data_9BVP
# 
_entry.id   9BVP 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BVP         pdb_00009bvp 10.2210/pdb9bvp/pdb 
WWPDB D_1000284193 ?            ?                   
EMDB  EMD-44940    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-01-22 ? 
2 'Structure model' 1 1 2025-03-12 ? 
3 'Structure model' 1 2 2025-03-19 ? 
4 'Structure model' 1 3 2025-03-26 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
3 3 'Structure model' 'Data collection'     
4 4 'Structure model' 'Data collection'     
5 4 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
4 3 'Structure model' em_admin        
5 4 'Structure model' citation        
6 4 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_ASTM'         
4  2 'Structure model' '_citation.journal_id_CSD'          
5  2 'Structure model' '_citation.journal_id_ISSN'         
6  2 'Structure model' '_citation.pdbx_database_id_DOI'    
7  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
8  2 'Structure model' '_citation.title'                   
9  2 'Structure model' '_citation.year'                    
10 2 'Structure model' '_em_admin.last_update'             
11 3 'Structure model' '_em_admin.last_update'             
12 4 'Structure model' '_citation.journal_volume'          
13 4 'Structure model' '_citation.page_first'              
14 4 'Structure model' '_citation.page_last'               
15 4 'Structure model' '_citation.title'                   
16 4 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BVP 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Vitamin K-dependent gamma-carboxylase with TMG2 propeptide and glutamate-rich region and with vitamin K hydroquinone' 
_pdbx_database_related.db_id          EMD-44940 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              weikai@wustl.edu 
_pdbx_contact_author.name_first         Weikai 
_pdbx_contact_author.name_last          Li 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-8711-1904 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Li, W.'  1 0000-0002-8711-1904 
'Liu, B.' 2 0000-0002-6581-780X 
'Cao, Q.' 3 0000-0003-2517-2231 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Nature 
_citation.journal_id_ASTM           NATUAS 
_citation.journal_id_CSD            0006 
_citation.journal_id_ISSN           1476-4687 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            639 
_citation.language                  ? 
_citation.page_first                816 
_citation.page_last                 824 
_citation.title                     'Molecular basis of vitamin-K-driven gamma-carboxylation at the membrane interface.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41586-025-08648-1 
_citation.pdbx_database_id_PubMed   39880037 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Cao, Q.'      1  0000-0003-2517-2231 
primary 'Ammerman, A.' 2  0000-0001-9245-4015 
primary 'Saimi, M.'    3  ?                   
primary 'Lin, Z.'      4  ?                   
primary 'Shen, G.'     5  0000-0002-5006-2790 
primary 'Chen, H.'     6  0000-0002-9835-5138 
primary 'Sun, J.'      7  0000-0001-8775-5032 
primary 'Chai, M.'     8  ?                   
primary 'Liu, S.'      9  ?                   
primary 'Hsu, F.F.'    10 ?                   
primary 'Krezel, A.M.' 11 ?                   
primary 'Gross, M.L.'  12 0000-0003-1159-4636 
primary 'Xu, J.'       13 0000-0002-2120-8287 
primary 'Garcia, B.A.' 14 0000-0003-3596-4750 
primary 'Liu, B.'      15 0000-0002-6581-780X 
primary 'Li, W.'       16 0000-0002-8711-1904 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Vitamin K-dependent gamma-carboxylase' 85092.758 1 4.1.1.90 ? ? ? 
2 polymer     man 'Transmembrane gamma-carboxyglutamic acid protein 2' 13399.892 1 ?        ? ? ? 
3 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   3 ?        ? 
? ? 
4 non-polymer syn 'vitamin K1 hydroquinone' 452.712   1 ?        ? ? ? 
5 non-polymer syn 
'(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE' 763.100   2 ? 
? ? ? 
6 non-polymer man 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208   1 ?        ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Gamma-glutamyl carboxylase,Peptidyl-glutamate 4-carboxylase,Vitamin K gamma glutamyl carboxylase' 
2 'Proline-rich gamma-carboxyglutamic acid protein 2,Proline-rich Gla protein 2'                     
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;SGPRQDSRIGKLLGFEWTDLSSWRRLVTLLNRPTDPASLAVFRFLFGFLMVLDIPQERGLSSLDRKYLDGLDVCRFPLLD
ALRPLPLDWMYLVYTIMFLGALGMMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGL
LNAHRRNAHVPLWNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKLLLSEELTSLLVVHWGGLLLDLS
AGFLLFFDVSRSIGLFFVSYFHCMNSQLFSIGMFSYVMLASSPLFCSPEWPRKLVSYCPRRLQQLLPLKAAPQPSVSCVY
KRSRGKSGQKPGLRHQLGAAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGY
LNPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAAWSPFQRTSWVQPL
LMDLSPWRAKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGE
YHKVYTTSPSPSCYMYVYVNTTELALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQR
LQEIERRRNTPFHERFFRFLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGELNPSNTDSSHSN
PPESNPDPVHSEF
;
;SGPRQDSRIGKLLGFEWTDLSSWRRLVTLLNRPTDPASLAVFRFLFGFLMVLDIPQERGLSSLDRKYLDGLDVCRFPLLD
ALRPLPLDWMYLVYTIMFLGALGMMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGL
LNAHRRNAHVPLWNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKLLLSEELTSLLVVHWGGLLLDLS
AGFLLFFDVSRSIGLFFVSYFHCMNSQLFSIGMFSYVMLASSPLFCSPEWPRKLVSYCPRRLQQLLPLKAAPQPSVSCVY
KRSRGKSGQKPGLRHQLGAAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGY
LNPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAAWSPFQRTSWVQPL
LMDLSPWRAKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGE
YHKVYTTSPSPSCYMYVYVNTTELALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQR
LQEIERRRNTPFHERFFRFLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGELNPSNTDSSHSN
PPESNPDPVHSEF
;
A ? 
2 'polypeptide(L)' no no 
;EETDQEVFLGPPEAQSFLSSHTRIPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYIYNGKGGRG
RVDVASLAVGLTGGILLIVLAGLGAFWYLRWRQHRG
;
;EETDQEVFLGPPEAQSFLSSHTRIPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYIYNGKGGRG
RVDVASLAVGLTGGILLIVLAGLGAFWYLRWRQHRG
;
P ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 'vitamin K1 hydroquinone'                                                                                            A1AVC 
5 '(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE' 6PL   
6 2-acetamido-2-deoxy-beta-D-glucopyranose                                                                             NAG   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   GLY n 
1 3   PRO n 
1 4   ARG n 
1 5   GLN n 
1 6   ASP n 
1 7   SER n 
1 8   ARG n 
1 9   ILE n 
1 10  GLY n 
1 11  LYS n 
1 12  LEU n 
1 13  LEU n 
1 14  GLY n 
1 15  PHE n 
1 16  GLU n 
1 17  TRP n 
1 18  THR n 
1 19  ASP n 
1 20  LEU n 
1 21  SER n 
1 22  SER n 
1 23  TRP n 
1 24  ARG n 
1 25  ARG n 
1 26  LEU n 
1 27  VAL n 
1 28  THR n 
1 29  LEU n 
1 30  LEU n 
1 31  ASN n 
1 32  ARG n 
1 33  PRO n 
1 34  THR n 
1 35  ASP n 
1 36  PRO n 
1 37  ALA n 
1 38  SER n 
1 39  LEU n 
1 40  ALA n 
1 41  VAL n 
1 42  PHE n 
1 43  ARG n 
1 44  PHE n 
1 45  LEU n 
1 46  PHE n 
1 47  GLY n 
1 48  PHE n 
1 49  LEU n 
1 50  MET n 
1 51  VAL n 
1 52  LEU n 
1 53  ASP n 
1 54  ILE n 
1 55  PRO n 
1 56  GLN n 
1 57  GLU n 
1 58  ARG n 
1 59  GLY n 
1 60  LEU n 
1 61  SER n 
1 62  SER n 
1 63  LEU n 
1 64  ASP n 
1 65  ARG n 
1 66  LYS n 
1 67  TYR n 
1 68  LEU n 
1 69  ASP n 
1 70  GLY n 
1 71  LEU n 
1 72  ASP n 
1 73  VAL n 
1 74  CYS n 
1 75  ARG n 
1 76  PHE n 
1 77  PRO n 
1 78  LEU n 
1 79  LEU n 
1 80  ASP n 
1 81  ALA n 
1 82  LEU n 
1 83  ARG n 
1 84  PRO n 
1 85  LEU n 
1 86  PRO n 
1 87  LEU n 
1 88  ASP n 
1 89  TRP n 
1 90  MET n 
1 91  TYR n 
1 92  LEU n 
1 93  VAL n 
1 94  TYR n 
1 95  THR n 
1 96  ILE n 
1 97  MET n 
1 98  PHE n 
1 99  LEU n 
1 100 GLY n 
1 101 ALA n 
1 102 LEU n 
1 103 GLY n 
1 104 MET n 
1 105 MET n 
1 106 LEU n 
1 107 GLY n 
1 108 LEU n 
1 109 CYS n 
1 110 TYR n 
1 111 ARG n 
1 112 ILE n 
1 113 SER n 
1 114 CYS n 
1 115 VAL n 
1 116 LEU n 
1 117 PHE n 
1 118 LEU n 
1 119 LEU n 
1 120 PRO n 
1 121 TYR n 
1 122 TRP n 
1 123 TYR n 
1 124 VAL n 
1 125 PHE n 
1 126 LEU n 
1 127 LEU n 
1 128 ASP n 
1 129 LYS n 
1 130 THR n 
1 131 SER n 
1 132 TRP n 
1 133 ASN n 
1 134 ASN n 
1 135 HIS n 
1 136 SER n 
1 137 TYR n 
1 138 LEU n 
1 139 TYR n 
1 140 GLY n 
1 141 LEU n 
1 142 LEU n 
1 143 ALA n 
1 144 PHE n 
1 145 GLN n 
1 146 LEU n 
1 147 THR n 
1 148 PHE n 
1 149 MET n 
1 150 ASP n 
1 151 ALA n 
1 152 ASN n 
1 153 HIS n 
1 154 TYR n 
1 155 TRP n 
1 156 SER n 
1 157 VAL n 
1 158 ASP n 
1 159 GLY n 
1 160 LEU n 
1 161 LEU n 
1 162 ASN n 
1 163 ALA n 
1 164 HIS n 
1 165 ARG n 
1 166 ARG n 
1 167 ASN n 
1 168 ALA n 
1 169 HIS n 
1 170 VAL n 
1 171 PRO n 
1 172 LEU n 
1 173 TRP n 
1 174 ASN n 
1 175 TYR n 
1 176 ALA n 
1 177 VAL n 
1 178 LEU n 
1 179 ARG n 
1 180 GLY n 
1 181 GLN n 
1 182 ILE n 
1 183 PHE n 
1 184 ILE n 
1 185 VAL n 
1 186 TYR n 
1 187 PHE n 
1 188 ILE n 
1 189 ALA n 
1 190 GLY n 
1 191 VAL n 
1 192 LYS n 
1 193 LYS n 
1 194 LEU n 
1 195 ASP n 
1 196 ALA n 
1 197 ASP n 
1 198 TRP n 
1 199 VAL n 
1 200 GLU n 
1 201 GLY n 
1 202 TYR n 
1 203 SER n 
1 204 MET n 
1 205 GLU n 
1 206 TYR n 
1 207 LEU n 
1 208 SER n 
1 209 ARG n 
1 210 HIS n 
1 211 TRP n 
1 212 LEU n 
1 213 PHE n 
1 214 SER n 
1 215 PRO n 
1 216 PHE n 
1 217 LYS n 
1 218 LEU n 
1 219 LEU n 
1 220 LEU n 
1 221 SER n 
1 222 GLU n 
1 223 GLU n 
1 224 LEU n 
1 225 THR n 
1 226 SER n 
1 227 LEU n 
1 228 LEU n 
1 229 VAL n 
1 230 VAL n 
1 231 HIS n 
1 232 TRP n 
1 233 GLY n 
1 234 GLY n 
1 235 LEU n 
1 236 LEU n 
1 237 LEU n 
1 238 ASP n 
1 239 LEU n 
1 240 SER n 
1 241 ALA n 
1 242 GLY n 
1 243 PHE n 
1 244 LEU n 
1 245 LEU n 
1 246 PHE n 
1 247 PHE n 
1 248 ASP n 
1 249 VAL n 
1 250 SER n 
1 251 ARG n 
1 252 SER n 
1 253 ILE n 
1 254 GLY n 
1 255 LEU n 
1 256 PHE n 
1 257 PHE n 
1 258 VAL n 
1 259 SER n 
1 260 TYR n 
1 261 PHE n 
1 262 HIS n 
1 263 CYS n 
1 264 MET n 
1 265 ASN n 
1 266 SER n 
1 267 GLN n 
1 268 LEU n 
1 269 PHE n 
1 270 SER n 
1 271 ILE n 
1 272 GLY n 
1 273 MET n 
1 274 PHE n 
1 275 SER n 
1 276 TYR n 
1 277 VAL n 
1 278 MET n 
1 279 LEU n 
1 280 ALA n 
1 281 SER n 
1 282 SER n 
1 283 PRO n 
1 284 LEU n 
1 285 PHE n 
1 286 CYS n 
1 287 SER n 
1 288 PRO n 
1 289 GLU n 
1 290 TRP n 
1 291 PRO n 
1 292 ARG n 
1 293 LYS n 
1 294 LEU n 
1 295 VAL n 
1 296 SER n 
1 297 TYR n 
1 298 CYS n 
1 299 PRO n 
1 300 ARG n 
1 301 ARG n 
1 302 LEU n 
1 303 GLN n 
1 304 GLN n 
1 305 LEU n 
1 306 LEU n 
1 307 PRO n 
1 308 LEU n 
1 309 LYS n 
1 310 ALA n 
1 311 ALA n 
1 312 PRO n 
1 313 GLN n 
1 314 PRO n 
1 315 SER n 
1 316 VAL n 
1 317 SER n 
1 318 CYS n 
1 319 VAL n 
1 320 TYR n 
1 321 LYS n 
1 322 ARG n 
1 323 SER n 
1 324 ARG n 
1 325 GLY n 
1 326 LYS n 
1 327 SER n 
1 328 GLY n 
1 329 GLN n 
1 330 LYS n 
1 331 PRO n 
1 332 GLY n 
1 333 LEU n 
1 334 ARG n 
1 335 HIS n 
1 336 GLN n 
1 337 LEU n 
1 338 GLY n 
1 339 ALA n 
1 340 ALA n 
1 341 PHE n 
1 342 THR n 
1 343 LEU n 
1 344 LEU n 
1 345 TYR n 
1 346 LEU n 
1 347 LEU n 
1 348 GLU n 
1 349 GLN n 
1 350 LEU n 
1 351 PHE n 
1 352 LEU n 
1 353 PRO n 
1 354 TYR n 
1 355 SER n 
1 356 HIS n 
1 357 PHE n 
1 358 LEU n 
1 359 THR n 
1 360 GLN n 
1 361 GLY n 
1 362 TYR n 
1 363 ASN n 
1 364 ASN n 
1 365 TRP n 
1 366 THR n 
1 367 ASN n 
1 368 GLY n 
1 369 LEU n 
1 370 TYR n 
1 371 GLY n 
1 372 TYR n 
1 373 SER n 
1 374 TRP n 
1 375 ASP n 
1 376 MET n 
1 377 MET n 
1 378 VAL n 
1 379 HIS n 
1 380 SER n 
1 381 ARG n 
1 382 SER n 
1 383 HIS n 
1 384 GLN n 
1 385 HIS n 
1 386 VAL n 
1 387 LYS n 
1 388 ILE n 
1 389 THR n 
1 390 TYR n 
1 391 ARG n 
1 392 ASP n 
1 393 GLY n 
1 394 ARG n 
1 395 THR n 
1 396 GLY n 
1 397 GLU n 
1 398 LEU n 
1 399 GLY n 
1 400 TYR n 
1 401 LEU n 
1 402 ASN n 
1 403 PRO n 
1 404 GLY n 
1 405 VAL n 
1 406 PHE n 
1 407 THR n 
1 408 GLN n 
1 409 SER n 
1 410 ARG n 
1 411 ARG n 
1 412 TRP n 
1 413 LYS n 
1 414 ASP n 
1 415 HIS n 
1 416 ALA n 
1 417 ASP n 
1 418 MET n 
1 419 LEU n 
1 420 LYS n 
1 421 GLN n 
1 422 TYR n 
1 423 ALA n 
1 424 THR n 
1 425 CYS n 
1 426 LEU n 
1 427 SER n 
1 428 ARG n 
1 429 LEU n 
1 430 LEU n 
1 431 PRO n 
1 432 LYS n 
1 433 TYR n 
1 434 ASN n 
1 435 VAL n 
1 436 THR n 
1 437 GLU n 
1 438 PRO n 
1 439 GLN n 
1 440 ILE n 
1 441 TYR n 
1 442 PHE n 
1 443 ASP n 
1 444 ILE n 
1 445 TRP n 
1 446 VAL n 
1 447 SER n 
1 448 ILE n 
1 449 ASN n 
1 450 ASP n 
1 451 ARG n 
1 452 PHE n 
1 453 GLN n 
1 454 GLN n 
1 455 ARG n 
1 456 ILE n 
1 457 PHE n 
1 458 ASP n 
1 459 PRO n 
1 460 ARG n 
1 461 VAL n 
1 462 ASP n 
1 463 ILE n 
1 464 VAL n 
1 465 GLN n 
1 466 ALA n 
1 467 ALA n 
1 468 TRP n 
1 469 SER n 
1 470 PRO n 
1 471 PHE n 
1 472 GLN n 
1 473 ARG n 
1 474 THR n 
1 475 SER n 
1 476 TRP n 
1 477 VAL n 
1 478 GLN n 
1 479 PRO n 
1 480 LEU n 
1 481 LEU n 
1 482 MET n 
1 483 ASP n 
1 484 LEU n 
1 485 SER n 
1 486 PRO n 
1 487 TRP n 
1 488 ARG n 
1 489 ALA n 
1 490 LYS n 
1 491 LEU n 
1 492 GLN n 
1 493 GLU n 
1 494 ILE n 
1 495 LYS n 
1 496 SER n 
1 497 SER n 
1 498 LEU n 
1 499 ASP n 
1 500 ASN n 
1 501 HIS n 
1 502 THR n 
1 503 GLU n 
1 504 VAL n 
1 505 VAL n 
1 506 PHE n 
1 507 ILE n 
1 508 ALA n 
1 509 ASP n 
1 510 PHE n 
1 511 PRO n 
1 512 GLY n 
1 513 LEU n 
1 514 HIS n 
1 515 LEU n 
1 516 GLU n 
1 517 ASN n 
1 518 PHE n 
1 519 VAL n 
1 520 SER n 
1 521 GLU n 
1 522 ASP n 
1 523 LEU n 
1 524 GLY n 
1 525 ASN n 
1 526 THR n 
1 527 SER n 
1 528 ILE n 
1 529 GLN n 
1 530 LEU n 
1 531 LEU n 
1 532 GLN n 
1 533 GLY n 
1 534 GLU n 
1 535 VAL n 
1 536 THR n 
1 537 VAL n 
1 538 GLU n 
1 539 LEU n 
1 540 VAL n 
1 541 ALA n 
1 542 GLU n 
1 543 GLN n 
1 544 LYS n 
1 545 ASN n 
1 546 GLN n 
1 547 THR n 
1 548 LEU n 
1 549 ARG n 
1 550 GLU n 
1 551 GLY n 
1 552 GLU n 
1 553 LYS n 
1 554 MET n 
1 555 GLN n 
1 556 LEU n 
1 557 PRO n 
1 558 ALA n 
1 559 GLY n 
1 560 GLU n 
1 561 TYR n 
1 562 HIS n 
1 563 LYS n 
1 564 VAL n 
1 565 TYR n 
1 566 THR n 
1 567 THR n 
1 568 SER n 
1 569 PRO n 
1 570 SER n 
1 571 PRO n 
1 572 SER n 
1 573 CYS n 
1 574 TYR n 
1 575 MET n 
1 576 TYR n 
1 577 VAL n 
1 578 TYR n 
1 579 VAL n 
1 580 ASN n 
1 581 THR n 
1 582 THR n 
1 583 GLU n 
1 584 LEU n 
1 585 ALA n 
1 586 LEU n 
1 587 GLU n 
1 588 GLN n 
1 589 ASP n 
1 590 LEU n 
1 591 ALA n 
1 592 TYR n 
1 593 LEU n 
1 594 GLN n 
1 595 GLU n 
1 596 LEU n 
1 597 LYS n 
1 598 GLU n 
1 599 LYS n 
1 600 VAL n 
1 601 GLU n 
1 602 ASN n 
1 603 GLY n 
1 604 SER n 
1 605 GLU n 
1 606 THR n 
1 607 GLY n 
1 608 PRO n 
1 609 LEU n 
1 610 PRO n 
1 611 PRO n 
1 612 GLU n 
1 613 LEU n 
1 614 GLN n 
1 615 PRO n 
1 616 LEU n 
1 617 LEU n 
1 618 GLU n 
1 619 GLY n 
1 620 GLU n 
1 621 VAL n 
1 622 LYS n 
1 623 GLY n 
1 624 GLY n 
1 625 PRO n 
1 626 GLU n 
1 627 PRO n 
1 628 THR n 
1 629 PRO n 
1 630 LEU n 
1 631 VAL n 
1 632 GLN n 
1 633 THR n 
1 634 PHE n 
1 635 LEU n 
1 636 ARG n 
1 637 ARG n 
1 638 GLN n 
1 639 GLN n 
1 640 ARG n 
1 641 LEU n 
1 642 GLN n 
1 643 GLU n 
1 644 ILE n 
1 645 GLU n 
1 646 ARG n 
1 647 ARG n 
1 648 ARG n 
1 649 ASN n 
1 650 THR n 
1 651 PRO n 
1 652 PHE n 
1 653 HIS n 
1 654 GLU n 
1 655 ARG n 
1 656 PHE n 
1 657 PHE n 
1 658 ARG n 
1 659 PHE n 
1 660 LEU n 
1 661 LEU n 
1 662 ARG n 
1 663 LYS n 
1 664 LEU n 
1 665 TYR n 
1 666 VAL n 
1 667 PHE n 
1 668 ARG n 
1 669 ARG n 
1 670 SER n 
1 671 PHE n 
1 672 LEU n 
1 673 MET n 
1 674 THR n 
1 675 CYS n 
1 676 ILE n 
1 677 SER n 
1 678 LEU n 
1 679 ARG n 
1 680 ASN n 
1 681 LEU n 
1 682 ILE n 
1 683 LEU n 
1 684 GLY n 
1 685 ARG n 
1 686 PRO n 
1 687 SER n 
1 688 LEU n 
1 689 GLU n 
1 690 GLN n 
1 691 LEU n 
1 692 ALA n 
1 693 GLN n 
1 694 GLU n 
1 695 VAL n 
1 696 THR n 
1 697 TYR n 
1 698 ALA n 
1 699 ASN n 
1 700 LEU n 
1 701 ARG n 
1 702 PRO n 
1 703 PHE n 
1 704 GLU n 
1 705 ALA n 
1 706 VAL n 
1 707 GLY n 
1 708 GLU n 
1 709 LEU n 
1 710 ASN n 
1 711 PRO n 
1 712 SER n 
1 713 ASN n 
1 714 THR n 
1 715 ASP n 
1 716 SER n 
1 717 SER n 
1 718 HIS n 
1 719 SER n 
1 720 ASN n 
1 721 PRO n 
1 722 PRO n 
1 723 GLU n 
1 724 SER n 
1 725 ASN n 
1 726 PRO n 
1 727 ASP n 
1 728 PRO n 
1 729 VAL n 
1 730 HIS n 
1 731 SER n 
1 732 GLU n 
1 733 PHE n 
2 1   GLU n 
2 2   GLU n 
2 3   THR n 
2 4   ASP n 
2 5   GLN n 
2 6   GLU n 
2 7   VAL n 
2 8   PHE n 
2 9   LEU n 
2 10  GLY n 
2 11  PRO n 
2 12  PRO n 
2 13  GLU n 
2 14  ALA n 
2 15  GLN n 
2 16  SER n 
2 17  PHE n 
2 18  LEU n 
2 19  SER n 
2 20  SER n 
2 21  HIS n 
2 22  THR n 
2 23  ARG n 
2 24  ILE n 
2 25  PRO n 
2 26  ARG n 
2 27  ALA n 
2 28  ASN n 
2 29  HIS n 
2 30  TRP n 
2 31  ASP n 
2 32  LEU n 
2 33  GLU n 
2 34  LEU n 
2 35  LEU n 
2 36  THR n 
2 37  PRO n 
2 38  GLY n 
2 39  ASN n 
2 40  LEU n 
2 41  GLU n 
2 42  ARG n 
2 43  GLU n 
2 44  CYS n 
2 45  LEU n 
2 46  GLU n 
2 47  GLU n 
2 48  ARG n 
2 49  CYS n 
2 50  SER n 
2 51  TRP n 
2 52  GLU n 
2 53  GLU n 
2 54  ALA n 
2 55  ARG n 
2 56  GLU n 
2 57  TYR n 
2 58  PHE n 
2 59  GLU n 
2 60  ASP n 
2 61  ASN n 
2 62  THR n 
2 63  LEU n 
2 64  THR n 
2 65  GLU n 
2 66  ARG n 
2 67  PHE n 
2 68  TRP n 
2 69  GLU n 
2 70  SER n 
2 71  TYR n 
2 72  ILE n 
2 73  TYR n 
2 74  ASN n 
2 75  GLY n 
2 76  LYS n 
2 77  GLY n 
2 78  GLY n 
2 79  ARG n 
2 80  GLY n 
2 81  ARG n 
2 82  VAL n 
2 83  ASP n 
2 84  VAL n 
2 85  ALA n 
2 86  SER n 
2 87  LEU n 
2 88  ALA n 
2 89  VAL n 
2 90  GLY n 
2 91  LEU n 
2 92  THR n 
2 93  GLY n 
2 94  GLY n 
2 95  ILE n 
2 96  LEU n 
2 97  LEU n 
2 98  ILE n 
2 99  VAL n 
2 100 LEU n 
2 101 ALA n 
2 102 GLY n 
2 103 LEU n 
2 104 GLY n 
2 105 ALA n 
2 106 PHE n 
2 107 TRP n 
2 108 TYR n 
2 109 LEU n 
2 110 ARG n 
2 111 TRP n 
2 112 ARG n 
2 113 GLN n 
2 114 HIS n 
2 115 ARG n 
2 116 GLY n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 733 human ? 'GGCX, GC'           ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 
9606 ? ? ? ? ? ? ? ? HEK293S ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 116 human ? 'PRRG2, PRGP2, TMG2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 
9606 ? ? ? ? ? ? ? ? HEK293S ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   3 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 3 DGlcpNAcb1-4DGlcpNAcb1-ROH                            'Glycam Condensed Sequence' GMML       1.0   
2 3 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1' WURCS                       PDB2Glycan 1.1.0 
3 3 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}'       LINUCS                      PDB-CARE   ?     
# 
_pdbx_entity_branch_link.link_id                    1 
_pdbx_entity_branch_link.entity_id                  3 
_pdbx_entity_branch_link.entity_branch_list_num_1   2 
_pdbx_entity_branch_link.comp_id_1                  NAG 
_pdbx_entity_branch_link.atom_id_1                  C1 
_pdbx_entity_branch_link.leaving_atom_id_1          O1 
_pdbx_entity_branch_link.entity_branch_list_num_2   1 
_pdbx_entity_branch_link.comp_id_2                  NAG 
_pdbx_entity_branch_link.atom_id_2                  O4 
_pdbx_entity_branch_link.leaving_atom_id_2          HO4 
_pdbx_entity_branch_link.value_order                sing 
_pdbx_entity_branch_link.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
6PL   non-polymer                  . 
'(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE' 
1-PALMITOYL-2-STEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE 'C42 H85 N O8 P 1' 763.100 
A1AVC non-polymer                  . 'vitamin K1 hydroquinone' 
'2-methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]naphthalene-1,4-diol' 'C31 H48 O2'       452.712 
ALA   'L-peptide linking'          y ALANINE ? 'C3 H7 N O2'       89.093  
ARG   'L-peptide linking'          y ARGININE ? 'C6 H15 N4 O2 1'   175.209 
ASN   'L-peptide linking'          y ASPARAGINE ? 'C4 H8 N2 O3'      132.118 
ASP   'L-peptide linking'          y 'ASPARTIC ACID' ? 'C4 H7 N O4'       133.103 
CYS   'L-peptide linking'          y CYSTEINE ? 'C3 H7 N O2 S'     121.158 
GLN   'L-peptide linking'          y GLUTAMINE ? 'C5 H10 N2 O3'     146.144 
GLU   'L-peptide linking'          y 'GLUTAMIC ACID' ? 'C5 H9 N O4'       147.129 
GLY   'peptide linking'            y GLYCINE ? 'C2 H5 N O2'       75.067  
HIS   'L-peptide linking'          y HISTIDINE ? 'C6 H10 N3 O2 1'   156.162 
ILE   'L-peptide linking'          y ISOLEUCINE ? 'C6 H13 N O2'      131.173 
LEU   'L-peptide linking'          y LEUCINE ? 'C6 H13 N O2'      131.173 
LYS   'L-peptide linking'          y LYSINE ? 'C6 H15 N2 O2 1'   147.195 
MET   'L-peptide linking'          y METHIONINE ? 'C5 H11 N O2 S'    149.211 
NAG   'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'      221.208 
PHE   'L-peptide linking'          y PHENYLALANINE ? 'C9 H11 N O2'      165.189 
PRO   'L-peptide linking'          y PROLINE ? 'C5 H9 N O2'       115.130 
SER   'L-peptide linking'          y SERINE ? 'C3 H7 N O3'       105.093 
THR   'L-peptide linking'          y THREONINE ? 'C4 H9 N O3'       119.119 
TRP   'L-peptide linking'          y TRYPTOPHAN ? 'C11 H12 N2 O2'    204.225 
TYR   'L-peptide linking'          y TYROSINE ? 'C9 H11 N O3'      181.189 
VAL   'L-peptide linking'          y VALINE ? 'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   26  ?   ?   ?   A . n 
A 1 2   GLY 2   27  ?   ?   ?   A . n 
A 1 3   PRO 3   28  ?   ?   ?   A . n 
A 1 4   ARG 4   29  ?   ?   ?   A . n 
A 1 5   GLN 5   30  ?   ?   ?   A . n 
A 1 6   ASP 6   31  31  ASP ASP A . n 
A 1 7   SER 7   32  32  SER SER A . n 
A 1 8   ARG 8   33  33  ARG ARG A . n 
A 1 9   ILE 9   34  34  ILE ILE A . n 
A 1 10  GLY 10  35  35  GLY GLY A . n 
A 1 11  LYS 11  36  36  LYS LYS A . n 
A 1 12  LEU 12  37  37  LEU LEU A . n 
A 1 13  LEU 13  38  38  LEU LEU A . n 
A 1 14  GLY 14  39  39  GLY GLY A . n 
A 1 15  PHE 15  40  40  PHE PHE A . n 
A 1 16  GLU 16  41  41  GLU GLU A . n 
A 1 17  TRP 17  42  42  TRP TRP A . n 
A 1 18  THR 18  43  43  THR THR A . n 
A 1 19  ASP 19  44  44  ASP ASP A . n 
A 1 20  LEU 20  45  45  LEU LEU A . n 
A 1 21  SER 21  46  46  SER SER A . n 
A 1 22  SER 22  47  47  SER SER A . n 
A 1 23  TRP 23  48  48  TRP TRP A . n 
A 1 24  ARG 24  49  49  ARG ARG A . n 
A 1 25  ARG 25  50  50  ARG ARG A . n 
A 1 26  LEU 26  51  51  LEU LEU A . n 
A 1 27  VAL 27  52  52  VAL VAL A . n 
A 1 28  THR 28  53  53  THR THR A . n 
A 1 29  LEU 29  54  54  LEU LEU A . n 
A 1 30  LEU 30  55  55  LEU LEU A . n 
A 1 31  ASN 31  56  56  ASN ASN A . n 
A 1 32  ARG 32  57  57  ARG ARG A . n 
A 1 33  PRO 33  58  58  PRO PRO A . n 
A 1 34  THR 34  59  59  THR THR A . n 
A 1 35  ASP 35  60  60  ASP ASP A . n 
A 1 36  PRO 36  61  61  PRO PRO A . n 
A 1 37  ALA 37  62  62  ALA ALA A . n 
A 1 38  SER 38  63  63  SER SER A . n 
A 1 39  LEU 39  64  64  LEU LEU A . n 
A 1 40  ALA 40  65  65  ALA ALA A . n 
A 1 41  VAL 41  66  66  VAL VAL A . n 
A 1 42  PHE 42  67  67  PHE PHE A . n 
A 1 43  ARG 43  68  68  ARG ARG A . n 
A 1 44  PHE 44  69  69  PHE PHE A . n 
A 1 45  LEU 45  70  70  LEU LEU A . n 
A 1 46  PHE 46  71  71  PHE PHE A . n 
A 1 47  GLY 47  72  72  GLY GLY A . n 
A 1 48  PHE 48  73  73  PHE PHE A . n 
A 1 49  LEU 49  74  74  LEU LEU A . n 
A 1 50  MET 50  75  75  MET MET A . n 
A 1 51  VAL 51  76  76  VAL VAL A . n 
A 1 52  LEU 52  77  77  LEU LEU A . n 
A 1 53  ASP 53  78  78  ASP ASP A . n 
A 1 54  ILE 54  79  79  ILE ILE A . n 
A 1 55  PRO 55  80  80  PRO PRO A . n 
A 1 56  GLN 56  81  81  GLN GLN A . n 
A 1 57  GLU 57  82  82  GLU GLU A . n 
A 1 58  ARG 58  83  83  ARG ARG A . n 
A 1 59  GLY 59  84  84  GLY GLY A . n 
A 1 60  LEU 60  85  85  LEU LEU A . n 
A 1 61  SER 61  86  86  SER SER A . n 
A 1 62  SER 62  87  87  SER SER A . n 
A 1 63  LEU 63  88  88  LEU LEU A . n 
A 1 64  ASP 64  89  89  ASP ASP A . n 
A 1 65  ARG 65  90  90  ARG ARG A . n 
A 1 66  LYS 66  91  91  LYS LYS A . n 
A 1 67  TYR 67  92  92  TYR TYR A . n 
A 1 68  LEU 68  93  93  LEU LEU A . n 
A 1 69  ASP 69  94  94  ASP ASP A . n 
A 1 70  GLY 70  95  95  GLY GLY A . n 
A 1 71  LEU 71  96  96  LEU LEU A . n 
A 1 72  ASP 72  97  97  ASP ASP A . n 
A 1 73  VAL 73  98  98  VAL VAL A . n 
A 1 74  CYS 74  99  99  CYS CYS A . n 
A 1 75  ARG 75  100 100 ARG ARG A . n 
A 1 76  PHE 76  101 101 PHE PHE A . n 
A 1 77  PRO 77  102 102 PRO PRO A . n 
A 1 78  LEU 78  103 103 LEU LEU A . n 
A 1 79  LEU 79  104 104 LEU LEU A . n 
A 1 80  ASP 80  105 105 ASP ASP A . n 
A 1 81  ALA 81  106 106 ALA ALA A . n 
A 1 82  LEU 82  107 107 LEU LEU A . n 
A 1 83  ARG 83  108 108 ARG ARG A . n 
A 1 84  PRO 84  109 109 PRO PRO A . n 
A 1 85  LEU 85  110 110 LEU LEU A . n 
A 1 86  PRO 86  111 111 PRO PRO A . n 
A 1 87  LEU 87  112 112 LEU LEU A . n 
A 1 88  ASP 88  113 113 ASP ASP A . n 
A 1 89  TRP 89  114 114 TRP TRP A . n 
A 1 90  MET 90  115 115 MET MET A . n 
A 1 91  TYR 91  116 116 TYR TYR A . n 
A 1 92  LEU 92  117 117 LEU LEU A . n 
A 1 93  VAL 93  118 118 VAL VAL A . n 
A 1 94  TYR 94  119 119 TYR TYR A . n 
A 1 95  THR 95  120 120 THR THR A . n 
A 1 96  ILE 96  121 121 ILE ILE A . n 
A 1 97  MET 97  122 122 MET MET A . n 
A 1 98  PHE 98  123 123 PHE PHE A . n 
A 1 99  LEU 99  124 124 LEU LEU A . n 
A 1 100 GLY 100 125 125 GLY GLY A . n 
A 1 101 ALA 101 126 126 ALA ALA A . n 
A 1 102 LEU 102 127 127 LEU LEU A . n 
A 1 103 GLY 103 128 128 GLY GLY A . n 
A 1 104 MET 104 129 129 MET MET A . n 
A 1 105 MET 105 130 130 MET MET A . n 
A 1 106 LEU 106 131 131 LEU LEU A . n 
A 1 107 GLY 107 132 132 GLY GLY A . n 
A 1 108 LEU 108 133 133 LEU LEU A . n 
A 1 109 CYS 109 134 134 CYS CYS A . n 
A 1 110 TYR 110 135 135 TYR TYR A . n 
A 1 111 ARG 111 136 136 ARG ARG A . n 
A 1 112 ILE 112 137 137 ILE ILE A . n 
A 1 113 SER 113 138 138 SER SER A . n 
A 1 114 CYS 114 139 139 CYS CYS A . n 
A 1 115 VAL 115 140 140 VAL VAL A . n 
A 1 116 LEU 116 141 141 LEU LEU A . n 
A 1 117 PHE 117 142 142 PHE PHE A . n 
A 1 118 LEU 118 143 143 LEU LEU A . n 
A 1 119 LEU 119 144 144 LEU LEU A . n 
A 1 120 PRO 120 145 145 PRO PRO A . n 
A 1 121 TYR 121 146 146 TYR TYR A . n 
A 1 122 TRP 122 147 147 TRP TRP A . n 
A 1 123 TYR 123 148 148 TYR TYR A . n 
A 1 124 VAL 124 149 149 VAL VAL A . n 
A 1 125 PHE 125 150 150 PHE PHE A . n 
A 1 126 LEU 126 151 151 LEU LEU A . n 
A 1 127 LEU 127 152 152 LEU LEU A . n 
A 1 128 ASP 128 153 153 ASP ASP A . n 
A 1 129 LYS 129 154 154 LYS LYS A . n 
A 1 130 THR 130 155 155 THR THR A . n 
A 1 131 SER 131 156 156 SER SER A . n 
A 1 132 TRP 132 157 157 TRP TRP A . n 
A 1 133 ASN 133 158 158 ASN ASN A . n 
A 1 134 ASN 134 159 159 ASN ASN A . n 
A 1 135 HIS 135 160 160 HIS HIS A . n 
A 1 136 SER 136 161 161 SER SER A . n 
A 1 137 TYR 137 162 162 TYR TYR A . n 
A 1 138 LEU 138 163 163 LEU LEU A . n 
A 1 139 TYR 139 164 164 TYR TYR A . n 
A 1 140 GLY 140 165 165 GLY GLY A . n 
A 1 141 LEU 141 166 166 LEU LEU A . n 
A 1 142 LEU 142 167 167 LEU LEU A . n 
A 1 143 ALA 143 168 168 ALA ALA A . n 
A 1 144 PHE 144 169 169 PHE PHE A . n 
A 1 145 GLN 145 170 170 GLN GLN A . n 
A 1 146 LEU 146 171 171 LEU LEU A . n 
A 1 147 THR 147 172 172 THR THR A . n 
A 1 148 PHE 148 173 173 PHE PHE A . n 
A 1 149 MET 149 174 174 MET MET A . n 
A 1 150 ASP 150 175 175 ASP ASP A . n 
A 1 151 ALA 151 176 176 ALA ALA A . n 
A 1 152 ASN 152 177 177 ASN ASN A . n 
A 1 153 HIS 153 178 178 HIS HIS A . n 
A 1 154 TYR 154 179 179 TYR TYR A . n 
A 1 155 TRP 155 180 180 TRP TRP A . n 
A 1 156 SER 156 181 181 SER SER A . n 
A 1 157 VAL 157 182 182 VAL VAL A . n 
A 1 158 ASP 158 183 183 ASP ASP A . n 
A 1 159 GLY 159 184 184 GLY GLY A . n 
A 1 160 LEU 160 185 185 LEU LEU A . n 
A 1 161 LEU 161 186 186 LEU LEU A . n 
A 1 162 ASN 162 187 187 ASN ASN A . n 
A 1 163 ALA 163 188 188 ALA ALA A . n 
A 1 164 HIS 164 189 189 HIS HIS A . n 
A 1 165 ARG 165 190 190 ARG ARG A . n 
A 1 166 ARG 166 191 191 ARG ARG A . n 
A 1 167 ASN 167 192 192 ASN ASN A . n 
A 1 168 ALA 168 193 193 ALA ALA A . n 
A 1 169 HIS 169 194 194 HIS HIS A . n 
A 1 170 VAL 170 195 195 VAL VAL A . n 
A 1 171 PRO 171 196 196 PRO PRO A . n 
A 1 172 LEU 172 197 197 LEU LEU A . n 
A 1 173 TRP 173 198 198 TRP TRP A . n 
A 1 174 ASN 174 199 199 ASN ASN A . n 
A 1 175 TYR 175 200 200 TYR TYR A . n 
A 1 176 ALA 176 201 201 ALA ALA A . n 
A 1 177 VAL 177 202 202 VAL VAL A . n 
A 1 178 LEU 178 203 203 LEU LEU A . n 
A 1 179 ARG 179 204 204 ARG ARG A . n 
A 1 180 GLY 180 205 205 GLY GLY A . n 
A 1 181 GLN 181 206 206 GLN GLN A . n 
A 1 182 ILE 182 207 207 ILE ILE A . n 
A 1 183 PHE 183 208 208 PHE PHE A . n 
A 1 184 ILE 184 209 209 ILE ILE A . n 
A 1 185 VAL 185 210 210 VAL VAL A . n 
A 1 186 TYR 186 211 211 TYR TYR A . n 
A 1 187 PHE 187 212 212 PHE PHE A . n 
A 1 188 ILE 188 213 213 ILE ILE A . n 
A 1 189 ALA 189 214 214 ALA ALA A . n 
A 1 190 GLY 190 215 215 GLY GLY A . n 
A 1 191 VAL 191 216 216 VAL VAL A . n 
A 1 192 LYS 192 217 217 LYS LYS A . n 
A 1 193 LYS 193 218 218 LYS LYS A . n 
A 1 194 LEU 194 219 219 LEU LEU A . n 
A 1 195 ASP 195 220 220 ASP ASP A . n 
A 1 196 ALA 196 221 221 ALA ALA A . n 
A 1 197 ASP 197 222 222 ASP ASP A . n 
A 1 198 TRP 198 223 223 TRP TRP A . n 
A 1 199 VAL 199 224 224 VAL VAL A . n 
A 1 200 GLU 200 225 225 GLU GLU A . n 
A 1 201 GLY 201 226 226 GLY GLY A . n 
A 1 202 TYR 202 227 227 TYR TYR A . n 
A 1 203 SER 203 228 228 SER SER A . n 
A 1 204 MET 204 229 229 MET MET A . n 
A 1 205 GLU 205 230 230 GLU GLU A . n 
A 1 206 TYR 206 231 231 TYR TYR A . n 
A 1 207 LEU 207 232 232 LEU LEU A . n 
A 1 208 SER 208 233 233 SER SER A . n 
A 1 209 ARG 209 234 234 ARG ARG A . n 
A 1 210 HIS 210 235 235 HIS HIS A . n 
A 1 211 TRP 211 236 236 TRP TRP A . n 
A 1 212 LEU 212 237 237 LEU LEU A . n 
A 1 213 PHE 213 238 238 PHE PHE A . n 
A 1 214 SER 214 239 239 SER SER A . n 
A 1 215 PRO 215 240 240 PRO PRO A . n 
A 1 216 PHE 216 241 241 PHE PHE A . n 
A 1 217 LYS 217 242 242 LYS LYS A . n 
A 1 218 LEU 218 243 243 LEU LEU A . n 
A 1 219 LEU 219 244 244 LEU LEU A . n 
A 1 220 LEU 220 245 245 LEU LEU A . n 
A 1 221 SER 221 246 246 SER SER A . n 
A 1 222 GLU 222 247 247 GLU GLU A . n 
A 1 223 GLU 223 248 248 GLU GLU A . n 
A 1 224 LEU 224 249 249 LEU LEU A . n 
A 1 225 THR 225 250 250 THR THR A . n 
A 1 226 SER 226 251 251 SER SER A . n 
A 1 227 LEU 227 252 252 LEU LEU A . n 
A 1 228 LEU 228 253 253 LEU LEU A . n 
A 1 229 VAL 229 254 254 VAL VAL A . n 
A 1 230 VAL 230 255 255 VAL VAL A . n 
A 1 231 HIS 231 256 256 HIS HIS A . n 
A 1 232 TRP 232 257 257 TRP TRP A . n 
A 1 233 GLY 233 258 258 GLY GLY A . n 
A 1 234 GLY 234 259 259 GLY GLY A . n 
A 1 235 LEU 235 260 260 LEU LEU A . n 
A 1 236 LEU 236 261 261 LEU LEU A . n 
A 1 237 LEU 237 262 262 LEU LEU A . n 
A 1 238 ASP 238 263 263 ASP ASP A . n 
A 1 239 LEU 239 264 264 LEU LEU A . n 
A 1 240 SER 240 265 265 SER SER A . n 
A 1 241 ALA 241 266 266 ALA ALA A . n 
A 1 242 GLY 242 267 267 GLY GLY A . n 
A 1 243 PHE 243 268 268 PHE PHE A . n 
A 1 244 LEU 244 269 269 LEU LEU A . n 
A 1 245 LEU 245 270 270 LEU LEU A . n 
A 1 246 PHE 246 271 271 PHE PHE A . n 
A 1 247 PHE 247 272 272 PHE PHE A . n 
A 1 248 ASP 248 273 273 ASP ASP A . n 
A 1 249 VAL 249 274 274 VAL VAL A . n 
A 1 250 SER 250 275 275 SER SER A . n 
A 1 251 ARG 251 276 276 ARG ARG A . n 
A 1 252 SER 252 277 277 SER SER A . n 
A 1 253 ILE 253 278 278 ILE ILE A . n 
A 1 254 GLY 254 279 279 GLY GLY A . n 
A 1 255 LEU 255 280 280 LEU LEU A . n 
A 1 256 PHE 256 281 281 PHE PHE A . n 
A 1 257 PHE 257 282 282 PHE PHE A . n 
A 1 258 VAL 258 283 283 VAL VAL A . n 
A 1 259 SER 259 284 284 SER SER A . n 
A 1 260 TYR 260 285 285 TYR TYR A . n 
A 1 261 PHE 261 286 286 PHE PHE A . n 
A 1 262 HIS 262 287 287 HIS HIS A . n 
A 1 263 CYS 263 288 288 CYS CYS A . n 
A 1 264 MET 264 289 289 MET MET A . n 
A 1 265 ASN 265 290 290 ASN ASN A . n 
A 1 266 SER 266 291 291 SER SER A . n 
A 1 267 GLN 267 292 292 GLN GLN A . n 
A 1 268 LEU 268 293 293 LEU LEU A . n 
A 1 269 PHE 269 294 294 PHE PHE A . n 
A 1 270 SER 270 295 295 SER SER A . n 
A 1 271 ILE 271 296 296 ILE ILE A . n 
A 1 272 GLY 272 297 297 GLY GLY A . n 
A 1 273 MET 273 298 298 MET MET A . n 
A 1 274 PHE 274 299 299 PHE PHE A . n 
A 1 275 SER 275 300 300 SER SER A . n 
A 1 276 TYR 276 301 301 TYR TYR A . n 
A 1 277 VAL 277 302 302 VAL VAL A . n 
A 1 278 MET 278 303 303 MET MET A . n 
A 1 279 LEU 279 304 304 LEU LEU A . n 
A 1 280 ALA 280 305 305 ALA ALA A . n 
A 1 281 SER 281 306 306 SER SER A . n 
A 1 282 SER 282 307 307 SER SER A . n 
A 1 283 PRO 283 308 308 PRO PRO A . n 
A 1 284 LEU 284 309 309 LEU LEU A . n 
A 1 285 PHE 285 310 310 PHE PHE A . n 
A 1 286 CYS 286 311 311 CYS CYS A . n 
A 1 287 SER 287 312 312 SER SER A . n 
A 1 288 PRO 288 313 313 PRO PRO A . n 
A 1 289 GLU 289 314 314 GLU GLU A . n 
A 1 290 TRP 290 315 315 TRP TRP A . n 
A 1 291 PRO 291 316 316 PRO PRO A . n 
A 1 292 ARG 292 317 317 ARG ARG A . n 
A 1 293 LYS 293 318 318 LYS LYS A . n 
A 1 294 LEU 294 319 319 LEU LEU A . n 
A 1 295 VAL 295 320 320 VAL VAL A . n 
A 1 296 SER 296 321 321 SER SER A . n 
A 1 297 TYR 297 322 322 TYR TYR A . n 
A 1 298 CYS 298 323 323 CYS CYS A . n 
A 1 299 PRO 299 324 324 PRO PRO A . n 
A 1 300 ARG 300 325 325 ARG ARG A . n 
A 1 301 ARG 301 326 326 ARG ARG A . n 
A 1 302 LEU 302 327 327 LEU LEU A . n 
A 1 303 GLN 303 328 328 GLN GLN A . n 
A 1 304 GLN 304 329 329 GLN GLN A . n 
A 1 305 LEU 305 330 330 LEU LEU A . n 
A 1 306 LEU 306 331 331 LEU LEU A . n 
A 1 307 PRO 307 332 332 PRO PRO A . n 
A 1 308 LEU 308 333 333 LEU LEU A . n 
A 1 309 LYS 309 334 334 LYS LYS A . n 
A 1 310 ALA 310 335 335 ALA ALA A . n 
A 1 311 ALA 311 336 336 ALA ALA A . n 
A 1 312 PRO 312 337 337 PRO PRO A . n 
A 1 313 GLN 313 338 338 GLN GLN A . n 
A 1 314 PRO 314 339 339 PRO PRO A . n 
A 1 315 SER 315 340 340 SER SER A . n 
A 1 316 VAL 316 341 341 VAL VAL A . n 
A 1 317 SER 317 342 342 SER SER A . n 
A 1 318 CYS 318 343 343 CYS CYS A . n 
A 1 319 VAL 319 344 344 VAL VAL A . n 
A 1 320 TYR 320 345 345 TYR TYR A . n 
A 1 321 LYS 321 346 346 LYS LYS A . n 
A 1 322 ARG 322 347 347 ARG ARG A . n 
A 1 323 SER 323 348 ?   ?   ?   A . n 
A 1 324 ARG 324 349 ?   ?   ?   A . n 
A 1 325 GLY 325 350 ?   ?   ?   A . n 
A 1 326 LYS 326 351 ?   ?   ?   A . n 
A 1 327 SER 327 352 ?   ?   ?   A . n 
A 1 328 GLY 328 353 353 GLY GLY A . n 
A 1 329 GLN 329 354 354 GLN GLN A . n 
A 1 330 LYS 330 355 355 LYS LYS A . n 
A 1 331 PRO 331 356 356 PRO PRO A . n 
A 1 332 GLY 332 357 357 GLY GLY A . n 
A 1 333 LEU 333 358 358 LEU LEU A . n 
A 1 334 ARG 334 359 359 ARG ARG A . n 
A 1 335 HIS 335 360 360 HIS HIS A . n 
A 1 336 GLN 336 361 361 GLN GLN A . n 
A 1 337 LEU 337 362 362 LEU LEU A . n 
A 1 338 GLY 338 363 363 GLY GLY A . n 
A 1 339 ALA 339 364 364 ALA ALA A . n 
A 1 340 ALA 340 365 365 ALA ALA A . n 
A 1 341 PHE 341 366 366 PHE PHE A . n 
A 1 342 THR 342 367 367 THR THR A . n 
A 1 343 LEU 343 368 368 LEU LEU A . n 
A 1 344 LEU 344 369 369 LEU LEU A . n 
A 1 345 TYR 345 370 370 TYR TYR A . n 
A 1 346 LEU 346 371 371 LEU LEU A . n 
A 1 347 LEU 347 372 372 LEU LEU A . n 
A 1 348 GLU 348 373 373 GLU GLU A . n 
A 1 349 GLN 349 374 374 GLN GLN A . n 
A 1 350 LEU 350 375 375 LEU LEU A . n 
A 1 351 PHE 351 376 376 PHE PHE A . n 
A 1 352 LEU 352 377 377 LEU LEU A . n 
A 1 353 PRO 353 378 378 PRO PRO A . n 
A 1 354 TYR 354 379 379 TYR TYR A . n 
A 1 355 SER 355 380 380 SER SER A . n 
A 1 356 HIS 356 381 381 HIS HIS A . n 
A 1 357 PHE 357 382 382 PHE PHE A . n 
A 1 358 LEU 358 383 383 LEU LEU A . n 
A 1 359 THR 359 384 384 THR THR A . n 
A 1 360 GLN 360 385 385 GLN GLN A . n 
A 1 361 GLY 361 386 386 GLY GLY A . n 
A 1 362 TYR 362 387 387 TYR TYR A . n 
A 1 363 ASN 363 388 388 ASN ASN A . n 
A 1 364 ASN 364 389 389 ASN ASN A . n 
A 1 365 TRP 365 390 390 TRP TRP A . n 
A 1 366 THR 366 391 391 THR THR A . n 
A 1 367 ASN 367 392 392 ASN ASN A . n 
A 1 368 GLY 368 393 393 GLY GLY A . n 
A 1 369 LEU 369 394 394 LEU LEU A . n 
A 1 370 TYR 370 395 395 TYR TYR A . n 
A 1 371 GLY 371 396 396 GLY GLY A . n 
A 1 372 TYR 372 397 397 TYR TYR A . n 
A 1 373 SER 373 398 398 SER SER A . n 
A 1 374 TRP 374 399 399 TRP TRP A . n 
A 1 375 ASP 375 400 400 ASP ASP A . n 
A 1 376 MET 376 401 401 MET MET A . n 
A 1 377 MET 377 402 402 MET MET A . n 
A 1 378 VAL 378 403 403 VAL VAL A . n 
A 1 379 HIS 379 404 404 HIS HIS A . n 
A 1 380 SER 380 405 405 SER SER A . n 
A 1 381 ARG 381 406 406 ARG ARG A . n 
A 1 382 SER 382 407 407 SER SER A . n 
A 1 383 HIS 383 408 408 HIS HIS A . n 
A 1 384 GLN 384 409 409 GLN GLN A . n 
A 1 385 HIS 385 410 410 HIS HIS A . n 
A 1 386 VAL 386 411 411 VAL VAL A . n 
A 1 387 LYS 387 412 412 LYS LYS A . n 
A 1 388 ILE 388 413 413 ILE ILE A . n 
A 1 389 THR 389 414 414 THR THR A . n 
A 1 390 TYR 390 415 415 TYR TYR A . n 
A 1 391 ARG 391 416 416 ARG ARG A . n 
A 1 392 ASP 392 417 417 ASP ASP A . n 
A 1 393 GLY 393 418 418 GLY GLY A . n 
A 1 394 ARG 394 419 419 ARG ARG A . n 
A 1 395 THR 395 420 420 THR THR A . n 
A 1 396 GLY 396 421 421 GLY GLY A . n 
A 1 397 GLU 397 422 422 GLU GLU A . n 
A 1 398 LEU 398 423 423 LEU LEU A . n 
A 1 399 GLY 399 424 424 GLY GLY A . n 
A 1 400 TYR 400 425 425 TYR TYR A . n 
A 1 401 LEU 401 426 426 LEU LEU A . n 
A 1 402 ASN 402 427 427 ASN ASN A . n 
A 1 403 PRO 403 428 428 PRO PRO A . n 
A 1 404 GLY 404 429 429 GLY GLY A . n 
A 1 405 VAL 405 430 430 VAL VAL A . n 
A 1 406 PHE 406 431 431 PHE PHE A . n 
A 1 407 THR 407 432 432 THR THR A . n 
A 1 408 GLN 408 433 433 GLN GLN A . n 
A 1 409 SER 409 434 434 SER SER A . n 
A 1 410 ARG 410 435 435 ARG ARG A . n 
A 1 411 ARG 411 436 436 ARG ARG A . n 
A 1 412 TRP 412 437 437 TRP TRP A . n 
A 1 413 LYS 413 438 438 LYS LYS A . n 
A 1 414 ASP 414 439 439 ASP ASP A . n 
A 1 415 HIS 415 440 440 HIS HIS A . n 
A 1 416 ALA 416 441 441 ALA ALA A . n 
A 1 417 ASP 417 442 442 ASP ASP A . n 
A 1 418 MET 418 443 443 MET MET A . n 
A 1 419 LEU 419 444 444 LEU LEU A . n 
A 1 420 LYS 420 445 445 LYS LYS A . n 
A 1 421 GLN 421 446 446 GLN GLN A . n 
A 1 422 TYR 422 447 447 TYR TYR A . n 
A 1 423 ALA 423 448 448 ALA ALA A . n 
A 1 424 THR 424 449 449 THR THR A . n 
A 1 425 CYS 425 450 450 CYS CYS A . n 
A 1 426 LEU 426 451 451 LEU LEU A . n 
A 1 427 SER 427 452 452 SER SER A . n 
A 1 428 ARG 428 453 453 ARG ARG A . n 
A 1 429 LEU 429 454 454 LEU LEU A . n 
A 1 430 LEU 430 455 455 LEU LEU A . n 
A 1 431 PRO 431 456 456 PRO PRO A . n 
A 1 432 LYS 432 457 457 LYS LYS A . n 
A 1 433 TYR 433 458 458 TYR TYR A . n 
A 1 434 ASN 434 459 459 ASN ASN A . n 
A 1 435 VAL 435 460 460 VAL VAL A . n 
A 1 436 THR 436 461 461 THR THR A . n 
A 1 437 GLU 437 462 462 GLU GLU A . n 
A 1 438 PRO 438 463 463 PRO PRO A . n 
A 1 439 GLN 439 464 464 GLN GLN A . n 
A 1 440 ILE 440 465 465 ILE ILE A . n 
A 1 441 TYR 441 466 466 TYR TYR A . n 
A 1 442 PHE 442 467 467 PHE PHE A . n 
A 1 443 ASP 443 468 468 ASP ASP A . n 
A 1 444 ILE 444 469 469 ILE ILE A . n 
A 1 445 TRP 445 470 470 TRP TRP A . n 
A 1 446 VAL 446 471 471 VAL VAL A . n 
A 1 447 SER 447 472 472 SER SER A . n 
A 1 448 ILE 448 473 473 ILE ILE A . n 
A 1 449 ASN 449 474 474 ASN ASN A . n 
A 1 450 ASP 450 475 475 ASP ASP A . n 
A 1 451 ARG 451 476 476 ARG ARG A . n 
A 1 452 PHE 452 477 477 PHE PHE A . n 
A 1 453 GLN 453 478 478 GLN GLN A . n 
A 1 454 GLN 454 479 479 GLN GLN A . n 
A 1 455 ARG 455 480 480 ARG ARG A . n 
A 1 456 ILE 456 481 481 ILE ILE A . n 
A 1 457 PHE 457 482 482 PHE PHE A . n 
A 1 458 ASP 458 483 483 ASP ASP A . n 
A 1 459 PRO 459 484 484 PRO PRO A . n 
A 1 460 ARG 460 485 485 ARG ARG A . n 
A 1 461 VAL 461 486 486 VAL VAL A . n 
A 1 462 ASP 462 487 487 ASP ASP A . n 
A 1 463 ILE 463 488 488 ILE ILE A . n 
A 1 464 VAL 464 489 489 VAL VAL A . n 
A 1 465 GLN 465 490 490 GLN GLN A . n 
A 1 466 ALA 466 491 491 ALA ALA A . n 
A 1 467 ALA 467 492 492 ALA ALA A . n 
A 1 468 TRP 468 493 493 TRP TRP A . n 
A 1 469 SER 469 494 494 SER SER A . n 
A 1 470 PRO 470 495 495 PRO PRO A . n 
A 1 471 PHE 471 496 496 PHE PHE A . n 
A 1 472 GLN 472 497 497 GLN GLN A . n 
A 1 473 ARG 473 498 498 ARG ARG A . n 
A 1 474 THR 474 499 499 THR THR A . n 
A 1 475 SER 475 500 500 SER SER A . n 
A 1 476 TRP 476 501 501 TRP TRP A . n 
A 1 477 VAL 477 502 502 VAL VAL A . n 
A 1 478 GLN 478 503 503 GLN GLN A . n 
A 1 479 PRO 479 504 504 PRO PRO A . n 
A 1 480 LEU 480 505 505 LEU LEU A . n 
A 1 481 LEU 481 506 506 LEU LEU A . n 
A 1 482 MET 482 507 507 MET MET A . n 
A 1 483 ASP 483 508 508 ASP ASP A . n 
A 1 484 LEU 484 509 509 LEU LEU A . n 
A 1 485 SER 485 510 510 SER SER A . n 
A 1 486 PRO 486 511 511 PRO PRO A . n 
A 1 487 TRP 487 512 512 TRP TRP A . n 
A 1 488 ARG 488 513 513 ARG ARG A . n 
A 1 489 ALA 489 514 514 ALA ALA A . n 
A 1 490 LYS 490 515 515 LYS LYS A . n 
A 1 491 LEU 491 516 516 LEU LEU A . n 
A 1 492 GLN 492 517 517 GLN GLN A . n 
A 1 493 GLU 493 518 518 GLU GLU A . n 
A 1 494 ILE 494 519 519 ILE ILE A . n 
A 1 495 LYS 495 520 520 LYS LYS A . n 
A 1 496 SER 496 521 521 SER SER A . n 
A 1 497 SER 497 522 522 SER SER A . n 
A 1 498 LEU 498 523 523 LEU LEU A . n 
A 1 499 ASP 499 524 524 ASP ASP A . n 
A 1 500 ASN 500 525 525 ASN ASN A . n 
A 1 501 HIS 501 526 526 HIS HIS A . n 
A 1 502 THR 502 527 527 THR THR A . n 
A 1 503 GLU 503 528 528 GLU GLU A . n 
A 1 504 VAL 504 529 529 VAL VAL A . n 
A 1 505 VAL 505 530 530 VAL VAL A . n 
A 1 506 PHE 506 531 531 PHE PHE A . n 
A 1 507 ILE 507 532 532 ILE ILE A . n 
A 1 508 ALA 508 533 533 ALA ALA A . n 
A 1 509 ASP 509 534 534 ASP ASP A . n 
A 1 510 PHE 510 535 535 PHE PHE A . n 
A 1 511 PRO 511 536 536 PRO PRO A . n 
A 1 512 GLY 512 537 537 GLY GLY A . n 
A 1 513 LEU 513 538 538 LEU LEU A . n 
A 1 514 HIS 514 539 539 HIS HIS A . n 
A 1 515 LEU 515 540 540 LEU LEU A . n 
A 1 516 GLU 516 541 541 GLU GLU A . n 
A 1 517 ASN 517 542 542 ASN ASN A . n 
A 1 518 PHE 518 543 543 PHE PHE A . n 
A 1 519 VAL 519 544 544 VAL VAL A . n 
A 1 520 SER 520 545 545 SER SER A . n 
A 1 521 GLU 521 546 546 GLU GLU A . n 
A 1 522 ASP 522 547 547 ASP ASP A . n 
A 1 523 LEU 523 548 548 LEU LEU A . n 
A 1 524 GLY 524 549 549 GLY GLY A . n 
A 1 525 ASN 525 550 550 ASN ASN A . n 
A 1 526 THR 526 551 551 THR THR A . n 
A 1 527 SER 527 552 552 SER SER A . n 
A 1 528 ILE 528 553 553 ILE ILE A . n 
A 1 529 GLN 529 554 554 GLN GLN A . n 
A 1 530 LEU 530 555 555 LEU LEU A . n 
A 1 531 LEU 531 556 556 LEU LEU A . n 
A 1 532 GLN 532 557 557 GLN GLN A . n 
A 1 533 GLY 533 558 558 GLY GLY A . n 
A 1 534 GLU 534 559 559 GLU GLU A . n 
A 1 535 VAL 535 560 560 VAL VAL A . n 
A 1 536 THR 536 561 561 THR THR A . n 
A 1 537 VAL 537 562 562 VAL VAL A . n 
A 1 538 GLU 538 563 563 GLU GLU A . n 
A 1 539 LEU 539 564 564 LEU LEU A . n 
A 1 540 VAL 540 565 565 VAL VAL A . n 
A 1 541 ALA 541 566 566 ALA ALA A . n 
A 1 542 GLU 542 567 567 GLU GLU A . n 
A 1 543 GLN 543 568 568 GLN GLN A . n 
A 1 544 LYS 544 569 569 LYS LYS A . n 
A 1 545 ASN 545 570 570 ASN ASN A . n 
A 1 546 GLN 546 571 571 GLN GLN A . n 
A 1 547 THR 547 572 572 THR THR A . n 
A 1 548 LEU 548 573 573 LEU LEU A . n 
A 1 549 ARG 549 574 574 ARG ARG A . n 
A 1 550 GLU 550 575 575 GLU GLU A . n 
A 1 551 GLY 551 576 576 GLY GLY A . n 
A 1 552 GLU 552 577 577 GLU GLU A . n 
A 1 553 LYS 553 578 578 LYS LYS A . n 
A 1 554 MET 554 579 579 MET MET A . n 
A 1 555 GLN 555 580 580 GLN GLN A . n 
A 1 556 LEU 556 581 581 LEU LEU A . n 
A 1 557 PRO 557 582 582 PRO PRO A . n 
A 1 558 ALA 558 583 583 ALA ALA A . n 
A 1 559 GLY 559 584 584 GLY GLY A . n 
A 1 560 GLU 560 585 585 GLU GLU A . n 
A 1 561 TYR 561 586 586 TYR TYR A . n 
A 1 562 HIS 562 587 587 HIS HIS A . n 
A 1 563 LYS 563 588 588 LYS LYS A . n 
A 1 564 VAL 564 589 589 VAL VAL A . n 
A 1 565 TYR 565 590 590 TYR TYR A . n 
A 1 566 THR 566 591 591 THR THR A . n 
A 1 567 THR 567 592 592 THR THR A . n 
A 1 568 SER 568 593 593 SER SER A . n 
A 1 569 PRO 569 594 594 PRO PRO A . n 
A 1 570 SER 570 595 595 SER SER A . n 
A 1 571 PRO 571 596 596 PRO PRO A . n 
A 1 572 SER 572 597 597 SER SER A . n 
A 1 573 CYS 573 598 598 CYS CYS A . n 
A 1 574 TYR 574 599 599 TYR TYR A . n 
A 1 575 MET 575 600 600 MET MET A . n 
A 1 576 TYR 576 601 601 TYR TYR A . n 
A 1 577 VAL 577 602 602 VAL VAL A . n 
A 1 578 TYR 578 603 603 TYR TYR A . n 
A 1 579 VAL 579 604 604 VAL VAL A . n 
A 1 580 ASN 580 605 605 ASN ASN A . n 
A 1 581 THR 581 606 606 THR THR A . n 
A 1 582 THR 582 607 607 THR THR A . n 
A 1 583 GLU 583 608 608 GLU GLU A . n 
A 1 584 LEU 584 609 609 LEU LEU A . n 
A 1 585 ALA 585 610 610 ALA ALA A . n 
A 1 586 LEU 586 611 611 LEU LEU A . n 
A 1 587 GLU 587 612 612 GLU GLU A . n 
A 1 588 GLN 588 613 613 GLN GLN A . n 
A 1 589 ASP 589 614 614 ASP ASP A . n 
A 1 590 LEU 590 615 615 LEU LEU A . n 
A 1 591 ALA 591 616 616 ALA ALA A . n 
A 1 592 TYR 592 617 617 TYR TYR A . n 
A 1 593 LEU 593 618 618 LEU LEU A . n 
A 1 594 GLN 594 619 619 GLN GLN A . n 
A 1 595 GLU 595 620 620 GLU GLU A . n 
A 1 596 LEU 596 621 621 LEU LEU A . n 
A 1 597 LYS 597 622 622 LYS LYS A . n 
A 1 598 GLU 598 623 623 GLU GLU A . n 
A 1 599 LYS 599 624 624 LYS LYS A . n 
A 1 600 VAL 600 625 625 VAL VAL A . n 
A 1 601 GLU 601 626 626 GLU GLU A . n 
A 1 602 ASN 602 627 627 ASN ASN A . n 
A 1 603 GLY 603 628 628 GLY GLY A . n 
A 1 604 SER 604 629 629 SER SER A . n 
A 1 605 GLU 605 630 630 GLU GLU A . n 
A 1 606 THR 606 631 631 THR THR A . n 
A 1 607 GLY 607 632 632 GLY GLY A . n 
A 1 608 PRO 608 633 633 PRO PRO A . n 
A 1 609 LEU 609 634 634 LEU LEU A . n 
A 1 610 PRO 610 635 635 PRO PRO A . n 
A 1 611 PRO 611 636 636 PRO PRO A . n 
A 1 612 GLU 612 637 637 GLU GLU A . n 
A 1 613 LEU 613 638 638 LEU LEU A . n 
A 1 614 GLN 614 639 639 GLN GLN A . n 
A 1 615 PRO 615 640 640 PRO PRO A . n 
A 1 616 LEU 616 641 641 LEU LEU A . n 
A 1 617 LEU 617 642 642 LEU LEU A . n 
A 1 618 GLU 618 643 643 GLU GLU A . n 
A 1 619 GLY 619 644 644 GLY GLY A . n 
A 1 620 GLU 620 645 645 GLU GLU A . n 
A 1 621 VAL 621 646 646 VAL VAL A . n 
A 1 622 LYS 622 647 647 LYS LYS A . n 
A 1 623 GLY 623 648 648 GLY GLY A . n 
A 1 624 GLY 624 649 649 GLY GLY A . n 
A 1 625 PRO 625 650 650 PRO PRO A . n 
A 1 626 GLU 626 651 651 GLU GLU A . n 
A 1 627 PRO 627 652 652 PRO PRO A . n 
A 1 628 THR 628 653 653 THR THR A . n 
A 1 629 PRO 629 654 654 PRO PRO A . n 
A 1 630 LEU 630 655 655 LEU LEU A . n 
A 1 631 VAL 631 656 656 VAL VAL A . n 
A 1 632 GLN 632 657 657 GLN GLN A . n 
A 1 633 THR 633 658 658 THR THR A . n 
A 1 634 PHE 634 659 659 PHE PHE A . n 
A 1 635 LEU 635 660 660 LEU LEU A . n 
A 1 636 ARG 636 661 661 ARG ARG A . n 
A 1 637 ARG 637 662 662 ARG ARG A . n 
A 1 638 GLN 638 663 663 GLN GLN A . n 
A 1 639 GLN 639 664 664 GLN GLN A . n 
A 1 640 ARG 640 665 665 ARG ARG A . n 
A 1 641 LEU 641 666 666 LEU LEU A . n 
A 1 642 GLN 642 667 667 GLN GLN A . n 
A 1 643 GLU 643 668 668 GLU GLU A . n 
A 1 644 ILE 644 669 669 ILE ILE A . n 
A 1 645 GLU 645 670 670 GLU GLU A . n 
A 1 646 ARG 646 671 671 ARG ARG A . n 
A 1 647 ARG 647 672 672 ARG ARG A . n 
A 1 648 ARG 648 673 673 ARG ARG A . n 
A 1 649 ASN 649 674 674 ASN ASN A . n 
A 1 650 THR 650 675 675 THR THR A . n 
A 1 651 PRO 651 676 676 PRO PRO A . n 
A 1 652 PHE 652 677 677 PHE PHE A . n 
A 1 653 HIS 653 678 678 HIS HIS A . n 
A 1 654 GLU 654 679 679 GLU GLU A . n 
A 1 655 ARG 655 680 680 ARG ARG A . n 
A 1 656 PHE 656 681 681 PHE PHE A . n 
A 1 657 PHE 657 682 682 PHE PHE A . n 
A 1 658 ARG 658 683 683 ARG ARG A . n 
A 1 659 PHE 659 684 684 PHE PHE A . n 
A 1 660 LEU 660 685 685 LEU LEU A . n 
A 1 661 LEU 661 686 686 LEU LEU A . n 
A 1 662 ARG 662 687 687 ARG ARG A . n 
A 1 663 LYS 663 688 688 LYS LYS A . n 
A 1 664 LEU 664 689 689 LEU LEU A . n 
A 1 665 TYR 665 690 690 TYR TYR A . n 
A 1 666 VAL 666 691 691 VAL VAL A . n 
A 1 667 PHE 667 692 692 PHE PHE A . n 
A 1 668 ARG 668 693 693 ARG ARG A . n 
A 1 669 ARG 669 694 694 ARG ARG A . n 
A 1 670 SER 670 695 695 SER SER A . n 
A 1 671 PHE 671 696 696 PHE PHE A . n 
A 1 672 LEU 672 697 697 LEU LEU A . n 
A 1 673 MET 673 698 698 MET MET A . n 
A 1 674 THR 674 699 699 THR THR A . n 
A 1 675 CYS 675 700 700 CYS CYS A . n 
A 1 676 ILE 676 701 701 ILE ILE A . n 
A 1 677 SER 677 702 702 SER SER A . n 
A 1 678 LEU 678 703 703 LEU LEU A . n 
A 1 679 ARG 679 704 704 ARG ARG A . n 
A 1 680 ASN 680 705 705 ASN ASN A . n 
A 1 681 LEU 681 706 706 LEU LEU A . n 
A 1 682 ILE 682 707 707 ILE ILE A . n 
A 1 683 LEU 683 708 708 LEU LEU A . n 
A 1 684 GLY 684 709 709 GLY GLY A . n 
A 1 685 ARG 685 710 710 ARG ARG A . n 
A 1 686 PRO 686 711 711 PRO PRO A . n 
A 1 687 SER 687 712 712 SER SER A . n 
A 1 688 LEU 688 713 713 LEU LEU A . n 
A 1 689 GLU 689 714 714 GLU GLU A . n 
A 1 690 GLN 690 715 715 GLN GLN A . n 
A 1 691 LEU 691 716 716 LEU LEU A . n 
A 1 692 ALA 692 717 717 ALA ALA A . n 
A 1 693 GLN 693 718 718 GLN GLN A . n 
A 1 694 GLU 694 719 719 GLU GLU A . n 
A 1 695 VAL 695 720 720 VAL VAL A . n 
A 1 696 THR 696 721 721 THR THR A . n 
A 1 697 TYR 697 722 722 TYR TYR A . n 
A 1 698 ALA 698 723 723 ALA ALA A . n 
A 1 699 ASN 699 724 724 ASN ASN A . n 
A 1 700 LEU 700 725 725 LEU LEU A . n 
A 1 701 ARG 701 726 726 ARG ARG A . n 
A 1 702 PRO 702 727 727 PRO PRO A . n 
A 1 703 PHE 703 728 728 PHE PHE A . n 
A 1 704 GLU 704 729 ?   ?   ?   A . n 
A 1 705 ALA 705 730 ?   ?   ?   A . n 
A 1 706 VAL 706 731 ?   ?   ?   A . n 
A 1 707 GLY 707 732 ?   ?   ?   A . n 
A 1 708 GLU 708 733 ?   ?   ?   A . n 
A 1 709 LEU 709 734 ?   ?   ?   A . n 
A 1 710 ASN 710 735 ?   ?   ?   A . n 
A 1 711 PRO 711 736 ?   ?   ?   A . n 
A 1 712 SER 712 737 ?   ?   ?   A . n 
A 1 713 ASN 713 738 ?   ?   ?   A . n 
A 1 714 THR 714 739 ?   ?   ?   A . n 
A 1 715 ASP 715 740 ?   ?   ?   A . n 
A 1 716 SER 716 741 ?   ?   ?   A . n 
A 1 717 SER 717 742 ?   ?   ?   A . n 
A 1 718 HIS 718 743 ?   ?   ?   A . n 
A 1 719 SER 719 744 ?   ?   ?   A . n 
A 1 720 ASN 720 745 ?   ?   ?   A . n 
A 1 721 PRO 721 746 ?   ?   ?   A . n 
A 1 722 PRO 722 747 ?   ?   ?   A . n 
A 1 723 GLU 723 748 ?   ?   ?   A . n 
A 1 724 SER 724 749 ?   ?   ?   A . n 
A 1 725 ASN 725 750 ?   ?   ?   A . n 
A 1 726 PRO 726 751 ?   ?   ?   A . n 
A 1 727 ASP 727 752 ?   ?   ?   A . n 
A 1 728 PRO 728 753 ?   ?   ?   A . n 
A 1 729 VAL 729 754 ?   ?   ?   A . n 
A 1 730 HIS 730 755 ?   ?   ?   A . n 
A 1 731 SER 731 756 ?   ?   ?   A . n 
A 1 732 GLU 732 757 ?   ?   ?   A . n 
A 1 733 PHE 733 758 ?   ?   ?   A . n 
B 2 1   GLU 1   24  24  GLU GLU P . n 
B 2 2   GLU 2   25  25  GLU GLU P . n 
B 2 3   THR 3   26  26  THR THR P . n 
B 2 4   ASP 4   27  27  ASP ASP P . n 
B 2 5   GLN 5   28  28  GLN GLN P . n 
B 2 6   GLU 6   29  29  GLU GLU P . n 
B 2 7   VAL 7   30  30  VAL VAL P . n 
B 2 8   PHE 8   31  31  PHE PHE P . n 
B 2 9   LEU 9   32  32  LEU LEU P . n 
B 2 10  GLY 10  33  33  GLY GLY P . n 
B 2 11  PRO 11  34  34  PRO PRO P . n 
B 2 12  PRO 12  35  35  PRO PRO P . n 
B 2 13  GLU 13  36  36  GLU GLU P . n 
B 2 14  ALA 14  37  37  ALA ALA P . n 
B 2 15  GLN 15  38  38  GLN GLN P . n 
B 2 16  SER 16  39  39  SER SER P . n 
B 2 17  PHE 17  40  40  PHE PHE P . n 
B 2 18  LEU 18  41  41  LEU LEU P . n 
B 2 19  SER 19  42  42  SER SER P . n 
B 2 20  SER 20  43  43  SER SER P . n 
B 2 21  HIS 21  44  44  HIS HIS P . n 
B 2 22  THR 22  45  45  THR THR P . n 
B 2 23  ARG 23  46  ?   ?   ?   P . n 
B 2 24  ILE 24  47  ?   ?   ?   P . n 
B 2 25  PRO 25  48  ?   ?   ?   P . n 
B 2 26  ARG 26  49  ?   ?   ?   P . n 
B 2 27  ALA 27  50  ?   ?   ?   P . n 
B 2 28  ASN 28  51  ?   ?   ?   P . n 
B 2 29  HIS 29  52  ?   ?   ?   P . n 
B 2 30  TRP 30  53  ?   ?   ?   P . n 
B 2 31  ASP 31  54  ?   ?   ?   P . n 
B 2 32  LEU 32  55  ?   ?   ?   P . n 
B 2 33  GLU 33  56  ?   ?   ?   P . n 
B 2 34  LEU 34  57  ?   ?   ?   P . n 
B 2 35  LEU 35  58  ?   ?   ?   P . n 
B 2 36  THR 36  59  ?   ?   ?   P . n 
B 2 37  PRO 37  60  ?   ?   ?   P . n 
B 2 38  GLY 38  61  ?   ?   ?   P . n 
B 2 39  ASN 39  62  ?   ?   ?   P . n 
B 2 40  LEU 40  63  ?   ?   ?   P . n 
B 2 41  GLU 41  64  ?   ?   ?   P . n 
B 2 42  ARG 42  65  ?   ?   ?   P . n 
B 2 43  GLU 43  66  ?   ?   ?   P . n 
B 2 44  CYS 44  67  ?   ?   ?   P . n 
B 2 45  LEU 45  68  ?   ?   ?   P . n 
B 2 46  GLU 46  69  ?   ?   ?   P . n 
B 2 47  GLU 47  70  ?   ?   ?   P . n 
B 2 48  ARG 48  71  ?   ?   ?   P . n 
B 2 49  CYS 49  72  ?   ?   ?   P . n 
B 2 50  SER 50  73  ?   ?   ?   P . n 
B 2 51  TRP 51  74  ?   ?   ?   P . n 
B 2 52  GLU 52  75  ?   ?   ?   P . n 
B 2 53  GLU 53  76  ?   ?   ?   P . n 
B 2 54  ALA 54  77  ?   ?   ?   P . n 
B 2 55  ARG 55  78  ?   ?   ?   P . n 
B 2 56  GLU 56  79  ?   ?   ?   P . n 
B 2 57  TYR 57  80  ?   ?   ?   P . n 
B 2 58  PHE 58  81  ?   ?   ?   P . n 
B 2 59  GLU 59  82  ?   ?   ?   P . n 
B 2 60  ASP 60  83  ?   ?   ?   P . n 
B 2 61  ASN 61  84  ?   ?   ?   P . n 
B 2 62  THR 62  85  ?   ?   ?   P . n 
B 2 63  LEU 63  86  86  LEU LEU P . n 
B 2 64  THR 64  87  87  THR THR P . n 
B 2 65  GLU 65  88  88  GLU GLU P . n 
B 2 66  ARG 66  89  89  ARG ARG P . n 
B 2 67  PHE 67  90  90  PHE PHE P . n 
B 2 68  TRP 68  91  91  TRP TRP P . n 
B 2 69  GLU 69  92  92  GLU GLU P . n 
B 2 70  SER 70  93  93  SER SER P . n 
B 2 71  TYR 71  94  94  TYR TYR P . n 
B 2 72  ILE 72  95  95  ILE ILE P . n 
B 2 73  TYR 73  96  96  TYR TYR P . n 
B 2 74  ASN 74  97  97  ASN ASN P . n 
B 2 75  GLY 75  98  98  GLY GLY P . n 
B 2 76  LYS 76  99  ?   ?   ?   P . n 
B 2 77  GLY 77  100 ?   ?   ?   P . n 
B 2 78  GLY 78  101 ?   ?   ?   P . n 
B 2 79  ARG 79  102 ?   ?   ?   P . n 
B 2 80  GLY 80  103 ?   ?   ?   P . n 
B 2 81  ARG 81  104 ?   ?   ?   P . n 
B 2 82  VAL 82  105 ?   ?   ?   P . n 
B 2 83  ASP 83  106 ?   ?   ?   P . n 
B 2 84  VAL 84  107 ?   ?   ?   P . n 
B 2 85  ALA 85  108 ?   ?   ?   P . n 
B 2 86  SER 86  109 ?   ?   ?   P . n 
B 2 87  LEU 87  110 ?   ?   ?   P . n 
B 2 88  ALA 88  111 ?   ?   ?   P . n 
B 2 89  VAL 89  112 ?   ?   ?   P . n 
B 2 90  GLY 90  113 ?   ?   ?   P . n 
B 2 91  LEU 91  114 ?   ?   ?   P . n 
B 2 92  THR 92  115 ?   ?   ?   P . n 
B 2 93  GLY 93  116 ?   ?   ?   P . n 
B 2 94  GLY 94  117 ?   ?   ?   P . n 
B 2 95  ILE 95  118 ?   ?   ?   P . n 
B 2 96  LEU 96  119 ?   ?   ?   P . n 
B 2 97  LEU 97  120 ?   ?   ?   P . n 
B 2 98  ILE 98  121 ?   ?   ?   P . n 
B 2 99  VAL 99  122 ?   ?   ?   P . n 
B 2 100 LEU 100 123 ?   ?   ?   P . n 
B 2 101 ALA 101 124 ?   ?   ?   P . n 
B 2 102 GLY 102 125 ?   ?   ?   P . n 
B 2 103 LEU 103 126 ?   ?   ?   P . n 
B 2 104 GLY 104 127 ?   ?   ?   P . n 
B 2 105 ALA 105 128 ?   ?   ?   P . n 
B 2 106 PHE 106 129 ?   ?   ?   P . n 
B 2 107 TRP 107 130 ?   ?   ?   P . n 
B 2 108 TYR 108 131 ?   ?   ?   P . n 
B 2 109 LEU 109 132 ?   ?   ?   P . n 
B 2 110 ARG 110 133 ?   ?   ?   P . n 
B 2 111 TRP 111 134 ?   ?   ?   P . n 
B 2 112 ARG 112 135 ?   ?   ?   P . n 
B 2 113 GLN 113 136 ?   ?   ?   P . n 
B 2 114 HIS 114 137 ?   ?   ?   P . n 
B 2 115 ARG 115 138 ?   ?   ?   P . n 
B 2 116 GLY 116 139 ?   ?   ?   P . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
C 3 NAG 1 B NAG 1 B NAG 1 n 
C 3 NAG 2 B NAG 2 B NAG 2 n 
D 3 NAG 1 C NAG 1 C NAG 1 n 
D 3 NAG 2 C NAG 2 C NAG 2 n 
E 3 NAG 1 D NAG 1 D NAG 1 n 
E 3 NAG 2 D NAG 2 D NAG 2 n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 6PL   ? ? 6PL   ? ? 'SUBJECT OF INVESTIGATION' ? 
2 A1AVC ? ? A1AVC ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
F 4 A1AVC 1 801 801 A1AVC KH2 A . 
G 5 6PL   1 802 802 6PL   6PL A . 
H 5 6PL   1 803 803 6PL   6PL A . 
I 6 NAG   1 804 13  NAG   NAG A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 N 1 A 6PL 802 ? C26 ? G 6PL 1 C26 
2 1 N 1 A 6PL 802 ? C25 ? G 6PL 1 C25 
3 1 N 1 A 6PL 802 ? C24 ? G 6PL 1 C24 
4 1 N 1 A 6PL 802 ? C23 ? G 6PL 1 C23 
5 1 N 1 A 6PL 802 ? C47 ? G 6PL 1 C47 
6 1 N 1 A 6PL 802 ? C48 ? G 6PL 1 C48 
7 1 N 1 A 6PL 803 ? C47 ? H 6PL 1 C47 
8 1 N 1 A 6PL 803 ? C48 ? H 6PL 1 C48 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BVP 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BVP 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BVP 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9BVP 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004  ? 6406 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.627  ? 8684 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 10.624 ? 2501 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.039  ? 933  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.006  ? 1077 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9BVP 
_struct.title                        
'Vitamin K-dependent gamma-carboxylase with TMG2 propeptide and glutamate-rich region and with vitamin K hydroquinone' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BVP 
_struct_keywords.text            
;GGCX, VKGC, Vitamin K, VKCFD, Hemophilia B, Warfarin, Carboxylation, Blood Coagulaton, Calcium homeostasis, TMG, MEMBRANE PROTEIN, LYASE-SUBSTRATE complex
;
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN,LYASE/SUBSTRATE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 3 ? 
F N N 4 ? 
G N N 5 ? 
H N N 5 ? 
I N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP VKGC_HUMAN P38435 ? 1 
;SGPRQDSRIGKLLGFEWTDLSSWRRLVTLLNRPTDPASLAVFRFLFGFLMVLDIPQERGLSSLDRKYLDGLDVCRFPLLD
ALRPLPLDWMYLVYTIMFLGALGMMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGL
LNAHRRNAHVPLWNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKLLLSEELTSLLVVHWGGLLLDLS
AGFLLFFDVSRSIGLFFVSYFHCMNSQLFSIGMFSYVMLASSPLFCSPEWPRKLVSYCPRRLQQLLPLKAAPQPSVSCVY
KRSRGKSGQKPGLRHQLGAAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGY
LNPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAAWSPFQRTSWVQPL
LMDLSPWRAKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGE
YHKVYTTSPSPSCYMYVYVNTTELALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQR
LQEIERRRNTPFHERFFRFLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGELNPSNTDSSHSN
PPESNPDPVHSEF
;
26 
2 UNP TMG2_HUMAN O14669 ? 2 
;EETDQEVFLGPPEAQSFLSSHTRIPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYIYNGKGGRG
RVDVASLAVGLTGGILLIVLAGLGAFWYLRWRQHRG
;
24 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9BVP A 1 ? 733 ? P38435 26 ? 758 ? 26 758 
2 2 9BVP P 1 ? 116 ? O14669 24 ? 139 ? 24 139 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 7   ? GLY A 14  ? SER A 32  GLY A 39  1 ? 8  
HELX_P HELX_P2  AA2 GLU A 16  ? SER A 21  ? GLU A 41  SER A 46  5 ? 6  
HELX_P HELX_P3  AA3 SER A 22  ? ASN A 31  ? SER A 47  ASN A 56  1 ? 10 
HELX_P HELX_P4  AA4 PRO A 36  ? ILE A 54  ? PRO A 61  ILE A 79  1 ? 19 
HELX_P HELX_P5  AA5 SER A 62  ? LYS A 66  ? SER A 87  LYS A 91  5 ? 5  
HELX_P HELX_P6  AA6 PRO A 86  ? GLY A 107 ? PRO A 111 GLY A 132 1 ? 22 
HELX_P HELX_P7  AA7 CYS A 109 ? ASP A 128 ? CYS A 134 ASP A 153 1 ? 20 
HELX_P HELX_P8  AA8 LYS A 129 ? TRP A 132 ? LYS A 154 TRP A 157 5 ? 4  
HELX_P HELX_P9  AA9 ASN A 133 ? THR A 147 ? ASN A 158 THR A 172 1 ? 15 
HELX_P HELX_P10 AB1 SER A 156 ? ASN A 162 ? SER A 181 ASN A 187 1 ? 7  
HELX_P HELX_P11 AB2 ALA A 163 ? ARG A 166 ? ALA A 188 ARG A 191 5 ? 4  
HELX_P HELX_P12 AB3 LEU A 172 ? LYS A 193 ? LEU A 197 LYS A 218 1 ? 22 
HELX_P HELX_P13 AB4 ASP A 195 ? GLU A 200 ? ASP A 220 GLU A 225 1 ? 6  
HELX_P HELX_P14 AB5 TYR A 206 ? LEU A 219 ? TYR A 231 LEU A 244 5 ? 14 
HELX_P HELX_P15 AB6 SER A 221 ? VAL A 229 ? SER A 246 VAL A 254 1 ? 9  
HELX_P HELX_P16 AB7 HIS A 231 ? LEU A 245 ? HIS A 256 LEU A 270 1 ? 15 
HELX_P HELX_P17 AB8 SER A 250 ? PHE A 269 ? SER A 275 PHE A 294 1 ? 20 
HELX_P HELX_P18 AB9 MET A 273 ? SER A 282 ? MET A 298 SER A 307 1 ? 10 
HELX_P HELX_P19 AC1 PRO A 283 ? CYS A 286 ? PRO A 308 CYS A 311 5 ? 4  
HELX_P HELX_P20 AC2 GLU A 289 ? TYR A 297 ? GLU A 314 TYR A 322 1 ? 9  
HELX_P HELX_P21 AC3 PRO A 299 ? GLN A 304 ? PRO A 324 GLN A 329 1 ? 6  
HELX_P HELX_P22 AC4 LEU A 333 ? LEU A 352 ? LEU A 358 LEU A 377 1 ? 20 
HELX_P HELX_P23 AC5 PRO A 353 ? SER A 355 ? PRO A 378 SER A 380 5 ? 3  
HELX_P HELX_P24 AC6 HIS A 415 ? LEU A 430 ? HIS A 440 LEU A 455 1 ? 16 
HELX_P HELX_P25 AC7 PRO A 431 ? ASN A 434 ? PRO A 456 ASN A 459 5 ? 4  
HELX_P HELX_P26 AC8 LEU A 481 ? SER A 485 ? LEU A 506 SER A 510 5 ? 5  
HELX_P HELX_P27 AC9 PRO A 486 ? SER A 496 ? PRO A 511 SER A 521 1 ? 11 
HELX_P HELX_P28 AD1 ASN A 580 ? ASN A 602 ? ASN A 605 ASN A 627 1 ? 23 
HELX_P HELX_P29 AD2 PRO A 610 ? GLU A 612 ? PRO A 635 GLU A 637 5 ? 3  
HELX_P HELX_P30 AD3 LEU A 613 ? GLY A 619 ? LEU A 638 GLY A 644 1 ? 7  
HELX_P HELX_P31 AD4 THR A 628 ? ASN A 649 ? THR A 653 ASN A 674 1 ? 22 
HELX_P HELX_P32 AD5 PRO A 651 ? GLY A 684 ? PRO A 676 GLY A 709 1 ? 34 
HELX_P HELX_P33 AD6 SER A 687 ? ASN A 699 ? SER A 712 ASN A 724 1 ? 13 
HELX_P HELX_P34 AD7 GLY B 10  ? GLN B 15  ? GLY P 33  GLN P 38  1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 74  SG  ? ? ? 1_555 A CYS 425 SG ? ? A CYS 99  A CYS 450 1_555 ? ? ? ? ? ? ? 2.028 ? ?               
covale1 covale one  ? A ASN 434 ND2 ? ? ? 1_555 I NAG .   C1 ? ? A ASN 459 A NAG 804 1_555 ? ? ? ? ? ? ? 1.451 ? N-Glycosylation 
covale2 covale one  ? A ASN 525 ND2 ? ? ? 1_555 D NAG .   C1 ? ? A ASN 550 C NAG 1   1_555 ? ? ? ? ? ? ? 1.495 ? N-Glycosylation 
covale3 covale one  ? A ASN 545 ND2 ? ? ? 1_555 C NAG .   C1 ? ? A ASN 570 B NAG 1   1_555 ? ? ? ? ? ? ? 1.441 ? N-Glycosylation 
covale4 covale one  ? A ASN 580 ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 605 D NAG 1   1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale5 covale both ? C NAG .   O4  ? ? ? 1_555 C NAG .   C1 ? ? B NAG 1   B NAG 2   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
covale6 covale both ? D NAG .   O4  ? ? ? 1_555 D NAG .   C1 ? ? C NAG 1   C NAG 2   1_555 ? ? ? ? ? ? ? 1.439 ? ?               
covale7 covale both ? E NAG .   O4  ? ? ? 1_555 E NAG .   C1 ? ? D NAG 1   D NAG 2   1_555 ? ? ? ? ? ? ? 1.439 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG C .  ? ASN A 545 ? NAG B 1   ? 1_555 ASN A 570 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 NAG D .  ? ASN A 525 ? NAG C 1   ? 1_555 ASN A 550 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3 NAG E .  ? ASN A 580 ? NAG D 1   ? 1_555 ASN A 605 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4 NAG I .  ? ASN A 434 ? NAG A 804 ? 1_555 ASN A 459 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5 CYS A 74 ? CYS A 425 ? CYS A 99  ? 1_555 CYS A 450 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PRO A 33  ? THR A 34  ? PRO A 58  THR A 59  
AA1 2 VAL A 170 ? PRO A 171 ? VAL A 195 PRO A 196 
AA2 1 LEU A 398 ? LEU A 401 ? LEU A 423 LEU A 426 
AA2 2 ARG A 381 ? ARG A 391 ? ARG A 406 ARG A 416 
AA2 3 GLN A 439 ? ILE A 448 ? GLN A 464 ILE A 473 
AA2 4 GLN A 454 ? ARG A 455 ? GLN A 479 ARG A 480 
AA3 1 GLU A 503 ? ASP A 509 ? GLU A 528 ASP A 534 
AA3 2 SER A 572 ? TYR A 578 ? SER A 597 TYR A 603 
AA3 3 SER A 527 ? GLN A 532 ? SER A 552 GLN A 557 
AA3 4 LYS A 553 ? GLN A 555 ? LYS A 578 GLN A 580 
AA4 1 HIS A 514 ? PHE A 518 ? HIS A 539 PHE A 543 
AA4 2 TYR A 561 ? THR A 566 ? TYR A 586 THR A 591 
AA4 3 VAL A 535 ? LEU A 539 ? VAL A 560 LEU A 564 
AA4 4 LYS A 544 ? LEU A 548 ? LYS A 569 LEU A 573 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR A 34  ? N THR A 59  O VAL A 170 ? O VAL A 195 
AA2 1 2 O GLY A 399 ? O GLY A 424 N TYR A 390 ? N TYR A 415 
AA2 2 3 N LYS A 387 ? N LYS A 412 O ASP A 443 ? O ASP A 468 
AA2 3 4 N VAL A 446 ? N VAL A 471 O GLN A 454 ? O GLN A 479 
AA3 1 2 N ILE A 507 ? N ILE A 532 O TYR A 574 ? O TYR A 599 
AA3 2 3 O VAL A 577 ? O VAL A 602 N SER A 527 ? N SER A 552 
AA3 3 4 N ILE A 528 ? N ILE A 553 O MET A 554 ? O MET A 579 
AA4 1 2 N ASN A 517 ? N ASN A 542 O HIS A 562 ? O HIS A 587 
AA4 2 3 O LYS A 563 ? O LYS A 588 N GLU A 538 ? N GLU A 563 
AA4 3 4 N LEU A 539 ? N LEU A 564 O LYS A 544 ? O LYS A 569 
# 
_pdbx_entry_details.entry_id                   9BVP 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 ND2 A ASN 605 ? ? O5 D NAG 1   ? ? 1.70 
2 1 ND2 A ASN 459 ? ? O5 A NAG 804 ? ? 1.87 
3 1 O4  D NAG 1   ? ? O5 D NAG 2   ? ? 2.01 
4 1 O4  B NAG 1   ? ? O5 B NAG 2   ? ? 2.04 
5 1 O4  C NAG 1   ? ? O5 C NAG 2   ? ? 2.07 
6 1 ND2 A ASN 570 ? ? O5 B NAG 1   ? ? 2.10 
7 1 ND2 A ASN 459 ? ? C2 A NAG 804 ? ? 2.11 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 HIS A 256 ? ? -93.38  -60.10  
2 1 ASN A 389 ? ? -148.28 -159.31 
3 1 THR A 461 ? ? -78.16  -167.33 
4 1 GLU A 462 ? ? -56.48  106.44  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9BVP 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      OTHER 
# 
_em_3d_reconstruction.entry_id                    9BVP 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               171392 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
;Vitamin K-dependent gamma-carboxylase with Transmembrane gamma-carboxyglutamic acid protein 2 propeptide and Glu-rech region and with vitamin K hydroquinone
;
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_image_scans.entry_id                9BVP 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        5760 
_em_image_scans.dimension_width         4092 
_em_image_scans.frames_per_image        ? 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        9BVP 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           130000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   63 
_em_imaging.recording_temperature_maximum   77 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            50.0 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9BVP 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              95 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   283.15 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9BVP 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A SER 26  ? A SER 1   
2   1 Y 1 A GLY 27  ? A GLY 2   
3   1 Y 1 A PRO 28  ? A PRO 3   
4   1 Y 1 A ARG 29  ? A ARG 4   
5   1 Y 1 A GLN 30  ? A GLN 5   
6   1 Y 1 A SER 348 ? A SER 323 
7   1 Y 1 A ARG 349 ? A ARG 324 
8   1 Y 1 A GLY 350 ? A GLY 325 
9   1 Y 1 A LYS 351 ? A LYS 326 
10  1 Y 1 A SER 352 ? A SER 327 
11  1 Y 1 A GLU 729 ? A GLU 704 
12  1 Y 1 A ALA 730 ? A ALA 705 
13  1 Y 1 A VAL 731 ? A VAL 706 
14  1 Y 1 A GLY 732 ? A GLY 707 
15  1 Y 1 A GLU 733 ? A GLU 708 
16  1 Y 1 A LEU 734 ? A LEU 709 
17  1 Y 1 A ASN 735 ? A ASN 710 
18  1 Y 1 A PRO 736 ? A PRO 711 
19  1 Y 1 A SER 737 ? A SER 712 
20  1 Y 1 A ASN 738 ? A ASN 713 
21  1 Y 1 A THR 739 ? A THR 714 
22  1 Y 1 A ASP 740 ? A ASP 715 
23  1 Y 1 A SER 741 ? A SER 716 
24  1 Y 1 A SER 742 ? A SER 717 
25  1 Y 1 A HIS 743 ? A HIS 718 
26  1 Y 1 A SER 744 ? A SER 719 
27  1 Y 1 A ASN 745 ? A ASN 720 
28  1 Y 1 A PRO 746 ? A PRO 721 
29  1 Y 1 A PRO 747 ? A PRO 722 
30  1 Y 1 A GLU 748 ? A GLU 723 
31  1 Y 1 A SER 749 ? A SER 724 
32  1 Y 1 A ASN 750 ? A ASN 725 
33  1 Y 1 A PRO 751 ? A PRO 726 
34  1 Y 1 A ASP 752 ? A ASP 727 
35  1 Y 1 A PRO 753 ? A PRO 728 
36  1 Y 1 A VAL 754 ? A VAL 729 
37  1 Y 1 A HIS 755 ? A HIS 730 
38  1 Y 1 A SER 756 ? A SER 731 
39  1 Y 1 A GLU 757 ? A GLU 732 
40  1 Y 1 A PHE 758 ? A PHE 733 
41  1 Y 1 P ARG 46  ? B ARG 23  
42  1 Y 1 P ILE 47  ? B ILE 24  
43  1 Y 1 P PRO 48  ? B PRO 25  
44  1 Y 1 P ARG 49  ? B ARG 26  
45  1 Y 1 P ALA 50  ? B ALA 27  
46  1 Y 1 P ASN 51  ? B ASN 28  
47  1 Y 1 P HIS 52  ? B HIS 29  
48  1 Y 1 P TRP 53  ? B TRP 30  
49  1 Y 1 P ASP 54  ? B ASP 31  
50  1 Y 1 P LEU 55  ? B LEU 32  
51  1 Y 1 P GLU 56  ? B GLU 33  
52  1 Y 1 P LEU 57  ? B LEU 34  
53  1 Y 1 P LEU 58  ? B LEU 35  
54  1 Y 1 P THR 59  ? B THR 36  
55  1 Y 1 P PRO 60  ? B PRO 37  
56  1 Y 1 P GLY 61  ? B GLY 38  
57  1 Y 1 P ASN 62  ? B ASN 39  
58  1 Y 1 P LEU 63  ? B LEU 40  
59  1 Y 1 P GLU 64  ? B GLU 41  
60  1 Y 1 P ARG 65  ? B ARG 42  
61  1 Y 1 P GLU 66  ? B GLU 43  
62  1 Y 1 P CYS 67  ? B CYS 44  
63  1 Y 1 P LEU 68  ? B LEU 45  
64  1 Y 1 P GLU 69  ? B GLU 46  
65  1 Y 1 P GLU 70  ? B GLU 47  
66  1 Y 1 P ARG 71  ? B ARG 48  
67  1 Y 1 P CYS 72  ? B CYS 49  
68  1 Y 1 P SER 73  ? B SER 50  
69  1 Y 1 P TRP 74  ? B TRP 51  
70  1 Y 1 P GLU 75  ? B GLU 52  
71  1 Y 1 P GLU 76  ? B GLU 53  
72  1 Y 1 P ALA 77  ? B ALA 54  
73  1 Y 1 P ARG 78  ? B ARG 55  
74  1 Y 1 P GLU 79  ? B GLU 56  
75  1 Y 1 P TYR 80  ? B TYR 57  
76  1 Y 1 P PHE 81  ? B PHE 58  
77  1 Y 1 P GLU 82  ? B GLU 59  
78  1 Y 1 P ASP 83  ? B ASP 60  
79  1 Y 1 P ASN 84  ? B ASN 61  
80  1 Y 1 P THR 85  ? B THR 62  
81  1 Y 1 P LYS 99  ? B LYS 76  
82  1 Y 1 P GLY 100 ? B GLY 77  
83  1 Y 1 P GLY 101 ? B GLY 78  
84  1 Y 1 P ARG 102 ? B ARG 79  
85  1 Y 1 P GLY 103 ? B GLY 80  
86  1 Y 1 P ARG 104 ? B ARG 81  
87  1 Y 1 P VAL 105 ? B VAL 82  
88  1 Y 1 P ASP 106 ? B ASP 83  
89  1 Y 1 P VAL 107 ? B VAL 84  
90  1 Y 1 P ALA 108 ? B ALA 85  
91  1 Y 1 P SER 109 ? B SER 86  
92  1 Y 1 P LEU 110 ? B LEU 87  
93  1 Y 1 P ALA 111 ? B ALA 88  
94  1 Y 1 P VAL 112 ? B VAL 89  
95  1 Y 1 P GLY 113 ? B GLY 90  
96  1 Y 1 P LEU 114 ? B LEU 91  
97  1 Y 1 P THR 115 ? B THR 92  
98  1 Y 1 P GLY 116 ? B GLY 93  
99  1 Y 1 P GLY 117 ? B GLY 94  
100 1 Y 1 P ILE 118 ? B ILE 95  
101 1 Y 1 P LEU 119 ? B LEU 96  
102 1 Y 1 P LEU 120 ? B LEU 97  
103 1 Y 1 P ILE 121 ? B ILE 98  
104 1 Y 1 P VAL 122 ? B VAL 99  
105 1 Y 1 P LEU 123 ? B LEU 100 
106 1 Y 1 P ALA 124 ? B ALA 101 
107 1 Y 1 P GLY 125 ? B GLY 102 
108 1 Y 1 P LEU 126 ? B LEU 103 
109 1 Y 1 P GLY 127 ? B GLY 104 
110 1 Y 1 P ALA 128 ? B ALA 105 
111 1 Y 1 P PHE 129 ? B PHE 106 
112 1 Y 1 P TRP 130 ? B TRP 107 
113 1 Y 1 P TYR 131 ? B TYR 108 
114 1 Y 1 P LEU 132 ? B LEU 109 
115 1 Y 1 P ARG 133 ? B ARG 110 
116 1 Y 1 P TRP 134 ? B TRP 111 
117 1 Y 1 P ARG 135 ? B ARG 112 
118 1 Y 1 P GLN 136 ? B GLN 113 
119 1 Y 1 P HIS 137 ? B HIS 114 
120 1 Y 1 P ARG 138 ? B ARG 115 
121 1 Y 1 P GLY 139 ? B GLY 116 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
6PL   C26  C N N 1   
6PL   C25  C N N 2   
6PL   C24  C N N 3   
6PL   C23  C N N 4   
6PL   C22  C N N 5   
6PL   C21  C N N 6   
6PL   C20  C N N 7   
6PL   C19  C N N 8   
6PL   C18  C N N 9   
6PL   C17  C N N 10  
6PL   C16  C N N 11  
6PL   C15  C N N 12  
6PL   C14  C N N 13  
6PL   C13  C N N 14  
6PL   C12  C N N 15  
6PL   C11  C N N 16  
6PL   O11  O N N 17  
6PL   O3   O N N 18  
6PL   C3   C N N 19  
6PL   C2   C N R 20  
6PL   C1   C N N 21  
6PL   O3P  O N N 22  
6PL   P    P N S 23  
6PL   O1P  O N N 24  
6PL   O2P  O N N 25  
6PL   O4P  O N N 26  
6PL   C4   C N N 27  
6PL   C5   C N N 28  
6PL   N    N N N 29  
6PL   C7   C N N 30  
6PL   C8   C N N 31  
6PL   C6   C N N 32  
6PL   O2   O N N 33  
6PL   C31  C N N 34  
6PL   O31  O N N 35  
6PL   C32  C N N 36  
6PL   C33  C N N 37  
6PL   C34  C N N 38  
6PL   C35  C N N 39  
6PL   C36  C N N 40  
6PL   C37  C N N 41  
6PL   C38  C N N 42  
6PL   C39  C N N 43  
6PL   C40  C N N 44  
6PL   C41  C N N 45  
6PL   C42  C N N 46  
6PL   C43  C N N 47  
6PL   C44  C N N 48  
6PL   C45  C N N 49  
6PL   C46  C N N 50  
6PL   C47  C N N 51  
6PL   C48  C N N 52  
6PL   H261 H N N 53  
6PL   H262 H N N 54  
6PL   H263 H N N 55  
6PL   H251 H N N 56  
6PL   H252 H N N 57  
6PL   H241 H N N 58  
6PL   H242 H N N 59  
6PL   H231 H N N 60  
6PL   H232 H N N 61  
6PL   H221 H N N 62  
6PL   H222 H N N 63  
6PL   H211 H N N 64  
6PL   H212 H N N 65  
6PL   H201 H N N 66  
6PL   H202 H N N 67  
6PL   H191 H N N 68  
6PL   H192 H N N 69  
6PL   H181 H N N 70  
6PL   H182 H N N 71  
6PL   H171 H N N 72  
6PL   H172 H N N 73  
6PL   H161 H N N 74  
6PL   H162 H N N 75  
6PL   H151 H N N 76  
6PL   H152 H N N 77  
6PL   H141 H N N 78  
6PL   H142 H N N 79  
6PL   H131 H N N 80  
6PL   H132 H N N 81  
6PL   H121 H N N 82  
6PL   H122 H N N 83  
6PL   H31  H N N 84  
6PL   H32  H N N 85  
6PL   H2   H N N 86  
6PL   H11  H N N 87  
6PL   H12  H N N 88  
6PL   H2P  H N N 89  
6PL   H41  H N N 90  
6PL   H42  H N N 91  
6PL   H51  H N N 92  
6PL   H52  H N N 93  
6PL   H71  H N N 94  
6PL   H72  H N N 95  
6PL   H73  H N N 96  
6PL   H81  H N N 97  
6PL   H82  H N N 98  
6PL   H83  H N N 99  
6PL   H61  H N N 100 
6PL   H62  H N N 101 
6PL   H63  H N N 102 
6PL   H321 H N N 103 
6PL   H322 H N N 104 
6PL   H331 H N N 105 
6PL   H332 H N N 106 
6PL   H341 H N N 107 
6PL   H342 H N N 108 
6PL   H351 H N N 109 
6PL   H352 H N N 110 
6PL   H361 H N N 111 
6PL   H362 H N N 112 
6PL   H371 H N N 113 
6PL   H372 H N N 114 
6PL   H381 H N N 115 
6PL   H382 H N N 116 
6PL   H391 H N N 117 
6PL   H392 H N N 118 
6PL   H401 H N N 119 
6PL   H402 H N N 120 
6PL   H411 H N N 121 
6PL   H412 H N N 122 
6PL   H421 H N N 123 
6PL   H422 H N N 124 
6PL   H431 H N N 125 
6PL   H432 H N N 126 
6PL   H441 H N N 127 
6PL   H442 H N N 128 
6PL   H451 H N N 129 
6PL   H452 H N N 130 
6PL   H461 H N N 131 
6PL   H462 H N N 132 
6PL   H471 H N N 133 
6PL   H472 H N N 134 
6PL   H481 H N N 135 
6PL   H482 H N N 136 
6PL   H483 H N N 137 
A1AVC C11  C Y N 138 
A1AVC C12  C N N 139 
A1AVC C13  C N N 140 
A1AVC C14  C N N 141 
A1AVC C15  C N N 142 
A1AVC C16  C N N 143 
A1AVC C01  C N N 144 
A1AVC C02  C Y N 145 
A1AVC C03  C Y N 146 
A1AVC C04  C Y N 147 
A1AVC C05  C Y N 148 
A1AVC C06  C Y N 149 
A1AVC C07  C Y N 150 
A1AVC C08  C Y N 151 
A1AVC C09  C Y N 152 
A1AVC C10  C Y N 153 
A1AVC C17  C N N 154 
A1AVC C18  C N N 155 
A1AVC C19  C N R 156 
A1AVC C20  C N N 157 
A1AVC C21  C N N 158 
A1AVC C22  C N N 159 
A1AVC C23  C N N 160 
A1AVC C24  C N R 161 
A1AVC C25  C N N 162 
A1AVC C26  C N N 163 
A1AVC C27  C N N 164 
A1AVC C28  C N N 165 
A1AVC C29  C N N 166 
A1AVC C30  C N N 167 
A1AVC C31  C N N 168 
A1AVC O32  O N N 169 
A1AVC O33  O N N 170 
A1AVC H1   H N N 171 
A1AVC H2   H N N 172 
A1AVC H3   H N N 173 
A1AVC H4   H N N 174 
A1AVC H5   H N N 175 
A1AVC H6   H N N 176 
A1AVC H7   H N N 177 
A1AVC H8   H N N 178 
A1AVC H9   H N N 179 
A1AVC H10  H N N 180 
A1AVC H11  H N N 181 
A1AVC H12  H N N 182 
A1AVC H13  H N N 183 
A1AVC H14  H N N 184 
A1AVC H15  H N N 185 
A1AVC H16  H N N 186 
A1AVC H17  H N N 187 
A1AVC H18  H N N 188 
A1AVC H19  H N N 189 
A1AVC H20  H N N 190 
A1AVC H21  H N N 191 
A1AVC H22  H N N 192 
A1AVC H23  H N N 193 
A1AVC H24  H N N 194 
A1AVC H25  H N N 195 
A1AVC H26  H N N 196 
A1AVC H27  H N N 197 
A1AVC H28  H N N 198 
A1AVC H29  H N N 199 
A1AVC H30  H N N 200 
A1AVC H31  H N N 201 
A1AVC H32  H N N 202 
A1AVC H33  H N N 203 
A1AVC H34  H N N 204 
A1AVC H35  H N N 205 
A1AVC H36  H N N 206 
A1AVC H37  H N N 207 
A1AVC H38  H N N 208 
A1AVC H39  H N N 209 
A1AVC H40  H N N 210 
A1AVC H41  H N N 211 
A1AVC H42  H N N 212 
A1AVC H43  H N N 213 
A1AVC H44  H N N 214 
A1AVC H45  H N N 215 
A1AVC H46  H N N 216 
A1AVC H47  H N N 217 
A1AVC H48  H N N 218 
ALA   N    N N N 219 
ALA   CA   C N S 220 
ALA   C    C N N 221 
ALA   O    O N N 222 
ALA   CB   C N N 223 
ALA   OXT  O N N 224 
ALA   H    H N N 225 
ALA   H2   H N N 226 
ALA   HA   H N N 227 
ALA   HB1  H N N 228 
ALA   HB2  H N N 229 
ALA   HB3  H N N 230 
ALA   HXT  H N N 231 
ARG   N    N N N 232 
ARG   CA   C N S 233 
ARG   C    C N N 234 
ARG   O    O N N 235 
ARG   CB   C N N 236 
ARG   CG   C N N 237 
ARG   CD   C N N 238 
ARG   NE   N N N 239 
ARG   CZ   C N N 240 
ARG   NH1  N N N 241 
ARG   NH2  N N N 242 
ARG   OXT  O N N 243 
ARG   H    H N N 244 
ARG   H2   H N N 245 
ARG   HA   H N N 246 
ARG   HB2  H N N 247 
ARG   HB3  H N N 248 
ARG   HG2  H N N 249 
ARG   HG3  H N N 250 
ARG   HD2  H N N 251 
ARG   HD3  H N N 252 
ARG   HE   H N N 253 
ARG   HH11 H N N 254 
ARG   HH12 H N N 255 
ARG   HH21 H N N 256 
ARG   HH22 H N N 257 
ARG   HXT  H N N 258 
ASN   N    N N N 259 
ASN   CA   C N S 260 
ASN   C    C N N 261 
ASN   O    O N N 262 
ASN   CB   C N N 263 
ASN   CG   C N N 264 
ASN   OD1  O N N 265 
ASN   ND2  N N N 266 
ASN   OXT  O N N 267 
ASN   H    H N N 268 
ASN   H2   H N N 269 
ASN   HA   H N N 270 
ASN   HB2  H N N 271 
ASN   HB3  H N N 272 
ASN   HD21 H N N 273 
ASN   HD22 H N N 274 
ASN   HXT  H N N 275 
ASP   N    N N N 276 
ASP   CA   C N S 277 
ASP   C    C N N 278 
ASP   O    O N N 279 
ASP   CB   C N N 280 
ASP   CG   C N N 281 
ASP   OD1  O N N 282 
ASP   OD2  O N N 283 
ASP   OXT  O N N 284 
ASP   H    H N N 285 
ASP   H2   H N N 286 
ASP   HA   H N N 287 
ASP   HB2  H N N 288 
ASP   HB3  H N N 289 
ASP   HD2  H N N 290 
ASP   HXT  H N N 291 
CYS   N    N N N 292 
CYS   CA   C N R 293 
CYS   C    C N N 294 
CYS   O    O N N 295 
CYS   CB   C N N 296 
CYS   SG   S N N 297 
CYS   OXT  O N N 298 
CYS   H    H N N 299 
CYS   H2   H N N 300 
CYS   HA   H N N 301 
CYS   HB2  H N N 302 
CYS   HB3  H N N 303 
CYS   HG   H N N 304 
CYS   HXT  H N N 305 
GLN   N    N N N 306 
GLN   CA   C N S 307 
GLN   C    C N N 308 
GLN   O    O N N 309 
GLN   CB   C N N 310 
GLN   CG   C N N 311 
GLN   CD   C N N 312 
GLN   OE1  O N N 313 
GLN   NE2  N N N 314 
GLN   OXT  O N N 315 
GLN   H    H N N 316 
GLN   H2   H N N 317 
GLN   HA   H N N 318 
GLN   HB2  H N N 319 
GLN   HB3  H N N 320 
GLN   HG2  H N N 321 
GLN   HG3  H N N 322 
GLN   HE21 H N N 323 
GLN   HE22 H N N 324 
GLN   HXT  H N N 325 
GLU   N    N N N 326 
GLU   CA   C N S 327 
GLU   C    C N N 328 
GLU   O    O N N 329 
GLU   CB   C N N 330 
GLU   CG   C N N 331 
GLU   CD   C N N 332 
GLU   OE1  O N N 333 
GLU   OE2  O N N 334 
GLU   OXT  O N N 335 
GLU   H    H N N 336 
GLU   H2   H N N 337 
GLU   HA   H N N 338 
GLU   HB2  H N N 339 
GLU   HB3  H N N 340 
GLU   HG2  H N N 341 
GLU   HG3  H N N 342 
GLU   HE2  H N N 343 
GLU   HXT  H N N 344 
GLY   N    N N N 345 
GLY   CA   C N N 346 
GLY   C    C N N 347 
GLY   O    O N N 348 
GLY   OXT  O N N 349 
GLY   H    H N N 350 
GLY   H2   H N N 351 
GLY   HA2  H N N 352 
GLY   HA3  H N N 353 
GLY   HXT  H N N 354 
HIS   N    N N N 355 
HIS   CA   C N S 356 
HIS   C    C N N 357 
HIS   O    O N N 358 
HIS   CB   C N N 359 
HIS   CG   C Y N 360 
HIS   ND1  N Y N 361 
HIS   CD2  C Y N 362 
HIS   CE1  C Y N 363 
HIS   NE2  N Y N 364 
HIS   OXT  O N N 365 
HIS   H    H N N 366 
HIS   H2   H N N 367 
HIS   HA   H N N 368 
HIS   HB2  H N N 369 
HIS   HB3  H N N 370 
HIS   HD1  H N N 371 
HIS   HD2  H N N 372 
HIS   HE1  H N N 373 
HIS   HE2  H N N 374 
HIS   HXT  H N N 375 
ILE   N    N N N 376 
ILE   CA   C N S 377 
ILE   C    C N N 378 
ILE   O    O N N 379 
ILE   CB   C N S 380 
ILE   CG1  C N N 381 
ILE   CG2  C N N 382 
ILE   CD1  C N N 383 
ILE   OXT  O N N 384 
ILE   H    H N N 385 
ILE   H2   H N N 386 
ILE   HA   H N N 387 
ILE   HB   H N N 388 
ILE   HG12 H N N 389 
ILE   HG13 H N N 390 
ILE   HG21 H N N 391 
ILE   HG22 H N N 392 
ILE   HG23 H N N 393 
ILE   HD11 H N N 394 
ILE   HD12 H N N 395 
ILE   HD13 H N N 396 
ILE   HXT  H N N 397 
LEU   N    N N N 398 
LEU   CA   C N S 399 
LEU   C    C N N 400 
LEU   O    O N N 401 
LEU   CB   C N N 402 
LEU   CG   C N N 403 
LEU   CD1  C N N 404 
LEU   CD2  C N N 405 
LEU   OXT  O N N 406 
LEU   H    H N N 407 
LEU   H2   H N N 408 
LEU   HA   H N N 409 
LEU   HB2  H N N 410 
LEU   HB3  H N N 411 
LEU   HG   H N N 412 
LEU   HD11 H N N 413 
LEU   HD12 H N N 414 
LEU   HD13 H N N 415 
LEU   HD21 H N N 416 
LEU   HD22 H N N 417 
LEU   HD23 H N N 418 
LEU   HXT  H N N 419 
LYS   N    N N N 420 
LYS   CA   C N S 421 
LYS   C    C N N 422 
LYS   O    O N N 423 
LYS   CB   C N N 424 
LYS   CG   C N N 425 
LYS   CD   C N N 426 
LYS   CE   C N N 427 
LYS   NZ   N N N 428 
LYS   OXT  O N N 429 
LYS   H    H N N 430 
LYS   H2   H N N 431 
LYS   HA   H N N 432 
LYS   HB2  H N N 433 
LYS   HB3  H N N 434 
LYS   HG2  H N N 435 
LYS   HG3  H N N 436 
LYS   HD2  H N N 437 
LYS   HD3  H N N 438 
LYS   HE2  H N N 439 
LYS   HE3  H N N 440 
LYS   HZ1  H N N 441 
LYS   HZ2  H N N 442 
LYS   HZ3  H N N 443 
LYS   HXT  H N N 444 
MET   N    N N N 445 
MET   CA   C N S 446 
MET   C    C N N 447 
MET   O    O N N 448 
MET   CB   C N N 449 
MET   CG   C N N 450 
MET   SD   S N N 451 
MET   CE   C N N 452 
MET   OXT  O N N 453 
MET   H    H N N 454 
MET   H2   H N N 455 
MET   HA   H N N 456 
MET   HB2  H N N 457 
MET   HB3  H N N 458 
MET   HG2  H N N 459 
MET   HG3  H N N 460 
MET   HE1  H N N 461 
MET   HE2  H N N 462 
MET   HE3  H N N 463 
MET   HXT  H N N 464 
NAG   C1   C N R 465 
NAG   C2   C N R 466 
NAG   C3   C N R 467 
NAG   C4   C N S 468 
NAG   C5   C N R 469 
NAG   C6   C N N 470 
NAG   C7   C N N 471 
NAG   C8   C N N 472 
NAG   N2   N N N 473 
NAG   O1   O N N 474 
NAG   O3   O N N 475 
NAG   O4   O N N 476 
NAG   O5   O N N 477 
NAG   O6   O N N 478 
NAG   O7   O N N 479 
NAG   H1   H N N 480 
NAG   H2   H N N 481 
NAG   H3   H N N 482 
NAG   H4   H N N 483 
NAG   H5   H N N 484 
NAG   H61  H N N 485 
NAG   H62  H N N 486 
NAG   H81  H N N 487 
NAG   H82  H N N 488 
NAG   H83  H N N 489 
NAG   HN2  H N N 490 
NAG   HO1  H N N 491 
NAG   HO3  H N N 492 
NAG   HO4  H N N 493 
NAG   HO6  H N N 494 
PHE   N    N N N 495 
PHE   CA   C N S 496 
PHE   C    C N N 497 
PHE   O    O N N 498 
PHE   CB   C N N 499 
PHE   CG   C Y N 500 
PHE   CD1  C Y N 501 
PHE   CD2  C Y N 502 
PHE   CE1  C Y N 503 
PHE   CE2  C Y N 504 
PHE   CZ   C Y N 505 
PHE   OXT  O N N 506 
PHE   H    H N N 507 
PHE   H2   H N N 508 
PHE   HA   H N N 509 
PHE   HB2  H N N 510 
PHE   HB3  H N N 511 
PHE   HD1  H N N 512 
PHE   HD2  H N N 513 
PHE   HE1  H N N 514 
PHE   HE2  H N N 515 
PHE   HZ   H N N 516 
PHE   HXT  H N N 517 
PRO   N    N N N 518 
PRO   CA   C N S 519 
PRO   C    C N N 520 
PRO   O    O N N 521 
PRO   CB   C N N 522 
PRO   CG   C N N 523 
PRO   CD   C N N 524 
PRO   OXT  O N N 525 
PRO   H    H N N 526 
PRO   HA   H N N 527 
PRO   HB2  H N N 528 
PRO   HB3  H N N 529 
PRO   HG2  H N N 530 
PRO   HG3  H N N 531 
PRO   HD2  H N N 532 
PRO   HD3  H N N 533 
PRO   HXT  H N N 534 
SER   N    N N N 535 
SER   CA   C N S 536 
SER   C    C N N 537 
SER   O    O N N 538 
SER   CB   C N N 539 
SER   OG   O N N 540 
SER   OXT  O N N 541 
SER   H    H N N 542 
SER   H2   H N N 543 
SER   HA   H N N 544 
SER   HB2  H N N 545 
SER   HB3  H N N 546 
SER   HG   H N N 547 
SER   HXT  H N N 548 
THR   N    N N N 549 
THR   CA   C N S 550 
THR   C    C N N 551 
THR   O    O N N 552 
THR   CB   C N R 553 
THR   OG1  O N N 554 
THR   CG2  C N N 555 
THR   OXT  O N N 556 
THR   H    H N N 557 
THR   H2   H N N 558 
THR   HA   H N N 559 
THR   HB   H N N 560 
THR   HG1  H N N 561 
THR   HG21 H N N 562 
THR   HG22 H N N 563 
THR   HG23 H N N 564 
THR   HXT  H N N 565 
TRP   N    N N N 566 
TRP   CA   C N S 567 
TRP   C    C N N 568 
TRP   O    O N N 569 
TRP   CB   C N N 570 
TRP   CG   C Y N 571 
TRP   CD1  C Y N 572 
TRP   CD2  C Y N 573 
TRP   NE1  N Y N 574 
TRP   CE2  C Y N 575 
TRP   CE3  C Y N 576 
TRP   CZ2  C Y N 577 
TRP   CZ3  C Y N 578 
TRP   CH2  C Y N 579 
TRP   OXT  O N N 580 
TRP   H    H N N 581 
TRP   H2   H N N 582 
TRP   HA   H N N 583 
TRP   HB2  H N N 584 
TRP   HB3  H N N 585 
TRP   HD1  H N N 586 
TRP   HE1  H N N 587 
TRP   HE3  H N N 588 
TRP   HZ2  H N N 589 
TRP   HZ3  H N N 590 
TRP   HH2  H N N 591 
TRP   HXT  H N N 592 
TYR   N    N N N 593 
TYR   CA   C N S 594 
TYR   C    C N N 595 
TYR   O    O N N 596 
TYR   CB   C N N 597 
TYR   CG   C Y N 598 
TYR   CD1  C Y N 599 
TYR   CD2  C Y N 600 
TYR   CE1  C Y N 601 
TYR   CE2  C Y N 602 
TYR   CZ   C Y N 603 
TYR   OH   O N N 604 
TYR   OXT  O N N 605 
TYR   H    H N N 606 
TYR   H2   H N N 607 
TYR   HA   H N N 608 
TYR   HB2  H N N 609 
TYR   HB3  H N N 610 
TYR   HD1  H N N 611 
TYR   HD2  H N N 612 
TYR   HE1  H N N 613 
TYR   HE2  H N N 614 
TYR   HH   H N N 615 
TYR   HXT  H N N 616 
VAL   N    N N N 617 
VAL   CA   C N S 618 
VAL   C    C N N 619 
VAL   O    O N N 620 
VAL   CB   C N N 621 
VAL   CG1  C N N 622 
VAL   CG2  C N N 623 
VAL   OXT  O N N 624 
VAL   H    H N N 625 
VAL   H2   H N N 626 
VAL   HA   H N N 627 
VAL   HB   H N N 628 
VAL   HG11 H N N 629 
VAL   HG12 H N N 630 
VAL   HG13 H N N 631 
VAL   HG21 H N N 632 
VAL   HG22 H N N 633 
VAL   HG23 H N N 634 
VAL   HXT  H N N 635 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
6PL   C26 C25  sing N N 1   
6PL   C26 H261 sing N N 2   
6PL   C26 H262 sing N N 3   
6PL   C26 H263 sing N N 4   
6PL   C25 C24  sing N N 5   
6PL   C25 H251 sing N N 6   
6PL   C25 H252 sing N N 7   
6PL   C24 C23  sing N N 8   
6PL   C24 H241 sing N N 9   
6PL   C24 H242 sing N N 10  
6PL   C23 C22  sing N N 11  
6PL   C23 H231 sing N N 12  
6PL   C23 H232 sing N N 13  
6PL   C22 C21  sing N N 14  
6PL   C22 H221 sing N N 15  
6PL   C22 H222 sing N N 16  
6PL   C21 C20  sing N N 17  
6PL   C21 H211 sing N N 18  
6PL   C21 H212 sing N N 19  
6PL   C20 C19  sing N N 20  
6PL   C20 H201 sing N N 21  
6PL   C20 H202 sing N N 22  
6PL   C19 C18  sing N N 23  
6PL   C19 H191 sing N N 24  
6PL   C19 H192 sing N N 25  
6PL   C18 C17  sing N N 26  
6PL   C18 H181 sing N N 27  
6PL   C18 H182 sing N N 28  
6PL   C17 C16  sing N N 29  
6PL   C17 H171 sing N N 30  
6PL   C17 H172 sing N N 31  
6PL   C16 C15  sing N N 32  
6PL   C16 H161 sing N N 33  
6PL   C16 H162 sing N N 34  
6PL   C15 C14  sing N N 35  
6PL   C15 H151 sing N N 36  
6PL   C15 H152 sing N N 37  
6PL   C14 C13  sing N N 38  
6PL   C14 H141 sing N N 39  
6PL   C14 H142 sing N N 40  
6PL   C13 C12  sing N N 41  
6PL   C13 H131 sing N N 42  
6PL   C13 H132 sing N N 43  
6PL   C12 C11  sing N N 44  
6PL   C12 H121 sing N N 45  
6PL   C12 H122 sing N N 46  
6PL   C11 O11  doub N N 47  
6PL   C11 O3   sing N N 48  
6PL   O3  C3   sing N N 49  
6PL   C3  C2   sing N N 50  
6PL   C3  H31  sing N N 51  
6PL   C3  H32  sing N N 52  
6PL   C2  C1   sing N N 53  
6PL   C2  O2   sing N N 54  
6PL   C2  H2   sing N N 55  
6PL   C1  O3P  sing N N 56  
6PL   C1  H11  sing N N 57  
6PL   C1  H12  sing N N 58  
6PL   O3P P    sing N N 59  
6PL   P   O1P  doub N N 60  
6PL   P   O2P  sing N N 61  
6PL   P   O4P  sing N N 62  
6PL   O2P H2P  sing N N 63  
6PL   O4P C4   sing N N 64  
6PL   C4  C5   sing N N 65  
6PL   C4  H41  sing N N 66  
6PL   C4  H42  sing N N 67  
6PL   C5  N    sing N N 68  
6PL   C5  H51  sing N N 69  
6PL   C5  H52  sing N N 70  
6PL   N   C7   sing N N 71  
6PL   N   C8   sing N N 72  
6PL   N   C6   sing N N 73  
6PL   C7  H71  sing N N 74  
6PL   C7  H72  sing N N 75  
6PL   C7  H73  sing N N 76  
6PL   C8  H81  sing N N 77  
6PL   C8  H82  sing N N 78  
6PL   C8  H83  sing N N 79  
6PL   C6  H61  sing N N 80  
6PL   C6  H62  sing N N 81  
6PL   C6  H63  sing N N 82  
6PL   O2  C31  sing N N 83  
6PL   C31 O31  doub N N 84  
6PL   C31 C32  sing N N 85  
6PL   C32 C33  sing N N 86  
6PL   C32 H321 sing N N 87  
6PL   C32 H322 sing N N 88  
6PL   C33 C34  sing N N 89  
6PL   C33 H331 sing N N 90  
6PL   C33 H332 sing N N 91  
6PL   C34 C35  sing N N 92  
6PL   C34 H341 sing N N 93  
6PL   C34 H342 sing N N 94  
6PL   C35 C36  sing N N 95  
6PL   C35 H351 sing N N 96  
6PL   C35 H352 sing N N 97  
6PL   C36 C37  sing N N 98  
6PL   C36 H361 sing N N 99  
6PL   C36 H362 sing N N 100 
6PL   C37 C38  sing N N 101 
6PL   C37 H371 sing N N 102 
6PL   C37 H372 sing N N 103 
6PL   C38 C39  sing N N 104 
6PL   C38 H381 sing N N 105 
6PL   C38 H382 sing N N 106 
6PL   C39 C40  sing N N 107 
6PL   C39 H391 sing N N 108 
6PL   C39 H392 sing N N 109 
6PL   C40 C41  sing N N 110 
6PL   C40 H401 sing N N 111 
6PL   C40 H402 sing N N 112 
6PL   C41 C42  sing N N 113 
6PL   C41 H411 sing N N 114 
6PL   C41 H412 sing N N 115 
6PL   C42 C43  sing N N 116 
6PL   C42 H421 sing N N 117 
6PL   C42 H422 sing N N 118 
6PL   C43 C44  sing N N 119 
6PL   C43 H431 sing N N 120 
6PL   C43 H432 sing N N 121 
6PL   C44 C45  sing N N 122 
6PL   C44 H441 sing N N 123 
6PL   C44 H442 sing N N 124 
6PL   C45 C46  sing N N 125 
6PL   C45 H451 sing N N 126 
6PL   C45 H452 sing N N 127 
6PL   C46 C47  sing N N 128 
6PL   C46 H461 sing N N 129 
6PL   C46 H462 sing N N 130 
6PL   C47 C48  sing N N 131 
6PL   C47 H471 sing N N 132 
6PL   C47 H472 sing N N 133 
6PL   C48 H481 sing N N 134 
6PL   C48 H482 sing N N 135 
6PL   C48 H483 sing N N 136 
A1AVC C30 C29  sing N N 137 
A1AVC C29 C28  sing N N 138 
A1AVC C29 C31  sing N N 139 
A1AVC C28 C27  sing N N 140 
A1AVC C21 C22  sing N N 141 
A1AVC C21 C19  sing N N 142 
A1AVC C18 C17  sing N N 143 
A1AVC C18 C19  sing N N 144 
A1AVC C16 C17  sing N N 145 
A1AVC C16 C14  sing N N 146 
A1AVC C27 C26  sing N N 147 
A1AVC C15 C14  sing N N 148 
A1AVC C22 C23  sing N N 149 
A1AVC C14 C13  doub N E 150 
A1AVC C19 C20  sing N N 151 
A1AVC C26 C24  sing N N 152 
A1AVC C23 C24  sing N N 153 
A1AVC C13 C12  sing N N 154 
A1AVC C24 C25  sing N N 155 
A1AVC C12 C11  sing N N 156 
A1AVC O32 C10  sing N N 157 
A1AVC C11 C10  doub Y N 158 
A1AVC C11 C02  sing Y N 159 
A1AVC C01 C02  sing N N 160 
A1AVC C10 C09  sing Y N 161 
A1AVC C02 C03  doub Y N 162 
A1AVC C09 C08  sing Y N 163 
A1AVC C09 C04  doub Y N 164 
A1AVC C03 C04  sing Y N 165 
A1AVC C03 O33  sing N N 166 
A1AVC C08 C07  doub Y N 167 
A1AVC C04 C05  sing Y N 168 
A1AVC C07 C06  sing Y N 169 
A1AVC C05 C06  doub Y N 170 
A1AVC C12 H1   sing N N 171 
A1AVC C12 H2   sing N N 172 
A1AVC C13 H3   sing N N 173 
A1AVC C15 H4   sing N N 174 
A1AVC C15 H5   sing N N 175 
A1AVC C15 H6   sing N N 176 
A1AVC C16 H7   sing N N 177 
A1AVC C16 H8   sing N N 178 
A1AVC C01 H9   sing N N 179 
A1AVC C01 H10  sing N N 180 
A1AVC C01 H11  sing N N 181 
A1AVC C05 H12  sing N N 182 
A1AVC C06 H13  sing N N 183 
A1AVC C07 H14  sing N N 184 
A1AVC C08 H15  sing N N 185 
A1AVC C17 H16  sing N N 186 
A1AVC C17 H17  sing N N 187 
A1AVC C18 H18  sing N N 188 
A1AVC C18 H19  sing N N 189 
A1AVC C19 H20  sing N N 190 
A1AVC C20 H21  sing N N 191 
A1AVC C20 H22  sing N N 192 
A1AVC C20 H23  sing N N 193 
A1AVC C21 H24  sing N N 194 
A1AVC C21 H25  sing N N 195 
A1AVC C22 H26  sing N N 196 
A1AVC C22 H27  sing N N 197 
A1AVC C23 H28  sing N N 198 
A1AVC C23 H29  sing N N 199 
A1AVC C24 H30  sing N N 200 
A1AVC C25 H31  sing N N 201 
A1AVC C25 H32  sing N N 202 
A1AVC C25 H33  sing N N 203 
A1AVC C26 H34  sing N N 204 
A1AVC C26 H35  sing N N 205 
A1AVC C27 H36  sing N N 206 
A1AVC C27 H37  sing N N 207 
A1AVC C28 H38  sing N N 208 
A1AVC C28 H39  sing N N 209 
A1AVC C29 H40  sing N N 210 
A1AVC C30 H41  sing N N 211 
A1AVC C30 H42  sing N N 212 
A1AVC C30 H43  sing N N 213 
A1AVC C31 H44  sing N N 214 
A1AVC C31 H45  sing N N 215 
A1AVC C31 H46  sing N N 216 
A1AVC O32 H47  sing N N 217 
A1AVC O33 H48  sing N N 218 
ALA   N   CA   sing N N 219 
ALA   N   H    sing N N 220 
ALA   N   H2   sing N N 221 
ALA   CA  C    sing N N 222 
ALA   CA  CB   sing N N 223 
ALA   CA  HA   sing N N 224 
ALA   C   O    doub N N 225 
ALA   C   OXT  sing N N 226 
ALA   CB  HB1  sing N N 227 
ALA   CB  HB2  sing N N 228 
ALA   CB  HB3  sing N N 229 
ALA   OXT HXT  sing N N 230 
ARG   N   CA   sing N N 231 
ARG   N   H    sing N N 232 
ARG   N   H2   sing N N 233 
ARG   CA  C    sing N N 234 
ARG   CA  CB   sing N N 235 
ARG   CA  HA   sing N N 236 
ARG   C   O    doub N N 237 
ARG   C   OXT  sing N N 238 
ARG   CB  CG   sing N N 239 
ARG   CB  HB2  sing N N 240 
ARG   CB  HB3  sing N N 241 
ARG   CG  CD   sing N N 242 
ARG   CG  HG2  sing N N 243 
ARG   CG  HG3  sing N N 244 
ARG   CD  NE   sing N N 245 
ARG   CD  HD2  sing N N 246 
ARG   CD  HD3  sing N N 247 
ARG   NE  CZ   sing N N 248 
ARG   NE  HE   sing N N 249 
ARG   CZ  NH1  sing N N 250 
ARG   CZ  NH2  doub N N 251 
ARG   NH1 HH11 sing N N 252 
ARG   NH1 HH12 sing N N 253 
ARG   NH2 HH21 sing N N 254 
ARG   NH2 HH22 sing N N 255 
ARG   OXT HXT  sing N N 256 
ASN   N   CA   sing N N 257 
ASN   N   H    sing N N 258 
ASN   N   H2   sing N N 259 
ASN   CA  C    sing N N 260 
ASN   CA  CB   sing N N 261 
ASN   CA  HA   sing N N 262 
ASN   C   O    doub N N 263 
ASN   C   OXT  sing N N 264 
ASN   CB  CG   sing N N 265 
ASN   CB  HB2  sing N N 266 
ASN   CB  HB3  sing N N 267 
ASN   CG  OD1  doub N N 268 
ASN   CG  ND2  sing N N 269 
ASN   ND2 HD21 sing N N 270 
ASN   ND2 HD22 sing N N 271 
ASN   OXT HXT  sing N N 272 
ASP   N   CA   sing N N 273 
ASP   N   H    sing N N 274 
ASP   N   H2   sing N N 275 
ASP   CA  C    sing N N 276 
ASP   CA  CB   sing N N 277 
ASP   CA  HA   sing N N 278 
ASP   C   O    doub N N 279 
ASP   C   OXT  sing N N 280 
ASP   CB  CG   sing N N 281 
ASP   CB  HB2  sing N N 282 
ASP   CB  HB3  sing N N 283 
ASP   CG  OD1  doub N N 284 
ASP   CG  OD2  sing N N 285 
ASP   OD2 HD2  sing N N 286 
ASP   OXT HXT  sing N N 287 
CYS   N   CA   sing N N 288 
CYS   N   H    sing N N 289 
CYS   N   H2   sing N N 290 
CYS   CA  C    sing N N 291 
CYS   CA  CB   sing N N 292 
CYS   CA  HA   sing N N 293 
CYS   C   O    doub N N 294 
CYS   C   OXT  sing N N 295 
CYS   CB  SG   sing N N 296 
CYS   CB  HB2  sing N N 297 
CYS   CB  HB3  sing N N 298 
CYS   SG  HG   sing N N 299 
CYS   OXT HXT  sing N N 300 
GLN   N   CA   sing N N 301 
GLN   N   H    sing N N 302 
GLN   N   H2   sing N N 303 
GLN   CA  C    sing N N 304 
GLN   CA  CB   sing N N 305 
GLN   CA  HA   sing N N 306 
GLN   C   O    doub N N 307 
GLN   C   OXT  sing N N 308 
GLN   CB  CG   sing N N 309 
GLN   CB  HB2  sing N N 310 
GLN   CB  HB3  sing N N 311 
GLN   CG  CD   sing N N 312 
GLN   CG  HG2  sing N N 313 
GLN   CG  HG3  sing N N 314 
GLN   CD  OE1  doub N N 315 
GLN   CD  NE2  sing N N 316 
GLN   NE2 HE21 sing N N 317 
GLN   NE2 HE22 sing N N 318 
GLN   OXT HXT  sing N N 319 
GLU   N   CA   sing N N 320 
GLU   N   H    sing N N 321 
GLU   N   H2   sing N N 322 
GLU   CA  C    sing N N 323 
GLU   CA  CB   sing N N 324 
GLU   CA  HA   sing N N 325 
GLU   C   O    doub N N 326 
GLU   C   OXT  sing N N 327 
GLU   CB  CG   sing N N 328 
GLU   CB  HB2  sing N N 329 
GLU   CB  HB3  sing N N 330 
GLU   CG  CD   sing N N 331 
GLU   CG  HG2  sing N N 332 
GLU   CG  HG3  sing N N 333 
GLU   CD  OE1  doub N N 334 
GLU   CD  OE2  sing N N 335 
GLU   OE2 HE2  sing N N 336 
GLU   OXT HXT  sing N N 337 
GLY   N   CA   sing N N 338 
GLY   N   H    sing N N 339 
GLY   N   H2   sing N N 340 
GLY   CA  C    sing N N 341 
GLY   CA  HA2  sing N N 342 
GLY   CA  HA3  sing N N 343 
GLY   C   O    doub N N 344 
GLY   C   OXT  sing N N 345 
GLY   OXT HXT  sing N N 346 
HIS   N   CA   sing N N 347 
HIS   N   H    sing N N 348 
HIS   N   H2   sing N N 349 
HIS   CA  C    sing N N 350 
HIS   CA  CB   sing N N 351 
HIS   CA  HA   sing N N 352 
HIS   C   O    doub N N 353 
HIS   C   OXT  sing N N 354 
HIS   CB  CG   sing N N 355 
HIS   CB  HB2  sing N N 356 
HIS   CB  HB3  sing N N 357 
HIS   CG  ND1  sing Y N 358 
HIS   CG  CD2  doub Y N 359 
HIS   ND1 CE1  doub Y N 360 
HIS   ND1 HD1  sing N N 361 
HIS   CD2 NE2  sing Y N 362 
HIS   CD2 HD2  sing N N 363 
HIS   CE1 NE2  sing Y N 364 
HIS   CE1 HE1  sing N N 365 
HIS   NE2 HE2  sing N N 366 
HIS   OXT HXT  sing N N 367 
ILE   N   CA   sing N N 368 
ILE   N   H    sing N N 369 
ILE   N   H2   sing N N 370 
ILE   CA  C    sing N N 371 
ILE   CA  CB   sing N N 372 
ILE   CA  HA   sing N N 373 
ILE   C   O    doub N N 374 
ILE   C   OXT  sing N N 375 
ILE   CB  CG1  sing N N 376 
ILE   CB  CG2  sing N N 377 
ILE   CB  HB   sing N N 378 
ILE   CG1 CD1  sing N N 379 
ILE   CG1 HG12 sing N N 380 
ILE   CG1 HG13 sing N N 381 
ILE   CG2 HG21 sing N N 382 
ILE   CG2 HG22 sing N N 383 
ILE   CG2 HG23 sing N N 384 
ILE   CD1 HD11 sing N N 385 
ILE   CD1 HD12 sing N N 386 
ILE   CD1 HD13 sing N N 387 
ILE   OXT HXT  sing N N 388 
LEU   N   CA   sing N N 389 
LEU   N   H    sing N N 390 
LEU   N   H2   sing N N 391 
LEU   CA  C    sing N N 392 
LEU   CA  CB   sing N N 393 
LEU   CA  HA   sing N N 394 
LEU   C   O    doub N N 395 
LEU   C   OXT  sing N N 396 
LEU   CB  CG   sing N N 397 
LEU   CB  HB2  sing N N 398 
LEU   CB  HB3  sing N N 399 
LEU   CG  CD1  sing N N 400 
LEU   CG  CD2  sing N N 401 
LEU   CG  HG   sing N N 402 
LEU   CD1 HD11 sing N N 403 
LEU   CD1 HD12 sing N N 404 
LEU   CD1 HD13 sing N N 405 
LEU   CD2 HD21 sing N N 406 
LEU   CD2 HD22 sing N N 407 
LEU   CD2 HD23 sing N N 408 
LEU   OXT HXT  sing N N 409 
LYS   N   CA   sing N N 410 
LYS   N   H    sing N N 411 
LYS   N   H2   sing N N 412 
LYS   CA  C    sing N N 413 
LYS   CA  CB   sing N N 414 
LYS   CA  HA   sing N N 415 
LYS   C   O    doub N N 416 
LYS   C   OXT  sing N N 417 
LYS   CB  CG   sing N N 418 
LYS   CB  HB2  sing N N 419 
LYS   CB  HB3  sing N N 420 
LYS   CG  CD   sing N N 421 
LYS   CG  HG2  sing N N 422 
LYS   CG  HG3  sing N N 423 
LYS   CD  CE   sing N N 424 
LYS   CD  HD2  sing N N 425 
LYS   CD  HD3  sing N N 426 
LYS   CE  NZ   sing N N 427 
LYS   CE  HE2  sing N N 428 
LYS   CE  HE3  sing N N 429 
LYS   NZ  HZ1  sing N N 430 
LYS   NZ  HZ2  sing N N 431 
LYS   NZ  HZ3  sing N N 432 
LYS   OXT HXT  sing N N 433 
MET   N   CA   sing N N 434 
MET   N   H    sing N N 435 
MET   N   H2   sing N N 436 
MET   CA  C    sing N N 437 
MET   CA  CB   sing N N 438 
MET   CA  HA   sing N N 439 
MET   C   O    doub N N 440 
MET   C   OXT  sing N N 441 
MET   CB  CG   sing N N 442 
MET   CB  HB2  sing N N 443 
MET   CB  HB3  sing N N 444 
MET   CG  SD   sing N N 445 
MET   CG  HG2  sing N N 446 
MET   CG  HG3  sing N N 447 
MET   SD  CE   sing N N 448 
MET   CE  HE1  sing N N 449 
MET   CE  HE2  sing N N 450 
MET   CE  HE3  sing N N 451 
MET   OXT HXT  sing N N 452 
NAG   C1  C2   sing N N 453 
NAG   C1  O1   sing N N 454 
NAG   C1  O5   sing N N 455 
NAG   C1  H1   sing N N 456 
NAG   C2  C3   sing N N 457 
NAG   C2  N2   sing N N 458 
NAG   C2  H2   sing N N 459 
NAG   C3  C4   sing N N 460 
NAG   C3  O3   sing N N 461 
NAG   C3  H3   sing N N 462 
NAG   C4  C5   sing N N 463 
NAG   C4  O4   sing N N 464 
NAG   C4  H4   sing N N 465 
NAG   C5  C6   sing N N 466 
NAG   C5  O5   sing N N 467 
NAG   C5  H5   sing N N 468 
NAG   C6  O6   sing N N 469 
NAG   C6  H61  sing N N 470 
NAG   C6  H62  sing N N 471 
NAG   C7  C8   sing N N 472 
NAG   C7  N2   sing N N 473 
NAG   C7  O7   doub N N 474 
NAG   C8  H81  sing N N 475 
NAG   C8  H82  sing N N 476 
NAG   C8  H83  sing N N 477 
NAG   N2  HN2  sing N N 478 
NAG   O1  HO1  sing N N 479 
NAG   O3  HO3  sing N N 480 
NAG   O4  HO4  sing N N 481 
NAG   O6  HO6  sing N N 482 
PHE   N   CA   sing N N 483 
PHE   N   H    sing N N 484 
PHE   N   H2   sing N N 485 
PHE   CA  C    sing N N 486 
PHE   CA  CB   sing N N 487 
PHE   CA  HA   sing N N 488 
PHE   C   O    doub N N 489 
PHE   C   OXT  sing N N 490 
PHE   CB  CG   sing N N 491 
PHE   CB  HB2  sing N N 492 
PHE   CB  HB3  sing N N 493 
PHE   CG  CD1  doub Y N 494 
PHE   CG  CD2  sing Y N 495 
PHE   CD1 CE1  sing Y N 496 
PHE   CD1 HD1  sing N N 497 
PHE   CD2 CE2  doub Y N 498 
PHE   CD2 HD2  sing N N 499 
PHE   CE1 CZ   doub Y N 500 
PHE   CE1 HE1  sing N N 501 
PHE   CE2 CZ   sing Y N 502 
PHE   CE2 HE2  sing N N 503 
PHE   CZ  HZ   sing N N 504 
PHE   OXT HXT  sing N N 505 
PRO   N   CA   sing N N 506 
PRO   N   CD   sing N N 507 
PRO   N   H    sing N N 508 
PRO   CA  C    sing N N 509 
PRO   CA  CB   sing N N 510 
PRO   CA  HA   sing N N 511 
PRO   C   O    doub N N 512 
PRO   C   OXT  sing N N 513 
PRO   CB  CG   sing N N 514 
PRO   CB  HB2  sing N N 515 
PRO   CB  HB3  sing N N 516 
PRO   CG  CD   sing N N 517 
PRO   CG  HG2  sing N N 518 
PRO   CG  HG3  sing N N 519 
PRO   CD  HD2  sing N N 520 
PRO   CD  HD3  sing N N 521 
PRO   OXT HXT  sing N N 522 
SER   N   CA   sing N N 523 
SER   N   H    sing N N 524 
SER   N   H2   sing N N 525 
SER   CA  C    sing N N 526 
SER   CA  CB   sing N N 527 
SER   CA  HA   sing N N 528 
SER   C   O    doub N N 529 
SER   C   OXT  sing N N 530 
SER   CB  OG   sing N N 531 
SER   CB  HB2  sing N N 532 
SER   CB  HB3  sing N N 533 
SER   OG  HG   sing N N 534 
SER   OXT HXT  sing N N 535 
THR   N   CA   sing N N 536 
THR   N   H    sing N N 537 
THR   N   H2   sing N N 538 
THR   CA  C    sing N N 539 
THR   CA  CB   sing N N 540 
THR   CA  HA   sing N N 541 
THR   C   O    doub N N 542 
THR   C   OXT  sing N N 543 
THR   CB  OG1  sing N N 544 
THR   CB  CG2  sing N N 545 
THR   CB  HB   sing N N 546 
THR   OG1 HG1  sing N N 547 
THR   CG2 HG21 sing N N 548 
THR   CG2 HG22 sing N N 549 
THR   CG2 HG23 sing N N 550 
THR   OXT HXT  sing N N 551 
TRP   N   CA   sing N N 552 
TRP   N   H    sing N N 553 
TRP   N   H2   sing N N 554 
TRP   CA  C    sing N N 555 
TRP   CA  CB   sing N N 556 
TRP   CA  HA   sing N N 557 
TRP   C   O    doub N N 558 
TRP   C   OXT  sing N N 559 
TRP   CB  CG   sing N N 560 
TRP   CB  HB2  sing N N 561 
TRP   CB  HB3  sing N N 562 
TRP   CG  CD1  doub Y N 563 
TRP   CG  CD2  sing Y N 564 
TRP   CD1 NE1  sing Y N 565 
TRP   CD1 HD1  sing N N 566 
TRP   CD2 CE2  doub Y N 567 
TRP   CD2 CE3  sing Y N 568 
TRP   NE1 CE2  sing Y N 569 
TRP   NE1 HE1  sing N N 570 
TRP   CE2 CZ2  sing Y N 571 
TRP   CE3 CZ3  doub Y N 572 
TRP   CE3 HE3  sing N N 573 
TRP   CZ2 CH2  doub Y N 574 
TRP   CZ2 HZ2  sing N N 575 
TRP   CZ3 CH2  sing Y N 576 
TRP   CZ3 HZ3  sing N N 577 
TRP   CH2 HH2  sing N N 578 
TRP   OXT HXT  sing N N 579 
TYR   N   CA   sing N N 580 
TYR   N   H    sing N N 581 
TYR   N   H2   sing N N 582 
TYR   CA  C    sing N N 583 
TYR   CA  CB   sing N N 584 
TYR   CA  HA   sing N N 585 
TYR   C   O    doub N N 586 
TYR   C   OXT  sing N N 587 
TYR   CB  CG   sing N N 588 
TYR   CB  HB2  sing N N 589 
TYR   CB  HB3  sing N N 590 
TYR   CG  CD1  doub Y N 591 
TYR   CG  CD2  sing Y N 592 
TYR   CD1 CE1  sing Y N 593 
TYR   CD1 HD1  sing N N 594 
TYR   CD2 CE2  doub Y N 595 
TYR   CD2 HD2  sing N N 596 
TYR   CE1 CZ   doub Y N 597 
TYR   CE1 HE1  sing N N 598 
TYR   CE2 CZ   sing Y N 599 
TYR   CE2 HE2  sing N N 600 
TYR   CZ  OH   sing N N 601 
TYR   OH  HH   sing N N 602 
TYR   OXT HXT  sing N N 603 
VAL   N   CA   sing N N 604 
VAL   N   H    sing N N 605 
VAL   N   H2   sing N N 606 
VAL   CA  C    sing N N 607 
VAL   CA  CB   sing N N 608 
VAL   CA  HA   sing N N 609 
VAL   C   O    doub N N 610 
VAL   C   OXT  sing N N 611 
VAL   CB  CG1  sing N N 612 
VAL   CB  CG2  sing N N 613 
VAL   CB  HB   sing N N 614 
VAL   CG1 HG11 sing N N 615 
VAL   CG1 HG12 sing N N 616 
VAL   CG1 HG13 sing N N 617 
VAL   CG2 HG21 sing N N 618 
VAL   CG2 HG22 sing N N 619 
VAL   CG2 HG23 sing N N 620 
VAL   OXT HXT  sing N N 621 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-20 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9BVP 
_em_admin.last_update        2025-03-26 
_em_admin.map_release_date   2025-01-22 
_em_admin.title              
'Vitamin K-dependent gamma-carboxylase with TMG2 propeptide and glutamate-rich region and with vitamin K hydroquinone' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 150   mM NaCl       1 'Sodium chloride'        
1 20    mM C8H18N2O4S 2 HEPES                    
1 0.005 %  C56H92O25  3 Glyco-diosgenin          
1 0.055 mM C31H48O2   4 'Vitamin K hydroquinone' 
1 1.84  mM NaHCO3     5 'Sodium bicarbonate'     
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.1125 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 HEK293S 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              'pEG BacMam' 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     6226 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.21.1_5286: 
'IMAGE ACQUISITION'             ? 2  1 ? 1 ?      ?            
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?            
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?            
CLASSIFICATION                  ? 5  1 1 1 ?      ?            
MASKING                         ? 6  1 1 1 ?      ?            
RECONSTRUCTION                  ? 7  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?            
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?            
'CTF CORRECTION'                ? 10 1 1 1 ?      ?            
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?            
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?            
'MODEL FITTING'                 ? 13 1 1 1 ?      ?            
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?            
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?            
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?            
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?            
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?            
OTHER                           ? 19 1 1 1 ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)'             'United States' HL121718 1 
'American Heart Association'                                                                      'United States' 
'Established Investigator Award' 2 
'American Heart Association'                                                                      'United States' 
'Collaborative Sciences Award'   3 
'W. M. Keck Foundation'                                                                           'United States' 
'Forefront of Science Award'     4 
'Childrens Discovery Institute of Washington University and St. Louis Childrens Hospital'         'United States' 'MCII 2020-854' 
5 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' AI158500 6 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)'        'United States' GM131008 7 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
3 NAG 1 n 
3 NAG 2 n 
# 
_atom_sites.entry_id                    9BVP 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ASP   A 1 6   ? 146.212 171.695 157.807 1.00 112.50 ? 31  ASP   A N   1 
ATOM   2    C CA  . ASP   A 1 6   ? 145.783 173.023 157.389 1.00 118.91 ? 31  ASP   A CA  1 
ATOM   3    C C   . ASP   A 1 6   ? 146.141 173.271 155.928 1.00 111.80 ? 31  ASP   A C   1 
ATOM   4    O O   . ASP   A 1 6   ? 145.340 173.813 155.168 1.00 111.85 ? 31  ASP   A O   1 
ATOM   5    C CB  . ASP   A 1 6   ? 146.420 174.095 158.276 1.00 127.63 ? 31  ASP   A CB  1 
ATOM   6    C CG  . ASP   A 1 6   ? 146.026 173.955 159.734 1.00 133.43 ? 31  ASP   A CG  1 
ATOM   7    O OD1 . ASP   A 1 6   ? 144.908 173.469 160.007 1.00 136.72 ? 31  ASP   A OD1 1 
ATOM   8    O OD2 . ASP   A 1 6   ? 146.835 174.331 160.609 1.00 133.88 ? 31  ASP   A OD2 1 
ATOM   9    N N   . SER   A 1 7   ? 147.351 172.875 155.545 1.00 108.87 ? 32  SER   A N   1 
ATOM   10   C CA  . SER   A 1 7   ? 147.783 173.024 154.163 1.00 105.86 ? 32  SER   A CA  1 
ATOM   11   C C   . SER   A 1 7   ? 146.911 172.180 153.242 1.00 102.33 ? 32  SER   A C   1 
ATOM   12   O O   . SER   A 1 7   ? 146.449 171.096 153.607 1.00 104.25 ? 32  SER   A O   1 
ATOM   13   C CB  . SER   A 1 7   ? 149.248 172.616 154.018 1.00 107.48 ? 32  SER   A CB  1 
ATOM   14   O OG  . SER   A 1 7   ? 150.080 173.402 154.853 1.00 112.05 ? 32  SER   A OG  1 
ATOM   15   N N   . ARG   A 1 8   ? 146.677 172.698 152.034 1.00 102.27 ? 33  ARG   A N   1 
ATOM   16   C CA  . ARG   A 1 8   ? 145.825 171.993 151.082 1.00 105.73 ? 33  ARG   A CA  1 
ATOM   17   C C   . ARG   A 1 8   ? 146.424 170.648 150.694 1.00 103.73 ? 33  ARG   A C   1 
ATOM   18   O O   . ARG   A 1 8   ? 145.696 169.660 150.532 1.00 102.64 ? 33  ARG   A O   1 
ATOM   19   C CB  . ARG   A 1 8   ? 145.593 172.856 149.844 1.00 109.54 ? 33  ARG   A CB  1 
ATOM   20   C CG  . ARG   A 1 8   ? 144.666 174.034 150.085 1.00 113.02 ? 33  ARG   A CG  1 
ATOM   21   C CD  . ARG   A 1 8   ? 144.306 174.738 148.788 1.00 115.41 ? 33  ARG   A CD  1 
ATOM   22   N NE  . ARG   A 1 8   ? 143.322 175.795 148.993 1.00 120.10 ? 33  ARG   A NE  1 
ATOM   23   C CZ  . ARG   A 1 8   ? 142.780 176.527 148.028 1.00 122.93 ? 33  ARG   A CZ  1 
ATOM   24   N NH1 . ARG   A 1 8   ? 143.102 176.351 146.755 1.00 122.87 ? 33  ARG   A NH1 1 
ATOM   25   N NH2 . ARG   A 1 8   ? 141.890 177.463 148.347 1.00 123.30 ? 33  ARG   A NH2 1 
ATOM   26   N N   . ILE   A 1 9   ? 147.747 170.589 150.532 1.00 102.45 ? 34  ILE   A N   1 
ATOM   27   C CA  . ILE   A 1 9   ? 148.397 169.317 150.230 1.00 99.39  ? 34  ILE   A CA  1 
ATOM   28   C C   . ILE   A 1 9   ? 148.194 168.344 151.382 1.00 94.24  ? 34  ILE   A C   1 
ATOM   29   O O   . ILE   A 1 9   ? 147.963 167.148 151.170 1.00 95.43  ? 34  ILE   A O   1 
ATOM   30   C CB  . ILE   A 1 9   ? 149.893 169.531 149.914 1.00 102.81 ? 34  ILE   A CB  1 
ATOM   31   C CG1 . ILE   A 1 9   ? 150.079 170.099 148.495 1.00 106.17 ? 34  ILE   A CG1 1 
ATOM   32   C CG2 . ILE   A 1 9   ? 150.681 168.216 150.054 1.00 100.17 ? 34  ILE   A CG2 1 
ATOM   33   C CD1 . ILE   A 1 9   ? 149.625 171.534 148.312 1.00 104.82 ? 34  ILE   A CD1 1 
ATOM   34   N N   . GLY   A 1 10  ? 148.291 168.835 152.616 1.00 91.01  ? 35  GLY   A N   1 
ATOM   35   C CA  . GLY   A 1 10  ? 148.048 167.976 153.762 1.00 92.88  ? 35  GLY   A CA  1 
ATOM   36   C C   . GLY   A 1 10  ? 146.638 167.422 153.787 1.00 90.79  ? 35  GLY   A C   1 
ATOM   37   O O   . GLY   A 1 10  ? 146.429 166.242 154.078 1.00 92.41  ? 35  GLY   A O   1 
ATOM   38   N N   . LYS   A 1 11  ? 145.650 168.266 153.489 1.00 88.21  ? 36  LYS   A N   1 
ATOM   39   C CA  . LYS   A 1 11  ? 144.268 167.804 153.474 1.00 86.36  ? 36  LYS   A CA  1 
ATOM   40   C C   . LYS   A 1 11  ? 144.037 166.786 152.365 1.00 89.02  ? 36  LYS   A C   1 
ATOM   41   O O   . LYS   A 1 11  ? 143.394 165.753 152.588 1.00 90.91  ? 36  LYS   A O   1 
ATOM   42   C CB  . LYS   A 1 11  ? 143.322 168.992 153.317 1.00 95.46  ? 36  LYS   A CB  1 
ATOM   43   C CG  . LYS   A 1 11  ? 141.850 168.651 153.520 1.00 101.67 ? 36  LYS   A CG  1 
ATOM   44   C CD  . LYS   A 1 11  ? 140.941 169.873 153.372 1.00 106.75 ? 36  LYS   A CD  1 
ATOM   45   C CE  . LYS   A 1 11  ? 141.095 170.879 154.512 1.00 106.59 ? 36  LYS   A CE  1 
ATOM   46   N NZ  . LYS   A 1 11  ? 140.831 170.288 155.855 1.00 104.74 ? 36  LYS   A NZ  1 
ATOM   47   N N   . LEU   A 1 12  ? 144.545 167.059 151.162 1.00 89.67  ? 37  LEU   A N   1 
ATOM   48   C CA  . LEU   A 1 12  ? 144.304 166.156 150.041 1.00 87.97  ? 37  LEU   A CA  1 
ATOM   49   C C   . LEU   A 1 12  ? 145.020 164.825 150.234 1.00 82.37  ? 37  LEU   A C   1 
ATOM   50   O O   . LEU   A 1 12  ? 144.407 163.759 150.110 1.00 84.00  ? 37  LEU   A O   1 
ATOM   51   C CB  . LEU   A 1 12  ? 144.746 166.813 148.733 1.00 89.28  ? 37  LEU   A CB  1 
ATOM   52   C CG  . LEU   A 1 12  ? 143.945 168.024 148.250 1.00 93.58  ? 37  LEU   A CG  1 
ATOM   53   C CD1 . LEU   A 1 12  ? 144.596 168.622 147.013 1.00 93.25  ? 37  LEU   A CD1 1 
ATOM   54   C CD2 . LEU   A 1 12  ? 142.498 167.654 147.962 1.00 92.23  ? 37  LEU   A CD2 1 
ATOM   55   N N   . LEU   A 1 13  ? 146.315 164.863 150.532 1.00 76.75  ? 38  LEU   A N   1 
ATOM   56   C CA  . LEU   A 1 13  ? 147.117 163.654 150.646 1.00 78.33  ? 38  LEU   A CA  1 
ATOM   57   C C   . LEU   A 1 13  ? 147.098 163.043 152.041 1.00 80.94  ? 38  LEU   A C   1 
ATOM   58   O O   . LEU   A 1 13  ? 147.526 161.895 152.200 1.00 84.22  ? 38  LEU   A O   1 
ATOM   59   C CB  . LEU   A 1 13  ? 148.567 163.946 150.247 1.00 84.90  ? 38  LEU   A CB  1 
ATOM   60   C CG  . LEU   A 1 13  ? 148.861 164.095 148.752 1.00 86.47  ? 38  LEU   A CG  1 
ATOM   61   C CD1 . LEU   A 1 13  ? 148.268 165.374 148.180 1.00 89.91  ? 38  LEU   A CD1 1 
ATOM   62   C CD2 . LEU   A 1 13  ? 150.360 164.042 148.507 1.00 87.70  ? 38  LEU   A CD2 1 
ATOM   63   N N   . GLY   A 1 14  ? 146.624 163.769 153.050 1.00 81.93  ? 39  GLY   A N   1 
ATOM   64   C CA  . GLY   A 1 14  ? 146.543 163.247 154.396 1.00 78.43  ? 39  GLY   A CA  1 
ATOM   65   C C   . GLY   A 1 14  ? 147.813 163.338 155.213 1.00 77.41  ? 39  GLY   A C   1 
ATOM   66   O O   . GLY   A 1 14  ? 147.803 162.919 156.377 1.00 80.22  ? 39  GLY   A O   1 
ATOM   67   N N   . PHE   A 1 15  ? 148.904 163.857 154.653 1.00 79.51  ? 40  PHE   A N   1 
ATOM   68   C CA  . PHE   A 1 15  ? 150.142 164.023 155.401 1.00 82.54  ? 40  PHE   A CA  1 
ATOM   69   C C   . PHE   A 1 15  ? 150.851 165.280 154.924 1.00 91.63  ? 40  PHE   A C   1 
ATOM   70   O O   . PHE   A 1 15  ? 150.676 165.723 153.785 1.00 93.96  ? 40  PHE   A O   1 
ATOM   71   C CB  . PHE   A 1 15  ? 151.060 162.805 155.251 1.00 81.68  ? 40  PHE   A CB  1 
ATOM   72   C CG  . PHE   A 1 15  ? 151.572 162.594 153.856 1.00 82.53  ? 40  PHE   A CG  1 
ATOM   73   C CD1 . PHE   A 1 15  ? 150.825 161.895 152.931 1.00 81.32  ? 40  PHE   A CD1 1 
ATOM   74   C CD2 . PHE   A 1 15  ? 152.809 163.082 153.475 1.00 87.40  ? 40  PHE   A CD2 1 
ATOM   75   C CE1 . PHE   A 1 15  ? 151.293 161.696 151.653 1.00 83.44  ? 40  PHE   A CE1 1 
ATOM   76   C CE2 . PHE   A 1 15  ? 153.280 162.888 152.198 1.00 90.18  ? 40  PHE   A CE2 1 
ATOM   77   C CZ  . PHE   A 1 15  ? 152.522 162.192 151.285 1.00 87.74  ? 40  PHE   A CZ  1 
ATOM   78   N N   . GLU   A 1 16  ? 151.669 165.840 155.807 1.00 91.79  ? 41  GLU   A N   1 
ATOM   79   C CA  . GLU   A 1 16  ? 152.451 167.027 155.501 1.00 92.14  ? 41  GLU   A CA  1 
ATOM   80   C C   . GLU   A 1 16  ? 153.815 166.632 154.944 1.00 94.21  ? 41  GLU   A C   1 
ATOM   81   O O   . GLU   A 1 16  ? 154.297 165.515 155.143 1.00 96.61  ? 41  GLU   A O   1 
ATOM   82   C CB  . GLU   A 1 16  ? 152.628 167.895 156.748 1.00 92.30  ? 41  GLU   A CB  1 
ATOM   83   C CG  . GLU   A 1 16  ? 151.330 168.269 157.451 1.00 95.99  ? 41  GLU   A CG  1 
ATOM   84   C CD  . GLU   A 1 16  ? 150.409 169.099 156.582 1.00 104.46 ? 41  GLU   A CD  1 
ATOM   85   O OE1 . GLU   A 1 16  ? 150.890 169.681 155.587 1.00 108.54 ? 41  GLU   A OE1 1 
ATOM   86   O OE2 . GLU   A 1 16  ? 149.202 169.171 156.895 1.00 102.98 ? 41  GLU   A OE2 1 
ATOM   87   N N   . TRP   A 1 17  ? 154.435 167.573 154.229 1.00 94.15  ? 42  TRP   A N   1 
ATOM   88   C CA  . TRP   A 1 17  ? 155.760 167.322 153.671 1.00 95.27  ? 42  TRP   A CA  1 
ATOM   89   C C   . TRP   A 1 17  ? 156.787 167.096 154.770 1.00 95.19  ? 42  TRP   A C   1 
ATOM   90   O O   . TRP   A 1 17  ? 157.636 166.202 154.664 1.00 98.85  ? 42  TRP   A O   1 
ATOM   91   C CB  . TRP   A 1 17  ? 156.185 168.486 152.778 1.00 97.02  ? 42  TRP   A CB  1 
ATOM   92   C CG  . TRP   A 1 17  ? 155.345 168.640 151.554 1.00 99.97  ? 42  TRP   A CG  1 
ATOM   93   C CD1 . TRP   A 1 17  ? 154.472 169.650 151.283 1.00 99.15  ? 42  TRP   A CD1 1 
ATOM   94   C CD2 . TRP   A 1 17  ? 155.293 167.753 150.432 1.00 105.92 ? 42  TRP   A CD2 1 
ATOM   95   N NE1 . TRP   A 1 17  ? 153.882 169.450 150.061 1.00 103.42 ? 42  TRP   A NE1 1 
ATOM   96   C CE2 . TRP   A 1 17  ? 154.369 168.291 149.518 1.00 107.97 ? 42  TRP   A CE2 1 
ATOM   97   C CE3 . TRP   A 1 17  ? 155.940 166.555 150.112 1.00 106.31 ? 42  TRP   A CE3 1 
ATOM   98   C CZ2 . TRP   A 1 17  ? 154.073 167.674 148.304 1.00 110.77 ? 42  TRP   A CZ2 1 
ATOM   99   C CZ3 . TRP   A 1 17  ? 155.646 165.944 148.906 1.00 109.68 ? 42  TRP   A CZ3 1 
ATOM   100  C CH2 . TRP   A 1 17  ? 154.721 166.505 148.018 1.00 110.94 ? 42  TRP   A CH2 1 
ATOM   101  N N   . THR   A 1 18  ? 156.713 167.885 155.845 1.00 92.18  ? 43  THR   A N   1 
ATOM   102  C CA  . THR   A 1 18  ? 157.677 167.763 156.934 1.00 97.74  ? 43  THR   A CA  1 
ATOM   103  C C   . THR   A 1 18  ? 157.643 166.390 157.592 1.00 97.01  ? 43  THR   A C   1 
ATOM   104  O O   . THR   A 1 18  ? 158.623 166.002 158.237 1.00 96.46  ? 43  THR   A O   1 
ATOM   105  C CB  . THR   A 1 18  ? 157.429 168.848 157.989 1.00 103.37 ? 43  THR   A CB  1 
ATOM   106  O OG1 . THR   A 1 18  ? 158.458 168.791 158.985 1.00 104.64 ? 43  THR   A OG1 1 
ATOM   107  C CG2 . THR   A 1 18  ? 156.066 168.673 158.666 1.00 99.96  ? 43  THR   A CG2 1 
ATOM   108  N N   . ASP   A 1 19  ? 156.544 165.647 157.450 1.00 94.40  ? 44  ASP   A N   1 
ATOM   109  C CA  . ASP   A 1 19  ? 156.486 164.294 157.987 1.00 91.07  ? 44  ASP   A CA  1 
ATOM   110  C C   . ASP   A 1 19  ? 157.491 163.360 157.326 1.00 91.78  ? 44  ASP   A C   1 
ATOM   111  O O   . ASP   A 1 19  ? 157.848 162.340 157.925 1.00 94.32  ? 44  ASP   A O   1 
ATOM   112  C CB  . ASP   A 1 19  ? 155.076 163.727 157.824 1.00 93.77  ? 44  ASP   A CB  1 
ATOM   113  C CG  . ASP   A 1 19  ? 154.026 164.573 158.515 1.00 102.98 ? 44  ASP   A CG  1 
ATOM   114  O OD1 . ASP   A 1 19  ? 154.357 165.224 159.527 1.00 100.64 ? 44  ASP   A OD1 1 
ATOM   115  O OD2 . ASP   A 1 19  ? 152.869 164.586 158.045 1.00 104.31 ? 44  ASP   A OD2 1 
ATOM   116  N N   . LEU   A 1 20  ? 157.959 163.681 156.118 1.00 91.26  ? 45  LEU   A N   1 
ATOM   117  C CA  . LEU   A 1 20  ? 158.910 162.847 155.395 1.00 89.13  ? 45  LEU   A CA  1 
ATOM   118  C C   . LEU   A 1 20  ? 160.344 163.357 155.490 1.00 89.35  ? 45  LEU   A C   1 
ATOM   119  O O   . LEU   A 1 20  ? 161.212 162.861 154.766 1.00 90.26  ? 45  LEU   A O   1 
ATOM   120  C CB  . LEU   A 1 20  ? 158.503 162.743 153.925 1.00 85.89  ? 45  LEU   A CB  1 
ATOM   121  C CG  . LEU   A 1 20  ? 157.129 162.147 153.623 1.00 87.87  ? 45  LEU   A CG  1 
ATOM   122  C CD1 . LEU   A 1 20  ? 156.849 162.226 152.132 1.00 91.20  ? 45  LEU   A CD1 1 
ATOM   123  C CD2 . LEU   A 1 20  ? 157.027 160.713 154.105 1.00 90.26  ? 45  LEU   A CD2 1 
ATOM   124  N N   . SER   A 1 21  ? 160.615 164.334 156.359 1.00 91.19  ? 46  SER   A N   1 
ATOM   125  C CA  . SER   A 1 21  ? 161.967 164.877 156.452 1.00 91.18  ? 46  SER   A CA  1 
ATOM   126  C C   . SER   A 1 21  ? 162.952 163.839 156.976 1.00 89.23  ? 46  SER   A C   1 
ATOM   127  O O   . SER   A 1 21  ? 164.084 163.752 156.487 1.00 92.04  ? 46  SER   A O   1 
ATOM   128  C CB  . SER   A 1 21  ? 161.974 166.121 157.339 1.00 94.27  ? 46  SER   A CB  1 
ATOM   129  O OG  . SER   A 1 21  ? 161.624 165.805 158.672 1.00 99.39  ? 46  SER   A OG  1 
ATOM   130  N N   . SER   A 1 22  ? 162.544 163.048 157.968 1.00 87.72  ? 47  SER   A N   1 
ATOM   131  C CA  . SER   A 1 22  ? 163.419 162.088 158.627 1.00 88.41  ? 47  SER   A CA  1 
ATOM   132  C C   . SER   A 1 22  ? 162.725 160.738 158.743 1.00 90.35  ? 47  SER   A C   1 
ATOM   133  O O   . SER   A 1 22  ? 161.508 160.619 158.580 1.00 93.18  ? 47  SER   A O   1 
ATOM   134  C CB  . SER   A 1 22  ? 163.834 162.576 160.019 1.00 90.53  ? 47  SER   A CB  1 
ATOM   135  O OG  . SER   A 1 22  ? 164.672 161.629 160.658 1.00 91.89  ? 47  SER   A OG  1 
ATOM   136  N N   . TRP   A 1 23  ? 163.533 159.713 159.026 1.00 84.41  ? 48  TRP   A N   1 
ATOM   137  C CA  . TRP   A 1 23  ? 163.020 158.349 159.103 1.00 83.30  ? 48  TRP   A CA  1 
ATOM   138  C C   . TRP   A 1 23  ? 162.046 158.179 160.262 1.00 87.66  ? 48  TRP   A C   1 
ATOM   139  O O   . TRP   A 1 23  ? 161.023 157.495 160.127 1.00 89.52  ? 48  TRP   A O   1 
ATOM   140  C CB  . TRP   A 1 23  ? 164.185 157.371 159.235 1.00 80.34  ? 48  TRP   A CB  1 
ATOM   141  C CG  . TRP   A 1 23  ? 163.767 155.954 159.437 1.00 79.13  ? 48  TRP   A CG  1 
ATOM   142  C CD1 . TRP   A 1 23  ? 163.963 155.197 160.550 1.00 77.79  ? 48  TRP   A CD1 1 
ATOM   143  C CD2 . TRP   A 1 23  ? 163.081 155.121 158.498 1.00 82.42  ? 48  TRP   A CD2 1 
ATOM   144  N NE1 . TRP   A 1 23  ? 163.444 153.942 160.365 1.00 78.71  ? 48  TRP   A NE1 1 
ATOM   145  C CE2 . TRP   A 1 23  ? 162.896 153.870 159.112 1.00 78.31  ? 48  TRP   A CE2 1 
ATOM   146  C CE3 . TRP   A 1 23  ? 162.607 155.311 157.198 1.00 87.47  ? 48  TRP   A CE3 1 
ATOM   147  C CZ2 . TRP   A 1 23  ? 162.257 152.814 158.475 1.00 77.63  ? 48  TRP   A CZ2 1 
ATOM   148  C CZ3 . TRP   A 1 23  ? 161.973 154.260 156.567 1.00 83.72  ? 48  TRP   A CZ3 1 
ATOM   149  C CH2 . TRP   A 1 23  ? 161.804 153.028 157.205 1.00 79.08  ? 48  TRP   A CH2 1 
ATOM   150  N N   . ARG   A 1 24  ? 162.356 158.778 161.413 1.00 85.85  ? 49  ARG   A N   1 
ATOM   151  C CA  . ARG   A 1 24  ? 161.505 158.618 162.587 1.00 83.04  ? 49  ARG   A CA  1 
ATOM   152  C C   . ARG   A 1 24  ? 160.116 159.189 162.337 1.00 83.37  ? 49  ARG   A C   1 
ATOM   153  O O   . ARG   A 1 24  ? 159.105 158.589 162.726 1.00 87.50  ? 49  ARG   A O   1 
ATOM   154  C CB  . ARG   A 1 24  ? 162.162 159.290 163.792 1.00 83.85  ? 49  ARG   A CB  1 
ATOM   155  C CG  . ARG   A 1 24  ? 161.428 159.106 165.109 1.00 89.34  ? 49  ARG   A CG  1 
ATOM   156  C CD  . ARG   A 1 24  ? 162.231 159.691 166.258 1.00 93.33  ? 49  ARG   A CD  1 
ATOM   157  N NE  . ARG   A 1 24  ? 161.503 159.660 167.521 1.00 99.01  ? 49  ARG   A NE  1 
ATOM   158  C CZ  . ARG   A 1 24  ? 161.959 160.143 168.670 1.00 99.37  ? 49  ARG   A CZ  1 
ATOM   159  N NH1 . ARG   A 1 24  ? 163.153 160.709 168.764 1.00 99.23  ? 49  ARG   A NH1 1 
ATOM   160  N NH2 . ARG   A 1 24  ? 161.197 160.056 169.757 1.00 97.10  ? 49  ARG   A NH2 1 
ATOM   161  N N   . ARG   A 1 25  ? 160.047 160.345 161.679 1.00 79.83  ? 50  ARG   A N   1 
ATOM   162  C CA  . ARG   A 1 25  ? 158.752 160.929 161.356 1.00 82.73  ? 50  ARG   A CA  1 
ATOM   163  C C   . ARG   A 1 25  ? 157.988 160.056 160.370 1.00 82.21  ? 50  ARG   A C   1 
ATOM   164  O O   . ARG   A 1 25  ? 156.760 159.956 160.447 1.00 86.93  ? 50  ARG   A O   1 
ATOM   165  C CB  . ARG   A 1 25  ? 158.941 162.340 160.809 1.00 87.86  ? 50  ARG   A CB  1 
ATOM   166  C CG  . ARG   A 1 25  ? 159.595 163.292 161.802 1.00 90.64  ? 50  ARG   A CG  1 
ATOM   167  C CD  . ARG   A 1 25  ? 159.878 164.640 161.178 1.00 93.57  ? 50  ARG   A CD  1 
ATOM   168  N NE  . ARG   A 1 25  ? 160.709 165.475 162.038 1.00 101.04 ? 50  ARG   A NE  1 
ATOM   169  C CZ  . ARG   A 1 25  ? 161.132 166.696 161.735 1.00 104.80 ? 50  ARG   A CZ  1 
ATOM   170  N NH1 . ARG   A 1 25  ? 160.822 167.276 160.585 1.00 103.96 ? 50  ARG   A NH1 1 
ATOM   171  N NH2 . ARG   A 1 25  ? 161.888 167.354 162.609 1.00 102.41 ? 50  ARG   A NH2 1 
ATOM   172  N N   . LEU   A 1 26  ? 158.695 159.408 159.441 1.00 77.48  ? 51  LEU   A N   1 
ATOM   173  C CA  . LEU   A 1 26  ? 158.027 158.496 158.518 1.00 76.71  ? 51  LEU   A CA  1 
ATOM   174  C C   . LEU   A 1 26  ? 157.443 157.299 159.255 1.00 77.29  ? 51  LEU   A C   1 
ATOM   175  O O   . LEU   A 1 26  ? 156.320 156.867 158.962 1.00 81.31  ? 51  LEU   A O   1 
ATOM   176  C CB  . LEU   A 1 26  ? 159.000 158.040 157.432 1.00 79.14  ? 51  LEU   A CB  1 
ATOM   177  C CG  . LEU   A 1 26  ? 158.496 157.004 156.422 1.00 83.09  ? 51  LEU   A CG  1 
ATOM   178  C CD1 . LEU   A 1 26  ? 157.192 157.441 155.786 1.00 84.33  ? 51  LEU   A CD1 1 
ATOM   179  C CD2 . LEU   A 1 26  ? 159.543 156.760 155.355 1.00 84.55  ? 51  LEU   A CD2 1 
ATOM   180  N N   . VAL   A 1 27  ? 158.192 156.741 160.209 1.00 74.53  ? 52  VAL   A N   1 
ATOM   181  C CA  . VAL   A 1 27  ? 157.674 155.623 160.994 1.00 73.73  ? 52  VAL   A CA  1 
ATOM   182  C C   . VAL   A 1 27  ? 156.451 156.059 161.789 1.00 78.59  ? 52  VAL   A C   1 
ATOM   183  O O   . VAL   A 1 27  ? 155.446 155.338 161.864 1.00 81.49  ? 52  VAL   A O   1 
ATOM   184  C CB  . VAL   A 1 27  ? 158.774 155.055 161.909 1.00 74.97  ? 52  VAL   A CB  1 
ATOM   185  C CG1 . VAL   A 1 27  ? 158.202 154.018 162.857 1.00 77.12  ? 52  VAL   A CG1 1 
ATOM   186  C CG2 . VAL   A 1 27  ? 159.896 154.448 161.080 1.00 79.87  ? 52  VAL   A CG2 1 
ATOM   187  N N   . THR   A 1 28  ? 156.513 157.251 162.389 1.00 78.07  ? 53  THR   A N   1 
ATOM   188  C CA  . THR   A 1 28  ? 155.372 157.758 163.145 1.00 72.63  ? 53  THR   A CA  1 
ATOM   189  C C   . THR   A 1 28  ? 154.156 157.955 162.248 1.00 69.42  ? 53  THR   A C   1 
ATOM   190  O O   . THR   A 1 28  ? 153.027 157.647 162.645 1.00 76.66  ? 53  THR   A O   1 
ATOM   191  C CB  . THR   A 1 28  ? 155.744 159.070 163.836 1.00 76.07  ? 53  THR   A CB  1 
ATOM   192  O OG1 . THR   A 1 28  ? 156.824 158.845 164.748 1.00 78.03  ? 53  THR   A OG1 1 
ATOM   193  C CG2 . THR   A 1 28  ? 154.555 159.631 164.597 1.00 81.67  ? 53  THR   A CG2 1 
ATOM   194  N N   . LEU   A 1 29  ? 154.364 158.473 161.037 1.00 67.82  ? 54  LEU   A N   1 
ATOM   195  C CA  . LEU   A 1 29  ? 153.258 158.641 160.101 1.00 69.48  ? 54  LEU   A CA  1 
ATOM   196  C C   . LEU   A 1 29  ? 152.651 157.300 159.716 1.00 71.88  ? 54  LEU   A C   1 
ATOM   197  O O   . LEU   A 1 29  ? 151.424 157.152 159.687 1.00 73.84  ? 54  LEU   A O   1 
ATOM   198  C CB  . LEU   A 1 29  ? 153.738 159.387 158.856 1.00 73.10  ? 54  LEU   A CB  1 
ATOM   199  C CG  . LEU   A 1 29  ? 152.727 159.627 157.731 1.00 76.29  ? 54  LEU   A CG  1 
ATOM   200  C CD1 . LEU   A 1 29  ? 151.532 160.415 158.229 1.00 78.01  ? 54  LEU   A CD1 1 
ATOM   201  C CD2 . LEU   A 1 29  ? 153.396 160.350 156.580 1.00 83.11  ? 54  LEU   A CD2 1 
ATOM   202  N N   . LEU   A 1 30  ? 153.488 156.308 159.418 1.00 70.10  ? 55  LEU   A N   1 
ATOM   203  C CA  . LEU   A 1 30  ? 152.981 155.013 158.987 1.00 67.44  ? 55  LEU   A CA  1 
ATOM   204  C C   . LEU   A 1 30  ? 152.440 154.167 160.132 1.00 70.65  ? 55  LEU   A C   1 
ATOM   205  O O   . LEU   A 1 30  ? 151.837 153.122 159.861 1.00 76.48  ? 55  LEU   A O   1 
ATOM   206  C CB  . LEU   A 1 30  ? 154.073 154.229 158.255 1.00 68.96  ? 55  LEU   A CB  1 
ATOM   207  C CG  . LEU   A 1 30  ? 154.471 154.719 156.861 1.00 70.49  ? 55  LEU   A CG  1 
ATOM   208  C CD1 . LEU   A 1 30  ? 155.664 153.935 156.361 1.00 72.89  ? 55  LEU   A CD1 1 
ATOM   209  C CD2 . LEU   A 1 30  ? 153.322 154.608 155.879 1.00 72.27  ? 55  LEU   A CD2 1 
ATOM   210  N N   . ASN   A 1 31  ? 152.642 154.577 161.389 1.00 68.14  ? 56  ASN   A N   1 
ATOM   211  C CA  . ASN   A 1 31  ? 152.100 153.869 162.545 1.00 65.51  ? 56  ASN   A CA  1 
ATOM   212  C C   . ASN   A 1 31  ? 151.150 154.734 163.371 1.00 70.08  ? 56  ASN   A C   1 
ATOM   213  O O   . ASN   A 1 31  ? 150.947 154.464 164.558 1.00 76.94  ? 56  ASN   A O   1 
ATOM   214  C CB  . ASN   A 1 31  ? 153.241 153.344 163.414 1.00 67.75  ? 56  ASN   A CB  1 
ATOM   215  C CG  . ASN   A 1 31  ? 154.038 152.264 162.724 1.00 72.45  ? 56  ASN   A CG  1 
ATOM   216  O OD1 . ASN   A 1 31  ? 153.772 151.076 162.897 1.00 74.80  ? 56  ASN   A OD1 1 
ATOM   217  N ND2 . ASN   A 1 31  ? 155.017 152.668 161.927 1.00 75.76  ? 56  ASN   A ND2 1 
ATOM   218  N N   . ARG   A 1 32  ? 150.556 155.762 162.772 1.00 66.09  ? 57  ARG   A N   1 
ATOM   219  C CA  . ARG   A 1 32  ? 149.616 156.600 163.498 1.00 61.53  ? 57  ARG   A CA  1 
ATOM   220  C C   . ARG   A 1 32  ? 148.308 155.843 163.749 1.00 63.06  ? 57  ARG   A C   1 
ATOM   221  O O   . ARG   A 1 32  ? 147.997 154.882 163.041 1.00 67.64  ? 57  ARG   A O   1 
ATOM   222  C CB  . ARG   A 1 32  ? 149.332 157.885 162.727 1.00 62.41  ? 57  ARG   A CB  1 
ATOM   223  C CG  . ARG   A 1 32  ? 148.687 157.672 161.365 1.00 68.28  ? 57  ARG   A CG  1 
ATOM   224  C CD  . ARG   A 1 32  ? 148.685 158.941 160.526 1.00 70.44  ? 57  ARG   A CD  1 
ATOM   225  N NE  . ARG   A 1 32  ? 147.553 159.807 160.826 1.00 66.72  ? 57  ARG   A NE  1 
ATOM   226  C CZ  . ARG   A 1 32  ? 147.181 160.845 160.087 1.00 70.14  ? 57  ARG   A CZ  1 
ATOM   227  N NH1 . ARG   A 1 32  ? 147.828 161.180 158.981 1.00 68.77  ? 57  ARG   A NH1 1 
ATOM   228  N NH2 . ARG   A 1 32  ? 146.131 161.567 160.466 1.00 73.76  ? 57  ARG   A NH2 1 
ATOM   229  N N   . PRO   A 1 33  ? 147.527 156.246 164.755 1.00 57.70  ? 58  PRO   A N   1 
ATOM   230  C CA  . PRO   A 1 33  ? 146.247 155.569 164.997 1.00 60.00  ? 58  PRO   A CA  1 
ATOM   231  C C   . PRO   A 1 33  ? 145.262 155.757 163.854 1.00 65.88  ? 58  PRO   A C   1 
ATOM   232  O O   . PRO   A 1 33  ? 145.269 156.772 163.153 1.00 73.40  ? 58  PRO   A O   1 
ATOM   233  C CB  . PRO   A 1 33  ? 145.727 156.234 166.276 1.00 62.45  ? 58  PRO   A CB  1 
ATOM   234  C CG  . PRO   A 1 33  ? 146.900 156.848 166.901 1.00 61.72  ? 58  PRO   A CG  1 
ATOM   235  C CD  . PRO   A 1 33  ? 147.800 157.253 165.796 1.00 59.87  ? 58  PRO   A CD  1 
ATOM   236  N N   . THR   A 1 34  ? 144.403 154.756 163.676 1.00 60.98  ? 59  THR   A N   1 
ATOM   237  C CA  . THR   A 1 34  ? 143.323 154.811 162.700 1.00 58.00  ? 59  THR   A CA  1 
ATOM   238  C C   . THR   A 1 34  ? 142.227 153.856 163.156 1.00 62.56  ? 59  THR   A C   1 
ATOM   239  O O   . THR   A 1 34  ? 142.482 152.912 163.908 1.00 68.57  ? 59  THR   A O   1 
ATOM   240  C CB  . THR   A 1 34  ? 143.817 154.447 161.294 1.00 64.62  ? 59  THR   A CB  1 
ATOM   241  O OG1 . THR   A 1 34  ? 144.988 155.209 160.981 1.00 67.07  ? 59  THR   A OG1 1 
ATOM   242  C CG2 . THR   A 1 34  ? 142.755 154.735 160.243 1.00 67.60  ? 59  THR   A CG2 1 
ATOM   243  N N   . ASP   A 1 35  ? 141.004 154.110 162.697 1.00 61.72  ? 60  ASP   A N   1 
ATOM   244  C CA  . ASP   A 1 35  ? 139.889 153.256 163.073 1.00 62.25  ? 60  ASP   A CA  1 
ATOM   245  C C   . ASP   A 1 35  ? 140.009 151.891 162.388 1.00 64.45  ? 60  ASP   A C   1 
ATOM   246  O O   . ASP   A 1 35  ? 140.506 151.801 161.262 1.00 69.50  ? 60  ASP   A O   1 
ATOM   247  C CB  . ASP   A 1 35  ? 138.559 153.901 162.701 1.00 65.12  ? 60  ASP   A CB  1 
ATOM   248  C CG  . ASP   A 1 35  ? 137.997 154.755 163.814 1.00 75.69  ? 60  ASP   A CG  1 
ATOM   249  O OD1 . ASP   A 1 35  ? 138.562 155.836 164.080 1.00 83.21  ? 60  ASP   A OD1 1 
ATOM   250  O OD2 . ASP   A 1 35  ? 136.989 154.343 164.426 1.00 77.98  ? 60  ASP   A OD2 1 
ATOM   251  N N   . PRO   A 1 36  ? 139.562 150.812 163.037 1.00 58.21  ? 61  PRO   A N   1 
ATOM   252  C CA  . PRO   A 1 36  ? 139.726 149.464 162.462 1.00 59.14  ? 61  PRO   A CA  1 
ATOM   253  C C   . PRO   A 1 36  ? 138.540 148.918 161.670 1.00 61.06  ? 61  PRO   A C   1 
ATOM   254  O O   . PRO   A 1 36  ? 138.620 147.772 161.218 1.00 68.01  ? 61  PRO   A O   1 
ATOM   255  C CB  . PRO   A 1 36  ? 139.932 148.624 163.723 1.00 59.95  ? 61  PRO   A CB  1 
ATOM   256  C CG  . PRO   A 1 36  ? 139.001 149.251 164.671 1.00 61.57  ? 61  PRO   A CG  1 
ATOM   257  C CD  . PRO   A 1 36  ? 139.097 150.720 164.433 1.00 60.59  ? 61  PRO   A CD  1 
ATOM   258  N N   . ALA   A 1 37  ? 137.462 149.682 161.494 1.00 60.76  ? 62  ALA   A N   1 
ATOM   259  C CA  . ALA   A 1 37  ? 136.192 149.086 161.086 1.00 62.28  ? 62  ALA   A CA  1 
ATOM   260  C C   . ALA   A 1 37  ? 136.217 148.600 159.638 1.00 65.33  ? 62  ALA   A C   1 
ATOM   261  O O   . ALA   A 1 37  ? 135.802 147.468 159.345 1.00 72.24  ? 62  ALA   A O   1 
ATOM   262  C CB  . ALA   A 1 37  ? 135.068 150.094 161.299 1.00 66.14  ? 62  ALA   A CB  1 
ATOM   263  N N   . SER   A 1 38  ? 136.682 149.446 158.715 1.00 59.99  ? 63  SER   A N   1 
ATOM   264  C CA  . SER   A 1 38  ? 136.675 149.079 157.301 1.00 64.83  ? 63  SER   A CA  1 
ATOM   265  C C   . SER   A 1 38  ? 137.542 147.854 157.046 1.00 65.95  ? 63  SER   A C   1 
ATOM   266  O O   . SER   A 1 38  ? 137.187 146.981 156.240 1.00 70.23  ? 63  SER   A O   1 
ATOM   267  C CB  . SER   A 1 38  ? 137.153 150.257 156.455 1.00 68.15  ? 63  SER   A CB  1 
ATOM   268  O OG  . SER   A 1 38  ? 137.066 149.959 155.075 1.00 70.19  ? 63  SER   A OG  1 
ATOM   269  N N   . LEU   A 1 39  ? 138.685 147.774 157.728 1.00 62.02  ? 64  LEU   A N   1 
ATOM   270  C CA  . LEU   A 1 39  ? 139.549 146.609 157.605 1.00 61.07  ? 64  LEU   A CA  1 
ATOM   271  C C   . LEU   A 1 39  ? 138.826 145.348 158.056 1.00 61.13  ? 64  LEU   A C   1 
ATOM   272  O O   . LEU   A 1 39  ? 138.948 144.292 157.424 1.00 66.53  ? 64  LEU   A O   1 
ATOM   273  C CB  . LEU   A 1 39  ? 140.821 146.832 158.422 1.00 60.53  ? 64  LEU   A CB  1 
ATOM   274  C CG  . LEU   A 1 39  ? 141.997 145.880 158.209 1.00 64.39  ? 64  LEU   A CG  1 
ATOM   275  C CD1 . LEU   A 1 39  ? 142.549 145.999 156.804 1.00 67.11  ? 64  LEU   A CD1 1 
ATOM   276  C CD2 . LEU   A 1 39  ? 143.083 146.161 159.224 1.00 66.70  ? 64  LEU   A CD2 1 
ATOM   277  N N   . ALA   A 1 40  ? 138.054 145.441 159.140 1.00 60.12  ? 65  ALA   A N   1 
ATOM   278  C CA  . ALA   A 1 40  ? 137.307 144.284 159.621 1.00 62.70  ? 65  ALA   A CA  1 
ATOM   279  C C   . ALA   A 1 40  ? 136.250 143.848 158.615 1.00 59.49  ? 65  ALA   A C   1 
ATOM   280  O O   . ALA   A 1 40  ? 136.063 142.645 158.380 1.00 65.20  ? 65  ALA   A O   1 
ATOM   281  C CB  . ALA   A 1 40  ? 136.660 144.604 160.964 1.00 62.58  ? 65  ALA   A CB  1 
ATOM   282  N N   . VAL   A 1 41  ? 135.536 144.806 158.024 1.00 52.41  ? 66  VAL   A N   1 
ATOM   283  C CA  . VAL   A 1 41  ? 134.515 144.452 157.040 1.00 54.71  ? 66  VAL   A CA  1 
ATOM   284  C C   . VAL   A 1 41  ? 135.152 143.771 155.835 1.00 62.39  ? 66  VAL   A C   1 
ATOM   285  O O   . VAL   A 1 41  ? 134.629 142.771 155.318 1.00 66.44  ? 66  VAL   A O   1 
ATOM   286  C CB  . VAL   A 1 41  ? 133.711 145.699 156.630 1.00 58.74  ? 66  VAL   A CB  1 
ATOM   287  C CG1 . VAL   A 1 41  ? 132.822 145.398 155.430 1.00 64.61  ? 66  VAL   A CG1 1 
ATOM   288  C CG2 . VAL   A 1 41  ? 132.877 146.192 157.795 1.00 63.39  ? 66  VAL   A CG2 1 
ATOM   289  N N   . PHE   A 1 42  ? 136.285 144.299 155.364 1.00 63.16  ? 67  PHE   A N   1 
ATOM   290  C CA  . PHE   A 1 42  ? 136.958 143.672 154.231 1.00 59.22  ? 67  PHE   A CA  1 
ATOM   291  C C   . PHE   A 1 42  ? 137.449 142.276 154.586 1.00 61.55  ? 67  PHE   A C   1 
ATOM   292  O O   . PHE   A 1 42  ? 137.390 141.364 153.754 1.00 67.43  ? 67  PHE   A O   1 
ATOM   293  C CB  . PHE   A 1 42  ? 138.122 144.529 153.750 1.00 60.50  ? 67  PHE   A CB  1 
ATOM   294  C CG  . PHE   A 1 42  ? 138.859 143.935 152.586 1.00 64.37  ? 67  PHE   A CG  1 
ATOM   295  C CD1 . PHE   A 1 42  ? 138.342 144.019 151.309 1.00 67.43  ? 67  PHE   A CD1 1 
ATOM   296  C CD2 . PHE   A 1 42  ? 140.064 143.288 152.767 1.00 67.50  ? 67  PHE   A CD2 1 
ATOM   297  C CE1 . PHE   A 1 42  ? 139.012 143.471 150.240 1.00 67.06  ? 67  PHE   A CE1 1 
ATOM   298  C CE2 . PHE   A 1 42  ? 140.736 142.740 151.702 1.00 69.55  ? 67  PHE   A CE2 1 
ATOM   299  C CZ  . PHE   A 1 42  ? 140.210 142.833 150.437 1.00 66.57  ? 67  PHE   A CZ  1 
ATOM   300  N N   . ARG   A 1 43  ? 137.954 142.096 155.810 1.00 59.42  ? 68  ARG   A N   1 
ATOM   301  C CA  . ARG   A 1 43  ? 138.343 140.768 156.271 1.00 57.76  ? 68  ARG   A CA  1 
ATOM   302  C C   . ARG   A 1 43  ? 137.173 139.801 156.185 1.00 58.20  ? 68  ARG   A C   1 
ATOM   303  O O   . ARG   A 1 43  ? 137.315 138.686 155.665 1.00 64.71  ? 68  ARG   A O   1 
ATOM   304  C CB  . ARG   A 1 43  ? 138.866 140.862 157.707 1.00 59.75  ? 68  ARG   A CB  1 
ATOM   305  C CG  . ARG   A 1 43  ? 139.052 139.542 158.471 1.00 60.41  ? 68  ARG   A CG  1 
ATOM   306  C CD  . ARG   A 1 43  ? 139.407 139.799 159.923 1.00 66.60  ? 68  ARG   A CD  1 
ATOM   307  N NE  . ARG   A 1 43  ? 138.328 140.470 160.643 1.00 65.25  ? 68  ARG   A NE  1 
ATOM   308  C CZ  . ARG   A 1 43  ? 137.247 139.875 161.128 1.00 61.77  ? 68  ARG   A CZ  1 
ATOM   309  N NH1 . ARG   A 1 43  ? 137.041 138.576 160.982 1.00 66.24  ? 68  ARG   A NH1 1 
ATOM   310  N NH2 . ARG   A 1 43  ? 136.344 140.603 161.776 1.00 64.08  ? 68  ARG   A NH2 1 
ATOM   311  N N   . PHE   A 1 44  ? 136.014 140.209 156.703 1.00 56.22  ? 69  PHE   A N   1 
ATOM   312  C CA  . PHE   A 1 44  ? 134.851 139.329 156.704 1.00 56.28  ? 69  PHE   A CA  1 
ATOM   313  C C   . PHE   A 1 44  ? 134.449 138.955 155.285 1.00 61.47  ? 69  PHE   A C   1 
ATOM   314  O O   . PHE   A 1 44  ? 134.207 137.778 154.982 1.00 65.35  ? 69  PHE   A O   1 
ATOM   315  C CB  . PHE   A 1 44  ? 133.692 140.004 157.435 1.00 57.73  ? 69  PHE   A CB  1 
ATOM   316  C CG  . PHE   A 1 44  ? 132.462 139.154 157.543 1.00 58.02  ? 69  PHE   A CG  1 
ATOM   317  C CD1 . PHE   A 1 44  ? 132.316 138.257 158.580 1.00 63.97  ? 69  PHE   A CD1 1 
ATOM   318  C CD2 . PHE   A 1 44  ? 131.443 139.264 156.617 1.00 60.66  ? 69  PHE   A CD2 1 
ATOM   319  C CE1 . PHE   A 1 44  ? 131.186 137.480 158.685 1.00 68.71  ? 69  PHE   A CE1 1 
ATOM   320  C CE2 . PHE   A 1 44  ? 130.313 138.489 156.716 1.00 62.68  ? 69  PHE   A CE2 1 
ATOM   321  C CZ  . PHE   A 1 44  ? 130.183 137.598 157.750 1.00 69.07  ? 69  PHE   A CZ  1 
ATOM   322  N N   . LEU   A 1 45  ? 134.380 139.945 154.393 1.00 62.84  ? 70  LEU   A N   1 
ATOM   323  C CA  . LEU   A 1 45  ? 133.940 139.658 153.031 1.00 58.94  ? 70  LEU   A CA  1 
ATOM   324  C C   . LEU   A 1 45  ? 134.946 138.784 152.292 1.00 61.43  ? 70  LEU   A C   1 
ATOM   325  O O   . LEU   A 1 45  ? 134.554 137.858 151.572 1.00 69.05  ? 70  LEU   A O   1 
ATOM   326  C CB  . LEU   A 1 45  ? 133.691 140.957 152.267 1.00 58.19  ? 70  LEU   A CB  1 
ATOM   327  C CG  . LEU   A 1 45  ? 132.584 141.871 152.800 1.00 61.55  ? 70  LEU   A CG  1 
ATOM   328  C CD1 . LEU   A 1 45  ? 132.443 143.083 151.903 1.00 65.98  ? 70  LEU   A CD1 1 
ATOM   329  C CD2 . LEU   A 1 45  ? 131.254 141.153 152.925 1.00 62.20  ? 70  LEU   A CD2 1 
ATOM   330  N N   . PHE   A 1 46  ? 136.244 139.048 152.461 1.00 58.99  ? 71  PHE   A N   1 
ATOM   331  C CA  . PHE   A 1 46  ? 137.256 138.224 151.810 1.00 58.23  ? 71  PHE   A CA  1 
ATOM   332  C C   . PHE   A 1 46  ? 137.195 136.788 152.307 1.00 59.77  ? 71  PHE   A C   1 
ATOM   333  O O   . PHE   A 1 46  ? 137.272 135.843 151.510 1.00 67.44  ? 71  PHE   A O   1 
ATOM   334  C CB  . PHE   A 1 46  ? 138.641 138.819 152.056 1.00 61.80  ? 71  PHE   A CB  1 
ATOM   335  C CG  . PHE   A 1 46  ? 139.765 137.994 151.511 1.00 61.42  ? 71  PHE   A CG  1 
ATOM   336  C CD1 . PHE   A 1 46  ? 140.104 138.060 150.178 1.00 60.30  ? 71  PHE   A CD1 1 
ATOM   337  C CD2 . PHE   A 1 46  ? 140.497 137.165 152.338 1.00 65.42  ? 71  PHE   A CD2 1 
ATOM   338  C CE1 . PHE   A 1 46  ? 141.138 137.308 149.675 1.00 61.09  ? 71  PHE   A CE1 1 
ATOM   339  C CE2 . PHE   A 1 46  ? 141.534 136.410 151.840 1.00 66.06  ? 71  PHE   A CE2 1 
ATOM   340  C CZ  . PHE   A 1 46  ? 141.854 136.484 150.506 1.00 61.23  ? 71  PHE   A CZ  1 
ATOM   341  N N   . GLY   A 1 47  ? 137.046 136.601 153.619 1.00 57.20  ? 72  GLY   A N   1 
ATOM   342  C CA  . GLY   A 1 47  ? 136.925 135.256 154.150 1.00 59.32  ? 72  GLY   A CA  1 
ATOM   343  C C   . GLY   A 1 47  ? 135.711 134.526 153.612 1.00 59.56  ? 72  GLY   A C   1 
ATOM   344  O O   . GLY   A 1 47  ? 135.802 133.362 153.216 1.00 64.59  ? 72  GLY   A O   1 
ATOM   345  N N   . PHE   A 1 48  ? 134.562 135.204 153.577 1.00 59.45  ? 73  PHE   A N   1 
ATOM   346  C CA  . PHE   A 1 48  ? 133.347 134.573 153.073 1.00 62.30  ? 73  PHE   A CA  1 
ATOM   347  C C   . PHE   A 1 48  ? 133.494 134.190 151.606 1.00 62.34  ? 73  PHE   A C   1 
ATOM   348  O O   . PHE   A 1 48  ? 133.101 133.087 151.195 1.00 66.83  ? 73  PHE   A O   1 
ATOM   349  C CB  . PHE   A 1 48  ? 132.164 135.519 153.273 1.00 63.17  ? 73  PHE   A CB  1 
ATOM   350  C CG  . PHE   A 1 48  ? 130.842 134.932 152.889 1.00 63.01  ? 73  PHE   A CG  1 
ATOM   351  C CD1 . PHE   A 1 48  ? 130.285 133.908 153.627 1.00 69.06  ? 73  PHE   A CD1 1 
ATOM   352  C CD2 . PHE   A 1 48  ? 130.146 135.421 151.802 1.00 67.79  ? 73  PHE   A CD2 1 
ATOM   353  C CE1 . PHE   A 1 48  ? 129.066 133.371 153.278 1.00 74.84  ? 73  PHE   A CE1 1 
ATOM   354  C CE2 . PHE   A 1 48  ? 128.929 134.891 151.448 1.00 75.88  ? 73  PHE   A CE2 1 
ATOM   355  C CZ  . PHE   A 1 48  ? 128.385 133.864 152.187 1.00 76.92  ? 73  PHE   A CZ  1 
ATOM   356  N N   . LEU   A 1 49  ? 134.079 135.079 150.803 1.00 60.54  ? 74  LEU   A N   1 
ATOM   357  C CA  . LEU   A 1 49  ? 134.231 134.793 149.383 1.00 60.25  ? 74  LEU   A CA  1 
ATOM   358  C C   . LEU   A 1 49  ? 135.192 133.635 149.150 1.00 62.67  ? 74  LEU   A C   1 
ATOM   359  O O   . LEU   A 1 49  ? 134.937 132.781 148.296 1.00 67.56  ? 74  LEU   A O   1 
ATOM   360  C CB  . LEU   A 1 49  ? 134.697 136.046 148.643 1.00 61.17  ? 74  LEU   A CB  1 
ATOM   361  C CG  . LEU   A 1 49  ? 133.684 137.193 148.565 1.00 63.03  ? 74  LEU   A CG  1 
ATOM   362  C CD1 . LEU   A 1 49  ? 134.330 138.444 148.003 1.00 64.88  ? 74  LEU   A CD1 1 
ATOM   363  C CD2 . LEU   A 1 49  ? 132.479 136.815 147.727 1.00 66.90  ? 74  LEU   A CD2 1 
ATOM   364  N N   . MET   A 1 50  ? 136.299 133.574 149.894 1.00 61.57  ? 75  MET   A N   1 
ATOM   365  C CA  . MET   A 1 50  ? 137.212 132.447 149.722 1.00 59.96  ? 75  MET   A CA  1 
ATOM   366  C C   . MET   A 1 50  ? 136.585 131.143 150.204 1.00 60.86  ? 75  MET   A C   1 
ATOM   367  O O   . MET   A 1 50  ? 136.840 130.077 149.625 1.00 67.74  ? 75  MET   A O   1 
ATOM   368  C CB  . MET   A 1 50  ? 138.532 132.708 150.447 1.00 61.68  ? 75  MET   A CB  1 
ATOM   369  C CG  . MET   A 1 50  ? 139.376 133.851 149.871 1.00 65.30  ? 75  MET   A CG  1 
ATOM   370  S SD  . MET   A 1 50  ? 139.676 133.827 148.090 1.00 78.96  ? 75  MET   A SD  1 
ATOM   371  C CE  . MET   A 1 50  ? 140.655 132.341 147.891 1.00 69.88  ? 75  MET   A CE  1 
ATOM   372  N N   . VAL   A 1 51  ? 135.767 131.200 151.259 1.00 59.82  ? 76  VAL   A N   1 
ATOM   373  C CA  . VAL   A 1 51  ? 135.038 130.013 151.696 1.00 58.31  ? 76  VAL   A CA  1 
ATOM   374  C C   . VAL   A 1 51  ? 134.143 129.504 150.576 1.00 60.76  ? 76  VAL   A C   1 
ATOM   375  O O   . VAL   A 1 51  ? 134.092 128.300 150.301 1.00 63.45  ? 76  VAL   A O   1 
ATOM   376  C CB  . VAL   A 1 51  ? 134.230 130.317 152.972 1.00 63.82  ? 76  VAL   A CB  1 
ATOM   377  C CG1 . VAL   A 1 51  ? 133.163 129.258 153.221 1.00 61.94  ? 76  VAL   A CG1 1 
ATOM   378  C CG2 . VAL   A 1 51  ? 135.151 130.403 154.174 1.00 68.81  ? 76  VAL   A CG2 1 
ATOM   379  N N   . LEU   A 1 52  ? 133.421 130.408 149.914 1.00 64.11  ? 77  LEU   A N   1 
ATOM   380  C CA  . LEU   A 1 52  ? 132.589 129.975 148.795 1.00 62.10  ? 77  LEU   A CA  1 
ATOM   381  C C   . LEU   A 1 52  ? 133.429 129.526 147.604 1.00 63.11  ? 77  LEU   A C   1 
ATOM   382  O O   . LEU   A 1 52  ? 132.976 128.698 146.808 1.00 66.37  ? 77  LEU   A O   1 
ATOM   383  C CB  . LEU   A 1 52  ? 131.640 131.094 148.367 1.00 64.69  ? 77  LEU   A CB  1 
ATOM   384  C CG  . LEU   A 1 52  ? 130.511 131.478 149.323 1.00 68.75  ? 77  LEU   A CG  1 
ATOM   385  C CD1 . LEU   A 1 52  ? 129.739 132.649 148.750 1.00 73.17  ? 77  LEU   A CD1 1 
ATOM   386  C CD2 . LEU   A 1 52  ? 129.578 130.311 149.592 1.00 71.06  ? 77  LEU   A CD2 1 
ATOM   387  N N   . ASP   A 1 53  ? 134.644 130.054 147.464 1.00 63.96  ? 78  ASP   A N   1 
ATOM   388  C CA  . ASP   A 1 53  ? 135.443 129.789 146.275 1.00 64.78  ? 78  ASP   A CA  1 
ATOM   389  C C   . ASP   A 1 53  ? 136.194 128.468 146.348 1.00 63.09  ? 78  ASP   A C   1 
ATOM   390  O O   . ASP   A 1 53  ? 136.490 127.879 145.303 1.00 68.12  ? 78  ASP   A O   1 
ATOM   391  C CB  . ASP   A 1 53  ? 136.441 130.927 146.061 1.00 71.23  ? 78  ASP   A CB  1 
ATOM   392  C CG  . ASP   A 1 53  ? 137.156 130.836 144.729 1.00 78.75  ? 78  ASP   A CG  1 
ATOM   393  O OD1 . ASP   A 1 53  ? 136.642 130.153 143.820 1.00 76.93  ? 78  ASP   A OD1 1 
ATOM   394  O OD2 . ASP   A 1 53  ? 138.236 131.448 144.591 1.00 83.13  ? 78  ASP   A OD2 1 
ATOM   395  N N   . ILE   A 1 54  ? 136.527 127.993 147.552 1.00 64.44  ? 79  ILE   A N   1 
ATOM   396  C CA  . ILE   A 1 54  ? 137.314 126.761 147.666 1.00 59.39  ? 79  ILE   A CA  1 
ATOM   397  C C   . ILE   A 1 54  ? 136.597 125.560 147.054 1.00 61.04  ? 79  ILE   A C   1 
ATOM   398  O O   . ILE   A 1 54  ? 137.238 124.809 146.301 1.00 68.02  ? 79  ILE   A O   1 
ATOM   399  C CB  . ILE   A 1 54  ? 137.739 126.537 149.127 1.00 57.58  ? 79  ILE   A CB  1 
ATOM   400  C CG1 . ILE   A 1 54  ? 138.888 127.484 149.479 1.00 66.79  ? 79  ILE   A CG1 1 
ATOM   401  C CG2 . ILE   A 1 54  ? 138.156 125.085 149.370 1.00 61.93  ? 79  ILE   A CG2 1 
ATOM   402  C CD1 . ILE   A 1 54  ? 139.141 127.642 150.968 1.00 69.56  ? 79  ILE   A CD1 1 
ATOM   403  N N   . PRO   A 1 55  ? 135.310 125.313 147.317 1.00 59.35  ? 80  PRO   A N   1 
ATOM   404  C CA  . PRO   A 1 55  ? 134.659 124.142 146.715 1.00 62.39  ? 80  PRO   A CA  1 
ATOM   405  C C   . PRO   A 1 55  ? 134.272 124.297 145.252 1.00 64.46  ? 80  PRO   A C   1 
ATOM   406  O O   . PRO   A 1 55  ? 133.745 123.338 144.679 1.00 66.12  ? 80  PRO   A O   1 
ATOM   407  C CB  . PRO   A 1 55  ? 133.404 123.958 147.584 1.00 62.37  ? 80  PRO   A CB  1 
ATOM   408  C CG  . PRO   A 1 55  ? 133.653 124.744 148.805 1.00 65.96  ? 80  PRO   A CG  1 
ATOM   409  C CD  . PRO   A 1 55  ? 134.440 125.908 148.344 1.00 65.17  ? 80  PRO   A CD  1 
ATOM   410  N N   . GLN   A 1 56  ? 134.516 125.450 144.625 1.00 65.12  ? 81  GLN   A N   1 
ATOM   411  C CA  . GLN   A 1 56  ? 134.035 125.728 143.276 1.00 61.94  ? 81  GLN   A CA  1 
ATOM   412  C C   . GLN   A 1 56  ? 135.163 125.823 142.259 1.00 65.36  ? 81  GLN   A C   1 
ATOM   413  O O   . GLN   A 1 56  ? 135.147 125.102 141.258 1.00 72.35  ? 81  GLN   A O   1 
ATOM   414  C CB  . GLN   A 1 56  ? 133.221 127.028 143.268 1.00 66.48  ? 81  GLN   A CB  1 
ATOM   415  C CG  . GLN   A 1 56  ? 131.890 126.932 143.980 1.00 71.13  ? 81  GLN   A CG  1 
ATOM   416  C CD  . GLN   A 1 56  ? 131.047 128.177 143.799 1.00 77.68  ? 81  GLN   A CD  1 
ATOM   417  O OE1 . GLN   A 1 56  ? 131.393 129.066 143.024 1.00 78.79  ? 81  GLN   A OE1 1 
ATOM   418  N NE2 . GLN   A 1 56  ? 129.934 128.248 144.518 1.00 79.96  ? 81  GLN   A NE2 1 
ATOM   419  N N   . GLU   A 1 57  ? 136.149 126.691 142.490 1.00 64.31  ? 82  GLU   A N   1 
ATOM   420  C CA  . GLU   A 1 57  ? 137.211 126.940 141.523 1.00 68.84  ? 82  GLU   A CA  1 
ATOM   421  C C   . GLU   A 1 57  ? 138.522 126.263 141.880 1.00 71.26  ? 82  GLU   A C   1 
ATOM   422  O O   . GLU   A 1 57  ? 139.233 125.807 140.980 1.00 75.58  ? 82  GLU   A O   1 
ATOM   423  C CB  . GLU   A 1 57  ? 137.457 128.443 141.381 1.00 74.26  ? 82  GLU   A CB  1 
ATOM   424  C CG  . GLU   A 1 57  ? 138.329 128.808 140.193 1.00 82.22  ? 82  GLU   A CG  1 
ATOM   425  C CD  . GLU   A 1 57  ? 138.392 130.301 139.946 1.00 88.53  ? 82  GLU   A CD  1 
ATOM   426  O OE1 . GLU   A 1 57  ? 137.817 131.064 140.750 1.00 90.68  ? 82  GLU   A OE1 1 
ATOM   427  O OE2 . GLU   A 1 57  ? 139.015 130.712 138.945 1.00 84.56  ? 82  GLU   A OE2 1 
ATOM   428  N N   . ARG   A 1 58  ? 138.868 126.196 143.166 1.00 63.71  ? 83  ARG   A N   1 
ATOM   429  C CA  . ARG   A 1 58  ? 140.125 125.571 143.558 1.00 63.36  ? 83  ARG   A CA  1 
ATOM   430  C C   . ARG   A 1 58  ? 140.147 124.093 143.200 1.00 69.38  ? 83  ARG   A C   1 
ATOM   431  O O   . ARG   A 1 58  ? 141.221 123.531 142.962 1.00 70.80  ? 83  ARG   A O   1 
ATOM   432  C CB  . ARG   A 1 58  ? 140.361 125.761 145.055 1.00 67.32  ? 83  ARG   A CB  1 
ATOM   433  C CG  . ARG   A 1 58  ? 140.528 127.212 145.494 1.00 70.28  ? 83  ARG   A CG  1 
ATOM   434  C CD  . ARG   A 1 58  ? 141.921 127.760 145.226 1.00 67.02  ? 83  ARG   A CD  1 
ATOM   435  N NE  . ARG   A 1 58  ? 142.129 128.135 143.832 1.00 70.25  ? 83  ARG   A NE  1 
ATOM   436  C CZ  . ARG   A 1 58  ? 141.731 129.274 143.278 1.00 73.98  ? 83  ARG   A CZ  1 
ATOM   437  N NH1 . ARG   A 1 58  ? 141.059 130.186 143.964 1.00 75.75  ? 83  ARG   A NH1 1 
ATOM   438  N NH2 . ARG   A 1 58  ? 142.014 129.505 142.000 1.00 74.33  ? 83  ARG   A NH2 1 
ATOM   439  N N   . GLY   A 1 59  ? 138.983 123.448 143.170 1.00 71.39  ? 84  GLY   A N   1 
ATOM   440  C CA  . GLY   A 1 59  ? 138.864 122.103 142.643 1.00 67.03  ? 84  GLY   A CA  1 
ATOM   441  C C   . GLY   A 1 59  ? 138.712 121.029 143.696 1.00 61.39  ? 84  GLY   A C   1 
ATOM   442  O O   . GLY   A 1 59  ? 139.261 119.935 143.546 1.00 66.62  ? 84  GLY   A O   1 
ATOM   443  N N   . LEU   A 1 60  ? 137.972 121.320 144.765 1.00 57.35  ? 85  LEU   A N   1 
ATOM   444  C CA  . LEU   A 1 60  ? 137.733 120.308 145.785 1.00 61.61  ? 85  LEU   A CA  1 
ATOM   445  C C   . LEU   A 1 60  ? 136.724 119.267 145.322 1.00 64.64  ? 85  LEU   A C   1 
ATOM   446  O O   . LEU   A 1 60  ? 136.845 118.091 145.682 1.00 65.62  ? 85  LEU   A O   1 
ATOM   447  C CB  . LEU   A 1 60  ? 137.255 120.966 147.079 1.00 60.15  ? 85  LEU   A CB  1 
ATOM   448  C CG  . LEU   A 1 60  ? 137.062 120.072 148.305 1.00 58.64  ? 85  LEU   A CG  1 
ATOM   449  C CD1 . LEU   A 1 60  ? 138.329 119.320 148.648 1.00 61.38  ? 85  LEU   A CD1 1 
ATOM   450  C CD2 . LEU   A 1 60  ? 136.610 120.906 149.484 1.00 56.42  ? 85  LEU   A CD2 1 
ATOM   451  N N   . SER   A 1 61  ? 135.728 119.673 144.533 1.00 60.74  ? 86  SER   A N   1 
ATOM   452  C CA  . SER   A 1 61  ? 134.762 118.713 144.015 1.00 59.29  ? 86  SER   A CA  1 
ATOM   453  C C   . SER   A 1 61  ? 135.386 117.802 142.968 1.00 62.55  ? 86  SER   A C   1 
ATOM   454  O O   . SER   A 1 61  ? 135.027 116.623 142.883 1.00 69.72  ? 86  SER   A O   1 
ATOM   455  C CB  . SER   A 1 61  ? 133.561 119.447 143.427 1.00 61.87  ? 86  SER   A CB  1 
ATOM   456  O OG  . SER   A 1 61  ? 133.950 120.267 142.341 1.00 67.67  ? 86  SER   A OG  1 
ATOM   457  N N   . SER   A 1 62  ? 136.311 118.325 142.170 1.00 61.99  ? 87  SER   A N   1 
ATOM   458  C CA  . SER   A 1 62  ? 136.970 117.571 141.114 1.00 62.97  ? 87  SER   A CA  1 
ATOM   459  C C   . SER   A 1 62  ? 138.275 116.926 141.562 1.00 64.54  ? 87  SER   A C   1 
ATOM   460  O O   . SER   A 1 62  ? 138.974 116.342 140.728 1.00 71.60  ? 87  SER   A O   1 
ATOM   461  C CB  . SER   A 1 62  ? 137.237 118.489 139.918 1.00 65.32  ? 87  SER   A CB  1 
ATOM   462  O OG  . SER   A 1 62  ? 137.841 117.780 138.849 1.00 79.88  ? 87  SER   A OG  1 
ATOM   463  N N   . LEU   A 1 63  ? 138.623 117.013 142.846 1.00 64.19  ? 88  LEU   A N   1 
ATOM   464  C CA  . LEU   A 1 63  ? 139.919 116.526 143.301 1.00 63.06  ? 88  LEU   A CA  1 
ATOM   465  C C   . LEU   A 1 63  ? 140.036 115.011 143.231 1.00 65.73  ? 88  LEU   A C   1 
ATOM   466  O O   . LEU   A 1 63  ? 141.156 114.493 143.229 1.00 69.50  ? 88  LEU   A O   1 
ATOM   467  C CB  . LEU   A 1 63  ? 140.174 116.986 144.734 1.00 61.19  ? 88  LEU   A CB  1 
ATOM   468  C CG  . LEU   A 1 63  ? 141.626 117.062 145.196 1.00 63.32  ? 88  LEU   A CG  1 
ATOM   469  C CD1 . LEU   A 1 63  ? 142.353 118.228 144.545 1.00 66.72  ? 88  LEU   A CD1 1 
ATOM   470  C CD2 . LEU   A 1 63  ? 141.664 117.182 146.703 1.00 64.37  ? 88  LEU   A CD2 1 
ATOM   471  N N   . ASP   A 1 64  ? 138.919 114.290 143.171 1.00 70.64  ? 89  ASP   A N   1 
ATOM   472  C CA  . ASP   A 1 64  ? 138.957 112.837 143.084 1.00 72.60  ? 89  ASP   A CA  1 
ATOM   473  C C   . ASP   A 1 64  ? 139.218 112.332 141.672 1.00 71.66  ? 89  ASP   A C   1 
ATOM   474  O O   . ASP   A 1 64  ? 139.368 111.119 141.492 1.00 73.42  ? 89  ASP   A O   1 
ATOM   475  C CB  . ASP   A 1 64  ? 137.643 112.244 143.596 1.00 77.61  ? 89  ASP   A CB  1 
ATOM   476  C CG  . ASP   A 1 64  ? 136.451 112.653 142.755 1.00 84.04  ? 89  ASP   A CG  1 
ATOM   477  O OD1 . ASP   A 1 64  ? 136.492 113.750 142.158 1.00 84.92  ? 89  ASP   A OD1 1 
ATOM   478  O OD2 . ASP   A 1 64  ? 135.472 111.880 142.689 1.00 85.53  ? 89  ASP   A OD2 1 
ATOM   479  N N   . ARG   A 1 65  ? 139.270 113.222 140.675 1.00 71.73  ? 90  ARG   A N   1 
ATOM   480  C CA  . ARG   A 1 65  ? 139.584 112.854 139.301 1.00 71.23  ? 90  ARG   A CA  1 
ATOM   481  C C   . ARG   A 1 65  ? 140.715 113.693 138.718 1.00 68.77  ? 90  ARG   A C   1 
ATOM   482  O O   . ARG   A 1 65  ? 140.879 113.716 137.493 1.00 72.99  ? 90  ARG   A O   1 
ATOM   483  C CB  . ARG   A 1 65  ? 138.331 112.969 138.424 1.00 75.27  ? 90  ARG   A CB  1 
ATOM   484  C CG  . ARG   A 1 65  ? 137.660 114.333 138.454 1.00 80.25  ? 90  ARG   A CG  1 
ATOM   485  C CD  . ARG   A 1 65  ? 136.411 114.359 137.586 1.00 89.16  ? 90  ARG   A CD  1 
ATOM   486  N NE  . ARG   A 1 65  ? 135.392 113.420 138.045 1.00 97.35  ? 90  ARG   A NE  1 
ATOM   487  C CZ  . ARG   A 1 65  ? 134.197 113.264 137.486 1.00 101.30 ? 90  ARG   A CZ  1 
ATOM   488  N NH1 . ARG   A 1 65  ? 133.819 113.978 136.436 1.00 99.59  ? 90  ARG   A NH1 1 
ATOM   489  N NH2 . ARG   A 1 65  ? 133.358 112.366 137.994 1.00 98.30  ? 90  ARG   A NH2 1 
ATOM   490  N N   . LYS   A 1 66  ? 141.494 114.376 139.555 1.00 67.14  ? 91  LYS   A N   1 
ATOM   491  C CA  . LYS   A 1 66  ? 142.654 115.157 139.141 1.00 63.51  ? 91  LYS   A CA  1 
ATOM   492  C C   . LYS   A 1 66  ? 143.955 114.641 139.730 1.00 66.61  ? 91  LYS   A C   1 
ATOM   493  O O   . LYS   A 1 66  ? 144.975 114.630 139.036 1.00 72.85  ? 91  LYS   A O   1 
ATOM   494  C CB  . LYS   A 1 66  ? 142.464 116.626 139.541 1.00 65.69  ? 91  LYS   A CB  1 
ATOM   495  C CG  . LYS   A 1 66  ? 143.529 117.570 139.014 1.00 76.57  ? 91  LYS   A CG  1 
ATOM   496  C CD  . LYS   A 1 66  ? 143.187 119.013 139.334 1.00 82.69  ? 91  LYS   A CD  1 
ATOM   497  C CE  . LYS   A 1 66  ? 144.309 119.956 138.940 1.00 82.22  ? 91  LYS   A CE  1 
ATOM   498  N NZ  . LYS   A 1 66  ? 144.588 119.918 137.480 1.00 86.20  ? 91  LYS   A NZ  1 
ATOM   499  N N   . TYR   A 1 67  ? 143.945 114.216 140.992 1.00 64.58  ? 92  TYR   A N   1 
ATOM   500  C CA  . TYR   A 1 67  ? 145.104 113.649 141.673 1.00 64.64  ? 92  TYR   A CA  1 
ATOM   501  C C   . TYR   A 1 67  ? 144.864 112.185 142.028 1.00 67.87  ? 92  TYR   A C   1 
ATOM   502  O O   . TYR   A 1 67  ? 145.303 111.700 143.071 1.00 73.26  ? 92  TYR   A O   1 
ATOM   503  C CB  . TYR   A 1 67  ? 145.441 114.453 142.925 1.00 64.93  ? 92  TYR   A CB  1 
ATOM   504  C CG  . TYR   A 1 67  ? 145.860 115.875 142.645 1.00 67.13  ? 92  TYR   A CG  1 
ATOM   505  C CD1 . TYR   A 1 67  ? 147.134 116.164 142.188 1.00 70.05  ? 92  TYR   A CD1 1 
ATOM   506  C CD2 . TYR   A 1 67  ? 144.985 116.929 142.843 1.00 70.78  ? 92  TYR   A CD2 1 
ATOM   507  C CE1 . TYR   A 1 67  ? 147.523 117.460 141.931 1.00 70.44  ? 92  TYR   A CE1 1 
ATOM   508  C CE2 . TYR   A 1 67  ? 145.366 118.229 142.590 1.00 74.00  ? 92  TYR   A CE2 1 
ATOM   509  C CZ  . TYR   A 1 67  ? 146.635 118.488 142.135 1.00 74.37  ? 92  TYR   A CZ  1 
ATOM   510  O OH  . TYR   A 1 67  ? 147.020 119.783 141.880 1.00 77.36  ? 92  TYR   A OH  1 
ATOM   511  N N   . LEU   A 1 68  ? 144.157 111.472 141.156 1.00 65.34  ? 93  LEU   A N   1 
ATOM   512  C CA  . LEU   A 1 68  ? 143.813 110.083 141.419 1.00 68.47  ? 93  LEU   A CA  1 
ATOM   513  C C   . LEU   A 1 68  ? 145.065 109.222 141.513 1.00 71.76  ? 93  LEU   A C   1 
ATOM   514  O O   . LEU   A 1 68  ? 145.998 109.362 140.719 1.00 75.63  ? 93  LEU   A O   1 
ATOM   515  C CB  . LEU   A 1 68  ? 142.895 109.559 140.314 1.00 69.95  ? 93  LEU   A CB  1 
ATOM   516  C CG  . LEU   A 1 68  ? 142.439 108.101 140.383 1.00 71.56  ? 93  LEU   A CG  1 
ATOM   517  C CD1 . LEU   A 1 68  ? 141.746 107.797 141.699 1.00 75.60  ? 93  LEU   A CD1 1 
ATOM   518  C CD2 . LEU   A 1 68  ? 141.518 107.801 139.217 1.00 70.39  ? 93  LEU   A CD2 1 
ATOM   519  N N   . ASP   A 1 69  ? 145.080 108.326 142.496 1.00 73.35  ? 94  ASP   A N   1 
ATOM   520  C CA  . ASP   A 1 69  ? 146.208 107.425 142.667 1.00 75.83  ? 94  ASP   A CA  1 
ATOM   521  C C   . ASP   A 1 69  ? 146.239 106.393 141.548 1.00 77.45  ? 94  ASP   A C   1 
ATOM   522  O O   . ASP   A 1 69  ? 145.199 105.892 141.114 1.00 78.49  ? 94  ASP   A O   1 
ATOM   523  C CB  . ASP   A 1 69  ? 146.126 106.722 144.020 1.00 82.75  ? 94  ASP   A CB  1 
ATOM   524  C CG  . ASP   A 1 69  ? 146.087 107.694 145.181 1.00 88.37  ? 94  ASP   A CG  1 
ATOM   525  O OD1 . ASP   A 1 69  ? 146.647 108.802 145.049 1.00 84.84  ? 94  ASP   A OD1 1 
ATOM   526  O OD2 . ASP   A 1 69  ? 145.496 107.349 146.225 1.00 88.97  ? 94  ASP   A OD2 1 
ATOM   527  N N   . GLY   A 1 70  ? 147.445 106.079 141.079 1.00 77.18  ? 95  GLY   A N   1 
ATOM   528  C CA  . GLY   A 1 70  ? 147.646 105.066 140.069 1.00 76.48  ? 95  GLY   A CA  1 
ATOM   529  C C   . GLY   A 1 70  ? 147.573 105.554 138.639 1.00 77.75  ? 95  GLY   A C   1 
ATOM   530  O O   . GLY   A 1 70  ? 148.005 104.831 137.734 1.00 77.00  ? 95  GLY   A O   1 
ATOM   531  N N   . LEU   A 1 71  ? 147.046 106.752 138.403 1.00 77.95  ? 96  LEU   A N   1 
ATOM   532  C CA  . LEU   A 1 71  ? 146.938 107.278 137.051 1.00 74.03  ? 96  LEU   A CA  1 
ATOM   533  C C   . LEU   A 1 71  ? 148.254 107.910 136.626 1.00 81.86  ? 96  LEU   A C   1 
ATOM   534  O O   . LEU   A 1 71  ? 148.909 108.606 137.408 1.00 85.97  ? 96  LEU   A O   1 
ATOM   535  C CB  . LEU   A 1 71  ? 145.813 108.308 136.970 1.00 74.74  ? 96  LEU   A CB  1 
ATOM   536  C CG  . LEU   A 1 71  ? 145.452 108.830 135.578 1.00 79.85  ? 96  LEU   A CG  1 
ATOM   537  C CD1 . LEU   A 1 71  ? 144.883 107.720 134.705 1.00 79.91  ? 96  LEU   A CD1 1 
ATOM   538  C CD2 . LEU   A 1 71  ? 144.470 109.985 135.684 1.00 79.91  ? 96  LEU   A CD2 1 
ATOM   539  N N   . ASP   A 1 72  ? 148.635 107.666 135.374 1.00 82.60  ? 97  ASP   A N   1 
ATOM   540  C CA  . ASP   A 1 72  ? 149.864 108.215 134.805 1.00 77.56  ? 97  ASP   A CA  1 
ATOM   541  C C   . ASP   A 1 72  ? 149.516 109.489 134.045 1.00 77.29  ? 97  ASP   A C   1 
ATOM   542  O O   . ASP   A 1 72  ? 148.881 109.438 132.987 1.00 78.75  ? 97  ASP   A O   1 
ATOM   543  C CB  . ASP   A 1 72  ? 150.563 107.195 133.905 1.00 78.33  ? 97  ASP   A CB  1 
ATOM   544  C CG  . ASP   A 1 72  ? 149.639 106.583 132.867 1.00 84.30  ? 97  ASP   A CG  1 
ATOM   545  O OD1 . ASP   A 1 72  ? 148.415 106.811 132.948 1.00 83.59  ? 97  ASP   A OD1 1 
ATOM   546  O OD2 . ASP   A 1 72  ? 150.139 105.869 131.973 1.00 84.49  ? 97  ASP   A OD2 1 
ATOM   547  N N   . VAL   A 1 73  ? 149.919 110.635 134.596 1.00 70.68  ? 98  VAL   A N   1 
ATOM   548  C CA  . VAL   A 1 73  ? 149.661 111.940 134.004 1.00 69.15  ? 98  VAL   A CA  1 
ATOM   549  C C   . VAL   A 1 73  ? 150.956 112.739 134.041 1.00 69.91  ? 98  VAL   A C   1 
ATOM   550  O O   . VAL   A 1 73  ? 151.863 112.459 134.827 1.00 74.44  ? 98  VAL   A O   1 
ATOM   551  C CB  . VAL   A 1 73  ? 148.530 112.699 134.739 1.00 71.50  ? 98  VAL   A CB  1 
ATOM   552  C CG1 . VAL   A 1 73  ? 148.030 113.881 133.909 1.00 71.53  ? 98  VAL   A CG1 1 
ATOM   553  C CG2 . VAL   A 1 73  ? 147.384 111.756 135.083 1.00 70.99  ? 98  VAL   A CG2 1 
ATOM   554  N N   . CYS   A 1 74  ? 151.034 113.742 133.169 1.00 68.77  ? 99  CYS   A N   1 
ATOM   555  C CA  . CYS   A 1 74  ? 152.169 114.652 133.105 1.00 67.62  ? 99  CYS   A CA  1 
ATOM   556  C C   . CYS   A 1 74  ? 151.817 115.933 133.848 1.00 72.26  ? 99  CYS   A C   1 
ATOM   557  O O   . CYS   A 1 74  ? 150.869 116.632 133.473 1.00 73.59  ? 99  CYS   A O   1 
ATOM   558  C CB  . CYS   A 1 74  ? 152.537 114.958 131.656 1.00 62.28  ? 99  CYS   A CB  1 
ATOM   559  S SG  . CYS   A 1 74  ? 152.795 113.496 130.641 1.00 89.72  ? 99  CYS   A SG  1 
ATOM   560  N N   . ARG   A 1 75  ? 152.576 116.236 134.894 1.00 72.24  ? 100 ARG   A N   1 
ATOM   561  C CA  . ARG   A 1 75  ? 152.359 117.425 135.700 1.00 69.56  ? 100 ARG   A CA  1 
ATOM   562  C C   . ARG   A 1 75  ? 153.179 118.588 135.158 1.00 66.25  ? 100 ARG   A C   1 
ATOM   563  O O   . ARG   A 1 75  ? 154.161 118.404 134.437 1.00 66.84  ? 100 ARG   A O   1 
ATOM   564  C CB  . ARG   A 1 75  ? 152.735 117.167 137.160 1.00 75.26  ? 100 ARG   A CB  1 
ATOM   565  C CG  . ARG   A 1 75  ? 152.031 115.982 137.807 1.00 77.27  ? 100 ARG   A CG  1 
ATOM   566  C CD  . ARG   A 1 75  ? 150.534 116.201 137.927 1.00 74.16  ? 100 ARG   A CD  1 
ATOM   567  N NE  . ARG   A 1 75  ? 149.874 115.056 138.540 1.00 72.22  ? 100 ARG   A NE  1 
ATOM   568  C CZ  . ARG   A 1 75  ? 148.561 114.889 138.614 1.00 69.06  ? 100 ARG   A CZ  1 
ATOM   569  N NH1 . ARG   A 1 75  ? 147.717 115.777 138.114 1.00 71.42  ? 100 ARG   A NH1 1 
ATOM   570  N NH2 . ARG   A 1 75  ? 148.080 113.799 139.203 1.00 67.69  ? 100 ARG   A NH2 1 
ATOM   571  N N   . PHE   A 1 76  ? 152.760 119.799 135.522 1.00 64.53  ? 101 PHE   A N   1 
ATOM   572  C CA  . PHE   A 1 76  ? 153.452 121.034 135.153 1.00 62.67  ? 101 PHE   A CA  1 
ATOM   573  C C   . PHE   A 1 76  ? 153.656 121.896 136.393 1.00 63.27  ? 101 PHE   A C   1 
ATOM   574  O O   . PHE   A 1 76  ? 153.035 122.957 136.535 1.00 66.72  ? 101 PHE   A O   1 
ATOM   575  C CB  . PHE   A 1 76  ? 152.670 121.801 134.088 1.00 61.42  ? 101 PHE   A CB  1 
ATOM   576  C CG  . PHE   A 1 76  ? 152.372 121.000 132.857 1.00 58.47  ? 101 PHE   A CG  1 
ATOM   577  C CD1 . PHE   A 1 76  ? 153.393 120.538 132.052 1.00 60.28  ? 101 PHE   A CD1 1 
ATOM   578  C CD2 . PHE   A 1 76  ? 151.070 120.723 132.494 1.00 60.72  ? 101 PHE   A CD2 1 
ATOM   579  C CE1 . PHE   A 1 76  ? 153.122 119.807 130.923 1.00 60.55  ? 101 PHE   A CE1 1 
ATOM   580  C CE2 . PHE   A 1 76  ? 150.797 119.993 131.363 1.00 61.09  ? 101 PHE   A CE2 1 
ATOM   581  C CZ  . PHE   A 1 76  ? 151.823 119.534 130.578 1.00 62.76  ? 101 PHE   A CZ  1 
ATOM   582  N N   . PRO   A 1 77  ? 154.520 121.474 137.313 1.00 60.19  ? 102 PRO   A N   1 
ATOM   583  C CA  . PRO   A 1 77  ? 154.832 122.303 138.477 1.00 59.65  ? 102 PRO   A CA  1 
ATOM   584  C C   . PRO   A 1 77  ? 155.947 123.297 138.185 1.00 66.04  ? 102 PRO   A C   1 
ATOM   585  O O   . PRO   A 1 77  ? 156.759 123.120 137.274 1.00 70.97  ? 102 PRO   A O   1 
ATOM   586  C CB  . PRO   A 1 77  ? 155.281 121.271 139.516 1.00 63.44  ? 102 PRO   A CB  1 
ATOM   587  C CG  . PRO   A 1 77  ? 155.932 120.228 138.708 1.00 66.17  ? 102 PRO   A CG  1 
ATOM   588  C CD  . PRO   A 1 77  ? 155.142 120.142 137.427 1.00 63.44  ? 102 PRO   A CD  1 
ATOM   589  N N   . LEU   A 1 78  ? 155.969 124.365 138.985 1.00 65.77  ? 103 LEU   A N   1 
ATOM   590  C CA  . LEU   A 1 78  ? 156.994 125.390 138.814 1.00 66.34  ? 103 LEU   A CA  1 
ATOM   591  C C   . LEU   A 1 78  ? 158.382 124.820 139.071 1.00 72.15  ? 103 LEU   A C   1 
ATOM   592  O O   . LEU   A 1 78  ? 159.325 125.102 138.323 1.00 78.05  ? 103 LEU   A O   1 
ATOM   593  C CB  . LEU   A 1 78  ? 156.716 126.572 139.742 1.00 67.00  ? 103 LEU   A CB  1 
ATOM   594  C CG  . LEU   A 1 78  ? 157.122 127.959 139.235 1.00 72.91  ? 103 LEU   A CG  1 
ATOM   595  C CD1 . LEU   A 1 78  ? 156.720 129.015 140.243 1.00 73.99  ? 103 LEU   A CD1 1 
ATOM   596  C CD2 . LEU   A 1 78  ? 158.609 128.048 138.945 1.00 74.77  ? 103 LEU   A CD2 1 
ATOM   597  N N   . LEU   A 1 79  ? 158.522 124.016 140.120 1.00 78.84  ? 104 LEU   A N   1 
ATOM   598  C CA  . LEU   A 1 79  ? 159.762 123.326 140.451 1.00 81.76  ? 104 LEU   A CA  1 
ATOM   599  C C   . LEU   A 1 79  ? 159.545 121.831 140.277 1.00 83.19  ? 104 LEU   A C   1 
ATOM   600  O O   . LEU   A 1 79  ? 158.537 121.289 140.740 1.00 87.34  ? 104 LEU   A O   1 
ATOM   601  C CB  . LEU   A 1 79  ? 160.206 123.628 141.884 1.00 85.01  ? 104 LEU   A CB  1 
ATOM   602  C CG  . LEU   A 1 79  ? 160.462 125.094 142.255 1.00 89.65  ? 104 LEU   A CG  1 
ATOM   603  C CD1 . LEU   A 1 79  ? 159.174 125.863 142.559 1.00 86.00  ? 104 LEU   A CD1 1 
ATOM   604  C CD2 . LEU   A 1 79  ? 161.422 125.174 143.435 1.00 88.53  ? 104 LEU   A CD2 1 
ATOM   605  N N   . ASP   A 1 80  ? 160.491 121.168 139.611 1.00 83.42  ? 105 ASP   A N   1 
ATOM   606  C CA  . ASP   A 1 80  ? 160.364 119.735 139.377 1.00 90.08  ? 105 ASP   A CA  1 
ATOM   607  C C   . ASP   A 1 80  ? 160.398 118.931 140.669 1.00 88.53  ? 105 ASP   A C   1 
ATOM   608  O O   . ASP   A 1 80  ? 159.927 117.789 140.685 1.00 87.04  ? 105 ASP   A O   1 
ATOM   609  C CB  . ASP   A 1 80  ? 161.478 119.257 138.445 1.00 100.31 ? 105 ASP   A CB  1 
ATOM   610  C CG  . ASP   A 1 80  ? 161.456 119.960 137.101 1.00 101.12 ? 105 ASP   A CG  1 
ATOM   611  O OD1 . ASP   A 1 80  ? 160.359 120.350 136.649 1.00 96.40  ? 105 ASP   A OD1 1 
ATOM   612  O OD2 . ASP   A 1 80  ? 162.536 120.121 136.496 1.00 94.90  ? 105 ASP   A OD2 1 
ATOM   613  N N   . ALA   A 1 81  ? 160.947 119.491 141.748 1.00 89.52  ? 106 ALA   A N   1 
ATOM   614  C CA  . ALA   A 1 81  ? 161.012 118.756 143.006 1.00 90.94  ? 106 ALA   A CA  1 
ATOM   615  C C   . ALA   A 1 81  ? 159.622 118.513 143.582 1.00 89.45  ? 106 ALA   A C   1 
ATOM   616  O O   . ALA   A 1 81  ? 159.345 117.425 144.101 1.00 89.19  ? 106 ALA   A O   1 
ATOM   617  C CB  . ALA   A 1 81  ? 161.881 119.513 144.010 1.00 88.03  ? 106 ALA   A CB  1 
ATOM   618  N N   . LEU   A 1 82  ? 158.741 119.509 143.511 1.00 84.54  ? 107 LEU   A N   1 
ATOM   619  C CA  . LEU   A 1 82  ? 157.396 119.354 144.049 1.00 81.11  ? 107 LEU   A CA  1 
ATOM   620  C C   . LEU   A 1 82  ? 156.640 118.272 143.291 1.00 79.85  ? 107 LEU   A C   1 
ATOM   621  O O   . LEU   A 1 82  ? 156.701 118.199 142.061 1.00 81.64  ? 107 LEU   A O   1 
ATOM   622  C CB  . LEU   A 1 82  ? 156.630 120.675 143.965 1.00 77.77  ? 107 LEU   A CB  1 
ATOM   623  C CG  . LEU   A 1 82  ? 156.941 121.788 144.967 1.00 80.14  ? 107 LEU   A CG  1 
ATOM   624  C CD1 . LEU   A 1 82  ? 156.081 122.997 144.659 1.00 74.17  ? 107 LEU   A CD1 1 
ATOM   625  C CD2 . LEU   A 1 82  ? 156.720 121.335 146.402 1.00 78.27  ? 107 LEU   A CD2 1 
ATOM   626  N N   . ARG   A 1 83  ? 155.932 117.429 144.035 1.00 73.47  ? 108 ARG   A N   1 
ATOM   627  C CA  . ARG   A 1 83  ? 155.068 116.400 143.485 1.00 71.43  ? 108 ARG   A CA  1 
ATOM   628  C C   . ARG   A 1 83  ? 153.794 116.343 144.316 1.00 68.68  ? 108 ARG   A C   1 
ATOM   629  O O   . ARG   A 1 83  ? 153.832 116.645 145.514 1.00 70.01  ? 108 ARG   A O   1 
ATOM   630  C CB  . ARG   A 1 83  ? 155.750 115.025 143.489 1.00 78.84  ? 108 ARG   A CB  1 
ATOM   631  C CG  . ARG   A 1 83  ? 157.025 114.966 142.668 1.00 85.36  ? 108 ARG   A CG  1 
ATOM   632  C CD  . ARG   A 1 83  ? 157.603 113.561 142.639 1.00 93.04  ? 108 ARG   A CD  1 
ATOM   633  N NE  . ARG   A 1 83  ? 158.031 113.111 143.960 1.00 99.88  ? 108 ARG   A NE  1 
ATOM   634  C CZ  . ARG   A 1 83  ? 159.194 113.407 144.529 1.00 104.35 ? 108 ARG   A CZ  1 
ATOM   635  N NH1 . ARG   A 1 83  ? 160.088 114.180 143.931 1.00 101.72 ? 108 ARG   A NH1 1 
ATOM   636  N NH2 . ARG   A 1 83  ? 159.467 112.916 145.735 1.00 105.26 ? 108 ARG   A NH2 1 
ATOM   637  N N   . PRO   A 1 84  ? 152.657 115.971 143.723 1.00 68.63  ? 109 PRO   A N   1 
ATOM   638  C CA  . PRO   A 1 84  ? 151.442 115.831 144.530 1.00 63.03  ? 109 PRO   A CA  1 
ATOM   639  C C   . PRO   A 1 84  ? 151.564 114.716 145.555 1.00 69.73  ? 109 PRO   A C   1 
ATOM   640  O O   . PRO   A 1 84  ? 152.246 113.711 145.341 1.00 77.63  ? 109 PRO   A O   1 
ATOM   641  C CB  . PRO   A 1 84  ? 150.359 115.506 143.497 1.00 63.97  ? 109 PRO   A CB  1 
ATOM   642  C CG  . PRO   A 1 84  ? 150.885 115.974 142.221 1.00 69.45  ? 109 PRO   A CG  1 
ATOM   643  C CD  . PRO   A 1 84  ? 152.359 115.791 142.290 1.00 72.89  ? 109 PRO   A CD  1 
ATOM   644  N N   . LEU   A 1 85  ? 150.889 114.910 146.681 1.00 70.75  ? 110 LEU   A N   1 
ATOM   645  C CA  . LEU   A 1 85  ? 150.734 113.870 147.684 1.00 68.44  ? 110 LEU   A CA  1 
ATOM   646  C C   . LEU   A 1 85  ? 149.607 112.935 147.265 1.00 67.65  ? 110 LEU   A C   1 
ATOM   647  O O   . LEU   A 1 85  ? 148.911 113.189 146.281 1.00 73.82  ? 110 LEU   A O   1 
ATOM   648  C CB  . LEU   A 1 85  ? 150.445 114.506 149.041 1.00 66.83  ? 110 LEU   A CB  1 
ATOM   649  C CG  . LEU   A 1 85  ? 151.494 115.463 149.604 1.00 68.82  ? 110 LEU   A CG  1 
ATOM   650  C CD1 . LEU   A 1 85  ? 151.012 116.039 150.918 1.00 68.16  ? 110 LEU   A CD1 1 
ATOM   651  C CD2 . LEU   A 1 85  ? 152.835 114.771 149.789 1.00 72.09  ? 110 LEU   A CD2 1 
ATOM   652  N N   . PRO   A 1 86  ? 149.405 111.829 147.981 1.00 58.05  ? 111 PRO   A N   1 
ATOM   653  C CA  . PRO   A 1 86  ? 148.231 110.993 147.712 1.00 61.37  ? 111 PRO   A CA  1 
ATOM   654  C C   . PRO   A 1 86  ? 146.933 111.767 147.898 1.00 71.52  ? 111 PRO   A C   1 
ATOM   655  O O   . PRO   A 1 86  ? 146.898 112.881 148.424 1.00 77.51  ? 111 PRO   A O   1 
ATOM   656  C CB  . PRO   A 1 86  ? 148.369 109.857 148.725 1.00 59.50  ? 111 PRO   A CB  1 
ATOM   657  C CG  . PRO   A 1 86  ? 149.817 109.746 148.942 1.00 58.57  ? 111 PRO   A CG  1 
ATOM   658  C CD  . PRO   A 1 86  ? 150.358 111.140 148.869 1.00 58.22  ? 111 PRO   A CD  1 
ATOM   659  N N   . LEU   A 1 87  ? 145.843 111.143 147.448 1.00 70.79  ? 112 LEU   A N   1 
ATOM   660  C CA  . LEU   A 1 87  ? 144.560 111.836 147.368 1.00 69.71  ? 112 LEU   A CA  1 
ATOM   661  C C   . LEU   A 1 87  ? 144.059 112.259 148.743 1.00 73.23  ? 112 LEU   A C   1 
ATOM   662  O O   . LEU   A 1 87  ? 143.565 113.383 148.919 1.00 76.49  ? 112 LEU   A O   1 
ATOM   663  C CB  . LEU   A 1 87  ? 143.539 110.929 146.686 1.00 65.62  ? 112 LEU   A CB  1 
ATOM   664  C CG  . LEU   A 1 87  ? 142.241 111.575 146.209 1.00 71.17  ? 112 LEU   A CG  1 
ATOM   665  C CD1 . LEU   A 1 87  ? 142.501 112.557 145.081 1.00 73.07  ? 112 LEU   A CD1 1 
ATOM   666  C CD2 . LEU   A 1 87  ? 141.260 110.502 145.772 1.00 72.11  ? 112 LEU   A CD2 1 
ATOM   667  N N   . ASP   A 1 88  ? 144.174 111.371 149.730 1.00 67.93  ? 113 ASP   A N   1 
ATOM   668  C CA  . ASP   A 1 88  ? 143.609 111.653 151.043 1.00 68.75  ? 113 ASP   A CA  1 
ATOM   669  C C   . ASP   A 1 88  ? 144.318 112.823 151.714 1.00 67.55  ? 113 ASP   A C   1 
ATOM   670  O O   . ASP   A 1 88  ? 143.675 113.680 152.335 1.00 70.50  ? 113 ASP   A O   1 
ATOM   671  C CB  . ASP   A 1 88  ? 143.678 110.403 151.914 1.00 70.91  ? 113 ASP   A CB  1 
ATOM   672  C CG  . ASP   A 1 88  ? 143.028 109.205 151.261 1.00 77.76  ? 113 ASP   A CG  1 
ATOM   673  O OD1 . ASP   A 1 88  ? 141.979 109.383 150.610 1.00 80.41  ? 113 ASP   A OD1 1 
ATOM   674  O OD2 . ASP   A 1 88  ? 143.566 108.086 151.393 1.00 84.91  ? 113 ASP   A OD2 1 
ATOM   675  N N   . TRP   A 1 89  ? 145.644 112.880 151.599 1.00 59.28  ? 114 TRP   A N   1 
ATOM   676  C CA  . TRP   A 1 89  ? 146.367 114.000 152.182 1.00 65.53  ? 114 TRP   A CA  1 
ATOM   677  C C   . TRP   A 1 89  ? 146.036 115.302 151.466 1.00 66.85  ? 114 TRP   A C   1 
ATOM   678  O O   . TRP   A 1 89  ? 146.023 116.367 152.092 1.00 73.89  ? 114 TRP   A O   1 
ATOM   679  C CB  . TRP   A 1 89  ? 147.869 113.723 152.155 1.00 67.31  ? 114 TRP   A CB  1 
ATOM   680  C CG  . TRP   A 1 89  ? 148.251 112.472 152.889 1.00 65.28  ? 114 TRP   A CG  1 
ATOM   681  C CD1 . TRP   A 1 89  ? 148.443 111.237 152.350 1.00 67.61  ? 114 TRP   A CD1 1 
ATOM   682  C CD2 . TRP   A 1 89  ? 148.484 112.335 154.294 1.00 63.84  ? 114 TRP   A CD2 1 
ATOM   683  N NE1 . TRP   A 1 89  ? 148.782 110.340 153.329 1.00 66.29  ? 114 TRP   A NE1 1 
ATOM   684  C CE2 . TRP   A 1 89  ? 148.814 110.989 154.533 1.00 61.28  ? 114 TRP   A CE2 1 
ATOM   685  C CE3 . TRP   A 1 89  ? 148.446 113.221 155.374 1.00 68.74  ? 114 TRP   A CE3 1 
ATOM   686  C CZ2 . TRP   A 1 89  ? 149.103 110.506 155.803 1.00 63.83  ? 114 TRP   A CZ2 1 
ATOM   687  C CZ3 . TRP   A 1 89  ? 148.734 112.738 156.636 1.00 72.30  ? 114 TRP   A CZ3 1 
ATOM   688  C CH2 . TRP   A 1 89  ? 149.058 111.394 156.840 1.00 69.14  ? 114 TRP   A CH2 1 
ATOM   689  N N   . MET   A 1 90  ? 145.744 115.240 150.166 1.00 61.51  ? 115 MET   A N   1 
ATOM   690  C CA  . MET   A 1 90  ? 145.294 116.435 149.460 1.00 64.70  ? 115 MET   A CA  1 
ATOM   691  C C   . MET   A 1 90  ? 143.945 116.909 149.988 1.00 66.09  ? 115 MET   A C   1 
ATOM   692  O O   . MET   A 1 90  ? 143.721 118.118 150.149 1.00 68.77  ? 115 MET   A O   1 
ATOM   693  C CB  . MET   A 1 90  ? 145.219 116.156 147.962 1.00 63.14  ? 115 MET   A CB  1 
ATOM   694  C CG  . MET   A 1 90  ? 146.565 116.128 147.268 1.00 62.67  ? 115 MET   A CG  1 
ATOM   695  S SD  . MET   A 1 90  ? 147.220 117.778 146.990 1.00 80.58  ? 115 MET   A SD  1 
ATOM   696  C CE  . MET   A 1 90  ? 148.676 117.400 146.026 1.00 70.15  ? 115 MET   A CE  1 
ATOM   697  N N   . TYR   A 1 91  ? 143.032 115.975 150.261 1.00 63.12  ? 116 TYR   A N   1 
ATOM   698  C CA  . TYR   A 1 91  ? 141.759 116.364 150.860 1.00 60.11  ? 116 TYR   A CA  1 
ATOM   699  C C   . TYR   A 1 91  ? 141.971 116.977 152.239 1.00 63.31  ? 116 TYR   A C   1 
ATOM   700  O O   . TYR   A 1 91  ? 141.277 117.927 152.618 1.00 70.63  ? 116 TYR   A O   1 
ATOM   701  C CB  . TYR   A 1 91  ? 140.816 115.165 150.949 1.00 59.33  ? 116 TYR   A CB  1 
ATOM   702  C CG  . TYR   A 1 91  ? 139.895 114.980 149.761 1.00 55.95  ? 116 TYR   A CG  1 
ATOM   703  C CD1 . TYR   A 1 91  ? 138.954 115.939 149.426 1.00 61.70  ? 116 TYR   A CD1 1 
ATOM   704  C CD2 . TYR   A 1 91  ? 139.942 113.827 149.001 1.00 60.53  ? 116 TYR   A CD2 1 
ATOM   705  C CE1 . TYR   A 1 91  ? 138.112 115.766 148.354 1.00 65.28  ? 116 TYR   A CE1 1 
ATOM   706  C CE2 . TYR   A 1 91  ? 139.099 113.646 147.930 1.00 65.90  ? 116 TYR   A CE2 1 
ATOM   707  C CZ  . TYR   A 1 91  ? 138.186 114.617 147.613 1.00 66.44  ? 116 TYR   A CZ  1 
ATOM   708  O OH  . TYR   A 1 91  ? 137.343 114.441 146.545 1.00 70.01  ? 116 TYR   A OH  1 
ATOM   709  N N   . LEU   A 1 92  ? 142.928 116.449 153.002 1.00 60.58  ? 117 LEU   A N   1 
ATOM   710  C CA  . LEU   A 1 92  ? 143.256 117.051 154.293 1.00 59.88  ? 117 LEU   A CA  1 
ATOM   711  C C   . LEU   A 1 92  ? 143.778 118.474 154.121 1.00 62.69  ? 117 LEU   A C   1 
ATOM   712  O O   . LEU   A 1 92  ? 143.444 119.371 154.909 1.00 69.79  ? 117 LEU   A O   1 
ATOM   713  C CB  . LEU   A 1 92  ? 144.284 116.187 155.023 1.00 61.45  ? 117 LEU   A CB  1 
ATOM   714  C CG  . LEU   A 1 92  ? 144.822 116.693 156.363 1.00 62.29  ? 117 LEU   A CG  1 
ATOM   715  C CD1 . LEU   A 1 92  ? 143.697 116.929 157.353 1.00 65.80  ? 117 LEU   A CD1 1 
ATOM   716  C CD2 . LEU   A 1 92  ? 145.818 115.701 156.921 1.00 66.44  ? 117 LEU   A CD2 1 
ATOM   717  N N   . VAL   A 1 93  ? 144.612 118.693 153.104 1.00 59.80  ? 118 VAL   A N   1 
ATOM   718  C CA  . VAL   A 1 93  ? 145.144 120.027 152.838 1.00 56.30  ? 118 VAL   A CA  1 
ATOM   719  C C   . VAL   A 1 93  ? 144.008 120.996 152.529 1.00 60.76  ? 118 VAL   A C   1 
ATOM   720  O O   . VAL   A 1 93  ? 143.970 122.124 153.043 1.00 68.49  ? 118 VAL   A O   1 
ATOM   721  C CB  . VAL   A 1 93  ? 146.173 119.963 151.691 1.00 59.54  ? 118 VAL   A CB  1 
ATOM   722  C CG1 . VAL   A 1 93  ? 146.604 121.343 151.278 1.00 64.73  ? 118 VAL   A CG1 1 
ATOM   723  C CG2 . VAL   A 1 93  ? 147.405 119.163 152.106 1.00 62.31  ? 118 VAL   A CG2 1 
ATOM   724  N N   . TYR   A 1 94  ? 143.060 120.572 151.693 1.00 57.47  ? 119 TYR   A N   1 
ATOM   725  C CA  . TYR   A 1 94  ? 141.926 121.440 151.386 1.00 57.73  ? 119 TYR   A CA  1 
ATOM   726  C C   . TYR   A 1 94  ? 141.036 121.665 152.606 1.00 61.25  ? 119 TYR   A C   1 
ATOM   727  O O   . TYR   A 1 94  ? 140.448 122.745 152.755 1.00 68.47  ? 119 TYR   A O   1 
ATOM   728  C CB  . TYR   A 1 94  ? 141.114 120.863 150.230 1.00 60.00  ? 119 TYR   A CB  1 
ATOM   729  C CG  . TYR   A 1 94  ? 141.636 121.257 148.868 1.00 64.58  ? 119 TYR   A CG  1 
ATOM   730  C CD1 . TYR   A 1 94  ? 142.713 120.600 148.297 1.00 68.46  ? 119 TYR   A CD1 1 
ATOM   731  C CD2 . TYR   A 1 94  ? 141.048 122.283 148.153 1.00 61.67  ? 119 TYR   A CD2 1 
ATOM   732  C CE1 . TYR   A 1 94  ? 143.187 120.958 147.058 1.00 65.68  ? 119 TYR   A CE1 1 
ATOM   733  C CE2 . TYR   A 1 94  ? 141.517 122.646 146.914 1.00 64.23  ? 119 TYR   A CE2 1 
ATOM   734  C CZ  . TYR   A 1 94  ? 142.586 121.980 146.371 1.00 66.44  ? 119 TYR   A CZ  1 
ATOM   735  O OH  . TYR   A 1 94  ? 143.059 122.338 145.132 1.00 73.20  ? 119 TYR   A OH  1 
ATOM   736  N N   . THR   A 1 95  ? 140.924 120.671 153.488 1.00 60.78  ? 120 THR   A N   1 
ATOM   737  C CA  . THR   A 1 95  ? 140.190 120.877 154.733 1.00 61.43  ? 120 THR   A CA  1 
ATOM   738  C C   . THR   A 1 95  ? 140.851 121.955 155.583 1.00 65.72  ? 120 THR   A C   1 
ATOM   739  O O   . THR   A 1 95  ? 140.167 122.800 156.177 1.00 70.44  ? 120 THR   A O   1 
ATOM   740  C CB  . THR   A 1 95  ? 140.103 119.569 155.516 1.00 65.48  ? 120 THR   A CB  1 
ATOM   741  O OG1 . THR   A 1 95  ? 139.427 118.581 154.730 1.00 71.62  ? 120 THR   A OG1 1 
ATOM   742  C CG2 . THR   A 1 95  ? 139.356 119.774 156.822 1.00 65.44  ? 120 THR   A CG2 1 
ATOM   743  N N   . ILE   A 1 96  ? 142.182 121.929 155.666 1.00 62.65  ? 121 ILE   A N   1 
ATOM   744  C CA  . ILE   A 1 96  ? 142.894 122.965 156.412 1.00 57.69  ? 121 ILE   A CA  1 
ATOM   745  C C   . ILE   A 1 96  ? 142.675 124.328 155.766 1.00 63.17  ? 121 ILE   A C   1 
ATOM   746  O O   . ILE   A 1 96  ? 142.549 125.345 156.461 1.00 66.91  ? 121 ILE   A O   1 
ATOM   747  C CB  . ILE   A 1 96  ? 144.389 122.610 156.527 1.00 56.27  ? 121 ILE   A CB  1 
ATOM   748  C CG1 . ILE   A 1 96  ? 144.568 121.464 157.528 1.00 58.48  ? 121 ILE   A CG1 1 
ATOM   749  C CG2 . ILE   A 1 96  ? 145.211 123.829 156.953 1.00 62.58  ? 121 ILE   A CG2 1 
ATOM   750  C CD1 . ILE   A 1 96  ? 145.921 120.782 157.473 1.00 59.77  ? 121 ILE   A CD1 1 
ATOM   751  N N   . MET   A 1 97  ? 142.629 124.375 154.431 1.00 60.96  ? 122 MET   A N   1 
ATOM   752  C CA  . MET   A 1 97  ? 142.310 125.632 153.752 1.00 61.53  ? 122 MET   A CA  1 
ATOM   753  C C   . MET   A 1 97  ? 140.941 126.151 154.168 1.00 65.93  ? 122 MET   A C   1 
ATOM   754  O O   . MET   A 1 97  ? 140.777 127.345 154.454 1.00 70.13  ? 122 MET   A O   1 
ATOM   755  C CB  . MET   A 1 97  ? 142.336 125.450 152.237 1.00 65.53  ? 122 MET   A CB  1 
ATOM   756  C CG  . MET   A 1 97  ? 143.705 125.458 151.618 1.00 68.99  ? 122 MET   A CG  1 
ATOM   757  S SD  . MET   A 1 97  ? 143.666 125.241 149.830 1.00 81.38  ? 122 MET   A SD  1 
ATOM   758  C CE  . MET   A 1 97  ? 142.869 126.755 149.317 1.00 64.50  ? 122 MET   A CE  1 
ATOM   759  N N   . PHE   A 1 98  ? 139.943 125.268 154.193 1.00 64.98  ? 123 PHE   A N   1 
ATOM   760  C CA  . PHE   A 1 98  ? 138.593 125.682 154.563 1.00 64.66  ? 123 PHE   A CA  1 
ATOM   761  C C   . PHE   A 1 98  ? 138.548 126.190 155.999 1.00 67.02  ? 123 PHE   A C   1 
ATOM   762  O O   . PHE   A 1 98  ? 137.906 127.211 156.290 1.00 70.75  ? 123 PHE   A O   1 
ATOM   763  C CB  . PHE   A 1 98  ? 137.629 124.511 154.370 1.00 63.07  ? 123 PHE   A CB  1 
ATOM   764  C CG  . PHE   A 1 98  ? 136.201 124.840 154.678 1.00 64.05  ? 123 PHE   A CG  1 
ATOM   765  C CD1 . PHE   A 1 98  ? 135.400 125.446 153.733 1.00 63.84  ? 123 PHE   A CD1 1 
ATOM   766  C CD2 . PHE   A 1 98  ? 135.655 124.529 155.910 1.00 72.06  ? 123 PHE   A CD2 1 
ATOM   767  C CE1 . PHE   A 1 98  ? 134.085 125.744 154.010 1.00 72.85  ? 123 PHE   A CE1 1 
ATOM   768  C CE2 . PHE   A 1 98  ? 134.340 124.825 156.194 1.00 79.61  ? 123 PHE   A CE2 1 
ATOM   769  C CZ  . PHE   A 1 98  ? 133.553 125.434 155.243 1.00 79.98  ? 123 PHE   A CZ  1 
ATOM   770  N N   . LEU   A 1 99  ? 139.227 125.491 156.912 1.00 65.60  ? 124 LEU   A N   1 
ATOM   771  C CA  . LEU   A 1 99  ? 139.257 125.933 158.304 1.00 63.57  ? 124 LEU   A CA  1 
ATOM   772  C C   . LEU   A 1 99  ? 139.933 127.291 158.438 1.00 61.34  ? 124 LEU   A C   1 
ATOM   773  O O   . LEU   A 1 99  ? 139.467 128.153 159.193 1.00 65.73  ? 124 LEU   A O   1 
ATOM   774  C CB  . LEU   A 1 99  ? 139.965 124.898 159.176 1.00 59.93  ? 124 LEU   A CB  1 
ATOM   775  C CG  . LEU   A 1 99  ? 139.058 123.883 159.873 1.00 66.84  ? 124 LEU   A CG  1 
ATOM   776  C CD1 . LEU   A 1 99  ? 138.255 123.056 158.878 1.00 66.86  ? 124 LEU   A CD1 1 
ATOM   777  C CD2 . LEU   A 1 99  ? 139.887 122.980 160.766 1.00 66.50  ? 124 LEU   A CD2 1 
ATOM   778  N N   . GLY   A 1 100 ? 141.032 127.503 157.713 1.00 61.13  ? 125 GLY   A N   1 
ATOM   779  C CA  . GLY   A 1 100 ? 141.693 128.797 157.758 1.00 63.52  ? 125 GLY   A CA  1 
ATOM   780  C C   . GLY   A 1 100 ? 140.816 129.914 157.231 1.00 61.83  ? 125 GLY   A C   1 
ATOM   781  O O   . GLY   A 1 100 ? 140.793 131.016 157.786 1.00 64.67  ? 125 GLY   A O   1 
ATOM   782  N N   . ALA   A 1 101 ? 140.087 129.647 156.147 1.00 60.83  ? 126 ALA   A N   1 
ATOM   783  C CA  . ALA   A 1 101 ? 139.186 130.655 155.603 1.00 62.57  ? 126 ALA   A CA  1 
ATOM   784  C C   . ALA   A 1 101 ? 138.085 131.001 156.597 1.00 65.67  ? 126 ALA   A C   1 
ATOM   785  O O   . ALA   A 1 101 ? 137.748 132.179 156.777 1.00 69.21  ? 126 ALA   A O   1 
ATOM   786  C CB  . ALA   A 1 101 ? 138.591 130.165 154.285 1.00 65.56  ? 126 ALA   A CB  1 
ATOM   787  N N   . LEU   A 1 102 ? 137.510 129.989 157.255 1.00 67.95  ? 127 LEU   A N   1 
ATOM   788  C CA  . LEU   A 1 102 ? 136.500 130.263 158.277 1.00 63.26  ? 127 LEU   A CA  1 
ATOM   789  C C   . LEU   A 1 102 ? 137.081 131.087 159.419 1.00 61.76  ? 127 LEU   A C   1 
ATOM   790  O O   . LEU   A 1 102 ? 136.435 132.022 159.913 1.00 65.33  ? 127 LEU   A O   1 
ATOM   791  C CB  . LEU   A 1 102 ? 135.913 128.960 158.820 1.00 65.22  ? 127 LEU   A CB  1 
ATOM   792  C CG  . LEU   A 1 102 ? 134.631 128.429 158.179 1.00 68.00  ? 127 LEU   A CG  1 
ATOM   793  C CD1 . LEU   A 1 102 ? 134.302 127.059 158.742 1.00 71.44  ? 127 LEU   A CD1 1 
ATOM   794  C CD2 . LEU   A 1 102 ? 133.465 129.380 158.392 1.00 68.44  ? 127 LEU   A CD2 1 
ATOM   795  N N   . GLY   A 1 103 ? 138.292 130.747 159.862 1.00 61.76  ? 128 GLY   A N   1 
ATOM   796  C CA  . GLY   A 1 103 ? 138.920 131.510 160.928 1.00 61.90  ? 128 GLY   A CA  1 
ATOM   797  C C   . GLY   A 1 103 ? 139.146 132.960 160.550 1.00 63.55  ? 128 GLY   A C   1 
ATOM   798  O O   . GLY   A 1 103 ? 138.938 133.863 161.363 1.00 70.56  ? 128 GLY   A O   1 
ATOM   799  N N   . MET   A 1 104 ? 139.579 133.203 159.312 1.00 63.30  ? 129 MET   A N   1 
ATOM   800  C CA  . MET   A 1 104 ? 139.726 134.578 158.844 1.00 63.36  ? 129 MET   A CA  1 
ATOM   801  C C   . MET   A 1 104 ? 138.382 135.290 158.807 1.00 65.08  ? 129 MET   A C   1 
ATOM   802  O O   . MET   A 1 104 ? 138.292 136.478 159.134 1.00 70.42  ? 129 MET   A O   1 
ATOM   803  C CB  . MET   A 1 104 ? 140.374 134.603 157.461 1.00 69.52  ? 129 MET   A CB  1 
ATOM   804  C CG  . MET   A 1 104 ? 141.854 134.278 157.465 1.00 73.79  ? 129 MET   A CG  1 
ATOM   805  S SD  . MET   A 1 104 ? 142.592 134.327 155.820 1.00 90.02  ? 129 MET   A SD  1 
ATOM   806  C CE  . MET   A 1 104 ? 142.454 136.066 155.427 1.00 68.42  ? 129 MET   A CE  1 
ATOM   807  N N   . MET   A 1 105 ? 137.328 134.582 158.398 1.00 65.23  ? 130 MET   A N   1 
ATOM   808  C CA  . MET   A 1 105 ? 136.005 135.196 158.329 1.00 60.48  ? 130 MET   A CA  1 
ATOM   809  C C   . MET   A 1 105 ? 135.531 135.631 159.709 1.00 61.29  ? 130 MET   A C   1 
ATOM   810  O O   . MET   A 1 105 ? 135.087 136.769 159.894 1.00 63.92  ? 130 MET   A O   1 
ATOM   811  C CB  . MET   A 1 105 ? 135.009 134.217 157.708 1.00 65.52  ? 130 MET   A CB  1 
ATOM   812  C CG  . MET   A 1 105 ? 133.653 134.822 157.375 1.00 66.27  ? 130 MET   A CG  1 
ATOM   813  S SD  . MET   A 1 105 ? 132.457 133.603 156.809 1.00 87.99  ? 130 MET   A SD  1 
ATOM   814  C CE  . MET   A 1 105 ? 132.103 132.739 158.336 1.00 73.76  ? 130 MET   A CE  1 
ATOM   815  N N   . LEU   A 1 106 ? 135.623 134.740 160.694 1.00 61.27  ? 131 LEU   A N   1 
ATOM   816  C CA  . LEU   A 1 106 ? 135.136 135.034 162.035 1.00 60.75  ? 131 LEU   A CA  1 
ATOM   817  C C   . LEU   A 1 106 ? 136.176 135.703 162.922 1.00 64.32  ? 131 LEU   A C   1 
ATOM   818  O O   . LEU   A 1 106 ? 135.835 136.125 164.032 1.00 70.96  ? 131 LEU   A O   1 
ATOM   819  C CB  . LEU   A 1 106 ? 134.657 133.749 162.717 1.00 63.02  ? 131 LEU   A CB  1 
ATOM   820  C CG  . LEU   A 1 106 ? 133.555 132.958 162.013 1.00 64.70  ? 131 LEU   A CG  1 
ATOM   821  C CD1 . LEU   A 1 106 ? 133.265 131.678 162.774 1.00 66.91  ? 131 LEU   A CD1 1 
ATOM   822  C CD2 . LEU   A 1 106 ? 132.290 133.785 161.862 1.00 68.33  ? 131 LEU   A CD2 1 
ATOM   823  N N   . GLY   A 1 107 ? 137.421 135.814 162.474 1.00 65.50  ? 132 GLY   A N   1 
ATOM   824  C CA  . GLY   A 1 107 ? 138.447 136.445 163.282 1.00 63.30  ? 132 GLY   A CA  1 
ATOM   825  C C   . GLY   A 1 107 ? 138.767 135.698 164.557 1.00 67.20  ? 132 GLY   A C   1 
ATOM   826  O O   . GLY   A 1 107 ? 138.993 136.330 165.596 1.00 76.68  ? 132 GLY   A O   1 
ATOM   827  N N   . LEU   A 1 108 ? 138.797 134.368 164.502 1.00 65.47  ? 133 LEU   A N   1 
ATOM   828  C CA  . LEU   A 1 108 ? 139.087 133.514 165.650 1.00 68.60  ? 133 LEU   A CA  1 
ATOM   829  C C   . LEU   A 1 108 ? 140.467 132.901 165.445 1.00 67.96  ? 133 LEU   A C   1 
ATOM   830  O O   . LEU   A 1 108 ? 140.669 132.122 164.509 1.00 69.25  ? 133 LEU   A O   1 
ATOM   831  C CB  . LEU   A 1 108 ? 138.015 132.438 165.800 1.00 67.39  ? 133 LEU   A CB  1 
ATOM   832  C CG  . LEU   A 1 108 ? 138.198 131.390 166.897 1.00 72.82  ? 133 LEU   A CG  1 
ATOM   833  C CD1 . LEU   A 1 108 ? 138.369 132.041 168.261 1.00 74.23  ? 133 LEU   A CD1 1 
ATOM   834  C CD2 . LEU   A 1 108 ? 137.016 130.436 166.901 1.00 70.04  ? 133 LEU   A CD2 1 
ATOM   835  N N   . CYS   A 1 109 ? 141.411 133.253 166.320 1.00 63.49  ? 134 CYS   A N   1 
ATOM   836  C CA  . CYS   A 1 109 ? 142.807 132.841 166.184 1.00 63.11  ? 134 CYS   A CA  1 
ATOM   837  C C   . CYS   A 1 109 ? 143.357 133.301 164.832 1.00 65.88  ? 134 CYS   A C   1 
ATOM   838  O O   . CYS   A 1 109 ? 143.714 132.501 163.964 1.00 71.41  ? 134 CYS   A O   1 
ATOM   839  C CB  . CYS   A 1 109 ? 142.952 131.328 166.365 1.00 68.74  ? 134 CYS   A CB  1 
ATOM   840  S SG  . CYS   A 1 109 ? 142.284 130.707 167.920 1.00 94.88  ? 134 CYS   A SG  1 
ATOM   841  N N   . TYR   A 1 110 ? 143.401 134.626 164.672 1.00 61.21  ? 135 TYR   A N   1 
ATOM   842  C CA  . TYR   A 1 110 ? 143.531 135.228 163.349 1.00 61.82  ? 135 TYR   A CA  1 
ATOM   843  C C   . TYR   A 1 110 ? 144.846 134.854 162.675 1.00 67.73  ? 135 TYR   A C   1 
ATOM   844  O O   . TYR   A 1 110 ? 144.865 134.490 161.495 1.00 76.08  ? 135 TYR   A O   1 
ATOM   845  C CB  . TYR   A 1 110 ? 143.403 136.744 163.460 1.00 64.60  ? 135 TYR   A CB  1 
ATOM   846  C CG  . TYR   A 1 110 ? 143.424 137.456 162.133 1.00 64.38  ? 135 TYR   A CG  1 
ATOM   847  C CD1 . TYR   A 1 110 ? 142.315 137.462 161.311 1.00 67.22  ? 135 TYR   A CD1 1 
ATOM   848  C CD2 . TYR   A 1 110 ? 144.553 138.135 161.710 1.00 66.90  ? 135 TYR   A CD2 1 
ATOM   849  C CE1 . TYR   A 1 110 ? 142.330 138.115 160.102 1.00 71.39  ? 135 TYR   A CE1 1 
ATOM   850  C CE2 . TYR   A 1 110 ? 144.577 138.791 160.503 1.00 70.21  ? 135 TYR   A CE2 1 
ATOM   851  C CZ  . TYR   A 1 110 ? 143.464 138.779 159.703 1.00 74.41  ? 135 TYR   A CZ  1 
ATOM   852  O OH  . TYR   A 1 110 ? 143.485 139.435 158.495 1.00 77.76  ? 135 TYR   A OH  1 
ATOM   853  N N   . ARG   A 1 111 ? 145.962 134.951 163.400 1.00 60.57  ? 136 ARG   A N   1 
ATOM   854  C CA  . ARG   A 1 111 ? 147.257 134.695 162.773 1.00 62.72  ? 136 ARG   A CA  1 
ATOM   855  C C   . ARG   A 1 111 ? 147.397 133.233 162.366 1.00 66.80  ? 136 ARG   A C   1 
ATOM   856  O O   . ARG   A 1 111 ? 147.885 132.927 161.268 1.00 69.10  ? 136 ARG   A O   1 
ATOM   857  C CB  . ARG   A 1 111 ? 148.392 135.110 163.711 1.00 59.15  ? 136 ARG   A CB  1 
ATOM   858  C CG  . ARG   A 1 111 ? 149.010 136.466 163.380 1.00 65.40  ? 136 ARG   A CG  1 
ATOM   859  C CD  . ARG   A 1 111 ? 147.989 137.600 163.370 1.00 72.55  ? 136 ARG   A CD  1 
ATOM   860  N NE  . ARG   A 1 111 ? 148.605 138.888 163.065 1.00 75.20  ? 136 ARG   A NE  1 
ATOM   861  C CZ  . ARG   A 1 111 ? 149.155 139.707 163.953 1.00 77.52  ? 136 ARG   A CZ  1 
ATOM   862  N NH1 . ARG   A 1 111 ? 149.204 139.411 165.243 1.00 75.89  ? 136 ARG   A NH1 1 
ATOM   863  N NH2 . ARG   A 1 111 ? 149.675 140.857 163.535 1.00 76.86  ? 136 ARG   A NH2 1 
ATOM   864  N N   . ILE   A 1 112 ? 146.965 132.314 163.232 1.00 61.96  ? 137 ILE   A N   1 
ATOM   865  C CA  . ILE   A 1 112 ? 147.048 130.894 162.907 1.00 61.35  ? 137 ILE   A CA  1 
ATOM   866  C C   . ILE   A 1 112 ? 146.159 130.572 161.713 1.00 61.08  ? 137 ILE   A C   1 
ATOM   867  O O   . ILE   A 1 112 ? 146.555 129.822 160.813 1.00 65.40  ? 137 ILE   A O   1 
ATOM   868  C CB  . ILE   A 1 112 ? 146.684 130.043 164.137 1.00 63.02  ? 137 ILE   A CB  1 
ATOM   869  C CG1 . ILE   A 1 112 ? 147.758 130.187 165.221 1.00 64.87  ? 137 ILE   A CG1 1 
ATOM   870  C CG2 . ILE   A 1 112 ? 146.516 128.575 163.741 1.00 65.47  ? 137 ILE   A CG2 1 
ATOM   871  C CD1 . ILE   A 1 112 ? 147.326 129.712 166.598 1.00 67.10  ? 137 ILE   A CD1 1 
ATOM   872  N N   . SER   A 1 113 ? 144.947 131.128 161.686 1.00 57.07  ? 138 SER   A N   1 
ATOM   873  C CA  . SER   A 1 113 ? 144.050 130.890 160.559 1.00 58.17  ? 138 SER   A CA  1 
ATOM   874  C C   . SER   A 1 113 ? 144.632 131.445 159.266 1.00 62.70  ? 138 SER   A C   1 
ATOM   875  O O   . SER   A 1 113 ? 144.538 130.808 158.208 1.00 67.79  ? 138 SER   A O   1 
ATOM   876  C CB  . SER   A 1 113 ? 142.684 131.510 160.841 1.00 60.65  ? 138 SER   A CB  1 
ATOM   877  O OG  . SER   A 1 113 ? 142.139 131.010 162.046 1.00 65.79  ? 138 SER   A OG  1 
ATOM   878  N N   . CYS   A 1 114 ? 145.240 132.631 159.330 1.00 60.92  ? 139 CYS   A N   1 
ATOM   879  C CA  . CYS   A 1 114 ? 145.849 133.216 158.143 1.00 62.14  ? 139 CYS   A CA  1 
ATOM   880  C C   . CYS   A 1 114 ? 146.987 132.349 157.621 1.00 65.08  ? 139 CYS   A C   1 
ATOM   881  O O   . CYS   A 1 114 ? 147.110 132.143 156.410 1.00 70.62  ? 139 CYS   A O   1 
ATOM   882  C CB  . CYS   A 1 114 ? 146.347 134.626 158.453 1.00 63.24  ? 139 CYS   A CB  1 
ATOM   883  S SG  . CYS   A 1 114 ? 145.048 135.875 158.514 1.00 81.43  ? 139 CYS   A SG  1 
ATOM   884  N N   . VAL   A 1 115 ? 147.829 131.831 158.517 1.00 61.53  ? 140 VAL   A N   1 
ATOM   885  C CA  . VAL   A 1 115 ? 148.923 130.960 158.085 1.00 57.41  ? 140 VAL   A CA  1 
ATOM   886  C C   . VAL   A 1 115 ? 148.376 129.670 157.482 1.00 58.17  ? 140 VAL   A C   1 
ATOM   887  O O   . VAL   A 1 115 ? 148.870 129.183 156.451 1.00 62.09  ? 140 VAL   A O   1 
ATOM   888  C CB  . VAL   A 1 115 ? 149.871 130.682 159.266 1.00 55.61  ? 140 VAL   A CB  1 
ATOM   889  C CG1 . VAL   A 1 115 ? 150.856 129.576 158.927 1.00 57.11  ? 140 VAL   A CG1 1 
ATOM   890  C CG2 . VAL   A 1 115 ? 150.614 131.950 159.651 1.00 57.75  ? 140 VAL   A CG2 1 
ATOM   891  N N   . LEU   A 1 116 ? 147.357 129.088 158.123 1.00 56.33  ? 141 LEU   A N   1 
ATOM   892  C CA  . LEU   A 1 116 ? 146.777 127.842 157.634 1.00 59.63  ? 141 LEU   A CA  1 
ATOM   893  C C   . LEU   A 1 116 ? 146.107 128.026 156.282 1.00 62.03  ? 141 LEU   A C   1 
ATOM   894  O O   . LEU   A 1 116 ? 145.997 127.066 155.513 1.00 68.09  ? 141 LEU   A O   1 
ATOM   895  C CB  . LEU   A 1 116 ? 145.765 127.294 158.642 1.00 60.22  ? 141 LEU   A CB  1 
ATOM   896  C CG  . LEU   A 1 116 ? 146.278 126.694 159.953 1.00 63.48  ? 141 LEU   A CG  1 
ATOM   897  C CD1 . LEU   A 1 116 ? 145.104 126.263 160.809 1.00 60.42  ? 141 LEU   A CD1 1 
ATOM   898  C CD2 . LEU   A 1 116 ? 147.216 125.520 159.717 1.00 65.15  ? 141 LEU   A CD2 1 
ATOM   899  N N   . PHE   A 1 117 ? 145.606 129.225 155.993 1.00 58.04  ? 142 PHE   A N   1 
ATOM   900  C CA  . PHE   A 1 117 ? 145.113 129.501 154.650 1.00 58.91  ? 142 PHE   A CA  1 
ATOM   901  C C   . PHE   A 1 117 ? 146.246 129.765 153.668 1.00 58.93  ? 142 PHE   A C   1 
ATOM   902  O O   . PHE   A 1 117 ? 146.160 129.357 152.506 1.00 65.95  ? 142 PHE   A O   1 
ATOM   903  C CB  . PHE   A 1 117 ? 144.163 130.695 154.666 1.00 59.53  ? 142 PHE   A CB  1 
ATOM   904  C CG  . PHE   A 1 117 ? 143.589 131.026 153.320 1.00 59.09  ? 142 PHE   A CG  1 
ATOM   905  C CD1 . PHE   A 1 117 ? 142.524 130.312 152.817 1.00 62.61  ? 142 PHE   A CD1 1 
ATOM   906  C CD2 . PHE   A 1 117 ? 144.112 132.054 152.564 1.00 60.74  ? 142 PHE   A CD2 1 
ATOM   907  C CE1 . PHE   A 1 117 ? 141.995 130.611 151.587 1.00 65.36  ? 142 PHE   A CE1 1 
ATOM   908  C CE2 . PHE   A 1 117 ? 143.586 132.356 151.333 1.00 61.07  ? 142 PHE   A CE2 1 
ATOM   909  C CZ  . PHE   A 1 117 ? 142.526 131.634 150.845 1.00 61.61  ? 142 PHE   A CZ  1 
ATOM   910  N N   . LEU   A 1 118 ? 147.304 130.443 154.111 1.00 55.41  ? 143 LEU   A N   1 
ATOM   911  C CA  . LEU   A 1 118 ? 148.326 130.916 153.187 1.00 53.28  ? 143 LEU   A CA  1 
ATOM   912  C C   . LEU   A 1 118 ? 149.183 129.772 152.664 1.00 56.56  ? 143 LEU   A C   1 
ATOM   913  O O   . LEU   A 1 118 ? 149.419 129.668 151.455 1.00 62.31  ? 143 LEU   A O   1 
ATOM   914  C CB  . LEU   A 1 118 ? 149.199 131.962 153.883 1.00 55.21  ? 143 LEU   A CB  1 
ATOM   915  C CG  . LEU   A 1 118 ? 150.287 132.656 153.065 1.00 57.66  ? 143 LEU   A CG  1 
ATOM   916  C CD1 . LEU   A 1 118 ? 149.674 133.530 151.986 1.00 61.03  ? 143 LEU   A CD1 1 
ATOM   917  C CD2 . LEU   A 1 118 ? 151.183 133.474 153.972 1.00 56.31  ? 143 LEU   A CD2 1 
ATOM   918  N N   . LEU   A 1 119 ? 149.667 128.902 153.560 1.00 55.33  ? 144 LEU   A N   1 
ATOM   919  C CA  . LEU   A 1 119 ? 150.664 127.919 153.131 1.00 52.15  ? 144 LEU   A CA  1 
ATOM   920  C C   . LEU   A 1 119 ? 150.063 126.873 152.196 1.00 58.20  ? 144 LEU   A C   1 
ATOM   921  O O   . LEU   A 1 119 ? 150.629 126.634 151.112 1.00 63.00  ? 144 LEU   A O   1 
ATOM   922  C CB  . LEU   A 1 119 ? 151.347 127.299 154.352 1.00 49.92  ? 144 LEU   A CB  1 
ATOM   923  C CG  . LEU   A 1 119 ? 152.559 128.046 154.909 1.00 57.79  ? 144 LEU   A CG  1 
ATOM   924  C CD1 . LEU   A 1 119 ? 152.221 129.489 155.238 1.00 60.24  ? 144 LEU   A CD1 1 
ATOM   925  C CD2 . LEU   A 1 119 ? 153.089 127.331 156.137 1.00 59.99  ? 144 LEU   A CD2 1 
ATOM   926  N N   . PRO   A 1 120 ? 148.950 126.217 152.535 1.00 54.25  ? 145 PRO   A N   1 
ATOM   927  C CA  . PRO   A 1 120 ? 148.283 125.338 151.564 1.00 51.88  ? 145 PRO   A CA  1 
ATOM   928  C C   . PRO   A 1 120 ? 147.925 125.997 150.245 1.00 56.69  ? 145 PRO   A C   1 
ATOM   929  O O   . PRO   A 1 120 ? 148.037 125.348 149.194 1.00 64.18  ? 145 PRO   A O   1 
ATOM   930  C CB  . PRO   A 1 120 ? 147.022 124.923 152.320 1.00 52.09  ? 145 PRO   A CB  1 
ATOM   931  C CG  . PRO   A 1 120 ? 147.452 124.846 153.708 1.00 55.52  ? 145 PRO   A CG  1 
ATOM   932  C CD  . PRO   A 1 120 ? 148.456 125.958 153.898 1.00 58.00  ? 145 PRO   A CD  1 
ATOM   933  N N   . TYR   A 1 121 ? 147.472 127.252 150.266 1.00 53.75  ? 146 TYR   A N   1 
ATOM   934  C CA  . TYR   A 1 121 ? 147.069 127.908 149.028 1.00 53.04  ? 146 TYR   A CA  1 
ATOM   935  C C   . TYR   A 1 121 ? 148.241 128.009 148.066 1.00 57.95  ? 146 TYR   A C   1 
ATOM   936  O O   . TYR   A 1 121 ? 148.109 127.706 146.876 1.00 63.83  ? 146 TYR   A O   1 
ATOM   937  C CB  . TYR   A 1 121 ? 146.496 129.293 149.324 1.00 53.70  ? 146 TYR   A CB  1 
ATOM   938  C CG  . TYR   A 1 121 ? 145.875 129.974 148.123 1.00 52.04  ? 146 TYR   A CG  1 
ATOM   939  C CD1 . TYR   A 1 121 ? 146.636 130.749 147.265 1.00 53.19  ? 146 TYR   A CD1 1 
ATOM   940  C CD2 . TYR   A 1 121 ? 144.525 129.851 147.858 1.00 55.02  ? 146 TYR   A CD2 1 
ATOM   941  C CE1 . TYR   A 1 121 ? 146.074 131.365 146.178 1.00 54.27  ? 146 TYR   A CE1 1 
ATOM   942  C CE2 . TYR   A 1 121 ? 143.956 130.467 146.773 1.00 56.12  ? 146 TYR   A CE2 1 
ATOM   943  C CZ  . TYR   A 1 121 ? 144.734 131.223 145.936 1.00 57.74  ? 146 TYR   A CZ  1 
ATOM   944  O OH  . TYR   A 1 121 ? 144.167 131.843 144.848 1.00 66.38  ? 146 TYR   A OH  1 
ATOM   945  N N   . TRP   A 1 122 ? 149.408 128.411 148.568 1.00 55.09  ? 147 TRP   A N   1 
ATOM   946  C CA  . TRP   A 1 122 ? 150.564 128.536 147.692 1.00 56.49  ? 147 TRP   A CA  1 
ATOM   947  C C   . TRP   A 1 122 ? 151.144 127.178 147.326 1.00 57.22  ? 147 TRP   A C   1 
ATOM   948  O O   . TRP   A 1 122 ? 151.711 127.029 146.238 1.00 61.15  ? 147 TRP   A O   1 
ATOM   949  C CB  . TRP   A 1 122 ? 151.619 129.428 148.340 1.00 57.07  ? 147 TRP   A CB  1 
ATOM   950  C CG  . TRP   A 1 122 ? 151.248 130.872 148.267 1.00 57.18  ? 147 TRP   A CG  1 
ATOM   951  C CD1 . TRP   A 1 122 ? 150.681 131.621 149.251 1.00 58.81  ? 147 TRP   A CD1 1 
ATOM   952  C CD2 . TRP   A 1 122 ? 151.392 131.737 147.138 1.00 54.38  ? 147 TRP   A CD2 1 
ATOM   953  N NE1 . TRP   A 1 122 ? 150.472 132.901 148.812 1.00 60.04  ? 147 TRP   A NE1 1 
ATOM   954  C CE2 . TRP   A 1 122 ? 150.901 132.998 147.515 1.00 54.98  ? 147 TRP   A CE2 1 
ATOM   955  C CE3 . TRP   A 1 122 ? 151.895 131.569 145.846 1.00 60.17  ? 147 TRP   A CE3 1 
ATOM   956  C CZ2 . TRP   A 1 122 ? 150.898 134.085 146.650 1.00 58.11  ? 147 TRP   A CZ2 1 
ATOM   957  C CZ3 . TRP   A 1 122 ? 151.891 132.650 144.990 1.00 61.40  ? 147 TRP   A CZ3 1 
ATOM   958  C CH2 . TRP   A 1 122 ? 151.394 133.891 145.394 1.00 56.95  ? 147 TRP   A CH2 1 
ATOM   959  N N   . TYR   A 1 123 ? 151.006 126.175 148.198 1.00 53.40  ? 148 TYR   A N   1 
ATOM   960  C CA  . TYR   A 1 123 ? 151.388 124.821 147.805 1.00 56.07  ? 148 TYR   A CA  1 
ATOM   961  C C   . TYR   A 1 123 ? 150.583 124.365 146.595 1.00 61.00  ? 148 TYR   A C   1 
ATOM   962  O O   . TYR   A 1 123 ? 151.140 123.839 145.625 1.00 65.54  ? 148 TYR   A O   1 
ATOM   963  C CB  . TYR   A 1 123 ? 151.196 123.848 148.966 1.00 57.85  ? 148 TYR   A CB  1 
ATOM   964  C CG  . TYR   A 1 123 ? 151.468 122.407 148.590 1.00 60.13  ? 148 TYR   A CG  1 
ATOM   965  C CD1 . TYR   A 1 123 ? 152.764 121.923 148.522 1.00 66.63  ? 148 TYR   A CD1 1 
ATOM   966  C CD2 . TYR   A 1 123 ? 150.431 121.533 148.305 1.00 60.29  ? 148 TYR   A CD2 1 
ATOM   967  C CE1 . TYR   A 1 123 ? 153.019 120.612 148.179 1.00 67.58  ? 148 TYR   A CE1 1 
ATOM   968  C CE2 . TYR   A 1 123 ? 150.679 120.221 147.960 1.00 65.13  ? 148 TYR   A CE2 1 
ATOM   969  C CZ  . TYR   A 1 123 ? 151.974 119.767 147.899 1.00 67.41  ? 148 TYR   A CZ  1 
ATOM   970  O OH  . TYR   A 1 123 ? 152.228 118.460 147.558 1.00 74.95  ? 148 TYR   A OH  1 
ATOM   971  N N   . VAL   A 1 124 ? 149.264 124.556 146.638 1.00 60.51  ? 149 VAL   A N   1 
ATOM   972  C CA  . VAL   A 1 124 ? 148.423 124.180 145.504 1.00 56.23  ? 149 VAL   A CA  1 
ATOM   973  C C   . VAL   A 1 124 ? 148.746 125.041 144.289 1.00 55.55  ? 149 VAL   A C   1 
ATOM   974  O O   . VAL   A 1 124 ? 148.784 124.550 143.154 1.00 62.39  ? 149 VAL   A O   1 
ATOM   975  C CB  . VAL   A 1 124 ? 146.933 124.274 145.887 1.00 56.22  ? 149 VAL   A CB  1 
ATOM   976  C CG1 . VAL   A 1 124 ? 146.054 124.061 144.666 1.00 59.22  ? 149 VAL   A CG1 1 
ATOM   977  C CG2 . VAL   A 1 124 ? 146.594 123.260 146.964 1.00 61.23  ? 149 VAL   A CG2 1 
ATOM   978  N N   . PHE   A 1 125 ? 148.970 126.339 144.504 1.00 52.21  ? 150 PHE   A N   1 
ATOM   979  C CA  . PHE   A 1 125 ? 149.205 127.261 143.397 1.00 54.25  ? 150 PHE   A CA  1 
ATOM   980  C C   . PHE   A 1 125 ? 150.477 126.911 142.634 1.00 56.38  ? 150 PHE   A C   1 
ATOM   981  O O   . PHE   A 1 125 ? 150.490 126.928 141.399 1.00 59.28  ? 150 PHE   A O   1 
ATOM   982  C CB  . PHE   A 1 125 ? 149.276 128.689 143.936 1.00 57.24  ? 150 PHE   A CB  1 
ATOM   983  C CG  . PHE   A 1 125 ? 149.268 129.748 142.875 1.00 55.27  ? 150 PHE   A CG  1 
ATOM   984  C CD1 . PHE   A 1 125 ? 148.095 130.103 142.243 1.00 55.98  ? 150 PHE   A CD1 1 
ATOM   985  C CD2 . PHE   A 1 125 ? 150.429 130.410 142.533 1.00 55.40  ? 150 PHE   A CD2 1 
ATOM   986  C CE1 . PHE   A 1 125 ? 148.084 131.082 141.277 1.00 59.14  ? 150 PHE   A CE1 1 
ATOM   987  C CE2 . PHE   A 1 125 ? 150.421 131.391 141.569 1.00 56.70  ? 150 PHE   A CE2 1 
ATOM   988  C CZ  . PHE   A 1 125 ? 149.248 131.728 140.941 1.00 59.70  ? 150 PHE   A CZ  1 
ATOM   989  N N   . LEU   A 1 126 ? 151.555 126.588 143.348 1.00 59.11  ? 151 LEU   A N   1 
ATOM   990  C CA  . LEU   A 1 126 ? 152.808 126.250 142.685 1.00 58.02  ? 151 LEU   A CA  1 
ATOM   991  C C   . LEU   A 1 126 ? 152.805 124.847 142.092 1.00 59.60  ? 151 LEU   A C   1 
ATOM   992  O O   . LEU   A 1 126 ? 153.685 124.531 141.286 1.00 66.48  ? 151 LEU   A O   1 
ATOM   993  C CB  . LEU   A 1 126 ? 153.978 126.379 143.663 1.00 59.37  ? 151 LEU   A CB  1 
ATOM   994  C CG  . LEU   A 1 126 ? 154.242 127.752 144.288 1.00 59.96  ? 151 LEU   A CG  1 
ATOM   995  C CD1 . LEU   A 1 126 ? 155.398 127.659 145.263 1.00 63.43  ? 151 LEU   A CD1 1 
ATOM   996  C CD2 . LEU   A 1 126 ? 154.526 128.806 143.235 1.00 61.19  ? 151 LEU   A CD2 1 
ATOM   997  N N   . LEU   A 1 127 ? 151.846 124.000 142.468 1.00 59.63  ? 152 LEU   A N   1 
ATOM   998  C CA  . LEU   A 1 127 ? 151.849 122.619 142.000 1.00 55.34  ? 152 LEU   A CA  1 
ATOM   999  C C   . LEU   A 1 127 ? 151.446 122.487 140.537 1.00 62.34  ? 152 LEU   A C   1 
ATOM   1000 O O   . LEU   A 1 127 ? 151.700 121.439 139.936 1.00 72.83  ? 152 LEU   A O   1 
ATOM   1001 C CB  . LEU   A 1 127 ? 150.916 121.766 142.861 1.00 57.58  ? 152 LEU   A CB  1 
ATOM   1002 C CG  . LEU   A 1 127 ? 151.512 120.480 143.423 1.00 62.83  ? 152 LEU   A CG  1 
ATOM   1003 C CD1 . LEU   A 1 127 ? 150.510 119.801 144.332 1.00 65.59  ? 152 LEU   A CD1 1 
ATOM   1004 C CD2 . LEU   A 1 127 ? 151.942 119.546 142.308 1.00 69.02  ? 152 LEU   A CD2 1 
ATOM   1005 N N   . ASP   A 1 128 ? 150.825 123.509 139.951 1.00 60.15  ? 153 ASP   A N   1 
ATOM   1006 C CA  . ASP   A 1 128 ? 150.374 123.434 138.567 1.00 61.47  ? 153 ASP   A CA  1 
ATOM   1007 C C   . ASP   A 1 128 ? 150.338 124.830 137.968 1.00 62.68  ? 153 ASP   A C   1 
ATOM   1008 O O   . ASP   A 1 128 ? 149.631 125.705 138.475 1.00 62.94  ? 153 ASP   A O   1 
ATOM   1009 C CB  . ASP   A 1 128 ? 148.990 122.789 138.476 1.00 64.48  ? 153 ASP   A CB  1 
ATOM   1010 C CG  . ASP   A 1 128 ? 148.490 122.683 137.051 1.00 74.53  ? 153 ASP   A CG  1 
ATOM   1011 O OD1 . ASP   A 1 128 ? 149.037 121.859 136.289 1.00 74.78  ? 153 ASP   A OD1 1 
ATOM   1012 O OD2 . ASP   A 1 128 ? 147.552 123.426 136.690 1.00 79.60  ? 153 ASP   A OD2 1 
ATOM   1013 N N   . LYS   A 1 129 ? 151.091 125.030 136.887 1.00 62.61  ? 154 LYS   A N   1 
ATOM   1014 C CA  . LYS   A 1 129 ? 151.142 126.315 136.204 1.00 60.54  ? 154 LYS   A CA  1 
ATOM   1015 C C   . LYS   A 1 129 ? 149.982 126.532 135.244 1.00 62.15  ? 154 LYS   A C   1 
ATOM   1016 O O   . LYS   A 1 129 ? 149.786 127.662 134.786 1.00 65.11  ? 154 LYS   A O   1 
ATOM   1017 C CB  . LYS   A 1 129 ? 152.455 126.450 135.427 1.00 60.51  ? 154 LYS   A CB  1 
ATOM   1018 C CG  . LYS   A 1 129 ? 153.698 126.420 136.291 1.00 62.72  ? 154 LYS   A CG  1 
ATOM   1019 C CD  . LYS   A 1 129 ? 154.957 126.668 135.479 1.00 65.18  ? 154 LYS   A CD  1 
ATOM   1020 C CE  . LYS   A 1 129 ? 155.295 125.499 134.580 1.00 67.98  ? 154 LYS   A CE  1 
ATOM   1021 N NZ  . LYS   A 1 129 ? 156.652 125.640 133.996 1.00 68.32  ? 154 LYS   A NZ  1 
ATOM   1022 N N   . THR   A 1 130 ? 149.213 125.491 134.923 1.00 61.46  ? 155 THR   A N   1 
ATOM   1023 C CA  . THR   A 1 130 ? 148.098 125.629 133.998 1.00 60.41  ? 155 THR   A CA  1 
ATOM   1024 C C   . THR   A 1 130 ? 146.849 126.198 134.653 1.00 65.09  ? 155 THR   A C   1 
ATOM   1025 O O   . THR   A 1 130 ? 145.913 126.567 133.935 1.00 75.14  ? 155 THR   A O   1 
ATOM   1026 C CB  . THR   A 1 130 ? 147.757 124.275 133.375 1.00 63.98  ? 155 THR   A CB  1 
ATOM   1027 O OG1 . THR   A 1 130 ? 147.270 123.386 134.388 1.00 72.18  ? 155 THR   A OG1 1 
ATOM   1028 C CG2 . THR   A 1 130 ? 148.977 123.666 132.724 1.00 64.46  ? 155 THR   A CG2 1 
ATOM   1029 N N   . SER   A 1 131 ? 146.811 126.281 135.983 1.00 65.08  ? 156 SER   A N   1 
ATOM   1030 C CA  . SER   A 1 131 ? 145.689 126.851 136.716 1.00 63.99  ? 156 SER   A CA  1 
ATOM   1031 C C   . SER   A 1 131 ? 146.004 128.244 137.244 1.00 66.13  ? 156 SER   A C   1 
ATOM   1032 O O   . SER   A 1 131 ? 145.374 128.693 138.206 1.00 69.96  ? 156 SER   A O   1 
ATOM   1033 C CB  . SER   A 1 131 ? 145.293 125.930 137.869 1.00 64.18  ? 156 SER   A CB  1 
ATOM   1034 O OG  . SER   A 1 131 ? 146.333 125.842 138.826 1.00 66.48  ? 156 SER   A OG  1 
ATOM   1035 N N   . TRP   A 1 132 ? 146.964 128.934 136.634 1.00 61.86  ? 157 TRP   A N   1 
ATOM   1036 C CA  . TRP   A 1 132 ? 147.353 130.266 137.064 1.00 59.98  ? 157 TRP   A CA  1 
ATOM   1037 C C   . TRP   A 1 132 ? 146.507 131.305 136.347 1.00 64.78  ? 157 TRP   A C   1 
ATOM   1038 O O   . TRP   A 1 132 ? 146.335 131.246 135.126 1.00 68.44  ? 157 TRP   A O   1 
ATOM   1039 C CB  . TRP   A 1 132 ? 148.835 130.520 136.789 1.00 55.88  ? 157 TRP   A CB  1 
ATOM   1040 C CG  . TRP   A 1 132 ? 149.765 129.832 137.735 1.00 55.13  ? 157 TRP   A CG  1 
ATOM   1041 C CD1 . TRP   A 1 132 ? 149.483 128.770 138.538 1.00 59.08  ? 157 TRP   A CD1 1 
ATOM   1042 C CD2 . TRP   A 1 132 ? 151.133 130.164 137.977 1.00 52.67  ? 157 TRP   A CD2 1 
ATOM   1043 N NE1 . TRP   A 1 132 ? 150.591 128.417 139.263 1.00 59.86  ? 157 TRP   A NE1 1 
ATOM   1044 C CE2 . TRP   A 1 132 ? 151.619 129.260 138.936 1.00 56.07  ? 157 TRP   A CE2 1 
ATOM   1045 C CE3 . TRP   A 1 132 ? 151.996 131.139 137.474 1.00 54.42  ? 157 TRP   A CE3 1 
ATOM   1046 C CZ2 . TRP   A 1 132 ? 152.925 129.301 139.402 1.00 60.61  ? 157 TRP   A CZ2 1 
ATOM   1047 C CZ3 . TRP   A 1 132 ? 153.290 131.177 137.939 1.00 57.60  ? 157 TRP   A CZ3 1 
ATOM   1048 C CH2 . TRP   A 1 132 ? 153.743 130.265 138.892 1.00 62.27  ? 157 TRP   A CH2 1 
ATOM   1049 N N   . ASN   A 1 133 ? 145.981 132.251 137.116 1.00 61.47  ? 158 ASN   A N   1 
ATOM   1050 C CA  . ASN   A 1 133 ? 145.271 133.396 136.577 1.00 54.94  ? 158 ASN   A CA  1 
ATOM   1051 C C   . ASN   A 1 133 ? 145.457 134.548 137.548 1.00 61.66  ? 158 ASN   A C   1 
ATOM   1052 O O   . ASN   A 1 133 ? 145.858 134.355 138.698 1.00 68.24  ? 158 ASN   A O   1 
ATOM   1053 C CB  . ASN   A 1 133 ? 143.788 133.091 136.350 1.00 56.19  ? 158 ASN   A CB  1 
ATOM   1054 C CG  . ASN   A 1 133 ? 143.228 132.139 137.379 1.00 61.88  ? 158 ASN   A CG  1 
ATOM   1055 O OD1 . ASN   A 1 133 ? 142.933 132.531 138.507 1.00 67.53  ? 158 ASN   A OD1 1 
ATOM   1056 N ND2 . ASN   A 1 133 ? 143.073 130.878 136.996 1.00 63.42  ? 158 ASN   A ND2 1 
ATOM   1057 N N   . ASN   A 1 134 ? 145.178 135.758 137.065 1.00 59.70  ? 159 ASN   A N   1 
ATOM   1058 C CA  . ASN   A 1 134 ? 145.450 136.950 137.861 1.00 59.43  ? 159 ASN   A CA  1 
ATOM   1059 C C   . ASN   A 1 134 ? 144.620 136.973 139.137 1.00 59.73  ? 159 ASN   A C   1 
ATOM   1060 O O   . ASN   A 1 134 ? 145.111 137.382 140.198 1.00 64.87  ? 159 ASN   A O   1 
ATOM   1061 C CB  . ASN   A 1 134 ? 145.189 138.200 137.029 1.00 61.65  ? 159 ASN   A CB  1 
ATOM   1062 C CG  . ASN   A 1 134 ? 146.063 138.267 135.799 1.00 66.17  ? 159 ASN   A CG  1 
ATOM   1063 O OD1 . ASN   A 1 134 ? 147.236 138.627 135.877 1.00 66.86  ? 159 ASN   A OD1 1 
ATOM   1064 N ND2 . ASN   A 1 134 ? 145.495 137.922 134.652 1.00 70.72  ? 159 ASN   A ND2 1 
ATOM   1065 N N   . HIS   A 1 135 ? 143.361 136.544 139.062 1.00 53.86  ? 160 HIS   A N   1 
ATOM   1066 C CA  . HIS   A 1 135 ? 142.509 136.609 140.239 1.00 58.23  ? 160 HIS   A CA  1 
ATOM   1067 C C   . HIS   A 1 135 ? 142.895 135.601 141.311 1.00 63.03  ? 160 HIS   A C   1 
ATOM   1068 O O   . HIS   A 1 135 ? 142.426 135.736 142.444 1.00 69.71  ? 160 HIS   A O   1 
ATOM   1069 C CB  . HIS   A 1 135 ? 141.039 136.427 139.847 1.00 63.02  ? 160 HIS   A CB  1 
ATOM   1070 C CG  . HIS   A 1 135 ? 140.715 135.091 139.255 1.00 61.83  ? 160 HIS   A CG  1 
ATOM   1071 N ND1 . HIS   A 1 135 ? 140.506 134.910 137.906 1.00 60.42  ? 160 HIS   A ND1 1 
ATOM   1072 C CD2 . HIS   A 1 135 ? 140.525 133.880 139.829 1.00 65.12  ? 160 HIS   A CD2 1 
ATOM   1073 C CE1 . HIS   A 1 135 ? 140.222 133.642 137.672 1.00 60.97  ? 160 HIS   A CE1 1 
ATOM   1074 N NE2 . HIS   A 1 135 ? 140.230 132.995 138.822 1.00 67.85  ? 160 HIS   A NE2 1 
ATOM   1075 N N   . SER   A 1 136 ? 143.732 134.611 140.999 1.00 55.56  ? 161 SER   A N   1 
ATOM   1076 C CA  . SER   A 1 136 ? 144.254 133.707 142.017 1.00 52.60  ? 161 SER   A CA  1 
ATOM   1077 C C   . SER   A 1 136 ? 145.508 134.269 142.671 1.00 52.89  ? 161 SER   A C   1 
ATOM   1078 O O   . SER   A 1 136 ? 145.676 134.176 143.896 1.00 62.82  ? 161 SER   A O   1 
ATOM   1079 C CB  . SER   A 1 136 ? 144.556 132.343 141.402 1.00 55.28  ? 161 SER   A CB  1 
ATOM   1080 O OG  . SER   A 1 136 ? 143.390 131.772 140.840 1.00 68.14  ? 161 SER   A OG  1 
ATOM   1081 N N   . TYR   A 1 137 ? 146.386 134.863 141.864 1.00 47.33  ? 162 TYR   A N   1 
ATOM   1082 C CA  . TYR   A 1 137 ? 147.556 135.539 142.405 1.00 50.11  ? 162 TYR   A CA  1 
ATOM   1083 C C   . TYR   A 1 137 ? 147.143 136.682 143.320 1.00 58.21  ? 162 TYR   A C   1 
ATOM   1084 O O   . TYR   A 1 137 ? 147.772 136.913 144.359 1.00 63.57  ? 162 TYR   A O   1 
ATOM   1085 C CB  . TYR   A 1 137 ? 148.428 136.040 141.253 1.00 54.58  ? 162 TYR   A CB  1 
ATOM   1086 C CG  . TYR   A 1 137 ? 149.739 136.682 141.650 1.00 57.88  ? 162 TYR   A CG  1 
ATOM   1087 C CD1 . TYR   A 1 137 ? 150.631 136.035 142.489 1.00 61.49  ? 162 TYR   A CD1 1 
ATOM   1088 C CD2 . TYR   A 1 137 ? 150.101 137.921 141.147 1.00 57.05  ? 162 TYR   A CD2 1 
ATOM   1089 C CE1 . TYR   A 1 137 ? 151.832 136.619 142.837 1.00 62.83  ? 162 TYR   A CE1 1 
ATOM   1090 C CE2 . TYR   A 1 137 ? 151.298 138.507 141.487 1.00 54.83  ? 162 TYR   A CE2 1 
ATOM   1091 C CZ  . TYR   A 1 137 ? 152.159 137.855 142.331 1.00 60.65  ? 162 TYR   A CZ  1 
ATOM   1092 O OH  . TYR   A 1 137 ? 153.354 138.444 142.670 1.00 68.68  ? 162 TYR   A OH  1 
ATOM   1093 N N   . LEU   A 1 138 ? 146.079 137.404 142.958 1.00 56.75  ? 163 LEU   A N   1 
ATOM   1094 C CA  . LEU   A 1 138 ? 145.608 138.489 143.812 1.00 54.94  ? 163 LEU   A CA  1 
ATOM   1095 C C   . LEU   A 1 138 ? 145.114 137.962 145.152 1.00 57.77  ? 163 LEU   A C   1 
ATOM   1096 O O   . LEU   A 1 138 ? 145.379 138.566 146.198 1.00 62.59  ? 163 LEU   A O   1 
ATOM   1097 C CB  . LEU   A 1 138 ? 144.503 139.275 143.108 1.00 54.82  ? 163 LEU   A CB  1 
ATOM   1098 C CG  . LEU   A 1 138 ? 143.951 140.505 143.834 1.00 59.95  ? 163 LEU   A CG  1 
ATOM   1099 C CD1 . LEU   A 1 138 ? 145.034 141.539 144.078 1.00 63.54  ? 163 LEU   A CD1 1 
ATOM   1100 C CD2 . LEU   A 1 138 ? 142.816 141.111 143.039 1.00 63.79  ? 163 LEU   A CD2 1 
ATOM   1101 N N   . TYR   A 1 139 ? 144.384 136.844 145.143 1.00 56.39  ? 164 TYR   A N   1 
ATOM   1102 C CA  . TYR   A 1 139 ? 143.920 136.267 146.400 1.00 52.48  ? 164 TYR   A CA  1 
ATOM   1103 C C   . TYR   A 1 139 ? 145.097 135.838 147.261 1.00 52.49  ? 164 TYR   A C   1 
ATOM   1104 O O   . TYR   A 1 139 ? 145.102 136.060 148.478 1.00 59.94  ? 164 TYR   A O   1 
ATOM   1105 C CB  . TYR   A 1 139 ? 143.005 135.069 146.146 1.00 50.05  ? 164 TYR   A CB  1 
ATOM   1106 C CG  . TYR   A 1 139 ? 141.761 135.332 145.323 1.00 54.21  ? 164 TYR   A CG  1 
ATOM   1107 C CD1 . TYR   A 1 139 ? 141.268 136.615 145.129 1.00 64.39  ? 164 TYR   A CD1 1 
ATOM   1108 C CD2 . TYR   A 1 139 ? 141.074 134.279 144.744 1.00 55.35  ? 164 TYR   A CD2 1 
ATOM   1109 C CE1 . TYR   A 1 139 ? 140.138 136.833 144.375 1.00 69.84  ? 164 TYR   A CE1 1 
ATOM   1110 C CE2 . TYR   A 1 139 ? 139.946 134.490 143.994 1.00 61.65  ? 164 TYR   A CE2 1 
ATOM   1111 C CZ  . TYR   A 1 139 ? 139.481 135.766 143.812 1.00 72.67  ? 164 TYR   A CZ  1 
ATOM   1112 O OH  . TYR   A 1 139 ? 138.349 135.974 143.060 1.00 77.96  ? 164 TYR   A OH  1 
ATOM   1113 N N   . GLY   A 1 140 ? 146.101 135.214 146.645 1.00 49.45  ? 165 GLY   A N   1 
ATOM   1114 C CA  . GLY   A 1 140 ? 147.283 134.826 147.396 1.00 51.48  ? 165 GLY   A CA  1 
ATOM   1115 C C   . GLY   A 1 140 ? 147.996 136.017 148.007 1.00 56.06  ? 165 GLY   A C   1 
ATOM   1116 O O   . GLY   A 1 140 ? 148.411 135.977 149.167 1.00 61.85  ? 165 GLY   A O   1 
ATOM   1117 N N   . LEU   A 1 141 ? 148.136 137.099 147.239 1.00 55.18  ? 166 LEU   A N   1 
ATOM   1118 C CA  . LEU   A 1 141 ? 148.795 138.292 147.759 1.00 56.27  ? 166 LEU   A CA  1 
ATOM   1119 C C   . LEU   A 1 141 ? 148.000 138.916 148.898 1.00 61.39  ? 166 LEU   A C   1 
ATOM   1120 O O   . LEU   A 1 141 ? 148.581 139.373 149.888 1.00 64.71  ? 166 LEU   A O   1 
ATOM   1121 C CB  . LEU   A 1 141 ? 148.998 139.314 146.643 1.00 55.80  ? 166 LEU   A CB  1 
ATOM   1122 C CG  . LEU   A 1 141 ? 150.007 138.999 145.540 1.00 61.08  ? 166 LEU   A CG  1 
ATOM   1123 C CD1 . LEU   A 1 141 ? 149.958 140.106 144.510 1.00 62.24  ? 166 LEU   A CD1 1 
ATOM   1124 C CD2 . LEU   A 1 141 ? 151.414 138.837 146.084 1.00 61.02  ? 166 LEU   A CD2 1 
ATOM   1125 N N   . LEU   A 1 142 ? 146.673 138.967 148.769 1.00 61.73  ? 167 LEU   A N   1 
ATOM   1126 C CA  . LEU   A 1 142 ? 145.862 139.534 149.841 1.00 58.18  ? 167 LEU   A CA  1 
ATOM   1127 C C   . LEU   A 1 142 ? 145.960 138.692 151.106 1.00 56.70  ? 167 LEU   A C   1 
ATOM   1128 O O   . LEU   A 1 142 ? 146.045 139.235 152.213 1.00 66.43  ? 167 LEU   A O   1 
ATOM   1129 C CB  . LEU   A 1 142 ? 144.408 139.666 149.392 1.00 59.22  ? 167 LEU   A CB  1 
ATOM   1130 C CG  . LEU   A 1 142 ? 144.109 140.721 148.324 1.00 61.22  ? 167 LEU   A CG  1 
ATOM   1131 C CD1 . LEU   A 1 142 ? 142.677 140.593 147.844 1.00 62.81  ? 167 LEU   A CD1 1 
ATOM   1132 C CD2 . LEU   A 1 142 ? 144.362 142.123 148.841 1.00 66.26  ? 167 LEU   A CD2 1 
ATOM   1133 N N   . ALA   A 1 143 ? 145.953 137.365 150.964 1.00 54.90  ? 168 ALA   A N   1 
ATOM   1134 C CA  . ALA   A 1 143 ? 146.129 136.502 152.127 1.00 55.64  ? 168 ALA   A CA  1 
ATOM   1135 C C   . ALA   A 1 143 ? 147.499 136.710 152.758 1.00 55.01  ? 168 ALA   A C   1 
ATOM   1136 O O   . ALA   A 1 143 ? 147.635 136.693 153.985 1.00 60.64  ? 168 ALA   A O   1 
ATOM   1137 C CB  . ALA   A 1 143 ? 145.937 135.041 151.730 1.00 58.23  ? 168 ALA   A CB  1 
ATOM   1138 N N   . PHE   A 1 144 ? 148.529 136.898 151.931 1.00 55.89  ? 169 PHE   A N   1 
ATOM   1139 C CA  . PHE   A 1 144 ? 149.862 137.173 152.456 1.00 54.08  ? 169 PHE   A CA  1 
ATOM   1140 C C   . PHE   A 1 144 ? 149.893 138.483 153.230 1.00 58.37  ? 169 PHE   A C   1 
ATOM   1141 O O   . PHE   A 1 144 ? 150.501 138.566 154.303 1.00 62.69  ? 169 PHE   A O   1 
ATOM   1142 C CB  . PHE   A 1 144 ? 150.868 137.206 151.307 1.00 55.37  ? 169 PHE   A CB  1 
ATOM   1143 C CG  . PHE   A 1 144 ? 152.244 137.624 151.715 1.00 56.17  ? 169 PHE   A CG  1 
ATOM   1144 C CD1 . PHE   A 1 144 ? 153.013 136.819 152.527 1.00 58.15  ? 169 PHE   A CD1 1 
ATOM   1145 C CD2 . PHE   A 1 144 ? 152.779 138.816 151.270 1.00 61.50  ? 169 PHE   A CD2 1 
ATOM   1146 C CE1 . PHE   A 1 144 ? 154.278 137.201 152.898 1.00 57.48  ? 169 PHE   A CE1 1 
ATOM   1147 C CE2 . PHE   A 1 144 ? 154.044 139.199 151.637 1.00 64.18  ? 169 PHE   A CE2 1 
ATOM   1148 C CZ  . PHE   A 1 144 ? 154.795 138.390 152.451 1.00 61.34  ? 169 PHE   A CZ  1 
ATOM   1149 N N   . GLN   A 1 145 ? 149.248 139.519 152.697 1.00 60.23  ? 170 GLN   A N   1 
ATOM   1150 C CA  . GLN   A 1 145 ? 149.231 140.816 153.365 1.00 59.77  ? 170 GLN   A CA  1 
ATOM   1151 C C   . GLN   A 1 145 ? 148.486 140.744 154.690 1.00 64.61  ? 170 GLN   A C   1 
ATOM   1152 O O   . GLN   A 1 145 ? 148.974 141.225 155.719 1.00 71.16  ? 170 GLN   A O   1 
ATOM   1153 C CB  . GLN   A 1 145 ? 148.592 141.864 152.457 1.00 60.72  ? 170 GLN   A CB  1 
ATOM   1154 C CG  . GLN   A 1 145 ? 149.407 142.208 151.235 1.00 65.68  ? 170 GLN   A CG  1 
ATOM   1155 C CD  . GLN   A 1 145 ? 148.623 143.016 150.232 1.00 71.86  ? 170 GLN   A CD  1 
ATOM   1156 O OE1 . GLN   A 1 145 ? 147.771 143.822 150.599 1.00 71.89  ? 170 GLN   A OE1 1 
ATOM   1157 N NE2 . GLN   A 1 145 ? 148.897 142.798 148.954 1.00 71.23  ? 170 GLN   A NE2 1 
ATOM   1158 N N   . LEU   A 1 146 ? 147.294 140.144 154.685 1.00 65.47  ? 171 LEU   A N   1 
ATOM   1159 C CA  . LEU   A 1 146 ? 146.443 140.143 155.871 1.00 63.28  ? 171 LEU   A CA  1 
ATOM   1160 C C   . LEU   A 1 146 ? 147.022 139.337 157.025 1.00 64.50  ? 171 LEU   A C   1 
ATOM   1161 O O   . LEU   A 1 146 ? 146.529 139.470 158.149 1.00 68.97  ? 171 LEU   A O   1 
ATOM   1162 C CB  . LEU   A 1 146 ? 145.051 139.611 155.522 1.00 62.06  ? 171 LEU   A CB  1 
ATOM   1163 C CG  . LEU   A 1 146 ? 143.999 140.661 155.152 1.00 65.25  ? 171 LEU   A CG  1 
ATOM   1164 C CD1 . LEU   A 1 146 ? 144.376 141.448 153.908 1.00 66.91  ? 171 LEU   A CD1 1 
ATOM   1165 C CD2 . LEU   A 1 146 ? 142.654 139.994 154.958 1.00 66.97  ? 171 LEU   A CD2 1 
ATOM   1166 N N   . THR   A 1 147 ? 148.042 138.509 156.787 1.00 59.98  ? 172 THR   A N   1 
ATOM   1167 C CA  . THR   A 1 147 ? 148.652 137.761 157.880 1.00 64.12  ? 172 THR   A CA  1 
ATOM   1168 C C   . THR   A 1 147 ? 149.290 138.684 158.910 1.00 69.40  ? 172 THR   A C   1 
ATOM   1169 O O   . THR   A 1 147 ? 149.348 138.338 160.096 1.00 73.88  ? 172 THR   A O   1 
ATOM   1170 C CB  . THR   A 1 147 ? 149.699 136.791 157.332 1.00 68.41  ? 172 THR   A CB  1 
ATOM   1171 O OG1 . THR   A 1 147 ? 149.067 135.836 156.472 1.00 67.73  ? 172 THR   A OG1 1 
ATOM   1172 C CG2 . THR   A 1 147 ? 150.402 136.059 158.460 1.00 67.74  ? 172 THR   A CG2 1 
ATOM   1173 N N   . PHE   A 1 148 ? 149.758 139.859 158.488 1.00 69.47  ? 173 PHE   A N   1 
ATOM   1174 C CA  . PHE   A 1 148 ? 150.482 140.771 159.364 1.00 66.57  ? 173 PHE   A CA  1 
ATOM   1175 C C   . PHE   A 1 148 ? 149.622 141.904 159.901 1.00 69.97  ? 173 PHE   A C   1 
ATOM   1176 O O   . PHE   A 1 148 ? 149.962 142.478 160.941 1.00 74.61  ? 173 PHE   A O   1 
ATOM   1177 C CB  . PHE   A 1 148 ? 151.677 141.375 158.622 1.00 63.39  ? 173 PHE   A CB  1 
ATOM   1178 C CG  . PHE   A 1 148 ? 152.601 140.354 158.029 1.00 68.37  ? 173 PHE   A CG  1 
ATOM   1179 C CD1 . PHE   A 1 148 ? 153.635 139.823 158.774 1.00 71.65  ? 173 PHE   A CD1 1 
ATOM   1180 C CD2 . PHE   A 1 148 ? 152.441 139.933 156.724 1.00 70.51  ? 173 PHE   A CD2 1 
ATOM   1181 C CE1 . PHE   A 1 148 ? 154.486 138.887 158.229 1.00 74.17  ? 173 PHE   A CE1 1 
ATOM   1182 C CE2 . PHE   A 1 148 ? 153.288 138.998 156.176 1.00 69.21  ? 173 PHE   A CE2 1 
ATOM   1183 C CZ  . PHE   A 1 148 ? 154.312 138.476 156.928 1.00 69.07  ? 173 PHE   A CZ  1 
ATOM   1184 N N   . MET   A 1 149 ? 148.532 142.242 159.224 1.00 68.30  ? 174 MET   A N   1 
ATOM   1185 C CA  . MET   A 1 149 ? 147.694 143.357 159.630 1.00 70.26  ? 174 MET   A CA  1 
ATOM   1186 C C   . MET   A 1 149 ? 146.817 142.970 160.811 1.00 71.52  ? 174 MET   A C   1 
ATOM   1187 O O   . MET   A 1 149 ? 146.331 141.839 160.899 1.00 77.46  ? 174 MET   A O   1 
ATOM   1188 C CB  . MET   A 1 149 ? 146.828 143.809 158.457 1.00 73.39  ? 174 MET   A CB  1 
ATOM   1189 C CG  . MET   A 1 149 ? 147.640 144.175 157.232 1.00 73.17  ? 174 MET   A CG  1 
ATOM   1190 S SD  . MET   A 1 149 ? 146.669 144.776 155.851 1.00 80.32  ? 174 MET   A SD  1 
ATOM   1191 C CE  . MET   A 1 149 ? 148.000 145.109 154.711 1.00 73.59  ? 174 MET   A CE  1 
ATOM   1192 N N   . ASP   A 1 150 ? 146.616 143.921 161.723 1.00 69.51  ? 175 ASP   A N   1 
ATOM   1193 C CA  . ASP   A 1 150 ? 145.783 143.705 162.905 1.00 72.43  ? 175 ASP   A CA  1 
ATOM   1194 C C   . ASP   A 1 150 ? 144.332 143.977 162.525 1.00 70.73  ? 175 ASP   A C   1 
ATOM   1195 O O   . ASP   A 1 150 ? 143.740 144.999 162.875 1.00 74.36  ? 175 ASP   A O   1 
ATOM   1196 C CB  . ASP   A 1 150 ? 146.244 144.594 164.052 1.00 79.52  ? 175 ASP   A CB  1 
ATOM   1197 C CG  . ASP   A 1 150 ? 147.722 144.440 164.351 1.00 88.42  ? 175 ASP   A CG  1 
ATOM   1198 O OD1 . ASP   A 1 150 ? 148.545 144.932 163.551 1.00 85.62  ? 175 ASP   A OD1 1 
ATOM   1199 O OD2 . ASP   A 1 150 ? 148.061 143.826 165.384 1.00 91.13  ? 175 ASP   A OD2 1 
ATOM   1200 N N   . ALA   A 1 151 ? 143.750 143.027 161.799 1.00 68.28  ? 176 ALA   A N   1 
ATOM   1201 C CA  . ALA   A 1 151 ? 142.399 143.157 161.272 1.00 64.10  ? 176 ALA   A CA  1 
ATOM   1202 C C   . ALA   A 1 151 ? 141.336 142.538 162.169 1.00 66.51  ? 176 ALA   A C   1 
ATOM   1203 O O   . ALA   A 1 151 ? 140.161 142.540 161.790 1.00 69.38  ? 176 ALA   A O   1 
ATOM   1204 C CB  . ALA   A 1 151 ? 142.317 142.518 159.883 1.00 64.61  ? 176 ALA   A CB  1 
ATOM   1205 N N   . ASN   A 1 152 ? 141.707 142.011 163.336 1.00 67.84  ? 177 ASN   A N   1 
ATOM   1206 C CA  . ASN   A 1 152 ? 140.769 141.391 164.263 1.00 68.53  ? 177 ASN   A CA  1 
ATOM   1207 C C   . ASN   A 1 152 ? 140.398 142.301 165.426 1.00 73.10  ? 177 ASN   A C   1 
ATOM   1208 O O   . ASN   A 1 152 ? 139.824 141.826 166.409 1.00 76.31  ? 177 ASN   A O   1 
ATOM   1209 C CB  . ASN   A 1 152 ? 141.349 140.081 164.795 1.00 68.95  ? 177 ASN   A CB  1 
ATOM   1210 C CG  . ASN   A 1 152 ? 142.596 140.290 165.620 1.00 73.73  ? 177 ASN   A CG  1 
ATOM   1211 O OD1 . ASN   A 1 152 ? 143.280 141.301 165.481 1.00 74.87  ? 177 ASN   A OD1 1 
ATOM   1212 N ND2 . ASN   A 1 152 ? 142.903 139.331 166.482 1.00 77.25  ? 177 ASN   A ND2 1 
ATOM   1213 N N   . HIS   A 1 153 ? 140.710 143.593 165.341 1.00 71.35  ? 178 HIS   A N   1 
ATOM   1214 C CA  . HIS   A 1 153 ? 140.480 144.502 166.453 1.00 69.68  ? 178 HIS   A CA  1 
ATOM   1215 C C   . HIS   A 1 153 ? 139.030 144.949 166.585 1.00 71.79  ? 178 HIS   A C   1 
ATOM   1216 O O   . HIS   A 1 153 ? 138.671 145.496 167.633 1.00 78.23  ? 178 HIS   A O   1 
ATOM   1217 C CB  . HIS   A 1 153 ? 141.378 145.731 166.313 1.00 63.52  ? 178 HIS   A CB  1 
ATOM   1218 C CG  . HIS   A 1 153 ? 142.795 145.502 166.740 1.00 65.17  ? 178 HIS   A CG  1 
ATOM   1219 N ND1 . HIS   A 1 153 ? 143.652 146.535 167.044 1.00 68.98  ? 178 HIS   A ND1 1 
ATOM   1220 C CD2 . HIS   A 1 153 ? 143.502 144.362 166.923 1.00 70.81  ? 178 HIS   A CD2 1 
ATOM   1221 C CE1 . HIS   A 1 153 ? 144.827 146.043 167.391 1.00 69.28  ? 178 HIS   A CE1 1 
ATOM   1222 N NE2 . HIS   A 1 153 ? 144.762 144.726 167.328 1.00 70.33  ? 178 HIS   A NE2 1 
ATOM   1223 N N   . TYR   A 1 154 ? 138.195 144.745 165.567 1.00 65.22  ? 179 TYR   A N   1 
ATOM   1224 C CA  . TYR   A 1 154 ? 136.810 145.196 165.601 1.00 64.65  ? 179 TYR   A CA  1 
ATOM   1225 C C   . TYR   A 1 154 ? 135.924 144.189 164.889 1.00 70.14  ? 179 TYR   A C   1 
ATOM   1226 O O   . TYR   A 1 154 ? 136.245 143.750 163.781 1.00 73.60  ? 179 TYR   A O   1 
ATOM   1227 C CB  . TYR   A 1 154 ? 136.693 146.575 164.957 1.00 66.20  ? 179 TYR   A CB  1 
ATOM   1228 C CG  . TYR   A 1 154 ? 135.301 147.156 164.879 1.00 67.89  ? 179 TYR   A CG  1 
ATOM   1229 C CD1 . TYR   A 1 154 ? 134.760 147.852 165.946 1.00 72.46  ? 179 TYR   A CD1 1 
ATOM   1230 C CD2 . TYR   A 1 154 ? 134.547 147.048 163.725 1.00 66.75  ? 179 TYR   A CD2 1 
ATOM   1231 C CE1 . TYR   A 1 154 ? 133.501 148.399 165.872 1.00 73.45  ? 179 TYR   A CE1 1 
ATOM   1232 C CE2 . TYR   A 1 154 ? 133.290 147.593 163.643 1.00 64.47  ? 179 TYR   A CE2 1 
ATOM   1233 C CZ  . TYR   A 1 154 ? 132.771 148.266 164.718 1.00 70.23  ? 179 TYR   A CZ  1 
ATOM   1234 O OH  . TYR   A 1 154 ? 131.513 148.812 164.639 1.00 79.46  ? 179 TYR   A OH  1 
ATOM   1235 N N   . TRP   A 1 155 ? 134.811 143.834 165.528 1.00 67.59  ? 180 TRP   A N   1 
ATOM   1236 C CA  . TRP   A 1 155 ? 133.867 142.850 165.002 1.00 63.92  ? 180 TRP   A CA  1 
ATOM   1237 C C   . TRP   A 1 155 ? 134.570 141.518 164.743 1.00 63.48  ? 180 TRP   A C   1 
ATOM   1238 O O   . TRP   A 1 155 ? 134.643 141.026 163.617 1.00 71.16  ? 180 TRP   A O   1 
ATOM   1239 C CB  . TRP   A 1 155 ? 133.186 143.372 163.732 1.00 66.91  ? 180 TRP   A CB  1 
ATOM   1240 C CG  . TRP   A 1 155 ? 132.023 142.545 163.249 1.00 70.57  ? 180 TRP   A CG  1 
ATOM   1241 C CD1 . TRP   A 1 155 ? 131.278 141.658 163.974 1.00 74.26  ? 180 TRP   A CD1 1 
ATOM   1242 C CD2 . TRP   A 1 155 ? 131.475 142.536 161.927 1.00 73.32  ? 180 TRP   A CD2 1 
ATOM   1243 N NE1 . TRP   A 1 155 ? 130.303 141.102 163.186 1.00 77.36  ? 180 TRP   A NE1 1 
ATOM   1244 C CE2 . TRP   A 1 155 ? 130.402 141.625 161.924 1.00 70.41  ? 180 TRP   A CE2 1 
ATOM   1245 C CE3 . TRP   A 1 155 ? 131.788 143.211 160.744 1.00 76.15  ? 180 TRP   A CE3 1 
ATOM   1246 C CZ2 . TRP   A 1 155 ? 129.645 141.369 160.788 1.00 69.05  ? 180 TRP   A CZ2 1 
ATOM   1247 C CZ3 . TRP   A 1 155 ? 131.033 142.956 159.618 1.00 76.93  ? 180 TRP   A CZ3 1 
ATOM   1248 C CH2 . TRP   A 1 155 ? 129.974 142.044 159.647 1.00 73.20  ? 180 TRP   A CH2 1 
ATOM   1249 N N   . SER   A 1 156 ? 135.101 140.946 165.820 1.00 57.77  ? 181 SER   A N   1 
ATOM   1250 C CA  . SER   A 1 156 ? 135.804 139.677 165.749 1.00 65.04  ? 181 SER   A CA  1 
ATOM   1251 C C   . SER   A 1 156 ? 135.536 138.885 167.017 1.00 69.56  ? 181 SER   A C   1 
ATOM   1252 O O   . SER   A 1 156 ? 135.337 139.456 168.092 1.00 76.22  ? 181 SER   A O   1 
ATOM   1253 C CB  . SER   A 1 156 ? 137.310 139.881 165.568 1.00 74.12  ? 181 SER   A CB  1 
ATOM   1254 O OG  . SER   A 1 156 ? 137.869 140.542 166.688 1.00 79.61  ? 181 SER   A OG  1 
ATOM   1255 N N   . VAL   A 1 157 ? 135.532 137.558 166.879 1.00 69.05  ? 182 VAL   A N   1 
ATOM   1256 C CA  . VAL   A 1 157 ? 135.372 136.692 168.040 1.00 68.83  ? 182 VAL   A CA  1 
ATOM   1257 C C   . VAL   A 1 157 ? 136.579 136.800 168.957 1.00 74.37  ? 182 VAL   A C   1 
ATOM   1258 O O   . VAL   A 1 157 ? 136.444 136.708 170.182 1.00 83.10  ? 182 VAL   A O   1 
ATOM   1259 C CB  . VAL   A 1 157 ? 135.127 135.239 167.598 1.00 68.52  ? 182 VAL   A CB  1 
ATOM   1260 C CG1 . VAL   A 1 157 ? 135.103 134.312 168.804 1.00 71.15  ? 182 VAL   A CG1 1 
ATOM   1261 C CG2 . VAL   A 1 157 ? 133.825 135.135 166.821 1.00 70.32  ? 182 VAL   A CG2 1 
ATOM   1262 N N   . ASP   A 1 158 ? 137.775 136.984 168.390 1.00 72.08  ? 183 ASP   A N   1 
ATOM   1263 C CA  . ASP   A 1 158 ? 138.970 137.133 169.214 1.00 79.76  ? 183 ASP   A CA  1 
ATOM   1264 C C   . ASP   A 1 158 ? 138.871 138.351 170.123 1.00 83.03  ? 183 ASP   A C   1 
ATOM   1265 O O   . ASP   A 1 158 ? 139.454 138.360 171.213 1.00 87.32  ? 183 ASP   A O   1 
ATOM   1266 C CB  . ASP   A 1 158 ? 140.209 137.231 168.325 1.00 79.57  ? 183 ASP   A CB  1 
ATOM   1267 C CG  . ASP   A 1 158 ? 141.500 137.261 169.120 1.00 91.15  ? 183 ASP   A CG  1 
ATOM   1268 O OD1 . ASP   A 1 158 ? 141.484 136.882 170.310 1.00 94.99  ? 183 ASP   A OD1 1 
ATOM   1269 O OD2 . ASP   A 1 158 ? 142.537 137.665 168.552 1.00 95.25  ? 183 ASP   A OD2 1 
ATOM   1270 N N   . GLY   A 1 159 ? 138.138 139.380 169.700 1.00 82.48  ? 184 GLY   A N   1 
ATOM   1271 C CA  . GLY   A 1 159 ? 137.907 140.515 170.576 1.00 83.64  ? 184 GLY   A CA  1 
ATOM   1272 C C   . GLY   A 1 159 ? 137.137 140.133 171.824 1.00 84.65  ? 184 GLY   A C   1 
ATOM   1273 O O   . GLY   A 1 159 ? 137.457 140.586 172.925 1.00 88.51  ? 184 GLY   A O   1 
ATOM   1274 N N   . LEU   A 1 160 ? 136.107 139.299 171.671 1.00 81.14  ? 185 LEU   A N   1 
ATOM   1275 C CA  . LEU   A 1 160 ? 135.332 138.868 172.828 1.00 81.46  ? 185 LEU   A CA  1 
ATOM   1276 C C   . LEU   A 1 160 ? 136.167 138.024 173.782 1.00 84.25  ? 185 LEU   A C   1 
ATOM   1277 O O   . LEU   A 1 160 ? 135.960 138.082 174.999 1.00 85.31  ? 185 LEU   A O   1 
ATOM   1278 C CB  . LEU   A 1 160 ? 134.101 138.088 172.374 1.00 76.28  ? 185 LEU   A CB  1 
ATOM   1279 C CG  . LEU   A 1 160 ? 133.101 138.845 171.500 1.00 79.27  ? 185 LEU   A CG  1 
ATOM   1280 C CD1 . LEU   A 1 160 ? 132.043 137.895 170.973 1.00 80.65  ? 185 LEU   A CD1 1 
ATOM   1281 C CD2 . LEU   A 1 160 ? 132.455 139.988 172.267 1.00 83.56  ? 185 LEU   A CD2 1 
ATOM   1282 N N   . LEU   A 1 161 ? 137.107 137.243 173.259 1.00 84.62  ? 186 LEU   A N   1 
ATOM   1283 C CA  . LEU   A 1 161 ? 137.959 136.390 174.076 1.00 86.09  ? 186 LEU   A CA  1 
ATOM   1284 C C   . LEU   A 1 161 ? 139.180 137.113 174.630 1.00 87.13  ? 186 LEU   A C   1 
ATOM   1285 O O   . LEU   A 1 161 ? 139.941 136.508 175.392 1.00 90.25  ? 186 LEU   A O   1 
ATOM   1286 C CB  . LEU   A 1 161 ? 138.416 135.170 173.265 1.00 88.81  ? 186 LEU   A CB  1 
ATOM   1287 C CG  . LEU   A 1 161 ? 137.462 133.974 173.209 1.00 92.51  ? 186 LEU   A CG  1 
ATOM   1288 C CD1 . LEU   A 1 161 ? 136.142 134.331 172.542 1.00 91.11  ? 186 LEU   A CD1 1 
ATOM   1289 C CD2 . LEU   A 1 161 ? 138.127 132.813 172.486 1.00 87.74  ? 186 LEU   A CD2 1 
ATOM   1290 N N   . ASN   A 1 162 ? 139.391 138.380 174.278 1.00 86.04  ? 187 ASN   A N   1 
ATOM   1291 C CA  . ASN   A 1 162 ? 140.535 139.134 174.779 1.00 89.62  ? 187 ASN   A CA  1 
ATOM   1292 C C   . ASN   A 1 162 ? 140.171 140.609 174.790 1.00 88.96  ? 187 ASN   A C   1 
ATOM   1293 O O   . ASN   A 1 162 ? 139.936 141.199 173.731 1.00 88.69  ? 187 ASN   A O   1 
ATOM   1294 C CB  . ASN   A 1 162 ? 141.773 138.887 173.917 1.00 90.52  ? 187 ASN   A CB  1 
ATOM   1295 C CG  . ASN   A 1 162 ? 143.011 139.557 174.471 1.00 95.80  ? 187 ASN   A CG  1 
ATOM   1296 O OD1 . ASN   A 1 162 ? 143.041 139.973 175.629 1.00 99.44  ? 187 ASN   A OD1 1 
ATOM   1297 N ND2 . ASN   A 1 162 ? 144.045 139.664 173.645 1.00 96.90  ? 187 ASN   A ND2 1 
ATOM   1298 N N   . ALA   A 1 163 ? 140.136 141.202 175.985 1.00 87.06  ? 188 ALA   A N   1 
ATOM   1299 C CA  . ALA   A 1 163 ? 139.706 142.590 176.116 1.00 86.25  ? 188 ALA   A CA  1 
ATOM   1300 C C   . ALA   A 1 163 ? 140.671 143.542 175.421 1.00 85.15  ? 188 ALA   A C   1 
ATOM   1301 O O   . ALA   A 1 163 ? 140.251 144.571 174.879 1.00 84.46  ? 188 ALA   A O   1 
ATOM   1302 C CB  . ALA   A 1 163 ? 139.567 142.955 177.593 1.00 86.04  ? 188 ALA   A CB  1 
ATOM   1303 N N   . HIS   A 1 164 ? 141.966 143.224 175.433 1.00 86.84  ? 189 HIS   A N   1 
ATOM   1304 C CA  . HIS   A 1 164 ? 142.966 144.125 174.871 1.00 85.19  ? 189 HIS   A CA  1 
ATOM   1305 C C   . HIS   A 1 164 ? 142.792 144.345 173.373 1.00 87.12  ? 189 HIS   A C   1 
ATOM   1306 O O   . HIS   A 1 164 ? 143.250 145.370 172.858 1.00 85.75  ? 189 HIS   A O   1 
ATOM   1307 C CB  . HIS   A 1 164 ? 144.369 143.581 175.146 1.00 90.89  ? 189 HIS   A CB  1 
ATOM   1308 C CG  . HIS   A 1 164 ? 144.683 143.424 176.601 1.00 101.62 ? 189 HIS   A CG  1 
ATOM   1309 N ND1 . HIS   A 1 164 ? 145.257 144.427 177.351 1.00 108.19 ? 189 HIS   A ND1 1 
ATOM   1310 C CD2 . HIS   A 1 164 ? 144.502 142.381 177.445 1.00 103.08 ? 189 HIS   A CD2 1 
ATOM   1311 C CE1 . HIS   A 1 164 ? 145.417 144.009 178.594 1.00 108.92 ? 189 HIS   A CE1 1 
ATOM   1312 N NE2 . HIS   A 1 164 ? 144.967 142.770 178.678 1.00 108.55 ? 189 HIS   A NE2 1 
ATOM   1313 N N   . ARG   A 1 165 ? 142.146 143.415 172.666 1.00 88.16  ? 190 ARG   A N   1 
ATOM   1314 C CA  . ARG   A 1 165 ? 141.984 143.476 171.218 1.00 83.83  ? 190 ARG   A CA  1 
ATOM   1315 C C   . ARG   A 1 165 ? 140.526 143.669 170.810 1.00 82.69  ? 190 ARG   A C   1 
ATOM   1316 O O   . ARG   A 1 165 ? 140.098 143.162 169.770 1.00 83.52  ? 190 ARG   A O   1 
ATOM   1317 C CB  . ARG   A 1 165 ? 142.549 142.213 170.570 1.00 87.57  ? 190 ARG   A CB  1 
ATOM   1318 C CG  . ARG   A 1 165 ? 144.022 141.981 170.862 1.00 94.54  ? 190 ARG   A CG  1 
ATOM   1319 C CD  . ARG   A 1 165 ? 144.559 140.775 170.112 1.00 97.50  ? 190 ARG   A CD  1 
ATOM   1320 N NE  . ARG   A 1 165 ? 145.991 140.592 170.331 1.00 104.28 ? 190 ARG   A NE  1 
ATOM   1321 C CZ  . ARG   A 1 165 ? 146.950 141.263 169.704 1.00 107.65 ? 190 ARG   A CZ  1 
ATOM   1322 N NH1 . ARG   A 1 165 ? 146.678 142.198 168.807 1.00 101.49 ? 190 ARG   A NH1 1 
ATOM   1323 N NH2 . ARG   A 1 165 ? 148.221 140.990 169.988 1.00 107.98 ? 190 ARG   A NH2 1 
ATOM   1324 N N   . ARG   A 1 166 ? 139.756 144.403 171.614 1.00 81.17  ? 191 ARG   A N   1 
ATOM   1325 C CA  . ARG   A 1 166 ? 138.338 144.647 171.366 1.00 76.36  ? 191 ARG   A CA  1 
ATOM   1326 C C   . ARG   A 1 166 ? 138.150 146.134 171.090 1.00 73.55  ? 191 ARG   A C   1 
ATOM   1327 O O   . ARG   A 1 166 ? 138.222 146.957 172.008 1.00 75.78  ? 191 ARG   A O   1 
ATOM   1328 C CB  . ARG   A 1 166 ? 137.497 144.189 172.555 1.00 82.13  ? 191 ARG   A CB  1 
ATOM   1329 C CG  . ARG   A 1 166 ? 136.160 143.573 172.168 1.00 87.62  ? 191 ARG   A CG  1 
ATOM   1330 C CD  . ARG   A 1 166 ? 135.463 142.921 173.357 1.00 93.03  ? 191 ARG   A CD  1 
ATOM   1331 N NE  . ARG   A 1 166 ? 134.735 143.883 174.178 1.00 99.54  ? 191 ARG   A NE  1 
ATOM   1332 C CZ  . ARG   A 1 166 ? 133.486 144.280 173.965 1.00 101.24 ? 191 ARG   A CZ  1 
ATOM   1333 N NH1 . ARG   A 1 166 ? 132.778 143.843 172.934 1.00 97.79  ? 191 ARG   A NH1 1 
ATOM   1334 N NH2 . ARG   A 1 166 ? 132.929 145.142 174.811 1.00 100.45 ? 191 ARG   A NH2 1 
ATOM   1335 N N   . ASN   A 1 167 ? 137.909 146.472 169.823 1.00 71.16  ? 192 ASN   A N   1 
ATOM   1336 C CA  . ASN   A 1 167 ? 137.668 147.848 169.396 1.00 65.74  ? 192 ASN   A CA  1 
ATOM   1337 C C   . ASN   A 1 167 ? 138.863 148.741 169.735 1.00 65.81  ? 192 ASN   A C   1 
ATOM   1338 O O   . ASN   A 1 167 ? 138.758 149.715 170.484 1.00 69.60  ? 192 ASN   A O   1 
ATOM   1339 C CB  . ASN   A 1 167 ? 136.376 148.386 170.016 1.00 65.85  ? 192 ASN   A CB  1 
ATOM   1340 C CG  . ASN   A 1 167 ? 135.826 149.577 169.267 1.00 71.30  ? 192 ASN   A CG  1 
ATOM   1341 O OD1 . ASN   A 1 167 ? 136.571 150.331 168.644 1.00 74.64  ? 192 ASN   A OD1 1 
ATOM   1342 N ND2 . ASN   A 1 167 ? 134.512 149.752 169.318 1.00 74.55  ? 192 ASN   A ND2 1 
ATOM   1343 N N   . ALA   A 1 168 ? 140.009 148.388 169.160 1.00 62.56  ? 193 ALA   A N   1 
ATOM   1344 C CA  . ALA   A 1 168 ? 141.276 149.062 169.403 1.00 65.03  ? 193 ALA   A CA  1 
ATOM   1345 C C   . ALA   A 1 168 ? 141.806 149.662 168.108 1.00 65.87  ? 193 ALA   A C   1 
ATOM   1346 O O   . ALA   A 1 168 ? 141.331 149.359 167.011 1.00 70.86  ? 193 ALA   A O   1 
ATOM   1347 C CB  . ALA   A 1 168 ? 142.305 148.095 169.999 1.00 69.49  ? 193 ALA   A CB  1 
ATOM   1348 N N   . HIS   A 1 169 ? 142.807 150.526 168.250 1.00 63.82  ? 194 HIS   A N   1 
ATOM   1349 C CA  . HIS   A 1 169 ? 143.398 151.200 167.106 1.00 63.71  ? 194 HIS   A CA  1 
ATOM   1350 C C   . HIS   A 1 169 ? 144.276 150.244 166.307 1.00 63.82  ? 194 HIS   A C   1 
ATOM   1351 O O   . HIS   A 1 169 ? 144.692 149.187 166.789 1.00 66.48  ? 194 HIS   A O   1 
ATOM   1352 C CB  . HIS   A 1 169 ? 144.242 152.394 167.554 1.00 64.95  ? 194 HIS   A CB  1 
ATOM   1353 C CG  . HIS   A 1 169 ? 143.448 153.595 167.964 1.00 63.62  ? 194 HIS   A CG  1 
ATOM   1354 N ND1 . HIS   A 1 169 ? 143.855 154.440 168.973 1.00 64.32  ? 194 HIS   A ND1 1 
ATOM   1355 C CD2 . HIS   A 1 169 ? 142.294 154.114 167.483 1.00 62.39  ? 194 HIS   A CD2 1 
ATOM   1356 C CE1 . HIS   A 1 169 ? 142.977 155.416 169.108 1.00 61.28  ? 194 HIS   A CE1 1 
ATOM   1357 N NE2 . HIS   A 1 169 ? 142.021 155.244 168.214 1.00 63.03  ? 194 HIS   A NE2 1 
ATOM   1358 N N   . VAL   A 1 170 ? 144.539 150.629 165.059 1.00 62.45  ? 195 VAL   A N   1 
ATOM   1359 C CA  . VAL   A 1 170 ? 145.455 149.894 164.183 1.00 62.81  ? 195 VAL   A CA  1 
ATOM   1360 C C   . VAL   A 1 170 ? 146.358 150.882 163.467 1.00 66.25  ? 195 VAL   A C   1 
ATOM   1361 O O   . VAL   A 1 170 ? 145.980 152.037 163.230 1.00 71.88  ? 195 VAL   A O   1 
ATOM   1362 C CB  . VAL   A 1 170 ? 144.698 149.039 163.144 1.00 58.90  ? 195 VAL   A CB  1 
ATOM   1363 C CG1 . VAL   A 1 170 ? 143.794 148.036 163.840 1.00 64.19  ? 195 VAL   A CG1 1 
ATOM   1364 C CG2 . VAL   A 1 170 ? 143.903 149.915 162.182 1.00 58.89  ? 195 VAL   A CG2 1 
ATOM   1365 N N   . PRO   A 1 171 ? 147.573 150.456 163.107 1.00 60.31  ? 196 PRO   A N   1 
ATOM   1366 C CA  . PRO   A 1 171 ? 148.462 151.360 162.373 1.00 57.73  ? 196 PRO   A CA  1 
ATOM   1367 C C   . PRO   A 1 171 ? 147.941 151.651 160.976 1.00 64.57  ? 196 PRO   A C   1 
ATOM   1368 O O   . PRO   A 1 171 ? 147.183 150.873 160.393 1.00 71.56  ? 196 PRO   A O   1 
ATOM   1369 C CB  . PRO   A 1 171 ? 149.787 150.597 162.327 1.00 63.01  ? 196 PRO   A CB  1 
ATOM   1370 C CG  . PRO   A 1 171 ? 149.415 149.192 162.447 1.00 66.94  ? 196 PRO   A CG  1 
ATOM   1371 C CD  . PRO   A 1 171 ? 148.223 149.154 163.342 1.00 66.17  ? 196 PRO   A CD  1 
ATOM   1372 N N   . LEU   A 1 172 ? 148.361 152.798 160.438 1.00 61.58  ? 197 LEU   A N   1 
ATOM   1373 C CA  . LEU   A 1 172 ? 147.846 153.247 159.150 1.00 59.99  ? 197 LEU   A CA  1 
ATOM   1374 C C   . LEU   A 1 172 ? 148.386 152.440 157.978 1.00 65.47  ? 197 LEU   A C   1 
ATOM   1375 O O   . LEU   A 1 172 ? 147.733 152.400 156.930 1.00 70.22  ? 197 LEU   A O   1 
ATOM   1376 C CB  . LEU   A 1 172 ? 148.172 154.726 158.938 1.00 58.40  ? 197 LEU   A CB  1 
ATOM   1377 C CG  . LEU   A 1 172 ? 147.782 155.360 157.597 1.00 62.49  ? 197 LEU   A CG  1 
ATOM   1378 C CD1 . LEU   A 1 172 ? 146.296 155.212 157.338 1.00 64.88  ? 197 LEU   A CD1 1 
ATOM   1379 C CD2 . LEU   A 1 172 ? 148.169 156.817 157.569 1.00 64.14  ? 197 LEU   A CD2 1 
ATOM   1380 N N   . TRP   A 1 173 ? 149.550 151.800 158.111 1.00 63.87  ? 198 TRP   A N   1 
ATOM   1381 C CA  . TRP   A 1 173 ? 150.109 151.105 156.958 1.00 61.38  ? 198 TRP   A CA  1 
ATOM   1382 C C   . TRP   A 1 173 ? 149.271 149.901 156.548 1.00 65.44  ? 198 TRP   A C   1 
ATOM   1383 O O   . TRP   A 1 173 ? 149.393 149.443 155.404 1.00 70.97  ? 198 TRP   A O   1 
ATOM   1384 C CB  . TRP   A 1 173 ? 151.560 150.690 157.222 1.00 63.40  ? 198 TRP   A CB  1 
ATOM   1385 C CG  . TRP   A 1 173 ? 151.782 149.675 158.300 1.00 63.84  ? 198 TRP   A CG  1 
ATOM   1386 C CD1 . TRP   A 1 173 ? 152.139 149.919 159.589 1.00 65.24  ? 198 TRP   A CD1 1 
ATOM   1387 C CD2 . TRP   A 1 173 ? 151.699 148.251 158.171 1.00 68.12  ? 198 TRP   A CD2 1 
ATOM   1388 N NE1 . TRP   A 1 173 ? 152.272 148.740 160.277 1.00 65.44  ? 198 TRP   A NE1 1 
ATOM   1389 C CE2 . TRP   A 1 173 ? 152.006 147.700 159.428 1.00 64.77  ? 198 TRP   A CE2 1 
ATOM   1390 C CE3 . TRP   A 1 173 ? 151.390 147.389 157.115 1.00 70.90  ? 198 TRP   A CE3 1 
ATOM   1391 C CZ2 . TRP   A 1 173 ? 152.007 146.330 159.661 1.00 67.62  ? 198 TRP   A CZ2 1 
ATOM   1392 C CZ3 . TRP   A 1 173 ? 151.393 146.029 157.349 1.00 68.82  ? 198 TRP   A CZ3 1 
ATOM   1393 C CH2 . TRP   A 1 173 ? 151.700 145.514 158.611 1.00 69.54  ? 198 TRP   A CH2 1 
ATOM   1394 N N   . ASN   A 1 174 ? 148.412 149.397 157.439 1.00 63.39  ? 199 ASN   A N   1 
ATOM   1395 C CA  . ASN   A 1 174 ? 147.485 148.338 157.061 1.00 64.73  ? 199 ASN   A CA  1 
ATOM   1396 C C   . ASN   A 1 174 ? 146.586 148.784 155.916 1.00 66.20  ? 199 ASN   A C   1 
ATOM   1397 O O   . ASN   A 1 174 ? 146.402 148.055 154.934 1.00 71.37  ? 199 ASN   A O   1 
ATOM   1398 C CB  . ASN   A 1 174 ? 146.645 147.922 158.268 1.00 63.70  ? 199 ASN   A CB  1 
ATOM   1399 C CG  . ASN   A 1 174 ? 147.478 147.345 159.387 1.00 67.93  ? 199 ASN   A CG  1 
ATOM   1400 O OD1 . ASN   A 1 174 ? 148.554 146.796 159.157 1.00 73.70  ? 199 ASN   A OD1 1 
ATOM   1401 N ND2 . ASN   A 1 174 ? 146.982 147.462 160.609 1.00 67.48  ? 199 ASN   A ND2 1 
ATOM   1402 N N   . TYR   A 1 175 ? 146.017 149.985 156.021 1.00 59.09  ? 200 TYR   A N   1 
ATOM   1403 C CA  . TYR   A 1 175 ? 145.194 150.505 154.936 1.00 58.48  ? 200 TYR   A CA  1 
ATOM   1404 C C   . TYR   A 1 175 ? 146.044 150.877 153.729 1.00 62.85  ? 200 TYR   A C   1 
ATOM   1405 O O   . TYR   A 1 175 ? 145.615 150.698 152.582 1.00 69.56  ? 200 TYR   A O   1 
ATOM   1406 C CB  . TYR   A 1 175 ? 144.398 151.717 155.413 1.00 55.13  ? 200 TYR   A CB  1 
ATOM   1407 C CG  . TYR   A 1 175 ? 143.317 151.392 156.411 1.00 54.79  ? 200 TYR   A CG  1 
ATOM   1408 C CD1 . TYR   A 1 175 ? 142.130 150.810 156.009 1.00 58.49  ? 200 TYR   A CD1 1 
ATOM   1409 C CD2 . TYR   A 1 175 ? 143.475 151.683 157.753 1.00 54.99  ? 200 TYR   A CD2 1 
ATOM   1410 C CE1 . TYR   A 1 175 ? 141.141 150.515 156.913 1.00 58.77  ? 200 TYR   A CE1 1 
ATOM   1411 C CE2 . TYR   A 1 175 ? 142.491 151.393 158.662 1.00 56.97  ? 200 TYR   A CE2 1 
ATOM   1412 C CZ  . TYR   A 1 175 ? 141.327 150.809 158.238 1.00 59.46  ? 200 TYR   A CZ  1 
ATOM   1413 O OH  . TYR   A 1 175 ? 140.337 150.515 159.142 1.00 62.93  ? 200 TYR   A OH  1 
ATOM   1414 N N   . ALA   A 1 176 ? 147.243 151.411 153.971 1.00 61.08  ? 201 ALA   A N   1 
ATOM   1415 C CA  . ALA   A 1 176 ? 148.079 151.888 152.877 1.00 60.92  ? 201 ALA   A CA  1 
ATOM   1416 C C   . ALA   A 1 176 ? 148.489 150.751 151.953 1.00 64.84  ? 201 ALA   A C   1 
ATOM   1417 O O   . ALA   A 1 176 ? 148.486 150.912 150.728 1.00 69.36  ? 201 ALA   A O   1 
ATOM   1418 C CB  . ALA   A 1 176 ? 149.314 152.595 153.431 1.00 63.08  ? 201 ALA   A CB  1 
ATOM   1419 N N   . VAL   A 1 177 ? 148.839 149.594 152.516 1.00 64.94  ? 202 VAL   A N   1 
ATOM   1420 C CA  . VAL   A 1 177 ? 149.283 148.475 151.687 1.00 63.57  ? 202 VAL   A CA  1 
ATOM   1421 C C   . VAL   A 1 177 ? 148.148 147.993 150.789 1.00 64.88  ? 202 VAL   A C   1 
ATOM   1422 O O   . VAL   A 1 177 ? 148.343 147.749 149.593 1.00 70.54  ? 202 VAL   A O   1 
ATOM   1423 C CB  . VAL   A 1 177 ? 149.833 147.342 152.571 1.00 64.60  ? 202 VAL   A CB  1 
ATOM   1424 C CG1 . VAL   A 1 177 ? 150.027 146.066 151.767 1.00 67.80  ? 202 VAL   A CG1 1 
ATOM   1425 C CG2 . VAL   A 1 177 ? 151.146 147.758 153.207 1.00 67.18  ? 202 VAL   A CG2 1 
ATOM   1426 N N   . LEU   A 1 178 ? 146.946 147.849 151.350 1.00 60.05  ? 203 LEU   A N   1 
ATOM   1427 C CA  . LEU   A 1 178 ? 145.812 147.388 150.553 1.00 61.81  ? 203 LEU   A CA  1 
ATOM   1428 C C   . LEU   A 1 178 ? 145.439 148.397 149.474 1.00 64.38  ? 203 LEU   A C   1 
ATOM   1429 O O   . LEU   A 1 178 ? 145.163 148.019 148.323 1.00 68.83  ? 203 LEU   A O   1 
ATOM   1430 C CB  . LEU   A 1 178 ? 144.616 147.110 151.463 1.00 62.80  ? 203 LEU   A CB  1 
ATOM   1431 C CG  . LEU   A 1 178 ? 144.807 145.958 152.453 1.00 64.36  ? 203 LEU   A CG  1 
ATOM   1432 C CD1 . LEU   A 1 178 ? 143.820 146.008 153.607 1.00 65.95  ? 203 LEU   A CD1 1 
ATOM   1433 C CD2 . LEU   A 1 178 ? 144.690 144.627 151.739 1.00 65.95  ? 203 LEU   A CD2 1 
ATOM   1434 N N   . ARG   A 1 179 ? 145.419 149.685 149.827 1.00 61.03  ? 204 ARG   A N   1 
ATOM   1435 C CA  . ARG   A 1 179 ? 145.116 150.713 148.840 1.00 60.78  ? 204 ARG   A CA  1 
ATOM   1436 C C   . ARG   A 1 179 ? 146.144 150.707 147.718 1.00 63.78  ? 204 ARG   A C   1 
ATOM   1437 O O   . ARG   A 1 179 ? 145.789 150.803 146.536 1.00 68.45  ? 204 ARG   A O   1 
ATOM   1438 C CB  . ARG   A 1 179 ? 145.067 152.082 149.514 1.00 60.66  ? 204 ARG   A CB  1 
ATOM   1439 C CG  . ARG   A 1 179 ? 143.890 152.277 150.449 1.00 58.15  ? 204 ARG   A CG  1 
ATOM   1440 C CD  . ARG   A 1 179 ? 144.053 153.538 151.283 1.00 59.37  ? 204 ARG   A CD  1 
ATOM   1441 N NE  . ARG   A 1 179 ? 142.856 153.849 152.055 1.00 56.28  ? 204 ARG   A NE  1 
ATOM   1442 C CZ  . ARG   A 1 179 ? 142.748 154.850 152.919 1.00 59.48  ? 204 ARG   A CZ  1 
ATOM   1443 N NH1 . ARG   A 1 179 ? 143.757 155.671 153.163 1.00 65.47  ? 204 ARG   A NH1 1 
ATOM   1444 N NH2 . ARG   A 1 179 ? 141.597 155.034 153.556 1.00 59.79  ? 204 ARG   A NH2 1 
ATOM   1445 N N   . GLY   A 1 180 ? 147.424 150.579 148.068 1.00 63.63  ? 205 GLY   A N   1 
ATOM   1446 C CA  . GLY   A 1 180 ? 148.456 150.506 147.052 1.00 62.07  ? 205 GLY   A CA  1 
ATOM   1447 C C   . GLY   A 1 180 ? 148.321 149.281 146.173 1.00 62.97  ? 205 GLY   A C   1 
ATOM   1448 O O   . GLY   A 1 180 ? 148.577 149.343 144.972 1.00 69.01  ? 205 GLY   A O   1 
ATOM   1449 N N   . GLN   A 1 181 ? 147.918 148.150 146.756 1.00 59.46  ? 206 GLN   A N   1 
ATOM   1450 C CA  . GLN   A 1 181 ? 147.735 146.941 145.960 1.00 58.85  ? 206 GLN   A CA  1 
ATOM   1451 C C   . GLN   A 1 181 ? 146.632 147.129 144.926 1.00 60.71  ? 206 GLN   A C   1 
ATOM   1452 O O   . GLN   A 1 181 ? 146.808 146.803 143.744 1.00 65.31  ? 206 GLN   A O   1 
ATOM   1453 C CB  . GLN   A 1 181 ? 147.420 145.755 146.872 1.00 58.70  ? 206 GLN   A CB  1 
ATOM   1454 C CG  . GLN   A 1 181 ? 147.350 144.406 146.169 1.00 60.52  ? 206 GLN   A CG  1 
ATOM   1455 C CD  . GLN   A 1 181 ? 148.680 143.981 145.592 1.00 64.91  ? 206 GLN   A CD  1 
ATOM   1456 O OE1 . GLN   A 1 181 ? 149.735 144.406 146.058 1.00 66.68  ? 206 GLN   A OE1 1 
ATOM   1457 N NE2 . GLN   A 1 181 ? 148.638 143.140 144.568 1.00 68.24  ? 206 GLN   A NE2 1 
ATOM   1458 N N   . ILE   A 1 182 ? 145.484 147.661 145.352 1.00 57.34  ? 207 ILE   A N   1 
ATOM   1459 C CA  . ILE   A 1 182 ? 144.383 147.850 144.409 1.00 57.96  ? 207 ILE   A CA  1 
ATOM   1460 C C   . ILE   A 1 182 ? 144.759 148.883 143.350 1.00 61.18  ? 207 ILE   A C   1 
ATOM   1461 O O   . ILE   A 1 182 ? 144.441 148.724 142.160 1.00 64.72  ? 207 ILE   A O   1 
ATOM   1462 C CB  . ILE   A 1 182 ? 143.092 148.242 145.155 1.00 57.19  ? 207 ILE   A CB  1 
ATOM   1463 C CG1 . ILE   A 1 182 ? 142.690 147.175 146.187 1.00 54.94  ? 207 ILE   A CG1 1 
ATOM   1464 C CG2 . ILE   A 1 182 ? 141.963 148.487 144.167 1.00 63.06  ? 207 ILE   A CG2 1 
ATOM   1465 C CD1 . ILE   A 1 182 ? 142.404 145.791 145.634 1.00 58.78  ? 207 ILE   A CD1 1 
ATOM   1466 N N   . PHE   A 1 183 ? 145.452 149.949 143.760 1.00 59.51  ? 208 PHE   A N   1 
ATOM   1467 C CA  . PHE   A 1 183 ? 145.893 150.958 142.805 1.00 57.84  ? 208 PHE   A CA  1 
ATOM   1468 C C   . PHE   A 1 183 ? 146.867 150.373 141.793 1.00 60.63  ? 208 PHE   A C   1 
ATOM   1469 O O   . PHE   A 1 183 ? 146.795 150.689 140.601 1.00 64.91  ? 208 PHE   A O   1 
ATOM   1470 C CB  . PHE   A 1 183 ? 146.535 152.127 143.546 1.00 61.61  ? 208 PHE   A CB  1 
ATOM   1471 C CG  . PHE   A 1 183 ? 147.075 153.191 142.643 1.00 62.12  ? 208 PHE   A CG  1 
ATOM   1472 C CD1 . PHE   A 1 183 ? 146.235 154.130 142.091 1.00 62.15  ? 208 PHE   A CD1 1 
ATOM   1473 C CD2 . PHE   A 1 183 ? 148.423 153.257 142.354 1.00 65.48  ? 208 PHE   A CD2 1 
ATOM   1474 C CE1 . PHE   A 1 183 ? 146.722 155.111 141.261 1.00 65.50  ? 208 PHE   A CE1 1 
ATOM   1475 C CE2 . PHE   A 1 183 ? 148.918 154.234 141.524 1.00 65.89  ? 208 PHE   A CE2 1 
ATOM   1476 C CZ  . PHE   A 1 183 ? 148.066 155.164 140.977 1.00 67.65  ? 208 PHE   A CZ  1 
ATOM   1477 N N   . ILE   A 1 184 ? 147.793 149.528 142.250 1.00 61.86  ? 209 ILE   A N   1 
ATOM   1478 C CA  . ILE   A 1 184 ? 148.744 148.899 141.340 1.00 58.67  ? 209 ILE   A CA  1 
ATOM   1479 C C   . ILE   A 1 184 ? 148.012 148.002 140.358 1.00 59.27  ? 209 ILE   A C   1 
ATOM   1480 O O   . ILE   A 1 184 ? 148.336 147.979 139.167 1.00 66.24  ? 209 ILE   A O   1 
ATOM   1481 C CB  . ILE   A 1 184 ? 149.817 148.126 142.130 1.00 58.43  ? 209 ILE   A CB  1 
ATOM   1482 C CG1 . ILE   A 1 184 ? 150.763 149.105 142.828 1.00 60.39  ? 209 ILE   A CG1 1 
ATOM   1483 C CG2 . ILE   A 1 184 ? 150.613 147.207 141.209 1.00 61.81  ? 209 ILE   A CG2 1 
ATOM   1484 C CD1 . ILE   A 1 184 ? 151.544 148.501 143.976 1.00 63.72  ? 209 ILE   A CD1 1 
ATOM   1485 N N   . VAL   A 1 185 ? 147.011 147.261 140.837 1.00 58.97  ? 210 VAL   A N   1 
ATOM   1486 C CA  . VAL   A 1 185 ? 146.240 146.393 139.948 1.00 59.41  ? 210 VAL   A CA  1 
ATOM   1487 C C   . VAL   A 1 185 ? 145.598 147.216 138.839 1.00 62.23  ? 210 VAL   A C   1 
ATOM   1488 O O   . VAL   A 1 185 ? 145.800 146.946 137.645 1.00 64.04  ? 210 VAL   A O   1 
ATOM   1489 C CB  . VAL   A 1 185 ? 145.188 145.605 140.751 1.00 56.25  ? 210 VAL   A CB  1 
ATOM   1490 C CG1 . VAL   A 1 185 ? 144.188 144.934 139.828 1.00 61.34  ? 210 VAL   A CG1 1 
ATOM   1491 C CG2 . VAL   A 1 185 ? 145.856 144.562 141.627 1.00 62.06  ? 210 VAL   A CG2 1 
ATOM   1492 N N   . TYR   A 1 186 ? 144.873 148.274 139.214 1.00 62.68  ? 211 TYR   A N   1 
ATOM   1493 C CA  . TYR   A 1 186 ? 144.182 149.084 138.212 1.00 58.57  ? 211 TYR   A CA  1 
ATOM   1494 C C   . TYR   A 1 186 ? 145.166 149.751 137.256 1.00 60.82  ? 211 TYR   A C   1 
ATOM   1495 O O   . TYR   A 1 186 ? 144.990 149.705 136.033 1.00 66.50  ? 211 TYR   A O   1 
ATOM   1496 C CB  . TYR   A 1 186 ? 143.310 150.140 138.890 1.00 61.10  ? 211 TYR   A CB  1 
ATOM   1497 C CG  . TYR   A 1 186 ? 141.979 149.635 139.396 1.00 62.67  ? 211 TYR   A CG  1 
ATOM   1498 C CD1 . TYR   A 1 186 ? 140.998 149.204 138.521 1.00 62.22  ? 211 TYR   A CD1 1 
ATOM   1499 C CD2 . TYR   A 1 186 ? 141.694 149.619 140.750 1.00 63.98  ? 211 TYR   A CD2 1 
ATOM   1500 C CE1 . TYR   A 1 186 ? 139.784 148.751 138.980 1.00 63.38  ? 211 TYR   A CE1 1 
ATOM   1501 C CE2 . TYR   A 1 186 ? 140.480 149.169 141.216 1.00 59.19  ? 211 TYR   A CE2 1 
ATOM   1502 C CZ  . TYR   A 1 186 ? 139.530 148.738 140.328 1.00 59.82  ? 211 TYR   A CZ  1 
ATOM   1503 O OH  . TYR   A 1 186 ? 138.320 148.288 140.791 1.00 67.42  ? 211 TYR   A OH  1 
ATOM   1504 N N   . PHE   A 1 187 ? 146.220 150.367 137.794 1.00 57.46  ? 212 PHE   A N   1 
ATOM   1505 C CA  . PHE   A 1 187 ? 147.123 151.147 136.957 1.00 57.82  ? 212 PHE   A CA  1 
ATOM   1506 C C   . PHE   A 1 187 ? 147.938 150.259 136.024 1.00 61.00  ? 212 PHE   A C   1 
ATOM   1507 O O   . PHE   A 1 187 ? 148.140 150.607 134.854 1.00 65.85  ? 212 PHE   A O   1 
ATOM   1508 C CB  . PHE   A 1 187 ? 148.046 151.987 137.833 1.00 60.72  ? 212 PHE   A CB  1 
ATOM   1509 C CG  . PHE   A 1 187 ? 148.766 153.066 137.088 1.00 64.40  ? 212 PHE   A CG  1 
ATOM   1510 C CD1 . PHE   A 1 187 ? 148.089 154.182 136.640 1.00 67.22  ? 212 PHE   A CD1 1 
ATOM   1511 C CD2 . PHE   A 1 187 ? 150.121 152.971 136.842 1.00 66.86  ? 212 PHE   A CD2 1 
ATOM   1512 C CE1 . PHE   A 1 187 ? 148.744 155.177 135.957 1.00 68.66  ? 212 PHE   A CE1 1 
ATOM   1513 C CE2 . PHE   A 1 187 ? 150.782 153.964 136.161 1.00 71.58  ? 212 PHE   A CE2 1 
ATOM   1514 C CZ  . PHE   A 1 187 ? 150.093 155.069 135.717 1.00 72.42  ? 212 PHE   A CZ  1 
ATOM   1515 N N   . ILE   A 1 188 ? 148.434 149.123 136.517 1.00 59.04  ? 213 ILE   A N   1 
ATOM   1516 C CA  . ILE   A 1 188 ? 149.217 148.243 135.661 1.00 53.69  ? 213 ILE   A CA  1 
ATOM   1517 C C   . ILE   A 1 188 ? 148.323 147.595 134.613 1.00 53.92  ? 213 ILE   A C   1 
ATOM   1518 O O   . ILE   A 1 188 ? 148.751 147.367 133.476 1.00 60.27  ? 213 ILE   A O   1 
ATOM   1519 C CB  . ILE   A 1 188 ? 149.972 147.192 136.496 1.00 59.10  ? 213 ILE   A CB  1 
ATOM   1520 C CG1 . ILE   A 1 188 ? 150.947 147.851 137.485 1.00 59.73  ? 213 ILE   A CG1 1 
ATOM   1521 C CG2 . ILE   A 1 188 ? 150.736 146.248 135.587 1.00 61.71  ? 213 ILE   A CG2 1 
ATOM   1522 C CD1 . ILE   A 1 188 ? 152.196 148.449 136.865 1.00 60.85  ? 213 ILE   A CD1 1 
ATOM   1523 N N   . ALA   A 1 189 ? 147.074 147.278 134.968 1.00 55.37  ? 214 ALA   A N   1 
ATOM   1524 C CA  . ALA   A 1 189 ? 146.145 146.792 133.957 1.00 56.17  ? 214 ALA   A CA  1 
ATOM   1525 C C   . ALA   A 1 189 ? 145.919 147.845 132.882 1.00 57.65  ? 214 ALA   A C   1 
ATOM   1526 O O   . ALA   A 1 189 ? 145.854 147.525 131.691 1.00 63.91  ? 214 ALA   A O   1 
ATOM   1527 C CB  . ALA   A 1 189 ? 144.823 146.392 134.607 1.00 60.13  ? 214 ALA   A CB  1 
ATOM   1528 N N   . GLY   A 1 190 ? 145.797 149.110 133.285 1.00 57.32  ? 215 GLY   A N   1 
ATOM   1529 C CA  . GLY   A 1 190 ? 145.608 150.167 132.306 1.00 61.03  ? 215 GLY   A CA  1 
ATOM   1530 C C   . GLY   A 1 190 ? 146.802 150.343 131.387 1.00 60.26  ? 215 GLY   A C   1 
ATOM   1531 O O   . GLY   A 1 190 ? 146.648 150.431 130.169 1.00 63.97  ? 215 GLY   A O   1 
ATOM   1532 N N   . VAL   A 1 191 ? 148.008 150.386 131.954 1.00 55.74  ? 216 VAL   A N   1 
ATOM   1533 C CA  . VAL   A 1 191 ? 149.189 150.643 131.134 1.00 52.97  ? 216 VAL   A CA  1 
ATOM   1534 C C   . VAL   A 1 191 ? 149.502 149.441 130.249 1.00 59.78  ? 216 VAL   A C   1 
ATOM   1535 O O   . VAL   A 1 191 ? 149.979 149.598 129.119 1.00 66.71  ? 216 VAL   A O   1 
ATOM   1536 C CB  . VAL   A 1 191 ? 150.389 151.041 132.013 1.00 52.93  ? 216 VAL   A CB  1 
ATOM   1537 C CG1 . VAL   A 1 191 ? 150.957 149.846 132.734 1.00 59.95  ? 216 VAL   A CG1 1 
ATOM   1538 C CG2 . VAL   A 1 191 ? 151.460 151.711 131.172 1.00 54.70  ? 216 VAL   A CG2 1 
ATOM   1539 N N   . LYS   A 1 192 ? 149.250 148.225 130.742 1.00 61.36  ? 217 LYS   A N   1 
ATOM   1540 C CA  . LYS   A 1 192 ? 149.439 147.042 129.909 1.00 57.38  ? 217 LYS   A CA  1 
ATOM   1541 C C   . LYS   A 1 192 ? 148.499 147.042 128.712 1.00 61.37  ? 217 LYS   A C   1 
ATOM   1542 O O   . LYS   A 1 192 ? 148.830 146.469 127.669 1.00 68.12  ? 217 LYS   A O   1 
ATOM   1543 C CB  . LYS   A 1 192 ? 149.228 145.775 130.736 1.00 57.06  ? 217 LYS   A CB  1 
ATOM   1544 C CG  . LYS   A 1 192 ? 150.367 145.440 131.682 1.00 60.60  ? 217 LYS   A CG  1 
ATOM   1545 C CD  . LYS   A 1 192 ? 151.562 144.868 130.947 1.00 62.07  ? 217 LYS   A CD  1 
ATOM   1546 C CE  . LYS   A 1 192 ? 152.592 144.324 131.917 1.00 68.95  ? 217 LYS   A CE  1 
ATOM   1547 N NZ  . LYS   A 1 192 ? 153.802 143.816 131.220 1.00 72.06  ? 217 LYS   A NZ  1 
ATOM   1548 N N   . LYS   A 1 193 ? 147.333 147.669 128.840 1.00 59.67  ? 218 LYS   A N   1 
ATOM   1549 C CA  . LYS   A 1 193 ? 146.353 147.726 127.765 1.00 58.01  ? 218 LYS   A CA  1 
ATOM   1550 C C   . LYS   A 1 193 ? 146.628 148.839 126.761 1.00 60.19  ? 218 LYS   A C   1 
ATOM   1551 O O   . LYS   A 1 193 ? 145.813 149.043 125.856 1.00 67.88  ? 218 LYS   A O   1 
ATOM   1552 C CB  . LYS   A 1 193 ? 144.948 147.879 128.351 1.00 61.41  ? 218 LYS   A CB  1 
ATOM   1553 C CG  . LYS   A 1 193 ? 144.409 146.595 128.954 1.00 65.14  ? 218 LYS   A CG  1 
ATOM   1554 C CD  . LYS   A 1 193 ? 143.015 146.777 129.513 1.00 65.96  ? 218 LYS   A CD  1 
ATOM   1555 C CE  . LYS   A 1 193 ? 142.489 145.489 130.116 1.00 67.57  ? 218 LYS   A CE  1 
ATOM   1556 N NZ  . LYS   A 1 193 ? 143.271 145.061 131.305 1.00 68.76  ? 218 LYS   A NZ  1 
ATOM   1557 N N   . LEU   A 1 194 ? 147.742 149.560 126.887 1.00 60.52  ? 219 LEU   A N   1 
ATOM   1558 C CA  . LEU   A 1 194 ? 148.187 150.496 125.853 1.00 60.35  ? 219 LEU   A CA  1 
ATOM   1559 C C   . LEU   A 1 194 ? 149.003 149.754 124.793 1.00 63.78  ? 219 LEU   A C   1 
ATOM   1560 O O   . LEU   A 1 194 ? 150.170 150.047 124.538 1.00 70.67  ? 219 LEU   A O   1 
ATOM   1561 C CB  . LEU   A 1 194 ? 148.992 151.632 126.473 1.00 59.13  ? 219 LEU   A CB  1 
ATOM   1562 C CG  . LEU   A 1 194 ? 148.243 152.678 127.298 1.00 61.86  ? 219 LEU   A CG  1 
ATOM   1563 C CD1 . LEU   A 1 194 ? 149.233 153.596 127.981 1.00 64.36  ? 219 LEU   A CD1 1 
ATOM   1564 C CD2 . LEU   A 1 194 ? 147.295 153.482 126.432 1.00 66.02  ? 219 LEU   A CD2 1 
ATOM   1565 N N   . ASP   A 1 195 ? 148.353 148.771 124.178 1.00 66.34  ? 220 ASP   A N   1 
ATOM   1566 C CA  . ASP   A 1 195 ? 148.936 147.931 123.146 1.00 67.48  ? 220 ASP   A CA  1 
ATOM   1567 C C   . ASP   A 1 195 ? 148.162 148.134 121.852 1.00 69.13  ? 220 ASP   A C   1 
ATOM   1568 O O   . ASP   A 1 195 ? 147.005 148.562 121.857 1.00 70.28  ? 220 ASP   A O   1 
ATOM   1569 C CB  . ASP   A 1 195 ? 148.912 146.453 123.561 1.00 65.82  ? 220 ASP   A CB  1 
ATOM   1570 C CG  . ASP   A 1 195 ? 149.786 145.582 122.682 1.00 78.21  ? 220 ASP   A CG  1 
ATOM   1571 O OD1 . ASP   A 1 195 ? 150.362 146.099 121.703 1.00 81.39  ? 220 ASP   A OD1 1 
ATOM   1572 O OD2 . ASP   A 1 195 ? 149.898 144.373 122.973 1.00 85.40  ? 220 ASP   A OD2 1 
ATOM   1573 N N   . ALA   A 1 196 ? 148.818 147.830 120.733 1.00 68.98  ? 221 ALA   A N   1 
ATOM   1574 C CA  . ALA   A 1 196 ? 148.200 148.047 119.433 1.00 70.03  ? 221 ALA   A CA  1 
ATOM   1575 C C   . ALA   A 1 196 ? 146.969 147.178 119.213 1.00 72.08  ? 221 ALA   A C   1 
ATOM   1576 O O   . ALA   A 1 196 ? 146.113 147.541 118.401 1.00 78.10  ? 221 ALA   A O   1 
ATOM   1577 C CB  . ALA   A 1 196 ? 149.217 147.788 118.323 1.00 74.43  ? 221 ALA   A CB  1 
ATOM   1578 N N   . ASP   A 1 197 ? 146.855 146.050 119.911 1.00 67.57  ? 222 ASP   A N   1 
ATOM   1579 C CA  . ASP   A 1 197 ? 145.743 145.129 119.724 1.00 67.38  ? 222 ASP   A CA  1 
ATOM   1580 C C   . ASP   A 1 197 ? 144.562 145.411 120.643 1.00 70.21  ? 222 ASP   A C   1 
ATOM   1581 O O   . ASP   A 1 197 ? 143.526 144.754 120.502 1.00 74.74  ? 222 ASP   A O   1 
ATOM   1582 C CB  . ASP   A 1 197 ? 146.214 143.688 119.929 1.00 71.51  ? 222 ASP   A CB  1 
ATOM   1583 C CG  . ASP   A 1 197 ? 147.141 143.220 118.830 1.00 77.98  ? 222 ASP   A CG  1 
ATOM   1584 O OD1 . ASP   A 1 197 ? 147.580 144.067 118.024 1.00 80.76  ? 222 ASP   A OD1 1 
ATOM   1585 O OD2 . ASP   A 1 197 ? 147.426 142.008 118.764 1.00 78.40  ? 222 ASP   A OD2 1 
ATOM   1586 N N   . TRP   A 1 198 ? 144.685 146.359 121.572 1.00 70.69  ? 223 TRP   A N   1 
ATOM   1587 C CA  . TRP   A 1 198 ? 143.575 146.805 122.408 1.00 68.00  ? 223 TRP   A CA  1 
ATOM   1588 C C   . TRP   A 1 198 ? 143.028 148.158 121.993 1.00 69.89  ? 223 TRP   A C   1 
ATOM   1589 O O   . TRP   A 1 198 ? 141.819 148.376 122.066 1.00 73.68  ? 223 TRP   A O   1 
ATOM   1590 C CB  . TRP   A 1 198 ? 144.008 146.872 123.876 1.00 65.38  ? 223 TRP   A CB  1 
ATOM   1591 C CG  . TRP   A 1 198 ? 142.898 147.250 124.806 1.00 61.45  ? 223 TRP   A CG  1 
ATOM   1592 C CD1 . TRP   A 1 198 ? 142.570 148.504 125.219 1.00 64.69  ? 223 TRP   A CD1 1 
ATOM   1593 C CD2 . TRP   A 1 198 ? 141.972 146.366 125.438 1.00 58.12  ? 223 TRP   A CD2 1 
ATOM   1594 N NE1 . TRP   A 1 198 ? 141.496 148.458 126.067 1.00 69.16  ? 223 TRP   A NE1 1 
ATOM   1595 C CE2 . TRP   A 1 198 ? 141.109 147.153 126.218 1.00 61.01  ? 223 TRP   A CE2 1 
ATOM   1596 C CE3 . TRP   A 1 198 ? 141.787 144.983 125.420 1.00 63.90  ? 223 TRP   A CE3 1 
ATOM   1597 C CZ2 . TRP   A 1 198 ? 140.081 146.606 126.972 1.00 65.18  ? 223 TRP   A CZ2 1 
ATOM   1598 C CZ3 . TRP   A 1 198 ? 140.766 144.446 126.168 1.00 67.44  ? 223 TRP   A CZ3 1 
ATOM   1599 C CH2 . TRP   A 1 198 ? 139.926 145.253 126.934 1.00 68.06  ? 223 TRP   A CH2 1 
ATOM   1600 N N   . VAL   A 1 199 ? 143.892 149.079 121.563 1.00 67.77  ? 224 VAL   A N   1 
ATOM   1601 C CA  . VAL   A 1 199 ? 143.433 150.391 121.116 1.00 66.88  ? 224 VAL   A CA  1 
ATOM   1602 C C   . VAL   A 1 199 ? 142.869 150.374 119.705 1.00 71.99  ? 224 VAL   A C   1 
ATOM   1603 O O   . VAL   A 1 199 ? 142.212 151.343 119.306 1.00 77.55  ? 224 VAL   A O   1 
ATOM   1604 C CB  . VAL   A 1 199 ? 144.576 151.422 121.189 1.00 67.38  ? 224 VAL   A CB  1 
ATOM   1605 C CG1 . VAL   A 1 199 ? 145.193 151.432 122.575 1.00 69.19  ? 224 VAL   A CG1 1 
ATOM   1606 C CG2 . VAL   A 1 199 ? 145.634 151.140 120.126 1.00 70.16  ? 224 VAL   A CG2 1 
ATOM   1607 N N   . GLU   A 1 200 ? 143.098 149.302 118.942 1.00 69.26  ? 225 GLU   A N   1 
ATOM   1608 C CA  . GLU   A 1 200 ? 142.608 149.184 117.575 1.00 67.05  ? 225 GLU   A CA  1 
ATOM   1609 C C   . GLU   A 1 200 ? 141.392 148.277 117.440 1.00 70.88  ? 225 GLU   A C   1 
ATOM   1610 O O   . GLU   A 1 200 ? 140.870 148.140 116.329 1.00 78.02  ? 225 GLU   A O   1 
ATOM   1611 C CB  . GLU   A 1 200 ? 143.724 148.667 116.662 1.00 70.08  ? 225 GLU   A CB  1 
ATOM   1612 C CG  . GLU   A 1 200 ? 144.908 149.612 116.551 1.00 75.94  ? 225 GLU   A CG  1 
ATOM   1613 C CD  . GLU   A 1 200 ? 146.022 149.058 115.688 1.00 84.93  ? 225 GLU   A CD  1 
ATOM   1614 O OE1 . GLU   A 1 200 ? 146.041 147.834 115.448 1.00 84.24  ? 225 GLU   A OE1 1 
ATOM   1615 O OE2 . GLU   A 1 200 ? 146.881 149.850 115.247 1.00 87.70  ? 225 GLU   A OE2 1 
ATOM   1616 N N   . GLY   A 1 201 ? 140.936 147.651 118.523 1.00 69.40  ? 226 GLY   A N   1 
ATOM   1617 C CA  . GLY   A 1 201 ? 139.679 146.929 118.505 1.00 71.59  ? 226 GLY   A CA  1 
ATOM   1618 C C   . GLY   A 1 201 ? 139.765 145.448 118.224 1.00 75.08  ? 226 GLY   A C   1 
ATOM   1619 O O   . GLY   A 1 201 ? 138.731 144.836 117.932 1.00 80.58  ? 226 GLY   A O   1 
ATOM   1620 N N   . TYR   A 1 202 ? 140.954 144.844 118.304 1.00 68.82  ? 227 TYR   A N   1 
ATOM   1621 C CA  . TYR   A 1 202 ? 141.097 143.441 117.929 1.00 65.47  ? 227 TYR   A CA  1 
ATOM   1622 C C   . TYR   A 1 202 ? 140.797 142.508 119.097 1.00 66.77  ? 227 TYR   A C   1 
ATOM   1623 O O   . TYR   A 1 202 ? 140.035 141.548 118.950 1.00 72.64  ? 227 TYR   A O   1 
ATOM   1624 C CB  . TYR   A 1 202 ? 142.499 143.190 117.382 1.00 66.60  ? 227 TYR   A CB  1 
ATOM   1625 C CG  . TYR   A 1 202 ? 142.752 143.868 116.059 1.00 67.64  ? 227 TYR   A CG  1 
ATOM   1626 C CD1 . TYR   A 1 202 ? 142.115 143.442 114.907 1.00 60.92  ? 227 TYR   A CD1 1 
ATOM   1627 C CD2 . TYR   A 1 202 ? 143.634 144.931 115.961 1.00 73.85  ? 227 TYR   A CD2 1 
ATOM   1628 C CE1 . TYR   A 1 202 ? 142.341 144.058 113.699 1.00 63.23  ? 227 TYR   A CE1 1 
ATOM   1629 C CE2 . TYR   A 1 202 ? 143.868 145.551 114.754 1.00 70.57  ? 227 TYR   A CE2 1 
ATOM   1630 C CZ  . TYR   A 1 202 ? 143.219 145.112 113.627 1.00 67.90  ? 227 TYR   A CZ  1 
ATOM   1631 O OH  . TYR   A 1 202 ? 143.451 145.729 112.421 1.00 69.56  ? 227 TYR   A OH  1 
ATOM   1632 N N   . SER   A 1 203 ? 141.388 142.761 120.259 1.00 64.03  ? 228 SER   A N   1 
ATOM   1633 C CA  . SER   A 1 203 ? 141.093 141.942 121.425 1.00 63.63  ? 228 SER   A CA  1 
ATOM   1634 C C   . SER   A 1 203 ? 139.668 142.195 121.893 1.00 71.00  ? 228 SER   A C   1 
ATOM   1635 O O   . SER   A 1 203 ? 139.227 143.342 121.983 1.00 80.93  ? 228 SER   A O   1 
ATOM   1636 C CB  . SER   A 1 203 ? 142.077 142.246 122.551 1.00 68.12  ? 228 SER   A CB  1 
ATOM   1637 O OG  . SER   A 1 203 ? 143.404 141.946 122.157 1.00 73.81  ? 228 SER   A OG  1 
ATOM   1638 N N   . MET   A 1 204 ? 138.948 141.116 122.199 1.00 71.12  ? 229 MET   A N   1 
ATOM   1639 C CA  . MET   A 1 204 ? 137.537 141.196 122.585 1.00 74.56  ? 229 MET   A CA  1 
ATOM   1640 C C   . MET   A 1 204 ? 136.708 141.887 121.504 1.00 76.78  ? 229 MET   A C   1 
ATOM   1641 O O   . MET   A 1 204 ? 135.912 142.785 121.783 1.00 77.24  ? 229 MET   A O   1 
ATOM   1642 C CB  . MET   A 1 204 ? 137.364 141.908 123.929 1.00 75.71  ? 229 MET   A CB  1 
ATOM   1643 C CG  . MET   A 1 204 ? 137.895 141.142 125.122 1.00 79.50  ? 229 MET   A CG  1 
ATOM   1644 S SD  . MET   A 1 204 ? 138.218 142.196 126.552 1.00 95.72  ? 229 MET   A SD  1 
ATOM   1645 C CE  . MET   A 1 204 ? 136.869 143.372 126.464 1.00 77.33  ? 229 MET   A CE  1 
ATOM   1646 N N   . GLU   A 1 205 ? 136.903 141.473 120.254 1.00 76.73  ? 230 GLU   A N   1 
ATOM   1647 C CA  . GLU   A 1 205 ? 136.165 142.065 119.147 1.00 80.90  ? 230 GLU   A CA  1 
ATOM   1648 C C   . GLU   A 1 205 ? 134.720 141.594 119.079 1.00 85.95  ? 230 GLU   A C   1 
ATOM   1649 O O   . GLU   A 1 205 ? 133.897 142.272 118.455 1.00 87.89  ? 230 GLU   A O   1 
ATOM   1650 C CB  . GLU   A 1 205 ? 136.869 141.748 117.825 1.00 87.25  ? 230 GLU   A CB  1 
ATOM   1651 C CG  . GLU   A 1 205 ? 136.307 142.486 116.619 1.00 97.98  ? 230 GLU   A CG  1 
ATOM   1652 C CD  . GLU   A 1 205 ? 137.132 142.266 115.364 1.00 105.80 ? 230 GLU   A CD  1 
ATOM   1653 O OE1 . GLU   A 1 205 ? 138.119 141.504 115.424 1.00 101.13 ? 230 GLU   A OE1 1 
ATOM   1654 O OE2 . GLU   A 1 205 ? 136.791 142.857 114.318 1.00 108.95 ? 230 GLU   A OE2 1 
ATOM   1655 N N   . TYR   A 1 206 ? 134.389 140.467 119.713 1.00 86.32  ? 231 TYR   A N   1 
ATOM   1656 C CA  . TYR   A 1 206 ? 133.067 139.858 119.615 1.00 83.72  ? 231 TYR   A CA  1 
ATOM   1657 C C   . TYR   A 1 206 ? 132.267 139.954 120.907 1.00 78.39  ? 231 TYR   A C   1 
ATOM   1658 O O   . TYR   A 1 206 ? 131.245 139.273 121.037 1.00 82.73  ? 231 TYR   A O   1 
ATOM   1659 C CB  . TYR   A 1 206 ? 133.196 138.388 119.205 1.00 88.26  ? 231 TYR   A CB  1 
ATOM   1660 C CG  . TYR   A 1 206 ? 133.962 138.143 117.917 1.00 101.20 ? 231 TYR   A CG  1 
ATOM   1661 C CD1 . TYR   A 1 206 ? 133.921 139.054 116.866 1.00 102.19 ? 231 TYR   A CD1 1 
ATOM   1662 C CD2 . TYR   A 1 206 ? 134.723 136.993 117.751 1.00 105.23 ? 231 TYR   A CD2 1 
ATOM   1663 C CE1 . TYR   A 1 206 ? 134.618 138.827 115.694 1.00 103.52 ? 231 TYR   A CE1 1 
ATOM   1664 C CE2 . TYR   A 1 206 ? 135.424 136.758 116.582 1.00 113.07 ? 231 TYR   A CE2 1 
ATOM   1665 C CZ  . TYR   A 1 206 ? 135.367 137.679 115.558 1.00 113.46 ? 231 TYR   A CZ  1 
ATOM   1666 O OH  . TYR   A 1 206 ? 136.062 137.449 114.392 1.00 108.39 ? 231 TYR   A OH  1 
ATOM   1667 N N   . LEU   A 1 207 ? 132.696 140.776 121.863 1.00 73.72  ? 232 LEU   A N   1 
ATOM   1668 C CA  . LEU   A 1 207 ? 131.983 140.935 123.124 1.00 69.62  ? 232 LEU   A CA  1 
ATOM   1669 C C   . LEU   A 1 207 ? 130.922 142.027 123.073 1.00 72.09  ? 232 LEU   A C   1 
ATOM   1670 O O   . LEU   A 1 207 ? 130.170 142.181 124.040 1.00 74.80  ? 232 LEU   A O   1 
ATOM   1671 C CB  . LEU   A 1 207 ? 132.979 141.239 124.248 1.00 70.89  ? 232 LEU   A CB  1 
ATOM   1672 C CG  . LEU   A 1 207 ? 132.520 141.052 125.698 1.00 73.37  ? 232 LEU   A CG  1 
ATOM   1673 C CD1 . LEU   A 1 207 ? 132.176 139.597 125.996 1.00 73.17  ? 232 LEU   A CD1 1 
ATOM   1674 C CD2 . LEU   A 1 207 ? 133.589 141.556 126.648 1.00 75.24  ? 232 LEU   A CD2 1 
ATOM   1675 N N   . SER   A 1 208 ? 130.826 142.773 121.975 1.00 76.62  ? 233 SER   A N   1 
ATOM   1676 C CA  . SER   A 1 208 ? 129.840 143.839 121.860 1.00 78.21  ? 233 SER   A CA  1 
ATOM   1677 C C   . SER   A 1 208 ? 128.465 143.338 121.437 1.00 76.62  ? 233 SER   A C   1 
ATOM   1678 O O   . SER   A 1 208 ? 127.533 144.144 121.357 1.00 82.69  ? 233 SER   A O   1 
ATOM   1679 C CB  . SER   A 1 208 ? 130.330 144.893 120.865 1.00 80.75  ? 233 SER   A CB  1 
ATOM   1680 O OG  . SER   A 1 208 ? 129.408 145.962 120.751 1.00 84.38  ? 233 SER   A OG  1 
ATOM   1681 N N   . ARG   A 1 209 ? 128.314 142.043 121.165 1.00 72.82  ? 234 ARG   A N   1 
ATOM   1682 C CA  . ARG   A 1 209 ? 127.030 141.469 120.794 1.00 75.38  ? 234 ARG   A CA  1 
ATOM   1683 C C   . ARG   A 1 209 ? 126.208 141.019 121.994 1.00 71.31  ? 234 ARG   A C   1 
ATOM   1684 O O   . ARG   A 1 209 ? 125.051 140.626 121.817 1.00 75.35  ? 234 ARG   A O   1 
ATOM   1685 C CB  . ARG   A 1 209 ? 127.247 140.281 119.851 1.00 86.02  ? 234 ARG   A CB  1 
ATOM   1686 C CG  . ARG   A 1 209 ? 128.006 140.641 118.579 1.00 95.17  ? 234 ARG   A CG  1 
ATOM   1687 C CD  . ARG   A 1 209 ? 128.198 139.438 117.671 1.00 99.54  ? 234 ARG   A CD  1 
ATOM   1688 N NE  . ARG   A 1 209 ? 128.998 139.767 116.497 1.00 104.04 ? 234 ARG   A NE  1 
ATOM   1689 C CZ  . ARG   A 1 209 ? 129.353 138.905 115.552 1.00 108.42 ? 234 ARG   A CZ  1 
ATOM   1690 N NH1 . ARG   A 1 209 ? 128.996 137.630 115.602 1.00 109.77 ? 234 ARG   A NH1 1 
ATOM   1691 N NH2 . ARG   A 1 209 ? 130.089 139.332 114.530 1.00 109.20 ? 234 ARG   A NH2 1 
ATOM   1692 N N   . HIS   A 1 210 ? 126.769 141.063 123.199 1.00 67.36  ? 235 HIS   A N   1 
ATOM   1693 C CA  . HIS   A 1 210 ? 126.024 140.688 124.391 1.00 63.81  ? 235 HIS   A CA  1 
ATOM   1694 C C   . HIS   A 1 210 ? 124.876 141.662 124.621 1.00 66.15  ? 235 HIS   A C   1 
ATOM   1695 O O   . HIS   A 1 210 ? 124.977 142.857 124.333 1.00 73.39  ? 235 HIS   A O   1 
ATOM   1696 C CB  . HIS   A 1 210 ? 126.952 140.671 125.603 1.00 66.82  ? 235 HIS   A CB  1 
ATOM   1697 C CG  . HIS   A 1 210 ? 126.528 139.722 126.677 1.00 68.93  ? 235 HIS   A CG  1 
ATOM   1698 N ND1 . HIS   A 1 210 ? 125.462 139.971 127.513 1.00 74.96  ? 235 HIS   A ND1 1 
ATOM   1699 C CD2 . HIS   A 1 210 ? 127.036 138.529 127.061 1.00 70.46  ? 235 HIS   A CD2 1 
ATOM   1700 C CE1 . HIS   A 1 210 ? 125.328 138.968 128.361 1.00 75.84  ? 235 HIS   A CE1 1 
ATOM   1701 N NE2 . HIS   A 1 210 ? 126.270 138.080 128.108 1.00 74.55  ? 235 HIS   A NE2 1 
ATOM   1702 N N   . TRP   A 1 211 ? 123.766 141.138 125.142 1.00 64.04  ? 236 TRP   A N   1 
ATOM   1703 C CA  . TRP   A 1 211 ? 122.576 141.960 125.331 1.00 68.00  ? 236 TRP   A CA  1 
ATOM   1704 C C   . TRP   A 1 211 ? 122.774 143.061 126.365 1.00 70.54  ? 236 TRP   A C   1 
ATOM   1705 O O   . TRP   A 1 211 ? 121.990 144.016 126.383 1.00 78.66  ? 236 TRP   A O   1 
ATOM   1706 C CB  . TRP   A 1 211 ? 121.384 141.086 125.723 1.00 69.87  ? 236 TRP   A CB  1 
ATOM   1707 C CG  . TRP   A 1 211 ? 121.521 140.398 127.042 1.00 71.83  ? 236 TRP   A CG  1 
ATOM   1708 C CD1 . TRP   A 1 211 ? 122.133 139.206 127.283 1.00 74.31  ? 236 TRP   A CD1 1 
ATOM   1709 C CD2 . TRP   A 1 211 ? 121.020 140.853 128.302 1.00 74.69  ? 236 TRP   A CD2 1 
ATOM   1710 N NE1 . TRP   A 1 211 ? 122.052 138.892 128.615 1.00 72.83  ? 236 TRP   A NE1 1 
ATOM   1711 C CE2 . TRP   A 1 211 ? 121.371 139.888 129.263 1.00 74.03  ? 236 TRP   A CE2 1 
ATOM   1712 C CE3 . TRP   A 1 211 ? 120.310 141.985 128.710 1.00 80.28  ? 236 TRP   A CE3 1 
ATOM   1713 C CZ2 . TRP   A 1 211 ? 121.041 140.020 130.607 1.00 79.90  ? 236 TRP   A CZ2 1 
ATOM   1714 C CZ3 . TRP   A 1 211 ? 119.982 142.114 130.045 1.00 82.82  ? 236 TRP   A CZ3 1 
ATOM   1715 C CH2 . TRP   A 1 211 ? 120.347 141.137 130.978 1.00 83.61  ? 236 TRP   A CH2 1 
ATOM   1716 N N   . LEU   A 1 212 ? 123.789 142.957 127.227 1.00 68.01  ? 237 LEU   A N   1 
ATOM   1717 C CA  . LEU   A 1 212 ? 124.019 144.005 128.216 1.00 67.70  ? 237 LEU   A CA  1 
ATOM   1718 C C   . LEU   A 1 212 ? 124.398 145.324 127.559 1.00 70.27  ? 237 LEU   A C   1 
ATOM   1719 O O   . LEU   A 1 212 ? 124.148 146.392 128.128 1.00 73.73  ? 237 LEU   A O   1 
ATOM   1720 C CB  . LEU   A 1 212 ? 125.110 143.575 129.197 1.00 71.93  ? 237 LEU   A CB  1 
ATOM   1721 C CG  . LEU   A 1 212 ? 124.811 142.358 130.074 1.00 76.61  ? 237 LEU   A CG  1 
ATOM   1722 C CD1 . LEU   A 1 212 ? 126.040 141.956 130.866 1.00 75.76  ? 237 LEU   A CD1 1 
ATOM   1723 C CD2 . LEU   A 1 212 ? 123.649 142.630 131.011 1.00 77.30  ? 237 LEU   A CD2 1 
ATOM   1724 N N   . PHE   A 1 213 ? 124.998 145.277 126.372 1.00 68.15  ? 238 PHE   A N   1 
ATOM   1725 C CA  . PHE   A 1 213 ? 125.330 146.472 125.610 1.00 70.99  ? 238 PHE   A CA  1 
ATOM   1726 C C   . PHE   A 1 213 ? 124.181 146.948 124.728 1.00 74.83  ? 238 PHE   A C   1 
ATOM   1727 O O   . PHE   A 1 213 ? 124.387 147.834 123.892 1.00 80.84  ? 238 PHE   A O   1 
ATOM   1728 C CB  . PHE   A 1 213 ? 126.567 146.217 124.746 1.00 72.08  ? 238 PHE   A CB  1 
ATOM   1729 C CG  . PHE   A 1 213 ? 127.821 145.984 125.533 1.00 72.33  ? 238 PHE   A CG  1 
ATOM   1730 C CD1 . PHE   A 1 213 ? 128.623 147.041 125.910 1.00 73.99  ? 238 PHE   A CD1 1 
ATOM   1731 C CD2 . PHE   A 1 213 ? 128.201 144.707 125.890 1.00 73.77  ? 238 PHE   A CD2 1 
ATOM   1732 C CE1 . PHE   A 1 213 ? 129.775 146.827 126.629 1.00 71.40  ? 238 PHE   A CE1 1 
ATOM   1733 C CE2 . PHE   A 1 213 ? 129.354 144.492 126.611 1.00 72.61  ? 238 PHE   A CE2 1 
ATOM   1734 C CZ  . PHE   A 1 213 ? 130.141 145.552 126.979 1.00 68.42  ? 238 PHE   A CZ  1 
ATOM   1735 N N   . SER   A 1 214 ? 122.988 146.371 124.882 1.00 69.92  ? 239 SER   A N   1 
ATOM   1736 C CA  . SER   A 1 214 ? 121.852 146.767 124.055 1.00 67.24  ? 239 SER   A CA  1 
ATOM   1737 C C   . SER   A 1 214 ? 121.523 148.258 124.097 1.00 71.29  ? 239 SER   A C   1 
ATOM   1738 O O   . SER   A 1 214 ? 121.272 148.822 123.018 1.00 79.05  ? 239 SER   A O   1 
ATOM   1739 C CB  . SER   A 1 214 ? 120.623 145.935 124.446 1.00 72.34  ? 239 SER   A CB  1 
ATOM   1740 O OG  . SER   A 1 214 ? 120.402 145.940 125.844 1.00 78.61  ? 239 SER   A OG  1 
ATOM   1741 N N   . PRO   A 1 215 ? 121.472 148.946 125.251 1.00 65.96  ? 240 PRO   A N   1 
ATOM   1742 C CA  . PRO   A 1 215 ? 121.128 150.380 125.195 1.00 70.20  ? 240 PRO   A CA  1 
ATOM   1743 C C   . PRO   A 1 215 ? 122.109 151.218 124.396 1.00 74.67  ? 240 PRO   A C   1 
ATOM   1744 O O   . PRO   A 1 215 ? 121.692 152.149 123.694 1.00 82.47  ? 240 PRO   A O   1 
ATOM   1745 C CB  . PRO   A 1 215 ? 121.095 150.794 126.672 1.00 71.81  ? 240 PRO   A CB  1 
ATOM   1746 C CG  . PRO   A 1 215 ? 121.881 149.787 127.372 1.00 72.49  ? 240 PRO   A CG  1 
ATOM   1747 C CD  . PRO   A 1 215 ? 121.652 148.511 126.649 1.00 70.50  ? 240 PRO   A CD  1 
ATOM   1748 N N   . PHE   A 1 216 ? 123.404 150.896 124.462 1.00 73.30  ? 241 PHE   A N   1 
ATOM   1749 C CA  . PHE   A 1 216 ? 124.399 151.676 123.734 1.00 72.17  ? 241 PHE   A CA  1 
ATOM   1750 C C   . PHE   A 1 216 ? 124.149 151.642 122.235 1.00 76.77  ? 241 PHE   A C   1 
ATOM   1751 O O   . PHE   A 1 216 ? 124.488 152.598 121.529 1.00 84.28  ? 241 PHE   A O   1 
ATOM   1752 C CB  . PHE   A 1 216 ? 125.801 151.154 124.035 1.00 73.93  ? 241 PHE   A CB  1 
ATOM   1753 C CG  . PHE   A 1 216 ? 126.251 151.399 125.441 1.00 74.67  ? 241 PHE   A CG  1 
ATOM   1754 C CD1 . PHE   A 1 216 ? 125.946 150.502 126.447 1.00 77.75  ? 241 PHE   A CD1 1 
ATOM   1755 C CD2 . PHE   A 1 216 ? 126.991 152.520 125.754 1.00 76.88  ? 241 PHE   A CD2 1 
ATOM   1756 C CE1 . PHE   A 1 216 ? 126.363 150.725 127.740 1.00 81.57  ? 241 PHE   A CE1 1 
ATOM   1757 C CE2 . PHE   A 1 216 ? 127.413 152.747 127.045 1.00 82.32  ? 241 PHE   A CE2 1 
ATOM   1758 C CZ  . PHE   A 1 216 ? 127.098 151.849 128.040 1.00 83.92  ? 241 PHE   A CZ  1 
ATOM   1759 N N   . LYS   A 1 217 ? 123.558 150.560 121.730 1.00 75.53  ? 242 LYS   A N   1 
ATOM   1760 C CA  . LYS   A 1 217 ? 123.274 150.461 120.307 1.00 80.31  ? 242 LYS   A CA  1 
ATOM   1761 C C   . LYS   A 1 217 ? 122.178 151.414 119.850 1.00 82.87  ? 242 LYS   A C   1 
ATOM   1762 O O   . LYS   A 1 217 ? 122.016 151.601 118.640 1.00 82.86  ? 242 LYS   A O   1 
ATOM   1763 C CB  . LYS   A 1 217 ? 122.898 149.024 119.952 1.00 78.61  ? 242 LYS   A CB  1 
ATOM   1764 C CG  . LYS   A 1 217 ? 124.033 148.039 120.168 1.00 82.51  ? 242 LYS   A CG  1 
ATOM   1765 C CD  . LYS   A 1 217 ? 123.716 146.677 119.584 1.00 87.05  ? 242 LYS   A CD  1 
ATOM   1766 C CE  . LYS   A 1 217 ? 124.823 145.676 119.871 1.00 88.21  ? 242 LYS   A CE  1 
ATOM   1767 N NZ  . LYS   A 1 217 ? 126.127 146.093 119.292 1.00 89.46  ? 242 LYS   A NZ  1 
ATOM   1768 N N   . LEU   A 1 218 ? 121.424 152.021 120.771 1.00 82.72  ? 243 LEU   A N   1 
ATOM   1769 C CA  . LEU   A 1 218 ? 120.425 152.996 120.350 1.00 78.68  ? 243 LEU   A CA  1 
ATOM   1770 C C   . LEU   A 1 218 ? 121.071 154.240 119.757 1.00 78.23  ? 243 LEU   A C   1 
ATOM   1771 O O   . LEU   A 1 218 ? 120.478 154.882 118.883 1.00 81.25  ? 243 LEU   A O   1 
ATOM   1772 C CB  . LEU   A 1 218 ? 119.527 153.381 121.526 1.00 79.82  ? 243 LEU   A CB  1 
ATOM   1773 C CG  . LEU   A 1 218 ? 118.614 152.295 122.098 1.00 83.98  ? 243 LEU   A CG  1 
ATOM   1774 C CD1 . LEU   A 1 218 ? 117.912 152.805 123.347 1.00 84.16  ? 243 LEU   A CD1 1 
ATOM   1775 C CD2 . LEU   A 1 218 ? 117.593 151.830 121.069 1.00 83.69  ? 243 LEU   A CD2 1 
ATOM   1776 N N   . LEU   A 1 219 ? 122.281 154.589 120.209 1.00 79.97  ? 244 LEU   A N   1 
ATOM   1777 C CA  . LEU   A 1 219 ? 122.970 155.799 119.778 1.00 82.76  ? 244 LEU   A CA  1 
ATOM   1778 C C   . LEU   A 1 219 ? 124.225 155.540 118.958 1.00 85.49  ? 244 LEU   A C   1 
ATOM   1779 O O   . LEU   A 1 219 ? 124.718 156.473 118.318 1.00 88.57  ? 244 LEU   A O   1 
ATOM   1780 C CB  . LEU   A 1 219 ? 123.359 156.654 120.995 1.00 83.50  ? 244 LEU   A CB  1 
ATOM   1781 C CG  . LEU   A 1 219 ? 122.269 157.340 121.834 1.00 90.87  ? 244 LEU   A CG  1 
ATOM   1782 C CD1 . LEU   A 1 219 ? 121.369 158.222 120.974 1.00 89.73  ? 244 LEU   A CD1 1 
ATOM   1783 C CD2 . LEU   A 1 219 ? 121.438 156.337 122.627 1.00 87.14  ? 244 LEU   A CD2 1 
ATOM   1784 N N   . LEU   A 1 220 ? 124.750 154.314 118.959 1.00 84.34  ? 245 LEU   A N   1 
ATOM   1785 C CA  . LEU   A 1 220 ? 125.997 153.985 118.284 1.00 83.62  ? 245 LEU   A CA  1 
ATOM   1786 C C   . LEU   A 1 220 ? 125.831 152.715 117.464 1.00 85.88  ? 245 LEU   A C   1 
ATOM   1787 O O   . LEU   A 1 220 ? 125.044 151.831 117.807 1.00 88.37  ? 245 LEU   A O   1 
ATOM   1788 C CB  . LEU   A 1 220 ? 127.140 153.793 119.287 1.00 81.75  ? 245 LEU   A CB  1 
ATOM   1789 C CG  . LEU   A 1 220 ? 127.498 154.995 120.161 1.00 84.16  ? 245 LEU   A CG  1 
ATOM   1790 C CD1 . LEU   A 1 220 ? 128.533 154.595 121.196 1.00 85.18  ? 245 LEU   A CD1 1 
ATOM   1791 C CD2 . LEU   A 1 220 ? 128.009 156.153 119.318 1.00 84.65  ? 245 LEU   A CD2 1 
ATOM   1792 N N   . SER   A 1 221 ? 126.583 152.637 116.369 1.00 84.39  ? 246 SER   A N   1 
ATOM   1793 C CA  . SER   A 1 221 ? 126.634 151.423 115.574 1.00 80.63  ? 246 SER   A CA  1 
ATOM   1794 C C   . SER   A 1 221 ? 127.449 150.352 116.297 1.00 82.65  ? 246 SER   A C   1 
ATOM   1795 O O   . SER   A 1 221 ? 128.168 150.622 117.263 1.00 88.37  ? 246 SER   A O   1 
ATOM   1796 C CB  . SER   A 1 221 ? 127.236 151.709 114.200 1.00 86.88  ? 246 SER   A CB  1 
ATOM   1797 O OG  . SER   A 1 221 ? 128.552 152.220 114.317 1.00 90.74  ? 246 SER   A OG  1 
ATOM   1798 N N   . GLU   A 1 222 ? 127.321 149.114 115.817 1.00 85.01  ? 247 GLU   A N   1 
ATOM   1799 C CA  . GLU   A 1 222 ? 128.020 147.999 116.449 1.00 89.60  ? 247 GLU   A CA  1 
ATOM   1800 C C   . GLU   A 1 222 ? 129.531 148.167 116.356 1.00 87.92  ? 247 GLU   A C   1 
ATOM   1801 O O   . GLU   A 1 222 ? 130.254 147.869 117.314 1.00 88.24  ? 247 GLU   A O   1 
ATOM   1802 C CB  . GLU   A 1 222 ? 127.586 146.681 115.808 1.00 93.45  ? 247 GLU   A CB  1 
ATOM   1803 C CG  . GLU   A 1 222 ? 128.172 145.441 116.470 1.00 97.30  ? 247 GLU   A CG  1 
ATOM   1804 C CD  . GLU   A 1 222 ? 127.610 144.153 115.899 1.00 106.73 ? 247 GLU   A CD  1 
ATOM   1805 O OE1 . GLU   A 1 222 ? 126.716 144.223 115.029 1.00 109.59 ? 247 GLU   A OE1 1 
ATOM   1806 O OE2 . GLU   A 1 222 ? 128.065 143.068 116.320 1.00 105.80 ? 247 GLU   A OE2 1 
ATOM   1807 N N   . GLU   A 1 223 ? 130.028 148.628 115.207 1.00 84.14  ? 248 GLU   A N   1 
ATOM   1808 C CA  . GLU   A 1 223 ? 131.468 148.805 115.046 1.00 86.03  ? 248 GLU   A CA  1 
ATOM   1809 C C   . GLU   A 1 223 ? 132.011 149.851 116.012 1.00 84.61  ? 248 GLU   A C   1 
ATOM   1810 O O   . GLU   A 1 223 ? 133.079 149.660 116.605 1.00 84.83  ? 248 GLU   A O   1 
ATOM   1811 C CB  . GLU   A 1 223 ? 131.800 149.175 113.597 1.00 93.08  ? 248 GLU   A CB  1 
ATOM   1812 C CG  . GLU   A 1 223 ? 131.102 150.420 113.054 1.00 97.14  ? 248 GLU   A CG  1 
ATOM   1813 C CD  . GLU   A 1 223 ? 131.464 150.701 111.609 1.00 105.02 ? 248 GLU   A CD  1 
ATOM   1814 O OE1 . GLU   A 1 223 ? 132.291 149.954 111.046 1.00 107.16 ? 248 GLU   A OE1 1 
ATOM   1815 O OE2 . GLU   A 1 223 ? 130.921 151.669 111.036 1.00 107.76 ? 248 GLU   A OE2 1 
ATOM   1816 N N   . LEU   A 1 224 ? 131.295 150.964 116.188 1.00 81.97  ? 249 LEU   A N   1 
ATOM   1817 C CA  . LEU   A 1 224 ? 131.739 151.983 117.133 1.00 80.18  ? 249 LEU   A CA  1 
ATOM   1818 C C   . LEU   A 1 224 ? 131.499 151.568 118.578 1.00 81.87  ? 249 LEU   A C   1 
ATOM   1819 O O   . LEU   A 1 224 ? 132.285 151.934 119.458 1.00 84.72  ? 249 LEU   A O   1 
ATOM   1820 C CB  . LEU   A 1 224 ? 131.034 153.313 116.864 1.00 80.87  ? 249 LEU   A CB  1 
ATOM   1821 C CG  . LEU   A 1 224 ? 131.782 154.299 115.970 1.00 84.11  ? 249 LEU   A CG  1 
ATOM   1822 C CD1 . LEU   A 1 224 ? 131.923 153.756 114.561 1.00 85.52  ? 249 LEU   A CD1 1 
ATOM   1823 C CD2 . LEU   A 1 224 ? 131.072 155.641 115.961 1.00 83.46  ? 249 LEU   A CD2 1 
ATOM   1824 N N   . THR   A 1 225 ? 130.427 150.819 118.844 1.00 79.60  ? 250 THR   A N   1 
ATOM   1825 C CA  . THR   A 1 225 ? 130.162 150.374 120.207 1.00 76.27  ? 250 THR   A CA  1 
ATOM   1826 C C   . THR   A 1 225 ? 131.241 149.424 120.705 1.00 78.08  ? 250 THR   A C   1 
ATOM   1827 O O   . THR   A 1 225 ? 131.510 149.372 121.910 1.00 80.14  ? 250 THR   A O   1 
ATOM   1828 C CB  . THR   A 1 225 ? 128.794 149.699 120.284 1.00 84.06  ? 250 THR   A CB  1 
ATOM   1829 O OG1 . THR   A 1 225 ? 127.775 150.632 119.907 1.00 86.02  ? 250 THR   A OG1 1 
ATOM   1830 C CG2 . THR   A 1 225 ? 128.521 149.198 121.691 1.00 83.68  ? 250 THR   A CG2 1 
ATOM   1831 N N   . SER   A 1 226 ? 131.872 148.676 119.804 1.00 77.84  ? 251 SER   A N   1 
ATOM   1832 C CA  . SER   A 1 226 ? 132.925 147.744 120.178 1.00 76.96  ? 251 SER   A CA  1 
ATOM   1833 C C   . SER   A 1 226 ? 134.285 148.407 120.335 1.00 76.20  ? 251 SER   A C   1 
ATOM   1834 O O   . SER   A 1 226 ? 135.237 147.721 120.717 1.00 80.99  ? 251 SER   A O   1 
ATOM   1835 C CB  . SER   A 1 226 ? 133.033 146.629 119.137 1.00 79.58  ? 251 SER   A CB  1 
ATOM   1836 O OG  . SER   A 1 226 ? 134.119 145.770 119.430 1.00 81.94  ? 251 SER   A OG  1 
ATOM   1837 N N   . LEU   A 1 227 ? 134.402 149.705 120.055 1.00 73.30  ? 252 LEU   A N   1 
ATOM   1838 C CA  . LEU   A 1 227 ? 135.662 150.430 120.147 1.00 71.46  ? 252 LEU   A CA  1 
ATOM   1839 C C   . LEU   A 1 227 ? 135.633 151.501 121.223 1.00 74.83  ? 252 LEU   A C   1 
ATOM   1840 O O   . LEU   A 1 227 ? 136.531 151.543 122.073 1.00 79.15  ? 252 LEU   A O   1 
ATOM   1841 C CB  . LEU   A 1 227 ? 135.995 151.057 118.785 1.00 72.91  ? 252 LEU   A CB  1 
ATOM   1842 C CG  . LEU   A 1 227 ? 137.348 151.748 118.621 1.00 73.26  ? 252 LEU   A CG  1 
ATOM   1843 C CD1 . LEU   A 1 227 ? 138.493 150.770 118.796 1.00 72.15  ? 252 LEU   A CD1 1 
ATOM   1844 C CD2 . LEU   A 1 227 ? 137.423 152.413 117.261 1.00 73.35  ? 252 LEU   A CD2 1 
ATOM   1845 N N   . LEU   A 1 228 ? 134.625 152.374 121.214 1.00 75.42  ? 253 LEU   A N   1 
ATOM   1846 C CA  . LEU   A 1 228 ? 134.573 153.445 122.202 1.00 76.05  ? 253 LEU   A CA  1 
ATOM   1847 C C   . LEU   A 1 228 ? 134.239 152.909 123.587 1.00 78.76  ? 253 LEU   A C   1 
ATOM   1848 O O   . LEU   A 1 228 ? 134.853 153.316 124.580 1.00 81.45  ? 253 LEU   A O   1 
ATOM   1849 C CB  . LEU   A 1 228 ? 133.548 154.495 121.782 1.00 74.82  ? 253 LEU   A CB  1 
ATOM   1850 C CG  . LEU   A 1 228 ? 133.725 155.133 120.405 1.00 77.34  ? 253 LEU   A CG  1 
ATOM   1851 C CD1 . LEU   A 1 228 ? 132.591 156.100 120.133 1.00 79.24  ? 253 LEU   A CD1 1 
ATOM   1852 C CD2 . LEU   A 1 228 ? 135.064 155.841 120.297 1.00 77.92  ? 253 LEU   A CD2 1 
ATOM   1853 N N   . VAL   A 1 229 ? 133.275 151.998 123.675 1.00 73.79  ? 254 VAL   A N   1 
ATOM   1854 C CA  . VAL   A 1 229 ? 132.756 151.550 124.963 1.00 73.50  ? 254 VAL   A CA  1 
ATOM   1855 C C   . VAL   A 1 229 ? 133.540 150.361 125.498 1.00 75.79  ? 254 VAL   A C   1 
ATOM   1856 O O   . VAL   A 1 229 ? 134.014 150.378 126.637 1.00 78.49  ? 254 VAL   A O   1 
ATOM   1857 C CB  . VAL   A 1 229 ? 131.254 151.219 124.836 1.00 74.26  ? 254 VAL   A CB  1 
ATOM   1858 C CG1 . VAL   A 1 229 ? 130.705 150.721 126.168 1.00 79.74  ? 254 VAL   A CG1 1 
ATOM   1859 C CG2 . VAL   A 1 229 ? 130.480 152.437 124.349 1.00 78.78  ? 254 VAL   A CG2 1 
ATOM   1860 N N   . VAL   A 1 230 ? 133.686 149.310 124.693 1.00 69.43  ? 255 VAL   A N   1 
ATOM   1861 C CA  . VAL   A 1 230 ? 134.286 148.076 125.187 1.00 64.31  ? 255 VAL   A CA  1 
ATOM   1862 C C   . VAL   A 1 230 ? 135.778 148.261 125.429 1.00 67.04  ? 255 VAL   A C   1 
ATOM   1863 O O   . VAL   A 1 230 ? 136.308 147.843 126.465 1.00 73.80  ? 255 VAL   A O   1 
ATOM   1864 C CB  . VAL   A 1 230 ? 134.015 146.919 124.209 1.00 69.29  ? 255 VAL   A CB  1 
ATOM   1865 C CG1 . VAL   A 1 230 ? 134.642 145.633 124.724 1.00 72.81  ? 255 VAL   A CG1 1 
ATOM   1866 C CG2 . VAL   A 1 230 ? 132.513 146.740 123.991 1.00 75.52  ? 255 VAL   A CG2 1 
ATOM   1867 N N   . HIS   A 1 231 ? 136.477 148.891 124.486 1.00 64.84  ? 256 HIS   A N   1 
ATOM   1868 C CA  . HIS   A 1 231 ? 137.936 148.951 124.529 1.00 63.96  ? 256 HIS   A CA  1 
ATOM   1869 C C   . HIS   A 1 231 ? 138.454 150.210 125.219 1.00 66.34  ? 256 HIS   A C   1 
ATOM   1870 O O   . HIS   A 1 231 ? 139.161 150.124 126.228 1.00 69.14  ? 256 HIS   A O   1 
ATOM   1871 C CB  . HIS   A 1 231 ? 138.493 148.870 123.107 1.00 65.44  ? 256 HIS   A CB  1 
ATOM   1872 C CG  . HIS   A 1 231 ? 138.352 147.520 122.481 1.00 68.52  ? 256 HIS   A CG  1 
ATOM   1873 N ND1 . HIS   A 1 231 ? 137.130 146.961 122.181 1.00 73.81  ? 256 HIS   A ND1 1 
ATOM   1874 C CD2 . HIS   A 1 231 ? 139.284 146.616 122.100 1.00 70.65  ? 256 HIS   A CD2 1 
ATOM   1875 C CE1 . HIS   A 1 231 ? 137.316 145.771 121.638 1.00 77.44  ? 256 HIS   A CE1 1 
ATOM   1876 N NE2 . HIS   A 1 231 ? 138.613 145.541 121.574 1.00 75.24  ? 256 HIS   A NE2 1 
ATOM   1877 N N   . TRP   A 1 232 ? 138.112 151.385 124.686 1.00 64.27  ? 257 TRP   A N   1 
ATOM   1878 C CA  . TRP   A 1 232 ? 138.607 152.629 125.267 1.00 65.04  ? 257 TRP   A CA  1 
ATOM   1879 C C   . TRP   A 1 232 ? 138.026 152.860 126.654 1.00 69.19  ? 257 TRP   A C   1 
ATOM   1880 O O   . TRP   A 1 232 ? 138.714 153.373 127.549 1.00 74.63  ? 257 TRP   A O   1 
ATOM   1881 C CB  . TRP   A 1 232 ? 138.275 153.805 124.349 1.00 66.02  ? 257 TRP   A CB  1 
ATOM   1882 C CG  . TRP   A 1 232 ? 139.064 153.852 123.072 1.00 70.78  ? 257 TRP   A CG  1 
ATOM   1883 C CD1 . TRP   A 1 232 ? 140.031 152.981 122.666 1.00 73.41  ? 257 TRP   A CD1 1 
ATOM   1884 C CD2 . TRP   A 1 232 ? 138.951 154.833 122.036 1.00 83.26  ? 257 TRP   A CD2 1 
ATOM   1885 N NE1 . TRP   A 1 232 ? 140.527 153.357 121.444 1.00 75.80  ? 257 TRP   A NE1 1 
ATOM   1886 C CE2 . TRP   A 1 232 ? 139.880 154.493 121.035 1.00 82.51  ? 257 TRP   A CE2 1 
ATOM   1887 C CE3 . TRP   A 1 232 ? 138.154 155.968 121.858 1.00 88.32  ? 257 TRP   A CE3 1 
ATOM   1888 C CZ2 . TRP   A 1 232 ? 140.031 155.241 119.873 1.00 84.85  ? 257 TRP   A CZ2 1 
ATOM   1889 C CZ3 . TRP   A 1 232 ? 138.308 156.711 120.703 1.00 90.01  ? 257 TRP   A CZ3 1 
ATOM   1890 C CH2 . TRP   A 1 232 ? 139.238 156.345 119.726 1.00 86.18  ? 257 TRP   A CH2 1 
ATOM   1891 N N   . GLY   A 1 233 ? 136.758 152.495 126.846 1.00 65.42  ? 258 GLY   A N   1 
ATOM   1892 C CA  . GLY   A 1 233 ? 136.148 152.638 128.154 1.00 67.28  ? 258 GLY   A CA  1 
ATOM   1893 C C   . GLY   A 1 233 ? 136.875 151.846 129.222 1.00 66.53  ? 258 GLY   A C   1 
ATOM   1894 O O   . GLY   A 1 233 ? 137.049 152.320 130.344 1.00 72.35  ? 258 GLY   A O   1 
ATOM   1895 N N   . GLY   A 1 234 ? 137.326 150.638 128.882 1.00 62.04  ? 259 GLY   A N   1 
ATOM   1896 C CA  . GLY   A 1 234 ? 138.062 149.838 129.848 1.00 63.98  ? 259 GLY   A CA  1 
ATOM   1897 C C   . GLY   A 1 234 ? 139.366 150.488 130.267 1.00 64.99  ? 259 GLY   A C   1 
ATOM   1898 O O   . GLY   A 1 234 ? 139.695 150.539 131.453 1.00 74.02  ? 259 GLY   A O   1 
ATOM   1899 N N   . LEU   A 1 235 ? 140.121 151.004 129.297 1.00 58.31  ? 260 LEU   A N   1 
ATOM   1900 C CA  . LEU   A 1 235 ? 141.391 151.657 129.599 1.00 60.15  ? 260 LEU   A CA  1 
ATOM   1901 C C   . LEU   A 1 235 ? 141.179 152.892 130.469 1.00 66.48  ? 260 LEU   A C   1 
ATOM   1902 O O   . LEU   A 1 235 ? 141.855 153.077 131.499 1.00 72.13  ? 260 LEU   A O   1 
ATOM   1903 C CB  . LEU   A 1 235 ? 142.084 152.022 128.287 1.00 57.51  ? 260 LEU   A CB  1 
ATOM   1904 C CG  . LEU   A 1 235 ? 143.375 152.833 128.300 1.00 63.82  ? 260 LEU   A CG  1 
ATOM   1905 C CD1 . LEU   A 1 235 ? 144.476 152.082 129.015 1.00 68.15  ? 260 LEU   A CD1 1 
ATOM   1906 C CD2 . LEU   A 1 235 ? 143.787 153.163 126.876 1.00 62.62  ? 260 LEU   A CD2 1 
ATOM   1907 N N   . LEU   A 1 236 ? 140.236 153.749 130.067 1.00 64.82  ? 261 LEU   A N   1 
ATOM   1908 C CA  . LEU   A 1 236 ? 139.972 154.959 130.834 1.00 62.14  ? 261 LEU   A CA  1 
ATOM   1909 C C   . LEU   A 1 236 ? 139.482 154.621 132.230 1.00 63.48  ? 261 LEU   A C   1 
ATOM   1910 O O   . LEU   A 1 236 ? 139.888 155.261 133.205 1.00 73.68  ? 261 LEU   A O   1 
ATOM   1911 C CB  . LEU   A 1 236 ? 138.954 155.840 130.112 1.00 66.82  ? 261 LEU   A CB  1 
ATOM   1912 C CG  . LEU   A 1 236 ? 139.427 156.562 128.849 1.00 74.04  ? 261 LEU   A CG  1 
ATOM   1913 C CD1 . LEU   A 1 236 ? 138.250 157.230 128.153 1.00 72.86  ? 261 LEU   A CD1 1 
ATOM   1914 C CD2 . LEU   A 1 236 ? 140.503 157.587 129.166 1.00 71.65  ? 261 LEU   A CD2 1 
ATOM   1915 N N   . LEU   A 1 237 ? 138.619 153.613 132.354 1.00 61.22  ? 262 LEU   A N   1 
ATOM   1916 C CA  . LEU   A 1 237 ? 138.115 153.248 133.668 1.00 62.49  ? 262 LEU   A CA  1 
ATOM   1917 C C   . LEU   A 1 237 ? 139.218 152.677 134.538 1.00 67.82  ? 262 LEU   A C   1 
ATOM   1918 O O   . LEU   A 1 237 ? 139.258 152.953 135.736 1.00 71.53  ? 262 LEU   A O   1 
ATOM   1919 C CB  . LEU   A 1 237 ? 136.969 152.252 133.544 1.00 67.73  ? 262 LEU   A CB  1 
ATOM   1920 C CG  . LEU   A 1 237 ? 136.252 151.988 134.871 1.00 71.18  ? 262 LEU   A CG  1 
ATOM   1921 C CD1 . LEU   A 1 237 ? 134.753 151.916 134.638 1.00 75.00  ? 262 LEU   A CD1 1 
ATOM   1922 C CD2 . LEU   A 1 237 ? 136.755 150.723 135.570 1.00 70.89  ? 262 LEU   A CD2 1 
ATOM   1923 N N   . ASP   A 1 238 ? 140.133 151.896 133.960 1.00 67.60  ? 263 ASP   A N   1 
ATOM   1924 C CA  . ASP   A 1 238 ? 141.234 151.358 134.750 1.00 67.13  ? 263 ASP   A CA  1 
ATOM   1925 C C   . ASP   A 1 238 ? 142.079 152.481 135.336 1.00 68.50  ? 263 ASP   A C   1 
ATOM   1926 O O   . ASP   A 1 238 ? 142.271 152.559 136.558 1.00 76.09  ? 263 ASP   A O   1 
ATOM   1927 C CB  . ASP   A 1 238 ? 142.094 150.434 133.891 1.00 63.62  ? 263 ASP   A CB  1 
ATOM   1928 C CG  . ASP   A 1 238 ? 141.375 149.159 133.508 1.00 72.03  ? 263 ASP   A CG  1 
ATOM   1929 O OD1 . ASP   A 1 238 ? 140.202 148.998 133.902 1.00 75.63  ? 263 ASP   A OD1 1 
ATOM   1930 O OD2 . ASP   A 1 238 ? 141.978 148.318 132.812 1.00 74.28  ? 263 ASP   A OD2 1 
ATOM   1931 N N   . LEU   A 1 239 ? 142.541 153.399 134.484 1.00 59.53  ? 264 LEU   A N   1 
ATOM   1932 C CA  . LEU   A 1 239 ? 143.396 154.474 134.988 1.00 63.83  ? 264 LEU   A CA  1 
ATOM   1933 C C   . LEU   A 1 239 ? 142.639 155.392 135.951 1.00 69.17  ? 264 LEU   A C   1 
ATOM   1934 O O   . LEU   A 1 239 ? 143.136 155.714 137.045 1.00 68.40  ? 264 LEU   A O   1 
ATOM   1935 C CB  . LEU   A 1 239 ? 143.972 155.266 133.816 1.00 65.90  ? 264 LEU   A CB  1 
ATOM   1936 C CG  . LEU   A 1 239 ? 144.732 154.446 132.767 1.00 64.28  ? 264 LEU   A CG  1 
ATOM   1937 C CD1 . LEU   A 1 239 ? 145.158 155.326 131.611 1.00 60.99  ? 264 LEU   A CD1 1 
ATOM   1938 C CD2 . LEU   A 1 239 ? 145.941 153.761 133.372 1.00 65.89  ? 264 LEU   A CD2 1 
ATOM   1939 N N   . SER   A 1 240 ? 141.420 155.793 135.586 1.00 66.53  ? 265 SER   A N   1 
ATOM   1940 C CA  . SER   A 1 240 ? 140.673 156.721 136.423 1.00 65.30  ? 265 SER   A CA  1 
ATOM   1941 C C   . SER   A 1 240 ? 140.284 156.081 137.750 1.00 68.05  ? 265 SER   A C   1 
ATOM   1942 O O   . SER   A 1 240 ? 140.412 156.713 138.801 1.00 73.40  ? 265 SER   A O   1 
ATOM   1943 C CB  . SER   A 1 240 ? 139.435 157.214 135.674 1.00 71.56  ? 265 SER   A CB  1 
ATOM   1944 O OG  . SER   A 1 240 ? 138.496 156.169 135.501 1.00 74.73  ? 265 SER   A OG  1 
ATOM   1945 N N   . ALA   A 1 241 ? 139.837 154.823 137.737 1.00 66.68  ? 266 ALA   A N   1 
ATOM   1946 C CA  . ALA   A 1 241 ? 139.525 154.136 138.980 1.00 67.54  ? 266 ALA   A CA  1 
ATOM   1947 C C   . ALA   A 1 241 ? 140.769 153.954 139.827 1.00 64.12  ? 266 ALA   A C   1 
ATOM   1948 O O   . ALA   A 1 241 ? 140.673 153.859 141.054 1.00 61.14  ? 266 ALA   A O   1 
ATOM   1949 C CB  . ALA   A 1 241 ? 138.883 152.783 138.685 1.00 69.45  ? 266 ALA   A CB  1 
ATOM   1950 N N   . GLY   A 1 242 ? 141.941 153.898 139.195 1.00 68.60  ? 267 GLY   A N   1 
ATOM   1951 C CA  . GLY   A 1 242 ? 143.163 154.038 139.962 1.00 73.98  ? 267 GLY   A CA  1 
ATOM   1952 C C   . GLY   A 1 242 ? 143.209 155.360 140.703 1.00 70.59  ? 267 GLY   A C   1 
ATOM   1953 O O   . GLY   A 1 242 ? 143.470 155.400 141.907 1.00 62.79  ? 267 GLY   A O   1 
ATOM   1954 N N   . PHE   A 1 243 ? 142.900 156.457 140.005 1.00 72.01  ? 268 PHE   A N   1 
ATOM   1955 C CA  . PHE   A 1 243 ? 143.099 157.783 140.597 1.00 65.36  ? 268 PHE   A CA  1 
ATOM   1956 C C   . PHE   A 1 243 ? 141.868 158.349 141.308 1.00 62.35  ? 268 PHE   A C   1 
ATOM   1957 O O   . PHE   A 1 243 ? 142.014 159.022 142.332 1.00 65.49  ? 268 PHE   A O   1 
ATOM   1958 C CB  . PHE   A 1 243 ? 143.565 158.762 139.520 1.00 67.01  ? 268 PHE   A CB  1 
ATOM   1959 C CG  . PHE   A 1 243 ? 145.020 158.631 139.180 1.00 71.92  ? 268 PHE   A CG  1 
ATOM   1960 C CD1 . PHE   A 1 243 ? 145.970 159.362 139.865 1.00 72.59  ? 268 PHE   A CD1 1 
ATOM   1961 C CD2 . PHE   A 1 243 ? 145.438 157.765 138.187 1.00 77.53  ? 268 PHE   A CD2 1 
ATOM   1962 C CE1 . PHE   A 1 243 ? 147.307 159.240 139.560 1.00 79.25  ? 268 PHE   A CE1 1 
ATOM   1963 C CE2 . PHE   A 1 243 ? 146.775 157.639 137.879 1.00 81.59  ? 268 PHE   A CE2 1 
ATOM   1964 C CZ  . PHE   A 1 243 ? 147.711 158.377 138.567 1.00 82.26  ? 268 PHE   A CZ  1 
ATOM   1965 N N   . LEU   A 1 244 ? 140.662 158.102 140.792 1.00 66.85  ? 269 LEU   A N   1 
ATOM   1966 C CA  . LEU   A 1 244 ? 139.478 158.823 141.259 1.00 65.85  ? 269 LEU   A CA  1 
ATOM   1967 C C   . LEU   A 1 244 ? 139.148 158.507 142.713 1.00 69.91  ? 269 LEU   A C   1 
ATOM   1968 O O   . LEU   A 1 244 ? 138.805 159.409 143.486 1.00 72.68  ? 269 LEU   A O   1 
ATOM   1969 C CB  . LEU   A 1 244 ? 138.274 158.491 140.376 1.00 63.66  ? 269 LEU   A CB  1 
ATOM   1970 C CG  . LEU   A 1 244 ? 138.251 158.980 138.925 1.00 65.91  ? 269 LEU   A CG  1 
ATOM   1971 C CD1 . LEU   A 1 244 ? 137.117 158.300 138.189 1.00 63.17  ? 269 LEU   A CD1 1 
ATOM   1972 C CD2 . LEU   A 1 244 ? 138.112 160.492 138.814 1.00 69.32  ? 269 LEU   A CD2 1 
ATOM   1973 N N   . LEU   A 1 245 ? 139.230 157.233 143.101 1.00 66.13  ? 270 LEU   A N   1 
ATOM   1974 C CA  . LEU   A 1 245 ? 138.743 156.826 144.416 1.00 61.21  ? 270 LEU   A CA  1 
ATOM   1975 C C   . LEU   A 1 245 ? 139.543 157.456 145.548 1.00 65.59  ? 270 LEU   A C   1 
ATOM   1976 O O   . LEU   A 1 245 ? 139.019 157.625 146.655 1.00 69.81  ? 270 LEU   A O   1 
ATOM   1977 C CB  . LEU   A 1 245 ? 138.776 155.303 144.541 1.00 57.16  ? 270 LEU   A CB  1 
ATOM   1978 C CG  . LEU   A 1 245 ? 137.869 154.506 143.603 1.00 61.90  ? 270 LEU   A CG  1 
ATOM   1979 C CD1 . LEU   A 1 245 ? 138.147 153.027 143.736 1.00 61.22  ? 270 LEU   A CD1 1 
ATOM   1980 C CD2 . LEU   A 1 245 ? 136.405 154.792 143.884 1.00 67.53  ? 270 LEU   A CD2 1 
ATOM   1981 N N   . PHE   A 1 246 ? 140.806 157.803 145.303 1.00 63.67  ? 271 PHE   A N   1 
ATOM   1982 C CA  . PHE   A 1 246 ? 141.655 158.310 146.377 1.00 62.34  ? 271 PHE   A CA  1 
ATOM   1983 C C   . PHE   A 1 246 ? 141.175 159.667 146.876 1.00 65.21  ? 271 PHE   A C   1 
ATOM   1984 O O   . PHE   A 1 246 ? 141.103 159.901 148.088 1.00 71.22  ? 271 PHE   A O   1 
ATOM   1985 C CB  . PHE   A 1 246 ? 143.101 158.393 145.895 1.00 67.05  ? 271 PHE   A CB  1 
ATOM   1986 C CG  . PHE   A 1 246 ? 144.077 158.771 146.966 1.00 70.57  ? 271 PHE   A CG  1 
ATOM   1987 C CD1 . PHE   A 1 246 ? 144.312 157.929 148.035 1.00 73.37  ? 271 PHE   A CD1 1 
ATOM   1988 C CD2 . PHE   A 1 246 ? 144.776 159.959 146.893 1.00 75.35  ? 271 PHE   A CD2 1 
ATOM   1989 C CE1 . PHE   A 1 246 ? 145.214 158.273 149.018 1.00 77.32  ? 271 PHE   A CE1 1 
ATOM   1990 C CE2 . PHE   A 1 246 ? 145.681 160.307 147.872 1.00 76.64  ? 271 PHE   A CE2 1 
ATOM   1991 C CZ  . PHE   A 1 246 ? 145.900 159.464 148.935 1.00 74.92  ? 271 PHE   A CZ  1 
ATOM   1992 N N   . PHE   A 1 247 ? 140.841 160.571 145.962 1.00 64.23  ? 272 PHE   A N   1 
ATOM   1993 C CA  . PHE   A 1 247 ? 140.458 161.924 146.335 1.00 67.58  ? 272 PHE   A CA  1 
ATOM   1994 C C   . PHE   A 1 247 ? 138.986 161.997 146.722 1.00 72.45  ? 272 PHE   A C   1 
ATOM   1995 O O   . PHE   A 1 247 ? 138.141 161.271 146.191 1.00 71.69  ? 272 PHE   A O   1 
ATOM   1996 C CB  . PHE   A 1 247 ? 140.745 162.889 145.189 1.00 68.33  ? 272 PHE   A CB  1 
ATOM   1997 C CG  . PHE   A 1 247 ? 142.190 162.953 144.809 1.00 68.02  ? 272 PHE   A CG  1 
ATOM   1998 C CD1 . PHE   A 1 247 ? 143.071 163.732 145.532 1.00 71.97  ? 272 PHE   A CD1 1 
ATOM   1999 C CD2 . PHE   A 1 247 ? 142.668 162.237 143.732 1.00 68.67  ? 272 PHE   A CD2 1 
ATOM   2000 C CE1 . PHE   A 1 247 ? 144.399 163.794 145.187 1.00 74.05  ? 272 PHE   A CE1 1 
ATOM   2001 C CE2 . PHE   A 1 247 ? 143.996 162.296 143.383 1.00 70.99  ? 272 PHE   A CE2 1 
ATOM   2002 C CZ  . PHE   A 1 247 ? 144.863 163.074 144.111 1.00 74.99  ? 272 PHE   A CZ  1 
ATOM   2003 N N   . ASP   A 1 248 ? 138.686 162.896 147.662 1.00 70.86  ? 273 ASP   A N   1 
ATOM   2004 C CA  . ASP   A 1 248 ? 137.329 163.010 148.184 1.00 66.45  ? 273 ASP   A CA  1 
ATOM   2005 C C   . ASP   A 1 248 ? 136.353 163.516 147.133 1.00 64.80  ? 273 ASP   A C   1 
ATOM   2006 O O   . ASP   A 1 248 ? 135.177 163.138 147.151 1.00 68.60  ? 273 ASP   A O   1 
ATOM   2007 C CB  . ASP   A 1 248 ? 137.312 163.943 149.393 1.00 72.55  ? 273 ASP   A CB  1 
ATOM   2008 C CG  . ASP   A 1 248 ? 138.141 163.417 150.546 1.00 82.04  ? 273 ASP   A CG  1 
ATOM   2009 O OD1 . ASP   A 1 248 ? 138.118 162.193 150.786 1.00 81.97  ? 273 ASP   A OD1 1 
ATOM   2010 O OD2 . ASP   A 1 248 ? 138.818 164.229 151.211 1.00 85.61  ? 273 ASP   A OD2 1 
ATOM   2011 N N   . VAL   A 1 249 ? 136.813 164.375 146.224 1.00 65.50  ? 274 VAL   A N   1 
ATOM   2012 C CA  . VAL   A 1 249 ? 135.911 164.985 145.252 1.00 65.50  ? 274 VAL   A CA  1 
ATOM   2013 C C   . VAL   A 1 249 ? 135.345 163.928 144.311 1.00 69.20  ? 274 VAL   A C   1 
ATOM   2014 O O   . VAL   A 1 249 ? 134.155 163.948 143.976 1.00 69.22  ? 274 VAL   A O   1 
ATOM   2015 C CB  . VAL   A 1 249 ? 136.639 166.100 144.476 1.00 65.25  ? 274 VAL   A CB  1 
ATOM   2016 C CG1 . VAL   A 1 249 ? 135.667 166.834 143.551 1.00 70.14  ? 274 VAL   A CG1 1 
ATOM   2017 C CG2 . VAL   A 1 249 ? 137.311 167.074 145.437 1.00 64.72  ? 274 VAL   A CG2 1 
ATOM   2018 N N   . SER   A 1 250 ? 136.182 162.987 143.880 1.00 66.52  ? 275 SER   A N   1 
ATOM   2019 C CA  . SER   A 1 250 ? 135.852 162.066 142.803 1.00 65.43  ? 275 SER   A CA  1 
ATOM   2020 C C   . SER   A 1 250 ? 135.404 160.690 143.285 1.00 67.14  ? 275 SER   A C   1 
ATOM   2021 O O   . SER   A 1 250 ? 135.258 159.782 142.461 1.00 75.00  ? 275 SER   A O   1 
ATOM   2022 C CB  . SER   A 1 250 ? 137.058 161.910 141.879 1.00 74.75  ? 275 SER   A CB  1 
ATOM   2023 O OG  . SER   A 1 250 ? 137.420 163.151 141.299 1.00 79.76  ? 275 SER   A OG  1 
ATOM   2024 N N   . ARG   A 1 251 ? 135.177 160.505 144.586 1.00 65.18  ? 276 ARG   A N   1 
ATOM   2025 C CA  . ARG   A 1 251 ? 134.954 159.151 145.086 1.00 65.79  ? 276 ARG   A CA  1 
ATOM   2026 C C   . ARG   A 1 251 ? 133.584 158.615 144.685 1.00 65.67  ? 276 ARG   A C   1 
ATOM   2027 O O   . ARG   A 1 251 ? 133.445 157.420 144.409 1.00 71.53  ? 276 ARG   A O   1 
ATOM   2028 C CB  . ARG   A 1 251 ? 135.124 159.098 146.603 1.00 67.11  ? 276 ARG   A CB  1 
ATOM   2029 C CG  . ARG   A 1 251 ? 135.279 157.675 147.119 1.00 63.93  ? 276 ARG   A CG  1 
ATOM   2030 C CD  . ARG   A 1 251 ? 135.554 157.597 148.610 1.00 64.53  ? 276 ARG   A CD  1 
ATOM   2031 N NE  . ARG   A 1 251 ? 136.836 158.190 148.979 1.00 62.22  ? 276 ARG   A NE  1 
ATOM   2032 C CZ  . ARG   A 1 251 ? 137.014 159.370 149.563 1.00 67.64  ? 276 ARG   A CZ  1 
ATOM   2033 N NH1 . ARG   A 1 251 ? 136.000 160.165 149.871 1.00 71.84  ? 276 ARG   A NH1 1 
ATOM   2034 N NH2 . ARG   A 1 251 ? 138.250 159.766 149.851 1.00 70.48  ? 276 ARG   A NH2 1 
ATOM   2035 N N   . SER   A 1 252 ? 132.557 159.467 144.655 1.00 57.19  ? 277 SER   A N   1 
ATOM   2036 C CA  . SER   A 1 252 ? 131.214 158.980 144.343 1.00 64.50  ? 277 SER   A CA  1 
ATOM   2037 C C   . SER   A 1 252 ? 131.119 158.491 142.901 1.00 69.59  ? 277 SER   A C   1 
ATOM   2038 O O   . SER   A 1 252 ? 130.642 157.376 142.638 1.00 72.17  ? 277 SER   A O   1 
ATOM   2039 C CB  . SER   A 1 252 ? 130.189 160.080 144.603 1.00 66.05  ? 277 SER   A CB  1 
ATOM   2040 O OG  . SER   A 1 252 ? 130.434 161.208 143.782 1.00 73.44  ? 277 SER   A OG  1 
ATOM   2041 N N   . ILE   A 1 253 ? 131.564 159.317 141.953 1.00 66.13  ? 278 ILE   A N   1 
ATOM   2042 C CA  . ILE   A 1 253 ? 131.520 158.934 140.545 1.00 66.69  ? 278 ILE   A CA  1 
ATOM   2043 C C   . ILE   A 1 253 ? 132.401 157.719 140.306 1.00 69.40  ? 278 ILE   A C   1 
ATOM   2044 O O   . ILE   A 1 253 ? 132.051 156.813 139.533 1.00 75.15  ? 278 ILE   A O   1 
ATOM   2045 C CB  . ILE   A 1 253 ? 131.943 160.120 139.655 1.00 71.19  ? 278 ILE   A CB  1 
ATOM   2046 C CG1 . ILE   A 1 253 ? 131.040 161.345 139.881 1.00 74.26  ? 278 ILE   A CG1 1 
ATOM   2047 C CG2 . ILE   A 1 253 ? 131.952 159.707 138.186 1.00 75.72  ? 278 ILE   A CG2 1 
ATOM   2048 C CD1 . ILE   A 1 253 ? 129.555 161.129 139.596 1.00 76.55  ? 278 ILE   A CD1 1 
ATOM   2049 N N   . GLY   A 1 254 ? 133.570 157.693 140.946 1.00 65.36  ? 279 GLY   A N   1 
ATOM   2050 C CA  . GLY   A 1 254 ? 134.442 156.539 140.830 1.00 66.18  ? 279 GLY   A CA  1 
ATOM   2051 C C   . GLY   A 1 254 ? 133.784 155.266 141.319 1.00 64.87  ? 279 GLY   A C   1 
ATOM   2052 O O   . GLY   A 1 254 ? 133.874 154.226 140.666 1.00 72.11  ? 279 GLY   A O   1 
ATOM   2053 N N   . LEU   A 1 255 ? 133.114 155.329 142.472 1.00 59.52  ? 280 LEU   A N   1 
ATOM   2054 C CA  . LEU   A 1 255 ? 132.430 154.150 142.988 1.00 60.43  ? 280 LEU   A CA  1 
ATOM   2055 C C   . LEU   A 1 255 ? 131.344 153.687 142.032 1.00 63.21  ? 280 LEU   A C   1 
ATOM   2056 O O   . LEU   A 1 255 ? 131.209 152.485 141.774 1.00 69.35  ? 280 LEU   A O   1 
ATOM   2057 C CB  . LEU   A 1 255 ? 131.835 154.435 144.367 1.00 58.25  ? 280 LEU   A CB  1 
ATOM   2058 C CG  . LEU   A 1 255 ? 132.767 154.440 145.582 1.00 61.50  ? 280 LEU   A CG  1 
ATOM   2059 C CD1 . LEU   A 1 255 ? 131.987 154.830 146.821 1.00 62.51  ? 280 LEU   A CD1 1 
ATOM   2060 C CD2 . LEU   A 1 255 ? 133.436 153.092 145.791 1.00 62.75  ? 280 LEU   A CD2 1 
ATOM   2061 N N   . PHE   A 1 256 ? 130.569 154.625 141.483 1.00 62.90  ? 281 PHE   A N   1 
ATOM   2062 C CA  . PHE   A 1 256 ? 129.504 154.246 140.557 1.00 62.82  ? 281 PHE   A CA  1 
ATOM   2063 C C   . PHE   A 1 256 ? 130.066 153.542 139.325 1.00 66.08  ? 281 PHE   A C   1 
ATOM   2064 O O   . PHE   A 1 256 ? 129.626 152.438 138.968 1.00 71.23  ? 281 PHE   A O   1 
ATOM   2065 C CB  . PHE   A 1 256 ? 128.704 155.481 140.149 1.00 63.93  ? 281 PHE   A CB  1 
ATOM   2066 C CG  . PHE   A 1 256 ? 127.534 155.178 139.261 1.00 69.64  ? 281 PHE   A CG  1 
ATOM   2067 C CD1 . PHE   A 1 256 ? 126.321 154.793 139.802 1.00 77.32  ? 281 PHE   A CD1 1 
ATOM   2068 C CD2 . PHE   A 1 256 ? 127.642 155.287 137.887 1.00 71.76  ? 281 PHE   A CD2 1 
ATOM   2069 C CE1 . PHE   A 1 256 ? 125.242 154.515 138.988 1.00 83.47  ? 281 PHE   A CE1 1 
ATOM   2070 C CE2 . PHE   A 1 256 ? 126.569 155.010 137.069 1.00 75.41  ? 281 PHE   A CE2 1 
ATOM   2071 C CZ  . PHE   A 1 256 ? 125.367 154.625 137.619 1.00 82.55  ? 281 PHE   A CZ  1 
ATOM   2072 N N   . PHE   A 1 257 ? 131.044 154.168 138.663 1.00 62.01  ? 282 PHE   A N   1 
ATOM   2073 C CA  . PHE   A 1 257 ? 131.604 153.575 137.452 1.00 60.55  ? 282 PHE   A CA  1 
ATOM   2074 C C   . PHE   A 1 257 ? 132.284 152.246 137.745 1.00 67.23  ? 282 PHE   A C   1 
ATOM   2075 O O   . PHE   A 1 257 ? 132.141 151.289 136.976 1.00 73.78  ? 282 PHE   A O   1 
ATOM   2076 C CB  . PHE   A 1 257 ? 132.598 154.537 136.790 1.00 62.77  ? 282 PHE   A CB  1 
ATOM   2077 C CG  . PHE   A 1 257 ? 131.975 155.774 136.159 1.00 65.94  ? 282 PHE   A CG  1 
ATOM   2078 C CD1 . PHE   A 1 257 ? 130.609 155.899 135.952 1.00 65.62  ? 282 PHE   A CD1 1 
ATOM   2079 C CD2 . PHE   A 1 257 ? 132.790 156.815 135.756 1.00 72.54  ? 282 PHE   A CD2 1 
ATOM   2080 C CE1 . PHE   A 1 257 ? 130.080 157.032 135.373 1.00 68.37  ? 282 PHE   A CE1 1 
ATOM   2081 C CE2 . PHE   A 1 257 ? 132.263 157.949 135.176 1.00 75.20  ? 282 PHE   A CE2 1 
ATOM   2082 C CZ  . PHE   A 1 257 ? 130.906 158.056 134.985 1.00 73.76  ? 282 PHE   A CZ  1 
ATOM   2083 N N   . VAL   A 1 258 ? 133.028 152.160 138.849 1.00 61.03  ? 283 VAL   A N   1 
ATOM   2084 C CA  . VAL   A 1 258 ? 133.737 150.927 139.169 1.00 58.36  ? 283 VAL   A CA  1 
ATOM   2085 C C   . VAL   A 1 258 ? 132.754 149.802 139.466 1.00 63.81  ? 283 VAL   A C   1 
ATOM   2086 O O   . VAL   A 1 258 ? 132.961 148.656 139.048 1.00 70.70  ? 283 VAL   A O   1 
ATOM   2087 C CB  . VAL   A 1 258 ? 134.709 151.170 140.336 1.00 57.98  ? 283 VAL   A CB  1 
ATOM   2088 C CG1 . VAL   A 1 258 ? 135.249 149.864 140.873 1.00 63.76  ? 283 VAL   A CG1 1 
ATOM   2089 C CG2 . VAL   A 1 258 ? 135.860 152.044 139.882 1.00 62.52  ? 283 VAL   A CG2 1 
ATOM   2090 N N   . SER   A 1 259 ? 131.675 150.099 140.195 1.00 61.90  ? 284 SER   A N   1 
ATOM   2091 C CA  . SER   A 1 259 ? 130.687 149.069 140.489 1.00 63.09  ? 284 SER   A CA  1 
ATOM   2092 C C   . SER   A 1 259 ? 129.999 148.587 139.220 1.00 65.55  ? 284 SER   A C   1 
ATOM   2093 O O   . SER   A 1 259 ? 129.782 147.381 139.043 1.00 72.65  ? 284 SER   A O   1 
ATOM   2094 C CB  . SER   A 1 259 ? 129.661 149.600 141.487 1.00 67.35  ? 284 SER   A CB  1 
ATOM   2095 O OG  . SER   A 1 259 ? 130.273 149.913 142.724 1.00 75.07  ? 284 SER   A OG  1 
ATOM   2096 N N   . TYR   A 1 260 ? 129.637 149.514 138.328 1.00 61.78  ? 285 TYR   A N   1 
ATOM   2097 C CA  . TYR   A 1 260 ? 129.028 149.109 137.064 1.00 62.62  ? 285 TYR   A CA  1 
ATOM   2098 C C   . TYR   A 1 260 ? 129.985 148.249 136.248 1.00 63.79  ? 285 TYR   A C   1 
ATOM   2099 O O   . TYR   A 1 260 ? 129.587 147.225 135.675 1.00 70.44  ? 285 TYR   A O   1 
ATOM   2100 C CB  . TYR   A 1 260 ? 128.601 150.351 136.283 1.00 65.47  ? 285 TYR   A CB  1 
ATOM   2101 C CG  . TYR   A 1 260 ? 127.805 150.076 135.031 1.00 65.97  ? 285 TYR   A CG  1 
ATOM   2102 C CD1 . TYR   A 1 260 ? 126.588 149.414 135.088 1.00 73.93  ? 285 TYR   A CD1 1 
ATOM   2103 C CD2 . TYR   A 1 260 ? 128.258 150.505 133.797 1.00 69.36  ? 285 TYR   A CD2 1 
ATOM   2104 C CE1 . TYR   A 1 260 ? 125.857 149.169 133.945 1.00 82.45  ? 285 TYR   A CE1 1 
ATOM   2105 C CE2 . TYR   A 1 260 ? 127.535 150.266 132.650 1.00 76.91  ? 285 TYR   A CE2 1 
ATOM   2106 C CZ  . TYR   A 1 260 ? 126.335 149.599 132.728 1.00 82.92  ? 285 TYR   A CZ  1 
ATOM   2107 O OH  . TYR   A 1 260 ? 125.609 149.361 131.583 1.00 83.55  ? 285 TYR   A OH  1 
ATOM   2108 N N   . PHE   A 1 261 ? 131.259 148.644 136.210 1.00 62.17  ? 286 PHE   A N   1 
ATOM   2109 C CA  . PHE   A 1 261 ? 132.286 147.886 135.506 1.00 64.48  ? 286 PHE   A CA  1 
ATOM   2110 C C   . PHE   A 1 261 ? 132.394 146.469 136.051 1.00 65.69  ? 286 PHE   A C   1 
ATOM   2111 O O   . PHE   A 1 261 ? 132.423 145.495 135.289 1.00 69.14  ? 286 PHE   A O   1 
ATOM   2112 C CB  . PHE   A 1 261 ? 133.610 148.639 135.645 1.00 65.34  ? 286 PHE   A CB  1 
ATOM   2113 C CG  . PHE   A 1 261 ? 134.798 147.943 135.057 1.00 62.37  ? 286 PHE   A CG  1 
ATOM   2114 C CD1 . PHE   A 1 261 ? 135.100 148.073 133.720 1.00 71.07  ? 286 PHE   A CD1 1 
ATOM   2115 C CD2 . PHE   A 1 261 ? 135.648 147.209 135.857 1.00 66.60  ? 286 PHE   A CD2 1 
ATOM   2116 C CE1 . PHE   A 1 261 ? 136.206 147.457 133.186 1.00 75.34  ? 286 PHE   A CE1 1 
ATOM   2117 C CE2 . PHE   A 1 261 ? 136.753 146.590 135.328 1.00 70.56  ? 286 PHE   A CE2 1 
ATOM   2118 C CZ  . PHE   A 1 261 ? 137.034 146.716 133.992 1.00 73.20  ? 286 PHE   A CZ  1 
ATOM   2119 N N   . HIS   A 1 262 ? 132.428 146.334 137.376 1.00 63.69  ? 287 HIS   A N   1 
ATOM   2120 C CA  . HIS   A 1 262 ? 132.611 145.020 137.977 1.00 60.82  ? 287 HIS   A CA  1 
ATOM   2121 C C   . HIS   A 1 262 ? 131.381 144.141 137.790 1.00 64.62  ? 287 HIS   A C   1 
ATOM   2122 O O   . HIS   A 1 262 ? 131.511 142.937 137.547 1.00 70.58  ? 287 HIS   A O   1 
ATOM   2123 C CB  . HIS   A 1 262 ? 132.953 145.171 139.457 1.00 63.77  ? 287 HIS   A CB  1 
ATOM   2124 C CG  . HIS   A 1 262 ? 134.319 145.730 139.705 1.00 62.65  ? 287 HIS   A CG  1 
ATOM   2125 N ND1 . HIS   A 1 262 ? 135.395 145.457 138.889 1.00 60.83  ? 287 HIS   A ND1 1 
ATOM   2126 C CD2 . HIS   A 1 262 ? 134.785 146.546 140.678 1.00 63.44  ? 287 HIS   A CD2 1 
ATOM   2127 C CE1 . HIS   A 1 262 ? 136.463 146.081 139.347 1.00 62.21  ? 287 HIS   A CE1 1 
ATOM   2128 N NE2 . HIS   A 1 262 ? 136.120 146.750 140.432 1.00 64.61  ? 287 HIS   A NE2 1 
ATOM   2129 N N   . CYS   A 1 263 ? 130.179 144.712 137.897 1.00 66.20  ? 288 CYS   A N   1 
ATOM   2130 C CA  . CYS   A 1 263 ? 128.973 143.923 137.651 1.00 65.69  ? 288 CYS   A CA  1 
ATOM   2131 C C   . CYS   A 1 263 ? 128.912 143.436 136.207 1.00 64.85  ? 288 CYS   A C   1 
ATOM   2132 O O   . CYS   A 1 263 ? 128.575 142.270 135.945 1.00 68.02  ? 288 CYS   A O   1 
ATOM   2133 C CB  . CYS   A 1 263 ? 127.732 144.745 137.991 1.00 67.77  ? 288 CYS   A CB  1 
ATOM   2134 S SG  . CYS   A 1 263 ? 127.488 145.023 139.757 1.00 85.99  ? 288 CYS   A SG  1 
ATOM   2135 N N   . MET   A 1 264 ? 129.238 144.311 135.252 1.00 61.71  ? 289 MET   A N   1 
ATOM   2136 C CA  . MET   A 1 264 ? 129.228 143.891 133.856 1.00 62.60  ? 289 MET   A CA  1 
ATOM   2137 C C   . MET   A 1 264 ? 130.280 142.822 133.600 1.00 66.15  ? 289 MET   A C   1 
ATOM   2138 O O   . MET   A 1 264 ? 130.036 141.874 132.847 1.00 72.32  ? 289 MET   A O   1 
ATOM   2139 C CB  . MET   A 1 264 ? 129.438 145.089 132.931 1.00 64.15  ? 289 MET   A CB  1 
ATOM   2140 C CG  . MET   A 1 264 ? 128.152 145.624 132.329 1.00 68.43  ? 289 MET   A CG  1 
ATOM   2141 S SD  . MET   A 1 264 ? 128.432 146.931 131.125 1.00 92.01  ? 289 MET   A SD  1 
ATOM   2142 C CE  . MET   A 1 264 ? 126.850 146.957 130.290 1.00 83.10  ? 289 MET   A CE  1 
ATOM   2143 N N   . ASN   A 1 265 ? 131.455 142.949 134.220 1.00 65.96  ? 290 ASN   A N   1 
ATOM   2144 C CA  . ASN   A 1 265 ? 132.470 141.911 134.071 1.00 62.92  ? 290 ASN   A CA  1 
ATOM   2145 C C   . ASN   A 1 265 ? 132.003 140.597 134.678 1.00 62.66  ? 290 ASN   A C   1 
ATOM   2146 O O   . ASN   A 1 265 ? 132.296 139.520 134.146 1.00 67.69  ? 290 ASN   A O   1 
ATOM   2147 C CB  . ASN   A 1 265 ? 133.777 142.361 134.714 1.00 64.45  ? 290 ASN   A CB  1 
ATOM   2148 C CG  . ASN   A 1 265 ? 134.527 143.347 133.862 1.00 70.48  ? 290 ASN   A CG  1 
ATOM   2149 O OD1 . ASN   A 1 265 ? 134.005 143.846 132.866 1.00 72.72  ? 290 ASN   A OD1 1 
ATOM   2150 N ND2 . ASN   A 1 265 ? 135.758 143.639 134.245 1.00 73.65  ? 290 ASN   A ND2 1 
ATOM   2151 N N   . SER   A 1 266 ? 131.283 140.664 135.797 1.00 60.40  ? 291 SER   A N   1 
ATOM   2152 C CA  . SER   A 1 266 ? 130.768 139.450 136.417 1.00 62.64  ? 291 SER   A CA  1 
ATOM   2153 C C   . SER   A 1 266 ? 129.793 138.739 135.496 1.00 63.97  ? 291 SER   A C   1 
ATOM   2154 O O   . SER   A 1 266 ? 129.829 137.510 135.370 1.00 67.11  ? 291 SER   A O   1 
ATOM   2155 C CB  . SER   A 1 266 ? 130.091 139.786 137.743 1.00 67.97  ? 291 SER   A CB  1 
ATOM   2156 O OG  . SER   A 1 266 ? 129.349 138.681 138.226 1.00 72.63  ? 291 SER   A OG  1 
ATOM   2157 N N   . GLN   A 1 267 ? 128.913 139.494 134.840 1.00 68.49  ? 292 GLN   A N   1 
ATOM   2158 C CA  . GLN   A 1 267 ? 127.921 138.855 133.980 1.00 62.83  ? 292 GLN   A CA  1 
ATOM   2159 C C   . GLN   A 1 267 ? 128.524 138.384 132.661 1.00 58.85  ? 292 GLN   A C   1 
ATOM   2160 O O   . GLN   A 1 267 ? 128.135 137.333 132.143 1.00 59.29  ? 292 GLN   A O   1 
ATOM   2161 C CB  . GLN   A 1 267 ? 126.756 139.808 133.715 1.00 66.60  ? 292 GLN   A CB  1 
ATOM   2162 C CG  . GLN   A 1 267 ? 126.006 140.251 134.965 1.00 73.88  ? 292 GLN   A CG  1 
ATOM   2163 C CD  . GLN   A 1 267 ? 125.362 139.096 135.707 1.00 77.51  ? 292 GLN   A CD  1 
ATOM   2164 O OE1 . GLN   A 1 267 ? 125.218 138.001 135.167 1.00 71.00  ? 292 GLN   A OE1 1 
ATOM   2165 N NE2 . GLN   A 1 267 ? 124.975 139.336 136.955 1.00 80.60  ? 292 GLN   A NE2 1 
ATOM   2166 N N   . LEU   A 1 268 ? 129.468 139.139 132.098 1.00 61.05  ? 293 LEU   A N   1 
ATOM   2167 C CA  . LEU   A 1 268 ? 129.967 138.820 130.763 1.00 59.55  ? 293 LEU   A CA  1 
ATOM   2168 C C   . LEU   A 1 268 ? 130.860 137.586 130.771 1.00 62.20  ? 293 LEU   A C   1 
ATOM   2169 O O   . LEU   A 1 268 ? 130.739 136.726 129.891 1.00 67.05  ? 293 LEU   A O   1 
ATOM   2170 C CB  . LEU   A 1 268 ? 130.725 140.015 130.185 1.00 60.91  ? 293 LEU   A CB  1 
ATOM   2171 C CG  . LEU   A 1 268 ? 129.910 141.237 129.763 1.00 67.82  ? 293 LEU   A CG  1 
ATOM   2172 C CD1 . LEU   A 1 268 ? 130.830 142.383 129.402 1.00 65.36  ? 293 LEU   A CD1 1 
ATOM   2173 C CD2 . LEU   A 1 268 ? 128.997 140.910 128.594 1.00 73.99  ? 293 LEU   A CD2 1 
ATOM   2174 N N   . PHE   A 1 269 ? 131.759 137.480 131.744 1.00 61.90  ? 294 PHE   A N   1 
ATOM   2175 C CA  . PHE   A 1 269 ? 132.780 136.442 131.791 1.00 58.32  ? 294 PHE   A CA  1 
ATOM   2176 C C   . PHE   A 1 269 ? 132.447 135.416 132.869 1.00 65.60  ? 294 PHE   A C   1 
ATOM   2177 O O   . PHE   A 1 269 ? 131.464 135.542 133.604 1.00 72.66  ? 294 PHE   A O   1 
ATOM   2178 C CB  . PHE   A 1 269 ? 134.153 137.063 132.040 1.00 58.33  ? 294 PHE   A CB  1 
ATOM   2179 C CG  . PHE   A 1 269 ? 134.583 138.027 130.978 1.00 61.07  ? 294 PHE   A CG  1 
ATOM   2180 C CD1 . PHE   A 1 269 ? 135.295 137.590 129.880 1.00 66.04  ? 294 PHE   A CD1 1 
ATOM   2181 C CD2 . PHE   A 1 269 ? 134.289 139.369 131.084 1.00 65.06  ? 294 PHE   A CD2 1 
ATOM   2182 C CE1 . PHE   A 1 269 ? 135.696 138.473 128.905 1.00 68.42  ? 294 PHE   A CE1 1 
ATOM   2183 C CE2 . PHE   A 1 269 ? 134.686 140.253 130.114 1.00 65.06  ? 294 PHE   A CE2 1 
ATOM   2184 C CZ  . PHE   A 1 269 ? 135.392 139.808 129.024 1.00 67.68  ? 294 PHE   A CZ  1 
ATOM   2185 N N   . SER   A 1 270 ? 133.289 134.387 132.951 1.00 59.28  ? 295 SER   A N   1 
ATOM   2186 C CA  . SER   A 1 270 ? 133.211 133.338 133.959 1.00 61.25  ? 295 SER   A CA  1 
ATOM   2187 C C   . SER   A 1 270 ? 134.453 133.357 134.839 1.00 65.39  ? 295 SER   A C   1 
ATOM   2188 O O   . SER   A 1 270 ? 135.010 132.315 135.185 1.00 67.85  ? 295 SER   A O   1 
ATOM   2189 C CB  . SER   A 1 270 ? 133.040 131.969 133.308 1.00 67.37  ? 295 SER   A CB  1 
ATOM   2190 O OG  . SER   A 1 270 ? 134.158 131.654 132.499 1.00 75.35  ? 295 SER   A OG  1 
ATOM   2191 N N   . ILE   A 1 271 ? 134.898 134.561 135.205 1.00 65.39  ? 296 ILE   A N   1 
ATOM   2192 C CA  . ILE   A 1 271 ? 136.123 134.704 135.986 1.00 63.82  ? 296 ILE   A CA  1 
ATOM   2193 C C   . ILE   A 1 271 ? 135.964 134.072 137.364 1.00 69.73  ? 296 ILE   A C   1 
ATOM   2194 O O   . ILE   A 1 271 ? 136.909 133.479 137.896 1.00 72.12  ? 296 ILE   A O   1 
ATOM   2195 C CB  . ILE   A 1 271 ? 136.527 136.189 136.080 1.00 64.37  ? 296 ILE   A CB  1 
ATOM   2196 C CG1 . ILE   A 1 271 ? 135.459 137.024 136.802 1.00 65.64  ? 296 ILE   A CG1 1 
ATOM   2197 C CG2 . ILE   A 1 271 ? 136.787 136.754 134.693 1.00 66.32  ? 296 ILE   A CG2 1 
ATOM   2198 C CD1 . ILE   A 1 271 ? 135.723 138.514 136.765 1.00 69.02  ? 296 ILE   A CD1 1 
ATOM   2199 N N   . GLY   A 1 272 ? 134.777 134.186 137.959 1.00 68.73  ? 297 GLY   A N   1 
ATOM   2200 C CA  . GLY   A 1 272 ? 134.490 133.596 139.255 1.00 64.51  ? 297 GLY   A CA  1 
ATOM   2201 C C   . GLY   A 1 272 ? 134.158 134.623 140.315 1.00 71.19  ? 297 GLY   A C   1 
ATOM   2202 O O   . GLY   A 1 272 ? 133.186 135.371 140.176 1.00 77.38  ? 297 GLY   A O   1 
ATOM   2203 N N   . MET   A 1 273 ? 134.959 134.670 141.378 1.00 67.52  ? 298 MET   A N   1 
ATOM   2204 C CA  . MET   A 1 273 ? 134.736 135.571 142.501 1.00 66.82  ? 298 MET   A CA  1 
ATOM   2205 C C   . MET   A 1 273 ? 135.562 136.850 142.409 1.00 68.13  ? 298 MET   A C   1 
ATOM   2206 O O   . MET   A 1 273 ? 135.568 137.636 143.361 1.00 74.00  ? 298 MET   A O   1 
ATOM   2207 C CB  . MET   A 1 273 ? 135.047 134.854 143.815 1.00 66.19  ? 298 MET   A CB  1 
ATOM   2208 C CG  . MET   A 1 273 ? 134.175 133.646 144.100 1.00 68.15  ? 298 MET   A CG  1 
ATOM   2209 S SD  . MET   A 1 273 ? 132.454 134.063 144.408 1.00 83.18  ? 298 MET   A SD  1 
ATOM   2210 C CE  . MET   A 1 273 ? 131.789 132.449 144.793 1.00 77.88  ? 298 MET   A CE  1 
ATOM   2211 N N   . PHE   A 1 274 ? 136.257 137.076 141.292 1.00 62.24  ? 299 PHE   A N   1 
ATOM   2212 C CA  . PHE   A 1 274 ? 137.143 138.230 141.178 1.00 59.30  ? 299 PHE   A CA  1 
ATOM   2213 C C   . PHE   A 1 274 ? 136.362 139.534 141.272 1.00 63.40  ? 299 PHE   A C   1 
ATOM   2214 O O   . PHE   A 1 274 ? 136.764 140.466 141.983 1.00 70.93  ? 299 PHE   A O   1 
ATOM   2215 C CB  . PHE   A 1 274 ? 137.904 138.141 139.852 1.00 59.52  ? 299 PHE   A CB  1 
ATOM   2216 C CG  . PHE   A 1 274 ? 138.970 139.196 139.649 1.00 58.59  ? 299 PHE   A CG  1 
ATOM   2217 C CD1 . PHE   A 1 274 ? 139.564 139.867 140.705 1.00 65.46  ? 299 PHE   A CD1 1 
ATOM   2218 C CD2 . PHE   A 1 274 ? 139.390 139.495 138.369 1.00 60.65  ? 299 PHE   A CD2 1 
ATOM   2219 C CE1 . PHE   A 1 274 ? 140.537 140.813 140.480 1.00 68.61  ? 299 PHE   A CE1 1 
ATOM   2220 C CE2 . PHE   A 1 274 ? 140.361 140.437 138.143 1.00 67.12  ? 299 PHE   A CE2 1 
ATOM   2221 C CZ  . PHE   A 1 274 ? 140.936 141.097 139.199 1.00 69.45  ? 299 PHE   A CZ  1 
ATOM   2222 N N   . SER   A 1 275 ? 135.235 139.614 140.565 1.00 60.67  ? 300 SER   A N   1 
ATOM   2223 C CA  . SER   A 1 275 ? 134.451 140.843 140.551 1.00 62.95  ? 300 SER   A CA  1 
ATOM   2224 C C   . SER   A 1 275 ? 133.921 141.173 141.938 1.00 66.92  ? 300 SER   A C   1 
ATOM   2225 O O   . SER   A 1 275 ? 133.924 142.338 142.353 1.00 68.47  ? 300 SER   A O   1 
ATOM   2226 C CB  . SER   A 1 275 ? 133.303 140.714 139.556 1.00 62.65  ? 300 SER   A CB  1 
ATOM   2227 O OG  . SER   A 1 275 ? 132.474 141.861 139.593 1.00 69.56  ? 300 SER   A OG  1 
ATOM   2228 N N   . TYR   A 1 276 ? 133.469 140.159 142.674 1.00 64.77  ? 301 TYR   A N   1 
ATOM   2229 C CA  . TYR   A 1 276 ? 132.924 140.401 144.003 1.00 60.59  ? 301 TYR   A CA  1 
ATOM   2230 C C   . TYR   A 1 276 ? 134.015 140.837 144.973 1.00 62.78  ? 301 TYR   A C   1 
ATOM   2231 O O   . TYR   A 1 276 ? 133.787 141.710 145.819 1.00 69.52  ? 301 TYR   A O   1 
ATOM   2232 C CB  . TYR   A 1 276 ? 132.207 139.149 144.499 1.00 63.68  ? 301 TYR   A CB  1 
ATOM   2233 C CG  . TYR   A 1 276 ? 131.118 138.688 143.558 1.00 71.38  ? 301 TYR   A CG  1 
ATOM   2234 C CD1 . TYR   A 1 276 ? 129.851 139.246 143.605 1.00 73.46  ? 301 TYR   A CD1 1 
ATOM   2235 C CD2 . TYR   A 1 276 ? 131.360 137.703 142.617 1.00 71.36  ? 301 TYR   A CD2 1 
ATOM   2236 C CE1 . TYR   A 1 276 ? 128.861 138.833 142.746 1.00 72.71  ? 301 TYR   A CE1 1 
ATOM   2237 C CE2 . TYR   A 1 276 ? 130.376 137.285 141.755 1.00 70.12  ? 301 TYR   A CE2 1 
ATOM   2238 C CZ  . TYR   A 1 276 ? 129.129 137.853 141.822 1.00 71.94  ? 301 TYR   A CZ  1 
ATOM   2239 O OH  . TYR   A 1 276 ? 128.142 137.434 140.962 1.00 78.83  ? 301 TYR   A OH  1 
ATOM   2240 N N   . VAL   A 1 277 ? 135.208 140.250 144.865 1.00 60.60  ? 302 VAL   A N   1 
ATOM   2241 C CA  . VAL   A 1 277 ? 136.319 140.677 145.712 1.00 59.34  ? 302 VAL   A CA  1 
ATOM   2242 C C   . VAL   A 1 277 ? 136.692 142.120 145.409 1.00 62.07  ? 302 VAL   A C   1 
ATOM   2243 O O   . VAL   A 1 277 ? 136.976 142.905 146.321 1.00 66.36  ? 302 VAL   A O   1 
ATOM   2244 C CB  . VAL   A 1 277 ? 137.522 139.731 145.545 1.00 62.18  ? 302 VAL   A CB  1 
ATOM   2245 C CG1 . VAL   A 1 277 ? 138.752 140.300 146.227 1.00 64.79  ? 302 VAL   A CG1 1 
ATOM   2246 C CG2 . VAL   A 1 277 ? 137.200 138.364 146.115 1.00 65.20  ? 302 VAL   A CG2 1 
ATOM   2247 N N   . MET   A 1 278 ? 136.708 142.497 144.128 1.00 59.10  ? 303 MET   A N   1 
ATOM   2248 C CA  . MET   A 1 278 ? 137.014 143.884 143.789 1.00 61.79  ? 303 MET   A CA  1 
ATOM   2249 C C   . MET   A 1 278 ? 135.938 144.833 144.309 1.00 63.82  ? 303 MET   A C   1 
ATOM   2250 O O   . MET   A 1 278 ? 136.245 145.938 144.777 1.00 65.49  ? 303 MET   A O   1 
ATOM   2251 C CB  . MET   A 1 278 ? 137.175 144.036 142.278 1.00 62.85  ? 303 MET   A CB  1 
ATOM   2252 C CG  . MET   A 1 278 ? 138.418 143.372 141.701 1.00 64.09  ? 303 MET   A CG  1 
ATOM   2253 S SD  . MET   A 1 278 ? 139.987 144.034 142.303 1.00 74.53  ? 303 MET   A SD  1 
ATOM   2254 C CE  . MET   A 1 278 ? 139.860 145.753 141.826 1.00 71.03  ? 303 MET   A CE  1 
ATOM   2255 N N   . LEU   A 1 279 ? 134.669 144.426 144.227 1.00 62.88  ? 304 LEU   A N   1 
ATOM   2256 C CA  . LEU   A 1 279 ? 133.599 145.246 144.785 1.00 60.06  ? 304 LEU   A CA  1 
ATOM   2257 C C   . LEU   A 1 279 ? 133.770 145.421 146.287 1.00 62.46  ? 304 LEU   A C   1 
ATOM   2258 O O   . LEU   A 1 279 ? 133.546 146.511 146.820 1.00 63.88  ? 304 LEU   A O   1 
ATOM   2259 C CB  . LEU   A 1 279 ? 132.237 144.623 144.479 1.00 63.57  ? 304 LEU   A CB  1 
ATOM   2260 C CG  . LEU   A 1 279 ? 131.579 144.956 143.140 1.00 67.43  ? 304 LEU   A CG  1 
ATOM   2261 C CD1 . LEU   A 1 279 ? 130.337 144.109 142.944 1.00 68.10  ? 304 LEU   A CD1 1 
ATOM   2262 C CD2 . LEU   A 1 279 ? 131.228 146.432 143.051 1.00 69.65  ? 304 LEU   A CD2 1 
ATOM   2263 N N   . ALA   A 1 280 ? 134.152 144.352 146.987 1.00 64.13  ? 305 ALA   A N   1 
ATOM   2264 C CA  . ALA   A 1 280 ? 134.401 144.453 148.421 1.00 61.28  ? 305 ALA   A CA  1 
ATOM   2265 C C   . ALA   A 1 280 ? 135.603 145.343 148.715 1.00 59.56  ? 305 ALA   A C   1 
ATOM   2266 O O   . ALA   A 1 280 ? 135.651 146.009 149.755 1.00 59.82  ? 305 ALA   A O   1 
ATOM   2267 C CB  . ALA   A 1 280 ? 134.608 143.063 149.015 1.00 63.92  ? 305 ALA   A CB  1 
ATOM   2268 N N   . SER   A 1 281 ? 136.597 145.343 147.826 1.00 60.84  ? 306 SER   A N   1 
ATOM   2269 C CA  . SER   A 1 281 ? 137.793 146.151 148.045 1.00 60.35  ? 306 SER   A CA  1 
ATOM   2270 C C   . SER   A 1 281 ? 137.548 147.629 147.769 1.00 59.45  ? 306 SER   A C   1 
ATOM   2271 O O   . SER   A 1 281 ? 138.255 148.479 148.316 1.00 65.78  ? 306 SER   A O   1 
ATOM   2272 C CB  . SER   A 1 281 ? 138.936 145.647 147.168 1.00 65.51  ? 306 SER   A CB  1 
ATOM   2273 O OG  . SER   A 1 281 ? 138.767 146.061 145.825 1.00 68.28  ? 306 SER   A OG  1 
ATOM   2274 N N   . SER   A 1 282 ? 136.592 147.954 146.900 1.00 61.15  ? 307 SER   A N   1 
ATOM   2275 C CA  . SER   A 1 282 ? 136.341 149.354 146.551 1.00 60.73  ? 307 SER   A CA  1 
ATOM   2276 C C   . SER   A 1 282 ? 136.011 150.240 147.750 1.00 54.65  ? 307 SER   A C   1 
ATOM   2277 O O   . SER   A 1 282 ? 136.555 151.352 147.827 1.00 56.97  ? 307 SER   A O   1 
ATOM   2278 C CB  . SER   A 1 282 ? 135.229 149.423 145.495 1.00 67.25  ? 307 SER   A CB  1 
ATOM   2279 O OG  . SER   A 1 282 ? 135.757 149.235 144.194 1.00 74.60  ? 307 SER   A OG  1 
ATOM   2280 N N   . PRO   A 1 283 ? 135.158 149.838 148.699 1.00 53.58  ? 308 PRO   A N   1 
ATOM   2281 C CA  . PRO   A 1 283 ? 134.908 150.691 149.874 1.00 50.56  ? 308 PRO   A CA  1 
ATOM   2282 C C   . PRO   A 1 283 ? 136.129 150.984 150.731 1.00 60.81  ? 308 PRO   A C   1 
ATOM   2283 O O   . PRO   A 1 283 ? 136.056 151.892 151.567 1.00 70.10  ? 308 PRO   A O   1 
ATOM   2284 C CB  . PRO   A 1 283 ? 133.874 149.890 150.671 1.00 54.04  ? 308 PRO   A CB  1 
ATOM   2285 C CG  . PRO   A 1 283 ? 133.152 149.118 149.670 1.00 60.49  ? 308 PRO   A CG  1 
ATOM   2286 C CD  . PRO   A 1 283 ? 134.124 148.797 148.572 1.00 63.85  ? 308 PRO   A CD  1 
ATOM   2287 N N   . LEU   A 1 284 ? 137.234 150.251 150.571 1.00 63.86  ? 309 LEU   A N   1 
ATOM   2288 C CA  . LEU   A 1 284 ? 138.396 150.455 151.434 1.00 59.75  ? 309 LEU   A CA  1 
ATOM   2289 C C   . LEU   A 1 284 ? 138.992 151.849 151.292 1.00 60.67  ? 309 LEU   A C   1 
ATOM   2290 O O   . LEU   A 1 284 ? 139.680 152.309 152.208 1.00 62.43  ? 309 LEU   A O   1 
ATOM   2291 C CB  . LEU   A 1 284 ? 139.471 149.407 151.131 1.00 56.42  ? 309 LEU   A CB  1 
ATOM   2292 C CG  . LEU   A 1 284 ? 140.144 148.713 152.308 1.00 65.74  ? 309 LEU   A CG  1 
ATOM   2293 C CD1 . LEU   A 1 284 ? 139.158 147.847 153.074 1.00 67.21  ? 309 LEU   A CD1 1 
ATOM   2294 C CD2 . LEU   A 1 284 ? 141.295 147.883 151.794 1.00 67.23  ? 309 LEU   A CD2 1 
ATOM   2295 N N   . PHE   A 1 285 ? 138.755 152.528 150.168 1.00 60.77  ? 310 PHE   A N   1 
ATOM   2296 C CA  . PHE   A 1 285 ? 139.232 153.890 149.977 1.00 56.81  ? 310 PHE   A CA  1 
ATOM   2297 C C   . PHE   A 1 285 ? 138.395 154.932 150.710 1.00 61.56  ? 310 PHE   A C   1 
ATOM   2298 O O   . PHE   A 1 285 ? 138.799 156.098 150.757 1.00 66.51  ? 310 PHE   A O   1 
ATOM   2299 C CB  . PHE   A 1 285 ? 139.264 154.225 148.487 1.00 56.33  ? 310 PHE   A CB  1 
ATOM   2300 C CG  . PHE   A 1 285 ? 140.332 153.501 147.724 1.00 54.31  ? 310 PHE   A CG  1 
ATOM   2301 C CD1 . PHE   A 1 285 ? 141.616 154.004 147.665 1.00 53.42  ? 310 PHE   A CD1 1 
ATOM   2302 C CD2 . PHE   A 1 285 ? 140.051 152.330 147.053 1.00 57.43  ? 310 PHE   A CD2 1 
ATOM   2303 C CE1 . PHE   A 1 285 ? 142.595 153.347 146.964 1.00 52.67  ? 310 PHE   A CE1 1 
ATOM   2304 C CE2 . PHE   A 1 285 ? 141.029 151.670 146.349 1.00 57.50  ? 310 PHE   A CE2 1 
ATOM   2305 C CZ  . PHE   A 1 285 ? 142.302 152.180 146.305 1.00 53.28  ? 310 PHE   A CZ  1 
ATOM   2306 N N   . CYS   A 1 286 ? 137.251 154.555 151.274 1.00 61.22  ? 311 CYS   A N   1 
ATOM   2307 C CA  . CYS   A 1 286 ? 136.426 155.497 152.011 1.00 62.21  ? 311 CYS   A CA  1 
ATOM   2308 C C   . CYS   A 1 286 ? 137.086 155.829 153.346 1.00 65.49  ? 311 CYS   A C   1 
ATOM   2309 O O   . CYS   A 1 286 ? 138.189 155.372 153.658 1.00 69.95  ? 311 CYS   A O   1 
ATOM   2310 C CB  . CYS   A 1 286 ? 135.027 154.925 152.221 1.00 62.00  ? 311 CYS   A CB  1 
ATOM   2311 S SG  . CYS   A 1 286 ? 134.189 154.435 150.701 1.00 80.84  ? 311 CYS   A SG  1 
ATOM   2312 N N   . SER   A 1 287 ? 136.410 156.653 154.139 1.00 66.34  ? 312 SER   A N   1 
ATOM   2313 C CA  . SER   A 1 287 ? 136.924 156.978 155.458 1.00 65.10  ? 312 SER   A CA  1 
ATOM   2314 C C   . SER   A 1 287 ? 136.982 155.707 156.306 1.00 67.68  ? 312 SER   A C   1 
ATOM   2315 O O   . SER   A 1 287 ? 136.101 154.849 156.183 1.00 75.09  ? 312 SER   A O   1 
ATOM   2316 C CB  . SER   A 1 287 ? 136.040 158.024 156.136 1.00 72.77  ? 312 SER   A CB  1 
ATOM   2317 O OG  . SER   A 1 287 ? 134.717 157.544 156.301 1.00 81.37  ? 312 SER   A OG  1 
ATOM   2318 N N   . PRO   A 1 288 ? 137.987 155.542 157.176 1.00 60.75  ? 313 PRO   A N   1 
ATOM   2319 C CA  . PRO   A 1 288 ? 138.111 154.267 157.901 1.00 59.93  ? 313 PRO   A CA  1 
ATOM   2320 C C   . PRO   A 1 288 ? 137.004 153.981 158.908 1.00 66.25  ? 313 PRO   A C   1 
ATOM   2321 O O   . PRO   A 1 288 ? 137.033 152.905 159.518 1.00 69.85  ? 313 PRO   A O   1 
ATOM   2322 C CB  . PRO   A 1 288 ? 139.460 154.402 158.625 1.00 58.02  ? 313 PRO   A CB  1 
ATOM   2323 C CG  . PRO   A 1 288 ? 140.160 155.497 157.965 1.00 60.04  ? 313 PRO   A CG  1 
ATOM   2324 C CD  . PRO   A 1 288 ? 139.113 156.436 157.501 1.00 64.14  ? 313 PRO   A CD  1 
ATOM   2325 N N   . GLU   A 1 289 ? 136.036 154.881 159.108 1.00 66.97  ? 314 GLU   A N   1 
ATOM   2326 C CA  . GLU   A 1 289 ? 135.019 154.736 160.145 1.00 66.88  ? 314 GLU   A CA  1 
ATOM   2327 C C   . GLU   A 1 289 ? 133.603 154.666 159.583 1.00 71.68  ? 314 GLU   A C   1 
ATOM   2328 O O   . GLU   A 1 289 ? 132.646 154.947 160.311 1.00 78.25  ? 314 GLU   A O   1 
ATOM   2329 C CB  . GLU   A 1 289 ? 135.129 155.889 161.146 1.00 71.16  ? 314 GLU   A CB  1 
ATOM   2330 C CG  . GLU   A 1 289 ? 134.924 157.270 160.547 1.00 79.86  ? 314 GLU   A CG  1 
ATOM   2331 C CD  . GLU   A 1 289 ? 135.156 158.378 161.553 1.00 94.85  ? 314 GLU   A CD  1 
ATOM   2332 O OE1 . GLU   A 1 289 ? 135.410 158.067 162.735 1.00 92.42  ? 314 GLU   A OE1 1 
ATOM   2333 O OE2 . GLU   A 1 289 ? 135.084 159.562 161.161 1.00 100.31 ? 314 GLU   A OE2 1 
ATOM   2334 N N   . TRP   A 1 290 ? 133.437 154.309 158.310 1.00 69.50  ? 315 TRP   A N   1 
ATOM   2335 C CA  . TRP   A 1 290 ? 132.087 154.254 157.752 1.00 70.65  ? 315 TRP   A CA  1 
ATOM   2336 C C   . TRP   A 1 290 ? 131.184 153.214 158.417 1.00 73.12  ? 315 TRP   A C   1 
ATOM   2337 O O   . TRP   A 1 290 ? 130.000 153.533 158.638 1.00 80.52  ? 315 TRP   A O   1 
ATOM   2338 C CB  . TRP   A 1 290 ? 132.138 154.073 156.225 1.00 73.73  ? 315 TRP   A CB  1 
ATOM   2339 C CG  . TRP   A 1 290 ? 132.703 152.795 155.693 1.00 73.17  ? 315 TRP   A CG  1 
ATOM   2340 C CD1 . TRP   A 1 290 ? 134.002 152.545 155.377 1.00 71.18  ? 315 TRP   A CD1 1 
ATOM   2341 C CD2 . TRP   A 1 290 ? 131.980 151.598 155.387 1.00 67.82  ? 315 TRP   A CD2 1 
ATOM   2342 N NE1 . TRP   A 1 290 ? 134.139 151.266 154.905 1.00 70.06  ? 315 TRP   A NE1 1 
ATOM   2343 C CE2 . TRP   A 1 290 ? 132.910 150.663 154.900 1.00 64.87  ? 315 TRP   A CE2 1 
ATOM   2344 C CE3 . TRP   A 1 290 ? 130.639 151.226 155.483 1.00 69.63  ? 315 TRP   A CE3 1 
ATOM   2345 C CZ2 . TRP   A 1 290 ? 132.544 149.382 154.512 1.00 65.77  ? 315 TRP   A CZ2 1 
ATOM   2346 C CZ3 . TRP   A 1 290 ? 130.277 149.953 155.097 1.00 68.96  ? 315 TRP   A CZ3 1 
ATOM   2347 C CH2 . TRP   A 1 290 ? 131.226 149.046 154.618 1.00 67.62  ? 315 TRP   A CH2 1 
ATOM   2348 N N   . PRO   A 1 291 ? 131.626 151.990 158.751 1.00 68.73  ? 316 PRO   A N   1 
ATOM   2349 C CA  . PRO   A 1 291 ? 130.686 151.068 159.406 1.00 69.07  ? 316 PRO   A CA  1 
ATOM   2350 C C   . PRO   A 1 291 ? 130.211 151.562 160.757 1.00 75.19  ? 316 PRO   A C   1 
ATOM   2351 O O   . PRO   A 1 291 ? 129.071 151.285 161.141 1.00 85.32  ? 316 PRO   A O   1 
ATOM   2352 C CB  . PRO   A 1 291 ? 131.494 149.766 159.529 1.00 69.03  ? 316 PRO   A CB  1 
ATOM   2353 C CG  . PRO   A 1 291 ? 132.667 149.945 158.638 1.00 72.70  ? 316 PRO   A CG  1 
ATOM   2354 C CD  . PRO   A 1 291 ? 132.970 151.391 158.757 1.00 73.10  ? 316 PRO   A CD  1 
ATOM   2355 N N   . ARG   A 1 292 ? 131.051 152.293 161.492 1.00 71.37  ? 317 ARG   A N   1 
ATOM   2356 C CA  . ARG   A 1 292 ? 130.645 152.792 162.801 1.00 72.49  ? 317 ARG   A CA  1 
ATOM   2357 C C   . ARG   A 1 292 ? 129.505 153.796 162.679 1.00 73.59  ? 317 ARG   A C   1 
ATOM   2358 O O   . ARG   A 1 292 ? 128.503 153.703 163.400 1.00 81.34  ? 317 ARG   A O   1 
ATOM   2359 C CB  . ARG   A 1 292 ? 131.846 153.412 163.514 1.00 70.55  ? 317 ARG   A CB  1 
ATOM   2360 C CG  . ARG   A 1 292 ? 131.533 153.966 164.890 1.00 74.01  ? 317 ARG   A CG  1 
ATOM   2361 C CD  . ARG   A 1 292 ? 132.787 154.335 165.659 1.00 73.56  ? 317 ARG   A CD  1 
ATOM   2362 N NE  . ARG   A 1 292 ? 133.517 153.162 166.133 1.00 70.81  ? 317 ARG   A NE  1 
ATOM   2363 C CZ  . ARG   A 1 292 ? 134.561 152.600 165.536 1.00 70.92  ? 317 ARG   A CZ  1 
ATOM   2364 N NH1 . ARG   A 1 292 ? 135.044 153.055 164.390 1.00 73.32  ? 317 ARG   A NH1 1 
ATOM   2365 N NH2 . ARG   A 1 292 ? 135.140 151.549 166.106 1.00 68.88  ? 317 ARG   A NH2 1 
ATOM   2366 N N   . LYS   A 1 293 ? 129.629 154.760 161.764 1.00 72.12  ? 318 LYS   A N   1 
ATOM   2367 C CA  . LYS   A 1 293 ? 128.548 155.720 161.581 1.00 77.92  ? 318 LYS   A CA  1 
ATOM   2368 C C   . LYS   A 1 293 ? 127.311 155.043 161.008 1.00 78.95  ? 318 LYS   A C   1 
ATOM   2369 O O   . LYS   A 1 293 ? 126.182 155.434 161.328 1.00 87.66  ? 318 LYS   A O   1 
ATOM   2370 C CB  . LYS   A 1 293 ? 128.998 156.884 160.694 1.00 84.28  ? 318 LYS   A CB  1 
ATOM   2371 C CG  . LYS   A 1 293 ? 129.327 156.523 159.259 1.00 87.19  ? 318 LYS   A CG  1 
ATOM   2372 C CD  . LYS   A 1 293 ? 129.747 157.746 158.456 1.00 90.88  ? 318 LYS   A CD  1 
ATOM   2373 C CE  . LYS   A 1 293 ? 129.789 157.442 156.964 1.00 89.92  ? 318 LYS   A CE  1 
ATOM   2374 N NZ  . LYS   A 1 293 ? 130.254 158.605 156.157 1.00 94.95  ? 318 LYS   A NZ  1 
ATOM   2375 N N   . LEU   A 1 294 ? 127.497 154.035 160.151 1.00 73.62  ? 319 LEU   A N   1 
ATOM   2376 C CA  . LEU   A 1 294 ? 126.345 153.281 159.664 1.00 77.20  ? 319 LEU   A CA  1 
ATOM   2377 C C   . LEU   A 1 294 ? 125.612 152.594 160.810 1.00 79.20  ? 319 LEU   A C   1 
ATOM   2378 O O   . LEU   A 1 294 ? 124.378 152.594 160.855 1.00 86.24  ? 319 LEU   A O   1 
ATOM   2379 C CB  . LEU   A 1 294 ? 126.777 152.253 158.617 1.00 81.38  ? 319 LEU   A CB  1 
ATOM   2380 C CG  . LEU   A 1 294 ? 126.513 152.636 157.158 1.00 83.96  ? 319 LEU   A CG  1 
ATOM   2381 C CD1 . LEU   A 1 294 ? 127.323 153.854 156.740 1.00 83.42  ? 319 LEU   A CD1 1 
ATOM   2382 C CD2 . LEU   A 1 294 ? 126.808 151.460 156.243 1.00 82.24  ? 319 LEU   A CD2 1 
ATOM   2383 N N   . VAL   A 1 295 ? 126.356 152.001 161.744 1.00 79.46  ? 320 VAL   A N   1 
ATOM   2384 C CA  . VAL   A 1 295 ? 125.732 151.359 162.898 1.00 81.57  ? 320 VAL   A CA  1 
ATOM   2385 C C   . VAL   A 1 295 ? 125.035 152.396 163.766 1.00 86.47  ? 320 VAL   A C   1 
ATOM   2386 O O   . VAL   A 1 295 ? 123.992 152.121 164.370 1.00 90.96  ? 320 VAL   A O   1 
ATOM   2387 C CB  . VAL   A 1 295 ? 126.777 150.559 163.699 1.00 83.80  ? 320 VAL   A CB  1 
ATOM   2388 C CG1 . VAL   A 1 295 ? 126.217 150.131 165.047 1.00 86.14  ? 320 VAL   A CG1 1 
ATOM   2389 C CG2 . VAL   A 1 295 ? 127.229 149.338 162.913 1.00 85.77  ? 320 VAL   A CG2 1 
ATOM   2390 N N   . SER   A 1 296 ? 125.607 153.599 163.858 1.00 89.86  ? 321 SER   A N   1 
ATOM   2391 C CA  . SER   A 1 296 ? 124.968 154.655 164.637 1.00 88.46  ? 321 SER   A CA  1 
ATOM   2392 C C   . SER   A 1 296 ? 123.614 155.034 164.049 1.00 86.42  ? 321 SER   A C   1 
ATOM   2393 O O   . SER   A 1 296 ? 122.653 155.269 164.789 1.00 90.69  ? 321 SER   A O   1 
ATOM   2394 C CB  . SER   A 1 296 ? 125.880 155.878 164.710 1.00 86.69  ? 321 SER   A CB  1 
ATOM   2395 O OG  . SER   A 1 296 ? 127.067 155.587 165.426 1.00 86.94  ? 321 SER   A OG  1 
ATOM   2396 N N   . TYR   A 1 297 ? 123.515 155.091 162.720 1.00 85.98  ? 322 TYR   A N   1 
ATOM   2397 C CA  . TYR   A 1 297 ? 122.276 155.475 162.042 1.00 89.77  ? 322 TYR   A CA  1 
ATOM   2398 C C   . TYR   A 1 297 ? 121.340 154.271 161.901 1.00 92.39  ? 322 TYR   A C   1 
ATOM   2399 O O   . TYR   A 1 297 ? 120.988 153.844 160.802 1.00 97.50  ? 322 TYR   A O   1 
ATOM   2400 C CB  . TYR   A 1 297 ? 122.583 156.077 160.675 1.00 92.31  ? 322 TYR   A CB  1 
ATOM   2401 C CG  . TYR   A 1 297 ? 123.518 157.271 160.672 1.00 98.07  ? 322 TYR   A CG  1 
ATOM   2402 C CD1 . TYR   A 1 297 ? 123.624 158.114 161.773 1.00 99.81  ? 322 TYR   A CD1 1 
ATOM   2403 C CD2 . TYR   A 1 297 ? 124.290 157.559 159.554 1.00 97.88  ? 322 TYR   A CD2 1 
ATOM   2404 C CE1 . TYR   A 1 297 ? 124.477 159.202 161.761 1.00 105.26 ? 322 TYR   A CE1 1 
ATOM   2405 C CE2 . TYR   A 1 297 ? 125.144 158.642 159.533 1.00 100.36 ? 322 TYR   A CE2 1 
ATOM   2406 C CZ  . TYR   A 1 297 ? 125.234 159.461 160.638 1.00 108.28 ? 322 TYR   A CZ  1 
ATOM   2407 O OH  . TYR   A 1 297 ? 126.083 160.544 160.621 1.00 109.81 ? 322 TYR   A OH  1 
ATOM   2408 N N   . CYS   A 1 298 ? 120.941 153.723 163.043 1.00 91.33  ? 323 CYS   A N   1 
ATOM   2409 C CA  . CYS   A 1 298 ? 120.022 152.595 163.083 1.00 99.17  ? 323 CYS   A CA  1 
ATOM   2410 C C   . CYS   A 1 298 ? 119.171 152.707 164.338 1.00 106.20 ? 323 CYS   A C   1 
ATOM   2411 O O   . CYS   A 1 298 ? 119.531 153.435 165.271 1.00 105.62 ? 323 CYS   A O   1 
ATOM   2412 C CB  . CYS   A 1 298 ? 120.770 151.256 163.066 1.00 104.75 ? 323 CYS   A CB  1 
ATOM   2413 S SG  . CYS   A 1 298 ? 121.330 150.735 161.430 1.00 113.34 ? 323 CYS   A SG  1 
ATOM   2414 N N   . PRO   A 1 299 ? 118.036 152.008 164.396 1.00 113.21 ? 324 PRO   A N   1 
ATOM   2415 C CA  . PRO   A 1 299 ? 117.265 151.977 165.643 1.00 115.53 ? 324 PRO   A CA  1 
ATOM   2416 C C   . PRO   A 1 299 ? 118.026 151.257 166.744 1.00 118.02 ? 324 PRO   A C   1 
ATOM   2417 O O   . PRO   A 1 299 ? 118.966 150.497 166.500 1.00 118.37 ? 324 PRO   A O   1 
ATOM   2418 C CB  . PRO   A 1 299 ? 115.991 151.213 165.267 1.00 117.78 ? 324 PRO   A CB  1 
ATOM   2419 C CG  . PRO   A 1 299 ? 115.904 151.296 163.795 1.00 117.23 ? 324 PRO   A CG  1 
ATOM   2420 C CD  . PRO   A 1 299 ? 117.312 151.334 163.303 1.00 113.27 ? 324 PRO   A CD  1 
ATOM   2421 N N   . ARG   A 1 300 ? 117.602 151.516 167.983 1.00 118.46 ? 325 ARG   A N   1 
ATOM   2422 C CA  . ARG   A 1 300 ? 118.278 150.927 169.134 1.00 118.21 ? 325 ARG   A CA  1 
ATOM   2423 C C   . ARG   A 1 300 ? 118.176 149.407 169.131 1.00 113.63 ? 325 ARG   A C   1 
ATOM   2424 O O   . ARG   A 1 300 ? 119.069 148.728 169.649 1.00 113.45 ? 325 ARG   A O   1 
ATOM   2425 C CB  . ARG   A 1 300 ? 117.697 151.492 170.431 1.00 120.71 ? 325 ARG   A CB  1 
ATOM   2426 C CG  . ARG   A 1 300 ? 118.589 151.308 171.654 1.00 122.58 ? 325 ARG   A CG  1 
ATOM   2427 C CD  . ARG   A 1 300 ? 119.783 152.254 171.631 1.00 123.37 ? 325 ARG   A CD  1 
ATOM   2428 N NE  . ARG   A 1 300 ? 120.596 152.148 172.838 1.00 126.22 ? 325 ARG   A NE  1 
ATOM   2429 C CZ  . ARG   A 1 300 ? 121.719 152.820 173.058 1.00 123.53 ? 325 ARG   A CZ  1 
ATOM   2430 N NH1 . ARG   A 1 300 ? 122.210 153.669 172.167 1.00 120.08 ? 325 ARG   A NH1 1 
ATOM   2431 N NH2 . ARG   A 1 300 ? 122.371 152.635 174.202 1.00 120.60 ? 325 ARG   A NH2 1 
ATOM   2432 N N   . ARG   A 1 301 ? 117.096 148.857 168.571 1.00 114.19 ? 326 ARG   A N   1 
ATOM   2433 C CA  . ARG   A 1 301 ? 116.949 147.406 168.521 1.00 118.37 ? 326 ARG   A CA  1 
ATOM   2434 C C   . ARG   A 1 301 ? 118.067 146.764 167.709 1.00 117.17 ? 326 ARG   A C   1 
ATOM   2435 O O   . ARG   A 1 301 ? 118.620 145.733 168.108 1.00 116.05 ? 326 ARG   A O   1 
ATOM   2436 C CB  . ARG   A 1 301 ? 115.584 147.040 167.939 1.00 125.95 ? 326 ARG   A CB  1 
ATOM   2437 C CG  . ARG   A 1 301 ? 114.409 147.534 168.768 1.00 130.64 ? 326 ARG   A CG  1 
ATOM   2438 C CD  . ARG   A 1 301 ? 113.079 147.157 168.137 1.00 135.12 ? 326 ARG   A CD  1 
ATOM   2439 N NE  . ARG   A 1 301 ? 111.949 147.657 168.912 1.00 139.04 ? 326 ARG   A NE  1 
ATOM   2440 C CZ  . ARG   A 1 301 ? 110.673 147.498 168.586 1.00 140.18 ? 326 ARG   A CZ  1 
ATOM   2441 N NH1 . ARG   A 1 301 ? 110.308 146.847 167.491 1.00 139.55 ? 326 ARG   A NH1 1 
ATOM   2442 N NH2 . ARG   A 1 301 ? 109.734 148.005 169.380 1.00 138.83 ? 326 ARG   A NH2 1 
ATOM   2443 N N   . LEU   A 1 302 ? 118.411 147.354 166.563 1.00 117.99 ? 327 LEU   A N   1 
ATOM   2444 C CA  . LEU   A 1 302 ? 119.515 146.824 165.769 1.00 117.69 ? 327 LEU   A CA  1 
ATOM   2445 C C   . LEU   A 1 302 ? 120.847 147.001 166.486 1.00 115.96 ? 327 LEU   A C   1 
ATOM   2446 O O   . LEU   A 1 302 ? 121.724 146.135 166.396 1.00 114.88 ? 327 LEU   A O   1 
ATOM   2447 C CB  . LEU   A 1 302 ? 119.555 147.498 164.395 1.00 118.22 ? 327 LEU   A CB  1 
ATOM   2448 C CG  . LEU   A 1 302 ? 118.385 147.250 163.433 1.00 120.39 ? 327 LEU   A CG  1 
ATOM   2449 C CD1 . LEU   A 1 302 ? 118.619 147.976 162.114 1.00 116.50 ? 327 LEU   A CD1 1 
ATOM   2450 C CD2 . LEU   A 1 302 ? 118.166 145.766 163.176 1.00 118.71 ? 327 LEU   A CD2 1 
ATOM   2451 N N   . GLN   A 1 303 ? 121.020 148.117 167.201 1.00 112.90 ? 328 GLN   A N   1 
ATOM   2452 C CA  . GLN   A 1 303 ? 122.283 148.370 167.888 1.00 107.27 ? 328 GLN   A CA  1 
ATOM   2453 C C   . GLN   A 1 303 ? 122.580 147.332 168.961 1.00 107.26 ? 328 GLN   A C   1 
ATOM   2454 O O   . GLN   A 1 303 ? 123.747 147.153 169.325 1.00 107.24 ? 328 GLN   A O   1 
ATOM   2455 C CB  . GLN   A 1 303 ? 122.279 149.765 168.511 1.00 105.13 ? 328 GLN   A CB  1 
ATOM   2456 C CG  . GLN   A 1 303 ? 122.365 150.892 167.501 1.00 105.44 ? 328 GLN   A CG  1 
ATOM   2457 C CD  . GLN   A 1 303 ? 122.584 152.243 168.151 1.00 108.31 ? 328 GLN   A CD  1 
ATOM   2458 O OE1 . GLN   A 1 303 ? 122.896 152.332 169.338 1.00 111.02 ? 328 GLN   A OE1 1 
ATOM   2459 N NE2 . GLN   A 1 303 ? 122.420 153.307 167.373 1.00 105.64 ? 328 GLN   A NE2 1 
ATOM   2460 N N   . GLN   A 1 304 ? 121.561 146.644 169.475 1.00 110.85 ? 329 GLN   A N   1 
ATOM   2461 C CA  . GLN   A 1 304 ? 121.789 145.586 170.450 1.00 109.31 ? 329 GLN   A CA  1 
ATOM   2462 C C   . GLN   A 1 304 ? 122.404 144.336 169.835 1.00 106.19 ? 329 GLN   A C   1 
ATOM   2463 O O   . GLN   A 1 304 ? 122.829 143.452 170.587 1.00 106.97 ? 329 GLN   A O   1 
ATOM   2464 C CB  . GLN   A 1 304 ? 120.475 145.221 171.138 1.00 114.85 ? 329 GLN   A CB  1 
ATOM   2465 C CG  . GLN   A 1 304 ? 119.898 146.332 172.000 1.00 121.24 ? 329 GLN   A CG  1 
ATOM   2466 C CD  . GLN   A 1 304 ? 118.529 145.988 172.552 1.00 126.82 ? 329 GLN   A CD  1 
ATOM   2467 O OE1 . GLN   A 1 304 ? 118.041 144.871 172.380 1.00 130.44 ? 329 GLN   A OE1 1 
ATOM   2468 N NE2 . GLN   A 1 304 ? 117.900 146.949 173.218 1.00 126.03 ? 329 GLN   A NE2 1 
ATOM   2469 N N   . LEU   A 1 305 ? 122.460 144.238 168.505 1.00 108.90 ? 330 LEU   A N   1 
ATOM   2470 C CA  . LEU   A 1 305 ? 123.044 143.098 167.810 1.00 113.47 ? 330 LEU   A CA  1 
ATOM   2471 C C   . LEU   A 1 305 ? 124.267 143.449 166.976 1.00 108.55 ? 330 LEU   A C   1 
ATOM   2472 O O   . LEU   A 1 305 ? 125.153 142.606 166.827 1.00 107.94 ? 330 LEU   A O   1 
ATOM   2473 C CB  . LEU   A 1 305 ? 122.000 142.445 166.890 1.00 116.51 ? 330 LEU   A CB  1 
ATOM   2474 C CG  . LEU   A 1 305 ? 120.677 142.029 167.540 1.00 117.96 ? 330 LEU   A CG  1 
ATOM   2475 C CD1 . LEU   A 1 305 ? 119.728 141.472 166.491 1.00 117.27 ? 330 LEU   A CD1 1 
ATOM   2476 C CD2 . LEU   A 1 305 ? 120.904 141.014 168.651 1.00 114.75 ? 330 LEU   A CD2 1 
ATOM   2477 N N   . LEU   A 1 306 ? 124.340 144.659 166.434 1.00 100.00 ? 331 LEU   A N   1 
ATOM   2478 C CA  . LEU   A 1 306 ? 125.457 145.063 165.597 1.00 91.97  ? 331 LEU   A CA  1 
ATOM   2479 C C   . LEU   A 1 306 ? 126.672 145.379 166.465 1.00 89.56  ? 331 LEU   A C   1 
ATOM   2480 O O   . LEU   A 1 306 ? 126.562 145.489 167.688 1.00 87.93  ? 331 LEU   A O   1 
ATOM   2481 C CB  . LEU   A 1 306 ? 125.048 146.266 164.750 1.00 94.44  ? 331 LEU   A CB  1 
ATOM   2482 C CG  . LEU   A 1 306 ? 123.876 146.058 163.787 1.00 97.61  ? 331 LEU   A CG  1 
ATOM   2483 C CD1 . LEU   A 1 306 ? 123.541 147.358 163.072 1.00 98.70  ? 331 LEU   A CD1 1 
ATOM   2484 C CD2 . LEU   A 1 306 ? 124.168 144.959 162.775 1.00 94.56  ? 331 LEU   A CD2 1 
ATOM   2485 N N   . PRO   A 1 307 ? 127.859 145.508 165.866 1.00 86.39  ? 332 PRO   A N   1 
ATOM   2486 C CA  . PRO   A 1 307 ? 129.058 145.808 166.660 1.00 87.46  ? 332 PRO   A CA  1 
ATOM   2487 C C   . PRO   A 1 307 ? 128.953 147.133 167.404 1.00 90.07  ? 332 PRO   A C   1 
ATOM   2488 O O   . PRO   A 1 307 ? 128.026 147.925 167.222 1.00 90.72  ? 332 PRO   A O   1 
ATOM   2489 C CB  . PRO   A 1 307 ? 130.175 145.848 165.614 1.00 82.51  ? 332 PRO   A CB  1 
ATOM   2490 C CG  . PRO   A 1 307 ? 129.690 145.002 164.518 1.00 77.09  ? 332 PRO   A CG  1 
ATOM   2491 C CD  . PRO   A 1 307 ? 128.211 145.202 164.467 1.00 82.96  ? 332 PRO   A CD  1 
ATOM   2492 N N   . LEU   A 1 308 ? 129.943 147.363 168.264 1.00 86.00  ? 333 LEU   A N   1 
ATOM   2493 C CA  . LEU   A 1 308 ? 129.951 148.535 169.127 1.00 84.58  ? 333 LEU   A CA  1 
ATOM   2494 C C   . LEU   A 1 308 ? 130.070 149.820 168.315 1.00 86.12  ? 333 LEU   A C   1 
ATOM   2495 O O   . LEU   A 1 308 ? 130.609 149.834 167.206 1.00 87.75  ? 333 LEU   A O   1 
ATOM   2496 C CB  . LEU   A 1 308 ? 131.106 148.453 170.123 1.00 82.96  ? 333 LEU   A CB  1 
ATOM   2497 C CG  . LEU   A 1 308 ? 131.152 147.234 171.045 1.00 90.41  ? 333 LEU   A CG  1 
ATOM   2498 C CD1 . LEU   A 1 308 ? 132.386 147.298 171.928 1.00 86.62  ? 333 LEU   A CD1 1 
ATOM   2499 C CD2 . LEU   A 1 308 ? 129.893 147.131 171.893 1.00 92.10  ? 333 LEU   A CD2 1 
ATOM   2500 N N   . LYS   A 1 309 ? 129.555 150.909 168.891 1.00 83.42  ? 334 LYS   A N   1 
ATOM   2501 C CA  . LYS   A 1 309 ? 129.611 152.235 168.290 1.00 85.62  ? 334 LYS   A CA  1 
ATOM   2502 C C   . LYS   A 1 309 ? 130.505 153.204 169.052 1.00 84.00  ? 334 LYS   A C   1 
ATOM   2503 O O   . LYS   A 1 309 ? 130.714 154.327 168.581 1.00 85.28  ? 334 LYS   A O   1 
ATOM   2504 C CB  . LYS   A 1 309 ? 128.199 152.825 168.186 1.00 90.42  ? 334 LYS   A CB  1 
ATOM   2505 C CG  . LYS   A 1 309 ? 127.472 152.981 169.515 1.00 95.84  ? 334 LYS   A CG  1 
ATOM   2506 C CD  . LYS   A 1 309 ? 126.121 153.650 169.326 1.00 101.22 ? 334 LYS   A CD  1 
ATOM   2507 C CE  . LYS   A 1 309 ? 125.465 153.968 170.660 1.00 106.80 ? 334 LYS   A CE  1 
ATOM   2508 N NZ  . LYS   A 1 309 ? 125.200 152.744 171.466 1.00 108.66 ? 334 LYS   A NZ  1 
ATOM   2509 N N   . ALA   A 1 310 ? 131.038 152.813 170.205 1.00 78.06  ? 335 ALA   A N   1 
ATOM   2510 C CA  . ALA   A 1 310 ? 131.876 153.713 170.978 1.00 73.39  ? 335 ALA   A CA  1 
ATOM   2511 C C   . ALA   A 1 310 ? 133.215 153.927 170.280 1.00 72.63  ? 335 ALA   A C   1 
ATOM   2512 O O   . ALA   A 1 310 ? 133.603 153.186 169.374 1.00 77.49  ? 335 ALA   A O   1 
ATOM   2513 C CB  . ALA   A 1 310 ? 132.098 153.161 172.385 1.00 73.87  ? 335 ALA   A CB  1 
ATOM   2514 N N   . ALA   A 1 311 ? 133.926 154.963 170.715 1.00 68.06  ? 336 ALA   A N   1 
ATOM   2515 C CA  . ALA   A 1 311 ? 135.207 155.281 170.113 1.00 64.77  ? 336 ALA   A CA  1 
ATOM   2516 C C   . ALA   A 1 311 ? 136.239 154.207 170.467 1.00 64.40  ? 336 ALA   A C   1 
ATOM   2517 O O   . ALA   A 1 311 ? 136.181 153.618 171.549 1.00 67.16  ? 336 ALA   A O   1 
ATOM   2518 C CB  . ALA   A 1 311 ? 135.697 156.644 170.587 1.00 65.07  ? 336 ALA   A CB  1 
ATOM   2519 N N   . PRO   A 1 312 ? 137.193 153.929 169.577 1.00 60.61  ? 337 PRO   A N   1 
ATOM   2520 C CA  . PRO   A 1 312 ? 138.177 152.883 169.871 1.00 61.76  ? 337 PRO   A CA  1 
ATOM   2521 C C   . PRO   A 1 312 ? 139.122 153.283 170.991 1.00 63.52  ? 337 PRO   A C   1 
ATOM   2522 O O   . PRO   A 1 312 ? 139.354 154.467 171.247 1.00 65.76  ? 337 PRO   A O   1 
ATOM   2523 C CB  . PRO   A 1 312 ? 138.927 152.720 168.547 1.00 63.64  ? 337 PRO   A CB  1 
ATOM   2524 C CG  . PRO   A 1 312 ? 138.787 154.022 167.885 1.00 65.57  ? 337 PRO   A CG  1 
ATOM   2525 C CD  . PRO   A 1 312 ? 137.440 154.536 168.257 1.00 64.21  ? 337 PRO   A CD  1 
ATOM   2526 N N   . GLN   A 1 313 ? 139.675 152.268 171.661 1.00 59.12  ? 338 GLN   A N   1 
ATOM   2527 C CA  . GLN   A 1 313 ? 140.575 152.473 172.783 1.00 60.85  ? 338 GLN   A CA  1 
ATOM   2528 C C   . GLN   A 1 313 ? 142.023 152.539 172.312 1.00 66.95  ? 338 GLN   A C   1 
ATOM   2529 O O   . GLN   A 1 313 ? 142.339 152.136 171.189 1.00 70.96  ? 338 GLN   A O   1 
ATOM   2530 C CB  . GLN   A 1 313 ? 140.409 151.349 173.806 1.00 65.36  ? 338 GLN   A CB  1 
ATOM   2531 C CG  . GLN   A 1 313 ? 140.769 149.951 173.313 1.00 67.30  ? 338 GLN   A CG  1 
ATOM   2532 C CD  . GLN   A 1 313 ? 140.651 148.910 174.403 1.00 68.26  ? 338 GLN   A CD  1 
ATOM   2533 O OE1 . GLN   A 1 313 ? 139.742 148.959 175.227 1.00 68.33  ? 338 GLN   A OE1 1 
ATOM   2534 N NE2 . GLN   A 1 313 ? 141.581 147.966 174.418 1.00 72.40  ? 338 GLN   A NE2 1 
ATOM   2535 N N   . PRO   A 1 314 ? 142.935 153.052 173.142 1.00 64.31  ? 339 PRO   A N   1 
ATOM   2536 C CA  . PRO   A 1 314 ? 144.356 153.006 172.782 1.00 64.06  ? 339 PRO   A CA  1 
ATOM   2537 C C   . PRO   A 1 314 ? 144.858 151.579 172.630 1.00 65.49  ? 339 PRO   A C   1 
ATOM   2538 O O   . PRO   A 1 314 ? 144.401 150.660 173.313 1.00 67.47  ? 339 PRO   A O   1 
ATOM   2539 C CB  . PRO   A 1 314 ? 145.045 153.712 173.955 1.00 65.85  ? 339 PRO   A CB  1 
ATOM   2540 C CG  . PRO   A 1 314 ? 144.006 154.566 174.548 1.00 67.66  ? 339 PRO   A CG  1 
ATOM   2541 C CD  . PRO   A 1 314 ? 142.719 153.828 174.376 1.00 64.34  ? 339 PRO   A CD  1 
ATOM   2542 N N   . SER   A 1 315 ? 145.810 151.406 171.721 1.00 68.09  ? 340 SER   A N   1 
ATOM   2543 C CA  . SER   A 1 315 ? 146.461 150.131 171.446 1.00 69.39  ? 340 SER   A CA  1 
ATOM   2544 C C   . SER   A 1 315 ? 147.956 150.252 171.721 1.00 73.33  ? 340 SER   A C   1 
ATOM   2545 O O   . SER   A 1 315 ? 148.464 151.324 172.059 1.00 75.50  ? 340 SER   A O   1 
ATOM   2546 C CB  . SER   A 1 315 ? 146.215 149.693 170.002 1.00 71.23  ? 340 SER   A CB  1 
ATOM   2547 O OG  . SER   A 1 315 ? 146.934 148.510 169.705 1.00 76.74  ? 340 SER   A OG  1 
ATOM   2548 N N   . VAL   A 1 316 ? 148.659 149.126 171.562 1.00 76.81  ? 341 VAL   A N   1 
ATOM   2549 C CA  . VAL   A 1 316 ? 150.103 149.065 171.781 1.00 77.17  ? 341 VAL   A CA  1 
ATOM   2550 C C   . VAL   A 1 316 ? 150.894 149.011 170.480 1.00 76.83  ? 341 VAL   A C   1 
ATOM   2551 O O   . VAL   A 1 316 ? 152.128 149.139 170.518 1.00 77.70  ? 341 VAL   A O   1 
ATOM   2552 C CB  . VAL   A 1 316 ? 150.469 147.852 172.666 1.00 83.02  ? 341 VAL   A CB  1 
ATOM   2553 C CG1 . VAL   A 1 316 ? 150.338 146.545 171.882 1.00 86.19  ? 341 VAL   A CG1 1 
ATOM   2554 C CG2 . VAL   A 1 316 ? 151.870 148.002 173.262 1.00 83.03  ? 341 VAL   A CG2 1 
ATOM   2555 N N   . SER   A 1 317 ? 150.230 148.856 169.332 1.00 78.28  ? 342 SER   A N   1 
ATOM   2556 C CA  . SER   A 1 317 ? 150.888 148.755 168.036 1.00 80.25  ? 342 SER   A CA  1 
ATOM   2557 C C   . SER   A 1 317 ? 150.842 150.068 167.261 1.00 81.48  ? 342 SER   A C   1 
ATOM   2558 O O   . SER   A 1 317 ? 150.788 150.056 166.026 1.00 79.82  ? 342 SER   A O   1 
ATOM   2559 C CB  . SER   A 1 317 ? 150.253 147.634 167.217 1.00 81.52  ? 342 SER   A CB  1 
ATOM   2560 O OG  . SER   A 1 317 ? 148.880 147.885 166.987 1.00 77.39  ? 342 SER   A OG  1 
ATOM   2561 N N   . CYS   A 1 318 ? 150.855 151.201 167.962 1.00 79.83  ? 343 CYS   A N   1 
ATOM   2562 C CA  . CYS   A 1 318 ? 150.800 152.515 167.337 1.00 75.43  ? 343 CYS   A CA  1 
ATOM   2563 C C   . CYS   A 1 318 ? 151.720 153.471 168.081 1.00 77.94  ? 343 CYS   A C   1 
ATOM   2564 O O   . CYS   A 1 318 ? 152.011 153.281 169.265 1.00 81.09  ? 343 CYS   A O   1 
ATOM   2565 C CB  . CYS   A 1 318 ? 149.375 153.069 167.327 1.00 73.49  ? 343 CYS   A CB  1 
ATOM   2566 S SG  . CYS   A 1 318 ? 148.194 152.054 166.425 1.00 80.55  ? 343 CYS   A SG  1 
ATOM   2567 N N   . VAL   A 1 319 ? 152.173 154.501 167.371 1.00 74.94  ? 344 VAL   A N   1 
ATOM   2568 C CA  . VAL   A 1 319 ? 153.016 155.552 167.932 1.00 77.04  ? 344 VAL   A CA  1 
ATOM   2569 C C   . VAL   A 1 319 ? 152.134 156.761 168.203 1.00 78.49  ? 344 VAL   A C   1 
ATOM   2570 O O   . VAL   A 1 319 ? 151.487 157.282 167.287 1.00 81.08  ? 344 VAL   A O   1 
ATOM   2571 C CB  . VAL   A 1 319 ? 154.169 155.913 166.984 1.00 80.39  ? 344 VAL   A CB  1 
ATOM   2572 C CG1 . VAL   A 1 319 ? 155.109 156.920 167.642 1.00 85.75  ? 344 VAL   A CG1 1 
ATOM   2573 C CG2 . VAL   A 1 319 ? 154.923 154.659 166.559 1.00 79.32  ? 344 VAL   A CG2 1 
ATOM   2574 N N   . TYR   A 1 320 ? 152.113 157.213 169.454 1.00 78.04  ? 345 TYR   A N   1 
ATOM   2575 C CA  . TYR   A 1 320 ? 151.246 158.296 169.897 1.00 80.27  ? 345 TYR   A CA  1 
ATOM   2576 C C   . TYR   A 1 320 ? 152.059 159.565 170.100 1.00 90.37  ? 345 TYR   A C   1 
ATOM   2577 O O   . TYR   A 1 320 ? 153.081 159.548 170.794 1.00 98.33  ? 345 TYR   A O   1 
ATOM   2578 C CB  . TYR   A 1 320 ? 150.528 157.918 171.193 1.00 80.15  ? 345 TYR   A CB  1 
ATOM   2579 C CG  . TYR   A 1 320 ? 149.401 156.938 170.982 1.00 73.29  ? 345 TYR   A CG  1 
ATOM   2580 C CD1 . TYR   A 1 320 ? 149.635 155.575 170.976 1.00 72.98  ? 345 TYR   A CD1 1 
ATOM   2581 C CD2 . TYR   A 1 320 ? 148.105 157.380 170.778 1.00 70.78  ? 345 TYR   A CD2 1 
ATOM   2582 C CE1 . TYR   A 1 320 ? 148.610 154.681 170.776 1.00 72.03  ? 345 TYR   A CE1 1 
ATOM   2583 C CE2 . TYR   A 1 320 ? 147.077 156.494 170.577 1.00 69.69  ? 345 TYR   A CE2 1 
ATOM   2584 C CZ  . TYR   A 1 320 ? 147.333 155.146 170.579 1.00 71.33  ? 345 TYR   A CZ  1 
ATOM   2585 O OH  . TYR   A 1 320 ? 146.307 154.257 170.376 1.00 76.32  ? 345 TYR   A OH  1 
ATOM   2586 N N   . LYS   A 1 321 ? 151.600 160.659 169.499 1.00 96.82  ? 346 LYS   A N   1 
ATOM   2587 C CA  . LYS   A 1 321 ? 152.234 161.958 169.662 1.00 101.10 ? 346 LYS   A CA  1 
ATOM   2588 C C   . LYS   A 1 321 ? 151.703 162.638 170.916 1.00 101.51 ? 346 LYS   A C   1 
ATOM   2589 O O   . LYS   A 1 321 ? 150.500 162.611 171.188 1.00 98.15  ? 346 LYS   A O   1 
ATOM   2590 C CB  . LYS   A 1 321 ? 151.979 162.841 168.440 1.00 102.61 ? 346 LYS   A CB  1 
ATOM   2591 C CG  . LYS   A 1 321 ? 152.542 162.285 167.142 1.00 105.96 ? 346 LYS   A CG  1 
ATOM   2592 C CD  . LYS   A 1 321 ? 152.316 163.243 165.983 1.00 108.13 ? 346 LYS   A CD  1 
ATOM   2593 C CE  . LYS   A 1 321 ? 152.872 162.686 164.682 1.00 108.06 ? 346 LYS   A CE  1 
ATOM   2594 N NZ  . LYS   A 1 321 ? 152.697 163.632 163.545 1.00 107.57 ? 346 LYS   A NZ  1 
ATOM   2595 N N   . ARG   A 1 322 ? 152.613 163.244 171.674 1.00 110.14 ? 347 ARG   A N   1 
ATOM   2596 C CA  . ARG   A 1 322 ? 152.270 163.945 172.909 1.00 115.85 ? 347 ARG   A CA  1 
ATOM   2597 C C   . ARG   A 1 322 ? 152.807 165.370 172.882 1.00 107.05 ? 347 ARG   A C   1 
ATOM   2598 O O   . ARG   A 1 322 ? 153.413 165.796 171.899 1.00 102.16 ? 347 ARG   A O   1 
ATOM   2599 C CB  . ARG   A 1 322 ? 152.827 163.197 174.122 1.00 121.06 ? 347 ARG   A CB  1 
ATOM   2600 C CG  . ARG   A 1 322 ? 152.274 161.789 174.292 1.00 120.84 ? 347 ARG   A CG  1 
ATOM   2601 C CD  . ARG   A 1 322 ? 152.906 161.078 175.479 1.00 125.45 ? 347 ARG   A CD  1 
ATOM   2602 N NE  . ARG   A 1 322 ? 152.631 161.758 176.740 1.00 132.33 ? 347 ARG   A NE  1 
ATOM   2603 C CZ  . ARG   A 1 322 ? 153.089 161.375 177.926 1.00 133.37 ? 347 ARG   A CZ  1 
ATOM   2604 N NH1 . ARG   A 1 322 ? 153.861 160.307 178.064 1.00 131.13 ? 347 ARG   A NH1 1 
ATOM   2605 N NH2 . ARG   A 1 322 ? 152.765 162.082 179.004 1.00 133.75 ? 347 ARG   A NH2 1 
ATOM   2606 N N   . GLY   A 1 328 ? 157.007 162.906 173.393 1.00 116.00 ? 353 GLY   A N   1 
ATOM   2607 C CA  . GLY   A 1 328 ? 156.744 161.944 172.339 1.00 112.00 ? 353 GLY   A CA  1 
ATOM   2608 C C   . GLY   A 1 328 ? 157.107 160.527 172.737 1.00 108.92 ? 353 GLY   A C   1 
ATOM   2609 O O   . GLY   A 1 328 ? 157.680 160.303 173.804 1.00 110.80 ? 353 GLY   A O   1 
ATOM   2610 N N   . GLN   A 1 329 ? 156.771 159.574 171.872 1.00 106.78 ? 354 GLN   A N   1 
ATOM   2611 C CA  . GLN   A 1 329 ? 157.039 158.159 172.090 1.00 106.18 ? 354 GLN   A CA  1 
ATOM   2612 C C   . GLN   A 1 329 ? 158.101 157.695 171.103 1.00 104.29 ? 354 GLN   A C   1 
ATOM   2613 O O   . GLN   A 1 329 ? 157.976 157.930 169.896 1.00 104.26 ? 354 GLN   A O   1 
ATOM   2614 C CB  . GLN   A 1 329 ? 155.762 157.332 171.924 1.00 105.33 ? 354 GLN   A CB  1 
ATOM   2615 C CG  . GLN   A 1 329 ? 155.924 155.848 172.225 1.00 107.47 ? 354 GLN   A CG  1 
ATOM   2616 C CD  . GLN   A 1 329 ? 154.618 155.086 172.114 1.00 112.26 ? 354 GLN   A CD  1 
ATOM   2617 O OE1 . GLN   A 1 329 ? 153.544 155.681 172.029 1.00 111.00 ? 354 GLN   A OE1 1 
ATOM   2618 N NE2 . GLN   A 1 329 ? 154.705 153.761 172.110 1.00 111.08 ? 354 GLN   A NE2 1 
ATOM   2619 N N   . LYS   A 1 330 ? 159.137 157.044 171.615 1.00 99.29  ? 355 LYS   A N   1 
ATOM   2620 C CA  . LYS   A 1 330 ? 160.190 156.516 170.760 1.00 96.89  ? 355 LYS   A CA  1 
ATOM   2621 C C   . LYS   A 1 330 ? 159.674 155.269 170.045 1.00 98.89  ? 355 LYS   A C   1 
ATOM   2622 O O   . LYS   A 1 330 ? 159.233 154.330 170.718 1.00 101.70 ? 355 LYS   A O   1 
ATOM   2623 C CB  . LYS   A 1 330 ? 161.422 156.175 171.586 1.00 98.05  ? 355 LYS   A CB  1 
ATOM   2624 C CG  . LYS   A 1 330 ? 162.630 155.748 170.764 1.00 103.91 ? 355 LYS   A CG  1 
ATOM   2625 C CD  . LYS   A 1 330 ? 163.846 155.515 171.647 1.00 111.05 ? 355 LYS   A CD  1 
ATOM   2626 C CE  . LYS   A 1 330 ? 165.039 155.033 170.837 1.00 111.38 ? 355 LYS   A CE  1 
ATOM   2627 N NZ  . LYS   A 1 330 ? 166.233 154.787 171.691 1.00 114.68 ? 355 LYS   A NZ  1 
ATOM   2628 N N   . PRO   A 1 331 ? 159.682 155.214 168.707 1.00 92.44  ? 356 PRO   A N   1 
ATOM   2629 C CA  . PRO   A 1 331 ? 159.248 153.983 168.037 1.00 86.17  ? 356 PRO   A CA  1 
ATOM   2630 C C   . PRO   A 1 331 ? 160.130 152.798 168.402 1.00 90.05  ? 356 PRO   A C   1 
ATOM   2631 O O   . PRO   A 1 331 ? 161.346 152.928 168.558 1.00 93.62  ? 356 PRO   A O   1 
ATOM   2632 C CB  . PRO   A 1 331 ? 159.359 154.328 166.549 1.00 84.13  ? 356 PRO   A CB  1 
ATOM   2633 C CG  . PRO   A 1 331 ? 159.237 155.783 166.493 1.00 87.91  ? 356 PRO   A CG  1 
ATOM   2634 C CD  . PRO   A 1 331 ? 159.903 156.294 167.726 1.00 93.38  ? 356 PRO   A CD  1 
ATOM   2635 N N   . GLY   A 1 332 ? 159.499 151.635 168.535 1.00 90.76  ? 357 GLY   A N   1 
ATOM   2636 C CA  . GLY   A 1 332 ? 160.205 150.411 168.856 1.00 86.84  ? 357 GLY   A CA  1 
ATOM   2637 C C   . GLY   A 1 332 ? 160.682 149.676 167.623 1.00 82.15  ? 357 GLY   A C   1 
ATOM   2638 O O   . GLY   A 1 332 ? 161.251 150.286 166.713 1.00 86.50  ? 357 GLY   A O   1 
ATOM   2639 N N   . LEU   A 1 333 ? 160.451 148.364 167.582 1.00 73.98  ? 358 LEU   A N   1 
ATOM   2640 C CA  . LEU   A 1 333 ? 160.886 147.514 166.482 1.00 76.25  ? 358 LEU   A CA  1 
ATOM   2641 C C   . LEU   A 1 333 ? 159.765 147.175 165.511 1.00 79.32  ? 358 LEU   A C   1 
ATOM   2642 O O   . LEU   A 1 333 ? 159.990 147.163 164.297 1.00 85.16  ? 358 LEU   A O   1 
ATOM   2643 C CB  . LEU   A 1 333 ? 161.488 146.217 167.032 1.00 80.53  ? 358 LEU   A CB  1 
ATOM   2644 C CG  . LEU   A 1 333 ? 162.088 145.223 166.032 1.00 85.88  ? 358 LEU   A CG  1 
ATOM   2645 C CD1 . LEU   A 1 333 ? 163.229 145.846 165.244 1.00 85.31  ? 358 LEU   A CD1 1 
ATOM   2646 C CD2 . LEU   A 1 333 ? 162.562 143.977 166.758 1.00 85.05  ? 358 LEU   A CD2 1 
ATOM   2647 N N   . ARG   A 1 334 ? 158.563 146.892 166.015 1.00 75.10  ? 359 ARG   A N   1 
ATOM   2648 C CA  . ARG   A 1 334 ? 157.474 146.484 165.134 1.00 74.93  ? 359 ARG   A CA  1 
ATOM   2649 C C   . ARG   A 1 334 ? 157.062 147.614 164.198 1.00 76.85  ? 359 ARG   A C   1 
ATOM   2650 O O   . ARG   A 1 334 ? 156.668 147.365 163.053 1.00 81.82  ? 359 ARG   A O   1 
ATOM   2651 C CB  . ARG   A 1 334 ? 156.285 145.995 165.960 1.00 78.69  ? 359 ARG   A CB  1 
ATOM   2652 C CG  . ARG   A 1 334 ? 155.660 147.033 166.873 1.00 86.63  ? 359 ARG   A CG  1 
ATOM   2653 C CD  . ARG   A 1 334 ? 154.654 146.392 167.818 1.00 91.12  ? 359 ARG   A CD  1 
ATOM   2654 N NE  . ARG   A 1 334 ? 153.599 145.677 167.108 1.00 94.83  ? 359 ARG   A NE  1 
ATOM   2655 C CZ  . ARG   A 1 334 ? 152.609 145.011 167.688 1.00 98.46  ? 359 ARG   A CZ  1 
ATOM   2656 N NH1 . ARG   A 1 334 ? 152.498 144.935 169.007 1.00 96.60  ? 359 ARG   A NH1 1 
ATOM   2657 N NH2 . ARG   A 1 334 ? 151.704 144.402 166.927 1.00 94.29  ? 359 ARG   A NH2 1 
ATOM   2658 N N   . HIS   A 1 335 ? 157.155 148.862 164.660 1.00 73.50  ? 360 HIS   A N   1 
ATOM   2659 C CA  . HIS   A 1 335 ? 156.793 149.995 163.812 1.00 76.12  ? 360 HIS   A CA  1 
ATOM   2660 C C   . HIS   A 1 335 ? 157.746 150.111 162.627 1.00 79.19  ? 360 HIS   A C   1 
ATOM   2661 O O   . HIS   A 1 335 ? 157.321 150.302 161.477 1.00 84.71  ? 360 HIS   A O   1 
ATOM   2662 C CB  . HIS   A 1 335 ? 156.805 151.286 164.634 1.00 79.21  ? 360 HIS   A CB  1 
ATOM   2663 C CG  . HIS   A 1 335 ? 156.013 151.206 165.903 1.00 78.18  ? 360 HIS   A CG  1 
ATOM   2664 N ND1 . HIS   A 1 335 ? 156.600 150.979 167.129 1.00 74.53  ? 360 HIS   A ND1 1 
ATOM   2665 C CD2 . HIS   A 1 335 ? 154.684 151.309 166.137 1.00 79.97  ? 360 HIS   A CD2 1 
ATOM   2666 C CE1 . HIS   A 1 335 ? 155.668 150.952 168.063 1.00 73.94  ? 360 HIS   A CE1 1 
ATOM   2667 N NE2 . HIS   A 1 335 ? 154.496 151.151 167.488 1.00 80.03  ? 360 HIS   A NE2 1 
ATOM   2668 N N   . GLN   A 1 336 ? 159.047 149.992 162.894 1.00 73.82  ? 361 GLN   A N   1 
ATOM   2669 C CA  . GLN   A 1 336 ? 160.036 150.081 161.829 1.00 74.40  ? 361 GLN   A CA  1 
ATOM   2670 C C   . GLN   A 1 336 ? 159.883 148.927 160.850 1.00 77.37  ? 361 GLN   A C   1 
ATOM   2671 O O   . GLN   A 1 336 ? 160.005 149.113 159.632 1.00 80.34  ? 361 GLN   A O   1 
ATOM   2672 C CB  . GLN   A 1 336 ? 161.441 150.101 162.427 1.00 77.09  ? 361 GLN   A CB  1 
ATOM   2673 C CG  . GLN   A 1 336 ? 161.695 151.262 163.373 1.00 80.88  ? 361 GLN   A CG  1 
ATOM   2674 C CD  . GLN   A 1 336 ? 163.059 151.194 164.019 1.00 85.85  ? 361 GLN   A CD  1 
ATOM   2675 O OE1 . GLN   A 1 336 ? 163.785 150.214 163.858 1.00 87.15  ? 361 GLN   A OE1 1 
ATOM   2676 N NE2 . GLN   A 1 336 ? 163.417 152.236 164.758 1.00 86.45  ? 361 GLN   A NE2 1 
ATOM   2677 N N   . LEU   A 1 337 ? 159.619 147.725 161.367 1.00 76.79  ? 362 LEU   A N   1 
ATOM   2678 C CA  . LEU   A 1 337 ? 159.395 146.581 160.493 1.00 75.25  ? 362 LEU   A CA  1 
ATOM   2679 C C   . LEU   A 1 337 ? 158.170 146.796 159.621 1.00 76.11  ? 362 LEU   A C   1 
ATOM   2680 O O   . LEU   A 1 337 ? 158.177 146.446 158.437 1.00 82.10  ? 362 LEU   A O   1 
ATOM   2681 C CB  . LEU   A 1 337 ? 159.242 145.306 161.320 1.00 75.09  ? 362 LEU   A CB  1 
ATOM   2682 C CG  . LEU   A 1 337 ? 160.487 144.777 162.034 1.00 78.91  ? 362 LEU   A CG  1 
ATOM   2683 C CD1 . LEU   A 1 337 ? 160.117 143.619 162.945 1.00 81.48  ? 362 LEU   A CD1 1 
ATOM   2684 C CD2 . LEU   A 1 337 ? 161.550 144.349 161.041 1.00 78.21  ? 362 LEU   A CD2 1 
ATOM   2685 N N   . GLY   A 1 338 ? 157.110 147.381 160.181 1.00 68.19  ? 363 GLY   A N   1 
ATOM   2686 C CA  . GLY   A 1 338 ? 155.933 147.667 159.379 1.00 70.69  ? 363 GLY   A CA  1 
ATOM   2687 C C   . GLY   A 1 338 ? 156.216 148.651 158.261 1.00 75.98  ? 363 GLY   A C   1 
ATOM   2688 O O   . GLY   A 1 338 ? 155.797 148.444 157.117 1.00 80.50  ? 363 GLY   A O   1 
ATOM   2689 N N   . ALA   A 1 339 ? 156.936 149.732 158.572 1.00 71.55  ? 364 ALA   A N   1 
ATOM   2690 C CA  . ALA   A 1 339 ? 157.253 150.723 157.547 1.00 73.85  ? 364 ALA   A CA  1 
ATOM   2691 C C   . ALA   A 1 339 ? 158.120 150.120 156.444 1.00 75.41  ? 364 ALA   A C   1 
ATOM   2692 O O   . ALA   A 1 339 ? 157.865 150.324 155.244 1.00 76.03  ? 364 ALA   A O   1 
ATOM   2693 C CB  . ALA   A 1 339 ? 157.954 151.921 158.183 1.00 74.87  ? 364 ALA   A CB  1 
ATOM   2694 N N   . ALA   A 1 340 ? 159.150 149.365 156.837 1.00 73.65  ? 365 ALA   A N   1 
ATOM   2695 C CA  . ALA   A 1 340 ? 160.023 148.735 155.855 1.00 70.93  ? 365 ALA   A CA  1 
ATOM   2696 C C   . ALA   A 1 340 ? 159.255 147.737 155.002 1.00 69.34  ? 365 ALA   A C   1 
ATOM   2697 O O   . ALA   A 1 340 ? 159.450 147.673 153.783 1.00 72.75  ? 365 ALA   A O   1 
ATOM   2698 C CB  . ALA   A 1 340 ? 161.194 148.051 156.557 1.00 70.64  ? 365 ALA   A CB  1 
ATOM   2699 N N   . PHE   A 1 341 ? 158.381 146.945 155.628 1.00 69.24  ? 366 PHE   A N   1 
ATOM   2700 C CA  . PHE   A 1 341 ? 157.578 145.988 154.883 1.00 68.58  ? 366 PHE   A CA  1 
ATOM   2701 C C   . PHE   A 1 341 ? 156.698 146.690 153.865 1.00 68.30  ? 366 PHE   A C   1 
ATOM   2702 O O   . PHE   A 1 341 ? 156.611 146.255 152.715 1.00 69.83  ? 366 PHE   A O   1 
ATOM   2703 C CB  . PHE   A 1 341 ? 156.724 145.162 155.844 1.00 70.00  ? 366 PHE   A CB  1 
ATOM   2704 C CG  . PHE   A 1 341 ? 155.647 144.364 155.168 1.00 71.41  ? 366 PHE   A CG  1 
ATOM   2705 C CD1 . PHE   A 1 341 ? 155.948 143.187 154.512 1.00 75.51  ? 366 PHE   A CD1 1 
ATOM   2706 C CD2 . PHE   A 1 341 ? 154.331 144.786 155.199 1.00 70.92  ? 366 PHE   A CD2 1 
ATOM   2707 C CE1 . PHE   A 1 341 ? 154.960 142.453 153.895 1.00 73.08  ? 366 PHE   A CE1 1 
ATOM   2708 C CE2 . PHE   A 1 341 ? 153.342 144.056 154.581 1.00 74.14  ? 366 PHE   A CE2 1 
ATOM   2709 C CZ  . PHE   A 1 341 ? 153.657 142.889 153.930 1.00 71.79  ? 366 PHE   A CZ  1 
ATOM   2710 N N   . THR   A 1 342 ? 156.050 147.787 154.265 1.00 66.96  ? 367 THR   A N   1 
ATOM   2711 C CA  . THR   A 1 342 ? 155.196 148.521 153.337 1.00 64.27  ? 367 THR   A CA  1 
ATOM   2712 C C   . THR   A 1 342 ? 155.985 149.005 152.128 1.00 66.66  ? 367 THR   A C   1 
ATOM   2713 O O   . THR   A 1 342 ? 155.614 148.731 150.976 1.00 70.69  ? 367 THR   A O   1 
ATOM   2714 C CB  . THR   A 1 342 ? 154.546 149.701 154.055 1.00 69.93  ? 367 THR   A CB  1 
ATOM   2715 O OG1 . THR   A 1 342 ? 153.733 149.217 155.129 1.00 74.85  ? 367 THR   A OG1 1 
ATOM   2716 C CG2 . THR   A 1 342 ? 153.691 150.512 153.098 1.00 68.73  ? 367 THR   A CG2 1 
ATOM   2717 N N   . LEU   A 1 343 ? 157.099 149.703 152.373 1.00 67.30  ? 368 LEU   A N   1 
ATOM   2718 C CA  . LEU   A 1 343 ? 157.862 150.271 151.265 1.00 62.91  ? 368 LEU   A CA  1 
ATOM   2719 C C   . LEU   A 1 343 ? 158.411 149.179 150.352 1.00 65.30  ? 368 LEU   A C   1 
ATOM   2720 O O   . LEU   A 1 343 ? 158.244 149.235 149.125 1.00 71.73  ? 368 LEU   A O   1 
ATOM   2721 C CB  . LEU   A 1 343 ? 158.998 151.145 151.799 1.00 64.04  ? 368 LEU   A CB  1 
ATOM   2722 C CG  . LEU   A 1 343 ? 158.600 152.395 152.586 1.00 73.61  ? 368 LEU   A CG  1 
ATOM   2723 C CD1 . LEU   A 1 343 ? 159.835 153.077 153.142 1.00 74.83  ? 368 LEU   A CD1 1 
ATOM   2724 C CD2 . LEU   A 1 343 ? 157.802 153.365 151.732 1.00 77.59  ? 368 LEU   A CD2 1 
ATOM   2725 N N   . LEU   A 1 344 ? 159.054 148.163 150.935 1.00 61.63  ? 369 LEU   A N   1 
ATOM   2726 C CA  . LEU   A 1 344 ? 159.658 147.111 150.126 1.00 57.51  ? 369 LEU   A CA  1 
ATOM   2727 C C   . LEU   A 1 344 ? 158.607 146.312 149.367 1.00 60.13  ? 369 LEU   A C   1 
ATOM   2728 O O   . LEU   A 1 344 ? 158.817 145.965 148.200 1.00 66.24  ? 369 LEU   A O   1 
ATOM   2729 C CB  . LEU   A 1 344 ? 160.500 146.189 151.006 1.00 60.87  ? 369 LEU   A CB  1 
ATOM   2730 C CG  . LEU   A 1 344 ? 161.962 146.595 151.218 1.00 63.43  ? 369 LEU   A CG  1 
ATOM   2731 C CD1 . LEU   A 1 344 ? 162.101 148.003 151.780 1.00 62.39  ? 369 LEU   A CD1 1 
ATOM   2732 C CD2 . LEU   A 1 344 ? 162.648 145.593 152.130 1.00 62.59  ? 369 LEU   A CD2 1 
ATOM   2733 N N   . TYR   A 1 345 ? 157.474 146.003 150.002 1.00 56.06  ? 370 TYR   A N   1 
ATOM   2734 C CA  . TYR   A 1 345 ? 156.440 145.229 149.329 1.00 56.48  ? 370 TYR   A CA  1 
ATOM   2735 C C   . TYR   A 1 345 ? 155.845 145.998 148.160 1.00 61.75  ? 370 TYR   A C   1 
ATOM   2736 O O   . TYR   A 1 345 ? 155.632 145.426 147.083 1.00 66.06  ? 370 TYR   A O   1 
ATOM   2737 C CB  . TYR   A 1 345 ? 155.351 144.845 150.327 1.00 59.41  ? 370 TYR   A CB  1 
ATOM   2738 C CG  . TYR   A 1 345 ? 154.223 144.044 149.728 1.00 61.49  ? 370 TYR   A CG  1 
ATOM   2739 C CD1 . TYR   A 1 345 ? 154.343 142.680 149.538 1.00 61.29  ? 370 TYR   A CD1 1 
ATOM   2740 C CD2 . TYR   A 1 345 ? 153.033 144.651 149.364 1.00 64.30  ? 370 TYR   A CD2 1 
ATOM   2741 C CE1 . TYR   A 1 345 ? 153.316 141.945 148.995 1.00 60.90  ? 370 TYR   A CE1 1 
ATOM   2742 C CE2 . TYR   A 1 345 ? 152.003 143.924 148.821 1.00 62.56  ? 370 TYR   A CE2 1 
ATOM   2743 C CZ  . TYR   A 1 345 ? 152.150 142.573 148.639 1.00 60.64  ? 370 TYR   A CZ  1 
ATOM   2744 O OH  . TYR   A 1 345 ? 151.117 141.848 148.097 1.00 64.23  ? 370 TYR   A OH  1 
ATOM   2745 N N   . LEU   A 1 346 ? 155.566 147.291 148.341 1.00 62.03  ? 371 LEU   A N   1 
ATOM   2746 C CA  . LEU   A 1 346 ? 155.017 148.063 147.232 1.00 59.76  ? 371 LEU   A CA  1 
ATOM   2747 C C   . LEU   A 1 346 ? 156.028 148.187 146.098 1.00 62.13  ? 371 LEU   A C   1 
ATOM   2748 O O   . LEU   A 1 346 ? 155.663 148.091 144.917 1.00 68.20  ? 371 LEU   A O   1 
ATOM   2749 C CB  . LEU   A 1 346 ? 154.568 149.440 147.721 1.00 64.24  ? 371 LEU   A CB  1 
ATOM   2750 C CG  . LEU   A 1 346 ? 153.393 149.454 148.706 1.00 65.87  ? 371 LEU   A CG  1 
ATOM   2751 C CD1 . LEU   A 1 346 ? 153.158 150.854 149.236 1.00 68.62  ? 371 LEU   A CD1 1 
ATOM   2752 C CD2 . LEU   A 1 346 ? 152.125 148.917 148.067 1.00 65.69  ? 371 LEU   A CD2 1 
ATOM   2753 N N   . LEU   A 1 347 ? 157.307 148.381 146.431 1.00 60.49  ? 372 LEU   A N   1 
ATOM   2754 C CA  . LEU   A 1 347 ? 158.326 148.456 145.387 1.00 60.88  ? 372 LEU   A CA  1 
ATOM   2755 C C   . LEU   A 1 347 ? 158.435 147.137 144.628 1.00 62.82  ? 372 LEU   A C   1 
ATOM   2756 O O   . LEU   A 1 347 ? 158.559 147.125 143.396 1.00 64.03  ? 372 LEU   A O   1 
ATOM   2757 C CB  . LEU   A 1 347 ? 159.672 148.839 146.001 1.00 60.88  ? 372 LEU   A CB  1 
ATOM   2758 C CG  . LEU   A 1 347 ? 160.579 149.745 145.171 1.00 67.39  ? 372 LEU   A CG  1 
ATOM   2759 C CD1 . LEU   A 1 347 ? 159.993 151.143 145.043 1.00 67.76  ? 372 LEU   A CD1 1 
ATOM   2760 C CD2 . LEU   A 1 347 ? 161.969 149.805 145.784 1.00 70.76  ? 372 LEU   A CD2 1 
ATOM   2761 N N   . GLU   A 1 348 ? 158.381 146.014 145.348 1.00 60.71  ? 373 GLU   A N   1 
ATOM   2762 C CA  . GLU   A 1 348 ? 158.437 144.709 144.698 1.00 58.91  ? 373 GLU   A CA  1 
ATOM   2763 C C   . GLU   A 1 348 ? 157.235 144.489 143.793 1.00 60.34  ? 373 GLU   A C   1 
ATOM   2764 O O   . GLU   A 1 348 ? 157.367 143.925 142.701 1.00 66.05  ? 373 GLU   A O   1 
ATOM   2765 C CB  . GLU   A 1 348 ? 158.522 143.607 145.754 1.00 62.77  ? 373 GLU   A CB  1 
ATOM   2766 C CG  . GLU   A 1 348 ? 158.516 142.188 145.193 1.00 66.32  ? 373 GLU   A CG  1 
ATOM   2767 C CD  . GLU   A 1 348 ? 157.146 141.529 145.197 1.00 74.33  ? 373 GLU   A CD  1 
ATOM   2768 O OE1 . GLU   A 1 348 ? 156.124 142.234 145.331 1.00 73.15  ? 373 GLU   A OE1 1 
ATOM   2769 O OE2 . GLU   A 1 348 ? 157.092 140.289 145.065 1.00 80.03  ? 373 GLU   A OE2 1 
ATOM   2770 N N   . GLN   A 1 349 ? 156.046 144.895 144.241 1.00 62.71  ? 374 GLN   A N   1 
ATOM   2771 C CA  . GLN   A 1 349 ? 154.860 144.736 143.406 1.00 60.60  ? 374 GLN   A CA  1 
ATOM   2772 C C   . GLN   A 1 349 ? 154.950 145.596 142.155 1.00 61.33  ? 374 GLN   A C   1 
ATOM   2773 O O   . GLN   A 1 349 ? 154.479 145.197 141.085 1.00 64.40  ? 374 GLN   A O   1 
ATOM   2774 C CB  . GLN   A 1 349 ? 153.599 145.075 144.199 1.00 61.27  ? 374 GLN   A CB  1 
ATOM   2775 C CG  . GLN   A 1 349 ? 153.118 143.959 145.107 1.00 63.32  ? 374 GLN   A CG  1 
ATOM   2776 C CD  . GLN   A 1 349 ? 152.602 142.764 144.339 1.00 64.68  ? 374 GLN   A CD  1 
ATOM   2777 O OE1 . GLN   A 1 349 ? 152.057 142.903 143.248 1.00 65.88  ? 374 GLN   A OE1 1 
ATOM   2778 N NE2 . GLN   A 1 349 ? 152.780 141.576 144.905 1.00 67.48  ? 374 GLN   A NE2 1 
ATOM   2779 N N   . LEU   A 1 350 ? 155.532 146.789 142.270 1.00 62.26  ? 375 LEU   A N   1 
ATOM   2780 C CA  . LEU   A 1 350 ? 155.753 147.602 141.079 1.00 59.95  ? 375 LEU   A CA  1 
ATOM   2781 C C   . LEU   A 1 350 ? 156.739 146.937 140.127 1.00 61.75  ? 375 LEU   A C   1 
ATOM   2782 O O   . LEU   A 1 350 ? 156.545 146.962 138.907 1.00 61.44  ? 375 LEU   A O   1 
ATOM   2783 C CB  . LEU   A 1 350 ? 156.251 148.993 141.473 1.00 59.82  ? 375 LEU   A CB  1 
ATOM   2784 C CG  . LEU   A 1 350 ? 155.202 149.999 141.947 1.00 64.64  ? 375 LEU   A CG  1 
ATOM   2785 C CD1 . LEU   A 1 350 ? 155.883 151.217 142.542 1.00 64.56  ? 375 LEU   A CD1 1 
ATOM   2786 C CD2 . LEU   A 1 350 ? 154.281 150.412 140.812 1.00 63.57  ? 375 LEU   A CD2 1 
ATOM   2787 N N   . PHE   A 1 351 ? 157.805 146.338 140.662 1.00 62.83  ? 376 PHE   A N   1 
ATOM   2788 C CA  . PHE   A 1 351 ? 158.861 145.813 139.800 1.00 56.69  ? 376 PHE   A CA  1 
ATOM   2789 C C   . PHE   A 1 351 ? 158.482 144.494 139.135 1.00 61.01  ? 376 PHE   A C   1 
ATOM   2790 O O   . PHE   A 1 351 ? 158.857 144.258 137.981 1.00 65.39  ? 376 PHE   A O   1 
ATOM   2791 C CB  . PHE   A 1 351 ? 160.149 145.628 140.596 1.00 57.77  ? 376 PHE   A CB  1 
ATOM   2792 C CG  . PHE   A 1 351 ? 161.186 144.817 139.878 1.00 60.49  ? 376 PHE   A CG  1 
ATOM   2793 C CD1 . PHE   A 1 351 ? 161.859 145.337 138.789 1.00 60.23  ? 376 PHE   A CD1 1 
ATOM   2794 C CD2 . PHE   A 1 351 ? 161.489 143.535 140.293 1.00 67.24  ? 376 PHE   A CD2 1 
ATOM   2795 C CE1 . PHE   A 1 351 ? 162.811 144.596 138.129 1.00 64.25  ? 376 PHE   A CE1 1 
ATOM   2796 C CE2 . PHE   A 1 351 ? 162.440 142.790 139.636 1.00 70.24  ? 376 PHE   A CE2 1 
ATOM   2797 C CZ  . PHE   A 1 351 ? 163.102 143.321 138.552 1.00 67.85  ? 376 PHE   A CZ  1 
ATOM   2798 N N   . LEU   A 1 352 ? 157.759 143.621 139.841 1.00 64.35  ? 377 LEU   A N   1 
ATOM   2799 C CA  . LEU   A 1 352 ? 157.596 142.245 139.371 1.00 58.80  ? 377 LEU   A CA  1 
ATOM   2800 C C   . LEU   A 1 352 ? 156.913 142.122 138.013 1.00 59.68  ? 377 LEU   A C   1 
ATOM   2801 O O   . LEU   A 1 352 ? 157.374 141.301 137.202 1.00 67.91  ? 377 LEU   A O   1 
ATOM   2802 C CB  . LEU   A 1 352 ? 156.836 141.414 140.414 1.00 61.21  ? 377 LEU   A CB  1 
ATOM   2803 C CG  . LEU   A 1 352 ? 157.430 140.032 140.704 1.00 64.46  ? 377 LEU   A CG  1 
ATOM   2804 C CD1 . LEU   A 1 352 ? 156.589 139.291 141.729 1.00 66.40  ? 377 LEU   A CD1 1 
ATOM   2805 C CD2 . LEU   A 1 352 ? 157.561 139.215 139.436 1.00 63.37  ? 377 LEU   A CD2 1 
ATOM   2806 N N   . PRO   A 1 353 ? 155.840 142.856 137.699 1.00 57.10  ? 378 PRO   A N   1 
ATOM   2807 C CA  . PRO   A 1 353 ? 155.233 142.715 136.365 1.00 57.72  ? 378 PRO   A CA  1 
ATOM   2808 C C   . PRO   A 1 353 ? 156.157 143.072 135.216 1.00 62.70  ? 378 PRO   A C   1 
ATOM   2809 O O   . PRO   A 1 353 ? 155.911 142.621 134.091 1.00 68.88  ? 378 PRO   A O   1 
ATOM   2810 C CB  . PRO   A 1 353 ? 154.034 143.667 136.426 1.00 60.86  ? 378 PRO   A CB  1 
ATOM   2811 C CG  . PRO   A 1 353 ? 153.690 143.738 137.852 1.00 63.35  ? 378 PRO   A CG  1 
ATOM   2812 C CD  . PRO   A 1 353 ? 154.983 143.650 138.595 1.00 63.31  ? 378 PRO   A CD  1 
ATOM   2813 N N   . TYR   A 1 354 ? 157.208 143.858 135.456 1.00 60.23  ? 379 TYR   A N   1 
ATOM   2814 C CA  . TYR   A 1 354 ? 158.163 144.250 134.426 1.00 52.60  ? 379 TYR   A CA  1 
ATOM   2815 C C   . TYR   A 1 354 ? 159.504 143.539 134.572 1.00 55.05  ? 379 TYR   A C   1 
ATOM   2816 O O   . TYR   A 1 354 ? 160.517 144.033 134.071 1.00 59.28  ? 379 TYR   A O   1 
ATOM   2817 C CB  . TYR   A 1 354 ? 158.364 145.763 134.452 1.00 55.01  ? 379 TYR   A CB  1 
ATOM   2818 C CG  . TYR   A 1 354 ? 157.106 146.540 134.173 1.00 57.57  ? 379 TYR   A CG  1 
ATOM   2819 C CD1 . TYR   A 1 354 ? 156.622 146.666 132.884 1.00 56.59  ? 379 TYR   A CD1 1 
ATOM   2820 C CD2 . TYR   A 1 354 ? 156.405 147.151 135.196 1.00 63.81  ? 379 TYR   A CD2 1 
ATOM   2821 C CE1 . TYR   A 1 354 ? 155.476 147.375 132.622 1.00 58.68  ? 379 TYR   A CE1 1 
ATOM   2822 C CE2 . TYR   A 1 354 ? 155.258 147.864 134.943 1.00 65.99  ? 379 TYR   A CE2 1 
ATOM   2823 C CZ  . TYR   A 1 354 ? 154.798 147.971 133.654 1.00 64.35  ? 379 TYR   A CZ  1 
ATOM   2824 O OH  . TYR   A 1 354 ? 153.655 148.681 133.390 1.00 68.43  ? 379 TYR   A OH  1 
ATOM   2825 N N   . SER   A 1 355 ? 159.530 142.381 135.235 1.00 55.99  ? 380 SER   A N   1 
ATOM   2826 C CA  . SER   A 1 355 ? 160.758 141.626 135.456 1.00 59.66  ? 380 SER   A CA  1 
ATOM   2827 C C   . SER   A 1 355 ? 160.988 140.562 134.396 1.00 68.42  ? 380 SER   A C   1 
ATOM   2828 O O   . SER   A 1 355 ? 161.647 139.551 134.673 1.00 72.83  ? 380 SER   A O   1 
ATOM   2829 C CB  . SER   A 1 355 ? 160.730 140.980 136.839 1.00 62.99  ? 380 SER   A CB  1 
ATOM   2830 O OG  . SER   A 1 355 ? 159.778 139.935 136.887 1.00 68.72  ? 380 SER   A OG  1 
ATOM   2831 N N   . HIS   A 1 356 ? 160.465 140.758 133.187 1.00 67.94  ? 381 HIS   A N   1 
ATOM   2832 C CA  . HIS   A 1 356 ? 160.556 139.751 132.139 1.00 63.40  ? 381 HIS   A CA  1 
ATOM   2833 C C   . HIS   A 1 356 ? 161.875 139.786 131.381 1.00 62.95  ? 381 HIS   A C   1 
ATOM   2834 O O   . HIS   A 1 356 ? 162.106 138.905 130.547 1.00 67.41  ? 381 HIS   A O   1 
ATOM   2835 C CB  . HIS   A 1 356 ? 159.394 139.921 131.162 1.00 61.73  ? 381 HIS   A CB  1 
ATOM   2836 C CG  . HIS   A 1 356 ? 158.050 139.802 131.805 1.00 62.61  ? 381 HIS   A CG  1 
ATOM   2837 N ND1 . HIS   A 1 356 ? 157.656 138.677 132.493 1.00 66.65  ? 381 HIS   A ND1 1 
ATOM   2838 C CD2 . HIS   A 1 356 ? 157.009 140.664 131.866 1.00 66.57  ? 381 HIS   A CD2 1 
ATOM   2839 C CE1 . HIS   A 1 356 ? 156.430 138.850 132.952 1.00 71.41  ? 381 HIS   A CE1 1 
ATOM   2840 N NE2 . HIS   A 1 356 ? 156.015 140.049 132.585 1.00 69.29  ? 381 HIS   A NE2 1 
ATOM   2841 N N   . PHE   A 1 357 ? 162.744 140.760 131.649 1.00 60.36  ? 382 PHE   A N   1 
ATOM   2842 C CA  . PHE   A 1 357 ? 164.063 140.783 131.031 1.00 61.06  ? 382 PHE   A CA  1 
ATOM   2843 C C   . PHE   A 1 357 ? 165.083 139.932 131.777 1.00 67.43  ? 382 PHE   A C   1 
ATOM   2844 O O   . PHE   A 1 357 ? 166.199 139.760 131.275 1.00 70.37  ? 382 PHE   A O   1 
ATOM   2845 C CB  . PHE   A 1 357 ? 164.578 142.223 130.912 1.00 63.32  ? 382 PHE   A CB  1 
ATOM   2846 C CG  . PHE   A 1 357 ? 164.788 142.924 132.229 1.00 64.77  ? 382 PHE   A CG  1 
ATOM   2847 C CD1 . PHE   A 1 357 ? 163.776 143.676 132.799 1.00 67.69  ? 382 PHE   A CD1 1 
ATOM   2848 C CD2 . PHE   A 1 357 ? 166.008 142.863 132.877 1.00 65.43  ? 382 PHE   A CD2 1 
ATOM   2849 C CE1 . PHE   A 1 357 ? 163.969 144.327 133.997 1.00 67.27  ? 382 PHE   A CE1 1 
ATOM   2850 C CE2 . PHE   A 1 357 ? 166.205 143.510 134.075 1.00 65.38  ? 382 PHE   A CE2 1 
ATOM   2851 C CZ  . PHE   A 1 357 ? 165.186 144.245 134.634 1.00 65.66  ? 382 PHE   A CZ  1 
ATOM   2852 N N   . LEU   A 1 358 ? 164.736 139.400 132.949 1.00 66.94  ? 383 LEU   A N   1 
ATOM   2853 C CA  . LEU   A 1 358 ? 165.607 138.512 133.710 1.00 66.21  ? 383 LEU   A CA  1 
ATOM   2854 C C   . LEU   A 1 358 ? 165.281 137.046 133.467 1.00 66.90  ? 383 LEU   A C   1 
ATOM   2855 O O   . LEU   A 1 358 ? 166.185 136.240 133.231 1.00 70.63  ? 383 LEU   A O   1 
ATOM   2856 C CB  . LEU   A 1 358 ? 165.498 138.826 135.207 1.00 68.06  ? 383 LEU   A CB  1 
ATOM   2857 C CG  . LEU   A 1 358 ? 165.845 140.252 135.640 1.00 69.52  ? 383 LEU   A CG  1 
ATOM   2858 C CD1 . LEU   A 1 358 ? 165.542 140.442 137.112 1.00 66.40  ? 383 LEU   A CD1 1 
ATOM   2859 C CD2 . LEU   A 1 358 ? 167.302 140.571 135.353 1.00 68.87  ? 383 LEU   A CD2 1 
ATOM   2860 N N   . THR   A 1 359 ? 163.998 136.687 133.517 1.00 66.79  ? 384 THR   A N   1 
ATOM   2861 C CA  . THR   A 1 359 ? 163.548 135.321 133.265 1.00 73.43  ? 384 THR   A CA  1 
ATOM   2862 C C   . THR   A 1 359 ? 163.110 135.231 131.806 1.00 73.21  ? 384 THR   A C   1 
ATOM   2863 O O   . THR   A 1 359 ? 161.924 135.208 131.480 1.00 74.98  ? 384 THR   A O   1 
ATOM   2864 C CB  . THR   A 1 359 ? 162.419 134.946 134.218 1.00 74.14  ? 384 THR   A CB  1 
ATOM   2865 O OG1 . THR   A 1 359 ? 161.337 135.872 134.068 1.00 70.62  ? 384 THR   A OG1 1 
ATOM   2866 C CG2 . THR   A 1 359 ? 162.906 134.968 135.657 1.00 73.04  ? 384 THR   A CG2 1 
ATOM   2867 N N   . GLN   A 1 360 ? 164.101 135.181 130.916 1.00 66.64  ? 385 GLN   A N   1 
ATOM   2868 C CA  . GLN   A 1 360 ? 163.836 135.113 129.486 1.00 64.81  ? 385 GLN   A CA  1 
ATOM   2869 C C   . GLN   A 1 360 ? 163.518 133.706 129.000 1.00 66.60  ? 385 GLN   A C   1 
ATOM   2870 O O   . GLN   A 1 360 ? 163.037 133.558 127.873 1.00 72.08  ? 385 GLN   A O   1 
ATOM   2871 C CB  . GLN   A 1 360 ? 165.030 135.658 128.706 1.00 67.42  ? 385 GLN   A CB  1 
ATOM   2872 C CG  . GLN   A 1 360 ? 165.042 137.163 128.592 1.00 68.90  ? 385 GLN   A CG  1 
ATOM   2873 C CD  . GLN   A 1 360 ? 166.294 137.683 127.935 1.00 76.34  ? 385 GLN   A CD  1 
ATOM   2874 O OE1 . GLN   A 1 360 ? 167.396 137.213 128.214 1.00 81.00  ? 385 GLN   A OE1 1 
ATOM   2875 N NE2 . GLN   A 1 360 ? 166.136 138.659 127.051 1.00 77.14  ? 385 GLN   A NE2 1 
ATOM   2876 N N   . GLY   A 1 361 ? 163.773 132.677 129.807 1.00 66.58  ? 386 GLY   A N   1 
ATOM   2877 C CA  . GLY   A 1 361 ? 163.394 131.335 129.410 1.00 65.37  ? 386 GLY   A CA  1 
ATOM   2878 C C   . GLY   A 1 361 ? 161.898 131.170 129.259 1.00 65.93  ? 386 GLY   A C   1 
ATOM   2879 O O   . GLY   A 1 361 ? 161.436 130.430 128.388 1.00 72.28  ? 386 GLY   A O   1 
ATOM   2880 N N   . TYR   A 1 362 ? 161.123 131.850 130.100 1.00 65.33  ? 387 TYR   A N   1 
ATOM   2881 C CA  . TYR   A 1 362 ? 159.671 131.788 130.043 1.00 63.99  ? 387 TYR   A CA  1 
ATOM   2882 C C   . TYR   A 1 362 ? 159.074 132.735 129.013 1.00 63.81  ? 387 TYR   A C   1 
ATOM   2883 O O   . TYR   A 1 362 ? 157.858 132.704 128.806 1.00 65.24  ? 387 TYR   A O   1 
ATOM   2884 C CB  . TYR   A 1 362 ? 159.085 132.095 131.424 1.00 66.03  ? 387 TYR   A CB  1 
ATOM   2885 C CG  . TYR   A 1 362 ? 159.497 131.109 132.494 1.00 65.53  ? 387 TYR   A CG  1 
ATOM   2886 C CD1 . TYR   A 1 362 ? 158.768 129.954 132.717 1.00 66.29  ? 387 TYR   A CD1 1 
ATOM   2887 C CD2 . TYR   A 1 362 ? 160.616 131.331 133.274 1.00 64.18  ? 387 TYR   A CD2 1 
ATOM   2888 C CE1 . TYR   A 1 362 ? 159.141 129.053 133.686 1.00 64.90  ? 387 TYR   A CE1 1 
ATOM   2889 C CE2 . TYR   A 1 362 ? 160.996 130.436 134.246 1.00 67.11  ? 387 TYR   A CE2 1 
ATOM   2890 C CZ  . TYR   A 1 362 ? 160.255 129.298 134.448 1.00 68.26  ? 387 TYR   A CZ  1 
ATOM   2891 O OH  . TYR   A 1 362 ? 160.631 128.400 135.418 1.00 75.75  ? 387 TYR   A OH  1 
ATOM   2892 N N   . ASN   A 1 363 ? 159.882 133.570 128.366 1.00 66.75  ? 388 ASN   A N   1 
ATOM   2893 C CA  . ASN   A 1 363 ? 159.362 134.467 127.346 1.00 66.82  ? 388 ASN   A CA  1 
ATOM   2894 C C   . ASN   A 1 363 ? 158.956 133.695 126.097 1.00 67.88  ? 388 ASN   A C   1 
ATOM   2895 O O   . ASN   A 1 363 ? 159.523 132.652 125.763 1.00 70.13  ? 388 ASN   A O   1 
ATOM   2896 C CB  . ASN   A 1 363 ? 160.397 135.532 126.980 1.00 69.74  ? 388 ASN   A CB  1 
ATOM   2897 C CG  . ASN   A 1 363 ? 160.479 136.651 128.002 1.00 74.13  ? 388 ASN   A CG  1 
ATOM   2898 O OD1 . ASN   A 1 363 ? 159.584 136.828 128.827 1.00 76.45  ? 388 ASN   A OD1 1 
ATOM   2899 N ND2 . ASN   A 1 363 ? 161.557 137.422 127.943 1.00 75.28  ? 388 ASN   A ND2 1 
ATOM   2900 N N   . ASN   A 1 364 ? 157.960 134.233 125.407 1.00 67.86  ? 389 ASN   A N   1 
ATOM   2901 C CA  . ASN   A 1 364 ? 157.350 133.632 124.229 1.00 63.92  ? 389 ASN   A CA  1 
ATOM   2902 C C   . ASN   A 1 364 ? 156.899 134.784 123.336 1.00 69.28  ? 389 ASN   A C   1 
ATOM   2903 O O   . ASN   A 1 364 ? 157.439 135.892 123.424 1.00 77.00  ? 389 ASN   A O   1 
ATOM   2904 C CB  . ASN   A 1 364 ? 156.208 132.682 124.633 1.00 61.87  ? 389 ASN   A CB  1 
ATOM   2905 C CG  . ASN   A 1 364 ? 156.694 131.496 125.432 1.00 67.40  ? 389 ASN   A CG  1 
ATOM   2906 O OD1 . ASN   A 1 364 ? 157.659 130.835 125.054 1.00 73.04  ? 389 ASN   A OD1 1 
ATOM   2907 N ND2 . ASN   A 1 364 ? 156.034 131.224 126.551 1.00 71.88  ? 389 ASN   A ND2 1 
ATOM   2908 N N   . TRP   A 1 365 ? 155.958 134.511 122.430 1.00 61.71  ? 390 TRP   A N   1 
ATOM   2909 C CA  . TRP   A 1 365 ? 155.326 135.585 121.669 1.00 65.76  ? 390 TRP   A CA  1 
ATOM   2910 C C   . TRP   A 1 365 ? 154.798 136.679 122.592 1.00 72.70  ? 390 TRP   A C   1 
ATOM   2911 O O   . TRP   A 1 365 ? 154.919 137.870 122.283 1.00 78.11  ? 390 TRP   A O   1 
ATOM   2912 C CB  . TRP   A 1 365 ? 154.199 135.019 120.803 1.00 68.17  ? 390 TRP   A CB  1 
ATOM   2913 C CG  . TRP   A 1 365 ? 154.660 134.090 119.706 1.00 66.56  ? 390 TRP   A CG  1 
ATOM   2914 C CD1 . TRP   A 1 365 ? 155.943 133.721 119.419 1.00 65.05  ? 390 TRP   A CD1 1 
ATOM   2915 C CD2 . TRP   A 1 365 ? 153.832 133.415 118.755 1.00 60.07  ? 390 TRP   A CD2 1 
ATOM   2916 N NE1 . TRP   A 1 365 ? 155.962 132.861 118.354 1.00 66.56  ? 390 TRP   A NE1 1 
ATOM   2917 C CE2 . TRP   A 1 365 ? 154.677 132.658 117.927 1.00 61.42  ? 390 TRP   A CE2 1 
ATOM   2918 C CE3 . TRP   A 1 365 ? 152.456 133.379 118.524 1.00 60.50  ? 390 TRP   A CE3 1 
ATOM   2919 C CZ2 . TRP   A 1 365 ? 154.194 131.874 116.890 1.00 63.92  ? 390 TRP   A CZ2 1 
ATOM   2920 C CZ3 . TRP   A 1 365 ? 151.979 132.603 117.494 1.00 61.35  ? 390 TRP   A CZ3 1 
ATOM   2921 C CH2 . TRP   A 1 365 ? 152.844 131.861 116.688 1.00 64.49  ? 390 TRP   A CH2 1 
ATOM   2922 N N   . THR   A 1 366 ? 154.207 136.296 123.724 1.00 69.65  ? 391 THR   A N   1 
ATOM   2923 C CA  . THR   A 1 366 ? 153.897 137.213 124.809 1.00 68.73  ? 391 THR   A CA  1 
ATOM   2924 C C   . THR   A 1 366 ? 155.033 137.165 125.833 1.00 76.14  ? 391 THR   A C   1 
ATOM   2925 O O   . THR   A 1 366 ? 156.061 136.518 125.617 1.00 80.39  ? 391 THR   A O   1 
ATOM   2926 C CB  . THR   A 1 366 ? 152.544 136.866 125.434 1.00 70.83  ? 391 THR   A CB  1 
ATOM   2927 O OG1 . THR   A 1 366 ? 152.088 137.966 126.230 1.00 72.78  ? 391 THR   A OG1 1 
ATOM   2928 C CG2 . THR   A 1 366 ? 152.644 135.624 126.313 1.00 74.88  ? 391 THR   A CG2 1 
ATOM   2929 N N   . ASN   A 1 367 ? 154.848 137.839 126.966 1.00 77.22  ? 392 ASN   A N   1 
ATOM   2930 C CA  . ASN   A 1 367 ? 155.880 137.973 127.990 1.00 72.36  ? 392 ASN   A CA  1 
ATOM   2931 C C   . ASN   A 1 367 ? 155.532 137.114 129.198 1.00 71.38  ? 392 ASN   A C   1 
ATOM   2932 O O   . ASN   A 1 367 ? 154.462 137.277 129.793 1.00 74.07  ? 392 ASN   A O   1 
ATOM   2933 C CB  . ASN   A 1 367 ? 156.040 139.433 128.410 1.00 75.31  ? 392 ASN   A CB  1 
ATOM   2934 C CG  . ASN   A 1 367 ? 156.749 140.267 127.365 1.00 82.01  ? 392 ASN   A CG  1 
ATOM   2935 O OD1 . ASN   A 1 367 ? 157.574 139.763 126.604 1.00 77.80  ? 392 ASN   A OD1 1 
ATOM   2936 N ND2 . ASN   A 1 367 ? 156.434 141.556 127.326 1.00 85.56  ? 392 ASN   A ND2 1 
ATOM   2937 N N   . GLY   A 1 368 ? 156.437 136.205 129.551 1.00 71.34  ? 393 GLY   A N   1 
ATOM   2938 C CA  . GLY   A 1 368 ? 156.379 135.484 130.808 1.00 71.04  ? 393 GLY   A CA  1 
ATOM   2939 C C   . GLY   A 1 368 ? 155.187 134.571 130.989 1.00 69.87  ? 393 GLY   A C   1 
ATOM   2940 O O   . GLY   A 1 368 ? 154.260 134.569 130.176 1.00 71.58  ? 393 GLY   A O   1 
ATOM   2941 N N   . LEU   A 1 369 ? 155.205 133.789 132.066 1.00 68.01  ? 394 LEU   A N   1 
ATOM   2942 C CA  . LEU   A 1 369 ? 154.060 132.963 132.415 1.00 63.73  ? 394 LEU   A CA  1 
ATOM   2943 C C   . LEU   A 1 369 ? 152.873 133.844 132.770 1.00 64.79  ? 394 LEU   A C   1 
ATOM   2944 O O   . LEU   A 1 369 ? 153.022 134.943 133.310 1.00 71.39  ? 394 LEU   A O   1 
ATOM   2945 C CB  . LEU   A 1 369 ? 154.394 132.051 133.594 1.00 62.98  ? 394 LEU   A CB  1 
ATOM   2946 C CG  . LEU   A 1 369 ? 155.450 130.972 133.365 1.00 66.93  ? 394 LEU   A CG  1 
ATOM   2947 C CD1 . LEU   A 1 369 ? 155.859 130.359 134.689 1.00 67.47  ? 394 LEU   A CD1 1 
ATOM   2948 C CD2 . LEU   A 1 369 ? 154.932 129.903 132.422 1.00 67.67  ? 394 LEU   A CD2 1 
ATOM   2949 N N   . TYR   A 1 370 ? 151.681 133.353 132.461 1.00 53.77  ? 395 TYR   A N   1 
ATOM   2950 C CA  . TYR   A 1 370 ? 150.469 134.111 132.716 1.00 57.03  ? 395 TYR   A CA  1 
ATOM   2951 C C   . TYR   A 1 370 ? 150.113 134.066 134.194 1.00 66.40  ? 395 TYR   A C   1 
ATOM   2952 O O   . TYR   A 1 370 ? 150.236 133.023 134.842 1.00 68.27  ? 395 TYR   A O   1 
ATOM   2953 C CB  . TYR   A 1 370 ? 149.318 133.556 131.882 1.00 56.39  ? 395 TYR   A CB  1 
ATOM   2954 C CG  . TYR   A 1 370 ? 148.084 134.416 131.896 1.00 57.08  ? 395 TYR   A CG  1 
ATOM   2955 C CD1 . TYR   A 1 370 ? 147.961 135.494 131.041 1.00 63.88  ? 395 TYR   A CD1 1 
ATOM   2956 C CD2 . TYR   A 1 370 ? 147.039 134.142 132.754 1.00 60.36  ? 395 TYR   A CD2 1 
ATOM   2957 C CE1 . TYR   A 1 370 ? 146.837 136.278 131.048 1.00 69.23  ? 395 TYR   A CE1 1 
ATOM   2958 C CE2 . TYR   A 1 370 ? 145.914 134.919 132.769 1.00 64.65  ? 395 TYR   A CE2 1 
ATOM   2959 C CZ  . TYR   A 1 370 ? 145.814 135.987 131.915 1.00 69.07  ? 395 TYR   A CZ  1 
ATOM   2960 O OH  . TYR   A 1 370 ? 144.683 136.767 131.927 1.00 76.18  ? 395 TYR   A OH  1 
ATOM   2961 N N   . GLY   A 1 371 ? 149.672 135.208 134.723 1.00 65.28  ? 396 GLY   A N   1 
ATOM   2962 C CA  . GLY   A 1 371 ? 149.163 135.284 136.079 1.00 56.99  ? 396 GLY   A CA  1 
ATOM   2963 C C   . GLY   A 1 371 ? 149.615 136.478 136.896 1.00 60.28  ? 396 GLY   A C   1 
ATOM   2964 O O   . GLY   A 1 371 ? 148.858 136.945 137.752 1.00 66.90  ? 396 GLY   A O   1 
ATOM   2965 N N   . TYR   A 1 372 ? 150.826 136.985 136.654 1.00 58.84  ? 397 TYR   A N   1 
ATOM   2966 C CA  . TYR   A 1 372 ? 151.428 138.023 137.487 1.00 57.35  ? 397 TYR   A CA  1 
ATOM   2967 C C   . TYR   A 1 372 ? 151.814 139.263 136.686 1.00 60.30  ? 397 TYR   A C   1 
ATOM   2968 O O   . TYR   A 1 372 ? 152.725 139.994 137.074 1.00 67.08  ? 397 TYR   A O   1 
ATOM   2969 C CB  . TYR   A 1 372 ? 152.642 137.469 138.232 1.00 61.87  ? 397 TYR   A CB  1 
ATOM   2970 C CG  . TYR   A 1 372 ? 153.804 137.070 137.354 1.00 61.51  ? 397 TYR   A CG  1 
ATOM   2971 C CD1 . TYR   A 1 372 ? 153.821 135.851 136.701 1.00 62.36  ? 397 TYR   A CD1 1 
ATOM   2972 C CD2 . TYR   A 1 372 ? 154.899 137.903 137.205 1.00 64.84  ? 397 TYR   A CD2 1 
ATOM   2973 C CE1 . TYR   A 1 372 ? 154.887 135.486 135.909 1.00 65.52  ? 397 TYR   A CE1 1 
ATOM   2974 C CE2 . TYR   A 1 372 ? 155.964 137.545 136.416 1.00 65.93  ? 397 TYR   A CE2 1 
ATOM   2975 C CZ  . TYR   A 1 372 ? 155.957 136.337 135.773 1.00 67.35  ? 397 TYR   A CZ  1 
ATOM   2976 O OH  . TYR   A 1 372 ? 157.026 135.980 134.985 1.00 68.93  ? 397 TYR   A OH  1 
ATOM   2977 N N   . SER   A 1 373 ? 151.115 139.519 135.576 1.00 61.58  ? 398 SER   A N   1 
ATOM   2978 C CA  . SER   A 1 373 ? 151.355 140.685 134.735 1.00 61.58  ? 398 SER   A CA  1 
ATOM   2979 C C   . SER   A 1 373 ? 150.170 141.636 134.653 1.00 63.98  ? 398 SER   A C   1 
ATOM   2980 O O   . SER   A 1 373 ? 150.338 142.754 134.156 1.00 67.80  ? 398 SER   A O   1 
ATOM   2981 C CB  . SER   A 1 373 ? 151.732 140.242 133.315 1.00 68.32  ? 398 SER   A CB  1 
ATOM   2982 O OG  . SER   A 1 373 ? 152.838 139.359 133.339 1.00 73.04  ? 398 SER   A OG  1 
ATOM   2983 N N   . TRP   A 1 374 ? 148.987 141.228 135.108 1.00 64.25  ? 399 TRP   A N   1 
ATOM   2984 C CA  . TRP   A 1 374 ? 147.768 142.032 135.048 1.00 65.77  ? 399 TRP   A CA  1 
ATOM   2985 C C   . TRP   A 1 374 ? 147.345 142.343 133.615 1.00 71.32  ? 399 TRP   A C   1 
ATOM   2986 O O   . TRP   A 1 374 ? 146.627 143.321 133.381 1.00 74.89  ? 399 TRP   A O   1 
ATOM   2987 C CB  . TRP   A 1 374 ? 147.913 143.337 135.841 1.00 61.55  ? 399 TRP   A CB  1 
ATOM   2988 C CG  . TRP   A 1 374 ? 148.477 143.163 137.219 1.00 61.14  ? 399 TRP   A CG  1 
ATOM   2989 C CD1 . TRP   A 1 374 ? 149.645 143.675 137.693 1.00 64.65  ? 399 TRP   A CD1 1 
ATOM   2990 C CD2 . TRP   A 1 374 ? 147.897 142.424 138.300 1.00 61.77  ? 399 TRP   A CD2 1 
ATOM   2991 N NE1 . TRP   A 1 374 ? 149.831 143.304 138.999 1.00 62.05  ? 399 TRP   A NE1 1 
ATOM   2992 C CE2 . TRP   A 1 374 ? 148.771 142.534 139.395 1.00 56.57  ? 399 TRP   A CE2 1 
ATOM   2993 C CE3 . TRP   A 1 374 ? 146.724 141.679 138.446 1.00 66.21  ? 399 TRP   A CE3 1 
ATOM   2994 C CZ2 . TRP   A 1 374 ? 148.513 141.929 140.617 1.00 61.07  ? 399 TRP   A CZ2 1 
ATOM   2995 C CZ3 . TRP   A 1 374 ? 146.470 141.080 139.662 1.00 62.90  ? 399 TRP   A CZ3 1 
ATOM   2996 C CH2 . TRP   A 1 374 ? 147.359 141.207 140.730 1.00 61.16  ? 399 TRP   A CH2 1 
ATOM   2997 N N   . ASP   A 1 375 ? 147.766 141.525 132.646 1.00 69.08  ? 400 ASP   A N   1 
ATOM   2998 C CA  . ASP   A 1 375 ? 147.368 141.698 131.246 1.00 65.65  ? 400 ASP   A CA  1 
ATOM   2999 C C   . ASP   A 1 375 ? 146.134 140.836 130.995 1.00 63.74  ? 400 ASP   A C   1 
ATOM   3000 O O   . ASP   A 1 375 ? 146.186 139.750 130.416 1.00 66.29  ? 400 ASP   A O   1 
ATOM   3001 C CB  . ASP   A 1 375 ? 148.519 141.357 130.303 1.00 69.71  ? 400 ASP   A CB  1 
ATOM   3002 C CG  . ASP   A 1 375 ? 149.072 139.964 130.521 1.00 73.42  ? 400 ASP   A CG  1 
ATOM   3003 O OD1 . ASP   A 1 375 ? 148.829 139.394 131.604 1.00 69.28  ? 400 ASP   A OD1 1 
ATOM   3004 O OD2 . ASP   A 1 375 ? 149.750 139.444 129.611 1.00 75.06  ? 400 ASP   A OD2 1 
ATOM   3005 N N   . MET   A 1 376 ? 144.993 141.355 131.436 1.00 61.94  ? 401 MET   A N   1 
ATOM   3006 C CA  . MET   A 1 376 ? 143.734 140.629 131.381 1.00 63.37  ? 401 MET   A CA  1 
ATOM   3007 C C   . MET   A 1 376 ? 143.036 140.895 130.055 1.00 65.03  ? 401 MET   A C   1 
ATOM   3008 O O   . MET   A 1 376 ? 142.813 142.052 129.685 1.00 70.20  ? 401 MET   A O   1 
ATOM   3009 C CB  . MET   A 1 376 ? 142.828 141.045 132.540 1.00 70.40  ? 401 MET   A CB  1 
ATOM   3010 C CG  . MET   A 1 376 ? 143.424 140.829 133.923 1.00 71.76  ? 401 MET   A CG  1 
ATOM   3011 S SD  . MET   A 1 376 ? 142.435 141.609 135.209 1.00 90.31  ? 401 MET   A SD  1 
ATOM   3012 C CE  . MET   A 1 376 ? 143.549 141.505 136.605 1.00 74.59  ? 401 MET   A CE  1 
ATOM   3013 N N   . MET   A 1 377 ? 142.682 139.819 129.353 1.00 62.81  ? 402 MET   A N   1 
ATOM   3014 C CA  . MET   A 1 377 ? 141.873 139.888 128.137 1.00 63.95  ? 402 MET   A CA  1 
ATOM   3015 C C   . MET   A 1 377 ? 142.536 140.759 127.069 1.00 64.97  ? 402 MET   A C   1 
ATOM   3016 O O   . MET   A 1 377 ? 141.885 141.572 126.412 1.00 70.68  ? 402 MET   A O   1 
ATOM   3017 C CB  . MET   A 1 377 ? 140.466 140.405 128.447 1.00 66.75  ? 402 MET   A CB  1 
ATOM   3018 C CG  . MET   A 1 377 ? 139.861 139.940 129.764 1.00 71.27  ? 402 MET   A CG  1 
ATOM   3019 S SD  . MET   A 1 377 ? 139.839 138.159 129.985 1.00 81.96  ? 402 MET   A SD  1 
ATOM   3020 C CE  . MET   A 1 377 ? 138.785 138.028 131.423 1.00 73.28  ? 402 MET   A CE  1 
ATOM   3021 N N   . VAL   A 1 378 ? 143.842 140.569 126.886 1.00 57.54  ? 403 VAL   A N   1 
ATOM   3022 C CA  . VAL   A 1 378 ? 144.624 141.352 125.934 1.00 58.48  ? 403 VAL   A CA  1 
ATOM   3023 C C   . VAL   A 1 378 ? 145.161 140.517 124.783 1.00 63.42  ? 403 VAL   A C   1 
ATOM   3024 O O   . VAL   A 1 378 ? 145.567 141.092 123.762 1.00 72.01  ? 403 VAL   A O   1 
ATOM   3025 C CB  . VAL   A 1 378 ? 145.788 142.086 126.638 1.00 62.91  ? 403 VAL   A CB  1 
ATOM   3026 C CG1 . VAL   A 1 378 ? 146.410 143.138 125.724 1.00 64.70  ? 403 VAL   A CG1 1 
ATOM   3027 C CG2 . VAL   A 1 378 ? 145.306 142.715 127.944 1.00 68.24  ? 403 VAL   A CG2 1 
ATOM   3028 N N   . HIS   A 1 379 ? 145.163 139.189 124.893 1.00 62.61  ? 404 HIS   A N   1 
ATOM   3029 C CA  . HIS   A 1 379 ? 145.564 138.310 123.805 1.00 59.06  ? 404 HIS   A CA  1 
ATOM   3030 C C   . HIS   A 1 379 ? 144.616 137.123 123.744 1.00 63.38  ? 404 HIS   A C   1 
ATOM   3031 O O   . HIS   A 1 379 ? 144.310 136.510 124.769 1.00 70.53  ? 404 HIS   A O   1 
ATOM   3032 C CB  . HIS   A 1 379 ? 147.001 137.812 123.984 1.00 59.59  ? 404 HIS   A CB  1 
ATOM   3033 C CG  . HIS   A 1 379 ? 148.022 138.905 124.021 1.00 63.54  ? 404 HIS   A CG  1 
ATOM   3034 N ND1 . HIS   A 1 379 ? 148.283 139.717 122.939 1.00 71.21  ? 404 HIS   A ND1 1 
ATOM   3035 C CD2 . HIS   A 1 379 ? 148.858 139.309 125.005 1.00 63.56  ? 404 HIS   A CD2 1 
ATOM   3036 C CE1 . HIS   A 1 379 ? 149.229 140.580 123.258 1.00 68.01  ? 404 HIS   A CE1 1 
ATOM   3037 N NE2 . HIS   A 1 379 ? 149.596 140.354 124.506 1.00 69.18  ? 404 HIS   A NE2 1 
ATOM   3038 N N   . SER   A 1 380 ? 144.154 136.810 122.537 1.00 61.54  ? 405 SER   A N   1 
ATOM   3039 C CA  . SER   A 1 380 ? 143.317 135.650 122.268 1.00 62.95  ? 405 SER   A CA  1 
ATOM   3040 C C   . SER   A 1 380 ? 143.999 134.794 121.214 1.00 64.87  ? 405 SER   A C   1 
ATOM   3041 O O   . SER   A 1 380 ? 144.562 135.322 120.253 1.00 68.65  ? 405 SER   A O   1 
ATOM   3042 C CB  . SER   A 1 380 ? 141.929 136.068 121.784 1.00 65.86  ? 405 SER   A CB  1 
ATOM   3043 O OG  . SER   A 1 380 ? 141.285 136.891 122.739 1.00 72.43  ? 405 SER   A OG  1 
ATOM   3044 N N   . ARG   A 1 381 ? 143.930 133.475 121.388 1.00 61.70  ? 406 ARG   A N   1 
ATOM   3045 C CA  . ARG   A 1 381 ? 144.676 132.527 120.573 1.00 60.32  ? 406 ARG   A CA  1 
ATOM   3046 C C   . ARG   A 1 381 ? 143.730 131.516 119.948 1.00 61.93  ? 406 ARG   A C   1 
ATOM   3047 O O   . ARG   A 1 381 ? 142.765 131.083 120.585 1.00 67.08  ? 406 ARG   A O   1 
ATOM   3048 C CB  . ARG   A 1 381 ? 145.730 131.801 121.406 1.00 61.31  ? 406 ARG   A CB  1 
ATOM   3049 C CG  . ARG   A 1 381 ? 146.485 132.715 122.341 1.00 62.62  ? 406 ARG   A CG  1 
ATOM   3050 C CD  . ARG   A 1 381 ? 147.855 132.177 122.668 1.00 63.00  ? 406 ARG   A CD  1 
ATOM   3051 N NE  . ARG   A 1 381 ? 148.584 133.092 123.538 1.00 62.34  ? 406 ARG   A NE  1 
ATOM   3052 C CZ  . ARG   A 1 381 ? 149.898 133.089 123.715 1.00 70.91  ? 406 ARG   A CZ  1 
ATOM   3053 N NH1 . ARG   A 1 381 ? 150.685 132.227 123.090 1.00 75.16  ? 406 ARG   A NH1 1 
ATOM   3054 N NH2 . ARG   A 1 381 ? 150.440 133.982 124.536 1.00 75.78  ? 406 ARG   A NH2 1 
ATOM   3055 N N   . SER   A 1 382 ? 144.014 131.144 118.700 1.00 61.61  ? 407 SER   A N   1 
ATOM   3056 C CA  . SER   A 1 382 ? 143.221 130.159 117.966 1.00 57.89  ? 407 SER   A CA  1 
ATOM   3057 C C   . SER   A 1 382 ? 144.163 129.123 117.369 1.00 58.26  ? 407 SER   A C   1 
ATOM   3058 O O   . SER   A 1 382 ? 144.922 129.429 116.445 1.00 61.84  ? 407 SER   A O   1 
ATOM   3059 C CB  . SER   A 1 382 ? 142.388 130.827 116.875 1.00 62.29  ? 407 SER   A CB  1 
ATOM   3060 O OG  . SER   A 1 382 ? 141.602 129.875 116.182 1.00 70.20  ? 407 SER   A OG  1 
ATOM   3061 N N   . HIS   A 1 383 ? 144.108 127.902 117.895 1.00 55.05  ? 408 HIS   A N   1 
ATOM   3062 C CA  . HIS   A 1 383 ? 144.945 126.808 117.428 1.00 55.01  ? 408 HIS   A CA  1 
ATOM   3063 C C   . HIS   A 1 383 ? 144.249 126.050 116.307 1.00 55.53  ? 408 HIS   A C   1 
ATOM   3064 O O   . HIS   A 1 383 ? 143.040 125.807 116.365 1.00 60.14  ? 408 HIS   A O   1 
ATOM   3065 C CB  . HIS   A 1 383 ? 145.265 125.855 118.578 1.00 56.79  ? 408 HIS   A CB  1 
ATOM   3066 C CG  . HIS   A 1 383 ? 145.870 126.531 119.768 1.00 58.40  ? 408 HIS   A CG  1 
ATOM   3067 N ND1 . HIS   A 1 383 ? 145.123 127.249 120.675 1.00 58.57  ? 408 HIS   A ND1 1 
ATOM   3068 C CD2 . HIS   A 1 383 ? 147.151 126.599 120.198 1.00 63.83  ? 408 HIS   A CD2 1 
ATOM   3069 C CE1 . HIS   A 1 383 ? 145.917 127.730 121.614 1.00 63.45  ? 408 HIS   A CE1 1 
ATOM   3070 N NE2 . HIS   A 1 383 ? 147.154 127.351 121.347 1.00 67.12  ? 408 HIS   A NE2 1 
ATOM   3071 N N   . GLN   A 1 384 ? 145.022 125.676 115.287 1.00 54.31  ? 409 GLN   A N   1 
ATOM   3072 C CA  . GLN   A 1 384 ? 144.514 124.953 114.127 1.00 52.01  ? 409 GLN   A CA  1 
ATOM   3073 C C   . GLN   A 1 384 ? 144.865 123.471 114.159 1.00 55.42  ? 409 GLN   A C   1 
ATOM   3074 O O   . GLN   A 1 384 ? 143.992 122.628 113.936 1.00 63.43  ? 409 GLN   A O   1 
ATOM   3075 C CB  . GLN   A 1 384 ? 145.059 125.590 112.842 1.00 53.96  ? 409 GLN   A CB  1 
ATOM   3076 C CG  . GLN   A 1 384 ? 144.555 124.981 111.534 1.00 54.15  ? 409 GLN   A CG  1 
ATOM   3077 C CD  . GLN   A 1 384 ? 143.061 125.128 111.347 1.00 61.98  ? 409 GLN   A CD  1 
ATOM   3078 O OE1 . GLN   A 1 384 ? 142.407 125.896 112.050 1.00 70.30  ? 409 GLN   A OE1 1 
ATOM   3079 N NE2 . GLN   A 1 384 ? 142.512 124.394 110.390 1.00 64.21  ? 409 GLN   A NE2 1 
ATOM   3080 N N   . HIS   A 1 385 ? 146.124 123.135 114.430 1.00 52.95  ? 410 HIS   A N   1 
ATOM   3081 C CA  . HIS   A 1 385 ? 146.580 121.757 114.347 1.00 51.67  ? 410 HIS   A CA  1 
ATOM   3082 C C   . HIS   A 1 385 ? 147.756 121.557 115.290 1.00 55.10  ? 410 HIS   A C   1 
ATOM   3083 O O   . HIS   A 1 385 ? 148.520 122.487 115.557 1.00 60.21  ? 410 HIS   A O   1 
ATOM   3084 C CB  . HIS   A 1 385 ? 146.978 121.407 112.911 1.00 53.87  ? 410 HIS   A CB  1 
ATOM   3085 C CG  . HIS   A 1 385 ? 147.118 119.941 112.660 1.00 54.17  ? 410 HIS   A CG  1 
ATOM   3086 N ND1 . HIS   A 1 385 ? 146.113 119.041 112.932 1.00 60.26  ? 410 HIS   A ND1 1 
ATOM   3087 C CD2 . HIS   A 1 385 ? 148.142 119.220 112.148 1.00 56.73  ? 410 HIS   A CD2 1 
ATOM   3088 C CE1 . HIS   A 1 385 ? 146.513 117.826 112.606 1.00 66.19  ? 410 HIS   A CE1 1 
ATOM   3089 N NE2 . HIS   A 1 385 ? 147.741 117.907 112.128 1.00 64.32  ? 410 HIS   A NE2 1 
ATOM   3090 N N   . VAL   A 1 386 ? 147.889 120.330 115.792 1.00 53.83  ? 411 VAL   A N   1 
ATOM   3091 C CA  . VAL   A 1 386 ? 148.984 119.944 116.676 1.00 51.89  ? 411 VAL   A CA  1 
ATOM   3092 C C   . VAL   A 1 386 ? 149.410 118.532 116.298 1.00 51.80  ? 411 VAL   A C   1 
ATOM   3093 O O   . VAL   A 1 386 ? 148.626 117.589 116.448 1.00 56.64  ? 411 VAL   A O   1 
ATOM   3094 C CB  . VAL   A 1 386 ? 148.582 120.000 118.159 1.00 54.86  ? 411 VAL   A CB  1 
ATOM   3095 C CG1 . VAL   A 1 386 ? 149.727 119.518 119.038 1.00 60.70  ? 411 VAL   A CG1 1 
ATOM   3096 C CG2 . VAL   A 1 386 ? 148.155 121.411 118.548 1.00 58.42  ? 411 VAL   A CG2 1 
ATOM   3097 N N   . LYS   A 1 387 ? 150.641 118.384 115.811 1.00 50.64  ? 412 LYS   A N   1 
ATOM   3098 C CA  . LYS   A 1 387 ? 151.189 117.097 115.401 1.00 53.96  ? 412 LYS   A CA  1 
ATOM   3099 C C   . LYS   A 1 387 ? 152.380 116.754 116.283 1.00 66.78  ? 412 LYS   A C   1 
ATOM   3100 O O   . LYS   A 1 387 ? 153.312 117.557 116.414 1.00 71.64  ? 412 LYS   A O   1 
ATOM   3101 C CB  . LYS   A 1 387 ? 151.615 117.126 113.933 1.00 55.82  ? 412 LYS   A CB  1 
ATOM   3102 C CG  . LYS   A 1 387 ? 151.921 115.758 113.357 1.00 59.36  ? 412 LYS   A CG  1 
ATOM   3103 C CD  . LYS   A 1 387 ? 152.222 115.816 111.868 1.00 60.92  ? 412 LYS   A CD  1 
ATOM   3104 C CE  . LYS   A 1 387 ? 153.683 116.092 111.596 1.00 62.00  ? 412 LYS   A CE  1 
ATOM   3105 N NZ  . LYS   A 1 387 ? 153.983 116.084 110.141 1.00 66.88  ? 412 LYS   A NZ  1 
ATOM   3106 N N   . ILE   A 1 388 ? 152.344 115.566 116.882 1.00 62.99  ? 413 ILE   A N   1 
ATOM   3107 C CA  . ILE   A 1 388 ? 153.424 115.055 117.721 1.00 55.77  ? 413 ILE   A CA  1 
ATOM   3108 C C   . ILE   A 1 388 ? 153.954 113.794 117.057 1.00 56.74  ? 413 ILE   A C   1 
ATOM   3109 O O   . ILE   A 1 388 ? 153.224 112.803 116.923 1.00 62.75  ? 413 ILE   A O   1 
ATOM   3110 C CB  . ILE   A 1 388 ? 152.958 114.771 119.160 1.00 57.10  ? 413 ILE   A CB  1 
ATOM   3111 C CG1 . ILE   A 1 388 ? 152.388 116.050 119.793 1.00 56.62  ? 413 ILE   A CG1 1 
ATOM   3112 C CG2 . ILE   A 1 388 ? 154.124 114.201 119.990 1.00 61.61  ? 413 ILE   A CG2 1 
ATOM   3113 C CD1 . ILE   A 1 388 ? 151.760 115.867 121.156 1.00 59.14  ? 413 ILE   A CD1 1 
ATOM   3114 N N   . THR   A 1 389 ? 155.222 113.829 116.659 1.00 56.31  ? 414 THR   A N   1 
ATOM   3115 C CA  . THR   A 1 389 ? 155.885 112.727 115.980 1.00 55.15  ? 414 THR   A CA  1 
ATOM   3116 C C   . THR   A 1 389 ? 156.931 112.120 116.903 1.00 61.43  ? 414 THR   A C   1 
ATOM   3117 O O   . THR   A 1 389 ? 157.531 112.822 117.720 1.00 69.90  ? 414 THR   A O   1 
ATOM   3118 C CB  . THR   A 1 389 ? 156.552 113.207 114.687 1.00 58.06  ? 414 THR   A CB  1 
ATOM   3119 O OG1 . THR   A 1 389 ? 155.584 113.866 113.863 1.00 68.86  ? 414 THR   A OG1 1 
ATOM   3120 C CG2 . THR   A 1 389 ? 157.153 112.041 113.916 1.00 61.54  ? 414 THR   A CG2 1 
ATOM   3121 N N   . TYR   A 1 390 ? 157.139 110.808 116.781 1.00 60.09  ? 415 TYR   A N   1 
ATOM   3122 C CA  . TYR   A 1 390 ? 158.158 110.115 117.557 1.00 59.29  ? 415 TYR   A CA  1 
ATOM   3123 C C   . TYR   A 1 390 ? 158.912 109.145 116.662 1.00 60.55  ? 415 TYR   A C   1 
ATOM   3124 O O   . TYR   A 1 390 ? 158.317 108.464 115.818 1.00 69.31  ? 415 TYR   A O   1 
ATOM   3125 C CB  . TYR   A 1 390 ? 157.552 109.376 118.764 1.00 62.01  ? 415 TYR   A CB  1 
ATOM   3126 C CG  . TYR   A 1 390 ? 156.939 108.026 118.469 1.00 58.97  ? 415 TYR   A CG  1 
ATOM   3127 C CD1 . TYR   A 1 390 ? 155.627 107.916 118.051 1.00 58.61  ? 415 TYR   A CD1 1 
ATOM   3128 C CD2 . TYR   A 1 390 ? 157.668 106.860 118.634 1.00 64.47  ? 415 TYR   A CD2 1 
ATOM   3129 C CE1 . TYR   A 1 390 ? 155.065 106.689 117.789 1.00 60.64  ? 415 TYR   A CE1 1 
ATOM   3130 C CE2 . TYR   A 1 390 ? 157.114 105.632 118.370 1.00 62.53  ? 415 TYR   A CE2 1 
ATOM   3131 C CZ  . TYR   A 1 390 ? 155.813 105.551 117.948 1.00 61.70  ? 415 TYR   A CZ  1 
ATOM   3132 O OH  . TYR   A 1 390 ? 155.255 104.322 117.688 1.00 75.32  ? 415 TYR   A OH  1 
ATOM   3133 N N   . ARG   A 1 391 ? 160.230 109.105 116.848 1.00 60.97  ? 416 ARG   A N   1 
ATOM   3134 C CA  . ARG   A 1 391 ? 161.115 108.167 116.169 1.00 62.59  ? 416 ARG   A CA  1 
ATOM   3135 C C   . ARG   A 1 391 ? 161.725 107.253 117.219 1.00 70.09  ? 416 ARG   A C   1 
ATOM   3136 O O   . ARG   A 1 391 ? 162.324 107.729 118.191 1.00 73.05  ? 416 ARG   A O   1 
ATOM   3137 C CB  . ARG   A 1 391 ? 162.205 108.900 115.382 1.00 67.18  ? 416 ARG   A CB  1 
ATOM   3138 C CG  . ARG   A 1 391 ? 163.145 107.980 114.608 1.00 73.74  ? 416 ARG   A CG  1 
ATOM   3139 C CD  . ARG   A 1 391 ? 164.219 108.744 113.844 1.00 75.06  ? 416 ARG   A CD  1 
ATOM   3140 N NE  . ARG   A 1 391 ? 163.730 109.301 112.586 1.00 77.05  ? 416 ARG   A NE  1 
ATOM   3141 C CZ  . ARG   A 1 391 ? 163.230 110.520 112.419 1.00 80.08  ? 416 ARG   A CZ  1 
ATOM   3142 N NH1 . ARG   A 1 391 ? 163.113 111.374 113.425 1.00 81.46  ? 416 ARG   A NH1 1 
ATOM   3143 N NH2 . ARG   A 1 391 ? 162.837 110.896 111.206 1.00 81.94  ? 416 ARG   A NH2 1 
ATOM   3144 N N   . ASP   A 1 392 ? 161.564 105.948 117.024 1.00 76.53  ? 417 ASP   A N   1 
ATOM   3145 C CA  . ASP   A 1 392 ? 162.117 104.969 117.947 1.00 75.67  ? 417 ASP   A CA  1 
ATOM   3146 C C   . ASP   A 1 392 ? 163.628 104.879 117.784 1.00 81.00  ? 417 ASP   A C   1 
ATOM   3147 O O   . ASP   A 1 392 ? 164.154 104.946 116.670 1.00 85.20  ? 417 ASP   A O   1 
ATOM   3148 C CB  . ASP   A 1 392 ? 161.475 103.604 117.706 1.00 78.14  ? 417 ASP   A CB  1 
ATOM   3149 C CG  . ASP   A 1 392 ? 162.040 102.530 118.605 1.00 88.55  ? 417 ASP   A CG  1 
ATOM   3150 O OD1 . ASP   A 1 392 ? 161.809 102.595 119.831 1.00 91.41  ? 417 ASP   A OD1 1 
ATOM   3151 O OD2 . ASP   A 1 392 ? 162.717 101.616 118.089 1.00 94.14  ? 417 ASP   A OD2 1 
ATOM   3152 N N   . GLY   A 1 393 ? 164.327 104.730 118.905 1.00 81.52  ? 418 GLY   A N   1 
ATOM   3153 C CA  . GLY   A 1 393 ? 165.771 104.662 118.920 1.00 81.23  ? 418 GLY   A CA  1 
ATOM   3154 C C   . GLY   A 1 393 ? 166.371 103.290 118.719 1.00 86.22  ? 418 GLY   A C   1 
ATOM   3155 O O   . GLY   A 1 393 ? 167.598 103.160 118.765 1.00 87.51  ? 418 GLY   A O   1 
ATOM   3156 N N   . ARG   A 1 394 ? 165.552 102.263 118.495 1.00 91.01  ? 419 ARG   A N   1 
ATOM   3157 C CA  . ARG   A 1 394 ? 166.010 100.893 118.280 1.00 92.14  ? 419 ARG   A CA  1 
ATOM   3158 C C   . ARG   A 1 394 ? 165.750 100.392 116.871 1.00 90.07  ? 419 ARG   A C   1 
ATOM   3159 O O   . ARG   A 1 394 ? 166.640 99.791  116.265 1.00 91.48  ? 419 ARG   A O   1 
ATOM   3160 C CB  . ARG   A 1 394 ? 165.327 99.950  119.280 1.00 95.12  ? 419 ARG   A CB  1 
ATOM   3161 C CG  . ARG   A 1 394 ? 165.784 98.490  119.210 1.00 98.41  ? 419 ARG   A CG  1 
ATOM   3162 C CD  . ARG   A 1 394 ? 165.102 97.634  120.268 1.00 104.80 ? 419 ARG   A CD  1 
ATOM   3163 N NE  . ARG   A 1 394 ? 163.650 97.637  120.123 1.00 108.29 ? 419 ARG   A NE  1 
ATOM   3164 C CZ  . ARG   A 1 394 ? 162.805 96.980  120.907 1.00 111.12 ? 419 ARG   A CZ  1 
ATOM   3165 N NH1 . ARG   A 1 394 ? 163.226 96.239  121.921 1.00 110.50 ? 419 ARG   A NH1 1 
ATOM   3166 N NH2 . ARG   A 1 394 ? 161.499 97.069  120.669 1.00 106.74 ? 419 ARG   A NH2 1 
ATOM   3167 N N   . THR   A 1 395 ? 164.553 100.630 116.336 1.00 85.17  ? 420 THR   A N   1 
ATOM   3168 C CA  . THR   A 1 395 ? 164.157 100.123 115.028 1.00 89.23  ? 420 THR   A CA  1 
ATOM   3169 C C   . THR   A 1 395 ? 164.170 101.189 113.944 1.00 88.65  ? 420 THR   A C   1 
ATOM   3170 O O   . THR   A 1 395 ? 164.378 100.857 112.772 1.00 88.61  ? 420 THR   A O   1 
ATOM   3171 C CB  . THR   A 1 395 ? 162.752 99.513  115.105 1.00 96.18  ? 420 THR   A CB  1 
ATOM   3172 O OG1 . THR   A 1 395 ? 162.688 98.592  116.201 1.00 95.81  ? 420 THR   A OG1 1 
ATOM   3173 C CG2 . THR   A 1 395 ? 162.406 98.777  113.812 1.00 94.99  ? 420 THR   A CG2 1 
ATOM   3174 N N   . GLY   A 1 396 ? 163.953 102.452 114.302 1.00 86.10  ? 421 GLY   A N   1 
ATOM   3175 C CA  . GLY   A 1 396 ? 163.868 103.530 113.341 1.00 82.52  ? 421 GLY   A CA  1 
ATOM   3176 C C   . GLY   A 1 396 ? 162.469 103.840 112.857 1.00 80.13  ? 421 GLY   A C   1 
ATOM   3177 O O   . GLY   A 1 396 ? 162.316 104.685 111.969 1.00 76.16  ? 421 GLY   A O   1 
ATOM   3178 N N   . GLU   A 1 397 ? 161.448 103.192 113.410 1.00 81.50  ? 422 GLU   A N   1 
ATOM   3179 C CA  . GLU   A 1 397 ? 160.081 103.454 112.993 1.00 79.08  ? 422 GLU   A CA  1 
ATOM   3180 C C   . GLU   A 1 397 ? 159.669 104.868 113.379 1.00 77.38  ? 422 GLU   A C   1 
ATOM   3181 O O   . GLU   A 1 397 ? 160.119 105.416 114.388 1.00 82.53  ? 422 GLU   A O   1 
ATOM   3182 C CB  . GLU   A 1 397 ? 159.126 102.444 113.628 1.00 88.97  ? 422 GLU   A CB  1 
ATOM   3183 C CG  . GLU   A 1 397 ? 159.436 100.996 113.293 1.00 93.60  ? 422 GLU   A CG  1 
ATOM   3184 C CD  . GLU   A 1 397 ? 158.452 100.031 113.920 1.00 102.21 ? 422 GLU   A CD  1 
ATOM   3185 O OE1 . GLU   A 1 397 ? 157.529 100.495 114.622 1.00 103.58 ? 422 GLU   A OE1 1 
ATOM   3186 O OE2 . GLU   A 1 397 ? 158.600 98.808  113.712 1.00 104.98 ? 422 GLU   A OE2 1 
ATOM   3187 N N   . LEU   A 1 398 ? 158.799 105.452 112.559 1.00 69.79  ? 423 LEU   A N   1 
ATOM   3188 C CA  . LEU   A 1 398 ? 158.300 106.809 112.747 1.00 65.80  ? 423 LEU   A CA  1 
ATOM   3189 C C   . LEU   A 1 398 ? 156.793 106.735 112.925 1.00 63.63  ? 423 LEU   A C   1 
ATOM   3190 O O   . LEU   A 1 398 ? 156.093 106.198 112.060 1.00 67.11  ? 423 LEU   A O   1 
ATOM   3191 C CB  . LEU   A 1 398 ? 158.669 107.689 111.552 1.00 64.77  ? 423 LEU   A CB  1 
ATOM   3192 C CG  . LEU   A 1 398 ? 158.475 109.199 111.687 1.00 68.52  ? 423 LEU   A CG  1 
ATOM   3193 C CD1 . LEU   A 1 398 ? 159.396 109.781 112.748 1.00 71.18  ? 423 LEU   A CD1 1 
ATOM   3194 C CD2 . LEU   A 1 398 ? 158.713 109.875 110.351 1.00 69.24  ? 423 LEU   A CD2 1 
ATOM   3195 N N   . GLY   A 1 399 ? 156.297 107.265 114.049 1.00 60.00  ? 424 GLY   A N   1 
ATOM   3196 C CA  . GLY   A 1 399 ? 154.885 107.208 114.356 1.00 56.61  ? 424 GLY   A CA  1 
ATOM   3197 C C   . GLY   A 1 399 ? 154.397 108.533 114.906 1.00 56.81  ? 424 GLY   A C   1 
ATOM   3198 O O   . GLY   A 1 399 ? 155.181 109.450 115.155 1.00 68.61  ? 424 GLY   A O   1 
ATOM   3199 N N   . TYR   A 1 400 ? 153.081 108.616 115.084 1.00 46.46  ? 425 TYR   A N   1 
ATOM   3200 C CA  . TYR   A 1 400 ? 152.409 109.844 115.485 1.00 50.13  ? 425 TYR   A CA  1 
ATOM   3201 C C   . TYR   A 1 400 ? 151.572 109.575 116.724 1.00 53.31  ? 425 TYR   A C   1 
ATOM   3202 O O   . TYR   A 1 400 ? 150.791 108.620 116.751 1.00 62.80  ? 425 TYR   A O   1 
ATOM   3203 C CB  . TYR   A 1 400 ? 151.535 110.376 114.344 1.00 54.44  ? 425 TYR   A CB  1 
ATOM   3204 C CG  . TYR   A 1 400 ? 152.274 110.490 113.029 1.00 55.83  ? 425 TYR   A CG  1 
ATOM   3205 C CD1 . TYR   A 1 400 ? 152.310 109.429 112.139 1.00 61.45  ? 425 TYR   A CD1 1 
ATOM   3206 C CD2 . TYR   A 1 400 ? 152.941 111.651 112.683 1.00 56.39  ? 425 TYR   A CD2 1 
ATOM   3207 C CE1 . TYR   A 1 400 ? 152.987 109.523 110.946 1.00 61.91  ? 425 TYR   A CE1 1 
ATOM   3208 C CE2 . TYR   A 1 400 ? 153.620 111.753 111.490 1.00 61.00  ? 425 TYR   A CE2 1 
ATOM   3209 C CZ  . TYR   A 1 400 ? 153.641 110.685 110.625 1.00 63.43  ? 425 TYR   A CZ  1 
ATOM   3210 O OH  . TYR   A 1 400 ? 154.314 110.779 109.432 1.00 70.21  ? 425 TYR   A OH  1 
ATOM   3211 N N   . LEU   A 1 401 ? 151.737 110.412 117.743 1.00 53.41  ? 426 LEU   A N   1 
ATOM   3212 C CA  . LEU   A 1 401 ? 150.987 110.295 118.985 1.00 51.47  ? 426 LEU   A CA  1 
ATOM   3213 C C   . LEU   A 1 401 ? 149.760 111.194 118.950 1.00 57.15  ? 426 LEU   A C   1 
ATOM   3214 O O   . LEU   A 1 401 ? 149.675 112.142 118.165 1.00 59.39  ? 426 LEU   A O   1 
ATOM   3215 C CB  . LEU   A 1 401 ? 151.856 110.664 120.191 1.00 52.81  ? 426 LEU   A CB  1 
ATOM   3216 C CG  . LEU   A 1 401 ? 153.131 109.856 120.424 1.00 60.06  ? 426 LEU   A CG  1 
ATOM   3217 C CD1 . LEU   A 1 401 ? 153.885 110.429 121.605 1.00 62.88  ? 426 LEU   A CD1 1 
ATOM   3218 C CD2 . LEU   A 1 401 ? 152.828 108.386 120.652 1.00 63.99  ? 426 LEU   A CD2 1 
ATOM   3219 N N   . ASN   A 1 402 ? 148.802 110.882 119.813 1.00 59.44  ? 427 ASN   A N   1 
ATOM   3220 C CA  . ASN   A 1 402 ? 147.633 111.733 119.940 1.00 56.06  ? 427 ASN   A CA  1 
ATOM   3221 C C   . ASN   A 1 402 ? 148.059 113.076 120.534 1.00 59.84  ? 427 ASN   A C   1 
ATOM   3222 O O   . ASN   A 1 402 ? 148.970 113.113 121.367 1.00 66.37  ? 427 ASN   A O   1 
ATOM   3223 C CB  . ASN   A 1 402 ? 146.579 111.064 120.825 1.00 56.92  ? 427 ASN   A CB  1 
ATOM   3224 C CG  . ASN   A 1 402 ? 145.152 111.383 120.405 1.00 62.01  ? 427 ASN   A CG  1 
ATOM   3225 O OD1 . ASN   A 1 402 ? 144.882 111.748 119.262 1.00 66.53  ? 427 ASN   A OD1 1 
ATOM   3226 N ND2 . ASN   A 1 402 ? 144.223 111.226 121.339 1.00 65.09  ? 427 ASN   A ND2 1 
ATOM   3227 N N   . PRO   A 1 403 ? 147.451 114.197 120.111 1.00 53.44  ? 428 PRO   A N   1 
ATOM   3228 C CA  . PRO   A 1 403 ? 147.988 115.505 120.534 1.00 56.01  ? 428 PRO   A CA  1 
ATOM   3229 C C   . PRO   A 1 403 ? 148.030 115.729 122.037 1.00 59.95  ? 428 PRO   A C   1 
ATOM   3230 O O   . PRO   A 1 403 ? 149.013 116.290 122.535 1.00 66.50  ? 428 PRO   A O   1 
ATOM   3231 C CB  . PRO   A 1 403 ? 147.041 116.502 119.853 1.00 58.07  ? 428 PRO   A CB  1 
ATOM   3232 C CG  . PRO   A 1 403 ? 146.474 115.779 118.720 1.00 61.07  ? 428 PRO   A CG  1 
ATOM   3233 C CD  . PRO   A 1 403 ? 146.332 114.367 119.166 1.00 59.45  ? 428 PRO   A CD  1 
ATOM   3234 N N   . GLY   A 1 404 ? 147.009 115.295 122.773 1.00 55.34  ? 429 GLY   A N   1 
ATOM   3235 C CA  . GLY   A 1 404 ? 146.883 115.620 124.183 1.00 57.11  ? 429 GLY   A CA  1 
ATOM   3236 C C   . GLY   A 1 404 ? 146.893 114.430 125.117 1.00 58.17  ? 429 GLY   A C   1 
ATOM   3237 O O   . GLY   A 1 404 ? 146.148 114.411 126.100 1.00 61.81  ? 429 GLY   A O   1 
ATOM   3238 N N   . VAL   A 1 405 ? 147.723 113.437 124.839 1.00 54.70  ? 430 VAL   A N   1 
ATOM   3239 C CA  . VAL   A 1 405 ? 147.737 112.221 125.644 1.00 52.64  ? 430 VAL   A CA  1 
ATOM   3240 C C   . VAL   A 1 405 ? 148.472 112.480 126.951 1.00 60.76  ? 430 VAL   A C   1 
ATOM   3241 O O   . VAL   A 1 405 ? 149.473 113.206 126.987 1.00 66.93  ? 430 VAL   A O   1 
ATOM   3242 C CB  . VAL   A 1 405 ? 148.371 111.058 124.858 1.00 56.55  ? 430 VAL   A CB  1 
ATOM   3243 C CG1 . VAL   A 1 405 ? 149.864 111.301 124.605 1.00 61.01  ? 430 VAL   A CG1 1 
ATOM   3244 C CG2 . VAL   A 1 405 ? 148.147 109.730 125.580 1.00 62.01  ? 430 VAL   A CG2 1 
ATOM   3245 N N   . PHE   A 1 406 ? 147.971 111.879 128.032 1.00 61.42  ? 431 PHE   A N   1 
ATOM   3246 C CA  . PHE   A 1 406 ? 148.585 111.983 129.357 1.00 59.38  ? 431 PHE   A CA  1 
ATOM   3247 C C   . PHE   A 1 406 ? 148.672 113.433 129.826 1.00 60.87  ? 431 PHE   A C   1 
ATOM   3248 O O   . PHE   A 1 406 ? 149.663 113.846 130.431 1.00 68.49  ? 431 PHE   A O   1 
ATOM   3249 C CB  . PHE   A 1 406 ? 149.974 111.340 129.373 1.00 60.75  ? 431 PHE   A CB  1 
ATOM   3250 C CG  . PHE   A 1 406 ? 150.005 109.926 128.869 1.00 58.84  ? 431 PHE   A CG  1 
ATOM   3251 C CD1 . PHE   A 1 406 ? 149.020 109.023 129.212 1.00 65.27  ? 431 PHE   A CD1 1 
ATOM   3252 C CD2 . PHE   A 1 406 ? 151.037 109.501 128.058 1.00 55.76  ? 431 PHE   A CD2 1 
ATOM   3253 C CE1 . PHE   A 1 406 ? 149.062 107.730 128.748 1.00 67.80  ? 431 PHE   A CE1 1 
ATOM   3254 C CE2 . PHE   A 1 406 ? 151.083 108.213 127.592 1.00 56.77  ? 431 PHE   A CE2 1 
ATOM   3255 C CZ  . PHE   A 1 406 ? 150.096 107.324 127.937 1.00 65.58  ? 431 PHE   A CZ  1 
ATOM   3256 N N   . THR   A 1 407 ? 147.632 114.214 129.548 1.00 55.62  ? 432 THR   A N   1 
ATOM   3257 C CA  . THR   A 1 407 ? 147.593 115.616 129.935 1.00 59.93  ? 432 THR   A CA  1 
ATOM   3258 C C   . THR   A 1 407 ? 146.166 116.003 130.292 1.00 64.64  ? 432 THR   A C   1 
ATOM   3259 O O   . THR   A 1 407 ? 145.205 115.379 129.835 1.00 68.31  ? 432 THR   A O   1 
ATOM   3260 C CB  . THR   A 1 407 ? 148.118 116.524 128.818 1.00 62.90  ? 432 THR   A CB  1 
ATOM   3261 O OG1 . THR   A 1 407 ? 149.237 115.900 128.178 1.00 65.26  ? 432 THR   A OG1 1 
ATOM   3262 C CG2 . THR   A 1 407 ? 148.557 117.869 129.376 1.00 63.79  ? 432 THR   A CG2 1 
ATOM   3263 N N   . GLN   A 1 408 ? 146.045 117.045 131.118 1.00 63.24  ? 433 GLN   A N   1 
ATOM   3264 C CA  . GLN   A 1 408 ? 144.763 117.534 131.601 1.00 57.05  ? 433 GLN   A CA  1 
ATOM   3265 C C   . GLN   A 1 408 ? 144.455 118.966 131.188 1.00 56.50  ? 433 GLN   A C   1 
ATOM   3266 O O   . GLN   A 1 408 ? 143.290 119.368 131.260 1.00 65.63  ? 433 GLN   A O   1 
ATOM   3267 C CB  . GLN   A 1 408 ? 144.707 117.443 133.133 1.00 59.46  ? 433 GLN   A CB  1 
ATOM   3268 C CG  . GLN   A 1 408 ? 144.817 116.029 133.669 1.00 63.21  ? 433 GLN   A CG  1 
ATOM   3269 C CD  . GLN   A 1 408 ? 144.939 115.983 135.175 1.00 69.93  ? 433 GLN   A CD  1 
ATOM   3270 O OE1 . GLN   A 1 408 ? 144.971 117.019 135.838 1.00 71.98  ? 433 GLN   A OE1 1 
ATOM   3271 N NE2 . GLN   A 1 408 ? 145.008 114.780 135.724 1.00 71.01  ? 433 GLN   A NE2 1 
ATOM   3272 N N   . SER   A 1 409 ? 145.451 119.740 130.762 1.00 54.77  ? 434 SER   A N   1 
ATOM   3273 C CA  . SER   A 1 409 ? 145.268 121.109 130.307 1.00 58.59  ? 434 SER   A CA  1 
ATOM   3274 C C   . SER   A 1 409 ? 145.935 121.278 128.951 1.00 58.27  ? 434 SER   A C   1 
ATOM   3275 O O   . SER   A 1 409 ? 146.751 120.456 128.528 1.00 62.39  ? 434 SER   A O   1 
ATOM   3276 C CB  . SER   A 1 409 ? 145.842 122.114 131.311 1.00 66.77  ? 434 SER   A CB  1 
ATOM   3277 O OG  . SER   A 1 409 ? 145.626 123.444 130.872 1.00 73.85  ? 434 SER   A OG  1 
ATOM   3278 N N   . ARG   A 1 410 ? 145.580 122.370 128.274 1.00 58.84  ? 435 ARG   A N   1 
ATOM   3279 C CA  . ARG   A 1 410 ? 145.997 122.629 126.901 1.00 62.94  ? 435 ARG   A CA  1 
ATOM   3280 C C   . ARG   A 1 410 ? 146.746 123.952 126.785 1.00 67.05  ? 435 ARG   A C   1 
ATOM   3281 O O   . ARG   A 1 410 ? 146.699 124.606 125.741 1.00 71.50  ? 435 ARG   A O   1 
ATOM   3282 C CB  . ARG   A 1 410 ? 144.792 122.603 125.962 1.00 72.20  ? 435 ARG   A CB  1 
ATOM   3283 C CG  . ARG   A 1 410 ? 143.674 123.556 126.351 1.00 77.41  ? 435 ARG   A CG  1 
ATOM   3284 C CD  . ARG   A 1 410 ? 142.514 123.486 125.370 1.00 85.41  ? 435 ARG   A CD  1 
ATOM   3285 N NE  . ARG   A 1 410 ? 141.912 122.158 125.319 1.00 90.74  ? 435 ARG   A NE  1 
ATOM   3286 C CZ  . ARG   A 1 410 ? 140.872 121.824 124.565 1.00 96.56  ? 435 ARG   A CZ  1 
ATOM   3287 N NH1 . ARG   A 1 410 ? 140.274 122.702 123.773 1.00 96.73  ? 435 ARG   A NH1 1 
ATOM   3288 N NH2 . ARG   A 1 410 ? 140.417 120.575 124.607 1.00 93.62  ? 435 ARG   A NH2 1 
ATOM   3289 N N   . ARG   A 1 411 ? 147.440 124.359 127.848 1.00 64.30  ? 436 ARG   A N   1 
ATOM   3290 C CA  . ARG   A 1 411 ? 148.326 125.514 127.813 1.00 60.31  ? 436 ARG   A CA  1 
ATOM   3291 C C   . ARG   A 1 411 ? 149.765 125.149 127.474 1.00 60.97  ? 436 ARG   A C   1 
ATOM   3292 O O   . ARG   A 1 411 ? 150.610 126.045 127.392 1.00 63.13  ? 436 ARG   A O   1 
ATOM   3293 C CB  . ARG   A 1 411 ? 148.294 126.248 129.155 1.00 64.77  ? 436 ARG   A CB  1 
ATOM   3294 C CG  . ARG   A 1 411 ? 147.028 127.034 129.404 1.00 69.62  ? 436 ARG   A CG  1 
ATOM   3295 C CD  . ARG   A 1 411 ? 147.234 128.038 130.517 1.00 71.65  ? 436 ARG   A CD  1 
ATOM   3296 N NE  . ARG   A 1 411 ? 145.978 128.605 130.988 1.00 75.88  ? 436 ARG   A NE  1 
ATOM   3297 C CZ  . ARG   A 1 411 ? 145.864 129.447 132.007 1.00 78.95  ? 436 ARG   A CZ  1 
ATOM   3298 N NH1 . ARG   A 1 411 ? 146.920 129.862 132.690 1.00 72.22  ? 436 ARG   A NH1 1 
ATOM   3299 N NH2 . ARG   A 1 411 ? 144.657 129.884 132.354 1.00 79.70  ? 436 ARG   A NH2 1 
ATOM   3300 N N   . TRP   A 1 412 ? 150.066 123.868 127.272 1.00 57.15  ? 437 TRP   A N   1 
ATOM   3301 C CA  . TRP   A 1 412 ? 151.392 123.453 126.832 1.00 56.45  ? 437 TRP   A CA  1 
ATOM   3302 C C   . TRP   A 1 412 ? 151.650 123.747 125.361 1.00 59.30  ? 437 TRP   A C   1 
ATOM   3303 O O   . TRP   A 1 412 ? 152.774 123.533 124.897 1.00 63.99  ? 437 TRP   A O   1 
ATOM   3304 C CB  . TRP   A 1 412 ? 151.604 121.957 127.098 1.00 55.10  ? 437 TRP   A CB  1 
ATOM   3305 C CG  . TRP   A 1 412 ? 150.613 121.055 126.430 1.00 56.20  ? 437 TRP   A CG  1 
ATOM   3306 C CD1 . TRP   A 1 412 ? 149.468 120.565 126.971 1.00 59.33  ? 437 TRP   A CD1 1 
ATOM   3307 C CD2 . TRP   A 1 412 ? 150.681 120.535 125.099 1.00 56.02  ? 437 TRP   A CD2 1 
ATOM   3308 N NE1 . TRP   A 1 412 ? 148.814 119.774 126.064 1.00 59.64  ? 437 TRP   A NE1 1 
ATOM   3309 C CE2 . TRP   A 1 412 ? 149.539 119.740 124.904 1.00 52.86  ? 437 TRP   A CE2 1 
ATOM   3310 C CE3 . TRP   A 1 412 ? 151.595 120.668 124.051 1.00 63.08  ? 437 TRP   A CE3 1 
ATOM   3311 C CZ2 . TRP   A 1 412 ? 149.285 119.082 123.711 1.00 57.40  ? 437 TRP   A CZ2 1 
ATOM   3312 C CZ3 . TRP   A 1 412 ? 151.341 120.012 122.866 1.00 64.03  ? 437 TRP   A CZ3 1 
ATOM   3313 C CH2 . TRP   A 1 412 ? 150.196 119.228 122.706 1.00 63.58  ? 437 TRP   A CH2 1 
ATOM   3314 N N   . LYS   A 1 413 ? 150.656 124.226 124.620 1.00 57.41  ? 438 LYS   A N   1 
ATOM   3315 C CA  . LYS   A 1 413 ? 150.821 124.557 123.213 1.00 59.98  ? 438 LYS   A CA  1 
ATOM   3316 C C   . LYS   A 1 413 ? 151.390 125.952 122.995 1.00 63.86  ? 438 LYS   A C   1 
ATOM   3317 O O   . LYS   A 1 413 ? 151.589 126.343 121.840 1.00 67.51  ? 438 LYS   A O   1 
ATOM   3318 C CB  . LYS   A 1 413 ? 149.477 124.448 122.485 1.00 64.25  ? 438 LYS   A CB  1 
ATOM   3319 C CG  . LYS   A 1 413 ? 148.767 123.113 122.633 1.00 65.46  ? 438 LYS   A CG  1 
ATOM   3320 C CD  . LYS   A 1 413 ? 147.402 123.152 121.971 1.00 70.64  ? 438 LYS   A CD  1 
ATOM   3321 C CE  . LYS   A 1 413 ? 146.618 121.879 122.224 1.00 74.31  ? 438 LYS   A CE  1 
ATOM   3322 N NZ  . LYS   A 1 413 ? 145.241 121.958 121.673 1.00 74.38  ? 438 LYS   A NZ  1 
ATOM   3323 N N   . ASP   A 1 414 ? 151.653 126.709 124.067 1.00 62.34  ? 439 ASP   A N   1 
ATOM   3324 C CA  . ASP   A 1 414 ? 152.067 128.100 123.964 1.00 62.29  ? 439 ASP   A CA  1 
ATOM   3325 C C   . ASP   A 1 414 ? 153.264 128.464 124.832 1.00 63.71  ? 439 ASP   A C   1 
ATOM   3326 O O   . ASP   A 1 414 ? 153.688 129.624 124.801 1.00 68.10  ? 439 ASP   A O   1 
ATOM   3327 C CB  . ASP   A 1 414 ? 150.895 129.023 124.325 1.00 64.62  ? 439 ASP   A CB  1 
ATOM   3328 C CG  . ASP   A 1 414 ? 149.751 128.925 123.337 1.00 76.19  ? 439 ASP   A CG  1 
ATOM   3329 O OD1 . ASP   A 1 414 ? 150.019 128.792 122.125 1.00 75.99  ? 439 ASP   A OD1 1 
ATOM   3330 O OD2 . ASP   A 1 414 ? 148.581 128.975 123.772 1.00 83.04  ? 439 ASP   A OD2 1 
ATOM   3331 N N   . HIS   A 1 415 ? 153.818 127.526 125.602 1.00 59.03  ? 440 HIS   A N   1 
ATOM   3332 C CA  . HIS   A 1 415 ? 154.957 127.788 126.472 1.00 56.31  ? 440 HIS   A CA  1 
ATOM   3333 C C   . HIS   A 1 415 ? 156.014 126.716 126.256 1.00 62.48  ? 440 HIS   A C   1 
ATOM   3334 O O   . HIS   A 1 415 ? 155.694 125.525 126.203 1.00 68.48  ? 440 HIS   A O   1 
ATOM   3335 C CB  . HIS   A 1 415 ? 154.526 127.829 127.938 1.00 59.31  ? 440 HIS   A CB  1 
ATOM   3336 C CG  . HIS   A 1 415 ? 153.541 128.914 128.246 1.00 58.26  ? 440 HIS   A CG  1 
ATOM   3337 N ND1 . HIS   A 1 415 ? 152.179 128.732 128.155 1.00 59.10  ? 440 HIS   A ND1 1 
ATOM   3338 C CD2 . HIS   A 1 415 ? 153.723 130.196 128.637 1.00 58.66  ? 440 HIS   A CD2 1 
ATOM   3339 C CE1 . HIS   A 1 415 ? 151.564 129.855 128.480 1.00 55.79  ? 440 HIS   A CE1 1 
ATOM   3340 N NE2 . HIS   A 1 415 ? 152.478 130.759 128.777 1.00 53.47  ? 440 HIS   A NE2 1 
ATOM   3341 N N   . ALA   A 1 416 ? 157.274 127.144 126.137 1.00 58.12  ? 441 ALA   A N   1 
ATOM   3342 C CA  . ALA   A 1 416 ? 158.350 126.210 125.821 1.00 58.40  ? 441 ALA   A CA  1 
ATOM   3343 C C   . ALA   A 1 416 ? 158.668 125.294 126.995 1.00 60.25  ? 441 ALA   A C   1 
ATOM   3344 O O   . ALA   A 1 416 ? 158.928 124.100 126.803 1.00 65.34  ? 441 ALA   A O   1 
ATOM   3345 C CB  . ALA   A 1 416 ? 159.599 126.977 125.396 1.00 59.71  ? 441 ALA   A CB  1 
ATOM   3346 N N   . ASP   A 1 417 ? 158.680 125.835 128.215 1.00 58.55  ? 442 ASP   A N   1 
ATOM   3347 C CA  . ASP   A 1 417 ? 159.043 125.031 129.379 1.00 60.52  ? 442 ASP   A CA  1 
ATOM   3348 C C   . ASP   A 1 417 ? 158.048 123.899 129.603 1.00 63.01  ? 442 ASP   A C   1 
ATOM   3349 O O   . ASP   A 1 417 ? 158.438 122.768 129.932 1.00 65.71  ? 442 ASP   A O   1 
ATOM   3350 C CB  . ASP   A 1 417 ? 159.141 125.922 130.617 1.00 64.96  ? 442 ASP   A CB  1 
ATOM   3351 C CG  . ASP   A 1 417 ? 157.857 126.668 130.907 1.00 70.62  ? 442 ASP   A CG  1 
ATOM   3352 O OD1 . ASP   A 1 417 ? 157.185 127.088 129.944 1.00 65.98  ? 442 ASP   A OD1 1 
ATOM   3353 O OD2 . ASP   A 1 417 ? 157.521 126.836 132.098 1.00 80.68  ? 442 ASP   A OD2 1 
ATOM   3354 N N   . MET   A 1 418 ? 156.758 124.181 129.430 1.00 59.98  ? 443 MET   A N   1 
ATOM   3355 C CA  . MET   A 1 418 ? 155.755 123.136 129.561 1.00 61.11  ? 443 MET   A CA  1 
ATOM   3356 C C   . MET   A 1 418 ? 155.930 122.085 128.476 1.00 61.62  ? 443 MET   A C   1 
ATOM   3357 O O   . MET   A 1 418 ? 155.709 120.892 128.713 1.00 65.11  ? 443 MET   A O   1 
ATOM   3358 C CB  . MET   A 1 418 ? 154.359 123.752 129.514 1.00 61.57  ? 443 MET   A CB  1 
ATOM   3359 C CG  . MET   A 1 418 ? 154.072 124.694 130.679 1.00 62.59  ? 443 MET   A CG  1 
ATOM   3360 S SD  . MET   A 1 418 ? 152.545 125.628 130.509 1.00 70.88  ? 443 MET   A SD  1 
ATOM   3361 C CE  . MET   A 1 418 ? 151.348 124.302 130.423 1.00 68.93  ? 443 MET   A CE  1 
ATOM   3362 N N   . LEU   A 1 419 ? 156.345 122.509 127.283 1.00 59.20  ? 444 LEU   A N   1 
ATOM   3363 C CA  . LEU   A 1 419 ? 156.637 121.556 126.220 1.00 55.21  ? 444 LEU   A CA  1 
ATOM   3364 C C   . LEU   A 1 419 ? 157.797 120.649 126.605 1.00 55.84  ? 444 LEU   A C   1 
ATOM   3365 O O   . LEU   A 1 419 ? 157.760 119.440 126.348 1.00 63.38  ? 444 LEU   A O   1 
ATOM   3366 C CB  . LEU   A 1 419 ? 156.946 122.305 124.927 1.00 53.12  ? 444 LEU   A CB  1 
ATOM   3367 C CG  . LEU   A 1 419 ? 156.693 121.552 123.624 1.00 58.54  ? 444 LEU   A CG  1 
ATOM   3368 C CD1 . LEU   A 1 419 ? 155.205 121.493 123.317 1.00 59.27  ? 444 LEU   A CD1 1 
ATOM   3369 C CD2 . LEU   A 1 419 ? 157.462 122.199 122.488 1.00 63.41  ? 444 LEU   A CD2 1 
ATOM   3370 N N   . LYS   A 1 420 ? 158.836 121.213 127.223 1.00 51.55  ? 445 LYS   A N   1 
ATOM   3371 C CA  . LYS   A 1 420 ? 159.968 120.399 127.660 1.00 52.34  ? 445 LYS   A CA  1 
ATOM   3372 C C   . LYS   A 1 420 ? 159.538 119.387 128.716 1.00 60.02  ? 445 LYS   A C   1 
ATOM   3373 O O   . LYS   A 1 420 ? 159.941 118.214 128.672 1.00 67.03  ? 445 LYS   A O   1 
ATOM   3374 C CB  . LYS   A 1 420 ? 161.072 121.304 128.204 1.00 54.44  ? 445 LYS   A CB  1 
ATOM   3375 C CG  . LYS   A 1 420 ? 162.410 120.628 128.451 1.00 54.17  ? 445 LYS   A CG  1 
ATOM   3376 C CD  . LYS   A 1 420 ? 163.142 120.327 127.164 1.00 56.15  ? 445 LYS   A CD  1 
ATOM   3377 C CE  . LYS   A 1 420 ? 164.545 119.819 127.431 1.00 60.61  ? 445 LYS   A CE  1 
ATOM   3378 N NZ  . LYS   A 1 420 ? 164.552 118.558 128.213 1.00 63.59  ? 445 LYS   A NZ  1 
ATOM   3379 N N   . GLN   A 1 421 ? 158.720 119.824 129.674 1.00 58.77  ? 446 GLN   A N   1 
ATOM   3380 C CA  . GLN   A 1 421 ? 158.242 118.910 130.706 1.00 55.26  ? 446 GLN   A CA  1 
ATOM   3381 C C   . GLN   A 1 421 ? 157.390 117.799 130.106 1.00 58.31  ? 446 GLN   A C   1 
ATOM   3382 O O   . GLN   A 1 421 ? 157.512 116.630 130.495 1.00 63.14  ? 446 GLN   A O   1 
ATOM   3383 C CB  . GLN   A 1 421 ? 157.456 119.681 131.762 1.00 57.93  ? 446 GLN   A CB  1 
ATOM   3384 C CG  . GLN   A 1 421 ? 158.310 120.626 132.580 1.00 63.52  ? 446 GLN   A CG  1 
ATOM   3385 C CD  . GLN   A 1 421 ? 157.545 121.270 133.711 1.00 64.84  ? 446 GLN   A CD  1 
ATOM   3386 O OE1 . GLN   A 1 421 ? 156.402 121.687 133.541 1.00 62.50  ? 446 GLN   A OE1 1 
ATOM   3387 N NE2 . GLN   A 1 421 ? 158.170 121.348 134.877 1.00 71.93  ? 446 GLN   A NE2 1 
ATOM   3388 N N   . TYR   A 1 422 ? 156.525 118.145 129.150 1.00 58.03  ? 447 TYR   A N   1 
ATOM   3389 C CA  . TYR   A 1 422 ? 155.702 117.139 128.488 1.00 54.76  ? 447 TYR   A CA  1 
ATOM   3390 C C   . TYR   A 1 422 ? 156.566 116.146 127.727 1.00 57.13  ? 447 TYR   A C   1 
ATOM   3391 O O   . TYR   A 1 422 ? 156.284 114.942 127.720 1.00 63.99  ? 447 TYR   A O   1 
ATOM   3392 C CB  . TYR   A 1 422 ? 154.709 117.826 127.548 1.00 54.00  ? 447 TYR   A CB  1 
ATOM   3393 C CG  . TYR   A 1 422 ? 153.667 116.935 126.897 1.00 53.27  ? 447 TYR   A CG  1 
ATOM   3394 C CD1 . TYR   A 1 422 ? 153.238 115.760 127.491 1.00 56.78  ? 447 TYR   A CD1 1 
ATOM   3395 C CD2 . TYR   A 1 422 ? 153.103 117.285 125.684 1.00 56.75  ? 447 TYR   A CD2 1 
ATOM   3396 C CE1 . TYR   A 1 422 ? 152.289 114.966 126.893 1.00 57.49  ? 447 TYR   A CE1 1 
ATOM   3397 C CE2 . TYR   A 1 422 ? 152.156 116.495 125.084 1.00 56.04  ? 447 TYR   A CE2 1 
ATOM   3398 C CZ  . TYR   A 1 422 ? 151.752 115.337 125.692 1.00 57.53  ? 447 TYR   A CZ  1 
ATOM   3399 O OH  . TYR   A 1 422 ? 150.804 114.547 125.090 1.00 67.39  ? 447 TYR   A OH  1 
ATOM   3400 N N   . ALA   A 1 423 ? 157.618 116.635 127.069 1.00 54.86  ? 448 ALA   A N   1 
ATOM   3401 C CA  . ALA   A 1 423 ? 158.515 115.743 126.347 1.00 55.35  ? 448 ALA   A CA  1 
ATOM   3402 C C   . ALA   A 1 423 ? 159.206 114.772 127.294 1.00 59.60  ? 448 ALA   A C   1 
ATOM   3403 O O   . ALA   A 1 423 ? 159.322 113.579 126.991 1.00 68.71  ? 448 ALA   A O   1 
ATOM   3404 C CB  . ALA   A 1 423 ? 159.546 116.555 125.568 1.00 56.88  ? 448 ALA   A CB  1 
ATOM   3405 N N   . THR   A 1 424 ? 159.667 115.257 128.447 1.00 53.75  ? 449 THR   A N   1 
ATOM   3406 C CA  . THR   A 1 424 ? 160.304 114.357 129.408 1.00 55.82  ? 449 THR   A CA  1 
ATOM   3407 C C   . THR   A 1 424 ? 159.313 113.330 129.949 1.00 62.14  ? 449 THR   A C   1 
ATOM   3408 O O   . THR   A 1 424 ? 159.657 112.149 130.122 1.00 66.50  ? 449 THR   A O   1 
ATOM   3409 C CB  . THR   A 1 424 ? 160.922 115.159 130.550 1.00 58.99  ? 449 THR   A CB  1 
ATOM   3410 O OG1 . THR   A 1 424 ? 161.930 116.034 130.030 1.00 58.03  ? 449 THR   A OG1 1 
ATOM   3411 C CG2 . THR   A 1 424 ? 161.548 114.231 131.578 1.00 61.48  ? 449 THR   A CG2 1 
ATOM   3412 N N   . CYS   A 1 425 ? 158.080 113.761 130.224 1.00 62.60  ? 450 CYS   A N   1 
ATOM   3413 C CA  . CYS   A 1 425 ? 157.055 112.834 130.692 1.00 62.29  ? 450 CYS   A CA  1 
ATOM   3414 C C   . CYS   A 1 425 ? 156.788 111.745 129.660 1.00 61.67  ? 450 CYS   A C   1 
ATOM   3415 O O   . CYS   A 1 425 ? 156.704 110.555 129.999 1.00 65.89  ? 450 CYS   A O   1 
ATOM   3416 C CB  . CYS   A 1 425 ? 155.773 113.599 131.000 1.00 69.25  ? 450 CYS   A CB  1 
ATOM   3417 S SG  . CYS   A 1 425 ? 154.385 112.576 131.500 1.00 98.51  ? 450 CYS   A SG  1 
ATOM   3418 N N   . LEU   A 1 426 ? 156.662 112.133 128.390 1.00 61.21  ? 451 LEU   A N   1 
ATOM   3419 C CA  . LEU   A 1 426 ? 156.462 111.150 127.334 1.00 60.57  ? 451 LEU   A CA  1 
ATOM   3420 C C   . LEU   A 1 426 ? 157.660 110.221 127.224 1.00 59.28  ? 451 LEU   A C   1 
ATOM   3421 O O   . LEU   A 1 426 ? 157.504 109.023 126.969 1.00 66.38  ? 451 LEU   A O   1 
ATOM   3422 C CB  . LEU   A 1 426 ? 156.205 111.850 126.001 1.00 59.49  ? 451 LEU   A CB  1 
ATOM   3423 C CG  . LEU   A 1 426 ? 154.843 112.519 125.816 1.00 57.80  ? 451 LEU   A CG  1 
ATOM   3424 C CD1 . LEU   A 1 426 ? 154.844 113.368 124.563 1.00 61.16  ? 451 LEU   A CD1 1 
ATOM   3425 C CD2 . LEU   A 1 426 ? 153.733 111.490 125.752 1.00 60.08  ? 451 LEU   A CD2 1 
ATOM   3426 N N   . SER   A 1 427 ? 158.867 110.754 127.416 1.00 56.61  ? 452 SER   A N   1 
ATOM   3427 C CA  . SER   A 1 427 ? 160.058 109.919 127.337 1.00 61.60  ? 452 SER   A CA  1 
ATOM   3428 C C   . SER   A 1 427 ? 160.043 108.842 128.410 1.00 67.95  ? 452 SER   A C   1 
ATOM   3429 O O   . SER   A 1 427 ? 160.410 107.692 128.148 1.00 68.03  ? 452 SER   A O   1 
ATOM   3430 C CB  . SER   A 1 427 ? 161.312 110.778 127.466 1.00 64.93  ? 452 SER   A CB  1 
ATOM   3431 O OG  . SER   A 1 427 ? 162.473 109.969 127.488 1.00 68.83  ? 452 SER   A OG  1 
ATOM   3432 N N   . ARG   A 1 428 ? 159.618 109.191 129.626 1.00 70.21  ? 453 ARG   A N   1 
ATOM   3433 C CA  . ARG   A 1 428 ? 159.574 108.179 130.677 1.00 65.39  ? 453 ARG   A CA  1 
ATOM   3434 C C   . ARG   A 1 428 ? 158.391 107.227 130.538 1.00 63.87  ? 453 ARG   A C   1 
ATOM   3435 O O   . ARG   A 1 428 ? 158.478 106.095 131.025 1.00 67.87  ? 453 ARG   A O   1 
ATOM   3436 C CB  . ARG   A 1 428 ? 159.551 108.825 132.067 1.00 68.89  ? 453 ARG   A CB  1 
ATOM   3437 C CG  . ARG   A 1 428 ? 158.305 109.628 132.413 1.00 77.54  ? 453 ARG   A CG  1 
ATOM   3438 C CD  . ARG   A 1 428 ? 158.285 110.016 133.882 1.00 82.62  ? 453 ARG   A CD  1 
ATOM   3439 N NE  . ARG   A 1 428 ? 156.958 110.437 134.315 1.00 88.49  ? 453 ARG   A NE  1 
ATOM   3440 C CZ  . ARG   A 1 428 ? 156.641 110.795 135.552 1.00 98.46  ? 453 ARG   A CZ  1 
ATOM   3441 N NH1 . ARG   A 1 428 ? 157.539 110.807 136.527 1.00 99.85  ? 453 ARG   A NH1 1 
ATOM   3442 N NH2 . ARG   A 1 428 ? 155.389 111.153 135.822 1.00 94.88  ? 453 ARG   A NH2 1 
ATOM   3443 N N   . LEU   A 1 429 ? 157.298 107.643 129.892 1.00 60.52  ? 454 LEU   A N   1 
ATOM   3444 C CA  . LEU   A 1 429 ? 156.093 106.817 129.841 1.00 59.74  ? 454 LEU   A CA  1 
ATOM   3445 C C   . LEU   A 1 429 ? 155.991 105.929 128.608 1.00 63.50  ? 454 LEU   A C   1 
ATOM   3446 O O   . LEU   A 1 429 ? 155.395 104.851 128.694 1.00 69.40  ? 454 LEU   A O   1 
ATOM   3447 C CB  . LEU   A 1 429 ? 154.837 107.693 129.900 1.00 59.60  ? 454 LEU   A CB  1 
ATOM   3448 C CG  . LEU   A 1 429 ? 154.371 108.215 131.259 1.00 69.17  ? 454 LEU   A CG  1 
ATOM   3449 C CD1 . LEU   A 1 429 ? 153.200 109.154 131.065 1.00 70.67  ? 454 LEU   A CD1 1 
ATOM   3450 C CD2 . LEU   A 1 429 ? 153.985 107.086 132.204 1.00 73.91  ? 454 LEU   A CD2 1 
ATOM   3451 N N   . LEU   A 1 430 ? 156.532 106.345 127.465 1.00 63.51  ? 455 LEU   A N   1 
ATOM   3452 C CA  . LEU   A 1 430 ? 156.392 105.547 126.248 1.00 61.78  ? 455 LEU   A CA  1 
ATOM   3453 C C   . LEU   A 1 430 ? 156.990 104.144 126.334 1.00 65.69  ? 455 LEU   A C   1 
ATOM   3454 O O   . LEU   A 1 430 ? 156.451 103.245 125.664 1.00 73.99  ? 455 LEU   A O   1 
ATOM   3455 C CB  . LEU   A 1 430 ? 156.991 106.309 125.059 1.00 62.40  ? 455 LEU   A CB  1 
ATOM   3456 C CG  . LEU   A 1 430 ? 156.177 107.482 124.496 1.00 61.07  ? 455 LEU   A CG  1 
ATOM   3457 C CD1 . LEU   A 1 430 ? 156.982 108.213 123.435 1.00 66.46  ? 455 LEU   A CD1 1 
ATOM   3458 C CD2 . LEU   A 1 430 ? 154.846 107.036 123.924 1.00 57.76  ? 455 LEU   A CD2 1 
ATOM   3459 N N   . PRO   A 1 431 ? 158.073 103.878 127.076 1.00 62.09  ? 456 PRO   A N   1 
ATOM   3460 C CA  . PRO   A 1 431 ? 158.557 102.488 127.181 1.00 64.46  ? 456 PRO   A CA  1 
ATOM   3461 C C   . PRO   A 1 431 ? 157.539 101.493 127.711 1.00 70.89  ? 456 PRO   A C   1 
ATOM   3462 O O   . PRO   A 1 431 ? 157.723 100.287 127.513 1.00 73.49  ? 456 PRO   A O   1 
ATOM   3463 C CB  . PRO   A 1 431 ? 159.756 102.614 128.125 1.00 66.46  ? 456 PRO   A CB  1 
ATOM   3464 C CG  . PRO   A 1 431 ? 160.293 103.943 127.828 1.00 70.19  ? 456 PRO   A CG  1 
ATOM   3465 C CD  . PRO   A 1 431 ? 159.106 104.824 127.538 1.00 66.45  ? 456 PRO   A CD  1 
ATOM   3466 N N   . LYS   A 1 432 ? 156.471 101.946 128.365 1.00 71.25  ? 457 LYS   A N   1 
ATOM   3467 C CA  . LYS   A 1 432 ? 155.395 101.038 128.733 1.00 68.15  ? 457 LYS   A CA  1 
ATOM   3468 C C   . LYS   A 1 432 ? 154.629 100.526 127.518 1.00 70.93  ? 457 LYS   A C   1 
ATOM   3469 O O   . LYS   A 1 432 ? 153.950 99.500  127.623 1.00 76.91  ? 457 LYS   A O   1 
ATOM   3470 C CB  . LYS   A 1 432 ? 154.443 101.742 129.699 1.00 72.73  ? 457 LYS   A CB  1 
ATOM   3471 C CG  . LYS   A 1 432 ? 153.315 100.871 130.222 1.00 77.71  ? 457 LYS   A CG  1 
ATOM   3472 C CD  . LYS   A 1 432 ? 152.602 101.513 131.406 1.00 81.47  ? 457 LYS   A CD  1 
ATOM   3473 C CE  . LYS   A 1 432 ? 151.874 102.792 131.017 1.00 81.33  ? 457 LYS   A CE  1 
ATOM   3474 N NZ  . LYS   A 1 432 ? 151.093 103.357 132.152 1.00 81.63  ? 457 LYS   A NZ  1 
ATOM   3475 N N   . TYR   A 1 433 ? 154.732 101.206 126.370 1.00 72.17  ? 458 TYR   A N   1 
ATOM   3476 C CA  . TYR   A 1 433 ? 153.998 100.864 125.157 1.00 68.99  ? 458 TYR   A CA  1 
ATOM   3477 C C   . TYR   A 1 433 ? 154.920 100.369 124.044 1.00 73.31  ? 458 TYR   A C   1 
ATOM   3478 O O   . TYR   A 1 433 ? 154.641 100.579 122.862 1.00 75.23  ? 458 TYR   A O   1 
ATOM   3479 C CB  . TYR   A 1 433 ? 153.191 102.066 124.676 1.00 64.30  ? 458 TYR   A CB  1 
ATOM   3480 C CG  . TYR   A 1 433 ? 152.202 102.590 125.688 1.00 63.12  ? 458 TYR   A CG  1 
ATOM   3481 C CD1 . TYR   A 1 433 ? 152.564 103.564 126.603 1.00 65.02  ? 458 TYR   A CD1 1 
ATOM   3482 C CD2 . TYR   A 1 433 ? 150.902 102.115 125.723 1.00 65.68  ? 458 TYR   A CD2 1 
ATOM   3483 C CE1 . TYR   A 1 433 ? 151.663 104.044 127.526 1.00 67.54  ? 458 TYR   A CE1 1 
ATOM   3484 C CE2 . TYR   A 1 433 ? 149.996 102.590 126.642 1.00 62.73  ? 458 TYR   A CE2 1 
ATOM   3485 C CZ  . TYR   A 1 433 ? 150.380 103.554 127.540 1.00 65.47  ? 458 TYR   A CZ  1 
ATOM   3486 O OH  . TYR   A 1 433 ? 149.476 104.028 128.458 1.00 69.58  ? 458 TYR   A OH  1 
ATOM   3487 N N   . ASN   A 1 434 ? 156.024 99.716  124.409 1.00 75.22  ? 459 ASN   A N   1 
ATOM   3488 C CA  . ASN   A 1 434 ? 156.938 99.086  123.452 1.00 77.78  ? 459 ASN   A CA  1 
ATOM   3489 C C   . ASN   A 1 434 ? 157.584 100.108 122.515 1.00 81.67  ? 459 ASN   A C   1 
ATOM   3490 O O   . ASN   A 1 434 ? 157.623 99.912  121.300 1.00 83.98  ? 459 ASN   A O   1 
ATOM   3491 C CB  . ASN   A 1 434 ? 156.233 97.989  122.650 1.00 85.04  ? 459 ASN   A CB  1 
ATOM   3492 C CG  . ASN   A 1 434 ? 155.759 96.845  123.522 1.00 104.86 ? 459 ASN   A CG  1 
ATOM   3493 O OD1 . ASN   A 1 434 ? 156.391 96.510  124.523 1.00 105.13 ? 459 ASN   A OD1 1 
ATOM   3494 N ND2 . ASN   A 1 434 ? 154.640 96.237  123.145 1.00 116.36 ? 459 ASN   A ND2 1 
ATOM   3495 N N   . VAL   A 1 435 ? 158.092 101.202 123.081 1.00 77.32  ? 460 VAL   A N   1 
ATOM   3496 C CA  . VAL   A 1 435 ? 158.902 102.180 122.361 1.00 72.71  ? 460 VAL   A CA  1 
ATOM   3497 C C   . VAL   A 1 435 ? 160.193 102.389 123.139 1.00 76.41  ? 460 VAL   A C   1 
ATOM   3498 O O   . VAL   A 1 435 ? 160.158 102.671 124.341 1.00 80.27  ? 460 VAL   A O   1 
ATOM   3499 C CB  . VAL   A 1 435 ? 158.156 103.514 122.173 1.00 71.89  ? 460 VAL   A CB  1 
ATOM   3500 C CG1 . VAL   A 1 435 ? 159.077 104.559 121.566 1.00 73.64  ? 460 VAL   A CG1 1 
ATOM   3501 C CG2 . VAL   A 1 435 ? 156.924 103.320 121.304 1.00 73.89  ? 460 VAL   A CG2 1 
ATOM   3502 N N   . THR   A 1 436 ? 161.326 102.284 122.455 1.00 82.54  ? 461 THR   A N   1 
ATOM   3503 C CA  . THR   A 1 436 ? 162.621 102.464 123.100 1.00 84.91  ? 461 THR   A CA  1 
ATOM   3504 C C   . THR   A 1 436 ? 162.867 103.961 123.282 1.00 85.12  ? 461 THR   A C   1 
ATOM   3505 O O   . THR   A 1 436 ? 161.948 104.774 123.156 1.00 88.15  ? 461 THR   A O   1 
ATOM   3506 C CB  . THR   A 1 436 ? 163.721 101.786 122.290 1.00 92.32  ? 461 THR   A CB  1 
ATOM   3507 O OG1 . THR   A 1 436 ? 163.912 102.482 121.052 1.00 97.25  ? 461 THR   A OG1 1 
ATOM   3508 C CG2 . THR   A 1 436 ? 163.351 100.337 122.007 1.00 94.13  ? 461 THR   A CG2 1 
ATOM   3509 N N   . GLU   A 1 437 ? 164.109 104.340 123.617 1.00 83.40  ? 462 GLU   A N   1 
ATOM   3510 C CA  . GLU   A 1 437 ? 164.454 105.734 123.886 1.00 81.73  ? 462 GLU   A CA  1 
ATOM   3511 C C   . GLU   A 1 437 ? 164.089 106.598 122.681 1.00 75.91  ? 462 GLU   A C   1 
ATOM   3512 O O   . GLU   A 1 437 ? 164.788 106.541 121.663 1.00 80.29  ? 462 GLU   A O   1 
ATOM   3513 C CB  . GLU   A 1 437 ? 165.946 105.865 124.189 1.00 88.89  ? 462 GLU   A CB  1 
ATOM   3514 C CG  . GLU   A 1 437 ? 166.394 105.103 125.426 1.00 99.35  ? 462 GLU   A CG  1 
ATOM   3515 C CD  . GLU   A 1 437 ? 167.872 105.273 125.715 1.00 106.74 ? 462 GLU   A CD  1 
ATOM   3516 O OE1 . GLU   A 1 437 ? 168.551 105.990 124.950 1.00 105.88 ? 462 GLU   A OE1 1 
ATOM   3517 O OE2 . GLU   A 1 437 ? 168.356 104.688 126.707 1.00 107.06 ? 462 GLU   A OE2 1 
ATOM   3518 N N   . PRO   A 1 438 ? 163.030 107.407 122.740 1.00 67.30  ? 463 PRO   A N   1 
ATOM   3519 C CA  . PRO   A 1 438 ? 162.521 108.043 121.526 1.00 69.72  ? 463 PRO   A CA  1 
ATOM   3520 C C   . PRO   A 1 438 ? 163.114 109.427 121.283 1.00 66.88  ? 463 PRO   A C   1 
ATOM   3521 O O   . PRO   A 1 438 ? 163.764 110.020 122.145 1.00 68.89  ? 463 PRO   A O   1 
ATOM   3522 C CB  . PRO   A 1 438 ? 161.021 108.141 121.814 1.00 68.97  ? 463 PRO   A CB  1 
ATOM   3523 C CG  . PRO   A 1 438 ? 160.971 108.425 123.257 1.00 68.31  ? 463 PRO   A CG  1 
ATOM   3524 C CD  . PRO   A 1 438 ? 162.164 107.740 123.888 1.00 67.25  ? 463 PRO   A CD  1 
ATOM   3525 N N   . GLN   A 1 439 ? 162.879 109.923 120.071 1.00 63.66  ? 464 GLN   A N   1 
ATOM   3526 C CA  . GLN   A 1 439 ? 163.094 111.321 119.719 1.00 63.12  ? 464 GLN   A CA  1 
ATOM   3527 C C   . GLN   A 1 439 ? 161.739 111.896 119.337 1.00 66.38  ? 464 GLN   A C   1 
ATOM   3528 O O   . GLN   A 1 439 ? 161.107 111.404 118.397 1.00 73.79  ? 464 GLN   A O   1 
ATOM   3529 C CB  . GLN   A 1 439 ? 164.082 111.463 118.560 1.00 64.41  ? 464 GLN   A CB  1 
ATOM   3530 C CG  . GLN   A 1 439 ? 165.319 110.589 118.659 1.00 66.03  ? 464 GLN   A CG  1 
ATOM   3531 C CD  . GLN   A 1 439 ? 166.258 110.789 117.491 1.00 67.12  ? 464 GLN   A CD  1 
ATOM   3532 O OE1 . GLN   A 1 439 ? 166.184 111.794 116.788 1.00 71.39  ? 464 GLN   A OE1 1 
ATOM   3533 N NE2 . GLN   A 1 439 ? 167.144 109.827 117.272 1.00 66.14  ? 464 GLN   A NE2 1 
ATOM   3534 N N   . ILE   A 1 440 ? 161.304 112.936 120.046 1.00 62.48  ? 465 ILE   A N   1 
ATOM   3535 C CA  . ILE   A 1 440 ? 159.951 113.473 119.926 1.00 57.81  ? 465 ILE   A CA  1 
ATOM   3536 C C   . ILE   A 1 440 ? 160.034 114.860 119.304 1.00 64.80  ? 465 ILE   A C   1 
ATOM   3537 O O   . ILE   A 1 440 ? 160.819 115.704 119.752 1.00 68.37  ? 465 ILE   A O   1 
ATOM   3538 C CB  . ILE   A 1 440 ? 159.229 113.512 121.287 1.00 56.59  ? 465 ILE   A CB  1 
ATOM   3539 C CG1 . ILE   A 1 440 ? 159.268 112.128 121.953 1.00 64.93  ? 465 ILE   A CG1 1 
ATOM   3540 C CG2 . ILE   A 1 440 ? 157.766 113.964 121.117 1.00 61.54  ? 465 ILE   A CG2 1 
ATOM   3541 C CD1 . ILE   A 1 440 ? 158.615 112.058 123.320 1.00 70.02  ? 465 ILE   A CD1 1 
ATOM   3542 N N   . TYR   A 1 441 ? 159.218 115.089 118.275 1.00 64.63  ? 466 TYR   A N   1 
ATOM   3543 C CA  . TYR   A 1 441 ? 159.116 116.359 117.576 1.00 59.59  ? 466 TYR   A CA  1 
ATOM   3544 C C   . TYR   A 1 441 ? 157.694 116.893 117.688 1.00 62.88  ? 466 TYR   A C   1 
ATOM   3545 O O   . TYR   A 1 441 ? 156.726 116.125 117.697 1.00 71.53  ? 466 TYR   A O   1 
ATOM   3546 C CB  . TYR   A 1 441 ? 159.476 116.217 116.098 1.00 59.61  ? 466 TYR   A CB  1 
ATOM   3547 C CG  . TYR   A 1 441 ? 160.815 115.576 115.829 1.00 61.57  ? 466 TYR   A CG  1 
ATOM   3548 C CD1 . TYR   A 1 441 ? 160.946 114.203 115.771 1.00 59.39  ? 466 TYR   A CD1 1 
ATOM   3549 C CD2 . TYR   A 1 441 ? 161.942 116.347 115.606 1.00 66.99  ? 466 TYR   A CD2 1 
ATOM   3550 C CE1 . TYR   A 1 441 ? 162.158 113.615 115.516 1.00 62.32  ? 466 TYR   A CE1 1 
ATOM   3551 C CE2 . TYR   A 1 441 ? 163.162 115.764 115.350 1.00 66.61  ? 466 TYR   A CE2 1 
ATOM   3552 C CZ  . TYR   A 1 441 ? 163.263 114.397 115.305 1.00 65.15  ? 466 TYR   A CZ  1 
ATOM   3553 O OH  . TYR   A 1 441 ? 164.477 113.806 115.051 1.00 75.10  ? 466 TYR   A OH  1 
ATOM   3554 N N   . PHE   A 1 442 ? 157.581 118.221 117.749 1.00 59.73  ? 467 PHE   A N   1 
ATOM   3555 C CA  . PHE   A 1 442 ? 156.310 118.917 117.896 1.00 58.52  ? 467 PHE   A CA  1 
ATOM   3556 C C   . PHE   A 1 442 ? 156.124 119.901 116.750 1.00 60.91  ? 467 PHE   A C   1 
ATOM   3557 O O   . PHE   A 1 442 ? 157.079 120.553 116.322 1.00 63.26  ? 467 PHE   A O   1 
ATOM   3558 C CB  . PHE   A 1 442 ? 156.242 119.669 119.230 1.00 61.80  ? 467 PHE   A CB  1 
ATOM   3559 C CG  . PHE   A 1 442 ? 156.096 118.776 120.428 1.00 58.82  ? 467 PHE   A CG  1 
ATOM   3560 C CD1 . PHE   A 1 442 ? 157.186 118.114 120.953 1.00 60.59  ? 467 PHE   A CD1 1 
ATOM   3561 C CD2 . PHE   A 1 442 ? 154.871 118.617 121.039 1.00 62.19  ? 467 PHE   A CD2 1 
ATOM   3562 C CE1 . PHE   A 1 442 ? 157.052 117.301 122.054 1.00 64.94  ? 467 PHE   A CE1 1 
ATOM   3563 C CE2 . PHE   A 1 442 ? 154.733 117.804 122.139 1.00 63.81  ? 467 PHE   A CE2 1 
ATOM   3564 C CZ  . PHE   A 1 442 ? 155.825 117.146 122.646 1.00 66.00  ? 467 PHE   A CZ  1 
ATOM   3565 N N   . ASP   A 1 443 ? 154.889 120.004 116.257 1.00 61.65  ? 468 ASP   A N   1 
ATOM   3566 C CA  . ASP   A 1 443 ? 154.528 120.960 115.213 1.00 58.07  ? 468 ASP   A CA  1 
ATOM   3567 C C   . ASP   A 1 443 ? 153.172 121.543 115.581 1.00 56.93  ? 468 ASP   A C   1 
ATOM   3568 O O   . ASP   A 1 443 ? 152.154 120.850 115.485 1.00 60.77  ? 468 ASP   A O   1 
ATOM   3569 C CB  . ASP   A 1 443 ? 154.485 120.296 113.839 1.00 57.68  ? 468 ASP   A CB  1 
ATOM   3570 C CG  . ASP   A 1 443 ? 154.237 121.284 112.719 1.00 65.85  ? 468 ASP   A CG  1 
ATOM   3571 O OD1 . ASP   A 1 443 ? 154.250 122.506 112.979 1.00 68.14  ? 468 ASP   A OD1 1 
ATOM   3572 O OD2 . ASP   A 1 443 ? 154.032 120.838 111.571 1.00 68.11  ? 468 ASP   A OD2 1 
ATOM   3573 N N   . ILE   A 1 444 ? 153.160 122.805 116.005 1.00 54.36  ? 469 ILE   A N   1 
ATOM   3574 C CA  . ILE   A 1 444 ? 151.978 123.450 116.564 1.00 54.40  ? 469 ILE   A CA  1 
ATOM   3575 C C   . ILE   A 1 444 ? 151.729 124.745 115.805 1.00 56.42  ? 469 ILE   A C   1 
ATOM   3576 O O   . ILE   A 1 444 ? 152.655 125.537 115.604 1.00 60.92  ? 469 ILE   A O   1 
ATOM   3577 C CB  . ILE   A 1 444 ? 152.143 123.728 118.070 1.00 58.04  ? 469 ILE   A CB  1 
ATOM   3578 C CG1 . ILE   A 1 444 ? 152.277 122.414 118.850 1.00 59.34  ? 469 ILE   A CG1 1 
ATOM   3579 C CG2 . ILE   A 1 444 ? 150.963 124.540 118.586 1.00 61.86  ? 469 ILE   A CG2 1 
ATOM   3580 C CD1 . ILE   A 1 444 ? 152.837 122.573 120.245 1.00 66.04  ? 469 ILE   A CD1 1 
ATOM   3581 N N   . TRP   A 1 445 ? 150.481 124.957 115.393 1.00 54.07  ? 470 TRP   A N   1 
ATOM   3582 C CA  . TRP   A 1 445 ? 150.054 126.158 114.686 1.00 52.08  ? 470 TRP   A CA  1 
ATOM   3583 C C   . TRP   A 1 445 ? 149.136 126.968 115.590 1.00 56.49  ? 470 TRP   A C   1 
ATOM   3584 O O   . TRP   A 1 445 ? 148.215 126.414 116.198 1.00 62.66  ? 470 TRP   A O   1 
ATOM   3585 C CB  . TRP   A 1 445 ? 149.332 125.799 113.386 1.00 50.30  ? 470 TRP   A CB  1 
ATOM   3586 C CG  . TRP   A 1 445 ? 150.175 125.044 112.407 1.00 52.75  ? 470 TRP   A CG  1 
ATOM   3587 C CD1 . TRP   A 1 445 ? 150.473 123.720 112.439 1.00 54.10  ? 470 TRP   A CD1 1 
ATOM   3588 C CD2 . TRP   A 1 445 ? 150.817 125.571 111.243 1.00 52.74  ? 470 TRP   A CD2 1 
ATOM   3589 N NE1 . TRP   A 1 445 ? 151.267 123.386 111.374 1.00 52.28  ? 470 TRP   A NE1 1 
ATOM   3590 C CE2 . TRP   A 1 445 ? 151.492 124.507 110.623 1.00 51.38  ? 470 TRP   A CE2 1 
ATOM   3591 C CE3 . TRP   A 1 445 ? 150.891 126.841 110.668 1.00 58.63  ? 470 TRP   A CE3 1 
ATOM   3592 C CZ2 . TRP   A 1 445 ? 152.232 124.671 109.459 1.00 59.42  ? 470 TRP   A CZ2 1 
ATOM   3593 C CZ3 . TRP   A 1 445 ? 151.625 127.000 109.512 1.00 59.24  ? 470 TRP   A CZ3 1 
ATOM   3594 C CH2 . TRP   A 1 445 ? 152.284 125.922 108.919 1.00 59.96  ? 470 TRP   A CH2 1 
ATOM   3595 N N   . VAL   A 1 446 ? 149.387 128.272 115.679 1.00 54.90  ? 471 VAL   A N   1 
ATOM   3596 C CA  . VAL   A 1 446 ? 148.611 129.154 116.545 1.00 54.76  ? 471 VAL   A CA  1 
ATOM   3597 C C   . VAL   A 1 446 ? 148.652 130.562 115.971 1.00 57.93  ? 471 VAL   A C   1 
ATOM   3598 O O   . VAL   A 1 446 ? 149.665 130.986 115.409 1.00 62.53  ? 471 VAL   A O   1 
ATOM   3599 C CB  . VAL   A 1 446 ? 149.140 129.116 117.997 1.00 62.32  ? 471 VAL   A CB  1 
ATOM   3600 C CG1 . VAL   A 1 446 ? 150.657 129.282 118.035 1.00 64.10  ? 471 VAL   A CG1 1 
ATOM   3601 C CG2 . VAL   A 1 446 ? 148.454 130.170 118.857 1.00 65.55  ? 471 VAL   A CG2 1 
ATOM   3602 N N   . SER   A 1 447 ? 147.539 131.283 116.111 1.00 58.15  ? 472 SER   A N   1 
ATOM   3603 C CA  . SER   A 1 447 ? 147.427 132.676 115.700 1.00 60.26  ? 472 SER   A CA  1 
ATOM   3604 C C   . SER   A 1 447 ? 146.866 133.499 116.847 1.00 61.92  ? 472 SER   A C   1 
ATOM   3605 O O   . SER   A 1 447 ? 145.923 133.070 117.523 1.00 67.67  ? 472 SER   A O   1 
ATOM   3606 C CB  . SER   A 1 447 ? 146.526 132.824 114.478 1.00 64.88  ? 472 SER   A CB  1 
ATOM   3607 O OG  . SER   A 1 447 ? 145.204 132.409 114.771 1.00 68.20  ? 472 SER   A OG  1 
ATOM   3608 N N   . ILE   A 1 448 ? 147.435 134.689 117.044 1.00 60.08  ? 473 ILE   A N   1 
ATOM   3609 C CA  . ILE   A 1 448 ? 147.051 135.600 118.119 1.00 61.38  ? 473 ILE   A CA  1 
ATOM   3610 C C   . ILE   A 1 448 ? 146.322 136.782 117.497 1.00 65.15  ? 473 ILE   A C   1 
ATOM   3611 O O   . ILE   A 1 448 ? 146.860 137.455 116.609 1.00 69.36  ? 473 ILE   A O   1 
ATOM   3612 C CB  . ILE   A 1 448 ? 148.265 136.069 118.941 1.00 59.99  ? 473 ILE   A CB  1 
ATOM   3613 C CG1 . ILE   A 1 448 ? 148.924 134.858 119.615 1.00 64.52  ? 473 ILE   A CG1 1 
ATOM   3614 C CG2 . ILE   A 1 448 ? 147.834 137.145 119.975 1.00 64.50  ? 473 ILE   A CG2 1 
ATOM   3615 C CD1 . ILE   A 1 448 ? 150.127 135.161 120.494 1.00 66.74  ? 473 ILE   A CD1 1 
ATOM   3616 N N   . ASN   A 1 449 ? 145.107 137.042 117.981 1.00 64.63  ? 474 ASN   A N   1 
ATOM   3617 C CA  . ASN   A 1 449 ? 144.305 138.194 117.566 1.00 60.65  ? 474 ASN   A CA  1 
ATOM   3618 C C   . ASN   A 1 449 ? 144.088 138.208 116.054 1.00 64.24  ? 474 ASN   A C   1 
ATOM   3619 O O   . ASN   A 1 449 ? 144.242 139.232 115.388 1.00 68.15  ? 474 ASN   A O   1 
ATOM   3620 C CB  . ASN   A 1 449 ? 144.937 139.503 118.044 1.00 62.59  ? 474 ASN   A CB  1 
ATOM   3621 C CG  . ASN   A 1 449 ? 144.870 139.665 119.548 1.00 70.92  ? 474 ASN   A CG  1 
ATOM   3622 O OD1 . ASN   A 1 449 ? 143.972 139.137 120.199 1.00 70.36  ? 474 ASN   A OD1 1 
ATOM   3623 N ND2 . ASN   A 1 449 ? 145.819 140.403 120.107 1.00 74.92  ? 474 ASN   A ND2 1 
ATOM   3624 N N   . ASP   A 1 450 ? 143.723 137.046 115.517 1.00 66.67  ? 475 ASP   A N   1 
ATOM   3625 C CA  . ASP   A 1 450 ? 143.271 136.908 114.135 1.00 67.69  ? 475 ASP   A CA  1 
ATOM   3626 C C   . ASP   A 1 450 ? 144.343 137.370 113.146 1.00 62.38  ? 475 ASP   A C   1 
ATOM   3627 O O   . ASP   A 1 450 ? 144.129 138.270 112.335 1.00 67.02  ? 475 ASP   A O   1 
ATOM   3628 C CB  . ASP   A 1 450 ? 141.962 137.676 113.929 1.00 71.19  ? 475 ASP   A CB  1 
ATOM   3629 C CG  . ASP   A 1 450 ? 141.293 137.352 112.604 1.00 82.09  ? 475 ASP   A CG  1 
ATOM   3630 O OD1 . ASP   A 1 450 ? 141.794 136.471 111.874 1.00 76.77  ? 475 ASP   A OD1 1 
ATOM   3631 O OD2 . ASP   A 1 450 ? 140.261 137.982 112.293 1.00 90.57  ? 475 ASP   A OD2 1 
ATOM   3632 N N   . ARG   A 1 451 ? 145.505 136.731 113.229 1.00 59.16  ? 476 ARG   A N   1 
ATOM   3633 C CA  . ARG   A 1 451 ? 146.597 136.897 112.281 1.00 60.06  ? 476 ARG   A CA  1 
ATOM   3634 C C   . ARG   A 1 451 ? 146.726 135.625 111.447 1.00 65.03  ? 476 ARG   A C   1 
ATOM   3635 O O   . ARG   A 1 451 ? 145.943 134.682 111.583 1.00 65.82  ? 476 ARG   A O   1 
ATOM   3636 C CB  . ARG   A 1 451 ? 147.908 137.207 113.009 1.00 58.46  ? 476 ARG   A CB  1 
ATOM   3637 C CG  . ARG   A 1 451 ? 147.919 138.511 113.789 1.00 62.48  ? 476 ARG   A CG  1 
ATOM   3638 C CD  . ARG   A 1 451 ? 149.195 138.653 114.609 1.00 63.30  ? 476 ARG   A CD  1 
ATOM   3639 N NE  . ARG   A 1 451 ? 149.016 139.512 115.775 1.00 67.69  ? 476 ARG   A NE  1 
ATOM   3640 C CZ  . ARG   A 1 451 ? 149.147 140.832 115.786 1.00 75.48  ? 476 ARG   A CZ  1 
ATOM   3641 N NH1 . ARG   A 1 451 ? 149.448 141.515 114.693 1.00 78.95  ? 476 ARG   A NH1 1 
ATOM   3642 N NH2 . ARG   A 1 451 ? 148.966 141.488 116.928 1.00 76.72  ? 476 ARG   A NH2 1 
ATOM   3643 N N   . PHE   A 1 452 ? 147.725 135.606 110.569 1.00 65.93  ? 477 PHE   A N   1 
ATOM   3644 C CA  . PHE   A 1 452 ? 148.067 134.380 109.866 1.00 58.90  ? 477 PHE   A CA  1 
ATOM   3645 C C   . PHE   A 1 452 ? 148.516 133.322 110.863 1.00 61.25  ? 477 PHE   A C   1 
ATOM   3646 O O   . PHE   A 1 452 ? 149.207 133.621 111.840 1.00 66.79  ? 477 PHE   A O   1 
ATOM   3647 C CB  . PHE   A 1 452 ? 149.180 134.634 108.852 1.00 59.36  ? 477 PHE   A CB  1 
ATOM   3648 C CG  . PHE   A 1 452 ? 148.748 135.418 107.650 1.00 59.35  ? 477 PHE   A CG  1 
ATOM   3649 C CD1 . PHE   A 1 452 ? 148.118 134.794 106.592 1.00 66.32  ? 477 PHE   A CD1 1 
ATOM   3650 C CD2 . PHE   A 1 452 ? 148.998 136.768 107.564 1.00 62.28  ? 477 PHE   A CD2 1 
ATOM   3651 C CE1 . PHE   A 1 452 ? 147.731 135.507 105.483 1.00 68.02  ? 477 PHE   A CE1 1 
ATOM   3652 C CE2 . PHE   A 1 452 ? 148.613 137.484 106.456 1.00 68.19  ? 477 PHE   A CE2 1 
ATOM   3653 C CZ  . PHE   A 1 452 ? 147.978 136.851 105.414 1.00 66.37  ? 477 PHE   A CZ  1 
ATOM   3654 N N   . GLN   A 1 453 ? 148.121 132.078 110.616 1.00 58.77  ? 478 GLN   A N   1 
ATOM   3655 C CA  . GLN   A 1 453 ? 148.518 130.970 111.474 1.00 58.99  ? 478 GLN   A CA  1 
ATOM   3656 C C   . GLN   A 1 453 ? 149.926 130.526 111.100 1.00 61.76  ? 478 GLN   A C   1 
ATOM   3657 O O   . GLN   A 1 453 ? 150.181 130.170 109.946 1.00 68.36  ? 478 GLN   A O   1 
ATOM   3658 C CB  . GLN   A 1 453 ? 147.535 129.812 111.336 1.00 56.15  ? 478 GLN   A CB  1 
ATOM   3659 C CG  . GLN   A 1 453 ? 146.086 130.202 111.562 1.00 56.50  ? 478 GLN   A CG  1 
ATOM   3660 C CD  . GLN   A 1 453 ? 145.351 129.273 112.506 1.00 59.77  ? 478 GLN   A CD  1 
ATOM   3661 O OE1 . GLN   A 1 453 ? 145.907 128.800 113.495 1.00 59.46  ? 478 GLN   A OE1 1 
ATOM   3662 N NE2 . GLN   A 1 453 ? 144.082 129.019 112.210 1.00 63.76  ? 478 GLN   A NE2 1 
ATOM   3663 N N   . GLN   A 1 454 ? 150.833 130.547 112.074 1.00 59.90  ? 479 GLN   A N   1 
ATOM   3664 C CA  . GLN   A 1 454 ? 152.231 130.208 111.853 1.00 59.77  ? 479 GLN   A CA  1 
ATOM   3665 C C   . GLN   A 1 454 ? 152.716 129.299 112.970 1.00 58.66  ? 479 GLN   A C   1 
ATOM   3666 O O   . GLN   A 1 454 ? 152.119 129.226 114.045 1.00 60.05  ? 479 GLN   A O   1 
ATOM   3667 C CB  . GLN   A 1 454 ? 153.114 131.457 111.787 1.00 60.76  ? 479 GLN   A CB  1 
ATOM   3668 C CG  . GLN   A 1 454 ? 152.792 132.498 112.850 1.00 58.83  ? 479 GLN   A CG  1 
ATOM   3669 C CD  . GLN   A 1 454 ? 154.001 133.292 113.319 1.00 64.41  ? 479 GLN   A CD  1 
ATOM   3670 O OE1 . GLN   A 1 454 ? 154.085 133.659 114.487 1.00 68.90  ? 479 GLN   A OE1 1 
ATOM   3671 N NE2 . GLN   A 1 454 ? 154.930 133.578 112.412 1.00 70.89  ? 479 GLN   A NE2 1 
ATOM   3672 N N   . ARG   A 1 455 ? 153.814 128.604 112.696 1.00 56.03  ? 480 ARG   A N   1 
ATOM   3673 C CA  . ARG   A 1 455 ? 154.403 127.716 113.683 1.00 55.94  ? 480 ARG   A CA  1 
ATOM   3674 C C   . ARG   A 1 455 ? 154.926 128.507 114.874 1.00 62.99  ? 480 ARG   A C   1 
ATOM   3675 O O   . ARG   A 1 455 ? 155.358 129.656 114.744 1.00 68.73  ? 480 ARG   A O   1 
ATOM   3676 C CB  . ARG   A 1 455 ? 155.539 126.907 113.065 1.00 59.53  ? 480 ARG   A CB  1 
ATOM   3677 C CG  . ARG   A 1 455 ? 155.099 125.905 112.020 1.00 61.16  ? 480 ARG   A CG  1 
ATOM   3678 C CD  . ARG   A 1 455 ? 156.232 124.964 111.665 1.00 63.27  ? 480 ARG   A CD  1 
ATOM   3679 N NE  . ARG   A 1 455 ? 155.819 123.914 110.740 1.00 63.08  ? 480 ARG   A NE  1 
ATOM   3680 C CZ  . ARG   A 1 455 ? 155.789 124.025 109.419 1.00 69.29  ? 480 ARG   A CZ  1 
ATOM   3681 N NH1 . ARG   A 1 455 ? 156.113 125.153 108.804 1.00 71.92  ? 480 ARG   A NH1 1 
ATOM   3682 N NH2 . ARG   A 1 455 ? 155.420 122.976 108.691 1.00 68.66  ? 480 ARG   A NH2 1 
ATOM   3683 N N   . ILE   A 1 456 ? 154.882 127.871 116.044 1.00 61.82  ? 481 ILE   A N   1 
ATOM   3684 C CA  . ILE   A 1 456 ? 155.387 128.462 117.273 1.00 59.64  ? 481 ILE   A CA  1 
ATOM   3685 C C   . ILE   A 1 456 ? 156.711 127.844 117.714 1.00 59.22  ? 481 ILE   A C   1 
ATOM   3686 O O   . ILE   A 1 456 ? 157.535 128.546 118.313 1.00 63.48  ? 481 ILE   A O   1 
ATOM   3687 C CB  . ILE   A 1 456 ? 154.335 128.377 118.401 1.00 62.01  ? 481 ILE   A CB  1 
ATOM   3688 C CG1 . ILE   A 1 456 ? 154.899 128.950 119.703 1.00 64.43  ? 481 ILE   A CG1 1 
ATOM   3689 C CG2 . ILE   A 1 456 ? 153.834 126.944 118.600 1.00 62.44  ? 481 ILE   A CG2 1 
ATOM   3690 C CD1 . ILE   A 1 456 ? 153.837 129.406 120.677 1.00 65.78  ? 481 ILE   A CD1 1 
ATOM   3691 N N   . PHE   A 1 457 ? 156.938 126.560 117.442 1.00 55.20  ? 482 PHE   A N   1 
ATOM   3692 C CA  . PHE   A 1 457 ? 158.193 125.885 117.737 1.00 54.10  ? 482 PHE   A CA  1 
ATOM   3693 C C   . PHE   A 1 457 ? 158.729 125.250 116.464 1.00 62.62  ? 482 PHE   A C   1 
ATOM   3694 O O   . PHE   A 1 457 ? 157.964 124.825 115.596 1.00 69.68  ? 482 PHE   A O   1 
ATOM   3695 C CB  . PHE   A 1 457 ? 158.024 124.811 118.814 1.00 55.95  ? 482 PHE   A CB  1 
ATOM   3696 C CG  . PHE   A 1 457 ? 157.373 125.307 120.068 1.00 55.39  ? 482 PHE   A CG  1 
ATOM   3697 C CD1 . PHE   A 1 457 ? 157.991 126.255 120.858 1.00 60.33  ? 482 PHE   A CD1 1 
ATOM   3698 C CD2 . PHE   A 1 457 ? 156.149 124.812 120.465 1.00 57.38  ? 482 PHE   A CD2 1 
ATOM   3699 C CE1 . PHE   A 1 457 ? 157.393 126.706 122.011 1.00 61.82  ? 482 PHE   A CE1 1 
ATOM   3700 C CE2 . PHE   A 1 457 ? 155.548 125.260 121.614 1.00 59.08  ? 482 PHE   A CE2 1 
ATOM   3701 C CZ  . PHE   A 1 457 ? 156.169 126.207 122.389 1.00 61.00  ? 482 PHE   A CZ  1 
ATOM   3702 N N   . ASP   A 1 458 ? 160.050 125.197 116.360 1.00 65.71  ? 483 ASP   A N   1 
ATOM   3703 C CA  . ASP   A 1 458 ? 160.685 124.628 115.180 1.00 62.66  ? 483 ASP   A CA  1 
ATOM   3704 C C   . ASP   A 1 458 ? 160.352 123.138 115.095 1.00 64.68  ? 483 ASP   A C   1 
ATOM   3705 O O   . ASP   A 1 458 ? 160.568 122.413 116.073 1.00 72.48  ? 483 ASP   A O   1 
ATOM   3706 C CB  . ASP   A 1 458 ? 162.195 124.833 115.258 1.00 61.40  ? 483 ASP   A CB  1 
ATOM   3707 C CG  . ASP   A 1 458 ? 162.887 124.633 113.926 1.00 70.91  ? 483 ASP   A CG  1 
ATOM   3708 O OD1 . ASP   A 1 458 ? 162.584 123.645 113.226 1.00 75.28  ? 483 ASP   A OD1 1 
ATOM   3709 O OD2 . ASP   A 1 458 ? 163.744 125.471 113.577 1.00 76.07  ? 483 ASP   A OD2 1 
ATOM   3710 N N   . PRO   A 1 459 ? 159.832 122.636 113.971 1.00 60.90  ? 484 PRO   A N   1 
ATOM   3711 C CA  . PRO   A 1 459 ? 159.446 121.223 113.906 1.00 61.68  ? 484 PRO   A CA  1 
ATOM   3712 C C   . PRO   A 1 459 ? 160.582 120.259 113.600 1.00 67.34  ? 484 PRO   A C   1 
ATOM   3713 O O   . PRO   A 1 459 ? 160.307 119.088 113.326 1.00 69.03  ? 484 PRO   A O   1 
ATOM   3714 C CB  . PRO   A 1 459 ? 158.414 121.218 112.772 1.00 65.19  ? 484 PRO   A CB  1 
ATOM   3715 C CG  . PRO   A 1 459 ? 158.903 122.243 111.856 1.00 66.84  ? 484 PRO   A CG  1 
ATOM   3716 C CD  . PRO   A 1 459 ? 159.471 123.330 112.719 1.00 67.47  ? 484 PRO   A CD  1 
ATOM   3717 N N   . ARG   A 1 460 ? 161.837 120.708 113.645 1.00 71.46  ? 485 ARG   A N   1 
ATOM   3718 C CA  . ARG   A 1 460 ? 162.994 119.884 113.318 1.00 67.38  ? 485 ARG   A CA  1 
ATOM   3719 C C   . ARG   A 1 460 ? 163.903 119.638 114.517 1.00 68.64  ? 485 ARG   A C   1 
ATOM   3720 O O   . ARG   A 1 460 ? 165.026 119.157 114.335 1.00 72.41  ? 485 ARG   A O   1 
ATOM   3721 C CB  . ARG   A 1 460 ? 163.801 120.542 112.198 1.00 66.41  ? 485 ARG   A CB  1 
ATOM   3722 C CG  . ARG   A 1 460 ? 163.015 120.832 110.929 1.00 68.60  ? 485 ARG   A CG  1 
ATOM   3723 C CD  . ARG   A 1 460 ? 163.818 121.685 109.962 1.00 73.40  ? 485 ARG   A CD  1 
ATOM   3724 N NE  . ARG   A 1 460 ? 164.051 123.028 110.482 1.00 77.14  ? 485 ARG   A NE  1 
ATOM   3725 C CZ  . ARG   A 1 460 ? 164.684 123.996 109.833 1.00 78.87  ? 485 ARG   A CZ  1 
ATOM   3726 N NH1 . ARG   A 1 460 ? 165.177 123.814 108.617 1.00 77.50  ? 485 ARG   A NH1 1 
ATOM   3727 N NH2 . ARG   A 1 460 ? 164.828 125.181 110.418 1.00 75.71  ? 485 ARG   A NH2 1 
ATOM   3728 N N   . VAL   A 1 461 ? 163.448 119.942 115.731 1.00 63.85  ? 486 VAL   A N   1 
ATOM   3729 C CA  . VAL   A 1 461 ? 164.277 119.913 116.929 1.00 62.96  ? 486 VAL   A CA  1 
ATOM   3730 C C   . VAL   A 1 461 ? 163.721 118.864 117.879 1.00 67.90  ? 486 VAL   A C   1 
ATOM   3731 O O   . VAL   A 1 461 ? 162.530 118.885 118.207 1.00 67.01  ? 486 VAL   A O   1 
ATOM   3732 C CB  . VAL   A 1 461 ? 164.329 121.291 117.614 1.00 66.65  ? 486 VAL   A CB  1 
ATOM   3733 C CG1 . VAL   A 1 461 ? 165.120 121.211 118.912 1.00 70.77  ? 486 VAL   A CG1 1 
ATOM   3734 C CG2 . VAL   A 1 461 ? 164.931 122.326 116.677 1.00 66.90  ? 486 VAL   A CG2 1 
ATOM   3735 N N   . ASP   A 1 462 ? 164.584 117.951 118.320 1.00 68.13  ? 487 ASP   A N   1 
ATOM   3736 C CA  . ASP   A 1 462 ? 164.212 116.963 119.327 1.00 63.69  ? 487 ASP   A CA  1 
ATOM   3737 C C   . ASP   A 1 462 ? 164.065 117.659 120.673 1.00 68.48  ? 487 ASP   A C   1 
ATOM   3738 O O   . ASP   A 1 462 ? 165.059 118.079 121.275 1.00 71.15  ? 487 ASP   A O   1 
ATOM   3739 C CB  . ASP   A 1 462 ? 165.263 115.861 119.392 1.00 65.64  ? 487 ASP   A CB  1 
ATOM   3740 C CG  . ASP   A 1 462 ? 164.875 114.739 120.331 1.00 73.16  ? 487 ASP   A CG  1 
ATOM   3741 O OD1 . ASP   A 1 462 ? 163.715 114.715 120.794 1.00 74.86  ? 487 ASP   A OD1 1 
ATOM   3742 O OD2 . ASP   A 1 462 ? 165.733 113.875 120.607 1.00 77.19  ? 487 ASP   A OD2 1 
ATOM   3743 N N   . ILE   A 1 463 ? 162.826 117.784 121.150 1.00 65.35  ? 488 ILE   A N   1 
ATOM   3744 C CA  . ILE   A 1 463 ? 162.583 118.496 122.397 1.00 59.84  ? 488 ILE   A CA  1 
ATOM   3745 C C   . ILE   A 1 463 ? 163.134 117.734 123.592 1.00 63.55  ? 488 ILE   A C   1 
ATOM   3746 O O   . ILE   A 1 463 ? 163.432 118.344 124.625 1.00 68.27  ? 488 ILE   A O   1 
ATOM   3747 C CB  . ILE   A 1 463 ? 161.077 118.774 122.579 1.00 60.07  ? 488 ILE   A CB  1 
ATOM   3748 C CG1 . ILE   A 1 463 ? 160.488 119.505 121.362 1.00 62.76  ? 488 ILE   A CG1 1 
ATOM   3749 C CG2 . ILE   A 1 463 ? 160.828 119.569 123.854 1.00 63.68  ? 488 ILE   A CG2 1 
ATOM   3750 C CD1 . ILE   A 1 463 ? 161.152 120.821 121.008 1.00 66.36  ? 488 ILE   A CD1 1 
ATOM   3751 N N   . VAL   A 1 464 ? 163.280 116.412 123.486 1.00 63.41  ? 489 VAL   A N   1 
ATOM   3752 C CA  . VAL   A 1 464 ? 163.792 115.634 124.610 1.00 61.76  ? 489 VAL   A CA  1 
ATOM   3753 C C   . VAL   A 1 464 ? 165.245 115.994 124.890 1.00 66.52  ? 489 VAL   A C   1 
ATOM   3754 O O   . VAL   A 1 464 ? 165.669 116.049 126.050 1.00 70.79  ? 489 VAL   A O   1 
ATOM   3755 C CB  . VAL   A 1 464 ? 163.626 114.128 124.340 1.00 62.33  ? 489 VAL   A CB  1 
ATOM   3756 C CG1 . VAL   A 1 464 ? 164.233 113.316 125.475 1.00 64.76  ? 489 VAL   A CG1 1 
ATOM   3757 C CG2 . VAL   A 1 464 ? 162.157 113.778 124.154 1.00 64.07  ? 489 VAL   A CG2 1 
ATOM   3758 N N   . GLN   A 1 465 ? 166.026 116.249 123.839 1.00 68.83  ? 490 GLN   A N   1 
ATOM   3759 C CA  . GLN   A 1 465 ? 167.432 116.617 123.956 1.00 66.97  ? 490 GLN   A CA  1 
ATOM   3760 C C   . GLN   A 1 465 ? 167.672 118.103 123.721 1.00 67.13  ? 490 GLN   A C   1 
ATOM   3761 O O   . GLN   A 1 465 ? 168.827 118.517 123.586 1.00 74.55  ? 490 GLN   A O   1 
ATOM   3762 C CB  . GLN   A 1 465 ? 168.275 115.798 122.976 1.00 69.05  ? 490 GLN   A CB  1 
ATOM   3763 C CG  . GLN   A 1 465 ? 168.159 114.289 123.142 1.00 74.39  ? 490 GLN   A CG  1 
ATOM   3764 C CD  . GLN   A 1 465 ? 168.692 113.803 124.471 1.00 80.72  ? 490 GLN   A CD  1 
ATOM   3765 O OE1 . GLN   A 1 465 ? 169.388 114.530 125.178 1.00 82.00  ? 490 GLN   A OE1 1 
ATOM   3766 N NE2 . GLN   A 1 465 ? 168.365 112.564 124.821 1.00 81.81  ? 490 GLN   A NE2 1 
ATOM   3767 N N   . ALA   A 1 466 ? 166.620 118.915 123.670 1.00 65.10  ? 491 ALA   A N   1 
ATOM   3768 C CA  . ALA   A 1 466 ? 166.794 120.343 123.463 1.00 64.94  ? 491 ALA   A CA  1 
ATOM   3769 C C   . ALA   A 1 466 ? 167.356 120.998 124.720 1.00 67.98  ? 491 ALA   A C   1 
ATOM   3770 O O   . ALA   A 1 466 ? 167.350 120.420 125.810 1.00 68.27  ? 491 ALA   A O   1 
ATOM   3771 C CB  . ALA   A 1 466 ? 165.466 120.995 123.079 1.00 68.42  ? 491 ALA   A CB  1 
ATOM   3772 N N   . ALA   A 1 467 ? 167.843 122.225 124.553 1.00 67.78  ? 492 ALA   A N   1 
ATOM   3773 C CA  . ALA   A 1 467 ? 168.484 122.977 125.624 1.00 67.74  ? 492 ALA   A CA  1 
ATOM   3774 C C   . ALA   A 1 467 ? 167.539 124.054 126.134 1.00 64.96  ? 492 ALA   A C   1 
ATOM   3775 O O   . ALA   A 1 467 ? 167.026 124.858 125.349 1.00 65.77  ? 492 ALA   A O   1 
ATOM   3776 C CB  . ALA   A 1 467 ? 169.785 123.614 125.135 1.00 67.91  ? 492 ALA   A CB  1 
ATOM   3777 N N   . TRP   A 1 468 ? 167.313 124.068 127.446 1.00 63.97  ? 493 TRP   A N   1 
ATOM   3778 C CA  . TRP   A 1 468 ? 166.450 125.063 128.067 1.00 62.01  ? 493 TRP   A CA  1 
ATOM   3779 C C   . TRP   A 1 468 ? 166.964 125.382 129.462 1.00 66.84  ? 493 TRP   A C   1 
ATOM   3780 O O   . TRP   A 1 468 ? 167.181 124.472 130.266 1.00 75.56  ? 493 TRP   A O   1 
ATOM   3781 C CB  . TRP   A 1 468 ? 165.004 124.571 128.144 1.00 57.77  ? 493 TRP   A CB  1 
ATOM   3782 C CG  . TRP   A 1 468 ? 164.103 125.503 128.881 1.00 57.98  ? 493 TRP   A CG  1 
ATOM   3783 C CD1 . TRP   A 1 468 ? 163.470 126.597 128.379 1.00 64.93  ? 493 TRP   A CD1 1 
ATOM   3784 C CD2 . TRP   A 1 468 ? 163.730 125.419 130.257 1.00 60.46  ? 493 TRP   A CD2 1 
ATOM   3785 N NE1 . TRP   A 1 468 ? 162.725 127.203 129.358 1.00 62.66  ? 493 TRP   A NE1 1 
ATOM   3786 C CE2 . TRP   A 1 468 ? 162.869 126.497 130.522 1.00 59.58  ? 493 TRP   A CE2 1 
ATOM   3787 C CE3 . TRP   A 1 468 ? 164.043 124.535 131.292 1.00 68.28  ? 493 TRP   A CE3 1 
ATOM   3788 C CZ2 . TRP   A 1 468 ? 162.319 126.719 131.778 1.00 65.58  ? 493 TRP   A CZ2 1 
ATOM   3789 C CZ3 . TRP   A 1 468 ? 163.495 124.755 132.538 1.00 70.20  ? 493 TRP   A CZ3 1 
ATOM   3790 C CH2 . TRP   A 1 468 ? 162.641 125.838 132.771 1.00 69.03  ? 493 TRP   A CH2 1 
ATOM   3791 N N   . SER   A 1 469 ? 167.162 126.672 129.734 1.00 67.05  ? 494 SER   A N   1 
ATOM   3792 C CA  . SER   A 1 469 ? 167.466 127.175 131.063 1.00 65.81  ? 494 SER   A CA  1 
ATOM   3793 C C   . SER   A 1 469 ? 166.578 128.379 131.348 1.00 68.02  ? 494 SER   A C   1 
ATOM   3794 O O   . SER   A 1 469 ? 166.197 129.088 130.410 1.00 72.33  ? 494 SER   A O   1 
ATOM   3795 C CB  . SER   A 1 469 ? 168.942 127.569 131.186 1.00 70.95  ? 494 SER   A CB  1 
ATOM   3796 O OG  . SER   A 1 469 ? 169.298 128.527 130.207 1.00 78.23  ? 494 SER   A OG  1 
ATOM   3797 N N   . PRO   A 1 470 ? 166.212 128.634 132.611 1.00 64.16  ? 495 PRO   A N   1 
ATOM   3798 C CA  . PRO   A 1 470 ? 165.247 129.716 132.873 1.00 63.32  ? 495 PRO   A CA  1 
ATOM   3799 C C   . PRO   A 1 470 ? 165.718 131.093 132.445 1.00 70.55  ? 495 PRO   A C   1 
ATOM   3800 O O   . PRO   A 1 470 ? 164.890 131.910 132.024 1.00 76.52  ? 495 PRO   A O   1 
ATOM   3801 C CB  . PRO   A 1 470 ? 165.047 129.652 134.393 1.00 66.92  ? 495 PRO   A CB  1 
ATOM   3802 C CG  . PRO   A 1 470 ? 165.522 128.323 134.801 1.00 69.26  ? 495 PRO   A CG  1 
ATOM   3803 C CD  . PRO   A 1 470 ? 166.616 127.968 133.863 1.00 69.97  ? 495 PRO   A CD  1 
ATOM   3804 N N   . PHE   A 1 471 ? 167.017 131.374 132.530 1.00 71.96  ? 496 PHE   A N   1 
ATOM   3805 C CA  . PHE   A 1 471 ? 167.545 132.723 132.369 1.00 70.40  ? 496 PHE   A CA  1 
ATOM   3806 C C   . PHE   A 1 471 ? 168.233 132.953 131.028 1.00 71.46  ? 496 PHE   A C   1 
ATOM   3807 O O   . PHE   A 1 471 ? 168.951 133.947 130.885 1.00 76.65  ? 496 PHE   A O   1 
ATOM   3808 C CB  . PHE   A 1 471 ? 168.513 133.031 133.509 1.00 69.64  ? 496 PHE   A CB  1 
ATOM   3809 C CG  . PHE   A 1 471 ? 167.929 132.806 134.870 1.00 72.92  ? 496 PHE   A CG  1 
ATOM   3810 C CD1 . PHE   A 1 471 ? 166.976 133.668 135.379 1.00 74.73  ? 496 PHE   A CD1 1 
ATOM   3811 C CD2 . PHE   A 1 471 ? 168.335 131.736 135.644 1.00 73.21  ? 496 PHE   A CD2 1 
ATOM   3812 C CE1 . PHE   A 1 471 ? 166.436 133.464 136.630 1.00 78.67  ? 496 PHE   A CE1 1 
ATOM   3813 C CE2 . PHE   A 1 471 ? 167.798 131.528 136.896 1.00 77.85  ? 496 PHE   A CE2 1 
ATOM   3814 C CZ  . PHE   A 1 471 ? 166.847 132.394 137.389 1.00 80.15  ? 496 PHE   A CZ  1 
ATOM   3815 N N   . GLN   A 1 472 ? 168.042 132.068 130.049 1.00 68.92  ? 497 GLN   A N   1 
ATOM   3816 C CA  . GLN   A 1 472 ? 168.567 132.254 128.703 1.00 69.00  ? 497 GLN   A CA  1 
ATOM   3817 C C   . GLN   A 1 472 ? 167.445 132.097 127.691 1.00 70.76  ? 497 GLN   A C   1 
ATOM   3818 O O   . GLN   A 1 472 ? 166.496 131.337 127.901 1.00 75.61  ? 497 GLN   A O   1 
ATOM   3819 C CB  . GLN   A 1 472 ? 169.689 131.260 128.385 1.00 74.19  ? 497 GLN   A CB  1 
ATOM   3820 C CG  . GLN   A 1 472 ? 170.925 131.430 129.244 1.00 83.27  ? 497 GLN   A CG  1 
ATOM   3821 C CD  . GLN   A 1 472 ? 172.073 130.555 128.787 1.00 92.79  ? 497 GLN   A CD  1 
ATOM   3822 O OE1 . GLN   A 1 472 ? 171.952 129.810 127.816 1.00 92.61  ? 497 GLN   A OE1 1 
ATOM   3823 N NE2 . GLN   A 1 472 ? 173.199 130.642 129.488 1.00 94.92  ? 497 GLN   A NE2 1 
ATOM   3824 N N   . ARG   A 1 473 ? 167.567 132.825 126.587 1.00 65.49  ? 498 ARG   A N   1 
ATOM   3825 C CA  . ARG   A 1 473 ? 166.546 132.800 125.552 1.00 67.96  ? 498 ARG   A CA  1 
ATOM   3826 C C   . ARG   A 1 473 ? 166.496 131.433 124.884 1.00 72.01  ? 498 ARG   A C   1 
ATOM   3827 O O   . ARG   A 1 473 ? 167.531 130.819 124.609 1.00 76.30  ? 498 ARG   A O   1 
ATOM   3828 C CB  . ARG   A 1 473 ? 166.831 133.883 124.513 1.00 74.13  ? 498 ARG   A CB  1 
ATOM   3829 C CG  . ARG   A 1 473 ? 165.712 134.102 123.511 1.00 81.50  ? 498 ARG   A CG  1 
ATOM   3830 C CD  . ARG   A 1 473 ? 166.050 135.212 122.525 1.00 89.81  ? 498 ARG   A CD  1 
ATOM   3831 N NE  . ARG   A 1 473 ? 166.199 136.508 123.178 1.00 97.82  ? 498 ARG   A NE  1 
ATOM   3832 C CZ  . ARG   A 1 473 ? 166.538 137.634 122.562 1.00 103.25 ? 498 ARG   A CZ  1 
ATOM   3833 N NH1 . ARG   A 1 473 ? 166.778 137.673 121.260 1.00 104.27 ? 498 ARG   A NH1 1 
ATOM   3834 N NH2 . ARG   A 1 473 ? 166.638 138.754 123.272 1.00 96.84  ? 498 ARG   A NH2 1 
ATOM   3835 N N   . THR   A 1 474 ? 165.282 130.957 124.622 1.00 67.83  ? 499 THR   A N   1 
ATOM   3836 C CA  . THR   A 1 474 ? 165.107 129.688 123.932 1.00 61.54  ? 499 THR   A CA  1 
ATOM   3837 C C   . THR   A 1 474 ? 165.416 129.854 122.451 1.00 62.53  ? 499 THR   A C   1 
ATOM   3838 O O   . THR   A 1 474 ? 164.942 130.797 121.811 1.00 65.66  ? 499 THR   A O   1 
ATOM   3839 C CB  . THR   A 1 474 ? 163.683 129.175 124.122 1.00 63.86  ? 499 THR   A CB  1 
ATOM   3840 O OG1 . THR   A 1 474 ? 162.752 130.173 123.689 1.00 70.52  ? 499 THR   A OG1 1 
ATOM   3841 C CG2 . THR   A 1 474 ? 163.426 128.847 125.577 1.00 65.00  ? 499 THR   A CG2 1 
ATOM   3842 N N   . SER   A 1 475 ? 166.205 128.934 121.905 1.00 61.69  ? 500 SER   A N   1 
ATOM   3843 C CA  . SER   A 1 475 ? 166.654 129.008 120.521 1.00 59.34  ? 500 SER   A CA  1 
ATOM   3844 C C   . SER   A 1 475 ? 165.732 128.297 119.537 1.00 66.15  ? 500 SER   A C   1 
ATOM   3845 O O   . SER   A 1 475 ? 165.996 128.348 118.332 1.00 68.33  ? 500 SER   A O   1 
ATOM   3846 C CB  . SER   A 1 475 ? 168.062 128.422 120.401 1.00 59.96  ? 500 SER   A CB  1 
ATOM   3847 O OG  . SER   A 1 475 ? 168.076 127.051 120.755 1.00 63.07  ? 500 SER   A OG  1 
ATOM   3848 N N   . TRP   A 1 476 ? 164.667 127.644 120.008 1.00 65.19  ? 501 TRP   A N   1 
ATOM   3849 C CA  . TRP   A 1 476 ? 163.733 126.907 119.162 1.00 58.22  ? 501 TRP   A CA  1 
ATOM   3850 C C   . TRP   A 1 476 ? 162.309 127.423 119.344 1.00 61.61  ? 501 TRP   A C   1 
ATOM   3851 O O   . TRP   A 1 476 ? 161.352 126.653 119.436 1.00 67.54  ? 501 TRP   A O   1 
ATOM   3852 C CB  . TRP   A 1 476 ? 163.821 125.403 119.432 1.00 56.76  ? 501 TRP   A CB  1 
ATOM   3853 C CG  . TRP   A 1 476 ? 163.925 125.014 120.875 1.00 58.08  ? 501 TRP   A CG  1 
ATOM   3854 C CD1 . TRP   A 1 476 ? 165.067 124.912 121.608 1.00 64.70  ? 501 TRP   A CD1 1 
ATOM   3855 C CD2 . TRP   A 1 476 ? 162.853 124.660 121.755 1.00 59.55  ? 501 TRP   A CD2 1 
ATOM   3856 N NE1 . TRP   A 1 476 ? 164.776 124.525 122.890 1.00 67.20  ? 501 TRP   A NE1 1 
ATOM   3857 C CE2 . TRP   A 1 476 ? 163.423 124.363 123.006 1.00 58.41  ? 501 TRP   A CE2 1 
ATOM   3858 C CE3 . TRP   A 1 476 ? 161.467 124.568 121.610 1.00 66.54  ? 501 TRP   A CE3 1 
ATOM   3859 C CZ2 . TRP   A 1 476 ? 162.659 123.983 124.101 1.00 59.17  ? 501 TRP   A CZ2 1 
ATOM   3860 C CZ3 . TRP   A 1 476 ? 160.712 124.191 122.701 1.00 65.70  ? 501 TRP   A CZ3 1 
ATOM   3861 C CH2 . TRP   A 1 476 ? 161.309 123.905 123.929 1.00 61.72  ? 501 TRP   A CH2 1 
ATOM   3862 N N   . VAL   A 1 477 ? 162.157 128.745 119.396 1.00 59.25  ? 502 VAL   A N   1 
ATOM   3863 C CA  . VAL   A 1 477 ? 160.857 129.408 119.381 1.00 58.38  ? 502 VAL   A CA  1 
ATOM   3864 C C   . VAL   A 1 477 ? 160.855 130.373 118.204 1.00 64.64  ? 502 VAL   A C   1 
ATOM   3865 O O   . VAL   A 1 477 ? 161.641 131.327 118.176 1.00 71.47  ? 502 VAL   A O   1 
ATOM   3866 C CB  . VAL   A 1 477 ? 160.567 130.142 120.699 1.00 59.21  ? 502 VAL   A CB  1 
ATOM   3867 C CG1 . VAL   A 1 477 ? 159.253 130.896 120.608 1.00 63.04  ? 502 VAL   A CG1 1 
ATOM   3868 C CG2 . VAL   A 1 477 ? 160.542 129.158 121.861 1.00 63.88  ? 502 VAL   A CG2 1 
ATOM   3869 N N   . GLN   A 1 478 ? 159.977 130.124 117.238 1.00 67.01  ? 503 GLN   A N   1 
ATOM   3870 C CA  . GLN   A 1 478 ? 159.946 130.945 116.038 1.00 64.13  ? 503 GLN   A CA  1 
ATOM   3871 C C   . GLN   A 1 478 ? 159.472 132.357 116.382 1.00 58.85  ? 503 GLN   A C   1 
ATOM   3872 O O   . GLN   A 1 478 ? 158.599 132.523 117.239 1.00 66.22  ? 503 GLN   A O   1 
ATOM   3873 C CB  . GLN   A 1 478 ? 159.016 130.332 114.992 1.00 66.54  ? 503 GLN   A CB  1 
ATOM   3874 C CG  . GLN   A 1 478 ? 159.436 128.965 114.480 1.00 68.23  ? 503 GLN   A CG  1 
ATOM   3875 C CD  . GLN   A 1 478 ? 160.597 129.031 113.511 1.00 74.19  ? 503 GLN   A CD  1 
ATOM   3876 O OE1 . GLN   A 1 478 ? 161.227 130.074 113.346 1.00 74.12  ? 503 GLN   A OE1 1 
ATOM   3877 N NE2 . GLN   A 1 478 ? 160.886 127.913 112.861 1.00 74.84  ? 503 GLN   A NE2 1 
ATOM   3878 N N   . PRO   A 1 479 ? 160.016 133.395 115.743 1.00 56.90  ? 504 PRO   A N   1 
ATOM   3879 C CA  . PRO   A 1 479 ? 159.543 134.750 116.039 1.00 62.42  ? 504 PRO   A CA  1 
ATOM   3880 C C   . PRO   A 1 479 ? 158.133 134.985 115.527 1.00 64.70  ? 504 PRO   A C   1 
ATOM   3881 O O   . PRO   A 1 479 ? 157.687 134.371 114.555 1.00 67.62  ? 504 PRO   A O   1 
ATOM   3882 C CB  . PRO   A 1 479 ? 160.552 135.644 115.312 1.00 65.39  ? 504 PRO   A CB  1 
ATOM   3883 C CG  . PRO   A 1 479 ? 161.032 134.818 114.197 1.00 65.53  ? 504 PRO   A CG  1 
ATOM   3884 C CD  . PRO   A 1 479 ? 161.073 133.416 114.715 1.00 65.87  ? 504 PRO   A CD  1 
ATOM   3885 N N   . LEU   A 1 480 ? 157.428 135.892 116.197 1.00 61.63  ? 505 LEU   A N   1 
ATOM   3886 C CA  . LEU   A 1 480 ? 156.120 136.333 115.735 1.00 60.52  ? 505 LEU   A CA  1 
ATOM   3887 C C   . LEU   A 1 480 ? 156.318 137.276 114.557 1.00 67.06  ? 505 LEU   A C   1 
ATOM   3888 O O   . LEU   A 1 480 ? 156.914 138.348 114.708 1.00 73.23  ? 505 LEU   A O   1 
ATOM   3889 C CB  . LEU   A 1 480 ? 155.356 137.027 116.861 1.00 64.78  ? 505 LEU   A CB  1 
ATOM   3890 C CG  . LEU   A 1 480 ? 153.824 136.958 116.843 1.00 66.45  ? 505 LEU   A CG  1 
ATOM   3891 C CD1 . LEU   A 1 480 ? 153.248 137.773 117.985 1.00 67.22  ? 505 LEU   A CD1 1 
ATOM   3892 C CD2 . LEU   A 1 480 ? 153.241 137.424 115.523 1.00 67.28  ? 505 LEU   A CD2 1 
ATOM   3893 N N   . LEU   A 1 481 ? 155.825 136.882 113.388 1.00 67.53  ? 506 LEU   A N   1 
ATOM   3894 C CA  . LEU   A 1 481 ? 155.943 137.708 112.191 1.00 67.74  ? 506 LEU   A CA  1 
ATOM   3895 C C   . LEU   A 1 481 ? 154.909 138.820 112.288 1.00 71.00  ? 506 LEU   A C   1 
ATOM   3896 O O   . LEU   A 1 481 ? 153.759 138.669 111.877 1.00 71.40  ? 506 LEU   A O   1 
ATOM   3897 C CB  . LEU   A 1 481 ? 155.750 136.871 110.934 1.00 64.19  ? 506 LEU   A CB  1 
ATOM   3898 C CG  . LEU   A 1 481 ? 156.792 135.787 110.660 1.00 68.59  ? 506 LEU   A CG  1 
ATOM   3899 C CD1 . LEU   A 1 481 ? 156.321 134.884 109.539 1.00 68.36  ? 506 LEU   A CD1 1 
ATOM   3900 C CD2 . LEU   A 1 481 ? 158.142 136.396 110.317 1.00 72.44  ? 506 LEU   A CD2 1 
ATOM   3901 N N   . MET   A 1 482 ? 155.329 139.956 112.839 1.00 74.57  ? 507 MET   A N   1 
ATOM   3902 C CA  . MET   A 1 482 ? 154.450 141.104 113.006 1.00 77.71  ? 507 MET   A CA  1 
ATOM   3903 C C   . MET   A 1 482 ? 154.372 141.981 111.764 1.00 76.21  ? 507 MET   A C   1 
ATOM   3904 O O   . MET   A 1 482 ? 153.542 142.895 111.726 1.00 80.86  ? 507 MET   A O   1 
ATOM   3905 C CB  . MET   A 1 482 ? 154.913 141.953 114.193 1.00 79.71  ? 507 MET   A CB  1 
ATOM   3906 C CG  . MET   A 1 482 ? 154.978 141.189 115.504 1.00 77.70  ? 507 MET   A CG  1 
ATOM   3907 S SD  . MET   A 1 482 ? 154.898 142.258 116.950 1.00 107.44 ? 507 MET   A SD  1 
ATOM   3908 C CE  . MET   A 1 482 ? 153.167 142.715 116.933 1.00 90.00  ? 507 MET   A CE  1 
ATOM   3909 N N   . ASP   A 1 483 ? 155.207 141.732 110.754 1.00 73.11  ? 508 ASP   A N   1 
ATOM   3910 C CA  . ASP   A 1 483 ? 155.146 142.522 109.532 1.00 75.10  ? 508 ASP   A CA  1 
ATOM   3911 C C   . ASP   A 1 483 ? 153.872 142.264 108.739 1.00 76.87  ? 508 ASP   A C   1 
ATOM   3912 O O   . ASP   A 1 483 ? 153.469 143.124 107.949 1.00 80.92  ? 508 ASP   A O   1 
ATOM   3913 C CB  . ASP   A 1 483 ? 156.366 142.229 108.661 1.00 78.78  ? 508 ASP   A CB  1 
ATOM   3914 C CG  . ASP   A 1 483 ? 157.667 142.517 109.373 1.00 84.72  ? 508 ASP   A CG  1 
ATOM   3915 O OD1 . ASP   A 1 483 ? 157.620 142.908 110.557 1.00 90.48  ? 508 ASP   A OD1 1 
ATOM   3916 O OD2 . ASP   A 1 483 ? 158.737 142.353 108.752 1.00 90.20  ? 508 ASP   A OD2 1 
ATOM   3917 N N   . LEU   A 1 484 ? 153.232 141.109 108.929 1.00 72.28  ? 509 LEU   A N   1 
ATOM   3918 C CA  . LEU   A 1 484 ? 151.982 140.780 108.260 1.00 70.80  ? 509 LEU   A CA  1 
ATOM   3919 C C   . LEU   A 1 484 ? 150.757 141.218 109.062 1.00 71.85  ? 509 LEU   A C   1 
ATOM   3920 O O   . LEU   A 1 484 ? 149.651 140.733 108.803 1.00 73.80  ? 509 LEU   A O   1 
ATOM   3921 C CB  . LEU   A 1 484 ? 151.910 139.275 107.980 1.00 69.05  ? 509 LEU   A CB  1 
ATOM   3922 C CG  . LEU   A 1 484 ? 152.990 138.591 107.124 1.00 69.36  ? 509 LEU   A CG  1 
ATOM   3923 C CD1 . LEU   A 1 484 ? 153.361 139.421 105.899 1.00 72.99  ? 509 LEU   A CD1 1 
ATOM   3924 C CD2 . LEU   A 1 484 ? 154.230 138.244 107.929 1.00 69.85  ? 509 LEU   A CD2 1 
ATOM   3925 N N   . SER   A 1 485 ? 150.933 142.113 110.032 1.00 69.64  ? 510 SER   A N   1 
ATOM   3926 C CA  . SER   A 1 485 ? 149.800 142.622 110.804 1.00 69.04  ? 510 SER   A CA  1 
ATOM   3927 C C   . SER   A 1 485 ? 148.759 143.356 109.964 1.00 71.16  ? 510 SER   A C   1 
ATOM   3928 O O   . SER   A 1 485 ? 147.560 143.087 110.150 1.00 74.17  ? 510 SER   A O   1 
ATOM   3929 C CB  . SER   A 1 485 ? 150.323 143.517 111.930 1.00 75.88  ? 510 SER   A CB  1 
ATOM   3930 O OG  . SER   A 1 485 ? 151.103 142.770 112.847 1.00 82.56  ? 510 SER   A OG  1 
ATOM   3931 N N   . PRO   A 1 486 ? 149.109 144.289 109.067 1.00 69.78  ? 511 PRO   A N   1 
ATOM   3932 C CA  . PRO   A 1 486 ? 148.052 145.002 108.322 1.00 67.44  ? 511 PRO   A CA  1 
ATOM   3933 C C   . PRO   A 1 486 ? 147.180 144.107 107.458 1.00 69.73  ? 511 PRO   A C   1 
ATOM   3934 O O   . PRO   A 1 486 ? 146.026 144.475 107.183 1.00 77.26  ? 511 PRO   A O   1 
ATOM   3935 C CB  . PRO   A 1 486 ? 148.831 146.014 107.471 1.00 71.02  ? 511 PRO   A CB  1 
ATOM   3936 C CG  . PRO   A 1 486 ? 150.236 145.592 107.525 1.00 73.46  ? 511 PRO   A CG  1 
ATOM   3937 C CD  . PRO   A 1 486 ? 150.423 144.911 108.829 1.00 72.93  ? 511 PRO   A CD  1 
ATOM   3938 N N   . TRP   A 1 487 ? 147.664 142.924 107.068 1.00 65.60  ? 512 TRP   A N   1 
ATOM   3939 C CA  . TRP   A 1 487 ? 146.880 142.033 106.220 1.00 69.03  ? 512 TRP   A CA  1 
ATOM   3940 C C   . TRP   A 1 487 ? 145.547 141.653 106.850 1.00 71.37  ? 512 TRP   A C   1 
ATOM   3941 O O   . TRP   A 1 487 ? 144.611 141.308 106.120 1.00 79.14  ? 512 TRP   A O   1 
ATOM   3942 C CB  . TRP   A 1 487 ? 147.668 140.760 105.915 1.00 68.30  ? 512 TRP   A CB  1 
ATOM   3943 C CG  . TRP   A 1 487 ? 148.616 140.880 104.771 1.00 64.71  ? 512 TRP   A CG  1 
ATOM   3944 C CD1 . TRP   A 1 487 ? 149.895 141.339 104.814 1.00 66.31  ? 512 TRP   A CD1 1 
ATOM   3945 C CD2 . TRP   A 1 487 ? 148.364 140.520 103.411 1.00 66.68  ? 512 TRP   A CD2 1 
ATOM   3946 N NE1 . TRP   A 1 487 ? 150.457 141.292 103.564 1.00 68.86  ? 512 TRP   A NE1 1 
ATOM   3947 C CE2 . TRP   A 1 487 ? 149.536 140.791 102.684 1.00 65.11  ? 512 TRP   A CE2 1 
ATOM   3948 C CE3 . TRP   A 1 487 ? 147.260 139.994 102.737 1.00 71.41  ? 512 TRP   A CE3 1 
ATOM   3949 C CZ2 . TRP   A 1 487 ? 149.635 140.560 101.318 1.00 69.53  ? 512 TRP   A CZ2 1 
ATOM   3950 C CZ3 . TRP   A 1 487 ? 147.360 139.765 101.382 1.00 72.93  ? 512 TRP   A CZ3 1 
ATOM   3951 C CH2 . TRP   A 1 487 ? 148.539 140.047 100.686 1.00 72.12  ? 512 TRP   A CH2 1 
ATOM   3952 N N   . ARG   A 1 488 ? 145.423 141.765 108.177 1.00 66.55  ? 513 ARG   A N   1 
ATOM   3953 C CA  . ARG   A 1 488 ? 144.171 141.465 108.858 1.00 65.34  ? 513 ARG   A CA  1 
ATOM   3954 C C   . ARG   A 1 488 ? 143.009 142.288 108.326 1.00 71.74  ? 513 ARG   A C   1 
ATOM   3955 O O   . ARG   A 1 488 ? 141.857 141.864 108.461 1.00 77.30  ? 513 ARG   A O   1 
ATOM   3956 C CB  . ARG   A 1 488 ? 144.314 141.707 110.357 1.00 64.74  ? 513 ARG   A CB  1 
ATOM   3957 C CG  . ARG   A 1 488 ? 145.348 140.831 111.021 1.00 67.65  ? 513 ARG   A CG  1 
ATOM   3958 C CD  . ARG   A 1 488 ? 145.371 141.044 112.522 1.00 67.42  ? 513 ARG   A CD  1 
ATOM   3959 N NE  . ARG   A 1 488 ? 146.055 142.279 112.886 1.00 66.83  ? 513 ARG   A NE  1 
ATOM   3960 C CZ  . ARG   A 1 488 ? 146.321 142.661 114.128 1.00 70.58  ? 513 ARG   A CZ  1 
ATOM   3961 N NH1 . ARG   A 1 488 ? 145.968 141.929 115.173 1.00 69.04  ? 513 ARG   A NH1 1 
ATOM   3962 N NH2 . ARG   A 1 488 ? 146.963 143.808 114.329 1.00 73.76  ? 513 ARG   A NH2 1 
ATOM   3963 N N   . ALA   A 1 489 ? 143.270 143.454 107.734 1.00 76.07  ? 514 ALA   A N   1 
ATOM   3964 C CA  . ALA   A 1 489 ? 142.195 144.152 107.040 1.00 80.82  ? 514 ALA   A CA  1 
ATOM   3965 C C   . ALA   A 1 489 ? 141.711 143.333 105.849 1.00 82.67  ? 514 ALA   A C   1 
ATOM   3966 O O   . ALA   A 1 489 ? 140.560 142.877 105.817 1.00 83.93  ? 514 ALA   A O   1 
ATOM   3967 C CB  . ALA   A 1 489 ? 142.670 145.535 106.593 1.00 78.58  ? 514 ALA   A CB  1 
ATOM   3968 N N   . LYS   A 1 490 ? 142.612 143.070 104.895 1.00 85.17  ? 515 LYS   A N   1 
ATOM   3969 C CA  . LYS   A 1 490 ? 142.219 142.437 103.639 1.00 83.19  ? 515 LYS   A CA  1 
ATOM   3970 C C   . LYS   A 1 490 ? 141.627 141.056 103.875 1.00 78.82  ? 515 LYS   A C   1 
ATOM   3971 O O   . LYS   A 1 490 ? 140.611 140.700 103.264 1.00 81.68  ? 515 LYS   A O   1 
ATOM   3972 C CB  . LYS   A 1 490 ? 143.420 142.343 102.698 1.00 84.01  ? 515 LYS   A CB  1 
ATOM   3973 C CG  . LYS   A 1 490 ? 144.005 143.694 102.302 1.00 92.50  ? 515 LYS   A CG  1 
ATOM   3974 C CD  . LYS   A 1 490 ? 145.251 143.558 101.424 1.00 96.96  ? 515 LYS   A CD  1 
ATOM   3975 C CE  . LYS   A 1 490 ? 144.949 142.983 100.041 1.00 99.02  ? 515 LYS   A CE  1 
ATOM   3976 N NZ  . LYS   A 1 490 ? 143.943 143.781 99.284  1.00 102.10 ? 515 LYS   A NZ  1 
ATOM   3977 N N   . LEU   A 1 491 ? 142.243 140.273 104.769 1.00 78.29  ? 516 LEU   A N   1 
ATOM   3978 C CA  . LEU   A 1 491 ? 141.735 138.943 105.085 1.00 78.34  ? 516 LEU   A CA  1 
ATOM   3979 C C   . LEU   A 1 491 ? 140.270 138.993 105.487 1.00 79.56  ? 516 LEU   A C   1 
ATOM   3980 O O   . LEU   A 1 491 ? 139.473 138.153 105.050 1.00 87.46  ? 516 LEU   A O   1 
ATOM   3981 C CB  . LEU   A 1 491 ? 142.558 138.309 106.209 1.00 77.30  ? 516 LEU   A CB  1 
ATOM   3982 C CG  . LEU   A 1 491 ? 144.048 138.038 105.991 1.00 77.66  ? 516 LEU   A CG  1 
ATOM   3983 C CD1 . LEU   A 1 491 ? 144.613 137.297 107.189 1.00 73.05  ? 516 LEU   A CD1 1 
ATOM   3984 C CD2 . LEU   A 1 491 ? 144.305 137.264 104.710 1.00 81.17  ? 516 LEU   A CD2 1 
ATOM   3985 N N   . GLN   A 1 492 ? 139.888 139.999 106.280 1.00 78.45  ? 517 GLN   A N   1 
ATOM   3986 C CA  . GLN   A 1 492 ? 138.502 140.084 106.723 1.00 82.97  ? 517 GLN   A CA  1 
ATOM   3987 C C   . GLN   A 1 492 ? 137.569 140.235 105.532 1.00 88.95  ? 517 GLN   A C   1 
ATOM   3988 O O   . GLN   A 1 492 ? 136.511 139.595 105.479 1.00 91.76  ? 517 GLN   A O   1 
ATOM   3989 C CB  . GLN   A 1 492 ? 138.327 141.247 107.700 1.00 84.53  ? 517 GLN   A CB  1 
ATOM   3990 C CG  . GLN   A 1 492 ? 137.247 141.023 108.751 1.00 89.25  ? 517 GLN   A CG  1 
ATOM   3991 C CD  . GLN   A 1 492 ? 135.846 141.024 108.175 1.00 98.33  ? 517 GLN   A CD  1 
ATOM   3992 O OE1 . GLN   A 1 492 ? 135.566 141.707 107.190 1.00 98.11  ? 517 GLN   A OE1 1 
ATOM   3993 N NE2 . GLN   A 1 492 ? 134.953 140.257 108.791 1.00 100.39 ? 517 GLN   A NE2 1 
ATOM   3994 N N   . GLU   A 1 493 ? 137.966 141.048 104.548 1.00 87.78  ? 518 GLU   A N   1 
ATOM   3995 C CA  . GLU   A 1 493 ? 137.176 141.169 103.329 1.00 85.07  ? 518 GLU   A CA  1 
ATOM   3996 C C   . GLU   A 1 493 ? 137.006 139.811 102.666 1.00 86.42  ? 518 GLU   A C   1 
ATOM   3997 O O   . GLU   A 1 493 ? 135.895 139.438 102.269 1.00 90.59  ? 518 GLU   A O   1 
ATOM   3998 C CB  . GLU   A 1 493 ? 137.839 142.158 102.373 1.00 86.94  ? 518 GLU   A CB  1 
ATOM   3999 C CG  . GLU   A 1 493 ? 137.000 142.517 101.159 1.00 93.46  ? 518 GLU   A CG  1 
ATOM   4000 C CD  . GLU   A 1 493 ? 137.676 143.540 100.269 1.00 101.40 ? 518 GLU   A CD  1 
ATOM   4001 O OE1 . GLU   A 1 493 ? 138.804 143.963 100.599 1.00 101.01 ? 518 GLU   A OE1 1 
ATOM   4002 O OE2 . GLU   A 1 493 ? 137.081 143.921 99.239  1.00 98.94  ? 518 GLU   A OE2 1 
ATOM   4003 N N   . ILE   A 1 494 ? 138.089 139.035 102.585 1.00 83.07  ? 519 ILE   A N   1 
ATOM   4004 C CA  . ILE   A 1 494 ? 138.006 137.712 101.979 1.00 77.56  ? 519 ILE   A CA  1 
ATOM   4005 C C   . ILE   A 1 494 ? 137.100 136.814 102.808 1.00 77.54  ? 519 ILE   A C   1 
ATOM   4006 O O   . ILE   A 1 494 ? 136.420 135.931 102.274 1.00 84.98  ? 519 ILE   A O   1 
ATOM   4007 C CB  . ILE   A 1 494 ? 139.411 137.105 101.809 1.00 79.77  ? 519 ILE   A CB  1 
ATOM   4008 C CG1 . ILE   A 1 494 ? 140.248 137.945 100.833 1.00 83.83  ? 519 ILE   A CG1 1 
ATOM   4009 C CG2 . ILE   A 1 494 ? 139.297 135.668 101.316 1.00 78.39  ? 519 ILE   A CG2 1 
ATOM   4010 C CD1 . ILE   A 1 494 ? 141.734 137.640 100.859 1.00 82.21  ? 519 ILE   A CD1 1 
ATOM   4011 N N   . LYS   A 1 495 ? 137.076 137.021 104.126 1.00 79.67  ? 520 LYS   A N   1 
ATOM   4012 C CA  . LYS   A 1 495 ? 136.178 136.241 104.966 1.00 82.12  ? 520 LYS   A CA  1 
ATOM   4013 C C   . LYS   A 1 495 ? 134.715 136.543 104.673 1.00 85.70  ? 520 LYS   A C   1 
ATOM   4014 O O   . LYS   A 1 495 ? 133.860 135.686 104.919 1.00 86.41  ? 520 LYS   A O   1 
ATOM   4015 C CB  . LYS   A 1 495 ? 136.485 136.499 106.445 1.00 86.28  ? 520 LYS   A CB  1 
ATOM   4016 C CG  . LYS   A 1 495 ? 135.734 135.608 107.444 1.00 89.55  ? 520 LYS   A CG  1 
ATOM   4017 C CD  . LYS   A 1 495 ? 136.087 134.123 107.342 1.00 91.26  ? 520 LYS   A CD  1 
ATOM   4018 C CE  . LYS   A 1 495 ? 137.549 133.830 107.669 1.00 91.81  ? 520 LYS   A CE  1 
ATOM   4019 N NZ  . LYS   A 1 495 ? 137.968 134.347 109.001 1.00 95.65  ? 520 LYS   A NZ  1 
ATOM   4020 N N   . SER   A 1 496 ? 134.405 137.732 104.152 1.00 86.62  ? 521 SER   A N   1 
ATOM   4021 C CA  . SER   A 1 496 ? 133.028 138.143 103.910 1.00 84.88  ? 521 SER   A CA  1 
ATOM   4022 C C   . SER   A 1 496 ? 132.570 137.914 102.475 1.00 86.17  ? 521 SER   A C   1 
ATOM   4023 O O   . SER   A 1 496 ? 131.433 138.264 102.146 1.00 92.15  ? 521 SER   A O   1 
ATOM   4024 C CB  . SER   A 1 496 ? 132.855 139.622 104.266 1.00 88.82  ? 521 SER   A CB  1 
ATOM   4025 O OG  . SER   A 1 496 ? 133.670 140.443 103.449 1.00 92.35  ? 521 SER   A OG  1 
ATOM   4026 N N   . SER   A 1 497 ? 133.412 137.333 101.621 1.00 83.51  ? 522 SER   A N   1 
ATOM   4027 C CA  . SER   A 1 497 ? 133.085 137.094 100.221 1.00 86.02  ? 522 SER   A CA  1 
ATOM   4028 C C   . SER   A 1 497 ? 132.716 135.643 99.938  1.00 87.80  ? 522 SER   A C   1 
ATOM   4029 O O   . SER   A 1 497 ? 132.594 135.268 98.769  1.00 95.76  ? 522 SER   A O   1 
ATOM   4030 C CB  . SER   A 1 497 ? 134.260 137.511 99.335  1.00 91.09  ? 522 SER   A CB  1 
ATOM   4031 O OG  . SER   A 1 497 ? 133.956 137.335 97.962  1.00 101.44 ? 522 SER   A OG  1 
ATOM   4032 N N   . LEU   A 1 498 ? 132.532 134.826 100.971 1.00 83.60  ? 523 LEU   A N   1 
ATOM   4033 C CA  . LEU   A 1 498 ? 132.258 133.406 100.816 1.00 86.56  ? 523 LEU   A CA  1 
ATOM   4034 C C   . LEU   A 1 498 ? 130.763 133.135 100.931 1.00 86.61  ? 523 LEU   A C   1 
ATOM   4035 O O   . LEU   A 1 498 ? 129.977 133.981 101.361 1.00 89.17  ? 523 LEU   A O   1 
ATOM   4036 C CB  . LEU   A 1 498 ? 133.020 132.594 101.868 1.00 85.19  ? 523 LEU   A CB  1 
ATOM   4037 C CG  . LEU   A 1 498 ? 134.544 132.728 101.896 1.00 86.72  ? 523 LEU   A CG  1 
ATOM   4038 C CD1 . LEU   A 1 498 ? 135.105 131.941 103.064 1.00 86.78  ? 523 LEU   A CD1 1 
ATOM   4039 C CD2 . LEU   A 1 498 ? 135.165 132.260 100.595 1.00 87.43  ? 523 LEU   A CD2 1 
ATOM   4040 N N   . ASP   A 1 499 ? 130.378 131.924 100.540 1.00 87.63  ? 524 ASP   A N   1 
ATOM   4041 C CA  . ASP   A 1 499 ? 128.999 131.474 100.662 1.00 86.49  ? 524 ASP   A CA  1 
ATOM   4042 C C   . ASP   A 1 499 ? 128.754 131.029 102.100 1.00 89.48  ? 524 ASP   A C   1 
ATOM   4043 O O   . ASP   A 1 499 ? 129.584 131.233 102.990 1.00 93.66  ? 524 ASP   A O   1 
ATOM   4044 C CB  . ASP   A 1 499 ? 128.719 130.353 99.667  1.00 87.02  ? 524 ASP   A CB  1 
ATOM   4045 C CG  . ASP   A 1 499 ? 129.154 130.699 98.260  1.00 100.26 ? 524 ASP   A CG  1 
ATOM   4046 O OD1 . ASP   A 1 499 ? 129.635 131.832 98.048  1.00 103.97 ? 524 ASP   A OD1 1 
ATOM   4047 O OD2 . ASP   A 1 499 ? 129.017 129.839 97.365  1.00 103.91 ? 524 ASP   A OD2 1 
ATOM   4048 N N   . ASN   A 1 500 ? 127.603 130.409 102.346 1.00 88.43  ? 525 ASN   A N   1 
ATOM   4049 C CA  . ASN   A 1 500 ? 127.295 129.860 103.659 1.00 87.27  ? 525 ASN   A CA  1 
ATOM   4050 C C   . ASN   A 1 500 ? 127.898 128.478 103.883 1.00 86.25  ? 525 ASN   A C   1 
ATOM   4051 O O   . ASN   A 1 500 ? 127.759 127.939 104.985 1.00 87.10  ? 525 ASN   A O   1 
ATOM   4052 C CB  . ASN   A 1 500 ? 125.779 129.793 103.854 1.00 93.22  ? 525 ASN   A CB  1 
ATOM   4053 C CG  . ASN   A 1 500 ? 125.126 131.162 103.816 1.00 97.08  ? 525 ASN   A CG  1 
ATOM   4054 O OD1 . ASN   A 1 500 ? 125.725 132.134 103.359 1.00 95.39  ? 525 ASN   A OD1 1 
ATOM   4055 N ND2 . ASN   A 1 500 ? 123.890 131.244 104.296 1.00 93.70  ? 525 ASN   A ND2 1 
ATOM   4056 N N   . HIS   A 1 501 ? 128.564 127.902 102.880 1.00 88.90  ? 526 HIS   A N   1 
ATOM   4057 C CA  . HIS   A 1 501 ? 129.183 126.583 102.969 1.00 87.88  ? 526 HIS   A CA  1 
ATOM   4058 C C   . HIS   A 1 501 ? 130.700 126.624 102.919 1.00 84.81  ? 526 HIS   A C   1 
ATOM   4059 O O   . HIS   A 1 501 ? 131.356 125.867 103.637 1.00 83.01  ? 526 HIS   A O   1 
ATOM   4060 C CB  . HIS   A 1 501 ? 128.676 125.691 101.832 1.00 88.32  ? 526 HIS   A CB  1 
ATOM   4061 C CG  . HIS   A 1 501 ? 127.186 125.570 101.777 1.00 97.00  ? 526 HIS   A CG  1 
ATOM   4062 N ND1 . HIS   A 1 501 ? 126.475 124.741 102.616 1.00 104.24 ? 526 HIS   A ND1 1 
ATOM   4063 C CD2 . HIS   A 1 501 ? 126.273 126.169 100.977 1.00 100.48 ? 526 HIS   A CD2 1 
ATOM   4064 C CE1 . HIS   A 1 501 ? 125.187 124.837 102.339 1.00 105.66 ? 526 HIS   A CE1 1 
ATOM   4065 N NE2 . HIS   A 1 501 ? 125.037 125.697 101.348 1.00 107.79 ? 526 HIS   A NE2 1 
ATOM   4066 N N   . THR   A 1 502 ? 131.274 127.487 102.088 1.00 81.80  ? 527 THR   A N   1 
ATOM   4067 C CA  . THR   A 1 502 ? 132.718 127.544 101.926 1.00 77.45  ? 527 THR   A CA  1 
ATOM   4068 C C   . THR   A 1 502 ? 133.389 128.049 103.201 1.00 80.56  ? 527 THR   A C   1 
ATOM   4069 O O   . THR   A 1 502 ? 132.806 128.808 103.978 1.00 82.55  ? 527 THR   A O   1 
ATOM   4070 C CB  . THR   A 1 502 ? 133.076 128.453 100.750 1.00 82.33  ? 527 THR   A CB  1 
ATOM   4071 O OG1 . THR   A 1 502 ? 132.260 128.121 99.621  1.00 86.50  ? 527 THR   A OG1 1 
ATOM   4072 C CG2 . THR   A 1 502 ? 134.532 128.295 100.366 1.00 81.83  ? 527 THR   A CG2 1 
ATOM   4073 N N   . GLU   A 1 503 ? 134.629 127.606 103.413 1.00 76.57  ? 528 GLU   A N   1 
ATOM   4074 C CA  . GLU   A 1 503 ? 135.440 128.026 104.548 1.00 71.03  ? 528 GLU   A CA  1 
ATOM   4075 C C   . GLU   A 1 503 ? 136.859 128.303 104.073 1.00 72.57  ? 528 GLU   A C   1 
ATOM   4076 O O   . GLU   A 1 503 ? 137.316 127.754 103.065 1.00 77.75  ? 528 GLU   A O   1 
ATOM   4077 C CB  . GLU   A 1 503 ? 135.453 126.968 105.654 1.00 70.86  ? 528 GLU   A CB  1 
ATOM   4078 C CG  . GLU   A 1 503 ? 134.082 126.646 106.210 1.00 80.48  ? 528 GLU   A CG  1 
ATOM   4079 C CD  . GLU   A 1 503 ? 134.134 125.625 107.326 1.00 91.84  ? 528 GLU   A CD  1 
ATOM   4080 O OE1 . GLU   A 1 503 ? 135.252 125.239 107.724 1.00 88.84  ? 528 GLU   A OE1 1 
ATOM   4081 O OE2 . GLU   A 1 503 ? 133.059 125.209 107.804 1.00 103.83 ? 528 GLU   A OE2 1 
ATOM   4082 N N   . VAL   A 1 504 ? 137.555 129.159 104.825 1.00 68.56  ? 529 VAL   A N   1 
ATOM   4083 C CA  . VAL   A 1 504 ? 138.881 129.647 104.467 1.00 67.17  ? 529 VAL   A CA  1 
ATOM   4084 C C   . VAL   A 1 504 ? 139.804 129.543 105.674 1.00 70.82  ? 529 VAL   A C   1 
ATOM   4085 O O   . VAL   A 1 504 ? 139.391 129.811 106.807 1.00 74.61  ? 529 VAL   A O   1 
ATOM   4086 C CB  . VAL   A 1 504 ? 138.831 131.099 103.943 1.00 73.17  ? 529 VAL   A CB  1 
ATOM   4087 C CG1 . VAL   A 1 504 ? 138.231 132.049 104.980 1.00 78.43  ? 529 VAL   A CG1 1 
ATOM   4088 C CG2 . VAL   A 1 504 ? 140.217 131.567 103.531 1.00 74.58  ? 529 VAL   A CG2 1 
ATOM   4089 N N   . VAL   A 1 505 ? 141.053 129.148 105.426 1.00 71.73  ? 530 VAL   A N   1 
ATOM   4090 C CA  . VAL   A 1 505 ? 142.098 129.077 106.443 1.00 71.39  ? 530 VAL   A CA  1 
ATOM   4091 C C   . VAL   A 1 505 ? 143.360 129.716 105.879 1.00 74.14  ? 530 VAL   A C   1 
ATOM   4092 O O   . VAL   A 1 505 ? 143.839 129.309 104.816 1.00 79.35  ? 530 VAL   A O   1 
ATOM   4093 C CB  . VAL   A 1 505 ? 142.378 127.626 106.878 1.00 68.44  ? 530 VAL   A CB  1 
ATOM   4094 C CG1 . VAL   A 1 505 ? 143.546 127.577 107.844 1.00 66.95  ? 530 VAL   A CG1 1 
ATOM   4095 C CG2 . VAL   A 1 505 ? 141.136 127.007 107.503 1.00 73.04  ? 530 VAL   A CG2 1 
ATOM   4096 N N   . PHE   A 1 506 ? 143.907 130.695 106.595 1.00 71.23  ? 531 PHE   A N   1 
ATOM   4097 C CA  . PHE   A 1 506 ? 145.076 131.444 106.149 1.00 68.48  ? 531 PHE   A CA  1 
ATOM   4098 C C   . PHE   A 1 506 ? 146.329 130.930 106.846 1.00 70.05  ? 531 PHE   A C   1 
ATOM   4099 O O   . PHE   A 1 506 ? 146.315 130.685 108.056 1.00 73.77  ? 531 PHE   A O   1 
ATOM   4100 C CB  . PHE   A 1 506 ? 144.900 132.935 106.428 1.00 68.32  ? 531 PHE   A CB  1 
ATOM   4101 C CG  . PHE   A 1 506 ? 143.650 133.517 105.840 1.00 73.74  ? 531 PHE   A CG  1 
ATOM   4102 C CD1 . PHE   A 1 506 ? 143.524 133.677 104.475 1.00 75.72  ? 531 PHE   A CD1 1 
ATOM   4103 C CD2 . PHE   A 1 506 ? 142.606 133.910 106.651 1.00 73.74  ? 531 PHE   A CD2 1 
ATOM   4104 C CE1 . PHE   A 1 506 ? 142.379 134.210 103.931 1.00 77.40  ? 531 PHE   A CE1 1 
ATOM   4105 C CE2 . PHE   A 1 506 ? 141.460 134.447 106.111 1.00 74.13  ? 531 PHE   A CE2 1 
ATOM   4106 C CZ  . PHE   A 1 506 ? 141.348 134.596 104.749 1.00 77.16  ? 531 PHE   A CZ  1 
ATOM   4107 N N   . ILE   A 1 507 ? 147.413 130.777 106.081 1.00 68.27  ? 532 ILE   A N   1 
ATOM   4108 C CA  . ILE   A 1 507 ? 148.654 130.182 106.562 1.00 64.27  ? 532 ILE   A CA  1 
ATOM   4109 C C   . ILE   A 1 507 ? 149.820 131.064 106.138 1.00 67.36  ? 532 ILE   A C   1 
ATOM   4110 O O   . ILE   A 1 507 ? 149.824 131.617 105.032 1.00 76.16  ? 532 ILE   A O   1 
ATOM   4111 C CB  . ILE   A 1 507 ? 148.848 128.748 106.024 1.00 70.38  ? 532 ILE   A CB  1 
ATOM   4112 C CG1 . ILE   A 1 507 ? 147.661 127.841 106.383 1.00 75.00  ? 532 ILE   A CG1 1 
ATOM   4113 C CG2 . ILE   A 1 507 ? 150.151 128.161 106.536 1.00 71.42  ? 532 ILE   A CG2 1 
ATOM   4114 C CD1 . ILE   A 1 507 ? 147.463 127.586 107.869 1.00 72.92  ? 532 ILE   A CD1 1 
ATOM   4115 N N   . ALA   A 1 508 ? 150.802 131.203 107.030 1.00 64.80  ? 533 ALA   A N   1 
ATOM   4116 C CA  . ALA   A 1 508 ? 152.052 131.903 106.753 1.00 61.30  ? 533 ALA   A CA  1 
ATOM   4117 C C   . ALA   A 1 508 ? 153.198 131.009 107.192 1.00 61.60  ? 533 ALA   A C   1 
ATOM   4118 O O   . ALA   A 1 508 ? 153.252 130.602 108.357 1.00 68.05  ? 533 ALA   A O   1 
ATOM   4119 C CB  . ALA   A 1 508 ? 152.111 133.249 107.476 1.00 62.39  ? 533 ALA   A CB  1 
ATOM   4120 N N   . ASP   A 1 509 ? 154.112 130.712 106.269 1.00 66.00  ? 534 ASP   A N   1 
ATOM   4121 C CA  . ASP   A 1 509 ? 155.142 129.703 106.469 1.00 68.00  ? 534 ASP   A CA  1 
ATOM   4122 C C   . ASP   A 1 509 ? 156.520 130.305 106.241 1.00 71.74  ? 534 ASP   A C   1 
ATOM   4123 O O   . ASP   A 1 509 ? 156.698 131.212 105.421 1.00 75.24  ? 534 ASP   A O   1 
ATOM   4124 C CB  . ASP   A 1 509 ? 154.934 128.510 105.530 1.00 71.05  ? 534 ASP   A CB  1 
ATOM   4125 C CG  . ASP   A 1 509 ? 155.739 127.292 105.941 1.00 78.96  ? 534 ASP   A CG  1 
ATOM   4126 O OD1 . ASP   A 1 509 ? 156.513 127.380 106.916 1.00 77.39  ? 534 ASP   A OD1 1 
ATOM   4127 O OD2 . ASP   A 1 509 ? 155.593 126.240 105.285 1.00 78.97  ? 534 ASP   A OD2 1 
ATOM   4128 N N   . PHE   A 1 510 ? 157.491 129.779 106.985 1.00 72.91  ? 535 PHE   A N   1 
ATOM   4129 C CA  . PHE   A 1 510 ? 158.855 130.277 106.991 1.00 69.05  ? 535 PHE   A CA  1 
ATOM   4130 C C   . PHE   A 1 510 ? 159.666 129.674 105.845 1.00 68.85  ? 535 PHE   A C   1 
ATOM   4131 O O   . PHE   A 1 510 ? 159.288 128.644 105.282 1.00 72.78  ? 535 PHE   A O   1 
ATOM   4132 C CB  . PHE   A 1 510 ? 159.516 129.945 108.324 1.00 67.38  ? 535 PHE   A CB  1 
ATOM   4133 C CG  . PHE   A 1 510 ? 158.996 130.751 109.473 1.00 66.28  ? 535 PHE   A CG  1 
ATOM   4134 C CD1 . PHE   A 1 510 ? 159.567 131.965 109.796 1.00 67.79  ? 535 PHE   A CD1 1 
ATOM   4135 C CD2 . PHE   A 1 510 ? 157.939 130.294 110.232 1.00 67.69  ? 535 PHE   A CD2 1 
ATOM   4136 C CE1 . PHE   A 1 510 ? 159.093 132.705 110.850 1.00 68.02  ? 535 PHE   A CE1 1 
ATOM   4137 C CE2 . PHE   A 1 510 ? 157.462 131.032 111.288 1.00 67.15  ? 535 PHE   A CE2 1 
ATOM   4138 C CZ  . PHE   A 1 510 ? 158.038 132.239 111.597 1.00 68.75  ? 535 PHE   A CZ  1 
ATOM   4139 N N   . PRO   A 1 511 ? 160.789 130.294 105.477 1.00 67.26  ? 536 PRO   A N   1 
ATOM   4140 C CA  . PRO   A 1 511 ? 161.604 129.736 104.393 1.00 68.58  ? 536 PRO   A CA  1 
ATOM   4141 C C   . PRO   A 1 511 ? 162.341 128.479 104.822 1.00 68.29  ? 536 PRO   A C   1 
ATOM   4142 O O   . PRO   A 1 511 ? 162.884 128.401 105.926 1.00 69.04  ? 536 PRO   A O   1 
ATOM   4143 C CB  . PRO   A 1 511 ? 162.579 130.870 104.066 1.00 71.03  ? 536 PRO   A CB  1 
ATOM   4144 C CG  . PRO   A 1 511 ? 162.689 131.634 105.317 1.00 72.51  ? 536 PRO   A CG  1 
ATOM   4145 C CD  . PRO   A 1 511 ? 161.323 131.593 105.929 1.00 71.66  ? 536 PRO   A CD  1 
ATOM   4146 N N   . GLY   A 1 512 ? 162.352 127.491 103.930 1.00 70.60  ? 537 GLY   A N   1 
ATOM   4147 C CA  . GLY   A 1 512 ? 163.056 126.245 104.164 1.00 69.97  ? 537 GLY   A CA  1 
ATOM   4148 C C   . GLY   A 1 512 ? 162.133 125.131 104.605 1.00 72.28  ? 537 GLY   A C   1 
ATOM   4149 O O   . GLY   A 1 512 ? 162.295 123.979 104.196 1.00 77.51  ? 537 GLY   A O   1 
ATOM   4150 N N   . LEU   A 1 513 ? 161.157 125.467 105.439 1.00 71.38  ? 538 LEU   A N   1 
ATOM   4151 C CA  . LEU   A 1 513 ? 160.238 124.481 105.978 1.00 68.68  ? 538 LEU   A CA  1 
ATOM   4152 C C   . LEU   A 1 513 ? 159.208 124.086 104.923 1.00 73.83  ? 538 LEU   A C   1 
ATOM   4153 O O   . LEU   A 1 513 ? 159.089 124.709 103.866 1.00 78.42  ? 538 LEU   A O   1 
ATOM   4154 C CB  . LEU   A 1 513 ? 159.542 125.026 107.226 1.00 71.63  ? 538 LEU   A CB  1 
ATOM   4155 C CG  . LEU   A 1 513 ? 160.342 125.058 108.532 1.00 73.20  ? 538 LEU   A CG  1 
ATOM   4156 C CD1 . LEU   A 1 513 ? 161.532 125.996 108.453 1.00 73.01  ? 538 LEU   A CD1 1 
ATOM   4157 C CD2 . LEU   A 1 513 ? 159.435 125.456 109.682 1.00 73.64  ? 538 LEU   A CD2 1 
ATOM   4158 N N   . HIS   A 1 514 ? 158.462 123.024 105.220 1.00 74.41  ? 539 HIS   A N   1 
ATOM   4159 C CA  . HIS   A 1 514 ? 157.404 122.545 104.345 1.00 72.19  ? 539 HIS   A CA  1 
ATOM   4160 C C   . HIS   A 1 514 ? 156.265 122.001 105.190 1.00 72.99  ? 539 HIS   A C   1 
ATOM   4161 O O   . HIS   A 1 514 ? 156.470 121.554 106.320 1.00 75.56  ? 539 HIS   A O   1 
ATOM   4162 C CB  . HIS   A 1 514 ? 157.912 121.461 103.386 1.00 73.35  ? 539 HIS   A CB  1 
ATOM   4163 C CG  . HIS   A 1 514 ? 158.348 120.203 104.069 1.00 70.28  ? 539 HIS   A CG  1 
ATOM   4164 N ND1 . HIS   A 1 514 ? 157.461 119.229 104.471 1.00 70.62  ? 539 HIS   A ND1 1 
ATOM   4165 C CD2 . HIS   A 1 514 ? 159.577 119.757 104.414 1.00 74.12  ? 539 HIS   A CD2 1 
ATOM   4166 C CE1 . HIS   A 1 514 ? 158.125 118.238 105.038 1.00 76.87  ? 539 HIS   A CE1 1 
ATOM   4167 N NE2 . HIS   A 1 514 ? 159.411 118.534 105.016 1.00 78.71  ? 539 HIS   A NE2 1 
ATOM   4168 N N   . LEU   A 1 515 ? 155.059 122.047 104.626 1.00 74.22  ? 540 LEU   A N   1 
ATOM   4169 C CA  . LEU   A 1 515 ? 153.860 121.517 105.264 1.00 72.04  ? 540 LEU   A CA  1 
ATOM   4170 C C   . LEU   A 1 515 ? 153.326 120.357 104.438 1.00 76.34  ? 540 LEU   A C   1 
ATOM   4171 O O   . LEU   A 1 515 ? 153.061 120.517 103.242 1.00 80.26  ? 540 LEU   A O   1 
ATOM   4172 C CB  . LEU   A 1 515 ? 152.798 122.610 105.418 1.00 68.14  ? 540 LEU   A CB  1 
ATOM   4173 C CG  . LEU   A 1 515 ? 151.327 122.229 105.604 1.00 71.24  ? 540 LEU   A CG  1 
ATOM   4174 C CD1 . LEU   A 1 515 ? 151.131 121.389 106.849 1.00 73.57  ? 540 LEU   A CD1 1 
ATOM   4175 C CD2 . LEU   A 1 515 ? 150.483 123.479 105.677 1.00 69.95  ? 540 LEU   A CD2 1 
ATOM   4176 N N   . GLU   A 1 516 ? 153.173 119.210 105.077 1.00 73.33  ? 541 GLU   A N   1 
ATOM   4177 C CA  . GLU   A 1 516 ? 152.609 118.013 104.467 1.00 71.28  ? 541 GLU   A CA  1 
ATOM   4178 C C   . GLU   A 1 516 ? 151.192 117.824 104.985 1.00 72.48  ? 541 GLU   A C   1 
ATOM   4179 O O   . GLU   A 1 516 ? 150.978 117.780 106.199 1.00 79.13  ? 541 GLU   A O   1 
ATOM   4180 C CB  . GLU   A 1 516 ? 153.464 116.786 104.789 1.00 73.94  ? 541 GLU   A CB  1 
ATOM   4181 C CG  . GLU   A 1 516 ? 152.994 115.492 104.136 1.00 81.79  ? 541 GLU   A CG  1 
ATOM   4182 C CD  . GLU   A 1 516 ? 153.891 114.317 104.467 1.00 92.33  ? 541 GLU   A CD  1 
ATOM   4183 O OE1 . GLU   A 1 516 ? 155.128 114.474 104.396 1.00 92.18  ? 541 GLU   A OE1 1 
ATOM   4184 O OE2 . GLU   A 1 516 ? 153.360 113.237 104.801 1.00 96.88  ? 541 GLU   A OE2 1 
ATOM   4185 N N   . ASN   A 1 517 ? 150.222 117.700 104.071 1.00 70.12  ? 542 ASN   A N   1 
ATOM   4186 C CA  . ASN   A 1 517 ? 148.808 117.665 104.411 1.00 69.81  ? 542 ASN   A CA  1 
ATOM   4187 C C   . ASN   A 1 517 ? 148.120 116.525 103.671 1.00 72.19  ? 542 ASN   A C   1 
ATOM   4188 O O   . ASN   A 1 517 ? 148.553 116.104 102.592 1.00 76.26  ? 542 ASN   A O   1 
ATOM   4189 C CB  . ASN   A 1 517 ? 148.142 119.003 104.072 1.00 72.87  ? 542 ASN   A CB  1 
ATOM   4190 C CG  . ASN   A 1 517 ? 146.705 119.074 104.529 1.00 81.27  ? 542 ASN   A CG  1 
ATOM   4191 O OD1 . ASN   A 1 517 ? 146.272 118.293 105.375 1.00 86.03  ? 542 ASN   A OD1 1 
ATOM   4192 N ND2 . ASN   A 1 517 ? 145.953 120.015 103.972 1.00 81.70  ? 542 ASN   A ND2 1 
ATOM   4193 N N   . PHE   A 1 518 ? 147.043 116.025 104.280 1.00 73.31  ? 543 PHE   A N   1 
ATOM   4194 C CA  . PHE   A 1 518 ? 146.244 114.918 103.754 1.00 72.85  ? 543 PHE   A CA  1 
ATOM   4195 C C   . PHE   A 1 518 ? 144.788 115.371 103.716 1.00 77.11  ? 543 PHE   A C   1 
ATOM   4196 O O   . PHE   A 1 518 ? 144.094 115.332 104.736 1.00 80.47  ? 543 PHE   A O   1 
ATOM   4197 C CB  . PHE   A 1 518 ? 146.416 113.670 104.611 1.00 69.84  ? 543 PHE   A CB  1 
ATOM   4198 C CG  . PHE   A 1 518 ? 145.464 112.562 104.271 1.00 72.50  ? 543 PHE   A CG  1 
ATOM   4199 C CD1 . PHE   A 1 518 ? 145.697 111.740 103.185 1.00 73.78  ? 543 PHE   A CD1 1 
ATOM   4200 C CD2 . PHE   A 1 518 ? 144.345 112.329 105.047 1.00 71.15  ? 543 PHE   A CD2 1 
ATOM   4201 C CE1 . PHE   A 1 518 ? 144.828 110.719 102.873 1.00 69.18  ? 543 PHE   A CE1 1 
ATOM   4202 C CE2 . PHE   A 1 518 ? 143.473 111.311 104.738 1.00 69.65  ? 543 PHE   A CE2 1 
ATOM   4203 C CZ  . PHE   A 1 518 ? 143.716 110.504 103.651 1.00 68.78  ? 543 PHE   A CZ  1 
ATOM   4204 N N   . VAL   A 1 519 ? 144.329 115.812 102.546 1.00 74.94  ? 544 VAL   A N   1 
ATOM   4205 C CA  . VAL   A 1 519 ? 142.942 116.234 102.396 1.00 69.87  ? 544 VAL   A CA  1 
ATOM   4206 C C   . VAL   A 1 519 ? 142.040 115.012 102.481 1.00 70.71  ? 544 VAL   A C   1 
ATOM   4207 O O   . VAL   A 1 519 ? 142.217 114.036 101.741 1.00 76.38  ? 544 VAL   A O   1 
ATOM   4208 C CB  . VAL   A 1 519 ? 142.743 116.982 101.069 1.00 70.98  ? 544 VAL   A CB  1 
ATOM   4209 C CG1 . VAL   A 1 519 ? 141.318 117.522 100.966 1.00 72.85  ? 544 VAL   A CG1 1 
ATOM   4210 C CG2 . VAL   A 1 519 ? 143.758 118.109 100.932 1.00 73.55  ? 544 VAL   A CG2 1 
ATOM   4211 N N   . SER   A 1 520 ? 141.066 115.059 103.384 1.00 71.19  ? 545 SER   A N   1 
ATOM   4212 C CA  . SER   A 1 520 ? 140.151 113.942 103.552 1.00 73.36  ? 545 SER   A CA  1 
ATOM   4213 C C   . SER   A 1 520 ? 139.272 113.780 102.316 1.00 80.08  ? 545 SER   A C   1 
ATOM   4214 O O   . SER   A 1 520 ? 139.053 114.719 101.546 1.00 86.51  ? 545 SER   A O   1 
ATOM   4215 C CB  . SER   A 1 520 ? 139.279 114.145 104.787 1.00 78.43  ? 545 SER   A CB  1 
ATOM   4216 O OG  . SER   A 1 520 ? 138.453 115.283 104.637 1.00 82.50  ? 545 SER   A OG  1 
ATOM   4217 N N   . GLU   A 1 521 ? 138.775 112.555 102.125 1.00 79.99  ? 546 GLU   A N   1 
ATOM   4218 C CA  . GLU   A 1 521 ? 137.934 112.269 100.967 1.00 82.05  ? 546 GLU   A CA  1 
ATOM   4219 C C   . GLU   A 1 521 ? 136.661 113.103 100.974 1.00 80.83  ? 546 GLU   A C   1 
ATOM   4220 O O   . GLU   A 1 521 ? 136.135 113.440 99.908  1.00 79.35  ? 546 GLU   A O   1 
ATOM   4221 C CB  . GLU   A 1 521 ? 137.586 110.781 100.928 1.00 84.92  ? 546 GLU   A CB  1 
ATOM   4222 C CG  . GLU   A 1 521 ? 138.791 109.864 100.840 1.00 92.36  ? 546 GLU   A CG  1 
ATOM   4223 C CD  . GLU   A 1 521 ? 138.405 108.400 100.763 1.00 101.12 ? 546 GLU   A CD  1 
ATOM   4224 O OE1 . GLU   A 1 521 ? 137.192 108.103 100.771 1.00 103.15 ? 546 GLU   A OE1 1 
ATOM   4225 O OE2 . GLU   A 1 521 ? 139.314 107.547 100.696 1.00 101.74 ? 546 GLU   A OE2 1 
ATOM   4226 N N   . ASP   A 1 522 ? 136.147 113.436 102.159 1.00 80.46  ? 547 ASP   A N   1 
ATOM   4227 C CA  . ASP   A 1 522 ? 134.920 114.219 102.241 1.00 80.67  ? 547 ASP   A CA  1 
ATOM   4228 C C   . ASP   A 1 522 ? 135.114 115.620 101.676 1.00 79.70  ? 547 ASP   A C   1 
ATOM   4229 O O   . ASP   A 1 522 ? 134.219 116.157 101.014 1.00 82.27  ? 547 ASP   A O   1 
ATOM   4230 C CB  . ASP   A 1 522 ? 134.443 114.289 103.690 1.00 84.97  ? 547 ASP   A CB  1 
ATOM   4231 C CG  . ASP   A 1 522 ? 134.168 112.921 104.278 1.00 94.39  ? 547 ASP   A CG  1 
ATOM   4232 O OD1 . ASP   A 1 522 ? 133.807 112.004 103.511 1.00 95.28  ? 547 ASP   A OD1 1 
ATOM   4233 O OD2 . ASP   A 1 522 ? 134.313 112.760 105.508 1.00 96.79  ? 547 ASP   A OD2 1 
ATOM   4234 N N   . LEU   A 1 523 ? 136.274 116.229 101.923 1.00 78.89  ? 548 LEU   A N   1 
ATOM   4235 C CA  . LEU   A 1 523 ? 136.519 117.620 101.540 1.00 75.67  ? 548 LEU   A CA  1 
ATOM   4236 C C   . LEU   A 1 523 ? 136.832 117.694 100.044 1.00 78.65  ? 548 LEU   A C   1 
ATOM   4237 O O   . LEU   A 1 523 ? 137.964 117.921 99.610  1.00 80.96  ? 548 LEU   A O   1 
ATOM   4238 C CB  . LEU   A 1 523 ? 137.638 118.220 102.383 1.00 70.75  ? 548 LEU   A CB  1 
ATOM   4239 C CG  . LEU   A 1 523 ? 137.227 118.935 103.670 1.00 73.32  ? 548 LEU   A CG  1 
ATOM   4240 C CD1 . LEU   A 1 523 ? 136.608 117.994 104.695 1.00 80.86  ? 548 LEU   A CD1 1 
ATOM   4241 C CD2 . LEU   A 1 523 ? 138.426 119.641 104.265 1.00 75.70  ? 548 LEU   A CD2 1 
ATOM   4242 N N   . GLY   A 1 524 ? 135.791 117.481 99.245  1.00 76.99  ? 549 GLY   A N   1 
ATOM   4243 C CA  . GLY   A 1 524 ? 135.893 117.746 97.828  1.00 74.24  ? 549 GLY   A CA  1 
ATOM   4244 C C   . GLY   A 1 524 ? 135.851 119.231 97.529  1.00 78.31  ? 549 GLY   A C   1 
ATOM   4245 O O   . GLY   A 1 524 ? 135.360 120.042 98.314  1.00 83.75  ? 549 GLY   A O   1 
ATOM   4246 N N   . ASN   A 1 525 ? 136.374 119.597 96.354  1.00 74.65  ? 550 ASN   A N   1 
ATOM   4247 C CA  . ASN   A 1 525 ? 136.440 120.987 95.907  1.00 74.91  ? 550 ASN   A CA  1 
ATOM   4248 C C   . ASN   A 1 525 ? 137.241 121.842 96.893  1.00 74.86  ? 550 ASN   A C   1 
ATOM   4249 O O   . ASN   A 1 525 ? 136.747 122.816 97.463  1.00 74.51  ? 550 ASN   A O   1 
ATOM   4250 C CB  . ASN   A 1 525 ? 135.034 121.557 95.695  1.00 76.87  ? 550 ASN   A CB  1 
ATOM   4251 C CG  . ASN   A 1 525 ? 135.052 122.944 95.082  1.00 81.66  ? 550 ASN   A CG  1 
ATOM   4252 O OD1 . ASN   A 1 525 ? 135.476 123.120 93.941  1.00 83.67  ? 550 ASN   A OD1 1 
ATOM   4253 N ND2 . ASN   A 1 525 ? 134.582 123.933 95.831  1.00 84.37  ? 550 ASN   A ND2 1 
ATOM   4254 N N   . THR   A 1 526 ? 138.500 121.437 97.092  1.00 73.74  ? 551 THR   A N   1 
ATOM   4255 C CA  . THR   A 1 526 ? 139.464 122.167 97.906  1.00 71.93  ? 551 THR   A CA  1 
ATOM   4256 C C   . THR   A 1 526 ? 140.482 122.828 96.988  1.00 77.74  ? 551 THR   A C   1 
ATOM   4257 O O   . THR   A 1 526 ? 141.003 122.183 96.072  1.00 82.59  ? 551 THR   A O   1 
ATOM   4258 C CB  . THR   A 1 526 ? 140.170 121.233 98.890  1.00 72.04  ? 551 THR   A CB  1 
ATOM   4259 O OG1 . THR   A 1 526 ? 139.204 120.623 99.753  1.00 77.25  ? 551 THR   A OG1 1 
ATOM   4260 C CG2 . THR   A 1 526 ? 141.183 121.997 99.725  1.00 73.12  ? 551 THR   A CG2 1 
ATOM   4261 N N   . SER   A 1 527 ? 140.761 124.108 97.234  1.00 75.72  ? 552 SER   A N   1 
ATOM   4262 C CA  . SER   A 1 527 ? 141.638 124.904 96.387  1.00 70.16  ? 552 SER   A CA  1 
ATOM   4263 C C   . SER   A 1 527 ? 142.666 125.633 97.238  1.00 71.89  ? 552 SER   A C   1 
ATOM   4264 O O   . SER   A 1 527 ? 142.414 125.956 98.401  1.00 78.59  ? 552 SER   A O   1 
ATOM   4265 C CB  . SER   A 1 527 ? 140.843 125.923 95.566  1.00 75.85  ? 552 SER   A CB  1 
ATOM   4266 O OG  . SER   A 1 527 ? 140.159 126.832 96.410  1.00 80.30  ? 552 SER   A OG  1 
ATOM   4267 N N   . ILE   A 1 528 ? 143.829 125.885 96.639  1.00 71.97  ? 553 ILE   A N   1 
ATOM   4268 C CA  . ILE   A 1 528 ? 144.928 126.601 97.279  1.00 72.67  ? 553 ILE   A CA  1 
ATOM   4269 C C   . ILE   A 1 528 ? 145.247 127.832 96.443  1.00 76.41  ? 553 ILE   A C   1 
ATOM   4270 O O   . ILE   A 1 528 ? 145.392 127.738 95.218  1.00 81.09  ? 553 ILE   A O   1 
ATOM   4271 C CB  . ILE   A 1 528 ? 146.174 125.709 97.453  1.00 71.30  ? 553 ILE   A CB  1 
ATOM   4272 C CG1 . ILE   A 1 528 ? 147.250 126.448 98.252  1.00 71.10  ? 553 ILE   A CG1 1 
ATOM   4273 C CG2 . ILE   A 1 528 ? 146.731 125.248 96.109  1.00 75.20  ? 553 ILE   A CG2 1 
ATOM   4274 C CD1 . ILE   A 1 528 ? 148.408 125.574 98.664  1.00 75.85  ? 553 ILE   A CD1 1 
ATOM   4275 N N   . GLN   A 1 529 ? 145.342 128.984 97.108  1.00 75.71  ? 554 GLN   A N   1 
ATOM   4276 C CA  . GLN   A 1 529 ? 145.650 130.256 96.472  1.00 73.42  ? 554 GLN   A CA  1 
ATOM   4277 C C   . GLN   A 1 529 ? 146.787 130.927 97.224  1.00 74.85  ? 554 GLN   A C   1 
ATOM   4278 O O   . GLN   A 1 529 ? 146.872 130.830 98.451  1.00 80.52  ? 554 GLN   A O   1 
ATOM   4279 C CB  . GLN   A 1 529 ? 144.423 131.166 96.447  1.00 78.16  ? 554 GLN   A CB  1 
ATOM   4280 C CG  . GLN   A 1 529 ? 144.601 132.424 95.624  1.00 84.19  ? 554 GLN   A CG  1 
ATOM   4281 C CD  . GLN   A 1 529 ? 143.310 133.198 95.467  1.00 90.76  ? 554 GLN   A CD  1 
ATOM   4282 O OE1 . GLN   A 1 529 ? 142.272 132.807 95.999  1.00 88.92  ? 554 GLN   A OE1 1 
ATOM   4283 N NE2 . GLN   A 1 529 ? 143.367 134.301 94.731  1.00 92.57  ? 554 GLN   A NE2 1 
ATOM   4284 N N   . LEU   A 1 530 ? 147.652 131.614 96.483  1.00 74.11  ? 555 LEU   A N   1 
ATOM   4285 C CA  . LEU   A 1 530 ? 148.845 132.247 97.028  1.00 74.35  ? 555 LEU   A CA  1 
ATOM   4286 C C   . LEU   A 1 530 ? 148.627 133.750 97.106  1.00 80.01  ? 555 LEU   A C   1 
ATOM   4287 O O   . LEU   A 1 530 ? 148.206 134.370 96.123  1.00 88.22  ? 555 LEU   A O   1 
ATOM   4288 C CB  . LEU   A 1 530 ? 150.067 131.930 96.163  1.00 76.00  ? 555 LEU   A CB  1 
ATOM   4289 C CG  . LEU   A 1 530 ? 151.423 132.496 96.588  1.00 76.03  ? 555 LEU   A CG  1 
ATOM   4290 C CD1 . LEU   A 1 530 ? 151.850 131.939 97.933  1.00 77.18  ? 555 LEU   A CD1 1 
ATOM   4291 C CD2 . LEU   A 1 530 ? 152.469 132.201 95.522  1.00 81.30  ? 555 LEU   A CD2 1 
ATOM   4292 N N   . LEU   A 1 531 ? 148.917 134.329 98.270  1.00 75.45  ? 556 LEU   A N   1 
ATOM   4293 C CA  . LEU   A 1 531 ? 148.770 135.760 98.502  1.00 69.76  ? 556 LEU   A CA  1 
ATOM   4294 C C   . LEU   A 1 531 ? 150.090 136.514 98.433  1.00 76.43  ? 556 LEU   A C   1 
ATOM   4295 O O   . LEU   A 1 531 ? 150.135 137.611 97.870  1.00 80.83  ? 556 LEU   A O   1 
ATOM   4296 C CB  . LEU   A 1 531 ? 148.119 136.009 99.865  1.00 68.30  ? 556 LEU   A CB  1 
ATOM   4297 C CG  . LEU   A 1 531 ? 146.679 135.525 100.039 1.00 72.70  ? 556 LEU   A CG  1 
ATOM   4298 C CD1 . LEU   A 1 531 ? 146.240 135.691 101.479 1.00 73.66  ? 556 LEU   A CD1 1 
ATOM   4299 C CD2 . LEU   A 1 531 ? 145.733 136.269 99.113  1.00 73.32  ? 556 LEU   A CD2 1 
ATOM   4300 N N   . GLN   A 1 532 ? 151.167 135.966 98.993  1.00 81.21  ? 557 GLN   A N   1 
ATOM   4301 C CA  . GLN   A 1 532 ? 152.463 136.631 98.932  1.00 79.39  ? 557 GLN   A CA  1 
ATOM   4302 C C   . GLN   A 1 532 ? 153.576 135.599 99.023  1.00 84.38  ? 557 GLN   A C   1 
ATOM   4303 O O   . GLN   A 1 532 ? 153.444 134.596 99.728  1.00 86.99  ? 557 GLN   A O   1 
ATOM   4304 C CB  . GLN   A 1 532 ? 152.614 137.666 100.052 1.00 78.74  ? 557 GLN   A CB  1 
ATOM   4305 C CG  . GLN   A 1 532 ? 153.901 138.475 99.980  1.00 82.31  ? 557 GLN   A CG  1 
ATOM   4306 C CD  . GLN   A 1 532 ? 153.957 139.576 101.014 1.00 86.16  ? 557 GLN   A CD  1 
ATOM   4307 O OE1 . GLN   A 1 532 ? 152.943 139.938 101.609 1.00 81.11  ? 557 GLN   A OE1 1 
ATOM   4308 N NE2 . GLN   A 1 532 ? 155.149 140.116 101.237 1.00 89.97  ? 557 GLN   A NE2 1 
ATOM   4309 N N   . GLY   A 1 533 ? 154.667 135.862 98.316  1.00 85.98  ? 558 GLY   A N   1 
ATOM   4310 C CA  . GLY   A 1 533 ? 155.843 135.017 98.350  1.00 84.86  ? 558 GLY   A CA  1 
ATOM   4311 C C   . GLY   A 1 533 ? 155.942 134.097 97.151  1.00 83.22  ? 558 GLY   A C   1 
ATOM   4312 O O   . GLY   A 1 533 ? 155.380 134.343 96.081  1.00 85.47  ? 558 GLY   A O   1 
ATOM   4313 N N   . GLU   A 1 534 ? 156.691 133.011 97.344  1.00 82.84  ? 559 GLU   A N   1 
ATOM   4314 C CA  . GLU   A 1 534 ? 156.882 131.989 96.320  1.00 86.76  ? 559 GLU   A CA  1 
ATOM   4315 C C   . GLU   A 1 534 ? 156.827 130.625 96.987  1.00 86.00  ? 559 GLU   A C   1 
ATOM   4316 O O   . GLU   A 1 534 ? 157.597 130.360 97.915  1.00 85.45  ? 559 GLU   A O   1 
ATOM   4317 C CB  . GLU   A 1 534 ? 158.214 132.179 95.590  1.00 88.58  ? 559 GLU   A CB  1 
ATOM   4318 C CG  . GLU   A 1 534 ? 158.414 131.244 94.411  1.00 93.65  ? 559 GLU   A CG  1 
ATOM   4319 C CD  . GLU   A 1 534 ? 159.701 131.518 93.661  1.00 102.29 ? 559 GLU   A CD  1 
ATOM   4320 O OE1 . GLU   A 1 534 ? 160.437 132.445 94.059  1.00 104.48 ? 559 GLU   A OE1 1 
ATOM   4321 O OE2 . GLU   A 1 534 ? 159.978 130.805 92.673  1.00 106.00 ? 559 GLU   A OE2 1 
ATOM   4322 N N   . VAL   A 1 535 ? 155.920 129.768 96.515  1.00 83.02  ? 560 VAL   A N   1 
ATOM   4323 C CA  . VAL   A 1 535 ? 155.731 128.431 97.059  1.00 77.25  ? 560 VAL   A CA  1 
ATOM   4324 C C   . VAL   A 1 535 ? 155.708 127.434 95.910  1.00 78.24  ? 560 VAL   A C   1 
ATOM   4325 O O   . VAL   A 1 535 ? 155.509 127.793 94.747  1.00 85.82  ? 560 VAL   A O   1 
ATOM   4326 C CB  . VAL   A 1 535 ? 154.436 128.313 97.893  1.00 75.67  ? 560 VAL   A CB  1 
ATOM   4327 C CG1 . VAL   A 1 535 ? 154.401 129.379 98.970  1.00 76.96  ? 560 VAL   A CG1 1 
ATOM   4328 C CG2 . VAL   A 1 535 ? 153.209 128.405 97.004  1.00 79.12  ? 560 VAL   A CG2 1 
ATOM   4329 N N   . THR   A 1 536 ? 155.938 126.168 96.252  1.00 77.17  ? 561 THR   A N   1 
ATOM   4330 C CA  . THR   A 1 536 ? 155.835 125.062 95.305  1.00 79.47  ? 561 THR   A CA  1 
ATOM   4331 C C   . THR   A 1 536 ? 154.955 123.983 95.914  1.00 81.83  ? 561 THR   A C   1 
ATOM   4332 O O   . THR   A 1 536 ? 155.219 123.521 97.029  1.00 83.80  ? 561 THR   A O   1 
ATOM   4333 C CB  . THR   A 1 536 ? 157.210 124.493 94.948  1.00 79.31  ? 561 THR   A CB  1 
ATOM   4334 O OG1 . THR   A 1 536 ? 157.736 123.768 96.063  1.00 85.19  ? 561 THR   A OG1 1 
ATOM   4335 C CG2 . THR   A 1 536 ? 158.170 125.608 94.575  1.00 81.16  ? 561 THR   A CG2 1 
ATOM   4336 N N   . VAL   A 1 537 ? 153.914 123.590 95.183  1.00 78.34  ? 562 VAL   A N   1 
ATOM   4337 C CA  . VAL   A 1 537 ? 152.954 122.587 95.633  1.00 75.66  ? 562 VAL   A CA  1 
ATOM   4338 C C   . VAL   A 1 537 ? 153.257 121.282 94.917  1.00 79.69  ? 562 VAL   A C   1 
ATOM   4339 O O   . VAL   A 1 537 ? 153.330 121.247 93.683  1.00 84.97  ? 562 VAL   A O   1 
ATOM   4340 C CB  . VAL   A 1 537 ? 151.509 123.038 95.367  1.00 82.13  ? 562 VAL   A CB  1 
ATOM   4341 C CG1 . VAL   A 1 537 ? 150.528 121.957 95.801  1.00 83.88  ? 562 VAL   A CG1 1 
ATOM   4342 C CG2 . VAL   A 1 537 ? 151.222 124.354 96.080  1.00 82.36  ? 562 VAL   A CG2 1 
ATOM   4343 N N   . GLU   A 1 538 ? 153.425 120.211 95.692  1.00 82.85  ? 563 GLU   A N   1 
ATOM   4344 C CA  . GLU   A 1 538 ? 153.837 118.904 95.198  1.00 81.82  ? 563 GLU   A CA  1 
ATOM   4345 C C   . GLU   A 1 538 ? 152.761 117.877 95.506  1.00 84.27  ? 563 GLU   A C   1 
ATOM   4346 O O   . GLU   A 1 538 ? 152.327 117.751 96.657  1.00 85.98  ? 563 GLU   A O   1 
ATOM   4347 C CB  . GLU   A 1 538 ? 155.164 118.475 95.831  1.00 82.84  ? 563 GLU   A CB  1 
ATOM   4348 C CG  . GLU   A 1 538 ? 155.615 117.064 95.459  1.00 86.78  ? 563 GLU   A CG  1 
ATOM   4349 C CD  . GLU   A 1 538 ? 157.036 116.762 95.897  1.00 93.60  ? 563 GLU   A CD  1 
ATOM   4350 O OE1 . GLU   A 1 538 ? 157.726 117.683 96.383  1.00 94.61  ? 563 GLU   A OE1 1 
ATOM   4351 O OE2 . GLU   A 1 538 ? 157.465 115.597 95.758  1.00 93.92  ? 563 GLU   A OE2 1 
ATOM   4352 N N   . LEU   A 1 539 ? 152.339 117.148 94.476  1.00 87.18  ? 564 LEU   A N   1 
ATOM   4353 C CA  . LEU   A 1 539 ? 151.481 115.982 94.621  1.00 84.09  ? 564 LEU   A CA  1 
ATOM   4354 C C   . LEU   A 1 539 ? 152.361 114.740 94.559  1.00 92.10  ? 564 LEU   A C   1 
ATOM   4355 O O   . LEU   A 1 539 ? 153.072 114.525 93.566  1.00 98.82  ? 564 LEU   A O   1 
ATOM   4356 C CB  . LEU   A 1 539 ? 150.417 115.946 93.527  1.00 80.23  ? 564 LEU   A CB  1 
ATOM   4357 C CG  . LEU   A 1 539 ? 149.543 117.190 93.384  1.00 82.14  ? 564 LEU   A CG  1 
ATOM   4358 C CD1 . LEU   A 1 539 ? 148.562 117.006 92.243  1.00 84.75  ? 564 LEU   A CD1 1 
ATOM   4359 C CD2 . LEU   A 1 539 ? 148.806 117.496 94.676  1.00 83.58  ? 564 LEU   A CD2 1 
ATOM   4360 N N   . VAL   A 1 540 ? 152.321 113.936 95.626  1.00 88.60  ? 565 VAL   A N   1 
ATOM   4361 C CA  . VAL   A 1 540 ? 153.158 112.741 95.713  1.00 86.14  ? 565 VAL   A CA  1 
ATOM   4362 C C   . VAL   A 1 540 ? 152.558 111.540 95.004  1.00 84.52  ? 565 VAL   A C   1 
ATOM   4363 O O   . VAL   A 1 540 ? 153.257 110.536 94.818  1.00 88.38  ? 565 VAL   A O   1 
ATOM   4364 C CB  . VAL   A 1 540 ? 153.437 112.357 97.180  1.00 82.41  ? 565 VAL   A CB  1 
ATOM   4365 C CG1 . VAL   A 1 540 ? 154.046 113.528 97.934  1.00 84.25  ? 565 VAL   A CG1 1 
ATOM   4366 C CG2 . VAL   A 1 540 ? 152.174 111.863 97.875  1.00 80.80  ? 565 VAL   A CG2 1 
ATOM   4367 N N   . ALA   A 1 541 ? 151.283 111.601 94.616  1.00 83.40  ? 566 ALA   A N   1 
ATOM   4368 C CA  . ALA   A 1 541 ? 150.679 110.488 93.892  1.00 88.56  ? 566 ALA   A CA  1 
ATOM   4369 C C   . ALA   A 1 541 ? 151.391 110.243 92.569  1.00 93.57  ? 566 ALA   A C   1 
ATOM   4370 O O   . ALA   A 1 541 ? 151.619 109.089 92.186  1.00 96.56  ? 566 ALA   A O   1 
ATOM   4371 C CB  . ALA   A 1 541 ? 149.192 110.760 93.663  1.00 89.61  ? 566 ALA   A CB  1 
ATOM   4372 N N   . GLU   A 1 542 ? 151.749 111.316 91.860  1.00 95.58  ? 567 GLU   A N   1 
ATOM   4373 C CA  . GLU   A 1 542 ? 152.535 111.236 90.636  1.00 97.55  ? 567 GLU   A CA  1 
ATOM   4374 C C   . GLU   A 1 542 ? 153.892 111.918 90.749  1.00 96.34  ? 567 GLU   A C   1 
ATOM   4375 O O   . GLU   A 1 542 ? 154.619 111.974 89.750  1.00 94.11  ? 567 GLU   A O   1 
ATOM   4376 C CB  . GLU   A 1 542 ? 151.760 111.844 89.455  1.00 97.38  ? 567 GLU   A CB  1 
ATOM   4377 C CG  . GLU   A 1 542 ? 151.237 113.266 89.675  1.00 102.34 ? 567 GLU   A CG  1 
ATOM   4378 C CD  . GLU   A 1 542 ? 149.890 113.314 90.379  1.00 105.80 ? 567 GLU   A CD  1 
ATOM   4379 O OE1 . GLU   A 1 542 ? 149.391 112.252 90.807  1.00 104.96 ? 567 GLU   A OE1 1 
ATOM   4380 O OE2 . GLU   A 1 542 ? 149.329 114.423 90.507  1.00 108.56 ? 567 GLU   A OE2 1 
ATOM   4381 N N   . GLN   A 1 543 ? 154.263 112.419 91.930  1.00 95.59  ? 568 GLN   A N   1 
ATOM   4382 C CA  . GLN   A 1 543 ? 155.547 113.087 92.141  1.00 95.00  ? 568 GLN   A CA  1 
ATOM   4383 C C   . GLN   A 1 543 ? 155.715 114.269 91.186  1.00 97.57  ? 568 GLN   A C   1 
ATOM   4384 O O   . GLN   A 1 543 ? 156.711 114.379 90.468  1.00 98.72  ? 568 GLN   A O   1 
ATOM   4385 C CB  . GLN   A 1 543 ? 156.708 112.099 91.998  1.00 94.45  ? 568 GLN   A CB  1 
ATOM   4386 C CG  . GLN   A 1 543 ? 156.699 110.966 93.012  1.00 96.47  ? 568 GLN   A CG  1 
ATOM   4387 C CD  . GLN   A 1 543 ? 156.984 111.439 94.425  1.00 99.67  ? 568 GLN   A CD  1 
ATOM   4388 O OE1 . GLN   A 1 543 ? 157.363 112.590 94.642  1.00 96.40  ? 568 GLN   A OE1 1 
ATOM   4389 N NE2 . GLN   A 1 543 ? 156.802 110.549 95.395  1.00 97.00  ? 568 GLN   A NE2 1 
ATOM   4390 N N   . LYS   A 1 544 ? 154.721 115.156 91.182  1.00 97.86  ? 569 LYS   A N   1 
ATOM   4391 C CA  . LYS   A 1 544 ? 154.693 116.320 90.303  1.00 96.71  ? 569 LYS   A CA  1 
ATOM   4392 C C   . LYS   A 1 544 ? 154.563 117.577 91.148  1.00 95.31  ? 569 LYS   A C   1 
ATOM   4393 O O   . LYS   A 1 544 ? 153.638 117.684 91.958  1.00 101.04 ? 569 LYS   A O   1 
ATOM   4394 C CB  . LYS   A 1 544 ? 153.531 116.225 89.310  1.00 99.14  ? 569 LYS   A CB  1 
ATOM   4395 C CG  . LYS   A 1 544 ? 153.537 117.296 88.224  1.00 102.62 ? 569 LYS   A CG  1 
ATOM   4396 C CD  . LYS   A 1 544 ? 152.293 117.229 87.347  1.00 109.40 ? 569 LYS   A CD  1 
ATOM   4397 C CE  . LYS   A 1 544 ? 152.287 116.001 86.449  1.00 110.67 ? 569 LYS   A CE  1 
ATOM   4398 N NZ  . LYS   A 1 544 ? 151.130 116.003 85.511  1.00 108.16 ? 569 LYS   A NZ  1 
ATOM   4399 N N   . ASN   A 1 545 ? 155.482 118.525 90.956  1.00 87.19  ? 570 ASN   A N   1 
ATOM   4400 C CA  . ASN   A 1 545 ? 155.502 119.766 91.720  1.00 91.32  ? 570 ASN   A CA  1 
ATOM   4401 C C   . ASN   A 1 545 ? 155.440 120.965 90.786  1.00 94.06  ? 570 ASN   A C   1 
ATOM   4402 O O   . ASN   A 1 545 ? 156.137 121.004 89.767  1.00 91.60  ? 570 ASN   A O   1 
ATOM   4403 C CB  . ASN   A 1 545 ? 156.739 119.850 92.619  1.00 89.86  ? 570 ASN   A CB  1 
ATOM   4404 C CG  . ASN   A 1 545 ? 158.018 119.536 91.888  1.00 92.69  ? 570 ASN   A CG  1 
ATOM   4405 O OD1 . ASN   A 1 545 ? 158.025 119.337 90.674  1.00 94.99  ? 570 ASN   A OD1 1 
ATOM   4406 N ND2 . ASN   A 1 545 ? 159.120 119.495 92.628  1.00 92.31  ? 570 ASN   A ND2 1 
ATOM   4407 N N   . GLN   A 1 546 ? 154.596 121.935 91.141  1.00 95.34  ? 571 GLN   A N   1 
ATOM   4408 C CA  . GLN   A 1 546 ? 154.406 123.165 90.383  1.00 89.47  ? 571 GLN   A CA  1 
ATOM   4409 C C   . GLN   A 1 546 ? 154.725 124.365 91.261  1.00 92.20  ? 571 GLN   A C   1 
ATOM   4410 O O   . GLN   A 1 546 ? 154.311 124.421 92.424  1.00 93.85  ? 571 GLN   A O   1 
ATOM   4411 C CB  . GLN   A 1 546 ? 152.970 123.282 89.869  1.00 89.44  ? 571 GLN   A CB  1 
ATOM   4412 C CG  . GLN   A 1 546 ? 152.530 122.144 88.972  1.00 96.41  ? 571 GLN   A CG  1 
ATOM   4413 C CD  . GLN   A 1 546 ? 151.122 122.339 88.447  1.00 102.93 ? 571 GLN   A CD  1 
ATOM   4414 O OE1 . GLN   A 1 546 ? 150.476 123.346 88.737  1.00 99.67  ? 571 GLN   A OE1 1 
ATOM   4415 N NE2 . GLN   A 1 546 ? 150.639 121.376 87.671  1.00 103.62 ? 571 GLN   A NE2 1 
ATOM   4416 N N   . THR   A 1 547 ? 155.444 125.332 90.694  1.00 92.05  ? 572 THR   A N   1 
ATOM   4417 C CA  . THR   A 1 547 ? 155.806 126.558 91.396  1.00 91.63  ? 572 THR   A CA  1 
ATOM   4418 C C   . THR   A 1 547 ? 154.738 127.615 91.141  1.00 91.75  ? 572 THR   A C   1 
ATOM   4419 O O   . THR   A 1 547 ? 154.485 127.979 89.988  1.00 92.24  ? 572 THR   A O   1 
ATOM   4420 C CB  . THR   A 1 547 ? 157.173 127.063 90.938  1.00 93.74  ? 572 THR   A CB  1 
ATOM   4421 O OG1 . THR   A 1 547 ? 157.108 127.449 89.560  1.00 97.25  ? 572 THR   A OG1 1 
ATOM   4422 C CG2 . THR   A 1 547 ? 158.228 125.982 91.105  1.00 90.43  ? 572 THR   A CG2 1 
ATOM   4423 N N   . LEU   A 1 548 ? 154.123 128.109 92.212  1.00 92.02  ? 573 LEU   A N   1 
ATOM   4424 C CA  . LEU   A 1 548 ? 153.030 129.067 92.123  1.00 91.47  ? 573 LEU   A CA  1 
ATOM   4425 C C   . LEU   A 1 548 ? 153.547 130.478 92.365  1.00 97.86  ? 573 LEU   A C   1 
ATOM   4426 O O   . LEU   A 1 548 ? 154.317 130.717 93.300  1.00 97.26  ? 573 LEU   A O   1 
ATOM   4427 C CB  . LEU   A 1 548 ? 151.932 128.734 93.137  1.00 87.33  ? 573 LEU   A CB  1 
ATOM   4428 C CG  . LEU   A 1 548 ? 150.942 127.623 92.772  1.00 84.42  ? 573 LEU   A CG  1 
ATOM   4429 C CD1 . LEU   A 1 548 ? 151.639 126.289 92.569  1.00 88.74  ? 573 LEU   A CD1 1 
ATOM   4430 C CD2 . LEU   A 1 548 ? 149.881 127.502 93.843  1.00 79.32  ? 573 LEU   A CD2 1 
ATOM   4431 N N   . ARG   A 1 549 ? 153.116 131.408 91.517  1.00 101.90 ? 574 ARG   A N   1 
ATOM   4432 C CA  . ARG   A 1 549 ? 153.447 132.819 91.626  1.00 99.71  ? 574 ARG   A CA  1 
ATOM   4433 C C   . ARG   A 1 549 ? 152.266 133.557 92.259  1.00 100.14 ? 574 ARG   A C   1 
ATOM   4434 O O   . ARG   A 1 549 ? 151.263 132.947 92.645  1.00 104.54 ? 574 ARG   A O   1 
ATOM   4435 C CB  . ARG   A 1 549 ? 153.823 133.367 90.245  1.00 100.72 ? 574 ARG   A CB  1 
ATOM   4436 C CG  . ARG   A 1 549 ? 155.302 133.230 89.899  1.00 108.41 ? 574 ARG   A CG  1 
ATOM   4437 C CD  . ARG   A 1 549 ? 155.743 131.775 89.798  1.00 111.17 ? 574 ARG   A CD  1 
ATOM   4438 N NE  . ARG   A 1 549 ? 157.146 131.653 89.413  1.00 115.04 ? 574 ARG   A NE  1 
ATOM   4439 C CZ  . ARG   A 1 549 ? 157.607 131.733 88.170  1.00 119.28 ? 574 ARG   A CZ  1 
ATOM   4440 N NH1 . ARG   A 1 549 ? 156.804 131.953 87.139  1.00 119.12 ? 574 ARG   A NH1 1 
ATOM   4441 N NH2 . ARG   A 1 549 ? 158.912 131.592 87.955  1.00 118.30 ? 574 ARG   A NH2 1 
ATOM   4442 N N   . GLU   A 1 550 ? 152.381 134.878 92.381  1.00 93.74  ? 575 GLU   A N   1 
ATOM   4443 C CA  . GLU   A 1 550 ? 151.348 135.657 93.050  1.00 91.52  ? 575 GLU   A CA  1 
ATOM   4444 C C   . GLU   A 1 550 ? 150.035 135.596 92.280  1.00 95.27  ? 575 GLU   A C   1 
ATOM   4445 O O   . GLU   A 1 550 ? 150.011 135.667 91.048  1.00 97.88  ? 575 GLU   A O   1 
ATOM   4446 C CB  . GLU   A 1 550 ? 151.793 137.110 93.199  1.00 94.16  ? 575 GLU   A CB  1 
ATOM   4447 C CG  . GLU   A 1 550 ? 152.967 137.304 94.137  1.00 99.06  ? 575 GLU   A CG  1 
ATOM   4448 C CD  . GLU   A 1 550 ? 153.345 138.762 94.299  1.00 109.97 ? 575 GLU   A CD  1 
ATOM   4449 O OE1 . GLU   A 1 550 ? 152.680 139.622 93.684  1.00 108.77 ? 575 GLU   A OE1 1 
ATOM   4450 O OE2 . GLU   A 1 550 ? 154.308 139.050 95.041  1.00 114.06 ? 575 GLU   A OE2 1 
ATOM   4451 N N   . GLY   A 1 551 ? 148.939 135.466 93.020  1.00 90.35  ? 576 GLY   A N   1 
ATOM   4452 C CA  . GLY   A 1 551 ? 147.621 135.455 92.408  1.00 89.11  ? 576 GLY   A CA  1 
ATOM   4453 C C   . GLY   A 1 551 ? 147.376 134.273 91.499  1.00 89.12  ? 576 GLY   A C   1 
ATOM   4454 O O   . GLY   A 1 551 ? 146.814 134.440 90.409  1.00 93.36  ? 576 GLY   A O   1 
ATOM   4455 N N   . GLU   A 1 552 ? 147.790 133.079 91.918  1.00 85.29  ? 577 GLU   A N   1 
ATOM   4456 C CA  . GLU   A 1 552 ? 147.555 131.845 91.182  1.00 85.92  ? 577 GLU   A CA  1 
ATOM   4457 C C   . GLU   A 1 552 ? 146.820 130.860 92.076  1.00 83.32  ? 577 GLU   A C   1 
ATOM   4458 O O   . GLU   A 1 552 ? 147.057 130.810 93.286  1.00 88.20  ? 577 GLU   A O   1 
ATOM   4459 C CB  . GLU   A 1 552 ? 148.866 131.232 90.685  1.00 94.34  ? 577 GLU   A CB  1 
ATOM   4460 C CG  . GLU   A 1 552 ? 149.541 132.042 89.591  1.00 102.72 ? 577 GLU   A CG  1 
ATOM   4461 C CD  . GLU   A 1 552 ? 150.733 131.331 88.982  1.00 111.22 ? 577 GLU   A CD  1 
ATOM   4462 O OE1 . GLU   A 1 552 ? 151.066 130.220 89.447  1.00 111.40 ? 577 GLU   A OE1 1 
ATOM   4463 O OE2 . GLU   A 1 552 ? 151.337 131.882 88.038  1.00 114.53 ? 577 GLU   A OE2 1 
ATOM   4464 N N   . LYS   A 1 553 ? 145.929 130.078 91.468  1.00 79.40  ? 578 LYS   A N   1 
ATOM   4465 C CA  . LYS   A 1 553 ? 145.033 129.178 92.178  1.00 78.62  ? 578 LYS   A CA  1 
ATOM   4466 C C   . LYS   A 1 553 ? 145.156 127.779 91.597  1.00 78.65  ? 578 LYS   A C   1 
ATOM   4467 O O   . LYS   A 1 553 ? 145.284 127.616 90.381  1.00 81.10  ? 578 LYS   A O   1 
ATOM   4468 C CB  . LYS   A 1 553 ? 143.585 129.669 92.077  1.00 80.62  ? 578 LYS   A CB  1 
ATOM   4469 C CG  . LYS   A 1 553 ? 142.599 128.927 92.960  1.00 81.32  ? 578 LYS   A CG  1 
ATOM   4470 C CD  . LYS   A 1 553 ? 141.255 129.642 93.032  1.00 87.80  ? 578 LYS   A CD  1 
ATOM   4471 C CE  . LYS   A 1 553 ? 140.537 129.665 91.689  1.00 91.97  ? 578 LYS   A CE  1 
ATOM   4472 N NZ  . LYS   A 1 553 ? 139.169 130.246 91.797  1.00 93.59  ? 578 LYS   A NZ  1 
ATOM   4473 N N   . MET   A 1 554 ? 145.120 126.773 92.471  1.00 81.41  ? 579 MET   A N   1 
ATOM   4474 C CA  . MET   A 1 554 ? 145.245 125.377 92.076  1.00 77.77  ? 579 MET   A CA  1 
ATOM   4475 C C   . MET   A 1 554 ? 144.192 124.547 92.793  1.00 78.17  ? 579 MET   A C   1 
ATOM   4476 O O   . MET   A 1 554 ? 143.824 124.833 93.934  1.00 84.79  ? 579 MET   A O   1 
ATOM   4477 C CB  . MET   A 1 554 ? 146.647 124.838 92.385  1.00 82.53  ? 579 MET   A CB  1 
ATOM   4478 C CG  . MET   A 1 554 ? 146.870 123.378 92.027  1.00 84.99  ? 579 MET   A CG  1 
ATOM   4479 S SD  . MET   A 1 554 ? 148.603 122.908 92.196  1.00 111.41 ? 579 MET   A SD  1 
ATOM   4480 C CE  . MET   A 1 554 ? 148.533 121.170 91.780  1.00 92.22  ? 579 MET   A CE  1 
ATOM   4481 N N   . GLN   A 1 555 ? 143.713 123.509 92.104  1.00 73.21  ? 580 GLN   A N   1 
ATOM   4482 C CA  . GLN   A 1 555 ? 142.677 122.620 92.618  1.00 76.84  ? 580 GLN   A CA  1 
ATOM   4483 C C   . GLN   A 1 555 ? 143.344 121.340 93.110  1.00 81.86  ? 580 GLN   A C   1 
ATOM   4484 O O   . GLN   A 1 555 ? 143.798 120.520 92.305  1.00 85.39  ? 580 GLN   A O   1 
ATOM   4485 C CB  . GLN   A 1 555 ? 141.639 122.322 91.541  1.00 78.58  ? 580 GLN   A CB  1 
ATOM   4486 C CG  . GLN   A 1 555 ? 140.298 121.860 92.075  1.00 75.88  ? 580 GLN   A CG  1 
ATOM   4487 C CD  . GLN   A 1 555 ? 139.489 122.991 92.671  1.00 76.26  ? 580 GLN   A CD  1 
ATOM   4488 O OE1 . GLN   A 1 555 ? 139.986 124.102 92.842  1.00 79.62  ? 580 GLN   A OE1 1 
ATOM   4489 N NE2 . GLN   A 1 555 ? 138.230 122.716 92.983  1.00 76.15  ? 580 GLN   A NE2 1 
ATOM   4490 N N   . LEU   A 1 556 ? 143.400 121.171 94.426  1.00 79.90  ? 581 LEU   A N   1 
ATOM   4491 C CA  . LEU   A 1 556 ? 144.125 120.059 95.012  1.00 77.15  ? 581 LEU   A CA  1 
ATOM   4492 C C   . LEU   A 1 556 ? 143.328 118.758 94.886  1.00 79.66  ? 581 LEU   A C   1 
ATOM   4493 O O   . LEU   A 1 556 ? 142.097 118.787 94.806  1.00 81.10  ? 581 LEU   A O   1 
ATOM   4494 C CB  . LEU   A 1 556 ? 144.414 120.333 96.482  1.00 72.94  ? 581 LEU   A CB  1 
ATOM   4495 C CG  . LEU   A 1 556 ? 145.290 121.549 96.774  1.00 78.72  ? 581 LEU   A CG  1 
ATOM   4496 C CD1 . LEU   A 1 556 ? 145.217 121.899 98.248  1.00 82.91  ? 581 LEU   A CD1 1 
ATOM   4497 C CD2 . LEU   A 1 556 ? 146.727 121.295 96.352  1.00 79.51  ? 581 LEU   A CD2 1 
ATOM   4498 N N   . PRO   A 1 557 ? 143.997 117.601 94.861  1.00 78.06  ? 582 PRO   A N   1 
ATOM   4499 C CA  . PRO   A 1 557 ? 143.256 116.337 94.937  1.00 72.32  ? 582 PRO   A CA  1 
ATOM   4500 C C   . PRO   A 1 557 ? 142.592 116.156 96.291  1.00 73.69  ? 582 PRO   A C   1 
ATOM   4501 O O   . PRO   A 1 557 ? 143.046 116.687 97.307  1.00 80.37  ? 582 PRO   A O   1 
ATOM   4502 C CB  . PRO   A 1 557 ? 144.334 115.272 94.710  1.00 76.66  ? 582 PRO   A CB  1 
ATOM   4503 C CG  . PRO   A 1 557 ? 145.455 115.974 94.077  1.00 82.35  ? 582 PRO   A CG  1 
ATOM   4504 C CD  . PRO   A 1 557 ? 145.429 117.361 94.610  1.00 82.91  ? 582 PRO   A CD  1 
ATOM   4505 N N   . ALA   A 1 558 ? 141.502 115.394 96.290  1.00 71.59  ? 583 ALA   A N   1 
ATOM   4506 C CA  . ALA   A 1 558 ? 140.768 115.039 97.499  1.00 71.64  ? 583 ALA   A CA  1 
ATOM   4507 C C   . ALA   A 1 558 ? 141.023 113.572 97.809  1.00 74.07  ? 583 ALA   A C   1 
ATOM   4508 O O   . ALA   A 1 558 ? 140.763 112.705 96.969  1.00 78.97  ? 583 ALA   A O   1 
ATOM   4509 C CB  . ALA   A 1 558 ? 139.272 115.300 97.329  1.00 74.98  ? 583 ALA   A CB  1 
ATOM   4510 N N   . GLY   A 1 559 ? 141.528 113.299 99.008  1.00 78.05  ? 584 GLY   A N   1 
ATOM   4511 C CA  . GLY   A 1 559 ? 141.832 111.948 99.431  1.00 76.29  ? 584 GLY   A CA  1 
ATOM   4512 C C   . GLY   A 1 559 ? 143.262 111.499 99.227  1.00 74.07  ? 584 GLY   A C   1 
ATOM   4513 O O   . GLY   A 1 559 ? 143.532 110.300 99.351  1.00 73.05  ? 584 GLY   A O   1 
ATOM   4514 N N   . GLU   A 1 560 ? 144.181 112.412 98.917  1.00 73.42  ? 585 GLU   A N   1 
ATOM   4515 C CA  . GLU   A 1 560 ? 145.587 112.099 98.689  1.00 70.55  ? 585 GLU   A CA  1 
ATOM   4516 C C   . GLU   A 1 560 ? 146.451 112.992 99.573  1.00 71.91  ? 585 GLU   A C   1 
ATOM   4517 O O   . GLU   A 1 560 ? 145.949 113.815 100.345 1.00 74.28  ? 585 GLU   A O   1 
ATOM   4518 C CB  . GLU   A 1 560 ? 145.958 112.275 97.212  1.00 74.04  ? 585 GLU   A CB  1 
ATOM   4519 C CG  . GLU   A 1 560 ? 145.180 111.385 96.264  1.00 77.93  ? 585 GLU   A CG  1 
ATOM   4520 C CD  . GLU   A 1 560 ? 145.620 111.552 94.824  1.00 85.21  ? 585 GLU   A CD  1 
ATOM   4521 O OE1 . GLU   A 1 560 ? 146.469 112.427 94.559  1.00 82.20  ? 585 GLU   A OE1 1 
ATOM   4522 O OE2 . GLU   A 1 560 ? 145.116 110.808 93.956  1.00 90.94  ? 585 GLU   A OE2 1 
ATOM   4523 N N   . TYR   A 1 561 ? 147.765 112.819 99.452  1.00 68.91  ? 586 TYR   A N   1 
ATOM   4524 C CA  . TYR   A 1 561 ? 148.751 113.607 100.176 1.00 67.25  ? 586 TYR   A CA  1 
ATOM   4525 C C   . TYR   A 1 561 ? 149.313 114.684 99.262  1.00 68.12  ? 586 TYR   A C   1 
ATOM   4526 O O   . TYR   A 1 561 ? 149.558 114.435 98.078  1.00 74.09  ? 586 TYR   A O   1 
ATOM   4527 C CB  . TYR   A 1 561 ? 149.905 112.734 100.671 1.00 72.35  ? 586 TYR   A CB  1 
ATOM   4528 C CG  . TYR   A 1 561 ? 149.562 111.756 101.768 1.00 74.28  ? 586 TYR   A CG  1 
ATOM   4529 C CD1 . TYR   A 1 561 ? 148.888 110.576 101.489 1.00 76.32  ? 586 TYR   A CD1 1 
ATOM   4530 C CD2 . TYR   A 1 561 ? 149.942 111.996 103.077 1.00 68.52  ? 586 TYR   A CD2 1 
ATOM   4531 C CE1 . TYR   A 1 561 ? 148.586 109.678 102.488 1.00 73.86  ? 586 TYR   A CE1 1 
ATOM   4532 C CE2 . TYR   A 1 561 ? 149.645 111.104 104.079 1.00 69.64  ? 586 TYR   A CE2 1 
ATOM   4533 C CZ  . TYR   A 1 561 ? 148.969 109.946 103.780 1.00 77.15  ? 586 TYR   A CZ  1 
ATOM   4534 O OH  . TYR   A 1 561 ? 148.671 109.054 104.784 1.00 93.62  ? 586 TYR   A OH  1 
ATOM   4535 N N   . HIS   A 1 562 ? 149.511 115.881 99.810  1.00 69.59  ? 587 HIS   A N   1 
ATOM   4536 C CA  . HIS   A 1 562 ? 150.222 116.928 99.091  1.00 68.22  ? 587 HIS   A CA  1 
ATOM   4537 C C   . HIS   A 1 562 ? 151.134 117.665 100.059 1.00 73.46  ? 587 HIS   A C   1 
ATOM   4538 O O   . HIS   A 1 562 ? 151.013 117.540 101.280 1.00 80.19  ? 587 HIS   A O   1 
ATOM   4539 C CB  . HIS   A 1 562 ? 149.264 117.899 98.387  1.00 66.63  ? 587 HIS   A CB  1 
ATOM   4540 C CG  . HIS   A 1 562 ? 148.536 118.822 99.310  1.00 67.97  ? 587 HIS   A CG  1 
ATOM   4541 N ND1 . HIS   A 1 562 ? 147.317 118.506 99.866  1.00 73.86  ? 587 HIS   A ND1 1 
ATOM   4542 C CD2 . HIS   A 1 562 ? 148.841 120.063 99.753  1.00 69.34  ? 587 HIS   A CD2 1 
ATOM   4543 C CE1 . HIS   A 1 562 ? 146.908 119.508 100.623 1.00 75.95  ? 587 HIS   A CE1 1 
ATOM   4544 N NE2 . HIS   A 1 562 ? 147.816 120.465 100.573 1.00 70.01  ? 587 HIS   A NE2 1 
ATOM   4545 N N   . LYS   A 1 563 ? 152.086 118.397 99.488  1.00 72.50  ? 588 LYS   A N   1 
ATOM   4546 C CA  . LYS   A 1 563 ? 153.061 119.162 100.248 1.00 72.31  ? 588 LYS   A CA  1 
ATOM   4547 C C   . LYS   A 1 563 ? 153.164 120.562 99.667  1.00 73.68  ? 588 LYS   A C   1 
ATOM   4548 O O   . LYS   A 1 563 ? 152.986 120.760 98.464  1.00 80.28  ? 588 LYS   A O   1 
ATOM   4549 C CB  . LYS   A 1 563 ? 154.437 118.490 100.229 1.00 75.45  ? 588 LYS   A CB  1 
ATOM   4550 C CG  . LYS   A 1 563 ? 154.478 117.145 100.928 1.00 77.35  ? 588 LYS   A CG  1 
ATOM   4551 C CD  . LYS   A 1 563 ? 155.880 116.562 100.929 1.00 78.87  ? 588 LYS   A CD  1 
ATOM   4552 C CE  . LYS   A 1 563 ? 155.942 115.268 101.719 1.00 80.83  ? 588 LYS   A CE  1 
ATOM   4553 N NZ  . LYS   A 1 563 ? 157.306 114.676 101.716 1.00 80.79  ? 588 LYS   A NZ  1 
ATOM   4554 N N   . VAL   A 1 564 ? 153.425 121.535 100.535 1.00 72.02  ? 589 VAL   A N   1 
ATOM   4555 C CA  . VAL   A 1 564 ? 153.723 122.904 100.122 1.00 72.23  ? 589 VAL   A CA  1 
ATOM   4556 C C   . VAL   A 1 564 ? 155.076 123.285 100.708 1.00 74.03  ? 589 VAL   A C   1 
ATOM   4557 O O   . VAL   A 1 564 ? 155.283 123.190 101.926 1.00 81.55  ? 589 VAL   A O   1 
ATOM   4558 C CB  . VAL   A 1 564 ? 152.623 123.896 100.541 1.00 72.33  ? 589 VAL   A CB  1 
ATOM   4559 C CG1 . VAL   A 1 564 ? 151.323 123.577 99.819  1.00 76.59  ? 589 VAL   A CG1 1 
ATOM   4560 C CG2 . VAL   A 1 564 ? 152.403 123.909 102.045 1.00 75.99  ? 589 VAL   A CG2 1 
ATOM   4561 N N   . TYR   A 1 565 ? 156.002 123.676 99.833  1.00 68.20  ? 590 TYR   A N   1 
ATOM   4562 C CA  . TYR   A 1 565 ? 157.334 124.123 100.210 1.00 67.47  ? 590 TYR   A CA  1 
ATOM   4563 C C   . TYR   A 1 565 ? 157.432 125.626 100.004 1.00 75.94  ? 590 TYR   A C   1 
ATOM   4564 O O   . TYR   A 1 565 ? 156.911 126.158 99.018  1.00 84.96  ? 590 TYR   A O   1 
ATOM   4565 C CB  . TYR   A 1 565 ? 158.424 123.448 99.372  1.00 72.45  ? 590 TYR   A CB  1 
ATOM   4566 C CG  . TYR   A 1 565 ? 158.412 121.940 99.353  1.00 72.68  ? 590 TYR   A CG  1 
ATOM   4567 C CD1 . TYR   A 1 565 ? 157.528 121.242 98.548  1.00 79.24  ? 590 TYR   A CD1 1 
ATOM   4568 C CD2 . TYR   A 1 565 ? 159.315 121.213 100.109 1.00 74.81  ? 590 TYR   A CD2 1 
ATOM   4569 C CE1 . TYR   A 1 565 ? 157.525 119.867 98.518  1.00 82.49  ? 590 TYR   A CE1 1 
ATOM   4570 C CE2 . TYR   A 1 565 ? 159.321 119.838 100.083 1.00 75.22  ? 590 TYR   A CE2 1 
ATOM   4571 C CZ  . TYR   A 1 565 ? 158.426 119.170 99.285  1.00 78.39  ? 590 TYR   A CZ  1 
ATOM   4572 O OH  . TYR   A 1 565 ? 158.426 117.798 99.257  1.00 84.05  ? 590 TYR   A OH  1 
ATOM   4573 N N   . THR   A 1 566 ? 158.115 126.300 100.927 1.00 74.03  ? 591 THR   A N   1 
ATOM   4574 C CA  . THR   A 1 566 ? 158.421 127.719 100.808 1.00 71.35  ? 591 THR   A CA  1 
ATOM   4575 C C   . THR   A 1 566 ? 159.828 127.859 100.245 1.00 76.15  ? 591 THR   A C   1 
ATOM   4576 O O   . THR   A 1 566 ? 160.781 127.308 100.806 1.00 79.06  ? 591 THR   A O   1 
ATOM   4577 C CB  . THR   A 1 566 ? 158.310 128.419 102.161 1.00 70.56  ? 591 THR   A CB  1 
ATOM   4578 O OG1 . THR   A 1 566 ? 157.000 128.216 102.700 1.00 74.04  ? 591 THR   A OG1 1 
ATOM   4579 C CG2 . THR   A 1 566 ? 158.563 129.909 102.017 1.00 75.11  ? 591 THR   A CG2 1 
ATOM   4580 N N   . THR   A 1 567 ? 159.954 128.591 99.142  1.00 78.94  ? 592 THR   A N   1 
ATOM   4581 C CA  . THR   A 1 567 ? 161.206 128.736 98.405  1.00 81.15  ? 592 THR   A CA  1 
ATOM   4582 C C   . THR   A 1 567 ? 161.455 130.197 98.059  1.00 83.01  ? 592 THR   A C   1 
ATOM   4583 O O   . THR   A 1 567 ? 161.790 130.543 96.924  1.00 85.87  ? 592 THR   A O   1 
ATOM   4584 C CB  . THR   A 1 567 ? 161.192 127.881 97.143  1.00 83.06  ? 592 THR   A CB  1 
ATOM   4585 O OG1 . THR   A 1 567 ? 160.074 128.247 96.326  1.00 85.34  ? 592 THR   A OG1 1 
ATOM   4586 C CG2 . THR   A 1 567 ? 161.096 126.407 97.499  1.00 81.44  ? 592 THR   A CG2 1 
ATOM   4587 N N   . SER   A 1 568 ? 161.284 131.073 99.046  1.00 79.64  ? 593 SER   A N   1 
ATOM   4588 C CA  . SER   A 1 568 ? 161.516 132.502 98.916  1.00 80.18  ? 593 SER   A CA  1 
ATOM   4589 C C   . SER   A 1 568 ? 162.430 132.975 100.038 1.00 82.23  ? 593 SER   A C   1 
ATOM   4590 O O   . SER   A 1 568 ? 162.489 132.335 101.091 1.00 86.67  ? 593 SER   A O   1 
ATOM   4591 C CB  . SER   A 1 568 ? 160.196 133.283 98.971  1.00 86.76  ? 593 SER   A CB  1 
ATOM   4592 O OG  . SER   A 1 568 ? 159.503 133.030 100.180 1.00 87.41  ? 593 SER   A OG  1 
ATOM   4593 N N   . PRO   A 1 569 ? 163.162 134.079 99.849  1.00 79.61  ? 594 PRO   A N   1 
ATOM   4594 C CA  . PRO   A 1 569 ? 163.960 134.610 100.968 1.00 80.31  ? 594 PRO   A CA  1 
ATOM   4595 C C   . PRO   A 1 569 ? 163.134 135.078 102.155 1.00 80.50  ? 594 PRO   A C   1 
ATOM   4596 O O   . PRO   A 1 569 ? 163.693 135.225 103.248 1.00 82.77  ? 594 PRO   A O   1 
ATOM   4597 C CB  . PRO   A 1 569 ? 164.725 135.779 100.333 1.00 82.03  ? 594 PRO   A CB  1 
ATOM   4598 C CG  . PRO   A 1 569 ? 164.769 135.470 98.898  1.00 81.18  ? 594 PRO   A CG  1 
ATOM   4599 C CD  . PRO   A 1 569 ? 163.480 134.783 98.592  1.00 79.90  ? 594 PRO   A CD  1 
ATOM   4600 N N   . SER   A 1 570 ? 161.838 135.317 101.981 1.00 81.23  ? 595 SER   A N   1 
ATOM   4601 C CA  . SER   A 1 570 ? 160.954 135.860 102.998 1.00 80.63  ? 595 SER   A CA  1 
ATOM   4602 C C   . SER   A 1 570 ? 159.792 134.904 103.245 1.00 77.81  ? 595 SER   A C   1 
ATOM   4603 O O   . SER   A 1 570 ? 159.569 133.977 102.458 1.00 81.77  ? 595 SER   A O   1 
ATOM   4604 C CB  . SER   A 1 570 ? 160.419 137.233 102.566 1.00 86.86  ? 595 SER   A CB  1 
ATOM   4605 O OG  . SER   A 1 570 ? 159.685 137.135 101.359 1.00 87.28  ? 595 SER   A OG  1 
ATOM   4606 N N   . PRO   A 1 571 ? 159.042 135.083 104.339 1.00 71.99  ? 596 PRO   A N   1 
ATOM   4607 C CA  . PRO   A 1 571 ? 157.902 134.194 104.595 1.00 72.19  ? 596 PRO   A CA  1 
ATOM   4608 C C   . PRO   A 1 571 ? 156.855 134.272 103.494 1.00 72.69  ? 596 PRO   A C   1 
ATOM   4609 O O   . PRO   A 1 571 ? 156.667 135.311 102.859 1.00 71.62  ? 596 PRO   A O   1 
ATOM   4610 C CB  . PRO   A 1 571 ? 157.344 134.706 105.927 1.00 69.08  ? 596 PRO   A CB  1 
ATOM   4611 C CG  . PRO   A 1 571 ? 158.474 135.383 106.574 1.00 72.45  ? 596 PRO   A CG  1 
ATOM   4612 C CD  . PRO   A 1 571 ? 159.279 135.989 105.477 1.00 74.58  ? 596 PRO   A CD  1 
ATOM   4613 N N   . SER   A 1 572 ? 156.172 133.151 103.276 1.00 72.33  ? 597 SER   A N   1 
ATOM   4614 C CA  . SER   A 1 572 ? 155.170 133.016 102.226 1.00 72.17  ? 597 SER   A CA  1 
ATOM   4615 C C   . SER   A 1 572 ? 153.794 132.847 102.853 1.00 74.07  ? 597 SER   A C   1 
ATOM   4616 O O   . SER   A 1 572 ? 153.616 132.016 103.748 1.00 79.33  ? 597 SER   A O   1 
ATOM   4617 C CB  . SER   A 1 572 ? 155.487 131.823 101.325 1.00 77.15  ? 597 SER   A CB  1 
ATOM   4618 O OG  . SER   A 1 572 ? 155.521 130.616 102.067 1.00 82.90  ? 597 SER   A OG  1 
ATOM   4619 N N   . CYS   A 1 573 ? 152.825 133.625 102.373 1.00 71.03  ? 598 CYS   A N   1 
ATOM   4620 C CA  . CYS   A 1 573 ? 151.460 133.615 102.883 1.00 68.26  ? 598 CYS   A CA  1 
ATOM   4621 C C   . CYS   A 1 573 ? 150.514 133.110 101.802 1.00 73.28  ? 598 CYS   A C   1 
ATOM   4622 O O   . CYS   A 1 573 ? 150.505 133.643 100.686 1.00 82.12  ? 598 CYS   A O   1 
ATOM   4623 C CB  . CYS   A 1 573 ? 151.039 135.011 103.338 1.00 68.37  ? 598 CYS   A CB  1 
ATOM   4624 S SG  . CYS   A 1 573 ? 152.070 135.708 104.640 1.00 94.87  ? 598 CYS   A SG  1 
ATOM   4625 N N   . TYR   A 1 574 ? 149.716 132.094 102.144 1.00 69.78  ? 599 TYR   A N   1 
ATOM   4626 C CA  . TYR   A 1 574 ? 148.742 131.505 101.232 1.00 67.81  ? 599 TYR   A CA  1 
ATOM   4627 C C   . TYR   A 1 574 ? 147.494 131.119 102.022 1.00 69.75  ? 599 TYR   A C   1 
ATOM   4628 O O   . TYR   A 1 574 ? 147.393 131.379 103.226 1.00 75.79  ? 599 TYR   A O   1 
ATOM   4629 C CB  . TYR   A 1 574 ? 149.348 130.310 100.484 1.00 70.89  ? 599 TYR   A CB  1 
ATOM   4630 C CG  . TYR   A 1 574 ? 150.015 129.284 101.364 1.00 73.81  ? 599 TYR   A CG  1 
ATOM   4631 C CD1 . TYR   A 1 574 ? 149.289 128.256 101.938 1.00 72.59  ? 599 TYR   A CD1 1 
ATOM   4632 C CD2 . TYR   A 1 574 ? 151.377 129.335 101.606 1.00 76.94  ? 599 TYR   A CD2 1 
ATOM   4633 C CE1 . TYR   A 1 574 ? 149.899 127.316 102.736 1.00 70.95  ? 599 TYR   A CE1 1 
ATOM   4634 C CE2 . TYR   A 1 574 ? 151.993 128.398 102.402 1.00 73.39  ? 599 TYR   A CE2 1 
ATOM   4635 C CZ  . TYR   A 1 574 ? 151.251 127.391 102.964 1.00 69.81  ? 599 TYR   A CZ  1 
ATOM   4636 O OH  . TYR   A 1 574 ? 151.861 126.455 103.760 1.00 76.17  ? 599 TYR   A OH  1 
ATOM   4637 N N   . MET   A 1 575 ? 146.527 130.508 101.336 1.00 70.67  ? 600 MET   A N   1 
ATOM   4638 C CA  . MET   A 1 575 ? 145.225 130.228 101.925 1.00 70.00  ? 600 MET   A CA  1 
ATOM   4639 C C   . MET   A 1 575 ? 144.629 128.963 101.325 1.00 74.48  ? 600 MET   A C   1 
ATOM   4640 O O   . MET   A 1 575 ? 144.819 128.677 100.140 1.00 77.99  ? 600 MET   A O   1 
ATOM   4641 C CB  . MET   A 1 575 ? 144.263 131.402 101.712 1.00 69.93  ? 600 MET   A CB  1 
ATOM   4642 C CG  . MET   A 1 575 ? 144.035 131.769 100.252 1.00 78.12  ? 600 MET   A CG  1 
ATOM   4643 S SD  . MET   A 1 575 ? 143.039 133.255 100.044 1.00 98.23  ? 600 MET   A SD  1 
ATOM   4644 C CE  . MET   A 1 575 ? 141.412 132.639 100.449 1.00 82.86  ? 600 MET   A CE  1 
ATOM   4645 N N   . TYR   A 1 576 ? 143.909 128.215 102.159 1.00 73.81  ? 601 TYR   A N   1 
ATOM   4646 C CA  . TYR   A 1 576 ? 143.112 127.069 101.745 1.00 66.25  ? 601 TYR   A CA  1 
ATOM   4647 C C   . TYR   A 1 576 ? 141.644 127.467 101.759 1.00 69.00  ? 601 TYR   A C   1 
ATOM   4648 O O   . TYR   A 1 576 ? 141.148 127.961 102.775 1.00 76.51  ? 601 TYR   A O   1 
ATOM   4649 C CB  . TYR   A 1 576 ? 143.316 125.878 102.684 1.00 67.44  ? 601 TYR   A CB  1 
ATOM   4650 C CG  . TYR   A 1 576 ? 144.641 125.171 102.560 1.00 68.07  ? 601 TYR   A CG  1 
ATOM   4651 C CD1 . TYR   A 1 576 ? 144.872 124.264 101.542 1.00 68.17  ? 601 TYR   A CD1 1 
ATOM   4652 C CD2 . TYR   A 1 576 ? 145.652 125.388 103.480 1.00 67.71  ? 601 TYR   A CD2 1 
ATOM   4653 C CE1 . TYR   A 1 576 ? 146.074 123.610 101.432 1.00 65.08  ? 601 TYR   A CE1 1 
ATOM   4654 C CE2 . TYR   A 1 576 ? 146.856 124.737 103.376 1.00 69.03  ? 601 TYR   A CE2 1 
ATOM   4655 C CZ  . TYR   A 1 576 ? 147.061 123.848 102.350 1.00 69.05  ? 601 TYR   A CZ  1 
ATOM   4656 O OH  . TYR   A 1 576 ? 148.265 123.194 102.241 1.00 78.02  ? 601 TYR   A OH  1 
ATOM   4657 N N   . VAL   A 1 577 ? 140.958 127.250 100.639 1.00 65.75  ? 602 VAL   A N   1 
ATOM   4658 C CA  . VAL   A 1 577 ? 139.519 127.470 100.515 1.00 64.89  ? 602 VAL   A CA  1 
ATOM   4659 C C   . VAL   A 1 577 ? 138.883 126.122 100.209 1.00 70.36  ? 602 VAL   A C   1 
ATOM   4660 O O   . VAL   A 1 577 ? 139.237 125.483 99.211  1.00 78.75  ? 602 VAL   A O   1 
ATOM   4661 C CB  . VAL   A 1 577 ? 139.189 128.494 99.417  1.00 66.63  ? 602 VAL   A CB  1 
ATOM   4662 C CG1 . VAL   A 1 577 ? 137.692 128.635 99.253  1.00 71.08  ? 602 VAL   A CG1 1 
ATOM   4663 C CG2 . VAL   A 1 577 ? 139.817 129.842 99.737  1.00 72.24  ? 602 VAL   A CG2 1 
ATOM   4664 N N   . TYR   A 1 578 ? 137.953 125.686 101.062 1.00 66.48  ? 603 TYR   A N   1 
ATOM   4665 C CA  . TYR   A 1 578 ? 137.402 124.340 100.950 1.00 61.20  ? 603 TYR   A CA  1 
ATOM   4666 C C   . TYR   A 1 578 ? 135.932 124.312 101.342 1.00 67.72  ? 603 TYR   A C   1 
ATOM   4667 O O   . TYR   A 1 578 ? 135.440 125.175 102.072 1.00 78.76  ? 603 TYR   A O   1 
ATOM   4668 C CB  . TYR   A 1 578 ? 138.184 123.346 101.814 1.00 61.92  ? 603 TYR   A CB  1 
ATOM   4669 C CG  . TYR   A 1 578 ? 138.152 123.637 103.294 1.00 60.31  ? 603 TYR   A CG  1 
ATOM   4670 C CD1 . TYR   A 1 578 ? 139.065 124.505 103.870 1.00 67.48  ? 603 TYR   A CD1 1 
ATOM   4671 C CD2 . TYR   A 1 578 ? 137.227 123.025 104.120 1.00 64.48  ? 603 TYR   A CD2 1 
ATOM   4672 C CE1 . TYR   A 1 578 ? 139.044 124.765 105.220 1.00 67.73  ? 603 TYR   A CE1 1 
ATOM   4673 C CE2 . TYR   A 1 578 ? 137.200 123.280 105.470 1.00 70.58  ? 603 TYR   A CE2 1 
ATOM   4674 C CZ  . TYR   A 1 578 ? 138.112 124.150 106.015 1.00 71.30  ? 603 TYR   A CZ  1 
ATOM   4675 O OH  . TYR   A 1 578 ? 138.090 124.409 107.365 1.00 76.05  ? 603 TYR   A OH  1 
ATOM   4676 N N   . VAL   A 1 579 ? 135.238 123.289 100.838 1.00 67.80  ? 604 VAL   A N   1 
ATOM   4677 C CA  . VAL   A 1 579 ? 133.843 123.020 101.165 1.00 70.28  ? 604 VAL   A CA  1 
ATOM   4678 C C   . VAL   A 1 579 ? 133.685 121.522 101.384 1.00 70.84  ? 604 VAL   A C   1 
ATOM   4679 O O   . VAL   A 1 579 ? 134.407 120.713 100.795 1.00 77.30  ? 604 VAL   A O   1 
ATOM   4680 C CB  . VAL   A 1 579 ? 132.885 123.516 100.057 1.00 77.21  ? 604 VAL   A CB  1 
ATOM   4681 C CG1 . VAL   A 1 579 ? 133.037 122.680 98.794  1.00 77.57  ? 604 VAL   A CG1 1 
ATOM   4682 C CG2 . VAL   A 1 579 ? 131.442 123.506 100.546 1.00 79.71  ? 604 VAL   A CG2 1 
ATOM   4683 N N   . ASN   A 1 580 ? 132.728 121.153 102.234 1.00 69.58  ? 605 ASN   A N   1 
ATOM   4684 C CA  . ASN   A 1 580 ? 132.476 119.759 102.590 1.00 71.62  ? 605 ASN   A CA  1 
ATOM   4685 C C   . ASN   A 1 580 ? 131.374 119.223 101.684 1.00 79.50  ? 605 ASN   A C   1 
ATOM   4686 O O   . ASN   A 1 580 ? 130.210 119.616 101.811 1.00 87.92  ? 605 ASN   A O   1 
ATOM   4687 C CB  . ASN   A 1 580 ? 132.091 119.630 104.063 1.00 70.16  ? 605 ASN   A CB  1 
ATOM   4688 C CG  . ASN   A 1 580 ? 132.176 118.201 104.568 1.00 80.84  ? 605 ASN   A CG  1 
ATOM   4689 O OD1 . ASN   A 1 580 ? 131.859 117.256 103.847 1.00 86.49  ? 605 ASN   A OD1 1 
ATOM   4690 N ND2 . ASN   A 1 580 ? 132.612 118.036 105.813 1.00 84.90  ? 605 ASN   A ND2 1 
ATOM   4691 N N   . THR   A 1 581 ? 131.745 118.326 100.769 1.00 77.79  ? 606 THR   A N   1 
ATOM   4692 C CA  . THR   A 1 581 ? 130.782 117.802 99.805  1.00 75.87  ? 606 THR   A CA  1 
ATOM   4693 C C   . THR   A 1 581 ? 129.773 116.871 100.466 1.00 79.59  ? 606 THR   A C   1 
ATOM   4694 O O   . THR   A 1 581 ? 128.582 116.899 100.129 1.00 89.46  ? 606 THR   A O   1 
ATOM   4695 C CB  . THR   A 1 581 ? 131.517 117.074 98.682  1.00 75.83  ? 606 THR   A CB  1 
ATOM   4696 O OG1 . THR   A 1 581 ? 132.422 117.979 98.038  1.00 80.04  ? 606 THR   A OG1 1 
ATOM   4697 C CG2 . THR   A 1 581 ? 130.534 116.533 97.657  1.00 78.27  ? 606 THR   A CG2 1 
ATOM   4698 N N   . THR   A 1 582 ? 130.231 116.027 101.393 1.00 77.58  ? 607 THR   A N   1 
ATOM   4699 C CA  . THR   A 1 582 ? 129.339 115.057 102.021 1.00 82.88  ? 607 THR   A CA  1 
ATOM   4700 C C   . THR   A 1 582 ? 128.231 115.749 102.805 1.00 88.07  ? 607 THR   A C   1 
ATOM   4701 O O   . THR   A 1 582 ? 127.062 115.350 102.726 1.00 95.82  ? 607 THR   A O   1 
ATOM   4702 C CB  . THR   A 1 582 ? 130.137 114.130 102.936 1.00 85.19  ? 607 THR   A CB  1 
ATOM   4703 O OG1 . THR   A 1 582 ? 131.130 113.437 102.171 1.00 88.34  ? 607 THR   A OG1 1 
ATOM   4704 C CG2 . THR   A 1 582 ? 129.222 113.118 103.605 1.00 87.97  ? 607 THR   A CG2 1 
ATOM   4705 N N   . GLU   A 1 583 ? 128.577 116.793 103.559 1.00 84.84  ? 608 GLU   A N   1 
ATOM   4706 C CA  . GLU   A 1 583 ? 127.562 117.525 104.307 1.00 84.48  ? 608 GLU   A CA  1 
ATOM   4707 C C   . GLU   A 1 583 ? 126.581 118.208 103.366 1.00 85.72  ? 608 GLU   A C   1 
ATOM   4708 O O   . GLU   A 1 583 ? 125.382 118.270 103.650 1.00 94.93  ? 608 GLU   A O   1 
ATOM   4709 C CB  . GLU   A 1 583 ? 128.220 118.552 105.226 1.00 87.70  ? 608 GLU   A CB  1 
ATOM   4710 C CG  . GLU   A 1 583 ? 127.271 119.176 106.236 1.00 94.61  ? 608 GLU   A CG  1 
ATOM   4711 C CD  . GLU   A 1 583 ? 127.970 120.141 107.172 1.00 104.56 ? 608 GLU   A CD  1 
ATOM   4712 O OE1 . GLU   A 1 583 ? 129.210 120.260 107.089 1.00 100.80 ? 608 GLU   A OE1 1 
ATOM   4713 O OE2 . GLU   A 1 583 ? 127.278 120.783 107.990 1.00 111.40 ? 608 GLU   A OE2 1 
ATOM   4714 N N   . LEU   A 1 584 ? 127.071 118.725 102.240 1.00 81.87  ? 609 LEU   A N   1 
ATOM   4715 C CA  . LEU   A 1 584 ? 126.187 119.382 101.284 1.00 84.16  ? 609 LEU   A CA  1 
ATOM   4716 C C   . LEU   A 1 584 ? 125.192 118.391 100.690 1.00 92.54  ? 609 LEU   A C   1 
ATOM   4717 O O   . LEU   A 1 584 ? 123.992 118.680 100.588 1.00 101.55 ? 609 LEU   A O   1 
ATOM   4718 C CB  . LEU   A 1 584 ? 127.018 120.044 100.185 1.00 83.84  ? 609 LEU   A CB  1 
ATOM   4719 C CG  . LEU   A 1 584 ? 126.303 121.024 99.254  1.00 90.54  ? 609 LEU   A CG  1 
ATOM   4720 C CD1 . LEU   A 1 584 ? 125.839 122.260 100.008 1.00 93.98  ? 609 LEU   A CD1 1 
ATOM   4721 C CD2 . LEU   A 1 584 ? 127.216 121.413 98.103  1.00 89.42  ? 609 LEU   A CD2 1 
ATOM   4722 N N   . ALA   A 1 585 ? 125.674 117.210 100.299 1.00 90.58  ? 610 ALA   A N   1 
ATOM   4723 C CA  . ALA   A 1 585 ? 124.777 116.190 99.763  1.00 90.47  ? 610 ALA   A CA  1 
ATOM   4724 C C   . ALA   A 1 585 ? 123.767 115.737 100.811 1.00 95.11  ? 610 ALA   A C   1 
ATOM   4725 O O   . ALA   A 1 585 ? 122.579 115.559 100.506 1.00 102.42 ? 610 ALA   A O   1 
ATOM   4726 C CB  . ALA   A 1 585 ? 125.585 115.001 99.248  1.00 82.55  ? 610 ALA   A CB  1 
ATOM   4727 N N   . LEU   A 1 586 ? 124.223 115.537 102.050 1.00 90.62  ? 611 LEU   A N   1 
ATOM   4728 C CA  . LEU   A 1 586 ? 123.311 115.145 103.118 1.00 91.00  ? 611 LEU   A CA  1 
ATOM   4729 C C   . LEU   A 1 586 ? 122.253 116.214 103.354 1.00 97.73  ? 611 LEU   A C   1 
ATOM   4730 O O   . LEU   A 1 586 ? 121.081 115.895 103.574 1.00 107.15 ? 611 LEU   A O   1 
ATOM   4731 C CB  . LEU   A 1 586 ? 124.098 114.872 104.399 1.00 92.90  ? 611 LEU   A CB  1 
ATOM   4732 C CG  . LEU   A 1 586 ? 123.317 114.405 105.630 1.00 103.27 ? 611 LEU   A CG  1 
ATOM   4733 C CD1 . LEU   A 1 586 ? 122.602 113.088 105.366 1.00 105.80 ? 611 LEU   A CD1 1 
ATOM   4734 C CD2 . LEU   A 1 586 ? 124.250 114.274 106.822 1.00 102.95 ? 611 LEU   A CD2 1 
ATOM   4735 N N   . GLU   A 1 587 ? 122.648 117.487 103.321 1.00 97.94  ? 612 GLU   A N   1 
ATOM   4736 C CA  . GLU   A 1 587 ? 121.689 118.567 103.520 1.00 101.06 ? 612 GLU   A CA  1 
ATOM   4737 C C   . GLU   A 1 587 ? 120.673 118.616 102.389 1.00 101.64 ? 612 GLU   A C   1 
ATOM   4738 O O   . GLU   A 1 587 ? 119.484 118.854 102.629 1.00 110.32 ? 612 GLU   A O   1 
ATOM   4739 C CB  . GLU   A 1 587 ? 122.424 119.902 103.639 1.00 102.65 ? 612 GLU   A CB  1 
ATOM   4740 C CG  . GLU   A 1 587 ? 121.544 121.061 104.080 1.00 108.79 ? 612 GLU   A CG  1 
ATOM   4741 C CD  . GLU   A 1 587 ? 122.325 122.348 104.259 1.00 116.47 ? 612 GLU   A CD  1 
ATOM   4742 O OE1 . GLU   A 1 587 ? 123.557 122.330 104.053 1.00 117.97 ? 612 GLU   A OE1 1 
ATOM   4743 O OE2 . GLU   A 1 587 ? 121.707 123.377 104.605 1.00 116.14 ? 612 GLU   A OE2 1 
ATOM   4744 N N   . GLN   A 1 588 ? 121.119 118.397 101.150 1.00 97.88  ? 613 GLN   A N   1 
ATOM   4745 C CA  . GLN   A 1 588 ? 120.178 118.369 100.033 1.00 103.12 ? 613 GLN   A CA  1 
ATOM   4746 C C   . GLN   A 1 588 ? 119.177 117.231 100.189 1.00 108.03 ? 613 GLN   A C   1 
ATOM   4747 O O   . GLN   A 1 588 ? 117.968 117.420 99.990  1.00 114.43 ? 613 GLN   A O   1 
ATOM   4748 C CB  . GLN   A 1 588 ? 120.935 118.240 98.712  1.00 104.81 ? 613 GLN   A CB  1 
ATOM   4749 C CG  . GLN   A 1 588 ? 121.715 119.483 98.318  1.00 106.37 ? 613 GLN   A CG  1 
ATOM   4750 C CD  . GLN   A 1 588 ? 122.543 119.275 97.067  1.00 106.36 ? 613 GLN   A CD  1 
ATOM   4751 O OE1 . GLN   A 1 588 ? 122.375 118.285 96.355  1.00 106.30 ? 613 GLN   A OE1 1 
ATOM   4752 N NE2 . GLN   A 1 588 ? 123.448 120.207 96.794  1.00 103.81 ? 613 GLN   A NE2 1 
ATOM   4753 N N   . ASP   A 1 589 ? 119.659 116.043 100.560 1.00 104.99 ? 614 ASP   A N   1 
ATOM   4754 C CA  . ASP   A 1 589 ? 118.755 114.913 100.751 1.00 107.83 ? 614 ASP   A CA  1 
ATOM   4755 C C   . ASP   A 1 589 ? 117.789 115.168 101.903 1.00 111.03 ? 614 ASP   A C   1 
ATOM   4756 O O   . ASP   A 1 589 ? 116.605 114.818 101.824 1.00 118.17 ? 614 ASP   A O   1 
ATOM   4757 C CB  . ASP   A 1 589 ? 119.559 113.639 100.998 1.00 113.86 ? 614 ASP   A CB  1 
ATOM   4758 C CG  . ASP   A 1 589 ? 120.468 113.290 99.836  1.00 118.01 ? 614 ASP   A CG  1 
ATOM   4759 O OD1 . ASP   A 1 589 ? 120.455 114.026 98.828  1.00 116.26 ? 614 ASP   A OD1 1 
ATOM   4760 O OD2 . ASP   A 1 589 ? 121.196 112.279 99.932  1.00 121.62 ? 614 ASP   A OD2 1 
ATOM   4761 N N   . LEU   A 1 590 ? 118.279 115.779 102.982 1.00 109.98 ? 615 LEU   A N   1 
ATOM   4762 C CA  . LEU   A 1 590 ? 117.422 116.078 104.122 1.00 111.53 ? 615 LEU   A CA  1 
ATOM   4763 C C   . LEU   A 1 590 ? 116.346 117.087 103.745 1.00 112.66 ? 615 LEU   A C   1 
ATOM   4764 O O   . LEU   A 1 590 ? 115.187 116.954 104.155 1.00 120.78 ? 615 LEU   A O   1 
ATOM   4765 C CB  . LEU   A 1 590 ? 118.274 116.596 105.281 1.00 112.15 ? 615 LEU   A CB  1 
ATOM   4766 C CG  . LEU   A 1 590 ? 117.732 116.401 106.698 1.00 122.66 ? 615 LEU   A CG  1 
ATOM   4767 C CD1 . LEU   A 1 590 ? 118.886 116.364 107.690 1.00 123.71 ? 615 LEU   A CD1 1 
ATOM   4768 C CD2 . LEU   A 1 590 ? 116.733 117.491 107.075 1.00 124.60 ? 615 LEU   A CD2 1 
ATOM   4769 N N   . ALA   A 1 591 ? 116.711 118.105 102.965 1.00 110.66 ? 616 ALA   A N   1 
ATOM   4770 C CA  . ALA   A 1 591 ? 115.723 119.075 102.505 1.00 114.49 ? 616 ALA   A CA  1 
ATOM   4771 C C   . ALA   A 1 591 ? 114.678 118.412 101.621 1.00 118.91 ? 616 ALA   A C   1 
ATOM   4772 O O   . ALA   A 1 591 ? 113.484 118.713 101.728 1.00 122.66 ? 616 ALA   A O   1 
ATOM   4773 C CB  . ALA   A 1 591 ? 116.416 120.213 101.757 1.00 115.73 ? 616 ALA   A CB  1 
ATOM   4774 N N   . TYR   A 1 592 ? 115.108 117.507 100.738 1.00 121.12 ? 617 TYR   A N   1 
ATOM   4775 C CA  . TYR   A 1 592 ? 114.156 116.777 99.904  1.00 122.67 ? 617 TYR   A CA  1 
ATOM   4776 C C   . TYR   A 1 592 ? 113.194 115.954 100.754 1.00 123.46 ? 617 TYR   A C   1 
ATOM   4777 O O   . TYR   A 1 592 ? 111.981 115.941 100.503 1.00 128.26 ? 617 TYR   A O   1 
ATOM   4778 C CB  . TYR   A 1 592 ? 114.912 115.880 98.925  1.00 125.82 ? 617 TYR   A CB  1 
ATOM   4779 C CG  . TYR   A 1 592 ? 114.038 114.939 98.126  1.00 132.98 ? 617 TYR   A CG  1 
ATOM   4780 C CD1 . TYR   A 1 592 ? 113.373 115.376 96.988  1.00 136.00 ? 617 TYR   A CD1 1 
ATOM   4781 C CD2 . TYR   A 1 592 ? 113.892 113.610 98.500  1.00 131.81 ? 617 TYR   A CD2 1 
ATOM   4782 C CE1 . TYR   A 1 592 ? 112.579 114.517 96.251  1.00 137.87 ? 617 TYR   A CE1 1 
ATOM   4783 C CE2 . TYR   A 1 592 ? 113.100 112.745 97.770  1.00 135.59 ? 617 TYR   A CE2 1 
ATOM   4784 C CZ  . TYR   A 1 592 ? 112.447 113.203 96.646  1.00 138.91 ? 617 TYR   A CZ  1 
ATOM   4785 O OH  . TYR   A 1 592 ? 111.657 112.345 95.916  1.00 136.79 ? 617 TYR   A OH  1 
ATOM   4786 N N   . LEU   A 1 593 ? 113.718 115.260 101.764 1.00 122.93 ? 618 LEU   A N   1 
ATOM   4787 C CA  . LEU   A 1 593 ? 112.863 114.445 102.621 1.00 126.10 ? 618 LEU   A CA  1 
ATOM   4788 C C   . LEU   A 1 593 ? 111.878 115.309 103.399 1.00 126.51 ? 618 LEU   A C   1 
ATOM   4789 O O   . LEU   A 1 593 ? 110.703 114.948 103.548 1.00 131.03 ? 618 LEU   A O   1 
ATOM   4790 C CB  . LEU   A 1 593 ? 113.725 113.618 103.577 1.00 128.68 ? 618 LEU   A CB  1 
ATOM   4791 C CG  . LEU   A 1 593 ? 113.034 112.492 104.353 1.00 134.79 ? 618 LEU   A CG  1 
ATOM   4792 C CD1 . LEU   A 1 593 ? 112.498 111.425 103.402 1.00 135.79 ? 618 LEU   A CD1 1 
ATOM   4793 C CD2 . LEU   A 1 593 ? 113.980 111.872 105.381 1.00 136.28 ? 618 LEU   A CD2 1 
ATOM   4794 N N   . GLN   A 1 594 ? 112.338 116.455 103.907 1.00 126.17 ? 619 GLN   A N   1 
ATOM   4795 C CA  . GLN   A 1 594 ? 111.438 117.364 104.607 1.00 127.13 ? 619 GLN   A CA  1 
ATOM   4796 C C   . GLN   A 1 594 ? 110.361 117.892 103.671 1.00 128.87 ? 619 GLN   A C   1 
ATOM   4797 O O   . GLN   A 1 594 ? 109.205 118.055 104.074 1.00 133.10 ? 619 GLN   A O   1 
ATOM   4798 C CB  . GLN   A 1 594 ? 112.228 118.520 105.222 1.00 128.79 ? 619 GLN   A CB  1 
ATOM   4799 C CG  . GLN   A 1 594 ? 111.388 119.476 106.060 1.00 129.38 ? 619 GLN   A CG  1 
ATOM   4800 C CD  . GLN   A 1 594 ? 112.221 120.537 106.747 1.00 130.98 ? 619 GLN   A CD  1 
ATOM   4801 O OE1 . GLN   A 1 594 ? 113.451 120.476 106.746 1.00 131.15 ? 619 GLN   A OE1 1 
ATOM   4802 N NE2 . GLN   A 1 594 ? 111.554 121.522 107.338 1.00 130.87 ? 619 GLN   A NE2 1 
ATOM   4803 N N   . GLU   A 1 595 ? 110.726 118.185 102.422 1.00 129.24 ? 620 GLU   A N   1 
ATOM   4804 C CA  . GLU   A 1 595 ? 109.737 118.646 101.456 1.00 135.26 ? 620 GLU   A CA  1 
ATOM   4805 C C   . GLU   A 1 595 ? 108.687 117.574 101.199 1.00 137.93 ? 620 GLU   A C   1 
ATOM   4806 O O   . GLU   A 1 595 ? 107.493 117.875 101.101 1.00 142.74 ? 620 GLU   A O   1 
ATOM   4807 C CB  . GLU   A 1 595 ? 110.430 119.047 100.153 1.00 137.44 ? 620 GLU   A CB  1 
ATOM   4808 C CG  . GLU   A 1 595 ? 109.501 119.640 99.101  1.00 142.98 ? 620 GLU   A CG  1 
ATOM   4809 C CD  . GLU   A 1 595 ? 110.252 120.166 97.893  1.00 144.16 ? 620 GLU   A CD  1 
ATOM   4810 O OE1 . GLU   A 1 595 ? 111.494 120.045 97.865  1.00 140.53 ? 620 GLU   A OE1 1 
ATOM   4811 O OE2 . GLU   A 1 595 ? 109.599 120.701 96.973  1.00 144.03 ? 620 GLU   A OE2 1 
ATOM   4812 N N   . LEU   A 1 596 ? 109.116 116.316 101.087 1.00 136.79 ? 621 LEU   A N   1 
ATOM   4813 C CA  . LEU   A 1 596 ? 108.157 115.227 100.915 1.00 137.01 ? 621 LEU   A CA  1 
ATOM   4814 C C   . LEU   A 1 596 ? 107.238 115.107 102.126 1.00 135.24 ? 621 LEU   A C   1 
ATOM   4815 O O   . LEU   A 1 596 ? 106.026 114.901 101.978 1.00 140.11 ? 621 LEU   A O   1 
ATOM   4816 C CB  . LEU   A 1 596 ? 108.889 113.907 100.664 1.00 139.85 ? 621 LEU   A CB  1 
ATOM   4817 C CG  . LEU   A 1 596 ? 109.070 113.512 99.194  1.00 141.75 ? 621 LEU   A CG  1 
ATOM   4818 C CD1 . LEU   A 1 596 ? 109.905 114.528 98.421  1.00 139.83 ? 621 LEU   A CD1 1 
ATOM   4819 C CD2 . LEU   A 1 596 ? 109.692 112.127 99.097  1.00 139.43 ? 621 LEU   A CD2 1 
ATOM   4820 N N   . LYS   A 1 597 ? 107.798 115.227 103.331 1.00 134.04 ? 622 LYS   A N   1 
ATOM   4821 C CA  . LYS   A 1 597 ? 106.976 115.173 104.537 1.00 137.11 ? 622 LYS   A CA  1 
ATOM   4822 C C   . LYS   A 1 597 ? 105.955 116.304 104.558 1.00 140.75 ? 622 LYS   A C   1 
ATOM   4823 O O   . LYS   A 1 597 ? 104.789 116.091 104.907 1.00 143.38 ? 622 LYS   A O   1 
ATOM   4824 C CB  . LYS   A 1 597 ? 107.863 115.233 105.781 1.00 140.54 ? 622 LYS   A CB  1 
ATOM   4825 C CG  . LYS   A 1 597 ? 107.096 115.172 107.105 1.00 141.88 ? 622 LYS   A CG  1 
ATOM   4826 C CD  . LYS   A 1 597 ? 108.022 115.041 108.312 1.00 141.00 ? 622 LYS   A CD  1 
ATOM   4827 C CE  . LYS   A 1 597 ? 108.409 116.396 108.895 1.00 139.93 ? 622 LYS   A CE  1 
ATOM   4828 N NZ  . LYS   A 1 597 ? 109.193 117.240 107.952 1.00 139.12 ? 622 LYS   A NZ  1 
ATOM   4829 N N   . GLU   A 1 598 ? 106.377 117.514 104.191 1.00 143.09 ? 623 GLU   A N   1 
ATOM   4830 C CA  . GLU   A 1 598 ? 105.456 118.646 104.168 1.00 145.78 ? 623 GLU   A CA  1 
ATOM   4831 C C   . GLU   A 1 598 ? 104.362 118.443 103.128 1.00 148.27 ? 623 GLU   A C   1 
ATOM   4832 O O   . GLU   A 1 598 ? 103.193 118.764 103.375 1.00 149.34 ? 623 GLU   A O   1 
ATOM   4833 C CB  . GLU   A 1 598 ? 106.222 119.940 103.896 1.00 146.12 ? 623 GLU   A CB  1 
ATOM   4834 C CG  . GLU   A 1 598 ? 107.099 120.394 105.052 1.00 146.45 ? 623 GLU   A CG  1 
ATOM   4835 C CD  . GLU   A 1 598 ? 107.915 121.627 104.717 1.00 145.76 ? 623 GLU   A CD  1 
ATOM   4836 O OE1 . GLU   A 1 598 ? 107.759 122.159 103.598 1.00 143.95 ? 623 GLU   A OE1 1 
ATOM   4837 O OE2 . GLU   A 1 598 ? 108.712 122.065 105.573 1.00 144.15 ? 623 GLU   A OE2 1 
ATOM   4838 N N   . LYS   A 1 599 ? 104.725 117.919 101.956 1.00 150.54 ? 624 LYS   A N   1 
ATOM   4839 C CA  . LYS   A 1 599 ? 103.728 117.638 100.929 1.00 154.49 ? 624 LYS   A CA  1 
ATOM   4840 C C   . LYS   A 1 599 ? 102.708 116.618 101.418 1.00 154.57 ? 624 LYS   A C   1 
ATOM   4841 O O   . LYS   A 1 599 ? 101.506 116.761 101.167 1.00 158.16 ? 624 LYS   A O   1 
ATOM   4842 C CB  . LYS   A 1 599 ? 104.412 117.145 99.654  1.00 154.37 ? 624 LYS   A CB  1 
ATOM   4843 C CG  . LYS   A 1 599 ? 105.111 118.240 98.863  1.00 152.06 ? 624 LYS   A CG  1 
ATOM   4844 C CD  . LYS   A 1 599 ? 105.840 117.673 97.656  1.00 148.00 ? 624 LYS   A CD  1 
ATOM   4845 C CE  . LYS   A 1 599 ? 106.462 118.774 96.813  1.00 147.94 ? 624 LYS   A CE  1 
ATOM   4846 N NZ  . LYS   A 1 599 ? 107.278 118.230 95.693  1.00 145.70 ? 624 LYS   A NZ  1 
ATOM   4847 N N   . VAL   A 1 600 ? 103.171 115.573 102.106 1.00 154.83 ? 625 VAL   A N   1 
ATOM   4848 C CA  . VAL   A 1 600 ? 102.244 114.593 102.665 1.00 156.54 ? 625 VAL   A CA  1 
ATOM   4849 C C   . VAL   A 1 600 ? 101.345 115.247 103.709 1.00 150.79 ? 625 VAL   A C   1 
ATOM   4850 O O   . VAL   A 1 600 ? 100.141 114.972 103.772 1.00 148.85 ? 625 VAL   A O   1 
ATOM   4851 C CB  . VAL   A 1 600 ? 103.018 113.396 103.250 1.00 157.54 ? 625 VAL   A CB  1 
ATOM   4852 C CG1 . VAL   A 1 600 ? 102.090 112.493 104.058 1.00 154.82 ? 625 VAL   A CG1 1 
ATOM   4853 C CG2 . VAL   A 1 600 ? 103.687 112.599 102.137 1.00 155.93 ? 625 VAL   A CG2 1 
ATOM   4854 N N   . GLU   A 1 601 ? 101.914 116.120 104.543 1.00 146.84 ? 626 GLU   A N   1 
ATOM   4855 C CA  . GLU   A 1 601 ? 101.145 116.704 105.638 1.00 147.37 ? 626 GLU   A CA  1 
ATOM   4856 C C   . GLU   A 1 601 ? 100.063 117.650 105.128 1.00 148.74 ? 626 GLU   A C   1 
ATOM   4857 O O   . GLU   A 1 601 ? 98.930  117.623 105.620 1.00 147.97 ? 626 GLU   A O   1 
ATOM   4858 C CB  . GLU   A 1 601 ? 102.079 117.432 106.602 1.00 149.45 ? 626 GLU   A CB  1 
ATOM   4859 C CG  . GLU   A 1 601 ? 102.876 116.504 107.505 1.00 150.52 ? 626 GLU   A CG  1 
ATOM   4860 C CD  . GLU   A 1 601 ? 103.890 117.245 108.355 1.00 150.29 ? 626 GLU   A CD  1 
ATOM   4861 O OE1 . GLU   A 1 601 ? 103.907 118.493 108.310 1.00 149.33 ? 626 GLU   A OE1 1 
ATOM   4862 O OE2 . GLU   A 1 601 ? 104.670 116.579 109.067 1.00 149.62 ? 626 GLU   A OE2 1 
ATOM   4863 N N   . ASN   A 1 602 ? 100.386 118.490 104.145 1.00 152.49 ? 627 ASN   A N   1 
ATOM   4864 C CA  . ASN   A 1 602 ? 99.434  119.490 103.670 1.00 155.17 ? 627 ASN   A CA  1 
ATOM   4865 C C   . ASN   A 1 602 ? 98.351  118.912 102.763 1.00 158.13 ? 627 ASN   A C   1 
ATOM   4866 O O   . ASN   A 1 602 ? 97.470  119.664 102.332 1.00 157.78 ? 627 ASN   A O   1 
ATOM   4867 C CB  . ASN   A 1 602 ? 100.166 120.635 102.948 1.00 151.06 ? 627 ASN   A CB  1 
ATOM   4868 C CG  . ASN   A 1 602 ? 101.012 120.166 101.771 1.00 152.57 ? 627 ASN   A CG  1 
ATOM   4869 O OD1 . ASN   A 1 602 ? 100.627 119.275 101.015 1.00 158.13 ? 627 ASN   A OD1 1 
ATOM   4870 N ND2 . ASN   A 1 602 ? 102.179 120.781 101.612 1.00 149.46 ? 627 ASN   A ND2 1 
ATOM   4871 N N   . GLY   A 1 603 ? 98.395  117.611 102.459 1.00 158.92 ? 628 GLY   A N   1 
ATOM   4872 C CA  . GLY   A 1 603 ? 97.399  116.951 101.645 1.00 158.86 ? 628 GLY   A CA  1 
ATOM   4873 C C   . GLY   A 1 603 ? 97.849  116.622 100.236 1.00 166.30 ? 628 GLY   A C   1 
ATOM   4874 O O   . GLY   A 1 603 ? 97.210  115.795 99.576  1.00 171.03 ? 628 GLY   A O   1 
ATOM   4875 N N   . SER   A 1 604 ? 98.926  117.241 99.760  1.00 169.30 ? 629 SER   A N   1 
ATOM   4876 C CA  . SER   A 1 604 ? 99.470  116.888 98.460  1.00 173.32 ? 629 SER   A CA  1 
ATOM   4877 C C   . SER   A 1 604 ? 100.134 115.513 98.526  1.00 176.14 ? 629 SER   A C   1 
ATOM   4878 O O   . SER   A 1 604 ? 100.270 114.906 99.593  1.00 173.93 ? 629 SER   A O   1 
ATOM   4879 C CB  . SER   A 1 604 ? 100.466 117.947 97.990  1.00 168.69 ? 629 SER   A CB  1 
ATOM   4880 O OG  . SER   A 1 604 ? 101.552 118.062 98.891  1.00 167.87 ? 629 SER   A OG  1 
ATOM   4881 N N   . GLU   A 1 605 ? 100.554 115.022 97.359  1.00 179.31 ? 630 GLU   A N   1 
ATOM   4882 C CA  . GLU   A 1 605 ? 101.142 113.690 97.225  1.00 181.74 ? 630 GLU   A CA  1 
ATOM   4883 C C   . GLU   A 1 605 ? 100.163 112.622 97.718  1.00 183.49 ? 630 GLU   A C   1 
ATOM   4884 O O   . GLU   A 1 605 ? 100.421 111.884 98.672  1.00 178.76 ? 630 GLU   A O   1 
ATOM   4885 C CB  . GLU   A 1 605 ? 102.481 113.608 97.971  1.00 176.83 ? 630 GLU   A CB  1 
ATOM   4886 C CG  . GLU   A 1 605 ? 103.308 112.358 97.673  1.00 177.83 ? 630 GLU   A CG  1 
ATOM   4887 C CD  . GLU   A 1 605 ? 103.832 112.317 96.249  1.00 177.00 ? 630 GLU   A CD  1 
ATOM   4888 O OE1 . GLU   A 1 605 ? 103.731 113.343 95.543  1.00 178.66 ? 630 GLU   A OE1 1 
ATOM   4889 O OE2 . GLU   A 1 605 ? 104.344 111.256 95.835  1.00 170.92 ? 630 GLU   A OE2 1 
ATOM   4890 N N   . THR   A 1 606 ? 99.013  112.561 97.042  1.00 188.07 ? 631 THR   A N   1 
ATOM   4891 C CA  . THR   A 1 606 ? 97.962  111.624 97.423  1.00 188.49 ? 631 THR   A CA  1 
ATOM   4892 C C   . THR   A 1 606 ? 98.390  110.168 97.278  1.00 190.20 ? 631 THR   A C   1 
ATOM   4893 O O   . THR   A 1 606 ? 97.790  109.295 97.915  1.00 188.82 ? 631 THR   A O   1 
ATOM   4894 C CB  . THR   A 1 606 ? 96.708  111.872 96.581  1.00 186.56 ? 631 THR   A CB  1 
ATOM   4895 O OG1 . THR   A 1 606 ? 97.024  111.723 95.191  1.00 186.82 ? 631 THR   A OG1 1 
ATOM   4896 C CG2 . THR   A 1 606 ? 96.160  113.271 96.829  1.00 181.02 ? 631 THR   A CG2 1 
ATOM   4897 N N   . GLY   A 1 607 ? 99.401  109.884 96.459  1.00 190.47 ? 632 GLY   A N   1 
ATOM   4898 C CA  . GLY   A 1 607 ? 99.865  108.532 96.266  1.00 188.75 ? 632 GLY   A CA  1 
ATOM   4899 C C   . GLY   A 1 607 ? 100.427 107.942 97.546  1.00 189.22 ? 632 GLY   A C   1 
ATOM   4900 O O   . GLY   A 1 607 ? 100.816 108.674 98.462  1.00 187.18 ? 632 GLY   A O   1 
ATOM   4901 N N   . PRO   A 1 608 ? 100.467 106.611 97.647  1.00 189.91 ? 633 PRO   A N   1 
ATOM   4902 C CA  . PRO   A 1 608 ? 100.960 105.990 98.883  1.00 186.03 ? 633 PRO   A CA  1 
ATOM   4903 C C   . PRO   A 1 608 ? 102.423 106.325 99.139  1.00 182.65 ? 633 PRO   A C   1 
ATOM   4904 O O   . PRO   A 1 608 ? 103.236 106.401 98.215  1.00 181.30 ? 633 PRO   A O   1 
ATOM   4905 C CB  . PRO   A 1 608 ? 100.760 104.492 98.632  1.00 184.36 ? 633 PRO   A CB  1 
ATOM   4906 C CG  . PRO   A 1 608 ? 100.816 104.352 97.158  1.00 184.68 ? 633 PRO   A CG  1 
ATOM   4907 C CD  . PRO   A 1 608 ? 100.198 105.603 96.604  1.00 186.28 ? 633 PRO   A CD  1 
ATOM   4908 N N   . LEU   A 1 609 ? 102.751 106.525 100.412 1.00 178.91 ? 634 LEU   A N   1 
ATOM   4909 C CA  . LEU   A 1 609 ? 104.118 106.849 100.783 1.00 174.84 ? 634 LEU   A CA  1 
ATOM   4910 C C   . LEU   A 1 609 ? 105.019 105.622 100.608 1.00 172.43 ? 634 LEU   A C   1 
ATOM   4911 O O   . LEU   A 1 609 ? 104.552 104.485 100.714 1.00 171.84 ? 634 LEU   A O   1 
ATOM   4912 C CB  . LEU   A 1 609 ? 104.186 107.345 102.228 1.00 171.83 ? 634 LEU   A CB  1 
ATOM   4913 C CG  . LEU   A 1 609 ? 104.047 106.369 103.409 1.00 170.82 ? 634 LEU   A CG  1 
ATOM   4914 C CD1 . LEU   A 1 609 ? 104.391 107.103 104.693 1.00 169.13 ? 634 LEU   A CD1 1 
ATOM   4915 C CD2 . LEU   A 1 609 ? 102.657 105.746 103.498 1.00 170.69 ? 634 LEU   A CD2 1 
ATOM   4916 N N   . PRO   A 1 610 ? 106.312 105.816 100.341 1.00 170.11 ? 635 PRO   A N   1 
ATOM   4917 C CA  . PRO   A 1 610 ? 107.225 104.677 100.354 1.00 167.99 ? 635 PRO   A CA  1 
ATOM   4918 C C   . PRO   A 1 610 ? 107.334 104.100 101.750 1.00 166.11 ? 635 PRO   A C   1 
ATOM   4919 O O   . PRO   A 1 610 ? 107.076 104.798 102.749 1.00 164.71 ? 635 PRO   A O   1 
ATOM   4920 C CB  . PRO   A 1 610 ? 108.557 105.283 99.889  1.00 165.39 ? 635 PRO   A CB  1 
ATOM   4921 C CG  . PRO   A 1 610 ? 108.198 106.512 99.173  1.00 165.69 ? 635 PRO   A CG  1 
ATOM   4922 C CD  . PRO   A 1 610 ? 106.988 107.037 99.862  1.00 167.73 ? 635 PRO   A CD  1 
ATOM   4923 N N   . PRO   A 1 611 ? 107.694 102.816 101.875 1.00 165.91 ? 636 PRO   A N   1 
ATOM   4924 C CA  . PRO   A 1 611 ? 107.860 102.244 103.223 1.00 166.44 ? 636 PRO   A CA  1 
ATOM   4925 C C   . PRO   A 1 611 ? 108.936 102.934 104.041 1.00 164.55 ? 636 PRO   A C   1 
ATOM   4926 O O   . PRO   A 1 611 ? 108.805 103.031 105.267 1.00 162.48 ? 636 PRO   A O   1 
ATOM   4927 C CB  . PRO   A 1 611 ? 108.216 100.778 102.940 1.00 165.20 ? 636 PRO   A CB  1 
ATOM   4928 C CG  . PRO   A 1 611 ? 108.824 100.792 101.587 1.00 162.87 ? 636 PRO   A CG  1 
ATOM   4929 C CD  . PRO   A 1 611 ? 108.106 101.865 100.826 1.00 164.43 ? 636 PRO   A CD  1 
ATOM   4930 N N   . GLU   A 1 612 ? 110.001 103.417 103.396 1.00 162.37 ? 637 GLU   A N   1 
ATOM   4931 C CA  . GLU   A 1 612 ? 111.054 104.124 104.119 1.00 162.54 ? 637 GLU   A CA  1 
ATOM   4932 C C   . GLU   A 1 612 ? 110.527 105.408 104.749 1.00 163.75 ? 637 GLU   A C   1 
ATOM   4933 O O   . GLU   A 1 612 ? 111.038 105.856 105.783 1.00 161.62 ? 637 GLU   A O   1 
ATOM   4934 C CB  . GLU   A 1 612 ? 112.221 104.431 103.180 1.00 161.30 ? 637 GLU   A CB  1 
ATOM   4935 C CG  . GLU   A 1 612 ? 112.898 103.200 102.586 1.00 159.30 ? 637 GLU   A CG  1 
ATOM   4936 C CD  . GLU   A 1 612 ? 113.614 102.357 103.626 1.00 157.99 ? 637 GLU   A CD  1 
ATOM   4937 O OE1 . GLU   A 1 612 ? 113.806 102.840 104.761 1.00 158.53 ? 637 GLU   A OE1 1 
ATOM   4938 O OE2 . GLU   A 1 612 ? 113.986 101.209 103.305 1.00 153.43 ? 637 GLU   A OE2 1 
ATOM   4939 N N   . LEU   A 1 613 ? 109.527 106.032 104.123 1.00 165.69 ? 638 LEU   A N   1 
ATOM   4940 C CA  . LEU   A 1 613 ? 108.927 107.237 104.684 1.00 166.29 ? 638 LEU   A CA  1 
ATOM   4941 C C   . LEU   A 1 613 ? 108.007 106.935 105.860 1.00 166.06 ? 638 LEU   A C   1 
ATOM   4942 O O   . LEU   A 1 613 ? 107.773 107.823 106.686 1.00 164.79 ? 638 LEU   A O   1 
ATOM   4943 C CB  . LEU   A 1 613 ? 108.155 107.985 103.593 1.00 166.20 ? 638 LEU   A CB  1 
ATOM   4944 C CG  . LEU   A 1 613 ? 107.894 109.478 103.820 1.00 164.37 ? 638 LEU   A CG  1 
ATOM   4945 C CD1 . LEU   A 1 613 ? 108.089 110.244 102.521 1.00 157.57 ? 638 LEU   A CD1 1 
ATOM   4946 C CD2 . LEU   A 1 613 ? 106.498 109.728 104.371 1.00 164.75 ? 638 LEU   A CD2 1 
ATOM   4947 N N   . GLN   A 1 614 ? 107.480 105.712 105.953 1.00 166.28 ? 639 GLN   A N   1 
ATOM   4948 C CA  . GLN   A 1 614 ? 106.515 105.392 107.004 1.00 167.70 ? 639 GLN   A CA  1 
ATOM   4949 C C   . GLN   A 1 614 ? 107.070 105.595 108.410 1.00 167.98 ? 639 GLN   A C   1 
ATOM   4950 O O   . GLN   A 1 614 ? 106.332 106.115 109.266 1.00 168.08 ? 639 GLN   A O   1 
ATOM   4951 C CB  . GLN   A 1 614 ? 105.996 103.963 106.805 1.00 168.21 ? 639 GLN   A CB  1 
ATOM   4952 C CG  . GLN   A 1 614 ? 105.110 103.796 105.586 1.00 168.65 ? 639 GLN   A CG  1 
ATOM   4953 C CD  . GLN   A 1 614 ? 104.656 102.364 105.384 1.00 168.26 ? 639 GLN   A CD  1 
ATOM   4954 O OE1 . GLN   A 1 614 ? 104.770 101.532 106.285 1.00 167.56 ? 639 GLN   A OE1 1 
ATOM   4955 N NE2 . GLN   A 1 614 ? 104.143 102.067 104.197 1.00 166.15 ? 639 GLN   A NE2 1 
ATOM   4956 N N   . PRO   A 1 615 ? 108.311 105.203 108.729 1.00 166.79 ? 640 PRO   A N   1 
ATOM   4957 C CA  . PRO   A 1 615 ? 108.851 105.532 110.059 1.00 164.81 ? 640 PRO   A CA  1 
ATOM   4958 C C   . PRO   A 1 615 ? 108.847 107.015 110.378 1.00 163.62 ? 640 PRO   A C   1 
ATOM   4959 O O   . PRO   A 1 615 ? 108.686 107.382 111.548 1.00 167.96 ? 640 PRO   A O   1 
ATOM   4960 C CB  . PRO   A 1 615 ? 110.282 104.985 109.997 1.00 162.78 ? 640 PRO   A CB  1 
ATOM   4961 C CG  . PRO   A 1 615 ? 110.216 103.869 109.047 1.00 162.06 ? 640 PRO   A CG  1 
ATOM   4962 C CD  . PRO   A 1 615 ? 109.146 104.196 108.045 1.00 163.12 ? 640 PRO   A CD  1 
ATOM   4963 N N   . LEU   A 1 616 ? 109.035 107.882 109.381 1.00 161.61 ? 641 LEU   A N   1 
ATOM   4964 C CA  . LEU   A 1 616 ? 109.045 109.317 109.645 1.00 163.30 ? 641 LEU   A CA  1 
ATOM   4965 C C   . LEU   A 1 616 ? 107.690 109.790 110.157 1.00 165.98 ? 641 LEU   A C   1 
ATOM   4966 O O   . LEU   A 1 616 ? 107.611 110.525 111.148 1.00 165.51 ? 641 LEU   A O   1 
ATOM   4967 C CB  . LEU   A 1 616 ? 109.443 110.079 108.381 1.00 161.96 ? 641 LEU   A CB  1 
ATOM   4968 C CG  . LEU   A 1 616 ? 110.858 109.796 107.868 1.00 159.25 ? 641 LEU   A CG  1 
ATOM   4969 C CD1 . LEU   A 1 616 ? 111.054 110.365 106.476 1.00 155.57 ? 641 LEU   A CD1 1 
ATOM   4970 C CD2 . LEU   A 1 616 ? 111.902 110.359 108.821 1.00 154.84 ? 641 LEU   A CD2 1 
ATOM   4971 N N   . LEU   A 1 617 ? 106.608 109.382 109.491 1.00 166.44 ? 642 LEU   A N   1 
ATOM   4972 C CA  . LEU   A 1 617 ? 105.277 109.728 109.977 1.00 168.42 ? 642 LEU   A CA  1 
ATOM   4973 C C   . LEU   A 1 617 ? 104.996 109.065 111.319 1.00 173.07 ? 642 LEU   A C   1 
ATOM   4974 O O   . LEU   A 1 617 ? 104.471 109.702 112.240 1.00 172.36 ? 642 LEU   A O   1 
ATOM   4975 C CB  . LEU   A 1 617 ? 104.215 109.329 108.951 1.00 165.23 ? 642 LEU   A CB  1 
ATOM   4976 C CG  . LEU   A 1 617 ? 104.225 110.023 107.585 1.00 163.90 ? 642 LEU   A CG  1 
ATOM   4977 C CD1 . LEU   A 1 617 ? 103.061 109.521 106.748 1.00 162.48 ? 642 LEU   A CD1 1 
ATOM   4978 C CD2 . LEU   A 1 617 ? 104.164 111.539 107.713 1.00 161.25 ? 642 LEU   A CD2 1 
ATOM   4979 N N   . GLU   A 1 618 ? 105.334 107.779 111.448 1.00 177.26 ? 643 GLU   A N   1 
ATOM   4980 C CA  . GLU   A 1 618 ? 105.104 107.081 112.709 1.00 177.93 ? 643 GLU   A CA  1 
ATOM   4981 C C   . GLU   A 1 618 ? 105.955 107.668 113.829 1.00 178.49 ? 643 GLU   A C   1 
ATOM   4982 O O   . GLU   A 1 618 ? 105.471 107.855 114.951 1.00 176.16 ? 643 GLU   A O   1 
ATOM   4983 C CB  . GLU   A 1 618 ? 105.393 105.590 112.543 1.00 177.23 ? 643 GLU   A CB  1 
ATOM   4984 C CG  . GLU   A 1 618 ? 104.415 104.870 111.629 1.00 175.34 ? 643 GLU   A CG  1 
ATOM   4985 C CD  . GLU   A 1 618 ? 104.742 103.398 111.472 1.00 175.17 ? 643 GLU   A CD  1 
ATOM   4986 O OE1 . GLU   A 1 618 ? 105.719 102.934 112.097 1.00 175.23 ? 643 GLU   A OE1 1 
ATOM   4987 O OE2 . GLU   A 1 618 ? 104.022 102.704 110.723 1.00 173.78 ? 643 GLU   A OE2 1 
ATOM   4988 N N   . GLY   A 1 619 ? 107.221 107.964 113.544 1.00 179.02 ? 644 GLY   A N   1 
ATOM   4989 C CA  . GLY   A 1 619 ? 108.118 108.533 114.525 1.00 178.15 ? 644 GLY   A CA  1 
ATOM   4990 C C   . GLY   A 1 619 ? 108.745 107.544 115.484 1.00 182.54 ? 644 GLY   A C   1 
ATOM   4991 O O   . GLY   A 1 619 ? 109.554 107.958 116.325 1.00 179.36 ? 644 GLY   A O   1 
ATOM   4992 N N   . GLU   A 1 620 ? 108.402 106.259 115.392 1.00 187.84 ? 645 GLU   A N   1 
ATOM   4993 C CA  . GLU   A 1 620 ? 108.927 105.236 116.290 1.00 190.22 ? 645 GLU   A CA  1 
ATOM   4994 C C   . GLU   A 1 620 ? 109.243 103.980 115.493 1.00 190.71 ? 645 GLU   A C   1 
ATOM   4995 O O   . GLU   A 1 620 ? 108.429 103.540 114.676 1.00 187.91 ? 645 GLU   A O   1 
ATOM   4996 C CB  . GLU   A 1 620 ? 107.927 104.915 117.407 1.00 190.70 ? 645 GLU   A CB  1 
ATOM   4997 C CG  . GLU   A 1 620 ? 107.612 106.096 118.312 1.00 189.59 ? 645 GLU   A CG  1 
ATOM   4998 C CD  . GLU   A 1 620 ? 106.638 105.741 119.418 1.00 188.46 ? 645 GLU   A CD  1 
ATOM   4999 O OE1 . GLU   A 1 620 ? 106.163 104.586 119.445 1.00 189.51 ? 645 GLU   A OE1 1 
ATOM   5000 O OE2 . GLU   A 1 620 ? 106.349 106.616 120.260 1.00 183.76 ? 645 GLU   A OE2 1 
ATOM   5001 N N   . VAL   A 1 621 ? 110.423 103.411 115.736 1.00 192.98 ? 646 VAL   A N   1 
ATOM   5002 C CA  . VAL   A 1 621 ? 110.858 102.184 115.064 1.00 193.95 ? 646 VAL   A CA  1 
ATOM   5003 C C   . VAL   A 1 621 ? 110.364 101.026 115.924 1.00 196.06 ? 646 VAL   A C   1 
ATOM   5004 O O   . VAL   A 1 621 ? 111.057 100.548 116.824 1.00 195.24 ? 646 VAL   A O   1 
ATOM   5005 C CB  . VAL   A 1 621 ? 112.371 102.149 114.858 1.00 189.58 ? 646 VAL   A CB  1 
ATOM   5006 C CG1 . VAL   A 1 621 ? 112.809 100.785 114.324 1.00 186.53 ? 646 VAL   A CG1 1 
ATOM   5007 C CG2 . VAL   A 1 621 ? 112.807 103.260 113.912 1.00 185.34 ? 646 VAL   A CG2 1 
ATOM   5008 N N   . LYS   A 1 622 ? 109.142 100.574 115.647 1.00 198.40 ? 647 LYS   A N   1 
ATOM   5009 C CA  . LYS   A 1 622 ? 108.542 99.443  116.343 1.00 198.50 ? 647 LYS   A CA  1 
ATOM   5010 C C   . LYS   A 1 622 ? 107.877 98.531  115.324 1.00 201.06 ? 647 LYS   A C   1 
ATOM   5011 O O   . LYS   A 1 622 ? 107.081 98.991  114.499 1.00 199.54 ? 647 LYS   A O   1 
ATOM   5012 C CB  . LYS   A 1 622 ? 107.527 99.918  117.388 1.00 196.34 ? 647 LYS   A CB  1 
ATOM   5013 C CG  . LYS   A 1 622 ? 108.131 100.829 118.448 1.00 194.01 ? 647 LYS   A CG  1 
ATOM   5014 C CD  . LYS   A 1 622 ? 107.102 101.265 119.476 1.00 191.56 ? 647 LYS   A CD  1 
ATOM   5015 C CE  . LYS   A 1 622 ? 107.724 102.178 120.523 1.00 189.14 ? 647 LYS   A CE  1 
ATOM   5016 N NZ  . LYS   A 1 622 ? 106.730 102.622 121.536 1.00 187.80 ? 647 LYS   A NZ  1 
ATOM   5017 N N   . GLY   A 1 623 ? 108.203 97.244  115.387 1.00 202.97 ? 648 GLY   A N   1 
ATOM   5018 C CA  . GLY   A 1 623 ? 107.603 96.271  114.486 1.00 201.99 ? 648 GLY   A CA  1 
ATOM   5019 C C   . GLY   A 1 623 ? 107.889 96.525  113.022 1.00 203.04 ? 648 GLY   A C   1 
ATOM   5020 O O   . GLY   A 1 623 ? 106.973 96.450  112.193 1.00 201.98 ? 648 GLY   A O   1 
ATOM   5021 N N   . GLY   A 1 624 ? 109.140 96.826  112.681 1.00 204.04 ? 649 GLY   A N   1 
ATOM   5022 C CA  . GLY   A 1 624 ? 109.507 97.080  111.309 1.00 202.33 ? 649 GLY   A CA  1 
ATOM   5023 C C   . GLY   A 1 624 ? 111.006 97.043  111.082 1.00 202.04 ? 649 GLY   A C   1 
ATOM   5024 O O   . GLY   A 1 624 ? 111.796 96.900  112.021 1.00 200.21 ? 649 GLY   A O   1 
ATOM   5025 N N   . PRO   A 1 625 ? 111.426 97.168  109.822 1.00 201.64 ? 650 PRO   A N   1 
ATOM   5026 C CA  . PRO   A 1 625 ? 112.861 97.134  109.518 1.00 199.20 ? 650 PRO   A CA  1 
ATOM   5027 C C   . PRO   A 1 625 ? 113.590 98.332  110.107 1.00 197.21 ? 650 PRO   A C   1 
ATOM   5028 O O   . PRO   A 1 625 ? 113.009 99.398  110.325 1.00 197.62 ? 650 PRO   A O   1 
ATOM   5029 C CB  . PRO   A 1 625 ? 112.901 97.147  107.986 1.00 195.98 ? 650 PRO   A CB  1 
ATOM   5030 C CG  . PRO   A 1 625 ? 111.625 97.792  107.581 1.00 195.77 ? 650 PRO   A CG  1 
ATOM   5031 C CD  . PRO   A 1 625 ? 110.612 97.391  108.614 1.00 197.89 ? 650 PRO   A CD  1 
ATOM   5032 N N   . GLU   A 1 626 ? 114.878 98.139  110.373 1.00 194.81 ? 651 GLU   A N   1 
ATOM   5033 C CA  . GLU   A 1 626 ? 115.682 99.204  110.952 1.00 190.06 ? 651 GLU   A CA  1 
ATOM   5034 C C   . GLU   A 1 626 ? 115.767 100.382 109.979 1.00 185.31 ? 651 GLU   A C   1 
ATOM   5035 O O   . GLU   A 1 626 ? 115.903 100.173 108.768 1.00 182.26 ? 651 GLU   A O   1 
ATOM   5036 C CB  . GLU   A 1 626 ? 117.086 98.695  111.282 1.00 189.50 ? 651 GLU   A CB  1 
ATOM   5037 C CG  . GLU   A 1 626 ? 117.114 97.563  112.295 1.00 190.04 ? 651 GLU   A CG  1 
ATOM   5038 C CD  . GLU   A 1 626 ? 118.522 97.103  112.616 1.00 189.22 ? 651 GLU   A CD  1 
ATOM   5039 O OE1 . GLU   A 1 626 ? 119.479 97.673  112.050 1.00 188.78 ? 651 GLU   A OE1 1 
ATOM   5040 O OE2 . GLU   A 1 626 ? 118.673 96.171  113.434 1.00 187.23 ? 651 GLU   A OE2 1 
ATOM   5041 N N   . PRO   A 1 627 ? 115.688 101.627 110.460 1.00 181.87 ? 652 PRO   A N   1 
ATOM   5042 C CA  . PRO   A 1 627 ? 115.727 102.766 109.536 1.00 173.74 ? 652 PRO   A CA  1 
ATOM   5043 C C   . PRO   A 1 627 ? 117.083 102.921 108.866 1.00 166.68 ? 652 PRO   A C   1 
ATOM   5044 O O   . PRO   A 1 627 ? 118.121 102.521 109.398 1.00 164.29 ? 652 PRO   A O   1 
ATOM   5045 C CB  . PRO   A 1 627 ? 115.420 103.964 110.440 1.00 170.11 ? 652 PRO   A CB  1 
ATOM   5046 C CG  . PRO   A 1 627 ? 115.919 103.550 111.765 1.00 172.91 ? 652 PRO   A CG  1 
ATOM   5047 C CD  . PRO   A 1 627 ? 115.616 102.086 111.860 1.00 180.07 ? 652 PRO   A CD  1 
ATOM   5048 N N   . THR   A 1 628 ? 117.057 103.518 107.677 1.00 159.10 ? 653 THR   A N   1 
ATOM   5049 C CA  . THR   A 1 628 ? 118.281 103.848 106.973 1.00 153.83 ? 653 THR   A CA  1 
ATOM   5050 C C   . THR   A 1 628 ? 119.010 104.979 107.700 1.00 152.64 ? 653 THR   A C   1 
ATOM   5051 O O   . THR   A 1 628 ? 118.421 105.664 108.539 1.00 153.68 ? 653 THR   A O   1 
ATOM   5052 C CB  . THR   A 1 628 ? 117.974 104.261 105.536 1.00 150.69 ? 653 THR   A CB  1 
ATOM   5053 O OG1 . THR   A 1 628 ? 117.087 105.387 105.539 1.00 148.23 ? 653 THR   A OG1 1 
ATOM   5054 C CG2 . THR   A 1 628 ? 117.331 103.113 104.772 1.00 152.23 ? 653 THR   A CG2 1 
ATOM   5055 N N   . PRO   A 1 629 ? 120.305 105.179 107.414 1.00 148.00 ? 654 PRO   A N   1 
ATOM   5056 C CA  . PRO   A 1 629 ? 121.026 106.291 108.066 1.00 144.17 ? 654 PRO   A CA  1 
ATOM   5057 C C   . PRO   A 1 629 ? 120.399 107.655 107.825 1.00 139.87 ? 654 PRO   A C   1 
ATOM   5058 O O   . PRO   A 1 629 ? 120.433 108.513 108.716 1.00 138.36 ? 654 PRO   A O   1 
ATOM   5059 C CB  . PRO   A 1 629 ? 122.430 106.201 107.453 1.00 142.23 ? 654 PRO   A CB  1 
ATOM   5060 C CG  . PRO   A 1 629 ? 122.569 104.796 107.019 1.00 143.17 ? 654 PRO   A CG  1 
ATOM   5061 C CD  . PRO   A 1 629 ? 121.207 104.359 106.585 1.00 145.59 ? 654 PRO   A CD  1 
ATOM   5062 N N   . LEU   A 1 630 ? 119.832 107.880 106.639 1.00 137.74 ? 655 LEU   A N   1 
ATOM   5063 C CA  . LEU   A 1 630 ? 119.198 109.163 106.350 1.00 138.11 ? 655 LEU   A CA  1 
ATOM   5064 C C   . LEU   A 1 630 ? 118.014 109.412 107.276 1.00 141.24 ? 655 LEU   A C   1 
ATOM   5065 O O   . LEU   A 1 630 ? 117.855 110.516 107.814 1.00 142.14 ? 655 LEU   A O   1 
ATOM   5066 C CB  . LEU   A 1 630 ? 118.759 109.196 104.885 1.00 137.28 ? 655 LEU   A CB  1 
ATOM   5067 C CG  . LEU   A 1 630 ? 118.520 110.548 104.207 1.00 136.13 ? 655 LEU   A CG  1 
ATOM   5068 C CD1 . LEU   A 1 630 ? 118.579 110.358 102.695 1.00 130.96 ? 655 LEU   A CD1 1 
ATOM   5069 C CD2 . LEU   A 1 630 ? 117.192 111.176 104.624 1.00 136.39 ? 655 LEU   A CD2 1 
ATOM   5070 N N   . VAL   A 1 631 ? 117.175 108.394 107.477 1.00 141.95 ? 656 VAL   A N   1 
ATOM   5071 C CA  . VAL   A 1 631 ? 116.013 108.545 108.346 1.00 142.31 ? 656 VAL   A CA  1 
ATOM   5072 C C   . VAL   A 1 631 ? 116.455 108.801 109.780 1.00 141.79 ? 656 VAL   A C   1 
ATOM   5073 O O   . VAL   A 1 631 ? 115.879 109.642 110.483 1.00 143.65 ? 656 VAL   A O   1 
ATOM   5074 C CB  . VAL   A 1 631 ? 115.110 107.302 108.243 1.00 149.01 ? 656 VAL   A CB  1 
ATOM   5075 C CG1 . VAL   A 1 631 ? 113.991 107.366 109.276 1.00 149.84 ? 656 VAL   A CG1 1 
ATOM   5076 C CG2 . VAL   A 1 631 ? 114.537 107.174 106.834 1.00 148.76 ? 656 VAL   A CG2 1 
ATOM   5077 N N   . GLN   A 1 632 ? 117.474 108.071 110.239 1.00 140.72 ? 657 GLN   A N   1 
ATOM   5078 C CA  . GLN   A 1 632 ? 117.987 108.283 111.587 1.00 144.30 ? 657 GLN   A CA  1 
ATOM   5079 C C   . GLN   A 1 632 ? 118.514 109.700 111.754 1.00 142.49 ? 657 GLN   A C   1 
ATOM   5080 O O   . GLN   A 1 632 ? 118.261 110.349 112.776 1.00 143.27 ? 657 GLN   A O   1 
ATOM   5081 C CB  . GLN   A 1 632 ? 119.090 107.270 111.894 1.00 147.34 ? 657 GLN   A CB  1 
ATOM   5082 C CG  . GLN   A 1 632 ? 118.633 105.825 111.875 1.00 151.55 ? 657 GLN   A CG  1 
ATOM   5083 C CD  . GLN   A 1 632 ? 119.785 104.846 111.987 1.00 153.10 ? 657 GLN   A CD  1 
ATOM   5084 O OE1 . GLN   A 1 632 ? 120.798 105.132 112.622 1.00 149.92 ? 657 GLN   A OE1 1 
ATOM   5085 N NE2 . GLN   A 1 632 ? 119.637 103.683 111.359 1.00 157.45 ? 657 GLN   A NE2 1 
ATOM   5086 N N   . THR   A 1 633 ? 119.251 110.196 110.758 1.00 137.15 ? 658 THR   A N   1 
ATOM   5087 C CA  . THR   A 1 633 ? 119.779 111.552 110.833 1.00 135.19 ? 658 THR   A CA  1 
ATOM   5088 C C   . THR   A 1 633 ? 118.655 112.577 110.876 1.00 135.31 ? 658 THR   A C   1 
ATOM   5089 O O   . THR   A 1 633 ? 118.715 113.543 111.647 1.00 137.47 ? 658 THR   A O   1 
ATOM   5090 C CB  . THR   A 1 633 ? 120.703 111.817 109.646 1.00 135.09 ? 658 THR   A CB  1 
ATOM   5091 O OG1 . THR   A 1 633 ? 121.722 110.811 109.599 1.00 134.51 ? 658 THR   A OG1 1 
ATOM   5092 C CG2 . THR   A 1 633 ? 121.355 113.190 109.763 1.00 133.50 ? 658 THR   A CG2 1 
ATOM   5093 N N   . PHE   A 1 634 ? 117.620 112.388 110.054 1.00 133.05 ? 659 PHE   A N   1 
ATOM   5094 C CA  . PHE   A 1 634 ? 116.501 113.325 110.055 1.00 133.44 ? 659 PHE   A CA  1 
ATOM   5095 C C   . PHE   A 1 634 ? 115.792 113.335 111.403 1.00 135.91 ? 659 PHE   A C   1 
ATOM   5096 O O   . PHE   A 1 634 ? 115.475 114.406 111.940 1.00 137.39 ? 659 PHE   A O   1 
ATOM   5097 C CB  . PHE   A 1 634 ? 115.520 112.970 108.938 1.00 133.55 ? 659 PHE   A CB  1 
ATOM   5098 C CG  . PHE   A 1 634 ? 114.377 113.935 108.803 1.00 132.86 ? 659 PHE   A CG  1 
ATOM   5099 C CD1 . PHE   A 1 634 ? 114.510 115.082 108.043 1.00 131.52 ? 659 PHE   A CD1 1 
ATOM   5100 C CD2 . PHE   A 1 634 ? 113.167 113.690 109.426 1.00 135.42 ? 659 PHE   A CD2 1 
ATOM   5101 C CE1 . PHE   A 1 634 ? 113.461 115.969 107.913 1.00 131.28 ? 659 PHE   A CE1 1 
ATOM   5102 C CE2 . PHE   A 1 634 ? 112.116 114.574 109.299 1.00 135.68 ? 659 PHE   A CE2 1 
ATOM   5103 C CZ  . PHE   A 1 634 ? 112.264 115.715 108.541 1.00 134.56 ? 659 PHE   A CZ  1 
ATOM   5104 N N   . LEU   A 1 635 ? 115.533 112.152 111.965 1.00 137.74 ? 660 LEU   A N   1 
ATOM   5105 C CA  . LEU   A 1 635 ? 114.867 112.086 113.261 1.00 140.17 ? 660 LEU   A CA  1 
ATOM   5106 C C   . LEU   A 1 635 ? 115.720 112.724 114.348 1.00 139.15 ? 660 LEU   A C   1 
ATOM   5107 O O   . LEU   A 1 635 ? 115.202 113.441 115.214 1.00 139.25 ? 660 LEU   A O   1 
ATOM   5108 C CB  . LEU   A 1 635 ? 114.542 110.634 113.614 1.00 142.03 ? 660 LEU   A CB  1 
ATOM   5109 C CG  . LEU   A 1 635 ? 113.505 109.922 112.738 1.00 145.22 ? 660 LEU   A CG  1 
ATOM   5110 C CD1 . LEU   A 1 635 ? 113.418 108.451 113.116 1.00 145.66 ? 660 LEU   A CD1 1 
ATOM   5111 C CD2 . LEU   A 1 635 ? 112.136 110.580 112.848 1.00 145.48 ? 660 LEU   A CD2 1 
ATOM   5112 N N   . ARG   A 1 636 ? 117.032 112.477 114.319 1.00 138.43 ? 661 ARG   A N   1 
ATOM   5113 C CA  . ARG   A 1 636 ? 117.917 113.078 115.309 1.00 139.17 ? 661 ARG   A CA  1 
ATOM   5114 C C   . ARG   A 1 636 ? 117.917 114.595 115.193 1.00 133.57 ? 661 ARG   A C   1 
ATOM   5115 O O   . ARG   A 1 636 ? 117.882 115.300 116.208 1.00 132.73 ? 661 ARG   A O   1 
ATOM   5116 C CB  . ARG   A 1 636 ? 119.334 112.522 115.145 1.00 142.22 ? 661 ARG   A CB  1 
ATOM   5117 C CG  . ARG   A 1 636 ? 120.303 112.926 116.252 1.00 141.08 ? 661 ARG   A CG  1 
ATOM   5118 C CD  . ARG   A 1 636 ? 121.711 112.388 116.015 1.00 142.45 ? 661 ARG   A CD  1 
ATOM   5119 N NE  . ARG   A 1 636 ? 121.788 110.932 116.119 1.00 146.22 ? 661 ARG   A NE  1 
ATOM   5120 C CZ  . ARG   A 1 636 ? 121.647 110.074 115.115 1.00 146.52 ? 661 ARG   A CZ  1 
ATOM   5121 N NH1 . ARG   A 1 636 ? 121.391 110.476 113.878 1.00 144.39 ? 661 ARG   A NH1 1 
ATOM   5122 N NH2 . ARG   A 1 636 ? 121.765 108.771 115.358 1.00 145.24 ? 661 ARG   A NH2 1 
ATOM   5123 N N   . ARG   A 1 637 ? 117.962 115.118 113.965 1.00 130.79 ? 662 ARG   A N   1 
ATOM   5124 C CA  . ARG   A 1 637 ? 117.948 116.565 113.784 1.00 134.89 ? 662 ARG   A CA  1 
ATOM   5125 C C   . ARG   A 1 637 ? 116.646 117.166 114.297 1.00 137.65 ? 662 ARG   A C   1 
ATOM   5126 O O   . ARG   A 1 637 ? 116.655 118.212 114.958 1.00 140.00 ? 662 ARG   A O   1 
ATOM   5127 C CB  . ARG   A 1 637 ? 118.156 116.917 112.310 1.00 137.06 ? 662 ARG   A CB  1 
ATOM   5128 C CG  . ARG   A 1 637 ? 118.289 118.415 112.044 1.00 141.38 ? 662 ARG   A CG  1 
ATOM   5129 C CD  . ARG   A 1 637 ? 118.584 118.715 110.583 1.00 143.43 ? 662 ARG   A CD  1 
ATOM   5130 N NE  . ARG   A 1 637 ? 118.656 120.151 110.334 1.00 147.21 ? 662 ARG   A NE  1 
ATOM   5131 C CZ  . ARG   A 1 637 ? 118.864 120.710 109.148 1.00 145.99 ? 662 ARG   A CZ  1 
ATOM   5132 N NH1 . ARG   A 1 637 ? 119.025 119.983 108.053 1.00 141.00 ? 662 ARG   A NH1 1 
ATOM   5133 N NH2 . ARG   A 1 637 ? 118.911 122.036 109.057 1.00 144.37 ? 662 ARG   A NH2 1 
ATOM   5134 N N   . GLN   A 1 638 ? 115.516 116.520 113.999 1.00 135.99 ? 663 GLN   A N   1 
ATOM   5135 C CA  . GLN   A 1 638 ? 114.235 117.032 114.475 1.00 133.61 ? 663 GLN   A CA  1 
ATOM   5136 C C   . GLN   A 1 638 ? 114.174 117.025 115.997 1.00 132.78 ? 663 GLN   A C   1 
ATOM   5137 O O   . GLN   A 1 638 ? 113.721 117.999 116.614 1.00 135.01 ? 663 GLN   A O   1 
ATOM   5138 C CB  . GLN   A 1 638 ? 113.094 116.206 113.884 1.00 131.72 ? 663 GLN   A CB  1 
ATOM   5139 C CG  . GLN   A 1 638 ? 111.712 116.783 114.141 1.00 132.03 ? 663 GLN   A CG  1 
ATOM   5140 C CD  . GLN   A 1 638 ? 110.618 116.015 113.426 1.00 135.81 ? 663 GLN   A CD  1 
ATOM   5141 O OE1 . GLN   A 1 638 ? 110.892 115.103 112.646 1.00 136.81 ? 663 GLN   A OE1 1 
ATOM   5142 N NE2 . GLN   A 1 638 ? 109.369 116.381 113.690 1.00 135.37 ? 663 GLN   A NE2 1 
ATOM   5143 N N   . GLN   A 1 639 ? 114.640 115.940 116.621 1.00 130.26 ? 664 GLN   A N   1 
ATOM   5144 C CA  . GLN   A 1 639 ? 114.637 115.867 118.078 1.00 130.73 ? 664 GLN   A CA  1 
ATOM   5145 C C   . GLN   A 1 639 ? 115.534 116.937 118.686 1.00 132.08 ? 664 GLN   A C   1 
ATOM   5146 O O   . GLN   A 1 639 ? 115.165 117.574 119.679 1.00 132.67 ? 664 GLN   A O   1 
ATOM   5147 C CB  . GLN   A 1 639 ? 115.078 114.475 118.532 1.00 134.53 ? 664 GLN   A CB  1 
ATOM   5148 C CG  . GLN   A 1 639 ? 115.034 114.257 120.040 1.00 136.52 ? 664 GLN   A CG  1 
ATOM   5149 C CD  . GLN   A 1 639 ? 115.337 112.824 120.430 1.00 138.80 ? 664 GLN   A CD  1 
ATOM   5150 O OE1 . GLN   A 1 639 ? 115.462 111.948 119.575 1.00 138.58 ? 664 GLN   A OE1 1 
ATOM   5151 N NE2 . GLN   A 1 639 ? 115.459 112.579 121.730 1.00 136.40 ? 664 GLN   A NE2 1 
ATOM   5152 N N   . ARG   A 1 640 ? 116.720 117.143 118.109 1.00 132.24 ? 665 ARG   A N   1 
ATOM   5153 C CA  . ARG   A 1 640 ? 117.631 118.156 118.632 1.00 130.52 ? 665 ARG   A CA  1 
ATOM   5154 C C   . ARG   A 1 640 ? 117.032 119.550 118.511 1.00 128.96 ? 665 ARG   A C   1 
ATOM   5155 O O   . ARG   A 1 640 ? 117.135 120.362 119.439 1.00 131.18 ? 665 ARG   A O   1 
ATOM   5156 C CB  . ARG   A 1 640 ? 118.969 118.080 117.897 1.00 134.88 ? 665 ARG   A CB  1 
ATOM   5157 C CG  . ARG   A 1 640 ? 120.074 118.919 118.520 1.00 140.17 ? 665 ARG   A CG  1 
ATOM   5158 C CD  . ARG   A 1 640 ? 121.380 118.772 117.754 1.00 146.06 ? 665 ARG   A CD  1 
ATOM   5159 N NE  . ARG   A 1 640 ? 122.452 119.572 118.337 1.00 150.98 ? 665 ARG   A NE  1 
ATOM   5160 C CZ  . ARG   A 1 640 ? 123.195 119.213 119.378 1.00 152.24 ? 665 ARG   A CZ  1 
ATOM   5161 N NH1 . ARG   A 1 640 ? 123.009 118.062 120.007 1.00 152.73 ? 665 ARG   A NH1 1 
ATOM   5162 N NH2 . ARG   A 1 640 ? 124.151 120.035 119.803 1.00 150.77 ? 665 ARG   A NH2 1 
ATOM   5163 N N   . LEU   A 1 641 ? 116.408 119.851 117.369 1.00 130.01 ? 666 LEU   A N   1 
ATOM   5164 C CA  . LEU   A 1 641 ? 115.787 121.159 117.194 1.00 132.27 ? 666 LEU   A CA  1 
ATOM   5165 C C   . LEU   A 1 641 ? 114.656 121.365 118.193 1.00 133.02 ? 666 LEU   A C   1 
ATOM   5166 O O   . LEU   A 1 641 ? 114.526 122.446 118.781 1.00 132.96 ? 666 LEU   A O   1 
ATOM   5167 C CB  . LEU   A 1 641 ? 115.277 121.307 115.760 1.00 134.47 ? 666 LEU   A CB  1 
ATOM   5168 C CG  . LEU   A 1 641 ? 114.640 122.645 115.369 1.00 135.87 ? 666 LEU   A CG  1 
ATOM   5169 C CD1 . LEU   A 1 641 ? 115.617 123.800 115.544 1.00 133.60 ? 666 LEU   A CD1 1 
ATOM   5170 C CD2 . LEU   A 1 641 ? 114.136 122.587 113.936 1.00 133.01 ? 666 LEU   A CD2 1 
ATOM   5171 N N   . GLN   A 1 642 ? 113.828 120.337 118.400 1.00 133.80 ? 667 GLN   A N   1 
ATOM   5172 C CA  . GLN   A 1 642 ? 112.750 120.453 119.377 1.00 132.32 ? 667 GLN   A CA  1 
ATOM   5173 C C   . GLN   A 1 642 ? 113.302 120.657 120.782 1.00 128.21 ? 667 GLN   A C   1 
ATOM   5174 O O   . GLN   A 1 642 ? 112.760 121.450 121.560 1.00 125.90 ? 667 GLN   A O   1 
ATOM   5175 C CB  . GLN   A 1 642 ? 111.856 119.214 119.322 1.00 132.91 ? 667 GLN   A CB  1 
ATOM   5176 C CG  . GLN   A 1 642 ? 110.987 119.141 118.077 1.00 133.32 ? 667 GLN   A CG  1 
ATOM   5177 C CD  . GLN   A 1 642 ? 110.112 117.905 118.046 1.00 136.55 ? 667 GLN   A CD  1 
ATOM   5178 O OE1 . GLN   A 1 642 ? 110.070 117.136 119.006 1.00 136.17 ? 667 GLN   A OE1 1 
ATOM   5179 N NE2 . GLN   A 1 642 ? 109.405 117.708 116.938 1.00 137.49 ? 667 GLN   A NE2 1 
ATOM   5180 N N   . GLU   A 1 643 ? 114.376 119.945 121.129 1.00 127.62 ? 668 GLU   A N   1 
ATOM   5181 C CA  . GLU   A 1 643 ? 114.976 120.105 122.449 1.00 129.70 ? 668 GLU   A CA  1 
ATOM   5182 C C   . GLU   A 1 643 ? 115.511 121.518 122.640 1.00 126.53 ? 668 GLU   A C   1 
ATOM   5183 O O   . GLU   A 1 643 ? 115.326 122.121 123.703 1.00 124.25 ? 668 GLU   A O   1 
ATOM   5184 C CB  . GLU   A 1 643 ? 116.089 119.076 122.645 1.00 134.88 ? 668 GLU   A CB  1 
ATOM   5185 C CG  . GLU   A 1 643 ? 116.686 119.054 124.046 1.00 135.93 ? 668 GLU   A CG  1 
ATOM   5186 C CD  . GLU   A 1 643 ? 117.694 117.937 124.233 1.00 139.37 ? 668 GLU   A CD  1 
ATOM   5187 O OE1 . GLU   A 1 643 ? 117.927 117.176 123.270 1.00 136.47 ? 668 GLU   A OE1 1 
ATOM   5188 O OE2 . GLU   A 1 643 ? 118.253 117.819 125.343 1.00 142.26 ? 668 GLU   A OE2 1 
ATOM   5189 N N   . ILE   A 1 644 ? 116.178 122.062 121.619 1.00 128.40 ? 669 ILE   A N   1 
ATOM   5190 C CA  . ILE   A 1 644 ? 116.695 123.425 121.715 1.00 128.15 ? 669 ILE   A CA  1 
ATOM   5191 C C   . ILE   A 1 644 ? 115.547 124.415 121.872 1.00 128.02 ? 669 ILE   A C   1 
ATOM   5192 O O   . ILE   A 1 644 ? 115.620 125.352 122.679 1.00 128.80 ? 669 ILE   A O   1 
ATOM   5193 C CB  . ILE   A 1 644 ? 117.569 123.757 120.491 1.00 130.91 ? 669 ILE   A CB  1 
ATOM   5194 C CG1 . ILE   A 1 644 ? 118.847 122.907 120.498 1.00 131.03 ? 669 ILE   A CG1 1 
ATOM   5195 C CG2 . ILE   A 1 644 ? 117.916 125.248 120.471 1.00 129.52 ? 669 ILE   A CG2 1 
ATOM   5196 C CD1 . ILE   A 1 644 ? 119.575 122.864 119.165 1.00 131.18 ? 669 ILE   A CD1 1 
ATOM   5197 N N   . GLU   A 1 645 ? 114.471 124.224 121.105 1.00 129.68 ? 670 GLU   A N   1 
ATOM   5198 C CA  . GLU   A 1 645 ? 113.323 125.121 121.205 1.00 130.53 ? 670 GLU   A CA  1 
ATOM   5199 C C   . GLU   A 1 645 ? 112.699 125.062 122.593 1.00 132.01 ? 670 GLU   A C   1 
ATOM   5200 O O   . GLU   A 1 645 ? 112.327 126.097 123.159 1.00 130.43 ? 670 GLU   A O   1 
ATOM   5201 C CB  . GLU   A 1 645 ? 112.290 124.767 120.134 1.00 133.87 ? 670 GLU   A CB  1 
ATOM   5202 C CG  . GLU   A 1 645 ? 111.117 125.735 120.050 1.00 135.73 ? 670 GLU   A CG  1 
ATOM   5203 C CD  . GLU   A 1 645 ? 110.181 125.417 118.901 1.00 140.16 ? 670 GLU   A CD  1 
ATOM   5204 O OE1 . GLU   A 1 645 ? 110.447 124.441 118.168 1.00 140.64 ? 670 GLU   A OE1 1 
ATOM   5205 O OE2 . GLU   A 1 645 ? 109.179 126.142 118.730 1.00 141.15 ? 670 GLU   A OE2 1 
ATOM   5206 N N   . ARG   A 1 646 ? 112.569 123.858 123.154 1.00 129.55 ? 671 ARG   A N   1 
ATOM   5207 C CA  . ARG   A 1 646 ? 112.043 123.727 124.509 1.00 125.46 ? 671 ARG   A CA  1 
ATOM   5208 C C   . ARG   A 1 646 ? 112.961 124.405 125.517 1.00 123.14 ? 671 ARG   A C   1 
ATOM   5209 O O   . ARG   A 1 646 ? 112.490 125.029 126.475 1.00 117.89 ? 671 ARG   A O   1 
ATOM   5210 C CB  . ARG   A 1 646 ? 111.859 122.249 124.856 1.00 126.99 ? 671 ARG   A CB  1 
ATOM   5211 C CG  . ARG   A 1 646 ? 111.204 121.990 126.207 1.00 129.18 ? 671 ARG   A CG  1 
ATOM   5212 C CD  . ARG   A 1 646 ? 111.033 120.502 126.459 1.00 133.78 ? 671 ARG   A CD  1 
ATOM   5213 N NE  . ARG   A 1 646 ? 110.538 120.224 127.803 1.00 138.00 ? 671 ARG   A NE  1 
ATOM   5214 C CZ  . ARG   A 1 646 ? 110.352 119.011 128.308 1.00 140.35 ? 671 ARG   A CZ  1 
ATOM   5215 N NH1 . ARG   A 1 646 ? 110.609 117.916 127.608 1.00 139.62 ? 671 ARG   A NH1 1 
ATOM   5216 N NH2 . ARG   A 1 646 ? 109.895 118.891 129.552 1.00 138.56 ? 671 ARG   A NH2 1 
ATOM   5217 N N   . ARG   A 1 647 ? 114.277 124.284 125.323 1.00 128.35 ? 672 ARG   A N   1 
ATOM   5218 C CA  . ARG   A 1 647 ? 115.225 124.946 126.213 1.00 128.70 ? 672 ARG   A CA  1 
ATOM   5219 C C   . ARG   A 1 647 ? 115.053 126.458 126.172 1.00 123.82 ? 672 ARG   A C   1 
ATOM   5220 O O   . ARG   A 1 647 ? 115.093 127.122 127.214 1.00 120.85 ? 672 ARG   A O   1 
ATOM   5221 C CB  . ARG   A 1 647 ? 116.657 124.559 125.831 1.00 131.66 ? 672 ARG   A CB  1 
ATOM   5222 C CG  . ARG   A 1 647 ? 117.746 125.194 126.697 1.00 135.45 ? 672 ARG   A CG  1 
ATOM   5223 C CD  . ARG   A 1 647 ? 119.130 124.701 126.302 1.00 139.28 ? 672 ARG   A CD  1 
ATOM   5224 N NE  . ARG   A 1 647 ? 120.188 125.461 126.959 1.00 144.83 ? 672 ARG   A NE  1 
ATOM   5225 C CZ  . ARG   A 1 647 ? 121.487 125.318 126.723 1.00 147.02 ? 672 ARG   A CZ  1 
ATOM   5226 N NH1 . ARG   A 1 647 ? 121.943 124.440 125.842 1.00 147.27 ? 672 ARG   A NH1 1 
ATOM   5227 N NH2 . ARG   A 1 647 ? 122.353 126.077 127.388 1.00 145.75 ? 672 ARG   A NH2 1 
ATOM   5228 N N   . ARG   A 1 648 ? 114.873 127.020 124.975 1.00 125.19 ? 673 ARG   A N   1 
ATOM   5229 C CA  . ARG   A 1 648 ? 114.728 128.469 124.854 1.00 124.43 ? 673 ARG   A CA  1 
ATOM   5230 C C   . ARG   A 1 648 ? 113.499 128.970 125.603 1.00 119.30 ? 673 ARG   A C   1 
ATOM   5231 O O   . ARG   A 1 648 ? 113.557 130.000 126.284 1.00 115.85 ? 673 ARG   A O   1 
ATOM   5232 C CB  . ARG   A 1 648 ? 114.657 128.864 123.379 1.00 128.68 ? 673 ARG   A CB  1 
ATOM   5233 C CG  . ARG   A 1 648 ? 115.971 128.679 122.635 1.00 132.68 ? 673 ARG   A CG  1 
ATOM   5234 C CD  . ARG   A 1 648 ? 115.810 128.911 121.142 1.00 136.08 ? 673 ARG   A CD  1 
ATOM   5235 N NE  . ARG   A 1 648 ? 117.035 128.608 120.409 1.00 138.40 ? 673 ARG   A NE  1 
ATOM   5236 C CZ  . ARG   A 1 648 ? 117.181 128.718 119.094 1.00 136.54 ? 673 ARG   A CZ  1 
ATOM   5237 N NH1 . ARG   A 1 648 ? 116.192 129.132 118.315 1.00 133.26 ? 673 ARG   A NH1 1 
ATOM   5238 N NH2 . ARG   A 1 648 ? 118.350 128.405 118.544 1.00 134.66 ? 673 ARG   A NH2 1 
ATOM   5239 N N   . ASN   A 1 649 ? 112.380 128.256 125.492 1.00 119.63 ? 674 ASN   A N   1 
ATOM   5240 C CA  . ASN   A 1 649 ? 111.129 128.659 126.137 1.00 119.68 ? 674 ASN   A CA  1 
ATOM   5241 C C   . ASN   A 1 649 ? 111.074 128.101 127.560 1.00 114.30 ? 674 ASN   A C   1 
ATOM   5242 O O   . ASN   A 1 649 ? 110.295 127.203 127.886 1.00 113.76 ? 674 ASN   A O   1 
ATOM   5243 C CB  . ASN   A 1 649 ? 109.938 128.194 125.310 1.00 124.17 ? 674 ASN   A CB  1 
ATOM   5244 C CG  . ASN   A 1 649 ? 110.003 128.675 123.875 1.00 129.64 ? 674 ASN   A CG  1 
ATOM   5245 O OD1 . ASN   A 1 649 ? 110.575 129.725 123.586 1.00 130.08 ? 674 ASN   A OD1 1 
ATOM   5246 N ND2 . ASN   A 1 649 ? 109.415 127.905 122.966 1.00 130.19 ? 674 ASN   A ND2 1 
ATOM   5247 N N   . THR   A 1 650 ? 111.936 128.661 128.415 1.00 111.53 ? 675 THR   A N   1 
ATOM   5248 C CA  . THR   A 1 650 ? 112.026 128.290 129.824 1.00 108.29 ? 675 THR   A CA  1 
ATOM   5249 C C   . THR   A 1 650 ? 111.921 129.554 130.674 1.00 105.86 ? 675 THR   A C   1 
ATOM   5250 O O   . THR   A 1 650 ? 112.699 130.498 130.455 1.00 107.95 ? 675 THR   A O   1 
ATOM   5251 C CB  . THR   A 1 650 ? 113.344 127.564 130.118 1.00 110.20 ? 675 THR   A CB  1 
ATOM   5252 O OG1 . THR   A 1 650 ? 113.464 126.420 129.264 1.00 117.12 ? 675 THR   A OG1 1 
ATOM   5253 C CG2 . THR   A 1 650 ? 113.396 127.114 131.570 1.00 107.69 ? 675 THR   A CG2 1 
ATOM   5254 N N   . PRO   A 1 651 ? 111.002 129.634 131.641 1.00 97.13  ? 676 PRO   A N   1 
ATOM   5255 C CA  . PRO   A 1 651 ? 110.911 130.854 132.453 1.00 98.22  ? 676 PRO   A CA  1 
ATOM   5256 C C   . PRO   A 1 651 ? 112.115 131.017 133.370 1.00 104.30 ? 676 PRO   A C   1 
ATOM   5257 O O   . PRO   A 1 651 ? 112.914 130.102 133.582 1.00 110.47 ? 676 PRO   A O   1 
ATOM   5258 C CB  . PRO   A 1 651 ? 109.618 130.663 133.249 1.00 98.58  ? 676 PRO   A CB  1 
ATOM   5259 C CG  . PRO   A 1 651 ? 109.428 129.212 133.309 1.00 99.03  ? 676 PRO   A CG  1 
ATOM   5260 C CD  . PRO   A 1 651 ? 109.943 128.677 132.014 1.00 95.32  ? 676 PRO   A CD  1 
ATOM   5261 N N   . PHE   A 1 652 ? 112.230 132.227 133.924 1.00 99.23  ? 677 PHE   A N   1 
ATOM   5262 C CA  . PHE   A 1 652 ? 113.407 132.595 134.707 1.00 100.33 ? 677 PHE   A CA  1 
ATOM   5263 C C   . PHE   A 1 652 ? 113.503 131.801 136.007 1.00 102.65 ? 677 PHE   A C   1 
ATOM   5264 O O   . PHE   A 1 652 ? 114.595 131.361 136.393 1.00 107.68 ? 677 PHE   A O   1 
ATOM   5265 C CB  . PHE   A 1 652 ? 113.372 134.094 134.996 1.00 100.94 ? 677 PHE   A CB  1 
ATOM   5266 C CG  . PHE   A 1 652 ? 114.391 134.546 135.999 1.00 109.11 ? 677 PHE   A CG  1 
ATOM   5267 C CD1 . PHE   A 1 652 ? 115.721 134.690 135.641 1.00 113.12 ? 677 PHE   A CD1 1 
ATOM   5268 C CD2 . PHE   A 1 652 ? 114.017 134.844 137.297 1.00 110.49 ? 677 PHE   A CD2 1 
ATOM   5269 C CE1 . PHE   A 1 652 ? 116.660 135.111 136.564 1.00 115.95 ? 677 PHE   A CE1 1 
ATOM   5270 C CE2 . PHE   A 1 652 ? 114.949 135.265 138.224 1.00 115.57 ? 677 PHE   A CE2 1 
ATOM   5271 C CZ  . PHE   A 1 652 ? 116.273 135.400 137.856 1.00 118.46 ? 677 PHE   A CZ  1 
ATOM   5272 N N   . HIS   A 1 653 ? 112.377 131.628 136.703 1.00 96.58  ? 678 HIS   A N   1 
ATOM   5273 C CA  . HIS   A 1 653 ? 112.413 130.995 138.021 1.00 96.61  ? 678 HIS   A CA  1 
ATOM   5274 C C   . HIS   A 1 653 ? 112.907 129.555 137.938 1.00 98.43  ? 678 HIS   A C   1 
ATOM   5275 O O   . HIS   A 1 653 ? 113.636 129.092 138.824 1.00 102.74 ? 678 HIS   A O   1 
ATOM   5276 C CB  . HIS   A 1 653 ? 111.040 131.060 138.705 1.00 94.13  ? 678 HIS   A CB  1 
ATOM   5277 C CG  . HIS   A 1 653 ? 109.891 130.637 137.842 1.00 98.09  ? 678 HIS   A CG  1 
ATOM   5278 N ND1 . HIS   A 1 653 ? 109.592 129.317 137.585 1.00 105.63 ? 678 HIS   A ND1 1 
ATOM   5279 C CD2 . HIS   A 1 653 ? 108.963 131.368 137.181 1.00 98.87  ? 678 HIS   A CD2 1 
ATOM   5280 C CE1 . HIS   A 1 653 ? 108.530 129.253 136.801 1.00 106.00 ? 678 HIS   A CE1 1 
ATOM   5281 N NE2 . HIS   A 1 653 ? 108.130 130.484 136.541 1.00 102.77 ? 678 HIS   A NE2 1 
ATOM   5282 N N   . GLU   A 1 654 ? 112.532 128.831 136.881 1.00 95.48  ? 679 GLU   A N   1 
ATOM   5283 C CA  . GLU   A 1 654 ? 113.038 127.472 136.715 1.00 96.58  ? 679 GLU   A CA  1 
ATOM   5284 C C   . GLU   A 1 654 ? 114.551 127.469 136.543 1.00 96.78  ? 679 GLU   A C   1 
ATOM   5285 O O   . GLU   A 1 654 ? 115.248 126.615 137.108 1.00 101.74 ? 679 GLU   A O   1 
ATOM   5286 C CB  . GLU   A 1 654 ? 112.363 126.802 135.520 1.00 104.49 ? 679 GLU   A CB  1 
ATOM   5287 C CG  . GLU   A 1 654 ? 110.885 126.525 135.722 1.00 109.52 ? 679 GLU   A CG  1 
ATOM   5288 C CD  . GLU   A 1 654 ? 110.252 125.832 134.531 1.00 119.73 ? 679 GLU   A CD  1 
ATOM   5289 O OE1 . GLU   A 1 654 ? 110.976 125.543 133.555 1.00 120.83 ? 679 GLU   A OE1 1 
ATOM   5290 O OE2 . GLU   A 1 654 ? 109.030 125.576 134.570 1.00 120.11 ? 679 GLU   A OE2 1 
ATOM   5291 N N   . ARG   A 1 655 ? 115.078 128.420 135.770 1.00 94.11  ? 680 ARG   A N   1 
ATOM   5292 C CA  . ARG   A 1 655 ? 116.521 128.502 135.575 1.00 98.12  ? 680 ARG   A CA  1 
ATOM   5293 C C   . ARG   A 1 655 ? 117.232 128.783 136.891 1.00 92.95  ? 680 ARG   A C   1 
ATOM   5294 O O   . ARG   A 1 655 ? 118.259 128.162 137.202 1.00 93.80  ? 680 ARG   A O   1 
ATOM   5295 C CB  . ARG   A 1 655 ? 116.845 129.590 134.549 1.00 103.02 ? 680 ARG   A CB  1 
ATOM   5296 C CG  . ARG   A 1 655 ? 116.211 129.379 133.178 1.00 104.69 ? 680 ARG   A CG  1 
ATOM   5297 C CD  . ARG   A 1 655 ? 116.356 130.604 132.280 1.00 105.32 ? 680 ARG   A CD  1 
ATOM   5298 N NE  . ARG   A 1 655 ? 117.727 130.807 131.821 1.00 115.27 ? 680 ARG   A NE  1 
ATOM   5299 C CZ  . ARG   A 1 655 ? 118.653 131.531 132.441 1.00 116.76 ? 680 ARG   A CZ  1 
ATOM   5300 N NH1 . ARG   A 1 655 ? 118.409 132.151 133.586 1.00 112.23 ? 680 ARG   A NH1 1 
ATOM   5301 N NH2 . ARG   A 1 655 ? 119.862 131.636 131.897 1.00 114.02 ? 680 ARG   A NH2 1 
ATOM   5302 N N   . PHE   A 1 656 ? 116.690 129.709 137.683 1.00 86.47  ? 681 PHE   A N   1 
ATOM   5303 C CA  . PHE   A 1 656 ? 117.294 130.023 138.973 1.00 86.34  ? 681 PHE   A CA  1 
ATOM   5304 C C   . PHE   A 1 656 ? 117.268 128.813 139.900 1.00 90.66  ? 681 PHE   A C   1 
ATOM   5305 O O   . PHE   A 1 656 ? 118.255 128.524 140.594 1.00 97.11  ? 681 PHE   A O   1 
ATOM   5306 C CB  . PHE   A 1 656 ? 116.560 131.208 139.599 1.00 87.30  ? 681 PHE   A CB  1 
ATOM   5307 C CG  . PHE   A 1 656 ? 117.333 131.908 140.675 1.00 92.89  ? 681 PHE   A CG  1 
ATOM   5308 C CD1 . PHE   A 1 656 ? 118.399 132.729 140.358 1.00 95.12  ? 681 PHE   A CD1 1 
ATOM   5309 C CD2 . PHE   A 1 656 ? 116.975 131.768 142.003 1.00 95.81  ? 681 PHE   A CD2 1 
ATOM   5310 C CE1 . PHE   A 1 656 ? 119.106 133.382 141.347 1.00 96.98  ? 681 PHE   A CE1 1 
ATOM   5311 C CE2 . PHE   A 1 656 ? 117.678 132.417 142.996 1.00 98.78  ? 681 PHE   A CE2 1 
ATOM   5312 C CZ  . PHE   A 1 656 ? 118.744 133.226 142.668 1.00 97.97  ? 681 PHE   A CZ  1 
ATOM   5313 N N   . PHE   A 1 657 ? 116.151 128.082 139.912 1.00 86.00  ? 682 PHE   A N   1 
ATOM   5314 C CA  . PHE   A 1 657 ? 116.045 126.899 140.757 1.00 83.48  ? 682 PHE   A CA  1 
ATOM   5315 C C   . PHE   A 1 657 ? 117.058 125.835 140.346 1.00 88.44  ? 682 PHE   A C   1 
ATOM   5316 O O   . PHE   A 1 657 ? 117.701 125.213 141.203 1.00 92.82  ? 682 PHE   A O   1 
ATOM   5317 C CB  . PHE   A 1 657 ? 114.622 126.348 140.692 1.00 83.93  ? 682 PHE   A CB  1 
ATOM   5318 C CG  . PHE   A 1 657 ? 114.234 125.531 141.884 1.00 89.23  ? 682 PHE   A CG  1 
ATOM   5319 C CD1 . PHE   A 1 657 ? 113.891 126.144 143.075 1.00 94.12  ? 682 PHE   A CD1 1 
ATOM   5320 C CD2 . PHE   A 1 657 ? 114.201 124.151 141.813 1.00 92.61  ? 682 PHE   A CD2 1 
ATOM   5321 C CE1 . PHE   A 1 657 ? 113.530 125.395 144.176 1.00 99.88  ? 682 PHE   A CE1 1 
ATOM   5322 C CE2 . PHE   A 1 657 ? 113.840 123.396 142.909 1.00 98.34  ? 682 PHE   A CE2 1 
ATOM   5323 C CZ  . PHE   A 1 657 ? 113.504 124.018 144.093 1.00 100.90 ? 682 PHE   A CZ  1 
ATOM   5324 N N   . ARG   A 1 658 ? 117.220 125.615 139.038 1.00 86.89  ? 683 ARG   A N   1 
ATOM   5325 C CA  . ARG   A 1 658 ? 118.202 124.641 138.571 1.00 86.12  ? 683 ARG   A CA  1 
ATOM   5326 C C   . ARG   A 1 658 ? 119.618 125.054 138.958 1.00 86.03  ? 683 ARG   A C   1 
ATOM   5327 O O   . ARG   A 1 658 ? 120.433 124.211 139.356 1.00 93.21  ? 683 ARG   A O   1 
ATOM   5328 C CB  . ARG   A 1 658 ? 118.091 124.465 137.057 1.00 92.01  ? 683 ARG   A CB  1 
ATOM   5329 C CG  . ARG   A 1 658 ? 116.821 123.762 136.603 1.00 102.08 ? 683 ARG   A CG  1 
ATOM   5330 C CD  . ARG   A 1 658 ? 116.742 123.680 135.086 1.00 110.74 ? 683 ARG   A CD  1 
ATOM   5331 N NE  . ARG   A 1 658 ? 115.486 123.098 134.628 1.00 117.98 ? 683 ARG   A NE  1 
ATOM   5332 C CZ  . ARG   A 1 658 ? 115.166 122.886 133.357 1.00 117.37 ? 683 ARG   A CZ  1 
ATOM   5333 N NH1 . ARG   A 1 658 ? 115.994 123.192 132.369 1.00 115.96 ? 683 ARG   A NH1 1 
ATOM   5334 N NH2 . ARG   A 1 658 ? 113.983 122.353 133.067 1.00 115.42 ? 683 ARG   A NH2 1 
ATOM   5335 N N   . PHE   A 1 659 ? 119.927 126.348 138.840 1.00 81.27  ? 684 PHE   A N   1 
ATOM   5336 C CA  . PHE   A 1 659 ? 121.241 126.846 139.239 1.00 81.63  ? 684 PHE   A CA  1 
ATOM   5337 C C   . PHE   A 1 659 ? 121.510 126.559 140.713 1.00 83.92  ? 684 PHE   A C   1 
ATOM   5338 O O   . PHE   A 1 659 ? 122.584 126.051 141.083 1.00 88.35  ? 684 PHE   A O   1 
ATOM   5339 C CB  . PHE   A 1 659 ? 121.309 128.346 138.950 1.00 82.21  ? 684 PHE   A CB  1 
ATOM   5340 C CG  . PHE   A 1 659 ? 122.611 128.990 139.319 1.00 78.52  ? 684 PHE   A CG  1 
ATOM   5341 C CD1 . PHE   A 1 659 ? 123.682 128.962 138.447 1.00 82.78  ? 684 PHE   A CD1 1 
ATOM   5342 C CD2 . PHE   A 1 659 ? 122.753 129.653 140.522 1.00 78.35  ? 684 PHE   A CD2 1 
ATOM   5343 C CE1 . PHE   A 1 659 ? 124.877 129.564 138.778 1.00 83.80  ? 684 PHE   A CE1 1 
ATOM   5344 C CE2 . PHE   A 1 659 ? 123.942 130.256 140.858 1.00 82.42  ? 684 PHE   A CE2 1 
ATOM   5345 C CZ  . PHE   A 1 659 ? 125.006 130.213 139.986 1.00 84.84  ? 684 PHE   A CZ  1 
ATOM   5346 N N   . LEU   A 1 660 ? 120.530 126.860 141.568 1.00 82.19  ? 685 LEU   A N   1 
ATOM   5347 C CA  . LEU   A 1 660 ? 120.703 126.620 142.997 1.00 83.03  ? 685 LEU   A CA  1 
ATOM   5348 C C   . LEU   A 1 660 ? 120.891 125.136 143.290 1.00 80.67  ? 685 LEU   A C   1 
ATOM   5349 O O   . LEU   A 1 660 ? 121.745 124.759 144.105 1.00 85.99  ? 685 LEU   A O   1 
ATOM   5350 C CB  . LEU   A 1 660 ? 119.507 127.170 143.777 1.00 85.95  ? 685 LEU   A CB  1 
ATOM   5351 C CG  . LEU   A 1 660 ? 119.556 128.614 144.295 1.00 89.25  ? 685 LEU   A CG  1 
ATOM   5352 C CD1 . LEU   A 1 660 ? 120.708 128.821 145.271 1.00 90.13  ? 685 LEU   A CD1 1 
ATOM   5353 C CD2 . LEU   A 1 660 ? 119.635 129.624 143.161 1.00 89.91  ? 685 LEU   A CD2 1 
ATOM   5354 N N   . LEU   A 1 661 ? 120.104 124.277 142.637 1.00 76.67  ? 686 LEU   A N   1 
ATOM   5355 C CA  . LEU   A 1 661 ? 120.230 122.842 142.879 1.00 76.97  ? 686 LEU   A CA  1 
ATOM   5356 C C   . LEU   A 1 661 ? 121.602 122.327 142.462 1.00 80.73  ? 686 LEU   A C   1 
ATOM   5357 O O   . LEU   A 1 661 ? 122.201 121.498 143.160 1.00 86.08  ? 686 LEU   A O   1 
ATOM   5358 C CB  . LEU   A 1 661 ? 119.128 122.077 142.147 1.00 79.45  ? 686 LEU   A CB  1 
ATOM   5359 C CG  . LEU   A 1 661 ? 117.929 121.671 143.008 1.00 85.34  ? 686 LEU   A CG  1 
ATOM   5360 C CD1 . LEU   A 1 661 ? 117.218 122.884 143.584 1.00 86.80  ? 686 LEU   A CD1 1 
ATOM   5361 C CD2 . LEU   A 1 661 ? 116.964 120.820 142.201 1.00 89.09  ? 686 LEU   A CD2 1 
ATOM   5362 N N   . ARG   A 1 662 ? 122.118 122.801 141.326 1.00 82.26  ? 687 ARG   A N   1 
ATOM   5363 C CA  . ARG   A 1 662 ? 123.440 122.362 140.885 1.00 83.90  ? 687 ARG   A CA  1 
ATOM   5364 C C   . ARG   A 1 662 ? 124.520 122.779 141.876 1.00 80.51  ? 687 ARG   A C   1 
ATOM   5365 O O   . ARG   A 1 662 ? 125.425 121.991 142.199 1.00 82.71  ? 687 ARG   A O   1 
ATOM   5366 C CB  . ARG   A 1 662 ? 123.737 122.918 139.494 1.00 88.03  ? 687 ARG   A CB  1 
ATOM   5367 C CG  . ARG   A 1 662 ? 125.090 122.513 138.939 1.00 93.33  ? 687 ARG   A CG  1 
ATOM   5368 C CD  . ARG   A 1 662 ? 125.213 122.802 137.448 1.00 100.55 ? 687 ARG   A CD  1 
ATOM   5369 N NE  . ARG   A 1 662 ? 124.985 124.209 137.126 1.00 105.84 ? 687 ARG   A NE  1 
ATOM   5370 C CZ  . ARG   A 1 662 ? 123.826 124.745 136.760 1.00 102.91 ? 687 ARG   A CZ  1 
ATOM   5371 N NH1 . ARG   A 1 662 ? 122.719 124.023 136.660 1.00 97.46  ? 687 ARG   A NH1 1 
ATOM   5372 N NH2 . ARG   A 1 662 ? 123.773 126.045 136.486 1.00 99.08  ? 687 ARG   A NH2 1 
ATOM   5373 N N   . LYS   A 1 663 ? 124.448 124.015 142.376 1.00 75.51  ? 688 LYS   A N   1 
ATOM   5374 C CA  . LYS   A 1 663 ? 125.452 124.444 143.346 1.00 74.27  ? 688 LYS   A CA  1 
ATOM   5375 C C   . LYS   A 1 663 ? 125.358 123.632 144.635 1.00 74.79  ? 688 LYS   A C   1 
ATOM   5376 O O   . LYS   A 1 663 ? 126.387 123.270 145.229 1.00 78.62  ? 688 LYS   A O   1 
ATOM   5377 C CB  . LYS   A 1 663 ? 125.309 125.939 143.626 1.00 76.76  ? 688 LYS   A CB  1 
ATOM   5378 C CG  . LYS   A 1 663 ? 125.612 126.834 142.429 1.00 77.69  ? 688 LYS   A CG  1 
ATOM   5379 C CD  . LYS   A 1 663 ? 127.070 126.758 141.999 1.00 77.39  ? 688 LYS   A CD  1 
ATOM   5380 C CE  . LYS   A 1 663 ? 127.376 127.739 140.885 1.00 83.05  ? 688 LYS   A CE  1 
ATOM   5381 N NZ  . LYS   A 1 663 ? 128.774 127.598 140.393 1.00 84.04  ? 688 LYS   A NZ  1 
ATOM   5382 N N   . LEU   A 1 664 ? 124.136 123.325 145.078 1.00 74.48  ? 689 LEU   A N   1 
ATOM   5383 C CA  . LEU   A 1 664 ? 123.977 122.485 146.261 1.00 71.74  ? 689 LEU   A CA  1 
ATOM   5384 C C   . LEU   A 1 664 ? 124.588 121.109 146.036 1.00 70.51  ? 689 LEU   A C   1 
ATOM   5385 O O   . LEU   A 1 664 ? 125.210 120.541 146.943 1.00 74.06  ? 689 LEU   A O   1 
ATOM   5386 C CB  . LEU   A 1 664 ? 122.498 122.364 146.627 1.00 73.42  ? 689 LEU   A CB  1 
ATOM   5387 C CG  . LEU   A 1 664 ? 122.139 121.513 147.848 1.00 76.97  ? 689 LEU   A CG  1 
ATOM   5388 C CD1 . LEU   A 1 664 ? 122.802 122.045 149.108 1.00 79.47  ? 689 LEU   A CD1 1 
ATOM   5389 C CD2 . LEU   A 1 664 ? 120.632 121.461 148.021 1.00 79.41  ? 689 LEU   A CD2 1 
ATOM   5390 N N   . TYR   A 1 665 ? 124.418 120.558 144.831 1.00 72.11  ? 690 TYR   A N   1 
ATOM   5391 C CA  . TYR   A 1 665 ? 125.043 119.279 144.507 1.00 74.87  ? 690 TYR   A CA  1 
ATOM   5392 C C   . TYR   A 1 665 ? 126.555 119.356 144.642 1.00 71.28  ? 690 TYR   A C   1 
ATOM   5393 O O   . TYR   A 1 665 ? 127.185 118.451 145.208 1.00 75.78  ? 690 TYR   A O   1 
ATOM   5394 C CB  . TYR   A 1 665 ? 124.672 118.851 143.089 1.00 83.43  ? 690 TYR   A CB  1 
ATOM   5395 C CG  . TYR   A 1 665 ? 125.614 117.821 142.507 1.00 85.83  ? 690 TYR   A CG  1 
ATOM   5396 C CD1 . TYR   A 1 665 ? 125.617 116.515 142.969 1.00 83.85  ? 690 TYR   A CD1 1 
ATOM   5397 C CD2 . TYR   A 1 665 ? 126.498 118.156 141.492 1.00 83.90  ? 690 TYR   A CD2 1 
ATOM   5398 C CE1 . TYR   A 1 665 ? 126.475 115.574 142.439 1.00 82.92  ? 690 TYR   A CE1 1 
ATOM   5399 C CE2 . TYR   A 1 665 ? 127.358 117.220 140.957 1.00 79.99  ? 690 TYR   A CE2 1 
ATOM   5400 C CZ  . TYR   A 1 665 ? 127.342 115.933 141.434 1.00 79.52  ? 690 TYR   A CZ  1 
ATOM   5401 O OH  . TYR   A 1 665 ? 128.197 114.996 140.904 1.00 78.41  ? 690 TYR   A OH  1 
ATOM   5402 N N   . VAL   A 1 666 ? 127.155 120.429 144.121 1.00 65.74  ? 691 VAL   A N   1 
ATOM   5403 C CA  . VAL   A 1 666 ? 128.610 120.567 144.182 1.00 64.90  ? 691 VAL   A CA  1 
ATOM   5404 C C   . VAL   A 1 666 ? 129.081 120.599 145.632 1.00 66.31  ? 691 VAL   A C   1 
ATOM   5405 O O   . VAL   A 1 666 ? 130.024 119.888 146.019 1.00 71.51  ? 691 VAL   A O   1 
ATOM   5406 C CB  . VAL   A 1 666 ? 129.062 121.824 143.416 1.00 62.41  ? 691 VAL   A CB  1 
ATOM   5407 C CG1 . VAL   A 1 666 ? 130.537 122.102 143.659 1.00 61.80  ? 691 VAL   A CG1 1 
ATOM   5408 C CG2 . VAL   A 1 666 ? 128.799 121.666 141.929 1.00 69.16  ? 691 VAL   A CG2 1 
ATOM   5409 N N   . PHE   A 1 667 ? 128.418 121.410 146.461 1.00 64.50  ? 692 PHE   A N   1 
ATOM   5410 C CA  . PHE   A 1 667 ? 128.833 121.523 147.858 1.00 59.99  ? 692 PHE   A CA  1 
ATOM   5411 C C   . PHE   A 1 667 ? 128.681 120.195 148.594 1.00 64.22  ? 692 PHE   A C   1 
ATOM   5412 O O   . PHE   A 1 667 ? 129.570 119.794 149.363 1.00 70.25  ? 692 PHE   A O   1 
ATOM   5413 C CB  . PHE   A 1 667 ? 128.032 122.617 148.564 1.00 63.63  ? 692 PHE   A CB  1 
ATOM   5414 C CG  . PHE   A 1 667 ? 128.544 124.006 148.307 1.00 69.09  ? 692 PHE   A CG  1 
ATOM   5415 C CD1 . PHE   A 1 667 ? 129.664 124.475 148.962 1.00 71.38  ? 692 PHE   A CD1 1 
ATOM   5416 C CD2 . PHE   A 1 667 ? 127.902 124.843 147.418 1.00 69.88  ? 692 PHE   A CD2 1 
ATOM   5417 C CE1 . PHE   A 1 667 ? 130.134 125.748 148.729 1.00 69.52  ? 692 PHE   A CE1 1 
ATOM   5418 C CE2 . PHE   A 1 667 ? 128.370 126.114 147.182 1.00 70.24  ? 692 PHE   A CE2 1 
ATOM   5419 C CZ  . PHE   A 1 667 ? 129.486 126.567 147.838 1.00 69.36  ? 692 PHE   A CZ  1 
ATOM   5420 N N   . ARG   A 1 668 ? 127.562 119.497 148.374 1.00 61.08  ? 693 ARG   A N   1 
ATOM   5421 C CA  . ARG   A 1 668 ? 127.341 118.231 149.065 1.00 58.48  ? 693 ARG   A CA  1 
ATOM   5422 C C   . ARG   A 1 668 ? 128.385 117.198 148.670 1.00 61.08  ? 693 ARG   A C   1 
ATOM   5423 O O   . ARG   A 1 668 ? 128.907 116.472 149.529 1.00 67.92  ? 693 ARG   A O   1 
ATOM   5424 C CB  . ARG   A 1 668 ? 125.939 117.708 148.772 1.00 61.90  ? 693 ARG   A CB  1 
ATOM   5425 C CG  . ARG   A 1 668 ? 125.513 116.583 149.696 1.00 63.79  ? 693 ARG   A CG  1 
ATOM   5426 C CD  . ARG   A 1 668 ? 124.073 116.164 149.467 1.00 65.68  ? 693 ARG   A CD  1 
ATOM   5427 N NE  . ARG   A 1 668 ? 123.959 115.133 148.443 1.00 66.08  ? 693 ARG   A NE  1 
ATOM   5428 C CZ  . ARG   A 1 668 ? 124.148 113.835 148.644 1.00 69.42  ? 693 ARG   A CZ  1 
ATOM   5429 N NH1 . ARG   A 1 668 ? 124.487 113.354 149.830 1.00 67.47  ? 693 ARG   A NH1 1 
ATOM   5430 N NH2 . ARG   A 1 668 ? 123.999 112.995 147.625 1.00 75.42  ? 693 ARG   A NH2 1 
ATOM   5431 N N   . ARG   A 1 669 ? 128.706 117.116 147.376 1.00 59.42  ? 694 ARG   A N   1 
ATOM   5432 C CA  . ARG   A 1 669 ? 129.715 116.157 146.941 1.00 62.74  ? 694 ARG   A CA  1 
ATOM   5433 C C   . ARG   A 1 669 ? 131.063 116.466 147.570 1.00 63.44  ? 694 ARG   A C   1 
ATOM   5434 O O   . ARG   A 1 669 ? 131.757 115.554 148.043 1.00 71.79  ? 694 ARG   A O   1 
ATOM   5435 C CB  . ARG   A 1 669 ? 129.825 116.160 145.418 1.00 69.22  ? 694 ARG   A CB  1 
ATOM   5436 C CG  . ARG   A 1 669 ? 130.756 115.094 144.862 1.00 73.05  ? 694 ARG   A CG  1 
ATOM   5437 C CD  . ARG   A 1 669 ? 130.690 115.038 143.351 1.00 73.69  ? 694 ARG   A CD  1 
ATOM   5438 N NE  . ARG   A 1 669 ? 131.347 113.850 142.819 1.00 71.50  ? 694 ARG   A NE  1 
ATOM   5439 C CZ  . ARG   A 1 669 ? 132.643 113.743 142.556 1.00 72.96  ? 694 ARG   A CZ  1 
ATOM   5440 N NH1 . ARG   A 1 669 ? 133.489 114.737 142.784 1.00 74.00  ? 694 ARG   A NH1 1 
ATOM   5441 N NH2 . ARG   A 1 669 ? 133.107 112.604 142.052 1.00 76.95  ? 694 ARG   A NH2 1 
ATOM   5442 N N   . SER   A 1 670 ? 131.444 117.747 147.603 1.00 60.55  ? 695 SER   A N   1 
ATOM   5443 C CA  . SER   A 1 670 ? 132.725 118.114 148.200 1.00 59.63  ? 695 SER   A CA  1 
ATOM   5444 C C   . SER   A 1 670 ? 132.788 117.697 149.663 1.00 59.64  ? 695 SER   A C   1 
ATOM   5445 O O   . SER   A 1 670 ? 133.763 117.068 150.104 1.00 67.91  ? 695 SER   A O   1 
ATOM   5446 C CB  . SER   A 1 670 ? 132.953 119.618 148.064 1.00 61.02  ? 695 SER   A CB  1 
ATOM   5447 O OG  . SER   A 1 670 ? 132.942 120.013 146.705 1.00 67.56  ? 695 SER   A OG  1 
ATOM   5448 N N   . PHE   A 1 671 ? 131.736 118.007 150.426 1.00 57.12  ? 696 PHE   A N   1 
ATOM   5449 C CA  . PHE   A 1 671 ? 131.745 117.695 151.852 1.00 60.55  ? 696 PHE   A CA  1 
ATOM   5450 C C   . PHE   A 1 671 ? 131.817 116.191 152.091 1.00 64.99  ? 696 PHE   A C   1 
ATOM   5451 O O   . PHE   A 1 671 ? 132.611 115.718 152.916 1.00 69.99  ? 696 PHE   A O   1 
ATOM   5452 C CB  . PHE   A 1 671 ? 130.509 118.287 152.527 1.00 63.18  ? 696 PHE   A CB  1 
ATOM   5453 C CG  . PHE   A 1 671 ? 130.447 118.035 154.005 1.00 67.72  ? 696 PHE   A CG  1 
ATOM   5454 C CD1 . PHE   A 1 671 ? 131.202 118.793 154.882 1.00 74.42  ? 696 PHE   A CD1 1 
ATOM   5455 C CD2 . PHE   A 1 671 ? 129.634 117.043 154.519 1.00 66.94  ? 696 PHE   A CD2 1 
ATOM   5456 C CE1 . PHE   A 1 671 ? 131.147 118.564 156.243 1.00 77.75  ? 696 PHE   A CE1 1 
ATOM   5457 C CE2 . PHE   A 1 671 ? 129.575 116.809 155.876 1.00 72.87  ? 696 PHE   A CE2 1 
ATOM   5458 C CZ  . PHE   A 1 671 ? 130.331 117.570 156.739 1.00 77.70  ? 696 PHE   A CZ  1 
ATOM   5459 N N   . LEU   A 1 672 ? 130.989 115.419 151.381 1.00 62.29  ? 697 LEU   A N   1 
ATOM   5460 C CA  . LEU   A 1 672 ? 130.964 113.979 151.622 1.00 58.66  ? 697 LEU   A CA  1 
ATOM   5461 C C   . LEU   A 1 672 ? 132.286 113.323 151.239 1.00 61.66  ? 697 LEU   A C   1 
ATOM   5462 O O   . LEU   A 1 672 ? 132.779 112.442 151.959 1.00 69.24  ? 697 LEU   A O   1 
ATOM   5463 C CB  . LEU   A 1 672 ? 129.803 113.334 150.866 1.00 61.32  ? 697 LEU   A CB  1 
ATOM   5464 C CG  . LEU   A 1 672 ? 128.439 113.233 151.564 1.00 61.66  ? 697 LEU   A CG  1 
ATOM   5465 C CD1 . LEU   A 1 672 ? 128.507 112.334 152.787 1.00 63.42  ? 697 LEU   A CD1 1 
ATOM   5466 C CD2 . LEU   A 1 672 ? 127.882 114.595 151.942 1.00 63.48  ? 697 LEU   A CD2 1 
ATOM   5467 N N   . MET   A 1 673 ? 132.877 113.727 150.110 1.00 61.30  ? 698 MET   A N   1 
ATOM   5468 C CA  . MET   A 1 673 ? 134.159 113.150 149.722 1.00 63.44  ? 698 MET   A CA  1 
ATOM   5469 C C   . MET   A 1 673 ? 135.244 113.486 150.738 1.00 66.86  ? 698 MET   A C   1 
ATOM   5470 O O   . MET   A 1 673 ? 136.080 112.633 151.070 1.00 69.81  ? 698 MET   A O   1 
ATOM   5471 C CB  . MET   A 1 673 ? 134.552 113.632 148.327 1.00 66.33  ? 698 MET   A CB  1 
ATOM   5472 C CG  . MET   A 1 673 ? 133.634 113.137 147.219 1.00 68.31  ? 698 MET   A CG  1 
ATOM   5473 S SD  . MET   A 1 673 ? 133.728 111.363 146.925 1.00 80.87  ? 698 MET   A SD  1 
ATOM   5474 C CE  . MET   A 1 673 ? 135.341 111.225 146.167 1.00 75.58  ? 698 MET   A CE  1 
ATOM   5475 N N   . THR   A 1 674 ? 135.250 114.724 151.245 1.00 66.53  ? 699 THR   A N   1 
ATOM   5476 C CA  . THR   A 1 674 ? 136.227 115.086 152.268 1.00 61.41  ? 699 THR   A CA  1 
ATOM   5477 C C   . THR   A 1 674 ? 136.055 114.236 153.521 1.00 66.26  ? 699 THR   A C   1 
ATOM   5478 O O   . THR   A 1 674 ? 137.043 113.794 154.123 1.00 70.87  ? 699 THR   A O   1 
ATOM   5479 C CB  . THR   A 1 674 ? 136.099 116.568 152.609 1.00 64.47  ? 699 THR   A CB  1 
ATOM   5480 O OG1 . THR   A 1 674 ? 136.347 117.352 151.436 1.00 66.71  ? 699 THR   A OG1 1 
ATOM   5481 C CG2 . THR   A 1 674 ? 137.086 116.957 153.694 1.00 68.14  ? 699 THR   A CG2 1 
ATOM   5482 N N   . CYS   A 1 675 ? 134.806 113.997 153.930 1.00 68.90  ? 700 CYS   A N   1 
ATOM   5483 C CA  . CYS   A 1 675 ? 134.569 113.167 155.107 1.00 68.98  ? 700 CYS   A CA  1 
ATOM   5484 C C   . CYS   A 1 675 ? 135.074 111.745 154.894 1.00 68.18  ? 700 CYS   A C   1 
ATOM   5485 O O   . CYS   A 1 675 ? 135.693 111.156 155.793 1.00 75.05  ? 700 CYS   A O   1 
ATOM   5486 C CB  . CYS   A 1 675 ? 133.082 113.158 155.454 1.00 69.46  ? 700 CYS   A CB  1 
ATOM   5487 S SG  . CYS   A 1 675 ? 132.487 114.692 156.195 1.00 88.64  ? 700 CYS   A SG  1 
ATOM   5488 N N   . ILE   A 1 676 ? 134.820 111.177 153.712 1.00 63.91  ? 701 ILE   A N   1 
ATOM   5489 C CA  . ILE   A 1 676 ? 135.297 109.824 153.426 1.00 63.82  ? 701 ILE   A CA  1 
ATOM   5490 C C   . ILE   A 1 676 ? 136.819 109.775 153.482 1.00 66.32  ? 701 ILE   A C   1 
ATOM   5491 O O   . ILE   A 1 676 ? 137.406 108.840 154.045 1.00 72.41  ? 701 ILE   A O   1 
ATOM   5492 C CB  . ILE   A 1 676 ? 134.763 109.338 152.064 1.00 65.48  ? 701 ILE   A CB  1 
ATOM   5493 C CG1 . ILE   A 1 676 ? 133.247 109.135 152.126 1.00 68.16  ? 701 ILE   A CG1 1 
ATOM   5494 C CG2 . ILE   A 1 676 ? 135.454 108.038 151.651 1.00 68.32  ? 701 ILE   A CG2 1 
ATOM   5495 C CD1 . ILE   A 1 676 ? 132.574 109.035 150.773 1.00 69.52  ? 701 ILE   A CD1 1 
ATOM   5496 N N   . SER   A 1 677 ? 137.481 110.780 152.907 1.00 68.27  ? 702 SER   A N   1 
ATOM   5497 C CA  . SER   A 1 677 ? 138.942 110.801 152.922 1.00 72.48  ? 702 SER   A CA  1 
ATOM   5498 C C   . SER   A 1 677 ? 139.487 110.889 154.344 1.00 71.27  ? 702 SER   A C   1 
ATOM   5499 O O   . SER   A 1 677 ? 140.453 110.197 154.693 1.00 70.71  ? 702 SER   A O   1 
ATOM   5500 C CB  . SER   A 1 677 ? 139.452 111.972 152.084 1.00 79.04  ? 702 SER   A CB  1 
ATOM   5501 O OG  . SER   A 1 677 ? 140.776 112.319 152.449 1.00 81.48  ? 702 SER   A OG  1 
ATOM   5502 N N   . LEU   A 1 678 ? 138.889 111.744 155.177 1.00 69.64  ? 703 LEU   A N   1 
ATOM   5503 C CA  . LEU   A 1 678 ? 139.373 111.881 156.546 1.00 67.04  ? 703 LEU   A CA  1 
ATOM   5504 C C   . LEU   A 1 678 ? 139.175 110.592 157.333 1.00 69.98  ? 703 LEU   A C   1 
ATOM   5505 O O   . LEU   A 1 678 ? 140.048 110.194 158.119 1.00 72.69  ? 703 LEU   A O   1 
ATOM   5506 C CB  . LEU   A 1 678 ? 138.673 113.049 157.239 1.00 68.66  ? 703 LEU   A CB  1 
ATOM   5507 C CG  . LEU   A 1 678 ? 138.995 114.447 156.706 1.00 70.72  ? 703 LEU   A CG  1 
ATOM   5508 C CD1 . LEU   A 1 678 ? 138.084 115.478 157.353 1.00 72.68  ? 703 LEU   A CD1 1 
ATOM   5509 C CD2 . LEU   A 1 678 ? 140.449 114.808 156.938 1.00 66.84  ? 703 LEU   A CD2 1 
ATOM   5510 N N   . ARG   A 1 679 ? 138.031 109.926 157.146 1.00 71.57  ? 704 ARG   A N   1 
ATOM   5511 C CA  . ARG   A 1 679 ? 137.827 108.641 157.807 1.00 68.98  ? 704 ARG   A CA  1 
ATOM   5512 C C   . ARG   A 1 679 ? 138.867 107.628 157.353 1.00 70.13  ? 704 ARG   A C   1 
ATOM   5513 O O   . ARG   A 1 679 ? 139.386 106.855 158.167 1.00 72.95  ? 704 ARG   A O   1 
ATOM   5514 C CB  . ARG   A 1 679 ? 136.421 108.113 157.535 1.00 71.95  ? 704 ARG   A CB  1 
ATOM   5515 C CG  . ARG   A 1 679 ? 136.049 106.854 158.343 1.00 73.58  ? 704 ARG   A CG  1 
ATOM   5516 C CD  . ARG   A 1 679 ? 135.036 105.978 157.626 1.00 76.68  ? 704 ARG   A CD  1 
ATOM   5517 N NE  . ARG   A 1 679 ? 135.532 105.491 156.345 1.00 75.22  ? 704 ARG   A NE  1 
ATOM   5518 C CZ  . ARG   A 1 679 ? 134.891 104.640 155.556 1.00 84.34  ? 704 ARG   A CZ  1 
ATOM   5519 N NH1 . ARG   A 1 679 ? 133.736 104.097 155.911 1.00 87.63  ? 704 ARG   A NH1 1 
ATOM   5520 N NH2 . ARG   A 1 679 ? 135.422 104.323 154.380 1.00 87.31  ? 704 ARG   A NH2 1 
ATOM   5521 N N   . ASN   A 1 680 ? 139.179 107.611 156.055 1.00 74.66  ? 705 ASN   A N   1 
ATOM   5522 C CA  . ASN   A 1 680 ? 140.202 106.694 155.562 1.00 73.25  ? 705 ASN   A CA  1 
ATOM   5523 C C   . ASN   A 1 680 ? 141.548 106.974 156.215 1.00 71.83  ? 705 ASN   A C   1 
ATOM   5524 O O   . ASN   A 1 680 ? 142.281 106.043 156.567 1.00 69.08  ? 705 ASN   A O   1 
ATOM   5525 C CB  . ASN   A 1 680 ? 140.314 106.800 154.043 1.00 75.56  ? 705 ASN   A CB  1 
ATOM   5526 C CG  . ASN   A 1 680 ? 139.081 106.296 153.334 1.00 81.01  ? 705 ASN   A CG  1 
ATOM   5527 O OD1 . ASN   A 1 680 ? 138.011 106.189 153.929 1.00 84.46  ? 705 ASN   A OD1 1 
ATOM   5528 N ND2 . ASN   A 1 680 ? 139.223 105.980 152.053 1.00 85.17  ? 705 ASN   A ND2 1 
ATOM   5529 N N   . LEU   A 1 681 ? 141.892 108.251 156.385 1.00 72.30  ? 706 LEU   A N   1 
ATOM   5530 C CA  . LEU   A 1 681 ? 143.156 108.586 157.037 1.00 63.55  ? 706 LEU   A CA  1 
ATOM   5531 C C   . LEU   A 1 681 ? 143.177 108.121 158.486 1.00 64.34  ? 706 LEU   A C   1 
ATOM   5532 O O   . LEU   A 1 681 ? 144.171 107.550 158.946 1.00 66.33  ? 706 LEU   A O   1 
ATOM   5533 C CB  . LEU   A 1 681 ? 143.408 110.091 156.977 1.00 64.88  ? 706 LEU   A CB  1 
ATOM   5534 C CG  . LEU   A 1 681 ? 143.970 110.659 155.679 1.00 67.68  ? 706 LEU   A CG  1 
ATOM   5535 C CD1 . LEU   A 1 681 ? 143.929 112.175 155.708 1.00 66.74  ? 706 LEU   A CD1 1 
ATOM   5536 C CD2 . LEU   A 1 681 ? 145.389 110.173 155.426 1.00 70.01  ? 706 LEU   A CD2 1 
ATOM   5537 N N   . ILE   A 1 682 ? 142.091 108.354 159.223 1.00 70.72  ? 707 ILE   A N   1 
ATOM   5538 C CA  . ILE   A 1 682 ? 142.122 108.181 160.673 1.00 68.50  ? 707 ILE   A CA  1 
ATOM   5539 C C   . ILE   A 1 682 ? 141.867 106.726 161.054 1.00 70.13  ? 707 ILE   A C   1 
ATOM   5540 O O   . ILE   A 1 682 ? 142.711 106.089 161.693 1.00 72.97  ? 707 ILE   A O   1 
ATOM   5541 C CB  . ILE   A 1 682 ? 141.110 109.113 161.367 1.00 68.68  ? 707 ILE   A CB  1 
ATOM   5542 C CG1 . ILE   A 1 682 ? 141.505 110.581 161.162 1.00 70.30  ? 707 ILE   A CG1 1 
ATOM   5543 C CG2 . ILE   A 1 682 ? 141.031 108.791 162.859 1.00 68.62  ? 707 ILE   A CG2 1 
ATOM   5544 C CD1 . ILE   A 1 682 ? 140.398 111.573 161.469 1.00 74.50  ? 707 ILE   A CD1 1 
ATOM   5545 N N   . LEU   A 1 683 ? 140.710 106.190 160.671 1.00 71.98  ? 708 LEU   A N   1 
ATOM   5546 C CA  . LEU   A 1 683 ? 140.272 104.873 161.119 1.00 71.63  ? 708 LEU   A CA  1 
ATOM   5547 C C   . LEU   A 1 683 ? 140.662 103.746 160.164 1.00 70.34  ? 708 LEU   A C   1 
ATOM   5548 O O   . LEU   A 1 683 ? 140.236 102.606 160.371 1.00 73.72  ? 708 LEU   A O   1 
ATOM   5549 C CB  . LEU   A 1 683 ? 138.753 104.867 161.324 1.00 74.53  ? 708 LEU   A CB  1 
ATOM   5550 C CG  . LEU   A 1 683 ? 138.217 105.650 162.524 1.00 75.11  ? 708 LEU   A CG  1 
ATOM   5551 C CD1 . LEU   A 1 683 ? 137.897 107.091 162.157 1.00 74.21  ? 708 LEU   A CD1 1 
ATOM   5552 C CD2 . LEU   A 1 683 ? 136.989 104.962 163.093 1.00 75.26  ? 708 LEU   A CD2 1 
ATOM   5553 N N   . GLY   A 1 684 ? 141.455 104.028 159.135 1.00 69.18  ? 709 GLY   A N   1 
ATOM   5554 C CA  . GLY   A 1 684 ? 141.844 103.021 158.172 1.00 72.02  ? 709 GLY   A CA  1 
ATOM   5555 C C   . GLY   A 1 684 ? 140.827 102.855 157.057 1.00 80.50  ? 709 GLY   A C   1 
ATOM   5556 O O   . GLY   A 1 684 ? 139.748 103.452 157.050 1.00 88.02  ? 709 GLY   A O   1 
ATOM   5557 N N   . ARG   A 1 685 ? 141.191 102.008 156.092 1.00 76.51  ? 710 ARG   A N   1 
ATOM   5558 C CA  . ARG   A 1 685 ? 140.409 101.833 154.876 1.00 78.91  ? 710 ARG   A CA  1 
ATOM   5559 C C   . ARG   A 1 685 ? 139.532 100.595 155.001 1.00 79.88  ? 710 ARG   A C   1 
ATOM   5560 O O   . ARG   A 1 685 ? 140.078 99.492  155.158 1.00 89.08  ? 710 ARG   A O   1 
ATOM   5561 C CB  . ARG   A 1 685 ? 141.334 101.703 153.674 1.00 83.31  ? 710 ARG   A CB  1 
ATOM   5562 C CG  . ARG   A 1 685 ? 140.624 101.789 152.339 1.00 84.52  ? 710 ARG   A CG  1 
ATOM   5563 C CD  . ARG   A 1 685 ? 141.585 102.107 151.210 1.00 84.56  ? 710 ARG   A CD  1 
ATOM   5564 N NE  . ARG   A 1 685 ? 142.095 103.471 151.293 1.00 89.04  ? 710 ARG   A NE  1 
ATOM   5565 C CZ  . ARG   A 1 685 ? 142.915 104.030 150.412 1.00 98.94  ? 710 ARG   A CZ  1 
ATOM   5566 N NH1 . ARG   A 1 685 ? 143.348 103.373 149.347 1.00 101.85 ? 710 ARG   A NH1 1 
ATOM   5567 N NH2 . ARG   A 1 685 ? 143.311 105.285 150.604 1.00 96.17  ? 710 ARG   A NH2 1 
ATOM   5568 N N   . PRO   A 1 686 ? 138.187 100.696 154.946 1.00 77.36  ? 711 PRO   A N   1 
ATOM   5569 C CA  . PRO   A 1 686 ? 137.369 99.475  155.006 1.00 84.24  ? 711 PRO   A CA  1 
ATOM   5570 C C   . PRO   A 1 686 ? 137.392 98.664  153.721 1.00 87.14  ? 711 PRO   A C   1 
ATOM   5571 O O   . PRO   A 1 686 ? 138.141 98.974  152.789 1.00 88.28  ? 711 PRO   A O   1 
ATOM   5572 C CB  . PRO   A 1 686 ? 135.958 100.004 155.294 1.00 87.69  ? 711 PRO   A CB  1 
ATOM   5573 C CG  . PRO   A 1 686 ? 136.142 101.367 155.804 1.00 87.99  ? 711 PRO   A CG  1 
ATOM   5574 C CD  . PRO   A 1 686 ? 137.354 101.896 155.125 1.00 81.16  ? 711 PRO   A CD  1 
ATOM   5575 N N   . SER   A 1 687 ? 136.576 97.613  153.674 1.00 87.54  ? 712 SER   A N   1 
ATOM   5576 C CA  . SER   A 1 687 ? 136.504 96.753  152.502 1.00 87.12  ? 712 SER   A CA  1 
ATOM   5577 C C   . SER   A 1 687 ? 136.014 97.534  151.287 1.00 88.43  ? 712 SER   A C   1 
ATOM   5578 O O   . SER   A 1 687 ? 135.455 98.629  151.396 1.00 92.15  ? 712 SER   A O   1 
ATOM   5579 C CB  . SER   A 1 687 ? 135.576 95.568  152.765 1.00 88.44  ? 712 SER   A CB  1 
ATOM   5580 O OG  . SER   A 1 687 ? 136.038 94.793  153.857 1.00 96.04  ? 712 SER   A OG  1 
ATOM   5581 N N   . LEU   A 1 688 ? 136.237 96.947  150.109 1.00 86.30  ? 713 LEU   A N   1 
ATOM   5582 C CA  . LEU   A 1 688 ? 135.934 97.642  148.862 1.00 88.01  ? 713 LEU   A CA  1 
ATOM   5583 C C   . LEU   A 1 688 ? 134.437 97.882  148.705 1.00 87.36  ? 713 LEU   A C   1 
ATOM   5584 O O   . LEU   A 1 688 ? 134.022 98.898  148.137 1.00 90.57  ? 713 LEU   A O   1 
ATOM   5585 C CB  . LEU   A 1 688 ? 136.473 96.848  147.669 1.00 86.51  ? 713 LEU   A CB  1 
ATOM   5586 C CG  . LEU   A 1 688 ? 137.987 96.806  147.408 1.00 85.48  ? 713 LEU   A CG  1 
ATOM   5587 C CD1 . LEU   A 1 688 ? 138.558 98.203  147.213 1.00 85.64  ? 713 LEU   A CD1 1 
ATOM   5588 C CD2 . LEU   A 1 688 ? 138.740 96.072  148.509 1.00 85.96  ? 713 LEU   A CD2 1 
ATOM   5589 N N   . GLU   A 1 689 ? 133.610 96.948  149.180 1.00 84.43  ? 714 GLU   A N   1 
ATOM   5590 C CA  . GLU   A 1 689 ? 132.166 97.094  149.027 1.00 87.02  ? 714 GLU   A CA  1 
ATOM   5591 C C   . GLU   A 1 689 ? 131.651 98.315  149.780 1.00 88.95  ? 714 GLU   A C   1 
ATOM   5592 O O   . GLU   A 1 689 ? 130.823 99.073  149.259 1.00 93.32  ? 714 GLU   A O   1 
ATOM   5593 C CB  . GLU   A 1 689 ? 131.466 95.822  149.508 1.00 92.99  ? 714 GLU   A CB  1 
ATOM   5594 C CG  . GLU   A 1 689 ? 129.962 95.759  149.213 1.00 99.50  ? 714 GLU   A CG  1 
ATOM   5595 C CD  . GLU   A 1 689 ? 129.087 96.405  150.283 1.00 102.53 ? 714 GLU   A CD  1 
ATOM   5596 O OE1 . GLU   A 1 689 ? 129.607 96.801  151.348 1.00 100.74 ? 714 GLU   A OE1 1 
ATOM   5597 O OE2 . GLU   A 1 689 ? 127.864 96.514  150.053 1.00 106.06 ? 714 GLU   A OE2 1 
ATOM   5598 N N   . GLN   A 1 690 ? 132.132 98.523  151.006 1.00 87.39  ? 715 GLN   A N   1 
ATOM   5599 C CA  . GLN   A 1 690 ? 131.703 99.685  151.777 1.00 90.19  ? 715 GLN   A CA  1 
ATOM   5600 C C   . GLN   A 1 690 ? 132.158 100.979 151.117 1.00 87.57  ? 715 GLN   A C   1 
ATOM   5601 O O   . GLN   A 1 690 ? 131.409 101.964 151.083 1.00 88.14  ? 715 GLN   A O   1 
ATOM   5602 C CB  . GLN   A 1 690 ? 132.236 99.588  153.205 1.00 88.30  ? 715 GLN   A CB  1 
ATOM   5603 C CG  . GLN   A 1 690 ? 131.631 100.593 154.163 1.00 88.25  ? 715 GLN   A CG  1 
ATOM   5604 C CD  . GLN   A 1 690 ? 132.115 100.401 155.582 1.00 90.74  ? 715 GLN   A CD  1 
ATOM   5605 O OE1 . GLN   A 1 690 ? 132.949 99.539  155.853 1.00 90.91  ? 715 GLN   A OE1 1 
ATOM   5606 N NE2 . GLN   A 1 690 ? 131.592 101.205 156.500 1.00 92.19  ? 715 GLN   A NE2 1 
ATOM   5607 N N   . LEU   A 1 691 ? 133.387 100.998 150.593 1.00 84.36  ? 716 LEU   A N   1 
ATOM   5608 C CA  . LEU   A 1 691 ? 133.866 102.176 149.882 1.00 82.77  ? 716 LEU   A CA  1 
ATOM   5609 C C   . LEU   A 1 691 ? 133.000 102.469 148.667 1.00 84.80  ? 716 LEU   A C   1 
ATOM   5610 O O   . LEU   A 1 691 ? 132.660 103.628 148.403 1.00 88.58  ? 716 LEU   A O   1 
ATOM   5611 C CB  . LEU   A 1 691 ? 135.319 101.980 149.454 1.00 81.01  ? 716 LEU   A CB  1 
ATOM   5612 C CG  . LEU   A 1 691 ? 136.408 102.234 150.492 1.00 86.66  ? 716 LEU   A CG  1 
ATOM   5613 C CD1 . LEU   A 1 691 ? 137.742 101.750 149.956 1.00 88.16  ? 716 LEU   A CD1 1 
ATOM   5614 C CD2 . LEU   A 1 691 ? 136.486 103.709 150.859 1.00 84.71  ? 716 LEU   A CD2 1 
ATOM   5615 N N   . ALA   A 1 692 ? 132.639 101.432 147.912 1.00 82.11  ? 717 ALA   A N   1 
ATOM   5616 C CA  . ALA   A 1 692 ? 131.795 101.632 146.742 1.00 79.40  ? 717 ALA   A CA  1 
ATOM   5617 C C   . ALA   A 1 692 ? 130.430 102.169 147.142 1.00 78.14  ? 717 ALA   A C   1 
ATOM   5618 O O   . ALA   A 1 692 ? 129.890 103.063 146.481 1.00 83.09  ? 717 ALA   A O   1 
ATOM   5619 C CB  . ALA   A 1 692 ? 131.650 100.322 145.969 1.00 81.92  ? 717 ALA   A CB  1 
ATOM   5620 N N   . GLN   A 1 693 ? 129.858 101.641 148.225 1.00 77.34  ? 718 GLN   A N   1 
ATOM   5621 C CA  . GLN   A 1 693 ? 128.557 102.122 148.679 1.00 80.44  ? 718 GLN   A CA  1 
ATOM   5622 C C   . GLN   A 1 693 ? 128.626 103.588 149.087 1.00 79.88  ? 718 GLN   A C   1 
ATOM   5623 O O   . GLN   A 1 693 ? 127.755 104.387 148.717 1.00 81.27  ? 718 GLN   A O   1 
ATOM   5624 C CB  . GLN   A 1 693 ? 128.064 101.256 149.841 1.00 83.89  ? 718 GLN   A CB  1 
ATOM   5625 C CG  . GLN   A 1 693 ? 126.708 101.649 150.421 1.00 87.11  ? 718 GLN   A CG  1 
ATOM   5626 C CD  . GLN   A 1 693 ? 125.597 101.630 149.392 1.00 93.00  ? 718 GLN   A CD  1 
ATOM   5627 O OE1 . GLN   A 1 693 ? 125.688 100.941 148.377 1.00 93.73  ? 718 GLN   A OE1 1 
ATOM   5628 N NE2 . GLN   A 1 693 ? 124.540 102.392 149.647 1.00 92.32  ? 718 GLN   A NE2 1 
ATOM   5629 N N   . GLU   A 1 694 ? 129.659 103.963 149.845 1.00 80.95  ? 719 GLU   A N   1 
ATOM   5630 C CA  . GLU   A 1 694 ? 129.801 105.354 150.261 1.00 79.43  ? 719 GLU   A CA  1 
ATOM   5631 C C   . GLU   A 1 694 ? 130.000 106.273 149.063 1.00 79.89  ? 719 GLU   A C   1 
ATOM   5632 O O   . GLU   A 1 694 ? 129.407 107.358 148.998 1.00 82.33  ? 719 GLU   A O   1 
ATOM   5633 C CB  . GLU   A 1 694 ? 130.967 105.492 151.238 1.00 83.44  ? 719 GLU   A CB  1 
ATOM   5634 C CG  . GLU   A 1 694 ? 130.724 104.834 152.579 1.00 87.28  ? 719 GLU   A CG  1 
ATOM   5635 C CD  . GLU   A 1 694 ? 131.915 104.946 153.505 1.00 96.33  ? 719 GLU   A CD  1 
ATOM   5636 O OE1 . GLU   A 1 694 ? 132.900 105.615 153.129 1.00 95.44  ? 719 GLU   A OE1 1 
ATOM   5637 O OE2 . GLU   A 1 694 ? 131.868 104.365 154.610 1.00 102.47 ? 719 GLU   A OE2 1 
ATOM   5638 N N   . VAL   A 1 695 ? 130.830 105.860 148.104 1.00 76.34  ? 720 VAL   A N   1 
ATOM   5639 C CA  . VAL   A 1 695 ? 131.084 106.693 146.935 1.00 74.49  ? 720 VAL   A CA  1 
ATOM   5640 C C   . VAL   A 1 695 ? 129.815 106.848 146.109 1.00 77.31  ? 720 VAL   A C   1 
ATOM   5641 O O   . VAL   A 1 695 ? 129.542 107.924 145.563 1.00 81.41  ? 720 VAL   A O   1 
ATOM   5642 C CB  . VAL   A 1 695 ? 132.241 106.110 146.106 1.00 76.21  ? 720 VAL   A CB  1 
ATOM   5643 C CG1 . VAL   A 1 695 ? 132.349 106.810 144.759 1.00 79.71  ? 720 VAL   A CG1 1 
ATOM   5644 C CG2 . VAL   A 1 695 ? 133.553 106.240 146.863 1.00 79.44  ? 720 VAL   A CG2 1 
ATOM   5645 N N   . THR   A 1 696 ? 129.025 105.779 145.990 1.00 75.34  ? 721 THR   A N   1 
ATOM   5646 C CA  . THR   A 1 696 ? 127.753 105.879 145.286 1.00 72.66  ? 721 THR   A CA  1 
ATOM   5647 C C   . THR   A 1 696 ? 126.811 106.839 145.997 1.00 72.40  ? 721 THR   A C   1 
ATOM   5648 O O   . THR   A 1 696 ? 126.115 107.631 145.351 1.00 76.85  ? 721 THR   A O   1 
ATOM   5649 C CB  . THR   A 1 696 ? 127.113 104.498 145.160 1.00 77.22  ? 721 THR   A CB  1 
ATOM   5650 O OG1 . THR   A 1 696 ? 128.006 103.613 144.472 1.00 83.55  ? 721 THR   A OG1 1 
ATOM   5651 C CG2 . THR   A 1 696 ? 125.801 104.582 144.396 1.00 77.11  ? 721 THR   A CG2 1 
ATOM   5652 N N   . TYR   A 1 697 ? 126.769 106.781 147.330 1.00 72.47  ? 722 TYR   A N   1 
ATOM   5653 C CA  . TYR   A 1 697 ? 125.910 107.698 148.072 1.00 71.33  ? 722 TYR   A CA  1 
ATOM   5654 C C   . TYR   A 1 697 ? 126.366 109.142 147.920 1.00 71.68  ? 722 TYR   A C   1 
ATOM   5655 O O   . TYR   A 1 697 ? 125.535 110.056 147.927 1.00 78.28  ? 722 TYR   A O   1 
ATOM   5656 C CB  . TYR   A 1 697 ? 125.873 107.313 149.549 1.00 74.28  ? 722 TYR   A CB  1 
ATOM   5657 C CG  . TYR   A 1 697 ? 125.096 108.282 150.411 1.00 74.88  ? 722 TYR   A CG  1 
ATOM   5658 C CD1 . TYR   A 1 697 ? 123.769 108.574 150.139 1.00 74.20  ? 722 TYR   A CD1 1 
ATOM   5659 C CD2 . TYR   A 1 697 ? 125.686 108.896 151.505 1.00 74.38  ? 722 TYR   A CD2 1 
ATOM   5660 C CE1 . TYR   A 1 697 ? 123.058 109.456 150.925 1.00 75.38  ? 722 TYR   A CE1 1 
ATOM   5661 C CE2 . TYR   A 1 697 ? 124.982 109.777 152.294 1.00 74.11  ? 722 TYR   A CE2 1 
ATOM   5662 C CZ  . TYR   A 1 697 ? 123.669 110.053 152.000 1.00 75.44  ? 722 TYR   A CZ  1 
ATOM   5663 O OH  . TYR   A 1 697 ? 122.961 110.931 152.784 1.00 76.99  ? 722 TYR   A OH  1 
ATOM   5664 N N   . ALA   A 1 698 ? 127.674 109.368 147.790 1.00 68.59  ? 723 ALA   A N   1 
ATOM   5665 C CA  . ALA   A 1 698 ? 128.180 110.732 147.682 1.00 67.23  ? 723 ALA   A CA  1 
ATOM   5666 C C   . ALA   A 1 698 ? 127.698 111.414 146.407 1.00 72.68  ? 723 ALA   A C   1 
ATOM   5667 O O   . ALA   A 1 698 ? 127.308 112.586 146.432 1.00 74.24  ? 723 ALA   A O   1 
ATOM   5668 C CB  . ALA   A 1 698 ? 129.706 110.724 147.734 1.00 70.43  ? 723 ALA   A CB  1 
ATOM   5669 N N   . ASN   A 1 699 ? 127.717 110.699 145.282 1.00 75.72  ? 724 ASN   A N   1 
ATOM   5670 C CA  . ASN   A 1 699 ? 127.442 111.301 143.982 1.00 74.94  ? 724 ASN   A CA  1 
ATOM   5671 C C   . ASN   A 1 699 ? 125.962 111.541 143.713 1.00 75.69  ? 724 ASN   A C   1 
ATOM   5672 O O   . ASN   A 1 699 ? 125.637 112.137 142.681 1.00 78.35  ? 724 ASN   A O   1 
ATOM   5673 C CB  . ASN   A 1 699 ? 128.007 110.418 142.868 1.00 74.63  ? 724 ASN   A CB  1 
ATOM   5674 C CG  . ASN   A 1 699 ? 129.509 110.271 142.947 1.00 80.92  ? 724 ASN   A CG  1 
ATOM   5675 O OD1 . ASN   A 1 699 ? 130.195 111.102 143.539 1.00 84.49  ? 724 ASN   A OD1 1 
ATOM   5676 N ND2 . ASN   A 1 699 ? 130.031 109.211 142.345 1.00 81.35  ? 724 ASN   A ND2 1 
ATOM   5677 N N   . LEU   A 1 700 ? 125.067 111.088 144.587 1.00 76.94  ? 725 LEU   A N   1 
ATOM   5678 C CA  . LEU   A 1 700 ? 123.640 111.144 144.296 1.00 76.62  ? 725 LEU   A CA  1 
ATOM   5679 C C   . LEU   A 1 700 ? 123.162 112.584 144.151 1.00 82.64  ? 725 LEU   A C   1 
ATOM   5680 O O   . LEU   A 1 700 ? 123.538 113.465 144.927 1.00 86.80  ? 725 LEU   A O   1 
ATOM   5681 C CB  . LEU   A 1 700 ? 122.856 110.437 145.401 1.00 78.73  ? 725 LEU   A CB  1 
ATOM   5682 C CG  . LEU   A 1 700 ? 121.357 110.228 145.176 1.00 88.02  ? 725 LEU   A CG  1 
ATOM   5683 C CD1 . LEU   A 1 700 ? 121.100 109.307 143.992 1.00 83.98  ? 725 LEU   A CD1 1 
ATOM   5684 C CD2 . LEU   A 1 700 ? 120.711 109.672 146.435 1.00 87.38  ? 725 LEU   A CD2 1 
ATOM   5685 N N   . ARG   A 1 701 ? 122.328 112.816 143.140 1.00 86.66  ? 726 ARG   A N   1 
ATOM   5686 C CA  . ARG   A 1 701 ? 121.805 114.146 142.886 1.00 92.87  ? 726 ARG   A CA  1 
ATOM   5687 C C   . ARG   A 1 701 ? 120.834 114.545 144.005 1.00 101.37 ? 726 ARG   A C   1 
ATOM   5688 O O   . ARG   A 1 701 ? 120.126 113.690 144.544 1.00 104.21 ? 726 ARG   A O   1 
ATOM   5689 C CB  . ARG   A 1 701 ? 121.096 114.173 141.534 1.00 98.79  ? 726 ARG   A CB  1 
ATOM   5690 C CG  . ARG   A 1 701 ? 120.769 115.552 140.981 1.00 103.12 ? 726 ARG   A CG  1 
ATOM   5691 C CD  . ARG   A 1 701 ? 122.021 116.308 140.554 1.00 102.60 ? 726 ARG   A CD  1 
ATOM   5692 N NE  . ARG   A 1 701 ? 121.705 117.587 139.927 1.00 110.51 ? 726 ARG   A NE  1 
ATOM   5693 C CZ  . ARG   A 1 701 ? 122.598 118.423 139.413 1.00 109.97 ? 726 ARG   A CZ  1 
ATOM   5694 N NH1 . ARG   A 1 701 ? 123.895 118.153 139.426 1.00 104.87 ? 726 ARG   A NH1 1 
ATOM   5695 N NH2 . ARG   A 1 701 ? 122.181 119.562 138.868 1.00 104.99 ? 726 ARG   A NH2 1 
ATOM   5696 N N   . PRO   A 1 702 ? 120.787 115.849 144.395 1.00 101.10 ? 727 PRO   A N   1 
ATOM   5697 C CA  . PRO   A 1 702 ? 119.891 116.242 145.495 1.00 100.25 ? 727 PRO   A CA  1 
ATOM   5698 C C   . PRO   A 1 702 ? 118.419 115.951 145.250 1.00 109.99 ? 727 PRO   A C   1 
ATOM   5699 O O   . PRO   A 1 702 ? 117.749 115.381 146.117 1.00 109.94 ? 727 PRO   A O   1 
ATOM   5700 C CB  . PRO   A 1 702 ? 120.130 117.752 145.619 1.00 96.34  ? 727 PRO   A CB  1 
ATOM   5701 C CG  . PRO   A 1 702 ? 121.482 117.956 145.121 1.00 93.99  ? 727 PRO   A CG  1 
ATOM   5702 C CD  . PRO   A 1 702 ? 121.661 116.972 144.009 1.00 96.78  ? 727 PRO   A CD  1 
ATOM   5703 N N   . PHE   A 1 703 ? 117.911 116.337 144.082 1.00 118.07 ? 728 PHE   A N   1 
ATOM   5704 C CA  . PHE   A 1 703 ? 116.478 116.275 143.784 1.00 121.06 ? 728 PHE   A CA  1 
ATOM   5705 C C   . PHE   A 1 703 ? 115.672 117.020 144.844 1.00 114.98 ? 728 PHE   A C   1 
ATOM   5706 O O   . PHE   A 1 703 ? 116.170 117.950 145.478 1.00 109.25 ? 728 PHE   A O   1 
ATOM   5707 C CB  . PHE   A 1 703 ? 115.989 114.825 143.681 1.00 121.85 ? 728 PHE   A CB  1 
ATOM   5708 C CG  . PHE   A 1 703 ? 116.301 114.169 142.366 1.00 124.42 ? 728 PHE   A CG  1 
ATOM   5709 C CD1 . PHE   A 1 703 ? 115.524 114.427 141.250 1.00 125.18 ? 728 PHE   A CD1 1 
ATOM   5710 C CD2 . PHE   A 1 703 ? 117.363 113.289 142.248 1.00 120.65 ? 728 PHE   A CD2 1 
ATOM   5711 C CE1 . PHE   A 1 703 ? 115.803 113.824 140.039 1.00 123.68 ? 728 PHE   A CE1 1 
ATOM   5712 C CE2 . PHE   A 1 703 ? 117.647 112.682 141.039 1.00 121.08 ? 728 PHE   A CE2 1 
ATOM   5713 C CZ  . PHE   A 1 703 ? 116.866 112.951 139.934 1.00 123.16 ? 728 PHE   A CZ  1 
ATOM   5714 N N   . GLU   B 2 1   ? 145.216 107.195 129.759 1.00 123.16 ? 24  GLU   P N   1 
ATOM   5715 C CA  . GLU   B 2 1   ? 144.850 106.596 128.482 1.00 127.16 ? 24  GLU   P CA  1 
ATOM   5716 C C   . GLU   B 2 1   ? 145.693 105.354 128.213 1.00 131.98 ? 24  GLU   P C   1 
ATOM   5717 O O   . GLU   B 2 1   ? 146.906 105.359 128.421 1.00 133.98 ? 24  GLU   P O   1 
ATOM   5718 C CB  . GLU   B 2 1   ? 145.017 107.612 127.350 1.00 125.29 ? 24  GLU   P CB  1 
ATOM   5719 C CG  . GLU   B 2 1   ? 144.146 108.850 127.507 1.00 126.88 ? 24  GLU   P CG  1 
ATOM   5720 C CD  . GLU   B 2 1   ? 144.264 109.805 126.335 1.00 125.74 ? 24  GLU   P CD  1 
ATOM   5721 O OE1 . GLU   B 2 1   ? 144.963 109.467 125.358 1.00 120.76 ? 24  GLU   P OE1 1 
ATOM   5722 O OE2 . GLU   B 2 1   ? 143.657 110.895 126.392 1.00 129.07 ? 24  GLU   P OE2 1 
ATOM   5723 N N   . GLU   B 2 2   ? 145.040 104.290 127.751 1.00 134.64 ? 25  GLU   P N   1 
ATOM   5724 C CA  . GLU   B 2 2   ? 145.685 103.000 127.527 1.00 138.12 ? 25  GLU   P CA  1 
ATOM   5725 C C   . GLU   B 2 2   ? 145.001 102.333 126.335 1.00 140.21 ? 25  GLU   P C   1 
ATOM   5726 O O   . GLU   B 2 2   ? 144.261 102.977 125.585 1.00 135.70 ? 25  GLU   P O   1 
ATOM   5727 C CB  . GLU   B 2 2   ? 145.623 102.135 128.797 1.00 141.34 ? 25  GLU   P CB  1 
ATOM   5728 C CG  . GLU   B 2 2   ? 146.274 102.750 130.030 1.00 138.64 ? 25  GLU   P CG  1 
ATOM   5729 C CD  . GLU   B 2 2   ? 146.343 101.785 131.197 1.00 140.18 ? 25  GLU   P CD  1 
ATOM   5730 O OE1 . GLU   B 2 2   ? 145.779 100.675 131.088 1.00 145.10 ? 25  GLU   P OE1 1 
ATOM   5731 O OE2 . GLU   B 2 2   ? 146.961 102.136 132.224 1.00 136.60 ? 25  GLU   P OE2 1 
ATOM   5732 N N   . THR   B 2 3   ? 145.260 101.037 126.154 1.00 145.29 ? 26  THR   P N   1 
ATOM   5733 C CA  . THR   B 2 3   ? 144.699 100.161 125.123 1.00 145.74 ? 26  THR   P CA  1 
ATOM   5734 C C   . THR   B 2 3   ? 145.350 100.369 123.756 1.00 141.73 ? 26  THR   P C   1 
ATOM   5735 O O   . THR   B 2 3   ? 144.910 99.736  122.788 1.00 137.99 ? 26  THR   P O   1 
ATOM   5736 C CB  . THR   B 2 3   ? 143.176 100.314 124.956 1.00 145.55 ? 26  THR   P CB  1 
ATOM   5737 O OG1 . THR   B 2 3   ? 142.870 101.603 124.409 1.00 143.62 ? 26  THR   P OG1 1 
ATOM   5738 C CG2 . THR   B 2 3   ? 142.465 100.143 126.294 1.00 143.53 ? 26  THR   P CG2 1 
ATOM   5739 N N   . ASP   B 2 4   ? 146.366 101.224 123.635 1.00 136.57 ? 27  ASP   P N   1 
ATOM   5740 C CA  . ASP   B 2 4   ? 147.096 101.437 122.386 1.00 129.62 ? 27  ASP   P CA  1 
ATOM   5741 C C   . ASP   B 2 4   ? 146.204 101.967 121.265 1.00 124.96 ? 27  ASP   P C   1 
ATOM   5742 O O   . ASP   B 2 4   ? 146.524 101.789 120.085 1.00 121.75 ? 27  ASP   P O   1 
ATOM   5743 C CB  . ASP   B 2 4   ? 147.793 100.151 121.928 1.00 133.58 ? 27  ASP   P CB  1 
ATOM   5744 C CG  . ASP   B 2 4   ? 148.659 99.541  123.010 1.00 136.15 ? 27  ASP   P CG  1 
ATOM   5745 O OD1 . ASP   B 2 4   ? 148.796 100.160 124.086 1.00 135.68 ? 27  ASP   P OD1 1 
ATOM   5746 O OD2 . ASP   B 2 4   ? 149.199 98.438  122.785 1.00 142.53 ? 27  ASP   P OD2 1 
ATOM   5747 N N   . GLN   B 2 5   ? 145.085 102.609 121.615 1.00 124.03 ? 28  GLN   P N   1 
ATOM   5748 C CA  . GLN   B 2 5   ? 144.197 103.249 120.654 1.00 119.31 ? 28  GLN   P CA  1 
ATOM   5749 C C   . GLN   B 2 5   ? 143.949 104.717 120.959 1.00 108.95 ? 28  GLN   P C   1 
ATOM   5750 O O   . GLN   B 2 5   ? 143.466 105.437 120.078 1.00 104.44 ? 28  GLN   P O   1 
ATOM   5751 C CB  . GLN   B 2 5   ? 142.847 102.517 120.602 1.00 126.44 ? 28  GLN   P CB  1 
ATOM   5752 C CG  . GLN   B 2 5   ? 142.947 101.059 120.184 1.00 129.72 ? 28  GLN   P CG  1 
ATOM   5753 C CD  . GLN   B 2 5   ? 141.601 100.364 120.170 1.00 130.51 ? 28  GLN   P CD  1 
ATOM   5754 O OE1 . GLN   B 2 5   ? 140.566 100.986 120.408 1.00 128.95 ? 28  GLN   P OE1 1 
ATOM   5755 N NE2 . GLN   B 2 5   ? 141.608 99.065  119.893 1.00 130.84 ? 28  GLN   P NE2 1 
ATOM   5756 N N   . GLU   B 2 6   ? 144.261 105.174 122.172 1.00 102.64 ? 29  GLU   P N   1 
ATOM   5757 C CA  . GLU   B 2 6   ? 144.200 106.579 122.542 1.00 100.05 ? 29  GLU   P CA  1 
ATOM   5758 C C   . GLU   B 2 6   ? 145.578 107.214 122.668 1.00 94.59  ? 29  GLU   P C   1 
ATOM   5759 O O   . GLU   B 2 6   ? 145.665 108.409 122.969 1.00 100.13 ? 29  GLU   P O   1 
ATOM   5760 C CB  . GLU   B 2 6   ? 143.440 106.737 123.863 1.00 107.76 ? 29  GLU   P CB  1 
ATOM   5761 C CG  . GLU   B 2 6   ? 142.010 106.221 123.824 1.00 112.10 ? 29  GLU   P CG  1 
ATOM   5762 C CD  . GLU   B 2 6   ? 141.293 106.389 125.149 1.00 120.65 ? 29  GLU   P CD  1 
ATOM   5763 O OE1 . GLU   B 2 6   ? 141.897 106.950 126.087 1.00 121.84 ? 29  GLU   P OE1 1 
ATOM   5764 O OE2 . GLU   B 2 6   ? 140.126 105.957 125.254 1.00 121.79 ? 29  GLU   P OE2 1 
ATOM   5765 N N   . VAL   B 2 7   ? 146.652 106.452 122.443 1.00 84.79  ? 30  VAL   P N   1 
ATOM   5766 C CA  . VAL   B 2 7   ? 148.026 106.922 122.552 1.00 77.40  ? 30  VAL   P CA  1 
ATOM   5767 C C   . VAL   B 2 7   ? 148.765 106.836 121.220 1.00 78.46  ? 30  VAL   P C   1 
ATOM   5768 O O   . VAL   B 2 7   ? 149.946 107.171 121.149 1.00 84.13  ? 30  VAL   P O   1 
ATOM   5769 C CB  . VAL   B 2 7   ? 148.783 106.141 123.647 1.00 79.00  ? 30  VAL   P CB  1 
ATOM   5770 C CG1 . VAL   B 2 7   ? 150.062 106.874 124.081 1.00 83.65  ? 30  VAL   P CG1 1 
ATOM   5771 C CG2 . VAL   B 2 7   ? 147.866 105.871 124.843 1.00 95.71  ? 30  VAL   P CG2 1 
ATOM   5772 N N   . PHE   B 2 8   ? 148.090 106.411 120.151 1.00 72.52  ? 31  PHE   P N   1 
ATOM   5773 C CA  . PHE   B 2 8   ? 148.711 106.293 118.840 1.00 59.01  ? 31  PHE   P CA  1 
ATOM   5774 C C   . PHE   B 2 8   ? 147.665 106.581 117.775 1.00 59.42  ? 31  PHE   P C   1 
ATOM   5775 O O   . PHE   B 2 8   ? 146.500 106.207 117.925 1.00 69.58  ? 31  PHE   P O   1 
ATOM   5776 C CB  . PHE   B 2 8   ? 149.303 104.898 118.612 1.00 63.00  ? 31  PHE   P CB  1 
ATOM   5777 C CG  . PHE   B 2 8   ? 150.444 104.558 119.527 1.00 60.80  ? 31  PHE   P CG  1 
ATOM   5778 C CD1 . PHE   B 2 8   ? 151.733 104.936 119.218 1.00 58.76  ? 31  PHE   P CD1 1 
ATOM   5779 C CD2 . PHE   B 2 8   ? 150.224 103.849 120.692 1.00 70.07  ? 31  PHE   P CD2 1 
ATOM   5780 C CE1 . PHE   B 2 8   ? 152.778 104.621 120.054 1.00 59.96  ? 31  PHE   P CE1 1 
ATOM   5781 C CE2 . PHE   B 2 8   ? 151.269 103.532 121.529 1.00 69.82  ? 31  PHE   P CE2 1 
ATOM   5782 C CZ  . PHE   B 2 8   ? 152.546 103.918 121.209 1.00 62.07  ? 31  PHE   P CZ  1 
ATOM   5783 N N   . LEU   B 2 9   ? 148.093 107.247 116.706 1.00 54.87  ? 32  LEU   P N   1 
ATOM   5784 C CA  . LEU   B 2 9   ? 147.259 107.519 115.545 1.00 54.33  ? 32  LEU   P CA  1 
ATOM   5785 C C   . LEU   B 2 9   ? 147.979 107.052 114.291 1.00 56.85  ? 32  LEU   P C   1 
ATOM   5786 O O   . LEU   B 2 9   ? 149.210 107.029 114.235 1.00 61.26  ? 32  LEU   P O   1 
ATOM   5787 C CB  . LEU   B 2 9   ? 146.933 109.009 115.408 1.00 52.22  ? 32  LEU   P CB  1 
ATOM   5788 C CG  . LEU   B 2 9   ? 145.965 109.633 116.411 1.00 56.36  ? 32  LEU   P CG  1 
ATOM   5789 C CD1 . LEU   B 2 9   ? 145.865 111.121 116.150 1.00 57.68  ? 32  LEU   P CD1 1 
ATOM   5790 C CD2 . LEU   B 2 9   ? 144.593 108.987 116.338 1.00 57.20  ? 32  LEU   P CD2 1 
ATOM   5791 N N   . GLY   B 2 10  ? 147.199 106.677 113.283 1.00 55.60  ? 33  GLY   P N   1 
ATOM   5792 C CA  . GLY   B 2 10  ? 147.753 106.317 112.003 1.00 54.15  ? 33  GLY   P CA  1 
ATOM   5793 C C   . GLY   B 2 10  ? 148.248 107.555 111.281 1.00 58.15  ? 33  GLY   P C   1 
ATOM   5794 O O   . GLY   B 2 10  ? 147.965 108.681 111.699 1.00 62.58  ? 33  GLY   P O   1 
ATOM   5795 N N   . PRO   B 2 11  ? 149.011 107.382 110.203 1.00 53.66  ? 34  PRO   P N   1 
ATOM   5796 C CA  . PRO   B 2 11  ? 149.512 108.545 109.457 1.00 51.41  ? 34  PRO   P CA  1 
ATOM   5797 C C   . PRO   B 2 11  ? 148.393 109.426 108.924 1.00 54.27  ? 34  PRO   P C   1 
ATOM   5798 O O   . PRO   B 2 11  ? 148.397 110.637 109.191 1.00 59.76  ? 34  PRO   P O   1 
ATOM   5799 C CB  . PRO   B 2 11  ? 150.326 107.916 108.317 1.00 56.00  ? 34  PRO   P CB  1 
ATOM   5800 C CG  . PRO   B 2 11  ? 150.666 106.566 108.786 1.00 60.41  ? 34  PRO   P CG  1 
ATOM   5801 C CD  . PRO   B 2 11  ? 149.549 106.119 109.667 1.00 59.01  ? 34  PRO   P CD  1 
ATOM   5802 N N   . PRO   B 2 12  ? 147.422 108.892 108.165 1.00 53.34  ? 35  PRO   P N   1 
ATOM   5803 C CA  . PRO   B 2 12  ? 146.461 109.803 107.517 1.00 55.06  ? 35  PRO   P CA  1 
ATOM   5804 C C   . PRO   B 2 12  ? 145.566 110.565 108.479 1.00 55.27  ? 35  PRO   P C   1 
ATOM   5805 O O   . PRO   B 2 12  ? 145.202 111.710 108.182 1.00 62.69  ? 35  PRO   P O   1 
ATOM   5806 C CB  . PRO   B 2 12  ? 145.652 108.870 106.608 1.00 59.14  ? 35  PRO   P CB  1 
ATOM   5807 C CG  . PRO   B 2 12  ? 145.724 107.574 107.241 1.00 60.11  ? 35  PRO   P CG  1 
ATOM   5808 C CD  . PRO   B 2 12  ? 147.066 107.483 107.896 1.00 61.52  ? 35  PRO   P CD  1 
ATOM   5809 N N   . GLU   B 2 13  ? 145.198 109.984 109.618 1.00 52.80  ? 36  GLU   P N   1 
ATOM   5810 C CA  . GLU   B 2 13  ? 144.303 110.652 110.556 1.00 55.40  ? 36  GLU   P CA  1 
ATOM   5811 C C   . GLU   B 2 13  ? 145.025 111.601 111.505 1.00 53.06  ? 36  GLU   P C   1 
ATOM   5812 O O   . GLU   B 2 13  ? 144.359 112.280 112.291 1.00 53.48  ? 36  GLU   P O   1 
ATOM   5813 C CB  . GLU   B 2 13  ? 143.513 109.621 111.376 1.00 61.45  ? 36  GLU   P CB  1 
ATOM   5814 C CG  . GLU   B 2 13  ? 144.360 108.611 112.162 1.00 66.42  ? 36  GLU   P CG  1 
ATOM   5815 C CD  . GLU   B 2 13  ? 144.450 107.248 111.497 1.00 71.58  ? 36  GLU   P CD  1 
ATOM   5816 O OE1 . GLU   B 2 13  ? 144.308 107.165 110.259 1.00 66.12  ? 36  GLU   P OE1 1 
ATOM   5817 O OE2 . GLU   B 2 13  ? 144.663 106.250 112.219 1.00 72.43  ? 36  GLU   P OE2 1 
ATOM   5818 N N   . ALA   B 2 14  ? 146.356 111.668 111.449 1.00 53.56  ? 37  ALA   P N   1 
ATOM   5819 C CA  . ALA   B 2 14  ? 147.139 112.592 112.257 1.00 50.63  ? 37  ALA   P CA  1 
ATOM   5820 C C   . ALA   B 2 14  ? 147.644 113.794 111.473 1.00 49.38  ? 37  ALA   P C   1 
ATOM   5821 O O   . ALA   B 2 14  ? 148.104 114.760 112.088 1.00 57.49  ? 37  ALA   P O   1 
ATOM   5822 C CB  . ALA   B 2 14  ? 148.334 111.863 112.880 1.00 54.20  ? 37  ALA   P CB  1 
ATOM   5823 N N   . GLN   B 2 15  ? 147.573 113.756 110.141 1.00 49.48  ? 38  GLN   P N   1 
ATOM   5824 C CA  . GLN   B 2 15  ? 148.019 114.843 109.280 1.00 49.68  ? 38  GLN   P CA  1 
ATOM   5825 C C   . GLN   B 2 15  ? 146.865 115.551 108.581 1.00 54.66  ? 38  GLN   P C   1 
ATOM   5826 O O   . GLN   B 2 15  ? 147.102 116.322 107.647 1.00 61.84  ? 38  GLN   P O   1 
ATOM   5827 C CB  . GLN   B 2 15  ? 149.009 114.310 108.246 1.00 52.69  ? 38  GLN   P CB  1 
ATOM   5828 C CG  . GLN   B 2 15  ? 150.277 113.743 108.852 1.00 53.60  ? 38  GLN   P CG  1 
ATOM   5829 C CD  . GLN   B 2 15  ? 151.191 113.125 107.821 1.00 58.78  ? 38  GLN   P CD  1 
ATOM   5830 O OE1 . GLN   B 2 15  ? 152.411 113.241 107.908 1.00 61.91  ? 38  GLN   P OE1 1 
ATOM   5831 N NE2 . GLN   B 2 15  ? 150.606 112.458 106.837 1.00 64.21  ? 38  GLN   P NE2 1 
ATOM   5832 N N   . SER   B 2 16  ? 145.624 115.315 109.008 1.00 53.35  ? 39  SER   P N   1 
ATOM   5833 C CA  . SER   B 2 16  ? 144.481 115.996 108.417 1.00 52.42  ? 39  SER   P CA  1 
ATOM   5834 C C   . SER   B 2 16  ? 144.445 117.440 108.896 1.00 56.94  ? 39  SER   P C   1 
ATOM   5835 O O   . SER   B 2 16  ? 143.910 117.734 109.969 1.00 58.04  ? 39  SER   P O   1 
ATOM   5836 C CB  . SER   B 2 16  ? 143.178 115.278 108.772 1.00 51.21  ? 39  SER   P CB  1 
ATOM   5837 O OG  . SER   B 2 16  ? 142.965 115.272 110.171 1.00 57.33  ? 39  SER   P OG  1 
ATOM   5838 N N   . PHE   B 2 17  ? 145.017 118.345 108.102 1.00 59.91  ? 40  PHE   P N   1 
ATOM   5839 C CA  . PHE   B 2 17  ? 145.157 119.730 108.535 1.00 55.08  ? 40  PHE   P CA  1 
ATOM   5840 C C   . PHE   B 2 17  ? 143.812 120.442 108.572 1.00 55.48  ? 40  PHE   P C   1 
ATOM   5841 O O   . PHE   B 2 17  ? 143.517 121.170 109.526 1.00 61.91  ? 40  PHE   P O   1 
ATOM   5842 C CB  . PHE   B 2 17  ? 146.123 120.461 107.606 1.00 54.91  ? 40  PHE   P CB  1 
ATOM   5843 C CG  . PHE   B 2 17  ? 146.471 121.844 108.059 1.00 50.30  ? 40  PHE   P CG  1 
ATOM   5844 C CD1 . PHE   B 2 17  ? 147.430 122.045 109.028 1.00 48.80  ? 40  PHE   P CD1 1 
ATOM   5845 C CD2 . PHE   B 2 17  ? 145.846 122.944 107.507 1.00 53.19  ? 40  PHE   P CD2 1 
ATOM   5846 C CE1 . PHE   B 2 17  ? 147.754 123.313 109.445 1.00 52.56  ? 40  PHE   P CE1 1 
ATOM   5847 C CE2 . PHE   B 2 17  ? 146.169 124.216 107.921 1.00 53.30  ? 40  PHE   P CE2 1 
ATOM   5848 C CZ  . PHE   B 2 17  ? 147.122 124.399 108.892 1.00 52.04  ? 40  PHE   P CZ  1 
ATOM   5849 N N   . LEU   B 2 18  ? 142.984 120.240 107.553 1.00 53.97  ? 41  LEU   P N   1 
ATOM   5850 C CA  . LEU   B 2 18  ? 141.727 120.958 107.401 1.00 56.23  ? 41  LEU   P CA  1 
ATOM   5851 C C   . LEU   B 2 18  ? 140.587 120.134 107.981 1.00 66.54  ? 41  LEU   P C   1 
ATOM   5852 O O   . LEU   B 2 18  ? 140.401 118.973 107.604 1.00 68.94  ? 41  LEU   P O   1 
ATOM   5853 C CB  . LEU   B 2 18  ? 141.458 121.267 105.928 1.00 54.92  ? 41  LEU   P CB  1 
ATOM   5854 C CG  . LEU   B 2 18  ? 142.523 122.093 105.205 1.00 55.96  ? 41  LEU   P CG  1 
ATOM   5855 C CD1 . LEU   B 2 18  ? 142.208 122.176 103.727 1.00 57.21  ? 41  LEU   P CD1 1 
ATOM   5856 C CD2 . LEU   B 2 18  ? 142.630 123.484 105.803 1.00 57.73  ? 41  LEU   P CD2 1 
ATOM   5857 N N   . SER   B 2 19  ? 139.831 120.738 108.895 1.00 77.80  ? 42  SER   P N   1 
ATOM   5858 C CA  . SER   B 2 19  ? 138.667 120.112 109.508 1.00 88.18  ? 42  SER   P CA  1 
ATOM   5859 C C   . SER   B 2 19  ? 137.507 121.093 109.473 1.00 98.17  ? 42  SER   P C   1 
ATOM   5860 O O   . SER   B 2 19  ? 137.660 122.255 109.861 1.00 104.19 ? 42  SER   P O   1 
ATOM   5861 C CB  . SER   B 2 19  ? 138.960 119.688 110.950 1.00 94.05  ? 42  SER   P CB  1 
ATOM   5862 O OG  . SER   B 2 19  ? 139.352 120.798 111.738 1.00 103.21 ? 42  SER   P OG  1 
ATOM   5863 N N   . SER   B 2 20  ? 136.353 120.625 109.009 1.00 104.12 ? 43  SER   P N   1 
ATOM   5864 C CA  . SER   B 2 20  ? 135.179 121.475 108.896 1.00 111.58 ? 43  SER   P CA  1 
ATOM   5865 C C   . SER   B 2 20  ? 134.536 121.695 110.259 1.00 123.10 ? 43  SER   P C   1 
ATOM   5866 O O   . SER   B 2 20  ? 134.568 120.825 111.134 1.00 124.57 ? 43  SER   P O   1 
ATOM   5867 C CB  . SER   B 2 20  ? 134.160 120.857 107.940 1.00 111.74 ? 43  SER   P CB  1 
ATOM   5868 O OG  . SER   B 2 20  ? 132.982 121.640 107.879 1.00 118.93 ? 43  SER   P OG  1 
ATOM   5869 N N   . HIS   B 2 21  ? 133.950 122.880 110.430 1.00 133.82 ? 44  HIS   P N   1 
ATOM   5870 C CA  . HIS   B 2 21  ? 133.257 123.262 111.654 1.00 140.84 ? 44  HIS   P CA  1 
ATOM   5871 C C   . HIS   B 2 21  ? 131.891 123.822 111.292 1.00 146.93 ? 44  HIS   P C   1 
ATOM   5872 O O   . HIS   B 2 21  ? 131.781 124.661 110.391 1.00 145.03 ? 44  HIS   P O   1 
ATOM   5873 C CB  . HIS   B 2 21  ? 134.059 124.298 112.449 1.00 138.04 ? 44  HIS   P CB  1 
ATOM   5874 C CG  . HIS   B 2 21  ? 135.374 123.791 112.952 1.00 136.40 ? 44  HIS   P CG  1 
ATOM   5875 N ND1 . HIS   B 2 21  ? 136.426 123.488 112.113 1.00 130.58 ? 44  HIS   P ND1 1 
ATOM   5876 C CD2 . HIS   B 2 21  ? 135.809 123.534 114.208 1.00 135.84 ? 44  HIS   P CD2 1 
ATOM   5877 C CE1 . HIS   B 2 21  ? 137.451 123.066 112.831 1.00 128.09 ? 44  HIS   P CE1 1 
ATOM   5878 N NE2 . HIS   B 2 21  ? 137.103 123.085 114.105 1.00 133.95 ? 44  HIS   P NE2 1 
ATOM   5879 N N   . THR   B 2 22  ? 130.861 123.358 111.995 1.00 153.03 ? 45  THR   P N   1 
ATOM   5880 C CA  . THR   B 2 22  ? 129.485 123.790 111.758 1.00 154.37 ? 45  THR   P CA  1 
ATOM   5881 C C   . THR   B 2 22  ? 128.999 124.684 112.894 1.00 150.38 ? 45  THR   P C   1 
ATOM   5882 O O   . THR   B 2 22  ? 127.810 124.988 112.992 1.00 147.86 ? 45  THR   P O   1 
ATOM   5883 C CB  . THR   B 2 22  ? 128.534 122.588 111.619 1.00 153.28 ? 45  THR   P CB  1 
ATOM   5884 O OG1 . THR   B 2 22  ? 128.596 121.784 112.804 1.00 152.74 ? 45  THR   P OG1 1 
ATOM   5885 C CG2 . THR   B 2 22  ? 128.912 121.741 110.412 1.00 146.43 ? 45  THR   P CG2 1 
ATOM   5886 N N   . LEU   B 2 63  ? 137.936 125.998 122.072 1.00 168.52 ? 86  LEU   P N   1 
ATOM   5887 C CA  . LEU   B 2 63  ? 137.559 127.404 121.996 1.00 170.71 ? 86  LEU   P CA  1 
ATOM   5888 C C   . LEU   B 2 63  ? 138.400 128.139 120.958 1.00 173.60 ? 86  LEU   P C   1 
ATOM   5889 O O   . LEU   B 2 63  ? 139.510 127.713 120.636 1.00 172.77 ? 86  LEU   P O   1 
ATOM   5890 C CB  . LEU   B 2 63  ? 137.713 128.075 123.364 1.00 165.88 ? 86  LEU   P CB  1 
ATOM   5891 C CG  . LEU   B 2 63  ? 136.431 128.573 124.035 1.00 164.26 ? 86  LEU   P CG  1 
ATOM   5892 C CD1 . LEU   B 2 63  ? 136.719 128.998 125.466 1.00 159.35 ? 86  LEU   P CD1 1 
ATOM   5893 C CD2 . LEU   B 2 63  ? 135.811 129.725 123.255 1.00 163.93 ? 86  LEU   P CD2 1 
ATOM   5894 N N   . THR   B 2 64  ? 137.854 129.243 120.441 1.00 177.05 ? 87  THR   P N   1 
ATOM   5895 C CA  . THR   B 2 64  ? 138.539 130.091 119.474 1.00 178.04 ? 87  THR   P CA  1 
ATOM   5896 C C   . THR   B 2 64  ? 138.760 131.513 119.973 1.00 175.94 ? 87  THR   P C   1 
ATOM   5897 O O   . THR   B 2 64  ? 139.390 132.306 119.263 1.00 176.22 ? 87  THR   P O   1 
ATOM   5898 C CB  . THR   B 2 64  ? 137.750 130.140 118.158 1.00 178.19 ? 87  THR   P CB  1 
ATOM   5899 O OG1 . THR   B 2 64  ? 136.436 130.659 118.402 1.00 177.71 ? 87  THR   P OG1 1 
ATOM   5900 C CG2 . THR   B 2 64  ? 137.640 128.751 117.544 1.00 173.70 ? 87  THR   P CG2 1 
ATOM   5901 N N   . GLU   B 2 65  ? 138.260 131.862 121.160 1.00 173.86 ? 88  GLU   P N   1 
ATOM   5902 C CA  . GLU   B 2 65  ? 138.462 133.179 121.758 1.00 171.40 ? 88  GLU   P CA  1 
ATOM   5903 C C   . GLU   B 2 65  ? 138.804 133.039 123.234 1.00 159.61 ? 88  GLU   P C   1 
ATOM   5904 O O   . GLU   B 2 65  ? 138.304 133.787 124.081 1.00 153.47 ? 88  GLU   P O   1 
ATOM   5905 C CB  . GLU   B 2 65  ? 137.227 134.063 121.576 1.00 170.15 ? 88  GLU   P CB  1 
ATOM   5906 C CG  . GLU   B 2 65  ? 136.846 134.332 120.124 1.00 175.42 ? 88  GLU   P CG  1 
ATOM   5907 C CD  . GLU   B 2 65  ? 137.876 135.166 119.386 1.00 174.15 ? 88  GLU   P CD  1 
ATOM   5908 O OE1 . GLU   B 2 65  ? 138.764 135.745 120.046 1.00 169.68 ? 88  GLU   P OE1 1 
ATOM   5909 O OE2 . GLU   B 2 65  ? 137.797 135.244 118.142 1.00 173.63 ? 88  GLU   P OE2 1 
ATOM   5910 N N   . ARG   B 2 66  ? 139.660 132.076 123.564 1.00 155.19 ? 89  ARG   P N   1 
ATOM   5911 C CA  . ARG   B 2 66  ? 140.050 131.867 124.951 1.00 142.03 ? 89  ARG   P CA  1 
ATOM   5912 C C   . ARG   B 2 66  ? 140.984 132.977 125.414 1.00 134.82 ? 89  ARG   P C   1 
ATOM   5913 O O   . ARG   B 2 66  ? 141.887 133.393 124.683 1.00 134.09 ? 89  ARG   P O   1 
ATOM   5914 C CB  . ARG   B 2 66  ? 140.723 130.505 125.112 1.00 145.03 ? 89  ARG   P CB  1 
ATOM   5915 C CG  . ARG   B 2 66  ? 142.040 130.351 124.364 1.00 147.05 ? 89  ARG   P CG  1 
ATOM   5916 C CD  . ARG   B 2 66  ? 142.288 128.893 124.001 1.00 151.86 ? 89  ARG   P CD  1 
ATOM   5917 N NE  . ARG   B 2 66  ? 142.235 128.018 125.170 1.00 153.76 ? 89  ARG   P NE  1 
ATOM   5918 C CZ  . ARG   B 2 66  ? 143.267 127.694 125.941 1.00 151.72 ? 89  ARG   P CZ  1 
ATOM   5919 N NH1 . ARG   B 2 66  ? 144.489 128.150 125.706 1.00 149.93 ? 89  ARG   P NH1 1 
ATOM   5920 N NH2 . ARG   B 2 66  ? 143.069 126.889 126.981 1.00 150.13 ? 89  ARG   P NH2 1 
ATOM   5921 N N   . PHE   B 2 67  ? 140.765 133.446 126.644 1.00 126.79 ? 90  PHE   P N   1 
ATOM   5922 C CA  . PHE   B 2 67  ? 141.498 134.574 127.206 1.00 122.71 ? 90  PHE   P CA  1 
ATOM   5923 C C   . PHE   B 2 67  ? 142.447 134.192 128.334 1.00 116.55 ? 90  PHE   P C   1 
ATOM   5924 O O   . PHE   B 2 67  ? 143.134 135.074 128.859 1.00 118.22 ? 90  PHE   P O   1 
ATOM   5925 C CB  . PHE   B 2 67  ? 140.519 135.631 127.725 1.00 122.01 ? 90  PHE   P CB  1 
ATOM   5926 C CG  . PHE   B 2 67  ? 139.592 136.174 126.678 1.00 125.63 ? 90  PHE   P CG  1 
ATOM   5927 C CD1 . PHE   B 2 67  ? 140.021 137.141 125.789 1.00 124.53 ? 90  PHE   P CD1 1 
ATOM   5928 C CD2 . PHE   B 2 67  ? 138.282 135.734 126.598 1.00 129.58 ? 90  PHE   P CD2 1 
ATOM   5929 C CE1 . PHE   B 2 67  ? 139.169 137.649 124.833 1.00 126.02 ? 90  PHE   P CE1 1 
ATOM   5930 C CE2 . PHE   B 2 67  ? 137.424 136.240 125.643 1.00 130.86 ? 90  PHE   P CE2 1 
ATOM   5931 C CZ  . PHE   B 2 67  ? 137.870 137.199 124.759 1.00 129.01 ? 90  PHE   P CZ  1 
ATOM   5932 N N   . TRP   B 2 68  ? 142.487 132.923 128.742 1.00 109.65 ? 91  TRP   P N   1 
ATOM   5933 C CA  . TRP   B 2 68  ? 143.334 132.405 129.817 1.00 103.70 ? 91  TRP   P CA  1 
ATOM   5934 C C   . TRP   B 2 68  ? 142.949 132.936 131.194 1.00 100.66 ? 91  TRP   P C   1 
ATOM   5935 O O   . TRP   B 2 68  ? 143.675 132.688 132.165 1.00 105.71 ? 91  TRP   P O   1 
ATOM   5936 C CB  . TRP   B 2 68  ? 144.825 132.696 129.579 1.00 111.43 ? 91  TRP   P CB  1 
ATOM   5937 C CG  . TRP   B 2 68  ? 145.425 132.050 128.363 1.00 122.95 ? 91  TRP   P CG  1 
ATOM   5938 C CD1 . TRP   B 2 68  ? 144.778 131.332 127.398 1.00 130.45 ? 91  TRP   P CD1 1 
ATOM   5939 C CD2 . TRP   B 2 68  ? 146.808 132.061 127.991 1.00 132.87 ? 91  TRP   P CD2 1 
ATOM   5940 N NE1 . TRP   B 2 68  ? 145.671 130.902 126.448 1.00 137.34 ? 91  TRP   P NE1 1 
ATOM   5941 C CE2 . TRP   B 2 68  ? 146.924 131.335 126.790 1.00 138.08 ? 91  TRP   P CE2 1 
ATOM   5942 C CE3 . TRP   B 2 68  ? 147.960 132.617 128.557 1.00 132.03 ? 91  TRP   P CE3 1 
ATOM   5943 C CZ2 . TRP   B 2 68  ? 148.145 131.152 126.144 1.00 137.74 ? 91  TRP   P CZ2 1 
ATOM   5944 C CZ3 . TRP   B 2 68  ? 149.171 132.433 127.914 1.00 132.29 ? 91  TRP   P CZ3 1 
ATOM   5945 C CH2 . TRP   B 2 68  ? 149.253 131.706 126.721 1.00 136.42 ? 91  TRP   P CH2 1 
ATOM   5946 N N   . GLU   B 2 69  ? 141.833 133.655 131.313 1.00 94.29  ? 92  GLU   P N   1 
ATOM   5947 C CA  . GLU   B 2 69  ? 141.346 134.221 132.566 1.00 88.00  ? 92  GLU   P CA  1 
ATOM   5948 C C   . GLU   B 2 69  ? 139.920 133.758 132.813 1.00 92.61  ? 92  GLU   P C   1 
ATOM   5949 O O   . GLU   B 2 69  ? 139.041 134.543 133.184 1.00 100.21 ? 92  GLU   P O   1 
ATOM   5950 C CB  . GLU   B 2 69  ? 141.434 135.746 132.537 1.00 90.07  ? 92  GLU   P CB  1 
ATOM   5951 C CG  . GLU   B 2 69  ? 141.249 136.460 133.880 1.00 87.74  ? 92  GLU   P CG  1 
ATOM   5952 C CD  . GLU   B 2 69  ? 142.395 136.236 134.836 1.00 92.96  ? 92  GLU   P CD  1 
ATOM   5953 O OE1 . GLU   B 2 69  ? 143.377 135.574 134.447 1.00 95.34  ? 92  GLU   P OE1 1 
ATOM   5954 O OE2 . GLU   B 2 69  ? 142.313 136.722 135.983 1.00 95.23  ? 92  GLU   P OE2 1 
ATOM   5955 N N   . SER   B 2 70  ? 139.661 132.476 132.575 1.00 88.66  ? 93  SER   P N   1 
ATOM   5956 C CA  . SER   B 2 70  ? 138.341 131.896 132.774 1.00 92.46  ? 93  SER   P CA  1 
ATOM   5957 C C   . SER   B 2 70  ? 138.495 130.496 133.342 1.00 105.87 ? 93  SER   P C   1 
ATOM   5958 O O   . SER   B 2 70  ? 139.162 129.649 132.742 1.00 112.96 ? 93  SER   P O   1 
ATOM   5959 C CB  . SER   B 2 70  ? 137.551 131.854 131.463 1.00 90.22  ? 93  SER   P CB  1 
ATOM   5960 O OG  . SER   B 2 70  ? 137.308 133.159 130.973 1.00 79.53  ? 93  SER   P OG  1 
ATOM   5961 N N   . TYR   B 2 71  ? 137.883 130.261 134.498 1.00 115.05 ? 94  TYR   P N   1 
ATOM   5962 C CA  . TYR   B 2 71  ? 137.922 128.940 135.107 1.00 127.22 ? 94  TYR   P CA  1 
ATOM   5963 C C   . TYR   B 2 71  ? 137.095 127.967 134.278 1.00 139.02 ? 94  TYR   P C   1 
ATOM   5964 O O   . TYR   B 2 71  ? 135.954 128.263 133.907 1.00 141.47 ? 94  TYR   P O   1 
ATOM   5965 C CB  . TYR   B 2 71  ? 137.416 129.003 136.552 1.00 135.03 ? 94  TYR   P CB  1 
ATOM   5966 C CG  . TYR   B 2 71  ? 136.343 127.999 136.913 1.00 147.90 ? 94  TYR   P CG  1 
ATOM   5967 C CD1 . TYR   B 2 71  ? 136.675 126.724 137.355 1.00 151.11 ? 94  TYR   P CD1 1 
ATOM   5968 C CD2 . TYR   B 2 71  ? 134.997 128.336 136.840 1.00 150.21 ? 94  TYR   P CD2 1 
ATOM   5969 C CE1 . TYR   B 2 71  ? 135.696 125.808 137.694 1.00 153.05 ? 94  TYR   P CE1 1 
ATOM   5970 C CE2 . TYR   B 2 71  ? 134.013 127.427 137.177 1.00 153.71 ? 94  TYR   P CE2 1 
ATOM   5971 C CZ  . TYR   B 2 71  ? 134.367 126.166 137.605 1.00 154.71 ? 94  TYR   P CZ  1 
ATOM   5972 O OH  . TYR   B 2 71  ? 133.389 125.259 137.942 1.00 154.29 ? 94  TYR   P OH  1 
ATOM   5973 N N   . ILE   B 2 72  ? 137.678 126.812 133.976 1.00 147.68 ? 95  ILE   P N   1 
ATOM   5974 C CA  . ILE   B 2 72  ? 137.040 125.801 133.139 1.00 153.60 ? 95  ILE   P CA  1 
ATOM   5975 C C   . ILE   B 2 72  ? 136.320 124.822 134.060 1.00 160.65 ? 95  ILE   P C   1 
ATOM   5976 O O   . ILE   B 2 72  ? 136.958 124.066 134.797 1.00 161.22 ? 95  ILE   P O   1 
ATOM   5977 C CB  . ILE   B 2 72  ? 138.058 125.079 132.248 1.00 151.70 ? 95  ILE   P CB  1 
ATOM   5978 C CG1 . ILE   B 2 72  ? 138.717 126.062 131.268 1.00 144.44 ? 95  ILE   P CG1 1 
ATOM   5979 C CG2 . ILE   B 2 72  ? 137.376 123.933 131.497 1.00 152.39 ? 95  ILE   P CG2 1 
ATOM   5980 C CD1 . ILE   B 2 72  ? 139.965 125.522 130.587 1.00 142.16 ? 95  ILE   P CD1 1 
ATOM   5981 N N   . TYR   B 2 73  ? 134.990 124.838 134.023 1.00 166.08 ? 96  TYR   P N   1 
ATOM   5982 C CA  . TYR   B 2 73  ? 134.214 123.921 134.846 1.00 168.38 ? 96  TYR   P CA  1 
ATOM   5983 C C   . TYR   B 2 73  ? 134.443 122.484 134.392 1.00 173.12 ? 96  TYR   P C   1 
ATOM   5984 O O   . TYR   B 2 73  ? 134.600 122.209 133.198 1.00 174.08 ? 96  TYR   P O   1 
ATOM   5985 C CB  . TYR   B 2 73  ? 132.724 124.271 134.783 1.00 168.65 ? 96  TYR   P CB  1 
ATOM   5986 C CG  . TYR   B 2 73  ? 131.931 123.467 133.776 1.00 172.46 ? 96  TYR   P CG  1 
ATOM   5987 C CD1 . TYR   B 2 73  ? 131.992 123.759 132.420 1.00 170.35 ? 96  TYR   P CD1 1 
ATOM   5988 C CD2 . TYR   B 2 73  ? 131.114 122.420 134.184 1.00 171.93 ? 96  TYR   P CD2 1 
ATOM   5989 C CE1 . TYR   B 2 73  ? 131.267 123.027 131.498 1.00 169.26 ? 96  TYR   P CE1 1 
ATOM   5990 C CE2 . TYR   B 2 73  ? 130.386 121.683 133.271 1.00 169.59 ? 96  TYR   P CE2 1 
ATOM   5991 C CZ  . TYR   B 2 73  ? 130.465 121.991 131.929 1.00 168.18 ? 96  TYR   P CZ  1 
ATOM   5992 O OH  . TYR   B 2 73  ? 129.741 121.260 131.016 1.00 163.33 ? 96  TYR   P OH  1 
ATOM   5993 N N   . ASN   B 2 74  ? 134.482 121.570 135.360 1.00 174.89 ? 97  ASN   P N   1 
ATOM   5994 C CA  . ASN   B 2 74  ? 134.685 120.146 135.119 1.00 176.32 ? 97  ASN   P CA  1 
ATOM   5995 C C   . ASN   B 2 74  ? 133.505 119.293 135.553 1.00 174.19 ? 97  ASN   P C   1 
ATOM   5996 O O   . ASN   B 2 74  ? 133.179 118.314 134.877 1.00 172.70 ? 97  ASN   P O   1 
ATOM   5997 C CB  . ASN   B 2 74  ? 135.948 119.667 135.848 1.00 175.69 ? 97  ASN   P CB  1 
ATOM   5998 C CG  . ASN   B 2 74  ? 136.260 118.210 135.575 1.00 175.10 ? 97  ASN   P CG  1 
ATOM   5999 O OD1 . ASN   B 2 74  ? 135.730 117.317 136.235 1.00 173.29 ? 97  ASN   P OD1 1 
ATOM   6000 N ND2 . ASN   B 2 74  ? 137.124 117.962 134.598 1.00 174.64 ? 97  ASN   P ND2 1 
ATOM   6001 N N   . GLY   B 2 75  ? 132.854 119.639 136.660 1.00 171.26 ? 98  GLY   P N   1 
ATOM   6002 C CA  . GLY   B 2 75  ? 131.718 118.881 137.154 1.00 166.30 ? 98  GLY   P CA  1 
ATOM   6003 C C   . GLY   B 2 75  ? 131.543 119.005 138.654 1.00 158.24 ? 98  GLY   P C   1 
ATOM   6004 O O   . GLY   B 2 75  ? 131.461 118.002 139.364 1.00 151.80 ? 98  GLY   P O   1 
HETATM 6005 C C1  . NAG   C 3 .   ? 159.493 119.121 93.969  1.00 86.09  ? 1   NAG   B C1  1 
HETATM 6006 C C2  . NAG   C 3 .   ? 160.514 117.984 94.083  1.00 87.42  ? 1   NAG   B C2  1 
HETATM 6007 C C3  . NAG   C 3 .   ? 161.136 117.987 95.472  1.00 89.43  ? 1   NAG   B C3  1 
HETATM 6008 C C4  . NAG   C 3 .   ? 161.736 119.356 95.746  1.00 88.59  ? 1   NAG   B C4  1 
HETATM 6009 C C5  . NAG   C 3 .   ? 160.646 120.413 95.583  1.00 86.48  ? 1   NAG   B C5  1 
HETATM 6010 C C6  . NAG   C 3 .   ? 161.153 121.813 95.833  1.00 89.48  ? 1   NAG   B C6  1 
HETATM 6011 C C7  . NAG   C 3 .   ? 160.109 115.977 92.705  1.00 94.07  ? 1   NAG   B C7  1 
HETATM 6012 C C8  . NAG   C 3 .   ? 159.355 114.670 92.656  1.00 94.81  ? 1   NAG   B C8  1 
HETATM 6013 N N2  . NAG   C 3 .   ? 159.905 116.710 93.816  1.00 89.76  ? 1   NAG   B N2  1 
HETATM 6014 O O3  . NAG   C 3 .   ? 162.099 116.969 95.520  1.00 95.52  ? 1   NAG   B O3  1 
HETATM 6015 O O4  . NAG   C 3 .   ? 162.250 119.341 97.057  1.00 92.92  ? 1   NAG   B O4  1 
HETATM 6016 O O5  . NAG   C 3 .   ? 160.109 120.346 94.277  1.00 87.22  ? 1   NAG   B O5  1 
HETATM 6017 O O6  . NAG   C 3 .   ? 161.907 121.826 97.022  1.00 91.69  ? 1   NAG   B O6  1 
HETATM 6018 O O7  . NAG   C 3 .   ? 160.840 116.319 91.788  1.00 93.84  ? 1   NAG   B O7  1 
HETATM 6019 C C1  . NAG   C 3 .   ? 163.490 119.260 97.784  1.00 97.58  ? 2   NAG   B C1  1 
HETATM 6020 C C2  . NAG   C 3 .   ? 164.153 119.687 99.097  1.00 95.32  ? 2   NAG   B C2  1 
HETATM 6021 C C3  . NAG   C 3 .   ? 165.563 119.118 99.165  1.00 96.85  ? 2   NAG   B C3  1 
HETATM 6022 C C4  . NAG   C 3 .   ? 165.529 117.614 98.938  1.00 101.83 ? 2   NAG   B C4  1 
HETATM 6023 C C5  . NAG   C 3 .   ? 164.806 117.314 97.623  1.00 103.54 ? 2   NAG   B C5  1 
HETATM 6024 C C6  . NAG   C 3 .   ? 164.714 115.836 97.313  1.00 103.73 ? 2   NAG   B C6  1 
HETATM 6025 C C7  . NAG   C 3 .   ? 163.612 121.834 100.207 1.00 99.88  ? 2   NAG   B C7  1 
HETATM 6026 C C8  . NAG   C 3 .   ? 163.796 123.329 100.106 1.00 95.41  ? 2   NAG   B C8  1 
HETATM 6027 N N2  . NAG   C 3 .   ? 164.188 121.120 99.219  1.00 99.69  ? 2   NAG   B N2  1 
HETATM 6028 O O3  . NAG   C 3 .   ? 166.096 119.448 100.418 1.00 98.19  ? 2   NAG   B O3  1 
HETATM 6029 O O4  . NAG   C 3 .   ? 166.864 117.165 98.912  1.00 103.34 ? 2   NAG   B O4  1 
HETATM 6030 O O5  . NAG   C 3 .   ? 163.503 117.858 97.674  1.00 104.08 ? 2   NAG   B O5  1 
HETATM 6031 O O6  . NAG   C 3 .   ? 163.887 115.629 96.194  1.00 104.63 ? 2   NAG   B O6  1 
HETATM 6032 O O7  . NAG   C 3 .   ? 162.982 121.338 101.129 1.00 98.50  ? 2   NAG   B O7  1 
HETATM 6033 C C1  . NAG   D 3 .   ? 134.459 125.045 94.840  1.00 100.09 ? 1   NAG   C C1  1 
HETATM 6034 C C2  . NAG   D 3 .   ? 132.993 125.235 94.493  1.00 95.17  ? 1   NAG   C C2  1 
HETATM 6035 C C3  . NAG   D 3 .   ? 132.436 126.475 95.182  1.00 96.22  ? 1   NAG   C C3  1 
HETATM 6036 C C4  . NAG   D 3 .   ? 133.298 127.697 94.898  1.00 94.33  ? 1   NAG   C C4  1 
HETATM 6037 C C5  . NAG   D 3 .   ? 134.781 127.416 95.138  1.00 100.04 ? 1   NAG   C C5  1 
HETATM 6038 C C6  . NAG   D 3 .   ? 135.130 127.258 96.600  1.00 99.45  ? 1   NAG   C C6  1 
HETATM 6039 C C7  . NAG   D 3 .   ? 132.770 124.255 92.257  1.00 96.29  ? 1   NAG   C C7  1 
HETATM 6040 C C8  . NAG   D 3 .   ? 132.574 124.529 90.796  1.00 97.86  ? 1   NAG   C C8  1 
HETATM 6041 N N2  . NAG   D 3 .   ? 132.809 125.326 93.054  1.00 91.78  ? 1   NAG   C N2  1 
HETATM 6042 O O3  . NAG   D 3 .   ? 132.352 126.244 96.584  1.00 98.25  ? 1   NAG   C O3  1 
HETATM 6043 O O4  . NAG   D 3 .   ? 133.116 128.103 93.547  1.00 94.69  ? 1   NAG   C O4  1 
HETATM 6044 O O5  . NAG   D 3 .   ? 135.192 126.208 94.480  1.00 105.30 ? 1   NAG   C O5  1 
HETATM 6045 O O6  . NAG   D 3 .   ? 136.372 126.589 96.770  1.00 99.17  ? 1   NAG   C O6  1 
HETATM 6046 O O7  . NAG   D 3 .   ? 132.885 123.115 92.695  1.00 96.26  ? 1   NAG   C O7  1 
HETATM 6047 C C1  . NAG   D 3 .   ? 132.701 129.477 93.443  1.00 113.89 ? 2   NAG   C C1  1 
HETATM 6048 C C2  . NAG   D 3 .   ? 133.107 130.945 93.537  1.00 113.71 ? 2   NAG   C C2  1 
HETATM 6049 C C3  . NAG   D 3 .   ? 131.883 131.842 93.395  1.00 113.52 ? 2   NAG   C C3  1 
HETATM 6050 C C4  . NAG   D 3 .   ? 131.114 131.496 92.128  1.00 114.57 ? 2   NAG   C C4  1 
HETATM 6051 C C5  . NAG   D 3 .   ? 130.794 130.006 92.099  1.00 116.39 ? 2   NAG   C C5  1 
HETATM 6052 C C6  . NAG   D 3 .   ? 130.130 129.569 90.815  1.00 115.72 ? 2   NAG   C C6  1 
HETATM 6053 C C7  . NAG   D 3 .   ? 135.047 131.676 94.850  1.00 116.11 ? 2   NAG   C C7  1 
HETATM 6054 C C8  . NAG   D 3 .   ? 135.727 131.906 93.534  1.00 114.86 ? 2   NAG   C C8  1 
HETATM 6055 N N2  . NAG   D 3 .   ? 133.794 131.215 94.789  1.00 114.90 ? 2   NAG   C N2  1 
HETATM 6056 O O3  . NAG   D 3 .   ? 132.297 133.202 93.357  1.00 115.53 ? 2   NAG   C O3  1 
HETATM 6057 O O4  . NAG   D 3 .   ? 129.900 132.237 92.077  1.00 114.76 ? 2   NAG   C O4  1 
HETATM 6058 O O5  . NAG   D 3 .   ? 132.006 129.248 92.220  1.00 117.26 ? 2   NAG   C O5  1 
HETATM 6059 O O6  . NAG   D 3 .   ? 129.112 130.479 90.424  1.00 116.90 ? 2   NAG   C O6  1 
HETATM 6060 O O7  . NAG   D 3 .   ? 135.607 131.896 95.919  1.00 115.44 ? 2   NAG   C O7  1 
HETATM 6061 C C1  . NAG   E 3 .   ? 133.043 116.880 106.559 1.00 85.77  ? 1   NAG   D C1  1 
HETATM 6062 C C2  . NAG   E 3 .   ? 133.552 116.793 108.000 1.00 84.86  ? 1   NAG   D C2  1 
HETATM 6063 C C3  . NAG   E 3 .   ? 132.986 115.548 108.675 1.00 89.35  ? 1   NAG   D C3  1 
HETATM 6064 C C4  . NAG   E 3 .   ? 131.472 115.546 108.558 1.00 87.76  ? 1   NAG   D C4  1 
HETATM 6065 C C5  . NAG   E 3 .   ? 131.100 115.659 107.082 1.00 90.27  ? 1   NAG   D C5  1 
HETATM 6066 C C6  . NAG   E 3 .   ? 129.609 115.635 106.842 1.00 96.50  ? 1   NAG   D C6  1 
HETATM 6067 C C7  . NAG   E 3 .   ? 135.786 115.892 107.463 1.00 88.03  ? 1   NAG   D C7  1 
HETATM 6068 C C8  . NAG   E 3 .   ? 137.262 116.105 107.690 1.00 85.58  ? 1   NAG   D C8  1 
HETATM 6069 N N2  . NAG   E 3 .   ? 134.988 116.790 108.065 1.00 84.91  ? 1   NAG   D N2  1 
HETATM 6070 O O3  . NAG   E 3 .   ? 133.413 115.548 110.011 1.00 99.90  ? 1   NAG   D O3  1 
HETATM 6071 O O4  . NAG   E 3 .   ? 131.009 114.342 109.117 1.00 96.02  ? 1   NAG   D O4  1 
HETATM 6072 O O5  . NAG   E 3 .   ? 131.639 116.855 106.556 1.00 91.34  ? 1   NAG   D O5  1 
HETATM 6073 O O6  . NAG   E 3 .   ? 129.080 114.400 107.264 1.00 99.51  ? 1   NAG   D O6  1 
HETATM 6074 O O7  . NAG   E 3 .   ? 135.371 114.968 106.779 1.00 90.86  ? 1   NAG   D O7  1 
HETATM 6075 C C1  . NAG   E 3 .   ? 130.520 113.693 110.305 1.00 100.55 ? 2   NAG   D C1  1 
HETATM 6076 C C2  . NAG   E 3 .   ? 129.800 112.352 110.164 1.00 97.23  ? 2   NAG   D C2  1 
HETATM 6077 C C3  . NAG   E 3 .   ? 129.845 111.620 111.498 1.00 98.85  ? 2   NAG   D C3  1 
HETATM 6078 C C4  . NAG   E 3 .   ? 131.286 111.503 111.974 1.00 102.33 ? 2   NAG   D C4  1 
HETATM 6079 C C5  . NAG   E 3 .   ? 131.917 112.897 112.018 1.00 103.04 ? 2   NAG   D C5  1 
HETATM 6080 C C6  . NAG   E 3 .   ? 133.361 112.906 112.467 1.00 104.92 ? 2   NAG   D C6  1 
HETATM 6081 C C7  . NAG   E 3 .   ? 127.687 111.842 108.866 1.00 106.75 ? 2   NAG   D C7  1 
HETATM 6082 C C8  . NAG   E 3 .   ? 128.286 110.622 108.202 1.00 103.69 ? 2   NAG   D C8  1 
HETATM 6083 N N2  . NAG   E 3 .   ? 128.436 112.562 109.738 1.00 100.35 ? 2   NAG   D N2  1 
HETATM 6084 O O3  . NAG   E 3 .   ? 129.242 110.366 111.326 1.00 104.26 ? 2   NAG   D O3  1 
HETATM 6085 O O4  . NAG   E 3 .   ? 131.258 110.902 113.247 1.00 105.34 ? 2   NAG   D O4  1 
HETATM 6086 O O5  . NAG   E 3 .   ? 131.841 113.480 110.735 1.00 105.60 ? 2   NAG   D O5  1 
HETATM 6087 O O6  . NAG   E 3 .   ? 133.854 114.224 112.450 1.00 106.88 ? 2   NAG   D O6  1 
HETATM 6088 O O7  . NAG   E 3 .   ? 126.535 112.157 108.611 1.00 107.12 ? 2   NAG   D O7  1 
HETATM 6089 C C11 . A1AVC F 4 .   ? 139.313 143.201 133.409 1.00 66.87  ? 801 A1AVC A C11 1 
HETATM 6090 C C12 . A1AVC F 4 .   ? 139.357 143.134 131.855 1.00 67.80  ? 801 A1AVC A C12 1 
HETATM 6091 C C13 . A1AVC F 4 .   ? 138.522 144.318 131.282 1.00 66.23  ? 801 A1AVC A C13 1 
HETATM 6092 C C14 . A1AVC F 4 .   ? 137.423 144.194 130.470 1.00 64.25  ? 801 A1AVC A C14 1 
HETATM 6093 C C15 . A1AVC F 4 .   ? 136.887 142.821 130.021 1.00 74.59  ? 801 A1AVC A C15 1 
HETATM 6094 C C16 . A1AVC F 4 .   ? 136.705 145.489 129.967 1.00 61.53  ? 801 A1AVC A C16 1 
HETATM 6095 C C01 . A1AVC F 4 .   ? 137.767 141.123 133.608 1.00 75.69  ? 801 A1AVC A C01 1 
HETATM 6096 C C02 . A1AVC F 4 .   ? 138.603 142.298 134.216 1.00 74.96  ? 801 A1AVC A C02 1 
HETATM 6097 C C03 . A1AVC F 4 .   ? 138.635 142.462 135.622 1.00 73.80  ? 801 A1AVC A C03 1 
HETATM 6098 C C04 . A1AVC F 4 .   ? 139.390 143.534 136.218 1.00 66.36  ? 801 A1AVC A C04 1 
HETATM 6099 C C05 . A1AVC F 4 .   ? 139.411 143.681 137.642 1.00 70.55  ? 801 A1AVC A C05 1 
HETATM 6100 C C06 . A1AVC F 4 .   ? 140.147 144.721 138.229 1.00 74.99  ? 801 A1AVC A C06 1 
HETATM 6101 C C07 . A1AVC F 4 .   ? 140.858 145.616 137.422 1.00 76.46  ? 801 A1AVC A C07 1 
HETATM 6102 C C08 . A1AVC F 4 .   ? 140.835 145.471 136.031 1.00 73.53  ? 801 A1AVC A C08 1 
HETATM 6103 C C09 . A1AVC F 4 .   ? 140.079 144.401 135.435 1.00 66.89  ? 801 A1AVC A C09 1 
HETATM 6104 C C10 . A1AVC F 4 .   ? 140.053 144.248 134.018 1.00 66.41  ? 801 A1AVC A C10 1 
HETATM 6105 C C17 . A1AVC F 4 .   ? 135.169 145.520 130.330 1.00 63.86  ? 801 A1AVC A C17 1 
HETATM 6106 C C18 . A1AVC F 4 .   ? 134.472 146.765 129.681 1.00 61.26  ? 801 A1AVC A C18 1 
HETATM 6107 C C19 . A1AVC F 4 .   ? 133.152 147.140 130.329 1.00 61.50  ? 801 A1AVC A C19 1 
HETATM 6108 C C20 . A1AVC F 4 .   ? 132.268 145.901 130.471 1.00 68.38  ? 801 A1AVC A C20 1 
HETATM 6109 C C21 . A1AVC F 4 .   ? 132.449 148.191 129.445 1.00 67.98  ? 801 A1AVC A C21 1 
HETATM 6110 C C22 . A1AVC F 4 .   ? 131.795 149.345 130.266 1.00 73.77  ? 801 A1AVC A C22 1 
HETATM 6111 C C23 . A1AVC F 4 .   ? 132.770 150.532 130.415 1.00 79.47  ? 801 A1AVC A C23 1 
HETATM 6112 C C24 . A1AVC F 4 .   ? 132.365 151.693 131.373 1.00 82.69  ? 801 A1AVC A C24 1 
HETATM 6113 C C25 . A1AVC F 4 .   ? 131.968 151.164 132.743 1.00 77.39  ? 801 A1AVC A C25 1 
HETATM 6114 C C26 . A1AVC F 4 .   ? 131.212 152.510 130.794 1.00 90.16  ? 801 A1AVC A C26 1 
HETATM 6115 C C27 . A1AVC F 4 .   ? 131.705 153.698 129.917 1.00 95.26  ? 801 A1AVC A C27 1 
HETATM 6116 C C28 . A1AVC F 4 .   ? 130.721 154.027 128.755 1.00 96.60  ? 801 A1AVC A C28 1 
HETATM 6117 C C29 . A1AVC F 4 .   ? 130.646 155.500 128.329 1.00 101.83 ? 801 A1AVC A C29 1 
HETATM 6118 C C30 . A1AVC F 4 .   ? 131.989 156.052 127.770 1.00 98.52  ? 801 A1AVC A C30 1 
HETATM 6119 C C31 . A1AVC F 4 .   ? 130.093 156.393 129.417 1.00 97.50  ? 801 A1AVC A C31 1 
HETATM 6120 O O32 . A1AVC F 4 .   ? 140.765 145.149 133.219 1.00 71.72  ? 801 A1AVC A O32 1 
HETATM 6121 O O33 . A1AVC F 4 .   ? 137.943 141.595 136.470 1.00 79.85  ? 801 A1AVC A O33 1 
HETATM 6122 C C22 . 6PL   G 5 .   ? 149.003 162.807 144.193 0.60 70.34  ? 802 6PL   A C22 1 
HETATM 6123 C C21 . 6PL   G 5 .   ? 149.271 161.860 143.029 0.60 74.89  ? 802 6PL   A C21 1 
HETATM 6124 C C20 . 6PL   G 5 .   ? 148.275 160.709 142.942 0.60 75.96  ? 802 6PL   A C20 1 
HETATM 6125 C C19 . 6PL   G 5 .   ? 148.330 159.767 144.139 0.60 75.14  ? 802 6PL   A C19 1 
HETATM 6126 C C18 . 6PL   G 5 .   ? 147.500 158.502 143.952 0.60 73.80  ? 802 6PL   A C18 1 
HETATM 6127 C C17 . 6PL   G 5 .   ? 147.540 157.578 145.163 0.60 72.70  ? 802 6PL   A C17 1 
HETATM 6128 C C16 . 6PL   G 5 .   ? 147.159 156.138 144.841 0.60 72.67  ? 802 6PL   A C16 1 
HETATM 6129 C C15 . 6PL   G 5 .   ? 147.008 155.263 146.080 0.60 72.69  ? 802 6PL   A C15 1 
HETATM 6130 C C14 . 6PL   G 5 .   ? 148.337 154.878 146.719 0.60 72.73  ? 802 6PL   A C14 1 
HETATM 6131 C C13 . 6PL   G 5 .   ? 148.219 154.496 148.190 0.60 69.26  ? 802 6PL   A C13 1 
HETATM 6132 C C12 . 6PL   G 5 .   ? 147.987 155.701 149.085 0.60 68.67  ? 802 6PL   A C12 1 
HETATM 6133 C C11 . 6PL   G 5 .   ? 148.207 155.416 150.541 0.60 67.53  ? 802 6PL   A C11 1 
HETATM 6134 O O11 . 6PL   G 5 .   ? 149.117 154.765 150.990 0.60 70.17  ? 802 6PL   A O11 1 
HETATM 6135 O O3  . 6PL   G 5 .   ? 147.266 155.961 151.297 0.60 66.33  ? 802 6PL   A O3  1 
HETATM 6136 C C3  . 6PL   G 5 .   ? 147.437 157.291 151.766 0.60 65.21  ? 802 6PL   A C3  1 
HETATM 6137 C C2  . 6PL   G 5 .   ? 147.575 157.261 153.274 0.60 64.16  ? 802 6PL   A C2  1 
HETATM 6138 C C1  . 6PL   G 5 .   ? 146.978 158.458 154.003 0.60 64.79  ? 802 6PL   A C1  1 
HETATM 6139 O O3P . 6PL   G 5 .   ? 145.571 158.383 153.957 0.60 62.01  ? 802 6PL   A O3P 1 
HETATM 6140 P P   . 6PL   G 5 .   ? 144.664 159.177 155.051 0.60 59.23  ? 802 6PL   A P   1 
HETATM 6141 O O1P . 6PL   G 5 .   ? 143.845 158.228 155.872 0.60 60.15  ? 802 6PL   A O1P 1 
HETATM 6142 O O2P . 6PL   G 5 .   ? 145.471 160.236 155.730 0.60 68.68  ? 802 6PL   A O2P 1 
HETATM 6143 O O4P . 6PL   G 5 .   ? 143.689 159.843 153.905 0.60 64.96  ? 802 6PL   A O4P 1 
HETATM 6144 C C4  . 6PL   G 5 .   ? 144.242 160.780 153.020 0.60 69.66  ? 802 6PL   A C4  1 
HETATM 6145 C C5  . 6PL   G 5 .   ? 143.451 160.905 151.738 0.60 69.13  ? 802 6PL   A C5  1 
HETATM 6146 N N   . 6PL   G 5 .   ? 141.961 161.164 151.788 0.60 65.30  ? 802 6PL   A N   1 
HETATM 6147 C C7  . 6PL   G 5 .   ? 141.509 161.815 153.048 0.60 65.01  ? 802 6PL   A C7  1 
HETATM 6148 C C8  . 6PL   G 5 .   ? 141.631 162.081 150.661 0.60 68.77  ? 802 6PL   A C8  1 
HETATM 6149 C C6  . 6PL   G 5 .   ? 141.175 159.913 151.582 0.60 68.21  ? 802 6PL   A C6  1 
HETATM 6150 O O2  . 6PL   G 5 .   ? 148.946 156.975 153.611 0.60 65.40  ? 802 6PL   A O2  1 
HETATM 6151 C C31 . 6PL   G 5 .   ? 149.931 157.868 153.537 0.60 72.13  ? 802 6PL   A C31 1 
HETATM 6152 O O31 . 6PL   G 5 .   ? 149.780 159.035 153.282 0.60 75.41  ? 802 6PL   A O31 1 
HETATM 6153 C C32 . 6PL   G 5 .   ? 151.261 157.216 153.800 0.60 75.30  ? 802 6PL   A C32 1 
HETATM 6154 C C33 . 6PL   G 5 .   ? 152.428 157.923 153.125 0.60 81.27  ? 802 6PL   A C33 1 
HETATM 6155 C C34 . 6PL   G 5 .   ? 153.441 156.955 152.522 0.60 84.97  ? 802 6PL   A C34 1 
HETATM 6156 C C35 . 6PL   G 5 .   ? 154.511 157.672 151.707 0.60 86.99  ? 802 6PL   A C35 1 
HETATM 6157 C C36 . 6PL   G 5 .   ? 155.394 156.738 150.886 0.60 89.36  ? 802 6PL   A C36 1 
HETATM 6158 C C37 . 6PL   G 5 .   ? 156.233 157.476 149.848 0.60 89.86  ? 802 6PL   A C37 1 
HETATM 6159 C C38 . 6PL   G 5 .   ? 157.402 158.265 150.429 0.60 91.45  ? 802 6PL   A C38 1 
HETATM 6160 C C39 . 6PL   G 5 .   ? 158.578 157.377 150.820 0.60 91.94  ? 802 6PL   A C39 1 
HETATM 6161 C C40 . 6PL   G 5 .   ? 159.828 158.149 151.226 0.60 90.84  ? 802 6PL   A C40 1 
HETATM 6162 C C41 . 6PL   G 5 .   ? 160.987 157.238 151.614 0.60 89.01  ? 802 6PL   A C41 1 
HETATM 6163 C C42 . 6PL   G 5 .   ? 162.281 157.978 151.932 0.60 88.37  ? 802 6PL   A C42 1 
HETATM 6164 C C43 . 6PL   G 5 .   ? 162.197 158.817 153.202 0.60 89.33  ? 802 6PL   A C43 1 
HETATM 6165 C C44 . 6PL   G 5 .   ? 163.525 159.434 153.626 0.60 89.28  ? 802 6PL   A C44 1 
HETATM 6166 C C45 . 6PL   G 5 .   ? 164.508 158.417 154.192 0.60 86.43  ? 802 6PL   A C45 1 
HETATM 6167 C C46 . 6PL   G 5 .   ? 165.699 159.054 154.895 0.60 84.55  ? 802 6PL   A C46 1 
HETATM 6168 C C26 . 6PL   H 5 .   ? 112.767 123.152 148.215 0.60 95.33  ? 803 6PL   A C26 1 
HETATM 6169 C C25 . 6PL   H 5 .   ? 114.074 122.539 147.729 0.60 95.84  ? 803 6PL   A C25 1 
HETATM 6170 C C24 . 6PL   H 5 .   ? 115.134 123.581 147.388 0.60 96.52  ? 803 6PL   A C24 1 
HETATM 6171 C C23 . 6PL   H 5 .   ? 115.642 124.353 148.600 0.60 96.59  ? 803 6PL   A C23 1 
HETATM 6172 C C22 . 6PL   H 5 .   ? 116.788 125.304 148.274 0.60 96.90  ? 803 6PL   A C22 1 
HETATM 6173 C C21 . 6PL   H 5 .   ? 117.250 126.121 149.475 0.60 95.94  ? 803 6PL   A C21 1 
HETATM 6174 C C20 . 6PL   H 5 .   ? 118.312 127.159 149.134 0.60 94.48  ? 803 6PL   A C20 1 
HETATM 6175 C C19 . 6PL   H 5 .   ? 119.660 126.552 148.761 0.60 95.39  ? 803 6PL   A C19 1 
HETATM 6176 C C18 . 6PL   H 5 .   ? 120.780 127.584 148.683 0.60 94.05  ? 803 6PL   A C18 1 
HETATM 6177 C C17 . 6PL   H 5 .   ? 122.088 127.019 148.142 0.60 91.39  ? 803 6PL   A C17 1 
HETATM 6178 C C16 . 6PL   H 5 .   ? 123.138 128.091 147.876 0.60 90.14  ? 803 6PL   A C16 1 
HETATM 6179 C C15 . 6PL   H 5 .   ? 124.509 127.523 147.538 0.60 86.52  ? 803 6PL   A C15 1 
HETATM 6180 C C14 . 6PL   H 5 .   ? 125.562 128.600 147.312 0.60 85.57  ? 803 6PL   A C14 1 
HETATM 6181 C C13 . 6PL   H 5 .   ? 125.531 129.183 145.904 0.60 85.58  ? 803 6PL   A C13 1 
HETATM 6182 C C12 . 6PL   H 5 .   ? 126.603 130.242 145.710 0.60 84.64  ? 803 6PL   A C12 1 
HETATM 6183 C C11 . 6PL   H 5 .   ? 126.892 130.561 144.271 0.60 84.23  ? 803 6PL   A C11 1 
HETATM 6184 O O11 . 6PL   H 5 .   ? 126.308 130.091 143.325 0.60 83.04  ? 803 6PL   A O11 1 
HETATM 6185 O O3  . 6PL   H 5 .   ? 127.889 131.432 144.161 0.60 81.33  ? 803 6PL   A O3  1 
HETATM 6186 C C3  . 6PL   H 5 .   ? 128.542 131.560 142.904 0.60 77.95  ? 803 6PL   A C3  1 
HETATM 6187 C C2  . 6PL   H 5 .   ? 127.766 132.487 141.990 0.60 77.43  ? 803 6PL   A C2  1 
HETATM 6188 C C1  . 6PL   H 5 .   ? 128.416 132.726 140.635 0.60 75.28  ? 803 6PL   A C1  1 
HETATM 6189 O O3P . 6PL   H 5 .   ? 128.328 131.565 139.837 0.60 75.44  ? 803 6PL   A O3P 1 
HETATM 6190 P P   . 6PL   H 5 .   ? 129.446 131.260 138.691 0.60 66.18  ? 803 6PL   A P   1 
HETATM 6191 O O1P . 6PL   H 5 .   ? 130.738 131.958 138.995 0.60 71.93  ? 803 6PL   A O1P 1 
HETATM 6192 O O2P . 6PL   H 5 .   ? 129.452 129.812 138.326 0.60 61.94  ? 803 6PL   A O2P 1 
HETATM 6193 O O4P . 6PL   H 5 .   ? 128.644 132.125 137.542 0.60 69.23  ? 803 6PL   A O4P 1 
HETATM 6194 C C4  . 6PL   H 5 .   ? 127.802 131.467 136.630 0.60 66.77  ? 803 6PL   A C4  1 
HETATM 6195 C C5  . 6PL   H 5 .   ? 127.355 132.363 135.494 0.60 64.80  ? 803 6PL   A C5  1 
HETATM 6196 N N   . 6PL   H 5 .   ? 128.373 133.213 134.765 0.60 63.09  ? 803 6PL   A N   1 
HETATM 6197 C C7  . 6PL   H 5 .   ? 129.600 132.443 134.424 0.60 65.08  ? 803 6PL   A C7  1 
HETATM 6198 C C8  . 6PL   H 5 .   ? 127.729 133.647 133.491 0.60 61.65  ? 803 6PL   A C8  1 
HETATM 6199 C C6  . 6PL   H 5 .   ? 128.757 134.444 135.520 0.60 64.72  ? 803 6PL   A C6  1 
HETATM 6200 O O2  . 6PL   H 5 .   ? 127.446 133.719 142.664 0.60 78.76  ? 803 6PL   A O2  1 
HETATM 6201 C C31 . 6PL   H 5 .   ? 128.268 134.310 143.530 0.60 80.12  ? 803 6PL   A C31 1 
HETATM 6202 O O31 . 6PL   H 5 .   ? 129.410 134.612 143.282 0.60 80.87  ? 803 6PL   A O31 1 
HETATM 6203 C C32 . 6PL   H 5 .   ? 127.570 134.536 144.845 0.60 79.49  ? 803 6PL   A C32 1 
HETATM 6204 C C33 . 6PL   H 5 .   ? 128.173 135.639 145.700 0.60 78.90  ? 803 6PL   A C33 1 
HETATM 6205 C C34 . 6PL   H 5 .   ? 127.333 135.917 146.943 0.60 78.95  ? 803 6PL   A C34 1 
HETATM 6206 C C35 . 6PL   H 5 .   ? 127.602 137.289 147.547 0.60 77.84  ? 803 6PL   A C35 1 
HETATM 6207 C C36 . 6PL   H 5 .   ? 128.967 137.423 148.211 0.60 77.87  ? 803 6PL   A C36 1 
HETATM 6208 C C37 . 6PL   H 5 .   ? 129.210 138.817 148.779 0.60 76.13  ? 803 6PL   A C37 1 
HETATM 6209 C C38 . 6PL   H 5 .   ? 129.588 139.859 147.732 0.60 74.00  ? 803 6PL   A C38 1 
HETATM 6210 C C39 . 6PL   H 5 .   ? 129.515 141.286 148.262 0.60 73.93  ? 803 6PL   A C39 1 
HETATM 6211 C C40 . 6PL   H 5 .   ? 129.764 142.347 147.198 0.60 73.28  ? 803 6PL   A C40 1 
HETATM 6212 C C41 . 6PL   H 5 .   ? 129.264 143.729 147.602 0.60 73.08  ? 803 6PL   A C41 1 
HETATM 6213 C C42 . 6PL   H 5 .   ? 130.023 144.347 148.770 0.60 71.19  ? 803 6PL   A C42 1 
HETATM 6214 C C43 . 6PL   H 5 .   ? 129.638 145.800 149.019 0.60 71.15  ? 803 6PL   A C43 1 
HETATM 6215 C C44 . 6PL   H 5 .   ? 130.067 146.329 150.383 0.60 74.12  ? 803 6PL   A C44 1 
HETATM 6216 C C45 . 6PL   H 5 .   ? 129.187 145.831 151.524 0.60 75.12  ? 803 6PL   A C45 1 
HETATM 6217 C C46 . 6PL   H 5 .   ? 129.498 146.486 152.863 0.60 68.74  ? 803 6PL   A C46 1 
HETATM 6218 C C1  . NAG   I 6 .   ? 153.609 95.217  123.118 1.00 105.44 ? 804 NAG   A C1  1 
HETATM 6219 C C2  . NAG   I 6 .   ? 154.280 94.481  124.262 1.00 105.73 ? 804 NAG   A C2  1 
HETATM 6220 C C3  . NAG   I 6 .   ? 153.352 94.423  125.475 1.00 105.52 ? 804 NAG   A C3  1 
HETATM 6221 C C4  . NAG   I 6 .   ? 151.887 94.549  125.066 1.00 107.53 ? 804 NAG   A C4  1 
HETATM 6222 C C5  . NAG   I 6 .   ? 151.627 95.812  124.243 1.00 107.78 ? 804 NAG   A C5  1 
HETATM 6223 C C6  . NAG   I 6 .   ? 151.101 96.960  125.072 1.00 105.43 ? 804 NAG   A C6  1 
HETATM 6224 C C7  . NAG   I 6 .   ? 155.857 92.874  123.286 1.00 105.29 ? 804 NAG   A C7  1 
HETATM 6225 C C8  . NAG   I 6 .   ? 156.104 91.438  122.935 1.00 101.99 ? 804 NAG   A C8  1 
HETATM 6226 N N2  . NAG   I 6 .   ? 154.679 93.143  123.859 1.00 106.56 ? 804 NAG   A N2  1 
HETATM 6227 O O3  . NAG   I 6 .   ? 153.693 95.467  126.381 1.00 102.92 ? 804 NAG   A O3  1 
HETATM 6228 O O4  . NAG   I 6 .   ? 151.496 93.410  124.308 1.00 104.61 ? 804 NAG   A O4  1 
HETATM 6229 O O5  . NAG   I 6 .   ? 152.838 96.269  123.627 1.00 108.23 ? 804 NAG   A O5  1 
HETATM 6230 O O6  . NAG   I 6 .   ? 151.810 97.083  126.298 1.00 104.19 ? 804 NAG   A O6  1 
HETATM 6231 O O7  . NAG   I 6 .   ? 156.686 93.751  123.061 1.00 102.90 ? 804 NAG   A O7  1 
# 
