1 Y 1 X G 95   ? A G 398 
319 1 Y 1 X G 96   ? A G 399 
320 1 Y 1 X A 97   ? A A 400 
321 1 Y 1 X A 98   ? A A 401 
322 1 Y 1 X G 99   ? A G 402 
323 1 Y 1 X G 100  ? A G 403 
324 1 Y 1 X A 101  ? A A 404 
325 1 Y 1 X C 102  ? A C 405 
326 1 Y 1 X G 103  ? A G 406 
327 1 Y 1 X G 104  ? A G 407 
328 1 Y 1 X A 105  ? A A 408 
329 1 Y 1 X A 106  ? A A 409 
330 1 Y 1 X C 107  ? A C 410 
331 1 Y 1 X A 108  ? A A 411 
332 1 Y 1 X A 109  ? A A 412 
333 1 Y 1 X G 110  ? A G 413 
334 1 Y 1 X U 111  ? A U 414 
335 1 Y 1 X A 112  ? A A 415 
336 1 Y 1 X U 113  ? A U 416 
337 1 Y 1 X G 114  ? A G 417 
338 1 Y 1 X G 115  ? A G 418 
339 1 Y 1 X C 116  ? A C 419 
340 1 Y 1 X G 117  ? A G 420 
341 1 Y 1 X U 118  ? A U 421 
342 1 Y 1 X U 119  ? A U 422 
343 1 Y 1 X C 120  ? A C 423 
344 1 Y 1 X G 121  ? A G 424 
345 1 Y 1 X C 122  ? A C 425 
346 1 Y 1 X G 123  ? A G 426 
347 1 Y 1 X C 124  ? A C 427 
348 1 Y 1 X C 125  ? A C 428 
349 1 Y 1 X U 126  ? A U 429 
350 1 Y 1 X A 127  ? A A 430 
351 1 Y 1 X A 128  ? A A 431 
352 1 Y 1 X G 129  ? A G 432 
353 1 Y 1 X C 130  ? A C 433 
354 1 Y 1 X U 131  ? A U 434 
355 1 Y 1 X U 132  ? A U 435 
356 1 Y 1 X G 133  ? A G 436 
357 1 Y 1 X A 134  ? A A 437 
358 1 Y 1 X A 135  ? A A 438 
359 1 Y 1 X C 136  ? A C 439 
360 1 Y 1 X C 137  ? A C 440 
361 1 Y 1 X A 138  ? A A 441 
362 1 Y 1 X C 139  ? A C 442 
363 1 Y 1 X C 140  ? A C 443 
364 1 Y 1 X G 141  ? A G 444 
365 1 Y 1 X U 142  ? A U 445 
366 1 Y 1 X A 143  ? A A 446 
367 1 Y 1 X U 144  ? A U 447 
368 1 Y 1 X A 145  ? A A 448 
369 1 Y 1 X C 146  ? A C 449 
370 1 Y 1 X C 147  ? A C 450 
371 1 Y 1 X G 148  ? A G 451 
372 1 Y 1 X A 149  ? A A 452 
373 1 Y 1 X A 150  ? A A 453 
374 1 Y 1 X C 151  ? A C 454 
375 1 Y 1 X G 152  ? A G 455 
376 1 Y 1 X G 153  ? A G 456 
377 1 Y 1 X U 154  ? A U 457 
378 1 Y 1 X A 155  ? A A 458 
379 1 Y 1 X C 156  ? A C 459 
380 1 Y 1 X G 157  ? A G 460 
381 1 Y 1 X U 158  ? A U 461 
382 1 Y 1 X A 159  ? A A 462 
383 1 Y 1 X C 160  ? A C 463 
384 1 Y 1 X G 161  ? A G 464 
385 1 Y 1 X G 162  ? A G 465 
386 1 Y 1 X U 163  ? A U 466 
387 1 Y 1 X G 164  ? A G 467 
388 1 Y 1 X G 165  ? A G 468 
389 1 Y 1 X U 166  ? A U 469 
390 1 Y 1 X G 167  ? A G 470 
391 1 Y 1 X U 168  ? A U 471 
392 1 Y 1 X G 169  ? A G 472 
393 1 Y 1 X A 170  ? A A 473 
394 1 Y 1 X G 171  ? A G 474 
395 1 Y 1 X A 172  ? A A 475 
396 1 Y 1 X G 173  ? A G 476 
397 1 Y 1 X G 174  ? A G 477 
398 1 Y 1 X A 175  ? A A 478 
399 1 Y 1 X G 176  ? A G 479 
400 1 Y 1 X U 177  ? A U 480 
401 1 Y 1 X U 178  ? A U 481 
402 1 Y 1 X C 179  ? A C 482 
403 1 Y 1 X G 180  ? A G 483 
404 1 Y 1 X C 181  ? A C 484 
405 1 Y 1 X U 182  ? A U 485 
406 1 Y 1 X C 183  ? A C 486 
407 1 Y 1 X U 184  ? A U 487 
408 1 Y 1 X A 185  ? A A 488 
409 1 Y 1 X C 186  ? A C 489 
410 1 Y 1 X U 187  ? A U 490 
411 1 Y 1 X C 188  ? A C 491 
412 1 Y 1 X U 189  ? A U 492 
413 1 Y 1 X A 190  ? A A 493 
414 1 Y 1 X U 191  ? A U 494 
415 1 Y 1 X U 192  ? A U 495 
416 1 Y 1 X A 193  ? A A 496 
417 1 Y 1 X G 194  ? A G 497 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A   OP3    O  N N 1   
A   P      P  N N 2   
A   OP1    O  N N 3   
A   OP2    O  N N 4   
A   "O5'"  O  N N 5   
A   "C5'"  C  N N 6   
A   "C4'"  C  N R 7   
A   "O4'"  O  N N 8   
A   "C3'"  C  N S 9   
A   "O3'"  O  N N 10  
A   "C2'"  C  N R 11  
A   "O2'"  O  N N 12  
A   "C1'"  C  N R 13  
A   N9     N  Y N 14  
A   C8     C  Y N 15  
A   N7     N  Y N 16  
A   C5     C  Y N 17  
A   C6     C  Y N 18  
A   N6     N  N N 19  
A   N1     N  Y N 20  
A   C2     C  Y N 21  
A   N3     N  Y N 22  
A   C4     C  Y N 23  
A   HOP3   H  N N 24  
A   HOP2   H  N N 25  
A   "H5'"  H  N N 26  
A   "H5''" H  N N 27  
A   "H4'"  H  N N 28  
A   "H3'"  H  N N 29  
A   "HO3'" H  N N 30  
A   "H2'"  H  N N 31  
A   "HO2'" H  N N 32  
A   "H1'"  H  N N 33  
A   H8     H  N N 34  
A   H61    H  N N 35  
A   H62    H  N N 36  
A   H2     H  N N 37  
C   OP3    O  N N 38  
C   P      P  N N 39  
C   OP1    O  N N 40  
C   OP2    O  N N 41  
C   "O5'"  O  N N 42  
C   "C5'"  C  N N 43  
C   "C4'"  C  N R 44  
C   "O4'"  O  N N 45  
C   "C3'"  C  N S 46  
C   "O3'"  O  N N 47  
C   "C2'"  C  N R 48  
C   "O2'"  O  N N 49  
C   "C1'"  C  N R 50  
C   N1     N  N N 51  
C   C2     C  N N 52  
C   O2     O  N N 53  
C   N3     N  N N 54  
C   C4     C  N N 55  
C   N4     N  N N 56  
C   C5     C  N N 57  
C   C6     C  N N 58  
C   HOP3   H  N N 59  
C   HOP2   H  N N 60  
C   "H5'"  H  N N 61  
C   "H5''" H  N N 62  
C   "H4'"  H  N N 63  
C   "H3'"  H  N N 64  
C   "HO3'" H  N N 65  
C   "H2'"  H  N N 66  
C   "HO2'" H  N N 67  
C   "H1'"  H  N N 68  
C   H41    H  N N 69  
C   H42    H  N N 70  
C   H5     H  N N 71  
C   H6     H  N N 72  
G   OP3    O  N N 73  
G   P      P  N N 74  
G   OP1    O  N N 75  
G   OP2    O  N N 76  
G   "O5'"  O  N N 77  
G   "C5'"  C  N N 78  
G   "C4'"  C  N R 79  
G   "O4'"  O  N N 80  
G   "C3'"  C  N S 81  
G   "O3'"  O  N N 82  
G   "C2'"  C  N R 83  
G   "O2'"  O  N N 84  
G   "C1'"  C  N R 85  
G   N9     N  Y N 86  
G   C8     C  Y N 87  
G   N7     N  Y N 88  
G   C5     C  Y N 89  
G   C6     C  N N 90  
G   O6     O  N N 91  
G   N1     N  N N 92  
G   C2     C  N N 93  
G   N2     N  N N 94  
G   N3     N  N N 95  
G   C4     C  Y N 96  
G   HOP3   H  N N 97  
G   HOP2   H  N N 98  
G   "H5'"  H  N N 99  
G   "H5''" H  N N 100 
G   "H4'"  H  N N 101 
G   "H3'"  H  N N 102 
G   "HO3'" H  N N 103 
G   "H2'"  H  N N 104 
G   "HO2'" H  N N 105 
G   "H1'"  H  N N 106 
G   H8     H  N N 107 
G   H1     H  N N 108 
G   H21    H  N N 109 
G   H22    H  N N 110 
MG  MG     MG N N 111 
NA  NA     NA N N 112 
TPP "N1'"  N  Y N 113 
TPP "C2'"  C  Y N 114 
TPP CM2    C  N N 115 
TPP "N3'"  N  Y N 116 
TPP "C4'"  C  Y N 117 
TPP "N4'"  N  N N 118 
TPP "C5'"  C  Y N 119 
TPP "C6'"  C  Y N 120 
TPP "C7'"  C  N N 121 
TPP N3     N  Y N 122 
TPP C2     C  Y N 123 
TPP S1     S  Y N 124 
TPP C5     C  Y N 125 
TPP C4     C  Y N 126 
TPP CM4    C  N N 127 
TPP C6     C  N N 128 
TPP C7     C  N N 129 
TPP O7     O  N N 130 
TPP PA     P  N S 131 
TPP O1A    O  N N 132 
TPP O2A    O  N N 133 
TPP O3A    O  N N 134 
TPP PB     P  N N 135 
TPP O1B    O  N N 136 
TPP O2B    O  N N 137 
TPP O3B    O  N N 138 
TPP HM21   H  N N 139 
TPP HM22   H  N N 140 
TPP HM23   H  N N 141 
TPP HN41   H  N N 142 
TPP HN42   H  N N 143 
TPP "H6'"  H  N N 144 
TPP "H7'1" H  N N 145 
TPP "H7'2" H  N N 146 
TPP H2     H  N N 147 
TPP HM41   H  N N 148 
TPP HM42   H  N N 149 
TPP HM43   H  N N 150 
TPP H61    H  N N 151 
TPP H62    H  N N 152 
TPP H71    H  N N 153 
TPP H72    H  N N 154 
TPP HOA2   H  N N 155 
TPP HOB2   H  N N 156 
TPP HOB3   H  N N 157 
U   OP3    O  N N 158 
U   P      P  N N 159 
U   OP1    O  N N 160 
U   OP2    O  N N 161 
U   "O5'"  O  N N 162 
U   "C5'"  C  N N 163 
U   "C4'"  C  N R 164 
U   "O4'"  O  N N 165 
U   "C3'"  C  N S 166 
U   "O3'"  O  N N 167 
U   "C2'"  C  N R 168 
U   "O2'"  O  N N 169 
U   "C1'"  C  N R 170 
U   N1     N  N N 171 
U   C2     C  N N 172 
U   O2     O  N N 173 
U   N3     N  N N 174 
U   C4     C  N N 175 
U   O4     O  N N 176 
U   C5     C  N N 177 
U   C6     C  N N 178 
U   HOP3   H  N N 179 
U   HOP2   H  N N 180 
U   "H5'"  H  N N 181 
U   "H5''" H  N N 182 
U   "H4'"  H  N N 183 
U   "H3'"  H  N N 184 
U   "HO3'" H  N N 185 
U   "H2'"  H  N N 186 
U   "HO2'" H  N N 187 
U   "H1'"  H  N N 188 
U   H3     H  N N 189 
U   H5     H  N N 190 
U   H6     H  N N 191 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A   OP3   P      sing N N 1   
A   OP3   HOP3   sing N N 2   
A   P     OP1    doub N N 3   
A   P     OP2    sing N N 4   
A   P     "O5'"  sing N N 5   
A   OP2   HOP2   sing N N 6   
A   "O5'" "C5'"  sing N N 7   
A   "C5'" "C4'"  sing N N 8   
A   "C5'" "H5'"  sing N N 9   
A   "C5'" "H5''" sing N N 10  
A   "C4'" "O4'"  sing N N 11  
A   "C4'" "C3'"  sing N N 12  
A   "C4'" "H4'"  sing N N 13  
A   "O4'" "C1'"  sing N N 14  
A   "C3'" "O3'"  sing N N 15  
A   "C3'" "C2'"  sing N N 16  
A   "C3'" "H3'"  sing N N 17  
A   "O3'" "HO3'" sing N N 18  
A   "C2'" "O2'"  sing N N 19  
A   "C2'" "C1'"  sing N N 20  
A   "C2'" "H2'"  sing N N 21  
A   "O2'" "HO2'" sing N N 22  
A   "C1'" N9     sing N N 23  
A   "C1'" "H1'"  sing N N 24  
A   N9    C8     sing Y N 25  
A   N9    C4     sing Y N 26  
A   C8    N7     doub Y N 27  
A   C8    H8     sing N N 28  
A   N7    C5     sing Y N 29  
A   C5    C6     sing Y N 30  
A   C5    C4     doub Y N 31  
A   C6    N6     sing N N 32  
A   C6    N1     doub Y N 33  
A   N6    H61    sing N N 34  
A   N6    H62    sing N N 35  
A   N1    C2     sing Y N 36  
A   C2    N3     doub Y N 37  
A   C2    H2     sing N N 38  
A   N3    C4     sing Y N 39  
C   OP3   P      sing N N 40  
C   OP3   HOP3   sing N N 41  
C   P     OP1    doub N N 42  
C   P     OP2    sing N N 43  
C   P     "O5'"  sing N N 44  
C   OP2   HOP2   sing N N 45  
C   "O5'" "C5'"  sing N N 46  
C   "C5'" "C4'"  sing N N 47  
C   "C5'" "H5'"  sing N N 48  
C   "C5'" "H5''" sing N N 49  
C   "C4'" "O4'"  sing N N 50  
C   "C4'" "C3'"  sing N N 51  
C   "C4'" "H4'"  sing N N 52  
C   "O4'" "C1'"  sing N N 53  
C   "C3'" "O3'"  sing N N 54  
C   "C3'" "C2'"  sing N N 55  
C   "C3'" "H3'"  sing N N 56  
C   "O3'" "HO3'" sing N N 57  
C   "C2'" "O2'"  sing N N 58  
C   "C2'" "C1'"  sing N N 59  
C   "C2'" "H2'"  sing N N 60  
C   "O2'" "HO2'" sing N N 61  
C   "C1'" N1     sing N N 62  
C   "C1'" "H1'"  sing N N 63  
C   N1    C2     sing N N 64  
C   N1    C6     sing N N 65  
C   C2    O2     doub N N 66  
C   C2    N3     sing N N 67  
C   N3    C4     doub N N 68  
C   C4    N4     sing N N 69  
C   C4    C5     sing N N 70  
C   N4    H41    sing N N 71  
C   N4    H42    sing N N 72  
C   C5    C6     doub N N 73  
C   C5    H5     sing N N 74  
C   C6    H6     sing N N 75  
G   OP3   P      sing N N 76  
G   OP3   HOP3   sing N N 77  
G   P     OP1    doub N N 78  
G   P     OP2    sing N N 79  
G   P     "O5'"  sing N N 80  
G   OP2   HOP2   sing N N 81  
G   "O5'" "C5'"  sing N N 82  
G   "C5'" "C4'"  sing N N 83  
G   "C5'" "H5'"  sing N N 84  
G   "C5'" "H5''" sing N N 85  
G   "C4'" "O4'"  sing N N 86  
G   "C4'" "C3'"  sing N N 87  
G   "C4'" "H4'"  sing N N 88  
G   "O4'" "C1'"  sing N N 89  
G   "C3'" "O3'"  sing N N 90  
G   "C3'" "C2'"  sing N N 91  
G   "C3'" "H3'"  sing N N 92  
G   "O3'" "HO3'" sing N N 93  
G   "C2'" "O2'"  sing N N 94  
G   "C2'" "C1'"  sing N N 95  
G   "C2'" "H2'"  sing N N 96  
G   "O2'" "HO2'" sing N N 97  
G   "C1'" N9     sing N N 98  
G   "C1'" "H1'"  sing N N 99  
G   N9    C8     sing Y N 100 
G   N9    C4     sing Y N 101 
G   C8    N7     doub Y N 102 
G   C8    H8     sing N N 103 
G   N7    C5     sing Y N 104 
G   C5    C6     sing N N 105 
G   C5    C4     doub Y N 106 
G   C6    O6     doub N N 107 
G   C6    N1     sing N N 108 
G   N1    C2     sing N N 109 
G   N1    H1     sing N N 110 
G   C2    N2     sing N N 111 
G   C2    N3     doub N N 112 
G   N2    H21    sing N N 113 
G   N2    H22    sing N N 114 
G   N3    C4     sing N N 115 
TPP "N1'" "C2'"  doub Y N 116 
TPP "N1'" "C6'"  sing Y N 117 
TPP "C2'" CM2    sing N N 118 
TPP "C2'" "N3'"  sing Y N 119 
TPP CM2   HM21   sing N N 120 
TPP CM2   HM22   sing N N 121 
TPP CM2   HM23   sing N N 122 
TPP "N3'" "C4'"  doub Y N 123 
TPP "C4'" "N4'"  sing N N 124 
TPP "C4'" "C5'"  sing Y N 125 
TPP "N4'" HN41   sing N N 126 
TPP "N4'" HN42   sing N N 127 
TPP "C5'" "C6'"  doub Y N 128 
TPP "C5'" "C7'"  sing N N 129 
TPP "C6'" "H6'"  sing N N 130 
TPP "C7'" N3     sing N N 131 
TPP "C7'" "H7'1" sing N N 132 
TPP "C7'" "H7'2" sing N N 133 
TPP N3    C2     doub Y N 134 
TPP N3    C4     sing Y N 135 
TPP C2    S1     sing Y N 136 
TPP C2    H2     sing N N 137 
TPP S1    C5     sing Y N 138 
TPP C5    C4     doub Y N 139 
TPP C5    C6     sing N N 140 
TPP C4    CM4    sing N N 141 
TPP CM4   HM41   sing N N 142 
TPP CM4   HM42   sing N N 143 
TPP CM4   HM43   sing N N 144 
TPP C6    C7     sing N N 145 
TPP C6    H61    sing N N 146 
TPP C6    H62    sing N N 147 
TPP C7    O7     sing N N 148 
TPP C7    H71    sing N N 149 
TPP C7    H72    sing N N 150 
TPP O7    PA     sing N N 151 
TPP PA    O1A    doub N N 152 
TPP PA    O2A    sing N N 153 
TPP PA    O3A    sing N N 154 
TPP O2A   HOA2   sing N N 155 
TPP O3A   PB     sing N N 156 
TPP PB    O1B    doub N N 157 
TPP PB    O2B    sing N N 158 
TPP PB    O3B    sing N N 159 
TPP O2B   HOB2   sing N N 160 
TPP O3B   HOB3   sing N N 161 
U   OP3   P      sing N N 162 
U   OP3   HOP3   sing N N 163 
U   P     OP1    doub N N 164 
U   P     OP2    sing N N 165 
U   P     "O5'"  sing N N 166 
U   OP2   HOP2   sing N N 167 
U   "O5'" "C5'"  sing N N 168 
U   "C5'" "C4'"  sing N N 169 
U   "C5'" "H5'"  sing N N 170 
U   "C5'" "H5''" sing N N 171 
U   "C4'" "O4'"  sing N N 172 
U   "C4'" "C3'"  sing N N 173 
U   "C4'" "H4'"  sing N N 174 
U   "O4'" "C1'"  sing N N 175 
U   "C3'" "O3'"  sing N N 176 
U   "C3'" "C2'"  sing N N 177 
U   "C3'" "H3'"  sing N N 178 
U   "O3'" "HO3'" sing N N 179 
U   "C2'" "O2'"  sing N N 180 
U   "C2'" "C1'"  sing N N 181 
U   "C2'" "H2'"  sing N N 182 
U   "O2'" "HO2'" sing N N 183 
U   "C1'" N1     sing N N 184 
U   "C1'" "H1'"  sing N N 185 
U   N1    C2     sing N N 186 
U   N1    C6     sing N N 187 
U   C2    O2     doub N N 188 
U   C2    N3     sing N N 189 
U   N3    C4     sing N N 190 
U   N3    H3     sing N N 191 
U   C4    O4     doub N N 192 
U   C4    C5     sing N N 193 
U   C5    C6     doub N N 194 
U   C5    H5     sing N N 195 
U   C6    H6     sing N N 196 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-06-07 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9C6K 
_em_admin.last_update        2025-02-05 
_em_admin.map_release_date   2024-12-04 
_em_admin.title              'Cryo-EM structure of the TPP riboswitch embedded in an RNA scaffold bound to thiamine pyrophosphate' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                .027 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          562 
_em_entity_assembly_naturalsource.organism             'Escherichia coli' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
9C6K 'double helix'         
9C6K 'a-form double helix'  
9C6K 'hairpin loop'         
9C6K 'bulge loop'           
9C6K 'mismatched base pair' 
9C6K 'internal loop'        
9C6K 'three-way junction'   
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 A G 313 1_555 A C 392 1_555 -0.138 -0.369 -1.058 -1.932  5.434   -4.488   1  X_G10:C89_X X 10 ? X 89 ? 19 1  
1 A U 314 1_555 A G 391 1_555 1.695  -0.436 -0.147 0.535   1.379   0.096    2  X_U11:G88_X X 11 ? X 88 ? 28 1  
1 A A 315 1_555 A U 390 1_555 0.087  -0.265 0.762  2.511   -8.727  -10.147  3  X_A12:U87_X X 12 ? X 87 ? 20 1  
1 A C 316 1_555 A G 389 1_555 0.214  -0.328 0.786  2.086   -8.517  -5.165   4  X_C13:G86_X X 13 ? X 86 ? 19 1  
1 A U 317 1_555 A A 388 1_555 -0.025 -0.231 0.568  -3.076  -4.830  5.754    5  X_U14:A85_X X 14 ? X 85 ? 20 1  
1 A C 318 1_555 A G 354 1_555 0.148  -0.233 0.688  2.513   -3.452  0.655    6  X_C15:G51_X X 15 ? X 51 ? 19 1  
1 A G 319 1_555 A C 353 1_555 -0.263 -0.104 -0.188 -2.589  -10.418 4.247    7  X_G16:C50_X X 16 ? X 50 ? 19 1  
1 A G 320 1_555 A C 352 1_555 -0.207 -0.124 -0.272 -11.555 -7.250  -0.283   8  X_G17:C49_X X 17 ? X 49 ? 19 1  
1 A G 321 1_555 A C 351 1_555 -0.219 -0.174 -0.471 -5.160  -4.038  1.286    9  X_G18:C48_X X 18 ? X 48 ? 19 1  
1 A G 322 1_555 A A 350 1_555 -0.055 1.358  -0.607 0.644   -0.200  -26.455  10 X_G19:A47_X X 19 ? X 47 ? 8  1  
1 A U 323 1_555 A A 348 1_555 0.159  -0.138 0.285  8.499   5.853   5.382    11 X_U20:A45_X X 20 ? X 45 ? 20 1  
1 A U 335 1_555 A U 331 1_555 2.048  0.450  -1.672 -15.448 -48.660 166.598  12 X_U32:U28_X X 32 ? X 28 ? 12 2  
1 A G 336 1_555 A C 330 1_555 -0.208 -0.227 -0.358 0.000   1.543   -2.419   13 X_G33:C27_X X 33 ? X 27 ? 19 1  
1 A A 337 1_555 A U 329 1_555 0.067  -0.404 -1.216 2.940   1.801   0.395    14 X_A34:U26_X X 34 ? X 26 ? 20 1  
1 A A 338 1_555 A U 328 1_555 -0.086 -0.097 0.461  -7.571  7.595   12.225   15 X_A35:U25_X X 35 ? X 25 ? 20 1  
1 A G 339 1_555 A C 326 1_555 -0.114 -0.130 -0.267 -15.190 10.843  1.834    16 X_G36:C23_X X 36 ? X 23 ? 19 1  
1 A G 340 1_555 A C 325 1_555 -0.201 -0.174 0.415  -6.292  4.375   2.346    17 X_G37:C22_X X 37 ? X 22 ? 19 1  
1 A C 341 1_555 A G 324 1_555 0.227  -0.278 0.657  -7.592  10.287  -1.296   18 X_C38:G21_X X 38 ? X 21 ? 19 1  
1 A U 342 1_555 A A 346 1_555 3.851  -1.604 0.342  4.246   11.668  -102.762 19 X_U39:A43_X X 39 ? X 43 ? 24 4  
1 A A 356 1_555 A A 387 1_555 -4.659 5.170  -0.125 19.037  -6.439  -173.272 20 X_A53:A84_X X 53 ? X 84 ? 2  7  
1 A A 359 1_555 A G 386 1_555 -6.614 -4.079 -0.477 4.941   -5.256  -8.760   21 X_A56:G83_X X 56 ? X 83 ? 11 10 
1 A C 360 1_555 A G 385 1_555 0.210  -0.286 0.439  4.172   -5.005  -0.137   22 X_C57:G82_X X 57 ? X 82 ? 19 1  
1 A C 361 1_555 A G 384 1_555 0.221  -0.268 0.259  -1.032  -11.415 -1.407   23 X_C58:G81_X X 58 ? X 81 ? 19 1  
1 A U 362 1_555 A A 383 1_555 -0.101 -0.068 0.060  -5.230  -6.164  -3.849   24 X_U59:A80_X X 59 ? X 80 ? 20 1  
1 A G 363 1_555 A G 381 1_555 0.990  3.047  -0.456 -20.774 4.453   -95.220  25 X_G60:G78_X X 60 ? X 78 ? 6  3  
1 A A 364 1_555 A C 380 1_555 -1.930 1.836  1.965  10.126  1.683   99.726   26 X_A61:C77_X X 61 ? X 77 ? ?  ?  
1 A C 366 1_555 A G 379 1_555 0.137  -0.177 -0.595 3.961   -1.533  1.773    27 X_C63:G76_X X 63 ? X 76 ? 19 1  
1 A U 367 1_555 A A 378 1_555 -0.137 -0.115 -0.561 3.334   4.624   -0.562   28 X_U64:A75_X X 64 ? X 75 ? 20 1  
1 A G 368 1_555 A C 377 1_555 -0.181 -0.092 -0.378 -8.058  0.736   0.851    29 X_G65:C74_X X 65 ? X 74 ? 19 1  
1 A G 369 1_555 A C 376 1_555 -0.202 -0.174 -0.337 3.204   1.514   1.273    30 X_G66:C73_X X 66 ? X 73 ? 19 1  
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 A G 313 1_555 A C 392 1_555 A U 314 1_555 A G 391 1_555 0.482  -1.433 3.570  -1.995  -0.543   41.279  -1.967 -0.916 3.561 -0.769 
2.828   41.329   1  XX_G10U11:G88C89_XX X 10 ? X 89 ? X 11 ? X 88 ? 
1 A U 314 1_555 A G 391 1_555 A A 315 1_555 A U 390 1_555 -0.774 -1.996 2.447  -2.155  29.594   36.329  -3.906 0.878  0.739 40.248 
2.931   46.587   2  XX_U11A12:U87G88_XX X 11 ? X 88 ? X 12 ? X 87 ? 
1 A A 315 1_555 A U 390 1_555 A C 316 1_555 A G 389 1_555 -0.662 -1.583 2.963  -2.666  0.137    36.277  -2.553 0.721  2.996 0.219  
4.274   36.372   3  XX_A12C13:G86U87_XX X 12 ? X 87 ? X 13 ? X 86 ? 
1 A C 316 1_555 A G 389 1_555 A U 317 1_555 A A 388 1_555 0.238  -1.058 3.120  2.745   1.001    34.902  -1.901 -0.003 3.098 1.665  
-4.566  35.020   4  XX_C13U14:A85G86_XX X 13 ? X 86 ? X 14 ? X 85 ? 
1 A U 317 1_555 A A 388 1_555 A C 318 1_555 A G 354 1_555 0.737  -1.091 3.027  -3.871  5.397    39.264  -2.162 -1.483 2.777 7.962  
5.711   39.799   5  XX_U14C15:G51A85_XX X 14 ? X 85 ? X 15 ? X 51 ? 
1 A C 318 1_555 A G 354 1_555 A G 319 1_555 A C 353 1_555 0.477  -1.950 3.167  3.835   5.752    26.524  -5.423 -0.137 2.732 12.274 
-8.183  27.394   6  XX_C15G16:C50G51_XX X 15 ? X 51 ? X 16 ? X 50 ? 
1 A G 319 1_555 A C 353 1_555 A G 320 1_555 A C 352 1_555 -0.871 -1.542 3.464  -4.173  2.482    32.847  -3.140 0.785  3.423 4.360  
7.330   33.194   7  XX_G16G17:C49C50_XX X 16 ? X 50 ? X 17 ? X 49 ? 
1 A G 320 1_555 A C 352 1_555 A G 321 1_555 A C 351 1_555 -0.161 -1.321 3.129  1.374   8.025    33.430  -3.375 0.468  2.739 13.700 
-2.345  34.380   8  XX_G17G18:C48C49_XX X 17 ? X 49 ? X 18 ? X 48 ? 
1 A G 321 1_555 A C 351 1_555 A G 322 1_555 A A 350 1_555 -1.446 -0.947 3.113  2.923   2.586    34.138  -1.976 2.871  2.906 4.387  
-4.959  34.354   9  XX_G18G19:A47C48_XX X 18 ? X 48 ? X 19 ? X 47 ? 
1 A G 322 1_555 A A 350 1_555 A U 323 1_555 A A 348 1_555 0.629  0.485  3.365  -1.342  9.853    9.996   -8.052 -3.929 2.668 44.546 
6.070   14.090   10 XX_G19U20:A45A47_XX X 19 ? X 47 ? X 20 ? X 45 ? 
1 A U 335 1_555 A U 331 1_555 A G 336 1_555 A C 330 1_555 0.429  2.137  2.858  -23.195 -3.472   111.924 1.311  -0.482 2.730 -2.082 
13.908  113.532  11 XX_U32G33:C27U28_XX X 32 ? X 28 ? X 33 ? X 27 ? 
1 A G 336 1_555 A C 330 1_555 A A 337 1_555 A U 329 1_555 0.601  -1.168 3.483  1.614   0.944    29.912  -2.465 -0.809 3.473 1.827  
-3.122  29.969   12 XX_G33A34:U26C27_XX X 33 ? X 27 ? X 34 ? X 26 ? 
1 A A 337 1_555 A U 329 1_555 A A 338 1_555 A U 328 1_555 0.717  -2.254 3.127  -14.980 11.945   33.040  -4.679 -2.632 1.765 19.134 
23.997  38.059   13 XX_A34A35:U25U26_XX X 34 ? X 26 ? X 35 ? X 25 ? 
1 A A 338 1_555 A U 328 1_555 A G 339 1_555 A C 326 1_555 1.458  -1.961 3.387  9.213   8.007    51.154  -2.759 -1.025 3.266 9.125  
-10.499 52.495   14 XX_A35G36:C23U25_XX X 35 ? X 25 ? X 36 ? X 23 ? 
1 A G 339 1_555 A C 326 1_555 A G 340 1_555 A C 325 1_555 0.086  -1.868 2.929  -6.595  8.611    29.739  -4.731 -1.156 2.245 16.117 
12.345  31.614   15 XX_G36G37:C22C23_XX X 36 ? X 23 ? X 37 ? X 22 ? 
1 A G 340 1_555 A C 325 1_555 A C 341 1_555 A G 324 1_555 -0.574 -2.079 3.173  -0.324  8.669    37.813  -4.090 0.829  2.655 13.166 
0.493   38.760   16 XX_G37C38:G21C22_XX X 37 ? X 22 ? X 38 ? X 21 ? 
1 A C 341 1_555 A G 324 1_555 A U 342 1_555 A A 346 1_555 -3.492 -1.056 2.997  14.072  3.940    65.413  -1.084 3.618  2.231 3.599  
-12.855 66.848   17 XX_C38U39:A43G21_XX X 38 ? X 21 ? X 39 ? X 43 ? 
1 A A 356 1_555 A A 387 1_555 A A 359 1_555 A G 386 1_555 2.090  -2.508 0.806  95.751  132.585  129.942 -1.363 -0.970 0.392 66.912 
-48.322 173.058  18 XX_A53A56:G83A84_XX X 53 ? X 84 ? X 56 ? X 83 ? 
1 A A 359 1_555 A G 386 1_555 A C 360 1_555 A G 385 1_555 0.914  -0.959 3.500  -6.423  2.475    64.640  -1.002 -1.133 3.371 2.307  
5.989   64.966   19 XX_A56C57:G82G83_XX X 56 ? X 83 ? X 57 ? X 82 ? 
1 A C 360 1_555 A G 385 1_555 A C 361 1_555 A G 384 1_555 -1.402 -2.181 2.994  -1.191  9.401    26.473  -6.291 2.661  2.166 19.741 
2.502   28.090   20 XX_C57C58:G81G82_XX X 57 ? X 82 ? X 58 ? X 81 ? 
1 A C 361 1_555 A G 384 1_555 A U 362 1_555 A A 383 1_555 0.056  -1.638 3.233  0.129   3.670    37.817  -2.967 -0.070 3.067 5.646  
-0.199  37.988   21 XX_C58U59:A80G81_XX X 58 ? X 81 ? X 59 ? X 80 ? 
1 A U 362 1_555 A A 383 1_555 A G 363 1_555 A G 381 1_555 2.460  -1.942 2.996  16.935  8.048    92.813  -1.464 -1.385 3.174 5.512  
-11.599 94.262   22 XX_U59G60:G78A80_XX X 59 ? X 80 ? X 60 ? X 78 ? 
1 A G 363 1_555 A G 381 1_555 A A 364 1_555 A C 380 1_555 -2.925 -1.171 1.755  -32.271 168.921  77.335  -1.149 1.357  0.629 85.937 
16.417  173.737  23 XX_G60A61:C77G78_XX X 60 ? X 78 ? X 61 ? X 77 ? 
1 A A 364 1_555 A C 380 1_555 A C 366 1_555 A G 379 1_555 -3.202 -1.297 -1.039 103.888 -125.053 -15.852 0.607  -1.660 0.893 68.297 
56.738  -162.744 24 XX_A61C63:G76C77_XX X 61 ? X 77 ? X 63 ? X 76 ? 
1 A C 366 1_555 A G 379 1_555 A U 367 1_555 A A 378 1_555 -0.333 -1.584 3.289  -1.500  6.867    34.054  -3.660 0.337  2.935 11.573 
2.527   34.751   25 XX_C63U64:A75G76_XX X 63 ? X 76 ? X 64 ? X 75 ? 
1 A U 367 1_555 A A 378 1_555 A G 368 1_555 A C 377 1_555 0.016  -1.510 3.349  0.742   21.447   32.294  -4.659 0.058  2.001 34.249 
-1.186  38.616   26 XX_U64G65:C74A75_XX X 64 ? X 75 ? X 65 ? X 74 ? 
1 A G 368 1_555 A C 377 1_555 A G 369 1_555 A C 376 1_555 0.128  -1.902 2.842  -0.346  3.627    32.559  -3.896 -0.276 2.619 6.444  
0.615   32.757   27 XX_G65G66:C73C74_XX X 65 ? X 74 ? X 66 ? X 73 ? 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' R35GM141706 1 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' R35GM122532 2 
# 
_atom_sites.entry_id                    9C6K 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
MG 
N  
NA 
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    P  P     . G   A 1 313 ? 162.329 191.514 157.593 1.00 127.42 ? 10  G   X P     1 
ATOM   2    O  OP1   . G   A 1 313 ? 162.172 190.511 156.512 1.00 127.42 ? 10  G   X OP1   1 
ATOM   3    O  OP2   . G   A 1 313 ? 162.645 192.911 157.209 1.00 127.42 ? 10  G   X OP2   1 
ATOM   4    O  "O5'" . G   A 1 313 ? 161.013 191.546 158.498 1.00 127.42 ? 10  G   X "O5'" 1 
ATOM   5    C  "C5'" . G   A 1 313 ? 160.680 190.471 159.378 1.00 127.42 ? 10  G   X "C5'" 1 
ATOM   6    C  "C4'" . G   A 1 313 ? 159.391 190.744 160.113 1.00 127.42 ? 10  G   X "C4'" 1 
ATOM   7    O  "O4'" . G   A 1 313 ? 158.534 191.554 159.258 1.00 127.42 ? 10  G   X "O4'" 1 
ATOM   8    C  "C3'" . G   A 1 313 ? 158.564 189.510 160.484 1.00 127.42 ? 10  G   X "C3'" 1 
ATOM   9    O  "O3'" . G   A 1 313 ? 157.804 189.784 161.668 1.00 127.42 ? 10  G   X "O3'" 1 
ATOM   10   C  "C2'" . G   A 1 313 ? 157.610 189.414 159.306 1.00 127.42 ? 10  G   X "C2'" 1 
ATOM   11   O  "O2'" . G   A 1 313 ? 156.432 188.670 159.527 1.00 127.42 ? 10  G   X "O2'" 1 
ATOM   12   C  "C1'" . G   A 1 313 ? 157.307 190.883 159.062 1.00 127.42 ? 10  G   X "C1'" 1 
ATOM   13   N  N9    . G   A 1 313 ? 156.808 191.140 157.717 1.00 127.42 ? 10  G   X N9    1 
ATOM   14   C  C8    . G   A 1 313 ? 157.443 190.822 156.549 1.00 127.42 ? 10  G   X C8    1 
ATOM   15   N  N7    . G   A 1 313 ? 156.749 191.132 155.494 1.00 127.42 ? 10  G   X N7    1 
ATOM   16   C  C5    . G   A 1 313 ? 155.582 191.671 156.006 1.00 127.42 ? 10  G   X C5    1 
ATOM   17   C  C6    . G   A 1 313 ? 154.458 192.184 155.328 1.00 127.42 ? 10  G   X C6    1 
ATOM   18   O  O6    . G   A 1 313 ? 154.270 192.261 154.111 1.00 127.42 ? 10  G   X O6    1 
ATOM   19   N  N1    . G   A 1 313 ? 153.492 192.636 156.215 1.00 127.42 ? 10  G   X N1    1 
ATOM   20   C  C2    . G   A 1 313 ? 153.591 192.597 157.583 1.00 127.42 ? 10  G   X C2    1 
ATOM   21   N  N2    . G   A 1 313 ? 152.539 193.086 158.255 1.00 127.42 ? 10  G   X N2    1 
ATOM   22   N  N3    . G   A 1 313 ? 154.643 192.120 158.232 1.00 127.42 ? 10  G   X N3    1 
ATOM   23   C  C4    . G   A 1 313 ? 155.593 191.679 157.381 1.00 127.42 ? 10  G   X C4    1 
ATOM   24   P  P     . U   A 1 314 ? 156.905 188.641 162.368 1.00 123.35 ? 11  U   X P     1 
ATOM   25   O  OP1   . U   A 1 314 ? 156.795 188.950 163.811 1.00 123.35 ? 11  U   X OP1   1 
ATOM   26   O  OP2   . U   A 1 314 ? 157.416 187.324 161.926 1.00 123.35 ? 11  U   X OP2   1 
ATOM   27   O  "O5'" . U   A 1 314 ? 155.446 188.826 161.750 1.00 123.35 ? 11  U   X "O5'" 1 
ATOM   28   C  "C5'" . U   A 1 314 ? 154.465 187.799 161.871 1.00 123.35 ? 11  U   X "C5'" 1 
ATOM   29   C  "C4'" . U   A 1 314 ? 153.085 188.286 161.483 1.00 123.35 ? 11  U   X "C4'" 1 
ATOM   30   O  "O4'" . U   A 1 314 ? 153.192 189.253 160.410 1.00 123.35 ? 11  U   X "O4'" 1 
ATOM   31   C  "C3'" . U   A 1 314 ? 152.114 187.237 160.948 1.00 123.35 ? 11  U   X "C3'" 1 
ATOM   32   O  "O3'" . U   A 1 314 ? 151.452 186.517 161.974 1.00 123.35 ? 11  U   X "O3'" 1 
ATOM   33   C  "C2'" . U   A 1 314 ? 151.157 188.058 160.099 1.00 123.35 ? 11  U   X "C2'" 1 
ATOM   34   O  "O2'" . U   A 1 314 ? 150.164 188.665 160.909 1.00 123.35 ? 11  U   X "O2'" 1 
ATOM   35   C  "C1'" . U   A 1 314 ? 152.077 189.150 159.552 1.00 123.35 ? 11  U   X "C1'" 1 
ATOM   36   N  N1    . U   A 1 314 ? 152.557 188.831 158.197 1.00 123.35 ? 11  U   X N1    1 
ATOM   37   C  C2    . U   A 1 314 ? 151.720 189.135 157.154 1.00 123.35 ? 11  U   X C2    1 
ATOM   38   O  O2    . U   A 1 314 ? 150.630 189.648 157.318 1.00 123.35 ? 11  U   X O2    1 
ATOM   39   N  N3    . U   A 1 314 ? 152.206 188.821 155.917 1.00 123.35 ? 11  U   X N3    1 
ATOM   40   C  C4    . U   A 1 314 ? 153.425 188.242 155.643 1.00 123.35 ? 11  U   X C4    1 
ATOM   41   O  O4    . U   A 1 314 ? 153.735 188.011 154.476 1.00 123.35 ? 11  U   X O4    1 
ATOM   42   C  C5    . U   A 1 314 ? 154.235 187.959 156.782 1.00 123.35 ? 11  U   X C5    1 
ATOM   43   C  C6    . U   A 1 314 ? 153.780 188.255 157.996 1.00 123.35 ? 11  U   X C6    1 
ATOM   44   P  P     . A   A 1 315 ? 150.655 185.162 161.636 1.00 114.05 ? 12  A   X P     1 
ATOM   45   O  OP1   . A   A 1 315 ? 150.567 184.375 162.885 1.00 114.05 ? 12  A   X OP1   1 
ATOM   46   O  OP2   . A   A 1 315 ? 151.255 184.548 160.429 1.00 114.05 ? 12  A   X OP2   1 
ATOM   47   O  "O5'" . A   A 1 315 ? 149.179 185.627 161.255 1.00 114.05 ? 12  A   X "O5'" 1 
ATOM   48   C  "C5'" . A   A 1 315 ? 148.198 184.658 160.903 1.00 114.05 ? 12  A   X "C5'" 1 
ATOM   49   C  "C4'" . A   A 1 315 ? 147.049 185.246 160.115 1.00 114.05 ? 12  A   X "C4'" 1 
ATOM   50   O  "O4'" . A   A 1 315 ? 147.482 186.440 159.420 1.00 114.05 ? 12  A   X "O4'" 1 
ATOM   51   C  "C3'" . A   A 1 315 ? 146.476 184.349 159.025 1.00 114.05 ? 12  A   X "C3'" 1 
ATOM   52   O  "O3'" . A   A 1 315 ? 145.501 183.453 159.529 1.00 114.05 ? 12  A   X "O3'" 1 
ATOM   53   C  "C2'" . A   A 1 315 ? 145.911 185.340 158.012 1.00 114.05 ? 12  A   X "C2'" 1 
ATOM   54   O  "O2'" . A   A 1 315 ? 144.614 185.768 158.396 1.00 114.05 ? 12  A   X "O2'" 1 
ATOM   55   C  "C1'" . A   A 1 315 ? 146.870 186.519 158.152 1.00 114.05 ? 12  A   X "C1'" 1 
ATOM   56   N  N9    . A   A 1 315 ? 147.940 186.530 157.138 1.00 114.05 ? 12  A   X N9    1 
ATOM   57   C  C8    . A   A 1 315 ? 149.268 186.529 157.450 1.00 114.05 ? 12  A   X C8    1 
ATOM   58   N  N7    . A   A 1 315 ? 150.059 186.572 156.421 1.00 114.05 ? 12  A   X N7    1 
ATOM   59   C  C5    . A   A 1 315 ? 149.184 186.617 155.367 1.00 114.05 ? 12  A   X C5    1 
ATOM   60   C  C6    . A   A 1 315 ? 149.437 186.672 154.021 1.00 114.05 ? 12  A   X C6    1 
ATOM   61   N  N6    . A   A 1 315 ? 150.676 186.695 153.556 1.00 114.05 ? 12  A   X N6    1 
ATOM   62   N  N1    . A   A 1 315 ? 148.407 186.721 153.180 1.00 114.05 ? 12  A   X N1    1 
ATOM   63   C  C2    . A   A 1 315 ? 147.180 186.705 153.692 1.00 114.05 ? 12  A   X C2    1 
ATOM   64   N  N3    . A   A 1 315 ? 146.810 186.643 154.966 1.00 114.05 ? 12  A   X N3    1 
ATOM   65   C  C4    . A   A 1 315 ? 147.878 186.607 155.768 1.00 114.05 ? 12  A   X C4    1 
ATOM   66   P  P     . C   A 1 316 ? 145.211 182.060 158.790 1.00 104.95 ? 13  C   X P     1 
ATOM   67   O  OP1   . C   A 1 316 ? 144.138 181.372 159.540 1.00 104.95 ? 13  C   X OP1   1 
ATOM   68   O  OP2   . C   A 1 316 ? 146.513 181.388 158.586 1.00 104.95 ? 13  C   X OP2   1 
ATOM   69   O  "O5'" . C   A 1 316 ? 144.607 182.475 157.376 1.00 104.95 ? 13  C   X "O5'" 1 
ATOM   70   C  "C5'" . C   A 1 316 ? 143.226 182.306 157.094 1.00 104.95 ? 13  C   X "C5'" 1 
ATOM   71   C  "C4'" . C   A 1 316 ? 142.906 182.661 155.664 1.00 104.95 ? 13  C   X "C4'" 1 
ATOM   72   O  "O4'" . C   A 1 316 ? 143.740 183.766 155.255 1.00 104.95 ? 13  C   X "O4'" 1 
ATOM   73   C  "C3'" . C   A 1 316 ? 143.166 181.578 154.627 1.00 104.95 ? 13  C   X "C3'" 1 
ATOM   74   O  "O3'" . C   A 1 316 ? 142.050 180.715 154.494 1.00 104.95 ? 13  C   X "O3'" 1 
ATOM   75   C  "C2'" . C   A 1 316 ? 143.455 182.368 153.360 1.00 104.95 ? 13  C   X "C2'" 1 
ATOM   76   O  "O2'" . C   A 1 316 ? 142.252 182.730 152.709 1.00 104.95 ? 13  C   X "O2'" 1 
ATOM   77   C  "C1'" . C   A 1 316 ? 144.109 183.630 153.907 1.00 104.95 ? 13  C   X "C1'" 1 
ATOM   78   N  N1    . C   A 1 316 ? 145.582 183.612 153.850 1.00 104.95 ? 13  C   X N1    1 
ATOM   79   C  C2    . C   A 1 316 ? 146.241 183.684 152.638 1.00 104.95 ? 13  C   X C2    1 
ATOM   80   O  O2    . C   A 1 316 ? 145.576 183.713 151.597 1.00 104.95 ? 13  C   X O2    1 
ATOM   81   N  N3    . C   A 1 316 ? 147.586 183.691 152.636 1.00 104.95 ? 13  C   X N3    1 
ATOM   82   C  C4    . C   A 1 316 ? 148.258 183.653 153.784 1.00 104.95 ? 13  C   X C4    1 
ATOM   83   N  N4    . C   A 1 316 ? 149.583 183.667 153.732 1.00 104.95 ? 13  C   X N4    1 
ATOM   84   C  C5    . C   A 1 316 ? 147.614 183.605 155.036 1.00 104.95 ? 13  C   X C5    1 
ATOM   85   C  C6    . C   A 1 316 ? 146.284 183.595 155.014 1.00 104.95 ? 13  C   X C6    1 
ATOM   86   P  P     . U   A 1 317 ? 142.201 179.232 153.907 1.00 97.14  ? 14  U   X P     1 
ATOM   87   O  OP1   . U   A 1 317 ? 140.843 178.678 153.735 1.00 97.14  ? 14  U   X OP1   1 
ATOM   88   O  OP2   . U   A 1 317 ? 143.209 178.489 154.697 1.00 97.14  ? 14  U   X OP2   1 
ATOM   89   O  "O5'" . U   A 1 317 ? 142.740 179.461 152.437 1.00 97.14  ? 14  U   X "O5'" 1 
ATOM   90   C  "C5'" . U   A 1 317 ? 141.862 179.855 151.399 1.00 97.14  ? 14  U   X "C5'" 1 
ATOM   91   C  "C4'" . U   A 1 317 ? 142.588 179.866 150.082 1.00 97.14  ? 14  U   X "C4'" 1 
ATOM   92   O  "O4'" . U   A 1 317 ? 143.569 180.932 150.093 1.00 97.14  ? 14  U   X "O4'" 1 
ATOM   93   C  "C3'" . U   A 1 317 ? 143.404 178.619 149.781 1.00 97.14  ? 14  U   X "C3'" 1 
ATOM   94   O  "O3'" . U   A 1 317 ? 142.635 177.575 149.220 1.00 97.14  ? 14  U   X "O3'" 1 
ATOM   95   C  "C2'" . U   A 1 317 ? 144.474 179.142 148.848 1.00 97.14  ? 14  U   X "C2'" 1 
ATOM   96   O  "O2'" . U   A 1 317 ? 143.940 179.313 147.548 1.00 97.14  ? 14  U   X "O2'" 1 
ATOM   97   C  "C1'" . U   A 1 317 ? 144.743 180.515 149.439 1.00 97.14  ? 14  U   X "C1'" 1 
ATOM   98   N  N1    . U   A 1 317 ? 145.841 180.524 150.427 1.00 97.14  ? 14  U   X N1    1 
ATOM   99   C  C2    . U   A 1 317 ? 147.115 180.635 149.968 1.00 97.14  ? 14  U   X C2    1 
ATOM   100  O  O2    . U   A 1 317 ? 147.371 180.678 148.789 1.00 97.14  ? 14  U   X O2    1 
ATOM   101  N  N3    . U   A 1 317 ? 148.090 180.675 150.917 1.00 97.14  ? 14  U   X N3    1 
ATOM   102  C  C4    . U   A 1 317 ? 147.927 180.637 152.279 1.00 97.14  ? 14  U   X C4    1 
ATOM   103  O  O4    . U   A 1 317 ? 148.910 180.684 153.015 1.00 97.14  ? 14  U   X O4    1 
ATOM   104  C  C5    . U   A 1 317 ? 146.574 180.536 152.687 1.00 97.14  ? 14  U   X C5    1 
ATOM   105  C  C6    . U   A 1 317 ? 145.613 180.488 151.766 1.00 97.14  ? 14  U   X C6    1 
ATOM   106  P  P     . C   A 1 318 ? 143.065 176.049 149.447 1.00 92.86  ? 15  C   X P     1 
ATOM   107  O  OP1   . C   A 1 318 ? 142.041 175.202 148.798 1.00 92.86  ? 15  C   X OP1   1 
ATOM   108  O  OP2   . C   A 1 318 ? 143.405 175.838 150.870 1.00 92.86  ? 15  C   X OP2   1 
ATOM   109  O  "O5'" . C   A 1 318 ? 144.406 175.916 148.612 1.00 92.86  ? 15  C   X "O5'" 1 
ATOM   110  C  "C5'" . C   A 1 318 ? 144.393 176.098 147.209 1.00 92.86  ? 15  C   X "C5'" 1 
ATOM   111  C  "C4'" . C   A 1 318 ? 145.784 176.276 146.669 1.00 92.86  ? 15  C   X "C4'" 1 
ATOM   112  O  "O4'" . C   A 1 318 ? 146.381 177.473 147.227 1.00 92.86  ? 15  C   X "O4'" 1 
ATOM   113  C  "C3'" . C   A 1 318 ? 146.773 175.186 147.021 1.00 92.86  ? 15  C   X "C3'" 1 
ATOM   114  O  "O3'" . C   A 1 318 ? 146.645 174.037 146.207 1.00 92.86  ? 15  C   X "O3'" 1 
ATOM   115  C  "C2'" . C   A 1 318 ? 148.100 175.900 146.858 1.00 92.86  ? 15  C   X "C2'" 1 
ATOM   116  O  "O2'" . C   A 1 318 ? 148.414 176.040 145.483 1.00 92.86  ? 15  C   X "O2'" 1 
ATOM   117  C  "C1'" . C   A 1 318 ? 147.764 177.279 147.402 1.00 92.86  ? 15  C   X "C1'" 1 
ATOM   118  N  N1    . C   A 1 318 ? 148.085 177.409 148.838 1.00 92.86  ? 15  C   X N1    1 
ATOM   119  C  C2    . C   A 1 318 ? 149.413 177.538 149.223 1.00 92.86  ? 15  C   X C2    1 
ATOM   120  O  O2    . C   A 1 318 ? 150.289 177.511 148.353 1.00 92.86  ? 15  C   X O2    1 
ATOM   121  N  N3    . C   A 1 318 ? 149.714 177.659 150.530 1.00 92.86  ? 15  C   X N3    1 
ATOM   122  C  C4    . C   A 1 318 ? 148.747 177.671 151.436 1.00 92.86  ? 15  C   X C4    1 
ATOM   123  N  N4    . C   A 1 318 ? 149.093 177.800 152.714 1.00 92.86  ? 15  C   X N4    1 
ATOM   124  C  C5    . C   A 1 318 ? 147.383 177.557 151.078 1.00 92.86  ? 15  C   X C5    1 
ATOM   125  C  C6    . C   A 1 318 ? 147.108 177.425 149.781 1.00 92.86  ? 15  C   X C6    1 
ATOM   126  P  P     . G   A 1 319 ? 147.024 172.592 146.791 1.00 86.15  ? 16  G   X P     1 
ATOM   127  O  OP1   . G   A 1 319 ? 146.772 171.592 145.733 1.00 86.15  ? 16  G   X OP1   1 
ATOM   128  O  OP2   . G   A 1 319 ? 146.381 172.432 148.112 1.00 86.15  ? 16  G   X OP2   1 
ATOM   129  O  "O5'" . G   A 1 319 ? 148.597 172.661 146.997 1.00 86.15  ? 16  G   X "O5'" 1 
ATOM   130  C  "C5'" . G   A 1 319 ? 149.450 172.814 145.880 1.00 86.15  ? 16  G   X "C5'" 1 
ATOM   131  C  "C4'" . G   A 1 319 ? 150.819 173.301 146.276 1.00 86.15  ? 16  G   X "C4'" 1 
ATOM   132  O  "O4'" . G   A 1 319 ? 150.719 174.480 147.100 1.00 86.15  ? 16  G   X "O4'" 1 
ATOM   133  C  "C3'" . G   A 1 319 ? 151.658 172.357 147.110 1.00 86.15  ? 16  G   X "C3'" 1 
ATOM   134  O  "O3'" . G   A 1 319 ? 152.262 171.355 146.327 1.00 86.15  ? 16  G   X "O3'" 1 
ATOM   135  C  "C2'" . G   A 1 319 ? 152.670 173.296 147.735 1.00 86.15  ? 16  G   X "C2'" 1 
ATOM   136  O  "O2'" . G   A 1 319 ? 153.675 173.620 146.791 1.00 86.15  ? 16  G   X "O2'" 1 
ATOM   137  C  "C1'" . G   A 1 319 ? 151.828 174.547 147.962 1.00 86.15  ? 16  G   X "C1'" 1 
ATOM   138  N  N9    . G   A 1 319 ? 151.367 174.693 149.351 1.00 86.15  ? 16  G   X N9    1 
ATOM   139  C  C8    . G   A 1 319 ? 150.088 174.660 149.824 1.00 86.15  ? 16  G   X C8    1 
ATOM   140  N  N7    . G   A 1 319 ? 150.017 174.848 151.108 1.00 86.15  ? 16  G   X N7    1 
ATOM   141  C  C5    . G   A 1 319 ? 151.329 175.014 151.497 1.00 86.15  ? 16  G   X C5    1 
ATOM   142  C  C6    . G   A 1 319 ? 151.889 175.246 152.770 1.00 86.15  ? 16  G   X C6    1 
ATOM   143  O  O6    . G   A 1 319 ? 151.320 175.365 153.859 1.00 86.15  ? 16  G   X O6    1 
ATOM   144  N  N1    . G   A 1 319 ? 153.268 175.352 152.713 1.00 86.15  ? 16  G   X N1    1 
ATOM   145  C  C2    . G   A 1 319 ? 154.009 175.246 151.574 1.00 86.15  ? 16  G   X C2    1 
ATOM   146  N  N2    . G   A 1 319 ? 155.329 175.374 151.698 1.00 86.15  ? 16  G   X N2    1 
ATOM   147  N  N3    . G   A 1 319 ? 153.500 175.031 150.387 1.00 86.15  ? 16  G   X N3    1 
ATOM   148  C  C4    . G   A 1 319 ? 152.168 174.926 150.425 1.00 86.15  ? 16  G   X C4    1 
ATOM   149  P  P     . G   A 1 320 ? 152.469 169.890 146.923 1.00 84.37  ? 17  G   X P     1 
ATOM   150  O  OP1   . G   A 1 320 ? 152.374 168.931 145.804 1.00 84.37  ? 17  G   X OP1   1 
ATOM   151  O  OP2   . G   A 1 320 ? 151.609 169.750 148.117 1.00 84.37  ? 17  G   X OP2   1 
ATOM   152  O  "O5'" . G   A 1 320 ? 153.968 169.910 147.432 1.00 84.37  ? 17  G   X "O5'" 1 
ATOM   153  C  "C5'" . G   A 1 320 ? 154.949 170.669 146.751 1.00 84.37  ? 17  G   X "C5'" 1 
ATOM   154  C  "C4'" . G   A 1 320 ? 156.066 171.047 147.682 1.00 84.37  ? 17  G   X "C4'" 1 
ATOM   155  O  "O4'" . G   A 1 320 ? 155.655 172.143 148.526 1.00 84.37  ? 17  G   X "O4'" 1 
ATOM   156  C  "C3'" . G   A 1 320 ? 156.475 169.974 148.663 1.00 84.37  ? 17  G   X "C3'" 1 
ATOM   157  O  "O3'" . G   A 1 320 ? 157.333 169.017 148.088 1.00 84.37  ? 17  G   X "O3'" 1 
ATOM   158  C  "C2'" . G   A 1 320 ? 157.118 170.773 149.782 1.00 84.37  ? 17  G   X "C2'" 1 
ATOM   159  O  "O2'" . G   A 1 320 ? 158.433 171.154 149.419 1.00 84.37  ? 17  G   X "O2'" 1 
ATOM   160  C  "C1'" . G   A 1 320 ? 156.261 172.025 149.790 1.00 84.37  ? 17  G   X "C1'" 1 
ATOM   161  N  N9    . G   A 1 320 ? 155.213 172.031 150.824 1.00 84.37  ? 17  G   X N9    1 
ATOM   162  C  C8    . G   A 1 320 ? 153.872 172.013 150.591 1.00 84.37  ? 17  G   X C8    1 
ATOM   163  N  N7    . G   A 1 320 ? 153.155 172.079 151.666 1.00 84.37  ? 17  G   X N7    1 
ATOM   164  C  C5    . G   A 1 320 ? 154.088 172.150 152.673 1.00 84.37  ? 17  G   X C5    1 
ATOM   165  C  C6    . G   A 1 320 ? 153.894 172.235 154.058 1.00 84.37  ? 17  G   X C6    1 
ATOM   166  O  O6    . G   A 1 320 ? 152.826 172.263 154.670 1.00 84.37  ? 17  G   X O6    1 
ATOM   167  N  N1    . G   A 1 320 ? 155.090 172.293 154.748 1.00 84.37  ? 17  G   X N1    1 
ATOM   168  C  C2    . G   A 1 320 ? 156.319 172.268 154.168 1.00 84.37  ? 17  G   X C2    1 
ATOM   169  N  N2    . G   A 1 320 ? 157.366 172.338 154.995 1.00 84.37  ? 17  G   X N2    1 
ATOM   170  N  N3    . G   A 1 320 ? 156.514 172.188 152.866 1.00 84.37  ? 17  G   X N3    1 
ATOM   171  C  C4    . G   A 1 320 ? 155.361 172.134 152.181 1.00 84.37  ? 17  G   X C4    1 
ATOM   172  P  P     . G   A 1 321 ? 157.335 167.533 148.667 1.00 84.56  ? 18  G   X P     1 
ATOM   173  O  OP1   . G   A 1 321 ? 158.341 166.736 147.940 1.00 84.56  ? 18  G   X OP1   1 
ATOM   174  O  OP2   . G   A 1 321 ? 155.932 167.079 148.775 1.00 84.56  ? 18  G   X OP2   1 
ATOM   175  O  "O5'" . G   A 1 321 ? 157.901 167.727 150.128 1.00 84.56  ? 18  G   X "O5'" 1 
ATOM   176  C  "C5'" . G   A 1 321 ? 159.213 168.211 150.331 1.00 84.56  ? 18  G   X "C5'" 1 
ATOM   177  C  "C4'" . G   A 1 321 ? 159.614 167.996 151.754 1.00 84.56  ? 18  G   X "C4'" 1 
ATOM   178  O  "O4'" . G   A 1 321 ? 159.033 169.019 152.591 1.00 84.56  ? 18  G   X "O4'" 1 
ATOM   179  C  "C3'" . G   A 1 321 ? 159.099 166.707 152.345 1.00 84.56  ? 18  G   X "C3'" 1 
ATOM   180  O  "O3'" . G   A 1 321 ? 159.898 165.609 151.952 1.00 84.56  ? 18  G   X "O3'" 1 
ATOM   181  C  "C2'" . G   A 1 321 ? 159.092 167.009 153.832 1.00 84.56  ? 18  G   X "C2'" 1 
ATOM   182  O  "O2'" . G   A 1 321 ? 160.401 166.900 154.363 1.00 84.56  ? 18  G   X "O2'" 1 
ATOM   183  C  "C1'" . G   A 1 321 ? 158.693 168.477 153.844 1.00 84.56  ? 18  G   X "C1'" 1 
ATOM   184  N  N9    . G   A 1 321 ? 157.252 168.680 154.050 1.00 84.56  ? 18  G   X N9    1 
ATOM   185  C  C8    . G   A 1 321 ? 156.291 168.673 153.084 1.00 84.56  ? 18  G   X C8    1 
ATOM   186  N  N7    . G   A 1 321 ? 155.099 168.900 153.540 1.00 84.56  ? 18  G   X N7    1 
ATOM   187  C  C5    . G   A 1 321 ? 155.288 169.074 154.892 1.00 84.56  ? 18  G   X C5    1 
ATOM   188  C  C6    . G   A 1 321 ? 154.352 169.348 155.907 1.00 84.56  ? 18  G   X C6    1 
ATOM   189  O  O6    . G   A 1 321 ? 153.136 169.499 155.797 1.00 84.56  ? 18  G   X O6    1 
ATOM   190  N  N1    . G   A 1 321 ? 154.950 169.452 157.148 1.00 84.56  ? 18  G   X N1    1 
ATOM   191  C  C2    . G   A 1 321 ? 156.286 169.311 157.377 1.00 84.56  ? 18  G   X C2    1 
ATOM   192  N  N2    . G   A 1 321 ? 156.688 169.445 158.641 1.00 84.56  ? 18  G   X N2    1 
ATOM   193  N  N3    . G   A 1 321 ? 157.173 169.050 156.438 1.00 84.56  ? 18  G   X N3    1 
ATOM   194  C  C4    . G   A 1 321 ? 156.607 168.945 155.225 1.00 84.56  ? 18  G   X C4    1 
ATOM   195  P  P     . G   A 1 322 ? 160.021 164.302 152.857 1.00 87.83  ? 19  G   X P     1 
ATOM   196  O  OP1   . G   A 1 322 ? 160.771 163.297 152.077 1.00 87.83  ? 19  G   X OP1   1 
ATOM   197  O  OP2   . G   A 1 322 ? 158.672 163.964 153.358 1.00 87.83  ? 19  G   X OP2   1 
ATOM   198  O  "O5'" . G   A 1 322 ? 160.962 164.775 154.046 1.00 87.83  ? 19  G   X "O5'" 1 
ATOM   199  C  "C5'" . G   A 1 322 ? 161.694 163.845 154.813 1.00 87.83  ? 19  G   X "C5'" 1 
ATOM   200  C  "C4'" . G   A 1 322 ? 161.424 164.027 156.277 1.00 87.83  ? 19  G   X "C4'" 1 
ATOM   201  O  "O4'" . G   A 1 322 ? 160.586 165.180 156.494 1.00 87.83  ? 19  G   X "O4'" 1 
ATOM   202  C  "C3'" . G   A 1 322 ? 160.673 162.897 156.934 1.00 87.83  ? 19  G   X "C3'" 1 
ATOM   203  O  "O3'" . G   A 1 322 ? 161.550 161.855 157.282 1.00 87.83  ? 19  G   X "O3'" 1 
ATOM   204  C  "C2'" . G   A 1 322 ? 160.046 163.566 158.145 1.00 87.83  ? 19  G   X "C2'" 1 
ATOM   205  O  "O2'" . G   A 1 322 ? 160.997 163.652 159.188 1.00 87.83  ? 19  G   X "O2'" 1 
ATOM   206  C  "C1'" . G   A 1 322 ? 159.785 164.976 157.632 1.00 87.83  ? 19  G   X "C1'" 1 
ATOM   207  N  N9    . G   A 1 322 ? 158.382 165.238 157.282 1.00 87.83  ? 19  G   X N9    1 
ATOM   208  C  C8    . G   A 1 322 ? 157.817 165.165 156.050 1.00 87.83  ? 19  G   X C8    1 
ATOM   209  N  N7    . G   A 1 322 ? 156.566 165.500 156.023 1.00 87.83  ? 19  G   X N7    1 
ATOM   210  C  C5    . G   A 1 322 ? 156.291 165.809 157.334 1.00 87.83  ? 19  G   X C5    1 
ATOM   211  C  C6    . G   A 1 322 ? 155.090 166.236 157.923 1.00 87.83  ? 19  G   X C6    1 
ATOM   212  O  O6    . G   A 1 322 ? 154.008 166.427 157.372 1.00 87.83  ? 19  G   X O6    1 
ATOM   213  N  N1    . G   A 1 322 ? 155.235 166.446 159.280 1.00 87.83  ? 19  G   X N1    1 
ATOM   214  C  C2    . G   A 1 322 ? 156.393 166.267 159.972 1.00 87.83  ? 19  G   X C2    1 
ATOM   215  N  N2    . G   A 1 322 ? 156.330 166.521 161.278 1.00 87.83  ? 19  G   X N2    1 
ATOM   216  N  N3    . G   A 1 322 ? 157.521 165.872 159.435 1.00 87.83  ? 19  G   X N3    1 
ATOM   217  C  C4    . G   A 1 322 ? 157.395 165.665 158.120 1.00 87.83  ? 19  G   X C4    1 
ATOM   218  P  P     . U   A 1 323 ? 161.459 160.452 156.537 1.00 89.37  ? 20  U   X P     1 
ATOM   219  O  OP1   . U   A 1 323 ? 162.819 159.878 156.522 1.00 89.37  ? 20  U   X OP1   1 
ATOM   220  O  OP2   . U   A 1 323 ? 160.702 160.632 155.279 1.00 89.37  ? 20  U   X OP2   1 
ATOM   221  O  "O5'" . U   A 1 323 ? 160.605 159.588 157.552 1.00 89.37  ? 20  U   X "O5'" 1 
ATOM   222  C  "C5'" . U   A 1 323 ? 161.071 159.427 158.876 1.00 89.37  ? 20  U   X "C5'" 1 
ATOM   223  C  "C4'" . U   A 1 323 ? 159.997 159.682 159.897 1.00 89.37  ? 20  U   X "C4'" 1 
ATOM   224  O  "O4'" . U   A 1 323 ? 159.388 160.970 159.677 1.00 89.37  ? 20  U   X "O4'" 1 
ATOM   225  C  "C3'" . U   A 1 323 ? 158.819 158.731 159.910 1.00 89.37  ? 20  U   X "C3'" 1 
ATOM   226  O  "O3'" . U   A 1 323 ? 159.113 157.508 160.549 1.00 89.37  ? 20  U   X "O3'" 1 
ATOM   227  C  "C2'" . U   A 1 323 ? 157.766 159.537 160.647 1.00 89.37  ? 20  U   X "C2'" 1 
ATOM   228  O  "O2'" . U   A 1 323 ? 157.991 159.475 162.042 1.00 89.37  ? 20  U   X "O2'" 1 
ATOM   229  C  "C1'" . U   A 1 323 ? 158.073 160.957 160.178 1.00 89.37  ? 20  U   X "C1'" 1 
ATOM   230  N  N1    . U   A 1 323 ? 157.127 161.389 159.137 1.00 89.37  ? 20  U   X N1    1 
ATOM   231  C  C2    . U   A 1 323 ? 155.938 161.844 159.622 1.00 89.37  ? 20  U   X C2    1 
ATOM   232  O  O2    . U   A 1 323 ? 155.702 161.912 160.807 1.00 89.37  ? 20  U   X O2    1 
ATOM   233  N  N3    . U   A 1 323 ? 155.027 162.239 158.699 1.00 89.37  ? 20  U   X N3    1 
ATOM   234  C  C4    . U   A 1 323 ? 155.199 162.207 157.341 1.00 89.37  ? 20  U   X C4    1 
ATOM   235  O  O4    . U   A 1 323 ? 154.286 162.594 156.620 1.00 89.37  ? 20  U   X O4    1 
ATOM   236  C  C5    . U   A 1 323 ? 156.461 161.711 156.908 1.00 89.37  ? 20  U   X C5    1 
ATOM   237  C  C6    . U   A 1 323 ? 157.365 161.316 157.799 1.00 89.37  ? 20  U   X C6    1 
ATOM   238  P  P     . G   A 1 324 ? 159.761 156.314 159.708 1.00 89.81  ? 21  G   X P     1 
ATOM   239  O  OP1   . G   A 1 324 ? 159.379 156.523 158.296 1.00 89.81  ? 21  G   X OP1   1 
ATOM   240  O  OP2   . G   A 1 324 ? 159.455 155.037 160.383 1.00 89.81  ? 21  G   X OP2   1 
ATOM   241  O  "O5'" . G   A 1 324 ? 161.324 156.560 159.844 1.00 89.81  ? 21  G   X "O5'" 1 
ATOM   242  C  "C5'" . G   A 1 324 ? 162.074 155.858 160.815 1.00 89.81  ? 21  G   X "C5'" 1 
ATOM   243  C  "C4'" . G   A 1 324 ? 163.284 156.625 161.272 1.00 89.81  ? 21  G   X "C4'" 1 
ATOM   244  O  "O4'" . G   A 1 324 ? 162.880 157.912 161.799 1.00 89.81  ? 21  G   X "O4'" 1 
ATOM   245  C  "C3'" . G   A 1 324 ? 164.034 155.968 162.408 1.00 89.81  ? 21  G   X "C3'" 1 
ATOM   246  O  "O3'" . G   A 1 324 ? 164.955 155.008 161.942 1.00 89.81  ? 21  G   X "O3'" 1 
ATOM   247  C  "C2'" . G   A 1 324 ? 164.667 157.142 163.134 1.00 89.81  ? 21  G   X "C2'" 1 
ATOM   248  O  "O2'" . G   A 1 324 ? 165.824 157.586 162.452 1.00 89.81  ? 21  G   X "O2'" 1 
ATOM   249  C  "C1'" . G   A 1 324 ? 163.591 158.203 162.975 1.00 89.81  ? 21  G   X "C1'" 1 
ATOM   250  N  N9    . G   A 1 324 ? 162.617 158.174 164.070 1.00 89.81  ? 21  G   X N9    1 
ATOM   251  C  C8    . G   A 1 324 ? 161.278 158.070 163.861 1.00 89.81  ? 21  G   X C8    1 
ATOM   252  N  N7    . G   A 1 324 ? 160.588 158.057 164.948 1.00 89.81  ? 21  G   X N7    1 
ATOM   253  C  C5    . G   A 1 324 ? 161.537 158.171 165.926 1.00 89.81  ? 21  G   X C5    1 
ATOM   254  C  C6    . G   A 1 324 ? 161.345 158.202 167.301 1.00 89.81  ? 21  G   X C6    1 
ATOM   255  O  O6    . G   A 1 324 ? 160.274 158.144 167.900 1.00 89.81  ? 21  G   X O6    1 
ATOM   256  N  N1    . G   A 1 324 ? 162.543 158.313 167.969 1.00 89.81  ? 21  G   X N1    1 
ATOM   257  C  C2    . G   A 1 324 ? 163.774 158.388 167.381 1.00 89.81  ? 21  G   X C2    1 
ATOM   258  N  N2    . G   A 1 324 ? 164.811 158.495 168.213 1.00 89.81  ? 21  G   X N2    1 
ATOM   259  N  N3    . G   A 1 324 ? 163.965 158.353 166.080 1.00 89.81  ? 21  G   X N3    1 
ATOM   260  C  C4    . G   A 1 324 ? 162.803 158.245 165.420 1.00 89.81  ? 21  G   X C4    1 
ATOM   261  P  P     . C   A 1 325 ? 164.666 153.455 162.185 1.00 93.44  ? 22  C   X P     1 
ATOM   262  O  OP1   . C   A 1 325 ? 165.326 152.665 161.125 1.00 93.44  ? 22  C   X OP1   1 
ATOM   263  O  OP2   . C   A 1 325 ? 163.215 153.295 162.411 1.00 93.44  ? 22  C   X OP2   1 
ATOM   264  O  "O5'" . C   A 1 325 ? 165.426 153.167 163.546 1.00 93.44  ? 22  C   X "O5'" 1 
ATOM   265  C  "C5'" . C   A 1 325 ? 166.718 153.706 163.751 1.00 93.44  ? 22  C   X "C5'" 1 
ATOM   266  C  "C4'" . C   A 1 325 ? 166.977 153.987 165.202 1.00 93.44  ? 22  C   X "C4'" 1 
ATOM   267  O  "O4'" . C   A 1 325 ? 166.178 155.105 165.650 1.00 93.44  ? 22  C   X "O4'" 1 
ATOM   268  C  "C3'" . C   A 1 325 ? 166.603 152.880 166.154 1.00 93.44  ? 22  C   X "C3'" 1 
ATOM   269  O  "O3'" . C   A 1 325 ? 167.559 151.846 166.188 1.00 93.44  ? 22  C   X "O3'" 1 
ATOM   270  C  "C2'" . C   A 1 325 ? 166.467 153.620 167.468 1.00 93.44  ? 22  C   X "C2'" 1 
ATOM   271  O  "O2'" . C   A 1 325 ? 167.748 153.908 167.996 1.00 93.44  ? 22  C   X "O2'" 1 
ATOM   272  C  "C1'" . C   A 1 325 ? 165.855 154.936 167.009 1.00 93.44  ? 22  C   X "C1'" 1 
ATOM   273  N  N1    . C   A 1 325 ? 164.388 154.985 167.169 1.00 93.44  ? 22  C   X N1    1 
ATOM   274  C  C2    . C   A 1 325 ? 163.822 154.981 168.438 1.00 93.44  ? 22  C   X C2    1 
ATOM   275  O  O2    . C   A 1 325 ? 164.561 154.901 169.419 1.00 93.44  ? 22  C   X O2    1 
ATOM   276  N  N3    . C   A 1 325 ? 162.486 155.043 168.574 1.00 93.44  ? 22  C   X N3    1 
ATOM   277  C  C4    . C   A 1 325 ? 161.722 155.124 167.499 1.00 93.44  ? 22  C   X C4    1 
ATOM   278  N  N4    . C   A 1 325 ? 160.407 155.194 167.667 1.00 93.44  ? 22  C   X N4    1 
ATOM   279  C  C5    . C   A 1 325 ? 162.261 155.143 166.196 1.00 93.44  ? 22  C   X C5    1 
ATOM   280  C  C6    . C   A 1 325 ? 163.587 155.080 166.081 1.00 93.44  ? 22  C   X C6    1 
ATOM   281  P  P     . C   A 1 326 ? 167.064 150.328 166.190 1.00 101.36 ? 23  C   X P     1 
ATOM   282  O  OP1   . C   A 1 326 ? 168.135 149.472 165.632 1.00 101.36 ? 23  C   X OP1   1 
ATOM   283  O  OP2   . C   A 1 326 ? 165.719 150.330 165.579 1.00 101.36 ? 23  C   X OP2   1 
ATOM   284  O  "O5'" . C   A 1 326 ? 166.902 149.996 167.732 1.00 101.36 ? 23  C   X "O5'" 1 
ATOM   285  C  "C5'" . C   A 1 326 ? 167.749 150.619 168.684 1.00 101.36 ? 23  C   X "C5'" 1 
ATOM   286  C  "C4'" . C   A 1 326 ? 167.260 150.404 170.090 1.00 101.36 ? 23  C   X "C4'" 1 
ATOM   287  O  "O4'" . C   A 1 326 ? 166.134 151.281 170.348 1.00 101.36 ? 23  C   X "O4'" 1 
ATOM   288  C  "C3'" . C   A 1 326 ? 166.790 148.989 170.391 1.00 101.36 ? 23  C   X "C3'" 1 
ATOM   289  O  "O3'" . C   A 1 326 ? 167.226 148.585 171.678 1.00 101.36 ? 23  C   X "O3'" 1 
ATOM   290  C  "C2'" . C   A 1 326 ? 165.276 149.105 170.384 1.00 101.36 ? 23  C   X "C2'" 1 
ATOM   291  O  "O2'" . C   A 1 326 ? 164.630 148.178 171.224 1.00 101.36 ? 23  C   X "O2'" 1 
ATOM   292  C  "C1'" . C   A 1 326 ? 165.054 150.538 170.852 1.00 101.36 ? 23  C   X "C1'" 1 
ATOM   293  N  N1    . C   A 1 326 ? 163.815 151.095 170.310 1.00 101.36 ? 23  C   X N1    1 
ATOM   294  C  C2    . C   A 1 326 ? 162.760 151.371 171.163 1.00 101.36 ? 23  C   X C2    1 
ATOM   295  O  O2    . C   A 1 326 ? 162.912 151.182 172.369 1.00 101.36 ? 23  C   X O2    1 
ATOM   296  N  N3    . C   A 1 326 ? 161.607 151.845 170.657 1.00 101.36 ? 23  C   X N3    1 
ATOM   297  C  C4    . C   A 1 326 ? 161.487 152.031 169.355 1.00 101.36 ? 23  C   X C4    1 
ATOM   298  N  N4    . C   A 1 326 ? 160.330 152.498 168.901 1.00 101.36 ? 23  C   X N4    1 
ATOM   299  C  C5    . C   A 1 326 ? 162.539 151.747 168.458 1.00 101.36 ? 23  C   X C5    1 
ATOM   300  C  C6    . C   A 1 326 ? 163.675 151.278 168.974 1.00 101.36 ? 23  C   X C6    1 
ATOM   301  P  P     . C   A 1 327 ? 167.686 147.065 171.887 1.00 112.56 ? 24  C   X P     1 
ATOM   302  O  OP1   . C   A 1 327 ? 169.140 146.987 171.598 1.00 112.56 ? 24  C   X OP1   1 
ATOM   303  O  OP2   . C   A 1 327 ? 166.743 146.208 171.124 1.00 112.56 ? 24  C   X OP2   1 
ATOM   304  O  "O5'" . C   A 1 327 ? 167.471 146.805 173.442 1.00 112.56 ? 24  C   X "O5'" 1 
ATOM   305  C  "C5'" . C   A 1 327 ? 168.580 146.606 174.301 1.00 112.56 ? 24  C   X "C5'" 1 
ATOM   306  C  "C4'" . C   A 1 327 ? 168.265 147.028 175.711 1.00 112.56 ? 24  C   X "C4'" 1 
ATOM   307  O  "O4'" . C   A 1 327 ? 168.415 148.461 175.846 1.00 112.56 ? 24  C   X "O4'" 1 
ATOM   308  C  "C3'" . C   A 1 327 ? 166.849 146.766 176.184 1.00 112.56 ? 24  C   X "C3'" 1 
ATOM   309  O  "O3'" . C   A 1 327 ? 166.634 145.416 176.561 1.00 112.56 ? 24  C   X "O3'" 1 
ATOM   310  C  "C2'" . C   A 1 327 ? 166.698 147.756 177.335 1.00 112.56 ? 24  C   X "C2'" 1 
ATOM   311  O  "O2'" . C   A 1 327 ? 167.293 147.243 178.517 1.00 112.56 ? 24  C   X "O2'" 1 
ATOM   312  C  "C1'" . C   A 1 327 ? 167.538 148.939 176.842 1.00 112.56 ? 24  C   X "C1'" 1 
ATOM   313  N  N1    . C   A 1 327 ? 166.716 150.032 176.276 1.00 112.56 ? 24  C   X N1    1 
ATOM   314  C  C2    . C   A 1 327 ? 166.656 151.242 176.974 1.00 112.56 ? 24  C   X C2    1 
ATOM   315  O  O2    . C   A 1 327 ? 167.293 151.365 178.029 1.00 112.56 ? 24  C   X O2    1 
ATOM   316  N  N3    . C   A 1 327 ? 165.922 152.260 176.484 1.00 112.56 ? 24  C   X N3    1 
ATOM   317  C  C4    . C   A 1 327 ? 165.251 152.099 175.350 1.00 112.56 ? 24  C   X C4    1 
ATOM   318  N  N4    . C   A 1 327 ? 164.534 153.130 174.909 1.00 112.56 ? 24  C   X N4    1 
ATOM   319  C  C5    . C   A 1 327 ? 165.284 150.878 174.619 1.00 112.56 ? 24  C   X C5    1 
ATOM   320  C  C6    . C   A 1 327 ? 166.022 149.880 175.113 1.00 112.56 ? 24  C   X C6    1 
ATOM   321  P  P     . U   A 1 328 ? 165.530 144.522 175.809 1.00 128.25 ? 25  U   X P     1 
ATOM   322  O  OP1   . U   A 1 328 ? 165.568 143.162 176.390 1.00 128.25 ? 25  U   X OP1   1 
ATOM   323  O  OP2   . U   A 1 328 ? 165.690 144.693 174.347 1.00 128.25 ? 25  U   X OP2   1 
ATOM   324  O  "O5'" . U   A 1 328 ? 164.147 145.168 176.248 1.00 128.25 ? 25  U   X "O5'" 1 
ATOM   325  C  "C5'" . U   A 1 328 ? 163.869 145.395 177.620 1.00 128.25 ? 25  U   X "C5'" 1 
ATOM   326  C  "C4'" . U   A 1 328 ? 162.416 145.718 177.849 1.00 128.25 ? 25  U   X "C4'" 1 
ATOM   327  O  "O4'" . U   A 1 328 ? 162.094 147.019 177.298 1.00 128.25 ? 25  U   X "O4'" 1 
ATOM   328  C  "C3'" . U   A 1 328 ? 161.411 144.788 177.195 1.00 128.25 ? 25  U   X "C3'" 1 
ATOM   329  O  "O3'" . U   A 1 328 ? 161.233 143.582 177.915 1.00 128.25 ? 25  U   X "O3'" 1 
ATOM   330  C  "C2'" . U   A 1 328 ? 160.155 145.645 177.138 1.00 128.25 ? 25  U   X "C2'" 1 
ATOM   331  O  "O2'" . U   A 1 328 ? 159.496 145.650 178.396 1.00 128.25 ? 25  U   X "O2'" 1 
ATOM   332  C  "C1'" . U   A 1 328 ? 160.741 147.040 176.899 1.00 128.25 ? 25  U   X "C1'" 1 
ATOM   333  N  N1    . U   A 1 328 ? 160.634 147.496 175.491 1.00 128.25 ? 25  U   X N1    1 
ATOM   334  C  C2    . U   A 1 328 ? 159.362 147.750 175.026 1.00 128.25 ? 25  U   X C2    1 
ATOM   335  O  O2    . U   A 1 328 ? 158.359 147.590 175.696 1.00 128.25 ? 25  U   X O2    1 
ATOM   336  N  N3    . U   A 1 328 ? 159.257 148.195 173.739 1.00 128.25 ? 25  U   X N3    1 
ATOM   337  C  C4    . U   A 1 328 ? 160.289 148.414 172.867 1.00 128.25 ? 25  U   X C4    1 
ATOM   338  O  O4    . U   A 1 328 ? 160.013 148.815 171.736 1.00 128.25 ? 25  U   X O4    1 
ATOM   339  C  C5    . U   A 1 328 ? 161.584 148.143 173.411 1.00 128.25 ? 25  U   X C5    1 
ATOM   340  C  C6    . U   A 1 328 ? 161.713 147.708 174.670 1.00 128.25 ? 25  U   X C6    1 
ATOM   341  P  P     . U   A 1 329 ? 160.761 142.253 177.149 1.00 140.40 ? 26  U   X P     1 
ATOM   342  O  OP1   . U   A 1 329 ? 160.790 141.135 178.124 1.00 140.40 ? 26  U   X OP1   1 
ATOM   343  O  OP2   . U   A 1 329 ? 161.553 142.153 175.897 1.00 140.40 ? 26  U   X OP2   1 
ATOM   344  O  "O5'" . U   A 1 329 ? 159.235 142.539 176.781 1.00 140.40 ? 26  U   X "O5'" 1 
ATOM   345  C  "C5'" . U   A 1 329 ? 158.259 142.663 177.806 1.00 140.40 ? 26  U   X "C5'" 1 
ATOM   346  C  "C4'" . U   A 1 329 ? 156.858 142.789 177.256 1.00 140.40 ? 26  U   X "C4'" 1 
ATOM   347  O  "O4'" . U   A 1 329 ? 156.632 144.123 176.747 1.00 140.40 ? 26  U   X "O4'" 1 
ATOM   348  C  "C3'" . U   A 1 329 ? 156.493 141.881 176.095 1.00 140.40 ? 26  U   X "C3'" 1 
ATOM   349  O  "O3'" . U   A 1 329 ? 156.174 140.572 176.533 1.00 140.40 ? 26  U   X "O3'" 1 
ATOM   350  C  "C2'" . U   A 1 329 ? 155.328 142.620 175.437 1.00 140.40 ? 26  U   X "C2'" 1 
ATOM   351  O  "O2'" . U   A 1 329 ? 154.102 142.332 176.089 1.00 140.40 ? 26  U   X "O2'" 1 
ATOM   352  C  "C1'" . U   A 1 329 ? 155.689 144.083 175.701 1.00 140.40 ? 26  U   X "C1'" 1 
ATOM   353  N  N1    . U   A 1 329 ? 156.265 144.750 174.521 1.00 140.40 ? 26  U   X N1    1 
ATOM   354  C  C2    . U   A 1 329 ? 155.369 145.354 173.678 1.00 140.40 ? 26  U   X C2    1 
ATOM   355  O  O2    . U   A 1 329 ? 154.170 145.332 173.877 1.00 140.40 ? 26  U   X O2    1 
ATOM   356  N  N3    . U   A 1 329 ? 155.911 145.979 172.594 1.00 140.40 ? 26  U   X N3    1 
ATOM   357  C  C4    . U   A 1 329 ? 157.250 146.050 172.300 1.00 140.40 ? 26  U   X C4    1 
ATOM   358  O  O4    . U   A 1 329 ? 157.598 146.646 171.287 1.00 140.40 ? 26  U   X O4    1 
ATOM   359  C  C5    . U   A 1 329 ? 158.116 145.392 173.227 1.00 140.40 ? 26  U   X C5    1 
ATOM   360  C  C6    . U   A 1 329 ? 157.609 144.781 174.292 1.00 140.40 ? 26  U   X C6    1 
ATOM   361  P  P     . C   A 1 330 ? 155.369 139.552 175.591 1.00 154.94 ? 27  C   X P     1 
ATOM   362  O  OP1   . C   A 1 330 ? 155.547 138.191 176.154 1.00 154.94 ? 27  C   X OP1   1 
ATOM   363  O  OP2   . C   A 1 330 ? 155.742 139.801 174.176 1.00 154.94 ? 27  C   X OP2   1 
ATOM   364  O  "O5'" . C   A 1 330 ? 153.845 139.962 175.800 1.00 154.94 ? 27  C   X "O5'" 1 
ATOM   365  C  "C5'" . C   A 1 330 ? 152.800 139.127 175.328 1.00 154.94 ? 27  C   X "C5'" 1 
ATOM   366  C  "C4'" . C   A 1 330 ? 151.817 139.896 174.486 1.00 154.94 ? 27  C   X "C4'" 1 
ATOM   367  O  "O4'" . C   A 1 330 ? 152.370 141.178 174.116 1.00 154.94 ? 27  C   X "O4'" 1 
ATOM   368  C  "C3'" . C   A 1 330 ? 151.444 139.258 173.162 1.00 154.94 ? 27  C   X "C3'" 1 
ATOM   369  O  "O3'" . C   A 1 330 ? 150.448 138.267 173.318 1.00 154.94 ? 27  C   X "O3'" 1 
ATOM   370  C  "C2'" . C   A 1 330 ? 150.984 140.442 172.320 1.00 154.94 ? 27  C   X "C2'" 1 
ATOM   371  O  "O2'" . C   A 1 330 ? 149.618 140.727 172.563 1.00 154.94 ? 27  C   X "O2'" 1 
ATOM   372  C  "C1'" . C   A 1 330 ? 151.824 141.593 172.884 1.00 154.94 ? 27  C   X "C1'" 1 
ATOM   373  N  N1    . C   A 1 330 ? 152.915 142.031 171.987 1.00 154.94 ? 27  C   X N1    1 
ATOM   374  C  C2    . C   A 1 330 ? 152.605 142.770 170.840 1.00 154.94 ? 27  C   X C2    1 
ATOM   375  O  O2    . C   A 1 330 ? 151.418 143.022 170.588 1.00 154.94 ? 27  C   X O2    1 
ATOM   376  N  N3    . C   A 1 330 ? 153.606 143.182 170.037 1.00 154.94 ? 27  C   X N3    1 
ATOM   377  C  C4    . C   A 1 330 ? 154.865 142.891 170.353 1.00 154.94 ? 27  C   X C4    1 
ATOM   378  N  N4    . C   A 1 330 ? 155.836 143.313 169.540 1.00 154.94 ? 27  C   X N4    1 
ATOM   379  C  C5    . C   A 1 330 ? 155.205 142.157 171.522 1.00 154.94 ? 27  C   X C5    1 
ATOM   380  C  C6    . C   A 1 330 ? 154.206 141.756 172.308 1.00 154.94 ? 27  C   X C6    1 
ATOM   381  P  P     . U   A 1 331 ? 150.342 137.060 172.269 1.00 171.60 ? 28  U   X P     1 
ATOM   382  O  OP1   . U   A 1 331 ? 150.162 137.645 170.919 1.00 171.60 ? 28  U   X OP1   1 
ATOM   383  O  OP2   . U   A 1 331 ? 149.360 136.081 172.792 1.00 171.60 ? 28  U   X OP2   1 
ATOM   384  O  "O5'" . U   A 1 331 ? 151.774 136.371 172.336 1.00 171.60 ? 28  U   X "O5'" 1 
ATOM   385  C  "C5'" . U   A 1 331 ? 152.192 135.438 171.345 1.00 171.60 ? 28  U   X "C5'" 1 
ATOM   386  C  "C4'" . U   A 1 331 ? 153.547 135.809 170.795 1.00 171.60 ? 28  U   X "C4'" 1 
ATOM   387  O  "O4'" . U   A 1 331 ? 153.380 136.351 169.459 1.00 171.60 ? 28  U   X "O4'" 1 
ATOM   388  C  "C3'" . U   A 1 331 ? 154.281 136.873 171.600 1.00 171.60 ? 28  U   X "C3'" 1 
ATOM   389  O  "O3'" . U   A 1 331 ? 155.685 136.642 171.552 1.00 171.60 ? 28  U   X "O3'" 1 
ATOM   390  C  "C2'" . U   A 1 331 ? 153.930 138.164 170.871 1.00 171.60 ? 28  U   X "C2'" 1 
ATOM   391  O  "O2'" . U   A 1 331 ? 154.895 139.182 171.007 1.00 171.60 ? 28  U   X "O2'" 1 
ATOM   392  C  "C1'" . U   A 1 331 ? 153.806 137.701 169.419 1.00 171.60 ? 28  U   X "C1'" 1 
ATOM   393  N  N1    . U   A 1 331 ? 152.791 138.447 168.661 1.00 171.60 ? 28  U   X N1    1 
ATOM   394  C  C2    . U   A 1 331 ? 153.022 139.768 168.331 1.00 171.60 ? 28  U   X C2    1 
ATOM   395  O  O2    . U   A 1 331 ? 154.034 140.374 168.633 1.00 171.60 ? 28  U   X O2    1 
ATOM   396  N  N3    . U   A 1 331 ? 152.000 140.356 167.630 1.00 171.60 ? 28  U   X N3    1 
ATOM   397  C  C4    . U   A 1 331 ? 150.808 139.782 167.230 1.00 171.60 ? 28  U   X C4    1 
ATOM   398  O  O4    . U   A 1 331 ? 149.993 140.453 166.601 1.00 171.60 ? 28  U   X O4    1 
ATOM   399  C  C5    . U   A 1 331 ? 150.644 138.418 167.609 1.00 171.60 ? 28  U   X C5    1 
ATOM   400  C  C6    . U   A 1 331 ? 151.622 137.820 168.289 1.00 171.60 ? 28  U   X C6    1 
ATOM   401  P  P     . G   A 1 332 ? 156.460 136.217 172.893 1.00 189.99 ? 29  G   X P     1 
ATOM   402  O  OP1   . G   A 1 332 ? 155.451 136.055 173.970 1.00 189.99 ? 29  G   X OP1   1 
ATOM   403  O  OP2   . G   A 1 332 ? 157.593 137.153 173.099 1.00 189.99 ? 29  G   X OP2   1 
ATOM   404  O  "O5'" . G   A 1 332 ? 157.051 134.778 172.553 1.00 189.99 ? 29  G   X "O5'" 1 
ATOM   405  C  "C5'" . G   A 1 332 ? 158.188 134.279 173.239 1.00 189.99 ? 29  G   X "C5'" 1 
ATOM   406  C  "C4'" . G   A 1 332 ? 159.106 133.541 172.301 1.00 189.99 ? 29  G   X "C4'" 1 
ATOM   407  O  "O4'" . G   A 1 332 ? 158.551 132.234 171.997 1.00 189.99 ? 29  G   X "O4'" 1 
ATOM   408  C  "C3'" . G   A 1 332 ? 159.307 134.181 170.937 1.00 189.99 ? 29  G   X "C3'" 1 
ATOM   409  O  "O3'" . G   A 1 332 ? 160.248 135.241 170.943 1.00 189.99 ? 29  G   X "O3'" 1 
ATOM   410  C  "C2'" . G   A 1 332 ? 159.715 132.997 170.073 1.00 189.99 ? 29  G   X "C2'" 1 
ATOM   411  O  "O2'" . G   A 1 332 ? 161.075 132.656 170.300 1.00 189.99 ? 29  G   X "O2'" 1 
ATOM   412  C  "C1'" . G   A 1 332 ? 158.835 131.890 170.656 1.00 189.99 ? 29  G   X "C1'" 1 
ATOM   413  N  N9    . G   A 1 332 ? 157.558 131.770 169.927 1.00 189.99 ? 29  G   X N9    1 
ATOM   414  C  C8    . G   A 1 332 ? 156.363 132.363 170.258 1.00 189.99 ? 29  G   X C8    1 
ATOM   415  N  N7    . G   A 1 332 ? 155.401 132.079 169.423 1.00 189.99 ? 29  G   X N7    1 
ATOM   416  C  C5    . G   A 1 332 ? 155.995 131.250 168.481 1.00 189.99 ? 29  G   X C5    1 
ATOM   417  C  C6    . G   A 1 332 ? 155.448 130.622 167.331 1.00 189.99 ? 29  G   X C6    1 
ATOM   418  O  O6    . G   A 1 332 ? 154.289 130.674 166.898 1.00 189.99 ? 29  G   X O6    1 
ATOM   419  N  N1    . G   A 1 332 ? 156.403 129.868 166.657 1.00 189.99 ? 29  G   X N1    1 
ATOM   420  C  C2    . G   A 1 332 ? 157.715 129.731 167.036 1.00 189.99 ? 29  G   X C2    1 
ATOM   421  N  N2    . G   A 1 332 ? 158.479 128.958 166.251 1.00 189.99 ? 29  G   X N2    1 
ATOM   422  N  N3    . G   A 1 332 ? 158.238 130.312 168.105 1.00 189.99 ? 29  G   X N3    1 
ATOM   423  C  C4    . G   A 1 332 ? 157.328 131.051 168.777 1.00 189.99 ? 29  G   X C4    1 
ATOM   424  P  P     . C   A 1 333 ? 159.988 136.544 170.040 1.00 188.59 ? 30  C   X P     1 
ATOM   425  O  OP1   . C   A 1 333 ? 161.279 137.260 169.867 1.00 188.59 ? 30  C   X OP1   1 
ATOM   426  O  OP2   . C   A 1 333 ? 158.817 137.262 170.602 1.00 188.59 ? 30  C   X OP2   1 
ATOM   427  O  "O5'" . C   A 1 333 ? 159.548 135.941 168.632 1.00 188.59 ? 30  C   X "O5'" 1 
ATOM   428  C  "C5'" . C   A 1 333 ? 159.227 136.781 167.533 1.00 188.59 ? 30  C   X "C5'" 1 
ATOM   429  C  "C4'" . C   A 1 333 ? 159.334 136.029 166.230 1.00 188.59 ? 30  C   X "C4'" 1 
ATOM   430  O  "O4'" . C   A 1 333 ? 158.365 134.949 166.199 1.00 188.59 ? 30  C   X "O4'" 1 
ATOM   431  C  "C3'" . C   A 1 333 ? 159.039 136.822 164.969 1.00 188.59 ? 30  C   X "C3'" 1 
ATOM   432  O  "O3'" . C   A 1 333 ? 160.132 137.623 164.553 1.00 188.59 ? 30  C   X "O3'" 1 
ATOM   433  C  "C2'" . C   A 1 333 ? 158.665 135.730 163.974 1.00 188.59 ? 30  C   X "C2'" 1 
ATOM   434  O  "O2'" . C   A 1 333 ? 159.829 135.092 163.467 1.00 188.59 ? 30  C   X "O2'" 1 
ATOM   435  C  "C1'" . C   A 1 333 ? 157.925 134.737 164.874 1.00 188.59 ? 30  C   X "C1'" 1 
ATOM   436  N  N1    . C   A 1 333 ? 156.453 134.909 164.819 1.00 188.59 ? 30  C   X N1    1 
ATOM   437  C  C2    . C   A 1 333 ? 155.757 134.455 163.692 1.00 188.59 ? 30  C   X C2    1 
ATOM   438  O  O2    . C   A 1 333 ? 156.392 133.923 162.768 1.00 188.59 ? 30  C   X O2    1 
ATOM   439  N  N3    . C   A 1 333 ? 154.409 134.607 163.634 1.00 188.59 ? 30  C   X N3    1 
ATOM   440  C  C4    . C   A 1 333 ? 153.754 135.177 164.647 1.00 188.59 ? 30  C   X C4    1 
ATOM   441  N  N4    . C   A 1 333 ? 152.429 135.315 164.546 1.00 188.59 ? 30  C   X N4    1 
ATOM   442  C  C5    . C   A 1 333 ? 154.438 135.649 165.805 1.00 188.59 ? 30  C   X C5    1 
ATOM   443  C  C6    . C   A 1 333 ? 155.769 135.494 165.850 1.00 188.59 ? 30  C   X C6    1 
ATOM   444  P  P     . G   A 1 334 ? 159.903 139.169 164.170 1.00 179.52 ? 31  G   X P     1 
ATOM   445  O  OP1   . G   A 1 334 ? 161.229 139.809 163.971 1.00 179.52 ? 31  G   X OP1   1 
ATOM   446  O  OP2   . G   A 1 334 ? 158.967 139.740 165.172 1.00 179.52 ? 31  G   X OP2   1 
ATOM   447  O  "O5'" . G   A 1 334 ? 159.164 139.106 162.758 1.00 179.52 ? 31  G   X "O5'" 1 
ATOM   448  C  "C5'" . G   A 1 334 ? 158.500 140.242 162.222 1.00 179.52 ? 31  G   X "C5'" 1 
ATOM   449  C  "C4'" . G   A 1 334 ? 157.520 139.852 161.141 1.00 179.52 ? 31  G   X "C4'" 1 
ATOM   450  O  "O4'" . G   A 1 334 ? 156.692 138.761 161.602 1.00 179.52 ? 31  G   X "O4'" 1 
ATOM   451  C  "C3'" . G   A 1 334 ? 156.533 140.930 160.719 1.00 179.52 ? 31  G   X "C3'" 1 
ATOM   452  O  "O3'" . G   A 1 334 ? 157.079 141.794 159.737 1.00 179.52 ? 31  G   X "O3'" 1 
ATOM   453  C  "C2'" . G   A 1 334 ? 155.325 140.140 160.212 1.00 179.52 ? 31  G   X "C2'" 1 
ATOM   454  O  "O2'" . G   A 1 334 ? 155.470 139.835 158.834 1.00 179.52 ? 31  G   X "O2'" 1 
ATOM   455  C  "C1'" . G   A 1 334 ? 155.417 138.836 161.009 1.00 179.52 ? 31  G   X "C1'" 1 
ATOM   456  N  N9    . G   A 1 334 ? 154.374 138.641 162.042 1.00 179.52 ? 31  G   X N9    1 
ATOM   457  C  C8    . G   A 1 334 ? 154.630 138.108 163.282 1.00 179.52 ? 31  G   X C8    1 
ATOM   458  N  N7    . G   A 1 334 ? 153.576 137.976 164.028 1.00 179.52 ? 31  G   X N7    1 
ATOM   459  C  C5    . G   A 1 334 ? 152.546 138.408 163.228 1.00 179.52 ? 31  G   X C5    1 
ATOM   460  C  C6    . G   A 1 334 ? 151.170 138.479 163.530 1.00 179.52 ? 31  G   X C6    1 
ATOM   461  O  O6    . G   A 1 334 ? 150.607 138.158 164.580 1.00 179.52 ? 31  G   X O6    1 
ATOM   462  N  N1    . G   A 1 334 ? 150.438 138.983 162.465 1.00 179.52 ? 31  G   X N1    1 
ATOM   463  C  C2    . G   A 1 334 ? 150.971 139.367 161.265 1.00 179.52 ? 31  G   X C2    1 
ATOM   464  N  N2    . G   A 1 334 ? 150.085 139.825 160.371 1.00 179.52 ? 31  G   X N2    1 
ATOM   465  N  N3    . G   A 1 334 ? 152.264 139.307 160.968 1.00 179.52 ? 31  G   X N3    1 
ATOM   466  C  C4    . G   A 1 334 ? 153.002 138.819 161.992 1.00 179.52 ? 31  G   X C4    1 
ATOM   467  P  P     . U   A 1 335 ? 157.031 143.389 159.924 1.00 173.09 ? 32  U   X P     1 
ATOM   468  O  OP1   . U   A 1 335 ? 157.363 144.010 158.616 1.00 173.09 ? 32  U   X OP1   1 
ATOM   469  O  OP2   . U   A 1 335 ? 157.817 143.737 161.134 1.00 173.09 ? 32  U   X OP2   1 
ATOM   470  O  "O5'" . U   A 1 335 ? 155.502 143.694 160.236 1.00 173.09 ? 32  U   X "O5'" 1 
ATOM   471  C  "C5'" . U   A 1 335 ? 154.499 143.537 159.245 1.00 173.09 ? 32  U   X "C5'" 1 
ATOM   472  C  "C4'" . U   A 1 335 ? 153.135 143.670 159.862 1.00 173.09 ? 32  U   X "C4'" 1 
ATOM   473  O  "O4'" . U   A 1 335 ? 152.768 142.422 160.500 1.00 173.09 ? 32  U   X "O4'" 1 
ATOM   474  C  "C3'" . U   A 1 335 ? 153.047 144.701 160.973 1.00 173.09 ? 32  U   X "C3'" 1 
ATOM   475  O  "O3'" . U   A 1 335 ? 152.855 146.014 160.479 1.00 173.09 ? 32  U   X "O3'" 1 
ATOM   476  C  "C2'" . U   A 1 335 ? 151.897 144.188 161.831 1.00 173.09 ? 32  U   X "C2'" 1 
ATOM   477  O  "O2'" . U   A 1 335 ? 150.646 144.574 161.283 1.00 173.09 ? 32  U   X "O2'" 1 
ATOM   478  C  "C1'" . U   A 1 335 ? 152.049 142.676 161.687 1.00 173.09 ? 32  U   X "C1'" 1 
ATOM   479  N  N1    . U   A 1 335 ? 152.778 142.058 162.817 1.00 173.09 ? 32  U   X N1    1 
ATOM   480  C  C2    . U   A 1 335 ? 152.036 141.560 163.859 1.00 173.09 ? 32  U   X C2    1 
ATOM   481  O  O2    . U   A 1 335 ? 150.819 141.620 163.885 1.00 173.09 ? 32  U   X O2    1 
ATOM   482  N  N3    . U   A 1 335 ? 152.772 140.984 164.865 1.00 173.09 ? 32  U   X N3    1 
ATOM   483  C  C4    . U   A 1 335 ? 154.141 140.863 164.935 1.00 173.09 ? 32  U   X C4    1 
ATOM   484  O  O4    . U   A 1 335 ? 154.658 140.318 165.908 1.00 173.09 ? 32  U   X O4    1 
ATOM   485  C  C5    . U   A 1 335 ? 154.836 141.405 163.818 1.00 173.09 ? 32  U   X C5    1 
ATOM   486  C  C6    . U   A 1 335 ? 154.144 141.967 162.828 1.00 173.09 ? 32  U   X C6    1 
ATOM   487  P  P     . G   A 1 336 ? 154.064 147.073 160.489 1.00 159.40 ? 33  G   X P     1 
ATOM   488  O  OP1   . G   A 1 336 ? 154.255 147.571 159.106 1.00 159.40 ? 33  G   X OP1   1 
ATOM   489  O  OP2   . G   A 1 336 ? 155.207 146.457 161.206 1.00 159.40 ? 33  G   X OP2   1 
ATOM   490  O  "O5'" . G   A 1 336 ? 153.499 148.282 161.356 1.00 159.40 ? 33  G   X "O5'" 1 
ATOM   491  C  "C5'" . G   A 1 336 ? 152.293 148.932 160.990 1.00 159.40 ? 33  G   X "C5'" 1 
ATOM   492  C  "C4'" . G   A 1 336 ? 151.180 148.607 161.952 1.00 159.40 ? 33  G   X "C4'" 1 
ATOM   493  O  "O4'" . G   A 1 336 ? 151.194 147.185 162.245 1.00 159.40 ? 33  G   X "O4'" 1 
ATOM   494  C  "C3'" . G   A 1 336 ? 151.276 149.263 163.320 1.00 159.40 ? 33  G   X "C3'" 1 
ATOM   495  O  "O3'" . G   A 1 336 ? 150.782 150.587 163.341 1.00 159.40 ? 33  G   X "O3'" 1 
ATOM   496  C  "C2'" . G   A 1 336 ? 150.480 148.311 164.191 1.00 159.40 ? 33  G   X "C2'" 1 
ATOM   497  O  "O2'" . G   A 1 336 ? 149.089 148.487 163.972 1.00 159.40 ? 33  G   X "O2'" 1 
ATOM   498  C  "C1'" . G   A 1 336 ? 150.889 146.969 163.605 1.00 159.40 ? 33  G   X "C1'" 1 
ATOM   499  N  N9    . G   A 1 336 ? 152.095 146.435 164.268 1.00 159.40 ? 33  G   X N9    1 
ATOM   500  C  C8    . G   A 1 336 ? 153.389 146.571 163.827 1.00 159.40 ? 33  G   X C8    1 
ATOM   501  N  N7    . G   A 1 336 ? 154.269 146.007 164.598 1.00 159.40 ? 33  G   X N7    1 
ATOM   502  C  C5    . G   A 1 336 ? 153.513 145.468 165.617 1.00 159.40 ? 33  G   X C5    1 
ATOM   503  C  C6    . G   A 1 336 ? 153.936 144.735 166.743 1.00 159.40 ? 33  G   X C6    1 
ATOM   504  O  O6    . G   A 1 336 ? 155.090 144.424 167.049 1.00 159.40 ? 33  G   X O6    1 
ATOM   505  N  N1    . G   A 1 336 ? 152.861 144.372 167.533 1.00 159.40 ? 33  G   X N1    1 
ATOM   506  C  C2    . G   A 1 336 ? 151.547 144.667 167.271 1.00 159.40 ? 33  G   X C2    1 
ATOM   507  N  N2    . G   A 1 336 ? 150.653 144.221 168.158 1.00 159.40 ? 33  G   X N2    1 
ATOM   508  N  N3    . G   A 1 336 ? 151.138 145.350 166.220 1.00 159.40 ? 33  G   X N3    1 
ATOM   509  C  C4    . G   A 1 336 ? 152.171 145.718 165.439 1.00 159.40 ? 33  G   X C4    1 
ATOM   510  P  P     . A   A 1 337 ? 151.297 151.610 164.465 1.00 149.22 ? 34  A   X P     1 
ATOM   511  O  OP1   . A   A 1 337 ? 150.645 152.921 164.221 1.00 149.22 ? 34  A   X OP1   1 
ATOM   512  O  OP2   . A   A 1 337 ? 152.777 151.512 164.503 1.00 149.22 ? 34  A   X OP2   1 
ATOM   513  O  "O5'" . A   A 1 337 ? 150.735 151.018 165.835 1.00 149.22 ? 34  A   X "O5'" 1 
ATOM   514  C  "C5'" . A   A 1 337 ? 149.350 151.070 166.144 1.00 149.22 ? 34  A   X "C5'" 1 
ATOM   515  C  "C4'" . A   A 1 337 ? 148.994 150.100 167.241 1.00 149.22 ? 34  A   X "C4'" 1 
ATOM   516  O  "O4'" . A   A 1 337 ? 149.592 148.811 166.965 1.00 149.22 ? 34  A   X "O4'" 1 
ATOM   517  C  "C3'" . A   A 1 337 ? 149.492 150.454 168.630 1.00 149.22 ? 34  A   X "C3'" 1 
ATOM   518  O  "O3'" . A   A 1 337 ? 148.624 151.358 169.291 1.00 149.22 ? 34  A   X "O3'" 1 
ATOM   519  C  "C2'" . A   A 1 337 ? 149.571 149.097 169.312 1.00 149.22 ? 34  A   X "C2'" 1 
ATOM   520  O  "O2'" . A   A 1 337 ? 148.279 148.678 169.719 1.00 149.22 ? 34  A   X "O2'" 1 
ATOM   521  C  "C1'" . A   A 1 337 ? 150.012 148.203 168.161 1.00 149.22 ? 34  A   X "C1'" 1 
ATOM   522  N  N9    . A   A 1 337 ? 151.473 148.033 168.105 1.00 149.22 ? 34  A   X N9    1 
ATOM   523  C  C8    . A   A 1 337 ? 152.335 148.518 167.157 1.00 149.22 ? 34  A   X C8    1 
ATOM   524  N  N7    . A   A 1 337 ? 153.587 148.188 167.364 1.00 149.22 ? 34  A   X N7    1 
ATOM   525  C  C5    . A   A 1 337 ? 153.545 147.428 168.526 1.00 149.22 ? 34  A   X C5    1 
ATOM   526  C  C6    . A   A 1 337 ? 154.541 146.781 169.282 1.00 149.22 ? 34  A   X C6    1 
ATOM   527  N  N6    . A   A 1 337 ? 155.833 146.791 168.966 1.00 149.22 ? 34  A   X N6    1 
ATOM   528  N  N1    . A   A 1 337 ? 154.167 146.113 170.390 1.00 149.22 ? 34  A   X N1    1 
ATOM   529  C  C2    . A   A 1 337 ? 152.871 146.102 170.705 1.00 149.22 ? 34  A   X C2    1 
ATOM   530  N  N3    . A   A 1 337 ? 151.844 146.667 170.081 1.00 149.22 ? 34  A   X N3    1 
ATOM   531  C  C4    . A   A 1 337 ? 152.249 147.324 168.987 1.00 149.22 ? 34  A   X C4    1 
ATOM   532  P  P     . A   A 1 338 ? 149.202 152.480 170.283 1.00 131.81 ? 35  A   X P     1 
ATOM   533  O  OP1   . A   A 1 338 ? 148.041 153.264 170.763 1.00 131.81 ? 35  A   X OP1   1 
ATOM   534  O  OP2   . A   A 1 338 ? 150.347 153.153 169.623 1.00 131.81 ? 35  A   X OP2   1 
ATOM   535  O  "O5'" . A   A 1 338 ? 149.776 151.659 171.517 1.00 131.81 ? 35  A   X "O5'" 1 
ATOM   536  C  "C5'" . A   A 1 338 ? 148.904 151.113 172.490 1.00 131.81 ? 35  A   X "C5'" 1 
ATOM   537  C  "C4'" . A   A 1 338 ? 149.670 150.364 173.546 1.00 131.81 ? 35  A   X "C4'" 1 
ATOM   538  O  "O4'" . A   A 1 338 ? 150.345 149.230 172.943 1.00 131.81 ? 35  A   X "O4'" 1 
ATOM   539  C  "C3'" . A   A 1 338 ? 150.798 151.119 174.237 1.00 131.81 ? 35  A   X "C3'" 1 
ATOM   540  O  "O3'" . A   A 1 338 ? 150.369 152.022 175.246 1.00 131.81 ? 35  A   X "O3'" 1 
ATOM   541  C  "C2'" . A   A 1 338 ? 151.650 149.982 174.769 1.00 131.81 ? 35  A   X "C2'" 1 
ATOM   542  O  "O2'" . A   A 1 338 ? 151.026 149.380 175.891 1.00 131.81 ? 35  A   X "O2'" 1 
ATOM   543  C  "C1'" . A   A 1 338 ? 151.566 148.994 173.613 1.00 131.81 ? 35  A   X "C1'" 1 
ATOM   544  N  N9    . A   A 1 338 ? 152.689 149.157 172.670 1.00 131.81 ? 35  A   X N9    1 
ATOM   545  C  C8    . A   A 1 338 ? 152.665 149.368 171.323 1.00 131.81 ? 35  A   X C8    1 
ATOM   546  N  N7    . A   A 1 338 ? 153.860 149.460 170.785 1.00 131.81 ? 35  A   X N7    1 
ATOM   547  C  C5    . A   A 1 338 ? 154.732 149.301 171.844 1.00 131.81 ? 35  A   X C5    1 
ATOM   548  C  C6    . A   A 1 338 ? 156.135 149.290 171.952 1.00 131.81 ? 35  A   X C6    1 
ATOM   549  N  N6    . A   A 1 338 ? 156.989 149.454 170.946 1.00 131.81 ? 35  A   X N6    1 
ATOM   550  N  N1    . A   A 1 338 ? 156.677 149.104 173.168 1.00 131.81 ? 35  A   X N1    1 
ATOM   551  C  C2    . A   A 1 338 ? 155.848 148.940 174.195 1.00 131.81 ? 35  A   X C2    1 
ATOM   552  N  N3    . A   A 1 338 ? 154.526 148.926 174.225 1.00 131.81 ? 35  A   X N3    1 
ATOM   553  C  C4    . A   A 1 338 ? 154.017 149.113 173.004 1.00 131.81 ? 35  A   X C4    1 
ATOM   554  P  P     . G   A 1 339 ? 151.162 153.401 175.509 1.00 112.66 ? 36  G   X P     1 
ATOM   555  O  OP1   . G   A 1 339 ? 150.514 154.049 176.668 1.00 112.66 ? 36  G   X OP1   1 
ATOM   556  O  OP2   . G   A 1 339 ? 151.296 154.154 174.240 1.00 112.66 ? 36  G   X OP2   1 
ATOM   557  O  "O5'" . G   A 1 339 ? 152.619 152.958 175.970 1.00 112.66 ? 36  G   X "O5'" 1 
ATOM   558  C  "C5'" . G   A 1 339 ? 152.945 152.886 177.347 1.00 112.66 ? 36  G   X "C5'" 1 
ATOM   559  C  "C4'" . G   A 1 339 ? 154.429 152.741 177.583 1.00 112.66 ? 36  G   X "C4'" 1 
ATOM   560  O  "O4'" . G   A 1 339 ? 154.958 151.644 176.798 1.00 112.66 ? 36  G   X "O4'" 1 
ATOM   561  C  "C3'" . G   A 1 339 ? 155.309 153.916 177.195 1.00 112.66 ? 36  G   X "C3'" 1 
ATOM   562  O  "O3'" . G   A 1 339 ? 155.299 154.963 178.146 1.00 112.66 ? 36  G   X "O3'" 1 
ATOM   563  C  "C2'" . G   A 1 339 ? 156.668 153.257 177.061 1.00 112.66 ? 36  G   X "C2'" 1 
ATOM   564  O  "O2'" . G   A 1 339 ? 157.207 152.995 178.343 1.00 112.66 ? 36  G   X "O2'" 1 
ATOM   565  C  "C1'" . G   A 1 339 ? 156.289 151.928 176.424 1.00 112.66 ? 36  G   X "C1'" 1 
ATOM   566  N  N9    . G   A 1 339 ? 156.368 152.021 174.959 1.00 112.66 ? 36  G   X N9    1 
ATOM   567  C  C8    . G   A 1 339 ? 155.343 152.118 174.060 1.00 112.66 ? 36  G   X C8    1 
ATOM   568  N  N7    . G   A 1 339 ? 155.759 152.194 172.828 1.00 112.66 ? 36  G   X N7    1 
ATOM   569  C  C5    . G   A 1 339 ? 157.139 152.164 172.928 1.00 112.66 ? 36  G   X C5    1 
ATOM   570  C  C6    . G   A 1 339 ? 158.134 152.216 171.928 1.00 112.66 ? 36  G   X C6    1 
ATOM   571  O  O6    . G   A 1 339 ? 157.998 152.309 170.705 1.00 112.66 ? 36  G   X O6    1 
ATOM   572  N  N1    . G   A 1 339 ? 159.408 152.154 172.467 1.00 112.66 ? 36  G   X N1    1 
ATOM   573  C  C2    . G   A 1 339 ? 159.689 152.047 173.798 1.00 112.66 ? 36  G   X C2    1 
ATOM   574  N  N2    . G   A 1 339 ? 160.983 152.003 174.127 1.00 112.66 ? 36  G   X N2    1 
ATOM   575  N  N3    . G   A 1 339 ? 158.772 151.998 174.743 1.00 112.66 ? 36  G   X N3    1 
ATOM   576  C  C4    . G   A 1 339 ? 157.528 152.057 174.237 1.00 112.66 ? 36  G   X C4    1 
ATOM   577  P  P     . G   A 1 340 ? 155.822 156.434 177.755 1.00 102.88 ? 37  G   X P     1 
ATOM   578  O  OP1   . G   A 1 340 ? 155.625 157.302 178.937 1.00 102.88 ? 37  G   X OP1   1 
ATOM   579  O  OP2   . G   A 1 340 ? 155.228 156.832 176.458 1.00 102.88 ? 37  G   X OP2   1 
ATOM   580  O  "O5'" . G   A 1 340 ? 157.391 156.264 177.543 1.00 102.88 ? 37  G   X "O5'" 1 
ATOM   581  C  "C5'" . G   A 1 340 ? 158.264 156.056 178.641 1.00 102.88 ? 37  G   X "C5'" 1 
ATOM   582  C  "C4'" . G   A 1 340 ? 159.671 155.776 178.178 1.00 102.88 ? 37  G   X "C4'" 1 
ATOM   583  O  "O4'" . G   A 1 340 ? 159.671 154.690 177.218 1.00 102.88 ? 37  G   X "O4'" 1 
ATOM   584  C  "C3'" . G   A 1 340 ? 160.372 156.899 177.441 1.00 102.88 ? 37  G   X "C3'" 1 
ATOM   585  O  "O3'" . G   A 1 340 ? 160.896 157.885 178.303 1.00 102.88 ? 37  G   X "O3'" 1 
ATOM   586  C  "C2'" . G   A 1 340 ? 161.443 156.158 176.666 1.00 102.88 ? 37  G   X "C2'" 1 
ATOM   587  O  "O2'" . G   A 1 340 ? 162.510 155.802 177.527 1.00 102.88 ? 37  G   X "O2'" 1 
ATOM   588  C  "C1'" . G   A 1 340 ? 160.703 154.886 176.278 1.00 102.88 ? 37  G   X "C1'" 1 
ATOM   589  N  N9    . G   A 1 340 ? 160.106 154.982 174.937 1.00 102.88 ? 37  G   X N9    1 
ATOM   590  C  C8    . G   A 1 340 ? 158.777 154.924 174.645 1.00 102.88 ? 37  G   X C8    1 
ATOM   591  N  N7    . G   A 1 340 ? 158.523 155.015 173.373 1.00 102.88 ? 37  G   X N7    1 
ATOM   592  C  C5    . G   A 1 340 ? 159.766 155.160 172.789 1.00 102.88 ? 37  G   X C5    1 
ATOM   593  C  C6    . G   A 1 340 ? 160.115 155.311 171.433 1.00 102.88 ? 37  G   X C6    1 
ATOM   594  O  O6    . G   A 1 340 ? 159.376 155.352 170.450 1.00 102.88 ? 37  G   X O6    1 
ATOM   595  N  N1    . G   A 1 340 ? 161.485 155.419 171.266 1.00 102.88 ? 37  G   X N1    1 
ATOM   596  C  C2    . G   A 1 340 ? 162.395 155.381 172.282 1.00 102.88 ? 37  G   X C2    1 
ATOM   597  N  N2    . G   A 1 340 ? 163.673 155.504 171.928 1.00 102.88 ? 37  G   X N2    1 
ATOM   598  N  N3    . G   A 1 340 ? 162.084 155.244 173.554 1.00 102.88 ? 37  G   X N3    1 
ATOM   599  C  C4    . G   A 1 340 ? 160.757 155.136 173.736 1.00 102.88 ? 37  G   X C4    1 
ATOM   600  P  P     . C   A 1 341 ? 161.160 159.363 177.745 1.00 93.49  ? 38  C   X P     1 
ATOM   601  O  OP1   . C   A 1 341 ? 161.715 160.196 178.839 1.00 93.49  ? 38  C   X OP1   1 
ATOM   602  O  OP2   . C   A 1 341 ? 159.945 159.799 177.019 1.00 93.49  ? 38  C   X OP2   1 
ATOM   603  O  "O5'" . C   A 1 341 ? 162.304 159.154 176.666 1.00 93.49  ? 38  C   X "O5'" 1 
ATOM   604  C  "C5'" . C   A 1 341 ? 163.628 158.838 177.055 1.00 93.49  ? 38  C   X "C5'" 1 
ATOM   605  C  "C4'" . C   A 1 341 ? 164.592 159.240 175.978 1.00 93.49  ? 38  C   X "C4'" 1 
ATOM   606  O  "O4'" . C   A 1 341 ? 164.501 158.315 174.868 1.00 93.49  ? 38  C   X "O4'" 1 
ATOM   607  C  "C3'" . C   A 1 341 ? 164.312 160.588 175.352 1.00 93.49  ? 38  C   X "C3'" 1 
ATOM   608  O  "O3'" . C   A 1 341 ? 164.815 161.654 176.124 1.00 93.49  ? 38  C   X "O3'" 1 
ATOM   609  C  "C2'" . C   A 1 341 ? 164.959 160.459 173.987 1.00 93.49  ? 38  C   X "C2'" 1 
ATOM   610  O  "O2'" . C   A 1 341 ? 166.364 160.581 174.101 1.00 93.49  ? 38  C   X "O2'" 1 
ATOM   611  C  "C1'" . C   A 1 341 ? 164.655 159.009 173.651 1.00 93.49  ? 38  C   X "C1'" 1 
ATOM   612  N  N1    . C   A 1 341 ? 163.418 158.841 172.863 1.00 93.49  ? 38  C   X N1    1 
ATOM   613  C  C2    . C   A 1 341 ? 163.414 158.998 171.481 1.00 93.49  ? 38  C   X C2    1 
ATOM   614  O  O2    . C   A 1 341 ? 164.446 159.311 170.888 1.00 93.49  ? 38  C   X O2    1 
ATOM   615  N  N3    . C   A 1 341 ? 162.275 158.807 170.795 1.00 93.49  ? 38  C   X N3    1 
ATOM   616  C  C4    . C   A 1 341 ? 161.169 158.465 171.436 1.00 93.49  ? 38  C   X C4    1 
ATOM   617  N  N4    . C   A 1 341 ? 160.053 158.281 170.736 1.00 93.49  ? 38  C   X N4    1 
ATOM   618  C  C5    . C   A 1 341 ? 161.141 158.290 172.836 1.00 93.49  ? 38  C   X C5    1 
ATOM   619  C  C6    . C   A 1 341 ? 162.279 158.478 173.498 1.00 93.49  ? 38  C   X C6    1 
ATOM   620  P  P     . U   A 1 342 ? 164.043 163.052 176.153 1.00 87.14  ? 39  U   X P     1 
ATOM   621  O  OP1   . U   A 1 342 ? 164.445 163.795 177.368 1.00 87.14  ? 39  U   X OP1   1 
ATOM   622  O  OP2   . U   A 1 342 ? 162.617 162.787 175.882 1.00 87.14  ? 39  U   X OP2   1 
ATOM   623  O  "O5'" . U   A 1 342 ? 164.639 163.819 174.904 1.00 87.14  ? 39  U   X "O5'" 1 
ATOM   624  C  "C5'" . U   A 1 342 ? 166.020 163.738 174.610 1.00 87.14  ? 39  U   X "C5'" 1 
ATOM   625  C  "C4'" . U   A 1 342 ? 166.286 164.124 173.185 1.00 87.14  ? 39  U   X "C4'" 1 
ATOM   626  O  "O4'" . U   A 1 342 ? 165.910 163.055 172.298 1.00 87.14  ? 39  U   X "O4'" 1 
ATOM   627  C  "C3'" . U   A 1 342 ? 165.495 165.310 172.687 1.00 87.14  ? 39  U   X "C3'" 1 
ATOM   628  O  "O3'" . U   A 1 342 ? 166.102 166.521 173.075 1.00 87.14  ? 39  U   X "O3'" 1 
ATOM   629  C  "C2'" . U   A 1 342 ? 165.483 165.104 171.183 1.00 87.14  ? 39  U   X "C2'" 1 
ATOM   630  O  "O2'" . U   A 1 342 ? 166.690 165.580 170.617 1.00 87.14  ? 39  U   X "O2'" 1 
ATOM   631  C  "C1'" . U   A 1 342 ? 165.478 163.585 171.072 1.00 87.14  ? 39  U   X "C1'" 1 
ATOM   632  N  N1    . U   A 1 342 ? 164.158 163.018 170.758 1.00 87.14  ? 39  U   X N1    1 
ATOM   633  C  C2    . U   A 1 342 ? 163.866 162.849 169.440 1.00 87.14  ? 39  U   X C2    1 
ATOM   634  O  O2    . U   A 1 342 ? 164.628 163.175 168.561 1.00 87.14  ? 39  U   X O2    1 
ATOM   635  N  N3    . U   A 1 342 ? 162.654 162.288 169.185 1.00 87.14  ? 39  U   X N3    1 
ATOM   636  C  C4    . U   A 1 342 ? 161.725 161.882 170.102 1.00 87.14  ? 39  U   X C4    1 
ATOM   637  O  O4    . U   A 1 342 ? 160.668 161.393 169.713 1.00 87.14  ? 39  U   X O4    1 
ATOM   638  C  C5    . U   A 1 342 ? 162.111 162.084 171.455 1.00 87.14  ? 39  U   X C5    1 
ATOM   639  C  C6    . U   A 1 342 ? 163.293 162.630 171.729 1.00 87.14  ? 39  U   X C6    1 
ATOM   640  P  P     . G   A 1 343 ? 165.203 167.778 173.464 1.00 86.24  ? 40  G   X P     1 
ATOM   641  O  OP1   . G   A 1 343 ? 166.003 168.673 174.335 1.00 86.24  ? 40  G   X OP1   1 
ATOM   642  O  OP2   . G   A 1 343 ? 163.881 167.276 173.896 1.00 86.24  ? 40  G   X OP2   1 
ATOM   643  O  "O5'" . G   A 1 343 ? 164.973 168.492 172.073 1.00 86.24  ? 40  G   X "O5'" 1 
ATOM   644  C  "C5'" . G   A 1 343 ? 163.663 168.808 171.658 1.00 86.24  ? 40  G   X "C5'" 1 
ATOM   645  C  "C4'" . G   A 1 343 ? 163.466 168.520 170.201 1.00 86.24  ? 40  G   X "C4'" 1 
ATOM   646  O  "O4'" . G   A 1 343 ? 163.453 167.091 169.979 1.00 86.24  ? 40  G   X "O4'" 1 
ATOM   647  C  "C3'" . G   A 1 343 ? 162.145 168.980 169.635 1.00 86.24  ? 40  G   X "C3'" 1 
ATOM   648  O  "O3'" . G   A 1 343 ? 162.137 170.361 169.345 1.00 86.24  ? 40  G   X "O3'" 1 
ATOM   649  C  "C2'" . G   A 1 343 ? 161.996 168.091 168.420 1.00 86.24  ? 40  G   X "C2'" 1 
ATOM   650  O  "O2'" . G   A 1 343 ? 162.872 168.525 167.397 1.00 86.24  ? 40  G   X "O2'" 1 
ATOM   651  C  "C1'" . G   A 1 343 ? 162.531 166.774 168.964 1.00 86.24  ? 40  G   X "C1'" 1 
ATOM   652  N  N9    . G   A 1 343 ? 161.458 165.962 169.560 1.00 86.24  ? 40  G   X N9    1 
ATOM   653  C  C8    . G   A 1 343 ? 161.265 165.703 170.885 1.00 86.24  ? 40  G   X C8    1 
ATOM   654  N  N7    . G   A 1 343 ? 160.228 164.962 171.127 1.00 86.24  ? 40  G   X N7    1 
ATOM   655  C  C5    . G   A 1 343 ? 159.703 164.719 169.880 1.00 86.24  ? 40  G   X C5    1 
ATOM   656  C  C6    . G   A 1 343 ? 158.570 163.976 169.514 1.00 86.24  ? 40  G   X C6    1 
ATOM   657  O  O6    . G   A 1 343 ? 157.788 163.357 170.237 1.00 86.24  ? 40  G   X O6    1 
ATOM   658  N  N1    . G   A 1 343 ? 158.385 163.987 168.150 1.00 86.24  ? 40  G   X N1    1 
ATOM   659  C  C2    . G   A 1 343 ? 159.188 164.633 167.261 1.00 86.24  ? 40  G   X C2    1 
ATOM   660  N  N2    . G   A 1 343 ? 158.842 164.525 165.979 1.00 86.24  ? 40  G   X N2    1 
ATOM   661  N  N3    . G   A 1 343 ? 160.250 165.330 167.588 1.00 86.24  ? 40  G   X N3    1 
ATOM   662  C  C4    . G   A 1 343 ? 160.445 165.330 168.909 1.00 86.24  ? 40  G   X C4    1 
ATOM   663  P  P     . A   A 1 344 ? 161.560 171.400 170.419 1.00 85.88  ? 41  A   X P     1 
ATOM   664  O  OP1   . A   A 1 344 ? 162.661 172.321 170.785 1.00 85.88  ? 41  A   X OP1   1 
ATOM   665  O  OP2   . A   A 1 344 ? 160.864 170.640 171.477 1.00 85.88  ? 41  A   X OP2   1 
ATOM   666  O  "O5'" . A   A 1 344 ? 160.459 172.213 169.611 1.00 85.88  ? 41  A   X "O5'" 1 
ATOM   667  C  "C5'" . A   A 1 344 ? 159.165 172.412 170.151 1.00 85.88  ? 41  A   X "C5'" 1 
ATOM   668  C  "C4'" . A   A 1 344 ? 158.101 171.871 169.236 1.00 85.88  ? 41  A   X "C4'" 1 
ATOM   669  O  "O4'" . A   A 1 344 ? 158.082 172.636 168.001 1.00 85.88  ? 41  A   X "O4'" 1 
ATOM   670  C  "C3'" . A   A 1 344 ? 158.306 170.449 168.761 1.00 85.88  ? 41  A   X "C3'" 1 
ATOM   671  O  "O3'" . A   A 1 344 ? 158.082 169.443 169.751 1.00 85.88  ? 41  A   X "O3'" 1 
ATOM   672  C  "C2'" . A   A 1 344 ? 157.464 170.416 167.495 1.00 85.88  ? 41  A   X "C2'" 1 
ATOM   673  O  "O2'" . A   A 1 344 ? 156.079 170.400 167.787 1.00 85.88  ? 41  A   X "O2'" 1 
ATOM   674  C  "C1'" . A   A 1 344 ? 157.793 171.782 166.913 1.00 85.88  ? 41  A   X "C1'" 1 
ATOM   675  N  N9    . A   A 1 344 ? 158.977 171.714 166.043 1.00 85.88  ? 41  A   X N9    1 
ATOM   676  C  C8    . A   A 1 344 ? 160.277 171.934 166.398 1.00 85.88  ? 41  A   X C8    1 
ATOM   677  N  N7    . A   A 1 344 ? 161.133 171.789 165.423 1.00 85.88  ? 41  A   X N7    1 
ATOM   678  C  C5    . A   A 1 344 ? 160.339 171.436 164.352 1.00 85.88  ? 41  A   X C5    1 
ATOM   679  C  C6    . A   A 1 344 ? 160.646 171.137 163.023 1.00 85.88  ? 41  A   X C6    1 
ATOM   680  N  N6    . A   A 1 344 ? 161.881 171.157 162.541 1.00 85.88  ? 41  A   X N6    1 
ATOM   681  N  N1    . A   A 1 344 ? 159.640 170.820 162.192 1.00 85.88  ? 41  A   X N1    1 
ATOM   682  C  C2    . A   A 1 344 ? 158.406 170.798 162.686 1.00 85.88  ? 41  A   X C2    1 
ATOM   683  N  N3    . A   A 1 344 ? 157.990 171.067 163.915 1.00 85.88  ? 41  A   X N3    1 
ATOM   684  C  C4    . A   A 1 344 ? 159.016 171.377 164.716 1.00 85.88  ? 41  A   X C4    1 
ATOM   685  P  P     . G   A 1 345 ? 156.735 168.573 169.869 1.00 86.21  ? 42  G   X P     1 
ATOM   686  O  OP1   . G   A 1 345 ? 155.561 169.473 169.892 1.00 86.21  ? 42  G   X OP1   1 
ATOM   687  O  OP2   . G   A 1 345 ? 156.931 167.613 170.973 1.00 86.21  ? 42  G   X OP2   1 
ATOM   688  O  "O5'" . G   A 1 345 ? 156.667 167.725 168.531 1.00 86.21  ? 42  G   X "O5'" 1 
ATOM   689  C  "C5'" . G   A 1 345 ? 155.448 167.115 168.150 1.00 86.21  ? 42  G   X "C5'" 1 
ATOM   690  C  "C4'" . G   A 1 345 ? 155.286 167.066 166.654 1.00 86.21  ? 42  G   X "C4'" 1 
ATOM   691  O  "O4'" . G   A 1 345 ? 156.087 168.096 166.037 1.00 86.21  ? 42  G   X "O4'" 1 
ATOM   692  C  "C3'" . G   A 1 345 ? 155.743 165.788 165.987 1.00 86.21  ? 42  G   X "C3'" 1 
ATOM   693  O  "O3'" . G   A 1 345 ? 154.743 164.794 166.033 1.00 86.21  ? 42  G   X "O3'" 1 
ATOM   694  C  "C2'" . G   A 1 345 ? 156.060 166.237 164.573 1.00 86.21  ? 42  G   X "C2'" 1 
ATOM   695  O  "O2'" . G   A 1 345 ? 154.866 166.344 163.825 1.00 86.21  ? 42  G   X "O2'" 1 
ATOM   696  C  "C1'" . G   A 1 345 ? 156.587 167.645 164.803 1.00 86.21  ? 42  G   X "C1'" 1 
ATOM   697  N  N9    . G   A 1 345 ? 158.051 167.716 164.855 1.00 86.21  ? 42  G   X N9    1 
ATOM   698  C  C8    . G   A 1 345 ? 158.774 167.879 165.992 1.00 86.21  ? 42  G   X C8    1 
ATOM   699  N  N7    . G   A 1 345 ? 160.046 167.943 165.787 1.00 86.21  ? 42  G   X N7    1 
ATOM   700  C  C5    . G   A 1 345 ? 160.165 167.810 164.426 1.00 86.21  ? 42  G   X C5    1 
ATOM   701  C  C6    . G   A 1 345 ? 161.317 167.798 163.633 1.00 86.21  ? 42  G   X C6    1 
ATOM   702  O  O6    . G   A 1 345 ? 162.485 167.900 163.998 1.00 86.21  ? 42  G   X O6    1 
ATOM   703  N  N1    . G   A 1 345 ? 161.018 167.638 162.296 1.00 86.21  ? 42  G   X N1    1 
ATOM   704  C  C2    . G   A 1 345 ? 159.761 167.511 161.797 1.00 86.21  ? 42  G   X C2    1 
ATOM   705  N  N2    . G   A 1 345 ? 159.676 167.365 160.472 1.00 86.21  ? 42  G   X N2    1 
ATOM   706  N  N3    . G   A 1 345 ? 158.670 167.521 162.530 1.00 86.21  ? 42  G   X N3    1 
ATOM   707  C  C4    . G   A 1 345 ? 158.947 167.673 163.829 1.00 86.21  ? 42  G   X C4    1 
ATOM   708  P  P     . A   A 1 346 ? 154.900 163.538 167.007 1.00 88.49  ? 43  A   X P     1 
ATOM   709  O  OP1   . A   A 1 346 ? 153.611 162.822 167.066 1.00 88.49  ? 43  A   X OP1   1 
ATOM   710  O  OP2   . A   A 1 346 ? 155.545 163.987 168.255 1.00 88.49  ? 43  A   X OP2   1 
ATOM   711  O  "O5'" . A   A 1 346 ? 155.934 162.616 166.242 1.00 88.49  ? 43  A   X "O5'" 1 
ATOM   712  C  "C5'" . A   A 1 346 ? 155.918 162.539 164.828 1.00 88.49  ? 43  A   X "C5'" 1 
ATOM   713  C  "C4'" . A   A 1 346 ? 156.579 161.280 164.363 1.00 88.49  ? 43  A   X "C4'" 1 
ATOM   714  O  "O4'" . A   A 1 346 ? 158.000 161.517 164.183 1.00 88.49  ? 43  A   X "O4'" 1 
ATOM   715  C  "C3'" . A   A 1 346 ? 156.458 160.119 165.342 1.00 88.49  ? 43  A   X "C3'" 1 
ATOM   716  O  "O3'" . A   A 1 346 ? 156.219 158.914 164.633 1.00 88.49  ? 43  A   X "O3'" 1 
ATOM   717  C  "C2'" . A   A 1 346 ? 157.832 160.073 165.996 1.00 88.49  ? 43  A   X "C2'" 1 
ATOM   718  O  "O2'" . A   A 1 346 ? 158.210 158.808 166.489 1.00 88.49  ? 43  A   X "O2'" 1 
ATOM   719  C  "C1'" . A   A 1 346 ? 158.723 160.516 164.855 1.00 88.49  ? 43  A   X "C1'" 1 
ATOM   720  N  N9    . A   A 1 346 ? 160.008 161.042 165.299 1.00 88.49  ? 43  A   X N9    1 
ATOM   721  C  C8    . A   A 1 346 ? 160.318 161.386 166.580 1.00 88.49  ? 43  A   X C8    1 
ATOM   722  N  N7    . A   A 1 346 ? 161.544 161.796 166.728 1.00 88.49  ? 43  A   X N7    1 
ATOM   723  C  C5    . A   A 1 346 ? 162.076 161.704 165.459 1.00 88.49  ? 43  A   X C5    1 
ATOM   724  C  C6    . A   A 1 346 ? 163.345 161.998 164.967 1.00 88.49  ? 43  A   X C6    1 
ATOM   725  N  N6    . A   A 1 346 ? 164.327 162.463 165.730 1.00 88.49  ? 43  A   X N6    1 
ATOM   726  N  N1    . A   A 1 346 ? 163.568 161.802 163.658 1.00 88.49  ? 43  A   X N1    1 
ATOM   727  C  C2    . A   A 1 346 ? 162.563 161.345 162.914 1.00 88.49  ? 43  A   X C2    1 
ATOM   728  N  N3    . A   A 1 346 ? 161.328 161.024 163.264 1.00 88.49  ? 43  A   X N3    1 
ATOM   729  C  C4    . A   A 1 346 ? 161.146 161.232 164.567 1.00 88.49  ? 43  A   X C4    1 
ATOM   730  P  P     . A   A 1 347 ? 154.943 158.026 165.021 1.00 92.73  ? 44  A   X P     1 
ATOM   731  O  OP1   . A   A 1 347 ? 154.581 158.343 166.418 1.00 92.73  ? 44  A   X OP1   1 
ATOM   732  O  OP2   . A   A 1 347 ? 155.208 156.626 164.629 1.00 92.73  ? 44  A   X OP2   1 
ATOM   733  O  "O5'" . A   A 1 347 ? 153.782 158.611 164.112 1.00 92.73  ? 44  A   X "O5'" 1 
ATOM   734  C  "C5'" . A   A 1 347 ? 153.073 159.779 164.501 1.00 92.73  ? 44  A   X "C5'" 1 
ATOM   735  C  "C4'" . A   A 1 347 ? 151.930 160.067 163.565 1.00 92.73  ? 44  A   X "C4'" 1 
ATOM   736  O  "O4'" . A   A 1 347 ? 152.451 160.446 162.260 1.00 92.73  ? 44  A   X "O4'" 1 
ATOM   737  C  "C3'" . A   A 1 347 ? 150.994 158.887 163.320 1.00 92.73  ? 44  A   X "C3'" 1 
ATOM   738  O  "O3'" . A   A 1 347 ? 149.668 159.371 163.138 1.00 92.73  ? 44  A   X "O3'" 1 
ATOM   739  C  "C2'" . A   A 1 347 ? 151.509 158.330 162.003 1.00 92.73  ? 44  A   X "C2'" 1 
ATOM   740  O  "O2'" . A   A 1 347 ? 150.575 157.566 161.276 1.00 92.73  ? 44  A   X "O2'" 1 
ATOM   741  C  "C1'" . A   A 1 347 ? 151.884 159.610 161.275 1.00 92.73  ? 44  A   X "C1'" 1 
ATOM   742  N  N9    . A   A 1 347 ? 152.837 159.414 160.184 1.00 92.73  ? 44  A   X N9    1 
ATOM   743  C  C8    . A   A 1 347 ? 154.145 159.017 160.231 1.00 92.73  ? 44  A   X C8    1 
ATOM   744  N  N7    . A   A 1 347 ? 154.706 158.927 159.049 1.00 92.73  ? 44  A   X N7    1 
ATOM   745  C  C5    . A   A 1 347 ? 153.697 159.280 158.177 1.00 92.73  ? 44  A   X C5    1 
ATOM   746  C  C6    . A   A 1 347 ? 153.655 159.379 156.784 1.00 92.73  ? 44  A   X C6    1 
ATOM   747  N  N6    . A   A 1 347 ? 154.701 159.121 155.999 1.00 92.73  ? 44  A   X N6    1 
ATOM   748  N  N1    . A   A 1 347 ? 152.493 159.760 156.220 1.00 92.73  ? 44  A   X N1    1 
ATOM   749  C  C2    . A   A 1 347 ? 151.456 160.015 157.023 1.00 92.73  ? 44  A   X C2    1 
ATOM   750  N  N3    . A   A 1 347 ? 151.377 159.957 158.346 1.00 92.73  ? 44  A   X N3    1 
ATOM   751  C  C4    . A   A 1 347 ? 152.545 159.581 158.863 1.00 92.73  ? 44  A   X C4    1 
ATOM   752  P  P     . A   A 1 348 ? 148.544 159.056 164.236 1.00 97.95  ? 45  A   X P     1 
ATOM   753  O  OP1   . A   A 1 348 ? 149.196 158.384 165.383 1.00 97.95  ? 45  A   X OP1   1 
ATOM   754  O  OP2   . A   A 1 348 ? 147.397 158.414 163.553 1.00 97.95  ? 45  A   X OP2   1 
ATOM   755  O  "O5'" . A   A 1 348 ? 148.075 160.492 164.726 1.00 97.95  ? 45  A   X "O5'" 1 
ATOM   756  C  "C5'" . A   A 1 348 ? 147.228 161.295 163.922 1.00 97.95  ? 45  A   X "C5'" 1 
ATOM   757  C  "C4'" . A   A 1 348 ? 147.502 162.757 164.143 1.00 97.95  ? 45  A   X "C4'" 1 
ATOM   758  O  "O4'" . A   A 1 348 ? 148.862 163.059 163.739 1.00 97.95  ? 45  A   X "O4'" 1 
ATOM   759  C  "C3'" . A   A 1 348 ? 146.659 163.731 163.339 1.00 97.95  ? 45  A   X "C3'" 1 
ATOM   760  O  "O3'" . A   A 1 348 ? 145.377 163.960 163.899 1.00 97.95  ? 45  A   X "O3'" 1 
ATOM   761  C  "C2'" . A   A 1 348 ? 147.534 164.970 163.326 1.00 97.95  ? 45  A   X "C2'" 1 
ATOM   762  O  "O2'" . A   A 1 348 ? 147.476 165.615 164.587 1.00 97.95  ? 45  A   X "O2'" 1 
ATOM   763  C  "C1'" . A   A 1 348 ? 148.922 164.354 163.186 1.00 97.95  ? 45  A   X "C1'" 1 
ATOM   764  N  N9    . A   A 1 348 ? 149.332 164.234 161.778 1.00 97.95  ? 45  A   X N9    1 
ATOM   765  C  C8    . A   A 1 348 ? 148.546 164.368 160.673 1.00 97.95  ? 45  A   X C8    1 
ATOM   766  N  N7    . A   A 1 348 ? 149.184 164.196 159.550 1.00 97.95  ? 45  A   X N7    1 
ATOM   767  C  C5    . A   A 1 348 ? 150.479 163.926 159.941 1.00 97.95  ? 45  A   X C5    1 
ATOM   768  C  C6    . A   A 1 348 ? 151.638 163.656 159.207 1.00 97.95  ? 45  A   X C6    1 
ATOM   769  N  N6    . A   A 1 348 ? 151.687 163.607 157.878 1.00 97.95  ? 45  A   X N6    1 
ATOM   770  N  N1    . A   A 1 348 ? 152.767 163.438 159.890 1.00 97.95  ? 45  A   X N1    1 
ATOM   771  C  C2    . A   A 1 348 ? 152.725 163.488 161.222 1.00 97.95  ? 45  A   X C2    1 
ATOM   772  N  N3    . A   A 1 348 ? 151.696 163.734 162.024 1.00 97.95  ? 45  A   X N3    1 
ATOM   773  C  C4    . A   A 1 348 ? 150.588 163.951 161.310 1.00 97.95  ? 45  A   X C4    1 
ATOM   774  P  P     . U   A 1 349 ? 144.055 163.405 163.172 1.00 105.12 ? 46  U   X P     1 
ATOM   775  O  OP1   . U   A 1 349 ? 142.885 163.747 164.015 1.00 105.12 ? 46  U   X OP1   1 
ATOM   776  O  OP2   . U   A 1 349 ? 144.313 162.000 162.778 1.00 105.12 ? 46  U   X OP2   1 
ATOM   777  O  "O5'" . U   A 1 349 ? 143.934 164.258 161.834 1.00 105.12 ? 46  U   X "O5'" 1 
ATOM   778  C  "C5'" . U   A 1 349 ? 143.608 165.642 161.865 1.00 105.12 ? 46  U   X "C5'" 1 
ATOM   779  C  "C4'" . U   A 1 349 ? 144.737 166.457 161.301 1.00 105.12 ? 46  U   X "C4'" 1 
ATOM   780  O  "O4'" . U   A 1 349 ? 145.622 165.565 160.578 1.00 105.12 ? 46  U   X "O4'" 1 
ATOM   781  C  "C3'" . U   A 1 349 ? 144.346 167.551 160.310 1.00 105.12 ? 46  U   X "C3'" 1 
ATOM   782  O  "O3'" . U   A 1 349 ? 145.324 168.590 160.384 1.00 105.12 ? 46  U   X "O3'" 1 
ATOM   783  C  "C2'" . U   A 1 349 ? 144.504 166.836 158.976 1.00 105.12 ? 46  U   X "C2'" 1 
ATOM   784  O  "O2'" . U   A 1 349 ? 144.681 167.691 157.870 1.00 105.12 ? 46  U   X "O2'" 1 
ATOM   785  C  "C1'" . U   A 1 349 ? 145.751 166.012 159.249 1.00 105.12 ? 46  U   X "C1'" 1 
ATOM   786  N  N1    . U   A 1 349 ? 145.949 164.848 158.383 1.00 105.12 ? 46  U   X N1    1 
ATOM   787  C  C2    . U   A 1 349 ? 146.934 164.986 157.439 1.00 105.12 ? 46  U   X C2    1 
ATOM   788  O  O2    . U   A 1 349 ? 147.565 166.021 157.324 1.00 105.12 ? 46  U   X O2    1 
ATOM   789  N  N3    . U   A 1 349 ? 147.142 163.887 156.643 1.00 105.12 ? 46  U   X N3    1 
ATOM   790  C  C4    . U   A 1 349 ? 146.469 162.686 156.712 1.00 105.12 ? 46  U   X C4    1 
ATOM   791  O  O4    . U   A 1 349 ? 146.762 161.786 155.927 1.00 105.12 ? 46  U   X O4    1 
ATOM   792  C  C5    . U   A 1 349 ? 145.469 162.621 157.732 1.00 105.12 ? 46  U   X C5    1 
ATOM   793  C  C6    . U   A 1 349 ? 145.249 163.679 158.521 1.00 105.12 ? 46  U   X C6    1 
ATOM   794  P  P     . A   A 1 350 ? 144.928 170.107 160.735 1.00 96.72  ? 47  A   X P     1 
ATOM   795  O  OP1   . A   A 1 350 ? 143.591 170.131 161.372 1.00 96.72  ? 47  A   X OP1   1 
ATOM   796  O  OP2   . A   A 1 350 ? 145.207 170.947 159.547 1.00 96.72  ? 47  A   X OP2   1 
ATOM   797  O  "O5'" . A   A 1 350 ? 145.991 170.528 161.835 1.00 96.72  ? 47  A   X "O5'" 1 
ATOM   798  C  "C5'" . A   A 1 350 ? 145.731 170.310 163.210 1.00 96.72  ? 47  A   X "C5'" 1 
ATOM   799  C  "C4'" . A   A 1 350 ? 146.936 169.746 163.912 1.00 96.72  ? 47  A   X "C4'" 1 
ATOM   800  O  "O4'" . A   A 1 350 ? 147.259 168.452 163.361 1.00 96.72  ? 47  A   X "O4'" 1 
ATOM   801  C  "C3'" . A   A 1 350 ? 148.222 170.540 163.772 1.00 96.72  ? 47  A   X "C3'" 1 
ATOM   802  O  "O3'" . A   A 1 350 ? 148.285 171.606 164.702 1.00 96.72  ? 47  A   X "O3'" 1 
ATOM   803  C  "C2'" . A   A 1 350 ? 149.294 169.489 164.008 1.00 96.72  ? 47  A   X "C2'" 1 
ATOM   804  O  "O2'" . A   A 1 350 ? 149.479 169.286 165.397 1.00 96.72  ? 47  A   X "O2'" 1 
ATOM   805  C  "C1'" . A   A 1 350 ? 148.646 168.236 163.428 1.00 96.72  ? 47  A   X "C1'" 1 
ATOM   806  N  N9    . A   A 1 350 ? 149.141 167.893 162.086 1.00 96.72  ? 47  A   X N9    1 
ATOM   807  C  C8    . A   A 1 350 ? 148.431 167.862 160.923 1.00 96.72  ? 47  A   X C8    1 
ATOM   808  N  N7    . A   A 1 350 ? 149.132 167.500 159.882 1.00 96.72  ? 47  A   X N7    1 
ATOM   809  C  C5    . A   A 1 350 ? 150.382 167.266 160.405 1.00 96.72  ? 47  A   X C5    1 
ATOM   810  C  C6    . A   A 1 350 ? 151.568 166.866 159.806 1.00 96.72  ? 47  A   X C6    1 
ATOM   811  N  N6    . A   A 1 350 ? 151.657 166.619 158.508 1.00 96.72  ? 47  A   X N6    1 
ATOM   812  N  N1    . A   A 1 350 ? 152.649 166.722 160.582 1.00 96.72  ? 47  A   X N1    1 
ATOM   813  C  C2    . A   A 1 350 ? 152.521 166.981 161.880 1.00 96.72  ? 47  A   X C2    1 
ATOM   814  N  N3    . A   A 1 350 ? 151.456 167.371 162.565 1.00 96.72  ? 47  A   X N3    1 
ATOM   815  C  C4    . A   A 1 350 ? 150.405 167.495 161.755 1.00 96.72  ? 47  A   X C4    1 
ATOM   816  P  P     . C   A 1 351 ? 149.206 172.891 164.430 1.00 91.17  ? 48  C   X P     1 
ATOM   817  O  OP1   . C   A 1 351 ? 149.237 173.685 165.677 1.00 91.17  ? 48  C   X OP1   1 
ATOM   818  O  OP2   . C   A 1 351 ? 148.782 173.529 163.165 1.00 91.17  ? 48  C   X OP2   1 
ATOM   819  O  "O5'" . C   A 1 351 ? 150.661 172.295 164.221 1.00 91.17  ? 48  C   X "O5'" 1 
ATOM   820  C  "C5'" . C   A 1 351 ? 151.462 171.932 165.329 1.00 91.17  ? 48  C   X "C5'" 1 
ATOM   821  C  "C4'" . C   A 1 351 ? 152.820 171.474 164.880 1.00 91.17  ? 48  C   X "C4'" 1 
ATOM   822  O  "O4'" . C   A 1 351 ? 152.685 170.308 164.039 1.00 91.17  ? 48  C   X "O4'" 1 
ATOM   823  C  "C3'" . C   A 1 351 ? 153.580 172.457 164.019 1.00 91.17  ? 48  C   X "C3'" 1 
ATOM   824  O  "O3'" . C   A 1 351 ? 154.235 173.437 164.792 1.00 91.17  ? 48  C   X "O3'" 1 
ATOM   825  C  "C2'" . C   A 1 351 ? 154.534 171.561 163.254 1.00 91.17  ? 48  C   X "C2'" 1 
ATOM   826  O  "O2'" . C   A 1 351 ? 155.633 171.214 164.075 1.00 91.17  ? 48  C   X "O2'" 1 
ATOM   827  C  "C1'" . C   A 1 351 ? 153.686 170.310 163.052 1.00 91.17  ? 48  C   X "C1'" 1 
ATOM   828  N  N1    . C   A 1 351 ? 153.037 170.238 161.725 1.00 91.17  ? 48  C   X N1    1 
ATOM   829  C  C2    . C   A 1 351 ? 153.772 169.824 160.621 1.00 91.17  ? 48  C   X C2    1 
ATOM   830  O  O2    . C   A 1 351 ? 154.965 169.559 160.778 1.00 91.17  ? 48  C   X O2    1 
ATOM   831  N  N3    . C   A 1 351 ? 153.183 169.732 159.414 1.00 91.17  ? 48  C   X N3    1 
ATOM   832  C  C4    . C   A 1 351 ? 151.897 170.027 159.293 1.00 91.17  ? 48  C   X C4    1 
ATOM   833  N  N4    . C   A 1 351 ? 151.343 169.921 158.087 1.00 91.17  ? 48  C   X N4    1 
ATOM   834  C  C5    . C   A 1 351 ? 151.115 170.436 160.404 1.00 91.17  ? 48  C   X C5    1 
ATOM   835  C  C6    . C   A 1 351 ? 151.718 170.520 161.591 1.00 91.17  ? 48  C   X C6    1 
ATOM   836  P  P     . C   A 1 352 ? 154.260 174.960 164.309 1.00 84.89  ? 49  C   X P     1 
ATOM   837  O  OP1   . C   A 1 352 ? 154.755 175.760 165.446 1.00 84.89  ? 49  C   X OP1   1 
ATOM   838  O  OP2   . C   A 1 352 ? 152.967 175.281 163.673 1.00 84.89  ? 49  C   X OP2   1 
ATOM   839  O  "O5'" . C   A 1 352 ? 155.393 174.979 163.202 1.00 84.89  ? 49  C   X "O5'" 1 
ATOM   840  C  "C5'" . C   A 1 352 ? 156.736 174.750 163.573 1.00 84.89  ? 49  C   X "C5'" 1 
ATOM   841  C  "C4'" . C   A 1 352 ? 157.583 174.343 162.402 1.00 84.89  ? 49  C   X "C4'" 1 
ATOM   842  O  "O4'" . C   A 1 352 ? 157.032 173.166 161.777 1.00 84.89  ? 49  C   X "O4'" 1 
ATOM   843  C  "C3'" . C   A 1 352 ? 157.675 175.335 161.268 1.00 84.89  ? 49  C   X "C3'" 1 
ATOM   844  O  "O3'" . C   A 1 352 ? 158.577 176.385 161.540 1.00 84.89  ? 49  C   X "O3'" 1 
ATOM   845  C  "C2'" . C   A 1 352 ? 158.104 174.454 160.112 1.00 84.89  ? 49  C   X "C2'" 1 
ATOM   846  O  "O2'" . C   A 1 352 ? 159.479 174.151 160.222 1.00 84.89  ? 49  C   X "O2'" 1 
ATOM   847  C  "C1'" . C   A 1 352 ? 157.325 173.181 160.401 1.00 84.89  ? 49  C   X "C1'" 1 
ATOM   848  N  N1    . C   A 1 352 ? 156.057 173.106 159.652 1.00 84.89  ? 49  C   X N1    1 
ATOM   849  C  C2    . C   A 1 352 ? 156.070 172.718 158.326 1.00 84.89  ? 49  C   X C2    1 
ATOM   850  O  O2    . C   A 1 352 ? 157.150 172.458 157.796 1.00 84.89  ? 49  C   X O2    1 
ATOM   851  N  N3    . C   A 1 352 ? 154.913 172.636 157.646 1.00 84.89  ? 49  C   X N3    1 
ATOM   852  C  C4    . C   A 1 352 ? 153.772 172.922 158.253 1.00 84.89  ? 49  C   X C4    1 
ATOM   853  N  N4    . C   A 1 352 ? 152.644 172.831 157.553 1.00 84.89  ? 49  C   X N4    1 
ATOM   854  C  C5    . C   A 1 352 ? 153.726 173.316 159.610 1.00 84.89  ? 49  C   X C5    1 
ATOM   855  C  C6    . C   A 1 352 ? 154.883 173.391 160.261 1.00 84.89  ? 49  C   X C6    1 
ATOM   856  P  P     . C   A 1 353 ? 158.315 177.845 160.939 1.00 84.00  ? 50  C   X P     1 
ATOM   857  O  OP1   . C   A 1 353 ? 159.357 178.730 161.504 1.00 84.00  ? 50  C   X OP1   1 
ATOM   858  O  OP2   . C   A 1 353 ? 156.886 178.189 161.088 1.00 84.00  ? 50  C   X OP2   1 
ATOM   859  O  "O5'" . C   A 1 353 ? 158.599 177.673 159.387 1.00 84.00  ? 50  C   X "O5'" 1 
ATOM   860  C  "C5'" . C   A 1 353 ? 159.880 177.283 158.926 1.00 84.00  ? 50  C   X "C5'" 1 
ATOM   861  C  "C4'" . C   A 1 353 ? 159.834 176.846 157.488 1.00 84.00  ? 50  C   X "C4'" 1 
ATOM   862  O  "O4'" . C   A 1 353 ? 158.891 175.762 157.334 1.00 84.00  ? 50  C   X "O4'" 1 
ATOM   863  C  "C3'" . C   A 1 353 ? 159.351 177.886 156.504 1.00 84.00  ? 50  C   X "C3'" 1 
ATOM   864  O  "O3'" . C   A 1 353 ? 160.365 178.801 156.151 1.00 84.00  ? 50  C   X "O3'" 1 
ATOM   865  C  "C2'" . C   A 1 353 ? 158.872 177.039 155.343 1.00 84.00  ? 50  C   X "C2'" 1 
ATOM   866  O  "O2'" . C   A 1 353 ? 159.971 176.588 154.576 1.00 84.00  ? 50  C   X "O2'" 1 
ATOM   867  C  "C1'" . C   A 1 353 ? 158.282 175.838 156.069 1.00 84.00  ? 50  C   X "C1'" 1 
ATOM   868  N  N1    . C   A 1 353 ? 156.820 175.944 156.241 1.00 84.00  ? 50  C   X N1    1 
ATOM   869  C  C2    . C   A 1 353 ? 156.036 175.631 155.150 1.00 84.00  ? 50  C   X C2    1 
ATOM   870  O  O2    . C   A 1 353 ? 156.608 175.292 154.117 1.00 84.00  ? 50  C   X O2    1 
ATOM   871  N  N3    . C   A 1 353 ? 154.699 175.698 155.227 1.00 84.00  ? 50  C   X N3    1 
ATOM   872  C  C4    . C   A 1 353 ? 154.136 176.062 156.366 1.00 84.00  ? 50  C   X C4    1 
ATOM   873  N  N4    . C   A 1 353 ? 152.808 176.115 156.402 1.00 84.00  ? 50  C   X N4    1 
ATOM   874  C  C5    . C   A 1 353 ? 154.906 176.392 157.510 1.00 84.00  ? 50  C   X C5    1 
ATOM   875  C  C6    . C   A 1 353 ? 156.236 176.318 157.405 1.00 84.00  ? 50  C   X C6    1 
ATOM   876  P  P     . G   A 1 354 ? 159.984 180.272 155.657 1.00 86.54  ? 51  G   X P     1 
ATOM   877  O  OP1   . G   A 1 354 ? 161.254 181.019 155.540 1.00 86.54  ? 51  G   X OP1   1 
ATOM   878  O  OP2   . G   A 1 354 ? 158.882 180.804 156.489 1.00 86.54  ? 51  G   X OP2   1 
ATOM   879  O  "O5'" . G   A 1 354 ? 159.413 180.042 154.194 1.00 86.54  ? 51  G   X "O5'" 1 
ATOM   880  C  "C5'" . G   A 1 354 ? 160.276 179.709 153.123 1.00 86.54  ? 51  G   X "C5'" 1 
ATOM   881  C  "C4'" . G   A 1 354 ? 159.500 179.394 151.876 1.00 86.54  ? 51  G   X "C4'" 1 
ATOM   882  O  "O4'" . G   A 1 354 ? 158.529 178.367 152.159 1.00 86.54  ? 51  G   X "O4'" 1 
ATOM   883  C  "C3'" . G   A 1 354 ? 158.667 180.520 151.307 1.00 86.54  ? 51  G   X "C3'" 1 
ATOM   884  O  "O3'" . G   A 1 354 ? 159.424 181.414 150.532 1.00 86.54  ? 51  G   X "O3'" 1 
ATOM   885  C  "C2'" . G   A 1 354 ? 157.636 179.779 150.483 1.00 86.54  ? 51  G   X "C2'" 1 
ATOM   886  O  "O2'" . G   A 1 354 ? 158.201 179.369 149.254 1.00 86.54  ? 51  G   X "O2'" 1 
ATOM   887  C  "C1'" . G   A 1 354 ? 157.406 178.537 151.327 1.00 86.54  ? 51  G   X "C1'" 1 
ATOM   888  N  N9    . G   A 1 354 ? 156.191 178.642 152.144 1.00 86.54  ? 51  G   X N9    1 
ATOM   889  C  C8    . G   A 1 354 ? 156.070 178.804 153.493 1.00 86.54  ? 51  G   X C8    1 
ATOM   890  N  N7    . G   A 1 354 ? 154.828 178.847 153.875 1.00 86.54  ? 51  G   X N7    1 
ATOM   891  C  C5    . G   A 1 354 ? 154.100 178.704 152.709 1.00 86.54  ? 51  G   X C5    1 
ATOM   892  C  C6    . G   A 1 354 ? 152.710 178.676 152.481 1.00 86.54  ? 51  G   X C6    1 
ATOM   893  O  O6    . G   A 1 354 ? 151.791 178.772 153.292 1.00 86.54  ? 51  G   X O6    1 
ATOM   894  N  N1    . G   A 1 354 ? 152.408 178.513 151.141 1.00 86.54  ? 51  G   X N1    1 
ATOM   895  C  C2    . G   A 1 354 ? 153.327 178.392 150.143 1.00 86.54  ? 51  G   X C2    1 
ATOM   896  N  N2    . G   A 1 354 ? 152.855 178.244 148.903 1.00 86.54  ? 51  G   X N2    1 
ATOM   897  N  N3    . G   A 1 354 ? 154.622 178.419 150.339 1.00 86.54  ? 51  G   X N3    1 
ATOM   898  C  C4    . G   A 1 354 ? 154.930 178.573 151.636 1.00 86.54  ? 51  G   X C4    1 
ATOM   899  P  P     . U   A 1 355 ? 159.853 182.827 151.135 1.00 91.13  ? 52  U   X P     1 
ATOM   900  O  OP1   . U   A 1 355 ? 159.038 183.098 152.341 1.00 91.13  ? 52  U   X OP1   1 
ATOM   901  O  OP2   . U   A 1 355 ? 159.828 183.790 150.017 1.00 91.13  ? 52  U   X OP2   1 
ATOM   902  O  "O5'" . U   A 1 355 ? 161.362 182.588 151.571 1.00 91.13  ? 52  U   X "O5'" 1 
ATOM   903  C  "C5'" . U   A 1 355 ? 162.222 183.679 151.856 1.00 91.13  ? 52  U   X "C5'" 1 
ATOM   904  C  "C4'" . U   A 1 355 ? 163.296 183.834 150.809 1.00 91.13  ? 52  U   X "C4'" 1 
ATOM   905  O  "O4'" . U   A 1 355 ? 163.419 182.606 150.034 1.00 91.13  ? 52  U   X "O4'" 1 
ATOM   906  C  "C3'" . U   A 1 355 ? 163.063 184.961 149.799 1.00 91.13  ? 52  U   X "C3'" 1 
ATOM   907  O  "O3'" . U   A 1 355 ? 164.271 185.649 149.459 1.00 91.13  ? 52  U   X "O3'" 1 
ATOM   908  C  "C2'" . U   A 1 355 ? 162.566 184.213 148.570 1.00 91.13  ? 52  U   X "C2'" 1 
ATOM   909  O  "O2'" . U   A 1 355 ? 162.794 184.876 147.346 1.00 91.13  ? 52  U   X "O2'" 1 
ATOM   910  C  "C1'" . U   A 1 355 ? 163.350 182.911 148.658 1.00 91.13  ? 52  U   X "C1'" 1 
ATOM   911  N  N1    . U   A 1 355 ? 162.683 181.821 147.938 1.00 91.13  ? 52  U   X N1    1 
ATOM   912  C  C2    . U   A 1 355 ? 162.905 181.780 146.587 1.00 91.13  ? 52  U   X C2    1 
ATOM   913  O  O2    . U   A 1 355 ? 163.636 182.568 146.024 1.00 91.13  ? 52  U   X O2    1 
ATOM   914  N  N3    . U   A 1 355 ? 162.253 180.792 145.911 1.00 91.13  ? 52  U   X N3    1 
ATOM   915  C  C4    . U   A 1 355 ? 161.406 179.862 146.445 1.00 91.13  ? 52  U   X C4    1 
ATOM   916  O  O4    . U   A 1 355 ? 160.895 179.031 145.707 1.00 91.13  ? 52  U   X O4    1 
ATOM   917  C  C5    . U   A 1 355 ? 161.212 179.973 147.849 1.00 91.13  ? 52  U   X C5    1 
ATOM   918  C  C6    . U   A 1 355 ? 161.836 180.933 148.532 1.00 91.13  ? 52  U   X C6    1 
ATOM   919  P  P     . A   A 1 356 ? 165.595 185.562 150.357 1.00 92.65  ? 53  A   X P     1 
ATOM   920  O  OP1   . A   A 1 356 ? 165.288 185.816 151.784 1.00 92.65  ? 53  A   X OP1   1 
ATOM   921  O  OP2   . A   A 1 356 ? 166.598 186.425 149.701 1.00 92.65  ? 53  A   X OP2   1 
ATOM   922  O  "O5'" . A   A 1 356 ? 166.075 184.065 150.153 1.00 92.65  ? 53  A   X "O5'" 1 
ATOM   923  C  "C5'" . A   A 1 356 ? 167.424 183.696 150.348 1.00 92.65  ? 53  A   X "C5'" 1 
ATOM   924  C  "C4'" . A   A 1 356 ? 167.583 182.860 151.584 1.00 92.65  ? 53  A   X "C4'" 1 
ATOM   925  O  "O4'" . A   A 1 356 ? 166.442 181.975 151.723 1.00 92.65  ? 53  A   X "O4'" 1 
ATOM   926  C  "C3'" . A   A 1 356 ? 168.822 181.976 151.593 1.00 92.65  ? 53  A   X "C3'" 1 
ATOM   927  O  "O3'" . A   A 1 356 ? 169.386 181.968 152.898 1.00 92.65  ? 53  A   X "O3'" 1 
ATOM   928  C  "C2'" . A   A 1 356 ? 168.270 180.599 151.240 1.00 92.65  ? 53  A   X "C2'" 1 
ATOM   929  O  "O2'" . A   A 1 356 ? 169.025 179.516 151.734 1.00 92.65  ? 53  A   X "O2'" 1 
ATOM   930  C  "C1'" . A   A 1 356 ? 166.887 180.646 151.870 1.00 92.65  ? 53  A   X "C1'" 1 
ATOM   931  N  N9    . A   A 1 356 ? 165.909 179.766 151.237 1.00 20.00  ? 53  A   X N9    1 
ATOM   932  C  C8    . A   A 1 356 ? 165.025 178.962 151.897 1.00 20.00  ? 53  A   X C8    1 
ATOM   933  N  N7    . A   A 1 356 ? 164.255 178.266 151.101 1.00 20.00  ? 53  A   X N7    1 
ATOM   934  C  C5    . A   A 1 356 ? 164.657 178.640 149.833 1.00 20.00  ? 53  A   X C5    1 
ATOM   935  C  C6    . A   A 1 356 ? 164.219 178.258 148.561 1.00 20.00  ? 53  A   X C6    1 
ATOM   936  N  N6    . A   A 1 356 ? 163.237 177.372 148.363 1.00 20.00  ? 53  A   X N6    1 
ATOM   937  N  N1    . A   A 1 356 ? 164.821 178.816 147.490 1.00 20.00  ? 53  A   X N1    1 
ATOM   938  C  C2    . A   A 1 356 ? 165.803 179.701 147.701 1.00 20.00  ? 53  A   X C2    1 
ATOM   939  N  N3    . A   A 1 356 ? 166.308 180.142 148.854 1.00 20.00  ? 53  A   X N3    1 
ATOM   940  C  C4    . A   A 1 356 ? 165.685 179.569 149.895 1.00 20.00  ? 53  A   X C4    1 
ATOM   941  P  P     . U   A 1 357 ? 170.330 183.185 153.347 1.00 101.85 ? 54  U   X P     1 
ATOM   942  O  OP1   . U   A 1 357 ? 170.047 183.510 154.766 1.00 101.85 ? 54  U   X OP1   1 
ATOM   943  O  OP2   . U   A 1 357 ? 170.232 184.248 152.323 1.00 101.85 ? 54  U   X OP2   1 
ATOM   944  O  "O5'" . U   A 1 357 ? 171.796 182.583 153.253 1.00 101.85 ? 54  U   X "O5'" 1 
ATOM   945  C  "C5'" . U   A 1 357 ? 172.016 181.309 152.670 1.00 101.85 ? 54  U   X "C5'" 1 
ATOM   946  C  "C4'" . U   A 1 357 ? 172.358 180.283 153.718 1.00 101.85 ? 54  U   X "C4'" 1 
ATOM   947  O  "O4'" . U   A 1 357 ? 173.568 180.700 154.404 1.00 101.85 ? 54  U   X "O4'" 1 
ATOM   948  C  "C3'" . U   A 1 357 ? 171.305 180.081 154.801 1.00 101.85 ? 54  U   X "C3'" 1 
ATOM   949  O  "O3'" . U   A 1 357 ? 171.325 178.722 155.226 1.00 101.85 ? 54  U   X "O3'" 1 
ATOM   950  C  "C2'" . U   A 1 357 ? 171.810 180.971 155.929 1.00 101.85 ? 54  U   X "C2'" 1 
ATOM   951  O  "O2'" . U   A 1 357 ? 171.359 180.595 157.211 1.00 101.85 ? 54  U   X "O2'" 1 
ATOM   952  C  "C1'" . U   A 1 357 ? 173.318 180.810 155.789 1.00 101.85 ? 54  U   X "C1'" 1 
ATOM   953  N  N1    . U   A 1 357 ? 174.088 181.953 156.283 1.00 101.85 ? 54  U   X N1    1 
ATOM   954  C  C2    . U   A 1 357 ? 174.986 181.717 157.293 1.00 101.85 ? 54  U   X C2    1 
ATOM   955  O  O2    . U   A 1 357 ? 175.149 180.617 157.784 1.00 101.85 ? 54  U   X O2    1 
ATOM   956  N  N3    . U   A 1 357 ? 175.682 182.816 157.711 1.00 101.85 ? 54  U   X N3    1 
ATOM   957  C  C4    . U   A 1 357 ? 175.573 184.097 157.222 1.00 101.85 ? 54  U   X C4    1 
ATOM   958  O  O4    . U   A 1 357 ? 176.275 184.984 157.706 1.00 101.85 ? 54  U   X O4    1 
ATOM   959  C  C5    . U   A 1 357 ? 174.621 184.254 156.168 1.00 101.85 ? 54  U   X C5    1 
ATOM   960  C  C6    . U   A 1 357 ? 173.928 183.199 155.741 1.00 101.85 ? 54  U   X C6    1 
ATOM   961  P  P     . C   A 1 358 ? 169.977 178.022 155.733 1.00 104.79 ? 55  C   X P     1 
ATOM   962  O  OP1   . C   A 1 358 ? 170.356 176.852 156.562 1.00 104.79 ? 55  C   X OP1   1 
ATOM   963  O  OP2   . C   A 1 358 ? 169.093 177.821 154.561 1.00 104.79 ? 55  C   X OP2   1 
ATOM   964  O  "O5'" . C   A 1 358 ? 169.320 179.116 156.687 1.00 104.79 ? 55  C   X "O5'" 1 
ATOM   965  C  "C5'" . C   A 1 358 ? 167.928 179.091 156.986 1.00 104.79 ? 55  C   X "C5'" 1 
ATOM   966  C  "C4'" . C   A 1 358 ? 167.565 177.876 157.797 1.00 104.79 ? 55  C   X "C4'" 1 
ATOM   967  O  "O4'" . C   A 1 358 ? 168.472 177.774 158.926 1.00 104.79 ? 55  C   X "O4'" 1 
ATOM   968  C  "C3'" . C   A 1 358 ? 166.153 177.878 158.384 1.00 104.79 ? 55  C   X "C3'" 1 
ATOM   969  O  "O3'" . C   A 1 358 ? 165.660 176.539 158.456 1.00 104.79 ? 55  C   X "O3'" 1 
ATOM   970  C  "C2'" . C   A 1 358 ? 166.391 178.387 159.798 1.00 104.79 ? 55  C   X "C2'" 1 
ATOM   971  O  "O2'" . C   A 1 358 ? 165.390 178.031 160.726 1.00 104.79 ? 55  C   X "O2'" 1 
ATOM   972  C  "C1'" . C   A 1 358 ? 167.726 177.726 160.124 1.00 104.79 ? 55  C   X "C1'" 1 
ATOM   973  N  N1    . C   A 1 358 ? 168.492 178.389 161.188 1.00 104.79 ? 55  C   X N1    1 
ATOM   974  C  C2    . C   A 1 358 ? 169.435 177.632 161.886 1.00 104.79 ? 55  C   X C2    1 
ATOM   975  O  O2    . C   A 1 358 ? 169.608 176.443 161.566 1.00 104.79 ? 55  C   X O2    1 
ATOM   976  N  N3    . C   A 1 358 ? 170.143 178.217 162.878 1.00 104.79 ? 55  C   X N3    1 
ATOM   977  C  C4    . C   A 1 358 ? 169.924 179.495 163.189 1.00 104.79 ? 55  C   X C4    1 
ATOM   978  N  N4    . C   A 1 358 ? 170.644 180.031 164.177 1.00 104.79 ? 55  C   X N4    1 
ATOM   979  C  C5    . C   A 1 358 ? 168.959 180.285 162.500 1.00 104.79 ? 55  C   X C5    1 
ATOM   980  C  C6    . C   A 1 358 ? 168.268 179.695 161.516 1.00 104.79 ? 55  C   X C6    1 
ATOM   981  P  P     . A   A 1 359 ? 165.777 175.553 157.197 1.00 88.78  ? 56  A   X P     1 
ATOM   982  O  OP1   . A   A 1 359 ? 167.100 174.886 157.246 1.00 88.78  ? 56  A   X OP1   1 
ATOM   983  O  OP2   . A   A 1 359 ? 165.379 176.305 155.987 1.00 88.78  ? 56  A   X OP2   1 
ATOM   984  O  "O5'" . A   A 1 359 ? 164.673 174.439 157.473 1.00 88.78  ? 56  A   X "O5'" 1 
ATOM   985  C  "C5'" . A   A 1 359 ? 163.918 174.431 158.675 1.00 88.78  ? 56  A   X "C5'" 1 
ATOM   986  C  "C4'" . A   A 1 359 ? 162.627 173.674 158.498 1.00 88.78  ? 56  A   X "C4'" 1 
ATOM   987  O  "O4'" . A   A 1 359 ? 161.818 174.331 157.493 1.00 88.78  ? 56  A   X "O4'" 1 
ATOM   988  C  "C3'" . A   A 1 359 ? 162.770 172.250 157.997 1.00 88.78  ? 56  A   X "C3'" 1 
ATOM   989  O  "O3'" . A   A 1 359 ? 163.011 171.338 159.048 1.00 88.78  ? 56  A   X "O3'" 1 
ATOM   990  C  "C2'" . A   A 1 359 ? 161.452 172.005 157.288 1.00 88.78  ? 56  A   X "C2'" 1 
ATOM   991  O  "O2'" . A   A 1 359 ? 160.440 171.703 158.231 1.00 88.78  ? 56  A   X "O2'" 1 
ATOM   992  C  "C1'" . A   A 1 359 ? 161.165 173.379 156.694 1.00 88.78  ? 56  A   X "C1'" 1 
ATOM   993  N  N9    . A   A 1 359 ? 161.706 173.512 155.336 1.00 88.78  ? 56  A   X N9    1 
ATOM   994  C  C8    . A   A 1 359 ? 162.762 174.290 154.980 1.00 88.78  ? 56  A   X C8    1 
ATOM   995  N  N7    . A   A 1 359 ? 163.047 174.238 153.712 1.00 88.78  ? 56  A   X N7    1 
ATOM   996  C  C5    . A   A 1 359 ? 162.117 173.367 153.199 1.00 88.78  ? 56  A   X C5    1 
ATOM   997  C  C6    . A   A 1 359 ? 161.897 172.902 151.905 1.00 88.78  ? 56  A   X C6    1 
ATOM   998  N  N6    . A   A 1 359 ? 162.628 173.257 150.856 1.00 88.78  ? 56  A   X N6    1 
ATOM   999  N  N1    . A   A 1 359 ? 160.894 172.045 151.713 1.00 88.78  ? 56  A   X N1    1 
ATOM   1000 C  C2    . A   A 1 359 ? 160.167 171.700 152.770 1.00 88.78  ? 56  A   X C2    1 
ATOM   1001 N  N3    . A   A 1 359 ? 160.270 172.063 154.038 1.00 88.78  ? 56  A   X N3    1 
ATOM   1002 C  C4    . A   A 1 359 ? 161.282 172.913 154.186 1.00 88.78  ? 56  A   X C4    1 
ATOM   1003 P  P     . C   A 1 360 ? 164.322 170.421 159.032 1.00 87.85  ? 57  C   X P     1 
ATOM   1004 O  OP1   . C   A 1 360 ? 164.205 169.431 160.116 1.00 87.85  ? 57  C   X OP1   1 
ATOM   1005 O  OP2   . C   A 1 360 ? 165.502 171.310 158.956 1.00 87.85  ? 57  C   X OP2   1 
ATOM   1006 O  "O5'" . C   A 1 360 ? 164.189 169.607 157.679 1.00 87.85  ? 57  C   X "O5'" 1 
ATOM   1007 C  "C5'" . C   A 1 360 ? 163.094 168.735 157.473 1.00 87.85  ? 57  C   X "C5'" 1 
ATOM   1008 C  "C4'" . C   A 1 360 ? 162.944 168.402 156.017 1.00 87.85  ? 57  C   X "C4'" 1 
ATOM   1009 O  "O4'" . C   A 1 360 ? 162.756 169.622 155.265 1.00 87.85  ? 57  C   X "O4'" 1 
ATOM   1010 C  "C3'" . C   A 1 360 ? 164.149 167.751 155.371 1.00 87.85  ? 57  C   X "C3'" 1 
ATOM   1011 O  "O3'" . C   A 1 360 ? 164.204 166.360 155.596 1.00 87.85  ? 57  C   X "O3'" 1 
ATOM   1012 C  "C2'" . C   A 1 360 ? 163.983 168.124 153.911 1.00 87.85  ? 57  C   X "C2'" 1 
ATOM   1013 O  "O2'" . C   A 1 360 ? 163.005 167.309 153.294 1.00 87.85  ? 57  C   X "O2'" 1 
ATOM   1014 C  "C1'" . C   A 1 360 ? 163.420 169.534 154.028 1.00 87.85  ? 57  C   X "C1'" 1 
ATOM   1015 N  N1    . C   A 1 360 ? 164.486 170.552 154.012 1.00 87.85  ? 57  C   X N1    1 
ATOM   1016 C  C2    . C   A 1 360 ? 165.163 170.798 152.831 1.00 87.85  ? 57  C   X C2    1 
ATOM   1017 O  O2    . C   A 1 360 ? 164.848 170.141 151.836 1.00 87.85  ? 57  C   X O2    1 
ATOM   1018 N  N3    . C   A 1 360 ? 166.141 171.720 152.811 1.00 87.85  ? 57  C   X N3    1 
ATOM   1019 C  C4    . C   A 1 360 ? 166.437 172.390 153.913 1.00 87.85  ? 57  C   X C4    1 
ATOM   1020 N  N4    . C   A 1 360 ? 167.403 173.296 153.851 1.00 87.85  ? 57  C   X N4    1 
ATOM   1021 C  C5    . C   A 1 360 ? 165.755 172.169 155.131 1.00 87.85  ? 57  C   X C5    1 
ATOM   1022 C  C6    . C   A 1 360 ? 164.792 171.248 155.135 1.00 87.85  ? 57  C   X C6    1 
ATOM   1023 P  P     . C   A 1 361 ? 165.613 165.612 155.575 1.00 89.62  ? 58  C   X P     1 
ATOM   1024 O  OP1   . C   A 1 361 ? 165.444 164.225 156.054 1.00 89.62  ? 58  C   X OP1   1 
ATOM   1025 O  OP2   . C   A 1 361 ? 166.591 166.507 156.219 1.00 89.62  ? 58  C   X OP2   1 
ATOM   1026 O  "O5'" . C   A 1 361 ? 165.952 165.518 154.031 1.00 89.62  ? 58  C   X "O5'" 1 
ATOM   1027 C  "C5'" . C   A 1 361 ? 165.166 164.707 153.180 1.00 89.62  ? 58  C   X "C5'" 1 
ATOM   1028 C  "C4'" . C   A 1 361 ? 165.620 164.830 151.756 1.00 89.62  ? 58  C   X "C4'" 1 
ATOM   1029 O  "O4'" . C   A 1 361 ? 165.530 166.211 151.351 1.00 89.62  ? 58  C   X "O4'" 1 
ATOM   1030 C  "C3'" . C   A 1 361 ? 167.065 164.460 151.497 1.00 89.62  ? 58  C   X "C3'" 1 
ATOM   1031 O  "O3'" . C   A 1 361 ? 167.226 163.070 151.315 1.00 89.62  ? 58  C   X "O3'" 1 
ATOM   1032 C  "C2'" . C   A 1 361 ? 167.393 165.257 150.250 1.00 89.62  ? 58  C   X "C2'" 1 
ATOM   1033 O  "O2'" . C   A 1 361 ? 166.887 164.600 149.102 1.00 89.62  ? 58  C   X "O2'" 1 
ATOM   1034 C  "C1'" . C   A 1 361 ? 166.572 166.520 150.464 1.00 89.62  ? 58  C   X "C1'" 1 
ATOM   1035 N  N1    . C   A 1 361 ? 167.352 167.628 151.038 1.00 89.62  ? 58  C   X N1    1 
ATOM   1036 C  C2    . C   A 1 361 ? 168.312 168.245 150.258 1.00 89.62  ? 58  C   X C2    1 
ATOM   1037 O  O2    . C   A 1 361 ? 168.504 167.824 149.114 1.00 89.62  ? 58  C   X O2    1 
ATOM   1038 N  N3    . C   A 1 361 ? 169.014 169.266 150.770 1.00 89.62  ? 58  C   X N3    1 
ATOM   1039 C  C4    . C   A 1 361 ? 168.770 169.678 152.002 1.00 89.62  ? 58  C   X C4    1 
ATOM   1040 N  N4    . C   A 1 361 ? 169.484 170.693 152.468 1.00 89.62  ? 58  C   X N4    1 
ATOM   1041 C  C5    . C   A 1 361 ? 167.790 169.074 152.817 1.00 89.62  ? 58  C   X C5    1 
ATOM   1042 C  C6    . C   A 1 361 ? 167.100 168.064 152.295 1.00 89.62  ? 58  C   X C6    1 
ATOM   1043 P  P     . U   A 1 362 ? 168.653 162.384 151.537 1.00 93.83  ? 59  U   X P     1 
ATOM   1044 O  OP1   . U   A 1 362 ? 168.520 160.939 151.248 1.00 93.83  ? 59  U   X OP1   1 
ATOM   1045 O  OP2   . U   A 1 362 ? 169.153 162.839 152.853 1.00 93.83  ? 59  U   X OP2   1 
ATOM   1046 O  "O5'" . U   A 1 362 ? 169.572 163.025 150.408 1.00 93.83  ? 59  U   X "O5'" 1 
ATOM   1047 C  "C5'" . U   A 1 362 ? 169.459 162.639 149.049 1.00 93.83  ? 59  U   X "C5'" 1 
ATOM   1048 C  "C4'" . U   A 1 362 ? 170.510 163.324 148.222 1.00 93.83  ? 59  U   X "C4'" 1 
ATOM   1049 O  "O4'" . U   A 1 362 ? 170.358 164.751 148.357 1.00 93.83  ? 59  U   X "O4'" 1 
ATOM   1050 C  "C3'" . U   A 1 362 ? 171.938 163.051 148.654 1.00 93.83  ? 59  U   X "C3'" 1 
ATOM   1051 O  "O3'" . U   A 1 362 ? 172.451 161.879 148.055 1.00 93.83  ? 59  U   X "O3'" 1 
ATOM   1052 C  "C2'" . U   A 1 362 ? 172.689 164.308 148.233 1.00 93.83  ? 59  U   X "C2'" 1 
ATOM   1053 O  "O2'" . U   A 1 362 ? 173.091 164.224 146.876 1.00 93.83  ? 59  U   X "O2'" 1 
ATOM   1054 C  "C1'" . U   A 1 362 ? 171.616 165.380 148.338 1.00 93.83  ? 59  U   X "C1'" 1 
ATOM   1055 N  N1    . U   A 1 362 ? 171.727 166.252 149.523 1.00 93.83  ? 59  U   X N1    1 
ATOM   1056 C  C2    . U   A 1 362 ? 172.623 167.291 149.501 1.00 93.83  ? 59  U   X C2    1 
ATOM   1057 O  O2    . U   A 1 362 ? 173.369 167.479 148.565 1.00 93.83  ? 59  U   X O2    1 
ATOM   1058 N  N3    . U   A 1 362 ? 172.623 168.082 150.621 1.00 93.83  ? 59  U   X N3    1 
ATOM   1059 C  C4    . U   A 1 362 ? 171.807 167.938 151.715 1.00 93.83  ? 59  U   X C4    1 
ATOM   1060 O  O4    . U   A 1 362 ? 171.893 168.708 152.662 1.00 93.83  ? 59  U   X O4    1 
ATOM   1061 C  C5    . U   A 1 362 ? 170.900 166.850 151.650 1.00 93.83  ? 59  U   X C5    1 
ATOM   1062 C  C6    . U   A 1 362 ? 170.883 166.071 150.576 1.00 93.83  ? 59  U   X C6    1 
ATOM   1063 P  P     . G   A 1 363 ? 173.404 160.904 148.888 1.00 97.02  ? 60  G   X P     1 
ATOM   1064 O  OP1   . G   A 1 363 ? 173.675 159.691 148.083 1.00 97.02  ? 60  G   X OP1   1 
ATOM   1065 O  OP2   . G   A 1 363 ? 172.788 160.776 150.225 1.00 97.02  ? 60  G   X OP2   1 
ATOM   1066 O  "O5'" . G   A 1 363 ? 174.760 161.723 149.025 1.00 97.02  ? 60  G   X "O5'" 1 
ATOM   1067 C  "C5'" . G   A 1 363 ? 175.514 162.088 147.881 1.00 97.02  ? 60  G   X "C5'" 1 
ATOM   1068 C  "C4'" . G   A 1 363 ? 176.500 163.179 148.206 1.00 97.02  ? 60  G   X "C4'" 1 
ATOM   1069 O  "O4'" . G   A 1 363 ? 175.774 164.386 148.538 1.00 97.02  ? 60  G   X "O4'" 1 
ATOM   1070 C  "C3'" . G   A 1 363 ? 177.388 162.925 149.412 1.00 97.02  ? 60  G   X "C3'" 1 
ATOM   1071 O  "O3'" . G   A 1 363 ? 178.552 162.192 149.085 1.00 97.02  ? 60  G   X "O3'" 1 
ATOM   1072 C  "C2'" . G   A 1 363 ? 177.716 164.327 149.900 1.00 97.02  ? 60  G   X "C2'" 1 
ATOM   1073 O  "O2'" . G   A 1 363 ? 178.793 164.869 149.153 1.00 97.02  ? 60  G   X "O2'" 1 
ATOM   1074 C  "C1'" . G   A 1 363 ? 176.447 165.097 149.546 1.00 97.02  ? 60  G   X "C1'" 1 
ATOM   1075 N  N9    . G   A 1 363 ? 175.540 165.261 150.696 1.00 97.02  ? 60  G   X N9    1 
ATOM   1076 C  C8    . G   A 1 363 ? 174.562 164.400 151.109 1.00 97.02  ? 60  G   X C8    1 
ATOM   1077 N  N7    . G   A 1 363 ? 173.914 164.820 152.156 1.00 97.02  ? 60  G   X N7    1 
ATOM   1078 C  C5    . G   A 1 363 ? 174.498 166.036 152.444 1.00 97.02  ? 60  G   X C5    1 
ATOM   1079 C  C6    . G   A 1 363 ? 174.212 166.952 153.472 1.00 97.02  ? 60  G   X C6    1 
ATOM   1080 O  O6    . G   A 1 363 ? 173.358 166.874 154.358 1.00 97.02  ? 60  G   X O6    1 
ATOM   1081 N  N1    . G   A 1 363 ? 175.038 168.055 153.404 1.00 97.02  ? 60  G   X N1    1 
ATOM   1082 C  C2    . G   A 1 363 ? 176.013 168.246 152.469 1.00 97.02  ? 60  G   X C2    1 
ATOM   1083 N  N2    . G   A 1 363 ? 176.701 169.381 152.572 1.00 97.02  ? 60  G   X N2    1 
ATOM   1084 N  N3    . G   A 1 363 ? 176.297 167.400 151.506 1.00 97.02  ? 60  G   X N3    1 
ATOM   1085 C  C4    . G   A 1 363 ? 175.503 166.322 151.559 1.00 97.02  ? 60  G   X C4    1 
ATOM   1086 P  P     . A   A 1 364 ? 178.547 160.590 149.038 1.00 99.70  ? 61  A   X P     1 
ATOM   1087 O  OP1   . A   A 1 364 ? 179.928 160.136 149.335 1.00 99.70  ? 61  A   X OP1   1 
ATOM   1088 O  OP2   . A   A 1 364 ? 177.880 160.154 147.789 1.00 99.70  ? 61  A   X OP2   1 
ATOM   1089 O  "O5'" . A   A 1 364 ? 177.608 160.154 150.243 1.00 99.70  ? 61  A   X "O5'" 1 
ATOM   1090 C  "C5'" . A   A 1 364 ? 177.409 158.776 150.533 1.00 99.70  ? 61  A   X "C5'" 1 
ATOM   1091 C  "C4'" . A   A 1 364 ? 176.693 158.579 151.844 1.00 99.70  ? 61  A   X "C4'" 1 
ATOM   1092 O  "O4'" . A   A 1 364 ? 177.173 159.563 152.798 1.00 99.70  ? 61  A   X "O4'" 1 
ATOM   1093 C  "C3'" . A   A 1 364 ? 175.182 158.751 151.787 1.00 99.70  ? 61  A   X "C3'" 1 
ATOM   1094 O  "O3'" . A   A 1 364 ? 174.584 157.916 152.769 1.00 99.70  ? 61  A   X "O3'" 1 
ATOM   1095 C  "C2'" . A   A 1 364 ? 175.002 160.201 152.197 1.00 99.70  ? 61  A   X "C2'" 1 
ATOM   1096 O  "O2'" . A   A 1 364 ? 173.729 160.507 152.720 1.00 99.70  ? 61  A   X "O2'" 1 
ATOM   1097 C  "C1'" . A   A 1 364 ? 176.095 160.360 153.243 1.00 99.70  ? 61  A   X "C1'" 1 
ATOM   1098 N  N9    . A   A 1 364 ? 176.571 161.731 153.370 1.00 99.70  ? 61  A   X N9    1 
ATOM   1099 C  C8    . A   A 1 364 ? 177.632 162.302 152.732 1.00 99.70  ? 61  A   X C8    1 
ATOM   1100 N  N7    . A   A 1 364 ? 177.812 163.556 153.046 1.00 99.70  ? 61  A   X N7    1 
ATOM   1101 C  C5    . A   A 1 364 ? 176.798 163.813 153.948 1.00 99.70  ? 61  A   X C5    1 
ATOM   1102 C  C6    . A   A 1 364 ? 176.447 164.959 154.653 1.00 99.70  ? 61  A   X C6    1 
ATOM   1103 N  N6    . A   A 1 364 ? 177.106 166.107 154.536 1.00 99.70  ? 61  A   X N6    1 
ATOM   1104 N  N1    . A   A 1 364 ? 175.385 164.894 155.477 1.00 99.70  ? 61  A   X N1    1 
ATOM   1105 C  C2    . A   A 1 364 ? 174.731 163.738 155.580 1.00 99.70  ? 61  A   X C2    1 
ATOM   1106 N  N3    . A   A 1 364 ? 174.970 162.586 154.966 1.00 99.70  ? 61  A   X N3    1 
ATOM   1107 C  C4    . A   A 1 364 ? 176.032 162.697 154.162 1.00 99.70  ? 61  A   X C4    1 
ATOM   1108 P  P     . U   A 1 365 ? 173.229 157.128 152.439 1.00 107.40 ? 62  U   X P     1 
ATOM   1109 O  OP1   . U   A 1 365 ? 173.351 156.545 151.081 1.00 107.40 ? 62  U   X OP1   1 
ATOM   1110 O  OP2   . U   A 1 365 ? 172.091 158.021 152.762 1.00 107.40 ? 62  U   X OP2   1 
ATOM   1111 O  "O5'" . U   A 1 365 ? 173.229 155.946 153.501 1.00 107.40 ? 62  U   X "O5'" 1 
ATOM   1112 C  "C5'" . U   A 1 365 ? 173.683 156.176 154.830 1.00 107.40 ? 62  U   X "C5'" 1 
ATOM   1113 C  "C4'" . U   A 1 365 ? 174.938 155.398 155.138 1.00 107.40 ? 62  U   X "C4'" 1 
ATOM   1114 O  "O4'" . U   A 1 365 ? 174.839 154.074 154.548 1.00 107.40 ? 62  U   X "O4'" 1 
ATOM   1115 C  "C3'" . U   A 1 365 ? 176.234 155.999 154.604 1.00 107.40 ? 62  U   X "C3'" 1 
ATOM   1116 O  "O3'" . U   A 1 365 ? 177.296 155.660 155.488 1.00 107.40 ? 62  U   X "O3'" 1 
ATOM   1117 C  "C2'" . U   A 1 365 ? 176.430 155.247 153.298 1.00 107.40 ? 62  U   X "C2'" 1 
ATOM   1118 O  "O2'" . U   A 1 365 ? 177.762 155.213 152.834 1.00 107.40 ? 62  U   X "O2'" 1 
ATOM   1119 C  "C1'" . U   A 1 365 ? 175.935 153.860 153.682 1.00 107.40 ? 62  U   X "C1'" 1 
ATOM   1120 N  N1    . U   A 1 365 ? 175.472 153.060 152.546 1.00 107.40 ? 62  U   X N1    1 
ATOM   1121 C  C2    . U   A 1 365 ? 176.159 151.900 152.283 1.00 107.40 ? 62  U   X C2    1 
ATOM   1122 O  O2    . U   A 1 365 ? 177.110 151.538 152.951 1.00 107.40 ? 62  U   X O2    1 
ATOM   1123 N  N3    . U   A 1 365 ? 175.688 151.189 151.211 1.00 107.40 ? 62  U   X N3    1 
ATOM   1124 C  C4    . U   A 1 365 ? 174.623 151.524 150.401 1.00 107.40 ? 62  U   X C4    1 
ATOM   1125 O  O4    . U   A 1 365 ? 174.317 150.782 149.470 1.00 107.40 ? 62  U   X O4    1 
ATOM   1126 C  C5    . U   A 1 365 ? 173.965 152.745 150.742 1.00 107.40 ? 62  U   X C5    1 
ATOM   1127 C  C6    . U   A 1 365 ? 174.404 153.455 151.780 1.00 107.40 ? 62  U   X C6    1 
ATOM   1128 P  P     . C   A 1 366 ? 177.814 156.711 156.580 1.00 99.08  ? 63  C   X P     1 
ATOM   1129 O  OP1   . C   A 1 366 ? 178.966 156.086 157.269 1.00 99.08  ? 63  C   X OP1   1 
ATOM   1130 O  OP2   . C   A 1 366 ? 176.651 157.201 157.357 1.00 99.08  ? 63  C   X OP2   1 
ATOM   1131 O  "O5'" . C   A 1 366 ? 178.338 157.934 155.712 1.00 99.08  ? 63  C   X "O5'" 1 
ATOM   1132 C  "C5'" . C   A 1 366 ? 179.454 157.795 154.850 1.00 99.08  ? 63  C   X "C5'" 1 
ATOM   1133 C  "C4'" . C   A 1 366 ? 180.378 158.974 154.973 1.00 99.08  ? 63  C   X "C4'" 1 
ATOM   1134 O  "O4'" . C   A 1 366 ? 179.633 160.200 154.772 1.00 99.08  ? 63  C   X "O4'" 1 
ATOM   1135 C  "C3'" . C   A 1 366 ? 181.028 159.151 156.332 1.00 99.08  ? 63  C   X "C3'" 1 
ATOM   1136 O  "O3'" . C   A 1 366 ? 182.175 158.334 156.477 1.00 99.08  ? 63  C   X "O3'" 1 
ATOM   1137 C  "C2'" . C   A 1 366 ? 181.343 160.640 156.369 1.00 99.08  ? 63  C   X "C2'" 1 
ATOM   1138 O  "O2'" . C   A 1 366 ? 182.564 160.901 155.698 1.00 99.08  ? 63  C   X "O2'" 1 
ATOM   1139 C  "C1'" . C   A 1 366 ? 180.193 161.234 155.547 1.00 99.08  ? 63  C   X "C1'" 1 
ATOM   1140 N  N1    . C   A 1 366 ? 179.131 161.836 156.382 1.00 99.08  ? 63  C   X N1    1 
ATOM   1141 C  C2    . C   A 1 366 ? 179.349 163.070 156.994 1.00 99.08  ? 63  C   X C2    1 
ATOM   1142 O  O2    . C   A 1 366 ? 180.438 163.629 156.837 1.00 99.08  ? 63  C   X O2    1 
ATOM   1143 N  N3    . C   A 1 366 ? 178.380 163.622 157.748 1.00 99.08  ? 63  C   X N3    1 
ATOM   1144 C  C4    . C   A 1 366 ? 177.226 162.992 157.895 1.00 99.08  ? 63  C   X C4    1 
ATOM   1145 N  N4    . C   A 1 366 ? 176.287 163.563 158.646 1.00 99.08  ? 63  C   X N4    1 
ATOM   1146 C  C5    . C   A 1 366 ? 176.971 161.741 157.280 1.00 99.08  ? 63  C   X C5    1 
ATOM   1147 C  C6    . C   A 1 366 ? 177.938 161.205 156.533 1.00 99.08  ? 63  C   X C6    1 
ATOM   1148 P  P     . U   A 1 367 ? 182.683 157.879 157.929 1.00 96.87  ? 64  U   X P     1 
ATOM   1149 O  OP1   . U   A 1 367 ? 183.819 156.952 157.722 1.00 96.87  ? 64  U   X OP1   1 
ATOM   1150 O  OP2   . U   A 1 367 ? 181.519 157.429 158.726 1.00 96.87  ? 64  U   X OP2   1 
ATOM   1151 O  "O5'" . U   A 1 367 ? 183.256 159.216 158.576 1.00 96.87  ? 64  U   X "O5'" 1 
ATOM   1152 C  "C5'" . U   A 1 367 ? 184.498 159.755 158.152 1.00 96.87  ? 64  U   X "C5'" 1 
ATOM   1153 C  "C4'" . U   A 1 367 ? 184.906 160.953 158.976 1.00 96.87  ? 64  U   X "C4'" 1 
ATOM   1154 O  "O4'" . U   A 1 367 ? 184.064 162.088 158.651 1.00 96.87  ? 64  U   X "O4'" 1 
ATOM   1155 C  "C3'" . U   A 1 367 ? 184.776 160.820 160.484 1.00 96.87  ? 64  U   X "C3'" 1 
ATOM   1156 O  "O3'" . U   A 1 367 ? 185.856 160.120 161.074 1.00 96.87  ? 64  U   X "O3'" 1 
ATOM   1157 C  "C2'" . U   A 1 367 ? 184.689 162.270 160.925 1.00 96.87  ? 64  U   X "C2'" 1 
ATOM   1158 O  "O2'" . U   A 1 367 ? 185.971 162.869 160.881 1.00 96.87  ? 64  U   X "O2'" 1 
ATOM   1159 C  "C1'" . U   A 1 367 ? 183.855 162.874 159.800 1.00 96.87  ? 64  U   X "C1'" 1 
ATOM   1160 N  N1    . U   A 1 367 ? 182.413 162.857 160.121 1.00 96.87  ? 64  U   X N1    1 
ATOM   1161 C  C2    . U   A 1 367 ? 181.915 163.845 160.934 1.00 96.87  ? 64  U   X C2    1 
ATOM   1162 O  O2    . U   A 1 367 ? 182.613 164.727 161.382 1.00 96.87  ? 64  U   X O2    1 
ATOM   1163 N  N3    . U   A 1 367 ? 180.572 163.767 161.191 1.00 96.87  ? 64  U   X N3    1 
ATOM   1164 C  C4    . U   A 1 367 ? 179.700 162.813 160.727 1.00 96.87  ? 64  U   X C4    1 
ATOM   1165 O  O4    . U   A 1 367 ? 178.512 162.861 161.040 1.00 96.87  ? 64  U   X O4    1 
ATOM   1166 C  C5    . U   A 1 367 ? 180.292 161.820 159.896 1.00 96.87  ? 64  U   X C5    1 
ATOM   1167 C  C6    . U   A 1 367 ? 181.594 161.878 159.628 1.00 96.87  ? 64  U   X C6    1 
ATOM   1168 P  P     . G   A 1 368 ? 185.632 159.236 162.396 1.00 94.90  ? 65  G   X P     1 
ATOM   1169 O  OP1   . G   A 1 368 ? 186.875 158.479 162.661 1.00 94.90  ? 65  G   X OP1   1 
ATOM   1170 O  OP2   . G   A 1 368 ? 184.361 158.493 162.253 1.00 94.90  ? 65  G   X OP2   1 
ATOM   1171 O  "O5'" . G   A 1 368 ? 185.465 160.306 163.564 1.00 94.90  ? 65  G   X "O5'" 1 
ATOM   1172 C  "C5'" . G   A 1 368 ? 186.600 160.880 164.194 1.00 94.90  ? 65  G   X "C5'" 1 
ATOM   1173 C  "C4'" . G   A 1 368 ? 186.220 161.960 165.175 1.00 94.90  ? 65  G   X "C4'" 1 
ATOM   1174 O  "O4'" . G   A 1 368 ? 185.369 162.934 164.528 1.00 94.90  ? 65  G   X "O4'" 1 
ATOM   1175 C  "C3'" . G   A 1 368 ? 185.417 161.528 166.387 1.00 94.90  ? 65  G   X "C3'" 1 
ATOM   1176 O  "O3'" . G   A 1 368 ? 186.213 160.965 167.416 1.00 94.90  ? 65  G   X "O3'" 1 
ATOM   1177 C  "C2'" . G   A 1 368 ? 184.749 162.823 166.799 1.00 94.90  ? 65  G   X "C2'" 1 
ATOM   1178 O  "O2'" . G   A 1 368 ? 185.689 163.671 167.432 1.00 94.90  ? 65  G   X "O2'" 1 
ATOM   1179 C  "C1'" . G   A 1 368 ? 184.423 163.426 165.444 1.00 94.90  ? 65  G   X "C1'" 1 
ATOM   1180 N  N9    . G   A 1 368 ? 183.088 163.031 164.984 1.00 94.90  ? 65  G   X N9    1 
ATOM   1181 C  C8    . G   A 1 368 ? 182.802 162.212 163.932 1.00 94.90  ? 65  G   X C8    1 
ATOM   1182 N  N7    . G   A 1 368 ? 181.526 162.043 163.750 1.00 94.90  ? 65  G   X N7    1 
ATOM   1183 C  C5    . G   A 1 368 ? 180.936 162.800 164.744 1.00 94.90  ? 65  G   X C5    1 
ATOM   1184 C  C6    . G   A 1 368 ? 179.573 162.998 165.060 1.00 94.90  ? 65  G   X C6    1 
ATOM   1185 O  O6    . G   A 1 368 ? 178.575 162.543 164.495 1.00 94.90  ? 65  G   X O6    1 
ATOM   1186 N  N1    . G   A 1 368 ? 179.410 163.843 166.142 1.00 94.90  ? 65  G   X N1    1 
ATOM   1187 C  C2    . G   A 1 368 ? 180.439 164.407 166.842 1.00 94.90  ? 65  G   X C2    1 
ATOM   1188 N  N2    . G   A 1 368 ? 180.111 165.194 167.873 1.00 94.90  ? 65  G   X N2    1 
ATOM   1189 N  N3    . G   A 1 368 ? 181.712 164.222 166.561 1.00 94.90  ? 65  G   X N3    1 
ATOM   1190 C  C4    . G   A 1 368 ? 181.887 163.414 165.510 1.00 94.90  ? 65  G   X C4    1 
ATOM   1191 P  P     . G   A 1 369 ? 185.582 159.917 168.465 1.00 94.83  ? 66  G   X P     1 
ATOM   1192 O  OP1   . G   A 1 369 ? 186.660 159.501 169.391 1.00 94.83  ? 66  G   X OP1   1 
ATOM   1193 O  OP2   . G   A 1 369 ? 184.834 158.884 167.711 1.00 94.83  ? 66  G   X OP2   1 
ATOM   1194 O  "O5'" . G   A 1 369 ? 184.536 160.765 169.316 1.00 94.83  ? 66  G   X "O5'" 1 
ATOM   1195 C  "C5'" . G   A 1 369 ? 184.969 161.706 170.286 1.00 94.83  ? 66  G   X "C5'" 1 
ATOM   1196 C  "C4'" . G   A 1 369 ? 183.804 162.362 170.983 1.00 94.83  ? 66  G   X "C4'" 1 
ATOM   1197 O  "O4'" . G   A 1 369 ? 182.980 163.060 170.020 1.00 94.83  ? 66  G   X "O4'" 1 
ATOM   1198 C  "C3'" . G   A 1 369 ? 182.835 161.428 171.681 1.00 94.83  ? 66  G   X "C3'" 1 
ATOM   1199 O  "O3'" . G   A 1 369 ? 183.287 161.018 172.957 1.00 94.83  ? 66  G   X "O3'" 1 
ATOM   1200 C  "C2'" . G   A 1 369 ? 181.569 162.259 171.741 1.00 94.83  ? 66  G   X "C2'" 1 
ATOM   1201 O  "O2'" . G   A 1 369 ? 181.673 163.216 172.777 1.00 94.83  ? 66  G   X "O2'" 1 
ATOM   1202 C  "C1'" . G   A 1 369 ? 181.629 162.997 170.412 1.00 94.83  ? 66  G   X "C1'" 1 
ATOM   1203 N  N9    . G   A 1 369 ? 180.858 162.310 169.365 1.00 94.83  ? 66  G   X N9    1 
ATOM   1204 C  C8    . G   A 1 369 ? 181.336 161.534 168.350 1.00 94.83  ? 66  G   X C8    1 
ATOM   1205 N  N7    . G   A 1 369 ? 180.403 161.064 167.574 1.00 94.83  ? 66  G   X N7    1 
ATOM   1206 C  C5    . G   A 1 369 ? 179.234 161.557 168.115 1.00 94.83  ? 66  G   X C5    1 
ATOM   1207 C  C6    . G   A 1 369 ? 177.894 161.390 167.706 1.00 94.83  ? 66  G   X C6    1 
ATOM   1208 O  O6    . G   A 1 369 ? 177.461 160.745 166.750 1.00 94.83  ? 66  G   X O6    1 
ATOM   1209 N  N1    . G   A 1 369 ? 177.013 162.067 168.533 1.00 94.83  ? 66  G   X N1    1 
ATOM   1210 C  C2    . G   A 1 369 ? 177.384 162.802 169.620 1.00 94.83  ? 66  G   X C2    1 
ATOM   1211 N  N2    . G   A 1 369 ? 176.404 163.392 170.302 1.00 94.83  ? 66  G   X N2    1 
ATOM   1212 N  N3    . G   A 1 369 ? 178.631 162.975 170.010 1.00 94.83  ? 66  G   X N3    1 
ATOM   1213 C  C4    . G   A 1 369 ? 179.499 162.327 169.217 1.00 94.83  ? 66  G   X C4    1 
ATOM   1214 P  P     . A   A 1 370 ? 182.832 159.601 173.561 1.00 97.57  ? 67  A   X P     1 
ATOM   1215 O  OP1   . A   A 1 370 ? 183.501 159.425 174.872 1.00 97.57  ? 67  A   X OP1   1 
ATOM   1216 O  OP2   . A   A 1 370 ? 182.984 158.569 172.504 1.00 97.57  ? 67  A   X OP2   1 
ATOM   1217 O  "O5'" . A   A 1 370 ? 181.286 159.793 173.871 1.00 97.57  ? 67  A   X "O5'" 1 
ATOM   1218 C  "C5'" . A   A 1 370 ? 180.873 160.735 174.842 1.00 97.57  ? 67  A   X "C5'" 1 
ATOM   1219 C  "C4'" . A   A 1 370 ? 179.383 160.922 174.829 1.00 97.57  ? 67  A   X "C4'" 1 
ATOM   1220 O  "O4'" . A   A 1 370 ? 178.956 161.355 173.518 1.00 97.57  ? 67  A   X "O4'" 1 
ATOM   1221 C  "C3'" . A   A 1 370 ? 178.565 159.673 175.086 1.00 97.57  ? 67  A   X "C3'" 1 
ATOM   1222 O  "O3'" . A   A 1 370 ? 178.454 159.363 176.460 1.00 97.57  ? 67  A   X "O3'" 1 
ATOM   1223 C  "C2'" . A   A 1 370 ? 177.241 160.019 174.439 1.00 97.57  ? 67  A   X "C2'" 1 
ATOM   1224 O  "O2'" . A   A 1 370 ? 176.503 160.904 175.267 1.00 97.57  ? 67  A   X "O2'" 1 
ATOM   1225 C  "C1'" . A   A 1 370 ? 177.703 160.790 173.214 1.00 97.57  ? 67  A   X "C1'" 1 
ATOM   1226 N  N9    . A   A 1 370 ? 177.879 159.917 172.049 1.00 97.57  ? 67  A   X N9    1 
ATOM   1227 C  C8    . A   A 1 370 ? 179.015 159.268 171.674 1.00 97.57  ? 67  A   X C8    1 
ATOM   1228 N  N7    . A   A 1 370 ? 178.884 158.567 170.578 1.00 97.57  ? 67  A   X N7    1 
ATOM   1229 C  C5    . A   A 1 370 ? 177.570 158.777 170.217 1.00 97.57  ? 67  A   X C5    1 
ATOM   1230 C  C6    . A   A 1 370 ? 176.814 158.308 169.141 1.00 97.57  ? 67  A   X C6    1 
ATOM   1231 N  N6    . A   A 1 370 ? 177.299 157.502 168.198 1.00 97.57  ? 67  A   X N6    1 
ATOM   1232 N  N1    . A   A 1 370 ? 175.532 158.704 169.067 1.00 97.57  ? 67  A   X N1    1 
ATOM   1233 C  C2    . A   A 1 370 ? 175.066 159.504 170.027 1.00 97.57  ? 67  A   X C2    1 
ATOM   1234 N  N3    . A   A 1 370 ? 175.679 160.021 171.078 1.00 97.57  ? 67  A   X N3    1 
ATOM   1235 C  C4    . A   A 1 370 ? 176.944 159.606 171.115 1.00 97.57  ? 67  A   X C4    1 
ATOM   1236 P  P     . U   A 1 371 ? 178.447 157.836 176.939 1.00 97.70  ? 68  U   X P     1 
ATOM   1237 O  OP1   . U   A 1 371 ? 178.536 157.810 178.418 1.00 97.70  ? 68  U   X OP1   1 
ATOM   1238 O  OP2   . U   A 1 371 ? 179.454 157.117 176.121 1.00 97.70  ? 68  U   X OP2   1 
ATOM   1239 O  "O5'" . U   A 1 371 ? 176.996 157.329 176.536 1.00 97.70  ? 68  U   X "O5'" 1 
ATOM   1240 C  "C5'" . U   A 1 371 ? 175.851 158.024 176.989 1.00 97.70  ? 68  U   X "C5'" 1 
ATOM   1241 C  "C4'" . U   A 1 371 ? 174.650 157.756 176.121 1.00 97.70  ? 68  U   X "C4'" 1 
ATOM   1242 O  "O4'" . U   A 1 371 ? 174.915 158.152 174.757 1.00 97.70  ? 68  U   X "O4'" 1 
ATOM   1243 C  "C3'" . U   A 1 371 ? 174.212 156.312 175.993 1.00 97.70  ? 68  U   X "C3'" 1 
ATOM   1244 O  "O3'" . U   A 1 371 ? 173.491 155.860 177.122 1.00 97.70  ? 68  U   X "O3'" 1 
ATOM   1245 C  "C2'" . U   A 1 371 ? 173.387 156.338 174.714 1.00 97.70  ? 68  U   X "C2'" 1 
ATOM   1246 O  "O2'" . U   A 1 371 ? 172.099 156.871 174.971 1.00 97.70  ? 68  U   X "O2'" 1 
ATOM   1247 C  "C1'" . U   A 1 371 ? 174.158 157.356 173.875 1.00 97.70  ? 68  U   X "C1'" 1 
ATOM   1248 N  N1    . U   A 1 371 ? 175.064 156.722 172.896 1.00 97.70  ? 68  U   X N1    1 
ATOM   1249 C  C2    . U   A 1 371 ? 174.594 156.631 171.615 1.00 97.70  ? 68  U   X C2    1 
ATOM   1250 O  O2    . U   A 1 371 ? 173.502 157.052 171.310 1.00 97.70  ? 68  U   X O2    1 
ATOM   1251 N  N3    . U   A 1 371 ? 175.429 156.050 170.708 1.00 97.70  ? 68  U   X N3    1 
ATOM   1252 C  C4    . U   A 1 371 ? 176.680 155.554 170.960 1.00 97.70  ? 68  U   X C4    1 
ATOM   1253 O  O4    . U   A 1 371 ? 177.321 155.054 170.040 1.00 97.70  ? 68  U   X O4    1 
ATOM   1254 C  C5    . U   A 1 371 ? 177.102 155.683 172.318 1.00 97.70  ? 68  U   X C5    1 
ATOM   1255 C  C6    . U   A 1 371 ? 176.302 156.252 173.222 1.00 97.70  ? 68  U   X C6    1 
ATOM   1256 P  P     . A   A 1 372 ? 173.821 154.427 177.751 1.00 99.74  ? 69  A   X P     1 
ATOM   1257 O  OP1   . A   A 1 372 ? 172.818 154.135 178.798 1.00 99.74  ? 69  A   X OP1   1 
ATOM   1258 O  OP2   . A   A 1 372 ? 175.261 154.392 178.077 1.00 99.74  ? 69  A   X OP2   1 
ATOM   1259 O  "O5'" . A   A 1 372 ? 173.583 153.436 176.536 1.00 99.74  ? 69  A   X "O5'" 1 
ATOM   1260 C  "C5'" . A   A 1 372 ? 173.733 152.035 176.685 1.00 99.74  ? 69  A   X "C5'" 1 
ATOM   1261 C  "C4'" . A   A 1 372 ? 172.845 151.314 175.709 1.00 99.74  ? 69  A   X "C4'" 1 
ATOM   1262 O  "O4'" . A   A 1 372 ? 171.475 151.408 176.152 1.00 99.74  ? 69  A   X "O4'" 1 
ATOM   1263 C  "C3'" . A   A 1 372 ? 172.834 151.899 174.310 1.00 99.74  ? 69  A   X "C3'" 1 
ATOM   1264 O  "O3'" . A   A 1 372 ? 173.890 151.389 173.528 1.00 99.74  ? 69  A   X "O3'" 1 
ATOM   1265 C  "C2'" . A   A 1 372 ? 171.457 151.527 173.777 1.00 99.74  ? 69  A   X "C2'" 1 
ATOM   1266 O  "O2'" . A   A 1 372 ? 171.464 150.211 173.254 1.00 99.74  ? 69  A   X "O2'" 1 
ATOM   1267 C  "C1'" . A   A 1 372 ? 170.613 151.525 175.047 1.00 99.74  ? 69  A   X "C1'" 1 
ATOM   1268 N  N9    . A   A 1 372 ? 169.778 152.723 175.229 1.00 99.74  ? 69  A   X N9    1 
ATOM   1269 C  C8    . A   A 1 372 ? 169.859 153.628 176.246 1.00 99.74  ? 69  A   X C8    1 
ATOM   1270 N  N7    . A   A 1 372 ? 168.959 154.568 176.188 1.00 99.74  ? 69  A   X N7    1 
ATOM   1271 C  C5    . A   A 1 372 ? 168.230 154.244 175.067 1.00 99.74  ? 69  A   X C5    1 
ATOM   1272 C  C6    . A   A 1 372 ? 167.128 154.849 174.469 1.00 99.74  ? 69  A   X C6    1 
ATOM   1273 N  N6    . A   A 1 372 ? 166.556 155.956 174.936 1.00 99.74  ? 69  A   X N6    1 
ATOM   1274 N  N1    . A   A 1 372 ? 166.630 154.285 173.357 1.00 99.74  ? 69  A   X N1    1 
ATOM   1275 C  C2    . A   A 1 372 ? 167.207 153.178 172.895 1.00 99.74  ? 69  A   X C2    1 
ATOM   1276 N  N3    . A   A 1 372 ? 168.247 152.512 173.374 1.00 99.74  ? 69  A   X N3    1 
ATOM   1277 C  C4    . A   A 1 372 ? 168.711 153.108 174.473 1.00 99.74  ? 69  A   X C4    1 
ATOM   1278 P  P     . A   A 1 373 ? 174.641 152.325 172.474 1.00 96.46  ? 70  A   X P     1 
ATOM   1279 O  OP1   . A   A 1 373 ? 175.747 151.539 171.887 1.00 96.46  ? 70  A   X OP1   1 
ATOM   1280 O  OP2   . A   A 1 373 ? 174.905 153.640 173.094 1.00 96.46  ? 70  A   X OP2   1 
ATOM   1281 O  "O5'" . A   A 1 373 ? 173.555 152.543 171.344 1.00 96.46  ? 70  A   X "O5'" 1 
ATOM   1282 C  "C5'" . A   A 1 373 ? 173.169 151.476 170.500 1.00 96.46  ? 70  A   X "C5'" 1 
ATOM   1283 C  "C4'" . A   A 1 373 ? 172.113 151.938 169.541 1.00 96.46  ? 70  A   X "C4'" 1 
ATOM   1284 O  "O4'" . A   A 1 373 ? 170.874 152.142 170.258 1.00 96.46  ? 70  A   X "O4'" 1 
ATOM   1285 C  "C3'" . A   A 1 373 ? 172.387 153.279 168.895 1.00 96.46  ? 70  A   X "C3'" 1 
ATOM   1286 O  "O3'" . A   A 1 373 ? 173.250 153.179 167.783 1.00 96.46  ? 70  A   X "O3'" 1 
ATOM   1287 C  "C2'" . A   A 1 373 ? 170.996 153.772 168.549 1.00 96.46  ? 70  A   X "C2'" 1 
ATOM   1288 O  "O2'" . A   A 1 373 ? 170.520 153.131 167.380 1.00 96.46  ? 70  A   X "O2'" 1 
ATOM   1289 C  "C1'" . A   A 1 373 ? 170.191 153.255 169.731 1.00 96.46  ? 70  A   X "C1'" 1 
ATOM   1290 N  N9    . A   A 1 373 ? 170.054 154.259 170.794 1.00 96.46  ? 70  A   X N9    1 
ATOM   1291 C  C8    . A   A 1 373 ? 170.902 154.476 171.835 1.00 96.46  ? 70  A   X C8    1 
ATOM   1292 N  N7    . A   A 1 373 ? 170.511 155.435 172.631 1.00 96.46  ? 70  A   X N7    1 
ATOM   1293 C  C5    . A   A 1 373 ? 169.329 155.871 172.077 1.00 96.46  ? 70  A   X C5    1 
ATOM   1294 C  C6    . A   A 1 373 ? 168.435 156.870 172.459 1.00 96.46  ? 70  A   X C6    1 
ATOM   1295 N  N6    . A   A 1 373 ? 168.606 157.630 173.536 1.00 96.46  ? 70  A   X N6    1 
ATOM   1296 N  N1    . A   A 1 373 ? 167.345 157.061 171.706 1.00 96.46  ? 70  A   X N1    1 
ATOM   1297 C  C2    . A   A 1 373 ? 167.187 156.288 170.634 1.00 96.46  ? 70  A   X C2    1 
ATOM   1298 N  N3    . A   A 1 373 ? 167.963 155.314 170.167 1.00 96.46  ? 70  A   X N3    1 
ATOM   1299 C  C4    . A   A 1 373 ? 169.035 155.158 170.944 1.00 96.46  ? 70  A   X C4    1 
ATOM   1300 P  P     . U   A 1 374 ? 174.075 154.460 167.293 1.00 94.80  ? 71  U   X P     1 
ATOM   1301 O  OP1   . U   A 1 374 ? 175.130 153.990 166.361 1.00 94.80  ? 71  U   X OP1   1 
ATOM   1302 O  OP2   . U   A 1 374 ? 174.431 155.265 168.486 1.00 94.80  ? 71  U   X OP2   1 
ATOM   1303 O  "O5'" . U   A 1 374 ? 173.012 155.286 166.454 1.00 94.80  ? 71  U   X "O5'" 1 
ATOM   1304 C  "C5'" . U   A 1 374 ? 172.351 154.692 165.352 1.00 94.80  ? 71  U   X "C5'" 1 
ATOM   1305 C  "C4'" . U   A 1 374 ? 171.141 155.488 164.954 1.00 94.80  ? 71  U   X "C4'" 1 
ATOM   1306 O  "O4'" . U   A 1 374 ? 170.203 155.528 166.049 1.00 94.80  ? 71  U   X "O4'" 1 
ATOM   1307 C  "C3'" . U   A 1 374 ? 171.392 156.946 164.626 1.00 94.80  ? 71  U   X "C3'" 1 
ATOM   1308 O  "O3'" . U   A 1 374 ? 171.853 157.117 163.299 1.00 94.80  ? 71  U   X "O3'" 1 
ATOM   1309 C  "C2'" . U   A 1 374 ? 170.039 157.590 164.884 1.00 94.80  ? 71  U   X "C2'" 1 
ATOM   1310 O  "O2'" . U   A 1 374 ? 169.179 157.404 163.773 1.00 94.80  ? 71  U   X "O2'" 1 
ATOM   1311 C  "C1'" . U   A 1 374 ? 169.509 156.751 166.044 1.00 94.80  ? 71  U   X "C1'" 1 
ATOM   1312 N  N1    . U   A 1 374 ? 169.687 157.401 167.359 1.00 94.80  ? 71  U   X N1    1 
ATOM   1313 C  C2    . U   A 1 374 ? 168.695 158.237 167.795 1.00 94.80  ? 71  U   X C2    1 
ATOM   1314 O  O2    . U   A 1 374 ? 167.706 158.466 167.133 1.00 94.80  ? 71  U   X O2    1 
ATOM   1315 N  N3    . U   A 1 374 ? 168.899 158.802 169.021 1.00 94.80  ? 71  U   X N3    1 
ATOM   1316 C  C4    . U   A 1 374 ? 169.980 158.611 169.842 1.00 94.80  ? 71  U   X C4    1 
ATOM   1317 O  O4    . U   A 1 374 ? 170.040 159.185 170.922 1.00 94.80  ? 71  U   X O4    1 
ATOM   1318 C  C5    . U   A 1 374 ? 170.960 157.728 169.327 1.00 94.80  ? 71  U   X C5    1 
ATOM   1319 C  C6    . U   A 1 374 ? 170.781 157.169 168.134 1.00 94.80  ? 71  U   X C6    1 
ATOM   1320 P  P     . G   A 1 375 ? 172.684 158.420 162.892 1.00 91.48  ? 72  G   X P     1 
ATOM   1321 O  OP1   . G   A 1 375 ? 173.161 158.238 161.506 1.00 91.48  ? 72  G   X OP1   1 
ATOM   1322 O  OP2   . G   A 1 375 ? 173.669 158.687 163.956 1.00 91.48  ? 72  G   X OP2   1 
ATOM   1323 O  "O5'" . G   A 1 375 ? 171.598 159.579 162.895 1.00 91.48  ? 72  G   X "O5'" 1 
ATOM   1324 C  "C5'" . G   A 1 375 ? 171.993 160.939 162.960 1.00 91.48  ? 72  G   X "C5'" 1 
ATOM   1325 C  "C4'" . G   A 1 375 ? 170.894 161.851 162.490 1.00 91.48  ? 72  G   X "C4'" 1 
ATOM   1326 O  "O4'" . G   A 1 375 ? 170.599 161.580 161.100 1.00 91.48  ? 72  G   X "O4'" 1 
ATOM   1327 C  "C3'" . G   A 1 375 ? 169.560 161.686 163.188 1.00 91.48  ? 72  G   X "C3'" 1 
ATOM   1328 O  "O3'" . G   A 1 375 ? 169.497 162.383 164.413 1.00 91.48  ? 72  G   X "O3'" 1 
ATOM   1329 C  "C2'" . G   A 1 375 ? 168.576 162.208 162.158 1.00 91.48  ? 72  G   X "C2'" 1 
ATOM   1330 O  "O2'" . G   A 1 375 ? 168.555 163.626 162.165 1.00 91.48  ? 72  G   X "O2'" 1 
ATOM   1331 C  "C1'" . G   A 1 375 ? 169.221 161.745 160.858 1.00 91.48  ? 72  G   X "C1'" 1 
ATOM   1332 N  N9    . G   A 1 375 ? 168.676 160.458 160.413 1.00 91.48  ? 72  G   X N9    1 
ATOM   1333 C  C8    . G   A 1 375 ? 169.230 159.235 160.657 1.00 91.48  ? 72  G   X C8    1 
ATOM   1334 N  N7    . G   A 1 375 ? 168.541 158.258 160.150 1.00 91.48  ? 72  G   X N7    1 
ATOM   1335 C  C5    . G   A 1 375 ? 167.472 158.881 159.538 1.00 91.48  ? 72  G   X C5    1 
ATOM   1336 C  C6    . G   A 1 375 ? 166.390 158.324 158.822 1.00 91.48  ? 72  G   X C6    1 
ATOM   1337 O  O6    . G   A 1 375 ? 166.159 157.135 158.580 1.00 91.48  ? 72  G   X O6    1 
ATOM   1338 N  N1    . G   A 1 375 ? 165.524 159.300 158.362 1.00 91.48  ? 72  G   X N1    1 
ATOM   1339 C  C2    . G   A 1 375 ? 165.679 160.639 158.569 1.00 91.48  ? 72  G   X C2    1 
ATOM   1340 N  N2    . G   A 1 375 ? 164.726 161.414 158.044 1.00 91.48  ? 72  G   X N2    1 
ATOM   1341 N  N3    . G   A 1 375 ? 166.684 161.174 159.237 1.00 91.48  ? 72  G   X N3    1 
ATOM   1342 C  C4    . G   A 1 375 ? 167.536 160.240 159.692 1.00 91.48  ? 72  G   X C4    1 
ATOM   1343 P  P     . C   A 1 376 ? 168.181 162.288 165.320 1.00 90.31  ? 73  C   X P     1 
ATOM   1344 O  OP1   . C   A 1 376 ? 167.586 160.958 165.090 1.00 90.31  ? 73  C   X OP1   1 
ATOM   1345 O  OP2   . C   A 1 376 ? 167.369 163.508 165.139 1.00 90.31  ? 73  C   X OP2   1 
ATOM   1346 O  "O5'" . C   A 1 376 ? 168.752 162.327 166.796 1.00 90.31  ? 73  C   X "O5'" 1 
ATOM   1347 C  "C5'" . C   A 1 376 ? 168.025 162.945 167.837 1.00 90.31  ? 73  C   X "C5'" 1 
ATOM   1348 C  "C4'" . C   A 1 376 ? 168.951 163.398 168.927 1.00 90.31  ? 73  C   X "C4'" 1 
ATOM   1349 O  "O4'" . C   A 1 376 ? 169.749 162.278 169.376 1.00 90.31  ? 73  C   X "O4'" 1 
ATOM   1350 C  "C3'" . C   A 1 376 ? 169.973 164.436 168.519 1.00 90.31  ? 73  C   X "C3'" 1 
ATOM   1351 O  "O3'" . C   A 1 376 ? 169.449 165.746 168.530 1.00 90.31  ? 73  C   X "O3'" 1 
ATOM   1352 C  "C2'" . C   A 1 376 ? 171.076 164.227 169.534 1.00 90.31  ? 73  C   X "C2'" 1 
ATOM   1353 O  "O2'" . C   A 1 376 ? 170.714 164.804 170.777 1.00 90.31  ? 73  C   X "O2'" 1 
ATOM   1354 C  "C1'" . C   A 1 376 ? 171.048 162.714 169.693 1.00 90.31  ? 73  C   X "C1'" 1 
ATOM   1355 N  N1    . C   A 1 376 ? 171.994 162.029 168.791 1.00 90.31  ? 73  C   X N1    1 
ATOM   1356 C  C2    . C   A 1 376 ? 173.363 162.139 168.995 1.00 90.31  ? 73  C   X C2    1 
ATOM   1357 O  O2    . C   A 1 376 ? 173.761 162.835 169.930 1.00 90.31  ? 73  C   X O2    1 
ATOM   1358 N  N3    . C   A 1 376 ? 174.209 161.503 168.167 1.00 90.31  ? 73  C   X N3    1 
ATOM   1359 C  C4    . C   A 1 376 ? 173.737 160.753 167.184 1.00 90.31  ? 73  C   X C4    1 
ATOM   1360 N  N4    . C   A 1 376 ? 174.603 160.130 166.391 1.00 90.31  ? 73  C   X N4    1 
ATOM   1361 C  C5    . C   A 1 376 ? 172.351 160.619 166.958 1.00 90.31  ? 73  C   X C5    1 
ATOM   1362 C  C6    . C   A 1 376 ? 171.525 161.264 167.777 1.00 90.31  ? 73  C   X C6    1 
ATOM   1363 P  P     . C   A 1 377 ? 170.072 166.865 167.574 1.00 91.92  ? 74  C   X P     1 
ATOM   1364 O  OP1   . C   A 1 377 ? 169.259 168.091 167.716 1.00 91.92  ? 74  C   X OP1   1 
ATOM   1365 O  OP2   . C   A 1 377 ? 170.278 166.261 166.242 1.00 91.92  ? 74  C   X OP2   1 
ATOM   1366 O  "O5'" . C   A 1 377 ? 171.509 167.133 168.189 1.00 91.92  ? 74  C   X "O5'" 1 
ATOM   1367 C  "C5'" . C   A 1 377 ? 171.662 167.699 169.479 1.00 91.92  ? 74  C   X "C5'" 1 
ATOM   1368 C  "C4'" . C   A 1 377 ? 173.113 167.947 169.774 1.00 91.92  ? 74  C   X "C4'" 1 
ATOM   1369 O  "O4'" . C   A 1 377 ? 173.797 166.681 169.937 1.00 91.92  ? 74  C   X "O4'" 1 
ATOM   1370 C  "C3'" . C   A 1 377 ? 173.878 168.638 168.665 1.00 91.92  ? 74  C   X "C3'" 1 
ATOM   1371 O  "O3'" . C   A 1 377 ? 173.697 170.040 168.673 1.00 91.92  ? 74  C   X "O3'" 1 
ATOM   1372 C  "C2'" . C   A 1 377 ? 175.309 168.195 168.920 1.00 91.92  ? 74  C   X "C2'" 1 
ATOM   1373 O  "O2'" . C   A 1 377 ? 175.882 168.949 169.976 1.00 91.92  ? 74  C   X "O2'" 1 
ATOM   1374 C  "C1'" . C   A 1 377 ? 175.100 166.764 169.410 1.00 91.92  ? 74  C   X "C1'" 1 
ATOM   1375 N  N1    . C   A 1 377 ? 175.235 165.766 168.326 1.00 91.92  ? 74  C   X N1    1 
ATOM   1376 C  C2    . C   A 1 377 ? 176.503 165.304 167.999 1.00 91.92  ? 74  C   X C2    1 
ATOM   1377 O  O2    . C   A 1 377 ? 177.460 165.751 168.636 1.00 91.92  ? 74  C   X O2    1 
ATOM   1378 N  N3    . C   A 1 377 ? 176.663 164.385 167.023 1.00 91.92  ? 74  C   X N3    1 
ATOM   1379 C  C4    . C   A 1 377 ? 175.599 163.935 166.374 1.00 91.92  ? 74  C   X C4    1 
ATOM   1380 N  N4    . C   A 1 377 ? 175.786 163.034 165.417 1.00 91.92  ? 74  C   X N4    1 
ATOM   1381 C  C5    . C   A 1 377 ? 174.292 164.384 166.680 1.00 91.92  ? 74  C   X C5    1 
ATOM   1382 C  C6    . C   A 1 377 ? 174.153 165.288 167.653 1.00 91.92  ? 74  C   X C6    1 
ATOM   1383 P  P     . A   A 1 378 ? 173.532 170.835 167.291 1.00 92.84  ? 75  A   X P     1 
ATOM   1384 O  OP1   . A   A 1 378 ? 173.041 172.198 167.594 1.00 92.84  ? 75  A   X OP1   1 
ATOM   1385 O  OP2   . A   A 1 378 ? 172.759 169.993 166.355 1.00 92.84  ? 75  A   X OP2   1 
ATOM   1386 O  "O5'" . A   A 1 378 ? 175.020 170.938 166.742 1.00 92.84  ? 75  A   X "O5'" 1 
ATOM   1387 C  "C5'" . A   A 1 378 ? 176.044 171.480 167.556 1.00 92.84  ? 75  A   X "C5'" 1 
ATOM   1388 C  "C4'" . A   A 1 378 ? 177.422 171.254 166.986 1.00 92.84  ? 75  A   X "C4'" 1 
ATOM   1389 O  "O4'" . A   A 1 378 ? 177.948 169.963 167.405 1.00 92.84  ? 75  A   X "O4'" 1 
ATOM   1390 C  "C3'" . A   A 1 378 ? 177.561 171.193 165.480 1.00 92.84  ? 75  A   X "C3'" 1 
ATOM   1391 O  "O3'" . A   A 1 378 ? 177.331 172.416 164.787 1.00 92.84  ? 75  A   X "O3'" 1 
ATOM   1392 C  "C2'" . A   A 1 378 ? 178.933 170.556 165.348 1.00 92.84  ? 75  A   X "C2'" 1 
ATOM   1393 O  "O2'" . A   A 1 378 ? 179.942 171.439 165.807 1.00 92.84  ? 75  A   X "O2'" 1 
ATOM   1394 C  "C1'" . A   A 1 378 ? 178.812 169.462 166.399 1.00 92.84  ? 75  A   X "C1'" 1 
ATOM   1395 N  N9    . A   A 1 378 ? 178.209 168.259 165.801 1.00 92.84  ? 75  A   X N9    1 
ATOM   1396 C  C8    . A   A 1 378 ? 176.933 167.802 165.921 1.00 92.84  ? 75  A   X C8    1 
ATOM   1397 N  N7    . A   A 1 378 ? 176.691 166.719 165.239 1.00 92.84  ? 75  A   X N7    1 
ATOM   1398 C  C5    . A   A 1 378 ? 177.889 166.456 164.616 1.00 92.84  ? 75  A   X C5    1 
ATOM   1399 C  C6    . A   A 1 378 ? 178.284 165.448 163.740 1.00 92.84  ? 75  A   X C6    1 
ATOM   1400 N  N6    . A   A 1 378 ? 177.478 164.472 163.346 1.00 92.84  ? 75  A   X N6    1 
ATOM   1401 N  N1    . A   A 1 378 ? 179.546 165.450 163.288 1.00 92.84  ? 75  A   X N1    1 
ATOM   1402 C  C2    . A   A 1 378 ? 180.344 166.433 163.698 1.00 92.84  ? 75  A   X C2    1 
ATOM   1403 N  N3    . A   A 1 378 ? 180.087 167.444 164.511 1.00 92.84  ? 75  A   X N3    1 
ATOM   1404 C  C4    . A   A 1 378 ? 178.826 167.397 164.943 1.00 92.84  ? 75  A   X C4    1 
ATOM   1405 P  P     . G   A 1 379 ? 178.496 173.456 164.416 1.00 94.73  ? 76  G   X P     1 
ATOM   1406 O  OP1   . G   A 1 379 ? 179.327 173.671 165.623 1.00 94.73  ? 76  G   X OP1   1 
ATOM   1407 O  OP2   . G   A 1 379 ? 177.834 174.607 163.761 1.00 94.73  ? 76  G   X OP2   1 
ATOM   1408 O  "O5'" . G   A 1 379 ? 179.393 172.721 163.325 1.00 94.73  ? 76  G   X "O5'" 1 
ATOM   1409 C  "C5'" . G   A 1 379 ? 180.776 173.032 163.219 1.00 94.73  ? 76  G   X "C5'" 1 
ATOM   1410 C  "C4'" . G   A 1 379 ? 181.505 172.103 162.286 1.00 94.73  ? 76  G   X "C4'" 1 
ATOM   1411 O  "O4'" . G   A 1 379 ? 181.202 170.735 162.614 1.00 94.73  ? 76  G   X "O4'" 1 
ATOM   1412 C  "C3'" . G   A 1 379 ? 181.152 172.224 160.819 1.00 94.73  ? 76  G   X "C3'" 1 
ATOM   1413 O  "O3'" . G   A 1 379 ? 181.885 173.257 160.201 1.00 94.73  ? 76  G   X "O3'" 1 
ATOM   1414 C  "C2'" . G   A 1 379 ? 181.504 170.855 160.263 1.00 94.73  ? 76  G   X "C2'" 1 
ATOM   1415 O  "O2'" . G   A 1 379 ? 182.877 170.800 159.914 1.00 94.73  ? 76  G   X "O2'" 1 
ATOM   1416 C  "C1'" . G   A 1 379 ? 181.270 169.942 161.460 1.00 94.73  ? 76  G   X "C1'" 1 
ATOM   1417 N  N9    . G   A 1 379 ? 180.048 169.132 161.369 1.00 94.73  ? 76  G   X N9    1 
ATOM   1418 C  C8    . G   A 1 379 ? 178.870 169.337 162.017 1.00 94.73  ? 76  G   X C8    1 
ATOM   1419 N  N7    . G   A 1 379 ? 177.983 168.420 161.763 1.00 94.73  ? 76  G   X N7    1 
ATOM   1420 C  C5    . G   A 1 379 ? 178.624 167.554 160.903 1.00 94.73  ? 76  G   X C5    1 
ATOM   1421 C  C6    . G   A 1 379 ? 178.173 166.368 160.280 1.00 94.73  ? 76  G   X C6    1 
ATOM   1422 O  O6    . G   A 1 379 ? 177.072 165.823 160.373 1.00 94.73  ? 76  G   X O6    1 
ATOM   1423 N  N1    . G   A 1 379 ? 179.153 165.794 159.478 1.00 94.73  ? 76  G   X N1    1 
ATOM   1424 C  C2    . G   A 1 379 ? 180.406 166.304 159.298 1.00 94.73  ? 76  G   X C2    1 
ATOM   1425 N  N2    . G   A 1 379 ? 181.229 165.626 158.495 1.00 94.73  ? 76  G   X N2    1 
ATOM   1426 N  N3    . G   A 1 379 ? 180.836 167.408 159.874 1.00 94.73  ? 76  G   X N3    1 
ATOM   1427 C  C4    . G   A 1 379 ? 179.902 167.977 160.657 1.00 94.73  ? 76  G   X C4    1 
ATOM   1428 P  P     . C   A 1 380 ? 181.252 174.084 158.991 1.00 93.72  ? 77  C   X P     1 
ATOM   1429 O  OP1   . C   A 1 380 ? 182.269 175.068 158.559 1.00 93.72  ? 77  C   X OP1   1 
ATOM   1430 O  OP2   . C   A 1 380 ? 179.921 174.557 159.431 1.00 93.72  ? 77  C   X OP2   1 
ATOM   1431 O  "O5'" . C   A 1 380 ? 181.083 173.002 157.838 1.00 93.72  ? 77  C   X "O5'" 1 
ATOM   1432 C  "C5'" . C   A 1 380 ? 182.213 172.495 157.145 1.00 93.72  ? 77  C   X "C5'" 1 
ATOM   1433 C  "C4'" . C   A 1 380 ? 181.881 171.241 156.377 1.00 93.72  ? 77  C   X "C4'" 1 
ATOM   1434 O  "O4'" . C   A 1 380 ? 181.362 170.243 157.287 1.00 93.72  ? 77  C   X "O4'" 1 
ATOM   1435 C  "C3'" . C   A 1 380 ? 180.807 171.371 155.311 1.00 93.72  ? 77  C   X "C3'" 1 
ATOM   1436 O  "O3'" . C   A 1 380 ? 181.315 171.869 154.090 1.00 93.72  ? 77  C   X "O3'" 1 
ATOM   1437 C  "C2'" . C   A 1 380 ? 180.275 169.951 155.198 1.00 93.72  ? 77  C   X "C2'" 1 
ATOM   1438 O  "O2'" . C   A 1 380 ? 181.126 169.164 154.383 1.00 93.72  ? 77  C   X "O2'" 1 
ATOM   1439 C  "C1'" . C   A 1 380 ? 180.388 169.460 156.642 1.00 93.72  ? 77  C   X "C1'" 1 
ATOM   1440 N  N1    . C   A 1 380 ? 179.110 169.583 157.377 1.00 93.72  ? 77  C   X N1    1 
ATOM   1441 C  C2    . C   A 1 380 ? 178.313 168.455 157.468 1.00 93.72  ? 77  C   X C2    1 
ATOM   1442 O  O2    . C   A 1 380 ? 178.723 167.416 156.948 1.00 93.72  ? 77  C   X O2    1 
ATOM   1443 N  N3    . C   A 1 380 ? 177.137 168.514 158.118 1.00 93.72  ? 77  C   X N3    1 
ATOM   1444 C  C4    . C   A 1 380 ? 176.746 169.657 158.663 1.00 93.72  ? 77  C   X C4    1 
ATOM   1445 N  N4    . C   A 1 380 ? 175.577 169.677 159.295 1.00 93.72  ? 77  C   X N4    1 
ATOM   1446 C  C5    . C   A 1 380 ? 177.532 170.832 158.585 1.00 93.72  ? 77  C   X C5    1 
ATOM   1447 C  C6    . C   A 1 380 ? 178.694 170.749 157.941 1.00 93.72  ? 77  C   X C6    1 
ATOM   1448 P  P     . G   A 1 381 ? 180.546 173.030 153.295 1.00 94.40  ? 78  G   X P     1 
ATOM   1449 O  OP1   . G   A 1 381 ? 179.204 172.561 152.904 1.00 94.40  ? 78  G   X OP1   1 
ATOM   1450 O  OP2   . G   A 1 381 ? 181.471 173.556 152.270 1.00 94.40  ? 78  G   X OP2   1 
ATOM   1451 O  "O5'" . G   A 1 381 ? 180.319 174.163 154.379 1.00 94.40  ? 78  G   X "O5'" 1 
ATOM   1452 C  "C5'" . G   A 1 381 ? 179.686 175.383 154.022 1.00 94.40  ? 78  G   X "C5'" 1 
ATOM   1453 C  "C4'" . G   A 1 381 ? 178.582 175.747 154.983 1.00 94.40  ? 78  G   X "C4'" 1 
ATOM   1454 O  "O4'" . G   A 1 381 ? 177.463 174.843 154.793 1.00 94.40  ? 78  G   X "O4'" 1 
ATOM   1455 C  "C3'" . G   A 1 381 ? 178.946 175.674 156.464 1.00 94.40  ? 78  G   X "C3'" 1 
ATOM   1456 O  "O3'" . G   A 1 381 ? 178.286 176.709 157.175 1.00 94.40  ? 78  G   X "O3'" 1 
ATOM   1457 C  "C2'" . G   A 1 381 ? 178.355 174.345 156.896 1.00 94.40  ? 78  G   X "C2'" 1 
ATOM   1458 O  "O2'" . G   A 1 381 ? 178.034 174.285 158.264 1.00 94.40  ? 78  G   X "O2'" 1 
ATOM   1459 C  "C1'" . G   A 1 381 ? 177.112 174.255 156.025 1.00 94.40  ? 78  G   X "C1'" 1 
ATOM   1460 N  N9    . G   A 1 381 ? 176.693 172.880 155.771 1.00 94.40  ? 78  G   X N9    1 
ATOM   1461 C  C8    . G   A 1 381 ? 177.388 171.926 155.080 1.00 94.40  ? 78  G   X C8    1 
ATOM   1462 N  N7    . G   A 1 381 ? 176.774 170.785 155.025 1.00 94.40  ? 78  G   X N7    1 
ATOM   1463 C  C5    . G   A 1 381 ? 175.604 171.006 155.724 1.00 94.40  ? 78  G   X C5    1 
ATOM   1464 C  C6    . G   A 1 381 ? 174.536 170.134 156.002 1.00 94.40  ? 78  G   X C6    1 
ATOM   1465 O  O6    . G   A 1 381 ? 174.401 168.955 155.676 1.00 94.40  ? 78  G   X O6    1 
ATOM   1466 N  N1    . G   A 1 381 ? 173.551 170.759 156.739 1.00 94.40  ? 78  G   X N1    1 
ATOM   1467 C  C2    . G   A 1 381 ? 173.587 172.058 157.157 1.00 94.40  ? 78  G   X C2    1 
ATOM   1468 N  N2    . G   A 1 381 ? 172.532 172.477 157.862 1.00 94.40  ? 78  G   X N2    1 
ATOM   1469 N  N3    . G   A 1 381 ? 174.578 172.884 156.908 1.00 94.40  ? 78  G   X N3    1 
ATOM   1470 C  C4    . G   A 1 381 ? 175.541 172.291 156.191 1.00 94.40  ? 78  G   X C4    1 
ATOM   1471 P  P     . U   A 1 382 ? 179.035 178.099 157.445 1.00 99.09  ? 79  U   X P     1 
ATOM   1472 O  OP1   . U   A 1 382 ? 180.473 177.912 157.147 1.00 99.09  ? 79  U   X OP1   1 
ATOM   1473 O  OP2   . U   A 1 382 ? 178.621 178.606 158.775 1.00 99.09  ? 79  U   X OP2   1 
ATOM   1474 O  "O5'" . U   A 1 382 ? 178.421 179.054 156.337 1.00 99.09  ? 79  U   X "O5'" 1 
ATOM   1475 C  "C5'" . U   A 1 382 ? 177.091 178.854 155.878 1.00 99.09  ? 79  U   X "C5'" 1 
ATOM   1476 C  "C4'" . U   A 1 382 ? 176.800 179.697 154.669 1.00 99.09  ? 79  U   X "C4'" 1 
ATOM   1477 O  "O4'" . U   A 1 382 ? 177.192 181.060 154.966 1.00 99.09  ? 79  U   X "O4'" 1 
ATOM   1478 C  "C3'" . U   A 1 382 ? 177.565 179.301 153.416 1.00 99.09  ? 79  U   X "C3'" 1 
ATOM   1479 O  "O3'" . U   A 1 382 ? 176.794 179.645 152.267 1.00 99.09  ? 79  U   X "O3'" 1 
ATOM   1480 C  "C2'" . U   A 1 382 ? 178.796 180.194 153.482 1.00 99.09  ? 79  U   X "C2'" 1 
ATOM   1481 O  "O2'" . U   A 1 382 ? 179.405 180.437 152.232 1.00 99.09  ? 79  U   X "O2'" 1 
ATOM   1482 C  "C1'" . U   A 1 382 ? 178.218 181.472 154.086 1.00 99.09  ? 79  U   X "C1'" 1 
ATOM   1483 N  N1    . U   A 1 382 ? 179.186 182.237 154.878 1.00 99.09  ? 79  U   X N1    1 
ATOM   1484 C  C2    . U   A 1 382 ? 178.989 183.597 154.971 1.00 99.09  ? 79  U   X C2    1 
ATOM   1485 O  O2    . U   A 1 382 ? 178.058 184.168 154.433 1.00 99.09  ? 79  U   X O2    1 
ATOM   1486 N  N3    . U   A 1 382 ? 179.919 184.256 155.727 1.00 99.09  ? 79  U   X N3    1 
ATOM   1487 C  C4    . U   A 1 382 ? 181.003 183.703 156.374 1.00 99.09  ? 79  U   X C4    1 
ATOM   1488 O  O4    . U   A 1 382 ? 181.756 184.437 157.012 1.00 99.09  ? 79  U   X O4    1 
ATOM   1489 C  C5    . U   A 1 382 ? 181.139 182.288 156.223 1.00 99.09  ? 79  U   X C5    1 
ATOM   1490 C  C6    . U   A 1 382 ? 180.244 181.618 155.497 1.00 99.09  ? 79  U   X C6    1 
ATOM   1491 P  P     . A   A 1 383 ? 175.852 178.555 151.563 1.00 94.03  ? 80  A   X P     1 
ATOM   1492 O  OP1   . A   A 1 383 ? 175.331 179.173 150.327 1.00 94.03  ? 80  A   X OP1   1 
ATOM   1493 O  OP2   . A   A 1 383 ? 174.911 178.012 152.568 1.00 94.03  ? 80  A   X OP2   1 
ATOM   1494 O  "O5'" . A   A 1 383 ? 176.846 177.383 151.153 1.00 94.03  ? 80  A   X "O5'" 1 
ATOM   1495 C  "C5'" . A   A 1 383 ? 177.892 177.607 150.222 1.00 94.03  ? 80  A   X "C5'" 1 
ATOM   1496 C  "C4'" . A   A 1 383 ? 178.212 176.357 149.448 1.00 94.03  ? 80  A   X "C4'" 1 
ATOM   1497 O  "O4'" . A   A 1 383 ? 178.405 175.254 150.365 1.00 94.03  ? 80  A   X "O4'" 1 
ATOM   1498 C  "C3'" . A   A 1 383 ? 177.124 175.873 148.507 1.00 94.03  ? 80  A   X "C3'" 1 
ATOM   1499 O  "O3'" . A   A 1 383 ? 177.150 176.552 147.267 1.00 94.03  ? 80  A   X "O3'" 1 
ATOM   1500 C  "C2'" . A   A 1 383 ? 177.417 174.385 148.391 1.00 94.03  ? 80  A   X "C2'" 1 
ATOM   1501 O  "O2'" . A   A 1 383 ? 178.480 174.149 147.485 1.00 94.03  ? 80  A   X "O2'" 1 
ATOM   1502 C  "C1'" . A   A 1 383 ? 177.911 174.063 149.799 1.00 94.03  ? 80  A   X "C1'" 1 
ATOM   1503 N  N9    . A   A 1 383 ? 176.840 173.554 150.671 1.00 94.03  ? 80  A   X N9    1 
ATOM   1504 C  C8    . A   A 1 383 ? 176.380 174.136 151.819 1.00 94.03  ? 80  A   X C8    1 
ATOM   1505 N  N7    . A   A 1 383 ? 175.429 173.463 152.408 1.00 94.03  ? 80  A   X N7    1 
ATOM   1506 C  C5    . A   A 1 383 ? 175.264 172.366 151.589 1.00 94.03  ? 80  A   X C5    1 
ATOM   1507 C  C6    . A   A 1 383 ? 174.404 171.278 151.671 1.00 94.03  ? 80  A   X C6    1 
ATOM   1508 N  N6    . A   A 1 383 ? 173.529 171.127 152.653 1.00 94.03  ? 80  A   X N6    1 
ATOM   1509 N  N1    . A   A 1 383 ? 174.469 170.343 150.714 1.00 94.03  ? 80  A   X N1    1 
ATOM   1510 C  C2    . A   A 1 383 ? 175.356 170.514 149.733 1.00 94.03  ? 80  A   X C2    1 
ATOM   1511 N  N3    . A   A 1 383 ? 176.227 171.500 149.543 1.00 94.03  ? 80  A   X N3    1 
ATOM   1512 C  C4    . A   A 1 383 ? 176.125 172.402 150.521 1.00 94.03  ? 80  A   X C4    1 
ATOM   1513 P  P     . G   A 1 384 ? 175.791 177.005 146.548 1.00 91.89  ? 81  G   X P     1 
ATOM   1514 O  OP1   . G   A 1 384 ? 176.150 177.946 145.462 1.00 91.89  ? 81  G   X OP1   1 
ATOM   1515 O  OP2   . G   A 1 384 ? 174.809 177.423 147.572 1.00 91.89  ? 81  G   X OP2   1 
ATOM   1516 O  "O5'" . G   A 1 384 ? 175.281 175.674 145.852 1.00 91.89  ? 81  G   X "O5'" 1 
ATOM   1517 C  "C5'" . G   A 1 384 ? 176.095 174.997 144.910 1.00 91.89  ? 81  G   X "C5'" 1 
ATOM   1518 C  "C4'" . G   A 1 384 ? 175.490 173.678 144.516 1.00 91.89  ? 81  G   X "C4'" 1 
ATOM   1519 O  "O4'" . G   A 1 384 ? 175.524 172.765 145.638 1.00 91.89  ? 81  G   X "O4'" 1 
ATOM   1520 C  "C3'" . G   A 1 384 ? 174.031 173.724 144.110 1.00 91.89  ? 81  G   X "C3'" 1 
ATOM   1521 O  "O3'" . G   A 1 384 ? 173.886 174.103 142.754 1.00 91.89  ? 81  G   X "O3'" 1 
ATOM   1522 C  "C2'" . G   A 1 384 ? 173.553 172.308 144.404 1.00 91.89  ? 81  G   X "C2'" 1 
ATOM   1523 O  "O2'" . G   A 1 384 ? 173.928 171.419 143.362 1.00 91.89  ? 81  G   X "O2'" 1 
ATOM   1524 C  "C1'" . G   A 1 384 ? 174.371 171.959 145.642 1.00 91.89  ? 81  G   X "C1'" 1 
ATOM   1525 N  N9    . G   A 1 384 ? 173.653 172.230 146.890 1.00 91.89  ? 81  G   X N9    1 
ATOM   1526 C  C8    . G   A 1 384 ? 173.882 173.309 147.685 1.00 91.89  ? 81  G   X C8    1 
ATOM   1527 N  N7    . G   A 1 384 ? 173.139 173.324 148.744 1.00 91.89  ? 81  G   X N7    1 
ATOM   1528 C  C5    . G   A 1 384 ? 172.390 172.176 148.638 1.00 91.89  ? 81  G   X C5    1 
ATOM   1529 C  C6    . G   A 1 384 ? 171.410 171.675 149.504 1.00 91.89  ? 81  G   X C6    1 
ATOM   1530 O  O6    . G   A 1 384 ? 171.014 172.167 150.559 1.00 91.89  ? 81  G   X O6    1 
ATOM   1531 N  N1    . G   A 1 384 ? 170.878 170.491 149.040 1.00 91.89  ? 81  G   X N1    1 
ATOM   1532 C  C2    . G   A 1 384 ? 171.243 169.861 147.888 1.00 91.89  ? 81  G   X C2    1 
ATOM   1533 N  N2    . G   A 1 384 ? 170.613 168.719 147.610 1.00 91.89  ? 81  G   X N2    1 
ATOM   1534 N  N3    . G   A 1 384 ? 172.163 170.322 147.065 1.00 91.89  ? 81  G   X N3    1 
ATOM   1535 C  C4    . G   A 1 384 ? 172.689 171.480 147.502 1.00 91.89  ? 81  G   X C4    1 
ATOM   1536 P  P     . G   A 1 385 ? 172.486 174.642 142.194 1.00 91.11  ? 82  G   X P     1 
ATOM   1537 O  OP1   . G   A 1 385 ? 172.019 173.657 141.192 1.00 91.11  ? 82  G   X OP1   1 
ATOM   1538 O  OP2   . G   A 1 385 ? 172.630 176.065 141.821 1.00 91.11  ? 82  G   X OP2   1 
ATOM   1539 O  "O5'" . G   A 1 385 ? 171.523 174.598 143.452 1.00 91.11  ? 82  G   X "O5'" 1 
ATOM   1540 C  "C5'" . G   A 1 385 ? 170.119 174.546 143.281 1.00 91.11  ? 82  G   X "C5'" 1 
ATOM   1541 C  "C4'" . G   A 1 385 ? 169.589 173.200 143.686 1.00 91.11  ? 82  G   X "C4'" 1 
ATOM   1542 O  "O4'" . G   A 1 385 ? 170.270 172.769 144.881 1.00 91.11  ? 82  G   X "O4'" 1 
ATOM   1543 C  "C3'" . G   A 1 385 ? 168.122 173.150 144.054 1.00 91.11  ? 82  G   X "C3'" 1 
ATOM   1544 O  "O3'" . G   A 1 385 ? 167.298 172.995 142.925 1.00 91.11  ? 82  G   X "O3'" 1 
ATOM   1545 C  "C2'" . G   A 1 385 ? 168.048 171.967 144.999 1.00 91.11  ? 82  G   X "C2'" 1 
ATOM   1546 O  "O2'" . G   A 1 385 ? 168.026 170.755 144.266 1.00 91.11  ? 82  G   X "O2'" 1 
ATOM   1547 C  "C1'" . G   A 1 385 ? 169.388 172.058 145.710 1.00 91.11  ? 82  G   X "C1'" 1 
ATOM   1548 N  N9    . G   A 1 385 ? 169.322 172.741 147.011 1.00 91.11  ? 82  G   X N9    1 
ATOM   1549 C  C8    . G   A 1 385 ? 170.130 173.764 147.417 1.00 91.11  ? 82  G   X C8    1 
ATOM   1550 N  N7    . G   A 1 385 ? 169.891 174.162 148.628 1.00 91.11  ? 82  G   X N7    1 
ATOM   1551 C  C5    . G   A 1 385 ? 168.854 173.348 149.041 1.00 91.11  ? 82  G   X C5    1 
ATOM   1552 C  C6    . G   A 1 385 ? 168.179 173.308 150.272 1.00 91.11  ? 82  G   X C6    1 
ATOM   1553 O  O6    . G   A 1 385 ? 168.348 174.020 151.264 1.00 91.11  ? 82  G   X O6    1 
ATOM   1554 N  N1    . G   A 1 385 ? 167.205 172.328 150.269 1.00 91.11  ? 82  G   X N1    1 
ATOM   1555 C  C2    . G   A 1 385 ? 166.935 171.485 149.232 1.00 91.11  ? 82  G   X C2    1 
ATOM   1556 N  N2    . G   A 1 385 ? 165.958 170.600 149.410 1.00 91.11  ? 82  G   X N2    1 
ATOM   1557 N  N3    . G   A 1 385 ? 167.560 171.510 148.086 1.00 91.11  ? 82  G   X N3    1 
ATOM   1558 C  C4    . G   A 1 385 ? 168.504 172.456 148.063 1.00 91.11  ? 82  G   X C4    1 
ATOM   1559 P  P     . G   A 1 386 ? 166.147 174.060 142.644 1.00 90.99  ? 83  G   X P     1 
ATOM   1560 O  OP1   . G   A 1 386 ? 165.435 173.623 141.421 1.00 90.99  ? 83  G   X OP1   1 
ATOM   1561 O  OP2   . G   A 1 386 ? 166.762 175.406 142.718 1.00 90.99  ? 83  G   X OP2   1 
ATOM   1562 O  "O5'" . G   A 1 386 ? 165.178 173.897 143.895 1.00 90.99  ? 83  G   X "O5'" 1 
ATOM   1563 C  "C5'" . G   A 1 386 ? 164.562 172.655 144.188 1.00 90.99  ? 83  G   X "C5'" 1 
ATOM   1564 C  "C4'" . G   A 1 386 ? 163.956 172.656 145.568 1.00 90.99  ? 83  G   X "C4'" 1 
ATOM   1565 O  "O4'" . G   A 1 386 ? 165.001 172.590 146.564 1.00 90.99  ? 83  G   X "O4'" 1 
ATOM   1566 C  "C3'" . G   A 1 386 ? 163.171 173.894 145.948 1.00 90.99  ? 83  G   X "C3'" 1 
ATOM   1567 O  "O3'" . G   A 1 386 ? 161.859 173.879 145.435 1.00 90.99  ? 83  G   X "O3'" 1 
ATOM   1568 C  "C2'" . G   A 1 386 ? 163.216 173.859 147.465 1.00 90.99  ? 83  G   X "C2'" 1 
ATOM   1569 O  "O2'" . G   A 1 386 ? 162.272 172.928 147.963 1.00 90.99  ? 83  G   X "O2'" 1 
ATOM   1570 C  "C1'" . G   A 1 386 ? 164.611 173.302 147.713 1.00 90.99  ? 83  G   X "C1'" 1 
ATOM   1571 N  N9    . G   A 1 386 ? 165.583 174.370 147.954 1.00 90.99  ? 83  G   X N9    1 
ATOM   1572 C  C8    . G   A 1 386 ? 166.409 174.961 147.051 1.00 90.99  ? 83  G   X C8    1 
ATOM   1573 N  N7    . G   A 1 386 ? 167.146 175.886 147.585 1.00 90.99  ? 83  G   X N7    1 
ATOM   1574 C  C5    . G   A 1 386 ? 166.774 175.900 148.915 1.00 90.99  ? 83  G   X C5    1 
ATOM   1575 C  C6    . G   A 1 386 ? 167.226 176.688 149.994 1.00 90.99  ? 83  G   X C6    1 
ATOM   1576 O  O6    . G   A 1 386 ? 168.079 177.575 150.003 1.00 90.99  ? 83  G   X O6    1 
ATOM   1577 N  N1    . G   A 1 386 ? 166.578 176.367 151.167 1.00 90.99  ? 83  G   X N1    1 
ATOM   1578 C  C2    . G   A 1 386 ? 165.620 175.411 151.287 1.00 90.99  ? 83  G   X C2    1 
ATOM   1579 N  N2    . G   A 1 386 ? 165.119 175.252 152.508 1.00 90.99  ? 83  G   X N2    1 
ATOM   1580 N  N3    . G   A 1 386 ? 165.187 174.665 150.300 1.00 90.99  ? 83  G   X N3    1 
ATOM   1581 C  C4    . G   A 1 386 ? 165.804 174.971 149.151 1.00 90.99  ? 83  G   X C4    1 
ATOM   1582 P  P     . A   A 1 387 ? 161.535 174.556 144.025 1.00 87.58  ? 84  A   X P     1 
ATOM   1583 O  OP1   . A   A 1 387 ? 161.745 173.544 142.971 1.00 87.58  ? 84  A   X OP1   1 
ATOM   1584 O  OP2   . A   A 1 387 ? 162.229 175.859 143.962 1.00 87.58  ? 84  A   X OP2   1 
ATOM   1585 O  "O5'" . A   A 1 387 ? 159.977 174.822 144.101 1.00 87.58  ? 84  A   X "O5'" 1 
ATOM   1586 C  "C5'" . A   A 1 387 ? 159.088 173.772 144.440 1.00 87.58  ? 84  A   X "C5'" 1 
ATOM   1587 C  "C4'" . A   A 1 387 ? 157.939 174.295 145.250 1.00 87.58  ? 84  A   X "C4'" 1 
ATOM   1588 O  "O4'" . A   A 1 387 ? 158.134 173.981 146.647 1.00 87.58  ? 84  A   X "O4'" 1 
ATOM   1589 C  "C3'" . A   A 1 387 ? 157.774 175.800 145.214 1.00 87.58  ? 84  A   X "C3'" 1 
ATOM   1590 O  "O3'" . A   A 1 387 ? 157.078 176.196 144.044 1.00 87.58  ? 84  A   X "O3'" 1 
ATOM   1591 C  "C2'" . A   A 1 387 ? 157.075 176.096 146.531 1.00 87.58  ? 84  A   X "C2'" 1 
ATOM   1592 O  "O2'" . A   A 1 387 ? 155.690 175.826 146.425 1.00 87.58  ? 84  A   X "O2'" 1 
ATOM   1593 C  "C1'" . A   A 1 387 ? 157.690 175.043 147.450 1.00 87.58  ? 84  A   X "C1'" 1 
ATOM   1594 N  N9    . A   A 1 387 ? 158.857 175.522 148.203 1.00 87.58  ? 84  A   X N9    1 
ATOM   1595 C  C8    . A   A 1 387 ? 160.013 176.007 147.679 1.00 87.58  ? 84  A   X C8    1 
ATOM   1596 N  N7    . A   A 1 387 ? 160.901 176.315 148.576 1.00 87.58  ? 84  A   X N7    1 
ATOM   1597 C  C5    . A   A 1 387 ? 160.305 175.987 149.771 1.00 87.58  ? 84  A   X C5    1 
ATOM   1598 C  C6    . A   A 1 387 ? 160.746 176.080 151.089 1.00 87.58  ? 84  A   X C6    1 
ATOM   1599 N  N6    . A   A 1 387 ? 161.937 176.553 151.430 1.00 87.58  ? 84  A   X N6    1 
ATOM   1600 N  N1    . A   A 1 387 ? 159.921 175.674 152.059 1.00 87.58  ? 84  A   X N1    1 
ATOM   1601 C  C2    . A   A 1 387 ? 158.730 175.204 151.705 1.00 87.58  ? 84  A   X C2    1 
ATOM   1602 N  N3    . A   A 1 387 ? 158.202 175.069 150.501 1.00 87.58  ? 84  A   X N3    1 
ATOM   1603 C  C4    . A   A 1 387 ? 159.051 175.481 149.560 1.00 87.58  ? 84  A   X C4    1 
ATOM   1604 P  P     . A   A 1 388 ? 156.208 177.540 143.950 1.00 91.44  ? 85  A   X P     1 
ATOM   1605 O  OP1   . A   A 1 388 ? 154.973 177.367 144.748 1.00 91.44  ? 85  A   X OP1   1 
ATOM   1606 O  OP2   . A   A 1 388 ? 156.083 177.849 142.507 1.00 91.44  ? 85  A   X OP2   1 
ATOM   1607 O  "O5'" . A   A 1 388 ? 157.112 178.663 144.613 1.00 91.44  ? 85  A   X "O5'" 1 
ATOM   1608 C  "C5'" . A   A 1 388 ? 156.603 179.452 145.678 1.00 91.44  ? 85  A   X "C5'" 1 
ATOM   1609 C  "C4'" . A   A 1 388 ? 155.540 180.407 145.207 1.00 91.44  ? 85  A   X "C4'" 1 
ATOM   1610 O  "O4'" . A   A 1 388 ? 154.490 180.492 146.211 1.00 91.44  ? 85  A   X "O4'" 1 
ATOM   1611 C  "C3'" . A   A 1 388 ? 156.014 181.835 144.989 1.00 91.44  ? 85  A   X "C3'" 1 
ATOM   1612 O  "O3'" . A   A 1 388 ? 155.153 182.434 144.029 1.00 91.44  ? 85  A   X "O3'" 1 
ATOM   1613 C  "C2'" . A   A 1 388 ? 155.735 182.458 146.343 1.00 91.44  ? 85  A   X "C2'" 1 
ATOM   1614 O  "O2'" . A   A 1 388 ? 155.690 183.865 146.346 1.00 91.44  ? 85  A   X "O2'" 1 
ATOM   1615 C  "C1'" . A   A 1 388 ? 154.387 181.827 146.659 1.00 91.44  ? 85  A   X "C1'" 1 
ATOM   1616 N  N9    . A   A 1 388 ? 154.022 181.825 148.072 1.00 91.44  ? 85  A   X N9    1 
ATOM   1617 C  C8    . A   A 1 388 ? 154.814 181.994 149.167 1.00 91.44  ? 85  A   X C8    1 
ATOM   1618 N  N7    . A   A 1 388 ? 154.152 181.948 150.292 1.00 91.44  ? 85  A   X N7    1 
ATOM   1619 C  C5    . A   A 1 388 ? 152.846 181.738 149.903 1.00 91.44  ? 85  A   X C5    1 
ATOM   1620 C  C6    . A   A 1 388 ? 151.659 181.598 150.619 1.00 91.44  ? 85  A   X C6    1 
ATOM   1621 N  N6    . A   A 1 388 ? 151.585 181.646 151.945 1.00 91.44  ? 85  A   X N6    1 
ATOM   1622 N  N1    . A   A 1 388 ? 150.530 181.404 149.929 1.00 91.44  ? 85  A   X N1    1 
ATOM   1623 C  C2    . A   A 1 388 ? 150.608 181.350 148.607 1.00 91.44  ? 85  A   X C2    1 
ATOM   1624 N  N3    . A   A 1 388 ? 151.660 181.472 147.819 1.00 91.44  ? 85  A   X N3    1 
ATOM   1625 C  C4    . A   A 1 388 ? 152.757 181.664 148.543 1.00 91.44  ? 85  A   X C4    1 
ATOM   1626 P  P     . G   A 1 389 ? 155.725 183.474 142.955 1.00 97.72  ? 86  G   X P     1 
ATOM   1627 O  OP1   . G   A 1 389 ? 155.735 182.792 141.637 1.00 97.72  ? 86  G   X OP1   1 
ATOM   1628 O  OP2   . G   A 1 389 ? 156.967 184.067 143.509 1.00 97.72  ? 86  G   X OP2   1 
ATOM   1629 O  "O5'" . G   A 1 389 ? 154.613 184.609 142.913 1.00 97.72  ? 86  G   X "O5'" 1 
ATOM   1630 C  "C5'" . G   A 1 389 ? 153.940 184.999 144.098 1.00 97.72  ? 86  G   X "C5'" 1 
ATOM   1631 C  "C4'" . G   A 1 389 ? 152.448 184.868 143.957 1.00 97.72  ? 86  G   X "C4'" 1 
ATOM   1632 O  "O4'" . G   A 1 389 ? 151.957 183.834 144.841 1.00 97.72  ? 86  G   X "O4'" 1 
ATOM   1633 C  "C3'" . G   A 1 389 ? 151.659 186.097 144.346 1.00 97.72  ? 86  G   X "C3'" 1 
ATOM   1634 O  "O3'" . G   A 1 389 ? 151.581 187.017 143.286 1.00 97.72  ? 86  G   X "O3'" 1 
ATOM   1635 C  "C2'" . G   A 1 389 ? 150.316 185.521 144.740 1.00 97.72  ? 86  G   X "C2'" 1 
ATOM   1636 O  "O2'" . G   A 1 389 ? 149.575 185.185 143.584 1.00 97.72  ? 86  G   X "O2'" 1 
ATOM   1637 C  "C1'" . G   A 1 389 ? 150.735 184.227 145.412 1.00 97.72  ? 86  G   X "C1'" 1 
ATOM   1638 N  N9    . G   A 1 389 ? 150.963 184.397 146.851 1.00 97.72  ? 86  G   X N9    1 
ATOM   1639 C  C8    . G   A 1 389 ? 152.189 184.568 147.420 1.00 97.72  ? 86  G   X C8    1 
ATOM   1640 N  N7    . G   A 1 389 ? 152.149 184.676 148.708 1.00 97.72  ? 86  G   X N7    1 
ATOM   1641 C  C5    . G   A 1 389 ? 150.814 184.560 148.999 1.00 97.72  ? 86  G   X C5    1 
ATOM   1642 C  C6    . G   A 1 389 ? 150.190 184.603 150.241 1.00 97.72  ? 86  G   X C6    1 
ATOM   1643 O  O6    . G   A 1 389 ? 150.705 184.759 151.344 1.00 97.72  ? 86  G   X O6    1 
ATOM   1644 N  N1    . G   A 1 389 ? 148.835 184.454 150.115 1.00 97.72  ? 86  G   X N1    1 
ATOM   1645 C  C2    . G   A 1 389 ? 148.164 184.277 148.940 1.00 97.72  ? 86  G   X C2    1 
ATOM   1646 N  N2    . G   A 1 389 ? 146.840 184.149 149.043 1.00 97.72  ? 86  G   X N2    1 
ATOM   1647 N  N3    . G   A 1 389 ? 148.738 184.237 147.762 1.00 97.72  ? 86  G   X N3    1 
ATOM   1648 C  C4    . G   A 1 389 ? 150.061 184.387 147.874 1.00 97.72  ? 86  G   X C4    1 
ATOM   1649 P  P     . U   A 1 390 ? 151.086 188.504 143.570 1.00 106.03 ? 87  U   X P     1 
ATOM   1650 O  OP1   . U   A 1 390 ? 151.218 189.289 142.319 1.00 106.03 ? 87  U   X OP1   1 
ATOM   1651 O  OP2   . U   A 1 390 ? 151.762 188.948 144.807 1.00 106.03 ? 87  U   X OP2   1 
ATOM   1652 O  "O5'" . U   A 1 390 ? 149.545 188.329 143.908 1.00 106.03 ? 87  U   X "O5'" 1 
ATOM   1653 C  "C5'" . U   A 1 390 ? 148.910 189.240 144.775 1.00 106.03 ? 87  U   X "C5'" 1 
ATOM   1654 C  "C4'" . U   A 1 390 ? 147.661 188.663 145.360 1.00 106.03 ? 87  U   X "C4'" 1 
ATOM   1655 O  "O4'" . U   A 1 390 ? 147.957 187.370 145.949 1.00 106.03 ? 87  U   X "O4'" 1 
ATOM   1656 C  "C3'" . U   A 1 390 ? 147.083 189.450 146.516 1.00 106.03 ? 87  U   X "C3'" 1 
ATOM   1657 O  "O3'" . U   A 1 390 ? 146.358 190.605 146.137 1.00 106.03 ? 87  U   X "O3'" 1 
ATOM   1658 C  "C2'" . U   A 1 390 ? 146.279 188.390 147.235 1.00 106.03 ? 87  U   X "C2'" 1 
ATOM   1659 O  "O2'" . U   A 1 390 ? 145.133 188.034 146.477 1.00 106.03 ? 87  U   X "O2'" 1 
ATOM   1660 C  "C1'" . U   A 1 390 ? 147.260 187.236 147.169 1.00 106.03 ? 87  U   X "C1'" 1 
ATOM   1661 N  N1    . U   A 1 390 ? 148.255 187.368 148.244 1.00 106.03 ? 87  U   X N1    1 
ATOM   1662 C  C2    . U   A 1 390 ? 147.880 187.331 149.568 1.00 106.03 ? 87  U   X C2    1 
ATOM   1663 O  O2    . U   A 1 390 ? 146.745 187.165 149.960 1.00 106.03 ? 87  U   X O2    1 
ATOM   1664 N  N3    . U   A 1 390 ? 148.910 187.484 150.449 1.00 106.03 ? 87  U   X N3    1 
ATOM   1665 C  C4    . U   A 1 390 ? 150.236 187.675 150.135 1.00 106.03 ? 87  U   X C4    1 
ATOM   1666 O  O4    . U   A 1 390 ? 151.067 187.808 151.022 1.00 106.03 ? 87  U   X O4    1 
ATOM   1667 C  C5    . U   A 1 390 ? 150.529 187.718 148.753 1.00 106.03 ? 87  U   X C5    1 
ATOM   1668 C  C6    . U   A 1 390 ? 149.550 187.566 147.881 1.00 106.03 ? 87  U   X C6    1 
ATOM   1669 P  P     . G   A 1 391 ? 146.860 192.051 146.637 1.00 125.14 ? 88  G   X P     1 
ATOM   1670 O  OP1   . G   A 1 391 ? 146.145 193.077 145.840 1.00 125.14 ? 88  G   X OP1   1 
ATOM   1671 O  OP2   . G   A 1 391 ? 148.345 192.046 146.656 1.00 125.14 ? 88  G   X OP2   1 
ATOM   1672 O  "O5'" . G   A 1 391 ? 146.356 192.148 148.148 1.00 125.14 ? 88  G   X "O5'" 1 
ATOM   1673 C  "C5'" . G   A 1 391 ? 145.085 192.704 148.452 1.00 125.14 ? 88  G   X "C5'" 1 
ATOM   1674 C  "C4'" . G   A 1 391 ? 144.796 192.697 149.935 1.00 125.14 ? 88  G   X "C4'" 1 
ATOM   1675 O  "O4'" . G   A 1 391 ? 145.013 191.370 150.480 1.00 125.14 ? 88  G   X "O4'" 1 
ATOM   1676 C  "C3'" . G   A 1 391 ? 145.662 193.595 150.805 1.00 125.14 ? 88  G   X "C3'" 1 
ATOM   1677 O  "O3'" . G   A 1 391 ? 145.259 194.953 150.782 1.00 125.14 ? 88  G   X "O3'" 1 
ATOM   1678 C  "C2'" . G   A 1 391 ? 145.529 192.951 152.178 1.00 125.14 ? 88  G   X "C2'" 1 
ATOM   1679 O  "O2'" . G   A 1 391 ? 144.298 193.314 152.787 1.00 125.14 ? 88  G   X "O2'" 1 
ATOM   1680 C  "C1'" . G   A 1 391 ? 145.473 191.468 151.813 1.00 125.14 ? 88  G   X "C1'" 1 
ATOM   1681 N  N9    . G   A 1 391 ? 146.800 190.841 151.898 1.00 125.14 ? 88  G   X N9    1 
ATOM   1682 C  C8    . G   A 1 391 ? 147.551 190.384 150.851 1.00 125.14 ? 88  G   X C8    1 
ATOM   1683 N  N7    . G   A 1 391 ? 148.686 189.881 151.241 1.00 125.14 ? 88  G   X N7    1 
ATOM   1684 C  C5    . G   A 1 391 ? 148.683 190.013 152.615 1.00 125.14 ? 88  G   X C5    1 
ATOM   1685 C  C6    . G   A 1 391 ? 149.655 189.650 153.568 1.00 125.14 ? 88  G   X C6    1 
ATOM   1686 O  O6    . G   A 1 391 ? 150.749 189.112 153.388 1.00 125.14 ? 88  G   X O6    1 
ATOM   1687 N  N1    . G   A 1 391 ? 149.251 189.966 154.854 1.00 125.14 ? 88  G   X N1    1 
ATOM   1688 C  C2    . G   A 1 391 ? 148.063 190.566 155.183 1.00 125.14 ? 88  G   X C2    1 
ATOM   1689 N  N2    . G   A 1 391 ? 147.858 190.792 156.487 1.00 125.14 ? 88  G   X N2    1 
ATOM   1690 N  N3    . G   A 1 391 ? 147.147 190.915 154.299 1.00 125.14 ? 88  G   X N3    1 
ATOM   1691 C  C4    . G   A 1 391 ? 147.524 190.610 153.042 1.00 125.14 ? 88  G   X C4    1 
ATOM   1692 P  P     . C   A 1 392 ? 146.329 196.113 151.085 1.00 133.18 ? 89  C   X P     1 
ATOM   1693 O  OP1   . C   A 1 392 ? 145.668 197.425 150.872 1.00 133.18 ? 89  C   X OP1   1 
ATOM   1694 O  OP2   . C   A 1 392 ? 147.570 195.779 150.341 1.00 133.18 ? 89  C   X OP2   1 
ATOM   1695 O  "O5'" . C   A 1 392 ? 146.647 195.964 152.640 1.00 133.18 ? 89  C   X "O5'" 1 
ATOM   1696 C  "C5'" . C   A 1 392 ? 145.669 196.262 153.627 1.00 133.18 ? 89  C   X "C5'" 1 
ATOM   1697 C  "C4'" . C   A 1 392 ? 146.215 196.052 155.018 1.00 133.18 ? 89  C   X "C4'" 1 
ATOM   1698 O  "O4'" . C   A 1 392 ? 146.555 194.651 155.203 1.00 133.18 ? 89  C   X "O4'" 1 
ATOM   1699 C  "C3'" . C   A 1 392 ? 147.504 196.794 155.341 1.00 133.18 ? 89  C   X "C3'" 1 
ATOM   1700 O  "O3'" . C   A 1 392 ? 147.287 198.143 155.717 1.00 133.18 ? 89  C   X "O3'" 1 
ATOM   1701 C  "C2'" . C   A 1 392 ? 148.115 195.942 156.445 1.00 133.18 ? 89  C   X "C2'" 1 
ATOM   1702 O  "O2'" . C   A 1 392 ? 147.489 196.211 157.690 1.00 133.18 ? 89  C   X "O2'" 1 
ATOM   1703 C  "C1'" . C   A 1 392 ? 147.719 194.535 155.995 1.00 133.18 ? 89  C   X "C1'" 1 
ATOM   1704 N  N1    . C   A 1 392 ? 148.773 193.892 155.179 1.00 133.18 ? 89  C   X N1    1 
ATOM   1705 C  C2    . C   A 1 392 ? 149.907 193.350 155.797 1.00 133.18 ? 89  C   X C2    1 
ATOM   1706 O  O2    . C   A 1 392 ? 150.025 193.416 157.030 1.00 133.18 ? 89  C   X O2    1 
ATOM   1707 N  N3    . C   A 1 392 ? 150.858 192.769 155.033 1.00 133.18 ? 89  C   X N3    1 
ATOM   1708 C  C4    . C   A 1 392 ? 150.705 192.712 153.708 1.00 133.18 ? 89  C   X C4    1 
ATOM   1709 N  N4    . C   A 1 392 ? 151.667 192.129 152.995 1.00 133.18 ? 89  C   X N4    1 
ATOM   1710 C  C5    . C   A 1 392 ? 149.565 193.252 153.052 1.00 133.18 ? 89  C   X C5    1 
ATOM   1711 C  C6    . C   A 1 392 ? 148.634 193.823 153.822 1.00 133.18 ? 89  C   X C6    1 
HETATM 1712 MG MG    . MG  B 2 .   ? 173.274 167.509 156.242 1.00 93.14  ? 201 MG  X MG    1 
HETATM 1713 MG MG    . MG  C 2 .   ? 173.554 167.170 162.200 1.00 92.14  ? 202 MG  X MG    1 
HETATM 1714 N  "N1'" . TPP D 3 .   ? 161.391 164.449 161.699 1.00 89.99  ? 203 TPP X "N1'" 1 
HETATM 1715 C  "C2'" . TPP D 3 .   ? 160.589 164.412 162.758 1.00 89.99  ? 203 TPP X "C2'" 1 
HETATM 1716 C  CM2   . TPP D 3 .   ? 159.144 164.140 162.510 1.00 89.99  ? 203 TPP X CM2   1 
HETATM 1717 N  "N3'" . TPP D 3 .   ? 160.964 164.597 164.023 1.00 89.99  ? 203 TPP X "N3'" 1 
HETATM 1718 C  "C4'" . TPP D 3 .   ? 162.262 164.840 164.262 1.00 89.99  ? 203 TPP X "C4'" 1 
HETATM 1719 N  "N4'" . TPP D 3 .   ? 162.624 165.022 165.533 1.00 89.99  ? 203 TPP X "N4'" 1 
HETATM 1720 C  "C5'" . TPP D 3 .   ? 163.200 164.897 163.203 1.00 89.99  ? 203 TPP X "C5'" 1 
HETATM 1721 C  "C6'" . TPP D 3 .   ? 162.680 164.690 161.948 1.00 89.99  ? 203 TPP X "C6'" 1 
HETATM 1722 C  "C7'" . TPP D 3 .   ? 164.660 165.164 163.419 1.00 89.99  ? 203 TPP X "C7'" 1 
HETATM 1723 N  N3    . TPP D 3 .   ? 165.456 165.155 162.171 1.00 89.99  ? 203 TPP X N3    1 
HETATM 1724 C  C2    . TPP D 3 .   ? 165.718 164.072 161.473 1.00 89.99  ? 203 TPP X C2    1 
HETATM 1725 S  S1    . TPP D 3 .   ? 166.669 164.397 160.135 1.00 89.99  ? 203 TPP X S1    1 
HETATM 1726 C  C5    . TPP D 3 .   ? 166.735 166.071 160.545 1.00 89.99  ? 203 TPP X C5    1 
HETATM 1727 C  C4    . TPP D 3 .   ? 166.037 166.311 161.664 1.00 89.99  ? 203 TPP X C4    1 
HETATM 1728 C  CM4   . TPP D 3 .   ? 165.847 167.615 162.354 1.00 89.99  ? 203 TPP X CM4   1 
HETATM 1729 C  C6    . TPP D 3 .   ? 167.497 167.047 159.694 1.00 89.99  ? 203 TPP X C6    1 
HETATM 1730 C  C7    . TPP D 3 .   ? 168.657 166.417 158.959 1.00 89.99  ? 203 TPP X C7    1 
HETATM 1731 O  O7    . TPP D 3 .   ? 169.703 166.107 159.912 1.00 89.99  ? 203 TPP X O7    1 
HETATM 1732 P  PA    . TPP D 3 .   ? 170.542 167.184 160.687 1.00 89.99  ? 203 TPP X PA    1 
HETATM 1733 O  O1A   . TPP D 3 .   ? 171.788 166.628 161.255 1.00 89.99  ? 203 TPP X O1A   1 
HETATM 1734 O  O2A   . TPP D 3 .   ? 169.652 167.904 161.685 1.00 89.99  ? 203 TPP X O2A   1 
HETATM 1735 O  O3A   . TPP D 3 .   ? 170.899 168.205 159.587 1.00 89.99  ? 203 TPP X O3A   1 
HETATM 1736 P  PB    . TPP D 3 .   ? 172.171 168.938 159.000 1.00 89.99  ? 203 TPP X PB    1 
HETATM 1737 O  O1B   . TPP D 3 .   ? 173.361 168.678 159.856 1.00 89.99  ? 203 TPP X O1B   1 
HETATM 1738 O  O2B   . TPP D 3 .   ? 172.297 168.398 157.591 1.00 89.99  ? 203 TPP X O2B   1 
HETATM 1739 O  O3B   . TPP D 3 .   ? 171.769 170.398 158.948 1.00 89.99  ? 203 TPP X O3B   1 
HETATM 1740 MG MG    . MG  E 2 .   ? 171.857 164.154 159.529 1.00 89.35  ? 204 MG  X MG    1 
HETATM 1741 MG MG    . MG  F 2 .   ? 178.298 159.218 163.183 1.00 90.20  ? 205 MG  X MG    1 
HETATM 1742 MG MG    . MG  G 2 .   ? 171.931 177.231 150.984 1.00 79.87  ? 206 MG  X MG    1 
HETATM 1743 MG MG    . MG  H 2 .   ? 154.901 155.636 170.906 1.00 85.39  ? 207 MG  X MG    1 
HETATM 1744 NA NA    . NA  I 4 .   ? 159.768 165.553 174.359 1.00 66.07  ? 208 NA  X NA    1 
HETATM 1745 NA NA    . NA  J 4 .   ? 160.087 148.390 169.434 1.00 112.16 ? 209 NA  X NA    1 
# 
