data_9C3B
# 
_entry.id   9C3B 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9C3B         pdb_00009c3b 10.2210/pdb9c3b/pdb 
WWPDB D_1000284478 ?            ?                   
EMDB  EMD-45164    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-02-05 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9C3B 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-31 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of the Shigella flexneri bacteriophage Sf14 - tail helical' 
_pdbx_database_related.db_id          EMD-45164 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 4 
_pdbx_contact_author.email              sdoore@ufl.edu 
_pdbx_contact_author.name_first         Sarah 
_pdbx_contact_author.name_last          Doore 
_pdbx_contact_author.name_mi            M. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7672-2355 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Subramanian, S.' 1 ? 
'Kerns, H.R.'     2 ? 
'Braverman, S.G.' 3 ? 
'Doore, S.M.'     4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of the Shigella flexneri bacteriophage Sf14 tail baseplate' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Subramanian, S.' 1 ? 
primary 'Kerns, H.R.'     2 ? 
primary 'Braverman, S.G.' 3 ? 
primary 'Doore, S.M.'     4 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Putative structural protein' 48834.770 1 ? ? ? ? 
2 polymer man gp40                          16204.168 1 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MWNPIVNVDITLNTAGTTREGFGLPLFLASTDNFEERIRGYTSLTEVAEDFDESTAAYKAAKQLWSQTPKVTQLYIGRRT
MQYTVSIPDTVAEGSEYSLTVAIGGGVSQPFQYTAKENDTALIVLNEFKSQIEASPTIKDGVNASVTGTGASATMIITKA
GDNDFVKVTSITPTTSIAATTADTASAALASIETYSTDWYFISAEDRTQQFVLAMASEIQARKKIFFTANADVKALQGTD
LTSATDVPAQLAKSKYTRTVCLWHHTAEFDYPEMAYIAYGAPYDAGSIAWGNAQLTGVAASLQPANQRPLISIQKSALDT
RSCNFIDLDGGVPVVRRGITSGGEWIDIVRGVDWLESDLKTSLRDLLINQKGGKITYDDTGITRIRQVIETSLQRAVNRK
FLSTYTVTVPKASQVALADKKARILKDITFHGILAGAILDVDLKGTVAYE
;
;MWNPIVNVDITLNTAGTTREGFGLPLFLASTDNFEERIRGYTSLTEVAEDFDESTAAYKAAKQLWSQTPKVTQLYIGRRT
MQYTVSIPDTVAEGSEYSLTVAIGGGVSQPFQYTAKENDTALIVLNEFKSQIEASPTIKDGVNASVTGTGASATMIITKA
GDNDFVKVTSITPTTSIAATTADTASAALASIETYSTDWYFISAEDRTQQFVLAMASEIQARKKIFFTANADVKALQGTD
LTSATDVPAQLAKSKYTRTVCLWHHTAEFDYPEMAYIAYGAPYDAGSIAWGNAQLTGVAASLQPANQRPLISIQKSALDT
RSCNFIDLDGGVPVVRRGITSGGEWIDIVRGVDWLESDLKTSLRDLLINQKGGKITYDDTGITRIRQVIETSLQRAVNRK
FLSTYTVTVPKASQVALADKKARILKDITFHGILAGAILDVDLKGTVAYE
;
A ? 
2 'polypeptide(L)' no no 
;MAMYQQYSPKDVVCSWNGIAIEGFAPDSFLRLQRTSPLVTPVVGAGGQVALTRNADKTGTIEIELMQTSLSNQMLSAIQA
KQDDMELEEDISSNFVIYDPSGSVLATGINAWLQELPQIELGRDQNSKTWIFGCEKLDYTSTIPASSV
;
;MAMYQQYSPKDVVCSWNGIAIEGFAPDSFLRLQRTSPLVTPVVGAGGQVALTRNADKTGTIEIELMQTSLSNQMLSAIQA
KQDDMELEEDISSNFVIYDPSGSVLATGINAWLQELPQIELGRDQNSKTWIFGCEKLDYTSTIPASSV
;
B ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   TRP n 
1 3   ASN n 
1 4   PRO n 
1 5   ILE n 
1 6   VAL n 
1 7   ASN n 
1 8   VAL n 
1 9   ASP n 
1 10  ILE n 
1 11  THR n 
1 12  LEU n 
1 13  ASN n 
1 14  THR n 
1 15  ALA n 
1 16  GLY n 
1 17  THR n 
1 18  THR n 
1 19  ARG n 
1 20  GLU n 
1 21  GLY n 
1 22  PHE n 
1 23  GLY n 
1 24  LEU n 
1 25  PRO n 
1 26  LEU n 
1 27  PHE n 
1 28  LEU n 
1 29  ALA n 
1 30  SER n 
1 31  THR n 
1 32  ASP n 
1 33  ASN n 
1 34  PHE n 
1 35  GLU n 
1 36  GLU n 
1 37  ARG n 
1 38  ILE n 
1 39  ARG n 
1 40  GLY n 
1 41  TYR n 
1 42  THR n 
1 43  SER n 
1 44  LEU n 
1 45  THR n 
1 46  GLU n 
1 47  VAL n 
1 48  ALA n 
1 49  GLU n 
1 50  ASP n 
1 51  PHE n 
1 52  ASP n 
1 53  GLU n 
1 54  SER n 
1 55  THR n 
1 56  ALA n 
1 57  ALA n 
1 58  TYR n 
1 59  LYS n 
1 60  ALA n 
1 61  ALA n 
1 62  LYS n 
1 63  GLN n 
1 64  LEU n 
1 65  TRP n 
1 66  SER n 
1 67  GLN n 
1 68  THR n 
1 69  PRO n 
1 70  LYS n 
1 71  VAL n 
1 72  THR n 
1 73  GLN n 
1 74  LEU n 
1 75  TYR n 
1 76  ILE n 
1 77  GLY n 
1 78  ARG n 
1 79  ARG n 
1 80  THR n 
1 81  MET n 
1 82  GLN n 
1 83  TYR n 
1 84  THR n 
1 85  VAL n 
1 86  SER n 
1 87  ILE n 
1 88  PRO n 
1 89  ASP n 
1 90  THR n 
1 91  VAL n 
1 92  ALA n 
1 93  GLU n 
1 94  GLY n 
1 95  SER n 
1 96  GLU n 
1 97  TYR n 
1 98  SER n 
1 99  LEU n 
1 100 THR n 
1 101 VAL n 
1 102 ALA n 
1 103 ILE n 
1 104 GLY n 
1 105 GLY n 
1 106 GLY n 
1 107 VAL n 
1 108 SER n 
1 109 GLN n 
1 110 PRO n 
1 111 PHE n 
1 112 GLN n 
1 113 TYR n 
1 114 THR n 
1 115 ALA n 
1 116 LYS n 
1 117 GLU n 
1 118 ASN n 
1 119 ASP n 
1 120 THR n 
1 121 ALA n 
1 122 LEU n 
1 123 ILE n 
1 124 VAL n 
1 125 LEU n 
1 126 ASN n 
1 127 GLU n 
1 128 PHE n 
1 129 LYS n 
1 130 SER n 
1 131 GLN n 
1 132 ILE n 
1 133 GLU n 
1 134 ALA n 
1 135 SER n 
1 136 PRO n 
1 137 THR n 
1 138 ILE n 
1 139 LYS n 
1 140 ASP n 
1 141 GLY n 
1 142 VAL n 
1 143 ASN n 
1 144 ALA n 
1 145 SER n 
1 146 VAL n 
1 147 THR n 
1 148 GLY n 
1 149 THR n 
1 150 GLY n 
1 151 ALA n 
1 152 SER n 
1 153 ALA n 
1 154 THR n 
1 155 MET n 
1 156 ILE n 
1 157 ILE n 
1 158 THR n 
1 159 LYS n 
1 160 ALA n 
1 161 GLY n 
1 162 ASP n 
1 163 ASN n 
1 164 ASP n 
1 165 PHE n 
1 166 VAL n 
1 167 LYS n 
1 168 VAL n 
1 169 THR n 
1 170 SER n 
1 171 ILE n 
1 172 THR n 
1 173 PRO n 
1 174 THR n 
1 175 THR n 
1 176 SER n 
1 177 ILE n 
1 178 ALA n 
1 179 ALA n 
1 180 THR n 
1 181 THR n 
1 182 ALA n 
1 183 ASP n 
1 184 THR n 
1 185 ALA n 
1 186 SER n 
1 187 ALA n 
1 188 ALA n 
1 189 LEU n 
1 190 ALA n 
1 191 SER n 
1 192 ILE n 
1 193 GLU n 
1 194 THR n 
1 195 TYR n 
1 196 SER n 
1 197 THR n 
1 198 ASP n 
1 199 TRP n 
1 200 TYR n 
1 201 PHE n 
1 202 ILE n 
1 203 SER n 
1 204 ALA n 
1 205 GLU n 
1 206 ASP n 
1 207 ARG n 
1 208 THR n 
1 209 GLN n 
1 210 GLN n 
1 211 PHE n 
1 212 VAL n 
1 213 LEU n 
1 214 ALA n 
1 215 MET n 
1 216 ALA n 
1 217 SER n 
1 218 GLU n 
1 219 ILE n 
1 220 GLN n 
1 221 ALA n 
1 222 ARG n 
1 223 LYS n 
1 224 LYS n 
1 225 ILE n 
1 226 PHE n 
1 227 PHE n 
1 228 THR n 
1 229 ALA n 
1 230 ASN n 
1 231 ALA n 
1 232 ASP n 
1 233 VAL n 
1 234 LYS n 
1 235 ALA n 
1 236 LEU n 
1 237 GLN n 
1 238 GLY n 
1 239 THR n 
1 240 ASP n 
1 241 LEU n 
1 242 THR n 
1 243 SER n 
1 244 ALA n 
1 245 THR n 
1 246 ASP n 
1 247 VAL n 
1 248 PRO n 
1 249 ALA n 
1 250 GLN n 
1 251 LEU n 
1 252 ALA n 
1 253 LYS n 
1 254 SER n 
1 255 LYS n 
1 256 TYR n 
1 257 THR n 
1 258 ARG n 
1 259 THR n 
1 260 VAL n 
1 261 CYS n 
1 262 LEU n 
1 263 TRP n 
1 264 HIS n 
1 265 HIS n 
1 266 THR n 
1 267 ALA n 
1 268 GLU n 
1 269 PHE n 
1 270 ASP n 
1 271 TYR n 
1 272 PRO n 
1 273 GLU n 
1 274 MET n 
1 275 ALA n 
1 276 TYR n 
1 277 ILE n 
1 278 ALA n 
1 279 TYR n 
1 280 GLY n 
1 281 ALA n 
1 282 PRO n 
1 283 TYR n 
1 284 ASP n 
1 285 ALA n 
1 286 GLY n 
1 287 SER n 
1 288 ILE n 
1 289 ALA n 
1 290 TRP n 
1 291 GLY n 
1 292 ASN n 
1 293 ALA n 
1 294 GLN n 
1 295 LEU n 
1 296 THR n 
1 297 GLY n 
1 298 VAL n 
1 299 ALA n 
1 300 ALA n 
1 301 SER n 
1 302 LEU n 
1 303 GLN n 
1 304 PRO n 
1 305 ALA n 
1 306 ASN n 
1 307 GLN n 
1 308 ARG n 
1 309 PRO n 
1 310 LEU n 
1 311 ILE n 
1 312 SER n 
1 313 ILE n 
1 314 GLN n 
1 315 LYS n 
1 316 SER n 
1 317 ALA n 
1 318 LEU n 
1 319 ASP n 
1 320 THR n 
1 321 ARG n 
1 322 SER n 
1 323 CYS n 
1 324 ASN n 
1 325 PHE n 
1 326 ILE n 
1 327 ASP n 
1 328 LEU n 
1 329 ASP n 
1 330 GLY n 
1 331 GLY n 
1 332 VAL n 
1 333 PRO n 
1 334 VAL n 
1 335 VAL n 
1 336 ARG n 
1 337 ARG n 
1 338 GLY n 
1 339 ILE n 
1 340 THR n 
1 341 SER n 
1 342 GLY n 
1 343 GLY n 
1 344 GLU n 
1 345 TRP n 
1 346 ILE n 
1 347 ASP n 
1 348 ILE n 
1 349 VAL n 
1 350 ARG n 
1 351 GLY n 
1 352 VAL n 
1 353 ASP n 
1 354 TRP n 
1 355 LEU n 
1 356 GLU n 
1 357 SER n 
1 358 ASP n 
1 359 LEU n 
1 360 LYS n 
1 361 THR n 
1 362 SER n 
1 363 LEU n 
1 364 ARG n 
1 365 ASP n 
1 366 LEU n 
1 367 LEU n 
1 368 ILE n 
1 369 ASN n 
1 370 GLN n 
1 371 LYS n 
1 372 GLY n 
1 373 GLY n 
1 374 LYS n 
1 375 ILE n 
1 376 THR n 
1 377 TYR n 
1 378 ASP n 
1 379 ASP n 
1 380 THR n 
1 381 GLY n 
1 382 ILE n 
1 383 THR n 
1 384 ARG n 
1 385 ILE n 
1 386 ARG n 
1 387 GLN n 
1 388 VAL n 
1 389 ILE n 
1 390 GLU n 
1 391 THR n 
1 392 SER n 
1 393 LEU n 
1 394 GLN n 
1 395 ARG n 
1 396 ALA n 
1 397 VAL n 
1 398 ASN n 
1 399 ARG n 
1 400 LYS n 
1 401 PHE n 
1 402 LEU n 
1 403 SER n 
1 404 THR n 
1 405 TYR n 
1 406 THR n 
1 407 VAL n 
1 408 THR n 
1 409 VAL n 
1 410 PRO n 
1 411 LYS n 
1 412 ALA n 
1 413 SER n 
1 414 GLN n 
1 415 VAL n 
1 416 ALA n 
1 417 LEU n 
1 418 ALA n 
1 419 ASP n 
1 420 LYS n 
1 421 LYS n 
1 422 ALA n 
1 423 ARG n 
1 424 ILE n 
1 425 LEU n 
1 426 LYS n 
1 427 ASP n 
1 428 ILE n 
1 429 THR n 
1 430 PHE n 
1 431 HIS n 
1 432 GLY n 
1 433 ILE n 
1 434 LEU n 
1 435 ALA n 
1 436 GLY n 
1 437 ALA n 
1 438 ILE n 
1 439 LEU n 
1 440 ASP n 
1 441 VAL n 
1 442 ASP n 
1 443 LEU n 
1 444 LYS n 
1 445 GLY n 
1 446 THR n 
1 447 VAL n 
1 448 ALA n 
1 449 TYR n 
1 450 GLU n 
2 1   MET n 
2 2   ALA n 
2 3   MET n 
2 4   TYR n 
2 5   GLN n 
2 6   GLN n 
2 7   TYR n 
2 8   SER n 
2 9   PRO n 
2 10  LYS n 
2 11  ASP n 
2 12  VAL n 
2 13  VAL n 
2 14  CYS n 
2 15  SER n 
2 16  TRP n 
2 17  ASN n 
2 18  GLY n 
2 19  ILE n 
2 20  ALA n 
2 21  ILE n 
2 22  GLU n 
2 23  GLY n 
2 24  PHE n 
2 25  ALA n 
2 26  PRO n 
2 27  ASP n 
2 28  SER n 
2 29  PHE n 
2 30  LEU n 
2 31  ARG n 
2 32  LEU n 
2 33  GLN n 
2 34  ARG n 
2 35  THR n 
2 36  SER n 
2 37  PRO n 
2 38  LEU n 
2 39  VAL n 
2 40  THR n 
2 41  PRO n 
2 42  VAL n 
2 43  VAL n 
2 44  GLY n 
2 45  ALA n 
2 46  GLY n 
2 47  GLY n 
2 48  GLN n 
2 49  VAL n 
2 50  ALA n 
2 51  LEU n 
2 52  THR n 
2 53  ARG n 
2 54  ASN n 
2 55  ALA n 
2 56  ASP n 
2 57  LYS n 
2 58  THR n 
2 59  GLY n 
2 60  THR n 
2 61  ILE n 
2 62  GLU n 
2 63  ILE n 
2 64  GLU n 
2 65  LEU n 
2 66  MET n 
2 67  GLN n 
2 68  THR n 
2 69  SER n 
2 70  LEU n 
2 71  SER n 
2 72  ASN n 
2 73  GLN n 
2 74  MET n 
2 75  LEU n 
2 76  SER n 
2 77  ALA n 
2 78  ILE n 
2 79  GLN n 
2 80  ALA n 
2 81  LYS n 
2 82  GLN n 
2 83  ASP n 
2 84  ASP n 
2 85  MET n 
2 86  GLU n 
2 87  LEU n 
2 88  GLU n 
2 89  GLU n 
2 90  ASP n 
2 91  ILE n 
2 92  SER n 
2 93  SER n 
2 94  ASN n 
2 95  PHE n 
2 96  VAL n 
2 97  ILE n 
2 98  TYR n 
2 99  ASP n 
2 100 PRO n 
2 101 SER n 
2 102 GLY n 
2 103 SER n 
2 104 VAL n 
2 105 LEU n 
2 106 ALA n 
2 107 THR n 
2 108 GLY n 
2 109 ILE n 
2 110 ASN n 
2 111 ALA n 
2 112 TRP n 
2 113 LEU n 
2 114 GLN n 
2 115 GLU n 
2 116 LEU n 
2 117 PRO n 
2 118 GLN n 
2 119 ILE n 
2 120 GLU n 
2 121 LEU n 
2 122 GLY n 
2 123 ARG n 
2 124 ASP n 
2 125 GLN n 
2 126 ASN n 
2 127 SER n 
2 128 LYS n 
2 129 THR n 
2 130 TRP n 
2 131 ILE n 
2 132 PHE n 
2 133 GLY n 
2 134 CYS n 
2 135 GLU n 
2 136 LYS n 
2 137 LEU n 
2 138 ASP n 
2 139 TYR n 
2 140 THR n 
2 141 SER n 
2 142 THR n 
2 143 ILE n 
2 144 PRO n 
2 145 ALA n 
2 146 SER n 
2 147 SER n 
2 148 VAL n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 450 ? ? Sf14_gp39 ? ? ? ? ? ? 'Shigella phage Sf14' 2024304 ? ? ? ? ? ? ? ? 
'Shigella flexneri Y' 424720 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 148 ? ? Sf14_gp40 ? ? ? ? ? ? 'Shigella phage Sf14' 2024304 ? ? ? ? ? ? ? ? 
'Shigella flexneri Y' 424720 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   TRP 2   2   ?   ?   ?   A . n 
A 1 3   ASN 3   3   ?   ?   ?   A . n 
A 1 4   PRO 4   4   4   PRO PRO A . n 
A 1 5   ILE 5   5   5   ILE ILE A . n 
A 1 6   VAL 6   6   6   VAL VAL A . n 
A 1 7   ASN 7   7   7   ASN ASN A . n 
A 1 8   VAL 8   8   8   VAL VAL A . n 
A 1 9   ASP 9   9   9   ASP ASP A . n 
A 1 10  ILE 10  10  10  ILE ILE A . n 
A 1 11  THR 11  11  11  THR THR A . n 
A 1 12  LEU 12  12  12  LEU LEU A . n 
A 1 13  ASN 13  13  13  ASN ASN A . n 
A 1 14  THR 14  14  14  THR THR A . n 
A 1 15  ALA 15  15  15  ALA ALA A . n 
A 1 16  GLY 16  16  16  GLY GLY A . n 
A 1 17  THR 17  17  17  THR THR A . n 
A 1 18  THR 18  18  18  THR THR A . n 
A 1 19  ARG 19  19  19  ARG ARG A . n 
A 1 20  GLU 20  20  20  GLU ALA A . n 
A 1 21  GLY 21  21  21  GLY GLY A . n 
A 1 22  PHE 22  22  22  PHE PHE A . n 
A 1 23  GLY 23  23  23  GLY GLY A . n 
A 1 24  LEU 24  24  24  LEU LEU A . n 
A 1 25  PRO 25  25  25  PRO PRO A . n 
A 1 26  LEU 26  26  26  LEU LEU A . n 
A 1 27  PHE 27  27  27  PHE PHE A . n 
A 1 28  LEU 28  28  28  LEU LEU A . n 
A 1 29  ALA 29  29  29  ALA ALA A . n 
A 1 30  SER 30  30  30  SER ALA A . n 
A 1 31  THR 31  31  31  THR ALA A . n 
A 1 32  ASP 32  32  32  ASP ALA A . n 
A 1 33  ASN 33  33  33  ASN ASN A . n 
A 1 34  PHE 34  34  34  PHE PHE A . n 
A 1 35  GLU 35  35  35  GLU ALA A . n 
A 1 36  GLU 36  36  36  GLU GLU A . n 
A 1 37  ARG 37  37  37  ARG ARG A . n 
A 1 38  ILE 38  38  38  ILE ILE A . n 
A 1 39  ARG 39  39  39  ARG ARG A . n 
A 1 40  GLY 40  40  40  GLY GLY A . n 
A 1 41  TYR 41  41  41  TYR TYR A . n 
A 1 42  THR 42  42  42  THR THR A . n 
A 1 43  SER 43  43  43  SER SER A . n 
A 1 44  LEU 44  44  44  LEU LEU A . n 
A 1 45  THR 45  45  45  THR THR A . n 
A 1 46  GLU 46  46  46  GLU GLU A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  ALA 48  48  48  ALA ALA A . n 
A 1 49  GLU 49  49  49  GLU GLU A . n 
A 1 50  ASP 50  50  50  ASP ASP A . n 
A 1 51  PHE 51  51  51  PHE PHE A . n 
A 1 52  ASP 52  52  52  ASP ASP A . n 
A 1 53  GLU 53  53  53  GLU GLU A . n 
A 1 54  SER 54  54  54  SER SER A . n 
A 1 55  THR 55  55  55  THR THR A . n 
A 1 56  ALA 56  56  56  ALA ALA A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  TYR 58  58  58  TYR TYR A . n 
A 1 59  LYS 59  59  59  LYS LYS A . n 
A 1 60  ALA 60  60  60  ALA ALA A . n 
A 1 61  ALA 61  61  61  ALA ALA A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  GLN 63  63  63  GLN GLN A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  TRP 65  65  65  TRP TRP A . n 
A 1 66  SER 66  66  66  SER SER A . n 
A 1 67  GLN 67  67  67  GLN GLN A . n 
A 1 68  THR 68  68  68  THR ALA A . n 
A 1 69  PRO 69  69  69  PRO PRO A . n 
A 1 70  LYS 70  70  70  LYS ALA A . n 
A 1 71  VAL 71  71  71  VAL VAL A . n 
A 1 72  THR 72  72  72  THR THR A . n 
A 1 73  GLN 73  73  73  GLN GLN A . n 
A 1 74  LEU 74  74  74  LEU LEU A . n 
A 1 75  TYR 75  75  75  TYR TYR A . n 
A 1 76  ILE 76  76  76  ILE ILE A . n 
A 1 77  GLY 77  77  77  GLY GLY A . n 
A 1 78  ARG 78  78  78  ARG ARG A . n 
A 1 79  ARG 79  79  79  ARG ARG A . n 
A 1 80  THR 80  80  80  THR THR A . n 
A 1 81  MET 81  81  81  MET ALA A . n 
A 1 82  GLN 82  82  82  GLN GLN A . n 
A 1 83  TYR 83  83  83  TYR TYR A . n 
A 1 84  THR 84  84  84  THR THR A . n 
A 1 85  VAL 85  85  85  VAL VAL A . n 
A 1 86  SER 86  86  86  SER ALA A . n 
A 1 87  ILE 87  87  87  ILE ALA A . n 
A 1 88  PRO 88  88  88  PRO PRO A . n 
A 1 89  ASP 89  89  89  ASP ALA A . n 
A 1 90  THR 90  90  90  THR ALA A . n 
A 1 91  VAL 91  91  91  VAL ALA A . n 
A 1 92  ALA 92  92  92  ALA ALA A . n 
A 1 93  GLU 93  93  93  GLU ALA A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  SER 95  95  95  SER ALA A . n 
A 1 96  GLU 96  96  96  GLU ALA A . n 
A 1 97  TYR 97  97  97  TYR ALA A . n 
A 1 98  SER 98  98  98  SER ALA A . n 
A 1 99  LEU 99  99  99  LEU ALA A . n 
A 1 100 THR 100 100 100 THR ALA A . n 
A 1 101 VAL 101 101 101 VAL ALA A . n 
A 1 102 ALA 102 102 102 ALA ALA A . n 
A 1 103 ILE 103 103 103 ILE ALA A . n 
A 1 104 GLY 104 104 104 GLY GLY A . n 
A 1 105 GLY 105 105 105 GLY GLY A . n 
A 1 106 GLY 106 106 106 GLY GLY A . n 
A 1 107 VAL 107 107 107 VAL ALA A . n 
A 1 108 SER 108 108 108 SER ALA A . n 
A 1 109 GLN 109 109 109 GLN ALA A . n 
A 1 110 PRO 110 110 110 PRO PRO A . n 
A 1 111 PHE 111 111 111 PHE ALA A . n 
A 1 112 GLN 112 112 112 GLN ALA A . n 
A 1 113 TYR 113 113 113 TYR ALA A . n 
A 1 114 THR 114 114 114 THR ALA A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 LYS 116 116 116 LYS ALA A . n 
A 1 117 GLU 117 117 117 GLU ALA A . n 
A 1 118 ASN 118 118 118 ASN ALA A . n 
A 1 119 ASP 119 119 119 ASP ALA A . n 
A 1 120 THR 120 120 120 THR ALA A . n 
A 1 121 ALA 121 121 121 ALA ALA A . n 
A 1 122 LEU 122 122 122 LEU LEU A . n 
A 1 123 ILE 123 123 123 ILE ALA A . n 
A 1 124 VAL 124 124 124 VAL VAL A . n 
A 1 125 LEU 125 125 125 LEU LEU A . n 
A 1 126 ASN 126 126 126 ASN ASN A . n 
A 1 127 GLU 127 127 127 GLU ALA A . n 
A 1 128 PHE 128 128 128 PHE PHE A . n 
A 1 129 LYS 129 129 129 LYS ALA A . n 
A 1 130 SER 130 130 130 SER SER A . n 
A 1 131 GLN 131 131 131 GLN GLN A . n 
A 1 132 ILE 132 132 132 ILE ILE A . n 
A 1 133 GLU 133 133 133 GLU GLU A . n 
A 1 134 ALA 134 134 134 ALA ALA A . n 
A 1 135 SER 135 135 135 SER SER A . n 
A 1 136 PRO 136 136 136 PRO PRO A . n 
A 1 137 THR 137 137 137 THR THR A . n 
A 1 138 ILE 138 138 138 ILE ILE A . n 
A 1 139 LYS 139 139 139 LYS LYS A . n 
A 1 140 ASP 140 140 140 ASP ASP A . n 
A 1 141 GLY 141 141 141 GLY GLY A . n 
A 1 142 VAL 142 142 142 VAL VAL A . n 
A 1 143 ASN 143 143 143 ASN ASN A . n 
A 1 144 ALA 144 144 144 ALA ALA A . n 
A 1 145 SER 145 145 145 SER SER A . n 
A 1 146 VAL 146 146 146 VAL VAL A . n 
A 1 147 THR 147 147 147 THR ALA A . n 
A 1 148 GLY 148 148 148 GLY GLY A . n 
A 1 149 THR 149 149 149 THR ALA A . n 
A 1 150 GLY 150 150 150 GLY GLY A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 SER 152 152 152 SER ALA A . n 
A 1 153 ALA 153 153 153 ALA ALA A . n 
A 1 154 THR 154 154 154 THR THR A . n 
A 1 155 MET 155 155 155 MET MET A . n 
A 1 156 ILE 156 156 156 ILE ILE A . n 
A 1 157 ILE 157 157 157 ILE ILE A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 LYS 159 159 159 LYS ALA A . n 
A 1 160 ALA 160 160 160 ALA ALA A . n 
A 1 161 GLY 161 161 161 GLY GLY A . n 
A 1 162 ASP 162 162 162 ASP ALA A . n 
A 1 163 ASN 163 163 163 ASN ALA A . n 
A 1 164 ASP 164 164 164 ASP ALA A . n 
A 1 165 PHE 165 165 165 PHE PHE A . n 
A 1 166 VAL 166 166 166 VAL VAL A . n 
A 1 167 LYS 167 167 167 LYS LYS A . n 
A 1 168 VAL 168 168 168 VAL VAL A . n 
A 1 169 THR 169 169 169 THR THR A . n 
A 1 170 SER 170 170 170 SER SER A . n 
A 1 171 ILE 171 171 171 ILE ALA A . n 
A 1 172 THR 172 172 172 THR ALA A . n 
A 1 173 PRO 173 173 173 PRO PRO A . n 
A 1 174 THR 174 174 174 THR THR A . n 
A 1 175 THR 175 175 175 THR ALA A . n 
A 1 176 SER 176 176 176 SER ALA A . n 
A 1 177 ILE 177 177 177 ILE ILE A . n 
A 1 178 ALA 178 178 178 ALA ALA A . n 
A 1 179 ALA 179 179 179 ALA ALA A . n 
A 1 180 THR 180 180 180 THR THR A . n 
A 1 181 THR 181 181 181 THR THR A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 ASP 183 183 183 ASP ASP A . n 
A 1 184 THR 184 184 184 THR THR A . n 
A 1 185 ALA 185 185 185 ALA ALA A . n 
A 1 186 SER 186 186 186 SER SER A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 LEU 189 189 189 LEU LEU A . n 
A 1 190 ALA 190 190 190 ALA ALA A . n 
A 1 191 SER 191 191 191 SER SER A . n 
A 1 192 ILE 192 192 192 ILE ILE A . n 
A 1 193 GLU 193 193 193 GLU GLU A . n 
A 1 194 THR 194 194 194 THR THR A . n 
A 1 195 TYR 195 195 195 TYR TYR A . n 
A 1 196 SER 196 196 196 SER SER A . n 
A 1 197 THR 197 197 197 THR THR A . n 
A 1 198 ASP 198 198 198 ASP ASP A . n 
A 1 199 TRP 199 199 199 TRP TRP A . n 
A 1 200 TYR 200 200 200 TYR TYR A . n 
A 1 201 PHE 201 201 201 PHE PHE A . n 
A 1 202 ILE 202 202 202 ILE ILE A . n 
A 1 203 SER 203 203 203 SER SER A . n 
A 1 204 ALA 204 204 204 ALA ALA A . n 
A 1 205 GLU 205 205 205 GLU GLU A . n 
A 1 206 ASP 206 206 206 ASP ASP A . n 
A 1 207 ARG 207 207 207 ARG ARG A . n 
A 1 208 THR 208 208 208 THR THR A . n 
A 1 209 GLN 209 209 209 GLN GLN A . n 
A 1 210 GLN 210 210 210 GLN GLN A . n 
A 1 211 PHE 211 211 211 PHE PHE A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 LEU 213 213 213 LEU LEU A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 MET 215 215 215 MET MET A . n 
A 1 216 ALA 216 216 216 ALA ALA A . n 
A 1 217 SER 217 217 217 SER SER A . n 
A 1 218 GLU 218 218 218 GLU GLU A . n 
A 1 219 ILE 219 219 219 ILE ILE A . n 
A 1 220 GLN 220 220 220 GLN GLN A . n 
A 1 221 ALA 221 221 221 ALA ALA A . n 
A 1 222 ARG 222 222 222 ARG ARG A . n 
A 1 223 LYS 223 223 223 LYS LYS A . n 
A 1 224 LYS 224 224 224 LYS LYS A . n 
A 1 225 ILE 225 225 225 ILE ILE A . n 
A 1 226 PHE 226 226 226 PHE PHE A . n 
A 1 227 PHE 227 227 227 PHE PHE A . n 
A 1 228 THR 228 228 228 THR THR A . n 
A 1 229 ALA 229 229 229 ALA ALA A . n 
A 1 230 ASN 230 230 230 ASN ASN A . n 
A 1 231 ALA 231 231 231 ALA ALA A . n 
A 1 232 ASP 232 232 232 ASP ASP A . n 
A 1 233 VAL 233 233 233 VAL VAL A . n 
A 1 234 LYS 234 234 234 LYS LYS A . n 
A 1 235 ALA 235 235 235 ALA ALA A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 GLN 237 237 237 GLN GLN A . n 
A 1 238 GLY 238 238 238 GLY GLY A . n 
A 1 239 THR 239 239 239 THR THR A . n 
A 1 240 ASP 240 240 240 ASP ASP A . n 
A 1 241 LEU 241 241 241 LEU LEU A . n 
A 1 242 THR 242 242 242 THR THR A . n 
A 1 243 SER 243 243 243 SER ALA A . n 
A 1 244 ALA 244 244 244 ALA ALA A . n 
A 1 245 THR 245 245 245 THR ALA A . n 
A 1 246 ASP 246 246 246 ASP ASP A . n 
A 1 247 VAL 247 247 247 VAL VAL A . n 
A 1 248 PRO 248 248 248 PRO PRO A . n 
A 1 249 ALA 249 249 249 ALA ALA A . n 
A 1 250 GLN 250 250 250 GLN GLN A . n 
A 1 251 LEU 251 251 251 LEU LEU A . n 
A 1 252 ALA 252 252 252 ALA ALA A . n 
A 1 253 LYS 253 253 253 LYS LYS A . n 
A 1 254 SER 254 254 254 SER SER A . n 
A 1 255 LYS 255 255 255 LYS LYS A . n 
A 1 256 TYR 256 256 256 TYR TYR A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 ARG 258 258 258 ARG ARG A . n 
A 1 259 THR 259 259 259 THR THR A . n 
A 1 260 VAL 260 260 260 VAL VAL A . n 
A 1 261 CYS 261 261 261 CYS CYS A . n 
A 1 262 LEU 262 262 262 LEU LEU A . n 
A 1 263 TRP 263 263 263 TRP TRP A . n 
A 1 264 HIS 264 264 264 HIS HIS A . n 
A 1 265 HIS 265 265 265 HIS HIS A . n 
A 1 266 THR 266 266 266 THR THR A . n 
A 1 267 ALA 267 267 267 ALA ALA A . n 
A 1 268 GLU 268 268 268 GLU GLU A . n 
A 1 269 PHE 269 269 269 PHE ALA A . n 
A 1 270 ASP 270 270 270 ASP ASP A . n 
A 1 271 TYR 271 271 271 TYR TYR A . n 
A 1 272 PRO 272 272 272 PRO PRO A . n 
A 1 273 GLU 273 273 273 GLU GLU A . n 
A 1 274 MET 274 274 274 MET MET A . n 
A 1 275 ALA 275 275 275 ALA ALA A . n 
A 1 276 TYR 276 276 276 TYR TYR A . n 
A 1 277 ILE 277 277 277 ILE ILE A . n 
A 1 278 ALA 278 278 278 ALA ALA A . n 
A 1 279 TYR 279 279 279 TYR TYR A . n 
A 1 280 GLY 280 280 280 GLY GLY A . n 
A 1 281 ALA 281 281 281 ALA ALA A . n 
A 1 282 PRO 282 282 282 PRO PRO A . n 
A 1 283 TYR 283 283 283 TYR TYR A . n 
A 1 284 ASP 284 284 284 ASP ASP A . n 
A 1 285 ALA 285 285 285 ALA ALA A . n 
A 1 286 GLY 286 286 286 GLY GLY A . n 
A 1 287 SER 287 287 287 SER SER A . n 
A 1 288 ILE 288 288 288 ILE ILE A . n 
A 1 289 ALA 289 289 289 ALA ALA A . n 
A 1 290 TRP 290 290 290 TRP TRP A . n 
A 1 291 GLY 291 291 291 GLY GLY A . n 
A 1 292 ASN 292 292 292 ASN ASN A . n 
A 1 293 ALA 293 293 293 ALA ALA A . n 
A 1 294 GLN 294 294 294 GLN GLN A . n 
A 1 295 LEU 295 295 295 LEU LEU A . n 
A 1 296 THR 296 296 296 THR THR A . n 
A 1 297 GLY 297 297 297 GLY GLY A . n 
A 1 298 VAL 298 298 298 VAL VAL A . n 
A 1 299 ALA 299 299 299 ALA ALA A . n 
A 1 300 ALA 300 300 300 ALA ALA A . n 
A 1 301 SER 301 301 301 SER SER A . n 
A 1 302 LEU 302 302 302 LEU LEU A . n 
A 1 303 GLN 303 303 303 GLN GLN A . n 
A 1 304 PRO 304 304 304 PRO PRO A . n 
A 1 305 ALA 305 305 305 ALA ALA A . n 
A 1 306 ASN 306 306 306 ASN ASN A . n 
A 1 307 GLN 307 307 307 GLN GLN A . n 
A 1 308 ARG 308 308 308 ARG ARG A . n 
A 1 309 PRO 309 309 309 PRO PRO A . n 
A 1 310 LEU 310 310 310 LEU LEU A . n 
A 1 311 ILE 311 311 311 ILE ILE A . n 
A 1 312 SER 312 312 312 SER SER A . n 
A 1 313 ILE 313 313 313 ILE ILE A . n 
A 1 314 GLN 314 314 314 GLN GLN A . n 
A 1 315 LYS 315 315 315 LYS LYS A . n 
A 1 316 SER 316 316 316 SER SER A . n 
A 1 317 ALA 317 317 317 ALA ALA A . n 
A 1 318 LEU 318 318 318 LEU LEU A . n 
A 1 319 ASP 319 319 319 ASP ASP A . n 
A 1 320 THR 320 320 320 THR THR A . n 
A 1 321 ARG 321 321 321 ARG ARG A . n 
A 1 322 SER 322 322 322 SER SER A . n 
A 1 323 CYS 323 323 323 CYS CYS A . n 
A 1 324 ASN 324 324 324 ASN ASN A . n 
A 1 325 PHE 325 325 325 PHE PHE A . n 
A 1 326 ILE 326 326 326 ILE ILE A . n 
A 1 327 ASP 327 327 327 ASP ASP A . n 
A 1 328 LEU 328 328 328 LEU LEU A . n 
A 1 329 ASP 329 329 329 ASP ASP A . n 
A 1 330 GLY 330 330 330 GLY GLY A . n 
A 1 331 GLY 331 331 331 GLY GLY A . n 
A 1 332 VAL 332 332 332 VAL VAL A . n 
A 1 333 PRO 333 333 333 PRO PRO A . n 
A 1 334 VAL 334 334 334 VAL VAL A . n 
A 1 335 VAL 335 335 335 VAL VAL A . n 
A 1 336 ARG 336 336 336 ARG ARG A . n 
A 1 337 ARG 337 337 337 ARG ARG A . n 
A 1 338 GLY 338 338 338 GLY GLY A . n 
A 1 339 ILE 339 339 339 ILE ILE A . n 
A 1 340 THR 340 340 340 THR THR A . n 
A 1 341 SER 341 341 341 SER SER A . n 
A 1 342 GLY 342 342 342 GLY GLY A . n 
A 1 343 GLY 343 343 343 GLY GLY A . n 
A 1 344 GLU 344 344 344 GLU GLU A . n 
A 1 345 TRP 345 345 345 TRP TRP A . n 
A 1 346 ILE 346 346 346 ILE ILE A . n 
A 1 347 ASP 347 347 347 ASP ASP A . n 
A 1 348 ILE 348 348 348 ILE ILE A . n 
A 1 349 VAL 349 349 349 VAL VAL A . n 
A 1 350 ARG 350 350 350 ARG ARG A . n 
A 1 351 GLY 351 351 351 GLY GLY A . n 
A 1 352 VAL 352 352 352 VAL VAL A . n 
A 1 353 ASP 353 353 353 ASP ASP A . n 
A 1 354 TRP 354 354 354 TRP TRP A . n 
A 1 355 LEU 355 355 355 LEU LEU A . n 
A 1 356 GLU 356 356 356 GLU ALA A . n 
A 1 357 SER 357 357 357 SER SER A . n 
A 1 358 ASP 358 358 358 ASP ASP A . n 
A 1 359 LEU 359 359 359 LEU LEU A . n 
A 1 360 LYS 360 360 360 LYS LYS A . n 
A 1 361 THR 361 361 361 THR THR A . n 
A 1 362 SER 362 362 362 SER SER A . n 
A 1 363 LEU 363 363 363 LEU LEU A . n 
A 1 364 ARG 364 364 364 ARG ARG A . n 
A 1 365 ASP 365 365 365 ASP ASP A . n 
A 1 366 LEU 366 366 366 LEU LEU A . n 
A 1 367 LEU 367 367 367 LEU LEU A . n 
A 1 368 ILE 368 368 368 ILE ILE A . n 
A 1 369 ASN 369 369 369 ASN ASN A . n 
A 1 370 GLN 370 370 370 GLN GLN A . n 
A 1 371 LYS 371 371 371 LYS LYS A . n 
A 1 372 GLY 372 372 372 GLY GLY A . n 
A 1 373 GLY 373 373 373 GLY GLY A . n 
A 1 374 LYS 374 374 374 LYS LYS A . n 
A 1 375 ILE 375 375 375 ILE ILE A . n 
A 1 376 THR 376 376 376 THR THR A . n 
A 1 377 TYR 377 377 377 TYR TYR A . n 
A 1 378 ASP 378 378 378 ASP ASP A . n 
A 1 379 ASP 379 379 379 ASP ASP A . n 
A 1 380 THR 380 380 380 THR THR A . n 
A 1 381 GLY 381 381 381 GLY GLY A . n 
A 1 382 ILE 382 382 382 ILE ILE A . n 
A 1 383 THR 383 383 383 THR THR A . n 
A 1 384 ARG 384 384 384 ARG ARG A . n 
A 1 385 ILE 385 385 385 ILE ILE A . n 
A 1 386 ARG 386 386 386 ARG ARG A . n 
A 1 387 GLN 387 387 387 GLN GLN A . n 
A 1 388 VAL 388 388 388 VAL VAL A . n 
A 1 389 ILE 389 389 389 ILE ILE A . n 
A 1 390 GLU 390 390 390 GLU GLU A . n 
A 1 391 THR 391 391 391 THR THR A . n 
A 1 392 SER 392 392 392 SER SER A . n 
A 1 393 LEU 393 393 393 LEU LEU A . n 
A 1 394 GLN 394 394 394 GLN GLN A . n 
A 1 395 ARG 395 395 395 ARG ARG A . n 
A 1 396 ALA 396 396 396 ALA ALA A . n 
A 1 397 VAL 397 397 397 VAL VAL A . n 
A 1 398 ASN 398 398 398 ASN ASN A . n 
A 1 399 ARG 399 399 399 ARG ARG A . n 
A 1 400 LYS 400 400 400 LYS LYS A . n 
A 1 401 PHE 401 401 401 PHE PHE A . n 
A 1 402 LEU 402 402 402 LEU LEU A . n 
A 1 403 SER 403 403 403 SER SER A . n 
A 1 404 THR 404 404 404 THR THR A . n 
A 1 405 TYR 405 405 405 TYR TYR A . n 
A 1 406 THR 406 406 406 THR THR A . n 
A 1 407 VAL 407 407 407 VAL VAL A . n 
A 1 408 THR 408 408 408 THR THR A . n 
A 1 409 VAL 409 409 409 VAL VAL A . n 
A 1 410 PRO 410 410 410 PRO PRO A . n 
A 1 411 LYS 411 411 411 LYS LYS A . n 
A 1 412 ALA 412 412 412 ALA ALA A . n 
A 1 413 SER 413 413 413 SER SER A . n 
A 1 414 GLN 414 414 414 GLN GLN A . n 
A 1 415 VAL 415 415 415 VAL VAL A . n 
A 1 416 ALA 416 416 416 ALA ALA A . n 
A 1 417 LEU 417 417 417 LEU LEU A . n 
A 1 418 ALA 418 418 418 ALA ALA A . n 
A 1 419 ASP 419 419 419 ASP ASP A . n 
A 1 420 LYS 420 420 420 LYS LYS A . n 
A 1 421 LYS 421 421 421 LYS LYS A . n 
A 1 422 ALA 422 422 422 ALA ALA A . n 
A 1 423 ARG 423 423 423 ARG ARG A . n 
A 1 424 ILE 424 424 424 ILE ILE A . n 
A 1 425 LEU 425 425 425 LEU LEU A . n 
A 1 426 LYS 426 426 426 LYS LYS A . n 
A 1 427 ASP 427 427 427 ASP ASP A . n 
A 1 428 ILE 428 428 428 ILE ILE A . n 
A 1 429 THR 429 429 429 THR THR A . n 
A 1 430 PHE 430 430 430 PHE PHE A . n 
A 1 431 HIS 431 431 431 HIS HIS A . n 
A 1 432 GLY 432 432 432 GLY GLY A . n 
A 1 433 ILE 433 433 433 ILE ILE A . n 
A 1 434 LEU 434 434 434 LEU LEU A . n 
A 1 435 ALA 435 435 435 ALA ALA A . n 
A 1 436 GLY 436 436 436 GLY GLY A . n 
A 1 437 ALA 437 437 437 ALA ALA A . n 
A 1 438 ILE 438 438 438 ILE ILE A . n 
A 1 439 LEU 439 439 439 LEU LEU A . n 
A 1 440 ASP 440 440 440 ASP ASP A . n 
A 1 441 VAL 441 441 441 VAL VAL A . n 
A 1 442 ASP 442 442 442 ASP ASP A . n 
A 1 443 LEU 443 443 443 LEU LEU A . n 
A 1 444 LYS 444 444 444 LYS LYS A . n 
A 1 445 GLY 445 445 445 GLY GLY A . n 
A 1 446 THR 446 446 446 THR THR A . n 
A 1 447 VAL 447 447 447 VAL VAL A . n 
A 1 448 ALA 448 448 448 ALA ALA A . n 
A 1 449 TYR 449 449 ?   ?   ?   A . n 
A 1 450 GLU 450 450 ?   ?   ?   A . n 
B 2 1   MET 1   1   ?   ?   ?   B . n 
B 2 2   ALA 2   2   2   ALA ALA B . n 
B 2 3   MET 3   3   3   MET MET B . n 
B 2 4   TYR 4   4   4   TYR TYR B . n 
B 2 5   GLN 5   5   5   GLN GLN B . n 
B 2 6   GLN 6   6   6   GLN GLN B . n 
B 2 7   TYR 7   7   7   TYR TYR B . n 
B 2 8   SER 8   8   8   SER SER B . n 
B 2 9   PRO 9   9   9   PRO PRO B . n 
B 2 10  LYS 10  10  10  LYS LYS B . n 
B 2 11  ASP 11  11  11  ASP ASP B . n 
B 2 12  VAL 12  12  12  VAL VAL B . n 
B 2 13  VAL 13  13  13  VAL VAL B . n 
B 2 14  CYS 14  14  14  CYS CYS B . n 
B 2 15  SER 15  15  15  SER SER B . n 
B 2 16  TRP 16  16  16  TRP TRP B . n 
B 2 17  ASN 17  17  17  ASN ASN B . n 
B 2 18  GLY 18  18  18  GLY GLY B . n 
B 2 19  ILE 19  19  19  ILE ILE B . n 
B 2 20  ALA 20  20  20  ALA ALA B . n 
B 2 21  ILE 21  21  21  ILE ILE B . n 
B 2 22  GLU 22  22  22  GLU GLU B . n 
B 2 23  GLY 23  23  23  GLY GLY B . n 
B 2 24  PHE 24  24  24  PHE PHE B . n 
B 2 25  ALA 25  25  25  ALA ALA B . n 
B 2 26  PRO 26  26  26  PRO PRO B . n 
B 2 27  ASP 27  27  27  ASP ASP B . n 
B 2 28  SER 28  28  28  SER SER B . n 
B 2 29  PHE 29  29  29  PHE PHE B . n 
B 2 30  LEU 30  30  30  LEU LEU B . n 
B 2 31  ARG 31  31  31  ARG ARG B . n 
B 2 32  LEU 32  32  32  LEU LEU B . n 
B 2 33  GLN 33  33  33  GLN GLN B . n 
B 2 34  ARG 34  34  34  ARG ARG B . n 
B 2 35  THR 35  35  35  THR THR B . n 
B 2 36  SER 36  36  36  SER SER B . n 
B 2 37  PRO 37  37  37  PRO PRO B . n 
B 2 38  LEU 38  38  38  LEU LEU B . n 
B 2 39  VAL 39  39  39  VAL VAL B . n 
B 2 40  THR 40  40  40  THR THR B . n 
B 2 41  PRO 41  41  41  PRO PRO B . n 
B 2 42  VAL 42  42  42  VAL VAL B . n 
B 2 43  VAL 43  43  43  VAL VAL B . n 
B 2 44  GLY 44  44  44  GLY GLY B . n 
B 2 45  ALA 45  45  45  ALA ALA B . n 
B 2 46  GLY 46  46  46  GLY GLY B . n 
B 2 47  GLY 47  47  47  GLY GLY B . n 
B 2 48  GLN 48  48  48  GLN GLN B . n 
B 2 49  VAL 49  49  49  VAL VAL B . n 
B 2 50  ALA 50  50  50  ALA ALA B . n 
B 2 51  LEU 51  51  51  LEU LEU B . n 
B 2 52  THR 52  52  52  THR THR B . n 
B 2 53  ARG 53  53  53  ARG ARG B . n 
B 2 54  ASN 54  54  54  ASN ASN B . n 
B 2 55  ALA 55  55  55  ALA ALA B . n 
B 2 56  ASP 56  56  56  ASP ASP B . n 
B 2 57  LYS 57  57  57  LYS LYS B . n 
B 2 58  THR 58  58  58  THR THR B . n 
B 2 59  GLY 59  59  59  GLY GLY B . n 
B 2 60  THR 60  60  60  THR THR B . n 
B 2 61  ILE 61  61  61  ILE ILE B . n 
B 2 62  GLU 62  62  62  GLU GLU B . n 
B 2 63  ILE 63  63  63  ILE ILE B . n 
B 2 64  GLU 64  64  64  GLU GLU B . n 
B 2 65  LEU 65  65  65  LEU LEU B . n 
B 2 66  MET 66  66  66  MET MET B . n 
B 2 67  GLN 67  67  67  GLN GLN B . n 
B 2 68  THR 68  68  68  THR THR B . n 
B 2 69  SER 69  69  69  SER SER B . n 
B 2 70  LEU 70  70  70  LEU LEU B . n 
B 2 71  SER 71  71  71  SER SER B . n 
B 2 72  ASN 72  72  72  ASN ASN B . n 
B 2 73  GLN 73  73  73  GLN GLN B . n 
B 2 74  MET 74  74  74  MET ALA B . n 
B 2 75  LEU 75  75  75  LEU LEU B . n 
B 2 76  SER 76  76  76  SER SER B . n 
B 2 77  ALA 77  77  77  ALA ALA B . n 
B 2 78  ILE 78  78  78  ILE ILE B . n 
B 2 79  GLN 79  79  79  GLN GLN B . n 
B 2 80  ALA 80  80  80  ALA ALA B . n 
B 2 81  LYS 81  81  81  LYS LYS B . n 
B 2 82  GLN 82  82  82  GLN GLN B . n 
B 2 83  ASP 83  83  83  ASP ASP B . n 
B 2 84  ASP 84  84  84  ASP ASP B . n 
B 2 85  MET 85  85  85  MET MET B . n 
B 2 86  GLU 86  86  86  GLU ALA B . n 
B 2 87  LEU 87  87  87  LEU LEU B . n 
B 2 88  GLU 88  88  88  GLU GLU B . n 
B 2 89  GLU 89  89  89  GLU GLU B . n 
B 2 90  ASP 90  90  90  ASP ASP B . n 
B 2 91  ILE 91  91  91  ILE ILE B . n 
B 2 92  SER 92  92  92  SER SER B . n 
B 2 93  SER 93  93  93  SER SER B . n 
B 2 94  ASN 94  94  94  ASN ASN B . n 
B 2 95  PHE 95  95  95  PHE PHE B . n 
B 2 96  VAL 96  96  96  VAL VAL B . n 
B 2 97  ILE 97  97  97  ILE ILE B . n 
B 2 98  TYR 98  98  98  TYR TYR B . n 
B 2 99  ASP 99  99  99  ASP ASP B . n 
B 2 100 PRO 100 100 100 PRO PRO B . n 
B 2 101 SER 101 101 101 SER SER B . n 
B 2 102 GLY 102 102 102 GLY GLY B . n 
B 2 103 SER 103 103 103 SER SER B . n 
B 2 104 VAL 104 104 104 VAL VAL B . n 
B 2 105 LEU 105 105 105 LEU LEU B . n 
B 2 106 ALA 106 106 106 ALA ALA B . n 
B 2 107 THR 107 107 107 THR THR B . n 
B 2 108 GLY 108 108 108 GLY GLY B . n 
B 2 109 ILE 109 109 109 ILE ILE B . n 
B 2 110 ASN 110 110 110 ASN ASN B . n 
B 2 111 ALA 111 111 111 ALA ALA B . n 
B 2 112 TRP 112 112 112 TRP TRP B . n 
B 2 113 LEU 113 113 113 LEU LEU B . n 
B 2 114 GLN 114 114 114 GLN GLN B . n 
B 2 115 GLU 115 115 115 GLU GLU B . n 
B 2 116 LEU 116 116 116 LEU LEU B . n 
B 2 117 PRO 117 117 117 PRO PRO B . n 
B 2 118 GLN 118 118 118 GLN GLN B . n 
B 2 119 ILE 119 119 119 ILE ILE B . n 
B 2 120 GLU 120 120 120 GLU GLU B . n 
B 2 121 LEU 121 121 121 LEU LEU B . n 
B 2 122 GLY 122 122 122 GLY GLY B . n 
B 2 123 ARG 123 123 123 ARG ARG B . n 
B 2 124 ASP 124 124 124 ASP ASP B . n 
B 2 125 GLN 125 125 125 GLN GLN B . n 
B 2 126 ASN 126 126 126 ASN ASN B . n 
B 2 127 SER 127 127 127 SER SER B . n 
B 2 128 LYS 128 128 128 LYS LYS B . n 
B 2 129 THR 129 129 129 THR THR B . n 
B 2 130 TRP 130 130 130 TRP TRP B . n 
B 2 131 ILE 131 131 131 ILE ILE B . n 
B 2 132 PHE 132 132 132 PHE PHE B . n 
B 2 133 GLY 133 133 133 GLY GLY B . n 
B 2 134 CYS 134 134 134 CYS CYS B . n 
B 2 135 GLU 135 135 135 GLU GLU B . n 
B 2 136 LYS 136 136 136 LYS LYS B . n 
B 2 137 LEU 137 137 137 LEU LEU B . n 
B 2 138 ASP 138 138 138 ASP ASP B . n 
B 2 139 TYR 139 139 139 TYR TYR B . n 
B 2 140 THR 140 140 140 THR THR B . n 
B 2 141 SER 141 141 141 SER SER B . n 
B 2 142 THR 142 142 142 THR THR B . n 
B 2 143 ILE 143 143 143 ILE ILE B . n 
B 2 144 PRO 144 144 144 PRO PRO B . n 
B 2 145 ALA 145 145 ?   ?   ?   B . n 
B 2 146 SER 146 146 ?   ?   ?   B . n 
B 2 147 SER 147 147 ?   ?   ?   B . n 
B 2 148 VAL 148 148 ?   ?   ?   B . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A GLU 20  ? CG  ? A GLU 20  CG  
2   1 Y 1 A GLU 20  ? CD  ? A GLU 20  CD  
3   1 Y 1 A GLU 20  ? OE1 ? A GLU 20  OE1 
4   1 Y 1 A GLU 20  ? OE2 ? A GLU 20  OE2 
5   1 Y 1 A SER 30  ? OG  ? A SER 30  OG  
6   1 Y 1 A THR 31  ? OG1 ? A THR 31  OG1 
7   1 Y 1 A THR 31  ? CG2 ? A THR 31  CG2 
8   1 Y 1 A ASP 32  ? CG  ? A ASP 32  CG  
9   1 Y 1 A ASP 32  ? OD1 ? A ASP 32  OD1 
10  1 Y 1 A ASP 32  ? OD2 ? A ASP 32  OD2 
11  1 Y 1 A GLU 35  ? CG  ? A GLU 35  CG  
12  1 Y 1 A GLU 35  ? CD  ? A GLU 35  CD  
13  1 Y 1 A GLU 35  ? OE1 ? A GLU 35  OE1 
14  1 Y 1 A GLU 35  ? OE2 ? A GLU 35  OE2 
15  1 Y 1 A THR 68  ? OG1 ? A THR 68  OG1 
16  1 Y 1 A THR 68  ? CG2 ? A THR 68  CG2 
17  1 Y 1 A LYS 70  ? CG  ? A LYS 70  CG  
18  1 Y 1 A LYS 70  ? CD  ? A LYS 70  CD  
19  1 Y 1 A LYS 70  ? CE  ? A LYS 70  CE  
20  1 Y 1 A LYS 70  ? NZ  ? A LYS 70  NZ  
21  1 Y 1 A MET 81  ? CG  ? A MET 81  CG  
22  1 Y 1 A MET 81  ? SD  ? A MET 81  SD  
23  1 Y 1 A MET 81  ? CE  ? A MET 81  CE  
24  1 Y 1 A SER 86  ? OG  ? A SER 86  OG  
25  1 Y 1 A ILE 87  ? CG1 ? A ILE 87  CG1 
26  1 Y 1 A ILE 87  ? CG2 ? A ILE 87  CG2 
27  1 Y 1 A ILE 87  ? CD1 ? A ILE 87  CD1 
28  1 Y 1 A ASP 89  ? CG  ? A ASP 89  CG  
29  1 Y 1 A ASP 89  ? OD1 ? A ASP 89  OD1 
30  1 Y 1 A ASP 89  ? OD2 ? A ASP 89  OD2 
31  1 Y 1 A THR 90  ? OG1 ? A THR 90  OG1 
32  1 Y 1 A THR 90  ? CG2 ? A THR 90  CG2 
33  1 Y 1 A VAL 91  ? CG1 ? A VAL 91  CG1 
34  1 Y 1 A VAL 91  ? CG2 ? A VAL 91  CG2 
35  1 Y 1 A GLU 93  ? CG  ? A GLU 93  CG  
36  1 Y 1 A GLU 93  ? CD  ? A GLU 93  CD  
37  1 Y 1 A GLU 93  ? OE1 ? A GLU 93  OE1 
38  1 Y 1 A GLU 93  ? OE2 ? A GLU 93  OE2 
39  1 Y 1 A SER 95  ? OG  ? A SER 95  OG  
40  1 Y 1 A GLU 96  ? CG  ? A GLU 96  CG  
41  1 Y 1 A GLU 96  ? CD  ? A GLU 96  CD  
42  1 Y 1 A GLU 96  ? OE1 ? A GLU 96  OE1 
43  1 Y 1 A GLU 96  ? OE2 ? A GLU 96  OE2 
44  1 Y 1 A TYR 97  ? CG  ? A TYR 97  CG  
45  1 Y 1 A TYR 97  ? CD1 ? A TYR 97  CD1 
46  1 Y 1 A TYR 97  ? CD2 ? A TYR 97  CD2 
47  1 Y 1 A TYR 97  ? CE1 ? A TYR 97  CE1 
48  1 Y 1 A TYR 97  ? CE2 ? A TYR 97  CE2 
49  1 Y 1 A TYR 97  ? CZ  ? A TYR 97  CZ  
50  1 Y 1 A TYR 97  ? OH  ? A TYR 97  OH  
51  1 Y 1 A SER 98  ? OG  ? A SER 98  OG  
52  1 Y 1 A LEU 99  ? CG  ? A LEU 99  CG  
53  1 Y 1 A LEU 99  ? CD1 ? A LEU 99  CD1 
54  1 Y 1 A LEU 99  ? CD2 ? A LEU 99  CD2 
55  1 Y 1 A THR 100 ? OG1 ? A THR 100 OG1 
56  1 Y 1 A THR 100 ? CG2 ? A THR 100 CG2 
57  1 Y 1 A VAL 101 ? CG1 ? A VAL 101 CG1 
58  1 Y 1 A VAL 101 ? CG2 ? A VAL 101 CG2 
59  1 Y 1 A ILE 103 ? CG1 ? A ILE 103 CG1 
60  1 Y 1 A ILE 103 ? CG2 ? A ILE 103 CG2 
61  1 Y 1 A ILE 103 ? CD1 ? A ILE 103 CD1 
62  1 Y 1 A VAL 107 ? CG1 ? A VAL 107 CG1 
63  1 Y 1 A VAL 107 ? CG2 ? A VAL 107 CG2 
64  1 Y 1 A SER 108 ? OG  ? A SER 108 OG  
65  1 Y 1 A GLN 109 ? CG  ? A GLN 109 CG  
66  1 Y 1 A GLN 109 ? CD  ? A GLN 109 CD  
67  1 Y 1 A GLN 109 ? OE1 ? A GLN 109 OE1 
68  1 Y 1 A GLN 109 ? NE2 ? A GLN 109 NE2 
69  1 Y 1 A PHE 111 ? CG  ? A PHE 111 CG  
70  1 Y 1 A PHE 111 ? CD1 ? A PHE 111 CD1 
71  1 Y 1 A PHE 111 ? CD2 ? A PHE 111 CD2 
72  1 Y 1 A PHE 111 ? CE1 ? A PHE 111 CE1 
73  1 Y 1 A PHE 111 ? CE2 ? A PHE 111 CE2 
74  1 Y 1 A PHE 111 ? CZ  ? A PHE 111 CZ  
75  1 Y 1 A GLN 112 ? CG  ? A GLN 112 CG  
76  1 Y 1 A GLN 112 ? CD  ? A GLN 112 CD  
77  1 Y 1 A GLN 112 ? OE1 ? A GLN 112 OE1 
78  1 Y 1 A GLN 112 ? NE2 ? A GLN 112 NE2 
79  1 Y 1 A TYR 113 ? CG  ? A TYR 113 CG  
80  1 Y 1 A TYR 113 ? CD1 ? A TYR 113 CD1 
81  1 Y 1 A TYR 113 ? CD2 ? A TYR 113 CD2 
82  1 Y 1 A TYR 113 ? CE1 ? A TYR 113 CE1 
83  1 Y 1 A TYR 113 ? CE2 ? A TYR 113 CE2 
84  1 Y 1 A TYR 113 ? CZ  ? A TYR 113 CZ  
85  1 Y 1 A TYR 113 ? OH  ? A TYR 113 OH  
86  1 Y 1 A THR 114 ? OG1 ? A THR 114 OG1 
87  1 Y 1 A THR 114 ? CG2 ? A THR 114 CG2 
88  1 Y 1 A LYS 116 ? CG  ? A LYS 116 CG  
89  1 Y 1 A LYS 116 ? CD  ? A LYS 116 CD  
90  1 Y 1 A LYS 116 ? CE  ? A LYS 116 CE  
91  1 Y 1 A LYS 116 ? NZ  ? A LYS 116 NZ  
92  1 Y 1 A GLU 117 ? CG  ? A GLU 117 CG  
93  1 Y 1 A GLU 117 ? CD  ? A GLU 117 CD  
94  1 Y 1 A GLU 117 ? OE1 ? A GLU 117 OE1 
95  1 Y 1 A GLU 117 ? OE2 ? A GLU 117 OE2 
96  1 Y 1 A ASN 118 ? CG  ? A ASN 118 CG  
97  1 Y 1 A ASN 118 ? OD1 ? A ASN 118 OD1 
98  1 Y 1 A ASN 118 ? ND2 ? A ASN 118 ND2 
99  1 Y 1 A ASP 119 ? CG  ? A ASP 119 CG  
100 1 Y 1 A ASP 119 ? OD1 ? A ASP 119 OD1 
101 1 Y 1 A ASP 119 ? OD2 ? A ASP 119 OD2 
102 1 Y 1 A THR 120 ? OG1 ? A THR 120 OG1 
103 1 Y 1 A THR 120 ? CG2 ? A THR 120 CG2 
104 1 Y 1 A ILE 123 ? CG1 ? A ILE 123 CG1 
105 1 Y 1 A ILE 123 ? CG2 ? A ILE 123 CG2 
106 1 Y 1 A ILE 123 ? CD1 ? A ILE 123 CD1 
107 1 Y 1 A GLU 127 ? CG  ? A GLU 127 CG  
108 1 Y 1 A GLU 127 ? CD  ? A GLU 127 CD  
109 1 Y 1 A GLU 127 ? OE1 ? A GLU 127 OE1 
110 1 Y 1 A GLU 127 ? OE2 ? A GLU 127 OE2 
111 1 Y 1 A LYS 129 ? CG  ? A LYS 129 CG  
112 1 Y 1 A LYS 129 ? CD  ? A LYS 129 CD  
113 1 Y 1 A LYS 129 ? CE  ? A LYS 129 CE  
114 1 Y 1 A LYS 129 ? NZ  ? A LYS 129 NZ  
115 1 Y 1 A THR 147 ? OG1 ? A THR 147 OG1 
116 1 Y 1 A THR 147 ? CG2 ? A THR 147 CG2 
117 1 Y 1 A THR 149 ? OG1 ? A THR 149 OG1 
118 1 Y 1 A THR 149 ? CG2 ? A THR 149 CG2 
119 1 Y 1 A SER 152 ? OG  ? A SER 152 OG  
120 1 Y 1 A LYS 159 ? CG  ? A LYS 159 CG  
121 1 Y 1 A LYS 159 ? CD  ? A LYS 159 CD  
122 1 Y 1 A LYS 159 ? CE  ? A LYS 159 CE  
123 1 Y 1 A LYS 159 ? NZ  ? A LYS 159 NZ  
124 1 Y 1 A ASP 162 ? CG  ? A ASP 162 CG  
125 1 Y 1 A ASP 162 ? OD1 ? A ASP 162 OD1 
126 1 Y 1 A ASP 162 ? OD2 ? A ASP 162 OD2 
127 1 Y 1 A ASN 163 ? CG  ? A ASN 163 CG  
128 1 Y 1 A ASN 163 ? OD1 ? A ASN 163 OD1 
129 1 Y 1 A ASN 163 ? ND2 ? A ASN 163 ND2 
130 1 Y 1 A ASP 164 ? CG  ? A ASP 164 CG  
131 1 Y 1 A ASP 164 ? OD1 ? A ASP 164 OD1 
132 1 Y 1 A ASP 164 ? OD2 ? A ASP 164 OD2 
133 1 Y 1 A ILE 171 ? CG1 ? A ILE 171 CG1 
134 1 Y 1 A ILE 171 ? CG2 ? A ILE 171 CG2 
135 1 Y 1 A ILE 171 ? CD1 ? A ILE 171 CD1 
136 1 Y 1 A THR 172 ? OG1 ? A THR 172 OG1 
137 1 Y 1 A THR 172 ? CG2 ? A THR 172 CG2 
138 1 Y 1 A THR 175 ? OG1 ? A THR 175 OG1 
139 1 Y 1 A THR 175 ? CG2 ? A THR 175 CG2 
140 1 Y 1 A SER 176 ? OG  ? A SER 176 OG  
141 1 Y 1 A SER 243 ? OG  ? A SER 243 OG  
142 1 Y 1 A THR 245 ? OG1 ? A THR 245 OG1 
143 1 Y 1 A THR 245 ? CG2 ? A THR 245 CG2 
144 1 Y 1 A PHE 269 ? CG  ? A PHE 269 CG  
145 1 Y 1 A PHE 269 ? CD1 ? A PHE 269 CD1 
146 1 Y 1 A PHE 269 ? CD2 ? A PHE 269 CD2 
147 1 Y 1 A PHE 269 ? CE1 ? A PHE 269 CE1 
148 1 Y 1 A PHE 269 ? CE2 ? A PHE 269 CE2 
149 1 Y 1 A PHE 269 ? CZ  ? A PHE 269 CZ  
150 1 Y 1 A GLU 356 ? CG  ? A GLU 356 CG  
151 1 Y 1 A GLU 356 ? CD  ? A GLU 356 CD  
152 1 Y 1 A GLU 356 ? OE1 ? A GLU 356 OE1 
153 1 Y 1 A GLU 356 ? OE2 ? A GLU 356 OE2 
154 1 Y 1 B MET 74  ? CG  ? B MET 74  CG  
155 1 Y 1 B MET 74  ? SD  ? B MET 74  SD  
156 1 Y 1 B MET 74  ? CE  ? B MET 74  CE  
157 1 Y 1 B GLU 86  ? CG  ? B GLU 86  CG  
158 1 Y 1 B GLU 86  ? CD  ? B GLU 86  CD  
159 1 Y 1 B GLU 86  ? OE1 ? B GLU 86  OE1 
160 1 Y 1 B GLU 86  ? OE2 ? B GLU 86  OE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9C3B 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9C3B 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9C3B 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9C3B 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.006 ? 4423 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.664 ? 6030 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.428 ? 625  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.044 ? 719  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 780  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9C3B 
_struct.title                        'Structure of the Shigella flexneri bacteriophage Sf14 - tail helical' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9C3B 
_struct_keywords.text            'Sf14, VIRUS' 
_struct_keywords.pdbx_keywords   VIRUS 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP A0A2K9VKE4_9CAUD A0A2K9VKE4 ? 1 
;MWNPIVNVDITLNTAGTTREGFGLPLFLASTDNFEERIRGYTSLTEVAEDFDESTAAYKAAKQLWSQTPKVTQLYIGRRT
MQYTVSIPDTVAEGSEYSLTVAIGGGVSQPFQYTAKENDTALIVLNEFKSQIEASPTIKDGVNASVTGTGASATMIITKA
GDNDFVKVTSITPTTSIAATTADTASAALASIETYSTDWYFISAEDRTQQFVLAMASEIQARKKIFFTANADVKALQGTD
LTSATDVPAQLAKSKYTRTVCLWHHTAEFDYPEMAYIAYGAPYDAGSIAWGNAQLTGVAASLQPANQRPLISIQKSALDT
RSCNFIDLDGGVPVVRRGITSGGEWIDIVRGVDWLESDLKTSLRDLLINQKGGKITYDDTGITRIRQVIETSLQRAVNRK
FLSTYTVTVPKASQVALADKKARILKDITFHGILAGAILDVDLKGTVAYE
;
1 
2 UNP A0A2K9VK99_9CAUD A0A2K9VK99 ? 2 
;MAMYQQYSPKDVVCSWNGIAIEGFAPDSFLRLQRTSPLVTPVVGAGGQVALTRNADKTGTIEIELMQTSLSNQMLSAIQA
KQDDMELEEDISSNFVIYDPSGSVLATGINAWLQELPQIELGRDQNSKTWIFGCEKLDYTSTIPASSV
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9C3B A 1 ? 450 ? A0A2K9VKE4 1 ? 450 ? 1 450 
2 2 9C3B B 1 ? 148 ? A0A2K9VK99 1 ? 148 ? 1 148 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 43  ? PHE A 51  ? SER A 43  PHE A 51  1 ? 9  
HELX_P HELX_P2  AA2 THR A 55  ? TRP A 65  ? THR A 55  TRP A 65  1 ? 11 
HELX_P HELX_P3  AA3 ILE A 103 ? VAL A 107 ? ILE A 103 VAL A 107 5 ? 5  
HELX_P HELX_P4  AA4 THR A 120 ? SER A 135 ? THR A 120 SER A 135 1 ? 16 
HELX_P HELX_P5  AA5 THR A 149 ? ALA A 153 ? THR A 149 ALA A 153 5 ? 5  
HELX_P HELX_P6  AA6 THR A 184 ? SER A 196 ? THR A 184 SER A 196 1 ? 13 
HELX_P HELX_P7  AA7 THR A 208 ? ALA A 221 ? THR A 208 ALA A 221 1 ? 14 
HELX_P HELX_P8  AA8 VAL A 233 ? GLY A 238 ? VAL A 233 GLY A 238 1 ? 6  
HELX_P HELX_P9  AA9 ASP A 246 ? LYS A 255 ? ASP A 246 LYS A 255 1 ? 10 
HELX_P HELX_P10 AB1 PRO A 272 ? ALA A 281 ? PRO A 272 ALA A 281 1 ? 10 
HELX_P HELX_P11 AB2 ILE A 311 ? ARG A 321 ? ILE A 311 ARG A 321 1 ? 11 
HELX_P HELX_P12 AB3 TRP A 345 ? ASN A 369 ? TRP A 345 ASN A 369 1 ? 25 
HELX_P HELX_P13 AB4 ASP A 378 ? ARG A 399 ? ASP A 378 ARG A 399 1 ? 22 
HELX_P HELX_P14 AB5 LYS A 411 ? VAL A 415 ? LYS A 411 VAL A 415 5 ? 5  
HELX_P HELX_P15 AB6 ALA A 416 ? ALA A 422 ? ALA A 416 ALA A 422 1 ? 7  
HELX_P HELX_P16 AB7 SER B 8   ? VAL B 12  ? SER B 8   VAL B 12  5 ? 5  
HELX_P HELX_P17 AB8 LEU B 70  ? MET B 85  ? LEU B 70  MET B 85  1 ? 16 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 9 ? 
AA2 ? 4 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
AA5 ? 4 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA1 6 7 ? parallel      
AA1 7 8 ? anti-parallel 
AA1 8 9 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 38  ? TYR A 41  ? ILE A 38  TYR A 41  
AA1 2 LEU A 74  ? GLY A 77  ? LEU A 74  GLY A 77  
AA1 3 PRO A 25  ? LEU A 28  ? PRO A 25  LEU A 28  
AA1 4 PHE A 201 ? ALA A 204 ? PHE A 201 ALA A 204 
AA1 5 ILE A 225 ? ASN A 230 ? ILE A 225 ASN A 230 
AA1 6 THR A 259 ? TRP A 263 ? THR A 259 TRP A 263 
AA1 7 ASN A 324 ? ASP A 329 ? ASN A 324 ASP A 329 
AA1 8 VAL A 332 ? ARG A 336 ? VAL A 332 ARG A 336 
AA1 9 ALA A 293 ? GLN A 294 ? ALA A 293 GLN A 294 
AA2 1 VAL A 142 ? VAL A 146 ? VAL A 142 VAL A 146 
AA2 2 MET A 155 ? LYS A 159 ? MET A 155 LYS A 159 
AA2 3 MET A 81  ? VAL A 85  ? MET A 81  VAL A 85  
AA2 4 THR A 180 ? THR A 181 ? THR A 180 THR A 181 
AA3 1 LEU A 402 ? THR A 408 ? LEU A 402 THR A 408 
AA3 2 THR A 429 ? LEU A 434 ? THR A 429 LEU A 434 
AA4 1 ILE B 19  ? ILE B 21  ? ILE B 19  ILE B 21  
AA4 2 VAL B 13  ? TRP B 16  ? VAL B 13  TRP B 16  
AA4 3 SER B 93  ? TYR B 98  ? SER B 93  TYR B 98  
AA4 4 ALA B 106 ? ALA B 111 ? ALA B 106 ALA B 111 
AA4 5 LYS B 136 ? TYR B 139 ? LYS B 136 TYR B 139 
AA5 1 LEU B 30  ? ARG B 34  ? LEU B 30  ARG B 34  
AA5 2 GLY B 59  ? LEU B 65  ? GLY B 59  LEU B 65  
AA5 3 LYS B 128 ? GLY B 133 ? LYS B 128 GLY B 133 
AA5 4 LEU B 113 ? GLU B 115 ? LEU B 113 GLU B 115 
AA6 1 VAL B 42  ? VAL B 43  ? VAL B 42  VAL B 43  
AA6 2 VAL B 49  ? ALA B 50  ? VAL B 49  ALA B 50  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N TYR A 41  ? N TYR A 41  O LEU A 74  ? O LEU A 74  
AA1 2 3 O GLY A 77  ? O GLY A 77  N PHE A 27  ? N PHE A 27  
AA1 3 4 N LEU A 26  ? N LEU A 26  O PHE A 201 ? O PHE A 201 
AA1 4 5 N ILE A 202 ? N ILE A 202 O PHE A 227 ? O PHE A 227 
AA1 5 6 N THR A 228 ? N THR A 228 O VAL A 260 ? O VAL A 260 
AA1 6 7 N TRP A 263 ? N TRP A 263 O ASN A 324 ? O ASN A 324 
AA1 7 8 N ASP A 327 ? N ASP A 327 O VAL A 334 ? O VAL A 334 
AA1 8 9 O VAL A 335 ? O VAL A 335 N ALA A 293 ? N ALA A 293 
AA2 1 2 N ASN A 143 ? N ASN A 143 O THR A 158 ? O THR A 158 
AA2 2 3 O MET A 155 ? O MET A 155 N VAL A 85  ? N VAL A 85  
AA2 3 4 N GLN A 82  ? N GLN A 82  O THR A 180 ? O THR A 180 
AA3 1 2 N SER A 403 ? N SER A 403 O ILE A 433 ? O ILE A 433 
AA4 1 2 O ILE B 21  ? O ILE B 21  N CYS B 14  ? N CYS B 14  
AA4 2 3 N VAL B 13  ? N VAL B 13  O TYR B 98  ? O TYR B 98  
AA4 3 4 N PHE B 95  ? N PHE B 95  O GLY B 108 ? O GLY B 108 
AA4 4 5 N THR B 107 ? N THR B 107 O ASP B 138 ? O ASP B 138 
AA5 1 2 N ARG B 31  ? N ARG B 31  O GLU B 62  ? O GLU B 62  
AA5 2 3 N ILE B 61  ? N ILE B 61  O PHE B 132 ? O PHE B 132 
AA5 3 4 O ILE B 131 ? O ILE B 131 N GLN B 114 ? N GLN B 114 
AA6 1 2 N VAL B 42  ? N VAL B 42  O ALA B 50  ? O ALA B 50  
# 
_pdbx_entry_details.entry_id                   9C3B 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 N  A PRO 88  ? ? CA A PRO 88  ? ? CB A PRO 88  ? ? 94.60 103.30 -8.70  1.20 N 
2 1 CA A PRO 136 ? ? N  A PRO 136 ? ? CD A PRO 136 ? ? 97.55 111.70 -14.15 1.40 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 12  ? ? -97.79  34.84   
2  1 ALA A 29  ? ? -96.69  -157.92 
3  1 SER A 30  ? ? -144.88 33.29   
4  1 ASP A 32  ? ? -98.21  32.85   
5  1 TRP A 65  ? ? -95.48  31.08   
6  1 VAL A 71  ? ? 65.14   108.37  
7  1 ILE A 87  ? ? -132.75 -31.49  
8  1 PRO A 88  ? ? 12.30   69.81   
9  1 ASP A 89  ? ? -174.53 -61.92  
10 1 THR A 90  ? ? 51.30   79.52   
11 1 ALA A 92  ? ? 46.94   -140.09 
12 1 SER A 95  ? ? -131.96 -45.95  
13 1 GLU A 96  ? ? 27.68   68.87   
14 1 TYR A 97  ? ? -168.28 -146.53 
15 1 ILE A 103 ? ? 64.85   165.12  
16 1 GLN A 109 ? ? 36.67   68.74   
17 1 ALA A 115 ? ? -160.59 -166.64 
18 1 LYS A 116 ? ? -168.44 -150.06 
19 1 GLU A 117 ? ? 53.91   79.98   
20 1 THR A 172 ? ? 69.42   146.11  
21 1 LYS A 223 ? ? -103.96 40.59   
22 1 ALA A 231 ? ? -141.30 42.70   
23 1 THR A 266 ? ? -92.69  51.95   
24 1 GLU A 268 ? ? 37.18   -72.40  
25 1 SER A 301 ? ? -69.74  92.89   
26 1 ARG A 337 ? ? 75.47   -11.23  
27 1 ARG A 423 ? ? 39.34   53.02   
28 1 ASP A 427 ? ? 37.11   46.03   
29 1 VAL A 447 ? ? 52.37   93.98   
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 308 ? ? 0.263 'SIDE CHAIN' 
2 1 ARG B 53  ? ? 0.087 'SIDE CHAIN' 
3 1 ARG B 123 ? ? 0.144 'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9C3B 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9C3B 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.4 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               23422 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               HELICAL 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               NATURAL 
_em_entity_assembly.type                 VIRUS 
_em_entity_assembly.name                 'Shigella phage Sf14' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        9C3B 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             500 
_em_imaging.nominal_defocus_max             3500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_virus_entity.id                    1 
_em_virus_entity.virus_host_category   ? 
_em_virus_entity.virus_type            VIRION 
_em_virus_entity.virus_isolate         OTHER 
_em_virus_entity.entity_assembly_id    1 
_em_virus_entity.enveloped             NO 
_em_virus_entity.empty                 NO 
_em_virus_entity.details               ? 
# 
_em_vitrification.entry_id              9C3B 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277.15 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9C3B 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   HELICAL 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A TRP 2   ? A TRP 2   
3  1 Y 1 A ASN 3   ? A ASN 3   
4  1 Y 1 A TYR 449 ? A TYR 449 
5  1 Y 1 A GLU 450 ? A GLU 450 
6  1 Y 1 B MET 1   ? B MET 1   
7  1 Y 1 B ALA 145 ? B ALA 145 
8  1 Y 1 B SER 146 ? B SER 146 
9  1 Y 1 B SER 147 ? B SER 147 
10 1 Y 1 B VAL 148 ? B VAL 148 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-31 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9C3B 
_em_admin.last_update        2025-02-05 
_em_admin.map_release_date   2025-02-05 
_em_admin.title              'Structure of the Shigella flexneri bacteriophage Sf14 - tail helical' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 10 mM Tris  1 'tris(hydroxymethyl)aminomethane' 
1 10 mM MgCl2 2 'magnesium chloride'              
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          2024304 
_em_entity_assembly_naturalsource.organism             'Shigella phage Sf14' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_helical_entity.id                             1 
_em_helical_entity.image_processing_id            1 
_em_helical_entity.details                        ? 
_em_helical_entity.axial_symmetry                 C6 
_em_helical_entity.angular_rotation_per_subunit   25.75 
_em_helical_entity.axial_rise_per_subunit         37.062 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         33 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'             ? 2  1 1 1 ?      ?            
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?            
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?            
CLASSIFICATION                  ? 5  1 1 1 ?      ?            
MASKING                         ? 6  1 1 1 ?      ?            
RECONSTRUCTION                  ? 7  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?            
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?            
'CTF CORRECTION'                ? 10 1 1 1 ?      ?            
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?            
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?            
'MODEL FITTING'                 ? 13 1 1 1 ?      ?            
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?            
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?            
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?            
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?            
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?            
OTHER                           ? 19 1 1 1 ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_em_virus_natural_host.entity_assembly_id   1 
_em_virus_natural_host.id                   1 
_em_virus_natural_host.ncbi_tax_id          424720 
_em_virus_natural_host.organism             'Shigella flexneri Y' 
_em_virus_natural_host.strain               ? 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' R01AI170608 1 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)'        'United States' U24GM116789 2 
# 
_atom_sites.entry_id                    9C3B 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . PRO A 1 4   ? 56.898  -25.251 -165.077 1.00 76.33  ? 4   PRO A N   1 
ATOM 2    C CA  . PRO A 1 4   ? 56.420  -24.475 -166.214 1.00 73.49  ? 4   PRO A CA  1 
ATOM 3    C C   . PRO A 1 4   ? 55.138  -23.758 -165.842 1.00 78.26  ? 4   PRO A C   1 
ATOM 4    O O   . PRO A 1 4   ? 54.224  -24.434 -165.346 1.00 82.62  ? 4   PRO A O   1 
ATOM 5    C CB  . PRO A 1 4   ? 56.200  -25.488 -167.324 1.00 64.38  ? 4   PRO A CB  1 
ATOM 6    C CG  . PRO A 1 4   ? 56.297  -26.822 -166.633 1.00 72.97  ? 4   PRO A CG  1 
ATOM 7    C CD  . PRO A 1 4   ? 57.262  -26.587 -165.487 1.00 73.00  ? 4   PRO A CD  1 
ATOM 8    N N   . ILE A 1 5   ? 55.046  -22.447 -166.089 1.00 77.16  ? 5   ILE A N   1 
ATOM 9    C CA  . ILE A 1 5   ? 53.862  -21.648 -165.643 1.00 74.63  ? 5   ILE A CA  1 
ATOM 10   C C   . ILE A 1 5   ? 52.584  -22.488 -165.760 1.00 75.28  ? 5   ILE A C   1 
ATOM 11   O O   . ILE A 1 5   ? 51.898  -22.634 -164.737 1.00 75.12  ? 5   ILE A O   1 
ATOM 12   C CB  . ILE A 1 5   ? 53.747  -20.342 -166.441 1.00 67.67  ? 5   ILE A CB  1 
ATOM 13   C CG1 . ILE A 1 5   ? 54.940  -19.432 -166.197 1.00 72.65  ? 5   ILE A CG1 1 
ATOM 14   C CG2 . ILE A 1 5   ? 52.432  -19.632 -166.131 1.00 67.23  ? 5   ILE A CG2 1 
ATOM 15   C CD1 . ILE A 1 5   ? 54.590  -17.955 -166.210 1.00 71.44  ? 5   ILE A CD1 1 
ATOM 16   N N   . VAL A 1 6   ? 52.286  -23.016 -166.946 1.00 74.80  ? 6   VAL A N   1 
ATOM 17   C CA  . VAL A 1 6   ? 51.087  -23.877 -167.143 1.00 73.10  ? 6   VAL A CA  1 
ATOM 18   C C   . VAL A 1 6   ? 51.503  -25.252 -167.687 1.00 76.52  ? 6   VAL A C   1 
ATOM 19   O O   . VAL A 1 6   ? 51.921  -25.311 -168.854 1.00 85.72  ? 6   VAL A O   1 
ATOM 20   C CB  . VAL A 1 6   ? 50.173  -23.144 -168.128 1.00 66.92  ? 6   VAL A CB  1 
ATOM 21   C CG1 . VAL A 1 6   ? 49.085  -22.367 -167.403 1.00 75.45  ? 6   VAL A CG1 1 
ATOM 22   C CG2 . VAL A 1 6   ? 50.960  -22.223 -169.049 1.00 66.99  ? 6   VAL A CG2 1 
ATOM 23   N N   . ASN A 1 7   ? 51.379  -26.315 -166.886 1.00 78.45  ? 7   ASN A N   1 
ATOM 24   C CA  . ASN A 1 7   ? 51.777  -27.642 -167.335 1.00 77.14  ? 7   ASN A CA  1 
ATOM 25   C C   . ASN A 1 7   ? 50.541  -28.337 -167.882 1.00 85.86  ? 7   ASN A C   1 
ATOM 26   O O   . ASN A 1 7   ? 49.667  -28.754 -167.115 1.00 89.60  ? 7   ASN A O   1 
ATOM 27   C CB  . ASN A 1 7   ? 52.406  -28.439 -166.198 1.00 75.85  ? 7   ASN A CB  1 
ATOM 28   C CG  . ASN A 1 7   ? 53.098  -29.684 -166.684 1.00 81.84  ? 7   ASN A CG  1 
ATOM 29   O OD1 . ASN A 1 7   ? 53.204  -29.914 -167.886 1.00 83.74  ? 7   ASN A OD1 1 
ATOM 30   N ND2 . ASN A 1 7   ? 53.577  -30.497 -165.754 1.00 84.58  ? 7   ASN A ND2 1 
ATOM 31   N N   . VAL A 1 8   ? 50.472  -28.465 -169.203 1.00 85.02  ? 8   VAL A N   1 
ATOM 32   C CA  . VAL A 1 8   ? 49.303  -28.993 -169.888 1.00 81.92  ? 8   VAL A CA  1 
ATOM 33   C C   . VAL A 1 8   ? 49.673  -30.326 -170.515 1.00 83.14  ? 8   VAL A C   1 
ATOM 34   O O   . VAL A 1 8   ? 50.676  -30.422 -171.230 1.00 86.11  ? 8   VAL A O   1 
ATOM 35   C CB  . VAL A 1 8   ? 48.785  -28.016 -170.955 1.00 78.98  ? 8   VAL A CB  1 
ATOM 36   C CG1 . VAL A 1 8   ? 47.575  -28.595 -171.651 1.00 80.37  ? 8   VAL A CG1 1 
ATOM 37   C CG2 . VAL A 1 8   ? 48.450  -26.687 -170.324 1.00 82.83  ? 8   VAL A CG2 1 
ATOM 38   N N   . ASP A 1 9   ? 48.869  -31.348 -170.243 1.00 93.57  ? 9   ASP A N   1 
ATOM 39   C CA  . ASP A 1 9   ? 49.075  -32.680 -170.794 1.00 95.23  ? 9   ASP A CA  1 
ATOM 40   C C   . ASP A 1 9   ? 47.762  -33.108 -171.429 1.00 99.98  ? 9   ASP A C   1 
ATOM 41   O O   . ASP A 1 9   ? 46.712  -33.051 -170.784 1.00 99.02  ? 9   ASP A O   1 
ATOM 42   C CB  . ASP A 1 9   ? 49.516  -33.658 -169.701 1.00 97.83  ? 9   ASP A CB  1 
ATOM 43   C CG  . ASP A 1 9   ? 49.367  -35.122 -170.101 1.00 106.47 ? 9   ASP A CG  1 
ATOM 44   O OD1 . ASP A 1 9   ? 49.138  -35.429 -171.289 1.00 106.80 ? 9   ASP A OD1 1 
ATOM 45   O OD2 . ASP A 1 9   ? 49.553  -35.985 -169.218 1.00 109.29 ? 9   ASP A OD2 1 
ATOM 46   N N   . ILE A 1 10  ? 47.823  -33.538 -172.685 1.00 85.47  ? 10  ILE A N   1 
ATOM 47   C CA  . ILE A 1 10  ? 46.649  -33.966 -173.434 1.00 79.54  ? 10  ILE A CA  1 
ATOM 48   C C   . ILE A 1 10  ? 46.865  -35.405 -173.867 1.00 80.36  ? 10  ILE A C   1 
ATOM 49   O O   . ILE A 1 10  ? 47.845  -35.709 -174.558 1.00 85.49  ? 10  ILE A O   1 
ATOM 50   C CB  . ILE A 1 10  ? 46.390  -33.065 -174.649 1.00 79.19  ? 10  ILE A CB  1 
ATOM 51   C CG1 . ILE A 1 10  ? 45.983  -31.666 -174.197 1.00 86.01  ? 10  ILE A CG1 1 
ATOM 52   C CG2 . ILE A 1 10  ? 45.331  -33.672 -175.537 1.00 78.04  ? 10  ILE A CG2 1 
ATOM 53   C CD1 . ILE A 1 10  ? 44.568  -31.580 -173.691 1.00 86.00  ? 10  ILE A CD1 1 
ATOM 54   N N   . THR A 1 11  ? 45.953  -36.284 -173.477 1.00 89.23  ? 11  THR A N   1 
ATOM 55   C CA  . THR A 1 11  ? 46.009  -37.689 -173.840 1.00 89.93  ? 11  THR A CA  1 
ATOM 56   C C   . THR A 1 11  ? 44.773  -38.067 -174.642 1.00 94.97  ? 11  THR A C   1 
ATOM 57   O O   . THR A 1 11  ? 43.727  -37.419 -174.556 1.00 99.13  ? 11  THR A O   1 
ATOM 58   C CB  . THR A 1 11  ? 46.113  -38.579 -172.599 1.00 91.35  ? 11  THR A CB  1 
ATOM 59   O OG1 . THR A 1 11  ? 45.017  -38.304 -171.723 1.00 98.94  ? 11  THR A OG1 1 
ATOM 60   C CG2 . THR A 1 11  ? 47.408  -38.309 -171.865 1.00 90.89  ? 11  THR A CG2 1 
ATOM 61   N N   . LEU A 1 12  ? 44.903  -39.135 -175.423 1.00 78.88  ? 12  LEU A N   1 
ATOM 62   C CA  . LEU A 1 12  ? 43.836  -39.597 -176.307 1.00 81.47  ? 12  LEU A CA  1 
ATOM 63   C C   . LEU A 1 12  ? 43.032  -40.731 -175.688 1.00 81.11  ? 12  LEU A C   1 
ATOM 64   O O   . LEU A 1 12  ? 42.575  -41.637 -176.386 1.00 82.03  ? 12  LEU A O   1 
ATOM 65   C CB  . LEU A 1 12  ? 44.415  -40.022 -177.649 1.00 79.33  ? 12  LEU A CB  1 
ATOM 66   C CG  . LEU A 1 12  ? 45.145  -38.911 -178.395 1.00 77.07  ? 12  LEU A CG  1 
ATOM 67   C CD1 . LEU A 1 12  ? 45.902  -39.472 -179.580 1.00 80.02  ? 12  LEU A CD1 1 
ATOM 68   C CD2 . LEU A 1 12  ? 44.160  -37.854 -178.842 1.00 79.98  ? 12  LEU A CD2 1 
ATOM 69   N N   . ASN A 1 13  ? 42.843  -40.701 -174.376 1.00 96.95  ? 13  ASN A N   1 
ATOM 70   C CA  . ASN A 1 13  ? 42.087  -41.719 -173.666 1.00 98.57  ? 13  ASN A CA  1 
ATOM 71   C C   . ASN A 1 13  ? 40.759  -41.144 -173.199 1.00 100.04 ? 13  ASN A C   1 
ATOM 72   O O   . ASN A 1 13  ? 40.695  -40.002 -172.737 1.00 106.17 ? 13  ASN A O   1 
ATOM 73   C CB  . ASN A 1 13  ? 42.873  -42.249 -172.467 1.00 102.24 ? 13  ASN A CB  1 
ATOM 74   C CG  . ASN A 1 13  ? 43.216  -43.715 -172.598 1.00 105.94 ? 13  ASN A CG  1 
ATOM 75   O OD1 . ASN A 1 13  ? 42.945  -44.338 -173.625 1.00 106.59 ? 13  ASN A OD1 1 
ATOM 76   N ND2 . ASN A 1 13  ? 43.811  -44.279 -171.555 1.00 107.42 ? 13  ASN A ND2 1 
ATOM 77   N N   . THR A 1 14  ? 39.702  -41.941 -173.321 1.00 100.90 ? 14  THR A N   1 
ATOM 78   C CA  . THR A 1 14  ? 38.383  -41.502 -172.897 1.00 102.18 ? 14  THR A CA  1 
ATOM 79   C C   . THR A 1 14  ? 38.336  -41.308 -171.387 1.00 101.67 ? 14  THR A C   1 
ATOM 80   O O   . THR A 1 14  ? 39.047  -41.973 -170.628 1.00 98.80  ? 14  THR A O   1 
ATOM 81   C CB  . THR A 1 14  ? 37.324  -42.515 -173.320 1.00 104.15 ? 14  THR A CB  1 
ATOM 82   O OG1 . THR A 1 14  ? 37.729  -43.825 -172.908 1.00 106.62 ? 14  THR A OG1 1 
ATOM 83   C CG2 . THR A 1 14  ? 37.151  -42.500 -174.825 1.00 105.71 ? 14  THR A CG2 1 
ATOM 84   N N   . ALA A 1 15  ? 37.488  -40.383 -170.955 1.00 115.75 ? 15  ALA A N   1 
ATOM 85   C CA  . ALA A 1 15  ? 37.362  -40.048 -169.545 1.00 118.35 ? 15  ALA A CA  1 
ATOM 86   C C   . ALA A 1 15  ? 36.428  -41.023 -168.842 1.00 116.54 ? 15  ALA A C   1 
ATOM 87   O O   . ALA A 1 15  ? 35.380  -41.394 -169.375 1.00 116.49 ? 15  ALA A O   1 
ATOM 88   C CB  . ALA A 1 15  ? 36.846  -38.619 -169.375 1.00 117.02 ? 15  ALA A CB  1 
ATOM 89   N N   . GLY A 1 16  ? 36.818  -41.430 -167.640 1.00 115.38 ? 16  GLY A N   1 
ATOM 90   C CA  . GLY A 1 16  ? 36.007  -42.309 -166.822 1.00 114.88 ? 16  GLY A CA  1 
ATOM 91   C C   . GLY A 1 16  ? 35.613  -41.620 -165.531 1.00 117.87 ? 16  GLY A C   1 
ATOM 92   O O   . GLY A 1 16  ? 36.356  -40.799 -164.994 1.00 120.40 ? 16  GLY A O   1 
ATOM 93   N N   . THR A 1 17  ? 34.431  -41.965 -165.033 1.00 112.06 ? 17  THR A N   1 
ATOM 94   C CA  . THR A 1 17  ? 33.881  -41.359 -163.830 1.00 109.89 ? 17  THR A CA  1 
ATOM 95   C C   . THR A 1 17  ? 33.967  -42.344 -162.674 1.00 108.77 ? 17  THR A C   1 
ATOM 96   O O   . THR A 1 17  ? 33.606  -43.515 -162.822 1.00 113.41 ? 17  THR A O   1 
ATOM 97   C CB  . THR A 1 17  ? 32.430  -40.939 -164.048 1.00 110.96 ? 17  THR A CB  1 
ATOM 98   O OG1 . THR A 1 17  ? 31.578  -42.077 -163.873 1.00 111.57 ? 17  THR A OG1 1 
ATOM 99   C CG2 . THR A 1 17  ? 32.245  -40.392 -165.451 1.00 110.70 ? 17  THR A CG2 1 
ATOM 100  N N   . THR A 1 18  ? 34.439  -41.865 -161.529 1.00 96.00  ? 18  THR A N   1 
ATOM 101  C CA  . THR A 1 18  ? 34.567  -42.671 -160.325 1.00 95.78  ? 18  THR A CA  1 
ATOM 102  C C   . THR A 1 18  ? 33.632  -42.118 -159.261 1.00 96.07  ? 18  THR A C   1 
ATOM 103  O O   . THR A 1 18  ? 33.646  -40.915 -158.987 1.00 103.36 ? 18  THR A O   1 
ATOM 104  C CB  . THR A 1 18  ? 36.009  -42.668 -159.816 1.00 101.44 ? 18  THR A CB  1 
ATOM 105  O OG1 . THR A 1 18  ? 36.797  -43.560 -160.610 1.00 103.24 ? 18  THR A OG1 1 
ATOM 106  C CG2 . THR A 1 18  ? 36.063  -43.110 -158.371 1.00 101.57 ? 18  THR A CG2 1 
ATOM 107  N N   . ARG A 1 19  ? 32.823  -42.989 -158.668 1.00 79.09  ? 19  ARG A N   1 
ATOM 108  C CA  . ARG A 1 19  ? 31.881  -42.593 -157.636 1.00 79.93  ? 19  ARG A CA  1 
ATOM 109  C C   . ARG A 1 19  ? 32.118  -43.402 -156.370 1.00 84.33  ? 19  ARG A C   1 
ATOM 110  O O   . ARG A 1 19  ? 32.528  -44.563 -156.423 1.00 91.17  ? 19  ARG A O   1 
ATOM 111  C CB  . ARG A 1 19  ? 30.437  -42.779 -158.099 1.00 77.00  ? 19  ARG A CB  1 
ATOM 112  C CG  . ARG A 1 19  ? 29.442  -41.943 -157.327 1.00 76.10  ? 19  ARG A CG  1 
ATOM 113  C CD  . ARG A 1 19  ? 28.100  -41.890 -158.026 1.00 79.08  ? 19  ARG A CD  1 
ATOM 114  N NE  . ARG A 1 19  ? 27.135  -41.084 -157.290 1.00 79.87  ? 19  ARG A NE  1 
ATOM 115  C CZ  . ARG A 1 19  ? 26.626  -41.411 -156.111 1.00 80.72  ? 19  ARG A CZ  1 
ATOM 116  N NH1 . ARG A 1 19  ? 26.954  -42.538 -155.504 1.00 82.18  ? 19  ARG A NH1 1 
ATOM 117  N NH2 . ARG A 1 19  ? 25.762  -40.588 -155.527 1.00 83.76  ? 19  ARG A NH2 1 
ATOM 118  N N   . GLU A 1 20  ? 31.856  -42.765 -155.227 1.00 86.69  ? 20  GLU A N   1 
ATOM 119  C CA  . GLU A 1 20  ? 32.058  -43.429 -153.922 1.00 86.09  ? 20  GLU A CA  1 
ATOM 120  C C   . GLU A 1 20  ? 30.707  -43.776 -153.320 1.00 92.07  ? 20  GLU A C   1 
ATOM 121  O O   . GLU A 1 20  ? 29.896  -42.856 -153.123 1.00 97.68  ? 20  GLU A O   1 
ATOM 122  C CB  . GLU A 1 20  ? 32.809  -42.519 -152.997 1.00 30.00  ? 20  GLU A CB  1 
ATOM 123  N N   . GLY A 1 21  ? 30.487  -45.047 -153.017 1.00 76.47  ? 21  GLY A N   1 
ATOM 124  C CA  . GLY A 1 21  ? 29.231  -45.524 -152.474 1.00 72.51  ? 21  GLY A CA  1 
ATOM 125  C C   . GLY A 1 21  ? 29.406  -46.057 -151.072 1.00 74.09  ? 21  GLY A C   1 
ATOM 126  O O   . GLY A 1 21  ? 30.203  -45.517 -150.302 1.00 80.13  ? 21  GLY A O   1 
ATOM 127  N N   . PHE A 1 22  ? 28.669  -47.102 -150.720 1.00 57.22  ? 22  PHE A N   1 
ATOM 128  C CA  . PHE A 1 22  ? 28.816  -47.751 -149.424 1.00 58.13  ? 22  PHE A CA  1 
ATOM 129  C C   . PHE A 1 22  ? 29.393  -49.143 -149.640 1.00 67.25  ? 22  PHE A C   1 
ATOM 130  O O   . PHE A 1 22  ? 28.797  -49.968 -150.338 1.00 73.10  ? 22  PHE A O   1 
ATOM 131  C CB  . PHE A 1 22  ? 27.483  -47.826 -148.690 1.00 58.63  ? 22  PHE A CB  1 
ATOM 132  C CG  . PHE A 1 22  ? 27.555  -48.576 -147.400 1.00 61.58  ? 22  PHE A CG  1 
ATOM 133  C CD1 . PHE A 1 22  ? 28.263  -48.068 -146.333 1.00 65.74  ? 22  PHE A CD1 1 
ATOM 134  C CD2 . PHE A 1 22  ? 26.917  -49.786 -147.251 1.00 57.53  ? 22  PHE A CD2 1 
ATOM 135  C CE1 . PHE A 1 22  ? 28.334  -48.753 -145.144 1.00 61.18  ? 22  PHE A CE1 1 
ATOM 136  C CE2 . PHE A 1 22  ? 26.984  -50.473 -146.062 1.00 57.03  ? 22  PHE A CE2 1 
ATOM 137  C CZ  . PHE A 1 22  ? 27.694  -49.955 -145.010 1.00 55.04  ? 22  PHE A CZ  1 
ATOM 138  N N   . GLY A 1 23  ? 30.541  -49.401 -149.046 1.00 75.21  ? 23  GLY A N   1 
ATOM 139  C CA  . GLY A 1 23  ? 31.127  -50.721 -149.100 1.00 69.75  ? 23  GLY A CA  1 
ATOM 140  C C   . GLY A 1 23  ? 32.049  -50.880 -150.293 1.00 67.58  ? 23  GLY A C   1 
ATOM 141  O O   . GLY A 1 23  ? 31.901  -50.213 -151.325 1.00 74.45  ? 23  GLY A O   1 
ATOM 142  N N   . LEU A 1 24  ? 33.019  -51.778 -150.151 1.00 63.15  ? 24  LEU A N   1 
ATOM 143  C CA  . LEU A 1 24  ? 33.957  -52.087 -151.212 1.00 61.37  ? 24  LEU A CA  1 
ATOM 144  C C   . LEU A 1 24  ? 34.005  -53.592 -151.423 1.00 61.60  ? 24  LEU A C   1 
ATOM 145  O O   . LEU A 1 24  ? 33.897  -54.358 -150.460 1.00 72.02  ? 24  LEU A O   1 
ATOM 146  C CB  . LEU A 1 24  ? 35.358  -51.565 -150.878 1.00 62.02  ? 24  LEU A CB  1 
ATOM 147  C CG  . LEU A 1 24  ? 35.467  -50.071 -150.593 1.00 65.62  ? 24  LEU A CG  1 
ATOM 148  C CD1 . LEU A 1 24  ? 36.862  -49.730 -150.105 1.00 66.96  ? 24  LEU A CD1 1 
ATOM 149  C CD2 . LEU A 1 24  ? 35.120  -49.276 -151.833 1.00 59.45  ? 24  LEU A CD2 1 
ATOM 150  N N   . PRO A 1 25  ? 34.166  -54.046 -152.658 1.00 45.94  ? 25  PRO A N   1 
ATOM 151  C CA  . PRO A 1 25  ? 34.164  -55.487 -152.914 1.00 53.95  ? 25  PRO A CA  1 
ATOM 152  C C   . PRO A 1 25  ? 35.467  -56.137 -152.487 1.00 60.70  ? 25  PRO A C   1 
ATOM 153  O O   . PRO A 1 25  ? 36.535  -55.524 -152.513 1.00 72.71  ? 25  PRO A O   1 
ATOM 154  C CB  . PRO A 1 25  ? 33.970  -55.585 -154.430 1.00 60.41  ? 25  PRO A CB  1 
ATOM 155  C CG  . PRO A 1 25  ? 34.158  -54.210 -154.971 1.00 54.84  ? 25  PRO A CG  1 
ATOM 156  C CD  . PRO A 1 25  ? 34.446  -53.260 -153.867 1.00 51.03  ? 25  PRO A CD  1 
ATOM 157  N N   . LEU A 1 26  ? 35.365  -57.401 -152.084 1.00 68.76  ? 26  LEU A N   1 
ATOM 158  C CA  . LEU A 1 26  ? 36.523  -58.233 -151.789 1.00 69.96  ? 26  LEU A CA  1 
ATOM 159  C C   . LEU A 1 26  ? 36.384  -59.539 -152.550 1.00 72.90  ? 26  LEU A C   1 
ATOM 160  O O   . LEU A 1 26  ? 35.295  -60.116 -152.597 1.00 77.25  ? 26  LEU A O   1 
ATOM 161  C CB  . LEU A 1 26  ? 36.658  -58.509 -150.294 1.00 69.30  ? 26  LEU A CB  1 
ATOM 162  C CG  . LEU A 1 26  ? 37.618  -59.649 -149.961 1.00 65.85  ? 26  LEU A CG  1 
ATOM 163  C CD1 . LEU A 1 26  ? 39.039  -59.222 -150.230 1.00 68.03  ? 26  LEU A CD1 1 
ATOM 164  C CD2 . LEU A 1 26  ? 37.461  -60.082 -148.523 1.00 70.51  ? 26  LEU A CD2 1 
ATOM 165  N N   . PHE A 1 27  ? 37.478  -60.002 -153.143 1.00 70.94  ? 27  PHE A N   1 
ATOM 166  C CA  . PHE A 1 27  ? 37.472  -61.207 -153.956 1.00 68.26  ? 27  PHE A CA  1 
ATOM 167  C C   . PHE A 1 27  ? 38.502  -62.194 -153.431 1.00 78.34  ? 27  PHE A C   1 
ATOM 168  O O   . PHE A 1 27  ? 39.707  -61.973 -153.583 1.00 84.31  ? 27  PHE A O   1 
ATOM 169  C CB  . PHE A 1 27  ? 37.762  -60.871 -155.417 1.00 68.81  ? 27  PHE A CB  1 
ATOM 170  C CG  . PHE A 1 27  ? 37.599  -62.029 -156.348 1.00 68.46  ? 27  PHE A CG  1 
ATOM 171  C CD1 . PHE A 1 27  ? 36.350  -62.547 -156.617 1.00 74.06  ? 27  PHE A CD1 1 
ATOM 172  C CD2 . PHE A 1 27  ? 38.694  -62.592 -156.965 1.00 73.33  ? 27  PHE A CD2 1 
ATOM 173  C CE1 . PHE A 1 27  ? 36.199  -63.608 -157.477 1.00 74.54  ? 27  PHE A CE1 1 
ATOM 174  C CE2 . PHE A 1 27  ? 38.547  -63.652 -157.827 1.00 76.70  ? 27  PHE A CE2 1 
ATOM 175  C CZ  . PHE A 1 27  ? 37.299  -64.160 -158.082 1.00 77.00  ? 27  PHE A CZ  1 
ATOM 176  N N   . LEU A 1 28  ? 38.016  -63.254 -152.783 1.00 83.23  ? 28  LEU A N   1 
ATOM 177  C CA  . LEU A 1 28  ? 38.923  -64.295 -152.252 1.00 76.00  ? 28  LEU A CA  1 
ATOM 178  C C   . LEU A 1 28  ? 39.349  -65.144 -153.439 1.00 77.24  ? 28  LEU A C   1 
ATOM 179  O O   . LEU A 1 28  ? 38.493  -65.854 -153.987 1.00 82.48  ? 28  LEU A O   1 
ATOM 180  C CB  . LEU A 1 28  ? 38.207  -65.148 -151.216 1.00 71.78  ? 28  LEU A CB  1 
ATOM 181  C CG  . LEU A 1 28  ? 38.831  -65.175 -149.821 1.00 73.46  ? 28  LEU A CG  1 
ATOM 182  C CD1 . LEU A 1 28  ? 38.142  -66.230 -148.984 1.00 76.54  ? 28  LEU A CD1 1 
ATOM 183  C CD2 . LEU A 1 28  ? 40.309  -65.471 -149.942 1.00 74.24  ? 28  LEU A CD2 1 
ATOM 184  N N   . ALA A 1 29  ? 40.616  -65.047 -153.820 1.00 86.36  ? 29  ALA A N   1 
ATOM 185  C CA  . ALA A 1 29  ? 41.125  -65.848 -154.949 1.00 88.25  ? 29  ALA A CA  1 
ATOM 186  C C   . ALA A 1 29  ? 41.807  -67.109 -154.431 1.00 85.91  ? 29  ALA A C   1 
ATOM 187  O O   . ALA A 1 29  ? 41.528  -67.552 -153.301 1.00 74.29  ? 29  ALA A O   1 
ATOM 188  C CB  . ALA A 1 29  ? 42.086  -65.023 -155.752 1.00 88.54  ? 29  ALA A CB  1 
ATOM 189  N N   . SER A 1 30  ? 42.681  -67.673 -155.251 1.00 115.72 ? 30  SER A N   1 
ATOM 190  C CA  . SER A 1 30  ? 43.428  -68.878 -154.847 1.00 116.71 ? 30  SER A CA  1 
ATOM 191  C C   . SER A 1 30  ? 44.824  -68.788 -155.455 1.00 116.96 ? 30  SER A C   1 
ATOM 192  O O   . SER A 1 30  ? 45.388  -69.839 -155.812 1.00 112.46 ? 30  SER A O   1 
ATOM 193  C CB  . SER A 1 30  ? 42.693  -70.092 -155.332 1.00 30.00  ? 30  SER A CB  1 
ATOM 194  N N   . THR A 1 31  ? 45.353  -67.569 -155.576 1.00 117.32 ? 31  THR A N   1 
ATOM 195  C CA  . THR A 1 31  ? 46.675  -67.363 -156.204 1.00 116.39 ? 31  THR A CA  1 
ATOM 196  C C   . THR A 1 31  ? 47.592  -66.670 -155.210 1.00 112.70 ? 31  THR A C   1 
ATOM 197  O O   . THR A 1 31  ? 47.148  -65.703 -154.570 1.00 105.29 ? 31  THR A O   1 
ATOM 198  C CB  . THR A 1 31  ? 46.522  -66.530 -157.441 1.00 118.65 ? 31  THR A CB  1 
ATOM 199  N N   . ASP A 1 32  ? 48.837  -67.131 -155.117 1.00 113.34 ? 32  ASP A N   1 
ATOM 200  C CA  . ASP A 1 32  ? 49.766  -66.570 -154.113 1.00 115.29 ? 32  ASP A CA  1 
ATOM 201  C C   . ASP A 1 32  ? 50.669  -65.529 -154.765 1.00 113.97 ? 32  ASP A C   1 
ATOM 202  O O   . ASP A 1 32  ? 51.828  -65.377 -154.346 1.00 116.63 ? 32  ASP A O   1 
ATOM 203  C CB  . ASP A 1 32  ? 50.557  -67.696 -153.506 1.00 114.64 ? 32  ASP A CB  1 
ATOM 204  N N   . ASN A 1 33  ? 50.145  -64.816 -155.755 1.00 108.09 ? 33  ASN A N   1 
ATOM 205  C CA  . ASN A 1 33  ? 50.989  -63.841 -156.487 1.00 107.69 ? 33  ASN A CA  1 
ATOM 206  C C   . ASN A 1 33  ? 51.606  -62.861 -155.489 1.00 107.84 ? 33  ASN A C   1 
ATOM 207  O O   . ASN A 1 33  ? 52.751  -62.449 -155.720 1.00 108.41 ? 33  ASN A O   1 
ATOM 208  C CB  . ASN A 1 33  ? 50.203  -63.168 -157.602 1.00 107.16 ? 33  ASN A CB  1 
ATOM 209  C CG  . ASN A 1 33  ? 49.704  -64.175 -158.608 1.00 107.48 ? 33  ASN A CG  1 
ATOM 210  O OD1 . ASN A 1 33  ? 49.472  -65.337 -158.258 1.00 107.93 ? 33  ASN A OD1 1 
ATOM 211  N ND2 . ASN A 1 33  ? 49.541  -63.762 -159.855 1.00 108.43 ? 33  ASN A ND2 1 
ATOM 212  N N   . PHE A 1 34  ? 50.873  -62.543 -154.421 1.00 105.91 ? 34  PHE A N   1 
ATOM 213  C CA  . PHE A 1 34  ? 51.375  -61.580 -153.403 1.00 105.09 ? 34  PHE A CA  1 
ATOM 214  C C   . PHE A 1 34  ? 51.536  -62.305 -152.076 1.00 101.81 ? 34  PHE A C   1 
ATOM 215  O O   . PHE A 1 34  ? 50.921  -63.368 -151.889 1.00 98.61  ? 34  PHE A O   1 
ATOM 216  C CB  . PHE A 1 34  ? 50.468  -60.348 -153.314 1.00 105.30 ? 34  PHE A CB  1 
ATOM 217  C CG  . PHE A 1 34  ? 48.982  -60.582 -153.088 1.00 106.54 ? 34  PHE A CG  1 
ATOM 218  C CD1 . PHE A 1 34  ? 48.121  -60.780 -154.157 1.00 106.66 ? 34  PHE A CD1 1 
ATOM 219  C CD2 . PHE A 1 34  ? 48.447  -60.562 -151.808 1.00 106.06 ? 34  PHE A CD2 1 
ATOM 220  C CE1 . PHE A 1 34  ? 46.769  -60.984 -153.946 1.00 106.34 ? 34  PHE A CE1 1 
ATOM 221  C CE2 . PHE A 1 34  ? 47.094  -60.764 -151.603 1.00 104.60 ? 34  PHE A CE2 1 
ATOM 222  C CZ  . PHE A 1 34  ? 46.260  -60.973 -152.672 1.00 104.63 ? 34  PHE A CZ  1 
ATOM 223  N N   . GLU A 1 35  ? 52.336  -61.743 -151.172 1.00 108.58 ? 35  GLU A N   1 
ATOM 224  C CA  . GLU A 1 35  ? 52.633  -62.455 -149.908 1.00 108.92 ? 35  GLU A CA  1 
ATOM 225  C C   . GLU A 1 35  ? 51.620  -62.097 -148.830 1.00 110.74 ? 35  GLU A C   1 
ATOM 226  O O   . GLU A 1 35  ? 51.354  -62.933 -147.946 1.00 108.70 ? 35  GLU A O   1 
ATOM 227  C CB  . GLU A 1 35  ? 54.027  -62.124 -149.450 1.00 30.00  ? 35  GLU A CB  1 
ATOM 228  N N   . GLU A 1 36  ? 51.085  -60.882 -148.902 1.00 106.79 ? 36  GLU A N   1 
ATOM 229  C CA  . GLU A 1 36  ? 50.095  -60.442 -147.893 1.00 102.44 ? 36  GLU A CA  1 
ATOM 230  C C   . GLU A 1 36  ? 48.778  -61.198 -148.102 1.00 104.47 ? 36  GLU A C   1 
ATOM 231  O O   . GLU A 1 36  ? 48.688  -62.014 -149.034 1.00 110.99 ? 36  GLU A O   1 
ATOM 232  C CB  . GLU A 1 36  ? 49.881  -58.935 -147.969 1.00 99.20  ? 36  GLU A CB  1 
ATOM 233  C CG  . GLU A 1 36  ? 51.079  -58.188 -148.544 1.00 103.37 ? 36  GLU A CG  1 
ATOM 234  C CD  . GLU A 1 36  ? 50.998  -58.057 -150.051 1.00 108.46 ? 36  GLU A CD  1 
ATOM 235  O OE1 . GLU A 1 36  ? 51.705  -58.820 -150.737 1.00 110.50 ? 36  GLU A OE1 1 
ATOM 236  O OE2 . GLU A 1 36  ? 50.223  -57.207 -150.531 1.00 110.21 ? 36  GLU A OE2 1 
ATOM 237  N N   . ARG A 1 37  ? 47.799  -60.943 -147.255 1.00 90.51  ? 37  ARG A N   1 
ATOM 238  C CA  . ARG A 1 37  ? 46.498  -61.593 -147.324 1.00 91.79  ? 37  ARG A CA  1 
ATOM 239  C C   . ARG A 1 37  ? 45.489  -60.802 -148.141 1.00 96.28  ? 37  ARG A C   1 
ATOM 240  O O   . ARG A 1 37  ? 44.703  -61.392 -148.884 1.00 101.85 ? 37  ARG A O   1 
ATOM 241  C CB  . ARG A 1 37  ? 45.938  -61.816 -145.920 1.00 91.32  ? 37  ARG A CB  1 
ATOM 242  C CG  . ARG A 1 37  ? 46.969  -62.281 -144.920 1.00 94.47  ? 37  ARG A CG  1 
ATOM 243  C CD  . ARG A 1 37  ? 47.346  -63.727 -145.165 1.00 97.65  ? 37  ARG A CD  1 
ATOM 244  N NE  . ARG A 1 37  ? 46.186  -64.558 -145.452 1.00 94.68  ? 37  ARG A NE  1 
ATOM 245  C CZ  . ARG A 1 37  ? 46.253  -65.813 -145.870 1.00 95.27  ? 37  ARG A CZ  1 
ATOM 246  N NH1 . ARG A 1 37  ? 47.413  -66.418 -146.058 1.00 97.74  ? 37  ARG A NH1 1 
ATOM 247  N NH2 . ARG A 1 37  ? 45.126  -66.482 -146.095 1.00 95.27  ? 37  ARG A NH2 1 
ATOM 248  N N   . ILE A 1 38  ? 45.489  -59.481 -148.011 1.00 88.77  ? 38  ILE A N   1 
ATOM 249  C CA  . ILE A 1 38  ? 44.569  -58.611 -148.732 1.00 83.60  ? 38  ILE A CA  1 
ATOM 250  C C   . ILE A 1 38  ? 45.374  -57.483 -149.352 1.00 86.81  ? 38  ILE A C   1 
ATOM 251  O O   . ILE A 1 38  ? 46.136  -56.806 -148.656 1.00 94.80  ? 38  ILE A O   1 
ATOM 252  C CB  . ILE A 1 38  ? 43.480  -58.044 -147.805 1.00 81.55  ? 38  ILE A CB  1 
ATOM 253  C CG1 . ILE A 1 38  ? 42.550  -59.157 -147.334 1.00 82.86  ? 38  ILE A CG1 1 
ATOM 254  C CG2 . ILE A 1 38  ? 42.695  -56.962 -148.514 1.00 82.78  ? 38  ILE A CG2 1 
ATOM 255  C CD1 . ILE A 1 38  ? 41.308  -58.647 -146.657 1.00 86.62  ? 38  ILE A CD1 1 
ATOM 256  N N   . ARG A 1 39  ? 45.207  -57.278 -150.653 1.00 83.10  ? 39  ARG A N   1 
ATOM 257  C CA  . ARG A 1 39  ? 45.863  -56.179 -151.345 1.00 87.28  ? 39  ARG A CA  1 
ATOM 258  C C   . ARG A 1 39  ? 44.831  -55.421 -152.160 1.00 91.86  ? 39  ARG A C   1 
ATOM 259  O O   . ARG A 1 39  ? 44.065  -56.027 -152.914 1.00 94.70  ? 39  ARG A O   1 
ATOM 260  C CB  . ARG A 1 39  ? 46.987  -56.685 -152.247 1.00 85.63  ? 39  ARG A CB  1 
ATOM 261  C CG  . ARG A 1 39  ? 47.753  -55.577 -152.932 1.00 87.74  ? 39  ARG A CG  1 
ATOM 262  C CD  . ARG A 1 39  ? 48.879  -56.136 -153.769 1.00 89.75  ? 39  ARG A CD  1 
ATOM 263  N NE  . ARG A 1 39  ? 50.135  -56.146 -153.033 1.00 91.88  ? 39  ARG A NE  1 
ATOM 264  C CZ  . ARG A 1 39  ? 51.251  -56.712 -153.468 1.00 95.20  ? 39  ARG A CZ  1 
ATOM 265  N NH1 . ARG A 1 39  ? 51.305  -57.317 -154.643 1.00 91.07  ? 39  ARG A NH1 1 
ATOM 266  N NH2 . ARG A 1 39  ? 52.339  -56.668 -152.707 1.00 98.75  ? 39  ARG A NH2 1 
ATOM 267  N N   . GLY A 1 40  ? 44.815  -54.100 -152.012 1.00 90.73  ? 40  GLY A N   1 
ATOM 268  C CA  . GLY A 1 40  ? 43.841  -53.274 -152.697 1.00 87.29  ? 40  GLY A CA  1 
ATOM 269  C C   . GLY A 1 40  ? 44.344  -52.813 -154.054 1.00 86.22  ? 40  GLY A C   1 
ATOM 270  O O   . GLY A 1 40  ? 45.530  -52.546 -154.236 1.00 89.14  ? 40  GLY A O   1 
ATOM 271  N N   . TYR A 1 41  ? 43.422  -52.723 -155.004 1.00 84.49  ? 41  TYR A N   1 
ATOM 272  C CA  . TYR A 1 41  ? 43.710  -52.227 -156.338 1.00 82.83  ? 41  TYR A CA  1 
ATOM 273  C C   . TYR A 1 41  ? 42.697  -51.156 -156.707 1.00 85.85  ? 41  TYR A C   1 
ATOM 274  O O   . TYR A 1 41  ? 41.529  -51.227 -156.322 1.00 93.68  ? 41  TYR A O   1 
ATOM 275  C CB  . TYR A 1 41  ? 43.681  -53.347 -157.364 1.00 83.45  ? 41  TYR A CB  1 
ATOM 276  C CG  . TYR A 1 41  ? 44.743  -54.393 -157.149 1.00 88.27  ? 41  TYR A CG  1 
ATOM 277  C CD1 . TYR A 1 41  ? 46.057  -54.159 -157.522 1.00 88.17  ? 41  TYR A CD1 1 
ATOM 278  C CD2 . TYR A 1 41  ? 44.433  -55.613 -156.571 1.00 87.09  ? 41  TYR A CD2 1 
ATOM 279  C CE1 . TYR A 1 41  ? 47.030  -55.112 -157.328 1.00 89.35  ? 41  TYR A CE1 1 
ATOM 280  C CE2 . TYR A 1 41  ? 45.401  -56.573 -156.374 1.00 89.06  ? 41  TYR A CE2 1 
ATOM 281  C CZ  . TYR A 1 41  ? 46.697  -56.316 -156.754 1.00 90.53  ? 41  TYR A CZ  1 
ATOM 282  O OH  . TYR A 1 41  ? 47.665  -57.270 -156.558 1.00 94.54  ? 41  TYR A OH  1 
ATOM 283  N N   . THR A 1 42  ? 43.154  -50.159 -157.459 1.00 74.84  ? 42  THR A N   1 
ATOM 284  C CA  . THR A 1 42  ? 42.315  -49.028 -157.814 1.00 78.67  ? 42  THR A CA  1 
ATOM 285  C C   . THR A 1 42  ? 41.916  -48.996 -159.281 1.00 79.23  ? 42  THR A C   1 
ATOM 286  O O   . THR A 1 42  ? 41.138  -48.121 -159.670 1.00 78.01  ? 42  THR A O   1 
ATOM 287  C CB  . THR A 1 42  ? 43.020  -47.716 -157.458 1.00 82.72  ? 42  THR A CB  1 
ATOM 288  O OG1 . THR A 1 42  ? 44.218  -47.594 -158.230 1.00 88.84  ? 42  THR A OG1 1 
ATOM 289  C CG2 . THR A 1 42  ? 43.376  -47.697 -155.985 1.00 77.68  ? 42  THR A CG2 1 
ATOM 290  N N   . SER A 1 43  ? 42.428  -49.908 -160.101 1.00 88.92  ? 43  SER A N   1 
ATOM 291  C CA  . SER A 1 43  ? 42.047  -49.973 -161.505 1.00 89.49  ? 43  SER A CA  1 
ATOM 292  C C   . SER A 1 43  ? 42.383  -51.360 -162.028 1.00 89.70  ? 43  SER A C   1 
ATOM 293  O O   . SER A 1 43  ? 43.039  -52.156 -161.355 1.00 95.55  ? 43  SER A O   1 
ATOM 294  C CB  . SER A 1 43  ? 42.753  -48.902 -162.338 1.00 87.24  ? 43  SER A CB  1 
ATOM 295  O OG  . SER A 1 43  ? 43.874  -49.448 -163.009 1.00 82.72  ? 43  SER A OG  1 
ATOM 296  N N   . LEU A 1 44  ? 41.917  -51.640 -163.244 1.00 84.82  ? 44  LEU A N   1 
ATOM 297  C CA  . LEU A 1 44  ? 42.234  -52.917 -163.871 1.00 87.07  ? 44  LEU A CA  1 
ATOM 298  C C   . LEU A 1 44  ? 43.715  -53.027 -164.202 1.00 93.86  ? 44  LEU A C   1 
ATOM 299  O O   . LEU A 1 44  ? 44.289  -54.119 -164.118 1.00 96.64  ? 44  LEU A O   1 
ATOM 300  C CB  . LEU A 1 44  ? 41.397  -53.105 -165.134 1.00 85.39  ? 44  LEU A CB  1 
ATOM 301  C CG  . LEU A 1 44  ? 41.552  -54.466 -165.803 1.00 84.50  ? 44  LEU A CG  1 
ATOM 302  C CD1 . LEU A 1 44  ? 41.089  -55.561 -164.870 1.00 84.94  ? 44  LEU A CD1 1 
ATOM 303  C CD2 . LEU A 1 44  ? 40.774  -54.504 -167.102 1.00 89.01  ? 44  LEU A CD2 1 
ATOM 304  N N   . THR A 1 45  ? 44.347  -51.917 -164.586 1.00 92.58  ? 45  THR A N   1 
ATOM 305  C CA  . THR A 1 45  ? 45.760  -51.962 -164.944 1.00 87.83  ? 45  THR A CA  1 
ATOM 306  C C   . THR A 1 45  ? 46.617  -52.374 -163.757 1.00 85.58  ? 45  THR A C   1 
ATOM 307  O O   . THR A 1 45  ? 47.555  -53.165 -163.904 1.00 84.94  ? 45  THR A O   1 
ATOM 308  C CB  . THR A 1 45  ? 46.210  -50.608 -165.482 1.00 89.22  ? 45  THR A CB  1 
ATOM 309  O OG1 . THR A 1 45  ? 45.242  -50.122 -166.417 1.00 91.98  ? 45  THR A OG1 1 
ATOM 310  C CG2 . THR A 1 45  ? 47.550  -50.742 -166.177 1.00 89.66  ? 45  THR A CG2 1 
ATOM 311  N N   . GLU A 1 46  ? 46.310  -51.850 -162.571 1.00 89.48  ? 46  GLU A N   1 
ATOM 312  C CA  . GLU A 1 46  ? 47.046  -52.260 -161.382 1.00 92.07  ? 46  GLU A CA  1 
ATOM 313  C C   . GLU A 1 46  ? 46.853  -53.739 -161.096 1.00 95.78  ? 46  GLU A C   1 
ATOM 314  O O   . GLU A 1 46  ? 47.786  -54.411 -160.648 1.00 106.22 ? 46  GLU A O   1 
ATOM 315  C CB  . GLU A 1 46  ? 46.618  -51.426 -160.180 1.00 92.43  ? 46  GLU A CB  1 
ATOM 316  C CG  . GLU A 1 46  ? 47.007  -49.970 -160.286 1.00 98.95  ? 46  GLU A CG  1 
ATOM 317  C CD  . GLU A 1 46  ? 46.666  -49.192 -159.039 1.00 102.53 ? 46  GLU A CD  1 
ATOM 318  O OE1 . GLU A 1 46  ? 46.179  -49.808 -158.070 1.00 102.33 ? 46  GLU A OE1 1 
ATOM 319  O OE2 . GLU A 1 46  ? 46.876  -47.962 -159.029 1.00 104.24 ? 46  GLU A OE2 1 
ATOM 320  N N   . VAL A 1 47  ? 45.651  -54.262 -161.342 1.00 87.05  ? 47  VAL A N   1 
ATOM 321  C CA  . VAL A 1 47  ? 45.424  -55.692 -161.186 1.00 86.67  ? 47  VAL A CA  1 
ATOM 322  C C   . VAL A 1 47  ? 46.288  -56.474 -162.162 1.00 93.05  ? 47  VAL A C   1 
ATOM 323  O O   . VAL A 1 47  ? 46.864  -57.511 -161.813 1.00 94.96  ? 47  VAL A O   1 
ATOM 324  C CB  . VAL A 1 47  ? 43.933  -56.017 -161.371 1.00 91.90  ? 47  VAL A CB  1 
ATOM 325  C CG1 . VAL A 1 47  ? 43.701  -57.511 -161.267 1.00 93.44  ? 47  VAL A CG1 1 
ATOM 326  C CG2 . VAL A 1 47  ? 43.102  -55.276 -160.349 1.00 93.98  ? 47  VAL A CG2 1 
ATOM 327  N N   . ALA A 1 48  ? 46.397  -55.989 -163.398 1.00 99.60  ? 48  ALA A N   1 
ATOM 328  C CA  . ALA A 1 48  ? 47.161  -56.694 -164.419 1.00 100.11 ? 48  ALA A CA  1 
ATOM 329  C C   . ALA A 1 48  ? 48.644  -56.781 -164.089 1.00 100.50 ? 48  ALA A C   1 
ATOM 330  O O   . ALA A 1 48  ? 49.337  -57.643 -164.636 1.00 99.09  ? 48  ALA A O   1 
ATOM 331  C CB  . ALA A 1 48  ? 46.975  -56.016 -165.775 1.00 99.27  ? 48  ALA A CB  1 
ATOM 332  N N   . GLU A 1 49  ? 49.150  -55.910 -163.213 1.00 102.47 ? 49  GLU A N   1 
ATOM 333  C CA  . GLU A 1 49  ? 50.567  -55.953 -162.878 1.00 98.89  ? 49  GLU A CA  1 
ATOM 334  C C   . GLU A 1 49  ? 50.922  -57.186 -162.062 1.00 101.39 ? 49  GLU A C   1 
ATOM 335  O O   . GLU A 1 49  ? 52.061  -57.660 -162.125 1.00 104.66 ? 49  GLU A O   1 
ATOM 336  C CB  . GLU A 1 49  ? 50.972  -54.691 -162.120 1.00 100.65 ? 49  GLU A CB  1 
ATOM 337  C CG  . GLU A 1 49  ? 51.097  -53.462 -162.992 1.00 103.17 ? 49  GLU A CG  1 
ATOM 338  C CD  . GLU A 1 49  ? 51.026  -52.184 -162.191 1.00 107.28 ? 49  GLU A CD  1 
ATOM 339  O OE1 . GLU A 1 49  ? 50.493  -52.219 -161.063 1.00 104.80 ? 49  GLU A OE1 1 
ATOM 340  O OE2 . GLU A 1 49  ? 51.509  -51.145 -162.685 1.00 112.72 ? 49  GLU A OE2 1 
ATOM 341  N N   . ASP A 1 50  ? 49.976  -57.715 -161.289 1.00 98.58  ? 50  ASP A N   1 
ATOM 342  C CA  . ASP A 1 50  ? 50.229  -58.882 -160.460 1.00 99.57  ? 50  ASP A CA  1 
ATOM 343  C C   . ASP A 1 50  ? 49.461  -60.117 -160.905 1.00 99.20  ? 50  ASP A C   1 
ATOM 344  O O   . ASP A 1 50  ? 49.655  -61.187 -160.321 1.00 100.55 ? 50  ASP A O   1 
ATOM 345  C CB  . ASP A 1 50  ? 49.882  -58.576 -158.997 1.00 100.90 ? 50  ASP A CB  1 
ATOM 346  C CG  . ASP A 1 50  ? 50.596  -57.350 -158.480 1.00 102.75 ? 50  ASP A CG  1 
ATOM 347  O OD1 . ASP A 1 50  ? 51.593  -56.936 -159.104 1.00 103.49 ? 50  ASP A OD1 1 
ATOM 348  O OD2 . ASP A 1 50  ? 50.165  -56.801 -157.445 1.00 103.06 ? 50  ASP A OD2 1 
ATOM 349  N N   . PHE A 1 51  ? 48.601  -60.001 -161.911 1.00 93.86  ? 51  PHE A N   1 
ATOM 350  C CA  . PHE A 1 51  ? 47.801  -61.118 -162.381 1.00 92.81  ? 51  PHE A CA  1 
ATOM 351  C C   . PHE A 1 51  ? 47.794  -61.126 -163.900 1.00 94.64  ? 51  PHE A C   1 
ATOM 352  O O   . PHE A 1 51  ? 47.876  -60.077 -164.542 1.00 94.03  ? 51  PHE A O   1 
ATOM 353  C CB  . PHE A 1 51  ? 46.368  -61.034 -161.856 1.00 92.26  ? 51  PHE A CB  1 
ATOM 354  C CG  . PHE A 1 51  ? 46.253  -61.253 -160.381 1.00 89.78  ? 51  PHE A CG  1 
ATOM 355  C CD1 . PHE A 1 51  ? 46.366  -62.519 -159.846 1.00 90.61  ? 51  PHE A CD1 1 
ATOM 356  C CD2 . PHE A 1 51  ? 46.051  -60.189 -159.526 1.00 92.72  ? 51  PHE A CD2 1 
ATOM 357  C CE1 . PHE A 1 51  ? 46.261  -62.721 -158.490 1.00 95.25  ? 51  PHE A CE1 1 
ATOM 358  C CE2 . PHE A 1 51  ? 45.948  -60.386 -158.170 1.00 94.62  ? 51  PHE A CE2 1 
ATOM 359  C CZ  . PHE A 1 51  ? 46.053  -61.651 -157.651 1.00 97.20  ? 51  PHE A CZ  1 
ATOM 360  N N   . ASP A 1 52  ? 47.694  -62.319 -164.470 1.00 107.24 ? 52  ASP A N   1 
ATOM 361  C CA  . ASP A 1 52  ? 47.635  -62.483 -165.912 1.00 108.94 ? 52  ASP A CA  1 
ATOM 362  C C   . ASP A 1 52  ? 46.187  -62.626 -166.364 1.00 110.34 ? 52  ASP A C   1 
ATOM 363  O O   . ASP A 1 52  ? 45.277  -62.856 -165.566 1.00 112.65 ? 52  ASP A O   1 
ATOM 364  C CB  . ASP A 1 52  ? 48.456  -63.696 -166.349 1.00 109.22 ? 52  ASP A CB  1 
ATOM 365  C CG  . ASP A 1 52  ? 48.059  -64.957 -165.618 1.00 114.10 ? 52  ASP A CG  1 
ATOM 366  O OD1 . ASP A 1 52  ? 46.959  -65.479 -165.890 1.00 116.54 ? 52  ASP A OD1 1 
ATOM 367  O OD2 . ASP A 1 52  ? 48.847  -65.424 -164.769 1.00 115.47 ? 52  ASP A OD2 1 
ATOM 368  N N   . GLU A 1 53  ? 45.987  -62.500 -167.676 1.00 105.91 ? 53  GLU A N   1 
ATOM 369  C CA  . GLU A 1 53  ? 44.640  -62.516 -168.231 1.00 101.22 ? 53  GLU A CA  1 
ATOM 370  C C   . GLU A 1 53  ? 43.931  -63.838 -167.994 1.00 103.76 ? 53  GLU A C   1 
ATOM 371  O O   . GLU A 1 53  ? 42.697  -63.881 -168.029 1.00 107.36 ? 53  GLU A O   1 
ATOM 372  C CB  . GLU A 1 53  ? 44.688  -62.219 -169.729 1.00 104.43 ? 53  GLU A CB  1 
ATOM 373  C CG  . GLU A 1 53  ? 44.950  -60.762 -170.081 1.00 109.98 ? 53  GLU A CG  1 
ATOM 374  C CD  . GLU A 1 53  ? 46.351  -60.304 -169.714 1.00 112.51 ? 53  GLU A CD  1 
ATOM 375  O OE1 . GLU A 1 53  ? 47.245  -61.164 -169.568 1.00 112.93 ? 53  GLU A OE1 1 
ATOM 376  O OE2 . GLU A 1 53  ? 46.560  -59.081 -169.577 1.00 110.92 ? 53  GLU A OE2 1 
ATOM 377  N N   . SER A 1 54  ? 44.672  -64.916 -167.758 1.00 104.14 ? 54  SER A N   1 
ATOM 378  C CA  . SER A 1 54  ? 44.068  -66.222 -167.547 1.00 105.69 ? 54  SER A CA  1 
ATOM 379  C C   . SER A 1 54  ? 43.695  -66.485 -166.096 1.00 105.11 ? 54  SER A C   1 
ATOM 380  O O   . SER A 1 54  ? 43.025  -67.484 -165.818 1.00 105.35 ? 54  SER A O   1 
ATOM 381  C CB  . SER A 1 54  ? 45.013  -67.323 -168.031 1.00 106.06 ? 54  SER A CB  1 
ATOM 382  O OG  . SER A 1 54  ? 45.979  -67.627 -167.042 1.00 109.29 ? 54  SER A OG  1 
ATOM 383  N N   . THR A 1 55  ? 44.107  -65.629 -165.171 1.00 101.32 ? 55  THR A N   1 
ATOM 384  C CA  . THR A 1 55  ? 43.789  -65.838 -163.769 1.00 97.68  ? 55  THR A CA  1 
ATOM 385  C C   . THR A 1 55  ? 42.352  -65.430 -163.481 1.00 98.88  ? 55  THR A C   1 
ATOM 386  O O   . THR A 1 55  ? 41.793  -64.542 -164.128 1.00 101.34 ? 55  THR A O   1 
ATOM 387  C CB  . THR A 1 55  ? 44.739  -65.044 -162.874 1.00 103.46 ? 55  THR A CB  1 
ATOM 388  O OG1 . THR A 1 55  ? 44.971  -63.753 -163.449 1.00 106.97 ? 55  THR A OG1 1 
ATOM 389  C CG2 . THR A 1 55  ? 46.061  -65.777 -162.721 1.00 104.16 ? 55  THR A CG2 1 
ATOM 390  N N   . ALA A 1 56  ? 41.753  -66.098 -162.495 1.00 87.32  ? 56  ALA A N   1 
ATOM 391  C CA  . ALA A 1 56  ? 40.382  -65.780 -162.121 1.00 85.18  ? 56  ALA A CA  1 
ATOM 392  C C   . ALA A 1 56  ? 40.273  -64.388 -161.518 1.00 87.08  ? 56  ALA A C   1 
ATOM 393  O O   . ALA A 1 56  ? 39.258  -63.710 -161.708 1.00 89.75  ? 56  ALA A O   1 
ATOM 394  C CB  . ALA A 1 56  ? 39.851  -66.822 -161.142 1.00 82.22  ? 56  ALA A CB  1 
ATOM 395  N N   . ALA A 1 57  ? 41.298  -63.948 -160.788 1.00 80.92  ? 57  ALA A N   1 
ATOM 396  C CA  . ALA A 1 57  ? 41.256  -62.620 -160.190 1.00 79.38  ? 57  ALA A CA  1 
ATOM 397  C C   . ALA A 1 57  ? 41.176  -61.538 -161.257 1.00 86.78  ? 57  ALA A C   1 
ATOM 398  O O   . ALA A 1 57  ? 40.428  -60.566 -161.110 1.00 91.50  ? 57  ALA A O   1 
ATOM 399  C CB  . ALA A 1 57  ? 42.479  -62.406 -159.300 1.00 81.61  ? 57  ALA A CB  1 
ATOM 400  N N   . TYR A 1 58  ? 41.938  -61.689 -162.341 1.00 83.46  ? 58  TYR A N   1 
ATOM 401  C CA  . TYR A 1 58  ? 41.866  -60.714 -163.422 1.00 81.86  ? 58  TYR A CA  1 
ATOM 402  C C   . TYR A 1 58  ? 40.497  -60.725 -164.082 1.00 86.29  ? 58  TYR A C   1 
ATOM 403  O O   . TYR A 1 58  ? 39.973  -59.670 -164.450 1.00 89.38  ? 58  TYR A O   1 
ATOM 404  C CB  . TYR A 1 58  ? 42.951  -60.981 -164.458 1.00 82.62  ? 58  TYR A CB  1 
ATOM 405  C CG  . TYR A 1 58  ? 42.974  -59.958 -165.564 1.00 84.74  ? 58  TYR A CG  1 
ATOM 406  C CD1 . TYR A 1 58  ? 43.523  -58.703 -165.363 1.00 84.10  ? 58  TYR A CD1 1 
ATOM 407  C CD2 . TYR A 1 58  ? 42.436  -60.243 -166.807 1.00 88.69  ? 58  TYR A CD2 1 
ATOM 408  C CE1 . TYR A 1 58  ? 43.543  -57.764 -166.370 1.00 82.48  ? 58  TYR A CE1 1 
ATOM 409  C CE2 . TYR A 1 58  ? 42.453  -59.312 -167.819 1.00 90.59  ? 58  TYR A CE2 1 
ATOM 410  C CZ  . TYR A 1 58  ? 43.006  -58.074 -167.596 1.00 84.40  ? 58  TYR A CZ  1 
ATOM 411  O OH  . TYR A 1 58  ? 43.020  -57.145 -168.606 1.00 82.00  ? 58  TYR A OH  1 
ATOM 412  N N   . LYS A 1 59  ? 39.906  -61.908 -164.254 1.00 85.15  ? 59  LYS A N   1 
ATOM 413  C CA  . LYS A 1 59  ? 38.567  -61.982 -164.827 1.00 81.83  ? 59  LYS A CA  1 
ATOM 414  C C   . LYS A 1 59  ? 37.559  -61.253 -163.951 1.00 82.00  ? 59  LYS A C   1 
ATOM 415  O O   . LYS A 1 59  ? 36.730  -60.479 -164.446 1.00 91.39  ? 59  LYS A O   1 
ATOM 416  C CB  . LYS A 1 59  ? 38.154  -63.441 -165.006 1.00 84.46  ? 59  LYS A CB  1 
ATOM 417  C CG  . LYS A 1 59  ? 38.900  -64.183 -166.093 1.00 88.20  ? 59  LYS A CG  1 
ATOM 418  C CD  . LYS A 1 59  ? 38.282  -65.548 -166.311 1.00 83.81  ? 59  LYS A CD  1 
ATOM 419  C CE  . LYS A 1 59  ? 39.213  -66.469 -167.059 1.00 85.74  ? 59  LYS A CE  1 
ATOM 420  N NZ  . LYS A 1 59  ? 38.677  -67.852 -167.090 1.00 87.50  ? 59  LYS A NZ  1 
ATOM 421  N N   . ALA A 1 60  ? 37.621  -61.487 -162.640 1.00 74.98  ? 60  ALA A N   1 
ATOM 422  C CA  . ALA A 1 60  ? 36.699  -60.819 -161.731 1.00 81.23  ? 60  ALA A CA  1 
ATOM 423  C C   . ALA A 1 60  ? 36.901  -59.312 -161.757 1.00 77.88  ? 60  ALA A C   1 
ATOM 424  O O   . ALA A 1 60  ? 35.929  -58.548 -161.775 1.00 80.40  ? 60  ALA A O   1 
ATOM 425  C CB  . ALA A 1 60  ? 36.876  -61.359 -160.315 1.00 79.98  ? 60  ALA A CB  1 
ATOM 426  N N   . ALA A 1 61  ? 38.156  -58.864 -161.764 1.00 75.27  ? 61  ALA A N   1 
ATOM 427  C CA  . ALA A 1 61  ? 38.422  -57.432 -161.816 1.00 79.62  ? 61  ALA A CA  1 
ATOM 428  C C   . ALA A 1 61  ? 37.899  -56.822 -163.108 1.00 79.36  ? 61  ALA A C   1 
ATOM 429  O O   . ALA A 1 61  ? 37.321  -55.730 -163.097 1.00 82.73  ? 61  ALA A O   1 
ATOM 430  C CB  . ALA A 1 61  ? 39.917  -57.169 -161.664 1.00 83.53  ? 61  ALA A CB  1 
ATOM 431  N N   . LYS A 1 62  ? 38.091  -57.513 -164.232 1.00 77.10  ? 62  LYS A N   1 
ATOM 432  C CA  . LYS A 1 62  ? 37.589  -57.006 -165.502 1.00 76.66  ? 62  LYS A CA  1 
ATOM 433  C C   . LYS A 1 62  ? 36.074  -56.898 -165.487 1.00 81.37  ? 62  LYS A C   1 
ATOM 434  O O   . LYS A 1 62  ? 35.508  -55.911 -165.971 1.00 81.68  ? 62  LYS A O   1 
ATOM 435  C CB  . LYS A 1 62  ? 38.049  -57.905 -166.645 1.00 75.27  ? 62  LYS A CB  1 
ATOM 436  C CG  . LYS A 1 62  ? 37.159  -57.848 -167.868 1.00 77.14  ? 62  LYS A CG  1 
ATOM 437  C CD  . LYS A 1 62  ? 37.754  -58.635 -169.017 1.00 80.05  ? 62  LYS A CD  1 
ATOM 438  C CE  . LYS A 1 62  ? 38.878  -57.868 -169.685 1.00 82.89  ? 62  LYS A CE  1 
ATOM 439  N NZ  . LYS A 1 62  ? 38.355  -56.797 -170.576 1.00 82.25  ? 62  LYS A NZ  1 
ATOM 440  N N   . GLN A 1 63  ? 35.397  -57.900 -164.925 1.00 82.25  ? 63  GLN A N   1 
ATOM 441  C CA  . GLN A 1 63  ? 33.945  -57.826 -164.825 1.00 76.55  ? 63  GLN A CA  1 
ATOM 442  C C   . GLN A 1 63  ? 33.503  -56.687 -163.920 1.00 80.27  ? 63  GLN A C   1 
ATOM 443  O O   . GLN A 1 63  ? 32.489  -56.039 -164.195 1.00 84.64  ? 63  GLN A O   1 
ATOM 444  C CB  . GLN A 1 63  ? 33.375  -59.147 -164.319 1.00 77.47  ? 63  GLN A CB  1 
ATOM 445  C CG  . GLN A 1 63  ? 33.450  -60.270 -165.328 1.00 84.49  ? 63  GLN A CG  1 
ATOM 446  C CD  . GLN A 1 63  ? 32.290  -60.248 -166.295 1.00 84.43  ? 63  GLN A CD  1 
ATOM 447  O OE1 . GLN A 1 63  ? 31.437  -59.365 -166.232 1.00 88.48  ? 63  GLN A OE1 1 
ATOM 448  N NE2 . GLN A 1 63  ? 32.249  -61.221 -167.194 1.00 80.05  ? 63  GLN A NE2 1 
ATOM 449  N N   . LEU A 1 64  ? 34.246  -56.426 -162.846 1.00 79.05  ? 64  LEU A N   1 
ATOM 450  C CA  . LEU A 1 64  ? 33.862  -55.369 -161.919 1.00 75.58  ? 64  LEU A CA  1 
ATOM 451  C C   . LEU A 1 64  ? 33.897  -54.004 -162.593 1.00 74.89  ? 64  LEU A C   1 
ATOM 452  O O   . LEU A 1 64  ? 32.995  -53.183 -162.402 1.00 82.07  ? 64  LEU A O   1 
ATOM 453  C CB  . LEU A 1 64  ? 34.783  -55.382 -160.701 1.00 74.32  ? 64  LEU A CB  1 
ATOM 454  C CG  . LEU A 1 64  ? 34.198  -54.996 -159.345 1.00 64.36  ? 64  LEU A CG  1 
ATOM 455  C CD1 . LEU A 1 64  ? 35.208  -55.281 -158.266 1.00 71.11  ? 64  LEU A CD1 1 
ATOM 456  C CD2 . LEU A 1 64  ? 33.803  -53.542 -159.303 1.00 73.13  ? 64  LEU A CD2 1 
ATOM 457  N N   . TRP A 1 65  ? 34.931  -53.741 -163.387 1.00 74.75  ? 65  TRP A N   1 
ATOM 458  C CA  . TRP A 1 65  ? 35.178  -52.404 -163.906 1.00 75.83  ? 65  TRP A CA  1 
ATOM 459  C C   . TRP A 1 65  ? 34.604  -52.192 -165.297 1.00 81.29  ? 65  TRP A C   1 
ATOM 460  O O   . TRP A 1 65  ? 35.164  -51.416 -166.081 1.00 89.04  ? 65  TRP A O   1 
ATOM 461  C CB  . TRP A 1 65  ? 36.674  -52.104 -163.894 1.00 77.91  ? 65  TRP A CB  1 
ATOM 462  C CG  . TRP A 1 65  ? 37.133  -51.568 -162.588 1.00 79.88  ? 65  TRP A CG  1 
ATOM 463  C CD1 . TRP A 1 65  ? 36.788  -50.381 -162.034 1.00 81.24  ? 65  TRP A CD1 1 
ATOM 464  C CD2 . TRP A 1 65  ? 38.025  -52.197 -161.667 1.00 81.45  ? 65  TRP A CD2 1 
ATOM 465  N NE1 . TRP A 1 65  ? 37.402  -50.227 -160.818 1.00 81.91  ? 65  TRP A NE1 1 
ATOM 466  C CE2 . TRP A 1 65  ? 38.170  -51.331 -160.572 1.00 81.19  ? 65  TRP A CE2 1 
ATOM 467  C CE3 . TRP A 1 65  ? 38.716  -53.409 -161.663 1.00 80.76  ? 65  TRP A CE3 1 
ATOM 468  C CZ2 . TRP A 1 65  ? 38.977  -51.635 -159.486 1.00 78.91  ? 65  TRP A CZ2 1 
ATOM 469  C CZ3 . TRP A 1 65  ? 39.514  -53.710 -160.586 1.00 82.58  ? 65  TRP A CZ3 1 
ATOM 470  C CH2 . TRP A 1 65  ? 39.640  -52.827 -159.512 1.00 80.34  ? 65  TRP A CH2 1 
ATOM 471  N N   . SER A 1 66  ? 33.501  -52.856 -165.629 1.00 82.32  ? 66  SER A N   1 
ATOM 472  C CA  . SER A 1 66  ? 32.817  -52.642 -166.895 1.00 83.24  ? 66  SER A CA  1 
ATOM 473  C C   . SER A 1 66  ? 31.472  -51.953 -166.711 1.00 85.61  ? 66  SER A C   1 
ATOM 474  O O   . SER A 1 66  ? 30.510  -52.277 -167.412 1.00 90.41  ? 66  SER A O   1 
ATOM 475  C CB  . SER A 1 66  ? 32.633  -53.967 -167.631 1.00 82.23  ? 66  SER A CB  1 
ATOM 476  O OG  . SER A 1 66  ? 31.562  -54.704 -167.073 1.00 89.53  ? 66  SER A OG  1 
ATOM 477  N N   . GLN A 1 67  ? 31.385  -51.005 -165.783 1.00 77.42  ? 67  GLN A N   1 
ATOM 478  C CA  . GLN A 1 67  ? 30.142  -50.318 -165.476 1.00 79.47  ? 67  GLN A CA  1 
ATOM 479  C C   . GLN A 1 67  ? 30.322  -48.816 -165.649 1.00 80.75  ? 67  GLN A C   1 
ATOM 480  O O   . GLN A 1 67  ? 31.438  -48.311 -165.782 1.00 85.66  ? 67  GLN A O   1 
ATOM 481  C CB  . GLN A 1 67  ? 29.679  -50.644 -164.056 1.00 76.65  ? 67  GLN A CB  1 
ATOM 482  C CG  . GLN A 1 67  ? 29.322  -52.106 -163.842 1.00 73.84  ? 67  GLN A CG  1 
ATOM 483  C CD  . GLN A 1 67  ? 28.591  -52.719 -165.011 1.00 75.99  ? 67  GLN A CD  1 
ATOM 484  O OE1 . GLN A 1 67  ? 29.039  -53.706 -165.586 1.00 74.09  ? 67  GLN A OE1 1 
ATOM 485  N NE2 . GLN A 1 67  ? 27.450  -52.144 -165.362 1.00 80.01  ? 67  GLN A NE2 1 
ATOM 486  N N   . THR A 1 68  ? 29.193  -48.096 -165.666 1.00 87.04  ? 68  THR A N   1 
ATOM 487  C CA  . THR A 1 68  ? 29.255  -46.657 -165.925 1.00 88.63  ? 68  THR A CA  1 
ATOM 488  C C   . THR A 1 68  ? 30.003  -45.905 -164.833 1.00 87.49  ? 68  THR A C   1 
ATOM 489  O O   . THR A 1 68  ? 30.897  -45.109 -165.166 1.00 88.24  ? 68  THR A O   1 
ATOM 490  C CB  . THR A 1 68  ? 27.843  -46.105 -166.152 1.00 90.74  ? 68  THR A CB  1 
ATOM 491  N N   . PRO A 1 69  ? 29.715  -46.090 -163.534 1.00 74.85  ? 69  PRO A N   1 
ATOM 492  C CA  . PRO A 1 69  ? 30.648  -45.589 -162.520 1.00 74.47  ? 69  PRO A CA  1 
ATOM 493  C C   . PRO A 1 69  ? 31.842  -46.519 -162.419 1.00 81.10  ? 69  PRO A C   1 
ATOM 494  O O   . PRO A 1 69  ? 31.944  -47.467 -163.202 1.00 84.79  ? 69  PRO A O   1 
ATOM 495  C CB  . PRO A 1 69  ? 29.811  -45.576 -161.236 1.00 69.12  ? 69  PRO A CB  1 
ATOM 496  C CG  . PRO A 1 69  ? 28.404  -45.668 -161.697 1.00 67.83  ? 69  PRO A CG  1 
ATOM 497  C CD  . PRO A 1 69  ? 28.466  -46.536 -162.901 1.00 72.40  ? 69  PRO A CD  1 
ATOM 498  N N   . LYS A 1 70  ? 32.746  -46.287 -161.476 1.00 77.90  ? 70  LYS A N   1 
ATOM 499  C CA  . LYS A 1 70  ? 33.996  -47.032 -161.517 1.00 73.40  ? 70  LYS A CA  1 
ATOM 500  C C   . LYS A 1 70  ? 34.196  -47.958 -160.326 1.00 78.10  ? 70  LYS A C   1 
ATOM 501  O O   . LYS A 1 70  ? 34.931  -48.940 -160.443 1.00 87.05  ? 70  LYS A O   1 
ATOM 502  C CB  . LYS A 1 70  ? 35.176  -46.068 -161.622 1.00 79.16  ? 70  LYS A CB  1 
ATOM 503  N N   . VAL A 1 71  ? 33.561  -47.665 -159.191 1.00 68.97  ? 71  VAL A N   1 
ATOM 504  C CA  . VAL A 1 71  ? 33.830  -48.363 -157.934 1.00 73.81  ? 71  VAL A CA  1 
ATOM 505  C C   . VAL A 1 71  ? 35.262  -48.047 -157.522 1.00 77.73  ? 71  VAL A C   1 
ATOM 506  O O   . VAL A 1 71  ? 36.217  -48.528 -158.140 1.00 80.22  ? 71  VAL A O   1 
ATOM 507  C CB  . VAL A 1 71  ? 33.597  -49.883 -158.040 1.00 63.58  ? 71  VAL A CB  1 
ATOM 508  C CG1 . VAL A 1 71  ? 33.728  -50.534 -156.681 1.00 64.86  ? 71  VAL A CG1 1 
ATOM 509  C CG2 . VAL A 1 71  ? 32.242  -50.171 -158.641 1.00 63.71  ? 71  VAL A CG2 1 
ATOM 510  N N   . THR A 1 72  ? 35.412  -47.235 -156.475 1.00 78.17  ? 72  THR A N   1 
ATOM 511  C CA  . THR A 1 72  ? 36.700  -46.619 -156.162 1.00 79.32  ? 72  THR A CA  1 
ATOM 512  C C   . THR A 1 72  ? 37.822  -47.644 -156.044 1.00 80.84  ? 72  THR A C   1 
ATOM 513  O O   . THR A 1 72  ? 38.869  -47.507 -156.685 1.00 89.88  ? 72  THR A O   1 
ATOM 514  C CB  . THR A 1 72  ? 36.585  -45.813 -154.869 1.00 85.24  ? 72  THR A CB  1 
ATOM 515  O OG1 . THR A 1 72  ? 35.967  -46.616 -153.859 1.00 91.26  ? 72  THR A OG1 1 
ATOM 516  C CG2 . THR A 1 72  ? 35.746  -44.576 -155.091 1.00 81.02  ? 72  THR A CG2 1 
ATOM 517  N N   . GLN A 1 73  ? 37.625  -48.682 -155.239 1.00 67.27  ? 73  GLN A N   1 
ATOM 518  C CA  . GLN A 1 73  ? 38.690  -49.624 -154.940 1.00 64.93  ? 73  GLN A CA  1 
ATOM 519  C C   . GLN A 1 73  ? 38.153  -51.046 -154.932 1.00 70.85  ? 73  GLN A C   1 
ATOM 520  O O   . GLN A 1 73  ? 36.963  -51.281 -154.720 1.00 83.54  ? 73  GLN A O   1 
ATOM 521  C CB  . GLN A 1 73  ? 39.345  -49.319 -153.591 1.00 68.23  ? 73  GLN A CB  1 
ATOM 522  C CG  . GLN A 1 73  ? 40.754  -49.855 -153.456 1.00 73.15  ? 73  GLN A CG  1 
ATOM 523  C CD  . GLN A 1 73  ? 41.374  -49.522 -152.123 1.00 78.12  ? 73  GLN A CD  1 
ATOM 524  O OE1 . GLN A 1 73  ? 40.726  -48.947 -151.252 1.00 83.34  ? 73  GLN A OE1 1 
ATOM 525  N NE2 . GLN A 1 73  ? 42.641  -49.879 -151.954 1.00 76.86  ? 73  GLN A NE2 1 
ATOM 526  N N   . LEU A 1 74  ? 39.054  -51.995 -155.166 1.00 65.44  ? 74  LEU A N   1 
ATOM 527  C CA  . LEU A 1 74  ? 38.748  -53.415 -155.084 1.00 63.78  ? 74  LEU A CA  1 
ATOM 528  C C   . LEU A 1 74  ? 39.815  -54.102 -154.248 1.00 66.72  ? 74  LEU A C   1 
ATOM 529  O O   . LEU A 1 74  ? 41.009  -53.872 -154.451 1.00 77.01  ? 74  LEU A O   1 
ATOM 530  C CB  . LEU A 1 74  ? 38.680  -54.055 -156.469 1.00 61.10  ? 74  LEU A CB  1 
ATOM 531  C CG  . LEU A 1 74  ? 38.909  -55.565 -156.519 1.00 60.25  ? 74  LEU A CG  1 
ATOM 532  C CD1 . LEU A 1 74  ? 37.763  -56.303 -155.870 1.00 63.72  ? 74  LEU A CD1 1 
ATOM 533  C CD2 . LEU A 1 74  ? 39.100  -56.035 -157.943 1.00 67.07  ? 74  LEU A CD2 1 
ATOM 534  N N   . TYR A 1 75  ? 39.381  -54.943 -153.319 1.00 68.29  ? 75  TYR A N   1 
ATOM 535  C CA  . TYR A 1 75  ? 40.280  -55.730 -152.491 1.00 67.17  ? 75  TYR A CA  1 
ATOM 536  C C   . TYR A 1 75  ? 40.307  -57.160 -153.007 1.00 72.79  ? 75  TYR A C   1 
ATOM 537  O O   . TYR A 1 75  ? 39.261  -57.717 -153.352 1.00 75.48  ? 75  TYR A O   1 
ATOM 538  C CB  . TYR A 1 75  ? 39.832  -55.707 -151.031 1.00 67.57  ? 75  TYR A CB  1 
ATOM 539  C CG  . TYR A 1 75  ? 40.143  -54.419 -150.320 1.00 72.70  ? 75  TYR A CG  1 
ATOM 540  C CD1 . TYR A 1 75  ? 41.442  -53.957 -150.230 1.00 78.73  ? 75  TYR A CD1 1 
ATOM 541  C CD2 . TYR A 1 75  ? 39.139  -53.667 -149.738 1.00 73.85  ? 75  TYR A CD2 1 
ATOM 542  C CE1 . TYR A 1 75  ? 41.736  -52.782 -149.581 1.00 78.72  ? 75  TYR A CE1 1 
ATOM 543  C CE2 . TYR A 1 75  ? 39.422  -52.490 -149.088 1.00 76.29  ? 75  TYR A CE2 1 
ATOM 544  C CZ  . TYR A 1 75  ? 40.723  -52.052 -149.013 1.00 79.09  ? 75  TYR A CZ  1 
ATOM 545  O OH  . TYR A 1 75  ? 41.016  -50.877 -148.364 1.00 80.20  ? 75  TYR A OH  1 
ATOM 546  N N   . ILE A 1 76  ? 41.496  -57.750 -153.063 1.00 74.42  ? 76  ILE A N   1 
ATOM 547  C CA  . ILE A 1 76  ? 41.668  -59.133 -153.485 1.00 72.35  ? 76  ILE A CA  1 
ATOM 548  C C   . ILE A 1 76  ? 42.235  -59.913 -152.312 1.00 74.03  ? 76  ILE A C   1 
ATOM 549  O O   . ILE A 1 76  ? 43.273  -59.541 -151.752 1.00 74.38  ? 76  ILE A O   1 
ATOM 550  C CB  . ILE A 1 76  ? 42.577  -59.247 -154.713 1.00 70.89  ? 76  ILE A CB  1 
ATOM 551  C CG1 . ILE A 1 76  ? 41.949  -58.519 -155.897 1.00 72.47  ? 76  ILE A CG1 1 
ATOM 552  C CG2 . ILE A 1 76  ? 42.809  -60.699 -155.055 1.00 72.73  ? 76  ILE A CG2 1 
ATOM 553  C CD1 . ILE A 1 76  ? 42.680  -58.727 -157.193 1.00 75.01  ? 76  ILE A CD1 1 
ATOM 554  N N   . GLY A 1 77  ? 41.553  -60.988 -151.938 1.00 81.07  ? 77  GLY A N   1 
ATOM 555  C CA  . GLY A 1 77  ? 41.961  -61.817 -150.818 1.00 78.08  ? 77  GLY A CA  1 
ATOM 556  C C   . GLY A 1 77  ? 42.663  -63.072 -151.306 1.00 81.09  ? 77  GLY A C   1 
ATOM 557  O O   . GLY A 1 77  ? 42.329  -63.614 -152.357 1.00 83.23  ? 77  GLY A O   1 
ATOM 558  N N   . ARG A 1 78  ? 43.640  -63.522 -150.526 1.00 98.31  ? 78  ARG A N   1 
ATOM 559  C CA  . ARG A 1 78  ? 44.445  -64.683 -150.868 1.00 95.11  ? 78  ARG A CA  1 
ATOM 560  C C   . ARG A 1 78  ? 44.131  -65.824 -149.913 1.00 97.30  ? 78  ARG A C   1 
ATOM 561  O O   . ARG A 1 78  ? 44.189  -65.654 -148.692 1.00 101.11 ? 78  ARG A O   1 
ATOM 562  C CB  . ARG A 1 78  ? 45.935  -64.349 -150.816 1.00 90.56  ? 78  ARG A CB  1 
ATOM 563  C CG  . ARG A 1 78  ? 46.827  -65.570 -150.818 1.00 94.30  ? 78  ARG A CG  1 
ATOM 564  C CD  . ARG A 1 78  ? 48.291  -65.189 -150.864 1.00 100.34 ? 78  ARG A CD  1 
ATOM 565  N NE  . ARG A 1 78  ? 48.767  -64.685 -149.583 1.00 103.44 ? 78  ARG A NE  1 
ATOM 566  C CZ  . ARG A 1 78  ? 49.081  -65.450 -148.547 1.00 102.56 ? 78  ARG A CZ  1 
ATOM 567  N NH1 . ARG A 1 78  ? 48.949  -66.765 -148.595 1.00 96.66  ? 78  ARG A NH1 1 
ATOM 568  N NH2 . ARG A 1 78  ? 49.539  -64.881 -147.437 1.00 105.05 ? 78  ARG A NH2 1 
ATOM 569  N N   . ARG A 1 79  ? 43.798  -66.979 -150.474 1.00 97.87  ? 79  ARG A N   1 
ATOM 570  C CA  . ARG A 1 79  ? 43.551  -68.181 -149.696 1.00 99.29  ? 79  ARG A CA  1 
ATOM 571  C C   . ARG A 1 79  ? 44.850  -68.942 -149.473 1.00 105.56 ? 79  ARG A C   1 
ATOM 572  O O   . ARG A 1 79  ? 45.747  -68.940 -150.319 1.00 107.23 ? 79  ARG A O   1 
ATOM 573  C CB  . ARG A 1 79  ? 42.547  -69.085 -150.407 1.00 98.78  ? 79  ARG A CB  1 
ATOM 574  C CG  . ARG A 1 79  ? 41.142  -69.007 -149.875 1.00 95.21  ? 79  ARG A CG  1 
ATOM 575  C CD  . ARG A 1 79  ? 40.242  -69.916 -150.676 1.00 96.12  ? 79  ARG A CD  1 
ATOM 576  N NE  . ARG A 1 79  ? 39.901  -71.113 -149.920 1.00 95.99  ? 79  ARG A NE  1 
ATOM 577  C CZ  . ARG A 1 79  ? 39.385  -72.211 -150.454 1.00 102.36 ? 79  ARG A CZ  1 
ATOM 578  N NH1 . ARG A 1 79  ? 39.135  -72.297 -151.749 1.00 102.20 ? 79  ARG A NH1 1 
ATOM 579  N NH2 . ARG A 1 79  ? 39.120  -73.250 -149.669 1.00 106.43 ? 79  ARG A NH2 1 
ATOM 580  N N   . THR A 1 80  ? 44.941  -69.608 -148.325 1.00 108.10 ? 80  THR A N   1 
ATOM 581  C CA  . THR A 1 80  ? 46.099  -70.443 -148.043 1.00 105.40 ? 80  THR A CA  1 
ATOM 582  C C   . THR A 1 80  ? 46.033  -71.693 -148.907 1.00 107.41 ? 80  THR A C   1 
ATOM 583  O O   . THR A 1 80  ? 45.116  -72.506 -148.761 1.00 104.94 ? 80  THR A O   1 
ATOM 584  C CB  . THR A 1 80  ? 46.144  -70.819 -146.566 1.00 101.50 ? 80  THR A CB  1 
ATOM 585  O OG1 . THR A 1 80  ? 44.884  -71.379 -146.181 1.00 103.02 ? 80  THR A OG1 1 
ATOM 586  C CG2 . THR A 1 80  ? 46.419  -69.595 -145.717 1.00 102.69 ? 80  THR A CG2 1 
ATOM 587  N N   . MET A 1 81  ? 47.000  -71.849 -149.804 1.00 111.55 ? 81  MET A N   1 
ATOM 588  C CA  . MET A 1 81  ? 46.992  -72.936 -150.768 1.00 111.35 ? 81  MET A CA  1 
ATOM 589  C C   . MET A 1 81  ? 48.143  -73.893 -150.493 1.00 107.41 ? 81  MET A C   1 
ATOM 590  O O   . MET A 1 81  ? 49.272  -73.473 -150.232 1.00 104.03 ? 81  MET A O   1 
ATOM 591  C CB  . MET A 1 81  ? 47.088  -72.405 -152.203 1.00 105.50 ? 81  MET A CB  1 
ATOM 592  N N   . GLN A 1 82  ? 47.844  -75.186 -150.560 1.00 112.94 ? 82  GLN A N   1 
ATOM 593  C CA  . GLN A 1 82  ? 48.843  -76.230 -150.407 1.00 112.63 ? 82  GLN A CA  1 
ATOM 594  C C   . GLN A 1 82  ? 49.336  -76.674 -151.776 1.00 119.09 ? 82  GLN A C   1 
ATOM 595  O O   . GLN A 1 82  ? 48.779  -76.306 -152.813 1.00 122.43 ? 82  GLN A O   1 
ATOM 596  C CB  . GLN A 1 82  ? 48.285  -77.436 -149.652 1.00 111.59 ? 82  GLN A CB  1 
ATOM 597  C CG  . GLN A 1 82  ? 47.365  -78.302 -150.487 1.00 114.30 ? 82  GLN A CG  1 
ATOM 598  C CD  . GLN A 1 82  ? 46.751  -79.431 -149.689 1.00 115.02 ? 82  GLN A CD  1 
ATOM 599  O OE1 . GLN A 1 82  ? 47.058  -79.614 -148.512 1.00 114.08 ? 82  GLN A OE1 1 
ATOM 600  N NE2 . GLN A 1 82  ? 45.877  -80.197 -150.328 1.00 116.22 ? 82  GLN A NE2 1 
ATOM 601  N N   . TYR A 1 83  ? 50.395  -77.475 -151.767 1.00 123.32 ? 83  TYR A N   1 
ATOM 602  C CA  . TYR A 1 83  ? 51.015  -77.971 -152.986 1.00 122.15 ? 83  TYR A CA  1 
ATOM 603  C C   . TYR A 1 83  ? 51.300  -79.455 -152.843 1.00 122.23 ? 83  TYR A C   1 
ATOM 604  O O   . TYR A 1 83  ? 51.733  -79.908 -151.779 1.00 123.29 ? 83  TYR A O   1 
ATOM 605  C CB  . TYR A 1 83  ? 52.305  -77.216 -153.286 1.00 120.84 ? 83  TYR A CB  1 
ATOM 606  C CG  . TYR A 1 83  ? 52.157  -75.715 -153.268 1.00 121.42 ? 83  TYR A CG  1 
ATOM 607  C CD1 . TYR A 1 83  ? 52.297  -75.002 -152.090 1.00 119.25 ? 83  TYR A CD1 1 
ATOM 608  C CD2 . TYR A 1 83  ? 51.868  -75.014 -154.426 1.00 122.14 ? 83  TYR A CD2 1 
ATOM 609  C CE1 . TYR A 1 83  ? 52.159  -73.636 -152.068 1.00 121.31 ? 83  TYR A CE1 1 
ATOM 610  C CE2 . TYR A 1 83  ? 51.734  -73.645 -154.413 1.00 121.48 ? 83  TYR A CE2 1 
ATOM 611  C CZ  . TYR A 1 83  ? 51.880  -72.961 -153.230 1.00 122.05 ? 83  TYR A CZ  1 
ATOM 612  O OH  . TYR A 1 83  ? 51.744  -71.594 -153.207 1.00 125.13 ? 83  TYR A OH  1 
ATOM 613  N N   . THR A 1 84  ? 51.058  -80.206 -153.910 1.00 137.28 ? 84  THR A N   1 
ATOM 614  C CA  . THR A 1 84  ? 51.355  -81.635 -153.961 1.00 139.74 ? 84  THR A CA  1 
ATOM 615  C C   . THR A 1 84  ? 52.370  -81.852 -155.077 1.00 141.06 ? 84  THR A C   1 
ATOM 616  O O   . THR A 1 84  ? 52.030  -81.777 -156.262 1.00 139.68 ? 84  THR A O   1 
ATOM 617  C CB  . THR A 1 84  ? 50.088  -82.454 -154.181 1.00 138.00 ? 84  THR A CB  1 
ATOM 618  O OG1 . THR A 1 84  ? 49.148  -82.161 -153.144 1.00 138.70 ? 84  THR A OG1 1 
ATOM 619  C CG2 . THR A 1 84  ? 50.407  -83.937 -154.151 1.00 138.40 ? 84  THR A CG2 1 
ATOM 620  N N   . VAL A 1 85  ? 53.610  -82.108 -154.703 1.00 145.18 ? 85  VAL A N   1 
ATOM 621  C CA  . VAL A 1 85  ? 54.685  -82.315 -155.663 1.00 143.96 ? 85  VAL A CA  1 
ATOM 622  C C   . VAL A 1 85  ? 54.692  -83.771 -156.100 1.00 144.34 ? 85  VAL A C   1 
ATOM 623  O O   . VAL A 1 85  ? 54.645  -84.687 -155.271 1.00 142.23 ? 85  VAL A O   1 
ATOM 624  C CB  . VAL A 1 85  ? 56.042  -81.902 -155.065 1.00 142.27 ? 85  VAL A CB  1 
ATOM 625  C CG1 . VAL A 1 85  ? 57.178  -82.468 -155.893 1.00 144.61 ? 85  VAL A CG1 1 
ATOM 626  C CG2 . VAL A 1 85  ? 56.141  -80.391 -154.996 1.00 142.35 ? 85  VAL A CG2 1 
ATOM 627  N N   . SER A 1 86  ? 54.714  -83.999 -157.410 1.00 151.07 ? 86  SER A N   1 
ATOM 628  C CA  . SER A 1 86  ? 54.807  -85.388 -157.908 1.00 149.98 ? 86  SER A CA  1 
ATOM 629  C C   . SER A 1 86  ? 56.070  -85.536 -158.754 1.00 152.46 ? 86  SER A C   1 
ATOM 630  O O   . SER A 1 86  ? 56.796  -84.531 -158.936 1.00 150.97 ? 86  SER A O   1 
ATOM 631  C CB  . SER A 1 86  ? 53.571  -85.741 -158.692 1.00 148.92 ? 86  SER A CB  1 
ATOM 632  N N   . ILE A 1 87  ? 56.320  -86.746 -159.260 1.00 159.05 ? 87  ILE A N   1 
ATOM 633  C CA  . ILE A 1 87  ? 57.539  -87.015 -160.060 1.00 156.76 ? 87  ILE A CA  1 
ATOM 634  C C   . ILE A 1 87  ? 57.246  -87.780 -161.357 1.00 158.07 ? 87  ILE A C   1 
ATOM 635  O O   . ILE A 1 87  ? 57.981  -87.490 -162.322 1.00 158.04 ? 87  ILE A O   1 
ATOM 636  C CB  . ILE A 1 87  ? 58.535  -87.767 -159.208 1.00 153.70 ? 87  ILE A CB  1 
ATOM 637  N N   . PRO A 1 88  ? 56.239  -88.680 -161.489 1.00 161.35 ? 88  PRO A N   1 
ATOM 638  C CA  . PRO A 1 88  ? 56.040  -89.505 -162.672 1.00 161.50 ? 88  PRO A CA  1 
ATOM 639  C C   . PRO A 1 88  ? 57.149  -89.577 -163.712 1.00 162.28 ? 88  PRO A C   1 
ATOM 640  O O   . PRO A 1 88  ? 56.934  -89.066 -164.830 1.00 161.68 ? 88  PRO A O   1 
ATOM 641  C CB  . PRO A 1 88  ? 54.802  -88.747 -163.143 1.00 159.14 ? 88  PRO A CB  1 
ATOM 642  C CG  . PRO A 1 88  ? 54.023  -88.566 -161.848 1.00 159.12 ? 88  PRO A CG  1 
ATOM 643  C CD  . PRO A 1 88  ? 55.022  -88.830 -160.718 1.00 159.86 ? 88  PRO A CD  1 
ATOM 644  N N   . ASP A 1 89  ? 58.269  -90.226 -163.367 1.00 169.00 ? 89  ASP A N   1 
ATOM 645  C CA  . ASP A 1 89  ? 59.396  -90.422 -164.311 1.00 167.33 ? 89  ASP A CA  1 
ATOM 646  C C   . ASP A 1 89  ? 60.453  -91.312 -163.653 1.00 168.52 ? 89  ASP A C   1 
ATOM 647  O O   . ASP A 1 89  ? 60.706  -92.405 -164.199 1.00 169.28 ? 89  ASP A O   1 
ATOM 648  C CB  . ASP A 1 89  ? 59.980  -89.093 -164.718 1.00 167.26 ? 89  ASP A CB  1 
ATOM 649  N N   . THR A 1 90  ? 61.045  -90.865 -162.536 1.00 176.66 ? 90  THR A N   1 
ATOM 650  C CA  . THR A 1 90  ? 62.079  -91.639 -161.801 1.00 177.03 ? 90  THR A CA  1 
ATOM 651  C C   . THR A 1 90  ? 63.188  -92.099 -162.750 1.00 179.02 ? 90  THR A C   1 
ATOM 652  O O   . THR A 1 90  ? 63.194  -93.288 -163.129 1.00 180.74 ? 90  THR A O   1 
ATOM 653  C CB  . THR A 1 90  ? 61.443  -92.809 -161.096 1.00 176.67 ? 90  THR A CB  1 
ATOM 654  N N   . VAL A 1 91  ? 64.122  -91.205 -163.088 1.00 184.38 ? 91  VAL A N   1 
ATOM 655  C CA  . VAL A 1 91  ? 65.186  -91.557 -164.060 1.00 185.22 ? 91  VAL A CA  1 
ATOM 656  C C   . VAL A 1 91  ? 66.521  -90.921 -163.663 1.00 187.02 ? 91  VAL A C   1 
ATOM 657  O O   . VAL A 1 91  ? 66.756  -89.751 -164.040 1.00 186.81 ? 91  VAL A O   1 
ATOM 658  C CB  . VAL A 1 91  ? 64.762  -91.128 -165.444 1.00 183.09 ? 91  VAL A CB  1 
ATOM 659  N N   . ALA A 1 92  ? 67.372  -91.669 -162.953 1.00 183.75 ? 92  ALA A N   1 
ATOM 660  C CA  . ALA A 1 92  ? 68.685  -91.152 -162.486 1.00 180.57 ? 92  ALA A CA  1 
ATOM 661  C C   . ALA A 1 92  ? 68.506  -89.771 -161.855 1.00 180.42 ? 92  ALA A C   1 
ATOM 662  O O   . ALA A 1 92  ? 67.525  -89.554 -161.111 1.00 180.17 ? 92  ALA A O   1 
ATOM 663  C CB  . ALA A 1 92  ? 69.690  -91.116 -163.621 1.00 178.22 ? 92  ALA A CB  1 
ATOM 664  N N   . GLU A 1 93  ? 69.449  -88.870 -162.124 1.00 169.11 ? 93  GLU A N   1 
ATOM 665  C CA  . GLU A 1 93  ? 69.358  -87.506 -161.563 1.00 168.40 ? 93  GLU A CA  1 
ATOM 666  C C   . GLU A 1 93  ? 68.796  -86.570 -162.622 1.00 169.26 ? 93  GLU A C   1 
ATOM 667  O O   . GLU A 1 93  ? 67.809  -85.874 -162.324 1.00 168.62 ? 93  GLU A O   1 
ATOM 668  C CB  . GLU A 1 93  ? 70.714  -87.035 -161.089 1.00 164.96 ? 93  GLU A CB  1 
ATOM 669  N N   . GLY A 1 94  ? 69.373  -86.589 -163.825 1.00 162.07 ? 94  GLY A N   1 
ATOM 670  C CA  . GLY A 1 94  ? 68.937  -85.605 -164.829 1.00 159.64 ? 94  GLY A CA  1 
ATOM 671  C C   . GLY A 1 94  ? 68.966  -84.263 -164.147 1.00 160.13 ? 94  GLY A C   1 
ATOM 672  O O   . GLY A 1 94  ? 70.066  -83.685 -164.042 1.00 158.76 ? 94  GLY A O   1 
ATOM 673  N N   . SER A 1 95  ? 67.820  -83.786 -163.664 1.00 151.80 ? 95  SER A N   1 
ATOM 674  C CA  . SER A 1 95  ? 67.823  -82.547 -162.859 1.00 149.38 ? 95  SER A CA  1 
ATOM 675  C C   . SER A 1 95  ? 66.994  -82.814 -161.606 1.00 149.14 ? 95  SER A C   1 
ATOM 676  O O   . SER A 1 95  ? 67.486  -82.507 -160.519 1.00 147.74 ? 95  SER A O   1 
ATOM 677  C CB  . SER A 1 95  ? 67.297  -81.382 -163.656 1.00 146.90 ? 95  SER A CB  1 
ATOM 678  N N   . GLU A 1 96  ? 65.816  -83.426 -161.763 1.00 144.56 ? 96  GLU A N   1 
ATOM 679  C CA  . GLU A 1 96  ? 64.935  -83.717 -160.609 1.00 142.85 ? 96  GLU A CA  1 
ATOM 680  C C   . GLU A 1 96  ? 65.201  -82.684 -159.518 1.00 144.50 ? 96  GLU A C   1 
ATOM 681  O O   . GLU A 1 96  ? 65.747  -83.088 -158.470 1.00 143.24 ? 96  GLU A O   1 
ATOM 682  C CB  . GLU A 1 96  ? 65.192  -85.117 -160.106 1.00 139.07 ? 96  GLU A CB  1 
ATOM 683  N N   . TYR A 1 97  ? 64.824  -81.418 -159.748 1.00 148.14 ? 97  TYR A N   1 
ATOM 684  C CA  . TYR A 1 97  ? 65.168  -80.364 -158.766 1.00 146.02 ? 97  TYR A CA  1 
ATOM 685  C C   . TYR A 1 97  ? 64.451  -79.039 -158.996 1.00 145.77 ? 97  TYR A C   1 
ATOM 686  O O   . TYR A 1 97  ? 63.286  -79.034 -159.440 1.00 146.10 ? 97  TYR A O   1 
ATOM 687  C CB  . TYR A 1 97  ? 66.640  -80.098 -158.858 1.00 146.06 ? 97  TYR A CB  1 
ATOM 688  N N   . SER A 1 98  ? 65.145  -77.947 -158.676 1.00 142.07 ? 98  SER A N   1 
ATOM 689  C CA  . SER A 1 98  ? 64.607  -76.599 -158.823 1.00 144.89 ? 98  SER A CA  1 
ATOM 690  C C   . SER A 1 98  ? 63.261  -76.409 -158.139 1.00 147.04 ? 98  SER A C   1 
ATOM 691  O O   . SER A 1 98  ? 62.439  -75.625 -158.624 1.00 147.20 ? 98  SER A O   1 
ATOM 692  C CB  . SER A 1 98  ? 64.490  -76.196 -160.298 1.00 143.69 ? 98  SER A CB  1 
ATOM 693  N N   . LEU A 1 99  ? 63.012  -77.095 -157.019 1.00 135.10 ? 99  LEU A N   1 
ATOM 694  C CA  . LEU A 1 99  ? 61.745  -76.919 -156.318 1.00 130.28 ? 99  LEU A CA  1 
ATOM 695  C C   . LEU A 1 99  ? 61.561  -75.484 -155.842 1.00 132.27 ? 99  LEU A C   1 
ATOM 696  O O   . LEU A 1 99  ? 60.482  -74.907 -156.023 1.00 135.10 ? 99  LEU A O   1 
ATOM 697  C CB  . LEU A 1 99  ? 61.655  -77.887 -155.139 1.00 125.19 ? 99  LEU A CB  1 
ATOM 698  N N   . THR A 1 100 ? 62.599  -74.892 -155.253 1.00 126.99 ? 100 THR A N   1 
ATOM 699  C CA  . THR A 1 100 ? 62.584  -73.500 -154.813 1.00 125.11 ? 100 THR A CA  1 
ATOM 700  C C   . THR A 1 100 ? 61.412  -73.195 -153.889 1.00 126.69 ? 100 THR A C   1 
ATOM 701  O O   . THR A 1 100 ? 60.557  -72.370 -154.220 1.00 128.47 ? 100 THR A O   1 
ATOM 702  C CB  . THR A 1 100 ? 62.557  -72.559 -156.020 1.00 121.86 ? 100 THR A CB  1 
ATOM 703  N N   . VAL A 1 101 ? 61.361  -73.851 -152.732 1.00 119.20 ? 101 VAL A N   1 
ATOM 704  C CA  . VAL A 1 101 ? 60.328  -73.554 -151.749 1.00 116.65 ? 101 VAL A CA  1 
ATOM 705  C C   . VAL A 1 101 ? 60.525  -72.148 -151.199 1.00 120.99 ? 101 VAL A C   1 
ATOM 706  O O   . VAL A 1 101 ? 61.438  -71.910 -150.404 1.00 124.44 ? 101 VAL A O   1 
ATOM 707  C CB  . VAL A 1 101 ? 60.345  -74.581 -150.617 1.00 113.12 ? 101 VAL A CB  1 
ATOM 708  N N   . ALA A 1 102 ? 59.671  -71.212 -151.609 1.00 117.39 ? 102 ALA A N   1 
ATOM 709  C CA  . ALA A 1 102 ? 59.854  -69.810 -151.261 1.00 113.24 ? 102 ALA A CA  1 
ATOM 710  C C   . ALA A 1 102 ? 59.660  -69.558 -149.772 1.00 114.91 ? 102 ALA A C   1 
ATOM 711  O O   . ALA A 1 102 ? 60.569  -69.057 -149.105 1.00 120.54 ? 102 ALA A O   1 
ATOM 712  C CB  . ALA A 1 102 ? 58.896  -68.931 -152.065 1.00 112.18 ? 102 ALA A CB  1 
ATOM 713  N N   . ILE A 1 103 ? 58.477  -69.884 -149.251 1.00 113.21 ? 103 ILE A N   1 
ATOM 714  C CA  . ILE A 1 103 ? 58.112  -69.626 -147.860 1.00 114.70 ? 103 ILE A CA  1 
ATOM 715  C C   . ILE A 1 103 ? 58.050  -68.132 -147.568 1.00 116.55 ? 103 ILE A C   1 
ATOM 716  O O   . ILE A 1 103 ? 58.540  -67.312 -148.351 1.00 114.16 ? 103 ILE A O   1 
ATOM 717  C CB  . ILE A 1 103 ? 59.077  -70.318 -146.892 1.00 111.12 ? 103 ILE A CB  1 
ATOM 718  N N   . GLY A 1 104 ? 57.441  -67.770 -146.444 1.00 115.89 ? 104 GLY A N   1 
ATOM 719  C CA  . GLY A 1 104 ? 57.220  -66.380 -146.117 1.00 112.55 ? 104 GLY A CA  1 
ATOM 720  C C   . GLY A 1 104 ? 58.508  -65.644 -145.809 1.00 113.00 ? 104 GLY A C   1 
ATOM 721  O O   . GLY A 1 104 ? 59.589  -66.219 -145.682 1.00 112.86 ? 104 GLY A O   1 
ATOM 722  N N   . GLY A 1 105 ? 58.380  -64.326 -145.697 1.00 112.35 ? 105 GLY A N   1 
ATOM 723  C CA  . GLY A 1 105 ? 59.519  -63.490 -145.381 1.00 113.38 ? 105 GLY A CA  1 
ATOM 724  C C   . GLY A 1 105 ? 60.260  -63.002 -146.607 1.00 114.03 ? 105 GLY A C   1 
ATOM 725  O O   . GLY A 1 105 ? 60.495  -61.800 -146.761 1.00 110.67 ? 105 GLY A O   1 
ATOM 726  N N   . GLY A 1 106 ? 60.633  -63.924 -147.489 1.00 120.38 ? 106 GLY A N   1 
ATOM 727  C CA  . GLY A 1 106 ? 61.350  -63.560 -148.694 1.00 118.51 ? 106 GLY A CA  1 
ATOM 728  C C   . GLY A 1 106 ? 62.461  -64.525 -149.055 1.00 120.05 ? 106 GLY A C   1 
ATOM 729  O O   . GLY A 1 106 ? 63.206  -64.289 -150.010 1.00 120.75 ? 106 GLY A O   1 
ATOM 730  N N   . VAL A 1 107 ? 62.581  -65.615 -148.302 1.00 118.44 ? 107 VAL A N   1 
ATOM 731  C CA  . VAL A 1 107 ? 63.597  -66.616 -148.586 1.00 119.36 ? 107 VAL A CA  1 
ATOM 732  C C   . VAL A 1 107 ? 63.260  -67.351 -149.882 1.00 123.52 ? 107 VAL A C   1 
ATOM 733  O O   . VAL A 1 107 ? 62.123  -67.341 -150.360 1.00 125.19 ? 107 VAL A O   1 
ATOM 734  C CB  . VAL A 1 107 ? 63.717  -67.590 -147.418 1.00 115.69 ? 107 VAL A CB  1 
ATOM 735  N N   . SER A 1 108 ? 64.274  -67.965 -150.491 1.00 123.66 ? 108 SER A N   1 
ATOM 736  C CA  . SER A 1 108 ? 64.011  -68.840 -151.627 1.00 122.18 ? 108 SER A CA  1 
ATOM 737  C C   . SER A 1 108 ? 64.574  -70.236 -151.396 1.00 124.33 ? 108 SER A C   1 
ATOM 738  O O   . SER A 1 108 ? 63.860  -71.229 -151.571 1.00 127.05 ? 108 SER A O   1 
ATOM 739  C CB  . SER A 1 108 ? 64.590  -68.241 -152.910 1.00 120.55 ? 108 SER A CB  1 
ATOM 740  N N   . GLN A 1 109 ? 65.842  -70.313 -150.972 1.00 123.50 ? 109 GLN A N   1 
ATOM 741  C CA  . GLN A 1 109 ? 66.576  -71.550 -150.708 1.00 121.08 ? 109 GLN A CA  1 
ATOM 742  C C   . GLN A 1 109 ? 66.216  -72.649 -151.701 1.00 125.34 ? 109 GLN A C   1 
ATOM 743  O O   . GLN A 1 109 ? 65.575  -73.638 -151.324 1.00 123.26 ? 109 GLN A O   1 
ATOM 744  C CB  . GLN A 1 109 ? 66.322  -72.027 -149.280 1.00 117.55 ? 109 GLN A CB  1 
ATOM 745  N N   . PRO A 1 110 ? 66.597  -72.511 -152.974 1.00 123.71 ? 110 PRO A N   1 
ATOM 746  C CA  . PRO A 1 110 ? 66.139  -73.467 -153.992 1.00 119.76 ? 110 PRO A CA  1 
ATOM 747  C C   . PRO A 1 110 ? 66.643  -74.885 -153.769 1.00 117.49 ? 110 PRO A C   1 
ATOM 748  O O   . PRO A 1 110 ? 67.377  -75.156 -152.815 1.00 114.54 ? 110 PRO A O   1 
ATOM 749  C CB  . PRO A 1 110 ? 66.693  -72.875 -155.293 1.00 117.91 ? 110 PRO A CB  1 
ATOM 750  C CG  . PRO A 1 110 ? 67.882  -72.091 -154.859 1.00 118.13 ? 110 PRO A CG  1 
ATOM 751  C CD  . PRO A 1 110 ? 67.485  -71.487 -153.546 1.00 116.70 ? 110 PRO A CD  1 
ATOM 752  N N   . PHE A 1 111 ? 66.243  -75.798 -154.650 1.00 132.44 ? 111 PHE A N   1 
ATOM 753  C CA  . PHE A 1 111 ? 66.584  -77.206 -154.529 1.00 135.36 ? 111 PHE A CA  1 
ATOM 754  C C   . PHE A 1 111 ? 67.420  -77.640 -155.724 1.00 136.31 ? 111 PHE A C   1 
ATOM 755  O O   . PHE A 1 111 ? 67.306  -77.093 -156.823 1.00 134.32 ? 111 PHE A O   1 
ATOM 756  C CB  . PHE A 1 111 ? 65.327  -78.075 -154.421 1.00 134.30 ? 111 PHE A CB  1 
ATOM 757  N N   . GLN A 1 112 ? 68.263  -78.646 -155.495 1.00 140.23 ? 112 GLN A N   1 
ATOM 758  C CA  . GLN A 1 112 ? 69.166  -79.162 -156.512 1.00 138.26 ? 112 GLN A CA  1 
ATOM 759  C C   . GLN A 1 112 ? 68.915  -80.649 -156.711 1.00 139.41 ? 112 GLN A C   1 
ATOM 760  O O   . GLN A 1 112 ? 68.139  -81.273 -155.983 1.00 137.67 ? 112 GLN A O   1 
ATOM 761  C CB  . GLN A 1 112 ? 70.635  -78.922 -156.141 1.00 133.65 ? 112 GLN A CB  1 
ATOM 762  N N   . TYR A 1 113 ? 69.581  -81.205 -157.725 1.00 144.71 ? 113 TYR A N   1 
ATOM 763  C CA  . TYR A 1 113 ? 69.415  -82.603 -158.109 1.00 143.25 ? 113 TYR A CA  1 
ATOM 764  C C   . TYR A 1 113 ? 69.621  -83.529 -156.920 1.00 144.98 ? 113 TYR A C   1 
ATOM 765  O O   . TYR A 1 113 ? 70.709  -83.569 -156.338 1.00 145.43 ? 113 TYR A O   1 
ATOM 766  C CB  . TYR A 1 113 ? 70.385  -82.967 -159.235 1.00 140.35 ? 113 TYR A CB  1 
ATOM 767  N N   . THR A 1 114 ? 68.585  -84.285 -156.558 1.00 145.01 ? 114 THR A N   1 
ATOM 768  C CA  . THR A 1 114 ? 68.648  -85.085 -155.342 1.00 144.13 ? 114 THR A CA  1 
ATOM 769  C C   . THR A 1 114 ? 69.549  -86.300 -155.520 1.00 145.69 ? 114 THR A C   1 
ATOM 770  O O   . THR A 1 114 ? 70.563  -86.444 -154.829 1.00 144.51 ? 114 THR A O   1 
ATOM 771  C CB  . THR A 1 114 ? 67.241  -85.509 -154.922 1.00 141.90 ? 114 THR A CB  1 
ATOM 772  N N   . ALA A 1 115 ? 69.142  -87.223 -156.399 1.00 151.90 ? 115 ALA A N   1 
ATOM 773  C CA  . ALA A 1 115 ? 69.909  -88.488 -156.472 1.00 151.36 ? 115 ALA A CA  1 
ATOM 774  C C   . ALA A 1 115 ? 69.687  -89.254 -157.770 1.00 151.17 ? 115 ALA A C   1 
ATOM 775  O O   . ALA A 1 115 ? 69.088  -88.694 -158.702 1.00 149.38 ? 115 ALA A O   1 
ATOM 776  C CB  . ALA A 1 115 ? 69.516  -89.367 -155.305 1.00 148.92 ? 115 ALA A CB  1 
ATOM 777  N N   . LYS A 1 116 ? 70.122  -90.516 -157.784 1.00 164.22 ? 116 LYS A N   1 
ATOM 778  C CA  . LYS A 1 116 ? 70.034  -91.381 -158.979 1.00 163.19 ? 116 LYS A CA  1 
ATOM 779  C C   . LYS A 1 116 ? 70.354  -92.799 -158.517 1.00 162.55 ? 116 LYS A C   1 
ATOM 780  O O   . LYS A 1 116 ? 70.093  -93.087 -157.334 1.00 161.13 ? 116 LYS A O   1 
ATOM 781  C CB  . LYS A 1 116 ? 71.048  -90.930 -159.997 1.00 160.76 ? 116 LYS A CB  1 
ATOM 782  N N   . GLU A 1 117 ? 70.928  -93.628 -159.391 1.00 161.26 ? 117 GLU A N   1 
ATOM 783  C CA  . GLU A 1 117 ? 71.368  -94.987 -158.994 1.00 160.76 ? 117 GLU A CA  1 
ATOM 784  C C   . GLU A 1 117 ? 70.224  -95.770 -158.347 1.00 163.24 ? 117 GLU A C   1 
ATOM 785  O O   . GLU A 1 117 ? 70.199  -95.871 -157.100 1.00 162.72 ? 117 GLU A O   1 
ATOM 786  C CB  . GLU A 1 117 ? 72.548  -94.874 -158.062 1.00 160.12 ? 117 GLU A CB  1 
ATOM 787  N N   . ASN A 1 118 ? 69.326  -96.330 -159.163 1.00 174.02 ? 118 ASN A N   1 
ATOM 788  C CA  . ASN A 1 118 ? 68.185  -97.127 -158.647 1.00 173.89 ? 118 ASN A CA  1 
ATOM 789  C C   . ASN A 1 118 ? 67.403  -96.321 -157.605 1.00 175.02 ? 118 ASN A C   1 
ATOM 790  O O   . ASN A 1 118 ? 67.031  -96.892 -156.558 1.00 172.83 ? 118 ASN A O   1 
ATOM 791  C CB  . ASN A 1 118 ? 68.673  -98.447 -158.090 1.00 170.55 ? 118 ASN A CB  1 
ATOM 792  N N   . ASP A 1 119 ? 67.154  -95.035 -157.881 1.00 173.80 ? 119 ASP A N   1 
ATOM 793  C CA  . ASP A 1 119 ? 66.325  -94.213 -156.965 1.00 171.32 ? 119 ASP A CA  1 
ATOM 794  C C   . ASP A 1 119 ? 64.960  -93.978 -157.610 1.00 171.41 ? 119 ASP A C   1 
ATOM 795  O O   . ASP A 1 119 ? 64.899  -93.554 -158.785 1.00 171.35 ? 119 ASP A O   1 
ATOM 796  C CB  . ASP A 1 119 ? 67.014  -92.911 -156.632 1.00 169.12 ? 119 ASP A CB  1 
ATOM 797  N N   . THR A 1 120 ? 63.896  -94.265 -156.860 1.00 159.00 ? 120 THR A N   1 
ATOM 798  C CA  . THR A 1 120 ? 62.526  -94.081 -157.384 1.00 156.13 ? 120 THR A CA  1 
ATOM 799  C C   . THR A 1 120 ? 61.962  -92.759 -156.881 1.00 157.71 ? 120 THR A C   1 
ATOM 800  O O   . THR A 1 120 ? 62.528  -92.151 -155.953 1.00 159.22 ? 120 THR A O   1 
ATOM 801  C CB  . THR A 1 120 ? 61.646  -95.226 -156.945 1.00 154.21 ? 120 THR A CB  1 
ATOM 802  N N   . ALA A 1 121 ? 60.862  -92.335 -157.487 1.00 160.27 ? 121 ALA A N   1 
ATOM 803  C CA  . ALA A 1 121 ? 60.207  -91.111 -157.037 1.00 161.04 ? 121 ALA A CA  1 
ATOM 804  C C   . ALA A 1 121 ? 60.097  -91.034 -155.520 1.00 161.67 ? 121 ALA A C   1 
ATOM 805  O O   . ALA A 1 121 ? 60.258  -89.953 -154.944 1.00 162.46 ? 121 ALA A O   1 
ATOM 806  C CB  . ALA A 1 121 ? 58.827  -90.992 -157.680 1.00 159.73 ? 121 ALA A CB  1 
ATOM 807  N N   . LEU A 1 122 ? 59.829  -92.161 -154.855 1.00 155.86 ? 122 LEU A N   1 
ATOM 808  C CA  . LEU A 1 122 ? 59.770  -92.157 -153.398 1.00 154.40 ? 122 LEU A CA  1 
ATOM 809  C C   . LEU A 1 122 ? 61.093  -91.705 -152.796 1.00 154.83 ? 122 LEU A C   1 
ATOM 810  O O   . LEU A 1 122 ? 61.121  -90.838 -151.912 1.00 154.12 ? 122 LEU A O   1 
ATOM 811  C CB  . LEU A 1 122 ? 59.402  -93.548 -152.887 1.00 153.08 ? 122 LEU A CB  1 
ATOM 812  C CG  . LEU A 1 122 ? 57.957  -93.993 -153.097 1.00 153.87 ? 122 LEU A CG  1 
ATOM 813  C CD1 . LEU A 1 122 ? 57.886  -95.499 -153.276 1.00 152.90 ? 122 LEU A CD1 1 
ATOM 814  C CD2 . LEU A 1 122 ? 57.091  -93.555 -151.928 1.00 152.67 ? 122 LEU A CD2 1 
ATOM 815  N N   . ILE A 1 123 ? 62.202  -92.267 -153.279 1.00 153.63 ? 123 ILE A N   1 
ATOM 816  C CA  . ILE A 1 123 ? 63.508  -91.929 -152.726 1.00 152.98 ? 123 ILE A CA  1 
ATOM 817  C C   . ILE A 1 123 ? 63.861  -90.470 -152.976 1.00 152.88 ? 123 ILE A C   1 
ATOM 818  O O   . ILE A 1 123 ? 64.329  -89.777 -152.066 1.00 153.08 ? 123 ILE A O   1 
ATOM 819  C CB  . ILE A 1 123 ? 64.579  -92.848 -153.314 1.00 150.25 ? 123 ILE A CB  1 
ATOM 820  N N   . VAL A 1 124 ? 63.642  -89.980 -154.198 1.00 148.08 ? 124 VAL A N   1 
ATOM 821  C CA  . VAL A 1 124 ? 64.032  -88.610 -154.510 1.00 147.26 ? 124 VAL A CA  1 
ATOM 822  C C   . VAL A 1 124 ? 63.154  -87.617 -153.756 1.00 150.04 ? 124 VAL A C   1 
ATOM 823  O O   . VAL A 1 124 ? 63.633  -86.579 -153.289 1.00 150.27 ? 124 VAL A O   1 
ATOM 824  C CB  . VAL A 1 124 ? 64.006  -88.370 -156.032 1.00 148.01 ? 124 VAL A CB  1 
ATOM 825  C CG1 . VAL A 1 124 ? 62.669  -88.729 -156.612 1.00 149.11 ? 124 VAL A CG1 1 
ATOM 826  C CG2 . VAL A 1 124 ? 64.342  -86.928 -156.356 1.00 149.23 ? 124 VAL A CG2 1 
ATOM 827  N N   . LEU A 1 125 ? 61.864  -87.923 -153.604 1.00 157.68 ? 125 LEU A N   1 
ATOM 828  C CA  . LEU A 1 125 ? 60.995  -87.026 -152.848 1.00 157.85 ? 125 LEU A CA  1 
ATOM 829  C C   . LEU A 1 125 ? 61.352  -87.020 -151.368 1.00 157.04 ? 125 LEU A C   1 
ATOM 830  O O   . LEU A 1 125 ? 61.328  -85.967 -150.720 1.00 154.72 ? 125 LEU A O   1 
ATOM 831  C CB  . LEU A 1 125 ? 59.531  -87.409 -153.048 1.00 154.61 ? 125 LEU A CB  1 
ATOM 832  C CG  . LEU A 1 125 ? 58.970  -86.994 -154.404 1.00 153.97 ? 125 LEU A CG  1 
ATOM 833  C CD1 . LEU A 1 125 ? 57.503  -87.338 -154.484 1.00 154.78 ? 125 LEU A CD1 1 
ATOM 834  C CD2 . LEU A 1 125 ? 59.192  -85.514 -154.645 1.00 154.59 ? 125 LEU A CD2 1 
ATOM 835  N N   . ASN A 1 126 ? 61.684  -88.186 -150.808 1.00 150.05 ? 126 ASN A N   1 
ATOM 836  C CA  . ASN A 1 126 ? 62.120  -88.220 -149.418 1.00 146.65 ? 126 ASN A CA  1 
ATOM 837  C C   . ASN A 1 126 ? 63.422  -87.454 -149.241 1.00 147.93 ? 126 ASN A C   1 
ATOM 838  O O   . ASN A 1 126 ? 63.616  -86.766 -148.233 1.00 149.06 ? 126 ASN A O   1 
ATOM 839  C CB  . ASN A 1 126 ? 62.271  -89.667 -148.956 1.00 146.58 ? 126 ASN A CB  1 
ATOM 840  C CG  . ASN A 1 126 ? 60.938  -90.326 -148.691 1.00 147.60 ? 126 ASN A CG  1 
ATOM 841  O OD1 . ASN A 1 126 ? 60.348  -90.153 -147.625 1.00 146.69 ? 126 ASN A OD1 1 
ATOM 842  N ND2 . ASN A 1 126 ? 60.449  -91.081 -149.667 1.00 148.14 ? 126 ASN A ND2 1 
ATOM 843  N N   . GLU A 1 127 ? 64.328  -87.559 -150.216 1.00 148.71 ? 127 GLU A N   1 
ATOM 844  C CA  . GLU A 1 127 ? 65.560  -86.781 -150.176 1.00 149.46 ? 127 GLU A CA  1 
ATOM 845  C C   . GLU A 1 127 ? 65.279  -85.288 -150.237 1.00 148.97 ? 127 GLU A C   1 
ATOM 846  O O   . GLU A 1 127 ? 65.928  -84.509 -149.533 1.00 147.31 ? 127 GLU A O   1 
ATOM 847  C CB  . GLU A 1 127 ? 66.481  -87.194 -151.323 1.00 147.13 ? 127 GLU A CB  1 
ATOM 848  N N   . PHE A 1 128 ? 64.327  -84.872 -151.075 1.00 143.87 ? 128 PHE A N   1 
ATOM 849  C CA  . PHE A 1 128 ? 63.949  -83.464 -151.122 1.00 142.91 ? 128 PHE A CA  1 
ATOM 850  C C   . PHE A 1 128 ? 63.377  -83.002 -149.791 1.00 144.72 ? 128 PHE A C   1 
ATOM 851  O O   . PHE A 1 128 ? 63.698  -81.906 -149.314 1.00 144.75 ? 128 PHE A O   1 
ATOM 852  C CB  . PHE A 1 128 ? 62.942  -83.223 -152.245 1.00 141.52 ? 128 PHE A CB  1 
ATOM 853  C CG  . PHE A 1 128 ? 63.569  -82.790 -153.533 1.00 143.44 ? 128 PHE A CG  1 
ATOM 854  C CD1 . PHE A 1 128 ? 64.651  -81.928 -153.527 1.00 144.51 ? 128 PHE A CD1 1 
ATOM 855  C CD2 . PHE A 1 128 ? 63.069  -83.221 -154.747 1.00 143.83 ? 128 PHE A CD2 1 
ATOM 856  C CE1 . PHE A 1 128 ? 65.232  -81.519 -154.705 1.00 143.00 ? 128 PHE A CE1 1 
ATOM 857  C CE2 . PHE A 1 128 ? 63.648  -82.812 -155.930 1.00 145.21 ? 128 PHE A CE2 1 
ATOM 858  C CZ  . PHE A 1 128 ? 64.729  -81.957 -155.905 1.00 144.04 ? 128 PHE A CZ  1 
ATOM 859  N N   . LYS A 1 129 ? 62.524  -83.822 -149.178 1.00 146.72 ? 129 LYS A N   1 
ATOM 860  C CA  . LYS A 1 129 ? 61.965  -83.469 -147.879 1.00 145.50 ? 129 LYS A CA  1 
ATOM 861  C C   . LYS A 1 129 ? 63.067  -83.319 -146.840 1.00 145.92 ? 129 LYS A C   1 
ATOM 862  O O   . LYS A 1 129 ? 63.081  -82.356 -146.064 1.00 143.90 ? 129 LYS A O   1 
ATOM 863  C CB  . LYS A 1 129 ? 60.951  -84.526 -147.440 1.00 142.81 ? 129 LYS A CB  1 
ATOM 864  N N   . SER A 1 130 ? 64.010  -84.262 -146.824 1.00 147.53 ? 130 SER A N   1 
ATOM 865  C CA  . SER A 1 130 ? 65.108  -84.202 -145.866 1.00 146.36 ? 130 SER A CA  1 
ATOM 866  C C   . SER A 1 130 ? 65.980  -82.977 -146.103 1.00 146.26 ? 130 SER A C   1 
ATOM 867  O O   . SER A 1 130 ? 66.418  -82.325 -145.149 1.00 145.51 ? 130 SER A O   1 
ATOM 868  C CB  . SER A 1 130 ? 65.937  -85.480 -145.949 1.00 144.56 ? 130 SER A CB  1 
ATOM 869  O OG  . SER A 1 130 ? 65.097  -86.613 -146.071 1.00 144.81 ? 130 SER A OG  1 
ATOM 870  N N   . GLN A 1 131 ? 66.248  -82.651 -147.368 1.00 142.73 ? 131 GLN A N   1 
ATOM 871  C CA  . GLN A 1 131 ? 67.049  -81.473 -147.677 1.00 141.74 ? 131 GLN A CA  1 
ATOM 872  C C   . GLN A 1 131 ? 66.347  -80.198 -147.234 1.00 143.67 ? 131 GLN A C   1 
ATOM 873  O O   . GLN A 1 131 ? 66.986  -79.280 -146.707 1.00 141.93 ? 131 GLN A O   1 
ATOM 874  C CB  . GLN A 1 131 ? 67.353  -81.435 -149.174 1.00 141.79 ? 131 GLN A CB  1 
ATOM 875  C CG  . GLN A 1 131 ? 67.603  -80.050 -149.730 1.00 142.35 ? 131 GLN A CG  1 
ATOM 876  C CD  . GLN A 1 131 ? 67.573  -80.028 -151.243 1.00 145.42 ? 131 GLN A CD  1 
ATOM 877  O OE1 . GLN A 1 131 ? 66.725  -79.371 -151.847 1.00 146.78 ? 131 GLN A OE1 1 
ATOM 878  N NE2 . GLN A 1 131 ? 68.503  -80.745 -151.866 1.00 142.40 ? 131 GLN A NE2 1 
ATOM 879  N N   . ILE A 1 132 ? 65.033  -80.121 -147.443 1.00 152.69 ? 132 ILE A N   1 
ATOM 880  C CA  . ILE A 1 132 ? 64.280  -78.943 -147.020 1.00 151.63 ? 132 ILE A CA  1 
ATOM 881  C C   . ILE A 1 132 ? 64.297  -78.818 -145.503 1.00 151.02 ? 132 ILE A C   1 
ATOM 882  O O   . ILE A 1 132 ? 64.512  -77.727 -144.957 1.00 151.14 ? 132 ILE A O   1 
ATOM 883  C CB  . ILE A 1 132 ? 62.846  -78.999 -147.577 1.00 149.59 ? 132 ILE A CB  1 
ATOM 884  C CG1 . ILE A 1 132 ? 62.855  -78.723 -149.082 1.00 149.79 ? 132 ILE A CG1 1 
ATOM 885  C CG2 . ILE A 1 132 ? 61.953  -78.006 -146.857 1.00 148.86 ? 132 ILE A CG2 1 
ATOM 886  C CD1 . ILE A 1 132 ? 63.657  -77.497 -149.474 1.00 147.46 ? 132 ILE A CD1 1 
ATOM 887  N N   . GLU A 1 133 ? 64.082  -79.929 -144.794 1.00 146.64 ? 133 GLU A N   1 
ATOM 888  C CA  . GLU A 1 133 ? 64.145  -79.887 -143.337 1.00 145.89 ? 133 GLU A CA  1 
ATOM 889  C C   . GLU A 1 133 ? 65.541  -79.527 -142.852 1.00 148.66 ? 133 GLU A C   1 
ATOM 890  O O   . GLU A 1 133 ? 65.692  -78.899 -141.798 1.00 147.16 ? 133 GLU A O   1 
ATOM 891  C CB  . GLU A 1 133 ? 63.714  -81.226 -142.742 1.00 144.72 ? 133 GLU A CB  1 
ATOM 892  C CG  . GLU A 1 133 ? 62.348  -81.702 -143.185 1.00 146.20 ? 133 GLU A CG  1 
ATOM 893  C CD  . GLU A 1 133 ? 62.256  -83.213 -143.227 1.00 148.77 ? 133 GLU A CD  1 
ATOM 894  O OE1 . GLU A 1 133 ? 63.316  -83.872 -143.209 1.00 150.40 ? 133 GLU A OE1 1 
ATOM 895  O OE2 . GLU A 1 133 ? 61.129  -83.745 -143.285 1.00 145.92 ? 133 GLU A OE2 1 
ATOM 896  N N   . ALA A 1 134 ? 66.570  -79.912 -143.606 1.00 157.61 ? 134 ALA A N   1 
ATOM 897  C CA  . ALA A 1 134 ? 67.939  -79.603 -143.211 1.00 157.93 ? 134 ALA A CA  1 
ATOM 898  C C   . ALA A 1 134 ? 68.225  -78.107 -143.294 1.00 159.36 ? 134 ALA A C   1 
ATOM 899  O O   . ALA A 1 134 ? 68.961  -77.567 -142.459 1.00 157.23 ? 134 ALA A O   1 
ATOM 900  C CB  . ALA A 1 134 ? 68.923  -80.395 -144.075 1.00 156.83 ? 134 ALA A CB  1 
ATOM 901  N N   . SER A 1 135 ? 67.660  -77.422 -144.282 1.00 158.10 ? 135 SER A N   1 
ATOM 902  C CA  . SER A 1 135 ? 67.931  -75.998 -144.438 1.00 155.44 ? 135 SER A CA  1 
ATOM 903  C C   . SER A 1 135 ? 67.341  -75.228 -143.262 1.00 153.34 ? 135 SER A C   1 
ATOM 904  O O   . SER A 1 135 ? 66.203  -75.496 -142.860 1.00 150.90 ? 135 SER A O   1 
ATOM 905  C CB  . SER A 1 135 ? 67.352  -75.483 -145.749 1.00 152.11 ? 135 SER A CB  1 
ATOM 906  O OG  . SER A 1 135 ? 67.034  -74.104 -145.650 1.00 151.38 ? 135 SER A OG  1 
ATOM 907  N N   . PRO A 1 136 ? 68.064  -74.270 -142.693 1.00 148.67 ? 136 PRO A N   1 
ATOM 908  C CA  . PRO A 1 136 ? 67.572  -73.563 -141.525 1.00 148.37 ? 136 PRO A CA  1 
ATOM 909  C C   . PRO A 1 136 ? 66.766  -72.293 -141.764 1.00 148.58 ? 136 PRO A C   1 
ATOM 910  O O   . PRO A 1 136 ? 66.598  -71.487 -140.844 1.00 146.94 ? 136 PRO A O   1 
ATOM 911  C CB  . PRO A 1 136 ? 68.897  -73.308 -140.790 1.00 147.26 ? 136 PRO A CB  1 
ATOM 912  C CG  . PRO A 1 136 ? 69.912  -73.191 -142.078 1.00 147.82 ? 136 PRO A CG  1 
ATOM 913  C CD  . PRO A 1 136 ? 68.942  -73.191 -143.219 1.00 146.66 ? 136 PRO A CD  1 
ATOM 914  N N   . THR A 1 137 ? 66.258  -72.099 -142.979 1.00 148.10 ? 137 THR A N   1 
ATOM 915  C CA  . THR A 1 137 ? 65.432  -70.945 -143.288 1.00 147.28 ? 137 THR A CA  1 
ATOM 916  C C   . THR A 1 137 ? 63.996  -71.318 -143.608 1.00 146.88 ? 137 THR A C   1 
ATOM 917  O O   . THR A 1 137 ? 63.157  -70.420 -143.744 1.00 144.46 ? 137 THR A O   1 
ATOM 918  C CB  . THR A 1 137 ? 66.022  -70.159 -144.470 1.00 146.07 ? 137 THR A CB  1 
ATOM 919  O OG1 . THR A 1 137 ? 66.404  -71.071 -145.511 1.00 146.63 ? 137 THR A OG1 1 
ATOM 920  C CG2 . THR A 1 137 ? 67.237  -69.367 -144.025 1.00 143.53 ? 137 THR A CG2 1 
ATOM 921  N N   . ILE A 1 138 ? 63.695  -72.608 -143.735 1.00 146.92 ? 138 ILE A N   1 
ATOM 922  C CA  . ILE A 1 138 ? 62.356  -73.050 -144.107 1.00 144.29 ? 138 ILE A CA  1 
ATOM 923  C C   . ILE A 1 138 ? 61.749  -74.033 -143.119 1.00 146.07 ? 138 ILE A C   1 
ATOM 924  O O   . ILE A 1 138 ? 60.513  -74.063 -142.973 1.00 147.28 ? 138 ILE A O   1 
ATOM 925  C CB  . ILE A 1 138 ? 62.381  -73.658 -145.531 1.00 142.79 ? 138 ILE A CB  1 
ATOM 926  C CG1 . ILE A 1 138 ? 62.903  -72.649 -146.547 1.00 141.82 ? 138 ILE A CG1 1 
ATOM 927  C CG2 . ILE A 1 138 ? 61.012  -74.112 -145.966 1.00 144.17 ? 138 ILE A CG2 1 
ATOM 928  C CD1 . ILE A 1 138 ? 63.472  -73.301 -147.773 1.00 140.72 ? 138 ILE A CD1 1 
ATOM 929  N N   . LYS A 1 139 ? 62.544  -74.817 -142.387 1.00 146.50 ? 139 LYS A N   1 
ATOM 930  C CA  . LYS A 1 139 ? 61.977  -75.855 -141.533 1.00 145.56 ? 139 LYS A CA  1 
ATOM 931  C C   . LYS A 1 139 ? 61.125  -75.267 -140.419 1.00 144.49 ? 139 LYS A C   1 
ATOM 932  O O   . LYS A 1 139 ? 60.219  -75.938 -139.910 1.00 142.41 ? 139 LYS A O   1 
ATOM 933  C CB  . LYS A 1 139 ? 63.087  -76.710 -140.927 1.00 143.58 ? 139 LYS A CB  1 
ATOM 934  C CG  . LYS A 1 139 ? 64.248  -75.904 -140.384 1.00 144.02 ? 139 LYS A CG  1 
ATOM 935  C CD  . LYS A 1 139 ? 65.170  -76.761 -139.537 1.00 142.13 ? 139 LYS A CD  1 
ATOM 936  C CE  . LYS A 1 139 ? 66.475  -76.046 -139.238 1.00 142.23 ? 139 LYS A CE  1 
ATOM 937  N NZ  . LYS A 1 139 ? 66.258  -74.688 -138.670 1.00 141.31 ? 139 LYS A NZ  1 
ATOM 938  N N   . ASP A 1 140 ? 61.405  -74.026 -140.024 1.00 142.72 ? 140 ASP A N   1 
ATOM 939  C CA  . ASP A 1 140 ? 60.681  -73.415 -138.916 1.00 141.16 ? 140 ASP A CA  1 
ATOM 940  C C   . ASP A 1 140 ? 59.203  -73.240 -139.239 1.00 144.08 ? 140 ASP A C   1 
ATOM 941  O O   . ASP A 1 140 ? 58.342  -73.527 -138.400 1.00 144.61 ? 140 ASP A O   1 
ATOM 942  C CB  . ASP A 1 140 ? 61.313  -72.070 -138.575 1.00 140.32 ? 140 ASP A CB  1 
ATOM 943  C CG  . ASP A 1 140 ? 61.662  -71.272 -139.812 1.00 142.59 ? 140 ASP A CG  1 
ATOM 944  O OD1 . ASP A 1 140 ? 62.148  -71.878 -140.791 1.00 140.73 ? 140 ASP A OD1 1 
ATOM 945  O OD2 . ASP A 1 140 ? 61.446  -70.042 -139.811 1.00 145.04 ? 140 ASP A OD2 1 
ATOM 946  N N   . GLY A 1 141 ? 58.889  -72.775 -140.447 1.00 139.65 ? 141 GLY A N   1 
ATOM 947  C CA  . GLY A 1 141 ? 57.528  -72.434 -140.808 1.00 137.51 ? 141 GLY A CA  1 
ATOM 948  C C   . GLY A 1 141 ? 56.885  -73.253 -141.902 1.00 135.66 ? 141 GLY A C   1 
ATOM 949  O O   . GLY A 1 141 ? 55.754  -72.940 -142.300 1.00 135.43 ? 141 GLY A O   1 
ATOM 950  N N   . VAL A 1 142 ? 57.543  -74.292 -142.406 1.00 131.80 ? 142 VAL A N   1 
ATOM 951  C CA  . VAL A 1 142 ? 57.006  -75.106 -143.489 1.00 132.86 ? 142 VAL A CA  1 
ATOM 952  C C   . VAL A 1 142 ? 57.035  -76.564 -143.063 1.00 132.01 ? 142 VAL A C   1 
ATOM 953  O O   . VAL A 1 142 ? 58.065  -77.058 -142.590 1.00 135.14 ? 142 VAL A O   1 
ATOM 954  C CB  . VAL A 1 142 ? 57.793  -74.907 -144.795 1.00 132.98 ? 142 VAL A CB  1 
ATOM 955  C CG1 . VAL A 1 142 ? 57.496  -76.028 -145.774 1.00 132.62 ? 142 VAL A CG1 1 
ATOM 956  C CG2 . VAL A 1 142 ? 57.467  -73.559 -145.404 1.00 133.57 ? 142 VAL A CG2 1 
ATOM 957  N N   . ASN A 1 143 ? 55.911  -77.249 -143.234 1.00 130.21 ? 143 ASN A N   1 
ATOM 958  C CA  . ASN A 1 143 ? 55.774  -78.654 -142.888 1.00 130.65 ? 143 ASN A CA  1 
ATOM 959  C C   . ASN A 1 143 ? 55.718  -79.478 -144.165 1.00 132.25 ? 143 ASN A C   1 
ATOM 960  O O   . ASN A 1 143 ? 55.108  -79.065 -145.155 1.00 135.36 ? 143 ASN A O   1 
ATOM 961  C CB  . ASN A 1 143 ? 54.518  -78.892 -142.049 1.00 132.07 ? 143 ASN A CB  1 
ATOM 962  C CG  . ASN A 1 143 ? 54.372  -80.331 -141.606 1.00 133.52 ? 143 ASN A CG  1 
ATOM 963  O OD1 . ASN A 1 143 ? 55.272  -81.148 -141.797 1.00 136.39 ? 143 ASN A OD1 1 
ATOM 964  N ND2 . ASN A 1 143 ? 53.232  -80.652 -141.007 1.00 132.65 ? 143 ASN A ND2 1 
ATOM 965  N N   . ALA A 1 144 ? 56.359  -80.640 -144.138 1.00 133.40 ? 144 ALA A N   1 
ATOM 966  C CA  . ALA A 1 144 ? 56.387  -81.548 -145.271 1.00 133.50 ? 144 ALA A CA  1 
ATOM 967  C C   . ALA A 1 144 ? 55.774  -82.884 -144.877 1.00 136.23 ? 144 ALA A C   1 
ATOM 968  O O   . ALA A 1 144 ? 55.847  -83.310 -143.722 1.00 137.95 ? 144 ALA A O   1 
ATOM 969  C CB  . ALA A 1 144 ? 57.817  -81.755 -145.780 1.00 134.95 ? 144 ALA A CB  1 
ATOM 970  N N   . SER A 1 145 ? 55.161  -83.547 -145.860 1.00 142.20 ? 145 SER A N   1 
ATOM 971  C CA  . SER A 1 145 ? 54.527  -84.842 -145.615 1.00 141.71 ? 145 SER A CA  1 
ATOM 972  C C   . SER A 1 145 ? 54.595  -85.642 -146.915 1.00 141.28 ? 145 SER A C   1 
ATOM 973  O O   . SER A 1 145 ? 53.884  -85.328 -147.873 1.00 141.10 ? 145 SER A O   1 
ATOM 974  C CB  . SER A 1 145 ? 53.095  -84.675 -145.140 1.00 142.12 ? 145 SER A CB  1 
ATOM 975  O OG  . SER A 1 145 ? 52.318  -85.811 -145.473 1.00 142.67 ? 145 SER A OG  1 
ATOM 976  N N   . VAL A 1 146 ? 55.453  -86.659 -146.935 1.00 147.02 ? 146 VAL A N   1 
ATOM 977  C CA  . VAL A 1 146 ? 55.601  -87.513 -148.105 1.00 148.30 ? 146 VAL A CA  1 
ATOM 978  C C   . VAL A 1 146 ? 54.689  -88.722 -147.963 1.00 148.56 ? 146 VAL A C   1 
ATOM 979  O O   . VAL A 1 146 ? 55.115  -89.779 -147.483 1.00 149.19 ? 146 VAL A O   1 
ATOM 980  C CB  . VAL A 1 146 ? 57.064  -87.949 -148.293 1.00 149.63 ? 146 VAL A CB  1 
ATOM 981  C CG1 . VAL A 1 146 ? 57.247  -88.619 -149.647 1.00 149.07 ? 146 VAL A CG1 1 
ATOM 982  C CG2 . VAL A 1 146 ? 57.998  -86.758 -148.134 1.00 149.21 ? 146 VAL A CG2 1 
ATOM 983  N N   . THR A 1 147 ? 53.415  -88.544 -148.288 1.00 148.74 ? 147 THR A N   1 
ATOM 984  C CA  . THR A 1 147 ? 52.518  -89.714 -148.261 1.00 147.49 ? 147 THR A CA  1 
ATOM 985  C C   . THR A 1 147 ? 53.050  -90.676 -149.310 1.00 150.02 ? 147 THR A C   1 
ATOM 986  O O   . THR A 1 147 ? 53.274  -91.847 -148.963 1.00 151.25 ? 147 THR A O   1 
ATOM 987  C CB  . THR A 1 147 ? 51.106  -89.296 -148.555 1.00 147.42 ? 147 THR A CB  1 
ATOM 988  N N   . GLY A 1 148 ? 53.252  -90.194 -150.539 1.00 158.81 ? 148 GLY A N   1 
ATOM 989  C CA  . GLY A 1 148 ? 53.868  -91.024 -151.594 1.00 159.65 ? 148 GLY A CA  1 
ATOM 990  C C   . GLY A 1 148 ? 53.082  -92.276 -151.910 1.00 160.42 ? 148 GLY A C   1 
ATOM 991  O O   . GLY A 1 148 ? 52.681  -92.425 -153.080 1.00 161.23 ? 148 GLY A O   1 
ATOM 992  N N   . THR A 1 149 ? 52.908  -93.164 -150.929 1.00 164.12 ? 149 THR A N   1 
ATOM 993  C CA  . THR A 1 149 ? 52.156  -94.423 -151.128 1.00 164.21 ? 149 THR A CA  1 
ATOM 994  C C   . THR A 1 149 ? 52.696  -95.144 -152.363 1.00 165.61 ? 149 THR A C   1 
ATOM 995  O O   . THR A 1 149 ? 51.893  -95.490 -153.255 1.00 165.46 ? 149 THR A O   1 
ATOM 996  C CB  . THR A 1 149 ? 50.675  -94.141 -151.250 1.00 162.80 ? 149 THR A CB  1 
ATOM 997  N N   . GLY A 1 150 ? 54.012  -95.356 -152.415 1.00 163.85 ? 150 GLY A N   1 
ATOM 998  C CA  . GLY A 1 150 ? 54.598  -96.108 -153.538 1.00 162.50 ? 150 GLY A CA  1 
ATOM 999  C C   . GLY A 1 150 ? 54.763  -95.237 -154.761 1.00 162.53 ? 150 GLY A C   1 
ATOM 1000 O O   . GLY A 1 150 ? 54.843  -94.003 -154.604 1.00 162.23 ? 150 GLY A O   1 
ATOM 1001 N N   . ALA A 1 151 ? 54.803  -95.854 -155.940 1.00 161.43 ? 151 ALA A N   1 
ATOM 1002 C CA  . ALA A 1 151 ? 54.999  -95.104 -157.203 1.00 160.58 ? 151 ALA A CA  1 
ATOM 1003 C C   . ALA A 1 151 ? 54.265  -93.762 -157.187 1.00 162.54 ? 151 ALA A C   1 
ATOM 1004 O O   . ALA A 1 151 ? 54.846  -92.785 -157.699 1.00 160.64 ? 151 ALA A O   1 
ATOM 1005 C CB  . ALA A 1 151 ? 54.540  -95.947 -158.368 1.00 158.55 ? 151 ALA A CB  1 
ATOM 1006 N N   . SER A 1 152 ? 53.043  -93.700 -156.644 1.00 165.84 ? 152 SER A N   1 
ATOM 1007 C CA  . SER A 1 152 ? 52.310  -92.444 -156.747 1.00 163.07 ? 152 SER A CA  1 
ATOM 1008 C C   . SER A 1 152 ? 53.177  -91.265 -156.324 1.00 164.27 ? 152 SER A C   1 
ATOM 1009 O O   . SER A 1 152 ? 53.271  -90.268 -157.050 1.00 164.44 ? 152 SER A O   1 
ATOM 1010 C CB  . SER A 1 152 ? 51.037  -92.497 -155.901 1.00 160.18 ? 152 SER A CB  1 
ATOM 1011 N N   . ALA A 1 153 ? 53.814  -91.373 -155.155 1.00 163.56 ? 153 ALA A N   1 
ATOM 1012 C CA  . ALA A 1 153 ? 54.786  -90.385 -154.699 1.00 163.61 ? 153 ALA A CA  1 
ATOM 1013 C C   . ALA A 1 153 ? 54.196  -88.983 -154.608 1.00 163.70 ? 153 ALA A C   1 
ATOM 1014 O O   . ALA A 1 153 ? 54.566  -88.096 -155.383 1.00 161.81 ? 153 ALA A O   1 
ATOM 1015 C CB  . ALA A 1 153 ? 56.008  -90.386 -155.617 1.00 163.22 ? 153 ALA A CB  1 
ATOM 1016 N N   . THR A 1 154 ? 53.262  -88.778 -153.682 1.00 153.41 ? 154 THR A N   1 
ATOM 1017 C CA  . THR A 1 154 ? 52.639  -87.476 -153.461 1.00 151.85 ? 154 THR A CA  1 
ATOM 1018 C C   . THR A 1 154 ? 53.433  -86.729 -152.400 1.00 150.44 ? 154 THR A C   1 
ATOM 1019 O O   . THR A 1 154 ? 53.507  -87.173 -151.249 1.00 149.78 ? 154 THR A O   1 
ATOM 1020 C CB  . THR A 1 154 ? 51.179  -87.630 -153.037 1.00 152.62 ? 154 THR A CB  1 
ATOM 1021 O OG1 . THR A 1 154 ? 51.046  -88.782 -152.197 1.00 150.97 ? 154 THR A OG1 1 
ATOM 1022 C CG2 . THR A 1 154 ? 50.286  -87.792 -154.257 1.00 151.97 ? 154 THR A CG2 1 
ATOM 1023 N N   . MET A 1 155 ? 54.025  -85.597 -152.782 1.00 142.50 ? 155 MET A N   1 
ATOM 1024 C CA  . MET A 1 155 ? 54.807  -84.773 -151.859 1.00 141.83 ? 155 MET A CA  1 
ATOM 1025 C C   . MET A 1 155 ? 54.021  -83.502 -151.527 1.00 142.40 ? 155 MET A C   1 
ATOM 1026 O O   . MET A 1 155 ? 54.040  -82.502 -152.247 1.00 140.98 ? 155 MET A O   1 
ATOM 1027 C CB  . MET A 1 155 ? 56.171  -84.455 -152.454 1.00 140.52 ? 155 MET A CB  1 
ATOM 1028 C CG  . MET A 1 155 ? 56.972  -83.439 -151.667 1.00 140.35 ? 155 MET A CG  1 
ATOM 1029 S SD  . MET A 1 155 ? 56.945  -83.763 -149.896 1.00 145.08 ? 155 MET A SD  1 
ATOM 1030 C CE  . MET A 1 155 ? 58.017  -82.455 -149.309 1.00 142.00 ? 155 MET A CE  1 
ATOM 1031 N N   . ILE A 1 156 ? 53.317  -83.562 -150.399 1.00 134.59 ? 156 ILE A N   1 
ATOM 1032 C CA  . ILE A 1 156 ? 52.461  -82.457 -149.979 1.00 132.04 ? 156 ILE A CA  1 
ATOM 1033 C C   . ILE A 1 156 ? 53.262  -81.503 -149.103 1.00 131.35 ? 156 ILE A C   1 
ATOM 1034 O O   . ILE A 1 156 ? 53.901  -81.919 -148.130 1.00 133.47 ? 156 ILE A O   1 
ATOM 1035 C CB  . ILE A 1 156 ? 51.220  -82.978 -149.245 1.00 131.23 ? 156 ILE A CB  1 
ATOM 1036 C CG1 . ILE A 1 156 ? 50.277  -83.668 -150.231 1.00 132.44 ? 156 ILE A CG1 1 
ATOM 1037 C CG2 . ILE A 1 156 ? 50.512  -81.849 -148.524 1.00 130.90 ? 156 ILE A CG2 1 
ATOM 1038 C CD1 . ILE A 1 156 ? 49.040  -84.253 -149.586 1.00 132.31 ? 156 ILE A CD1 1 
ATOM 1039 N N   . ILE A 1 157 ? 53.223  -80.218 -149.439 1.00 122.17 ? 157 ILE A N   1 
ATOM 1040 C CA  . ILE A 1 157 ? 53.899  -79.176 -148.678 1.00 122.60 ? 157 ILE A CA  1 
ATOM 1041 C C   . ILE A 1 157 ? 52.863  -78.159 -148.221 1.00 124.53 ? 157 ILE A C   1 
ATOM 1042 O O   . ILE A 1 157 ? 51.850  -77.943 -148.896 1.00 125.54 ? 157 ILE A O   1 
ATOM 1043 C CB  . ILE A 1 157 ? 55.019  -78.502 -149.501 1.00 121.40 ? 157 ILE A CB  1 
ATOM 1044 C CG1 . ILE A 1 157 ? 56.103  -77.945 -148.580 1.00 121.40 ? 157 ILE A CG1 1 
ATOM 1045 C CG2 . ILE A 1 157 ? 54.466  -77.406 -150.397 1.00 120.60 ? 157 ILE A CG2 1 
ATOM 1046 C CD1 . ILE A 1 157 ? 57.069  -78.985 -148.083 1.00 120.95 ? 157 ILE A CD1 1 
ATOM 1047 N N   . THR A 1 158 ? 53.106  -77.555 -147.061 1.00 126.21 ? 158 THR A N   1 
ATOM 1048 C CA  . THR A 1 158 ? 52.183  -76.585 -146.496 1.00 125.72 ? 158 THR A CA  1 
ATOM 1049 C C   . THR A 1 158 ? 52.921  -75.727 -145.480 1.00 127.41 ? 158 THR A C   1 
ATOM 1050 O O   . THR A 1 158 ? 53.976  -76.114 -144.971 1.00 130.28 ? 158 THR A O   1 
ATOM 1051 C CB  . THR A 1 158 ? 50.978  -77.271 -145.836 1.00 123.08 ? 158 THR A CB  1 
ATOM 1052 O OG1 . THR A 1 158 ? 50.119  -76.287 -145.249 1.00 126.94 ? 158 THR A OG1 1 
ATOM 1053 C CG2 . THR A 1 158 ? 51.434  -78.236 -144.762 1.00 122.22 ? 158 THR A CG2 1 
ATOM 1054 N N   . LYS A 1 159 ? 52.363  -74.554 -145.198 1.00 124.29 ? 159 LYS A N   1 
ATOM 1055 C CA  . LYS A 1 159 ? 52.920  -73.696 -144.163 1.00 124.10 ? 159 LYS A CA  1 
ATOM 1056 C C   . LYS A 1 159 ? 52.725  -74.334 -142.794 1.00 127.68 ? 159 LYS A C   1 
ATOM 1057 O O   . LYS A 1 159 ? 51.668  -74.893 -142.491 1.00 127.11 ? 159 LYS A O   1 
ATOM 1058 C CB  . LYS A 1 159 ? 52.264  -72.317 -144.202 1.00 118.19 ? 159 LYS A CB  1 
ATOM 1059 N N   . ALA A 1 160 ? 53.767  -74.257 -141.957 1.00 134.52 ? 160 ALA A N   1 
ATOM 1060 C CA  . ALA A 1 160 ? 53.736  -74.903 -140.656 1.00 135.38 ? 160 ALA A CA  1 
ATOM 1061 C C   . ALA A 1 160 ? 53.462  -73.848 -139.596 1.00 134.40 ? 160 ALA A C   1 
ATOM 1062 O O   . ALA A 1 160 ? 52.448  -73.944 -138.880 1.00 135.81 ? 160 ALA A O   1 
ATOM 1063 C CB  . ALA A 1 160 ? 55.033  -75.682 -140.409 1.00 134.33 ? 160 ALA A CB  1 
ATOM 1064 N N   . GLY A 1 161 ? 54.302  -72.829 -139.451 1.00 125.10 ? 161 GLY A N   1 
ATOM 1065 C CA  . GLY A 1 161 ? 54.180  -71.942 -138.311 1.00 124.25 ? 161 GLY A CA  1 
ATOM 1066 C C   . GLY A 1 161 ? 53.772  -70.526 -138.648 1.00 126.82 ? 161 GLY A C   1 
ATOM 1067 O O   . GLY A 1 161 ? 52.749  -70.303 -139.299 1.00 130.12 ? 161 GLY A O   1 
ATOM 1068 N N   . ASP A 1 162 ? 54.573  -69.558 -138.198 1.00 121.29 ? 162 ASP A N   1 
ATOM 1069 C CA  . ASP A 1 162 ? 54.251  -68.150 -138.379 1.00 119.83 ? 162 ASP A CA  1 
ATOM 1070 C C   . ASP A 1 162 ? 54.172  -67.773 -139.853 1.00 122.48 ? 162 ASP A C   1 
ATOM 1071 O O   . ASP A 1 162 ? 53.290  -67.014 -140.267 1.00 123.84 ? 162 ASP A O   1 
ATOM 1072 C CB  . ASP A 1 162 ? 55.286  -67.284 -137.655 1.00 116.95 ? 162 ASP A CB  1 
ATOM 1073 N N   . ASN A 1 163 ? 55.098  -68.293 -140.659 1.00 121.70 ? 163 ASN A N   1 
ATOM 1074 C CA  . ASN A 1 163 ? 55.131  -67.980 -142.081 1.00 120.29 ? 163 ASN A CA  1 
ATOM 1075 C C   . ASN A 1 163 ? 53.821  -68.370 -142.750 1.00 122.93 ? 163 ASN A C   1 
ATOM 1076 O O   . ASN A 1 163 ? 53.507  -69.557 -142.869 1.00 122.20 ? 163 ASN A O   1 
ATOM 1077 C CB  . ASN A 1 163 ? 56.305  -68.686 -142.761 1.00 116.40 ? 163 ASN A CB  1 
ATOM 1078 N N   . ASP A 1 164 ? 53.051  -67.375 -143.185 1.00 122.38 ? 164 ASP A N   1 
ATOM 1079 C CA  . ASP A 1 164 ? 51.761  -67.606 -143.817 1.00 121.84 ? 164 ASP A CA  1 
ATOM 1080 C C   . ASP A 1 164 ? 51.844  -67.653 -145.334 1.00 122.00 ? 164 ASP A C   1 
ATOM 1081 O O   . ASP A 1 164 ? 50.812  -67.814 -145.993 1.00 124.54 ? 164 ASP A O   1 
ATOM 1082 C CB  . ASP A 1 164 ? 50.760  -66.528 -143.388 1.00 116.33 ? 164 ASP A CB  1 
ATOM 1083 N N   . PHE A 1 165 ? 53.037  -67.520 -145.905 1.00 110.24 ? 165 PHE A N   1 
ATOM 1084 C CA  . PHE A 1 165 ? 53.237  -67.574 -147.345 1.00 111.01 ? 165 PHE A CA  1 
ATOM 1085 C C   . PHE A 1 165 ? 54.064  -68.806 -147.669 1.00 113.24 ? 165 PHE A C   1 
ATOM 1086 O O   . PHE A 1 165 ? 55.093  -69.049 -147.033 1.00 115.20 ? 165 PHE A O   1 
ATOM 1087 C CB  . PHE A 1 165 ? 53.929  -66.301 -147.846 1.00 111.57 ? 165 PHE A CB  1 
ATOM 1088 C CG  . PHE A 1 165 ? 54.203  -66.284 -149.329 1.00 111.48 ? 165 PHE A CG  1 
ATOM 1089 C CD1 . PHE A 1 165 ? 55.236  -67.022 -149.882 1.00 116.66 ? 165 PHE A CD1 1 
ATOM 1090 C CD2 . PHE A 1 165 ? 53.457  -65.481 -150.162 1.00 108.82 ? 165 PHE A CD2 1 
ATOM 1091 C CE1 . PHE A 1 165 ? 55.485  -66.985 -151.238 1.00 114.62 ? 165 PHE A CE1 1 
ATOM 1092 C CE2 . PHE A 1 165 ? 53.710  -65.434 -151.513 1.00 113.35 ? 165 PHE A CE2 1 
ATOM 1093 C CZ  . PHE A 1 165 ? 54.719  -66.190 -152.053 1.00 112.42 ? 165 PHE A CZ  1 
ATOM 1094 N N   . VAL A 1 166 ? 53.611  -69.579 -148.649 1.00 112.01 ? 166 VAL A N   1 
ATOM 1095 C CA  . VAL A 1 166 ? 54.330  -70.755 -149.124 1.00 107.44 ? 166 VAL A CA  1 
ATOM 1096 C C   . VAL A 1 166 ? 54.101  -70.871 -150.621 1.00 109.03 ? 166 VAL A C   1 
ATOM 1097 O O   . VAL A 1 166 ? 52.958  -70.799 -151.084 1.00 113.01 ? 166 VAL A O   1 
ATOM 1098 C CB  . VAL A 1 166 ? 53.872  -72.037 -148.403 1.00 109.51 ? 166 VAL A CB  1 
ATOM 1099 C CG1 . VAL A 1 166 ? 54.147  -73.255 -149.256 1.00 116.03 ? 166 VAL A CG1 1 
ATOM 1100 C CG2 . VAL A 1 166 ? 54.565  -72.165 -147.068 1.00 111.17 ? 166 VAL A CG2 1 
ATOM 1101 N N   . LYS A 1 167 ? 55.181  -71.048 -151.381 1.00 113.14 ? 167 LYS A N   1 
ATOM 1102 C CA  . LYS A 1 167 ? 55.076  -71.139 -152.836 1.00 115.54 ? 167 LYS A CA  1 
ATOM 1103 C C   . LYS A 1 167 ? 56.268  -71.957 -153.325 1.00 118.64 ? 167 LYS A C   1 
ATOM 1104 O O   . LYS A 1 167 ? 57.417  -71.551 -153.140 1.00 122.00 ? 167 LYS A O   1 
ATOM 1105 C CB  . LYS A 1 167 ? 55.044  -69.754 -153.466 1.00 116.53 ? 167 LYS A CB  1 
ATOM 1106 C CG  . LYS A 1 167 ? 54.972  -69.758 -154.977 1.00 116.48 ? 167 LYS A CG  1 
ATOM 1107 C CD  . LYS A 1 167 ? 54.121  -68.604 -155.483 1.00 119.37 ? 167 LYS A CD  1 
ATOM 1108 C CE  . LYS A 1 167 ? 52.673  -69.029 -155.689 1.00 118.96 ? 167 LYS A CE  1 
ATOM 1109 N NZ  . LYS A 1 167 ? 51.972  -68.185 -156.696 1.00 115.88 ? 167 LYS A NZ  1 
ATOM 1110 N N   . VAL A 1 168 ? 55.987  -73.101 -153.945 1.00 119.61 ? 168 VAL A N   1 
ATOM 1111 C CA  . VAL A 1 168 ? 57.038  -74.042 -154.314 1.00 120.83 ? 168 VAL A CA  1 
ATOM 1112 C C   . VAL A 1 168 ? 57.059  -74.257 -155.821 1.00 122.35 ? 168 VAL A C   1 
ATOM 1113 O O   . VAL A 1 168 ? 57.351  -75.361 -156.294 1.00 123.64 ? 168 VAL A O   1 
ATOM 1114 C CB  . VAL A 1 168 ? 56.863  -75.377 -153.574 1.00 120.83 ? 168 VAL A CB  1 
ATOM 1115 C CG1 . VAL A 1 168 ? 57.017  -75.173 -152.081 1.00 119.94 ? 168 VAL A CG1 1 
ATOM 1116 C CG2 . VAL A 1 168 ? 55.518  -75.980 -153.889 1.00 121.64 ? 168 VAL A CG2 1 
ATOM 1117 N N   . THR A 1 169 ? 56.744  -73.213 -156.583 1.00 134.09 ? 169 THR A N   1 
ATOM 1118 C CA  . THR A 1 169 ? 56.784  -73.314 -158.036 1.00 135.40 ? 169 THR A CA  1 
ATOM 1119 C C   . THR A 1 169 ? 58.164  -73.746 -158.508 1.00 136.97 ? 169 THR A C   1 
ATOM 1120 O O   . THR A 1 169 ? 59.183  -73.203 -158.072 1.00 136.85 ? 169 THR A O   1 
ATOM 1121 C CB  . THR A 1 169 ? 56.410  -71.976 -158.671 1.00 136.80 ? 169 THR A CB  1 
ATOM 1122 O OG1 . THR A 1 169 ? 57.469  -71.035 -158.456 1.00 140.42 ? 169 THR A OG1 1 
ATOM 1123 C CG2 . THR A 1 169 ? 55.121  -71.445 -158.080 1.00 136.02 ? 169 THR A CG2 1 
ATOM 1124 N N   . SER A 1 170 ? 58.188  -74.725 -159.407 1.00 148.94 ? 170 SER A N   1 
ATOM 1125 C CA  . SER A 1 170 ? 59.428  -75.311 -159.897 1.00 149.15 ? 170 SER A CA  1 
ATOM 1126 C C   . SER A 1 170 ? 59.406  -75.318 -161.415 1.00 150.33 ? 170 SER A C   1 
ATOM 1127 O O   . SER A 1 170 ? 58.426  -75.760 -162.019 1.00 151.28 ? 170 SER A O   1 
ATOM 1128 C CB  . SER A 1 170 ? 59.613  -76.733 -159.368 1.00 149.37 ? 170 SER A CB  1 
ATOM 1129 O OG  . SER A 1 170 ? 60.607  -77.414 -160.112 1.00 150.34 ? 170 SER A OG  1 
ATOM 1130 N N   . ILE A 1 171 ? 60.487  -74.844 -162.027 1.00 153.08 ? 171 ILE A N   1 
ATOM 1131 C CA  . ILE A 1 171 ? 60.623  -74.920 -163.471 1.00 155.02 ? 171 ILE A CA  1 
ATOM 1132 C C   . ILE A 1 171 ? 60.945  -76.354 -163.884 1.00 158.24 ? 171 ILE A C   1 
ATOM 1133 O O   . ILE A 1 171 ? 61.078  -77.255 -163.050 1.00 158.14 ? 171 ILE A O   1 
ATOM 1134 C CB  . ILE A 1 171 ? 61.693  -73.945 -163.954 1.00 150.32 ? 171 ILE A CB  1 
ATOM 1135 N N   . THR A 1 172 ? 61.051  -76.568 -165.201 1.00 155.14 ? 172 THR A N   1 
ATOM 1136 C CA  . THR A 1 172 ? 61.477  -77.820 -165.824 1.00 152.49 ? 172 THR A CA  1 
ATOM 1137 C C   . THR A 1 172 ? 60.444  -78.927 -165.655 1.00 152.12 ? 172 THR A C   1 
ATOM 1138 O O   . THR A 1 172 ? 59.751  -78.990 -164.633 1.00 152.64 ? 172 THR A O   1 
ATOM 1139 C CB  . THR A 1 172 ? 62.828  -78.276 -165.266 1.00 150.12 ? 172 THR A CB  1 
ATOM 1140 N N   . PRO A 1 173 ? 60.311  -79.814 -166.642 1.00 151.39 ? 173 PRO A N   1 
ATOM 1141 C CA  . PRO A 1 173 ? 59.378  -80.945 -166.499 1.00 152.35 ? 173 PRO A CA  1 
ATOM 1142 C C   . PRO A 1 173 ? 59.774  -81.932 -165.415 1.00 151.67 ? 173 PRO A C   1 
ATOM 1143 O O   . PRO A 1 173 ? 59.026  -82.883 -165.154 1.00 149.82 ? 173 PRO A O   1 
ATOM 1144 C CB  . PRO A 1 173 ? 59.412  -81.607 -167.884 1.00 151.31 ? 173 PRO A CB  1 
ATOM 1145 C CG  . PRO A 1 173 ? 60.612  -81.038 -168.576 1.00 150.05 ? 173 PRO A CG  1 
ATOM 1146 C CD  . PRO A 1 173 ? 60.819  -79.680 -168.013 1.00 150.89 ? 173 PRO A CD  1 
ATOM 1147 N N   . THR A 1 174 ? 60.933  -81.745 -164.787 1.00 153.99 ? 174 THR A N   1 
ATOM 1148 C CA  . THR A 1 174 ? 61.446  -82.672 -163.786 1.00 153.59 ? 174 THR A CA  1 
ATOM 1149 C C   . THR A 1 174 ? 60.478  -82.862 -162.625 1.00 155.18 ? 174 THR A C   1 
ATOM 1150 O O   . THR A 1 174 ? 60.190  -83.998 -162.235 1.00 153.93 ? 174 THR A O   1 
ATOM 1151 C CB  . THR A 1 174 ? 62.793  -82.179 -163.259 1.00 152.41 ? 174 THR A CB  1 
ATOM 1152 O OG1 . THR A 1 174 ? 62.622  -80.902 -162.633 1.00 150.98 ? 174 THR A OG1 1 
ATOM 1153 C CG2 . THR A 1 174 ? 63.786  -82.047 -164.398 1.00 151.67 ? 174 THR A CG2 1 
ATOM 1154 N N   . THR A 1 175 ? 59.967  -81.767 -162.073 1.00 157.38 ? 175 THR A N   1 
ATOM 1155 C CA  . THR A 1 175 ? 59.076  -81.820 -160.923 1.00 155.63 ? 175 THR A CA  1 
ATOM 1156 C C   . THR A 1 175 ? 57.641  -81.556 -161.356 1.00 157.29 ? 175 THR A C   1 
ATOM 1157 O O   . THR A 1 175 ? 57.352  -80.552 -162.013 1.00 156.46 ? 175 THR A O   1 
ATOM 1158 C CB  . THR A 1 175 ? 59.499  -80.806 -159.861 1.00 151.92 ? 175 THR A CB  1 
ATOM 1159 N N   . SER A 1 176 ? 56.745  -82.466 -160.984 1.00 155.19 ? 176 SER A N   1 
ATOM 1160 C CA  . SER A 1 176 ? 55.323  -82.348 -161.312 1.00 153.66 ? 176 SER A CA  1 
ATOM 1161 C C   . SER A 1 176 ? 54.557  -81.725 -160.147 1.00 154.84 ? 176 SER A C   1 
ATOM 1162 O O   . SER A 1 176 ? 53.821  -82.386 -159.416 1.00 155.26 ? 176 SER A O   1 
ATOM 1163 C CB  . SER A 1 176 ? 54.752  -83.711 -161.688 1.00 151.13 ? 176 SER A CB  1 
ATOM 1164 N N   . ILE A 1 177 ? 54.747  -80.416 -159.988 1.00 147.42 ? 177 ILE A N   1 
ATOM 1165 C CA  . ILE A 1 177 ? 54.145  -79.693 -158.875 1.00 145.37 ? 177 ILE A CA  1 
ATOM 1166 C C   . ILE A 1 177 ? 52.655  -79.505 -159.122 1.00 145.78 ? 177 ILE A C   1 
ATOM 1167 O O   . ILE A 1 177 ? 52.182  -79.572 -160.265 1.00 147.58 ? 177 ILE A O   1 
ATOM 1168 C CB  . ILE A 1 177 ? 54.842  -78.341 -158.679 1.00 142.78 ? 177 ILE A CB  1 
ATOM 1169 C CG1 . ILE A 1 177 ? 54.456  -77.391 -159.812 1.00 142.31 ? 177 ILE A CG1 1 
ATOM 1170 C CG2 . ILE A 1 177 ? 56.344  -78.527 -158.616 1.00 141.15 ? 177 ILE A CG2 1 
ATOM 1171 C CD1 . ILE A 1 177 ? 55.161  -76.065 -159.767 1.00 142.63 ? 177 ILE A CD1 1 
ATOM 1172 N N   . ALA A 1 178 ? 51.911  -79.271 -158.049 1.00 132.26 ? 178 ALA A N   1 
ATOM 1173 C CA  . ALA A 1 178 ? 50.499  -78.921 -158.089 1.00 130.07 ? 178 ALA A CA  1 
ATOM 1174 C C   . ALA A 1 178 ? 50.250  -77.765 -157.127 1.00 129.99 ? 178 ALA A C   1 
ATOM 1175 O O   . ALA A 1 178 ? 51.125  -77.374 -156.353 1.00 131.25 ? 178 ALA A O   1 
ATOM 1176 C CB  . ALA A 1 178 ? 49.624  -80.128 -157.743 1.00 128.57 ? 178 ALA A CB  1 
ATOM 1177 N N   . ALA A 1 179 ? 49.042  -77.210 -157.180 1.00 115.50 ? 179 ALA A N   1 
ATOM 1178 C CA  . ALA A 1 179 ? 48.679  -76.098 -156.306 1.00 113.47 ? 179 ALA A CA  1 
ATOM 1179 C C   . ALA A 1 179 ? 47.184  -76.142 -156.047 1.00 111.86 ? 179 ALA A C   1 
ATOM 1180 O O   . ALA A 1 179 ? 46.390  -75.914 -156.962 1.00 113.51 ? 179 ALA A O   1 
ATOM 1181 C CB  . ALA A 1 179 ? 49.078  -74.759 -156.924 1.00 112.41 ? 179 ALA A CB  1 
ATOM 1182 N N   . THR A 1 180 ? 46.804  -76.437 -154.809 1.00 106.63 ? 180 THR A N   1 
ATOM 1183 C CA  . THR A 1 180 ? 45.406  -76.486 -154.418 1.00 107.78 ? 180 THR A CA  1 
ATOM 1184 C C   . THR A 1 180 ? 45.223  -75.775 -153.086 1.00 113.15 ? 180 THR A C   1 
ATOM 1185 O O   . THR A 1 180 ? 46.120  -75.749 -152.241 1.00 117.71 ? 180 THR A O   1 
ATOM 1186 C CB  . THR A 1 180 ? 44.894  -77.930 -154.304 1.00 107.64 ? 180 THR A CB  1 
ATOM 1187 O OG1 . THR A 1 180 ? 45.701  -78.654 -153.368 1.00 108.14 ? 180 THR A OG1 1 
ATOM 1188 C CG2 . THR A 1 180 ? 44.938  -78.628 -155.653 1.00 108.79 ? 180 THR A CG2 1 
ATOM 1189 N N   . THR A 1 181 ? 44.041  -75.194 -152.907 1.00 109.39 ? 181 THR A N   1 
ATOM 1190 C CA  . THR A 1 181 ? 43.693  -74.562 -151.645 1.00 104.70 ? 181 THR A CA  1 
ATOM 1191 C C   . THR A 1 181 ? 43.462  -75.622 -150.578 1.00 107.52 ? 181 THR A C   1 
ATOM 1192 O O   . THR A 1 181 ? 42.854  -76.663 -150.841 1.00 106.70 ? 181 THR A O   1 
ATOM 1193 C CB  . THR A 1 181 ? 42.443  -73.705 -151.806 1.00 107.96 ? 181 THR A CB  1 
ATOM 1194 O OG1 . THR A 1 181 ? 41.281  -74.518 -151.595 1.00 109.24 ? 181 THR A OG1 1 
ATOM 1195 C CG2 . THR A 1 181 ? 42.389  -73.114 -153.201 1.00 110.26 ? 181 THR A CG2 1 
ATOM 1196 N N   . ALA A 1 182 ? 43.946  -75.352 -149.368 1.00 109.71 ? 182 ALA A N   1 
ATOM 1197 C CA  . ALA A 1 182 ? 43.882  -76.312 -148.274 1.00 112.99 ? 182 ALA A CA  1 
ATOM 1198 C C   . ALA A 1 182 ? 43.229  -75.723 -147.031 1.00 111.20 ? 182 ALA A C   1 
ATOM 1199 O O   . ALA A 1 182 ? 43.632  -76.029 -145.910 1.00 111.92 ? 182 ALA A O   1 
ATOM 1200 C CB  . ALA A 1 182 ? 45.274  -76.836 -147.933 1.00 115.03 ? 182 ALA A CB  1 
ATOM 1201 N N   . ASP A 1 183 ? 42.230  -74.871 -147.212 1.00 117.52 ? 183 ASP A N   1 
ATOM 1202 C CA  . ASP A 1 183 ? 41.512  -74.290 -146.091 1.00 118.15 ? 183 ASP A CA  1 
ATOM 1203 C C   . ASP A 1 183 ? 40.017  -74.340 -146.355 1.00 119.79 ? 183 ASP A C   1 
ATOM 1204 O O   . ASP A 1 183 ? 39.566  -74.223 -147.497 1.00 121.20 ? 183 ASP A O   1 
ATOM 1205 C CB  . ASP A 1 183 ? 41.953  -72.846 -145.830 1.00 121.09 ? 183 ASP A CB  1 
ATOM 1206 C CG  . ASP A 1 183 ? 42.099  -72.041 -147.105 1.00 125.36 ? 183 ASP A CG  1 
ATOM 1207 O OD1 . ASP A 1 183 ? 41.537  -72.448 -148.141 1.00 127.31 ? 183 ASP A OD1 1 
ATOM 1208 O OD2 . ASP A 1 183 ? 42.787  -70.999 -147.072 1.00 125.10 ? 183 ASP A OD2 1 
ATOM 1209 N N   . THR A 1 184 ? 39.251  -74.521 -145.285 1.00 107.74 ? 184 THR A N   1 
ATOM 1210 C CA  . THR A 1 184 ? 37.806  -74.442 -145.386 1.00 103.60 ? 184 THR A CA  1 
ATOM 1211 C C   . THR A 1 184 ? 37.380  -72.980 -145.433 1.00 104.04 ? 184 THR A C   1 
ATOM 1212 O O   . THR A 1 184 ? 38.203  -72.063 -145.430 1.00 106.22 ? 184 THR A O   1 
ATOM 1213 C CB  . THR A 1 184 ? 37.145  -75.160 -144.215 1.00 102.36 ? 184 THR A CB  1 
ATOM 1214 O OG1 . THR A 1 184 ? 37.750  -74.728 -142.991 1.00 100.83 ? 184 THR A OG1 1 
ATOM 1215 C CG2 . THR A 1 184 ? 37.312  -76.660 -144.354 1.00 104.01 ? 184 THR A CG2 1 
ATOM 1216 N N   . ALA A 1 185 ? 36.067  -72.754 -145.477 1.00 96.56  ? 185 ALA A N   1 
ATOM 1217 C CA  . ALA A 1 185 ? 35.569  -71.386 -145.465 1.00 96.14  ? 185 ALA A CA  1 
ATOM 1218 C C   . ALA A 1 185 ? 35.934  -70.682 -144.166 1.00 96.94  ? 185 ALA A C   1 
ATOM 1219 O O   . ALA A 1 185 ? 36.263  -69.492 -144.170 1.00 96.36  ? 185 ALA A O   1 
ATOM 1220 C CB  . ALA A 1 185 ? 34.058  -71.373 -145.677 1.00 95.89  ? 185 ALA A CB  1 
ATOM 1221 N N   . SER A 1 186 ? 35.886  -71.402 -143.045 1.00 98.80  ? 186 SER A N   1 
ATOM 1222 C CA  . SER A 1 186 ? 36.179  -70.784 -141.756 1.00 99.07  ? 186 SER A CA  1 
ATOM 1223 C C   . SER A 1 186 ? 37.626  -70.326 -141.675 1.00 97.54  ? 186 SER A C   1 
ATOM 1224 O O   . SER A 1 186 ? 37.906  -69.203 -141.244 1.00 97.25  ? 186 SER A O   1 
ATOM 1225 C CB  . SER A 1 186 ? 35.859  -71.754 -140.621 1.00 98.38  ? 186 SER A CB  1 
ATOM 1226 O OG  . SER A 1 186 ? 34.607  -72.381 -140.829 1.00 101.66 ? 186 SER A OG  1 
ATOM 1227 N N   . ALA A 1 187 ? 38.561  -71.186 -142.074 1.00 103.83 ? 187 ALA A N   1 
ATOM 1228 C CA  . ALA A 1 187 ? 39.968  -70.811 -142.010 1.00 106.42 ? 187 ALA A CA  1 
ATOM 1229 C C   . ALA A 1 187 ? 40.256  -69.623 -142.912 1.00 102.98 ? 187 ALA A C   1 
ATOM 1230 O O   . ALA A 1 187 ? 40.932  -68.672 -142.503 1.00 102.08 ? 187 ALA A O   1 
ATOM 1231 C CB  . ALA A 1 187 ? 40.847  -72.001 -142.389 1.00 104.82 ? 187 ALA A CB  1 
ATOM 1232 N N   . ALA A 1 188 ? 39.735  -69.653 -144.140 1.00 92.06  ? 188 ALA A N   1 
ATOM 1233 C CA  . ALA A 1 188 ? 39.972  -68.555 -145.068 1.00 94.19  ? 188 ALA A CA  1 
ATOM 1234 C C   . ALA A 1 188 ? 39.371  -67.256 -144.553 1.00 95.39  ? 188 ALA A C   1 
ATOM 1235 O O   . ALA A 1 188 ? 40.015  -66.203 -144.605 1.00 98.69  ? 188 ALA A O   1 
ATOM 1236 C CB  . ALA A 1 188 ? 39.403  -68.899 -146.441 1.00 95.03  ? 188 ALA A CB  1 
ATOM 1237 N N   . LEU A 1 189 ? 38.143  -67.312 -144.041 1.00 87.82  ? 189 LEU A N   1 
ATOM 1238 C CA  . LEU A 1 189 ? 37.501  -66.103 -143.541 1.00 89.40  ? 189 LEU A CA  1 
ATOM 1239 C C   . LEU A 1 189 ? 38.221  -65.551 -142.321 1.00 89.29  ? 189 LEU A C   1 
ATOM 1240 O O   . LEU A 1 189 ? 38.387  -64.335 -142.195 1.00 88.86  ? 189 LEU A O   1 
ATOM 1241 C CB  . LEU A 1 189 ? 36.036  -66.376 -143.220 1.00 89.97  ? 189 LEU A CB  1 
ATOM 1242 C CG  . LEU A 1 189 ? 35.206  -65.105 -143.075 1.00 85.93  ? 189 LEU A CG  1 
ATOM 1243 C CD1 . LEU A 1 189 ? 35.181  -64.349 -144.385 1.00 85.57  ? 189 LEU A CD1 1 
ATOM 1244 C CD2 . LEU A 1 189 ? 33.801  -65.441 -142.620 1.00 87.20  ? 189 LEU A CD2 1 
ATOM 1245 N N   . ALA A 1 190 ? 38.642  -66.420 -141.402 1.00 92.06  ? 190 ALA A N   1 
ATOM 1246 C CA  . ALA A 1 190 ? 39.362  -65.947 -140.228 1.00 90.91  ? 190 ALA A CA  1 
ATOM 1247 C C   . ALA A 1 190 ? 40.694  -65.326 -140.619 1.00 92.04  ? 190 ALA A C   1 
ATOM 1248 O O   . ALA A 1 190 ? 41.071  -64.270 -140.098 1.00 94.38  ? 190 ALA A O   1 
ATOM 1249 C CB  . ALA A 1 190 ? 39.571  -67.093 -139.242 1.00 92.57  ? 190 ALA A CB  1 
ATOM 1250 N N   . SER A 1 191 ? 41.415  -65.958 -141.546 1.00 87.14  ? 191 SER A N   1 
ATOM 1251 C CA  . SER A 1 191 ? 42.680  -65.396 -141.995 1.00 87.11  ? 191 SER A CA  1 
ATOM 1252 C C   . SER A 1 191 ? 42.473  -64.049 -142.672 1.00 91.15  ? 191 SER A C   1 
ATOM 1253 O O   . SER A 1 191 ? 43.256  -63.116 -142.466 1.00 90.00  ? 191 SER A O   1 
ATOM 1254 C CB  . SER A 1 191 ? 43.376  -66.368 -142.943 1.00 87.14  ? 191 SER A CB  1 
ATOM 1255 O OG  . SER A 1 191 ? 44.249  -65.670 -143.806 1.00 92.34  ? 191 SER A OG  1 
ATOM 1256 N N   . ILE A 1 192 ? 41.425  -63.932 -143.487 1.00 90.67  ? 192 ILE A N   1 
ATOM 1257 C CA  . ILE A 1 192 ? 41.150  -62.672 -144.167 1.00 85.06  ? 192 ILE A CA  1 
ATOM 1258 C C   . ILE A 1 192 ? 40.782  -61.588 -143.164 1.00 85.72  ? 192 ILE A C   1 
ATOM 1259 O O   . ILE A 1 192 ? 41.282  -60.460 -143.239 1.00 95.42  ? 192 ILE A O   1 
ATOM 1260 C CB  . ILE A 1 192 ? 40.044  -62.875 -145.214 1.00 83.02  ? 192 ILE A CB  1 
ATOM 1261 C CG1 . ILE A 1 192 ? 40.610  -63.579 -146.443 1.00 85.91  ? 192 ILE A CG1 1 
ATOM 1262 C CG2 . ILE A 1 192 ? 39.429  -61.552 -145.596 1.00 86.07  ? 192 ILE A CG2 1 
ATOM 1263 C CD1 . ILE A 1 192 ? 41.534  -62.717 -147.256 1.00 89.11  ? 192 ILE A CD1 1 
ATOM 1264 N N   . GLU A 1 193 ? 39.915  -61.911 -142.206 1.00 85.67  ? 193 GLU A N   1 
ATOM 1265 C CA  . GLU A 1 193 ? 39.487  -60.922 -141.226 1.00 90.25  ? 193 GLU A CA  1 
ATOM 1266 C C   . GLU A 1 193 ? 40.617  -60.525 -140.290 1.00 92.60  ? 193 GLU A C   1 
ATOM 1267 O O   . GLU A 1 193 ? 40.607  -59.416 -139.747 1.00 97.29  ? 193 GLU A O   1 
ATOM 1268 C CB  . GLU A 1 193 ? 38.305  -61.456 -140.424 1.00 95.09  ? 193 GLU A CB  1 
ATOM 1269 C CG  . GLU A 1 193 ? 36.979  -61.348 -141.139 1.00 97.25  ? 193 GLU A CG  1 
ATOM 1270 C CD  . GLU A 1 193 ? 35.827  -61.801 -140.275 1.00 99.57  ? 193 GLU A CD  1 
ATOM 1271 O OE1 . GLU A 1 193 ? 36.082  -62.316 -139.167 1.00 103.50 ? 193 GLU A OE1 1 
ATOM 1272 O OE2 . GLU A 1 193 ? 34.666  -61.637 -140.701 1.00 95.92  ? 193 GLU A OE2 1 
ATOM 1273 N N   . THR A 1 194 ? 41.590  -61.410 -140.078 1.00 84.53  ? 194 THR A N   1 
ATOM 1274 C CA  . THR A 1 194 ? 42.736  -61.042 -139.262 1.00 82.98  ? 194 THR A CA  1 
ATOM 1275 C C   . THR A 1 194 ? 43.533  -59.905 -139.882 1.00 81.72  ? 194 THR A C   1 
ATOM 1276 O O   . THR A 1 194 ? 44.236  -59.192 -139.162 1.00 85.41  ? 194 THR A O   1 
ATOM 1277 C CB  . THR A 1 194 ? 43.638  -62.256 -139.046 1.00 87.98  ? 194 THR A CB  1 
ATOM 1278 O OG1 . THR A 1 194 ? 42.826  -63.413 -138.812 1.00 90.68  ? 194 THR A OG1 1 
ATOM 1279 C CG2 . THR A 1 194 ? 44.548  -62.039 -137.853 1.00 88.83  ? 194 THR A CG2 1 
ATOM 1280 N N   . TYR A 1 195 ? 43.430  -59.710 -141.193 1.00 82.54  ? 195 TYR A N   1 
ATOM 1281 C CA  . TYR A 1 195 ? 44.173  -58.643 -141.851 1.00 84.73  ? 195 TYR A CA  1 
ATOM 1282 C C   . TYR A 1 195 ? 43.385  -57.336 -141.856 1.00 89.46  ? 195 TYR A C   1 
ATOM 1283 O O   . TYR A 1 195 ? 43.845  -56.326 -141.318 1.00 92.78  ? 195 TYR A O   1 
ATOM 1284 C CB  . TYR A 1 195 ? 44.530  -59.053 -143.281 1.00 88.62  ? 195 TYR A CB  1 
ATOM 1285 C CG  . TYR A 1 195 ? 45.620  -58.209 -143.887 1.00 91.30  ? 195 TYR A CG  1 
ATOM 1286 C CD1 . TYR A 1 195 ? 46.947  -58.416 -143.552 1.00 91.38  ? 195 TYR A CD1 1 
ATOM 1287 C CD2 . TYR A 1 195 ? 45.322  -57.199 -144.785 1.00 89.54  ? 195 TYR A CD2 1 
ATOM 1288 C CE1 . TYR A 1 195 ? 47.946  -57.649 -144.101 1.00 95.24  ? 195 TYR A CE1 1 
ATOM 1289 C CE2 . TYR A 1 195 ? 46.314  -56.425 -145.338 1.00 89.19  ? 195 TYR A CE2 1 
ATOM 1290 C CZ  . TYR A 1 195 ? 47.625  -56.654 -144.993 1.00 95.20  ? 195 TYR A CZ  1 
ATOM 1291 O OH  . TYR A 1 195 ? 48.622  -55.884 -145.542 1.00 97.91  ? 195 TYR A OH  1 
ATOM 1292 N N   . SER A 1 196 ? 42.201  -57.345 -142.460 1.00 89.23  ? 196 SER A N   1 
ATOM 1293 C CA  . SER A 1 196 ? 41.367  -56.156 -142.528 1.00 86.10  ? 196 SER A CA  1 
ATOM 1294 C C   . SER A 1 196 ? 39.908  -56.575 -142.565 1.00 87.02  ? 196 SER A C   1 
ATOM 1295 O O   . SER A 1 196 ? 39.580  -57.700 -142.946 1.00 91.53  ? 196 SER A O   1 
ATOM 1296 C CB  . SER A 1 196 ? 41.696  -55.301 -143.755 1.00 85.91  ? 196 SER A CB  1 
ATOM 1297 O OG  . SER A 1 196 ? 40.570  -54.538 -144.149 1.00 80.98  ? 196 SER A OG  1 
ATOM 1298 N N   . THR A 1 197 ? 39.032  -55.651 -142.176 1.00 93.31  ? 197 THR A N   1 
ATOM 1299 C CA  . THR A 1 197 ? 37.604  -55.933 -142.089 1.00 91.79  ? 197 THR A CA  1 
ATOM 1300 C C   . THR A 1 197 ? 36.788  -54.763 -142.640 1.00 92.62  ? 197 THR A C   1 
ATOM 1301 O O   . THR A 1 197 ? 35.594  -54.643 -142.356 1.00 92.71  ? 197 THR A O   1 
ATOM 1302 C CB  . THR A 1 197 ? 37.226  -56.253 -140.637 1.00 89.84  ? 197 THR A CB  1 
ATOM 1303 O OG1 . THR A 1 197 ? 38.156  -57.210 -140.120 1.00 90.63  ? 197 THR A OG1 1 
ATOM 1304 C CG2 . THR A 1 197 ? 35.847  -56.892 -140.547 1.00 90.55  ? 197 THR A CG2 1 
ATOM 1305 N N   . ASP A 1 198 ? 37.414  -53.897 -143.433 1.00 95.80  ? 198 ASP A N   1 
ATOM 1306 C CA  . ASP A 1 198 ? 36.752  -52.734 -144.007 1.00 96.74  ? 198 ASP A CA  1 
ATOM 1307 C C   . ASP A 1 198 ? 36.139  -53.007 -145.378 1.00 96.45  ? 198 ASP A C   1 
ATOM 1308 O O   . ASP A 1 198 ? 35.922  -52.067 -146.149 1.00 100.03 ? 198 ASP A O   1 
ATOM 1309 C CB  . ASP A 1 198 ? 37.730  -51.554 -144.050 1.00 96.58  ? 198 ASP A CB  1 
ATOM 1310 C CG  . ASP A 1 198 ? 38.821  -51.706 -145.109 1.00 104.00 ? 198 ASP A CG  1 
ATOM 1311 O OD1 . ASP A 1 198 ? 38.704  -52.531 -146.036 1.00 102.98 ? 198 ASP A OD1 1 
ATOM 1312 O OD2 . ASP A 1 198 ? 39.826  -50.973 -145.003 1.00 107.35 ? 198 ASP A OD2 1 
ATOM 1313 N N   . TRP A 1 199 ? 35.857  -54.264 -145.693 1.00 70.52  ? 199 TRP A N   1 
ATOM 1314 C CA  . TRP A 1 199 ? 35.243  -54.660 -146.949 1.00 68.80  ? 199 TRP A CA  1 
ATOM 1315 C C   . TRP A 1 199 ? 33.818  -55.127 -146.693 1.00 73.25  ? 199 TRP A C   1 
ATOM 1316 O O   . TRP A 1 199 ? 33.507  -55.655 -145.623 1.00 80.71  ? 199 TRP A O   1 
ATOM 1317 C CB  . TRP A 1 199 ? 36.043  -55.776 -147.613 1.00 68.00  ? 199 TRP A CB  1 
ATOM 1318 C CG  . TRP A 1 199 ? 36.389  -56.854 -146.655 1.00 69.68  ? 199 TRP A CG  1 
ATOM 1319 C CD1 . TRP A 1 199 ? 37.467  -56.895 -145.829 1.00 74.64  ? 199 TRP A CD1 1 
ATOM 1320 C CD2 . TRP A 1 199 ? 35.639  -58.041 -146.394 1.00 67.20  ? 199 TRP A CD2 1 
ATOM 1321 N NE1 . TRP A 1 199 ? 37.443  -58.039 -145.078 1.00 72.94  ? 199 TRP A NE1 1 
ATOM 1322 C CE2 . TRP A 1 199 ? 36.329  -58.761 -145.407 1.00 67.93  ? 199 TRP A CE2 1 
ATOM 1323 C CE3 . TRP A 1 199 ? 34.453  -58.570 -146.905 1.00 67.89  ? 199 TRP A CE3 1 
ATOM 1324 C CZ2 . TRP A 1 199 ? 35.876  -59.978 -144.921 1.00 70.39  ? 199 TRP A CZ2 1 
ATOM 1325 C CZ3 . TRP A 1 199 ? 34.008  -59.778 -146.424 1.00 66.27  ? 199 TRP A CZ3 1 
ATOM 1326 C CH2 . TRP A 1 199 ? 34.715  -60.468 -145.441 1.00 72.05  ? 199 TRP A CH2 1 
ATOM 1327 N N   . TYR A 1 200 ? 32.949  -54.930 -147.681 1.00 63.27  ? 200 TYR A N   1 
ATOM 1328 C CA  . TYR A 1 200 ? 31.540  -55.269 -147.534 1.00 58.19  ? 200 TYR A CA  1 
ATOM 1329 C C   . TYR A 1 200 ? 31.114  -56.408 -148.450 1.00 64.55  ? 200 TYR A C   1 
ATOM 1330 O O   . TYR A 1 200 ? 30.613  -57.428 -147.973 1.00 75.22  ? 200 TYR A O   1 
ATOM 1331 C CB  . TYR A 1 200 ? 30.680  -54.030 -147.788 1.00 68.63  ? 200 TYR A CB  1 
ATOM 1332 C CG  . TYR A 1 200 ? 29.236  -54.224 -147.419 1.00 66.01  ? 200 TYR A CG  1 
ATOM 1333 C CD1 . TYR A 1 200 ? 28.836  -54.237 -146.097 1.00 65.92  ? 200 TYR A CD1 1 
ATOM 1334 C CD2 . TYR A 1 200 ? 28.274  -54.400 -148.395 1.00 71.93  ? 200 TYR A CD2 1 
ATOM 1335 C CE1 . TYR A 1 200 ? 27.520  -54.417 -145.760 1.00 71.49  ? 200 TYR A CE1 1 
ATOM 1336 C CE2 . TYR A 1 200 ? 26.957  -54.580 -148.067 1.00 74.54  ? 200 TYR A CE2 1 
ATOM 1337 C CZ  . TYR A 1 200 ? 26.585  -54.589 -146.750 1.00 76.19  ? 200 TYR A CZ  1 
ATOM 1338 O OH  . TYR A 1 200 ? 25.265  -54.770 -146.424 1.00 79.75  ? 200 TYR A OH  1 
ATOM 1339 N N   . PHE A 1 201 ? 31.294  -56.267 -149.757 1.00 60.95  ? 201 PHE A N   1 
ATOM 1340 C CA  . PHE A 1 201 ? 30.926  -57.326 -150.682 1.00 62.28  ? 201 PHE A CA  1 
ATOM 1341 C C   . PHE A 1 201 ? 32.051  -58.343 -150.782 1.00 68.86  ? 201 PHE A C   1 
ATOM 1342 O O   . PHE A 1 201 ? 33.222  -57.980 -150.915 1.00 74.85  ? 201 PHE A O   1 
ATOM 1343 C CB  . PHE A 1 201 ? 30.626  -56.753 -152.064 1.00 57.58  ? 201 PHE A CB  1 
ATOM 1344 C CG  . PHE A 1 201 ? 29.600  -55.665 -152.062 1.00 57.49  ? 201 PHE A CG  1 
ATOM 1345 C CD1 . PHE A 1 201 ? 28.286  -55.935 -151.752 1.00 63.33  ? 201 PHE A CD1 1 
ATOM 1346 C CD2 . PHE A 1 201 ? 29.952  -54.371 -152.378 1.00 65.24  ? 201 PHE A CD2 1 
ATOM 1347 C CE1 . PHE A 1 201 ? 27.345  -54.934 -151.754 1.00 66.89  ? 201 PHE A CE1 1 
ATOM 1348 C CE2 . PHE A 1 201 ? 29.016  -53.368 -152.380 1.00 61.67  ? 201 PHE A CE2 1 
ATOM 1349 C CZ  . PHE A 1 201 ? 27.711  -53.650 -152.067 1.00 58.56  ? 201 PHE A CZ  1 
ATOM 1350 N N   . ILE A 1 202 ? 31.699  -59.623 -150.720 1.00 62.18  ? 202 ILE A N   1 
ATOM 1351 C CA  . ILE A 1 202 ? 32.678  -60.694 -150.826 1.00 67.01  ? 202 ILE A CA  1 
ATOM 1352 C C   . ILE A 1 202 ? 32.206  -61.719 -151.845 1.00 65.95  ? 202 ILE A C   1 
ATOM 1353 O O   . ILE A 1 202 ? 31.039  -62.123 -151.847 1.00 65.09  ? 202 ILE A O   1 
ATOM 1354 C CB  . ILE A 1 202 ? 32.958  -61.359 -149.463 1.00 64.61  ? 202 ILE A CB  1 
ATOM 1355 C CG1 . ILE A 1 202 ? 34.026  -62.439 -149.616 1.00 67.13  ? 202 ILE A CG1 1 
ATOM 1356 C CG2 . ILE A 1 202 ? 31.694  -61.925 -148.864 1.00 63.44  ? 202 ILE A CG2 1 
ATOM 1357 C CD1 . ILE A 1 202 ? 34.456  -63.054 -148.313 1.00 64.84  ? 202 ILE A CD1 1 
ATOM 1358 N N   . SER A 1 203 ? 33.116  -62.116 -152.728 1.00 64.02  ? 203 SER A N   1 
ATOM 1359 C CA  . SER A 1 203 ? 32.887  -63.193 -153.676 1.00 61.62  ? 203 SER A CA  1 
ATOM 1360 C C   . SER A 1 203 ? 34.134  -64.057 -153.717 1.00 71.50  ? 203 SER A C   1 
ATOM 1361 O O   . SER A 1 203 ? 35.235  -63.590 -153.418 1.00 76.89  ? 203 SER A O   1 
ATOM 1362 C CB  . SER A 1 203 ? 32.559  -62.660 -155.070 1.00 68.20  ? 203 SER A CB  1 
ATOM 1363 O OG  . SER A 1 203 ? 33.437  -61.608 -155.420 1.00 76.91  ? 203 SER A OG  1 
ATOM 1364 N N   . ALA A 1 204 ? 33.961  -65.321 -154.082 1.00 78.79  ? 204 ALA A N   1 
ATOM 1365 C CA  . ALA A 1 204 ? 35.044  -66.287 -154.020 1.00 72.44  ? 204 ALA A CA  1 
ATOM 1366 C C   . ALA A 1 204 ? 35.265  -66.941 -155.375 1.00 73.66  ? 204 ALA A C   1 
ATOM 1367 O O   . ALA A 1 204 ? 34.318  -67.217 -156.115 1.00 80.79  ? 204 ALA A O   1 
ATOM 1368 C CB  . ALA A 1 204 ? 34.762  -67.362 -152.973 1.00 71.93  ? 204 ALA A CB  1 
ATOM 1369 N N   . GLU A 1 205 ? 36.537  -67.185 -155.690 1.00 91.57  ? 205 GLU A N   1 
ATOM 1370 C CA  . GLU A 1 205 ? 36.879  -67.905 -156.910 1.00 89.95  ? 205 GLU A CA  1 
ATOM 1371 C C   . GLU A 1 205 ? 36.395  -69.345 -156.857 1.00 92.24  ? 205 GLU A C   1 
ATOM 1372 O O   . GLU A 1 205 ? 35.937  -69.891 -157.867 1.00 96.46  ? 205 GLU A O   1 
ATOM 1373 C CB  . GLU A 1 205 ? 38.387  -67.859 -157.136 1.00 95.88  ? 205 GLU A CB  1 
ATOM 1374 C CG  . GLU A 1 205 ? 38.861  -68.752 -158.262 1.00 100.91 ? 205 GLU A CG  1 
ATOM 1375 C CD  . GLU A 1 205 ? 40.366  -68.815 -158.367 1.00 108.30 ? 205 GLU A CD  1 
ATOM 1376 O OE1 . GLU A 1 205 ? 41.044  -68.150 -157.560 1.00 107.68 ? 205 GLU A OE1 1 
ATOM 1377 O OE2 . GLU A 1 205 ? 40.872  -69.529 -159.258 1.00 105.46 ? 205 GLU A OE2 1 
ATOM 1378 N N   . ASP A 1 206 ? 36.496  -69.978 -155.693 1.00 98.19  ? 206 ASP A N   1 
ATOM 1379 C CA  . ASP A 1 206 ? 36.128  -71.379 -155.563 1.00 100.62 ? 206 ASP A CA  1 
ATOM 1380 C C   . ASP A 1 206 ? 34.628  -71.553 -155.768 1.00 102.44 ? 206 ASP A C   1 
ATOM 1381 O O   . ASP A 1 206 ? 33.827  -70.777 -155.241 1.00 106.66 ? 206 ASP A O   1 
ATOM 1382 C CB  . ASP A 1 206 ? 36.538  -71.897 -154.188 1.00 101.64 ? 206 ASP A CB  1 
ATOM 1383 C CG  . ASP A 1 206 ? 36.644  -73.401 -154.144 1.00 107.39 ? 206 ASP A CG  1 
ATOM 1384 O OD1 . ASP A 1 206 ? 36.739  -74.014 -155.226 1.00 108.74 ? 206 ASP A OD1 1 
ATOM 1385 O OD2 . ASP A 1 206 ? 36.626  -73.969 -153.032 1.00 108.35 ? 206 ASP A OD2 1 
ATOM 1386 N N   . ARG A 1 207 ? 34.247  -72.578 -156.528 1.00 87.98  ? 207 ARG A N   1 
ATOM 1387 C CA  . ARG A 1 207 ? 32.847  -72.809 -156.863 1.00 86.43  ? 207 ARG A CA  1 
ATOM 1388 C C   . ARG A 1 207 ? 32.377  -74.195 -156.442 1.00 90.54  ? 207 ARG A C   1 
ATOM 1389 O O   . ARG A 1 207 ? 31.385  -74.702 -156.966 1.00 95.31  ? 207 ARG A O   1 
ATOM 1390 C CB  . ARG A 1 207 ? 32.606  -72.606 -158.356 1.00 83.72  ? 207 ARG A CB  1 
ATOM 1391 C CG  . ARG A 1 207 ? 33.034  -71.253 -158.858 1.00 85.99  ? 207 ARG A CG  1 
ATOM 1392 C CD  . ARG A 1 207 ? 31.854  -70.495 -159.409 1.00 82.79  ? 207 ARG A CD  1 
ATOM 1393 N NE  . ARG A 1 207 ? 32.098  -69.059 -159.411 1.00 85.99  ? 207 ARG A NE  1 
ATOM 1394 C CZ  . ARG A 1 207 ? 31.206  -68.157 -159.034 1.00 92.26  ? 207 ARG A CZ  1 
ATOM 1395 N NH1 . ARG A 1 207 ? 30.016  -68.514 -158.585 1.00 98.81  ? 207 ARG A NH1 1 
ATOM 1396 N NH2 . ARG A 1 207 ? 31.519  -66.868 -159.097 1.00 93.83  ? 207 ARG A NH2 1 
ATOM 1397 N N   . THR A 1 208 ? 33.068  -74.823 -155.501 1.00 85.90  ? 208 THR A N   1 
ATOM 1398 C CA  . THR A 1 208 ? 32.594  -76.092 -154.978 1.00 87.81  ? 208 THR A CA  1 
ATOM 1399 C C   . THR A 1 208 ? 31.362  -75.866 -154.116 1.00 91.07  ? 208 THR A C   1 
ATOM 1400 O O   . THR A 1 208 ? 31.209  -74.822 -153.478 1.00 96.42  ? 208 THR A O   1 
ATOM 1401 C CB  . THR A 1 208 ? 33.675  -76.789 -154.158 1.00 89.53  ? 208 THR A CB  1 
ATOM 1402 O OG1 . THR A 1 208 ? 33.693  -76.246 -152.834 1.00 88.45  ? 208 THR A OG1 1 
ATOM 1403 C CG2 . THR A 1 208 ? 35.029  -76.589 -154.795 1.00 91.13  ? 208 THR A CG2 1 
ATOM 1404 N N   . GLN A 1 209 ? 30.473  -76.857 -154.109 1.00 88.09  ? 209 GLN A N   1 
ATOM 1405 C CA  . GLN A 1 209 ? 29.235  -76.726 -153.351 1.00 88.35  ? 209 GLN A CA  1 
ATOM 1406 C C   . GLN A 1 209 ? 29.515  -76.579 -151.863 1.00 91.91  ? 209 GLN A C   1 
ATOM 1407 O O   . GLN A 1 209 ? 28.916  -75.737 -151.184 1.00 93.04  ? 209 GLN A O   1 
ATOM 1408 C CB  . GLN A 1 209 ? 28.336  -77.930 -153.611 1.00 86.86  ? 209 GLN A CB  1 
ATOM 1409 C CG  . GLN A 1 209 ? 27.281  -78.137 -152.552 1.00 91.98  ? 209 GLN A CG  1 
ATOM 1410 C CD  . GLN A 1 209 ? 26.405  -79.333 -152.841 1.00 99.56  ? 209 GLN A CD  1 
ATOM 1411 O OE1 . GLN A 1 209 ? 26.240  -79.729 -153.995 1.00 102.25 ? 209 GLN A OE1 1 
ATOM 1412 N NE2 . GLN A 1 209 ? 25.839  -79.919 -151.793 1.00 98.65  ? 209 GLN A NE2 1 
ATOM 1413 N N   . GLN A 1 210 ? 30.436  -77.386 -151.338 1.00 91.43  ? 210 GLN A N   1 
ATOM 1414 C CA  . GLN A 1 210 ? 30.713  -77.360 -149.907 1.00 92.73  ? 210 GLN A CA  1 
ATOM 1415 C C   . GLN A 1 210 ? 31.293  -76.019 -149.481 1.00 95.62  ? 210 GLN A C   1 
ATOM 1416 O O   . GLN A 1 210 ? 30.861  -75.431 -148.480 1.00 98.19  ? 210 GLN A O   1 
ATOM 1417 C CB  . GLN A 1 210 ? 31.661  -78.498 -149.539 1.00 90.10  ? 210 GLN A CB  1 
ATOM 1418 C CG  . GLN A 1 210 ? 32.340  -78.323 -148.197 1.00 94.09  ? 210 GLN A CG  1 
ATOM 1419 C CD  . GLN A 1 210 ? 32.946  -79.612 -147.686 1.00 99.00  ? 210 GLN A CD  1 
ATOM 1420 O OE1 . GLN A 1 210 ? 32.374  -80.280 -146.825 1.00 99.95  ? 210 GLN A OE1 1 
ATOM 1421 N NE2 . GLN A 1 210 ? 34.108  -79.971 -148.216 1.00 97.76  ? 210 GLN A NE2 1 
ATOM 1422 N N   . PHE A 1 211 ? 32.276  -75.516 -150.231 1.00 84.33  ? 211 PHE A N   1 
ATOM 1423 C CA  . PHE A 1 211 ? 32.893  -74.248 -149.861 1.00 85.21  ? 211 PHE A CA  1 
ATOM 1424 C C   . PHE A 1 211 ? 31.893  -73.107 -149.935 1.00 82.45  ? 211 PHE A C   1 
ATOM 1425 O O   . PHE A 1 211 ? 31.857  -72.253 -149.047 1.00 80.45  ? 211 PHE A O   1 
ATOM 1426 C CB  . PHE A 1 211 ? 34.093  -73.945 -150.754 1.00 83.80  ? 211 PHE A CB  1 
ATOM 1427 C CG  . PHE A 1 211 ? 34.692  -72.592 -150.509 1.00 83.88  ? 211 PHE A CG  1 
ATOM 1428 C CD1 . PHE A 1 211 ? 35.427  -72.344 -149.365 1.00 86.40  ? 211 PHE A CD1 1 
ATOM 1429 C CD2 . PHE A 1 211 ? 34.511  -71.566 -151.412 1.00 80.41  ? 211 PHE A CD2 1 
ATOM 1430 C CE1 . PHE A 1 211 ? 35.976  -71.103 -149.132 1.00 81.36  ? 211 PHE A CE1 1 
ATOM 1431 C CE2 . PHE A 1 211 ? 35.060  -70.323 -151.183 1.00 79.71  ? 211 PHE A CE2 1 
ATOM 1432 C CZ  . PHE A 1 211 ? 35.791  -70.091 -150.043 1.00 77.74  ? 211 PHE A CZ  1 
ATOM 1433 N N   . VAL A 1 212 ? 31.078  -73.070 -150.989 1.00 81.94  ? 212 VAL A N   1 
ATOM 1434 C CA  . VAL A 1 212 ? 30.099  -71.996 -151.121 1.00 83.09  ? 212 VAL A CA  1 
ATOM 1435 C C   . VAL A 1 212 ? 29.090  -72.053 -149.984 1.00 85.59  ? 212 VAL A C   1 
ATOM 1436 O O   . VAL A 1 212 ? 28.751  -71.026 -149.382 1.00 90.11  ? 212 VAL A O   1 
ATOM 1437 C CB  . VAL A 1 212 ? 29.410  -72.068 -152.495 1.00 79.77  ? 212 VAL A CB  1 
ATOM 1438 C CG1 . VAL A 1 212 ? 28.171  -71.199 -152.505 1.00 82.36  ? 212 VAL A CG1 1 
ATOM 1439 C CG2 . VAL A 1 212 ? 30.367  -71.636 -153.585 1.00 78.45  ? 212 VAL A CG2 1 
ATOM 1440 N N   . LEU A 1 213 ? 28.597  -73.252 -149.669 1.00 79.10  ? 213 LEU A N   1 
ATOM 1441 C CA  . LEU A 1 213 ? 27.613  -73.382 -148.602 1.00 79.59  ? 213 LEU A CA  1 
ATOM 1442 C C   . LEU A 1 213 ? 28.191  -72.929 -147.268 1.00 83.07  ? 213 LEU A C   1 
ATOM 1443 O O   . LEU A 1 213 ? 27.563  -72.156 -146.535 1.00 84.04  ? 213 LEU A O   1 
ATOM 1444 C CB  . LEU A 1 213 ? 27.128  -74.826 -148.516 1.00 79.06  ? 213 LEU A CB  1 
ATOM 1445 C CG  . LEU A 1 213 ? 25.819  -75.152 -149.232 1.00 81.95  ? 213 LEU A CG  1 
ATOM 1446 C CD1 . LEU A 1 213 ? 24.639  -74.738 -148.377 1.00 84.18  ? 213 LEU A CD1 1 
ATOM 1447 C CD2 . LEU A 1 213 ? 25.758  -74.492 -150.597 1.00 82.91  ? 213 LEU A CD2 1 
ATOM 1448 N N   . ALA A 1 214 ? 29.404  -73.382 -146.945 1.00 82.34  ? 214 ALA A N   1 
ATOM 1449 C CA  . ALA A 1 214 ? 30.014  -72.985 -145.681 1.00 86.29  ? 214 ALA A CA  1 
ATOM 1450 C C   . ALA A 1 214 ? 30.312  -71.490 -145.653 1.00 86.52  ? 214 ALA A C   1 
ATOM 1451 O O   . ALA A 1 214 ? 30.124  -70.833 -144.621 1.00 88.04  ? 214 ALA A O   1 
ATOM 1452 C CB  . ALA A 1 214 ? 31.286  -73.794 -145.436 1.00 87.44  ? 214 ALA A CB  1 
ATOM 1453 N N   . MET A 1 215 ? 30.779  -70.937 -146.773 1.00 85.96  ? 215 MET A N   1 
ATOM 1454 C CA  . MET A 1 215 ? 31.102  -69.518 -146.835 1.00 88.01  ? 215 MET A CA  1 
ATOM 1455 C C   . MET A 1 215 ? 29.864  -68.675 -146.587 1.00 89.14  ? 215 MET A C   1 
ATOM 1456 O O   . MET A 1 215 ? 29.895  -67.714 -145.812 1.00 92.95  ? 215 MET A O   1 
ATOM 1457 C CB  . MET A 1 215 ? 31.702  -69.194 -148.203 1.00 90.33  ? 215 MET A CB  1 
ATOM 1458 C CG  . MET A 1 215 ? 31.901  -67.719 -148.488 1.00 89.30  ? 215 MET A CG  1 
ATOM 1459 S SD  . MET A 1 215 ? 33.473  -67.129 -147.848 1.00 106.50 ? 215 MET A SD  1 
ATOM 1460 C CE  . MET A 1 215 ? 32.945  -66.291 -146.370 1.00 90.75  ? 215 MET A CE  1 
ATOM 1461 N N   . ALA A 1 216 ? 28.752  -69.030 -147.235 1.00 80.65  ? 216 ALA A N   1 
ATOM 1462 C CA  . ALA A 1 216 ? 27.507  -68.310 -147.002 1.00 79.06  ? 216 ALA A CA  1 
ATOM 1463 C C   . ALA A 1 216 ? 27.043  -68.478 -145.565 1.00 87.47  ? 216 ALA A C   1 
ATOM 1464 O O   . ALA A 1 216 ? 26.535  -67.530 -144.953 1.00 87.85  ? 216 ALA A O   1 
ATOM 1465 C CB  . ALA A 1 216 ? 26.433  -68.789 -147.975 1.00 79.86  ? 216 ALA A CB  1 
ATOM 1466 N N   . SER A 1 217 ? 27.212  -69.679 -145.008 1.00 91.59  ? 217 SER A N   1 
ATOM 1467 C CA  . SER A 1 217 ? 26.810  -69.921 -143.628 1.00 86.21  ? 217 SER A CA  1 
ATOM 1468 C C   . SER A 1 217 ? 27.559  -69.007 -142.670 1.00 85.43  ? 217 SER A C   1 
ATOM 1469 O O   . SER A 1 217 ? 26.973  -68.469 -141.726 1.00 87.83  ? 217 SER A O   1 
ATOM 1470 C CB  . SER A 1 217 ? 27.057  -71.384 -143.266 1.00 85.32  ? 217 SER A CB  1 
ATOM 1471 O OG  . SER A 1 217 ? 26.047  -72.220 -143.795 1.00 92.46  ? 217 SER A OG  1 
ATOM 1472 N N   . GLU A 1 218 ? 28.857  -68.832 -142.889 1.00 87.45  ? 218 GLU A N   1 
ATOM 1473 C CA  . GLU A 1 218 ? 29.642  -67.983 -142.001 1.00 85.37  ? 218 GLU A CA  1 
ATOM 1474 C C   . GLU A 1 218 ? 29.430  -66.501 -142.275 1.00 88.55  ? 218 GLU A C   1 
ATOM 1475 O O   . GLU A 1 218 ? 29.593  -65.683 -141.364 1.00 94.37  ? 218 GLU A O   1 
ATOM 1476 C CB  . GLU A 1 218 ? 31.118  -68.342 -142.107 1.00 87.45  ? 218 GLU A CB  1 
ATOM 1477 C CG  . GLU A 1 218 ? 31.341  -69.826 -141.990 1.00 94.80  ? 218 GLU A CG  1 
ATOM 1478 C CD  . GLU A 1 218 ? 32.782  -70.188 -141.776 1.00 100.77 ? 218 GLU A CD  1 
ATOM 1479 O OE1 . GLU A 1 218 ? 33.474  -69.450 -141.044 1.00 98.82  ? 218 GLU A OE1 1 
ATOM 1480 O OE2 . GLU A 1 218 ? 33.215  -71.214 -142.339 1.00 101.37 ? 218 GLU A OE2 1 
ATOM 1481 N N   . ILE A 1 219 ? 29.089  -66.129 -143.508 1.00 73.38  ? 219 ILE A N   1 
ATOM 1482 C CA  . ILE A 1 219 ? 28.774  -64.732 -143.780 1.00 66.91  ? 219 ILE A CA  1 
ATOM 1483 C C   . ILE A 1 219 ? 27.465  -64.342 -143.112 1.00 71.09  ? 219 ILE A C   1 
ATOM 1484 O O   . ILE A 1 219 ? 27.333  -63.239 -142.570 1.00 76.53  ? 219 ILE A O   1 
ATOM 1485 C CB  . ILE A 1 219 ? 28.737  -64.473 -145.295 1.00 68.88  ? 219 ILE A CB  1 
ATOM 1486 C CG1 . ILE A 1 219 ? 30.151  -64.327 -145.836 1.00 69.25  ? 219 ILE A CG1 1 
ATOM 1487 C CG2 . ILE A 1 219 ? 27.942  -63.227 -145.605 1.00 73.21  ? 219 ILE A CG2 1 
ATOM 1488 C CD1 . ILE A 1 219 ? 30.782  -63.006 -145.509 1.00 71.15  ? 219 ILE A CD1 1 
ATOM 1489 N N   . GLN A 1 220 ? 26.483  -65.246 -143.121 1.00 72.43  ? 220 GLN A N   1 
ATOM 1490 C CA  . GLN A 1 220 ? 25.170  -64.931 -142.571 1.00 72.47  ? 220 GLN A CA  1 
ATOM 1491 C C   . GLN A 1 220 ? 25.256  -64.455 -141.128 1.00 78.90  ? 220 GLN A C   1 
ATOM 1492 O O   . GLN A 1 220 ? 24.448  -63.628 -140.696 1.00 85.70  ? 220 GLN A O   1 
ATOM 1493 C CB  . GLN A 1 220 ? 24.261  -66.153 -142.678 1.00 77.97  ? 220 GLN A CB  1 
ATOM 1494 C CG  . GLN A 1 220 ? 22.978  -66.058 -141.886 1.00 79.64  ? 220 GLN A CG  1 
ATOM 1495 C CD  . GLN A 1 220 ? 21.938  -65.211 -142.572 1.00 77.99  ? 220 GLN A CD  1 
ATOM 1496 O OE1 . GLN A 1 220 ? 22.092  -64.839 -143.733 1.00 78.22  ? 220 GLN A OE1 1 
ATOM 1497 N NE2 . GLN A 1 220 ? 20.863  -64.905 -141.860 1.00 78.10  ? 220 GLN A NE2 1 
ATOM 1498 N N   . ALA A 1 221 ? 26.236  -64.943 -140.373 1.00 77.09  ? 221 ALA A N   1 
ATOM 1499 C CA  . ALA A 1 221 ? 26.405  -64.504 -138.997 1.00 78.83  ? 221 ALA A CA  1 
ATOM 1500 C C   . ALA A 1 221 ? 27.056  -63.133 -138.886 1.00 74.96  ? 221 ALA A C   1 
ATOM 1501 O O   . ALA A 1 221 ? 27.147  -62.600 -137.777 1.00 75.20  ? 221 ALA A O   1 
ATOM 1502 C CB  . ALA A 1 221 ? 27.234  -65.522 -138.213 1.00 78.70  ? 221 ALA A CB  1 
ATOM 1503 N N   . ARG A 1 222 ? 27.507  -62.556 -139.989 1.00 78.06  ? 222 ARG A N   1 
ATOM 1504 C CA  . ARG A 1 222 ? 28.238  -61.298 -139.974 1.00 78.91  ? 222 ARG A CA  1 
ATOM 1505 C C   . ARG A 1 222 ? 27.420  -60.203 -140.647 1.00 78.28  ? 222 ARG A C   1 
ATOM 1506 O O   . ARG A 1 222 ? 26.276  -60.405 -141.054 1.00 82.30  ? 222 ARG A O   1 
ATOM 1507 C CB  . ARG A 1 222 ? 29.597  -61.461 -140.653 1.00 77.38  ? 222 ARG A CB  1 
ATOM 1508 C CG  . ARG A 1 222 ? 30.544  -62.339 -139.875 1.00 76.71  ? 222 ARG A CG  1 
ATOM 1509 C CD  . ARG A 1 222 ? 31.740  -62.743 -140.701 1.00 77.73  ? 222 ARG A CD  1 
ATOM 1510 N NE  . ARG A 1 222 ? 32.802  -63.270 -139.857 1.00 79.63  ? 222 ARG A NE  1 
ATOM 1511 C CZ  . ARG A 1 222 ? 32.784  -64.471 -139.296 1.00 82.50  ? 222 ARG A CZ  1 
ATOM 1512 N NH1 . ARG A 1 222 ? 31.775  -65.304 -139.480 1.00 84.35  ? 222 ARG A NH1 1 
ATOM 1513 N NH2 . ARG A 1 222 ? 33.803  -64.842 -138.528 1.00 85.77  ? 222 ARG A NH2 1 
ATOM 1514 N N   . LYS A 1 223 ? 28.029  -59.026 -140.757 1.00 64.29  ? 223 LYS A N   1 
ATOM 1515 C CA  . LYS A 1 223 ? 27.386  -57.844 -141.326 1.00 64.77  ? 223 LYS A CA  1 
ATOM 1516 C C   . LYS A 1 223 ? 27.873  -57.555 -142.736 1.00 71.83  ? 223 LYS A C   1 
ATOM 1517 O O   . LYS A 1 223 ? 28.106  -56.399 -143.093 1.00 80.32  ? 223 LYS A O   1 
ATOM 1518 C CB  . LYS A 1 223 ? 27.614  -56.638 -140.424 1.00 67.12  ? 223 LYS A CB  1 
ATOM 1519 C CG  . LYS A 1 223 ? 27.079  -56.816 -139.023 1.00 73.34  ? 223 LYS A CG  1 
ATOM 1520 C CD  . LYS A 1 223 ? 25.919  -55.871 -138.777 1.00 76.37  ? 223 LYS A CD  1 
ATOM 1521 C CE  . LYS A 1 223 ? 25.353  -56.033 -137.383 1.00 77.12  ? 223 LYS A CE  1 
ATOM 1522 N NZ  . LYS A 1 223 ? 23.962  -55.514 -137.305 1.00 75.57  ? 223 LYS A NZ  1 
ATOM 1523 N N   . LYS A 1 224 ? 28.053  -58.586 -143.554 1.00 64.85  ? 224 LYS A N   1 
ATOM 1524 C CA  . LYS A 1 224 ? 28.552  -58.420 -144.909 1.00 65.48  ? 224 LYS A CA  1 
ATOM 1525 C C   . LYS A 1 224 ? 27.701  -59.249 -145.859 1.00 69.33  ? 224 LYS A C   1 
ATOM 1526 O O   . LYS A 1 224 ? 26.938  -60.121 -145.442 1.00 77.03  ? 224 LYS A O   1 
ATOM 1527 C CB  . LYS A 1 224 ? 30.029  -58.808 -144.996 1.00 65.79  ? 224 LYS A CB  1 
ATOM 1528 C CG  . LYS A 1 224 ? 30.934  -57.866 -144.225 1.00 64.35  ? 224 LYS A CG  1 
ATOM 1529 C CD  . LYS A 1 224 ? 32.238  -58.529 -143.849 1.00 67.43  ? 224 LYS A CD  1 
ATOM 1530 C CE  . LYS A 1 224 ? 32.947  -57.762 -142.754 1.00 69.07  ? 224 LYS A CE  1 
ATOM 1531 N NZ  . LYS A 1 224 ? 32.635  -56.312 -142.821 1.00 71.99  ? 224 LYS A NZ  1 
ATOM 1532 N N   . ILE A 1 225 ? 27.826  -58.960 -147.151 1.00 69.29  ? 225 ILE A N   1 
ATOM 1533 C CA  . ILE A 1 225 ? 27.030  -59.602 -148.190 1.00 67.95  ? 225 ILE A CA  1 
ATOM 1534 C C   . ILE A 1 225 ? 27.947  -60.443 -149.063 1.00 72.73  ? 225 ILE A C   1 
ATOM 1535 O O   . ILE A 1 225 ? 28.992  -59.963 -149.521 1.00 71.10  ? 225 ILE A O   1 
ATOM 1536 C CB  . ILE A 1 225 ? 26.269  -58.570 -149.037 1.00 63.69  ? 225 ILE A CB  1 
ATOM 1537 C CG1 . ILE A 1 225 ? 25.143  -57.940 -148.224 1.00 68.34  ? 225 ILE A CG1 1 
ATOM 1538 C CG2 . ILE A 1 225 ? 25.710  -59.218 -150.284 1.00 62.95  ? 225 ILE A CG2 1 
ATOM 1539 C CD1 . ILE A 1 225 ? 24.238  -57.057 -149.038 1.00 69.49  ? 225 ILE A CD1 1 
ATOM 1540 N N   . PHE A 1 226 ? 27.554  -61.690 -149.298 1.00 73.67  ? 226 PHE A N   1 
ATOM 1541 C CA  . PHE A 1 226 ? 28.317  -62.632 -150.105 1.00 67.01  ? 226 PHE A CA  1 
ATOM 1542 C C   . PHE A 1 226 ? 27.626  -62.799 -151.452 1.00 67.53  ? 226 PHE A C   1 
ATOM 1543 O O   . PHE A 1 226 ? 26.474  -63.236 -151.512 1.00 71.90  ? 226 PHE A O   1 
ATOM 1544 C CB  . PHE A 1 226 ? 28.442  -63.971 -149.380 1.00 67.95  ? 226 PHE A CB  1 
ATOM 1545 C CG  . PHE A 1 226 ? 28.962  -65.086 -150.235 1.00 71.12  ? 226 PHE A CG  1 
ATOM 1546 C CD1 . PHE A 1 226 ? 30.189  -64.993 -150.851 1.00 70.88  ? 226 PHE A CD1 1 
ATOM 1547 C CD2 . PHE A 1 226 ? 28.232  -66.247 -150.389 1.00 75.02  ? 226 PHE A CD2 1 
ATOM 1548 C CE1 . PHE A 1 226 ? 30.667  -66.028 -151.623 1.00 67.45  ? 226 PHE A CE1 1 
ATOM 1549 C CE2 . PHE A 1 226 ? 28.709  -67.281 -151.160 1.00 69.08  ? 226 PHE A CE2 1 
ATOM 1550 C CZ  . PHE A 1 226 ? 29.925  -67.169 -151.777 1.00 66.32  ? 226 PHE A CZ  1 
ATOM 1551 N N   . PHE A 1 227 ? 28.332  -62.456 -152.523 1.00 65.98  ? 227 PHE A N   1 
ATOM 1552 C CA  . PHE A 1 227 ? 27.804  -62.527 -153.877 1.00 64.90  ? 227 PHE A CA  1 
ATOM 1553 C C   . PHE A 1 227 ? 28.369  -63.755 -154.571 1.00 74.97  ? 227 PHE A C   1 
ATOM 1554 O O   . PHE A 1 227 ? 29.584  -63.973 -154.558 1.00 81.77  ? 227 PHE A O   1 
ATOM 1555 C CB  . PHE A 1 227 ? 28.173  -61.272 -154.666 1.00 65.72  ? 227 PHE A CB  1 
ATOM 1556 C CG  . PHE A 1 227 ? 27.147  -60.185 -154.599 1.00 61.91  ? 227 PHE A CG  1 
ATOM 1557 C CD1 . PHE A 1 227 ? 26.073  -60.177 -155.463 1.00 67.45  ? 227 PHE A CD1 1 
ATOM 1558 C CD2 . PHE A 1 227 ? 27.256  -59.172 -153.670 1.00 63.38  ? 227 PHE A CD2 1 
ATOM 1559 C CE1 . PHE A 1 227 ? 25.135  -59.175 -155.405 1.00 69.05  ? 227 PHE A CE1 1 
ATOM 1560 C CE2 . PHE A 1 227 ? 26.319  -58.169 -153.609 1.00 65.55  ? 227 PHE A CE2 1 
ATOM 1561 C CZ  . PHE A 1 227 ? 25.258  -58.171 -154.476 1.00 69.50  ? 227 PHE A CZ  1 
ATOM 1562 N N   . THR A 1 228 ? 27.496  -64.548 -155.184 1.00 72.88  ? 228 THR A N   1 
ATOM 1563 C CA  . THR A 1 228 ? 27.923  -65.772 -155.838 1.00 67.27  ? 228 THR A CA  1 
ATOM 1564 C C   . THR A 1 228 ? 27.163  -65.948 -157.141 1.00 72.74  ? 228 THR A C   1 
ATOM 1565 O O   . THR A 1 228 ? 26.147  -65.296 -157.388 1.00 86.80  ? 228 THR A O   1 
ATOM 1566 C CB  . THR A 1 228 ? 27.716  -66.995 -154.943 1.00 69.92  ? 228 THR A CB  1 
ATOM 1567 O OG1 . THR A 1 228 ? 28.535  -68.071 -155.413 1.00 74.72  ? 228 THR A OG1 1 
ATOM 1568 C CG2 . THR A 1 228 ? 26.268  -67.432 -154.970 1.00 74.02  ? 228 THR A CG2 1 
ATOM 1569 N N   . ALA A 1 229 ? 27.676  -66.841 -157.977 1.00 73.66  ? 229 ALA A N   1 
ATOM 1570 C CA  . ALA A 1 229 ? 27.068  -67.175 -159.252 1.00 78.13  ? 229 ALA A CA  1 
ATOM 1571 C C   . ALA A 1 229 ? 27.034  -68.689 -159.397 1.00 85.19  ? 229 ALA A C   1 
ATOM 1572 O O   . ALA A 1 229 ? 27.746  -69.413 -158.699 1.00 92.20  ? 229 ALA A O   1 
ATOM 1573 C CB  . ALA A 1 229 ? 27.828  -66.546 -160.423 1.00 76.08  ? 229 ALA A CB  1 
ATOM 1574 N N   . ASN A 1 230 ? 26.187  -69.168 -160.302 1.00 84.32  ? 230 ASN A N   1 
ATOM 1575 C CA  . ASN A 1 230 ? 26.030  -70.599 -160.501 1.00 80.29  ? 230 ASN A CA  1 
ATOM 1576 C C   . ASN A 1 230 ? 25.603  -70.869 -161.934 1.00 86.54  ? 230 ASN A C   1 
ATOM 1577 O O   . ASN A 1 230 ? 25.027  -70.010 -162.604 1.00 91.62  ? 230 ASN A O   1 
ATOM 1578 C CB  . ASN A 1 230 ? 25.009  -71.186 -159.525 1.00 79.25  ? 230 ASN A CB  1 
ATOM 1579 C CG  . ASN A 1 230 ? 25.075  -72.690 -159.456 1.00 85.29  ? 230 ASN A CG  1 
ATOM 1580 O OD1 . ASN A 1 230 ? 25.024  -73.372 -160.478 1.00 88.15  ? 230 ASN A OD1 1 
ATOM 1581 N ND2 . ASN A 1 230 ? 25.186  -73.221 -158.248 1.00 88.16  ? 230 ASN A ND2 1 
ATOM 1582 N N   . ALA A 1 231 ? 25.907  -72.077 -162.407 1.00 84.13  ? 231 ALA A N   1 
ATOM 1583 C CA  . ALA A 1 231 ? 25.442  -72.543 -163.708 1.00 80.54  ? 231 ALA A CA  1 
ATOM 1584 C C   . ALA A 1 231 ? 25.061  -74.014 -163.652 1.00 82.09  ? 231 ALA A C   1 
ATOM 1585 O O   . ALA A 1 231 ? 25.382  -74.788 -164.558 1.00 87.49  ? 231 ALA A O   1 
ATOM 1586 C CB  . ALA A 1 231 ? 26.492  -72.309 -164.791 1.00 80.88  ? 231 ALA A CB  1 
ATOM 1587 N N   . ASP A 1 232 ? 24.372  -74.427 -162.594 1.00 88.78  ? 232 ASP A N   1 
ATOM 1588 C CA  . ASP A 1 232 ? 23.946  -75.813 -162.458 1.00 88.62  ? 232 ASP A CA  1 
ATOM 1589 C C   . ASP A 1 232 ? 22.610  -76.013 -163.156 1.00 87.80  ? 232 ASP A C   1 
ATOM 1590 O O   . ASP A 1 232 ? 21.647  -75.292 -162.885 1.00 90.17  ? 232 ASP A O   1 
ATOM 1591 C CB  . ASP A 1 232 ? 23.839  -76.214 -160.989 1.00 89.24  ? 232 ASP A CB  1 
ATOM 1592 C CG  . ASP A 1 232 ? 23.786  -77.716 -160.800 1.00 94.72  ? 232 ASP A CG  1 
ATOM 1593 O OD1 . ASP A 1 232 ? 23.874  -78.444 -161.810 1.00 97.01  ? 232 ASP A OD1 1 
ATOM 1594 O OD2 . ASP A 1 232 ? 23.662  -78.170 -159.645 1.00 96.67  ? 232 ASP A OD2 1 
ATOM 1595 N N   . VAL A 1 233 ? 22.556  -76.999 -164.051 1.00 81.95  ? 233 VAL A N   1 
ATOM 1596 C CA  . VAL A 1 233 ? 21.337  -77.250 -164.811 1.00 80.71  ? 233 VAL A CA  1 
ATOM 1597 C C   . VAL A 1 233 ? 20.215  -77.711 -163.893 1.00 82.51  ? 233 VAL A C   1 
ATOM 1598 O O   . VAL A 1 233 ? 19.045  -77.378 -164.110 1.00 88.88  ? 233 VAL A O   1 
ATOM 1599 C CB  . VAL A 1 233 ? 21.607  -78.270 -165.928 1.00 82.13  ? 233 VAL A CB  1 
ATOM 1600 C CG1 . VAL A 1 233 ? 20.424  -78.349 -166.865 1.00 82.14  ? 233 VAL A CG1 1 
ATOM 1601 C CG2 . VAL A 1 233 ? 22.861  -77.894 -166.687 1.00 84.85  ? 233 VAL A CG2 1 
ATOM 1602 N N   . LYS A 1 234 ? 20.549  -78.480 -162.855 1.00 89.14  ? 234 LYS A N   1 
ATOM 1603 C CA  . LYS A 1 234 ? 19.526  -78.983 -161.945 1.00 89.02  ? 234 LYS A CA  1 
ATOM 1604 C C   . LYS A 1 234 ? 18.757  -77.861 -161.266 1.00 96.98  ? 234 LYS A C   1 
ATOM 1605 O O   . LYS A 1 234 ? 17.642  -78.091 -160.789 1.00 99.08  ? 234 LYS A O   1 
ATOM 1606 C CB  . LYS A 1 234 ? 20.155  -79.887 -160.886 1.00 85.93  ? 234 LYS A CB  1 
ATOM 1607 C CG  . LYS A 1 234 ? 21.325  -80.707 -161.387 1.00 90.53  ? 234 LYS A CG  1 
ATOM 1608 C CD  . LYS A 1 234 ? 20.850  -81.876 -162.231 1.00 94.16  ? 234 LYS A CD  1 
ATOM 1609 C CE  . LYS A 1 234 ? 22.021  -82.695 -162.746 1.00 98.32  ? 234 LYS A CE  1 
ATOM 1610 N NZ  . LYS A 1 234 ? 22.844  -81.944 -163.734 1.00 97.54  ? 234 LYS A NZ  1 
ATOM 1611 N N   . ALA A 1 235 ? 19.329  -76.657 -161.205 1.00 93.20  ? 235 ALA A N   1 
ATOM 1612 C CA  . ALA A 1 235 ? 18.603  -75.518 -160.660 1.00 84.85  ? 235 ALA A CA  1 
ATOM 1613 C C   . ALA A 1 235 ? 17.394  -75.150 -161.504 1.00 89.13  ? 235 ALA A C   1 
ATOM 1614 O O   . ALA A 1 235 ? 16.410  -74.641 -160.964 1.00 92.55  ? 235 ALA A O   1 
ATOM 1615 C CB  . ALA A 1 235 ? 19.530  -74.312 -160.539 1.00 82.77  ? 235 ALA A CB  1 
ATOM 1616 N N   . LEU A 1 236 ? 17.442  -75.401 -162.809 1.00 90.64  ? 236 LEU A N   1 
ATOM 1617 C CA  . LEU A 1 236 ? 16.353  -75.035 -163.699 1.00 88.84  ? 236 LEU A CA  1 
ATOM 1618 C C   . LEU A 1 236 ? 15.265  -76.094 -163.788 1.00 87.47  ? 236 LEU A C   1 
ATOM 1619 O O   . LEU A 1 236 ? 14.161  -75.784 -164.245 1.00 87.10  ? 236 LEU A O   1 
ATOM 1620 C CB  . LEU A 1 236 ? 16.892  -74.765 -165.106 1.00 87.24  ? 236 LEU A CB  1 
ATOM 1621 C CG  . LEU A 1 236 ? 18.116  -73.864 -165.223 1.00 87.74  ? 236 LEU A CG  1 
ATOM 1622 C CD1 . LEU A 1 236 ? 18.414  -73.576 -166.677 1.00 90.86  ? 236 LEU A CD1 1 
ATOM 1623 C CD2 . LEU A 1 236 ? 17.891  -72.574 -164.470 1.00 88.71  ? 236 LEU A CD2 1 
ATOM 1624 N N   . GLN A 1 237 ? 15.537  -77.324 -163.357 1.00 102.25 ? 237 GLN A N   1 
ATOM 1625 C CA  . GLN A 1 237 ? 14.593  -78.412 -163.590 1.00 104.08 ? 237 GLN A CA  1 
ATOM 1626 C C   . GLN A 1 237 ? 13.470  -78.414 -162.562 1.00 105.62 ? 237 GLN A C   1 
ATOM 1627 O O   . GLN A 1 237 ? 12.302  -78.199 -162.902 1.00 108.06 ? 237 GLN A O   1 
ATOM 1628 C CB  . GLN A 1 237 ? 15.327  -79.754 -163.577 1.00 102.40 ? 237 GLN A CB  1 
ATOM 1629 C CG  . GLN A 1 237 ? 16.608  -79.805 -164.401 1.00 108.68 ? 237 GLN A CG  1 
ATOM 1630 C CD  . GLN A 1 237 ? 16.409  -79.430 -165.860 1.00 111.77 ? 237 GLN A CD  1 
ATOM 1631 O OE1 . GLN A 1 237 ? 16.153  -78.273 -166.195 1.00 113.65 ? 237 GLN A OE1 1 
ATOM 1632 N NE2 . GLN A 1 237 ? 16.529  -80.418 -166.739 1.00 108.85 ? 237 GLN A NE2 1 
ATOM 1633 N N   . GLY A 1 238 ? 13.804  -78.644 -161.301 1.00 104.18 ? 238 GLY A N   1 
ATOM 1634 C CA  . GLY A 1 238 ? 12.790  -78.839 -160.293 1.00 105.66 ? 238 GLY A CA  1 
ATOM 1635 C C   . GLY A 1 238 ? 12.127  -77.552 -159.856 1.00 107.02 ? 238 GLY A C   1 
ATOM 1636 O O   . GLY A 1 238 ? 12.667  -76.462 -160.016 1.00 110.82 ? 238 GLY A O   1 
ATOM 1637 N N   . THR A 1 239 ? 10.926  -77.698 -159.299 1.00 103.43 ? 239 THR A N   1 
ATOM 1638 C CA  . THR A 1 239 ? 10.193  -76.583 -158.717 1.00 103.45 ? 239 THR A CA  1 
ATOM 1639 C C   . THR A 1 239 ? 9.894   -76.767 -157.240 1.00 105.87 ? 239 THR A C   1 
ATOM 1640 O O   . THR A 1 239 ? 9.863   -75.781 -156.503 1.00 106.91 ? 239 THR A O   1 
ATOM 1641 C CB  . THR A 1 239 ? 8.879   -76.354 -159.468 1.00 102.83 ? 239 THR A CB  1 
ATOM 1642 O OG1 . THR A 1 239 ? 9.118   -76.437 -160.877 1.00 102.09 ? 239 THR A OG1 1 
ATOM 1643 C CG2 . THR A 1 239 ? 8.317   -74.982 -159.146 1.00 97.77  ? 239 THR A CG2 1 
ATOM 1644 N N   . ASP A 1 240 ? 9.669   -77.998 -156.789 1.00 120.51 ? 240 ASP A N   1 
ATOM 1645 C CA  . ASP A 1 240 ? 9.540   -78.249 -155.361 1.00 124.84 ? 240 ASP A CA  1 
ATOM 1646 C C   . ASP A 1 240 ? 10.905  -78.135 -154.696 1.00 127.00 ? 240 ASP A C   1 
ATOM 1647 O O   . ASP A 1 240 ? 11.900  -78.657 -155.205 1.00 126.59 ? 240 ASP A O   1 
ATOM 1648 C CB  . ASP A 1 240 ? 8.939   -79.631 -155.115 1.00 126.98 ? 240 ASP A CB  1 
ATOM 1649 C CG  . ASP A 1 240 ? 8.584   -79.861 -153.656 1.00 128.99 ? 240 ASP A CG  1 
ATOM 1650 O OD1 . ASP A 1 240 ? 8.625   -78.894 -152.868 1.00 126.97 ? 240 ASP A OD1 1 
ATOM 1651 O OD2 . ASP A 1 240 ? 8.268   -81.014 -153.296 1.00 129.99 ? 240 ASP A OD2 1 
ATOM 1652 N N   . LEU A 1 241 ? 10.951  -77.449 -153.554 1.00 113.49 ? 241 LEU A N   1 
ATOM 1653 C CA  . LEU A 1 241 ? 12.231  -77.180 -152.911 1.00 112.64 ? 241 LEU A CA  1 
ATOM 1654 C C   . LEU A 1 241 ? 12.854  -78.443 -152.330 1.00 114.85 ? 241 LEU A C   1 
ATOM 1655 O O   . LEU A 1 241 ? 14.054  -78.681 -152.502 1.00 115.61 ? 241 LEU A O   1 
ATOM 1656 C CB  . LEU A 1 241 ? 12.058  -76.118 -151.828 1.00 110.68 ? 241 LEU A CB  1 
ATOM 1657 C CG  . LEU A 1 241 ? 12.215  -74.683 -152.324 1.00 108.15 ? 241 LEU A CG  1 
ATOM 1658 C CD1 . LEU A 1 241 ? 11.618  -73.704 -151.335 1.00 109.15 ? 241 LEU A CD1 1 
ATOM 1659 C CD2 . LEU A 1 241 ? 13.679  -74.378 -152.563 1.00 108.35 ? 241 LEU A CD2 1 
ATOM 1660 N N   . THR A 1 242 ? 12.105  -79.114 -151.454 1.00 111.46 ? 242 THR A N   1 
ATOM 1661 C CA  . THR A 1 242 ? 12.684  -80.271 -150.744 1.00 108.17 ? 242 THR A CA  1 
ATOM 1662 C C   . THR A 1 242 ? 13.348  -81.156 -151.749 1.00 109.66 ? 242 THR A C   1 
ATOM 1663 O O   . THR A 1 242 ? 14.326  -81.838 -151.393 1.00 107.43 ? 242 THR A O   1 
ATOM 1664 C CB  . THR A 1 242 ? 11.571  -81.012 -150.016 1.00 107.59 ? 242 THR A CB  1 
ATOM 1665 O OG1 . THR A 1 242 ? 10.726  -81.489 -151.058 1.00 107.37 ? 242 THR A OG1 1 
ATOM 1666 C CG2 . THR A 1 242 ? 10.786  -80.107 -149.087 1.00 108.37 ? 242 THR A CG2 1 
ATOM 1667 N N   . SER A 1 243 ? 12.844  -81.138 -152.974 1.00 126.73 ? 243 SER A N   1 
ATOM 1668 C CA  . SER A 1 243 ? 13.371  -82.063 -153.995 1.00 128.87 ? 243 SER A CA  1 
ATOM 1669 C C   . SER A 1 243 ? 14.749  -81.612 -154.471 1.00 127.81 ? 243 SER A C   1 
ATOM 1670 O O   . SER A 1 243 ? 15.597  -82.476 -154.762 1.00 127.07 ? 243 SER A O   1 
ATOM 1671 C CB  . SER A 1 243 ? 12.394  -82.116 -155.138 1.00 30.00  ? 243 SER A CB  1 
ATOM 1672 N N   . ALA A 1 244 ? 14.966  -80.303 -154.563 1.00 116.17 ? 244 ALA A N   1 
ATOM 1673 C CA  . ALA A 1 244 ? 16.245  -79.812 -155.121 1.00 114.10 ? 244 ALA A CA  1 
ATOM 1674 C C   . ALA A 1 244 ? 17.346  -79.879 -154.069 1.00 113.97 ? 244 ALA A C   1 
ATOM 1675 O O   . ALA A 1 244 ? 17.097  -79.511 -152.909 1.00 113.96 ? 244 ALA A O   1 
ATOM 1676 C CB  . ALA A 1 244 ? 16.057  -78.411 -155.626 1.00 114.84 ? 244 ALA A CB  1 
ATOM 1677 N N   . THR A 1 245 ? 18.535  -80.322 -154.477 1.00 104.98 ? 245 THR A N   1 
ATOM 1678 C CA  . THR A 1 245 ? 19.655  -80.396 -153.554 1.00 104.01 ? 245 THR A CA  1 
ATOM 1679 C C   . THR A 1 245 ? 20.916  -79.857 -154.228 1.00 107.37 ? 245 THR A C   1 
ATOM 1680 O O   . THR A 1 245 ? 22.016  -80.384 -154.081 1.00 106.64 ? 245 THR A O   1 
ATOM 1681 C CB  . THR A 1 245 ? 19.839  -81.829 -153.060 1.00 100.51 ? 245 THR A CB  1 
ATOM 1682 N N   . ASP A 1 246 ? 20.774  -78.776 -154.984 1.00 105.34 ? 246 ASP A N   1 
ATOM 1683 C CA  . ASP A 1 246 ? 21.914  -78.097 -155.578 1.00 102.45 ? 246 ASP A CA  1 
ATOM 1684 C C   . ASP A 1 246 ? 22.189  -76.797 -154.834 1.00 105.21 ? 246 ASP A C   1 
ATOM 1685 O O   . ASP A 1 246 ? 21.402  -76.373 -153.984 1.00 108.69 ? 246 ASP A O   1 
ATOM 1686 C CB  . ASP A 1 246 ? 21.681  -77.822 -157.064 1.00 101.05 ? 246 ASP A CB  1 
ATOM 1687 C CG  . ASP A 1 246 ? 20.279  -77.347 -157.355 1.00 102.77 ? 246 ASP A CG  1 
ATOM 1688 O OD1 . ASP A 1 246 ? 19.674  -76.702 -156.480 1.00 105.75 ? 246 ASP A OD1 1 
ATOM 1689 O OD2 . ASP A 1 246 ? 19.778  -77.616 -158.464 1.00 102.48 ? 246 ASP A OD2 1 
ATOM 1690 N N   . VAL A 1 247 ? 23.314  -76.170 -155.165 1.00 88.71  ? 247 VAL A N   1 
ATOM 1691 C CA  . VAL A 1 247 ? 23.816  -75.007 -154.435 1.00 83.93  ? 247 VAL A CA  1 
ATOM 1692 C C   . VAL A 1 247 ? 22.756  -73.917 -154.304 1.00 80.24  ? 247 VAL A C   1 
ATOM 1693 O O   . VAL A 1 247 ? 22.553  -73.404 -153.196 1.00 81.31  ? 247 VAL A O   1 
ATOM 1694 C CB  . VAL A 1 247 ? 25.086  -74.448 -155.095 1.00 82.65  ? 247 VAL A CB  1 
ATOM 1695 C CG1 . VAL A 1 247 ? 25.735  -73.425 -154.191 1.00 82.70  ? 247 VAL A CG1 1 
ATOM 1696 C CG2 . VAL A 1 247 ? 26.049  -75.570 -155.430 1.00 83.78  ? 247 VAL A CG2 1 
ATOM 1697 N N   . PRO A 1 248 ? 22.054  -73.524 -155.375 1.00 78.14  ? 248 PRO A N   1 
ATOM 1698 C CA  . PRO A 1 248 ? 21.036  -72.479 -155.219 1.00 78.92  ? 248 PRO A CA  1 
ATOM 1699 C C   . PRO A 1 248 ? 19.861  -72.892 -154.350 1.00 80.97  ? 248 PRO A C   1 
ATOM 1700 O O   . PRO A 1 248 ? 19.117  -72.033 -153.871 1.00 84.32  ? 248 PRO A O   1 
ATOM 1701 C CB  . PRO A 1 248 ? 20.592  -72.220 -156.662 1.00 75.62  ? 248 PRO A CB  1 
ATOM 1702 C CG  . PRO A 1 248 ? 20.896  -73.469 -157.362 1.00 82.64  ? 248 PRO A CG  1 
ATOM 1703 C CD  . PRO A 1 248 ? 22.200  -73.887 -156.793 1.00 78.01  ? 248 PRO A CD  1 
ATOM 1704 N N   . ALA A 1 249 ? 19.673  -74.194 -154.140 1.00 79.39  ? 249 ALA A N   1 
ATOM 1705 C CA  . ALA A 1 249 ? 18.497  -74.671 -153.419 1.00 78.59  ? 249 ALA A CA  1 
ATOM 1706 C C   . ALA A 1 249 ? 18.682  -74.605 -151.907 1.00 82.18  ? 249 ALA A C   1 
ATOM 1707 O O   . ALA A 1 249 ? 17.862  -74.005 -151.206 1.00 88.17  ? 249 ALA A O   1 
ATOM 1708 C CB  . ALA A 1 249 ? 18.154  -76.099 -153.848 1.00 81.80  ? 249 ALA A CB  1 
ATOM 1709 N N   . GLN A 1 250 ? 19.747  -75.224 -151.387 1.00 80.29  ? 250 GLN A N   1 
ATOM 1710 C CA  . GLN A 1 250 ? 19.925  -75.264 -149.940 1.00 85.15  ? 250 GLN A CA  1 
ATOM 1711 C C   . GLN A 1 250 ? 20.072  -73.864 -149.369 1.00 88.65  ? 250 GLN A C   1 
ATOM 1712 O O   . GLN A 1 250 ? 19.745  -73.622 -148.201 1.00 92.78  ? 250 GLN A O   1 
ATOM 1713 C CB  . GLN A 1 250 ? 21.135  -76.118 -149.566 1.00 83.45  ? 250 GLN A CB  1 
ATOM 1714 C CG  . GLN A 1 250 ? 21.261  -77.403 -150.345 1.00 87.31  ? 250 GLN A CG  1 
ATOM 1715 C CD  . GLN A 1 250 ? 22.380  -77.347 -151.353 1.00 92.76  ? 250 GLN A CD  1 
ATOM 1716 O OE1 . GLN A 1 250 ? 22.994  -76.301 -151.550 1.00 94.59  ? 250 GLN A OE1 1 
ATOM 1717 N NE2 . GLN A 1 250 ? 22.652  -78.471 -152.005 1.00 91.97  ? 250 GLN A NE2 1 
ATOM 1718 N N   . LEU A 1 251 ? 20.562  -72.927 -150.178 1.00 72.26  ? 251 LEU A N   1 
ATOM 1719 C CA  . LEU A 1 251 ? 20.653  -71.543 -149.735 1.00 71.30  ? 251 LEU A CA  1 
ATOM 1720 C C   . LEU A 1 251 ? 19.273  -70.992 -149.409 1.00 74.08  ? 251 LEU A C   1 
ATOM 1721 O O   . LEU A 1 251 ? 19.071  -70.360 -148.367 1.00 76.40  ? 251 LEU A O   1 
ATOM 1722 C CB  . LEU A 1 251 ? 21.338  -70.703 -150.810 1.00 70.41  ? 251 LEU A CB  1 
ATOM 1723 C CG  . LEU A 1 251 ? 22.831  -70.983 -150.955 1.00 71.84  ? 251 LEU A CG  1 
ATOM 1724 C CD1 . LEU A 1 251 ? 23.498  -69.930 -151.813 1.00 68.09  ? 251 LEU A CD1 1 
ATOM 1725 C CD2 . LEU A 1 251 ? 23.478  -71.052 -149.589 1.00 73.84  ? 251 LEU A CD2 1 
ATOM 1726 N N   . ALA A 1 252 ? 18.302  -71.236 -150.288 1.00 83.81  ? 252 ALA A N   1 
ATOM 1727 C CA  . ALA A 1 252 ? 16.927  -70.851 -149.999 1.00 82.54  ? 252 ALA A CA  1 
ATOM 1728 C C   . ALA A 1 252 ? 16.387  -71.639 -148.814 1.00 87.53  ? 252 ALA A C   1 
ATOM 1729 O O   . ALA A 1 252 ? 15.683  -71.098 -147.955 1.00 93.06  ? 252 ALA A O   1 
ATOM 1730 C CB  . ALA A 1 252 ? 16.055  -71.064 -151.234 1.00 82.20  ? 252 ALA A CB  1 
ATOM 1731 N N   . LYS A 1 253 ? 16.714  -72.932 -148.758 1.00 89.30  ? 253 LYS A N   1 
ATOM 1732 C CA  . LYS A 1 253 ? 16.242  -73.776 -147.665 1.00 86.30  ? 253 LYS A CA  1 
ATOM 1733 C C   . LYS A 1 253 ? 16.793  -73.309 -146.327 1.00 86.99  ? 253 LYS A C   1 
ATOM 1734 O O   . LYS A 1 253 ? 16.077  -73.299 -145.321 1.00 91.99  ? 253 LYS A O   1 
ATOM 1735 C CB  . LYS A 1 253 ? 16.633  -75.229 -147.921 1.00 86.06  ? 253 LYS A CB  1 
ATOM 1736 C CG  . LYS A 1 253 ? 15.681  -75.969 -148.831 1.00 88.00  ? 253 LYS A CG  1 
ATOM 1737 C CD  . LYS A 1 253 ? 15.906  -77.465 -148.754 1.00 85.96  ? 253 LYS A CD  1 
ATOM 1738 C CE  . LYS A 1 253 ? 16.049  -78.055 -150.139 1.00 84.53  ? 253 LYS A CE  1 
ATOM 1739 N NZ  . LYS A 1 253 ? 16.414  -79.491 -150.088 1.00 89.63  ? 253 LYS A NZ  1 
ATOM 1740 N N   . SER A 1 254 ? 18.067  -72.923 -146.293 1.00 76.27  ? 254 SER A N   1 
ATOM 1741 C CA  . SER A 1 254 ? 18.682  -72.471 -145.055 1.00 77.60  ? 254 SER A CA  1 
ATOM 1742 C C   . SER A 1 254 ? 18.311  -71.042 -144.693 1.00 75.51  ? 254 SER A C   1 
ATOM 1743 O O   . SER A 1 254 ? 18.597  -70.616 -143.571 1.00 76.95  ? 254 SER A O   1 
ATOM 1744 C CB  . SER A 1 254 ? 20.203  -72.590 -145.148 1.00 77.83  ? 254 SER A CB  1 
ATOM 1745 O OG  . SER A 1 254 ? 20.599  -73.943 -145.264 1.00 78.70  ? 254 SER A OG  1 
ATOM 1746 N N   . LYS A 1 255 ? 17.686  -70.298 -145.608 1.00 72.64  ? 255 LYS A N   1 
ATOM 1747 C CA  . LYS A 1 255 ? 17.276  -68.915 -145.372 1.00 76.99  ? 255 LYS A CA  1 
ATOM 1748 C C   . LYS A 1 255 ? 18.475  -68.036 -145.009 1.00 81.22  ? 255 LYS A C   1 
ATOM 1749 O O   . LYS A 1 255 ? 18.555  -67.459 -143.925 1.00 82.95  ? 255 LYS A O   1 
ATOM 1750 C CB  . LYS A 1 255 ? 16.199  -68.840 -144.286 1.00 77.42  ? 255 LYS A CB  1 
ATOM 1751 C CG  . LYS A 1 255 ? 15.115  -69.885 -144.407 1.00 78.75  ? 255 LYS A CG  1 
ATOM 1752 C CD  . LYS A 1 255 ? 13.977  -69.401 -145.274 1.00 83.46  ? 255 LYS A CD  1 
ATOM 1753 C CE  . LYS A 1 255 ? 12.700  -70.144 -144.941 1.00 84.62  ? 255 LYS A CE  1 
ATOM 1754 N NZ  . LYS A 1 255 ? 12.529  -70.284 -143.470 1.00 83.27  ? 255 LYS A NZ  1 
ATOM 1755 N N   . TYR A 1 256 ? 19.416  -67.940 -145.946 1.00 83.78  ? 256 TYR A N   1 
ATOM 1756 C CA  . TYR A 1 256 ? 20.608  -67.115 -145.759 1.00 82.17  ? 256 TYR A CA  1 
ATOM 1757 C C   . TYR A 1 256 ? 20.363  -65.754 -146.391 1.00 84.95  ? 256 TYR A C   1 
ATOM 1758 O O   . TYR A 1 256 ? 20.709  -65.512 -147.546 1.00 87.13  ? 256 TYR A O   1 
ATOM 1759 C CB  . TYR A 1 256 ? 21.836  -67.786 -146.357 1.00 77.97  ? 256 TYR A CB  1 
ATOM 1760 C CG  . TYR A 1 256 ? 22.349  -68.947 -145.551 1.00 77.97  ? 256 TYR A CG  1 
ATOM 1761 C CD1 . TYR A 1 256 ? 22.275  -68.935 -144.169 1.00 82.94  ? 256 TYR A CD1 1 
ATOM 1762 C CD2 . TYR A 1 256 ? 22.936  -70.040 -146.166 1.00 78.05  ? 256 TYR A CD2 1 
ATOM 1763 C CE1 . TYR A 1 256 ? 22.747  -69.987 -143.423 1.00 83.87  ? 256 TYR A CE1 1 
ATOM 1764 C CE2 . TYR A 1 256 ? 23.415  -71.095 -145.427 1.00 82.25  ? 256 TYR A CE2 1 
ATOM 1765 C CZ  . TYR A 1 256 ? 23.316  -71.063 -144.055 1.00 87.28  ? 256 TYR A CZ  1 
ATOM 1766 O OH  . TYR A 1 256 ? 23.792  -72.112 -143.306 1.00 95.48  ? 256 TYR A OH  1 
ATOM 1767 N N   . THR A 1 257 ? 19.794  -64.836 -145.608 1.00 73.29  ? 257 THR A N   1 
ATOM 1768 C CA  . THR A 1 257 ? 19.443  -63.521 -146.132 1.00 69.47  ? 257 THR A CA  1 
ATOM 1769 C C   . THR A 1 257 ? 20.650  -62.719 -146.585 1.00 66.61  ? 257 THR A C   1 
ATOM 1770 O O   . THR A 1 257 ? 20.474  -61.735 -147.309 1.00 70.65  ? 257 THR A O   1 
ATOM 1771 C CB  . THR A 1 257 ? 18.685  -62.713 -145.083 1.00 63.24  ? 257 THR A CB  1 
ATOM 1772 O OG1 . THR A 1 257 ? 19.495  -62.577 -143.911 1.00 68.33  ? 257 THR A OG1 1 
ATOM 1773 C CG2 . THR A 1 257 ? 17.392  -63.408 -144.713 1.00 64.65  ? 257 THR A CG2 1 
ATOM 1774 N N   . ARG A 1 258 ? 21.862  -63.106 -146.189 1.00 55.97  ? 258 ARG A N   1 
ATOM 1775 C CA  . ARG A 1 258 ? 23.060  -62.334 -146.485 1.00 58.98  ? 258 ARG A CA  1 
ATOM 1776 C C   . ARG A 1 258 ? 23.870  -62.913 -147.636 1.00 60.44  ? 258 ARG A C   1 
ATOM 1777 O O   . ARG A 1 258 ? 25.065  -62.626 -147.748 1.00 64.33  ? 258 ARG A O   1 
ATOM 1778 C CB  . ARG A 1 258 ? 23.934  -62.214 -145.240 1.00 60.13  ? 258 ARG A CB  1 
ATOM 1779 C CG  . ARG A 1 258 ? 23.216  -61.641 -144.041 1.00 60.97  ? 258 ARG A CG  1 
ATOM 1780 C CD  . ARG A 1 258 ? 23.985  -60.476 -143.466 1.00 60.19  ? 258 ARG A CD  1 
ATOM 1781 N NE  . ARG A 1 258 ? 23.102  -59.474 -142.887 1.00 63.12  ? 258 ARG A NE  1 
ATOM 1782 C CZ  . ARG A 1 258 ? 23.423  -58.198 -142.740 1.00 66.92  ? 258 ARG A CZ  1 
ATOM 1783 N NH1 . ARG A 1 258 ? 24.604  -57.737 -143.113 1.00 63.23  ? 258 ARG A NH1 1 
ATOM 1784 N NH2 . ARG A 1 258 ? 22.537  -57.362 -142.207 1.00 71.37  ? 258 ARG A NH2 1 
ATOM 1785 N N   . THR A 1 259 ? 23.258  -63.717 -148.495 1.00 61.44  ? 259 THR A N   1 
ATOM 1786 C CA  . THR A 1 259 ? 23.930  -64.194 -149.693 1.00 62.56  ? 259 THR A CA  1 
ATOM 1787 C C   . THR A 1 259 ? 23.051  -63.934 -150.903 1.00 69.60  ? 259 THR A C   1 
ATOM 1788 O O   . THR A 1 259 ? 21.822  -64.015 -150.821 1.00 73.73  ? 259 THR A O   1 
ATOM 1789 C CB  . THR A 1 259 ? 24.270  -65.682 -149.607 1.00 66.44  ? 259 THR A CB  1 
ATOM 1790 O OG1 . THR A 1 259 ? 24.955  -66.079 -150.799 1.00 69.25  ? 259 THR A OG1 1 
ATOM 1791 C CG2 . THR A 1 259 ? 23.017  -66.510 -149.467 1.00 72.04  ? 259 THR A CG2 1 
ATOM 1792 N N   . VAL A 1 260 ? 23.684  -63.606 -152.022 1.00 69.99  ? 260 VAL A N   1 
ATOM 1793 C CA  . VAL A 1 260 ? 22.990  -63.297 -153.264 1.00 63.60  ? 260 VAL A CA  1 
ATOM 1794 C C   . VAL A 1 260 ? 23.511  -64.243 -154.332 1.00 70.15  ? 260 VAL A C   1 
ATOM 1795 O O   . VAL A 1 260 ? 24.715  -64.261 -154.616 1.00 79.14  ? 260 VAL A O   1 
ATOM 1796 C CB  . VAL A 1 260 ? 23.196  -61.835 -153.680 1.00 63.07  ? 260 VAL A CB  1 
ATOM 1797 C CG1 . VAL A 1 260 ? 22.412  -61.530 -154.930 1.00 66.69  ? 260 VAL A CG1 1 
ATOM 1798 C CG2 . VAL A 1 260 ? 22.781  -60.910 -152.561 1.00 69.27  ? 260 VAL A CG2 1 
ATOM 1799 N N   . CYS A 1 261 ? 22.613  -65.019 -154.927 1.00 66.82  ? 261 CYS A N   1 
ATOM 1800 C CA  . CYS A 1 261 ? 22.975  -66.002 -155.938 1.00 68.36  ? 261 CYS A CA  1 
ATOM 1801 C C   . CYS A 1 261 ? 22.399  -65.570 -157.276 1.00 73.41  ? 261 CYS A C   1 
ATOM 1802 O O   . CYS A 1 261 ? 21.194  -65.325 -157.385 1.00 85.28  ? 261 CYS A O   1 
ATOM 1803 C CB  . CYS A 1 261 ? 22.468  -67.389 -155.560 1.00 71.95  ? 261 CYS A CB  1 
ATOM 1804 S SG  . CYS A 1 261 ? 23.070  -68.694 -156.642 1.00 96.44  ? 261 CYS A SG  1 
ATOM 1805 N N   . LEU A 1 262 ? 23.255  -65.481 -158.285 1.00 62.36  ? 262 LEU A N   1 
ATOM 1806 C CA  . LEU A 1 262 ? 22.863  -65.063 -159.624 1.00 61.99  ? 262 LEU A CA  1 
ATOM 1807 C C   . LEU A 1 262 ? 23.183  -66.206 -160.575 1.00 66.09  ? 262 LEU A C   1 
ATOM 1808 O O   . LEU A 1 262 ? 24.355  -66.499 -160.825 1.00 74.65  ? 262 LEU A O   1 
ATOM 1809 C CB  . LEU A 1 262 ? 23.588  -63.777 -160.019 1.00 58.78  ? 262 LEU A CB  1 
ATOM 1810 C CG  . LEU A 1 262 ? 23.341  -63.089 -161.365 1.00 55.41  ? 262 LEU A CG  1 
ATOM 1811 C CD1 . LEU A 1 262 ? 23.854  -61.673 -161.288 1.00 61.83  ? 262 LEU A CD1 1 
ATOM 1812 C CD2 . LEU A 1 262 ? 24.017  -63.790 -162.518 1.00 62.15  ? 262 LEU A CD2 1 
ATOM 1813 N N   . TRP A 1 263 ? 22.149  -66.847 -161.106 1.00 73.75  ? 263 TRP A N   1 
ATOM 1814 C CA  . TRP A 1 263 ? 22.347  -67.951 -162.035 1.00 74.08  ? 263 TRP A CA  1 
ATOM 1815 C C   . TRP A 1 263 ? 22.704  -67.405 -163.409 1.00 79.96  ? 263 TRP A C   1 
ATOM 1816 O O   . TRP A 1 263 ? 21.866  -66.796 -164.079 1.00 86.35  ? 263 TRP A O   1 
ATOM 1817 C CB  . TRP A 1 263 ? 21.094  -68.813 -162.105 1.00 71.39  ? 263 TRP A CB  1 
ATOM 1818 C CG  . TRP A 1 263 ? 21.337  -70.149 -162.706 1.00 71.82  ? 263 TRP A CG  1 
ATOM 1819 C CD1 . TRP A 1 263 ? 21.482  -71.325 -162.044 1.00 79.25  ? 263 TRP A CD1 1 
ATOM 1820 C CD2 . TRP A 1 263 ? 21.470  -70.452 -164.097 1.00 68.75  ? 263 TRP A CD2 1 
ATOM 1821 N NE1 . TRP A 1 263 ? 21.695  -72.344 -162.933 1.00 80.93  ? 263 TRP A NE1 1 
ATOM 1822 C CE2 . TRP A 1 263 ? 21.691  -71.833 -164.202 1.00 75.60  ? 263 TRP A CE2 1 
ATOM 1823 C CE3 . TRP A 1 263 ? 21.420  -69.690 -165.265 1.00 73.32  ? 263 TRP A CE3 1 
ATOM 1824 C CZ2 . TRP A 1 263 ? 21.865  -72.468 -165.423 1.00 81.27  ? 263 TRP A CZ2 1 
ATOM 1825 C CZ3 . TRP A 1 263 ? 21.594  -70.322 -166.474 1.00 75.96  ? 263 TRP A CZ3 1 
ATOM 1826 C CH2 . TRP A 1 263 ? 21.812  -71.696 -166.546 1.00 79.29  ? 263 TRP A CH2 1 
ATOM 1827 N N   . HIS A 1 264 ? 23.940  -67.627 -163.840 1.00 75.67  ? 264 HIS A N   1 
ATOM 1828 C CA  . HIS A 1 264 ? 24.380  -67.249 -165.172 1.00 74.15  ? 264 HIS A CA  1 
ATOM 1829 C C   . HIS A 1 264 ? 25.126  -68.414 -165.800 1.00 73.57  ? 264 HIS A C   1 
ATOM 1830 O O   . HIS A 1 264 ? 25.839  -69.151 -165.118 1.00 75.47  ? 264 HIS A O   1 
ATOM 1831 C CB  . HIS A 1 264 ? 25.273  -66.010 -165.138 1.00 69.96  ? 264 HIS A CB  1 
ATOM 1832 C CG  . HIS A 1 264 ? 25.267  -65.227 -166.411 1.00 75.68  ? 264 HIS A CG  1 
ATOM 1833 N ND1 . HIS A 1 264 ? 26.244  -65.363 -167.372 1.00 78.42  ? 264 HIS A ND1 1 
ATOM 1834 C CD2 . HIS A 1 264 ? 24.399  -64.305 -166.887 1.00 76.71  ? 264 HIS A CD2 1 
ATOM 1835 C CE1 . HIS A 1 264 ? 25.982  -64.553 -168.381 1.00 77.09  ? 264 HIS A CE1 1 
ATOM 1836 N NE2 . HIS A 1 264 ? 24.868  -63.900 -168.112 1.00 75.80  ? 264 HIS A NE2 1 
ATOM 1837 N N   . HIS A 1 265 ? 24.958  -68.573 -167.113 1.00 80.96  ? 265 HIS A N   1 
ATOM 1838 C CA  . HIS A 1 265 ? 25.575  -69.707 -167.789 1.00 76.36  ? 265 HIS A CA  1 
ATOM 1839 C C   . HIS A 1 265 ? 27.090  -69.586 -167.826 1.00 83.65  ? 265 HIS A C   1 
ATOM 1840 O O   . HIS A 1 265 ? 27.784  -70.592 -167.995 1.00 89.46  ? 265 HIS A O   1 
ATOM 1841 C CB  . HIS A 1 265 ? 25.024  -69.847 -169.204 1.00 78.53  ? 265 HIS A CB  1 
ATOM 1842 C CG  . HIS A 1 265 ? 25.442  -68.749 -170.129 1.00 83.94  ? 265 HIS A CG  1 
ATOM 1843 N ND1 . HIS A 1 265 ? 25.086  -67.434 -169.932 1.00 88.71  ? 265 HIS A ND1 1 
ATOM 1844 C CD2 . HIS A 1 265 ? 26.179  -68.772 -171.264 1.00 84.55  ? 265 HIS A CD2 1 
ATOM 1845 C CE1 . HIS A 1 265 ? 25.588  -66.693 -170.904 1.00 86.00  ? 265 HIS A CE1 1 
ATOM 1846 N NE2 . HIS A 1 265 ? 26.255  -67.482 -171.726 1.00 85.94  ? 265 HIS A NE2 1 
ATOM 1847 N N   . THR A 1 266 ? 27.620  -68.377 -167.673 1.00 78.27  ? 266 THR A N   1 
ATOM 1848 C CA  . THR A 1 266 ? 29.065  -68.171 -167.662 1.00 71.86  ? 266 THR A CA  1 
ATOM 1849 C C   . THR A 1 266 ? 29.625  -68.211 -166.247 1.00 77.76  ? 266 THR A C   1 
ATOM 1850 O O   . THR A 1 266 ? 30.335  -67.308 -165.817 1.00 89.69  ? 266 THR A O   1 
ATOM 1851 C CB  . THR A 1 266 ? 29.412  -66.852 -168.337 1.00 76.11  ? 266 THR A CB  1 
ATOM 1852 O OG1 . THR A 1 266 ? 28.895  -65.769 -167.556 1.00 85.16  ? 266 THR A OG1 1 
ATOM 1853 C CG2 . THR A 1 266 ? 28.809  -66.795 -169.720 1.00 78.76  ? 266 THR A CG2 1 
ATOM 1854 N N   . ALA A 1 267 ? 29.305  -69.267 -165.506 1.00 88.07  ? 267 ALA A N   1 
ATOM 1855 C CA  . ALA A 1 267 ? 29.928  -69.479 -164.208 1.00 88.34  ? 267 ALA A CA  1 
ATOM 1856 C C   . ALA A 1 267 ? 31.270  -70.166 -164.412 1.00 96.60  ? 267 ALA A C   1 
ATOM 1857 O O   . ALA A 1 267 ? 31.762  -70.233 -165.543 1.00 101.63 ? 267 ALA A O   1 
ATOM 1858 C CB  . ALA A 1 267 ? 29.026  -70.298 -163.290 1.00 88.15  ? 267 ALA A CB  1 
ATOM 1859 N N   . GLU A 1 268 ? 31.853  -70.694 -163.333 1.00 108.77 ? 268 GLU A N   1 
ATOM 1860 C CA  . GLU A 1 268 ? 33.195  -71.279 -163.315 1.00 107.44 ? 268 GLU A CA  1 
ATOM 1861 C C   . GLU A 1 268 ? 34.173  -70.520 -164.207 1.00 108.49 ? 268 GLU A C   1 
ATOM 1862 O O   . GLU A 1 268 ? 35.065  -69.831 -163.704 1.00 107.88 ? 268 GLU A O   1 
ATOM 1863 C CB  . GLU A 1 268 ? 33.173  -72.767 -163.701 1.00 102.87 ? 268 GLU A CB  1 
ATOM 1864 C CG  . GLU A 1 268 ? 32.257  -73.179 -164.844 1.00 104.53 ? 268 GLU A CG  1 
ATOM 1865 C CD  . GLU A 1 268 ? 30.900  -73.638 -164.362 1.00 105.37 ? 268 GLU A CD  1 
ATOM 1866 O OE1 . GLU A 1 268 ? 30.464  -73.176 -163.288 1.00 102.79 ? 268 GLU A OE1 1 
ATOM 1867 O OE2 . GLU A 1 268 ? 30.265  -74.458 -165.058 1.00 111.13 ? 268 GLU A OE2 1 
ATOM 1868 N N   . PHE A 1 269 ? 34.025  -70.653 -165.524 1.00 99.03  ? 269 PHE A N   1 
ATOM 1869 C CA  . PHE A 1 269 ? 34.903  -69.985 -166.476 1.00 95.25  ? 269 PHE A CA  1 
ATOM 1870 C C   . PHE A 1 269 ? 34.976  -68.487 -166.209 1.00 98.57  ? 269 PHE A C   1 
ATOM 1871 O O   . PHE A 1 269 ? 36.069  -67.919 -166.140 1.00 101.47 ? 269 PHE A O   1 
ATOM 1872 C CB  . PHE A 1 269 ? 34.431  -70.243 -167.907 1.00 85.86  ? 269 PHE A CB  1 
ATOM 1873 N N   . ASP A 1 270 ? 33.827  -67.842 -166.051 1.00 93.69  ? 270 ASP A N   1 
ATOM 1874 C CA  . ASP A 1 270 ? 33.775  -66.412 -165.797 1.00 93.09  ? 270 ASP A CA  1 
ATOM 1875 C C   . ASP A 1 270 ? 33.070  -66.134 -164.475 1.00 98.76  ? 270 ASP A C   1 
ATOM 1876 O O   . ASP A 1 270 ? 32.487  -67.020 -163.847 1.00 96.26  ? 270 ASP A O   1 
ATOM 1877 C CB  . ASP A 1 270 ? 33.086  -65.689 -166.952 1.00 94.52  ? 270 ASP A CB  1 
ATOM 1878 C CG  . ASP A 1 270 ? 33.472  -64.230 -167.030 1.00 101.45 ? 270 ASP A CG  1 
ATOM 1879 O OD1 . ASP A 1 270 ? 34.077  -63.725 -166.063 1.00 99.27  ? 270 ASP A OD1 1 
ATOM 1880 O OD2 . ASP A 1 270 ? 33.165  -63.585 -168.053 1.00 108.31 ? 270 ASP A OD2 1 
ATOM 1881 N N   . TYR A 1 271 ? 33.128  -64.873 -164.047 1.00 94.79  ? 271 TYR A N   1 
ATOM 1882 C CA  . TYR A 1 271 ? 32.551  -64.431 -162.779 1.00 85.71  ? 271 TYR A CA  1 
ATOM 1883 C C   . TYR A 1 271 ? 31.665  -63.228 -163.054 1.00 87.48  ? 271 TYR A C   1 
ATOM 1884 O O   . TYR A 1 271 ? 32.122  -62.078 -163.006 1.00 91.08  ? 271 TYR A O   1 
ATOM 1885 C CB  . TYR A 1 271 ? 33.638  -64.105 -161.759 1.00 79.49  ? 271 TYR A CB  1 
ATOM 1886 C CG  . TYR A 1 271 ? 34.476  -65.305 -161.405 1.00 87.61  ? 271 TYR A CG  1 
ATOM 1887 C CD1 . TYR A 1 271 ? 35.461  -65.766 -162.264 1.00 93.24  ? 271 TYR A CD1 1 
ATOM 1888 C CD2 . TYR A 1 271 ? 34.262  -65.995 -160.228 1.00 89.74  ? 271 TYR A CD2 1 
ATOM 1889 C CE1 . TYR A 1 271 ? 36.214  -66.871 -161.952 1.00 91.74  ? 271 TYR A CE1 1 
ATOM 1890 C CE2 . TYR A 1 271 ? 35.013  -67.102 -159.907 1.00 91.74  ? 271 TYR A CE2 1 
ATOM 1891 C CZ  . TYR A 1 271 ? 35.987  -67.533 -160.772 1.00 90.33  ? 271 TYR A CZ  1 
ATOM 1892 O OH  . TYR A 1 271 ? 36.735  -68.636 -160.458 1.00 91.77  ? 271 TYR A OH  1 
ATOM 1893 N N   . PRO A 1 272 ? 30.384  -63.452 -163.355 1.00 77.46  ? 272 PRO A N   1 
ATOM 1894 C CA  . PRO A 1 272 ? 29.507  -62.327 -163.697 1.00 77.62  ? 272 PRO A CA  1 
ATOM 1895 C C   . PRO A 1 272 ? 28.974  -61.577 -162.495 1.00 82.73  ? 272 PRO A C   1 
ATOM 1896 O O   . PRO A 1 272 ? 28.486  -60.454 -162.664 1.00 86.42  ? 272 PRO A O   1 
ATOM 1897 C CB  . PRO A 1 272 ? 28.363  -62.993 -164.474 1.00 76.54  ? 272 PRO A CB  1 
ATOM 1898 C CG  . PRO A 1 272 ? 28.543  -64.482 -164.301 1.00 75.87  ? 272 PRO A CG  1 
ATOM 1899 C CD  . PRO A 1 272 ? 29.659  -64.728 -163.343 1.00 78.47  ? 272 PRO A CD  1 
ATOM 1900 N N   . GLU A 1 273 ? 29.048  -62.149 -161.292 1.00 83.41  ? 273 GLU A N   1 
ATOM 1901 C CA  . GLU A 1 273 ? 28.481  -61.481 -160.129 1.00 77.30  ? 273 GLU A CA  1 
ATOM 1902 C C   . GLU A 1 273 ? 29.229  -60.207 -159.776 1.00 78.44  ? 273 GLU A C   1 
ATOM 1903 O O   . GLU A 1 273 ? 28.680  -59.358 -159.066 1.00 87.38  ? 273 GLU A O   1 
ATOM 1904 C CB  . GLU A 1 273 ? 28.474  -62.421 -158.929 1.00 72.38  ? 273 GLU A CB  1 
ATOM 1905 C CG  . GLU A 1 273 ? 29.824  -62.591 -158.267 1.00 77.46  ? 273 GLU A CG  1 
ATOM 1906 C CD  . GLU A 1 273 ? 30.663  -63.673 -158.909 1.00 93.14  ? 273 GLU A CD  1 
ATOM 1907 O OE1 . GLU A 1 273 ? 30.677  -63.763 -160.154 1.00 94.94  ? 273 GLU A OE1 1 
ATOM 1908 O OE2 . GLU A 1 273 ? 31.309  -64.440 -158.166 1.00 95.92  ? 273 GLU A OE2 1 
ATOM 1909 N N   . MET A 1 274 ? 30.463  -60.049 -160.250 1.00 73.17  ? 274 MET A N   1 
ATOM 1910 C CA  . MET A 1 274 ? 31.199  -58.826 -159.964 1.00 79.33  ? 274 MET A CA  1 
ATOM 1911 C C   . MET A 1 274 ? 30.545  -57.628 -160.638 1.00 79.68  ? 274 MET A C   1 
ATOM 1912 O O   . MET A 1 274 ? 30.498  -56.534 -160.066 1.00 83.77  ? 274 MET A O   1 
ATOM 1913 C CB  . MET A 1 274 ? 32.653  -58.971 -160.404 1.00 80.30  ? 274 MET A CB  1 
ATOM 1914 C CG  . MET A 1 274 ? 33.440  -59.964 -159.571 1.00 81.89  ? 274 MET A CG  1 
ATOM 1915 S SD  . MET A 1 274 ? 33.156  -59.789 -157.804 1.00 83.83  ? 274 MET A SD  1 
ATOM 1916 C CE  . MET A 1 274 ? 34.477  -58.675 -157.365 1.00 75.54  ? 274 MET A CE  1 
ATOM 1917 N N   . ALA A 1 275 ? 30.031  -57.814 -161.854 1.00 71.17  ? 275 ALA A N   1 
ATOM 1918 C CA  . ALA A 1 275 ? 29.290  -56.741 -162.505 1.00 72.53  ? 275 ALA A CA  1 
ATOM 1919 C C   . ALA A 1 275 ? 28.040  -56.388 -161.714 1.00 72.90  ? 275 ALA A C   1 
ATOM 1920 O O   . ALA A 1 275 ? 27.698  -55.208 -161.563 1.00 76.70  ? 275 ALA A O   1 
ATOM 1921 C CB  . ALA A 1 275 ? 28.927  -57.141 -163.932 1.00 71.97  ? 275 ALA A CB  1 
ATOM 1922 N N   . TYR A 1 276 ? 27.343  -57.398 -161.197 1.00 66.11  ? 276 TYR A N   1 
ATOM 1923 C CA  . TYR A 1 276 ? 26.172  -57.125 -160.379 1.00 60.03  ? 276 TYR A CA  1 
ATOM 1924 C C   . TYR A 1 276 ? 26.547  -56.363 -159.119 1.00 65.20  ? 276 TYR A C   1 
ATOM 1925 O O   . TYR A 1 276 ? 25.788  -55.500 -158.670 1.00 74.46  ? 276 TYR A O   1 
ATOM 1926 C CB  . TYR A 1 276 ? 25.461  -58.430 -160.033 1.00 60.14  ? 276 TYR A CB  1 
ATOM 1927 C CG  . TYR A 1 276 ? 24.049  -58.237 -159.546 1.00 60.76  ? 276 TYR A CG  1 
ATOM 1928 C CD1 . TYR A 1 276 ? 23.174  -57.413 -160.230 1.00 67.68  ? 276 TYR A CD1 1 
ATOM 1929 C CD2 . TYR A 1 276 ? 23.583  -58.897 -158.425 1.00 65.58  ? 276 TYR A CD2 1 
ATOM 1930 C CE1 . TYR A 1 276 ? 21.884  -57.234 -159.797 1.00 70.54  ? 276 TYR A CE1 1 
ATOM 1931 C CE2 . TYR A 1 276 ? 22.293  -58.728 -157.988 1.00 68.20  ? 276 TYR A CE2 1 
ATOM 1932 C CZ  . TYR A 1 276 ? 21.449  -57.896 -158.679 1.00 70.33  ? 276 TYR A CZ  1 
ATOM 1933 O OH  . TYR A 1 276 ? 20.158  -57.720 -158.247 1.00 78.21  ? 276 TYR A OH  1 
ATOM 1934 N N   . ILE A 1 277 ? 27.711  -56.661 -158.538 1.00 63.54  ? 277 ILE A N   1 
ATOM 1935 C CA  . ILE A 1 277 ? 28.186  -55.874 -157.403 1.00 63.95  ? 277 ILE A CA  1 
ATOM 1936 C C   . ILE A 1 277 ? 28.427  -54.435 -157.823 1.00 63.12  ? 277 ILE A C   1 
ATOM 1937 O O   . ILE A 1 277 ? 28.007  -53.494 -157.142 1.00 72.81  ? 277 ILE A O   1 
ATOM 1938 C CB  . ILE A 1 277 ? 29.459  -56.495 -156.806 1.00 67.44  ? 277 ILE A CB  1 
ATOM 1939 C CG1 . ILE A 1 277 ? 29.164  -57.869 -156.215 1.00 70.94  ? 277 ILE A CG1 1 
ATOM 1940 C CG2 . ILE A 1 277 ? 30.043  -55.580 -155.753 1.00 58.09  ? 277 ILE A CG2 1 
ATOM 1941 C CD1 . ILE A 1 277 ? 30.357  -58.500 -155.549 1.00 65.89  ? 277 ILE A CD1 1 
ATOM 1942 N N   . ALA A 1 278 ? 29.100  -54.243 -158.955 1.00 57.62  ? 278 ALA A N   1 
ATOM 1943 C CA  . ALA A 1 278 ? 29.426  -52.895 -159.403 1.00 62.26  ? 278 ALA A CA  1 
ATOM 1944 C C   . ALA A 1 278 ? 28.191  -52.102 -159.795 1.00 62.79  ? 278 ALA A C   1 
ATOM 1945 O O   . ALA A 1 278 ? 28.263  -50.873 -159.889 1.00 62.66  ? 278 ALA A O   1 
ATOM 1946 C CB  . ALA A 1 278 ? 30.396  -52.953 -160.578 1.00 68.21  ? 278 ALA A CB  1 
ATOM 1947 N N   . TYR A 1 279 ? 27.068  -52.775 -160.044 1.00 66.11  ? 279 TYR A N   1 
ATOM 1948 C CA  . TYR A 1 279 ? 25.848  -52.049 -160.381 1.00 63.52  ? 279 TYR A CA  1 
ATOM 1949 C C   . TYR A 1 279 ? 25.415  -51.131 -159.246 1.00 65.48  ? 279 TYR A C   1 
ATOM 1950 O O   . TYR A 1 279 ? 24.983  -50.000 -159.486 1.00 78.43  ? 279 TYR A O   1 
ATOM 1951 C CB  . TYR A 1 279 ? 24.723  -53.020 -160.726 1.00 64.06  ? 279 TYR A CB  1 
ATOM 1952 C CG  . TYR A 1 279 ? 23.383  -52.340 -160.900 1.00 70.86  ? 279 TYR A CG  1 
ATOM 1953 C CD1 . TYR A 1 279 ? 23.050  -51.716 -162.090 1.00 71.98  ? 279 TYR A CD1 1 
ATOM 1954 C CD2 . TYR A 1 279 ? 22.456  -52.318 -159.870 1.00 71.15  ? 279 TYR A CD2 1 
ATOM 1955 C CE1 . TYR A 1 279 ? 21.831  -51.094 -162.249 1.00 74.31  ? 279 TYR A CE1 1 
ATOM 1956 C CE2 . TYR A 1 279 ? 21.238  -51.696 -160.020 1.00 68.29  ? 279 TYR A CE2 1 
ATOM 1957 C CZ  . TYR A 1 279 ? 20.931  -51.088 -161.210 1.00 71.74  ? 279 TYR A CZ  1 
ATOM 1958 O OH  . TYR A 1 279 ? 19.717  -50.469 -161.360 1.00 71.02  ? 279 TYR A OH  1 
ATOM 1959 N N   . GLY A 1 280 ? 25.502  -51.602 -158.007 1.00 53.08  ? 280 GLY A N   1 
ATOM 1960 C CA  . GLY A 1 280 ? 25.022  -50.819 -156.885 1.00 63.55  ? 280 GLY A CA  1 
ATOM 1961 C C   . GLY A 1 280 ? 26.081  -50.410 -155.883 1.00 63.65  ? 280 GLY A C   1 
ATOM 1962 O O   . GLY A 1 280 ? 25.782  -49.713 -154.909 1.00 67.33  ? 280 GLY A O   1 
ATOM 1963 N N   . ALA A 1 281 ? 27.319  -50.844 -156.100 1.00 63.21  ? 281 ALA A N   1 
ATOM 1964 C CA  . ALA A 1 281 ? 28.404  -50.475 -155.194 1.00 58.98  ? 281 ALA A CA  1 
ATOM 1965 C C   . ALA A 1 281 ? 28.638  -48.972 -155.107 1.00 68.40  ? 281 ALA A C   1 
ATOM 1966 O O   . ALA A 1 281 ? 28.787  -48.464 -153.983 1.00 77.09  ? 281 ALA A O   1 
ATOM 1967 C CB  . ALA A 1 281 ? 29.686  -51.204 -155.601 1.00 61.49  ? 281 ALA A CB  1 
ATOM 1968 N N   . PRO A 1 282 ? 28.696  -48.210 -156.201 1.00 65.30  ? 282 PRO A N   1 
ATOM 1969 C CA  . PRO A 1 282 ? 29.030  -46.788 -156.079 1.00 65.33  ? 282 PRO A CA  1 
ATOM 1970 C C   . PRO A 1 282 ? 27.862  -45.892 -155.706 1.00 71.29  ? 282 PRO A C   1 
ATOM 1971 O O   . PRO A 1 282 ? 28.020  -44.668 -155.728 1.00 80.90  ? 282 PRO A O   1 
ATOM 1972 C CB  . PRO A 1 282 ? 29.557  -46.433 -157.477 1.00 64.73  ? 282 PRO A CB  1 
ATOM 1973 C CG  . PRO A 1 282 ? 29.265  -47.601 -158.350 1.00 63.25  ? 282 PRO A CG  1 
ATOM 1974 C CD  . PRO A 1 282 ? 28.445  -48.572 -157.602 1.00 63.39  ? 282 PRO A CD  1 
ATOM 1975 N N   . TYR A 1 283 ? 26.704  -46.444 -155.370 1.00 66.57  ? 283 TYR A N   1 
ATOM 1976 C CA  . TYR A 1 283 ? 25.540  -45.647 -155.027 1.00 65.30  ? 283 TYR A CA  1 
ATOM 1977 C C   . TYR A 1 283 ? 25.206  -45.810 -153.552 1.00 66.42  ? 283 TYR A C   1 
ATOM 1978 O O   . TYR A 1 283 ? 25.394  -46.880 -152.970 1.00 68.23  ? 283 TYR A O   1 
ATOM 1979 C CB  . TYR A 1 283 ? 24.345  -46.037 -155.892 1.00 62.58  ? 283 TYR A CB  1 
ATOM 1980 C CG  . TYR A 1 283 ? 24.538  -45.653 -157.333 1.00 60.91  ? 283 TYR A CG  1 
ATOM 1981 C CD1 . TYR A 1 283 ? 24.451  -44.334 -157.729 1.00 67.74  ? 283 TYR A CD1 1 
ATOM 1982 C CD2 . TYR A 1 283 ? 24.833  -46.605 -158.292 1.00 61.93  ? 283 TYR A CD2 1 
ATOM 1983 C CE1 . TYR A 1 283 ? 24.637  -43.973 -159.038 1.00 73.18  ? 283 TYR A CE1 1 
ATOM 1984 C CE2 . TYR A 1 283 ? 25.019  -46.254 -159.604 1.00 65.32  ? 283 TYR A CE2 1 
ATOM 1985 C CZ  . TYR A 1 283 ? 24.921  -44.935 -159.971 1.00 72.58  ? 283 TYR A CZ  1 
ATOM 1986 O OH  . TYR A 1 283 ? 25.107  -44.566 -161.280 1.00 79.70  ? 283 TYR A OH  1 
ATOM 1987 N N   . ASP A 1 284 ? 24.712  -44.728 -152.957 1.00 71.39  ? 284 ASP A N   1 
ATOM 1988 C CA  . ASP A 1 284 ? 24.450  -44.706 -151.525 1.00 68.81  ? 284 ASP A CA  1 
ATOM 1989 C C   . ASP A 1 284 ? 23.445  -45.781 -151.148 1.00 70.62  ? 284 ASP A C   1 
ATOM 1990 O O   . ASP A 1 284 ? 22.408  -45.934 -151.798 1.00 74.70  ? 284 ASP A O   1 
ATOM 1991 C CB  . ASP A 1 284 ? 23.935  -43.332 -151.113 1.00 70.26  ? 284 ASP A CB  1 
ATOM 1992 C CG  . ASP A 1 284 ? 24.791  -42.205 -151.652 1.00 81.93  ? 284 ASP A CG  1 
ATOM 1993 O OD1 . ASP A 1 284 ? 25.980  -42.446 -151.938 1.00 79.03  ? 284 ASP A OD1 1 
ATOM 1994 O OD2 . ASP A 1 284 ? 24.274  -41.078 -151.792 1.00 90.36  ? 284 ASP A OD2 1 
ATOM 1995 N N   . ALA A 1 285 ? 23.753  -46.521 -150.091 1.00 64.66  ? 285 ALA A N   1 
ATOM 1996 C CA  . ALA A 1 285 ? 22.950  -47.674 -149.720 1.00 63.07  ? 285 ALA A CA  1 
ATOM 1997 C C   . ALA A 1 285 ? 21.557  -47.252 -149.283 1.00 63.17  ? 285 ALA A C   1 
ATOM 1998 O O   . ALA A 1 285 ? 21.387  -46.268 -148.564 1.00 72.14  ? 285 ALA A O   1 
ATOM 1999 C CB  . ALA A 1 285 ? 23.631  -48.450 -148.599 1.00 68.01  ? 285 ALA A CB  1 
ATOM 2000 N N   . GLY A 1 286 ? 20.555  -48.012 -149.719 1.00 58.21  ? 286 GLY A N   1 
ATOM 2001 C CA  . GLY A 1 286 ? 19.180  -47.762 -149.374 1.00 59.42  ? 286 GLY A CA  1 
ATOM 2002 C C   . GLY A 1 286 ? 18.401  -46.971 -150.404 1.00 65.31  ? 286 GLY A C   1 
ATOM 2003 O O   . GLY A 1 286 ? 17.216  -47.240 -150.612 1.00 77.89  ? 286 GLY A O   1 
ATOM 2004 N N   . SER A 1 287 ? 19.039  -46.013 -151.061 1.00 59.04  ? 287 SER A N   1 
ATOM 2005 C CA  . SER A 1 287 ? 18.377  -45.180 -152.053 1.00 59.74  ? 287 SER A CA  1 
ATOM 2006 C C   . SER A 1 287 ? 18.314  -45.833 -153.421 1.00 58.91  ? 287 SER A C   1 
ATOM 2007 O O   . SER A 1 287 ? 17.768  -45.237 -154.352 1.00 66.92  ? 287 SER A O   1 
ATOM 2008 C CB  . SER A 1 287 ? 19.095  -43.838 -152.176 1.00 68.00  ? 287 SER A CB  1 
ATOM 2009 O OG  . SER A 1 287 ? 20.332  -44.002 -152.843 1.00 69.33  ? 287 SER A OG  1 
ATOM 2010 N N   . ILE A 1 288 ? 18.861  -47.031 -153.566 1.00 59.97  ? 288 ILE A N   1 
ATOM 2011 C CA  . ILE A 1 288 ? 18.943  -47.703 -154.849 1.00 55.46  ? 288 ILE A CA  1 
ATOM 2012 C C   . ILE A 1 288 ? 17.990  -48.890 -154.848 1.00 56.31  ? 288 ILE A C   1 
ATOM 2013 O O   . ILE A 1 288 ? 17.617  -49.426 -153.802 1.00 65.94  ? 288 ILE A O   1 
ATOM 2014 C CB  . ILE A 1 288 ? 20.387  -48.145 -155.152 1.00 50.48  ? 288 ILE A CB  1 
ATOM 2015 C CG1 . ILE A 1 288 ? 20.590  -48.344 -156.649 1.00 53.57  ? 288 ILE A CG1 1 
ATOM 2016 C CG2 . ILE A 1 288 ? 20.730  -49.401 -154.392 1.00 52.34  ? 288 ILE A CG2 1 
ATOM 2017 C CD1 . ILE A 1 288 ? 21.972  -48.809 -157.002 1.00 60.71  ? 288 ILE A CD1 1 
ATOM 2018 N N   . ALA A 1 289 ? 17.570  -49.287 -156.043 1.00 57.98  ? 289 ALA A N   1 
ATOM 2019 C CA  . ALA A 1 289 ? 16.732  -50.464 -156.232 1.00 60.10  ? 289 ALA A CA  1 
ATOM 2020 C C   . ALA A 1 289 ? 17.527  -51.473 -157.043 1.00 68.99  ? 289 ALA A C   1 
ATOM 2021 O O   . ALA A 1 289 ? 17.791  -51.252 -158.228 1.00 75.47  ? 289 ALA A O   1 
ATOM 2022 C CB  . ALA A 1 289 ? 15.424  -50.105 -156.930 1.00 66.59  ? 289 ALA A CB  1 
ATOM 2023 N N   . TRP A 1 290 ? 17.901  -52.581 -156.410 1.00 64.19  ? 290 TRP A N   1 
ATOM 2024 C CA  . TRP A 1 290 ? 18.754  -53.576 -157.045 1.00 61.12  ? 290 TRP A CA  1 
ATOM 2025 C C   . TRP A 1 290 ? 18.007  -54.470 -158.019 1.00 59.85  ? 290 TRP A C   1 
ATOM 2026 O O   . TRP A 1 290 ? 18.644  -55.289 -158.688 1.00 63.30  ? 290 TRP A O   1 
ATOM 2027 C CB  . TRP A 1 290 ? 19.427  -54.448 -155.987 1.00 57.62  ? 290 TRP A CB  1 
ATOM 2028 C CG  . TRP A 1 290 ? 20.505  -53.774 -155.213 1.00 56.43  ? 290 TRP A CG  1 
ATOM 2029 C CD1 . TRP A 1 290 ? 20.350  -52.902 -154.184 1.00 62.88  ? 290 TRP A CD1 1 
ATOM 2030 C CD2 . TRP A 1 290 ? 21.911  -53.941 -155.389 1.00 58.02  ? 290 TRP A CD2 1 
ATOM 2031 N NE1 . TRP A 1 290 ? 21.573  -52.504 -153.713 1.00 64.38  ? 290 TRP A NE1 1 
ATOM 2032 C CE2 . TRP A 1 290 ? 22.549  -53.130 -154.439 1.00 62.03  ? 290 TRP A CE2 1 
ATOM 2033 C CE3 . TRP A 1 290 ? 22.694  -54.693 -156.263 1.00 61.85  ? 290 TRP A CE3 1 
ATOM 2034 C CZ2 . TRP A 1 290 ? 23.930  -53.050 -154.338 1.00 57.59  ? 290 TRP A CZ2 1 
ATOM 2035 C CZ3 . TRP A 1 290 ? 24.062  -54.612 -156.160 1.00 65.59  ? 290 TRP A CZ3 1 
ATOM 2036 C CH2 . TRP A 1 290 ? 24.666  -53.800 -155.206 1.00 56.60  ? 290 TRP A CH2 1 
ATOM 2037 N N   . GLY A 1 291 ? 16.690  -54.349 -158.114 1.00 63.73  ? 291 GLY A N   1 
ATOM 2038 C CA  . GLY A 1 291 ? 15.932  -55.293 -158.905 1.00 64.41  ? 291 GLY A CA  1 
ATOM 2039 C C   . GLY A 1 291 ? 16.167  -55.194 -160.395 1.00 64.48  ? 291 GLY A C   1 
ATOM 2040 O O   . GLY A 1 291 ? 16.857  -56.035 -160.972 1.00 75.51  ? 291 GLY A O   1 
ATOM 2041 N N   . ASN A 1 292 ? 15.631  -54.157 -161.028 1.00 67.26  ? 292 ASN A N   1 
ATOM 2042 C CA  . ASN A 1 292 ? 15.658  -54.054 -162.485 1.00 65.84  ? 292 ASN A CA  1 
ATOM 2043 C C   . ASN A 1 292 ? 16.962  -53.391 -162.920 1.00 69.29  ? 292 ASN A C   1 
ATOM 2044 O O   . ASN A 1 292 ? 17.030  -52.201 -163.224 1.00 78.81  ? 292 ASN A O   1 
ATOM 2045 C CB  . ASN A 1 292 ? 14.440  -53.286 -162.978 1.00 68.10  ? 292 ASN A CB  1 
ATOM 2046 C CG  . ASN A 1 292 ? 13.178  -54.104 -162.909 1.00 70.13  ? 292 ASN A CG  1 
ATOM 2047 O OD1 . ASN A 1 292 ? 13.223  -55.322 -162.755 1.00 69.68  ? 292 ASN A OD1 1 
ATOM 2048 N ND2 . ASN A 1 292 ? 12.037  -53.440 -163.008 1.00 73.03  ? 292 ASN A ND2 1 
ATOM 2049 N N   . ALA A 1 293 ? 18.007  -54.203 -162.949 1.00 63.50  ? 293 ALA A N   1 
ATOM 2050 C CA  . ALA A 1 293 ? 19.352  -53.726 -163.219 1.00 62.01  ? 293 ALA A CA  1 
ATOM 2051 C C   . ALA A 1 293 ? 19.776  -54.097 -164.630 1.00 65.94  ? 293 ALA A C   1 
ATOM 2052 O O   . ALA A 1 293 ? 19.600  -55.238 -165.063 1.00 71.69  ? 293 ALA A O   1 
ATOM 2053 C CB  . ALA A 1 293 ? 20.345  -54.306 -162.214 1.00 65.12  ? 293 ALA A CB  1 
ATOM 2054 N N   . GLN A 1 294 ? 20.334  -53.127 -165.340 1.00 78.79  ? 294 GLN A N   1 
ATOM 2055 C CA  . GLN A 1 294 ? 20.956  -53.364 -166.633 1.00 81.55  ? 294 GLN A CA  1 
ATOM 2056 C C   . GLN A 1 294 ? 22.465  -53.367 -166.458 1.00 86.29  ? 294 GLN A C   1 
ATOM 2057 O O   . GLN A 1 294 ? 23.035  -52.412 -165.920 1.00 92.77  ? 294 GLN A O   1 
ATOM 2058 C CB  . GLN A 1 294 ? 20.556  -52.297 -167.648 1.00 81.73  ? 294 GLN A CB  1 
ATOM 2059 C CG  . GLN A 1 294 ? 19.107  -52.330 -168.042 1.00 89.18  ? 294 GLN A CG  1 
ATOM 2060 C CD  . GLN A 1 294 ? 18.828  -51.454 -169.234 1.00 94.01  ? 294 GLN A CD  1 
ATOM 2061 O OE1 . GLN A 1 294 ? 19.729  -50.805 -169.760 1.00 92.57  ? 294 GLN A OE1 1 
ATOM 2062 N NE2 . GLN A 1 294 ? 17.576  -51.425 -169.667 1.00 93.97  ? 294 GLN A NE2 1 
ATOM 2063 N N   . LEU A 1 295 ? 23.108  -54.436 -166.907 1.00 69.29  ? 295 LEU A N   1 
ATOM 2064 C CA  . LEU A 1 295 ? 24.551  -54.576 -166.818 1.00 68.71  ? 295 LEU A CA  1 
ATOM 2065 C C   . LEU A 1 295 ? 25.144  -54.482 -168.214 1.00 76.71  ? 295 LEU A C   1 
ATOM 2066 O O   . LEU A 1 295 ? 24.651  -55.125 -169.146 1.00 86.21  ? 295 LEU A O   1 
ATOM 2067 C CB  . LEU A 1 295 ? 24.929  -55.901 -166.160 1.00 67.75  ? 295 LEU A CB  1 
ATOM 2068 C CG  . LEU A 1 295 ? 24.251  -56.126 -164.815 1.00 65.66  ? 295 LEU A CG  1 
ATOM 2069 C CD1 . LEU A 1 295 ? 24.714  -57.423 -164.201 1.00 73.40  ? 295 LEU A CD1 1 
ATOM 2070 C CD2 . LEU A 1 295 ? 24.546  -54.969 -163.891 1.00 69.62  ? 295 LEU A CD2 1 
ATOM 2071 N N   . THR A 1 296 ? 26.188  -53.677 -168.357 1.00 73.39  ? 296 THR A N   1 
ATOM 2072 C CA  . THR A 1 296 ? 26.834  -53.509 -169.647 1.00 75.89  ? 296 THR A CA  1 
ATOM 2073 C C   . THR A 1 296 ? 27.773  -54.675 -169.911 1.00 78.44  ? 296 THR A C   1 
ATOM 2074 O O   . THR A 1 296 ? 28.540  -55.078 -169.031 1.00 79.76  ? 296 THR A O   1 
ATOM 2075 C CB  . THR A 1 296 ? 27.604  -52.193 -169.691 1.00 81.28  ? 296 THR A CB  1 
ATOM 2076 O OG1 . THR A 1 296 ? 26.886  -51.193 -168.959 1.00 83.44  ? 296 THR A OG1 1 
ATOM 2077 C CG2 . THR A 1 296 ? 27.773  -51.731 -171.124 1.00 82.57  ? 296 THR A CG2 1 
ATOM 2078 N N   . GLY A 1 297 ? 27.704  -55.224 -171.118 1.00 76.53  ? 297 GLY A N   1 
ATOM 2079 C CA  . GLY A 1 297 ? 28.618  -56.272 -171.517 1.00 77.54  ? 297 GLY A CA  1 
ATOM 2080 C C   . GLY A 1 297 ? 28.311  -57.647 -170.976 1.00 81.89  ? 297 GLY A C   1 
ATOM 2081 O O   . GLY A 1 297 ? 29.131  -58.556 -171.150 1.00 84.43  ? 297 GLY A O   1 
ATOM 2082 N N   . VAL A 1 298 ? 27.168  -57.836 -170.326 1.00 83.18  ? 298 VAL A N   1 
ATOM 2083 C CA  . VAL A 1 298 ? 26.771  -59.131 -169.784 1.00 80.03  ? 298 VAL A CA  1 
ATOM 2084 C C   . VAL A 1 298 ? 25.504  -59.568 -170.500 1.00 79.36  ? 298 VAL A C   1 
ATOM 2085 O O   . VAL A 1 298 ? 24.519  -58.821 -170.537 1.00 76.66  ? 298 VAL A O   1 
ATOM 2086 C CB  . VAL A 1 298 ? 26.551  -59.075 -168.266 1.00 78.57  ? 298 VAL A CB  1 
ATOM 2087 C CG1 . VAL A 1 298 ? 26.460  -60.474 -167.705 1.00 79.36  ? 298 VAL A CG1 1 
ATOM 2088 C CG2 . VAL A 1 298 ? 27.676  -58.310 -167.602 1.00 78.73  ? 298 VAL A CG2 1 
ATOM 2089 N N   . ALA A 1 299 ? 25.529  -60.770 -171.066 1.00 83.63  ? 299 ALA A N   1 
ATOM 2090 C CA  . ALA A 1 299 ? 24.403  -61.274 -171.833 1.00 85.38  ? 299 ALA A CA  1 
ATOM 2091 C C   . ALA A 1 299 ? 23.376  -61.934 -170.918 1.00 84.07  ? 299 ALA A C   1 
ATOM 2092 O O   . ALA A 1 299 ? 23.609  -62.152 -169.727 1.00 88.74  ? 299 ALA A O   1 
ATOM 2093 C CB  . ALA A 1 299 ? 24.879  -62.258 -172.898 1.00 81.37  ? 299 ALA A CB  1 
ATOM 2094 N N   . ALA A 1 300 ? 22.224  -62.263 -171.496 1.00 78.13  ? 300 ALA A N   1 
ATOM 2095 C CA  . ALA A 1 300 ? 21.164  -62.903 -170.734 1.00 78.19  ? 300 ALA A CA  1 
ATOM 2096 C C   . ALA A 1 300 ? 21.569  -64.318 -170.345 1.00 81.33  ? 300 ALA A C   1 
ATOM 2097 O O   . ALA A 1 300 ? 22.471  -64.914 -170.936 1.00 86.36  ? 300 ALA A O   1 
ATOM 2098 C CB  . ALA A 1 300 ? 19.869  -62.931 -171.539 1.00 76.53  ? 300 ALA A CB  1 
ATOM 2099 N N   . SER A 1 301 ? 20.882  -64.864 -169.344 1.00 71.82  ? 301 SER A N   1 
ATOM 2100 C CA  . SER A 1 301 ? 21.235  -66.186 -168.850 1.00 65.06  ? 301 SER A CA  1 
ATOM 2101 C C   . SER A 1 301 ? 20.878  -67.229 -169.896 1.00 71.57  ? 301 SER A C   1 
ATOM 2102 O O   . SER A 1 301 ? 19.749  -67.721 -169.936 1.00 82.80  ? 301 SER A O   1 
ATOM 2103 C CB  . SER A 1 301 ? 20.524  -66.485 -167.532 1.00 66.31  ? 301 SER A CB  1 
ATOM 2104 O OG  . SER A 1 301 ? 20.745  -65.453 -166.590 1.00 67.79  ? 301 SER A OG  1 
ATOM 2105 N N   . LEU A 1 302 ? 21.841  -67.567 -170.744 1.00 77.38  ? 302 LEU A N   1 
ATOM 2106 C CA  . LEU A 1 302 ? 21.586  -68.483 -171.840 1.00 80.90  ? 302 LEU A CA  1 
ATOM 2107 C C   . LEU A 1 302 ? 21.365  -69.898 -171.318 1.00 81.02  ? 302 LEU A C   1 
ATOM 2108 O O   . LEU A 1 302 ? 21.848  -70.279 -170.249 1.00 78.11  ? 302 LEU A O   1 
ATOM 2109 C CB  . LEU A 1 302 ? 22.752  -68.453 -172.825 1.00 80.00  ? 302 LEU A CB  1 
ATOM 2110 C CG  . LEU A 1 302 ? 22.743  -67.301 -173.830 1.00 80.55  ? 302 LEU A CG  1 
ATOM 2111 C CD1 . LEU A 1 302 ? 23.475  -67.688 -175.097 1.00 83.70  ? 302 LEU A CD1 1 
ATOM 2112 C CD2 . LEU A 1 302 ? 21.319  -66.880 -174.146 1.00 80.93  ? 302 LEU A CD2 1 
ATOM 2113 N N   . GLN A 1 303 ? 20.612  -70.674 -172.082 1.00 89.10  ? 303 GLN A N   1 
ATOM 2114 C CA  . GLN A 1 303 ? 20.391  -72.062 -171.705 1.00 85.98  ? 303 GLN A CA  1 
ATOM 2115 C C   . GLN A 1 303 ? 21.670  -72.869 -171.911 1.00 91.86  ? 303 GLN A C   1 
ATOM 2116 O O   . GLN A 1 303 ? 22.406  -72.630 -172.872 1.00 95.67  ? 303 GLN A O   1 
ATOM 2117 C CB  . GLN A 1 303 ? 19.262  -72.670 -172.525 1.00 86.82  ? 303 GLN A CB  1 
ATOM 2118 C CG  . GLN A 1 303 ? 17.975  -72.854 -171.758 1.00 87.02  ? 303 GLN A CG  1 
ATOM 2119 C CD  . GLN A 1 303 ? 16.877  -73.429 -172.618 1.00 90.09  ? 303 GLN A CD  1 
ATOM 2120 O OE1 . GLN A 1 303 ? 16.362  -74.509 -172.345 1.00 93.54  ? 303 GLN A OE1 1 
ATOM 2121 N NE2 . GLN A 1 303 ? 16.518  -72.711 -173.673 1.00 88.14  ? 303 GLN A NE2 1 
ATOM 2122 N N   . PRO A 1 304 ? 21.955  -73.819 -171.029 1.00 90.63  ? 304 PRO A N   1 
ATOM 2123 C CA  . PRO A 1 304 ? 23.180  -74.617 -171.167 1.00 89.02  ? 304 PRO A CA  1 
ATOM 2124 C C   . PRO A 1 304 ? 23.254  -75.385 -172.475 1.00 88.32  ? 304 PRO A C   1 
ATOM 2125 O O   . PRO A 1 304 ? 24.336  -75.556 -173.042 1.00 86.63  ? 304 PRO A O   1 
ATOM 2126 C CB  . PRO A 1 304 ? 23.098  -75.573 -169.972 1.00 85.94  ? 304 PRO A CB  1 
ATOM 2127 C CG  . PRO A 1 304 ? 22.297  -74.829 -168.967 1.00 82.08  ? 304 PRO A CG  1 
ATOM 2128 C CD  . PRO A 1 304 ? 21.254  -74.107 -169.769 1.00 84.08  ? 304 PRO A CD  1 
ATOM 2129 N N   . ALA A 1 305 ? 22.108  -75.848 -172.968 1.00 97.23  ? 305 ALA A N   1 
ATOM 2130 C CA  . ALA A 1 305 ? 22.079  -76.769 -174.110 1.00 97.87  ? 305 ALA A CA  1 
ATOM 2131 C C   . ALA A 1 305 ? 21.934  -76.022 -175.432 1.00 99.70  ? 305 ALA A C   1 
ATOM 2132 O O   . ALA A 1 305 ? 22.792  -76.126 -176.312 1.00 101.06 ? 305 ALA A O   1 
ATOM 2133 C CB  . ALA A 1 305 ? 20.954  -77.788 -173.929 1.00 96.64  ? 305 ALA A CB  1 
ATOM 2134 N N   . ASN A 1 306 ? 20.845  -75.267 -175.585 1.00 97.92  ? 306 ASN A N   1 
ATOM 2135 C CA  . ASN A 1 306 ? 20.565  -74.631 -176.866 1.00 98.82  ? 306 ASN A CA  1 
ATOM 2136 C C   . ASN A 1 306 ? 21.152  -73.233 -176.970 1.00 96.91  ? 306 ASN A C   1 
ATOM 2137 O O   . ASN A 1 306 ? 21.042  -72.612 -178.031 1.00 100.22 ? 306 ASN A O   1 
ATOM 2138 C CB  . ASN A 1 306 ? 19.058  -74.570 -177.110 1.00 93.92  ? 306 ASN A CB  1 
ATOM 2139 C CG  . ASN A 1 306 ? 18.288  -74.161 -175.877 1.00 95.98  ? 306 ASN A CG  1 
ATOM 2140 O OD1 . ASN A 1 306 ? 18.071  -72.976 -175.634 1.00 95.94  ? 306 ASN A OD1 1 
ATOM 2141 N ND2 . ASN A 1 306 ? 17.862  -75.142 -175.094 1.00 94.48  ? 306 ASN A ND2 1 
ATOM 2142 N N   . GLN A 1 307 ? 21.762  -72.774 -175.877 1.00 87.29  ? 307 GLN A N   1 
ATOM 2143 C CA  . GLN A 1 307 ? 22.365  -71.419 -175.846 1.00 89.05  ? 307 GLN A CA  1 
ATOM 2144 C C   . GLN A 1 307 ? 21.303  -70.393 -176.250 1.00 91.34  ? 307 GLN A C   1 
ATOM 2145 O O   . GLN A 1 307 ? 21.622  -69.516 -177.067 1.00 94.79  ? 307 GLN A O   1 
ATOM 2146 C CB  . GLN A 1 307 ? 23.607  -71.370 -176.730 1.00 88.10  ? 307 GLN A CB  1 
ATOM 2147 C CG  . GLN A 1 307 ? 24.709  -72.322 -176.286 1.00 87.12  ? 307 GLN A CG  1 
ATOM 2148 C CD  . GLN A 1 307 ? 25.190  -72.052 -174.878 1.00 90.63  ? 307 GLN A CD  1 
ATOM 2149 O OE1 . GLN A 1 307 ? 25.875  -71.060 -174.611 1.00 87.56  ? 307 GLN A OE1 1 
ATOM 2150 N NE2 . GLN A 1 307 ? 24.835  -72.938 -173.960 1.00 92.48  ? 307 GLN A NE2 1 
ATOM 2151 N N   . ARG A 1 308 ? 20.089  -70.516 -175.717 1.00 87.55  ? 308 ARG A N   1 
ATOM 2152 C CA  . ARG A 1 308 ? 19.039  -69.500 -175.978 1.00 86.54  ? 308 ARG A CA  1 
ATOM 2153 C C   . ARG A 1 308 ? 18.463  -69.069 -174.624 1.00 86.21  ? 308 ARG A C   1 
ATOM 2154 O O   . ARG A 1 308 ? 18.510  -69.882 -173.689 1.00 88.78  ? 308 ARG A O   1 
ATOM 2155 C CB  . ARG A 1 308 ? 17.953  -70.074 -176.887 1.00 82.87  ? 308 ARG A CB  1 
ATOM 2156 C CG  . ARG A 1 308 ? 18.458  -70.633 -178.208 1.00 83.15  ? 308 ARG A CG  1 
ATOM 2157 C CD  . ARG A 1 308 ? 17.672  -70.094 -179.388 1.00 89.29  ? 308 ARG A CD  1 
ATOM 2158 N NE  . ARG A 1 308 ? 18.366  -68.971 -180.026 1.00 91.80  ? 308 ARG A NE  1 
ATOM 2159 C CZ  . ARG A 1 308 ? 18.551  -67.792 -179.454 1.00 82.82  ? 308 ARG A CZ  1 
ATOM 2160 N NH1 . ARG A 1 308 ? 17.512  -67.048 -179.126 1.00 81.60  ? 308 ARG A NH1 1 
ATOM 2161 N NH2 . ARG A 1 308 ? 19.775  -67.365 -179.204 1.00 75.09  ? 308 ARG A NH2 1 
ATOM 2162 N N   . PRO A 1 309 ? 17.950  -67.835 -174.458 1.00 77.05  ? 309 PRO A N   1 
ATOM 2163 C CA  . PRO A 1 309 ? 17.464  -67.398 -173.159 1.00 77.05  ? 309 PRO A CA  1 
ATOM 2164 C C   . PRO A 1 309 ? 16.508  -68.386 -172.521 1.00 75.58  ? 309 PRO A C   1 
ATOM 2165 O O   . PRO A 1 309 ? 15.807  -69.102 -173.249 1.00 79.18  ? 309 PRO A O   1 
ATOM 2166 C CB  . PRO A 1 309 ? 16.791  -66.081 -173.502 1.00 77.16  ? 309 PRO A CB  1 
ATOM 2167 C CG  . PRO A 1 309 ? 16.611  -66.116 -174.998 1.00 80.45  ? 309 PRO A CG  1 
ATOM 2168 C CD  . PRO A 1 309 ? 17.845  -66.832 -175.489 1.00 77.34  ? 309 PRO A CD  1 
ATOM 2169 N N   . LEU A 1 310 ? 16.421  -68.396 -171.192 1.00 64.65  ? 310 LEU A N   1 
ATOM 2170 C CA  . LEU A 1 310 ? 15.620  -69.397 -170.503 1.00 70.34  ? 310 LEU A CA  1 
ATOM 2171 C C   . LEU A 1 310 ? 14.136  -69.217 -170.799 1.00 76.38  ? 310 LEU A C   1 
ATOM 2172 O O   . LEU A 1 310 ? 13.665  -68.113 -171.081 1.00 81.64  ? 310 LEU A O   1 
ATOM 2173 C CB  . LEU A 1 310 ? 15.851  -69.310 -168.998 1.00 73.48  ? 310 LEU A CB  1 
ATOM 2174 C CG  . LEU A 1 310 ? 17.297  -69.191 -168.532 1.00 69.12  ? 310 LEU A CG  1 
ATOM 2175 C CD1 . LEU A 1 310 ? 17.351  -68.981 -167.035 1.00 67.26  ? 310 LEU A CD1 1 
ATOM 2176 C CD2 . LEU A 1 310 ? 18.079  -70.419 -168.928 1.00 76.06  ? 310 LEU A CD2 1 
ATOM 2177 N N   . ILE A 1 311 ? 13.400  -70.324 -170.745 1.00 76.09  ? 311 ILE A N   1 
ATOM 2178 C CA  . ILE A 1 311 ? 11.950  -70.288 -170.889 1.00 75.93  ? 311 ILE A CA  1 
ATOM 2179 C C   . ILE A 1 311 ? 11.336  -69.938 -169.541 1.00 77.97  ? 311 ILE A C   1 
ATOM 2180 O O   . ILE A 1 311 ? 12.018  -69.965 -168.512 1.00 83.80  ? 311 ILE A O   1 
ATOM 2181 C CB  . ILE A 1 311 ? 11.400  -71.622 -171.418 1.00 76.43  ? 311 ILE A CB  1 
ATOM 2182 C CG1 . ILE A 1 311 ? 12.136  -72.791 -170.774 1.00 80.38  ? 311 ILE A CG1 1 
ATOM 2183 C CG2 . ILE A 1 311 ? 11.537  -71.684 -172.923 1.00 76.71  ? 311 ILE A CG2 1 
ATOM 2184 C CD1 . ILE A 1 311 ? 11.325  -74.061 -170.730 1.00 80.53  ? 311 ILE A CD1 1 
ATOM 2185 N N   . SER A 1 312 ? 10.043  -69.611 -169.541 1.00 73.92  ? 312 SER A N   1 
ATOM 2186 C CA  . SER A 1 312 ? 9.403   -69.118 -168.327 1.00 71.48  ? 312 SER A CA  1 
ATOM 2187 C C   . SER A 1 312 ? 9.410   -70.152 -167.211 1.00 73.64  ? 312 SER A C   1 
ATOM 2188 O O   . SER A 1 312 ? 9.419   -69.785 -166.032 1.00 78.78  ? 312 SER A O   1 
ATOM 2189 C CB  . SER A 1 312 ? 7.972   -68.689 -168.632 1.00 73.48  ? 312 SER A CB  1 
ATOM 2190 O OG  . SER A 1 312 ? 7.181   -69.807 -168.985 1.00 78.82  ? 312 SER A OG  1 
ATOM 2191 N N   . ILE A 1 313 ? 9.394   -71.441 -167.550 1.00 71.38  ? 313 ILE A N   1 
ATOM 2192 C CA  . ILE A 1 313 ? 9.379   -72.473 -166.517 1.00 70.78  ? 313 ILE A CA  1 
ATOM 2193 C C   . ILE A 1 313 ? 10.674  -72.447 -165.718 1.00 73.45  ? 313 ILE A C   1 
ATOM 2194 O O   . ILE A 1 313 ? 10.666  -72.550 -164.486 1.00 76.27  ? 313 ILE A O   1 
ATOM 2195 C CB  . ILE A 1 313 ? 9.136   -73.858 -167.140 1.00 69.66  ? 313 ILE A CB  1 
ATOM 2196 C CG1 . ILE A 1 313 ? 8.203   -73.753 -168.346 1.00 73.03  ? 313 ILE A CG1 1 
ATOM 2197 C CG2 . ILE A 1 313 ? 8.555   -74.799 -166.108 1.00 68.11  ? 313 ILE A CG2 1 
ATOM 2198 C CD1 . ILE A 1 313 ? 6.788   -73.369 -167.992 1.00 73.61  ? 313 ILE A CD1 1 
ATOM 2199 N N   . GLN A 1 314 ? 11.807  -72.318 -166.406 1.00 76.04  ? 314 GLN A N   1 
ATOM 2200 C CA  . GLN A 1 314 ? 13.093  -72.272 -165.721 1.00 78.37  ? 314 GLN A CA  1 
ATOM 2201 C C   . GLN A 1 314 ? 13.211  -71.027 -164.854 1.00 82.40  ? 314 GLN A C   1 
ATOM 2202 O O   . GLN A 1 314 ? 13.738  -71.085 -163.736 1.00 89.13  ? 314 GLN A O   1 
ATOM 2203 C CB  . GLN A 1 314 ? 14.214  -72.334 -166.751 1.00 75.98  ? 314 GLN A CB  1 
ATOM 2204 C CG  . GLN A 1 314 ? 14.271  -73.659 -167.480 1.00 81.22  ? 314 GLN A CG  1 
ATOM 2205 C CD  . GLN A 1 314 ? 14.863  -73.536 -168.863 1.00 84.31  ? 314 GLN A CD  1 
ATOM 2206 O OE1 . GLN A 1 314 ? 15.120  -72.435 -169.343 1.00 84.20  ? 314 GLN A OE1 1 
ATOM 2207 N NE2 . GLN A 1 314 ? 15.081  -74.669 -169.516 1.00 83.84  ? 314 GLN A NE2 1 
ATOM 2208 N N   . LYS A 1 315 ? 12.725  -69.890 -165.352 1.00 72.54  ? 315 LYS A N   1 
ATOM 2209 C CA  . LYS A 1 315 ? 12.721  -68.680 -164.542 1.00 69.26  ? 315 LYS A CA  1 
ATOM 2210 C C   . LYS A 1 315 ? 11.844  -68.853 -163.311 1.00 74.78  ? 315 LYS A C   1 
ATOM 2211 O O   . LYS A 1 315 ? 12.189  -68.381 -162.224 1.00 77.80  ? 315 LYS A O   1 
ATOM 2212 C CB  . LYS A 1 315 ? 12.253  -67.497 -165.383 1.00 73.27  ? 315 LYS A CB  1 
ATOM 2213 C CG  . LYS A 1 315 ? 13.221  -67.136 -166.487 1.00 69.37  ? 315 LYS A CG  1 
ATOM 2214 C CD  . LYS A 1 315 ? 12.679  -66.043 -167.378 1.00 69.74  ? 315 LYS A CD  1 
ATOM 2215 C CE  . LYS A 1 315 ? 13.429  -66.022 -168.692 1.00 72.89  ? 315 LYS A CE  1 
ATOM 2216 N NZ  . LYS A 1 315 ? 12.757  -65.184 -169.711 1.00 80.06  ? 315 LYS A NZ  1 
ATOM 2217 N N   . SER A 1 316 ? 10.706  -69.532 -163.460 1.00 78.67  ? 316 SER A N   1 
ATOM 2218 C CA  . SER A 1 316 ? 9.856   -69.806 -162.308 1.00 78.00  ? 316 SER A CA  1 
ATOM 2219 C C   . SER A 1 316 ? 10.573  -70.692 -161.300 1.00 80.73  ? 316 SER A C   1 
ATOM 2220 O O   . SER A 1 316 ? 10.461  -70.484 -160.087 1.00 85.41  ? 316 SER A O   1 
ATOM 2221 C CB  . SER A 1 316 ? 8.551   -70.456 -162.759 1.00 76.93  ? 316 SER A CB  1 
ATOM 2222 O OG  . SER A 1 316 ? 7.634   -70.553 -161.685 1.00 82.24  ? 316 SER A OG  1 
ATOM 2223 N N   . ALA A 1 317 ? 11.308  -71.692 -161.782 1.00 75.19  ? 317 ALA A N   1 
ATOM 2224 C CA  . ALA A 1 317 ? 12.073  -72.548 -160.881 1.00 71.23  ? 317 ALA A CA  1 
ATOM 2225 C C   . ALA A 1 317 ? 13.110  -71.740 -160.113 1.00 78.39  ? 317 ALA A C   1 
ATOM 2226 O O   . ALA A 1 317 ? 13.245  -71.875 -158.889 1.00 85.33  ? 317 ALA A O   1 
ATOM 2227 C CB  . ALA A 1 317 ? 12.742  -73.669 -161.672 1.00 70.34  ? 317 ALA A CB  1 
ATOM 2228 N N   . LEU A 1 318 ? 13.841  -70.876 -160.819 1.00 82.03  ? 318 LEU A N   1 
ATOM 2229 C CA  . LEU A 1 318 ? 14.845  -70.048 -160.159 1.00 80.31  ? 318 LEU A CA  1 
ATOM 2230 C C   . LEU A 1 318 ? 14.203  -69.119 -159.139 1.00 78.04  ? 318 LEU A C   1 
ATOM 2231 O O   . LEU A 1 318 ? 14.747  -68.910 -158.049 1.00 75.37  ? 318 LEU A O   1 
ATOM 2232 C CB  . LEU A 1 318 ? 15.629  -69.248 -161.193 1.00 77.23  ? 318 LEU A CB  1 
ATOM 2233 C CG  . LEU A 1 318 ? 16.751  -70.012 -161.886 1.00 71.59  ? 318 LEU A CG  1 
ATOM 2234 C CD1 . LEU A 1 318 ? 17.429  -69.137 -162.916 1.00 76.89  ? 318 LEU A CD1 1 
ATOM 2235 C CD2 . LEU A 1 318 ? 17.742  -70.496 -160.857 1.00 72.65  ? 318 LEU A CD2 1 
ATOM 2236 N N   . ASP A 1 319 ? 13.045  -68.552 -159.477 1.00 78.02  ? 319 ASP A N   1 
ATOM 2237 C CA  . ASP A 1 319 ? 12.321  -67.721 -158.524 1.00 81.27  ? 319 ASP A CA  1 
ATOM 2238 C C   . ASP A 1 319 ? 11.936  -68.518 -157.288 1.00 86.19  ? 319 ASP A C   1 
ATOM 2239 O O   . ASP A 1 319 ? 12.055  -68.027 -156.160 1.00 91.93  ? 319 ASP A O   1 
ATOM 2240 C CB  . ASP A 1 319 ? 11.080  -67.132 -159.186 1.00 85.55  ? 319 ASP A CB  1 
ATOM 2241 C CG  . ASP A 1 319 ? 10.247  -66.314 -158.229 1.00 92.29  ? 319 ASP A CG  1 
ATOM 2242 O OD1 . ASP A 1 319 ? 10.836  -65.585 -157.404 1.00 91.79  ? 319 ASP A OD1 1 
ATOM 2243 O OD2 . ASP A 1 319 ? 9.003   -66.402 -158.298 1.00 91.51  ? 319 ASP A OD2 1 
ATOM 2244 N N   . THR A 1 320 ? 11.467  -69.750 -157.479 1.00 84.65  ? 320 THR A N   1 
ATOM 2245 C CA  . THR A 1 320 ? 11.144  -70.598 -156.339 1.00 81.95  ? 320 THR A CA  1 
ATOM 2246 C C   . THR A 1 320 ? 12.378  -70.885 -155.501 1.00 82.98  ? 320 THR A C   1 
ATOM 2247 O O   . THR A 1 320 ? 12.268  -71.107 -154.291 1.00 78.99  ? 320 THR A O   1 
ATOM 2248 C CB  . THR A 1 320 ? 10.516  -71.905 -156.812 1.00 86.11  ? 320 THR A CB  1 
ATOM 2249 O OG1 . THR A 1 320 ? 9.703   -71.654 -157.962 1.00 92.43  ? 320 THR A OG1 1 
ATOM 2250 C CG2 . THR A 1 320 ? 9.657   -72.499 -155.714 1.00 89.95  ? 320 THR A CG2 1 
ATOM 2251 N N   . ARG A 1 321 ? 13.554  -70.886 -156.121 1.00 83.54  ? 321 ARG A N   1 
ATOM 2252 C CA  . ARG A 1 321 ? 14.804  -71.050 -155.394 1.00 78.52  ? 321 ARG A CA  1 
ATOM 2253 C C   . ARG A 1 321 ? 15.364  -69.734 -154.877 1.00 81.87  ? 321 ARG A C   1 
ATOM 2254 O O   . ARG A 1 321 ? 16.439  -69.734 -154.270 1.00 84.87  ? 321 ARG A O   1 
ATOM 2255 C CB  . ARG A 1 321 ? 15.840  -71.736 -156.283 1.00 74.89  ? 321 ARG A CB  1 
ATOM 2256 C CG  . ARG A 1 321 ? 15.483  -73.164 -156.617 1.00 79.64  ? 321 ARG A CG  1 
ATOM 2257 C CD  . ARG A 1 321 ? 16.518  -73.808 -157.512 1.00 80.47  ? 321 ARG A CD  1 
ATOM 2258 N NE  . ARG A 1 321 ? 16.260  -75.229 -157.710 1.00 78.83  ? 321 ARG A NE  1 
ATOM 2259 C CZ  . ARG A 1 321 ? 15.209  -75.720 -158.354 1.00 83.68  ? 321 ARG A CZ  1 
ATOM 2260 N NH1 . ARG A 1 321 ? 14.296  -74.932 -158.893 1.00 89.40  ? 321 ARG A NH1 1 
ATOM 2261 N NH2 . ARG A 1 321 ? 15.077  -77.038 -158.466 1.00 83.25  ? 321 ARG A NH2 1 
ATOM 2262 N N   . SER A 1 322 ? 14.663  -68.620 -155.101 1.00 78.46  ? 322 SER A N   1 
ATOM 2263 C CA  . SER A 1 322 ? 15.093  -67.291 -154.661 1.00 73.03  ? 322 SER A CA  1 
ATOM 2264 C C   . SER A 1 322 ? 16.456  -66.913 -155.223 1.00 71.29  ? 322 SER A C   1 
ATOM 2265 O O   . SER A 1 322 ? 17.281  -66.318 -154.530 1.00 65.24  ? 322 SER A O   1 
ATOM 2266 C CB  . SER A 1 322 ? 15.104  -67.181 -153.135 1.00 68.81  ? 322 SER A CB  1 
ATOM 2267 O OG  . SER A 1 322 ? 13.789  -67.250 -152.617 1.00 78.06  ? 322 SER A OG  1 
ATOM 2268 N N   . CYS A 1 323 ? 16.706  -67.257 -156.480 1.00 73.30  ? 323 CYS A N   1 
ATOM 2269 C CA  . CYS A 1 323 ? 17.932  -66.861 -157.147 1.00 66.42  ? 323 CYS A CA  1 
ATOM 2270 C C   . CYS A 1 323 ? 17.714  -65.591 -157.957 1.00 67.64  ? 323 CYS A C   1 
ATOM 2271 O O   . CYS A 1 323 ? 16.691  -64.916 -157.854 1.00 76.16  ? 323 CYS A O   1 
ATOM 2272 C CB  . CYS A 1 323 ? 18.445  -67.979 -158.046 1.00 71.85  ? 323 CYS A CB  1 
ATOM 2273 S SG  . CYS A 1 323 ? 19.570  -69.093 -157.227 1.00 87.47  ? 323 CYS A SG  1 
ATOM 2274 N N   . ASN A 1 324 ? 18.706  -65.261 -158.769 1.00 65.35  ? 324 ASN A N   1 
ATOM 2275 C CA  . ASN A 1 324 ? 18.644  -64.129 -159.674 1.00 58.27  ? 324 ASN A CA  1 
ATOM 2276 C C   . ASN A 1 324 ? 19.099  -64.581 -161.050 1.00 72.28  ? 324 ASN A C   1 
ATOM 2277 O O   . ASN A 1 324 ? 20.010  -65.403 -161.175 1.00 88.31  ? 324 ASN A O   1 
ATOM 2278 C CB  . ASN A 1 324 ? 19.515  -62.986 -159.175 1.00 65.55  ? 324 ASN A CB  1 
ATOM 2279 C CG  . ASN A 1 324 ? 19.026  -62.424 -157.866 1.00 70.75  ? 324 ASN A CG  1 
ATOM 2280 O OD1 . ASN A 1 324 ? 17.853  -62.102 -157.719 1.00 78.12  ? 324 ASN A OD1 1 
ATOM 2281 N ND2 . ASN A 1 324 ? 19.921  -62.315 -156.900 1.00 74.66  ? 324 ASN A ND2 1 
ATOM 2282 N N   . PHE A 1 325 ? 18.456  -64.051 -162.080 1.00 71.93  ? 325 PHE A N   1 
ATOM 2283 C CA  . PHE A 1 325 ? 18.761  -64.413 -163.452 1.00 68.95  ? 325 PHE A CA  1 
ATOM 2284 C C   . PHE A 1 325 ? 18.712  -63.156 -164.298 1.00 73.06  ? 325 PHE A C   1 
ATOM 2285 O O   . PHE A 1 325 ? 18.098  -62.157 -163.919 1.00 85.83  ? 325 PHE A O   1 
ATOM 2286 C CB  . PHE A 1 325 ? 17.776  -65.454 -163.983 1.00 70.01  ? 325 PHE A CB  1 
ATOM 2287 C CG  . PHE A 1 325 ? 16.342  -65.087 -163.761 1.00 76.29  ? 325 PHE A CG  1 
ATOM 2288 C CD1 . PHE A 1 325 ? 15.693  -65.450 -162.599 1.00 77.48  ? 325 PHE A CD1 1 
ATOM 2289 C CD2 . PHE A 1 325 ? 15.646  -64.366 -164.710 1.00 74.83  ? 325 PHE A CD2 1 
ATOM 2290 C CE1 . PHE A 1 325 ? 14.376  -65.107 -162.390 1.00 77.01  ? 325 PHE A CE1 1 
ATOM 2291 C CE2 . PHE A 1 325 ? 14.332  -64.021 -164.506 1.00 79.19  ? 325 PHE A CE2 1 
ATOM 2292 C CZ  . PHE A 1 325 ? 13.695  -64.392 -163.344 1.00 76.63  ? 325 PHE A CZ  1 
ATOM 2293 N N   . ILE A 1 326 ? 19.371  -63.200 -165.449 1.00 60.80  ? 326 ILE A N   1 
ATOM 2294 C CA  . ILE A 1 326 ? 19.371  -62.071 -166.367 1.00 67.91  ? 326 ILE A CA  1 
ATOM 2295 C C   . ILE A 1 326 ? 18.262  -62.314 -167.384 1.00 69.82  ? 326 ILE A C   1 
ATOM 2296 O O   . ILE A 1 326 ? 18.454  -63.000 -168.387 1.00 70.86  ? 326 ILE A O   1 
ATOM 2297 C CB  . ILE A 1 326 ? 20.733  -61.878 -167.030 1.00 68.94  ? 326 ILE A CB  1 
ATOM 2298 C CG1 . ILE A 1 326 ? 21.804  -61.716 -165.954 1.00 68.27  ? 326 ILE A CG1 1 
ATOM 2299 C CG2 . ILE A 1 326 ? 20.710  -60.660 -167.921 1.00 68.20  ? 326 ILE A CG2 1 
ATOM 2300 C CD1 . ILE A 1 326 ? 23.099  -61.160 -166.464 1.00 66.90  ? 326 ILE A CD1 1 
ATOM 2301 N N   . ASP A 1 327 ? 17.095  -61.743 -167.117 1.00 79.13  ? 327 ASP A N   1 
ATOM 2302 C CA  . ASP A 1 327 ? 15.942  -61.894 -167.987 1.00 77.60  ? 327 ASP A CA  1 
ATOM 2303 C C   . ASP A 1 327 ? 16.134  -61.112 -169.276 1.00 83.25  ? 327 ASP A C   1 
ATOM 2304 O O   . ASP A 1 327 ? 16.923  -60.169 -169.344 1.00 87.73  ? 327 ASP A O   1 
ATOM 2305 C CB  . ASP A 1 327 ? 14.678  -61.418 -167.275 1.00 78.26  ? 327 ASP A CB  1 
ATOM 2306 C CG  . ASP A 1 327 ? 13.415  -61.938 -167.916 1.00 86.72  ? 327 ASP A CG  1 
ATOM 2307 O OD1 . ASP A 1 327 ? 13.512  -62.590 -168.976 1.00 92.88  ? 327 ASP A OD1 1 
ATOM 2308 O OD2 . ASP A 1 327 ? 12.324  -61.690 -167.364 1.00 84.24  ? 327 ASP A OD2 1 
ATOM 2309 N N   . LEU A 1 328 ? 15.402  -61.518 -170.308 1.00 82.25  ? 328 LEU A N   1 
ATOM 2310 C CA  . LEU A 1 328 ? 15.446  -60.864 -171.613 1.00 82.36  ? 328 LEU A CA  1 
ATOM 2311 C C   . LEU A 1 328 ? 14.071  -60.268 -171.891 1.00 87.97  ? 328 LEU A C   1 
ATOM 2312 O O   . LEU A 1 328 ? 13.197  -60.918 -172.465 1.00 89.61  ? 328 LEU A O   1 
ATOM 2313 C CB  . LEU A 1 328 ? 15.856  -61.851 -172.696 1.00 82.85  ? 328 LEU A CB  1 
ATOM 2314 C CG  . LEU A 1 328 ? 16.458  -61.254 -173.966 1.00 84.69  ? 328 LEU A CG  1 
ATOM 2315 C CD1 . LEU A 1 328 ? 17.300  -60.043 -173.629 1.00 85.40  ? 328 LEU A CD1 1 
ATOM 2316 C CD2 . LEU A 1 328 ? 17.283  -62.291 -174.703 1.00 86.11  ? 328 LEU A CD2 1 
ATOM 2317 N N   . ASP A 1 329 ? 13.877  -59.017 -171.480 1.00 106.45 ? 329 ASP A N   1 
ATOM 2318 C CA  . ASP A 1 329 ? 12.615  -58.314 -171.695 1.00 107.72 ? 329 ASP A CA  1 
ATOM 2319 C C   . ASP A 1 329 ? 12.675  -57.600 -173.041 1.00 108.04 ? 329 ASP A C   1 
ATOM 2320 O O   . ASP A 1 329 ? 13.272  -56.526 -173.157 1.00 106.21 ? 329 ASP A O   1 
ATOM 2321 C CB  . ASP A 1 329 ? 12.341  -57.325 -170.567 1.00 109.07 ? 329 ASP A CB  1 
ATOM 2322 C CG  . ASP A 1 329 ? 11.315  -56.273 -170.954 1.00 112.41 ? 329 ASP A CG  1 
ATOM 2323 O OD1 . ASP A 1 329 ? 10.104  -56.573 -170.896 1.00 110.37 ? 329 ASP A OD1 1 
ATOM 2324 O OD2 . ASP A 1 329 ? 11.719  -55.147 -171.318 1.00 108.62 ? 329 ASP A OD2 1 
ATOM 2325 N N   . GLY A 1 330 ? 12.071  -58.202 -174.059 1.00 103.51 ? 330 GLY A N   1 
ATOM 2326 C CA  . GLY A 1 330 ? 12.010  -57.582 -175.362 1.00 102.18 ? 330 GLY A CA  1 
ATOM 2327 C C   . GLY A 1 330 ? 13.339  -57.411 -176.059 1.00 104.01 ? 330 GLY A C   1 
ATOM 2328 O O   . GLY A 1 330 ? 13.401  -56.686 -177.058 1.00 108.04 ? 330 GLY A O   1 
ATOM 2329 N N   . GLY A 1 331 ? 14.402  -58.040 -175.571 1.00 99.52  ? 331 GLY A N   1 
ATOM 2330 C CA  . GLY A 1 331 ? 15.696  -57.914 -176.204 1.00 99.29  ? 331 GLY A CA  1 
ATOM 2331 C C   . GLY A 1 331 ? 16.699  -57.149 -175.368 1.00 100.97 ? 331 GLY A C   1 
ATOM 2332 O O   . GLY A 1 331 ? 17.815  -56.881 -175.823 1.00 106.43 ? 331 GLY A O   1 
ATOM 2333 N N   . VAL A 1 332 ? 16.319  -56.789 -174.150 1.00 85.79  ? 332 VAL A N   1 
ATOM 2334 C CA  . VAL A 1 332 ? 17.185  -56.069 -173.228 1.00 83.90  ? 332 VAL A CA  1 
ATOM 2335 C C   . VAL A 1 332 ? 17.490  -56.988 -172.051 1.00 85.76  ? 332 VAL A C   1 
ATOM 2336 O O   . VAL A 1 332 ? 16.573  -57.394 -171.331 1.00 88.16  ? 332 VAL A O   1 
ATOM 2337 C CB  . VAL A 1 332 ? 16.550  -54.757 -172.742 1.00 82.32  ? 332 VAL A CB  1 
ATOM 2338 C CG1 . VAL A 1 332 ? 17.415  -54.120 -171.680 1.00 80.95  ? 332 VAL A CG1 1 
ATOM 2339 C CG2 . VAL A 1 332 ? 16.361  -53.813 -173.906 1.00 84.83  ? 332 VAL A CG2 1 
ATOM 2340 N N   . PRO A 1 333 ? 18.747  -57.344 -171.811 1.00 73.12  ? 333 PRO A N   1 
ATOM 2341 C CA  . PRO A 1 333 ? 19.077  -58.263 -170.713 1.00 70.87  ? 333 PRO A CA  1 
ATOM 2342 C C   . PRO A 1 333 ? 19.084  -57.540 -169.377 1.00 71.57  ? 333 PRO A C   1 
ATOM 2343 O O   . PRO A 1 333 ? 19.967  -56.725 -169.097 1.00 73.60  ? 333 PRO A O   1 
ATOM 2344 C CB  . PRO A 1 333 ? 20.474  -58.772 -171.097 1.00 70.38  ? 333 PRO A CB  1 
ATOM 2345 C CG  . PRO A 1 333 ? 21.018  -57.783 -172.070 1.00 72.61  ? 333 PRO A CG  1 
ATOM 2346 C CD  . PRO A 1 333 ? 19.944  -56.834 -172.492 1.00 74.06  ? 333 PRO A CD  1 
ATOM 2347 N N   . VAL A 1 334 ? 18.100  -57.851 -168.539 1.00 69.41  ? 334 VAL A N   1 
ATOM 2348 C CA  . VAL A 1 334 ? 17.897  -57.178 -167.262 1.00 65.39  ? 334 VAL A CA  1 
ATOM 2349 C C   . VAL A 1 334 ? 17.944  -58.212 -166.151 1.00 71.63  ? 334 VAL A C   1 
ATOM 2350 O O   . VAL A 1 334 ? 17.218  -59.211 -166.199 1.00 77.28  ? 334 VAL A O   1 
ATOM 2351 C CB  . VAL A 1 334 ? 16.557  -56.425 -167.232 1.00 66.86  ? 334 VAL A CB  1 
ATOM 2352 C CG1 . VAL A 1 334 ? 16.366  -55.750 -165.895 1.00 68.72  ? 334 VAL A CG1 1 
ATOM 2353 C CG2 . VAL A 1 334 ? 16.494  -55.417 -168.355 1.00 74.79  ? 334 VAL A CG2 1 
ATOM 2354 N N   . VAL A 1 335 ? 18.793  -57.971 -165.149 1.00 66.10  ? 335 VAL A N   1 
ATOM 2355 C CA  . VAL A 1 335 ? 18.753  -58.783 -163.943 1.00 56.53  ? 335 VAL A CA  1 
ATOM 2356 C C   . VAL A 1 335 ? 17.392  -58.608 -163.298 1.00 58.91  ? 335 VAL A C   1 
ATOM 2357 O O   . VAL A 1 335 ? 16.831  -57.507 -163.286 1.00 69.55  ? 335 VAL A O   1 
ATOM 2358 C CB  . VAL A 1 335 ? 19.876  -58.380 -162.977 1.00 47.57  ? 335 VAL A CB  1 
ATOM 2359 C CG1 . VAL A 1 335 ? 19.832  -59.240 -161.737 1.00 55.84  ? 335 VAL A CG1 1 
ATOM 2360 C CG2 . VAL A 1 335 ? 21.217  -58.494 -163.658 1.00 61.97  ? 335 VAL A CG2 1 
ATOM 2361 N N   . ARG A 1 336 ? 16.836  -59.691 -162.771 1.00 51.47  ? 336 ARG A N   1 
ATOM 2362 C CA  . ARG A 1 336 ? 15.474  -59.634 -162.278 1.00 54.12  ? 336 ARG A CA  1 
ATOM 2363 C C   . ARG A 1 336 ? 15.382  -60.131 -160.847 1.00 49.96  ? 336 ARG A C   1 
ATOM 2364 O O   . ARG A 1 336 ? 16.107  -61.033 -160.423 1.00 41.60  ? 336 ARG A O   1 
ATOM 2365 C CB  . ARG A 1 336 ? 14.523  -60.435 -163.161 1.00 64.09  ? 336 ARG A CB  1 
ATOM 2366 C CG  . ARG A 1 336 ? 13.994  -59.643 -164.342 1.00 67.12  ? 336 ARG A CG  1 
ATOM 2367 C CD  . ARG A 1 336 ? 12.937  -58.629 -163.937 1.00 65.00  ? 336 ARG A CD  1 
ATOM 2368 N NE  . ARG A 1 336 ? 11.878  -59.204 -163.121 1.00 58.97  ? 336 ARG A NE  1 
ATOM 2369 C CZ  . ARG A 1 336 ? 10.986  -60.081 -163.555 1.00 59.77  ? 336 ARG A CZ  1 
ATOM 2370 N NH1 . ARG A 1 336 ? 10.989  -60.513 -164.805 1.00 59.89  ? 336 ARG A NH1 1 
ATOM 2371 N NH2 . ARG A 1 336 ? 10.061  -60.534 -162.716 1.00 64.30  ? 336 ARG A NH2 1 
ATOM 2372 N N   . ARG A 1 337 ? 14.469  -59.503 -160.117 1.00 68.37  ? 337 ARG A N   1 
ATOM 2373 C CA  . ARG A 1 337 ? 13.997  -59.779 -158.770 1.00 70.94  ? 337 ARG A CA  1 
ATOM 2374 C C   . ARG A 1 337 ? 14.988  -59.351 -157.698 1.00 70.95  ? 337 ARG A C   1 
ATOM 2375 O O   . ARG A 1 337 ? 14.607  -59.305 -156.531 1.00 74.40  ? 337 ARG A O   1 
ATOM 2376 C CB  . ARG A 1 337 ? 13.633  -61.260 -158.553 1.00 69.14  ? 337 ARG A CB  1 
ATOM 2377 C CG  . ARG A 1 337 ? 12.469  -61.456 -157.612 1.00 71.24  ? 337 ARG A CG  1 
ATOM 2378 C CD  . ARG A 1 337 ? 11.249  -60.724 -158.130 1.00 73.07  ? 337 ARG A CD  1 
ATOM 2379 N NE  . ARG A 1 337 ? 10.583  -61.452 -159.201 1.00 73.96  ? 337 ARG A NE  1 
ATOM 2380 C CZ  . ARG A 1 337 ? 9.779   -62.487 -159.010 1.00 76.37  ? 337 ARG A CZ  1 
ATOM 2381 N NH1 . ARG A 1 337 ? 9.521   -62.946 -157.798 1.00 78.16  ? 337 ARG A NH1 1 
ATOM 2382 N NH2 . ARG A 1 337 ? 9.213   -63.072 -160.061 1.00 74.48  ? 337 ARG A NH2 1 
ATOM 2383 N N   . GLY A 1 338 ? 16.225  -59.001 -158.048 1.00 65.56  ? 338 GLY A N   1 
ATOM 2384 C CA  . GLY A 1 338 ? 17.170  -58.369 -157.140 1.00 69.80  ? 338 GLY A CA  1 
ATOM 2385 C C   . GLY A 1 338 ? 17.107  -58.810 -155.693 1.00 72.19  ? 338 GLY A C   1 
ATOM 2386 O O   . GLY A 1 338 ? 17.183  -57.978 -154.787 1.00 78.57  ? 338 GLY A O   1 
ATOM 2387 N N   . ILE A 1 339 ? 16.956  -60.109 -155.456 1.00 57.48  ? 339 ILE A N   1 
ATOM 2388 C CA  . ILE A 1 339 ? 16.618  -60.615 -154.136 1.00 53.31  ? 339 ILE A CA  1 
ATOM 2389 C C   . ILE A 1 339 ? 17.736  -61.521 -153.650 1.00 57.67  ? 339 ILE A C   1 
ATOM 2390 O O   . ILE A 1 339 ? 18.514  -62.068 -154.433 1.00 65.58  ? 339 ILE A O   1 
ATOM 2391 C CB  . ILE A 1 339 ? 15.270  -61.361 -154.148 1.00 56.87  ? 339 ILE A CB  1 
ATOM 2392 C CG1 . ILE A 1 339 ? 14.585  -61.283 -152.788 1.00 57.46  ? 339 ILE A CG1 1 
ATOM 2393 C CG2 . ILE A 1 339 ? 15.460  -62.804 -154.556 1.00 65.14  ? 339 ILE A CG2 1 
ATOM 2394 C CD1 . ILE A 1 339 ? 13.102  -61.540 -152.869 1.00 60.85  ? 339 ILE A CD1 1 
ATOM 2395 N N   . THR A 1 340 ? 17.820  -61.663 -152.332 1.00 65.66  ? 340 THR A N   1 
ATOM 2396 C CA  . THR A 1 340 ? 18.775  -62.570 -151.720 1.00 68.74  ? 340 THR A CA  1 
ATOM 2397 C C   . THR A 1 340 ? 18.113  -63.913 -151.458 1.00 69.76  ? 340 THR A C   1 
ATOM 2398 O O   . THR A 1 340 ? 16.889  -64.031 -151.415 1.00 74.46  ? 340 THR A O   1 
ATOM 2399 C CB  . THR A 1 340 ? 19.309  -62.008 -150.406 1.00 69.49  ? 340 THR A CB  1 
ATOM 2400 O OG1 . THR A 1 340 ? 18.289  -62.089 -149.407 1.00 71.76  ? 340 THR A OG1 1 
ATOM 2401 C CG2 . THR A 1 340 ? 19.712  -60.563 -150.571 1.00 69.48  ? 340 THR A CG2 1 
ATOM 2402 N N   . SER A 1 341 ? 18.942  -64.934 -151.270 1.00 74.81  ? 341 SER A N   1 
ATOM 2403 C CA  . SER A 1 341 ? 18.413  -66.253 -150.965 1.00 78.59  ? 341 SER A CA  1 
ATOM 2404 C C   . SER A 1 341 ? 17.759  -66.228 -149.593 1.00 78.67  ? 341 SER A C   1 
ATOM 2405 O O   . SER A 1 341 ? 18.445  -66.282 -148.572 1.00 80.35  ? 341 SER A O   1 
ATOM 2406 C CB  . SER A 1 341 ? 19.524  -67.299 -151.014 1.00 81.48  ? 341 SER A CB  1 
ATOM 2407 O OG  . SER A 1 341 ? 19.788  -67.695 -152.347 1.00 83.48  ? 341 SER A OG  1 
ATOM 2408 N N   . GLY A 1 342 ? 16.437  -66.162 -149.551 1.00 77.40  ? 342 GLY A N   1 
ATOM 2409 C CA  . GLY A 1 342 ? 15.763  -66.014 -148.280 1.00 79.88  ? 342 GLY A CA  1 
ATOM 2410 C C   . GLY A 1 342 ? 14.642  -65.004 -148.342 1.00 86.78  ? 342 GLY A C   1 
ATOM 2411 O O   . GLY A 1 342 ? 13.934  -64.788 -147.355 1.00 90.81  ? 342 GLY A O   1 
ATOM 2412 N N   . GLY A 1 343 ? 14.477  -64.368 -149.497 1.00 89.10  ? 343 GLY A N   1 
ATOM 2413 C CA  . GLY A 1 343 ? 13.347  -63.505 -149.750 1.00 84.60  ? 343 GLY A CA  1 
ATOM 2414 C C   . GLY A 1 343 ? 13.563  -62.043 -149.431 1.00 80.67  ? 343 GLY A C   1 
ATOM 2415 O O   . GLY A 1 343 ? 12.693  -61.226 -149.748 1.00 89.72  ? 343 GLY A O   1 
ATOM 2416 N N   . GLU A 1 344 ? 14.680  -61.687 -148.810 1.00 65.69  ? 344 GLU A N   1 
ATOM 2417 C CA  . GLU A 1 344 ? 14.916  -60.296 -148.461 1.00 67.59  ? 344 GLU A CA  1 
ATOM 2418 C C   . GLU A 1 344 ? 15.498  -59.542 -149.646 1.00 74.47  ? 344 GLU A C   1 
ATOM 2419 O O   . GLU A 1 344 ? 16.363  -60.053 -150.360 1.00 86.20  ? 344 GLU A O   1 
ATOM 2420 C CB  . GLU A 1 344 ? 15.861  -60.195 -147.269 1.00 71.57  ? 344 GLU A CB  1 
ATOM 2421 C CG  . GLU A 1 344 ? 15.695  -58.926 -146.468 1.00 69.65  ? 344 GLU A CG  1 
ATOM 2422 C CD  . GLU A 1 344 ? 14.290  -58.762 -145.929 1.00 81.83  ? 344 GLU A CD  1 
ATOM 2423 O OE1 . GLU A 1 344 ? 13.415  -58.257 -146.664 1.00 86.97  ? 344 GLU A OE1 1 
ATOM 2424 O OE2 . GLU A 1 344 ? 14.059  -59.143 -144.765 1.00 91.77  ? 344 GLU A OE2 1 
ATOM 2425 N N   . TRP A 1 345 ? 15.016  -58.323 -149.856 1.00 50.87  ? 345 TRP A N   1 
ATOM 2426 C CA  . TRP A 1 345 ? 15.548  -57.498 -150.927 1.00 47.64  ? 345 TRP A CA  1 
ATOM 2427 C C   . TRP A 1 345 ? 16.980  -57.096 -150.618 1.00 57.02  ? 345 TRP A C   1 
ATOM 2428 O O   . TRP A 1 345 ? 17.354  -56.894 -149.462 1.00 69.92  ? 345 TRP A O   1 
ATOM 2429 C CB  . TRP A 1 345 ? 14.690  -56.254 -151.124 1.00 52.32  ? 345 TRP A CB  1 
ATOM 2430 C CG  . TRP A 1 345 ? 13.271  -56.566 -151.403 1.00 57.02  ? 345 TRP A CG  1 
ATOM 2431 C CD1 . TRP A 1 345 ? 12.238  -56.545 -150.518 1.00 55.78  ? 345 TRP A CD1 1 
ATOM 2432 C CD2 . TRP A 1 345 ? 12.719  -56.968 -152.656 1.00 60.42  ? 345 TRP A CD2 1 
ATOM 2433 N NE1 . TRP A 1 345 ? 11.073  -56.902 -151.146 1.00 62.80  ? 345 TRP A NE1 1 
ATOM 2434 C CE2 . TRP A 1 345 ? 11.344  -57.168 -152.461 1.00 60.94  ? 345 TRP A CE2 1 
ATOM 2435 C CE3 . TRP A 1 345 ? 13.256  -57.176 -153.926 1.00 56.16  ? 345 TRP A CE3 1 
ATOM 2436 C CZ2 . TRP A 1 345 ? 10.501  -57.565 -153.487 1.00 58.02  ? 345 TRP A CZ2 1 
ATOM 2437 C CZ3 . TRP A 1 345 ? 12.418  -57.569 -154.940 1.00 50.56  ? 345 TRP A CZ3 1 
ATOM 2438 C CH2 . TRP A 1 345 ? 11.056  -57.759 -154.717 1.00 52.92  ? 345 TRP A CH2 1 
ATOM 2439 N N   . ILE A 1 346 ? 17.793  -56.989 -151.670 1.00 52.72  ? 346 ILE A N   1 
ATOM 2440 C CA  . ILE A 1 346 ? 19.188  -56.608 -151.480 1.00 54.03  ? 346 ILE A CA  1 
ATOM 2441 C C   . ILE A 1 346 ? 19.279  -55.214 -150.883 1.00 51.86  ? 346 ILE A C   1 
ATOM 2442 O O   . ILE A 1 346 ? 20.051  -54.973 -149.946 1.00 55.33  ? 346 ILE A O   1 
ATOM 2443 C CB  . ILE A 1 346 ? 19.955  -56.696 -152.807 1.00 50.90  ? 346 ILE A CB  1 
ATOM 2444 C CG1 . ILE A 1 346 ? 19.963  -58.127 -153.325 1.00 52.86  ? 346 ILE A CG1 1 
ATOM 2445 C CG2 . ILE A 1 346 ? 21.368  -56.199 -152.629 1.00 53.79  ? 346 ILE A CG2 1 
ATOM 2446 C CD1 . ILE A 1 346 ? 20.613  -58.264 -154.669 1.00 60.34  ? 346 ILE A CD1 1 
ATOM 2447 N N   . ASP A 1 347 ? 18.492  -54.278 -151.410 1.00 54.34  ? 347 ASP A N   1 
ATOM 2448 C CA  . ASP A 1 347 ? 18.586  -52.901 -150.947 1.00 62.33  ? 347 ASP A CA  1 
ATOM 2449 C C   . ASP A 1 347 ? 18.206  -52.788 -149.479 1.00 69.22  ? 347 ASP A C   1 
ATOM 2450 O O   . ASP A 1 347 ? 18.767  -51.967 -148.754 1.00 79.95  ? 347 ASP A O   1 
ATOM 2451 C CB  . ASP A 1 347 ? 17.743  -51.984 -151.841 1.00 68.47  ? 347 ASP A CB  1 
ATOM 2452 C CG  . ASP A 1 347 ? 16.245  -52.061 -151.566 1.00 73.99  ? 347 ASP A CG  1 
ATOM 2453 O OD1 . ASP A 1 347 ? 15.807  -51.997 -150.401 1.00 78.37  ? 347 ASP A OD1 1 
ATOM 2454 O OD2 . ASP A 1 347 ? 15.486  -52.187 -152.549 1.00 71.20  ? 347 ASP A OD2 1 
ATOM 2455 N N   . ILE A 1 348 ? 17.271  -53.617 -149.017 1.00 61.38  ? 348 ILE A N   1 
ATOM 2456 C CA  . ILE A 1 348 ? 16.891  -53.585 -147.609 1.00 52.08  ? 348 ILE A CA  1 
ATOM 2457 C C   . ILE A 1 348 ? 18.061  -54.008 -146.730 1.00 59.74  ? 348 ILE A C   1 
ATOM 2458 O O   . ILE A 1 348 ? 18.365  -53.362 -145.721 1.00 68.99  ? 348 ILE A O   1 
ATOM 2459 C CB  . ILE A 1 348 ? 15.657  -54.467 -147.365 1.00 42.69  ? 348 ILE A CB  1 
ATOM 2460 C CG1 . ILE A 1 348 ? 14.399  -53.746 -147.833 1.00 53.10  ? 348 ILE A CG1 1 
ATOM 2461 C CG2 . ILE A 1 348 ? 15.542  -54.818 -145.904 1.00 44.60  ? 348 ILE A CG2 1 
ATOM 2462 C CD1 . ILE A 1 348 ? 13.133  -54.509 -147.563 1.00 59.21  ? 348 ILE A CD1 1 
ATOM 2463 N N   . VAL A 1 349 ? 18.742  -55.091 -147.104 1.00 38.69  ? 349 VAL A N   1 
ATOM 2464 C CA  . VAL A 1 349 ? 19.862  -55.575 -146.301 1.00 34.16  ? 349 VAL A CA  1 
ATOM 2465 C C   . VAL A 1 349 ? 20.991  -54.554 -146.298 1.00 51.23  ? 349 VAL A C   1 
ATOM 2466 O O   . VAL A 1 349 ? 21.568  -54.235 -145.249 1.00 65.07  ? 349 VAL A O   1 
ATOM 2467 C CB  . VAL A 1 349 ? 20.343  -56.939 -146.820 1.00 25.34  ? 349 VAL A CB  1 
ATOM 2468 C CG1 . VAL A 1 349 ? 21.581  -57.370 -146.078 1.00 34.91  ? 349 VAL A CG1 1 
ATOM 2469 C CG2 . VAL A 1 349 ? 19.254  -57.970 -146.672 1.00 47.00  ? 349 VAL A CG2 1 
ATOM 2470 N N   . ARG A 1 350 ? 21.320  -54.024 -147.476 1.00 52.58  ? 350 ARG A N   1 
ATOM 2471 C CA  . ARG A 1 350 ? 22.385  -53.035 -147.556 1.00 46.44  ? 350 ARG A CA  1 
ATOM 2472 C C   . ARG A 1 350 ? 22.029  -51.780 -146.778 1.00 51.23  ? 350 ARG A C   1 
ATOM 2473 O O   . ARG A 1 350 ? 22.887  -51.189 -146.119 1.00 60.50  ? 350 ARG A O   1 
ATOM 2474 C CB  . ARG A 1 350 ? 22.681  -52.693 -149.010 1.00 50.16  ? 350 ARG A CB  1 
ATOM 2475 C CG  . ARG A 1 350 ? 24.083  -52.203 -149.240 1.00 40.38  ? 350 ARG A CG  1 
ATOM 2476 C CD  . ARG A 1 350 ? 24.269  -51.802 -150.680 1.00 52.90  ? 350 ARG A CD  1 
ATOM 2477 N NE  . ARG A 1 350 ? 25.311  -50.799 -150.834 1.00 50.39  ? 350 ARG A NE  1 
ATOM 2478 C CZ  . ARG A 1 350 ? 25.398  -49.972 -151.864 1.00 58.28  ? 350 ARG A CZ  1 
ATOM 2479 N NH1 . ARG A 1 350 ? 24.516  -49.999 -152.847 1.00 57.15  ? 350 ARG A NH1 1 
ATOM 2480 N NH2 . ARG A 1 350 ? 26.397  -49.098 -151.910 1.00 64.23  ? 350 ARG A NH2 1 
ATOM 2481 N N   . GLY A 1 351 ? 20.768  -51.358 -146.837 1.00 54.63  ? 351 GLY A N   1 
ATOM 2482 C CA  . GLY A 1 351 ? 20.357  -50.188 -146.087 1.00 55.91  ? 351 GLY A CA  1 
ATOM 2483 C C   . GLY A 1 351 ? 20.417  -50.409 -144.592 1.00 59.18  ? 351 GLY A C   1 
ATOM 2484 O O   . GLY A 1 351 ? 20.783  -49.506 -143.845 1.00 68.71  ? 351 GLY A O   1 
ATOM 2485 N N   . VAL A 1 352 ? 20.061  -51.607 -144.132 1.00 47.18  ? 352 VAL A N   1 
ATOM 2486 C CA  . VAL A 1 352 ? 20.157  -51.898 -142.705 1.00 43.21  ? 352 VAL A CA  1 
ATOM 2487 C C   . VAL A 1 352 ? 21.611  -51.859 -142.253 1.00 54.66  ? 352 VAL A C   1 
ATOM 2488 O O   . VAL A 1 352 ? 21.942  -51.280 -141.206 1.00 67.14  ? 352 VAL A O   1 
ATOM 2489 C CB  . VAL A 1 352 ? 19.501  -53.254 -142.394 1.00 41.83  ? 352 VAL A CB  1 
ATOM 2490 C CG1 . VAL A 1 352 ? 19.882  -53.711 -141.009 1.00 52.84  ? 352 VAL A CG1 1 
ATOM 2491 C CG2 . VAL A 1 352 ? 18.001  -53.143 -142.513 1.00 47.47  ? 352 VAL A CG2 1 
ATOM 2492 N N   . ASP A 1 353 ? 22.504  -52.469 -143.035 1.00 57.96  ? 353 ASP A N   1 
ATOM 2493 C CA  . ASP A 1 353 ? 23.919  -52.414 -142.691 1.00 58.39  ? 353 ASP A CA  1 
ATOM 2494 C C   . ASP A 1 353 ? 24.422  -50.980 -142.682 1.00 67.55  ? 353 ASP A C   1 
ATOM 2495 O O   . ASP A 1 353 ? 25.154  -50.575 -141.771 1.00 75.53  ? 353 ASP A O   1 
ATOM 2496 C CB  . ASP A 1 353 ? 24.736  -53.256 -143.664 1.00 55.95  ? 353 ASP A CB  1 
ATOM 2497 C CG  . ASP A 1 353 ? 24.503  -54.735 -143.480 1.00 72.18  ? 353 ASP A CG  1 
ATOM 2498 O OD1 . ASP A 1 353 ? 23.945  -55.123 -142.435 1.00 75.57  ? 353 ASP A OD1 1 
ATOM 2499 O OD2 . ASP A 1 353 ? 24.880  -55.515 -144.376 1.00 81.81  ? 353 ASP A OD2 1 
ATOM 2500 N N   . TRP A 1 354 ? 24.025  -50.189 -143.678 1.00 63.08  ? 354 TRP A N   1 
ATOM 2501 C CA  . TRP A 1 354 ? 24.447  -48.797 -143.731 1.00 58.87  ? 354 TRP A CA  1 
ATOM 2502 C C   . TRP A 1 354 ? 23.900  -48.013 -142.553 1.00 56.68  ? 354 TRP A C   1 
ATOM 2503 O O   . TRP A 1 354 ? 24.567  -47.117 -142.035 1.00 65.66  ? 354 TRP A O   1 
ATOM 2504 C CB  . TRP A 1 354 ? 23.998  -48.153 -145.037 1.00 58.61  ? 354 TRP A CB  1 
ATOM 2505 C CG  . TRP A 1 354 ? 24.089  -46.671 -145.005 1.00 58.26  ? 354 TRP A CG  1 
ATOM 2506 C CD1 . TRP A 1 354 ? 25.162  -45.912 -145.347 1.00 62.02  ? 354 TRP A CD1 1 
ATOM 2507 C CD2 . TRP A 1 354 ? 23.070  -45.761 -144.590 1.00 56.97  ? 354 TRP A CD2 1 
ATOM 2508 N NE1 . TRP A 1 354 ? 24.874  -44.583 -145.180 1.00 62.30  ? 354 TRP A NE1 1 
ATOM 2509 C CE2 . TRP A 1 354 ? 23.593  -44.466 -144.714 1.00 57.58  ? 354 TRP A CE2 1 
ATOM 2510 C CE3 . TRP A 1 354 ? 21.763  -45.917 -144.129 1.00 59.27  ? 354 TRP A CE3 1 
ATOM 2511 C CZ2 . TRP A 1 354 ? 22.859  -43.335 -144.392 1.00 64.12  ? 354 TRP A CZ2 1 
ATOM 2512 C CZ3 . TRP A 1 354 ? 21.036  -44.794 -143.811 1.00 58.10  ? 354 TRP A CZ3 1 
ATOM 2513 C CH2 . TRP A 1 354 ? 21.584  -43.520 -143.945 1.00 64.92  ? 354 TRP A CH2 1 
ATOM 2514 N N   . LEU A 1 355 ? 22.689  -48.328 -142.123 1.00 50.16  ? 355 LEU A N   1 
ATOM 2515 C CA  . LEU A 1 355 ? 22.165  -47.504 -141.013 1.00 54.70  ? 355 LEU A CA  1 
ATOM 2516 C C   . LEU A 1 355 ? 23.105  -47.749 -139.839 1.00 58.52  ? 355 LEU A C   1 
ATOM 2517 O O   . LEU A 1 355 ? 23.550  -46.779 -139.217 1.00 62.11  ? 355 LEU A O   1 
ATOM 2518 C CB  . LEU A 1 355 ? 20.724  -47.842 -140.647 1.00 46.34  ? 355 LEU A CB  1 
ATOM 2519 C CG  . LEU A 1 355 ? 19.931  -46.750 -139.930 1.00 39.22  ? 355 LEU A CG  1 
ATOM 2520 C CD1 . LEU A 1 355 ? 20.480  -45.377 -140.251 1.00 51.43  ? 355 LEU A CD1 1 
ATOM 2521 C CD2 . LEU A 1 355 ? 18.486  -46.856 -140.360 1.00 48.49  ? 355 LEU A CD2 1 
ATOM 2522 N N   . GLU A 1 356 ? 23.398  -49.013 -139.569 1.00 56.81  ? 356 GLU A N   1 
ATOM 2523 C CA  . GLU A 1 356 ? 24.260  -49.328 -138.418 1.00 55.28  ? 356 GLU A CA  1 
ATOM 2524 C C   . GLU A 1 356 ? 25.548  -48.539 -138.595 1.00 60.36  ? 356 GLU A C   1 
ATOM 2525 O O   . GLU A 1 356 ? 25.904  -47.735 -137.721 1.00 72.19  ? 356 GLU A O   1 
ATOM 2526 C CB  . GLU A 1 356 ? 24.512  -50.803 -138.356 1.00 30.00  ? 356 GLU A CB  1 
ATOM 2527 N N   . SER A 1 357 ? 26.213  -48.737 -139.724 1.00 52.74  ? 357 SER A N   1 
ATOM 2528 C CA  . SER A 1 357 ? 27.505  -48.051 -139.939 1.00 55.53  ? 357 SER A CA  1 
ATOM 2529 C C   . SER A 1 357 ? 27.310  -46.566 -139.670 1.00 58.45  ? 357 SER A C   1 
ATOM 2530 O O   . SER A 1 357 ? 28.253  -45.933 -139.194 1.00 68.21  ? 357 SER A O   1 
ATOM 2531 C CB  . SER A 1 357 ? 28.010  -48.251 -141.316 1.00 53.53  ? 357 SER A CB  1 
ATOM 2532 O OG  . SER A 1 357 ? 28.383  -47.010 -141.892 1.00 54.85  ? 357 SER A OG  1 
ATOM 2533 N N   . ASP A 1 358 ? 26.136  -46.031 -139.971 1.00 55.83  ? 358 ASP A N   1 
ATOM 2534 C CA  . ASP A 1 358 ? 26.006  -44.592 -139.791 1.00 57.99  ? 358 ASP A CA  1 
ATOM 2535 C C   . ASP A 1 358 ? 25.726  -44.240 -138.340 1.00 61.63  ? 358 ASP A C   1 
ATOM 2536 O O   . ASP A 1 358 ? 26.247  -43.245 -137.830 1.00 64.20  ? 358 ASP A O   1 
ATOM 2537 C CB  . ASP A 1 358 ? 24.900  -44.050 -140.689 1.00 59.42  ? 358 ASP A CB  1 
ATOM 2538 C CG  . ASP A 1 358 ? 24.984  -42.558 -140.867 1.00 68.52  ? 358 ASP A CG  1 
ATOM 2539 O OD1 . ASP A 1 358 ? 26.070  -41.996 -140.630 1.00 79.66  ? 358 ASP A OD1 1 
ATOM 2540 O OD2 . ASP A 1 358 ? 23.969  -41.941 -141.244 1.00 69.81  ? 358 ASP A OD2 1 
ATOM 2541 N N   . LEU A 1 359 ? 24.897  -45.035 -137.663 1.00 55.85  ? 359 LEU A N   1 
ATOM 2542 C CA  . LEU A 1 359 ? 24.682  -44.809 -136.240 1.00 52.84  ? 359 LEU A CA  1 
ATOM 2543 C C   . LEU A 1 359 ? 25.985  -44.959 -135.472 1.00 54.30  ? 359 LEU A C   1 
ATOM 2544 O O   . LEU A 1 359 ? 26.298  -44.142 -134.595 1.00 56.79  ? 359 LEU A O   1 
ATOM 2545 C CB  . LEU A 1 359 ? 23.631  -45.778 -135.708 1.00 40.53  ? 359 LEU A CB  1 
ATOM 2546 C CG  . LEU A 1 359 ? 22.177  -45.419 -135.991 1.00 38.76  ? 359 LEU A CG  1 
ATOM 2547 C CD1 . LEU A 1 359 ? 21.306  -46.629 -135.797 1.00 44.08  ? 359 LEU A CD1 1 
ATOM 2548 C CD2 . LEU A 1 359 ? 21.739  -44.316 -135.070 1.00 52.04  ? 359 LEU A CD2 1 
ATOM 2549 N N   . LYS A 1 360 ? 26.767  -45.988 -135.801 1.00 53.10  ? 360 LYS A N   1 
ATOM 2550 C CA  . LYS A 1 360 ? 28.051  -46.175 -135.141 1.00 52.73  ? 360 LYS A CA  1 
ATOM 2551 C C   . LYS A 1 360 ? 28.959  -44.981 -135.375 1.00 57.42  ? 360 LYS A C   1 
ATOM 2552 O O   . LYS A 1 360 ? 29.585  -44.474 -134.442 1.00 67.74  ? 360 LYS A O   1 
ATOM 2553 C CB  . LYS A 1 360 ? 28.719  -47.456 -135.635 1.00 51.42  ? 360 LYS A CB  1 
ATOM 2554 C CG  . LYS A 1 360 ? 28.349  -48.684 -134.843 1.00 55.03  ? 360 LYS A CG  1 
ATOM 2555 C CD  . LYS A 1 360 ? 29.375  -49.779 -135.026 1.00 55.22  ? 360 LYS A CD  1 
ATOM 2556 C CE  . LYS A 1 360 ? 28.715  -51.095 -135.367 1.00 62.81  ? 360 LYS A CE  1 
ATOM 2557 N NZ  . LYS A 1 360 ? 29.720  -52.168 -135.575 1.00 65.32  ? 360 LYS A NZ  1 
ATOM 2558 N N   . THR A 1 361 ? 29.033  -44.506 -136.618 1.00 55.29  ? 361 THR A N   1 
ATOM 2559 C CA  . THR A 1 361 ? 29.917  -43.389 -136.925 1.00 58.95  ? 361 THR A CA  1 
ATOM 2560 C C   . THR A 1 361 ? 29.482  -42.118 -136.208 1.00 62.15  ? 361 THR A C   1 
ATOM 2561 O O   . THR A 1 361 ? 30.316  -41.400 -135.645 1.00 70.65  ? 361 THR A O   1 
ATOM 2562 C CB  . THR A 1 361 ? 29.972  -43.161 -138.432 1.00 57.76  ? 361 THR A CB  1 
ATOM 2563 O OG1 . THR A 1 361 ? 30.604  -44.282 -139.059 1.00 60.49  ? 361 THR A OG1 1 
ATOM 2564 C CG2 . THR A 1 361 ? 30.758  -41.911 -138.751 1.00 66.92  ? 361 THR A CG2 1 
ATOM 2565 N N   . SER A 1 362 ? 28.181  -41.825 -136.204 1.00 49.11  ? 362 SER A N   1 
ATOM 2566 C CA  . SER A 1 362 ? 27.709  -40.604 -135.561 1.00 52.79  ? 362 SER A CA  1 
ATOM 2567 C C   . SER A 1 362 ? 27.937  -40.644 -134.056 1.00 59.23  ? 362 SER A C   1 
ATOM 2568 O O   . SER A 1 362 ? 28.414  -39.666 -133.464 1.00 59.44  ? 362 SER A O   1 
ATOM 2569 C CB  . SER A 1 362 ? 26.231  -40.385 -135.877 1.00 55.72  ? 362 SER A CB  1 
ATOM 2570 O OG  . SER A 1 362 ? 26.072  -39.729 -137.119 1.00 59.70  ? 362 SER A OG  1 
ATOM 2571 N N   . LEU A 1 363 ? 27.624  -41.769 -133.414 1.00 63.39  ? 363 LEU A N   1 
ATOM 2572 C CA  . LEU A 1 363 ? 27.854  -41.843 -131.978 1.00 60.99  ? 363 LEU A CA  1 
ATOM 2573 C C   . LEU A 1 363 ? 29.339  -41.860 -131.645 1.00 62.26  ? 363 LEU A C   1 
ATOM 2574 O O   . LEU A 1 363 ? 29.739  -41.312 -130.615 1.00 60.12  ? 363 LEU A O   1 
ATOM 2575 C CB  . LEU A 1 363 ? 27.155  -43.058 -131.370 1.00 62.09  ? 363 LEU A CB  1 
ATOM 2576 C CG  . LEU A 1 363 ? 25.639  -43.046 -131.142 1.00 53.89  ? 363 LEU A CG  1 
ATOM 2577 C CD1 . LEU A 1 363 ? 25.333  -42.323 -129.854 1.00 52.77  ? 363 LEU A CD1 1 
ATOM 2578 C CD2 . LEU A 1 363 ? 24.860  -42.425 -132.271 1.00 53.78  ? 363 LEU A CD2 1 
ATOM 2579 N N   . ARG A 1 364 ? 30.173  -42.475 -132.484 1.00 59.79  ? 364 ARG A N   1 
ATOM 2580 C CA  . ARG A 1 364 ? 31.609  -42.415 -132.247 1.00 59.19  ? 364 ARG A CA  1 
ATOM 2581 C C   . ARG A 1 364 ? 32.110  -40.986 -132.365 1.00 65.74  ? 364 ARG A C   1 
ATOM 2582 O O   . ARG A 1 364 ? 32.973  -40.556 -131.593 1.00 78.24  ? 364 ARG A O   1 
ATOM 2583 C CB  . ARG A 1 364 ? 32.341  -43.341 -133.221 1.00 63.33  ? 364 ARG A CB  1 
ATOM 2584 C CG  . ARG A 1 364 ? 33.604  -42.763 -133.836 1.00 59.23  ? 364 ARG A CG  1 
ATOM 2585 C CD  . ARG A 1 364 ? 34.159  -43.672 -134.928 1.00 63.73  ? 364 ARG A CD  1 
ATOM 2586 N NE  . ARG A 1 364 ? 34.967  -44.759 -134.383 1.00 79.69  ? 364 ARG A NE  1 
ATOM 2587 C CZ  . ARG A 1 364 ? 35.497  -45.740 -135.103 1.00 74.80  ? 364 ARG A CZ  1 
ATOM 2588 N NH1 . ARG A 1 364 ? 35.327  -45.808 -136.413 1.00 68.35  ? 364 ARG A NH1 1 
ATOM 2589 N NH2 . ARG A 1 364 ? 36.228  -46.670 -134.494 1.00 60.67  ? 364 ARG A NH2 1 
ATOM 2590 N N   . ASP A 1 365 ? 31.563  -40.229 -133.316 1.00 69.75  ? 365 ASP A N   1 
ATOM 2591 C CA  . ASP A 1 365 ? 31.922  -38.823 -133.444 1.00 75.07  ? 365 ASP A CA  1 
ATOM 2592 C C   . ASP A 1 365 ? 31.531  -38.045 -132.196 1.00 75.80  ? 365 ASP A C   1 
ATOM 2593 O O   . ASP A 1 365 ? 32.300  -37.209 -131.710 1.00 83.26  ? 365 ASP A O   1 
ATOM 2594 C CB  . ASP A 1 365 ? 31.245  -38.229 -134.678 1.00 80.37  ? 365 ASP A CB  1 
ATOM 2595 C CG  . ASP A 1 365 ? 31.833  -36.897 -135.083 1.00 86.81  ? 365 ASP A CG  1 
ATOM 2596 O OD1 . ASP A 1 365 ? 32.536  -36.272 -134.264 1.00 89.39  ? 365 ASP A OD1 1 
ATOM 2597 O OD2 . ASP A 1 365 ? 31.605  -36.478 -136.237 1.00 90.65  ? 365 ASP A OD2 1 
ATOM 2598 N N   . LEU A 1 366 ? 30.337  -38.301 -131.664 1.00 58.63  ? 366 LEU A N   1 
ATOM 2599 C CA  . LEU A 1 366 ? 29.930  -37.607 -130.446 1.00 53.91  ? 366 LEU A CA  1 
ATOM 2600 C C   . LEU A 1 366 ? 30.806  -37.996 -129.261 1.00 62.23  ? 366 LEU A C   1 
ATOM 2601 O O   . LEU A 1 366 ? 31.217  -37.134 -128.478 1.00 66.55  ? 366 LEU A O   1 
ATOM 2602 C CB  . LEU A 1 366 ? 28.465  -37.892 -130.130 1.00 58.48  ? 366 LEU A CB  1 
ATOM 2603 C CG  . LEU A 1 366 ? 28.050  -37.574 -128.694 1.00 47.20  ? 366 LEU A CG  1 
ATOM 2604 C CD1 . LEU A 1 366 ? 28.095  -36.085 -128.454 1.00 55.78  ? 366 LEU A CD1 1 
ATOM 2605 C CD2 . LEU A 1 366 ? 26.672  -38.110 -128.399 1.00 55.02  ? 366 LEU A CD2 1 
ATOM 2606 N N   . LEU A 1 367 ? 31.108  -39.282 -129.115 1.00 56.23  ? 367 LEU A N   1 
ATOM 2607 C CA  . LEU A 1 367 ? 31.758  -39.794 -127.918 1.00 46.47  ? 367 LEU A CA  1 
ATOM 2608 C C   . LEU A 1 367 ? 33.275  -39.723 -127.967 1.00 51.98  ? 367 LEU A C   1 
ATOM 2609 O O   . LEU A 1 367 ? 33.922  -40.009 -126.955 1.00 62.75  ? 367 LEU A O   1 
ATOM 2610 C CB  . LEU A 1 367 ? 31.335  -41.243 -127.674 1.00 42.84  ? 367 LEU A CB  1 
ATOM 2611 C CG  . LEU A 1 367 ? 29.865  -41.481 -127.351 1.00 40.24  ? 367 LEU A CG  1 
ATOM 2612 C CD1 . LEU A 1 367 ? 29.533  -42.941 -127.506 1.00 49.22  ? 367 LEU A CD1 1 
ATOM 2613 C CD2 . LEU A 1 367 ? 29.563  -41.024 -125.950 1.00 50.00  ? 367 LEU A CD2 1 
ATOM 2614 N N   . ILE A 1 368 ? 33.863  -39.369 -129.104 1.00 48.76  ? 368 ILE A N   1 
ATOM 2615 C CA  . ILE A 1 368 ? 35.313  -39.260 -129.184 1.00 48.71  ? 368 ILE A CA  1 
ATOM 2616 C C   . ILE A 1 368 ? 35.771  -37.826 -128.983 1.00 59.18  ? 368 ILE A C   1 
ATOM 2617 O O   . ILE A 1 368 ? 36.719  -37.570 -128.239 1.00 70.21  ? 368 ILE A O   1 
ATOM 2618 C CB  . ILE A 1 368 ? 35.805  -39.820 -130.531 1.00 52.13  ? 368 ILE A CB  1 
ATOM 2619 C CG1 . ILE A 1 368 ? 35.839  -41.343 -130.491 1.00 52.75  ? 368 ILE A CG1 1 
ATOM 2620 C CG2 . ILE A 1 368 ? 37.178  -39.276 -130.871 1.00 60.67  ? 368 ILE A CG2 1 
ATOM 2621 C CD1 . ILE A 1 368 ? 36.459  -41.948 -131.717 1.00 59.20  ? 368 ILE A CD1 1 
ATOM 2622 N N   . ASN A 1 369 ? 35.099  -36.880 -129.610 1.00 64.23  ? 369 ASN A N   1 
ATOM 2623 C CA  . ASN A 1 369 ? 35.524  -35.489 -129.618 1.00 68.81  ? 369 ASN A CA  1 
ATOM 2624 C C   . ASN A 1 369 ? 35.315  -34.795 -128.310 1.00 69.80  ? 369 ASN A C   1 
ATOM 2625 O O   . ASN A 1 369 ? 35.451  -33.572 -128.273 1.00 75.59  ? 369 ASN A O   1 
ATOM 2626 C CB  . ASN A 1 369 ? 34.786  -34.743 -130.725 1.00 73.65  ? 369 ASN A CB  1 
ATOM 2627 C CG  . ASN A 1 369 ? 35.162  -35.239 -132.101 1.00 82.92  ? 369 ASN A CG  1 
ATOM 2628 O OD1 . ASN A 1 369 ? 36.164  -34.813 -132.674 1.00 84.54  ? 369 ASN A OD1 1 
ATOM 2629 N ND2 . ASN A 1 369 ? 34.364  -36.151 -132.639 1.00 85.49  ? 369 ASN A ND2 1 
ATOM 2630 N N   . GLN A 1 370 ? 34.988  -35.493 -127.226 1.00 64.18  ? 370 GLN A N   1 
ATOM 2631 C CA  . GLN A 1 370 ? 34.795  -34.851 -125.928 1.00 65.24  ? 370 GLN A CA  1 
ATOM 2632 C C   . GLN A 1 370 ? 36.129  -34.797 -125.185 1.00 70.67  ? 370 GLN A C   1 
ATOM 2633 O O   . GLN A 1 370 ? 36.309  -35.367 -124.109 1.00 79.86  ? 370 GLN A O   1 
ATOM 2634 C CB  . GLN A 1 370 ? 33.737  -35.594 -125.124 1.00 67.48  ? 370 GLN A CB  1 
ATOM 2635 C CG  . GLN A 1 370 ? 32.334  -35.498 -125.695 1.00 71.37  ? 370 GLN A CG  1 
ATOM 2636 C CD  . GLN A 1 370 ? 31.690  -34.141 -125.487 1.00 76.48  ? 370 GLN A CD  1 
ATOM 2637 O OE1 . GLN A 1 370 ? 30.596  -33.884 -125.986 1.00 73.77  ? 370 GLN A OE1 1 
ATOM 2638 N NE2 . GLN A 1 370 ? 32.350  -33.277 -124.729 1.00 79.90  ? 370 GLN A NE2 1 
ATOM 2639 N N   . LYS A 1 371 ? 37.086  -34.091 -125.791 1.00 70.11  ? 371 LYS A N   1 
ATOM 2640 C CA  . LYS A 1 371 ? 38.406  -33.975 -125.182 1.00 68.17  ? 371 LYS A CA  1 
ATOM 2641 C C   . LYS A 1 371 ? 38.402  -33.072 -123.962 1.00 62.20  ? 371 LYS A C   1 
ATOM 2642 O O   . LYS A 1 371 ? 39.061  -33.381 -122.966 1.00 65.10  ? 371 LYS A O   1 
ATOM 2643 C CB  . LYS A 1 371 ? 39.424  -33.447 -126.190 1.00 66.03  ? 371 LYS A CB  1 
ATOM 2644 C CG  . LYS A 1 371 ? 40.863  -33.702 -125.777 1.00 67.31  ? 371 LYS A CG  1 
ATOM 2645 C CD  . LYS A 1 371 ? 41.834  -32.813 -126.537 1.00 71.79  ? 371 LYS A CD  1 
ATOM 2646 C CE  . LYS A 1 371 ? 43.177  -32.731 -125.830 1.00 69.19  ? 371 LYS A CE  1 
ATOM 2647 N NZ  . LYS A 1 371 ? 44.297  -33.171 -126.705 1.00 63.35  ? 371 LYS A NZ  1 
ATOM 2648 N N   . GLY A 1 372 ? 37.684  -31.958 -124.020 1.00 62.05  ? 372 GLY A N   1 
ATOM 2649 C CA  . GLY A 1 372 ? 37.694  -31.006 -122.931 1.00 69.68  ? 372 GLY A CA  1 
ATOM 2650 C C   . GLY A 1 372 ? 37.152  -31.570 -121.638 1.00 66.28  ? 372 GLY A C   1 
ATOM 2651 O O   . GLY A 1 372 ? 37.716  -31.337 -120.568 1.00 66.26  ? 372 GLY A O   1 
ATOM 2652 N N   . GLY A 1 373 ? 36.062  -32.318 -121.724 1.00 71.77  ? 373 GLY A N   1 
ATOM 2653 C CA  . GLY A 1 373 ? 35.424  -32.815 -120.523 1.00 70.77  ? 373 GLY A CA  1 
ATOM 2654 C C   . GLY A 1 373 ? 34.784  -34.160 -120.764 1.00 65.42  ? 373 GLY A C   1 
ATOM 2655 O O   . GLY A 1 373 ? 35.343  -35.034 -121.431 1.00 76.83  ? 373 GLY A O   1 
ATOM 2656 N N   . LYS A 1 374 ? 33.585  -34.304 -120.219 1.00 48.52  ? 374 LYS A N   1 
ATOM 2657 C CA  . LYS A 1 374 ? 32.924  -35.593 -120.119 1.00 56.07  ? 374 LYS A CA  1 
ATOM 2658 C C   . LYS A 1 374 ? 31.462  -35.416 -120.486 1.00 61.99  ? 374 LYS A C   1 
ATOM 2659 O O   . LYS A 1 374 ? 30.938  -34.300 -120.490 1.00 71.27  ? 374 LYS A O   1 
ATOM 2660 C CB  . LYS A 1 374 ? 33.057  -36.161 -118.705 1.00 64.21  ? 374 LYS A CB  1 
ATOM 2661 C CG  . LYS A 1 374 ? 32.563  -35.197 -117.635 1.00 62.73  ? 374 LYS A CG  1 
ATOM 2662 C CD  . LYS A 1 374 ? 32.371  -35.871 -116.290 1.00 63.40  ? 374 LYS A CD  1 
ATOM 2663 C CE  . LYS A 1 374 ? 33.570  -36.717 -115.918 1.00 61.61  ? 374 LYS A CE  1 
ATOM 2664 N NZ  . LYS A 1 374 ? 33.457  -37.242 -114.532 1.00 68.34  ? 374 LYS A NZ  1 
ATOM 2665 N N   . ILE A 1 375 ? 30.813  -36.530 -120.808 1.00 56.68  ? 375 ILE A N   1 
ATOM 2666 C CA  . ILE A 1 375 ? 29.364  -36.551 -120.954 1.00 47.58  ? 375 ILE A CA  1 
ATOM 2667 C C   . ILE A 1 375 ? 28.781  -37.180 -119.703 1.00 56.99  ? 375 ILE A C   1 
ATOM 2668 O O   . ILE A 1 375 ? 28.802  -38.404 -119.545 1.00 70.02  ? 375 ILE A O   1 
ATOM 2669 C CB  . ILE A 1 375 ? 28.928  -37.320 -122.209 1.00 46.42  ? 375 ILE A CB  1 
ATOM 2670 C CG1 . ILE A 1 375 ? 29.888  -37.043 -123.358 1.00 55.88  ? 375 ILE A CG1 1 
ATOM 2671 C CG2 . ILE A 1 375 ? 27.526  -36.935 -122.602 1.00 49.18  ? 375 ILE A CG2 1 
ATOM 2672 C CD1 . ILE A 1 375 ? 29.437  -37.633 -124.660 1.00 59.28  ? 375 ILE A CD1 1 
ATOM 2673 N N   . THR A 1 376 ? 28.262  -36.351 -118.804 1.00 62.22  ? 376 THR A N   1 
ATOM 2674 C CA  . THR A 1 376 ? 27.796  -36.845 -117.518 1.00 69.49  ? 376 THR A CA  1 
ATOM 2675 C C   . THR A 1 376 ? 26.616  -37.785 -117.709 1.00 71.50  ? 376 THR A C   1 
ATOM 2676 O O   . THR A 1 376 ? 25.847  -37.665 -118.665 1.00 69.45  ? 376 THR A O   1 
ATOM 2677 C CB  . THR A 1 376 ? 27.402  -35.679 -116.618 1.00 68.24  ? 376 THR A CB  1 
ATOM 2678 O OG1 . THR A 1 376 ? 26.723  -34.690 -117.399 1.00 73.36  ? 376 THR A OG1 1 
ATOM 2679 C CG2 . THR A 1 376 ? 28.637  -35.057 -115.997 1.00 59.68  ? 376 THR A CG2 1 
ATOM 2680 N N   . TYR A 1 377 ? 26.473  -38.732 -116.790 1.00 71.63  ? 377 TYR A N   1 
ATOM 2681 C CA  . TYR A 1 377 ? 25.448  -39.756 -116.923 1.00 71.23  ? 377 TYR A CA  1 
ATOM 2682 C C   . TYR A 1 377 ? 24.060  -39.271 -116.539 1.00 69.35  ? 377 TYR A C   1 
ATOM 2683 O O   . TYR A 1 377 ? 23.167  -40.098 -116.345 1.00 76.75  ? 377 TYR A O   1 
ATOM 2684 C CB  . TYR A 1 377 ? 25.807  -40.981 -116.081 1.00 69.39  ? 377 TYR A CB  1 
ATOM 2685 C CG  . TYR A 1 377 ? 25.375  -42.279 -116.716 1.00 66.38  ? 377 TYR A CG  1 
ATOM 2686 C CD1 . TYR A 1 377 ? 26.104  -42.843 -117.744 1.00 63.29  ? 377 TYR A CD1 1 
ATOM 2687 C CD2 . TYR A 1 377 ? 24.220  -42.921 -116.306 1.00 69.83  ? 377 TYR A CD2 1 
ATOM 2688 C CE1 . TYR A 1 377 ? 25.707  -44.019 -118.329 1.00 71.64  ? 377 TYR A CE1 1 
ATOM 2689 C CE2 . TYR A 1 377 ? 23.814  -44.094 -116.889 1.00 69.11  ? 377 TYR A CE2 1 
ATOM 2690 C CZ  . TYR A 1 377 ? 24.561  -44.640 -117.900 1.00 74.10  ? 377 TYR A CZ  1 
ATOM 2691 O OH  . TYR A 1 377 ? 24.160  -45.817 -118.486 1.00 76.72  ? 377 TYR A OH  1 
ATOM 2692 N N   . ASP A 1 378 ? 23.846  -37.970 -116.422 1.00 67.53  ? 378 ASP A N   1 
ATOM 2693 C CA  . ASP A 1 378 ? 22.524  -37.466 -116.086 1.00 72.79  ? 378 ASP A CA  1 
ATOM 2694 C C   . ASP A 1 378 ? 21.653  -37.446 -117.340 1.00 75.73  ? 378 ASP A C   1 
ATOM 2695 O O   . ASP A 1 378 ? 21.997  -38.022 -118.374 1.00 80.18  ? 378 ASP A O   1 
ATOM 2696 C CB  . ASP A 1 378 ? 22.645  -36.116 -115.373 1.00 85.98  ? 378 ASP A CB  1 
ATOM 2697 C CG  . ASP A 1 378 ? 23.055  -34.974 -116.294 1.00 89.08  ? 378 ASP A CG  1 
ATOM 2698 O OD1 . ASP A 1 378 ? 22.774  -35.011 -117.505 1.00 86.18  ? 378 ASP A OD1 1 
ATOM 2699 O OD2 . ASP A 1 378 ? 23.678  -34.018 -115.789 1.00 86.59  ? 378 ASP A OD2 1 
ATOM 2700 N N   . ASP A 1 379 ? 20.499  -36.780 -117.254 1.00 79.65  ? 379 ASP A N   1 
ATOM 2701 C CA  . ASP A 1 379 ? 19.563  -36.768 -118.371 1.00 74.73  ? 379 ASP A CA  1 
ATOM 2702 C C   . ASP A 1 379 ? 20.123  -36.034 -119.578 1.00 76.68  ? 379 ASP A C   1 
ATOM 2703 O O   . ASP A 1 379 ? 19.720  -36.313 -120.711 1.00 81.46  ? 379 ASP A O   1 
ATOM 2704 C CB  . ASP A 1 379 ? 18.245  -36.130 -117.941 1.00 74.67  ? 379 ASP A CB  1 
ATOM 2705 C CG  . ASP A 1 379 ? 17.355  -37.092 -117.195 1.00 82.37  ? 379 ASP A CG  1 
ATOM 2706 O OD1 . ASP A 1 379 ? 17.528  -38.313 -117.372 1.00 84.38  ? 379 ASP A OD1 1 
ATOM 2707 O OD2 . ASP A 1 379 ? 16.486  -36.631 -116.428 1.00 84.15  ? 379 ASP A OD2 1 
ATOM 2708 N N   . THR A 1 380 ? 21.039  -35.092 -119.362 1.00 66.54  ? 380 THR A N   1 
ATOM 2709 C CA  . THR A 1 380 ? 21.570  -34.309 -120.472 1.00 62.08  ? 380 THR A CA  1 
ATOM 2710 C C   . THR A 1 380 ? 22.352  -35.182 -121.445 1.00 64.17  ? 380 THR A C   1 
ATOM 2711 O O   . THR A 1 380 ? 22.189  -35.073 -122.665 1.00 72.16  ? 380 THR A O   1 
ATOM 2712 C CB  . THR A 1 380 ? 22.441  -33.178 -119.935 1.00 60.34  ? 380 THR A CB  1 
ATOM 2713 O OG1 . THR A 1 380 ? 21.608  -32.158 -119.375 1.00 69.57  ? 380 THR A OG1 1 
ATOM 2714 C CG2 . THR A 1 380 ? 23.284  -32.594 -121.032 1.00 65.66  ? 380 THR A CG2 1 
ATOM 2715 N N   . GLY A 1 381 ? 23.213  -36.054 -120.924 1.00 57.65  ? 381 GLY A N   1 
ATOM 2716 C CA  . GLY A 1 381 ? 23.966  -36.932 -121.802 1.00 63.83  ? 381 GLY A CA  1 
ATOM 2717 C C   . GLY A 1 381 ? 23.070  -37.870 -122.584 1.00 60.66  ? 381 GLY A C   1 
ATOM 2718 O O   . GLY A 1 381 ? 23.274  -38.091 -123.782 1.00 67.67  ? 381 GLY A O   1 
ATOM 2719 N N   . ILE A 1 382 ? 22.059  -38.426 -121.921 1.00 51.92  ? 382 ILE A N   1 
ATOM 2720 C CA  . ILE A 1 382 ? 21.124  -39.308 -122.606 1.00 56.46  ? 382 ILE A CA  1 
ATOM 2721 C C   . ILE A 1 382 ? 20.375  -38.546 -123.687 1.00 61.64  ? 382 ILE A C   1 
ATOM 2722 O O   . ILE A 1 382 ? 20.129  -39.071 -124.778 1.00 67.36  ? 382 ILE A O   1 
ATOM 2723 C CB  . ILE A 1 382 ? 20.166  -39.956 -121.595 1.00 56.56  ? 382 ILE A CB  1 
ATOM 2724 C CG1 . ILE A 1 382 ? 20.942  -40.886 -120.667 1.00 55.27  ? 382 ILE A CG1 1 
ATOM 2725 C CG2 . ILE A 1 382 ? 19.080  -40.718 -122.310 1.00 66.37  ? 382 ILE A CG2 1 
ATOM 2726 C CD1 . ILE A 1 382 ? 20.112  -41.457 -119.558 1.00 64.82  ? 382 ILE A CD1 1 
ATOM 2727 N N   . THR A 1 383 ? 20.003  -37.298 -123.407 1.00 52.28  ? 383 THR A N   1 
ATOM 2728 C CA  . THR A 1 383 ? 19.304  -36.503 -124.409 1.00 45.79  ? 383 THR A CA  1 
ATOM 2729 C C   . THR A 1 383 ? 20.193  -36.217 -125.610 1.00 52.79  ? 383 THR A C   1 
ATOM 2730 O O   . THR A 1 383 ? 19.730  -36.270 -126.752 1.00 61.97  ? 383 THR A O   1 
ATOM 2731 C CB  . THR A 1 383 ? 18.805  -35.200 -123.798 1.00 48.25  ? 383 THR A CB  1 
ATOM 2732 O OG1 . THR A 1 383 ? 17.986  -35.494 -122.662 1.00 65.71  ? 383 THR A OG1 1 
ATOM 2733 C CG2 . THR A 1 383 ? 17.991  -34.433 -124.807 1.00 52.86  ? 383 THR A CG2 1 
ATOM 2734 N N   . ARG A 1 384 ? 21.468  -35.907 -125.378 1.00 44.44  ? 384 ARG A N   1 
ATOM 2735 C CA  . ARG A 1 384 ? 22.373  -35.687 -126.502 1.00 42.60  ? 384 ARG A CA  1 
ATOM 2736 C C   . ARG A 1 384 ? 22.522  -36.950 -127.337 1.00 53.15  ? 384 ARG A C   1 
ATOM 2737 O O   . ARG A 1 384 ? 22.507  -36.896 -128.575 1.00 60.59  ? 384 ARG A O   1 
ATOM 2738 C CB  . ARG A 1 384 ? 23.738  -35.223 -126.003 1.00 51.97  ? 384 ARG A CB  1 
ATOM 2739 C CG  . ARG A 1 384 ? 23.699  -33.961 -125.181 1.00 55.36  ? 384 ARG A CG  1 
ATOM 2740 C CD  . ARG A 1 384 ? 24.998  -33.753 -124.435 1.00 50.30  ? 384 ARG A CD  1 
ATOM 2741 N NE  . ARG A 1 384 ? 26.147  -33.792 -125.327 1.00 51.76  ? 384 ARG A NE  1 
ATOM 2742 C CZ  . ARG A 1 384 ? 27.326  -33.259 -125.044 1.00 55.04  ? 384 ARG A CZ  1 
ATOM 2743 N NH1 . ARG A 1 384 ? 27.545  -32.641 -123.897 1.00 52.23  ? 384 ARG A NH1 1 
ATOM 2744 N NH2 . ARG A 1 384 ? 28.309  -33.345 -125.934 1.00 54.61  ? 384 ARG A NH2 1 
ATOM 2745 N N   . ILE A 1 385 ? 22.663  -38.100 -126.677 1.00 55.78  ? 385 ILE A N   1 
ATOM 2746 C CA  . ILE A 1 385 ? 22.790  -39.359 -127.404 1.00 56.62  ? 385 ILE A CA  1 
ATOM 2747 C C   . ILE A 1 385 ? 21.537  -39.630 -128.222 1.00 57.91  ? 385 ILE A C   1 
ATOM 2748 O O   . ILE A 1 385 ? 21.609  -40.042 -129.388 1.00 63.65  ? 385 ILE A O   1 
ATOM 2749 C CB  . ILE A 1 385 ? 23.090  -40.508 -126.427 1.00 51.19  ? 385 ILE A CB  1 
ATOM 2750 C CG1 . ILE A 1 385 ? 24.494  -40.360 -125.852 1.00 51.08  ? 385 ILE A CG1 1 
ATOM 2751 C CG2 . ILE A 1 385 ? 22.938  -41.840 -127.116 1.00 48.00  ? 385 ILE A CG2 1 
ATOM 2752 C CD1 . ILE A 1 385 ? 24.805  -41.347 -124.763 1.00 58.68  ? 385 ILE A CD1 1 
ATOM 2753 N N   . ARG A 1 386 ? 20.366  -39.395 -127.629 1.00 49.96  ? 386 ARG A N   1 
ATOM 2754 C CA  . ARG A 1 386 ? 19.120  -39.602 -128.355 1.00 47.58  ? 386 ARG A CA  1 
ATOM 2755 C C   . ARG A 1 386 ? 19.011  -38.659 -129.540 1.00 50.53  ? 386 ARG A C   1 
ATOM 2756 O O   . ARG A 1 386 ? 18.516  -39.044 -130.603 1.00 63.07  ? 386 ARG A O   1 
ATOM 2757 C CB  . ARG A 1 386 ? 17.929  -39.417 -127.427 1.00 44.28  ? 386 ARG A CB  1 
ATOM 2758 C CG  . ARG A 1 386 ? 16.628  -39.775 -128.086 1.00 50.06  ? 386 ARG A CG  1 
ATOM 2759 C CD  . ARG A 1 386 ? 15.449  -39.402 -127.233 1.00 50.42  ? 386 ARG A CD  1 
ATOM 2760 N NE  . ARG A 1 386 ? 14.326  -38.985 -128.056 1.00 49.64  ? 386 ARG A NE  1 
ATOM 2761 C CZ  . ARG A 1 386 ? 13.448  -38.063 -127.700 1.00 57.88  ? 386 ARG A CZ  1 
ATOM 2762 N NH1 . ARG A 1 386 ? 13.525  -37.455 -126.529 1.00 62.71  ? 386 ARG A NH1 1 
ATOM 2763 N NH2 . ARG A 1 386 ? 12.468  -37.743 -128.539 1.00 61.34  ? 386 ARG A NH2 1 
ATOM 2764 N N   . GLN A 1 387 ? 19.449  -37.414 -129.375 1.00 55.31  ? 387 GLN A N   1 
ATOM 2765 C CA  . GLN A 1 387 ? 19.401  -36.475 -130.486 1.00 56.73  ? 387 GLN A CA  1 
ATOM 2766 C C   . GLN A 1 387 ? 20.294  -36.930 -131.626 1.00 58.80  ? 387 GLN A C   1 
ATOM 2767 O O   . GLN A 1 387 ? 19.925  -36.806 -132.796 1.00 75.25  ? 387 GLN A O   1 
ATOM 2768 C CB  . GLN A 1 387 ? 19.808  -35.080 -130.029 1.00 57.21  ? 387 GLN A CB  1 
ATOM 2769 C CG  . GLN A 1 387 ? 19.616  -34.030 -131.095 1.00 55.17  ? 387 GLN A CG  1 
ATOM 2770 C CD  . GLN A 1 387 ? 20.853  -33.820 -131.927 1.00 60.28  ? 387 GLN A CD  1 
ATOM 2771 O OE1 . GLN A 1 387 ? 21.968  -34.024 -131.459 1.00 63.23  ? 387 GLN A OE1 1 
ATOM 2772 N NE2 . GLN A 1 387 ? 20.664  -33.424 -133.175 1.00 62.79  ? 387 GLN A NE2 1 
ATOM 2773 N N   . VAL A 1 388 ? 21.482  -37.445 -131.310 1.00 48.77  ? 388 VAL A N   1 
ATOM 2774 C CA  . VAL A 1 388 ? 22.361  -37.920 -132.374 1.00 42.87  ? 388 VAL A CA  1 
ATOM 2775 C C   . VAL A 1 388 ? 21.747  -39.128 -133.071 1.00 52.08  ? 388 VAL A C   1 
ATOM 2776 O O   . VAL A 1 388 ? 21.813  -39.258 -134.302 1.00 63.35  ? 388 VAL A O   1 
ATOM 2777 C CB  . VAL A 1 388 ? 23.759  -38.230 -131.819 1.00 45.73  ? 388 VAL A CB  1 
ATOM 2778 C CG1 . VAL A 1 388 ? 24.631  -38.804 -132.903 1.00 50.78  ? 388 VAL A CG1 1 
ATOM 2779 C CG2 . VAL A 1 388 ? 24.383  -36.980 -131.261 1.00 56.38  ? 388 VAL A CG2 1 
ATOM 2780 N N   . ILE A 1 389 ? 21.125  -40.025 -132.303 1.00 49.81  ? 389 ILE A N   1 
ATOM 2781 C CA  . ILE A 1 389 ? 20.456  -41.173 -132.910 1.00 46.50  ? 389 ILE A CA  1 
ATOM 2782 C C   . ILE A 1 389 ? 19.349  -40.711 -133.847 1.00 55.04  ? 389 ILE A C   1 
ATOM 2783 O O   . ILE A 1 389 ? 19.212  -41.209 -134.973 1.00 65.25  ? 389 ILE A O   1 
ATOM 2784 C CB  . ILE A 1 389 ? 19.910  -42.111 -131.821 1.00 45.34  ? 389 ILE A CB  1 
ATOM 2785 C CG1 . ILE A 1 389 ? 21.048  -42.822 -131.104 1.00 52.52  ? 389 ILE A CG1 1 
ATOM 2786 C CG2 . ILE A 1 389 ? 18.976  -43.127 -132.418 1.00 44.55  ? 389 ILE A CG2 1 
ATOM 2787 C CD1 . ILE A 1 389 ? 20.582  -43.674 -129.962 1.00 54.43  ? 389 ILE A CD1 1 
ATOM 2788 N N   . GLU A 1 390 ? 18.541  -39.751 -133.400 1.00 52.16  ? 390 GLU A N   1 
ATOM 2789 C CA  . GLU A 1 390 ? 17.440  -39.276 -134.224 1.00 50.62  ? 390 GLU A CA  1 
ATOM 2790 C C   . GLU A 1 390 ? 17.953  -38.546 -135.455 1.00 53.74  ? 390 GLU A C   1 
ATOM 2791 O O   . GLU A 1 390 ? 17.338  -38.609 -136.521 1.00 70.22  ? 390 GLU A O   1 
ATOM 2792 C CB  . GLU A 1 390 ? 16.521  -38.376 -133.409 1.00 55.20  ? 390 GLU A CB  1 
ATOM 2793 C CG  . GLU A 1 390 ? 15.208  -39.030 -133.051 1.00 62.35  ? 390 GLU A CG  1 
ATOM 2794 C CD  . GLU A 1 390 ? 14.399  -38.204 -132.081 1.00 79.93  ? 390 GLU A CD  1 
ATOM 2795 O OE1 . GLU A 1 390 ? 14.352  -36.972 -132.257 1.00 85.63  ? 390 GLU A OE1 1 
ATOM 2796 O OE2 . GLU A 1 390 ? 13.817  -38.781 -131.140 1.00 80.17  ? 390 GLU A OE2 1 
ATOM 2797 N N   . THR A 1 391 ? 19.074  -37.840 -135.329 1.00 43.04  ? 391 THR A N   1 
ATOM 2798 C CA  . THR A 1 391 ? 19.674  -37.210 -136.498 1.00 43.38  ? 391 THR A CA  1 
ATOM 2799 C C   . THR A 1 391 ? 20.099  -38.250 -137.519 1.00 56.03  ? 391 THR A C   1 
ATOM 2800 O O   . THR A 1 391 ? 19.891  -38.069 -138.723 1.00 74.26  ? 391 THR A O   1 
ATOM 2801 C CB  . THR A 1 391 ? 20.869  -36.357 -136.086 1.00 52.24  ? 391 THR A CB  1 
ATOM 2802 O OG1 . THR A 1 391 ? 20.423  -35.277 -135.259 1.00 71.99  ? 391 THR A OG1 1 
ATOM 2803 C CG2 . THR A 1 391 ? 21.567  -35.801 -137.308 1.00 53.18  ? 391 THR A CG2 1 
ATOM 2804 N N   . SER A 1 392 ? 20.698  -39.349 -137.060 1.00 52.75  ? 392 SER A N   1 
ATOM 2805 C CA  . SER A 1 392 ? 21.079  -40.407 -137.992 1.00 46.28  ? 392 SER A CA  1 
ATOM 2806 C C   . SER A 1 392 ? 19.855  -41.012 -138.667 1.00 53.77  ? 392 SER A C   1 
ATOM 2807 O O   . SER A 1 392 ? 19.858  -41.266 -139.879 1.00 62.73  ? 392 SER A O   1 
ATOM 2808 C CB  . SER A 1 392 ? 21.874  -41.482 -137.264 1.00 48.68  ? 392 SER A CB  1 
ATOM 2809 O OG  . SER A 1 392 ? 23.124  -40.976 -136.839 1.00 61.15  ? 392 SER A OG  1 
ATOM 2810 N N   . LEU A 1 393 ? 18.788  -41.234 -137.903 1.00 52.83  ? 393 LEU A N   1 
ATOM 2811 C CA  . LEU A 1 393 ? 17.582  -41.797 -138.500 1.00 50.73  ? 393 LEU A CA  1 
ATOM 2812 C C   . LEU A 1 393 ? 16.946  -40.823 -139.486 1.00 50.90  ? 393 LEU A C   1 
ATOM 2813 O O   . LEU A 1 393 ? 16.403  -41.239 -140.515 1.00 59.28  ? 393 LEU A O   1 
ATOM 2814 C CB  . LEU A 1 393 ? 16.593  -42.194 -137.411 1.00 44.16  ? 393 LEU A CB  1 
ATOM 2815 C CG  . LEU A 1 393 ? 16.967  -43.495 -136.710 1.00 43.55  ? 393 LEU A CG  1 
ATOM 2816 C CD1 . LEU A 1 393 ? 16.023  -43.773 -135.570 1.00 53.45  ? 393 LEU A CD1 1 
ATOM 2817 C CD2 . LEU A 1 393 ? 16.952  -44.632 -137.698 1.00 44.42  ? 393 LEU A CD2 1 
ATOM 2818 N N   . GLN A 1 394 ? 17.007  -39.525 -139.200 1.00 53.84  ? 394 GLN A N   1 
ATOM 2819 C CA  . GLN A 1 394 ? 16.489  -38.543 -140.143 1.00 53.95  ? 394 GLN A CA  1 
ATOM 2820 C C   . GLN A 1 394 ? 17.344  -38.476 -141.398 1.00 55.45  ? 394 GLN A C   1 
ATOM 2821 O O   . GLN A 1 394 ? 16.825  -38.221 -142.489 1.00 61.43  ? 394 GLN A O   1 
ATOM 2822 C CB  . GLN A 1 394 ? 16.404  -37.172 -139.483 1.00 59.39  ? 394 GLN A CB  1 
ATOM 2823 C CG  . GLN A 1 394 ? 15.767  -36.120 -140.355 1.00 55.22  ? 394 GLN A CG  1 
ATOM 2824 C CD  . GLN A 1 394 ? 14.321  -36.421 -140.641 1.00 62.94  ? 394 GLN A CD  1 
ATOM 2825 O OE1 . GLN A 1 394 ? 13.647  -37.078 -139.852 1.00 75.72  ? 394 GLN A OE1 1 
ATOM 2826 N NE2 . GLN A 1 394 ? 13.830  -35.944 -141.775 1.00 60.94  ? 394 GLN A NE2 1 
ATOM 2827 N N   . ARG A 1 395 ? 18.652  -38.686 -141.260 1.00 54.43  ? 395 ARG A N   1 
ATOM 2828 C CA  . ARG A 1 395 ? 19.499  -38.842 -142.436 1.00 53.90  ? 395 ARG A CA  1 
ATOM 2829 C C   . ARG A 1 395 ? 19.050  -40.033 -143.263 1.00 60.68  ? 395 ARG A C   1 
ATOM 2830 O O   . ARG A 1 395 ? 19.066  -39.985 -144.497 1.00 67.10  ? 395 ARG A O   1 
ATOM 2831 C CB  . ARG A 1 395 ? 20.955  -39.009 -142.016 1.00 58.41  ? 395 ARG A CB  1 
ATOM 2832 C CG  . ARG A 1 395 ? 21.911  -38.054 -142.679 1.00 61.78  ? 395 ARG A CG  1 
ATOM 2833 C CD  . ARG A 1 395 ? 23.329  -38.407 -142.312 1.00 64.83  ? 395 ARG A CD  1 
ATOM 2834 N NE  . ARG A 1 395 ? 23.626  -38.022 -140.939 1.00 66.19  ? 395 ARG A NE  1 
ATOM 2835 C CZ  . ARG A 1 395 ? 24.628  -38.516 -140.225 1.00 69.70  ? 395 ARG A CZ  1 
ATOM 2836 N NH1 . ARG A 1 395 ? 25.433  -39.442 -140.717 1.00 69.54  ? 395 ARG A NH1 1 
ATOM 2837 N NH2 . ARG A 1 395 ? 24.823  -38.072 -138.987 1.00 69.23  ? 395 ARG A NH2 1 
ATOM 2838 N N   . ALA A 1 396 ? 18.666  -41.120 -142.597 1.00 58.71  ? 396 ALA A N   1 
ATOM 2839 C CA  . ALA A 1 396 ? 18.134  -42.269 -143.321 1.00 52.52  ? 396 ALA A CA  1 
ATOM 2840 C C   . ALA A 1 396 ? 16.842  -41.914 -144.044 1.00 53.73  ? 396 ALA A C   1 
ATOM 2841 O O   . ALA A 1 396 ? 16.633  -42.318 -145.191 1.00 63.14  ? 396 ALA A O   1 
ATOM 2842 C CB  . ALA A 1 396 ? 17.903  -43.436 -142.369 1.00 51.49  ? 396 ALA A CB  1 
ATOM 2843 N N   . VAL A 1 397 ? 15.962  -41.165 -143.382 1.00 55.03  ? 397 VAL A N   1 
ATOM 2844 C CA  . VAL A 1 397 ? 14.666  -40.839 -143.973 1.00 50.63  ? 397 VAL A CA  1 
ATOM 2845 C C   . VAL A 1 397 ? 14.835  -39.923 -145.179 1.00 52.65  ? 397 VAL A C   1 
ATOM 2846 O O   . VAL A 1 397 ? 14.209  -40.132 -146.222 1.00 58.57  ? 397 VAL A O   1 
ATOM 2847 C CB  . VAL A 1 397 ? 13.736  -40.213 -142.921 1.00 55.15  ? 397 VAL A CB  1 
ATOM 2848 C CG1 . VAL A 1 397 ? 12.728  -39.302 -143.582 1.00 55.95  ? 397 VAL A CG1 1 
ATOM 2849 C CG2 . VAL A 1 397 ? 13.025  -41.292 -142.145 1.00 61.46  ? 397 VAL A CG2 1 
ATOM 2850 N N   . ASN A 1 398 ? 15.686  -38.901 -145.061 1.00 51.61  ? 398 ASN A N   1 
ATOM 2851 C CA  . ASN A 1 398 ? 15.891  -37.961 -146.156 1.00 45.13  ? 398 ASN A CA  1 
ATOM 2852 C C   . ASN A 1 398 ? 16.406  -38.646 -147.408 1.00 51.87  ? 398 ASN A C   1 
ATOM 2853 O O   . ASN A 1 398 ? 16.274  -38.100 -148.507 1.00 61.86  ? 398 ASN A O   1 
ATOM 2854 C CB  . ASN A 1 398 ? 16.876  -36.870 -145.742 1.00 52.74  ? 398 ASN A CB  1 
ATOM 2855 C CG  . ASN A 1 398 ? 16.321  -35.961 -144.677 1.00 64.45  ? 398 ASN A CG  1 
ATOM 2856 O OD1 . ASN A 1 398 ? 15.110  -35.842 -144.517 1.00 72.52  ? 398 ASN A OD1 1 
ATOM 2857 N ND2 . ASN A 1 398 ? 17.208  -35.307 -143.941 1.00 64.17  ? 398 ASN A ND2 1 
ATOM 2858 N N   . ARG A 1 399 ? 16.996  -39.822 -147.262 1.00 50.57  ? 399 ARG A N   1 
ATOM 2859 C CA  . ARG A 1 399 ? 17.484  -40.621 -148.371 1.00 51.14  ? 399 ARG A CA  1 
ATOM 2860 C C   . ARG A 1 399 ? 16.370  -41.432 -149.022 1.00 55.66  ? 399 ARG A C   1 
ATOM 2861 O O   . ARG A 1 399 ? 16.601  -42.078 -150.048 1.00 56.81  ? 399 ARG A O   1 
ATOM 2862 C CB  . ARG A 1 399 ? 18.618  -41.514 -147.851 1.00 54.70  ? 399 ARG A CB  1 
ATOM 2863 C CG  . ARG A 1 399 ? 19.163  -42.563 -148.780 1.00 64.39  ? 399 ARG A CG  1 
ATOM 2864 C CD  . ARG A 1 399 ? 20.077  -43.502 -148.023 1.00 62.24  ? 399 ARG A CD  1 
ATOM 2865 N NE  . ARG A 1 399 ? 21.038  -42.791 -147.189 1.00 55.68  ? 399 ARG A NE  1 
ATOM 2866 C CZ  . ARG A 1 399 ? 21.987  -41.989 -147.650 1.00 66.66  ? 399 ARG A CZ  1 
ATOM 2867 N NH1 . ARG A 1 399 ? 22.149  -41.780 -148.944 1.00 74.60  ? 399 ARG A NH1 1 
ATOM 2868 N NH2 . ARG A 1 399 ? 22.797  -41.381 -146.790 1.00 74.80  ? 399 ARG A NH2 1 
ATOM 2869 N N   . LYS A 1 400 ? 15.159  -41.368 -148.469 1.00 62.46  ? 400 LYS A N   1 
ATOM 2870 C CA  . LYS A 1 400 ? 14.007  -42.132 -148.939 1.00 59.41  ? 400 LYS A CA  1 
ATOM 2871 C C   . LYS A 1 400 ? 14.214  -43.631 -148.774 1.00 61.34  ? 400 LYS A C   1 
ATOM 2872 O O   . LYS A 1 400 ? 13.755  -44.424 -149.595 1.00 60.45  ? 400 LYS A O   1 
ATOM 2873 C CB  . LYS A 1 400 ? 13.654  -41.793 -150.391 1.00 58.81  ? 400 LYS A CB  1 
ATOM 2874 C CG  . LYS A 1 400 ? 12.532  -40.776 -150.523 1.00 59.40  ? 400 LYS A CG  1 
ATOM 2875 C CD  . LYS A 1 400 ? 12.498  -40.146 -151.906 1.00 66.13  ? 400 LYS A CD  1 
ATOM 2876 C CE  . LYS A 1 400 ? 12.979  -41.110 -152.977 1.00 65.40  ? 400 LYS A CE  1 
ATOM 2877 N NZ  . LYS A 1 400 ? 12.574  -40.672 -154.338 1.00 67.19  ? 400 LYS A NZ  1 
ATOM 2878 N N   . PHE A 1 401 ? 14.914  -44.023 -147.714 1.00 60.03  ? 401 PHE A N   1 
ATOM 2879 C CA  . PHE A 1 401 ? 15.002  -45.418 -147.315 1.00 49.31  ? 401 PHE A CA  1 
ATOM 2880 C C   . PHE A 1 401 ? 13.932  -45.760 -146.289 1.00 53.79  ? 401 PHE A C   1 
ATOM 2881 O O   . PHE A 1 401 ? 13.184  -46.724 -146.462 1.00 64.08  ? 401 PHE A O   1 
ATOM 2882 C CB  . PHE A 1 401 ? 16.394  -45.714 -146.758 1.00 48.45  ? 401 PHE A CB  1 
ATOM 2883 C CG  . PHE A 1 401 ? 16.530  -47.077 -146.153 1.00 55.31  ? 401 PHE A CG  1 
ATOM 2884 C CD1 . PHE A 1 401 ? 16.067  -48.193 -146.817 1.00 60.41  ? 401 PHE A CD1 1 
ATOM 2885 C CD2 . PHE A 1 401 ? 17.132  -47.240 -144.923 1.00 62.20  ? 401 PHE A CD2 1 
ATOM 2886 C CE1 . PHE A 1 401 ? 16.195  -49.444 -146.260 1.00 61.35  ? 401 PHE A CE1 1 
ATOM 2887 C CE2 . PHE A 1 401 ? 17.261  -48.489 -144.365 1.00 59.36  ? 401 PHE A CE2 1 
ATOM 2888 C CZ  . PHE A 1 401 ? 16.793  -49.591 -145.034 1.00 58.97  ? 401 PHE A CZ  1 
ATOM 2889 N N   . LEU A 1 402 ? 13.846  -44.974 -145.225 1.00 56.44  ? 402 LEU A N   1 
ATOM 2890 C CA  . LEU A 1 402 ? 12.806  -45.103 -144.219 1.00 54.92  ? 402 LEU A CA  1 
ATOM 2891 C C   . LEU A 1 402 ? 11.702  -44.086 -144.483 1.00 60.66  ? 402 LEU A C   1 
ATOM 2892 O O   . LEU A 1 402 ? 11.824  -43.202 -145.330 1.00 66.36  ? 402 LEU A O   1 
ATOM 2893 C CB  . LEU A 1 402 ? 13.385  -44.894 -142.820 1.00 47.76  ? 402 LEU A CB  1 
ATOM 2894 C CG  . LEU A 1 402 ? 14.319  -45.957 -142.261 1.00 44.88  ? 402 LEU A CG  1 
ATOM 2895 C CD1 . LEU A 1 402 ? 14.857  -45.502 -140.929 1.00 51.82  ? 402 LEU A CD1 1 
ATOM 2896 C CD2 . LEU A 1 402 ? 13.580  -47.258 -142.114 1.00 57.60  ? 402 LEU A CD2 1 
ATOM 2897 N N   . SER A 1 403 ? 10.607  -44.229 -143.743 1.00 67.43  ? 403 SER A N   1 
ATOM 2898 C CA  . SER A 1 403 ? 9.534   -43.245 -143.750 1.00 62.33  ? 403 SER A CA  1 
ATOM 2899 C C   . SER A 1 403 ? 9.386   -42.542 -142.412 1.00 64.50  ? 403 SER A C   1 
ATOM 2900 O O   . SER A 1 403 ? 9.363   -41.311 -142.359 1.00 74.29  ? 403 SER A O   1 
ATOM 2901 C CB  . SER A 1 403 ? 8.209   -43.905 -144.141 1.00 62.76  ? 403 SER A CB  1 
ATOM 2902 O OG  . SER A 1 403 ? 8.217   -44.266 -145.508 1.00 70.32  ? 403 SER A OG  1 
ATOM 2903 N N   . THR A 1 404 ? 9.274   -43.294 -141.324 1.00 63.84  ? 404 THR A N   1 
ATOM 2904 C CA  . THR A 1 404 ? 9.196   -42.729 -139.987 1.00 66.21  ? 404 THR A CA  1 
ATOM 2905 C C   . THR A 1 404 ? 10.185  -43.455 -139.089 1.00 61.01  ? 404 THR A C   1 
ATOM 2906 O O   . THR A 1 404 ? 10.880  -44.379 -139.512 1.00 63.91  ? 404 THR A O   1 
ATOM 2907 C CB  . THR A 1 404 ? 7.781   -42.833 -139.404 1.00 77.61  ? 404 THR A CB  1 
ATOM 2908 O OG1 . THR A 1 404 ? 7.641   -44.084 -138.723 1.00 85.60  ? 404 THR A OG1 1 
ATOM 2909 C CG2 . THR A 1 404 ? 6.731   -42.750 -140.499 1.00 72.14  ? 404 THR A CG2 1 
ATOM 2910 N N   . TYR A 1 405 ? 10.242  -43.029 -137.832 1.00 52.35  ? 405 TYR A N   1 
ATOM 2911 C CA  . TYR A 1 405 ? 11.085  -43.675 -136.840 1.00 59.86  ? 405 TYR A CA  1 
ATOM 2912 C C   . TYR A 1 405 ? 10.674  -43.188 -135.462 1.00 67.20  ? 405 TYR A C   1 
ATOM 2913 O O   . TYR A 1 405 ? 10.190  -42.065 -135.308 1.00 78.34  ? 405 TYR A O   1 
ATOM 2914 C CB  . TYR A 1 405 ? 12.567  -43.383 -137.076 1.00 59.98  ? 405 TYR A CB  1 
ATOM 2915 C CG  . TYR A 1 405 ? 12.872  -41.914 -137.181 1.00 65.41  ? 405 TYR A CG  1 
ATOM 2916 C CD1 . TYR A 1 405 ? 12.806  -41.262 -138.400 1.00 66.16  ? 405 TYR A CD1 1 
ATOM 2917 C CD2 . TYR A 1 405 ? 13.218  -41.176 -136.065 1.00 59.78  ? 405 TYR A CD2 1 
ATOM 2918 C CE1 . TYR A 1 405 ? 13.079  -39.921 -138.502 1.00 56.88  ? 405 TYR A CE1 1 
ATOM 2919 C CE2 . TYR A 1 405 ? 13.490  -39.834 -136.158 1.00 54.87  ? 405 TYR A CE2 1 
ATOM 2920 C CZ  . TYR A 1 405 ? 13.419  -39.213 -137.380 1.00 54.00  ? 405 TYR A CZ  1 
ATOM 2921 O OH  . TYR A 1 405 ? 13.693  -37.872 -137.484 1.00 66.21  ? 405 TYR A OH  1 
ATOM 2922 N N   . THR A 1 406 ? 10.862  -44.045 -134.467 1.00 65.80  ? 406 THR A N   1 
ATOM 2923 C CA  . THR A 1 406 ? 10.664  -43.682 -133.073 1.00 67.40  ? 406 THR A CA  1 
ATOM 2924 C C   . THR A 1 406 ? 11.884  -44.120 -132.285 1.00 68.71  ? 406 THR A C   1 
ATOM 2925 O O   . THR A 1 406 ? 12.471  -45.165 -132.572 1.00 70.89  ? 406 THR A O   1 
ATOM 2926 C CB  . THR A 1 406 ? 9.412   -44.331 -132.483 1.00 68.16  ? 406 THR A CB  1 
ATOM 2927 O OG1 . THR A 1 406 ? 9.720   -45.667 -132.071 1.00 76.71  ? 406 THR A OG1 1 
ATOM 2928 C CG2 . THR A 1 406 ? 8.297   -44.376 -133.505 1.00 62.78  ? 406 THR A CG2 1 
ATOM 2929 N N   . VAL A 1 407 ? 12.272  -43.322 -131.296 1.00 59.47  ? 407 VAL A N   1 
ATOM 2930 C CA  . VAL A 1 407 ? 13.423  -43.623 -130.456 1.00 58.42  ? 407 VAL A CA  1 
ATOM 2931 C C   . VAL A 1 407 ? 12.985  -43.571 -129.002 1.00 65.46  ? 407 VAL A C   1 
ATOM 2932 O O   . VAL A 1 407 ? 12.339  -42.606 -128.579 1.00 72.97  ? 407 VAL A O   1 
ATOM 2933 C CB  . VAL A 1 407 ? 14.587  -42.648 -130.703 1.00 57.25  ? 407 VAL A CB  1 
ATOM 2934 C CG1 . VAL A 1 407 ? 15.739  -42.972 -129.785 1.00 56.86  ? 407 VAL A CG1 1 
ATOM 2935 C CG2 . VAL A 1 407 ? 15.030  -42.721 -132.141 1.00 63.23  ? 407 VAL A CG2 1 
ATOM 2936 N N   . THR A 1 408 ? 13.334  -44.603 -128.243 1.00 62.23  ? 408 THR A N   1 
ATOM 2937 C CA  . THR A 1 408 ? 13.003  -44.697 -126.828 1.00 56.37  ? 408 THR A CA  1 
ATOM 2938 C C   . THR A 1 408 ? 14.293  -44.875 -126.045 1.00 61.87  ? 408 THR A C   1 
ATOM 2939 O O   . THR A 1 408 ? 15.053  -45.812 -126.306 1.00 69.37  ? 408 THR A O   1 
ATOM 2940 C CB  . THR A 1 408 ? 12.052  -45.863 -126.569 1.00 59.64  ? 408 THR A CB  1 
ATOM 2941 O OG1 . THR A 1 408 ? 10.872  -45.699 -127.362 1.00 68.22  ? 408 THR A OG1 1 
ATOM 2942 C CG2 . THR A 1 408 ? 11.670  -45.925 -125.106 1.00 62.98  ? 408 THR A CG2 1 
ATOM 2943 N N   . VAL A 1 409 ? 14.535  -43.988 -125.086 1.00 63.41  ? 409 VAL A N   1 
ATOM 2944 C CA  . VAL A 1 409 ? 15.764  -44.034 -124.298 1.00 60.56  ? 409 VAL A CA  1 
ATOM 2945 C C   . VAL A 1 409 ? 15.409  -44.078 -122.818 1.00 62.56  ? 409 VAL A C   1 
ATOM 2946 O O   . VAL A 1 409 ? 14.381  -43.520 -122.409 1.00 71.20  ? 409 VAL A O   1 
ATOM 2947 C CB  . VAL A 1 409 ? 16.671  -42.838 -124.615 1.00 52.89  ? 409 VAL A CB  1 
ATOM 2948 C CG1 . VAL A 1 409 ? 17.042  -42.837 -126.076 1.00 57.67  ? 409 VAL A CG1 1 
ATOM 2949 C CG2 . VAL A 1 409 ? 15.979  -41.548 -124.253 1.00 63.43  ? 409 VAL A CG2 1 
ATOM 2950 N N   . PRO A 1 410 ? 16.214  -44.724 -121.984 1.00 65.09  ? 410 PRO A N   1 
ATOM 2951 C CA  . PRO A 1 410 ? 15.882  -44.824 -120.564 1.00 72.12  ? 410 PRO A CA  1 
ATOM 2952 C C   . PRO A 1 410 ? 16.189  -43.537 -119.815 1.00 75.79  ? 410 PRO A C   1 
ATOM 2953 O O   . PRO A 1 410 ? 17.059  -42.752 -120.191 1.00 80.59  ? 410 PRO A O   1 
ATOM 2954 C CB  . PRO A 1 410 ? 16.777  -45.964 -120.072 1.00 73.84  ? 410 PRO A CB  1 
ATOM 2955 C CG  . PRO A 1 410 ? 17.929  -45.958 -120.996 1.00 72.55  ? 410 PRO A CG  1 
ATOM 2956 C CD  . PRO A 1 410 ? 17.477  -45.403 -122.311 1.00 67.00  ? 410 PRO A CD  1 
ATOM 2957 N N   . LYS A 1 411 ? 15.449  -43.335 -118.731 1.00 86.44  ? 411 LYS A N   1 
ATOM 2958 C CA  . LYS A 1 411 ? 15.694  -42.201 -117.859 1.00 82.24  ? 411 LYS A CA  1 
ATOM 2959 C C   . LYS A 1 411 ? 16.924  -42.463 -116.997 1.00 83.07  ? 411 LYS A C   1 
ATOM 2960 O O   . LYS A 1 411 ? 17.371  -43.599 -116.833 1.00 87.55  ? 411 LYS A O   1 
ATOM 2961 C CB  . LYS A 1 411 ? 14.482  -41.932 -116.972 1.00 81.72  ? 411 LYS A CB  1 
ATOM 2962 C CG  . LYS A 1 411 ? 13.186  -41.740 -117.736 1.00 84.08  ? 411 LYS A CG  1 
ATOM 2963 C CD  . LYS A 1 411 ? 12.089  -41.216 -116.826 1.00 86.74  ? 411 LYS A CD  1 
ATOM 2964 C CE  . LYS A 1 411 ? 10.794  -41.002 -117.588 1.00 87.07  ? 411 LYS A CE  1 
ATOM 2965 N NZ  . LYS A 1 411 ? 9.686   -40.599 -116.680 1.00 87.01  ? 411 LYS A NZ  1 
ATOM 2966 N N   . ALA A 1 412 ? 17.475  -41.386 -116.439 1.00 77.27  ? 412 ALA A N   1 
ATOM 2967 C CA  . ALA A 1 412 ? 18.676  -41.517 -115.626 1.00 79.55  ? 412 ALA A CA  1 
ATOM 2968 C C   . ALA A 1 412 ? 18.427  -42.277 -114.332 1.00 82.23  ? 412 ALA A C   1 
ATOM 2969 O O   . ALA A 1 412 ? 19.364  -42.863 -113.786 1.00 84.71  ? 412 ALA A O   1 
ATOM 2970 C CB  . ALA A 1 412 ? 19.254  -40.141 -115.310 1.00 80.15  ? 412 ALA A CB  1 
ATOM 2971 N N   . SER A 1 413 ? 17.197  -42.277 -113.827 1.00 87.99  ? 413 SER A N   1 
ATOM 2972 C CA  . SER A 1 413 ? 16.890  -42.949 -112.575 1.00 86.42  ? 413 SER A CA  1 
ATOM 2973 C C   . SER A 1 413 ? 16.543  -44.419 -112.751 1.00 86.84  ? 413 SER A C   1 
ATOM 2974 O O   . SER A 1 413 ? 16.440  -45.137 -111.753 1.00 87.33  ? 413 SER A O   1 
ATOM 2975 C CB  . SER A 1 413 ? 15.731  -42.245 -111.868 1.00 89.27  ? 413 SER A CB  1 
ATOM 2976 O OG  . SER A 1 413 ? 14.569  -42.248 -112.676 1.00 90.30  ? 413 SER A OG  1 
ATOM 2977 N N   . GLN A 1 414 ? 16.359  -44.885 -113.983 1.00 88.79  ? 414 GLN A N   1 
ATOM 2978 C CA  . GLN A 1 414 ? 16.024  -46.275 -114.245 1.00 89.50  ? 414 GLN A CA  1 
ATOM 2979 C C   . GLN A 1 414 ? 17.225  -47.092 -114.692 1.00 93.39  ? 414 GLN A C   1 
ATOM 2980 O O   . GLN A 1 414 ? 17.065  -48.253 -115.076 1.00 100.36 ? 414 GLN A O   1 
ATOM 2981 C CB  . GLN A 1 414 ? 14.915  -46.362 -115.291 1.00 91.01  ? 414 GLN A CB  1 
ATOM 2982 C CG  . GLN A 1 414 ? 14.024  -45.139 -115.331 1.00 92.65  ? 414 GLN A CG  1 
ATOM 2983 C CD  . GLN A 1 414 ? 13.124  -45.109 -116.549 1.00 95.36  ? 414 GLN A CD  1 
ATOM 2984 O OE1 . GLN A 1 414 ? 13.590  -44.940 -117.675 1.00 98.94  ? 414 GLN A OE1 1 
ATOM 2985 N NE2 . GLN A 1 414 ? 11.826  -45.268 -116.328 1.00 92.09  ? 414 GLN A NE2 1 
ATOM 2986 N N   . VAL A 1 415 ? 18.420  -46.516 -114.652 1.00 78.00  ? 415 VAL A N   1 
ATOM 2987 C CA  . VAL A 1 415 ? 19.643  -47.213 -115.021 1.00 78.98  ? 415 VAL A CA  1 
ATOM 2988 C C   . VAL A 1 415 ? 20.312  -47.705 -113.748 1.00 82.00  ? 415 VAL A C   1 
ATOM 2989 O O   . VAL A 1 415 ? 20.549  -46.922 -112.820 1.00 84.80  ? 415 VAL A O   1 
ATOM 2990 C CB  . VAL A 1 415 ? 20.582  -46.302 -115.823 1.00 76.55  ? 415 VAL A CB  1 
ATOM 2991 C CG1 . VAL A 1 415 ? 21.866  -47.029 -116.144 1.00 81.49  ? 415 VAL A CG1 1 
ATOM 2992 C CG2 . VAL A 1 415 ? 19.902  -45.851 -117.091 1.00 78.98  ? 415 VAL A CG2 1 
ATOM 2993 N N   . ALA A 1 416 ? 20.614  -48.996 -113.700 1.00 73.42  ? 416 ALA A N   1 
ATOM 2994 C CA  . ALA A 1 416 ? 21.171  -49.582 -112.494 1.00 75.12  ? 416 ALA A CA  1 
ATOM 2995 C C   . ALA A 1 416 ? 22.601  -49.104 -112.272 1.00 80.22  ? 416 ALA A C   1 
ATOM 2996 O O   . ALA A 1 416 ? 23.302  -48.696 -113.199 1.00 81.23  ? 416 ALA A O   1 
ATOM 2997 C CB  . ALA A 1 416 ? 21.133  -51.105 -112.574 1.00 78.51  ? 416 ALA A CB  1 
ATOM 2998 N N   . LEU A 1 417 ? 23.031  -49.160 -111.009 1.00 78.02  ? 417 LEU A N   1 
ATOM 2999 C CA  . LEU A 1 417 ? 24.389  -48.756 -110.667 1.00 71.13  ? 417 LEU A CA  1 
ATOM 3000 C C   . LEU A 1 417 ? 25.426  -49.622 -111.365 1.00 77.37  ? 417 LEU A C   1 
ATOM 3001 O O   . LEU A 1 417 ? 26.543  -49.162 -111.628 1.00 80.40  ? 417 LEU A O   1 
ATOM 3002 C CB  . LEU A 1 417 ? 24.589  -48.818 -109.155 1.00 71.15  ? 417 LEU A CB  1 
ATOM 3003 C CG  . LEU A 1 417 ? 25.973  -48.410 -108.659 1.00 73.09  ? 417 LEU A CG  1 
ATOM 3004 C CD1 . LEU A 1 417 ? 26.247  -46.973 -109.036 1.00 76.05  ? 417 LEU A CD1 1 
ATOM 3005 C CD2 . LEU A 1 417 ? 26.090  -48.610 -107.162 1.00 75.04  ? 417 LEU A CD2 1 
ATOM 3006 N N   . ALA A 1 418 ? 25.078  -50.871 -111.670 1.00 70.59  ? 418 ALA A N   1 
ATOM 3007 C CA  . ALA A 1 418 ? 26.016  -51.752 -112.352 1.00 68.83  ? 418 ALA A CA  1 
ATOM 3008 C C   . ALA A 1 418 ? 26.426  -51.179 -113.699 1.00 72.01  ? 418 ALA A C   1 
ATOM 3009 O O   . ALA A 1 418 ? 27.580  -51.314 -114.116 1.00 77.48  ? 418 ALA A O   1 
ATOM 3010 C CB  . ALA A 1 418 ? 25.399  -53.139 -112.525 1.00 68.65  ? 418 ALA A CB  1 
ATOM 3011 N N   . ASP A 1 419 ? 25.492  -50.533 -114.394 1.00 77.60  ? 419 ASP A N   1 
ATOM 3012 C CA  . ASP A 1 419 ? 25.814  -49.922 -115.676 1.00 79.99  ? 419 ASP A CA  1 
ATOM 3013 C C   . ASP A 1 419 ? 26.605  -48.633 -115.503 1.00 80.10  ? 419 ASP A C   1 
ATOM 3014 O O   . ASP A 1 419 ? 27.538  -48.369 -116.267 1.00 84.68  ? 419 ASP A O   1 
ATOM 3015 C CB  . ASP A 1 419 ? 24.535  -49.655 -116.462 1.00 81.66  ? 419 ASP A CB  1 
ATOM 3016 C CG  . ASP A 1 419 ? 24.235  -50.748 -117.455 1.00 89.19  ? 419 ASP A CG  1 
ATOM 3017 O OD1 . ASP A 1 419 ? 25.180  -51.469 -117.832 1.00 92.03  ? 419 ASP A OD1 1 
ATOM 3018 O OD2 . ASP A 1 419 ? 23.060  -50.890 -117.856 1.00 85.99  ? 419 ASP A OD2 1 
ATOM 3019 N N   . LYS A 1 420 ? 26.145  -47.758 -114.616 1.00 64.87  ? 420 LYS A N   1 
ATOM 3020 C CA  . LYS A 1 420 ? 26.807  -46.437 -114.501 1.00 60.47  ? 420 LYS A CA  1 
ATOM 3021 C C   . LYS A 1 420 ? 28.275  -46.650 -114.140 1.00 64.72  ? 420 LYS A C   1 
ATOM 3022 O O   . LYS A 1 420 ? 29.122  -45.890 -114.611 1.00 66.55  ? 420 LYS A O   1 
ATOM 3023 C CB  . LYS A 1 420 ? 26.126  -45.562 -113.449 1.00 61.69  ? 420 LYS A CB  1 
ATOM 3024 C CG  . LYS A 1 420 ? 24.613  -45.522 -113.519 1.00 64.31  ? 420 LYS A CG  1 
ATOM 3025 C CD  . LYS A 1 420 ? 24.052  -44.273 -112.855 1.00 65.56  ? 420 LYS A CD  1 
ATOM 3026 C CE  . LYS A 1 420 ? 22.658  -43.980 -113.295 1.00 67.44  ? 420 LYS A CE  1 
ATOM 3027 N NZ  . LYS A 1 420 ? 21.676  -44.430 -112.309 1.00 72.01  ? 420 LYS A NZ  1 
ATOM 3028 N N   . LYS A 1 421 ? 28.545  -47.652 -113.318 1.00 65.42  ? 421 LYS A N   1 
ATOM 3029 C CA  . LYS A 1 421 ? 29.939  -47.923 -112.914 1.00 64.28  ? 421 LYS A CA  1 
ATOM 3030 C C   . LYS A 1 421 ? 30.737  -48.185 -114.187 1.00 66.97  ? 421 LYS A C   1 
ATOM 3031 O O   . LYS A 1 421 ? 31.775  -47.544 -114.373 1.00 71.82  ? 421 LYS A O   1 
ATOM 3032 C CB  . LYS A 1 421 ? 30.001  -49.124 -111.973 1.00 60.73  ? 421 LYS A CB  1 
ATOM 3033 C CG  . LYS A 1 421 ? 30.926  -48.950 -110.786 1.00 65.89  ? 421 LYS A CG  1 
ATOM 3034 C CD  . LYS A 1 421 ? 30.210  -48.354 -109.582 1.00 70.51  ? 421 LYS A CD  1 
ATOM 3035 C CE  . LYS A 1 421 ? 29.600  -49.413 -108.725 1.00 61.92  ? 421 LYS A CE  1 
ATOM 3036 N NZ  . LYS A 1 421 ? 30.496  -50.561 -108.574 1.00 53.16  ? 421 LYS A NZ  1 
ATOM 3037 N N   . ALA A 1 422 ? 30.261  -49.099 -115.025 1.00 63.13  ? 422 ALA A N   1 
ATOM 3038 C CA  . ALA A 1 422 ? 30.994  -49.441 -116.260 1.00 60.36  ? 422 ALA A CA  1 
ATOM 3039 C C   . ALA A 1 422 ? 30.802  -48.328 -117.276 1.00 64.81  ? 422 ALA A C   1 
ATOM 3040 O O   . ALA A 1 422 ? 31.049  -48.566 -118.464 1.00 65.67  ? 422 ALA A O   1 
ATOM 3041 C CB  . ALA A 1 422 ? 30.497  -50.739 -116.807 1.00 53.74  ? 422 ALA A CB  1 
ATOM 3042 N N   . ARG A 1 423 ? 30.351  -47.163 -116.823 1.00 66.08  ? 423 ARG A N   1 
ATOM 3043 C CA  . ARG A 1 423 ? 30.234  -46.031 -117.735 1.00 62.88  ? 423 ARG A CA  1 
ATOM 3044 C C   . ARG A 1 423 ? 29.728  -46.460 -119.104 1.00 64.01  ? 423 ARG A C   1 
ATOM 3045 O O   . ARG A 1 423 ? 30.356  -46.158 -120.121 1.00 70.29  ? 423 ARG A O   1 
ATOM 3046 C CB  . ARG A 1 423 ? 31.573  -45.302 -117.881 1.00 63.08  ? 423 ARG A CB  1 
ATOM 3047 C CG  . ARG A 1 423 ? 32.285  -44.991 -116.571 1.00 64.34  ? 423 ARG A CG  1 
ATOM 3048 C CD  . ARG A 1 423 ? 33.760  -44.681 -116.803 1.00 67.76  ? 423 ARG A CD  1 
ATOM 3049 N NE  . ARG A 1 423 ? 34.602  -45.047 -115.669 1.00 72.49  ? 423 ARG A NE  1 
ATOM 3050 C CZ  . ARG A 1 423 ? 35.481  -46.041 -115.675 1.00 61.13  ? 423 ARG A CZ  1 
ATOM 3051 N NH1 . ARG A 1 423 ? 35.649  -46.811 -116.737 1.00 48.18  ? 423 ARG A NH1 1 
ATOM 3052 N NH2 . ARG A 1 423 ? 36.209  -46.267 -114.586 1.00 47.06  ? 423 ARG A NH2 1 
ATOM 3053 N N   . ILE A 1 424 ? 28.603  -47.168 -119.143 1.00 57.11  ? 424 ILE A N   1 
ATOM 3054 C CA  . ILE A 1 424 ? 28.011  -47.636 -120.389 1.00 54.52  ? 424 ILE A CA  1 
ATOM 3055 C C   . ILE A 1 424 ? 26.524  -47.322 -120.356 1.00 57.03  ? 424 ILE A C   1 
ATOM 3056 O O   . ILE A 1 424 ? 25.929  -47.232 -119.277 1.00 66.09  ? 424 ILE A O   1 
ATOM 3057 C CB  . ILE A 1 424 ? 28.247  -49.143 -120.604 1.00 55.15  ? 424 ILE A CB  1 
ATOM 3058 C CG1 . ILE A 1 424 ? 27.901  -49.549 -122.032 1.00 56.90  ? 424 ILE A CG1 1 
ATOM 3059 C CG2 . ILE A 1 424 ? 27.425  -49.953 -119.635 1.00 60.48  ? 424 ILE A CG2 1 
ATOM 3060 C CD1 . ILE A 1 424 ? 28.619  -50.787 -122.495 1.00 57.25  ? 424 ILE A CD1 1 
ATOM 3061 N N   . LEU A 1 425 ? 25.934  -47.128 -121.529 1.00 50.97  ? 425 LEU A N   1 
ATOM 3062 C CA  . LEU A 1 425 ? 24.499  -46.912 -121.666 1.00 42.37  ? 425 LEU A CA  1 
ATOM 3063 C C   . LEU A 1 425 ? 23.918  -48.040 -122.504 1.00 57.87  ? 425 LEU A C   1 
ATOM 3064 O O   . LEU A 1 425 ? 24.406  -48.315 -123.605 1.00 66.36  ? 425 LEU A O   1 
ATOM 3065 C CB  . LEU A 1 425 ? 24.213  -45.558 -122.308 1.00 39.98  ? 425 LEU A CB  1 
ATOM 3066 C CG  . LEU A 1 425 ? 22.742  -45.159 -122.361 1.00 46.72  ? 425 LEU A CG  1 
ATOM 3067 C CD1 . LEU A 1 425 ? 22.197  -45.010 -120.966 1.00 57.31  ? 425 LEU A CD1 1 
ATOM 3068 C CD2 . LEU A 1 425 ? 22.580  -43.867 -123.124 1.00 41.30  ? 425 LEU A CD2 1 
ATOM 3069 N N   . LYS A 1 426 ? 22.885  -48.690 -121.990 1.00 64.42  ? 426 LYS A N   1 
ATOM 3070 C CA  . LYS A 1 426 ? 22.322  -49.863 -122.633 1.00 67.28  ? 426 LYS A CA  1 
ATOM 3071 C C   . LYS A 1 426 ? 20.864  -49.625 -123.007 1.00 68.98  ? 426 LYS A C   1 
ATOM 3072 O O   . LYS A 1 426 ? 20.360  -48.501 -122.944 1.00 63.51  ? 426 LYS A O   1 
ATOM 3073 C CB  . LYS A 1 426 ? 22.469  -51.083 -121.725 1.00 65.09  ? 426 LYS A CB  1 
ATOM 3074 C CG  . LYS A 1 426 ? 23.885  -51.374 -121.298 1.00 64.28  ? 426 LYS A CG  1 
ATOM 3075 C CD  . LYS A 1 426 ? 23.937  -52.629 -120.455 1.00 64.22  ? 426 LYS A CD  1 
ATOM 3076 C CE  . LYS A 1 426 ? 24.069  -53.866 -121.317 1.00 71.75  ? 426 LYS A CE  1 
ATOM 3077 N NZ  . LYS A 1 426 ? 25.324  -53.855 -122.113 1.00 75.01  ? 426 LYS A NZ  1 
ATOM 3078 N N   . ASP A 1 427 ? 20.212  -50.700 -123.453 1.00 83.46  ? 427 ASP A N   1 
ATOM 3079 C CA  . ASP A 1 427 ? 18.782  -50.808 -123.734 1.00 84.78  ? 427 ASP A CA  1 
ATOM 3080 C C   . ASP A 1 427 ? 18.148  -49.559 -124.343 1.00 83.55  ? 427 ASP A C   1 
ATOM 3081 O O   . ASP A 1 427 ? 17.049  -49.149 -123.956 1.00 81.43  ? 427 ASP A O   1 
ATOM 3082 C CB  . ASP A 1 427 ? 18.046  -51.286 -122.466 1.00 84.02  ? 427 ASP A CB  1 
ATOM 3083 C CG  . ASP A 1 427 ? 17.771  -50.186 -121.448 1.00 90.85  ? 427 ASP A CG  1 
ATOM 3084 O OD1 . ASP A 1 427 ? 18.307  -49.070 -121.558 1.00 87.35  ? 427 ASP A OD1 1 
ATOM 3085 O OD2 . ASP A 1 427 ? 16.991  -50.455 -120.512 1.00 96.76  ? 427 ASP A OD2 1 
ATOM 3086 N N   . ILE A 1 428 ? 18.808  -48.985 -125.341 1.00 67.52  ? 428 ILE A N   1 
ATOM 3087 C CA  . ILE A 1 428 ? 18.194  -47.986 -126.205 1.00 59.80  ? 428 ILE A CA  1 
ATOM 3088 C C   . ILE A 1 428 ? 17.569  -48.707 -127.387 1.00 65.81  ? 428 ILE A C   1 
ATOM 3089 O O   . ILE A 1 428 ? 18.224  -49.529 -128.039 1.00 71.56  ? 428 ILE A O   1 
ATOM 3090 C CB  . ILE A 1 428 ? 19.224  -46.954 -126.686 1.00 55.81  ? 428 ILE A CB  1 
ATOM 3091 C CG1 . ILE A 1 428 ? 19.682  -46.068 -125.537 1.00 62.01  ? 428 ILE A CG1 1 
ATOM 3092 C CG2 . ILE A 1 428 ? 18.637  -46.108 -127.789 1.00 54.47  ? 428 ILE A CG2 1 
ATOM 3093 C CD1 . ILE A 1 428 ? 20.620  -44.981 -125.977 1.00 62.38  ? 428 ILE A CD1 1 
ATOM 3094 N N   . THR A 1 429 ? 16.305  -48.417 -127.663 1.00 61.70  ? 429 THR A N   1 
ATOM 3095 C CA  . THR A 1 429 ? 15.605  -49.037 -128.773 1.00 64.53  ? 429 THR A CA  1 
ATOM 3096 C C   . THR A 1 429 ? 15.122  -47.978 -129.748 1.00 65.62  ? 429 THR A C   1 
ATOM 3097 O O   . THR A 1 429 ? 14.815  -46.848 -129.363 1.00 69.24  ? 429 THR A O   1 
ATOM 3098 C CB  . THR A 1 429 ? 14.413  -49.868 -128.303 1.00 68.72  ? 429 THR A CB  1 
ATOM 3099 O OG1 . THR A 1 429 ? 13.673  -50.315 -129.445 1.00 71.53  ? 429 THR A OG1 1 
ATOM 3100 C CG2 . THR A 1 429 ? 13.505  -49.050 -127.422 1.00 68.95  ? 429 THR A CG2 1 
ATOM 3101 N N   . PHE A 1 430 ? 15.075  -48.354 -131.021 1.00 62.44  ? 430 PHE A N   1 
ATOM 3102 C CA  . PHE A 1 430 ? 14.495  -47.514 -132.052 1.00 64.12  ? 430 PHE A CA  1 
ATOM 3103 C C   . PHE A 1 430 ? 13.818  -48.399 -133.083 1.00 63.93  ? 430 PHE A C   1 
ATOM 3104 O O   . PHE A 1 430 ? 14.174  -49.567 -133.248 1.00 68.66  ? 430 PHE A O   1 
ATOM 3105 C CB  . PHE A 1 430 ? 15.542  -46.617 -132.727 1.00 62.32  ? 430 PHE A CB  1 
ATOM 3106 C CG  . PHE A 1 430 ? 16.506  -47.357 -133.604 1.00 55.55  ? 430 PHE A CG  1 
ATOM 3107 C CD1 . PHE A 1 430 ? 17.627  -47.954 -133.070 1.00 60.05  ? 430 PHE A CD1 1 
ATOM 3108 C CD2 . PHE A 1 430 ? 16.297  -47.440 -134.966 1.00 58.96  ? 430 PHE A CD2 1 
ATOM 3109 C CE1 . PHE A 1 430 ? 18.516  -48.626 -133.876 1.00 63.91  ? 430 PHE A CE1 1 
ATOM 3110 C CE2 . PHE A 1 430 ? 17.181  -48.114 -135.774 1.00 65.34  ? 430 PHE A CE2 1 
ATOM 3111 C CZ  . PHE A 1 430 ? 18.291  -48.706 -135.229 1.00 64.32  ? 430 PHE A CZ  1 
ATOM 3112 N N   . HIS A 1 431 ? 12.838  -47.831 -133.772 1.00 61.98  ? 431 HIS A N   1 
ATOM 3113 C CA  . HIS A 1 431 ? 12.082  -48.544 -134.786 1.00 65.35  ? 431 HIS A CA  1 
ATOM 3114 C C   . HIS A 1 431 ? 12.041  -47.710 -136.056 1.00 72.32  ? 431 HIS A C   1 
ATOM 3115 O O   . HIS A 1 431 ? 12.175  -46.488 -136.016 1.00 77.72  ? 431 HIS A O   1 
ATOM 3116 C CB  . HIS A 1 431 ? 10.661  -48.846 -134.315 1.00 65.27  ? 431 HIS A CB  1 
ATOM 3117 C CG  . HIS A 1 431 ? 9.861   -49.646 -135.293 1.00 71.70  ? 431 HIS A CG  1 
ATOM 3118 N ND1 . HIS A 1 431 ? 10.092  -50.983 -135.525 1.00 73.60  ? 431 HIS A ND1 1 
ATOM 3119 C CD2 . HIS A 1 431 ? 8.840   -49.293 -136.107 1.00 68.28  ? 431 HIS A CD2 1 
ATOM 3120 C CE1 . HIS A 1 431 ? 9.244   -51.423 -136.435 1.00 74.40  ? 431 HIS A CE1 1 
ATOM 3121 N NE2 . HIS A 1 431 ? 8.473   -50.416 -136.805 1.00 71.80  ? 431 HIS A NE2 1 
ATOM 3122 N N   . GLY A 1 432 ? 11.867  -48.381 -137.184 1.00 70.09  ? 432 GLY A N   1 
ATOM 3123 C CA  . GLY A 1 432 ? 11.778  -47.699 -138.460 1.00 64.42  ? 432 GLY A CA  1 
ATOM 3124 C C   . GLY A 1 432 ? 10.793  -48.395 -139.373 1.00 60.90  ? 432 GLY A C   1 
ATOM 3125 O O   . GLY A 1 432 ? 10.558  -49.598 -139.266 1.00 70.17  ? 432 GLY A O   1 
ATOM 3126 N N   . ILE A 1 433 ? 10.209  -47.614 -140.275 1.00 51.06  ? 433 ILE A N   1 
ATOM 3127 C CA  . ILE A 1 433 ? 9.274   -48.119 -141.271 1.00 56.76  ? 433 ILE A CA  1 
ATOM 3128 C C   . ILE A 1 433 ? 9.847   -47.820 -142.646 1.00 59.53  ? 433 ILE A C   1 
ATOM 3129 O O   . ILE A 1 433 ? 10.122  -46.661 -142.974 1.00 66.45  ? 433 ILE A O   1 
ATOM 3130 C CB  . ILE A 1 433 ? 7.878   -47.505 -141.104 1.00 55.88  ? 433 ILE A CB  1 
ATOM 3131 C CG1 . ILE A 1 433 ? 7.200   -48.073 -139.861 1.00 64.95  ? 433 ILE A CG1 1 
ATOM 3132 C CG2 . ILE A 1 433 ? 7.037   -47.765 -142.330 1.00 60.82  ? 433 ILE A CG2 1 
ATOM 3133 C CD1 . ILE A 1 433 ? 7.265   -47.177 -138.664 1.00 67.05  ? 433 ILE A CD1 1 
ATOM 3134 N N   . LEU A 1 434 ? 10.021  -48.861 -143.449 1.00 53.32  ? 434 LEU A N   1 
ATOM 3135 C CA  . LEU A 1 434 ? 10.629  -48.718 -144.758 1.00 43.66  ? 434 LEU A CA  1 
ATOM 3136 C C   . LEU A 1 434 ? 9.632   -48.145 -145.753 1.00 51.47  ? 434 LEU A C   1 
ATOM 3137 O O   . LEU A 1 434 ? 8.424   -48.108 -145.513 1.00 64.34  ? 434 LEU A O   1 
ATOM 3138 C CB  . LEU A 1 434 ? 11.147  -50.059 -145.273 1.00 41.90  ? 434 LEU A CB  1 
ATOM 3139 C CG  . LEU A 1 434 ? 11.939  -50.965 -144.335 1.00 54.53  ? 434 LEU A CG  1 
ATOM 3140 C CD1 . LEU A 1 434 ? 11.030  -51.812 -143.457 1.00 53.09  ? 434 LEU A CD1 1 
ATOM 3141 C CD2 . LEU A 1 434 ? 12.865  -51.844 -145.131 1.00 59.50  ? 434 LEU A CD2 1 
ATOM 3142 N N   . ALA A 1 435 ? 10.158  -47.691 -146.884 1.00 59.29  ? 435 ALA A N   1 
ATOM 3143 C CA  . ALA A 1 435 ? 9.355   -47.243 -148.012 1.00 65.06  ? 435 ALA A CA  1 
ATOM 3144 C C   . ALA A 1 435 ? 9.703   -48.114 -149.207 1.00 66.18  ? 435 ALA A C   1 
ATOM 3145 O O   . ALA A 1 435 ? 10.870  -48.189 -149.603 1.00 65.48  ? 435 ALA A O   1 
ATOM 3146 C CB  . ALA A 1 435 ? 9.605   -45.768 -148.325 1.00 58.19  ? 435 ALA A CB  1 
ATOM 3147 N N   . GLY A 1 436 ? 8.701   -48.769 -149.772 1.00 68.84  ? 436 GLY A N   1 
ATOM 3148 C CA  . GLY A 1 436 ? 8.947   -49.696 -150.851 1.00 63.04  ? 436 GLY A CA  1 
ATOM 3149 C C   . GLY A 1 436 ? 9.233   -49.007 -152.165 1.00 67.26  ? 436 GLY A C   1 
ATOM 3150 O O   . GLY A 1 436 ? 9.082   -47.798 -152.318 1.00 75.56  ? 436 GLY A O   1 
ATOM 3151 N N   . ALA A 1 437 ? 9.666   -49.808 -153.130 1.00 56.31  ? 437 ALA A N   1 
ATOM 3152 C CA  . ALA A 1 437 ? 9.873   -49.364 -154.496 1.00 54.64  ? 437 ALA A CA  1 
ATOM 3153 C C   . ALA A 1 437 ? 9.096   -50.272 -155.433 1.00 59.12  ? 437 ALA A C   1 
ATOM 3154 O O   . ALA A 1 437 ? 8.842   -51.437 -155.120 1.00 73.21  ? 437 ALA A O   1 
ATOM 3155 C CB  . ALA A 1 437 ? 11.355  -49.367 -154.866 1.00 55.14  ? 437 ALA A CB  1 
ATOM 3156 N N   . ILE A 1 438 ? 8.713   -49.734 -156.585 1.00 45.88  ? 438 ILE A N   1 
ATOM 3157 C CA  . ILE A 1 438 ? 7.898   -50.452 -157.554 1.00 48.57  ? 438 ILE A CA  1 
ATOM 3158 C C   . ILE A 1 438 ? 8.812   -51.086 -158.589 1.00 52.66  ? 438 ILE A C   1 
ATOM 3159 O O   . ILE A 1 438 ? 9.692   -50.419 -159.141 1.00 67.74  ? 438 ILE A O   1 
ATOM 3160 C CB  . ILE A 1 438 ? 6.877   -49.521 -158.224 1.00 56.13  ? 438 ILE A CB  1 
ATOM 3161 C CG1 . ILE A 1 438 ? 5.920   -48.947 -157.184 1.00 56.45  ? 438 ILE A CG1 1 
ATOM 3162 C CG2 . ILE A 1 438 ? 6.106   -50.263 -159.289 1.00 58.15  ? 438 ILE A CG2 1 
ATOM 3163 C CD1 . ILE A 1 438 ? 4.986   -47.910 -157.743 1.00 59.75  ? 438 ILE A CD1 1 
ATOM 3164 N N   . LEU A 1 439 ? 8.611   -52.376 -158.846 1.00 62.15  ? 439 LEU A N   1 
ATOM 3165 C CA  . LEU A 1 439 ? 9.406   -53.100 -159.822 1.00 63.65  ? 439 LEU A CA  1 
ATOM 3166 C C   . LEU A 1 439 ? 8.589   -53.794 -160.899 1.00 62.28  ? 439 LEU A C   1 
ATOM 3167 O O   . LEU A 1 439 ? 9.162   -54.175 -161.923 1.00 70.87  ? 439 LEU A O   1 
ATOM 3168 C CB  . LEU A 1 439 ? 10.286  -54.147 -159.125 1.00 66.01  ? 439 LEU A CB  1 
ATOM 3169 C CG  . LEU A 1 439 ? 11.286  -53.599 -158.110 1.00 65.36  ? 439 LEU A CG  1 
ATOM 3170 C CD1 . LEU A 1 439 ? 12.045  -54.726 -157.441 1.00 66.46  ? 439 LEU A CD1 1 
ATOM 3171 C CD2 . LEU A 1 439 ? 12.239  -52.638 -158.780 1.00 63.07  ? 439 LEU A CD2 1 
ATOM 3172 N N   . ASP A 1 440 ? 7.285   -53.971 -160.708 1.00 68.06  ? 440 ASP A N   1 
ATOM 3173 C CA  . ASP A 1 440 ? 6.461   -54.626 -161.712 1.00 72.37  ? 440 ASP A CA  1 
ATOM 3174 C C   . ASP A 1 440 ? 5.094   -53.962 -161.763 1.00 78.47  ? 440 ASP A C   1 
ATOM 3175 O O   . ASP A 1 440 ? 4.654   -53.321 -160.807 1.00 79.15  ? 440 ASP A O   1 
ATOM 3176 C CB  . ASP A 1 440 ? 6.320   -56.120 -161.431 1.00 76.43  ? 440 ASP A CB  1 
ATOM 3177 C CG  . ASP A 1 440 ? 7.568   -56.891 -161.779 1.00 86.29  ? 440 ASP A CG  1 
ATOM 3178 O OD1 . ASP A 1 440 ? 7.844   -57.055 -162.985 1.00 82.67  ? 440 ASP A OD1 1 
ATOM 3179 O OD2 . ASP A 1 440 ? 8.276   -57.329 -160.849 1.00 87.06  ? 440 ASP A OD2 1 
ATOM 3180 N N   . VAL A 1 441 ? 4.426   -54.124 -162.900 1.00 66.62  ? 441 VAL A N   1 
ATOM 3181 C CA  . VAL A 1 441 ? 3.151   -53.476 -163.165 1.00 58.41  ? 441 VAL A CA  1 
ATOM 3182 C C   . VAL A 1 441 ? 2.136   -54.526 -163.589 1.00 63.83  ? 441 VAL A C   1 
ATOM 3183 O O   . VAL A 1 441 ? 2.438   -55.403 -164.404 1.00 66.55  ? 441 VAL A O   1 
ATOM 3184 C CB  . VAL A 1 441 ? 3.285   -52.387 -164.247 1.00 59.55  ? 441 VAL A CB  1 
ATOM 3185 C CG1 . VAL A 1 441 ? 2.001   -51.599 -164.365 1.00 68.68  ? 441 VAL A CG1 1 
ATOM 3186 C CG2 . VAL A 1 441 ? 4.439   -51.467 -163.928 1.00 61.64  ? 441 VAL A CG2 1 
ATOM 3187 N N   . ASP A 1 442 ? 0.932   -54.432 -163.034 1.00 72.59  ? 442 ASP A N   1 
ATOM 3188 C CA  . ASP A 1 442 ? -0.198  -55.264 -163.419 1.00 62.92  ? 442 ASP A CA  1 
ATOM 3189 C C   . ASP A 1 442 ? -1.146  -54.419 -164.254 1.00 70.28  ? 442 ASP A C   1 
ATOM 3190 O O   . ASP A 1 442 ? -1.495  -53.304 -163.858 1.00 79.87  ? 442 ASP A O   1 
ATOM 3191 C CB  . ASP A 1 442 ? -0.914  -55.819 -162.183 1.00 74.43  ? 442 ASP A CB  1 
ATOM 3192 C CG  . ASP A 1 442 ? -1.067  -54.780 -161.072 1.00 79.71  ? 442 ASP A CG  1 
ATOM 3193 O OD1 . ASP A 1 442 ? -0.503  -53.676 -161.198 1.00 86.53  ? 442 ASP A OD1 1 
ATOM 3194 O OD2 . ASP A 1 442 ? -1.748  -55.069 -160.065 1.00 64.48  ? 442 ASP A OD2 1 
ATOM 3195 N N   . LEU A 1 443 ? -1.559  -54.938 -165.406 1.00 67.92  ? 443 LEU A N   1 
ATOM 3196 C CA  . LEU A 1 443 ? -2.376  -54.161 -166.325 1.00 66.82  ? 443 LEU A CA  1 
ATOM 3197 C C   . LEU A 1 443 ? -3.548  -54.990 -166.823 1.00 73.67  ? 443 LEU A C   1 
ATOM 3198 O O   . LEU A 1 443 ? -3.499  -56.219 -166.866 1.00 79.65  ? 443 LEU A O   1 
ATOM 3199 C CB  . LEU A 1 443 ? -1.565  -53.662 -167.521 1.00 64.89  ? 443 LEU A CB  1 
ATOM 3200 C CG  . LEU A 1 443 ? -0.881  -52.315 -167.348 1.00 65.13  ? 443 LEU A CG  1 
ATOM 3201 C CD1 . LEU A 1 443 ? 0.191   -52.132 -168.394 1.00 71.87  ? 443 LEU A CD1 1 
ATOM 3202 C CD2 . LEU A 1 443 ? -1.909  -51.218 -167.453 1.00 71.25  ? 443 LEU A CD2 1 
ATOM 3203 N N   . LYS A 1 444 ? -4.605  -54.287 -167.205 1.00 75.60  ? 444 LYS A N   1 
ATOM 3204 C CA  . LYS A 1 444 ? -5.791  -54.864 -167.817 1.00 70.82  ? 444 LYS A CA  1 
ATOM 3205 C C   . LYS A 1 444 ? -6.155  -54.023 -169.038 1.00 73.40  ? 444 LYS A C   1 
ATOM 3206 O O   . LYS A 1 444 ? -5.560  -52.975 -169.291 1.00 83.03  ? 444 LYS A O   1 
ATOM 3207 C CB  . LYS A 1 444 ? -6.935  -54.931 -166.807 1.00 68.48  ? 444 LYS A CB  1 
ATOM 3208 C CG  . LYS A 1 444 ? -6.823  -56.073 -165.814 1.00 73.64  ? 444 LYS A CG  1 
ATOM 3209 C CD  . LYS A 1 444 ? -6.748  -57.419 -166.507 1.00 77.53  ? 444 LYS A CD  1 
ATOM 3210 C CE  . LYS A 1 444 ? -6.261  -58.498 -165.558 1.00 77.09  ? 444 LYS A CE  1 
ATOM 3211 N NZ  . LYS A 1 444 ? -4.777  -58.583 -165.527 1.00 77.94  ? 444 LYS A NZ  1 
ATOM 3212 N N   . GLY A 1 445 ? -7.137  -54.485 -169.801 1.00 63.45  ? 445 GLY A N   1 
ATOM 3213 C CA  . GLY A 1 445 ? -7.539  -53.746 -170.981 1.00 72.56  ? 445 GLY A CA  1 
ATOM 3214 C C   . GLY A 1 445 ? -8.893  -54.156 -171.513 1.00 74.73  ? 445 GLY A C   1 
ATOM 3215 O O   . GLY A 1 445 ? -9.314  -55.298 -171.320 1.00 83.14  ? 445 GLY A O   1 
ATOM 3216 N N   . THR A 1 446 ? -9.591  -53.241 -172.183 1.00 65.84  ? 446 THR A N   1 
ATOM 3217 C CA  . THR A 1 446 ? -10.923 -53.562 -172.672 1.00 69.07  ? 446 THR A CA  1 
ATOM 3218 C C   . THR A 1 446 ? -11.007 -53.536 -174.192 1.00 73.31  ? 446 THR A C   1 
ATOM 3219 O O   . THR A 1 446 ? -11.303 -54.562 -174.809 1.00 82.01  ? 446 THR A O   1 
ATOM 3220 C CB  . THR A 1 446 ? -11.937 -52.595 -172.071 1.00 76.99  ? 446 THR A CB  1 
ATOM 3221 O OG1 . THR A 1 446 ? -11.473 -51.250 -172.244 1.00 72.87  ? 446 THR A OG1 1 
ATOM 3222 C CG2 . THR A 1 446 ? -12.102 -52.873 -170.589 1.00 72.50  ? 446 THR A CG2 1 
ATOM 3223 N N   . VAL A 1 447 ? -10.725 -52.384 -174.802 1.00 61.24  ? 447 VAL A N   1 
ATOM 3224 C CA  . VAL A 1 447 ? -10.750 -52.208 -176.253 1.00 60.81  ? 447 VAL A CA  1 
ATOM 3225 C C   . VAL A 1 447 ? -12.067 -52.672 -176.866 1.00 67.67  ? 447 VAL A C   1 
ATOM 3226 O O   . VAL A 1 447 ? -12.225 -53.850 -177.200 1.00 74.34  ? 447 VAL A O   1 
ATOM 3227 C CB  . VAL A 1 447 ? -9.574  -52.941 -176.914 1.00 59.93  ? 447 VAL A CB  1 
ATOM 3228 C CG1 . VAL A 1 447 ? -9.459  -52.535 -178.366 1.00 65.21  ? 447 VAL A CG1 1 
ATOM 3229 C CG2 . VAL A 1 447 ? -8.294  -52.639 -176.176 1.00 66.25  ? 447 VAL A CG2 1 
ATOM 3230 N N   . ALA A 1 448 ? -13.009 -51.753 -177.045 1.00 60.38  ? 448 ALA A N   1 
ATOM 3231 C CA  . ALA A 1 448 ? -14.278 -52.091 -177.682 1.00 60.25  ? 448 ALA A CA  1 
ATOM 3232 C C   . ALA A 1 448 ? -14.710 -51.021 -178.680 1.00 63.18  ? 448 ALA A C   1 
ATOM 3233 O O   . ALA A 1 448 ? -15.852 -51.008 -179.140 1.00 51.52  ? 448 ALA A O   1 
ATOM 3234 C CB  . ALA A 1 448 ? -15.352 -52.295 -176.637 1.00 56.23  ? 448 ALA A CB  1 
ATOM 3235 N N   . ALA B 2 2   ? -8.261  -35.554 -112.251 1.00 95.80  ? 2   ALA B N   1 
ATOM 3236 C CA  . ALA B 2 2   ? -8.221  -34.733 -111.048 1.00 95.52  ? 2   ALA B CA  1 
ATOM 3237 C C   . ALA B 2 2   ? -7.009  -33.812 -111.058 1.00 97.63  ? 2   ALA B C   1 
ATOM 3238 O O   . ALA B 2 2   ? -7.148  -32.590 -111.052 1.00 97.13  ? 2   ALA B O   1 
ATOM 3239 C CB  . ALA B 2 2   ? -8.212  -35.609 -109.810 1.00 92.40  ? 2   ALA B CB  1 
ATOM 3240 N N   . MET B 2 3   ? -5.819  -34.405 -111.070 1.00 91.33  ? 3   MET B N   1 
ATOM 3241 C CA  . MET B 2 3   ? -4.567  -33.665 -111.100 1.00 86.13  ? 3   MET B CA  1 
ATOM 3242 C C   . MET B 2 3   ? -3.814  -33.994 -112.378 1.00 86.03  ? 3   MET B C   1 
ATOM 3243 O O   . MET B 2 3   ? -3.685  -35.164 -112.749 1.00 92.04  ? 3   MET B O   1 
ATOM 3244 C CB  . MET B 2 3   ? -3.695  -33.995 -109.888 1.00 84.15  ? 3   MET B CB  1 
ATOM 3245 C CG  . MET B 2 3   ? -4.115  -33.304 -108.609 1.00 85.19  ? 3   MET B CG  1 
ATOM 3246 S SD  . MET B 2 3   ? -3.234  -31.760 -108.350 1.00 99.15  ? 3   MET B SD  1 
ATOM 3247 C CE  . MET B 2 3   ? -1.554  -32.357 -108.285 1.00 87.39  ? 3   MET B CE  1 
ATOM 3248 N N   . TYR B 2 4   ? -3.318  -32.960 -113.048 1.00 78.91  ? 4   TYR B N   1 
ATOM 3249 C CA  . TYR B 2 4   ? -2.549  -33.134 -114.266 1.00 81.13  ? 4   TYR B CA  1 
ATOM 3250 C C   . TYR B 2 4   ? -1.066  -33.280 -113.936 1.00 87.03  ? 4   TYR B C   1 
ATOM 3251 O O   . TYR B 2 4   ? -0.647  -33.192 -112.781 1.00 88.19  ? 4   TYR B O   1 
ATOM 3252 C CB  . TYR B 2 4   ? -2.799  -31.965 -115.211 1.00 81.63  ? 4   TYR B CB  1 
ATOM 3253 C CG  . TYR B 2 4   ? -4.147  -32.025 -115.876 1.00 81.54  ? 4   TYR B CG  1 
ATOM 3254 C CD1 . TYR B 2 4   ? -4.798  -33.234 -116.041 1.00 84.10  ? 4   TYR B CD1 1 
ATOM 3255 C CD2 . TYR B 2 4   ? -4.772  -30.878 -116.333 1.00 83.33  ? 4   TYR B CD2 1 
ATOM 3256 C CE1 . TYR B 2 4   ? -6.030  -33.302 -116.647 1.00 86.64  ? 4   TYR B CE1 1 
ATOM 3257 C CE2 . TYR B 2 4   ? -6.006  -30.935 -116.939 1.00 83.12  ? 4   TYR B CE2 1 
ATOM 3258 C CZ  . TYR B 2 4   ? -6.629  -32.151 -117.093 1.00 85.35  ? 4   TYR B CZ  1 
ATOM 3259 O OH  . TYR B 2 4   ? -7.860  -32.226 -117.696 1.00 87.45  ? 4   TYR B OH  1 
ATOM 3260 N N   . GLN B 2 5   ? -0.258  -33.509 -114.967 1.00 83.31  ? 5   GLN B N   1 
ATOM 3261 C CA  . GLN B 2 5   ? 1.167   -33.731 -114.764 1.00 81.72  ? 5   GLN B CA  1 
ATOM 3262 C C   . GLN B 2 5   ? 1.851   -32.475 -114.247 1.00 83.59  ? 5   GLN B C   1 
ATOM 3263 O O   . GLN B 2 5   ? 1.568   -31.363 -114.696 1.00 87.56  ? 5   GLN B O   1 
ATOM 3264 C CB  . GLN B 2 5   ? 1.825   -34.171 -116.067 1.00 81.38  ? 5   GLN B CB  1 
ATOM 3265 C CG  . GLN B 2 5   ? 1.395   -35.534 -116.545 1.00 85.45  ? 5   GLN B CG  1 
ATOM 3266 C CD  . GLN B 2 5   ? 2.131   -36.646 -115.835 1.00 89.76  ? 5   GLN B CD  1 
ATOM 3267 O OE1 . GLN B 2 5   ? 2.868   -36.404 -114.881 1.00 88.49  ? 5   GLN B OE1 1 
ATOM 3268 N NE2 . GLN B 2 5   ? 1.935   -37.873 -116.298 1.00 88.86  ? 5   GLN B NE2 1 
ATOM 3269 N N   . GLN B 2 6   ? 2.763   -32.662 -113.300 1.00 79.35  ? 6   GLN B N   1 
ATOM 3270 C CA  . GLN B 2 6   ? 3.585   -31.560 -112.831 1.00 78.92  ? 6   GLN B CA  1 
ATOM 3271 C C   . GLN B 2 6   ? 4.501   -31.084 -113.944 1.00 77.63  ? 6   GLN B C   1 
ATOM 3272 O O   . GLN B 2 6   ? 4.944   -31.866 -114.786 1.00 89.90  ? 6   GLN B O   1 
ATOM 3273 C CB  . GLN B 2 6   ? 4.433   -31.983 -111.639 1.00 72.66  ? 6   GLN B CB  1 
ATOM 3274 C CG  . GLN B 2 6   ? 3.823   -33.059 -110.796 1.00 78.57  ? 6   GLN B CG  1 
ATOM 3275 C CD  . GLN B 2 6   ? 4.743   -33.471 -109.683 1.00 81.82  ? 6   GLN B CD  1 
ATOM 3276 O OE1 . GLN B 2 6   ? 5.825   -32.912 -109.525 1.00 79.05  ? 6   GLN B OE1 1 
ATOM 3277 N NE2 . GLN B 2 6   ? 4.328   -34.460 -108.908 1.00 86.28  ? 6   GLN B NE2 1 
ATOM 3278 N N   . TYR B 2 7   ? 4.787   -29.795 -113.945 1.00 62.16  ? 7   TYR B N   1 
ATOM 3279 C CA  . TYR B 2 7   ? 5.668   -29.188 -114.930 1.00 61.26  ? 7   TYR B CA  1 
ATOM 3280 C C   . TYR B 2 7   ? 6.878   -28.628 -114.199 1.00 74.82  ? 7   TYR B C   1 
ATOM 3281 O O   . TYR B 2 7   ? 6.773   -27.613 -113.505 1.00 88.42  ? 7   TYR B O   1 
ATOM 3282 C CB  . TYR B 2 7   ? 4.933   -28.101 -115.705 1.00 68.84  ? 7   TYR B CB  1 
ATOM 3283 C CG  . TYR B 2 7   ? 5.832   -27.114 -116.400 1.00 73.51  ? 7   TYR B CG  1 
ATOM 3284 C CD1 . TYR B 2 7   ? 6.595   -27.486 -117.491 1.00 71.63  ? 7   TYR B CD1 1 
ATOM 3285 C CD2 . TYR B 2 7   ? 5.910   -25.805 -115.966 1.00 77.95  ? 7   TYR B CD2 1 
ATOM 3286 C CE1 . TYR B 2 7   ? 7.410   -26.580 -118.124 1.00 73.89  ? 7   TYR B CE1 1 
ATOM 3287 C CE2 . TYR B 2 7   ? 6.720   -24.897 -116.593 1.00 72.80  ? 7   TYR B CE2 1 
ATOM 3288 C CZ  . TYR B 2 7   ? 7.468   -25.288 -117.667 1.00 72.25  ? 7   TYR B CZ  1 
ATOM 3289 O OH  . TYR B 2 7   ? 8.277   -24.375 -118.289 1.00 79.48  ? 7   TYR B OH  1 
ATOM 3290 N N   . SER B 2 8   ? 8.019   -29.292 -114.339 1.00 73.70  ? 8   SER B N   1 
ATOM 3291 C CA  . SER B 2 8   ? 9.252   -28.824 -113.720 1.00 67.67  ? 8   SER B CA  1 
ATOM 3292 C C   . SER B 2 8   ? 10.181  -28.301 -114.799 1.00 72.47  ? 8   SER B C   1 
ATOM 3293 O O   . SER B 2 8   ? 10.672  -29.091 -115.618 1.00 80.74  ? 8   SER B O   1 
ATOM 3294 C CB  . SER B 2 8   ? 9.930   -29.946 -112.938 1.00 70.58  ? 8   SER B CB  1 
ATOM 3295 O OG  . SER B 2 8   ? 9.957   -31.139 -113.696 1.00 79.11  ? 8   SER B OG  1 
ATOM 3296 N N   . PRO B 2 9   ? 10.455  -26.997 -114.850 1.00 73.38  ? 9   PRO B N   1 
ATOM 3297 C CA  . PRO B 2 9   ? 11.328  -26.469 -115.905 1.00 72.22  ? 9   PRO B CA  1 
ATOM 3298 C C   . PRO B 2 9   ? 12.779  -26.877 -115.765 1.00 75.22  ? 9   PRO B C   1 
ATOM 3299 O O   . PRO B 2 9   ? 13.540  -26.707 -116.722 1.00 80.09  ? 9   PRO B O   1 
ATOM 3300 C CB  . PRO B 2 9   ? 11.170  -24.949 -115.780 1.00 65.71  ? 9   PRO B CB  1 
ATOM 3301 C CG  . PRO B 2 9   ? 10.326  -24.701 -114.585 1.00 72.25  ? 9   PRO B CG  1 
ATOM 3302 C CD  . PRO B 2 9   ? 10.064  -25.974 -113.873 1.00 75.69  ? 9   PRO B CD  1 
ATOM 3303 N N   . LYS B 2 10  ? 13.196  -27.401 -114.615 1.00 79.31  ? 10  LYS B N   1 
ATOM 3304 C CA  . LYS B 2 10  ? 14.578  -27.834 -114.469 1.00 78.77  ? 10  LYS B CA  1 
ATOM 3305 C C   . LYS B 2 10  ? 14.846  -29.164 -115.156 1.00 79.52  ? 10  LYS B C   1 
ATOM 3306 O O   . LYS B 2 10  ? 16.007  -29.479 -115.430 1.00 82.17  ? 10  LYS B O   1 
ATOM 3307 C CB  . LYS B 2 10  ? 14.950  -27.924 -112.989 1.00 75.93  ? 10  LYS B CB  1 
ATOM 3308 C CG  . LYS B 2 10  ? 15.050  -29.331 -112.443 1.00 80.44  ? 10  LYS B CG  1 
ATOM 3309 C CD  . LYS B 2 10  ? 15.073  -29.318 -110.927 1.00 84.31  ? 10  LYS B CD  1 
ATOM 3310 C CE  . LYS B 2 10  ? 15.320  -30.705 -110.364 1.00 85.12  ? 10  LYS B CE  1 
ATOM 3311 N NZ  . LYS B 2 10  ? 15.927  -30.648 -109.008 1.00 82.96  ? 10  LYS B NZ  1 
ATOM 3312 N N   . ASP B 2 11  ? 13.807  -29.939 -115.450 1.00 83.40  ? 11  ASP B N   1 
ATOM 3313 C CA  . ASP B 2 11  ? 13.956  -31.225 -116.114 1.00 83.90  ? 11  ASP B CA  1 
ATOM 3314 C C   . ASP B 2 11  ? 13.876  -31.125 -117.629 1.00 84.01  ? 11  ASP B C   1 
ATOM 3315 O O   . ASP B 2 11  ? 14.056  -32.138 -118.309 1.00 86.94  ? 11  ASP B O   1 
ATOM 3316 C CB  . ASP B 2 11  ? 12.888  -32.201 -115.620 1.00 84.47  ? 11  ASP B CB  1 
ATOM 3317 C CG  . ASP B 2 11  ? 13.305  -32.932 -114.363 1.00 89.52  ? 11  ASP B CG  1 
ATOM 3318 O OD1 . ASP B 2 11  ? 14.027  -32.333 -113.541 1.00 89.01  ? 11  ASP B OD1 1 
ATOM 3319 O OD2 . ASP B 2 11  ? 12.911  -34.104 -114.198 1.00 93.71  ? 11  ASP B OD2 1 
ATOM 3320 N N   . VAL B 2 12  ? 13.611  -29.943 -118.172 1.00 79.74  ? 12  VAL B N   1 
ATOM 3321 C CA  . VAL B 2 12  ? 13.493  -29.773 -119.615 1.00 79.84  ? 12  VAL B CA  1 
ATOM 3322 C C   . VAL B 2 12  ? 14.886  -29.600 -120.200 1.00 80.91  ? 12  VAL B C   1 
ATOM 3323 O O   . VAL B 2 12  ? 15.619  -28.682 -119.820 1.00 82.50  ? 12  VAL B O   1 
ATOM 3324 C CB  . VAL B 2 12  ? 12.599  -28.577 -119.959 1.00 75.37  ? 12  VAL B CB  1 
ATOM 3325 C CG1 . VAL B 2 12  ? 12.555  -28.373 -121.453 1.00 74.59  ? 12  VAL B CG1 1 
ATOM 3326 C CG2 . VAL B 2 12  ? 11.207  -28.790 -119.410 1.00 74.45  ? 12  VAL B CG2 1 
ATOM 3327 N N   . VAL B 2 13  ? 15.252  -30.476 -121.128 1.00 79.08  ? 13  VAL B N   1 
ATOM 3328 C CA  . VAL B 2 13  ? 16.569  -30.467 -121.747 1.00 77.23  ? 13  VAL B CA  1 
ATOM 3329 C C   . VAL B 2 13  ? 16.395  -30.377 -123.253 1.00 80.56  ? 13  VAL B C   1 
ATOM 3330 O O   . VAL B 2 13  ? 15.680  -31.190 -123.847 1.00 87.78  ? 13  VAL B O   1 
ATOM 3331 C CB  . VAL B 2 13  ? 17.376  -31.722 -121.374 1.00 78.31  ? 13  VAL B CB  1 
ATOM 3332 C CG1 . VAL B 2 13  ? 18.582  -31.850 -122.270 1.00 80.58  ? 13  VAL B CG1 1 
ATOM 3333 C CG2 . VAL B 2 13  ? 17.791  -31.663 -119.922 1.00 79.76  ? 13  VAL B CG2 1 
ATOM 3334 N N   . CYS B 2 14  ? 17.048  -29.400 -123.869 1.00 78.54  ? 14  CYS B N   1 
ATOM 3335 C CA  . CYS B 2 14  ? 17.014  -29.216 -125.311 1.00 78.62  ? 14  CYS B CA  1 
ATOM 3336 C C   . CYS B 2 14  ? 18.395  -29.505 -125.875 1.00 83.67  ? 14  CYS B C   1 
ATOM 3337 O O   . CYS B 2 14  ? 19.396  -29.012 -125.349 1.00 88.49  ? 14  CYS B O   1 
ATOM 3338 C CB  . CYS B 2 14  ? 16.582  -27.797 -125.672 1.00 79.44  ? 14  CYS B CB  1 
ATOM 3339 S SG  . CYS B 2 14  ? 15.038  -27.279 -124.911 1.00 108.01 ? 14  CYS B SG  1 
ATOM 3340 N N   . SER B 2 15  ? 18.452  -30.302 -126.934 1.00 72.31  ? 15  SER B N   1 
ATOM 3341 C CA  . SER B 2 15  ? 19.719  -30.704 -127.524 1.00 67.54  ? 15  SER B CA  1 
ATOM 3342 C C   . SER B 2 15  ? 19.664  -30.560 -129.033 1.00 68.71  ? 15  SER B C   1 
ATOM 3343 O O   . SER B 2 15  ? 18.718  -31.020 -129.674 1.00 75.51  ? 15  SER B O   1 
ATOM 3344 C CB  . SER B 2 15  ? 20.059  -32.141 -127.165 1.00 74.14  ? 15  SER B CB  1 
ATOM 3345 O OG  . SER B 2 15  ? 20.868  -32.719 -128.169 1.00 79.91  ? 15  SER B OG  1 
ATOM 3346 N N   . TRP B 2 16  ? 20.694  -29.936 -129.596 1.00 61.47  ? 16  TRP B N   1 
ATOM 3347 C CA  . TRP B 2 16  ? 20.797  -29.722 -131.030 1.00 65.81  ? 16  TRP B CA  1 
ATOM 3348 C C   . TRP B 2 16  ? 22.233  -29.932 -131.472 1.00 68.77  ? 16  TRP B C   1 
ATOM 3349 O O   . TRP B 2 16  ? 23.163  -29.500 -130.789 1.00 75.85  ? 16  TRP B O   1 
ATOM 3350 C CB  . TRP B 2 16  ? 20.353  -28.315 -131.419 1.00 67.69  ? 16  TRP B CB  1 
ATOM 3351 C CG  . TRP B 2 16  ? 20.520  -28.031 -132.866 1.00 64.40  ? 16  TRP B CG  1 
ATOM 3352 C CD1 . TRP B 2 16  ? 19.846  -28.606 -133.891 1.00 64.53  ? 16  TRP B CD1 1 
ATOM 3353 C CD2 . TRP B 2 16  ? 21.434  -27.103 -133.456 1.00 69.46  ? 16  TRP B CD2 1 
ATOM 3354 N NE1 . TRP B 2 16  ? 20.274  -28.093 -135.086 1.00 64.87  ? 16  TRP B NE1 1 
ATOM 3355 C CE2 . TRP B 2 16  ? 21.250  -27.166 -134.844 1.00 70.42  ? 16  TRP B CE2 1 
ATOM 3356 C CE3 . TRP B 2 16  ? 22.387  -26.224 -132.943 1.00 71.69  ? 16  TRP B CE3 1 
ATOM 3357 C CZ2 . TRP B 2 16  ? 21.985  -26.386 -135.726 1.00 68.06  ? 16  TRP B CZ2 1 
ATOM 3358 C CZ3 . TRP B 2 16  ? 23.113  -25.452 -133.818 1.00 66.12  ? 16  TRP B CZ3 1 
ATOM 3359 C CH2 . TRP B 2 16  ? 22.909  -25.538 -135.193 1.00 65.09  ? 16  TRP B CH2 1 
ATOM 3360 N N   . ASN B 2 17  ? 22.408  -30.589 -132.616 1.00 71.85  ? 17  ASN B N   1 
ATOM 3361 C CA  . ASN B 2 17  ? 23.727  -30.767 -133.224 1.00 73.58  ? 17  ASN B CA  1 
ATOM 3362 C C   . ASN B 2 17  ? 24.706  -31.437 -132.270 1.00 79.10  ? 17  ASN B C   1 
ATOM 3363 O O   . ASN B 2 17  ? 25.893  -31.109 -132.235 1.00 74.56  ? 17  ASN B O   1 
ATOM 3364 C CB  . ASN B 2 17  ? 24.291  -29.435 -133.707 1.00 70.10  ? 17  ASN B CB  1 
ATOM 3365 C CG  . ASN B 2 17  ? 25.282  -29.601 -134.828 1.00 76.36  ? 17  ASN B CG  1 
ATOM 3366 O OD1 . ASN B 2 17  ? 24.930  -30.024 -135.927 1.00 81.88  ? 17  ASN B OD1 1 
ATOM 3367 N ND2 . ASN B 2 17  ? 26.538  -29.291 -134.551 1.00 73.11  ? 17  ASN B ND2 1 
ATOM 3368 N N   . GLY B 2 18  ? 24.208  -32.376 -131.476 1.00 78.43  ? 18  GLY B N   1 
ATOM 3369 C CA  . GLY B 2 18  ? 25.066  -33.132 -130.594 1.00 70.84  ? 18  GLY B CA  1 
ATOM 3370 C C   . GLY B 2 18  ? 25.477  -32.424 -129.324 1.00 73.34  ? 18  GLY B C   1 
ATOM 3371 O O   . GLY B 2 18  ? 26.218  -33.008 -128.527 1.00 80.75  ? 18  GLY B O   1 
ATOM 3372 N N   . ILE B 2 19  ? 25.033  -31.194 -129.106 1.00 73.68  ? 19  ILE B N   1 
ATOM 3373 C CA  . ILE B 2 19  ? 25.309  -30.480 -127.871 1.00 69.36  ? 19  ILE B CA  1 
ATOM 3374 C C   . ILE B 2 19  ? 23.987  -30.225 -127.171 1.00 70.51  ? 19  ILE B C   1 
ATOM 3375 O O   . ILE B 2 19  ? 22.915  -30.261 -127.776 1.00 79.50  ? 19  ILE B O   1 
ATOM 3376 C CB  . ILE B 2 19  ? 26.058  -29.155 -128.105 1.00 70.25  ? 19  ILE B CB  1 
ATOM 3377 C CG1 . ILE B 2 19  ? 25.152  -28.155 -128.814 1.00 70.72  ? 19  ILE B CG1 1 
ATOM 3378 C CG2 . ILE B 2 19  ? 27.306  -29.393 -128.922 1.00 73.63  ? 19  ILE B CG2 1 
ATOM 3379 C CD1 . ILE B 2 19  ? 25.509  -26.724 -128.558 1.00 69.54  ? 19  ILE B CD1 1 
ATOM 3380 N N   . ALA B 2 20  ? 24.067  -29.969 -125.872 1.00 69.78  ? 20  ALA B N   1 
ATOM 3381 C CA  . ALA B 2 20  ? 22.894  -29.674 -125.067 1.00 74.26  ? 20  ALA B CA  1 
ATOM 3382 C C   . ALA B 2 20  ? 22.881  -28.195 -124.725 1.00 77.06  ? 20  ALA B C   1 
ATOM 3383 O O   . ALA B 2 20  ? 23.876  -27.659 -124.232 1.00 78.01  ? 20  ALA B O   1 
ATOM 3384 C CB  . ALA B 2 20  ? 22.871  -30.511 -123.792 1.00 71.98  ? 20  ALA B CB  1 
ATOM 3385 N N   . ILE B 2 21  ? 21.751  -27.546 -124.983 1.00 77.68  ? 21  ILE B N   1 
ATOM 3386 C CA  . ILE B 2 21  ? 21.595  -26.118 -124.751 1.00 75.58  ? 21  ILE B CA  1 
ATOM 3387 C C   . ILE B 2 21  ? 21.118  -25.950 -123.314 1.00 75.78  ? 21  ILE B C   1 
ATOM 3388 O O   . ILE B 2 21  ? 19.970  -26.248 -122.988 1.00 76.94  ? 21  ILE B O   1 
ATOM 3389 C CB  . ILE B 2 21  ? 20.625  -25.493 -125.753 1.00 70.23  ? 21  ILE B CB  1 
ATOM 3390 C CG1 . ILE B 2 21  ? 21.047  -25.855 -127.174 1.00 66.66  ? 21  ILE B CG1 1 
ATOM 3391 C CG2 . ILE B 2 21  ? 20.587  -24.001 -125.581 1.00 71.06  ? 21  ILE B CG2 1 
ATOM 3392 C CD1 . ILE B 2 21  ? 20.607  -24.869 -128.216 1.00 74.02  ? 21  ILE B CD1 1 
ATOM 3393 N N   . GLU B 2 22  ? 22.005  -25.469 -122.451 1.00 79.92  ? 22  GLU B N   1 
ATOM 3394 C CA  . GLU B 2 22  ? 21.744  -25.385 -121.023 1.00 81.88  ? 22  GLU B CA  1 
ATOM 3395 C C   . GLU B 2 22  ? 21.754  -23.938 -120.561 1.00 83.37  ? 22  GLU B C   1 
ATOM 3396 O O   . GLU B 2 22  ? 22.459  -23.094 -121.117 1.00 86.31  ? 22  GLU B O   1 
ATOM 3397 C CB  . GLU B 2 22  ? 22.777  -26.172 -120.222 1.00 86.05  ? 22  GLU B CB  1 
ATOM 3398 C CG  . GLU B 2 22  ? 22.400  -27.612 -119.958 1.00 85.48  ? 22  GLU B CG  1 
ATOM 3399 C CD  . GLU B 2 22  ? 23.512  -28.372 -119.272 1.00 91.52  ? 22  GLU B CD  1 
ATOM 3400 O OE1 . GLU B 2 22  ? 24.332  -28.994 -119.978 1.00 94.51  ? 22  GLU B OE1 1 
ATOM 3401 O OE2 . GLU B 2 22  ? 23.571  -28.343 -118.026 1.00 90.43  ? 22  GLU B OE2 1 
ATOM 3402 N N   . GLY B 2 23  ? 20.956  -23.661 -119.538 1.00 72.37  ? 23  GLY B N   1 
ATOM 3403 C CA  . GLY B 2 23  ? 20.897  -22.337 -118.962 1.00 68.79  ? 23  GLY B CA  1 
ATOM 3404 C C   . GLY B 2 23  ? 19.800  -21.537 -119.616 1.00 74.64  ? 23  GLY B C   1 
ATOM 3405 O O   . GLY B 2 23  ? 19.974  -21.054 -120.735 1.00 82.57  ? 23  GLY B O   1 
ATOM 3406 N N   . PHE B 2 24  ? 18.674  -21.374 -118.937 1.00 70.84  ? 24  PHE B N   1 
ATOM 3407 C CA  . PHE B 2 24  ? 17.497  -20.769 -119.534 1.00 71.32  ? 24  PHE B CA  1 
ATOM 3408 C C   . PHE B 2 24  ? 17.242  -19.396 -118.933 1.00 75.96  ? 24  PHE B C   1 
ATOM 3409 O O   . PHE B 2 24  ? 17.614  -19.123 -117.790 1.00 80.64  ? 24  PHE B O   1 
ATOM 3410 C CB  . PHE B 2 24  ? 16.270  -21.652 -119.335 1.00 74.88  ? 24  PHE B CB  1 
ATOM 3411 C CG  . PHE B 2 24  ? 16.346  -22.963 -120.053 1.00 77.24  ? 24  PHE B CG  1 
ATOM 3412 C CD1 . PHE B 2 24  ? 16.570  -23.008 -121.412 1.00 72.25  ? 24  PHE B CD1 1 
ATOM 3413 C CD2 . PHE B 2 24  ? 16.182  -24.149 -119.369 1.00 75.95  ? 24  PHE B CD2 1 
ATOM 3414 C CE1 . PHE B 2 24  ? 16.637  -24.209 -122.071 1.00 72.15  ? 24  PHE B CE1 1 
ATOM 3415 C CE2 . PHE B 2 24  ? 16.246  -25.351 -120.024 1.00 72.68  ? 24  PHE B CE2 1 
ATOM 3416 C CZ  . PHE B 2 24  ? 16.474  -25.381 -121.376 1.00 74.75  ? 24  PHE B CZ  1 
ATOM 3417 N N   . ALA B 2 25  ? 16.598  -18.540 -119.715 1.00 74.90  ? 25  ALA B N   1 
ATOM 3418 C CA  . ALA B 2 25  ? 16.291  -17.199 -119.255 1.00 76.16  ? 25  ALA B CA  1 
ATOM 3419 C C   . ALA B 2 25  ? 15.312  -17.261 -118.086 1.00 78.21  ? 25  ALA B C   1 
ATOM 3420 O O   . ALA B 2 25  ? 14.561  -18.230 -117.948 1.00 80.80  ? 25  ALA B O   1 
ATOM 3421 C CB  . ALA B 2 25  ? 15.704  -16.369 -120.391 1.00 72.04  ? 25  ALA B CB  1 
ATOM 3422 N N   . PRO B 2 26  ? 15.311  -16.250 -117.217 1.00 75.78  ? 26  PRO B N   1 
ATOM 3423 C CA  . PRO B 2 26  ? 14.459  -16.322 -116.019 1.00 74.65  ? 26  PRO B CA  1 
ATOM 3424 C C   . PRO B 2 26  ? 12.973  -16.454 -116.307 1.00 77.79  ? 26  PRO B C   1 
ATOM 3425 O O   . PRO B 2 26  ? 12.265  -17.084 -115.513 1.00 81.43  ? 26  PRO B O   1 
ATOM 3426 C CB  . PRO B 2 26  ? 14.765  -15.011 -115.281 1.00 70.79  ? 26  PRO B CB  1 
ATOM 3427 C CG  . PRO B 2 26  ? 15.624  -14.208 -116.178 1.00 71.41  ? 26  PRO B CG  1 
ATOM 3428 C CD  . PRO B 2 26  ? 16.218  -15.094 -117.201 1.00 71.37  ? 26  PRO B CD  1 
ATOM 3429 N N   . ASP B 2 27  ? 12.465  -15.890 -117.402 1.00 88.55  ? 27  ASP B N   1 
ATOM 3430 C CA  . ASP B 2 27  ? 11.024  -15.791 -117.595 1.00 88.31  ? 27  ASP B CA  1 
ATOM 3431 C C   . ASP B 2 27  ? 10.504  -16.694 -118.705 1.00 88.37  ? 27  ASP B C   1 
ATOM 3432 O O   . ASP B 2 27  ? 9.637   -17.534 -118.457 1.00 94.32  ? 27  ASP B O   1 
ATOM 3433 C CB  . ASP B 2 27  ? 10.639  -14.336 -117.876 1.00 91.05  ? 27  ASP B CB  1 
ATOM 3434 C CG  . ASP B 2 27  ? 10.034  -13.658 -116.669 1.00 99.11  ? 27  ASP B CG  1 
ATOM 3435 O OD1 . ASP B 2 27  ? 9.103   -14.234 -116.069 1.00 99.74  ? 27  ASP B OD1 1 
ATOM 3436 O OD2 . ASP B 2 27  ? 10.489  -12.550 -116.318 1.00 103.88 ? 27  ASP B OD2 1 
ATOM 3437 N N   . SER B 2 28  ? 11.002  -16.549 -119.927 1.00 76.32  ? 28  SER B N   1 
ATOM 3438 C CA  . SER B 2 28  ? 10.520  -17.350 -121.043 1.00 79.98  ? 28  SER B CA  1 
ATOM 3439 C C   . SER B 2 28  ? 11.716  -17.849 -121.831 1.00 80.32  ? 28  SER B C   1 
ATOM 3440 O O   . SER B 2 28  ? 12.581  -17.055 -122.205 1.00 90.21  ? 28  SER B O   1 
ATOM 3441 C CB  . SER B 2 28  ? 9.587   -16.537 -121.943 1.00 80.17  ? 28  SER B CB  1 
ATOM 3442 O OG  . SER B 2 28  ? 9.045   -17.344 -122.969 1.00 83.68  ? 28  SER B OG  1 
ATOM 3443 N N   . PHE B 2 29  ? 11.763  -19.153 -122.094 1.00 59.99  ? 29  PHE B N   1 
ATOM 3444 C CA  . PHE B 2 29  ? 12.968  -19.748 -122.645 1.00 64.94  ? 29  PHE B CA  1 
ATOM 3445 C C   . PHE B 2 29  ? 12.742  -20.706 -123.802 1.00 73.42  ? 29  PHE B C   1 
ATOM 3446 O O   . PHE B 2 29  ? 13.702  -21.351 -124.232 1.00 81.57  ? 29  PHE B O   1 
ATOM 3447 C CB  . PHE B 2 29  ? 13.748  -20.484 -121.550 1.00 68.60  ? 29  PHE B CB  1 
ATOM 3448 C CG  . PHE B 2 29  ? 12.970  -21.566 -120.873 1.00 72.75  ? 29  PHE B CG  1 
ATOM 3449 C CD1 . PHE B 2 29  ? 12.166  -21.283 -119.790 1.00 71.62  ? 29  PHE B CD1 1 
ATOM 3450 C CD2 . PHE B 2 29  ? 13.054  -22.869 -121.311 1.00 69.64  ? 29  PHE B CD2 1 
ATOM 3451 C CE1 . PHE B 2 29  ? 11.457  -22.277 -119.168 1.00 69.23  ? 29  PHE B CE1 1 
ATOM 3452 C CE2 . PHE B 2 29  ? 12.345  -23.863 -120.690 1.00 69.61  ? 29  PHE B CE2 1 
ATOM 3453 C CZ  . PHE B 2 29  ? 11.547  -23.568 -119.619 1.00 72.69  ? 29  PHE B CZ  1 
ATOM 3454 N N   . LEU B 2 30  ? 11.523  -20.833 -124.315 1.00 70.63  ? 30  LEU B N   1 
ATOM 3455 C CA  . LEU B 2 30  ? 11.294  -21.703 -125.461 1.00 65.12  ? 30  LEU B CA  1 
ATOM 3456 C C   . LEU B 2 30  ? 9.962   -21.344 -126.091 1.00 69.31  ? 30  LEU B C   1 
ATOM 3457 O O   . LEU B 2 30  ? 8.965   -21.191 -125.384 1.00 75.98  ? 30  LEU B O   1 
ATOM 3458 C CB  . LEU B 2 30  ? 11.310  -23.174 -125.053 1.00 59.39  ? 30  LEU B CB  1 
ATOM 3459 C CG  . LEU B 2 30  ? 11.222  -24.177 -126.194 1.00 64.56  ? 30  LEU B CG  1 
ATOM 3460 C CD1 . LEU B 2 30  ? 12.524  -24.217 -126.950 1.00 69.06  ? 30  LEU B CD1 1 
ATOM 3461 C CD2 . LEU B 2 30  ? 10.895  -25.540 -125.644 1.00 68.88  ? 30  LEU B CD2 1 
ATOM 3462 N N   . ARG B 2 31  ? 9.950   -21.218 -127.413 1.00 70.36  ? 31  ARG B N   1 
ATOM 3463 C CA  . ARG B 2 31  ? 8.747   -20.849 -128.145 1.00 67.16  ? 31  ARG B CA  1 
ATOM 3464 C C   . ARG B 2 31  ? 8.749   -21.580 -129.475 1.00 70.24  ? 31  ARG B C   1 
ATOM 3465 O O   . ARG B 2 31  ? 9.638   -21.363 -130.300 1.00 76.17  ? 31  ARG B O   1 
ATOM 3466 C CB  . ARG B 2 31  ? 8.683   -19.338 -128.364 1.00 67.07  ? 31  ARG B CB  1 
ATOM 3467 C CG  . ARG B 2 31  ? 8.125   -18.571 -127.191 1.00 71.47  ? 31  ARG B CG  1 
ATOM 3468 C CD  . ARG B 2 31  ? 8.450   -17.094 -127.285 1.00 67.78  ? 31  ARG B CD  1 
ATOM 3469 N NE  . ARG B 2 31  ? 9.485   -16.700 -126.340 1.00 73.77  ? 31  ARG B NE  1 
ATOM 3470 C CZ  . ARG B 2 31  ? 10.705  -16.315 -126.684 1.00 76.82  ? 31  ARG B CZ  1 
ATOM 3471 N NH1 . ARG B 2 31  ? 11.074  -16.244 -127.951 1.00 74.61  ? 31  ARG B NH1 1 
ATOM 3472 N NH2 . ARG B 2 31  ? 11.574  -15.985 -125.734 1.00 74.99  ? 31  ARG B NH2 1 
ATOM 3473 N N   . LEU B 2 32  ? 7.760   -22.439 -129.686 1.00 73.95  ? 32  LEU B N   1 
ATOM 3474 C CA  . LEU B 2 32  ? 7.612   -23.170 -130.935 1.00 74.76  ? 32  LEU B CA  1 
ATOM 3475 C C   . LEU B 2 32  ? 6.346   -22.704 -131.634 1.00 78.30  ? 32  LEU B C   1 
ATOM 3476 O O   . LEU B 2 32  ? 5.290   -22.595 -131.005 1.00 86.04  ? 32  LEU B O   1 
ATOM 3477 C CB  . LEU B 2 32  ? 7.549   -24.675 -130.688 1.00 76.31  ? 32  LEU B CB  1 
ATOM 3478 C CG  . LEU B 2 32  ? 8.497   -25.214 -129.626 1.00 75.61  ? 32  LEU B CG  1 
ATOM 3479 C CD1 . LEU B 2 32  ? 8.265   -26.690 -129.434 1.00 76.30  ? 32  LEU B CD1 1 
ATOM 3480 C CD2 . LEU B 2 32  ? 9.916   -24.952 -130.026 1.00 69.23  ? 32  LEU B CD2 1 
ATOM 3481 N N   . GLN B 2 33  ? 6.453   -22.435 -132.930 1.00 70.06  ? 33  GLN B N   1 
ATOM 3482 C CA  . GLN B 2 33  ? 5.327   -21.903 -133.678 1.00 76.77  ? 33  GLN B CA  1 
ATOM 3483 C C   . GLN B 2 33  ? 5.487   -22.281 -135.139 1.00 78.18  ? 33  GLN B C   1 
ATOM 3484 O O   . GLN B 2 33  ? 6.561   -22.100 -135.713 1.00 79.04  ? 33  GLN B O   1 
ATOM 3485 C CB  . GLN B 2 33  ? 5.238   -20.381 -133.524 1.00 76.47  ? 33  GLN B CB  1 
ATOM 3486 C CG  . GLN B 2 33  ? 3.944   -19.766 -134.028 1.00 77.52  ? 33  GLN B CG  1 
ATOM 3487 C CD  . GLN B 2 33  ? 2.823   -19.820 -133.004 1.00 86.39  ? 33  GLN B CD  1 
ATOM 3488 O OE1 . GLN B 2 33  ? 3.064   -19.991 -131.809 1.00 86.48  ? 33  GLN B OE1 1 
ATOM 3489 N NE2 . GLN B 2 33  ? 1.588   -19.674 -133.471 1.00 85.15  ? 33  GLN B NE2 1 
ATOM 3490 N N   . ARG B 2 34  ? 4.422   -22.812 -135.730 1.00 67.73  ? 34  ARG B N   1 
ATOM 3491 C CA  . ARG B 2 34  ? 4.414   -23.085 -137.157 1.00 70.48  ? 34  ARG B CA  1 
ATOM 3492 C C   . ARG B 2 34  ? 4.203   -21.794 -137.933 1.00 77.02  ? 34  ARG B C   1 
ATOM 3493 O O   . ARG B 2 34  ? 3.455   -20.913 -137.505 1.00 80.45  ? 34  ARG B O   1 
ATOM 3494 C CB  . ARG B 2 34  ? 3.318   -24.086 -137.505 1.00 65.04  ? 34  ARG B CB  1 
ATOM 3495 C CG  . ARG B 2 34  ? 3.649   -25.505 -137.132 1.00 68.91  ? 34  ARG B CG  1 
ATOM 3496 C CD  . ARG B 2 34  ? 2.692   -26.471 -137.786 1.00 66.74  ? 34  ARG B CD  1 
ATOM 3497 N NE  . ARG B 2 34  ? 2.984   -27.847 -137.412 1.00 69.77  ? 34  ARG B NE  1 
ATOM 3498 C CZ  . ARG B 2 34  ? 2.822   -28.886 -138.215 1.00 68.53  ? 34  ARG B CZ  1 
ATOM 3499 N NH1 . ARG B 2 34  ? 2.359   -28.741 -139.442 1.00 68.75  ? 34  ARG B NH1 1 
ATOM 3500 N NH2 . ARG B 2 34  ? 3.126   -30.101 -137.774 1.00 72.48  ? 34  ARG B NH2 1 
ATOM 3501 N N   . THR B 2 35  ? 4.866   -21.685 -139.082 1.00 73.79  ? 35  THR B N   1 
ATOM 3502 C CA  . THR B 2 35  ? 4.792   -20.448 -139.846 1.00 74.26  ? 35  THR B CA  1 
ATOM 3503 C C   . THR B 2 35  ? 3.469   -20.282 -140.575 1.00 72.81  ? 35  THR B C   1 
ATOM 3504 O O   . THR B 2 35  ? 3.161   -19.170 -141.014 1.00 77.03  ? 35  THR B O   1 
ATOM 3505 C CB  . THR B 2 35  ? 5.933   -20.379 -140.855 1.00 72.32  ? 35  THR B CB  1 
ATOM 3506 O OG1 . THR B 2 35  ? 5.646   -21.251 -141.952 1.00 80.17  ? 35  THR B OG1 1 
ATOM 3507 C CG2 . THR B 2 35  ? 7.230   -20.798 -140.214 1.00 69.55  ? 35  THR B CG2 1 
ATOM 3508 N N   . SER B 2 36  ? 2.689   -21.344 -140.728 1.00 73.62  ? 36  SER B N   1 
ATOM 3509 C CA  . SER B 2 36  ? 1.449   -21.261 -141.479 1.00 75.12  ? 36  SER B CA  1 
ATOM 3510 C C   . SER B 2 36  ? 0.349   -22.053 -140.788 1.00 73.81  ? 36  SER B C   1 
ATOM 3511 O O   . SER B 2 36  ? 0.625   -23.044 -140.110 1.00 78.28  ? 36  SER B O   1 
ATOM 3512 C CB  . SER B 2 36  ? 1.644   -21.791 -142.905 1.00 76.93  ? 36  SER B CB  1 
ATOM 3513 O OG  . SER B 2 36  ? 2.267   -23.062 -142.892 1.00 84.88  ? 36  SER B OG  1 
ATOM 3514 N N   . PRO B 2 37  ? -0.904  -21.641 -140.946 1.00 64.31  ? 37  PRO B N   1 
ATOM 3515 C CA  . PRO B 2 37  ? -2.003  -22.397 -140.345 1.00 66.97  ? 37  PRO B CA  1 
ATOM 3516 C C   . PRO B 2 37  ? -2.241  -23.699 -141.087 1.00 70.65  ? 37  PRO B C   1 
ATOM 3517 O O   . PRO B 2 37  ? -1.842  -23.873 -142.239 1.00 77.90  ? 37  PRO B O   1 
ATOM 3518 C CB  . PRO B 2 37  ? -3.207  -21.461 -140.470 1.00 69.57  ? 37  PRO B CB  1 
ATOM 3519 C CG  . PRO B 2 37  ? -2.834  -20.435 -141.457 1.00 67.46  ? 37  PRO B CG  1 
ATOM 3520 C CD  . PRO B 2 37  ? -1.366  -20.480 -141.720 1.00 69.56  ? 37  PRO B CD  1 
ATOM 3521 N N   . LEU B 2 38  ? -2.908  -24.627 -140.398 1.00 65.24  ? 38  LEU B N   1 
ATOM 3522 C CA  . LEU B 2 38  ? -3.162  -25.942 -140.977 1.00 61.70  ? 38  LEU B CA  1 
ATOM 3523 C C   . LEU B 2 38  ? -4.007  -25.834 -142.237 1.00 66.14  ? 38  LEU B C   1 
ATOM 3524 O O   . LEU B 2 38  ? -3.656  -26.386 -143.285 1.00 71.01  ? 38  LEU B O   1 
ATOM 3525 C CB  . LEU B 2 38  ? -3.846  -26.843 -139.954 1.00 54.75  ? 38  LEU B CB  1 
ATOM 3526 C CG  . LEU B 2 38  ? -2.932  -27.571 -138.978 1.00 60.07  ? 38  LEU B CG  1 
ATOM 3527 C CD1 . LEU B 2 38  ? -3.750  -28.392 -138.014 1.00 64.01  ? 38  LEU B CD1 1 
ATOM 3528 C CD2 . LEU B 2 38  ? -1.964  -28.447 -139.733 1.00 62.80  ? 38  LEU B CD2 1 
ATOM 3529 N N   . VAL B 2 39  ? -5.133  -25.129 -142.154 1.00 69.45  ? 39  VAL B N   1 
ATOM 3530 C CA  . VAL B 2 39  ? -6.020  -24.932 -143.289 1.00 65.98  ? 39  VAL B CA  1 
ATOM 3531 C C   . VAL B 2 39  ? -6.380  -23.458 -143.362 1.00 74.17  ? 39  VAL B C   1 
ATOM 3532 O O   . VAL B 2 39  ? -6.288  -22.722 -142.379 1.00 83.24  ? 39  VAL B O   1 
ATOM 3533 C CB  . VAL B 2 39  ? -7.300  -25.785 -143.196 1.00 60.91  ? 39  VAL B CB  1 
ATOM 3534 C CG1 . VAL B 2 39  ? -6.955  -27.236 -142.990 1.00 68.42  ? 39  VAL B CG1 1 
ATOM 3535 C CG2 . VAL B 2 39  ? -8.175  -25.294 -142.076 1.00 64.66  ? 39  VAL B CG2 1 
ATOM 3536 N N   . THR B 2 40  ? -6.781  -23.028 -144.552 1.00 74.57  ? 40  THR B N   1 
ATOM 3537 C CA  . THR B 2 40  ? -7.289  -21.683 -144.744 1.00 72.35  ? 40  THR B CA  1 
ATOM 3538 C C   . THR B 2 40  ? -8.563  -21.776 -145.570 1.00 71.98  ? 40  THR B C   1 
ATOM 3539 O O   . THR B 2 40  ? -8.496  -22.029 -146.783 1.00 79.34  ? 40  THR B O   1 
ATOM 3540 C CB  . THR B 2 40  ? -6.269  -20.788 -145.442 1.00 76.38  ? 40  THR B CB  1 
ATOM 3541 O OG1 . THR B 2 40  ? -5.550  -21.556 -146.411 1.00 81.06  ? 40  THR B OG1 1 
ATOM 3542 C CG2 . THR B 2 40  ? -5.295  -20.212 -144.432 1.00 74.13  ? 40  THR B CG2 1 
ATOM 3543 N N   . PRO B 2 41  ? -9.731  -21.570 -144.970 1.00 62.60  ? 41  PRO B N   1 
ATOM 3544 C CA  . PRO B 2 41  ? -10.980 -21.761 -145.705 1.00 63.22  ? 41  PRO B CA  1 
ATOM 3545 C C   . PRO B 2 41  ? -11.267 -20.603 -146.642 1.00 68.94  ? 41  PRO B C   1 
ATOM 3546 O O   . PRO B 2 41  ? -11.085 -19.432 -146.306 1.00 78.25  ? 41  PRO B O   1 
ATOM 3547 C CB  . PRO B 2 41  ? -12.025 -21.836 -144.587 1.00 70.51  ? 41  PRO B CB  1 
ATOM 3548 C CG  . PRO B 2 41  ? -11.436 -21.078 -143.453 1.00 67.03  ? 41  PRO B CG  1 
ATOM 3549 C CD  . PRO B 2 41  ? -9.953  -20.961 -143.651 1.00 65.44  ? 41  PRO B CD  1 
ATOM 3550 N N   . VAL B 2 42  ? -11.721 -20.946 -147.839 1.00 65.58  ? 42  VAL B N   1 
ATOM 3551 C CA  . VAL B 2 42  ? -12.116 -19.968 -148.842 1.00 62.15  ? 42  VAL B CA  1 
ATOM 3552 C C   . VAL B 2 42  ? -13.634 -19.957 -148.885 1.00 62.24  ? 42  VAL B C   1 
ATOM 3553 O O   . VAL B 2 42  ? -14.259 -20.951 -149.260 1.00 72.74  ? 42  VAL B O   1 
ATOM 3554 C CB  . VAL B 2 42  ? -11.525 -20.299 -150.216 1.00 63.05  ? 42  VAL B CB  1 
ATOM 3555 C CG1 . VAL B 2 42  ? -11.583 -19.085 -151.111 1.00 65.78  ? 42  VAL B CG1 1 
ATOM 3556 C CG2 . VAL B 2 42  ? -10.103 -20.787 -150.068 1.00 65.93  ? 42  VAL B CG2 1 
ATOM 3557 N N   . VAL B 2 43  ? -14.232 -18.835 -148.507 1.00 56.26  ? 43  VAL B N   1 
ATOM 3558 C CA  . VAL B 2 43  ? -15.680 -18.710 -148.437 1.00 63.81  ? 43  VAL B CA  1 
ATOM 3559 C C   . VAL B 2 43  ? -16.150 -18.014 -149.704 1.00 67.04  ? 43  VAL B C   1 
ATOM 3560 O O   . VAL B 2 43  ? -15.769 -16.869 -149.973 1.00 72.08  ? 43  VAL B O   1 
ATOM 3561 C CB  . VAL B 2 43  ? -16.114 -17.932 -147.187 1.00 68.95  ? 43  VAL B CB  1 
ATOM 3562 C CG1 . VAL B 2 43  ? -17.489 -17.331 -147.383 1.00 67.42  ? 43  VAL B CG1 1 
ATOM 3563 C CG2 . VAL B 2 43  ? -16.089 -18.828 -145.973 1.00 69.57  ? 43  VAL B CG2 1 
ATOM 3564 N N   . GLY B 2 44  ? -16.970 -18.701 -150.488 1.00 75.34  ? 44  GLY B N   1 
ATOM 3565 C CA  . GLY B 2 44  ? -17.496 -18.115 -151.698 1.00 76.00  ? 44  GLY B CA  1 
ATOM 3566 C C   . GLY B 2 44  ? -18.525 -17.048 -151.401 1.00 76.92  ? 44  GLY B C   1 
ATOM 3567 O O   . GLY B 2 44  ? -19.033 -16.919 -150.289 1.00 81.13  ? 44  GLY B O   1 
ATOM 3568 N N   . ALA B 2 45  ? -18.839 -16.258 -152.428 1.00 69.68  ? 45  ALA B N   1 
ATOM 3569 C CA  . ALA B 2 45  ? -19.811 -15.188 -152.253 1.00 65.58  ? 45  ALA B CA  1 
ATOM 3570 C C   . ALA B 2 45  ? -21.191 -15.721 -151.907 1.00 68.74  ? 45  ALA B C   1 
ATOM 3571 O O   . ALA B 2 45  ? -21.981 -15.001 -151.291 1.00 70.57  ? 45  ALA B O   1 
ATOM 3572 C CB  . ALA B 2 45  ? -19.885 -14.328 -153.511 1.00 65.03  ? 45  ALA B CB  1 
ATOM 3573 N N   . GLY B 2 46  ? -21.494 -16.959 -152.279 1.00 77.60  ? 46  GLY B N   1 
ATOM 3574 C CA  . GLY B 2 46  ? -22.746 -17.592 -151.938 1.00 78.22  ? 46  GLY B CA  1 
ATOM 3575 C C   . GLY B 2 46  ? -22.756 -18.302 -150.605 1.00 82.63  ? 46  GLY B C   1 
ATOM 3576 O O   . GLY B 2 46  ? -23.757 -18.943 -150.267 1.00 84.57  ? 46  GLY B O   1 
ATOM 3577 N N   . GLY B 2 47  ? -21.676 -18.214 -149.833 1.00 85.88  ? 47  GLY B N   1 
ATOM 3578 C CA  . GLY B 2 47  ? -21.614 -18.818 -148.525 1.00 84.18  ? 47  GLY B CA  1 
ATOM 3579 C C   . GLY B 2 47  ? -20.980 -20.189 -148.465 1.00 87.38  ? 47  GLY B C   1 
ATOM 3580 O O   . GLY B 2 47  ? -20.708 -20.674 -147.361 1.00 92.24  ? 47  GLY B O   1 
ATOM 3581 N N   . GLN B 2 48  ? -20.730 -20.831 -149.601 1.00 83.18  ? 48  GLN B N   1 
ATOM 3582 C CA  . GLN B 2 48  ? -20.120 -22.151 -149.576 1.00 79.25  ? 48  GLN B CA  1 
ATOM 3583 C C   . GLN B 2 48  ? -18.669 -22.055 -149.128 1.00 83.27  ? 48  GLN B C   1 
ATOM 3584 O O   . GLN B 2 48  ? -18.000 -21.042 -149.336 1.00 90.49  ? 48  GLN B O   1 
ATOM 3585 C CB  . GLN B 2 48  ? -20.197 -22.811 -150.947 1.00 76.98  ? 48  GLN B CB  1 
ATOM 3586 C CG  . GLN B 2 48  ? -21.603 -23.002 -151.448 1.00 79.20  ? 48  GLN B CG  1 
ATOM 3587 C CD  . GLN B 2 48  ? -21.642 -23.649 -152.810 1.00 90.58  ? 48  GLN B CD  1 
ATOM 3588 O OE1 . GLN B 2 48  ? -20.609 -24.045 -153.353 1.00 90.22  ? 48  GLN B OE1 1 
ATOM 3589 N NE2 . GLN B 2 48  ? -22.838 -23.771 -153.371 1.00 91.36  ? 48  GLN B NE2 1 
ATOM 3590 N N   . VAL B 2 49  ? -18.186 -23.121 -148.499 1.00 68.69  ? 49  VAL B N   1 
ATOM 3591 C CA  . VAL B 2 49  ? -16.864 -23.145 -147.889 1.00 63.12  ? 49  VAL B CA  1 
ATOM 3592 C C   . VAL B 2 49  ? -16.063 -24.280 -148.504 1.00 70.97  ? 49  VAL B C   1 
ATOM 3593 O O   . VAL B 2 49  ? -16.531 -25.422 -148.542 1.00 80.90  ? 49  VAL B O   1 
ATOM 3594 C CB  . VAL B 2 49  ? -16.950 -23.317 -146.365 1.00 67.50  ? 49  VAL B CB  1 
ATOM 3595 C CG1 . VAL B 2 49  ? -15.589 -23.615 -145.792 1.00 68.27  ? 49  VAL B CG1 1 
ATOM 3596 C CG2 . VAL B 2 49  ? -17.532 -22.083 -145.734 1.00 72.93  ? 49  VAL B CG2 1 
ATOM 3597 N N   . ALA B 2 50  ? -14.863 -23.969 -148.978 1.00 63.12  ? 50  ALA B N   1 
ATOM 3598 C CA  . ALA B 2 50  ? -13.925 -24.970 -149.464 1.00 62.36  ? 50  ALA B CA  1 
ATOM 3599 C C   . ALA B 2 50  ? -12.604 -24.796 -148.736 1.00 69.46  ? 50  ALA B C   1 
ATOM 3600 O O   . ALA B 2 50  ? -11.975 -23.740 -148.835 1.00 76.57  ? 50  ALA B O   1 
ATOM 3601 C CB  . ALA B 2 50  ? -13.717 -24.850 -150.972 1.00 59.79  ? 50  ALA B CB  1 
ATOM 3602 N N   . LEU B 2 51  ? -12.183 -25.826 -148.016 1.00 66.84  ? 51  LEU B N   1 
ATOM 3603 C CA  . LEU B 2 51  ? -10.941 -25.766 -147.265 1.00 62.11  ? 51  LEU B CA  1 
ATOM 3604 C C   . LEU B 2 51  ? -9.749  -25.870 -148.202 1.00 68.92  ? 51  LEU B C   1 
ATOM 3605 O O   . LEU B 2 51  ? -9.820  -26.491 -149.264 1.00 73.54  ? 51  LEU B O   1 
ATOM 3606 C CB  . LEU B 2 51  ? -10.868 -26.886 -146.234 1.00 57.66  ? 51  LEU B CB  1 
ATOM 3607 C CG  . LEU B 2 51  ? -12.022 -27.005 -145.252 1.00 66.22  ? 51  LEU B CG  1 
ATOM 3608 C CD1 . LEU B 2 51  ? -11.905 -28.305 -144.489 1.00 69.87  ? 51  LEU B CD1 1 
ATOM 3609 C CD2 . LEU B 2 51  ? -12.019 -25.829 -144.307 1.00 67.31  ? 51  LEU B CD2 1 
ATOM 3610 N N   . THR B 2 52  ? -8.611  -25.331 -147.764 1.00 70.58  ? 52  THR B N   1 
ATOM 3611 C CA  . THR B 2 52  ? -7.354  -25.465 -148.516 1.00 63.09  ? 52  THR B CA  1 
ATOM 3612 C C   . THR B 2 52  ? -6.352  -25.998 -147.540 1.00 68.09  ? 52  THR B C   1 
ATOM 3613 O O   . THR B 2 52  ? -5.913  -25.213 -146.699 1.00 76.29  ? 52  THR B O   1 
ATOM 3614 C CB  . THR B 2 52  ? -6.908  -24.108 -149.029 1.00 67.21  ? 52  THR B CB  1 
ATOM 3615 O OG1 . THR B 2 52  ? -7.903  -23.764 -149.987 1.00 71.45  ? 52  THR B OG1 1 
ATOM 3616 C CG2 . THR B 2 52  ? -5.542  -24.151 -149.687 1.00 67.47  ? 52  THR B CG2 1 
ATOM 3617 N N   . ARG B 2 53  ? -6.024  -27.282 -147.598 1.00 69.48  ? 53  ARG B N   1 
ATOM 3618 C CA  . ARG B 2 53  ? -5.140  -27.867 -146.566 1.00 68.19  ? 53  ARG B CA  1 
ATOM 3619 C C   . ARG B 2 53  ? -3.702  -27.470 -146.877 1.00 71.92  ? 53  ARG B C   1 
ATOM 3620 O O   . ARG B 2 53  ? -3.147  -28.017 -147.831 1.00 76.71  ? 53  ARG B O   1 
ATOM 3621 C CB  . ARG B 2 53  ? -5.364  -29.376 -146.536 1.00 70.52  ? 53  ARG B CB  1 
ATOM 3622 C CG  . ARG B 2 53  ? -6.838  -29.747 -146.524 1.00 79.48  ? 53  ARG B CG  1 
ATOM 3623 C CD  . ARG B 2 53  ? -7.212  -30.550 -145.295 1.00 76.22  ? 53  ARG B CD  1 
ATOM 3624 N NE  . ARG B 2 53  ? -6.038  -31.180 -144.684 1.00 67.48  ? 53  ARG B NE  1 
ATOM 3625 C CZ  . ARG B 2 53  ? -5.738  -31.101 -143.398 1.00 73.62  ? 53  ARG B CZ  1 
ATOM 3626 N NH1 . ARG B 2 53  ? -4.516  -31.385 -142.988 1.00 63.08  ? 53  ARG B NH1 1 
ATOM 3627 N NH2 . ARG B 2 53  ? -6.660  -30.734 -142.529 1.00 76.32  ? 53  ARG B NH2 1 
ATOM 3628 N N   . ASN B 2 54  ? -3.116  -26.587 -146.073 1.00 74.66  ? 54  ASN B N   1 
ATOM 3629 C CA  . ASN B 2 54  ? -1.764  -26.059 -146.385 1.00 75.72  ? 54  ASN B CA  1 
ATOM 3630 C C   . ASN B 2 54  ? -0.754  -27.196 -146.342 1.00 78.84  ? 54  ASN B C   1 
ATOM 3631 O O   . ASN B 2 54  ? -0.956  -28.121 -145.547 1.00 83.05  ? 54  ASN B O   1 
ATOM 3632 C CB  . ASN B 2 54  ? -1.383  -24.899 -145.479 1.00 75.79  ? 54  ASN B CB  1 
ATOM 3633 C CG  . ASN B 2 54  ? -2.264  -23.693 -145.687 1.00 73.21  ? 54  ASN B CG  1 
ATOM 3634 O OD1 . ASN B 2 54  ? -3.336  -23.596 -145.086 1.00 73.51  ? 54  ASN B OD1 1 
ATOM 3635 N ND2 . ASN B 2 54  ? -1.829  -22.764 -146.523 1.00 74.86  ? 54  ASN B ND2 1 
ATOM 3636 N N   . ALA B 2 55  ? 0.290   -27.115 -147.160 1.00 85.15  ? 55  ALA B N   1 
ATOM 3637 C CA  . ALA B 2 55  ? 1.324   -28.131 -147.256 1.00 88.12  ? 55  ALA B CA  1 
ATOM 3638 C C   . ALA B 2 55  ? 2.628   -27.721 -146.593 1.00 84.89  ? 55  ALA B C   1 
ATOM 3639 O O   . ALA B 2 55  ? 3.614   -28.453 -146.697 1.00 88.59  ? 55  ALA B O   1 
ATOM 3640 C CB  . ALA B 2 55  ? 1.583   -28.476 -148.722 1.00 88.96  ? 55  ALA B CB  1 
ATOM 3641 N N   . ASP B 2 56  ? 2.663   -26.577 -145.926 1.00 81.45  ? 56  ASP B N   1 
ATOM 3642 C CA  . ASP B 2 56  ? 3.885   -26.069 -145.320 1.00 80.79  ? 56  ASP B CA  1 
ATOM 3643 C C   . ASP B 2 56  ? 3.865   -26.370 -143.826 1.00 81.03  ? 56  ASP B C   1 
ATOM 3644 O O   . ASP B 2 56  ? 3.017   -25.850 -143.094 1.00 83.29  ? 56  ASP B O   1 
ATOM 3645 C CB  . ASP B 2 56  ? 4.016   -24.571 -145.595 1.00 83.95  ? 56  ASP B CB  1 
ATOM 3646 C CG  . ASP B 2 56  ? 5.023   -23.890 -144.700 1.00 88.60  ? 56  ASP B CG  1 
ATOM 3647 O OD1 . ASP B 2 56  ? 4.733   -23.691 -143.502 1.00 90.44  ? 56  ASP B OD1 1 
ATOM 3648 O OD2 . ASP B 2 56  ? 6.113   -23.544 -145.200 1.00 91.18  ? 56  ASP B OD2 1 
ATOM 3649 N N   . LYS B 2 57  ? 4.801   -27.204 -143.377 1.00 75.11  ? 57  LYS B N   1 
ATOM 3650 C CA  . LYS B 2 57  ? 4.883   -27.620 -141.984 1.00 70.95  ? 57  LYS B CA  1 
ATOM 3651 C C   . LYS B 2 57  ? 6.045   -26.958 -141.255 1.00 77.33  ? 57  LYS B C   1 
ATOM 3652 O O   . LYS B 2 57  ? 6.395   -27.369 -140.147 1.00 83.61  ? 57  LYS B O   1 
ATOM 3653 C CB  . LYS B 2 57  ? 5.009   -29.139 -141.906 1.00 72.40  ? 57  LYS B CB  1 
ATOM 3654 C CG  . LYS B 2 57  ? 4.040   -29.880 -142.806 1.00 79.98  ? 57  LYS B CG  1 
ATOM 3655 C CD  . LYS B 2 57  ? 2.916   -30.528 -142.024 1.00 80.79  ? 57  LYS B CD  1 
ATOM 3656 C CE  . LYS B 2 57  ? 1.805   -31.002 -142.945 1.00 80.66  ? 57  LYS B CE  1 
ATOM 3657 N NZ  . LYS B 2 57  ? 0.618   -30.106 -142.890 1.00 76.59  ? 57  LYS B NZ  1 
ATOM 3658 N N   . THR B 2 58  ? 6.649   -25.941 -141.857 1.00 74.15  ? 58  THR B N   1 
ATOM 3659 C CA  . THR B 2 58  ? 7.837   -25.310 -141.305 1.00 68.29  ? 58  THR B CA  1 
ATOM 3660 C C   . THR B 2 58  ? 7.506   -24.549 -140.030 1.00 75.01  ? 58  THR B C   1 
ATOM 3661 O O   . THR B 2 58  ? 6.470   -23.887 -139.937 1.00 80.02  ? 58  THR B O   1 
ATOM 3662 C CB  . THR B 2 58  ? 8.444   -24.367 -142.342 1.00 70.97  ? 58  THR B CB  1 
ATOM 3663 O OG1 . THR B 2 58  ? 8.991   -25.135 -143.417 1.00 76.80  ? 58  THR B OG1 1 
ATOM 3664 C CG2 . THR B 2 58  ? 9.540   -23.525 -141.736 1.00 80.34  ? 58  THR B CG2 1 
ATOM 3665 N N   . GLY B 2 59  ? 8.391   -24.653 -139.038 1.00 75.29  ? 59  GLY B N   1 
ATOM 3666 C CA  . GLY B 2 59  ? 8.239   -23.915 -137.807 1.00 75.61  ? 59  GLY B CA  1 
ATOM 3667 C C   . GLY B 2 59  ? 9.537   -23.236 -137.417 1.00 76.59  ? 59  GLY B C   1 
ATOM 3668 O O   . GLY B 2 59  ? 10.608  -23.549 -137.932 1.00 80.82  ? 59  GLY B O   1 
ATOM 3669 N N   . THR B 2 60  ? 9.419   -22.283 -136.497 1.00 71.98  ? 60  THR B N   1 
ATOM 3670 C CA  . THR B 2 60  ? 10.563  -21.552 -135.968 1.00 75.24  ? 60  THR B CA  1 
ATOM 3671 C C   . THR B 2 60  ? 10.654  -21.777 -134.469 1.00 75.89  ? 60  THR B C   1 
ATOM 3672 O O   . THR B 2 60  ? 9.655   -21.650 -133.757 1.00 81.45  ? 60  THR B O   1 
ATOM 3673 C CB  . THR B 2 60  ? 10.453  -20.055 -136.250 1.00 76.48  ? 60  THR B CB  1 
ATOM 3674 O OG1 . THR B 2 60  ? 9.698   -19.432 -135.209 1.00 77.66  ? 60  THR B OG1 1 
ATOM 3675 C CG2 . THR B 2 60  ? 9.769   -19.811 -137.578 1.00 74.94  ? 60  THR B CG2 1 
ATOM 3676 N N   . ILE B 2 61  ? 11.854  -22.091 -133.992 1.00 68.79  ? 61  ILE B N   1 
ATOM 3677 C CA  . ILE B 2 61  ? 12.105  -22.375 -132.585 1.00 70.38  ? 61  ILE B CA  1 
ATOM 3678 C C   . ILE B 2 61  ? 12.924  -21.233 -132.007 1.00 73.00  ? 61  ILE B C   1 
ATOM 3679 O O   . ILE B 2 61  ? 14.033  -20.956 -132.480 1.00 77.13  ? 61  ILE B O   1 
ATOM 3680 C CB  . ILE B 2 61  ? 12.833  -23.710 -132.404 1.00 63.27  ? 61  ILE B CB  1 
ATOM 3681 C CG1 . ILE B 2 61  ? 11.981  -24.849 -132.951 1.00 59.18  ? 61  ILE B CG1 1 
ATOM 3682 C CG2 . ILE B 2 61  ? 13.180  -23.924 -130.951 1.00 61.76  ? 61  ILE B CG2 1 
ATOM 3683 C CD1 . ILE B 2 61  ? 12.579  -26.196 -132.716 1.00 63.13  ? 61  ILE B CD1 1 
ATOM 3684 N N   . GLU B 2 62  ? 12.393  -20.579 -130.982 1.00 69.49  ? 62  GLU B N   1 
ATOM 3685 C CA  . GLU B 2 62  ? 13.069  -19.478 -130.313 1.00 64.07  ? 62  GLU B CA  1 
ATOM 3686 C C   . GLU B 2 62  ? 13.403  -19.911 -128.896 1.00 70.01  ? 62  GLU B C   1 
ATOM 3687 O O   . GLU B 2 62  ? 12.509  -20.308 -128.144 1.00 76.96  ? 62  GLU B O   1 
ATOM 3688 C CB  . GLU B 2 62  ? 12.194  -18.230 -130.297 1.00 70.97  ? 62  GLU B CB  1 
ATOM 3689 C CG  . GLU B 2 62  ? 11.752  -17.771 -131.669 1.00 80.39  ? 62  GLU B CG  1 
ATOM 3690 C CD  . GLU B 2 62  ? 10.958  -16.484 -131.626 1.00 83.97  ? 62  GLU B CD  1 
ATOM 3691 O OE1 . GLU B 2 62  ? 9.739   -16.528 -131.888 1.00 84.35  ? 62  GLU B OE1 1 
ATOM 3692 O OE2 . GLU B 2 62  ? 11.554  -15.428 -131.335 1.00 83.23  ? 62  GLU B OE2 1 
ATOM 3693 N N   . ILE B 2 63  ? 14.677  -19.830 -128.533 1.00 67.21  ? 63  ILE B N   1 
ATOM 3694 C CA  . ILE B 2 63  ? 15.149  -20.264 -127.226 1.00 61.49  ? 63  ILE B CA  1 
ATOM 3695 C C   . ILE B 2 63  ? 15.976  -19.147 -126.608 1.00 60.32  ? 63  ILE B C   1 
ATOM 3696 O O   . ILE B 2 63  ? 16.816  -18.540 -127.280 1.00 64.42  ? 63  ILE B O   1 
ATOM 3697 C CB  . ILE B 2 63  ? 15.963  -21.569 -127.326 1.00 53.67  ? 63  ILE B CB  1 
ATOM 3698 C CG1 . ILE B 2 63  ? 16.599  -21.906 -125.986 1.00 60.08  ? 63  ILE B CG1 1 
ATOM 3699 C CG2 . ILE B 2 63  ? 17.019  -21.462 -128.394 1.00 54.94  ? 63  ILE B CG2 1 
ATOM 3700 C CD1 . ILE B 2 63  ? 16.887  -23.365 -125.820 1.00 62.25  ? 63  ILE B CD1 1 
ATOM 3701 N N   . GLU B 2 64  ? 15.723  -18.862 -125.336 1.00 70.91  ? 64  GLU B N   1 
ATOM 3702 C CA  . GLU B 2 64  ? 16.381  -17.782 -124.616 1.00 66.74  ? 64  GLU B CA  1 
ATOM 3703 C C   . GLU B 2 64  ? 17.279  -18.357 -123.534 1.00 69.83  ? 64  GLU B C   1 
ATOM 3704 O O   . GLU B 2 64  ? 16.832  -19.171 -122.721 1.00 77.69  ? 64  GLU B O   1 
ATOM 3705 C CB  . GLU B 2 64  ? 15.355  -16.844 -123.986 1.00 67.10  ? 64  GLU B CB  1 
ATOM 3706 C CG  . GLU B 2 64  ? 14.911  -15.720 -124.884 1.00 76.15  ? 64  GLU B CG  1 
ATOM 3707 C CD  . GLU B 2 64  ? 14.001  -14.747 -124.174 1.00 81.87  ? 64  GLU B CD  1 
ATOM 3708 O OE1 . GLU B 2 64  ? 14.262  -14.443 -122.993 1.00 85.11  ? 64  GLU B OE1 1 
ATOM 3709 O OE2 . GLU B 2 64  ? 13.019  -14.293 -124.794 1.00 82.56  ? 64  GLU B OE2 1 
ATOM 3710 N N   . LEU B 2 65  ? 18.533  -17.924 -123.511 1.00 63.70  ? 65  LEU B N   1 
ATOM 3711 C CA  . LEU B 2 65  ? 19.490  -18.373 -122.514 1.00 62.52  ? 65  LEU B CA  1 
ATOM 3712 C C   . LEU B 2 65  ? 19.948  -17.193 -121.672 1.00 67.08  ? 65  LEU B C   1 
ATOM 3713 O O   . LEU B 2 65  ? 19.864  -16.038 -122.092 1.00 72.16  ? 65  LEU B O   1 
ATOM 3714 C CB  . LEU B 2 65  ? 20.699  -19.045 -123.165 1.00 63.01  ? 65  LEU B CB  1 
ATOM 3715 C CG  . LEU B 2 65  ? 20.392  -19.987 -124.322 1.00 57.67  ? 65  LEU B CG  1 
ATOM 3716 C CD1 . LEU B 2 65  ? 21.667  -20.583 -124.859 1.00 64.23  ? 65  LEU B CD1 1 
ATOM 3717 C CD2 . LEU B 2 65  ? 19.455  -21.071 -123.870 1.00 64.92  ? 65  LEU B CD2 1 
ATOM 3718 N N   . MET B 2 66  ? 20.439  -17.496 -120.473 1.00 70.11  ? 66  MET B N   1 
ATOM 3719 C CA  . MET B 2 66  ? 20.955  -16.451 -119.608 1.00 71.02  ? 66  MET B CA  1 
ATOM 3720 C C   . MET B 2 66  ? 22.105  -15.728 -120.292 1.00 75.87  ? 66  MET B C   1 
ATOM 3721 O O   . MET B 2 66  ? 22.758  -16.256 -121.193 1.00 82.84  ? 66  MET B O   1 
ATOM 3722 C CB  . MET B 2 66  ? 21.429  -17.026 -118.276 1.00 70.48  ? 66  MET B CB  1 
ATOM 3723 C CG  . MET B 2 66  ? 20.327  -17.324 -117.293 1.00 70.75  ? 66  MET B CG  1 
ATOM 3724 S SD  . MET B 2 66  ? 20.948  -18.146 -115.822 1.00 91.18  ? 66  MET B SD  1 
ATOM 3725 C CE  . MET B 2 66  ? 19.414  -18.609 -115.029 1.00 76.38  ? 66  MET B CE  1 
ATOM 3726 N N   . GLN B 2 67  ? 22.349  -14.498 -119.848 1.00 72.73  ? 67  GLN B N   1 
ATOM 3727 C CA  . GLN B 2 67  ? 23.322  -13.653 -120.528 1.00 75.74  ? 67  GLN B CA  1 
ATOM 3728 C C   . GLN B 2 67  ? 24.713  -14.264 -120.489 1.00 78.44  ? 67  GLN B C   1 
ATOM 3729 O O   . GLN B 2 67  ? 25.438  -14.232 -121.488 1.00 84.69  ? 67  GLN B O   1 
ATOM 3730 C CB  . GLN B 2 67  ? 23.332  -12.264 -119.900 1.00 77.66  ? 67  GLN B CB  1 
ATOM 3731 C CG  . GLN B 2 67  ? 24.094  -11.246 -120.705 1.00 78.17  ? 67  GLN B CG  1 
ATOM 3732 C CD  . GLN B 2 67  ? 24.597  -10.110 -119.856 1.00 80.15  ? 67  GLN B CD  1 
ATOM 3733 O OE1 . GLN B 2 67  ? 23.831  -9.472  -119.141 1.00 81.31  ? 67  GLN B OE1 1 
ATOM 3734 N NE2 . GLN B 2 67  ? 25.896  -9.857  -119.919 1.00 76.56  ? 67  GLN B NE2 1 
ATOM 3735 N N   . THR B 2 68  ? 25.101  -14.838 -119.354 1.00 75.60  ? 68  THR B N   1 
ATOM 3736 C CA  . THR B 2 68  ? 26.450  -15.351 -119.166 1.00 73.67  ? 68  THR B CA  1 
ATOM 3737 C C   . THR B 2 68  ? 26.527  -16.864 -119.300 1.00 80.78  ? 68  THR B C   1 
ATOM 3738 O O   . THR B 2 68  ? 27.518  -17.467 -118.879 1.00 86.85  ? 68  THR B O   1 
ATOM 3739 C CB  . THR B 2 68  ? 26.989  -14.923 -117.806 1.00 76.80  ? 68  THR B CB  1 
ATOM 3740 O OG1 . THR B 2 68  ? 25.923  -14.931 -116.852 1.00 84.53  ? 68  THR B OG1 1 
ATOM 3741 C CG2 . THR B 2 68  ? 27.564  -13.534 -117.890 1.00 79.72  ? 68  THR B CG2 1 
ATOM 3742 N N   . SER B 2 69  ? 25.510  -17.490 -119.880 1.00 78.16  ? 69  SER B N   1 
ATOM 3743 C CA  . SER B 2 69  ? 25.494  -18.940 -119.993 1.00 74.92  ? 69  SER B CA  1 
ATOM 3744 C C   . SER B 2 69  ? 26.613  -19.429 -120.902 1.00 84.94  ? 69  SER B C   1 
ATOM 3745 O O   . SER B 2 69  ? 27.003  -18.762 -121.861 1.00 83.90  ? 69  SER B O   1 
ATOM 3746 C CB  . SER B 2 69  ? 24.153  -19.416 -120.533 1.00 72.14  ? 69  SER B CB  1 
ATOM 3747 O OG  . SER B 2 69  ? 24.251  -20.757 -120.960 1.00 79.06  ? 69  SER B OG  1 
ATOM 3748 N N   . LEU B 2 70  ? 27.067  -20.654 -120.678 1.00 90.30  ? 70  LEU B N   1 
ATOM 3749 C CA  . LEU B 2 70  ? 28.188  -21.172 -121.495 1.00 87.00  ? 70  LEU B CA  1 
ATOM 3750 C C   . LEU B 2 70  ? 27.638  -21.526 -122.878 1.00 91.78  ? 70  LEU B C   1 
ATOM 3751 O O   . LEU B 2 70  ? 28.321  -21.245 -123.870 1.00 95.27  ? 70  LEU B O   1 
ATOM 3752 C CB  . LEU B 2 70  ? 28.858  -22.368 -120.831 1.00 81.63  ? 70  LEU B CB  1 
ATOM 3753 C CG  . LEU B 2 70  ? 30.358  -22.220 -120.574 1.00 85.57  ? 70  LEU B CG  1 
ATOM 3754 C CD1 . LEU B 2 70  ? 31.099  -22.174 -121.896 1.00 85.46  ? 70  LEU B CD1 1 
ATOM 3755 C CD2 . LEU B 2 70  ? 30.614  -20.958 -119.777 1.00 85.16  ? 70  LEU B CD2 1 
ATOM 3756 N N   . SER B 2 71  ? 26.438  -22.094 -122.941 1.00 84.88  ? 71  SER B N   1 
ATOM 3757 C CA  . SER B 2 71  ? 25.890  -22.516 -124.251 1.00 79.87  ? 71  SER B CA  1 
ATOM 3758 C C   . SER B 2 71  ? 25.996  -21.355 -125.243 1.00 79.57  ? 71  SER B C   1 
ATOM 3759 O O   . SER B 2 71  ? 26.333  -21.595 -126.409 1.00 79.69  ? 71  SER B O   1 
ATOM 3760 C CB  . SER B 2 71  ? 24.490  -22.966 -124.113 1.00 78.85  ? 71  SER B CB  1 
ATOM 3761 O OG  . SER B 2 71  ? 24.376  -23.932 -123.080 1.00 78.82  ? 71  SER B OG  1 
ATOM 3762 N N   . ASN B 2 72  ? 25.742  -20.136 -124.781 1.00 76.04  ? 72  ASN B N   1 
ATOM 3763 C CA  . ASN B 2 72  ? 25.800  -18.955 -125.674 1.00 73.01  ? 72  ASN B CA  1 
ATOM 3764 C C   . ASN B 2 72  ? 27.140  -18.955 -126.401 1.00 72.82  ? 72  ASN B C   1 
ATOM 3765 O O   . ASN B 2 72  ? 27.193  -18.448 -127.525 1.00 63.03  ? 72  ASN B O   1 
ATOM 3766 C CB  . ASN B 2 72  ? 25.614  -17.657 -124.911 1.00 71.19  ? 72  ASN B CB  1 
ATOM 3767 C CG  . ASN B 2 72  ? 24.226  -17.515 -124.353 1.00 70.32  ? 72  ASN B CG  1 
ATOM 3768 O OD1 . ASN B 2 72  ? 23.994  -17.862 -123.194 1.00 74.66  ? 72  ASN B OD1 1 
ATOM 3769 N ND2 . ASN B 2 72  ? 23.300  -17.014 -125.152 1.00 72.39  ? 72  ASN B ND2 1 
ATOM 3770 N N   . GLN B 2 73  ? 28.186  -19.482 -125.777 1.00 76.77  ? 73  GLN B N   1 
ATOM 3771 C CA  . GLN B 2 73  ? 29.527  -19.422 -126.404 1.00 82.05  ? 73  GLN B CA  1 
ATOM 3772 C C   . GLN B 2 73  ? 29.819  -20.771 -127.064 1.00 84.63  ? 73  GLN B C   1 
ATOM 3773 O O   . GLN B 2 73  ? 30.905  -20.905 -127.645 1.00 90.93  ? 73  GLN B O   1 
ATOM 3774 C CB  . GLN B 2 73  ? 30.599  -19.054 -125.383 1.00 81.32  ? 73  GLN B CB  1 
ATOM 3775 C CG  . GLN B 2 73  ? 31.397  -17.806 -125.743 1.00 86.73  ? 73  GLN B CG  1 
ATOM 3776 C CD  . GLN B 2 73  ? 32.666  -18.090 -126.520 1.00 92.93  ? 73  GLN B CD  1 
ATOM 3777 O OE1 . GLN B 2 73  ? 32.713  -17.977 -127.751 1.00 93.81  ? 73  GLN B OE1 1 
ATOM 3778 N NE2 . GLN B 2 73  ? 33.723  -18.446 -125.805 1.00 90.83  ? 73  GLN B NE2 1 
ATOM 3779 N N   . MET B 2 74  ? 28.891  -21.726 -126.984 1.00 30.00  ? 74  MET B N   1 
ATOM 3780 C CA  . MET B 2 74  ? 29.104  -23.008 -127.690 1.00 30.00  ? 74  MET B CA  1 
ATOM 3781 C C   . MET B 2 74  ? 28.302  -22.983 -128.981 1.00 30.00  ? 74  MET B C   1 
ATOM 3782 O O   . MET B 2 74  ? 28.689  -23.660 -129.937 1.00 30.00  ? 74  MET B O   1 
ATOM 3783 C CB  . MET B 2 74  ? 28.713  -24.180 -126.835 1.00 30.00  ? 74  MET B CB  1 
ATOM 3784 N N   . LEU B 2 75  ? 27.218  -22.218 -129.000 1.00 77.78  ? 75  LEU B N   1 
ATOM 3785 C CA  . LEU B 2 75  ? 26.465  -22.053 -130.263 1.00 75.90  ? 75  LEU B CA  1 
ATOM 3786 C C   . LEU B 2 75  ? 27.214  -21.039 -131.134 1.00 78.40  ? 75  LEU B C   1 
ATOM 3787 O O   . LEU B 2 75  ? 27.253  -21.233 -132.354 1.00 78.20  ? 75  LEU B O   1 
ATOM 3788 C CB  . LEU B 2 75  ? 25.033  -21.626 -129.969 1.00 67.75  ? 75  LEU B CB  1 
ATOM 3789 C CG  . LEU B 2 75  ? 24.131  -22.688 -129.341 1.00 66.24  ? 75  LEU B CG  1 
ATOM 3790 C CD1 . LEU B 2 75  ? 23.113  -22.009 -128.453 1.00 68.43  ? 75  LEU B CD1 1 
ATOM 3791 C CD2 . LEU B 2 75  ? 23.436  -23.465 -130.435 1.00 72.41  ? 75  LEU B CD2 1 
ATOM 3792 N N   . SER B 2 76  ? 27.823  -20.021 -130.532 1.00 78.14  ? 76  SER B N   1 
ATOM 3793 C CA  . SER B 2 76  ? 28.591  -19.089 -131.346 1.00 72.25  ? 76  SER B CA  1 
ATOM 3794 C C   . SER B 2 76  ? 29.717  -19.800 -132.081 1.00 73.82  ? 76  SER B C   1 
ATOM 3795 O O   . SER B 2 76  ? 29.942  -19.556 -133.272 1.00 82.09  ? 76  SER B O   1 
ATOM 3796 C CB  . SER B 2 76  ? 29.153  -17.971 -130.474 1.00 78.50  ? 76  SER B CB  1 
ATOM 3797 O OG  . SER B 2 76  ? 28.127  -17.096 -130.051 1.00 78.46  ? 76  SER B OG  1 
ATOM 3798 N N   . ALA B 2 77  ? 30.436  -20.684 -131.388 1.00 63.15  ? 77  ALA B N   1 
ATOM 3799 C CA  . ALA B 2 77  ? 31.509  -21.429 -132.037 1.00 66.56  ? 77  ALA B CA  1 
ATOM 3800 C C   . ALA B 2 77  ? 30.961  -22.342 -133.122 1.00 73.08  ? 77  ALA B C   1 
ATOM 3801 O O   . ALA B 2 77  ? 31.562  -22.479 -134.193 1.00 73.64  ? 77  ALA B O   1 
ATOM 3802 C CB  . ALA B 2 77  ? 32.288  -22.234 -131.003 1.00 66.72  ? 77  ALA B CB  1 
ATOM 3803 N N   . ILE B 2 78  ? 29.815  -22.974 -132.861 1.00 73.10  ? 78  ILE B N   1 
ATOM 3804 C CA  . ILE B 2 78  ? 29.198  -23.835 -133.864 1.00 65.27  ? 78  ILE B CA  1 
ATOM 3805 C C   . ILE B 2 78  ? 28.829  -23.030 -135.099 1.00 69.75  ? 78  ILE B C   1 
ATOM 3806 O O   . ILE B 2 78  ? 29.074  -23.457 -136.231 1.00 77.73  ? 78  ILE B O   1 
ATOM 3807 C CB  . ILE B 2 78  ? 27.972  -24.546 -133.273 1.00 62.94  ? 78  ILE B CB  1 
ATOM 3808 C CG1 . ILE B 2 78  ? 28.412  -25.728 -132.422 1.00 68.85  ? 78  ILE B CG1 1 
ATOM 3809 C CG2 . ILE B 2 78  ? 27.064  -25.027 -134.376 1.00 66.27  ? 78  ILE B CG2 1 
ATOM 3810 C CD1 . ILE B 2 78  ? 27.268  -26.524 -131.869 1.00 68.77  ? 78  ILE B CD1 1 
ATOM 3811 N N   . GLN B 2 79  ? 28.233  -21.855 -134.904 1.00 73.28  ? 79  GLN B N   1 
ATOM 3812 C CA  . GLN B 2 79  ? 27.862  -21.015 -136.035 1.00 71.97  ? 79  GLN B CA  1 
ATOM 3813 C C   . GLN B 2 79  ? 29.091  -20.564 -136.812 1.00 80.26  ? 79  GLN B C   1 
ATOM 3814 O O   . GLN B 2 79  ? 29.082  -20.547 -138.049 1.00 82.69  ? 79  GLN B O   1 
ATOM 3815 C CB  . GLN B 2 79  ? 27.060  -19.811 -135.547 1.00 69.41  ? 79  GLN B CB  1 
ATOM 3816 C CG  . GLN B 2 79  ? 27.138  -18.557 -136.414 1.00 72.56  ? 79  GLN B CG  1 
ATOM 3817 C CD  . GLN B 2 79  ? 26.779  -18.774 -137.873 1.00 80.57  ? 79  GLN B CD  1 
ATOM 3818 O OE1 . GLN B 2 79  ? 26.283  -19.829 -138.262 1.00 82.69  ? 79  GLN B OE1 1 
ATOM 3819 N NE2 . GLN B 2 79  ? 27.047  -17.768 -138.692 1.00 85.42  ? 79  GLN B NE2 1 
ATOM 3820 N N   . ALA B 2 80  ? 30.156  -20.189 -136.105 1.00 85.33  ? 80  ALA B N   1 
ATOM 3821 C CA  . ALA B 2 80  ? 31.374  -19.768 -136.787 1.00 82.98  ? 80  ALA B CA  1 
ATOM 3822 C C   . ALA B 2 80  ? 31.954  -20.903 -137.615 1.00 83.44  ? 80  ALA B C   1 
ATOM 3823 O O   . ALA B 2 80  ? 32.424  -20.687 -138.737 1.00 86.07  ? 80  ALA B O   1 
ATOM 3824 C CB  . ALA B 2 80  ? 32.397  -19.260 -135.776 1.00 81.30  ? 80  ALA B CB  1 
ATOM 3825 N N   . LYS B 2 81  ? 31.934  -22.122 -137.075 1.00 74.57  ? 81  LYS B N   1 
ATOM 3826 C CA  . LYS B 2 81  ? 32.404  -23.271 -137.842 1.00 72.70  ? 81  LYS B CA  1 
ATOM 3827 C C   . LYS B 2 81  ? 31.513  -23.531 -139.049 1.00 74.84  ? 81  LYS B C   1 
ATOM 3828 O O   . LYS B 2 81  ? 32.008  -23.840 -140.137 1.00 85.16  ? 81  LYS B O   1 
ATOM 3829 C CB  . LYS B 2 81  ? 32.472  -24.503 -136.947 1.00 75.04  ? 81  LYS B CB  1 
ATOM 3830 C CG  . LYS B 2 81  ? 32.418  -25.815 -137.696 1.00 77.02  ? 81  LYS B CG  1 
ATOM 3831 C CD  . LYS B 2 81  ? 32.677  -26.987 -136.765 1.00 82.52  ? 81  LYS B CD  1 
ATOM 3832 C CE  . LYS B 2 81  ? 31.389  -27.500 -136.143 1.00 83.62  ? 81  LYS B CE  1 
ATOM 3833 N NZ  . LYS B 2 81  ? 30.675  -28.463 -137.025 1.00 80.94  ? 81  LYS B NZ  1 
ATOM 3834 N N   . GLN B 2 82  ? 30.196  -23.405 -138.879 1.00 74.29  ? 82  GLN B N   1 
ATOM 3835 C CA  . GLN B 2 82  ? 29.282  -23.698 -139.975 1.00 74.73  ? 82  GLN B CA  1 
ATOM 3836 C C   . GLN B 2 82  ? 29.392  -22.677 -141.093 1.00 78.84  ? 82  GLN B C   1 
ATOM 3837 O O   . GLN B 2 82  ? 29.148  -23.009 -142.256 1.00 85.31  ? 82  GLN B O   1 
ATOM 3838 C CB  . GLN B 2 82  ? 27.844  -23.752 -139.475 1.00 67.94  ? 82  GLN B CB  1 
ATOM 3839 C CG  . GLN B 2 82  ? 27.534  -24.958 -138.635 1.00 70.86  ? 82  GLN B CG  1 
ATOM 3840 C CD  . GLN B 2 82  ? 26.081  -25.033 -138.272 1.00 74.99  ? 82  GLN B CD  1 
ATOM 3841 O OE1 . GLN B 2 82  ? 25.279  -24.216 -138.713 1.00 78.85  ? 82  GLN B OE1 1 
ATOM 3842 N NE2 . GLN B 2 82  ? 25.727  -26.014 -137.459 1.00 79.50  ? 82  GLN B NE2 1 
ATOM 3843 N N   . ASP B 2 83  ? 29.730  -21.433 -140.764 1.00 91.10  ? 83  ASP B N   1 
ATOM 3844 C CA  . ASP B 2 83  ? 29.865  -20.419 -141.801 1.00 92.99  ? 83  ASP B CA  1 
ATOM 3845 C C   . ASP B 2 83  ? 30.965  -20.803 -142.783 1.00 98.25  ? 83  ASP B C   1 
ATOM 3846 O O   . ASP B 2 83  ? 30.791  -20.684 -144.001 1.00 102.29 ? 83  ASP B O   1 
ATOM 3847 C CB  . ASP B 2 83  ? 30.137  -19.058 -141.154 1.00 96.89  ? 83  ASP B CB  1 
ATOM 3848 C CG  . ASP B 2 83  ? 30.213  -17.910 -142.156 1.00 101.96 ? 83  ASP B CG  1 
ATOM 3849 O OD1 . ASP B 2 83  ? 30.461  -18.128 -143.357 1.00 102.23 ? 83  ASP B OD1 1 
ATOM 3850 O OD2 . ASP B 2 83  ? 30.010  -16.756 -141.728 1.00 104.87 ? 83  ASP B OD2 1 
ATOM 3851 N N   . ASP B 2 84  ? 32.093  -21.297 -142.274 1.00 97.53  ? 84  ASP B N   1 
ATOM 3852 C CA  . ASP B 2 84  ? 33.208  -21.693 -143.125 1.00 96.33  ? 84  ASP B CA  1 
ATOM 3853 C C   . ASP B 2 84  ? 32.911  -22.924 -143.968 1.00 96.99  ? 84  ASP B C   1 
ATOM 3854 O O   . ASP B 2 84  ? 33.662  -23.205 -144.906 1.00 96.40  ? 84  ASP B O   1 
ATOM 3855 C CB  . ASP B 2 84  ? 34.445  -21.956 -142.271 1.00 96.25  ? 84  ASP B CB  1 
ATOM 3856 C CG  . ASP B 2 84  ? 35.374  -20.770 -142.218 1.00 103.77 ? 84  ASP B CG  1 
ATOM 3857 O OD1 . ASP B 2 84  ? 34.989  -19.695 -142.719 1.00 104.70 ? 84  ASP B OD1 1 
ATOM 3858 O OD2 . ASP B 2 84  ? 36.487  -20.911 -141.673 1.00 105.93 ? 84  ASP B OD2 1 
ATOM 3859 N N   . MET B 2 85  ? 31.850  -23.661 -143.660 1.00 94.59  ? 85  MET B N   1 
ATOM 3860 C CA  . MET B 2 85  ? 31.543  -24.886 -144.378 1.00 90.96  ? 85  MET B CA  1 
ATOM 3861 C C   . MET B 2 85  ? 31.121  -24.580 -145.810 1.00 93.99  ? 85  MET B C   1 
ATOM 3862 O O   . MET B 2 85  ? 30.666  -23.481 -146.132 1.00 97.19  ? 85  MET B O   1 
ATOM 3863 C CB  . MET B 2 85  ? 30.429  -25.650 -143.667 1.00 91.68  ? 85  MET B CB  1 
ATOM 3864 C CG  . MET B 2 85  ? 30.908  -26.766 -142.775 1.00 92.83  ? 85  MET B CG  1 
ATOM 3865 S SD  . MET B 2 85  ? 29.550  -27.524 -141.877 1.00 102.78 ? 85  MET B SD  1 
ATOM 3866 C CE  . MET B 2 85  ? 30.330  -27.831 -140.300 1.00 94.90  ? 85  MET B CE  1 
ATOM 3867 N N   . GLU B 2 86  ? 31.282  -25.574 -146.679 1.00 105.33 ? 86  GLU B N   1 
ATOM 3868 C CA  . GLU B 2 86  ? 30.759  -25.465 -148.030 1.00 104.63 ? 86  GLU B CA  1 
ATOM 3869 C C   . GLU B 2 86  ? 29.239  -25.605 -148.012 1.00 108.55 ? 86  GLU B C   1 
ATOM 3870 O O   . GLU B 2 86  ? 28.621  -25.841 -146.973 1.00 115.42 ? 86  GLU B O   1 
ATOM 3871 C CB  . GLU B 2 86  ? 31.387  -26.512 -148.937 1.00 30.00  ? 86  GLU B CB  1 
ATOM 3872 N N   . LEU B 2 87  ? 28.627  -25.447 -149.186 1.00 95.17  ? 87  LEU B N   1 
ATOM 3873 C CA  . LEU B 2 87  ? 27.184  -25.639 -149.273 1.00 95.10  ? 87  LEU B CA  1 
ATOM 3874 C C   . LEU B 2 87  ? 26.807  -27.109 -149.182 1.00 97.27  ? 87  LEU B C   1 
ATOM 3875 O O   . LEU B 2 87  ? 25.784  -27.449 -148.581 1.00 97.23  ? 87  LEU B O   1 
ATOM 3876 C CB  . LEU B 2 87  ? 26.647  -25.048 -150.570 1.00 92.06  ? 87  LEU B CB  1 
ATOM 3877 C CG  . LEU B 2 87  ? 26.908  -23.562 -150.769 1.00 96.05  ? 87  LEU B CG  1 
ATOM 3878 C CD1 . LEU B 2 87  ? 26.254  -23.103 -152.049 1.00 98.35  ? 87  LEU B CD1 1 
ATOM 3879 C CD2 . LEU B 2 87  ? 26.393  -22.776 -149.585 1.00 94.45  ? 87  LEU B CD2 1 
ATOM 3880 N N   . GLU B 2 88  ? 27.624  -27.991 -149.750 1.00 111.22 ? 88  GLU B N   1 
ATOM 3881 C CA  . GLU B 2 88  ? 27.280  -29.400 -149.852 1.00 112.74 ? 88  GLU B CA  1 
ATOM 3882 C C   . GLU B 2 88  ? 27.209  -30.101 -148.506 1.00 111.88 ? 88  GLU B C   1 
ATOM 3883 O O   . GLU B 2 88  ? 26.605  -31.175 -148.420 1.00 111.99 ? 88  GLU B O   1 
ATOM 3884 C CB  . GLU B 2 88  ? 28.290  -30.118 -150.747 1.00 112.94 ? 88  GLU B CB  1 
ATOM 3885 C CG  . GLU B 2 88  ? 28.077  -29.922 -152.243 1.00 113.02 ? 88  GLU B CG  1 
ATOM 3886 C CD  . GLU B 2 88  ? 28.320  -28.498 -152.727 1.00 115.05 ? 88  GLU B CD  1 
ATOM 3887 O OE1 . GLU B 2 88  ? 28.484  -27.579 -151.898 1.00 118.42 ? 88  GLU B OE1 1 
ATOM 3888 O OE2 . GLU B 2 88  ? 28.343  -28.298 -153.959 1.00 113.47 ? 88  GLU B OE2 1 
ATOM 3889 N N   . GLU B 2 89  ? 27.805  -29.538 -147.464 1.00 108.88 ? 89  GLU B N   1 
ATOM 3890 C CA  . GLU B 2 89  ? 27.739  -30.151 -146.149 1.00 108.58 ? 89  GLU B CA  1 
ATOM 3891 C C   . GLU B 2 89  ? 26.446  -29.751 -145.451 1.00 110.89 ? 89  GLU B C   1 
ATOM 3892 O O   . GLU B 2 89  ? 25.936  -28.643 -145.619 1.00 110.53 ? 89  GLU B O   1 
ATOM 3893 C CB  . GLU B 2 89  ? 28.951  -29.753 -145.309 1.00 107.32 ? 89  GLU B CB  1 
ATOM 3894 C CG  . GLU B 2 89  ? 30.238  -29.689 -146.106 1.00 111.26 ? 89  GLU B CG  1 
ATOM 3895 C CD  . GLU B 2 89  ? 31.351  -28.974 -145.370 1.00 114.42 ? 89  GLU B CD  1 
ATOM 3896 O OE1 . GLU B 2 89  ? 31.725  -29.434 -144.272 1.00 113.44 ? 89  GLU B OE1 1 
ATOM 3897 O OE2 . GLU B 2 89  ? 31.838  -27.943 -145.881 1.00 114.30 ? 89  GLU B OE2 1 
ATOM 3898 N N   . ASP B 2 90  ? 25.914  -30.681 -144.667 1.00 114.73 ? 90  ASP B N   1 
ATOM 3899 C CA  . ASP B 2 90  ? 24.657  -30.463 -143.967 1.00 110.99 ? 90  ASP B CA  1 
ATOM 3900 C C   . ASP B 2 90  ? 24.881  -29.555 -142.766 1.00 109.78 ? 90  ASP B C   1 
ATOM 3901 O O   . ASP B 2 90  ? 25.815  -29.760 -141.986 1.00 109.85 ? 90  ASP B O   1 
ATOM 3902 C CB  . ASP B 2 90  ? 24.061  -31.796 -143.531 1.00 108.00 ? 90  ASP B CB  1 
ATOM 3903 C CG  . ASP B 2 90  ? 25.042  -32.636 -142.750 1.00 114.07 ? 90  ASP B CG  1 
ATOM 3904 O OD1 . ASP B 2 90  ? 26.260  -32.404 -142.903 1.00 119.95 ? 90  ASP B OD1 1 
ATOM 3905 O OD2 . ASP B 2 90  ? 24.605  -33.536 -142.004 1.00 113.35 ? 90  ASP B OD2 1 
ATOM 3906 N N   . ILE B 2 91  ? 24.015  -28.559 -142.618 1.00 86.26  ? 91  ILE B N   1 
ATOM 3907 C CA  . ILE B 2 91  ? 24.072  -27.611 -141.518 1.00 81.40  ? 91  ILE B CA  1 
ATOM 3908 C C   . ILE B 2 91  ? 22.862  -27.738 -140.610 1.00 87.30  ? 91  ILE B C   1 
ATOM 3909 O O   . ILE B 2 91  ? 22.608  -26.850 -139.793 1.00 90.23  ? 91  ILE B O   1 
ATOM 3910 C CB  . ILE B 2 91  ? 24.206  -26.175 -142.035 1.00 79.17  ? 91  ILE B CB  1 
ATOM 3911 C CG1 . ILE B 2 91  ? 22.987  -25.822 -142.881 1.00 83.04  ? 91  ILE B CG1 1 
ATOM 3912 C CG2 . ILE B 2 91  ? 25.472  -26.023 -142.847 1.00 84.28  ? 91  ILE B CG2 1 
ATOM 3913 C CD1 . ILE B 2 91  ? 22.502  -24.407 -142.691 1.00 85.15  ? 91  ILE B CD1 1 
ATOM 3914 N N   . SER B 2 92  ? 22.101  -28.818 -140.736 1.00 87.76  ? 92  SER B N   1 
ATOM 3915 C CA  . SER B 2 92  ? 20.864  -28.997 -140.000 1.00 82.88  ? 92  SER B CA  1 
ATOM 3916 C C   . SER B 2 92  ? 20.883  -30.318 -139.247 1.00 83.39  ? 92  SER B C   1 
ATOM 3917 O O   . SER B 2 92  ? 21.515  -31.287 -139.673 1.00 88.40  ? 92  SER B O   1 
ATOM 3918 C CB  . SER B 2 92  ? 19.665  -28.962 -140.938 1.00 79.98  ? 92  SER B CB  1 
ATOM 3919 O OG  . SER B 2 92  ? 19.814  -29.920 -141.966 1.00 84.78  ? 92  SER B OG  1 
ATOM 3920 N N   . SER B 2 93  ? 20.179  -30.346 -138.119 1.00 78.76  ? 93  SER B N   1 
ATOM 3921 C CA  . SER B 2 93  ? 20.031  -31.557 -137.331 1.00 74.19  ? 93  SER B CA  1 
ATOM 3922 C C   . SER B 2 93  ? 18.734  -31.473 -136.545 1.00 73.34  ? 93  SER B C   1 
ATOM 3923 O O   . SER B 2 93  ? 18.171  -30.393 -136.356 1.00 81.23  ? 93  SER B O   1 
ATOM 3924 C CB  . SER B 2 93  ? 21.215  -31.768 -136.388 1.00 74.00  ? 93  SER B CB  1 
ATOM 3925 O OG  . SER B 2 93  ? 21.087  -32.987 -135.683 1.00 74.43  ? 93  SER B OG  1 
ATOM 3926 N N   . ASN B 2 94  ? 18.265  -32.627 -136.088 1.00 59.42  ? 94  ASN B N   1 
ATOM 3927 C CA  . ASN B 2 94  ? 17.009  -32.685 -135.356 1.00 56.16  ? 94  ASN B CA  1 
ATOM 3928 C C   . ASN B 2 94  ? 17.132  -31.942 -134.035 1.00 66.45  ? 94  ASN B C   1 
ATOM 3929 O O   . ASN B 2 94  ? 18.065  -32.178 -133.267 1.00 81.20  ? 94  ASN B O   1 
ATOM 3930 C CB  . ASN B 2 94  ? 16.619  -34.133 -135.093 1.00 65.09  ? 94  ASN B CB  1 
ATOM 3931 C CG  . ASN B 2 94  ? 15.640  -34.659 -136.102 1.00 72.79  ? 94  ASN B CG  1 
ATOM 3932 O OD1 . ASN B 2 94  ? 15.424  -34.050 -137.145 1.00 75.33  ? 94  ASN B OD1 1 
ATOM 3933 N ND2 . ASN B 2 94  ? 15.032  -35.795 -135.797 1.00 72.70  ? 94  ASN B ND2 1 
ATOM 3934 N N   . PHE B 2 95  ? 16.183  -31.052 -133.764 1.00 57.75  ? 95  PHE B N   1 
ATOM 3935 C CA  . PHE B 2 95  ? 16.129  -30.342 -132.492 1.00 59.74  ? 95  PHE B CA  1 
ATOM 3936 C C   . PHE B 2 95  ? 15.313  -31.183 -131.523 1.00 70.06  ? 95  PHE B C   1 
ATOM 3937 O O   . PHE B 2 95  ? 14.107  -31.361 -131.710 1.00 78.53  ? 95  PHE B O   1 
ATOM 3938 C CB  . PHE B 2 95  ? 15.520  -28.956 -132.663 1.00 65.16  ? 95  PHE B CB  1 
ATOM 3939 C CG  . PHE B 2 95  ? 15.832  -28.019 -131.537 1.00 68.19  ? 95  PHE B CG  1 
ATOM 3940 C CD1 . PHE B 2 95  ? 16.981  -27.260 -131.554 1.00 64.12  ? 95  PHE B CD1 1 
ATOM 3941 C CD2 . PHE B 2 95  ? 14.980  -27.901 -130.462 1.00 68.69  ? 95  PHE B CD2 1 
ATOM 3942 C CE1 . PHE B 2 95  ? 17.269  -26.403 -130.522 1.00 64.03  ? 95  PHE B CE1 1 
ATOM 3943 C CE2 . PHE B 2 95  ? 15.267  -27.044 -129.429 1.00 70.09  ? 95  PHE B CE2 1 
ATOM 3944 C CZ  . PHE B 2 95  ? 16.412  -26.296 -129.461 1.00 67.16  ? 95  PHE B CZ  1 
ATOM 3945 N N   . VAL B 2 96  ? 15.965  -31.697 -130.487 1.00 74.47  ? 96  VAL B N   1 
ATOM 3946 C CA  . VAL B 2 96  ? 15.366  -32.661 -129.574 1.00 68.75  ? 96  VAL B CA  1 
ATOM 3947 C C   . VAL B 2 96  ? 15.089  -31.971 -128.250 1.00 73.45  ? 96  VAL B C   1 
ATOM 3948 O O   . VAL B 2 96  ? 15.964  -31.296 -127.700 1.00 80.75  ? 96  VAL B O   1 
ATOM 3949 C CB  . VAL B 2 96  ? 16.277  -33.884 -129.380 1.00 68.44  ? 96  VAL B CB  1 
ATOM 3950 C CG1 . VAL B 2 96  ? 16.057  -34.505 -128.020 1.00 71.51  ? 96  VAL B CG1 1 
ATOM 3951 C CG2 . VAL B 2 96  ? 16.021  -34.892 -130.464 1.00 70.49  ? 96  VAL B CG2 1 
ATOM 3952 N N   . ILE B 2 97  ? 13.869  -32.130 -127.749 1.00 73.55  ? 97  ILE B N   1 
ATOM 3953 C CA  . ILE B 2 97  ? 13.463  -31.607 -126.453 1.00 74.29  ? 97  ILE B CA  1 
ATOM 3954 C C   . ILE B 2 97  ? 13.019  -32.777 -125.592 1.00 73.20  ? 97  ILE B C   1 
ATOM 3955 O O   . ILE B 2 97  ? 12.143  -33.549 -125.998 1.00 78.45  ? 97  ILE B O   1 
ATOM 3956 C CB  . ILE B 2 97  ? 12.330  -30.576 -126.590 1.00 74.20  ? 97  ILE B CB  1 
ATOM 3957 C CG1 . ILE B 2 97  ? 12.801  -29.381 -127.409 1.00 71.87  ? 97  ILE B CG1 1 
ATOM 3958 C CG2 . ILE B 2 97  ? 11.862  -30.126 -125.225 1.00 71.16  ? 97  ILE B CG2 1 
ATOM 3959 C CD1 . ILE B 2 97  ? 11.687  -28.653 -128.103 1.00 73.85  ? 97  ILE B CD1 1 
ATOM 3960 N N   . TYR B 2 98  ? 13.617  -32.912 -124.417 1.00 78.52  ? 98  TYR B N   1 
ATOM 3961 C CA  . TYR B 2 98  ? 13.244  -33.957 -123.467 1.00 78.74  ? 98  TYR B CA  1 
ATOM 3962 C C   . TYR B 2 98  ? 12.431  -33.308 -122.360 1.00 81.91  ? 98  TYR B C   1 
ATOM 3963 O O   . TYR B 2 98  ? 12.977  -32.606 -121.506 1.00 86.73  ? 98  TYR B O   1 
ATOM 3964 C CB  . TYR B 2 98  ? 14.464  -34.665 -122.898 1.00 80.98  ? 98  TYR B CB  1 
ATOM 3965 C CG  . TYR B 2 98  ? 14.137  -35.497 -121.682 1.00 82.81  ? 98  TYR B CG  1 
ATOM 3966 C CD1 . TYR B 2 98  ? 13.327  -36.615 -121.784 1.00 83.10  ? 98  TYR B CD1 1 
ATOM 3967 C CD2 . TYR B 2 98  ? 14.630  -35.161 -120.433 1.00 85.83  ? 98  TYR B CD2 1 
ATOM 3968 C CE1 . TYR B 2 98  ? 13.020  -37.377 -120.679 1.00 83.75  ? 98  TYR B CE1 1 
ATOM 3969 C CE2 . TYR B 2 98  ? 14.328  -35.918 -119.323 1.00 86.87  ? 98  TYR B CE2 1 
ATOM 3970 C CZ  . TYR B 2 98  ? 13.523  -37.023 -119.452 1.00 85.61  ? 98  TYR B CZ  1 
ATOM 3971 O OH  . TYR B 2 98  ? 13.219  -37.781 -118.349 1.00 87.16  ? 98  TYR B OH  1 
ATOM 3972 N N   . ASP B 2 99  ? 11.126  -33.546 -122.374 1.00 90.11  ? 99  ASP B N   1 
ATOM 3973 C CA  . ASP B 2 99  ? 10.217  -33.000 -121.371 1.00 87.55  ? 99  ASP B CA  1 
ATOM 3974 C C   . ASP B 2 99  ? 9.362   -34.127 -120.821 1.00 91.62  ? 99  ASP B C   1 
ATOM 3975 O O   . ASP B 2 99  ? 8.491   -34.647 -121.547 1.00 94.54  ? 99  ASP B O   1 
ATOM 3976 C CB  . ASP B 2 99  ? 9.345   -31.904 -121.967 1.00 86.12  ? 99  ASP B CB  1 
ATOM 3977 C CG  . ASP B 2 99  ? 8.420   -31.290 -120.954 1.00 92.78  ? 99  ASP B CG  1 
ATOM 3978 O OD1 . ASP B 2 99  ? 8.674   -31.444 -119.743 1.00 90.12  ? 99  ASP B OD1 1 
ATOM 3979 O OD2 . ASP B 2 99  ? 7.429   -30.660 -121.367 1.00 99.52  ? 99  ASP B OD2 1 
ATOM 3980 N N   . PRO B 2 100 ? 9.560   -34.536 -119.565 1.00 83.25  ? 100 PRO B N   1 
ATOM 3981 C CA  . PRO B 2 100 ? 8.748   -35.627 -119.015 1.00 84.15  ? 100 PRO B CA  1 
ATOM 3982 C C   . PRO B 2 100 ? 7.349   -35.197 -118.633 1.00 83.99  ? 100 PRO B C   1 
ATOM 3983 O O   . PRO B 2 100 ? 6.511   -36.060 -118.350 1.00 85.96  ? 100 PRO B O   1 
ATOM 3984 C CB  . PRO B 2 100 ? 9.543   -36.076 -117.784 1.00 82.15  ? 100 PRO B CB  1 
ATOM 3985 C CG  . PRO B 2 100 ? 10.570  -35.013 -117.536 1.00 80.41  ? 100 PRO B CG  1 
ATOM 3986 C CD  . PRO B 2 100 ? 10.437  -33.933 -118.556 1.00 79.97  ? 100 PRO B CD  1 
ATOM 3987 N N   . SER B 2 101 ? 7.071   -33.897 -118.614 1.00 81.56  ? 101 SER B N   1 
ATOM 3988 C CA  . SER B 2 101 ? 5.748   -33.409 -118.260 1.00 83.42  ? 101 SER B CA  1 
ATOM 3989 C C   . SER B 2 101 ? 4.762   -33.491 -119.411 1.00 81.95  ? 101 SER B C   1 
ATOM 3990 O O   . SER B 2 101 ? 3.556   -33.361 -119.185 1.00 82.24  ? 101 SER B O   1 
ATOM 3991 C CB  . SER B 2 101 ? 5.836   -31.963 -117.782 1.00 85.54  ? 101 SER B CB  1 
ATOM 3992 O OG  . SER B 2 101 ? 6.025   -31.089 -118.877 1.00 84.43  ? 101 SER B OG  1 
ATOM 3993 N N   . GLY B 2 102 ? 5.238   -33.690 -120.635 1.00 75.93  ? 102 GLY B N   1 
ATOM 3994 C CA  . GLY B 2 102 ? 4.350   -33.603 -121.769 1.00 71.31  ? 102 GLY B CA  1 
ATOM 3995 C C   . GLY B 2 102 ? 3.908   -32.199 -122.101 1.00 73.88  ? 102 GLY B C   1 
ATOM 3996 O O   . GLY B 2 102 ? 3.016   -32.026 -122.935 1.00 76.35  ? 102 GLY B O   1 
ATOM 3997 N N   . SER B 2 103 ? 4.497   -31.188 -121.460 1.00 76.93  ? 103 SER B N   1 
ATOM 3998 C CA  . SER B 2 103 ? 4.110   -29.811 -121.740 1.00 78.73  ? 103 SER B CA  1 
ATOM 3999 C C   . SER B 2 103 ? 4.428   -29.437 -123.178 1.00 81.79  ? 103 SER B C   1 
ATOM 4000 O O   . SER B 2 103 ? 3.606   -28.820 -123.862 1.00 89.18  ? 103 SER B O   1 
ATOM 4001 C CB  . SER B 2 103 ? 4.811   -28.860 -120.771 1.00 80.87  ? 103 SER B CB  1 
ATOM 4002 O OG  . SER B 2 103 ? 4.012   -27.725 -120.490 1.00 80.24  ? 103 SER B OG  1 
ATOM 4003 N N   . VAL B 2 104 ? 5.598   -29.805 -123.653 1.00 74.38  ? 104 VAL B N   1 
ATOM 4004 C CA  . VAL B 2 104 ? 5.974   -29.558 -125.037 1.00 73.82  ? 104 VAL B CA  1 
ATOM 4005 C C   . VAL B 2 104 ? 5.484   -30.725 -125.878 1.00 79.87  ? 104 VAL B C   1 
ATOM 4006 O O   . VAL B 2 104 ? 5.391   -31.862 -125.400 1.00 82.81  ? 104 VAL B O   1 
ATOM 4007 C CB  . VAL B 2 104 ? 7.495   -29.357 -125.168 1.00 73.24  ? 104 VAL B CB  1 
ATOM 4008 C CG1 . VAL B 2 104 ? 8.215   -30.687 -125.203 1.00 75.55  ? 104 VAL B CG1 1 
ATOM 4009 C CG2 . VAL B 2 104 ? 7.812   -28.551 -126.396 1.00 76.42  ? 104 VAL B CG2 1 
ATOM 4010 N N   . LEU B 2 105 ? 5.147   -30.445 -127.134 1.00 81.80  ? 105 LEU B N   1 
ATOM 4011 C CA  . LEU B 2 105 ? 4.571   -31.450 -128.013 1.00 83.10  ? 105 LEU B CA  1 
ATOM 4012 C C   . LEU B 2 105 ? 5.404   -31.724 -129.252 1.00 82.83  ? 105 LEU B C   1 
ATOM 4013 O O   . LEU B 2 105 ? 5.184   -32.746 -129.907 1.00 84.56  ? 105 LEU B O   1 
ATOM 4014 C CB  . LEU B 2 105 ? 3.167   -31.023 -128.460 1.00 84.37  ? 105 LEU B CB  1 
ATOM 4015 C CG  . LEU B 2 105 ? 2.009   -31.150 -127.474 1.00 81.32  ? 105 LEU B CG  1 
ATOM 4016 C CD1 . LEU B 2 105 ? 1.835   -29.864 -126.702 1.00 80.38  ? 105 LEU B CD1 1 
ATOM 4017 C CD2 . LEU B 2 105 ? 0.734   -31.492 -128.212 1.00 80.63  ? 105 LEU B CD2 1 
ATOM 4018 N N   . ALA B 2 106 ? 6.350   -30.856 -129.582 1.00 84.62  ? 106 ALA B N   1 
ATOM 4019 C CA  . ALA B 2 106 ? 6.995   -30.871 -130.880 1.00 85.62  ? 106 ALA B CA  1 
ATOM 4020 C C   . ALA B 2 106 ? 8.477   -31.186 -130.757 1.00 86.66  ? 106 ALA B C   1 
ATOM 4021 O O   . ALA B 2 106 ? 9.117   -30.875 -129.750 1.00 90.12  ? 106 ALA B O   1 
ATOM 4022 C CB  . ALA B 2 106 ? 6.818   -29.530 -131.588 1.00 87.87  ? 106 ALA B CB  1 
ATOM 4023 N N   . THR B 2 107 ? 9.009   -31.824 -131.792 1.00 83.56  ? 107 THR B N   1 
ATOM 4024 C CA  . THR B 2 107 ? 10.441  -31.993 -131.971 1.00 81.09  ? 107 THR B CA  1 
ATOM 4025 C C   . THR B 2 107 ? 10.823  -31.443 -133.335 1.00 76.62  ? 107 THR B C   1 
ATOM 4026 O O   . THR B 2 107 ? 10.219  -31.803 -134.348 1.00 78.69  ? 107 THR B O   1 
ATOM 4027 C CB  . THR B 2 107 ? 10.862  -33.460 -131.876 1.00 83.40  ? 107 THR B CB  1 
ATOM 4028 O OG1 . THR B 2 107 ? 10.786  -34.062 -133.173 1.00 83.60  ? 107 THR B OG1 1 
ATOM 4029 C CG2 . THR B 2 107 ? 9.956   -34.217 -130.924 1.00 83.72  ? 107 THR B CG2 1 
ATOM 4030 N N   . GLY B 2 108 ? 11.822  -30.573 -133.361 1.00 75.53  ? 108 GLY B N   1 
ATOM 4031 C CA  . GLY B 2 108 ? 12.220  -29.946 -134.603 1.00 77.73  ? 108 GLY B CA  1 
ATOM 4032 C C   . GLY B 2 108 ? 12.917  -30.890 -135.554 1.00 82.72  ? 108 GLY B C   1 
ATOM 4033 O O   . GLY B 2 108 ? 13.964  -31.447 -135.221 1.00 89.05  ? 108 GLY B O   1 
ATOM 4034 N N   . ILE B 2 109 ? 12.357  -31.072 -136.742 1.00 72.18  ? 109 ILE B N   1 
ATOM 4035 C CA  . ILE B 2 109 ? 12.915  -31.983 -137.733 1.00 71.82  ? 109 ILE B CA  1 
ATOM 4036 C C   . ILE B 2 109 ? 13.769  -31.175 -138.700 1.00 79.42  ? 109 ILE B C   1 
ATOM 4037 O O   . ILE B 2 109 ? 13.290  -30.207 -139.300 1.00 85.66  ? 109 ILE B O   1 
ATOM 4038 C CB  . ILE B 2 109 ? 11.808  -32.737 -138.478 1.00 73.04  ? 109 ILE B CB  1 
ATOM 4039 C CG1 . ILE B 2 109 ? 11.165  -33.774 -137.563 1.00 73.76  ? 109 ILE B CG1 1 
ATOM 4040 C CG2 . ILE B 2 109 ? 12.373  -33.423 -139.694 1.00 74.89  ? 109 ILE B CG2 1 
ATOM 4041 C CD1 . ILE B 2 109 ? 12.139  -34.744 -136.972 1.00 71.36  ? 109 ILE B CD1 1 
ATOM 4042 N N   . ASN B 2 110 ? 15.030  -31.573 -138.854 1.00 80.09  ? 110 ASN B N   1 
ATOM 4043 C CA  . ASN B 2 110 ? 15.987  -30.869 -139.703 1.00 77.31  ? 110 ASN B CA  1 
ATOM 4044 C C   . ASN B 2 110 ? 16.077  -29.395 -139.328 1.00 80.48  ? 110 ASN B C   1 
ATOM 4045 O O   . ASN B 2 110 ? 16.012  -28.507 -140.176 1.00 86.05  ? 110 ASN B O   1 
ATOM 4046 C CB  . ASN B 2 110 ? 15.638  -31.034 -141.180 1.00 74.42  ? 110 ASN B CB  1 
ATOM 4047 C CG  . ASN B 2 110 ? 16.125  -32.341 -141.748 1.00 80.56  ? 110 ASN B CG  1 
ATOM 4048 O OD1 . ASN B 2 110 ? 17.115  -32.898 -141.285 1.00 85.82  ? 110 ASN B OD1 1 
ATOM 4049 N ND2 . ASN B 2 110 ? 15.435  -32.839 -142.764 1.00 83.37  ? 110 ASN B ND2 1 
ATOM 4050 N N   . ALA B 2 111 ? 16.226  -29.138 -138.035 1.00 72.84  ? 111 ALA B N   1 
ATOM 4051 C CA  . ALA B 2 111 ? 16.331  -27.774 -137.544 1.00 64.40  ? 111 ALA B CA  1 
ATOM 4052 C C   . ALA B 2 111 ? 17.676  -27.173 -137.915 1.00 74.93  ? 111 ALA B C   1 
ATOM 4053 O O   . ALA B 2 111 ? 18.693  -27.867 -137.951 1.00 83.24  ? 111 ALA B O   1 
ATOM 4054 C CB  . ALA B 2 111 ? 16.150  -27.735 -136.030 1.00 64.80  ? 111 ALA B CB  1 
ATOM 4055 N N   . TRP B 2 112 ? 17.675  -25.874 -138.192 1.00 76.96  ? 112 TRP B N   1 
ATOM 4056 C CA  . TRP B 2 112 ? 18.881  -25.138 -138.537 1.00 66.19  ? 112 TRP B CA  1 
ATOM 4057 C C   . TRP B 2 112 ? 18.897  -23.820 -137.782 1.00 70.72  ? 112 TRP B C   1 
ATOM 4058 O O   . TRP B 2 112 ? 17.850  -23.292 -137.405 1.00 84.00  ? 112 TRP B O   1 
ATOM 4059 C CB  . TRP B 2 112 ? 18.962  -24.867 -140.035 1.00 67.13  ? 112 TRP B CB  1 
ATOM 4060 C CG  . TRP B 2 112 ? 17.826  -24.050 -140.546 1.00 71.30  ? 112 TRP B CG  1 
ATOM 4061 C CD1 . TRP B 2 112 ? 17.692  -22.701 -140.471 1.00 71.20  ? 112 TRP B CD1 1 
ATOM 4062 C CD2 . TRP B 2 112 ? 16.662  -24.530 -141.219 1.00 70.79  ? 112 TRP B CD2 1 
ATOM 4063 N NE1 . TRP B 2 112 ? 16.515  -22.309 -141.051 1.00 69.60  ? 112 TRP B NE1 1 
ATOM 4064 C CE2 . TRP B 2 112 ? 15.865  -23.417 -141.519 1.00 71.86  ? 112 TRP B CE2 1 
ATOM 4065 C CE3 . TRP B 2 112 ? 16.217  -25.796 -141.597 1.00 73.07  ? 112 TRP B CE3 1 
ATOM 4066 C CZ2 . TRP B 2 112 ? 14.651  -23.529 -142.177 1.00 75.92  ? 112 TRP B CZ2 1 
ATOM 4067 C CZ3 . TRP B 2 112 ? 15.012  -25.905 -142.249 1.00 69.21  ? 112 TRP B CZ3 1 
ATOM 4068 C CH2 . TRP B 2 112 ? 14.243  -24.781 -142.534 1.00 72.58  ? 112 TRP B CH2 1 
ATOM 4069 N N   . LEU B 2 113 ? 20.093  -23.290 -137.569 1.00 62.57  ? 113 LEU B N   1 
ATOM 4070 C CA  . LEU B 2 113 ? 20.238  -22.011 -136.892 1.00 67.87  ? 113 LEU B CA  1 
ATOM 4071 C C   . LEU B 2 113 ? 19.865  -20.889 -137.850 1.00 68.23  ? 113 LEU B C   1 
ATOM 4072 O O   . LEU B 2 113 ? 20.316  -20.872 -138.996 1.00 76.60  ? 113 LEU B O   1 
ATOM 4073 C CB  . LEU B 2 113 ? 21.668  -21.846 -136.388 1.00 65.98  ? 113 LEU B CB  1 
ATOM 4074 C CG  . LEU B 2 113 ? 22.003  -20.623 -135.548 1.00 64.67  ? 113 LEU B CG  1 
ATOM 4075 C CD1 . LEU B 2 113 ? 21.290  -20.689 -134.228 1.00 64.90  ? 113 LEU B CD1 1 
ATOM 4076 C CD2 . LEU B 2 113 ? 23.491  -20.574 -135.326 1.00 68.90  ? 113 LEU B CD2 1 
ATOM 4077 N N   . GLN B 2 114 ? 19.034  -19.958 -137.390 1.00 67.52  ? 114 GLN B N   1 
ATOM 4078 C CA  . GLN B 2 114 ? 18.510  -18.916 -138.262 1.00 69.20  ? 114 GLN B CA  1 
ATOM 4079 C C   . GLN B 2 114 ? 19.010  -17.528 -137.892 1.00 79.07  ? 114 GLN B C   1 
ATOM 4080 O O   . GLN B 2 114 ? 19.578  -16.833 -138.737 1.00 87.16  ? 114 GLN B O   1 
ATOM 4081 C CB  . GLN B 2 114 ? 16.981  -18.934 -138.253 1.00 71.75  ? 114 GLN B CB  1 
ATOM 4082 C CG  . GLN B 2 114 ? 16.381  -18.606 -139.595 1.00 72.26  ? 114 GLN B CG  1 
ATOM 4083 C CD  . GLN B 2 114 ? 14.881  -18.513 -139.549 1.00 78.00  ? 114 GLN B CD  1 
ATOM 4084 O OE1 . GLN B 2 114 ? 14.272  -18.692 -138.501 1.00 78.63  ? 114 GLN B OE1 1 
ATOM 4085 N NE2 . GLN B 2 114 ? 14.274  -18.241 -140.690 1.00 82.88  ? 114 GLN B NE2 1 
ATOM 4086 N N   . GLU B 2 115 ? 18.809  -17.094 -136.655 1.00 84.01  ? 115 GLU B N   1 
ATOM 4087 C CA  . GLU B 2 115 ? 19.166  -15.744 -136.250 1.00 82.57  ? 115 GLU B CA  1 
ATOM 4088 C C   . GLU B 2 115 ? 20.078  -15.780 -135.037 1.00 80.62  ? 115 GLU B C   1 
ATOM 4089 O O   . GLU B 2 115 ? 19.827  -16.516 -134.081 1.00 90.69  ? 115 GLU B O   1 
ATOM 4090 C CB  . GLU B 2 115 ? 17.926  -14.916 -135.932 1.00 79.79  ? 115 GLU B CB  1 
ATOM 4091 C CG  . GLU B 2 115 ? 16.962  -14.794 -137.087 1.00 89.56  ? 115 GLU B CG  1 
ATOM 4092 C CD  . GLU B 2 115 ? 16.170  -13.511 -137.040 1.00 96.49  ? 115 GLU B CD  1 
ATOM 4093 O OE1 . GLU B 2 115 ? 16.236  -12.817 -136.007 1.00 99.86  ? 115 GLU B OE1 1 
ATOM 4094 O OE2 . GLU B 2 115 ? 15.480  -13.197 -138.032 1.00 98.03  ? 115 GLU B OE2 1 
ATOM 4095 N N   . LEU B 2 116 ? 21.136  -14.982 -135.087 1.00 61.91  ? 116 LEU B N   1 
ATOM 4096 C CA  . LEU B 2 116 ? 21.993  -14.815 -133.933 1.00 61.47  ? 116 LEU B CA  1 
ATOM 4097 C C   . LEU B 2 116 ? 21.274  -13.986 -132.873 1.00 70.46  ? 116 LEU B C   1 
ATOM 4098 O O   . LEU B 2 116 ? 20.380  -13.201 -133.192 1.00 80.11  ? 116 LEU B O   1 
ATOM 4099 C CB  . LEU B 2 116 ? 23.294  -14.137 -134.338 1.00 64.15  ? 116 LEU B CB  1 
ATOM 4100 C CG  . LEU B 2 116 ? 24.221  -14.975 -135.209 1.00 66.82  ? 116 LEU B CG  1 
ATOM 4101 C CD1 . LEU B 2 116 ? 25.457  -14.182 -135.561 1.00 69.78  ? 116 LEU B CD1 1 
ATOM 4102 C CD2 . LEU B 2 116 ? 24.595  -16.253 -134.498 1.00 65.71  ? 116 LEU B CD2 1 
ATOM 4103 N N   . PRO B 2 117 ? 21.629  -14.150 -131.604 1.00 65.85  ? 117 PRO B N   1 
ATOM 4104 C CA  . PRO B 2 117 ? 20.978  -13.359 -130.561 1.00 66.28  ? 117 PRO B CA  1 
ATOM 4105 C C   . PRO B 2 117 ? 21.366  -11.897 -130.659 1.00 72.10  ? 117 PRO B C   1 
ATOM 4106 O O   . PRO B 2 117 ? 22.436  -11.548 -131.159 1.00 72.21  ? 117 PRO B O   1 
ATOM 4107 C CB  . PRO B 2 117 ? 21.499  -13.979 -129.265 1.00 70.50  ? 117 PRO B CB  1 
ATOM 4108 C CG  . PRO B 2 117 ? 22.772  -14.607 -129.631 1.00 66.87  ? 117 PRO B CG  1 
ATOM 4109 C CD  . PRO B 2 117 ? 22.683  -15.018 -131.060 1.00 65.97  ? 117 PRO B CD  1 
ATOM 4110 N N   . GLN B 2 118 ? 20.476  -11.037 -130.180 1.00 80.93  ? 118 GLN B N   1 
ATOM 4111 C CA  . GLN B 2 118 ? 20.774  -9.612  -130.097 1.00 79.46  ? 118 GLN B CA  1 
ATOM 4112 C C   . GLN B 2 118 ? 21.435  -9.351  -128.751 1.00 85.82  ? 118 GLN B C   1 
ATOM 4113 O O   . GLN B 2 118 ? 20.820  -9.545  -127.700 1.00 88.63  ? 118 GLN B O   1 
ATOM 4114 C CB  . GLN B 2 118 ? 19.506  -8.782  -130.266 1.00 77.50  ? 118 GLN B CB  1 
ATOM 4115 C CG  . GLN B 2 118 ? 19.536  -7.459  -129.525 1.00 82.47  ? 118 GLN B CG  1 
ATOM 4116 C CD  . GLN B 2 118 ? 18.291  -6.631  -129.754 1.00 88.25  ? 118 GLN B CD  1 
ATOM 4117 O OE1 . GLN B 2 118 ? 17.201  -7.169  -129.941 1.00 90.13  ? 118 GLN B OE1 1 
ATOM 4118 N NE2 . GLN B 2 118 ? 18.445  -5.314  -129.736 1.00 87.66  ? 118 GLN B NE2 1 
ATOM 4119 N N   . ILE B 2 119 ? 22.695  -8.934  -128.780 1.00 77.56  ? 119 ILE B N   1 
ATOM 4120 C CA  . ILE B 2 119 ? 23.452  -8.714  -127.555 1.00 68.36  ? 119 ILE B CA  1 
ATOM 4121 C C   . ILE B 2 119 ? 23.043  -7.373  -126.969 1.00 72.03  ? 119 ILE B C   1 
ATOM 4122 O O   . ILE B 2 119 ? 23.086  -6.349  -127.656 1.00 79.40  ? 119 ILE B O   1 
ATOM 4123 C CB  . ILE B 2 119 ? 24.963  -8.761  -127.810 1.00 62.89  ? 119 ILE B CB  1 
ATOM 4124 C CG1 . ILE B 2 119 ? 25.403  -10.132 -128.324 1.00 69.45  ? 119 ILE B CG1 1 
ATOM 4125 C CG2 . ILE B 2 119 ? 25.712  -8.420  -126.550 1.00 71.43  ? 119 ILE B CG2 1 
ATOM 4126 C CD1 . ILE B 2 119 ? 25.259  -10.328 -129.813 1.00 73.07  ? 119 ILE B CD1 1 
ATOM 4127 N N   . GLU B 2 120 ? 22.637  -7.376  -125.703 1.00 75.05  ? 120 GLU B N   1 
ATOM 4128 C CA  . GLU B 2 120 ? 22.263  -6.155  -125.006 1.00 81.53  ? 120 GLU B CA  1 
ATOM 4129 C C   . GLU B 2 120 ? 22.863  -6.176  -123.611 1.00 84.60  ? 120 GLU B C   1 
ATOM 4130 O O   . GLU B 2 120 ? 22.769  -7.187  -122.909 1.00 89.53  ? 120 GLU B O   1 
ATOM 4131 C CB  . GLU B 2 120 ? 20.744  -6.000  -124.930 1.00 77.07  ? 120 GLU B CB  1 
ATOM 4132 C CG  . GLU B 2 120 ? 20.296  -5.028  -123.865 1.00 81.31  ? 120 GLU B CG  1 
ATOM 4133 C CD  . GLU B 2 120 ? 19.217  -4.094  -124.353 1.00 90.77  ? 120 GLU B CD  1 
ATOM 4134 O OE1 . GLU B 2 120 ? 18.656  -4.354  -125.435 1.00 95.73  ? 120 GLU B OE1 1 
ATOM 4135 O OE2 . GLU B 2 120 ? 18.933  -3.096  -123.657 1.00 90.39  ? 120 GLU B OE2 1 
ATOM 4136 N N   . LEU B 2 121 ? 23.581  -5.118  -123.264 1.00 74.22  ? 121 LEU B N   1 
ATOM 4137 C CA  . LEU B 2 121 ? 24.212  -5.064  -121.932 1.00 70.00  ? 121 LEU B CA  1 
ATOM 4138 C C   . LEU B 2 121 ? 23.519  -3.944  -121.164 1.00 77.81  ? 121 LEU B C   1 
ATOM 4139 O O   . LEU B 2 121 ? 22.945  -3.063  -121.816 1.00 84.71  ? 121 LEU B O   1 
ATOM 4140 C CB  . LEU B 2 121 ? 25.707  -4.834  -122.099 1.00 68.45  ? 121 LEU B CB  1 
ATOM 4141 C CG  . LEU B 2 121 ? 26.464  -5.911  -122.876 1.00 69.36  ? 121 LEU B CG  1 
ATOM 4142 C CD1 . LEU B 2 121 ? 27.933  -5.564  -122.917 1.00 74.38  ? 121 LEU B CD1 1 
ATOM 4143 C CD2 . LEU B 2 121 ? 26.257  -7.252  -122.212 1.00 72.88  ? 121 LEU B CD2 1 
ATOM 4144 N N   . GLY B 2 122 ? 23.531  -4.004  -119.838 1.00 85.08  ? 122 GLY B N   1 
ATOM 4145 C CA  . GLY B 2 122 ? 22.838  -2.985  -119.036 1.00 84.42  ? 122 GLY B CA  1 
ATOM 4146 C C   . GLY B 2 122 ? 23.115  -3.172  -117.565 1.00 86.06  ? 122 GLY B C   1 
ATOM 4147 O O   . GLY B 2 122 ? 23.808  -4.138  -117.222 1.00 91.57  ? 122 GLY B O   1 
ATOM 4148 N N   . ARG B 2 123 ? 22.581  -2.289  -116.722 1.00 79.42  ? 123 ARG B N   1 
ATOM 4149 C CA  . ARG B 2 123 ? 22.762  -2.423  -115.260 1.00 75.25  ? 123 ARG B CA  1 
ATOM 4150 C C   . ARG B 2 123 ? 22.148  -3.749  -114.837 1.00 78.07  ? 123 ARG B C   1 
ATOM 4151 O O   . ARG B 2 123 ? 22.572  -4.303  -113.816 1.00 86.18  ? 123 ARG B O   1 
ATOM 4152 C CB  . ARG B 2 123 ? 22.074  -1.298  -114.490 1.00 77.96  ? 123 ARG B CB  1 
ATOM 4153 C CG  . ARG B 2 123 ? 20.635  -1.029  -114.902 1.00 85.81  ? 123 ARG B CG  1 
ATOM 4154 C CD  . ARG B 2 123 ? 19.798  -0.548  -113.730 1.00 87.97  ? 123 ARG B CD  1 
ATOM 4155 N NE  . ARG B 2 123 ? 20.201  -1.196  -112.479 1.00 87.77  ? 123 ARG B NE  1 
ATOM 4156 C CZ  . ARG B 2 123 ? 20.688  -0.544  -111.436 1.00 79.76  ? 123 ARG B CZ  1 
ATOM 4157 N NH1 . ARG B 2 123 ? 20.490  -1.006  -110.216 1.00 74.62  ? 123 ARG B NH1 1 
ATOM 4158 N NH2 . ARG B 2 123 ? 21.372  0.568   -111.622 1.00 71.34  ? 123 ARG B NH2 1 
ATOM 4159 N N   . ASP B 2 124 ? 21.182  -4.230  -115.603 1.00 88.30  ? 124 ASP B N   1 
ATOM 4160 C CA  . ASP B 2 124 ? 20.569  -5.539  -115.296 1.00 90.35  ? 124 ASP B CA  1 
ATOM 4161 C C   . ASP B 2 124 ? 21.030  -6.550  -116.339 1.00 92.71  ? 124 ASP B C   1 
ATOM 4162 O O   . ASP B 2 124 ? 21.813  -6.178  -117.220 1.00 96.97  ? 124 ASP B O   1 
ATOM 4163 C CB  . ASP B 2 124 ? 19.063  -5.413  -115.247 1.00 94.20  ? 124 ASP B CB  1 
ATOM 4164 C CG  . ASP B 2 124 ? 18.518  -4.784  -113.975 1.00 101.24 ? 124 ASP B CG  1 
ATOM 4165 O OD1 . ASP B 2 124 ? 19.290  -4.071  -113.302 1.00 103.31 ? 124 ASP B OD1 1 
ATOM 4166 O OD2 . ASP B 2 124 ? 17.331  -5.018  -113.668 1.00 99.41  ? 124 ASP B OD2 1 
ATOM 4167 N N   . GLN B 2 125 ? 20.550  -7.779  -116.247 1.00 86.15  ? 125 GLN B N   1 
ATOM 4168 C CA  . GLN B 2 125 ? 20.991  -8.810  -117.173 1.00 87.77  ? 125 GLN B CA  1 
ATOM 4169 C C   . GLN B 2 125 ? 19.906  -9.063  -118.208 1.00 93.67  ? 125 GLN B C   1 
ATOM 4170 O O   . GLN B 2 125 ? 18.739  -9.263  -117.854 1.00 93.94  ? 125 GLN B O   1 
ATOM 4171 C CB  . GLN B 2 125 ? 21.317  -10.103 -116.430 1.00 87.87  ? 125 GLN B CB  1 
ATOM 4172 C CG  . GLN B 2 125 ? 22.741  -10.195 -115.948 1.00 87.29  ? 125 GLN B CG  1 
ATOM 4173 C CD  . GLN B 2 125 ? 23.000  -11.469 -115.194 1.00 90.23  ? 125 GLN B CD  1 
ATOM 4174 O OE1 . GLN B 2 125 ? 22.087  -12.061 -114.626 1.00 91.40  ? 125 GLN B OE1 1 
ATOM 4175 N NE2 . GLN B 2 125 ? 24.246  -11.907 -115.190 1.00 90.54  ? 125 GLN B NE2 1 
ATOM 4176 N N   . ASN B 2 126 ? 20.290  -9.056  -119.478 1.00 88.62  ? 126 ASN B N   1 
ATOM 4177 C CA  . ASN B 2 126 ? 19.372  -9.284  -120.582 1.00 85.36  ? 126 ASN B CA  1 
ATOM 4178 C C   . ASN B 2 126 ? 19.703  -10.610 -121.248 1.00 85.04  ? 126 ASN B C   1 
ATOM 4179 O O   . ASN B 2 126 ? 20.858  -10.858 -121.607 1.00 87.17  ? 126 ASN B O   1 
ATOM 4180 C CB  . ASN B 2 126 ? 19.455  -8.148  -121.595 1.00 81.61  ? 126 ASN B CB  1 
ATOM 4181 C CG  . ASN B 2 126 ? 19.433  -6.796  -120.938 1.00 83.96  ? 126 ASN B CG  1 
ATOM 4182 O OD1 . ASN B 2 126 ? 20.358  -6.432  -120.218 1.00 87.50  ? 126 ASN B OD1 1 
ATOM 4183 N ND2 . ASN B 2 126 ? 18.373  -6.038  -121.178 1.00 84.52  ? 126 ASN B ND2 1 
ATOM 4184 N N   . SER B 2 127 ? 18.692  -11.454 -121.413 1.00 69.35  ? 127 SER B N   1 
ATOM 4185 C CA  . SER B 2 127 ? 18.899  -12.763 -122.002 1.00 68.40  ? 127 SER B CA  1 
ATOM 4186 C C   . SER B 2 127 ? 19.175  -12.646 -123.496 1.00 69.86  ? 127 SER B C   1 
ATOM 4187 O O   . SER B 2 127 ? 18.857  -11.644 -124.139 1.00 73.54  ? 127 SER B O   1 
ATOM 4188 C CB  . SER B 2 127 ? 17.678  -13.644 -121.774 1.00 72.19  ? 127 SER B CB  1 
ATOM 4189 O OG  . SER B 2 127 ? 16.495  -12.928 -122.066 1.00 76.23  ? 127 SER B OG  1 
ATOM 4190 N N   . LYS B 2 128 ? 19.778  -13.692 -124.046 1.00 68.56  ? 128 LYS B N   1 
ATOM 4191 C CA  . LYS B 2 128 ? 20.073  -13.776 -125.468 1.00 65.85  ? 128 LYS B CA  1 
ATOM 4192 C C   . LYS B 2 128 ? 19.102  -14.746 -126.124 1.00 70.03  ? 128 LYS B C   1 
ATOM 4193 O O   . LYS B 2 128 ? 18.910  -15.862 -125.635 1.00 78.37  ? 128 LYS B O   1 
ATOM 4194 C CB  . LYS B 2 128 ? 21.512  -14.227 -125.696 1.00 63.21  ? 128 LYS B CB  1 
ATOM 4195 C CG  . LYS B 2 128 ? 22.532  -13.299 -125.085 1.00 70.33  ? 128 LYS B CG  1 
ATOM 4196 C CD  . LYS B 2 128 ? 23.924  -13.592 -125.596 1.00 69.74  ? 128 LYS B CD  1 
ATOM 4197 C CE  . LYS B 2 128 ? 24.960  -12.829 -124.800 1.00 70.07  ? 128 LYS B CE  1 
ATOM 4198 N NZ  . LYS B 2 128 ? 24.343  -11.709 -124.048 1.00 71.40  ? 128 LYS B NZ  1 
ATOM 4199 N N   . THR B 2 129 ? 18.500  -14.322 -127.229 1.00 67.60  ? 129 THR B N   1 
ATOM 4200 C CA  . THR B 2 129 ? 17.435  -15.067 -127.891 1.00 63.90  ? 129 THR B CA  1 
ATOM 4201 C C   . THR B 2 129 ? 17.964  -15.676 -129.181 1.00 69.49  ? 129 THR B C   1 
ATOM 4202 O O   . THR B 2 129 ? 18.147  -14.967 -130.174 1.00 76.14  ? 129 THR B O   1 
ATOM 4203 C CB  . THR B 2 129 ? 16.252  -14.156 -128.183 1.00 67.93  ? 129 THR B CB  1 
ATOM 4204 O OG1 . THR B 2 129 ? 15.857  -13.488 -126.981 1.00 76.71  ? 129 THR B OG1 1 
ATOM 4205 C CG2 . THR B 2 129 ? 15.087  -14.959 -128.725 1.00 64.01  ? 129 THR B CG2 1 
ATOM 4206 N N   . TRP B 2 130 ? 18.188  -16.983 -129.176 1.00 65.81  ? 130 TRP B N   1 
ATOM 4207 C CA  . TRP B 2 130 ? 18.561  -17.696 -130.385 1.00 63.43  ? 130 TRP B CA  1 
ATOM 4208 C C   . TRP B 2 130 ? 17.302  -18.149 -131.103 1.00 62.35  ? 130 TRP B C   1 
ATOM 4209 O O   . TRP B 2 130 ? 16.312  -18.513 -130.465 1.00 77.23  ? 130 TRP B O   1 
ATOM 4210 C CB  . TRP B 2 130 ? 19.441  -18.899 -130.058 1.00 61.78  ? 130 TRP B CB  1 
ATOM 4211 C CG  . TRP B 2 130 ? 20.729  -18.523 -129.426 1.00 61.94  ? 130 TRP B CG  1 
ATOM 4212 C CD1 . TRP B 2 130 ? 20.938  -18.222 -128.120 1.00 60.55  ? 130 TRP B CD1 1 
ATOM 4213 C CD2 . TRP B 2 130 ? 21.995  -18.395 -130.076 1.00 64.47  ? 130 TRP B CD2 1 
ATOM 4214 N NE1 . TRP B 2 130 ? 22.256  -17.918 -127.911 1.00 68.48  ? 130 TRP B NE1 1 
ATOM 4215 C CE2 . TRP B 2 130 ? 22.925  -18.016 -129.100 1.00 66.18  ? 130 TRP B CE2 1 
ATOM 4216 C CE3 . TRP B 2 130 ? 22.430  -18.567 -131.390 1.00 66.86  ? 130 TRP B CE3 1 
ATOM 4217 C CZ2 . TRP B 2 130 ? 24.262  -17.806 -129.393 1.00 64.74  ? 130 TRP B CZ2 1 
ATOM 4218 C CZ3 . TRP B 2 130 ? 23.754  -18.357 -131.677 1.00 66.36  ? 130 TRP B CZ3 1 
ATOM 4219 C CH2 . TRP B 2 130 ? 24.656  -17.982 -130.684 1.00 66.43  ? 130 TRP B CH2 1 
ATOM 4220 N N   . ILE B 2 131 ? 17.336  -18.119 -132.429 1.00 56.92  ? 131 ILE B N   1 
ATOM 4221 C CA  . ILE B 2 131 ? 16.193  -18.502 -133.244 1.00 62.69  ? 131 ILE B CA  1 
ATOM 4222 C C   . ILE B 2 131 ? 16.620  -19.637 -134.161 1.00 68.27  ? 131 ILE B C   1 
ATOM 4223 O O   . ILE B 2 131 ? 17.620  -19.520 -134.876 1.00 75.76  ? 131 ILE B O   1 
ATOM 4224 C CB  . ILE B 2 131 ? 15.654  -17.317 -134.060 1.00 70.37  ? 131 ILE B CB  1 
ATOM 4225 C CG1 . ILE B 2 131 ? 14.740  -16.455 -133.202 1.00 69.64  ? 131 ILE B CG1 1 
ATOM 4226 C CG2 . ILE B 2 131 ? 14.867  -17.810 -135.245 1.00 72.59  ? 131 ILE B CG2 1 
ATOM 4227 C CD1 . ILE B 2 131 ? 14.475  -15.098 -133.790 1.00 66.29  ? 131 ILE B CD1 1 
ATOM 4228 N N   . PHE B 2 132 ? 15.861  -20.724 -134.144 1.00 64.78  ? 132 PHE B N   1 
ATOM 4229 C CA  . PHE B 2 132 ? 16.120  -21.879 -134.984 1.00 62.26  ? 132 PHE B CA  1 
ATOM 4230 C C   . PHE B 2 132 ? 14.968  -22.073 -135.955 1.00 63.17  ? 132 PHE B C   1 
ATOM 4231 O O   . PHE B 2 132 ? 13.822  -21.732 -135.657 1.00 72.84  ? 132 PHE B O   1 
ATOM 4232 C CB  . PHE B 2 132 ? 16.288  -23.147 -134.153 1.00 64.37  ? 132 PHE B CB  1 
ATOM 4233 C CG  . PHE B 2 132 ? 17.530  -23.174 -133.327 1.00 67.03  ? 132 PHE B CG  1 
ATOM 4234 C CD1 . PHE B 2 132 ? 18.715  -23.627 -133.855 1.00 64.44  ? 132 PHE B CD1 1 
ATOM 4235 C CD2 . PHE B 2 132 ? 17.512  -22.752 -132.017 1.00 70.68  ? 132 PHE B CD2 1 
ATOM 4236 C CE1 . PHE B 2 132 ? 19.853  -23.658 -133.094 1.00 63.06  ? 132 PHE B CE1 1 
ATOM 4237 C CE2 . PHE B 2 132 ? 18.650  -22.780 -131.256 1.00 65.60  ? 132 PHE B CE2 1 
ATOM 4238 C CZ  . PHE B 2 132 ? 19.820  -23.232 -131.796 1.00 62.18  ? 132 PHE B CZ  1 
ATOM 4239 N N   . GLY B 2 133 ? 15.282  -22.622 -137.126 1.00 65.44  ? 133 GLY B N   1 
ATOM 4240 C CA  . GLY B 2 133 ? 14.276  -23.030 -138.076 1.00 65.85  ? 133 GLY B CA  1 
ATOM 4241 C C   . GLY B 2 133 ? 13.955  -24.509 -137.934 1.00 77.02  ? 133 GLY B C   1 
ATOM 4242 O O   . GLY B 2 133 ? 14.510  -25.219 -137.102 1.00 79.91  ? 133 GLY B O   1 
ATOM 4243 N N   . CYS B 2 134 ? 13.031  -24.967 -138.773 1.00 84.89  ? 134 CYS B N   1 
ATOM 4244 C CA  . CYS B 2 134 ? 12.674  -26.375 -138.817 1.00 80.80  ? 134 CYS B CA  1 
ATOM 4245 C C   . CYS B 2 134 ? 12.217  -26.715 -140.222 1.00 80.85  ? 134 CYS B C   1 
ATOM 4246 O O   . CYS B 2 134 ? 11.793  -25.843 -140.980 1.00 84.06  ? 134 CYS B O   1 
ATOM 4247 C CB  . CYS B 2 134 ? 11.569  -26.715 -137.819 1.00 81.17  ? 134 CYS B CB  1 
ATOM 4248 S SG  . CYS B 2 134 ? 12.109  -26.836 -136.117 1.00 106.13 ? 134 CYS B SG  1 
ATOM 4249 N N   . GLU B 2 135 ? 12.304  -27.993 -140.567 1.00 86.48  ? 135 GLU B N   1 
ATOM 4250 C CA  . GLU B 2 135 ? 11.712  -28.414 -141.827 1.00 86.71  ? 135 GLU B CA  1 
ATOM 4251 C C   . GLU B 2 135 ? 10.259  -28.814 -141.653 1.00 88.43  ? 135 GLU B C   1 
ATOM 4252 O O   . GLU B 2 135 ? 9.426   -28.515 -142.514 1.00 92.37  ? 135 GLU B O   1 
ATOM 4253 C CB  . GLU B 2 135 ? 12.485  -29.581 -142.434 1.00 85.97  ? 135 GLU B CB  1 
ATOM 4254 C CG  . GLU B 2 135 ? 11.957  -29.975 -143.796 1.00 87.66  ? 135 GLU B CG  1 
ATOM 4255 C CD  . GLU B 2 135 ? 12.575  -31.246 -144.323 1.00 94.76  ? 135 GLU B CD  1 
ATOM 4256 O OE1 . GLU B 2 135 ? 13.344  -31.888 -143.580 1.00 99.32  ? 135 GLU B OE1 1 
ATOM 4257 O OE2 . GLU B 2 135 ? 12.291  -31.601 -145.485 1.00 96.62  ? 135 GLU B OE2 1 
ATOM 4258 N N   . LYS B 2 136 ? 9.937   -29.482 -140.549 1.00 82.09  ? 136 LYS B N   1 
ATOM 4259 C CA  . LYS B 2 136 ? 8.576   -29.949 -140.314 1.00 82.09  ? 136 LYS B CA  1 
ATOM 4260 C C   . LYS B 2 136 ? 8.425   -30.107 -138.805 1.00 77.26  ? 136 LYS B C   1 
ATOM 4261 O O   . LYS B 2 136 ? 8.934   -31.067 -138.222 1.00 84.62  ? 136 LYS B O   1 
ATOM 4262 C CB  . LYS B 2 136 ? 8.326   -31.242 -141.082 1.00 84.02  ? 136 LYS B CB  1 
ATOM 4263 C CG  . LYS B 2 136 ? 7.442   -32.292 -140.450 1.00 84.58  ? 136 LYS B CG  1 
ATOM 4264 C CD  . LYS B 2 136 ? 6.991   -33.256 -141.530 1.00 86.29  ? 136 LYS B CD  1 
ATOM 4265 C CE  . LYS B 2 136 ? 6.082   -34.330 -140.990 1.00 88.36  ? 136 LYS B CE  1 
ATOM 4266 N NZ  . LYS B 2 136 ? 4.826   -33.748 -140.449 1.00 87.87  ? 136 LYS B NZ  1 
ATOM 4267 N N   . LEU B 2 137 ? 7.768   -29.139 -138.177 1.00 71.41  ? 137 LEU B N   1 
ATOM 4268 C CA  . LEU B 2 137 ? 7.613   -29.146 -136.729 1.00 73.92  ? 137 LEU B CA  1 
ATOM 4269 C C   . LEU B 2 137 ? 6.571   -30.176 -136.326 1.00 77.59  ? 137 LEU B C   1 
ATOM 4270 O O   . LEU B 2 137 ? 5.383   -29.861 -136.220 1.00 78.49  ? 137 LEU B O   1 
ATOM 4271 C CB  . LEU B 2 137 ? 7.219   -27.759 -136.227 1.00 69.24  ? 137 LEU B CB  1 
ATOM 4272 C CG  . LEU B 2 137 ? 7.450   -27.466 -134.749 1.00 69.46  ? 137 LEU B CG  1 
ATOM 4273 C CD1 . LEU B 2 137 ? 8.923   -27.299 -134.479 1.00 76.58  ? 137 LEU B CD1 1 
ATOM 4274 C CD2 . LEU B 2 137 ? 6.720   -26.212 -134.357 1.00 71.16  ? 137 LEU B CD2 1 
ATOM 4275 N N   . ASP B 2 138 ? 7.009   -31.407 -136.099 1.00 87.77  ? 138 ASP B N   1 
ATOM 4276 C CA  . ASP B 2 138 ? 6.106   -32.521 -135.849 1.00 87.53  ? 138 ASP B CA  1 
ATOM 4277 C C   . ASP B 2 138 ? 5.546   -32.432 -134.440 1.00 88.44  ? 138 ASP B C   1 
ATOM 4278 O O   . ASP B 2 138 ? 6.301   -32.449 -133.467 1.00 93.31  ? 138 ASP B O   1 
ATOM 4279 C CB  . ASP B 2 138 ? 6.838   -33.841 -136.049 1.00 90.11  ? 138 ASP B CB  1 
ATOM 4280 C CG  . ASP B 2 138 ? 6.313   -34.608 -137.222 1.00 95.06  ? 138 ASP B CG  1 
ATOM 4281 O OD1 . ASP B 2 138 ? 5.561   -34.009 -138.013 1.00 95.70  ? 138 ASP B OD1 1 
ATOM 4282 O OD2 . ASP B 2 138 ? 6.644   -35.803 -137.352 1.00 97.89  ? 138 ASP B OD2 1 
ATOM 4283 N N   . TYR B 2 139 ? 4.224   -32.348 -134.325 1.00 76.36  ? 139 TYR B N   1 
ATOM 4284 C CA  . TYR B 2 139 ? 3.565   -32.424 -133.027 1.00 78.64  ? 139 TYR B CA  1 
ATOM 4285 C C   . TYR B 2 139 ? 3.265   -33.880 -132.711 1.00 80.86  ? 139 TYR B C   1 
ATOM 4286 O O   . TYR B 2 139 ? 2.323   -34.460 -133.258 1.00 84.65  ? 139 TYR B O   1 
ATOM 4287 C CB  . TYR B 2 139 ? 2.284   -31.595 -133.011 1.00 75.60  ? 139 TYR B CB  1 
ATOM 4288 C CG  . TYR B 2 139 ? 2.491   -30.109 -132.856 1.00 75.95  ? 139 TYR B CG  1 
ATOM 4289 C CD1 . TYR B 2 139 ? 3.420   -29.431 -133.620 1.00 79.44  ? 139 TYR B CD1 1 
ATOM 4290 C CD2 . TYR B 2 139 ? 1.748   -29.383 -131.942 1.00 77.19  ? 139 TYR B CD2 1 
ATOM 4291 C CE1 . TYR B 2 139 ? 3.604   -28.079 -133.475 1.00 83.16  ? 139 TYR B CE1 1 
ATOM 4292 C CE2 . TYR B 2 139 ? 1.928   -28.034 -131.791 1.00 76.89  ? 139 TYR B CE2 1 
ATOM 4293 C CZ  . TYR B 2 139 ? 2.857   -27.387 -132.562 1.00 80.72  ? 139 TYR B CZ  1 
ATOM 4294 O OH  . TYR B 2 139 ? 3.044   -26.036 -132.423 1.00 86.55  ? 139 TYR B OH  1 
ATOM 4295 N N   . THR B 2 140 ? 4.052   -34.471 -131.825 1.00 91.94  ? 140 THR B N   1 
ATOM 4296 C CA  . THR B 2 140 ? 3.836   -35.836 -131.382 1.00 93.37  ? 140 THR B CA  1 
ATOM 4297 C C   . THR B 2 140 ? 2.861   -35.860 -130.213 1.00 94.61  ? 140 THR B C   1 
ATOM 4298 O O   . THR B 2 140 ? 2.585   -34.838 -129.583 1.00 97.51  ? 140 THR B O   1 
ATOM 4299 C CB  . THR B 2 140 ? 5.153   -36.492 -130.973 1.00 96.37  ? 140 THR B CB  1 
ATOM 4300 O OG1 . THR B 2 140 ? 5.829   -35.655 -130.028 1.00 103.87 ? 140 THR B OG1 1 
ATOM 4301 C CG2 . THR B 2 140 ? 6.040   -36.700 -132.185 1.00 91.14  ? 140 THR B CG2 1 
ATOM 4302 N N   . SER B 2 141 ? 2.335   -37.045 -129.932 1.00 99.66  ? 141 SER B N   1 
ATOM 4303 C CA  . SER B 2 141 ? 1.381   -37.230 -128.853 1.00 101.68 ? 141 SER B CA  1 
ATOM 4304 C C   . SER B 2 141 ? 1.751   -38.458 -128.036 1.00 102.31 ? 141 SER B C   1 
ATOM 4305 O O   . SER B 2 141 ? 2.225   -39.462 -128.573 1.00 103.78 ? 141 SER B O   1 
ATOM 4306 C CB  . SER B 2 141 ? -0.039  -37.384 -129.391 1.00 103.22 ? 141 SER B CB  1 
ATOM 4307 O OG  . SER B 2 141 ? -0.071  -38.320 -130.452 1.00 105.21 ? 141 SER B OG  1 
ATOM 4308 N N   . THR B 2 142 ? 1.536   -38.361 -126.724 1.00 109.88 ? 142 THR B N   1 
ATOM 4309 C CA  . THR B 2 142 ? 1.695   -39.529 -125.866 1.00 111.87 ? 142 THR B CA  1 
ATOM 4310 C C   . THR B 2 142 ? 0.649   -40.588 -126.188 1.00 113.79 ? 142 THR B C   1 
ATOM 4311 O O   . THR B 2 142 ? 0.960   -41.784 -126.236 1.00 113.53 ? 142 THR B O   1 
ATOM 4312 C CB  . THR B 2 142 ? 1.612   -39.113 -124.398 1.00 107.54 ? 142 THR B CB  1 
ATOM 4313 O OG1 . THR B 2 142 ? 2.881   -38.599 -123.974 1.00 110.67 ? 142 THR B OG1 1 
ATOM 4314 C CG2 . THR B 2 142 ? 1.235   -40.292 -123.522 1.00 105.97 ? 142 THR B CG2 1 
ATOM 4315 N N   . ILE B 2 143 ? -0.588  -40.167 -126.431 1.00 120.90 ? 143 ILE B N   1 
ATOM 4316 C CA  . ILE B 2 143 ? -1.690  -41.077 -126.732 1.00 119.86 ? 143 ILE B CA  1 
ATOM 4317 C C   . ILE B 2 143 ? -1.402  -41.782 -128.051 1.00 121.73 ? 143 ILE B C   1 
ATOM 4318 O O   . ILE B 2 143 ? -1.140  -41.117 -129.062 1.00 121.17 ? 143 ILE B O   1 
ATOM 4319 C CB  . ILE B 2 143 ? -3.030  -40.330 -126.793 1.00 117.52 ? 143 ILE B CB  1 
ATOM 4320 C CG1 . ILE B 2 143 ? -3.250  -39.492 -125.532 1.00 118.50 ? 143 ILE B CG1 1 
ATOM 4321 C CG2 . ILE B 2 143 ? -4.173  -41.306 -126.984 1.00 116.06 ? 143 ILE B CG2 1 
ATOM 4322 C CD1 . ILE B 2 143 ? -2.943  -40.215 -124.242 1.00 118.76 ? 143 ILE B CD1 1 
ATOM 4323 N N   . PRO B 2 144 ? -1.439  -43.120 -128.094 1.00 124.31 ? 144 PRO B N   1 
ATOM 4324 C CA  . PRO B 2 144 ? -1.193  -43.852 -129.337 1.00 121.21 ? 144 PRO B CA  1 
ATOM 4325 C C   . PRO B 2 144 ? -2.452  -43.997 -130.185 1.00 117.48 ? 144 PRO B C   1 
ATOM 4326 O O   . PRO B 2 144 ? -2.451  -43.544 -131.330 1.00 114.72 ? 144 PRO B O   1 
ATOM 4327 C CB  . PRO B 2 144 ? -0.702  -45.216 -128.847 1.00 119.34 ? 144 PRO B CB  1 
ATOM 4328 C CG  . PRO B 2 144 ? -1.253  -45.364 -127.455 1.00 118.57 ? 144 PRO B CG  1 
ATOM 4329 C CD  . PRO B 2 144 ? -1.739  -44.024 -126.971 1.00 120.29 ? 144 PRO B CD  1 
# 
