data_9BVR
# 
_entry.id   9BVR 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BVR         pdb_00009bvr 10.2210/pdb9bvr/pdb 
WWPDB D_1000284134 ?            ?                   
EMDB  EMD-44942    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-01-22 ? 
2 'Structure model' 1 1 2025-03-12 ? 
3 'Structure model' 1 2 2025-03-19 ? 
4 'Structure model' 1 3 2025-03-26 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
3 3 'Structure model' 'Data collection'     
4 4 'Structure model' 'Data collection'     
5 4 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
4 3 'Structure model' em_admin        
5 4 'Structure model' citation        
6 4 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_ASTM'         
4  2 'Structure model' '_citation.journal_id_CSD'          
5  2 'Structure model' '_citation.journal_id_ISSN'         
6  2 'Structure model' '_citation.pdbx_database_id_DOI'    
7  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
8  2 'Structure model' '_citation.title'                   
9  2 'Structure model' '_citation.year'                    
10 2 'Structure model' '_em_admin.last_update'             
11 3 'Structure model' '_em_admin.last_update'             
12 4 'Structure model' '_citation.journal_volume'          
13 4 'Structure model' '_citation.page_first'              
14 4 'Structure model' '_citation.page_last'               
15 4 'Structure model' '_citation.title'                   
16 4 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BVR 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
;Vitamin K-dependent gamma-carboxylase with factor IX propeptide and partially carboxylated glutamate-rich region and with vitamin K hydroquinone and calcium
;
_pdbx_database_related.db_id          EMD-44942 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              weikai@wustl.edu 
_pdbx_contact_author.name_first         Weikai 
_pdbx_contact_author.name_last          Li 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-8711-1904 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Li, W.'  1 0000-0002-8711-1904 
'Liu, B.' 2 0000-0002-6581-780X 
'Cao, Q.' 3 0000-0003-2517-2231 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Nature 
_citation.journal_id_ASTM           NATUAS 
_citation.journal_id_CSD            0006 
_citation.journal_id_ISSN           1476-4687 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            639 
_citation.language                  ? 
_citation.page_first                816 
_citation.page_last                 824 
_citation.title                     'Molecular basis of vitamin-K-driven gamma-carboxylation at the membrane interface.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41586-025-08648-1 
_citation.pdbx_database_id_PubMed   39880037 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Cao, Q.'      1  0000-0003-2517-2231 
primary 'Ammerman, A.' 2  0000-0001-9245-4015 
primary 'Saimi, M.'    3  ?                   
primary 'Lin, Z.'      4  ?                   
primary 'Shen, G.'     5  0000-0002-5006-2790 
primary 'Chen, H.'     6  0000-0002-9835-5138 
primary 'Sun, J.'      7  0000-0001-8775-5032 
primary 'Chai, M.'     8  ?                   
primary 'Liu, S.'      9  ?                   
primary 'Hsu, F.F.'    10 ?                   
primary 'Krezel, A.M.' 11 ?                   
primary 'Gross, M.L.'  12 0000-0003-1159-4636 
primary 'Xu, J.'       13 0000-0002-2120-8287 
primary 'Garcia, B.A.' 14 0000-0003-3596-4750 
primary 'Liu, B.'      15 0000-0002-6581-780X 
primary 'Li, W.'       16 0000-0002-8711-1904 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Vitamin K-dependent gamma-carboxylase' 85005.680 1 4.1.1.90  ? ?                ? 
2 polymer     man 'Coagulation factor IX' 7802.636  1 3.4.21.22 ? 'residues 29-92' ? 
3 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   3 ?         
? ?                ? 
4 non-polymer syn 'vitamin K1 hydroquinone' 452.712   1 ?         ? ?                ? 
5 non-polymer syn 
'(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE' 763.100   2 ? 
? ?                ? 
6 non-polymer man 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208   1 ?         ? ?                ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Gamma-glutamyl carboxylase,Peptidyl-glutamate 4-carboxylase,Vitamin K gamma glutamyl carboxylase' 
2 'Christmas factor,Plasma thromboplastin component,PTC'                                             
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;GPRQDSRIGKLLGFEWTDLSSWRRLVTLLNRPTDPASLAVFRFLFGFLMVLDIPQERGLSSLDRKYLDGLDVCRFPLLDA
LRPLPLDWMYLVYTIMFLGALGMMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGLL
NAHRRNAHVPLWNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKLLLSEELTSLLVVHWGGLLLDLSA
GFLLFFDVSRSIGLFFVSYFHCMNSQLFSIGMFSYVMLASSPLFCSPEWPRKLVSYCPRRLQQLLPLKAAPQPSVSCVYK
RSRGKSGQKPGLRHQLGAAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGYL
NPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAAWSPFQRTSWVQPLL
MDLSPWRAKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGEY
HKVYTTSPSPSCYMYVYVNTTELALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQRL
QEIERRRNTPFHERFFRFLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGELNPSNTDSSHSNP
PESNPDPVHSEF
;
;GPRQDSRIGKLLGFEWTDLSSWRRLVTLLNRPTDPASLAVFRFLFGFLMVLDIPQERGLSSLDRKYLDGLDVCRFPLLDA
LRPLPLDWMYLVYTIMFLGALGMMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGLL
NAHRRNAHVPLWNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKLLLSEELTSLLVVHWGGLLLDLSA
GFLLFFDVSRSIGLFFVSYFHCMNSQLFSIGMFSYVMLASSPLFCSPEWPRKLVSYCPRRLQQLLPLKAAPQPSVSCVYK
RSRGKSGQKPGLRHQLGAAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGYL
NPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAAWSPFQRTSWVQPLL
MDLSPWRAKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGEY
HKVYTTSPSPSCYMYVYVNTTELALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQRL
QEIERRRNTPFHERFFRFLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGELNPSNTDSSHSNP
PESNPDPVHSEF
;
A ? 
2 'polypeptide(L)' no no TVFLDHENANKILNRPKRYNSGKLEEFVQGNLERECMEEKCSFEEAREVFENTERTTEFWKQYV 
TVFLDHENANKILNRPKRYNSGKLEEFVQGNLERECMEEKCSFEEAREVFENTERTTEFWKQYV P ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 'vitamin K1 hydroquinone'                                                                                            A1AVC 
5 '(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE' 6PL   
6 2-acetamido-2-deoxy-beta-D-glucopyranose                                                                             NAG   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   ARG n 
1 4   GLN n 
1 5   ASP n 
1 6   SER n 
1 7   ARG n 
1 8   ILE n 
1 9   GLY n 
1 10  LYS n 
1 11  LEU n 
1 12  LEU n 
1 13  GLY n 
1 14  PHE n 
1 15  GLU n 
1 16  TRP n 
1 17  THR n 
1 18  ASP n 
1 19  LEU n 
1 20  SER n 
1 21  SER n 
1 22  TRP n 
1 23  ARG n 
1 24  ARG n 
1 25  LEU n 
1 26  VAL n 
1 27  THR n 
1 28  LEU n 
1 29  LEU n 
1 30  ASN n 
1 31  ARG n 
1 32  PRO n 
1 33  THR n 
1 34  ASP n 
1 35  PRO n 
1 36  ALA n 
1 37  SER n 
1 38  LEU n 
1 39  ALA n 
1 40  VAL n 
1 41  PHE n 
1 42  ARG n 
1 43  PHE n 
1 44  LEU n 
1 45  PHE n 
1 46  GLY n 
1 47  PHE n 
1 48  LEU n 
1 49  MET n 
1 50  VAL n 
1 51  LEU n 
1 52  ASP n 
1 53  ILE n 
1 54  PRO n 
1 55  GLN n 
1 56  GLU n 
1 57  ARG n 
1 58  GLY n 
1 59  LEU n 
1 60  SER n 
1 61  SER n 
1 62  LEU n 
1 63  ASP n 
1 64  ARG n 
1 65  LYS n 
1 66  TYR n 
1 67  LEU n 
1 68  ASP n 
1 69  GLY n 
1 70  LEU n 
1 71  ASP n 
1 72  VAL n 
1 73  CYS n 
1 74  ARG n 
1 75  PHE n 
1 76  PRO n 
1 77  LEU n 
1 78  LEU n 
1 79  ASP n 
1 80  ALA n 
1 81  LEU n 
1 82  ARG n 
1 83  PRO n 
1 84  LEU n 
1 85  PRO n 
1 86  LEU n 
1 87  ASP n 
1 88  TRP n 
1 89  MET n 
1 90  TYR n 
1 91  LEU n 
1 92  VAL n 
1 93  TYR n 
1 94  THR n 
1 95  ILE n 
1 96  MET n 
1 97  PHE n 
1 98  LEU n 
1 99  GLY n 
1 100 ALA n 
1 101 LEU n 
1 102 GLY n 
1 103 MET n 
1 104 MET n 
1 105 LEU n 
1 106 GLY n 
1 107 LEU n 
1 108 CYS n 
1 109 TYR n 
1 110 ARG n 
1 111 ILE n 
1 112 SER n 
1 113 CYS n 
1 114 VAL n 
1 115 LEU n 
1 116 PHE n 
1 117 LEU n 
1 118 LEU n 
1 119 PRO n 
1 120 TYR n 
1 121 TRP n 
1 122 TYR n 
1 123 VAL n 
1 124 PHE n 
1 125 LEU n 
1 126 LEU n 
1 127 ASP n 
1 128 LYS n 
1 129 THR n 
1 130 SER n 
1 131 TRP n 
1 132 ASN n 
1 133 ASN n 
1 134 HIS n 
1 135 SER n 
1 136 TYR n 
1 137 LEU n 
1 138 TYR n 
1 139 GLY n 
1 140 LEU n 
1 141 LEU n 
1 142 ALA n 
1 143 PHE n 
1 144 GLN n 
1 145 LEU n 
1 146 THR n 
1 147 PHE n 
1 148 MET n 
1 149 ASP n 
1 150 ALA n 
1 151 ASN n 
1 152 HIS n 
1 153 TYR n 
1 154 TRP n 
1 155 SER n 
1 156 VAL n 
1 157 ASP n 
1 158 GLY n 
1 159 LEU n 
1 160 LEU n 
1 161 ASN n 
1 162 ALA n 
1 163 HIS n 
1 164 ARG n 
1 165 ARG n 
1 166 ASN n 
1 167 ALA n 
1 168 HIS n 
1 169 VAL n 
1 170 PRO n 
1 171 LEU n 
1 172 TRP n 
1 173 ASN n 
1 174 TYR n 
1 175 ALA n 
1 176 VAL n 
1 177 LEU n 
1 178 ARG n 
1 179 GLY n 
1 180 GLN n 
1 181 ILE n 
1 182 PHE n 
1 183 ILE n 
1 184 VAL n 
1 185 TYR n 
1 186 PHE n 
1 187 ILE n 
1 188 ALA n 
1 189 GLY n 
1 190 VAL n 
1 191 LYS n 
1 192 LYS n 
1 193 LEU n 
1 194 ASP n 
1 195 ALA n 
1 196 ASP n 
1 197 TRP n 
1 198 VAL n 
1 199 GLU n 
1 200 GLY n 
1 201 TYR n 
1 202 SER n 
1 203 MET n 
1 204 GLU n 
1 205 TYR n 
1 206 LEU n 
1 207 SER n 
1 208 ARG n 
1 209 HIS n 
1 210 TRP n 
1 211 LEU n 
1 212 PHE n 
1 213 SER n 
1 214 PRO n 
1 215 PHE n 
1 216 LYS n 
1 217 LEU n 
1 218 LEU n 
1 219 LEU n 
1 220 SER n 
1 221 GLU n 
1 222 GLU n 
1 223 LEU n 
1 224 THR n 
1 225 SER n 
1 226 LEU n 
1 227 LEU n 
1 228 VAL n 
1 229 VAL n 
1 230 HIS n 
1 231 TRP n 
1 232 GLY n 
1 233 GLY n 
1 234 LEU n 
1 235 LEU n 
1 236 LEU n 
1 237 ASP n 
1 238 LEU n 
1 239 SER n 
1 240 ALA n 
1 241 GLY n 
1 242 PHE n 
1 243 LEU n 
1 244 LEU n 
1 245 PHE n 
1 246 PHE n 
1 247 ASP n 
1 248 VAL n 
1 249 SER n 
1 250 ARG n 
1 251 SER n 
1 252 ILE n 
1 253 GLY n 
1 254 LEU n 
1 255 PHE n 
1 256 PHE n 
1 257 VAL n 
1 258 SER n 
1 259 TYR n 
1 260 PHE n 
1 261 HIS n 
1 262 CYS n 
1 263 MET n 
1 264 ASN n 
1 265 SER n 
1 266 GLN n 
1 267 LEU n 
1 268 PHE n 
1 269 SER n 
1 270 ILE n 
1 271 GLY n 
1 272 MET n 
1 273 PHE n 
1 274 SER n 
1 275 TYR n 
1 276 VAL n 
1 277 MET n 
1 278 LEU n 
1 279 ALA n 
1 280 SER n 
1 281 SER n 
1 282 PRO n 
1 283 LEU n 
1 284 PHE n 
1 285 CYS n 
1 286 SER n 
1 287 PRO n 
1 288 GLU n 
1 289 TRP n 
1 290 PRO n 
1 291 ARG n 
1 292 LYS n 
1 293 LEU n 
1 294 VAL n 
1 295 SER n 
1 296 TYR n 
1 297 CYS n 
1 298 PRO n 
1 299 ARG n 
1 300 ARG n 
1 301 LEU n 
1 302 GLN n 
1 303 GLN n 
1 304 LEU n 
1 305 LEU n 
1 306 PRO n 
1 307 LEU n 
1 308 LYS n 
1 309 ALA n 
1 310 ALA n 
1 311 PRO n 
1 312 GLN n 
1 313 PRO n 
1 314 SER n 
1 315 VAL n 
1 316 SER n 
1 317 CYS n 
1 318 VAL n 
1 319 TYR n 
1 320 LYS n 
1 321 ARG n 
1 322 SER n 
1 323 ARG n 
1 324 GLY n 
1 325 LYS n 
1 326 SER n 
1 327 GLY n 
1 328 GLN n 
1 329 LYS n 
1 330 PRO n 
1 331 GLY n 
1 332 LEU n 
1 333 ARG n 
1 334 HIS n 
1 335 GLN n 
1 336 LEU n 
1 337 GLY n 
1 338 ALA n 
1 339 ALA n 
1 340 PHE n 
1 341 THR n 
1 342 LEU n 
1 343 LEU n 
1 344 TYR n 
1 345 LEU n 
1 346 LEU n 
1 347 GLU n 
1 348 GLN n 
1 349 LEU n 
1 350 PHE n 
1 351 LEU n 
1 352 PRO n 
1 353 TYR n 
1 354 SER n 
1 355 HIS n 
1 356 PHE n 
1 357 LEU n 
1 358 THR n 
1 359 GLN n 
1 360 GLY n 
1 361 TYR n 
1 362 ASN n 
1 363 ASN n 
1 364 TRP n 
1 365 THR n 
1 366 ASN n 
1 367 GLY n 
1 368 LEU n 
1 369 TYR n 
1 370 GLY n 
1 371 TYR n 
1 372 SER n 
1 373 TRP n 
1 374 ASP n 
1 375 MET n 
1 376 MET n 
1 377 VAL n 
1 378 HIS n 
1 379 SER n 
1 380 ARG n 
1 381 SER n 
1 382 HIS n 
1 383 GLN n 
1 384 HIS n 
1 385 VAL n 
1 386 LYS n 
1 387 ILE n 
1 388 THR n 
1 389 TYR n 
1 390 ARG n 
1 391 ASP n 
1 392 GLY n 
1 393 ARG n 
1 394 THR n 
1 395 GLY n 
1 396 GLU n 
1 397 LEU n 
1 398 GLY n 
1 399 TYR n 
1 400 LEU n 
1 401 ASN n 
1 402 PRO n 
1 403 GLY n 
1 404 VAL n 
1 405 PHE n 
1 406 THR n 
1 407 GLN n 
1 408 SER n 
1 409 ARG n 
1 410 ARG n 
1 411 TRP n 
1 412 LYS n 
1 413 ASP n 
1 414 HIS n 
1 415 ALA n 
1 416 ASP n 
1 417 MET n 
1 418 LEU n 
1 419 LYS n 
1 420 GLN n 
1 421 TYR n 
1 422 ALA n 
1 423 THR n 
1 424 CYS n 
1 425 LEU n 
1 426 SER n 
1 427 ARG n 
1 428 LEU n 
1 429 LEU n 
1 430 PRO n 
1 431 LYS n 
1 432 TYR n 
1 433 ASN n 
1 434 VAL n 
1 435 THR n 
1 436 GLU n 
1 437 PRO n 
1 438 GLN n 
1 439 ILE n 
1 440 TYR n 
1 441 PHE n 
1 442 ASP n 
1 443 ILE n 
1 444 TRP n 
1 445 VAL n 
1 446 SER n 
1 447 ILE n 
1 448 ASN n 
1 449 ASP n 
1 450 ARG n 
1 451 PHE n 
1 452 GLN n 
1 453 GLN n 
1 454 ARG n 
1 455 ILE n 
1 456 PHE n 
1 457 ASP n 
1 458 PRO n 
1 459 ARG n 
1 460 VAL n 
1 461 ASP n 
1 462 ILE n 
1 463 VAL n 
1 464 GLN n 
1 465 ALA n 
1 466 ALA n 
1 467 TRP n 
1 468 SER n 
1 469 PRO n 
1 470 PHE n 
1 471 GLN n 
1 472 ARG n 
1 473 THR n 
1 474 SER n 
1 475 TRP n 
1 476 VAL n 
1 477 GLN n 
1 478 PRO n 
1 479 LEU n 
1 480 LEU n 
1 481 MET n 
1 482 ASP n 
1 483 LEU n 
1 484 SER n 
1 485 PRO n 
1 486 TRP n 
1 487 ARG n 
1 488 ALA n 
1 489 LYS n 
1 490 LEU n 
1 491 GLN n 
1 492 GLU n 
1 493 ILE n 
1 494 LYS n 
1 495 SER n 
1 496 SER n 
1 497 LEU n 
1 498 ASP n 
1 499 ASN n 
1 500 HIS n 
1 501 THR n 
1 502 GLU n 
1 503 VAL n 
1 504 VAL n 
1 505 PHE n 
1 506 ILE n 
1 507 ALA n 
1 508 ASP n 
1 509 PHE n 
1 510 PRO n 
1 511 GLY n 
1 512 LEU n 
1 513 HIS n 
1 514 LEU n 
1 515 GLU n 
1 516 ASN n 
1 517 PHE n 
1 518 VAL n 
1 519 SER n 
1 520 GLU n 
1 521 ASP n 
1 522 LEU n 
1 523 GLY n 
1 524 ASN n 
1 525 THR n 
1 526 SER n 
1 527 ILE n 
1 528 GLN n 
1 529 LEU n 
1 530 LEU n 
1 531 GLN n 
1 532 GLY n 
1 533 GLU n 
1 534 VAL n 
1 535 THR n 
1 536 VAL n 
1 537 GLU n 
1 538 LEU n 
1 539 VAL n 
1 540 ALA n 
1 541 GLU n 
1 542 GLN n 
1 543 LYS n 
1 544 ASN n 
1 545 GLN n 
1 546 THR n 
1 547 LEU n 
1 548 ARG n 
1 549 GLU n 
1 550 GLY n 
1 551 GLU n 
1 552 LYS n 
1 553 MET n 
1 554 GLN n 
1 555 LEU n 
1 556 PRO n 
1 557 ALA n 
1 558 GLY n 
1 559 GLU n 
1 560 TYR n 
1 561 HIS n 
1 562 LYS n 
1 563 VAL n 
1 564 TYR n 
1 565 THR n 
1 566 THR n 
1 567 SER n 
1 568 PRO n 
1 569 SER n 
1 570 PRO n 
1 571 SER n 
1 572 CYS n 
1 573 TYR n 
1 574 MET n 
1 575 TYR n 
1 576 VAL n 
1 577 TYR n 
1 578 VAL n 
1 579 ASN n 
1 580 THR n 
1 581 THR n 
1 582 GLU n 
1 583 LEU n 
1 584 ALA n 
1 585 LEU n 
1 586 GLU n 
1 587 GLN n 
1 588 ASP n 
1 589 LEU n 
1 590 ALA n 
1 591 TYR n 
1 592 LEU n 
1 593 GLN n 
1 594 GLU n 
1 595 LEU n 
1 596 LYS n 
1 597 GLU n 
1 598 LYS n 
1 599 VAL n 
1 600 GLU n 
1 601 ASN n 
1 602 GLY n 
1 603 SER n 
1 604 GLU n 
1 605 THR n 
1 606 GLY n 
1 607 PRO n 
1 608 LEU n 
1 609 PRO n 
1 610 PRO n 
1 611 GLU n 
1 612 LEU n 
1 613 GLN n 
1 614 PRO n 
1 615 LEU n 
1 616 LEU n 
1 617 GLU n 
1 618 GLY n 
1 619 GLU n 
1 620 VAL n 
1 621 LYS n 
1 622 GLY n 
1 623 GLY n 
1 624 PRO n 
1 625 GLU n 
1 626 PRO n 
1 627 THR n 
1 628 PRO n 
1 629 LEU n 
1 630 VAL n 
1 631 GLN n 
1 632 THR n 
1 633 PHE n 
1 634 LEU n 
1 635 ARG n 
1 636 ARG n 
1 637 GLN n 
1 638 GLN n 
1 639 ARG n 
1 640 LEU n 
1 641 GLN n 
1 642 GLU n 
1 643 ILE n 
1 644 GLU n 
1 645 ARG n 
1 646 ARG n 
1 647 ARG n 
1 648 ASN n 
1 649 THR n 
1 650 PRO n 
1 651 PHE n 
1 652 HIS n 
1 653 GLU n 
1 654 ARG n 
1 655 PHE n 
1 656 PHE n 
1 657 ARG n 
1 658 PHE n 
1 659 LEU n 
1 660 LEU n 
1 661 ARG n 
1 662 LYS n 
1 663 LEU n 
1 664 TYR n 
1 665 VAL n 
1 666 PHE n 
1 667 ARG n 
1 668 ARG n 
1 669 SER n 
1 670 PHE n 
1 671 LEU n 
1 672 MET n 
1 673 THR n 
1 674 CYS n 
1 675 ILE n 
1 676 SER n 
1 677 LEU n 
1 678 ARG n 
1 679 ASN n 
1 680 LEU n 
1 681 ILE n 
1 682 LEU n 
1 683 GLY n 
1 684 ARG n 
1 685 PRO n 
1 686 SER n 
1 687 LEU n 
1 688 GLU n 
1 689 GLN n 
1 690 LEU n 
1 691 ALA n 
1 692 GLN n 
1 693 GLU n 
1 694 VAL n 
1 695 THR n 
1 696 TYR n 
1 697 ALA n 
1 698 ASN n 
1 699 LEU n 
1 700 ARG n 
1 701 PRO n 
1 702 PHE n 
1 703 GLU n 
1 704 ALA n 
1 705 VAL n 
1 706 GLY n 
1 707 GLU n 
1 708 LEU n 
1 709 ASN n 
1 710 PRO n 
1 711 SER n 
1 712 ASN n 
1 713 THR n 
1 714 ASP n 
1 715 SER n 
1 716 SER n 
1 717 HIS n 
1 718 SER n 
1 719 ASN n 
1 720 PRO n 
1 721 PRO n 
1 722 GLU n 
1 723 SER n 
1 724 ASN n 
1 725 PRO n 
1 726 ASP n 
1 727 PRO n 
1 728 VAL n 
1 729 HIS n 
1 730 SER n 
1 731 GLU n 
1 732 PHE n 
2 1   THR n 
2 2   VAL n 
2 3   PHE n 
2 4   LEU n 
2 5   ASP n 
2 6   HIS n 
2 7   GLU n 
2 8   ASN n 
2 9   ALA n 
2 10  ASN n 
2 11  LYS n 
2 12  ILE n 
2 13  LEU n 
2 14  ASN n 
2 15  ARG n 
2 16  PRO n 
2 17  LYS n 
2 18  ARG n 
2 19  TYR n 
2 20  ASN n 
2 21  SER n 
2 22  GLY n 
2 23  LYS n 
2 24  LEU n 
2 25  GLU n 
2 26  GLU n 
2 27  PHE n 
2 28  VAL n 
2 29  GLN n 
2 30  GLY n 
2 31  ASN n 
2 32  LEU n 
2 33  GLU n 
2 34  ARG n 
2 35  GLU n 
2 36  CYS n 
2 37  MET n 
2 38  GLU n 
2 39  GLU n 
2 40  LYS n 
2 41  CYS n 
2 42  SER n 
2 43  PHE n 
2 44  GLU n 
2 45  GLU n 
2 46  ALA n 
2 47  ARG n 
2 48  GLU n 
2 49  VAL n 
2 50  PHE n 
2 51  GLU n 
2 52  ASN n 
2 53  THR n 
2 54  GLU n 
2 55  ARG n 
2 56  THR n 
2 57  THR n 
2 58  GLU n 
2 59  PHE n 
2 60  TRP n 
2 61  LYS n 
2 62  GLN n 
2 63  TYR n 
2 64  VAL n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 732 human ? 'GGCX, GC' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? 
? ? ? ? ? ? HEK293S ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 64  human ? F9         ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? 
? ? ? ? ? ? HEK293S ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   3 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 3 DGlcpNAcb1-4DGlcpNAcb1-ROH                            'Glycam Condensed Sequence' GMML       1.0   
2 3 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1' WURCS                       PDB2Glycan 1.1.0 
3 3 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}'       LINUCS                      PDB-CARE   ?     
# 
_pdbx_entity_branch_link.link_id                    1 
_pdbx_entity_branch_link.entity_id                  3 
_pdbx_entity_branch_link.entity_branch_list_num_1   2 
_pdbx_entity_branch_link.comp_id_1                  NAG 
_pdbx_entity_branch_link.atom_id_1                  C1 
_pdbx_entity_branch_link.leaving_atom_id_1          O1 
_pdbx_entity_branch_link.entity_branch_list_num_2   1 
_pdbx_entity_branch_link.comp_id_2                  NAG 
_pdbx_entity_branch_link.atom_id_2                  O4 
_pdbx_entity_branch_link.leaving_atom_id_2          HO4 
_pdbx_entity_branch_link.value_order                sing 
_pdbx_entity_branch_link.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
6PL   non-polymer                  . 
'(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE' 
1-PALMITOYL-2-STEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE 'C42 H85 N O8 P 1' 763.100 
A1AVC non-polymer                  . 'vitamin K1 hydroquinone' 
'2-methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]naphthalene-1,4-diol' 'C31 H48 O2'       452.712 
ALA   'L-peptide linking'          y ALANINE ? 'C3 H7 N O2'       89.093  
ARG   'L-peptide linking'          y ARGININE ? 'C6 H15 N4 O2 1'   175.209 
ASN   'L-peptide linking'          y ASPARAGINE ? 'C4 H8 N2 O3'      132.118 
ASP   'L-peptide linking'          y 'ASPARTIC ACID' ? 'C4 H7 N O4'       133.103 
CYS   'L-peptide linking'          y CYSTEINE ? 'C3 H7 N O2 S'     121.158 
GLN   'L-peptide linking'          y GLUTAMINE ? 'C5 H10 N2 O3'     146.144 
GLU   'L-peptide linking'          y 'GLUTAMIC ACID' ? 'C5 H9 N O4'       147.129 
GLY   'peptide linking'            y GLYCINE ? 'C2 H5 N O2'       75.067  
HIS   'L-peptide linking'          y HISTIDINE ? 'C6 H10 N3 O2 1'   156.162 
ILE   'L-peptide linking'          y ISOLEUCINE ? 'C6 H13 N O2'      131.173 
LEU   'L-peptide linking'          y LEUCINE ? 'C6 H13 N O2'      131.173 
LYS   'L-peptide linking'          y LYSINE ? 'C6 H15 N2 O2 1'   147.195 
MET   'L-peptide linking'          y METHIONINE ? 'C5 H11 N O2 S'    149.211 
NAG   'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'      221.208 
PHE   'L-peptide linking'          y PHENYLALANINE ? 'C9 H11 N O2'      165.189 
PRO   'L-peptide linking'          y PROLINE ? 'C5 H9 N O2'       115.130 
SER   'L-peptide linking'          y SERINE ? 'C3 H7 N O3'       105.093 
THR   'L-peptide linking'          y THREONINE ? 'C4 H9 N O3'       119.119 
TRP   'L-peptide linking'          y TRYPTOPHAN ? 'C11 H12 N2 O2'    204.225 
TYR   'L-peptide linking'          y TYROSINE ? 'C9 H11 N O3'      181.189 
VAL   'L-peptide linking'          y VALINE ? 'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   27  ?   ?   ?   A . n 
A 1 2   PRO 2   28  ?   ?   ?   A . n 
A 1 3   ARG 3   29  ?   ?   ?   A . n 
A 1 4   GLN 4   30  ?   ?   ?   A . n 
A 1 5   ASP 5   31  31  ASP ASP A . n 
A 1 6   SER 6   32  32  SER SER A . n 
A 1 7   ARG 7   33  33  ARG ARG A . n 
A 1 8   ILE 8   34  34  ILE ILE A . n 
A 1 9   GLY 9   35  35  GLY GLY A . n 
A 1 10  LYS 10  36  36  LYS LYS A . n 
A 1 11  LEU 11  37  37  LEU LEU A . n 
A 1 12  LEU 12  38  38  LEU LEU A . n 
A 1 13  GLY 13  39  39  GLY GLY A . n 
A 1 14  PHE 14  40  40  PHE PHE A . n 
A 1 15  GLU 15  41  41  GLU GLU A . n 
A 1 16  TRP 16  42  42  TRP TRP A . n 
A 1 17  THR 17  43  43  THR THR A . n 
A 1 18  ASP 18  44  44  ASP ASP A . n 
A 1 19  LEU 19  45  45  LEU LEU A . n 
A 1 20  SER 20  46  46  SER SER A . n 
A 1 21  SER 21  47  47  SER SER A . n 
A 1 22  TRP 22  48  48  TRP TRP A . n 
A 1 23  ARG 23  49  49  ARG ARG A . n 
A 1 24  ARG 24  50  50  ARG ARG A . n 
A 1 25  LEU 25  51  51  LEU LEU A . n 
A 1 26  VAL 26  52  52  VAL VAL A . n 
A 1 27  THR 27  53  53  THR THR A . n 
A 1 28  LEU 28  54  54  LEU LEU A . n 
A 1 29  LEU 29  55  55  LEU LEU A . n 
A 1 30  ASN 30  56  56  ASN ASN A . n 
A 1 31  ARG 31  57  57  ARG ARG A . n 
A 1 32  PRO 32  58  58  PRO PRO A . n 
A 1 33  THR 33  59  59  THR THR A . n 
A 1 34  ASP 34  60  60  ASP ASP A . n 
A 1 35  PRO 35  61  61  PRO PRO A . n 
A 1 36  ALA 36  62  62  ALA ALA A . n 
A 1 37  SER 37  63  63  SER SER A . n 
A 1 38  LEU 38  64  64  LEU LEU A . n 
A 1 39  ALA 39  65  65  ALA ALA A . n 
A 1 40  VAL 40  66  66  VAL VAL A . n 
A 1 41  PHE 41  67  67  PHE PHE A . n 
A 1 42  ARG 42  68  68  ARG ARG A . n 
A 1 43  PHE 43  69  69  PHE PHE A . n 
A 1 44  LEU 44  70  70  LEU LEU A . n 
A 1 45  PHE 45  71  71  PHE PHE A . n 
A 1 46  GLY 46  72  72  GLY GLY A . n 
A 1 47  PHE 47  73  73  PHE PHE A . n 
A 1 48  LEU 48  74  74  LEU LEU A . n 
A 1 49  MET 49  75  75  MET MET A . n 
A 1 50  VAL 50  76  76  VAL VAL A . n 
A 1 51  LEU 51  77  77  LEU LEU A . n 
A 1 52  ASP 52  78  78  ASP ASP A . n 
A 1 53  ILE 53  79  79  ILE ILE A . n 
A 1 54  PRO 54  80  80  PRO PRO A . n 
A 1 55  GLN 55  81  81  GLN GLN A . n 
A 1 56  GLU 56  82  82  GLU GLU A . n 
A 1 57  ARG 57  83  83  ARG ARG A . n 
A 1 58  GLY 58  84  84  GLY GLY A . n 
A 1 59  LEU 59  85  85  LEU LEU A . n 
A 1 60  SER 60  86  86  SER SER A . n 
A 1 61  SER 61  87  87  SER SER A . n 
A 1 62  LEU 62  88  88  LEU LEU A . n 
A 1 63  ASP 63  89  89  ASP ASP A . n 
A 1 64  ARG 64  90  90  ARG ARG A . n 
A 1 65  LYS 65  91  91  LYS LYS A . n 
A 1 66  TYR 66  92  92  TYR TYR A . n 
A 1 67  LEU 67  93  93  LEU LEU A . n 
A 1 68  ASP 68  94  94  ASP ASP A . n 
A 1 69  GLY 69  95  95  GLY GLY A . n 
A 1 70  LEU 70  96  96  LEU LEU A . n 
A 1 71  ASP 71  97  97  ASP ASP A . n 
A 1 72  VAL 72  98  98  VAL VAL A . n 
A 1 73  CYS 73  99  99  CYS CYS A . n 
A 1 74  ARG 74  100 100 ARG ARG A . n 
A 1 75  PHE 75  101 101 PHE PHE A . n 
A 1 76  PRO 76  102 102 PRO PRO A . n 
A 1 77  LEU 77  103 103 LEU LEU A . n 
A 1 78  LEU 78  104 104 LEU LEU A . n 
A 1 79  ASP 79  105 105 ASP ASP A . n 
A 1 80  ALA 80  106 106 ALA ALA A . n 
A 1 81  LEU 81  107 107 LEU LEU A . n 
A 1 82  ARG 82  108 108 ARG ARG A . n 
A 1 83  PRO 83  109 109 PRO PRO A . n 
A 1 84  LEU 84  110 110 LEU LEU A . n 
A 1 85  PRO 85  111 111 PRO PRO A . n 
A 1 86  LEU 86  112 112 LEU LEU A . n 
A 1 87  ASP 87  113 113 ASP ASP A . n 
A 1 88  TRP 88  114 114 TRP TRP A . n 
A 1 89  MET 89  115 115 MET MET A . n 
A 1 90  TYR 90  116 116 TYR TYR A . n 
A 1 91  LEU 91  117 117 LEU LEU A . n 
A 1 92  VAL 92  118 118 VAL VAL A . n 
A 1 93  TYR 93  119 119 TYR TYR A . n 
A 1 94  THR 94  120 120 THR THR A . n 
A 1 95  ILE 95  121 121 ILE ILE A . n 
A 1 96  MET 96  122 122 MET MET A . n 
A 1 97  PHE 97  123 123 PHE PHE A . n 
A 1 98  LEU 98  124 124 LEU LEU A . n 
A 1 99  GLY 99  125 125 GLY GLY A . n 
A 1 100 ALA 100 126 126 ALA ALA A . n 
A 1 101 LEU 101 127 127 LEU LEU A . n 
A 1 102 GLY 102 128 128 GLY GLY A . n 
A 1 103 MET 103 129 129 MET MET A . n 
A 1 104 MET 104 130 130 MET MET A . n 
A 1 105 LEU 105 131 131 LEU LEU A . n 
A 1 106 GLY 106 132 132 GLY GLY A . n 
A 1 107 LEU 107 133 133 LEU LEU A . n 
A 1 108 CYS 108 134 134 CYS CYS A . n 
A 1 109 TYR 109 135 135 TYR TYR A . n 
A 1 110 ARG 110 136 136 ARG ARG A . n 
A 1 111 ILE 111 137 137 ILE ILE A . n 
A 1 112 SER 112 138 138 SER SER A . n 
A 1 113 CYS 113 139 139 CYS CYS A . n 
A 1 114 VAL 114 140 140 VAL VAL A . n 
A 1 115 LEU 115 141 141 LEU LEU A . n 
A 1 116 PHE 116 142 142 PHE PHE A . n 
A 1 117 LEU 117 143 143 LEU LEU A . n 
A 1 118 LEU 118 144 144 LEU LEU A . n 
A 1 119 PRO 119 145 145 PRO PRO A . n 
A 1 120 TYR 120 146 146 TYR TYR A . n 
A 1 121 TRP 121 147 147 TRP TRP A . n 
A 1 122 TYR 122 148 148 TYR TYR A . n 
A 1 123 VAL 123 149 149 VAL VAL A . n 
A 1 124 PHE 124 150 150 PHE PHE A . n 
A 1 125 LEU 125 151 151 LEU LEU A . n 
A 1 126 LEU 126 152 152 LEU LEU A . n 
A 1 127 ASP 127 153 153 ASP ASP A . n 
A 1 128 LYS 128 154 154 LYS LYS A . n 
A 1 129 THR 129 155 155 THR THR A . n 
A 1 130 SER 130 156 156 SER SER A . n 
A 1 131 TRP 131 157 157 TRP TRP A . n 
A 1 132 ASN 132 158 158 ASN ASN A . n 
A 1 133 ASN 133 159 159 ASN ASN A . n 
A 1 134 HIS 134 160 160 HIS HIS A . n 
A 1 135 SER 135 161 161 SER SER A . n 
A 1 136 TYR 136 162 162 TYR TYR A . n 
A 1 137 LEU 137 163 163 LEU LEU A . n 
A 1 138 TYR 138 164 164 TYR TYR A . n 
A 1 139 GLY 139 165 165 GLY GLY A . n 
A 1 140 LEU 140 166 166 LEU LEU A . n 
A 1 141 LEU 141 167 167 LEU LEU A . n 
A 1 142 ALA 142 168 168 ALA ALA A . n 
A 1 143 PHE 143 169 169 PHE PHE A . n 
A 1 144 GLN 144 170 170 GLN GLN A . n 
A 1 145 LEU 145 171 171 LEU LEU A . n 
A 1 146 THR 146 172 172 THR THR A . n 
A 1 147 PHE 147 173 173 PHE PHE A . n 
A 1 148 MET 148 174 174 MET MET A . n 
A 1 149 ASP 149 175 175 ASP ASP A . n 
A 1 150 ALA 150 176 176 ALA ALA A . n 
A 1 151 ASN 151 177 177 ASN ASN A . n 
A 1 152 HIS 152 178 178 HIS HIS A . n 
A 1 153 TYR 153 179 179 TYR TYR A . n 
A 1 154 TRP 154 180 180 TRP TRP A . n 
A 1 155 SER 155 181 181 SER SER A . n 
A 1 156 VAL 156 182 182 VAL VAL A . n 
A 1 157 ASP 157 183 183 ASP ASP A . n 
A 1 158 GLY 158 184 184 GLY GLY A . n 
A 1 159 LEU 159 185 185 LEU LEU A . n 
A 1 160 LEU 160 186 186 LEU LEU A . n 
A 1 161 ASN 161 187 187 ASN ASN A . n 
A 1 162 ALA 162 188 188 ALA ALA A . n 
A 1 163 HIS 163 189 189 HIS HIS A . n 
A 1 164 ARG 164 190 190 ARG ARG A . n 
A 1 165 ARG 165 191 191 ARG ARG A . n 
A 1 166 ASN 166 192 192 ASN ASN A . n 
A 1 167 ALA 167 193 193 ALA ALA A . n 
A 1 168 HIS 168 194 194 HIS HIS A . n 
A 1 169 VAL 169 195 195 VAL VAL A . n 
A 1 170 PRO 170 196 196 PRO PRO A . n 
A 1 171 LEU 171 197 197 LEU LEU A . n 
A 1 172 TRP 172 198 198 TRP TRP A . n 
A 1 173 ASN 173 199 199 ASN ASN A . n 
A 1 174 TYR 174 200 200 TYR TYR A . n 
A 1 175 ALA 175 201 201 ALA ALA A . n 
A 1 176 VAL 176 202 202 VAL VAL A . n 
A 1 177 LEU 177 203 203 LEU LEU A . n 
A 1 178 ARG 178 204 204 ARG ARG A . n 
A 1 179 GLY 179 205 205 GLY GLY A . n 
A 1 180 GLN 180 206 206 GLN GLN A . n 
A 1 181 ILE 181 207 207 ILE ILE A . n 
A 1 182 PHE 182 208 208 PHE PHE A . n 
A 1 183 ILE 183 209 209 ILE ILE A . n 
A 1 184 VAL 184 210 210 VAL VAL A . n 
A 1 185 TYR 185 211 211 TYR TYR A . n 
A 1 186 PHE 186 212 212 PHE PHE A . n 
A 1 187 ILE 187 213 213 ILE ILE A . n 
A 1 188 ALA 188 214 214 ALA ALA A . n 
A 1 189 GLY 189 215 215 GLY GLY A . n 
A 1 190 VAL 190 216 216 VAL VAL A . n 
A 1 191 LYS 191 217 217 LYS LYS A . n 
A 1 192 LYS 192 218 218 LYS LYS A . n 
A 1 193 LEU 193 219 219 LEU LEU A . n 
A 1 194 ASP 194 220 220 ASP ASP A . n 
A 1 195 ALA 195 221 221 ALA ALA A . n 
A 1 196 ASP 196 222 222 ASP ASP A . n 
A 1 197 TRP 197 223 223 TRP TRP A . n 
A 1 198 VAL 198 224 224 VAL VAL A . n 
A 1 199 GLU 199 225 225 GLU GLU A . n 
A 1 200 GLY 200 226 226 GLY GLY A . n 
A 1 201 TYR 201 227 227 TYR TYR A . n 
A 1 202 SER 202 228 228 SER SER A . n 
A 1 203 MET 203 229 229 MET MET A . n 
A 1 204 GLU 204 230 230 GLU GLU A . n 
A 1 205 TYR 205 231 231 TYR TYR A . n 
A 1 206 LEU 206 232 232 LEU LEU A . n 
A 1 207 SER 207 233 233 SER SER A . n 
A 1 208 ARG 208 234 234 ARG ARG A . n 
A 1 209 HIS 209 235 235 HIS HIS A . n 
A 1 210 TRP 210 236 236 TRP TRP A . n 
A 1 211 LEU 211 237 237 LEU LEU A . n 
A 1 212 PHE 212 238 238 PHE PHE A . n 
A 1 213 SER 213 239 239 SER SER A . n 
A 1 214 PRO 214 240 240 PRO PRO A . n 
A 1 215 PHE 215 241 241 PHE PHE A . n 
A 1 216 LYS 216 242 242 LYS LYS A . n 
A 1 217 LEU 217 243 243 LEU LEU A . n 
A 1 218 LEU 218 244 244 LEU LEU A . n 
A 1 219 LEU 219 245 245 LEU LEU A . n 
A 1 220 SER 220 246 246 SER SER A . n 
A 1 221 GLU 221 247 247 GLU GLU A . n 
A 1 222 GLU 222 248 248 GLU GLU A . n 
A 1 223 LEU 223 249 249 LEU LEU A . n 
A 1 224 THR 224 250 250 THR THR A . n 
A 1 225 SER 225 251 251 SER SER A . n 
A 1 226 LEU 226 252 252 LEU LEU A . n 
A 1 227 LEU 227 253 253 LEU LEU A . n 
A 1 228 VAL 228 254 254 VAL VAL A . n 
A 1 229 VAL 229 255 255 VAL VAL A . n 
A 1 230 HIS 230 256 256 HIS HIS A . n 
A 1 231 TRP 231 257 257 TRP TRP A . n 
A 1 232 GLY 232 258 258 GLY GLY A . n 
A 1 233 GLY 233 259 259 GLY GLY A . n 
A 1 234 LEU 234 260 260 LEU LEU A . n 
A 1 235 LEU 235 261 261 LEU LEU A . n 
A 1 236 LEU 236 262 262 LEU LEU A . n 
A 1 237 ASP 237 263 263 ASP ASP A . n 
A 1 238 LEU 238 264 264 LEU LEU A . n 
A 1 239 SER 239 265 265 SER SER A . n 
A 1 240 ALA 240 266 266 ALA ALA A . n 
A 1 241 GLY 241 267 267 GLY GLY A . n 
A 1 242 PHE 242 268 268 PHE PHE A . n 
A 1 243 LEU 243 269 269 LEU LEU A . n 
A 1 244 LEU 244 270 270 LEU LEU A . n 
A 1 245 PHE 245 271 271 PHE PHE A . n 
A 1 246 PHE 246 272 272 PHE PHE A . n 
A 1 247 ASP 247 273 273 ASP ASP A . n 
A 1 248 VAL 248 274 274 VAL VAL A . n 
A 1 249 SER 249 275 275 SER SER A . n 
A 1 250 ARG 250 276 276 ARG ARG A . n 
A 1 251 SER 251 277 277 SER SER A . n 
A 1 252 ILE 252 278 278 ILE ILE A . n 
A 1 253 GLY 253 279 279 GLY GLY A . n 
A 1 254 LEU 254 280 280 LEU LEU A . n 
A 1 255 PHE 255 281 281 PHE PHE A . n 
A 1 256 PHE 256 282 282 PHE PHE A . n 
A 1 257 VAL 257 283 283 VAL VAL A . n 
A 1 258 SER 258 284 284 SER SER A . n 
A 1 259 TYR 259 285 285 TYR TYR A . n 
A 1 260 PHE 260 286 286 PHE PHE A . n 
A 1 261 HIS 261 287 287 HIS HIS A . n 
A 1 262 CYS 262 288 288 CYS CYS A . n 
A 1 263 MET 263 289 289 MET MET A . n 
A 1 264 ASN 264 290 290 ASN ASN A . n 
A 1 265 SER 265 291 291 SER SER A . n 
A 1 266 GLN 266 292 292 GLN GLN A . n 
A 1 267 LEU 267 293 293 LEU LEU A . n 
A 1 268 PHE 268 294 294 PHE PHE A . n 
A 1 269 SER 269 295 295 SER SER A . n 
A 1 270 ILE 270 296 296 ILE ILE A . n 
A 1 271 GLY 271 297 297 GLY GLY A . n 
A 1 272 MET 272 298 298 MET MET A . n 
A 1 273 PHE 273 299 299 PHE PHE A . n 
A 1 274 SER 274 300 300 SER SER A . n 
A 1 275 TYR 275 301 301 TYR TYR A . n 
A 1 276 VAL 276 302 302 VAL VAL A . n 
A 1 277 MET 277 303 303 MET MET A . n 
A 1 278 LEU 278 304 304 LEU LEU A . n 
A 1 279 ALA 279 305 305 ALA ALA A . n 
A 1 280 SER 280 306 306 SER SER A . n 
A 1 281 SER 281 307 307 SER SER A . n 
A 1 282 PRO 282 308 308 PRO PRO A . n 
A 1 283 LEU 283 309 309 LEU LEU A . n 
A 1 284 PHE 284 310 310 PHE PHE A . n 
A 1 285 CYS 285 311 311 CYS CYS A . n 
A 1 286 SER 286 312 312 SER SER A . n 
A 1 287 PRO 287 313 313 PRO PRO A . n 
A 1 288 GLU 288 314 314 GLU GLU A . n 
A 1 289 TRP 289 315 315 TRP TRP A . n 
A 1 290 PRO 290 316 316 PRO PRO A . n 
A 1 291 ARG 291 317 317 ARG ARG A . n 
A 1 292 LYS 292 318 318 LYS LYS A . n 
A 1 293 LEU 293 319 319 LEU LEU A . n 
A 1 294 VAL 294 320 320 VAL VAL A . n 
A 1 295 SER 295 321 321 SER SER A . n 
A 1 296 TYR 296 322 322 TYR TYR A . n 
A 1 297 CYS 297 323 323 CYS CYS A . n 
A 1 298 PRO 298 324 324 PRO PRO A . n 
A 1 299 ARG 299 325 325 ARG ARG A . n 
A 1 300 ARG 300 326 326 ARG ARG A . n 
A 1 301 LEU 301 327 327 LEU LEU A . n 
A 1 302 GLN 302 328 328 GLN GLN A . n 
A 1 303 GLN 303 329 329 GLN GLN A . n 
A 1 304 LEU 304 330 330 LEU LEU A . n 
A 1 305 LEU 305 331 331 LEU LEU A . n 
A 1 306 PRO 306 332 332 PRO PRO A . n 
A 1 307 LEU 307 333 333 LEU LEU A . n 
A 1 308 LYS 308 334 334 LYS LYS A . n 
A 1 309 ALA 309 335 335 ALA ALA A . n 
A 1 310 ALA 310 336 336 ALA ALA A . n 
A 1 311 PRO 311 337 337 PRO PRO A . n 
A 1 312 GLN 312 338 338 GLN GLN A . n 
A 1 313 PRO 313 339 339 PRO PRO A . n 
A 1 314 SER 314 340 340 SER SER A . n 
A 1 315 VAL 315 341 341 VAL VAL A . n 
A 1 316 SER 316 342 342 SER SER A . n 
A 1 317 CYS 317 343 343 CYS CYS A . n 
A 1 318 VAL 318 344 344 VAL VAL A . n 
A 1 319 TYR 319 345 345 TYR TYR A . n 
A 1 320 LYS 320 346 346 LYS LYS A . n 
A 1 321 ARG 321 347 347 ARG ARG A . n 
A 1 322 SER 322 348 ?   ?   ?   A . n 
A 1 323 ARG 323 349 ?   ?   ?   A . n 
A 1 324 GLY 324 350 ?   ?   ?   A . n 
A 1 325 LYS 325 351 ?   ?   ?   A . n 
A 1 326 SER 326 352 ?   ?   ?   A . n 
A 1 327 GLY 327 353 353 GLY GLY A . n 
A 1 328 GLN 328 354 354 GLN GLN A . n 
A 1 329 LYS 329 355 355 LYS LYS A . n 
A 1 330 PRO 330 356 356 PRO PRO A . n 
A 1 331 GLY 331 357 357 GLY GLY A . n 
A 1 332 LEU 332 358 358 LEU LEU A . n 
A 1 333 ARG 333 359 359 ARG ARG A . n 
A 1 334 HIS 334 360 360 HIS HIS A . n 
A 1 335 GLN 335 361 361 GLN GLN A . n 
A 1 336 LEU 336 362 362 LEU LEU A . n 
A 1 337 GLY 337 363 363 GLY GLY A . n 
A 1 338 ALA 338 364 364 ALA ALA A . n 
A 1 339 ALA 339 365 365 ALA ALA A . n 
A 1 340 PHE 340 366 366 PHE PHE A . n 
A 1 341 THR 341 367 367 THR THR A . n 
A 1 342 LEU 342 368 368 LEU LEU A . n 
A 1 343 LEU 343 369 369 LEU LEU A . n 
A 1 344 TYR 344 370 370 TYR TYR A . n 
A 1 345 LEU 345 371 371 LEU LEU A . n 
A 1 346 LEU 346 372 372 LEU LEU A . n 
A 1 347 GLU 347 373 373 GLU GLU A . n 
A 1 348 GLN 348 374 374 GLN GLN A . n 
A 1 349 LEU 349 375 375 LEU LEU A . n 
A 1 350 PHE 350 376 376 PHE PHE A . n 
A 1 351 LEU 351 377 377 LEU LEU A . n 
A 1 352 PRO 352 378 378 PRO PRO A . n 
A 1 353 TYR 353 379 379 TYR TYR A . n 
A 1 354 SER 354 380 380 SER SER A . n 
A 1 355 HIS 355 381 381 HIS HIS A . n 
A 1 356 PHE 356 382 382 PHE PHE A . n 
A 1 357 LEU 357 383 383 LEU LEU A . n 
A 1 358 THR 358 384 384 THR THR A . n 
A 1 359 GLN 359 385 385 GLN GLN A . n 
A 1 360 GLY 360 386 386 GLY GLY A . n 
A 1 361 TYR 361 387 387 TYR TYR A . n 
A 1 362 ASN 362 388 388 ASN ASN A . n 
A 1 363 ASN 363 389 389 ASN ASN A . n 
A 1 364 TRP 364 390 390 TRP TRP A . n 
A 1 365 THR 365 391 391 THR THR A . n 
A 1 366 ASN 366 392 392 ASN ASN A . n 
A 1 367 GLY 367 393 393 GLY GLY A . n 
A 1 368 LEU 368 394 394 LEU LEU A . n 
A 1 369 TYR 369 395 395 TYR TYR A . n 
A 1 370 GLY 370 396 396 GLY GLY A . n 
A 1 371 TYR 371 397 397 TYR TYR A . n 
A 1 372 SER 372 398 398 SER SER A . n 
A 1 373 TRP 373 399 399 TRP TRP A . n 
A 1 374 ASP 374 400 400 ASP ASP A . n 
A 1 375 MET 375 401 401 MET MET A . n 
A 1 376 MET 376 402 402 MET MET A . n 
A 1 377 VAL 377 403 403 VAL VAL A . n 
A 1 378 HIS 378 404 404 HIS HIS A . n 
A 1 379 SER 379 405 405 SER SER A . n 
A 1 380 ARG 380 406 406 ARG ARG A . n 
A 1 381 SER 381 407 407 SER SER A . n 
A 1 382 HIS 382 408 408 HIS HIS A . n 
A 1 383 GLN 383 409 409 GLN GLN A . n 
A 1 384 HIS 384 410 410 HIS HIS A . n 
A 1 385 VAL 385 411 411 VAL VAL A . n 
A 1 386 LYS 386 412 412 LYS LYS A . n 
A 1 387 ILE 387 413 413 ILE ILE A . n 
A 1 388 THR 388 414 414 THR THR A . n 
A 1 389 TYR 389 415 415 TYR TYR A . n 
A 1 390 ARG 390 416 416 ARG ARG A . n 
A 1 391 ASP 391 417 417 ASP ASP A . n 
A 1 392 GLY 392 418 418 GLY GLY A . n 
A 1 393 ARG 393 419 419 ARG ARG A . n 
A 1 394 THR 394 420 420 THR THR A . n 
A 1 395 GLY 395 421 421 GLY GLY A . n 
A 1 396 GLU 396 422 422 GLU GLU A . n 
A 1 397 LEU 397 423 423 LEU LEU A . n 
A 1 398 GLY 398 424 424 GLY GLY A . n 
A 1 399 TYR 399 425 425 TYR TYR A . n 
A 1 400 LEU 400 426 426 LEU LEU A . n 
A 1 401 ASN 401 427 427 ASN ASN A . n 
A 1 402 PRO 402 428 428 PRO PRO A . n 
A 1 403 GLY 403 429 429 GLY GLY A . n 
A 1 404 VAL 404 430 430 VAL VAL A . n 
A 1 405 PHE 405 431 431 PHE PHE A . n 
A 1 406 THR 406 432 432 THR THR A . n 
A 1 407 GLN 407 433 433 GLN GLN A . n 
A 1 408 SER 408 434 434 SER SER A . n 
A 1 409 ARG 409 435 435 ARG ARG A . n 
A 1 410 ARG 410 436 436 ARG ARG A . n 
A 1 411 TRP 411 437 437 TRP TRP A . n 
A 1 412 LYS 412 438 438 LYS LYS A . n 
A 1 413 ASP 413 439 439 ASP ASP A . n 
A 1 414 HIS 414 440 440 HIS HIS A . n 
A 1 415 ALA 415 441 441 ALA ALA A . n 
A 1 416 ASP 416 442 442 ASP ASP A . n 
A 1 417 MET 417 443 443 MET MET A . n 
A 1 418 LEU 418 444 444 LEU LEU A . n 
A 1 419 LYS 419 445 445 LYS LYS A . n 
A 1 420 GLN 420 446 446 GLN GLN A . n 
A 1 421 TYR 421 447 447 TYR TYR A . n 
A 1 422 ALA 422 448 448 ALA ALA A . n 
A 1 423 THR 423 449 449 THR THR A . n 
A 1 424 CYS 424 450 450 CYS CYS A . n 
A 1 425 LEU 425 451 451 LEU LEU A . n 
A 1 426 SER 426 452 452 SER SER A . n 
A 1 427 ARG 427 453 453 ARG ARG A . n 
A 1 428 LEU 428 454 454 LEU LEU A . n 
A 1 429 LEU 429 455 455 LEU LEU A . n 
A 1 430 PRO 430 456 456 PRO PRO A . n 
A 1 431 LYS 431 457 457 LYS LYS A . n 
A 1 432 TYR 432 458 458 TYR TYR A . n 
A 1 433 ASN 433 459 459 ASN ASN A . n 
A 1 434 VAL 434 460 460 VAL VAL A . n 
A 1 435 THR 435 461 461 THR THR A . n 
A 1 436 GLU 436 462 462 GLU GLU A . n 
A 1 437 PRO 437 463 463 PRO PRO A . n 
A 1 438 GLN 438 464 464 GLN GLN A . n 
A 1 439 ILE 439 465 465 ILE ILE A . n 
A 1 440 TYR 440 466 466 TYR TYR A . n 
A 1 441 PHE 441 467 467 PHE PHE A . n 
A 1 442 ASP 442 468 468 ASP ASP A . n 
A 1 443 ILE 443 469 469 ILE ILE A . n 
A 1 444 TRP 444 470 470 TRP TRP A . n 
A 1 445 VAL 445 471 471 VAL VAL A . n 
A 1 446 SER 446 472 472 SER SER A . n 
A 1 447 ILE 447 473 473 ILE ILE A . n 
A 1 448 ASN 448 474 474 ASN ASN A . n 
A 1 449 ASP 449 475 475 ASP ASP A . n 
A 1 450 ARG 450 476 476 ARG ARG A . n 
A 1 451 PHE 451 477 477 PHE PHE A . n 
A 1 452 GLN 452 478 478 GLN GLN A . n 
A 1 453 GLN 453 479 479 GLN GLN A . n 
A 1 454 ARG 454 480 480 ARG ARG A . n 
A 1 455 ILE 455 481 481 ILE ILE A . n 
A 1 456 PHE 456 482 482 PHE PHE A . n 
A 1 457 ASP 457 483 483 ASP ASP A . n 
A 1 458 PRO 458 484 484 PRO PRO A . n 
A 1 459 ARG 459 485 485 ARG ARG A . n 
A 1 460 VAL 460 486 486 VAL VAL A . n 
A 1 461 ASP 461 487 487 ASP ASP A . n 
A 1 462 ILE 462 488 488 ILE ILE A . n 
A 1 463 VAL 463 489 489 VAL VAL A . n 
A 1 464 GLN 464 490 490 GLN GLN A . n 
A 1 465 ALA 465 491 491 ALA ALA A . n 
A 1 466 ALA 466 492 492 ALA ALA A . n 
A 1 467 TRP 467 493 493 TRP TRP A . n 
A 1 468 SER 468 494 494 SER SER A . n 
A 1 469 PRO 469 495 495 PRO PRO A . n 
A 1 470 PHE 470 496 496 PHE PHE A . n 
A 1 471 GLN 471 497 497 GLN GLN A . n 
A 1 472 ARG 472 498 498 ARG ARG A . n 
A 1 473 THR 473 499 499 THR THR A . n 
A 1 474 SER 474 500 500 SER SER A . n 
A 1 475 TRP 475 501 501 TRP TRP A . n 
A 1 476 VAL 476 502 502 VAL VAL A . n 
A 1 477 GLN 477 503 503 GLN GLN A . n 
A 1 478 PRO 478 504 504 PRO PRO A . n 
A 1 479 LEU 479 505 505 LEU LEU A . n 
A 1 480 LEU 480 506 506 LEU LEU A . n 
A 1 481 MET 481 507 507 MET MET A . n 
A 1 482 ASP 482 508 508 ASP ASP A . n 
A 1 483 LEU 483 509 509 LEU LEU A . n 
A 1 484 SER 484 510 510 SER SER A . n 
A 1 485 PRO 485 511 511 PRO PRO A . n 
A 1 486 TRP 486 512 512 TRP TRP A . n 
A 1 487 ARG 487 513 513 ARG ARG A . n 
A 1 488 ALA 488 514 514 ALA ALA A . n 
A 1 489 LYS 489 515 515 LYS LYS A . n 
A 1 490 LEU 490 516 516 LEU LEU A . n 
A 1 491 GLN 491 517 517 GLN GLN A . n 
A 1 492 GLU 492 518 518 GLU GLU A . n 
A 1 493 ILE 493 519 519 ILE ILE A . n 
A 1 494 LYS 494 520 520 LYS LYS A . n 
A 1 495 SER 495 521 521 SER SER A . n 
A 1 496 SER 496 522 522 SER SER A . n 
A 1 497 LEU 497 523 523 LEU LEU A . n 
A 1 498 ASP 498 524 524 ASP ASP A . n 
A 1 499 ASN 499 525 525 ASN ASN A . n 
A 1 500 HIS 500 526 526 HIS HIS A . n 
A 1 501 THR 501 527 527 THR THR A . n 
A 1 502 GLU 502 528 528 GLU GLU A . n 
A 1 503 VAL 503 529 529 VAL VAL A . n 
A 1 504 VAL 504 530 530 VAL VAL A . n 
A 1 505 PHE 505 531 531 PHE PHE A . n 
A 1 506 ILE 506 532 532 ILE ILE A . n 
A 1 507 ALA 507 533 533 ALA ALA A . n 
A 1 508 ASP 508 534 534 ASP ASP A . n 
A 1 509 PHE 509 535 535 PHE PHE A . n 
A 1 510 PRO 510 536 536 PRO PRO A . n 
A 1 511 GLY 511 537 537 GLY GLY A . n 
A 1 512 LEU 512 538 538 LEU LEU A . n 
A 1 513 HIS 513 539 539 HIS HIS A . n 
A 1 514 LEU 514 540 540 LEU LEU A . n 
A 1 515 GLU 515 541 541 GLU GLU A . n 
A 1 516 ASN 516 542 542 ASN ASN A . n 
A 1 517 PHE 517 543 543 PHE PHE A . n 
A 1 518 VAL 518 544 544 VAL VAL A . n 
A 1 519 SER 519 545 545 SER SER A . n 
A 1 520 GLU 520 546 546 GLU GLU A . n 
A 1 521 ASP 521 547 547 ASP ASP A . n 
A 1 522 LEU 522 548 548 LEU LEU A . n 
A 1 523 GLY 523 549 549 GLY GLY A . n 
A 1 524 ASN 524 550 550 ASN ASN A . n 
A 1 525 THR 525 551 551 THR THR A . n 
A 1 526 SER 526 552 552 SER SER A . n 
A 1 527 ILE 527 553 553 ILE ILE A . n 
A 1 528 GLN 528 554 554 GLN GLN A . n 
A 1 529 LEU 529 555 555 LEU LEU A . n 
A 1 530 LEU 530 556 556 LEU LEU A . n 
A 1 531 GLN 531 557 557 GLN GLN A . n 
A 1 532 GLY 532 558 558 GLY GLY A . n 
A 1 533 GLU 533 559 559 GLU GLU A . n 
A 1 534 VAL 534 560 560 VAL VAL A . n 
A 1 535 THR 535 561 561 THR THR A . n 
A 1 536 VAL 536 562 562 VAL VAL A . n 
A 1 537 GLU 537 563 563 GLU GLU A . n 
A 1 538 LEU 538 564 564 LEU LEU A . n 
A 1 539 VAL 539 565 565 VAL VAL A . n 
A 1 540 ALA 540 566 566 ALA ALA A . n 
A 1 541 GLU 541 567 567 GLU GLU A . n 
A 1 542 GLN 542 568 568 GLN GLN A . n 
A 1 543 LYS 543 569 569 LYS LYS A . n 
A 1 544 ASN 544 570 570 ASN ASN A . n 
A 1 545 GLN 545 571 571 GLN GLN A . n 
A 1 546 THR 546 572 572 THR THR A . n 
A 1 547 LEU 547 573 573 LEU LEU A . n 
A 1 548 ARG 548 574 574 ARG ARG A . n 
A 1 549 GLU 549 575 575 GLU GLU A . n 
A 1 550 GLY 550 576 576 GLY GLY A . n 
A 1 551 GLU 551 577 577 GLU GLU A . n 
A 1 552 LYS 552 578 578 LYS LYS A . n 
A 1 553 MET 553 579 579 MET MET A . n 
A 1 554 GLN 554 580 580 GLN GLN A . n 
A 1 555 LEU 555 581 581 LEU LEU A . n 
A 1 556 PRO 556 582 582 PRO PRO A . n 
A 1 557 ALA 557 583 583 ALA ALA A . n 
A 1 558 GLY 558 584 584 GLY GLY A . n 
A 1 559 GLU 559 585 585 GLU GLU A . n 
A 1 560 TYR 560 586 586 TYR TYR A . n 
A 1 561 HIS 561 587 587 HIS HIS A . n 
A 1 562 LYS 562 588 588 LYS LYS A . n 
A 1 563 VAL 563 589 589 VAL VAL A . n 
A 1 564 TYR 564 590 590 TYR TYR A . n 
A 1 565 THR 565 591 591 THR THR A . n 
A 1 566 THR 566 592 592 THR THR A . n 
A 1 567 SER 567 593 593 SER SER A . n 
A 1 568 PRO 568 594 594 PRO PRO A . n 
A 1 569 SER 569 595 595 SER SER A . n 
A 1 570 PRO 570 596 596 PRO PRO A . n 
A 1 571 SER 571 597 597 SER SER A . n 
A 1 572 CYS 572 598 598 CYS CYS A . n 
A 1 573 TYR 573 599 599 TYR TYR A . n 
A 1 574 MET 574 600 600 MET MET A . n 
A 1 575 TYR 575 601 601 TYR TYR A . n 
A 1 576 VAL 576 602 602 VAL VAL A . n 
A 1 577 TYR 577 603 603 TYR TYR A . n 
A 1 578 VAL 578 604 604 VAL VAL A . n 
A 1 579 ASN 579 605 605 ASN ASN A . n 
A 1 580 THR 580 606 606 THR THR A . n 
A 1 581 THR 581 607 607 THR THR A . n 
A 1 582 GLU 582 608 608 GLU GLU A . n 
A 1 583 LEU 583 609 609 LEU LEU A . n 
A 1 584 ALA 584 610 610 ALA ALA A . n 
A 1 585 LEU 585 611 611 LEU LEU A . n 
A 1 586 GLU 586 612 612 GLU GLU A . n 
A 1 587 GLN 587 613 613 GLN GLN A . n 
A 1 588 ASP 588 614 614 ASP ASP A . n 
A 1 589 LEU 589 615 615 LEU LEU A . n 
A 1 590 ALA 590 616 616 ALA ALA A . n 
A 1 591 TYR 591 617 617 TYR TYR A . n 
A 1 592 LEU 592 618 618 LEU LEU A . n 
A 1 593 GLN 593 619 619 GLN GLN A . n 
A 1 594 GLU 594 620 620 GLU GLU A . n 
A 1 595 LEU 595 621 621 LEU LEU A . n 
A 1 596 LYS 596 622 622 LYS LYS A . n 
A 1 597 GLU 597 623 623 GLU GLU A . n 
A 1 598 LYS 598 624 624 LYS LYS A . n 
A 1 599 VAL 599 625 625 VAL VAL A . n 
A 1 600 GLU 600 626 626 GLU GLU A . n 
A 1 601 ASN 601 627 627 ASN ASN A . n 
A 1 602 GLY 602 628 628 GLY GLY A . n 
A 1 603 SER 603 629 629 SER SER A . n 
A 1 604 GLU 604 630 630 GLU GLU A . n 
A 1 605 THR 605 631 631 THR THR A . n 
A 1 606 GLY 606 632 632 GLY GLY A . n 
A 1 607 PRO 607 633 633 PRO PRO A . n 
A 1 608 LEU 608 634 634 LEU LEU A . n 
A 1 609 PRO 609 635 635 PRO PRO A . n 
A 1 610 PRO 610 636 636 PRO PRO A . n 
A 1 611 GLU 611 637 637 GLU GLU A . n 
A 1 612 LEU 612 638 638 LEU LEU A . n 
A 1 613 GLN 613 639 639 GLN GLN A . n 
A 1 614 PRO 614 640 640 PRO PRO A . n 
A 1 615 LEU 615 641 641 LEU LEU A . n 
A 1 616 LEU 616 642 642 LEU LEU A . n 
A 1 617 GLU 617 643 643 GLU GLU A . n 
A 1 618 GLY 618 644 644 GLY GLY A . n 
A 1 619 GLU 619 645 645 GLU GLU A . n 
A 1 620 VAL 620 646 646 VAL VAL A . n 
A 1 621 LYS 621 647 647 LYS LYS A . n 
A 1 622 GLY 622 648 648 GLY GLY A . n 
A 1 623 GLY 623 649 649 GLY GLY A . n 
A 1 624 PRO 624 650 650 PRO PRO A . n 
A 1 625 GLU 625 651 651 GLU GLU A . n 
A 1 626 PRO 626 652 652 PRO PRO A . n 
A 1 627 THR 627 653 653 THR THR A . n 
A 1 628 PRO 628 654 654 PRO PRO A . n 
A 1 629 LEU 629 655 655 LEU LEU A . n 
A 1 630 VAL 630 656 656 VAL VAL A . n 
A 1 631 GLN 631 657 657 GLN GLN A . n 
A 1 632 THR 632 658 658 THR THR A . n 
A 1 633 PHE 633 659 659 PHE PHE A . n 
A 1 634 LEU 634 660 660 LEU LEU A . n 
A 1 635 ARG 635 661 661 ARG ARG A . n 
A 1 636 ARG 636 662 662 ARG ARG A . n 
A 1 637 GLN 637 663 663 GLN GLN A . n 
A 1 638 GLN 638 664 664 GLN GLN A . n 
A 1 639 ARG 639 665 665 ARG ARG A . n 
A 1 640 LEU 640 666 666 LEU LEU A . n 
A 1 641 GLN 641 667 667 GLN GLN A . n 
A 1 642 GLU 642 668 668 GLU GLU A . n 
A 1 643 ILE 643 669 669 ILE ILE A . n 
A 1 644 GLU 644 670 670 GLU GLU A . n 
A 1 645 ARG 645 671 671 ARG ARG A . n 
A 1 646 ARG 646 672 672 ARG ARG A . n 
A 1 647 ARG 647 673 673 ARG ARG A . n 
A 1 648 ASN 648 674 674 ASN ASN A . n 
A 1 649 THR 649 675 675 THR THR A . n 
A 1 650 PRO 650 676 676 PRO PRO A . n 
A 1 651 PHE 651 677 677 PHE PHE A . n 
A 1 652 HIS 652 678 678 HIS HIS A . n 
A 1 653 GLU 653 679 679 GLU GLU A . n 
A 1 654 ARG 654 680 680 ARG ARG A . n 
A 1 655 PHE 655 681 681 PHE PHE A . n 
A 1 656 PHE 656 682 682 PHE PHE A . n 
A 1 657 ARG 657 683 683 ARG ARG A . n 
A 1 658 PHE 658 684 684 PHE PHE A . n 
A 1 659 LEU 659 685 685 LEU LEU A . n 
A 1 660 LEU 660 686 686 LEU LEU A . n 
A 1 661 ARG 661 687 687 ARG ARG A . n 
A 1 662 LYS 662 688 688 LYS LYS A . n 
A 1 663 LEU 663 689 689 LEU LEU A . n 
A 1 664 TYR 664 690 690 TYR TYR A . n 
A 1 665 VAL 665 691 691 VAL VAL A . n 
A 1 666 PHE 666 692 692 PHE PHE A . n 
A 1 667 ARG 667 693 693 ARG ARG A . n 
A 1 668 ARG 668 694 694 ARG ARG A . n 
A 1 669 SER 669 695 695 SER SER A . n 
A 1 670 PHE 670 696 696 PHE PHE A . n 
A 1 671 LEU 671 697 697 LEU LEU A . n 
A 1 672 MET 672 698 698 MET MET A . n 
A 1 673 THR 673 699 699 THR THR A . n 
A 1 674 CYS 674 700 700 CYS CYS A . n 
A 1 675 ILE 675 701 701 ILE ILE A . n 
A 1 676 SER 676 702 702 SER SER A . n 
A 1 677 LEU 677 703 703 LEU LEU A . n 
A 1 678 ARG 678 704 704 ARG ARG A . n 
A 1 679 ASN 679 705 705 ASN ASN A . n 
A 1 680 LEU 680 706 706 LEU LEU A . n 
A 1 681 ILE 681 707 707 ILE ILE A . n 
A 1 682 LEU 682 708 708 LEU LEU A . n 
A 1 683 GLY 683 709 709 GLY GLY A . n 
A 1 684 ARG 684 710 710 ARG ARG A . n 
A 1 685 PRO 685 711 711 PRO PRO A . n 
A 1 686 SER 686 712 712 SER SER A . n 
A 1 687 LEU 687 713 713 LEU LEU A . n 
A 1 688 GLU 688 714 714 GLU GLU A . n 
A 1 689 GLN 689 715 715 GLN GLN A . n 
A 1 690 LEU 690 716 716 LEU LEU A . n 
A 1 691 ALA 691 717 717 ALA ALA A . n 
A 1 692 GLN 692 718 718 GLN GLN A . n 
A 1 693 GLU 693 719 719 GLU GLU A . n 
A 1 694 VAL 694 720 720 VAL VAL A . n 
A 1 695 THR 695 721 721 THR THR A . n 
A 1 696 TYR 696 722 722 TYR TYR A . n 
A 1 697 ALA 697 723 723 ALA ALA A . n 
A 1 698 ASN 698 724 724 ASN ASN A . n 
A 1 699 LEU 699 725 725 LEU LEU A . n 
A 1 700 ARG 700 726 726 ARG ARG A . n 
A 1 701 PRO 701 727 727 PRO PRO A . n 
A 1 702 PHE 702 728 728 PHE PHE A . n 
A 1 703 GLU 703 729 ?   ?   ?   A . n 
A 1 704 ALA 704 730 ?   ?   ?   A . n 
A 1 705 VAL 705 731 ?   ?   ?   A . n 
A 1 706 GLY 706 732 ?   ?   ?   A . n 
A 1 707 GLU 707 733 ?   ?   ?   A . n 
A 1 708 LEU 708 734 ?   ?   ?   A . n 
A 1 709 ASN 709 735 ?   ?   ?   A . n 
A 1 710 PRO 710 736 ?   ?   ?   A . n 
A 1 711 SER 711 737 ?   ?   ?   A . n 
A 1 712 ASN 712 738 ?   ?   ?   A . n 
A 1 713 THR 713 739 ?   ?   ?   A . n 
A 1 714 ASP 714 740 ?   ?   ?   A . n 
A 1 715 SER 715 741 ?   ?   ?   A . n 
A 1 716 SER 716 742 ?   ?   ?   A . n 
A 1 717 HIS 717 743 ?   ?   ?   A . n 
A 1 718 SER 718 744 ?   ?   ?   A . n 
A 1 719 ASN 719 745 ?   ?   ?   A . n 
A 1 720 PRO 720 746 ?   ?   ?   A . n 
A 1 721 PRO 721 747 ?   ?   ?   A . n 
A 1 722 GLU 722 748 ?   ?   ?   A . n 
A 1 723 SER 723 749 ?   ?   ?   A . n 
A 1 724 ASN 724 750 ?   ?   ?   A . n 
A 1 725 PRO 725 751 ?   ?   ?   A . n 
A 1 726 ASP 726 752 ?   ?   ?   A . n 
A 1 727 PRO 727 753 ?   ?   ?   A . n 
A 1 728 VAL 728 754 ?   ?   ?   A . n 
A 1 729 HIS 729 755 ?   ?   ?   A . n 
A 1 730 SER 730 756 ?   ?   ?   A . n 
A 1 731 GLU 731 757 ?   ?   ?   A . n 
A 1 732 PHE 732 758 ?   ?   ?   A . n 
B 2 1   THR 1   29  29  THR THR P . n 
B 2 2   VAL 2   30  30  VAL VAL P . n 
B 2 3   PHE 3   31  31  PHE PHE P . n 
B 2 4   LEU 4   32  32  LEU LEU P . n 
B 2 5   ASP 5   33  33  ASP ASP P . n 
B 2 6   HIS 6   34  34  HIS HIS P . n 
B 2 7   GLU 7   35  35  GLU GLU P . n 
B 2 8   ASN 8   36  36  ASN ASN P . n 
B 2 9   ALA 9   37  37  ALA ALA P . n 
B 2 10  ASN 10  38  38  ASN ASN P . n 
B 2 11  LYS 11  39  39  LYS LYS P . n 
B 2 12  ILE 12  40  40  ILE ILE P . n 
B 2 13  LEU 13  41  41  LEU LEU P . n 
B 2 14  ASN 14  42  42  ASN ASN P . n 
B 2 15  ARG 15  43  43  ARG ARG P . n 
B 2 16  PRO 16  44  44  PRO PRO P . n 
B 2 17  LYS 17  45  45  LYS LYS P . n 
B 2 18  ARG 18  46  46  ARG ARG P . n 
B 2 19  TYR 19  47  47  TYR TYR P . n 
B 2 20  ASN 20  48  48  ASN ASN P . n 
B 2 21  SER 21  49  49  SER SER P . n 
B 2 22  GLY 22  50  50  GLY GLY P . n 
B 2 23  LYS 23  51  51  LYS LYS P . n 
B 2 24  LEU 24  52  52  LEU LEU P . n 
B 2 25  GLU 25  53  53  GLU GLU P . n 
B 2 26  GLU 26  54  54  GLU GLU P . n 
B 2 27  PHE 27  55  55  PHE PHE P . n 
B 2 28  VAL 28  56  56  VAL VAL P . n 
B 2 29  GLN 29  57  57  GLN GLN P . n 
B 2 30  GLY 30  58  58  GLY GLY P . n 
B 2 31  ASN 31  59  59  ASN ASN P . n 
B 2 32  LEU 32  60  60  LEU LEU P . n 
B 2 33  GLU 33  61  61  GLU GLU P . n 
B 2 34  ARG 34  62  62  ARG ARG P . n 
B 2 35  GLU 35  63  63  GLU GLU P . n 
B 2 36  CYS 36  64  64  CYS CYS P . n 
B 2 37  MET 37  65  65  MET MET P . n 
B 2 38  GLU 38  66  66  GLU GLU P . n 
B 2 39  GLU 39  67  67  GLU GLU P . n 
B 2 40  LYS 40  68  68  LYS LYS P . n 
B 2 41  CYS 41  69  69  CYS CYS P . n 
B 2 42  SER 42  70  70  SER SER P . n 
B 2 43  PHE 43  71  71  PHE PHE P . n 
B 2 44  GLU 44  72  72  GLU GLU P . n 
B 2 45  GLU 45  73  73  GLU GLU P . n 
B 2 46  ALA 46  74  74  ALA ALA P . n 
B 2 47  ARG 47  75  75  ARG ARG P . n 
B 2 48  GLU 48  76  76  GLU GLU P . n 
B 2 49  VAL 49  77  77  VAL VAL P . n 
B 2 50  PHE 50  78  78  PHE PHE P . n 
B 2 51  GLU 51  79  79  GLU GLU P . n 
B 2 52  ASN 52  80  80  ASN ASN P . n 
B 2 53  THR 53  81  81  THR THR P . n 
B 2 54  GLU 54  82  82  GLU GLU P . n 
B 2 55  ARG 55  83  83  ARG ARG P . n 
B 2 56  THR 56  84  84  THR THR P . n 
B 2 57  THR 57  85  85  THR THR P . n 
B 2 58  GLU 58  86  86  GLU GLU P . n 
B 2 59  PHE 59  87  87  PHE PHE P . n 
B 2 60  TRP 60  88  88  TRP TRP P . n 
B 2 61  LYS 61  89  89  LYS LYS P . n 
B 2 62  GLN 62  90  ?   ?   ?   P . n 
B 2 63  TYR 63  91  ?   ?   ?   P . n 
B 2 64  VAL 64  92  ?   ?   ?   P . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
C 3 NAG 1 B NAG 1 B NAG 1 n 
C 3 NAG 2 B NAG 2 B NAG 2 n 
D 3 NAG 1 C NAG 1 C NAG 1 n 
D 3 NAG 2 C NAG 2 C NAG 2 n 
E 3 NAG 1 D NAG 1 D NAG 1 n 
E 3 NAG 2 D NAG 2 D NAG 2 n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 6PL   ? ? 6PL   ? ? 'SUBJECT OF INVESTIGATION' ? 
2 A1AVC ? ? A1AVC ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
F 4 A1AVC 1 801 801 A1AVC KH2 A . 
G 5 6PL   1 802 802 6PL   6PL A . 
H 5 6PL   1 803 803 6PL   6PL A . 
I 6 NAG   1 804 13  NAG   NAG A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 P LYS 45  ? CB  ? B LYS 17 CB  
2   1 Y 1 P LYS 45  ? CG  ? B LYS 17 CG  
3   1 Y 1 P LYS 45  ? CD  ? B LYS 17 CD  
4   1 Y 1 P LYS 45  ? CE  ? B LYS 17 CE  
5   1 Y 1 P LYS 45  ? NZ  ? B LYS 17 NZ  
6   1 Y 1 P ARG 46  ? CB  ? B ARG 18 CB  
7   1 Y 1 P ARG 46  ? CG  ? B ARG 18 CG  
8   1 Y 1 P ARG 46  ? CD  ? B ARG 18 CD  
9   1 Y 1 P ARG 46  ? NE  ? B ARG 18 NE  
10  1 Y 1 P ARG 46  ? CZ  ? B ARG 18 CZ  
11  1 Y 1 P ARG 46  ? NH1 ? B ARG 18 NH1 
12  1 Y 1 P ARG 46  ? NH2 ? B ARG 18 NH2 
13  1 Y 1 P TYR 47  ? CB  ? B TYR 19 CB  
14  1 Y 1 P TYR 47  ? CG  ? B TYR 19 CG  
15  1 Y 1 P TYR 47  ? CD1 ? B TYR 19 CD1 
16  1 Y 1 P TYR 47  ? CD2 ? B TYR 19 CD2 
17  1 Y 1 P TYR 47  ? CE1 ? B TYR 19 CE1 
18  1 Y 1 P TYR 47  ? CE2 ? B TYR 19 CE2 
19  1 Y 1 P TYR 47  ? CZ  ? B TYR 19 CZ  
20  1 Y 1 P TYR 47  ? OH  ? B TYR 19 OH  
21  1 Y 1 P ASN 48  ? CB  ? B ASN 20 CB  
22  1 Y 1 P ASN 48  ? CG  ? B ASN 20 CG  
23  1 Y 1 P ASN 48  ? OD1 ? B ASN 20 OD1 
24  1 Y 1 P ASN 48  ? ND2 ? B ASN 20 ND2 
25  1 Y 1 P SER 49  ? CB  ? B SER 21 CB  
26  1 Y 1 P SER 49  ? OG  ? B SER 21 OG  
27  1 Y 1 P LYS 51  ? CB  ? B LYS 23 CB  
28  1 Y 1 P LYS 51  ? CG  ? B LYS 23 CG  
29  1 Y 1 P LYS 51  ? CD  ? B LYS 23 CD  
30  1 Y 1 P LYS 51  ? CE  ? B LYS 23 CE  
31  1 Y 1 P LYS 51  ? NZ  ? B LYS 23 NZ  
32  1 Y 1 P LEU 52  ? CB  ? B LEU 24 CB  
33  1 Y 1 P LEU 52  ? CG  ? B LEU 24 CG  
34  1 Y 1 P LEU 52  ? CD1 ? B LEU 24 CD1 
35  1 Y 1 P LEU 52  ? CD2 ? B LEU 24 CD2 
36  1 Y 1 P GLU 53  ? CB  ? B GLU 25 CB  
37  1 Y 1 P GLU 53  ? CG  ? B GLU 25 CG  
38  1 Y 1 P GLU 53  ? CD  ? B GLU 25 CD  
39  1 Y 1 P GLU 53  ? OE1 ? B GLU 25 OE1 
40  1 Y 1 P GLU 53  ? OE2 ? B GLU 25 OE2 
41  1 Y 1 P GLU 54  ? CB  ? B GLU 26 CB  
42  1 Y 1 P GLU 54  ? CG  ? B GLU 26 CG  
43  1 Y 1 P GLU 54  ? CD  ? B GLU 26 CD  
44  1 Y 1 P GLU 54  ? OE1 ? B GLU 26 OE1 
45  1 Y 1 P GLU 54  ? OE2 ? B GLU 26 OE2 
46  1 Y 1 P PHE 55  ? CB  ? B PHE 27 CB  
47  1 Y 1 P PHE 55  ? CG  ? B PHE 27 CG  
48  1 Y 1 P PHE 55  ? CD1 ? B PHE 27 CD1 
49  1 Y 1 P PHE 55  ? CD2 ? B PHE 27 CD2 
50  1 Y 1 P PHE 55  ? CE1 ? B PHE 27 CE1 
51  1 Y 1 P PHE 55  ? CE2 ? B PHE 27 CE2 
52  1 Y 1 P PHE 55  ? CZ  ? B PHE 27 CZ  
53  1 Y 1 P VAL 56  ? CB  ? B VAL 28 CB  
54  1 Y 1 P VAL 56  ? CG1 ? B VAL 28 CG1 
55  1 Y 1 P VAL 56  ? CG2 ? B VAL 28 CG2 
56  1 Y 1 P GLN 57  ? CB  ? B GLN 29 CB  
57  1 Y 1 P GLN 57  ? CG  ? B GLN 29 CG  
58  1 Y 1 P GLN 57  ? CD  ? B GLN 29 CD  
59  1 Y 1 P GLN 57  ? OE1 ? B GLN 29 OE1 
60  1 Y 1 P GLN 57  ? NE2 ? B GLN 29 NE2 
61  1 Y 1 P ASN 59  ? CB  ? B ASN 31 CB  
62  1 Y 1 P ASN 59  ? CG  ? B ASN 31 CG  
63  1 Y 1 P ASN 59  ? OD1 ? B ASN 31 OD1 
64  1 Y 1 P ASN 59  ? ND2 ? B ASN 31 ND2 
65  1 Y 1 P LEU 60  ? CB  ? B LEU 32 CB  
66  1 Y 1 P LEU 60  ? CG  ? B LEU 32 CG  
67  1 Y 1 P LEU 60  ? CD1 ? B LEU 32 CD1 
68  1 Y 1 P LEU 60  ? CD2 ? B LEU 32 CD2 
69  1 Y 1 P GLU 61  ? CB  ? B GLU 33 CB  
70  1 Y 1 P GLU 61  ? CG  ? B GLU 33 CG  
71  1 Y 1 P GLU 61  ? CD  ? B GLU 33 CD  
72  1 Y 1 P GLU 61  ? OE1 ? B GLU 33 OE1 
73  1 Y 1 P GLU 61  ? OE2 ? B GLU 33 OE2 
74  1 Y 1 P ARG 62  ? CB  ? B ARG 34 CB  
75  1 Y 1 P ARG 62  ? CG  ? B ARG 34 CG  
76  1 Y 1 P ARG 62  ? CD  ? B ARG 34 CD  
77  1 Y 1 P ARG 62  ? NE  ? B ARG 34 NE  
78  1 Y 1 P ARG 62  ? CZ  ? B ARG 34 CZ  
79  1 Y 1 P ARG 62  ? NH1 ? B ARG 34 NH1 
80  1 Y 1 P ARG 62  ? NH2 ? B ARG 34 NH2 
81  1 Y 1 P GLU 63  ? CB  ? B GLU 35 CB  
82  1 Y 1 P GLU 63  ? CG  ? B GLU 35 CG  
83  1 Y 1 P GLU 63  ? CD  ? B GLU 35 CD  
84  1 Y 1 P GLU 63  ? OE1 ? B GLU 35 OE1 
85  1 Y 1 P GLU 63  ? OE2 ? B GLU 35 OE2 
86  1 Y 1 P CYS 64  ? CB  ? B CYS 36 CB  
87  1 Y 1 P CYS 64  ? SG  ? B CYS 36 SG  
88  1 Y 1 P MET 65  ? CB  ? B MET 37 CB  
89  1 Y 1 P MET 65  ? CG  ? B MET 37 CG  
90  1 Y 1 P MET 65  ? SD  ? B MET 37 SD  
91  1 Y 1 P MET 65  ? CE  ? B MET 37 CE  
92  1 Y 1 P GLU 66  ? CB  ? B GLU 38 CB  
93  1 Y 1 P GLU 66  ? CG  ? B GLU 38 CG  
94  1 Y 1 P GLU 66  ? CD  ? B GLU 38 CD  
95  1 Y 1 P GLU 66  ? OE1 ? B GLU 38 OE1 
96  1 Y 1 P GLU 66  ? OE2 ? B GLU 38 OE2 
97  1 Y 1 P GLU 67  ? CB  ? B GLU 39 CB  
98  1 Y 1 P GLU 67  ? CG  ? B GLU 39 CG  
99  1 Y 1 P GLU 67  ? CD  ? B GLU 39 CD  
100 1 Y 1 P GLU 67  ? OE1 ? B GLU 39 OE1 
101 1 Y 1 P GLU 67  ? OE2 ? B GLU 39 OE2 
102 1 Y 1 P LYS 68  ? CB  ? B LYS 40 CB  
103 1 Y 1 P LYS 68  ? CG  ? B LYS 40 CG  
104 1 Y 1 P LYS 68  ? CD  ? B LYS 40 CD  
105 1 Y 1 P LYS 68  ? CE  ? B LYS 40 CE  
106 1 Y 1 P LYS 68  ? NZ  ? B LYS 40 NZ  
107 1 Y 1 P CYS 69  ? CB  ? B CYS 41 CB  
108 1 Y 1 P CYS 69  ? SG  ? B CYS 41 SG  
109 1 Y 1 P SER 70  ? CB  ? B SER 42 CB  
110 1 Y 1 P SER 70  ? OG  ? B SER 42 OG  
111 1 Y 1 P PHE 71  ? CB  ? B PHE 43 CB  
112 1 Y 1 P PHE 71  ? CG  ? B PHE 43 CG  
113 1 Y 1 P PHE 71  ? CD1 ? B PHE 43 CD1 
114 1 Y 1 P PHE 71  ? CD2 ? B PHE 43 CD2 
115 1 Y 1 P PHE 71  ? CE1 ? B PHE 43 CE1 
116 1 Y 1 P PHE 71  ? CE2 ? B PHE 43 CE2 
117 1 Y 1 P PHE 71  ? CZ  ? B PHE 43 CZ  
118 1 Y 1 P GLU 72  ? CB  ? B GLU 44 CB  
119 1 Y 1 P GLU 72  ? CG  ? B GLU 44 CG  
120 1 Y 1 P GLU 72  ? CD  ? B GLU 44 CD  
121 1 Y 1 P GLU 72  ? OE1 ? B GLU 44 OE1 
122 1 Y 1 P GLU 72  ? OE2 ? B GLU 44 OE2 
123 1 Y 1 P GLU 73  ? CB  ? B GLU 45 CB  
124 1 Y 1 P GLU 73  ? CG  ? B GLU 45 CG  
125 1 Y 1 P GLU 73  ? CD  ? B GLU 45 CD  
126 1 Y 1 P GLU 73  ? OE1 ? B GLU 45 OE1 
127 1 Y 1 P GLU 73  ? OE2 ? B GLU 45 OE2 
128 1 Y 1 P ARG 75  ? CB  ? B ARG 47 CB  
129 1 Y 1 P ARG 75  ? CG  ? B ARG 47 CG  
130 1 Y 1 P ARG 75  ? CD  ? B ARG 47 CD  
131 1 Y 1 P ARG 75  ? NE  ? B ARG 47 NE  
132 1 Y 1 P ARG 75  ? CZ  ? B ARG 47 CZ  
133 1 Y 1 P ARG 75  ? NH1 ? B ARG 47 NH1 
134 1 Y 1 P ARG 75  ? NH2 ? B ARG 47 NH2 
135 1 Y 1 P GLU 76  ? CB  ? B GLU 48 CB  
136 1 Y 1 P GLU 76  ? CG  ? B GLU 48 CG  
137 1 Y 1 P GLU 76  ? CD  ? B GLU 48 CD  
138 1 Y 1 P GLU 76  ? OE1 ? B GLU 48 OE1 
139 1 Y 1 P GLU 76  ? OE2 ? B GLU 48 OE2 
140 1 Y 1 P VAL 77  ? CB  ? B VAL 49 CB  
141 1 Y 1 P VAL 77  ? CG1 ? B VAL 49 CG1 
142 1 Y 1 P VAL 77  ? CG2 ? B VAL 49 CG2 
143 1 Y 1 P PHE 78  ? CB  ? B PHE 50 CB  
144 1 Y 1 P PHE 78  ? CG  ? B PHE 50 CG  
145 1 Y 1 P PHE 78  ? CD1 ? B PHE 50 CD1 
146 1 Y 1 P PHE 78  ? CD2 ? B PHE 50 CD2 
147 1 Y 1 P PHE 78  ? CE1 ? B PHE 50 CE1 
148 1 Y 1 P PHE 78  ? CE2 ? B PHE 50 CE2 
149 1 Y 1 P PHE 78  ? CZ  ? B PHE 50 CZ  
150 1 Y 1 P GLU 79  ? CB  ? B GLU 51 CB  
151 1 Y 1 P GLU 79  ? CG  ? B GLU 51 CG  
152 1 Y 1 P GLU 79  ? CD  ? B GLU 51 CD  
153 1 Y 1 P GLU 79  ? OE1 ? B GLU 51 OE1 
154 1 Y 1 P GLU 79  ? OE2 ? B GLU 51 OE2 
155 1 Y 1 P ASN 80  ? CB  ? B ASN 52 CB  
156 1 Y 1 P ASN 80  ? CG  ? B ASN 52 CG  
157 1 Y 1 P ASN 80  ? OD1 ? B ASN 52 OD1 
158 1 Y 1 P ASN 80  ? ND2 ? B ASN 52 ND2 
159 1 Y 1 P THR 81  ? CB  ? B THR 53 CB  
160 1 Y 1 P THR 81  ? OG1 ? B THR 53 OG1 
161 1 Y 1 P THR 81  ? CG2 ? B THR 53 CG2 
162 1 Y 1 P GLU 82  ? CB  ? B GLU 54 CB  
163 1 Y 1 P GLU 82  ? CG  ? B GLU 54 CG  
164 1 Y 1 P GLU 82  ? CD  ? B GLU 54 CD  
165 1 Y 1 P GLU 82  ? OE1 ? B GLU 54 OE1 
166 1 Y 1 P GLU 82  ? OE2 ? B GLU 54 OE2 
167 1 Y 1 P ARG 83  ? CB  ? B ARG 55 CB  
168 1 Y 1 P ARG 83  ? CG  ? B ARG 55 CG  
169 1 Y 1 P ARG 83  ? CD  ? B ARG 55 CD  
170 1 Y 1 P ARG 83  ? NE  ? B ARG 55 NE  
171 1 Y 1 P ARG 83  ? CZ  ? B ARG 55 CZ  
172 1 Y 1 P ARG 83  ? NH1 ? B ARG 55 NH1 
173 1 Y 1 P ARG 83  ? NH2 ? B ARG 55 NH2 
174 1 Y 1 P THR 84  ? CB  ? B THR 56 CB  
175 1 Y 1 P THR 84  ? OG1 ? B THR 56 OG1 
176 1 Y 1 P THR 84  ? CG2 ? B THR 56 CG2 
177 1 Y 1 P THR 85  ? CB  ? B THR 57 CB  
178 1 Y 1 P THR 85  ? OG1 ? B THR 57 OG1 
179 1 Y 1 P THR 85  ? CG2 ? B THR 57 CG2 
180 1 Y 1 P GLU 86  ? CB  ? B GLU 58 CB  
181 1 Y 1 P GLU 86  ? CG  ? B GLU 58 CG  
182 1 Y 1 P GLU 86  ? CD  ? B GLU 58 CD  
183 1 Y 1 P GLU 86  ? OE1 ? B GLU 58 OE1 
184 1 Y 1 P GLU 86  ? OE2 ? B GLU 58 OE2 
185 1 Y 1 P PHE 87  ? CB  ? B PHE 59 CB  
186 1 Y 1 P PHE 87  ? CG  ? B PHE 59 CG  
187 1 Y 1 P PHE 87  ? CD1 ? B PHE 59 CD1 
188 1 Y 1 P PHE 87  ? CD2 ? B PHE 59 CD2 
189 1 Y 1 P PHE 87  ? CE1 ? B PHE 59 CE1 
190 1 Y 1 P PHE 87  ? CE2 ? B PHE 59 CE2 
191 1 Y 1 P PHE 87  ? CZ  ? B PHE 59 CZ  
192 1 Y 1 P TRP 88  ? CB  ? B TRP 60 CB  
193 1 Y 1 P TRP 88  ? CG  ? B TRP 60 CG  
194 1 Y 1 P TRP 88  ? CD1 ? B TRP 60 CD1 
195 1 Y 1 P TRP 88  ? CD2 ? B TRP 60 CD2 
196 1 Y 1 P TRP 88  ? NE1 ? B TRP 60 NE1 
197 1 Y 1 P TRP 88  ? CE2 ? B TRP 60 CE2 
198 1 Y 1 P TRP 88  ? CE3 ? B TRP 60 CE3 
199 1 Y 1 P TRP 88  ? CZ2 ? B TRP 60 CZ2 
200 1 Y 1 P TRP 88  ? CZ3 ? B TRP 60 CZ3 
201 1 Y 1 P TRP 88  ? CH2 ? B TRP 60 CH2 
202 1 Y 1 P LYS 89  ? CB  ? B LYS 61 CB  
203 1 Y 1 P LYS 89  ? CG  ? B LYS 61 CG  
204 1 Y 1 P LYS 89  ? CD  ? B LYS 61 CD  
205 1 Y 1 P LYS 89  ? CE  ? B LYS 61 CE  
206 1 Y 1 P LYS 89  ? NZ  ? B LYS 61 NZ  
207 1 N 1 A 6PL 802 ? C26 ? G 6PL 1  C26 
208 1 N 1 A 6PL 802 ? C25 ? G 6PL 1  C25 
209 1 N 1 A 6PL 802 ? C24 ? G 6PL 1  C24 
210 1 N 1 A 6PL 802 ? C23 ? G 6PL 1  C23 
211 1 N 1 A 6PL 802 ? C47 ? G 6PL 1  C47 
212 1 N 1 A 6PL 802 ? C48 ? G 6PL 1  C48 
213 1 N 1 A 6PL 803 ? C47 ? H 6PL 1  C47 
214 1 N 1 A 6PL 803 ? C48 ? H 6PL 1  C48 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BVR 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BVR 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BVR 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9BVR 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003  ? 6422 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.593  ? 8687 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 10.300 ? 2492 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.038  ? 914  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005  ? 1093 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9BVR 
_struct.title                        
;Vitamin K-dependent gamma-carboxylase with factor IX propeptide and partially carboxylated glutamate-rich region and with vitamin K hydroquinone and calcium
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BVR 
_struct_keywords.text            
;GGCX, VKGC, Vitamin K, VKCFD, Hemophilia B, Warfarin, Carboxylation, Blood Coagulaton, Calcium homeostasis, MEMBRANE PROTEIN, LYASE-SUBSTRATE complex
;
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN,LYASE/SUBSTRATE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 3 ? 
F N N 4 ? 
G N N 5 ? 
H N N 5 ? 
I N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP VKGC_HUMAN P38435 ? 1 
;GPRQDSRIGKLLGFEWTDLSSWRRLVTLLNRPTDPASLAVFRFLFGFLMVLDIPQERGLSSLDRKYLDGLDVCRFPLLDA
LRPLPLDWMYLVYTIMFLGALGMMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGLL
NAHRRNAHVPLWNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKLLLSEELTSLLVVHWGGLLLDLSA
GFLLFFDVSRSIGLFFVSYFHCMNSQLFSIGMFSYVMLASSPLFCSPEWPRKLVSYCPRRLQQLLPLKAAPQPSVSCVYK
RSRGKSGQKPGLRHQLGAAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGYL
NPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAAWSPFQRTSWVQPLL
MDLSPWRAKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGEY
HKVYTTSPSPSCYMYVYVNTTELALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQRL
QEIERRRNTPFHERFFRFLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGELNPSNTDSSHSNP
PESNPDPVHSEF
;
27 
2 UNP FA9_HUMAN  P00740 ? 2 TVFLDHENANKILNRPKRYNSGKLEEFVQGNLERECMEEKCSFEEAREVFENTERTTEFWKQYV 29 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9BVR A 1 ? 732 ? P38435 27 ? 758 ? 27 758 
2 2 9BVR P 1 ? 64  ? P00740 29 ? 92  ? 29 92  
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 6   ? GLY A 13  ? SER A 32  GLY A 39  1 ? 8  
HELX_P HELX_P2  AA2 GLU A 15  ? SER A 20  ? GLU A 41  SER A 46  5 ? 6  
HELX_P HELX_P3  AA3 SER A 21  ? ASN A 30  ? SER A 47  ASN A 56  1 ? 10 
HELX_P HELX_P4  AA4 PRO A 35  ? ILE A 53  ? PRO A 61  ILE A 79  1 ? 19 
HELX_P HELX_P5  AA5 SER A 61  ? LYS A 65  ? SER A 87  LYS A 91  5 ? 5  
HELX_P HELX_P6  AA6 PRO A 85  ? GLY A 106 ? PRO A 111 GLY A 132 1 ? 22 
HELX_P HELX_P7  AA7 CYS A 108 ? ASP A 127 ? CYS A 134 ASP A 153 1 ? 20 
HELX_P HELX_P8  AA8 LYS A 128 ? TRP A 131 ? LYS A 154 TRP A 157 5 ? 4  
HELX_P HELX_P9  AA9 ASN A 132 ? THR A 146 ? ASN A 158 THR A 172 1 ? 15 
HELX_P HELX_P10 AB1 SER A 155 ? ASN A 161 ? SER A 181 ASN A 187 1 ? 7  
HELX_P HELX_P11 AB2 ALA A 162 ? ARG A 165 ? ALA A 188 ARG A 191 5 ? 4  
HELX_P HELX_P12 AB3 LEU A 171 ? LYS A 192 ? LEU A 197 LYS A 218 1 ? 22 
HELX_P HELX_P13 AB4 ASP A 194 ? GLU A 199 ? ASP A 220 GLU A 225 1 ? 6  
HELX_P HELX_P14 AB5 MET A 203 ? LEU A 211 ? MET A 229 LEU A 237 5 ? 9  
HELX_P HELX_P15 AB6 PHE A 212 ? LEU A 217 ? PHE A 238 LEU A 243 1 ? 6  
HELX_P HELX_P16 AB7 SER A 220 ? VAL A 228 ? SER A 246 VAL A 254 1 ? 9  
HELX_P HELX_P17 AB8 VAL A 229 ? LEU A 243 ? VAL A 255 LEU A 269 1 ? 15 
HELX_P HELX_P18 AB9 LEU A 244 ? PHE A 246 ? LEU A 270 PHE A 272 5 ? 3  
HELX_P HELX_P19 AC1 SER A 249 ? PHE A 268 ? SER A 275 PHE A 294 1 ? 20 
HELX_P HELX_P20 AC2 MET A 272 ? SER A 281 ? MET A 298 SER A 307 1 ? 10 
HELX_P HELX_P21 AC3 PRO A 282 ? CYS A 285 ? PRO A 308 CYS A 311 5 ? 4  
HELX_P HELX_P22 AC4 GLU A 288 ? TYR A 296 ? GLU A 314 TYR A 322 1 ? 9  
HELX_P HELX_P23 AC5 PRO A 298 ? GLN A 303 ? PRO A 324 GLN A 329 1 ? 6  
HELX_P HELX_P24 AC6 LEU A 332 ? LEU A 351 ? LEU A 358 LEU A 377 1 ? 20 
HELX_P HELX_P25 AC7 PRO A 352 ? SER A 354 ? PRO A 378 SER A 380 5 ? 3  
HELX_P HELX_P26 AC8 THR A 358 ? ASN A 362 ? THR A 384 ASN A 388 5 ? 5  
HELX_P HELX_P27 AC9 ARG A 409 ? ASP A 413 ? ARG A 435 ASP A 439 5 ? 5  
HELX_P HELX_P28 AD1 HIS A 414 ? LEU A 429 ? HIS A 440 LEU A 455 1 ? 16 
HELX_P HELX_P29 AD2 PRO A 430 ? ASN A 433 ? PRO A 456 ASN A 459 5 ? 4  
HELX_P HELX_P30 AD3 LEU A 480 ? PRO A 485 ? LEU A 506 PRO A 511 5 ? 6  
HELX_P HELX_P31 AD4 TRP A 486 ? SER A 496 ? TRP A 512 SER A 522 1 ? 11 
HELX_P HELX_P32 AD5 ASN A 579 ? ASN A 601 ? ASN A 605 ASN A 627 1 ? 23 
HELX_P HELX_P33 AD6 GLU A 611 ? GLY A 618 ? GLU A 637 GLY A 644 1 ? 8  
HELX_P HELX_P34 AD7 THR A 627 ? ASN A 648 ? THR A 653 ASN A 674 1 ? 22 
HELX_P HELX_P35 AD8 PRO A 650 ? GLY A 683 ? PRO A 676 GLY A 709 1 ? 34 
HELX_P HELX_P36 AD9 SER A 686 ? ASN A 698 ? SER A 712 ASN A 724 1 ? 13 
HELX_P HELX_P37 AE1 ASP B 5   ? ASN B 10  ? ASP P 33  ASN P 38  1 ? 6  
HELX_P HELX_P38 AE2 ARG B 15  ? PHE B 27  ? ARG P 43  PHE P 55  1 ? 13 
HELX_P HELX_P39 AE3 ASN B 31  ? LYS B 40  ? ASN P 59  LYS P 68  1 ? 10 
HELX_P HELX_P40 AE4 SER B 42  ? PHE B 50  ? SER P 70  PHE P 78  1 ? 9  
HELX_P HELX_P41 AE5 GLU B 54  ? LYS B 61  ? GLU P 82  LYS P 89  1 ? 8  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 73  SG  ? ? ? 1_555 A CYS 424 SG ? ? A CYS 99  A CYS 450 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
covale1 covale one  ? A ASN 433 ND2 ? ? ? 1_555 I NAG .   C1 ? ? A ASN 459 A NAG 804 1_555 ? ? ? ? ? ? ? 1.552 ? N-Glycosylation 
covale2 covale one  ? A ASN 524 ND2 ? ? ? 1_555 D NAG .   C1 ? ? A ASN 550 C NAG 1   1_555 ? ? ? ? ? ? ? 1.489 ? N-Glycosylation 
covale3 covale one  ? A ASN 544 ND2 ? ? ? 1_555 C NAG .   C1 ? ? A ASN 570 B NAG 1   1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale4 covale one  ? A ASN 579 ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 605 D NAG 1   1_555 ? ? ? ? ? ? ? 1.440 ? N-Glycosylation 
covale5 covale both ? C NAG .   O4  ? ? ? 1_555 C NAG .   C1 ? ? B NAG 1   B NAG 2   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale6 covale both ? D NAG .   O4  ? ? ? 1_555 D NAG .   C1 ? ? C NAG 1   C NAG 2   1_555 ? ? ? ? ? ? ? 1.442 ? ?               
covale7 covale both ? E NAG .   O4  ? ? ? 1_555 E NAG .   C1 ? ? D NAG 1   D NAG 2   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG C .  ? ASN A 544 ? NAG B 1   ? 1_555 ASN A 570 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 NAG D .  ? ASN A 524 ? NAG C 1   ? 1_555 ASN A 550 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3 NAG E .  ? ASN A 579 ? NAG D 1   ? 1_555 ASN A 605 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4 NAG I .  ? ASN A 433 ? NAG A 804 ? 1_555 ASN A 459 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5 CYS A 73 ? CYS A 424 ? CYS A 99  ? 1_555 CYS A 450 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 5 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PRO A 32  ? THR A 33  ? PRO A 58  THR A 59  
AA1 2 VAL A 169 ? PRO A 170 ? VAL A 195 PRO A 196 
AA2 1 GLN A 453 ? ARG A 454 ? GLN A 479 ARG A 480 
AA2 2 GLN A 438 ? ILE A 447 ? GLN A 464 ILE A 473 
AA2 3 ARG A 380 ? ARG A 390 ? ARG A 406 ARG A 416 
AA2 4 LEU A 397 ? LEU A 400 ? LEU A 423 LEU A 426 
AA2 5 PHE B 3   ? LEU B 4   ? PHE P 31  LEU P 32  
AA3 1 GLU A 502 ? ASP A 508 ? GLU A 528 ASP A 534 
AA3 2 SER A 571 ? TYR A 577 ? SER A 597 TYR A 603 
AA3 3 THR A 525 ? GLN A 531 ? THR A 551 GLN A 557 
AA3 4 LYS A 552 ? GLN A 554 ? LYS A 578 GLN A 580 
AA4 1 HIS A 513 ? PHE A 517 ? HIS A 539 PHE A 543 
AA4 2 TYR A 560 ? THR A 565 ? TYR A 586 THR A 591 
AA4 3 VAL A 534 ? LEU A 538 ? VAL A 560 LEU A 564 
AA4 4 LYS A 543 ? LEU A 547 ? LYS A 569 LEU A 573 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR A 33  ? N THR A 59  O VAL A 169 ? O VAL A 195 
AA2 1 2 O GLN A 453 ? O GLN A 479 N VAL A 445 ? N VAL A 471 
AA2 2 3 O TYR A 440 ? O TYR A 466 N THR A 388 ? N THR A 414 
AA2 3 4 N TYR A 389 ? N TYR A 415 O GLY A 398 ? O GLY A 424 
AA2 4 5 N TYR A 399 ? N TYR A 425 O LEU B 4   ? O LEU P 32  
AA3 1 2 N ASP A 508 ? N ASP A 534 O SER A 571 ? O SER A 597 
AA3 2 3 O VAL A 576 ? O VAL A 602 N SER A 526 ? N SER A 552 
AA3 3 4 N ILE A 527 ? N ILE A 553 O MET A 553 ? O MET A 579 
AA4 1 2 N ASN A 516 ? N ASN A 542 O HIS A 561 ? O HIS A 587 
AA4 2 3 O TYR A 564 ? O TYR A 590 N THR A 535 ? N THR A 561 
AA4 3 4 N LEU A 538 ? N LEU A 564 O LYS A 543 ? O LYS A 569 
# 
_pdbx_entry_details.entry_id                   9BVR 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 ND2 A ASN 459 ? ? O5 A NAG 804 ? ? 1.31 
2  1 ND2 A ASN 605 ? ? O5 D NAG 1   ? ? 1.45 
3  1 O4  B NAG 1   ? ? O5 B NAG 2   ? ? 1.73 
4  1 O4  D NAG 1   ? ? O5 D NAG 2   ? ? 1.78 
5  1 ND2 A ASN 570 ? ? O5 B NAG 1   ? ? 2.01 
6  1 O   A ASP 60  ? ? OH A TYR 200 ? ? 2.10 
7  1 CG  A ASN 550 ? ? C1 C NAG 1   ? ? 2.14 
8  1 O4  C NAG 1   ? ? O5 C NAG 2   ? ? 2.17 
9  1 ND2 A ASN 459 ? ? C2 A NAG 804 ? ? 2.17 
10 1 O   A TRP 236 ? ? OG A SER 239 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASN A 389 ? ? -149.15 -159.85 
2 1 THR A 461 ? ? -78.83  -168.64 
3 1 GLU A 462 ? ? -56.79  106.82  
4 1 ASN A 550 ? ? 60.20   60.05   
5 1 ARG P 43  ? ? -58.56  108.04  
6 1 ASN P 59  ? ? 69.58   -76.46  
7 1 PHE P 78  ? ? 74.59   -3.75   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9BVR 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      OTHER 
# 
_em_3d_reconstruction.entry_id                    9BVR 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.5 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               173076 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
;Vitamin K-dependent gamma-carboxylase with factor IX propeptide and partially carboxylated glutamate-rich region and with vitamin K hydroquinone and calcium
;
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_image_scans.entry_id                9BVR 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        5760 
_em_image_scans.dimension_width         4092 
_em_image_scans.frames_per_image        ? 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        9BVR 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           130000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   63 
_em_imaging.recording_temperature_maximum   77 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            50.0 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9BVR 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              95 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   283.15 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9BVR 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY 27  ? A GLY 1   
2  1 Y 1 A PRO 28  ? A PRO 2   
3  1 Y 1 A ARG 29  ? A ARG 3   
4  1 Y 1 A GLN 30  ? A GLN 4   
5  1 Y 1 A SER 348 ? A SER 322 
6  1 Y 1 A ARG 349 ? A ARG 323 
7  1 Y 1 A GLY 350 ? A GLY 324 
8  1 Y 1 A LYS 351 ? A LYS 325 
9  1 Y 1 A SER 352 ? A SER 326 
10 1 Y 1 A GLU 729 ? A GLU 703 
11 1 Y 1 A ALA 730 ? A ALA 704 
12 1 Y 1 A VAL 731 ? A VAL 705 
13 1 Y 1 A GLY 732 ? A GLY 706 
14 1 Y 1 A GLU 733 ? A GLU 707 
15 1 Y 1 A LEU 734 ? A LEU 708 
16 1 Y 1 A ASN 735 ? A ASN 709 
17 1 Y 1 A PRO 736 ? A PRO 710 
18 1 Y 1 A SER 737 ? A SER 711 
19 1 Y 1 A ASN 738 ? A ASN 712 
20 1 Y 1 A THR 739 ? A THR 713 
21 1 Y 1 A ASP 740 ? A ASP 714 
22 1 Y 1 A SER 741 ? A SER 715 
23 1 Y 1 A SER 742 ? A SER 716 
24 1 Y 1 A HIS 743 ? A HIS 717 
25 1 Y 1 A SER 744 ? A SER 718 
26 1 Y 1 A ASN 745 ? A ASN 719 
27 1 Y 1 A PRO 746 ? A PRO 720 
28 1 Y 1 A PRO 747 ? A PRO 721 
29 1 Y 1 A GLU 748 ? A GLU 722 
30 1 Y 1 A SER 749 ? A SER 723 
31 1 Y 1 A ASN 750 ? A ASN 724 
32 1 Y 1 A PRO 751 ? A PRO 725 
33 1 Y 1 A ASP 752 ? A ASP 726 
34 1 Y 1 A PRO 753 ? A PRO 727 
35 1 Y 1 A VAL 754 ? A VAL 728 
36 1 Y 1 A HIS 755 ? A HIS 729 
37 1 Y 1 A SER 756 ? A SER 730 
38 1 Y 1 A GLU 757 ? A GLU 731 
39 1 Y 1 A PHE 758 ? A PHE 732 
40 1 Y 1 P GLN 90  ? B GLN 62  
41 1 Y 1 P TYR 91  ? B TYR 63  
42 1 Y 1 P VAL 92  ? B VAL 64  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
6PL   C26  C N N 1   
6PL   C25  C N N 2   
6PL   C24  C N N 3   
6PL   C23  C N N 4   
6PL   C22  C N N 5   
6PL   C21  C N N 6   
6PL   C20  C N N 7   
6PL   C19  C N N 8   
6PL   C18  C N N 9   
6PL   C17  C N N 10  
6PL   C16  C N N 11  
6PL   C15  C N N 12  
6PL   C14  C N N 13  
6PL   C13  C N N 14  
6PL   C12  C N N 15  
6PL   C11  C N N 16  
6PL   O11  O N N 17  
6PL   O3   O N N 18  
6PL   C3   C N N 19  
6PL   C2   C N R 20  
6PL   C1   C N N 21  
6PL   O3P  O N N 22  
6PL   P    P N S 23  
6PL   O1P  O N N 24  
6PL   O2P  O N N 25  
6PL   O4P  O N N 26  
6PL   C4   C N N 27  
6PL   C5   C N N 28  
6PL   N    N N N 29  
6PL   C7   C N N 30  
6PL   C8   C N N 31  
6PL   C6   C N N 32  
6PL   O2   O N N 33  
6PL   C31  C N N 34  
6PL   O31  O N N 35  
6PL   C32  C N N 36  
6PL   C33  C N N 37  
6PL   C34  C N N 38  
6PL   C35  C N N 39  
6PL   C36  C N N 40  
6PL   C37  C N N 41  
6PL   C38  C N N 42  
6PL   C39  C N N 43  
6PL   C40  C N N 44  
6PL   C41  C N N 45  
6PL   C42  C N N 46  
6PL   C43  C N N 47  
6PL   C44  C N N 48  
6PL   C45  C N N 49  
6PL   C46  C N N 50  
6PL   C47  C N N 51  
6PL   C48  C N N 52  
6PL   H261 H N N 53  
6PL   H262 H N N 54  
6PL   H263 H N N 55  
6PL   H251 H N N 56  
6PL   H252 H N N 57  
6PL   H241 H N N 58  
6PL   H242 H N N 59  
6PL   H231 H N N 60  
6PL   H232 H N N 61  
6PL   H221 H N N 62  
6PL   H222 H N N 63  
6PL   H211 H N N 64  
6PL   H212 H N N 65  
6PL   H201 H N N 66  
6PL   H202 H N N 67  
6PL   H191 H N N 68  
6PL   H192 H N N 69  
6PL   H181 H N N 70  
6PL   H182 H N N 71  
6PL   H171 H N N 72  
6PL   H172 H N N 73  
6PL   H161 H N N 74  
6PL   H162 H N N 75  
6PL   H151 H N N 76  
6PL   H152 H N N 77  
6PL   H141 H N N 78  
6PL   H142 H N N 79  
6PL   H131 H N N 80  
6PL   H132 H N N 81  
6PL   H121 H N N 82  
6PL   H122 H N N 83  
6PL   H31  H N N 84  
6PL   H32  H N N 85  
6PL   H2   H N N 86  
6PL   H11  H N N 87  
6PL   H12  H N N 88  
6PL   H2P  H N N 89  
6PL   H41  H N N 90  
6PL   H42  H N N 91  
6PL   H51  H N N 92  
6PL   H52  H N N 93  
6PL   H71  H N N 94  
6PL   H72  H N N 95  
6PL   H73  H N N 96  
6PL   H81  H N N 97  
6PL   H82  H N N 98  
6PL   H83  H N N 99  
6PL   H61  H N N 100 
6PL   H62  H N N 101 
6PL   H63  H N N 102 
6PL   H321 H N N 103 
6PL   H322 H N N 104 
6PL   H331 H N N 105 
6PL   H332 H N N 106 
6PL   H341 H N N 107 
6PL   H342 H N N 108 
6PL   H351 H N N 109 
6PL   H352 H N N 110 
6PL   H361 H N N 111 
6PL   H362 H N N 112 
6PL   H371 H N N 113 
6PL   H372 H N N 114 
6PL   H381 H N N 115 
6PL   H382 H N N 116 
6PL   H391 H N N 117 
6PL   H392 H N N 118 
6PL   H401 H N N 119 
6PL   H402 H N N 120 
6PL   H411 H N N 121 
6PL   H412 H N N 122 
6PL   H421 H N N 123 
6PL   H422 H N N 124 
6PL   H431 H N N 125 
6PL   H432 H N N 126 
6PL   H441 H N N 127 
6PL   H442 H N N 128 
6PL   H451 H N N 129 
6PL   H452 H N N 130 
6PL   H461 H N N 131 
6PL   H462 H N N 132 
6PL   H471 H N N 133 
6PL   H472 H N N 134 
6PL   H481 H N N 135 
6PL   H482 H N N 136 
6PL   H483 H N N 137 
A1AVC C11  C Y N 138 
A1AVC C12  C N N 139 
A1AVC C13  C N N 140 
A1AVC C14  C N N 141 
A1AVC C15  C N N 142 
A1AVC C16  C N N 143 
A1AVC C01  C N N 144 
A1AVC C02  C Y N 145 
A1AVC C03  C Y N 146 
A1AVC C04  C Y N 147 
A1AVC C05  C Y N 148 
A1AVC C06  C Y N 149 
A1AVC C07  C Y N 150 
A1AVC C08  C Y N 151 
A1AVC C09  C Y N 152 
A1AVC C10  C Y N 153 
A1AVC C17  C N N 154 
A1AVC C18  C N N 155 
A1AVC C19  C N R 156 
A1AVC C20  C N N 157 
A1AVC C21  C N N 158 
A1AVC C22  C N N 159 
A1AVC C23  C N N 160 
A1AVC C24  C N R 161 
A1AVC C25  C N N 162 
A1AVC C26  C N N 163 
A1AVC C27  C N N 164 
A1AVC C28  C N N 165 
A1AVC C29  C N N 166 
A1AVC C30  C N N 167 
A1AVC C31  C N N 168 
A1AVC O32  O N N 169 
A1AVC O33  O N N 170 
A1AVC H1   H N N 171 
A1AVC H2   H N N 172 
A1AVC H3   H N N 173 
A1AVC H4   H N N 174 
A1AVC H5   H N N 175 
A1AVC H6   H N N 176 
A1AVC H7   H N N 177 
A1AVC H8   H N N 178 
A1AVC H9   H N N 179 
A1AVC H10  H N N 180 
A1AVC H11  H N N 181 
A1AVC H12  H N N 182 
A1AVC H13  H N N 183 
A1AVC H14  H N N 184 
A1AVC H15  H N N 185 
A1AVC H16  H N N 186 
A1AVC H17  H N N 187 
A1AVC H18  H N N 188 
A1AVC H19  H N N 189 
A1AVC H20  H N N 190 
A1AVC H21  H N N 191 
A1AVC H22  H N N 192 
A1AVC H23  H N N 193 
A1AVC H24  H N N 194 
A1AVC H25  H N N 195 
A1AVC H26  H N N 196 
A1AVC H27  H N N 197 
A1AVC H28  H N N 198 
A1AVC H29  H N N 199 
A1AVC H30  H N N 200 
A1AVC H31  H N N 201 
A1AVC H32  H N N 202 
A1AVC H33  H N N 203 
A1AVC H34  H N N 204 
A1AVC H35  H N N 205 
A1AVC H36  H N N 206 
A1AVC H37  H N N 207 
A1AVC H38  H N N 208 
A1AVC H39  H N N 209 
A1AVC H40  H N N 210 
A1AVC H41  H N N 211 
A1AVC H42  H N N 212 
A1AVC H43  H N N 213 
A1AVC H44  H N N 214 
A1AVC H45  H N N 215 
A1AVC H46  H N N 216 
A1AVC H47  H N N 217 
A1AVC H48  H N N 218 
ALA   N    N N N 219 
ALA   CA   C N S 220 
ALA   C    C N N 221 
ALA   O    O N N 222 
ALA   CB   C N N 223 
ALA   OXT  O N N 224 
ALA   H    H N N 225 
ALA   H2   H N N 226 
ALA   HA   H N N 227 
ALA   HB1  H N N 228 
ALA   HB2  H N N 229 
ALA   HB3  H N N 230 
ALA   HXT  H N N 231 
ARG   N    N N N 232 
ARG   CA   C N S 233 
ARG   C    C N N 234 
ARG   O    O N N 235 
ARG   CB   C N N 236 
ARG   CG   C N N 237 
ARG   CD   C N N 238 
ARG   NE   N N N 239 
ARG   CZ   C N N 240 
ARG   NH1  N N N 241 
ARG   NH2  N N N 242 
ARG   OXT  O N N 243 
ARG   H    H N N 244 
ARG   H2   H N N 245 
ARG   HA   H N N 246 
ARG   HB2  H N N 247 
ARG   HB3  H N N 248 
ARG   HG2  H N N 249 
ARG   HG3  H N N 250 
ARG   HD2  H N N 251 
ARG   HD3  H N N 252 
ARG   HE   H N N 253 
ARG   HH11 H N N 254 
ARG   HH12 H N N 255 
ARG   HH21 H N N 256 
ARG   HH22 H N N 257 
ARG   HXT  H N N 258 
ASN   N    N N N 259 
ASN   CA   C N S 260 
ASN   C    C N N 261 
ASN   O    O N N 262 
ASN   CB   C N N 263 
ASN   CG   C N N 264 
ASN   OD1  O N N 265 
ASN   ND2  N N N 266 
ASN   OXT  O N N 267 
ASN   H    H N N 268 
ASN   H2   H N N 269 
ASN   HA   H N N 270 
ASN   HB2  H N N 271 
ASN   HB3  H N N 272 
ASN   HD21 H N N 273 
ASN   HD22 H N N 274 
ASN   HXT  H N N 275 
ASP   N    N N N 276 
ASP   CA   C N S 277 
ASP   C    C N N 278 
ASP   O    O N N 279 
ASP   CB   C N N 280 
ASP   CG   C N N 281 
ASP   OD1  O N N 282 
ASP   OD2  O N N 283 
ASP   OXT  O N N 284 
ASP   H    H N N 285 
ASP   H2   H N N 286 
ASP   HA   H N N 287 
ASP   HB2  H N N 288 
ASP   HB3  H N N 289 
ASP   HD2  H N N 290 
ASP   HXT  H N N 291 
CYS   N    N N N 292 
CYS   CA   C N R 293 
CYS   C    C N N 294 
CYS   O    O N N 295 
CYS   CB   C N N 296 
CYS   SG   S N N 297 
CYS   OXT  O N N 298 
CYS   H    H N N 299 
CYS   H2   H N N 300 
CYS   HA   H N N 301 
CYS   HB2  H N N 302 
CYS   HB3  H N N 303 
CYS   HG   H N N 304 
CYS   HXT  H N N 305 
GLN   N    N N N 306 
GLN   CA   C N S 307 
GLN   C    C N N 308 
GLN   O    O N N 309 
GLN   CB   C N N 310 
GLN   CG   C N N 311 
GLN   CD   C N N 312 
GLN   OE1  O N N 313 
GLN   NE2  N N N 314 
GLN   OXT  O N N 315 
GLN   H    H N N 316 
GLN   H2   H N N 317 
GLN   HA   H N N 318 
GLN   HB2  H N N 319 
GLN   HB3  H N N 320 
GLN   HG2  H N N 321 
GLN   HG3  H N N 322 
GLN   HE21 H N N 323 
GLN   HE22 H N N 324 
GLN   HXT  H N N 325 
GLU   N    N N N 326 
GLU   CA   C N S 327 
GLU   C    C N N 328 
GLU   O    O N N 329 
GLU   CB   C N N 330 
GLU   CG   C N N 331 
GLU   CD   C N N 332 
GLU   OE1  O N N 333 
GLU   OE2  O N N 334 
GLU   OXT  O N N 335 
GLU   H    H N N 336 
GLU   H2   H N N 337 
GLU   HA   H N N 338 
GLU   HB2  H N N 339 
GLU   HB3  H N N 340 
GLU   HG2  H N N 341 
GLU   HG3  H N N 342 
GLU   HE2  H N N 343 
GLU   HXT  H N N 344 
GLY   N    N N N 345 
GLY   CA   C N N 346 
GLY   C    C N N 347 
GLY   O    O N N 348 
GLY   OXT  O N N 349 
GLY   H    H N N 350 
GLY   H2   H N N 351 
GLY   HA2  H N N 352 
GLY   HA3  H N N 353 
GLY   HXT  H N N 354 
HIS   N    N N N 355 
HIS   CA   C N S 356 
HIS   C    C N N 357 
HIS   O    O N N 358 
HIS   CB   C N N 359 
HIS   CG   C Y N 360 
HIS   ND1  N Y N 361 
HIS   CD2  C Y N 362 
HIS   CE1  C Y N 363 
HIS   NE2  N Y N 364 
HIS   OXT  O N N 365 
HIS   H    H N N 366 
HIS   H2   H N N 367 
HIS   HA   H N N 368 
HIS   HB2  H N N 369 
HIS   HB3  H N N 370 
HIS   HD1  H N N 371 
HIS   HD2  H N N 372 
HIS   HE1  H N N 373 
HIS   HE2  H N N 374 
HIS   HXT  H N N 375 
ILE   N    N N N 376 
ILE   CA   C N S 377 
ILE   C    C N N 378 
ILE   O    O N N 379 
ILE   CB   C N S 380 
ILE   CG1  C N N 381 
ILE   CG2  C N N 382 
ILE   CD1  C N N 383 
ILE   OXT  O N N 384 
ILE   H    H N N 385 
ILE   H2   H N N 386 
ILE   HA   H N N 387 
ILE   HB   H N N 388 
ILE   HG12 H N N 389 
ILE   HG13 H N N 390 
ILE   HG21 H N N 391 
ILE   HG22 H N N 392 
ILE   HG23 H N N 393 
ILE   HD11 H N N 394 
ILE   HD12 H N N 395 
ILE   HD13 H N N 396 
ILE   HXT  H N N 397 
LEU   N    N N N 398 
LEU   CA   C N S 399 
LEU   C    C N N 400 
LEU   O    O N N 401 
LEU   CB   C N N 402 
LEU   CG   C N N 403 
LEU   CD1  C N N 404 
LEU   CD2  C N N 405 
LEU   OXT  O N N 406 
LEU   H    H N N 407 
LEU   H2   H N N 408 
LEU   HA   H N N 409 
LEU   HB2  H N N 410 
LEU   HB3  H N N 411 
LEU   HG   H N N 412 
LEU   HD11 H N N 413 
LEU   HD12 H N N 414 
LEU   HD13 H N N 415 
LEU   HD21 H N N 416 
LEU   HD22 H N N 417 
LEU   HD23 H N N 418 
LEU   HXT  H N N 419 
LYS   N    N N N 420 
LYS   CA   C N S 421 
LYS   C    C N N 422 
LYS   O    O N N 423 
LYS   CB   C N N 424 
LYS   CG   C N N 425 
LYS   CD   C N N 426 
LYS   CE   C N N 427 
LYS   NZ   N N N 428 
LYS   OXT  O N N 429 
LYS   H    H N N 430 
LYS   H2   H N N 431 
LYS   HA   H N N 432 
LYS   HB2  H N N 433 
LYS   HB3  H N N 434 
LYS   HG2  H N N 435 
LYS   HG3  H N N 436 
LYS   HD2  H N N 437 
LYS   HD3  H N N 438 
LYS   HE2  H N N 439 
LYS   HE3  H N N 440 
LYS   HZ1  H N N 441 
LYS   HZ2  H N N 442 
LYS   HZ3  H N N 443 
LYS   HXT  H N N 444 
MET   N    N N N 445 
MET   CA   C N S 446 
MET   C    C N N 447 
MET   O    O N N 448 
MET   CB   C N N 449 
MET   CG   C N N 450 
MET   SD   S N N 451 
MET   CE   C N N 452 
MET   OXT  O N N 453 
MET   H    H N N 454 
MET   H2   H N N 455 
MET   HA   H N N 456 
MET   HB2  H N N 457 
MET   HB3  H N N 458 
MET   HG2  H N N 459 
MET   HG3  H N N 460 
MET   HE1  H N N 461 
MET   HE2  H N N 462 
MET   HE3  H N N 463 
MET   HXT  H N N 464 
NAG   C1   C N R 465 
NAG   C2   C N R 466 
NAG   C3   C N R 467 
NAG   C4   C N S 468 
NAG   C5   C N R 469 
NAG   C6   C N N 470 
NAG   C7   C N N 471 
NAG   C8   C N N 472 
NAG   N2   N N N 473 
NAG   O1   O N N 474 
NAG   O3   O N N 475 
NAG   O4   O N N 476 
NAG   O5   O N N 477 
NAG   O6   O N N 478 
NAG   O7   O N N 479 
NAG   H1   H N N 480 
NAG   H2   H N N 481 
NAG   H3   H N N 482 
NAG   H4   H N N 483 
NAG   H5   H N N 484 
NAG   H61  H N N 485 
NAG   H62  H N N 486 
NAG   H81  H N N 487 
NAG   H82  H N N 488 
NAG   H83  H N N 489 
NAG   HN2  H N N 490 
NAG   HO1  H N N 491 
NAG   HO3  H N N 492 
NAG   HO4  H N N 493 
NAG   HO6  H N N 494 
PHE   N    N N N 495 
PHE   CA   C N S 496 
PHE   C    C N N 497 
PHE   O    O N N 498 
PHE   CB   C N N 499 
PHE   CG   C Y N 500 
PHE   CD1  C Y N 501 
PHE   CD2  C Y N 502 
PHE   CE1  C Y N 503 
PHE   CE2  C Y N 504 
PHE   CZ   C Y N 505 
PHE   OXT  O N N 506 
PHE   H    H N N 507 
PHE   H2   H N N 508 
PHE   HA   H N N 509 
PHE   HB2  H N N 510 
PHE   HB3  H N N 511 
PHE   HD1  H N N 512 
PHE   HD2  H N N 513 
PHE   HE1  H N N 514 
PHE   HE2  H N N 515 
PHE   HZ   H N N 516 
PHE   HXT  H N N 517 
PRO   N    N N N 518 
PRO   CA   C N S 519 
PRO   C    C N N 520 
PRO   O    O N N 521 
PRO   CB   C N N 522 
PRO   CG   C N N 523 
PRO   CD   C N N 524 
PRO   OXT  O N N 525 
PRO   H    H N N 526 
PRO   HA   H N N 527 
PRO   HB2  H N N 528 
PRO   HB3  H N N 529 
PRO   HG2  H N N 530 
PRO   HG3  H N N 531 
PRO   HD2  H N N 532 
PRO   HD3  H N N 533 
PRO   HXT  H N N 534 
SER   N    N N N 535 
SER   CA   C N S 536 
SER   C    C N N 537 
SER   O    O N N 538 
SER   CB   C N N 539 
SER   OG   O N N 540 
SER   OXT  O N N 541 
SER   H    H N N 542 
SER   H2   H N N 543 
SER   HA   H N N 544 
SER   HB2  H N N 545 
SER   HB3  H N N 546 
SER   HG   H N N 547 
SER   HXT  H N N 548 
THR   N    N N N 549 
THR   CA   C N S 550 
THR   C    C N N 551 
THR   O    O N N 552 
THR   CB   C N R 553 
THR   OG1  O N N 554 
THR   CG2  C N N 555 
THR   OXT  O N N 556 
THR   H    H N N 557 
THR   H2   H N N 558 
THR   HA   H N N 559 
THR   HB   H N N 560 
THR   HG1  H N N 561 
THR   HG21 H N N 562 
THR   HG22 H N N 563 
THR   HG23 H N N 564 
THR   HXT  H N N 565 
TRP   N    N N N 566 
TRP   CA   C N S 567 
TRP   C    C N N 568 
TRP   O    O N N 569 
TRP   CB   C N N 570 
TRP   CG   C Y N 571 
TRP   CD1  C Y N 572 
TRP   CD2  C Y N 573 
TRP   NE1  N Y N 574 
TRP   CE2  C Y N 575 
TRP   CE3  C Y N 576 
TRP   CZ2  C Y N 577 
TRP   CZ3  C Y N 578 
TRP   CH2  C Y N 579 
TRP   OXT  O N N 580 
TRP   H    H N N 581 
TRP   H2   H N N 582 
TRP   HA   H N N 583 
TRP   HB2  H N N 584 
TRP   HB3  H N N 585 
TRP   HD1  H N N 586 
TRP   HE1  H N N 587 
TRP   HE3  H N N 588 
TRP   HZ2  H N N 589 
TRP   HZ3  H N N 590 
TRP   HH2  H N N 591 
TRP   HXT  H N N 592 
TYR   N    N N N 593 
TYR   CA   C N S 594 
TYR   C    C N N 595 
TYR   O    O N N 596 
TYR   CB   C N N 597 
TYR   CG   C Y N 598 
TYR   CD1  C Y N 599 
TYR   CD2  C Y N 600 
TYR   CE1  C Y N 601 
TYR   CE2  C Y N 602 
TYR   CZ   C Y N 603 
TYR   OH   O N N 604 
TYR   OXT  O N N 605 
TYR   H    H N N 606 
TYR   H2   H N N 607 
TYR   HA   H N N 608 
TYR   HB2  H N N 609 
TYR   HB3  H N N 610 
TYR   HD1  H N N 611 
TYR   HD2  H N N 612 
TYR   HE1  H N N 613 
TYR   HE2  H N N 614 
TYR   HH   H N N 615 
TYR   HXT  H N N 616 
VAL   N    N N N 617 
VAL   CA   C N S 618 
VAL   C    C N N 619 
VAL   O    O N N 620 
VAL   CB   C N N 621 
VAL   CG1  C N N 622 
VAL   CG2  C N N 623 
VAL   OXT  O N N 624 
VAL   H    H N N 625 
VAL   H2   H N N 626 
VAL   HA   H N N 627 
VAL   HB   H N N 628 
VAL   HG11 H N N 629 
VAL   HG12 H N N 630 
VAL   HG13 H N N 631 
VAL   HG21 H N N 632 
VAL   HG22 H N N 633 
VAL   HG23 H N N 634 
VAL   HXT  H N N 635 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
6PL   C26 C25  sing N N 1   
6PL   C26 H261 sing N N 2   
6PL   C26 H262 sing N N 3   
6PL   C26 H263 sing N N 4   
6PL   C25 C24  sing N N 5   
6PL   C25 H251 sing N N 6   
6PL   C25 H252 sing N N 7   
6PL   C24 C23  sing N N 8   
6PL   C24 H241 sing N N 9   
6PL   C24 H242 sing N N 10  
6PL   C23 C22  sing N N 11  
6PL   C23 H231 sing N N 12  
6PL   C23 H232 sing N N 13  
6PL   C22 C21  sing N N 14  
6PL   C22 H221 sing N N 15  
6PL   C22 H222 sing N N 16  
6PL   C21 C20  sing N N 17  
6PL   C21 H211 sing N N 18  
6PL   C21 H212 sing N N 19  
6PL   C20 C19  sing N N 20  
6PL   C20 H201 sing N N 21  
6PL   C20 H202 sing N N 22  
6PL   C19 C18  sing N N 23  
6PL   C19 H191 sing N N 24  
6PL   C19 H192 sing N N 25  
6PL   C18 C17  sing N N 26  
6PL   C18 H181 sing N N 27  
6PL   C18 H182 sing N N 28  
6PL   C17 C16  sing N N 29  
6PL   C17 H171 sing N N 30  
6PL   C17 H172 sing N N 31  
6PL   C16 C15  sing N N 32  
6PL   C16 H161 sing N N 33  
6PL   C16 H162 sing N N 34  
6PL   C15 C14  sing N N 35  
6PL   C15 H151 sing N N 36  
6PL   C15 H152 sing N N 37  
6PL   C14 C13  sing N N 38  
6PL   C14 H141 sing N N 39  
6PL   C14 H142 sing N N 40  
6PL   C13 C12  sing N N 41  
6PL   C13 H131 sing N N 42  
6PL   C13 H132 sing N N 43  
6PL   C12 C11  sing N N 44  
6PL   C12 H121 sing N N 45  
6PL   C12 H122 sing N N 46  
6PL   C11 O11  doub N N 47  
6PL   C11 O3   sing N N 48  
6PL   O3  C3   sing N N 49  
6PL   C3  C2   sing N N 50  
6PL   C3  H31  sing N N 51  
6PL   C3  H32  sing N N 52  
6PL   C2  C1   sing N N 53  
6PL   C2  O2   sing N N 54  
6PL   C2  H2   sing N N 55  
6PL   C1  O3P  sing N N 56  
6PL   C1  H11  sing N N 57  
6PL   C1  H12  sing N N 58  
6PL   O3P P    sing N N 59  
6PL   P   O1P  doub N N 60  
6PL   P   O2P  sing N N 61  
6PL   P   O4P  sing N N 62  
6PL   O2P H2P  sing N N 63  
6PL   O4P C4   sing N N 64  
6PL   C4  C5   sing N N 65  
6PL   C4  H41  sing N N 66  
6PL   C4  H42  sing N N 67  
6PL   C5  N    sing N N 68  
6PL   C5  H51  sing N N 69  
6PL   C5  H52  sing N N 70  
6PL   N   C7   sing N N 71  
6PL   N   C8   sing N N 72  
6PL   N   C6   sing N N 73  
6PL   C7  H71  sing N N 74  
6PL   C7  H72  sing N N 75  
6PL   C7  H73  sing N N 76  
6PL   C8  H81  sing N N 77  
6PL   C8  H82  sing N N 78  
6PL   C8  H83  sing N N 79  
6PL   C6  H61  sing N N 80  
6PL   C6  H62  sing N N 81  
6PL   C6  H63  sing N N 82  
6PL   O2  C31  sing N N 83  
6PL   C31 O31  doub N N 84  
6PL   C31 C32  sing N N 85  
6PL   C32 C33  sing N N 86  
6PL   C32 H321 sing N N 87  
6PL   C32 H322 sing N N 88  
6PL   C33 C34  sing N N 89  
6PL   C33 H331 sing N N 90  
6PL   C33 H332 sing N N 91  
6PL   C34 C35  sing N N 92  
6PL   C34 H341 sing N N 93  
6PL   C34 H342 sing N N 94  
6PL   C35 C36  sing N N 95  
6PL   C35 H351 sing N N 96  
6PL   C35 H352 sing N N 97  
6PL   C36 C37  sing N N 98  
6PL   C36 H361 sing N N 99  
6PL   C36 H362 sing N N 100 
6PL   C37 C38  sing N N 101 
6PL   C37 H371 sing N N 102 
6PL   C37 H372 sing N N 103 
6PL   C38 C39  sing N N 104 
6PL   C38 H381 sing N N 105 
6PL   C38 H382 sing N N 106 
6PL   C39 C40  sing N N 107 
6PL   C39 H391 sing N N 108 
6PL   C39 H392 sing N N 109 
6PL   C40 C41  sing N N 110 
6PL   C40 H401 sing N N 111 
6PL   C40 H402 sing N N 112 
6PL   C41 C42  sing N N 113 
6PL   C41 H411 sing N N 114 
6PL   C41 H412 sing N N 115 
6PL   C42 C43  sing N N 116 
6PL   C42 H421 sing N N 117 
6PL   C42 H422 sing N N 118 
6PL   C43 C44  sing N N 119 
6PL   C43 H431 sing N N 120 
6PL   C43 H432 sing N N 121 
6PL   C44 C45  sing N N 122 
6PL   C44 H441 sing N N 123 
6PL   C44 H442 sing N N 124 
6PL   C45 C46  sing N N 125 
6PL   C45 H451 sing N N 126 
6PL   C45 H452 sing N N 127 
6PL   C46 C47  sing N N 128 
6PL   C46 H461 sing N N 129 
6PL   C46 H462 sing N N 130 
6PL   C47 C48  sing N N 131 
6PL   C47 H471 sing N N 132 
6PL   C47 H472 sing N N 133 
6PL   C48 H481 sing N N 134 
6PL   C48 H482 sing N N 135 
6PL   C48 H483 sing N N 136 
A1AVC C30 C29  sing N N 137 
A1AVC C29 C28  sing N N 138 
A1AVC C29 C31  sing N N 139 
A1AVC C28 C27  sing N N 140 
A1AVC C21 C22  sing N N 141 
A1AVC C21 C19  sing N N 142 
A1AVC C18 C17  sing N N 143 
A1AVC C18 C19  sing N N 144 
A1AVC C16 C17  sing N N 145 
A1AVC C16 C14  sing N N 146 
A1AVC C27 C26  sing N N 147 
A1AVC C15 C14  sing N N 148 
A1AVC C22 C23  sing N N 149 
A1AVC C14 C13  doub N E 150 
A1AVC C19 C20  sing N N 151 
A1AVC C26 C24  sing N N 152 
A1AVC C23 C24  sing N N 153 
A1AVC C13 C12  sing N N 154 
A1AVC C24 C25  sing N N 155 
A1AVC C12 C11  sing N N 156 
A1AVC O32 C10  sing N N 157 
A1AVC C11 C10  doub Y N 158 
A1AVC C11 C02  sing Y N 159 
A1AVC C01 C02  sing N N 160 
A1AVC C10 C09  sing Y N 161 
A1AVC C02 C03  doub Y N 162 
A1AVC C09 C08  sing Y N 163 
A1AVC C09 C04  doub Y N 164 
A1AVC C03 C04  sing Y N 165 
A1AVC C03 O33  sing N N 166 
A1AVC C08 C07  doub Y N 167 
A1AVC C04 C05  sing Y N 168 
A1AVC C07 C06  sing Y N 169 
A1AVC C05 C06  doub Y N 170 
A1AVC C12 H1   sing N N 171 
A1AVC C12 H2   sing N N 172 
A1AVC C13 H3   sing N N 173 
A1AVC C15 H4   sing N N 174 
A1AVC C15 H5   sing N N 175 
A1AVC C15 H6   sing N N 176 
A1AVC C16 H7   sing N N 177 
A1AVC C16 H8   sing N N 178 
A1AVC C01 H9   sing N N 179 
A1AVC C01 H10  sing N N 180 
A1AVC C01 H11  sing N N 181 
A1AVC C05 H12  sing N N 182 
A1AVC C06 H13  sing N N 183 
A1AVC C07 H14  sing N N 184 
A1AVC C08 H15  sing N N 185 
A1AVC C17 H16  sing N N 186 
A1AVC C17 H17  sing N N 187 
A1AVC C18 H18  sing N N 188 
A1AVC C18 H19  sing N N 189 
A1AVC C19 H20  sing N N 190 
A1AVC C20 H21  sing N N 191 
A1AVC C20 H22  sing N N 192 
A1AVC C20 H23  sing N N 193 
A1AVC C21 H24  sing N N 194 
A1AVC C21 H25  sing N N 195 
A1AVC C22 H26  sing N N 196 
A1AVC C22 H27  sing N N 197 
A1AVC C23 H28  sing N N 198 
A1AVC C23 H29  sing N N 199 
A1AVC C24 H30  sing N N 200 
A1AVC C25 H31  sing N N 201 
A1AVC C25 H32  sing N N 202 
A1AVC C25 H33  sing N N 203 
A1AVC C26 H34  sing N N 204 
A1AVC C26 H35  sing N N 205 
A1AVC C27 H36  sing N N 206 
A1AVC C27 H37  sing N N 207 
A1AVC C28 H38  sing N N 208 
A1AVC C28 H39  sing N N 209 
A1AVC C29 H40  sing N N 210 
A1AVC C30 H41  sing N N 211 
A1AVC C30 H42  sing N N 212 
A1AVC C30 H43  sing N N 213 
A1AVC C31 H44  sing N N 214 
A1AVC C31 H45  sing N N 215 
A1AVC C31 H46  sing N N 216 
A1AVC O32 H47  sing N N 217 
A1AVC O33 H48  sing N N 218 
ALA   N   CA   sing N N 219 
ALA   N   H    sing N N 220 
ALA   N   H2   sing N N 221 
ALA   CA  C    sing N N 222 
ALA   CA  CB   sing N N 223 
ALA   CA  HA   sing N N 224 
ALA   C   O    doub N N 225 
ALA   C   OXT  sing N N 226 
ALA   CB  HB1  sing N N 227 
ALA   CB  HB2  sing N N 228 
ALA   CB  HB3  sing N N 229 
ALA   OXT HXT  sing N N 230 
ARG   N   CA   sing N N 231 
ARG   N   H    sing N N 232 
ARG   N   H2   sing N N 233 
ARG   CA  C    sing N N 234 
ARG   CA  CB   sing N N 235 
ARG   CA  HA   sing N N 236 
ARG   C   O    doub N N 237 
ARG   C   OXT  sing N N 238 
ARG   CB  CG   sing N N 239 
ARG   CB  HB2  sing N N 240 
ARG   CB  HB3  sing N N 241 
ARG   CG  CD   sing N N 242 
ARG   CG  HG2  sing N N 243 
ARG   CG  HG3  sing N N 244 
ARG   CD  NE   sing N N 245 
ARG   CD  HD2  sing N N 246 
ARG   CD  HD3  sing N N 247 
ARG   NE  CZ   sing N N 248 
ARG   NE  HE   sing N N 249 
ARG   CZ  NH1  sing N N 250 
ARG   CZ  NH2  doub N N 251 
ARG   NH1 HH11 sing N N 252 
ARG   NH1 HH12 sing N N 253 
ARG   NH2 HH21 sing N N 254 
ARG   NH2 HH22 sing N N 255 
ARG   OXT HXT  sing N N 256 
ASN   N   CA   sing N N 257 
ASN   N   H    sing N N 258 
ASN   N   H2   sing N N 259 
ASN   CA  C    sing N N 260 
ASN   CA  CB   sing N N 261 
ASN   CA  HA   sing N N 262 
ASN   C   O    doub N N 263 
ASN   C   OXT  sing N N 264 
ASN   CB  CG   sing N N 265 
ASN   CB  HB2  sing N N 266 
ASN   CB  HB3  sing N N 267 
ASN   CG  OD1  doub N N 268 
ASN   CG  ND2  sing N N 269 
ASN   ND2 HD21 sing N N 270 
ASN   ND2 HD22 sing N N 271 
ASN   OXT HXT  sing N N 272 
ASP   N   CA   sing N N 273 
ASP   N   H    sing N N 274 
ASP   N   H2   sing N N 275 
ASP   CA  C    sing N N 276 
ASP   CA  CB   sing N N 277 
ASP   CA  HA   sing N N 278 
ASP   C   O    doub N N 279 
ASP   C   OXT  sing N N 280 
ASP   CB  CG   sing N N 281 
ASP   CB  HB2  sing N N 282 
ASP   CB  HB3  sing N N 283 
ASP   CG  OD1  doub N N 284 
ASP   CG  OD2  sing N N 285 
ASP   OD2 HD2  sing N N 286 
ASP   OXT HXT  sing N N 287 
CYS   N   CA   sing N N 288 
CYS   N   H    sing N N 289 
CYS   N   H2   sing N N 290 
CYS   CA  C    sing N N 291 
CYS   CA  CB   sing N N 292 
CYS   CA  HA   sing N N 293 
CYS   C   O    doub N N 294 
CYS   C   OXT  sing N N 295 
CYS   CB  SG   sing N N 296 
CYS   CB  HB2  sing N N 297 
CYS   CB  HB3  sing N N 298 
CYS   SG  HG   sing N N 299 
CYS   OXT HXT  sing N N 300 
GLN   N   CA   sing N N 301 
GLN   N   H    sing N N 302 
GLN   N   H2   sing N N 303 
GLN   CA  C    sing N N 304 
GLN   CA  CB   sing N N 305 
GLN   CA  HA   sing N N 306 
GLN   C   O    doub N N 307 
GLN   C   OXT  sing N N 308 
GLN   CB  CG   sing N N 309 
GLN   CB  HB2  sing N N 310 
GLN   CB  HB3  sing N N 311 
GLN   CG  CD   sing N N 312 
GLN   CG  HG2  sing N N 313 
GLN   CG  HG3  sing N N 314 
GLN   CD  OE1  doub N N 315 
GLN   CD  NE2  sing N N 316 
GLN   NE2 HE21 sing N N 317 
GLN   NE2 HE22 sing N N 318 
GLN   OXT HXT  sing N N 319 
GLU   N   CA   sing N N 320 
GLU   N   H    sing N N 321 
GLU   N   H2   sing N N 322 
GLU   CA  C    sing N N 323 
GLU   CA  CB   sing N N 324 
GLU   CA  HA   sing N N 325 
GLU   C   O    doub N N 326 
GLU   C   OXT  sing N N 327 
GLU   CB  CG   sing N N 328 
GLU   CB  HB2  sing N N 329 
GLU   CB  HB3  sing N N 330 
GLU   CG  CD   sing N N 331 
GLU   CG  HG2  sing N N 332 
GLU   CG  HG3  sing N N 333 
GLU   CD  OE1  doub N N 334 
GLU   CD  OE2  sing N N 335 
GLU   OE2 HE2  sing N N 336 
GLU   OXT HXT  sing N N 337 
GLY   N   CA   sing N N 338 
GLY   N   H    sing N N 339 
GLY   N   H2   sing N N 340 
GLY   CA  C    sing N N 341 
GLY   CA  HA2  sing N N 342 
GLY   CA  HA3  sing N N 343 
GLY   C   O    doub N N 344 
GLY   C   OXT  sing N N 345 
GLY   OXT HXT  sing N N 346 
HIS   N   CA   sing N N 347 
HIS   N   H    sing N N 348 
HIS   N   H2   sing N N 349 
HIS   CA  C    sing N N 350 
HIS   CA  CB   sing N N 351 
HIS   CA  HA   sing N N 352 
HIS   C   O    doub N N 353 
HIS   C   OXT  sing N N 354 
HIS   CB  CG   sing N N 355 
HIS   CB  HB2  sing N N 356 
HIS   CB  HB3  sing N N 357 
HIS   CG  ND1  sing Y N 358 
HIS   CG  CD2  doub Y N 359 
HIS   ND1 CE1  doub Y N 360 
HIS   ND1 HD1  sing N N 361 
HIS   CD2 NE2  sing Y N 362 
HIS   CD2 HD2  sing N N 363 
HIS   CE1 NE2  sing Y N 364 
HIS   CE1 HE1  sing N N 365 
HIS   NE2 HE2  sing N N 366 
HIS   OXT HXT  sing N N 367 
ILE   N   CA   sing N N 368 
ILE   N   H    sing N N 369 
ILE   N   H2   sing N N 370 
ILE   CA  C    sing N N 371 
ILE   CA  CB   sing N N 372 
ILE   CA  HA   sing N N 373 
ILE   C   O    doub N N 374 
ILE   C   OXT  sing N N 375 
ILE   CB  CG1  sing N N 376 
ILE   CB  CG2  sing N N 377 
ILE   CB  HB   sing N N 378 
ILE   CG1 CD1  sing N N 379 
ILE   CG1 HG12 sing N N 380 
ILE   CG1 HG13 sing N N 381 
ILE   CG2 HG21 sing N N 382 
ILE   CG2 HG22 sing N N 383 
ILE   CG2 HG23 sing N N 384 
ILE   CD1 HD11 sing N N 385 
ILE   CD1 HD12 sing N N 386 
ILE   CD1 HD13 sing N N 387 
ILE   OXT HXT  sing N N 388 
LEU   N   CA   sing N N 389 
LEU   N   H    sing N N 390 
LEU   N   H2   sing N N 391 
LEU   CA  C    sing N N 392 
LEU   CA  CB   sing N N 393 
LEU   CA  HA   sing N N 394 
LEU   C   O    doub N N 395 
LEU   C   OXT  sing N N 396 
LEU   CB  CG   sing N N 397 
LEU   CB  HB2  sing N N 398 
LEU   CB  HB3  sing N N 399 
LEU   CG  CD1  sing N N 400 
LEU   CG  CD2  sing N N 401 
LEU   CG  HG   sing N N 402 
LEU   CD1 HD11 sing N N 403 
LEU   CD1 HD12 sing N N 404 
LEU   CD1 HD13 sing N N 405 
LEU   CD2 HD21 sing N N 406 
LEU   CD2 HD22 sing N N 407 
LEU   CD2 HD23 sing N N 408 
LEU   OXT HXT  sing N N 409 
LYS   N   CA   sing N N 410 
LYS   N   H    sing N N 411 
LYS   N   H2   sing N N 412 
LYS   CA  C    sing N N 413 
LYS   CA  CB   sing N N 414 
LYS   CA  HA   sing N N 415 
LYS   C   O    doub N N 416 
LYS   C   OXT  sing N N 417 
LYS   CB  CG   sing N N 418 
LYS   CB  HB2  sing N N 419 
LYS   CB  HB3  sing N N 420 
LYS   CG  CD   sing N N 421 
LYS   CG  HG2  sing N N 422 
LYS   CG  HG3  sing N N 423 
LYS   CD  CE   sing N N 424 
LYS   CD  HD2  sing N N 425 
LYS   CD  HD3  sing N N 426 
LYS   CE  NZ   sing N N 427 
LYS   CE  HE2  sing N N 428 
LYS   CE  HE3  sing N N 429 
LYS   NZ  HZ1  sing N N 430 
LYS   NZ  HZ2  sing N N 431 
LYS   NZ  HZ3  sing N N 432 
LYS   OXT HXT  sing N N 433 
MET   N   CA   sing N N 434 
MET   N   H    sing N N 435 
MET   N   H2   sing N N 436 
MET   CA  C    sing N N 437 
MET   CA  CB   sing N N 438 
MET   CA  HA   sing N N 439 
MET   C   O    doub N N 440 
MET   C   OXT  sing N N 441 
MET   CB  CG   sing N N 442 
MET   CB  HB2  sing N N 443 
MET   CB  HB3  sing N N 444 
MET   CG  SD   sing N N 445 
MET   CG  HG2  sing N N 446 
MET   CG  HG3  sing N N 447 
MET   SD  CE   sing N N 448 
MET   CE  HE1  sing N N 449 
MET   CE  HE2  sing N N 450 
MET   CE  HE3  sing N N 451 
MET   OXT HXT  sing N N 452 
NAG   C1  C2   sing N N 453 
NAG   C1  O1   sing N N 454 
NAG   C1  O5   sing N N 455 
NAG   C1  H1   sing N N 456 
NAG   C2  C3   sing N N 457 
NAG   C2  N2   sing N N 458 
NAG   C2  H2   sing N N 459 
NAG   C3  C4   sing N N 460 
NAG   C3  O3   sing N N 461 
NAG   C3  H3   sing N N 462 
NAG   C4  C5   sing N N 463 
NAG   C4  O4   sing N N 464 
NAG   C4  H4   sing N N 465 
NAG   C5  C6   sing N N 466 
NAG   C5  O5   sing N N 467 
NAG   C5  H5   sing N N 468 
NAG   C6  O6   sing N N 469 
NAG   C6  H61  sing N N 470 
NAG   C6  H62  sing N N 471 
NAG   C7  C8   sing N N 472 
NAG   C7  N2   sing N N 473 
NAG   C7  O7   doub N N 474 
NAG   C8  H81  sing N N 475 
NAG   C8  H82  sing N N 476 
NAG   C8  H83  sing N N 477 
NAG   N2  HN2  sing N N 478 
NAG   O1  HO1  sing N N 479 
NAG   O3  HO3  sing N N 480 
NAG   O4  HO4  sing N N 481 
NAG   O6  HO6  sing N N 482 
PHE   N   CA   sing N N 483 
PHE   N   H    sing N N 484 
PHE   N   H2   sing N N 485 
PHE   CA  C    sing N N 486 
PHE   CA  CB   sing N N 487 
PHE   CA  HA   sing N N 488 
PHE   C   O    doub N N 489 
PHE   C   OXT  sing N N 490 
PHE   CB  CG   sing N N 491 
PHE   CB  HB2  sing N N 492 
PHE   CB  HB3  sing N N 493 
PHE   CG  CD1  doub Y N 494 
PHE   CG  CD2  sing Y N 495 
PHE   CD1 CE1  sing Y N 496 
PHE   CD1 HD1  sing N N 497 
PHE   CD2 CE2  doub Y N 498 
PHE   CD2 HD2  sing N N 499 
PHE   CE1 CZ   doub Y N 500 
PHE   CE1 HE1  sing N N 501 
PHE   CE2 CZ   sing Y N 502 
PHE   CE2 HE2  sing N N 503 
PHE   CZ  HZ   sing N N 504 
PHE   OXT HXT  sing N N 505 
PRO   N   CA   sing N N 506 
PRO   N   CD   sing N N 507 
PRO   N   H    sing N N 508 
PRO   CA  C    sing N N 509 
PRO   CA  CB   sing N N 510 
PRO   CA  HA   sing N N 511 
PRO   C   O    doub N N 512 
PRO   C   OXT  sing N N 513 
PRO   CB  CG   sing N N 514 
PRO   CB  HB2  sing N N 515 
PRO   CB  HB3  sing N N 516 
PRO   CG  CD   sing N N 517 
PRO   CG  HG2  sing N N 518 
PRO   CG  HG3  sing N N 519 
PRO   CD  HD2  sing N N 520 
PRO   CD  HD3  sing N N 521 
PRO   OXT HXT  sing N N 522 
SER   N   CA   sing N N 523 
SER   N   H    sing N N 524 
SER   N   H2   sing N N 525 
SER   CA  C    sing N N 526 
SER   CA  CB   sing N N 527 
SER   CA  HA   sing N N 528 
SER   C   O    doub N N 529 
SER   C   OXT  sing N N 530 
SER   CB  OG   sing N N 531 
SER   CB  HB2  sing N N 532 
SER   CB  HB3  sing N N 533 
SER   OG  HG   sing N N 534 
SER   OXT HXT  sing N N 535 
THR   N   CA   sing N N 536 
THR   N   H    sing N N 537 
THR   N   H2   sing N N 538 
THR   CA  C    sing N N 539 
THR   CA  CB   sing N N 540 
THR   CA  HA   sing N N 541 
THR   C   O    doub N N 542 
THR   C   OXT  sing N N 543 
THR   CB  OG1  sing N N 544 
THR   CB  CG2  sing N N 545 
THR   CB  HB   sing N N 546 
THR   OG1 HG1  sing N N 547 
THR   CG2 HG21 sing N N 548 
THR   CG2 HG22 sing N N 549 
THR   CG2 HG23 sing N N 550 
THR   OXT HXT  sing N N 551 
TRP   N   CA   sing N N 552 
TRP   N   H    sing N N 553 
TRP   N   H2   sing N N 554 
TRP   CA  C    sing N N 555 
TRP   CA  CB   sing N N 556 
TRP   CA  HA   sing N N 557 
TRP   C   O    doub N N 558 
TRP   C   OXT  sing N N 559 
TRP   CB  CG   sing N N 560 
TRP   CB  HB2  sing N N 561 
TRP   CB  HB3  sing N N 562 
TRP   CG  CD1  doub Y N 563 
TRP   CG  CD2  sing Y N 564 
TRP   CD1 NE1  sing Y N 565 
TRP   CD1 HD1  sing N N 566 
TRP   CD2 CE2  doub Y N 567 
TRP   CD2 CE3  sing Y N 568 
TRP   NE1 CE2  sing Y N 569 
TRP   NE1 HE1  sing N N 570 
TRP   CE2 CZ2  sing Y N 571 
TRP   CE3 CZ3  doub Y N 572 
TRP   CE3 HE3  sing N N 573 
TRP   CZ2 CH2  doub Y N 574 
TRP   CZ2 HZ2  sing N N 575 
TRP   CZ3 CH2  sing Y N 576 
TRP   CZ3 HZ3  sing N N 577 
TRP   CH2 HH2  sing N N 578 
TRP   OXT HXT  sing N N 579 
TYR   N   CA   sing N N 580 
TYR   N   H    sing N N 581 
TYR   N   H2   sing N N 582 
TYR   CA  C    sing N N 583 
TYR   CA  CB   sing N N 584 
TYR   CA  HA   sing N N 585 
TYR   C   O    doub N N 586 
TYR   C   OXT  sing N N 587 
TYR   CB  CG   sing N N 588 
TYR   CB  HB2  sing N N 589 
TYR   CB  HB3  sing N N 590 
TYR   CG  CD1  doub Y N 591 
TYR   CG  CD2  sing Y N 592 
TYR   CD1 CE1  sing Y N 593 
TYR   CD1 HD1  sing N N 594 
TYR   CD2 CE2  doub Y N 595 
TYR   CD2 HD2  sing N N 596 
TYR   CE1 CZ   doub Y N 597 
TYR   CE1 HE1  sing N N 598 
TYR   CE2 CZ   sing Y N 599 
TYR   CE2 HE2  sing N N 600 
TYR   CZ  OH   sing N N 601 
TYR   OH  HH   sing N N 602 
TYR   OXT HXT  sing N N 603 
VAL   N   CA   sing N N 604 
VAL   N   H    sing N N 605 
VAL   N   H2   sing N N 606 
VAL   CA  C    sing N N 607 
VAL   CA  CB   sing N N 608 
VAL   CA  HA   sing N N 609 
VAL   C   O    doub N N 610 
VAL   C   OXT  sing N N 611 
VAL   CB  CG1  sing N N 612 
VAL   CB  CG2  sing N N 613 
VAL   CB  HB   sing N N 614 
VAL   CG1 HG11 sing N N 615 
VAL   CG1 HG12 sing N N 616 
VAL   CG1 HG13 sing N N 617 
VAL   CG2 HG21 sing N N 618 
VAL   CG2 HG22 sing N N 619 
VAL   CG2 HG23 sing N N 620 
VAL   OXT HXT  sing N N 621 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-20 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9BVR 
_em_admin.last_update        2025-03-26 
_em_admin.map_release_date   2025-01-22 
_em_admin.title              
;Vitamin K-dependent gamma-carboxylase with factor IX propeptide and partially carboxylated glutamate-rich region and with vitamin K hydroquinone and calcium
;
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 150   mM NaCl       1 'Sodium chloride'        
1 20    mM C8H18N2O4S 2 HEPES                    
1 0.005 %  C56H92O25  3 Glyco-diosgenin          
1 0.055 mM C31H48O2   4 'Vitamin K hydroquinone' 
1 1.84  mM NaHCO3     5 'Sodium bicarbonate'     
1 5     mM CaCl2      6 'Calcium chloride'       
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.11 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 HEK293 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              'pEG BacMam' 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         54.8 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     4992 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.21.1_5286: 
'IMAGE ACQUISITION'             ? 2  1 ? 1 ?      ?            
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?            
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?            
CLASSIFICATION                  ? 5  1 1 1 ?      ?            
MASKING                         ? 6  1 1 1 ?      ?            
RECONSTRUCTION                  ? 7  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?            
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?            
'CTF CORRECTION'                ? 10 1 1 1 ?      ?            
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?            
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?            
'MODEL FITTING'                 ? 13 1 1 1 ?      ?            
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?            
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?            
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?            
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?            
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?            
OTHER                           ? 19 1 1 1 ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)'             'United States' HL121718 1 
'American Heart Association'                                                                      'United States' 
'Established Investigator Award' 2 
'American Heart Association'                                                                      'United States' 
'Collaborative Sciences Award'   3 
'W. M. Keck Foundation'                                                                           'United States' 
'Forefront of Science Award'     4 
'Childrens Discovery Institute of Washington University and St. Louis Childrens Hospital'         'United States' 'MCII 2020-854' 
5 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' AI158500 6 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)'        'United States' GM131008 7 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
3 NAG 1 n 
3 NAG 2 n 
# 
_atom_sites.entry_id                    9BVR 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ASP   A 1 5   ? 105.928 131.380 142.050 1.00 124.35 ? 31  ASP   A N   1 
ATOM   2    C CA  . ASP   A 1 5   ? 105.251 132.347 142.906 1.00 124.60 ? 31  ASP   A CA  1 
ATOM   3    C C   . ASP   A 1 5   ? 105.806 132.344 144.331 1.00 114.35 ? 31  ASP   A C   1 
ATOM   4    O O   . ASP   A 1 5   ? 105.617 133.310 145.071 1.00 106.03 ? 31  ASP   A O   1 
ATOM   5    C CB  . ASP   A 1 5   ? 103.747 132.066 142.941 1.00 123.90 ? 31  ASP   A CB  1 
ATOM   6    C CG  . ASP   A 1 5   ? 103.108 132.135 141.568 1.00 125.86 ? 31  ASP   A CG  1 
ATOM   7    O OD1 . ASP   A 1 5   ? 103.640 132.856 140.698 1.00 130.02 ? 31  ASP   A OD1 1 
ATOM   8    O OD2 . ASP   A 1 5   ? 102.072 131.469 141.359 1.00 124.47 ? 31  ASP   A OD2 1 
ATOM   9    N N   . SER   A 1 6   ? 106.483 131.260 144.713 1.00 112.62 ? 32  SER   A N   1 
ATOM   10   C CA  . SER   A 1 6   ? 107.032 131.161 146.059 1.00 109.04 ? 32  SER   A CA  1 
ATOM   11   C C   . SER   A 1 6   ? 108.081 132.241 146.290 1.00 106.59 ? 32  SER   A C   1 
ATOM   12   O O   . SER   A 1 6   ? 108.843 132.596 145.386 1.00 109.00 ? 32  SER   A O   1 
ATOM   13   C CB  . SER   A 1 6   ? 107.644 129.779 146.282 1.00 100.51 ? 32  SER   A CB  1 
ATOM   14   O OG  . SER   A 1 6   ? 106.677 128.760 146.098 1.00 103.49 ? 32  SER   A OG  1 
ATOM   15   N N   . ARG   A 1 7   ? 108.110 132.771 147.515 1.00 101.75 ? 33  ARG   A N   1 
ATOM   16   C CA  . ARG   A 1 7   ? 109.047 133.842 147.834 1.00 102.99 ? 33  ARG   A CA  1 
ATOM   17   C C   . ARG   A 1 7   ? 110.493 133.381 147.718 1.00 99.78  ? 33  ARG   A C   1 
ATOM   18   O O   . ARG   A 1 7   ? 111.368 134.180 147.365 1.00 100.62 ? 33  ARG   A O   1 
ATOM   19   C CB  . ARG   A 1 7   ? 108.773 134.380 149.238 1.00 107.82 ? 33  ARG   A CB  1 
ATOM   20   C CG  . ARG   A 1 7   ? 107.470 135.148 149.353 1.00 111.98 ? 33  ARG   A CG  1 
ATOM   21   C CD  . ARG   A 1 7   ? 107.216 135.597 150.782 1.00 125.00 ? 33  ARG   A CD  1 
ATOM   22   N NE  . ARG   A 1 7   ? 105.954 136.317 150.912 1.00 133.95 ? 33  ARG   A NE  1 
ATOM   23   C CZ  . ARG   A 1 7   ? 105.471 136.804 152.048 1.00 135.57 ? 33  ARG   A CZ  1 
ATOM   24   N NH1 . ARG   A 1 7   ? 106.120 136.669 153.196 1.00 135.04 ? 33  ARG   A NH1 1 
ATOM   25   N NH2 . ARG   A 1 7   ? 104.306 137.443 152.035 1.00 135.22 ? 33  ARG   A NH2 1 
ATOM   26   N N   . ILE   A 1 8   ? 110.769 132.110 148.018 1.00 92.36  ? 34  ILE   A N   1 
ATOM   27   C CA  . ILE   A 1 8   ? 112.130 131.597 147.872 1.00 91.00  ? 34  ILE   A CA  1 
ATOM   28   C C   . ILE   A 1 8   ? 112.554 131.660 146.410 1.00 88.65  ? 34  ILE   A C   1 
ATOM   29   O O   . ILE   A 1 8   ? 113.653 132.122 146.079 1.00 87.72  ? 34  ILE   A O   1 
ATOM   30   C CB  . ILE   A 1 8   ? 112.232 130.166 148.438 1.00 92.27  ? 34  ILE   A CB  1 
ATOM   31   C CG1 . ILE   A 1 8   ? 112.306 130.187 149.974 1.00 94.76  ? 34  ILE   A CG1 1 
ATOM   32   C CG2 . ILE   A 1 8   ? 113.451 129.421 147.865 1.00 91.11  ? 34  ILE   A CG2 1 
ATOM   33   C CD1 . ILE   A 1 8   ? 111.025 130.604 150.672 1.00 94.56  ? 34  ILE   A CD1 1 
ATOM   34   N N   . GLY   A 1 9   ? 111.680 131.200 145.514 1.00 90.72  ? 35  GLY   A N   1 
ATOM   35   C CA  . GLY   A 1 9   ? 111.972 131.290 144.095 1.00 88.15  ? 35  GLY   A CA  1 
ATOM   36   C C   . GLY   A 1 9   ? 112.127 132.721 143.623 1.00 85.37  ? 35  GLY   A C   1 
ATOM   37   O O   . GLY   A 1 9   ? 112.974 133.017 142.778 1.00 90.29  ? 35  GLY   A O   1 
ATOM   38   N N   . LYS   A 1 10  ? 111.305 133.627 144.151 1.00 81.81  ? 36  LYS   A N   1 
ATOM   39   C CA  . LYS   A 1 10  ? 111.382 135.019 143.722 1.00 78.81  ? 36  LYS   A CA  1 
ATOM   40   C C   . LYS   A 1 10  ? 112.698 135.653 144.154 1.00 86.00  ? 36  LYS   A C   1 
ATOM   41   O O   . LYS   A 1 10  ? 113.365 136.324 143.359 1.00 91.74  ? 36  LYS   A O   1 
ATOM   42   C CB  . LYS   A 1 10  ? 110.194 135.801 144.276 1.00 86.80  ? 36  LYS   A CB  1 
ATOM   43   C CG  . LYS   A 1 10  ? 110.053 137.205 143.695 1.00 91.83  ? 36  LYS   A CG  1 
ATOM   44   C CD  . LYS   A 1 10  ? 108.785 137.917 144.174 1.00 97.51  ? 36  LYS   A CD  1 
ATOM   45   C CE  . LYS   A 1 10  ? 107.500 137.309 143.609 1.00 95.75  ? 36  LYS   A CE  1 
ATOM   46   N NZ  . LYS   A 1 10  ? 107.482 137.242 142.120 1.00 93.30  ? 36  LYS   A NZ  1 
ATOM   47   N N   . LEU   A 1 11  ? 113.088 135.453 145.414 1.00 87.81  ? 37  LEU   A N   1 
ATOM   48   C CA  . LEU   A 1 11  ? 114.314 136.066 145.911 1.00 87.86  ? 37  LEU   A CA  1 
ATOM   49   C C   . LEU   A 1 11  ? 115.548 135.445 145.265 1.00 83.90  ? 37  LEU   A C   1 
ATOM   50   O O   . LEU   A 1 11  ? 116.415 136.160 144.750 1.00 81.28  ? 37  LEU   A O   1 
ATOM   51   C CB  . LEU   A 1 11  ? 114.386 135.937 147.433 1.00 87.23  ? 37  LEU   A CB  1 
ATOM   52   C CG  . LEU   A 1 11  ? 113.323 136.669 148.258 1.00 91.34  ? 37  LEU   A CG  1 
ATOM   53   C CD1 . LEU   A 1 11  ? 113.490 136.333 149.730 1.00 90.94  ? 37  LEU   A CD1 1 
ATOM   54   C CD2 . LEU   A 1 11  ? 113.388 138.173 148.046 1.00 90.53  ? 37  LEU   A CD2 1 
ATOM   55   N N   . LEU   A 1 12  ? 115.646 134.115 145.280 1.00 85.52  ? 38  LEU   A N   1 
ATOM   56   C CA  . LEU   A 1 12  ? 116.835 133.426 144.796 1.00 84.66  ? 38  LEU   A CA  1 
ATOM   57   C C   . LEU   A 1 12  ? 116.766 133.050 143.320 1.00 85.60  ? 38  LEU   A C   1 
ATOM   58   O O   . LEU   A 1 12  ? 117.781 132.620 142.763 1.00 86.14  ? 38  LEU   A O   1 
ATOM   59   C CB  . LEU   A 1 12  ? 117.082 132.159 145.622 1.00 85.56  ? 38  LEU   A CB  1 
ATOM   60   C CG  . LEU   A 1 12  ? 117.672 132.339 147.024 1.00 85.43  ? 38  LEU   A CG  1 
ATOM   61   C CD1 . LEU   A 1 12  ? 116.675 132.966 147.980 1.00 85.88  ? 38  LEU   A CD1 1 
ATOM   62   C CD2 . LEU   A 1 12  ? 118.164 131.004 147.563 1.00 89.67  ? 38  LEU   A CD2 1 
ATOM   63   N N   . GLY   A 1 13  ? 115.610 133.194 142.676 1.00 85.46  ? 39  GLY   A N   1 
ATOM   64   C CA  . GLY   A 1 13  ? 115.476 132.890 141.267 1.00 76.56  ? 39  GLY   A CA  1 
ATOM   65   C C   . GLY   A 1 13  ? 115.254 131.434 140.926 1.00 73.08  ? 39  GLY   A C   1 
ATOM   66   O O   . GLY   A 1 13  ? 115.176 131.105 139.736 1.00 70.13  ? 39  GLY   A O   1 
ATOM   67   N N   . PHE   A 1 14  ? 115.148 130.550 141.915 1.00 80.43  ? 40  PHE   A N   1 
ATOM   68   C CA  . PHE   A 1 14  ? 114.940 129.136 141.641 1.00 82.97  ? 40  PHE   A CA  1 
ATOM   69   C C   . PHE   A 1 14  ? 114.226 128.491 142.819 1.00 92.43  ? 40  PHE   A C   1 
ATOM   70   O O   . PHE   A 1 14  ? 114.386 128.905 143.971 1.00 99.01  ? 40  PHE   A O   1 
ATOM   71   C CB  . PHE   A 1 14  ? 116.268 128.419 141.370 1.00 85.81  ? 40  PHE   A CB  1 
ATOM   72   C CG  . PHE   A 1 14  ? 117.113 128.218 142.596 1.00 89.68  ? 40  PHE   A CG  1 
ATOM   73   C CD1 . PHE   A 1 14  ? 117.861 129.259 143.118 1.00 85.05  ? 40  PHE   A CD1 1 
ATOM   74   C CD2 . PHE   A 1 14  ? 117.168 126.983 143.217 1.00 94.12  ? 40  PHE   A CD2 1 
ATOM   75   C CE1 . PHE   A 1 14  ? 118.641 129.072 144.241 1.00 87.66  ? 40  PHE   A CE1 1 
ATOM   76   C CE2 . PHE   A 1 14  ? 117.946 126.792 144.340 1.00 95.63  ? 40  PHE   A CE2 1 
ATOM   77   C CZ  . PHE   A 1 14  ? 118.684 127.837 144.852 1.00 94.48  ? 40  PHE   A CZ  1 
ATOM   78   N N   . GLU   A 1 15  ? 113.452 127.456 142.515 1.00 88.44  ? 41  GLU   A N   1 
ATOM   79   C CA  . GLU   A 1 15  ? 112.757 126.664 143.517 1.00 92.47  ? 41  GLU   A CA  1 
ATOM   80   C C   . GLU   A 1 15  ? 113.624 125.479 143.925 1.00 95.68  ? 41  GLU   A C   1 
ATOM   81   O O   . GLU   A 1 15  ? 114.541 125.074 143.206 1.00 97.34  ? 41  GLU   A O   1 
ATOM   82   C CB  . GLU   A 1 15  ? 111.409 126.166 142.986 1.00 92.34  ? 41  GLU   A CB  1 
ATOM   83   C CG  . GLU   A 1 15  ? 110.460 127.259 142.518 1.00 94.28  ? 41  GLU   A CG  1 
ATOM   84   C CD  . GLU   A 1 15  ? 109.977 128.148 143.647 1.00 110.88 ? 41  GLU   A CD  1 
ATOM   85   O OE1 . GLU   A 1 15  ? 110.204 127.800 144.825 1.00 115.42 ? 41  GLU   A OE1 1 
ATOM   86   O OE2 . GLU   A 1 15  ? 109.364 129.197 143.355 1.00 110.75 ? 41  GLU   A OE2 1 
ATOM   87   N N   . TRP   A 1 16  ? 113.324 124.924 145.101 1.00 95.60  ? 42  TRP   A N   1 
ATOM   88   C CA  . TRP   A 1 16  ? 114.097 123.786 145.587 1.00 100.21 ? 42  TRP   A CA  1 
ATOM   89   C C   . TRP   A 1 16  ? 113.921 122.567 144.693 1.00 94.69  ? 42  TRP   A C   1 
ATOM   90   O O   . TRP   A 1 16  ? 114.836 121.741 144.586 1.00 93.14  ? 42  TRP   A O   1 
ATOM   91   C CB  . TRP   A 1 16  ? 113.695 123.445 147.022 1.00 105.17 ? 42  TRP   A CB  1 
ATOM   92   C CG  . TRP   A 1 16  ? 113.886 124.568 147.993 1.00 107.98 ? 42  TRP   A CG  1 
ATOM   93   C CD1 . TRP   A 1 16  ? 112.921 125.174 148.742 1.00 107.97 ? 42  TRP   A CD1 1 
ATOM   94   C CD2 . TRP   A 1 16  ? 115.118 125.221 148.321 1.00 105.37 ? 42  TRP   A CD2 1 
ATOM   95   N NE1 . TRP   A 1 16  ? 113.475 126.162 149.517 1.00 106.51 ? 42  TRP   A NE1 1 
ATOM   96   C CE2 . TRP   A 1 16  ? 114.823 126.211 149.278 1.00 106.54 ? 42  TRP   A CE2 1 
ATOM   97   C CE3 . TRP   A 1 16  ? 116.441 125.064 147.900 1.00 98.77  ? 42  TRP   A CE3 1 
ATOM   98   C CZ2 . TRP   A 1 16  ? 115.802 127.041 149.818 1.00 102.78 ? 42  TRP   A CZ2 1 
ATOM   99   C CZ3 . TRP   A 1 16  ? 117.411 125.888 148.439 1.00 97.02  ? 42  TRP   A CZ3 1 
ATOM   100  C CH2 . TRP   A 1 16  ? 117.086 126.863 149.387 1.00 94.72  ? 42  TRP   A CH2 1 
ATOM   101  N N   . THR   A 1 17  ? 112.763 122.439 144.040 1.00 88.18  ? 43  THR   A N   1 
ATOM   102  C CA  . THR   A 1 17  ? 112.511 121.288 143.180 1.00 86.69  ? 43  THR   A CA  1 
ATOM   103  C C   . THR   A 1 17  ? 113.505 121.189 142.030 1.00 90.89  ? 43  THR   A C   1 
ATOM   104  O O   . THR   A 1 17  ? 113.729 120.089 141.515 1.00 93.67  ? 43  THR   A O   1 
ATOM   105  C CB  . THR   A 1 17  ? 111.081 121.332 142.622 1.00 90.09  ? 43  THR   A CB  1 
ATOM   106  O OG1 . THR   A 1 17  ? 110.885 120.234 141.723 1.00 90.14  ? 43  THR   A OG1 1 
ATOM   107  C CG2 . THR   A 1 17  ? 110.790 122.646 141.882 1.00 89.26  ? 43  THR   A CG2 1 
ATOM   108  N N   . ASP   A 1 18  ? 114.105 122.307 141.616 1.00 96.54  ? 44  ASP   A N   1 
ATOM   109  C CA  . ASP   A 1 18  ? 115.113 122.259 140.565 1.00 96.33  ? 44  ASP   A CA  1 
ATOM   110  C C   . ASP   A 1 18  ? 116.378 121.531 141.003 1.00 94.50  ? 44  ASP   A C   1 
ATOM   111  O O   . ASP   A 1 18  ? 117.134 121.067 140.142 1.00 92.33  ? 44  ASP   A O   1 
ATOM   112  C CB  . ASP   A 1 18  ? 115.466 123.676 140.111 1.00 91.41  ? 44  ASP   A CB  1 
ATOM   113  C CG  . ASP   A 1 18  ? 114.318 124.364 139.402 1.00 93.47  ? 44  ASP   A CG  1 
ATOM   114  O OD1 . ASP   A 1 18  ? 113.599 123.690 138.635 1.00 95.10  ? 44  ASP   A OD1 1 
ATOM   115  O OD2 . ASP   A 1 18  ? 114.132 125.581 139.613 1.00 93.09  ? 44  ASP   A OD2 1 
ATOM   116  N N   . LEU   A 1 19  ? 116.623 121.415 142.308 1.00 91.90  ? 45  LEU   A N   1 
ATOM   117  C CA  . LEU   A 1 19  ? 117.790 120.716 142.829 1.00 92.52  ? 45  LEU   A CA  1 
ATOM   118  C C   . LEU   A 1 19  ? 117.505 119.257 143.169 1.00 92.26  ? 45  LEU   A C   1 
ATOM   119  O O   . LEU   A 1 19  ? 118.386 118.578 143.706 1.00 94.12  ? 45  LEU   A O   1 
ATOM   120  C CB  . LEU   A 1 19  ? 118.319 121.432 144.076 1.00 92.12  ? 45  LEU   A CB  1 
ATOM   121  C CG  . LEU   A 1 19  ? 118.622 122.927 143.963 1.00 94.49  ? 45  LEU   A CG  1 
ATOM   122  C CD1 . LEU   A 1 19  ? 119.125 123.452 145.297 1.00 93.92  ? 45  LEU   A CD1 1 
ATOM   123  C CD2 . LEU   A 1 19  ? 119.630 123.211 142.862 1.00 93.36  ? 45  LEU   A CD2 1 
ATOM   124  N N   . SER   A 1 20  ? 116.299 118.762 142.878 1.00 88.14  ? 46  SER   A N   1 
ATOM   125  C CA  . SER   A 1 20  ? 115.951 117.396 143.254 1.00 85.09  ? 46  SER   A CA  1 
ATOM   126  C C   . SER   A 1 20  ? 116.799 116.378 142.504 1.00 78.78  ? 46  SER   A C   1 
ATOM   127  O O   . SER   A 1 20  ? 117.234 115.377 143.086 1.00 86.18  ? 46  SER   A O   1 
ATOM   128  C CB  . SER   A 1 20  ? 114.466 117.143 142.998 1.00 92.27  ? 46  SER   A CB  1 
ATOM   129  O OG  . SER   A 1 20  ? 114.150 117.306 141.628 1.00 93.80  ? 46  SER   A OG  1 
ATOM   130  N N   . SER   A 1 21  ? 117.043 116.614 141.216 1.00 76.43  ? 47  SER   A N   1 
ATOM   131  C CA  . SER   A 1 21  ? 117.749 115.674 140.357 1.00 81.28  ? 47  SER   A CA  1 
ATOM   132  C C   . SER   A 1 21  ? 118.817 116.403 139.556 1.00 79.44  ? 47  SER   A C   1 
ATOM   133  O O   . SER   A 1 21  ? 118.810 117.631 139.439 1.00 86.16  ? 47  SER   A O   1 
ATOM   134  C CB  . SER   A 1 21  ? 116.787 114.954 139.405 1.00 86.47  ? 47  SER   A CB  1 
ATOM   135  O OG  . SER   A 1 21  ? 117.480 114.032 138.583 1.00 85.62  ? 47  SER   A OG  1 
ATOM   136  N N   . TRP   A 1 22  ? 119.748 115.619 139.009 1.00 67.34  ? 48  TRP   A N   1 
ATOM   137  C CA  . TRP   A 1 22  ? 120.834 116.191 138.220 1.00 70.13  ? 48  TRP   A CA  1 
ATOM   138  C C   . TRP   A 1 22  ? 120.309 116.859 136.958 1.00 75.86  ? 48  TRP   A C   1 
ATOM   139  O O   . TRP   A 1 22  ? 120.792 117.929 136.564 1.00 80.26  ? 48  TRP   A O   1 
ATOM   140  C CB  . TRP   A 1 22  ? 121.847 115.106 137.865 1.00 66.32  ? 48  TRP   A CB  1 
ATOM   141  C CG  . TRP   A 1 22  ? 122.890 115.557 136.896 1.00 61.51  ? 48  TRP   A CG  1 
ATOM   142  C CD1 . TRP   A 1 22  ? 122.959 115.252 135.573 1.00 63.76  ? 48  TRP   A CD1 1 
ATOM   143  C CD2 . TRP   A 1 22  ? 124.017 116.396 137.174 1.00 60.39  ? 48  TRP   A CD2 1 
ATOM   144  N NE1 . TRP   A 1 22  ? 124.058 115.846 135.006 1.00 68.15  ? 48  TRP   A NE1 1 
ATOM   145  C CE2 . TRP   A 1 22  ? 124.724 116.555 135.969 1.00 59.65  ? 48  TRP   A CE2 1 
ATOM   146  C CE3 . TRP   A 1 22  ? 124.495 117.029 138.324 1.00 68.80  ? 48  TRP   A CE3 1 
ATOM   147  C CZ2 . TRP   A 1 22  ? 125.883 117.318 135.880 1.00 62.64  ? 48  TRP   A CZ2 1 
ATOM   148  C CZ3 . TRP   A 1 22  ? 125.645 117.787 138.233 1.00 69.40  ? 48  TRP   A CZ3 1 
ATOM   149  C CH2 . TRP   A 1 22  ? 126.326 117.925 137.020 1.00 66.16  ? 48  TRP   A CH2 1 
ATOM   150  N N   . ARG   A 1 23  ? 119.329 116.235 136.301 1.00 73.58  ? 49  ARG   A N   1 
ATOM   151  C CA  . ARG   A 1 23  ? 118.793 116.792 135.065 1.00 73.60  ? 49  ARG   A CA  1 
ATOM   152  C C   . ARG   A 1 23  ? 118.154 118.153 135.309 1.00 76.18  ? 49  ARG   A C   1 
ATOM   153  O O   . ARG   A 1 23  ? 118.347 119.091 134.526 1.00 81.13  ? 49  ARG   A O   1 
ATOM   154  C CB  . ARG   A 1 23  ? 117.784 115.818 134.458 1.00 78.83  ? 49  ARG   A CB  1 
ATOM   155  C CG  . ARG   A 1 23  ? 117.277 116.201 133.077 1.00 84.81  ? 49  ARG   A CG  1 
ATOM   156  C CD  . ARG   A 1 23  ? 116.320 115.150 132.544 1.00 88.96  ? 49  ARG   A CD  1 
ATOM   157  N NE  . ARG   A 1 23  ? 115.729 115.531 131.267 1.00 98.31  ? 49  ARG   A NE  1 
ATOM   158  C CZ  . ARG   A 1 23  ? 114.806 114.829 130.621 1.00 104.34 ? 49  ARG   A CZ  1 
ATOM   159  N NH1 . ARG   A 1 23  ? 114.333 113.689 131.103 1.00 102.63 ? 49  ARG   A NH1 1 
ATOM   160  N NH2 . ARG   A 1 23  ? 114.342 115.282 129.460 1.00 105.24 ? 49  ARG   A NH2 1 
ATOM   161  N N   . ARG   A 1 24  ? 117.398 118.285 136.400 1.00 72.75  ? 50  ARG   A N   1 
ATOM   162  C CA  . ARG   A 1 24  ? 116.772 119.567 136.700 1.00 77.63  ? 50  ARG   A CA  1 
ATOM   163  C C   . ARG   A 1 24  ? 117.811 120.608 137.099 1.00 77.67  ? 50  ARG   A C   1 
ATOM   164  O O   . ARG   A 1 24  ? 117.649 121.795 136.798 1.00 81.70  ? 50  ARG   A O   1 
ATOM   165  C CB  . ARG   A 1 24  ? 115.720 119.391 137.793 1.00 82.61  ? 50  ARG   A CB  1 
ATOM   166  C CG  . ARG   A 1 24  ? 114.551 118.520 137.354 1.00 90.53  ? 50  ARG   A CG  1 
ATOM   167  C CD  . ARG   A 1 24  ? 113.485 118.409 138.427 1.00 95.72  ? 50  ARG   A CD  1 
ATOM   168  N NE  . ARG   A 1 24  ? 112.389 117.539 138.014 1.00 98.28  ? 50  ARG   A NE  1 
ATOM   169  C CZ  . ARG   A 1 24  ? 111.324 117.254 138.753 1.00 99.10  ? 50  ARG   A CZ  1 
ATOM   170  N NH1 . ARG   A 1 24  ? 111.165 117.754 139.969 1.00 95.83  ? 50  ARG   A NH1 1 
ATOM   171  N NH2 . ARG   A 1 24  ? 110.393 116.442 138.260 1.00 101.82 ? 50  ARG   A NH2 1 
ATOM   172  N N   . LEU   A 1 25  ? 118.889 120.186 137.763 1.00 73.88  ? 51  LEU   A N   1 
ATOM   173  C CA  . LEU   A 1 25  ? 119.972 121.117 138.068 1.00 73.09  ? 51  LEU   A CA  1 
ATOM   174  C C   . LEU   A 1 25  ? 120.621 121.641 136.793 1.00 70.03  ? 51  LEU   A C   1 
ATOM   175  O O   . LEU   A 1 25  ? 120.901 122.841 136.674 1.00 72.77  ? 51  LEU   A O   1 
ATOM   176  C CB  . LEU   A 1 25  ? 121.010 120.431 138.958 1.00 72.97  ? 51  LEU   A CB  1 
ATOM   177  C CG  . LEU   A 1 25  ? 122.264 121.222 139.340 1.00 76.73  ? 51  LEU   A CG  1 
ATOM   178  C CD1 . LEU   A 1 25  ? 121.900 122.506 140.054 1.00 76.01  ? 51  LEU   A CD1 1 
ATOM   179  C CD2 . LEU   A 1 25  ? 123.171 120.370 140.208 1.00 80.65  ? 51  LEU   A CD2 1 
ATOM   180  N N   . VAL   A 1 26  ? 120.864 120.755 135.825 1.00 63.10  ? 52  VAL   A N   1 
ATOM   181  C CA  . VAL   A 1 26  ? 121.450 121.184 134.560 1.00 59.18  ? 52  VAL   A CA  1 
ATOM   182  C C   . VAL   A 1 26  ? 120.496 122.117 133.826 1.00 65.26  ? 52  VAL   A C   1 
ATOM   183  O O   . VAL   A 1 26  ? 120.914 123.126 133.243 1.00 74.09  ? 52  VAL   A O   1 
ATOM   184  C CB  . VAL   A 1 26  ? 121.824 119.960 133.703 1.00 63.12  ? 52  VAL   A CB  1 
ATOM   185  C CG1 . VAL   A 1 26  ? 122.229 120.383 132.303 1.00 67.28  ? 52  VAL   A CG1 1 
ATOM   186  C CG2 . VAL   A 1 26  ? 122.949 119.176 134.359 1.00 68.45  ? 52  VAL   A CG2 1 
ATOM   187  N N   . THR   A 1 27  ? 119.200 121.798 133.845 1.00 61.34  ? 53  THR   A N   1 
ATOM   188  C CA  . THR   A 1 27  ? 118.220 122.663 133.195 1.00 62.35  ? 53  THR   A CA  1 
ATOM   189  C C   . THR   A 1 27  ? 118.175 124.038 133.853 1.00 64.03  ? 53  THR   A C   1 
ATOM   190  O O   . THR   A 1 27  ? 118.043 125.057 133.166 1.00 68.90  ? 53  THR   A O   1 
ATOM   191  C CB  . THR   A 1 27  ? 116.841 122.007 133.222 1.00 64.25  ? 53  THR   A CB  1 
ATOM   192  O OG1 . THR   A 1 27  ? 116.853 120.837 132.394 1.00 64.74  ? 53  THR   A OG1 1 
ATOM   193  C CG2 . THR   A 1 27  ? 115.772 122.964 132.718 1.00 69.71  ? 53  THR   A CG2 1 
ATOM   194  N N   . LEU   A 1 28  ? 118.277 124.087 135.181 1.00 64.53  ? 54  LEU   A N   1 
ATOM   195  C CA  . LEU   A 1 28  ? 118.297 125.373 135.870 1.00 65.97  ? 54  LEU   A CA  1 
ATOM   196  C C   . LEU   A 1 28  ? 119.538 126.172 135.503 1.00 64.98  ? 54  LEU   A C   1 
ATOM   197  O O   . LEU   A 1 28  ? 119.450 127.372 135.218 1.00 66.95  ? 54  LEU   A O   1 
ATOM   198  C CB  . LEU   A 1 28  ? 118.225 125.161 137.383 1.00 67.71  ? 54  LEU   A CB  1 
ATOM   199  C CG  . LEU   A 1 28  ? 118.371 126.394 138.281 1.00 69.80  ? 54  LEU   A CG  1 
ATOM   200  C CD1 . LEU   A 1 28  ? 117.353 127.457 137.920 1.00 74.73  ? 54  LEU   A CD1 1 
ATOM   201  C CD2 . LEU   A 1 28  ? 118.226 126.004 139.738 1.00 80.32  ? 54  LEU   A CD2 1 
ATOM   202  N N   . LEU   A 1 29  ? 120.704 125.527 135.495 1.00 63.81  ? 55  LEU   A N   1 
ATOM   203  C CA  . LEU   A 1 29  ? 121.942 126.236 135.195 1.00 65.51  ? 55  LEU   A CA  1 
ATOM   204  C C   . LEU   A 1 29  ? 122.133 126.515 133.710 1.00 63.93  ? 55  LEU   A C   1 
ATOM   205  O O   . LEU   A 1 29  ? 123.097 127.202 133.355 1.00 66.98  ? 55  LEU   A O   1 
ATOM   206  C CB  . LEU   A 1 29  ? 123.148 125.446 135.715 1.00 69.41  ? 55  LEU   A CB  1 
ATOM   207  C CG  . LEU   A 1 29  ? 123.429 125.463 137.221 1.00 71.34  ? 55  LEU   A CG  1 
ATOM   208  C CD1 . LEU   A 1 29  ? 124.590 124.540 137.532 1.00 71.36  ? 55  LEU   A CD1 1 
ATOM   209  C CD2 . LEU   A 1 29  ? 123.721 126.865 137.728 1.00 67.70  ? 55  LEU   A CD2 1 
ATOM   210  N N   . ASN   A 1 30  ? 121.255 126.001 132.840 1.00 59.82  ? 56  ASN   A N   1 
ATOM   211  C CA  . ASN   A 1 30  ? 121.332 126.244 131.403 1.00 54.33  ? 56  ASN   A CA  1 
ATOM   212  C C   . ASN   A 1 30  ? 120.041 126.858 130.871 1.00 58.48  ? 56  ASN   A C   1 
ATOM   213  O O   . ASN   A 1 30  ? 119.671 126.631 129.715 1.00 67.92  ? 56  ASN   A O   1 
ATOM   214  C CB  . ASN   A 1 30  ? 121.664 124.952 130.660 1.00 50.76  ? 56  ASN   A CB  1 
ATOM   215  C CG  . ASN   A 1 30  ? 123.057 124.462 130.958 1.00 54.12  ? 56  ASN   A CG  1 
ATOM   216  O OD1 . ASN   A 1 30  ? 123.979 124.665 130.172 1.00 58.54  ? 56  ASN   A OD1 1 
ATOM   217  N ND2 . ASN   A 1 30  ? 123.224 123.824 132.107 1.00 65.03  ? 56  ASN   A ND2 1 
ATOM   218  N N   . ARG   A 1 31  ? 119.348 127.645 131.693 1.00 54.16  ? 57  ARG   A N   1 
ATOM   219  C CA  . ARG   A 1 31  ? 118.145 128.317 131.229 1.00 53.66  ? 57  ARG   A CA  1 
ATOM   220  C C   . ARG   A 1 31  ? 118.510 129.562 130.416 1.00 51.01  ? 57  ARG   A C   1 
ATOM   221  O O   . ARG   A 1 31  ? 119.623 130.079 130.535 1.00 56.98  ? 57  ARG   A O   1 
ATOM   222  C CB  . ARG   A 1 31  ? 117.254 128.705 132.407 1.00 59.84  ? 57  ARG   A CB  1 
ATOM   223  C CG  . ARG   A 1 31  ? 117.856 129.711 133.376 1.00 61.49  ? 57  ARG   A CG  1 
ATOM   224  C CD  . ARG   A 1 31  ? 116.941 129.937 134.569 1.00 56.78  ? 57  ARG   A CD  1 
ATOM   225  N NE  . ARG   A 1 31  ? 116.727 131.355 134.828 1.00 58.09  ? 57  ARG   A NE  1 
ATOM   226  C CZ  . ARG   A 1 31  ? 116.161 131.849 135.921 1.00 69.33  ? 57  ARG   A CZ  1 
ATOM   227  N NH1 . ARG   A 1 31  ? 115.759 131.068 136.912 1.00 71.00  ? 57  ARG   A NH1 1 
ATOM   228  N NH2 . ARG   A 1 31  ? 115.993 133.164 136.025 1.00 77.27  ? 57  ARG   A NH2 1 
ATOM   229  N N   . PRO   A 1 32  ? 117.596 130.062 129.577 1.00 47.08  ? 58  PRO   A N   1 
ATOM   230  C CA  . PRO   A 1 32  ? 117.921 131.247 128.772 1.00 49.67  ? 58  PRO   A CA  1 
ATOM   231  C C   . PRO   A 1 32  ? 118.156 132.483 129.625 1.00 52.31  ? 58  PRO   A C   1 
ATOM   232  O O   . PRO   A 1 32  ? 117.590 132.639 130.709 1.00 57.58  ? 58  PRO   A O   1 
ATOM   233  C CB  . PRO   A 1 32  ? 116.687 131.422 127.882 1.00 52.21  ? 58  PRO   A CB  1 
ATOM   234  C CG  . PRO   A 1 32  ? 116.041 130.105 127.860 1.00 58.10  ? 58  PRO   A CG  1 
ATOM   235  C CD  . PRO   A 1 32  ? 116.281 129.512 129.202 1.00 58.02  ? 58  PRO   A CD  1 
ATOM   236  N N   . THR   A 1 33  ? 119.006 133.370 129.113 1.00 47.78  ? 59  THR   A N   1 
ATOM   237  C CA  . THR   A 1 33  ? 119.285 134.645 129.751 1.00 49.20  ? 59  THR   A CA  1 
ATOM   238  C C   . THR   A 1 33  ? 119.666 135.649 128.673 1.00 55.22  ? 59  THR   A C   1 
ATOM   239  O O   . THR   A 1 33  ? 120.211 135.280 127.631 1.00 58.58  ? 59  THR   A O   1 
ATOM   240  C CB  . THR   A 1 33  ? 120.410 134.524 130.788 1.00 57.32  ? 59  THR   A CB  1 
ATOM   241  O OG1 . THR   A 1 33  ? 120.154 133.408 131.648 1.00 58.78  ? 59  THR   A OG1 1 
ATOM   242  C CG2 . THR   A 1 33  ? 120.509 135.790 131.630 1.00 65.04  ? 59  THR   A CG2 1 
ATOM   243  N N   . ASP   A 1 34  ? 119.374 136.920 128.930 1.00 58.76  ? 60  ASP   A N   1 
ATOM   244  C CA  . ASP   A 1 34  ? 119.696 137.955 127.961 1.00 59.81  ? 60  ASP   A CA  1 
ATOM   245  C C   . ASP   A 1 34  ? 121.212 138.163 127.908 1.00 61.37  ? 60  ASP   A C   1 
ATOM   246  O O   . ASP   A 1 34  ? 121.870 138.160 128.952 1.00 69.26  ? 60  ASP   A O   1 
ATOM   247  C CB  . ASP   A 1 34  ? 118.998 139.262 128.324 1.00 64.29  ? 60  ASP   A CB  1 
ATOM   248  C CG  . ASP   A 1 34  ? 117.490 139.164 128.218 1.00 76.16  ? 60  ASP   A CG  1 
ATOM   249  O OD1 . ASP   A 1 34  ? 116.878 138.465 129.052 1.00 78.52  ? 60  ASP   A OD1 1 
ATOM   250  O OD2 . ASP   A 1 34  ? 116.916 139.785 127.299 1.00 80.57  ? 60  ASP   A OD2 1 
ATOM   251  N N   . PRO   A 1 35  ? 121.799 138.345 126.724 1.00 52.69  ? 61  PRO   A N   1 
ATOM   252  C CA  . PRO   A 1 35  ? 123.265 138.414 126.619 1.00 54.66  ? 61  PRO   A CA  1 
ATOM   253  C C   . PRO   A 1 35  ? 123.882 139.796 126.791 1.00 58.02  ? 61  PRO   A C   1 
ATOM   254  O O   . PRO   A 1 35  ? 125.096 139.925 126.608 1.00 64.68  ? 61  PRO   A O   1 
ATOM   255  C CB  . PRO   A 1 35  ? 123.493 137.921 125.188 1.00 56.32  ? 61  PRO   A CB  1 
ATOM   256  C CG  . PRO   A 1 35  ? 122.351 138.510 124.461 1.00 59.59  ? 61  PRO   A CG  1 
ATOM   257  C CD  . PRO   A 1 35  ? 121.181 138.393 125.385 1.00 58.48  ? 61  PRO   A CD  1 
ATOM   258  N N   . ALA   A 1 36  ? 123.106 140.824 127.132 1.00 52.82  ? 62  ALA   A N   1 
ATOM   259  C CA  . ALA   A 1 36  ? 123.595 142.193 126.991 1.00 57.21  ? 62  ALA   A CA  1 
ATOM   260  C C   . ALA   A 1 36  ? 124.664 142.536 128.028 1.00 57.30  ? 62  ALA   A C   1 
ATOM   261  O O   . ALA   A 1 36  ? 125.722 143.088 127.687 1.00 64.74  ? 62  ALA   A O   1 
ATOM   262  C CB  . ALA   A 1 36  ? 122.421 143.162 127.081 1.00 60.85  ? 62  ALA   A CB  1 
ATOM   263  N N   . SER   A 1 37  ? 124.402 142.230 129.301 1.00 48.64  ? 63  SER   A N   1 
ATOM   264  C CA  . SER   A 1 37  ? 125.302 142.671 130.363 1.00 53.18  ? 63  SER   A CA  1 
ATOM   265  C C   . SER   A 1 37  ? 126.667 142.011 130.237 1.00 61.74  ? 63  SER   A C   1 
ATOM   266  O O   . SER   A 1 37  ? 127.699 142.645 130.499 1.00 68.25  ? 63  SER   A O   1 
ATOM   267  C CB  . SER   A 1 37  ? 124.686 142.376 131.727 1.00 56.28  ? 63  SER   A CB  1 
ATOM   268  O OG  . SER   A 1 37  ? 125.237 143.220 132.721 1.00 56.08  ? 63  SER   A OG  1 
ATOM   269  N N   . LEU   A 1 38  ? 126.693 140.741 129.833 1.00 62.90  ? 64  LEU   A N   1 
ATOM   270  C CA  . LEU   A 1 38  ? 127.966 140.067 129.614 1.00 61.09  ? 64  LEU   A CA  1 
ATOM   271  C C   . LEU   A 1 38  ? 128.752 140.739 128.497 1.00 62.48  ? 64  LEU   A C   1 
ATOM   272  O O   . LEU   A 1 38  ? 129.976 140.867 128.585 1.00 66.60  ? 64  LEU   A O   1 
ATOM   273  C CB  . LEU   A 1 38  ? 127.726 138.592 129.298 1.00 58.09  ? 64  LEU   A CB  1 
ATOM   274  C CG  . LEU   A 1 38  ? 128.956 137.690 129.206 1.00 60.45  ? 64  LEU   A CG  1 
ATOM   275  C CD1 . LEU   A 1 38  ? 129.691 137.629 130.531 1.00 61.69  ? 64  LEU   A CD1 1 
ATOM   276  C CD2 . LEU   A 1 38  ? 128.543 136.300 128.761 1.00 68.02  ? 64  LEU   A CD2 1 
ATOM   277  N N   . ALA   A 1 39  ? 128.066 141.176 127.439 1.00 59.10  ? 65  ALA   A N   1 
ATOM   278  C CA  . ALA   A 1 39  ? 128.747 141.882 126.358 1.00 53.93  ? 65  ALA   A CA  1 
ATOM   279  C C   . ALA   A 1 39  ? 129.348 143.195 126.844 1.00 56.33  ? 65  ALA   A C   1 
ATOM   280  O O   . ALA   A 1 39  ? 130.489 143.534 126.494 1.00 66.83  ? 65  ALA   A O   1 
ATOM   281  C CB  . ALA   A 1 39  ? 127.778 142.136 125.208 1.00 53.85  ? 65  ALA   A CB  1 
ATOM   282  N N   . VAL   A 1 40  ? 128.592 143.955 127.638 1.00 51.75  ? 66  VAL   A N   1 
ATOM   283  C CA  . VAL   A 1 40  ? 129.114 145.223 128.145 1.00 56.69  ? 66  VAL   A CA  1 
ATOM   284  C C   . VAL   A 1 40  ? 130.331 144.982 129.031 1.00 61.83  ? 66  VAL   A C   1 
ATOM   285  O O   . VAL   A 1 40  ? 131.344 145.696 128.937 1.00 70.37  ? 66  VAL   A O   1 
ATOM   286  C CB  . VAL   A 1 40  ? 128.012 145.995 128.895 1.00 61.01  ? 66  VAL   A CB  1 
ATOM   287  C CG1 . VAL   A 1 40  ? 128.583 147.250 129.536 1.00 62.74  ? 66  VAL   A CG1 1 
ATOM   288  C CG2 . VAL   A 1 40  ? 126.874 146.347 127.950 1.00 61.81  ? 66  VAL   A CG2 1 
ATOM   289  N N   . PHE   A 1 41  ? 130.257 143.973 129.902 1.00 56.63  ? 67  PHE   A N   1 
ATOM   290  C CA  . PHE   A 1 41  ? 131.396 143.670 130.762 1.00 58.63  ? 67  PHE   A CA  1 
ATOM   291  C C   . PHE   A 1 41  ? 132.594 143.214 129.943 1.00 63.42  ? 67  PHE   A C   1 
ATOM   292  O O   . PHE   A 1 41  ? 133.739 143.553 130.265 1.00 70.75  ? 67  PHE   A O   1 
ATOM   293  C CB  . PHE   A 1 41  ? 131.022 142.608 131.793 1.00 58.62  ? 67  PHE   A CB  1 
ATOM   294  C CG  . PHE   A 1 41  ? 132.183 142.149 132.632 1.00 62.42  ? 67  PHE   A CG  1 
ATOM   295  C CD1 . PHE   A 1 41  ? 132.662 142.934 133.665 1.00 65.45  ? 67  PHE   A CD1 1 
ATOM   296  C CD2 . PHE   A 1 41  ? 132.793 140.935 132.387 1.00 61.74  ? 67  PHE   A CD2 1 
ATOM   297  C CE1 . PHE   A 1 41  ? 133.724 142.515 134.433 1.00 66.84  ? 67  PHE   A CE1 1 
ATOM   298  C CE2 . PHE   A 1 41  ? 133.854 140.513 133.153 1.00 61.94  ? 67  PHE   A CE2 1 
ATOM   299  C CZ  . PHE   A 1 41  ? 134.320 141.304 134.177 1.00 65.91  ? 67  PHE   A CZ  1 
ATOM   300  N N   . ARG   A 1 42  ? 132.351 142.429 128.890 1.00 54.67  ? 68  ARG   A N   1 
ATOM   301  C CA  . ARG   A 1 42  ? 133.426 142.019 127.995 1.00 51.63  ? 68  ARG   A CA  1 
ATOM   302  C C   . ARG   A 1 42  ? 134.127 143.229 127.404 1.00 58.69  ? 68  ARG   A C   1 
ATOM   303  O O   . ARG   A 1 42  ? 135.363 143.300 127.399 1.00 67.11  ? 68  ARG   A O   1 
ATOM   304  C CB  . ARG   A 1 42  ? 132.850 141.129 126.887 1.00 55.85  ? 68  ARG   A CB  1 
ATOM   305  C CG  . ARG   A 1 42  ? 133.789 140.785 125.718 1.00 57.44  ? 68  ARG   A CG  1 
ATOM   306  C CD  . ARG   A 1 42  ? 133.064 140.014 124.620 1.00 59.83  ? 68  ARG   A CD  1 
ATOM   307  N NE  . ARG   A 1 42  ? 131.928 140.747 124.068 1.00 59.30  ? 68  ARG   A NE  1 
ATOM   308  C CZ  . ARG   A 1 42  ? 132.015 141.784 123.243 1.00 53.65  ? 68  ARG   A CZ  1 
ATOM   309  N NH1 . ARG   A 1 42  ? 133.182 142.265 122.848 1.00 54.72  ? 68  ARG   A NH1 1 
ATOM   310  N NH2 . ARG   A 1 42  ? 130.899 142.360 122.809 1.00 57.16  ? 68  ARG   A NH2 1 
ATOM   311  N N   . PHE   A 1 43  ? 133.353 144.190 126.897 1.00 58.65  ? 69  PHE   A N   1 
ATOM   312  C CA  . PHE   A 1 43  ? 133.953 145.371 126.286 1.00 61.48  ? 69  PHE   A CA  1 
ATOM   313  C C   . PHE   A 1 43  ? 134.784 146.149 127.297 1.00 68.42  ? 69  PHE   A C   1 
ATOM   314  O O   . PHE   A 1 43  ? 135.925 146.539 127.012 1.00 76.05  ? 69  PHE   A O   1 
ATOM   315  C CB  . PHE   A 1 43  ? 132.870 146.264 125.686 1.00 60.86  ? 69  PHE   A CB  1 
ATOM   316  C CG  . PHE   A 1 43  ? 133.404 147.520 125.068 1.00 64.96  ? 69  PHE   A CG  1 
ATOM   317  C CD1 . PHE   A 1 43  ? 133.968 147.498 123.807 1.00 74.25  ? 69  PHE   A CD1 1 
ATOM   318  C CD2 . PHE   A 1 43  ? 133.346 148.721 125.749 1.00 68.08  ? 69  PHE   A CD2 1 
ATOM   319  C CE1 . PHE   A 1 43  ? 134.464 148.653 123.236 1.00 78.47  ? 69  PHE   A CE1 1 
ATOM   320  C CE2 . PHE   A 1 43  ? 133.840 149.877 125.182 1.00 73.21  ? 69  PHE   A CE2 1 
ATOM   321  C CZ  . PHE   A 1 43  ? 134.399 149.843 123.925 1.00 76.19  ? 69  PHE   A CZ  1 
ATOM   322  N N   . LEU   A 1 44  ? 134.232 146.378 128.492 1.00 66.81  ? 70  LEU   A N   1 
ATOM   323  C CA  . LEU   A 1 44  ? 134.960 147.163 129.485 1.00 65.31  ? 70  LEU   A CA  1 
ATOM   324  C C   . LEU   A 1 44  ? 136.237 146.456 129.929 1.00 64.72  ? 70  LEU   A C   1 
ATOM   325  O O   . LEU   A 1 44  ? 137.302 147.082 130.024 1.00 70.73  ? 70  LEU   A O   1 
ATOM   326  C CB  . LEU   A 1 44  ? 134.062 147.452 130.687 1.00 69.18  ? 70  LEU   A CB  1 
ATOM   327  C CG  . LEU   A 1 44  ? 132.830 148.320 130.423 1.00 73.42  ? 70  LEU   A CG  1 
ATOM   328  C CD1 . LEU   A 1 44  ? 131.953 148.377 131.660 1.00 75.39  ? 70  LEU   A CD1 1 
ATOM   329  C CD2 . LEU   A 1 44  ? 133.222 149.722 129.989 1.00 71.77  ? 70  LEU   A CD2 1 
ATOM   330  N N   . PHE   A 1 45  ? 136.157 145.147 130.182 1.00 61.00  ? 71  PHE   A N   1 
ATOM   331  C CA  . PHE   A 1 45  ? 137.334 144.399 130.610 1.00 65.25  ? 71  PHE   A CA  1 
ATOM   332  C C   . PHE   A 1 45  ? 138.407 144.396 129.530 1.00 68.62  ? 71  PHE   A C   1 
ATOM   333  O O   . PHE   A 1 45  ? 139.593 144.603 129.821 1.00 74.94  ? 71  PHE   A O   1 
ATOM   334  C CB  . PHE   A 1 45  ? 136.929 142.972 130.978 1.00 67.53  ? 71  PHE   A CB  1 
ATOM   335  C CG  . PHE   A 1 45  ? 138.073 142.107 131.423 1.00 67.59  ? 71  PHE   A CG  1 
ATOM   336  C CD1 . PHE   A 1 45  ? 138.668 142.303 132.655 1.00 66.44  ? 71  PHE   A CD1 1 
ATOM   337  C CD2 . PHE   A 1 45  ? 138.537 141.084 130.619 1.00 64.49  ? 71  PHE   A CD2 1 
ATOM   338  C CE1 . PHE   A 1 45  ? 139.712 141.505 133.066 1.00 66.68  ? 71  PHE   A CE1 1 
ATOM   339  C CE2 . PHE   A 1 45  ? 139.579 140.284 131.027 1.00 63.42  ? 71  PHE   A CE2 1 
ATOM   340  C CZ  . PHE   A 1 45  ? 140.167 140.494 132.252 1.00 65.68  ? 71  PHE   A CZ  1 
ATOM   341  N N   . GLY   A 1 46  ? 138.011 144.170 128.275 1.00 64.57  ? 72  GLY   A N   1 
ATOM   342  C CA  . GLY   A 1 46  ? 138.984 144.170 127.197 1.00 63.78  ? 72  GLY   A CA  1 
ATOM   343  C C   . GLY   A 1 46  ? 139.656 145.516 127.023 1.00 65.83  ? 72  GLY   A C   1 
ATOM   344  O O   . GLY   A 1 46  ? 140.872 145.592 126.840 1.00 69.29  ? 72  GLY   A O   1 
ATOM   345  N N   . PHE   A 1 47  ? 138.876 146.598 127.085 1.00 66.30  ? 73  PHE   A N   1 
ATOM   346  C CA  . PHE   A 1 47  ? 139.460 147.928 126.948 1.00 66.66  ? 73  PHE   A CA  1 
ATOM   347  C C   . PHE   A 1 47  ? 140.434 148.220 128.081 1.00 69.24  ? 73  PHE   A C   1 
ATOM   348  O O   . PHE   A 1 47  ? 141.521 148.773 127.854 1.00 77.02  ? 73  PHE   A O   1 
ATOM   349  C CB  . PHE   A 1 47  ? 138.349 148.976 126.902 1.00 70.63  ? 73  PHE   A CB  1 
ATOM   350  C CG  . PHE   A 1 47  ? 138.832 150.369 126.613 1.00 78.63  ? 73  PHE   A CG  1 
ATOM   351  C CD1 . PHE   A 1 47  ? 139.436 150.674 125.406 1.00 81.82  ? 73  PHE   A CD1 1 
ATOM   352  C CD2 . PHE   A 1 47  ? 138.656 151.379 127.539 1.00 79.76  ? 73  PHE   A CD2 1 
ATOM   353  C CE1 . PHE   A 1 47  ? 139.873 151.956 125.138 1.00 81.06  ? 73  PHE   A CE1 1 
ATOM   354  C CE2 . PHE   A 1 47  ? 139.088 152.661 127.277 1.00 81.41  ? 73  PHE   A CE2 1 
ATOM   355  C CZ  . PHE   A 1 47  ? 139.696 152.950 126.075 1.00 79.85  ? 73  PHE   A CZ  1 
ATOM   356  N N   . LEU   A 1 48  ? 140.069 147.851 129.311 1.00 69.89  ? 74  LEU   A N   1 
ATOM   357  C CA  . LEU   A 1 48  ? 140.960 148.105 130.438 1.00 73.00  ? 74  LEU   A CA  1 
ATOM   358  C C   . LEU   A 1 48  ? 142.254 147.310 130.312 1.00 75.53  ? 74  LEU   A C   1 
ATOM   359  O O   . LEU   A 1 48  ? 143.338 147.839 130.579 1.00 78.19  ? 74  LEU   A O   1 
ATOM   360  C CB  . LEU   A 1 48  ? 140.251 147.782 131.753 1.00 71.32  ? 74  LEU   A CB  1 
ATOM   361  C CG  . LEU   A 1 48  ? 139.119 148.731 132.161 1.00 76.96  ? 74  LEU   A CG  1 
ATOM   362  C CD1 . LEU   A 1 48  ? 138.375 148.195 133.372 1.00 75.97  ? 74  LEU   A CD1 1 
ATOM   363  C CD2 . LEU   A 1 48  ? 139.644 150.128 132.451 1.00 80.65  ? 74  LEU   A CD2 1 
ATOM   364  N N   . MET   A 1 49  ? 142.173 146.044 129.894 1.00 73.91  ? 75  MET   A N   1 
ATOM   365  C CA  . MET   A 1 49  ? 143.399 145.265 129.731 1.00 70.59  ? 75  MET   A CA  1 
ATOM   366  C C   . MET   A 1 49  ? 144.248 145.794 128.577 1.00 72.63  ? 75  MET   A C   1 
ATOM   367  O O   . MET   A 1 49  ? 145.484 145.768 128.649 1.00 78.90  ? 75  MET   A O   1 
ATOM   368  C CB  . MET   A 1 49  ? 143.070 143.787 129.526 1.00 68.10  ? 75  MET   A CB  1 
ATOM   369  C CG  . MET   A 1 49  ? 142.407 143.102 130.723 1.00 70.79  ? 75  MET   A CG  1 
ATOM   370  S SD  . MET   A 1 49  ? 143.287 143.239 132.295 1.00 93.07  ? 75  MET   A SD  1 
ATOM   371  C CE  . MET   A 1 49  ? 144.769 142.292 131.967 1.00 80.17  ? 75  MET   A CE  1 
ATOM   372  N N   . VAL   A 1 50  ? 143.609 146.280 127.509 1.00 73.35  ? 76  VAL   A N   1 
ATOM   373  C CA  . VAL   A 1 50  ? 144.356 146.894 126.413 1.00 68.17  ? 76  VAL   A CA  1 
ATOM   374  C C   . VAL   A 1 50  ? 145.130 148.102 126.918 1.00 69.38  ? 76  VAL   A C   1 
ATOM   375  O O   . VAL   A 1 50  ? 146.308 148.285 126.590 1.00 71.72  ? 76  VAL   A O   1 
ATOM   376  C CB  . VAL   A 1 50  ? 143.403 147.268 125.259 1.00 69.44  ? 76  VAL   A CB  1 
ATOM   377  C CG1 . VAL   A 1 50  ? 144.053 148.254 124.298 1.00 66.52  ? 76  VAL   A CG1 1 
ATOM   378  C CG2 . VAL   A 1 50  ? 142.977 146.026 124.502 1.00 74.67  ? 76  VAL   A CG2 1 
ATOM   379  N N   . LEU   A 1 51  ? 144.485 148.947 127.724 1.00 73.93  ? 77  LEU   A N   1 
ATOM   380  C CA  . LEU   A 1 51  ? 145.203 150.078 128.303 1.00 77.20  ? 77  LEU   A CA  1 
ATOM   381  C C   . LEU   A 1 51  ? 146.273 149.624 129.288 1.00 79.85  ? 77  LEU   A C   1 
ATOM   382  O O   . LEU   A 1 51  ? 147.279 150.319 129.469 1.00 82.94  ? 77  LEU   A O   1 
ATOM   383  C CB  . LEU   A 1 51  ? 144.233 151.035 128.998 1.00 74.85  ? 77  LEU   A CB  1 
ATOM   384  C CG  . LEU   A 1 51  ? 143.349 151.935 128.129 1.00 77.29  ? 77  LEU   A CG  1 
ATOM   385  C CD1 . LEU   A 1 51  ? 142.422 152.756 129.007 1.00 82.45  ? 77  LEU   A CD1 1 
ATOM   386  C CD2 . LEU   A 1 51  ? 144.173 152.852 127.239 1.00 80.24  ? 77  LEU   A CD2 1 
ATOM   387  N N   . ASP   A 1 52  ? 146.079 148.474 129.935 1.00 75.05  ? 78  ASP   A N   1 
ATOM   388  C CA  . ASP   A 1 52  ? 146.977 148.050 131.001 1.00 73.73  ? 78  ASP   A CA  1 
ATOM   389  C C   . ASP   A 1 52  ? 148.219 147.326 130.499 1.00 73.27  ? 78  ASP   A C   1 
ATOM   390  O O   . ASP   A 1 52  ? 149.217 147.276 131.226 1.00 81.91  ? 78  ASP   A O   1 
ATOM   391  C CB  . ASP   A 1 52  ? 146.229 147.135 131.973 1.00 81.17  ? 78  ASP   A CB  1 
ATOM   392  C CG  . ASP   A 1 52  ? 146.986 146.906 133.269 1.00 89.03  ? 78  ASP   A CG  1 
ATOM   393  O OD1 . ASP   A 1 52  ? 147.946 147.655 133.552 1.00 85.47  ? 78  ASP   A OD1 1 
ATOM   394  O OD2 . ASP   A 1 52  ? 146.620 145.970 134.010 1.00 93.53  ? 78  ASP   A OD2 1 
ATOM   395  N N   . ILE   A 1 53  ? 148.188 146.753 129.292 1.00 74.16  ? 79  ILE   A N   1 
ATOM   396  C CA  . ILE   A 1 53  ? 149.353 146.012 128.798 1.00 73.27  ? 79  ILE   A CA  1 
ATOM   397  C C   . ILE   A 1 53  ? 150.591 146.897 128.673 1.00 77.33  ? 79  ILE   A C   1 
ATOM   398  O O   . ILE   A 1 53  ? 151.674 146.466 129.101 1.00 83.04  ? 79  ILE   A O   1 
ATOM   399  C CB  . ILE   A 1 53  ? 149.003 145.278 127.492 1.00 76.82  ? 79  ILE   A CB  1 
ATOM   400  C CG1 . ILE   A 1 53  ? 148.131 144.059 127.797 1.00 80.62  ? 79  ILE   A CG1 1 
ATOM   401  C CG2 . ILE   A 1 53  ? 150.266 144.830 126.753 1.00 75.55  ? 79  ILE   A CG2 1 
ATOM   402  C CD1 . ILE   A 1 53  ? 147.358 143.530 126.602 1.00 75.10  ? 79  ILE   A CD1 1 
ATOM   403  N N   . PRO   A 1 54  ? 150.523 148.110 128.114 1.00 80.92  ? 80  PRO   A N   1 
ATOM   404  C CA  . PRO   A 1 54  ? 151.744 148.917 127.992 1.00 79.11  ? 80  PRO   A CA  1 
ATOM   405  C C   . PRO   A 1 54  ? 152.185 149.621 129.268 1.00 79.72  ? 80  PRO   A C   1 
ATOM   406  O O   . PRO   A 1 54  ? 153.221 150.295 129.239 1.00 82.98  ? 80  PRO   A O   1 
ATOM   407  C CB  . PRO   A 1 54  ? 151.372 149.947 126.910 1.00 79.99  ? 80  PRO   A CB  1 
ATOM   408  C CG  . PRO   A 1 54  ? 150.168 149.404 126.245 1.00 83.57  ? 80  PRO   A CG  1 
ATOM   409  C CD  . PRO   A 1 54  ? 149.433 148.715 127.330 1.00 83.95  ? 80  PRO   A CD  1 
ATOM   410  N N   . GLN   A 1 55  ? 151.456 149.489 130.378 1.00 77.46  ? 81  GLN   A N   1 
ATOM   411  C CA  . GLN   A 1 55  ? 151.750 150.217 131.608 1.00 72.35  ? 81  GLN   A CA  1 
ATOM   412  C C   . GLN   A 1 55  ? 152.258 149.328 132.733 1.00 77.63  ? 81  GLN   A C   1 
ATOM   413  O O   . GLN   A 1 55  ? 153.340 149.581 133.272 1.00 81.84  ? 81  GLN   A O   1 
ATOM   414  C CB  . GLN   A 1 55  ? 150.497 150.964 132.079 1.00 77.44  ? 81  GLN   A CB  1 
ATOM   415  C CG  . GLN   A 1 55  ? 150.064 152.082 131.155 1.00 84.70  ? 81  GLN   A CG  1 
ATOM   416  C CD  . GLN   A 1 55  ? 148.899 152.870 131.710 1.00 95.45  ? 81  GLN   A CD  1 
ATOM   417  O OE1 . GLN   A 1 55  ? 148.422 152.600 132.811 1.00 97.65  ? 81  GLN   A OE1 1 
ATOM   418  N NE2 . GLN   A 1 55  ? 148.432 153.851 130.949 1.00 98.11  ? 81  GLN   A NE2 1 
ATOM   419  N N   . GLU   A 1 56  ? 151.510 148.286 133.099 1.00 80.64  ? 82  GLU   A N   1 
ATOM   420  C CA  . GLU   A 1 56  ? 151.845 147.446 134.244 1.00 79.57  ? 82  GLU   A CA  1 
ATOM   421  C C   . GLU   A 1 56  ? 152.470 146.117 133.852 1.00 77.72  ? 82  GLU   A C   1 
ATOM   422  O O   . GLU   A 1 56  ? 153.343 145.624 134.573 1.00 82.89  ? 82  GLU   A O   1 
ATOM   423  C CB  . GLU   A 1 56  ? 150.594 147.176 135.086 1.00 82.52  ? 82  GLU   A CB  1 
ATOM   424  C CG  . GLU   A 1 56  ? 150.879 146.527 136.433 1.00 87.21  ? 82  GLU   A CG  1 
ATOM   425  C CD  . GLU   A 1 56  ? 149.638 146.402 137.296 1.00 92.01  ? 82  GLU   A CD  1 
ATOM   426  O OE1 . GLU   A 1 56  ? 148.558 146.850 136.857 1.00 96.19  ? 82  GLU   A OE1 1 
ATOM   427  O OE2 . GLU   A 1 56  ? 149.743 145.854 138.413 1.00 87.92  ? 82  GLU   A OE2 1 
ATOM   428  N N   . ARG   A 1 57  ? 152.047 145.522 132.736 1.00 71.68  ? 83  ARG   A N   1 
ATOM   429  C CA  . ARG   A 1 57  ? 152.654 144.270 132.299 1.00 78.27  ? 83  ARG   A CA  1 
ATOM   430  C C   . ARG   A 1 57  ? 154.118 144.464 131.925 1.00 83.29  ? 83  ARG   A C   1 
ATOM   431  O O   . ARG   A 1 57  ? 154.899 143.507 131.970 1.00 87.17  ? 83  ARG   A O   1 
ATOM   432  C CB  . ARG   A 1 57  ? 151.875 143.688 131.119 1.00 86.48  ? 83  ARG   A CB  1 
ATOM   433  C CG  . ARG   A 1 57  ? 150.419 143.323 131.415 1.00 87.92  ? 83  ARG   A CG  1 
ATOM   434  C CD  . ARG   A 1 57  ? 150.274 141.954 132.073 1.00 85.84  ? 83  ARG   A CD  1 
ATOM   435  N NE  . ARG   A 1 57  ? 150.660 141.956 133.480 1.00 87.42  ? 83  ARG   A NE  1 
ATOM   436  C CZ  . ARG   A 1 57  ? 149.880 142.332 134.487 1.00 92.09  ? 83  ARG   A CZ  1 
ATOM   437  N NH1 . ARG   A 1 57  ? 148.646 142.774 134.289 1.00 90.05  ? 83  ARG   A NH1 1 
ATOM   438  N NH2 . ARG   A 1 57  ? 150.351 142.267 135.729 1.00 86.05  ? 83  ARG   A NH2 1 
ATOM   439  N N   . GLY   A 1 58  ? 154.501 145.677 131.546 1.00 84.42  ? 84  GLY   A N   1 
ATOM   440  C CA  . GLY   A 1 58  ? 155.888 146.033 131.362 1.00 84.53  ? 84  GLY   A CA  1 
ATOM   441  C C   . GLY   A 1 58  ? 156.379 146.065 129.935 1.00 81.46  ? 84  GLY   A C   1 
ATOM   442  O O   . GLY   A 1 58  ? 157.548 145.742 129.697 1.00 89.33  ? 84  GLY   A O   1 
ATOM   443  N N   . LEU   A 1 59  ? 155.532 146.439 128.976 1.00 72.53  ? 85  LEU   A N   1 
ATOM   444  C CA  . LEU   A 1 59  ? 155.982 146.497 127.592 1.00 72.65  ? 85  LEU   A CA  1 
ATOM   445  C C   . LEU   A 1 59  ? 157.005 147.606 127.381 1.00 81.02  ? 85  LEU   A C   1 
ATOM   446  O O   . LEU   A 1 59  ? 157.893 147.475 126.531 1.00 85.23  ? 85  LEU   A O   1 
ATOM   447  C CB  . LEU   A 1 59  ? 154.785 146.691 126.662 1.00 77.43  ? 85  LEU   A CB  1 
ATOM   448  C CG  . LEU   A 1 59  ? 154.996 146.468 125.162 1.00 79.95  ? 85  LEU   A CG  1 
ATOM   449  C CD1 . LEU   A 1 59  ? 155.452 145.053 124.876 1.00 72.49  ? 85  LEU   A CD1 1 
ATOM   450  C CD2 . LEU   A 1 59  ? 153.717 146.768 124.397 1.00 82.08  ? 85  LEU   A CD2 1 
ATOM   451  N N   . SER   A 1 60  ? 156.901 148.700 128.138 1.00 86.21  ? 86  SER   A N   1 
ATOM   452  C CA  . SER   A 1 60  ? 157.834 149.809 127.973 1.00 89.35  ? 86  SER   A CA  1 
ATOM   453  C C   . SER   A 1 60  ? 159.198 149.493 128.574 1.00 84.11  ? 86  SER   A C   1 
ATOM   454  O O   . SER   A 1 60  ? 160.228 149.912 128.034 1.00 89.53  ? 86  SER   A O   1 
ATOM   455  C CB  . SER   A 1 60  ? 157.259 151.075 128.607 1.00 90.83  ? 86  SER   A CB  1 
ATOM   456  O OG  . SER   A 1 60  ? 157.059 150.905 129.998 1.00 91.24  ? 86  SER   A OG  1 
ATOM   457  N N   . SER   A 1 61  ? 159.224 148.756 129.683 1.00 79.79  ? 87  SER   A N   1 
ATOM   458  C CA  . SER   A 1 61  ? 160.449 148.443 130.403 1.00 84.55  ? 87  SER   A CA  1 
ATOM   459  C C   . SER   A 1 61  ? 161.020 147.077 130.038 1.00 82.84  ? 87  SER   A C   1 
ATOM   460  O O   . SER   A 1 61  ? 161.996 146.642 130.658 1.00 87.89  ? 87  SER   A O   1 
ATOM   461  C CB  . SER   A 1 61  ? 160.196 148.512 131.910 1.00 90.19  ? 87  SER   A CB  1 
ATOM   462  O OG  . SER   A 1 61  ? 161.386 148.283 132.644 1.00 96.12  ? 87  SER   A OG  1 
ATOM   463  N N   . LEU   A 1 62  ? 160.440 146.391 129.053 1.00 76.89  ? 88  LEU   A N   1 
ATOM   464  C CA  . LEU   A 1 62  ? 160.884 145.044 128.720 1.00 73.15  ? 88  LEU   A CA  1 
ATOM   465  C C   . LEU   A 1 62  ? 162.297 145.014 128.155 1.00 72.45  ? 88  LEU   A C   1 
ATOM   466  O O   . LEU   A 1 62  ? 162.958 143.974 128.239 1.00 79.38  ? 88  LEU   A O   1 
ATOM   467  C CB  . LEU   A 1 62  ? 159.919 144.417 127.715 1.00 76.01  ? 88  LEU   A CB  1 
ATOM   468  C CG  . LEU   A 1 62  ? 160.021 142.911 127.480 1.00 75.78  ? 88  LEU   A CG  1 
ATOM   469  C CD1 . LEU   A 1 62  ? 159.457 142.131 128.655 1.00 76.91  ? 88  LEU   A CD1 1 
ATOM   470  C CD2 . LEU   A 1 62  ? 159.295 142.551 126.199 1.00 75.76  ? 88  LEU   A CD2 1 
ATOM   471  N N   . ASP   A 1 63  ? 162.779 146.120 127.590 1.00 73.56  ? 89  ASP   A N   1 
ATOM   472  C CA  . ASP   A 1 63  ? 164.110 146.131 126.997 1.00 81.43  ? 89  ASP   A CA  1 
ATOM   473  C C   . ASP   A 1 63  ? 165.219 146.183 128.038 1.00 85.54  ? 89  ASP   A C   1 
ATOM   474  O O   . ASP   A 1 63  ? 166.342 145.762 127.741 1.00 86.93  ? 89  ASP   A O   1 
ATOM   475  C CB  . ASP   A 1 63  ? 164.257 147.317 126.039 1.00 90.10  ? 89  ASP   A CB  1 
ATOM   476  C CG  . ASP   A 1 63  ? 164.054 148.656 126.723 1.00 94.07  ? 89  ASP   A CG  1 
ATOM   477  O OD1 . ASP   A 1 63  ? 163.623 148.672 127.895 1.00 93.03  ? 89  ASP   A OD1 1 
ATOM   478  O OD2 . ASP   A 1 63  ? 164.323 149.695 126.085 1.00 94.73  ? 89  ASP   A OD2 1 
ATOM   479  N N   . ARG   A 1 64  ? 164.929 146.679 129.242 1.00 87.52  ? 90  ARG   A N   1 
ATOM   480  C CA  . ARG   A 1 64  ? 165.891 146.732 130.337 1.00 82.05  ? 90  ARG   A CA  1 
ATOM   481  C C   . ARG   A 1 64  ? 165.578 145.722 131.433 1.00 73.04  ? 90  ARG   A C   1 
ATOM   482  O O   . ARG   A 1 64  ? 166.147 145.817 132.525 1.00 80.99  ? 90  ARG   A O   1 
ATOM   483  C CB  . ARG   A 1 64  ? 165.946 148.145 130.925 1.00 84.06  ? 90  ARG   A CB  1 
ATOM   484  C CG  . ARG   A 1 64  ? 164.622 148.664 131.474 1.00 87.15  ? 90  ARG   A CG  1 
ATOM   485  C CD  . ARG   A 1 64  ? 164.767 150.069 132.041 1.00 92.59  ? 90  ARG   A CD  1 
ATOM   486  N NE  . ARG   A 1 64  ? 165.160 151.040 131.025 1.00 99.35  ? 90  ARG   A NE  1 
ATOM   487  C CZ  . ARG   A 1 64  ? 165.333 152.338 131.242 1.00 103.46 ? 90  ARG   A CZ  1 
ATOM   488  N NH1 . ARG   A 1 64  ? 165.160 152.874 132.441 1.00 100.44 ? 90  ARG   A NH1 1 
ATOM   489  N NH2 . ARG   A 1 64  ? 165.688 153.122 130.228 1.00 105.42 ? 90  ARG   A NH2 1 
ATOM   490  N N   . LYS   A 1 65  ? 164.692 144.761 131.169 1.00 69.82  ? 91  LYS   A N   1 
ATOM   491  C CA  . LYS   A 1 65  ? 164.322 143.725 132.122 1.00 70.06  ? 91  LYS   A CA  1 
ATOM   492  C C   . LYS   A 1 65  ? 164.721 142.329 131.676 1.00 71.22  ? 91  LYS   A C   1 
ATOM   493  O O   . LYS   A 1 65  ? 165.048 141.498 132.525 1.00 77.84  ? 91  LYS   A O   1 
ATOM   494  C CB  . LYS   A 1 65  ? 162.809 143.757 132.367 1.00 74.53  ? 91  LYS   A CB  1 
ATOM   495  C CG  . LYS   A 1 65  ? 162.342 142.903 133.529 1.00 78.43  ? 91  LYS   A CG  1 
ATOM   496  C CD  . LYS   A 1 65  ? 160.872 143.146 133.827 1.00 86.68  ? 91  LYS   A CD  1 
ATOM   497  C CE  . LYS   A 1 65  ? 160.368 142.242 134.942 1.00 95.03  ? 91  LYS   A CE  1 
ATOM   498  N NZ  . LYS   A 1 65  ? 161.082 142.464 136.231 1.00 94.10  ? 91  LYS   A NZ  1 
ATOM   499  N N   . TYR   A 1 66  ? 164.700 142.056 130.370 1.00 66.34  ? 92  TYR   A N   1 
ATOM   500  C CA  . TYR   A 1 66  ? 165.126 140.783 129.798 1.00 67.32  ? 92  TYR   A CA  1 
ATOM   501  C C   . TYR   A 1 66  ? 166.260 140.984 128.798 1.00 73.48  ? 92  TYR   A C   1 
ATOM   502  O O   . TYR   A 1 66  ? 166.349 140.271 127.796 1.00 78.43  ? 92  TYR   A O   1 
ATOM   503  C CB  . TYR   A 1 66  ? 163.950 140.065 129.137 1.00 67.49  ? 92  TYR   A CB  1 
ATOM   504  C CG  . TYR   A 1 66  ? 162.902 139.575 130.106 1.00 71.37  ? 92  TYR   A CG  1 
ATOM   505  C CD1 . TYR   A 1 66  ? 163.028 138.342 130.725 1.00 77.17  ? 92  TYR   A CD1 1 
ATOM   506  C CD2 . TYR   A 1 66  ? 161.785 140.340 130.395 1.00 71.63  ? 92  TYR   A CD2 1 
ATOM   507  C CE1 . TYR   A 1 66  ? 162.073 137.888 131.609 1.00 74.02  ? 92  TYR   A CE1 1 
ATOM   508  C CE2 . TYR   A 1 66  ? 160.826 139.894 131.277 1.00 73.42  ? 92  TYR   A CE2 1 
ATOM   509  C CZ  . TYR   A 1 66  ? 160.975 138.668 131.881 1.00 72.35  ? 92  TYR   A CZ  1 
ATOM   510  O OH  . TYR   A 1 66  ? 160.020 138.220 132.762 1.00 74.48  ? 92  TYR   A OH  1 
ATOM   511  N N   . LEU   A 1 67  ? 167.126 141.961 129.056 1.00 78.06  ? 93  LEU   A N   1 
ATOM   512  C CA  . LEU   A 1 67  ? 168.217 142.264 128.139 1.00 79.01  ? 93  LEU   A CA  1 
ATOM   513  C C   . LEU   A 1 67  ? 169.146 141.066 127.991 1.00 75.28  ? 93  LEU   A C   1 
ATOM   514  O O   . LEU   A 1 67  ? 169.513 140.415 128.972 1.00 79.15  ? 93  LEU   A O   1 
ATOM   515  C CB  . LEU   A 1 67  ? 168.996 143.482 128.640 1.00 80.99  ? 93  LEU   A CB  1 
ATOM   516  C CG  . LEU   A 1 67  ? 170.149 144.004 127.776 1.00 86.17  ? 93  LEU   A CG  1 
ATOM   517  C CD1 . LEU   A 1 67  ? 169.675 144.379 126.379 1.00 84.10  ? 93  LEU   A CD1 1 
ATOM   518  C CD2 . LEU   A 1 67  ? 170.806 145.197 128.451 1.00 84.64  ? 93  LEU   A CD2 1 
ATOM   519  N N   . ASP   A 1 68  ? 169.521 140.774 126.749 1.00 77.03  ? 94  ASP   A N   1 
ATOM   520  C CA  . ASP   A 1 68  ? 170.369 139.624 126.473 1.00 85.29  ? 94  ASP   A CA  1 
ATOM   521  C C   . ASP   A 1 68  ? 171.795 139.884 126.938 1.00 89.04  ? 94  ASP   A C   1 
ATOM   522  O O   . ASP   A 1 68  ? 172.320 140.992 126.800 1.00 84.74  ? 94  ASP   A O   1 
ATOM   523  C CB  . ASP   A 1 68  ? 170.356 139.301 124.980 1.00 92.06  ? 94  ASP   A CB  1 
ATOM   524  C CG  . ASP   A 1 68  ? 168.967 138.975 124.467 1.00 98.03  ? 94  ASP   A CG  1 
ATOM   525  O OD1 . ASP   A 1 68  ? 168.155 138.435 125.247 1.00 97.37  ? 94  ASP   A OD1 1 
ATOM   526  O OD2 . ASP   A 1 68  ? 168.688 139.259 123.283 1.00 93.89  ? 94  ASP   A OD2 1 
ATOM   527  N N   . GLY   A 1 69  ? 172.423 138.847 127.492 1.00 99.52  ? 95  GLY   A N   1 
ATOM   528  C CA  . GLY   A 1 69  ? 173.778 138.935 127.989 1.00 100.88 ? 95  GLY   A CA  1 
ATOM   529  C C   . GLY   A 1 69  ? 173.903 139.362 129.435 1.00 96.66  ? 95  GLY   A C   1 
ATOM   530  O O   . GLY   A 1 69  ? 174.982 139.199 130.019 1.00 91.42  ? 95  GLY   A O   1 
ATOM   531  N N   . LEU   A 1 70  ? 172.840 139.893 130.033 1.00 91.30  ? 96  LEU   A N   1 
ATOM   532  C CA  . LEU   A 1 70  ? 172.874 140.352 131.413 1.00 83.03  ? 96  LEU   A CA  1 
ATOM   533  C C   . LEU   A 1 70  ? 172.577 139.183 132.341 1.00 84.59  ? 96  LEU   A C   1 
ATOM   534  O O   . LEU   A 1 70  ? 171.648 138.408 132.093 1.00 81.63  ? 96  LEU   A O   1 
ATOM   535  C CB  . LEU   A 1 70  ? 171.858 141.473 131.630 1.00 82.97  ? 96  LEU   A CB  1 
ATOM   536  C CG  . LEU   A 1 70  ? 171.913 142.200 132.975 1.00 84.00  ? 96  LEU   A CG  1 
ATOM   537  C CD1 . LEU   A 1 70  ? 173.196 143.008 133.109 1.00 83.33  ? 96  LEU   A CD1 1 
ATOM   538  C CD2 . LEU   A 1 70  ? 170.694 143.093 133.140 1.00 83.12  ? 96  LEU   A CD2 1 
ATOM   539  N N   . ASP   A 1 71  ? 173.365 139.065 133.407 1.00 90.04  ? 97  ASP   A N   1 
ATOM   540  C CA  . ASP   A 1 71  ? 173.224 137.979 134.379 1.00 86.97  ? 97  ASP   A CA  1 
ATOM   541  C C   . ASP   A 1 71  ? 172.442 138.514 135.574 1.00 78.97  ? 97  ASP   A C   1 
ATOM   542  O O   . ASP   A 1 71  ? 172.965 139.281 136.385 1.00 74.09  ? 97  ASP   A O   1 
ATOM   543  C CB  . ASP   A 1 71  ? 174.583 137.413 134.789 1.00 79.80  ? 97  ASP   A CB  1 
ATOM   544  C CG  . ASP   A 1 71  ? 175.571 138.480 135.219 1.00 81.61  ? 97  ASP   A CG  1 
ATOM   545  O OD1 . ASP   A 1 71  ? 175.259 139.680 135.072 1.00 85.93  ? 97  ASP   A OD1 1 
ATOM   546  O OD2 . ASP   A 1 71  ? 176.665 138.116 135.698 1.00 80.31  ? 97  ASP   A OD2 1 
ATOM   547  N N   . VAL   A 1 72  ? 171.173 138.113 135.666 1.00 73.99  ? 98  VAL   A N   1 
ATOM   548  C CA  . VAL   A 1 72  ? 170.289 138.488 136.759 1.00 72.76  ? 98  VAL   A CA  1 
ATOM   549  C C   . VAL   A 1 72  ? 169.592 137.224 137.243 1.00 76.78  ? 98  VAL   A C   1 
ATOM   550  O O   . VAL   A 1 72  ? 169.461 136.241 136.513 1.00 77.00  ? 98  VAL   A O   1 
ATOM   551  C CB  . VAL   A 1 72  ? 169.255 139.559 136.339 1.00 77.22  ? 98  VAL   A CB  1 
ATOM   552  C CG1 . VAL   A 1 72  ? 168.556 140.158 137.557 1.00 80.08  ? 98  VAL   A CG1 1 
ATOM   553  C CG2 . VAL   A 1 72  ? 169.922 140.647 135.505 1.00 78.56  ? 98  VAL   A CG2 1 
ATOM   554  N N   . CYS   A 1 73  ? 169.147 137.261 138.497 1.00 80.68  ? 99  CYS   A N   1 
ATOM   555  C CA  . CYS   A 1 73  ? 168.528 136.113 139.150 1.00 71.22  ? 99  CYS   A CA  1 
ATOM   556  C C   . CYS   A 1 73  ? 167.015 136.219 138.997 1.00 63.89  ? 99  CYS   A C   1 
ATOM   557  O O   . CYS   A 1 73  ? 166.386 137.113 139.571 1.00 68.84  ? 99  CYS   A O   1 
ATOM   558  C CB  . CYS   A 1 73  ? 168.927 136.051 140.622 1.00 65.52  ? 99  CYS   A CB  1 
ATOM   559  S SG  . CYS   A 1 73  ? 170.709 136.109 140.915 1.00 89.93  ? 99  CYS   A SG  1 
ATOM   560  N N   . ARG   A 1 74  ? 166.436 135.302 138.231 1.00 57.18  ? 100 ARG   A N   1 
ATOM   561  C CA  . ARG   A 1 74  ? 164.994 135.212 138.079 1.00 66.13  ? 100 ARG   A CA  1 
ATOM   562  C C   . ARG   A 1 74  ? 164.408 134.402 139.230 1.00 70.00  ? 100 ARG   A C   1 
ATOM   563  O O   . ARG   A 1 74  ? 165.115 133.678 139.934 1.00 69.25  ? 100 ARG   A O   1 
ATOM   564  C CB  . ARG   A 1 74  ? 164.622 134.555 136.745 1.00 75.99  ? 100 ARG   A CB  1 
ATOM   565  C CG  . ARG   A 1 74  ? 165.374 135.069 135.520 1.00 76.24  ? 100 ARG   A CG  1 
ATOM   566  C CD  . ARG   A 1 74  ? 165.091 136.531 135.233 1.00 74.27  ? 100 ARG   A CD  1 
ATOM   567  N NE  . ARG   A 1 74  ? 165.827 136.994 134.062 1.00 70.46  ? 100 ARG   A NE  1 
ATOM   568  C CZ  . ARG   A 1 74  ? 165.887 138.253 133.649 1.00 72.39  ? 100 ARG   A CZ  1 
ATOM   569  N NH1 . ARG   A 1 74  ? 165.245 139.225 134.278 1.00 78.94  ? 100 ARG   A NH1 1 
ATOM   570  N NH2 . ARG   A 1 74  ? 166.619 138.548 132.579 1.00 70.08  ? 100 ARG   A NH2 1 
ATOM   571  N N   . PHE   A 1 75  ? 163.096 134.536 139.417 1.00 69.60  ? 101 PHE   A N   1 
ATOM   572  C CA  . PHE   A 1 75  ? 162.354 133.793 140.437 1.00 65.13  ? 101 PHE   A CA  1 
ATOM   573  C C   . PHE   A 1 75  ? 161.113 133.168 139.810 1.00 66.66  ? 101 PHE   A C   1 
ATOM   574  O O   . PHE   A 1 75  ? 159.982 133.568 140.108 1.00 72.24  ? 101 PHE   A O   1 
ATOM   575  C CB  . PHE   A 1 75  ? 161.974 134.702 141.605 1.00 66.09  ? 101 PHE   A CB  1 
ATOM   576  C CG  . PHE   A 1 75  ? 163.154 135.277 142.336 1.00 62.48  ? 101 PHE   A CG  1 
ATOM   577  C CD1 . PHE   A 1 75  ? 163.916 134.488 143.175 1.00 61.49  ? 101 PHE   A CD1 1 
ATOM   578  C CD2 . PHE   A 1 75  ? 163.494 136.607 142.193 1.00 61.16  ? 101 PHE   A CD2 1 
ATOM   579  C CE1 . PHE   A 1 75  ? 164.997 135.016 143.849 1.00 59.94  ? 101 PHE   A CE1 1 
ATOM   580  C CE2 . PHE   A 1 75  ? 164.574 137.137 142.866 1.00 60.72  ? 101 PHE   A CE2 1 
ATOM   581  C CZ  . PHE   A 1 75  ? 165.324 136.341 143.693 1.00 61.08  ? 101 PHE   A CZ  1 
ATOM   582  N N   . PRO   A 1 76  ? 161.288 132.182 138.935 1.00 62.15  ? 102 PRO   A N   1 
ATOM   583  C CA  . PRO   A 1 76  ? 160.133 131.488 138.363 1.00 62.53  ? 102 PRO   A CA  1 
ATOM   584  C C   . PRO   A 1 76  ? 159.561 130.459 139.325 1.00 66.47  ? 102 PRO   A C   1 
ATOM   585  O O   . PRO   A 1 76  ? 160.243 129.949 140.216 1.00 70.35  ? 102 PRO   A O   1 
ATOM   586  C CB  . PRO   A 1 76  ? 160.715 130.814 137.118 1.00 66.15  ? 102 PRO   A CB  1 
ATOM   587  C CG  . PRO   A 1 76  ? 162.123 130.544 137.487 1.00 66.81  ? 102 PRO   A CG  1 
ATOM   588  C CD  . PRO   A 1 76  ? 162.553 131.689 138.363 1.00 67.01  ? 102 PRO   A CD  1 
ATOM   589  N N   . LEU   A 1 77  ? 158.273 130.165 139.135 1.00 64.96  ? 103 LEU   A N   1 
ATOM   590  C CA  . LEU   A 1 77  ? 157.633 129.135 139.946 1.00 67.30  ? 103 LEU   A CA  1 
ATOM   591  C C   . LEU   A 1 77  ? 158.271 127.776 139.692 1.00 71.00  ? 103 LEU   A C   1 
ATOM   592  O O   . LEU   A 1 77  ? 158.505 127.006 140.631 1.00 78.09  ? 103 LEU   A O   1 
ATOM   593  C CB  . LEU   A 1 77  ? 156.131 129.100 139.658 1.00 67.87  ? 103 LEU   A CB  1 
ATOM   594  C CG  . LEU   A 1 77  ? 155.213 128.387 140.664 1.00 73.04  ? 103 LEU   A CG  1 
ATOM   595  C CD1 . LEU   A 1 77  ? 153.768 128.808 140.455 1.00 71.46  ? 103 LEU   A CD1 1 
ATOM   596  C CD2 . LEU   A 1 77  ? 155.312 126.868 140.585 1.00 72.83  ? 103 LEU   A CD2 1 
ATOM   597  N N   . LEU   A 1 78  ? 158.568 127.472 138.432 1.00 72.07  ? 104 LEU   A N   1 
ATOM   598  C CA  . LEU   A 1 78  ? 159.256 126.252 138.039 1.00 75.82  ? 104 LEU   A CA  1 
ATOM   599  C C   . LEU   A 1 78  ? 160.652 126.600 137.546 1.00 79.49  ? 104 LEU   A C   1 
ATOM   600  O O   . LEU   A 1 78  ? 160.827 127.537 136.762 1.00 87.19  ? 104 LEU   A O   1 
ATOM   601  C CB  . LEU   A 1 78  ? 158.495 125.514 136.933 1.00 80.37  ? 104 LEU   A CB  1 
ATOM   602  C CG  . LEU   A 1 78  ? 157.088 124.995 137.238 1.00 82.97  ? 104 LEU   A CG  1 
ATOM   603  C CD1 . LEU   A 1 78  ? 156.033 126.035 136.904 1.00 77.92  ? 104 LEU   A CD1 1 
ATOM   604  C CD2 . LEU   A 1 78  ? 156.825 123.707 136.476 1.00 80.95  ? 104 LEU   A CD2 1 
ATOM   605  N N   . ASP   A 1 79  ? 161.645 125.838 138.004 1.00 80.52  ? 105 ASP   A N   1 
ATOM   606  C CA  . ASP   A 1 79  ? 163.006 126.043 137.525 1.00 88.93  ? 105 ASP   A CA  1 
ATOM   607  C C   . ASP   A 1 79  ? 163.170 125.639 136.066 1.00 83.44  ? 105 ASP   A C   1 
ATOM   608  O O   . ASP   A 1 79  ? 164.154 126.034 135.434 1.00 81.35  ? 105 ASP   A O   1 
ATOM   609  C CB  . ASP   A 1 79  ? 163.993 125.266 138.395 1.00 94.02  ? 105 ASP   A CB  1 
ATOM   610  C CG  . ASP   A 1 79  ? 164.012 125.753 139.830 1.00 95.71  ? 105 ASP   A CG  1 
ATOM   611  O OD1 . ASP   A 1 79  ? 163.712 126.943 140.058 1.00 85.79  ? 105 ASP   A OD1 1 
ATOM   612  O OD2 . ASP   A 1 79  ? 164.329 124.946 140.729 1.00 95.12  ? 105 ASP   A OD2 1 
ATOM   613  N N   . ALA   A 1 80  ? 162.234 124.860 135.519 1.00 81.94  ? 106 ALA   A N   1 
ATOM   614  C CA  . ALA   A 1 80  ? 162.305 124.501 134.109 1.00 85.77  ? 106 ALA   A CA  1 
ATOM   615  C C   . ALA   A 1 80  ? 162.101 125.712 133.208 1.00 84.70  ? 106 ALA   A C   1 
ATOM   616  O O   . ALA   A 1 80  ? 162.710 125.789 132.135 1.00 89.95  ? 106 ALA   A O   1 
ATOM   617  C CB  . ALA   A 1 80  ? 161.270 123.423 133.792 1.00 86.57  ? 106 ALA   A CB  1 
ATOM   618  N N   . LEU   A 1 81  ? 161.250 126.654 133.612 1.00 76.28  ? 107 LEU   A N   1 
ATOM   619  C CA  . LEU   A 1 81  ? 161.011 127.838 132.799 1.00 74.94  ? 107 LEU   A CA  1 
ATOM   620  C C   . LEU   A 1 81  ? 162.283 128.665 132.662 1.00 79.32  ? 107 LEU   A C   1 
ATOM   621  O O   . LEU   A 1 81  ? 163.075 128.778 133.601 1.00 81.94  ? 107 LEU   A O   1 
ATOM   622  C CB  . LEU   A 1 81  ? 159.905 128.700 133.410 1.00 72.49  ? 107 LEU   A CB  1 
ATOM   623  C CG  . LEU   A 1 81  ? 158.479 128.151 133.475 1.00 74.92  ? 107 LEU   A CG  1 
ATOM   624  C CD1 . LEU   A 1 81  ? 157.558 129.211 134.046 1.00 69.91  ? 107 LEU   A CD1 1 
ATOM   625  C CD2 . LEU   A 1 81  ? 157.983 127.698 132.112 1.00 78.90  ? 107 LEU   A CD2 1 
ATOM   626  N N   . ARG   A 1 82  ? 162.474 129.241 131.474 1.00 77.63  ? 108 ARG   A N   1 
ATOM   627  C CA  . ARG   A 1 82  ? 163.566 130.158 131.205 1.00 81.32  ? 108 ARG   A CA  1 
ATOM   628  C C   . ARG   A 1 82  ? 163.012 131.224 130.260 1.00 76.31  ? 108 ARG   A C   1 
ATOM   629  O O   . ARG   A 1 82  ? 162.267 130.880 129.325 1.00 75.01  ? 108 ARG   A O   1 
ATOM   630  C CB  . ARG   A 1 82  ? 164.770 129.453 130.577 1.00 92.01  ? 108 ARG   A CB  1 
ATOM   631  C CG  . ARG   A 1 82  ? 165.349 128.336 131.432 1.00 95.36  ? 108 ARG   A CG  1 
ATOM   632  C CD  . ARG   A 1 82  ? 166.659 127.815 130.860 1.00 98.10  ? 108 ARG   A CD  1 
ATOM   633  N NE  . ARG   A 1 82  ? 166.489 127.218 129.539 1.00 102.70 ? 108 ARG   A NE  1 
ATOM   634  C CZ  . ARG   A 1 82  ? 166.098 125.971 129.307 1.00 106.78 ? 108 ARG   A CZ  1 
ATOM   635  N NH1 . ARG   A 1 82  ? 165.797 125.137 130.292 1.00 102.51 ? 108 ARG   A NH1 1 
ATOM   636  N NH2 . ARG   A 1 82  ? 166.002 125.547 128.050 1.00 107.95 ? 108 ARG   A NH2 1 
ATOM   637  N N   . PRO   A 1 83  ? 163.323 132.512 130.459 1.00 75.31  ? 109 PRO   A N   1 
ATOM   638  C CA  . PRO   A 1 83  ? 162.863 133.514 129.490 1.00 70.51  ? 109 PRO   A CA  1 
ATOM   639  C C   . PRO   A 1 83  ? 163.470 133.289 128.114 1.00 77.54  ? 109 PRO   A C   1 
ATOM   640  O O   . PRO   A 1 83  ? 164.598 132.812 127.976 1.00 83.20  ? 109 PRO   A O   1 
ATOM   641  C CB  . PRO   A 1 83  ? 163.338 134.842 130.090 1.00 68.06  ? 109 PRO   A CB  1 
ATOM   642  C CG  . PRO   A 1 83  ? 163.546 134.580 131.510 1.00 74.22  ? 109 PRO   A CG  1 
ATOM   643  C CD  . PRO   A 1 83  ? 163.968 133.154 131.619 1.00 77.48  ? 109 PRO   A CD  1 
ATOM   644  N N   . LEU   A 1 84  ? 162.702 133.642 127.094 1.00 76.99  ? 110 LEU   A N   1 
ATOM   645  C CA  . LEU   A 1 84  ? 163.174 133.662 125.718 1.00 72.12  ? 110 LEU   A CA  1 
ATOM   646  C C   . LEU   A 1 84  ? 163.868 134.986 125.441 1.00 70.40  ? 110 LEU   A C   1 
ATOM   647  O O   . LEU   A 1 84  ? 163.814 135.909 126.257 1.00 75.32  ? 110 LEU   A O   1 
ATOM   648  C CB  . LEU   A 1 84  ? 161.998 133.446 124.769 1.00 68.43  ? 110 LEU   A CB  1 
ATOM   649  C CG  . LEU   A 1 84  ? 161.131 132.206 125.001 1.00 67.73  ? 110 LEU   A CG  1 
ATOM   650  C CD1 . LEU   A 1 84  ? 160.028 132.143 123.964 1.00 66.64  ? 110 LEU   A CD1 1 
ATOM   651  C CD2 . LEU   A 1 84  ? 161.962 130.932 124.969 1.00 70.53  ? 110 LEU   A CD2 1 
ATOM   652  N N   . PRO   A 1 85  ? 164.560 135.115 124.306 1.00 62.22  ? 111 PRO   A N   1 
ATOM   653  C CA  . PRO   A 1 85  ? 165.180 136.404 123.968 1.00 62.01  ? 111 PRO   A CA  1 
ATOM   654  C C   . PRO   A 1 85  ? 164.155 137.526 123.877 1.00 69.90  ? 111 PRO   A C   1 
ATOM   655  O O   . PRO   A 1 85  ? 162.941 137.314 123.858 1.00 78.52  ? 111 PRO   A O   1 
ATOM   656  C CB  . PRO   A 1 85  ? 165.842 136.134 122.617 1.00 66.95  ? 111 PRO   A CB  1 
ATOM   657  C CG  . PRO   A 1 85  ? 166.146 134.689 122.647 1.00 68.98  ? 111 PRO   A CG  1 
ATOM   658  C CD  . PRO   A 1 85  ? 165.019 134.047 123.399 1.00 63.02  ? 111 PRO   A CD  1 
ATOM   659  N N   . LEU   A 1 86  ? 164.678 138.753 123.815 1.00 65.94  ? 112 LEU   A N   1 
ATOM   660  C CA  . LEU   A 1 86  ? 163.832 139.936 123.946 1.00 69.84  ? 112 LEU   A CA  1 
ATOM   661  C C   . LEU   A 1 86  ? 162.848 140.059 122.788 1.00 77.06  ? 112 LEU   A C   1 
ATOM   662  O O   . LEU   A 1 86  ? 161.692 140.454 122.987 1.00 79.75  ? 112 LEU   A O   1 
ATOM   663  C CB  . LEU   A 1 86  ? 164.712 141.181 124.043 1.00 65.87  ? 112 LEU   A CB  1 
ATOM   664  C CG  . LEU   A 1 86  ? 164.035 142.531 124.286 1.00 72.20  ? 112 LEU   A CG  1 
ATOM   665  C CD1 . LEU   A 1 86  ? 163.222 142.525 125.566 1.00 76.51  ? 112 LEU   A CD1 1 
ATOM   666  C CD2 . LEU   A 1 86  ? 165.082 143.626 124.338 1.00 73.59  ? 112 LEU   A CD2 1 
ATOM   667  N N   . ASP   A 1 87  ? 163.290 139.741 121.569 1.00 75.14  ? 113 ASP   A N   1 
ATOM   668  C CA  . ASP   A 1 87  ? 162.416 139.879 120.407 1.00 68.61  ? 113 ASP   A CA  1 
ATOM   669  C C   . ASP   A 1 87  ? 161.215 138.945 120.501 1.00 72.06  ? 113 ASP   A C   1 
ATOM   670  O O   . ASP   A 1 87  ? 160.078 139.345 120.216 1.00 78.84  ? 113 ASP   A O   1 
ATOM   671  C CB  . ASP   A 1 87  ? 163.202 139.601 119.127 1.00 72.79  ? 113 ASP   A CB  1 
ATOM   672  C CG  . ASP   A 1 87  ? 164.447 140.452 119.010 1.00 84.06  ? 113 ASP   A CG  1 
ATOM   673  O OD1 . ASP   A 1 87  ? 164.432 141.599 119.503 1.00 87.96  ? 113 ASP   A OD1 1 
ATOM   674  O OD2 . ASP   A 1 87  ? 165.443 139.971 118.431 1.00 92.56  ? 113 ASP   A OD2 1 
ATOM   675  N N   . TRP   A 1 88  ? 161.447 137.696 120.906 1.00 65.60  ? 114 TRP   A N   1 
ATOM   676  C CA  . TRP   A 1 88  ? 160.342 136.756 121.039 1.00 66.65  ? 114 TRP   A CA  1 
ATOM   677  C C   . TRP   A 1 88  ? 159.403 137.174 122.162 1.00 68.14  ? 114 TRP   A C   1 
ATOM   678  O O   . TRP   A 1 88  ? 158.186 136.985 122.064 1.00 73.23  ? 114 TRP   A O   1 
ATOM   679  C CB  . TRP   A 1 88  ? 160.883 135.349 121.270 1.00 64.81  ? 114 TRP   A CB  1 
ATOM   680  C CG  . TRP   A 1 88  ? 161.752 134.870 120.149 1.00 64.28  ? 114 TRP   A CG  1 
ATOM   681  C CD1 . TRP   A 1 88  ? 163.111 134.922 120.089 1.00 68.54  ? 114 TRP   A CD1 1 
ATOM   682  C CD2 . TRP   A 1 88  ? 161.319 134.271 118.923 1.00 66.66  ? 114 TRP   A CD2 1 
ATOM   683  N NE1 . TRP   A 1 88  ? 163.554 134.390 118.905 1.00 70.09  ? 114 TRP   A NE1 1 
ATOM   684  C CE2 . TRP   A 1 88  ? 162.473 133.983 118.171 1.00 68.86  ? 114 TRP   A CE2 1 
ATOM   685  C CE3 . TRP   A 1 88  ? 160.068 133.949 118.389 1.00 72.32  ? 114 TRP   A CE3 1 
ATOM   686  C CZ2 . TRP   A 1 88  ? 162.415 133.389 116.915 1.00 72.48  ? 114 TRP   A CZ2 1 
ATOM   687  C CZ3 . TRP   A 1 88  ? 160.013 133.359 117.141 1.00 75.08  ? 114 TRP   A CZ3 1 
ATOM   688  C CH2 . TRP   A 1 88  ? 161.179 133.084 116.418 1.00 75.20  ? 114 TRP   A CH2 1 
ATOM   689  N N   . MET   A 1 89  ? 159.945 137.754 123.233 1.00 61.00  ? 115 MET   A N   1 
ATOM   690  C CA  . MET   A 1 89  ? 159.086 138.277 124.289 1.00 69.18  ? 115 MET   A CA  1 
ATOM   691  C C   . MET   A 1 89  ? 158.215 139.417 123.774 1.00 72.45  ? 115 MET   A C   1 
ATOM   692  O O   . MET   A 1 89  ? 157.028 139.504 124.115 1.00 77.22  ? 115 MET   A O   1 
ATOM   693  C CB  . MET   A 1 89  ? 159.934 138.733 125.474 1.00 67.37  ? 115 MET   A CB  1 
ATOM   694  C CG  . MET   A 1 89  ? 160.419 137.596 126.347 1.00 65.08  ? 115 MET   A CG  1 
ATOM   695  S SD  . MET   A 1 89  ? 159.109 136.938 127.389 1.00 76.20  ? 115 MET   A SD  1 
ATOM   696  C CE  . MET   A 1 89  ? 159.893 135.458 128.009 1.00 72.59  ? 115 MET   A CE  1 
ATOM   697  N N   . TYR   A 1 90  ? 158.783 140.305 122.954 1.00 65.10  ? 116 TYR   A N   1 
ATOM   698  C CA  . TYR   A 1 90  ? 157.976 141.373 122.371 1.00 61.42  ? 116 TYR   A CA  1 
ATOM   699  C C   . TYR   A 1 90  ? 156.891 140.803 121.468 1.00 63.46  ? 116 TYR   A C   1 
ATOM   700  O O   . TYR   A 1 90  ? 155.768 141.318 121.432 1.00 70.47  ? 116 TYR   A O   1 
ATOM   701  C CB  . TYR   A 1 90  ? 158.858 142.350 121.589 1.00 65.42  ? 116 TYR   A CB  1 
ATOM   702  C CG  . TYR   A 1 90  ? 159.362 143.560 122.360 1.00 67.78  ? 116 TYR   A CG  1 
ATOM   703  C CD1 . TYR   A 1 90  ? 158.492 144.397 123.047 1.00 71.75  ? 116 TYR   A CD1 1 
ATOM   704  C CD2 . TYR   A 1 90  ? 160.710 143.878 122.374 1.00 70.36  ? 116 TYR   A CD2 1 
ATOM   705  C CE1 . TYR   A 1 90  ? 158.953 145.498 123.737 1.00 75.80  ? 116 TYR   A CE1 1 
ATOM   706  C CE2 . TYR   A 1 90  ? 161.179 144.979 123.061 1.00 73.81  ? 116 TYR   A CE2 1 
ATOM   707  C CZ  . TYR   A 1 90  ? 160.296 145.785 123.739 1.00 77.52  ? 116 TYR   A CZ  1 
ATOM   708  O OH  . TYR   A 1 90  ? 160.760 146.883 124.424 1.00 86.57  ? 116 TYR   A OH  1 
ATOM   709  N N   . LEU   A 1 91  ? 157.207 139.735 120.735 1.00 62.66  ? 117 LEU   A N   1 
ATOM   710  C CA  . LEU   A 1 91  ? 156.184 139.072 119.930 1.00 62.49  ? 117 LEU   A CA  1 
ATOM   711  C C   . LEU   A 1 91  ? 155.078 138.504 120.813 1.00 67.39  ? 117 LEU   A C   1 
ATOM   712  O O   . LEU   A 1 91  ? 153.892 138.564 120.462 1.00 72.03  ? 117 LEU   A O   1 
ATOM   713  C CB  . LEU   A 1 91  ? 156.824 137.968 119.089 1.00 61.33  ? 117 LEU   A CB  1 
ATOM   714  C CG  . LEU   A 1 91  ? 155.918 137.176 118.145 1.00 62.17  ? 117 LEU   A CG  1 
ATOM   715  C CD1 . LEU   A 1 91  ? 155.288 138.079 117.101 1.00 66.13  ? 117 LEU   A CD1 1 
ATOM   716  C CD2 . LEU   A 1 91  ? 156.710 136.068 117.483 1.00 62.80  ? 117 LEU   A CD2 1 
ATOM   717  N N   . VAL   A 1 92  ? 155.451 137.943 121.965 1.00 66.01  ? 118 VAL   A N   1 
ATOM   718  C CA  . VAL   A 1 92  ? 154.459 137.393 122.887 1.00 60.53  ? 118 VAL   A CA  1 
ATOM   719  C C   . VAL   A 1 92  ? 153.540 138.498 123.398 1.00 61.05  ? 118 VAL   A C   1 
ATOM   720  O O   . VAL   A 1 92  ? 152.314 138.332 123.463 1.00 67.07  ? 118 VAL   A O   1 
ATOM   721  C CB  . VAL   A 1 92  ? 155.166 136.653 124.040 1.00 61.06  ? 118 VAL   A CB  1 
ATOM   722  C CG1 . VAL   A 1 92  ? 154.190 136.300 125.129 1.00 64.63  ? 118 VAL   A CG1 1 
ATOM   723  C CG2 . VAL   A 1 92  ? 155.826 135.381 123.533 1.00 61.97  ? 118 VAL   A CG2 1 
ATOM   724  N N   . TYR   A 1 93  ? 154.116 139.638 123.776 1.00 58.32  ? 119 TYR   A N   1 
ATOM   725  C CA  . TYR   A 1 93  ? 153.293 140.760 124.223 1.00 62.11  ? 119 TYR   A CA  1 
ATOM   726  C C   . TYR   A 1 93  ? 152.422 141.306 123.095 1.00 64.69  ? 119 TYR   A C   1 
ATOM   727  O O   . TYR   A 1 93  ? 151.306 141.778 123.344 1.00 69.17  ? 119 TYR   A O   1 
ATOM   728  C CB  . TYR   A 1 93  ? 154.175 141.866 124.798 1.00 71.70  ? 119 TYR   A CB  1 
ATOM   729  C CG  . TYR   A 1 93  ? 154.555 141.661 126.250 1.00 80.37  ? 119 TYR   A CG  1 
ATOM   730  C CD1 . TYR   A 1 93  ? 155.646 140.883 126.603 1.00 75.88  ? 119 TYR   A CD1 1 
ATOM   731  C CD2 . TYR   A 1 93  ? 153.826 142.255 127.266 1.00 83.95  ? 119 TYR   A CD2 1 
ATOM   732  C CE1 . TYR   A 1 93  ? 155.996 140.699 127.920 1.00 74.92  ? 119 TYR   A CE1 1 
ATOM   733  C CE2 . TYR   A 1 93  ? 154.170 142.075 128.586 1.00 83.13  ? 119 TYR   A CE2 1 
ATOM   734  C CZ  . TYR   A 1 93  ? 155.255 141.297 128.908 1.00 79.24  ? 119 TYR   A CZ  1 
ATOM   735  O OH  . TYR   A 1 93  ? 155.602 141.115 130.226 1.00 80.97  ? 119 TYR   A OH  1 
ATOM   736  N N   . THR   A 1 94  ? 152.911 141.262 121.855 1.00 61.93  ? 120 THR   A N   1 
ATOM   737  C CA  . THR   A 1 94  ? 152.076 141.651 120.723 1.00 57.99  ? 120 THR   A CA  1 
ATOM   738  C C   . THR   A 1 94  ? 150.879 140.720 120.585 1.00 61.45  ? 120 THR   A C   1 
ATOM   739  O O   . THR   A 1 94  ? 149.762 141.165 120.291 1.00 65.41  ? 120 THR   A O   1 
ATOM   740  C CB  . THR   A 1 94  ? 152.898 141.654 119.436 1.00 67.45  ? 120 THR   A CB  1 
ATOM   741  O OG1 . THR   A 1 94  ? 153.953 142.618 119.541 1.00 76.31  ? 120 THR   A OG1 1 
ATOM   742  C CG2 . THR   A 1 94  ? 152.019 141.995 118.241 1.00 66.35  ? 120 THR   A CG2 1 
ATOM   743  N N   . ILE   A 1 95  ? 151.099 139.418 120.780 1.00 61.86  ? 121 ILE   A N   1 
ATOM   744  C CA  . ILE   A 1 95  ? 149.989 138.467 120.754 1.00 56.49  ? 121 ILE   A CA  1 
ATOM   745  C C   . ILE   A 1 95  ? 149.004 138.776 121.876 1.00 56.95  ? 121 ILE   A C   1 
ATOM   746  O O   . ILE   A 1 95  ? 147.784 138.677 121.695 1.00 59.80  ? 121 ILE   A O   1 
ATOM   747  C CB  . ILE   A 1 95  ? 150.517 137.022 120.835 1.00 55.59  ? 121 ILE   A CB  1 
ATOM   748  C CG1 . ILE   A 1 95  ? 151.256 136.659 119.542 1.00 54.91  ? 121 ILE   A CG1 1 
ATOM   749  C CG2 . ILE   A 1 95  ? 149.370 136.045 121.099 1.00 58.13  ? 121 ILE   A CG2 1 
ATOM   750  C CD1 . ILE   A 1 95  ? 152.089 135.397 119.623 1.00 59.20  ? 121 ILE   A CD1 1 
ATOM   751  N N   . MET   A 1 96  ? 149.515 139.153 123.052 1.00 56.50  ? 122 MET   A N   1 
ATOM   752  C CA  . MET   A 1 96  ? 148.633 139.566 124.144 1.00 55.28  ? 122 MET   A CA  1 
ATOM   753  C C   . MET   A 1 96  ? 147.769 140.752 123.737 1.00 55.62  ? 122 MET   A C   1 
ATOM   754  O O   . MET   A 1 96  ? 146.556 140.764 123.981 1.00 62.27  ? 122 MET   A O   1 
ATOM   755  C CB  . MET   A 1 96  ? 149.445 139.943 125.383 1.00 61.61  ? 122 MET   A CB  1 
ATOM   756  C CG  . MET   A 1 96  ? 149.903 138.782 126.225 1.00 65.03  ? 122 MET   A CG  1 
ATOM   757  S SD  . MET   A 1 96  ? 150.883 139.273 127.659 1.00 83.60  ? 122 MET   A SD  1 
ATOM   758  C CE  . MET   A 1 96  ? 149.722 140.285 128.569 1.00 73.56  ? 122 MET   A CE  1 
ATOM   759  N N   . PHE   A 1 97  ? 148.386 141.768 123.134 1.00 52.64  ? 123 PHE   A N   1 
ATOM   760  C CA  . PHE   A 1 97  ? 147.645 142.960 122.732 1.00 52.29  ? 123 PHE   A CA  1 
ATOM   761  C C   . PHE   A 1 97  ? 146.588 142.625 121.686 1.00 62.04  ? 123 PHE   A C   1 
ATOM   762  O O   . PHE   A 1 97  ? 145.455 143.123 121.753 1.00 67.59  ? 123 PHE   A O   1 
ATOM   763  C CB  . PHE   A 1 97  ? 148.619 144.010 122.201 1.00 58.71  ? 123 PHE   A CB  1 
ATOM   764  C CG  . PHE   A 1 97  ? 147.963 145.284 121.760 1.00 61.57  ? 123 PHE   A CG  1 
ATOM   765  C CD1 . PHE   A 1 97  ? 147.649 146.268 122.674 1.00 60.35  ? 123 PHE   A CD1 1 
ATOM   766  C CD2 . PHE   A 1 97  ? 147.680 145.506 120.424 1.00 68.12  ? 123 PHE   A CD2 1 
ATOM   767  C CE1 . PHE   A 1 97  ? 147.055 147.443 122.269 1.00 69.96  ? 123 PHE   A CE1 1 
ATOM   768  C CE2 . PHE   A 1 97  ? 147.087 146.679 120.014 1.00 73.74  ? 123 PHE   A CE2 1 
ATOM   769  C CZ  . PHE   A 1 97  ? 146.773 147.648 120.937 1.00 76.33  ? 123 PHE   A CZ  1 
ATOM   770  N N   . LEU   A 1 98  ? 146.943 141.789 120.707 1.00 63.14  ? 124 LEU   A N   1 
ATOM   771  C CA  . LEU   A 1 98  ? 145.975 141.395 119.687 1.00 57.39  ? 124 LEU   A CA  1 
ATOM   772  C C   . LEU   A 1 98  ? 144.811 140.629 120.299 1.00 55.29  ? 124 LEU   A C   1 
ATOM   773  O O   . LEU   A 1 98  ? 143.650 140.860 119.939 1.00 59.48  ? 124 LEU   A O   1 
ATOM   774  C CB  . LEU   A 1 98  ? 146.651 140.555 118.604 1.00 56.64  ? 124 LEU   A CB  1 
ATOM   775  C CG  . LEU   A 1 98  ? 147.120 141.315 117.362 1.00 60.86  ? 124 LEU   A CG  1 
ATOM   776  C CD1 . LEU   A 1 98  ? 148.204 142.327 117.693 1.00 62.69  ? 124 LEU   A CD1 1 
ATOM   777  C CD2 . LEU   A 1 98  ? 147.610 140.337 116.313 1.00 61.19  ? 124 LEU   A CD2 1 
ATOM   778  N N   . GLY   A 1 99  ? 145.099 139.709 121.221 1.00 56.16  ? 125 GLY   A N   1 
ATOM   779  C CA  . GLY   A 1 99  ? 144.029 138.992 121.892 1.00 59.06  ? 125 GLY   A CA  1 
ATOM   780  C C   . GLY   A 1 99  ? 143.120 139.912 122.682 1.00 56.49  ? 125 GLY   A C   1 
ATOM   781  O O   . GLY   A 1 99  ? 141.897 139.746 122.680 1.00 61.31  ? 125 GLY   A O   1 
ATOM   782  N N   . ALA   A 1 100 ? 143.702 140.895 123.369 1.00 50.69  ? 126 ALA   A N   1 
ATOM   783  C CA  . ALA   A 1 100 ? 142.892 141.825 124.145 1.00 49.75  ? 126 ALA   A CA  1 
ATOM   784  C C   . ALA   A 1 100 ? 141.992 142.658 123.242 1.00 59.23  ? 126 ALA   A C   1 
ATOM   785  O O   . ALA   A 1 100 ? 140.809 142.859 123.546 1.00 69.37  ? 126 ALA   A O   1 
ATOM   786  C CB  . ALA   A 1 100 ? 143.791 142.725 124.988 1.00 59.89  ? 126 ALA   A CB  1 
ATOM   787  N N   . LEU   A 1 101 ? 142.529 143.142 122.118 1.00 61.74  ? 127 LEU   A N   1 
ATOM   788  C CA  . LEU   A 1 101 ? 141.696 143.889 121.176 1.00 58.98  ? 127 LEU   A CA  1 
ATOM   789  C C   . LEU   A 1 101 ? 140.586 143.015 120.605 1.00 62.94  ? 127 LEU   A C   1 
ATOM   790  O O   . LEU   A 1 101 ? 139.443 143.468 120.460 1.00 67.08  ? 127 LEU   A O   1 
ATOM   791  C CB  . LEU   A 1 101 ? 142.545 144.465 120.042 1.00 60.39  ? 127 LEU   A CB  1 
ATOM   792  C CG  . LEU   A 1 101 ? 143.044 145.905 120.174 1.00 70.71  ? 127 LEU   A CG  1 
ATOM   793  C CD1 . LEU   A 1 101 ? 143.936 146.248 118.995 1.00 74.41  ? 127 LEU   A CD1 1 
ATOM   794  C CD2 . LEU   A 1 101 ? 141.894 146.897 120.263 1.00 71.22  ? 127 LEU   A CD2 1 
ATOM   795  N N   . GLY   A 1 102 ? 140.907 141.768 120.257 1.00 61.33  ? 128 GLY   A N   1 
ATOM   796  C CA  . GLY   A 1 102 ? 139.886 140.870 119.741 1.00 57.66  ? 128 GLY   A CA  1 
ATOM   797  C C   . GLY   A 1 102 ? 138.778 140.612 120.742 1.00 56.88  ? 128 GLY   A C   1 
ATOM   798  O O   . GLY   A 1 102 ? 137.600 140.569 120.381 1.00 65.64  ? 128 GLY   A O   1 
ATOM   799  N N   . MET   A 1 103 ? 139.140 140.431 122.013 1.00 55.11  ? 129 MET   A N   1 
ATOM   800  C CA  . MET   A 1 103 ? 138.124 140.281 123.050 1.00 57.64  ? 129 MET   A CA  1 
ATOM   801  C C   . MET   A 1 103 ? 137.288 141.546 123.181 1.00 60.28  ? 129 MET   A C   1 
ATOM   802  O O   . MET   A 1 103 ? 136.071 141.475 123.392 1.00 68.77  ? 129 MET   A O   1 
ATOM   803  C CB  . MET   A 1 103 ? 138.779 139.938 124.385 1.00 63.38  ? 129 MET   A CB  1 
ATOM   804  C CG  . MET   A 1 103 ? 139.290 138.510 124.473 1.00 68.97  ? 129 MET   A CG  1 
ATOM   805  S SD  . MET   A 1 103 ? 140.130 138.145 126.026 1.00 80.30  ? 129 MET   A SD  1 
ATOM   806  C CE  . MET   A 1 103 ? 138.803 138.371 127.203 1.00 64.53  ? 129 MET   A CE  1 
ATOM   807  N N   . MET   A 1 104 ? 137.925 142.713 123.074 1.00 58.26  ? 130 MET   A N   1 
ATOM   808  C CA  . MET   A 1 104 ? 137.187 143.967 123.183 1.00 58.83  ? 130 MET   A CA  1 
ATOM   809  C C   . MET   A 1 104 ? 136.162 144.102 122.064 1.00 68.72  ? 130 MET   A C   1 
ATOM   810  O O   . MET   A 1 104 ? 135.008 144.473 122.311 1.00 70.92  ? 130 MET   A O   1 
ATOM   811  C CB  . MET   A 1 104 ? 138.159 145.144 123.156 1.00 60.62  ? 130 MET   A CB  1 
ATOM   812  C CG  . MET   A 1 104 ? 137.538 146.484 123.512 1.00 63.89  ? 130 MET   A CG  1 
ATOM   813  S SD  . MET   A 1 104 ? 138.691 147.851 123.311 1.00 85.84  ? 130 MET   A SD  1 
ATOM   814  C CE  . MET   A 1 104 ? 138.755 147.980 121.528 1.00 72.44  ? 130 MET   A CE  1 
ATOM   815  N N   . LEU   A 1 105 ? 136.560 143.800 120.829 1.00 67.10  ? 131 LEU   A N   1 
ATOM   816  C CA  . LEU   A 1 105 ? 135.666 143.902 119.682 1.00 60.35  ? 131 LEU   A CA  1 
ATOM   817  C C   . LEU   A 1 105 ? 134.879 142.627 119.415 1.00 60.88  ? 131 LEU   A C   1 
ATOM   818  O O   . LEU   A 1 105 ? 133.990 142.640 118.557 1.00 66.22  ? 131 LEU   A O   1 
ATOM   819  C CB  . LEU   A 1 105 ? 136.459 144.269 118.425 1.00 59.15  ? 131 LEU   A CB  1 
ATOM   820  C CG  . LEU   A 1 105 ? 137.262 145.568 118.476 1.00 65.46  ? 131 LEU   A CG  1 
ATOM   821  C CD1 . LEU   A 1 105 ? 138.076 145.724 117.206 1.00 69.29  ? 131 LEU   A CD1 1 
ATOM   822  C CD2 . LEU   A 1 105 ? 136.354 146.770 118.677 1.00 68.44  ? 131 LEU   A CD2 1 
ATOM   823  N N   . GLY   A 1 106 ? 135.172 141.537 120.115 1.00 59.25  ? 132 GLY   A N   1 
ATOM   824  C CA  . GLY   A 1 106 ? 134.438 140.302 119.896 1.00 51.95  ? 132 GLY   A CA  1 
ATOM   825  C C   . GLY   A 1 106 ? 134.637 139.720 118.515 1.00 55.88  ? 132 GLY   A C   1 
ATOM   826  O O   . GLY   A 1 106 ? 133.684 139.201 117.921 1.00 66.02  ? 132 GLY   A O   1 
ATOM   827  N N   . LEU   A 1 107 ? 135.859 139.794 117.991 1.00 61.01  ? 133 LEU   A N   1 
ATOM   828  C CA  . LEU   A 1 107 ? 136.208 139.277 116.672 1.00 63.27  ? 133 LEU   A CA  1 
ATOM   829  C C   . LEU   A 1 107 ? 137.082 138.043 116.853 1.00 60.90  ? 133 LEU   A C   1 
ATOM   830  O O   . LEU   A 1 107 ? 138.192 138.142 117.387 1.00 67.81  ? 133 LEU   A O   1 
ATOM   831  C CB  . LEU   A 1 107 ? 136.935 140.341 115.850 1.00 59.51  ? 133 LEU   A CB  1 
ATOM   832  C CG  . LEU   A 1 107 ? 137.321 139.990 114.414 1.00 61.76  ? 133 LEU   A CG  1 
ATOM   833  C CD1 . LEU   A 1 107 ? 136.097 139.667 113.575 1.00 67.85  ? 133 LEU   A CD1 1 
ATOM   834  C CD2 . LEU   A 1 107 ? 138.102 141.135 113.798 1.00 62.09  ? 133 LEU   A CD2 1 
ATOM   835  N N   . CYS   A 1 108 ? 136.590 136.892 116.390 1.00 52.46  ? 134 CYS   A N   1 
ATOM   836  C CA  . CYS   A 1 108 ? 137.226 135.601 116.643 1.00 55.09  ? 134 CYS   A CA  1 
ATOM   837  C C   . CYS   A 1 108 ? 137.447 135.418 118.145 1.00 64.13  ? 134 CYS   A C   1 
ATOM   838  O O   . CYS   A 1 108 ? 138.575 135.316 118.633 1.00 72.60  ? 134 CYS   A O   1 
ATOM   839  C CB  . CYS   A 1 108 ? 138.536 135.468 115.862 1.00 63.41  ? 134 CYS   A CB  1 
ATOM   840  S SG  . CYS   A 1 108 ? 138.329 135.457 114.068 1.00 84.37  ? 134 CYS   A SG  1 
ATOM   841  N N   . TYR   A 1 109 ? 136.326 135.394 118.870 1.00 57.42  ? 135 TYR   A N   1 
ATOM   842  C CA  . TYR   A 1 109 ? 136.358 135.574 120.318 1.00 56.86  ? 135 TYR   A CA  1 
ATOM   843  C C   . TYR   A 1 109 ? 137.155 134.481 121.022 1.00 64.35  ? 135 TYR   A C   1 
ATOM   844  O O   . TYR   A 1 109 ? 137.955 134.774 121.916 1.00 74.58  ? 135 TYR   A O   1 
ATOM   845  C CB  . TYR   A 1 109 ? 134.934 135.620 120.862 1.00 58.82  ? 135 TYR   A CB  1 
ATOM   846  C CG  . TYR   A 1 109 ? 134.870 135.873 122.344 1.00 56.72  ? 135 TYR   A CG  1 
ATOM   847  C CD1 . TYR   A 1 109 ? 135.137 137.127 122.862 1.00 59.37  ? 135 TYR   A CD1 1 
ATOM   848  C CD2 . TYR   A 1 109 ? 134.538 134.859 123.225 1.00 61.33  ? 135 TYR   A CD2 1 
ATOM   849  C CE1 . TYR   A 1 109 ? 135.081 137.363 124.217 1.00 63.68  ? 135 TYR   A CE1 1 
ATOM   850  C CE2 . TYR   A 1 109 ? 134.476 135.086 124.581 1.00 65.40  ? 135 TYR   A CE2 1 
ATOM   851  C CZ  . TYR   A 1 109 ? 134.747 136.340 125.071 1.00 65.02  ? 135 TYR   A CZ  1 
ATOM   852  O OH  . TYR   A 1 109 ? 134.687 136.571 126.425 1.00 71.71  ? 135 TYR   A OH  1 
ATOM   853  N N   . ARG   A 1 110 ? 136.945 133.217 120.650 1.00 55.00  ? 136 ARG   A N   1 
ATOM   854  C CA  . ARG   A 1 110 ? 137.641 132.138 121.347 1.00 61.54  ? 136 ARG   A CA  1 
ATOM   855  C C   . ARG   A 1 110 ? 139.141 132.178 121.075 1.00 66.44  ? 136 ARG   A C   1 
ATOM   856  O O   . ARG   A 1 110 ? 139.951 131.975 121.991 1.00 67.55  ? 136 ARG   A O   1 
ATOM   857  C CB  . ARG   A 1 110 ? 137.045 130.785 120.959 1.00 62.82  ? 136 ARG   A CB  1 
ATOM   858  C CG  . ARG   A 1 110 ? 136.017 130.239 121.959 1.00 72.28  ? 136 ARG   A CG  1 
ATOM   859  C CD  . ARG   A 1 110 ? 134.879 131.221 122.266 1.00 79.41  ? 136 ARG   A CD  1 
ATOM   860  N NE  . ARG   A 1 110 ? 133.960 130.698 123.275 1.00 74.83  ? 136 ARG   A NE  1 
ATOM   861  C CZ  . ARG   A 1 110 ? 132.828 130.047 123.036 1.00 75.48  ? 136 ARG   A CZ  1 
ATOM   862  N NH1 . ARG   A 1 110 ? 132.410 129.794 121.804 1.00 82.30  ? 136 ARG   A NH1 1 
ATOM   863  N NH2 . ARG   A 1 110 ? 132.091 129.636 124.063 1.00 76.10  ? 136 ARG   A NH2 1 
ATOM   864  N N   . ILE   A 1 111 ? 139.532 132.455 119.831 1.00 59.18  ? 137 ILE   A N   1 
ATOM   865  C CA  . ILE   A 1 111 ? 140.952 132.574 119.519 1.00 55.02  ? 137 ILE   A CA  1 
ATOM   866  C C   . ILE   A 1 111 ? 141.554 133.760 120.258 1.00 58.97  ? 137 ILE   A C   1 
ATOM   867  O O   . ILE   A 1 111 ? 142.681 133.685 120.763 1.00 64.77  ? 137 ILE   A O   1 
ATOM   868  C CB  . ILE   A 1 111 ? 141.162 132.683 117.998 1.00 54.30  ? 137 ILE   A CB  1 
ATOM   869  C CG1 . ILE   A 1 111 ? 140.793 131.361 117.315 1.00 55.93  ? 137 ILE   A CG1 1 
ATOM   870  C CG2 . ILE   A 1 111 ? 142.611 133.072 117.687 1.00 58.82  ? 137 ILE   A CG2 1 
ATOM   871  C CD1 . ILE   A 1 111 ? 140.629 131.463 115.812 1.00 63.13  ? 137 ILE   A CD1 1 
ATOM   872  N N   . SER   A 1 112 ? 140.818 134.870 120.337 1.00 55.10  ? 138 SER   A N   1 
ATOM   873  C CA  . SER   A 1 112 ? 141.306 136.029 121.077 1.00 57.47  ? 138 SER   A CA  1 
ATOM   874  C C   . SER   A 1 112 ? 141.512 135.693 122.547 1.00 58.16  ? 138 SER   A C   1 
ATOM   875  O O   . SER   A 1 112 ? 142.535 136.058 123.141 1.00 61.60  ? 138 SER   A O   1 
ATOM   876  C CB  . SER   A 1 112 ? 140.327 137.192 120.929 1.00 57.33  ? 138 SER   A CB  1 
ATOM   877  O OG  . SER   A 1 112 ? 140.124 137.517 119.566 1.00 59.79  ? 138 SER   A OG  1 
ATOM   878  N N   . CYS   A 1 113 ? 140.551 134.988 123.148 1.00 57.88  ? 139 CYS   A N   1 
ATOM   879  C CA  . CYS   A 1 113 ? 140.670 134.618 124.553 1.00 62.80  ? 139 CYS   A CA  1 
ATOM   880  C C   . CYS   A 1 113 ? 141.865 133.703 124.784 1.00 63.60  ? 139 CYS   A C   1 
ATOM   881  O O   . CYS   A 1 113 ? 142.606 133.880 125.755 1.00 69.09  ? 139 CYS   A O   1 
ATOM   882  C CB  . CYS   A 1 113 ? 139.383 133.948 125.031 1.00 65.53  ? 139 CYS   A CB  1 
ATOM   883  S SG  . CYS   A 1 113 ? 138.004 135.081 125.282 1.00 76.04  ? 139 CYS   A SG  1 
ATOM   884  N N   . VAL   A 1 114 ? 142.074 132.722 123.903 1.00 53.79  ? 140 VAL   A N   1 
ATOM   885  C CA  . VAL   A 1 114 ? 143.206 131.812 124.068 1.00 50.75  ? 140 VAL   A CA  1 
ATOM   886  C C   . VAL   A 1 114 ? 144.526 132.564 123.925 1.00 56.60  ? 140 VAL   A C   1 
ATOM   887  O O   . VAL   A 1 114 ? 145.470 132.362 124.710 1.00 60.81  ? 140 VAL   A O   1 
ATOM   888  C CB  . VAL   A 1 114 ? 143.101 130.651 123.062 1.00 47.98  ? 140 VAL   A CB  1 
ATOM   889  C CG1 . VAL   A 1 114 ? 144.381 129.832 123.043 1.00 54.70  ? 140 VAL   A CG1 1 
ATOM   890  C CG2 . VAL   A 1 114 ? 141.919 129.760 123.404 1.00 56.79  ? 140 VAL   A CG2 1 
ATOM   891  N N   . LEU   A 1 115 ? 144.619 133.431 122.911 1.00 55.72  ? 141 LEU   A N   1 
ATOM   892  C CA  . LEU   A 1 115 ? 145.854 134.163 122.659 1.00 54.69  ? 141 LEU   A CA  1 
ATOM   893  C C   . LEU   A 1 115 ? 146.159 135.153 123.771 1.00 54.82  ? 141 LEU   A C   1 
ATOM   894  O O   . LEU   A 1 115 ? 147.327 135.486 123.993 1.00 63.60  ? 141 LEU   A O   1 
ATOM   895  C CB  . LEU   A 1 115 ? 145.768 134.891 121.317 1.00 54.57  ? 141 LEU   A CB  1 
ATOM   896  C CG  . LEU   A 1 115 ? 145.768 134.030 120.050 1.00 58.09  ? 141 LEU   A CG  1 
ATOM   897  C CD1 . LEU   A 1 115 ? 145.489 134.891 118.833 1.00 57.26  ? 141 LEU   A CD1 1 
ATOM   898  C CD2 . LEU   A 1 115 ? 147.081 133.285 119.880 1.00 57.68  ? 141 LEU   A CD2 1 
ATOM   899  N N   . PHE   A 1 116 ? 145.133 135.668 124.448 1.00 50.77  ? 142 PHE   A N   1 
ATOM   900  C CA  . PHE   A 1 116 ? 145.381 136.482 125.631 1.00 48.73  ? 142 PHE   A CA  1 
ATOM   901  C C   . PHE   A 1 116 ? 145.727 135.629 126.843 1.00 50.01  ? 142 PHE   A C   1 
ATOM   902  O O   . PHE   A 1 116 ? 146.531 136.048 127.682 1.00 60.95  ? 142 PHE   A O   1 
ATOM   903  C CB  . PHE   A 1 116 ? 144.169 137.351 125.945 1.00 51.52  ? 142 PHE   A CB  1 
ATOM   904  C CG  . PHE   A 1 116 ? 144.393 138.309 127.078 1.00 53.92  ? 142 PHE   A CG  1 
ATOM   905  C CD1 . PHE   A 1 116 ? 145.058 139.502 126.869 1.00 60.00  ? 142 PHE   A CD1 1 
ATOM   906  C CD2 . PHE   A 1 116 ? 143.939 138.020 128.350 1.00 56.92  ? 142 PHE   A CD2 1 
ATOM   907  C CE1 . PHE   A 1 116 ? 145.265 140.383 127.906 1.00 62.52  ? 142 PHE   A CE1 1 
ATOM   908  C CE2 . PHE   A 1 116 ? 144.144 138.900 129.387 1.00 55.81  ? 142 PHE   A CE2 1 
ATOM   909  C CZ  . PHE   A 1 116 ? 144.807 140.081 129.165 1.00 61.15  ? 142 PHE   A CZ  1 
ATOM   910  N N   . LEU   A 1 117 ? 145.135 134.441 126.950 1.00 50.41  ? 143 LEU   A N   1 
ATOM   911  C CA  . LEU   A 1 117 ? 145.240 133.662 128.176 1.00 53.74  ? 143 LEU   A CA  1 
ATOM   912  C C   . LEU   A 1 117 ? 146.612 133.023 128.316 1.00 56.61  ? 143 LEU   A C   1 
ATOM   913  O O   . LEU   A 1 117 ? 147.260 133.151 129.361 1.00 56.99  ? 143 LEU   A O   1 
ATOM   914  C CB  . LEU   A 1 117 ? 144.150 132.591 128.187 1.00 54.07  ? 143 LEU   A CB  1 
ATOM   915  C CG  . LEU   A 1 117 ? 144.015 131.722 129.434 1.00 53.06  ? 143 LEU   A CG  1 
ATOM   916  C CD1 . LEU   A 1 117 ? 143.493 132.545 130.594 1.00 56.99  ? 143 LEU   A CD1 1 
ATOM   917  C CD2 . LEU   A 1 117 ? 143.101 130.544 129.158 1.00 53.84  ? 143 LEU   A CD2 1 
ATOM   918  N N   . LEU   A 1 118 ? 147.066 132.307 127.276 1.00 55.91  ? 144 LEU   A N   1 
ATOM   919  C CA  . LEU   A 1 118 ? 148.292 131.519 127.427 1.00 52.69  ? 144 LEU   A CA  1 
ATOM   920  C C   . LEU   A 1 118 ? 149.507 132.409 127.672 1.00 56.68  ? 144 LEU   A C   1 
ATOM   921  O O   . LEU   A 1 118 ? 150.249 132.168 128.644 1.00 62.74  ? 144 LEU   A O   1 
ATOM   922  C CB  . LEU   A 1 118 ? 148.469 130.594 126.219 1.00 48.52  ? 144 LEU   A CB  1 
ATOM   923  C CG  . LEU   A 1 118 ? 147.749 129.245 126.240 1.00 53.40  ? 144 LEU   A CG  1 
ATOM   924  C CD1 . LEU   A 1 118 ? 146.264 129.412 126.485 1.00 54.08  ? 144 LEU   A CD1 1 
ATOM   925  C CD2 . LEU   A 1 118 ? 147.990 128.512 124.933 1.00 57.06  ? 144 LEU   A CD2 1 
ATOM   926  N N   . PRO   A 1 119 ? 149.769 133.441 126.862 1.00 51.35  ? 145 PRO   A N   1 
ATOM   927  C CA  . PRO   A 1 119 ? 150.837 134.393 127.200 1.00 50.58  ? 145 PRO   A CA  1 
ATOM   928  C C   . PRO   A 1 119 ? 150.716 135.038 128.567 1.00 57.09  ? 145 PRO   A C   1 
ATOM   929  O O   . PRO   A 1 119 ? 151.742 135.238 129.232 1.00 63.49  ? 145 PRO   A O   1 
ATOM   930  C CB  . PRO   A 1 119 ? 150.692 135.441 126.099 1.00 48.60  ? 145 PRO   A CB  1 
ATOM   931  C CG  . PRO   A 1 119 ? 150.286 134.671 124.932 1.00 52.71  ? 145 PRO   A CG  1 
ATOM   932  C CD  . PRO   A 1 119 ? 149.377 133.581 125.449 1.00 53.97  ? 145 PRO   A CD  1 
ATOM   933  N N   . TYR   A 1 120 ? 149.506 135.397 128.997 1.00 56.00  ? 146 TYR   A N   1 
ATOM   934  C CA  . TYR   A 1 120 ? 149.358 136.088 130.273 1.00 55.01  ? 146 TYR   A CA  1 
ATOM   935  C C   . TYR   A 1 120 ? 149.818 135.208 131.424 1.00 58.31  ? 146 TYR   A C   1 
ATOM   936  O O   . TYR   A 1 120 ? 150.570 135.653 132.298 1.00 63.65  ? 146 TYR   A O   1 
ATOM   937  C CB  . TYR   A 1 120 ? 147.907 136.517 130.477 1.00 54.70  ? 146 TYR   A CB  1 
ATOM   938  C CG  . TYR   A 1 120 ? 147.694 137.359 131.714 1.00 50.09  ? 146 TYR   A CG  1 
ATOM   939  C CD1 . TYR   A 1 120 ? 147.832 138.735 131.669 1.00 58.45  ? 146 TYR   A CD1 1 
ATOM   940  C CD2 . TYR   A 1 120 ? 147.349 136.779 132.922 1.00 52.16  ? 146 TYR   A CD2 1 
ATOM   941  C CE1 . TYR   A 1 120 ? 147.637 139.506 132.792 1.00 62.08  ? 146 TYR   A CE1 1 
ATOM   942  C CE2 . TYR   A 1 120 ? 147.154 137.543 134.049 1.00 59.35  ? 146 TYR   A CE2 1 
ATOM   943  C CZ  . TYR   A 1 120 ? 147.298 138.904 133.978 1.00 63.52  ? 146 TYR   A CZ  1 
ATOM   944  O OH  . TYR   A 1 120 ? 147.102 139.671 135.100 1.00 75.40  ? 146 TYR   A OH  1 
ATOM   945  N N   . TRP   A 1 121 ? 149.382 133.950 131.440 1.00 54.19  ? 147 TRP   A N   1 
ATOM   946  C CA  . TRP   A 1 121 ? 149.808 133.053 132.504 1.00 54.32  ? 147 TRP   A CA  1 
ATOM   947  C C   . TRP   A 1 121 ? 151.283 132.698 132.380 1.00 56.13  ? 147 TRP   A C   1 
ATOM   948  O O   . TRP   A 1 121 ? 151.956 132.512 133.403 1.00 65.69  ? 147 TRP   A O   1 
ATOM   949  C CB  . TRP   A 1 121 ? 148.938 131.799 132.515 1.00 53.21  ? 147 TRP   A CB  1 
ATOM   950  C CG  . TRP   A 1 121 ? 147.578 132.062 133.076 1.00 53.62  ? 147 TRP   A CG  1 
ATOM   951  C CD1 . TRP   A 1 121 ? 146.427 132.270 132.377 1.00 57.72  ? 147 TRP   A CD1 1 
ATOM   952  C CD2 . TRP   A 1 121 ? 147.231 132.169 134.461 1.00 53.90  ? 147 TRP   A CD2 1 
ATOM   953  N NE1 . TRP   A 1 121 ? 145.382 132.492 133.241 1.00 58.14  ? 147 TRP   A NE1 1 
ATOM   954  C CE2 . TRP   A 1 121 ? 145.851 132.436 134.526 1.00 55.41  ? 147 TRP   A CE2 1 
ATOM   955  C CE3 . TRP   A 1 121 ? 147.953 132.062 135.652 1.00 58.52  ? 147 TRP   A CE3 1 
ATOM   956  C CZ2 . TRP   A 1 121 ? 145.179 132.595 135.732 1.00 61.35  ? 147 TRP   A CZ2 1 
ATOM   957  C CZ3 . TRP   A 1 121 ? 147.285 132.220 136.848 1.00 60.95  ? 147 TRP   A CZ3 1 
ATOM   958  C CH2 . TRP   A 1 121 ? 145.912 132.484 136.880 1.00 62.01  ? 147 TRP   A CH2 1 
ATOM   959  N N   . TYR   A 1 122 ? 151.812 132.613 131.155 1.00 49.91  ? 148 TYR   A N   1 
ATOM   960  C CA  . TYR   A 1 122 ? 153.246 132.378 131.008 1.00 54.88  ? 148 TYR   A CA  1 
ATOM   961  C C   . TYR   A 1 122 ? 154.050 133.508 131.639 1.00 62.29  ? 148 TYR   A C   1 
ATOM   962  O O   . TYR   A 1 122 ? 155.032 133.267 132.350 1.00 68.78  ? 148 TYR   A O   1 
ATOM   963  C CB  . TYR   A 1 122 ? 153.618 132.221 129.534 1.00 56.97  ? 148 TYR   A CB  1 
ATOM   964  C CG  . TYR   A 1 122 ? 155.101 132.014 129.313 1.00 59.06  ? 148 TYR   A CG  1 
ATOM   965  C CD1 . TYR   A 1 122 ? 155.681 130.768 129.491 1.00 62.96  ? 148 TYR   A CD1 1 
ATOM   966  C CD2 . TYR   A 1 122 ? 155.921 133.065 128.931 1.00 60.88  ? 148 TYR   A CD2 1 
ATOM   967  C CE1 . TYR   A 1 122 ? 157.033 130.575 129.294 1.00 65.27  ? 148 TYR   A CE1 1 
ATOM   968  C CE2 . TYR   A 1 122 ? 157.273 132.879 128.733 1.00 64.72  ? 148 TYR   A CE2 1 
ATOM   969  C CZ  . TYR   A 1 122 ? 157.823 131.634 128.917 1.00 67.62  ? 148 TYR   A CZ  1 
ATOM   970  O OH  . TYR   A 1 122 ? 159.170 131.443 128.719 1.00 75.83  ? 148 TYR   A OH  1 
ATOM   971  N N   . VAL   A 1 123 ? 153.647 134.754 131.387 1.00 61.68  ? 149 VAL   A N   1 
ATOM   972  C CA  . VAL   A 1 123 ? 154.347 135.892 131.977 1.00 57.73  ? 149 VAL   A CA  1 
ATOM   973  C C   . VAL   A 1 123 ? 154.142 135.923 133.486 1.00 60.26  ? 149 VAL   A C   1 
ATOM   974  O O   . VAL   A 1 123 ? 155.063 136.249 134.244 1.00 66.75  ? 149 VAL   A O   1 
ATOM   975  C CB  . VAL   A 1 123 ? 153.888 137.204 131.314 1.00 58.57  ? 149 VAL   A CB  1 
ATOM   976  C CG1 . VAL   A 1 123 ? 154.423 138.411 132.074 1.00 62.49  ? 149 VAL   A CG1 1 
ATOM   977  C CG2 . VAL   A 1 123 ? 154.343 137.249 129.867 1.00 62.56  ? 149 VAL   A CG2 1 
ATOM   978  N N   . PHE   A 1 124 ? 152.932 135.598 133.947 1.00 58.89  ? 150 PHE   A N   1 
ATOM   979  C CA  . PHE   A 1 124 ? 152.637 135.649 135.375 1.00 62.61  ? 150 PHE   A CA  1 
ATOM   980  C C   . PHE   A 1 124 ? 153.486 134.651 136.152 1.00 63.75  ? 150 PHE   A C   1 
ATOM   981  O O   . PHE   A 1 124 ? 154.008 134.974 137.226 1.00 70.63  ? 150 PHE   A O   1 
ATOM   982  C CB  . PHE   A 1 124 ? 151.150 135.383 135.602 1.00 60.33  ? 150 PHE   A CB  1 
ATOM   983  C CG  . PHE   A 1 124 ? 150.712 135.547 137.026 1.00 60.69  ? 150 PHE   A CG  1 
ATOM   984  C CD1 . PHE   A 1 124 ? 150.474 136.804 137.548 1.00 65.03  ? 150 PHE   A CD1 1 
ATOM   985  C CD2 . PHE   A 1 124 ? 150.521 134.446 137.837 1.00 63.23  ? 150 PHE   A CD2 1 
ATOM   986  C CE1 . PHE   A 1 124 ? 150.066 136.959 138.853 1.00 71.86  ? 150 PHE   A CE1 1 
ATOM   987  C CE2 . PHE   A 1 124 ? 150.113 134.596 139.145 1.00 70.75  ? 150 PHE   A CE2 1 
ATOM   988  C CZ  . PHE   A 1 124 ? 149.884 135.855 139.653 1.00 74.20  ? 150 PHE   A CZ  1 
ATOM   989  N N   . LEU   A 1 125 ? 153.639 133.434 135.627 1.00 57.96  ? 151 LEU   A N   1 
ATOM   990  C CA  . LEU   A 1 125 ? 154.434 132.425 136.313 1.00 55.82  ? 151 LEU   A CA  1 
ATOM   991  C C   . LEU   A 1 125 ? 155.934 132.649 136.170 1.00 66.30  ? 151 LEU   A C   1 
ATOM   992  O O   . LEU   A 1 125 ? 156.707 132.059 136.931 1.00 73.33  ? 151 LEU   A O   1 
ATOM   993  C CB  . LEU   A 1 125 ? 154.085 131.031 135.788 1.00 54.20  ? 151 LEU   A CB  1 
ATOM   994  C CG  . LEU   A 1 125 ? 152.646 130.546 135.968 1.00 59.45  ? 151 LEU   A CG  1 
ATOM   995  C CD1 . LEU   A 1 125 ? 152.479 129.178 135.336 1.00 60.09  ? 151 LEU   A CD1 1 
ATOM   996  C CD2 . LEU   A 1 125 ? 152.251 130.502 137.434 1.00 66.18  ? 151 LEU   A CD2 1 
ATOM   997  N N   . LEU   A 1 126 ? 156.367 133.476 135.216 1.00 67.30  ? 152 LEU   A N   1 
ATOM   998  C CA  . LEU   A 1 126 ? 157.796 133.622 134.958 1.00 65.81  ? 152 LEU   A CA  1 
ATOM   999  C C   . LEU   A 1 126 ? 158.523 134.379 136.061 1.00 72.79  ? 152 LEU   A C   1 
ATOM   1000 O O   . LEU   A 1 126 ? 159.737 134.207 136.211 1.00 79.03  ? 152 LEU   A O   1 
ATOM   1001 C CB  . LEU   A 1 126 ? 158.032 134.335 133.626 1.00 63.26  ? 152 LEU   A CB  1 
ATOM   1002 C CG  . LEU   A 1 126 ? 159.114 133.760 132.708 1.00 68.04  ? 152 LEU   A CG  1 
ATOM   1003 C CD1 . LEU   A 1 126 ? 159.289 134.670 131.513 1.00 71.04  ? 152 LEU   A CD1 1 
ATOM   1004 C CD2 . LEU   A 1 126 ? 160.449 133.558 133.413 1.00 73.74  ? 152 LEU   A CD2 1 
ATOM   1005 N N   . ASP   A 1 127 ? 157.821 135.206 136.834 1.00 69.73  ? 153 ASP   A N   1 
ATOM   1006 C CA  . ASP   A 1 127 ? 158.467 136.045 137.842 1.00 71.57  ? 153 ASP   A CA  1 
ATOM   1007 C C   . ASP   A 1 127 ? 157.533 136.147 139.038 1.00 73.94  ? 153 ASP   A C   1 
ATOM   1008 O O   . ASP   A 1 127 ? 156.482 136.787 138.953 1.00 74.57  ? 153 ASP   A O   1 
ATOM   1009 C CB  . ASP   A 1 127 ? 158.791 137.423 137.275 1.00 72.81  ? 153 ASP   A CB  1 
ATOM   1010 C CG  . ASP   A 1 127 ? 159.849 138.150 138.079 1.00 85.86  ? 153 ASP   A CG  1 
ATOM   1011 O OD1 . ASP   A 1 127 ? 159.950 137.902 139.299 1.00 85.79  ? 153 ASP   A OD1 1 
ATOM   1012 O OD2 . ASP   A 1 127 ? 160.580 138.974 137.490 1.00 89.43  ? 153 ASP   A OD2 1 
ATOM   1013 N N   . LYS   A 1 128 ? 157.925 135.522 140.151 1.00 73.25  ? 154 LYS   A N   1 
ATOM   1014 C CA  . LYS   A 1 128 ? 157.100 135.544 141.350 1.00 71.86  ? 154 LYS   A CA  1 
ATOM   1015 C C   . LYS   A 1 128 ? 157.076 136.912 142.020 1.00 75.85  ? 154 LYS   A C   1 
ATOM   1016 O O   . LYS   A 1 128 ? 156.186 137.166 142.837 1.00 78.95  ? 154 LYS   A O   1 
ATOM   1017 C CB  . LYS   A 1 128 ? 157.590 134.492 142.344 1.00 69.56  ? 154 LYS   A CB  1 
ATOM   1018 C CG  . LYS   A 1 128 ? 157.269 133.068 141.931 1.00 65.58  ? 154 LYS   A CG  1 
ATOM   1019 C CD  . LYS   A 1 128 ? 157.575 132.066 143.031 1.00 64.14  ? 154 LYS   A CD  1 
ATOM   1020 C CE  . LYS   A 1 128 ? 159.062 131.929 143.279 1.00 69.03  ? 154 LYS   A CE  1 
ATOM   1021 N NZ  . LYS   A 1 128 ? 159.362 130.811 144.207 1.00 68.70  ? 154 LYS   A NZ  1 
ATOM   1022 N N   . THR   A 1 129 ? 158.021 137.796 141.699 1.00 73.03  ? 155 THR   A N   1 
ATOM   1023 C CA  . THR   A 1 129 ? 158.067 139.106 142.335 1.00 73.28  ? 155 THR   A CA  1 
ATOM   1024 C C   . THR   A 1 129 ? 157.060 140.088 141.752 1.00 76.54  ? 155 THR   A C   1 
ATOM   1025 O O   . THR   A 1 129 ? 156.880 141.168 142.324 1.00 78.44  ? 155 THR   A O   1 
ATOM   1026 C CB  . THR   A 1 129 ? 159.471 139.705 142.222 1.00 74.26  ? 155 THR   A CB  1 
ATOM   1027 O OG1 . THR   A 1 129 ? 159.737 140.062 140.861 1.00 78.00  ? 155 THR   A OG1 1 
ATOM   1028 C CG2 . THR   A 1 129 ? 160.517 138.710 142.693 1.00 72.65  ? 155 THR   A CG2 1 
ATOM   1029 N N   . SER   A 1 130 ? 156.403 139.744 140.642 1.00 77.48  ? 156 SER   A N   1 
ATOM   1030 C CA  . SER   A 1 130 ? 155.368 140.570 140.033 1.00 75.75  ? 156 SER   A CA  1 
ATOM   1031 C C   . SER   A 1 130 ? 153.977 139.989 140.267 1.00 79.78  ? 156 SER   A C   1 
ATOM   1032 O O   . SER   A 1 130 ? 153.060 140.221 139.475 1.00 83.35  ? 156 SER   A O   1 
ATOM   1033 C CB  . SER   A 1 130 ? 155.630 140.731 138.536 1.00 84.50  ? 156 SER   A CB  1 
ATOM   1034 O OG  . SER   A 1 130 ? 155.610 139.477 137.878 1.00 88.50  ? 156 SER   A OG  1 
ATOM   1035 N N   . TRP   A 1 131 ? 153.808 139.233 141.350 1.00 79.89  ? 157 TRP   A N   1 
ATOM   1036 C CA  . TRP   A 1 131 ? 152.519 138.656 141.705 1.00 74.81  ? 157 TRP   A CA  1 
ATOM   1037 C C   . TRP   A 1 131 ? 151.742 139.628 142.579 1.00 72.07  ? 157 TRP   A C   1 
ATOM   1038 O O   . TRP   A 1 131 ? 152.270 140.150 143.566 1.00 75.92  ? 157 TRP   A O   1 
ATOM   1039 C CB  . TRP   A 1 131 ? 152.698 137.329 142.439 1.00 69.35  ? 157 TRP   A CB  1 
ATOM   1040 C CG  . TRP   A 1 131 ? 153.002 136.172 141.549 1.00 67.84  ? 157 TRP   A CG  1 
ATOM   1041 C CD1 . TRP   A 1 131 ? 153.600 136.209 140.325 1.00 71.76  ? 157 TRP   A CD1 1 
ATOM   1042 C CD2 . TRP   A 1 131 ? 152.710 134.798 141.811 1.00 66.06  ? 157 TRP   A CD2 1 
ATOM   1043 N NE1 . TRP   A 1 131 ? 153.705 134.940 139.812 1.00 71.99  ? 157 TRP   A NE1 1 
ATOM   1044 C CE2 . TRP   A 1 131 ? 153.163 134.056 140.706 1.00 66.00  ? 157 TRP   A CE2 1 
ATOM   1045 C CE3 . TRP   A 1 131 ? 152.111 134.122 142.876 1.00 74.01  ? 157 TRP   A CE3 1 
ATOM   1046 C CZ2 . TRP   A 1 131 ? 153.038 132.674 140.636 1.00 67.08  ? 157 TRP   A CZ2 1 
ATOM   1047 C CZ3 . TRP   A 1 131 ? 151.987 132.752 142.804 1.00 72.94  ? 157 TRP   A CZ3 1 
ATOM   1048 C CH2 . TRP   A 1 131 ? 152.447 132.042 141.692 1.00 68.46  ? 157 TRP   A CH2 1 
ATOM   1049 N N   . ASN   A 1 132 ? 150.488 139.864 142.213 1.00 67.65  ? 158 ASN   A N   1 
ATOM   1050 C CA  . ASN   A 1 132 ? 149.588 140.677 143.010 1.00 66.02  ? 158 ASN   A CA  1 
ATOM   1051 C C   . ASN   A 1 132 ? 148.179 140.151 142.800 1.00 76.77  ? 158 ASN   A C   1 
ATOM   1052 O O   . ASN   A 1 132 ? 147.906 139.416 141.848 1.00 80.33  ? 158 ASN   A O   1 
ATOM   1053 C CB  . ASN   A 1 132 ? 149.686 142.160 142.641 1.00 68.94  ? 158 ASN   A CB  1 
ATOM   1054 C CG  . ASN   A 1 132 ? 149.723 142.384 141.146 1.00 84.38  ? 158 ASN   A CG  1 
ATOM   1055 O OD1 . ASN   A 1 132 ? 148.697 142.313 140.471 1.00 90.92  ? 158 ASN   A OD1 1 
ATOM   1056 N ND2 . ASN   A 1 132 ? 150.911 142.658 140.617 1.00 82.01  ? 158 ASN   A ND2 1 
ATOM   1057 N N   . ASN   A 1 133 ? 147.285 140.528 143.715 1.00 76.75  ? 159 ASN   A N   1 
ATOM   1058 C CA  . ASN   A 1 133 ? 145.940 139.966 143.705 1.00 73.51  ? 159 ASN   A CA  1 
ATOM   1059 C C   . ASN   A 1 133 ? 145.183 140.339 142.437 1.00 71.41  ? 159 ASN   A C   1 
ATOM   1060 O O   . ASN   A 1 133 ? 144.460 139.509 141.874 1.00 72.60  ? 159 ASN   A O   1 
ATOM   1061 C CB  . ASN   A 1 133 ? 145.179 140.428 144.944 1.00 72.97  ? 159 ASN   A CB  1 
ATOM   1062 C CG  . ASN   A 1 133 ? 145.823 139.955 146.226 1.00 75.14  ? 159 ASN   A CG  1 
ATOM   1063 O OD1 . ASN   A 1 133 ? 146.280 140.756 147.039 1.00 81.46  ? 159 ASN   A OD1 1 
ATOM   1064 N ND2 . ASN   A 1 133 ? 145.871 138.644 146.411 1.00 75.04  ? 159 ASN   A ND2 1 
ATOM   1065 N N   . HIS   A 1 134 ? 145.337 141.577 141.966 1.00 67.57  ? 160 HIS   A N   1 
ATOM   1066 C CA  . HIS   A 1 134 ? 144.564 142.000 140.803 1.00 71.07  ? 160 HIS   A CA  1 
ATOM   1067 C C   . HIS   A 1 134 ? 145.064 141.350 139.518 1.00 71.97  ? 160 HIS   A C   1 
ATOM   1068 O O   . HIS   A 1 134 ? 144.262 141.080 138.617 1.00 77.47  ? 160 HIS   A O   1 
ATOM   1069 C CB  . HIS   A 1 134 ? 144.561 143.528 140.676 1.00 75.15  ? 160 HIS   A CB  1 
ATOM   1070 C CG  . HIS   A 1 134 ? 145.921 144.153 140.630 1.00 76.60  ? 160 HIS   A CG  1 
ATOM   1071 N ND1 . HIS   A 1 134 ? 146.589 144.555 141.766 1.00 75.07  ? 160 HIS   A ND1 1 
ATOM   1072 C CD2 . HIS   A 1 134 ? 146.722 144.475 139.588 1.00 77.64  ? 160 HIS   A CD2 1 
ATOM   1073 C CE1 . HIS   A 1 134 ? 147.751 145.084 141.427 1.00 74.28  ? 160 HIS   A CE1 1 
ATOM   1074 N NE2 . HIS   A 1 134 ? 147.857 145.047 140.111 1.00 78.66  ? 160 HIS   A NE2 1 
ATOM   1075 N N   . SER   A 1 135 ? 146.363 141.066 139.412 1.00 66.57  ? 161 SER   A N   1 
ATOM   1076 C CA  . SER   A 1 135 ? 146.848 140.324 138.251 1.00 69.64  ? 161 SER   A CA  1 
ATOM   1077 C C   . SER   A 1 135 ? 146.273 138.914 138.233 1.00 67.28  ? 161 SER   A C   1 
ATOM   1078 O O   . SER   A 1 135 ? 145.856 138.412 137.179 1.00 70.01  ? 161 SER   A O   1 
ATOM   1079 C CB  . SER   A 1 135 ? 148.374 140.277 138.253 1.00 70.47  ? 161 SER   A CB  1 
ATOM   1080 O OG  . SER   A 1 135 ? 148.926 141.573 138.108 1.00 75.29  ? 161 SER   A OG  1 
ATOM   1081 N N   . TYR   A 1 136 ? 146.243 138.261 139.395 1.00 67.25  ? 162 TYR   A N   1 
ATOM   1082 C CA  . TYR   A 1 136 ? 145.629 136.944 139.500 1.00 68.47  ? 162 TYR   A CA  1 
ATOM   1083 C C   . TYR   A 1 136 ? 144.149 137.006 139.146 1.00 70.75  ? 162 TYR   A C   1 
ATOM   1084 O O   . TYR   A 1 136 ? 143.619 136.100 138.490 1.00 72.29  ? 162 TYR   A O   1 
ATOM   1085 C CB  . TYR   A 1 136 ? 145.839 136.404 140.914 1.00 69.74  ? 162 TYR   A CB  1 
ATOM   1086 C CG  . TYR   A 1 136 ? 145.294 135.021 141.164 1.00 68.30  ? 162 TYR   A CG  1 
ATOM   1087 C CD1 . TYR   A 1 136 ? 145.795 133.923 140.485 1.00 69.85  ? 162 TYR   A CD1 1 
ATOM   1088 C CD2 . TYR   A 1 136 ? 144.301 134.810 142.106 1.00 66.05  ? 162 TYR   A CD2 1 
ATOM   1089 C CE1 . TYR   A 1 136 ? 145.306 132.657 140.721 1.00 72.24  ? 162 TYR   A CE1 1 
ATOM   1090 C CE2 . TYR   A 1 136 ? 143.808 133.549 142.351 1.00 66.30  ? 162 TYR   A CE2 1 
ATOM   1091 C CZ  . TYR   A 1 136 ? 144.312 132.476 141.655 1.00 69.71  ? 162 TYR   A CZ  1 
ATOM   1092 O OH  . TYR   A 1 136 ? 143.822 131.214 141.895 1.00 71.81  ? 162 TYR   A OH  1 
ATOM   1093 N N   . LEU   A 1 137 ? 143.468 138.075 139.564 1.00 67.97  ? 163 LEU   A N   1 
ATOM   1094 C CA  . LEU   A 1 137 ? 142.058 138.232 139.225 1.00 64.48  ? 163 LEU   A CA  1 
ATOM   1095 C C   . LEU   A 1 137 ? 141.867 138.383 137.723 1.00 65.41  ? 163 LEU   A C   1 
ATOM   1096 O O   . LEU   A 1 137 ? 140.940 137.802 137.148 1.00 69.95  ? 163 LEU   A O   1 
ATOM   1097 C CB  . LEU   A 1 137 ? 141.478 139.440 139.964 1.00 64.33  ? 163 LEU   A CB  1 
ATOM   1098 C CG  . LEU   A 1 137 ? 140.001 139.772 139.737 1.00 67.80  ? 163 LEU   A CG  1 
ATOM   1099 C CD1 . LEU   A 1 137 ? 139.115 138.619 140.162 1.00 69.83  ? 163 LEU   A CD1 1 
ATOM   1100 C CD2 . LEU   A 1 137 ? 139.632 141.032 140.488 1.00 69.13  ? 163 LEU   A CD2 1 
ATOM   1101 N N   . TYR   A 1 138 ? 142.725 139.171 137.072 1.00 65.92  ? 164 TYR   A N   1 
ATOM   1102 C CA  . TYR   A 1 138 ? 142.626 139.325 135.623 1.00 61.92  ? 164 TYR   A CA  1 
ATOM   1103 C C   . TYR   A 1 138 ? 142.858 137.994 134.926 1.00 58.90  ? 164 TYR   A C   1 
ATOM   1104 O O   . TYR   A 1 138 ? 142.165 137.659 133.956 1.00 64.86  ? 164 TYR   A O   1 
ATOM   1105 C CB  . TYR   A 1 138 ? 143.634 140.359 135.118 1.00 60.49  ? 164 TYR   A CB  1 
ATOM   1106 C CG  . TYR   A 1 138 ? 143.556 141.733 135.755 1.00 65.38  ? 164 TYR   A CG  1 
ATOM   1107 C CD1 . TYR   A 1 138 ? 142.383 142.205 136.331 1.00 70.22  ? 164 TYR   A CD1 1 
ATOM   1108 C CD2 . TYR   A 1 138 ? 144.666 142.561 135.774 1.00 63.96  ? 164 TYR   A CD2 1 
ATOM   1109 C CE1 . TYR   A 1 138 ? 142.327 143.457 136.907 1.00 74.09  ? 164 TYR   A CE1 1 
ATOM   1110 C CE2 . TYR   A 1 138 ? 144.617 143.811 136.346 1.00 67.32  ? 164 TYR   A CE2 1 
ATOM   1111 C CZ  . TYR   A 1 138 ? 143.448 144.255 136.911 1.00 76.68  ? 164 TYR   A CZ  1 
ATOM   1112 O OH  . TYR   A 1 138 ? 143.405 145.504 137.480 1.00 83.31  ? 164 TYR   A OH  1 
ATOM   1113 N N   . GLY   A 1 139 ? 143.832 137.221 135.409 1.00 55.87  ? 165 GLY   A N   1 
ATOM   1114 C CA  . GLY   A 1 139 ? 144.065 135.903 134.842 1.00 56.60  ? 165 GLY   A CA  1 
ATOM   1115 C C   . GLY   A 1 139 ? 142.863 134.990 134.984 1.00 60.10  ? 165 GLY   A C   1 
ATOM   1116 O O   . GLY   A 1 139 ? 142.484 134.292 134.039 1.00 65.08  ? 165 GLY   A O   1 
ATOM   1117 N N   . LEU   A 1 140 ? 142.243 134.986 136.166 1.00 61.85  ? 166 LEU   A N   1 
ATOM   1118 C CA  . LEU   A 1 140 ? 141.068 134.144 136.375 1.00 61.85  ? 166 LEU   A CA  1 
ATOM   1119 C C   . LEU   A 1 140 ? 139.909 134.583 135.490 1.00 60.87  ? 166 LEU   A C   1 
ATOM   1120 O O   . LEU   A 1 140 ? 139.190 133.743 134.938 1.00 60.74  ? 166 LEU   A O   1 
ATOM   1121 C CB  . LEU   A 1 140 ? 140.650 134.170 137.845 1.00 62.57  ? 166 LEU   A CB  1 
ATOM   1122 C CG  . LEU   A 1 140 ? 141.563 133.511 138.884 1.00 67.96  ? 166 LEU   A CG  1 
ATOM   1123 C CD1 . LEU   A 1 140 ? 140.960 133.693 140.269 1.00 69.76  ? 166 LEU   A CD1 1 
ATOM   1124 C CD2 . LEU   A 1 140 ? 141.797 132.036 138.590 1.00 68.59  ? 166 LEU   A CD2 1 
ATOM   1125 N N   . LEU   A 1 141 ? 139.699 135.894 135.353 1.00 61.84  ? 167 LEU   A N   1 
ATOM   1126 C CA  . LEU   A 1 141 ? 138.627 136.380 134.490 1.00 60.37  ? 167 LEU   A CA  1 
ATOM   1127 C C   . LEU   A 1 141 ? 138.867 135.983 133.039 1.00 58.77  ? 167 LEU   A C   1 
ATOM   1128 O O   . LEU   A 1 141 ? 137.937 135.562 132.340 1.00 66.72  ? 167 LEU   A O   1 
ATOM   1129 C CB  . LEU   A 1 141 ? 138.493 137.897 134.613 1.00 60.77  ? 167 LEU   A CB  1 
ATOM   1130 C CG  . LEU   A 1 141 ? 137.988 138.447 135.949 1.00 59.98  ? 167 LEU   A CG  1 
ATOM   1131 C CD1 . LEU   A 1 141 ? 138.137 139.956 135.984 1.00 66.09  ? 167 LEU   A CD1 1 
ATOM   1132 C CD2 . LEU   A 1 141 ? 136.546 138.057 136.195 1.00 62.65  ? 167 LEU   A CD2 1 
ATOM   1133 N N   . ALA   A 1 142 ? 140.110 136.106 132.570 1.00 54.03  ? 168 ALA   A N   1 
ATOM   1134 C CA  . ALA   A 1 142 ? 140.424 135.690 131.208 1.00 53.62  ? 168 ALA   A CA  1 
ATOM   1135 C C   . ALA   A 1 142 ? 140.192 134.197 131.025 1.00 55.13  ? 168 ALA   A C   1 
ATOM   1136 O O   . ALA   A 1 142 ? 139.687 133.763 129.983 1.00 63.24  ? 168 ALA   A O   1 
ATOM   1137 C CB  . ALA   A 1 142 ? 141.868 136.056 130.871 1.00 53.47  ? 168 ALA   A CB  1 
ATOM   1138 N N   . PHE   A 1 143 ? 140.563 133.392 132.024 1.00 56.86  ? 169 PHE   A N   1 
ATOM   1139 C CA  . PHE   A 1 143 ? 140.324 131.954 131.941 1.00 58.57  ? 169 PHE   A CA  1 
ATOM   1140 C C   . PHE   A 1 143 ? 138.834 131.644 131.876 1.00 58.71  ? 169 PHE   A C   1 
ATOM   1141 O O   . PHE   A 1 143 ? 138.407 130.777 131.104 1.00 63.07  ? 169 PHE   A O   1 
ATOM   1142 C CB  . PHE   A 1 143 ? 140.958 131.248 133.138 1.00 59.37  ? 169 PHE   A CB  1 
ATOM   1143 C CG  . PHE   A 1 143 ? 140.735 129.766 133.154 1.00 54.69  ? 169 PHE   A CG  1 
ATOM   1144 C CD1 . PHE   A 1 143 ? 141.400 128.942 132.268 1.00 59.81  ? 169 PHE   A CD1 1 
ATOM   1145 C CD2 . PHE   A 1 143 ? 139.866 129.195 134.062 1.00 57.60  ? 169 PHE   A CD2 1 
ATOM   1146 C CE1 . PHE   A 1 143 ? 141.197 127.579 132.282 1.00 63.71  ? 169 PHE   A CE1 1 
ATOM   1147 C CE2 . PHE   A 1 143 ? 139.659 127.835 134.082 1.00 62.77  ? 169 PHE   A CE2 1 
ATOM   1148 C CZ  . PHE   A 1 143 ? 140.325 127.025 133.191 1.00 64.65  ? 169 PHE   A CZ  1 
ATOM   1149 N N   . GLN   A 1 144 ? 138.031 132.331 132.689 1.00 62.33  ? 170 GLN   A N   1 
ATOM   1150 C CA  . GLN   A 1 144 ? 136.589 132.103 132.678 1.00 63.09  ? 170 GLN   A CA  1 
ATOM   1151 C C   . GLN   A 1 144 ? 135.986 132.467 131.330 1.00 65.25  ? 170 GLN   A C   1 
ATOM   1152 O O   . GLN   A 1 144 ? 135.227 131.687 130.744 1.00 68.81  ? 170 GLN   A O   1 
ATOM   1153 C CB  . GLN   A 1 144 ? 135.922 132.917 133.785 1.00 59.92  ? 170 GLN   A CB  1 
ATOM   1154 C CG  . GLN   A 1 144 ? 136.217 132.447 135.183 1.00 62.48  ? 170 GLN   A CG  1 
ATOM   1155 C CD  . GLN   A 1 144 ? 135.690 133.406 136.224 1.00 65.47  ? 170 GLN   A CD  1 
ATOM   1156 O OE1 . GLN   A 1 144 ? 134.675 134.067 136.015 1.00 65.22  ? 170 GLN   A OE1 1 
ATOM   1157 N NE2 . GLN   A 1 144 ? 136.383 133.497 137.351 1.00 68.96  ? 170 GLN   A NE2 1 
ATOM   1158 N N   . LEU   A 1 145 ? 136.320 133.652 130.815 1.00 64.04  ? 171 LEU   A N   1 
ATOM   1159 C CA  . LEU   A 1 145 ? 135.656 134.152 129.616 1.00 59.30  ? 171 LEU   A CA  1 
ATOM   1160 C C   . LEU   A 1 145 ? 136.012 133.355 128.366 1.00 61.19  ? 171 LEU   A C   1 
ATOM   1161 O O   . LEU   A 1 145 ? 135.330 133.500 127.346 1.00 64.02  ? 171 LEU   A O   1 
ATOM   1162 C CB  . LEU   A 1 145 ? 135.986 135.632 129.410 1.00 60.08  ? 171 LEU   A CB  1 
ATOM   1163 C CG  . LEU   A 1 145 ? 135.006 136.636 130.032 1.00 60.48  ? 171 LEU   A CG  1 
ATOM   1164 C CD1 . LEU   A 1 145 ? 134.778 136.389 131.515 1.00 65.22  ? 171 LEU   A CD1 1 
ATOM   1165 C CD2 . LEU   A 1 145 ? 135.501 138.049 129.818 1.00 59.26  ? 171 LEU   A CD2 1 
ATOM   1166 N N   . THR   A 1 146 ? 137.057 132.525 128.412 1.00 58.48  ? 172 THR   A N   1 
ATOM   1167 C CA  . THR   A 1 146 ? 137.385 131.696 127.257 1.00 60.91  ? 172 THR   A CA  1 
ATOM   1168 C C   . THR   A 1 146 ? 136.271 130.709 126.940 1.00 65.70  ? 172 THR   A C   1 
ATOM   1169 O O   . THR   A 1 146 ? 136.083 130.340 125.775 1.00 72.98  ? 172 THR   A O   1 
ATOM   1170 C CB  . THR   A 1 146 ? 138.692 130.943 127.500 1.00 68.55  ? 172 THR   A CB  1 
ATOM   1171 O OG1 . THR   A 1 146 ? 139.741 131.874 127.788 1.00 69.47  ? 172 THR   A OG1 1 
ATOM   1172 C CG2 . THR   A 1 146 ? 139.070 130.118 126.276 1.00 71.31  ? 172 THR   A CG2 1 
ATOM   1173 N N   . PHE   A 1 147 ? 135.524 130.273 127.956 1.00 70.89  ? 173 PHE   A N   1 
ATOM   1174 C CA  . PHE   A 1 147 ? 134.423 129.336 127.777 1.00 70.51  ? 173 PHE   A CA  1 
ATOM   1175 C C   . PHE   A 1 147 ? 133.069 130.017 127.633 1.00 70.92  ? 173 PHE   A C   1 
ATOM   1176 O O   . PHE   A 1 147 ? 132.150 129.415 127.070 1.00 72.18  ? 173 PHE   A O   1 
ATOM   1177 C CB  . PHE   A 1 147 ? 134.359 128.367 128.962 1.00 67.61  ? 173 PHE   A CB  1 
ATOM   1178 C CG  . PHE   A 1 147 ? 135.631 127.605 129.197 1.00 69.90  ? 173 PHE   A CG  1 
ATOM   1179 C CD1 . PHE   A 1 147 ? 135.855 126.395 128.567 1.00 74.23  ? 173 PHE   A CD1 1 
ATOM   1180 C CD2 . PHE   A 1 147 ? 136.598 128.093 130.057 1.00 73.38  ? 173 PHE   A CD2 1 
ATOM   1181 C CE1 . PHE   A 1 147 ? 137.021 125.689 128.785 1.00 82.63  ? 173 PHE   A CE1 1 
ATOM   1182 C CE2 . PHE   A 1 147 ? 137.766 127.392 130.278 1.00 77.54  ? 173 PHE   A CE2 1 
ATOM   1183 C CZ  . PHE   A 1 147 ? 137.977 126.188 129.641 1.00 81.47  ? 173 PHE   A CZ  1 
ATOM   1184 N N   . MET   A 1 148 ? 132.925 131.242 128.126 1.00 71.68  ? 174 MET   A N   1 
ATOM   1185 C CA  . MET   A 1 148 ? 131.630 131.905 128.131 1.00 69.89  ? 174 MET   A CA  1 
ATOM   1186 C C   . MET   A 1 148 ? 131.276 132.427 126.744 1.00 70.64  ? 174 MET   A C   1 
ATOM   1187 O O   . MET   A 1 148 ? 132.142 132.835 125.966 1.00 72.63  ? 174 MET   A O   1 
ATOM   1188 C CB  . MET   A 1 148 ? 131.634 133.054 129.136 1.00 73.56  ? 174 MET   A CB  1 
ATOM   1189 C CG  . MET   A 1 148 ? 131.918 132.615 130.561 1.00 72.81  ? 174 MET   A CG  1 
ATOM   1190 S SD  . MET   A 1 148 ? 131.882 133.970 131.739 1.00 78.24  ? 174 MET   A SD  1 
ATOM   1191 C CE  . MET   A 1 148 ? 132.039 133.054 133.264 1.00 68.09  ? 174 MET   A CE  1 
ATOM   1192 N N   . ASP   A 1 149 ? 129.975 132.414 126.442 1.00 73.58  ? 175 ASP   A N   1 
ATOM   1193 C CA  . ASP   A 1 149 ? 129.462 132.858 125.145 1.00 72.76  ? 175 ASP   A CA  1 
ATOM   1194 C C   . ASP   A 1 149 ? 129.135 134.346 125.235 1.00 66.78  ? 175 ASP   A C   1 
ATOM   1195 O O   . ASP   A 1 149 ? 127.977 134.762 125.298 1.00 66.53  ? 175 ASP   A O   1 
ATOM   1196 C CB  . ASP   A 1 149 ? 128.241 132.037 124.747 1.00 76.09  ? 175 ASP   A CB  1 
ATOM   1197 C CG  . ASP   A 1 149 ? 128.443 130.549 124.958 1.00 80.54  ? 175 ASP   A CG  1 
ATOM   1198 O OD1 . ASP   A 1 149 ? 128.630 130.136 126.121 1.00 74.00  ? 175 ASP   A OD1 1 
ATOM   1199 O OD2 . ASP   A 1 149 ? 128.408 129.793 123.965 1.00 81.05  ? 175 ASP   A OD2 1 
ATOM   1200 N N   . ALA   A 1 150 ? 130.189 135.160 125.232 1.00 66.03  ? 176 ALA   A N   1 
ATOM   1201 C CA  . ALA   A 1 150 ? 130.068 136.606 125.366 1.00 63.69  ? 176 ALA   A CA  1 
ATOM   1202 C C   . ALA   A 1 150 ? 130.077 137.341 124.031 1.00 63.79  ? 176 ALA   A C   1 
ATOM   1203 O O   . ALA   A 1 150 ? 130.033 138.574 124.026 1.00 63.70  ? 176 ALA   A O   1 
ATOM   1204 C CB  . ALA   A 1 150 ? 131.197 137.144 126.251 1.00 63.01  ? 176 ALA   A CB  1 
ATOM   1205 N N   . ASN   A 1 151 ? 130.132 136.625 122.907 1.00 63.49  ? 177 ASN   A N   1 
ATOM   1206 C CA  . ASN   A 1 151 ? 130.154 137.226 121.579 1.00 58.32  ? 177 ASN   A CA  1 
ATOM   1207 C C   . ASN   A 1 151 ? 128.775 137.261 120.932 1.00 62.62  ? 177 ASN   A C   1 
ATOM   1208 O O   . ASN   A 1 151 ? 128.678 137.352 119.705 1.00 68.66  ? 177 ASN   A O   1 
ATOM   1209 C CB  . ASN   A 1 151 ? 131.144 136.484 120.678 1.00 57.90  ? 177 ASN   A CB  1 
ATOM   1210 C CG  . ASN   A 1 151 ? 130.784 135.027 120.480 1.00 62.81  ? 177 ASN   A CG  1 
ATOM   1211 O OD1 . ASN   A 1 151 ? 130.212 134.392 121.364 1.00 66.86  ? 177 ASN   A OD1 1 
ATOM   1212 N ND2 . ASN   A 1 151 ? 131.124 134.487 119.319 1.00 69.57  ? 177 ASN   A ND2 1 
ATOM   1213 N N   . HIS   A 1 152 ? 127.709 137.195 121.731 1.00 62.52  ? 178 HIS   A N   1 
ATOM   1214 C CA  . HIS   A 1 152 ? 126.352 137.146 121.205 1.00 60.72  ? 178 HIS   A CA  1 
ATOM   1215 C C   . HIS   A 1 152 ? 125.712 138.516 121.038 1.00 58.87  ? 178 HIS   A C   1 
ATOM   1216 O O   . HIS   A 1 152 ? 124.783 138.647 120.234 1.00 68.90  ? 178 HIS   A O   1 
ATOM   1217 C CB  . HIS   A 1 152 ? 125.468 136.287 122.114 1.00 61.16  ? 178 HIS   A CB  1 
ATOM   1218 C CG  . HIS   A 1 152 ? 125.719 134.816 121.986 1.00 61.48  ? 178 HIS   A CG  1 
ATOM   1219 N ND1 . HIS   A 1 152 ? 124.825 133.866 122.429 1.00 57.39  ? 178 HIS   A ND1 1 
ATOM   1220 C CD2 . HIS   A 1 152 ? 126.763 134.132 121.463 1.00 66.48  ? 178 HIS   A CD2 1 
ATOM   1221 C CE1 . HIS   A 1 152 ? 125.308 132.662 122.184 1.00 57.07  ? 178 HIS   A CE1 1 
ATOM   1222 N NE2 . HIS   A 1 152 ? 126.483 132.796 121.598 1.00 59.83  ? 178 HIS   A NE2 1 
ATOM   1223 N N   . TYR   A 1 153 ? 126.174 139.531 121.766 1.00 54.65  ? 179 TYR   A N   1 
ATOM   1224 C CA  . TYR   A 1 153 ? 125.598 140.871 121.713 1.00 57.37  ? 179 TYR   A CA  1 
ATOM   1225 C C   . TYR   A 1 153 ? 126.702 141.898 121.533 1.00 66.01  ? 179 TYR   A C   1 
ATOM   1226 O O   . TYR   A 1 153 ? 127.718 141.850 122.234 1.00 69.99  ? 179 TYR   A O   1 
ATOM   1227 C CB  . TYR   A 1 153 ? 124.809 141.174 122.980 1.00 59.26  ? 179 TYR   A CB  1 
ATOM   1228 C CG  . TYR   A 1 153 ? 123.997 142.448 122.934 1.00 59.35  ? 179 TYR   A CG  1 
ATOM   1229 C CD1 . TYR   A 1 153 ? 122.817 142.516 122.213 1.00 64.30  ? 179 TYR   A CD1 1 
ATOM   1230 C CD2 . TYR   A 1 153 ? 124.395 143.571 123.639 1.00 61.36  ? 179 TYR   A CD2 1 
ATOM   1231 C CE1 . TYR   A 1 153 ? 122.067 143.671 122.183 1.00 70.04  ? 179 TYR   A CE1 1 
ATOM   1232 C CE2 . TYR   A 1 153 ? 123.650 144.728 123.616 1.00 65.49  ? 179 TYR   A CE2 1 
ATOM   1233 C CZ  . TYR   A 1 153 ? 122.487 144.772 122.889 1.00 71.70  ? 179 TYR   A CZ  1 
ATOM   1234 O OH  . TYR   A 1 153 ? 121.742 145.926 122.864 1.00 79.06  ? 179 TYR   A OH  1 
ATOM   1235 N N   . TRP   A 1 154 ? 126.490 142.827 120.602 1.00 62.76  ? 180 TRP   A N   1 
ATOM   1236 C CA  . TRP   A 1 154 ? 127.428 143.910 120.323 1.00 58.60  ? 180 TRP   A CA  1 
ATOM   1237 C C   . TRP   A 1 154 ? 128.815 143.353 120.001 1.00 52.87  ? 180 TRP   A C   1 
ATOM   1238 O O   . TRP   A 1 154 ? 129.802 143.628 120.683 1.00 63.99  ? 180 TRP   A O   1 
ATOM   1239 C CB  . TRP   A 1 154 ? 127.477 144.885 121.505 1.00 64.08  ? 180 TRP   A CB  1 
ATOM   1240 C CG  . TRP   A 1 154 ? 128.159 146.201 121.236 1.00 70.12  ? 180 TRP   A CG  1 
ATOM   1241 C CD1 . TRP   A 1 154 ? 128.432 146.763 120.020 1.00 75.93  ? 180 TRP   A CD1 1 
ATOM   1242 C CD2 . TRP   A 1 154 ? 128.653 147.118 122.218 1.00 68.22  ? 180 TRP   A CD2 1 
ATOM   1243 N NE1 . TRP   A 1 154 ? 129.062 147.970 120.187 1.00 78.87  ? 180 TRP   A NE1 1 
ATOM   1244 C CE2 . TRP   A 1 154 ? 129.211 148.211 121.527 1.00 73.43  ? 180 TRP   A CE2 1 
ATOM   1245 C CE3 . TRP   A 1 154 ? 128.680 147.119 123.614 1.00 68.89  ? 180 TRP   A CE3 1 
ATOM   1246 C CZ2 . TRP   A 1 154 ? 129.787 149.293 122.186 1.00 75.68  ? 180 TRP   A CZ2 1 
ATOM   1247 C CZ3 . TRP   A 1 154 ? 129.252 148.193 124.265 1.00 76.99  ? 180 TRP   A CZ3 1 
ATOM   1248 C CH2 . TRP   A 1 154 ? 129.798 149.265 123.552 1.00 77.42  ? 180 TRP   A CH2 1 
ATOM   1249 N N   . SER   A 1 155 ? 128.865 142.547 118.943 1.00 44.95  ? 181 SER   A N   1 
ATOM   1250 C CA  . SER   A 1 155 ? 130.082 141.865 118.534 1.00 58.19  ? 181 SER   A CA  1 
ATOM   1251 C C   . SER   A 1 155 ? 130.177 141.853 117.018 1.00 64.30  ? 181 SER   A C   1 
ATOM   1252 O O   . SER   A 1 155 ? 129.179 141.638 116.325 1.00 69.55  ? 181 SER   A O   1 
ATOM   1253 C CB  . SER   A 1 155 ? 130.122 140.429 119.064 1.00 65.51  ? 181 SER   A CB  1 
ATOM   1254 O OG  . SER   A 1 155 ? 129.043 139.670 118.547 1.00 69.45  ? 181 SER   A OG  1 
ATOM   1255 N N   . VAL   A 1 156 ? 131.390 142.082 116.510 1.00 64.04  ? 182 VAL   A N   1 
ATOM   1256 C CA  . VAL   A 1 156 ? 131.620 142.036 115.070 1.00 62.76  ? 182 VAL   A CA  1 
ATOM   1257 C C   . VAL   A 1 156 ? 131.401 140.628 114.539 1.00 67.05  ? 182 VAL   A C   1 
ATOM   1258 O O   . VAL   A 1 156 ? 130.967 140.449 113.393 1.00 73.06  ? 182 VAL   A O   1 
ATOM   1259 C CB  . VAL   A 1 156 ? 133.032 142.553 114.737 1.00 63.18  ? 182 VAL   A CB  1 
ATOM   1260 C CG1 . VAL   A 1 156 ? 133.295 142.456 113.240 1.00 67.25  ? 182 VAL   A CG1 1 
ATOM   1261 C CG2 . VAL   A 1 156 ? 133.201 143.987 115.223 1.00 64.14  ? 182 VAL   A CG2 1 
ATOM   1262 N N   . ASP   A 1 157 ? 131.709 139.609 115.346 1.00 66.18  ? 183 ASP   A N   1 
ATOM   1263 C CA  . ASP   A 1 157 ? 131.479 138.231 114.926 1.00 69.46  ? 183 ASP   A CA  1 
ATOM   1264 C C   . ASP   A 1 157 ? 130.009 137.980 114.617 1.00 73.30  ? 183 ASP   A C   1 
ATOM   1265 O O   . ASP   A 1 157 ? 129.689 137.162 113.747 1.00 81.09  ? 183 ASP   A O   1 
ATOM   1266 C CB  . ASP   A 1 157 ? 131.968 137.269 116.008 1.00 64.07  ? 183 ASP   A CB  1 
ATOM   1267 C CG  . ASP   A 1 157 ? 131.959 135.823 115.556 1.00 73.88  ? 183 ASP   A CG  1 
ATOM   1268 O OD1 . ASP   A 1 157 ? 131.763 135.568 114.349 1.00 78.70  ? 183 ASP   A OD1 1 
ATOM   1269 O OD2 . ASP   A 1 157 ? 132.149 134.935 116.413 1.00 76.94  ? 183 ASP   A OD2 1 
ATOM   1270 N N   . GLY   A 1 158 ? 129.104 138.672 115.309 1.00 64.98  ? 184 GLY   A N   1 
ATOM   1271 C CA  . GLY   A 1 158 ? 127.697 138.564 114.971 1.00 64.80  ? 184 GLY   A CA  1 
ATOM   1272 C C   . GLY   A 1 158 ? 127.402 139.068 113.572 1.00 69.31  ? 184 GLY   A C   1 
ATOM   1273 O O   . GLY   A 1 158 ? 126.677 138.426 112.810 1.00 75.19  ? 184 GLY   A O   1 
ATOM   1274 N N   . LEU   A 1 159 ? 127.968 140.221 113.210 1.00 65.42  ? 185 LEU   A N   1 
ATOM   1275 C CA  . LEU   A 1 159 ? 127.790 140.733 111.857 1.00 59.93  ? 185 LEU   A CA  1 
ATOM   1276 C C   . LEU   A 1 159 ? 128.433 139.812 110.831 1.00 67.27  ? 185 LEU   A C   1 
ATOM   1277 O O   . LEU   A 1 159 ? 127.926 139.679 109.711 1.00 73.26  ? 185 LEU   A O   1 
ATOM   1278 C CB  . LEU   A 1 159 ? 128.370 142.143 111.750 1.00 53.71  ? 185 LEU   A CB  1 
ATOM   1279 C CG  . LEU   A 1 159 ? 127.751 143.193 112.676 1.00 56.61  ? 185 LEU   A CG  1 
ATOM   1280 C CD1 . LEU   A 1 159 ? 128.548 144.480 112.629 1.00 57.62  ? 185 LEU   A CD1 1 
ATOM   1281 C CD2 . LEU   A 1 159 ? 126.302 143.462 112.309 1.00 62.47  ? 185 LEU   A CD2 1 
ATOM   1282 N N   . LEU   A 1 160 ? 129.542 139.168 111.193 1.00 70.92  ? 186 LEU   A N   1 
ATOM   1283 C CA  . LEU   A 1 160 ? 130.175 138.199 110.306 1.00 67.08  ? 186 LEU   A CA  1 
ATOM   1284 C C   . LEU   A 1 160 ? 129.450 136.860 110.276 1.00 73.80  ? 186 LEU   A C   1 
ATOM   1285 O O   . LEU   A 1 160 ? 129.687 136.071 109.355 1.00 78.48  ? 186 LEU   A O   1 
ATOM   1286 C CB  . LEU   A 1 160 ? 131.632 137.970 110.717 1.00 70.60  ? 186 LEU   A CB  1 
ATOM   1287 C CG  . LEU   A 1 160 ? 132.681 138.871 110.060 1.00 80.98  ? 186 LEU   A CG  1 
ATOM   1288 C CD1 . LEU   A 1 160 ? 132.421 140.341 110.357 1.00 81.32  ? 186 LEU   A CD1 1 
ATOM   1289 C CD2 . LEU   A 1 160 ? 134.075 138.471 110.517 1.00 80.81  ? 186 LEU   A CD2 1 
ATOM   1290 N N   . ASN   A 1 161 ? 128.582 136.584 111.250 1.00 78.64  ? 187 ASN   A N   1 
ATOM   1291 C CA  . ASN   A 1 161 ? 127.890 135.298 111.325 1.00 80.02  ? 187 ASN   A CA  1 
ATOM   1292 C C   . ASN   A 1 161 ? 126.538 135.530 111.986 1.00 79.58  ? 187 ASN   A C   1 
ATOM   1293 O O   . ASN   A 1 161 ? 126.472 135.800 113.188 1.00 78.33  ? 187 ASN   A O   1 
ATOM   1294 C CB  . ASN   A 1 161 ? 128.714 134.278 112.104 1.00 75.82  ? 187 ASN   A CB  1 
ATOM   1295 C CG  . ASN   A 1 161 ? 128.098 132.899 112.087 1.00 81.98  ? 187 ASN   A CG  1 
ATOM   1296 O OD1 . ASN   A 1 161 ? 127.209 132.615 111.286 1.00 86.97  ? 187 ASN   A OD1 1 
ATOM   1297 N ND2 . ASN   A 1 161 ? 128.568 132.030 112.973 1.00 85.89  ? 187 ASN   A ND2 1 
ATOM   1298 N N   . ALA   A 1 162 ? 125.464 135.406 111.203 1.00 78.54  ? 188 ALA   A N   1 
ATOM   1299 C CA  . ALA   A 1 162 ? 124.141 135.806 111.664 1.00 79.09  ? 188 ALA   A CA  1 
ATOM   1300 C C   . ALA   A 1 162 ? 123.587 134.900 112.756 1.00 80.61  ? 188 ALA   A C   1 
ATOM   1301 O O   . ALA   A 1 162 ? 122.712 135.334 113.512 1.00 80.65  ? 188 ALA   A O   1 
ATOM   1302 C CB  . ALA   A 1 162 ? 123.167 135.837 110.485 1.00 78.04  ? 188 ALA   A CB  1 
ATOM   1303 N N   . HIS   A 1 163 ? 124.064 133.659 112.859 1.00 81.87  ? 189 HIS   A N   1 
ATOM   1304 C CA  . HIS   A 1 163 ? 123.468 132.722 113.806 1.00 85.05  ? 189 HIS   A CA  1 
ATOM   1305 C C   . HIS   A 1 163 ? 123.750 133.105 115.255 1.00 81.01  ? 189 HIS   A C   1 
ATOM   1306 O O   . HIS   A 1 163 ? 122.953 132.775 116.140 1.00 82.87  ? 189 HIS   A O   1 
ATOM   1307 C CB  . HIS   A 1 163 ? 123.972 131.306 113.526 1.00 88.73  ? 189 HIS   A CB  1 
ATOM   1308 C CG  . HIS   A 1 163 ? 123.442 130.716 112.256 1.00 95.33  ? 189 HIS   A CG  1 
ATOM   1309 N ND1 . HIS   A 1 163 ? 123.719 129.424 111.865 1.00 103.06 ? 189 HIS   A ND1 1 
ATOM   1310 C CD2 . HIS   A 1 163 ? 122.649 131.239 111.291 1.00 97.69  ? 189 HIS   A CD2 1 
ATOM   1311 C CE1 . HIS   A 1 163 ? 123.121 129.177 110.713 1.00 109.44 ? 189 HIS   A CE1 1 
ATOM   1312 N NE2 . HIS   A 1 163 ? 122.465 130.262 110.343 1.00 113.00 ? 189 HIS   A NE2 1 
ATOM   1313 N N   . ARG   A 1 164 ? 124.858 133.795 115.517 1.00 74.98  ? 190 ARG   A N   1 
ATOM   1314 C CA  . ARG   A 1 164 ? 125.277 134.164 116.866 1.00 70.27  ? 190 ARG   A CA  1 
ATOM   1315 C C   . ARG   A 1 164 ? 125.073 135.653 117.130 1.00 74.11  ? 190 ARG   A C   1 
ATOM   1316 O O   . ARG   A 1 164 ? 125.869 136.287 117.826 1.00 79.83  ? 190 ARG   A O   1 
ATOM   1317 C CB  . ARG   A 1 164 ? 126.737 133.781 117.099 1.00 71.12  ? 190 ARG   A CB  1 
ATOM   1318 C CG  . ARG   A 1 164 ? 126.998 132.286 117.095 1.00 79.82  ? 190 ARG   A CG  1 
ATOM   1319 C CD  . ARG   A 1 164 ? 128.430 131.976 117.506 1.00 82.63  ? 190 ARG   A CD  1 
ATOM   1320 N NE  . ARG   A 1 164 ? 128.662 130.546 117.683 1.00 93.03  ? 190 ARG   A NE  1 
ATOM   1321 C CZ  . ARG   A 1 164 ? 128.363 129.853 118.776 1.00 92.55  ? 190 ARG   A CZ  1 
ATOM   1322 N NH1 . ARG   A 1 164 ? 127.781 130.416 119.824 1.00 87.91  ? 190 ARG   A NH1 1 
ATOM   1323 N NH2 . ARG   A 1 164 ? 128.655 128.556 118.819 1.00 91.79  ? 190 ARG   A NH2 1 
ATOM   1324 N N   . ARG   A 1 165 ? 124.000 136.227 116.584 1.00 68.95  ? 191 ARG   A N   1 
ATOM   1325 C CA  . ARG   A 1 165 ? 123.711 137.655 116.703 1.00 68.01  ? 191 ARG   A CA  1 
ATOM   1326 C C   . ARG   A 1 165 ? 122.463 137.831 117.559 1.00 64.16  ? 191 ARG   A C   1 
ATOM   1327 O O   . ARG   A 1 165 ? 121.364 137.437 117.154 1.00 67.19  ? 191 ARG   A O   1 
ATOM   1328 C CB  . ARG   A 1 165 ? 123.529 138.285 115.323 1.00 68.39  ? 191 ARG   A CB  1 
ATOM   1329 C CG  . ARG   A 1 165 ? 123.910 139.768 115.253 1.00 72.29  ? 191 ARG   A CG  1 
ATOM   1330 C CD  . ARG   A 1 165 ? 124.092 140.253 113.819 1.00 72.83  ? 191 ARG   A CD  1 
ATOM   1331 N NE  . ARG   A 1 165 ? 122.829 140.581 113.163 1.00 78.45  ? 191 ARG   A NE  1 
ATOM   1332 C CZ  . ARG   A 1 165 ? 122.300 141.795 113.056 1.00 80.46  ? 191 ARG   A CZ  1 
ATOM   1333 N NH1 . ARG   A 1 165 ? 122.878 142.864 113.584 1.00 76.65  ? 191 ARG   A NH1 1 
ATOM   1334 N NH2 . ARG   A 1 165 ? 121.156 141.945 112.395 1.00 82.05  ? 191 ARG   A NH2 1 
ATOM   1335 N N   . ASN   A 1 166 ? 122.638 138.430 118.737 1.00 56.72  ? 192 ASN   A N   1 
ATOM   1336 C CA  . ASN   A 1 166 ? 121.540 138.759 119.643 1.00 52.30  ? 192 ASN   A CA  1 
ATOM   1337 C C   . ASN   A 1 166 ? 120.763 137.505 120.050 1.00 61.06  ? 192 ASN   A C   1 
ATOM   1338 O O   . ASN   A 1 166 ? 119.540 137.433 119.921 1.00 66.89  ? 192 ASN   A O   1 
ATOM   1339 C CB  . ASN   A 1 166 ? 120.614 139.797 119.000 1.00 52.32  ? 192 ASN   A CB  1 
ATOM   1340 C CG  . ASN   A 1 166 ? 119.725 140.486 120.007 1.00 63.03  ? 192 ASN   A CG  1 
ATOM   1341 O OD1 . ASN   A 1 166 ? 119.525 139.994 121.116 1.00 73.57  ? 192 ASN   A OD1 1 
ATOM   1342 N ND2 . ASN   A 1 166 ? 119.180 141.635 119.626 1.00 68.00  ? 192 ASN   A ND2 1 
ATOM   1343 N N   . ALA   A 1 167 ? 121.495 136.525 120.576 1.00 59.41  ? 193 ALA   A N   1 
ATOM   1344 C CA  . ALA   A 1 167 ? 120.946 135.227 120.949 1.00 58.66  ? 193 ALA   A CA  1 
ATOM   1345 C C   . ALA   A 1 167 ? 121.128 134.982 122.441 1.00 65.15  ? 193 ALA   A C   1 
ATOM   1346 O O   . ALA   A 1 167 ? 121.917 135.644 123.118 1.00 67.15  ? 193 ALA   A O   1 
ATOM   1347 C CB  . ALA   A 1 167 ? 121.606 134.100 120.148 1.00 58.61  ? 193 ALA   A CB  1 
ATOM   1348 N N   . HIS   A 1 168 ? 120.388 133.997 122.945 1.00 62.24  ? 194 HIS   A N   1 
ATOM   1349 C CA  . HIS   A 1 168 ? 120.406 133.677 124.363 1.00 51.63  ? 194 HIS   A CA  1 
ATOM   1350 C C   . HIS   A 1 168 ? 121.731 133.039 124.766 1.00 54.14  ? 194 HIS   A C   1 
ATOM   1351 O O   . HIS   A 1 168 ? 122.478 132.511 123.938 1.00 58.75  ? 194 HIS   A O   1 
ATOM   1352 C CB  . HIS   A 1 168 ? 119.266 132.724 124.716 1.00 48.55  ? 194 HIS   A CB  1 
ATOM   1353 C CG  . HIS   A 1 168 ? 117.912 133.360 124.718 1.00 49.08  ? 194 HIS   A CG  1 
ATOM   1354 N ND1 . HIS   A 1 168 ? 116.790 132.713 124.251 1.00 52.67  ? 194 HIS   A ND1 1 
ATOM   1355 C CD2 . HIS   A 1 168 ? 117.494 134.571 125.153 1.00 53.83  ? 194 HIS   A CD2 1 
ATOM   1356 C CE1 . HIS   A 1 168 ? 115.741 133.502 124.385 1.00 49.25  ? 194 HIS   A CE1 1 
ATOM   1357 N NE2 . HIS   A 1 168 ? 116.141 134.636 124.932 1.00 52.62  ? 194 HIS   A NE2 1 
ATOM   1358 N N   . VAL   A 1 169 ? 122.009 133.096 126.065 1.00 50.98  ? 195 VAL   A N   1 
ATOM   1359 C CA  . VAL   A 1 169 ? 123.198 132.493 126.662 1.00 50.99  ? 195 VAL   A CA  1 
ATOM   1360 C C   . VAL   A 1 169 ? 122.765 131.703 127.894 1.00 53.41  ? 195 VAL   A C   1 
ATOM   1361 O O   . VAL   A 1 169 ? 121.770 132.074 128.533 1.00 60.58  ? 195 VAL   A O   1 
ATOM   1362 C CB  . VAL   A 1 169 ? 124.251 133.555 127.023 1.00 54.53  ? 195 VAL   A CB  1 
ATOM   1363 C CG1 . VAL   A 1 169 ? 124.775 134.231 125.766 1.00 62.63  ? 195 VAL   A CG1 1 
ATOM   1364 C CG2 . VAL   A 1 169 ? 123.691 134.594 127.996 1.00 51.33  ? 195 VAL   A CG2 1 
ATOM   1365 N N   . PRO   A 1 170 ? 123.450 130.624 128.271 1.00 46.98  ? 196 PRO   A N   1 
ATOM   1366 C CA  . PRO   A 1 170 ? 123.044 129.886 129.471 1.00 47.66  ? 196 PRO   A CA  1 
ATOM   1367 C C   . PRO   A 1 170 ? 123.269 130.696 130.738 1.00 53.58  ? 196 PRO   A C   1 
ATOM   1368 O O   . PRO   A 1 170 ? 124.025 131.668 130.769 1.00 60.13  ? 196 PRO   A O   1 
ATOM   1369 C CB  . PRO   A 1 170 ? 123.921 128.632 129.443 1.00 54.29  ? 196 PRO   A CB  1 
ATOM   1370 C CG  . PRO   A 1 170 ? 125.060 128.963 128.580 1.00 58.59  ? 196 PRO   A CG  1 
ATOM   1371 C CD  . PRO   A 1 170 ? 124.590 129.978 127.595 1.00 56.41  ? 196 PRO   A CD  1 
ATOM   1372 N N   . LEU   A 1 171 ? 122.582 130.273 131.802 1.00 54.44  ? 197 LEU   A N   1 
ATOM   1373 C CA  . LEU   A 1 171 ? 122.586 131.043 133.041 1.00 50.72  ? 197 LEU   A CA  1 
ATOM   1374 C C   . LEU   A 1 171 ? 123.928 130.985 133.760 1.00 60.16  ? 197 LEU   A C   1 
ATOM   1375 O O   . LEU   A 1 171 ? 124.256 131.907 134.515 1.00 64.78  ? 197 LEU   A O   1 
ATOM   1376 C CB  . LEU   A 1 171 ? 121.475 130.543 133.965 1.00 51.42  ? 197 LEU   A CB  1 
ATOM   1377 C CG  . LEU   A 1 171 ? 121.363 131.164 135.361 1.00 56.53  ? 197 LEU   A CG  1 
ATOM   1378 C CD1 . LEU   A 1 171 ? 121.216 132.671 135.276 1.00 59.08  ? 197 LEU   A CD1 1 
ATOM   1379 C CD2 . LEU   A 1 171 ? 120.193 130.566 136.111 1.00 60.22  ? 197 LEU   A CD2 1 
ATOM   1380 N N   . TRP   A 1 172 ? 124.716 129.927 133.556 1.00 61.53  ? 198 TRP   A N   1 
ATOM   1381 C CA  . TRP   A 1 172 ? 125.930 129.781 134.352 1.00 55.20  ? 198 TRP   A CA  1 
ATOM   1382 C C   . TRP   A 1 172 ? 127.005 130.795 133.977 1.00 58.82  ? 198 TRP   A C   1 
ATOM   1383 O O   . TRP   A 1 172 ? 127.927 131.018 134.774 1.00 65.77  ? 198 TRP   A O   1 
ATOM   1384 C CB  . TRP   A 1 172 ? 126.478 128.356 134.245 1.00 53.68  ? 198 TRP   A CB  1 
ATOM   1385 C CG  . TRP   A 1 172 ? 127.023 127.958 132.909 1.00 51.36  ? 198 TRP   A CG  1 
ATOM   1386 C CD1 . TRP   A 1 172 ? 126.360 127.299 131.919 1.00 57.50  ? 198 TRP   A CD1 1 
ATOM   1387 C CD2 . TRP   A 1 172 ? 128.358 128.157 132.433 1.00 53.23  ? 198 TRP   A CD2 1 
ATOM   1388 N NE1 . TRP   A 1 172 ? 127.194 127.086 130.850 1.00 58.40  ? 198 TRP   A NE1 1 
ATOM   1389 C CE2 . TRP   A 1 172 ? 128.427 127.604 131.141 1.00 51.89  ? 198 TRP   A CE2 1 
ATOM   1390 C CE3 . TRP   A 1 172 ? 129.501 128.754 132.972 1.00 59.11  ? 198 TRP   A CE3 1 
ATOM   1391 C CZ2 . TRP   A 1 172 ? 129.589 127.634 130.379 1.00 54.03  ? 198 TRP   A CZ2 1 
ATOM   1392 C CZ3 . TRP   A 1 172 ? 130.653 128.784 132.213 1.00 61.21  ? 198 TRP   A CZ3 1 
ATOM   1393 C CH2 . TRP   A 1 172 ? 130.689 128.227 130.931 1.00 60.84  ? 198 TRP   A CH2 1 
ATOM   1394 N N   . ASN   A 1 173 ? 126.901 131.420 132.799 1.00 56.69  ? 199 ASN   A N   1 
ATOM   1395 C CA  . ASN   A 1 173 ? 127.833 132.483 132.432 1.00 57.36  ? 199 ASN   A CA  1 
ATOM   1396 C C   . ASN   A 1 173 ? 127.814 133.602 133.464 1.00 58.05  ? 199 ASN   A C   1 
ATOM   1397 O O   . ASN   A 1 173 ? 128.866 134.070 133.913 1.00 64.87  ? 199 ASN   A O   1 
ATOM   1398 C CB  . ASN   A 1 173 ? 127.488 133.046 131.052 1.00 58.69  ? 199 ASN   A CB  1 
ATOM   1399 C CG  . ASN   A 1 173 ? 127.441 131.986 129.976 1.00 68.00  ? 199 ASN   A CG  1 
ATOM   1400 O OD1 . ASN   A 1 173 ? 126.377 131.681 129.445 1.00 72.33  ? 199 ASN   A OD1 1 
ATOM   1401 N ND2 . ASN   A 1 173 ? 128.595 131.440 129.628 1.00 72.53  ? 199 ASN   A ND2 1 
ATOM   1402 N N   . TYR   A 1 174 ? 126.618 134.044 133.852 1.00 49.48  ? 200 TYR   A N   1 
ATOM   1403 C CA  . TYR   A 1 174 ? 126.511 135.080 134.871 1.00 52.36  ? 200 TYR   A CA  1 
ATOM   1404 C C   . TYR   A 1 174 ? 126.839 134.528 136.252 1.00 58.73  ? 200 TYR   A C   1 
ATOM   1405 O O   . TYR   A 1 174 ? 127.416 135.236 137.091 1.00 65.63  ? 200 TYR   A O   1 
ATOM   1406 C CB  . TYR   A 1 174 ? 125.105 135.678 134.859 1.00 53.26  ? 200 TYR   A CB  1 
ATOM   1407 C CG  . TYR   A 1 174 ? 124.729 136.355 133.560 1.00 57.60  ? 200 TYR   A CG  1 
ATOM   1408 C CD1 . TYR   A 1 174 ? 124.221 135.628 132.494 1.00 60.24  ? 200 TYR   A CD1 1 
ATOM   1409 C CD2 . TYR   A 1 174 ? 124.870 137.722 133.404 1.00 54.62  ? 200 TYR   A CD2 1 
ATOM   1410 C CE1 . TYR   A 1 174 ? 123.878 136.242 131.311 1.00 55.25  ? 200 TYR   A CE1 1 
ATOM   1411 C CE2 . TYR   A 1 174 ? 124.526 138.343 132.226 1.00 54.56  ? 200 TYR   A CE2 1 
ATOM   1412 C CZ  . TYR   A 1 174 ? 124.030 137.599 131.185 1.00 55.33  ? 200 TYR   A CZ  1 
ATOM   1413 O OH  . TYR   A 1 174 ? 123.688 138.218 130.006 1.00 64.40  ? 200 TYR   A OH  1 
ATOM   1414 N N   . ALA   A 1 175 ? 126.466 133.271 136.508 1.00 54.69  ? 201 ALA   A N   1 
ATOM   1415 C CA  . ALA   A 1 175 ? 126.640 132.696 137.837 1.00 53.05  ? 201 ALA   A CA  1 
ATOM   1416 C C   . ALA   A 1 175 ? 128.109 132.606 138.218 1.00 57.35  ? 201 ALA   A C   1 
ATOM   1417 O O   . ALA   A 1 175 ? 128.476 132.904 139.360 1.00 61.85  ? 201 ALA   A O   1 
ATOM   1418 C CB  . ALA   A 1 175 ? 125.992 131.316 137.902 1.00 51.66  ? 201 ALA   A CB  1 
ATOM   1419 N N   . VAL   A 1 176 ? 128.966 132.191 137.283 1.00 56.04  ? 202 VAL   A N   1 
ATOM   1420 C CA  . VAL   A 1 176 ? 130.382 132.039 137.609 1.00 51.51  ? 202 VAL   A CA  1 
ATOM   1421 C C   . VAL   A 1 176 ? 131.004 133.390 137.951 1.00 57.86  ? 202 VAL   A C   1 
ATOM   1422 O O   . VAL   A 1 176 ? 131.762 133.509 138.921 1.00 67.22  ? 202 VAL   A O   1 
ATOM   1423 C CB  . VAL   A 1 176 ? 131.123 131.342 136.453 1.00 52.05  ? 202 VAL   A CB  1 
ATOM   1424 C CG1 . VAL   A 1 176 ? 132.623 131.400 136.661 1.00 56.85  ? 202 VAL   A CG1 1 
ATOM   1425 C CG2 . VAL   A 1 176 ? 130.678 129.901 136.331 1.00 56.66  ? 202 VAL   A CG2 1 
ATOM   1426 N N   . LEU   A 1 177 ? 130.695 134.428 137.171 1.00 57.92  ? 203 LEU   A N   1 
ATOM   1427 C CA  . LEU   A 1 177 ? 131.247 135.752 137.450 1.00 61.34  ? 203 LEU   A CA  1 
ATOM   1428 C C   . LEU   A 1 177 ? 130.732 136.304 138.775 1.00 60.73  ? 203 LEU   A C   1 
ATOM   1429 O O   . LEU   A 1 177 ? 131.502 136.887 139.555 1.00 66.33  ? 203 LEU   A O   1 
ATOM   1430 C CB  . LEU   A 1 177 ? 130.917 136.710 136.306 1.00 61.53  ? 203 LEU   A CB  1 
ATOM   1431 C CG  . LEU   A 1 177 ? 131.570 136.400 134.957 1.00 62.58  ? 203 LEU   A CG  1 
ATOM   1432 C CD1 . LEU   A 1 177 ? 130.852 137.114 133.828 1.00 61.89  ? 203 LEU   A CD1 1 
ATOM   1433 C CD2 . LEU   A 1 177 ? 133.037 136.790 134.968 1.00 62.83  ? 203 LEU   A CD2 1 
ATOM   1434 N N   . ARG   A 1 178 ? 129.432 136.144 139.044 1.00 56.90  ? 204 ARG   A N   1 
ATOM   1435 C CA  . ARG   A 1 178 ? 128.888 136.604 140.317 1.00 56.30  ? 204 ARG   A CA  1 
ATOM   1436 C C   . ARG   A 1 178 ? 129.545 135.881 141.484 1.00 65.26  ? 204 ARG   A C   1 
ATOM   1437 O O   . ARG   A 1 178 ? 129.892 136.503 142.496 1.00 72.65  ? 204 ARG   A O   1 
ATOM   1438 C CB  . ARG   A 1 178 ? 127.376 136.399 140.345 1.00 59.67  ? 204 ARG   A CB  1 
ATOM   1439 C CG  . ARG   A 1 178 ? 126.604 137.310 139.408 1.00 59.59  ? 204 ARG   A CG  1 
ATOM   1440 C CD  . ARG   A 1 178 ? 125.137 136.926 139.362 1.00 59.68  ? 204 ARG   A CD  1 
ATOM   1441 N NE  . ARG   A 1 178 ? 124.393 137.694 138.373 1.00 56.00  ? 204 ARG   A NE  1 
ATOM   1442 C CZ  . ARG   A 1 178 ? 123.107 137.525 138.094 1.00 57.66  ? 204 ARG   A CZ  1 
ATOM   1443 N NH1 . ARG   A 1 178 ? 122.374 136.614 138.713 1.00 61.26  ? 204 ARG   A NH1 1 
ATOM   1444 N NH2 . ARG   A 1 178 ? 122.540 138.291 137.168 1.00 62.34  ? 204 ARG   A NH2 1 
ATOM   1445 N N   . GLY   A 1 179 ? 129.728 134.565 141.357 1.00 63.60  ? 205 GLY   A N   1 
ATOM   1446 C CA  . GLY   A 1 179 ? 130.413 133.818 142.396 1.00 61.17  ? 205 GLY   A CA  1 
ATOM   1447 C C   . GLY   A 1 179 ? 131.843 134.275 142.593 1.00 59.98  ? 205 GLY   A C   1 
ATOM   1448 O O   . GLY   A 1 179 ? 132.328 134.342 143.722 1.00 68.04  ? 205 GLY   A O   1 
ATOM   1449 N N   . GLN   A 1 180 ? 132.538 134.593 141.500 1.00 59.40  ? 206 GLN   A N   1 
ATOM   1450 C CA  . GLN   A 1 180 ? 133.914 135.066 141.611 1.00 62.34  ? 206 GLN   A CA  1 
ATOM   1451 C C   . GLN   A 1 180 ? 133.982 136.380 142.379 1.00 63.25  ? 206 GLN   A C   1 
ATOM   1452 O O   . GLN   A 1 180 ? 134.812 136.545 143.283 1.00 69.31  ? 206 GLN   A O   1 
ATOM   1453 C CB  . GLN   A 1 180 ? 134.526 135.218 140.216 1.00 62.89  ? 206 GLN   A CB  1 
ATOM   1454 C CG  . GLN   A 1 180 ? 135.924 135.831 140.181 1.00 67.91  ? 206 GLN   A CG  1 
ATOM   1455 C CD  . GLN   A 1 180 ? 136.904 135.112 141.081 1.00 70.46  ? 206 GLN   A CD  1 
ATOM   1456 O OE1 . GLN   A 1 180 ? 136.818 133.899 141.265 1.00 69.74  ? 206 GLN   A OE1 1 
ATOM   1457 N NE2 . GLN   A 1 180 ? 137.839 135.857 141.654 1.00 71.30  ? 206 GLN   A NE2 1 
ATOM   1458 N N   . ILE   A 1 181 ? 133.110 137.331 142.034 1.00 62.61  ? 207 ILE   A N   1 
ATOM   1459 C CA  . ILE   A 1 181 ? 133.128 138.623 142.720 1.00 63.79  ? 207 ILE   A CA  1 
ATOM   1460 C C   . ILE   A 1 181 ? 132.752 138.452 144.188 1.00 65.45  ? 207 ILE   A C   1 
ATOM   1461 O O   . ILE   A 1 181 ? 133.357 139.070 145.081 1.00 70.51  ? 207 ILE   A O   1 
ATOM   1462 C CB  . ILE   A 1 181 ? 132.195 139.622 142.009 1.00 63.62  ? 207 ILE   A CB  1 
ATOM   1463 C CG1 . ILE   A 1 181 ? 132.649 139.877 140.561 1.00 60.20  ? 207 ILE   A CG1 1 
ATOM   1464 C CG2 . ILE   A 1 181 ? 132.107 140.924 142.794 1.00 68.97  ? 207 ILE   A CG2 1 
ATOM   1465 C CD1 . ILE   A 1 181 ? 134.034 140.493 140.398 1.00 60.54  ? 207 ILE   A CD1 1 
ATOM   1466 N N   . PHE   A 1 182 ? 131.751 137.612 144.465 1.00 58.83  ? 208 PHE   A N   1 
ATOM   1467 C CA  . PHE   A 1 182 ? 131.356 137.371 145.846 1.00 61.66  ? 208 PHE   A CA  1 
ATOM   1468 C C   . PHE   A 1 182 ? 132.484 136.728 146.638 1.00 63.15  ? 208 PHE   A C   1 
ATOM   1469 O O   . PHE   A 1 182 ? 132.709 137.079 147.800 1.00 67.59  ? 208 PHE   A O   1 
ATOM   1470 C CB  . PHE   A 1 182 ? 130.112 136.489 145.895 1.00 68.21  ? 208 PHE   A CB  1 
ATOM   1471 C CG  . PHE   A 1 182 ? 129.809 135.953 147.265 1.00 70.84  ? 208 PHE   A CG  1 
ATOM   1472 C CD1 . PHE   A 1 182 ? 129.240 136.765 148.227 1.00 69.76  ? 208 PHE   A CD1 1 
ATOM   1473 C CD2 . PHE   A 1 182 ? 130.091 134.637 147.588 1.00 69.09  ? 208 PHE   A CD2 1 
ATOM   1474 C CE1 . PHE   A 1 182 ? 128.961 136.278 149.486 1.00 71.25  ? 208 PHE   A CE1 1 
ATOM   1475 C CE2 . PHE   A 1 182 ? 129.813 134.144 148.845 1.00 70.37  ? 208 PHE   A CE2 1 
ATOM   1476 C CZ  . PHE   A 1 182 ? 129.247 134.965 149.795 1.00 73.12  ? 208 PHE   A CZ  1 
ATOM   1477 N N   . ILE   A 1 183 ? 133.190 135.770 146.035 1.00 61.95  ? 209 ILE   A N   1 
ATOM   1478 C CA  . ILE   A 1 183 ? 134.304 135.126 146.721 1.00 60.25  ? 209 ILE   A CA  1 
ATOM   1479 C C   . ILE   A 1 183 ? 135.397 136.140 147.008 1.00 62.41  ? 209 ILE   A C   1 
ATOM   1480 O O   . ILE   A 1 183 ? 135.989 136.136 148.092 1.00 68.96  ? 209 ILE   A O   1 
ATOM   1481 C CB  . ILE   A 1 183 ? 134.826 133.932 145.897 1.00 62.87  ? 209 ILE   A CB  1 
ATOM   1482 C CG1 . ILE   A 1 183 ? 133.824 132.776 145.962 1.00 66.17  ? 209 ILE   A CG1 1 
ATOM   1483 C CG2 . ILE   A 1 183 ? 136.201 133.480 146.399 1.00 64.21  ? 209 ILE   A CG2 1 
ATOM   1484 C CD1 . ILE   A 1 183 ? 134.028 131.707 144.904 1.00 68.14  ? 209 ILE   A CD1 1 
ATOM   1485 N N   . VAL   A 1 184 ? 135.676 137.027 146.049 1.00 60.98  ? 210 VAL   A N   1 
ATOM   1486 C CA  . VAL   A 1 184 ? 136.685 138.063 146.266 1.00 61.33  ? 210 VAL   A CA  1 
ATOM   1487 C C   . VAL   A 1 184 ? 136.323 138.905 147.483 1.00 65.99  ? 210 VAL   A C   1 
ATOM   1488 O O   . VAL   A 1 184 ? 137.110 139.027 148.432 1.00 68.84  ? 210 VAL   A O   1 
ATOM   1489 C CB  . VAL   A 1 184 ? 136.837 138.932 145.002 1.00 58.19  ? 210 VAL   A CB  1 
ATOM   1490 C CG1 . VAL   A 1 184 ? 137.616 140.200 145.297 1.00 59.86  ? 210 VAL   A CG1 1 
ATOM   1491 C CG2 . VAL   A 1 184 ? 137.529 138.151 143.901 1.00 67.86  ? 210 VAL   A CG2 1 
ATOM   1492 N N   . TYR   A 1 185 ? 135.098 139.439 147.503 1.00 67.63  ? 211 TYR   A N   1 
ATOM   1493 C CA  . TYR   A 1 185 ? 134.705 140.325 148.597 1.00 63.05  ? 211 TYR   A CA  1 
ATOM   1494 C C   . TYR   A 1 185 ? 134.668 139.584 149.930 1.00 65.80  ? 211 TYR   A C   1 
ATOM   1495 O O   . TYR   A 1 185 ? 135.177 140.079 150.944 1.00 72.69  ? 211 TYR   A O   1 
ATOM   1496 C CB  . TYR   A 1 185 ? 133.348 140.966 148.302 1.00 66.39  ? 211 TYR   A CB  1 
ATOM   1497 C CG  . TYR   A 1 185 ? 133.401 142.136 147.341 1.00 72.63  ? 211 TYR   A CG  1 
ATOM   1498 C CD1 . TYR   A 1 185 ? 134.058 143.311 147.678 1.00 74.80  ? 211 TYR   A CD1 1 
ATOM   1499 C CD2 . TYR   A 1 185 ? 132.775 142.072 146.106 1.00 72.23  ? 211 TYR   A CD2 1 
ATOM   1500 C CE1 . TYR   A 1 185 ? 134.104 144.379 146.805 1.00 73.98  ? 211 TYR   A CE1 1 
ATOM   1501 C CE2 . TYR   A 1 185 ? 132.813 143.139 145.229 1.00 69.35  ? 211 TYR   A CE2 1 
ATOM   1502 C CZ  . TYR   A 1 185 ? 133.479 144.287 145.584 1.00 72.13  ? 211 TYR   A CZ  1 
ATOM   1503 O OH  . TYR   A 1 185 ? 133.519 145.350 144.713 1.00 79.56  ? 211 TYR   A OH  1 
ATOM   1504 N N   . PHE   A 1 186 ? 134.093 138.381 149.945 1.00 62.19  ? 212 PHE   A N   1 
ATOM   1505 C CA  . PHE   A 1 186 ? 133.910 137.663 151.201 1.00 61.91  ? 212 PHE   A CA  1 
ATOM   1506 C C   . PHE   A 1 186 ? 135.235 137.170 151.766 1.00 63.16  ? 212 PHE   A C   1 
ATOM   1507 O O   . PHE   A 1 186 ? 135.454 137.236 152.981 1.00 72.09  ? 212 PHE   A O   1 
ATOM   1508 C CB  . PHE   A 1 186 ? 132.951 136.494 150.994 1.00 66.22  ? 212 PHE   A CB  1 
ATOM   1509 C CG  . PHE   A 1 186 ? 132.691 135.696 152.236 1.00 70.86  ? 212 PHE   A CG  1 
ATOM   1510 C CD1 . PHE   A 1 186 ? 131.834 136.170 153.212 1.00 75.03  ? 212 PHE   A CD1 1 
ATOM   1511 C CD2 . PHE   A 1 186 ? 133.291 134.464 152.422 1.00 69.69  ? 212 PHE   A CD2 1 
ATOM   1512 C CE1 . PHE   A 1 186 ? 131.588 135.438 154.352 1.00 77.96  ? 212 PHE   A CE1 1 
ATOM   1513 C CE2 . PHE   A 1 186 ? 133.049 133.726 153.560 1.00 74.99  ? 212 PHE   A CE2 1 
ATOM   1514 C CZ  . PHE   A 1 186 ? 132.196 134.213 154.527 1.00 79.51  ? 212 PHE   A CZ  1 
ATOM   1515 N N   . ILE   A 1 187 ? 136.127 136.657 150.917 1.00 57.78  ? 213 ILE   A N   1 
ATOM   1516 C CA  . ILE   A 1 187 ? 137.415 136.194 151.413 1.00 57.98  ? 213 ILE   A CA  1 
ATOM   1517 C C   . ILE   A 1 187 ? 138.255 137.376 151.872 1.00 61.19  ? 213 ILE   A C   1 
ATOM   1518 O O   . ILE   A 1 187 ? 138.989 137.280 152.863 1.00 67.17  ? 213 ILE   A O   1 
ATOM   1519 C CB  . ILE   A 1 187 ? 138.145 135.353 150.349 1.00 60.33  ? 213 ILE   A CB  1 
ATOM   1520 C CG1 . ILE   A 1 187 ? 137.339 134.100 149.971 1.00 62.60  ? 213 ILE   A CG1 1 
ATOM   1521 C CG2 . ILE   A 1 187 ? 139.516 134.939 150.855 1.00 61.47  ? 213 ILE   A CG2 1 
ATOM   1522 C CD1 . ILE   A 1 187 ? 137.318 133.000 151.022 1.00 63.95  ? 213 ILE   A CD1 1 
ATOM   1523 N N   . ALA   A 1 188 ? 138.166 138.512 151.170 1.00 63.36  ? 214 ALA   A N   1 
ATOM   1524 C CA  . ALA   A 1 188 ? 138.857 139.708 151.637 1.00 65.07  ? 214 ALA   A CA  1 
ATOM   1525 C C   . ALA   A 1 188 ? 138.348 140.122 153.011 1.00 63.69  ? 214 ALA   A C   1 
ATOM   1526 O O   . ALA   A 1 188 ? 139.133 140.483 153.895 1.00 69.17  ? 214 ALA   A O   1 
ATOM   1527 C CB  . ALA   A 1 188 ? 138.677 140.843 150.631 1.00 67.74  ? 214 ALA   A CB  1 
ATOM   1528 N N   . GLY   A 1 189 ? 137.030 140.076 153.208 1.00 63.65  ? 215 GLY   A N   1 
ATOM   1529 C CA  . GLY   A 1 189 ? 136.480 140.426 154.507 1.00 66.50  ? 215 GLY   A CA  1 
ATOM   1530 C C   . GLY   A 1 189 ? 136.911 139.477 155.610 1.00 65.34  ? 215 GLY   A C   1 
ATOM   1531 O O   . GLY   A 1 189 ? 137.353 139.911 156.676 1.00 72.09  ? 215 GLY   A O   1 
ATOM   1532 N N   . VAL   A 1 190 ? 136.805 138.169 155.367 1.00 62.80  ? 216 VAL   A N   1 
ATOM   1533 C CA  . VAL   A 1 190 ? 137.082 137.202 156.427 1.00 61.86  ? 216 VAL   A CA  1 
ATOM   1534 C C   . VAL   A 1 190 ? 138.570 137.176 156.757 1.00 68.90  ? 216 VAL   A C   1 
ATOM   1535 O O   . VAL   A 1 190 ? 138.954 136.978 157.915 1.00 75.67  ? 216 VAL   A O   1 
ATOM   1536 C CB  . VAL   A 1 190 ? 136.551 135.805 156.047 1.00 61.82  ? 216 VAL   A CB  1 
ATOM   1537 C CG1 . VAL   A 1 190 ? 137.441 135.132 155.027 1.00 63.15  ? 216 VAL   A CG1 1 
ATOM   1538 C CG2 . VAL   A 1 190 ? 136.423 134.934 157.287 1.00 64.74  ? 216 VAL   A CG2 1 
ATOM   1539 N N   . LYS   A 1 191 ? 139.433 137.365 155.752 1.00 69.56  ? 217 LYS   A N   1 
ATOM   1540 C CA  . LYS   A 1 191 ? 140.865 137.428 156.024 1.00 63.82  ? 217 LYS   A CA  1 
ATOM   1541 C C   . LYS   A 1 191 ? 141.212 138.612 156.914 1.00 64.80  ? 217 LYS   A C   1 
ATOM   1542 O O   . LYS   A 1 191 ? 142.193 138.558 157.663 1.00 73.65  ? 217 LYS   A O   1 
ATOM   1543 C CB  . LYS   A 1 191 ? 141.649 137.506 154.715 1.00 60.27  ? 217 LYS   A CB  1 
ATOM   1544 C CG  . LYS   A 1 191 ? 141.672 136.212 153.918 1.00 65.10  ? 217 LYS   A CG  1 
ATOM   1545 C CD  . LYS   A 1 191 ? 142.631 135.196 154.514 1.00 71.65  ? 217 LYS   A CD  1 
ATOM   1546 C CE  . LYS   A 1 191 ? 142.614 133.896 153.732 1.00 75.59  ? 217 LYS   A CE  1 
ATOM   1547 N NZ  . LYS   A 1 191 ? 143.514 132.876 154.331 1.00 78.96  ? 217 LYS   A NZ  1 
ATOM   1548 N N   . LYS   A 1 192 ? 140.428 139.683 156.850 1.00 64.86  ? 218 LYS   A N   1 
ATOM   1549 C CA  . LYS   A 1 192 ? 140.637 140.858 157.682 1.00 65.29  ? 218 LYS   A CA  1 
ATOM   1550 C C   . LYS   A 1 192 ? 140.100 140.694 159.104 1.00 75.57  ? 218 LYS   A C   1 
ATOM   1551 O O   . LYS   A 1 192 ? 140.049 141.683 159.842 1.00 82.02  ? 218 LYS   A O   1 
ATOM   1552 C CB  . LYS   A 1 192 ? 140.001 142.078 157.013 1.00 69.52  ? 218 LYS   A CB  1 
ATOM   1553 C CG  . LYS   A 1 192 ? 140.771 142.556 155.797 1.00 72.15  ? 218 LYS   A CG  1 
ATOM   1554 C CD  . LYS   A 1 192 ? 140.029 143.644 155.051 1.00 75.51  ? 218 LYS   A CD  1 
ATOM   1555 C CE  . LYS   A 1 192 ? 140.917 144.305 154.013 1.00 80.73  ? 218 LYS   A CE  1 
ATOM   1556 N NZ  . LYS   A 1 192 ? 141.513 143.328 153.066 1.00 76.68  ? 218 LYS   A NZ  1 
ATOM   1557 N N   . LEU   A 1 193 ? 139.710 139.484 159.508 1.00 78.04  ? 219 LEU   A N   1 
ATOM   1558 C CA  . LEU   A 1 193 ? 139.391 139.188 160.906 1.00 78.66  ? 219 LEU   A CA  1 
ATOM   1559 C C   . LEU   A 1 193 ? 140.654 138.741 161.646 1.00 82.29  ? 219 LEU   A C   1 
ATOM   1560 O O   . LEU   A 1 193 ? 140.721 137.668 162.246 1.00 90.81  ? 219 LEU   A O   1 
ATOM   1561 C CB  . LEU   A 1 193 ? 138.297 138.128 160.990 1.00 74.02  ? 219 LEU   A CB  1 
ATOM   1562 C CG  . LEU   A 1 193 ? 136.892 138.534 160.542 1.00 78.21  ? 219 LEU   A CG  1 
ATOM   1563 C CD1 . LEU   A 1 193 ? 135.990 137.314 160.467 1.00 78.96  ? 219 LEU   A CD1 1 
ATOM   1564 C CD2 . LEU   A 1 193 ? 136.293 139.574 161.476 1.00 82.63  ? 219 LEU   A CD2 1 
ATOM   1565 N N   . ASP   A 1 194 ? 141.667 139.601 161.583 1.00 78.02  ? 220 ASP   A N   1 
ATOM   1566 C CA  . ASP   A 1 194 ? 142.964 139.373 162.199 1.00 79.73  ? 220 ASP   A CA  1 
ATOM   1567 C C   . ASP   A 1 194 ? 143.239 140.496 163.188 1.00 83.25  ? 220 ASP   A C   1 
ATOM   1568 O O   . ASP   A 1 194 ? 142.744 141.616 163.029 1.00 85.79  ? 220 ASP   A O   1 
ATOM   1569 C CB  . ASP   A 1 194 ? 144.077 139.304 161.143 1.00 80.83  ? 220 ASP   A CB  1 
ATOM   1570 C CG  . ASP   A 1 194 ? 145.402 138.834 161.714 1.00 91.94  ? 220 ASP   A CG  1 
ATOM   1571 O OD1 . ASP   A 1 194 ? 145.462 138.521 162.922 1.00 91.92  ? 220 ASP   A OD1 1 
ATOM   1572 O OD2 . ASP   A 1 194 ? 146.389 138.776 160.950 1.00 97.96  ? 220 ASP   A OD2 1 
ATOM   1573 N N   . ALA   A 1 195 ? 144.029 140.186 164.218 1.00 81.47  ? 221 ALA   A N   1 
ATOM   1574 C CA  . ALA   A 1 195 ? 144.266 141.143 165.291 1.00 78.15  ? 221 ALA   A CA  1 
ATOM   1575 C C   . ALA   A 1 195 ? 144.959 142.411 164.808 1.00 77.52  ? 221 ALA   A C   1 
ATOM   1576 O O   . ALA   A 1 195 ? 144.833 143.453 165.458 1.00 81.33  ? 221 ALA   A O   1 
ATOM   1577 C CB  . ALA   A 1 195 ? 145.099 140.491 166.395 1.00 81.10  ? 221 ALA   A CB  1 
ATOM   1578 N N   . ASP   A 1 196 ? 145.680 142.353 163.691 1.00 74.76  ? 222 ASP   A N   1 
ATOM   1579 C CA  . ASP   A 1 196 ? 146.415 143.507 163.192 1.00 74.23  ? 222 ASP   A CA  1 
ATOM   1580 C C   . ASP   A 1 196 ? 145.574 144.440 162.330 1.00 74.69  ? 222 ASP   A C   1 
ATOM   1581 O O   . ASP   A 1 196 ? 146.061 145.519 161.976 1.00 81.87  ? 222 ASP   A O   1 
ATOM   1582 C CB  . ASP   A 1 196 ? 147.635 143.045 162.390 1.00 80.46  ? 222 ASP   A CB  1 
ATOM   1583 C CG  . ASP   A 1 196 ? 148.634 142.286 163.237 1.00 87.53  ? 222 ASP   A CG  1 
ATOM   1584 O OD1 . ASP   A 1 196 ? 148.386 142.127 164.450 1.00 87.59  ? 222 ASP   A OD1 1 
ATOM   1585 O OD2 . ASP   A 1 196 ? 149.667 141.847 162.690 1.00 90.61  ? 222 ASP   A OD2 1 
ATOM   1586 N N   . TRP   A 1 197 ? 144.343 144.063 161.984 1.00 72.13  ? 223 TRP   A N   1 
ATOM   1587 C CA  . TRP   A 1 197 ? 143.438 144.918 161.220 1.00 75.34  ? 223 TRP   A CA  1 
ATOM   1588 C C   . TRP   A 1 197 ? 142.302 145.487 162.052 1.00 81.06  ? 223 TRP   A C   1 
ATOM   1589 O O   . TRP   A 1 197 ? 141.969 146.664 161.906 1.00 86.53  ? 223 TRP   A O   1 
ATOM   1590 C CB  . TRP   A 1 197 ? 142.847 144.145 160.038 1.00 76.87  ? 223 TRP   A CB  1 
ATOM   1591 C CG  . TRP   A 1 197 ? 141.978 144.991 159.159 1.00 80.61  ? 223 TRP   A CG  1 
ATOM   1592 C CD1 . TRP   A 1 197 ? 140.620 145.097 159.208 1.00 84.03  ? 223 TRP   A CD1 1 
ATOM   1593 C CD2 . TRP   A 1 197 ? 142.409 145.855 158.102 1.00 77.87  ? 223 TRP   A CD2 1 
ATOM   1594 N NE1 . TRP   A 1 197 ? 140.178 145.971 158.247 1.00 85.65  ? 223 TRP   A NE1 1 
ATOM   1595 C CE2 . TRP   A 1 197 ? 141.258 146.451 157.555 1.00 80.17  ? 223 TRP   A CE2 1 
ATOM   1596 C CE3 . TRP   A 1 197 ? 143.656 146.184 157.565 1.00 82.51  ? 223 TRP   A CE3 1 
ATOM   1597 C CZ2 . TRP   A 1 197 ? 141.315 147.352 156.498 1.00 83.14  ? 223 TRP   A CZ2 1 
ATOM   1598 C CZ3 . TRP   A 1 197 ? 143.709 147.081 156.516 1.00 87.35  ? 223 TRP   A CZ3 1 
ATOM   1599 C CH2 . TRP   A 1 197 ? 142.548 147.654 155.994 1.00 85.46  ? 223 TRP   A CH2 1 
ATOM   1600 N N   . VAL   A 1 198 ? 141.692 144.683 162.926 1.00 80.00  ? 224 VAL   A N   1 
ATOM   1601 C CA  . VAL   A 1 198 ? 140.641 145.200 163.793 1.00 75.76  ? 224 VAL   A CA  1 
ATOM   1602 C C   . VAL   A 1 198 ? 141.191 146.162 164.838 1.00 77.79  ? 224 VAL   A C   1 
ATOM   1603 O O   . VAL   A 1 198 ? 140.426 146.953 165.402 1.00 82.06  ? 224 VAL   A O   1 
ATOM   1604 C CB  . VAL   A 1 198 ? 139.875 144.048 164.476 1.00 74.97  ? 224 VAL   A CB  1 
ATOM   1605 C CG1 . VAL   A 1 198 ? 139.265 143.127 163.434 1.00 77.18  ? 224 VAL   A CG1 1 
ATOM   1606 C CG2 . VAL   A 1 198 ? 140.776 143.265 165.435 1.00 76.95  ? 224 VAL   A CG2 1 
ATOM   1607 N N   . GLU   A 1 199 ? 142.495 146.119 165.114 1.00 75.79  ? 225 GLU   A N   1 
ATOM   1608 C CA  . GLU   A 1 199 ? 143.129 146.996 166.087 1.00 74.59  ? 225 GLU   A CA  1 
ATOM   1609 C C   . GLU   A 1 199 ? 143.763 148.231 165.459 1.00 79.84  ? 225 GLU   A C   1 
ATOM   1610 O O   . GLU   A 1 199 ? 144.326 149.055 166.186 1.00 83.90  ? 225 GLU   A O   1 
ATOM   1611 C CB  . GLU   A 1 199 ? 144.184 146.221 166.877 1.00 78.15  ? 225 GLU   A CB  1 
ATOM   1612 C CG  . GLU   A 1 199 ? 143.609 145.077 167.692 1.00 80.29  ? 225 GLU   A CG  1 
ATOM   1613 C CD  . GLU   A 1 199 ? 144.669 144.319 168.462 1.00 89.60  ? 225 GLU   A CD  1 
ATOM   1614 O OE1 . GLU   A 1 199 ? 145.858 144.679 168.351 1.00 93.58  ? 225 GLU   A OE1 1 
ATOM   1615 O OE2 . GLU   A 1 199 ? 144.312 143.361 169.179 1.00 85.20  ? 225 GLU   A OE2 1 
ATOM   1616 N N   . GLY   A 1 200 ? 143.696 148.379 164.137 1.00 81.67  ? 226 GLY   A N   1 
ATOM   1617 C CA  . GLY   A 1 200 ? 144.093 149.616 163.496 1.00 81.66  ? 226 GLY   A CA  1 
ATOM   1618 C C   . GLY   A 1 200 ? 145.559 149.747 163.157 1.00 84.67  ? 226 GLY   A C   1 
ATOM   1619 O O   . GLY   A 1 200 ? 145.989 150.841 162.773 1.00 90.54  ? 226 GLY   A O   1 
ATOM   1620 N N   . TYR   A 1 201 ? 146.347 148.678 163.282 1.00 79.93  ? 227 TYR   A N   1 
ATOM   1621 C CA  . TYR   A 1 201 ? 147.785 148.800 163.059 1.00 79.39  ? 227 TYR   A CA  1 
ATOM   1622 C C   . TYR   A 1 201 ? 148.115 148.875 161.573 1.00 80.17  ? 227 TYR   A C   1 
ATOM   1623 O O   . TYR   A 1 201 ? 148.875 149.750 161.141 1.00 85.71  ? 227 TYR   A O   1 
ATOM   1624 C CB  . TYR   A 1 201 ? 148.517 147.635 163.721 1.00 78.60  ? 227 TYR   A CB  1 
ATOM   1625 C CG  . TYR   A 1 201 ? 148.555 147.739 165.226 1.00 80.99  ? 227 TYR   A CG  1 
ATOM   1626 C CD1 . TYR   A 1 201 ? 149.470 148.566 165.859 1.00 76.64  ? 227 TYR   A CD1 1 
ATOM   1627 C CD2 . TYR   A 1 201 ? 147.672 147.017 166.014 1.00 84.87  ? 227 TYR   A CD2 1 
ATOM   1628 C CE1 . TYR   A 1 201 ? 149.507 148.668 167.233 1.00 76.49  ? 227 TYR   A CE1 1 
ATOM   1629 C CE2 . TYR   A 1 201 ? 147.703 147.113 167.388 1.00 82.27  ? 227 TYR   A CE2 1 
ATOM   1630 C CZ  . TYR   A 1 201 ? 148.622 147.939 167.992 1.00 80.76  ? 227 TYR   A CZ  1 
ATOM   1631 O OH  . TYR   A 1 201 ? 148.655 148.036 169.363 1.00 86.74  ? 227 TYR   A OH  1 
ATOM   1632 N N   . SER   A 1 202 ? 147.560 147.969 160.773 1.00 71.54  ? 228 SER   A N   1 
ATOM   1633 C CA  . SER   A 1 202 ? 147.858 147.960 159.348 1.00 70.73  ? 228 SER   A CA  1 
ATOM   1634 C C   . SER   A 1 202 ? 147.216 149.162 158.669 1.00 83.03  ? 228 SER   A C   1 
ATOM   1635 O O   . SER   A 1 202 ? 146.030 149.438 158.867 1.00 90.61  ? 228 SER   A O   1 
ATOM   1636 C CB  . SER   A 1 202 ? 147.359 146.665 158.710 1.00 77.52  ? 228 SER   A CB  1 
ATOM   1637 O OG  . SER   A 1 202 ? 147.983 145.536 159.294 1.00 82.37  ? 228 SER   A OG  1 
ATOM   1638 N N   . MET   A 1 203 ? 148.002 149.872 157.857 1.00 87.32  ? 229 MET   A N   1 
ATOM   1639 C CA  . MET   A 1 203 ? 147.537 151.069 157.151 1.00 90.05  ? 229 MET   A CA  1 
ATOM   1640 C C   . MET   A 1 203 ? 147.010 152.116 158.132 1.00 88.89  ? 229 MET   A C   1 
ATOM   1641 O O   . MET   A 1 203 ? 145.913 152.654 157.977 1.00 84.87  ? 229 MET   A O   1 
ATOM   1642 C CB  . MET   A 1 203 ? 146.477 150.715 156.105 1.00 93.12  ? 229 MET   A CB  1 
ATOM   1643 C CG  . MET   A 1 203 ? 147.001 149.847 154.975 1.00 95.98  ? 229 MET   A CG  1 
ATOM   1644 S SD  . MET   A 1 203 ? 146.638 150.512 153.341 1.00 111.45 ? 229 MET   A SD  1 
ATOM   1645 C CE  . MET   A 1 203 ? 147.570 152.043 153.363 1.00 96.72  ? 229 MET   A CE  1 
ATOM   1646 N N   . GLU   A 1 204 ? 147.810 152.396 159.161 1.00 92.11  ? 230 GLU   A N   1 
ATOM   1647 C CA  . GLU   A 1 204 ? 147.442 153.379 160.170 1.00 87.19  ? 230 GLU   A CA  1 
ATOM   1648 C C   . GLU   A 1 204 ? 147.626 154.817 159.703 1.00 87.65  ? 230 GLU   A C   1 
ATOM   1649 O O   . GLU   A 1 204 ? 147.020 155.717 160.294 1.00 93.68  ? 230 GLU   A O   1 
ATOM   1650 C CB  . GLU   A 1 204 ? 148.263 153.147 161.441 1.00 90.64  ? 230 GLU   A CB  1 
ATOM   1651 C CG  . GLU   A 1 204 ? 147.815 153.974 162.635 1.00 98.80  ? 230 GLU   A CG  1 
ATOM   1652 C CD  . GLU   A 1 204 ? 148.530 153.586 163.915 1.00 112.12 ? 230 GLU   A CD  1 
ATOM   1653 O OE1 . GLU   A 1 204 ? 149.430 152.722 163.858 1.00 113.64 ? 230 GLU   A OE1 1 
ATOM   1654 O OE2 . GLU   A 1 204 ? 148.190 154.145 164.979 1.00 115.19 ? 230 GLU   A OE2 1 
ATOM   1655 N N   . TYR   A 1 205 ? 148.422 155.056 158.662 1.00 85.21  ? 231 TYR   A N   1 
ATOM   1656 C CA  . TYR   A 1 205 ? 148.730 156.402 158.197 1.00 88.46  ? 231 TYR   A CA  1 
ATOM   1657 C C   . TYR   A 1 205 ? 147.869 156.832 157.016 1.00 86.08  ? 231 TYR   A C   1 
ATOM   1658 O O   . TYR   A 1 205 ? 148.180 157.840 156.374 1.00 88.39  ? 231 TYR   A O   1 
ATOM   1659 C CB  . TYR   A 1 205 ? 150.212 156.503 157.817 1.00 95.33  ? 231 TYR   A CB  1 
ATOM   1660 C CG  . TYR   A 1 205 ? 151.203 156.241 158.943 1.00 111.43 ? 231 TYR   A CG  1 
ATOM   1661 C CD1 . TYR   A 1 205 ? 150.881 156.499 160.273 1.00 111.94 ? 231 TYR   A CD1 1 
ATOM   1662 C CD2 . TYR   A 1 205 ? 152.471 155.744 158.667 1.00 112.76 ? 231 TYR   A CD2 1 
ATOM   1663 C CE1 . TYR   A 1 205 ? 151.789 156.263 161.289 1.00 111.66 ? 231 TYR   A CE1 1 
ATOM   1664 C CE2 . TYR   A 1 205 ? 153.384 155.505 159.678 1.00 113.08 ? 231 TYR   A CE2 1 
ATOM   1665 C CZ  . TYR   A 1 205 ? 153.038 155.766 160.985 1.00 116.40 ? 231 TYR   A CZ  1 
ATOM   1666 O OH  . TYR   A 1 205 ? 153.946 155.529 161.992 1.00 110.81 ? 231 TYR   A OH  1 
ATOM   1667 N N   . LEU   A 1 206 ? 146.794 156.105 156.718 1.00 85.10  ? 232 LEU   A N   1 
ATOM   1668 C CA  . LEU   A 1 206 ? 145.886 156.479 155.644 1.00 83.02  ? 232 LEU   A CA  1 
ATOM   1669 C C   . LEU   A 1 206 ? 144.844 157.500 156.079 1.00 84.52  ? 232 LEU   A C   1 
ATOM   1670 O O   . LEU   A 1 206 ? 144.139 158.043 155.222 1.00 90.09  ? 232 LEU   A O   1 
ATOM   1671 C CB  . LEU   A 1 206 ? 145.185 155.226 155.103 1.00 88.64  ? 232 LEU   A CB  1 
ATOM   1672 C CG  . LEU   A 1 206 ? 144.331 155.341 153.835 1.00 97.41  ? 232 LEU   A CG  1 
ATOM   1673 C CD1 . LEU   A 1 206 ? 145.156 155.830 152.652 1.00 93.24  ? 232 LEU   A CD1 1 
ATOM   1674 C CD2 . LEU   A 1 206 ? 143.686 154.003 153.515 1.00 98.25  ? 232 LEU   A CD2 1 
ATOM   1675 N N   . SER   A 1 207 ? 144.740 157.794 157.376 1.00 86.83  ? 233 SER   A N   1 
ATOM   1676 C CA  . SER   A 1 207 ? 143.731 158.721 157.869 1.00 93.34  ? 233 SER   A CA  1 
ATOM   1677 C C   . SER   A 1 207 ? 144.139 160.183 157.736 1.00 92.94  ? 233 SER   A C   1 
ATOM   1678 O O   . SER   A 1 207 ? 143.295 161.060 157.949 1.00 97.72  ? 233 SER   A O   1 
ATOM   1679 C CB  . SER   A 1 207 ? 143.420 158.415 159.335 1.00 96.30  ? 233 SER   A CB  1 
ATOM   1680 O OG  . SER   A 1 207 ? 142.388 159.253 159.828 1.00 100.71 ? 233 SER   A OG  1 
ATOM   1681 N N   . ARG   A 1 208 ? 145.391 160.470 157.387 1.00 87.31  ? 234 ARG   A N   1 
ATOM   1682 C CA  . ARG   A 1 208 ? 145.853 161.839 157.208 1.00 87.89  ? 234 ARG   A CA  1 
ATOM   1683 C C   . ARG   A 1 208 ? 145.641 162.362 155.794 1.00 85.28  ? 234 ARG   A C   1 
ATOM   1684 O O   . ARG   A 1 208 ? 145.892 163.546 155.548 1.00 91.35  ? 234 ARG   A O   1 
ATOM   1685 C CB  . ARG   A 1 208 ? 147.339 161.944 157.565 1.00 98.14  ? 234 ARG   A CB  1 
ATOM   1686 C CG  . ARG   A 1 208 ? 147.650 161.649 159.023 1.00 105.12 ? 234 ARG   A CG  1 
ATOM   1687 C CD  . ARG   A 1 208 ? 149.147 161.635 159.283 1.00 109.03 ? 234 ARG   A CD  1 
ATOM   1688 N NE  . ARG   A 1 208 ? 149.465 161.206 160.640 1.00 117.32 ? 234 ARG   A NE  1 
ATOM   1689 C CZ  . ARG   A 1 208 ? 150.693 161.053 161.121 1.00 122.94 ? 234 ARG   A CZ  1 
ATOM   1690 N NH1 . ARG   A 1 208 ? 151.766 161.291 160.382 1.00 126.67 ? 234 ARG   A NH1 1 
ATOM   1691 N NH2 . ARG   A 1 208 ? 150.850 160.650 162.379 1.00 123.59 ? 234 ARG   A NH2 1 
ATOM   1692 N N   . HIS   A 1 209 ? 145.195 161.521 154.866 1.00 83.08  ? 235 HIS   A N   1 
ATOM   1693 C CA  . HIS   A 1 209 ? 144.977 161.958 153.496 1.00 86.85  ? 235 HIS   A CA  1 
ATOM   1694 C C   . HIS   A 1 209 ? 143.854 162.987 153.439 1.00 92.97  ? 235 HIS   A C   1 
ATOM   1695 O O   . HIS   A 1 209 ? 142.915 162.959 154.239 1.00 99.04  ? 235 HIS   A O   1 
ATOM   1696 C CB  . HIS   A 1 209 ? 144.637 160.762 152.609 1.00 87.18  ? 235 HIS   A CB  1 
ATOM   1697 C CG  . HIS   A 1 209 ? 145.055 160.928 151.184 1.00 89.89  ? 235 HIS   A CG  1 
ATOM   1698 N ND1 . HIS   A 1 209 ? 144.373 161.731 150.297 1.00 93.17  ? 235 HIS   A ND1 1 
ATOM   1699 C CD2 . HIS   A 1 209 ? 146.084 160.388 150.489 1.00 95.45  ? 235 HIS   A CD2 1 
ATOM   1700 C CE1 . HIS   A 1 209 ? 144.965 161.681 149.117 1.00 97.40  ? 235 HIS   A CE1 1 
ATOM   1701 N NE2 . HIS   A 1 209 ? 146.006 160.874 149.207 1.00 98.73  ? 235 HIS   A NE2 1 
ATOM   1702 N N   . TRP   A 1 210 ? 143.958 163.908 152.479 1.00 87.60  ? 236 TRP   A N   1 
ATOM   1703 C CA  . TRP   A 1 210 ? 142.965 164.973 152.379 1.00 88.95  ? 236 TRP   A CA  1 
ATOM   1704 C C   . TRP   A 1 210 ? 141.588 164.457 151.980 1.00 92.39  ? 236 TRP   A C   1 
ATOM   1705 O O   . TRP   A 1 210 ? 140.593 165.146 152.222 1.00 94.90  ? 236 TRP   A O   1 
ATOM   1706 C CB  . TRP   A 1 210 ? 143.427 166.050 151.392 1.00 90.01  ? 236 TRP   A CB  1 
ATOM   1707 C CG  . TRP   A 1 210 ? 143.649 165.572 149.991 1.00 92.62  ? 236 TRP   A CG  1 
ATOM   1708 C CD1 . TRP   A 1 210 ? 144.797 165.046 149.479 1.00 96.07  ? 236 TRP   A CD1 1 
ATOM   1709 C CD2 . TRP   A 1 210 ? 142.702 165.591 148.917 1.00 95.10  ? 236 TRP   A CD2 1 
ATOM   1710 N NE1 . TRP   A 1 210 ? 144.624 164.729 148.155 1.00 96.90  ? 236 TRP   A NE1 1 
ATOM   1711 C CE2 . TRP   A 1 210 ? 143.347 165.056 147.784 1.00 95.47  ? 236 TRP   A CE2 1 
ATOM   1712 C CE3 . TRP   A 1 210 ? 141.373 166.008 148.802 1.00 98.30  ? 236 TRP   A CE3 1 
ATOM   1713 C CZ2 . TRP   A 1 210 ? 142.707 164.923 146.555 1.00 95.47  ? 236 TRP   A CZ2 1 
ATOM   1714 C CZ3 . TRP   A 1 210 ? 140.740 165.876 147.580 1.00 100.51 ? 236 TRP   A CZ3 1 
ATOM   1715 C CH2 . TRP   A 1 210 ? 141.407 165.338 146.473 1.00 97.61  ? 236 TRP   A CH2 1 
ATOM   1716 N N   . LEU   A 1 211 ? 141.502 163.269 151.375 1.00 95.66  ? 237 LEU   A N   1 
ATOM   1717 C CA  . LEU   A 1 211 ? 140.195 162.706 151.049 1.00 93.31  ? 237 LEU   A CA  1 
ATOM   1718 C C   . LEU   A 1 211 ? 139.390 162.388 152.303 1.00 91.77  ? 237 LEU   A C   1 
ATOM   1719 O O   . LEU   A 1 211 ? 138.156 162.375 152.256 1.00 93.65  ? 237 LEU   A O   1 
ATOM   1720 C CB  . LEU   A 1 211 ? 140.357 161.450 150.192 1.00 90.80  ? 237 LEU   A CB  1 
ATOM   1721 C CG  . LEU   A 1 211 ? 140.881 161.649 148.767 1.00 95.54  ? 237 LEU   A CG  1 
ATOM   1722 C CD1 . LEU   A 1 211 ? 141.224 160.301 148.155 1.00 98.20  ? 237 LEU   A CD1 1 
ATOM   1723 C CD2 . LEU   A 1 211 ? 139.874 162.389 147.891 1.00 94.05  ? 237 LEU   A CD2 1 
ATOM   1724 N N   . PHE   A 1 212 ? 140.061 162.129 153.423 1.00 87.10  ? 238 PHE   A N   1 
ATOM   1725 C CA  . PHE   A 1 212 ? 139.401 161.916 154.702 1.00 89.75  ? 238 PHE   A CA  1 
ATOM   1726 C C   . PHE   A 1 212 ? 139.180 163.212 155.474 1.00 93.56  ? 238 PHE   A C   1 
ATOM   1727 O O   . PHE   A 1 212 ? 138.752 163.162 156.632 1.00 97.22  ? 238 PHE   A O   1 
ATOM   1728 C CB  . PHE   A 1 212 ? 140.216 160.942 155.553 1.00 93.62  ? 238 PHE   A CB  1 
ATOM   1729 C CG  . PHE   A 1 212 ? 140.243 159.545 155.013 1.00 93.00  ? 238 PHE   A CG  1 
ATOM   1730 C CD1 . PHE   A 1 212 ? 141.208 159.156 154.104 1.00 92.50  ? 238 PHE   A CD1 1 
ATOM   1731 C CD2 . PHE   A 1 212 ? 139.302 158.617 155.419 1.00 92.07  ? 238 PHE   A CD2 1 
ATOM   1732 C CE1 . PHE   A 1 212 ? 141.233 157.871 153.610 1.00 91.85  ? 238 PHE   A CE1 1 
ATOM   1733 C CE2 . PHE   A 1 212 ? 139.323 157.333 154.928 1.00 92.96  ? 238 PHE   A CE2 1 
ATOM   1734 C CZ  . PHE   A 1 212 ? 140.290 156.960 154.022 1.00 92.64  ? 238 PHE   A CZ  1 
ATOM   1735 N N   . SER   A 1 213 ? 139.468 164.364 154.865 1.00 98.22  ? 239 SER   A N   1 
ATOM   1736 C CA  . SER   A 1 213 ? 139.239 165.646 155.529 1.00 102.30 ? 239 SER   A CA  1 
ATOM   1737 C C   . SER   A 1 213 ? 137.796 165.855 155.982 1.00 100.81 ? 239 SER   A C   1 
ATOM   1738 O O   . SER   A 1 213 ? 137.602 166.320 157.119 1.00 101.40 ? 239 SER   A O   1 
ATOM   1739 C CB  . SER   A 1 213 ? 139.695 166.781 154.606 1.00 103.56 ? 239 SER   A CB  1 
ATOM   1740 O OG  . SER   A 1 213 ? 139.291 166.556 153.268 1.00 107.34 ? 239 SER   A OG  1 
ATOM   1741 N N   . PRO   A 1 214 ? 136.754 165.575 155.180 1.00 95.53  ? 240 PRO   A N   1 
ATOM   1742 C CA  . PRO   A 1 214 ? 135.393 165.811 155.697 1.00 93.80  ? 240 PRO   A CA  1 
ATOM   1743 C C   . PRO   A 1 214 ? 135.041 164.964 156.905 1.00 94.77  ? 240 PRO   A C   1 
ATOM   1744 O O   . PRO   A 1 214 ? 134.281 165.417 157.770 1.00 102.38 ? 240 PRO   A O   1 
ATOM   1745 C CB  . PRO   A 1 214 ? 134.493 165.492 154.495 1.00 92.87  ? 240 PRO   A CB  1 
ATOM   1746 C CG  . PRO   A 1 214 ? 135.308 164.666 153.606 1.00 95.33  ? 240 PRO   A CG  1 
ATOM   1747 C CD  . PRO   A 1 214 ? 136.708 165.146 153.768 1.00 97.41  ? 240 PRO   A CD  1 
ATOM   1748 N N   . PHE   A 1 215 ? 135.566 163.741 156.991 1.00 89.22  ? 241 PHE   A N   1 
ATOM   1749 C CA  . PHE   A 1 215 ? 135.296 162.912 158.159 1.00 89.81  ? 241 PHE   A CA  1 
ATOM   1750 C C   . PHE   A 1 215 ? 135.862 163.535 159.427 1.00 93.99  ? 241 PHE   A C   1 
ATOM   1751 O O   . PHE   A 1 215 ? 135.253 163.422 160.497 1.00 96.22  ? 241 PHE   A O   1 
ATOM   1752 C CB  . PHE   A 1 215 ? 135.867 161.511 157.954 1.00 94.45  ? 241 PHE   A CB  1 
ATOM   1753 C CG  . PHE   A 1 215 ? 135.127 160.701 156.932 1.00 96.58  ? 241 PHE   A CG  1 
ATOM   1754 C CD1 . PHE   A 1 215 ? 135.484 160.753 155.597 1.00 99.74  ? 241 PHE   A CD1 1 
ATOM   1755 C CD2 . PHE   A 1 215 ? 134.071 159.891 157.306 1.00 100.02 ? 241 PHE   A CD2 1 
ATOM   1756 C CE1 . PHE   A 1 215 ? 134.803 160.011 154.656 1.00 104.33 ? 241 PHE   A CE1 1 
ATOM   1757 C CE2 . PHE   A 1 215 ? 133.386 159.147 156.369 1.00 107.51 ? 241 PHE   A CE2 1 
ATOM   1758 C CZ  . PHE   A 1 215 ? 133.753 159.207 155.041 1.00 107.87 ? 241 PHE   A CZ  1 
ATOM   1759 N N   . LYS   A 1 216 ? 137.014 164.203 159.330 1.00 99.94  ? 242 LYS   A N   1 
ATOM   1760 C CA  . LYS   A 1 216 ? 137.643 164.781 160.512 1.00 103.94 ? 242 LYS   A CA  1 
ATOM   1761 C C   . LYS   A 1 216 ? 136.828 165.917 161.116 1.00 103.76 ? 242 LYS   A C   1 
ATOM   1762 O O   . LYS   A 1 216 ? 137.070 166.287 162.270 1.00 103.13 ? 242 LYS   A O   1 
ATOM   1763 C CB  . LYS   A 1 216 ? 139.044 165.290 160.174 1.00 103.17 ? 242 LYS   A CB  1 
ATOM   1764 C CG  . LYS   A 1 216 ? 140.029 164.197 159.809 1.00 100.96 ? 242 LYS   A CG  1 
ATOM   1765 C CD  . LYS   A 1 216 ? 141.409 164.769 159.532 1.00 107.77 ? 242 LYS   A CD  1 
ATOM   1766 C CE  . LYS   A 1 216 ? 142.362 163.701 159.026 1.00 107.66 ? 242 LYS   A CE  1 
ATOM   1767 N NZ  . LYS   A 1 216 ? 142.525 162.581 159.994 1.00 105.32 ? 242 LYS   A NZ  1 
ATOM   1768 N N   . LEU   A 1 217 ? 135.877 166.483 160.368 1.00 99.58  ? 243 LEU   A N   1 
ATOM   1769 C CA  . LEU   A 1 217 ? 135.071 167.575 160.902 1.00 100.31 ? 243 LEU   A CA  1 
ATOM   1770 C C   . LEU   A 1 217 ? 134.236 167.129 162.095 1.00 99.24  ? 243 LEU   A C   1 
ATOM   1771 O O   . LEU   A 1 217 ? 133.897 167.954 162.952 1.00 103.33 ? 243 LEU   A O   1 
ATOM   1772 C CB  . LEU   A 1 217 ? 134.169 168.142 159.805 1.00 99.93  ? 243 LEU   A CB  1 
ATOM   1773 C CG  . LEU   A 1 217 ? 134.857 168.590 158.513 1.00 100.16 ? 243 LEU   A CG  1 
ATOM   1774 C CD1 . LEU   A 1 217 ? 133.825 169.087 157.514 1.00 102.01 ? 243 LEU   A CD1 1 
ATOM   1775 C CD2 . LEU   A 1 217 ? 135.898 169.666 158.786 1.00 97.56  ? 243 LEU   A CD2 1 
ATOM   1776 N N   . LEU   A 1 218 ? 133.898 165.835 162.171 1.00 95.25  ? 244 LEU   A N   1 
ATOM   1777 C CA  . LEU   A 1 218 ? 133.092 165.287 163.254 1.00 98.17  ? 244 LEU   A CA  1 
ATOM   1778 C C   . LEU   A 1 218 ? 133.834 164.301 164.143 1.00 97.99  ? 244 LEU   A C   1 
ATOM   1779 O O   . LEU   A 1 218 ? 133.362 164.038 165.254 1.00 98.84  ? 244 LEU   A O   1 
ATOM   1780 C CB  . LEU   A 1 218 ? 131.847 164.577 162.693 1.00 103.96 ? 244 LEU   A CB  1 
ATOM   1781 C CG  . LEU   A 1 218 ? 130.719 165.396 162.044 1.00 109.81 ? 244 LEU   A CG  1 
ATOM   1782 C CD1 . LEU   A 1 218 ? 130.171 166.452 162.998 1.00 107.41 ? 244 LEU   A CD1 1 
ATOM   1783 C CD2 . LEU   A 1 218 ? 131.157 166.035 160.730 1.00 106.43 ? 244 LEU   A CD2 1 
ATOM   1784 N N   . LEU   A 1 219 ? 134.967 163.754 163.698 1.00 101.97 ? 245 LEU   A N   1 
ATOM   1785 C CA  . LEU   A 1 219 ? 135.707 162.739 164.437 1.00 101.32 ? 245 LEU   A CA  1 
ATOM   1786 C C   . LEU   A 1 219 ? 137.175 163.127 164.538 1.00 96.51  ? 245 LEU   A C   1 
ATOM   1787 O O   . LEU   A 1 219 ? 137.720 163.799 163.659 1.00 101.67 ? 245 LEU   A O   1 
ATOM   1788 C CB  . LEU   A 1 219 ? 135.596 161.360 163.769 1.00 97.94  ? 245 LEU   A CB  1 
ATOM   1789 C CG  . LEU   A 1 219 ? 134.198 160.749 163.659 1.00 103.30 ? 245 LEU   A CG  1 
ATOM   1790 C CD1 . LEU   A 1 219 ? 134.258 159.457 162.864 1.00 101.69 ? 245 LEU   A CD1 1 
ATOM   1791 C CD2 . LEU   A 1 219 ? 133.594 160.502 165.034 1.00 101.33 ? 245 LEU   A CD2 1 
ATOM   1792 N N   . SER   A 1 220 ? 137.806 162.701 165.627 1.00 85.41  ? 246 SER   A N   1 
ATOM   1793 C CA  . SER   A 1 220 ? 139.240 162.875 165.779 1.00 85.55  ? 246 SER   A CA  1 
ATOM   1794 C C   . SER   A 1 220 ? 139.990 161.938 164.836 1.00 93.86  ? 246 SER   A C   1 
ATOM   1795 O O   . SER   A 1 220 ? 139.449 160.948 164.337 1.00 98.93  ? 246 SER   A O   1 
ATOM   1796 C CB  . SER   A 1 220 ? 139.660 162.614 167.223 1.00 92.51  ? 246 SER   A CB  1 
ATOM   1797 O OG  . SER   A 1 220 ? 139.178 161.360 167.674 1.00 96.54  ? 246 SER   A OG  1 
ATOM   1798 N N   . GLU   A 1 221 ? 141.260 162.272 164.592 1.00 96.55  ? 247 GLU   A N   1 
ATOM   1799 C CA  . GLU   A 1 221 ? 142.068 161.491 163.659 1.00 96.54  ? 247 GLU   A CA  1 
ATOM   1800 C C   . GLU   A 1 221 ? 142.263 160.062 164.151 1.00 94.50  ? 247 GLU   A C   1 
ATOM   1801 O O   . GLU   A 1 221 ? 142.203 159.113 163.360 1.00 97.60  ? 247 GLU   A O   1 
ATOM   1802 C CB  . GLU   A 1 221 ? 143.418 162.181 163.448 1.00 92.49  ? 247 GLU   A CB  1 
ATOM   1803 C CG  . GLU   A 1 221 ? 144.406 161.412 162.575 1.00 95.95  ? 247 GLU   A CG  1 
ATOM   1804 C CD  . GLU   A 1 221 ? 145.650 162.219 162.247 1.00 110.06 ? 247 GLU   A CD  1 
ATOM   1805 O OE1 . GLU   A 1 221 ? 145.595 163.465 162.309 1.00 110.09 ? 247 GLU   A OE1 1 
ATOM   1806 O OE2 . GLU   A 1 221 ? 146.689 161.602 161.932 1.00 118.93 ? 247 GLU   A OE2 1 
ATOM   1807 N N   . GLU   A 1 222 ? 142.512 159.890 165.451 1.00 91.48  ? 248 GLU   A N   1 
ATOM   1808 C CA  . GLU   A 1 222 ? 142.800 158.560 165.981 1.00 94.00  ? 248 GLU   A CA  1 
ATOM   1809 C C   . GLU   A 1 222 ? 141.606 157.625 165.819 1.00 95.56  ? 248 GLU   A C   1 
ATOM   1810 O O   . GLU   A 1 222 ? 141.766 156.458 165.444 1.00 100.06 ? 248 GLU   A O   1 
ATOM   1811 C CB  . GLU   A 1 222 ? 143.235 158.655 167.448 1.00 100.34 ? 248 GLU   A CB  1 
ATOM   1812 C CG  . GLU   A 1 222 ? 142.268 159.368 168.386 1.00 107.09 ? 248 GLU   A CG  1 
ATOM   1813 C CD  . GLU   A 1 222 ? 142.772 159.404 169.816 1.00 115.32 ? 248 GLU   A CD  1 
ATOM   1814 O OE1 . GLU   A 1 222 ? 143.864 158.858 170.076 1.00 120.43 ? 248 GLU   A OE1 1 
ATOM   1815 O OE2 . GLU   A 1 222 ? 142.076 159.979 170.679 1.00 110.60 ? 248 GLU   A OE2 1 
ATOM   1816 N N   . LEU   A 1 223 ? 140.396 158.117 166.096 1.00 91.53  ? 249 LEU   A N   1 
ATOM   1817 C CA  . LEU   A 1 223 ? 139.209 157.295 165.878 1.00 88.61  ? 249 LEU   A CA  1 
ATOM   1818 C C   . LEU   A 1 223 ? 138.896 157.145 164.395 1.00 90.63  ? 249 LEU   A C   1 
ATOM   1819 O O   . LEU   A 1 223 ? 138.373 156.106 163.976 1.00 93.39  ? 249 LEU   A O   1 
ATOM   1820 C CB  . LEU   A 1 223 ? 138.003 157.889 166.605 1.00 90.24  ? 249 LEU   A CB  1 
ATOM   1821 C CG  . LEU   A 1 223 ? 137.792 157.471 168.064 1.00 93.17  ? 249 LEU   A CG  1 
ATOM   1822 C CD1 . LEU   A 1 223 ? 138.836 158.084 168.988 1.00 96.13  ? 249 LEU   A CD1 1 
ATOM   1823 C CD2 . LEU   A 1 223 ? 136.386 157.830 168.521 1.00 93.99  ? 249 LEU   A CD2 1 
ATOM   1824 N N   . THR   A 1 224 ? 139.179 158.175 163.595 1.00 91.09  ? 250 THR   A N   1 
ATOM   1825 C CA  . THR   A 1 224 ? 138.931 158.085 162.160 1.00 87.66  ? 250 THR   A CA  1 
ATOM   1826 C C   . THR   A 1 224 ? 139.825 157.043 161.503 1.00 88.51  ? 250 THR   A C   1 
ATOM   1827 O O   . THR   A 1 224 ? 139.446 156.459 160.482 1.00 94.86  ? 250 THR   A O   1 
ATOM   1828 C CB  . THR   A 1 224 ? 139.139 159.450 161.504 1.00 88.25  ? 250 THR   A CB  1 
ATOM   1829 O OG1 . THR   A 1 224 ? 138.216 160.393 162.060 1.00 90.36  ? 250 THR   A OG1 1 
ATOM   1830 C CG2 . THR   A 1 224 ? 138.928 159.365 160.002 1.00 91.35  ? 250 THR   A CG2 1 
ATOM   1831 N N   . SER   A 1 225 ? 141.002 156.792 162.070 1.00 87.27  ? 251 SER   A N   1 
ATOM   1832 C CA  . SER   A 1 225 ? 141.894 155.773 161.535 1.00 84.56  ? 251 SER   A CA  1 
ATOM   1833 C C   . SER   A 1 225 ? 141.462 154.356 161.883 1.00 82.83  ? 251 SER   A C   1 
ATOM   1834 O O   . SER   A 1 225 ? 142.036 153.411 161.335 1.00 89.28  ? 251 SER   A O   1 
ATOM   1835 C CB  . SER   A 1 225 ? 143.316 156.000 162.048 1.00 90.54  ? 251 SER   A CB  1 
ATOM   1836 O OG  . SER   A 1 225 ? 144.174 154.950 161.638 1.00 93.93  ? 251 SER   A OG  1 
ATOM   1837 N N   . LEU   A 1 226 ? 140.478 154.183 162.767 1.00 79.67  ? 252 LEU   A N   1 
ATOM   1838 C CA  . LEU   A 1 226 ? 140.019 152.871 163.207 1.00 85.29  ? 252 LEU   A CA  1 
ATOM   1839 C C   . LEU   A 1 226 ? 138.598 152.562 162.762 1.00 89.91  ? 252 LEU   A C   1 
ATOM   1840 O O   . LEU   A 1 226 ? 138.356 151.522 162.142 1.00 94.88  ? 252 LEU   A O   1 
ATOM   1841 C CB  . LEU   A 1 226 ? 140.115 152.780 164.738 1.00 88.16  ? 252 LEU   A CB  1 
ATOM   1842 C CG  . LEU   A 1 226 ? 139.758 151.450 165.409 1.00 88.39  ? 252 LEU   A CG  1 
ATOM   1843 C CD1 . LEU   A 1 226 ? 140.653 150.323 164.924 1.00 85.95  ? 252 LEU   A CD1 1 
ATOM   1844 C CD2 . LEU   A 1 226 ? 139.856 151.597 166.915 1.00 86.74  ? 252 LEU   A CD2 1 
ATOM   1845 N N   . LEU   A 1 227 ? 137.644 153.443 163.066 1.00 91.11  ? 253 LEU   A N   1 
ATOM   1846 C CA  . LEU   A 1 227 ? 136.250 153.168 162.732 1.00 88.04  ? 253 LEU   A CA  1 
ATOM   1847 C C   . LEU   A 1 227 ? 136.014 153.211 161.227 1.00 85.24  ? 253 LEU   A C   1 
ATOM   1848 O O   . LEU   A 1 227 ? 135.271 152.384 160.687 1.00 87.44  ? 253 LEU   A O   1 
ATOM   1849 C CB  . LEU   A 1 227 ? 135.334 154.170 163.435 1.00 86.16  ? 253 LEU   A CB  1 
ATOM   1850 C CG  . LEU   A 1 227 ? 135.387 154.211 164.962 1.00 90.06  ? 253 LEU   A CG  1 
ATOM   1851 C CD1 . LEU   A 1 227 ? 134.489 155.319 165.481 1.00 88.92  ? 253 LEU   A CD1 1 
ATOM   1852 C CD2 . LEU   A 1 227 ? 134.988 152.874 165.565 1.00 89.40  ? 253 LEU   A CD2 1 
ATOM   1853 N N   . VAL   A 1 228 ? 136.628 154.167 160.537 1.00 82.52  ? 254 VAL   A N   1 
ATOM   1854 C CA  . VAL   A 1 228 ? 136.322 154.422 159.135 1.00 86.81  ? 254 VAL   A CA  1 
ATOM   1855 C C   . VAL   A 1 228 ? 137.159 153.516 158.243 1.00 88.85  ? 254 VAL   A C   1 
ATOM   1856 O O   . VAL   A 1 228 ? 136.619 152.771 157.417 1.00 93.22  ? 254 VAL   A O   1 
ATOM   1857 C CB  . VAL   A 1 228 ? 136.551 155.903 158.781 1.00 92.09  ? 254 VAL   A CB  1 
ATOM   1858 C CG1 . VAL   A 1 228 ? 136.253 156.156 157.308 1.00 95.39  ? 254 VAL   A CG1 1 
ATOM   1859 C CG2 . VAL   A 1 228 ? 135.700 156.804 159.671 1.00 97.64  ? 254 VAL   A CG2 1 
ATOM   1860 N N   . VAL   A 1 229 ? 138.481 153.576 158.395 1.00 83.25  ? 255 VAL   A N   1 
ATOM   1861 C CA  . VAL   A 1 229 ? 139.367 152.894 157.456 1.00 79.91  ? 255 VAL   A CA  1 
ATOM   1862 C C   . VAL   A 1 229 ? 139.257 151.380 157.611 1.00 83.77  ? 255 VAL   A C   1 
ATOM   1863 O O   . VAL   A 1 229 ? 139.093 150.653 156.624 1.00 92.34  ? 255 VAL   A O   1 
ATOM   1864 C CB  . VAL   A 1 229 ? 140.817 153.378 157.638 1.00 78.42  ? 255 VAL   A CB  1 
ATOM   1865 C CG1 . VAL   A 1 229 ? 141.729 152.749 156.593 1.00 83.95  ? 255 VAL   A CG1 1 
ATOM   1866 C CG2 . VAL   A 1 229 ? 140.883 154.901 157.564 1.00 87.26  ? 255 VAL   A CG2 1 
ATOM   1867 N N   . HIS   A 1 230 ? 139.338 150.882 158.845 1.00 80.20  ? 256 HIS   A N   1 
ATOM   1868 C CA  . HIS   A 1 230 ? 139.445 149.444 159.084 1.00 78.99  ? 256 HIS   A CA  1 
ATOM   1869 C C   . HIS   A 1 230 ? 138.084 148.770 159.232 1.00 80.71  ? 256 HIS   A C   1 
ATOM   1870 O O   . HIS   A 1 230 ? 137.738 147.866 158.460 1.00 88.58  ? 256 HIS   A O   1 
ATOM   1871 C CB  . HIS   A 1 230 ? 140.284 149.188 160.339 1.00 83.34  ? 256 HIS   A CB  1 
ATOM   1872 C CG  . HIS   A 1 230 ? 141.711 149.618 160.213 1.00 86.68  ? 256 HIS   A CG  1 
ATOM   1873 N ND1 . HIS   A 1 230 ? 142.096 150.940 160.246 1.00 85.91  ? 256 HIS   A ND1 1 
ATOM   1874 C CD2 . HIS   A 1 230 ? 142.846 148.899 160.054 1.00 86.99  ? 256 HIS   A CD2 1 
ATOM   1875 C CE1 . HIS   A 1 230 ? 143.408 151.016 160.113 1.00 83.57  ? 256 HIS   A CE1 1 
ATOM   1876 N NE2 . HIS   A 1 230 ? 143.887 149.792 159.997 1.00 84.98  ? 256 HIS   A NE2 1 
ATOM   1877 N N   . TRP   A 1 231 ? 137.306 149.198 160.229 1.00 76.53  ? 257 TRP   A N   1 
ATOM   1878 C CA  . TRP   A 1 231 ? 136.004 148.584 160.456 1.00 78.83  ? 257 TRP   A CA  1 
ATOM   1879 C C   . TRP   A 1 231 ? 135.077 148.844 159.280 1.00 84.45  ? 257 TRP   A C   1 
ATOM   1880 O O   . TRP   A 1 231 ? 134.310 147.960 158.874 1.00 85.30  ? 257 TRP   A O   1 
ATOM   1881 C CB  . TRP   A 1 231 ? 135.387 149.113 161.749 1.00 77.89  ? 257 TRP   A CB  1 
ATOM   1882 C CG  . TRP   A 1 231 ? 136.070 148.657 163.006 1.00 80.83  ? 257 TRP   A CG  1 
ATOM   1883 C CD1 . TRP   A 1 231 ? 137.269 148.015 163.113 1.00 84.20  ? 257 TRP   A CD1 1 
ATOM   1884 C CD2 . TRP   A 1 231 ? 135.577 148.806 164.341 1.00 91.01  ? 257 TRP   A CD2 1 
ATOM   1885 N NE1 . TRP   A 1 231 ? 137.554 147.760 164.430 1.00 88.81  ? 257 TRP   A NE1 1 
ATOM   1886 C CE2 . TRP   A 1 231 ? 136.530 148.235 165.205 1.00 89.29  ? 257 TRP   A CE2 1 
ATOM   1887 C CE3 . TRP   A 1 231 ? 134.421 149.369 164.889 1.00 97.98  ? 257 TRP   A CE3 1 
ATOM   1888 C CZ2 . TRP   A 1 231 ? 136.364 148.211 166.586 1.00 91.43  ? 257 TRP   A CZ2 1 
ATOM   1889 C CZ3 . TRP   A 1 231 ? 134.258 149.345 166.260 1.00 100.91 ? 257 TRP   A CZ3 1 
ATOM   1890 C CH2 . TRP   A 1 231 ? 135.224 148.769 167.093 1.00 98.19  ? 257 TRP   A CH2 1 
ATOM   1891 N N   . GLY   A 1 232 ? 135.137 150.054 158.723 1.00 84.58  ? 258 GLY   A N   1 
ATOM   1892 C CA  . GLY   A 1 232 ? 134.409 150.328 157.501 1.00 81.09  ? 258 GLY   A CA  1 
ATOM   1893 C C   . GLY   A 1 232 ? 134.832 149.414 156.370 1.00 79.38  ? 258 GLY   A C   1 
ATOM   1894 O O   . GLY   A 1 232 ? 133.997 148.947 155.599 1.00 86.39  ? 258 GLY   A O   1 
ATOM   1895 N N   . GLY   A 1 233 ? 136.130 149.125 156.274 1.00 74.59  ? 259 GLY   A N   1 
ATOM   1896 C CA  . GLY   A 1 233 ? 136.602 148.227 155.232 1.00 76.97  ? 259 GLY   A CA  1 
ATOM   1897 C C   . GLY   A 1 233 ? 136.039 146.825 155.371 1.00 75.83  ? 259 GLY   A C   1 
ATOM   1898 O O   . GLY   A 1 233 ? 135.560 146.235 154.399 1.00 86.33  ? 259 GLY   A O   1 
ATOM   1899 N N   . LEU   A 1 234 ? 136.076 146.279 156.587 1.00 73.45  ? 260 LEU   A N   1 
ATOM   1900 C CA  . LEU   A 1 234 ? 135.558 144.929 156.806 1.00 76.10  ? 260 LEU   A CA  1 
ATOM   1901 C C   . LEU   A 1 234 ? 134.052 144.865 156.551 1.00 79.13  ? 260 LEU   A C   1 
ATOM   1902 O O   . LEU   A 1 234 ? 133.559 143.970 155.838 1.00 80.58  ? 260 LEU   A O   1 
ATOM   1903 C CB  . LEU   A 1 234 ? 135.892 144.481 158.230 1.00 73.49  ? 260 LEU   A CB  1 
ATOM   1904 C CG  . LEU   A 1 234 ? 135.291 143.172 158.741 1.00 81.12  ? 260 LEU   A CG  1 
ATOM   1905 C CD1 . LEU   A 1 234 ? 135.563 142.040 157.773 1.00 83.73  ? 260 LEU   A CD1 1 
ATOM   1906 C CD2 . LEU   A 1 234 ? 135.852 142.845 160.113 1.00 76.36  ? 260 LEU   A CD2 1 
ATOM   1907 N N   . LEU   A 1 235 ? 133.305 145.809 157.128 1.00 77.04  ? 261 LEU   A N   1 
ATOM   1908 C CA  . LEU   A 1 235 ? 131.860 145.817 156.940 1.00 77.71  ? 261 LEU   A CA  1 
ATOM   1909 C C   . LEU   A 1 235 ? 131.501 146.019 155.476 1.00 79.47  ? 261 LEU   A C   1 
ATOM   1910 O O   . LEU   A 1 235 ? 130.552 145.407 154.978 1.00 83.65  ? 261 LEU   A O   1 
ATOM   1911 C CB  . LEU   A 1 235 ? 131.221 146.901 157.810 1.00 85.50  ? 261 LEU   A CB  1 
ATOM   1912 C CG  . LEU   A 1 235 ? 131.355 146.736 159.329 1.00 85.73  ? 261 LEU   A CG  1 
ATOM   1913 C CD1 . LEU   A 1 235 ? 130.774 147.947 160.046 1.00 83.72  ? 261 LEU   A CD1 1 
ATOM   1914 C CD2 . LEU   A 1 235 ? 130.693 145.457 159.822 1.00 80.45  ? 261 LEU   A CD2 1 
ATOM   1915 N N   . LEU   A 1 236 ? 132.248 146.867 154.765 1.00 79.68  ? 262 LEU   A N   1 
ATOM   1916 C CA  . LEU   A 1 236 ? 131.978 147.075 153.351 1.00 77.72  ? 262 LEU   A CA  1 
ATOM   1917 C C   . LEU   A 1 236 ? 132.314 145.842 152.532 1.00 79.57  ? 262 LEU   A C   1 
ATOM   1918 O O   . LEU   A 1 236 ? 131.644 145.576 151.535 1.00 83.69  ? 262 LEU   A O   1 
ATOM   1919 C CB  . LEU   A 1 236 ? 132.763 148.274 152.828 1.00 80.32  ? 262 LEU   A CB  1 
ATOM   1920 C CG  . LEU   A 1 236 ? 132.481 148.624 151.365 1.00 85.16  ? 262 LEU   A CG  1 
ATOM   1921 C CD1 . LEU   A 1 236 ? 132.288 150.122 151.205 1.00 90.57  ? 262 LEU   A CD1 1 
ATOM   1922 C CD2 . LEU   A 1 236 ? 133.594 148.134 150.448 1.00 89.03  ? 262 LEU   A CD2 1 
ATOM   1923 N N   . ASP   A 1 237 ? 133.340 145.084 152.922 1.00 76.23  ? 263 ASP   A N   1 
ATOM   1924 C CA  . ASP   A 1 237 ? 133.621 143.834 152.226 1.00 74.57  ? 263 ASP   A CA  1 
ATOM   1925 C C   . ASP   A 1 237 ? 132.436 142.884 152.331 1.00 81.28  ? 263 ASP   A C   1 
ATOM   1926 O O   . ASP   A 1 237 ? 131.934 142.378 151.317 1.00 86.81  ? 263 ASP   A O   1 
ATOM   1927 C CB  . ASP   A 1 237 ? 134.883 143.186 152.793 1.00 75.20  ? 263 ASP   A CB  1 
ATOM   1928 C CG  . ASP   A 1 237 ? 136.141 143.961 152.455 1.00 91.62  ? 263 ASP   A CG  1 
ATOM   1929 O OD1 . ASP   A 1 237 ? 136.042 144.975 151.733 1.00 95.34  ? 263 ASP   A OD1 1 
ATOM   1930 O OD2 . ASP   A 1 237 ? 137.230 143.555 152.911 1.00 95.93  ? 263 ASP   A OD2 1 
ATOM   1931 N N   . LEU   A 1 238 ? 131.944 142.668 153.553 1.00 80.84  ? 264 LEU   A N   1 
ATOM   1932 C CA  . LEU   A 1 238 ? 130.809 141.757 153.719 1.00 76.69  ? 264 LEU   A CA  1 
ATOM   1933 C C   . LEU   A 1 238 ? 129.553 142.294 153.027 1.00 73.35  ? 264 LEU   A C   1 
ATOM   1934 O O   . LEU   A 1 238 ? 128.813 141.539 152.374 1.00 68.59  ? 264 LEU   A O   1 
ATOM   1935 C CB  . LEU   A 1 238 ? 130.548 141.517 155.206 1.00 82.05  ? 264 LEU   A CB  1 
ATOM   1936 C CG  . LEU   A 1 238 ? 131.740 141.041 156.047 1.00 83.01  ? 264 LEU   A CG  1 
ATOM   1937 C CD1 . LEU   A 1 238 ? 131.315 140.840 157.492 1.00 79.30  ? 264 LEU   A CD1 1 
ATOM   1938 C CD2 . LEU   A 1 238 ? 132.350 139.764 155.493 1.00 79.00  ? 264 LEU   A CD2 1 
ATOM   1939 N N   . SER   A 1 239 ? 129.305 143.601 153.147 1.00 81.19  ? 265 SER   A N   1 
ATOM   1940 C CA  . SER   A 1 239 ? 128.121 144.201 152.544 1.00 83.95  ? 265 SER   A CA  1 
ATOM   1941 C C   . SER   A 1 239 ? 128.176 144.140 151.023 1.00 80.75  ? 265 SER   A C   1 
ATOM   1942 O O   . SER   A 1 239 ? 127.171 143.844 150.377 1.00 77.15  ? 265 SER   A O   1 
ATOM   1943 C CB  . SER   A 1 239 ? 127.974 145.647 153.017 1.00 86.99  ? 265 SER   A CB  1 
ATOM   1944 O OG  . SER   A 1 239 ? 128.849 146.507 152.309 1.00 88.44  ? 265 SER   A OG  1 
ATOM   1945 N N   . ALA   A 1 240 ? 129.331 144.430 150.426 1.00 78.36  ? 266 ALA   A N   1 
ATOM   1946 C CA  . ALA   A 1 240 ? 129.458 144.299 148.984 1.00 74.58  ? 266 ALA   A CA  1 
ATOM   1947 C C   . ALA   A 1 240 ? 129.305 142.851 148.556 1.00 73.19  ? 266 ALA   A C   1 
ATOM   1948 O O   . ALA   A 1 240 ? 128.826 142.579 147.450 1.00 75.49  ? 266 ALA   A O   1 
ATOM   1949 C CB  . ALA   A 1 240 ? 130.806 144.849 148.522 1.00 76.71  ? 266 ALA   A CB  1 
ATOM   1950 N N   . GLY   A 1 241 ? 129.708 141.910 149.411 1.00 74.41  ? 267 GLY   A N   1 
ATOM   1951 C CA  . GLY   A 1 241 ? 129.486 140.512 149.091 1.00 73.18  ? 267 GLY   A CA  1 
ATOM   1952 C C   . GLY   A 1 241 ? 128.013 140.166 148.992 1.00 68.86  ? 267 GLY   A C   1 
ATOM   1953 O O   . GLY   A 1 241 ? 127.581 139.510 148.041 1.00 59.28  ? 267 GLY   A O   1 
ATOM   1954 N N   . PHE   A 1 242 ? 127.217 140.623 149.964 1.00 72.86  ? 268 PHE   A N   1 
ATOM   1955 C CA  . PHE   A 1 242 ? 125.851 140.116 150.119 1.00 68.93  ? 268 PHE   A CA  1 
ATOM   1956 C C   . PHE   A 1 242 ? 124.752 141.033 149.583 1.00 66.56  ? 268 PHE   A C   1 
ATOM   1957 O O   . PHE   A 1 242 ? 123.762 140.533 149.044 1.00 66.68  ? 268 PHE   A O   1 
ATOM   1958 C CB  . PHE   A 1 242 ? 125.574 139.819 151.594 1.00 73.12  ? 268 PHE   A CB  1 
ATOM   1959 C CG  . PHE   A 1 242 ? 125.951 138.428 152.005 1.00 78.67  ? 268 PHE   A CG  1 
ATOM   1960 C CD1 . PHE   A 1 242 ? 127.262 138.112 152.311 1.00 81.53  ? 268 PHE   A CD1 1 
ATOM   1961 C CD2 . PHE   A 1 242 ? 124.993 137.433 152.082 1.00 80.21  ? 268 PHE   A CD2 1 
ATOM   1962 C CE1 . PHE   A 1 242 ? 127.611 136.831 152.689 1.00 85.54  ? 268 PHE   A CE1 1 
ATOM   1963 C CE2 . PHE   A 1 242 ? 125.336 136.150 152.459 1.00 86.57  ? 268 PHE   A CE2 1 
ATOM   1964 C CZ  . PHE   A 1 242 ? 126.647 135.849 152.763 1.00 88.42  ? 268 PHE   A CZ  1 
ATOM   1965 N N   . LEU   A 1 243 ? 124.877 142.355 149.728 1.00 70.10  ? 269 LEU   A N   1 
ATOM   1966 C CA  . LEU   A 1 243 ? 123.766 143.257 149.429 1.00 68.96  ? 269 LEU   A CA  1 
ATOM   1967 C C   . LEU   A 1 243 ? 123.378 143.228 147.956 1.00 72.99  ? 269 LEU   A C   1 
ATOM   1968 O O   . LEU   A 1 243 ? 122.187 143.245 147.624 1.00 75.61  ? 269 LEU   A O   1 
ATOM   1969 C CB  . LEU   A 1 243 ? 124.126 144.687 149.832 1.00 66.70  ? 269 LEU   A CB  1 
ATOM   1970 C CG  . LEU   A 1 243 ? 124.354 145.005 151.308 1.00 67.85  ? 269 LEU   A CG  1 
ATOM   1971 C CD1 . LEU   A 1 243 ? 124.742 146.464 151.439 1.00 70.59  ? 269 LEU   A CD1 1 
ATOM   1972 C CD2 . LEU   A 1 243 ? 123.121 144.703 152.145 1.00 73.39  ? 269 LEU   A CD2 1 
ATOM   1973 N N   . LEU   A 1 244 ? 124.366 143.203 147.057 1.00 67.86  ? 270 LEU   A N   1 
ATOM   1974 C CA  . LEU   A 1 244 ? 124.083 143.386 145.637 1.00 66.60  ? 270 LEU   A CA  1 
ATOM   1975 C C   . LEU   A 1 244 ? 123.195 142.280 145.081 1.00 69.04  ? 270 LEU   A C   1 
ATOM   1976 O O   . LEU   A 1 244 ? 122.429 142.518 144.141 1.00 71.50  ? 270 LEU   A O   1 
ATOM   1977 C CB  . LEU   A 1 244 ? 125.387 143.452 144.842 1.00 63.56  ? 270 LEU   A CB  1 
ATOM   1978 C CG  . LEU   A 1 244 ? 126.385 144.550 145.212 1.00 62.21  ? 270 LEU   A CG  1 
ATOM   1979 C CD1 . LEU   A 1 244 ? 127.637 144.428 144.365 1.00 63.91  ? 270 LEU   A CD1 1 
ATOM   1980 C CD2 . LEU   A 1 244 ? 125.773 145.926 145.051 1.00 67.65  ? 270 LEU   A CD2 1 
ATOM   1981 N N   . PHE   A 1 245 ? 123.285 141.071 145.637 1.00 63.59  ? 271 PHE   A N   1 
ATOM   1982 C CA  . PHE   A 1 245 ? 122.516 139.958 145.093 1.00 61.84  ? 271 PHE   A CA  1 
ATOM   1983 C C   . PHE   A 1 245 ? 121.018 140.166 145.285 1.00 70.91  ? 271 PHE   A C   1 
ATOM   1984 O O   . PHE   A 1 245 ? 120.225 139.847 144.392 1.00 77.35  ? 271 PHE   A O   1 
ATOM   1985 C CB  . PHE   A 1 245 ? 122.962 138.649 145.739 1.00 62.73  ? 271 PHE   A CB  1 
ATOM   1986 C CG  . PHE   A 1 245 ? 122.262 137.440 145.194 1.00 69.17  ? 271 PHE   A CG  1 
ATOM   1987 C CD1 . PHE   A 1 245 ? 122.494 137.017 143.900 1.00 76.15  ? 271 PHE   A CD1 1 
ATOM   1988 C CD2 . PHE   A 1 245 ? 121.379 136.722 145.978 1.00 72.45  ? 271 PHE   A CD2 1 
ATOM   1989 C CE1 . PHE   A 1 245 ? 121.853 135.905 143.396 1.00 78.65  ? 271 PHE   A CE1 1 
ATOM   1990 C CE2 . PHE   A 1 245 ? 120.737 135.609 145.480 1.00 76.94  ? 271 PHE   A CE2 1 
ATOM   1991 C CZ  . PHE   A 1 245 ? 120.974 135.200 144.189 1.00 78.43  ? 271 PHE   A CZ  1 
ATOM   1992 N N   . PHE   A 1 246 ? 120.613 140.704 146.431 1.00 71.32  ? 272 PHE   A N   1 
ATOM   1993 C CA  . PHE   A 1 246 ? 119.200 140.842 146.744 1.00 69.25  ? 272 PHE   A CA  1 
ATOM   1994 C C   . PHE   A 1 246 ? 118.616 142.091 146.086 1.00 73.38  ? 272 PHE   A C   1 
ATOM   1995 O O   . PHE   A 1 246 ? 119.326 143.041 145.749 1.00 74.84  ? 272 PHE   A O   1 
ATOM   1996 C CB  . PHE   A 1 246 ? 118.994 140.884 148.254 1.00 65.77  ? 272 PHE   A CB  1 
ATOM   1997 C CG  . PHE   A 1 246 ? 119.471 139.649 148.960 1.00 60.66  ? 272 PHE   A CG  1 
ATOM   1998 C CD1 . PHE   A 1 246 ? 118.711 138.496 148.954 1.00 59.08  ? 272 PHE   A CD1 1 
ATOM   1999 C CD2 . PHE   A 1 246 ? 120.679 139.642 149.630 1.00 66.96  ? 272 PHE   A CD2 1 
ATOM   2000 C CE1 . PHE   A 1 246 ? 119.145 137.362 149.602 1.00 61.10  ? 272 PHE   A CE1 1 
ATOM   2001 C CE2 . PHE   A 1 246 ? 121.118 138.508 150.280 1.00 72.34  ? 272 PHE   A CE2 1 
ATOM   2002 C CZ  . PHE   A 1 246 ? 120.350 137.366 150.265 1.00 66.92  ? 272 PHE   A CZ  1 
ATOM   2003 N N   . ASP   A 1 247 ? 117.293 142.073 145.907 1.00 72.55  ? 273 ASP   A N   1 
ATOM   2004 C CA  . ASP   A 1 247 ? 116.640 143.088 145.085 1.00 73.75  ? 273 ASP   A CA  1 
ATOM   2005 C C   . ASP   A 1 247 ? 116.599 144.444 145.778 1.00 68.27  ? 273 ASP   A C   1 
ATOM   2006 O O   . ASP   A 1 247 ? 116.886 145.472 145.156 1.00 67.42  ? 273 ASP   A O   1 
ATOM   2007 C CB  . ASP   A 1 247 ? 115.224 142.637 144.730 1.00 83.38  ? 273 ASP   A CB  1 
ATOM   2008 C CG  . ASP   A 1 247 ? 115.199 141.309 144.000 1.00 92.36  ? 273 ASP   A CG  1 
ATOM   2009 O OD1 . ASP   A 1 247 ? 116.111 141.062 143.185 1.00 90.56  ? 273 ASP   A OD1 1 
ATOM   2010 O OD2 . ASP   A 1 247 ? 114.268 140.513 144.242 1.00 90.08  ? 273 ASP   A OD2 1 
ATOM   2011 N N   . VAL   A 1 248 ? 116.234 144.469 147.060 1.00 72.23  ? 274 VAL   A N   1 
ATOM   2012 C CA  . VAL   A 1 248 ? 115.985 145.739 147.737 1.00 73.25  ? 274 VAL   A CA  1 
ATOM   2013 C C   . VAL   A 1 248 ? 117.280 146.519 147.929 1.00 74.50  ? 274 VAL   A C   1 
ATOM   2014 O O   . VAL   A 1 248 ? 117.291 147.753 147.857 1.00 75.74  ? 274 VAL   A O   1 
ATOM   2015 C CB  . VAL   A 1 248 ? 115.269 145.493 149.078 1.00 73.91  ? 274 VAL   A CB  1 
ATOM   2016 C CG1 . VAL   A 1 248 ? 115.053 146.811 149.814 1.00 71.62  ? 274 VAL   A CG1 1 
ATOM   2017 C CG2 . VAL   A 1 248 ? 113.943 144.770 148.853 1.00 74.51  ? 274 VAL   A CG2 1 
ATOM   2018 N N   . SER   A 1 249 ? 118.386 145.821 148.177 1.00 72.71  ? 275 SER   A N   1 
ATOM   2019 C CA  . SER   A 1 249 ? 119.626 146.437 148.632 1.00 71.01  ? 275 SER   A CA  1 
ATOM   2020 C C   . SER   A 1 249 ? 120.565 146.839 147.499 1.00 71.45  ? 275 SER   A C   1 
ATOM   2021 O O   . SER   A 1 249 ? 121.693 147.257 147.775 1.00 74.31  ? 275 SER   A O   1 
ATOM   2022 C CB  . SER   A 1 249 ? 120.358 145.485 149.579 1.00 73.50  ? 275 SER   A CB  1 
ATOM   2023 O OG  . SER   A 1 249 ? 119.550 145.154 150.694 1.00 72.53  ? 275 SER   A OG  1 
ATOM   2024 N N   . ARG   A 1 250 ? 120.143 146.716 146.240 1.00 72.49  ? 276 ARG   A N   1 
ATOM   2025 C CA  . ARG   A 1 250 ? 121.074 146.931 145.137 1.00 72.76  ? 276 ARG   A CA  1 
ATOM   2026 C C   . ARG   A 1 250 ? 121.534 148.382 145.053 1.00 71.68  ? 276 ARG   A C   1 
ATOM   2027 O O   . ARG   A 1 250 ? 122.713 148.645 144.794 1.00 79.48  ? 276 ARG   A O   1 
ATOM   2028 C CB  . ARG   A 1 250 ? 120.439 146.494 143.817 1.00 72.93  ? 276 ARG   A CB  1 
ATOM   2029 C CG  . ARG   A 1 250 ? 121.387 146.592 142.635 1.00 69.69  ? 276 ARG   A CG  1 
ATOM   2030 C CD  . ARG   A 1 250 ? 120.890 145.836 141.419 1.00 70.34  ? 276 ARG   A CD  1 
ATOM   2031 N NE  . ARG   A 1 250 ? 121.052 144.390 141.556 1.00 69.73  ? 276 ARG   A NE  1 
ATOM   2032 C CZ  . ARG   A 1 250 ? 120.110 143.531 141.926 1.00 70.12  ? 276 ARG   A CZ  1 
ATOM   2033 N NH1 . ARG   A 1 250 ? 118.883 143.922 142.234 1.00 71.80  ? 276 ARG   A NH1 1 
ATOM   2034 N NH2 . ARG   A 1 250 ? 120.405 142.236 141.986 1.00 70.56  ? 276 ARG   A NH2 1 
ATOM   2035 N N   . SER   A 1 251 ? 120.628 149.339 145.260 1.00 65.23  ? 277 SER   A N   1 
ATOM   2036 C CA  . SER   A 1 251 ? 120.985 150.744 145.075 1.00 76.14  ? 277 SER   A CA  1 
ATOM   2037 C C   . SER   A 1 251 ? 122.004 151.208 146.113 1.00 81.30  ? 277 SER   A C   1 
ATOM   2038 O O   . SER   A 1 251 ? 123.031 151.811 145.766 1.00 81.75  ? 277 SER   A O   1 
ATOM   2039 C CB  . SER   A 1 251 ? 119.728 151.611 145.140 1.00 75.56  ? 277 SER   A CB  1 
ATOM   2040 O OG  . SER   A 1 251 ? 119.077 151.468 146.390 1.00 83.66  ? 277 SER   A OG  1 
ATOM   2041 N N   . ILE   A 1 252 ? 121.728 150.950 147.393 1.00 79.70  ? 278 ILE   A N   1 
ATOM   2042 C CA  . ILE   A 1 252 ? 122.630 151.385 148.456 1.00 78.64  ? 278 ILE   A CA  1 
ATOM   2043 C C   . ILE   A 1 252 ? 123.979 150.696 148.315 1.00 82.64  ? 278 ILE   A C   1 
ATOM   2044 O O   . ILE   A 1 252 ? 125.037 151.319 148.484 1.00 87.99  ? 278 ILE   A O   1 
ATOM   2045 C CB  . ILE   A 1 252 ? 122.002 151.111 149.837 1.00 80.03  ? 278 ILE   A CB  1 
ATOM   2046 C CG1 . ILE   A 1 252 ? 120.646 151.819 149.992 1.00 84.53  ? 278 ILE   A CG1 1 
ATOM   2047 C CG2 . ILE   A 1 252 ? 122.960 151.520 150.947 1.00 81.82  ? 278 ILE   A CG2 1 
ATOM   2048 C CD1 . ILE   A 1 252 ? 120.678 153.338 149.846 1.00 85.07  ? 278 ILE   A CD1 1 
ATOM   2049 N N   . GLY   A 1 253 ? 123.961 149.395 148.018 1.00 79.90  ? 279 GLY   A N   1 
ATOM   2050 C CA  . GLY   A 1 253 ? 125.205 148.677 147.813 1.00 77.83  ? 279 GLY   A CA  1 
ATOM   2051 C C   . GLY   A 1 253 ? 126.009 149.232 146.656 1.00 70.73  ? 279 GLY   A C   1 
ATOM   2052 O O   . GLY   A 1 253 ? 127.228 149.378 146.751 1.00 77.30  ? 279 GLY   A O   1 
ATOM   2053 N N   . LEU   A 1 254 ? 125.339 149.549 145.546 1.00 68.36  ? 280 LEU   A N   1 
ATOM   2054 C CA  . LEU   A 1 254 ? 126.044 150.107 144.399 1.00 72.38  ? 280 LEU   A CA  1 
ATOM   2055 C C   . LEU   A 1 254 ? 126.668 151.449 144.743 1.00 78.46  ? 280 LEU   A C   1 
ATOM   2056 O O   . LEU   A 1 254 ? 127.823 151.710 144.388 1.00 85.54  ? 280 LEU   A O   1 
ATOM   2057 C CB  . LEU   A 1 254 ? 125.096 150.252 143.208 1.00 68.33  ? 280 LEU   A CB  1 
ATOM   2058 C CG  . LEU   A 1 254 ? 124.823 149.001 142.369 1.00 70.74  ? 280 LEU   A CG  1 
ATOM   2059 C CD1 . LEU   A 1 254 ? 123.682 149.258 141.406 1.00 69.28  ? 280 LEU   A CD1 1 
ATOM   2060 C CD2 . LEU   A 1 254 ? 126.063 148.563 141.608 1.00 70.55  ? 280 LEU   A CD2 1 
ATOM   2061 N N   . PHE   A 1 255 ? 125.927 152.307 145.448 1.00 76.18  ? 281 PHE   A N   1 
ATOM   2062 C CA  . PHE   A 1 255 ? 126.473 153.606 145.833 1.00 80.45  ? 281 PHE   A CA  1 
ATOM   2063 C C   . PHE   A 1 255 ? 127.698 153.446 146.730 1.00 83.24  ? 281 PHE   A C   1 
ATOM   2064 O O   . PHE   A 1 255 ? 128.749 154.058 146.484 1.00 83.11  ? 281 PHE   A O   1 
ATOM   2065 C CB  . PHE   A 1 255 ? 125.400 154.437 146.532 1.00 83.19  ? 281 PHE   A CB  1 
ATOM   2066 C CG  . PHE   A 1 255 ? 125.910 155.728 147.100 1.00 90.58  ? 281 PHE   A CG  1 
ATOM   2067 C CD1 . PHE   A 1 255 ? 126.147 156.816 146.277 1.00 93.02  ? 281 PHE   A CD1 1 
ATOM   2068 C CD2 . PHE   A 1 255 ? 126.152 155.856 148.456 1.00 87.28  ? 281 PHE   A CD2 1 
ATOM   2069 C CE1 . PHE   A 1 255 ? 126.617 158.006 146.798 1.00 93.05  ? 281 PHE   A CE1 1 
ATOM   2070 C CE2 . PHE   A 1 255 ? 126.622 157.041 148.983 1.00 90.92  ? 281 PHE   A CE2 1 
ATOM   2071 C CZ  . PHE   A 1 255 ? 126.855 158.118 148.153 1.00 94.46  ? 281 PHE   A CZ  1 
ATOM   2072 N N   . PHE   A 1 256 ? 127.584 152.612 147.771 1.00 79.97  ? 282 PHE   A N   1 
ATOM   2073 C CA  . PHE   A 1 256 ? 128.703 152.428 148.691 1.00 73.98  ? 282 PHE   A CA  1 
ATOM   2074 C C   . PHE   A 1 256 ? 129.914 151.838 147.983 1.00 77.30  ? 282 PHE   A C   1 
ATOM   2075 O O   . PHE   A 1 256 ? 131.038 152.314 148.172 1.00 81.38  ? 282 PHE   A O   1 
ATOM   2076 C CB  . PHE   A 1 256 ? 128.300 151.523 149.862 1.00 74.20  ? 282 PHE   A CB  1 
ATOM   2077 C CG  . PHE   A 1 256 ? 127.319 152.139 150.847 1.00 84.44  ? 282 PHE   A CG  1 
ATOM   2078 C CD1 . PHE   A 1 256 ? 127.049 153.503 150.880 1.00 89.15  ? 282 PHE   A CD1 1 
ATOM   2079 C CD2 . PHE   A 1 256 ? 126.676 151.324 151.766 1.00 95.65  ? 282 PHE   A CD2 1 
ATOM   2080 C CE1 . PHE   A 1 256 ? 126.156 154.028 151.795 1.00 100.42 ? 282 PHE   A CE1 1 
ATOM   2081 C CE2 . PHE   A 1 256 ? 125.785 151.848 152.682 1.00 99.05  ? 282 PHE   A CE2 1 
ATOM   2082 C CZ  . PHE   A 1 256 ? 125.525 153.199 152.696 1.00 103.13 ? 282 PHE   A CZ  1 
ATOM   2083 N N   . VAL   A 1 257 ? 129.711 150.814 147.153 1.00 77.50  ? 283 VAL   A N   1 
ATOM   2084 C CA  . VAL   A 1 257 ? 130.844 150.161 146.509 1.00 74.58  ? 283 VAL   A CA  1 
ATOM   2085 C C   . VAL   A 1 257 ? 131.489 151.088 145.487 1.00 76.59  ? 283 VAL   A C   1 
ATOM   2086 O O   . VAL   A 1 257 ? 132.717 151.119 145.353 1.00 84.44  ? 283 VAL   A O   1 
ATOM   2087 C CB  . VAL   A 1 257 ? 130.402 148.828 145.879 1.00 73.02  ? 283 VAL   A CB  1 
ATOM   2088 C CG1 . VAL   A 1 257 ? 131.517 148.236 145.041 1.00 73.00  ? 283 VAL   A CG1 1 
ATOM   2089 C CG2 . VAL   A 1 257 ? 129.995 147.843 146.963 1.00 74.95  ? 283 VAL   A CG2 1 
ATOM   2090 N N   . SER   A 1 258 ? 130.686 151.870 144.761 1.00 70.18  ? 284 SER   A N   1 
ATOM   2091 C CA  . SER   A 1 258 ? 131.250 152.793 143.783 1.00 76.08  ? 284 SER   A CA  1 
ATOM   2092 C C   . SER   A 1 258 ? 132.083 153.872 144.464 1.00 83.85  ? 284 SER   A C   1 
ATOM   2093 O O   . SER   A 1 258 ? 133.206 154.169 144.033 1.00 86.40  ? 284 SER   A O   1 
ATOM   2094 C CB  . SER   A 1 258 ? 130.132 153.419 142.951 1.00 75.40  ? 284 SER   A CB  1 
ATOM   2095 O OG  . SER   A 1 258 ? 129.379 152.423 142.281 1.00 77.87  ? 284 SER   A OG  1 
ATOM   2096 N N   . TYR   A 1 259 ? 131.552 154.472 145.534 1.00 83.15  ? 285 TYR   A N   1 
ATOM   2097 C CA  . TYR   A 1 259 ? 132.315 155.492 146.246 1.00 83.38  ? 285 TYR   A CA  1 
ATOM   2098 C C   . TYR   A 1 259 ? 133.572 154.898 146.871 1.00 80.71  ? 285 TYR   A C   1 
ATOM   2099 O O   . TYR   A 1 259 ? 134.646 155.514 146.833 1.00 87.24  ? 285 TYR   A O   1 
ATOM   2100 C CB  . TYR   A 1 259 ? 131.442 156.151 147.310 1.00 85.31  ? 285 TYR   A CB  1 
ATOM   2101 C CG  . TYR   A 1 259 ? 132.216 156.971 148.312 1.00 86.46  ? 285 TYR   A CG  1 
ATOM   2102 C CD1 . TYR   A 1 259 ? 132.868 158.136 147.932 1.00 91.31  ? 285 TYR   A CD1 1 
ATOM   2103 C CD2 . TYR   A 1 259 ? 132.287 156.586 149.640 1.00 85.48  ? 285 TYR   A CD2 1 
ATOM   2104 C CE1 . TYR   A 1 259 ? 133.576 158.889 148.849 1.00 96.66  ? 285 TYR   A CE1 1 
ATOM   2105 C CE2 . TYR   A 1 259 ? 132.988 157.331 150.562 1.00 95.77  ? 285 TYR   A CE2 1 
ATOM   2106 C CZ  . TYR   A 1 259 ? 133.632 158.481 150.164 1.00 100.10 ? 285 TYR   A CZ  1 
ATOM   2107 O OH  . TYR   A 1 259 ? 134.333 159.224 151.086 1.00 102.13 ? 285 TYR   A OH  1 
ATOM   2108 N N   . PHE   A 1 260 ? 133.455 153.698 147.443 1.00 73.73  ? 286 PHE   A N   1 
ATOM   2109 C CA  . PHE   A 1 260 ? 134.607 153.007 148.007 1.00 79.97  ? 286 PHE   A CA  1 
ATOM   2110 C C   . PHE   A 1 260 ? 135.689 152.785 146.960 1.00 78.96  ? 286 PHE   A C   1 
ATOM   2111 O O   . PHE   A 1 260 ? 136.874 153.018 147.224 1.00 83.65  ? 286 PHE   A O   1 
ATOM   2112 C CB  . PHE   A 1 260 ? 134.143 151.681 148.611 1.00 85.69  ? 286 PHE   A CB  1 
ATOM   2113 C CG  . PHE   A 1 260 ? 135.249 150.710 148.907 1.00 84.63  ? 286 PHE   A CG  1 
ATOM   2114 C CD1 . PHE   A 1 260 ? 136.012 150.834 150.052 1.00 87.41  ? 286 PHE   A CD1 1 
ATOM   2115 C CD2 . PHE   A 1 260 ? 135.500 149.649 148.057 1.00 82.61  ? 286 PHE   A CD2 1 
ATOM   2116 C CE1 . PHE   A 1 260 ? 137.016 149.933 150.329 1.00 88.64  ? 286 PHE   A CE1 1 
ATOM   2117 C CE2 . PHE   A 1 260 ? 136.503 148.748 148.332 1.00 84.73  ? 286 PHE   A CE2 1 
ATOM   2118 C CZ  . PHE   A 1 260 ? 137.259 148.889 149.470 1.00 86.91  ? 286 PHE   A CZ  1 
ATOM   2119 N N   . HIS   A 1 261 ? 135.305 152.346 145.760 1.00 76.11  ? 287 HIS   A N   1 
ATOM   2120 C CA  . HIS   A 1 261 ? 136.304 152.045 144.743 1.00 75.94  ? 287 HIS   A CA  1 
ATOM   2121 C C   . HIS   A 1 261 ? 136.936 153.315 144.192 1.00 80.15  ? 287 HIS   A C   1 
ATOM   2122 O O   . HIS   A 1 261 ? 138.138 153.337 143.910 1.00 88.25  ? 287 HIS   A O   1 
ATOM   2123 C CB  . HIS   A 1 261 ? 135.681 151.219 143.620 1.00 73.05  ? 287 HIS   A CB  1 
ATOM   2124 C CG  . HIS   A 1 261 ? 135.532 149.767 143.952 1.00 70.03  ? 287 HIS   A CG  1 
ATOM   2125 N ND1 . HIS   A 1 261 ? 136.514 149.042 144.591 1.00 68.87  ? 287 HIS   A ND1 1 
ATOM   2126 C CD2 . HIS   A 1 261 ? 134.514 148.904 143.730 1.00 75.15  ? 287 HIS   A CD2 1 
ATOM   2127 C CE1 . HIS   A 1 261 ? 136.106 147.797 144.751 1.00 77.14  ? 287 HIS   A CE1 1 
ATOM   2128 N NE2 . HIS   A 1 261 ? 134.895 147.687 144.239 1.00 78.80  ? 287 HIS   A NE2 1 
ATOM   2129 N N   . CYS   A 1 262 ? 136.154 154.385 144.036 1.00 79.37  ? 288 CYS   A N   1 
ATOM   2130 C CA  . CYS   A 1 262 ? 136.746 155.650 143.607 1.00 83.27  ? 288 CYS   A CA  1 
ATOM   2131 C C   . CYS   A 1 262 ? 137.742 156.167 144.640 1.00 86.24  ? 288 CYS   A C   1 
ATOM   2132 O O   . CYS   A 1 262 ? 138.844 156.618 144.291 1.00 89.37  ? 288 CYS   A O   1 
ATOM   2133 C CB  . CYS   A 1 262 ? 135.650 156.683 143.353 1.00 85.81  ? 288 CYS   A CB  1 
ATOM   2134 S SG  . CYS   A 1 262 ? 134.656 156.366 141.879 1.00 97.07  ? 288 CYS   A SG  1 
ATOM   2135 N N   . MET   A 1 263 ? 137.378 156.092 145.923 1.00 82.90  ? 289 MET   A N   1 
ATOM   2136 C CA  . MET   A 1 263 ? 138.281 156.549 146.972 1.00 81.30  ? 289 MET   A CA  1 
ATOM   2137 C C   . MET   A 1 263 ? 139.541 155.695 147.020 1.00 82.67  ? 289 MET   A C   1 
ATOM   2138 O O   . MET   A 1 263 ? 140.643 156.219 147.209 1.00 89.67  ? 289 MET   A O   1 
ATOM   2139 C CB  . MET   A 1 263 ? 137.564 156.532 148.321 1.00 85.13  ? 289 MET   A CB  1 
ATOM   2140 C CG  . MET   A 1 263 ? 138.154 157.480 149.348 1.00 91.76  ? 289 MET   A CG  1 
ATOM   2141 S SD  . MET   A 1 263 ? 137.206 157.504 150.881 1.00 115.07 ? 289 MET   A SD  1 
ATOM   2142 C CE  . MET   A 1 263 ? 138.071 158.775 151.800 1.00 103.94 ? 289 MET   A CE  1 
ATOM   2143 N N   . ASN   A 1 264 ? 139.401 154.377 146.856 1.00 80.55  ? 290 ASN   A N   1 
ATOM   2144 C CA  . ASN   A 1 264 ? 140.575 153.509 146.813 1.00 81.01  ? 290 ASN   A CA  1 
ATOM   2145 C C   . ASN   A 1 264 ? 141.463 153.835 145.619 1.00 83.08  ? 290 ASN   A C   1 
ATOM   2146 O O   . ASN   A 1 264 ? 142.694 153.832 145.736 1.00 89.43  ? 290 ASN   A O   1 
ATOM   2147 C CB  . ASN   A 1 264 ? 140.146 152.044 146.767 1.00 82.07  ? 290 ASN   A CB  1 
ATOM   2148 C CG  . ASN   A 1 264 ? 139.834 151.487 148.134 1.00 90.77  ? 290 ASN   A CG  1 
ATOM   2149 O OD1 . ASN   A 1 264 ? 139.522 152.229 149.066 1.00 95.25  ? 290 ASN   A OD1 1 
ATOM   2150 N ND2 . ASN   A 1 264 ? 139.921 150.171 148.267 1.00 92.79  ? 290 ASN   A ND2 1 
ATOM   2151 N N   . SER   A 1 265 ? 140.859 154.102 144.459 1.00 80.53  ? 291 SER   A N   1 
ATOM   2152 C CA  . SER   A 1 265 ? 141.647 154.420 143.274 1.00 81.20  ? 291 SER   A CA  1 
ATOM   2153 C C   . SER   A 1 265 ? 142.447 155.696 143.474 1.00 85.62  ? 291 SER   A C   1 
ATOM   2154 O O   . SER   A 1 265 ? 143.619 155.769 143.090 1.00 89.18  ? 291 SER   A O   1 
ATOM   2155 C CB  . SER   A 1 265 ? 140.734 154.559 142.058 1.00 84.43  ? 291 SER   A CB  1 
ATOM   2156 O OG  . SER   A 1 265 ? 141.479 154.892 140.900 1.00 91.13  ? 291 SER   A OG  1 
ATOM   2157 N N   . GLN   A 1 266 ? 141.834 156.713 144.081 1.00 89.76  ? 292 GLN   A N   1 
ATOM   2158 C CA  . GLN   A 1 266 ? 142.551 157.969 144.279 1.00 88.32  ? 292 GLN   A CA  1 
ATOM   2159 C C   . GLN   A 1 266 ? 143.556 157.888 145.424 1.00 87.91  ? 292 GLN   A C   1 
ATOM   2160 O O   . GLN   A 1 266 ? 144.586 158.569 145.381 1.00 92.77  ? 292 GLN   A O   1 
ATOM   2161 C CB  . GLN   A 1 266 ? 141.563 159.111 144.522 1.00 89.84  ? 292 GLN   A CB  1 
ATOM   2162 C CG  . GLN   A 1 266 ? 140.586 159.351 143.375 1.00 90.70  ? 292 GLN   A CG  1 
ATOM   2163 C CD  . GLN   A 1 266 ? 141.282 159.689 142.069 1.00 92.02  ? 292 GLN   A CD  1 
ATOM   2164 O OE1 . GLN   A 1 266 ? 142.425 160.142 142.063 1.00 85.73  ? 292 GLN   A OE1 1 
ATOM   2165 N NE2 . GLN   A 1 266 ? 140.596 159.459 140.956 1.00 92.49  ? 292 GLN   A NE2 1 
ATOM   2166 N N   . LEU   A 1 267 ? 143.286 157.075 146.447 1.00 86.27  ? 293 LEU   A N   1 
ATOM   2167 C CA  . LEU   A 1 267 ? 144.206 156.966 147.574 1.00 86.03  ? 293 LEU   A CA  1 
ATOM   2168 C C   . LEU   A 1 267 ? 145.449 156.158 147.220 1.00 88.06  ? 293 LEU   A C   1 
ATOM   2169 O O   . LEU   A 1 267 ? 146.561 156.529 147.609 1.00 93.39  ? 293 LEU   A O   1 
ATOM   2170 C CB  . LEU   A 1 267 ? 143.500 156.329 148.770 1.00 89.84  ? 293 LEU   A CB  1 
ATOM   2171 C CG  . LEU   A 1 267 ? 142.488 157.183 149.535 1.00 96.40  ? 293 LEU   A CG  1 
ATOM   2172 C CD1 . LEU   A 1 267 ? 141.683 156.315 150.489 1.00 95.81  ? 293 LEU   A CD1 1 
ATOM   2173 C CD2 . LEU   A 1 267 ? 143.184 158.297 150.296 1.00 94.63  ? 293 LEU   A CD2 1 
ATOM   2174 N N   . PHE   A 1 268 ? 145.281 155.062 146.487 1.00 83.93  ? 294 PHE   A N   1 
ATOM   2175 C CA  . PHE   A 1 268 ? 146.349 154.120 146.184 1.00 84.21  ? 294 PHE   A CA  1 
ATOM   2176 C C   . PHE   A 1 268 ? 146.774 154.261 144.725 1.00 94.08  ? 294 PHE   A C   1 
ATOM   2177 O O   . PHE   A 1 268 ? 146.194 155.029 143.954 1.00 93.69  ? 294 PHE   A O   1 
ATOM   2178 C CB  . PHE   A 1 268 ? 145.894 152.688 146.477 1.00 83.59  ? 294 PHE   A CB  1 
ATOM   2179 C CG  . PHE   A 1 268 ? 145.612 152.423 147.925 1.00 89.04  ? 294 PHE   A CG  1 
ATOM   2180 C CD1 . PHE   A 1 268 ? 144.401 152.781 148.488 1.00 96.25  ? 294 PHE   A CD1 1 
ATOM   2181 C CD2 . PHE   A 1 268 ? 146.554 151.800 148.720 1.00 92.59  ? 294 PHE   A CD2 1 
ATOM   2182 C CE1 . PHE   A 1 268 ? 144.140 152.534 149.818 1.00 98.64  ? 294 PHE   A CE1 1 
ATOM   2183 C CE2 . PHE   A 1 268 ? 146.299 151.548 150.050 1.00 97.58  ? 294 PHE   A CE2 1 
ATOM   2184 C CZ  . PHE   A 1 268 ? 145.090 151.916 150.600 1.00 98.75  ? 294 PHE   A CZ  1 
ATOM   2185 N N   . SER   A 1 269 ? 147.804 153.499 144.357 1.00 95.66  ? 295 SER   A N   1 
ATOM   2186 C CA  . SER   A 1 269 ? 148.288 153.375 142.988 1.00 86.82  ? 295 SER   A CA  1 
ATOM   2187 C C   . SER   A 1 269 ? 148.229 151.922 142.539 1.00 85.56  ? 295 SER   A C   1 
ATOM   2188 O O   . SER   A 1 269 ? 149.160 151.402 141.921 1.00 84.92  ? 295 SER   A O   1 
ATOM   2189 C CB  . SER   A 1 269 ? 149.708 153.919 142.857 1.00 87.08  ? 295 SER   A CB  1 
ATOM   2190 O OG  . SER   A 1 269 ? 150.615 153.169 143.645 1.00 97.71  ? 295 SER   A OG  1 
ATOM   2191 N N   . ILE   A 1 270 ? 147.124 151.248 142.863 1.00 86.23  ? 296 ILE   A N   1 
ATOM   2192 C CA  . ILE   A 1 270 ? 146.987 149.833 142.532 1.00 87.38  ? 296 ILE   A CA  1 
ATOM   2193 C C   . ILE   A 1 270 ? 146.966 149.635 141.021 1.00 92.03  ? 296 ILE   A C   1 
ATOM   2194 O O   . ILE   A 1 270 ? 147.482 148.634 140.509 1.00 92.62  ? 296 ILE   A O   1 
ATOM   2195 C CB  . ILE   A 1 270 ? 145.732 149.244 143.207 1.00 85.07  ? 296 ILE   A CB  1 
ATOM   2196 C CG1 . ILE   A 1 270 ? 144.447 149.923 142.707 1.00 84.57  ? 296 ILE   A CG1 1 
ATOM   2197 C CG2 . ILE   A 1 270 ? 145.844 149.370 144.720 1.00 90.73  ? 296 ILE   A CG2 1 
ATOM   2198 C CD1 . ILE   A 1 270 ? 143.198 149.480 143.441 1.00 88.92  ? 296 ILE   A CD1 1 
ATOM   2199 N N   . GLY   A 1 271 ? 146.371 150.577 140.290 1.00 89.40  ? 297 GLY   A N   1 
ATOM   2200 C CA  . GLY   A 1 271 ? 146.331 150.541 138.840 1.00 83.18  ? 297 GLY   A CA  1 
ATOM   2201 C C   . GLY   A 1 271 ? 144.920 150.480 138.297 1.00 89.94  ? 297 GLY   A C   1 
ATOM   2202 O O   . GLY   A 1 271 ? 144.114 151.382 138.543 1.00 96.45  ? 297 GLY   A O   1 
ATOM   2203 N N   . MET   A 1 272 ? 144.611 149.415 137.559 1.00 85.21  ? 298 MET   A N   1 
ATOM   2204 C CA  . MET   A 1 272 ? 143.309 149.235 136.932 1.00 80.10  ? 298 MET   A CA  1 
ATOM   2205 C C   . MET   A 1 272 ? 142.372 148.359 137.754 1.00 78.81  ? 298 MET   A C   1 
ATOM   2206 O O   . MET   A 1 272 ? 141.278 148.035 137.283 1.00 86.24  ? 298 MET   A O   1 
ATOM   2207 C CB  . MET   A 1 272 ? 143.481 148.627 135.539 1.00 80.19  ? 298 MET   A CB  1 
ATOM   2208 C CG  . MET   A 1 272 ? 144.279 149.476 134.567 1.00 85.03  ? 298 MET   A CG  1 
ATOM   2209 S SD  . MET   A 1 272 ? 143.431 150.985 134.071 1.00 97.74  ? 298 MET   A SD  1 
ATOM   2210 C CE  . MET   A 1 272 ? 144.515 151.553 132.764 1.00 93.37  ? 298 MET   A CE  1 
ATOM   2211 N N   . PHE   A 1 273 ? 142.768 147.970 138.968 1.00 73.87  ? 299 PHE   A N   1 
ATOM   2212 C CA  . PHE   A 1 273 ? 141.946 147.062 139.761 1.00 75.71  ? 299 PHE   A CA  1 
ATOM   2213 C C   . PHE   A 1 273 ? 140.623 147.713 140.142 1.00 79.38  ? 299 PHE   A C   1 
ATOM   2214 O O   . PHE   A 1 273 ? 139.555 147.100 140.013 1.00 85.89  ? 299 PHE   A O   1 
ATOM   2215 C CB  . PHE   A 1 273 ? 142.722 146.630 141.008 1.00 77.87  ? 299 PHE   A CB  1 
ATOM   2216 C CG  . PHE   A 1 273 ? 141.979 145.674 141.914 1.00 76.19  ? 299 PHE   A CG  1 
ATOM   2217 C CD1 . PHE   A 1 273 ? 141.083 144.741 141.415 1.00 78.26  ? 299 PHE   A CD1 1 
ATOM   2218 C CD2 . PHE   A 1 273 ? 142.205 145.702 143.277 1.00 81.85  ? 299 PHE   A CD2 1 
ATOM   2219 C CE1 . PHE   A 1 273 ? 140.423 143.876 142.259 1.00 86.95  ? 299 PHE   A CE1 1 
ATOM   2220 C CE2 . PHE   A 1 273 ? 141.548 144.838 144.122 1.00 87.36  ? 299 PHE   A CE2 1 
ATOM   2221 C CZ  . PHE   A 1 273 ? 140.657 143.924 143.614 1.00 92.45  ? 299 PHE   A CZ  1 
ATOM   2222 N N   . SER   A 1 274 ? 140.676 148.958 140.616 1.00 75.09  ? 300 SER   A N   1 
ATOM   2223 C CA  . SER   A 1 274 ? 139.459 149.630 141.055 1.00 77.58  ? 300 SER   A CA  1 
ATOM   2224 C C   . SER   A 1 274 ? 138.484 149.816 139.901 1.00 80.23  ? 300 SER   A C   1 
ATOM   2225 O O   . SER   A 1 274 ? 137.273 149.631 140.064 1.00 83.85  ? 300 SER   A O   1 
ATOM   2226 C CB  . SER   A 1 274 ? 139.806 150.975 141.686 1.00 79.68  ? 300 SER   A CB  1 
ATOM   2227 O OG  . SER   A 1 274 ? 138.640 151.628 142.153 1.00 85.57  ? 300 SER   A OG  1 
ATOM   2228 N N   . TYR   A 1 275 ? 138.993 150.173 138.723 1.00 78.18  ? 301 TYR   A N   1 
ATOM   2229 C CA  . TYR   A 1 275 ? 138.119 150.351 137.569 1.00 78.00  ? 301 TYR   A CA  1 
ATOM   2230 C C   . TYR   A 1 275 ? 137.502 149.027 137.132 1.00 74.36  ? 301 TYR   A C   1 
ATOM   2231 O O   . TYR   A 1 275 ? 136.331 148.983 136.738 1.00 81.60  ? 301 TYR   A O   1 
ATOM   2232 C CB  . TYR   A 1 275 ? 138.895 150.997 136.424 1.00 85.17  ? 301 TYR   A CB  1 
ATOM   2233 C CG  . TYR   A 1 275 ? 139.518 152.323 136.799 1.00 90.93  ? 301 TYR   A CG  1 
ATOM   2234 C CD1 . TYR   A 1 275 ? 138.760 153.482 136.834 1.00 91.60  ? 301 TYR   A CD1 1 
ATOM   2235 C CD2 . TYR   A 1 275 ? 140.862 152.412 137.121 1.00 90.97  ? 301 TYR   A CD2 1 
ATOM   2236 C CE1 . TYR   A 1 275 ? 139.323 154.692 137.177 1.00 94.34  ? 301 TYR   A CE1 1 
ATOM   2237 C CE2 . TYR   A 1 275 ? 141.434 153.617 137.464 1.00 93.33  ? 301 TYR   A CE2 1 
ATOM   2238 C CZ  . TYR   A 1 275 ? 140.661 154.754 137.491 1.00 96.70  ? 301 TYR   A CZ  1 
ATOM   2239 O OH  . TYR   A 1 275 ? 141.229 155.959 137.833 1.00 99.89  ? 301 TYR   A OH  1 
ATOM   2240 N N   . VAL   A 1 276 ? 138.268 147.937 137.193 1.00 68.09  ? 302 VAL   A N   1 
ATOM   2241 C CA  . VAL   A 1 276 ? 137.716 146.634 136.838 1.00 71.13  ? 302 VAL   A CA  1 
ATOM   2242 C C   . VAL   A 1 276 ? 136.630 146.227 137.828 1.00 75.97  ? 302 VAL   A C   1 
ATOM   2243 O O   . VAL   A 1 276 ? 135.605 145.653 137.441 1.00 80.12  ? 302 VAL   A O   1 
ATOM   2244 C CB  . VAL   A 1 276 ? 138.835 145.580 136.751 1.00 76.33  ? 302 VAL   A CB  1 
ATOM   2245 C CG1 . VAL   A 1 276 ? 138.252 144.181 136.642 1.00 75.92  ? 302 VAL   A CG1 1 
ATOM   2246 C CG2 . VAL   A 1 276 ? 139.730 145.854 135.553 1.00 79.84  ? 302 VAL   A CG2 1 
ATOM   2247 N N   . MET   A 1 277 ? 136.828 146.509 139.117 1.00 73.63  ? 303 MET   A N   1 
ATOM   2248 C CA  . MET   A 1 277 ? 135.785 146.195 140.091 1.00 75.00  ? 303 MET   A CA  1 
ATOM   2249 C C   . MET   A 1 277 ? 134.550 147.063 139.873 1.00 75.69  ? 303 MET   A C   1 
ATOM   2250 O O   . MET   A 1 277 ? 133.415 146.596 140.045 1.00 77.47  ? 303 MET   A O   1 
ATOM   2251 C CB  . MET   A 1 277 ? 136.318 146.361 141.514 1.00 76.37  ? 303 MET   A CB  1 
ATOM   2252 C CG  . MET   A 1 277 ? 137.422 145.380 141.899 1.00 78.68  ? 303 MET   A CG  1 
ATOM   2253 S SD  . MET   A 1 277 ? 136.942 143.641 141.863 1.00 83.93  ? 303 MET   A SD  1 
ATOM   2254 C CE  . MET   A 1 277 ? 135.669 143.600 143.120 1.00 83.16  ? 303 MET   A CE  1 
ATOM   2255 N N   . LEU   A 1 278 ? 134.747 148.328 139.495 1.00 72.65  ? 304 LEU   A N   1 
ATOM   2256 C CA  . LEU   A 1 278 ? 133.615 149.174 139.132 1.00 69.33  ? 304 LEU   A CA  1 
ATOM   2257 C C   . LEU   A 1 278 ? 132.862 148.591 137.943 1.00 75.52  ? 304 LEU   A C   1 
ATOM   2258 O O   . LEU   A 1 278 ? 131.630 148.633 137.898 1.00 78.77  ? 304 LEU   A O   1 
ATOM   2259 C CB  . LEU   A 1 278 ? 134.091 150.591 138.809 1.00 70.92  ? 304 LEU   A CB  1 
ATOM   2260 C CG  . LEU   A 1 278 ? 134.531 151.497 139.960 1.00 73.89  ? 304 LEU   A CG  1 
ATOM   2261 C CD1 . LEU   A 1 278 ? 135.081 152.799 139.412 1.00 80.02  ? 304 LEU   A CD1 1 
ATOM   2262 C CD2 . LEU   A 1 278 ? 133.383 151.770 140.910 1.00 74.57  ? 304 LEU   A CD2 1 
ATOM   2263 N N   . ALA   A 1 279 ? 133.593 148.062 136.961 1.00 75.91  ? 305 ALA   A N   1 
ATOM   2264 C CA  . ALA   A 1 279 ? 132.953 147.423 135.815 1.00 72.82  ? 305 ALA   A CA  1 
ATOM   2265 C C   . ALA   A 1 279 ? 132.193 146.170 136.231 1.00 69.12  ? 305 ALA   A C   1 
ATOM   2266 O O   . ALA   A 1 279 ? 131.146 145.850 135.658 1.00 69.61  ? 305 ALA   A O   1 
ATOM   2267 C CB  . ALA   A 1 279 ? 133.999 147.084 134.754 1.00 74.56  ? 305 ALA   A CB  1 
ATOM   2268 N N   . SER   A 1 280 ? 132.726 145.426 137.202 1.00 65.94  ? 306 SER   A N   1 
ATOM   2269 C CA  . SER   A 1 280 ? 132.072 144.199 137.646 1.00 70.01  ? 306 SER   A CA  1 
ATOM   2270 C C   . SER   A 1 280 ? 130.846 144.465 138.511 1.00 71.87  ? 306 SER   A C   1 
ATOM   2271 O O   . SER   A 1 280 ? 129.962 143.605 138.583 1.00 75.50  ? 306 SER   A O   1 
ATOM   2272 C CB  . SER   A 1 280 ? 133.059 143.328 138.422 1.00 73.31  ? 306 SER   A CB  1 
ATOM   2273 O OG  . SER   A 1 280 ? 133.298 143.857 139.715 1.00 80.37  ? 306 SER   A OG  1 
ATOM   2274 N N   . SER   A 1 281 ? 130.785 145.617 139.180 1.00 70.97  ? 307 SER   A N   1 
ATOM   2275 C CA  . SER   A 1 281 ? 129.661 145.898 140.074 1.00 68.05  ? 307 SER   A CA  1 
ATOM   2276 C C   . SER   A 1 281 ? 128.304 145.877 139.375 1.00 68.25  ? 307 SER   A C   1 
ATOM   2277 O O   . SER   A 1 281 ? 127.355 145.310 139.944 1.00 70.78  ? 307 SER   A O   1 
ATOM   2278 C CB  . SER   A 1 281 ? 129.899 147.233 140.788 1.00 73.94  ? 307 SER   A CB  1 
ATOM   2279 O OG  . SER   A 1 281 ? 130.725 147.058 141.925 1.00 83.51  ? 307 SER   A OG  1 
ATOM   2280 N N   . PRO   A 1 282 ? 128.125 146.459 138.183 1.00 65.64  ? 308 PRO   A N   1 
ATOM   2281 C CA  . PRO   A 1 282 ? 126.823 146.352 137.501 1.00 58.71  ? 308 PRO   A CA  1 
ATOM   2282 C C   . PRO   A 1 282 ? 126.411 144.938 137.137 1.00 61.61  ? 308 PRO   A C   1 
ATOM   2283 O O   . PRO   A 1 282 ? 125.235 144.733 136.812 1.00 70.15  ? 308 PRO   A O   1 
ATOM   2284 C CB  . PRO   A 1 282 ? 127.019 147.192 136.236 1.00 56.41  ? 308 PRO   A CB  1 
ATOM   2285 C CG  . PRO   A 1 282 ? 128.033 148.180 136.595 1.00 68.32  ? 308 PRO   A CG  1 
ATOM   2286 C CD  . PRO   A 1 282 ? 128.944 147.535 137.599 1.00 72.06  ? 308 PRO   A CD  1 
ATOM   2287 N N   . LEU   A 1 283 ? 127.323 143.964 137.159 1.00 64.92  ? 309 LEU   A N   1 
ATOM   2288 C CA  . LEU   A 1 283 ? 126.988 142.623 136.694 1.00 66.68  ? 309 LEU   A CA  1 
ATOM   2289 C C   . LEU   A 1 283 ? 125.902 141.965 137.536 1.00 64.88  ? 309 LEU   A C   1 
ATOM   2290 O O   . LEU   A 1 283 ? 125.243 141.036 137.057 1.00 63.78  ? 309 LEU   A O   1 
ATOM   2291 C CB  . LEU   A 1 283 ? 128.242 141.746 136.682 1.00 67.10  ? 309 LEU   A CB  1 
ATOM   2292 C CG  . LEU   A 1 283 ? 128.266 140.608 135.657 1.00 67.36  ? 309 LEU   A CG  1 
ATOM   2293 C CD1 . LEU   A 1 283 ? 128.365 141.142 134.237 1.00 62.72  ? 309 LEU   A CD1 1 
ATOM   2294 C CD2 . LEU   A 1 283 ? 129.411 139.657 135.932 1.00 70.09  ? 309 LEU   A CD2 1 
ATOM   2295 N N   . PHE   A 1 284 ? 125.696 142.421 138.773 1.00 65.02  ? 310 PHE   A N   1 
ATOM   2296 C CA  . PHE   A 1 284 ? 124.613 141.914 139.605 1.00 69.50  ? 310 PHE   A CA  1 
ATOM   2297 C C   . PHE   A 1 284 ? 123.249 142.473 139.218 1.00 70.31  ? 310 PHE   A C   1 
ATOM   2298 O O   . PHE   A 1 284 ? 122.237 142.002 139.745 1.00 71.86  ? 310 PHE   A O   1 
ATOM   2299 C CB  . PHE   A 1 284 ? 124.888 142.231 141.076 1.00 69.75  ? 310 PHE   A CB  1 
ATOM   2300 C CG  . PHE   A 1 284 ? 126.034 141.458 141.657 1.00 65.04  ? 310 PHE   A CG  1 
ATOM   2301 C CD1 . PHE   A 1 284 ? 127.325 141.944 141.581 1.00 62.30  ? 310 PHE   A CD1 1 
ATOM   2302 C CD2 . PHE   A 1 284 ? 125.819 140.247 142.285 1.00 62.19  ? 310 PHE   A CD2 1 
ATOM   2303 C CE1 . PHE   A 1 284 ? 128.377 141.236 142.117 1.00 62.28  ? 310 PHE   A CE1 1 
ATOM   2304 C CE2 . PHE   A 1 284 ? 126.868 139.537 142.821 1.00 61.01  ? 310 PHE   A CE2 1 
ATOM   2305 C CZ  . PHE   A 1 284 ? 128.148 140.031 142.737 1.00 58.66  ? 310 PHE   A CZ  1 
ATOM   2306 N N   . CYS   A 1 285 ? 123.193 143.457 138.324 1.00 70.63  ? 311 CYS   A N   1 
ATOM   2307 C CA  . CYS   A 1 285 ? 121.918 143.983 137.867 1.00 67.00  ? 311 CYS   A CA  1 
ATOM   2308 C C   . CYS   A 1 285 ? 121.217 142.950 136.987 1.00 67.33  ? 311 CYS   A C   1 
ATOM   2309 O O   . CYS   A 1 285 ? 121.719 141.848 136.750 1.00 66.19  ? 311 CYS   A O   1 
ATOM   2310 C CB  . CYS   A 1 285 ? 122.125 145.298 137.118 1.00 65.97  ? 311 CYS   A CB  1 
ATOM   2311 S SG  . CYS   A 1 285 ? 122.815 146.626 138.122 1.00 88.03  ? 311 CYS   A SG  1 
ATOM   2312 N N   . SER   A 1 286 ? 120.032 143.308 136.509 1.00 69.80  ? 312 SER   A N   1 
ATOM   2313 C CA  . SER   A 1 286 ? 119.274 142.394 135.673 1.00 65.00  ? 312 SER   A CA  1 
ATOM   2314 C C   . SER   A 1 286 ? 120.029 142.152 134.367 1.00 65.77  ? 312 SER   A C   1 
ATOM   2315 O O   . SER   A 1 286 ? 120.726 143.051 133.884 1.00 71.89  ? 312 SER   A O   1 
ATOM   2316 C CB  . SER   A 1 286 ? 117.883 142.960 135.388 1.00 69.05  ? 312 SER   A CB  1 
ATOM   2317 O OG  . SER   A 1 286 ? 117.963 144.277 134.875 1.00 70.58  ? 312 SER   A OG  1 
ATOM   2318 N N   . PRO   A 1 287 ? 119.924 140.962 133.761 1.00 63.26  ? 313 PRO   A N   1 
ATOM   2319 C CA  . PRO   A 1 287 ? 120.757 140.677 132.582 1.00 58.17  ? 313 PRO   A CA  1 
ATOM   2320 C C   . PRO   A 1 287 ? 120.404 141.479 131.338 1.00 60.70  ? 313 PRO   A C   1 
ATOM   2321 O O   . PRO   A 1 287 ? 121.113 141.349 130.334 1.00 65.78  ? 313 PRO   A O   1 
ATOM   2322 C CB  . PRO   A 1 287 ? 120.519 139.178 132.333 1.00 58.19  ? 313 PRO   A CB  1 
ATOM   2323 C CG  . PRO   A 1 287 ? 119.859 138.663 133.546 1.00 62.83  ? 313 PRO   A CG  1 
ATOM   2324 C CD  . PRO   A 1 287 ? 119.089 139.797 134.107 1.00 67.55  ? 313 PRO   A CD  1 
ATOM   2325 N N   . GLU   A 1 288 ? 119.349 142.300 131.363 1.00 65.12  ? 314 GLU   A N   1 
ATOM   2326 C CA  . GLU   A 1 288 ? 118.851 142.996 130.180 1.00 68.98  ? 314 GLU   A CA  1 
ATOM   2327 C C   . GLU   A 1 288 ? 118.866 144.512 130.340 1.00 68.56  ? 314 GLU   A C   1 
ATOM   2328 O O   . GLU   A 1 288 ? 118.175 145.210 129.593 1.00 72.75  ? 314 GLU   A O   1 
ATOM   2329 C CB  . GLU   A 1 288 ? 117.435 142.520 129.849 1.00 69.97  ? 314 GLU   A CB  1 
ATOM   2330 C CG  . GLU   A 1 288 ? 116.409 142.771 130.944 1.00 71.25  ? 314 GLU   A CG  1 
ATOM   2331 C CD  . GLU   A 1 288 ? 115.051 142.192 130.607 1.00 79.11  ? 314 GLU   A CD  1 
ATOM   2332 O OE1 . GLU   A 1 288 ? 114.911 141.596 129.519 1.00 81.72  ? 314 GLU   A OE1 1 
ATOM   2333 O OE2 . GLU   A 1 288 ? 114.123 142.331 131.431 1.00 85.43  ? 314 GLU   A OE2 1 
ATOM   2334 N N   . TRP   A 1 289 ? 119.624 145.041 131.301 1.00 64.20  ? 315 TRP   A N   1 
ATOM   2335 C CA  . TRP   A 1 289 ? 119.618 146.485 131.514 1.00 64.21  ? 315 TRP   A CA  1 
ATOM   2336 C C   . TRP   A 1 289 ? 120.095 147.298 130.309 1.00 68.60  ? 315 TRP   A C   1 
ATOM   2337 O O   . TRP   A 1 289 ? 119.477 148.344 130.042 1.00 77.71  ? 315 TRP   A O   1 
ATOM   2338 C CB  . TRP   A 1 289 ? 120.405 146.842 132.787 1.00 62.26  ? 315 TRP   A CB  1 
ATOM   2339 C CG  . TRP   A 1 289 ? 121.895 146.665 132.761 1.00 62.41  ? 315 TRP   A CG  1 
ATOM   2340 C CD1 . TRP   A 1 289 ? 122.594 145.544 133.101 1.00 66.47  ? 315 TRP   A CD1 1 
ATOM   2341 C CD2 . TRP   A 1 289 ? 122.872 147.652 132.412 1.00 65.78  ? 315 TRP   A CD2 1 
ATOM   2342 N NE1 . TRP   A 1 289 ? 123.941 145.765 132.969 1.00 64.30  ? 315 TRP   A NE1 1 
ATOM   2343 C CE2 . TRP   A 1 289 ? 124.139 147.053 132.549 1.00 64.88  ? 315 TRP   A CE2 1 
ATOM   2344 C CE3 . TRP   A 1 289 ? 122.799 148.982 131.991 1.00 67.57  ? 315 TRP   A CE3 1 
ATOM   2345 C CZ2 . TRP   A 1 289 ? 125.320 147.736 132.279 1.00 65.26  ? 315 TRP   A CZ2 1 
ATOM   2346 C CZ3 . TRP   A 1 289 ? 123.973 149.658 131.723 1.00 69.21  ? 315 TRP   A CZ3 1 
ATOM   2347 C CH2 . TRP   A 1 289 ? 125.217 149.034 131.869 1.00 65.97  ? 315 TRP   A CH2 1 
ATOM   2348 N N   . PRO   A 1 290 ? 121.146 146.924 129.560 1.00 67.08  ? 316 PRO   A N   1 
ATOM   2349 C CA  . PRO   A 1 290 ? 121.538 147.783 128.432 1.00 66.88  ? 316 PRO   A CA  1 
ATOM   2350 C C   . PRO   A 1 290 ? 120.478 147.883 127.353 1.00 68.99  ? 316 PRO   A C   1 
ATOM   2351 O O   . PRO   A 1 290 ? 120.334 148.948 126.742 1.00 78.94  ? 316 PRO   A O   1 
ATOM   2352 C CB  . PRO   A 1 290 ? 122.818 147.115 127.905 1.00 65.29  ? 316 PRO   A CB  1 
ATOM   2353 C CG  . PRO   A 1 290 ? 123.219 146.140 128.950 1.00 69.05  ? 316 PRO   A CG  1 
ATOM   2354 C CD  . PRO   A 1 290 ? 121.930 145.680 129.517 1.00 70.15  ? 316 PRO   A CD  1 
ATOM   2355 N N   . ARG   A 1 291 ? 119.713 146.817 127.112 1.00 63.95  ? 317 ARG   A N   1 
ATOM   2356 C CA  . ARG   A 1 291 ? 118.712 146.857 126.051 1.00 66.12  ? 317 ARG   A CA  1 
ATOM   2357 C C   . ARG   A 1 291 ? 117.604 147.847 126.382 1.00 71.35  ? 317 ARG   A C   1 
ATOM   2358 O O   . ARG   A 1 291 ? 117.244 148.692 125.554 1.00 81.10  ? 317 ARG   A O   1 
ATOM   2359 C CB  . ARG   A 1 291 ? 118.139 145.458 125.815 1.00 69.70  ? 317 ARG   A CB  1 
ATOM   2360 C CG  . ARG   A 1 291 ? 117.013 145.415 124.789 1.00 77.33  ? 317 ARG   A CG  1 
ATOM   2361 C CD  . ARG   A 1 291 ? 116.658 143.999 124.361 1.00 77.36  ? 317 ARG   A CD  1 
ATOM   2362 N NE  . ARG   A 1 291 ? 117.695 143.379 123.541 1.00 72.64  ? 317 ARG   A NE  1 
ATOM   2363 C CZ  . ARG   A 1 291 ? 118.635 142.547 123.973 1.00 70.55  ? 317 ARG   A CZ  1 
ATOM   2364 N NH1 . ARG   A 1 291 ? 118.743 142.209 125.249 1.00 71.49  ? 317 ARG   A NH1 1 
ATOM   2365 N NH2 . ARG   A 1 291 ? 119.494 142.034 123.098 1.00 71.47  ? 317 ARG   A NH2 1 
ATOM   2366 N N   . LYS   A 1 292 ? 117.050 147.763 127.592 1.00 71.35  ? 318 LYS   A N   1 
ATOM   2367 C CA  . LYS   A 1 292 ? 115.993 148.694 127.967 1.00 74.86  ? 318 LYS   A CA  1 
ATOM   2368 C C   . LYS   A 1 292 ? 116.538 150.100 128.176 1.00 73.58  ? 318 LYS   A C   1 
ATOM   2369 O O   . LYS   A 1 292 ? 115.809 151.079 127.979 1.00 81.14  ? 318 LYS   A O   1 
ATOM   2370 C CB  . LYS   A 1 292 ? 115.257 148.201 129.216 1.00 71.92  ? 318 LYS   A CB  1 
ATOM   2371 C CG  . LYS   A 1 292 ? 116.112 147.966 130.449 1.00 73.11  ? 318 LYS   A CG  1 
ATOM   2372 C CD  . LYS   A 1 292 ? 115.245 147.503 131.612 1.00 74.08  ? 318 LYS   A CD  1 
ATOM   2373 C CE  . LYS   A 1 292 ? 116.075 147.031 132.789 1.00 75.03  ? 318 LYS   A CE  1 
ATOM   2374 N NZ  . LYS   A 1 292 ? 115.228 146.615 133.939 1.00 83.54  ? 318 LYS   A NZ  1 
ATOM   2375 N N   . LEU   A 1 293 ? 117.806 150.227 128.573 1.00 67.41  ? 319 LEU   A N   1 
ATOM   2376 C CA  . LEU   A 1 293 ? 118.420 151.548 128.640 1.00 72.03  ? 319 LEU   A CA  1 
ATOM   2377 C C   . LEU   A 1 293 ? 118.506 152.183 127.257 1.00 83.99  ? 319 LEU   A C   1 
ATOM   2378 O O   . LEU   A 1 293 ? 118.229 153.377 127.093 1.00 89.04  ? 319 LEU   A O   1 
ATOM   2379 C CB  . LEU   A 1 293 ? 119.806 151.445 129.274 1.00 73.06  ? 319 LEU   A CB  1 
ATOM   2380 C CG  . LEU   A 1 293 ? 120.447 152.747 129.756 1.00 74.78  ? 319 LEU   A CG  1 
ATOM   2381 C CD1 . LEU   A 1 293 ? 119.709 153.308 130.964 1.00 75.47  ? 319 LEU   A CD1 1 
ATOM   2382 C CD2 . LEU   A 1 293 ? 121.914 152.522 130.082 1.00 74.18  ? 319 LEU   A CD2 1 
ATOM   2383 N N   . VAL   A 1 294 ? 118.894 151.398 126.249 1.00 89.20  ? 320 VAL   A N   1 
ATOM   2384 C CA  . VAL   A 1 294 ? 118.941 151.899 124.878 1.00 81.25  ? 320 VAL   A CA  1 
ATOM   2385 C C   . VAL   A 1 294 ? 117.538 152.206 124.374 1.00 85.28  ? 320 VAL   A C   1 
ATOM   2386 O O   . VAL   A 1 294 ? 117.339 153.136 123.585 1.00 92.40  ? 320 VAL   A O   1 
ATOM   2387 C CB  . VAL   A 1 294 ? 119.664 150.889 123.968 1.00 75.80  ? 320 VAL   A CB  1 
ATOM   2388 C CG1 . VAL   A 1 294 ? 119.464 151.233 122.502 1.00 79.10  ? 320 VAL   A CG1 1 
ATOM   2389 C CG2 . VAL   A 1 294 ? 121.146 150.852 124.294 1.00 82.89  ? 320 VAL   A CG2 1 
ATOM   2390 N N   . SER   A 1 295 ? 116.547 151.417 124.801 1.00 85.01  ? 321 SER   A N   1 
ATOM   2391 C CA  . SER   A 1 295 ? 115.172 151.662 124.378 1.00 89.61  ? 321 SER   A CA  1 
ATOM   2392 C C   . SER   A 1 295 ? 114.691 153.042 124.807 1.00 98.18  ? 321 SER   A C   1 
ATOM   2393 O O   . SER   A 1 295 ? 113.867 153.652 124.116 1.00 104.59 ? 321 SER   A O   1 
ATOM   2394 C CB  . SER   A 1 295 ? 114.249 150.582 124.939 1.00 87.35  ? 321 SER   A CB  1 
ATOM   2395 O OG  . SER   A 1 295 ? 114.575 149.309 124.409 1.00 86.62  ? 321 SER   A OG  1 
ATOM   2396 N N   . TYR   A 1 296 ? 115.192 153.551 125.933 1.00 98.36  ? 322 TYR   A N   1 
ATOM   2397 C CA  . TYR   A 1 296 ? 114.906 154.919 126.354 1.00 99.60  ? 322 TYR   A CA  1 
ATOM   2398 C C   . TYR   A 1 296 ? 115.851 155.902 125.674 1.00 100.64 ? 322 TYR   A C   1 
ATOM   2399 O O   . TYR   A 1 296 ? 116.573 156.641 126.350 1.00 99.44  ? 322 TYR   A O   1 
ATOM   2400 C CB  . TYR   A 1 296 ? 115.019 155.059 127.878 1.00 98.28  ? 322 TYR   A CB  1 
ATOM   2401 C CG  . TYR   A 1 296 ? 114.053 154.218 128.698 1.00 103.19 ? 322 TYR   A CG  1 
ATOM   2402 C CD1 . TYR   A 1 296 ? 112.870 153.725 128.153 1.00 104.43 ? 322 TYR   A CD1 1 
ATOM   2403 C CD2 . TYR   A 1 296 ? 114.325 153.929 130.029 1.00 102.11 ? 322 TYR   A CD2 1 
ATOM   2404 C CE1 . TYR   A 1 296 ? 111.997 152.965 128.908 1.00 105.43 ? 322 TYR   A CE1 1 
ATOM   2405 C CE2 . TYR   A 1 296 ? 113.457 153.170 130.789 1.00 106.20 ? 322 TYR   A CE2 1 
ATOM   2406 C CZ  . TYR   A 1 296 ? 112.295 152.692 130.225 1.00 107.77 ? 322 TYR   A CZ  1 
ATOM   2407 O OH  . TYR   A 1 296 ? 111.427 151.936 130.980 1.00 105.67 ? 322 TYR   A OH  1 
ATOM   2408 N N   . CYS   A 1 297 ? 115.859 155.909 124.344 1.00 106.93 ? 323 CYS   A N   1 
ATOM   2409 C CA  . CYS   A 1 297 ? 116.629 156.852 123.548 1.00 115.71 ? 323 CYS   A CA  1 
ATOM   2410 C C   . CYS   A 1 297 ? 115.795 157.262 122.342 1.00 118.82 ? 323 CYS   A C   1 
ATOM   2411 O O   . CYS   A 1 297 ? 114.903 156.512 121.929 1.00 114.47 ? 323 CYS   A O   1 
ATOM   2412 C CB  . CYS   A 1 297 ? 117.959 156.248 123.074 1.00 117.06 ? 323 CYS   A CB  1 
ATOM   2413 S SG  . CYS   A 1 297 ? 119.081 155.775 124.409 1.00 123.78 ? 323 CYS   A SG  1 
ATOM   2414 N N   . PRO   A 1 298 ? 116.051 158.435 121.757 1.00 123.48 ? 324 PRO   A N   1 
ATOM   2415 C CA  . PRO   A 1 298 ? 115.347 158.799 120.521 1.00 119.50 ? 324 PRO   A CA  1 
ATOM   2416 C C   . PRO   A 1 298 ? 115.709 157.859 119.382 1.00 119.50 ? 324 PRO   A C   1 
ATOM   2417 O O   . PRO   A 1 298 ? 116.620 157.034 119.472 1.00 121.60 ? 324 PRO   A O   1 
ATOM   2418 C CB  . PRO   A 1 298 ? 115.822 160.226 120.236 1.00 122.39 ? 324 PRO   A CB  1 
ATOM   2419 C CG  . PRO   A 1 298 ? 116.267 160.746 121.538 1.00 124.65 ? 324 PRO   A CG  1 
ATOM   2420 C CD  . PRO   A 1 298 ? 116.835 159.574 122.272 1.00 122.17 ? 324 PRO   A CD  1 
ATOM   2421 N N   . ARG   A 1 299 ? 114.966 158.004 118.283 1.00 123.46 ? 325 ARG   A N   1 
ATOM   2422 C CA  . ARG   A 1 299 ? 115.158 157.124 117.135 1.00 128.34 ? 325 ARG   A CA  1 
ATOM   2423 C C   . ARG   A 1 299 ? 116.548 157.288 116.534 1.00 128.90 ? 325 ARG   A C   1 
ATOM   2424 O O   . ARG   A 1 299 ? 117.178 156.302 116.134 1.00 126.10 ? 325 ARG   A O   1 
ATOM   2425 C CB  . ARG   A 1 299 ? 114.080 157.398 116.083 1.00 128.23 ? 325 ARG   A CB  1 
ATOM   2426 C CG  . ARG   A 1 299 ? 114.035 156.400 114.922 1.00 130.20 ? 325 ARG   A CG  1 
ATOM   2427 C CD  . ARG   A 1 299 ? 113.587 155.014 115.370 1.00 130.51 ? 325 ARG   A CD  1 
ATOM   2428 N NE  . ARG   A 1 299 ? 113.432 154.098 114.245 1.00 130.21 ? 325 ARG   A NE  1 
ATOM   2429 C CZ  . ARG   A 1 299 ? 113.058 152.828 114.346 1.00 124.45 ? 325 ARG   A CZ  1 
ATOM   2430 N NH1 . ARG   A 1 299 ? 112.783 152.273 115.517 1.00 119.82 ? 325 ARG   A NH1 1 
ATOM   2431 N NH2 . ARG   A 1 299 ? 112.955 152.094 113.242 1.00 125.64 ? 325 ARG   A NH2 1 
ATOM   2432 N N   . ARG   A 1 300 ? 117.040 158.528 116.455 1.00 127.54 ? 326 ARG   A N   1 
ATOM   2433 C CA  . ARG   A 1 300 ? 118.315 158.782 115.787 1.00 126.89 ? 326 ARG   A CA  1 
ATOM   2434 C C   . ARG   A 1 300 ? 119.469 158.077 116.491 1.00 127.00 ? 326 ARG   A C   1 
ATOM   2435 O O   . ARG   A 1 300 ? 120.341 157.496 115.835 1.00 125.13 ? 326 ARG   A O   1 
ATOM   2436 C CB  . ARG   A 1 300 ? 118.573 160.286 115.714 1.00 126.48 ? 326 ARG   A CB  1 
ATOM   2437 C CG  . ARG   A 1 300 ? 117.539 161.049 114.902 1.00 130.02 ? 326 ARG   A CG  1 
ATOM   2438 C CD  . ARG   A 1 300 ? 117.861 162.533 114.841 1.00 137.13 ? 326 ARG   A CD  1 
ATOM   2439 N NE  . ARG   A 1 300 ? 116.868 163.277 114.074 1.00 140.79 ? 326 ARG   A NE  1 
ATOM   2440 C CZ  . ARG   A 1 300 ? 116.889 164.589 113.875 1.00 142.06 ? 326 ARG   A CZ  1 
ATOM   2441 N NH1 . ARG   A 1 300 ? 117.848 165.355 114.375 1.00 138.65 ? 326 ARG   A NH1 1 
ATOM   2442 N NH2 . ARG   A 1 300 ? 115.922 165.150 113.155 1.00 142.26 ? 326 ARG   A NH2 1 
ATOM   2443 N N   . LEU   A 1 301 ? 119.497 158.122 117.825 1.00 128.83 ? 327 LEU   A N   1 
ATOM   2444 C CA  . LEU   A 1 301 ? 120.555 157.435 118.561 1.00 127.20 ? 327 LEU   A CA  1 
ATOM   2445 C C   . LEU   A 1 301 ? 120.484 155.928 118.351 1.00 124.52 ? 327 LEU   A C   1 
ATOM   2446 O O   . LEU   A 1 301 ? 121.518 155.261 118.228 1.00 121.14 ? 327 LEU   A O   1 
ATOM   2447 C CB  . LEU   A 1 301 ? 120.470 157.773 120.051 1.00 127.49 ? 327 LEU   A CB  1 
ATOM   2448 C CG  . LEU   A 1 301 ? 120.618 159.242 120.466 1.00 131.22 ? 327 LEU   A CG  1 
ATOM   2449 C CD1 . LEU   A 1 301 ? 120.598 159.365 121.983 1.00 127.01 ? 327 LEU   A CD1 1 
ATOM   2450 C CD2 . LEU   A 1 301 ? 121.890 159.867 119.907 1.00 129.45 ? 327 LEU   A CD2 1 
ATOM   2451 N N   . GLN   A 1 302 ? 119.270 155.372 118.304 1.00 122.98 ? 328 GLN   A N   1 
ATOM   2452 C CA  . GLN   A 1 302 ? 119.110 153.930 118.141 1.00 116.49 ? 328 GLN   A CA  1 
ATOM   2453 C C   . GLN   A 1 302 ? 119.625 153.426 116.799 1.00 114.16 ? 328 GLN   A C   1 
ATOM   2454 O O   . GLN   A 1 302 ? 119.898 152.229 116.670 1.00 112.82 ? 328 GLN   A O   1 
ATOM   2455 C CB  . GLN   A 1 302 ? 117.639 153.545 118.301 1.00 115.79 ? 328 GLN   A CB  1 
ATOM   2456 C CG  . GLN   A 1 302 ? 117.105 153.718 119.712 1.00 117.85 ? 328 GLN   A CG  1 
ATOM   2457 C CD  . GLN   A 1 302 ? 115.628 153.394 119.821 1.00 117.45 ? 328 GLN   A CD  1 
ATOM   2458 O OE1 . GLN   A 1 302 ? 115.018 152.898 118.873 1.00 114.41 ? 328 GLN   A OE1 1 
ATOM   2459 N NE2 . GLN   A 1 302 ? 115.045 153.675 120.980 1.00 112.06 ? 328 GLN   A NE2 1 
ATOM   2460 N N   . GLN   A 1 303 ? 119.762 154.302 115.800 1.00 117.75 ? 329 GLN   A N   1 
ATOM   2461 C CA  . GLN   A 1 303 ? 120.192 153.861 114.478 1.00 123.96 ? 329 GLN   A CA  1 
ATOM   2462 C C   . GLN   A 1 303 ? 121.613 153.306 114.471 1.00 118.12 ? 329 GLN   A C   1 
ATOM   2463 O O   . GLN   A 1 303 ? 121.959 152.554 113.553 1.00 112.57 ? 329 GLN   A O   1 
ATOM   2464 C CB  . GLN   A 1 303 ? 120.093 155.019 113.483 1.00 128.45 ? 329 GLN   A CB  1 
ATOM   2465 C CG  . GLN   A 1 303 ? 118.669 155.424 113.138 1.00 131.33 ? 329 GLN   A CG  1 
ATOM   2466 C CD  . GLN   A 1 303 ? 118.612 156.667 112.271 1.00 135.66 ? 329 GLN   A CD  1 
ATOM   2467 O OE1 . GLN   A 1 303 ? 119.637 157.151 111.791 1.00 135.08 ? 329 GLN   A OE1 1 
ATOM   2468 N NE2 . GLN   A 1 303 ? 117.409 157.192 112.067 1.00 134.26 ? 329 GLN   A NE2 1 
ATOM   2469 N N   . LEU   A 1 304 ? 122.437 153.655 115.466 1.00 116.13 ? 330 LEU   A N   1 
ATOM   2470 C CA  . LEU   A 1 304 ? 123.831 153.234 115.524 1.00 115.55 ? 330 LEU   A CA  1 
ATOM   2471 C C   . LEU   A 1 304 ? 124.157 152.338 116.707 1.00 114.89 ? 330 LEU   A C   1 
ATOM   2472 O O   . LEU   A 1 304 ? 125.119 151.567 116.623 1.00 115.78 ? 330 LEU   A O   1 
ATOM   2473 C CB  . LEU   A 1 304 ? 124.758 154.460 115.578 1.00 118.44 ? 330 LEU   A CB  1 
ATOM   2474 C CG  . LEU   A 1 304 ? 124.590 155.498 114.464 1.00 121.85 ? 330 LEU   A CG  1 
ATOM   2475 C CD1 . LEU   A 1 304 ? 125.547 156.660 114.677 1.00 119.16 ? 330 LEU   A CD1 1 
ATOM   2476 C CD2 . LEU   A 1 304 ? 124.801 154.877 113.089 1.00 121.23 ? 330 LEU   A CD2 1 
ATOM   2477 N N   . LEU   A 1 305 ? 123.396 152.411 117.797 1.00 110.70 ? 331 LEU   A N   1 
ATOM   2478 C CA  . LEU   A 1 305 ? 123.623 151.550 118.941 1.00 97.35  ? 331 LEU   A CA  1 
ATOM   2479 C C   . LEU   A 1 305 ? 123.209 150.123 118.586 1.00 89.11  ? 331 LEU   A C   1 
ATOM   2480 O O   . LEU   A 1 305 ? 122.607 149.887 117.537 1.00 92.53  ? 331 LEU   A O   1 
ATOM   2481 C CB  . LEU   A 1 305 ? 122.846 152.076 120.148 1.00 99.42  ? 331 LEU   A CB  1 
ATOM   2482 C CG  . LEU   A 1 305 ? 123.184 153.497 120.604 1.00 103.02 ? 331 LEU   A CG  1 
ATOM   2483 C CD1 . LEU   A 1 305 ? 122.244 153.936 121.715 1.00 106.96 ? 331 LEU   A CD1 1 
ATOM   2484 C CD2 . LEU   A 1 305 ? 124.632 153.599 121.062 1.00 99.39  ? 331 LEU   A CD2 1 
ATOM   2485 N N   . PRO   A 1 306 ? 123.531 149.142 119.432 1.00 79.47  ? 332 PRO   A N   1 
ATOM   2486 C CA  . PRO   A 1 306 ? 123.127 147.759 119.143 1.00 81.95  ? 332 PRO   A CA  1 
ATOM   2487 C C   . PRO   A 1 306 ? 121.616 147.600 119.060 1.00 79.67  ? 332 PRO   A C   1 
ATOM   2488 O O   . PRO   A 1 306 ? 120.836 148.503 119.373 1.00 85.31  ? 332 PRO   A O   1 
ATOM   2489 C CB  . PRO   A 1 306 ? 123.712 146.971 120.316 1.00 78.16  ? 332 PRO   A CB  1 
ATOM   2490 C CG  . PRO   A 1 306 ? 124.881 147.757 120.734 1.00 76.38  ? 332 PRO   A CG  1 
ATOM   2491 C CD  . PRO   A 1 306 ? 124.500 149.190 120.543 1.00 81.82  ? 332 PRO   A CD  1 
ATOM   2492 N N   . LEU   A 1 307 ? 121.206 146.410 118.627 1.00 73.37  ? 333 LEU   A N   1 
ATOM   2493 C CA  . LEU   A 1 307 ? 119.804 146.143 118.340 1.00 72.29  ? 333 LEU   A CA  1 
ATOM   2494 C C   . LEU   A 1 307 ? 118.953 146.221 119.601 1.00 79.16  ? 333 LEU   A C   1 
ATOM   2495 O O   . LEU   A 1 307 ? 119.419 145.962 120.714 1.00 79.86  ? 333 LEU   A O   1 
ATOM   2496 C CB  . LEU   A 1 307 ? 119.641 144.763 117.703 1.00 73.14  ? 333 LEU   A CB  1 
ATOM   2497 C CG  . LEU   A 1 307 ? 120.223 144.554 116.305 1.00 78.39  ? 333 LEU   A CG  1 
ATOM   2498 C CD1 . LEU   A 1 307 ? 120.101 143.095 115.904 1.00 78.43  ? 333 LEU   A CD1 1 
ATOM   2499 C CD2 . LEU   A 1 307 ? 119.533 145.445 115.285 1.00 79.38  ? 333 LEU   A CD2 1 
ATOM   2500 N N   . LYS   A 1 308 ? 117.685 146.584 119.405 1.00 84.67  ? 334 LYS   A N   1 
ATOM   2501 C CA  . LYS   A 1 308 ? 116.697 146.666 120.471 1.00 83.40  ? 334 LYS   A CA  1 
ATOM   2502 C C   . LYS   A 1 308 ? 115.664 145.550 120.406 1.00 78.09  ? 334 LYS   A C   1 
ATOM   2503 O O   . LYS   A 1 308 ? 114.799 145.476 121.284 1.00 78.21  ? 334 LYS   A O   1 
ATOM   2504 C CB  . LYS   A 1 308 ? 115.984 148.025 120.426 1.00 85.39  ? 334 LYS   A CB  1 
ATOM   2505 C CG  . LYS   A 1 308 ? 115.239 148.313 119.127 1.00 93.89  ? 334 LYS   A CG  1 
ATOM   2506 C CD  . LYS   A 1 308 ? 114.602 149.694 119.149 1.00 102.83 ? 334 LYS   A CD  1 
ATOM   2507 C CE  . LYS   A 1 308 ? 113.821 149.971 117.872 1.00 109.06 ? 334 LYS   A CE  1 
ATOM   2508 N NZ  . LYS   A 1 308 ? 114.691 149.965 116.663 1.00 110.64 ? 334 LYS   A NZ  1 
ATOM   2509 N N   . ALA   A 1 309 ? 115.724 144.685 119.397 1.00 77.25  ? 335 ALA   A N   1 
ATOM   2510 C CA  . ALA   A 1 309 ? 114.767 143.598 119.291 1.00 78.56  ? 335 ALA   A CA  1 
ATOM   2511 C C   . ALA   A 1 309 ? 115.005 142.571 120.392 1.00 70.17  ? 335 ALA   A C   1 
ATOM   2512 O O   . ALA   A 1 309 ? 116.084 142.488 120.983 1.00 67.17  ? 335 ALA   A O   1 
ATOM   2513 C CB  . ALA   A 1 309 ? 114.866 142.929 117.920 1.00 80.70  ? 335 ALA   A CB  1 
ATOM   2514 N N   . ALA   A 1 310 ? 113.969 141.786 120.669 1.00 68.40  ? 336 ALA   A N   1 
ATOM   2515 C CA  . ALA   A 1 310 ? 114.079 140.752 121.678 1.00 67.23  ? 336 ALA   A CA  1 
ATOM   2516 C C   . ALA   A 1 310 ? 115.052 139.669 121.207 1.00 64.53  ? 336 ALA   A C   1 
ATOM   2517 O O   . ALA   A 1 310 ? 115.182 139.428 120.004 1.00 64.47  ? 336 ALA   A O   1 
ATOM   2518 C CB  . ALA   A 1 310 ? 112.712 140.140 121.967 1.00 68.56  ? 336 ALA   A CB  1 
ATOM   2519 N N   . PRO   A 1 311 ? 115.755 139.006 122.127 1.00 58.89  ? 337 PRO   A N   1 
ATOM   2520 C CA  . PRO   A 1 311 ? 116.749 138.015 121.703 1.00 54.33  ? 337 PRO   A CA  1 
ATOM   2521 C C   . PRO   A 1 311 ? 116.100 136.815 121.038 1.00 51.51  ? 337 PRO   A C   1 
ATOM   2522 O O   . PRO   A 1 311 ? 114.950 136.468 121.316 1.00 54.46  ? 337 PRO   A O   1 
ATOM   2523 C CB  . PRO   A 1 311 ? 117.439 137.620 123.012 1.00 60.09  ? 337 PRO   A CB  1 
ATOM   2524 C CG  . PRO   A 1 311 ? 116.433 137.894 124.058 1.00 66.38  ? 337 PRO   A CG  1 
ATOM   2525 C CD  . PRO   A 1 311 ? 115.673 139.093 123.596 1.00 64.82  ? 337 PRO   A CD  1 
ATOM   2526 N N   . GLN   A 1 312 ? 116.858 136.180 120.149 1.00 52.34  ? 338 GLN   A N   1 
ATOM   2527 C CA  . GLN   A 1 312 ? 116.406 135.005 119.422 1.00 54.73  ? 338 GLN   A CA  1 
ATOM   2528 C C   . GLN   A 1 312 ? 116.864 133.730 120.120 1.00 58.92  ? 338 GLN   A C   1 
ATOM   2529 O O   . GLN   A 1 312 ? 117.757 133.767 120.973 1.00 66.55  ? 338 GLN   A O   1 
ATOM   2530 C CB  . GLN   A 1 312 ? 116.927 135.033 117.979 1.00 56.50  ? 338 GLN   A CB  1 
ATOM   2531 C CG  . GLN   A 1 312 ? 118.439 135.042 117.821 1.00 59.75  ? 338 GLN   A CG  1 
ATOM   2532 C CD  . GLN   A 1 312 ? 118.863 134.928 116.373 1.00 64.97  ? 338 GLN   A CD  1 
ATOM   2533 O OE1 . GLN   A 1 312 ? 118.067 135.153 115.464 1.00 67.04  ? 338 GLN   A OE1 1 
ATOM   2534 N NE2 . GLN   A 1 312 ? 120.120 134.568 116.151 1.00 68.22  ? 338 GLN   A NE2 1 
ATOM   2535 N N   . PRO   A 1 313 ? 116.272 132.577 119.795 1.00 52.37  ? 339 PRO   A N   1 
ATOM   2536 C CA  . PRO   A 1 313 ? 116.704 131.329 120.436 1.00 53.07  ? 339 PRO   A CA  1 
ATOM   2537 C C   . PRO   A 1 313 ? 118.151 130.985 120.116 1.00 57.37  ? 339 PRO   A C   1 
ATOM   2538 O O   . PRO   A 1 313 ? 118.678 131.333 119.057 1.00 62.93  ? 339 PRO   A O   1 
ATOM   2539 C CB  . PRO   A 1 313 ? 115.750 130.280 119.855 1.00 53.71  ? 339 PRO   A CB  1 
ATOM   2540 C CG  . PRO   A 1 313 ? 114.583 131.033 119.388 1.00 53.67  ? 339 PRO   A CG  1 
ATOM   2541 C CD  . PRO   A 1 313 ? 115.095 132.356 118.935 1.00 51.37  ? 339 PRO   A CD  1 
ATOM   2542 N N   . SER   A 1 314 ? 118.786 130.291 121.054 1.00 59.73  ? 340 SER   A N   1 
ATOM   2543 C CA  . SER   A 1 314 ? 120.129 129.751 120.905 1.00 60.96  ? 340 SER   A CA  1 
ATOM   2544 C C   . SER   A 1 314 ? 120.069 128.229 120.884 1.00 65.60  ? 340 SER   A C   1 
ATOM   2545 O O   . SER   A 1 314 ? 119.018 127.624 121.111 1.00 72.76  ? 340 SER   A O   1 
ATOM   2546 C CB  . SER   A 1 314 ? 121.039 130.235 122.039 1.00 64.69  ? 340 SER   A CB  1 
ATOM   2547 O OG  . SER   A 1 314 ? 122.340 129.689 121.917 1.00 70.92  ? 340 SER   A OG  1 
ATOM   2548 N N   . VAL   A 1 315 ? 121.221 127.615 120.609 1.00 64.75  ? 341 VAL   A N   1 
ATOM   2549 C CA  . VAL   A 1 315 ? 121.338 126.161 120.526 1.00 65.58  ? 341 VAL   A CA  1 
ATOM   2550 C C   . VAL   A 1 315 ? 122.096 125.563 121.703 1.00 72.44  ? 341 VAL   A C   1 
ATOM   2551 O O   . VAL   A 1 315 ? 122.118 124.329 121.837 1.00 73.61  ? 341 VAL   A O   1 
ATOM   2552 C CB  . VAL   A 1 315 ? 122.004 125.732 119.199 1.00 73.68  ? 341 VAL   A CB  1 
ATOM   2553 C CG1 . VAL   A 1 315 ? 123.508 126.016 119.227 1.00 79.84  ? 341 VAL   A CG1 1 
ATOM   2554 C CG2 . VAL   A 1 315 ? 121.725 124.259 118.884 1.00 73.73  ? 341 VAL   A CG2 1 
ATOM   2555 N N   . SER   A 1 316 ? 122.698 126.386 122.566 1.00 81.48  ? 342 SER   A N   1 
ATOM   2556 C CA  . SER   A 1 316 ? 123.436 125.921 123.734 1.00 81.96  ? 342 SER   A CA  1 
ATOM   2557 C C   . SER   A 1 316 ? 122.642 126.098 125.025 1.00 76.60  ? 342 SER   A C   1 
ATOM   2558 O O   . SER   A 1 316 ? 123.226 126.367 126.081 1.00 78.15  ? 342 SER   A O   1 
ATOM   2559 C CB  . SER   A 1 316 ? 124.777 126.650 123.830 1.00 82.63  ? 342 SER   A CB  1 
ATOM   2560 O OG  . SER   A 1 316 ? 124.594 128.049 123.957 1.00 75.49  ? 342 SER   A OG  1 
ATOM   2561 N N   . CYS   A 1 317 ? 121.318 125.958 124.959 1.00 65.87  ? 343 CYS   A N   1 
ATOM   2562 C CA  . CYS   A 1 317 ? 120.449 126.132 126.113 1.00 65.17  ? 343 CYS   A CA  1 
ATOM   2563 C C   . CYS   A 1 317 ? 119.316 125.118 126.046 1.00 76.23  ? 343 CYS   A C   1 
ATOM   2564 O O   . CYS   A 1 317 ? 118.977 124.607 124.976 1.00 81.56  ? 343 CYS   A O   1 
ATOM   2565 C CB  . CYS   A 1 317 ? 119.880 127.554 126.180 1.00 59.63  ? 343 CYS   A CB  1 
ATOM   2566 S SG  . CYS   A 1 317 ? 121.128 128.843 126.282 1.00 62.49  ? 343 CYS   A SG  1 
ATOM   2567 N N   . VAL   A 1 318 ? 118.732 124.836 127.209 1.00 72.56  ? 344 VAL   A N   1 
ATOM   2568 C CA  . VAL   A 1 318 ? 117.635 123.884 127.342 1.00 68.82  ? 344 VAL   A CA  1 
ATOM   2569 C C   . VAL   A 1 318 ? 116.335 124.669 127.434 1.00 72.25  ? 344 VAL   A C   1 
ATOM   2570 O O   . VAL   A 1 318 ? 116.131 125.436 128.382 1.00 68.84  ? 344 VAL   A O   1 
ATOM   2571 C CB  . VAL   A 1 318 ? 117.821 122.980 128.570 1.00 71.98  ? 344 VAL   A CB  1 
ATOM   2572 C CG1 . VAL   A 1 318 ? 116.677 121.974 128.672 1.00 80.02  ? 344 VAL   A CG1 1 
ATOM   2573 C CG2 . VAL   A 1 318 ? 119.167 122.270 128.512 1.00 75.75  ? 344 VAL   A CG2 1 
ATOM   2574 N N   . TYR   A 1 319 ? 115.455 124.471 126.453 1.00 77.35  ? 345 TYR   A N   1 
ATOM   2575 C CA  . TYR   A 1 319 ? 114.183 125.179 126.362 1.00 76.48  ? 345 TYR   A CA  1 
ATOM   2576 C C   . TYR   A 1 319 ? 113.045 124.249 126.758 1.00 83.30  ? 345 TYR   A C   1 
ATOM   2577 O O   . TYR   A 1 319 ? 112.942 123.132 126.240 1.00 93.36  ? 345 TYR   A O   1 
ATOM   2578 C CB  . TYR   A 1 319 ? 113.955 125.710 124.947 1.00 71.82  ? 345 TYR   A CB  1 
ATOM   2579 C CG  . TYR   A 1 319 ? 114.899 126.820 124.554 1.00 62.29  ? 345 TYR   A CG  1 
ATOM   2580 C CD1 . TYR   A 1 319 ? 114.617 128.139 124.872 1.00 59.00  ? 345 TYR   A CD1 1 
ATOM   2581 C CD2 . TYR   A 1 319 ? 116.069 126.550 123.867 1.00 59.23  ? 345 TYR   A CD2 1 
ATOM   2582 C CE1 . TYR   A 1 319 ? 115.472 129.153 124.518 1.00 56.20  ? 345 TYR   A CE1 1 
ATOM   2583 C CE2 . TYR   A 1 319 ? 116.931 127.559 123.511 1.00 60.10  ? 345 TYR   A CE2 1 
ATOM   2584 C CZ  . TYR   A 1 319 ? 116.628 128.859 123.839 1.00 62.09  ? 345 TYR   A CZ  1 
ATOM   2585 O OH  . TYR   A 1 319 ? 117.485 129.873 123.486 1.00 75.81  ? 345 TYR   A OH  1 
ATOM   2586 N N   . LYS   A 1 320 ? 112.192 124.715 127.666 1.00 91.78  ? 346 LYS   A N   1 
ATOM   2587 C CA  . LYS   A 1 320 ? 111.068 123.928 128.151 1.00 94.95  ? 346 LYS   A CA  1 
ATOM   2588 C C   . LYS   A 1 320 ? 109.853 124.147 127.264 1.00 95.53  ? 346 LYS   A C   1 
ATOM   2589 O O   . LYS   A 1 320 ? 109.571 125.272 126.841 1.00 97.43  ? 346 LYS   A O   1 
ATOM   2590 C CB  . LYS   A 1 320 ? 110.729 124.300 129.596 1.00 94.92  ? 346 LYS   A CB  1 
ATOM   2591 C CG  . LYS   A 1 320 ? 111.766 123.852 130.615 1.00 101.89 ? 346 LYS   A CG  1 
ATOM   2592 C CD  . LYS   A 1 320 ? 111.269 124.060 132.038 1.00 106.52 ? 346 LYS   A CD  1 
ATOM   2593 C CE  . LYS   A 1 320 ? 112.243 123.497 133.061 1.00 105.31 ? 346 LYS   A CE  1 
ATOM   2594 N NZ  . LYS   A 1 320 ? 111.728 123.621 134.454 1.00 105.14 ? 346 LYS   A NZ  1 
ATOM   2595 N N   . ARG   A 1 321 ? 109.137 123.063 126.984 1.00 99.35  ? 347 ARG   A N   1 
ATOM   2596 C CA  . ARG   A 1 321 ? 107.926 123.132 126.177 1.00 103.91 ? 347 ARG   A CA  1 
ATOM   2597 C C   . ARG   A 1 321 ? 106.722 123.450 127.053 1.00 99.20  ? 347 ARG   A C   1 
ATOM   2598 O O   . ARG   A 1 321 ? 106.816 123.434 128.280 1.00 100.56 ? 347 ARG   A O   1 
ATOM   2599 C CB  . ARG   A 1 321 ? 107.703 121.818 125.430 1.00 106.05 ? 347 ARG   A CB  1 
ATOM   2600 C CG  . ARG   A 1 321 ? 108.744 121.536 124.358 1.00 107.62 ? 347 ARG   A CG  1 
ATOM   2601 C CD  . ARG   A 1 321 ? 108.432 120.258 123.598 1.00 109.44 ? 347 ARG   A CD  1 
ATOM   2602 N NE  . ARG   A 1 321 ? 107.176 120.344 122.861 1.00 112.58 ? 347 ARG   A NE  1 
ATOM   2603 C CZ  . ARG   A 1 321 ? 106.642 119.354 122.156 1.00 117.64 ? 347 ARG   A CZ  1 
ATOM   2604 N NH1 . ARG   A 1 321 ? 107.225 118.169 122.065 1.00 118.43 ? 347 ARG   A NH1 1 
ATOM   2605 N NH2 . ARG   A 1 321 ? 105.489 119.559 121.524 1.00 118.38 ? 347 ARG   A NH2 1 
ATOM   2606 N N   . GLY   A 1 327 ? 109.626 118.659 126.437 1.00 107.46 ? 353 GLY   A N   1 
ATOM   2607 C CA  . GLY   A 1 327 ? 110.870 118.287 127.084 1.00 114.37 ? 353 GLY   A CA  1 
ATOM   2608 C C   . GLY   A 1 327 ? 112.016 118.125 126.105 1.00 118.99 ? 353 GLY   A C   1 
ATOM   2609 O O   . GLY   A 1 327 ? 111.871 117.466 125.075 1.00 117.29 ? 353 GLY   A O   1 
ATOM   2610 N N   . GLN   A 1 328 ? 113.157 118.731 126.434 1.00 120.63 ? 354 GLN   A N   1 
ATOM   2611 C CA  . GLN   A 1 328 ? 114.368 118.669 125.623 1.00 118.33 ? 354 GLN   A CA  1 
ATOM   2612 C C   . GLN   A 1 328 ? 115.437 117.928 126.411 1.00 119.43 ? 354 GLN   A C   1 
ATOM   2613 O O   . GLN   A 1 328 ? 115.753 118.308 127.543 1.00 114.85 ? 354 GLN   A O   1 
ATOM   2614 C CB  . GLN   A 1 328 ? 114.848 120.073 125.249 1.00 107.90 ? 354 GLN   A CB  1 
ATOM   2615 C CG  . GLN   A 1 328 ? 116.036 120.099 124.297 1.00 109.10 ? 354 GLN   A CG  1 
ATOM   2616 C CD  . GLN   A 1 328 ? 116.432 121.508 123.902 1.00 109.46 ? 354 GLN   A CD  1 
ATOM   2617 O OE1 . GLN   A 1 328 ? 115.788 122.480 124.296 1.00 103.70 ? 354 GLN   A OE1 1 
ATOM   2618 N NE2 . GLN   A 1 328 ? 117.499 121.625 123.120 1.00 107.35 ? 354 GLN   A NE2 1 
ATOM   2619 N N   . LYS   A 1 329 ? 115.991 116.878 125.815 1.00 121.88 ? 355 LYS   A N   1 
ATOM   2620 C CA  . LYS   A 1 329 ? 117.038 116.114 126.481 1.00 116.18 ? 355 LYS   A CA  1 
ATOM   2621 C C   . LYS   A 1 329 ? 118.347 116.903 126.446 1.00 113.53 ? 355 LYS   A C   1 
ATOM   2622 O O   . LYS   A 1 329 ? 118.771 117.325 125.365 1.00 114.77 ? 355 LYS   A O   1 
ATOM   2623 C CB  . LYS   A 1 329 ? 117.226 114.761 125.804 1.00 119.06 ? 355 LYS   A CB  1 
ATOM   2624 C CG  . LYS   A 1 329 ? 118.158 113.821 126.554 1.00 120.48 ? 355 LYS   A CG  1 
ATOM   2625 C CD  . LYS   A 1 329 ? 118.164 112.430 125.943 1.00 122.61 ? 355 LYS   A CD  1 
ATOM   2626 C CE  . LYS   A 1 329 ? 119.068 111.488 126.723 1.00 121.41 ? 355 LYS   A CE  1 
ATOM   2627 N NZ  . LYS   A 1 329 ? 119.076 110.113 126.154 1.00 124.25 ? 355 LYS   A NZ  1 
ATOM   2628 N N   . PRO   A 1 330 ? 119.009 117.140 127.586 1.00 102.80 ? 356 PRO   A N   1 
ATOM   2629 C CA  . PRO   A 1 330 ? 120.296 117.845 127.536 1.00 95.45  ? 356 PRO   A CA  1 
ATOM   2630 C C   . PRO   A 1 330 ? 121.348 117.068 126.760 1.00 100.83 ? 356 PRO   A C   1 
ATOM   2631 O O   . PRO   A 1 330 ? 121.372 115.835 126.758 1.00 106.57 ? 356 PRO   A O   1 
ATOM   2632 C CB  . PRO   A 1 330 ? 120.686 117.982 129.012 1.00 92.32  ? 356 PRO   A CB  1 
ATOM   2633 C CG  . PRO   A 1 330 ? 119.422 117.923 129.742 1.00 94.88  ? 356 PRO   A CG  1 
ATOM   2634 C CD  . PRO   A 1 330 ? 118.556 116.976 128.981 1.00 101.25 ? 356 PRO   A CD  1 
ATOM   2635 N N   . GLY   A 1 331 ? 122.227 117.813 126.093 1.00 99.10  ? 357 GLY   A N   1 
ATOM   2636 C CA  . GLY   A 1 331 ? 123.339 117.225 125.372 1.00 93.70  ? 357 GLY   A CA  1 
ATOM   2637 C C   . GLY   A 1 331 ? 124.527 116.975 126.274 1.00 85.68  ? 357 GLY   A C   1 
ATOM   2638 O O   . GLY   A 1 331 ? 124.361 116.505 127.404 1.00 89.57  ? 357 GLY   A O   1 
ATOM   2639 N N   . LEU   A 1 332 ? 125.727 117.291 125.791 1.00 75.75  ? 358 LEU   A N   1 
ATOM   2640 C CA  . LEU   A 1 332 ? 126.963 117.123 126.548 1.00 78.31  ? 358 LEU   A CA  1 
ATOM   2641 C C   . LEU   A 1 332 ? 127.528 118.432 127.075 1.00 83.18  ? 358 LEU   A C   1 
ATOM   2642 O O   . LEU   A 1 332 ? 127.979 118.482 128.221 1.00 87.48  ? 358 LEU   A O   1 
ATOM   2643 C CB  . LEU   A 1 332 ? 128.021 116.432 125.680 1.00 81.57  ? 358 LEU   A CB  1 
ATOM   2644 C CG  . LEU   A 1 332 ? 129.314 115.983 126.368 1.00 86.19  ? 358 LEU   A CG  1 
ATOM   2645 C CD1 . LEU   A 1 332 ? 129.042 114.934 127.436 1.00 82.58  ? 358 LEU   A CD1 1 
ATOM   2646 C CD2 . LEU   A 1 332 ? 130.297 115.451 125.337 1.00 87.13  ? 358 LEU   A CD2 1 
ATOM   2647 N N   . ARG   A 1 333 ? 127.526 119.495 126.266 1.00 80.85  ? 359 ARG   A N   1 
ATOM   2648 C CA  . ARG   A 1 333 ? 128.012 120.785 126.747 1.00 80.92  ? 359 ARG   A CA  1 
ATOM   2649 C C   . ARG   A 1 333 ? 127.156 121.315 127.890 1.00 81.34  ? 359 ARG   A C   1 
ATOM   2650 O O   . ARG   A 1 333 ? 127.668 122.004 128.783 1.00 80.96  ? 359 ARG   A O   1 
ATOM   2651 C CB  . ARG   A 1 333 ? 128.050 121.792 125.597 1.00 76.89  ? 359 ARG   A CB  1 
ATOM   2652 C CG  . ARG   A 1 333 ? 126.690 122.135 125.010 1.00 84.34  ? 359 ARG   A CG  1 
ATOM   2653 C CD  . ARG   A 1 333 ? 126.826 122.903 123.702 1.00 94.42  ? 359 ARG   A CD  1 
ATOM   2654 N NE  . ARG   A 1 333 ? 127.573 124.146 123.860 1.00 101.03 ? 359 ARG   A NE  1 
ATOM   2655 C CZ  . ARG   A 1 333 ? 127.864 124.986 122.874 1.00 101.90 ? 359 ARG   A CZ  1 
ATOM   2656 N NH1 . ARG   A 1 333 ? 127.488 124.753 121.625 1.00 99.13  ? 359 ARG   A NH1 1 
ATOM   2657 N NH2 . ARG   A 1 333 ? 128.553 126.090 123.147 1.00 92.09  ? 359 ARG   A NH2 1 
ATOM   2658 N N   . HIS   A 1 334 ? 125.861 120.991 127.889 1.00 74.11  ? 360 HIS   A N   1 
ATOM   2659 C CA  . HIS   A 1 334 ? 124.976 121.459 128.951 1.00 71.46  ? 360 HIS   A CA  1 
ATOM   2660 C C   . HIS   A 1 334 ? 125.398 120.904 130.304 1.00 72.48  ? 360 HIS   A C   1 
ATOM   2661 O O   . HIS   A 1 334 ? 125.405 121.627 131.307 1.00 76.20  ? 360 HIS   A O   1 
ATOM   2662 C CB  . HIS   A 1 334 ? 123.532 121.062 128.645 1.00 74.78  ? 360 HIS   A CB  1 
ATOM   2663 C CG  . HIS   A 1 334 ? 123.036 121.548 127.319 1.00 74.72  ? 360 HIS   A CG  1 
ATOM   2664 N ND1 . HIS   A 1 334 ? 123.348 120.922 126.132 1.00 73.99  ? 360 HIS   A ND1 1 
ATOM   2665 C CD2 . HIS   A 1 334 ? 122.247 122.598 126.993 1.00 76.10  ? 360 HIS   A CD2 1 
ATOM   2666 C CE1 . HIS   A 1 334 ? 122.775 121.566 125.132 1.00 76.07  ? 360 HIS   A CE1 1 
ATOM   2667 N NE2 . HIS   A 1 334 ? 122.101 122.588 125.628 1.00 77.20  ? 360 HIS   A NE2 1 
ATOM   2668 N N   . GLN   A 1 335 ? 125.752 119.619 130.353 1.00 75.51  ? 361 GLN   A N   1 
ATOM   2669 C CA  . GLN   A 1 335 ? 126.184 119.019 131.610 1.00 77.18  ? 361 GLN   A CA  1 
ATOM   2670 C C   . GLN   A 1 335 ? 127.555 119.539 132.023 1.00 73.54  ? 361 GLN   A C   1 
ATOM   2671 O O   . GLN   A 1 335 ? 127.799 119.813 133.209 1.00 76.45  ? 361 GLN   A O   1 
ATOM   2672 C CB  . GLN   A 1 335 ? 126.211 117.497 131.475 1.00 78.33  ? 361 GLN   A CB  1 
ATOM   2673 C CG  . GLN   A 1 335 ? 124.894 116.881 131.026 1.00 79.85  ? 361 GLN   A CG  1 
ATOM   2674 C CD  . GLN   A 1 335 ? 124.996 115.388 130.815 1.00 83.73  ? 361 GLN   A CD  1 
ATOM   2675 O OE1 . GLN   A 1 335 ? 125.977 114.759 131.206 1.00 83.00  ? 361 GLN   A OE1 1 
ATOM   2676 N NE2 . GLN   A 1 335 ? 123.980 114.812 130.186 1.00 85.25  ? 361 GLN   A NE2 1 
ATOM   2677 N N   . LEU   A 1 336 ? 128.464 119.672 131.055 1.00 66.99  ? 362 LEU   A N   1 
ATOM   2678 C CA  . LEU   A 1 336 ? 129.810 120.129 131.368 1.00 66.25  ? 362 LEU   A CA  1 
ATOM   2679 C C   . LEU   A 1 336 ? 129.807 121.561 131.877 1.00 73.40  ? 362 LEU   A C   1 
ATOM   2680 O O   . LEU   A 1 336 ? 130.673 121.930 132.673 1.00 81.22  ? 362 LEU   A O   1 
ATOM   2681 C CB  . LEU   A 1 336 ? 130.712 120.001 130.143 1.00 65.38  ? 362 LEU   A CB  1 
ATOM   2682 C CG  . LEU   A 1 336 ? 131.019 118.585 129.654 1.00 67.89  ? 362 LEU   A CG  1 
ATOM   2683 C CD1 . LEU   A 1 336 ? 131.817 118.638 128.362 1.00 71.66  ? 362 LEU   A CD1 1 
ATOM   2684 C CD2 . LEU   A 1 336 ? 131.772 117.787 130.704 1.00 68.90  ? 362 LEU   A CD2 1 
ATOM   2685 N N   . GLY   A 1 337 ? 128.845 122.379 131.447 1.00 71.23  ? 363 GLY   A N   1 
ATOM   2686 C CA  . GLY   A 1 337 ? 128.761 123.730 131.980 1.00 69.10  ? 363 GLY   A CA  1 
ATOM   2687 C C   . GLY   A 1 337 ? 128.490 123.745 133.473 1.00 66.28  ? 363 GLY   A C   1 
ATOM   2688 O O   . GLY   A 1 337 ? 129.163 124.445 134.237 1.00 69.16  ? 363 GLY   A O   1 
ATOM   2689 N N   . ALA   A 1 338 ? 127.513 122.949 133.913 1.00 64.68  ? 364 ALA   A N   1 
ATOM   2690 C CA  . ALA   A 1 338 ? 127.216 122.862 135.338 1.00 67.86  ? 364 ALA   A CA  1 
ATOM   2691 C C   . ALA   A 1 338 ? 128.388 122.266 136.107 1.00 71.34  ? 364 ALA   A C   1 
ATOM   2692 O O   . ALA   A 1 338 ? 128.727 122.736 137.205 1.00 78.07  ? 364 ALA   A O   1 
ATOM   2693 C CB  . ALA   A 1 338 ? 125.955 122.031 135.560 1.00 67.67  ? 364 ALA   A CB  1 
ATOM   2694 N N   . ALA   A 1 339 ? 129.010 121.221 135.552 1.00 65.66  ? 365 ALA   A N   1 
ATOM   2695 C CA  . ALA   A 1 339 ? 130.151 120.609 136.226 1.00 67.75  ? 365 ALA   A CA  1 
ATOM   2696 C C   . ALA   A 1 339 ? 131.287 121.609 136.394 1.00 67.59  ? 365 ALA   A C   1 
ATOM   2697 O O   . ALA   A 1 339 ? 131.881 121.714 137.476 1.00 73.67  ? 365 ALA   A O   1 
ATOM   2698 C CB  . ALA   A 1 339 ? 130.627 119.385 135.447 1.00 68.03  ? 365 ALA   A CB  1 
ATOM   2699 N N   . PHE   A 1 340 ? 131.589 122.369 135.338 1.00 61.29  ? 366 PHE   A N   1 
ATOM   2700 C CA  . PHE   A 1 340 ? 132.638 123.375 135.417 1.00 66.38  ? 366 PHE   A CA  1 
ATOM   2701 C C   . PHE   A 1 340 ? 132.295 124.446 136.438 1.00 68.56  ? 366 PHE   A C   1 
ATOM   2702 O O   . PHE   A 1 340 ? 133.161 124.866 137.210 1.00 70.80  ? 366 PHE   A O   1 
ATOM   2703 C CB  . PHE   A 1 340 ? 132.870 124.007 134.045 1.00 65.32  ? 366 PHE   A CB  1 
ATOM   2704 C CG  . PHE   A 1 340 ? 133.767 125.214 134.077 1.00 67.35  ? 366 PHE   A CG  1 
ATOM   2705 C CD1 . PHE   A 1 340 ? 135.140 125.071 134.160 1.00 73.08  ? 366 PHE   A CD1 1 
ATOM   2706 C CD2 . PHE   A 1 340 ? 133.239 126.491 134.018 1.00 65.07  ? 366 PHE   A CD2 1 
ATOM   2707 C CE1 . PHE   A 1 340 ? 135.965 126.178 134.188 1.00 73.64  ? 366 PHE   A CE1 1 
ATOM   2708 C CE2 . PHE   A 1 340 ? 134.061 127.598 134.047 1.00 65.95  ? 366 PHE   A CE2 1 
ATOM   2709 C CZ  . PHE   A 1 340 ? 135.423 127.442 134.131 1.00 67.77  ? 366 PHE   A CZ  1 
ATOM   2710 N N   . THR   A 1 341 ? 131.041 124.905 136.456 1.00 62.08  ? 367 THR   A N   1 
ATOM   2711 C CA  . THR   A 1 341 ? 130.652 125.937 137.414 1.00 58.84  ? 367 THR   A CA  1 
ATOM   2712 C C   . THR   A 1 341 ? 130.874 125.466 138.846 1.00 67.62  ? 367 THR   A C   1 
ATOM   2713 O O   . THR   A 1 341 ? 131.534 126.149 139.645 1.00 75.79  ? 367 THR   A O   1 
ATOM   2714 C CB  . THR   A 1 341 ? 129.190 126.327 137.200 1.00 58.21  ? 367 THR   A CB  1 
ATOM   2715 O OG1 . THR   A 1 341 ? 129.013 126.807 135.863 1.00 68.91  ? 367 THR   A OG1 1 
ATOM   2716 C CG2 . THR   A 1 341 ? 128.771 127.405 138.182 1.00 57.05  ? 367 THR   A CG2 1 
ATOM   2717 N N   . LEU   A 1 342 ? 130.353 124.282 139.181 1.00 66.86  ? 368 LEU   A N   1 
ATOM   2718 C CA  . LEU   A 1 342 ? 130.473 123.788 140.550 1.00 67.12  ? 368 LEU   A CA  1 
ATOM   2719 C C   . LEU   A 1 342 ? 131.932 123.559 140.931 1.00 67.91  ? 368 LEU   A C   1 
ATOM   2720 O O   . LEU   A 1 342 ? 132.382 123.994 142.001 1.00 73.20  ? 368 LEU   A O   1 
ATOM   2721 C CB  . LEU   A 1 342 ? 129.665 122.500 140.715 1.00 68.15  ? 368 LEU   A CB  1 
ATOM   2722 C CG  . LEU   A 1 342 ? 128.152 122.606 140.502 1.00 73.84  ? 368 LEU   A CG  1 
ATOM   2723 C CD1 . LEU   A 1 342 ? 127.515 121.230 140.555 1.00 74.58  ? 368 LEU   A CD1 1 
ATOM   2724 C CD2 . LEU   A 1 342 ? 127.512 123.526 141.528 1.00 76.29  ? 368 LEU   A CD2 1 
ATOM   2725 N N   . LEU   A 1 343 ? 132.695 122.891 140.060 1.00 62.28  ? 369 LEU   A N   1 
ATOM   2726 C CA  . LEU   A 1 343 ? 134.084 122.594 140.389 1.00 61.80  ? 369 LEU   A CA  1 
ATOM   2727 C C   . LEU   A 1 343 ? 134.912 123.866 140.511 1.00 61.10  ? 369 LEU   A C   1 
ATOM   2728 O O   . LEU   A 1 343 ? 135.752 123.978 141.410 1.00 69.06  ? 369 LEU   A O   1 
ATOM   2729 C CB  . LEU   A 1 343 ? 134.690 121.658 139.344 1.00 66.21  ? 369 LEU   A CB  1 
ATOM   2730 C CG  . LEU   A 1 343 ? 134.611 120.164 139.671 1.00 70.36  ? 369 LEU   A CG  1 
ATOM   2731 C CD1 . LEU   A 1 343 ? 133.173 119.694 139.827 1.00 71.42  ? 369 LEU   A CD1 1 
ATOM   2732 C CD2 . LEU   A 1 343 ? 135.322 119.353 138.601 1.00 68.36  ? 369 LEU   A CD2 1 
ATOM   2733 N N   . TYR   A 1 344 ? 134.694 124.835 139.621 1.00 54.58  ? 370 TYR   A N   1 
ATOM   2734 C CA  . TYR   A 1 344 ? 135.455 126.075 139.676 1.00 60.13  ? 370 TYR   A CA  1 
ATOM   2735 C C   . TYR   A 1 344 ? 135.150 126.857 140.945 1.00 63.00  ? 370 TYR   A C   1 
ATOM   2736 O O   . TYR   A 1 344 ? 136.066 127.397 141.577 1.00 69.75  ? 370 TYR   A O   1 
ATOM   2737 C CB  . TYR   A 1 344 ? 135.154 126.921 138.440 1.00 66.40  ? 370 TYR   A CB  1 
ATOM   2738 C CG  . TYR   A 1 344 ? 135.995 128.169 138.330 1.00 66.07  ? 370 TYR   A CG  1 
ATOM   2739 C CD1 . TYR   A 1 344 ? 137.269 128.122 137.789 1.00 59.41  ? 370 TYR   A CD1 1 
ATOM   2740 C CD2 . TYR   A 1 344 ? 135.512 129.395 138.759 1.00 66.99  ? 370 TYR   A CD2 1 
ATOM   2741 C CE1 . TYR   A 1 344 ? 138.039 129.256 137.684 1.00 61.02  ? 370 TYR   A CE1 1 
ATOM   2742 C CE2 . TYR   A 1 344 ? 136.276 130.535 138.657 1.00 63.24  ? 370 TYR   A CE2 1 
ATOM   2743 C CZ  . TYR   A 1 344 ? 137.538 130.459 138.119 1.00 62.93  ? 370 TYR   A CZ  1 
ATOM   2744 O OH  . TYR   A 1 344 ? 138.302 131.598 138.015 1.00 66.67  ? 370 TYR   A OH  1 
ATOM   2745 N N   . LEU   A 1 345 ? 133.874 126.943 141.333 1.00 57.82  ? 371 LEU   A N   1 
ATOM   2746 C CA  . LEU   A 1 345 ? 133.552 127.668 142.558 1.00 62.55  ? 371 LEU   A CA  1 
ATOM   2747 C C   . LEU   A 1 345 ? 134.139 126.972 143.783 1.00 68.17  ? 371 LEU   A C   1 
ATOM   2748 O O   . LEU   A 1 345 ? 134.661 127.635 144.691 1.00 71.23  ? 371 LEU   A O   1 
ATOM   2749 C CB  . LEU   A 1 345 ? 132.038 127.833 142.698 1.00 64.45  ? 371 LEU   A CB  1 
ATOM   2750 C CG  . LEU   A 1 345 ? 131.332 128.739 141.681 1.00 67.37  ? 371 LEU   A CG  1 
ATOM   2751 C CD1 . LEU   A 1 345 ? 129.837 128.764 141.953 1.00 68.97  ? 371 LEU   A CD1 1 
ATOM   2752 C CD2 . LEU   A 1 345 ? 131.890 130.153 141.690 1.00 64.77  ? 371 LEU   A CD2 1 
ATOM   2753 N N   . LEU   A 1 346 ? 134.076 125.637 143.826 1.00 66.21  ? 372 LEU   A N   1 
ATOM   2754 C CA  . LEU   A 1 346 ? 134.683 124.921 144.947 1.00 64.21  ? 372 LEU   A CA  1 
ATOM   2755 C C   . LEU   A 1 346 ? 136.193 125.138 144.990 1.00 61.51  ? 372 LEU   A C   1 
ATOM   2756 O O   . LEU   A 1 346 ? 136.771 125.324 146.069 1.00 61.57  ? 372 LEU   A O   1 
ATOM   2757 C CB  . LEU   A 1 346 ? 134.358 123.429 144.865 1.00 63.29  ? 372 LEU   A CB  1 
ATOM   2758 C CG  . LEU   A 1 346 ? 133.170 122.968 145.714 1.00 68.91  ? 372 LEU   A CG  1 
ATOM   2759 C CD1 . LEU   A 1 346 ? 131.902 123.741 145.375 1.00 66.10  ? 372 LEU   A CD1 1 
ATOM   2760 C CD2 . LEU   A 1 346 ? 132.946 121.473 145.546 1.00 71.06  ? 372 LEU   A CD2 1 
ATOM   2761 N N   . GLU   A 1 347 ? 136.848 125.123 143.827 1.00 58.15  ? 373 GLU   A N   1 
ATOM   2762 C CA  . GLU   A 1 347 ? 138.287 125.360 143.782 1.00 56.29  ? 373 GLU   A CA  1 
ATOM   2763 C C   . GLU   A 1 347 ? 138.629 126.762 144.263 1.00 57.14  ? 373 GLU   A C   1 
ATOM   2764 O O   . GLU   A 1 347 ? 139.611 126.954 144.989 1.00 65.13  ? 373 GLU   A O   1 
ATOM   2765 C CB  . GLU   A 1 347 ? 138.811 125.137 142.364 1.00 61.47  ? 373 GLU   A CB  1 
ATOM   2766 C CG  . GLU   A 1 347 ? 140.309 125.389 142.199 1.00 68.21  ? 373 GLU   A CG  1 
ATOM   2767 C CD  . GLU   A 1 347 ? 140.645 126.773 141.657 1.00 75.99  ? 373 GLU   A CD  1 
ATOM   2768 O OE1 . GLU   A 1 347 ? 139.788 127.680 141.711 1.00 75.46  ? 373 GLU   A OE1 1 
ATOM   2769 O OE2 . GLU   A 1 347 ? 141.781 126.951 141.170 1.00 79.08  ? 373 GLU   A OE2 1 
ATOM   2770 N N   . GLN   A 1 348 ? 137.848 127.760 143.847 1.00 57.07  ? 374 GLN   A N   1 
ATOM   2771 C CA  . GLN   A 1 348 ? 138.091 129.124 144.301 1.00 56.78  ? 374 GLN   A CA  1 
ATOM   2772 C C   . GLN   A 1 348 ? 137.920 129.239 145.808 1.00 64.20  ? 374 GLN   A C   1 
ATOM   2773 O O   . GLN   A 1 348 ? 138.686 129.943 146.474 1.00 68.07  ? 374 GLN   A O   1 
ATOM   2774 C CB  . GLN   A 1 348 ? 137.155 130.097 143.583 1.00 63.45  ? 374 GLN   A CB  1 
ATOM   2775 C CG  . GLN   A 1 348 ? 137.562 130.436 142.153 1.00 68.80  ? 374 GLN   A CG  1 
ATOM   2776 C CD  . GLN   A 1 348 ? 138.855 131.221 142.071 1.00 69.66  ? 374 GLN   A CD  1 
ATOM   2777 O OE1 . GLN   A 1 348 ? 139.780 130.836 141.357 1.00 71.92  ? 374 GLN   A OE1 1 
ATOM   2778 N NE2 . GLN   A 1 348 ? 138.926 132.329 142.796 1.00 69.40  ? 374 GLN   A NE2 1 
ATOM   2779 N N   . LEU   A 1 349 ? 136.910 128.567 146.366 1.00 68.66  ? 375 LEU   A N   1 
ATOM   2780 C CA  . LEU   A 1 349 ? 136.733 128.596 147.815 1.00 68.24  ? 375 LEU   A CA  1 
ATOM   2781 C C   . LEU   A 1 349 ? 137.908 127.937 148.529 1.00 66.50  ? 375 LEU   A C   1 
ATOM   2782 O O   . LEU   A 1 349 ? 138.374 128.434 149.561 1.00 65.44  ? 375 LEU   A O   1 
ATOM   2783 C CB  . LEU   A 1 349 ? 135.424 127.908 148.204 1.00 66.10  ? 375 LEU   A CB  1 
ATOM   2784 C CG  . LEU   A 1 349 ? 134.115 128.634 147.891 1.00 70.16  ? 375 LEU   A CG  1 
ATOM   2785 C CD1 . LEU   A 1 349 ? 132.934 127.725 148.172 1.00 68.59  ? 375 LEU   A CD1 1 
ATOM   2786 C CD2 . LEU   A 1 349 ? 133.993 129.917 148.694 1.00 69.43  ? 375 LEU   A CD2 1 
ATOM   2787 N N   . PHE   A 1 350 ? 138.398 126.816 148.000 1.00 60.71  ? 376 PHE   A N   1 
ATOM   2788 C CA  . PHE   A 1 350 ? 139.429 126.055 148.698 1.00 52.93  ? 376 PHE   A CA  1 
ATOM   2789 C C   . PHE   A 1 350 ? 140.819 126.670 148.576 1.00 60.41  ? 376 PHE   A C   1 
ATOM   2790 O O   . PHE   A 1 350 ? 141.608 126.576 149.523 1.00 69.75  ? 376 PHE   A O   1 
ATOM   2791 C CB  . PHE   A 1 350 ? 139.466 124.621 148.175 1.00 53.55  ? 376 PHE   A CB  1 
ATOM   2792 C CG  . PHE   A 1 350 ? 140.647 123.832 148.661 1.00 55.05  ? 376 PHE   A CG  1 
ATOM   2793 C CD1 . PHE   A 1 350 ? 140.727 123.419 149.978 1.00 62.63  ? 376 PHE   A CD1 1 
ATOM   2794 C CD2 . PHE   A 1 350 ? 141.672 123.497 147.798 1.00 56.15  ? 376 PHE   A CD2 1 
ATOM   2795 C CE1 . PHE   A 1 350 ? 141.810 122.691 150.424 1.00 64.84  ? 376 PHE   A CE1 1 
ATOM   2796 C CE2 . PHE   A 1 350 ? 142.755 122.770 148.239 1.00 64.28  ? 376 PHE   A CE2 1 
ATOM   2797 C CZ  . PHE   A 1 350 ? 142.824 122.366 149.554 1.00 65.41  ? 376 PHE   A CZ  1 
ATOM   2798 N N   . LEU   A 1 351 ? 141.143 127.281 147.432 1.00 62.24  ? 377 LEU   A N   1 
ATOM   2799 C CA  . LEU   A 1 351 ? 142.529 127.669 147.159 1.00 59.29  ? 377 LEU   A CA  1 
ATOM   2800 C C   . LEU   A 1 351 ? 143.116 128.630 148.185 1.00 58.92  ? 377 LEU   A C   1 
ATOM   2801 O O   . LEU   A 1 351 ? 144.283 128.441 148.568 1.00 62.73  ? 377 LEU   A O   1 
ATOM   2802 C CB  . LEU   A 1 351 ? 142.640 128.261 145.750 1.00 59.46  ? 377 LEU   A CB  1 
ATOM   2803 C CG  . LEU   A 1 351 ? 143.860 127.804 144.947 1.00 55.02  ? 377 LEU   A CG  1 
ATOM   2804 C CD1 . LEU   A 1 351 ? 143.872 128.478 143.591 1.00 62.50  ? 377 LEU   A CD1 1 
ATOM   2805 C CD2 . LEU   A 1 351 ? 145.148 128.088 145.690 1.00 56.30  ? 377 LEU   A CD2 1 
ATOM   2806 N N   . PRO   A 1 352 ? 142.413 129.670 148.649 1.00 54.93  ? 378 PRO   A N   1 
ATOM   2807 C CA  . PRO   A 1 352 ? 143.027 130.561 149.649 1.00 58.92  ? 378 PRO   A CA  1 
ATOM   2808 C C   . PRO   A 1 352 ? 143.407 129.867 150.945 1.00 67.81  ? 378 PRO   A C   1 
ATOM   2809 O O   . PRO   A 1 352 ? 144.312 130.342 151.642 1.00 75.08  ? 378 PRO   A O   1 
ATOM   2810 C CB  . PRO   A 1 352 ? 141.947 131.625 149.878 1.00 66.12  ? 378 PRO   A CB  1 
ATOM   2811 C CG  . PRO   A 1 352 ? 141.158 131.636 148.636 1.00 64.73  ? 378 PRO   A CG  1 
ATOM   2812 C CD  . PRO   A 1 352 ? 141.140 130.219 148.151 1.00 60.71  ? 378 PRO   A CD  1 
ATOM   2813 N N   . TYR   A 1 353 ? 142.747 128.759 151.288 1.00 65.73  ? 379 TYR   A N   1 
ATOM   2814 C CA  . TYR   A 1 353 ? 142.997 128.028 152.526 1.00 59.53  ? 379 TYR   A CA  1 
ATOM   2815 C C   . TYR   A 1 353 ? 143.739 126.719 152.280 1.00 56.90  ? 379 TYR   A C   1 
ATOM   2816 O O   . TYR   A 1 353 ? 143.630 125.782 153.072 1.00 62.90  ? 379 TYR   A O   1 
ATOM   2817 C CB  . TYR   A 1 353 ? 141.684 127.764 153.255 1.00 58.55  ? 379 TYR   A CB  1 
ATOM   2818 C CG  . TYR   A 1 353 ? 140.948 129.022 153.626 1.00 60.10  ? 379 TYR   A CG  1 
ATOM   2819 C CD1 . TYR   A 1 353 ? 141.387 129.821 154.667 1.00 64.19  ? 379 TYR   A CD1 1 
ATOM   2820 C CD2 . TYR   A 1 353 ? 139.813 129.411 152.936 1.00 63.39  ? 379 TYR   A CD2 1 
ATOM   2821 C CE1 . TYR   A 1 353 ? 140.719 130.973 155.010 1.00 66.46  ? 379 TYR   A CE1 1 
ATOM   2822 C CE2 . TYR   A 1 353 ? 139.138 130.560 153.271 1.00 68.71  ? 379 TYR   A CE2 1 
ATOM   2823 C CZ  . TYR   A 1 353 ? 139.595 131.337 154.309 1.00 71.43  ? 379 TYR   A CZ  1 
ATOM   2824 O OH  . TYR   A 1 353 ? 138.924 132.486 154.648 1.00 74.09  ? 379 TYR   A OH  1 
ATOM   2825 N N   . SER   A 1 354 ? 144.499 126.642 151.189 1.00 52.75  ? 380 SER   A N   1 
ATOM   2826 C CA  . SER   A 1 354 ? 145.302 125.472 150.872 1.00 57.38  ? 380 SER   A CA  1 
ATOM   2827 C C   . SER   A 1 354 ? 146.724 125.579 151.409 1.00 73.15  ? 380 SER   A C   1 
ATOM   2828 O O   . SER   A 1 354 ? 147.616 124.880 150.916 1.00 80.50  ? 380 SER   A O   1 
ATOM   2829 C CB  . SER   A 1 354 ? 145.334 125.257 149.359 1.00 62.67  ? 380 SER   A CB  1 
ATOM   2830 O OG  . SER   A 1 354 ? 145.991 126.330 148.709 1.00 73.51  ? 380 SER   A OG  1 
ATOM   2831 N N   . HIS   A 1 355 ? 146.956 126.435 152.406 1.00 73.43  ? 381 HIS   A N   1 
ATOM   2832 C CA  . HIS   A 1 355 ? 148.295 126.626 152.944 1.00 68.05  ? 381 HIS   A CA  1 
ATOM   2833 C C   . HIS   A 1 355 ? 148.736 125.499 153.867 1.00 68.69  ? 381 HIS   A C   1 
ATOM   2834 O O   . HIS   A 1 355 ? 149.923 125.431 154.203 1.00 72.84  ? 381 HIS   A O   1 
ATOM   2835 C CB  . HIS   A 1 355 ? 148.370 127.955 153.694 1.00 62.99  ? 381 HIS   A CB  1 
ATOM   2836 C CG  . HIS   A 1 355 ? 148.024 129.140 152.850 1.00 65.67  ? 381 HIS   A CG  1 
ATOM   2837 N ND1 . HIS   A 1 355 ? 148.712 129.458 151.700 1.00 70.31  ? 381 HIS   A ND1 1 
ATOM   2838 C CD2 . HIS   A 1 355 ? 147.064 130.084 152.988 1.00 69.72  ? 381 HIS   A CD2 1 
ATOM   2839 C CE1 . HIS   A 1 355 ? 148.190 130.546 151.165 1.00 72.42  ? 381 HIS   A CE1 1 
ATOM   2840 N NE2 . HIS   A 1 355 ? 147.190 130.948 151.928 1.00 72.03  ? 381 HIS   A NE2 1 
ATOM   2841 N N   . PHE   A 1 356 ? 147.824 124.620 154.280 1.00 69.23  ? 382 PHE   A N   1 
ATOM   2842 C CA  . PHE   A 1 356 ? 148.207 123.467 155.084 1.00 73.33  ? 382 PHE   A CA  1 
ATOM   2843 C C   . PHE   A 1 356 ? 148.797 122.335 154.253 1.00 72.57  ? 382 PHE   A C   1 
ATOM   2844 O O   . PHE   A 1 356 ? 149.326 121.382 154.833 1.00 77.30  ? 382 PHE   A O   1 
ATOM   2845 C CB  . PHE   A 1 356 ? 147.009 122.951 155.898 1.00 74.79  ? 382 PHE   A CB  1 
ATOM   2846 C CG  . PHE   A 1 356 ? 145.854 122.450 155.067 1.00 72.15  ? 382 PHE   A CG  1 
ATOM   2847 C CD1 . PHE   A 1 356 ? 144.825 123.301 154.701 1.00 73.86  ? 382 PHE   A CD1 1 
ATOM   2848 C CD2 . PHE   A 1 356 ? 145.779 121.121 154.686 1.00 73.01  ? 382 PHE   A CD2 1 
ATOM   2849 C CE1 . PHE   A 1 356 ? 143.762 122.842 153.950 1.00 77.05  ? 382 PHE   A CE1 1 
ATOM   2850 C CE2 . PHE   A 1 356 ? 144.719 120.659 153.937 1.00 73.30  ? 382 PHE   A CE2 1 
ATOM   2851 C CZ  . PHE   A 1 356 ? 143.709 121.519 153.570 1.00 76.62  ? 382 PHE   A CZ  1 
ATOM   2852 N N   . LEU   A 1 357 ? 148.729 122.417 152.923 1.00 69.28  ? 383 LEU   A N   1 
ATOM   2853 C CA  . LEU   A 1 357 ? 149.325 121.427 152.035 1.00 70.39  ? 383 LEU   A CA  1 
ATOM   2854 C C   . LEU   A 1 357 ? 150.677 121.873 151.495 1.00 73.99  ? 383 LEU   A C   1 
ATOM   2855 O O   . LEU   A 1 357 ? 151.631 121.090 151.495 1.00 81.59  ? 383 LEU   A O   1 
ATOM   2856 C CB  . LEU   A 1 357 ? 148.376 121.132 150.867 1.00 73.21  ? 383 LEU   A CB  1 
ATOM   2857 C CG  . LEU   A 1 357 ? 146.984 120.605 151.221 1.00 74.14  ? 383 LEU   A CG  1 
ATOM   2858 C CD1 . LEU   A 1 357 ? 146.145 120.465 149.965 1.00 73.39  ? 383 LEU   A CD1 1 
ATOM   2859 C CD2 . LEU   A 1 357 ? 147.068 119.276 151.956 1.00 73.86  ? 383 LEU   A CD2 1 
ATOM   2860 N N   . THR   A 1 358 ? 150.778 123.122 151.039 1.00 74.21  ? 384 THR   A N   1 
ATOM   2861 C CA  . THR   A 1 358 ? 152.025 123.672 150.510 1.00 80.38  ? 384 THR   A CA  1 
ATOM   2862 C C   . THR   A 1 358 ? 152.704 124.464 151.624 1.00 85.52  ? 384 THR   A C   1 
ATOM   2863 O O   . THR   A 1 358 ? 152.688 125.694 151.654 1.00 87.24  ? 384 THR   A O   1 
ATOM   2864 C CB  . THR   A 1 358 ? 151.753 124.538 149.286 1.00 78.26  ? 384 THR   A CB  1 
ATOM   2865 O OG1 . THR   A 1 358 ? 150.868 125.608 149.639 1.00 75.07  ? 384 THR   A OG1 1 
ATOM   2866 C CG2 . THR   A 1 358 ? 151.127 123.710 148.174 1.00 78.92  ? 384 THR   A CG2 1 
ATOM   2867 N N   . GLN   A 1 359 ? 153.316 123.731 152.555 1.00 80.80  ? 385 GLN   A N   1 
ATOM   2868 C CA  . GLN   A 1 359 ? 153.968 124.349 153.703 1.00 76.16  ? 385 GLN   A CA  1 
ATOM   2869 C C   . GLN   A 1 359 ? 155.396 124.794 153.418 1.00 71.23  ? 385 GLN   A C   1 
ATOM   2870 O O   . GLN   A 1 359 ? 155.976 125.508 154.243 1.00 74.50  ? 385 GLN   A O   1 
ATOM   2871 C CB  . GLN   A 1 359 ? 153.959 123.388 154.891 1.00 79.99  ? 385 GLN   A CB  1 
ATOM   2872 C CG  . GLN   A 1 359 ? 152.625 123.337 155.613 1.00 82.18  ? 385 GLN   A CG  1 
ATOM   2873 C CD  . GLN   A 1 359 ? 152.646 122.419 156.814 1.00 87.85  ? 385 GLN   A CD  1 
ATOM   2874 O OE1 . GLN   A 1 359 ? 153.347 121.408 156.825 1.00 90.85  ? 385 GLN   A OE1 1 
ATOM   2875 N NE2 . GLN   A 1 359 ? 151.878 122.770 157.838 1.00 85.24  ? 385 GLN   A NE2 1 
ATOM   2876 N N   . GLY   A 1 360 ? 155.979 124.394 152.289 1.00 71.55  ? 386 GLY   A N   1 
ATOM   2877 C CA  . GLY   A 1 360 ? 157.305 124.878 151.949 1.00 70.75  ? 386 GLY   A CA  1 
ATOM   2878 C C   . GLY   A 1 360 ? 157.345 126.376 151.735 1.00 69.91  ? 386 GLY   A C   1 
ATOM   2879 O O   . GLY   A 1 360 ? 158.361 127.019 152.008 1.00 73.55  ? 386 GLY   A O   1 
ATOM   2880 N N   . TYR   A 1 361 ? 156.248 126.950 151.248 1.00 72.54  ? 387 TYR   A N   1 
ATOM   2881 C CA  . TYR   A 1 361 ? 156.149 128.382 151.009 1.00 74.66  ? 387 TYR   A CA  1 
ATOM   2882 C C   . TYR   A 1 361 ? 155.667 129.158 152.229 1.00 71.78  ? 387 TYR   A C   1 
ATOM   2883 O O   . TYR   A 1 361 ? 155.628 130.391 152.180 1.00 71.46  ? 387 TYR   A O   1 
ATOM   2884 C CB  . TYR   A 1 361 ? 155.207 128.648 149.830 1.00 72.71  ? 387 TYR   A CB  1 
ATOM   2885 C CG  . TYR   A 1 361 ? 155.628 127.970 148.545 1.00 71.05  ? 387 TYR   A CG  1 
ATOM   2886 C CD1 . TYR   A 1 361 ? 156.492 128.594 147.658 1.00 67.64  ? 387 TYR   A CD1 1 
ATOM   2887 C CD2 . TYR   A 1 361 ? 155.160 126.708 148.217 1.00 70.89  ? 387 TYR   A CD2 1 
ATOM   2888 C CE1 . TYR   A 1 361 ? 156.878 127.979 146.486 1.00 66.13  ? 387 TYR   A CE1 1 
ATOM   2889 C CE2 . TYR   A 1 361 ? 155.542 126.087 147.046 1.00 69.37  ? 387 TYR   A CE2 1 
ATOM   2890 C CZ  . TYR   A 1 361 ? 156.401 126.727 146.186 1.00 66.06  ? 387 TYR   A CZ  1 
ATOM   2891 O OH  . TYR   A 1 361 ? 156.783 126.112 145.017 1.00 71.32  ? 387 TYR   A OH  1 
ATOM   2892 N N   . ASN   A 1 362 ? 155.302 128.480 153.313 1.00 71.55  ? 388 ASN   A N   1 
ATOM   2893 C CA  . ASN   A 1 362 ? 154.845 129.178 154.505 1.00 70.38  ? 388 ASN   A CA  1 
ATOM   2894 C C   . ASN   A 1 362 ? 155.991 129.933 155.169 1.00 68.15  ? 388 ASN   A C   1 
ATOM   2895 O O   . ASN   A 1 362 ? 157.158 129.541 155.094 1.00 64.81  ? 388 ASN   A O   1 
ATOM   2896 C CB  . ASN   A 1 362 ? 154.225 128.200 155.503 1.00 71.78  ? 388 ASN   A CB  1 
ATOM   2897 C CG  . ASN   A 1 362 ? 152.726 128.068 155.338 1.00 71.48  ? 388 ASN   A CG  1 
ATOM   2898 O OD1 . ASN   A 1 362 ? 152.220 127.008 154.982 1.00 77.42  ? 388 ASN   A OD1 1 
ATOM   2899 N ND2 . ASN   A 1 362 ? 152.006 129.147 155.606 1.00 72.16  ? 388 ASN   A ND2 1 
ATOM   2900 N N   . ASN   A 1 363 ? 155.634 131.027 155.827 1.00 67.78  ? 389 ASN   A N   1 
ATOM   2901 C CA  . ASN   A 1 363 ? 156.564 131.928 156.498 1.00 61.52  ? 389 ASN   A CA  1 
ATOM   2902 C C   . ASN   A 1 363 ? 155.816 132.521 157.688 1.00 66.18  ? 389 ASN   A C   1 
ATOM   2903 O O   . ASN   A 1 363 ? 154.848 131.928 158.176 1.00 71.02  ? 389 ASN   A O   1 
ATOM   2904 C CB  . ASN   A 1 363 ? 157.102 132.984 155.512 1.00 58.45  ? 389 ASN   A CB  1 
ATOM   2905 C CG  . ASN   A 1 363 ? 157.972 132.382 154.433 1.00 63.31  ? 389 ASN   A CG  1 
ATOM   2906 O OD1 . ASN   A 1 363 ? 157.655 132.463 153.247 1.00 72.10  ? 389 ASN   A OD1 1 
ATOM   2907 N ND2 . ASN   A 1 363 ? 159.076 131.771 154.839 1.00 67.64  ? 389 ASN   A ND2 1 
ATOM   2908 N N   . TRP   A 1 364 ? 156.298 133.657 158.200 1.00 62.35  ? 390 TRP   A N   1 
ATOM   2909 C CA  . TRP   A 1 364 ? 155.523 134.417 159.176 1.00 64.90  ? 390 TRP   A CA  1 
ATOM   2910 C C   . TRP   A 1 364 ? 154.107 134.667 158.673 1.00 67.87  ? 390 TRP   A C   1 
ATOM   2911 O O   . TRP   A 1 364 ? 153.139 134.548 159.434 1.00 70.99  ? 390 TRP   A O   1 
ATOM   2912 C CB  . TRP   A 1 364 ? 156.212 135.749 159.475 1.00 69.00  ? 390 TRP   A CB  1 
ATOM   2913 C CG  . TRP   A 1 364 ? 157.540 135.636 160.166 1.00 66.51  ? 390 TRP   A CG  1 
ATOM   2914 C CD1 . TRP   A 1 364 ? 158.139 134.500 160.628 1.00 64.17  ? 390 TRP   A CD1 1 
ATOM   2915 C CD2 . TRP   A 1 364 ? 158.433 136.710 160.471 1.00 58.82  ? 390 TRP   A CD2 1 
ATOM   2916 N NE1 . TRP   A 1 364 ? 159.347 134.803 161.201 1.00 64.56  ? 390 TRP   A NE1 1 
ATOM   2917 C CE2 . TRP   A 1 364 ? 159.549 136.155 161.119 1.00 62.08  ? 390 TRP   A CE2 1 
ATOM   2918 C CE3 . TRP   A 1 364 ? 158.393 138.089 160.262 1.00 58.52  ? 390 TRP   A CE3 1 
ATOM   2919 C CZ2 . TRP   A 1 364 ? 160.615 136.930 161.557 1.00 64.64  ? 390 TRP   A CZ2 1 
ATOM   2920 C CZ3 . TRP   A 1 364 ? 159.448 138.855 160.696 1.00 60.23  ? 390 TRP   A CZ3 1 
ATOM   2921 C CH2 . TRP   A 1 364 ? 160.547 138.276 161.335 1.00 63.49  ? 390 TRP   A CH2 1 
ATOM   2922 N N   . THR   A 1 365 ? 153.968 135.014 157.397 1.00 68.86  ? 391 THR   A N   1 
ATOM   2923 C CA  . THR   A 1 365 ? 152.669 135.104 156.750 1.00 73.94  ? 391 THR   A CA  1 
ATOM   2924 C C   . THR   A 1 365 ? 152.288 133.723 156.220 1.00 71.23  ? 391 THR   A C   1 
ATOM   2925 O O   . THR   A 1 365 ? 152.989 132.734 156.448 1.00 73.89  ? 391 THR   A O   1 
ATOM   2926 C CB  . THR   A 1 365 ? 152.693 136.155 155.640 1.00 79.21  ? 391 THR   A CB  1 
ATOM   2927 O OG1 . THR   A 1 365 ? 151.353 136.443 155.224 1.00 82.44  ? 391 THR   A OG1 1 
ATOM   2928 C CG2 . THR   A 1 365 ? 153.496 135.665 154.435 1.00 78.96  ? 391 THR   A CG2 1 
ATOM   2929 N N   . ASN   A 1 366 ? 151.173 133.644 155.500 1.00 69.81  ? 392 ASN   A N   1 
ATOM   2930 C CA  . ASN   A 1 366 ? 150.650 132.390 154.971 1.00 71.55  ? 392 ASN   A CA  1 
ATOM   2931 C C   . ASN   A 1 366 ? 150.838 132.361 153.461 1.00 79.12  ? 392 ASN   A C   1 
ATOM   2932 O O   . ASN   A 1 366 ? 150.208 133.140 152.737 1.00 86.37  ? 392 ASN   A O   1 
ATOM   2933 C CB  . ASN   A 1 366 ? 149.175 132.223 155.330 1.00 80.01  ? 392 ASN   A CB  1 
ATOM   2934 C CG  . ASN   A 1 366 ? 148.965 131.906 156.795 1.00 86.92  ? 392 ASN   A CG  1 
ATOM   2935 O OD1 . ASN   A 1 366 ? 149.755 131.188 157.406 1.00 84.32  ? 392 ASN   A OD1 1 
ATOM   2936 N ND2 . ASN   A 1 366 ? 147.893 132.441 157.369 1.00 92.43  ? 392 ASN   A ND2 1 
ATOM   2937 N N   . GLY   A 1 367 ? 151.701 131.462 152.993 1.00 76.94  ? 393 GLY   A N   1 
ATOM   2938 C CA  . GLY   A 1 367 ? 151.875 131.218 151.575 1.00 72.44  ? 393 GLY   A CA  1 
ATOM   2939 C C   . GLY   A 1 367 ? 152.348 132.413 150.775 1.00 66.40  ? 393 GLY   A C   1 
ATOM   2940 O O   . GLY   A 1 367 ? 152.572 133.495 151.323 1.00 66.19  ? 393 GLY   A O   1 
ATOM   2941 N N   . LEU   A 1 368 ? 152.497 132.222 149.467 1.00 64.59  ? 394 LEU   A N   1 
ATOM   2942 C CA  . LEU   A 1 368 ? 152.915 133.300 148.590 1.00 65.43  ? 394 LEU   A CA  1 
ATOM   2943 C C   . LEU   A 1 368 ? 151.839 134.378 148.526 1.00 67.53  ? 394 LEU   A C   1 
ATOM   2944 O O   . LEU   A 1 368 ? 150.679 134.162 148.885 1.00 75.08  ? 394 LEU   A O   1 
ATOM   2945 C CB  . LEU   A 1 368 ? 153.188 132.777 147.179 1.00 65.09  ? 394 LEU   A CB  1 
ATOM   2946 C CG  . LEU   A 1 368 ? 154.363 131.821 146.977 1.00 67.48  ? 394 LEU   A CG  1 
ATOM   2947 C CD1 . LEU   A 1 368 ? 154.289 131.192 145.598 1.00 64.68  ? 394 LEU   A CD1 1 
ATOM   2948 C CD2 . LEU   A 1 368 ? 155.684 132.542 147.161 1.00 70.48  ? 394 LEU   A CD2 1 
ATOM   2949 N N   . TYR   A 1 369 ? 152.243 135.553 148.060 1.00 62.29  ? 395 TYR   A N   1 
ATOM   2950 C CA  . TYR   A 1 369 ? 151.324 136.658 147.853 1.00 61.44  ? 395 TYR   A CA  1 
ATOM   2951 C C   . TYR   A 1 369 ? 150.678 136.538 146.480 1.00 70.41  ? 395 TYR   A C   1 
ATOM   2952 O O   . TYR   A 1 369 ? 151.353 136.237 145.491 1.00 70.43  ? 395 TYR   A O   1 
ATOM   2953 C CB  . TYR   A 1 369 ? 152.062 137.989 147.979 1.00 59.52  ? 395 TYR   A CB  1 
ATOM   2954 C CG  . TYR   A 1 369 ? 151.169 139.205 147.945 1.00 61.82  ? 395 TYR   A CG  1 
ATOM   2955 C CD1 . TYR   A 1 369 ? 150.441 139.586 149.061 1.00 63.12  ? 395 TYR   A CD1 1 
ATOM   2956 C CD2 . TYR   A 1 369 ? 151.067 139.983 146.802 1.00 75.31  ? 395 TYR   A CD2 1 
ATOM   2957 C CE1 . TYR   A 1 369 ? 149.626 140.699 149.037 1.00 71.35  ? 395 TYR   A CE1 1 
ATOM   2958 C CE2 . TYR   A 1 369 ? 150.255 141.099 146.770 1.00 81.49  ? 395 TYR   A CE2 1 
ATOM   2959 C CZ  . TYR   A 1 369 ? 149.538 141.452 147.891 1.00 81.20  ? 395 TYR   A CZ  1 
ATOM   2960 O OH  . TYR   A 1 369 ? 148.727 142.563 147.865 1.00 83.94  ? 395 TYR   A OH  1 
ATOM   2961 N N   . GLY   A 1 370 ? 149.366 136.769 146.428 1.00 75.32  ? 396 GLY   A N   1 
ATOM   2962 C CA  . GLY   A 1 370 ? 148.651 136.862 145.168 1.00 70.92  ? 396 GLY   A CA  1 
ATOM   2963 C C   . GLY   A 1 370 ? 147.318 136.145 145.098 1.00 77.01  ? 396 GLY   A C   1 
ATOM   2964 O O   . GLY   A 1 370 ? 146.416 136.617 144.399 1.00 81.44  ? 396 GLY   A O   1 
ATOM   2965 N N   . TYR   A 1 371 ? 147.164 135.024 145.811 1.00 72.84  ? 397 TYR   A N   1 
ATOM   2966 C CA  . TYR   A 1 371 ? 145.987 134.169 145.679 1.00 70.22  ? 397 TYR   A CA  1 
ATOM   2967 C C   . TYR   A 1 371 ? 145.248 133.971 146.998 1.00 65.04  ? 397 TYR   A C   1 
ATOM   2968 O O   . TYR   A 1 371 ? 144.543 132.970 147.157 1.00 70.75  ? 397 TYR   A O   1 
ATOM   2969 C CB  . TYR   A 1 371 ? 146.378 132.815 145.082 1.00 73.00  ? 397 TYR   A CB  1 
ATOM   2970 C CG  . TYR   A 1 371 ? 147.339 131.990 145.914 1.00 71.42  ? 397 TYR   A CG  1 
ATOM   2971 C CD1 . TYR   A 1 371 ? 146.874 131.092 146.865 1.00 76.30  ? 397 TYR   A CD1 1 
ATOM   2972 C CD2 . TYR   A 1 371 ? 148.708 132.086 145.726 1.00 68.21  ? 397 TYR   A CD2 1 
ATOM   2973 C CE1 . TYR   A 1 371 ? 147.743 130.333 147.616 1.00 72.66  ? 397 TYR   A CE1 1 
ATOM   2974 C CE2 . TYR   A 1 371 ? 149.584 131.327 146.474 1.00 70.32  ? 397 TYR   A CE2 1 
ATOM   2975 C CZ  . TYR   A 1 371 ? 149.095 130.451 147.416 1.00 71.01  ? 397 TYR   A CZ  1 
ATOM   2976 O OH  . TYR   A 1 371 ? 149.964 129.693 148.164 1.00 78.60  ? 397 TYR   A OH  1 
ATOM   2977 N N   . SER   A 1 372 ? 145.377 134.910 147.940 1.00 64.77  ? 398 SER   A N   1 
ATOM   2978 C CA  . SER   A 1 372 ? 144.694 134.839 149.224 1.00 72.72  ? 398 SER   A CA  1 
ATOM   2979 C C   . SER   A 1 372 ? 143.742 135.998 149.480 1.00 71.17  ? 398 SER   A C   1 
ATOM   2980 O O   . SER   A 1 372 ? 142.993 135.948 150.461 1.00 76.05  ? 398 SER   A O   1 
ATOM   2981 C CB  . SER   A 1 372 ? 145.717 134.782 150.369 1.00 77.58  ? 398 SER   A CB  1 
ATOM   2982 O OG  . SER   A 1 372 ? 146.519 133.618 150.276 1.00 81.69  ? 398 SER   A OG  1 
ATOM   2983 N N   . TRP   A 1 373 ? 143.752 137.035 148.644 1.00 68.02  ? 399 TRP   A N   1 
ATOM   2984 C CA  . TRP   A 1 373 ? 142.883 138.199 148.791 1.00 71.29  ? 399 TRP   A CA  1 
ATOM   2985 C C   . TRP   A 1 373 ? 143.135 138.953 150.093 1.00 77.94  ? 399 TRP   A C   1 
ATOM   2986 O O   . TRP   A 1 373 ? 142.255 139.676 150.571 1.00 81.83  ? 399 TRP   A O   1 
ATOM   2987 C CB  . TRP   A 1 373 ? 141.404 137.807 148.691 1.00 67.47  ? 399 TRP   A CB  1 
ATOM   2988 C CG  . TRP   A 1 373 ? 141.092 136.922 147.522 1.00 68.59  ? 399 TRP   A CG  1 
ATOM   2989 C CD1 . TRP   A 1 373 ? 140.621 135.644 147.564 1.00 72.29  ? 399 TRP   A CD1 1 
ATOM   2990 C CD2 . TRP   A 1 373 ? 141.235 137.249 146.136 1.00 65.25  ? 399 TRP   A CD2 1 
ATOM   2991 N NE1 . TRP   A 1 373 ? 140.459 135.156 146.292 1.00 68.47  ? 399 TRP   A NE1 1 
ATOM   2992 C CE2 . TRP   A 1 373 ? 140.830 136.123 145.397 1.00 62.94  ? 399 TRP   A CE2 1 
ATOM   2993 C CE3 . TRP   A 1 373 ? 141.666 138.385 145.449 1.00 70.03  ? 399 TRP   A CE3 1 
ATOM   2994 C CZ2 . TRP   A 1 373 ? 140.844 136.100 144.008 1.00 68.20  ? 399 TRP   A CZ2 1 
ATOM   2995 C CZ3 . TRP   A 1 373 ? 141.679 138.360 144.072 1.00 68.19  ? 399 TRP   A CZ3 1 
ATOM   2996 C CH2 . TRP   A 1 373 ? 141.272 137.226 143.365 1.00 68.78  ? 399 TRP   A CH2 1 
ATOM   2997 N N   . ASP   A 1 374 ? 144.327 138.805 150.675 1.00 80.60  ? 400 ASP   A N   1 
ATOM   2998 C CA  . ASP   A 1 374 ? 144.707 139.539 151.886 1.00 78.11  ? 400 ASP   A CA  1 
ATOM   2999 C C   . ASP   A 1 374 ? 145.393 140.844 151.480 1.00 78.91  ? 400 ASP   A C   1 
ATOM   3000 O O   . ASP   A 1 374 ? 146.605 141.027 151.594 1.00 78.94  ? 400 ASP   A O   1 
ATOM   3001 C CB  . ASP   A 1 374 ? 145.590 138.681 152.788 1.00 75.78  ? 400 ASP   A CB  1 
ATOM   3002 C CG  . ASP   A 1 374 ? 146.824 138.145 152.083 1.00 76.63  ? 400 ASP   A CG  1 
ATOM   3003 O OD1 . ASP   A 1 374 ? 146.971 138.386 150.867 1.00 79.91  ? 400 ASP   A OD1 1 
ATOM   3004 O OD2 . ASP   A 1 374 ? 147.646 137.480 152.748 1.00 69.52  ? 400 ASP   A OD2 1 
ATOM   3005 N N   . MET   A 1 375 ? 144.570 141.772 151.002 1.00 81.93  ? 401 MET   A N   1 
ATOM   3006 C CA  . MET   A 1 375 ? 145.053 143.013 150.413 1.00 84.69  ? 401 MET   A CA  1 
ATOM   3007 C C   . MET   A 1 375 ? 145.275 144.047 151.509 1.00 88.63  ? 401 MET   A C   1 
ATOM   3008 O O   . MET   A 1 375 ? 144.345 144.381 152.252 1.00 93.56  ? 401 MET   A O   1 
ATOM   3009 C CB  . MET   A 1 375 ? 144.054 143.545 149.387 1.00 89.01  ? 401 MET   A CB  1 
ATOM   3010 C CG  . MET   A 1 375 ? 143.707 142.572 148.272 1.00 85.80  ? 401 MET   A CG  1 
ATOM   3011 S SD  . MET   A 1 375 ? 142.441 143.229 147.172 1.00 101.02 ? 401 MET   A SD  1 
ATOM   3012 C CE  . MET   A 1 375 ? 142.197 141.839 146.073 1.00 84.15  ? 401 MET   A CE  1 
ATOM   3013 N N   . MET   A 1 376 ? 146.504 144.555 151.601 1.00 85.86  ? 402 MET   A N   1 
ATOM   3014 C CA  . MET   A 1 376 ? 146.837 145.670 152.486 1.00 84.37  ? 402 MET   A CA  1 
ATOM   3015 C C   . MET   A 1 376 ? 146.557 145.323 153.949 1.00 85.77  ? 402 MET   A C   1 
ATOM   3016 O O   . MET   A 1 376 ? 145.946 146.099 154.686 1.00 88.49  ? 402 MET   A O   1 
ATOM   3017 C CB  . MET   A 1 376 ? 146.080 146.934 152.072 1.00 92.55  ? 402 MET   A CB  1 
ATOM   3018 C CG  . MET   A 1 376 ? 146.286 147.352 150.619 1.00 99.73  ? 402 MET   A CG  1 
ATOM   3019 S SD  . MET   A 1 376 ? 147.999 147.756 150.222 1.00 119.09 ? 402 MET   A SD  1 
ATOM   3020 C CE  . MET   A 1 376 ? 147.858 148.169 148.484 1.00 105.43 ? 402 MET   A CE  1 
ATOM   3021 N N   . VAL   A 1 377 ? 147.017 144.143 154.362 1.00 82.82  ? 403 VAL   A N   1 
ATOM   3022 C CA  . VAL   A 1 377 ? 146.848 143.665 155.732 1.00 77.17  ? 403 VAL   A CA  1 
ATOM   3023 C C   . VAL   A 1 377 ? 148.172 143.483 156.458 1.00 83.05  ? 403 VAL   A C   1 
ATOM   3024 O O   . VAL   A 1 377 ? 148.170 143.397 157.696 1.00 84.64  ? 403 VAL   A O   1 
ATOM   3025 C CB  . VAL   A 1 377 ? 146.046 142.343 155.767 1.00 74.65  ? 403 VAL   A CB  1 
ATOM   3026 C CG1 . VAL   A 1 377 ? 145.592 142.013 157.187 1.00 74.57  ? 403 VAL   A CG1 1 
ATOM   3027 C CG2 . VAL   A 1 377 ? 144.856 142.418 154.814 1.00 83.04  ? 403 VAL   A CG2 1 
ATOM   3028 N N   . HIS   A 1 378 ? 149.299 143.443 155.746 1.00 82.37  ? 404 HIS   A N   1 
ATOM   3029 C CA  . HIS   A 1 378 ? 150.621 143.305 156.340 1.00 72.78  ? 404 HIS   A CA  1 
ATOM   3030 C C   . HIS   A 1 378 ? 151.527 144.404 155.811 1.00 69.13  ? 404 HIS   A C   1 
ATOM   3031 O O   . HIS   A 1 378 ? 151.555 144.672 154.606 1.00 72.30  ? 404 HIS   A O   1 
ATOM   3032 C CB  . HIS   A 1 378 ? 151.243 141.938 156.025 1.00 74.44  ? 404 HIS   A CB  1 
ATOM   3033 C CG  . HIS   A 1 378 ? 150.625 140.795 156.768 1.00 76.66  ? 404 HIS   A CG  1 
ATOM   3034 N ND1 . HIS   A 1 378 ? 149.668 140.963 157.746 1.00 78.68  ? 404 HIS   A ND1 1 
ATOM   3035 C CD2 . HIS   A 1 378 ? 150.836 139.460 156.676 1.00 77.08  ? 404 HIS   A CD2 1 
ATOM   3036 C CE1 . HIS   A 1 378 ? 149.315 139.783 158.222 1.00 80.12  ? 404 HIS   A CE1 1 
ATOM   3037 N NE2 . HIS   A 1 378 ? 150.009 138.854 157.589 1.00 78.27  ? 404 HIS   A NE2 1 
ATOM   3038 N N   . SER   A 1 379 ? 152.262 145.035 156.722 1.00 68.28  ? 405 SER   A N   1 
ATOM   3039 C CA  . SER   A 1 379 ? 153.273 146.028 156.392 1.00 73.47  ? 405 SER   A CA  1 
ATOM   3040 C C   . SER   A 1 379 ? 154.573 145.622 157.064 1.00 72.11  ? 405 SER   A C   1 
ATOM   3041 O O   . SER   A 1 379 ? 154.566 145.181 158.216 1.00 73.87  ? 405 SER   A O   1 
ATOM   3042 C CB  . SER   A 1 379 ? 152.853 147.427 156.851 1.00 78.70  ? 405 SER   A CB  1 
ATOM   3043 O OG  . SER   A 1 379 ? 151.623 147.807 156.258 1.00 85.41  ? 405 SER   A OG  1 
ATOM   3044 N N   . ARG   A 1 380 ? 155.685 145.774 156.343 1.00 63.73  ? 406 ARG   A N   1 
ATOM   3045 C CA  . ARG   A 1 380 ? 156.991 145.321 156.802 1.00 58.97  ? 406 ARG   A CA  1 
ATOM   3046 C C   . ARG   A 1 380 ? 157.996 146.457 156.698 1.00 61.68  ? 406 ARG   A C   1 
ATOM   3047 O O   . ARG   A 1 380 ? 157.905 147.306 155.807 1.00 71.31  ? 406 ARG   A O   1 
ATOM   3048 C CB  . ARG   A 1 380 ? 157.485 144.120 155.990 1.00 62.77  ? 406 ARG   A CB  1 
ATOM   3049 C CG  . ARG   A 1 380 ? 156.403 143.112 155.662 1.00 64.26  ? 406 ARG   A CG  1 
ATOM   3050 C CD  . ARG   A 1 380 ? 156.958 141.708 155.563 1.00 64.70  ? 406 ARG   A CD  1 
ATOM   3051 N NE  . ARG   A 1 380 ? 155.940 140.754 155.140 1.00 70.66  ? 406 ARG   A NE  1 
ATOM   3052 C CZ  . ARG   A 1 380 ? 156.062 139.435 155.203 1.00 76.78  ? 406 ARG   A CZ  1 
ATOM   3053 N NH1 . ARG   A 1 380 ? 157.149 138.857 155.691 1.00 76.54  ? 406 ARG   A NH1 1 
ATOM   3054 N NH2 . ARG   A 1 380 ? 155.064 138.672 154.769 1.00 81.33  ? 406 ARG   A NH2 1 
ATOM   3055 N N   . SER   A 1 381 ? 158.956 146.466 157.626 1.00 58.29  ? 407 SER   A N   1 
ATOM   3056 C CA  . SER   A 1 381 ? 160.010 147.484 157.656 1.00 56.70  ? 407 SER   A CA  1 
ATOM   3057 C C   . SER   A 1 381 ? 161.346 146.786 157.891 1.00 57.87  ? 407 SER   A C   1 
ATOM   3058 O O   . SER   A 1 381 ? 161.638 146.358 159.011 1.00 59.92  ? 407 SER   A O   1 
ATOM   3059 C CB  . SER   A 1 381 ? 159.743 148.527 158.732 1.00 63.73  ? 407 SER   A CB  1 
ATOM   3060 O OG  . SER   A 1 381 ? 160.812 149.452 158.811 1.00 65.99  ? 407 SER   A OG  1 
ATOM   3061 N N   . HIS   A 1 382 ? 162.150 146.678 156.837 1.00 54.23  ? 408 HIS   A N   1 
ATOM   3062 C CA  . HIS   A 1 382 ? 163.460 146.050 156.941 1.00 55.63  ? 408 HIS   A CA  1 
ATOM   3063 C C   . HIS   A 1 382 ? 164.492 147.049 157.442 1.00 57.34  ? 408 HIS   A C   1 
ATOM   3064 O O   . HIS   A 1 382 ? 164.473 148.224 157.062 1.00 63.75  ? 408 HIS   A O   1 
ATOM   3065 C CB  . HIS   A 1 382 ? 163.896 145.491 155.589 1.00 57.18  ? 408 HIS   A CB  1 
ATOM   3066 C CG  . HIS   A 1 382 ? 162.902 144.560 154.973 1.00 54.01  ? 408 HIS   A CG  1 
ATOM   3067 N ND1 . HIS   A 1 382 ? 161.782 145.004 154.305 1.00 52.42  ? 408 HIS   A ND1 1 
ATOM   3068 C CD2 . HIS   A 1 382 ? 162.857 143.209 154.925 1.00 58.52  ? 408 HIS   A CD2 1 
ATOM   3069 C CE1 . HIS   A 1 382 ? 161.091 143.966 153.871 1.00 57.99  ? 408 HIS   A CE1 1 
ATOM   3070 N NE2 . HIS   A 1 382 ? 161.722 142.865 154.234 1.00 63.90  ? 408 HIS   A NE2 1 
ATOM   3071 N N   . GLN   A 1 383 ? 165.395 146.572 158.296 1.00 54.55  ? 409 GLN   A N   1 
ATOM   3072 C CA  . GLN   A 1 383 ? 166.441 147.395 158.895 1.00 49.55  ? 409 GLN   A CA  1 
ATOM   3073 C C   . GLN   A 1 383 ? 167.826 147.111 158.341 1.00 48.57  ? 409 GLN   A C   1 
ATOM   3074 O O   . GLN   A 1 383 ? 168.614 148.043 158.173 1.00 57.25  ? 409 GLN   A O   1 
ATOM   3075 C CB  . GLN   A 1 383 ? 166.455 147.195 160.418 1.00 52.50  ? 409 GLN   A CB  1 
ATOM   3076 C CG  . GLN   A 1 383 ? 167.470 148.045 161.190 1.00 53.67  ? 409 GLN   A CG  1 
ATOM   3077 C CD  . GLN   A 1 383 ? 167.269 149.534 160.997 1.00 56.68  ? 409 GLN   A CD  1 
ATOM   3078 O OE1 . GLN   A 1 383 ? 166.187 149.982 160.622 1.00 61.90  ? 409 GLN   A OE1 1 
ATOM   3079 N NE2 . GLN   A 1 383 ? 168.314 150.311 161.253 1.00 54.36  ? 409 GLN   A NE2 1 
ATOM   3080 N N   . HIS   A 1 384 ? 168.153 145.854 158.056 1.00 47.50  ? 410 HIS   A N   1 
ATOM   3081 C CA  . HIS   A 1 384 ? 169.489 145.514 157.589 1.00 47.32  ? 410 HIS   A CA  1 
ATOM   3082 C C   . HIS   A 1 384 ? 169.442 144.173 156.874 1.00 54.22  ? 410 HIS   A C   1 
ATOM   3083 O O   . HIS   A 1 384 ? 168.596 143.326 157.171 1.00 62.65  ? 410 HIS   A O   1 
ATOM   3084 C CB  . HIS   A 1 384 ? 170.479 145.463 158.755 1.00 48.75  ? 410 HIS   A CB  1 
ATOM   3085 C CG  . HIS   A 1 384 ? 171.913 145.468 158.332 1.00 48.73  ? 410 HIS   A CG  1 
ATOM   3086 N ND1 . HIS   A 1 384 ? 172.494 146.542 157.694 1.00 47.76  ? 410 HIS   A ND1 1 
ATOM   3087 C CD2 . HIS   A 1 384 ? 172.884 144.535 158.458 1.00 53.79  ? 410 HIS   A CD2 1 
ATOM   3088 C CE1 . HIS   A 1 384 ? 173.761 146.270 157.444 1.00 51.41  ? 410 HIS   A CE1 1 
ATOM   3089 N NE2 . HIS   A 1 384 ? 174.023 145.058 157.899 1.00 58.73  ? 410 HIS   A NE2 1 
ATOM   3090 N N   . VAL   A 1 385 ? 170.362 143.993 155.926 1.00 51.86  ? 411 VAL   A N   1 
ATOM   3091 C CA  . VAL   A 1 385 ? 170.513 142.742 155.187 1.00 48.14  ? 411 VAL   A CA  1 
ATOM   3092 C C   . VAL   A 1 385 ? 171.998 142.529 154.934 1.00 53.20  ? 411 VAL   A C   1 
ATOM   3093 O O   . VAL   A 1 385 ? 172.628 143.334 154.240 1.00 65.24  ? 411 VAL   A O   1 
ATOM   3094 C CB  . VAL   A 1 385 ? 169.748 142.746 153.852 1.00 55.09  ? 411 VAL   A CB  1 
ATOM   3095 C CG1 . VAL   A 1 385 ? 169.931 141.411 153.137 1.00 61.14  ? 411 VAL   A CG1 1 
ATOM   3096 C CG2 . VAL   A 1 385 ? 168.268 143.057 154.064 1.00 57.60  ? 411 VAL   A CG2 1 
ATOM   3097 N N   . LYS   A 1 386 ? 172.555 141.453 155.487 1.00 50.77  ? 412 LYS   A N   1 
ATOM   3098 C CA  . LYS   A 1 386 ? 173.969 141.127 155.347 1.00 50.31  ? 412 LYS   A CA  1 
ATOM   3099 C C   . LYS   A 1 386 ? 174.114 139.782 154.654 1.00 52.34  ? 412 LYS   A C   1 
ATOM   3100 O O   . LYS   A 1 386 ? 173.476 138.803 155.055 1.00 61.27  ? 412 LYS   A O   1 
ATOM   3101 C CB  . LYS   A 1 386 ? 174.668 141.089 156.707 1.00 48.97  ? 412 LYS   A CB  1 
ATOM   3102 C CG  . LYS   A 1 386 ? 176.177 141.173 156.601 1.00 52.77  ? 412 LYS   A CG  1 
ATOM   3103 C CD  . LYS   A 1 386 ? 176.857 141.191 157.957 1.00 52.49  ? 412 LYS   A CD  1 
ATOM   3104 C CE  . LYS   A 1 386 ? 176.871 139.824 158.605 1.00 51.02  ? 412 LYS   A CE  1 
ATOM   3105 N NZ  . LYS   A 1 386 ? 177.740 139.802 159.810 1.00 54.24  ? 412 LYS   A NZ  1 
ATOM   3106 N N   . ILE   A 1 387 ? 174.946 139.741 153.616 1.00 48.99  ? 413 ILE   A N   1 
ATOM   3107 C CA  . ILE   A 1 387 ? 175.265 138.517 152.887 1.00 47.11  ? 413 ILE   A CA  1 
ATOM   3108 C C   . ILE   A 1 387 ? 176.751 138.260 153.073 1.00 48.54  ? 413 ILE   A C   1 
ATOM   3109 O O   . ILE   A 1 387 ? 177.584 139.045 152.602 1.00 54.38  ? 413 ILE   A O   1 
ATOM   3110 C CB  . ILE   A 1 387 ? 174.912 138.612 151.391 1.00 52.00  ? 413 ILE   A CB  1 
ATOM   3111 C CG1 . ILE   A 1 387 ? 173.437 138.989 151.190 1.00 56.93  ? 413 ILE   A CG1 1 
ATOM   3112 C CG2 . ILE   A 1 387 ? 175.217 137.275 150.695 1.00 53.20  ? 413 ILE   A CG2 1 
ATOM   3113 C CD1 . ILE   A 1 387 ? 173.074 139.351 149.765 1.00 57.12  ? 413 ILE   A CD1 1 
ATOM   3114 N N   . THR   A 1 388 ? 177.080 137.164 153.749 1.00 48.00  ? 414 THR   A N   1 
ATOM   3115 C CA  . THR   A 1 388 ? 178.453 136.740 153.974 1.00 46.12  ? 414 THR   A CA  1 
ATOM   3116 C C   . THR   A 1 388 ? 178.732 135.497 153.144 1.00 51.46  ? 414 THR   A C   1 
ATOM   3117 O O   . THR   A 1 388 ? 177.848 134.654 152.965 1.00 57.75  ? 414 THR   A O   1 
ATOM   3118 C CB  . THR   A 1 388 ? 178.704 136.444 155.454 1.00 48.30  ? 414 THR   A CB  1 
ATOM   3119 O OG1 . THR   A 1 388 ? 178.292 137.564 156.245 1.00 59.11  ? 414 THR   A OG1 1 
ATOM   3120 C CG2 . THR   A 1 388 ? 180.174 136.167 155.707 1.00 53.34  ? 414 THR   A CG2 1 
ATOM   3121 N N   . TYR   A 1 389 ? 179.958 135.391 152.635 1.00 52.68  ? 415 TYR   A N   1 
ATOM   3122 C CA  . TYR   A 1 389 ? 180.381 134.240 151.851 1.00 59.79  ? 415 TYR   A CA  1 
ATOM   3123 C C   . TYR   A 1 389 ? 181.759 133.781 152.302 1.00 62.21  ? 415 TYR   A C   1 
ATOM   3124 O O   . TYR   A 1 389 ? 182.642 134.601 152.575 1.00 66.51  ? 415 TYR   A O   1 
ATOM   3125 C CB  . TYR   A 1 389 ? 180.385 134.553 150.345 1.00 62.95  ? 415 TYR   A CB  1 
ATOM   3126 C CG  . TYR   A 1 389 ? 181.529 135.414 149.858 1.00 57.70  ? 415 TYR   A CG  1 
ATOM   3127 C CD1 . TYR   A 1 389 ? 181.443 136.796 149.884 1.00 58.93  ? 415 TYR   A CD1 1 
ATOM   3128 C CD2 . TYR   A 1 389 ? 182.682 134.843 149.341 1.00 60.26  ? 415 TYR   A CD2 1 
ATOM   3129 C CE1 . TYR   A 1 389 ? 182.478 137.583 149.427 1.00 63.49  ? 415 TYR   A CE1 1 
ATOM   3130 C CE2 . TYR   A 1 389 ? 183.721 135.621 148.885 1.00 63.13  ? 415 TYR   A CE2 1 
ATOM   3131 C CZ  . TYR   A 1 389 ? 183.615 136.990 148.930 1.00 63.78  ? 415 TYR   A CZ  1 
ATOM   3132 O OH  . TYR   A 1 389 ? 184.652 137.769 148.474 1.00 74.36  ? 415 TYR   A OH  1 
ATOM   3133 N N   . ARG   A 1 390 ? 181.931 132.463 152.378 1.00 63.49  ? 416 ARG   A N   1 
ATOM   3134 C CA  . ARG   A 1 390 ? 183.202 131.835 152.721 1.00 67.76  ? 416 ARG   A CA  1 
ATOM   3135 C C   . ARG   A 1 390 ? 183.716 131.088 151.499 1.00 75.07  ? 416 ARG   A C   1 
ATOM   3136 O O   . ARG   A 1 390 ? 183.056 130.166 151.009 1.00 77.19  ? 416 ARG   A O   1 
ATOM   3137 C CB  . ARG   A 1 390 ? 183.044 130.887 153.911 1.00 71.09  ? 416 ARG   A CB  1 
ATOM   3138 C CG  . ARG   A 1 390 ? 184.337 130.191 154.333 1.00 73.86  ? 416 ARG   A CG  1 
ATOM   3139 C CD  . ARG   A 1 390 ? 184.159 129.322 155.570 1.00 70.61  ? 416 ARG   A CD  1 
ATOM   3140 N NE  . ARG   A 1 390 ? 184.320 130.072 156.811 1.00 69.22  ? 416 ARG   A NE  1 
ATOM   3141 C CZ  . ARG   A 1 390 ? 183.344 130.648 157.504 1.00 77.89  ? 416 ARG   A CZ  1 
ATOM   3142 N NH1 . ARG   A 1 390 ? 182.080 130.603 157.107 1.00 81.80  ? 416 ARG   A NH1 1 
ATOM   3143 N NH2 . ARG   A 1 390 ? 183.643 131.287 158.631 1.00 78.01  ? 416 ARG   A NH2 1 
ATOM   3144 N N   . ASP   A 1 391 ? 184.892 131.480 151.018 1.00 82.76  ? 417 ASP   A N   1 
ATOM   3145 C CA  . ASP   A 1 391 ? 185.488 130.818 149.866 1.00 82.10  ? 417 ASP   A CA  1 
ATOM   3146 C C   . ASP   A 1 391 ? 185.861 129.383 150.218 1.00 85.17  ? 417 ASP   A C   1 
ATOM   3147 O O   . ASP   A 1 391 ? 186.411 129.110 151.288 1.00 88.96  ? 417 ASP   A O   1 
ATOM   3148 C CB  . ASP   A 1 391 ? 186.722 131.587 149.400 1.00 84.93  ? 417 ASP   A CB  1 
ATOM   3149 C CG  . ASP   A 1 391 ? 187.390 130.947 148.204 1.00 97.41  ? 417 ASP   A CG  1 
ATOM   3150 O OD1 . ASP   A 1 391 ? 186.809 130.996 147.100 1.00 97.22  ? 417 ASP   A OD1 1 
ATOM   3151 O OD2 . ASP   A 1 391 ? 188.497 130.392 148.366 1.00 105.23 ? 417 ASP   A OD2 1 
ATOM   3152 N N   . GLY   A 1 392 ? 185.561 128.463 149.307 1.00 83.43  ? 418 GLY   A N   1 
ATOM   3153 C CA  . GLY   A 1 392 ? 185.713 127.048 149.561 1.00 83.01  ? 418 GLY   A CA  1 
ATOM   3154 C C   . GLY   A 1 392 ? 187.085 126.466 149.318 1.00 93.06  ? 418 GLY   A C   1 
ATOM   3155 O O   . GLY   A 1 392 ? 187.267 125.261 149.518 1.00 97.49  ? 418 GLY   A O   1 
ATOM   3156 N N   . ARG   A 1 393 ? 188.057 127.276 148.899 1.00 97.64  ? 419 ARG   A N   1 
ATOM   3157 C CA  . ARG   A 1 393 ? 189.419 126.825 148.636 1.00 100.28 ? 419 ARG   A CA  1 
ATOM   3158 C C   . ARG   A 1 393 ? 190.417 127.370 149.645 1.00 98.25  ? 419 ARG   A C   1 
ATOM   3159 O O   . ARG   A 1 393 ? 191.252 126.618 150.155 1.00 100.63 ? 419 ARG   A O   1 
ATOM   3160 C CB  . ARG   A 1 393 ? 189.835 127.242 147.216 1.00 107.48 ? 419 ARG   A CB  1 
ATOM   3161 C CG  . ARG   A 1 393 ? 191.179 126.679 146.745 1.00 114.02 ? 419 ARG   A CG  1 
ATOM   3162 C CD  . ARG   A 1 393 ? 191.574 127.231 145.380 1.00 116.80 ? 419 ARG   A CD  1 
ATOM   3163 N NE  . ARG   A 1 393 ? 191.801 128.672 145.416 1.00 120.69 ? 419 ARG   A NE  1 
ATOM   3164 C CZ  . ARG   A 1 393 ? 192.157 129.413 144.374 1.00 124.64 ? 419 ARG   A CZ  1 
ATOM   3165 N NH1 . ARG   A 1 393 ? 192.347 128.884 143.174 1.00 122.27 ? 419 ARG   A NH1 1 
ATOM   3166 N NH2 . ARG   A 1 393 ? 192.325 130.722 144.538 1.00 125.29 ? 419 ARG   A NH2 1 
ATOM   3167 N N   . THR   A 1 394 ? 190.341 128.665 149.952 1.00 95.23  ? 420 THR   A N   1 
ATOM   3168 C CA  . THR   A 1 394 ? 191.308 129.328 150.818 1.00 97.01  ? 420 THR   A CA  1 
ATOM   3169 C C   . THR   A 1 394 ? 190.790 129.557 152.230 1.00 91.92  ? 420 THR   A C   1 
ATOM   3170 O O   . THR   A 1 394 ? 191.595 129.624 153.165 1.00 87.62  ? 420 THR   A O   1 
ATOM   3171 C CB  . THR   A 1 394 ? 191.715 130.677 150.213 1.00 98.67  ? 420 THR   A CB  1 
ATOM   3172 O OG1 . THR   A 1 394 ? 192.122 130.491 148.852 1.00 99.14  ? 420 THR   A OG1 1 
ATOM   3173 C CG2 . THR   A 1 394 ? 192.861 131.305 150.999 1.00 93.95  ? 420 THR   A CG2 1 
ATOM   3174 N N   . GLY   A 1 395 ? 189.478 129.675 152.405 1.00 87.75  ? 421 GLY   A N   1 
ATOM   3175 C CA  . GLY   A 1 395 ? 188.888 129.952 153.697 1.00 84.36  ? 421 GLY   A CA  1 
ATOM   3176 C C   . GLY   A 1 395 ? 188.610 131.410 153.979 1.00 80.47  ? 421 GLY   A C   1 
ATOM   3177 O O   . GLY   A 1 395 ? 188.206 131.736 155.100 1.00 83.42  ? 421 GLY   A O   1 
ATOM   3178 N N   . GLU   A 1 396 ? 188.813 132.295 153.007 1.00 78.96  ? 422 GLU   A N   1 
ATOM   3179 C CA  . GLU   A 1 396 ? 188.560 133.710 153.220 1.00 77.26  ? 422 GLU   A CA  1 
ATOM   3180 C C   . GLU   A 1 396 ? 187.073 133.961 153.432 1.00 75.89  ? 422 GLU   A C   1 
ATOM   3181 O O   . GLU   A 1 396 ? 186.219 133.221 152.938 1.00 82.42  ? 422 GLU   A O   1 
ATOM   3182 C CB  . GLU   A 1 396 ? 189.055 134.527 152.029 1.00 83.92  ? 422 GLU   A CB  1 
ATOM   3183 C CG  . GLU   A 1 396 ? 190.551 134.447 151.798 1.00 90.68  ? 422 GLU   A CG  1 
ATOM   3184 C CD  . GLU   A 1 396 ? 190.993 135.240 150.586 1.00 100.51 ? 422 GLU   A CD  1 
ATOM   3185 O OE1 . GLU   A 1 396 ? 190.123 135.829 149.911 1.00 101.06 ? 422 GLU   A OE1 1 
ATOM   3186 O OE2 . GLU   A 1 396 ? 192.210 135.275 150.307 1.00 101.42 ? 422 GLU   A OE2 1 
ATOM   3187 N N   . LEU   A 1 397 ? 186.774 135.024 154.175 1.00 68.00  ? 423 LEU   A N   1 
ATOM   3188 C CA  . LEU   A 1 397 ? 185.412 135.433 154.488 1.00 64.00  ? 423 LEU   A CA  1 
ATOM   3189 C C   . LEU   A 1 397 ? 185.198 136.845 153.966 1.00 60.74  ? 423 LEU   A C   1 
ATOM   3190 O O   . LEU   A 1 397 ? 185.975 137.750 154.286 1.00 69.34  ? 423 LEU   A O   1 
ATOM   3191 C CB  . LEU   A 1 397 ? 185.160 135.373 155.998 1.00 63.40  ? 423 LEU   A CB  1 
ATOM   3192 C CG  . LEU   A 1 397 ? 183.705 135.430 156.464 1.00 70.99  ? 423 LEU   A CG  1 
ATOM   3193 C CD1 . LEU   A 1 397 ? 182.953 134.163 156.074 1.00 71.28  ? 423 LEU   A CD1 1 
ATOM   3194 C CD2 . LEU   A 1 397 ? 183.636 135.654 157.968 1.00 72.52  ? 423 LEU   A CD2 1 
ATOM   3195 N N   . GLY   A 1 398 ? 184.150 137.025 153.154 1.00 54.99  ? 424 GLY   A N   1 
ATOM   3196 C CA  . GLY   A 1 398 ? 183.858 138.308 152.555 1.00 57.35  ? 424 GLY   A CA  1 
ATOM   3197 C C   . GLY   A 1 398 ? 182.369 138.601 152.612 1.00 57.69  ? 424 GLY   A C   1 
ATOM   3198 O O   . GLY   A 1 398 ? 181.564 137.756 153.010 1.00 69.01  ? 424 GLY   A O   1 
ATOM   3199 N N   . TYR   A 1 399 ? 182.020 139.821 152.211 1.00 46.77  ? 425 TYR   A N   1 
ATOM   3200 C CA  . TYR   A 1 399 ? 180.656 140.323 152.302 1.00 45.21  ? 425 TYR   A CA  1 
ATOM   3201 C C   . TYR   A 1 399 ? 180.217 140.866 150.950 1.00 45.98  ? 425 TYR   A C   1 
ATOM   3202 O O   . TYR   A 1 399 ? 180.946 141.643 150.325 1.00 56.78  ? 425 TYR   A O   1 
ATOM   3203 C CB  . TYR   A 1 399 ? 180.557 141.406 153.379 1.00 48.48  ? 425 TYR   A CB  1 
ATOM   3204 C CG  . TYR   A 1 399 ? 181.166 140.983 154.697 1.00 48.86  ? 425 TYR   A CG  1 
ATOM   3205 C CD1 . TYR   A 1 399 ? 180.414 140.311 155.646 1.00 52.02  ? 425 TYR   A CD1 1 
ATOM   3206 C CD2 . TYR   A 1 399 ? 182.494 141.248 154.986 1.00 54.30  ? 425 TYR   A CD2 1 
ATOM   3207 C CE1 . TYR   A 1 399 ? 180.968 139.919 156.847 1.00 55.34  ? 425 TYR   A CE1 1 
ATOM   3208 C CE2 . TYR   A 1 399 ? 183.055 140.860 156.181 1.00 57.94  ? 425 TYR   A CE2 1 
ATOM   3209 C CZ  . TYR   A 1 399 ? 182.289 140.196 157.108 1.00 59.71  ? 425 TYR   A CZ  1 
ATOM   3210 O OH  . TYR   A 1 399 ? 182.846 139.808 158.303 1.00 66.80  ? 425 TYR   A OH  1 
ATOM   3211 N N   . LEU   A 1 400 ? 179.033 140.454 150.506 1.00 48.89  ? 426 LEU   A N   1 
ATOM   3212 C CA  . LEU   A 1 400 ? 178.442 140.911 149.256 1.00 54.51  ? 426 LEU   A CA  1 
ATOM   3213 C C   . LEU   A 1 400 ? 177.455 142.043 149.510 1.00 59.24  ? 426 LEU   A C   1 
ATOM   3214 O O   . LEU   A 1 400 ? 176.959 142.233 150.623 1.00 59.33  ? 426 LEU   A O   1 
ATOM   3215 C CB  . LEU   A 1 400 ? 177.729 139.766 148.531 1.00 54.62  ? 426 LEU   A CB  1 
ATOM   3216 C CG  . LEU   A 1 400 ? 178.571 138.674 147.868 1.00 60.44  ? 426 LEU   A CG  1 
ATOM   3217 C CD1 . LEU   A 1 400 ? 177.664 137.614 147.280 1.00 60.54  ? 426 LEU   A CD1 1 
ATOM   3218 C CD2 . LEU   A 1 400 ? 179.475 139.244 146.790 1.00 64.53  ? 426 LEU   A CD2 1 
ATOM   3219 N N   . ASN   A 1 401 ? 177.177 142.802 148.453 1.00 60.07  ? 427 ASN   A N   1 
ATOM   3220 C CA  . ASN   A 1 401 ? 176.213 143.883 148.551 1.00 54.26  ? 427 ASN   A CA  1 
ATOM   3221 C C   . ASN   A 1 401 ? 174.818 143.298 148.784 1.00 59.67  ? 427 ASN   A C   1 
ATOM   3222 O O   . ASN   A 1 401 ? 174.544 142.167 148.373 1.00 65.85  ? 427 ASN   A O   1 
ATOM   3223 C CB  . ASN   A 1 401 ? 176.229 144.726 147.277 1.00 51.01  ? 427 ASN   A CB  1 
ATOM   3224 C CG  . ASN   A 1 401 ? 175.962 146.198 147.534 1.00 51.69  ? 427 ASN   A CG  1 
ATOM   3225 O OD1 . ASN   A 1 401 ? 176.364 146.749 148.558 1.00 58.44  ? 427 ASN   A OD1 1 
ATOM   3226 N ND2 . ASN   A 1 401 ? 175.282 146.843 146.598 1.00 50.02  ? 427 ASN   A ND2 1 
ATOM   3227 N N   . PRO   A 1 402 ? 173.922 144.030 149.468 1.00 58.49  ? 428 PRO   A N   1 
ATOM   3228 C CA  . PRO   A 1 402 ? 172.622 143.423 149.814 1.00 56.85  ? 428 PRO   A CA  1 
ATOM   3229 C C   . PRO   A 1 402 ? 171.792 142.962 148.627 1.00 64.33  ? 428 PRO   A C   1 
ATOM   3230 O O   . PRO   A 1 402 ? 171.171 141.894 148.704 1.00 71.27  ? 428 PRO   A O   1 
ATOM   3231 C CB  . PRO   A 1 402 ? 171.910 144.542 150.586 1.00 60.32  ? 428 PRO   A CB  1 
ATOM   3232 C CG  . PRO   A 1 402 ? 172.989 145.395 151.105 1.00 65.12  ? 428 PRO   A CG  1 
ATOM   3233 C CD  . PRO   A 1 402 ? 174.054 145.375 150.062 1.00 64.67  ? 428 PRO   A CD  1 
ATOM   3234 N N   . GLY   A 1 403 ? 171.774 143.719 147.529 1.00 66.13  ? 429 GLY   A N   1 
ATOM   3235 C CA  . GLY   A 1 403 ? 170.839 143.483 146.440 1.00 71.16  ? 429 GLY   A CA  1 
ATOM   3236 C C   . GLY   A 1 403 ? 171.461 143.284 145.073 1.00 69.96  ? 429 GLY   A C   1 
ATOM   3237 O O   . GLY   A 1 403 ? 170.914 143.758 144.073 1.00 75.35  ? 429 GLY   A O   1 
ATOM   3238 N N   . VAL   A 1 404 ? 172.591 142.593 145.004 1.00 64.48  ? 430 VAL   A N   1 
ATOM   3239 C CA  . VAL   A 1 404 ? 173.310 142.444 143.744 1.00 65.64  ? 430 VAL   A CA  1 
ATOM   3240 C C   . VAL   A 1 404 ? 172.633 141.378 142.894 1.00 70.34  ? 430 VAL   A C   1 
ATOM   3241 O O   . VAL   A 1 404 ? 172.115 140.381 143.412 1.00 70.82  ? 430 VAL   A O   1 
ATOM   3242 C CB  . VAL   A 1 404 ? 174.788 142.103 144.008 1.00 68.54  ? 430 VAL   A CB  1 
ATOM   3243 C CG1 . VAL   A 1 404 ? 174.938 140.668 144.496 1.00 67.97  ? 430 VAL   A CG1 1 
ATOM   3244 C CG2 . VAL   A 1 404 ? 175.623 142.340 142.759 1.00 69.90  ? 430 VAL   A CG2 1 
ATOM   3245 N N   . PHE   A 1 405 ? 172.633 141.592 141.576 1.00 71.89  ? 431 PHE   A N   1 
ATOM   3246 C CA  . PHE   A 1 405 ? 172.068 140.646 140.610 1.00 68.92  ? 431 PHE   A CA  1 
ATOM   3247 C C   . PHE   A 1 405 ? 170.581 140.403 140.849 1.00 65.34  ? 431 PHE   A C   1 
ATOM   3248 O O   . PHE   A 1 405 ? 170.093 139.287 140.656 1.00 71.75  ? 431 PHE   A O   1 
ATOM   3249 C CB  . PHE   A 1 405 ? 172.811 139.305 140.630 1.00 69.11  ? 431 PHE   A CB  1 
ATOM   3250 C CG  . PHE   A 1 405 ? 174.296 139.411 140.417 1.00 68.38  ? 431 PHE   A CG  1 
ATOM   3251 C CD1 . PHE   A 1 405 ? 174.841 140.385 139.598 1.00 73.14  ? 431 PHE   A CD1 1 
ATOM   3252 C CD2 . PHE   A 1 405 ? 175.150 138.514 141.033 1.00 64.50  ? 431 PHE   A CD2 1 
ATOM   3253 C CE1 . PHE   A 1 405 ? 176.203 140.466 139.410 1.00 75.21  ? 431 PHE   A CE1 1 
ATOM   3254 C CE2 . PHE   A 1 405 ? 176.511 138.592 140.847 1.00 67.60  ? 431 PHE   A CE2 1 
ATOM   3255 C CZ  . PHE   A 1 405 ? 177.038 139.568 140.035 1.00 73.94  ? 431 PHE   A CZ  1 
ATOM   3256 N N   . THR   A 1 406 ? 169.850 141.432 141.271 1.00 65.40  ? 432 THR   A N   1 
ATOM   3257 C CA  . THR   A 1 406 ? 168.430 141.296 141.561 1.00 70.66  ? 432 THR   A CA  1 
ATOM   3258 C C   . THR   A 1 406 ? 167.706 142.569 141.151 1.00 75.66  ? 432 THR   A C   1 
ATOM   3259 O O   . THR   A 1 406 ? 168.294 143.654 141.124 1.00 79.07  ? 432 THR   A O   1 
ATOM   3260 C CB  . THR   A 1 406 ? 168.199 141.002 143.050 1.00 74.95  ? 432 THR   A CB  1 
ATOM   3261 O OG1 . THR   A 1 406 ? 169.147 140.027 143.499 1.00 78.23  ? 432 THR   A OG1 1 
ATOM   3262 C CG2 . THR   A 1 406 ? 166.795 140.471 143.296 1.00 73.18  ? 432 THR   A CG2 1 
ATOM   3263 N N   . GLN   A 1 407 ? 166.417 142.420 140.826 1.00 78.74  ? 433 GLN   A N   1 
ATOM   3264 C CA  . GLN   A 1 407 ? 165.567 143.526 140.406 1.00 82.54  ? 433 GLN   A CA  1 
ATOM   3265 C C   . GLN   A 1 407 ? 164.397 143.797 141.342 1.00 82.13  ? 433 GLN   A C   1 
ATOM   3266 O O   . GLN   A 1 407 ? 163.696 144.795 141.143 1.00 86.21  ? 433 GLN   A O   1 
ATOM   3267 C CB  . GLN   A 1 407 ? 165.016 143.267 138.995 1.00 78.89  ? 433 GLN   A CB  1 
ATOM   3268 C CG  . GLN   A 1 407 ? 166.075 143.286 137.909 1.00 82.36  ? 433 GLN   A CG  1 
ATOM   3269 C CD  . GLN   A 1 407 ? 165.556 142.779 136.581 1.00 85.78  ? 433 GLN   A CD  1 
ATOM   3270 O OE1 . GLN   A 1 407 ? 164.373 142.469 136.441 1.00 89.13  ? 433 GLN   A OE1 1 
ATOM   3271 N NE2 . GLN   A 1 407 ? 166.441 142.687 135.597 1.00 82.49  ? 433 GLN   A NE2 1 
ATOM   3272 N N   . SER   A 1 408 ? 164.161 142.946 142.338 1.00 71.86  ? 434 SER   A N   1 
ATOM   3273 C CA  . SER   A 1 408 ? 163.099 143.120 143.316 1.00 73.67  ? 434 SER   A CA  1 
ATOM   3274 C C   . SER   A 1 408 ? 163.681 142.991 144.717 1.00 76.70  ? 434 SER   A C   1 
ATOM   3275 O O   . SER   A 1 408 ? 164.874 142.736 144.899 1.00 75.87  ? 434 SER   A O   1 
ATOM   3276 C CB  . SER   A 1 408 ? 161.980 142.092 143.116 1.00 78.29  ? 434 SER   A CB  1 
ATOM   3277 O OG  . SER   A 1 408 ? 161.007 142.198 144.141 1.00 87.29  ? 434 SER   A OG  1 
ATOM   3278 N N   . ARG   A 1 409 ? 162.813 143.185 145.714 1.00 78.31  ? 435 ARG   A N   1 
ATOM   3279 C CA  . ARG   A 1 409 ? 163.189 143.088 147.120 1.00 74.01  ? 435 ARG   A CA  1 
ATOM   3280 C C   . ARG   A 1 409 ? 162.274 142.142 147.893 1.00 75.61  ? 435 ARG   A C   1 
ATOM   3281 O O   . ARG   A 1 409 ? 162.194 142.239 149.121 1.00 81.47  ? 435 ARG   A O   1 
ATOM   3282 C CB  . ARG   A 1 409 ? 163.191 144.475 147.769 1.00 80.87  ? 435 ARG   A CB  1 
ATOM   3283 C CG  . ARG   A 1 409 ? 161.866 145.220 147.678 1.00 89.47  ? 435 ARG   A CG  1 
ATOM   3284 C CD  . ARG   A 1 409 ? 161.975 146.624 148.254 1.00 101.71 ? 435 ARG   A CD  1 
ATOM   3285 N NE  . ARG   A 1 409 ? 162.894 147.463 147.492 1.00 105.24 ? 435 ARG   A NE  1 
ATOM   3286 C CZ  . ARG   A 1 409 ? 163.168 148.733 147.765 1.00 109.88 ? 435 ARG   A CZ  1 
ATOM   3287 N NH1 . ARG   A 1 409 ? 162.607 149.363 148.786 1.00 111.91 ? 435 ARG   A NH1 1 
ATOM   3288 N NH2 . ARG   A 1 409 ? 164.028 149.390 146.992 1.00 105.62 ? 435 ARG   A NH2 1 
ATOM   3289 N N   . ARG   A 1 410 ? 161.590 141.227 147.207 1.00 68.52  ? 436 ARG   A N   1 
ATOM   3290 C CA  . ARG   A 1 410 ? 160.720 140.259 147.861 1.00 67.37  ? 436 ARG   A CA  1 
ATOM   3291 C C   . ARG   A 1 410 ? 161.442 138.982 148.269 1.00 67.86  ? 436 ARG   A C   1 
ATOM   3292 O O   . ARG   A 1 410 ? 160.817 138.105 148.874 1.00 72.16  ? 436 ARG   A O   1 
ATOM   3293 C CB  . ARG   A 1 410 ? 159.543 139.904 146.947 1.00 74.71  ? 436 ARG   A CB  1 
ATOM   3294 C CG  . ARG   A 1 410 ? 158.443 140.950 146.911 1.00 80.35  ? 436 ARG   A CG  1 
ATOM   3295 C CD  . ARG   A 1 410 ? 157.216 140.423 146.188 1.00 83.31  ? 436 ARG   A CD  1 
ATOM   3296 N NE  . ARG   A 1 410 ? 156.193 141.446 146.008 1.00 85.42  ? 436 ARG   A NE  1 
ATOM   3297 C CZ  . ARG   A 1 410 ? 155.028 141.253 145.402 1.00 88.12  ? 436 ARG   A CZ  1 
ATOM   3298 N NH1 . ARG   A 1 410 ? 154.688 140.073 144.904 1.00 85.37  ? 436 ARG   A NH1 1 
ATOM   3299 N NH2 . ARG   A 1 410 ? 154.180 142.271 145.291 1.00 91.11  ? 436 ARG   A NH2 1 
ATOM   3300 N N   . TRP   A 1 411 ? 162.732 138.852 147.966 1.00 62.93  ? 437 TRP   A N   1 
ATOM   3301 C CA  . TRP   A 1 411 ? 163.500 137.701 148.426 1.00 66.62  ? 437 TRP   A CA  1 
ATOM   3302 C C   . TRP   A 1 411 ? 163.860 137.777 149.905 1.00 66.61  ? 437 TRP   A C   1 
ATOM   3303 O O   . TRP   A 1 411 ? 164.394 136.801 150.443 1.00 66.71  ? 437 TRP   A O   1 
ATOM   3304 C CB  . TRP   A 1 411 ? 164.782 137.540 147.598 1.00 63.19  ? 437 TRP   A CB  1 
ATOM   3305 C CG  . TRP   A 1 411 ? 165.699 138.722 147.633 1.00 61.68  ? 437 TRP   A CG  1 
ATOM   3306 C CD1 . TRP   A 1 411 ? 165.724 139.760 146.752 1.00 68.73  ? 437 TRP   A CD1 1 
ATOM   3307 C CD2 . TRP   A 1 411 ? 166.723 138.989 148.595 1.00 58.75  ? 437 TRP   A CD2 1 
ATOM   3308 N NE1 . TRP   A 1 411 ? 166.696 140.659 147.105 1.00 70.75  ? 437 TRP   A NE1 1 
ATOM   3309 C CE2 . TRP   A 1 411 ? 167.324 140.208 148.235 1.00 63.37  ? 437 TRP   A CE2 1 
ATOM   3310 C CE3 . TRP   A 1 411 ? 167.187 138.318 149.727 1.00 62.86  ? 437 TRP   A CE3 1 
ATOM   3311 C CZ2 . TRP   A 1 411 ? 168.364 140.769 148.964 1.00 65.33  ? 437 TRP   A CZ2 1 
ATOM   3312 C CZ3 . TRP   A 1 411 ? 168.220 138.876 150.449 1.00 61.02  ? 437 TRP   A CZ3 1 
ATOM   3313 C CH2 . TRP   A 1 411 ? 168.798 140.089 150.066 1.00 61.89  ? 437 TRP   A CH2 1 
ATOM   3314 N N   . LYS   A 1 412 ? 163.583 138.894 150.572 1.00 64.84  ? 438 LYS   A N   1 
ATOM   3315 C CA  . LYS   A 1 412 ? 163.904 139.069 151.980 1.00 61.81  ? 438 LYS   A CA  1 
ATOM   3316 C C   . LYS   A 1 412 ? 162.822 138.533 152.909 1.00 66.21  ? 438 LYS   A C   1 
ATOM   3317 O O   . LYS   A 1 412 ? 162.990 138.612 154.130 1.00 65.33  ? 438 LYS   A O   1 
ATOM   3318 C CB  . LYS   A 1 412 ? 164.132 140.554 152.285 1.00 61.82  ? 438 LYS   A CB  1 
ATOM   3319 C CG  . LYS   A 1 412 ? 165.151 141.247 151.393 1.00 62.29  ? 438 LYS   A CG  1 
ATOM   3320 C CD  . LYS   A 1 412 ? 165.235 142.727 151.715 1.00 64.89  ? 438 LYS   A CD  1 
ATOM   3321 C CE  . LYS   A 1 412 ? 166.217 143.441 150.809 1.00 68.76  ? 438 LYS   A CE  1 
ATOM   3322 N NZ  . LYS   A 1 412 ? 166.289 144.897 151.106 1.00 71.95  ? 438 LYS   A NZ  1 
ATOM   3323 N N   . ASP   A 1 413 ? 161.724 137.994 152.365 1.00 71.00  ? 439 ASP   A N   1 
ATOM   3324 C CA  . ASP   A 1 413 ? 160.577 137.572 153.157 1.00 68.61  ? 439 ASP   A CA  1 
ATOM   3325 C C   . ASP   A 1 413 ? 160.113 136.151 152.867 1.00 67.86  ? 439 ASP   A C   1 
ATOM   3326 O O   . ASP   A 1 413 ? 159.178 135.686 153.529 1.00 69.12  ? 439 ASP   A O   1 
ATOM   3327 C CB  . ASP   A 1 413 ? 159.398 138.528 152.924 1.00 70.49  ? 439 ASP   A CB  1 
ATOM   3328 C CG  . ASP   A 1 413 ? 159.789 139.981 153.077 1.00 74.80  ? 439 ASP   A CG  1 
ATOM   3329 O OD1 . ASP   A 1 413 ? 160.591 140.291 153.982 1.00 75.56  ? 439 ASP   A OD1 1 
ATOM   3330 O OD2 . ASP   A 1 413 ? 159.298 140.813 152.285 1.00 74.94  ? 439 ASP   A OD2 1 
ATOM   3331 N N   . HIS   A 1 414 ? 160.726 135.450 151.910 1.00 63.64  ? 440 HIS   A N   1 
ATOM   3332 C CA  . HIS   A 1 414 ? 160.313 134.108 151.523 1.00 61.08  ? 440 HIS   A CA  1 
ATOM   3333 C C   . HIS   A 1 414 ? 161.524 133.192 151.445 1.00 62.73  ? 440 HIS   A C   1 
ATOM   3334 O O   . HIS   A 1 414 ? 162.572 133.575 150.918 1.00 72.66  ? 440 HIS   A O   1 
ATOM   3335 C CB  . HIS   A 1 414 ? 159.580 134.128 150.180 1.00 62.32  ? 440 HIS   A CB  1 
ATOM   3336 C CG  . HIS   A 1 414 ? 158.266 134.841 150.225 1.00 65.51  ? 440 HIS   A CG  1 
ATOM   3337 N ND1 . HIS   A 1 414 ? 158.166 136.209 150.355 1.00 65.17  ? 440 HIS   A ND1 1 
ATOM   3338 C CD2 . HIS   A 1 414 ? 156.997 134.375 150.168 1.00 65.64  ? 440 HIS   A CD2 1 
ATOM   3339 C CE1 . HIS   A 1 414 ? 156.891 136.555 150.370 1.00 66.22  ? 440 HIS   A CE1 1 
ATOM   3340 N NE2 . HIS   A 1 414 ? 156.161 135.461 150.258 1.00 64.57  ? 440 HIS   A NE2 1 
ATOM   3341 N N   . ALA   A 1 415 ? 161.372 131.976 151.978 1.00 53.91  ? 441 ALA   A N   1 
ATOM   3342 C CA  . ALA   A 1 415 ? 162.487 131.035 152.013 1.00 57.90  ? 441 ALA   A CA  1 
ATOM   3343 C C   . ALA   A 1 415 ? 162.839 130.521 150.622 1.00 63.64  ? 441 ALA   A C   1 
ATOM   3344 O O   . ALA   A 1 415 ? 164.022 130.379 150.291 1.00 65.43  ? 441 ALA   A O   1 
ATOM   3345 C CB  . ALA   A 1 415 ? 162.154 129.868 152.940 1.00 63.21  ? 441 ALA   A CB  1 
ATOM   3346 N N   . ASP   A 1 416 ? 161.831 130.219 149.802 1.00 64.69  ? 442 ASP   A N   1 
ATOM   3347 C CA  . ASP   A 1 416 ? 162.098 129.649 148.483 1.00 65.24  ? 442 ASP   A CA  1 
ATOM   3348 C C   . ASP   A 1 416 ? 162.842 130.636 147.591 1.00 65.04  ? 442 ASP   A C   1 
ATOM   3349 O O   . ASP   A 1 416 ? 163.778 130.256 146.872 1.00 67.83  ? 442 ASP   A O   1 
ATOM   3350 C CB  . ASP   A 1 416 ? 160.790 129.201 147.828 1.00 67.27  ? 442 ASP   A CB  1 
ATOM   3351 C CG  . ASP   A 1 416 ? 159.780 130.322 147.693 1.00 76.96  ? 442 ASP   A CG  1 
ATOM   3352 O OD1 . ASP   A 1 416 ? 159.546 131.036 148.689 1.00 74.34  ? 442 ASP   A OD1 1 
ATOM   3353 O OD2 . ASP   A 1 416 ? 159.217 130.487 146.591 1.00 88.01  ? 442 ASP   A OD2 1 
ATOM   3354 N N   . MET   A 1 417 ? 162.440 131.907 147.618 1.00 60.35  ? 443 MET   A N   1 
ATOM   3355 C CA  . MET   A 1 417 ? 163.155 132.916 146.849 1.00 59.83  ? 443 MET   A CA  1 
ATOM   3356 C C   . MET   A 1 417 ? 164.585 133.069 147.348 1.00 58.84  ? 443 MET   A C   1 
ATOM   3357 O O   . MET   A 1 417 ? 165.507 133.284 146.555 1.00 64.68  ? 443 MET   A O   1 
ATOM   3358 C CB  . MET   A 1 417 ? 162.416 134.250 146.913 1.00 63.37  ? 443 MET   A CB  1 
ATOM   3359 C CG  . MET   A 1 417 ? 161.135 134.275 146.096 1.00 65.36  ? 443 MET   A CG  1 
ATOM   3360 S SD  . MET   A 1 417 ? 160.223 135.821 146.234 1.00 69.06  ? 443 MET   A SD  1 
ATOM   3361 C CE  . MET   A 1 417 ? 161.380 136.972 145.498 1.00 72.10  ? 443 MET   A CE  1 
ATOM   3362 N N   . LEU   A 1 418 ? 164.789 132.963 148.661 1.00 55.32  ? 444 LEU   A N   1 
ATOM   3363 C CA  . LEU   A 1 418 ? 166.143 133.019 149.200 1.00 55.21  ? 444 LEU   A CA  1 
ATOM   3364 C C   . LEU   A 1 418 ? 166.981 131.850 148.699 1.00 57.17  ? 444 LEU   A C   1 
ATOM   3365 O O   . LEU   A 1 418 ? 168.163 132.017 148.381 1.00 63.75  ? 444 LEU   A O   1 
ATOM   3366 C CB  . LEU   A 1 418 ? 166.100 133.029 150.725 1.00 55.67  ? 444 LEU   A CB  1 
ATOM   3367 C CG  . LEU   A 1 418 ? 167.376 133.525 151.407 1.00 58.85  ? 444 LEU   A CG  1 
ATOM   3368 C CD1 . LEU   A 1 418 ? 167.554 135.032 151.243 1.00 58.81  ? 444 LEU   A CD1 1 
ATOM   3369 C CD2 . LEU   A 1 418 ? 167.388 133.137 152.876 1.00 60.21  ? 444 LEU   A CD2 1 
ATOM   3370 N N   . LYS   A 1 419 ? 166.391 130.655 148.635 1.00 53.96  ? 445 LYS   A N   1 
ATOM   3371 C CA  . LYS   A 1 419 ? 167.115 129.496 148.119 1.00 53.80  ? 445 LYS   A CA  1 
ATOM   3372 C C   . LYS   A 1 419 ? 167.491 129.689 146.655 1.00 58.40  ? 445 LYS   A C   1 
ATOM   3373 O O   . LYS   A 1 419 ? 168.617 129.375 146.244 1.00 63.98  ? 445 LYS   A O   1 
ATOM   3374 C CB  . LYS   A 1 419 ? 166.262 128.239 148.296 1.00 57.32  ? 445 LYS   A CB  1 
ATOM   3375 C CG  . LYS   A 1 419 ? 166.970 126.921 148.016 1.00 55.28  ? 445 LYS   A CG  1 
ATOM   3376 C CD  . LYS   A 1 419 ? 168.019 126.610 149.060 1.00 57.24  ? 445 LYS   A CD  1 
ATOM   3377 C CE  . LYS   A 1 419 ? 168.493 125.174 148.954 1.00 61.84  ? 445 LYS   A CE  1 
ATOM   3378 N NZ  . LYS   A 1 419 ? 169.092 124.870 147.629 1.00 65.31  ? 445 LYS   A NZ  1 
ATOM   3379 N N   . GLN   A 1 420 ? 166.558 130.204 145.851 1.00 61.08  ? 446 GLN   A N   1 
ATOM   3380 C CA  . GLN   A 1 420 ? 166.862 130.462 144.445 1.00 59.40  ? 446 GLN   A CA  1 
ATOM   3381 C C   . GLN   A 1 420 ? 167.951 131.521 144.303 1.00 56.87  ? 446 GLN   A C   1 
ATOM   3382 O O   . GLN   A 1 420 ? 168.836 131.402 143.446 1.00 61.97  ? 446 GLN   A O   1 
ATOM   3383 C CB  . GLN   A 1 420 ? 165.593 130.883 143.704 1.00 59.25  ? 446 GLN   A CB  1 
ATOM   3384 C CG  . GLN   A 1 420 ? 164.548 129.782 143.626 1.00 59.15  ? 446 GLN   A CG  1 
ATOM   3385 C CD  . GLN   A 1 420 ? 163.299 130.206 142.888 1.00 63.36  ? 446 GLN   A CD  1 
ATOM   3386 O OE1 . GLN   A 1 420 ? 162.195 130.144 143.425 1.00 63.60  ? 446 GLN   A OE1 1 
ATOM   3387 N NE2 . GLN   A 1 420 ? 163.465 130.634 141.644 1.00 67.26  ? 446 GLN   A NE2 1 
ATOM   3388 N N   . TYR   A 1 421 ? 167.907 132.559 145.140 1.00 54.68  ? 447 TYR   A N   1 
ATOM   3389 C CA  . TYR   A 1 421 ? 168.947 133.581 145.117 1.00 54.82  ? 447 TYR   A CA  1 
ATOM   3390 C C   . TYR   A 1 421 ? 170.301 132.996 145.493 1.00 54.71  ? 447 TYR   A C   1 
ATOM   3391 O O   . TYR   A 1 421 ? 171.327 133.345 144.896 1.00 63.15  ? 447 TYR   A O   1 
ATOM   3392 C CB  . TYR   A 1 421 ? 168.574 134.721 146.063 1.00 57.92  ? 447 TYR   A CB  1 
ATOM   3393 C CG  . TYR   A 1 421 ? 169.556 135.866 146.070 1.00 55.75  ? 447 TYR   A CG  1 
ATOM   3394 C CD1 . TYR   A 1 421 ? 169.715 136.674 144.959 1.00 56.82  ? 447 TYR   A CD1 1 
ATOM   3395 C CD2 . TYR   A 1 421 ? 170.311 136.149 147.194 1.00 57.17  ? 447 TYR   A CD2 1 
ATOM   3396 C CE1 . TYR   A 1 421 ? 170.606 137.723 144.962 1.00 58.84  ? 447 TYR   A CE1 1 
ATOM   3397 C CE2 . TYR   A 1 421 ? 171.200 137.195 147.205 1.00 56.92  ? 447 TYR   A CE2 1 
ATOM   3398 C CZ  . TYR   A 1 421 ? 171.345 137.979 146.086 1.00 55.86  ? 447 TYR   A CZ  1 
ATOM   3399 O OH  . TYR   A 1 421 ? 172.234 139.026 146.093 1.00 65.47  ? 447 TYR   A OH  1 
ATOM   3400 N N   . ALA   A 1 422 ? 170.326 132.112 146.491 1.00 52.22  ? 448 ALA   A N   1 
ATOM   3401 C CA  . ALA   A 1 422 ? 171.575 131.473 146.884 1.00 52.95  ? 448 ALA   A CA  1 
ATOM   3402 C C   . ALA   A 1 422 ? 172.137 130.625 145.753 1.00 54.44  ? 448 ALA   A C   1 
ATOM   3403 O O   . ALA   A 1 422 ? 173.346 130.643 145.499 1.00 65.33  ? 448 ALA   A O   1 
ATOM   3404 C CB  . ALA   A 1 422 ? 171.360 130.624 148.135 1.00 56.29  ? 448 ALA   A CB  1 
ATOM   3405 N N   . THR   A 1 423 ? 171.278 129.874 145.062 1.00 49.24  ? 449 THR   A N   1 
ATOM   3406 C CA  . THR   A 1 423 ? 171.753 129.071 143.937 1.00 52.43  ? 449 THR   A CA  1 
ATOM   3407 C C   . THR   A 1 423 ? 172.280 129.957 142.811 1.00 59.65  ? 449 THR   A C   1 
ATOM   3408 O O   . THR   A 1 423 ? 173.306 129.646 142.187 1.00 65.48  ? 449 THR   A O   1 
ATOM   3409 C CB  . THR   A 1 423 ? 170.632 128.168 143.425 1.00 57.14  ? 449 THR   A CB  1 
ATOM   3410 O OG1 . THR   A 1 423 ? 170.141 127.354 144.496 1.00 59.26  ? 449 THR   A OG1 1 
ATOM   3411 C CG2 . THR   A 1 423 ? 171.136 127.269 142.304 1.00 58.04  ? 449 THR   A CG2 1 
ATOM   3412 N N   . CYS   A 1 424 ? 171.588 131.067 142.538 1.00 59.39  ? 450 CYS   A N   1 
ATOM   3413 C CA  . CYS   A 1 424 ? 172.044 132.007 141.518 1.00 60.02  ? 450 CYS   A CA  1 
ATOM   3414 C C   . CYS   A 1 424 ? 173.421 132.561 141.863 1.00 61.94  ? 450 CYS   A C   1 
ATOM   3415 O O   . CYS   A 1 424 ? 174.323 132.605 141.015 1.00 68.92  ? 450 CYS   A O   1 
ATOM   3416 C CB  . CYS   A 1 424 ? 171.030 133.142 141.382 1.00 65.99  ? 450 CYS   A CB  1 
ATOM   3417 S SG  . CYS   A 1 424 ? 171.419 134.377 140.128 1.00 88.11  ? 450 CYS   A SG  1 
ATOM   3418 N N   . LEU   A 1 425 ? 173.601 132.983 143.116 1.00 57.29  ? 451 LEU   A N   1 
ATOM   3419 C CA  . LEU   A 1 425 ? 174.897 133.496 143.544 1.00 56.19  ? 451 LEU   A CA  1 
ATOM   3420 C C   . LEU   A 1 425 ? 175.967 132.420 143.452 1.00 57.80  ? 451 LEU   A C   1 
ATOM   3421 O O   . LEU   A 1 425 ? 177.100 132.698 143.048 1.00 68.04  ? 451 LEU   A O   1 
ATOM   3422 C CB  . LEU   A 1 425 ? 174.815 134.035 144.973 1.00 56.07  ? 451 LEU   A CB  1 
ATOM   3423 C CG  . LEU   A 1 425 ? 174.289 135.454 145.194 1.00 59.31  ? 451 LEU   A CG  1 
ATOM   3424 C CD1 . LEU   A 1 425 ? 174.179 135.719 146.684 1.00 64.17  ? 451 LEU   A CD1 1 
ATOM   3425 C CD2 . LEU   A 1 425 ? 175.183 136.494 144.529 1.00 62.20  ? 451 LEU   A CD2 1 
ATOM   3426 N N   . SER   A 1 426 ? 175.631 131.187 143.830 1.00 56.52  ? 452 SER   A N   1 
ATOM   3427 C CA  . SER   A 1 426 ? 176.615 130.113 143.784 1.00 59.81  ? 452 SER   A CA  1 
ATOM   3428 C C   . SER   A 1 426 ? 177.084 129.861 142.360 1.00 66.15  ? 452 SER   A C   1 
ATOM   3429 O O   . SER   A 1 426 ? 178.279 129.648 142.123 1.00 67.62  ? 452 SER   A O   1 
ATOM   3430 C CB  . SER   A 1 426 ? 176.029 128.838 144.386 1.00 62.57  ? 452 SER   A CB  1 
ATOM   3431 O OG  . SER   A 1 426 ? 176.960 127.773 144.318 1.00 65.41  ? 452 SER   A OG  1 
ATOM   3432 N N   . ARG   A 1 427 ? 176.164 129.885 141.392 1.00 70.25  ? 453 ARG   A N   1 
ATOM   3433 C CA  . ARG   A 1 427 ? 176.578 129.653 140.013 1.00 70.08  ? 453 ARG   A CA  1 
ATOM   3434 C C   . ARG   A 1 427 ? 177.283 130.854 139.388 1.00 69.66  ? 453 ARG   A C   1 
ATOM   3435 O O   . ARG   A 1 427 ? 178.110 130.657 138.492 1.00 76.32  ? 453 ARG   A O   1 
ATOM   3436 C CB  . ARG   A 1 427 ? 175.383 129.242 139.142 1.00 69.44  ? 453 ARG   A CB  1 
ATOM   3437 C CG  . ARG   A 1 427 ? 174.320 130.306 138.915 1.00 78.00  ? 453 ARG   A CG  1 
ATOM   3438 C CD  . ARG   A 1 427 ? 173.267 129.826 137.930 1.00 84.59  ? 453 ARG   A CD  1 
ATOM   3439 N NE  . ARG   A 1 427 ? 172.482 130.930 137.388 1.00 90.86  ? 453 ARG   A NE  1 
ATOM   3440 C CZ  . ARG   A 1 427 ? 171.580 130.817 136.421 1.00 97.68  ? 453 ARG   A CZ  1 
ATOM   3441 N NH1 . ARG   A 1 427 ? 171.310 129.651 135.852 1.00 95.82  ? 453 ARG   A NH1 1 
ATOM   3442 N NH2 . ARG   A 1 427 ? 170.932 131.903 136.010 1.00 97.26  ? 453 ARG   A NH2 1 
ATOM   3443 N N   . LEU   A 1 428 ? 176.991 132.083 139.834 1.00 63.26  ? 454 LEU   A N   1 
ATOM   3444 C CA  . LEU   A 1 428 ? 177.552 133.271 139.190 1.00 58.49  ? 454 LEU   A CA  1 
ATOM   3445 C C   . LEU   A 1 428 ? 178.826 133.796 139.843 1.00 63.07  ? 454 LEU   A C   1 
ATOM   3446 O O   . LEU   A 1 428 ? 179.592 134.497 139.173 1.00 70.07  ? 454 LEU   A O   1 
ATOM   3447 C CB  . LEU   A 1 428 ? 176.519 134.407 139.166 1.00 60.08  ? 454 LEU   A CB  1 
ATOM   3448 C CG  . LEU   A 1 428 ? 175.256 134.222 138.318 1.00 73.84  ? 454 LEU   A CG  1 
ATOM   3449 C CD1 . LEU   A 1 428 ? 174.363 135.444 138.443 1.00 77.91  ? 454 LEU   A CD1 1 
ATOM   3450 C CD2 . LEU   A 1 428 ? 175.581 133.955 136.855 1.00 77.84  ? 454 LEU   A CD2 1 
ATOM   3451 N N   . LEU   A 1 429 ? 179.069 133.497 141.118 1.00 65.80  ? 455 LEU   A N   1 
ATOM   3452 C CA  . LEU   A 1 429 ? 180.253 134.027 141.793 1.00 65.73  ? 455 LEU   A CA  1 
ATOM   3453 C C   . LEU   A 1 429 ? 181.582 133.626 141.162 1.00 71.41  ? 455 LEU   A C   1 
ATOM   3454 O O   . LEU   A 1 429 ? 182.506 134.458 141.179 1.00 77.82  ? 455 LEU   A O   1 
ATOM   3455 C CB  . LEU   A 1 429 ? 180.232 133.625 143.273 1.00 61.33  ? 455 LEU   A CB  1 
ATOM   3456 C CG  . LEU   A 1 429 ? 179.431 134.530 144.215 1.00 62.10  ? 455 LEU   A CG  1 
ATOM   3457 C CD1 . LEU   A 1 429 ? 179.338 133.889 145.587 1.00 66.72  ? 455 LEU   A CD1 1 
ATOM   3458 C CD2 . LEU   A 1 429 ? 180.043 135.921 144.314 1.00 60.37  ? 455 LEU   A CD2 1 
ATOM   3459 N N   . PRO   A 1 430 ? 181.775 132.407 140.639 1.00 70.90  ? 456 PRO   A N   1 
ATOM   3460 C CA  . PRO   A 1 430 ? 183.077 132.066 140.034 1.00 71.22  ? 456 PRO   A CA  1 
ATOM   3461 C C   . PRO   A 1 430 ? 183.551 133.002 138.933 1.00 66.97  ? 456 PRO   A C   1 
ATOM   3462 O O   . PRO   A 1 430 ? 184.742 132.976 138.601 1.00 70.76  ? 456 PRO   A O   1 
ATOM   3463 C CB  . PRO   A 1 430 ? 182.845 130.648 139.502 1.00 72.07  ? 456 PRO   A CB  1 
ATOM   3464 C CG  . PRO   A 1 430 ? 181.882 130.068 140.461 1.00 71.86  ? 456 PRO   A CG  1 
ATOM   3465 C CD  . PRO   A 1 430 ? 180.967 131.193 140.870 1.00 69.93  ? 456 PRO   A CD  1 
ATOM   3466 N N   . LYS   A 1 431 ? 182.681 133.833 138.362 1.00 65.96  ? 457 LYS   A N   1 
ATOM   3467 C CA  . LYS   A 1 431 ? 183.135 134.843 137.416 1.00 73.76  ? 457 LYS   A CA  1 
ATOM   3468 C C   . LYS   A 1 431 ? 183.972 135.936 138.073 1.00 75.77  ? 457 LYS   A C   1 
ATOM   3469 O O   . LYS   A 1 431 ? 184.602 136.715 137.350 1.00 81.80  ? 457 LYS   A O   1 
ATOM   3470 C CB  . LYS   A 1 431 ? 181.928 135.464 136.710 1.00 83.15  ? 457 LYS   A CB  1 
ATOM   3471 C CG  . LYS   A 1 431 ? 182.278 136.334 135.511 1.00 85.06  ? 457 LYS   A CG  1 
ATOM   3472 C CD  . LYS   A 1 431 ? 181.061 136.618 134.634 1.00 84.51  ? 457 LYS   A CD  1 
ATOM   3473 C CE  . LYS   A 1 431 ? 180.028 137.480 135.345 1.00 85.62  ? 457 LYS   A CE  1 
ATOM   3474 N NZ  . LYS   A 1 431 ? 178.881 137.816 134.458 1.00 83.42  ? 457 LYS   A NZ  1 
ATOM   3475 N N   . TYR   A 1 432 ? 184.006 136.008 139.407 1.00 80.74  ? 458 TYR   A N   1 
ATOM   3476 C CA  . TYR   A 1 432 ? 184.774 137.002 140.150 1.00 86.98  ? 458 TYR   A CA  1 
ATOM   3477 C C   . TYR   A 1 432 ? 185.787 136.339 141.080 1.00 87.99  ? 458 TYR   A C   1 
ATOM   3478 O O   . TYR   A 1 432 ? 185.994 136.775 142.213 1.00 83.79  ? 458 TYR   A O   1 
ATOM   3479 C CB  . TYR   A 1 432 ? 183.843 137.918 140.940 1.00 75.63  ? 458 TYR   A CB  1 
ATOM   3480 C CG  . TYR   A 1 432 ? 182.809 138.615 140.089 1.00 68.62  ? 458 TYR   A CG  1 
ATOM   3481 C CD1 . TYR   A 1 432 ? 183.078 139.840 139.500 1.00 78.99  ? 458 TYR   A CD1 1 
ATOM   3482 C CD2 . TYR   A 1 432 ? 181.563 138.049 139.877 1.00 67.91  ? 458 TYR   A CD2 1 
ATOM   3483 C CE1 . TYR   A 1 432 ? 182.133 140.481 138.723 1.00 82.00  ? 458 TYR   A CE1 1 
ATOM   3484 C CE2 . TYR   A 1 432 ? 180.614 138.682 139.102 1.00 72.47  ? 458 TYR   A CE2 1 
ATOM   3485 C CZ  . TYR   A 1 432 ? 180.903 139.896 138.527 1.00 78.62  ? 458 TYR   A CZ  1 
ATOM   3486 O OH  . TYR   A 1 432 ? 179.958 140.528 137.754 1.00 78.71  ? 458 TYR   A OH  1 
ATOM   3487 N N   . ASN   A 1 433 ? 186.436 135.274 140.600 1.00 87.55  ? 459 ASN   A N   1 
ATOM   3488 C CA  . ASN   A 1 433 ? 187.554 134.636 141.301 1.00 81.64  ? 459 ASN   A CA  1 
ATOM   3489 C C   . ASN   A 1 433 ? 187.158 134.135 142.689 1.00 83.82  ? 459 ASN   A C   1 
ATOM   3490 O O   . ASN   A 1 433 ? 187.894 134.315 143.662 1.00 91.13  ? 459 ASN   A O   1 
ATOM   3491 C CB  . ASN   A 1 433 ? 188.747 135.588 141.397 1.00 91.70  ? 459 ASN   A CB  1 
ATOM   3492 C CG  . ASN   A 1 433 ? 189.234 136.052 140.038 1.00 110.83 ? 459 ASN   A CG  1 
ATOM   3493 O OD1 . ASN   A 1 433 ? 189.069 135.355 139.037 1.00 112.54 ? 459 ASN   A OD1 1 
ATOM   3494 N ND2 . ASN   A 1 433 ? 189.840 137.233 139.997 1.00 124.35 ? 459 ASN   A ND2 1 
ATOM   3495 N N   . VAL   A 1 434 ? 185.985 133.510 142.786 1.00 79.79  ? 460 VAL   A N   1 
ATOM   3496 C CA  . VAL   A 1 434 ? 185.505 132.886 144.015 1.00 76.01  ? 460 VAL   A CA  1 
ATOM   3497 C C   . VAL   A 1 434 ? 185.233 131.415 143.733 1.00 79.16  ? 460 VAL   A C   1 
ATOM   3498 O O   . VAL   A 1 434 ? 184.498 131.083 142.798 1.00 79.35  ? 460 VAL   A O   1 
ATOM   3499 C CB  . VAL   A 1 434 ? 184.239 133.582 144.550 1.00 74.27  ? 460 VAL   A CB  1 
ATOM   3500 C CG1 . VAL   A 1 434 ? 183.686 132.826 145.743 1.00 79.19  ? 460 VAL   A CG1 1 
ATOM   3501 C CG2 . VAL   A 1 434 ? 184.541 135.025 144.923 1.00 75.61  ? 460 VAL   A CG2 1 
ATOM   3502 N N   . THR   A 1 435 ? 185.806 130.536 144.549 1.00 87.38  ? 461 THR   A N   1 
ATOM   3503 C CA  . THR   A 1 435 ? 185.581 129.104 144.400 1.00 88.14  ? 461 THR   A CA  1 
ATOM   3504 C C   . THR   A 1 435 ? 184.221 128.764 145.007 1.00 84.51  ? 461 THR   A C   1 
ATOM   3505 O O   . THR   A 1 435 ? 183.419 129.653 145.302 1.00 85.72  ? 461 THR   A O   1 
ATOM   3506 C CB  . THR   A 1 435 ? 186.721 128.313 145.036 1.00 97.61  ? 461 THR   A CB  1 
ATOM   3507 O OG1 . THR   A 1 435 ? 186.698 128.487 146.459 1.00 100.30 ? 461 THR   A OG1 1 
ATOM   3508 C CG2 . THR   A 1 435 ? 188.062 128.785 144.488 1.00 99.00  ? 461 THR   A CG2 1 
ATOM   3509 N N   . GLU   A 1 436 ? 183.934 127.465 145.178 1.00 82.37  ? 462 GLU   A N   1 
ATOM   3510 C CA  . GLU   A 1 436 ? 182.627 127.006 145.640 1.00 79.70  ? 462 GLU   A CA  1 
ATOM   3511 C C   . GLU   A 1 436 ? 182.281 127.648 146.983 1.00 77.42  ? 462 GLU   A C   1 
ATOM   3512 O O   . GLU   A 1 436 ? 182.861 127.261 148.006 1.00 89.85  ? 462 GLU   A O   1 
ATOM   3513 C CB  . GLU   A 1 436 ? 182.615 125.483 145.776 1.00 89.47  ? 462 GLU   A CB  1 
ATOM   3514 C CG  . GLU   A 1 436 ? 182.845 124.741 144.469 1.00 100.48 ? 462 GLU   A CG  1 
ATOM   3515 C CD  . GLU   A 1 436 ? 182.747 123.236 144.627 1.00 107.43 ? 462 GLU   A CD  1 
ATOM   3516 O OE1 . GLU   A 1 436 ? 182.410 122.773 145.736 1.00 106.21 ? 462 GLU   A OE1 1 
ATOM   3517 O OE2 . GLU   A 1 436 ? 183.007 122.515 143.640 1.00 108.90 ? 462 GLU   A OE2 1 
ATOM   3518 N N   . PRO   A 1 437 ? 181.356 128.607 147.043 1.00 68.37  ? 463 PRO   A N   1 
ATOM   3519 C CA  . PRO   A 1 437 ? 181.145 129.353 148.283 1.00 70.98  ? 463 PRO   A CA  1 
ATOM   3520 C C   . PRO   A 1 437 ? 180.059 128.747 149.165 1.00 66.16  ? 463 PRO   A C   1 
ATOM   3521 O O   . PRO   A 1 437 ? 179.268 127.902 148.741 1.00 72.56  ? 463 PRO   A O   1 
ATOM   3522 C CB  . PRO   A 1 437 ? 180.717 130.728 147.769 1.00 75.15  ? 463 PRO   A CB  1 
ATOM   3523 C CG  . PRO   A 1 437 ? 179.918 130.410 146.563 1.00 71.71  ? 463 PRO   A CG  1 
ATOM   3524 C CD  . PRO   A 1 437 ? 180.476 129.131 145.978 1.00 69.78  ? 463 PRO   A CD  1 
ATOM   3525 N N   . GLN   A 1 438 ? 180.046 129.200 150.416 1.00 61.47  ? 464 GLN   A N   1 
ATOM   3526 C CA  . GLN   A 1 438 ? 178.951 128.974 151.348 1.00 64.79  ? 464 GLN   A CA  1 
ATOM   3527 C C   . GLN   A 1 438 ? 178.368 130.331 151.704 1.00 58.56  ? 464 GLN   A C   1 
ATOM   3528 O O   . GLN   A 1 438 ? 179.099 131.211 152.164 1.00 70.82  ? 464 GLN   A O   1 
ATOM   3529 C CB  . GLN   A 1 438 ? 179.431 128.260 152.616 1.00 71.57  ? 464 GLN   A CB  1 
ATOM   3530 C CG  . GLN   A 1 438 ? 180.247 127.000 152.375 1.00 73.88  ? 464 GLN   A CG  1 
ATOM   3531 C CD  . GLN   A 1 438 ? 180.749 126.383 153.665 1.00 72.43  ? 464 GLN   A CD  1 
ATOM   3532 O OE1 . GLN   A 1 438 ? 180.185 126.609 154.734 1.00 71.29  ? 464 GLN   A OE1 1 
ATOM   3533 N NE2 . GLN   A 1 438 ? 181.820 125.605 153.571 1.00 69.54  ? 464 GLN   A NE2 1 
ATOM   3534 N N   . ILE   A 1 439 ? 177.059 130.492 151.525 1.00 53.73  ? 465 ILE   A N   1 
ATOM   3535 C CA  . ILE   A 1 439 ? 176.393 131.788 151.633 1.00 55.72  ? 465 ILE   A CA  1 
ATOM   3536 C C   . ILE   A 1 439 ? 175.532 131.788 152.889 1.00 58.85  ? 465 ILE   A C   1 
ATOM   3537 O O   . ILE   A 1 439 ? 174.739 130.864 153.108 1.00 64.49  ? 465 ILE   A O   1 
ATOM   3538 C CB  . ILE   A 1 439 ? 175.554 132.098 150.380 1.00 62.73  ? 465 ILE   A CB  1 
ATOM   3539 C CG1 . ILE   A 1 439 ? 176.377 131.835 149.112 1.00 66.84  ? 465 ILE   A CG1 1 
ATOM   3540 C CG2 . ILE   A 1 439 ? 175.072 133.559 150.384 1.00 63.96  ? 465 ILE   A CG2 1 
ATOM   3541 C CD1 . ILE   A 1 439 ? 175.718 132.293 147.827 1.00 69.32  ? 465 ILE   A CD1 1 
ATOM   3542 N N   . TYR   A 1 440 ? 175.693 132.827 153.707 1.00 53.26  ? 466 TYR   A N   1 
ATOM   3543 C CA  . TYR   A 1 440 ? 174.938 133.027 154.935 1.00 46.41  ? 466 TYR   A CA  1 
ATOM   3544 C C   . TYR   A 1 440 ? 174.184 134.345 154.838 1.00 47.37  ? 466 TYR   A C   1 
ATOM   3545 O O   . TYR   A 1 440 ? 174.702 135.322 154.289 1.00 58.72  ? 466 TYR   A O   1 
ATOM   3546 C CB  . TYR   A 1 440 ? 175.856 133.061 156.160 1.00 47.03  ? 466 TYR   A CB  1 
ATOM   3547 C CG  . TYR   A 1 440 ? 176.798 131.887 156.288 1.00 50.35  ? 466 TYR   A CG  1 
ATOM   3548 C CD1 . TYR   A 1 440 ? 178.013 131.873 155.624 1.00 57.19  ? 466 TYR   A CD1 1 
ATOM   3549 C CD2 . TYR   A 1 440 ? 176.483 130.804 157.091 1.00 54.59  ? 466 TYR   A CD2 1 
ATOM   3550 C CE1 . TYR   A 1 440 ? 178.879 130.809 155.742 1.00 60.62  ? 466 TYR   A CE1 1 
ATOM   3551 C CE2 . TYR   A 1 440 ? 177.345 129.734 157.217 1.00 58.79  ? 466 TYR   A CE2 1 
ATOM   3552 C CZ  . TYR   A 1 440 ? 178.542 129.743 156.540 1.00 60.56  ? 466 TYR   A CZ  1 
ATOM   3553 O OH  . TYR   A 1 440 ? 179.406 128.681 156.659 1.00 65.73  ? 466 TYR   A OH  1 
ATOM   3554 N N   . PHE   A 1 441 ? 172.966 134.369 155.376 1.00 43.55  ? 467 PHE   A N   1 
ATOM   3555 C CA  . PHE   A 1 441 ? 172.102 135.539 155.335 1.00 47.34  ? 467 PHE   A CA  1 
ATOM   3556 C C   . PHE   A 1 441 ? 171.736 135.975 156.746 1.00 58.02  ? 467 PHE   A C   1 
ATOM   3557 O O   . PHE   A 1 441 ? 171.537 135.146 157.638 1.00 65.38  ? 467 PHE   A O   1 
ATOM   3558 C CB  . PHE   A 1 441 ? 170.823 135.257 154.541 1.00 56.34  ? 467 PHE   A CB  1 
ATOM   3559 C CG  . PHE   A 1 441 ? 171.041 135.146 153.059 1.00 60.52  ? 467 PHE   A CG  1 
ATOM   3560 C CD1 . PHE   A 1 441 ? 171.572 133.994 152.508 1.00 63.61  ? 467 PHE   A CD1 1 
ATOM   3561 C CD2 . PHE   A 1 441 ? 170.709 136.189 152.217 1.00 56.85  ? 467 PHE   A CD2 1 
ATOM   3562 C CE1 . PHE   A 1 441 ? 171.770 133.890 151.149 1.00 59.92  ? 467 PHE   A CE1 1 
ATOM   3563 C CE2 . PHE   A 1 441 ? 170.906 136.086 150.858 1.00 58.99  ? 467 PHE   A CE2 1 
ATOM   3564 C CZ  . PHE   A 1 441 ? 171.438 134.936 150.325 1.00 58.41  ? 467 PHE   A CZ  1 
ATOM   3565 N N   . ASP   A 1 442 ? 171.640 137.289 156.932 1.00 62.14  ? 468 ASP   A N   1 
ATOM   3566 C CA  . ASP   A 1 442 ? 171.228 137.887 158.200 1.00 56.78  ? 468 ASP   A CA  1 
ATOM   3567 C C   . ASP   A 1 442 ? 170.349 139.082 157.866 1.00 53.28  ? 468 ASP   A C   1 
ATOM   3568 O O   . ASP   A 1 442 ? 170.855 140.114 157.413 1.00 61.11  ? 468 ASP   A O   1 
ATOM   3569 C CB  . ASP   A 1 442 ? 172.436 138.308 159.034 1.00 59.25  ? 468 ASP   A CB  1 
ATOM   3570 C CG  . ASP   A 1 442 ? 172.043 138.973 160.336 1.00 69.91  ? 468 ASP   A CG  1 
ATOM   3571 O OD1 . ASP   A 1 442 ? 170.886 138.798 160.771 1.00 72.39  ? 468 ASP   A OD1 1 
ATOM   3572 O OD2 . ASP   A 1 442 ? 172.892 139.674 160.924 1.00 72.19  ? 468 ASP   A OD2 1 
ATOM   3573 N N   . ILE   A 1 443 ? 169.044 138.945 158.087 1.00 47.86  ? 469 ILE   A N   1 
ATOM   3574 C CA  . ILE   A 1 443 ? 168.056 139.932 157.668 1.00 49.81  ? 469 ILE   A CA  1 
ATOM   3575 C C   . ILE   A 1 443 ? 167.224 140.318 158.880 1.00 55.13  ? 469 ILE   A C   1 
ATOM   3576 O O   . ILE   A 1 443 ? 166.831 139.455 159.671 1.00 59.03  ? 469 ILE   A O   1 
ATOM   3577 C CB  . ILE   A 1 443 ? 167.150 139.393 156.540 1.00 50.46  ? 469 ILE   A CB  1 
ATOM   3578 C CG1 . ILE   A 1 443 ? 167.963 139.076 155.280 1.00 55.62  ? 469 ILE   A CG1 1 
ATOM   3579 C CG2 . ILE   A 1 443 ? 166.059 140.401 156.217 1.00 54.56  ? 469 ILE   A CG2 1 
ATOM   3580 C CD1 . ILE   A 1 443 ? 167.264 138.146 154.311 1.00 60.70  ? 469 ILE   A CD1 1 
ATOM   3581 N N   . TRP   A 1 444 ? 166.947 141.614 159.015 1.00 52.89  ? 470 TRP   A N   1 
ATOM   3582 C CA  . TRP   A 1 444 ? 166.182 142.164 160.127 1.00 45.75  ? 470 TRP   A CA  1 
ATOM   3583 C C   . TRP   A 1 444 ? 164.918 142.808 159.581 1.00 49.98  ? 470 TRP   A C   1 
ATOM   3584 O O   . TRP   A 1 444 ? 164.993 143.725 158.758 1.00 55.26  ? 470 TRP   A O   1 
ATOM   3585 C CB  . TRP   A 1 444 ? 167.007 143.195 160.901 1.00 45.70  ? 470 TRP   A CB  1 
ATOM   3586 C CG  . TRP   A 1 444 ? 168.263 142.645 161.491 1.00 47.27  ? 470 TRP   A CG  1 
ATOM   3587 C CD1 . TRP   A 1 444 ? 169.438 142.417 160.845 1.00 51.24  ? 470 TRP   A CD1 1 
ATOM   3588 C CD2 . TRP   A 1 444 ? 168.473 142.263 162.852 1.00 48.18  ? 470 TRP   A CD2 1 
ATOM   3589 N NE1 . TRP   A 1 444 ? 170.367 141.909 161.717 1.00 60.10  ? 470 TRP   A NE1 1 
ATOM   3590 C CE2 . TRP   A 1 444 ? 169.797 141.804 162.957 1.00 51.06  ? 470 TRP   A CE2 1 
ATOM   3591 C CE3 . TRP   A 1 444 ? 167.667 142.258 163.992 1.00 51.60  ? 470 TRP   A CE3 1 
ATOM   3592 C CZ2 . TRP   A 1 444 ? 170.334 141.349 164.153 1.00 55.88  ? 470 TRP   A CZ2 1 
ATOM   3593 C CZ3 . TRP   A 1 444 ? 168.201 141.805 165.176 1.00 53.42  ? 470 TRP   A CZ3 1 
ATOM   3594 C CH2 . TRP   A 1 444 ? 169.522 141.358 165.250 1.00 59.42  ? 470 TRP   A CH2 1 
ATOM   3595 N N   . VAL   A 1 445 ? 163.764 142.351 160.063 1.00 51.88  ? 471 VAL   A N   1 
ATOM   3596 C CA  . VAL   A 1 445 ? 162.472 142.787 159.541 1.00 51.36  ? 471 VAL   A CA  1 
ATOM   3597 C C   . VAL   A 1 445 ? 161.459 142.766 160.676 1.00 54.41  ? 471 VAL   A C   1 
ATOM   3598 O O   . VAL   A 1 445 ? 161.509 141.899 161.552 1.00 58.99  ? 471 VAL   A O   1 
ATOM   3599 C CB  . VAL   A 1 445 ? 162.019 141.898 158.360 1.00 58.36  ? 471 VAL   A CB  1 
ATOM   3600 C CG1 . VAL   A 1 445 ? 162.176 140.419 158.698 1.00 59.37  ? 471 VAL   A CG1 1 
ATOM   3601 C CG2 . VAL   A 1 445 ? 160.583 142.203 157.962 1.00 58.15  ? 471 VAL   A CG2 1 
ATOM   3602 N N   . SER   A 1 446 ? 160.544 143.734 160.657 1.00 56.87  ? 472 SER   A N   1 
ATOM   3603 C CA  . SER   A 1 446 ? 159.439 143.810 161.601 1.00 59.11  ? 472 SER   A CA  1 
ATOM   3604 C C   . SER   A 1 446 ? 158.141 143.997 160.833 1.00 62.21  ? 472 SER   A C   1 
ATOM   3605 O O   . SER   A 1 446 ? 158.075 144.804 159.898 1.00 67.15  ? 472 SER   A O   1 
ATOM   3606 C CB  . SER   A 1 446 ? 159.620 144.964 162.585 1.00 63.75  ? 472 SER   A CB  1 
ATOM   3607 O OG  . SER   A 1 446 ? 159.459 146.211 161.933 1.00 66.95  ? 472 SER   A OG  1 
ATOM   3608 N N   . ILE   A 1 447 ? 157.111 143.260 161.246 1.00 64.89  ? 473 ILE   A N   1 
ATOM   3609 C CA  . ILE   A 1 447 ? 155.793 143.285 160.619 1.00 66.86  ? 473 ILE   A CA  1 
ATOM   3610 C C   . ILE   A 1 447 ? 154.835 143.988 161.569 1.00 67.03  ? 473 ILE   A C   1 
ATOM   3611 O O   . ILE   A 1 447 ? 154.708 143.598 162.735 1.00 73.77  ? 473 ILE   A O   1 
ATOM   3612 C CB  . ILE   A 1 447 ? 155.294 141.870 160.276 1.00 66.12  ? 473 ILE   A CB  1 
ATOM   3613 C CG1 . ILE   A 1 447 ? 156.084 141.318 159.084 1.00 70.75  ? 473 ILE   A CG1 1 
ATOM   3614 C CG2 . ILE   A 1 447 ? 153.772 141.882 160.002 1.00 68.80  ? 473 ILE   A CG2 1 
ATOM   3615 C CD1 . ILE   A 1 447 ? 155.792 139.869 158.733 1.00 70.85  ? 473 ILE   A CD1 1 
ATOM   3616 N N   . ASN   A 1 448 ? 154.153 145.016 161.062 1.00 63.64  ? 474 ASN   A N   1 
ATOM   3617 C CA  . ASN   A 1 448 ? 153.141 145.754 161.819 1.00 61.07  ? 474 ASN   A CA  1 
ATOM   3618 C C   . ASN   A 1 448 ? 153.731 146.363 163.090 1.00 66.69  ? 474 ASN   A C   1 
ATOM   3619 O O   . ASN   A 1 448 ? 153.159 146.271 164.177 1.00 71.57  ? 474 ASN   A O   1 
ATOM   3620 C CB  . ASN   A 1 448 ? 151.938 144.864 162.142 1.00 69.98  ? 474 ASN   A CB  1 
ATOM   3621 C CG  . ASN   A 1 448 ? 151.153 144.478 160.905 1.00 74.19  ? 474 ASN   A CG  1 
ATOM   3622 O OD1 . ASN   A 1 448 ? 151.046 145.255 159.959 1.00 72.38  ? 474 ASN   A OD1 1 
ATOM   3623 N ND2 . ASN   A 1 448 ? 150.595 143.274 160.909 1.00 79.77  ? 474 ASN   A ND2 1 
ATOM   3624 N N   . ASP   A 1 449 ? 154.892 146.998 162.936 1.00 71.36  ? 475 ASP   A N   1 
ATOM   3625 C CA  . ASP   A 1 449 ? 155.495 147.828 163.977 1.00 71.33  ? 475 ASP   A CA  1 
ATOM   3626 C C   . ASP   A 1 449 ? 155.772 147.025 165.250 1.00 66.12  ? 475 ASP   A C   1 
ATOM   3627 O O   . ASP   A 1 449 ? 155.261 147.327 166.328 1.00 73.14  ? 475 ASP   A O   1 
ATOM   3628 C CB  . ASP   A 1 449 ? 154.601 149.039 164.271 1.00 71.35  ? 475 ASP   A CB  1 
ATOM   3629 C CG  . ASP   A 1 449 ? 155.307 150.108 165.084 1.00 85.42  ? 475 ASP   A CG  1 
ATOM   3630 O OD1 . ASP   A 1 449 ? 156.483 149.906 165.456 1.00 90.46  ? 475 ASP   A OD1 1 
ATOM   3631 O OD2 . ASP   A 1 449 ? 154.685 151.159 165.347 1.00 88.52  ? 475 ASP   A OD2 1 
ATOM   3632 N N   . ARG   A 1 450 ? 156.597 145.994 165.104 1.00 57.91  ? 476 ARG   A N   1 
ATOM   3633 C CA  . ARG   A 1 450 ? 157.083 145.173 166.209 1.00 63.00  ? 476 ARG   A CA  1 
ATOM   3634 C C   . ARG   A 1 450 ? 158.592 145.364 166.345 1.00 69.43  ? 476 ARG   A C   1 
ATOM   3635 O O   . ARG   A 1 450 ? 159.207 146.159 165.631 1.00 71.30  ? 476 ARG   A O   1 
ATOM   3636 C CB  . ARG   A 1 450 ? 156.747 143.694 165.989 1.00 64.53  ? 476 ARG   A CB  1 
ATOM   3637 C CG  . ARG   A 1 450 ? 155.268 143.371 165.888 1.00 68.41  ? 476 ARG   A CG  1 
ATOM   3638 C CD  . ARG   A 1 450 ? 155.058 141.895 165.561 1.00 72.34  ? 476 ARG   A CD  1 
ATOM   3639 N NE  . ARG   A 1 450 ? 153.741 141.624 164.991 1.00 76.46  ? 476 ARG   A NE  1 
ATOM   3640 C CZ  . ARG   A 1 450 ? 152.626 141.445 165.688 1.00 78.06  ? 476 ARG   A CZ  1 
ATOM   3641 N NH1 . ARG   A 1 450 ? 152.606 141.529 167.009 1.00 81.51  ? 476 ARG   A NH1 1 
ATOM   3642 N NH2 . ARG   A 1 450 ? 151.496 141.179 165.041 1.00 77.05  ? 476 ARG   A NH2 1 
ATOM   3643 N N   . PHE   A 1 451 ? 159.189 144.628 167.279 1.00 67.80  ? 477 PHE   A N   1 
ATOM   3644 C CA  . PHE   A 1 451 ? 160.639 144.610 167.396 1.00 60.91  ? 477 PHE   A CA  1 
ATOM   3645 C C   . PHE   A 1 451 ? 161.262 144.034 166.132 1.00 58.43  ? 477 PHE   A C   1 
ATOM   3646 O O   . PHE   A 1 451 ? 160.730 143.099 165.527 1.00 59.43  ? 477 PHE   A O   1 
ATOM   3647 C CB  . PHE   A 1 451 ? 161.075 143.772 168.596 1.00 63.13  ? 477 PHE   A CB  1 
ATOM   3648 C CG  . PHE   A 1 451 ? 160.665 144.334 169.924 1.00 65.53  ? 477 PHE   A CG  1 
ATOM   3649 C CD1 . PHE   A 1 451 ? 159.455 143.988 170.491 1.00 68.41  ? 477 PHE   A CD1 1 
ATOM   3650 C CD2 . PHE   A 1 451 ? 161.503 145.186 170.618 1.00 67.79  ? 477 PHE   A CD2 1 
ATOM   3651 C CE1 . PHE   A 1 451 ? 159.083 144.495 171.716 1.00 72.77  ? 477 PHE   A CE1 1 
ATOM   3652 C CE2 . PHE   A 1 451 ? 161.134 145.694 171.844 1.00 69.71  ? 477 PHE   A CE2 1 
ATOM   3653 C CZ  . PHE   A 1 451 ? 159.926 145.347 172.394 1.00 72.04  ? 477 PHE   A CZ  1 
ATOM   3654 N N   . GLN   A 1 452 ? 162.397 144.596 165.733 1.00 54.59  ? 478 GLN   A N   1 
ATOM   3655 C CA  . GLN   A 1 452 ? 163.175 144.023 164.644 1.00 52.01  ? 478 GLN   A CA  1 
ATOM   3656 C C   . GLN   A 1 452 ? 163.787 142.709 165.109 1.00 57.88  ? 478 GLN   A C   1 
ATOM   3657 O O   . GLN   A 1 452 ? 164.493 142.675 166.122 1.00 63.40  ? 478 GLN   A O   1 
ATOM   3658 C CB  . GLN   A 1 452 ? 164.270 144.992 164.205 1.00 51.56  ? 478 GLN   A CB  1 
ATOM   3659 C CG  . GLN   A 1 452 ? 163.787 146.345 163.717 1.00 51.13  ? 478 GLN   A CG  1 
ATOM   3660 C CD  . GLN   A 1 452 ? 163.172 146.287 162.342 1.00 53.42  ? 478 GLN   A CD  1 
ATOM   3661 O OE1 . GLN   A 1 452 ? 162.943 145.210 161.794 1.00 60.76  ? 478 GLN   A OE1 1 
ATOM   3662 N NE2 . GLN   A 1 452 ? 162.903 147.452 161.769 1.00 56.98  ? 478 GLN   A NE2 1 
ATOM   3663 N N   . GLN   A 1 453 ? 163.521 141.630 164.374 1.00 59.34  ? 479 GLN   A N   1 
ATOM   3664 C CA  . GLN   A 1 453 ? 164.050 140.317 164.708 1.00 59.00  ? 479 GLN   A CA  1 
ATOM   3665 C C   . GLN   A 1 453 ? 164.519 139.625 163.439 1.00 58.29  ? 479 GLN   A C   1 
ATOM   3666 O O   . GLN   A 1 453 ? 164.094 139.956 162.331 1.00 62.43  ? 479 GLN   A O   1 
ATOM   3667 C CB  . GLN   A 1 453 ? 163.009 139.449 165.429 1.00 54.16  ? 479 GLN   A CB  1 
ATOM   3668 C CG  . GLN   A 1 453 ? 161.718 139.218 164.653 1.00 57.53  ? 479 GLN   A CG  1 
ATOM   3669 C CD  . GLN   A 1 453 ? 160.823 138.197 165.311 1.00 66.54  ? 479 GLN   A CD  1 
ATOM   3670 O OE1 . GLN   A 1 453 ? 159.693 138.499 165.691 1.00 71.71  ? 479 GLN   A OE1 1 
ATOM   3671 N NE2 . GLN   A 1 453 ? 161.319 136.973 165.440 1.00 69.13  ? 479 GLN   A NE2 1 
ATOM   3672 N N   . ARG   A 1 454 ? 165.405 138.651 163.618 1.00 54.86  ? 480 ARG   A N   1 
ATOM   3673 C CA  . ARG   A 1 454 ? 165.873 137.864 162.490 1.00 53.29  ? 480 ARG   A CA  1 
ATOM   3674 C C   . ARG   A 1 454 ? 164.732 137.041 161.905 1.00 62.08  ? 480 ARG   A C   1 
ATOM   3675 O O   . ARG   A 1 454 ? 163.855 136.555 162.624 1.00 68.45  ? 480 ARG   A O   1 
ATOM   3676 C CB  . ARG   A 1 454 ? 167.016 136.947 162.916 1.00 54.27  ? 480 ARG   A CB  1 
ATOM   3677 C CG  . ARG   A 1 454 ? 168.320 137.663 163.184 1.00 59.00  ? 480 ARG   A CG  1 
ATOM   3678 C CD  . ARG   A 1 454 ? 169.385 136.691 163.644 1.00 64.71  ? 480 ARG   A CD  1 
ATOM   3679 N NE  . ARG   A 1 454 ? 170.709 137.300 163.686 1.00 58.51  ? 480 ARG   A NE  1 
ATOM   3680 C CZ  . ARG   A 1 454 ? 171.175 138.048 164.677 1.00 63.73  ? 480 ARG   A CZ  1 
ATOM   3681 N NH1 . ARG   A 1 454 ? 170.445 138.324 165.747 1.00 67.97  ? 480 ARG   A NH1 1 
ATOM   3682 N NH2 . ARG   A 1 454 ? 172.408 138.535 164.593 1.00 62.51  ? 480 ARG   A NH2 1 
ATOM   3683 N N   . ILE   A 1 455 ? 164.757 136.889 160.582 1.00 56.63  ? 481 ILE   A N   1 
ATOM   3684 C CA  . ILE   A 1 455 ? 163.761 136.101 159.857 1.00 56.26  ? 481 ILE   A CA  1 
ATOM   3685 C C   . ILE   A 1 455 ? 164.361 134.761 159.444 1.00 58.20  ? 481 ILE   A C   1 
ATOM   3686 O O   . ILE   A 1 455 ? 163.635 133.773 159.290 1.00 62.02  ? 481 ILE   A O   1 
ATOM   3687 C CB  . ILE   A 1 455 ? 163.207 136.873 158.639 1.00 57.79  ? 481 ILE   A CB  1 
ATOM   3688 C CG1 . ILE   A 1 455 ? 162.281 135.980 157.808 1.00 58.87  ? 481 ILE   A CG1 1 
ATOM   3689 C CG2 . ILE   A 1 455 ? 164.331 137.442 157.770 1.00 60.06  ? 481 ILE   A CG2 1 
ATOM   3690 C CD1 . ILE   A 1 455 ? 161.322 136.745 156.917 1.00 63.26  ? 481 ILE   A CD1 1 
ATOM   3691 N N   . PHE   A 1 456 ? 165.684 134.713 159.270 1.00 56.85  ? 482 PHE   A N   1 
ATOM   3692 C CA  . PHE   A 1 456 ? 166.387 133.512 158.842 1.00 51.56  ? 482 PHE   A CA  1 
ATOM   3693 C C   . PHE   A 1 456 ? 167.548 133.224 159.781 1.00 54.23  ? 482 PHE   A C   1 
ATOM   3694 O O   . PHE   A 1 456 ? 168.111 134.129 160.399 1.00 59.00  ? 482 PHE   A O   1 
ATOM   3695 C CB  . PHE   A 1 456 ? 166.907 133.650 157.407 1.00 49.95  ? 482 PHE   A CB  1 
ATOM   3696 C CG  . PHE   A 1 456 ? 165.826 133.665 156.369 1.00 51.75  ? 482 PHE   A CG  1 
ATOM   3697 C CD1 . PHE   A 1 456 ? 165.140 132.509 156.049 1.00 58.02  ? 482 PHE   A CD1 1 
ATOM   3698 C CD2 . PHE   A 1 456 ? 165.505 134.829 155.703 1.00 57.59  ? 482 PHE   A CD2 1 
ATOM   3699 C CE1 . PHE   A 1 456 ? 164.149 132.520 155.092 1.00 61.72  ? 482 PHE   A CE1 1 
ATOM   3700 C CE2 . PHE   A 1 456 ? 164.516 134.846 154.749 1.00 62.32  ? 482 PHE   A CE2 1 
ATOM   3701 C CZ  . PHE   A 1 456 ? 163.839 133.691 154.442 1.00 61.49  ? 482 PHE   A CZ  1 
ATOM   3702 N N   . ASP   A 1 457 ? 167.900 131.952 159.873 1.00 54.06  ? 483 ASP   A N   1 
ATOM   3703 C CA  . ASP   A 1 457 ? 168.981 131.515 160.746 1.00 57.45  ? 483 ASP   A CA  1 
ATOM   3704 C C   . ASP   A 1 457 ? 170.308 132.054 160.218 1.00 59.48  ? 483 ASP   A C   1 
ATOM   3705 O O   . ASP   A 1 457 ? 170.645 131.783 159.058 1.00 65.54  ? 483 ASP   A O   1 
ATOM   3706 C CB  . ASP   A 1 457 ? 169.004 129.991 160.798 1.00 60.78  ? 483 ASP   A CB  1 
ATOM   3707 C CG  . ASP   A 1 457 ? 169.674 129.456 162.043 1.00 66.30  ? 483 ASP   A CG  1 
ATOM   3708 O OD1 . ASP   A 1 457 ? 170.655 130.071 162.508 1.00 68.16  ? 483 ASP   A OD1 1 
ATOM   3709 O OD2 . ASP   A 1 457 ? 169.217 128.415 162.557 1.00 65.95  ? 483 ASP   A OD2 1 
ATOM   3710 N N   . PRO   A 1 458 ? 171.092 132.805 160.998 1.00 52.77  ? 484 PRO   A N   1 
ATOM   3711 C CA  . PRO   A 1 458 ? 172.330 133.378 160.459 1.00 51.09  ? 484 PRO   A CA  1 
ATOM   3712 C C   . PRO   A 1 458 ? 173.527 132.440 160.460 1.00 51.37  ? 484 PRO   A C   1 
ATOM   3713 O O   . PRO   A 1 458 ? 174.647 132.910 160.245 1.00 56.47  ? 484 PRO   A O   1 
ATOM   3714 C CB  . PRO   A 1 458 ? 172.575 134.569 161.395 1.00 57.17  ? 484 PRO   A CB  1 
ATOM   3715 C CG  . PRO   A 1 458 ? 172.072 134.109 162.686 1.00 65.14  ? 484 PRO   A CG  1 
ATOM   3716 C CD  . PRO   A 1 458 ? 170.869 133.258 162.385 1.00 61.90  ? 484 PRO   A CD  1 
ATOM   3717 N N   . ARG   A 1 459 ? 173.323 131.139 160.683 1.00 54.77  ? 485 ARG   A N   1 
ATOM   3718 C CA  . ARG   A 1 459 ? 174.409 130.167 160.746 1.00 57.34  ? 485 ARG   A CA  1 
ATOM   3719 C C   . ARG   A 1 459 ? 174.216 129.007 159.776 1.00 62.03  ? 485 ARG   A C   1 
ATOM   3720 O O   . ARG   A 1 459 ? 174.936 128.007 159.883 1.00 69.25  ? 485 ARG   A O   1 
ATOM   3721 C CB  . ARG   A 1 459 ? 174.546 129.617 162.170 1.00 59.29  ? 485 ARG   A CB  1 
ATOM   3722 C CG  . ARG   A 1 459 ? 174.784 130.670 163.248 1.00 64.78  ? 485 ARG   A CG  1 
ATOM   3723 C CD  . ARG   A 1 459 ? 174.478 130.128 164.636 1.00 69.74  ? 485 ARG   A CD  1 
ATOM   3724 N NE  . ARG   A 1 459 ? 173.056 129.853 164.813 1.00 68.69  ? 485 ARG   A NE  1 
ATOM   3725 C CZ  . ARG   A 1 459 ? 172.501 129.413 165.934 1.00 73.63  ? 485 ARG   A CZ  1 
ATOM   3726 N NH1 . ARG   A 1 459 ? 173.217 129.184 167.024 1.00 76.06  ? 485 ARG   A NH1 1 
ATOM   3727 N NH2 . ARG   A 1 459 ? 171.190 129.196 165.965 1.00 74.17  ? 485 ARG   A NH2 1 
ATOM   3728 N N   . VAL   A 1 460 ? 173.279 129.111 158.834 1.00 56.36  ? 486 VAL   A N   1 
ATOM   3729 C CA  . VAL   A 1 460 ? 172.903 128.014 157.949 1.00 55.08  ? 486 VAL   A CA  1 
ATOM   3730 C C   . VAL   A 1 460 ? 173.304 128.373 156.527 1.00 61.63  ? 486 VAL   A C   1 
ATOM   3731 O O   . VAL   A 1 460 ? 172.915 129.429 156.013 1.00 65.60  ? 486 VAL   A O   1 
ATOM   3732 C CB  . VAL   A 1 460 ? 171.397 127.715 158.033 1.00 59.29  ? 486 VAL   A CB  1 
ATOM   3733 C CG1 . VAL   A 1 460 ? 171.012 126.636 157.031 1.00 63.08  ? 486 VAL   A CG1 1 
ATOM   3734 C CG2 . VAL   A 1 460 ? 171.013 127.296 159.447 1.00 57.68  ? 486 VAL   A CG2 1 
ATOM   3735 N N   . ASP   A 1 461 ? 174.077 127.495 155.892 1.00 63.63  ? 487 ASP   A N   1 
ATOM   3736 C CA  . ASP   A 1 461 ? 174.437 127.659 154.489 1.00 55.67  ? 487 ASP   A CA  1 
ATOM   3737 C C   . ASP   A 1 461 ? 173.205 127.406 153.632 1.00 61.05  ? 487 ASP   A C   1 
ATOM   3738 O O   . ASP   A 1 461 ? 172.759 126.263 153.494 1.00 65.56  ? 487 ASP   A O   1 
ATOM   3739 C CB  . ASP   A 1 461 ? 175.566 126.703 154.119 1.00 59.96  ? 487 ASP   A CB  1 
ATOM   3740 C CG  . ASP   A 1 461 ? 176.086 126.928 152.714 1.00 70.77  ? 487 ASP   A CG  1 
ATOM   3741 O OD1 . ASP   A 1 461 ? 175.675 127.916 152.070 1.00 75.96  ? 487 ASP   A OD1 1 
ATOM   3742 O OD2 . ASP   A 1 461 ? 176.912 126.114 152.250 1.00 73.56  ? 487 ASP   A OD2 1 
ATOM   3743 N N   . ILE   A 1 462 ? 172.648 128.475 153.059 1.00 57.12  ? 488 ILE   A N   1 
ATOM   3744 C CA  . ILE   A 1 462 ? 171.410 128.350 152.296 1.00 54.75  ? 488 ILE   A CA  1 
ATOM   3745 C C   . ILE   A 1 462 ? 171.618 127.495 151.055 1.00 57.27  ? 488 ILE   A C   1 
ATOM   3746 O O   . ILE   A 1 462 ? 170.680 126.844 150.580 1.00 63.95  ? 488 ILE   A O   1 
ATOM   3747 C CB  . ILE   A 1 462 ? 170.864 129.746 151.929 1.00 57.47  ? 488 ILE   A CB  1 
ATOM   3748 C CG1 . ILE   A 1 462 ? 170.633 130.606 153.182 1.00 57.74  ? 488 ILE   A CG1 1 
ATOM   3749 C CG2 . ILE   A 1 462 ? 169.581 129.620 151.115 1.00 62.52  ? 488 ILE   A CG2 1 
ATOM   3750 C CD1 . ILE   A 1 462 ? 169.675 130.027 154.213 1.00 62.32  ? 488 ILE   A CD1 1 
ATOM   3751 N N   . VAL   A 1 463 ? 172.833 127.481 150.506 1.00 56.21  ? 489 VAL   A N   1 
ATOM   3752 C CA  . VAL   A 1 463 ? 173.087 126.708 149.294 1.00 60.42  ? 489 VAL   A CA  1 
ATOM   3753 C C   . VAL   A 1 463 ? 172.927 125.217 149.562 1.00 69.30  ? 489 VAL   A C   1 
ATOM   3754 O O   . VAL   A 1 463 ? 172.378 124.481 148.732 1.00 72.65  ? 489 VAL   A O   1 
ATOM   3755 C CB  . VAL   A 1 463 ? 174.484 127.036 148.738 1.00 60.56  ? 489 VAL   A CB  1 
ATOM   3756 C CG1 . VAL   A 1 463 ? 174.830 126.109 147.579 1.00 62.35  ? 489 VAL   A CG1 1 
ATOM   3757 C CG2 . VAL   A 1 463 ? 174.553 128.490 148.299 1.00 62.15  ? 489 VAL   A CG2 1 
ATOM   3758 N N   . GLN   A 1 464 ? 173.397 124.747 150.717 1.00 71.66  ? 490 GLN   A N   1 
ATOM   3759 C CA  . GLN   A 1 464 ? 173.309 123.343 151.096 1.00 69.54  ? 490 GLN   A CA  1 
ATOM   3760 C C   . GLN   A 1 464 ? 172.110 123.038 151.985 1.00 70.38  ? 490 GLN   A C   1 
ATOM   3761 O O   . GLN   A 1 464 ? 171.934 121.883 152.384 1.00 76.93  ? 490 GLN   A O   1 
ATOM   3762 C CB  . GLN   A 1 464 ? 174.593 122.913 151.813 1.00 70.05  ? 490 GLN   A CB  1 
ATOM   3763 C CG  . GLN   A 1 464 ? 175.877 123.202 151.046 1.00 74.03  ? 490 GLN   A CG  1 
ATOM   3764 C CD  . GLN   A 1 464 ? 175.933 122.507 149.703 1.00 78.31  ? 490 GLN   A CD  1 
ATOM   3765 O OE1 . GLN   A 1 464 ? 175.247 121.511 149.479 1.00 72.76  ? 490 GLN   A OE1 1 
ATOM   3766 N NE2 . GLN   A 1 464 ? 176.754 123.030 148.800 1.00 82.04  ? 490 GLN   A NE2 1 
ATOM   3767 N N   . ALA   A 1 465 ? 171.284 124.031 152.302 1.00 64.44  ? 491 ALA   A N   1 
ATOM   3768 C CA  . ALA   A 1 465 ? 170.125 123.797 153.146 1.00 60.38  ? 491 ALA   A CA  1 
ATOM   3769 C C   . ALA   A 1 465 ? 169.073 122.990 152.392 1.00 67.30  ? 491 ALA   A C   1 
ATOM   3770 O O   . ALA   A 1 465 ? 169.062 122.930 151.159 1.00 72.03  ? 491 ALA   A O   1 
ATOM   3771 C CB  . ALA   A 1 465 ? 169.535 125.123 153.622 1.00 63.68  ? 491 ALA   A CB  1 
ATOM   3772 N N   . ALA   A 1 466 ? 168.182 122.362 153.154 1.00 70.35  ? 492 ALA   A N   1 
ATOM   3773 C CA  . ALA   A 1 466 ? 167.162 121.473 152.612 1.00 71.56  ? 492 ALA   A CA  1 
ATOM   3774 C C   . ALA   A 1 466 ? 165.828 122.202 152.537 1.00 67.42  ? 492 ALA   A C   1 
ATOM   3775 O O   . ALA   A 1 466 ? 165.361 122.757 153.538 1.00 65.15  ? 492 ALA   A O   1 
ATOM   3776 C CB  . ALA   A 1 466 ? 167.026 120.218 153.473 1.00 69.51  ? 492 ALA   A CB  1 
ATOM   3777 N N   . TRP   A 1 467 ? 165.220 122.198 151.352 1.00 65.01  ? 493 TRP   A N   1 
ATOM   3778 C CA  . TRP   A 1 467 ? 163.926 122.829 151.127 1.00 64.01  ? 493 TRP   A CA  1 
ATOM   3779 C C   . TRP   A 1 467 ? 163.143 122.017 150.109 1.00 67.43  ? 493 TRP   A C   1 
ATOM   3780 O O   . TRP   A 1 467 ? 163.685 121.644 149.065 1.00 73.52  ? 493 TRP   A O   1 
ATOM   3781 C CB  . TRP   A 1 467 ? 164.084 124.271 150.632 1.00 62.27  ? 493 TRP   A CB  1 
ATOM   3782 C CG  . TRP   A 1 467 ? 162.810 124.870 150.119 1.00 65.45  ? 493 TRP   A CG  1 
ATOM   3783 C CD1 . TRP   A 1 467 ? 161.827 125.460 150.855 1.00 68.72  ? 493 TRP   A CD1 1 
ATOM   3784 C CD2 . TRP   A 1 467 ? 162.386 124.943 148.754 1.00 66.34  ? 493 TRP   A CD2 1 
ATOM   3785 N NE1 . TRP   A 1 467 ? 160.816 125.894 150.035 1.00 66.08  ? 493 TRP   A NE1 1 
ATOM   3786 C CE2 . TRP   A 1 467 ? 161.136 125.589 148.739 1.00 62.73  ? 493 TRP   A CE2 1 
ATOM   3787 C CE3 . TRP   A 1 467 ? 162.942 124.523 147.543 1.00 70.03  ? 493 TRP   A CE3 1 
ATOM   3788 C CZ2 . TRP   A 1 467 ? 160.430 125.819 147.564 1.00 70.39  ? 493 TRP   A CZ2 1 
ATOM   3789 C CZ3 . TRP   A 1 467 ? 162.242 124.757 146.376 1.00 72.41  ? 493 TRP   A CZ3 1 
ATOM   3790 C CH2 . TRP   A 1 467 ? 160.999 125.400 146.395 1.00 74.65  ? 493 TRP   A CH2 1 
ATOM   3791 N N   . SER   A 1 468 ? 161.882 121.735 150.422 1.00 68.49  ? 494 SER   A N   1 
ATOM   3792 C CA  . SER   A 1 468 ? 160.958 121.093 149.501 1.00 68.94  ? 494 SER   A CA  1 
ATOM   3793 C C   . SER   A 1 468 ? 159.597 121.762 149.626 1.00 67.80  ? 494 SER   A C   1 
ATOM   3794 O O   . SER   A 1 468 ? 159.297 122.358 150.668 1.00 73.55  ? 494 SER   A O   1 
ATOM   3795 C CB  . SER   A 1 468 ? 160.827 119.587 149.774 1.00 75.68  ? 494 SER   A CB  1 
ATOM   3796 O OG  . SER   A 1 468 ? 160.376 119.345 151.094 1.00 81.78  ? 494 SER   A OG  1 
ATOM   3797 N N   . PRO   A 1 469 ? 158.759 121.699 148.583 1.00 60.15  ? 495 PRO   A N   1 
ATOM   3798 C CA  . PRO   A 1 469 ? 157.495 122.457 148.624 1.00 61.13  ? 495 PRO   A CA  1 
ATOM   3799 C C   . PRO   A 1 469 ? 156.553 122.052 149.743 1.00 75.91  ? 495 PRO   A C   1 
ATOM   3800 O O   . PRO   A 1 469 ? 155.821 122.909 150.253 1.00 80.91  ? 495 PRO   A O   1 
ATOM   3801 C CB  . PRO   A 1 469 ? 156.870 122.177 147.250 1.00 61.06  ? 495 PRO   A CB  1 
ATOM   3802 C CG  . PRO   A 1 469 ? 157.971 121.695 146.404 1.00 61.71  ? 495 PRO   A CG  1 
ATOM   3803 C CD  . PRO   A 1 469 ? 158.905 120.974 147.308 1.00 63.77  ? 495 PRO   A CD  1 
ATOM   3804 N N   . PHE   A 1 470 ? 156.535 120.776 150.131 1.00 80.82  ? 496 PHE   A N   1 
ATOM   3805 C CA  . PHE   A 1 470 ? 155.526 120.237 151.037 1.00 75.17  ? 496 PHE   A CA  1 
ATOM   3806 C C   . PHE   A 1 470 ? 156.058 119.940 152.435 1.00 74.12  ? 496 PHE   A C   1 
ATOM   3807 O O   . PHE   A 1 470 ? 155.365 119.274 153.212 1.00 78.89  ? 496 PHE   A O   1 
ATOM   3808 C CB  . PHE   A 1 470 ? 154.916 118.968 150.439 1.00 77.86  ? 496 PHE   A CB  1 
ATOM   3809 C CG  . PHE   A 1 470 ? 154.492 119.118 149.006 1.00 81.64  ? 496 PHE   A CG  1 
ATOM   3810 C CD1 . PHE   A 1 470 ? 153.509 120.025 148.651 1.00 81.66  ? 496 PHE   A CD1 1 
ATOM   3811 C CD2 . PHE   A 1 470 ? 155.071 118.346 148.015 1.00 75.39  ? 496 PHE   A CD2 1 
ATOM   3812 C CE1 . PHE   A 1 470 ? 153.118 120.163 147.335 1.00 79.56  ? 496 PHE   A CE1 1 
ATOM   3813 C CE2 . PHE   A 1 470 ? 154.683 118.480 146.698 1.00 76.75  ? 496 PHE   A CE2 1 
ATOM   3814 C CZ  . PHE   A 1 470 ? 153.706 119.389 146.358 1.00 79.47  ? 496 PHE   A CZ  1 
ATOM   3815 N N   . GLN   A 1 471 ? 157.263 120.403 152.775 1.00 75.23  ? 497 GLN   A N   1 
ATOM   3816 C CA  . GLN   A 1 471 ? 157.857 120.172 154.087 1.00 77.22  ? 497 GLN   A CA  1 
ATOM   3817 C C   . GLN   A 1 471 ? 158.331 121.492 154.676 1.00 76.42  ? 497 GLN   A C   1 
ATOM   3818 O O   . GLN   A 1 471 ? 158.924 122.318 153.976 1.00 81.30  ? 497 GLN   A O   1 
ATOM   3819 C CB  . GLN   A 1 471 ? 159.028 119.188 154.007 1.00 83.65  ? 497 GLN   A CB  1 
ATOM   3820 C CG  . GLN   A 1 471 ? 158.672 117.857 153.365 1.00 91.06  ? 497 GLN   A CG  1 
ATOM   3821 C CD  . GLN   A 1 471 ? 159.831 116.884 153.365 1.00 95.42  ? 497 GLN   A CD  1 
ATOM   3822 O OE1 . GLN   A 1 471 ? 160.923 117.202 153.834 1.00 92.62  ? 497 GLN   A OE1 1 
ATOM   3823 N NE2 . GLN   A 1 471 ? 159.599 115.687 152.839 1.00 95.97  ? 497 GLN   A NE2 1 
ATOM   3824 N N   . ARG   A 1 472 ? 158.068 121.679 155.966 1.00 71.16  ? 498 ARG   A N   1 
ATOM   3825 C CA  . ARG   A 1 472 ? 158.396 122.932 156.628 1.00 75.41  ? 498 ARG   A CA  1 
ATOM   3826 C C   . ARG   A 1 472 ? 159.905 123.103 156.743 1.00 81.37  ? 498 ARG   A C   1 
ATOM   3827 O O   . ARG   A 1 472 ? 160.636 122.155 157.044 1.00 81.58  ? 498 ARG   A O   1 
ATOM   3828 C CB  . ARG   A 1 472 ? 157.756 122.975 158.015 1.00 78.84  ? 498 ARG   A CB  1 
ATOM   3829 C CG  . ARG   A 1 472 ? 157.820 124.334 158.695 1.00 86.62  ? 498 ARG   A CG  1 
ATOM   3830 C CD  . ARG   A 1 472 ? 157.197 124.296 160.083 1.00 95.72  ? 498 ARG   A CD  1 
ATOM   3831 N NE  . ARG   A 1 472 ? 155.773 123.979 160.044 1.00 100.91 ? 498 ARG   A NE  1 
ATOM   3832 C CZ  . ARG   A 1 472 ? 154.998 123.830 161.112 1.00 104.25 ? 498 ARG   A CZ  1 
ATOM   3833 N NH1 . ARG   A 1 472 ? 155.474 123.956 162.342 1.00 102.98 ? 498 ARG   A NH1 1 
ATOM   3834 N NH2 . ARG   A 1 472 ? 153.710 123.547 160.942 1.00 101.19 ? 498 ARG   A NH2 1 
ATOM   3835 N N   . THR   A 1 473 ? 160.369 124.326 156.499 1.00 77.98  ? 499 THR   A N   1 
ATOM   3836 C CA  . THR   A 1 473 ? 161.783 124.646 156.617 1.00 66.11  ? 499 THR   A CA  1 
ATOM   3837 C C   . THR   A 1 473 ? 162.185 124.761 158.081 1.00 66.53  ? 499 THR   A C   1 
ATOM   3838 O O   . THR   A 1 473 ? 161.426 125.268 158.911 1.00 71.75  ? 499 THR   A O   1 
ATOM   3839 C CB  . THR   A 1 473 ? 162.092 125.952 155.889 1.00 61.33  ? 499 THR   A CB  1 
ATOM   3840 O OG1 . THR   A 1 473 ? 161.146 126.953 156.282 1.00 63.42  ? 499 THR   A OG1 1 
ATOM   3841 C CG2 . THR   A 1 473 ? 162.020 125.757 154.391 1.00 65.47  ? 499 THR   A CG2 1 
ATOM   3842 N N   . SER   A 1 474 ? 163.392 124.291 158.390 1.00 63.85  ? 500 SER   A N   1 
ATOM   3843 C CA  . SER   A 1 474 ? 163.940 124.341 159.738 1.00 61.78  ? 500 SER   A CA  1 
ATOM   3844 C C   . SER   A 1 474 ? 164.832 125.552 159.984 1.00 64.36  ? 500 SER   A C   1 
ATOM   3845 O O   . SER   A 1 474 ? 165.402 125.664 161.074 1.00 66.06  ? 500 SER   A O   1 
ATOM   3846 C CB  . SER   A 1 474 ? 164.731 123.063 160.027 1.00 69.39  ? 500 SER   A CB  1 
ATOM   3847 O OG  . SER   A 1 474 ? 165.809 122.915 159.119 1.00 73.93  ? 500 SER   A OG  1 
ATOM   3848 N N   . TRP   A 1 475 ? 164.975 126.452 159.010 1.00 62.28  ? 501 TRP   A N   1 
ATOM   3849 C CA  . TRP   A 1 475 ? 165.817 127.640 159.121 1.00 53.38  ? 501 TRP   A CA  1 
ATOM   3850 C C   . TRP   A 1 475 ? 165.010 128.907 158.851 1.00 53.02  ? 501 TRP   A C   1 
ATOM   3851 O O   . TRP   A 1 475 ? 165.470 129.833 158.181 1.00 60.09  ? 501 TRP   A O   1 
ATOM   3852 C CB  . TRP   A 1 475 ? 167.029 127.536 158.191 1.00 52.38  ? 501 TRP   A CB  1 
ATOM   3853 C CG  . TRP   A 1 475 ? 166.740 126.979 156.830 1.00 53.47  ? 501 TRP   A CG  1 
ATOM   3854 C CD1 . TRP   A 1 475 ? 166.726 125.664 156.475 1.00 60.32  ? 501 TRP   A CD1 1 
ATOM   3855 C CD2 . TRP   A 1 475 ? 166.440 127.717 155.640 1.00 52.94  ? 501 TRP   A CD2 1 
ATOM   3856 N NE1 . TRP   A 1 475 ? 166.428 125.536 155.143 1.00 65.70  ? 501 TRP   A NE1 1 
ATOM   3857 C CE2 . TRP   A 1 475 ? 166.250 126.782 154.607 1.00 56.99  ? 501 TRP   A CE2 1 
ATOM   3858 C CE3 . TRP   A 1 475 ? 166.308 129.077 155.349 1.00 57.75  ? 501 TRP   A CE3 1 
ATOM   3859 C CZ2 . TRP   A 1 475 ? 165.933 127.161 153.308 1.00 57.64  ? 501 TRP   A CZ2 1 
ATOM   3860 C CZ3 . TRP   A 1 475 ? 165.995 129.450 154.058 1.00 55.93  ? 501 TRP   A CZ3 1 
ATOM   3861 C CH2 . TRP   A 1 475 ? 165.811 128.497 153.055 1.00 55.29  ? 501 TRP   A CH2 1 
ATOM   3862 N N   . VAL   A 1 476 ? 163.786 128.953 159.371 1.00 52.66  ? 502 VAL   A N   1 
ATOM   3863 C CA  . VAL   A 1 476 ? 162.967 130.159 159.399 1.00 53.50  ? 502 VAL   A CA  1 
ATOM   3864 C C   . VAL   A 1 476 ? 162.591 130.414 160.850 1.00 59.97  ? 502 VAL   A C   1 
ATOM   3865 O O   . VAL   A 1 476 ? 161.896 129.599 161.469 1.00 64.30  ? 502 VAL   A O   1 
ATOM   3866 C CB  . VAL   A 1 476 ? 161.716 130.030 158.516 1.00 56.50  ? 502 VAL   A CB  1 
ATOM   3867 C CG1 . VAL   A 1 476 ? 160.844 131.269 158.644 1.00 58.62  ? 502 VAL   A CG1 1 
ATOM   3868 C CG2 . VAL   A 1 476 ? 162.111 129.800 157.063 1.00 63.00  ? 502 VAL   A CG2 1 
ATOM   3869 N N   . GLN   A 1 477 ? 163.046 131.538 161.389 1.00 60.34  ? 503 GLN   A N   1 
ATOM   3870 C CA  . GLN   A 1 477 ? 162.829 131.824 162.797 1.00 62.21  ? 503 GLN   A CA  1 
ATOM   3871 C C   . GLN   A 1 477 ? 161.346 132.102 163.057 1.00 64.82  ? 503 GLN   A C   1 
ATOM   3872 O O   . GLN   A 1 477 ? 160.696 132.779 162.256 1.00 69.98  ? 503 GLN   A O   1 
ATOM   3873 C CB  . GLN   A 1 477 ? 163.662 133.028 163.232 1.00 62.77  ? 503 GLN   A CB  1 
ATOM   3874 C CG  . GLN   A 1 477 ? 165.163 132.825 163.139 1.00 60.02  ? 503 GLN   A CG  1 
ATOM   3875 C CD  . GLN   A 1 477 ? 165.693 131.888 164.201 1.00 64.36  ? 503 GLN   A CD  1 
ATOM   3876 O OE1 . GLN   A 1 477 ? 164.936 131.347 165.004 1.00 70.05  ? 503 GLN   A OE1 1 
ATOM   3877 N NE2 . GLN   A 1 477 ? 167.003 131.692 164.212 1.00 63.25  ? 503 GLN   A NE2 1 
ATOM   3878 N N   . PRO   A 1 478 ? 160.780 131.609 164.163 1.00 59.07  ? 504 PRO   A N   1 
ATOM   3879 C CA  . PRO   A 1 478 ? 159.372 131.908 164.444 1.00 60.95  ? 504 PRO   A CA  1 
ATOM   3880 C C   . PRO   A 1 478 ? 159.162 133.370 164.801 1.00 60.79  ? 504 PRO   A C   1 
ATOM   3881 O O   . PRO   A 1 478 ? 160.043 134.035 165.350 1.00 62.32  ? 504 PRO   A O   1 
ATOM   3882 C CB  . PRO   A 1 478 ? 159.047 130.997 165.630 1.00 62.45  ? 504 PRO   A CB  1 
ATOM   3883 C CG  . PRO   A 1 478 ? 160.335 130.823 166.317 1.00 60.78  ? 504 PRO   A CG  1 
ATOM   3884 C CD  . PRO   A 1 478 ? 161.370 130.789 165.238 1.00 59.18  ? 504 PRO   A CD  1 
ATOM   3885 N N   . LEU   A 1 479 ? 157.968 133.866 164.488 1.00 65.56  ? 505 LEU   A N   1 
ATOM   3886 C CA  . LEU   A 1 479 ? 157.580 135.218 164.868 1.00 59.97  ? 505 LEU   A CA  1 
ATOM   3887 C C   . LEU   A 1 479 ? 157.209 135.222 166.343 1.00 62.94  ? 505 LEU   A C   1 
ATOM   3888 O O   . LEU   A 1 479 ? 156.345 134.451 166.774 1.00 71.79  ? 505 LEU   A O   1 
ATOM   3889 C CB  . LEU   A 1 479 ? 156.413 135.701 164.011 1.00 62.83  ? 505 LEU   A CB  1 
ATOM   3890 C CG  . LEU   A 1 479 ? 156.148 137.210 163.966 1.00 68.49  ? 505 LEU   A CG  1 
ATOM   3891 C CD1 . LEU   A 1 479 ? 155.439 137.567 162.668 1.00 69.60  ? 505 LEU   A CD1 1 
ATOM   3892 C CD2 . LEU   A 1 479 ? 155.338 137.690 165.164 1.00 69.40  ? 505 LEU   A CD2 1 
ATOM   3893 N N   . LEU   A 1 480 ? 157.860 136.087 167.115 1.00 62.25  ? 506 LEU   A N   1 
ATOM   3894 C CA  . LEU   A 1 480 ? 157.649 136.158 168.558 1.00 67.44  ? 506 LEU   A CA  1 
ATOM   3895 C C   . LEU   A 1 480 ? 156.487 137.103 168.830 1.00 71.97  ? 506 LEU   A C   1 
ATOM   3896 O O   . LEU   A 1 480 ? 156.655 138.320 168.916 1.00 78.22  ? 506 LEU   A O   1 
ATOM   3897 C CB  . LEU   A 1 480 ? 158.921 136.615 169.262 1.00 72.47  ? 506 LEU   A CB  1 
ATOM   3898 C CG  . LEU   A 1 480 ? 160.167 135.754 169.042 1.00 73.25  ? 506 LEU   A CG  1 
ATOM   3899 C CD1 . LEU   A 1 480 ? 161.379 136.405 169.684 1.00 68.54  ? 506 LEU   A CD1 1 
ATOM   3900 C CD2 . LEU   A 1 480 ? 159.962 134.348 169.585 1.00 72.75  ? 506 LEU   A CD2 1 
ATOM   3901 N N   . MET   A 1 481 ? 155.290 136.533 168.972 1.00 73.50  ? 507 MET   A N   1 
ATOM   3902 C CA  . MET   A 1 481 ? 154.116 137.317 169.332 1.00 75.78  ? 507 MET   A CA  1 
ATOM   3903 C C   . MET   A 1 481 ? 154.004 137.560 170.831 1.00 74.50  ? 507 MET   A C   1 
ATOM   3904 O O   . MET   A 1 481 ? 153.137 138.334 171.250 1.00 78.04  ? 507 MET   A O   1 
ATOM   3905 C CB  . MET   A 1 481 ? 152.845 136.626 168.831 1.00 78.53  ? 507 MET   A CB  1 
ATOM   3906 C CG  . MET   A 1 481 ? 152.726 136.587 167.316 1.00 76.69  ? 507 MET   A CG  1 
ATOM   3907 S SD  . MET   A 1 481 ? 151.103 136.087 166.715 1.00 86.87  ? 507 MET   A SD  1 
ATOM   3908 C CE  . MET   A 1 481 ? 150.117 137.518 167.151 1.00 85.82  ? 507 MET   A CE  1 
ATOM   3909 N N   . ASP   A 1 482 ? 154.856 136.932 171.646 1.00 77.18  ? 508 ASP   A N   1 
ATOM   3910 C CA  . ASP   A 1 482 ? 154.869 137.223 173.075 1.00 78.44  ? 508 ASP   A CA  1 
ATOM   3911 C C   . ASP   A 1 482 ? 155.297 138.654 173.363 1.00 76.23  ? 508 ASP   A C   1 
ATOM   3912 O O   . ASP   A 1 482 ? 154.968 139.183 174.429 1.00 75.77  ? 508 ASP   A O   1 
ATOM   3913 C CB  . ASP   A 1 482 ? 155.799 136.251 173.801 1.00 85.42  ? 508 ASP   A CB  1 
ATOM   3914 C CG  . ASP   A 1 482 ? 155.368 134.807 173.645 1.00 100.11 ? 508 ASP   A CG  1 
ATOM   3915 O OD1 . ASP   A 1 482 ? 154.334 134.561 172.988 1.00 99.71  ? 508 ASP   A OD1 1 
ATOM   3916 O OD2 . ASP   A 1 482 ? 156.063 133.917 174.178 1.00 108.83 ? 508 ASP   A OD2 1 
ATOM   3917 N N   . LEU   A 1 483 ? 156.019 139.286 172.441 1.00 76.76  ? 509 LEU   A N   1 
ATOM   3918 C CA  . LEU   A 1 483 ? 156.401 140.687 172.541 1.00 79.11  ? 509 LEU   A CA  1 
ATOM   3919 C C   . LEU   A 1 483 ? 155.399 141.616 171.855 1.00 78.62  ? 509 LEU   A C   1 
ATOM   3920 O O   . LEU   A 1 483 ? 155.685 142.806 171.693 1.00 75.50  ? 509 LEU   A O   1 
ATOM   3921 C CB  . LEU   A 1 483 ? 157.802 140.891 171.946 1.00 75.53  ? 509 LEU   A CB  1 
ATOM   3922 C CG  . LEU   A 1 483 ? 159.025 140.284 172.657 1.00 69.81  ? 509 LEU   A CG  1 
ATOM   3923 C CD1 . LEU   A 1 483 ? 159.116 140.752 174.103 1.00 73.01  ? 509 LEU   A CD1 1 
ATOM   3924 C CD2 . LEU   A 1 483 ? 159.050 138.764 172.594 1.00 67.76  ? 509 LEU   A CD2 1 
ATOM   3925 N N   . SER   A 1 484 ? 154.241 141.098 171.441 1.00 77.01  ? 510 SER   A N   1 
ATOM   3926 C CA  . SER   A 1 484 ? 153.222 141.940 170.817 1.00 72.50  ? 510 SER   A CA  1 
ATOM   3927 C C   . SER   A 1 484 ? 152.739 143.085 171.702 1.00 75.08  ? 510 SER   A C   1 
ATOM   3928 O O   . SER   A 1 484 ? 152.723 144.232 171.220 1.00 79.32  ? 510 SER   A O   1 
ATOM   3929 C CB  . SER   A 1 484 ? 152.044 141.066 170.378 1.00 79.43  ? 510 SER   A CB  1 
ATOM   3930 O OG  . SER   A 1 484 ? 152.446 140.129 169.395 1.00 86.90  ? 510 SER   A OG  1 
ATOM   3931 N N   . PRO   A 1 485 ? 152.328 142.875 172.962 1.00 73.28  ? 511 PRO   A N   1 
ATOM   3932 C CA  . PRO   A 1 485 ? 151.764 144.003 173.732 1.00 76.89  ? 511 PRO   A CA  1 
ATOM   3933 C C   . PRO   A 1 485 ? 152.734 145.153 173.938 1.00 80.19  ? 511 PRO   A C   1 
ATOM   3934 O O   . PRO   A 1 485 ? 152.289 146.301 174.104 1.00 84.05  ? 511 PRO   A O   1 
ATOM   3935 C CB  . PRO   A 1 485 ? 151.358 143.361 175.065 1.00 74.33  ? 511 PRO   A CB  1 
ATOM   3936 C CG  . PRO   A 1 485 ? 152.107 142.103 175.140 1.00 72.63  ? 511 PRO   A CG  1 
ATOM   3937 C CD  . PRO   A 1 485 ? 152.274 141.625 173.743 1.00 70.27  ? 511 PRO   A CD  1 
ATOM   3938 N N   . TRP   A 1 486 ? 154.045 144.897 173.848 1.00 73.74  ? 512 TRP   A N   1 
ATOM   3939 C CA  . TRP   A 1 486 ? 155.032 145.967 173.940 1.00 77.38  ? 512 TRP   A CA  1 
ATOM   3940 C C   . TRP   A 1 486 ? 154.801 147.061 172.907 1.00 78.16  ? 512 TRP   A C   1 
ATOM   3941 O O   . TRP   A 1 486 ? 155.224 148.199 173.134 1.00 81.31  ? 512 TRP   A O   1 
ATOM   3942 C CB  . TRP   A 1 486 ? 156.442 145.409 173.759 1.00 76.19  ? 512 TRP   A CB  1 
ATOM   3943 C CG  . TRP   A 1 486 ? 157.057 144.829 174.993 1.00 71.78  ? 512 TRP   A CG  1 
ATOM   3944 C CD1 . TRP   A 1 486 ? 157.085 143.516 175.355 1.00 72.15  ? 512 TRP   A CD1 1 
ATOM   3945 C CD2 . TRP   A 1 486 ? 157.756 145.542 176.018 1.00 63.60  ? 512 TRP   A CD2 1 
ATOM   3946 N NE1 . TRP   A 1 486 ? 157.752 143.367 176.544 1.00 68.17  ? 512 TRP   A NE1 1 
ATOM   3947 C CE2 . TRP   A 1 486 ? 158.175 144.598 176.972 1.00 64.42  ? 512 TRP   A CE2 1 
ATOM   3948 C CE3 . TRP   A 1 486 ? 158.067 146.888 176.221 1.00 66.37  ? 512 TRP   A CE3 1 
ATOM   3949 C CZ2 . TRP   A 1 486 ? 158.883 144.956 178.114 1.00 67.87  ? 512 TRP   A CZ2 1 
ATOM   3950 C CZ3 . TRP   A 1 486 ? 158.769 147.241 177.353 1.00 67.80  ? 512 TRP   A CZ3 1 
ATOM   3951 C CH2 . TRP   A 1 486 ? 159.171 146.279 178.285 1.00 65.79  ? 512 TRP   A CH2 1 
ATOM   3952 N N   . ARG   A 1 487 ? 154.087 146.759 171.813 1.00 73.64  ? 513 ARG   A N   1 
ATOM   3953 C CA  . ARG   A 1 487 ? 153.806 147.762 170.791 1.00 72.68  ? 513 ARG   A CA  1 
ATOM   3954 C C   . ARG   A 1 487 ? 153.111 148.984 171.367 1.00 79.24  ? 513 ARG   A C   1 
ATOM   3955 O O   . ARG   A 1 487 ? 153.205 150.073 170.790 1.00 83.37  ? 513 ARG   A O   1 
ATOM   3956 C CB  . ARG   A 1 487 ? 152.935 147.166 169.689 1.00 74.85  ? 513 ARG   A CB  1 
ATOM   3957 C CG  . ARG   A 1 487 ? 153.630 146.161 168.809 1.00 75.25  ? 513 ARG   A CG  1 
ATOM   3958 C CD  . ARG   A 1 487 ? 152.764 145.814 167.614 1.00 75.12  ? 513 ARG   A CD  1 
ATOM   3959 N NE  . ARG   A 1 487 ? 151.489 145.230 168.015 1.00 80.26  ? 513 ARG   A NE  1 
ATOM   3960 C CZ  . ARG   A 1 487 ? 150.496 144.933 167.187 1.00 83.75  ? 513 ARG   A CZ  1 
ATOM   3961 N NH1 . ARG   A 1 487 ? 150.581 145.159 165.886 1.00 79.72  ? 513 ARG   A NH1 1 
ATOM   3962 N NH2 . ARG   A 1 487 ? 149.384 144.393 167.678 1.00 84.02  ? 513 ARG   A NH2 1 
ATOM   3963 N N   . ALA   A 1 488 ? 152.401 148.836 172.487 1.00 78.63  ? 514 ALA   A N   1 
ATOM   3964 C CA  . ALA   A 1 488 ? 151.902 150.023 173.169 1.00 78.13  ? 514 ALA   A CA  1 
ATOM   3965 C C   . ALA   A 1 488 ? 153.060 150.901 173.632 1.00 86.10  ? 514 ALA   A C   1 
ATOM   3966 O O   . ALA   A 1 488 ? 153.275 152.002 173.105 1.00 86.74  ? 514 ALA   A O   1 
ATOM   3967 C CB  . ALA   A 1 488 ? 151.019 149.616 174.349 1.00 80.39  ? 514 ALA   A CB  1 
ATOM   3968 N N   . LYS   A 1 489 ? 153.874 150.381 174.558 1.00 89.34  ? 515 LYS   A N   1 
ATOM   3969 C CA  . LYS   A 1 489 ? 154.851 151.218 175.252 1.00 87.53  ? 515 LYS   A CA  1 
ATOM   3970 C C   . LYS   A 1 489 ? 155.882 151.791 174.291 1.00 80.23  ? 515 LYS   A C   1 
ATOM   3971 O O   . LYS   A 1 489 ? 156.262 152.963 174.411 1.00 79.57  ? 515 LYS   A O   1 
ATOM   3972 C CB  . LYS   A 1 489 ? 155.545 150.424 176.358 1.00 88.01  ? 515 LYS   A CB  1 
ATOM   3973 C CG  . LYS   A 1 489 ? 154.755 150.372 177.665 1.00 95.42  ? 515 LYS   A CG  1 
ATOM   3974 C CD  . LYS   A 1 489 ? 155.536 149.732 178.820 1.00 96.55  ? 515 LYS   A CD  1 
ATOM   3975 C CE  . LYS   A 1 489 ? 156.783 150.522 179.226 1.00 91.96  ? 515 LYS   A CE  1 
ATOM   3976 N NZ  . LYS   A 1 489 ? 156.535 151.981 179.399 1.00 92.08  ? 515 LYS   A NZ  1 
ATOM   3977 N N   . LEU   A 1 490 ? 156.337 150.978 173.330 1.00 75.01  ? 516 LEU   A N   1 
ATOM   3978 C CA  . LEU   A 1 490 ? 157.312 151.443 172.348 1.00 71.72  ? 516 LEU   A CA  1 
ATOM   3979 C C   . LEU   A 1 490 ? 156.840 152.716 171.664 1.00 76.35  ? 516 LEU   A C   1 
ATOM   3980 O O   . LEU   A 1 490 ? 157.621 153.662 171.494 1.00 82.27  ? 516 LEU   A O   1 
ATOM   3981 C CB  . LEU   A 1 490 ? 157.570 150.359 171.301 1.00 71.55  ? 516 LEU   A CB  1 
ATOM   3982 C CG  . LEU   A 1 490 ? 158.114 149.001 171.749 1.00 75.02  ? 516 LEU   A CG  1 
ATOM   3983 C CD1 . LEU   A 1 490 ? 158.317 148.113 170.533 1.00 72.13  ? 516 LEU   A CD1 1 
ATOM   3984 C CD2 . LEU   A 1 490 ? 159.404 149.131 172.538 1.00 79.49  ? 516 LEU   A CD2 1 
ATOM   3985 N N   . GLN   A 1 491 ? 155.550 152.780 171.319 1.00 81.27  ? 517 GLN   A N   1 
ATOM   3986 C CA  . GLN   A 1 491 ? 155.042 153.959 170.626 1.00 81.33  ? 517 GLN   A CA  1 
ATOM   3987 C C   . GLN   A 1 491 ? 155.208 155.199 171.489 1.00 81.39  ? 517 GLN   A C   1 
ATOM   3988 O O   . GLN   A 1 491 ? 155.607 156.261 170.992 1.00 83.53  ? 517 GLN   A O   1 
ATOM   3989 C CB  . GLN   A 1 491 ? 153.576 153.756 170.243 1.00 82.79  ? 517 GLN   A CB  1 
ATOM   3990 C CG  . GLN   A 1 491 ? 153.161 154.458 168.957 1.00 82.41  ? 517 GLN   A CG  1 
ATOM   3991 C CD  . GLN   A 1 491 ? 153.127 155.968 169.087 1.00 91.38  ? 517 GLN   A CD  1 
ATOM   3992 O OE1 . GLN   A 1 491 ? 152.875 156.506 170.164 1.00 92.46  ? 517 GLN   A OE1 1 
ATOM   3993 N NE2 . GLN   A 1 491 ? 153.382 156.661 167.982 1.00 92.21  ? 517 GLN   A NE2 1 
ATOM   3994 N N   . GLU   A 1 492 ? 154.964 155.065 172.796 1.00 75.72  ? 518 GLU   A N   1 
ATOM   3995 C CA  . GLU   A 1 492 ? 155.168 156.188 173.703 1.00 79.13  ? 518 GLU   A CA  1 
ATOM   3996 C C   . GLU   A 1 492 ? 156.613 156.662 173.656 1.00 85.38  ? 518 GLU   A C   1 
ATOM   3997 O O   . GLU   A 1 492 ? 156.877 157.870 173.601 1.00 85.08  ? 518 GLU   A O   1 
ATOM   3998 C CB  . GLU   A 1 492 ? 154.777 155.788 175.125 1.00 81.54  ? 518 GLU   A CB  1 
ATOM   3999 C CG  . GLU   A 1 492 ? 154.763 156.938 176.117 1.00 87.34  ? 518 GLU   A CG  1 
ATOM   4000 C CD  . GLU   A 1 492 ? 154.279 156.514 177.489 1.00 95.79  ? 518 GLU   A CD  1 
ATOM   4001 O OE1 . GLU   A 1 492 ? 153.949 155.321 177.663 1.00 94.99  ? 518 GLU   A OE1 1 
ATOM   4002 O OE2 . GLU   A 1 492 ? 154.228 157.372 178.395 1.00 97.73  ? 518 GLU   A OE2 1 
ATOM   4003 N N   . ILE   A 1 493 ? 157.562 155.721 173.632 1.00 82.35  ? 519 ILE   A N   1 
ATOM   4004 C CA  . ILE   A 1 493 ? 158.972 156.098 173.576 1.00 69.68  ? 519 ILE   A CA  1 
ATOM   4005 C C   . ILE   A 1 493 ? 159.263 156.841 172.281 1.00 73.66  ? 519 ILE   A C   1 
ATOM   4006 O O   . ILE   A 1 493 ? 160.117 157.734 172.239 1.00 77.97  ? 519 ILE   A O   1 
ATOM   4007 C CB  . ILE   A 1 493 ? 159.871 154.857 173.741 1.00 68.09  ? 519 ILE   A CB  1 
ATOM   4008 C CG1 . ILE   A 1 493 ? 159.705 154.260 175.145 1.00 70.85  ? 519 ILE   A CG1 1 
ATOM   4009 C CG2 . ILE   A 1 493 ? 161.332 155.231 173.486 1.00 72.91  ? 519 ILE   A CG2 1 
ATOM   4010 C CD1 . ILE   A 1 493 ? 160.268 152.862 175.303 1.00 76.11  ? 519 ILE   A CD1 1 
ATOM   4011 N N   . LYS   A 1 494 ? 158.555 156.493 171.204 1.00 78.16  ? 520 LYS   A N   1 
ATOM   4012 C CA  . LYS   A 1 494 ? 158.760 157.193 169.944 1.00 79.04  ? 520 LYS   A CA  1 
ATOM   4013 C C   . LYS   A 1 494 ? 158.296 158.643 170.009 1.00 80.60  ? 520 LYS   A C   1 
ATOM   4014 O O   . LYS   A 1 494 ? 158.783 159.468 169.228 1.00 83.52  ? 520 LYS   A O   1 
ATOM   4015 C CB  . LYS   A 1 494 ? 158.035 156.456 168.814 1.00 80.92  ? 520 LYS   A CB  1 
ATOM   4016 C CG  . LYS   A 1 494 ? 158.323 156.966 167.394 1.00 84.26  ? 520 LYS   A CG  1 
ATOM   4017 C CD  . LYS   A 1 494 ? 159.783 156.801 166.953 1.00 86.75  ? 520 LYS   A CD  1 
ATOM   4018 C CE  . LYS   A 1 494 ? 160.230 155.343 166.881 1.00 87.17  ? 520 LYS   A CE  1 
ATOM   4019 N NZ  . LYS   A 1 494 ? 159.366 154.505 166.004 1.00 92.01  ? 520 LYS   A NZ  1 
ATOM   4020 N N   . SER   A 1 495 ? 157.378 158.977 170.918 1.00 77.00  ? 521 SER   A N   1 
ATOM   4021 C CA  . SER   A 1 495 ? 156.790 160.311 170.965 1.00 74.73  ? 521 SER   A CA  1 
ATOM   4022 C C   . SER   A 1 495 ? 157.485 161.249 171.944 1.00 75.15  ? 521 SER   A C   1 
ATOM   4023 O O   . SER   A 1 495 ? 157.115 162.426 172.008 1.00 81.27  ? 521 SER   A O   1 
ATOM   4024 C CB  . SER   A 1 495 ? 155.305 160.217 171.327 1.00 83.64  ? 521 SER   A CB  1 
ATOM   4025 O OG  . SER   A 1 495 ? 155.123 159.636 172.606 1.00 91.12  ? 521 SER   A OG  1 
ATOM   4026 N N   . SER   A 1 496 ? 158.475 160.773 172.698 1.00 71.87  ? 522 SER   A N   1 
ATOM   4027 C CA  . SER   A 1 496 ? 159.159 161.571 173.707 1.00 73.44  ? 522 SER   A CA  1 
ATOM   4028 C C   . SER   A 1 496 ? 160.530 162.058 173.254 1.00 78.12  ? 522 SER   A C   1 
ATOM   4029 O O   . SER   A 1 496 ? 161.265 162.631 174.064 1.00 84.39  ? 522 SER   A O   1 
ATOM   4030 C CB  . SER   A 1 496 ? 159.298 160.765 174.999 1.00 81.15  ? 522 SER   A CB  1 
ATOM   4031 O OG  . SER   A 1 496 ? 159.923 161.528 176.018 1.00 90.26  ? 522 SER   A OG  1 
ATOM   4032 N N   . LEU   A 1 497 ? 160.887 161.854 171.990 1.00 82.19  ? 523 LEU   A N   1 
ATOM   4033 C CA  . LEU   A 1 497 ? 162.203 162.195 171.472 1.00 84.89  ? 523 LEU   A CA  1 
ATOM   4034 C C   . LEU   A 1 497 ? 162.150 163.516 170.711 1.00 89.12  ? 523 LEU   A C   1 
ATOM   4035 O O   . LEU   A 1 497 ? 161.088 163.978 170.289 1.00 93.07  ? 523 LEU   A O   1 
ATOM   4036 C CB  . LEU   A 1 497 ? 162.725 161.083 170.558 1.00 83.51  ? 523 LEU   A CB  1 
ATOM   4037 C CG  . LEU   A 1 497 ? 162.763 159.674 171.157 1.00 81.11  ? 523 LEU   A CG  1 
ATOM   4038 C CD1 . LEU   A 1 497 ? 163.216 158.668 170.115 1.00 79.07  ? 523 LEU   A CD1 1 
ATOM   4039 C CD2 . LEU   A 1 497 ? 163.667 159.619 172.376 1.00 79.87  ? 523 LEU   A CD2 1 
ATOM   4040 N N   . ASP   A 1 498 ? 163.324 164.117 170.539 1.00 91.26  ? 524 ASP   A N   1 
ATOM   4041 C CA  . ASP   A 1 498 ? 163.439 165.416 169.891 1.00 92.41  ? 524 ASP   A CA  1 
ATOM   4042 C C   . ASP   A 1 498 ? 163.485 165.227 168.375 1.00 92.63  ? 524 ASP   A C   1 
ATOM   4043 O O   . ASP   A 1 498 ? 163.266 164.131 167.852 1.00 91.03  ? 524 ASP   A O   1 
ATOM   4044 C CB  . ASP   A 1 498 ? 164.668 166.154 170.415 1.00 94.04  ? 524 ASP   A CB  1 
ATOM   4045 C CG  . ASP   A 1 498 ? 164.657 166.303 171.923 1.00 103.93 ? 524 ASP   A CG  1 
ATOM   4046 O OD1 . ASP   A 1 498 ? 163.701 165.818 172.563 1.00 102.49 ? 524 ASP   A OD1 1 
ATOM   4047 O OD2 . ASP   A 1 498 ? 165.605 166.906 172.469 1.00 108.26 ? 524 ASP   A OD2 1 
ATOM   4048 N N   . ASN   A 1 499 ? 163.771 166.306 167.648 1.00 94.92  ? 525 ASN   A N   1 
ATOM   4049 C CA  . ASN   A 1 499 ? 163.798 166.266 166.192 1.00 93.98  ? 525 ASN   A CA  1 
ATOM   4050 C C   . ASN   A 1 499 ? 165.057 165.618 165.629 1.00 94.48  ? 525 ASN   A C   1 
ATOM   4051 O O   . ASN   A 1 499 ? 165.094 165.336 164.426 1.00 98.94  ? 525 ASN   A O   1 
ATOM   4052 C CB  . ASN   A 1 499 ? 163.670 167.683 165.629 1.00 98.60  ? 525 ASN   A CB  1 
ATOM   4053 C CG  . ASN   A 1 499 ? 162.504 168.444 166.223 1.00 99.74  ? 525 ASN   A CG  1 
ATOM   4054 O OD1 . ASN   A 1 499 ? 162.067 168.161 167.338 1.00 96.84  ? 525 ASN   A OD1 1 
ATOM   4055 N ND2 . ASN   A 1 499 ? 161.994 169.418 165.480 1.00 101.04 ? 525 ASN   A ND2 1 
ATOM   4056 N N   . HIS   A 1 500 ? 166.077 165.376 166.453 1.00 92.43  ? 526 HIS   A N   1 
ATOM   4057 C CA  . HIS   A 1 500 ? 167.337 164.782 166.019 1.00 91.34  ? 526 HIS   A CA  1 
ATOM   4058 C C   . HIS   A 1 500 ? 167.519 163.351 166.496 1.00 89.24  ? 526 HIS   A C   1 
ATOM   4059 O O   . HIS   A 1 500 ? 168.039 162.520 165.749 1.00 89.20  ? 526 HIS   A O   1 
ATOM   4060 C CB  . HIS   A 1 500 ? 168.515 165.623 166.521 1.00 94.63  ? 526 HIS   A CB  1 
ATOM   4061 C CG  . HIS   A 1 500 ? 168.258 167.098 166.495 1.00 103.95 ? 526 HIS   A CG  1 
ATOM   4062 N ND1 . HIS   A 1 500 ? 168.124 167.810 165.323 1.00 110.80 ? 526 HIS   A ND1 1 
ATOM   4063 C CD2 . HIS   A 1 500 ? 168.117 167.995 167.499 1.00 105.78 ? 526 HIS   A CD2 1 
ATOM   4064 C CE1 . HIS   A 1 500 ? 167.908 169.082 165.606 1.00 110.19 ? 526 HIS   A CE1 1 
ATOM   4065 N NE2 . HIS   A 1 500 ? 167.899 169.221 166.920 1.00 113.46 ? 526 HIS   A NE2 1 
ATOM   4066 N N   . THR   A 1 501 ? 167.110 163.048 167.726 1.00 79.86  ? 527 THR   A N   1 
ATOM   4067 C CA  . THR   A 1 501 ? 167.264 161.703 168.261 1.00 66.58  ? 527 THR   A CA  1 
ATOM   4068 C C   . THR   A 1 501 ? 166.437 160.708 167.457 1.00 62.80  ? 527 THR   A C   1 
ATOM   4069 O O   . THR   A 1 501 ? 165.348 161.026 166.972 1.00 67.08  ? 527 THR   A O   1 
ATOM   4070 C CB  . THR   A 1 501 ? 166.842 161.673 169.731 1.00 71.47  ? 527 THR   A CB  1 
ATOM   4071 O OG1 . THR   A 1 501 ? 167.535 162.699 170.452 1.00 76.78  ? 527 THR   A OG1 1 
ATOM   4072 C CG2 . THR   A 1 501 ? 167.156 160.322 170.358 1.00 74.23  ? 527 THR   A CG2 1 
ATOM   4073 N N   . GLU   A 1 502 ? 166.973 159.499 167.311 1.00 65.50  ? 528 GLU   A N   1 
ATOM   4074 C CA  . GLU   A 1 502 ? 166.306 158.402 166.630 1.00 67.93  ? 528 GLU   A CA  1 
ATOM   4075 C C   . GLU   A 1 502 ? 166.515 157.130 167.438 1.00 64.92  ? 528 GLU   A C   1 
ATOM   4076 O O   . GLU   A 1 502 ? 167.525 156.979 168.136 1.00 70.65  ? 528 GLU   A O   1 
ATOM   4077 C CB  . GLU   A 1 502 ? 166.831 158.219 165.202 1.00 76.86  ? 528 GLU   A CB  1 
ATOM   4078 C CG  . GLU   A 1 502 ? 166.577 159.410 164.292 1.00 85.04  ? 528 GLU   A CG  1 
ATOM   4079 C CD  . GLU   A 1 502 ? 167.098 159.191 162.886 1.00 96.45  ? 528 GLU   A CD  1 
ATOM   4080 O OE1 . GLU   A 1 502 ? 167.644 158.100 162.615 1.00 92.84  ? 528 GLU   A OE1 1 
ATOM   4081 O OE2 . GLU   A 1 502 ? 166.962 160.109 162.050 1.00 101.01 ? 528 GLU   A OE2 1 
ATOM   4082 N N   . VAL   A 1 503 ? 165.551 156.214 167.329 1.00 53.41  ? 529 VAL   A N   1 
ATOM   4083 C CA  . VAL   A 1 503 ? 165.496 155.010 168.150 1.00 51.89  ? 529 VAL   A CA  1 
ATOM   4084 C C   . VAL   A 1 503 ? 165.239 153.805 167.256 1.00 57.80  ? 529 VAL   A C   1 
ATOM   4085 O O   . VAL   A 1 503 ? 164.406 153.862 166.345 1.00 66.70  ? 529 VAL   A O   1 
ATOM   4086 C CB  . VAL   A 1 503 ? 164.414 155.116 169.246 1.00 59.49  ? 529 VAL   A CB  1 
ATOM   4087 C CG1 . VAL   A 1 503 ? 163.014 155.231 168.640 1.00 67.35  ? 529 VAL   A CG1 1 
ATOM   4088 C CG2 . VAL   A 1 503 ? 164.493 153.930 170.191 1.00 60.84  ? 529 VAL   A CG2 1 
ATOM   4089 N N   . VAL   A 1 504 ? 165.963 152.717 167.519 1.00 56.44  ? 530 VAL   A N   1 
ATOM   4090 C CA  . VAL   A 1 504 ? 165.810 151.453 166.803 1.00 52.87  ? 530 VAL   A CA  1 
ATOM   4091 C C   . VAL   A 1 504 ? 165.656 150.346 167.836 1.00 56.89  ? 530 VAL   A C   1 
ATOM   4092 O O   . VAL   A 1 504 ? 166.531 150.167 168.690 1.00 61.82  ? 530 VAL   A O   1 
ATOM   4093 C CB  . VAL   A 1 504 ? 167.003 151.165 165.877 1.00 49.28  ? 530 VAL   A CB  1 
ATOM   4094 C CG1 . VAL   A 1 504 ? 166.879 149.780 165.270 1.00 54.00  ? 530 VAL   A CG1 1 
ATOM   4095 C CG2 . VAL   A 1 504 ? 167.098 152.216 164.784 1.00 54.55  ? 530 VAL   A CG2 1 
ATOM   4096 N N   . PHE   A 1 505 ? 164.558 149.600 167.753 1.00 54.00  ? 531 PHE   A N   1 
ATOM   4097 C CA  . PHE   A 1 505 ? 164.262 148.524 168.690 1.00 52.48  ? 531 PHE   A CA  1 
ATOM   4098 C C   . PHE   A 1 505 ? 164.694 147.189 168.101 1.00 54.27  ? 531 PHE   A C   1 
ATOM   4099 O O   . PHE   A 1 505 ? 164.462 146.921 166.918 1.00 62.04  ? 531 PHE   A O   1 
ATOM   4100 C CB  . PHE   A 1 505 ? 162.771 148.483 169.020 1.00 59.34  ? 531 PHE   A CB  1 
ATOM   4101 C CG  . PHE   A 1 505 ? 162.234 149.774 169.561 1.00 65.74  ? 531 PHE   A CG  1 
ATOM   4102 C CD1 . PHE   A 1 505 ? 162.609 150.224 170.812 1.00 64.29  ? 531 PHE   A CD1 1 
ATOM   4103 C CD2 . PHE   A 1 505 ? 161.347 150.533 168.822 1.00 68.59  ? 531 PHE   A CD2 1 
ATOM   4104 C CE1 . PHE   A 1 505 ? 162.117 151.410 171.310 1.00 67.84  ? 531 PHE   A CE1 1 
ATOM   4105 C CE2 . PHE   A 1 505 ? 160.851 151.719 169.318 1.00 67.25  ? 531 PHE   A CE2 1 
ATOM   4106 C CZ  . PHE   A 1 505 ? 161.235 152.156 170.563 1.00 69.91  ? 531 PHE   A CZ  1 
ATOM   4107 N N   . ILE   A 1 506 ? 165.323 146.354 168.928 1.00 49.77  ? 532 ILE   A N   1 
ATOM   4108 C CA  . ILE   A 1 506 ? 165.836 145.056 168.510 1.00 50.45  ? 532 ILE   A CA  1 
ATOM   4109 C C   . ILE   A 1 506 ? 165.369 144.004 169.505 1.00 59.23  ? 532 ILE   A C   1 
ATOM   4110 O O   . ILE   A 1 506 ? 165.351 144.245 170.718 1.00 65.94  ? 532 ILE   A O   1 
ATOM   4111 C CB  . ILE   A 1 506 ? 167.377 145.059 168.412 1.00 55.67  ? 532 ILE   A CB  1 
ATOM   4112 C CG1 . ILE   A 1 506 ? 167.869 146.041 167.338 1.00 58.79  ? 532 ILE   A CG1 1 
ATOM   4113 C CG2 . ILE   A 1 506 ? 167.906 143.652 168.166 1.00 58.68  ? 532 ILE   A CG2 1 
ATOM   4114 C CD1 . ILE   A 1 506 ? 167.442 145.723 165.911 1.00 59.01  ? 532 ILE   A CD1 1 
ATOM   4115 N N   . ALA   A 1 507 ? 164.967 142.846 168.982 1.00 65.33  ? 533 ALA   A N   1 
ATOM   4116 C CA  . ALA   A 1 507 ? 164.641 141.668 169.777 1.00 58.50  ? 533 ALA   A CA  1 
ATOM   4117 C C   . ALA   A 1 507 ? 165.453 140.504 169.236 1.00 55.65  ? 533 ALA   A C   1 
ATOM   4118 O O   . ALA   A 1 507 ? 165.358 140.182 168.047 1.00 61.14  ? 533 ALA   A O   1 
ATOM   4119 C CB  . ALA   A 1 507 ? 163.146 141.352 169.727 1.00 59.38  ? 533 ALA   A CB  1 
ATOM   4120 N N   . ASP   A 1 508 ? 166.236 139.873 170.106 1.00 57.95  ? 534 ASP   A N   1 
ATOM   4121 C CA  . ASP   A 1 508 ? 167.248 138.908 169.711 1.00 62.79  ? 534 ASP   A CA  1 
ATOM   4122 C C   . ASP   A 1 508 ? 167.029 137.585 170.432 1.00 67.56  ? 534 ASP   A C   1 
ATOM   4123 O O   . ASP   A 1 508 ? 166.579 137.546 171.584 1.00 72.69  ? 534 ASP   A O   1 
ATOM   4124 C CB  . ASP   A 1 508 ? 168.653 139.444 170.014 1.00 64.23  ? 534 ASP   A CB  1 
ATOM   4125 C CG  . ASP   A 1 508 ? 169.747 138.621 169.370 1.00 67.78  ? 534 ASP   A CG  1 
ATOM   4126 O OD1 . ASP   A 1 508 ? 169.430 137.642 168.664 1.00 68.12  ? 534 ASP   A OD1 1 
ATOM   4127 O OD2 . ASP   A 1 508 ? 170.932 138.957 169.572 1.00 70.25  ? 534 ASP   A OD2 1 
ATOM   4128 N N   . PHE   A 1 509 ? 167.361 136.506 169.730 1.00 65.47  ? 535 PHE   A N   1 
ATOM   4129 C CA  . PHE   A 1 509 ? 167.189 135.149 170.215 1.00 63.80  ? 535 PHE   A CA  1 
ATOM   4130 C C   . PHE   A 1 509 ? 168.333 134.758 171.148 1.00 65.97  ? 535 PHE   A C   1 
ATOM   4131 O O   . PHE   A 1 509 ? 169.398 135.379 171.131 1.00 71.44  ? 535 PHE   A O   1 
ATOM   4132 C CB  . PHE   A 1 509 ? 167.125 134.189 169.032 1.00 65.79  ? 535 PHE   A CB  1 
ATOM   4133 C CG  . PHE   A 1 509 ? 165.883 134.331 168.205 1.00 62.38  ? 535 PHE   A CG  1 
ATOM   4134 C CD1 . PHE   A 1 509 ? 165.791 135.306 167.230 1.00 62.75  ? 535 PHE   A CD1 1 
ATOM   4135 C CD2 . PHE   A 1 509 ? 164.809 133.486 168.398 1.00 64.78  ? 535 PHE   A CD2 1 
ATOM   4136 C CE1 . PHE   A 1 509 ? 164.653 135.437 166.470 1.00 60.14  ? 535 PHE   A CE1 1 
ATOM   4137 C CE2 . PHE   A 1 509 ? 163.668 133.614 167.639 1.00 67.31  ? 535 PHE   A CE2 1 
ATOM   4138 C CZ  . PHE   A 1 509 ? 163.591 134.591 166.675 1.00 62.87  ? 535 PHE   A CZ  1 
ATOM   4139 N N   . PRO   A 1 510 ? 168.145 133.728 171.975 1.00 65.16  ? 536 PRO   A N   1 
ATOM   4140 C CA  . PRO   A 1 510 ? 169.235 133.303 172.859 1.00 65.30  ? 536 PRO   A CA  1 
ATOM   4141 C C   . PRO   A 1 510 ? 170.366 132.644 172.089 1.00 71.44  ? 536 PRO   A C   1 
ATOM   4142 O O   . PRO   A 1 510 ? 170.141 131.844 171.177 1.00 76.10  ? 536 PRO   A O   1 
ATOM   4143 C CB  . PRO   A 1 510 ? 168.554 132.313 173.807 1.00 67.44  ? 536 PRO   A CB  1 
ATOM   4144 C CG  . PRO   A 1 510 ? 167.422 131.782 173.030 1.00 68.03  ? 536 PRO   A CG  1 
ATOM   4145 C CD  . PRO   A 1 510 ? 166.922 132.943 172.227 1.00 67.27  ? 536 PRO   A CD  1 
ATOM   4146 N N   . GLY   A 1 511 ? 171.591 132.989 172.467 1.00 71.83  ? 537 GLY   A N   1 
ATOM   4147 C CA  . GLY   A 1 511 ? 172.796 132.420 171.887 1.00 70.72  ? 537 GLY   A CA  1 
ATOM   4148 C C   . GLY   A 1 511 ? 173.350 133.215 170.727 1.00 71.69  ? 537 GLY   A C   1 
ATOM   4149 O O   . GLY   A 1 511 ? 174.566 133.364 170.598 1.00 77.87  ? 537 GLY   A O   1 
ATOM   4150 N N   . LEU   A 1 512 ? 172.473 133.731 169.874 1.00 68.51  ? 538 LEU   A N   1 
ATOM   4151 C CA  . LEU   A 1 512 ? 172.914 134.545 168.754 1.00 69.95  ? 538 LEU   A CA  1 
ATOM   4152 C C   . LEU   A 1 512 ? 173.420 135.892 169.252 1.00 72.40  ? 538 LEU   A C   1 
ATOM   4153 O O   . LEU   A 1 512 ? 173.005 136.385 170.304 1.00 76.09  ? 538 LEU   A O   1 
ATOM   4154 C CB  . LEU   A 1 512 ? 171.774 134.747 167.755 1.00 71.15  ? 538 LEU   A CB  1 
ATOM   4155 C CG  . LEU   A 1 512 ? 171.476 133.598 166.786 1.00 71.18  ? 538 LEU   A CG  1 
ATOM   4156 C CD1 . LEU   A 1 512 ? 171.055 132.330 167.510 1.00 73.61  ? 538 LEU   A CD1 1 
ATOM   4157 C CD2 . LEU   A 1 512 ? 170.406 134.024 165.800 1.00 71.30  ? 538 LEU   A CD2 1 
ATOM   4158 N N   . HIS   A 1 513 ? 174.333 136.483 168.483 1.00 70.21  ? 539 HIS   A N   1 
ATOM   4159 C CA  . HIS   A 1 513 ? 174.942 137.760 168.822 1.00 64.99  ? 539 HIS   A CA  1 
ATOM   4160 C C   . HIS   A 1 513 ? 174.933 138.670 167.606 1.00 61.95  ? 539 HIS   A C   1 
ATOM   4161 O O   . HIS   A 1 513 ? 175.026 138.209 166.466 1.00 62.77  ? 539 HIS   A O   1 
ATOM   4162 C CB  . HIS   A 1 513 ? 176.374 137.574 169.322 1.00 64.00  ? 539 HIS   A CB  1 
ATOM   4163 C CG  . HIS   A 1 513 ? 177.333 137.130 168.264 1.00 61.05  ? 539 HIS   A CG  1 
ATOM   4164 N ND1 . HIS   A 1 513 ? 177.966 138.011 167.414 1.00 59.34  ? 539 HIS   A ND1 1 
ATOM   4165 C CD2 . HIS   A 1 513 ? 177.773 135.897 167.922 1.00 68.88  ? 539 HIS   A CD2 1 
ATOM   4166 C CE1 . HIS   A 1 513 ? 178.753 137.340 166.593 1.00 71.03  ? 539 HIS   A CE1 1 
ATOM   4167 N NE2 . HIS   A 1 513 ? 178.653 136.055 166.879 1.00 74.72  ? 539 HIS   A NE2 1 
ATOM   4168 N N   . LEU   A 1 514 ? 174.829 139.971 167.866 1.00 63.28  ? 540 LEU   A N   1 
ATOM   4169 C CA  . LEU   A 1 514 ? 174.771 140.992 166.826 1.00 59.08  ? 540 LEU   A CA  1 
ATOM   4170 C C   . LEU   A 1 514 ? 176.031 141.843 166.895 1.00 60.30  ? 540 LEU   A C   1 
ATOM   4171 O O   . LEU   A 1 514 ? 176.344 142.406 167.949 1.00 64.10  ? 540 LEU   A O   1 
ATOM   4172 C CB  . LEU   A 1 514 ? 173.515 141.852 166.980 1.00 53.85  ? 540 LEU   A CB  1 
ATOM   4173 C CG  . LEU   A 1 514 ? 173.431 143.200 166.261 1.00 53.91  ? 540 LEU   A CG  1 
ATOM   4174 C CD1 . LEU   A 1 514 ? 173.525 143.022 164.755 1.00 60.51  ? 540 LEU   A CD1 1 
ATOM   4175 C CD2 . LEU   A 1 514 ? 172.144 143.900 166.631 1.00 56.62  ? 540 LEU   A CD2 1 
ATOM   4176 N N   . GLU   A 1 515 ? 176.736 141.938 165.770 1.00 60.56  ? 541 GLU   A N   1 
ATOM   4177 C CA  . GLU   A 1 515 ? 177.948 142.736 165.636 1.00 55.79  ? 541 GLU   A CA  1 
ATOM   4178 C C   . GLU   A 1 515 ? 177.623 143.993 164.845 1.00 59.05  ? 541 GLU   A C   1 
ATOM   4179 O O   . GLU   A 1 515 ? 177.084 143.907 163.737 1.00 71.68  ? 541 GLU   A O   1 
ATOM   4180 C CB  . GLU   A 1 515 ? 179.043 141.934 164.933 1.00 60.33  ? 541 GLU   A CB  1 
ATOM   4181 C CG  . GLU   A 1 515 ? 180.350 142.679 164.726 1.00 65.48  ? 541 GLU   A CG  1 
ATOM   4182 C CD  . GLU   A 1 515 ? 181.428 141.797 164.136 1.00 75.45  ? 541 GLU   A CD  1 
ATOM   4183 O OE1 . GLU   A 1 515 ? 181.142 140.616 163.850 1.00 75.53  ? 541 GLU   A OE1 1 
ATOM   4184 O OE2 . GLU   A 1 515 ? 182.562 142.285 163.956 1.00 80.22  ? 541 GLU   A OE2 1 
ATOM   4185 N N   . ASN   A 1 516 ? 177.952 145.155 165.410 1.00 56.49  ? 542 ASN   A N   1 
ATOM   4186 C CA  . ASN   A 1 516 ? 177.585 146.437 164.831 1.00 54.06  ? 542 ASN   A CA  1 
ATOM   4187 C C   . ASN   A 1 516 ? 178.781 147.377 164.862 1.00 55.78  ? 542 ASN   A C   1 
ATOM   4188 O O   . ASN   A 1 516 ? 179.666 147.253 165.713 1.00 60.81  ? 542 ASN   A O   1 
ATOM   4189 C CB  . ASN   A 1 516 ? 176.400 147.050 165.585 1.00 54.97  ? 542 ASN   A CB  1 
ATOM   4190 C CG  . ASN   A 1 516 ? 175.932 148.351 164.981 1.00 68.68  ? 542 ASN   A CG  1 
ATOM   4191 O OD1 . ASN   A 1 516 ? 176.078 148.579 163.780 1.00 78.41  ? 542 ASN   A OD1 1 
ATOM   4192 N ND2 . ASN   A 1 516 ? 175.374 149.221 165.811 1.00 71.55  ? 542 ASN   A ND2 1 
ATOM   4193 N N   . PHE   A 1 517 ? 178.808 148.304 163.904 1.00 61.99  ? 543 PHE   A N   1 
ATOM   4194 C CA  . PHE   A 1 517 ? 179.851 149.320 163.792 1.00 61.58  ? 543 PHE   A CA  1 
ATOM   4195 C C   . PHE   A 1 517 ? 179.190 150.689 163.784 1.00 63.72  ? 543 PHE   A C   1 
ATOM   4196 O O   . PHE   A 1 517 ? 178.531 151.057 162.806 1.00 65.86  ? 543 PHE   A O   1 
ATOM   4197 C CB  . PHE   A 1 517 ? 180.686 149.123 162.530 1.00 55.73  ? 543 PHE   A CB  1 
ATOM   4198 C CG  . PHE   A 1 517 ? 181.674 150.221 162.288 1.00 51.50  ? 543 PHE   A CG  1 
ATOM   4199 C CD1 . PHE   A 1 517 ? 182.806 150.337 163.072 1.00 58.57  ? 543 PHE   A CD1 1 
ATOM   4200 C CD2 . PHE   A 1 517 ? 181.473 151.135 161.274 1.00 55.23  ? 543 PHE   A CD2 1 
ATOM   4201 C CE1 . PHE   A 1 517 ? 183.716 151.347 162.850 1.00 60.58  ? 543 PHE   A CE1 1 
ATOM   4202 C CE2 . PHE   A 1 517 ? 182.379 152.144 161.048 1.00 63.54  ? 543 PHE   A CE2 1 
ATOM   4203 C CZ  . PHE   A 1 517 ? 183.501 152.252 161.839 1.00 62.07  ? 543 PHE   A CZ  1 
ATOM   4204 N N   . VAL   A 1 518 ? 179.368 151.443 164.866 1.00 62.51  ? 544 VAL   A N   1 
ATOM   4205 C CA  . VAL   A 1 518 ? 178.834 152.797 164.928 1.00 63.02  ? 544 VAL   A CA  1 
ATOM   4206 C C   . VAL   A 1 518 ? 179.700 153.707 164.067 1.00 69.13  ? 544 VAL   A C   1 
ATOM   4207 O O   . VAL   A 1 518 ? 180.928 153.748 164.219 1.00 74.19  ? 544 VAL   A O   1 
ATOM   4208 C CB  . VAL   A 1 518 ? 178.777 153.288 166.383 1.00 64.16  ? 544 VAL   A CB  1 
ATOM   4209 C CG1 . VAL   A 1 518 ? 178.048 154.628 166.471 1.00 66.47  ? 544 VAL   A CG1 1 
ATOM   4210 C CG2 . VAL   A 1 518 ? 178.110 152.247 167.275 1.00 61.92  ? 544 VAL   A CG2 1 
ATOM   4211 N N   . SER   A 1 519 ? 179.065 154.438 163.156 1.00 64.42  ? 545 SER   A N   1 
ATOM   4212 C CA  . SER   A 1 519 ? 179.807 155.302 162.253 1.00 63.07  ? 545 SER   A CA  1 
ATOM   4213 C C   . SER   A 1 519 ? 180.423 156.474 163.013 1.00 69.62  ? 545 SER   A C   1 
ATOM   4214 O O   . SER   A 1 519 ? 179.988 156.839 164.109 1.00 75.78  ? 545 SER   A O   1 
ATOM   4215 C CB  . SER   A 1 519 ? 178.899 155.819 161.138 1.00 67.72  ? 545 SER   A CB  1 
ATOM   4216 O OG  . SER   A 1 519 ? 177.789 156.517 161.670 1.00 73.86  ? 545 SER   A OG  1 
ATOM   4217 N N   . GLU   A 1 520 ? 181.459 157.063 162.413 1.00 74.89  ? 546 GLU   A N   1 
ATOM   4218 C CA  . GLU   A 1 520 ? 182.161 158.166 163.060 1.00 77.58  ? 546 GLU   A CA  1 
ATOM   4219 C C   . GLU   A 1 520 ? 181.270 159.391 163.216 1.00 68.96  ? 546 GLU   A C   1 
ATOM   4220 O O   . GLU   A 1 520 ? 181.451 160.170 164.158 1.00 66.87  ? 546 GLU   A O   1 
ATOM   4221 C CB  . GLU   A 1 520 ? 183.417 158.528 162.266 1.00 81.18  ? 546 GLU   A CB  1 
ATOM   4222 C CG  . GLU   A 1 520 ? 184.430 157.400 162.164 1.00 84.50  ? 546 GLU   A CG  1 
ATOM   4223 C CD  . GLU   A 1 520 ? 185.669 157.800 161.390 1.00 91.28  ? 546 GLU   A CD  1 
ATOM   4224 O OE1 . GLU   A 1 520 ? 185.743 158.965 160.946 1.00 92.52  ? 546 GLU   A OE1 1 
ATOM   4225 O OE2 . GLU   A 1 520 ? 186.570 156.951 161.226 1.00 94.36  ? 546 GLU   A OE2 1 
ATOM   4226 N N   . ASP   A 1 521 ? 180.321 159.589 162.301 1.00 67.52  ? 547 ASP   A N   1 
ATOM   4227 C CA  . ASP   A 1 521 ? 179.435 160.742 162.400 1.00 76.03  ? 547 ASP   A CA  1 
ATOM   4228 C C   . ASP   A 1 521 ? 178.521 160.639 163.615 1.00 80.54  ? 547 ASP   A C   1 
ATOM   4229 O O   . ASP   A 1 521 ? 178.282 161.637 164.304 1.00 82.62  ? 547 ASP   A O   1 
ATOM   4230 C CB  . ASP   A 1 521 ? 178.611 160.874 161.121 1.00 81.31  ? 547 ASP   A CB  1 
ATOM   4231 C CG  . ASP   A 1 521 ? 179.475 161.018 159.884 1.00 90.55  ? 547 ASP   A CG  1 
ATOM   4232 O OD1 . ASP   A 1 521 ? 180.581 161.587 159.992 1.00 90.25  ? 547 ASP   A OD1 1 
ATOM   4233 O OD2 . ASP   A 1 521 ? 179.049 160.559 158.803 1.00 94.62  ? 547 ASP   A OD2 1 
ATOM   4234 N N   . LEU   A 1 522 ? 178.002 159.443 163.897 1.00 75.83  ? 548 LEU   A N   1 
ATOM   4235 C CA  . LEU   A 1 522 ? 176.990 159.259 164.938 1.00 63.26  ? 548 LEU   A CA  1 
ATOM   4236 C C   . LEU   A 1 522 ? 177.666 159.196 166.304 1.00 64.42  ? 548 LEU   A C   1 
ATOM   4237 O O   . LEU   A 1 522 ? 177.935 158.129 166.860 1.00 67.55  ? 548 LEU   A O   1 
ATOM   4238 C CB  . LEU   A 1 522 ? 176.166 158.006 164.672 1.00 58.53  ? 548 LEU   A CB  1 
ATOM   4239 C CG  . LEU   A 1 522 ? 174.929 158.185 163.793 1.00 65.28  ? 548 LEU   A CG  1 
ATOM   4240 C CD1 . LEU   A 1 522 ? 175.284 158.778 162.437 1.00 75.83  ? 548 LEU   A CD1 1 
ATOM   4241 C CD2 . LEU   A 1 522 ? 174.217 156.855 163.625 1.00 65.71  ? 548 LEU   A CD2 1 
ATOM   4242 N N   . GLY   A 1 523 ? 177.952 160.377 166.846 1.00 63.05  ? 549 GLY   A N   1 
ATOM   4243 C CA  . GLY   A 1 523 ? 178.303 160.483 168.243 1.00 61.87  ? 549 GLY   A CA  1 
ATOM   4244 C C   . GLY   A 1 523 ? 177.076 160.456 169.137 1.00 68.70  ? 549 GLY   A C   1 
ATOM   4245 O O   . GLY   A 1 523 ? 175.944 160.622 168.685 1.00 73.01  ? 549 GLY   A O   1 
ATOM   4246 N N   . ASN   A 1 524 ? 177.312 160.248 170.432 1.00 66.38  ? 550 ASN   A N   1 
ATOM   4247 C CA  . ASN   A 1 524 ? 176.248 160.236 171.436 1.00 62.57  ? 550 ASN   A CA  1 
ATOM   4248 C C   . ASN   A 1 524 ? 175.225 159.138 171.132 1.00 63.19  ? 550 ASN   A C   1 
ATOM   4249 O O   . ASN   A 1 524 ? 174.038 159.393 170.919 1.00 63.03  ? 550 ASN   A O   1 
ATOM   4250 C CB  . ASN   A 1 524 ? 175.576 161.612 171.525 1.00 66.80  ? 550 ASN   A CB  1 
ATOM   4251 C CG  . ASN   A 1 524 ? 174.567 161.704 172.658 1.00 77.73  ? 550 ASN   A CG  1 
ATOM   4252 O OD1 . ASN   A 1 524 ? 174.928 161.595 173.829 1.00 83.83  ? 550 ASN   A OD1 1 
ATOM   4253 N ND2 . ASN   A 1 524 ? 173.301 161.921 172.317 1.00 82.79  ? 550 ASN   A ND2 1 
ATOM   4254 N N   . THR   A 1 525 ? 175.719 157.901 171.110 1.00 60.64  ? 551 THR   A N   1 
ATOM   4255 C CA  . THR   A 1 525 ? 174.911 156.709 170.884 1.00 53.71  ? 551 THR   A CA  1 
ATOM   4256 C C   . THR   A 1 525 ? 174.836 155.910 172.177 1.00 60.74  ? 551 THR   A C   1 
ATOM   4257 O O   . THR   A 1 525 ? 175.861 155.697 172.835 1.00 65.18  ? 551 THR   A O   1 
ATOM   4258 C CB  . THR   A 1 525 ? 175.504 155.847 169.768 1.00 53.86  ? 551 THR   A CB  1 
ATOM   4259 O OG1 . THR   A 1 525 ? 175.630 156.625 168.572 1.00 61.10  ? 551 THR   A OG1 1 
ATOM   4260 C CG2 . THR   A 1 525 ? 174.623 154.641 169.492 1.00 56.01  ? 551 THR   A CG2 1 
ATOM   4261 N N   . SER   A 1 526 ? 173.628 155.473 172.539 1.00 65.62  ? 552 SER   A N   1 
ATOM   4262 C CA  . SER   A 1 526 ? 173.386 154.765 173.789 1.00 58.01  ? 552 SER   A CA  1 
ATOM   4263 C C   . SER   A 1 526 ? 172.583 153.499 173.534 1.00 58.60  ? 552 SER   A C   1 
ATOM   4264 O O   . SER   A 1 526 ? 171.758 153.442 172.619 1.00 65.15  ? 552 SER   A O   1 
ATOM   4265 C CB  . SER   A 1 526 ? 172.634 155.640 174.795 1.00 63.03  ? 552 SER   A CB  1 
ATOM   4266 O OG  . SER   A 1 526 ? 171.364 156.012 174.290 1.00 68.79  ? 552 SER   A OG  1 
ATOM   4267 N N   . ILE   A 1 527 ? 172.835 152.487 174.365 1.00 59.40  ? 553 ILE   A N   1 
ATOM   4268 C CA  . ILE   A 1 527 ? 172.137 151.205 174.312 1.00 60.22  ? 553 ILE   A CA  1 
ATOM   4269 C C   . ILE   A 1 527 ? 171.478 150.964 175.662 1.00 63.12  ? 553 ILE   A C   1 
ATOM   4270 O O   . ILE   A 1 527 ? 172.122 151.109 176.709 1.00 70.97  ? 553 ILE   A O   1 
ATOM   4271 C CB  . ILE   A 1 527 ? 173.079 150.043 173.940 1.00 53.93  ? 553 ILE   A CB  1 
ATOM   4272 C CG1 . ILE   A 1 527 ? 172.293 148.733 173.837 1.00 49.46  ? 553 ILE   A CG1 1 
ATOM   4273 C CG2 . ILE   A 1 527 ? 174.216 149.894 174.944 1.00 60.09  ? 553 ILE   A CG2 1 
ATOM   4274 C CD1 . ILE   A 1 527 ? 173.067 147.611 173.198 1.00 58.83  ? 553 ILE   A CD1 1 
ATOM   4275 N N   . GLN   A 1 528 ? 170.197 150.599 175.631 1.00 59.04  ? 554 GLN   A N   1 
ATOM   4276 C CA  . GLN   A 1 528 ? 169.397 150.352 176.822 1.00 57.33  ? 554 GLN   A CA  1 
ATOM   4277 C C   . GLN   A 1 528 ? 168.677 149.022 176.667 1.00 62.75  ? 554 GLN   A C   1 
ATOM   4278 O O   . GLN   A 1 528 ? 168.233 148.676 175.568 1.00 72.57  ? 554 GLN   A O   1 
ATOM   4279 C CB  . GLN   A 1 528 ? 168.382 151.478 177.046 1.00 60.76  ? 554 GLN   A CB  1 
ATOM   4280 C CG  . GLN   A 1 528 ? 167.580 151.355 178.327 1.00 69.39  ? 554 GLN   A CG  1 
ATOM   4281 C CD  . GLN   A 1 528 ? 166.674 152.544 178.557 1.00 79.19  ? 554 GLN   A CD  1 
ATOM   4282 O OE1 . GLN   A 1 528 ? 166.673 153.497 177.780 1.00 80.43  ? 554 GLN   A OE1 1 
ATOM   4283 N NE2 . GLN   A 1 528 ? 165.893 152.495 179.629 1.00 82.83  ? 554 GLN   A NE2 1 
ATOM   4284 N N   . LEU   A 1 529 ? 168.554 148.290 177.770 1.00 61.08  ? 555 LEU   A N   1 
ATOM   4285 C CA  . LEU   A 1 529 ? 167.918 146.980 177.784 1.00 58.47  ? 555 LEU   A CA  1 
ATOM   4286 C C   . LEU   A 1 529 ? 166.512 147.106 178.352 1.00 67.70  ? 555 LEU   A C   1 
ATOM   4287 O O   . LEU   A 1 529 ? 166.325 147.654 179.443 1.00 78.37  ? 555 LEU   A O   1 
ATOM   4288 C CB  . LEU   A 1 529 ? 168.740 145.991 178.611 1.00 60.03  ? 555 LEU   A CB  1 
ATOM   4289 C CG  . LEU   A 1 529 ? 168.214 144.563 178.759 1.00 63.75  ? 555 LEU   A CG  1 
ATOM   4290 C CD1 . LEU   A 1 529 ? 168.133 143.860 177.413 1.00 67.31  ? 555 LEU   A CD1 1 
ATOM   4291 C CD2 . LEU   A 1 529 ? 169.094 143.787 179.719 1.00 69.76  ? 555 LEU   A CD2 1 
ATOM   4292 N N   . LEU   A 1 530 ? 165.529 146.599 177.609 1.00 66.38  ? 556 LEU   A N   1 
ATOM   4293 C CA  . LEU   A 1 530 ? 164.129 146.638 178.011 1.00 62.62  ? 556 LEU   A CA  1 
ATOM   4294 C C   . LEU   A 1 530 ? 163.667 145.351 178.678 1.00 69.44  ? 556 LEU   A C   1 
ATOM   4295 O O   . LEU   A 1 530 ? 162.927 145.407 179.665 1.00 76.45  ? 556 LEU   A O   1 
ATOM   4296 C CB  . LEU   A 1 530 ? 163.240 146.925 176.798 1.00 62.23  ? 556 LEU   A CB  1 
ATOM   4297 C CG  . LEU   A 1 530 ? 163.390 148.303 176.153 1.00 68.26  ? 556 LEU   A CG  1 
ATOM   4298 C CD1 . LEU   A 1 530 ? 162.634 148.354 174.836 1.00 75.79  ? 556 LEU   A CD1 1 
ATOM   4299 C CD2 . LEU   A 1 530 ? 162.902 149.400 177.084 1.00 65.78  ? 556 LEU   A CD2 1 
ATOM   4300 N N   . GLN   A 1 531 ? 164.076 144.194 178.164 1.00 69.71  ? 557 GLN   A N   1 
ATOM   4301 C CA  . GLN   A 1 531 ? 163.719 142.919 178.773 1.00 62.71  ? 557 GLN   A CA  1 
ATOM   4302 C C   . GLN   A 1 531 ? 164.832 141.919 178.510 1.00 73.60  ? 557 GLN   A C   1 
ATOM   4303 O O   . GLN   A 1 531 ? 165.393 141.884 177.413 1.00 80.56  ? 557 GLN   A O   1 
ATOM   4304 C CB  . GLN   A 1 531 ? 162.390 142.382 178.227 1.00 70.86  ? 557 GLN   A CB  1 
ATOM   4305 C CG  . GLN   A 1 531 ? 161.865 141.146 178.960 1.00 81.02  ? 557 GLN   A CG  1 
ATOM   4306 C CD  . GLN   A 1 531 ? 160.597 140.585 178.342 1.00 79.63  ? 557 GLN   A CD  1 
ATOM   4307 O OE1 . GLN   A 1 531 ? 159.597 141.288 178.199 1.00 74.69  ? 557 GLN   A OE1 1 
ATOM   4308 N NE2 . GLN   A 1 531 ? 160.634 139.310 177.971 1.00 71.68  ? 557 GLN   A NE2 1 
ATOM   4309 N N   . GLY   A 1 532 ? 165.139 141.112 179.516 1.00 75.98  ? 558 GLY   A N   1 
ATOM   4310 C CA  . GLY   A 1 532 ? 166.134 140.067 179.397 1.00 74.98  ? 558 GLY   A CA  1 
ATOM   4311 C C   . GLY   A 1 532 ? 167.468 140.461 179.996 1.00 78.80  ? 558 GLY   A C   1 
ATOM   4312 O O   . GLY   A 1 532 ? 167.581 141.383 180.808 1.00 83.47  ? 558 GLY   A O   1 
ATOM   4313 N N   . GLU   A 1 533 ? 168.502 139.733 179.577 1.00 83.48  ? 559 GLU   A N   1 
ATOM   4314 C CA  . GLU   A 1 533 ? 169.864 139.970 180.034 1.00 89.41  ? 559 GLU   A CA  1 
ATOM   4315 C C   . GLU   A 1 533 ? 170.817 139.751 178.870 1.00 84.23  ? 559 GLU   A C   1 
ATOM   4316 O O   . GLU   A 1 533 ? 170.808 138.683 178.252 1.00 83.04  ? 559 GLU   A O   1 
ATOM   4317 C CB  . GLU   A 1 533 ? 170.228 139.043 181.199 1.00 87.83  ? 559 GLU   A CB  1 
ATOM   4318 C CG  . GLU   A 1 533 ? 171.522 139.418 181.902 1.00 89.04  ? 559 GLU   A CG  1 
ATOM   4319 C CD  . GLU   A 1 533 ? 171.727 138.656 183.195 1.00 101.54 ? 559 GLU   A CD  1 
ATOM   4320 O OE1 . GLU   A 1 533 ? 170.965 137.700 183.451 1.00 107.67 ? 559 GLU   A OE1 1 
ATOM   4321 O OE2 . GLU   A 1 533 ? 172.649 139.014 183.957 1.00 104.50 ? 559 GLU   A OE2 1 
ATOM   4322 N N   . VAL   A 1 534 ? 171.633 140.766 178.578 1.00 71.93  ? 560 VAL   A N   1 
ATOM   4323 C CA  . VAL   A 1 534 ? 172.596 140.731 177.488 1.00 63.86  ? 560 VAL   A CA  1 
ATOM   4324 C C   . VAL   A 1 534 ? 173.957 141.139 178.033 1.00 67.71  ? 560 VAL   A C   1 
ATOM   4325 O O   . VAL   A 1 534 ? 174.084 141.632 179.155 1.00 74.79  ? 560 VAL   A O   1 
ATOM   4326 C CB  . VAL   A 1 534 ? 172.190 141.646 176.313 1.00 63.02  ? 560 VAL   A CB  1 
ATOM   4327 C CG1 . VAL   A 1 534 ? 170.767 141.354 175.876 1.00 70.32  ? 560 VAL   A CG1 1 
ATOM   4328 C CG2 . VAL   A 1 534 ? 172.348 143.109 176.684 1.00 65.08  ? 560 VAL   A CG2 1 
ATOM   4329 N N   . THR   A 1 535 ? 174.986 140.897 177.223 1.00 63.26  ? 561 THR   A N   1 
ATOM   4330 C CA  . THR   A 1 535 ? 176.340 141.359 177.504 1.00 60.52  ? 561 THR   A CA  1 
ATOM   4331 C C   . THR   A 1 535 ? 176.843 142.124 176.291 1.00 66.38  ? 561 THR   A C   1 
ATOM   4332 O O   . THR   A 1 535 ? 176.825 141.598 175.172 1.00 70.39  ? 561 THR   A O   1 
ATOM   4333 C CB  . THR   A 1 535 ? 177.274 140.194 177.839 1.00 61.00  ? 561 THR   A CB  1 
ATOM   4334 O OG1 . THR   A 1 535 ? 177.477 139.388 176.675 1.00 70.72  ? 561 THR   A OG1 1 
ATOM   4335 C CG2 . THR   A 1 535 ? 176.682 139.340 178.945 1.00 64.09  ? 561 THR   A CG2 1 
ATOM   4336 N N   . VAL   A 1 536 ? 177.276 143.362 176.513 1.00 60.90  ? 562 VAL   A N   1 
ATOM   4337 C CA  . VAL   A 1 536 ? 177.767 144.236 175.453 1.00 55.56  ? 562 VAL   A CA  1 
ATOM   4338 C C   . VAL   A 1 536 ? 179.284 144.264 175.536 1.00 60.00  ? 562 VAL   A C   1 
ATOM   4339 O O   . VAL   A 1 536 ? 179.845 144.623 176.578 1.00 66.25  ? 562 VAL   A O   1 
ATOM   4340 C CB  . VAL   A 1 536 ? 177.180 145.650 175.571 1.00 64.67  ? 562 VAL   A CB  1 
ATOM   4341 C CG1 . VAL   A 1 536 ? 177.711 146.540 174.453 1.00 66.00  ? 562 VAL   A CG1 1 
ATOM   4342 C CG2 . VAL   A 1 536 ? 175.655 145.598 175.553 1.00 65.10  ? 562 VAL   A CG2 1 
ATOM   4343 N N   . GLU   A 1 537 ? 179.939 143.893 174.438 1.00 63.12  ? 563 GLU   A N   1 
ATOM   4344 C CA  . GLU   A 1 537 ? 181.384 143.732 174.356 1.00 63.26  ? 563 GLU   A CA  1 
ATOM   4345 C C   . GLU   A 1 537 ? 181.971 144.780 173.422 1.00 68.55  ? 563 GLU   A C   1 
ATOM   4346 O O   . GLU   A 1 537 ? 181.547 144.894 172.266 1.00 71.34  ? 563 GLU   A O   1 
ATOM   4347 C CB  . GLU   A 1 537 ? 181.740 142.330 173.853 1.00 68.19  ? 563 GLU   A CB  1 
ATOM   4348 C CG  . GLU   A 1 537 ? 183.229 142.089 173.612 1.00 75.39  ? 563 GLU   A CG  1 
ATOM   4349 C CD  . GLU   A 1 537 ? 183.541 140.655 173.243 1.00 82.24  ? 563 GLU   A CD  1 
ATOM   4350 O OE1 . GLU   A 1 537 ? 182.680 139.777 173.463 1.00 86.17  ? 563 GLU   A OE1 1 
ATOM   4351 O OE2 . GLU   A 1 537 ? 184.650 140.406 172.726 1.00 80.74  ? 563 GLU   A OE2 1 
ATOM   4352 N N   . LEU   A 1 538 ? 182.944 145.536 173.927 1.00 69.75  ? 564 LEU   A N   1 
ATOM   4353 C CA  . LEU   A 1 538 ? 183.780 146.400 173.107 1.00 64.75  ? 564 LEU   A CA  1 
ATOM   4354 C C   . LEU   A 1 538 ? 185.036 145.626 172.728 1.00 77.46  ? 564 LEU   A C   1 
ATOM   4355 O O   . LEU   A 1 538 ? 185.758 145.131 173.606 1.00 84.43  ? 564 LEU   A O   1 
ATOM   4356 C CB  . LEU   A 1 538 ? 184.138 147.681 173.857 1.00 62.42  ? 564 LEU   A CB  1 
ATOM   4357 C CG  . LEU   A 1 538 ? 182.968 148.492 174.414 1.00 62.12  ? 564 LEU   A CG  1 
ATOM   4358 C CD1 . LEU   A 1 538 ? 183.479 149.711 175.154 1.00 65.14  ? 564 LEU   A CD1 1 
ATOM   4359 C CD2 . LEU   A 1 538 ? 182.011 148.901 173.309 1.00 67.60  ? 564 LEU   A CD2 1 
ATOM   4360 N N   . VAL   A 1 539 ? 185.284 145.514 171.419 1.00 76.78  ? 565 VAL   A N   1 
ATOM   4361 C CA  . VAL   A 1 539 ? 186.388 144.697 170.914 1.00 73.94  ? 565 VAL   A CA  1 
ATOM   4362 C C   . VAL   A 1 539 ? 187.714 145.437 170.873 1.00 72.75  ? 565 VAL   A C   1 
ATOM   4363 O O   . VAL   A 1 539 ? 188.761 144.793 170.730 1.00 81.07  ? 565 VAL   A O   1 
ATOM   4364 C CB  . VAL   A 1 539 ? 186.080 144.147 169.505 1.00 70.10  ? 565 VAL   A CB  1 
ATOM   4365 C CG1 . VAL   A 1 539 ? 184.900 143.192 169.559 1.00 75.09  ? 565 VAL   A CG1 1 
ATOM   4366 C CG2 . VAL   A 1 539 ? 185.811 145.264 168.492 1.00 63.00  ? 565 VAL   A CG2 1 
ATOM   4367 N N   . ALA   A 1 540 ? 187.705 146.766 170.984 1.00 70.02  ? 566 ALA   A N   1 
ATOM   4368 C CA  . ALA   A 1 540 ? 188.956 147.516 170.950 1.00 80.52  ? 566 ALA   A CA  1 
ATOM   4369 C C   . ALA   A 1 540 ? 189.852 147.147 172.126 1.00 86.71  ? 566 ALA   A C   1 
ATOM   4370 O O   . ALA   A 1 540 ? 191.071 147.017 171.967 1.00 88.02  ? 566 ALA   A O   1 
ATOM   4371 C CB  . ALA   A 1 540 ? 188.665 149.016 170.938 1.00 80.83  ? 566 ALA   A CB  1 
ATOM   4372 N N   . GLU   A 1 541 ? 189.263 146.974 173.313 1.00 84.85  ? 567 GLU   A N   1 
ATOM   4373 C CA  . GLU   A 1 541 ? 189.985 146.542 174.506 1.00 84.77  ? 567 GLU   A CA  1 
ATOM   4374 C C   . GLU   A 1 541 ? 189.513 145.185 175.019 1.00 90.26  ? 567 GLU   A C   1 
ATOM   4375 O O   . GLU   A 1 541 ? 189.995 144.735 176.066 1.00 93.85  ? 567 GLU   A O   1 
ATOM   4376 C CB  . GLU   A 1 541 ? 189.858 147.586 175.621 1.00 83.66  ? 567 GLU   A CB  1 
ATOM   4377 C CG  . GLU   A 1 541 ? 188.429 148.016 175.951 1.00 85.11  ? 567 GLU   A CG  1 
ATOM   4378 C CD  . GLU   A 1 541 ? 187.925 149.152 175.079 1.00 89.43  ? 567 GLU   A CD  1 
ATOM   4379 O OE1 . GLU   A 1 541 ? 188.593 149.487 174.080 1.00 90.43  ? 567 GLU   A OE1 1 
ATOM   4380 O OE2 . GLU   A 1 541 ? 186.855 149.713 175.397 1.00 97.41  ? 567 GLU   A OE2 1 
ATOM   4381 N N   . GLN   A 1 542 ? 188.598 144.518 174.310 1.00 88.85  ? 568 GLN   A N   1 
ATOM   4382 C CA  . GLN   A 1 542 ? 188.115 143.190 174.689 1.00 86.25  ? 568 GLN   A CA  1 
ATOM   4383 C C   . GLN   A 1 542 ? 187.498 143.210 176.087 1.00 88.34  ? 568 GLN   A C   1 
ATOM   4384 O O   . GLN   A 1 542 ? 187.863 142.422 176.962 1.00 85.90  ? 568 GLN   A O   1 
ATOM   4385 C CB  . GLN   A 1 542 ? 189.239 142.152 174.604 1.00 85.03  ? 568 GLN   A CB  1 
ATOM   4386 C CG  . GLN   A 1 542 ? 189.901 142.042 173.238 1.00 88.54  ? 568 GLN   A CG  1 
ATOM   4387 C CD  . GLN   A 1 542 ? 188.963 141.515 172.168 1.00 93.28  ? 568 GLN   A CD  1 
ATOM   4388 O OE1 . GLN   A 1 542 ? 187.880 141.012 172.468 1.00 89.26  ? 568 GLN   A OE1 1 
ATOM   4389 N NE2 . GLN   A 1 542 ? 189.377 141.627 170.911 1.00 87.50  ? 568 GLN   A NE2 1 
ATOM   4390 N N   . LYS   A 1 543 ? 186.548 144.123 176.290 1.00 86.13  ? 569 LYS   A N   1 
ATOM   4391 C CA  . LYS   A 1 543 ? 185.924 144.346 177.590 1.00 77.84  ? 569 LYS   A CA  1 
ATOM   4392 C C   . LYS   A 1 543 ? 184.415 144.295 177.426 1.00 76.74  ? 569 LYS   A C   1 
ATOM   4393 O O   . LYS   A 1 543 ? 183.862 145.023 176.597 1.00 81.21  ? 569 LYS   A O   1 
ATOM   4394 C CB  . LYS   A 1 543 ? 186.351 145.699 178.172 1.00 82.01  ? 569 LYS   A CB  1 
ATOM   4395 C CG  . LYS   A 1 543 ? 185.840 145.986 179.581 1.00 87.19  ? 569 LYS   A CG  1 
ATOM   4396 C CD  . LYS   A 1 543 ? 186.185 147.401 180.031 1.00 90.89  ? 569 LYS   A CD  1 
ATOM   4397 C CE  . LYS   A 1 543 ? 187.671 147.571 180.303 1.00 92.99  ? 569 LYS   A CE  1 
ATOM   4398 N NZ  . LYS   A 1 543 ? 187.986 148.933 180.816 1.00 91.90  ? 569 LYS   A NZ  1 
ATOM   4399 N N   . ASN   A 1 544 ? 183.753 143.442 178.209 1.00 76.99  ? 570 ASN   A N   1 
ATOM   4400 C CA  . ASN   A 1 544 ? 182.308 143.272 178.133 1.00 81.32  ? 570 ASN   A CA  1 
ATOM   4401 C C   . ASN   A 1 544 ? 181.651 143.568 179.473 1.00 78.89  ? 570 ASN   A C   1 
ATOM   4402 O O   . ASN   A 1 544 ? 182.198 143.248 180.532 1.00 77.34  ? 570 ASN   A O   1 
ATOM   4403 C CB  . ASN   A 1 544 ? 181.926 141.859 177.661 1.00 81.77  ? 570 ASN   A CB  1 
ATOM   4404 C CG  . ASN   A 1 544 ? 182.595 140.761 178.465 1.00 78.66  ? 570 ASN   A CG  1 
ATOM   4405 O OD1 . ASN   A 1 544 ? 183.211 141.011 179.499 1.00 84.76  ? 570 ASN   A OD1 1 
ATOM   4406 N ND2 . ASN   A 1 544 ? 182.471 139.527 177.986 1.00 70.16  ? 570 ASN   A ND2 1 
ATOM   4407 N N   . GLN   A 1 545 ? 180.476 144.192 179.405 1.00 79.95  ? 571 GLN   A N   1 
ATOM   4408 C CA  . GLN   A 1 545 ? 179.647 144.482 180.567 1.00 75.29  ? 571 GLN   A CA  1 
ATOM   4409 C C   . GLN   A 1 545 ? 178.320 143.747 180.449 1.00 78.34  ? 571 GLN   A C   1 
ATOM   4410 O O   . GLN   A 1 545 ? 177.700 143.733 179.380 1.00 80.58  ? 571 GLN   A O   1 
ATOM   4411 C CB  . GLN   A 1 545 ? 179.383 145.981 180.708 1.00 76.58  ? 571 GLN   A CB  1 
ATOM   4412 C CG  . GLN   A 1 545 ? 180.569 146.782 181.210 1.00 83.03  ? 571 GLN   A CG  1 
ATOM   4413 C CD  . GLN   A 1 545 ? 180.175 148.167 181.681 1.00 87.61  ? 571 GLN   A CD  1 
ATOM   4414 O OE1 . GLN   A 1 545 ? 179.012 148.562 181.587 1.00 81.06  ? 571 GLN   A OE1 1 
ATOM   4415 N NE2 . GLN   A 1 545 ? 181.143 148.913 182.198 1.00 88.15  ? 571 GLN   A NE2 1 
ATOM   4416 N N   . THR   A 1 546 ? 177.888 143.152 181.559 1.00 71.74  ? 572 THR   A N   1 
ATOM   4417 C CA  . THR   A 1 546 ? 176.630 142.419 181.624 1.00 72.39  ? 572 THR   A CA  1 
ATOM   4418 C C   . THR   A 1 546 ? 175.532 143.362 182.099 1.00 73.89  ? 572 THR   A C   1 
ATOM   4419 O O   . THR   A 1 546 ? 175.577 143.849 183.233 1.00 79.32  ? 572 THR   A O   1 
ATOM   4420 C CB  . THR   A 1 546 ? 176.750 141.224 182.566 1.00 80.44  ? 572 THR   A CB  1 
ATOM   4421 O OG1 . THR   A 1 546 ? 177.089 141.681 183.881 1.00 88.14  ? 572 THR   A OG1 1 
ATOM   4422 C CG2 . THR   A 1 546 ? 177.822 140.257 182.079 1.00 77.65  ? 572 THR   A CG2 1 
ATOM   4423 N N   . LEU   A 1 547 ? 174.549 143.613 181.238 1.00 72.56  ? 573 LEU   A N   1 
ATOM   4424 C CA  . LEU   A 1 547 ? 173.526 144.618 181.488 1.00 76.53  ? 573 LEU   A CA  1 
ATOM   4425 C C   . LEU   A 1 547 ? 172.259 143.968 182.023 1.00 89.56  ? 573 LEU   A C   1 
ATOM   4426 O O   . LEU   A 1 547 ? 171.888 142.865 181.608 1.00 89.50  ? 573 LEU   A O   1 
ATOM   4427 C CB  . LEU   A 1 547 ? 173.211 145.395 180.207 1.00 69.33  ? 573 LEU   A CB  1 
ATOM   4428 C CG  . LEU   A 1 547 ? 174.093 146.605 179.887 1.00 64.39  ? 573 LEU   A CG  1 
ATOM   4429 C CD1 . LEU   A 1 547 ? 175.570 146.248 179.905 1.00 72.67  ? 573 LEU   A CD1 1 
ATOM   4430 C CD2 . LEU   A 1 547 ? 173.712 147.183 178.544 1.00 61.95  ? 573 LEU   A CD2 1 
ATOM   4431 N N   . ARG   A 1 548 ? 171.603 144.659 182.952 1.00 98.01  ? 574 ARG   A N   1 
ATOM   4432 C CA  . ARG   A 1 548 ? 170.321 144.269 183.520 1.00 90.16  ? 574 ARG   A CA  1 
ATOM   4433 C C   . ARG   A 1 548 ? 169.239 145.211 182.996 1.00 82.78  ? 574 ARG   A C   1 
ATOM   4434 O O   . ARG   A 1 548 ? 169.515 146.159 182.256 1.00 86.53  ? 574 ARG   A O   1 
ATOM   4435 C CB  . ARG   A 1 548 ? 170.392 144.279 185.051 1.00 93.94  ? 574 ARG   A CB  1 
ATOM   4436 C CG  . ARG   A 1 548 ? 170.785 142.941 185.672 1.00 105.82 ? 574 ARG   A CG  1 
ATOM   4437 C CD  . ARG   A 1 548 ? 172.176 142.488 185.247 1.00 107.80 ? 574 ARG   A CD  1 
ATOM   4438 N NE  . ARG   A 1 548 ? 172.568 141.241 185.896 1.00 113.26 ? 574 ARG   A NE  1 
ATOM   4439 C CZ  . ARG   A 1 548 ? 173.089 141.140 187.113 1.00 118.67 ? 574 ARG   A CZ  1 
ATOM   4440 N NH1 . ARG   A 1 548 ? 173.294 142.203 187.876 1.00 115.46 ? 574 ARG   A NH1 1 
ATOM   4441 N NH2 . ARG   A 1 548 ? 173.412 139.937 187.580 1.00 122.68 ? 574 ARG   A NH2 1 
ATOM   4442 N N   . GLU   A 1 549 ? 167.994 144.936 183.377 1.00 74.96  ? 575 GLU   A N   1 
ATOM   4443 C CA  . GLU   A 1 549 ? 166.881 145.748 182.906 1.00 78.98  ? 575 GLU   A CA  1 
ATOM   4444 C C   . GLU   A 1 549 ? 167.000 147.174 183.424 1.00 77.28  ? 575 GLU   A C   1 
ATOM   4445 O O   . GLU   A 1 549 ? 167.397 147.409 184.569 1.00 83.67  ? 575 GLU   A O   1 
ATOM   4446 C CB  . GLU   A 1 549 ? 165.552 145.139 183.351 1.00 85.70  ? 575 GLU   A CB  1 
ATOM   4447 C CG  . GLU   A 1 549 ? 165.176 143.867 182.610 1.00 86.01  ? 575 GLU   A CG  1 
ATOM   4448 C CD  . GLU   A 1 549 ? 163.789 143.374 182.967 1.00 88.26  ? 575 GLU   A CD  1 
ATOM   4449 O OE1 . GLU   A 1 549 ? 163.218 143.868 183.961 1.00 89.16  ? 575 GLU   A OE1 1 
ATOM   4450 O OE2 . GLU   A 1 549 ? 163.268 142.494 182.251 1.00 86.28  ? 575 GLU   A OE2 1 
ATOM   4451 N N   . GLY   A 1 550 ? 166.654 148.129 182.569 1.00 74.31  ? 576 GLY   A N   1 
ATOM   4452 C CA  . GLY   A 1 550 ? 166.717 149.533 182.933 1.00 83.96  ? 576 GLY   A CA  1 
ATOM   4453 C C   . GLY   A 1 550 ? 168.117 150.045 183.193 1.00 85.91  ? 576 GLY   A C   1 
ATOM   4454 O O   . GLY   A 1 550 ? 168.309 150.883 184.084 1.00 92.78  ? 576 GLY   A O   1 
ATOM   4455 N N   . GLU   A 1 551 ? 169.100 149.561 182.436 1.00 78.86  ? 577 GLU   A N   1 
ATOM   4456 C CA  . GLU   A 1 551 ? 170.468 150.055 182.479 1.00 72.73  ? 577 GLU   A CA  1 
ATOM   4457 C C   . GLU   A 1 551 ? 170.866 150.543 181.094 1.00 70.71  ? 577 GLU   A C   1 
ATOM   4458 O O   . GLU   A 1 551 ? 170.436 149.991 180.078 1.00 78.38  ? 577 GLU   A O   1 
ATOM   4459 C CB  . GLU   A 1 551 ? 171.443 148.975 182.957 1.00 73.20  ? 577 GLU   A CB  1 
ATOM   4460 C CG  . GLU   A 1 551 ? 171.388 148.716 184.450 1.00 78.08  ? 577 GLU   A CG  1 
ATOM   4461 C CD  . GLU   A 1 551 ? 172.433 147.717 184.911 1.00 91.48  ? 577 GLU   A CD  1 
ATOM   4462 O OE1 . GLU   A 1 551 ? 173.283 147.317 184.089 1.00 86.45  ? 577 GLU   A OE1 1 
ATOM   4463 O OE2 . GLU   A 1 551 ? 172.402 147.332 186.098 1.00 100.51 ? 577 GLU   A OE2 1 
ATOM   4464 N N   . LYS   A 1 552 ? 171.694 151.583 181.069 1.00 62.12  ? 578 LYS   A N   1 
ATOM   4465 C CA  . LYS   A 1 552 ? 172.073 152.272 179.845 1.00 65.15  ? 578 LYS   A CA  1 
ATOM   4466 C C   . LYS   A 1 552 ? 173.589 152.348 179.758 1.00 68.49  ? 578 LYS   A C   1 
ATOM   4467 O O   . LYS   A 1 552 ? 174.268 152.516 180.775 1.00 77.47  ? 578 LYS   A O   1 
ATOM   4468 C CB  . LYS   A 1 552 ? 171.468 153.682 179.805 1.00 74.15  ? 578 LYS   A CB  1 
ATOM   4469 C CG  . LYS   A 1 552 ? 171.485 154.335 178.431 1.00 74.87  ? 578 LYS   A CG  1 
ATOM   4470 C CD  . LYS   A 1 552 ? 170.672 155.626 178.402 1.00 74.28  ? 578 LYS   A CD  1 
ATOM   4471 C CE  . LYS   A 1 552 ? 171.323 156.729 179.220 1.00 80.01  ? 578 LYS   A CE  1 
ATOM   4472 N NZ  . LYS   A 1 552 ? 170.585 158.017 179.102 1.00 90.88  ? 578 LYS   A NZ  1 
ATOM   4473 N N   . MET   A 1 553 ? 174.111 152.217 178.539 1.00 65.71  ? 579 MET   A N   1 
ATOM   4474 C CA  . MET   A 1 553 ? 175.539 152.321 178.273 1.00 59.60  ? 579 MET   A CA  1 
ATOM   4475 C C   . MET   A 1 553 ? 175.760 153.272 177.108 1.00 61.98  ? 579 MET   A C   1 
ATOM   4476 O O   . MET   A 1 553 ? 174.989 153.284 176.146 1.00 64.67  ? 579 MET   A O   1 
ATOM   4477 C CB  . MET   A 1 553 ? 176.149 150.945 177.957 1.00 62.84  ? 579 MET   A CB  1 
ATOM   4478 C CG  . MET   A 1 553 ? 177.656 150.942 177.725 1.00 69.48  ? 579 MET   A CG  1 
ATOM   4479 S SD  . MET   A 1 553 ? 178.286 149.287 177.384 1.00 92.76  ? 579 MET   A SD  1 
ATOM   4480 C CE  . MET   A 1 553 ? 180.016 149.625 177.067 1.00 73.37  ? 579 MET   A CE  1 
ATOM   4481 N N   . GLN   A 1 554 ? 176.830 154.063 177.202 1.00 61.59  ? 580 GLN   A N   1 
ATOM   4482 C CA  . GLN   A 1 554 ? 177.193 155.053 176.187 1.00 60.61  ? 580 GLN   A CA  1 
ATOM   4483 C C   . GLN   A 1 554 ? 178.307 154.448 175.337 1.00 61.16  ? 580 GLN   A C   1 
ATOM   4484 O O   . GLN   A 1 554 ? 179.466 154.398 175.756 1.00 64.10  ? 580 GLN   A O   1 
ATOM   4485 C CB  . GLN   A 1 554 ? 177.630 156.359 176.841 1.00 61.57  ? 580 GLN   A CB  1 
ATOM   4486 C CG  . GLN   A 1 554 ? 177.610 157.563 175.916 1.00 60.75  ? 580 GLN   A CG  1 
ATOM   4487 C CD  . GLN   A 1 554 ? 176.221 158.135 175.725 1.00 62.81  ? 580 GLN   A CD  1 
ATOM   4488 O OE1 . GLN   A 1 554 ? 175.236 157.583 176.213 1.00 64.44  ? 580 GLN   A OE1 1 
ATOM   4489 N NE2 . GLN   A 1 554 ? 176.135 159.250 175.012 1.00 64.29  ? 580 GLN   A NE2 1 
ATOM   4490 N N   . LEU   A 1 555 ? 177.952 153.989 174.143 1.00 59.29  ? 581 LEU   A N   1 
ATOM   4491 C CA  . LEU   A 1 555 ? 178.855 153.193 173.332 1.00 54.83  ? 581 LEU   A CA  1 
ATOM   4492 C C   . LEU   A 1 555 ? 179.907 154.062 172.643 1.00 58.05  ? 581 LEU   A C   1 
ATOM   4493 O O   . LEU   A 1 555 ? 179.729 155.274 172.505 1.00 61.85  ? 581 LEU   A O   1 
ATOM   4494 C CB  . LEU   A 1 555 ? 178.067 152.418 172.285 1.00 52.18  ? 581 LEU   A CB  1 
ATOM   4495 C CG  . LEU   A 1 555 ? 177.051 151.407 172.814 1.00 59.51  ? 581 LEU   A CG  1 
ATOM   4496 C CD1 . LEU   A 1 555 ? 176.143 150.953 171.689 1.00 61.91  ? 581 LEU   A CD1 1 
ATOM   4497 C CD2 . LEU   A 1 555 ? 177.750 150.220 173.459 1.00 61.99  ? 581 LEU   A CD2 1 
ATOM   4498 N N   . PRO   A 1 556 ? 181.019 153.469 172.198 1.00 62.21  ? 582 PRO   A N   1 
ATOM   4499 C CA  . PRO   A 1 556 ? 181.954 154.222 171.355 1.00 60.68  ? 582 PRO   A CA  1 
ATOM   4500 C C   . PRO   A 1 556 ? 181.357 154.513 169.989 1.00 69.55  ? 582 PRO   A C   1 
ATOM   4501 O O   . PRO   A 1 556 ? 180.489 153.789 169.496 1.00 78.64  ? 582 PRO   A O   1 
ATOM   4502 C CB  . PRO   A 1 556 ? 183.166 153.291 171.233 1.00 59.82  ? 582 PRO   A CB  1 
ATOM   4503 C CG  . PRO   A 1 556 ? 183.010 152.281 172.292 1.00 63.69  ? 582 PRO   A CG  1 
ATOM   4504 C CD  . PRO   A 1 556 ? 181.547 152.131 172.515 1.00 67.39  ? 582 PRO   A CD  1 
ATOM   4505 N N   . ALA   A 1 557 ? 181.838 155.593 169.377 1.00 61.90  ? 583 ALA   A N   1 
ATOM   4506 C CA  . ALA   A 1 557 ? 181.501 155.954 168.006 1.00 59.60  ? 583 ALA   A CA  1 
ATOM   4507 C C   . ALA   A 1 557 ? 182.753 155.820 167.150 1.00 60.48  ? 583 ALA   A C   1 
ATOM   4508 O O   . ALA   A 1 557 ? 183.776 156.448 167.443 1.00 63.39  ? 583 ALA   A O   1 
ATOM   4509 C CB  . ALA   A 1 557 ? 180.945 157.375 167.933 1.00 66.98  ? 583 ALA   A CB  1 
ATOM   4510 N N   . GLY   A 1 558 ? 182.667 155.007 166.098 1.00 66.49  ? 584 GLY   A N   1 
ATOM   4511 C CA  . GLY   A 1 558 ? 183.774 154.766 165.191 1.00 71.86  ? 584 GLY   A CA  1 
ATOM   4512 C C   . GLY   A 1 558 ? 184.461 153.425 165.351 1.00 71.54  ? 584 GLY   A C   1 
ATOM   4513 O O   . GLY   A 1 558 ? 185.462 153.184 164.665 1.00 65.97  ? 584 GLY   A O   1 
ATOM   4514 N N   . GLU   A 1 559 ? 183.962 152.544 166.217 1.00 71.79  ? 585 GLU   A N   1 
ATOM   4515 C CA  . GLU   A 1 559 ? 184.527 151.219 166.446 1.00 57.54  ? 585 GLU   A CA  1 
ATOM   4516 C C   . GLU   A 1 559 ? 183.405 150.189 166.381 1.00 61.90  ? 585 GLU   A C   1 
ATOM   4517 O O   . GLU   A 1 559 ? 182.238 150.523 166.160 1.00 63.98  ? 585 GLU   A O   1 
ATOM   4518 C CB  . GLU   A 1 559 ? 185.246 151.147 167.799 1.00 59.06  ? 585 GLU   A CB  1 
ATOM   4519 C CG  . GLU   A 1 559 ? 186.363 152.159 167.975 1.00 73.42  ? 585 GLU   A CG  1 
ATOM   4520 C CD  . GLU   A 1 559 ? 187.018 152.063 169.339 1.00 82.71  ? 585 GLU   A CD  1 
ATOM   4521 O OE1 . GLU   A 1 559 ? 186.579 151.222 170.150 1.00 79.89  ? 585 GLU   A OE1 1 
ATOM   4522 O OE2 . GLU   A 1 559 ? 187.971 152.826 169.600 1.00 87.16  ? 585 GLU   A OE2 1 
ATOM   4523 N N   . TYR   A 1 560 ? 183.767 148.923 166.581 1.00 64.14  ? 586 TYR   A N   1 
ATOM   4524 C CA  . TYR   A 1 560 ? 182.816 147.821 166.591 1.00 55.31  ? 586 TYR   A CA  1 
ATOM   4525 C C   . TYR   A 1 560 ? 182.420 147.498 168.022 1.00 53.78  ? 586 TYR   A C   1 
ATOM   4526 O O   . TYR   A 1 560 ? 183.236 147.604 168.942 1.00 55.99  ? 586 TYR   A O   1 
ATOM   4527 C CB  . TYR   A 1 560 ? 183.401 146.559 165.950 1.00 51.06  ? 586 TYR   A CB  1 
ATOM   4528 C CG  . TYR   A 1 560 ? 183.854 146.701 164.518 1.00 52.04  ? 586 TYR   A CG  1 
ATOM   4529 C CD1 . TYR   A 1 560 ? 185.116 147.186 164.215 1.00 58.91  ? 586 TYR   A CD1 1 
ATOM   4530 C CD2 . TYR   A 1 560 ? 183.029 146.329 163.471 1.00 49.97  ? 586 TYR   A CD2 1 
ATOM   4531 C CE1 . TYR   A 1 560 ? 185.537 147.310 162.911 1.00 57.25  ? 586 TYR   A CE1 1 
ATOM   4532 C CE2 . TYR   A 1 560 ? 183.441 146.451 162.164 1.00 58.87  ? 586 TYR   A CE2 1 
ATOM   4533 C CZ  . TYR   A 1 560 ? 184.696 146.941 161.890 1.00 66.00  ? 586 TYR   A CZ  1 
ATOM   4534 O OH  . TYR   A 1 560 ? 185.116 147.064 160.586 1.00 79.70  ? 586 TYR   A OH  1 
ATOM   4535 N N   . HIS   A 1 561 ? 181.162 147.113 168.204 1.00 56.28  ? 587 HIS   A N   1 
ATOM   4536 C CA  . HIS   A 1 561 ? 180.718 146.465 169.426 1.00 50.81  ? 587 HIS   A CA  1 
ATOM   4537 C C   . HIS   A 1 561 ? 179.894 145.240 169.059 1.00 56.68  ? 587 HIS   A C   1 
ATOM   4538 O O   . HIS   A 1 561 ? 179.458 145.075 167.914 1.00 66.53  ? 587 HIS   A O   1 
ATOM   4539 C CB  . HIS   A 1 561 ? 179.911 147.411 170.327 1.00 47.45  ? 587 HIS   A CB  1 
ATOM   4540 C CG  . HIS   A 1 561 ? 178.551 147.749 169.803 1.00 51.42  ? 587 HIS   A CG  1 
ATOM   4541 N ND1 . HIS   A 1 561 ? 178.306 148.867 169.039 1.00 57.71  ? 587 HIS   A ND1 1 
ATOM   4542 C CD2 . HIS   A 1 561 ? 177.357 147.130 169.957 1.00 54.85  ? 587 HIS   A CD2 1 
ATOM   4543 C CE1 . HIS   A 1 561 ? 177.023 148.916 168.731 1.00 58.54  ? 587 HIS   A CE1 1 
ATOM   4544 N NE2 . HIS   A 1 561 ? 176.425 147.872 169.274 1.00 54.52  ? 587 HIS   A NE2 1 
ATOM   4545 N N   . LYS   A 1 562 ? 179.722 144.362 170.041 1.00 55.00  ? 588 LYS   A N   1 
ATOM   4546 C CA  . LYS   A 1 562 ? 178.898 143.171 169.905 1.00 54.12  ? 588 LYS   A CA  1 
ATOM   4547 C C   . LYS   A 1 562 ? 177.927 143.112 171.072 1.00 60.76  ? 588 LYS   A C   1 
ATOM   4548 O O   . LYS   A 1 562 ? 178.240 143.582 172.167 1.00 68.93  ? 588 LYS   A O   1 
ATOM   4549 C CB  . LYS   A 1 562 ? 179.748 141.902 169.871 1.00 58.38  ? 588 LYS   A CB  1 
ATOM   4550 C CG  . LYS   A 1 562 ? 180.704 141.825 168.700 1.00 65.77  ? 588 LYS   A CG  1 
ATOM   4551 C CD  . LYS   A 1 562 ? 181.481 140.521 168.711 1.00 73.38  ? 588 LYS   A CD  1 
ATOM   4552 C CE  . LYS   A 1 562 ? 182.410 140.419 167.514 1.00 73.95  ? 588 LYS   A CE  1 
ATOM   4553 N NZ  . LYS   A 1 562 ? 183.166 139.136 167.491 1.00 75.97  ? 588 LYS   A NZ  1 
ATOM   4554 N N   . VAL   A 1 563 ? 176.739 142.565 170.828 1.00 58.07  ? 589 VAL   A N   1 
ATOM   4555 C CA  . VAL   A 1 563 ? 175.762 142.300 171.881 1.00 55.50  ? 589 VAL   A CA  1 
ATOM   4556 C C   . VAL   A 1 563 ? 175.408 140.820 171.830 1.00 59.02  ? 589 VAL   A C   1 
ATOM   4557 O O   . VAL   A 1 563 ? 174.959 140.315 170.792 1.00 67.66  ? 589 VAL   A O   1 
ATOM   4558 C CB  . VAL   A 1 563 ? 174.515 143.194 171.761 1.00 55.33  ? 589 VAL   A CB  1 
ATOM   4559 C CG1 . VAL   A 1 563 ? 174.904 144.651 171.898 1.00 60.36  ? 589 VAL   A CG1 1 
ATOM   4560 C CG2 . VAL   A 1 563 ? 173.781 142.979 170.457 1.00 60.44  ? 589 VAL   A CG2 1 
ATOM   4561 N N   . TYR   A 1 564 ? 175.664 140.121 172.937 1.00 57.34  ? 590 TYR   A N   1 
ATOM   4562 C CA  . TYR   A 1 564 ? 175.379 138.701 173.087 1.00 56.04  ? 590 TYR   A CA  1 
ATOM   4563 C C   . TYR   A 1 564 ? 174.170 138.524 173.993 1.00 71.53  ? 590 TYR   A C   1 
ATOM   4564 O O   . TYR   A 1 564 ? 174.075 139.178 175.038 1.00 81.04  ? 590 TYR   A O   1 
ATOM   4565 C CB  . TYR   A 1 564 ? 176.566 137.953 173.694 1.00 56.56  ? 590 TYR   A CB  1 
ATOM   4566 C CG  . TYR   A 1 564 ? 177.857 138.029 172.918 1.00 55.07  ? 590 TYR   A CG  1 
ATOM   4567 C CD1 . TYR   A 1 564 ? 178.679 139.140 173.003 1.00 60.64  ? 590 TYR   A CD1 1 
ATOM   4568 C CD2 . TYR   A 1 564 ? 178.272 136.970 172.128 1.00 67.47  ? 590 TYR   A CD2 1 
ATOM   4569 C CE1 . TYR   A 1 564 ? 179.864 139.204 172.303 1.00 70.05  ? 590 TYR   A CE1 1 
ATOM   4570 C CE2 . TYR   A 1 564 ? 179.453 137.024 171.425 1.00 70.51  ? 590 TYR   A CE2 1 
ATOM   4571 C CZ  . TYR   A 1 564 ? 180.247 138.142 171.517 1.00 74.63  ? 590 TYR   A CZ  1 
ATOM   4572 O OH  . TYR   A 1 564 ? 181.429 138.194 170.816 1.00 84.52  ? 590 TYR   A OH  1 
ATOM   4573 N N   . THR   A 1 565 ? 173.260 137.636 173.598 1.00 72.54  ? 591 THR   A N   1 
ATOM   4574 C CA  . THR   A 1 565 ? 172.118 137.257 174.420 1.00 72.94  ? 591 THR   A CA  1 
ATOM   4575 C C   . THR   A 1 565 ? 172.450 135.947 175.123 1.00 75.18  ? 591 THR   A C   1 
ATOM   4576 O O   . THR   A 1 565 ? 172.794 134.957 174.468 1.00 77.34  ? 591 THR   A O   1 
ATOM   4577 C CB  . THR   A 1 565 ? 170.857 137.111 173.573 1.00 71.04  ? 591 THR   A CB  1 
ATOM   4578 O OG1 . THR   A 1 565 ? 170.706 138.264 172.738 1.00 69.83  ? 591 THR   A OG1 1 
ATOM   4579 C CG2 . THR   A 1 565 ? 169.630 136.972 174.459 1.00 72.08  ? 591 THR   A CG2 1 
ATOM   4580 N N   . THR   A 1 566 ? 172.351 135.946 176.451 1.00 77.90  ? 592 THR   A N   1 
ATOM   4581 C CA  . THR   A 1 566 ? 172.769 134.830 177.297 1.00 77.59  ? 592 THR   A CA  1 
ATOM   4582 C C   . THR   A 1 566 ? 171.710 134.523 178.347 1.00 82.76  ? 592 THR   A C   1 
ATOM   4583 O O   . THR   A 1 566 ? 172.007 134.361 179.533 1.00 80.54  ? 592 THR   A O   1 
ATOM   4584 C CB  . THR   A 1 566 ? 174.106 135.134 177.965 1.00 77.70  ? 592 THR   A CB  1 
ATOM   4585 O OG1 . THR   A 1 566 ? 173.997 136.340 178.731 1.00 74.21  ? 592 THR   A OG1 1 
ATOM   4586 C CG2 . THR   A 1 566 ? 175.202 135.294 176.921 1.00 80.42  ? 592 THR   A CG2 1 
ATOM   4587 N N   . SER   A 1 567 ? 170.456 134.442 177.919 1.00 86.80  ? 593 SER   A N   1 
ATOM   4588 C CA  . SER   A 1 567 ? 169.311 134.170 178.774 1.00 81.02  ? 593 SER   A CA  1 
ATOM   4589 C C   . SER   A 1 567 ? 168.512 133.016 178.189 1.00 74.99  ? 593 SER   A C   1 
ATOM   4590 O O   . SER   A 1 567 ? 168.653 132.699 177.004 1.00 73.08  ? 593 SER   A O   1 
ATOM   4591 C CB  . SER   A 1 567 ? 168.412 135.408 178.913 1.00 80.22  ? 593 SER   A CB  1 
ATOM   4592 O OG  . SER   A 1 567 ? 167.944 135.847 177.650 1.00 80.08  ? 593 SER   A OG  1 
ATOM   4593 N N   . PRO   A 1 568 ? 167.683 132.344 178.997 1.00 79.37  ? 594 PRO   A N   1 
ATOM   4594 C CA  . PRO   A 1 568 ? 166.838 131.275 178.433 1.00 79.59  ? 594 PRO   A CA  1 
ATOM   4595 C C   . PRO   A 1 568 ? 165.832 131.759 177.401 1.00 79.32  ? 594 PRO   A C   1 
ATOM   4596 O O   . PRO   A 1 568 ? 165.368 130.944 176.594 1.00 82.63  ? 594 PRO   A O   1 
ATOM   4597 C CB  . PRO   A 1 568 ? 166.126 130.697 179.664 1.00 86.21  ? 594 PRO   A CB  1 
ATOM   4598 C CG  . PRO   A 1 568 ? 166.943 131.106 180.820 1.00 86.31  ? 594 PRO   A CG  1 
ATOM   4599 C CD  . PRO   A 1 568 ? 167.534 132.426 180.461 1.00 86.15  ? 594 PRO   A CD  1 
ATOM   4600 N N   . SER   A 1 569 ? 165.481 133.041 177.400 1.00 78.42  ? 595 SER   A N   1 
ATOM   4601 C CA  . SER   A 1 569 ? 164.436 133.610 176.566 1.00 72.15  ? 595 SER   A CA  1 
ATOM   4602 C C   . SER   A 1 569 ? 164.985 134.774 175.748 1.00 69.15  ? 595 SER   A C   1 
ATOM   4603 O O   . SER   A 1 569 ? 166.062 135.299 176.053 1.00 76.59  ? 595 SER   A O   1 
ATOM   4604 C CB  . SER   A 1 569 ? 163.260 134.091 177.429 1.00 80.77  ? 595 SER   A CB  1 
ATOM   4605 O OG  . SER   A 1 569 ? 163.679 135.079 178.353 1.00 87.58  ? 595 SER   A OG  1 
ATOM   4606 N N   . PRO   A 1 570 ? 164.281 135.199 174.692 1.00 58.80  ? 596 PRO   A N   1 
ATOM   4607 C CA  . PRO   A 1 570 ? 164.784 136.318 173.884 1.00 63.74  ? 596 PRO   A CA  1 
ATOM   4608 C C   . PRO   A 1 570 ? 164.877 137.606 174.687 1.00 69.30  ? 596 PRO   A C   1 
ATOM   4609 O O   . PRO   A 1 570 ? 164.145 137.812 175.658 1.00 73.21  ? 596 PRO   A O   1 
ATOM   4610 C CB  . PRO   A 1 570 ? 163.749 136.442 172.760 1.00 64.64  ? 596 PRO   A CB  1 
ATOM   4611 C CG  . PRO   A 1 570 ? 163.073 135.140 172.706 1.00 68.28  ? 596 PRO   A CG  1 
ATOM   4612 C CD  . PRO   A 1 570 ? 163.060 134.620 174.103 1.00 68.73  ? 596 PRO   A CD  1 
ATOM   4613 N N   . SER   A 1 571 ? 165.795 138.475 174.265 1.00 68.40  ? 597 SER   A N   1 
ATOM   4614 C CA  . SER   A 1 571 ? 166.054 139.749 174.925 1.00 63.51  ? 597 SER   A CA  1 
ATOM   4615 C C   . SER   A 1 571 ? 165.696 140.897 173.993 1.00 59.20  ? 597 SER   A C   1 
ATOM   4616 O O   . SER   A 1 571 ? 165.998 140.853 172.798 1.00 68.84  ? 597 SER   A O   1 
ATOM   4617 C CB  . SER   A 1 571 ? 167.522 139.858 175.343 1.00 70.72  ? 597 SER   A CB  1 
ATOM   4618 O OG  . SER   A 1 571 ? 168.381 139.748 174.221 1.00 74.03  ? 597 SER   A OG  1 
ATOM   4619 N N   . CYS   A 1 572 ? 165.067 141.931 174.549 1.00 56.76  ? 598 CYS   A N   1 
ATOM   4620 C CA  . CYS   A 1 572 ? 164.663 143.119 173.806 1.00 63.42  ? 598 CYS   A CA  1 
ATOM   4621 C C   . CYS   A 1 572 ? 165.407 144.332 174.341 1.00 67.62  ? 598 CYS   A C   1 
ATOM   4622 O O   . CYS   A 1 572 ? 165.371 144.600 175.549 1.00 75.93  ? 598 CYS   A O   1 
ATOM   4623 C CB  . CYS   A 1 572 ? 163.156 143.351 173.909 1.00 66.77  ? 598 CYS   A CB  1 
ATOM   4624 S SG  . CYS   A 1 572 ? 162.157 142.128 173.041 1.00 104.01 ? 598 CYS   A SG  1 
ATOM   4625 N N   . TYR   A 1 573 ? 166.064 145.064 173.438 1.00 63.71  ? 599 TYR   A N   1 
ATOM   4626 C CA  . TYR   A 1 573 ? 166.813 146.266 173.781 1.00 57.98  ? 599 TYR   A CA  1 
ATOM   4627 C C   . TYR   A 1 573 ? 166.614 147.304 172.680 1.00 56.48  ? 599 TYR   A C   1 
ATOM   4628 O O   . TYR   A 1 573 ? 165.904 147.068 171.696 1.00 67.58  ? 599 TYR   A O   1 
ATOM   4629 C CB  . TYR   A 1 573 ? 168.296 145.942 174.015 1.00 59.13  ? 599 TYR   A CB  1 
ATOM   4630 C CG  . TYR   A 1 573 ? 168.930 145.051 172.975 1.00 59.74  ? 599 TYR   A CG  1 
ATOM   4631 C CD1 . TYR   A 1 573 ? 169.404 145.568 171.781 1.00 62.35  ? 599 TYR   A CD1 1 
ATOM   4632 C CD2 . TYR   A 1 573 ? 169.077 143.694 173.200 1.00 64.85  ? 599 TYR   A CD2 1 
ATOM   4633 C CE1 . TYR   A 1 573 ? 169.993 144.755 170.837 1.00 60.30  ? 599 TYR   A CE1 1 
ATOM   4634 C CE2 . TYR   A 1 573 ? 169.663 142.875 172.261 1.00 65.49  ? 599 TYR   A CE2 1 
ATOM   4635 C CZ  . TYR   A 1 573 ? 170.119 143.411 171.081 1.00 62.57  ? 599 TYR   A CZ  1 
ATOM   4636 O OH  . TYR   A 1 573 ? 170.705 142.597 170.143 1.00 70.69  ? 599 TYR   A OH  1 
ATOM   4637 N N   . MET   A 1 574 ? 167.235 148.470 172.858 1.00 48.84  ? 600 MET   A N   1 
ATOM   4638 C CA  . MET   A 1 574 ? 167.005 149.610 171.983 1.00 49.63  ? 600 MET   A CA  1 
ATOM   4639 C C   . MET   A 1 574 ? 168.283 150.423 171.846 1.00 58.40  ? 600 MET   A C   1 
ATOM   4640 O O   . MET   A 1 574 ? 169.047 150.577 172.803 1.00 66.54  ? 600 MET   A O   1 
ATOM   4641 C CB  . MET   A 1 574 ? 165.878 150.501 172.520 1.00 55.58  ? 600 MET   A CB  1 
ATOM   4642 C CG  . MET   A 1 574 ? 166.130 151.053 173.915 1.00 64.70  ? 600 MET   A CG  1 
ATOM   4643 S SD  . MET   A 1 574 ? 164.687 151.868 174.622 1.00 90.90  ? 600 MET   A SD  1 
ATOM   4644 C CE  . MET   A 1 574 ? 164.598 153.342 173.615 1.00 74.79  ? 600 MET   A CE  1 
ATOM   4645 N N   . TYR   A 1 575 ? 168.500 150.940 170.640 1.00 59.12  ? 601 TYR   A N   1 
ATOM   4646 C CA  . TYR   A 1 575 ? 169.596 151.848 170.328 1.00 54.42  ? 601 TYR   A CA  1 
ATOM   4647 C C   . TYR   A 1 575 ? 169.029 153.245 170.140 1.00 54.26  ? 601 TYR   A C   1 
ATOM   4648 O O   . TYR   A 1 575 ? 168.132 153.439 169.316 1.00 62.85  ? 601 TYR   A O   1 
ATOM   4649 C CB  . TYR   A 1 575 ? 170.322 151.427 169.049 1.00 57.15  ? 601 TYR   A CB  1 
ATOM   4650 C CG  . TYR   A 1 575 ? 171.242 150.240 169.190 1.00 51.86  ? 601 TYR   A CG  1 
ATOM   4651 C CD1 . TYR   A 1 575 ? 172.549 150.402 169.615 1.00 55.41  ? 601 TYR   A CD1 1 
ATOM   4652 C CD2 . TYR   A 1 575 ? 170.811 148.964 168.876 1.00 46.51  ? 601 TYR   A CD2 1 
ATOM   4653 C CE1 . TYR   A 1 575 ? 173.392 149.330 169.738 1.00 54.52  ? 601 TYR   A CE1 1 
ATOM   4654 C CE2 . TYR   A 1 575 ? 171.649 147.886 168.997 1.00 51.20  ? 601 TYR   A CE2 1 
ATOM   4655 C CZ  . TYR   A 1 575 ? 172.939 148.075 169.427 1.00 58.22  ? 601 TYR   A CZ  1 
ATOM   4656 O OH  . TYR   A 1 575 ? 173.788 147.001 169.551 1.00 73.79  ? 601 TYR   A OH  1 
ATOM   4657 N N   . VAL   A 1 576 ? 169.558 154.210 170.888 1.00 52.92  ? 602 VAL   A N   1 
ATOM   4658 C CA  . VAL   A 1 576 ? 169.152 155.610 170.799 1.00 60.12  ? 602 VAL   A CA  1 
ATOM   4659 C C   . VAL   A 1 576 ? 170.375 156.408 170.374 1.00 63.72  ? 602 VAL   A C   1 
ATOM   4660 O O   . VAL   A 1 576 ? 171.426 156.327 171.023 1.00 72.57  ? 602 VAL   A O   1 
ATOM   4661 C CB  . VAL   A 1 576 ? 168.591 156.130 172.132 1.00 61.40  ? 602 VAL   A CB  1 
ATOM   4662 C CG1 . VAL   A 1 576 ? 168.106 157.564 171.983 1.00 62.29  ? 602 VAL   A CG1 1 
ATOM   4663 C CG2 . VAL   A 1 576 ? 167.467 155.225 172.629 1.00 65.96  ? 602 VAL   A CG2 1 
ATOM   4664 N N   . TYR   A 1 577 ? 170.245 157.172 169.288 1.00 57.98  ? 603 TYR   A N   1 
ATOM   4665 C CA  . TYR   A 1 577 ? 171.392 157.881 168.731 1.00 56.63  ? 603 TYR   A CA  1 
ATOM   4666 C C   . TYR   A 1 577 ? 170.957 159.216 168.149 1.00 63.26  ? 603 TYR   A C   1 
ATOM   4667 O O   . TYR   A 1 577 ? 169.786 159.427 167.833 1.00 74.03  ? 603 TYR   A O   1 
ATOM   4668 C CB  . TYR   A 1 577 ? 172.092 157.046 167.653 1.00 60.10  ? 603 TYR   A CB  1 
ATOM   4669 C CG  . TYR   A 1 577 ? 171.212 156.691 166.476 1.00 57.61  ? 603 TYR   A CG  1 
ATOM   4670 C CD1 . TYR   A 1 577 ? 170.414 155.560 166.499 1.00 59.81  ? 603 TYR   A CD1 1 
ATOM   4671 C CD2 . TYR   A 1 577 ? 171.192 157.480 165.335 1.00 65.51  ? 603 TYR   A CD2 1 
ATOM   4672 C CE1 . TYR   A 1 577 ? 169.614 155.230 165.426 1.00 67.83  ? 603 TYR   A CE1 1 
ATOM   4673 C CE2 . TYR   A 1 577 ? 170.394 157.157 164.259 1.00 67.08  ? 603 TYR   A CE2 1 
ATOM   4674 C CZ  . TYR   A 1 577 ? 169.608 156.032 164.309 1.00 69.42  ? 603 TYR   A CZ  1 
ATOM   4675 O OH  . TYR   A 1 577 ? 168.813 155.707 163.236 1.00 68.89  ? 603 TYR   A OH  1 
ATOM   4676 N N   . VAL   A 1 578 ? 171.927 160.120 168.017 1.00 60.68  ? 604 VAL   A N   1 
ATOM   4677 C CA  . VAL   A 1 578 ? 171.742 161.390 167.321 1.00 64.45  ? 604 VAL   A CA  1 
ATOM   4678 C C   . VAL   A 1 578 ? 172.944 161.612 166.416 1.00 64.59  ? 604 VAL   A C   1 
ATOM   4679 O O   . VAL   A 1 578 ? 174.090 161.433 166.842 1.00 70.44  ? 604 VAL   A O   1 
ATOM   4680 C CB  . VAL   A 1 578 ? 171.563 162.575 168.293 1.00 69.19  ? 604 VAL   A CB  1 
ATOM   4681 C CG1 . VAL   A 1 578 ? 172.769 162.734 169.219 1.00 72.02  ? 604 VAL   A CG1 1 
ATOM   4682 C CG2 . VAL   A 1 578 ? 171.309 163.860 167.517 1.00 72.13  ? 604 VAL   A CG2 1 
ATOM   4683 N N   . ASN   A 1 579 ? 172.687 161.994 165.168 1.00 67.89  ? 605 ASN   A N   1 
ATOM   4684 C CA  . ASN   A 1 579 ? 173.751 162.227 164.194 1.00 73.42  ? 605 ASN   A CA  1 
ATOM   4685 C C   . ASN   A 1 579 ? 174.416 163.553 164.537 1.00 80.73  ? 605 ASN   A C   1 
ATOM   4686 O O   . ASN   A 1 579 ? 173.892 164.625 164.229 1.00 92.97  ? 605 ASN   A O   1 
ATOM   4687 C CB  . ASN   A 1 579 ? 173.192 162.229 162.776 1.00 75.19  ? 605 ASN   A CB  1 
ATOM   4688 C CG  . ASN   A 1 579 ? 174.279 162.201 161.713 1.00 82.32  ? 605 ASN   A CG  1 
ATOM   4689 O OD1 . ASN   A 1 579 ? 175.432 162.547 161.971 1.00 83.73  ? 605 ASN   A OD1 1 
ATOM   4690 N ND2 . ASN   A 1 579 ? 173.912 161.790 160.506 1.00 83.32  ? 605 ASN   A ND2 1 
ATOM   4691 N N   . THR   A 1 580 ? 175.580 163.480 165.186 1.00 72.89  ? 606 THR   A N   1 
ATOM   4692 C CA  . THR   A 1 580 ? 176.268 164.694 165.611 1.00 73.03  ? 606 THR   A CA  1 
ATOM   4693 C C   . THR   A 1 580 ? 176.720 165.522 164.416 1.00 81.87  ? 606 THR   A C   1 
ATOM   4694 O O   . THR   A 1 580 ? 176.688 166.758 164.464 1.00 93.08  ? 606 THR   A O   1 
ATOM   4695 C CB  . THR   A 1 580 ? 177.460 164.339 166.496 1.00 73.65  ? 606 THR   A CB  1 
ATOM   4696 O OG1 . THR   A 1 580 ? 177.009 163.591 167.632 1.00 74.47  ? 606 THR   A OG1 1 
ATOM   4697 C CG2 . THR   A 1 580 ? 178.165 165.598 166.974 1.00 77.17  ? 606 THR   A CG2 1 
ATOM   4698 N N   . THR   A 1 581 ? 177.158 164.863 163.342 1.00 78.74  ? 607 THR   A N   1 
ATOM   4699 C CA  . THR   A 1 581 ? 177.569 165.595 162.148 1.00 88.70  ? 607 THR   A CA  1 
ATOM   4700 C C   . THR   A 1 581 ? 176.400 166.366 161.549 1.00 91.03  ? 607 THR   A C   1 
ATOM   4701 O O   . THR   A 1 581 ? 176.553 167.524 161.139 1.00 94.25  ? 607 THR   A O   1 
ATOM   4702 C CB  . THR   A 1 581 ? 178.158 164.630 161.120 1.00 92.21  ? 607 THR   A CB  1 
ATOM   4703 O OG1 . THR   A 1 581 ? 179.280 163.946 161.691 1.00 92.32  ? 607 THR   A OG1 1 
ATOM   4704 C CG2 . THR   A 1 581 ? 178.604 165.378 159.872 1.00 90.27  ? 607 THR   A CG2 1 
ATOM   4705 N N   . GLU   A 1 582 ? 175.223 165.738 161.489 1.00 91.62  ? 608 GLU   A N   1 
ATOM   4706 C CA  . GLU   A 1 582 ? 174.042 166.425 160.978 1.00 91.70  ? 608 GLU   A CA  1 
ATOM   4707 C C   . GLU   A 1 582 ? 173.677 167.612 161.855 1.00 90.06  ? 608 GLU   A C   1 
ATOM   4708 O O   . GLU   A 1 582 ? 173.311 168.677 161.348 1.00 99.77  ? 608 GLU   A O   1 
ATOM   4709 C CB  . GLU   A 1 582 ? 172.869 165.450 160.887 1.00 94.42  ? 608 GLU   A CB  1 
ATOM   4710 C CG  . GLU   A 1 582 ? 171.623 166.020 160.222 1.00 99.02  ? 608 GLU   A CG  1 
ATOM   4711 C CD  . GLU   A 1 582 ? 170.531 164.982 160.052 1.00 102.77 ? 608 GLU   A CD  1 
ATOM   4712 O OE1 . GLU   A 1 582 ? 170.750 163.816 160.442 1.00 101.67 ? 608 GLU   A OE1 1 
ATOM   4713 O OE2 . GLU   A 1 582 ? 169.452 165.332 159.528 1.00 106.06 ? 608 GLU   A OE2 1 
ATOM   4714 N N   . LEU   A 1 583 ? 173.766 167.447 163.177 1.00 88.04  ? 609 LEU   A N   1 
ATOM   4715 C CA  . LEU   A 1 583 ? 173.463 168.554 164.077 1.00 95.43  ? 609 LEU   A CA  1 
ATOM   4716 C C   . LEU   A 1 583 ? 174.440 169.706 163.882 1.00 104.94 ? 609 LEU   A C   1 
ATOM   4717 O O   . LEU   A 1 583 ? 174.035 170.875 163.858 1.00 114.65 ? 609 LEU   A O   1 
ATOM   4718 C CB  . LEU   A 1 583 ? 173.485 168.069 165.526 1.00 91.95  ? 609 LEU   A CB  1 
ATOM   4719 C CG  . LEU   A 1 583 ? 173.063 169.069 166.606 1.00 100.05 ? 609 LEU   A CG  1 
ATOM   4720 C CD1 . LEU   A 1 583 ? 171.610 169.482 166.440 1.00 101.44 ? 609 LEU   A CD1 1 
ATOM   4721 C CD2 . LEU   A 1 583 ? 173.293 168.471 167.984 1.00 101.72 ? 609 LEU   A CD2 1 
ATOM   4722 N N   . ALA   A 1 584 ? 175.733 169.399 163.745 1.00 98.42  ? 610 ALA   A N   1 
ATOM   4723 C CA  . ALA   A 1 584 ? 176.720 170.451 163.524 1.00 100.38 ? 610 ALA   A CA  1 
ATOM   4724 C C   . ALA   A 1 584 ? 176.475 171.171 162.204 1.00 103.28 ? 610 ALA   A C   1 
ATOM   4725 O O   . ALA   A 1 584 ? 176.553 172.405 162.136 1.00 110.47 ? 610 ALA   A O   1 
ATOM   4726 C CB  . ALA   A 1 584 ? 178.129 169.862 163.557 1.00 94.56  ? 610 ALA   A CB  1 
ATOM   4727 N N   . LEU   A 1 585 ? 176.180 170.417 161.143 1.00 103.33 ? 611 LEU   A N   1 
ATOM   4728 C CA  . LEU   A 1 585 ? 175.908 171.038 159.852 1.00 106.45 ? 611 LEU   A CA  1 
ATOM   4729 C C   . LEU   A 1 585 ? 174.669 171.919 159.922 1.00 109.95 ? 611 LEU   A C   1 
ATOM   4730 O O   . LEU   A 1 585 ? 174.649 173.021 159.363 1.00 119.12 ? 611 LEU   A O   1 
ATOM   4731 C CB  . LEU   A 1 585 ? 175.745 169.962 158.777 1.00 108.21 ? 611 LEU   A CB  1 
ATOM   4732 C CG  . LEU   A 1 585 ? 175.433 170.423 157.350 1.00 114.14 ? 611 LEU   A CG  1 
ATOM   4733 C CD1 . LEU   A 1 585 ? 176.502 171.370 156.824 1.00 117.44 ? 611 LEU   A CD1 1 
ATOM   4734 C CD2 . LEU   A 1 585 ? 175.291 169.217 156.435 1.00 113.34 ? 611 LEU   A CD2 1 
ATOM   4735 N N   . GLU   A 1 586 ? 173.627 171.453 160.614 1.00 109.67 ? 612 GLU   A N   1 
ATOM   4736 C CA  . GLU   A 1 586 ? 172.412 172.247 160.746 1.00 112.48 ? 612 GLU   A CA  1 
ATOM   4737 C C   . GLU   A 1 586 ? 172.673 173.522 161.536 1.00 116.37 ? 612 GLU   A C   1 
ATOM   4738 O O   . GLU   A 1 586 ? 172.165 174.591 161.182 1.00 127.77 ? 612 GLU   A O   1 
ATOM   4739 C CB  . GLU   A 1 586 ? 171.315 171.416 161.408 1.00 111.60 ? 612 GLU   A CB  1 
ATOM   4740 C CG  . GLU   A 1 586 ? 169.933 172.042 161.340 1.00 118.33 ? 612 GLU   A CG  1 
ATOM   4741 C CD  . GLU   A 1 586 ? 168.866 171.162 161.961 1.00 124.23 ? 612 GLU   A CD  1 
ATOM   4742 O OE1 . GLU   A 1 586 ? 169.206 170.058 162.435 1.00 126.38 ? 612 GLU   A OE1 1 
ATOM   4743 O OE2 . GLU   A 1 586 ? 167.688 171.576 161.976 1.00 122.69 ? 612 GLU   A OE2 1 
ATOM   4744 N N   . GLN   A 1 587 ? 173.461 173.432 162.610 1.00 110.74 ? 613 GLN   A N   1 
ATOM   4745 C CA  . GLN   A 1 587 ? 173.766 174.625 163.395 1.00 117.97 ? 613 GLN   A CA  1 
ATOM   4746 C C   . GLN   A 1 587 ? 174.573 175.630 162.583 1.00 125.64 ? 613 GLN   A C   1 
ATOM   4747 O O   . GLN   A 1 587 ? 174.302 176.836 162.627 1.00 130.09 ? 613 GLN   A O   1 
ATOM   4748 C CB  . GLN   A 1 587 ? 174.519 174.242 164.668 1.00 116.82 ? 613 GLN   A CB  1 
ATOM   4749 C CG  . GLN   A 1 587 ? 173.648 173.596 165.731 1.00 119.29 ? 613 GLN   A CG  1 
ATOM   4750 C CD  . GLN   A 1 587 ? 174.402 173.333 167.018 1.00 122.05 ? 613 GLN   A CD  1 
ATOM   4751 O OE1 . GLN   A 1 587 ? 175.558 173.730 167.166 1.00 125.79 ? 613 GLN   A OE1 1 
ATOM   4752 N NE2 . GLN   A 1 587 ? 173.750 172.659 167.958 1.00 119.16 ? 613 GLN   A NE2 1 
ATOM   4753 N N   . ASP   A 1 588 ? 175.568 175.153 161.831 1.00 129.41 ? 614 ASP   A N   1 
ATOM   4754 C CA  . ASP   A 1 588 ? 176.361 176.060 161.006 1.00 130.04 ? 614 ASP   A CA  1 
ATOM   4755 C C   . ASP   A 1 588 ? 175.507 176.699 159.918 1.00 130.37 ? 614 ASP   A C   1 
ATOM   4756 O O   . ASP   A 1 588 ? 175.641 177.897 159.634 1.00 139.56 ? 614 ASP   A O   1 
ATOM   4757 C CB  . ASP   A 1 588 ? 177.542 175.310 160.392 1.00 133.90 ? 614 ASP   A CB  1 
ATOM   4758 C CG  . ASP   A 1 588 ? 178.487 174.754 161.439 1.00 133.87 ? 614 ASP   A CG  1 
ATOM   4759 O OD1 . ASP   A 1 588 ? 178.226 174.952 162.644 1.00 131.31 ? 614 ASP   A OD1 1 
ATOM   4760 O OD2 . ASP   A 1 588 ? 179.491 174.117 161.056 1.00 133.92 ? 614 ASP   A OD2 1 
ATOM   4761 N N   . LEU   A 1 589 ? 174.621 175.916 159.298 1.00 128.63 ? 615 LEU   A N   1 
ATOM   4762 C CA  . LEU   A 1 589 ? 173.744 176.462 158.270 1.00 137.20 ? 615 LEU   A CA  1 
ATOM   4763 C C   . LEU   A 1 589 ? 172.796 177.497 158.858 1.00 139.06 ? 615 LEU   A C   1 
ATOM   4764 O O   . LEU   A 1 589 ? 172.540 178.536 158.240 1.00 147.05 ? 615 LEU   A O   1 
ATOM   4765 C CB  . LEU   A 1 589 ? 172.968 175.327 157.599 1.00 141.40 ? 615 LEU   A CB  1 
ATOM   4766 C CG  . LEU   A 1 589 ? 172.376 175.585 156.208 1.00 149.48 ? 615 LEU   A CG  1 
ATOM   4767 C CD1 . LEU   A 1 589 ? 172.154 174.259 155.490 1.00 147.18 ? 615 LEU   A CD1 1 
ATOM   4768 C CD2 . LEU   A 1 589 ? 171.074 176.382 156.271 1.00 149.18 ? 615 LEU   A CD2 1 
ATOM   4769 N N   . ALA   A 1 590 ? 172.266 177.231 160.053 1.00 133.80 ? 616 ALA   A N   1 
ATOM   4770 C CA  . ALA   A 1 590 ? 171.398 178.202 160.711 1.00 139.58 ? 616 ALA   A CA  1 
ATOM   4771 C C   . ALA   A 1 590 ? 172.152 179.485 161.029 1.00 146.46 ? 616 ALA   A C   1 
ATOM   4772 O O   . ALA   A 1 590 ? 171.614 180.585 160.867 1.00 151.89 ? 616 ALA   A O   1 
ATOM   4773 C CB  . ALA   A 1 590 ? 170.807 177.597 161.983 1.00 136.04 ? 616 ALA   A CB  1 
ATOM   4774 N N   . TYR   A 1 591 ? 173.399 179.365 161.493 1.00 150.23 ? 617 TYR   A N   1 
ATOM   4775 C CA  . TYR   A 1 591 ? 174.208 180.551 161.760 1.00 157.29 ? 617 TYR   A CA  1 
ATOM   4776 C C   . TYR   A 1 591 ? 174.435 181.361 160.489 1.00 155.90 ? 617 TYR   A C   1 
ATOM   4777 O O   . TYR   A 1 591 ? 174.313 182.594 160.494 1.00 157.91 ? 617 TYR   A O   1 
ATOM   4778 C CB  . TYR   A 1 591 ? 175.542 180.135 162.382 1.00 157.38 ? 617 TYR   A CB  1 
ATOM   4779 C CG  . TYR   A 1 591 ? 176.479 181.283 162.686 1.00 162.58 ? 617 TYR   A CG  1 
ATOM   4780 C CD1 . TYR   A 1 591 ? 176.357 182.013 163.861 1.00 163.87 ? 617 TYR   A CD1 1 
ATOM   4781 C CD2 . TYR   A 1 591 ? 177.494 181.630 161.804 1.00 162.51 ? 617 TYR   A CD2 1 
ATOM   4782 C CE1 . TYR   A 1 591 ? 177.214 183.060 164.145 1.00 165.98 ? 617 TYR   A CE1 1 
ATOM   4783 C CE2 . TYR   A 1 591 ? 178.356 182.674 162.079 1.00 165.85 ? 617 TYR   A CE2 1 
ATOM   4784 C CZ  . TYR   A 1 591 ? 178.212 183.385 163.251 1.00 168.28 ? 617 TYR   A CZ  1 
ATOM   4785 O OH  . TYR   A 1 591 ? 179.067 184.427 163.529 1.00 168.30 ? 617 TYR   A OH  1 
ATOM   4786 N N   . LEU   A 1 592 ? 174.768 180.684 159.387 1.00 151.87 ? 618 LEU   A N   1 
ATOM   4787 C CA  . LEU   A 1 592 ? 174.980 181.390 158.127 1.00 152.17 ? 618 LEU   A CA  1 
ATOM   4788 C C   . LEU   A 1 592 ? 173.699 182.066 157.653 1.00 155.65 ? 618 LEU   A C   1 
ATOM   4789 O O   . LEU   A 1 592 ? 173.733 183.199 157.160 1.00 161.94 ? 618 LEU   A O   1 
ATOM   4790 C CB  . LEU   A 1 592 ? 175.500 180.419 157.066 1.00 155.37 ? 618 LEU   A CB  1 
ATOM   4791 C CG  . LEU   A 1 592 ? 175.865 181.013 155.700 1.00 163.17 ? 618 LEU   A CG  1 
ATOM   4792 C CD1 . LEU   A 1 592 ? 176.959 182.063 155.835 1.00 165.22 ? 618 LEU   A CD1 1 
ATOM   4793 C CD2 . LEU   A 1 592 ? 176.297 179.920 154.735 1.00 165.18 ? 618 LEU   A CD2 1 
ATOM   4794 N N   . GLN   A 1 593 ? 172.561 181.382 157.786 1.00 155.83 ? 619 GLN   A N   1 
ATOM   4795 C CA  . GLN   A 1 593 ? 171.287 181.978 157.397 1.00 159.76 ? 619 GLN   A CA  1 
ATOM   4796 C C   . GLN   A 1 593 ? 170.968 183.192 158.258 1.00 161.43 ? 619 GLN   A C   1 
ATOM   4797 O O   . GLN   A 1 593 ? 170.445 184.195 157.761 1.00 165.70 ? 619 GLN   A O   1 
ATOM   4798 C CB  . GLN   A 1 593 ? 170.172 180.937 157.497 1.00 159.99 ? 619 GLN   A CB  1 
ATOM   4799 C CG  . GLN   A 1 593 ? 168.829 181.401 156.949 1.00 165.65 ? 619 GLN   A CG  1 
ATOM   4800 C CD  . GLN   A 1 593 ? 167.780 180.306 156.977 1.00 166.18 ? 619 GLN   A CD  1 
ATOM   4801 O OE1 . GLN   A 1 593 ? 168.066 179.166 157.343 1.00 165.84 ? 619 GLN   A OE1 1 
ATOM   4802 N NE2 . GLN   A 1 593 ? 166.557 180.647 156.589 1.00 163.17 ? 619 GLN   A NE2 1 
ATOM   4803 N N   . GLU   A 1 594 ? 171.265 183.114 159.556 1.00 160.77 ? 620 GLU   A N   1 
ATOM   4804 C CA  . GLU   A 1 594 ? 171.039 184.253 160.437 1.00 167.73 ? 620 GLU   A CA  1 
ATOM   4805 C C   . GLU   A 1 594 ? 171.900 185.438 160.024 1.00 171.43 ? 620 GLU   A C   1 
ATOM   4806 O O   . GLU   A 1 594 ? 171.428 186.581 160.003 1.00 174.28 ? 620 GLU   A O   1 
ATOM   4807 C CB  . GLU   A 1 594 ? 171.327 183.854 161.885 1.00 168.45 ? 620 GLU   A CB  1 
ATOM   4808 C CG  . GLU   A 1 594 ? 171.017 184.934 162.912 1.00 170.77 ? 620 GLU   A CG  1 
ATOM   4809 C CD  . GLU   A 1 594 ? 171.191 184.448 164.337 1.00 169.13 ? 620 GLU   A CD  1 
ATOM   4810 O OE1 . GLU   A 1 594 ? 171.623 183.291 164.523 1.00 163.99 ? 620 GLU   A OE1 1 
ATOM   4811 O OE2 . GLU   A 1 594 ? 170.895 185.222 165.272 1.00 169.76 ? 620 GLU   A OE2 1 
ATOM   4812 N N   . LEU   A 1 595 ? 173.168 185.185 159.694 1.00 172.77 ? 621 LEU   A N   1 
ATOM   4813 C CA  . LEU   A 1 595 ? 174.036 186.265 159.230 1.00 177.44 ? 621 LEU   A CA  1 
ATOM   4814 C C   . LEU   A 1 595 ? 173.521 186.867 157.928 1.00 179.51 ? 621 LEU   A C   1 
ATOM   4815 O O   . LEU   A 1 595 ? 173.530 188.093 157.753 1.00 182.47 ? 621 LEU   A O   1 
ATOM   4816 C CB  . LEU   A 1 595 ? 175.470 185.759 159.059 1.00 176.09 ? 621 LEU   A CB  1 
ATOM   4817 C CG  . LEU   A 1 595 ? 176.403 185.962 160.257 1.00 173.83 ? 621 LEU   A CG  1 
ATOM   4818 C CD1 . LEU   A 1 595 ? 175.936 185.194 161.489 1.00 171.07 ? 621 LEU   A CD1 1 
ATOM   4819 C CD2 . LEU   A 1 595 ? 177.825 185.562 159.889 1.00 172.16 ? 621 LEU   A CD2 1 
ATOM   4820 N N   . LYS   A 1 596 ? 173.073 186.019 156.998 1.00 176.89 ? 622 LYS   A N   1 
ATOM   4821 C CA  . LYS   A 1 596 ? 172.524 186.515 155.740 1.00 175.57 ? 622 LYS   A CA  1 
ATOM   4822 C C   . LYS   A 1 596 ? 171.292 187.379 155.979 1.00 178.02 ? 622 LYS   A C   1 
ATOM   4823 O O   . LYS   A 1 596 ? 171.140 188.441 155.366 1.00 182.11 ? 622 LYS   A O   1 
ATOM   4824 C CB  . LYS   A 1 596 ? 172.187 185.338 154.823 1.00 175.12 ? 622 LYS   A CB  1 
ATOM   4825 C CG  . LYS   A 1 596 ? 171.661 185.729 153.442 1.00 177.60 ? 622 LYS   A CG  1 
ATOM   4826 C CD  . LYS   A 1 596 ? 171.396 184.507 152.567 1.00 176.24 ? 622 LYS   A CD  1 
ATOM   4827 C CE  . LYS   A 1 596 ? 169.941 184.053 152.638 1.00 172.97 ? 622 LYS   A CE  1 
ATOM   4828 N NZ  . LYS   A 1 596 ? 169.513 183.660 154.009 1.00 170.06 ? 622 LYS   A NZ  1 
ATOM   4829 N N   . GLU   A 1 597 ? 170.400 186.938 156.869 1.00 177.22 ? 623 GLU   A N   1 
ATOM   4830 C CA  . GLU   A 1 597 ? 169.205 187.719 157.170 1.00 179.63 ? 623 GLU   A CA  1 
ATOM   4831 C C   . GLU   A 1 597 ? 169.566 189.044 157.828 1.00 182.18 ? 623 GLU   A C   1 
ATOM   4832 O O   . GLU   A 1 597 ? 168.965 190.081 157.523 1.00 184.76 ? 623 GLU   A O   1 
ATOM   4833 C CB  . GLU   A 1 597 ? 168.265 186.912 158.065 1.00 178.94 ? 623 GLU   A CB  1 
ATOM   4834 C CG  . GLU   A 1 597 ? 167.592 185.745 157.359 1.00 178.30 ? 623 GLU   A CG  1 
ATOM   4835 C CD  . GLU   A 1 597 ? 166.763 184.894 158.299 1.00 177.64 ? 623 GLU   A CD  1 
ATOM   4836 O OE1 . GLU   A 1 597 ? 166.683 185.234 159.498 1.00 179.24 ? 623 GLU   A OE1 1 
ATOM   4837 O OE2 . GLU   A 1 597 ? 166.191 183.883 157.840 1.00 175.34 ? 623 GLU   A OE2 1 
ATOM   4838 N N   . LYS   A 1 598 ? 170.543 189.029 158.738 1.00 182.46 ? 624 LYS   A N   1 
ATOM   4839 C CA  . LYS   A 1 598 ? 170.971 190.265 159.385 1.00 186.58 ? 624 LYS   A CA  1 
ATOM   4840 C C   . LYS   A 1 598 ? 171.551 191.244 158.372 1.00 189.57 ? 624 LYS   A C   1 
ATOM   4841 O O   . LYS   A 1 598 ? 171.299 192.452 158.451 1.00 191.80 ? 624 LYS   A O   1 
ATOM   4842 C CB  . LYS   A 1 598 ? 171.992 189.957 160.480 1.00 185.60 ? 624 LYS   A CB  1 
ATOM   4843 C CG  . LYS   A 1 598 ? 171.384 189.361 161.740 1.00 181.90 ? 624 LYS   A CG  1 
ATOM   4844 C CD  . LYS   A 1 598 ? 172.451 189.013 162.765 1.00 177.28 ? 624 LYS   A CD  1 
ATOM   4845 C CE  . LYS   A 1 598 ? 171.836 188.500 164.057 1.00 173.81 ? 624 LYS   A CE  1 
ATOM   4846 N NZ  . LYS   A 1 598 ? 172.869 188.060 165.034 1.00 171.19 ? 624 LYS   A NZ  1 
ATOM   4847 N N   . VAL   A 1 599 ? 172.338 190.745 157.419 1.00 189.92 ? 625 VAL   A N   1 
ATOM   4848 C CA  . VAL   A 1 599 ? 172.866 191.619 156.374 1.00 190.11 ? 625 VAL   A CA  1 
ATOM   4849 C C   . VAL   A 1 599 ? 171.730 192.160 155.513 1.00 187.48 ? 625 VAL   A C   1 
ATOM   4850 O O   . VAL   A 1 599 ? 171.723 193.339 155.139 1.00 183.77 ? 625 VAL   A O   1 
ATOM   4851 C CB  . VAL   A 1 599 ? 173.916 190.872 155.528 1.00 191.33 ? 625 VAL   A CB  1 
ATOM   4852 C CG1 . VAL   A 1 599 ? 174.293 191.684 154.293 1.00 189.38 ? 625 VAL   A CG1 1 
ATOM   4853 C CG2 . VAL   A 1 599 ? 175.157 190.575 156.361 1.00 190.02 ? 625 VAL   A CG2 1 
ATOM   4854 N N   . GLU   A 1 600 ? 170.756 191.309 155.182 1.00 189.70 ? 626 GLU   A N   1 
ATOM   4855 C CA  . GLU   A 1 600 ? 169.677 191.727 154.290 1.00 190.18 ? 626 GLU   A CA  1 
ATOM   4856 C C   . GLU   A 1 600 ? 168.789 192.787 154.932 1.00 191.53 ? 626 GLU   A C   1 
ATOM   4857 O O   . GLU   A 1 600 ? 168.418 193.768 154.277 1.00 191.23 ? 626 GLU   A O   1 
ATOM   4858 C CB  . GLU   A 1 600 ? 168.845 190.515 153.873 1.00 189.12 ? 626 GLU   A CB  1 
ATOM   4859 C CG  . GLU   A 1 600 ? 169.513 189.637 152.826 1.00 188.96 ? 626 GLU   A CG  1 
ATOM   4860 C CD  . GLU   A 1 600 ? 168.708 188.393 152.507 1.00 188.23 ? 626 GLU   A CD  1 
ATOM   4861 O OE1 . GLU   A 1 600 ? 167.600 188.241 153.061 1.00 186.86 ? 626 GLU   A OE1 1 
ATOM   4862 O OE2 . GLU   A 1 600 ? 169.185 187.566 151.701 1.00 188.75 ? 626 GLU   A OE2 1 
ATOM   4863 N N   . ASN   A 1 601 ? 168.438 192.617 156.208 1.00 191.67 ? 627 ASN   A N   1 
ATOM   4864 C CA  . ASN   A 1 601 ? 167.504 193.530 156.860 1.00 191.23 ? 627 ASN   A CA  1 
ATOM   4865 C C   . ASN   A 1 601 ? 168.137 194.854 157.282 1.00 193.52 ? 627 ASN   A C   1 
ATOM   4866 O O   . ASN   A 1 601 ? 167.458 195.659 157.930 1.00 193.41 ? 627 ASN   A O   1 
ATOM   4867 C CB  . ASN   A 1 601 ? 166.848 192.853 158.076 1.00 184.76 ? 627 ASN   A CB  1 
ATOM   4868 C CG  . ASN   A 1 601 ? 167.852 192.364 159.113 1.00 184.06 ? 627 ASN   A CG  1 
ATOM   4869 O OD1 . ASN   A 1 601 ? 168.867 193.005 159.379 1.00 185.68 ? 627 ASN   A OD1 1 
ATOM   4870 N ND2 . ASN   A 1 601 ? 167.558 191.215 159.711 1.00 183.88 ? 627 ASN   A ND2 1 
ATOM   4871 N N   . GLY   A 1 602 ? 169.405 195.100 156.942 1.00 194.06 ? 628 GLY   A N   1 
ATOM   4872 C CA  . GLY   A 1 602 ? 170.075 196.351 157.222 1.00 192.99 ? 628 GLY   A CA  1 
ATOM   4873 C C   . GLY   A 1 602 ? 171.068 196.297 158.364 1.00 195.80 ? 628 GLY   A C   1 
ATOM   4874 O O   . GLY   A 1 602 ? 171.935 197.175 158.451 1.00 199.29 ? 628 GLY   A O   1 
ATOM   4875 N N   . SER   A 1 603 ? 170.969 195.300 159.239 1.00 196.03 ? 629 SER   A N   1 
ATOM   4876 C CA  . SER   A 1 603 ? 171.951 195.148 160.299 1.00 200.34 ? 629 SER   A CA  1 
ATOM   4877 C C   . SER   A 1 603 ? 173.280 194.667 159.716 1.00 202.98 ? 629 SER   A C   1 
ATOM   4878 O O   . SER   A 1 603 ? 173.373 194.263 158.553 1.00 201.98 ? 629 SER   A O   1 
ATOM   4879 C CB  . SER   A 1 603 ? 171.443 194.178 161.366 1.00 196.86 ? 629 SER   A CB  1 
ATOM   4880 O OG  . SER   A 1 603 ? 171.088 192.928 160.803 1.00 194.86 ? 629 SER   A OG  1 
ATOM   4881 N N   . GLU   A 1 604 ? 174.321 194.713 160.549 1.00 204.96 ? 630 GLU   A N   1 
ATOM   4882 C CA  . GLU   A 1 604 ? 175.683 194.371 160.137 1.00 205.31 ? 630 GLU   A CA  1 
ATOM   4883 C C   . GLU   A 1 604 ? 176.127 195.260 158.973 1.00 207.07 ? 630 GLU   A C   1 
ATOM   4884 O O   . GLU   A 1 604 ? 176.401 194.799 157.862 1.00 206.40 ? 630 GLU   A O   1 
ATOM   4885 C CB  . GLU   A 1 604 ? 175.786 192.883 159.777 1.00 202.54 ? 630 GLU   A CB  1 
ATOM   4886 C CG  . GLU   A 1 604 ? 177.211 192.365 159.572 1.00 201.31 ? 630 GLU   A CG  1 
ATOM   4887 C CD  . GLU   A 1 604 ? 178.043 192.393 160.841 1.00 198.19 ? 630 GLU   A CD  1 
ATOM   4888 O OE1 . GLU   A 1 604 ? 177.463 192.561 161.934 1.00 199.57 ? 630 GLU   A OE1 1 
ATOM   4889 O OE2 . GLU   A 1 604 ? 179.280 192.249 160.744 1.00 190.32 ? 630 GLU   A OE2 1 
ATOM   4890 N N   . THR   A 1 605 ? 176.181 196.565 159.252 1.00 208.51 ? 631 THR   A N   1 
ATOM   4891 C CA  . THR   A 1 605 ? 176.529 197.544 158.227 1.00 208.55 ? 631 THR   A CA  1 
ATOM   4892 C C   . THR   A 1 605 ? 177.947 197.367 157.698 1.00 210.35 ? 631 THR   A C   1 
ATOM   4893 O O   . THR   A 1 605 ? 178.245 197.845 156.597 1.00 212.26 ? 631 THR   A O   1 
ATOM   4894 C CB  . THR   A 1 605 ? 176.365 198.962 158.779 1.00 206.33 ? 631 THR   A CB  1 
ATOM   4895 O OG1 . THR   A 1 605 ? 177.198 199.129 159.934 1.00 206.53 ? 631 THR   A OG1 1 
ATOM   4896 C CG2 . THR   A 1 605 ? 174.914 199.226 159.159 1.00 203.40 ? 631 THR   A CG2 1 
ATOM   4897 N N   . GLY   A 1 606 ? 178.825 196.702 158.446 1.00 209.22 ? 632 GLY   A N   1 
ATOM   4898 C CA  . GLY   A 1 606 ? 180.194 196.515 158.029 1.00 209.56 ? 632 GLY   A CA  1 
ATOM   4899 C C   . GLY   A 1 606 ? 180.296 195.692 156.760 1.00 213.02 ? 632 GLY   A C   1 
ATOM   4900 O O   . GLY   A 1 606 ? 179.327 195.057 156.332 1.00 212.60 ? 632 GLY   A O   1 
ATOM   4901 N N   . PRO   A 1 607 ? 181.469 195.697 156.122 1.00 215.00 ? 633 PRO   A N   1 
ATOM   4902 C CA  . PRO   A 1 607 ? 181.615 194.971 154.854 1.00 212.44 ? 633 PRO   A CA  1 
ATOM   4903 C C   . PRO   A 1 607 ? 181.408 193.475 155.034 1.00 211.35 ? 633 PRO   A C   1 
ATOM   4904 O O   . PRO   A 1 607 ? 181.818 192.885 156.035 1.00 212.25 ? 633 PRO   A O   1 
ATOM   4905 C CB  . PRO   A 1 607 ? 183.050 195.296 154.422 1.00 210.63 ? 633 PRO   A CB  1 
ATOM   4906 C CG  . PRO   A 1 607 ? 183.762 195.614 155.686 1.00 210.21 ? 633 PRO   A CG  1 
ATOM   4907 C CD  . PRO   A 1 607 ? 182.749 196.269 156.579 1.00 212.39 ? 633 PRO   A CD  1 
ATOM   4908 N N   . LEU   A 1 608 ? 180.764 192.865 154.045 1.00 208.50 ? 634 LEU   A N   1 
ATOM   4909 C CA  . LEU   A 1 608 ? 180.493 191.440 154.103 1.00 206.60 ? 634 LEU   A CA  1 
ATOM   4910 C C   . LEU   A 1 608 ? 181.796 190.647 153.950 1.00 206.02 ? 634 LEU   A C   1 
ATOM   4911 O O   . LEU   A 1 608 ? 182.745 191.123 153.321 1.00 205.08 ? 634 LEU   A O   1 
ATOM   4912 C CB  . LEU   A 1 608 ? 179.499 191.036 153.014 1.00 204.83 ? 634 LEU   A CB  1 
ATOM   4913 C CG  . LEU   A 1 608 ? 179.950 190.903 151.550 1.00 204.53 ? 634 LEU   A CG  1 
ATOM   4914 C CD1 . LEU   A 1 608 ? 178.762 190.478 150.693 1.00 202.71 ? 634 LEU   A CD1 1 
ATOM   4915 C CD2 . LEU   A 1 608 ? 180.573 192.181 150.997 1.00 204.20 ? 634 LEU   A CD2 1 
ATOM   4916 N N   . PRO   A 1 609 ? 181.879 189.443 154.522 1.00 205.03 ? 635 PRO   A N   1 
ATOM   4917 C CA  . PRO   A 1 609 ? 183.064 188.621 154.294 1.00 204.41 ? 635 PRO   A CA  1 
ATOM   4918 C C   . PRO   A 1 609 ? 183.180 188.243 152.832 1.00 203.25 ? 635 PRO   A C   1 
ATOM   4919 O O   . PRO   A 1 609 ? 182.170 188.203 152.103 1.00 202.42 ? 635 PRO   A O   1 
ATOM   4920 C CB  . PRO   A 1 609 ? 182.817 187.388 155.176 1.00 202.50 ? 635 PRO   A CB  1 
ATOM   4921 C CG  . PRO   A 1 609 ? 181.863 187.825 156.196 1.00 200.35 ? 635 PRO   A CG  1 
ATOM   4922 C CD  . PRO   A 1 609 ? 180.989 188.830 155.528 1.00 201.60 ? 635 PRO   A CD  1 
ATOM   4923 N N   . PRO   A 1 610 ? 184.401 187.976 152.345 1.00 202.73 ? 636 PRO   A N   1 
ATOM   4924 C CA  . PRO   A 1 610 ? 184.533 187.546 150.941 1.00 201.94 ? 636 PRO   A CA  1 
ATOM   4925 C C   . PRO   A 1 610 ? 183.778 186.265 150.630 1.00 202.02 ? 636 PRO   A C   1 
ATOM   4926 O O   . PRO   A 1 610 ? 183.232 186.121 149.530 1.00 201.69 ? 636 PRO   A O   1 
ATOM   4927 C CB  . PRO   A 1 610 ? 186.048 187.372 150.771 1.00 201.53 ? 636 PRO   A CB  1 
ATOM   4928 C CG  . PRO   A 1 610 ? 186.549 187.087 152.134 1.00 201.57 ? 636 PRO   A CG  1 
ATOM   4929 C CD  . PRO   A 1 610 ? 185.688 187.892 153.059 1.00 201.70 ? 636 PRO   A CD  1 
ATOM   4930 N N   . GLU   A 1 611 ? 183.735 185.323 151.576 1.00 202.90 ? 637 GLU   A N   1 
ATOM   4931 C CA  . GLU   A 1 611 ? 182.998 184.084 151.353 1.00 201.43 ? 637 GLU   A CA  1 
ATOM   4932 C C   . GLU   A 1 611 ? 181.495 184.327 151.299 1.00 201.23 ? 637 GLU   A C   1 
ATOM   4933 O O   . GLU   A 1 611 ? 180.769 183.566 150.649 1.00 199.33 ? 637 GLU   A O   1 
ATOM   4934 C CB  . GLU   A 1 611 ? 183.327 183.069 152.450 1.00 197.84 ? 637 GLU   A CB  1 
ATOM   4935 C CG  . GLU   A 1 611 ? 184.768 182.576 152.440 1.00 196.16 ? 637 GLU   A CG  1 
ATOM   4936 C CD  . GLU   A 1 611 ? 185.090 181.707 151.237 1.00 194.14 ? 637 GLU   A CD  1 
ATOM   4937 O OE1 . GLU   A 1 611 ? 184.155 181.335 150.497 1.00 192.95 ? 637 GLU   A OE1 1 
ATOM   4938 O OE2 . GLU   A 1 611 ? 186.282 181.395 151.032 1.00 192.87 ? 637 GLU   A OE2 1 
ATOM   4939 N N   . LEU   A 1 612 ? 181.009 185.361 151.988 1.00 201.88 ? 638 LEU   A N   1 
ATOM   4940 C CA  . LEU   A 1 612 ? 179.590 185.694 151.937 1.00 201.48 ? 638 LEU   A CA  1 
ATOM   4941 C C   . LEU   A 1 612 ? 179.194 186.344 150.615 1.00 203.36 ? 638 LEU   A C   1 
ATOM   4942 O O   . LEU   A 1 612 ? 178.003 186.361 150.285 1.00 202.77 ? 638 LEU   A O   1 
ATOM   4943 C CB  . LEU   A 1 612 ? 179.231 186.612 153.108 1.00 200.63 ? 638 LEU   A CB  1 
ATOM   4944 C CG  . LEU   A 1 612 ? 177.756 186.659 153.522 1.00 198.87 ? 638 LEU   A CG  1 
ATOM   4945 C CD1 . LEU   A 1 612 ? 177.627 186.625 155.038 1.00 193.12 ? 638 LEU   A CD1 1 
ATOM   4946 C CD2 . LEU   A 1 612 ? 177.069 187.895 152.965 1.00 199.38 ? 638 LEU   A CD2 1 
ATOM   4947 N N   . GLN   A 1 613 ? 180.155 186.879 149.858 1.00 205.47 ? 639 GLN   A N   1 
ATOM   4948 C CA  . GLN   A 1 613 ? 179.827 187.536 148.593 1.00 206.55 ? 639 GLN   A CA  1 
ATOM   4949 C C   . GLN   A 1 613 ? 179.171 186.591 147.591 1.00 206.75 ? 639 GLN   A C   1 
ATOM   4950 O O   . GLN   A 1 613 ? 178.183 186.998 146.953 1.00 206.36 ? 639 GLN   A O   1 
ATOM   4951 C CB  . GLN   A 1 613 ? 181.089 188.190 148.014 1.00 205.92 ? 639 GLN   A CB  1 
ATOM   4952 C CG  . GLN   A 1 613 ? 181.569 189.407 148.782 1.00 205.59 ? 639 GLN   A CG  1 
ATOM   4953 C CD  . GLN   A 1 613 ? 182.894 189.934 148.267 1.00 203.42 ? 639 GLN   A CD  1 
ATOM   4954 O OE1 . GLN   A 1 613 ? 183.296 189.644 147.140 1.00 202.42 ? 639 GLN   A OE1 1 
ATOM   4955 N NE2 . GLN   A 1 613 ? 183.583 190.710 149.096 1.00 201.77 ? 639 GLN   A NE2 1 
ATOM   4956 N N   . PRO   A 1 614 ? 179.655 185.359 147.383 1.00 206.79 ? 640 PRO   A N   1 
ATOM   4957 C CA  . PRO   A 1 614 ? 178.911 184.424 146.522 1.00 205.15 ? 640 PRO   A CA  1 
ATOM   4958 C C   . PRO   A 1 614 ? 177.481 184.177 146.965 1.00 203.84 ? 640 PRO   A C   1 
ATOM   4959 O O   . PRO   A 1 614 ? 176.608 183.983 146.109 1.00 205.75 ? 640 PRO   A O   1 
ATOM   4960 C CB  . PRO   A 1 614 ? 179.742 183.138 146.611 1.00 202.12 ? 640 PRO   A CB  1 
ATOM   4961 C CG  . PRO   A 1 614 ? 181.114 183.592 146.859 1.00 202.36 ? 640 PRO   A CG  1 
ATOM   4962 C CD  . PRO   A 1 614 ? 181.040 184.901 147.601 1.00 203.76 ? 640 PRO   A CD  1 
ATOM   4963 N N   . LEU   A 1 615 ? 177.212 184.164 148.272 1.00 201.93 ? 641 LEU   A N   1 
ATOM   4964 C CA  . LEU   A 1 615 ? 175.861 183.879 148.744 1.00 200.74 ? 641 LEU   A CA  1 
ATOM   4965 C C   . LEU   A 1 615 ? 174.883 184.960 148.301 1.00 205.38 ? 641 LEU   A C   1 
ATOM   4966 O O   . LEU   A 1 615 ? 173.811 184.661 147.761 1.00 204.07 ? 641 LEU   A O   1 
ATOM   4967 C CB  . LEU   A 1 615 ? 175.859 183.740 150.267 1.00 197.83 ? 641 LEU   A CB  1 
ATOM   4968 C CG  . LEU   A 1 615 ? 176.573 182.503 150.822 1.00 192.20 ? 641 LEU   A CG  1 
ATOM   4969 C CD1 . LEU   A 1 615 ? 176.803 182.639 152.317 1.00 188.96 ? 641 LEU   A CD1 1 
ATOM   4970 C CD2 . LEU   A 1 615 ? 175.778 181.239 150.525 1.00 186.72 ? 641 LEU   A CD2 1 
ATOM   4971 N N   . LEU   A 1 616 ? 175.233 186.229 148.521 1.00 206.40 ? 642 LEU   A N   1 
ATOM   4972 C CA  . LEU   A 1 616 ? 174.367 187.312 148.068 1.00 205.68 ? 642 LEU   A CA  1 
ATOM   4973 C C   . LEU   A 1 616 ? 174.321 187.380 146.547 1.00 207.48 ? 642 LEU   A C   1 
ATOM   4974 O O   . LEU   A 1 616 ? 173.248 187.574 145.963 1.00 206.05 ? 642 LEU   A O   1 
ATOM   4975 C CB  . LEU   A 1 616 ? 174.834 188.647 148.652 1.00 203.23 ? 642 LEU   A CB  1 
ATOM   4976 C CG  . LEU   A 1 616 ? 174.888 188.768 150.180 1.00 201.59 ? 642 LEU   A CG  1 
ATOM   4977 C CD1 . LEU   A 1 616 ? 175.283 190.181 150.577 1.00 199.65 ? 642 LEU   A CD1 1 
ATOM   4978 C CD2 . LEU   A 1 616 ? 173.563 188.390 150.832 1.00 197.65 ? 642 LEU   A CD2 1 
ATOM   4979 N N   . GLU   A 1 617 ? 175.473 187.232 145.887 1.00 209.38 ? 643 GLU   A N   1 
ATOM   4980 C CA  . GLU   A 1 617 ? 175.485 187.217 144.428 1.00 208.05 ? 643 GLU   A CA  1 
ATOM   4981 C C   . GLU   A 1 617 ? 174.705 186.027 143.882 1.00 209.15 ? 643 GLU   A C   1 
ATOM   4982 O O   . GLU   A 1 617 ? 173.967 186.159 142.898 1.00 206.60 ? 643 GLU   A O   1 
ATOM   4983 C CB  . GLU   A 1 617 ? 176.925 187.193 143.915 1.00 205.68 ? 643 GLU   A CB  1 
ATOM   4984 C CG  . GLU   A 1 617 ? 177.690 188.483 144.155 1.00 202.81 ? 643 GLU   A CG  1 
ATOM   4985 C CD  . GLU   A 1 617 ? 179.120 188.413 143.655 1.00 199.38 ? 643 GLU   A CD  1 
ATOM   4986 O OE1 . GLU   A 1 617 ? 179.498 187.373 143.076 1.00 199.52 ? 643 GLU   A OE1 1 
ATOM   4987 O OE2 . GLU   A 1 617 ? 179.866 189.397 143.842 1.00 195.89 ? 643 GLU   A OE2 1 
ATOM   4988 N N   . GLY   A 1 618 ? 174.855 184.861 144.507 1.00 211.70 ? 644 GLY   A N   1 
ATOM   4989 C CA  . GLY   A 1 618 ? 174.184 183.656 144.070 1.00 208.68 ? 644 GLY   A CA  1 
ATOM   4990 C C   . GLY   A 1 618 ? 174.850 182.926 142.924 1.00 209.78 ? 644 GLY   A C   1 
ATOM   4991 O O   . GLY   A 1 618 ? 174.363 181.858 142.531 1.00 207.77 ? 644 GLY   A O   1 
ATOM   4992 N N   . GLU   A 1 619 ? 175.939 183.463 142.372 1.00 214.06 ? 645 GLU   A N   1 
ATOM   4993 C CA  . GLU   A 1 619 ? 176.670 182.823 141.287 1.00 213.35 ? 645 GLU   A CA  1 
ATOM   4994 C C   . GLU   A 1 619 ? 178.159 183.042 141.503 1.00 212.07 ? 645 GLU   A C   1 
ATOM   4995 O O   . GLU   A 1 619 ? 178.596 184.180 141.700 1.00 210.15 ? 645 GLU   A O   1 
ATOM   4996 C CB  . GLU   A 1 619 ? 176.246 183.383 139.923 1.00 212.72 ? 645 GLU   A CB  1 
ATOM   4997 C CG  . GLU   A 1 619 ? 174.773 183.189 139.599 1.00 211.67 ? 645 GLU   A CG  1 
ATOM   4998 C CD  . GLU   A 1 619 ? 174.392 183.763 138.249 1.00 209.58 ? 645 GLU   A CD  1 
ATOM   4999 O OE1 . GLU   A 1 619 ? 175.247 184.418 137.617 1.00 208.57 ? 645 GLU   A OE1 1 
ATOM   5000 O OE2 . GLU   A 1 619 ? 173.236 183.560 137.820 1.00 208.38 ? 645 GLU   A OE2 1 
ATOM   5001 N N   . VAL   A 1 620 ? 178.929 181.956 141.464 1.00 212.31 ? 646 VAL   A N   1 
ATOM   5002 C CA  . VAL   A 1 620 ? 180.382 182.020 141.640 1.00 212.49 ? 646 VAL   A CA  1 
ATOM   5003 C C   . VAL   A 1 620 ? 180.977 182.162 140.242 1.00 213.23 ? 646 VAL   A C   1 
ATOM   5004 O O   . VAL   A 1 620 ? 181.280 181.179 139.565 1.00 211.89 ? 646 VAL   A O   1 
ATOM   5005 C CB  . VAL   A 1 620 ? 180.925 180.802 142.385 1.00 209.45 ? 646 VAL   A CB  1 
ATOM   5006 C CG1 . VAL   A 1 620 ? 182.343 181.074 142.888 1.00 207.95 ? 646 VAL   A CG1 1 
ATOM   5007 C CG2 . VAL   A 1 620 ? 180.000 180.430 143.535 1.00 205.44 ? 646 VAL   A CG2 1 
ATOM   5008 N N   . LYS   A 1 621 ? 181.138 183.411 139.806 1.00 214.56 ? 647 LYS   A N   1 
ATOM   5009 C CA  . LYS   A 1 621 ? 181.722 183.736 138.511 1.00 214.00 ? 647 LYS   A CA  1 
ATOM   5010 C C   . LYS   A 1 621 ? 182.836 184.750 138.719 1.00 215.92 ? 647 LYS   A C   1 
ATOM   5011 O O   . LYS   A 1 621 ? 182.638 185.764 139.396 1.00 215.48 ? 647 LYS   A O   1 
ATOM   5012 C CB  . LYS   A 1 621 ? 180.664 184.289 137.550 1.00 210.97 ? 647 LYS   A CB  1 
ATOM   5013 C CG  . LYS   A 1 621 ? 179.531 183.315 137.261 1.00 210.09 ? 647 LYS   A CG  1 
ATOM   5014 C CD  . LYS   A 1 621 ? 178.487 183.923 136.340 1.00 208.07 ? 647 LYS   A CD  1 
ATOM   5015 C CE  . LYS   A 1 621 ? 177.373 182.932 136.039 1.00 206.57 ? 647 LYS   A CE  1 
ATOM   5016 N NZ  . LYS   A 1 621 ? 176.314 183.521 135.174 1.00 205.10 ? 647 LYS   A NZ  1 
ATOM   5017 N N   . GLY   A 1 622 ? 183.999 184.475 138.136 1.00 217.61 ? 648 GLY   A N   1 
ATOM   5018 C CA  . GLY   A 1 622 ? 185.146 185.351 138.316 1.00 216.72 ? 648 GLY   A CA  1 
ATOM   5019 C C   . GLY   A 1 622 ? 185.619 185.438 139.750 1.00 216.51 ? 648 GLY   A C   1 
ATOM   5020 O O   . GLY   A 1 622 ? 185.905 186.537 140.242 1.00 215.17 ? 648 GLY   A O   1 
ATOM   5021 N N   . GLY   A 1 623 ? 185.709 184.301 140.436 1.00 216.86 ? 649 GLY   A N   1 
ATOM   5022 C CA  . GLY   A 1 623 ? 186.141 184.275 141.813 1.00 216.10 ? 649 GLY   A CA  1 
ATOM   5023 C C   . GLY   A 1 623 ? 186.505 182.879 142.277 1.00 215.41 ? 649 GLY   A C   1 
ATOM   5024 O O   . GLY   A 1 623 ? 186.354 181.897 141.543 1.00 213.73 ? 649 GLY   A O   1 
ATOM   5025 N N   . PRO   A 1 624 ? 187.001 182.763 143.511 1.00 216.03 ? 650 PRO   A N   1 
ATOM   5026 C CA  . PRO   A 1 624 ? 187.363 181.441 144.034 1.00 213.05 ? 650 PRO   A CA  1 
ATOM   5027 C C   . PRO   A 1 624 ? 186.142 180.547 144.187 1.00 210.13 ? 650 PRO   A C   1 
ATOM   5028 O O   . PRO   A 1 624 ? 185.021 181.019 144.392 1.00 209.85 ? 650 PRO   A O   1 
ATOM   5029 C CB  . PRO   A 1 624 ? 188.005 181.757 145.390 1.00 209.97 ? 650 PRO   A CB  1 
ATOM   5030 C CG  . PRO   A 1 624 ? 187.429 183.069 145.785 1.00 210.62 ? 650 PRO   A CG  1 
ATOM   5031 C CD  . PRO   A 1 624 ? 187.208 183.828 144.509 1.00 213.11 ? 650 PRO   A CD  1 
ATOM   5032 N N   . GLU   A 1 625 ? 186.372 179.243 144.072 1.00 205.90 ? 651 GLU   A N   1 
ATOM   5033 C CA  . GLU   A 1 625 ? 185.279 178.288 144.163 1.00 201.75 ? 651 GLU   A CA  1 
ATOM   5034 C C   . GLU   A 1 625 ? 184.650 178.342 145.556 1.00 201.69 ? 651 GLU   A C   1 
ATOM   5035 O O   . GLU   A 1 625 ? 185.363 178.539 146.549 1.00 199.96 ? 651 GLU   A O   1 
ATOM   5036 C CB  . GLU   A 1 625 ? 185.775 176.872 143.867 1.00 198.73 ? 651 GLU   A CB  1 
ATOM   5037 C CG  . GLU   A 1 625 ? 186.328 176.689 142.465 1.00 196.58 ? 651 GLU   A CG  1 
ATOM   5038 C CD  . GLU   A 1 625 ? 186.762 175.263 142.193 1.00 191.98 ? 651 GLU   A CD  1 
ATOM   5039 O OE1 . GLU   A 1 625 ? 186.628 174.416 143.101 1.00 192.04 ? 651 GLU   A OE1 1 
ATOM   5040 O OE2 . GLU   A 1 625 ? 187.238 174.988 141.071 1.00 186.23 ? 651 GLU   A OE2 1 
ATOM   5041 N N   . PRO   A 1 626 ? 183.331 178.177 145.675 1.00 200.15 ? 652 PRO   A N   1 
ATOM   5042 C CA  . PRO   A 1 626 ? 182.698 178.304 146.991 1.00 194.58 ? 652 PRO   A CA  1 
ATOM   5043 C C   . PRO   A 1 626 ? 183.069 177.153 147.911 1.00 187.71 ? 652 PRO   A C   1 
ATOM   5044 O O   . PRO   A 1 626 ? 183.385 176.045 147.469 1.00 187.56 ? 652 PRO   A O   1 
ATOM   5045 C CB  . PRO   A 1 626 ? 181.203 178.292 146.663 1.00 192.41 ? 652 PRO   A CB  1 
ATOM   5046 C CG  . PRO   A 1 626 ? 181.112 177.444 145.454 1.00 192.92 ? 652 PRO   A CG  1 
ATOM   5047 C CD  . PRO   A 1 626 ? 182.373 177.687 144.665 1.00 197.11 ? 652 PRO   A CD  1 
ATOM   5048 N N   . THR   A 1 627 ? 183.024 177.429 149.212 1.00 182.24 ? 653 THR   A N   1 
ATOM   5049 C CA  . THR   A 1 627 ? 183.257 176.393 150.198 1.00 177.68 ? 653 THR   A CA  1 
ATOM   5050 C C   . THR   A 1 627 ? 182.110 175.383 150.166 1.00 174.72 ? 653 THR   A C   1 
ATOM   5051 O O   . THR   A 1 627 ? 181.037 175.674 149.632 1.00 174.12 ? 653 THR   A O   1 
ATOM   5052 C CB  . THR   A 1 627 ? 183.381 176.993 151.597 1.00 175.09 ? 653 THR   A CB  1 
ATOM   5053 O OG1 . THR   A 1 627 ? 182.141 177.607 151.970 1.00 173.27 ? 653 THR   A OG1 1 
ATOM   5054 C CG2 . THR   A 1 627 ? 184.496 178.030 151.644 1.00 176.29 ? 653 THR   A CG2 1 
ATOM   5055 N N   . PRO   A 1 628 ? 182.318 174.176 150.708 1.00 171.69 ? 654 PRO   A N   1 
ATOM   5056 C CA  . PRO   A 1 628 ? 181.212 173.201 150.744 1.00 170.22 ? 654 PRO   A CA  1 
ATOM   5057 C C   . PRO   A 1 628 ? 179.982 173.705 151.478 1.00 169.76 ? 654 PRO   A C   1 
ATOM   5058 O O   . PRO   A 1 628 ? 178.858 173.356 151.096 1.00 168.31 ? 654 PRO   A O   1 
ATOM   5059 C CB  . PRO   A 1 628 ? 181.833 171.992 151.457 1.00 167.01 ? 654 PRO   A CB  1 
ATOM   5060 C CG  . PRO   A 1 628 ? 183.289 172.127 151.246 1.00 166.58 ? 654 PRO   A CG  1 
ATOM   5061 C CD  . PRO   A 1 628 ? 183.569 173.596 151.231 1.00 170.98 ? 654 PRO   A CD  1 
ATOM   5062 N N   . LEU   A 1 629 ? 180.161 174.514 152.524 1.00 167.82 ? 655 LEU   A N   1 
ATOM   5063 C CA  . LEU   A 1 629 ? 179.013 175.073 153.232 1.00 167.09 ? 655 LEU   A CA  1 
ATOM   5064 C C   . LEU   A 1 629 ? 178.203 175.988 152.320 1.00 167.40 ? 655 LEU   A C   1 
ATOM   5065 O O   . LEU   A 1 629 ? 176.966 175.945 152.321 1.00 165.61 ? 655 LEU   A O   1 
ATOM   5066 C CB  . LEU   A 1 629 ? 179.487 175.828 154.475 1.00 167.06 ? 655 LEU   A CB  1 
ATOM   5067 C CG  . LEU   A 1 629 ? 178.554 175.840 155.689 1.00 165.32 ? 655 LEU   A CG  1 
ATOM   5068 C CD1 . LEU   A 1 629 ? 179.256 176.487 156.874 1.00 157.99 ? 655 LEU   A CD1 1 
ATOM   5069 C CD2 . LEU   A 1 629 ? 177.245 176.553 155.385 1.00 163.64 ? 655 LEU   A CD2 1 
ATOM   5070 N N   . VAL   A 1 630 ? 178.885 176.822 151.533 1.00 168.52 ? 656 VAL   A N   1 
ATOM   5071 C CA  . VAL   A 1 630 ? 178.190 177.711 150.608 1.00 172.48 ? 656 VAL   A CA  1 
ATOM   5072 C C   . VAL   A 1 630 ? 177.456 176.902 149.548 1.00 173.58 ? 656 VAL   A C   1 
ATOM   5073 O O   . VAL   A 1 630 ? 176.321 177.225 149.172 1.00 173.27 ? 656 VAL   A O   1 
ATOM   5074 C CB  . VAL   A 1 630 ? 179.187 178.704 149.979 1.00 176.62 ? 656 VAL   A CB  1 
ATOM   5075 C CG1 . VAL   A 1 630 ? 178.533 179.481 148.842 1.00 180.06 ? 656 VAL   A CG1 1 
ATOM   5076 C CG2 . VAL   A 1 630 ? 179.725 179.660 151.037 1.00 176.56 ? 656 VAL   A CG2 1 
ATOM   5077 N N   . GLN   A 1 631 ? 178.094 175.842 149.043 1.00 173.11 ? 657 GLN   A N   1 
ATOM   5078 C CA  . GLN   A 1 631 ? 177.437 174.979 148.067 1.00 173.49 ? 657 GLN   A CA  1 
ATOM   5079 C C   . GLN   A 1 631 ? 176.187 174.344 148.655 1.00 169.35 ? 657 GLN   A C   1 
ATOM   5080 O O   . GLN   A 1 631 ? 175.142 174.287 147.996 1.00 167.94 ? 657 GLN   A O   1 
ATOM   5081 C CB  . GLN   A 1 631 ? 178.403 173.895 147.589 1.00 173.50 ? 657 GLN   A CB  1 
ATOM   5082 C CG  . GLN   A 1 631 ? 179.608 174.416 146.831 1.00 176.28 ? 657 GLN   A CG  1 
ATOM   5083 C CD  . GLN   A 1 631 ? 180.587 173.316 146.472 1.00 176.28 ? 657 GLN   A CD  1 
ATOM   5084 O OE1 . GLN   A 1 631 ? 180.275 172.131 146.586 1.00 174.66 ? 657 GLN   A OE1 1 
ATOM   5085 N NE2 . GLN   A 1 631 ? 181.781 173.704 146.039 1.00 178.54 ? 657 GLN   A NE2 1 
ATOM   5086 N N   . THR   A 1 632 ? 176.274 173.863 149.896 1.00 165.30 ? 658 THR   A N   1 
ATOM   5087 C CA  . THR   A 1 632 ? 175.113 173.254 150.536 1.00 165.56 ? 658 THR   A CA  1 
ATOM   5088 C C   . THR   A 1 632 ? 173.994 174.269 150.723 1.00 164.25 ? 658 THR   A C   1 
ATOM   5089 O O   . THR   A 1 632 ? 172.819 173.955 150.502 1.00 163.15 ? 658 THR   A O   1 
ATOM   5090 C CB  . THR   A 1 632 ? 175.516 172.646 151.881 1.00 163.70 ? 658 THR   A CB  1 
ATOM   5091 O OG1 . THR   A 1 632 ? 176.589 171.716 151.687 1.00 163.43 ? 658 THR   A OG1 1 
ATOM   5092 C CG2 . THR   A 1 632 ? 174.335 171.926 152.522 1.00 159.64 ? 658 THR   A CG2 1 
ATOM   5093 N N   . PHE   A 1 633 ? 174.339 175.494 151.128 1.00 161.78 ? 659 PHE   A N   1 
ATOM   5094 C CA  . PHE   A 1 633 ? 173.322 176.524 151.319 1.00 159.73 ? 659 PHE   A CA  1 
ATOM   5095 C C   . PHE   A 1 633 ? 172.623 176.853 150.006 1.00 158.21 ? 659 PHE   A C   1 
ATOM   5096 O O   . PHE   A 1 633 ? 171.388 176.936 149.945 1.00 154.26 ? 659 PHE   A O   1 
ATOM   5097 C CB  . PHE   A 1 633 ? 173.957 177.778 151.921 1.00 161.06 ? 659 PHE   A CB  1 
ATOM   5098 C CG  . PHE   A 1 633 ? 172.959 178.807 152.370 1.00 161.63 ? 659 PHE   A CG  1 
ATOM   5099 C CD1 . PHE   A 1 633 ? 172.447 178.777 153.656 1.00 158.80 ? 659 PHE   A CD1 1 
ATOM   5100 C CD2 . PHE   A 1 633 ? 172.536 179.806 151.510 1.00 164.06 ? 659 PHE   A CD2 1 
ATOM   5101 C CE1 . PHE   A 1 633 ? 171.531 179.721 154.074 1.00 161.03 ? 659 PHE   A CE1 1 
ATOM   5102 C CE2 . PHE   A 1 633 ? 171.619 180.753 151.923 1.00 165.56 ? 659 PHE   A CE2 1 
ATOM   5103 C CZ  . PHE   A 1 633 ? 171.116 180.710 153.207 1.00 165.19 ? 659 PHE   A CZ  1 
ATOM   5104 N N   . LEU   A 1 634 ? 173.403 177.047 148.939 1.00 164.14 ? 660 LEU   A N   1 
ATOM   5105 C CA  . LEU   A 1 634 ? 172.811 177.354 147.640 1.00 168.45 ? 660 LEU   A CA  1 
ATOM   5106 C C   . LEU   A 1 634 ? 171.951 176.200 147.141 1.00 164.22 ? 660 LEU   A C   1 
ATOM   5107 O O   . LEU   A 1 634 ? 170.872 176.420 146.579 1.00 160.27 ? 660 LEU   A O   1 
ATOM   5108 C CB  . LEU   A 1 634 ? 173.908 177.686 146.626 1.00 172.58 ? 660 LEU   A CB  1 
ATOM   5109 C CG  . LEU   A 1 634 ? 174.727 178.957 146.878 1.00 174.55 ? 660 LEU   A CG  1 
ATOM   5110 C CD1 . LEU   A 1 634 ? 175.859 179.067 145.868 1.00 176.39 ? 660 LEU   A CD1 1 
ATOM   5111 C CD2 . LEU   A 1 634 ? 173.854 180.205 146.832 1.00 175.31 ? 660 LEU   A CD2 1 
ATOM   5112 N N   . ARG   A 1 635 ? 172.414 174.962 147.332 1.00 163.60 ? 661 ARG   A N   1 
ATOM   5113 C CA  . ARG   A 1 635 ? 171.631 173.805 146.911 1.00 162.17 ? 661 ARG   A CA  1 
ATOM   5114 C C   . ARG   A 1 635 ? 170.316 173.724 147.676 1.00 156.81 ? 661 ARG   A C   1 
ATOM   5115 O O   . ARG   A 1 635 ? 169.267 173.430 147.091 1.00 156.61 ? 661 ARG   A O   1 
ATOM   5116 C CB  . ARG   A 1 635 ? 172.449 172.528 147.104 1.00 163.71 ? 661 ARG   A CB  1 
ATOM   5117 C CG  . ARG   A 1 635 ? 171.820 171.278 146.500 1.00 163.28 ? 661 ARG   A CG  1 
ATOM   5118 C CD  . ARG   A 1 635 ? 172.667 170.030 146.737 1.00 165.39 ? 661 ARG   A CD  1 
ATOM   5119 N NE  . ARG   A 1 635 ? 173.937 170.060 146.015 1.00 169.24 ? 661 ARG   A NE  1 
ATOM   5120 C CZ  . ARG   A 1 635 ? 175.089 170.523 146.490 1.00 168.91 ? 661 ARG   A CZ  1 
ATOM   5121 N NH1 . ARG   A 1 635 ? 175.190 171.040 147.707 1.00 167.09 ? 661 ARG   A NH1 1 
ATOM   5122 N NH2 . ARG   A 1 635 ? 176.173 170.470 145.721 1.00 168.90 ? 661 ARG   A NH2 1 
ATOM   5123 N N   . ARG   A 1 636 ? 170.354 173.970 148.988 1.00 153.58 ? 662 ARG   A N   1 
ATOM   5124 C CA  . ARG   A 1 636 ? 169.127 173.942 149.778 1.00 155.59 ? 662 ARG   A CA  1 
ATOM   5125 C C   . ARG   A 1 636 ? 168.159 175.024 149.320 1.00 154.43 ? 662 ARG   A C   1 
ATOM   5126 O O   . ARG   A 1 636 ? 166.953 174.777 149.199 1.00 154.46 ? 662 ARG   A O   1 
ATOM   5127 C CB  . ARG   A 1 636 ? 169.454 174.106 151.263 1.00 160.20 ? 662 ARG   A CB  1 
ATOM   5128 C CG  . ARG   A 1 636 ? 168.256 173.927 152.189 1.00 161.03 ? 662 ARG   A CG  1 
ATOM   5129 C CD  . ARG   A 1 636 ? 168.660 173.990 153.654 1.00 162.20 ? 662 ARG   A CD  1 
ATOM   5130 N NE  . ARG   A 1 636 ? 167.515 173.819 154.543 1.00 162.14 ? 662 ARG   A NE  1 
ATOM   5131 C CZ  . ARG   A 1 636 ? 167.572 173.842 155.870 1.00 162.04 ? 662 ARG   A CZ  1 
ATOM   5132 N NH1 . ARG   A 1 636 ? 168.712 174.031 156.516 1.00 161.30 ? 662 ARG   A NH1 1 
ATOM   5133 N NH2 . ARG   A 1 636 ? 166.453 173.670 156.568 1.00 159.98 ? 662 ARG   A NH2 1 
ATOM   5134 N N   . GLN   A 1 637 ? 168.668 176.231 149.058 1.00 151.50 ? 663 GLN   A N   1 
ATOM   5135 C CA  . GLN   A 1 637 ? 167.800 177.305 148.584 1.00 149.00 ? 663 GLN   A CA  1 
ATOM   5136 C C   . GLN   A 1 637 ? 167.184 176.959 147.232 1.00 149.09 ? 663 GLN   A C   1 
ATOM   5137 O O   . GLN   A 1 637 ? 165.989 177.190 147.008 1.00 146.29 ? 663 GLN   A O   1 
ATOM   5138 C CB  . GLN   A 1 637 ? 168.588 178.613 148.499 1.00 148.48 ? 663 GLN   A CB  1 
ATOM   5139 C CG  . GLN   A 1 637 ? 167.748 179.828 148.132 1.00 149.45 ? 663 GLN   A CG  1 
ATOM   5140 C CD  . GLN   A 1 637 ? 168.531 181.124 148.213 1.00 149.44 ? 663 GLN   A CD  1 
ATOM   5141 O OE1 . GLN   A 1 637 ? 169.703 181.133 148.589 1.00 150.59 ? 663 GLN   A OE1 1 
ATOM   5142 N NE2 . GLN   A 1 637 ? 167.884 182.229 147.858 1.00 147.26 ? 663 GLN   A NE2 1 
ATOM   5143 N N   . GLN   A 1 638 ? 167.986 176.405 146.319 1.00 152.14 ? 664 GLN   A N   1 
ATOM   5144 C CA  . GLN   A 1 638 ? 167.472 176.033 145.005 1.00 153.31 ? 664 GLN   A CA  1 
ATOM   5145 C C   . GLN   A 1 638 ? 166.410 174.947 145.117 1.00 152.76 ? 664 GLN   A C   1 
ATOM   5146 O O   . GLN   A 1 638 ? 165.378 175.005 144.437 1.00 151.88 ? 664 GLN   A O   1 
ATOM   5147 C CB  . GLN   A 1 638 ? 168.623 175.571 144.110 1.00 156.14 ? 664 GLN   A CB  1 
ATOM   5148 C CG  . GLN   A 1 638 ? 168.229 175.294 142.664 1.00 158.30 ? 664 GLN   A CG  1 
ATOM   5149 C CD  . GLN   A 1 638 ? 169.422 174.950 141.794 1.00 158.62 ? 664 GLN   A CD  1 
ATOM   5150 O OE1 . GLN   A 1 638 ? 170.570 175.043 142.228 1.00 161.43 ? 664 GLN   A OE1 1 
ATOM   5151 N NE2 . GLN   A 1 638 ? 169.154 174.546 140.557 1.00 152.85 ? 664 GLN   A NE2 1 
ATOM   5152 N N   . ARG   A 1 639 ? 166.650 173.942 145.964 1.00 152.47 ? 665 ARG   A N   1 
ATOM   5153 C CA  . ARG   A 1 639 ? 165.666 172.883 146.157 1.00 149.46 ? 665 ARG   A CA  1 
ATOM   5154 C C   . ARG   A 1 639 ? 164.376 173.437 146.747 1.00 149.76 ? 665 ARG   A C   1 
ATOM   5155 O O   . ARG   A 1 639 ? 163.277 173.039 146.341 1.00 149.27 ? 665 ARG   A O   1 
ATOM   5156 C CB  . ARG   A 1 639 ? 166.247 171.792 147.057 1.00 151.69 ? 665 ARG   A CB  1 
ATOM   5157 C CG  . ARG   A 1 639 ? 165.372 170.555 147.196 1.00 156.11 ? 665 ARG   A CG  1 
ATOM   5158 C CD  . ARG   A 1 639 ? 166.038 169.502 148.068 1.00 160.14 ? 665 ARG   A CD  1 
ATOM   5159 N NE  . ARG   A 1 639 ? 165.188 168.331 148.262 1.00 163.23 ? 665 ARG   A NE  1 
ATOM   5160 C CZ  . ARG   A 1 639 ? 165.067 167.322 147.408 1.00 162.41 ? 665 ARG   A CZ  1 
ATOM   5161 N NH1 . ARG   A 1 639 ? 165.722 167.298 146.256 1.00 160.57 ? 665 ARG   A NH1 1 
ATOM   5162 N NH2 . ARG   A 1 639 ? 164.264 166.307 147.715 1.00 163.00 ? 665 ARG   A NH2 1 
ATOM   5163 N N   . LEU   A 1 640 ? 164.489 174.354 147.712 1.00 149.47 ? 666 LEU   A N   1 
ATOM   5164 C CA  . LEU   A 1 640 ? 163.296 174.956 148.297 1.00 149.87 ? 666 LEU   A CA  1 
ATOM   5165 C C   . LEU   A 1 640 ? 162.512 175.741 147.254 1.00 147.47 ? 666 LEU   A C   1 
ATOM   5166 O O   . LEU   A 1 640 ? 161.280 175.655 147.199 1.00 146.89 ? 666 LEU   A O   1 
ATOM   5167 C CB  . LEU   A 1 640 ? 163.689 175.858 149.469 1.00 151.58 ? 666 LEU   A CB  1 
ATOM   5168 C CG  . LEU   A 1 640 ? 162.562 176.545 150.248 1.00 151.65 ? 666 LEU   A CG  1 
ATOM   5169 C CD1 . LEU   A 1 640 ? 161.617 175.527 150.870 1.00 149.88 ? 666 LEU   A CD1 1 
ATOM   5170 C CD2 . LEU   A 1 640 ? 163.144 177.456 151.317 1.00 147.05 ? 666 LEU   A CD2 1 
ATOM   5171 N N   . GLN   A 1 641 ? 163.210 176.510 146.416 1.00 147.31 ? 667 GLN   A N   1 
ATOM   5172 C CA  . GLN   A 1 641 ? 162.530 177.263 145.366 1.00 148.54 ? 667 GLN   A CA  1 
ATOM   5173 C C   . GLN   A 1 641 ? 161.850 176.330 144.371 1.00 146.40 ? 667 GLN   A C   1 
ATOM   5174 O O   . GLN   A 1 641 ? 160.726 176.595 143.928 1.00 143.55 ? 667 GLN   A O   1 
ATOM   5175 C CB  . GLN   A 1 641 ? 163.523 178.179 144.653 1.00 152.84 ? 667 GLN   A CB  1 
ATOM   5176 C CG  . GLN   A 1 641 ? 164.006 179.344 145.503 1.00 154.63 ? 667 GLN   A CG  1 
ATOM   5177 C CD  . GLN   A 1 641 ? 165.075 180.167 144.812 1.00 157.04 ? 667 GLN   A CD  1 
ATOM   5178 O OE1 . GLN   A 1 641 ? 165.369 179.962 143.635 1.00 157.53 ? 667 GLN   A OE1 1 
ATOM   5179 N NE2 . GLN   A 1 641 ? 165.664 181.106 145.544 1.00 156.01 ? 667 GLN   A NE2 1 
ATOM   5180 N N   . GLU   A 1 642 ? 162.519 175.235 144.003 1.00 149.53 ? 668 GLU   A N   1 
ATOM   5181 C CA  . GLU   A 1 642 ? 161.920 174.279 143.078 1.00 150.28 ? 668 GLU   A CA  1 
ATOM   5182 C C   . GLU   A 1 642 ? 160.670 173.645 143.677 1.00 147.96 ? 668 GLU   A C   1 
ATOM   5183 O O   . GLU   A 1 642 ? 159.650 173.497 142.993 1.00 145.63 ? 668 GLU   A O   1 
ATOM   5184 C CB  . GLU   A 1 642 ? 162.943 173.205 142.704 1.00 151.69 ? 668 GLU   A CB  1 
ATOM   5185 C CG  . GLU   A 1 642 ? 162.473 172.237 141.626 1.00 151.20 ? 668 GLU   A CG  1 
ATOM   5186 C CD  . GLU   A 1 642 ? 163.557 171.263 141.206 1.00 148.38 ? 668 GLU   A CD  1 
ATOM   5187 O OE1 . GLU   A 1 642 ? 164.679 171.349 141.747 1.00 150.65 ? 668 GLU   A OE1 1 
ATOM   5188 O OE2 . GLU   A 1 642 ? 163.285 170.409 140.335 1.00 142.14 ? 668 GLU   A OE2 1 
ATOM   5189 N N   . ILE   A 1 643 ? 160.729 173.265 144.956 1.00 148.46 ? 669 ILE   A N   1 
ATOM   5190 C CA  . ILE   A 1 643 ? 159.562 172.677 145.609 1.00 149.88 ? 669 ILE   A CA  1 
ATOM   5191 C C   . ILE   A 1 643 ? 158.426 173.690 145.675 1.00 147.03 ? 669 ILE   A C   1 
ATOM   5192 O O   . ILE   A 1 643 ? 157.257 173.348 145.459 1.00 144.68 ? 669 ILE   A O   1 
ATOM   5193 C CB  . ILE   A 1 643 ? 159.940 172.148 147.007 1.00 151.79 ? 669 ILE   A CB  1 
ATOM   5194 C CG1 . ILE   A 1 643 ? 160.884 170.944 146.883 1.00 150.35 ? 669 ILE   A CG1 1 
ATOM   5195 C CG2 . ILE   A 1 643 ? 158.680 171.766 147.792 1.00 149.59 ? 669 ILE   A CG2 1 
ATOM   5196 C CD1 . ILE   A 1 643 ? 161.618 170.587 148.165 1.00 150.08 ? 669 ILE   A CD1 1 
ATOM   5197 N N   . GLU   A 1 644 ? 158.747 174.948 145.984 1.00 147.24 ? 670 GLU   A N   1 
ATOM   5198 C CA  . GLU   A 1 644 ? 157.719 175.982 146.051 1.00 145.12 ? 670 GLU   A CA  1 
ATOM   5199 C C   . GLU   A 1 644 ? 157.062 176.189 144.693 1.00 141.60 ? 670 GLU   A C   1 
ATOM   5200 O O   . GLU   A 1 644 ? 155.838 176.339 144.603 1.00 136.51 ? 670 GLU   A O   1 
ATOM   5201 C CB  . GLU   A 1 644 ? 158.327 177.288 146.562 1.00 146.11 ? 670 GLU   A CB  1 
ATOM   5202 C CG  . GLU   A 1 644 ? 157.309 178.381 146.853 1.00 147.07 ? 670 GLU   A CG  1 
ATOM   5203 C CD  . GLU   A 1 644 ? 157.941 179.617 147.463 1.00 148.74 ? 670 GLU   A CD  1 
ATOM   5204 O OE1 . GLU   A 1 644 ? 159.175 179.623 147.652 1.00 148.40 ? 670 GLU   A OE1 1 
ATOM   5205 O OE2 . GLU   A 1 644 ? 157.202 180.581 147.755 1.00 148.68 ? 670 GLU   A OE2 1 
ATOM   5206 N N   . ARG   A 1 645 ? 157.861 176.204 143.624 1.00 142.49 ? 671 ARG   A N   1 
ATOM   5207 C CA  . ARG   A 1 645 ? 157.299 176.316 142.283 1.00 143.14 ? 671 ARG   A CA  1 
ATOM   5208 C C   . ARG   A 1 645 ? 156.413 175.118 141.962 1.00 144.95 ? 671 ARG   A C   1 
ATOM   5209 O O   . ARG   A 1 645 ? 155.345 175.270 141.358 1.00 140.42 ? 671 ARG   A O   1 
ATOM   5210 C CB  . ARG   A 1 645 ? 158.427 176.443 141.256 1.00 146.17 ? 671 ARG   A CB  1 
ATOM   5211 C CG  . ARG   A 1 645 ? 157.966 176.653 139.817 1.00 147.18 ? 671 ARG   A CG  1 
ATOM   5212 C CD  . ARG   A 1 645 ? 159.152 176.752 138.871 1.00 149.87 ? 671 ARG   A CD  1 
ATOM   5213 N NE  . ARG   A 1 645 ? 158.745 176.708 137.471 1.00 152.07 ? 671 ARG   A NE  1 
ATOM   5214 C CZ  . ARG   A 1 645 ? 159.578 176.668 136.439 1.00 150.26 ? 671 ARG   A CZ  1 
ATOM   5215 N NH1 . ARG   A 1 645 ? 160.893 176.664 136.603 1.00 150.18 ? 671 ARG   A NH1 1 
ATOM   5216 N NH2 . ARG   A 1 645 ? 159.080 176.627 135.206 1.00 148.68 ? 671 ARG   A NH2 1 
ATOM   5217 N N   . ARG   A 1 646 ? 156.846 173.916 142.353 1.00 148.74 ? 672 ARG   A N   1 
ATOM   5218 C CA  . ARG   A 1 646 ? 156.056 172.719 142.081 1.00 147.93 ? 672 ARG   A CA  1 
ATOM   5219 C C   . ARG   A 1 646 ? 154.711 172.769 142.797 1.00 142.55 ? 672 ARG   A C   1 
ATOM   5220 O O   . ARG   A 1 646 ? 153.673 172.457 142.202 1.00 136.71 ? 672 ARG   A O   1 
ATOM   5221 C CB  . ARG   A 1 646 ? 156.842 171.474 142.502 1.00 149.46 ? 672 ARG   A CB  1 
ATOM   5222 C CG  . ARG   A 1 646 ? 156.164 170.141 142.183 1.00 151.09 ? 672 ARG   A CG  1 
ATOM   5223 C CD  . ARG   A 1 646 ? 156.979 168.969 142.707 1.00 153.12 ? 672 ARG   A CD  1 
ATOM   5224 N NE  . ARG   A 1 646 ? 156.231 167.717 142.658 1.00 157.86 ? 672 ARG   A NE  1 
ATOM   5225 C CZ  . ARG   A 1 646 ? 156.628 166.573 143.201 1.00 158.44 ? 672 ARG   A CZ  1 
ATOM   5226 N NH1 . ARG   A 1 646 ? 157.774 166.474 143.859 1.00 158.95 ? 672 ARG   A NH1 1 
ATOM   5227 N NH2 . ARG   A 1 646 ? 155.853 165.499 143.087 1.00 156.42 ? 672 ARG   A NH2 1 
ATOM   5228 N N   . ARG   A 1 647 ? 154.711 173.155 144.075 1.00 143.81 ? 673 ARG   A N   1 
ATOM   5229 C CA  . ARG   A 1 647 ? 153.469 173.174 144.842 1.00 139.29 ? 673 ARG   A CA  1 
ATOM   5230 C C   . ARG   A 1 647 ? 152.474 174.171 144.264 1.00 136.62 ? 673 ARG   A C   1 
ATOM   5231 O O   . ARG   A 1 647 ? 151.280 173.869 144.145 1.00 136.62 ? 673 ARG   A O   1 
ATOM   5232 C CB  . ARG   A 1 647 ? 153.765 173.501 146.305 1.00 142.31 ? 673 ARG   A CB  1 
ATOM   5233 C CG  . ARG   A 1 647 ? 154.516 172.406 147.045 1.00 146.10 ? 673 ARG   A CG  1 
ATOM   5234 C CD  . ARG   A 1 647 ? 154.913 172.851 148.443 1.00 148.68 ? 673 ARG   A CD  1 
ATOM   5235 N NE  . ARG   A 1 647 ? 155.732 171.856 149.127 1.00 149.67 ? 673 ARG   A NE  1 
ATOM   5236 C CZ  . ARG   A 1 647 ? 156.224 171.991 150.352 1.00 148.09 ? 673 ARG   A CZ  1 
ATOM   5237 N NH1 . ARG   A 1 647 ? 156.001 173.076 151.078 1.00 146.55 ? 673 ARG   A NH1 1 
ATOM   5238 N NH2 . ARG   A 1 647 ? 156.962 171.010 150.864 1.00 145.81 ? 673 ARG   A NH2 1 
ATOM   5239 N N   . ASN   A 1 648 ? 152.945 175.359 143.894 1.00 136.34 ? 674 ASN   A N   1 
ATOM   5240 C CA  . ASN   A 1 648 ? 152.083 176.398 143.331 1.00 134.96 ? 674 ASN   A CA  1 
ATOM   5241 C C   . ASN   A 1 648 ? 151.970 176.226 141.814 1.00 133.38 ? 674 ASN   A C   1 
ATOM   5242 O O   . ASN   A 1 648 ? 152.374 177.079 141.023 1.00 133.77 ? 674 ASN   A O   1 
ATOM   5243 C CB  . ASN   A 1 648 ? 152.619 177.777 143.699 1.00 135.33 ? 674 ASN   A CB  1 
ATOM   5244 C CG  . ASN   A 1 648 ? 153.057 177.861 145.148 1.00 133.19 ? 674 ASN   A CG  1 
ATOM   5245 O OD1 . ASN   A 1 648 ? 154.160 178.317 145.447 1.00 135.98 ? 674 ASN   A OD1 1 
ATOM   5246 N ND2 . ASN   A 1 648 ? 152.198 177.412 146.055 1.00 130.68 ? 674 ASN   A ND2 1 
ATOM   5247 N N   . THR   A 1 649 ? 151.400 175.086 141.426 1.00 135.83 ? 675 THR   A N   1 
ATOM   5248 C CA  . THR   A 1 649 ? 151.258 174.679 140.038 1.00 142.86 ? 675 THR   A CA  1 
ATOM   5249 C C   . THR   A 1 649 ? 149.778 174.491 139.716 1.00 144.79 ? 675 THR   A C   1 
ATOM   5250 O O   . THR   A 1 649 ? 149.096 173.747 140.434 1.00 143.36 ? 675 THR   A O   1 
ATOM   5251 C CB  . THR   A 1 649 ? 152.017 173.368 139.776 1.00 143.70 ? 675 THR   A CB  1 
ATOM   5252 O OG1 . THR   A 1 649 ? 153.381 173.511 140.193 1.00 139.84 ? 675 THR   A OG1 1 
ATOM   5253 C CG2 . THR   A 1 649 ? 151.978 173.005 138.298 1.00 142.29 ? 675 THR   A CG2 1 
ATOM   5254 N N   . PRO   A 1 650 ? 149.233 175.130 138.674 1.00 144.04 ? 676 PRO   A N   1 
ATOM   5255 C CA  . PRO   A 1 650 ? 147.801 174.970 138.403 1.00 139.34 ? 676 PRO   A CA  1 
ATOM   5256 C C   . PRO   A 1 650 ? 147.462 173.552 137.971 1.00 140.88 ? 676 PRO   A C   1 
ATOM   5257 O O   . PRO   A 1 650 ? 148.303 172.815 137.452 1.00 140.73 ? 676 PRO   A O   1 
ATOM   5258 C CB  . PRO   A 1 650 ? 147.536 175.974 137.276 1.00 135.61 ? 676 PRO   A CB  1 
ATOM   5259 C CG  . PRO   A 1 650 ? 148.821 176.088 136.579 1.00 138.56 ? 676 PRO   A CG  1 
ATOM   5260 C CD  . PRO   A 1 650 ? 149.872 175.972 137.642 1.00 141.33 ? 676 PRO   A CD  1 
ATOM   5261 N N   . PHE   A 1 651 ? 146.201 173.178 138.199 1.00 141.54 ? 677 PHE   A N   1 
ATOM   5262 C CA  . PHE   A 1 651 ? 145.770 171.807 137.943 1.00 144.01 ? 677 PHE   A CA  1 
ATOM   5263 C C   . PHE   A 1 651 ? 145.855 171.460 136.461 1.00 138.33 ? 677 PHE   A C   1 
ATOM   5264 O O   . PHE   A 1 651 ? 146.193 170.325 136.102 1.00 135.45 ? 677 PHE   A O   1 
ATOM   5265 C CB  . PHE   A 1 651 ? 144.344 171.610 138.459 1.00 145.02 ? 677 PHE   A CB  1 
ATOM   5266 C CG  . PHE   A 1 651 ? 143.811 170.219 138.260 1.00 148.89 ? 677 PHE   A CG  1 
ATOM   5267 C CD1 . PHE   A 1 651 ? 144.155 169.199 139.131 1.00 146.97 ? 677 PHE   A CD1 1 
ATOM   5268 C CD2 . PHE   A 1 651 ? 142.957 169.934 137.207 1.00 147.58 ? 677 PHE   A CD2 1 
ATOM   5269 C CE1 . PHE   A 1 651 ? 143.663 167.920 138.952 1.00 147.36 ? 677 PHE   A CE1 1 
ATOM   5270 C CE2 . PHE   A 1 651 ? 142.462 168.657 137.023 1.00 144.44 ? 677 PHE   A CE2 1 
ATOM   5271 C CZ  . PHE   A 1 651 ? 142.815 167.649 137.897 1.00 145.52 ? 677 PHE   A CZ  1 
ATOM   5272 N N   . HIS   A 1 652 ? 145.534 172.417 135.587 1.00 131.47 ? 678 HIS   A N   1 
ATOM   5273 C CA  . HIS   A 1 652 ? 145.552 172.137 134.153 1.00 130.17 ? 678 HIS   A CA  1 
ATOM   5274 C C   . HIS   A 1 652 ? 146.955 171.782 133.672 1.00 133.94 ? 678 HIS   A C   1 
ATOM   5275 O O   . HIS   A 1 652 ? 147.120 170.889 132.831 1.00 137.95 ? 678 HIS   A O   1 
ATOM   5276 C CB  . HIS   A 1 652 ? 144.981 173.317 133.357 1.00 132.20 ? 678 HIS   A CB  1 
ATOM   5277 C CG  . HIS   A 1 652 ? 145.600 174.644 133.678 1.00 139.68 ? 678 HIS   A CG  1 
ATOM   5278 N ND1 . HIS   A 1 652 ? 146.845 175.020 133.222 1.00 142.95 ? 678 HIS   A ND1 1 
ATOM   5279 C CD2 . HIS   A 1 652 ? 145.130 175.691 134.396 1.00 143.03 ? 678 HIS   A CD2 1 
ATOM   5280 C CE1 . HIS   A 1 652 ? 147.120 176.238 133.654 1.00 143.29 ? 678 HIS   A CE1 1 
ATOM   5281 N NE2 . HIS   A 1 652 ? 146.096 176.668 134.369 1.00 143.69 ? 678 HIS   A NE2 1 
ATOM   5282 N N   . GLU   A 1 653 ? 147.981 172.457 134.198 1.00 134.39 ? 679 GLU   A N   1 
ATOM   5283 C CA  . GLU   A 1 653 ? 149.350 172.106 133.831 1.00 138.47 ? 679 GLU   A CA  1 
ATOM   5284 C C   . GLU   A 1 653 ? 149.689 170.685 134.262 1.00 135.65 ? 679 GLU   A C   1 
ATOM   5285 O O   . GLU   A 1 653 ? 150.317 169.931 133.507 1.00 134.67 ? 679 GLU   A O   1 
ATOM   5286 C CB  . GLU   A 1 653 ? 150.335 173.096 134.453 1.00 141.47 ? 679 GLU   A CB  1 
ATOM   5287 C CG  . GLU   A 1 653 ? 150.445 174.415 133.710 1.00 144.75 ? 679 GLU   A CG  1 
ATOM   5288 C CD  . GLU   A 1 653 ? 151.441 175.363 134.348 1.00 149.20 ? 679 GLU   A CD  1 
ATOM   5289 O OE1 . GLU   A 1 653 ? 152.146 174.942 135.289 1.00 149.77 ? 679 GLU   A OE1 1 
ATOM   5290 O OE2 . GLU   A 1 653 ? 151.520 176.529 133.908 1.00 147.28 ? 679 GLU   A OE2 1 
ATOM   5291 N N   . ARG   A 1 654 ? 149.286 170.303 135.476 1.00 131.13 ? 680 ARG   A N   1 
ATOM   5292 C CA  . ARG   A 1 654 ? 149.564 168.954 135.956 1.00 134.04 ? 680 ARG   A CA  1 
ATOM   5293 C C   . ARG   A 1 654 ? 148.862 167.912 135.095 1.00 130.39 ? 680 ARG   A C   1 
ATOM   5294 O O   . ARG   A 1 654 ? 149.451 166.880 134.747 1.00 129.39 ? 680 ARG   A O   1 
ATOM   5295 C CB  . ARG   A 1 654 ? 149.136 168.822 137.418 1.00 137.90 ? 680 ARG   A CB  1 
ATOM   5296 C CG  . ARG   A 1 654 ? 149.812 169.813 138.362 1.00 139.61 ? 680 ARG   A CG  1 
ATOM   5297 C CD  . ARG   A 1 654 ? 149.296 169.699 139.791 1.00 140.11 ? 680 ARG   A CD  1 
ATOM   5298 N NE  . ARG   A 1 654 ? 149.712 168.460 140.445 1.00 146.72 ? 680 ARG   A NE  1 
ATOM   5299 C CZ  . ARG   A 1 654 ? 149.030 167.320 140.453 1.00 150.29 ? 680 ARG   A CZ  1 
ATOM   5300 N NH1 . ARG   A 1 654 ? 147.866 167.194 139.831 1.00 147.12 ? 680 ARG   A NH1 1 
ATOM   5301 N NH2 . ARG   A 1 654 ? 149.529 166.274 141.104 1.00 150.83 ? 680 ARG   A NH2 1 
ATOM   5302 N N   . PHE   A 1 655 ? 147.602 168.168 134.739 1.00 126.45 ? 681 PHE   A N   1 
ATOM   5303 C CA  . PHE   A 1 655 ? 146.865 167.238 133.889 1.00 127.39 ? 681 PHE   A CA  1 
ATOM   5304 C C   . PHE   A 1 655 ? 147.515 167.117 132.516 1.00 123.29 ? 681 PHE   A C   1 
ATOM   5305 O O   . PHE   A 1 655 ? 147.614 166.015 131.958 1.00 123.86 ? 681 PHE   A O   1 
ATOM   5306 C CB  . PHE   A 1 655 ? 145.414 167.702 133.765 1.00 132.28 ? 681 PHE   A CB  1 
ATOM   5307 C CG  . PHE   A 1 655 ? 144.509 166.711 133.091 1.00 132.51 ? 681 PHE   A CG  1 
ATOM   5308 C CD1 . PHE   A 1 655 ? 143.977 165.646 133.798 1.00 131.38 ? 681 PHE   A CD1 1 
ATOM   5309 C CD2 . PHE   A 1 655 ? 144.176 166.856 131.755 1.00 128.76 ? 681 PHE   A CD2 1 
ATOM   5310 C CE1 . PHE   A 1 655 ? 143.138 164.738 133.181 1.00 129.04 ? 681 PHE   A CE1 1 
ATOM   5311 C CE2 . PHE   A 1 655 ? 143.337 165.952 131.134 1.00 128.45 ? 681 PHE   A CE2 1 
ATOM   5312 C CZ  . PHE   A 1 655 ? 142.816 164.892 131.849 1.00 129.45 ? 681 PHE   A CZ  1 
ATOM   5313 N N   . PHE   A 1 656 ? 147.962 168.242 131.955 1.00 120.02 ? 682 PHE   A N   1 
ATOM   5314 C CA  . PHE   A 1 656 ? 148.630 168.210 130.660 1.00 121.54 ? 682 PHE   A CA  1 
ATOM   5315 C C   . PHE   A 1 656 ? 149.919 167.401 130.729 1.00 121.42 ? 682 PHE   A C   1 
ATOM   5316 O O   . PHE   A 1 656 ? 150.209 166.603 129.829 1.00 121.91 ? 682 PHE   A O   1 
ATOM   5317 C CB  . PHE   A 1 656 ? 148.909 169.637 130.190 1.00 128.20 ? 682 PHE   A CB  1 
ATOM   5318 C CG  . PHE   A 1 656 ? 149.250 169.744 128.731 1.00 132.05 ? 682 PHE   A CG  1 
ATOM   5319 C CD1 . PHE   A 1 656 ? 148.253 169.735 127.771 1.00 130.58 ? 682 PHE   A CD1 1 
ATOM   5320 C CD2 . PHE   A 1 656 ? 150.567 169.867 128.321 1.00 129.14 ? 682 PHE   A CD2 1 
ATOM   5321 C CE1 . PHE   A 1 656 ? 148.563 169.837 126.428 1.00 128.85 ? 682 PHE   A CE1 1 
ATOM   5322 C CE2 . PHE   A 1 656 ? 150.883 169.971 126.980 1.00 127.39 ? 682 PHE   A CE2 1 
ATOM   5323 C CZ  . PHE   A 1 656 ? 149.880 169.956 126.032 1.00 128.27 ? 682 PHE   A CZ  1 
ATOM   5324 N N   . ARG   A 1 657 ? 150.703 167.590 131.794 1.00 121.10 ? 683 ARG   A N   1 
ATOM   5325 C CA  . ARG   A 1 657 ? 151.930 166.815 131.946 1.00 124.43 ? 683 ARG   A CA  1 
ATOM   5326 C C   . ARG   A 1 657 ? 151.626 165.329 132.086 1.00 121.54 ? 683 ARG   A C   1 
ATOM   5327 O O   . ARG   A 1 657 ? 152.342 164.484 131.535 1.00 124.41 ? 683 ARG   A O   1 
ATOM   5328 C CB  . ARG   A 1 657 ? 152.726 167.318 133.150 1.00 128.82 ? 683 ARG   A CB  1 
ATOM   5329 C CG  . ARG   A 1 657 ? 153.363 168.684 132.945 1.00 132.10 ? 683 ARG   A CG  1 
ATOM   5330 C CD  . ARG   A 1 657 ? 154.199 169.097 134.146 1.00 135.31 ? 683 ARG   A CD  1 
ATOM   5331 N NE  . ARG   A 1 657 ? 154.804 170.413 133.968 1.00 139.09 ? 683 ARG   A NE  1 
ATOM   5332 C CZ  . ARG   A 1 657 ? 155.588 171.015 134.854 1.00 138.66 ? 683 ARG   A CZ  1 
ATOM   5333 N NH1 . ARG   A 1 657 ? 155.897 170.449 136.012 1.00 134.72 ? 683 ARG   A NH1 1 
ATOM   5334 N NH2 . ARG   A 1 657 ? 156.077 172.220 134.573 1.00 139.24 ? 683 ARG   A NH2 1 
ATOM   5335 N N   . PHE   A 1 658 ? 150.564 164.994 132.820 1.00 115.98 ? 684 PHE   A N   1 
ATOM   5336 C CA  . PHE   A 1 658 ? 150.164 163.598 132.974 1.00 115.96 ? 684 PHE   A CA  1 
ATOM   5337 C C   . PHE   A 1 658 ? 149.817 162.974 131.625 1.00 117.04 ? 684 PHE   A C   1 
ATOM   5338 O O   . PHE   A 1 658 ? 150.278 161.870 131.294 1.00 116.46 ? 684 PHE   A O   1 
ATOM   5339 C CB  . PHE   A 1 658 ? 148.980 163.530 133.940 1.00 116.57 ? 684 PHE   A CB  1 
ATOM   5340 C CG  . PHE   A 1 658 ? 148.333 162.182 134.032 1.00 114.57 ? 684 PHE   A CG  1 
ATOM   5341 C CD1 . PHE   A 1 658 ? 148.993 161.118 134.619 1.00 115.03 ? 684 PHE   A CD1 1 
ATOM   5342 C CD2 . PHE   A 1 658 ? 147.049 161.987 133.560 1.00 111.31 ? 684 PHE   A CD2 1 
ATOM   5343 C CE1 . PHE   A 1 658 ? 148.390 159.883 134.714 1.00 111.83 ? 684 PHE   A CE1 1 
ATOM   5344 C CE2 . PHE   A 1 658 ? 146.442 160.754 133.653 1.00 109.19 ? 684 PHE   A CE2 1 
ATOM   5345 C CZ  . PHE   A 1 658 ? 147.113 159.701 134.231 1.00 109.75 ? 684 PHE   A CZ  1 
ATOM   5346 N N   . LEU   A 1 659 ? 149.018 163.684 130.824 1.00 114.88 ? 685 LEU   A N   1 
ATOM   5347 C CA  . LEU   A 1 659 ? 148.649 163.169 129.508 1.00 114.81 ? 685 LEU   A CA  1 
ATOM   5348 C C   . LEU   A 1 659 ? 149.871 163.017 128.611 1.00 111.26 ? 685 LEU   A C   1 
ATOM   5349 O O   . LEU   A 1 659 ? 150.004 162.017 127.894 1.00 115.30 ? 685 LEU   A O   1 
ATOM   5350 C CB  . LEU   A 1 659 ? 147.614 164.083 128.848 1.00 116.63 ? 685 LEU   A CB  1 
ATOM   5351 C CG  . LEU   A 1 659 ? 146.135 163.709 129.018 1.00 118.64 ? 685 LEU   A CG  1 
ATOM   5352 C CD1 . LEU   A 1 659 ? 145.798 162.429 128.261 1.00 115.00 ? 685 LEU   A CD1 1 
ATOM   5353 C CD2 . LEU   A 1 659 ? 145.751 163.574 130.488 1.00 121.92 ? 685 LEU   A CD2 1 
ATOM   5354 N N   . LEU   A 1 660 ? 150.773 164.002 128.630 1.00 107.35 ? 686 LEU   A N   1 
ATOM   5355 C CA  . LEU   A 1 660 ? 151.971 163.915 127.801 1.00 113.19 ? 686 LEU   A CA  1 
ATOM   5356 C C   . LEU   A 1 660 ? 152.841 162.733 128.209 1.00 112.10 ? 686 LEU   A C   1 
ATOM   5357 O O   . LEU   A 1 660 ? 153.385 162.028 127.351 1.00 113.03 ? 686 LEU   A O   1 
ATOM   5358 C CB  . LEU   A 1 660 ? 152.767 165.220 127.880 1.00 118.61 ? 686 LEU   A CB  1 
ATOM   5359 C CG  . LEU   A 1 660 ? 152.540 166.220 126.740 1.00 121.98 ? 686 LEU   A CG  1 
ATOM   5360 C CD1 . LEU   A 1 660 ? 151.074 166.615 126.596 1.00 122.87 ? 686 LEU   A CD1 1 
ATOM   5361 C CD2 . LEU   A 1 660 ? 153.403 167.455 126.951 1.00 119.55 ? 686 LEU   A CD2 1 
ATOM   5362 N N   . ARG   A 1 661 ? 152.981 162.496 129.515 1.00 110.70 ? 687 ARG   A N   1 
ATOM   5363 C CA  . ARG   A 1 661 ? 153.796 161.376 129.971 1.00 113.25 ? 687 ARG   A CA  1 
ATOM   5364 C C   . ARG   A 1 661 ? 153.190 160.046 129.539 1.00 107.77 ? 687 ARG   A C   1 
ATOM   5365 O O   . ARG   A 1 661 ? 153.908 159.143 129.082 1.00 111.29 ? 687 ARG   A O   1 
ATOM   5366 C CB  . ARG   A 1 661 ? 153.955 161.435 131.490 1.00 115.38 ? 687 ARG   A CB  1 
ATOM   5367 C CG  . ARG   A 1 661 ? 155.017 160.499 132.035 1.00 117.84 ? 687 ARG   A CG  1 
ATOM   5368 C CD  . ARG   A 1 661 ? 155.327 160.766 133.503 1.00 120.32 ? 687 ARG   A CD  1 
ATOM   5369 N NE  . ARG   A 1 661 ? 154.172 160.549 134.371 1.00 125.40 ? 687 ARG   A NE  1 
ATOM   5370 C CZ  . ARG   A 1 661 ? 153.292 161.475 134.738 1.00 128.46 ? 687 ARG   A CZ  1 
ATOM   5371 N NH1 . ARG   A 1 661 ? 153.379 162.730 134.321 1.00 129.04 ? 687 ARG   A NH1 1 
ATOM   5372 N NH2 . ARG   A 1 661 ? 152.294 161.133 135.547 1.00 123.67 ? 687 ARG   A NH2 1 
ATOM   5373 N N   . LYS   A 1 662 ? 151.868 159.907 129.662 1.00 100.35 ? 688 LYS   A N   1 
ATOM   5374 C CA  . LYS   A 1 662 ? 151.237 158.662 129.233 1.00 101.81 ? 688 LYS   A CA  1 
ATOM   5375 C C   . LYS   A 1 662 ? 151.375 158.464 127.726 1.00 103.47 ? 688 LYS   A C   1 
ATOM   5376 O O   . LYS   A 1 662 ? 151.605 157.340 127.256 1.00 104.19 ? 688 LYS   A O   1 
ATOM   5377 C CB  . LYS   A 1 662 ? 149.768 158.646 129.655 1.00 104.21 ? 688 LYS   A CB  1 
ATOM   5378 C CG  . LYS   A 1 662 ? 149.550 158.586 131.166 1.00 106.71 ? 688 LYS   A CG  1 
ATOM   5379 C CD  . LYS   A 1 662 ? 149.953 157.238 131.756 1.00 108.56 ? 688 LYS   A CD  1 
ATOM   5380 C CE  . LYS   A 1 662 ? 149.702 157.183 133.253 1.00 110.21 ? 688 LYS   A CE  1 
ATOM   5381 N NZ  . LYS   A 1 662 ? 150.166 155.902 133.854 1.00 109.26 ? 688 LYS   A NZ  1 
ATOM   5382 N N   . LEU   A 1 663 ? 151.243 159.546 126.953 1.00 106.00 ? 689 LEU   A N   1 
ATOM   5383 C CA  . LEU   A 1 663 ? 151.441 159.449 125.511 1.00 102.34 ? 689 LEU   A CA  1 
ATOM   5384 C C   . LEU   A 1 663 ? 152.861 159.008 125.187 1.00 98.53  ? 689 LEU   A C   1 
ATOM   5385 O O   . LEU   A 1 663 ? 153.076 158.204 124.272 1.00 99.82  ? 689 LEU   A O   1 
ATOM   5386 C CB  . LEU   A 1 663 ? 151.130 160.792 124.849 1.00 107.71 ? 689 LEU   A CB  1 
ATOM   5387 C CG  . LEU   A 1 663 ? 151.324 160.904 123.333 1.00 110.40 ? 689 LEU   A CG  1 
ATOM   5388 C CD1 . LEU   A 1 663 ? 150.484 159.876 122.589 1.00 107.53 ? 689 LEU   A CD1 1 
ATOM   5389 C CD2 . LEU   A 1 663 ? 150.983 162.310 122.864 1.00 109.07 ? 689 LEU   A CD2 1 
ATOM   5390 N N   . TYR   A 1 664 ? 153.843 159.525 125.929 1.00 98.78  ? 690 TYR   A N   1 
ATOM   5391 C CA  . TYR   A 1 664 ? 155.222 159.095 125.727 1.00 102.12 ? 690 TYR   A CA  1 
ATOM   5392 C C   . TYR   A 1 664 ? 155.379 157.607 126.000 1.00 100.59 ? 690 TYR   A C   1 
ATOM   5393 O O   . TYR   A 1 664 ? 156.075 156.904 125.258 1.00 102.70 ? 690 TYR   A O   1 
ATOM   5394 C CB  . TYR   A 1 664 ? 156.166 159.897 126.620 1.00 110.86 ? 690 TYR   A CB  1 
ATOM   5395 C CG  . TYR   A 1 664 ? 157.570 159.333 126.660 1.00 116.82 ? 690 TYR   A CG  1 
ATOM   5396 C CD1 . TYR   A 1 664 ? 158.378 159.349 125.531 1.00 115.96 ? 690 TYR   A CD1 1 
ATOM   5397 C CD2 . TYR   A 1 664 ? 158.087 158.783 127.825 1.00 117.55 ? 690 TYR   A CD2 1 
ATOM   5398 C CE1 . TYR   A 1 664 ? 159.660 158.836 125.561 1.00 118.07 ? 690 TYR   A CE1 1 
ATOM   5399 C CE2 . TYR   A 1 664 ? 159.369 158.268 127.865 1.00 117.42 ? 690 TYR   A CE2 1 
ATOM   5400 C CZ  . TYR   A 1 664 ? 160.150 158.297 126.730 1.00 117.54 ? 690 TYR   A CZ  1 
ATOM   5401 O OH  . TYR   A 1 664 ? 161.427 157.785 126.762 1.00 117.35 ? 690 TYR   A OH  1 
ATOM   5402 N N   . VAL   A 1 665 ? 154.747 157.112 127.066 1.00 101.23 ? 691 VAL   A N   1 
ATOM   5403 C CA  . VAL   A 1 665 ? 154.856 155.690 127.398 1.00 97.35  ? 691 VAL   A CA  1 
ATOM   5404 C C   . VAL   A 1 665 ? 154.277 154.835 126.273 1.00 93.10  ? 691 VAL   A C   1 
ATOM   5405 O O   . VAL   A 1 665 ? 154.894 153.855 125.828 1.00 93.80  ? 691 VAL   A O   1 
ATOM   5406 C CB  . VAL   A 1 665 ? 154.162 155.398 128.741 1.00 97.91  ? 691 VAL   A CB  1 
ATOM   5407 C CG1 . VAL   A 1 665 ? 154.050 153.895 128.978 1.00 92.32  ? 691 VAL   A CG1 1 
ATOM   5408 C CG2 . VAL   A 1 665 ? 154.919 156.055 129.887 1.00 102.33 ? 691 VAL   A CG2 1 
ATOM   5409 N N   . PHE   A 1 666 ? 153.085 155.202 125.790 1.00 92.22  ? 692 PHE   A N   1 
ATOM   5410 C CA  . PHE   A 1 666 ? 152.460 154.434 124.714 1.00 86.60  ? 692 PHE   A CA  1 
ATOM   5411 C C   . PHE   A 1 666 ? 153.303 154.467 123.442 1.00 91.28  ? 692 PHE   A C   1 
ATOM   5412 O O   . PHE   A 1 666 ? 153.491 153.434 122.780 1.00 95.05  ? 692 PHE   A O   1 
ATOM   5413 C CB  . PHE   A 1 666 ? 151.055 154.969 124.429 1.00 89.89  ? 692 PHE   A CB  1 
ATOM   5414 C CG  . PHE   A 1 666 ? 150.003 154.467 125.378 1.00 88.10  ? 692 PHE   A CG  1 
ATOM   5415 C CD1 . PHE   A 1 666 ? 149.517 153.178 125.272 1.00 88.96  ? 692 PHE   A CD1 1 
ATOM   5416 C CD2 . PHE   A 1 666 ? 149.489 155.288 126.363 1.00 92.62  ? 692 PHE   A CD2 1 
ATOM   5417 C CE1 . PHE   A 1 666 ? 148.548 152.717 126.136 1.00 88.87  ? 692 PHE   A CE1 1 
ATOM   5418 C CE2 . PHE   A 1 666 ? 148.520 154.830 127.229 1.00 93.89  ? 692 PHE   A CE2 1 
ATOM   5419 C CZ  . PHE   A 1 666 ? 148.050 153.543 127.116 1.00 90.16  ? 692 PHE   A CZ  1 
ATOM   5420 N N   . ARG   A 1 667 ? 153.821 155.646 123.084 1.00 91.48  ? 693 ARG   A N   1 
ATOM   5421 C CA  . ARG   A 1 667 ? 154.627 155.767 121.874 1.00 89.35  ? 693 ARG   A CA  1 
ATOM   5422 C C   . ARG   A 1 667 ? 155.903 154.942 121.976 1.00 90.16  ? 693 ARG   A C   1 
ATOM   5423 O O   . ARG   A 1 667 ? 156.296 154.273 121.013 1.00 91.62  ? 693 ARG   A O   1 
ATOM   5424 C CB  . ARG   A 1 667 ? 154.956 157.236 121.616 1.00 95.06  ? 693 ARG   A CB  1 
ATOM   5425 C CG  . ARG   A 1 667 ? 155.391 157.540 120.189 1.00 97.03  ? 693 ARG   A CG  1 
ATOM   5426 C CD  . ARG   A 1 667 ? 155.508 159.040 119.946 1.00 100.78 ? 693 ARG   A CD  1 
ATOM   5427 N NE  . ARG   A 1 667 ? 156.744 159.598 120.487 1.00 104.12 ? 693 ARG   A NE  1 
ATOM   5428 C CZ  . ARG   A 1 667 ? 157.880 159.756 119.815 1.00 106.88 ? 693 ARG   A CZ  1 
ATOM   5429 N NH1 . ARG   A 1 667 ? 158.003 159.393 118.547 1.00 104.89 ? 693 ARG   A NH1 1 
ATOM   5430 N NH2 . ARG   A 1 667 ? 158.925 160.297 120.434 1.00 110.49 ? 693 ARG   A NH2 1 
ATOM   5431 N N   . ARG   A 1 668 ? 156.567 154.984 123.134 1.00 92.38  ? 694 ARG   A N   1 
ATOM   5432 C CA  . ARG   A 1 668 ? 157.777 154.194 123.321 1.00 93.37  ? 694 ARG   A CA  1 
ATOM   5433 C C   . ARG   A 1 668 ? 157.481 152.708 123.188 1.00 94.80  ? 694 ARG   A C   1 
ATOM   5434 O O   . ARG   A 1 668 ? 158.234 151.974 122.534 1.00 99.05  ? 694 ARG   A O   1 
ATOM   5435 C CB  . ARG   A 1 668 ? 158.391 154.494 124.688 1.00 98.52  ? 694 ARG   A CB  1 
ATOM   5436 C CG  . ARG   A 1 668 ? 159.798 153.949 124.876 1.00 103.08 ? 694 ARG   A CG  1 
ATOM   5437 C CD  . ARG   A 1 668 ? 160.249 154.056 126.321 1.00 105.91 ? 694 ARG   A CD  1 
ATOM   5438 N NE  . ARG   A 1 668 ? 161.629 153.616 126.486 1.00 112.95 ? 694 ARG   A NE  1 
ATOM   5439 C CZ  . ARG   A 1 668 ? 162.029 152.350 126.495 1.00 111.01 ? 694 ARG   A CZ  1 
ATOM   5440 N NH1 . ARG   A 1 668 ? 161.178 151.347 126.340 1.00 105.98 ? 694 ARG   A NH1 1 
ATOM   5441 N NH2 . ARG   A 1 668 ? 163.321 152.081 126.660 1.00 108.20 ? 694 ARG   A NH2 1 
ATOM   5442 N N   . SER   A 1 669 ? 156.381 152.249 123.795 1.00 94.37  ? 695 SER   A N   1 
ATOM   5443 C CA  . SER   A 1 669 ? 156.017 150.838 123.695 1.00 89.29  ? 695 SER   A CA  1 
ATOM   5444 C C   . SER   A 1 669 ? 155.807 150.429 122.243 1.00 86.23  ? 695 SER   A C   1 
ATOM   5445 O O   . SER   A 1 669 ? 156.355 149.418 121.782 1.00 91.66  ? 695 SER   A O   1 
ATOM   5446 C CB  . SER   A 1 669 ? 154.758 150.565 124.515 1.00 89.84  ? 695 SER   A CB  1 
ATOM   5447 O OG  . SER   A 1 669 ? 154.960 150.878 125.882 1.00 98.67  ? 695 SER   A OG  1 
ATOM   5448 N N   . PHE   A 1 670 ? 155.028 151.220 121.498 1.00 84.31  ? 696 PHE   A N   1 
ATOM   5449 C CA  . PHE   A 1 670 ? 154.732 150.858 120.115 1.00 86.05  ? 696 PHE   A CA  1 
ATOM   5450 C C   . PHE   A 1 670 ? 155.989 150.869 119.250 1.00 86.10  ? 696 PHE   A C   1 
ATOM   5451 O O   . PHE   A 1 670 ? 156.201 149.955 118.443 1.00 87.05  ? 696 PHE   A O   1 
ATOM   5452 C CB  . PHE   A 1 670 ? 153.679 151.803 119.540 1.00 90.27  ? 696 PHE   A CB  1 
ATOM   5453 C CG  . PHE   A 1 670 ? 153.370 151.555 118.090 1.00 95.79  ? 696 PHE   A CG  1 
ATOM   5454 C CD1 . PHE   A 1 670 ? 152.762 150.377 117.688 1.00 96.30  ? 696 PHE   A CD1 1 
ATOM   5455 C CD2 . PHE   A 1 670 ? 153.676 152.504 117.131 1.00 95.77  ? 696 PHE   A CD2 1 
ATOM   5456 C CE1 . PHE   A 1 670 ? 152.474 150.149 116.356 1.00 97.28  ? 696 PHE   A CE1 1 
ATOM   5457 C CE2 . PHE   A 1 670 ? 153.390 152.282 115.798 1.00 98.24  ? 696 PHE   A CE2 1 
ATOM   5458 C CZ  . PHE   A 1 670 ? 152.787 151.103 115.411 1.00 97.70  ? 696 PHE   A CZ  1 
ATOM   5459 N N   . LEU   A 1 671 ? 156.837 151.889 119.404 1.00 83.82  ? 697 LEU   A N   1 
ATOM   5460 C CA  . LEU   A 1 671 ? 158.041 151.962 118.581 1.00 84.71  ? 697 LEU   A CA  1 
ATOM   5461 C C   . LEU   A 1 671 ? 158.999 150.816 118.887 1.00 86.55  ? 697 LEU   A C   1 
ATOM   5462 O O   . LEU   A 1 671 ? 159.577 150.221 117.965 1.00 90.81  ? 697 LEU   A O   1 
ATOM   5463 C CB  . LEU   A 1 671 ? 158.738 153.309 118.773 1.00 87.18  ? 697 LEU   A CB  1 
ATOM   5464 C CG  . LEU   A 1 671 ? 158.384 154.442 117.799 1.00 87.47  ? 697 LEU   A CG  1 
ATOM   5465 C CD1 . LEU   A 1 671 ? 158.824 154.113 116.379 1.00 88.62  ? 697 LEU   A CD1 1 
ATOM   5466 C CD2 . LEU   A 1 671 ? 156.899 154.773 117.827 1.00 89.27  ? 697 LEU   A CD2 1 
ATOM   5467 N N   . MET   A 1 672 ? 159.189 150.493 120.169 1.00 83.59  ? 698 MET   A N   1 
ATOM   5468 C CA  . MET   A 1 672 ? 160.066 149.380 120.513 1.00 83.92  ? 698 MET   A CA  1 
ATOM   5469 C C   . MET   A 1 672 ? 159.521 148.066 119.971 1.00 81.71  ? 698 MET   A C   1 
ATOM   5470 O O   . MET   A 1 672 ? 160.285 147.228 119.474 1.00 85.62  ? 698 MET   A O   1 
ATOM   5471 C CB  . MET   A 1 672 ? 160.249 149.301 122.028 1.00 89.82  ? 698 MET   A CB  1 
ATOM   5472 C CG  . MET   A 1 672 ? 161.061 150.445 122.626 1.00 95.91  ? 698 MET   A CG  1 
ATOM   5473 S SD  . MET   A 1 672 ? 162.779 150.507 122.077 1.00 111.76 ? 698 MET   A SD  1 
ATOM   5474 C CE  . MET   A 1 672 ? 163.418 148.960 122.716 1.00 100.02 ? 698 MET   A CE  1 
ATOM   5475 N N   . THR   A 1 673 ? 158.202 147.865 120.056 1.00 80.60  ? 699 THR   A N   1 
ATOM   5476 C CA  . THR   A 1 673 ? 157.622 146.642 119.511 1.00 78.09  ? 699 THR   A CA  1 
ATOM   5477 C C   . THR   A 1 673 ? 157.835 146.559 118.005 1.00 81.83  ? 699 THR   A C   1 
ATOM   5478 O O   . THR   A 1 673 ? 158.137 145.484 117.473 1.00 83.79  ? 699 THR   A O   1 
ATOM   5479 C CB  . THR   A 1 673 ? 156.132 146.568 119.842 1.00 79.05  ? 699 THR   A CB  1 
ATOM   5480 O OG1 . THR   A 1 673 ? 155.950 146.636 121.261 1.00 86.67  ? 699 THR   A OG1 1 
ATOM   5481 C CG2 . THR   A 1 673 ? 155.536 145.273 119.323 1.00 74.84  ? 699 THR   A CG2 1 
ATOM   5482 N N   . CYS   A 1 674 ? 157.677 147.684 117.301 1.00 87.59  ? 700 CYS   A N   1 
ATOM   5483 C CA  . CYS   A 1 674 ? 157.895 147.681 115.857 1.00 86.17  ? 700 CYS   A CA  1 
ATOM   5484 C C   . CYS   A 1 674 ? 159.340 147.340 115.514 1.00 82.55  ? 700 CYS   A C   1 
ATOM   5485 O O   . CYS   A 1 674 ? 159.598 146.553 114.592 1.00 85.66  ? 700 CYS   A O   1 
ATOM   5486 C CB  . CYS   A 1 674 ? 157.512 149.036 115.264 1.00 85.40  ? 700 CYS   A CB  1 
ATOM   5487 S SG  . CYS   A 1 674 ? 155.735 149.315 115.136 1.00 96.95  ? 700 CYS   A SG  1 
ATOM   5488 N N   . ILE   A 1 675 ? 160.295 147.919 116.246 1.00 80.25  ? 701 ILE   A N   1 
ATOM   5489 C CA  . ILE   A 1 675 ? 161.705 147.628 115.985 1.00 82.12  ? 701 ILE   A CA  1 
ATOM   5490 C C   . ILE   A 1 675 ? 161.991 146.152 116.231 1.00 86.70  ? 701 ILE   A C   1 
ATOM   5491 O O   . ILE   A 1 675 ? 162.690 145.496 115.444 1.00 90.90  ? 701 ILE   A O   1 
ATOM   5492 C CB  . ILE   A 1 675 ? 162.611 148.531 116.845 1.00 84.68  ? 701 ILE   A CB  1 
ATOM   5493 C CG1 . ILE   A 1 675 ? 162.483 149.996 116.409 1.00 91.63  ? 701 ILE   A CG1 1 
ATOM   5494 C CG2 . ILE   A 1 675 ? 164.066 148.070 116.750 1.00 83.89  ? 701 ILE   A CG2 1 
ATOM   5495 C CD1 . ILE   A 1 675 ? 163.021 150.997 117.418 1.00 94.70  ? 701 ILE   A CD1 1 
ATOM   5496 N N   . SER   A 1 676 ? 161.449 145.606 117.322 1.00 87.90  ? 702 SER   A N   1 
ATOM   5497 C CA  . SER   A 1 676 ? 161.666 144.197 117.633 1.00 84.90  ? 702 SER   A CA  1 
ATOM   5498 C C   . SER   A 1 676 ? 161.087 143.293 116.551 1.00 83.74  ? 702 SER   A C   1 
ATOM   5499 O O   . SER   A 1 676 ? 161.727 142.319 116.139 1.00 83.78  ? 702 SER   A O   1 
ATOM   5500 C CB  . SER   A 1 676 ? 161.051 143.865 118.990 1.00 85.37  ? 702 SER   A CB  1 
ATOM   5501 O OG  . SER   A 1 676 ? 160.802 142.477 119.109 1.00 86.27  ? 702 SER   A OG  1 
ATOM   5502 N N   . LEU   A 1 677 ? 159.872 143.590 116.088 1.00 82.74  ? 703 LEU   A N   1 
ATOM   5503 C CA  . LEU   A 1 677 ? 159.255 142.758 115.060 1.00 82.03  ? 703 LEU   A CA  1 
ATOM   5504 C C   . LEU   A 1 677 ? 160.034 142.827 113.752 1.00 84.34  ? 703 LEU   A C   1 
ATOM   5505 O O   . LEU   A 1 677 ? 160.205 141.807 113.069 1.00 89.39  ? 703 LEU   A O   1 
ATOM   5506 C CB  . LEU   A 1 677 ? 157.802 143.179 114.844 1.00 84.53  ? 703 LEU   A CB  1 
ATOM   5507 C CG  . LEU   A 1 677 ? 156.833 142.879 115.991 1.00 84.54  ? 703 LEU   A CG  1 
ATOM   5508 C CD1 . LEU   A 1 677 ? 155.495 143.556 115.747 1.00 80.39  ? 703 LEU   A CD1 1 
ATOM   5509 C CD2 . LEU   A 1 677 ? 156.642 141.382 116.172 1.00 80.72  ? 703 LEU   A CD2 1 
ATOM   5510 N N   . ARG   A 1 678 ? 160.505 144.021 113.378 1.00 85.38  ? 704 ARG   A N   1 
ATOM   5511 C CA  . ARG   A 1 678 ? 161.320 144.136 112.172 1.00 86.93  ? 704 ARG   A CA  1 
ATOM   5512 C C   . ARG   A 1 678 ? 162.589 143.303 112.296 1.00 83.92  ? 704 ARG   A C   1 
ATOM   5513 O O   . ARG   A 1 678 ? 162.964 142.585 111.358 1.00 80.72  ? 704 ARG   A O   1 
ATOM   5514 C CB  . ARG   A 1 678 ? 161.665 145.602 111.910 1.00 97.18  ? 704 ARG   A CB  1 
ATOM   5515 C CG  . ARG   A 1 678 ? 162.343 145.872 110.562 1.00 101.62 ? 704 ARG   A CG  1 
ATOM   5516 C CD  . ARG   A 1 678 ? 163.127 147.176 110.573 1.00 109.74 ? 704 ARG   A CD  1 
ATOM   5517 N NE  . ARG   A 1 678 ? 164.255 147.129 111.498 1.00 108.94 ? 704 ARG   A NE  1 
ATOM   5518 C CZ  . ARG   A 1 678 ? 165.183 148.070 111.614 1.00 118.32 ? 704 ARG   A CZ  1 
ATOM   5519 N NH1 . ARG   A 1 678 ? 165.181 149.150 110.847 1.00 122.25 ? 704 ARG   A NH1 1 
ATOM   5520 N NH2 . ARG   A 1 678 ? 166.147 147.920 112.518 1.00 117.45 ? 704 ARG   A NH2 1 
ATOM   5521 N N   . ASN   A 1 679 ? 163.255 143.378 113.453 1.00 90.73  ? 705 ASN   A N   1 
ATOM   5522 C CA  . ASN   A 1 679 ? 164.461 142.583 113.665 1.00 91.33  ? 705 ASN   A CA  1 
ATOM   5523 C C   . ASN   A 1 679 ? 164.159 141.094 113.576 1.00 86.35  ? 705 ASN   A C   1 
ATOM   5524 O O   . ASN   A 1 679 ? 164.941 140.325 113.006 1.00 82.02  ? 705 ASN   A O   1 
ATOM   5525 C CB  . ASN   A 1 679 ? 165.081 142.918 115.020 1.00 91.98  ? 705 ASN   A CB  1 
ATOM   5526 C CG  . ASN   A 1 679 ? 165.630 144.326 115.077 1.00 103.23 ? 705 ASN   A CG  1 
ATOM   5527 O OD1 . ASN   A 1 679 ? 165.222 145.195 114.307 1.00 109.82 ? 705 ASN   A OD1 1 
ATOM   5528 N ND2 . ASN   A 1 679 ? 166.564 144.559 115.989 1.00 102.21 ? 705 ASN   A ND2 1 
ATOM   5529 N N   . LEU   A 1 680 ? 163.029 140.668 114.141 1.00 87.15  ? 706 LEU   A N   1 
ATOM   5530 C CA  . LEU   A 1 680 ? 162.687 139.250 114.132 1.00 76.35  ? 706 LEU   A CA  1 
ATOM   5531 C C   . LEU   A 1 680 ? 162.411 138.759 112.717 1.00 74.17  ? 706 LEU   A C   1 
ATOM   5532 O O   . LEU   A 1 680 ? 162.839 137.661 112.345 1.00 76.11  ? 706 LEU   A O   1 
ATOM   5533 C CB  . LEU   A 1 680 ? 161.477 138.999 115.033 1.00 75.08  ? 706 LEU   A CB  1 
ATOM   5534 C CG  . LEU   A 1 680 ? 161.402 137.647 115.746 1.00 77.62  ? 706 LEU   A CG  1 
ATOM   5535 C CD1 . LEU   A 1 680 ? 160.203 137.610 116.684 1.00 78.12  ? 706 LEU   A CD1 1 
ATOM   5536 C CD2 . LEU   A 1 680 ? 161.338 136.493 114.760 1.00 80.40  ? 706 LEU   A CD2 1 
ATOM   5537 N N   . ILE   A 1 681 ? 161.709 139.554 111.911 1.00 76.83  ? 707 ILE   A N   1 
ATOM   5538 C CA  . ILE   A 1 681 ? 161.281 139.078 110.597 1.00 75.04  ? 707 ILE   A CA  1 
ATOM   5539 C C   . ILE   A 1 681 ? 162.411 139.200 109.580 1.00 76.30  ? 707 ILE   A C   1 
ATOM   5540 O O   . ILE   A 1 681 ? 162.855 138.199 109.005 1.00 70.36  ? 707 ILE   A O   1 
ATOM   5541 C CB  . ILE   A 1 681 ? 160.019 139.830 110.132 1.00 77.29  ? 707 ILE   A CB  1 
ATOM   5542 C CG1 . ILE   A 1 681 ? 158.821 139.453 111.011 1.00 79.79  ? 707 ILE   A CG1 1 
ATOM   5543 C CG2 . ILE   A 1 681 ? 159.721 139.515 108.661 1.00 75.76  ? 707 ILE   A CG2 1 
ATOM   5544 C CD1 . ILE   A 1 681 ? 157.632 140.390 110.888 1.00 80.93  ? 707 ILE   A CD1 1 
ATOM   5545 N N   . LEU   A 1 682 ? 162.897 140.419 109.344 1.00 84.15  ? 708 LEU   A N   1 
ATOM   5546 C CA  . LEU   A 1 682 ? 163.819 140.667 108.239 1.00 80.44  ? 708 LEU   A CA  1 
ATOM   5547 C C   . LEU   A 1 682 ? 165.288 140.569 108.632 1.00 84.64  ? 708 LEU   A C   1 
ATOM   5548 O O   . LEU   A 1 682 ? 166.152 140.739 107.765 1.00 91.31  ? 708 LEU   A O   1 
ATOM   5549 C CB  . LEU   A 1 682 ? 163.560 142.050 107.631 1.00 81.47  ? 708 LEU   A CB  1 
ATOM   5550 C CG  . LEU   A 1 682 ? 162.233 142.234 106.897 1.00 79.43  ? 708 LEU   A CG  1 
ATOM   5551 C CD1 . LEU   A 1 682 ? 161.175 142.810 107.823 1.00 83.37  ? 708 LEU   A CD1 1 
ATOM   5552 C CD2 . LEU   A 1 682 ? 162.421 143.119 105.679 1.00 79.29  ? 708 LEU   A CD2 1 
ATOM   5553 N N   . GLY   A 1 683 ? 165.598 140.301 109.894 1.00 86.72  ? 709 GLY   A N   1 
ATOM   5554 C CA  . GLY   A 1 683 ? 166.971 140.275 110.357 1.00 87.08  ? 709 GLY   A CA  1 
ATOM   5555 C C   . GLY   A 1 683 ? 167.406 141.620 110.900 1.00 92.07  ? 709 GLY   A C   1 
ATOM   5556 O O   . GLY   A 1 683 ? 166.622 142.562 111.035 1.00 99.08  ? 709 GLY   A O   1 
ATOM   5557 N N   . ARG   A 1 684 ? 168.701 141.701 111.210 1.00 95.14  ? 710 ARG   A N   1 
ATOM   5558 C CA  . ARG   A 1 684 ? 169.264 142.855 111.898 1.00 107.70 ? 710 ARG   A CA  1 
ATOM   5559 C C   . ARG   A 1 684 ? 169.947 143.783 110.903 1.00 106.62 ? 710 ARG   A C   1 
ATOM   5560 O O   . ARG   A 1 684 ? 170.911 143.354 110.249 1.00 110.34 ? 710 ARG   A O   1 
ATOM   5561 C CB  . ARG   A 1 684 ? 170.260 142.394 112.954 1.00 117.57 ? 710 ARG   A CB  1 
ATOM   5562 C CG  . ARG   A 1 684 ? 170.680 143.483 113.922 1.00 120.66 ? 710 ARG   A CG  1 
ATOM   5563 C CD  . ARG   A 1 684 ? 171.432 142.920 115.120 1.00 123.46 ? 710 ARG   A CD  1 
ATOM   5564 N NE  . ARG   A 1 684 ? 170.576 142.101 115.971 1.00 125.25 ? 710 ARG   A NE  1 
ATOM   5565 C CZ  . ARG   A 1 684 ? 170.965 141.500 117.089 1.00 128.70 ? 710 ARG   A CZ  1 
ATOM   5566 N NH1 . ARG   A 1 684 ? 172.207 141.602 117.539 1.00 130.24 ? 710 ARG   A NH1 1 
ATOM   5567 N NH2 . ARG   A 1 684 ? 170.085 140.776 117.775 1.00 127.49 ? 710 ARG   A NH2 1 
ATOM   5568 N N   . PRO   A 1 685 ? 169.506 145.047 110.738 1.00 105.53 ? 711 PRO   A N   1 
ATOM   5569 C CA  . PRO   A 1 685 ? 170.296 145.996 109.939 1.00 108.70 ? 711 PRO   A CA  1 
ATOM   5570 C C   . PRO   A 1 685 ? 171.543 146.489 110.657 1.00 117.15 ? 711 PRO   A C   1 
ATOM   5571 O O   . PRO   A 1 685 ? 171.905 145.977 111.721 1.00 121.89 ? 711 PRO   A O   1 
ATOM   5572 C CB  . PRO   A 1 685 ? 169.313 147.145 109.680 1.00 115.45 ? 711 PRO   A CB  1 
ATOM   5573 C CG  . PRO   A 1 685 ? 167.980 146.553 109.856 1.00 117.46 ? 711 PRO   A CG  1 
ATOM   5574 C CD  . PRO   A 1 685 ? 168.142 145.558 110.956 1.00 112.35 ? 711 PRO   A CD  1 
ATOM   5575 N N   . SER   A 1 686 ? 172.211 147.477 110.061 1.00 120.41 ? 712 SER   A N   1 
ATOM   5576 C CA  . SER   A 1 686 ? 173.483 147.968 110.575 1.00 121.20 ? 712 SER   A CA  1 
ATOM   5577 C C   . SER   A 1 686 ? 173.337 148.516 111.992 1.00 119.07 ? 712 SER   A C   1 
ATOM   5578 O O   . SER   A 1 686 ? 172.283 149.023 112.385 1.00 121.91 ? 712 SER   A O   1 
ATOM   5579 C CB  . SER   A 1 686 ? 174.039 149.057 109.656 1.00 123.39 ? 712 SER   A CB  1 
ATOM   5580 O OG  . SER   A 1 686 ? 174.210 148.572 108.336 1.00 125.16 ? 712 SER   A OG  1 
ATOM   5581 N N   . LEU   A 1 687 ? 174.424 148.402 112.760 1.00 116.64 ? 713 LEU   A N   1 
ATOM   5582 C CA  . LEU   A 1 687 ? 174.397 148.764 114.174 1.00 123.63 ? 713 LEU   A CA  1 
ATOM   5583 C C   . LEU   A 1 687 ? 174.105 150.248 114.368 1.00 127.19 ? 713 LEU   A C   1 
ATOM   5584 O O   . LEU   A 1 687 ? 173.364 150.629 115.284 1.00 129.51 ? 713 LEU   A O   1 
ATOM   5585 C CB  . LEU   A 1 687 ? 175.728 148.395 114.837 1.00 124.02 ? 713 LEU   A CB  1 
ATOM   5586 C CG  . LEU   A 1 687 ? 176.104 146.918 115.047 1.00 127.91 ? 713 LEU   A CG  1 
ATOM   5587 C CD1 . LEU   A 1 687 ? 175.030 146.174 115.832 1.00 128.57 ? 713 LEU   A CD1 1 
ATOM   5588 C CD2 . LEU   A 1 687 ? 176.399 146.200 113.733 1.00 123.88 ? 713 LEU   A CD2 1 
ATOM   5589 N N   . GLU   A 1 688 ? 174.693 151.103 113.528 1.00 126.25 ? 714 GLU   A N   1 
ATOM   5590 C CA  . GLU   A 1 688 ? 174.441 152.536 113.637 1.00 125.31 ? 714 GLU   A CA  1 
ATOM   5591 C C   . GLU   A 1 688 ? 172.972 152.849 113.391 1.00 126.40 ? 714 GLU   A C   1 
ATOM   5592 O O   . GLU   A 1 688 ? 172.396 153.725 114.048 1.00 125.27 ? 714 GLU   A O   1 
ATOM   5593 C CB  . GLU   A 1 688 ? 175.336 153.296 112.656 1.00 130.28 ? 714 GLU   A CB  1 
ATOM   5594 C CG  . GLU   A 1 688 ? 175.243 154.824 112.752 1.00 132.76 ? 714 GLU   A CG  1 
ATOM   5595 C CD  . GLU   A 1 688 ? 174.179 155.444 111.851 1.00 137.66 ? 714 GLU   A CD  1 
ATOM   5596 O OE1 . GLU   A 1 688 ? 173.487 154.707 111.116 1.00 138.53 ? 714 GLU   A OE1 1 
ATOM   5597 O OE2 . GLU   A 1 688 ? 174.037 156.684 111.880 1.00 136.22 ? 714 GLU   A OE2 1 
ATOM   5598 N N   . GLN   A 1 689 ? 172.350 152.146 112.442 1.00 126.98 ? 715 GLN   A N   1 
ATOM   5599 C CA  . GLN   A 1 689 ? 170.918 152.311 112.220 1.00 128.37 ? 715 GLN   A CA  1 
ATOM   5600 C C   . GLN   A 1 689 ? 170.129 151.929 113.466 1.00 126.82 ? 715 GLN   A C   1 
ATOM   5601 O O   . GLN   A 1 689 ? 169.157 152.604 113.823 1.00 124.65 ? 715 GLN   A O   1 
ATOM   5602 C CB  . GLN   A 1 689 ? 170.475 151.471 111.022 1.00 128.69 ? 715 GLN   A CB  1 
ATOM   5603 C CG  . GLN   A 1 689 ? 169.028 151.694 110.599 1.00 133.24 ? 715 GLN   A CG  1 
ATOM   5604 C CD  . GLN   A 1 689 ? 168.659 150.914 109.352 1.00 134.27 ? 715 GLN   A CD  1 
ATOM   5605 O OE1 . GLN   A 1 689 ? 169.511 150.288 108.721 1.00 133.02 ? 715 GLN   A OE1 1 
ATOM   5606 N NE2 . GLN   A 1 689 ? 167.381 150.947 108.991 1.00 129.86 ? 715 GLN   A NE2 1 
ATOM   5607 N N   . LEU   A 1 690 ? 170.531 150.848 114.139 1.00 125.76 ? 716 LEU   A N   1 
ATOM   5608 C CA  . LEU   A 1 690 ? 169.855 150.456 115.371 1.00 119.60 ? 716 LEU   A CA  1 
ATOM   5609 C C   . LEU   A 1 690 ? 169.998 151.528 116.440 1.00 116.64 ? 716 LEU   A C   1 
ATOM   5610 O O   . LEU   A 1 690 ? 169.036 151.833 117.154 1.00 120.87 ? 716 LEU   A O   1 
ATOM   5611 C CB  . LEU   A 1 690 ? 170.412 149.128 115.883 1.00 121.47 ? 716 LEU   A CB  1 
ATOM   5612 C CG  . LEU   A 1 690 ? 170.248 147.896 114.991 1.00 124.46 ? 716 LEU   A CG  1 
ATOM   5613 C CD1 . LEU   A 1 690 ? 170.906 146.693 115.645 1.00 123.09 ? 716 LEU   A CD1 1 
ATOM   5614 C CD2 . LEU   A 1 690 ? 168.781 147.608 114.703 1.00 120.96 ? 716 LEU   A CD2 1 
ATOM   5615 N N   . ALA   A 1 691 ? 171.195 152.101 116.577 1.00 115.64 ? 717 ALA   A N   1 
ATOM   5616 C CA  . ALA   A 1 691 ? 171.392 153.156 117.566 1.00 120.17 ? 717 ALA   A CA  1 
ATOM   5617 C C   . ALA   A 1 691 ? 170.528 154.369 117.250 1.00 122.53 ? 717 ALA   A C   1 
ATOM   5618 O O   . ALA   A 1 691 ? 169.907 154.954 118.147 1.00 121.03 ? 717 ALA   A O   1 
ATOM   5619 C CB  . ALA   A 1 691 ? 172.868 153.549 117.628 1.00 121.88 ? 717 ALA   A CB  1 
ATOM   5620 N N   . GLN   A 1 692 ? 170.466 154.753 115.973 1.00 124.25 ? 718 GLN   A N   1 
ATOM   5621 C CA  . GLN   A 1 692 ? 169.634 155.885 115.577 1.00 123.60 ? 718 GLN   A CA  1 
ATOM   5622 C C   . GLN   A 1 692 ? 168.162 155.609 115.854 1.00 124.18 ? 718 GLN   A C   1 
ATOM   5623 O O   . GLN   A 1 692 ? 167.439 156.486 116.336 1.00 123.93 ? 718 GLN   A O   1 
ATOM   5624 C CB  . GLN   A 1 692 ? 169.862 156.202 114.096 1.00 125.05 ? 718 GLN   A CB  1 
ATOM   5625 C CG  . GLN   A 1 692 ? 168.984 157.313 113.517 1.00 124.84 ? 718 GLN   A CG  1 
ATOM   5626 C CD  . GLN   A 1 692 ? 169.086 158.614 114.289 1.00 127.59 ? 718 GLN   A CD  1 
ATOM   5627 O OE1 . GLN   A 1 692 ? 170.084 158.876 114.960 1.00 127.75 ? 718 GLN   A OE1 1 
ATOM   5628 N NE2 . GLN   A 1 692 ? 168.049 159.439 114.196 1.00 127.89 ? 718 GLN   A NE2 1 
ATOM   5629 N N   . GLU   A 1 693 ? 167.697 154.395 115.548 1.00 124.96 ? 719 GLU   A N   1 
ATOM   5630 C CA  . GLU   A 1 693 ? 166.299 154.053 115.793 1.00 122.52 ? 719 GLU   A CA  1 
ATOM   5631 C C   . GLU   A 1 693 ? 165.979 154.049 117.281 1.00 118.04 ? 719 GLU   A C   1 
ATOM   5632 O O   . GLU   A 1 693 ? 164.906 154.505 117.692 1.00 115.04 ? 719 GLU   A O   1 
ATOM   5633 C CB  . GLU   A 1 693 ? 165.977 152.697 115.171 1.00 124.23 ? 719 GLU   A CB  1 
ATOM   5634 C CG  . GLU   A 1 693 ? 165.895 152.728 113.658 1.00 129.47 ? 719 GLU   A CG  1 
ATOM   5635 C CD  . GLU   A 1 693 ? 165.638 151.361 113.061 1.00 134.45 ? 719 GLU   A CD  1 
ATOM   5636 O OE1 . GLU   A 1 693 ? 165.540 150.383 113.831 1.00 135.64 ? 719 GLU   A OE1 1 
ATOM   5637 O OE2 . GLU   A 1 693 ? 165.533 151.265 111.820 1.00 132.73 ? 719 GLU   A OE2 1 
ATOM   5638 N N   . VAL   A 1 694 ? 166.887 153.521 118.104 1.00 118.15 ? 720 VAL   A N   1 
ATOM   5639 C CA  . VAL   A 1 694 ? 166.664 153.525 119.547 1.00 113.54 ? 720 VAL   A CA  1 
ATOM   5640 C C   . VAL   A 1 694 ? 166.609 154.954 120.066 1.00 112.20 ? 720 VAL   A C   1 
ATOM   5641 O O   . VAL   A 1 694 ? 165.786 155.285 120.927 1.00 113.80 ? 720 VAL   A O   1 
ATOM   5642 C CB  . VAL   A 1 694 ? 167.750 152.697 120.261 1.00 116.47 ? 720 VAL   A CB  1 
ATOM   5643 C CG1 . VAL   A 1 694 ? 167.688 152.908 121.768 1.00 116.01 ? 720 VAL   A CG1 1 
ATOM   5644 C CG2 . VAL   A 1 694 ? 167.590 151.218 119.938 1.00 117.49 ? 720 VAL   A CG2 1 
ATOM   5645 N N   . THR   A 1 695 ? 167.489 155.822 119.558 1.00 115.51 ? 721 THR   A N   1 
ATOM   5646 C CA  . THR   A 1 695 ? 167.432 157.231 119.935 1.00 119.94 ? 721 THR   A CA  1 
ATOM   5647 C C   . THR   A 1 695 ? 166.108 157.858 119.517 1.00 118.69 ? 721 THR   A C   1 
ATOM   5648 O O   . THR   A 1 695 ? 165.525 158.656 120.260 1.00 119.03 ? 721 THR   A O   1 
ATOM   5649 C CB  . THR   A 1 695 ? 168.603 157.989 119.308 1.00 122.81 ? 721 THR   A CB  1 
ATOM   5650 O OG1 . THR   A 1 695 ? 169.840 157.397 119.725 1.00 121.88 ? 721 THR   A OG1 1 
ATOM   5651 C CG2 . THR   A 1 695 ? 168.581 159.455 119.724 1.00 119.46 ? 721 THR   A CG2 1 
ATOM   5652 N N   . TYR   A 1 696 ? 165.625 157.514 118.322 1.00 115.65 ? 722 TYR   A N   1 
ATOM   5653 C CA  . TYR   A 1 696 ? 164.368 158.068 117.832 1.00 113.72 ? 722 TYR   A CA  1 
ATOM   5654 C C   . TYR   A 1 696 ? 163.190 157.622 118.690 1.00 114.73 ? 722 TYR   A C   1 
ATOM   5655 O O   . TYR   A 1 696 ? 162.289 158.417 118.982 1.00 117.03 ? 722 TYR   A O   1 
ATOM   5656 C CB  . TYR   A 1 696 ? 164.162 157.653 116.375 1.00 114.13 ? 722 TYR   A CB  1 
ATOM   5657 C CG  . TYR   A 1 696 ? 162.856 158.109 115.768 1.00 114.16 ? 722 TYR   A CG  1 
ATOM   5658 C CD1 . TYR   A 1 696 ? 162.632 159.448 115.476 1.00 117.42 ? 722 TYR   A CD1 1 
ATOM   5659 C CD2 . TYR   A 1 696 ? 161.855 157.198 115.467 1.00 113.09 ? 722 TYR   A CD2 1 
ATOM   5660 C CE1 . TYR   A 1 696 ? 161.440 159.866 114.914 1.00 120.31 ? 722 TYR   A CE1 1 
ATOM   5661 C CE2 . TYR   A 1 696 ? 160.663 157.605 114.905 1.00 112.99 ? 722 TYR   A CE2 1 
ATOM   5662 C CZ  . TYR   A 1 696 ? 160.460 158.940 114.629 1.00 118.61 ? 722 TYR   A CZ  1 
ATOM   5663 O OH  . TYR   A 1 696 ? 159.272 159.349 114.069 1.00 118.48 ? 722 TYR   A OH  1 
ATOM   5664 N N   . ALA   A 1 697 ? 163.176 156.351 119.097 1.00 110.48 ? 723 ALA   A N   1 
ATOM   5665 C CA  . ALA   A 1 697 ? 162.055 155.833 119.876 1.00 105.18 ? 723 ALA   A CA  1 
ATOM   5666 C C   . ALA   A 1 697 ? 161.957 156.512 121.237 1.00 104.68 ? 723 ALA   A C   1 
ATOM   5667 O O   . ALA   A 1 697 ? 160.858 156.861 121.684 1.00 105.20 ? 723 ALA   A O   1 
ATOM   5668 C CB  . ALA   A 1 697 ? 162.193 154.321 120.045 1.00 105.36 ? 723 ALA   A CB  1 
ATOM   5669 N N   . ASN   A 1 698 ? 163.091 156.708 121.909 1.00 105.56 ? 724 ASN   A N   1 
ATOM   5670 C CA  . ASN   A 1 698 ? 163.094 157.288 123.248 1.00 105.69 ? 724 ASN   A CA  1 
ATOM   5671 C C   . ASN   A 1 698 ? 162.811 158.785 123.258 1.00 111.09 ? 724 ASN   A C   1 
ATOM   5672 O O   . ASN   A 1 698 ? 162.686 159.358 124.346 1.00 114.53 ? 724 ASN   A O   1 
ATOM   5673 C CB  . ASN   A 1 698 ? 164.438 157.018 123.926 1.00 105.34 ? 724 ASN   A CB  1 
ATOM   5674 C CG  . ASN   A 1 698 ? 164.674 155.544 124.188 1.00 108.07 ? 724 ASN   A CG  1 
ATOM   5675 O OD1 . ASN   A 1 698 ? 163.733 154.786 124.426 1.00 109.35 ? 724 ASN   A OD1 1 
ATOM   5676 N ND2 . ASN   A 1 698 ? 165.933 155.130 124.147 1.00 108.23 ? 724 ASN   A ND2 1 
ATOM   5677 N N   . LEU   A 1 699 ? 162.726 159.431 122.096 1.00 113.39 ? 725 LEU   A N   1 
ATOM   5678 C CA  . LEU   A 1 699 ? 162.546 160.875 122.045 1.00 115.36 ? 725 LEU   A CA  1 
ATOM   5679 C C   . LEU   A 1 699 ? 161.241 161.293 122.715 1.00 112.20 ? 725 LEU   A C   1 
ATOM   5680 O O   . LEU   A 1 699 ? 160.188 160.687 122.501 1.00 112.83 ? 725 LEU   A O   1 
ATOM   5681 C CB  . LEU   A 1 699 ? 162.568 161.351 120.590 1.00 119.51 ? 725 LEU   A CB  1 
ATOM   5682 C CG  . LEU   A 1 699 ? 162.414 162.853 120.324 1.00 124.56 ? 725 LEU   A CG  1 
ATOM   5683 C CD1 . LEU   A 1 699 ? 163.518 163.651 121.002 1.00 121.63 ? 725 LEU   A CD1 1 
ATOM   5684 C CD2 . LEU   A 1 699 ? 162.403 163.123 118.827 1.00 120.38 ? 725 LEU   A CD2 1 
ATOM   5685 N N   . ARG   A 1 700 ? 161.323 162.337 123.532 1.00 107.23 ? 726 ARG   A N   1 
ATOM   5686 C CA  . ARG   A 1 700 ? 160.139 162.874 124.182 1.00 112.34 ? 726 ARG   A CA  1 
ATOM   5687 C C   . ARG   A 1 700 ? 159.217 163.495 123.129 1.00 119.02 ? 726 ARG   A C   1 
ATOM   5688 O O   . ARG   A 1 700 ? 159.706 164.083 122.159 1.00 119.43 ? 726 ARG   A O   1 
ATOM   5689 C CB  . ARG   A 1 700 ? 160.550 163.917 125.221 1.00 114.15 ? 726 ARG   A CB  1 
ATOM   5690 C CG  . ARG   A 1 700 ? 159.478 164.315 126.227 1.00 118.47 ? 726 ARG   A CG  1 
ATOM   5691 C CD  . ARG   A 1 700 ? 159.132 163.173 127.174 1.00 120.84 ? 726 ARG   A CD  1 
ATOM   5692 N NE  . ARG   A 1 700 ? 158.264 163.604 128.265 1.00 128.07 ? 726 ARG   A NE  1 
ATOM   5693 C CZ  . ARG   A 1 700 ? 157.900 162.845 129.292 1.00 128.88 ? 726 ARG   A CZ  1 
ATOM   5694 N NH1 . ARG   A 1 700 ? 158.314 161.592 129.415 1.00 125.45 ? 726 ARG   A NH1 1 
ATOM   5695 N NH2 . ARG   A 1 700 ? 157.101 163.356 130.223 1.00 128.26 ? 726 ARG   A NH2 1 
ATOM   5696 N N   . PRO   A 1 701 ? 157.866 163.375 123.273 1.00 119.99 ? 727 PRO   A N   1 
ATOM   5697 C CA  . PRO   A 1 701 ? 156.985 163.866 122.199 1.00 117.56 ? 727 PRO   A CA  1 
ATOM   5698 C C   . PRO   A 1 701 ? 157.108 165.359 121.930 1.00 117.71 ? 727 PRO   A C   1 
ATOM   5699 O O   . PRO   A 1 701 ? 157.369 165.762 120.793 1.00 115.90 ? 727 PRO   A O   1 
ATOM   5700 C CB  . PRO   A 1 701 ? 155.578 163.510 122.703 1.00 112.59 ? 727 PRO   A CB  1 
ATOM   5701 C CG  . PRO   A 1 701 ? 155.778 162.422 123.664 1.00 112.88 ? 727 PRO   A CG  1 
ATOM   5702 C CD  . PRO   A 1 701 ? 157.080 162.710 124.332 1.00 115.48 ? 727 PRO   A CD  1 
ATOM   5703 N N   . PHE   A 1 702 ? 156.949 166.178 122.967 1.00 119.61 ? 728 PHE   A N   1 
ATOM   5704 C CA  . PHE   A 1 702 ? 156.916 167.634 122.824 1.00 120.66 ? 728 PHE   A CA  1 
ATOM   5705 C C   . PHE   A 1 702 ? 155.902 168.074 121.770 1.00 117.78 ? 728 PHE   A C   1 
ATOM   5706 O O   . PHE   A 1 702 ? 154.929 167.371 121.497 1.00 112.07 ? 728 PHE   A O   1 
ATOM   5707 C CB  . PHE   A 1 702 ? 158.303 168.181 122.474 1.00 120.28 ? 728 PHE   A CB  1 
ATOM   5708 C CG  . PHE   A 1 702 ? 159.195 168.369 123.666 1.00 126.58 ? 728 PHE   A CG  1 
ATOM   5709 C CD1 . PHE   A 1 702 ? 159.134 169.533 124.414 1.00 129.00 ? 728 PHE   A CD1 1 
ATOM   5710 C CD2 . PHE   A 1 702 ? 160.094 167.386 124.039 1.00 124.99 ? 728 PHE   A CD2 1 
ATOM   5711 C CE1 . PHE   A 1 702 ? 159.952 169.712 125.513 1.00 127.46 ? 728 PHE   A CE1 1 
ATOM   5712 C CE2 . PHE   A 1 702 ? 160.916 167.560 125.137 1.00 125.91 ? 728 PHE   A CE2 1 
ATOM   5713 C CZ  . PHE   A 1 702 ? 160.844 168.724 125.875 1.00 125.32 ? 728 PHE   A CZ  1 
ATOM   5714 N N   . THR   B 2 1   ? 180.650 147.186 142.556 1.00 62.69  ? 29  THR   P N   1 
ATOM   5715 C CA  . THR   B 2 1   ? 180.000 147.201 143.861 1.00 64.13  ? 29  THR   P CA  1 
ATOM   5716 C C   . THR   B 2 1   ? 179.444 145.830 144.239 1.00 62.23  ? 29  THR   P C   1 
ATOM   5717 O O   . THR   B 2 1   ? 178.575 145.727 145.103 1.00 65.89  ? 29  THR   P O   1 
ATOM   5718 C CB  . THR   B 2 1   ? 178.850 148.223 143.899 1.00 69.54  ? 29  THR   P CB  1 
ATOM   5719 O OG1 . THR   B 2 1   ? 177.861 147.870 142.923 1.00 69.88  ? 29  THR   P OG1 1 
ATOM   5720 C CG2 . THR   B 2 1   ? 179.367 149.624 143.611 1.00 69.25  ? 29  THR   P CG2 1 
ATOM   5721 N N   . VAL   B 2 2   ? 179.941 144.776 143.587 1.00 55.42  ? 30  VAL   P N   1 
ATOM   5722 C CA  . VAL   B 2 2   ? 179.480 143.429 143.905 1.00 53.21  ? 30  VAL   P CA  1 
ATOM   5723 C C   . VAL   B 2 2   ? 179.885 143.051 145.324 1.00 58.16  ? 30  VAL   P C   1 
ATOM   5724 O O   . VAL   B 2 2   ? 179.083 142.499 146.089 1.00 60.75  ? 30  VAL   P O   1 
ATOM   5725 C CB  . VAL   B 2 2   ? 180.019 142.423 142.872 1.00 54.20  ? 30  VAL   P CB  1 
ATOM   5726 C CG1 . VAL   B 2 2   ? 179.559 141.011 143.213 1.00 56.58  ? 30  VAL   P CG1 1 
ATOM   5727 C CG2 . VAL   B 2 2   ? 179.578 142.813 141.464 1.00 58.62  ? 30  VAL   P CG2 1 
ATOM   5728 N N   . PHE   B 2 3   ? 181.128 143.347 145.698 1.00 57.21  ? 31  PHE   P N   1 
ATOM   5729 C CA  . PHE   B 2 3   ? 181.670 143.027 147.013 1.00 51.35  ? 31  PHE   P CA  1 
ATOM   5730 C C   . PHE   B 2 3   ? 181.729 144.293 147.855 1.00 51.47  ? 31  PHE   P C   1 
ATOM   5731 O O   . PHE   B 2 3   ? 182.200 145.333 147.384 1.00 57.14  ? 31  PHE   P O   1 
ATOM   5732 C CB  . PHE   B 2 3   ? 183.066 142.416 146.893 1.00 51.31  ? 31  PHE   P CB  1 
ATOM   5733 C CG  . PHE   B 2 3   ? 183.113 141.156 146.082 1.00 50.98  ? 31  PHE   P CG  1 
ATOM   5734 C CD1 . PHE   B 2 3   ? 183.271 141.203 144.711 1.00 52.47  ? 31  PHE   P CD1 1 
ATOM   5735 C CD2 . PHE   B 2 3   ? 183.012 139.921 146.695 1.00 53.42  ? 31  PHE   P CD2 1 
ATOM   5736 C CE1 . PHE   B 2 3   ? 183.317 140.043 143.965 1.00 56.36  ? 31  PHE   P CE1 1 
ATOM   5737 C CE2 . PHE   B 2 3   ? 183.058 138.759 145.956 1.00 55.01  ? 31  PHE   P CE2 1 
ATOM   5738 C CZ  . PHE   B 2 3   ? 183.211 138.820 144.589 1.00 56.50  ? 31  PHE   P CZ  1 
ATOM   5739 N N   . LEU   B 2 4   ? 181.259 144.198 149.097 1.00 49.18  ? 32  LEU   P N   1 
ATOM   5740 C CA  . LEU   B 2 4   ? 181.185 145.327 150.011 1.00 47.02  ? 32  LEU   P CA  1 
ATOM   5741 C C   . LEU   B 2 4   ? 182.195 145.148 151.138 1.00 49.74  ? 32  LEU   P C   1 
ATOM   5742 O O   . LEU   B 2 4   ? 182.557 144.025 151.499 1.00 53.06  ? 32  LEU   P O   1 
ATOM   5743 C CB  . LEU   B 2 4   ? 179.772 145.469 150.586 1.00 48.24  ? 32  LEU   P CB  1 
ATOM   5744 C CG  . LEU   B 2 4   ? 179.357 146.825 151.160 1.00 48.83  ? 32  LEU   P CG  1 
ATOM   5745 C CD1 . LEU   B 2 4   ? 179.343 147.905 150.088 1.00 49.98  ? 32  LEU   P CD1 1 
ATOM   5746 C CD2 . LEU   B 2 4   ? 177.990 146.716 151.812 1.00 49.63  ? 32  LEU   P CD2 1 
ATOM   5747 N N   . ASP   B 2 5   ? 182.646 146.271 151.685 1.00 51.90  ? 33  ASP   P N   1 
ATOM   5748 C CA  . ASP   B 2 5   ? 183.721 146.254 152.665 1.00 49.46  ? 33  ASP   P CA  1 
ATOM   5749 C C   . ASP   B 2 5   ? 183.255 145.639 153.980 1.00 52.36  ? 33  ASP   P C   1 
ATOM   5750 O O   . ASP   B 2 5   ? 182.064 145.632 154.306 1.00 55.57  ? 33  ASP   P O   1 
ATOM   5751 C CB  . ASP   B 2 5   ? 184.236 147.673 152.904 1.00 50.82  ? 33  ASP   P CB  1 
ATOM   5752 C CG  . ASP   B 2 5   ? 185.606 147.698 153.552 1.00 56.64  ? 33  ASP   P CG  1 
ATOM   5753 O OD1 . ASP   B 2 5   ? 186.086 146.630 153.985 1.00 59.54  ? 33  ASP   P OD1 1 
ATOM   5754 O OD2 . ASP   B 2 5   ? 186.208 148.790 153.621 1.00 58.55  ? 33  ASP   P OD2 1 
ATOM   5755 N N   . HIS   B 2 6   ? 184.220 145.109 154.736 1.00 53.33  ? 34  HIS   P N   1 
ATOM   5756 C CA  . HIS   B 2 6   ? 183.921 144.542 156.047 1.00 52.44  ? 34  HIS   P CA  1 
ATOM   5757 C C   . HIS   B 2 6   ? 183.355 145.595 156.991 1.00 49.35  ? 34  HIS   P C   1 
ATOM   5758 O O   . HIS   B 2 6   ? 182.404 145.329 157.734 1.00 46.68  ? 34  HIS   P O   1 
ATOM   5759 C CB  . HIS   B 2 6   ? 185.184 143.918 156.637 1.00 50.99  ? 34  HIS   P CB  1 
ATOM   5760 C CG  . HIS   B 2 6   ? 185.030 143.452 158.050 1.00 48.89  ? 34  HIS   P CG  1 
ATOM   5761 N ND1 . HIS   B 2 6   ? 183.862 142.901 158.531 1.00 54.67  ? 34  HIS   P ND1 1 
ATOM   5762 C CD2 . HIS   B 2 6   ? 185.903 143.443 159.085 1.00 51.29  ? 34  HIS   P CD2 1 
ATOM   5763 C CE1 . HIS   B 2 6   ? 184.019 142.580 159.803 1.00 57.20  ? 34  HIS   P CE1 1 
ATOM   5764 N NE2 . HIS   B 2 6   ? 185.249 142.898 160.163 1.00 57.81  ? 34  HIS   P NE2 1 
ATOM   5765 N N   . GLU   B 2 7   ? 183.937 146.794 156.985 1.00 52.70  ? 35  GLU   P N   1 
ATOM   5766 C CA  . GLU   B 2 7   ? 183.469 147.848 157.877 1.00 51.48  ? 35  GLU   P CA  1 
ATOM   5767 C C   . GLU   B 2 7   ? 182.066 148.309 157.504 1.00 48.47  ? 35  GLU   P C   1 
ATOM   5768 O O   . GLU   B 2 7   ? 181.216 148.499 158.381 1.00 51.61  ? 35  GLU   P O   1 
ATOM   5769 C CB  . GLU   B 2 7   ? 184.451 149.019 157.845 1.00 53.89  ? 35  GLU   P CB  1 
ATOM   5770 C CG  . GLU   B 2 7   ? 184.110 150.171 158.779 1.00 58.11  ? 35  GLU   P CG  1 
ATOM   5771 C CD  . GLU   B 2 7   ? 185.170 151.256 158.776 1.00 65.08  ? 35  GLU   P CD  1 
ATOM   5772 O OE1 . GLU   B 2 7   ? 186.338 150.950 158.458 1.00 64.53  ? 35  GLU   P OE1 1 
ATOM   5773 O OE2 . GLU   B 2 7   ? 184.833 152.417 159.087 1.00 69.59  ? 35  GLU   P OE2 1 
ATOM   5774 N N   . ASN   B 2 8   ? 181.801 148.494 156.211 1.00 51.14  ? 36  ASN   P N   1 
ATOM   5775 C CA  . ASN   B 2 8   ? 180.512 149.017 155.778 1.00 48.67  ? 36  ASN   P CA  1 
ATOM   5776 C C   . ASN   B 2 8   ? 179.394 147.988 155.858 1.00 45.00  ? 36  ASN   P C   1 
ATOM   5777 O O   . ASN   B 2 8   ? 178.224 148.375 155.932 1.00 46.77  ? 36  ASN   P O   1 
ATOM   5778 C CB  . ASN   B 2 8   ? 180.612 149.546 154.346 1.00 51.74  ? 36  ASN   P CB  1 
ATOM   5779 C CG  . ASN   B 2 8   ? 181.540 150.740 154.227 1.00 57.21  ? 36  ASN   P CG  1 
ATOM   5780 O OD1 . ASN   B 2 8   ? 181.787 151.448 155.203 1.00 56.23  ? 36  ASN   P OD1 1 
ATOM   5781 N ND2 . ASN   B 2 8   ? 182.058 150.971 153.026 1.00 55.51  ? 36  ASN   P ND2 1 
ATOM   5782 N N   . ALA   B 2 9   ? 179.718 146.696 155.832 1.00 44.45  ? 37  ALA   P N   1 
ATOM   5783 C CA  . ALA   B 2 9   ? 178.674 145.678 155.886 1.00 45.28  ? 37  ALA   P CA  1 
ATOM   5784 C C   . ALA   B 2 9   ? 177.946 145.695 157.224 1.00 47.98  ? 37  ALA   P C   1 
ATOM   5785 O O   . ALA   B 2 9   ? 176.718 145.561 157.269 1.00 52.63  ? 37  ALA   P O   1 
ATOM   5786 C CB  . ALA   B 2 9   ? 179.274 144.299 155.623 1.00 47.32  ? 37  ALA   P CB  1 
ATOM   5787 N N   . ASN   B 2 10  ? 178.681 145.864 158.322 1.00 48.87  ? 38  ASN   P N   1 
ATOM   5788 C CA  . ASN   B 2 10  ? 178.123 145.729 159.668 1.00 43.97  ? 38  ASN   P CA  1 
ATOM   5789 C C   . ASN   B 2 10  ? 177.726 147.097 160.220 1.00 47.13  ? 38  ASN   P C   1 
ATOM   5790 O O   . ASN   B 2 10  ? 178.261 147.576 161.217 1.00 54.87  ? 38  ASN   P O   1 
ATOM   5791 C CB  . ASN   B 2 10  ? 179.128 145.041 160.583 1.00 44.33  ? 38  ASN   P CB  1 
ATOM   5792 C CG  . ASN   B 2 10  ? 179.707 143.788 159.973 1.00 49.63  ? 38  ASN   P CG  1 
ATOM   5793 O OD1 . ASN   B 2 10  ? 179.125 143.204 159.061 1.00 55.42  ? 38  ASN   P OD1 1 
ATOM   5794 N ND2 . ASN   B 2 10  ? 180.860 143.364 160.473 1.00 50.14  ? 38  ASN   P ND2 1 
ATOM   5795 N N   . LYS   B 2 11  ? 176.747 147.715 159.559 1.00 48.65  ? 39  LYS   P N   1 
ATOM   5796 C CA  . LYS   B 2 11  ? 176.184 149.003 159.976 1.00 51.77  ? 39  LYS   P CA  1 
ATOM   5797 C C   . LYS   B 2 11  ? 174.679 148.820 160.130 1.00 57.31  ? 39  LYS   P C   1 
ATOM   5798 O O   . LYS   B 2 11  ? 173.915 149.046 159.188 1.00 62.22  ? 39  LYS   P O   1 
ATOM   5799 C CB  . LYS   B 2 11  ? 176.516 150.105 158.977 1.00 54.03  ? 39  LYS   P CB  1 
ATOM   5800 C CG  . LYS   B 2 11  ? 177.892 150.717 159.162 1.00 51.58  ? 39  LYS   P CG  1 
ATOM   5801 C CD  . LYS   B 2 11  ? 178.085 151.921 158.258 1.00 55.01  ? 39  LYS   P CD  1 
ATOM   5802 C CE  . LYS   B 2 11  ? 179.414 152.614 158.517 1.00 58.40  ? 39  LYS   P CE  1 
ATOM   5803 N NZ  . LYS   B 2 11  ? 180.587 151.779 158.141 1.00 60.21  ? 39  LYS   P NZ  1 
ATOM   5804 N N   . ILE   B 2 12  ? 174.254 148.408 161.325 1.00 58.74  ? 40  ILE   P N   1 
ATOM   5805 C CA  . ILE   B 2 12  ? 172.827 148.245 161.582 1.00 58.39  ? 40  ILE   P CA  1 
ATOM   5806 C C   . ILE   B 2 12  ? 172.144 149.604 161.628 1.00 62.88  ? 40  ILE   P C   1 
ATOM   5807 O O   . ILE   B 2 12  ? 171.043 149.781 161.094 1.00 66.77  ? 40  ILE   P O   1 
ATOM   5808 C CB  . ILE   B 2 12  ? 172.594 147.453 162.885 1.00 53.05  ? 40  ILE   P CB  1 
ATOM   5809 C CG1 . ILE   B 2 12  ? 173.436 146.168 162.928 1.00 54.43  ? 40  ILE   P CG1 1 
ATOM   5810 C CG2 . ILE   B 2 12  ? 171.114 147.122 163.049 1.00 53.11  ? 40  ILE   P CG2 1 
ATOM   5811 C CD1 . ILE   B 2 12  ? 173.298 145.266 161.715 1.00 58.83  ? 40  ILE   P CD1 1 
ATOM   5812 N N   . LEU   B 2 13  ? 172.790 150.585 162.256 1.00 64.85  ? 41  LEU   P N   1 
ATOM   5813 C CA  . LEU   B 2 13  ? 172.191 151.900 162.488 1.00 66.45  ? 41  LEU   P CA  1 
ATOM   5814 C C   . LEU   B 2 13  ? 172.470 152.831 161.304 1.00 75.44  ? 41  LEU   P C   1 
ATOM   5815 O O   . LEU   B 2 13  ? 173.083 153.891 161.429 1.00 77.09  ? 41  LEU   P O   1 
ATOM   5816 C CB  . LEU   B 2 13  ? 172.714 152.488 163.795 1.00 63.10  ? 41  LEU   P CB  1 
ATOM   5817 C CG  . LEU   B 2 13  ? 172.130 151.993 165.122 1.00 62.24  ? 41  LEU   P CG  1 
ATOM   5818 C CD1 . LEU   B 2 13  ? 172.186 150.477 165.261 1.00 64.73  ? 41  LEU   P CD1 1 
ATOM   5819 C CD2 . LEU   B 2 13  ? 172.871 152.659 166.266 1.00 65.26  ? 41  LEU   P CD2 1 
ATOM   5820 N N   . ASN   B 2 14  ? 172.011 152.398 160.132 1.00 84.79  ? 42  ASN   P N   1 
ATOM   5821 C CA  . ASN   B 2 14  ? 172.072 153.183 158.906 1.00 93.01  ? 42  ASN   P CA  1 
ATOM   5822 C C   . ASN   B 2 14  ? 170.650 153.400 158.415 1.00 108.14 ? 42  ASN   P C   1 
ATOM   5823 O O   . ASN   B 2 14  ? 169.910 152.433 158.213 1.00 112.78 ? 42  ASN   P O   1 
ATOM   5824 C CB  . ASN   B 2 14  ? 172.909 152.474 157.837 1.00 87.79  ? 42  ASN   P CB  1 
ATOM   5825 C CG  . ASN   B 2 14  ? 173.293 153.388 156.690 1.00 96.92  ? 42  ASN   P CG  1 
ATOM   5826 O OD1 . ASN   B 2 14  ? 173.402 154.603 156.855 1.00 101.85 ? 42  ASN   P OD1 1 
ATOM   5827 N ND2 . ASN   B 2 14  ? 173.503 152.806 155.516 1.00 95.52  ? 42  ASN   P ND2 1 
ATOM   5828 N N   . ARG   B 2 15  ? 170.278 154.665 158.221 1.00 121.42 ? 43  ARG   P N   1 
ATOM   5829 C CA  . ARG   B 2 15  ? 168.903 155.055 157.922 1.00 134.15 ? 43  ARG   P CA  1 
ATOM   5830 C C   . ARG   B 2 15  ? 168.396 154.375 156.649 1.00 141.41 ? 43  ARG   P C   1 
ATOM   5831 O O   . ARG   B 2 15  ? 168.846 154.722 155.550 1.00 143.14 ? 43  ARG   P O   1 
ATOM   5832 C CB  . ARG   B 2 15  ? 168.807 156.583 157.791 1.00 139.10 ? 43  ARG   P CB  1 
ATOM   5833 C CG  . ARG   B 2 15  ? 169.752 157.233 156.765 1.00 140.95 ? 43  ARG   P CG  1 
ATOM   5834 C CD  . ARG   B 2 15  ? 169.903 158.731 156.990 1.00 145.21 ? 43  ARG   P CD  1 
ATOM   5835 N NE  . ARG   B 2 15  ? 168.691 159.471 156.657 1.00 148.96 ? 43  ARG   P NE  1 
ATOM   5836 C CZ  . ARG   B 2 15  ? 168.604 160.795 156.601 1.00 149.73 ? 43  ARG   P CZ  1 
ATOM   5837 N NH1 . ARG   B 2 15  ? 169.644 161.574 156.858 1.00 147.54 ? 43  ARG   P NH1 1 
ATOM   5838 N NH2 . ARG   B 2 15  ? 167.442 161.354 156.275 1.00 151.16 ? 43  ARG   P NH2 1 
ATOM   5839 N N   . PRO   B 2 16  ? 167.474 153.382 156.733 1.00 147.85 ? 44  PRO   P N   1 
ATOM   5840 C CA  . PRO   B 2 16  ? 166.940 152.807 155.490 1.00 151.29 ? 44  PRO   P CA  1 
ATOM   5841 C C   . PRO   B 2 16  ? 166.019 153.767 154.752 1.00 158.89 ? 44  PRO   P C   1 
ATOM   5842 O O   . PRO   B 2 16  ? 166.208 154.040 153.562 1.00 164.63 ? 44  PRO   P O   1 
ATOM   5843 C CB  . PRO   B 2 16  ? 166.191 151.558 155.971 1.00 149.26 ? 44  PRO   P CB  1 
ATOM   5844 C CG  . PRO   B 2 16  ? 165.783 151.871 157.351 1.00 146.57 ? 44  PRO   P CG  1 
ATOM   5845 C CD  . PRO   B 2 16  ? 166.843 152.770 157.922 1.00 144.93 ? 44  PRO   P CD  1 
ATOM   5846 N N   . LYS   B 2 17  ? 165.026 154.299 155.469 1.00 158.99 ? 45  LYS   P N   1 
ATOM   5847 C CA  . LYS   B 2 17  ? 164.023 155.147 154.834 1.00 163.16 ? 45  LYS   P CA  1 
ATOM   5848 C C   . LYS   B 2 17  ? 164.617 156.478 154.397 1.00 171.08 ? 45  LYS   P C   1 
ATOM   5849 O O   . LYS   B 2 17  ? 164.339 156.953 153.290 1.00 176.49 ? 45  LYS   P O   1 
ATOM   5850 N N   . ARG   B 2 18  ? 165.434 157.096 155.254 1.00 167.23 ? 46  ARG   P N   1 
ATOM   5851 C CA  . ARG   B 2 18  ? 166.062 158.362 154.892 1.00 168.04 ? 46  ARG   P CA  1 
ATOM   5852 C C   . ARG   B 2 18  ? 166.992 158.193 153.698 1.00 173.49 ? 46  ARG   P C   1 
ATOM   5853 O O   . ARG   B 2 18  ? 166.985 159.017 152.775 1.00 181.22 ? 46  ARG   P O   1 
ATOM   5854 N N   . TYR   B 2 19  ? 167.799 157.130 153.698 1.00 168.72 ? 47  TYR   P N   1 
ATOM   5855 C CA  . TYR   B 2 19  ? 168.705 156.883 152.582 1.00 174.58 ? 47  TYR   P CA  1 
ATOM   5856 C C   . TYR   B 2 19  ? 167.933 156.641 151.291 1.00 184.36 ? 47  TYR   P C   1 
ATOM   5857 O O   . TYR   B 2 19  ? 168.287 157.174 150.233 1.00 191.09 ? 47  TYR   P O   1 
ATOM   5858 N N   . ASN   B 2 20  ? 166.871 155.832 151.359 1.00 181.47 ? 48  ASN   P N   1 
ATOM   5859 C CA  . ASN   B 2 20  ? 166.070 155.565 150.169 1.00 184.77 ? 48  ASN   P CA  1 
ATOM   5860 C C   . ASN   B 2 20  ? 165.412 156.836 149.644 1.00 191.27 ? 48  ASN   P C   1 
ATOM   5861 O O   . ASN   B 2 20  ? 165.398 157.079 148.431 1.00 197.40 ? 48  ASN   P O   1 
ATOM   5862 N N   . SER   B 2 21  ? 164.867 157.661 150.542 1.00 188.78 ? 49  SER   P N   1 
ATOM   5863 C CA  . SER   B 2 21  ? 164.228 158.903 150.121 1.00 192.60 ? 49  SER   P CA  1 
ATOM   5864 C C   . SER   B 2 21  ? 165.238 159.855 149.494 1.00 198.42 ? 49  SER   P C   1 
ATOM   5865 O O   . SER   B 2 21  ? 164.953 160.497 148.477 1.00 202.78 ? 49  SER   P O   1 
ATOM   5866 N N   . GLY   B 2 22  ? 166.425 159.968 150.095 1.00 196.80 ? 50  GLY   P N   1 
ATOM   5867 C CA  . GLY   B 2 22  ? 167.454 160.819 149.520 1.00 198.63 ? 50  GLY   P CA  1 
ATOM   5868 C C   . GLY   B 2 22  ? 167.903 160.341 148.152 1.00 202.79 ? 50  GLY   P C   1 
ATOM   5869 O O   . GLY   B 2 22  ? 168.079 161.143 147.231 1.00 206.66 ? 50  GLY   P O   1 
ATOM   5870 N N   . LYS   B 2 23  ? 168.092 159.028 148.001 1.00 202.16 ? 51  LYS   P N   1 
ATOM   5871 C CA  . LYS   B 2 23  ? 168.481 158.481 146.705 1.00 204.97 ? 51  LYS   P CA  1 
ATOM   5872 C C   . LYS   B 2 23  ? 167.404 158.727 145.656 1.00 209.19 ? 51  LYS   P C   1 
ATOM   5873 O O   . LYS   B 2 23  ? 167.711 159.082 144.512 1.00 212.49 ? 51  LYS   P O   1 
ATOM   5874 N N   . LEU   B 2 24  ? 166.134 158.538 146.026 1.00 208.42 ? 52  LEU   P N   1 
ATOM   5875 C CA  . LEU   B 2 24  ? 165.049 158.775 145.079 1.00 210.97 ? 52  LEU   P CA  1 
ATOM   5876 C C   . LEU   B 2 24  ? 164.969 160.244 144.681 1.00 215.19 ? 52  LEU   P C   1 
ATOM   5877 O O   . LEU   B 2 24  ? 164.849 160.565 143.493 1.00 217.58 ? 52  LEU   P O   1 
ATOM   5878 N N   . GLU   B 2 25  ? 165.033 161.151 145.660 1.00 214.15 ? 53  GLU   P N   1 
ATOM   5879 C CA  . GLU   B 2 25  ? 164.943 162.576 145.358 1.00 216.61 ? 53  GLU   P CA  1 
ATOM   5880 C C   . GLU   B 2 25  ? 166.113 163.039 144.500 1.00 216.58 ? 53  GLU   P C   1 
ATOM   5881 O O   . GLU   B 2 25  ? 165.927 163.803 143.545 1.00 218.03 ? 53  GLU   P O   1 
ATOM   5882 N N   . GLU   B 2 26  ? 167.328 162.592 144.826 1.00 215.43 ? 54  GLU   P N   1 
ATOM   5883 C CA  . GLU   B 2 26  ? 168.490 162.968 144.027 1.00 215.68 ? 54  GLU   P CA  1 
ATOM   5884 C C   . GLU   B 2 26  ? 168.405 162.394 142.618 1.00 217.67 ? 54  GLU   P C   1 
ATOM   5885 O O   . GLU   B 2 26  ? 168.802 163.051 141.649 1.00 218.69 ? 54  GLU   P O   1 
ATOM   5886 N N   . PHE   B 2 27  ? 167.895 161.171 142.487 1.00 217.57 ? 55  PHE   P N   1 
ATOM   5887 C CA  . PHE   B 2 27  ? 167.799 160.535 141.181 1.00 217.27 ? 55  PHE   P CA  1 
ATOM   5888 C C   . PHE   B 2 27  ? 166.820 161.289 140.289 1.00 217.99 ? 55  PHE   P C   1 
ATOM   5889 O O   . PHE   B 2 27  ? 165.791 161.792 140.749 1.00 218.86 ? 55  PHE   P O   1 
ATOM   5890 N N   . VAL   B 2 28  ? 167.152 161.367 138.998 1.00 217.42 ? 56  VAL   P N   1 
ATOM   5891 C CA  . VAL   B 2 28  ? 166.274 162.031 138.038 1.00 217.29 ? 56  VAL   P CA  1 
ATOM   5892 C C   . VAL   B 2 28  ? 164.957 161.283 137.892 1.00 217.26 ? 56  VAL   P C   1 
ATOM   5893 O O   . VAL   B 2 28  ? 163.902 161.900 137.698 1.00 217.52 ? 56  VAL   P O   1 
ATOM   5894 N N   . GLN   B 2 29  ? 164.991 159.949 137.973 1.00 216.63 ? 57  GLN   P N   1 
ATOM   5895 C CA  . GLN   B 2 29  ? 163.767 159.164 137.845 1.00 215.75 ? 57  GLN   P CA  1 
ATOM   5896 C C   . GLN   B 2 29  ? 162.778 159.465 138.964 1.00 217.42 ? 57  GLN   P C   1 
ATOM   5897 O O   . GLN   B 2 29  ? 161.566 159.314 138.774 1.00 217.23 ? 57  GLN   P O   1 
ATOM   5898 N N   . GLY   B 2 30  ? 163.271 159.891 140.126 1.00 219.09 ? 58  GLY   P N   1 
ATOM   5899 C CA  . GLY   B 2 30  ? 162.416 160.244 141.242 1.00 220.45 ? 58  GLY   P CA  1 
ATOM   5900 C C   . GLY   B 2 30  ? 162.102 161.725 141.276 1.00 221.71 ? 58  GLY   P C   1 
ATOM   5901 O O   . GLY   B 2 30  ? 161.426 162.242 140.382 1.00 221.74 ? 58  GLY   P O   1 
ATOM   5902 N N   . ASN   B 2 31  ? 162.587 162.420 142.304 1.00 222.73 ? 59  ASN   P N   1 
ATOM   5903 C CA  . ASN   B 2 31  ? 162.310 163.843 142.461 1.00 223.87 ? 59  ASN   P CA  1 
ATOM   5904 C C   . ASN   B 2 31  ? 160.844 164.054 142.813 1.00 226.86 ? 59  ASN   P C   1 
ATOM   5905 O O   . ASN   B 2 31  ? 160.511 164.325 143.972 1.00 228.73 ? 59  ASN   P O   1 
ATOM   5906 N N   . LEU   B 2 32  ? 159.960 163.936 141.819 1.00 226.41 ? 60  LEU   P N   1 
ATOM   5907 C CA  . LEU   B 2 32  ? 158.530 163.963 142.106 1.00 227.84 ? 60  LEU   P CA  1 
ATOM   5908 C C   . LEU   B 2 32  ? 158.131 162.784 142.983 1.00 228.86 ? 60  LEU   P C   1 
ATOM   5909 O O   . LEU   B 2 32  ? 157.368 162.942 143.943 1.00 230.25 ? 60  LEU   P O   1 
ATOM   5910 N N   . GLU   B 2 33  ? 158.651 161.593 142.676 1.00 227.79 ? 61  GLU   P N   1 
ATOM   5911 C CA  . GLU   B 2 33  ? 158.404 160.438 143.530 1.00 227.61 ? 61  GLU   P CA  1 
ATOM   5912 C C   . GLU   B 2 33  ? 159.057 160.615 144.895 1.00 229.42 ? 61  GLU   P C   1 
ATOM   5913 O O   . GLU   B 2 33  ? 158.467 160.260 145.921 1.00 229.52 ? 61  GLU   P O   1 
ATOM   5914 N N   . ARG   B 2 34  ? 160.277 161.155 144.924 1.00 229.46 ? 62  ARG   P N   1 
ATOM   5915 C CA  . ARG   B 2 34  ? 160.935 161.437 146.197 1.00 229.02 ? 62  ARG   P CA  1 
ATOM   5916 C C   . ARG   B 2 34  ? 160.142 162.454 147.010 1.00 230.55 ? 62  ARG   P C   1 
ATOM   5917 O O   . ARG   B 2 34  ? 159.988 162.309 148.228 1.00 230.39 ? 62  ARG   P O   1 
ATOM   5918 N N   . GLU   B 2 35  ? 159.641 163.501 146.350 1.00 230.38 ? 63  GLU   P N   1 
ATOM   5919 C CA  . GLU   B 2 35  ? 158.837 164.499 147.049 1.00 229.61 ? 63  GLU   P CA  1 
ATOM   5920 C C   . GLU   B 2 35  ? 157.552 163.891 147.595 1.00 230.74 ? 63  GLU   P C   1 
ATOM   5921 O O   . GLU   B 2 35  ? 157.143 164.194 148.722 1.00 231.49 ? 63  GLU   P O   1 
ATOM   5922 N N   . CYS   B 2 36  ? 156.898 163.032 146.808 1.00 230.82 ? 64  CYS   P N   1 
ATOM   5923 C CA  . CYS   B 2 36  ? 155.689 162.367 147.284 1.00 229.35 ? 64  CYS   P CA  1 
ATOM   5924 C C   . CYS   B 2 36  ? 155.989 161.463 148.473 1.00 229.45 ? 64  CYS   P C   1 
ATOM   5925 O O   . CYS   B 2 36  ? 155.213 161.410 149.435 1.00 229.07 ? 64  CYS   P O   1 
ATOM   5926 N N   . MET   B 2 37  ? 157.107 160.735 148.420 1.00 229.18 ? 65  MET   P N   1 
ATOM   5927 C CA  . MET   B 2 37  ? 157.491 159.878 149.536 1.00 227.26 ? 65  MET   P CA  1 
ATOM   5928 C C   . MET   B 2 37  ? 157.767 160.695 150.792 1.00 227.91 ? 65  MET   P C   1 
ATOM   5929 O O   . MET   B 2 37  ? 157.373 160.302 151.895 1.00 226.51 ? 65  MET   P O   1 
ATOM   5930 N N   . GLU   B 2 38  ? 158.459 161.827 150.646 1.00 229.35 ? 66  GLU   P N   1 
ATOM   5931 C CA  . GLU   B 2 38  ? 158.724 162.685 151.797 1.00 229.07 ? 66  GLU   P CA  1 
ATOM   5932 C C   . GLU   B 2 38  ? 157.428 163.235 152.381 1.00 228.45 ? 66  GLU   P C   1 
ATOM   5933 O O   . GLU   B 2 38  ? 157.229 163.226 153.602 1.00 226.24 ? 66  GLU   P O   1 
ATOM   5934 N N   . GLU   B 2 39  ? 156.530 163.719 151.520 1.00 229.98 ? 67  GLU   P N   1 
ATOM   5935 C CA  . GLU   B 2 39  ? 155.231 164.186 151.994 1.00 229.48 ? 67  GLU   P CA  1 
ATOM   5936 C C   . GLU   B 2 39  ? 154.385 163.030 152.514 1.00 228.76 ? 67  GLU   P C   1 
ATOM   5937 O O   . GLU   B 2 39  ? 153.660 163.179 153.504 1.00 228.86 ? 67  GLU   P O   1 
ATOM   5938 N N   . LYS   B 2 40  ? 154.465 161.876 151.859 1.00 227.74 ? 68  LYS   P N   1 
ATOM   5939 C CA  . LYS   B 2 40  ? 153.709 160.697 152.249 1.00 224.47 ? 68  LYS   P CA  1 
ATOM   5940 C C   . LYS   B 2 40  ? 154.511 159.879 153.260 1.00 221.95 ? 68  LYS   P C   1 
ATOM   5941 O O   . LYS   B 2 40  ? 155.516 160.338 153.809 1.00 224.05 ? 68  LYS   P O   1 
ATOM   5942 N N   . CYS   B 2 41  ? 154.061 158.657 153.531 1.00 218.03 ? 69  CYS   P N   1 
ATOM   5943 C CA  . CYS   B 2 41  ? 154.767 157.782 154.452 1.00 215.25 ? 69  CYS   P CA  1 
ATOM   5944 C C   . CYS   B 2 41  ? 156.080 157.309 153.827 1.00 213.99 ? 69  CYS   P C   1 
ATOM   5945 O O   . CYS   B 2 41  ? 156.388 157.586 152.664 1.00 214.75 ? 69  CYS   P O   1 
ATOM   5946 N N   . SER   B 2 42  ? 156.866 156.587 154.622 1.00 211.33 ? 70  SER   P N   1 
ATOM   5947 C CA  . SER   B 2 42  ? 158.162 156.107 154.162 1.00 208.62 ? 70  SER   P CA  1 
ATOM   5948 C C   . SER   B 2 42  ? 157.989 155.101 153.030 1.00 206.42 ? 70  SER   P C   1 
ATOM   5949 O O   . SER   B 2 42  ? 157.009 154.353 152.983 1.00 206.99 ? 70  SER   P O   1 
ATOM   5950 N N   . PHE   B 2 43  ? 158.956 155.093 152.107 1.00 204.14 ? 71  PHE   P N   1 
ATOM   5951 C CA  . PHE   B 2 43  ? 158.922 154.139 151.002 1.00 203.83 ? 71  PHE   P CA  1 
ATOM   5952 C C   . PHE   B 2 43  ? 158.976 152.698 151.495 1.00 205.98 ? 71  PHE   P C   1 
ATOM   5953 O O   . PHE   B 2 43  ? 158.490 151.790 150.810 1.00 206.00 ? 71  PHE   P O   1 
ATOM   5954 N N   . GLU   B 2 44  ? 159.571 152.467 152.668 1.00 206.48 ? 72  GLU   P N   1 
ATOM   5955 C CA  . GLU   B 2 44  ? 159.583 151.125 153.240 1.00 206.38 ? 72  GLU   P CA  1 
ATOM   5956 C C   . GLU   B 2 44  ? 158.168 150.629 153.505 1.00 205.08 ? 72  GLU   P C   1 
ATOM   5957 O O   . GLU   B 2 44  ? 157.863 149.453 153.281 1.00 203.27 ? 72  GLU   P O   1 
ATOM   5958 N N   . GLU   B 2 45  ? 157.287 151.513 153.981 1.00 205.71 ? 73  GLU   P N   1 
ATOM   5959 C CA  . GLU   B 2 45  ? 155.890 151.134 154.171 1.00 204.27 ? 73  GLU   P CA  1 
ATOM   5960 C C   . GLU   B 2 45  ? 155.228 150.777 152.845 1.00 204.81 ? 73  GLU   P C   1 
ATOM   5961 O O   . GLU   B 2 45  ? 154.452 149.817 152.766 1.00 203.14 ? 73  GLU   P O   1 
ATOM   5962 N N   . ALA   B 2 46  ? 155.521 151.544 151.791 1.00 206.68 ? 74  ALA   P N   1 
ATOM   5963 C CA  . ALA   B 2 46  ? 154.954 151.247 150.480 1.00 204.68 ? 74  ALA   P CA  1 
ATOM   5964 C C   . ALA   B 2 46  ? 155.418 149.886 149.979 1.00 201.83 ? 74  ALA   P C   1 
ATOM   5965 O O   . ALA   B 2 46  ? 154.623 149.112 149.433 1.00 197.79 ? 74  ALA   P O   1 
ATOM   5966 C CB  . ALA   B 2 46  ? 155.333 152.342 149.484 1.00 202.69 ? 74  ALA   P CB  1 
ATOM   5967 N N   . ARG   B 2 47  ? 156.706 149.577 150.152 1.00 202.60 ? 75  ARG   P N   1 
ATOM   5968 C CA  . ARG   B 2 47  ? 157.203 148.257 149.777 1.00 198.91 ? 75  ARG   P CA  1 
ATOM   5969 C C   . ARG   B 2 47  ? 156.550 147.163 150.613 1.00 195.85 ? 75  ARG   P C   1 
ATOM   5970 O O   . ARG   B 2 47  ? 156.216 146.091 150.097 1.00 192.41 ? 75  ARG   P O   1 
ATOM   5971 N N   . GLU   B 2 48  ? 156.362 147.417 151.911 1.00 197.52 ? 76  GLU   P N   1 
ATOM   5972 C CA  . GLU   B 2 48  ? 155.711 146.440 152.777 1.00 194.08 ? 76  GLU   P CA  1 
ATOM   5973 C C   . GLU   B 2 48  ? 154.253 146.223 152.393 1.00 191.63 ? 76  GLU   P C   1 
ATOM   5974 O O   . GLU   B 2 48  ? 153.683 145.169 152.701 1.00 189.31 ? 76  GLU   P O   1 
ATOM   5975 N N   . VAL   B 2 49  ? 153.628 147.211 151.746 1.00 190.90 ? 77  VAL   P N   1 
ATOM   5976 C CA  . VAL   B 2 49  ? 152.243 147.055 151.302 1.00 182.65 ? 77  VAL   P CA  1 
ATOM   5977 C C   . VAL   B 2 49  ? 152.120 145.878 150.340 1.00 176.19 ? 77  VAL   P C   1 
ATOM   5978 O O   . VAL   B 2 49  ? 151.201 145.057 150.449 1.00 174.83 ? 77  VAL   P O   1 
ATOM   5979 N N   . PHE   B 2 50  ? 153.041 145.781 149.385 1.00 172.33 ? 78  PHE   P N   1 
ATOM   5980 C CA  . PHE   B 2 50  ? 153.165 144.688 148.426 1.00 162.21 ? 78  PHE   P CA  1 
ATOM   5981 C C   . PHE   B 2 50  ? 152.119 144.698 147.317 1.00 158.48 ? 78  PHE   P C   1 
ATOM   5982 O O   . PHE   B 2 50  ? 152.189 143.847 146.424 1.00 157.78 ? 78  PHE   P O   1 
ATOM   5983 N N   . GLU   B 2 51  ? 151.155 145.616 147.337 1.00 159.80 ? 79  GLU   P N   1 
ATOM   5984 C CA  . GLU   B 2 51  ? 150.145 145.711 146.294 1.00 154.83 ? 79  GLU   P CA  1 
ATOM   5985 C C   . GLU   B 2 51  ? 150.387 146.856 145.319 1.00 161.16 ? 79  GLU   P C   1 
ATOM   5986 O O   . GLU   B 2 51  ? 149.577 147.054 144.408 1.00 163.99 ? 79  GLU   P O   1 
ATOM   5987 N N   . ASN   B 2 52  ? 151.468 147.618 145.489 1.00 162.90 ? 80  ASN   P N   1 
ATOM   5988 C CA  . ASN   B 2 52  ? 151.744 148.734 144.596 1.00 167.83 ? 80  ASN   P CA  1 
ATOM   5989 C C   . ASN   B 2 52  ? 151.992 148.232 143.179 1.00 175.42 ? 80  ASN   P C   1 
ATOM   5990 O O   . ASN   B 2 52  ? 152.603 147.181 142.971 1.00 174.40 ? 80  ASN   P O   1 
ATOM   5991 N N   . THR   B 2 53  ? 151.507 148.995 142.198 1.00 179.72 ? 81  THR   P N   1 
ATOM   5992 C CA  . THR   B 2 53  ? 151.652 148.638 140.787 1.00 182.85 ? 81  THR   P CA  1 
ATOM   5993 C C   . THR   B 2 53  ? 153.021 149.103 140.299 1.00 188.79 ? 81  THR   P C   1 
ATOM   5994 O O   . THR   B 2 53  ? 153.178 150.160 139.682 1.00 189.68 ? 81  THR   P O   1 
ATOM   5995 N N   . GLU   B 2 54  ? 154.032 148.278 140.576 1.00 191.54 ? 82  GLU   P N   1 
ATOM   5996 C CA  . GLU   B 2 54  ? 155.408 148.532 140.150 1.00 198.44 ? 82  GLU   P CA  1 
ATOM   5997 C C   . GLU   B 2 54  ? 155.926 149.873 140.675 1.00 204.18 ? 82  GLU   P C   1 
ATOM   5998 O O   . GLU   B 2 54  ? 156.361 150.745 139.920 1.00 209.58 ? 82  GLU   P O   1 
ATOM   5999 N N   . ARG   B 2 55  ? 155.860 150.026 142.001 1.00 202.45 ? 83  ARG   P N   1 
ATOM   6000 C CA  . ARG   B 2 55  ? 156.341 151.253 142.628 1.00 207.52 ? 83  ARG   P CA  1 
ATOM   6001 C C   . ARG   B 2 55  ? 157.830 151.458 142.376 1.00 214.06 ? 83  ARG   P C   1 
ATOM   6002 O O   . ARG   B 2 55  ? 158.269 152.574 142.074 1.00 217.39 ? 83  ARG   P O   1 
ATOM   6003 N N   . THR   B 2 56  ? 158.624 150.391 142.498 1.00 214.14 ? 84  THR   P N   1 
ATOM   6004 C CA  . THR   B 2 56  ? 160.052 150.495 142.216 1.00 214.83 ? 84  THR   P CA  1 
ATOM   6005 C C   . THR   B 2 56  ? 160.302 150.855 140.757 1.00 216.94 ? 84  THR   P C   1 
ATOM   6006 O O   . THR   B 2 56  ? 161.145 151.709 140.455 1.00 218.19 ? 84  THR   P O   1 
ATOM   6007 N N   . THR   B 2 57  ? 159.583 150.207 139.837 1.00 216.72 ? 85  THR   P N   1 
ATOM   6008 C CA  . THR   B 2 57  ? 159.739 150.519 138.419 1.00 217.48 ? 85  THR   P CA  1 
ATOM   6009 C C   . THR   B 2 57  ? 159.332 151.956 138.120 1.00 218.03 ? 85  THR   P C   1 
ATOM   6010 O O   . THR   B 2 57  ? 160.005 152.652 137.351 1.00 218.85 ? 85  THR   P O   1 
ATOM   6011 N N   . GLU   B 2 58  ? 158.225 152.414 138.711 1.00 217.15 ? 86  GLU   P N   1 
ATOM   6012 C CA  . GLU   B 2 58  ? 157.790 153.791 138.501 1.00 217.97 ? 86  GLU   P CA  1 
ATOM   6013 C C   . GLU   B 2 58  ? 158.816 154.784 139.033 1.00 218.86 ? 86  GLU   P C   1 
ATOM   6014 O O   . GLU   B 2 58  ? 159.107 155.796 138.385 1.00 218.23 ? 86  GLU   P O   1 
ATOM   6015 N N   . PHE   B 2 59  ? 159.370 154.515 140.218 1.00 219.60 ? 87  PHE   P N   1 
ATOM   6016 C CA  . PHE   B 2 59  ? 160.395 155.394 140.771 1.00 218.55 ? 87  PHE   P CA  1 
ATOM   6017 C C   . PHE   B 2 59  ? 161.642 155.410 139.895 1.00 218.11 ? 87  PHE   P C   1 
ATOM   6018 O O   . PHE   B 2 59  ? 162.261 156.462 139.702 1.00 217.31 ? 87  PHE   P O   1 
ATOM   6019 N N   . TRP   B 2 60  ? 162.030 154.248 139.362 1.00 218.28 ? 88  TRP   P N   1 
ATOM   6020 C CA  . TRP   B 2 60  ? 163.197 154.187 138.488 1.00 216.81 ? 88  TRP   P CA  1 
ATOM   6021 C C   . TRP   B 2 60  ? 162.984 155.004 137.220 1.00 215.60 ? 88  TRP   P C   1 
ATOM   6022 O O   . TRP   B 2 60  ? 163.887 155.723 136.776 1.00 213.31 ? 88  TRP   P O   1 
ATOM   6023 N N   . LYS   B 2 61  ? 161.801 154.906 136.623 1.00 215.59 ? 89  LYS   P N   1 
ATOM   6024 C CA  . LYS   B 2 61  ? 161.494 155.645 135.404 1.00 212.71 ? 89  LYS   P CA  1 
ATOM   6025 C C   . LYS   B 2 61  ? 161.173 157.103 135.714 1.00 211.87 ? 89  LYS   P C   1 
ATOM   6026 O O   . LYS   B 2 61  ? 161.955 158.001 135.403 1.00 211.75 ? 89  LYS   P O   1 
HETATM 6027 C C1  . NAG   C 3 .   ? 182.350 138.916 176.686 1.00 72.47  ? 1   NAG   B C1  1 
HETATM 6028 C C2  . NAG   C 3 .   ? 183.509 137.953 176.418 1.00 76.56  ? 1   NAG   B C2  1 
HETATM 6029 C C3  . NAG   C 3 .   ? 183.074 136.889 175.420 1.00 86.20  ? 1   NAG   B C3  1 
HETATM 6030 C C4  . NAG   C 3 .   ? 181.842 136.176 175.952 1.00 89.84  ? 1   NAG   B C4  1 
HETATM 6031 C C5  . NAG   C 3 .   ? 180.752 137.214 176.230 1.00 88.92  ? 1   NAG   B C5  1 
HETATM 6032 C C6  . NAG   C 3 .   ? 179.496 136.602 176.810 1.00 89.47  ? 1   NAG   B C6  1 
HETATM 6033 C C7  . NAG   C 3 .   ? 185.937 138.303 176.234 1.00 86.15  ? 1   NAG   B C7  1 
HETATM 6034 C C8  . NAG   C 3 .   ? 187.005 139.168 175.613 1.00 85.50  ? 1   NAG   B C8  1 
HETATM 6035 N N2  . NAG   C 3 .   ? 184.670 138.645 175.934 1.00 78.17  ? 1   NAG   B N2  1 
HETATM 6036 O O3  . NAG   C 3 .   ? 184.151 136.014 175.231 1.00 92.45  ? 1   NAG   B O3  1 
HETATM 6037 O O4  . NAG   C 3 .   ? 181.443 135.232 174.984 1.00 88.93  ? 1   NAG   B O4  1 
HETATM 6038 O O5  . NAG   C 3 .   ? 181.230 138.193 177.135 1.00 85.29  ? 1   NAG   B O5  1 
HETATM 6039 O O6  . NAG   C 3 .   ? 179.214 135.388 176.157 1.00 87.38  ? 1   NAG   B O6  1 
HETATM 6040 O O7  . NAG   C 3 .   ? 186.226 137.361 176.956 1.00 91.94  ? 1   NAG   B O7  1 
HETATM 6041 C C1  . NAG   C 3 .   ? 181.117 134.000 174.309 1.00 100.86 ? 2   NAG   B C1  1 
HETATM 6042 C C2  . NAG   C 3 .   ? 180.548 133.086 173.215 1.00 106.11 ? 2   NAG   B C2  1 
HETATM 6043 C C3  . NAG   C 3 .   ? 181.287 131.753 173.220 1.00 109.89 ? 2   NAG   B C3  1 
HETATM 6044 C C4  . NAG   C 3 .   ? 182.784 132.000 173.106 1.00 112.35 ? 2   NAG   B C4  1 
HETATM 6045 C C5  . NAG   C 3 .   ? 183.225 132.934 174.236 1.00 109.38 ? 2   NAG   B C5  1 
HETATM 6046 C C6  . NAG   C 3 .   ? 184.707 133.235 174.219 1.00 109.22 ? 2   NAG   B C6  1 
HETATM 6047 C C7  . NAG   C 3 .   ? 178.233 132.844 172.385 1.00 96.33  ? 2   NAG   B C7  1 
HETATM 6048 C C8  . NAG   C 3 .   ? 176.809 132.597 172.819 1.00 90.46  ? 2   NAG   B C8  1 
HETATM 6049 N N2  . NAG   C 3 .   ? 179.136 132.869 173.385 1.00 101.45 ? 2   NAG   B N2  1 
HETATM 6050 O O3  . NAG   C 3 .   ? 180.796 130.977 172.160 1.00 106.61 ? 2   NAG   B O3  1 
HETATM 6051 O O4  . NAG   C 3 .   ? 183.424 130.747 173.184 1.00 116.33 ? 2   NAG   B O4  1 
HETATM 6052 O O5  . NAG   C 3 .   ? 182.507 134.150 174.147 1.00 102.47 ? 2   NAG   B O5  1 
HETATM 6053 O O6  . NAG   C 3 .   ? 185.010 134.049 173.110 1.00 108.14 ? 2   NAG   B O6  1 
HETATM 6054 O O7  . NAG   C 3 .   ? 178.517 133.006 171.209 1.00 91.61  ? 2   NAG   B O7  1 
HETATM 6055 C C1  . NAG   D 3 .   ? 172.687 161.869 173.673 1.00 77.17  ? 1   NAG   C C1  1 
HETATM 6056 C C2  . NAG   D 3 .   ? 172.485 163.375 173.745 1.00 75.00  ? 1   NAG   C C2  1 
HETATM 6057 C C3  . NAG   D 3 .   ? 171.016 163.735 173.534 1.00 79.57  ? 1   NAG   C C3  1 
HETATM 6058 C C4  . NAG   D 3 .   ? 170.104 162.922 174.444 1.00 84.83  ? 1   NAG   C C4  1 
HETATM 6059 C C5  . NAG   D 3 .   ? 170.451 161.435 174.422 1.00 80.54  ? 1   NAG   C C5  1 
HETATM 6060 C C6  . NAG   D 3 .   ? 170.095 160.763 173.115 1.00 78.98  ? 1   NAG   C C6  1 
HETATM 6061 C C7  . NAG   D 3 .   ? 174.209 164.356 175.188 1.00 77.87  ? 1   NAG   C C7  1 
HETATM 6062 C C8  . NAG   D 3 .   ? 174.535 164.866 176.559 1.00 78.87  ? 1   NAG   C C8  1 
HETATM 6063 N N2  . NAG   D 3 .   ? 172.964 163.903 175.011 1.00 72.59  ? 1   NAG   C N2  1 
HETATM 6064 O O3  . NAG   D 3 .   ? 170.663 163.518 172.171 1.00 77.30  ? 1   NAG   C O3  1 
HETATM 6065 O O4  . NAG   D 3 .   ? 170.195 163.407 175.779 1.00 88.35  ? 1   NAG   C O4  1 
HETATM 6066 O O5  . NAG   D 3 .   ? 171.857 161.230 174.622 1.00 79.50  ? 1   NAG   C O5  1 
HETATM 6067 O O6  . NAG   D 3 .   ? 170.832 159.561 172.931 1.00 76.92  ? 1   NAG   C O6  1 
HETATM 6068 O O7  . NAG   D 3 .   ? 175.035 164.356 174.281 1.00 78.67  ? 1   NAG   C O7  1 
HETATM 6069 C C1  . NAG   D 3 .   ? 168.990 164.100 176.161 1.00 100.06 ? 2   NAG   C C1  1 
HETATM 6070 C C2  . NAG   D 3 .   ? 167.861 163.449 176.957 1.00 97.74  ? 2   NAG   C C2  1 
HETATM 6071 C C3  . NAG   D 3 .   ? 166.844 164.501 177.382 1.00 99.01  ? 2   NAG   C C3  1 
HETATM 6072 C C4  . NAG   D 3 .   ? 167.535 165.636 178.128 1.00 100.48 ? 2   NAG   C C4  1 
HETATM 6073 C C5  . NAG   D 3 .   ? 168.678 166.194 177.287 1.00 99.87  ? 2   NAG   C C5  1 
HETATM 6074 C C6  . NAG   D 3 .   ? 169.486 167.245 178.012 1.00 99.62  ? 2   NAG   C C6  1 
HETATM 6075 C C7  . NAG   D 3 .   ? 167.053 161.152 176.648 1.00 101.94 ? 2   NAG   C C7  1 
HETATM 6076 C C8  . NAG   D 3 .   ? 167.578 160.888 178.027 1.00 98.79  ? 2   NAG   C C8  1 
HETATM 6077 N N2  . NAG   D 3 .   ? 167.218 162.397 176.188 1.00 99.73  ? 2   NAG   C N2  1 
HETATM 6078 O O3  . NAG   D 3 .   ? 165.859 163.899 178.216 1.00 100.67 ? 2   NAG   C O3  1 
HETATM 6079 O O4  . NAG   D 3 .   ? 166.604 166.674 178.406 1.00 102.23 ? 2   NAG   C O4  1 
HETATM 6080 O O5  . NAG   D 3 .   ? 169.588 165.141 176.937 1.00 100.95 ? 2   NAG   C O5  1 
HETATM 6081 O O6  . NAG   D 3 .   ? 168.649 168.130 178.744 1.00 101.34 ? 2   NAG   C O6  1 
HETATM 6082 O O7  . NAG   D 3 .   ? 166.508 160.280 175.981 1.00 102.94 ? 2   NAG   C O7  1 
HETATM 6083 C C1  . NAG   E 3 .   ? 174.750 161.054 159.595 1.00 88.00  ? 1   NAG   D C1  1 
HETATM 6084 C C2  . NAG   E 3 .   ? 174.301 160.142 158.451 1.00 88.86  ? 1   NAG   D C2  1 
HETATM 6085 C C3  . NAG   E 3 .   ? 174.968 160.595 157.159 1.00 93.53  ? 1   NAG   D C3  1 
HETATM 6086 C C4  . NAG   E 3 .   ? 174.675 162.068 156.911 1.00 89.37  ? 1   NAG   D C4  1 
HETATM 6087 C C5  . NAG   E 3 .   ? 175.075 162.883 158.143 1.00 90.20  ? 1   NAG   D C5  1 
HETATM 6088 C C6  . NAG   E 3 .   ? 174.756 164.354 158.014 1.00 93.68  ? 1   NAG   D C6  1 
HETATM 6089 C C7  . NAG   E 3 .   ? 175.807 158.268 159.033 1.00 82.92  ? 1   NAG   D C7  1 
HETATM 6090 C C8  . NAG   E 3 .   ? 175.840 156.778 159.261 1.00 81.06  ? 1   NAG   D C8  1 
HETATM 6091 N N2  . NAG   E 3 .   ? 174.596 158.759 158.717 1.00 86.31  ? 1   NAG   D N2  1 
HETATM 6092 O O3  . NAG   E 3 .   ? 174.490 159.786 156.119 1.00 99.58  ? 1   NAG   D O3  1 
HETATM 6093 O O4  . NAG   E 3 .   ? 175.412 162.453 155.774 1.00 93.08  ? 1   NAG   D O4  1 
HETATM 6094 O O5  . NAG   E 3 .   ? 174.411 162.381 159.285 1.00 87.86  ? 1   NAG   D O5  1 
HETATM 6095 O O6  . NAG   E 3 .   ? 175.443 164.889 156.908 1.00 95.44  ? 1   NAG   D O6  1 
HETATM 6096 O O7  . NAG   E 3 .   ? 176.815 158.950 159.128 1.00 80.74  ? 1   NAG   D O7  1 
HETATM 6097 C C1  . NAG   E 3 .   ? 175.966 162.944 154.539 1.00 104.36 ? 2   NAG   D C1  1 
HETATM 6098 C C2  . NAG   E 3 .   ? 177.143 163.579 153.792 1.00 107.08 ? 2   NAG   D C2  1 
HETATM 6099 C C3  . NAG   E 3 .   ? 177.075 163.192 152.319 1.00 109.79 ? 2   NAG   D C3  1 
HETATM 6100 C C4  . NAG   E 3 .   ? 176.997 161.678 152.189 1.00 109.98 ? 2   NAG   D C4  1 
HETATM 6101 C C5  . NAG   E 3 .   ? 175.794 161.171 152.986 1.00 108.02 ? 2   NAG   D C5  1 
HETATM 6102 C C6  . NAG   E 3 .   ? 175.613 159.670 152.918 1.00 108.38 ? 2   NAG   D C6  1 
HETATM 6103 C C7  . NAG   E 3 .   ? 178.138 165.889 154.089 1.00 112.17 ? 2   NAG   D C7  1 
HETATM 6104 C C8  . NAG   E 3 .   ? 179.559 165.369 154.115 1.00 107.88 ? 2   NAG   D C8  1 
HETATM 6105 N N2  . NAG   E 3 .   ? 177.111 165.016 153.939 1.00 108.43 ? 2   NAG   D N2  1 
HETATM 6106 O O3  . NAG   E 3 .   ? 178.199 163.716 151.666 1.00 113.14 ? 2   NAG   D O3  1 
HETATM 6107 O O4  . NAG   E 3 .   ? 176.872 161.386 150.817 1.00 110.45 ? 2   NAG   D O4  1 
HETATM 6108 O O5  . NAG   E 3 .   ? 175.946 161.551 154.340 1.00 106.35 ? 2   NAG   D O5  1 
HETATM 6109 O O6  . NAG   E 3 .   ? 174.255 159.342 153.096 1.00 105.88 ? 2   NAG   D O6  1 
HETATM 6110 O O7  . NAG   E 3 .   ? 177.939 167.089 154.201 1.00 112.76 ? 2   NAG   D O7  1 
HETATM 6111 C C11 . A1AVC F 4 .   ? 141.430 146.721 149.697 1.00 108.59 ? 801 A1AVC A C11 1 
HETATM 6112 C C12 . A1AVC F 4 .   ? 142.237 146.945 151.013 1.00 104.64 ? 801 A1AVC A C12 1 
HETATM 6113 C C13 . A1AVC F 4 .   ? 141.352 147.737 152.025 1.00 103.68 ? 801 A1AVC A C13 1 
HETATM 6114 C C14 . A1AVC F 4 .   ? 141.694 148.931 152.603 1.00 104.94 ? 801 A1AVC A C14 1 
HETATM 6115 C C15 . A1AVC F 4 .   ? 143.021 149.663 152.323 1.00 101.59 ? 801 A1AVC A C15 1 
HETATM 6116 C C16 . A1AVC F 4 .   ? 140.681 149.577 153.602 1.00 101.19 ? 801 A1AVC A C16 1 
HETATM 6117 C C01 . A1AVC F 4 .   ? 142.914 148.356 148.323 1.00 106.42 ? 801 A1AVC A C01 1 
HETATM 6118 C C02 . A1AVC F 4 .   ? 141.725 147.351 148.473 1.00 112.39 ? 801 A1AVC A C02 1 
HETATM 6119 C C03 . A1AVC F 4 .   ? 140.925 147.068 147.338 1.00 110.67 ? 801 A1AVC A C03 1 
HETATM 6120 C C04 . A1AVC F 4 .   ? 139.818 146.147 147.432 1.00 107.98 ? 801 A1AVC A C04 1 
HETATM 6121 C C05 . A1AVC F 4 .   ? 139.017 145.874 146.273 1.00 100.06 ? 801 A1AVC A C05 1 
HETATM 6122 C C06 . A1AVC F 4 .   ? 137.940 144.977 146.361 1.00 99.78  ? 801 A1AVC A C06 1 
HETATM 6123 C C07 . A1AVC F 4 .   ? 137.646 144.350 147.578 1.00 104.63 ? 801 A1AVC A C07 1 
HETATM 6124 C C08 . A1AVC F 4 .   ? 138.428 144.617 148.708 1.00 107.77 ? 801 A1AVC A C08 1 
HETATM 6125 C C09 . A1AVC F 4 .   ? 139.534 145.538 148.616 1.00 109.46 ? 801 A1AVC A C09 1 
HETATM 6126 C C10 . A1AVC F 4 .   ? 140.335 145.813 149.769 1.00 106.25 ? 801 A1AVC A C10 1 
HETATM 6127 C C17 . A1AVC F 4 .   ? 139.553 150.349 152.810 1.00 99.60  ? 801 A1AVC A C17 1 
HETATM 6128 C C18 . A1AVC F 4 .   ? 139.661 151.906 152.981 1.00 103.30 ? 801 A1AVC A C18 1 
HETATM 6129 C C19 . A1AVC F 4 .   ? 138.441 152.662 152.453 1.00 107.75 ? 801 A1AVC A C19 1 
HETATM 6130 C C20 . A1AVC F 4 .   ? 138.782 154.150 152.287 1.00 105.54 ? 801 A1AVC A C20 1 
HETATM 6131 C C21 . A1AVC F 4 .   ? 137.240 152.474 153.421 1.00 104.73 ? 801 A1AVC A C21 1 
HETATM 6132 C C22 . A1AVC F 4 .   ? 136.124 153.564 153.295 1.00 108.59 ? 801 A1AVC A C22 1 
HETATM 6133 C C23 . A1AVC F 4 .   ? 134.793 153.166 153.964 1.00 110.85 ? 801 A1AVC A C23 1 
HETATM 6134 C C24 . A1AVC F 4 .   ? 133.582 153.981 153.422 1.00 117.58 ? 801 A1AVC A C24 1 
HETATM 6135 C C25 . A1AVC F 4 .   ? 133.927 155.464 153.354 1.00 113.57 ? 801 A1AVC A C25 1 
HETATM 6136 C C26 . A1AVC F 4 .   ? 132.326 153.759 154.276 1.00 118.31 ? 801 A1AVC A C26 1 
HETATM 6137 C C27 . A1AVC F 4 .   ? 132.340 154.323 155.735 1.00 118.38 ? 801 A1AVC A C27 1 
HETATM 6138 C C28 . A1AVC F 4 .   ? 130.943 154.215 156.413 1.00 121.55 ? 801 A1AVC A C28 1 
HETATM 6139 C C29 . A1AVC F 4 .   ? 130.508 155.471 157.178 1.00 124.13 ? 801 A1AVC A C29 1 
HETATM 6140 C C30 . A1AVC F 4 .   ? 131.565 155.916 158.225 1.00 118.18 ? 801 A1AVC A C30 1 
HETATM 6141 C C31 . A1AVC F 4 .   ? 130.136 156.605 156.247 1.00 123.08 ? 801 A1AVC A C31 1 
HETATM 6142 O O32 . A1AVC F 4 .   ? 140.034 145.182 150.982 1.00 103.26 ? 801 A1AVC A O32 1 
HETATM 6143 O O33 . A1AVC F 4 .   ? 141.187 147.674 146.107 1.00 108.46 ? 801 A1AVC A O33 1 
HETATM 6144 C C22 . 6PL   G 5 .   ? 120.364 133.938 150.045 0.60 77.80  ? 802 6PL   A C22 1 
HETATM 6145 C C21 . 6PL   G 5 .   ? 121.669 133.695 150.793 0.60 81.01  ? 802 6PL   A C21 1 
HETATM 6146 C C20 . 6PL   G 5 .   ? 122.830 134.540 150.281 0.60 82.72  ? 802 6PL   A C20 1 
HETATM 6147 C C19 . 6PL   G 5 .   ? 123.228 134.221 148.844 0.60 79.35  ? 802 6PL   A C19 1 
HETATM 6148 C C18 . 6PL   G 5 .   ? 124.481 134.960 148.387 0.60 77.08  ? 802 6PL   A C18 1 
HETATM 6149 C C17 . 6PL   G 5 .   ? 124.876 134.633 146.952 0.60 75.22  ? 802 6PL   A C17 1 
HETATM 6150 C C16 . 6PL   G 5 .   ? 126.317 134.999 146.621 0.60 74.52  ? 802 6PL   A C16 1 
HETATM 6151 C C15 . 6PL   G 5 .   ? 126.619 134.978 145.127 0.60 73.71  ? 802 6PL   A C15 1 
HETATM 6152 C C14 . 6PL   G 5 .   ? 126.678 133.577 144.529 0.60 72.95  ? 802 6PL   A C14 1 
HETATM 6153 C C13 . 6PL   G 5 .   ? 126.195 133.517 143.084 0.60 69.49  ? 802 6PL   A C13 1 
HETATM 6154 C C12 . 6PL   G 5 .   ? 124.679 133.572 142.980 0.60 67.79  ? 802 6PL   A C12 1 
HETATM 6155 C C11 . 6PL   G 5 .   ? 124.168 133.632 141.570 0.60 67.56  ? 802 6PL   A C11 1 
HETATM 6156 O O11 . 6PL   G 5 .   ? 124.858 133.629 140.582 0.60 67.23  ? 802 6PL   A O11 1 
HETATM 6157 O O3  . 6PL   G 5 .   ? 122.844 133.692 141.526 0.60 69.91  ? 802 6PL   A O3  1 
HETATM 6158 C C3  . 6PL   G 5 .   ? 122.122 132.470 141.551 0.60 68.22  ? 802 6PL   A C3  1 
HETATM 6159 C C2  . 6PL   G 5 .   ? 121.608 132.164 140.160 0.60 64.09  ? 802 6PL   A C2  1 
HETATM 6160 C C1  . 6PL   G 5 .   ? 120.178 132.611 139.883 0.60 62.53  ? 802 6PL   A C1  1 
HETATM 6161 O O3P . 6PL   G 5 .   ? 120.093 134.016 139.863 0.60 63.68  ? 802 6PL   A O3P 1 
HETATM 6162 P P   . 6PL   G 5 .   ? 119.453 134.762 138.563 0.60 56.51  ? 802 6PL   A P   1 
HETATM 6163 O O1P . 6PL   G 5 .   ? 120.528 135.229 137.624 0.60 68.71  ? 802 6PL   A O1P 1 
HETATM 6164 O O2P . 6PL   G 5 .   ? 118.296 133.980 138.030 0.60 56.74  ? 802 6PL   A O2P 1 
HETATM 6165 O O4P . 6PL   G 5 .   ? 118.913 136.063 139.420 0.60 66.77  ? 802 6PL   A O4P 1 
HETATM 6166 C C4  . 6PL   G 5 .   ? 117.790 135.895 140.245 0.60 72.27  ? 802 6PL   A C4  1 
HETATM 6167 C C5  . 6PL   G 5 .   ? 117.905 136.603 141.577 0.60 73.95  ? 802 6PL   A C5  1 
HETATM 6168 N N   . 6PL   G 5 .   ? 117.939 138.113 141.628 0.60 73.85  ? 802 6PL   A N   1 
HETATM 6169 C C7  . 6PL   G 5 .   ? 116.766 138.740 140.957 0.60 74.09  ? 802 6PL   A C7  1 
HETATM 6170 C C8  . 6PL   G 5 .   ? 117.894 138.491 143.070 0.60 75.46  ? 802 6PL   A C8  1 
HETATM 6171 C C6  . 6PL   G 5 .   ? 119.192 138.672 141.042 0.60 72.28  ? 802 6PL   A C6  1 
HETATM 6172 O O2  . 6PL   G 5 .   ? 121.835 130.774 139.878 0.60 65.87  ? 802 6PL   A O2  1 
HETATM 6173 C C31 . 6PL   G 5 .   ? 121.253 129.790 140.559 0.60 72.85  ? 802 6PL   A C31 1 
HETATM 6174 O O31 . 6PL   G 5 .   ? 120.178 129.869 141.097 0.60 76.43  ? 802 6PL   A O31 1 
HETATM 6175 C C32 . 6PL   G 5 .   ? 122.132 128.569 140.565 0.60 75.25  ? 802 6PL   A C32 1 
HETATM 6176 C C33 . 6PL   G 5 .   ? 122.118 127.814 141.883 0.60 79.19  ? 802 6PL   A C33 1 
HETATM 6177 C C34 . 6PL   G 5 .   ? 123.266 126.815 141.984 0.60 81.21  ? 802 6PL   A C34 1 
HETATM 6178 C C35 . 6PL   G 5 .   ? 123.353 126.161 143.357 0.60 87.73  ? 802 6PL   A C35 1 
HETATM 6179 C C36 . 6PL   G 5 .   ? 124.669 125.433 143.610 0.60 88.56  ? 802 6PL   A C36 1 
HETATM 6180 C C37 . 6PL   G 5 .   ? 124.801 124.938 145.046 0.60 86.39  ? 802 6PL   A C37 1 
HETATM 6181 C C38 . 6PL   G 5 .   ? 123.988 123.685 145.354 0.60 89.12  ? 802 6PL   A C38 1 
HETATM 6182 C C39 . 6PL   G 5 .   ? 124.637 122.415 144.815 0.60 89.58  ? 802 6PL   A C39 1 
HETATM 6183 C C40 . 6PL   G 5 .   ? 123.925 121.133 145.226 0.60 89.88  ? 802 6PL   A C40 1 
HETATM 6184 C C41 . 6PL   G 5 .   ? 124.638 119.878 144.735 0.60 87.05  ? 802 6PL   A C41 1 
HETATM 6185 C C42 . 6PL   G 5 .   ? 123.895 118.584 145.041 0.60 84.76  ? 802 6PL   A C42 1 
HETATM 6186 C C43 . 6PL   G 5 .   ? 122.684 118.362 144.142 0.60 84.50  ? 802 6PL   A C43 1 
HETATM 6187 C C44 . 6PL   G 5 .   ? 121.973 117.035 144.379 0.60 86.17  ? 802 6PL   A C44 1 
HETATM 6188 C C45 . 6PL   G 5 .   ? 122.742 115.833 143.843 0.60 84.84  ? 802 6PL   A C45 1 
HETATM 6189 C C46 . 6PL   G 5 .   ? 121.991 114.518 143.995 0.60 78.63  ? 802 6PL   A C46 1 
HETATM 6190 C C26 . 6PL   H 5 .   ? 148.050 169.587 122.123 0.60 116.46 ? 803 6PL   A C26 1 
HETATM 6191 C C25 . 6PL   H 5 .   ? 148.916 168.464 122.678 0.60 118.00 ? 803 6PL   A C25 1 
HETATM 6192 C C24 . 6PL   H 5 .   ? 148.100 167.323 123.276 0.60 118.19 ? 803 6PL   A C24 1 
HETATM 6193 C C23 . 6PL   H 5 .   ? 147.314 166.529 122.241 0.60 116.16 ? 803 6PL   A C23 1 
HETATM 6194 C C22 . 6PL   H 5 .   ? 146.627 165.300 122.824 0.60 114.34 ? 803 6PL   A C22 1 
HETATM 6195 C C21 . 6PL   H 5 .   ? 146.031 164.380 121.765 0.60 110.91 ? 803 6PL   A C21 1 
HETATM 6196 C C20 . 6PL   H 5 .   ? 145.267 163.196 122.347 0.60 110.95 ? 803 6PL   A C20 1 
HETATM 6197 C C19 . 6PL   H 5 .   ? 146.166 162.143 122.984 0.60 111.12 ? 803 6PL   A C19 1 
HETATM 6198 C C18 . 6PL   H 5 .   ? 145.393 160.985 123.602 0.60 108.92 ? 803 6PL   A C18 1 
HETATM 6199 C C17 . 6PL   H 5 .   ? 146.231 160.160 124.572 0.60 109.35 ? 803 6PL   A C17 1 
HETATM 6200 C C16 . 6PL   H 5 .   ? 145.415 159.162 125.382 0.60 109.86 ? 803 6PL   A C16 1 
HETATM 6201 C C15 . 6PL   H 5 .   ? 146.168 158.633 126.595 0.60 108.85 ? 803 6PL   A C15 1 
HETATM 6202 C C14 . 6PL   H 5 .   ? 145.310 157.776 127.515 0.60 105.77 ? 803 6PL   A C14 1 
HETATM 6203 C C13 . 6PL   H 5 .   ? 145.979 157.516 128.858 0.60 105.14 ? 803 6PL   A C13 1 
HETATM 6204 C C12 . 6PL   H 5 .   ? 145.107 156.682 129.779 0.60 105.75 ? 803 6PL   A C12 1 
HETATM 6205 C C11 . 6PL   H 5 .   ? 145.726 156.429 131.123 0.60 107.15 ? 803 6PL   A C11 1 
HETATM 6206 O O11 . 6PL   H 5 .   ? 146.738 156.946 131.529 0.60 107.16 ? 803 6PL   A O11 1 
HETATM 6207 O O3  . 6PL   H 5 .   ? 145.017 155.550 131.823 0.60 105.10 ? 803 6PL   A O3  1 
HETATM 6208 C C3  . 6PL   H 5 .   ? 145.553 155.072 133.051 0.60 102.92 ? 803 6PL   A C3  1 
HETATM 6209 C C2  . 6PL   H 5 .   ? 145.341 156.100 134.141 0.60 102.74 ? 803 6PL   A C2  1 
HETATM 6210 C C1  . 6PL   H 5 .   ? 145.684 155.622 135.545 0.60 100.82 ? 803 6PL   A C1  1 
HETATM 6211 O O3P . 6PL   H 5 .   ? 146.572 156.528 136.157 0.60 103.14 ? 803 6PL   A O3P 1 
HETATM 6212 P P   . 6PL   H 5 .   ? 147.691 156.007 137.222 0.60 102.67 ? 803 6PL   A P   1 
HETATM 6213 O O1P . 6PL   H 5 .   ? 147.750 154.508 137.286 0.60 106.02 ? 803 6PL   A O1P 1 
HETATM 6214 O O2P . 6PL   H 5 .   ? 148.958 156.790 137.075 0.60 90.25  ? 803 6PL   A O2P 1 
HETATM 6215 O O4P . 6PL   H 5 .   ? 146.825 156.559 138.511 0.60 98.47  ? 803 6PL   A O4P 1 
HETATM 6216 C C4  . 6PL   H 5 .   ? 146.387 157.896 138.516 0.60 96.97  ? 803 6PL   A C4  1 
HETATM 6217 C C5  . 6PL   H 5 .   ? 146.172 158.441 139.911 0.60 93.47  ? 803 6PL   A C5  1 
HETATM 6218 N N   . 6PL   H 5 .   ? 147.167 158.089 140.992 0.60 93.11  ? 803 6PL   A N   1 
HETATM 6219 C C7  . 6PL   H 5 .   ? 148.566 158.092 140.484 0.60 92.63  ? 803 6PL   A C7  1 
HETATM 6220 C C8  . 6PL   H 5 .   ? 147.048 159.138 142.046 0.60 92.61  ? 803 6PL   A C8  1 
HETATM 6221 C C6  . 6PL   H 5 .   ? 146.878 156.772 141.634 0.60 92.92  ? 803 6PL   A C6  1 
HETATM 6222 O O2  . 6PL   H 5 .   ? 144.000 156.602 134.030 0.60 102.62 ? 803 6PL   A O2  1 
HETATM 6223 C C31 . 6PL   H 5 .   ? 142.950 155.782 134.045 0.60 102.54 ? 803 6PL   A C31 1 
HETATM 6224 O O31 . 6PL   H 5 .   ? 142.853 154.825 134.772 0.60 100.61 ? 803 6PL   A O31 1 
HETATM 6225 C C32 . 6PL   H 5 .   ? 141.918 156.206 133.035 0.60 100.75 ? 803 6PL   A C32 1 
HETATM 6226 C C33 . 6PL   H 5 .   ? 140.720 155.273 132.952 0.60 97.38  ? 803 6PL   A C33 1 
HETATM 6227 C C34 . 6PL   H 5 .   ? 139.703 155.742 131.918 0.60 96.30  ? 803 6PL   A C34 1 
HETATM 6228 C C35 . 6PL   H 5 .   ? 138.336 155.090 132.090 0.60 94.98  ? 803 6PL   A C35 1 
HETATM 6229 C C36 . 6PL   H 5 .   ? 138.260 153.653 131.587 0.60 93.57  ? 803 6PL   A C36 1 
HETATM 6230 C C37 . 6PL   H 5 .   ? 136.866 153.057 131.742 0.60 91.62  ? 803 6PL   A C37 1 
HETATM 6231 C C38 . 6PL   H 5 .   ? 136.543 152.595 133.159 0.60 90.45  ? 803 6PL   A C38 1 
HETATM 6232 C C39 . 6PL   H 5 .   ? 135.047 152.564 133.445 0.60 90.96  ? 803 6PL   A C39 1 
HETATM 6233 C C40 . 6PL   H 5 .   ? 134.690 151.895 134.768 0.60 89.23  ? 803 6PL   A C40 1 
HETATM 6234 C C41 . 6PL   H 5 .   ? 133.282 152.229 135.247 0.60 86.43  ? 803 6PL   A C41 1 
HETATM 6235 C C42 . 6PL   H 5 .   ? 132.178 151.779 134.297 0.60 85.51  ? 803 6PL   A C42 1 
HETATM 6236 C C43 . 6PL   H 5 .   ? 130.786 151.933 134.897 0.60 82.30  ? 803 6PL   A C43 1 
HETATM 6237 C C44 . 6PL   H 5 .   ? 129.658 151.538 133.950 0.60 83.52  ? 803 6PL   A C44 1 
HETATM 6238 C C45 . 6PL   H 5 .   ? 129.456 152.528 132.808 0.60 84.32  ? 803 6PL   A C45 1 
HETATM 6239 C C46 . 6PL   H 5 .   ? 128.220 152.240 131.967 0.60 79.42  ? 803 6PL   A C46 1 
HETATM 6240 C C1  . NAG   I 6 .   ? 191.022 138.184 139.670 1.00 109.86 ? 804 NAG   A C1  1 
HETATM 6241 C C2  . NAG   I 6 .   ? 191.119 137.590 138.276 1.00 109.57 ? 804 NAG   A C2  1 
HETATM 6242 C C3  . NAG   I 6 .   ? 190.125 138.272 137.335 1.00 109.40 ? 804 NAG   A C3  1 
HETATM 6243 C C4  . NAG   I 6 .   ? 189.796 139.688 137.798 1.00 112.07 ? 804 NAG   A C4  1 
HETATM 6244 C C5  . NAG   I 6 .   ? 189.283 139.717 139.239 1.00 112.13 ? 804 NAG   A C5  1 
HETATM 6245 C C6  . NAG   I 6 .   ? 187.776 139.779 139.328 1.00 107.70 ? 804 NAG   A C6  1 
HETATM 6246 C C7  . NAG   I 6 .   ? 193.321 136.666 137.711 1.00 108.85 ? 804 NAG   A C7  1 
HETATM 6247 C C8  . NAG   I 6 .   ? 194.677 136.955 137.142 1.00 108.07 ? 804 NAG   A C8  1 
HETATM 6248 N N2  . NAG   I 6 .   ? 192.472 137.697 137.755 1.00 107.95 ? 804 NAG   A N2  1 
HETATM 6249 O O3  . NAG   I 6 .   ? 188.934 137.496 137.264 1.00 108.72 ? 804 NAG   A O3  1 
HETATM 6250 O O4  . NAG   I 6 .   ? 190.954 140.511 137.700 1.00 109.60 ? 804 NAG   A O4  1 
HETATM 6251 O O5  . NAG   I 6 .   ? 189.690 138.534 139.939 1.00 113.20 ? 804 NAG   A O5  1 
HETATM 6252 O O6  . NAG   I 6 .   ? 187.188 140.002 138.054 1.00 106.62 ? 804 NAG   A O6  1 
HETATM 6253 O O7  . NAG   I 6 .   ? 193.008 135.549 138.112 1.00 107.05 ? 804 NAG   A O7  1 
# 
