data_9BVM
# 
_entry.id   9BVM 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BVM         pdb_00009bvm 10.2210/pdb9bvm/pdb 
WWPDB D_1000284195 ?            ?                   
EMDB  EMD-44937    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-01-22 ? 
2 'Structure model' 1 1 2025-03-12 ? 
3 'Structure model' 1 2 2025-03-19 ? 
4 'Structure model' 1 3 2025-03-26 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
3 3 'Structure model' 'Data collection'     
4 4 'Structure model' 'Data collection'     
5 4 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
4 3 'Structure model' em_admin        
5 4 'Structure model' citation        
6 4 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_ASTM'         
4  2 'Structure model' '_citation.journal_id_CSD'          
5  2 'Structure model' '_citation.journal_id_ISSN'         
6  2 'Structure model' '_citation.pdbx_database_id_DOI'    
7  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
8  2 'Structure model' '_citation.title'                   
9  2 'Structure model' '_citation.year'                    
10 2 'Structure model' '_em_admin.last_update'             
11 3 'Structure model' '_em_admin.last_update'             
12 4 'Structure model' '_citation.journal_volume'          
13 4 'Structure model' '_citation.page_first'              
14 4 'Structure model' '_citation.page_last'               
15 4 'Structure model' '_citation.title'                   
16 4 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BVM 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
'Vitamin K-dependent gamma-carboxylase with protein C propeptide and glutamate-rich region and with vitamin K hydroquinone' 
_pdbx_database_related.db_id          EMD-44937 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              weikai@wustl.edu 
_pdbx_contact_author.name_first         Weikai 
_pdbx_contact_author.name_last          Li 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-8711-1904 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Li, W.'  1 0000-0002-8711-1904 
'Liu, B.' 2 0000-0002-6581-780X 
'Cao, Q.' 3 0000-0003-2517-2231 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Nature 
_citation.journal_id_ASTM           NATUAS 
_citation.journal_id_CSD            0006 
_citation.journal_id_ISSN           1476-4687 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            639 
_citation.language                  ? 
_citation.page_first                816 
_citation.page_last                 824 
_citation.title                     'Molecular basis of vitamin-K-driven gamma-carboxylation at the membrane interface.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41586-025-08648-1 
_citation.pdbx_database_id_PubMed   39880037 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Cao, Q.'      1  0000-0003-2517-2231 
primary 'Ammerman, A.' 2  0000-0001-9245-4015 
primary 'Saimi, M.'    3  ?                   
primary 'Lin, Z.'      4  ?                   
primary 'Shen, G.'     5  0000-0002-5006-2790 
primary 'Chen, H.'     6  0000-0002-9835-5138 
primary 'Sun, J.'      7  0000-0001-8775-5032 
primary 'Chai, M.'     8  ?                   
primary 'Liu, S.'      9  ?                   
primary 'Hsu, F.F.'    10 ?                   
primary 'Krezel, A.M.' 11 ?                   
primary 'Gross, M.L.'  12 0000-0003-1159-4636 
primary 'Xu, J.'       13 0000-0002-2120-8287 
primary 'Garcia, B.A.' 14 0000-0003-3596-4750 
primary 'Liu, B.'      15 0000-0002-6581-780X 
primary 'Li, W.'       16 0000-0002-8711-1904 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Vitamin K-dependent gamma-carboxylase' 85005.680 1 4.1.1.90 ? ? ? 
2 polymer     man 'Activation peptide' 8219.110  1 ?        ? ? ? 
3 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401   3 ?        ? 
? ? 
4 non-polymer syn 'vitamin K1 hydroquinone' 452.712   1 ?        ? ? ? 
5 non-polymer syn 
'(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE' 763.100   2 ? 
? ? ? 
6 non-polymer man 2-acetamido-2-deoxy-beta-D-glucopyranose 221.208   1 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Gamma-glutamyl carboxylase,Peptidyl-glutamate 4-carboxylase,Vitamin K gamma glutamyl carboxylase' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;GPRQDSRIGKLLGFEWTDLSSWRRLVTLLNRPTDPASLAVFRFLFGFLMVLDIPQERGLSSLDRKYLDGLDVCRFPLLDA
LRPLPLDWMYLVYTIMFLGALGMMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGLL
NAHRRNAHVPLWNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKLLLSEELTSLLVVHWGGLLLDLSA
GFLLFFDVSRSIGLFFVSYFHCMNSQLFSIGMFSYVMLASSPLFCSPEWPRKLVSYCPRRLQQLLPLKAAPQPSVSCVYK
RSRGKSGQKPGLRHQLGAAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGYL
NPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAAWSPFQRTSWVQPLL
MDLSPWRAKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGEY
HKVYTTSPSPSCYMYVYVNTTELALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQRL
QEIERRRNTPFHERFFRFLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGELNPSNTDSSHSNP
PESNPDPVHSEF
;
;GPRQDSRIGKLLGFEWTDLSSWRRLVTLLNRPTDPASLAVFRFLFGFLMVLDIPQERGLSSLDRKYLDGLDVCRFPLLDA
LRPLPLDWMYLVYTIMFLGALGMMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGLL
NAHRRNAHVPLWNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKLLLSEELTSLLVVHWGGLLLDLSA
GFLLFFDVSRSIGLFFVSYFHCMNSQLFSIGMFSYVMLASSPLFCSPEWPRKLVSYCPRRLQQLLPLKAAPQPSVSCVYK
RSRGKSGQKPGLRHQLGAAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGYL
NPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAAWSPFQRTSWVQPLL
MDLSPWRAKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGEY
HKVYTTSPSPSCYMYVYVNTTELALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQRL
QEIERRRNTPFHERFFRFLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGELNPSNTDSSHSNP
PESNPDPVHSEF
;
A ? 
2 'polypeptide(L)' no no TPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVD 
TPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVD P ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 'vitamin K1 hydroquinone'                                                                                            A1AVC 
5 '(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE' 6PL   
6 2-acetamido-2-deoxy-beta-D-glucopyranose                                                                             NAG   
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   ARG n 
1 4   GLN n 
1 5   ASP n 
1 6   SER n 
1 7   ARG n 
1 8   ILE n 
1 9   GLY n 
1 10  LYS n 
1 11  LEU n 
1 12  LEU n 
1 13  GLY n 
1 14  PHE n 
1 15  GLU n 
1 16  TRP n 
1 17  THR n 
1 18  ASP n 
1 19  LEU n 
1 20  SER n 
1 21  SER n 
1 22  TRP n 
1 23  ARG n 
1 24  ARG n 
1 25  LEU n 
1 26  VAL n 
1 27  THR n 
1 28  LEU n 
1 29  LEU n 
1 30  ASN n 
1 31  ARG n 
1 32  PRO n 
1 33  THR n 
1 34  ASP n 
1 35  PRO n 
1 36  ALA n 
1 37  SER n 
1 38  LEU n 
1 39  ALA n 
1 40  VAL n 
1 41  PHE n 
1 42  ARG n 
1 43  PHE n 
1 44  LEU n 
1 45  PHE n 
1 46  GLY n 
1 47  PHE n 
1 48  LEU n 
1 49  MET n 
1 50  VAL n 
1 51  LEU n 
1 52  ASP n 
1 53  ILE n 
1 54  PRO n 
1 55  GLN n 
1 56  GLU n 
1 57  ARG n 
1 58  GLY n 
1 59  LEU n 
1 60  SER n 
1 61  SER n 
1 62  LEU n 
1 63  ASP n 
1 64  ARG n 
1 65  LYS n 
1 66  TYR n 
1 67  LEU n 
1 68  ASP n 
1 69  GLY n 
1 70  LEU n 
1 71  ASP n 
1 72  VAL n 
1 73  CYS n 
1 74  ARG n 
1 75  PHE n 
1 76  PRO n 
1 77  LEU n 
1 78  LEU n 
1 79  ASP n 
1 80  ALA n 
1 81  LEU n 
1 82  ARG n 
1 83  PRO n 
1 84  LEU n 
1 85  PRO n 
1 86  LEU n 
1 87  ASP n 
1 88  TRP n 
1 89  MET n 
1 90  TYR n 
1 91  LEU n 
1 92  VAL n 
1 93  TYR n 
1 94  THR n 
1 95  ILE n 
1 96  MET n 
1 97  PHE n 
1 98  LEU n 
1 99  GLY n 
1 100 ALA n 
1 101 LEU n 
1 102 GLY n 
1 103 MET n 
1 104 MET n 
1 105 LEU n 
1 106 GLY n 
1 107 LEU n 
1 108 CYS n 
1 109 TYR n 
1 110 ARG n 
1 111 ILE n 
1 112 SER n 
1 113 CYS n 
1 114 VAL n 
1 115 LEU n 
1 116 PHE n 
1 117 LEU n 
1 118 LEU n 
1 119 PRO n 
1 120 TYR n 
1 121 TRP n 
1 122 TYR n 
1 123 VAL n 
1 124 PHE n 
1 125 LEU n 
1 126 LEU n 
1 127 ASP n 
1 128 LYS n 
1 129 THR n 
1 130 SER n 
1 131 TRP n 
1 132 ASN n 
1 133 ASN n 
1 134 HIS n 
1 135 SER n 
1 136 TYR n 
1 137 LEU n 
1 138 TYR n 
1 139 GLY n 
1 140 LEU n 
1 141 LEU n 
1 142 ALA n 
1 143 PHE n 
1 144 GLN n 
1 145 LEU n 
1 146 THR n 
1 147 PHE n 
1 148 MET n 
1 149 ASP n 
1 150 ALA n 
1 151 ASN n 
1 152 HIS n 
1 153 TYR n 
1 154 TRP n 
1 155 SER n 
1 156 VAL n 
1 157 ASP n 
1 158 GLY n 
1 159 LEU n 
1 160 LEU n 
1 161 ASN n 
1 162 ALA n 
1 163 HIS n 
1 164 ARG n 
1 165 ARG n 
1 166 ASN n 
1 167 ALA n 
1 168 HIS n 
1 169 VAL n 
1 170 PRO n 
1 171 LEU n 
1 172 TRP n 
1 173 ASN n 
1 174 TYR n 
1 175 ALA n 
1 176 VAL n 
1 177 LEU n 
1 178 ARG n 
1 179 GLY n 
1 180 GLN n 
1 181 ILE n 
1 182 PHE n 
1 183 ILE n 
1 184 VAL n 
1 185 TYR n 
1 186 PHE n 
1 187 ILE n 
1 188 ALA n 
1 189 GLY n 
1 190 VAL n 
1 191 LYS n 
1 192 LYS n 
1 193 LEU n 
1 194 ASP n 
1 195 ALA n 
1 196 ASP n 
1 197 TRP n 
1 198 VAL n 
1 199 GLU n 
1 200 GLY n 
1 201 TYR n 
1 202 SER n 
1 203 MET n 
1 204 GLU n 
1 205 TYR n 
1 206 LEU n 
1 207 SER n 
1 208 ARG n 
1 209 HIS n 
1 210 TRP n 
1 211 LEU n 
1 212 PHE n 
1 213 SER n 
1 214 PRO n 
1 215 PHE n 
1 216 LYS n 
1 217 LEU n 
1 218 LEU n 
1 219 LEU n 
1 220 SER n 
1 221 GLU n 
1 222 GLU n 
1 223 LEU n 
1 224 THR n 
1 225 SER n 
1 226 LEU n 
1 227 LEU n 
1 228 VAL n 
1 229 VAL n 
1 230 HIS n 
1 231 TRP n 
1 232 GLY n 
1 233 GLY n 
1 234 LEU n 
1 235 LEU n 
1 236 LEU n 
1 237 ASP n 
1 238 LEU n 
1 239 SER n 
1 240 ALA n 
1 241 GLY n 
1 242 PHE n 
1 243 LEU n 
1 244 LEU n 
1 245 PHE n 
1 246 PHE n 
1 247 ASP n 
1 248 VAL n 
1 249 SER n 
1 250 ARG n 
1 251 SER n 
1 252 ILE n 
1 253 GLY n 
1 254 LEU n 
1 255 PHE n 
1 256 PHE n 
1 257 VAL n 
1 258 SER n 
1 259 TYR n 
1 260 PHE n 
1 261 HIS n 
1 262 CYS n 
1 263 MET n 
1 264 ASN n 
1 265 SER n 
1 266 GLN n 
1 267 LEU n 
1 268 PHE n 
1 269 SER n 
1 270 ILE n 
1 271 GLY n 
1 272 MET n 
1 273 PHE n 
1 274 SER n 
1 275 TYR n 
1 276 VAL n 
1 277 MET n 
1 278 LEU n 
1 279 ALA n 
1 280 SER n 
1 281 SER n 
1 282 PRO n 
1 283 LEU n 
1 284 PHE n 
1 285 CYS n 
1 286 SER n 
1 287 PRO n 
1 288 GLU n 
1 289 TRP n 
1 290 PRO n 
1 291 ARG n 
1 292 LYS n 
1 293 LEU n 
1 294 VAL n 
1 295 SER n 
1 296 TYR n 
1 297 CYS n 
1 298 PRO n 
1 299 ARG n 
1 300 ARG n 
1 301 LEU n 
1 302 GLN n 
1 303 GLN n 
1 304 LEU n 
1 305 LEU n 
1 306 PRO n 
1 307 LEU n 
1 308 LYS n 
1 309 ALA n 
1 310 ALA n 
1 311 PRO n 
1 312 GLN n 
1 313 PRO n 
1 314 SER n 
1 315 VAL n 
1 316 SER n 
1 317 CYS n 
1 318 VAL n 
1 319 TYR n 
1 320 LYS n 
1 321 ARG n 
1 322 SER n 
1 323 ARG n 
1 324 GLY n 
1 325 LYS n 
1 326 SER n 
1 327 GLY n 
1 328 GLN n 
1 329 LYS n 
1 330 PRO n 
1 331 GLY n 
1 332 LEU n 
1 333 ARG n 
1 334 HIS n 
1 335 GLN n 
1 336 LEU n 
1 337 GLY n 
1 338 ALA n 
1 339 ALA n 
1 340 PHE n 
1 341 THR n 
1 342 LEU n 
1 343 LEU n 
1 344 TYR n 
1 345 LEU n 
1 346 LEU n 
1 347 GLU n 
1 348 GLN n 
1 349 LEU n 
1 350 PHE n 
1 351 LEU n 
1 352 PRO n 
1 353 TYR n 
1 354 SER n 
1 355 HIS n 
1 356 PHE n 
1 357 LEU n 
1 358 THR n 
1 359 GLN n 
1 360 GLY n 
1 361 TYR n 
1 362 ASN n 
1 363 ASN n 
1 364 TRP n 
1 365 THR n 
1 366 ASN n 
1 367 GLY n 
1 368 LEU n 
1 369 TYR n 
1 370 GLY n 
1 371 TYR n 
1 372 SER n 
1 373 TRP n 
1 374 ASP n 
1 375 MET n 
1 376 MET n 
1 377 VAL n 
1 378 HIS n 
1 379 SER n 
1 380 ARG n 
1 381 SER n 
1 382 HIS n 
1 383 GLN n 
1 384 HIS n 
1 385 VAL n 
1 386 LYS n 
1 387 ILE n 
1 388 THR n 
1 389 TYR n 
1 390 ARG n 
1 391 ASP n 
1 392 GLY n 
1 393 ARG n 
1 394 THR n 
1 395 GLY n 
1 396 GLU n 
1 397 LEU n 
1 398 GLY n 
1 399 TYR n 
1 400 LEU n 
1 401 ASN n 
1 402 PRO n 
1 403 GLY n 
1 404 VAL n 
1 405 PHE n 
1 406 THR n 
1 407 GLN n 
1 408 SER n 
1 409 ARG n 
1 410 ARG n 
1 411 TRP n 
1 412 LYS n 
1 413 ASP n 
1 414 HIS n 
1 415 ALA n 
1 416 ASP n 
1 417 MET n 
1 418 LEU n 
1 419 LYS n 
1 420 GLN n 
1 421 TYR n 
1 422 ALA n 
1 423 THR n 
1 424 CYS n 
1 425 LEU n 
1 426 SER n 
1 427 ARG n 
1 428 LEU n 
1 429 LEU n 
1 430 PRO n 
1 431 LYS n 
1 432 TYR n 
1 433 ASN n 
1 434 VAL n 
1 435 THR n 
1 436 GLU n 
1 437 PRO n 
1 438 GLN n 
1 439 ILE n 
1 440 TYR n 
1 441 PHE n 
1 442 ASP n 
1 443 ILE n 
1 444 TRP n 
1 445 VAL n 
1 446 SER n 
1 447 ILE n 
1 448 ASN n 
1 449 ASP n 
1 450 ARG n 
1 451 PHE n 
1 452 GLN n 
1 453 GLN n 
1 454 ARG n 
1 455 ILE n 
1 456 PHE n 
1 457 ASP n 
1 458 PRO n 
1 459 ARG n 
1 460 VAL n 
1 461 ASP n 
1 462 ILE n 
1 463 VAL n 
1 464 GLN n 
1 465 ALA n 
1 466 ALA n 
1 467 TRP n 
1 468 SER n 
1 469 PRO n 
1 470 PHE n 
1 471 GLN n 
1 472 ARG n 
1 473 THR n 
1 474 SER n 
1 475 TRP n 
1 476 VAL n 
1 477 GLN n 
1 478 PRO n 
1 479 LEU n 
1 480 LEU n 
1 481 MET n 
1 482 ASP n 
1 483 LEU n 
1 484 SER n 
1 485 PRO n 
1 486 TRP n 
1 487 ARG n 
1 488 ALA n 
1 489 LYS n 
1 490 LEU n 
1 491 GLN n 
1 492 GLU n 
1 493 ILE n 
1 494 LYS n 
1 495 SER n 
1 496 SER n 
1 497 LEU n 
1 498 ASP n 
1 499 ASN n 
1 500 HIS n 
1 501 THR n 
1 502 GLU n 
1 503 VAL n 
1 504 VAL n 
1 505 PHE n 
1 506 ILE n 
1 507 ALA n 
1 508 ASP n 
1 509 PHE n 
1 510 PRO n 
1 511 GLY n 
1 512 LEU n 
1 513 HIS n 
1 514 LEU n 
1 515 GLU n 
1 516 ASN n 
1 517 PHE n 
1 518 VAL n 
1 519 SER n 
1 520 GLU n 
1 521 ASP n 
1 522 LEU n 
1 523 GLY n 
1 524 ASN n 
1 525 THR n 
1 526 SER n 
1 527 ILE n 
1 528 GLN n 
1 529 LEU n 
1 530 LEU n 
1 531 GLN n 
1 532 GLY n 
1 533 GLU n 
1 534 VAL n 
1 535 THR n 
1 536 VAL n 
1 537 GLU n 
1 538 LEU n 
1 539 VAL n 
1 540 ALA n 
1 541 GLU n 
1 542 GLN n 
1 543 LYS n 
1 544 ASN n 
1 545 GLN n 
1 546 THR n 
1 547 LEU n 
1 548 ARG n 
1 549 GLU n 
1 550 GLY n 
1 551 GLU n 
1 552 LYS n 
1 553 MET n 
1 554 GLN n 
1 555 LEU n 
1 556 PRO n 
1 557 ALA n 
1 558 GLY n 
1 559 GLU n 
1 560 TYR n 
1 561 HIS n 
1 562 LYS n 
1 563 VAL n 
1 564 TYR n 
1 565 THR n 
1 566 THR n 
1 567 SER n 
1 568 PRO n 
1 569 SER n 
1 570 PRO n 
1 571 SER n 
1 572 CYS n 
1 573 TYR n 
1 574 MET n 
1 575 TYR n 
1 576 VAL n 
1 577 TYR n 
1 578 VAL n 
1 579 ASN n 
1 580 THR n 
1 581 THR n 
1 582 GLU n 
1 583 LEU n 
1 584 ALA n 
1 585 LEU n 
1 586 GLU n 
1 587 GLN n 
1 588 ASP n 
1 589 LEU n 
1 590 ALA n 
1 591 TYR n 
1 592 LEU n 
1 593 GLN n 
1 594 GLU n 
1 595 LEU n 
1 596 LYS n 
1 597 GLU n 
1 598 LYS n 
1 599 VAL n 
1 600 GLU n 
1 601 ASN n 
1 602 GLY n 
1 603 SER n 
1 604 GLU n 
1 605 THR n 
1 606 GLY n 
1 607 PRO n 
1 608 LEU n 
1 609 PRO n 
1 610 PRO n 
1 611 GLU n 
1 612 LEU n 
1 613 GLN n 
1 614 PRO n 
1 615 LEU n 
1 616 LEU n 
1 617 GLU n 
1 618 GLY n 
1 619 GLU n 
1 620 VAL n 
1 621 LYS n 
1 622 GLY n 
1 623 GLY n 
1 624 PRO n 
1 625 GLU n 
1 626 PRO n 
1 627 THR n 
1 628 PRO n 
1 629 LEU n 
1 630 VAL n 
1 631 GLN n 
1 632 THR n 
1 633 PHE n 
1 634 LEU n 
1 635 ARG n 
1 636 ARG n 
1 637 GLN n 
1 638 GLN n 
1 639 ARG n 
1 640 LEU n 
1 641 GLN n 
1 642 GLU n 
1 643 ILE n 
1 644 GLU n 
1 645 ARG n 
1 646 ARG n 
1 647 ARG n 
1 648 ASN n 
1 649 THR n 
1 650 PRO n 
1 651 PHE n 
1 652 HIS n 
1 653 GLU n 
1 654 ARG n 
1 655 PHE n 
1 656 PHE n 
1 657 ARG n 
1 658 PHE n 
1 659 LEU n 
1 660 LEU n 
1 661 ARG n 
1 662 LYS n 
1 663 LEU n 
1 664 TYR n 
1 665 VAL n 
1 666 PHE n 
1 667 ARG n 
1 668 ARG n 
1 669 SER n 
1 670 PHE n 
1 671 LEU n 
1 672 MET n 
1 673 THR n 
1 674 CYS n 
1 675 ILE n 
1 676 SER n 
1 677 LEU n 
1 678 ARG n 
1 679 ASN n 
1 680 LEU n 
1 681 ILE n 
1 682 LEU n 
1 683 GLY n 
1 684 ARG n 
1 685 PRO n 
1 686 SER n 
1 687 LEU n 
1 688 GLU n 
1 689 GLN n 
1 690 LEU n 
1 691 ALA n 
1 692 GLN n 
1 693 GLU n 
1 694 VAL n 
1 695 THR n 
1 696 TYR n 
1 697 ALA n 
1 698 ASN n 
1 699 LEU n 
1 700 ARG n 
1 701 PRO n 
1 702 PHE n 
1 703 GLU n 
1 704 ALA n 
1 705 VAL n 
1 706 GLY n 
1 707 GLU n 
1 708 LEU n 
1 709 ASN n 
1 710 PRO n 
1 711 SER n 
1 712 ASN n 
1 713 THR n 
1 714 ASP n 
1 715 SER n 
1 716 SER n 
1 717 HIS n 
1 718 SER n 
1 719 ASN n 
1 720 PRO n 
1 721 PRO n 
1 722 GLU n 
1 723 SER n 
1 724 ASN n 
1 725 PRO n 
1 726 ASP n 
1 727 PRO n 
1 728 VAL n 
1 729 HIS n 
1 730 SER n 
1 731 GLU n 
1 732 PHE n 
2 1   THR n 
2 2   PRO n 
2 3   ALA n 
2 4   PRO n 
2 5   LEU n 
2 6   ASP n 
2 7   SER n 
2 8   VAL n 
2 9   PHE n 
2 10  SER n 
2 11  SER n 
2 12  SER n 
2 13  GLU n 
2 14  ARG n 
2 15  ALA n 
2 16  HIS n 
2 17  GLN n 
2 18  VAL n 
2 19  LEU n 
2 20  ARG n 
2 21  ILE n 
2 22  ARG n 
2 23  LYS n 
2 24  ARG n 
2 25  ALA n 
2 26  ASN n 
2 27  SER n 
2 28  PHE n 
2 29  LEU n 
2 30  GLU n 
2 31  GLU n 
2 32  LEU n 
2 33  ARG n 
2 34  HIS n 
2 35  SER n 
2 36  SER n 
2 37  LEU n 
2 38  GLU n 
2 39  ARG n 
2 40  GLU n 
2 41  CYS n 
2 42  ILE n 
2 43  GLU n 
2 44  GLU n 
2 45  ILE n 
2 46  CYS n 
2 47  ASP n 
2 48  PHE n 
2 49  GLU n 
2 50  GLU n 
2 51  ALA n 
2 52  LYS n 
2 53  GLU n 
2 54  ILE n 
2 55  PHE n 
2 56  GLN n 
2 57  ASN n 
2 58  VAL n 
2 59  ASP n 
2 60  ASP n 
2 61  THR n 
2 62  LEU n 
2 63  ALA n 
2 64  PHE n 
2 65  TRP n 
2 66  SER n 
2 67  LYS n 
2 68  HIS n 
2 69  VAL n 
2 70  ASP n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 732 human ? 'GGCX, GC' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? 
? ? ? ? ? ? HEK293S ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 70  human ? PROC       ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? 
? ? ? ? ? ? HEK293S ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_branch.entity_id   3 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 3 DGlcpNAcb1-4DGlcpNAcb1-ROH                            'Glycam Condensed Sequence' GMML       1.0   
2 3 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1' WURCS                       PDB2Glycan 1.1.0 
3 3 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}'       LINUCS                      PDB-CARE   ?     
# 
_pdbx_entity_branch_link.link_id                    1 
_pdbx_entity_branch_link.entity_id                  3 
_pdbx_entity_branch_link.entity_branch_list_num_1   2 
_pdbx_entity_branch_link.comp_id_1                  NAG 
_pdbx_entity_branch_link.atom_id_1                  C1 
_pdbx_entity_branch_link.leaving_atom_id_1          O1 
_pdbx_entity_branch_link.entity_branch_list_num_2   1 
_pdbx_entity_branch_link.comp_id_2                  NAG 
_pdbx_entity_branch_link.atom_id_2                  O4 
_pdbx_entity_branch_link.leaving_atom_id_2          HO4 
_pdbx_entity_branch_link.value_order                sing 
_pdbx_entity_branch_link.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
6PL   non-polymer                  . 
'(4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE' 
1-PALMITOYL-2-STEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE 'C42 H85 N O8 P 1' 763.100 
A1AVC non-polymer                  . 'vitamin K1 hydroquinone' 
'2-methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]naphthalene-1,4-diol' 'C31 H48 O2'       452.712 
ALA   'L-peptide linking'          y ALANINE ? 'C3 H7 N O2'       89.093  
ARG   'L-peptide linking'          y ARGININE ? 'C6 H15 N4 O2 1'   175.209 
ASN   'L-peptide linking'          y ASPARAGINE ? 'C4 H8 N2 O3'      132.118 
ASP   'L-peptide linking'          y 'ASPARTIC ACID' ? 'C4 H7 N O4'       133.103 
CYS   'L-peptide linking'          y CYSTEINE ? 'C3 H7 N O2 S'     121.158 
GLN   'L-peptide linking'          y GLUTAMINE ? 'C5 H10 N2 O3'     146.144 
GLU   'L-peptide linking'          y 'GLUTAMIC ACID' ? 'C5 H9 N O4'       147.129 
GLY   'peptide linking'            y GLYCINE ? 'C2 H5 N O2'       75.067  
HIS   'L-peptide linking'          y HISTIDINE ? 'C6 H10 N3 O2 1'   156.162 
ILE   'L-peptide linking'          y ISOLEUCINE ? 'C6 H13 N O2'      131.173 
LEU   'L-peptide linking'          y LEUCINE ? 'C6 H13 N O2'      131.173 
LYS   'L-peptide linking'          y LYSINE ? 'C6 H15 N2 O2 1'   147.195 
MET   'L-peptide linking'          y METHIONINE ? 'C5 H11 N O2 S'    149.211 
NAG   'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'      221.208 
PHE   'L-peptide linking'          y PHENYLALANINE ? 'C9 H11 N O2'      165.189 
PRO   'L-peptide linking'          y PROLINE ? 'C5 H9 N O2'       115.130 
SER   'L-peptide linking'          y SERINE ? 'C3 H7 N O3'       105.093 
THR   'L-peptide linking'          y THREONINE ? 'C4 H9 N O3'       119.119 
TRP   'L-peptide linking'          y TRYPTOPHAN ? 'C11 H12 N2 O2'    204.225 
TYR   'L-peptide linking'          y TYROSINE ? 'C9 H11 N O3'      181.189 
VAL   'L-peptide linking'          y VALINE ? 'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   27  ?   ?   ?   A . n 
A 1 2   PRO 2   28  ?   ?   ?   A . n 
A 1 3   ARG 3   29  ?   ?   ?   A . n 
A 1 4   GLN 4   30  ?   ?   ?   A . n 
A 1 5   ASP 5   31  31  ASP ASP A . n 
A 1 6   SER 6   32  32  SER SER A . n 
A 1 7   ARG 7   33  33  ARG ARG A . n 
A 1 8   ILE 8   34  34  ILE ILE A . n 
A 1 9   GLY 9   35  35  GLY GLY A . n 
A 1 10  LYS 10  36  36  LYS LYS A . n 
A 1 11  LEU 11  37  37  LEU LEU A . n 
A 1 12  LEU 12  38  38  LEU LEU A . n 
A 1 13  GLY 13  39  39  GLY GLY A . n 
A 1 14  PHE 14  40  40  PHE PHE A . n 
A 1 15  GLU 15  41  41  GLU GLU A . n 
A 1 16  TRP 16  42  42  TRP TRP A . n 
A 1 17  THR 17  43  43  THR THR A . n 
A 1 18  ASP 18  44  44  ASP ASP A . n 
A 1 19  LEU 19  45  45  LEU LEU A . n 
A 1 20  SER 20  46  46  SER SER A . n 
A 1 21  SER 21  47  47  SER SER A . n 
A 1 22  TRP 22  48  48  TRP TRP A . n 
A 1 23  ARG 23  49  49  ARG ARG A . n 
A 1 24  ARG 24  50  50  ARG ARG A . n 
A 1 25  LEU 25  51  51  LEU LEU A . n 
A 1 26  VAL 26  52  52  VAL VAL A . n 
A 1 27  THR 27  53  53  THR THR A . n 
A 1 28  LEU 28  54  54  LEU LEU A . n 
A 1 29  LEU 29  55  55  LEU LEU A . n 
A 1 30  ASN 30  56  56  ASN ASN A . n 
A 1 31  ARG 31  57  57  ARG ARG A . n 
A 1 32  PRO 32  58  58  PRO PRO A . n 
A 1 33  THR 33  59  59  THR THR A . n 
A 1 34  ASP 34  60  60  ASP ASP A . n 
A 1 35  PRO 35  61  61  PRO PRO A . n 
A 1 36  ALA 36  62  62  ALA ALA A . n 
A 1 37  SER 37  63  63  SER SER A . n 
A 1 38  LEU 38  64  64  LEU LEU A . n 
A 1 39  ALA 39  65  65  ALA ALA A . n 
A 1 40  VAL 40  66  66  VAL VAL A . n 
A 1 41  PHE 41  67  67  PHE PHE A . n 
A 1 42  ARG 42  68  68  ARG ARG A . n 
A 1 43  PHE 43  69  69  PHE PHE A . n 
A 1 44  LEU 44  70  70  LEU LEU A . n 
A 1 45  PHE 45  71  71  PHE PHE A . n 
A 1 46  GLY 46  72  72  GLY GLY A . n 
A 1 47  PHE 47  73  73  PHE PHE A . n 
A 1 48  LEU 48  74  74  LEU LEU A . n 
A 1 49  MET 49  75  75  MET MET A . n 
A 1 50  VAL 50  76  76  VAL VAL A . n 
A 1 51  LEU 51  77  77  LEU LEU A . n 
A 1 52  ASP 52  78  78  ASP ASP A . n 
A 1 53  ILE 53  79  79  ILE ILE A . n 
A 1 54  PRO 54  80  80  PRO PRO A . n 
A 1 55  GLN 55  81  81  GLN GLN A . n 
A 1 56  GLU 56  82  82  GLU GLU A . n 
A 1 57  ARG 57  83  83  ARG ARG A . n 
A 1 58  GLY 58  84  84  GLY GLY A . n 
A 1 59  LEU 59  85  85  LEU LEU A . n 
A 1 60  SER 60  86  86  SER SER A . n 
A 1 61  SER 61  87  87  SER SER A . n 
A 1 62  LEU 62  88  88  LEU LEU A . n 
A 1 63  ASP 63  89  89  ASP ASP A . n 
A 1 64  ARG 64  90  90  ARG ARG A . n 
A 1 65  LYS 65  91  91  LYS LYS A . n 
A 1 66  TYR 66  92  92  TYR TYR A . n 
A 1 67  LEU 67  93  93  LEU LEU A . n 
A 1 68  ASP 68  94  94  ASP ASP A . n 
A 1 69  GLY 69  95  95  GLY GLY A . n 
A 1 70  LEU 70  96  96  LEU LEU A . n 
A 1 71  ASP 71  97  97  ASP ASP A . n 
A 1 72  VAL 72  98  98  VAL VAL A . n 
A 1 73  CYS 73  99  99  CYS CYS A . n 
A 1 74  ARG 74  100 100 ARG ARG A . n 
A 1 75  PHE 75  101 101 PHE PHE A . n 
A 1 76  PRO 76  102 102 PRO PRO A . n 
A 1 77  LEU 77  103 103 LEU LEU A . n 
A 1 78  LEU 78  104 104 LEU LEU A . n 
A 1 79  ASP 79  105 105 ASP ASP A . n 
A 1 80  ALA 80  106 106 ALA ALA A . n 
A 1 81  LEU 81  107 107 LEU LEU A . n 
A 1 82  ARG 82  108 108 ARG ARG A . n 
A 1 83  PRO 83  109 109 PRO PRO A . n 
A 1 84  LEU 84  110 110 LEU LEU A . n 
A 1 85  PRO 85  111 111 PRO PRO A . n 
A 1 86  LEU 86  112 112 LEU LEU A . n 
A 1 87  ASP 87  113 113 ASP ASP A . n 
A 1 88  TRP 88  114 114 TRP TRP A . n 
A 1 89  MET 89  115 115 MET MET A . n 
A 1 90  TYR 90  116 116 TYR TYR A . n 
A 1 91  LEU 91  117 117 LEU LEU A . n 
A 1 92  VAL 92  118 118 VAL VAL A . n 
A 1 93  TYR 93  119 119 TYR TYR A . n 
A 1 94  THR 94  120 120 THR THR A . n 
A 1 95  ILE 95  121 121 ILE ILE A . n 
A 1 96  MET 96  122 122 MET MET A . n 
A 1 97  PHE 97  123 123 PHE PHE A . n 
A 1 98  LEU 98  124 124 LEU LEU A . n 
A 1 99  GLY 99  125 125 GLY GLY A . n 
A 1 100 ALA 100 126 126 ALA ALA A . n 
A 1 101 LEU 101 127 127 LEU LEU A . n 
A 1 102 GLY 102 128 128 GLY GLY A . n 
A 1 103 MET 103 129 129 MET MET A . n 
A 1 104 MET 104 130 130 MET MET A . n 
A 1 105 LEU 105 131 131 LEU LEU A . n 
A 1 106 GLY 106 132 132 GLY GLY A . n 
A 1 107 LEU 107 133 133 LEU LEU A . n 
A 1 108 CYS 108 134 134 CYS CYS A . n 
A 1 109 TYR 109 135 135 TYR TYR A . n 
A 1 110 ARG 110 136 136 ARG ARG A . n 
A 1 111 ILE 111 137 137 ILE ILE A . n 
A 1 112 SER 112 138 138 SER SER A . n 
A 1 113 CYS 113 139 139 CYS CYS A . n 
A 1 114 VAL 114 140 140 VAL VAL A . n 
A 1 115 LEU 115 141 141 LEU LEU A . n 
A 1 116 PHE 116 142 142 PHE PHE A . n 
A 1 117 LEU 117 143 143 LEU LEU A . n 
A 1 118 LEU 118 144 144 LEU LEU A . n 
A 1 119 PRO 119 145 145 PRO PRO A . n 
A 1 120 TYR 120 146 146 TYR TYR A . n 
A 1 121 TRP 121 147 147 TRP TRP A . n 
A 1 122 TYR 122 148 148 TYR TYR A . n 
A 1 123 VAL 123 149 149 VAL VAL A . n 
A 1 124 PHE 124 150 150 PHE PHE A . n 
A 1 125 LEU 125 151 151 LEU LEU A . n 
A 1 126 LEU 126 152 152 LEU LEU A . n 
A 1 127 ASP 127 153 153 ASP ASP A . n 
A 1 128 LYS 128 154 154 LYS LYS A . n 
A 1 129 THR 129 155 155 THR THR A . n 
A 1 130 SER 130 156 156 SER SER A . n 
A 1 131 TRP 131 157 157 TRP TRP A . n 
A 1 132 ASN 132 158 158 ASN ASN A . n 
A 1 133 ASN 133 159 159 ASN ASN A . n 
A 1 134 HIS 134 160 160 HIS HIS A . n 
A 1 135 SER 135 161 161 SER SER A . n 
A 1 136 TYR 136 162 162 TYR TYR A . n 
A 1 137 LEU 137 163 163 LEU LEU A . n 
A 1 138 TYR 138 164 164 TYR TYR A . n 
A 1 139 GLY 139 165 165 GLY GLY A . n 
A 1 140 LEU 140 166 166 LEU LEU A . n 
A 1 141 LEU 141 167 167 LEU LEU A . n 
A 1 142 ALA 142 168 168 ALA ALA A . n 
A 1 143 PHE 143 169 169 PHE PHE A . n 
A 1 144 GLN 144 170 170 GLN GLN A . n 
A 1 145 LEU 145 171 171 LEU LEU A . n 
A 1 146 THR 146 172 172 THR THR A . n 
A 1 147 PHE 147 173 173 PHE PHE A . n 
A 1 148 MET 148 174 174 MET MET A . n 
A 1 149 ASP 149 175 175 ASP ASP A . n 
A 1 150 ALA 150 176 176 ALA ALA A . n 
A 1 151 ASN 151 177 177 ASN ASN A . n 
A 1 152 HIS 152 178 178 HIS HIS A . n 
A 1 153 TYR 153 179 179 TYR TYR A . n 
A 1 154 TRP 154 180 180 TRP TRP A . n 
A 1 155 SER 155 181 181 SER SER A . n 
A 1 156 VAL 156 182 182 VAL VAL A . n 
A 1 157 ASP 157 183 183 ASP ASP A . n 
A 1 158 GLY 158 184 184 GLY GLY A . n 
A 1 159 LEU 159 185 185 LEU LEU A . n 
A 1 160 LEU 160 186 186 LEU LEU A . n 
A 1 161 ASN 161 187 187 ASN ASN A . n 
A 1 162 ALA 162 188 188 ALA ALA A . n 
A 1 163 HIS 163 189 189 HIS HIS A . n 
A 1 164 ARG 164 190 190 ARG ARG A . n 
A 1 165 ARG 165 191 191 ARG ARG A . n 
A 1 166 ASN 166 192 192 ASN ASN A . n 
A 1 167 ALA 167 193 193 ALA ALA A . n 
A 1 168 HIS 168 194 194 HIS HIS A . n 
A 1 169 VAL 169 195 195 VAL VAL A . n 
A 1 170 PRO 170 196 196 PRO PRO A . n 
A 1 171 LEU 171 197 197 LEU LEU A . n 
A 1 172 TRP 172 198 198 TRP TRP A . n 
A 1 173 ASN 173 199 199 ASN ASN A . n 
A 1 174 TYR 174 200 200 TYR TYR A . n 
A 1 175 ALA 175 201 201 ALA ALA A . n 
A 1 176 VAL 176 202 202 VAL VAL A . n 
A 1 177 LEU 177 203 203 LEU LEU A . n 
A 1 178 ARG 178 204 204 ARG ARG A . n 
A 1 179 GLY 179 205 205 GLY GLY A . n 
A 1 180 GLN 180 206 206 GLN GLN A . n 
A 1 181 ILE 181 207 207 ILE ILE A . n 
A 1 182 PHE 182 208 208 PHE PHE A . n 
A 1 183 ILE 183 209 209 ILE ILE A . n 
A 1 184 VAL 184 210 210 VAL VAL A . n 
A 1 185 TYR 185 211 211 TYR TYR A . n 
A 1 186 PHE 186 212 212 PHE PHE A . n 
A 1 187 ILE 187 213 213 ILE ILE A . n 
A 1 188 ALA 188 214 214 ALA ALA A . n 
A 1 189 GLY 189 215 215 GLY GLY A . n 
A 1 190 VAL 190 216 216 VAL VAL A . n 
A 1 191 LYS 191 217 217 LYS LYS A . n 
A 1 192 LYS 192 218 218 LYS LYS A . n 
A 1 193 LEU 193 219 219 LEU LEU A . n 
A 1 194 ASP 194 220 220 ASP ASP A . n 
A 1 195 ALA 195 221 221 ALA ALA A . n 
A 1 196 ASP 196 222 222 ASP ASP A . n 
A 1 197 TRP 197 223 223 TRP TRP A . n 
A 1 198 VAL 198 224 224 VAL VAL A . n 
A 1 199 GLU 199 225 225 GLU GLU A . n 
A 1 200 GLY 200 226 226 GLY GLY A . n 
A 1 201 TYR 201 227 227 TYR TYR A . n 
A 1 202 SER 202 228 228 SER SER A . n 
A 1 203 MET 203 229 229 MET MET A . n 
A 1 204 GLU 204 230 230 GLU GLU A . n 
A 1 205 TYR 205 231 231 TYR TYR A . n 
A 1 206 LEU 206 232 232 LEU LEU A . n 
A 1 207 SER 207 233 233 SER SER A . n 
A 1 208 ARG 208 234 234 ARG ARG A . n 
A 1 209 HIS 209 235 235 HIS HIS A . n 
A 1 210 TRP 210 236 236 TRP TRP A . n 
A 1 211 LEU 211 237 237 LEU LEU A . n 
A 1 212 PHE 212 238 238 PHE PHE A . n 
A 1 213 SER 213 239 239 SER SER A . n 
A 1 214 PRO 214 240 240 PRO PRO A . n 
A 1 215 PHE 215 241 241 PHE PHE A . n 
A 1 216 LYS 216 242 242 LYS LYS A . n 
A 1 217 LEU 217 243 243 LEU LEU A . n 
A 1 218 LEU 218 244 244 LEU LEU A . n 
A 1 219 LEU 219 245 245 LEU LEU A . n 
A 1 220 SER 220 246 246 SER SER A . n 
A 1 221 GLU 221 247 247 GLU GLU A . n 
A 1 222 GLU 222 248 248 GLU GLU A . n 
A 1 223 LEU 223 249 249 LEU LEU A . n 
A 1 224 THR 224 250 250 THR THR A . n 
A 1 225 SER 225 251 251 SER SER A . n 
A 1 226 LEU 226 252 252 LEU LEU A . n 
A 1 227 LEU 227 253 253 LEU LEU A . n 
A 1 228 VAL 228 254 254 VAL VAL A . n 
A 1 229 VAL 229 255 255 VAL VAL A . n 
A 1 230 HIS 230 256 256 HIS HIS A . n 
A 1 231 TRP 231 257 257 TRP TRP A . n 
A 1 232 GLY 232 258 258 GLY GLY A . n 
A 1 233 GLY 233 259 259 GLY GLY A . n 
A 1 234 LEU 234 260 260 LEU LEU A . n 
A 1 235 LEU 235 261 261 LEU LEU A . n 
A 1 236 LEU 236 262 262 LEU LEU A . n 
A 1 237 ASP 237 263 263 ASP ASP A . n 
A 1 238 LEU 238 264 264 LEU LEU A . n 
A 1 239 SER 239 265 265 SER SER A . n 
A 1 240 ALA 240 266 266 ALA ALA A . n 
A 1 241 GLY 241 267 267 GLY GLY A . n 
A 1 242 PHE 242 268 268 PHE PHE A . n 
A 1 243 LEU 243 269 269 LEU LEU A . n 
A 1 244 LEU 244 270 270 LEU LEU A . n 
A 1 245 PHE 245 271 271 PHE PHE A . n 
A 1 246 PHE 246 272 272 PHE PHE A . n 
A 1 247 ASP 247 273 273 ASP ASP A . n 
A 1 248 VAL 248 274 274 VAL VAL A . n 
A 1 249 SER 249 275 275 SER SER A . n 
A 1 250 ARG 250 276 276 ARG ARG A . n 
A 1 251 SER 251 277 277 SER SER A . n 
A 1 252 ILE 252 278 278 ILE ILE A . n 
A 1 253 GLY 253 279 279 GLY GLY A . n 
A 1 254 LEU 254 280 280 LEU LEU A . n 
A 1 255 PHE 255 281 281 PHE PHE A . n 
A 1 256 PHE 256 282 282 PHE PHE A . n 
A 1 257 VAL 257 283 283 VAL VAL A . n 
A 1 258 SER 258 284 284 SER SER A . n 
A 1 259 TYR 259 285 285 TYR TYR A . n 
A 1 260 PHE 260 286 286 PHE PHE A . n 
A 1 261 HIS 261 287 287 HIS HIS A . n 
A 1 262 CYS 262 288 288 CYS CYS A . n 
A 1 263 MET 263 289 289 MET MET A . n 
A 1 264 ASN 264 290 290 ASN ASN A . n 
A 1 265 SER 265 291 291 SER SER A . n 
A 1 266 GLN 266 292 292 GLN GLN A . n 
A 1 267 LEU 267 293 293 LEU LEU A . n 
A 1 268 PHE 268 294 294 PHE PHE A . n 
A 1 269 SER 269 295 295 SER SER A . n 
A 1 270 ILE 270 296 296 ILE ILE A . n 
A 1 271 GLY 271 297 297 GLY GLY A . n 
A 1 272 MET 272 298 298 MET MET A . n 
A 1 273 PHE 273 299 299 PHE PHE A . n 
A 1 274 SER 274 300 300 SER SER A . n 
A 1 275 TYR 275 301 301 TYR TYR A . n 
A 1 276 VAL 276 302 302 VAL VAL A . n 
A 1 277 MET 277 303 303 MET MET A . n 
A 1 278 LEU 278 304 304 LEU LEU A . n 
A 1 279 ALA 279 305 305 ALA ALA A . n 
A 1 280 SER 280 306 306 SER SER A . n 
A 1 281 SER 281 307 307 SER SER A . n 
A 1 282 PRO 282 308 308 PRO PRO A . n 
A 1 283 LEU 283 309 309 LEU LEU A . n 
A 1 284 PHE 284 310 310 PHE PHE A . n 
A 1 285 CYS 285 311 311 CYS CYS A . n 
A 1 286 SER 286 312 312 SER SER A . n 
A 1 287 PRO 287 313 313 PRO PRO A . n 
A 1 288 GLU 288 314 314 GLU GLU A . n 
A 1 289 TRP 289 315 315 TRP TRP A . n 
A 1 290 PRO 290 316 316 PRO PRO A . n 
A 1 291 ARG 291 317 317 ARG ARG A . n 
A 1 292 LYS 292 318 318 LYS LYS A . n 
A 1 293 LEU 293 319 319 LEU LEU A . n 
A 1 294 VAL 294 320 320 VAL VAL A . n 
A 1 295 SER 295 321 321 SER SER A . n 
A 1 296 TYR 296 322 322 TYR TYR A . n 
A 1 297 CYS 297 323 323 CYS CYS A . n 
A 1 298 PRO 298 324 324 PRO PRO A . n 
A 1 299 ARG 299 325 325 ARG ARG A . n 
A 1 300 ARG 300 326 326 ARG ARG A . n 
A 1 301 LEU 301 327 327 LEU LEU A . n 
A 1 302 GLN 302 328 328 GLN GLN A . n 
A 1 303 GLN 303 329 329 GLN GLN A . n 
A 1 304 LEU 304 330 330 LEU LEU A . n 
A 1 305 LEU 305 331 331 LEU LEU A . n 
A 1 306 PRO 306 332 332 PRO PRO A . n 
A 1 307 LEU 307 333 333 LEU LEU A . n 
A 1 308 LYS 308 334 334 LYS LYS A . n 
A 1 309 ALA 309 335 335 ALA ALA A . n 
A 1 310 ALA 310 336 336 ALA ALA A . n 
A 1 311 PRO 311 337 337 PRO PRO A . n 
A 1 312 GLN 312 338 338 GLN GLN A . n 
A 1 313 PRO 313 339 339 PRO PRO A . n 
A 1 314 SER 314 340 340 SER SER A . n 
A 1 315 VAL 315 341 341 VAL VAL A . n 
A 1 316 SER 316 342 342 SER SER A . n 
A 1 317 CYS 317 343 343 CYS CYS A . n 
A 1 318 VAL 318 344 344 VAL VAL A . n 
A 1 319 TYR 319 345 345 TYR TYR A . n 
A 1 320 LYS 320 346 346 LYS LYS A . n 
A 1 321 ARG 321 347 347 ARG ARG A . n 
A 1 322 SER 322 348 ?   ?   ?   A . n 
A 1 323 ARG 323 349 ?   ?   ?   A . n 
A 1 324 GLY 324 350 ?   ?   ?   A . n 
A 1 325 LYS 325 351 ?   ?   ?   A . n 
A 1 326 SER 326 352 ?   ?   ?   A . n 
A 1 327 GLY 327 353 353 GLY GLY A . n 
A 1 328 GLN 328 354 354 GLN GLN A . n 
A 1 329 LYS 329 355 355 LYS LYS A . n 
A 1 330 PRO 330 356 356 PRO PRO A . n 
A 1 331 GLY 331 357 357 GLY GLY A . n 
A 1 332 LEU 332 358 358 LEU LEU A . n 
A 1 333 ARG 333 359 359 ARG ARG A . n 
A 1 334 HIS 334 360 360 HIS HIS A . n 
A 1 335 GLN 335 361 361 GLN GLN A . n 
A 1 336 LEU 336 362 362 LEU LEU A . n 
A 1 337 GLY 337 363 363 GLY GLY A . n 
A 1 338 ALA 338 364 364 ALA ALA A . n 
A 1 339 ALA 339 365 365 ALA ALA A . n 
A 1 340 PHE 340 366 366 PHE PHE A . n 
A 1 341 THR 341 367 367 THR THR A . n 
A 1 342 LEU 342 368 368 LEU LEU A . n 
A 1 343 LEU 343 369 369 LEU LEU A . n 
A 1 344 TYR 344 370 370 TYR TYR A . n 
A 1 345 LEU 345 371 371 LEU LEU A . n 
A 1 346 LEU 346 372 372 LEU LEU A . n 
A 1 347 GLU 347 373 373 GLU GLU A . n 
A 1 348 GLN 348 374 374 GLN GLN A . n 
A 1 349 LEU 349 375 375 LEU LEU A . n 
A 1 350 PHE 350 376 376 PHE PHE A . n 
A 1 351 LEU 351 377 377 LEU LEU A . n 
A 1 352 PRO 352 378 378 PRO PRO A . n 
A 1 353 TYR 353 379 379 TYR TYR A . n 
A 1 354 SER 354 380 380 SER SER A . n 
A 1 355 HIS 355 381 381 HIS HIS A . n 
A 1 356 PHE 356 382 382 PHE PHE A . n 
A 1 357 LEU 357 383 383 LEU LEU A . n 
A 1 358 THR 358 384 384 THR THR A . n 
A 1 359 GLN 359 385 385 GLN GLN A . n 
A 1 360 GLY 360 386 386 GLY GLY A . n 
A 1 361 TYR 361 387 387 TYR TYR A . n 
A 1 362 ASN 362 388 388 ASN ASN A . n 
A 1 363 ASN 363 389 389 ASN ASN A . n 
A 1 364 TRP 364 390 390 TRP TRP A . n 
A 1 365 THR 365 391 391 THR THR A . n 
A 1 366 ASN 366 392 392 ASN ASN A . n 
A 1 367 GLY 367 393 393 GLY GLY A . n 
A 1 368 LEU 368 394 394 LEU LEU A . n 
A 1 369 TYR 369 395 395 TYR TYR A . n 
A 1 370 GLY 370 396 396 GLY GLY A . n 
A 1 371 TYR 371 397 397 TYR TYR A . n 
A 1 372 SER 372 398 398 SER SER A . n 
A 1 373 TRP 373 399 399 TRP TRP A . n 
A 1 374 ASP 374 400 400 ASP ASP A . n 
A 1 375 MET 375 401 401 MET MET A . n 
A 1 376 MET 376 402 402 MET MET A . n 
A 1 377 VAL 377 403 403 VAL VAL A . n 
A 1 378 HIS 378 404 404 HIS HIS A . n 
A 1 379 SER 379 405 405 SER SER A . n 
A 1 380 ARG 380 406 406 ARG ARG A . n 
A 1 381 SER 381 407 407 SER SER A . n 
A 1 382 HIS 382 408 408 HIS HIS A . n 
A 1 383 GLN 383 409 409 GLN GLN A . n 
A 1 384 HIS 384 410 410 HIS HIS A . n 
A 1 385 VAL 385 411 411 VAL VAL A . n 
A 1 386 LYS 386 412 412 LYS LYS A . n 
A 1 387 ILE 387 413 413 ILE ILE A . n 
A 1 388 THR 388 414 414 THR THR A . n 
A 1 389 TYR 389 415 415 TYR TYR A . n 
A 1 390 ARG 390 416 416 ARG ARG A . n 
A 1 391 ASP 391 417 417 ASP ASP A . n 
A 1 392 GLY 392 418 418 GLY GLY A . n 
A 1 393 ARG 393 419 419 ARG ARG A . n 
A 1 394 THR 394 420 420 THR THR A . n 
A 1 395 GLY 395 421 421 GLY GLY A . n 
A 1 396 GLU 396 422 422 GLU GLU A . n 
A 1 397 LEU 397 423 423 LEU LEU A . n 
A 1 398 GLY 398 424 424 GLY GLY A . n 
A 1 399 TYR 399 425 425 TYR TYR A . n 
A 1 400 LEU 400 426 426 LEU LEU A . n 
A 1 401 ASN 401 427 427 ASN ASN A . n 
A 1 402 PRO 402 428 428 PRO PRO A . n 
A 1 403 GLY 403 429 429 GLY GLY A . n 
A 1 404 VAL 404 430 430 VAL VAL A . n 
A 1 405 PHE 405 431 431 PHE PHE A . n 
A 1 406 THR 406 432 432 THR THR A . n 
A 1 407 GLN 407 433 433 GLN GLN A . n 
A 1 408 SER 408 434 434 SER SER A . n 
A 1 409 ARG 409 435 435 ARG ARG A . n 
A 1 410 ARG 410 436 436 ARG ARG A . n 
A 1 411 TRP 411 437 437 TRP TRP A . n 
A 1 412 LYS 412 438 438 LYS LYS A . n 
A 1 413 ASP 413 439 439 ASP ASP A . n 
A 1 414 HIS 414 440 440 HIS HIS A . n 
A 1 415 ALA 415 441 441 ALA ALA A . n 
A 1 416 ASP 416 442 442 ASP ASP A . n 
A 1 417 MET 417 443 443 MET MET A . n 
A 1 418 LEU 418 444 444 LEU LEU A . n 
A 1 419 LYS 419 445 445 LYS LYS A . n 
A 1 420 GLN 420 446 446 GLN GLN A . n 
A 1 421 TYR 421 447 447 TYR TYR A . n 
A 1 422 ALA 422 448 448 ALA ALA A . n 
A 1 423 THR 423 449 449 THR THR A . n 
A 1 424 CYS 424 450 450 CYS CYS A . n 
A 1 425 LEU 425 451 451 LEU LEU A . n 
A 1 426 SER 426 452 452 SER SER A . n 
A 1 427 ARG 427 453 453 ARG ARG A . n 
A 1 428 LEU 428 454 454 LEU LEU A . n 
A 1 429 LEU 429 455 455 LEU LEU A . n 
A 1 430 PRO 430 456 456 PRO PRO A . n 
A 1 431 LYS 431 457 457 LYS LYS A . n 
A 1 432 TYR 432 458 458 TYR TYR A . n 
A 1 433 ASN 433 459 459 ASN ASN A . n 
A 1 434 VAL 434 460 460 VAL VAL A . n 
A 1 435 THR 435 461 461 THR THR A . n 
A 1 436 GLU 436 462 462 GLU GLU A . n 
A 1 437 PRO 437 463 463 PRO PRO A . n 
A 1 438 GLN 438 464 464 GLN GLN A . n 
A 1 439 ILE 439 465 465 ILE ILE A . n 
A 1 440 TYR 440 466 466 TYR TYR A . n 
A 1 441 PHE 441 467 467 PHE PHE A . n 
A 1 442 ASP 442 468 468 ASP ASP A . n 
A 1 443 ILE 443 469 469 ILE ILE A . n 
A 1 444 TRP 444 470 470 TRP TRP A . n 
A 1 445 VAL 445 471 471 VAL VAL A . n 
A 1 446 SER 446 472 472 SER SER A . n 
A 1 447 ILE 447 473 473 ILE ILE A . n 
A 1 448 ASN 448 474 474 ASN ASN A . n 
A 1 449 ASP 449 475 475 ASP ASP A . n 
A 1 450 ARG 450 476 476 ARG ARG A . n 
A 1 451 PHE 451 477 477 PHE PHE A . n 
A 1 452 GLN 452 478 478 GLN GLN A . n 
A 1 453 GLN 453 479 479 GLN GLN A . n 
A 1 454 ARG 454 480 480 ARG ARG A . n 
A 1 455 ILE 455 481 481 ILE ILE A . n 
A 1 456 PHE 456 482 482 PHE PHE A . n 
A 1 457 ASP 457 483 483 ASP ASP A . n 
A 1 458 PRO 458 484 484 PRO PRO A . n 
A 1 459 ARG 459 485 485 ARG ARG A . n 
A 1 460 VAL 460 486 486 VAL VAL A . n 
A 1 461 ASP 461 487 487 ASP ASP A . n 
A 1 462 ILE 462 488 488 ILE ILE A . n 
A 1 463 VAL 463 489 489 VAL VAL A . n 
A 1 464 GLN 464 490 490 GLN GLN A . n 
A 1 465 ALA 465 491 491 ALA ALA A . n 
A 1 466 ALA 466 492 492 ALA ALA A . n 
A 1 467 TRP 467 493 493 TRP TRP A . n 
A 1 468 SER 468 494 494 SER SER A . n 
A 1 469 PRO 469 495 495 PRO PRO A . n 
A 1 470 PHE 470 496 496 PHE PHE A . n 
A 1 471 GLN 471 497 497 GLN GLN A . n 
A 1 472 ARG 472 498 498 ARG ARG A . n 
A 1 473 THR 473 499 499 THR THR A . n 
A 1 474 SER 474 500 500 SER SER A . n 
A 1 475 TRP 475 501 501 TRP TRP A . n 
A 1 476 VAL 476 502 502 VAL VAL A . n 
A 1 477 GLN 477 503 503 GLN GLN A . n 
A 1 478 PRO 478 504 504 PRO PRO A . n 
A 1 479 LEU 479 505 505 LEU LEU A . n 
A 1 480 LEU 480 506 506 LEU LEU A . n 
A 1 481 MET 481 507 507 MET MET A . n 
A 1 482 ASP 482 508 508 ASP ASP A . n 
A 1 483 LEU 483 509 509 LEU LEU A . n 
A 1 484 SER 484 510 510 SER SER A . n 
A 1 485 PRO 485 511 511 PRO PRO A . n 
A 1 486 TRP 486 512 512 TRP TRP A . n 
A 1 487 ARG 487 513 513 ARG ARG A . n 
A 1 488 ALA 488 514 514 ALA ALA A . n 
A 1 489 LYS 489 515 515 LYS LYS A . n 
A 1 490 LEU 490 516 516 LEU LEU A . n 
A 1 491 GLN 491 517 517 GLN GLN A . n 
A 1 492 GLU 492 518 518 GLU GLU A . n 
A 1 493 ILE 493 519 519 ILE ILE A . n 
A 1 494 LYS 494 520 520 LYS LYS A . n 
A 1 495 SER 495 521 521 SER SER A . n 
A 1 496 SER 496 522 522 SER SER A . n 
A 1 497 LEU 497 523 523 LEU LEU A . n 
A 1 498 ASP 498 524 524 ASP ASP A . n 
A 1 499 ASN 499 525 525 ASN ASN A . n 
A 1 500 HIS 500 526 526 HIS HIS A . n 
A 1 501 THR 501 527 527 THR THR A . n 
A 1 502 GLU 502 528 528 GLU GLU A . n 
A 1 503 VAL 503 529 529 VAL VAL A . n 
A 1 504 VAL 504 530 530 VAL VAL A . n 
A 1 505 PHE 505 531 531 PHE PHE A . n 
A 1 506 ILE 506 532 532 ILE ILE A . n 
A 1 507 ALA 507 533 533 ALA ALA A . n 
A 1 508 ASP 508 534 534 ASP ASP A . n 
A 1 509 PHE 509 535 535 PHE PHE A . n 
A 1 510 PRO 510 536 536 PRO PRO A . n 
A 1 511 GLY 511 537 537 GLY GLY A . n 
A 1 512 LEU 512 538 538 LEU LEU A . n 
A 1 513 HIS 513 539 539 HIS HIS A . n 
A 1 514 LEU 514 540 540 LEU LEU A . n 
A 1 515 GLU 515 541 541 GLU GLU A . n 
A 1 516 ASN 516 542 542 ASN ASN A . n 
A 1 517 PHE 517 543 543 PHE PHE A . n 
A 1 518 VAL 518 544 544 VAL VAL A . n 
A 1 519 SER 519 545 545 SER SER A . n 
A 1 520 GLU 520 546 546 GLU GLU A . n 
A 1 521 ASP 521 547 547 ASP ASP A . n 
A 1 522 LEU 522 548 548 LEU LEU A . n 
A 1 523 GLY 523 549 549 GLY GLY A . n 
A 1 524 ASN 524 550 550 ASN ASN A . n 
A 1 525 THR 525 551 551 THR THR A . n 
A 1 526 SER 526 552 552 SER SER A . n 
A 1 527 ILE 527 553 553 ILE ILE A . n 
A 1 528 GLN 528 554 554 GLN GLN A . n 
A 1 529 LEU 529 555 555 LEU LEU A . n 
A 1 530 LEU 530 556 556 LEU LEU A . n 
A 1 531 GLN 531 557 557 GLN GLN A . n 
A 1 532 GLY 532 558 558 GLY GLY A . n 
A 1 533 GLU 533 559 559 GLU GLU A . n 
A 1 534 VAL 534 560 560 VAL VAL A . n 
A 1 535 THR 535 561 561 THR THR A . n 
A 1 536 VAL 536 562 562 VAL VAL A . n 
A 1 537 GLU 537 563 563 GLU GLU A . n 
A 1 538 LEU 538 564 564 LEU LEU A . n 
A 1 539 VAL 539 565 565 VAL VAL A . n 
A 1 540 ALA 540 566 566 ALA ALA A . n 
A 1 541 GLU 541 567 567 GLU GLU A . n 
A 1 542 GLN 542 568 568 GLN GLN A . n 
A 1 543 LYS 543 569 569 LYS LYS A . n 
A 1 544 ASN 544 570 570 ASN ASN A . n 
A 1 545 GLN 545 571 571 GLN GLN A . n 
A 1 546 THR 546 572 572 THR THR A . n 
A 1 547 LEU 547 573 573 LEU LEU A . n 
A 1 548 ARG 548 574 574 ARG ARG A . n 
A 1 549 GLU 549 575 575 GLU GLU A . n 
A 1 550 GLY 550 576 576 GLY GLY A . n 
A 1 551 GLU 551 577 577 GLU GLU A . n 
A 1 552 LYS 552 578 578 LYS LYS A . n 
A 1 553 MET 553 579 579 MET MET A . n 
A 1 554 GLN 554 580 580 GLN GLN A . n 
A 1 555 LEU 555 581 581 LEU LEU A . n 
A 1 556 PRO 556 582 582 PRO PRO A . n 
A 1 557 ALA 557 583 583 ALA ALA A . n 
A 1 558 GLY 558 584 584 GLY GLY A . n 
A 1 559 GLU 559 585 585 GLU GLU A . n 
A 1 560 TYR 560 586 586 TYR TYR A . n 
A 1 561 HIS 561 587 587 HIS HIS A . n 
A 1 562 LYS 562 588 588 LYS LYS A . n 
A 1 563 VAL 563 589 589 VAL VAL A . n 
A 1 564 TYR 564 590 590 TYR TYR A . n 
A 1 565 THR 565 591 591 THR THR A . n 
A 1 566 THR 566 592 592 THR THR A . n 
A 1 567 SER 567 593 593 SER SER A . n 
A 1 568 PRO 568 594 594 PRO PRO A . n 
A 1 569 SER 569 595 595 SER SER A . n 
A 1 570 PRO 570 596 596 PRO PRO A . n 
A 1 571 SER 571 597 597 SER SER A . n 
A 1 572 CYS 572 598 598 CYS CYS A . n 
A 1 573 TYR 573 599 599 TYR TYR A . n 
A 1 574 MET 574 600 600 MET MET A . n 
A 1 575 TYR 575 601 601 TYR TYR A . n 
A 1 576 VAL 576 602 602 VAL VAL A . n 
A 1 577 TYR 577 603 603 TYR TYR A . n 
A 1 578 VAL 578 604 604 VAL VAL A . n 
A 1 579 ASN 579 605 605 ASN ASN A . n 
A 1 580 THR 580 606 606 THR THR A . n 
A 1 581 THR 581 607 607 THR THR A . n 
A 1 582 GLU 582 608 608 GLU GLU A . n 
A 1 583 LEU 583 609 609 LEU LEU A . n 
A 1 584 ALA 584 610 610 ALA ALA A . n 
A 1 585 LEU 585 611 611 LEU LEU A . n 
A 1 586 GLU 586 612 612 GLU GLU A . n 
A 1 587 GLN 587 613 613 GLN GLN A . n 
A 1 588 ASP 588 614 614 ASP ASP A . n 
A 1 589 LEU 589 615 615 LEU LEU A . n 
A 1 590 ALA 590 616 616 ALA ALA A . n 
A 1 591 TYR 591 617 617 TYR TYR A . n 
A 1 592 LEU 592 618 618 LEU LEU A . n 
A 1 593 GLN 593 619 619 GLN GLN A . n 
A 1 594 GLU 594 620 620 GLU GLU A . n 
A 1 595 LEU 595 621 621 LEU LEU A . n 
A 1 596 LYS 596 622 622 LYS LYS A . n 
A 1 597 GLU 597 623 623 GLU GLU A . n 
A 1 598 LYS 598 624 624 LYS LYS A . n 
A 1 599 VAL 599 625 625 VAL VAL A . n 
A 1 600 GLU 600 626 626 GLU GLU A . n 
A 1 601 ASN 601 627 627 ASN ASN A . n 
A 1 602 GLY 602 628 628 GLY GLY A . n 
A 1 603 SER 603 629 629 SER SER A . n 
A 1 604 GLU 604 630 630 GLU GLU A . n 
A 1 605 THR 605 631 631 THR THR A . n 
A 1 606 GLY 606 632 632 GLY GLY A . n 
A 1 607 PRO 607 633 633 PRO PRO A . n 
A 1 608 LEU 608 634 634 LEU LEU A . n 
A 1 609 PRO 609 635 635 PRO PRO A . n 
A 1 610 PRO 610 636 636 PRO PRO A . n 
A 1 611 GLU 611 637 637 GLU GLU A . n 
A 1 612 LEU 612 638 638 LEU LEU A . n 
A 1 613 GLN 613 639 639 GLN GLN A . n 
A 1 614 PRO 614 640 640 PRO PRO A . n 
A 1 615 LEU 615 641 641 LEU LEU A . n 
A 1 616 LEU 616 642 642 LEU LEU A . n 
A 1 617 GLU 617 643 643 GLU GLU A . n 
A 1 618 GLY 618 644 644 GLY GLY A . n 
A 1 619 GLU 619 645 645 GLU GLU A . n 
A 1 620 VAL 620 646 646 VAL VAL A . n 
A 1 621 LYS 621 647 647 LYS LYS A . n 
A 1 622 GLY 622 648 648 GLY GLY A . n 
A 1 623 GLY 623 649 649 GLY GLY A . n 
A 1 624 PRO 624 650 650 PRO PRO A . n 
A 1 625 GLU 625 651 651 GLU GLU A . n 
A 1 626 PRO 626 652 652 PRO PRO A . n 
A 1 627 THR 627 653 653 THR THR A . n 
A 1 628 PRO 628 654 654 PRO PRO A . n 
A 1 629 LEU 629 655 655 LEU LEU A . n 
A 1 630 VAL 630 656 656 VAL VAL A . n 
A 1 631 GLN 631 657 657 GLN GLN A . n 
A 1 632 THR 632 658 658 THR THR A . n 
A 1 633 PHE 633 659 659 PHE PHE A . n 
A 1 634 LEU 634 660 660 LEU LEU A . n 
A 1 635 ARG 635 661 661 ARG ARG A . n 
A 1 636 ARG 636 662 662 ARG ARG A . n 
A 1 637 GLN 637 663 663 GLN GLN A . n 
A 1 638 GLN 638 664 664 GLN GLN A . n 
A 1 639 ARG 639 665 665 ARG ARG A . n 
A 1 640 LEU 640 666 666 LEU LEU A . n 
A 1 641 GLN 641 667 667 GLN GLN A . n 
A 1 642 GLU 642 668 668 GLU GLU A . n 
A 1 643 ILE 643 669 669 ILE ILE A . n 
A 1 644 GLU 644 670 670 GLU GLU A . n 
A 1 645 ARG 645 671 671 ARG ARG A . n 
A 1 646 ARG 646 672 672 ARG ARG A . n 
A 1 647 ARG 647 673 673 ARG ARG A . n 
A 1 648 ASN 648 674 674 ASN ASN A . n 
A 1 649 THR 649 675 675 THR THR A . n 
A 1 650 PRO 650 676 676 PRO PRO A . n 
A 1 651 PHE 651 677 677 PHE PHE A . n 
A 1 652 HIS 652 678 678 HIS HIS A . n 
A 1 653 GLU 653 679 679 GLU GLU A . n 
A 1 654 ARG 654 680 680 ARG ARG A . n 
A 1 655 PHE 655 681 681 PHE PHE A . n 
A 1 656 PHE 656 682 682 PHE PHE A . n 
A 1 657 ARG 657 683 683 ARG ARG A . n 
A 1 658 PHE 658 684 684 PHE PHE A . n 
A 1 659 LEU 659 685 685 LEU LEU A . n 
A 1 660 LEU 660 686 686 LEU LEU A . n 
A 1 661 ARG 661 687 687 ARG ARG A . n 
A 1 662 LYS 662 688 688 LYS LYS A . n 
A 1 663 LEU 663 689 689 LEU LEU A . n 
A 1 664 TYR 664 690 690 TYR TYR A . n 
A 1 665 VAL 665 691 691 VAL VAL A . n 
A 1 666 PHE 666 692 692 PHE PHE A . n 
A 1 667 ARG 667 693 693 ARG ARG A . n 
A 1 668 ARG 668 694 694 ARG ARG A . n 
A 1 669 SER 669 695 695 SER SER A . n 
A 1 670 PHE 670 696 696 PHE PHE A . n 
A 1 671 LEU 671 697 697 LEU LEU A . n 
A 1 672 MET 672 698 698 MET MET A . n 
A 1 673 THR 673 699 699 THR THR A . n 
A 1 674 CYS 674 700 700 CYS CYS A . n 
A 1 675 ILE 675 701 701 ILE ILE A . n 
A 1 676 SER 676 702 702 SER SER A . n 
A 1 677 LEU 677 703 703 LEU LEU A . n 
A 1 678 ARG 678 704 704 ARG ARG A . n 
A 1 679 ASN 679 705 705 ASN ASN A . n 
A 1 680 LEU 680 706 706 LEU LEU A . n 
A 1 681 ILE 681 707 707 ILE ILE A . n 
A 1 682 LEU 682 708 708 LEU LEU A . n 
A 1 683 GLY 683 709 709 GLY GLY A . n 
A 1 684 ARG 684 710 710 ARG ARG A . n 
A 1 685 PRO 685 711 711 PRO PRO A . n 
A 1 686 SER 686 712 712 SER SER A . n 
A 1 687 LEU 687 713 713 LEU LEU A . n 
A 1 688 GLU 688 714 714 GLU GLU A . n 
A 1 689 GLN 689 715 715 GLN GLN A . n 
A 1 690 LEU 690 716 716 LEU LEU A . n 
A 1 691 ALA 691 717 717 ALA ALA A . n 
A 1 692 GLN 692 718 718 GLN GLN A . n 
A 1 693 GLU 693 719 719 GLU GLU A . n 
A 1 694 VAL 694 720 720 VAL VAL A . n 
A 1 695 THR 695 721 721 THR THR A . n 
A 1 696 TYR 696 722 722 TYR TYR A . n 
A 1 697 ALA 697 723 723 ALA ALA A . n 
A 1 698 ASN 698 724 724 ASN ASN A . n 
A 1 699 LEU 699 725 725 LEU LEU A . n 
A 1 700 ARG 700 726 726 ARG ARG A . n 
A 1 701 PRO 701 727 727 PRO PRO A . n 
A 1 702 PHE 702 728 728 PHE PHE A . n 
A 1 703 GLU 703 729 ?   ?   ?   A . n 
A 1 704 ALA 704 730 ?   ?   ?   A . n 
A 1 705 VAL 705 731 ?   ?   ?   A . n 
A 1 706 GLY 706 732 ?   ?   ?   A . n 
A 1 707 GLU 707 733 ?   ?   ?   A . n 
A 1 708 LEU 708 734 ?   ?   ?   A . n 
A 1 709 ASN 709 735 ?   ?   ?   A . n 
A 1 710 PRO 710 736 ?   ?   ?   A . n 
A 1 711 SER 711 737 ?   ?   ?   A . n 
A 1 712 ASN 712 738 ?   ?   ?   A . n 
A 1 713 THR 713 739 ?   ?   ?   A . n 
A 1 714 ASP 714 740 ?   ?   ?   A . n 
A 1 715 SER 715 741 ?   ?   ?   A . n 
A 1 716 SER 716 742 ?   ?   ?   A . n 
A 1 717 HIS 717 743 ?   ?   ?   A . n 
A 1 718 SER 718 744 ?   ?   ?   A . n 
A 1 719 ASN 719 745 ?   ?   ?   A . n 
A 1 720 PRO 720 746 ?   ?   ?   A . n 
A 1 721 PRO 721 747 ?   ?   ?   A . n 
A 1 722 GLU 722 748 ?   ?   ?   A . n 
A 1 723 SER 723 749 ?   ?   ?   A . n 
A 1 724 ASN 724 750 ?   ?   ?   A . n 
A 1 725 PRO 725 751 ?   ?   ?   A . n 
A 1 726 ASP 726 752 ?   ?   ?   A . n 
A 1 727 PRO 727 753 ?   ?   ?   A . n 
A 1 728 VAL 728 754 ?   ?   ?   A . n 
A 1 729 HIS 729 755 ?   ?   ?   A . n 
A 1 730 SER 730 756 ?   ?   ?   A . n 
A 1 731 GLU 731 757 ?   ?   ?   A . n 
A 1 732 PHE 732 758 ?   ?   ?   A . n 
B 2 1   THR 1   19  ?   ?   ?   P . n 
B 2 2   PRO 2   20  ?   ?   ?   P . n 
B 2 3   ALA 3   21  ?   ?   ?   P . n 
B 2 4   PRO 4   22  ?   ?   ?   P . n 
B 2 5   LEU 5   23  23  LEU LEU P . n 
B 2 6   ASP 6   24  24  ASP ASP P . n 
B 2 7   SER 7   25  25  SER SER P . n 
B 2 8   VAL 8   26  26  VAL VAL P . n 
B 2 9   PHE 9   27  27  PHE PHE P . n 
B 2 10  SER 10  28  28  SER SER P . n 
B 2 11  SER 11  29  29  SER SER P . n 
B 2 12  SER 12  30  30  SER SER P . n 
B 2 13  GLU 13  31  31  GLU GLU P . n 
B 2 14  ARG 14  32  32  ARG ARG P . n 
B 2 15  ALA 15  33  33  ALA ALA P . n 
B 2 16  HIS 16  34  34  HIS HIS P . n 
B 2 17  GLN 17  35  35  GLN GLN P . n 
B 2 18  VAL 18  36  36  VAL VAL P . n 
B 2 19  LEU 19  37  37  LEU LEU P . n 
B 2 20  ARG 20  38  38  ARG ARG P . n 
B 2 21  ILE 21  39  39  ILE ILE P . n 
B 2 22  ARG 22  40  40  ARG ARG P . n 
B 2 23  LYS 23  41  41  LYS LYS P . n 
B 2 24  ARG 24  42  42  ARG ARG P . n 
B 2 25  ALA 25  43  43  ALA ALA P . n 
B 2 26  ASN 26  44  44  ASN ASN P . n 
B 2 27  SER 27  45  45  SER SER P . n 
B 2 28  PHE 28  46  46  PHE PHE P . n 
B 2 29  LEU 29  47  47  LEU LEU P . n 
B 2 30  GLU 30  48  48  GLU GLU P . n 
B 2 31  GLU 31  49  49  GLU GLU P . n 
B 2 32  LEU 32  50  50  LEU LEU P . n 
B 2 33  ARG 33  51  51  ARG ARG P . n 
B 2 34  HIS 34  52  52  HIS HIS P . n 
B 2 35  SER 35  53  53  SER SER P . n 
B 2 36  SER 36  54  54  SER SER P . n 
B 2 37  LEU 37  55  55  LEU LEU P . n 
B 2 38  GLU 38  56  56  GLU GLU P . n 
B 2 39  ARG 39  57  57  ARG ARG P . n 
B 2 40  GLU 40  58  ?   ?   ?   P . n 
B 2 41  CYS 41  59  ?   ?   ?   P . n 
B 2 42  ILE 42  60  ?   ?   ?   P . n 
B 2 43  GLU 43  61  ?   ?   ?   P . n 
B 2 44  GLU 44  62  ?   ?   ?   P . n 
B 2 45  ILE 45  63  ?   ?   ?   P . n 
B 2 46  CYS 46  64  ?   ?   ?   P . n 
B 2 47  ASP 47  65  ?   ?   ?   P . n 
B 2 48  PHE 48  66  ?   ?   ?   P . n 
B 2 49  GLU 49  67  ?   ?   ?   P . n 
B 2 50  GLU 50  68  ?   ?   ?   P . n 
B 2 51  ALA 51  69  ?   ?   ?   P . n 
B 2 52  LYS 52  70  ?   ?   ?   P . n 
B 2 53  GLU 53  71  ?   ?   ?   P . n 
B 2 54  ILE 54  72  ?   ?   ?   P . n 
B 2 55  PHE 55  73  ?   ?   ?   P . n 
B 2 56  GLN 56  74  ?   ?   ?   P . n 
B 2 57  ASN 57  75  ?   ?   ?   P . n 
B 2 58  VAL 58  76  ?   ?   ?   P . n 
B 2 59  ASP 59  77  ?   ?   ?   P . n 
B 2 60  ASP 60  78  ?   ?   ?   P . n 
B 2 61  THR 61  79  ?   ?   ?   P . n 
B 2 62  LEU 62  80  ?   ?   ?   P . n 
B 2 63  ALA 63  81  ?   ?   ?   P . n 
B 2 64  PHE 64  82  ?   ?   ?   P . n 
B 2 65  TRP 65  83  ?   ?   ?   P . n 
B 2 66  SER 66  84  ?   ?   ?   P . n 
B 2 67  LYS 67  85  ?   ?   ?   P . n 
B 2 68  HIS 68  86  ?   ?   ?   P . n 
B 2 69  VAL 69  87  ?   ?   ?   P . n 
B 2 70  ASP 70  88  ?   ?   ?   P . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
C 3 NAG 1 B NAG 1 B NAG 1 n 
C 3 NAG 2 B NAG 2 B NAG 2 n 
D 3 NAG 1 C NAG 1 C NAG 1 n 
D 3 NAG 2 C NAG 2 C NAG 2 n 
E 3 NAG 1 D NAG 1 D NAG 1 n 
E 3 NAG 2 D NAG 2 D NAG 2 n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 6PL   ? ? 6PL   ? ? 'SUBJECT OF INVESTIGATION' ? 
2 A1AVC ? ? A1AVC ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
F 4 A1AVC 1 801 801 A1AVC KH2 A . 
G 5 6PL   1 802 802 6PL   6PL A . 
H 5 6PL   1 803 803 6PL   6PL A . 
I 6 NAG   1 804 13  NAG   NAG A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 N 1 C NAG 1   ? O1  ? D NAG 1 O1  
2 1 N 1 A 6PL 802 ? C26 ? G 6PL 1 C26 
3 1 N 1 A 6PL 802 ? C25 ? G 6PL 1 C25 
4 1 N 1 A 6PL 802 ? C24 ? G 6PL 1 C24 
5 1 N 1 A 6PL 802 ? C23 ? G 6PL 1 C23 
6 1 N 1 A 6PL 802 ? C47 ? G 6PL 1 C47 
7 1 N 1 A 6PL 802 ? C48 ? G 6PL 1 C48 
8 1 N 1 A 6PL 803 ? C47 ? H 6PL 1 C47 
9 1 N 1 A 6PL 803 ? C48 ? H 6PL 1 C48 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BVM 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BVM 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BVM 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9BVM 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004  ? 6402 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.665  ? 8671 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 11.222 ? 2513 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.039  ? 935  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.006  ? 1075 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9BVM 
_struct.title                        
'Vitamin K-dependent gamma-carboxylase with protein C propeptide and glutamate-rich region and with vitamin K hydroquinone' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BVM 
_struct_keywords.text            
;GGCX, VKGC, Vitamin K, VKCFD, Hemophilia B, Warfarin, Carboxylation, Blood Coagulaton, Calcium homeostasis, Protein C, MEMBRANE PROTEIN, LYASE-SUBSTRATE complex
;
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN,LYASE/SUBSTRATE' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
E N N 3 ? 
F N N 4 ? 
G N N 5 ? 
H N N 5 ? 
I N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP VKGC_HUMAN P38435 ? 1 
;GPRQDSRIGKLLGFEWTDLSSWRRLVTLLNRPTDPASLAVFRFLFGFLMVLDIPQERGLSSLDRKYLDGLDVCRFPLLDA
LRPLPLDWMYLVYTIMFLGALGMMLGLCYRISCVLFLLPYWYVFLLDKTSWNNHSYLYGLLAFQLTFMDANHYWSVDGLL
NAHRRNAHVPLWNYAVLRGQIFIVYFIAGVKKLDADWVEGYSMEYLSRHWLFSPFKLLLSEELTSLLVVHWGGLLLDLSA
GFLLFFDVSRSIGLFFVSYFHCMNSQLFSIGMFSYVMLASSPLFCSPEWPRKLVSYCPRRLQQLLPLKAAPQPSVSCVYK
RSRGKSGQKPGLRHQLGAAFTLLYLLEQLFLPYSHFLTQGYNNWTNGLYGYSWDMMVHSRSHQHVKITYRDGRTGELGYL
NPGVFTQSRRWKDHADMLKQYATCLSRLLPKYNVTEPQIYFDIWVSINDRFQQRIFDPRVDIVQAAWSPFQRTSWVQPLL
MDLSPWRAKLQEIKSSLDNHTEVVFIADFPGLHLENFVSEDLGNTSIQLLQGEVTVELVAEQKNQTLREGEKMQLPAGEY
HKVYTTSPSPSCYMYVYVNTTELALEQDLAYLQELKEKVENGSETGPLPPELQPLLEGEVKGGPEPTPLVQTFLRRQQRL
QEIERRRNTPFHERFFRFLLRKLYVFRRSFLMTCISLRNLILGRPSLEQLAQEVTYANLRPFEAVGELNPSNTDSSHSNP
PESNPDPVHSEF
;
27 
2 UNP PROC_HUMAN P04070 ? 2 TPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVD 19 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9BVM A 1 ? 732 ? P38435 27 ? 758 ? 27 758 
2 2 9BVM P 1 ? 70  ? P04070 19 ? 88  ? 19 88  
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 6   ? GLY A 13  ? SER A 32  GLY A 39  1 ? 8  
HELX_P HELX_P2  AA2 GLU A 15  ? SER A 20  ? GLU A 41  SER A 46  5 ? 6  
HELX_P HELX_P3  AA3 SER A 21  ? ASN A 30  ? SER A 47  ASN A 56  1 ? 10 
HELX_P HELX_P4  AA4 PRO A 35  ? ILE A 53  ? PRO A 61  ILE A 79  1 ? 19 
HELX_P HELX_P5  AA5 SER A 61  ? LYS A 65  ? SER A 87  LYS A 91  5 ? 5  
HELX_P HELX_P6  AA6 PRO A 85  ? GLY A 106 ? PRO A 111 GLY A 132 1 ? 22 
HELX_P HELX_P7  AA7 CYS A 108 ? ASP A 127 ? CYS A 134 ASP A 153 1 ? 20 
HELX_P HELX_P8  AA8 ASN A 132 ? THR A 146 ? ASN A 158 THR A 172 1 ? 15 
HELX_P HELX_P9  AA9 SER A 155 ? ASN A 161 ? SER A 181 ASN A 187 1 ? 7  
HELX_P HELX_P10 AB1 ALA A 162 ? ARG A 165 ? ALA A 188 ARG A 191 5 ? 4  
HELX_P HELX_P11 AB2 LEU A 171 ? LYS A 192 ? LEU A 197 LYS A 218 1 ? 22 
HELX_P HELX_P12 AB3 ASP A 194 ? GLU A 199 ? ASP A 220 GLU A 225 1 ? 6  
HELX_P HELX_P13 AB4 TYR A 205 ? LEU A 218 ? TYR A 231 LEU A 244 5 ? 14 
HELX_P HELX_P14 AB5 SER A 220 ? VAL A 228 ? SER A 246 VAL A 254 1 ? 9  
HELX_P HELX_P15 AB6 VAL A 229 ? LEU A 244 ? VAL A 255 LEU A 270 1 ? 16 
HELX_P HELX_P16 AB7 SER A 249 ? PHE A 268 ? SER A 275 PHE A 294 1 ? 20 
HELX_P HELX_P17 AB8 MET A 272 ? SER A 281 ? MET A 298 SER A 307 1 ? 10 
HELX_P HELX_P18 AB9 PRO A 282 ? CYS A 285 ? PRO A 308 CYS A 311 5 ? 4  
HELX_P HELX_P19 AC1 GLU A 288 ? TYR A 296 ? GLU A 314 TYR A 322 1 ? 9  
HELX_P HELX_P20 AC2 PRO A 298 ? GLN A 303 ? PRO A 324 GLN A 329 1 ? 6  
HELX_P HELX_P21 AC3 LEU A 332 ? LEU A 351 ? LEU A 358 LEU A 377 1 ? 20 
HELX_P HELX_P22 AC4 PRO A 352 ? SER A 354 ? PRO A 378 SER A 380 5 ? 3  
HELX_P HELX_P23 AC5 THR A 358 ? ASN A 362 ? THR A 384 ASN A 388 5 ? 5  
HELX_P HELX_P24 AC6 ARG A 409 ? ASP A 413 ? ARG A 435 ASP A 439 5 ? 5  
HELX_P HELX_P25 AC7 HIS A 414 ? LEU A 429 ? HIS A 440 LEU A 455 1 ? 16 
HELX_P HELX_P26 AC8 PRO A 430 ? ASN A 433 ? PRO A 456 ASN A 459 5 ? 4  
HELX_P HELX_P27 AC9 LEU A 480 ? SER A 484 ? LEU A 506 SER A 510 5 ? 5  
HELX_P HELX_P28 AD1 PRO A 485 ? SER A 495 ? PRO A 511 SER A 521 1 ? 11 
HELX_P HELX_P29 AD2 ASN A 579 ? ASN A 601 ? ASN A 605 ASN A 627 1 ? 23 
HELX_P HELX_P30 AD3 GLU A 611 ? GLY A 618 ? GLU A 637 GLY A 644 1 ? 8  
HELX_P HELX_P31 AD4 THR A 627 ? ASN A 648 ? THR A 653 ASN A 674 1 ? 22 
HELX_P HELX_P32 AD5 PRO A 650 ? GLY A 683 ? PRO A 676 GLY A 709 1 ? 34 
HELX_P HELX_P33 AD6 SER A 686 ? ASN A 698 ? SER A 712 ASN A 724 1 ? 13 
HELX_P HELX_P34 AD7 SER B 11  ? HIS B 16  ? SER P 29  HIS P 34  1 ? 6  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 73  SG  ? ? ? 1_555 A CYS 424 SG ? ? A CYS 99  A CYS 450 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
covale1 covale one  ? A ASN 433 ND2 ? ? ? 1_555 I NAG .   C1 ? ? A ASN 459 A NAG 804 1_555 ? ? ? ? ? ? ? 1.502 ? N-Glycosylation 
covale2 covale one  ? A ASN 544 ND2 ? ? ? 1_555 C NAG .   C1 ? ? A ASN 570 B NAG 1   1_555 ? ? ? ? ? ? ? 1.442 ? N-Glycosylation 
covale3 covale one  ? A ASN 579 ND2 ? ? ? 1_555 E NAG .   C1 ? ? A ASN 605 D NAG 1   1_555 ? ? ? ? ? ? ? 1.439 ? N-Glycosylation 
covale4 covale both ? C NAG .   O4  ? ? ? 1_555 C NAG .   C1 ? ? B NAG 1   B NAG 2   1_555 ? ? ? ? ? ? ? 1.441 ? ?               
covale5 covale both ? D NAG .   O4  ? ? ? 1_555 D NAG .   C1 ? ? C NAG 1   C NAG 2   1_555 ? ? ? ? ? ? ? 1.173 ? ?               
covale6 covale both ? E NAG .   O4  ? ? ? 1_555 E NAG .   C1 ? ? D NAG 1   D NAG 2   1_555 ? ? ? ? ? ? ? 1.440 ? ?               
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NAG C .  ? ASN A 544 ? NAG B 1   ? 1_555 ASN A 570 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2 NAG E .  ? ASN A 579 ? NAG D 1   ? 1_555 ASN A 605 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3 NAG I .  ? ASN A 433 ? NAG A 804 ? 1_555 ASN A 459 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4 CYS A 73 ? CYS A 424 ? CYS A 99  ? 1_555 CYS A 450 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 453 ? ARG A 454 ? GLN A 479 ARG A 480 
AA1 2 GLN A 438 ? ILE A 447 ? GLN A 464 ILE A 473 
AA1 3 ARG A 380 ? ARG A 390 ? ARG A 406 ARG A 416 
AA1 4 LEU A 397 ? LEU A 400 ? LEU A 423 LEU A 426 
AA1 5 PHE B 9   ? SER B 10  ? PHE P 27  SER P 28  
AA2 1 GLU A 502 ? ASP A 508 ? GLU A 528 ASP A 534 
AA2 2 SER A 571 ? TYR A 577 ? SER A 597 TYR A 603 
AA2 3 THR A 525 ? GLN A 531 ? THR A 551 GLN A 557 
AA2 4 LYS A 552 ? LEU A 555 ? LYS A 578 LEU A 581 
AA3 1 HIS A 513 ? PHE A 517 ? HIS A 539 PHE A 543 
AA3 2 TYR A 560 ? THR A 565 ? TYR A 586 THR A 591 
AA3 3 VAL A 534 ? LEU A 538 ? VAL A 560 LEU A 564 
AA3 4 LYS A 543 ? LEU A 547 ? LYS A 569 LEU A 573 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O GLN A 453 ? O GLN A 479 N VAL A 445 ? N VAL A 471 
AA1 2 3 O TYR A 440 ? O TYR A 466 N THR A 388 ? N THR A 414 
AA1 3 4 N TYR A 389 ? N TYR A 415 O GLY A 398 ? O GLY A 424 
AA1 4 5 N TYR A 399 ? N TYR A 425 O SER B 10  ? O SER P 28  
AA2 1 2 N ILE A 506 ? N ILE A 532 O TYR A 573 ? O TYR A 599 
AA2 2 3 O VAL A 576 ? O VAL A 602 N SER A 526 ? N SER A 552 
AA2 3 4 N ILE A 527 ? N ILE A 553 O MET A 553 ? O MET A 579 
AA3 1 2 N ASN A 516 ? N ASN A 542 O HIS A 561 ? O HIS A 587 
AA3 2 3 O LYS A 562 ? O LYS A 588 N GLU A 537 ? N GLU A 563 
AA3 3 4 N LEU A 538 ? N LEU A 564 O LYS A 543 ? O LYS A 569 
# 
_pdbx_entry_details.entry_id                   9BVM 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 ND2 A ASN 459 ? ? O5 A NAG 804 ? ? 1.69 
2 1 ND2 A ASN 605 ? ? O5 D NAG 1   ? ? 1.72 
3 1 O4  C NAG 1   ? ? O5 C NAG 2   ? ? 1.83 
4 1 ND2 A ASN 550 ? ? C1 C NAG 1   ? ? 1.88 
5 1 O4  B NAG 1   ? ? O5 B NAG 2   ? ? 1.95 
6 1 O4  D NAG 1   ? ? O5 D NAG 2   ? ? 2.00 
7 1 C4  C NAG 1   ? ? C1 C NAG 2   ? ? 2.12 
8 1 ND2 A ASN 459 ? ? C2 A NAG 804 ? ? 2.19 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 HIS A 256 ? ? -93.24  -60.97  
2 1 ASN A 389 ? ? -148.60 -157.95 
3 1 THR A 461 ? ? -78.36  -166.93 
4 1 GLU A 462 ? ? -55.69  106.11  
5 1 HIS P 34  ? ? -92.11  52.70   
6 1 LEU P 50  ? ? 60.25   -135.23 
7 1 HIS P 52  ? ? 63.47   -128.00 
8 1 SER P 54  ? ? 65.78   -103.57 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9BVM 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      OTHER 
# 
_em_3d_reconstruction.entry_id                    9BVM 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.4 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               177459 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
'Vitamin K-dependent gamma-carboxylase with protein C propeptide and glutamate-rich region and with vitamin K hydroquinone' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_image_scans.entry_id                9BVM 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        5760 
_em_image_scans.dimension_width         4092 
_em_image_scans.frames_per_image        ? 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        9BVM 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           130000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   63 
_em_imaging.recording_temperature_maximum   77 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            50.0 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9BVM 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              95 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   283.15 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9BVM 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY 27  ? A GLY 1   
2  1 Y 1 A PRO 28  ? A PRO 2   
3  1 Y 1 A ARG 29  ? A ARG 3   
4  1 Y 1 A GLN 30  ? A GLN 4   
5  1 Y 1 A SER 348 ? A SER 322 
6  1 Y 1 A ARG 349 ? A ARG 323 
7  1 Y 1 A GLY 350 ? A GLY 324 
8  1 Y 1 A LYS 351 ? A LYS 325 
9  1 Y 1 A SER 352 ? A SER 326 
10 1 Y 1 A GLU 729 ? A GLU 703 
11 1 Y 1 A ALA 730 ? A ALA 704 
12 1 Y 1 A VAL 731 ? A VAL 705 
13 1 Y 1 A GLY 732 ? A GLY 706 
14 1 Y 1 A GLU 733 ? A GLU 707 
15 1 Y 1 A LEU 734 ? A LEU 708 
16 1 Y 1 A ASN 735 ? A ASN 709 
17 1 Y 1 A PRO 736 ? A PRO 710 
18 1 Y 1 A SER 737 ? A SER 711 
19 1 Y 1 A ASN 738 ? A ASN 712 
20 1 Y 1 A THR 739 ? A THR 713 
21 1 Y 1 A ASP 740 ? A ASP 714 
22 1 Y 1 A SER 741 ? A SER 715 
23 1 Y 1 A SER 742 ? A SER 716 
24 1 Y 1 A HIS 743 ? A HIS 717 
25 1 Y 1 A SER 744 ? A SER 718 
26 1 Y 1 A ASN 745 ? A ASN 719 
27 1 Y 1 A PRO 746 ? A PRO 720 
28 1 Y 1 A PRO 747 ? A PRO 721 
29 1 Y 1 A GLU 748 ? A GLU 722 
30 1 Y 1 A SER 749 ? A SER 723 
31 1 Y 1 A ASN 750 ? A ASN 724 
32 1 Y 1 A PRO 751 ? A PRO 725 
33 1 Y 1 A ASP 752 ? A ASP 726 
34 1 Y 1 A PRO 753 ? A PRO 727 
35 1 Y 1 A VAL 754 ? A VAL 728 
36 1 Y 1 A HIS 755 ? A HIS 729 
37 1 Y 1 A SER 756 ? A SER 730 
38 1 Y 1 A GLU 757 ? A GLU 731 
39 1 Y 1 A PHE 758 ? A PHE 732 
40 1 Y 1 P THR 19  ? B THR 1   
41 1 Y 1 P PRO 20  ? B PRO 2   
42 1 Y 1 P ALA 21  ? B ALA 3   
43 1 Y 1 P PRO 22  ? B PRO 4   
44 1 Y 1 P GLU 58  ? B GLU 40  
45 1 Y 1 P CYS 59  ? B CYS 41  
46 1 Y 1 P ILE 60  ? B ILE 42  
47 1 Y 1 P GLU 61  ? B GLU 43  
48 1 Y 1 P GLU 62  ? B GLU 44  
49 1 Y 1 P ILE 63  ? B ILE 45  
50 1 Y 1 P CYS 64  ? B CYS 46  
51 1 Y 1 P ASP 65  ? B ASP 47  
52 1 Y 1 P PHE 66  ? B PHE 48  
53 1 Y 1 P GLU 67  ? B GLU 49  
54 1 Y 1 P GLU 68  ? B GLU 50  
55 1 Y 1 P ALA 69  ? B ALA 51  
56 1 Y 1 P LYS 70  ? B LYS 52  
57 1 Y 1 P GLU 71  ? B GLU 53  
58 1 Y 1 P ILE 72  ? B ILE 54  
59 1 Y 1 P PHE 73  ? B PHE 55  
60 1 Y 1 P GLN 74  ? B GLN 56  
61 1 Y 1 P ASN 75  ? B ASN 57  
62 1 Y 1 P VAL 76  ? B VAL 58  
63 1 Y 1 P ASP 77  ? B ASP 59  
64 1 Y 1 P ASP 78  ? B ASP 60  
65 1 Y 1 P THR 79  ? B THR 61  
66 1 Y 1 P LEU 80  ? B LEU 62  
67 1 Y 1 P ALA 81  ? B ALA 63  
68 1 Y 1 P PHE 82  ? B PHE 64  
69 1 Y 1 P TRP 83  ? B TRP 65  
70 1 Y 1 P SER 84  ? B SER 66  
71 1 Y 1 P LYS 85  ? B LYS 67  
72 1 Y 1 P HIS 86  ? B HIS 68  
73 1 Y 1 P VAL 87  ? B VAL 69  
74 1 Y 1 P ASP 88  ? B ASP 70  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
6PL   C26  C N N 1   
6PL   C25  C N N 2   
6PL   C24  C N N 3   
6PL   C23  C N N 4   
6PL   C22  C N N 5   
6PL   C21  C N N 6   
6PL   C20  C N N 7   
6PL   C19  C N N 8   
6PL   C18  C N N 9   
6PL   C17  C N N 10  
6PL   C16  C N N 11  
6PL   C15  C N N 12  
6PL   C14  C N N 13  
6PL   C13  C N N 14  
6PL   C12  C N N 15  
6PL   C11  C N N 16  
6PL   O11  O N N 17  
6PL   O3   O N N 18  
6PL   C3   C N N 19  
6PL   C2   C N R 20  
6PL   C1   C N N 21  
6PL   O3P  O N N 22  
6PL   P    P N S 23  
6PL   O1P  O N N 24  
6PL   O2P  O N N 25  
6PL   O4P  O N N 26  
6PL   C4   C N N 27  
6PL   C5   C N N 28  
6PL   N    N N N 29  
6PL   C7   C N N 30  
6PL   C8   C N N 31  
6PL   C6   C N N 32  
6PL   O2   O N N 33  
6PL   C31  C N N 34  
6PL   O31  O N N 35  
6PL   C32  C N N 36  
6PL   C33  C N N 37  
6PL   C34  C N N 38  
6PL   C35  C N N 39  
6PL   C36  C N N 40  
6PL   C37  C N N 41  
6PL   C38  C N N 42  
6PL   C39  C N N 43  
6PL   C40  C N N 44  
6PL   C41  C N N 45  
6PL   C42  C N N 46  
6PL   C43  C N N 47  
6PL   C44  C N N 48  
6PL   C45  C N N 49  
6PL   C46  C N N 50  
6PL   C47  C N N 51  
6PL   C48  C N N 52  
6PL   H261 H N N 53  
6PL   H262 H N N 54  
6PL   H263 H N N 55  
6PL   H251 H N N 56  
6PL   H252 H N N 57  
6PL   H241 H N N 58  
6PL   H242 H N N 59  
6PL   H231 H N N 60  
6PL   H232 H N N 61  
6PL   H221 H N N 62  
6PL   H222 H N N 63  
6PL   H211 H N N 64  
6PL   H212 H N N 65  
6PL   H201 H N N 66  
6PL   H202 H N N 67  
6PL   H191 H N N 68  
6PL   H192 H N N 69  
6PL   H181 H N N 70  
6PL   H182 H N N 71  
6PL   H171 H N N 72  
6PL   H172 H N N 73  
6PL   H161 H N N 74  
6PL   H162 H N N 75  
6PL   H151 H N N 76  
6PL   H152 H N N 77  
6PL   H141 H N N 78  
6PL   H142 H N N 79  
6PL   H131 H N N 80  
6PL   H132 H N N 81  
6PL   H121 H N N 82  
6PL   H122 H N N 83  
6PL   H31  H N N 84  
6PL   H32  H N N 85  
6PL   H2   H N N 86  
6PL   H11  H N N 87  
6PL   H12  H N N 88  
6PL   H2P  H N N 89  
6PL   H41  H N N 90  
6PL   H42  H N N 91  
6PL   H51  H N N 92  
6PL   H52  H N N 93  
6PL   H71  H N N 94  
6PL   H72  H N N 95  
6PL   H73  H N N 96  
6PL   H81  H N N 97  
6PL   H82  H N N 98  
6PL   H83  H N N 99  
6PL   H61  H N N 100 
6PL   H62  H N N 101 
6PL   H63  H N N 102 
6PL   H321 H N N 103 
6PL   H322 H N N 104 
6PL   H331 H N N 105 
6PL   H332 H N N 106 
6PL   H341 H N N 107 
6PL   H342 H N N 108 
6PL   H351 H N N 109 
6PL   H352 H N N 110 
6PL   H361 H N N 111 
6PL   H362 H N N 112 
6PL   H371 H N N 113 
6PL   H372 H N N 114 
6PL   H381 H N N 115 
6PL   H382 H N N 116 
6PL   H391 H N N 117 
6PL   H392 H N N 118 
6PL   H401 H N N 119 
6PL   H402 H N N 120 
6PL   H411 H N N 121 
6PL   H412 H N N 122 
6PL   H421 H N N 123 
6PL   H422 H N N 124 
6PL   H431 H N N 125 
6PL   H432 H N N 126 
6PL   H441 H N N 127 
6PL   H442 H N N 128 
6PL   H451 H N N 129 
6PL   H452 H N N 130 
6PL   H461 H N N 131 
6PL   H462 H N N 132 
6PL   H471 H N N 133 
6PL   H472 H N N 134 
6PL   H481 H N N 135 
6PL   H482 H N N 136 
6PL   H483 H N N 137 
A1AVC C11  C Y N 138 
A1AVC C12  C N N 139 
A1AVC C13  C N N 140 
A1AVC C14  C N N 141 
A1AVC C15  C N N 142 
A1AVC C16  C N N 143 
A1AVC C01  C N N 144 
A1AVC C02  C Y N 145 
A1AVC C03  C Y N 146 
A1AVC C04  C Y N 147 
A1AVC C05  C Y N 148 
A1AVC C06  C Y N 149 
A1AVC C07  C Y N 150 
A1AVC C08  C Y N 151 
A1AVC C09  C Y N 152 
A1AVC C10  C Y N 153 
A1AVC C17  C N N 154 
A1AVC C18  C N N 155 
A1AVC C19  C N R 156 
A1AVC C20  C N N 157 
A1AVC C21  C N N 158 
A1AVC C22  C N N 159 
A1AVC C23  C N N 160 
A1AVC C24  C N R 161 
A1AVC C25  C N N 162 
A1AVC C26  C N N 163 
A1AVC C27  C N N 164 
A1AVC C28  C N N 165 
A1AVC C29  C N N 166 
A1AVC C30  C N N 167 
A1AVC C31  C N N 168 
A1AVC O32  O N N 169 
A1AVC O33  O N N 170 
A1AVC H1   H N N 171 
A1AVC H2   H N N 172 
A1AVC H3   H N N 173 
A1AVC H4   H N N 174 
A1AVC H5   H N N 175 
A1AVC H6   H N N 176 
A1AVC H7   H N N 177 
A1AVC H8   H N N 178 
A1AVC H9   H N N 179 
A1AVC H10  H N N 180 
A1AVC H11  H N N 181 
A1AVC H12  H N N 182 
A1AVC H13  H N N 183 
A1AVC H14  H N N 184 
A1AVC H15  H N N 185 
A1AVC H16  H N N 186 
A1AVC H17  H N N 187 
A1AVC H18  H N N 188 
A1AVC H19  H N N 189 
A1AVC H20  H N N 190 
A1AVC H21  H N N 191 
A1AVC H22  H N N 192 
A1AVC H23  H N N 193 
A1AVC H24  H N N 194 
A1AVC H25  H N N 195 
A1AVC H26  H N N 196 
A1AVC H27  H N N 197 
A1AVC H28  H N N 198 
A1AVC H29  H N N 199 
A1AVC H30  H N N 200 
A1AVC H31  H N N 201 
A1AVC H32  H N N 202 
A1AVC H33  H N N 203 
A1AVC H34  H N N 204 
A1AVC H35  H N N 205 
A1AVC H36  H N N 206 
A1AVC H37  H N N 207 
A1AVC H38  H N N 208 
A1AVC H39  H N N 209 
A1AVC H40  H N N 210 
A1AVC H41  H N N 211 
A1AVC H42  H N N 212 
A1AVC H43  H N N 213 
A1AVC H44  H N N 214 
A1AVC H45  H N N 215 
A1AVC H46  H N N 216 
A1AVC H47  H N N 217 
A1AVC H48  H N N 218 
ALA   N    N N N 219 
ALA   CA   C N S 220 
ALA   C    C N N 221 
ALA   O    O N N 222 
ALA   CB   C N N 223 
ALA   OXT  O N N 224 
ALA   H    H N N 225 
ALA   H2   H N N 226 
ALA   HA   H N N 227 
ALA   HB1  H N N 228 
ALA   HB2  H N N 229 
ALA   HB3  H N N 230 
ALA   HXT  H N N 231 
ARG   N    N N N 232 
ARG   CA   C N S 233 
ARG   C    C N N 234 
ARG   O    O N N 235 
ARG   CB   C N N 236 
ARG   CG   C N N 237 
ARG   CD   C N N 238 
ARG   NE   N N N 239 
ARG   CZ   C N N 240 
ARG   NH1  N N N 241 
ARG   NH2  N N N 242 
ARG   OXT  O N N 243 
ARG   H    H N N 244 
ARG   H2   H N N 245 
ARG   HA   H N N 246 
ARG   HB2  H N N 247 
ARG   HB3  H N N 248 
ARG   HG2  H N N 249 
ARG   HG3  H N N 250 
ARG   HD2  H N N 251 
ARG   HD3  H N N 252 
ARG   HE   H N N 253 
ARG   HH11 H N N 254 
ARG   HH12 H N N 255 
ARG   HH21 H N N 256 
ARG   HH22 H N N 257 
ARG   HXT  H N N 258 
ASN   N    N N N 259 
ASN   CA   C N S 260 
ASN   C    C N N 261 
ASN   O    O N N 262 
ASN   CB   C N N 263 
ASN   CG   C N N 264 
ASN   OD1  O N N 265 
ASN   ND2  N N N 266 
ASN   OXT  O N N 267 
ASN   H    H N N 268 
ASN   H2   H N N 269 
ASN   HA   H N N 270 
ASN   HB2  H N N 271 
ASN   HB3  H N N 272 
ASN   HD21 H N N 273 
ASN   HD22 H N N 274 
ASN   HXT  H N N 275 
ASP   N    N N N 276 
ASP   CA   C N S 277 
ASP   C    C N N 278 
ASP   O    O N N 279 
ASP   CB   C N N 280 
ASP   CG   C N N 281 
ASP   OD1  O N N 282 
ASP   OD2  O N N 283 
ASP   OXT  O N N 284 
ASP   H    H N N 285 
ASP   H2   H N N 286 
ASP   HA   H N N 287 
ASP   HB2  H N N 288 
ASP   HB3  H N N 289 
ASP   HD2  H N N 290 
ASP   HXT  H N N 291 
CYS   N    N N N 292 
CYS   CA   C N R 293 
CYS   C    C N N 294 
CYS   O    O N N 295 
CYS   CB   C N N 296 
CYS   SG   S N N 297 
CYS   OXT  O N N 298 
CYS   H    H N N 299 
CYS   H2   H N N 300 
CYS   HA   H N N 301 
CYS   HB2  H N N 302 
CYS   HB3  H N N 303 
CYS   HG   H N N 304 
CYS   HXT  H N N 305 
GLN   N    N N N 306 
GLN   CA   C N S 307 
GLN   C    C N N 308 
GLN   O    O N N 309 
GLN   CB   C N N 310 
GLN   CG   C N N 311 
GLN   CD   C N N 312 
GLN   OE1  O N N 313 
GLN   NE2  N N N 314 
GLN   OXT  O N N 315 
GLN   H    H N N 316 
GLN   H2   H N N 317 
GLN   HA   H N N 318 
GLN   HB2  H N N 319 
GLN   HB3  H N N 320 
GLN   HG2  H N N 321 
GLN   HG3  H N N 322 
GLN   HE21 H N N 323 
GLN   HE22 H N N 324 
GLN   HXT  H N N 325 
GLU   N    N N N 326 
GLU   CA   C N S 327 
GLU   C    C N N 328 
GLU   O    O N N 329 
GLU   CB   C N N 330 
GLU   CG   C N N 331 
GLU   CD   C N N 332 
GLU   OE1  O N N 333 
GLU   OE2  O N N 334 
GLU   OXT  O N N 335 
GLU   H    H N N 336 
GLU   H2   H N N 337 
GLU   HA   H N N 338 
GLU   HB2  H N N 339 
GLU   HB3  H N N 340 
GLU   HG2  H N N 341 
GLU   HG3  H N N 342 
GLU   HE2  H N N 343 
GLU   HXT  H N N 344 
GLY   N    N N N 345 
GLY   CA   C N N 346 
GLY   C    C N N 347 
GLY   O    O N N 348 
GLY   OXT  O N N 349 
GLY   H    H N N 350 
GLY   H2   H N N 351 
GLY   HA2  H N N 352 
GLY   HA3  H N N 353 
GLY   HXT  H N N 354 
HIS   N    N N N 355 
HIS   CA   C N S 356 
HIS   C    C N N 357 
HIS   O    O N N 358 
HIS   CB   C N N 359 
HIS   CG   C Y N 360 
HIS   ND1  N Y N 361 
HIS   CD2  C Y N 362 
HIS   CE1  C Y N 363 
HIS   NE2  N Y N 364 
HIS   OXT  O N N 365 
HIS   H    H N N 366 
HIS   H2   H N N 367 
HIS   HA   H N N 368 
HIS   HB2  H N N 369 
HIS   HB3  H N N 370 
HIS   HD1  H N N 371 
HIS   HD2  H N N 372 
HIS   HE1  H N N 373 
HIS   HE2  H N N 374 
HIS   HXT  H N N 375 
ILE   N    N N N 376 
ILE   CA   C N S 377 
ILE   C    C N N 378 
ILE   O    O N N 379 
ILE   CB   C N S 380 
ILE   CG1  C N N 381 
ILE   CG2  C N N 382 
ILE   CD1  C N N 383 
ILE   OXT  O N N 384 
ILE   H    H N N 385 
ILE   H2   H N N 386 
ILE   HA   H N N 387 
ILE   HB   H N N 388 
ILE   HG12 H N N 389 
ILE   HG13 H N N 390 
ILE   HG21 H N N 391 
ILE   HG22 H N N 392 
ILE   HG23 H N N 393 
ILE   HD11 H N N 394 
ILE   HD12 H N N 395 
ILE   HD13 H N N 396 
ILE   HXT  H N N 397 
LEU   N    N N N 398 
LEU   CA   C N S 399 
LEU   C    C N N 400 
LEU   O    O N N 401 
LEU   CB   C N N 402 
LEU   CG   C N N 403 
LEU   CD1  C N N 404 
LEU   CD2  C N N 405 
LEU   OXT  O N N 406 
LEU   H    H N N 407 
LEU   H2   H N N 408 
LEU   HA   H N N 409 
LEU   HB2  H N N 410 
LEU   HB3  H N N 411 
LEU   HG   H N N 412 
LEU   HD11 H N N 413 
LEU   HD12 H N N 414 
LEU   HD13 H N N 415 
LEU   HD21 H N N 416 
LEU   HD22 H N N 417 
LEU   HD23 H N N 418 
LEU   HXT  H N N 419 
LYS   N    N N N 420 
LYS   CA   C N S 421 
LYS   C    C N N 422 
LYS   O    O N N 423 
LYS   CB   C N N 424 
LYS   CG   C N N 425 
LYS   CD   C N N 426 
LYS   CE   C N N 427 
LYS   NZ   N N N 428 
LYS   OXT  O N N 429 
LYS   H    H N N 430 
LYS   H2   H N N 431 
LYS   HA   H N N 432 
LYS   HB2  H N N 433 
LYS   HB3  H N N 434 
LYS   HG2  H N N 435 
LYS   HG3  H N N 436 
LYS   HD2  H N N 437 
LYS   HD3  H N N 438 
LYS   HE2  H N N 439 
LYS   HE3  H N N 440 
LYS   HZ1  H N N 441 
LYS   HZ2  H N N 442 
LYS   HZ3  H N N 443 
LYS   HXT  H N N 444 
MET   N    N N N 445 
MET   CA   C N S 446 
MET   C    C N N 447 
MET   O    O N N 448 
MET   CB   C N N 449 
MET   CG   C N N 450 
MET   SD   S N N 451 
MET   CE   C N N 452 
MET   OXT  O N N 453 
MET   H    H N N 454 
MET   H2   H N N 455 
MET   HA   H N N 456 
MET   HB2  H N N 457 
MET   HB3  H N N 458 
MET   HG2  H N N 459 
MET   HG3  H N N 460 
MET   HE1  H N N 461 
MET   HE2  H N N 462 
MET   HE3  H N N 463 
MET   HXT  H N N 464 
NAG   C1   C N R 465 
NAG   C2   C N R 466 
NAG   C3   C N R 467 
NAG   C4   C N S 468 
NAG   C5   C N R 469 
NAG   C6   C N N 470 
NAG   C7   C N N 471 
NAG   C8   C N N 472 
NAG   N2   N N N 473 
NAG   O1   O N N 474 
NAG   O3   O N N 475 
NAG   O4   O N N 476 
NAG   O5   O N N 477 
NAG   O6   O N N 478 
NAG   O7   O N N 479 
NAG   H1   H N N 480 
NAG   H2   H N N 481 
NAG   H3   H N N 482 
NAG   H4   H N N 483 
NAG   H5   H N N 484 
NAG   H61  H N N 485 
NAG   H62  H N N 486 
NAG   H81  H N N 487 
NAG   H82  H N N 488 
NAG   H83  H N N 489 
NAG   HN2  H N N 490 
NAG   HO1  H N N 491 
NAG   HO3  H N N 492 
NAG   HO4  H N N 493 
NAG   HO6  H N N 494 
PHE   N    N N N 495 
PHE   CA   C N S 496 
PHE   C    C N N 497 
PHE   O    O N N 498 
PHE   CB   C N N 499 
PHE   CG   C Y N 500 
PHE   CD1  C Y N 501 
PHE   CD2  C Y N 502 
PHE   CE1  C Y N 503 
PHE   CE2  C Y N 504 
PHE   CZ   C Y N 505 
PHE   OXT  O N N 506 
PHE   H    H N N 507 
PHE   H2   H N N 508 
PHE   HA   H N N 509 
PHE   HB2  H N N 510 
PHE   HB3  H N N 511 
PHE   HD1  H N N 512 
PHE   HD2  H N N 513 
PHE   HE1  H N N 514 
PHE   HE2  H N N 515 
PHE   HZ   H N N 516 
PHE   HXT  H N N 517 
PRO   N    N N N 518 
PRO   CA   C N S 519 
PRO   C    C N N 520 
PRO   O    O N N 521 
PRO   CB   C N N 522 
PRO   CG   C N N 523 
PRO   CD   C N N 524 
PRO   OXT  O N N 525 
PRO   H    H N N 526 
PRO   HA   H N N 527 
PRO   HB2  H N N 528 
PRO   HB3  H N N 529 
PRO   HG2  H N N 530 
PRO   HG3  H N N 531 
PRO   HD2  H N N 532 
PRO   HD3  H N N 533 
PRO   HXT  H N N 534 
SER   N    N N N 535 
SER   CA   C N S 536 
SER   C    C N N 537 
SER   O    O N N 538 
SER   CB   C N N 539 
SER   OG   O N N 540 
SER   OXT  O N N 541 
SER   H    H N N 542 
SER   H2   H N N 543 
SER   HA   H N N 544 
SER   HB2  H N N 545 
SER   HB3  H N N 546 
SER   HG   H N N 547 
SER   HXT  H N N 548 
THR   N    N N N 549 
THR   CA   C N S 550 
THR   C    C N N 551 
THR   O    O N N 552 
THR   CB   C N R 553 
THR   OG1  O N N 554 
THR   CG2  C N N 555 
THR   OXT  O N N 556 
THR   H    H N N 557 
THR   H2   H N N 558 
THR   HA   H N N 559 
THR   HB   H N N 560 
THR   HG1  H N N 561 
THR   HG21 H N N 562 
THR   HG22 H N N 563 
THR   HG23 H N N 564 
THR   HXT  H N N 565 
TRP   N    N N N 566 
TRP   CA   C N S 567 
TRP   C    C N N 568 
TRP   O    O N N 569 
TRP   CB   C N N 570 
TRP   CG   C Y N 571 
TRP   CD1  C Y N 572 
TRP   CD2  C Y N 573 
TRP   NE1  N Y N 574 
TRP   CE2  C Y N 575 
TRP   CE3  C Y N 576 
TRP   CZ2  C Y N 577 
TRP   CZ3  C Y N 578 
TRP   CH2  C Y N 579 
TRP   OXT  O N N 580 
TRP   H    H N N 581 
TRP   H2   H N N 582 
TRP   HA   H N N 583 
TRP   HB2  H N N 584 
TRP   HB3  H N N 585 
TRP   HD1  H N N 586 
TRP   HE1  H N N 587 
TRP   HE3  H N N 588 
TRP   HZ2  H N N 589 
TRP   HZ3  H N N 590 
TRP   HH2  H N N 591 
TRP   HXT  H N N 592 
TYR   N    N N N 593 
TYR   CA   C N S 594 
TYR   C    C N N 595 
TYR   O    O N N 596 
TYR   CB   C N N 597 
TYR   CG   C Y N 598 
TYR   CD1  C Y N 599 
TYR   CD2  C Y N 600 
TYR   CE1  C Y N 601 
TYR   CE2  C Y N 602 
TYR   CZ   C Y N 603 
TYR   OH   O N N 604 
TYR   OXT  O N N 605 
TYR   H    H N N 606 
TYR   H2   H N N 607 
TYR   HA   H N N 608 
TYR   HB2  H N N 609 
TYR   HB3  H N N 610 
TYR   HD1  H N N 611 
TYR   HD2  H N N 612 
TYR   HE1  H N N 613 
TYR   HE2  H N N 614 
TYR   HH   H N N 615 
TYR   HXT  H N N 616 
VAL   N    N N N 617 
VAL   CA   C N S 618 
VAL   C    C N N 619 
VAL   O    O N N 620 
VAL   CB   C N N 621 
VAL   CG1  C N N 622 
VAL   CG2  C N N 623 
VAL   OXT  O N N 624 
VAL   H    H N N 625 
VAL   H2   H N N 626 
VAL   HA   H N N 627 
VAL   HB   H N N 628 
VAL   HG11 H N N 629 
VAL   HG12 H N N 630 
VAL   HG13 H N N 631 
VAL   HG21 H N N 632 
VAL   HG22 H N N 633 
VAL   HG23 H N N 634 
VAL   HXT  H N N 635 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
6PL   C26 C25  sing N N 1   
6PL   C26 H261 sing N N 2   
6PL   C26 H262 sing N N 3   
6PL   C26 H263 sing N N 4   
6PL   C25 C24  sing N N 5   
6PL   C25 H251 sing N N 6   
6PL   C25 H252 sing N N 7   
6PL   C24 C23  sing N N 8   
6PL   C24 H241 sing N N 9   
6PL   C24 H242 sing N N 10  
6PL   C23 C22  sing N N 11  
6PL   C23 H231 sing N N 12  
6PL   C23 H232 sing N N 13  
6PL   C22 C21  sing N N 14  
6PL   C22 H221 sing N N 15  
6PL   C22 H222 sing N N 16  
6PL   C21 C20  sing N N 17  
6PL   C21 H211 sing N N 18  
6PL   C21 H212 sing N N 19  
6PL   C20 C19  sing N N 20  
6PL   C20 H201 sing N N 21  
6PL   C20 H202 sing N N 22  
6PL   C19 C18  sing N N 23  
6PL   C19 H191 sing N N 24  
6PL   C19 H192 sing N N 25  
6PL   C18 C17  sing N N 26  
6PL   C18 H181 sing N N 27  
6PL   C18 H182 sing N N 28  
6PL   C17 C16  sing N N 29  
6PL   C17 H171 sing N N 30  
6PL   C17 H172 sing N N 31  
6PL   C16 C15  sing N N 32  
6PL   C16 H161 sing N N 33  
6PL   C16 H162 sing N N 34  
6PL   C15 C14  sing N N 35  
6PL   C15 H151 sing N N 36  
6PL   C15 H152 sing N N 37  
6PL   C14 C13  sing N N 38  
6PL   C14 H141 sing N N 39  
6PL   C14 H142 sing N N 40  
6PL   C13 C12  sing N N 41  
6PL   C13 H131 sing N N 42  
6PL   C13 H132 sing N N 43  
6PL   C12 C11  sing N N 44  
6PL   C12 H121 sing N N 45  
6PL   C12 H122 sing N N 46  
6PL   C11 O11  doub N N 47  
6PL   C11 O3   sing N N 48  
6PL   O3  C3   sing N N 49  
6PL   C3  C2   sing N N 50  
6PL   C3  H31  sing N N 51  
6PL   C3  H32  sing N N 52  
6PL   C2  C1   sing N N 53  
6PL   C2  O2   sing N N 54  
6PL   C2  H2   sing N N 55  
6PL   C1  O3P  sing N N 56  
6PL   C1  H11  sing N N 57  
6PL   C1  H12  sing N N 58  
6PL   O3P P    sing N N 59  
6PL   P   O1P  doub N N 60  
6PL   P   O2P  sing N N 61  
6PL   P   O4P  sing N N 62  
6PL   O2P H2P  sing N N 63  
6PL   O4P C4   sing N N 64  
6PL   C4  C5   sing N N 65  
6PL   C4  H41  sing N N 66  
6PL   C4  H42  sing N N 67  
6PL   C5  N    sing N N 68  
6PL   C5  H51  sing N N 69  
6PL   C5  H52  sing N N 70  
6PL   N   C7   sing N N 71  
6PL   N   C8   sing N N 72  
6PL   N   C6   sing N N 73  
6PL   C7  H71  sing N N 74  
6PL   C7  H72  sing N N 75  
6PL   C7  H73  sing N N 76  
6PL   C8  H81  sing N N 77  
6PL   C8  H82  sing N N 78  
6PL   C8  H83  sing N N 79  
6PL   C6  H61  sing N N 80  
6PL   C6  H62  sing N N 81  
6PL   C6  H63  sing N N 82  
6PL   O2  C31  sing N N 83  
6PL   C31 O31  doub N N 84  
6PL   C31 C32  sing N N 85  
6PL   C32 C33  sing N N 86  
6PL   C32 H321 sing N N 87  
6PL   C32 H322 sing N N 88  
6PL   C33 C34  sing N N 89  
6PL   C33 H331 sing N N 90  
6PL   C33 H332 sing N N 91  
6PL   C34 C35  sing N N 92  
6PL   C34 H341 sing N N 93  
6PL   C34 H342 sing N N 94  
6PL   C35 C36  sing N N 95  
6PL   C35 H351 sing N N 96  
6PL   C35 H352 sing N N 97  
6PL   C36 C37  sing N N 98  
6PL   C36 H361 sing N N 99  
6PL   C36 H362 sing N N 100 
6PL   C37 C38  sing N N 101 
6PL   C37 H371 sing N N 102 
6PL   C37 H372 sing N N 103 
6PL   C38 C39  sing N N 104 
6PL   C38 H381 sing N N 105 
6PL   C38 H382 sing N N 106 
6PL   C39 C40  sing N N 107 
6PL   C39 H391 sing N N 108 
6PL   C39 H392 sing N N 109 
6PL   C40 C41  sing N N 110 
6PL   C40 H401 sing N N 111 
6PL   C40 H402 sing N N 112 
6PL   C41 C42  sing N N 113 
6PL   C41 H411 sing N N 114 
6PL   C41 H412 sing N N 115 
6PL   C42 C43  sing N N 116 
6PL   C42 H421 sing N N 117 
6PL   C42 H422 sing N N 118 
6PL   C43 C44  sing N N 119 
6PL   C43 H431 sing N N 120 
6PL   C43 H432 sing N N 121 
6PL   C44 C45  sing N N 122 
6PL   C44 H441 sing N N 123 
6PL   C44 H442 sing N N 124 
6PL   C45 C46  sing N N 125 
6PL   C45 H451 sing N N 126 
6PL   C45 H452 sing N N 127 
6PL   C46 C47  sing N N 128 
6PL   C46 H461 sing N N 129 
6PL   C46 H462 sing N N 130 
6PL   C47 C48  sing N N 131 
6PL   C47 H471 sing N N 132 
6PL   C47 H472 sing N N 133 
6PL   C48 H481 sing N N 134 
6PL   C48 H482 sing N N 135 
6PL   C48 H483 sing N N 136 
A1AVC C30 C29  sing N N 137 
A1AVC C29 C28  sing N N 138 
A1AVC C29 C31  sing N N 139 
A1AVC C28 C27  sing N N 140 
A1AVC C21 C22  sing N N 141 
A1AVC C21 C19  sing N N 142 
A1AVC C18 C17  sing N N 143 
A1AVC C18 C19  sing N N 144 
A1AVC C16 C17  sing N N 145 
A1AVC C16 C14  sing N N 146 
A1AVC C27 C26  sing N N 147 
A1AVC C15 C14  sing N N 148 
A1AVC C22 C23  sing N N 149 
A1AVC C14 C13  doub N E 150 
A1AVC C19 C20  sing N N 151 
A1AVC C26 C24  sing N N 152 
A1AVC C23 C24  sing N N 153 
A1AVC C13 C12  sing N N 154 
A1AVC C24 C25  sing N N 155 
A1AVC C12 C11  sing N N 156 
A1AVC O32 C10  sing N N 157 
A1AVC C11 C10  doub Y N 158 
A1AVC C11 C02  sing Y N 159 
A1AVC C01 C02  sing N N 160 
A1AVC C10 C09  sing Y N 161 
A1AVC C02 C03  doub Y N 162 
A1AVC C09 C08  sing Y N 163 
A1AVC C09 C04  doub Y N 164 
A1AVC C03 C04  sing Y N 165 
A1AVC C03 O33  sing N N 166 
A1AVC C08 C07  doub Y N 167 
A1AVC C04 C05  sing Y N 168 
A1AVC C07 C06  sing Y N 169 
A1AVC C05 C06  doub Y N 170 
A1AVC C12 H1   sing N N 171 
A1AVC C12 H2   sing N N 172 
A1AVC C13 H3   sing N N 173 
A1AVC C15 H4   sing N N 174 
A1AVC C15 H5   sing N N 175 
A1AVC C15 H6   sing N N 176 
A1AVC C16 H7   sing N N 177 
A1AVC C16 H8   sing N N 178 
A1AVC C01 H9   sing N N 179 
A1AVC C01 H10  sing N N 180 
A1AVC C01 H11  sing N N 181 
A1AVC C05 H12  sing N N 182 
A1AVC C06 H13  sing N N 183 
A1AVC C07 H14  sing N N 184 
A1AVC C08 H15  sing N N 185 
A1AVC C17 H16  sing N N 186 
A1AVC C17 H17  sing N N 187 
A1AVC C18 H18  sing N N 188 
A1AVC C18 H19  sing N N 189 
A1AVC C19 H20  sing N N 190 
A1AVC C20 H21  sing N N 191 
A1AVC C20 H22  sing N N 192 
A1AVC C20 H23  sing N N 193 
A1AVC C21 H24  sing N N 194 
A1AVC C21 H25  sing N N 195 
A1AVC C22 H26  sing N N 196 
A1AVC C22 H27  sing N N 197 
A1AVC C23 H28  sing N N 198 
A1AVC C23 H29  sing N N 199 
A1AVC C24 H30  sing N N 200 
A1AVC C25 H31  sing N N 201 
A1AVC C25 H32  sing N N 202 
A1AVC C25 H33  sing N N 203 
A1AVC C26 H34  sing N N 204 
A1AVC C26 H35  sing N N 205 
A1AVC C27 H36  sing N N 206 
A1AVC C27 H37  sing N N 207 
A1AVC C28 H38  sing N N 208 
A1AVC C28 H39  sing N N 209 
A1AVC C29 H40  sing N N 210 
A1AVC C30 H41  sing N N 211 
A1AVC C30 H42  sing N N 212 
A1AVC C30 H43  sing N N 213 
A1AVC C31 H44  sing N N 214 
A1AVC C31 H45  sing N N 215 
A1AVC C31 H46  sing N N 216 
A1AVC O32 H47  sing N N 217 
A1AVC O33 H48  sing N N 218 
ALA   N   CA   sing N N 219 
ALA   N   H    sing N N 220 
ALA   N   H2   sing N N 221 
ALA   CA  C    sing N N 222 
ALA   CA  CB   sing N N 223 
ALA   CA  HA   sing N N 224 
ALA   C   O    doub N N 225 
ALA   C   OXT  sing N N 226 
ALA   CB  HB1  sing N N 227 
ALA   CB  HB2  sing N N 228 
ALA   CB  HB3  sing N N 229 
ALA   OXT HXT  sing N N 230 
ARG   N   CA   sing N N 231 
ARG   N   H    sing N N 232 
ARG   N   H2   sing N N 233 
ARG   CA  C    sing N N 234 
ARG   CA  CB   sing N N 235 
ARG   CA  HA   sing N N 236 
ARG   C   O    doub N N 237 
ARG   C   OXT  sing N N 238 
ARG   CB  CG   sing N N 239 
ARG   CB  HB2  sing N N 240 
ARG   CB  HB3  sing N N 241 
ARG   CG  CD   sing N N 242 
ARG   CG  HG2  sing N N 243 
ARG   CG  HG3  sing N N 244 
ARG   CD  NE   sing N N 245 
ARG   CD  HD2  sing N N 246 
ARG   CD  HD3  sing N N 247 
ARG   NE  CZ   sing N N 248 
ARG   NE  HE   sing N N 249 
ARG   CZ  NH1  sing N N 250 
ARG   CZ  NH2  doub N N 251 
ARG   NH1 HH11 sing N N 252 
ARG   NH1 HH12 sing N N 253 
ARG   NH2 HH21 sing N N 254 
ARG   NH2 HH22 sing N N 255 
ARG   OXT HXT  sing N N 256 
ASN   N   CA   sing N N 257 
ASN   N   H    sing N N 258 
ASN   N   H2   sing N N 259 
ASN   CA  C    sing N N 260 
ASN   CA  CB   sing N N 261 
ASN   CA  HA   sing N N 262 
ASN   C   O    doub N N 263 
ASN   C   OXT  sing N N 264 
ASN   CB  CG   sing N N 265 
ASN   CB  HB2  sing N N 266 
ASN   CB  HB3  sing N N 267 
ASN   CG  OD1  doub N N 268 
ASN   CG  ND2  sing N N 269 
ASN   ND2 HD21 sing N N 270 
ASN   ND2 HD22 sing N N 271 
ASN   OXT HXT  sing N N 272 
ASP   N   CA   sing N N 273 
ASP   N   H    sing N N 274 
ASP   N   H2   sing N N 275 
ASP   CA  C    sing N N 276 
ASP   CA  CB   sing N N 277 
ASP   CA  HA   sing N N 278 
ASP   C   O    doub N N 279 
ASP   C   OXT  sing N N 280 
ASP   CB  CG   sing N N 281 
ASP   CB  HB2  sing N N 282 
ASP   CB  HB3  sing N N 283 
ASP   CG  OD1  doub N N 284 
ASP   CG  OD2  sing N N 285 
ASP   OD2 HD2  sing N N 286 
ASP   OXT HXT  sing N N 287 
CYS   N   CA   sing N N 288 
CYS   N   H    sing N N 289 
CYS   N   H2   sing N N 290 
CYS   CA  C    sing N N 291 
CYS   CA  CB   sing N N 292 
CYS   CA  HA   sing N N 293 
CYS   C   O    doub N N 294 
CYS   C   OXT  sing N N 295 
CYS   CB  SG   sing N N 296 
CYS   CB  HB2  sing N N 297 
CYS   CB  HB3  sing N N 298 
CYS   SG  HG   sing N N 299 
CYS   OXT HXT  sing N N 300 
GLN   N   CA   sing N N 301 
GLN   N   H    sing N N 302 
GLN   N   H2   sing N N 303 
GLN   CA  C    sing N N 304 
GLN   CA  CB   sing N N 305 
GLN   CA  HA   sing N N 306 
GLN   C   O    doub N N 307 
GLN   C   OXT  sing N N 308 
GLN   CB  CG   sing N N 309 
GLN   CB  HB2  sing N N 310 
GLN   CB  HB3  sing N N 311 
GLN   CG  CD   sing N N 312 
GLN   CG  HG2  sing N N 313 
GLN   CG  HG3  sing N N 314 
GLN   CD  OE1  doub N N 315 
GLN   CD  NE2  sing N N 316 
GLN   NE2 HE21 sing N N 317 
GLN   NE2 HE22 sing N N 318 
GLN   OXT HXT  sing N N 319 
GLU   N   CA   sing N N 320 
GLU   N   H    sing N N 321 
GLU   N   H2   sing N N 322 
GLU   CA  C    sing N N 323 
GLU   CA  CB   sing N N 324 
GLU   CA  HA   sing N N 325 
GLU   C   O    doub N N 326 
GLU   C   OXT  sing N N 327 
GLU   CB  CG   sing N N 328 
GLU   CB  HB2  sing N N 329 
GLU   CB  HB3  sing N N 330 
GLU   CG  CD   sing N N 331 
GLU   CG  HG2  sing N N 332 
GLU   CG  HG3  sing N N 333 
GLU   CD  OE1  doub N N 334 
GLU   CD  OE2  sing N N 335 
GLU   OE2 HE2  sing N N 336 
GLU   OXT HXT  sing N N 337 
GLY   N   CA   sing N N 338 
GLY   N   H    sing N N 339 
GLY   N   H2   sing N N 340 
GLY   CA  C    sing N N 341 
GLY   CA  HA2  sing N N 342 
GLY   CA  HA3  sing N N 343 
GLY   C   O    doub N N 344 
GLY   C   OXT  sing N N 345 
GLY   OXT HXT  sing N N 346 
HIS   N   CA   sing N N 347 
HIS   N   H    sing N N 348 
HIS   N   H2   sing N N 349 
HIS   CA  C    sing N N 350 
HIS   CA  CB   sing N N 351 
HIS   CA  HA   sing N N 352 
HIS   C   O    doub N N 353 
HIS   C   OXT  sing N N 354 
HIS   CB  CG   sing N N 355 
HIS   CB  HB2  sing N N 356 
HIS   CB  HB3  sing N N 357 
HIS   CG  ND1  sing Y N 358 
HIS   CG  CD2  doub Y N 359 
HIS   ND1 CE1  doub Y N 360 
HIS   ND1 HD1  sing N N 361 
HIS   CD2 NE2  sing Y N 362 
HIS   CD2 HD2  sing N N 363 
HIS   CE1 NE2  sing Y N 364 
HIS   CE1 HE1  sing N N 365 
HIS   NE2 HE2  sing N N 366 
HIS   OXT HXT  sing N N 367 
ILE   N   CA   sing N N 368 
ILE   N   H    sing N N 369 
ILE   N   H2   sing N N 370 
ILE   CA  C    sing N N 371 
ILE   CA  CB   sing N N 372 
ILE   CA  HA   sing N N 373 
ILE   C   O    doub N N 374 
ILE   C   OXT  sing N N 375 
ILE   CB  CG1  sing N N 376 
ILE   CB  CG2  sing N N 377 
ILE   CB  HB   sing N N 378 
ILE   CG1 CD1  sing N N 379 
ILE   CG1 HG12 sing N N 380 
ILE   CG1 HG13 sing N N 381 
ILE   CG2 HG21 sing N N 382 
ILE   CG2 HG22 sing N N 383 
ILE   CG2 HG23 sing N N 384 
ILE   CD1 HD11 sing N N 385 
ILE   CD1 HD12 sing N N 386 
ILE   CD1 HD13 sing N N 387 
ILE   OXT HXT  sing N N 388 
LEU   N   CA   sing N N 389 
LEU   N   H    sing N N 390 
LEU   N   H2   sing N N 391 
LEU   CA  C    sing N N 392 
LEU   CA  CB   sing N N 393 
LEU   CA  HA   sing N N 394 
LEU   C   O    doub N N 395 
LEU   C   OXT  sing N N 396 
LEU   CB  CG   sing N N 397 
LEU   CB  HB2  sing N N 398 
LEU   CB  HB3  sing N N 399 
LEU   CG  CD1  sing N N 400 
LEU   CG  CD2  sing N N 401 
LEU   CG  HG   sing N N 402 
LEU   CD1 HD11 sing N N 403 
LEU   CD1 HD12 sing N N 404 
LEU   CD1 HD13 sing N N 405 
LEU   CD2 HD21 sing N N 406 
LEU   CD2 HD22 sing N N 407 
LEU   CD2 HD23 sing N N 408 
LEU   OXT HXT  sing N N 409 
LYS   N   CA   sing N N 410 
LYS   N   H    sing N N 411 
LYS   N   H2   sing N N 412 
LYS   CA  C    sing N N 413 
LYS   CA  CB   sing N N 414 
LYS   CA  HA   sing N N 415 
LYS   C   O    doub N N 416 
LYS   C   OXT  sing N N 417 
LYS   CB  CG   sing N N 418 
LYS   CB  HB2  sing N N 419 
LYS   CB  HB3  sing N N 420 
LYS   CG  CD   sing N N 421 
LYS   CG  HG2  sing N N 422 
LYS   CG  HG3  sing N N 423 
LYS   CD  CE   sing N N 424 
LYS   CD  HD2  sing N N 425 
LYS   CD  HD3  sing N N 426 
LYS   CE  NZ   sing N N 427 
LYS   CE  HE2  sing N N 428 
LYS   CE  HE3  sing N N 429 
LYS   NZ  HZ1  sing N N 430 
LYS   NZ  HZ2  sing N N 431 
LYS   NZ  HZ3  sing N N 432 
LYS   OXT HXT  sing N N 433 
MET   N   CA   sing N N 434 
MET   N   H    sing N N 435 
MET   N   H2   sing N N 436 
MET   CA  C    sing N N 437 
MET   CA  CB   sing N N 438 
MET   CA  HA   sing N N 439 
MET   C   O    doub N N 440 
MET   C   OXT  sing N N 441 
MET   CB  CG   sing N N 442 
MET   CB  HB2  sing N N 443 
MET   CB  HB3  sing N N 444 
MET   CG  SD   sing N N 445 
MET   CG  HG2  sing N N 446 
MET   CG  HG3  sing N N 447 
MET   SD  CE   sing N N 448 
MET   CE  HE1  sing N N 449 
MET   CE  HE2  sing N N 450 
MET   CE  HE3  sing N N 451 
MET   OXT HXT  sing N N 452 
NAG   C1  C2   sing N N 453 
NAG   C1  O1   sing N N 454 
NAG   C1  O5   sing N N 455 
NAG   C1  H1   sing N N 456 
NAG   C2  C3   sing N N 457 
NAG   C2  N2   sing N N 458 
NAG   C2  H2   sing N N 459 
NAG   C3  C4   sing N N 460 
NAG   C3  O3   sing N N 461 
NAG   C3  H3   sing N N 462 
NAG   C4  C5   sing N N 463 
NAG   C4  O4   sing N N 464 
NAG   C4  H4   sing N N 465 
NAG   C5  C6   sing N N 466 
NAG   C5  O5   sing N N 467 
NAG   C5  H5   sing N N 468 
NAG   C6  O6   sing N N 469 
NAG   C6  H61  sing N N 470 
NAG   C6  H62  sing N N 471 
NAG   C7  C8   sing N N 472 
NAG   C7  N2   sing N N 473 
NAG   C7  O7   doub N N 474 
NAG   C8  H81  sing N N 475 
NAG   C8  H82  sing N N 476 
NAG   C8  H83  sing N N 477 
NAG   N2  HN2  sing N N 478 
NAG   O1  HO1  sing N N 479 
NAG   O3  HO3  sing N N 480 
NAG   O4  HO4  sing N N 481 
NAG   O6  HO6  sing N N 482 
PHE   N   CA   sing N N 483 
PHE   N   H    sing N N 484 
PHE   N   H2   sing N N 485 
PHE   CA  C    sing N N 486 
PHE   CA  CB   sing N N 487 
PHE   CA  HA   sing N N 488 
PHE   C   O    doub N N 489 
PHE   C   OXT  sing N N 490 
PHE   CB  CG   sing N N 491 
PHE   CB  HB2  sing N N 492 
PHE   CB  HB3  sing N N 493 
PHE   CG  CD1  doub Y N 494 
PHE   CG  CD2  sing Y N 495 
PHE   CD1 CE1  sing Y N 496 
PHE   CD1 HD1  sing N N 497 
PHE   CD2 CE2  doub Y N 498 
PHE   CD2 HD2  sing N N 499 
PHE   CE1 CZ   doub Y N 500 
PHE   CE1 HE1  sing N N 501 
PHE   CE2 CZ   sing Y N 502 
PHE   CE2 HE2  sing N N 503 
PHE   CZ  HZ   sing N N 504 
PHE   OXT HXT  sing N N 505 
PRO   N   CA   sing N N 506 
PRO   N   CD   sing N N 507 
PRO   N   H    sing N N 508 
PRO   CA  C    sing N N 509 
PRO   CA  CB   sing N N 510 
PRO   CA  HA   sing N N 511 
PRO   C   O    doub N N 512 
PRO   C   OXT  sing N N 513 
PRO   CB  CG   sing N N 514 
PRO   CB  HB2  sing N N 515 
PRO   CB  HB3  sing N N 516 
PRO   CG  CD   sing N N 517 
PRO   CG  HG2  sing N N 518 
PRO   CG  HG3  sing N N 519 
PRO   CD  HD2  sing N N 520 
PRO   CD  HD3  sing N N 521 
PRO   OXT HXT  sing N N 522 
SER   N   CA   sing N N 523 
SER   N   H    sing N N 524 
SER   N   H2   sing N N 525 
SER   CA  C    sing N N 526 
SER   CA  CB   sing N N 527 
SER   CA  HA   sing N N 528 
SER   C   O    doub N N 529 
SER   C   OXT  sing N N 530 
SER   CB  OG   sing N N 531 
SER   CB  HB2  sing N N 532 
SER   CB  HB3  sing N N 533 
SER   OG  HG   sing N N 534 
SER   OXT HXT  sing N N 535 
THR   N   CA   sing N N 536 
THR   N   H    sing N N 537 
THR   N   H2   sing N N 538 
THR   CA  C    sing N N 539 
THR   CA  CB   sing N N 540 
THR   CA  HA   sing N N 541 
THR   C   O    doub N N 542 
THR   C   OXT  sing N N 543 
THR   CB  OG1  sing N N 544 
THR   CB  CG2  sing N N 545 
THR   CB  HB   sing N N 546 
THR   OG1 HG1  sing N N 547 
THR   CG2 HG21 sing N N 548 
THR   CG2 HG22 sing N N 549 
THR   CG2 HG23 sing N N 550 
THR   OXT HXT  sing N N 551 
TRP   N   CA   sing N N 552 
TRP   N   H    sing N N 553 
TRP   N   H2   sing N N 554 
TRP   CA  C    sing N N 555 
TRP   CA  CB   sing N N 556 
TRP   CA  HA   sing N N 557 
TRP   C   O    doub N N 558 
TRP   C   OXT  sing N N 559 
TRP   CB  CG   sing N N 560 
TRP   CB  HB2  sing N N 561 
TRP   CB  HB3  sing N N 562 
TRP   CG  CD1  doub Y N 563 
TRP   CG  CD2  sing Y N 564 
TRP   CD1 NE1  sing Y N 565 
TRP   CD1 HD1  sing N N 566 
TRP   CD2 CE2  doub Y N 567 
TRP   CD2 CE3  sing Y N 568 
TRP   NE1 CE2  sing Y N 569 
TRP   NE1 HE1  sing N N 570 
TRP   CE2 CZ2  sing Y N 571 
TRP   CE3 CZ3  doub Y N 572 
TRP   CE3 HE3  sing N N 573 
TRP   CZ2 CH2  doub Y N 574 
TRP   CZ2 HZ2  sing N N 575 
TRP   CZ3 CH2  sing Y N 576 
TRP   CZ3 HZ3  sing N N 577 
TRP   CH2 HH2  sing N N 578 
TRP   OXT HXT  sing N N 579 
TYR   N   CA   sing N N 580 
TYR   N   H    sing N N 581 
TYR   N   H2   sing N N 582 
TYR   CA  C    sing N N 583 
TYR   CA  CB   sing N N 584 
TYR   CA  HA   sing N N 585 
TYR   C   O    doub N N 586 
TYR   C   OXT  sing N N 587 
TYR   CB  CG   sing N N 588 
TYR   CB  HB2  sing N N 589 
TYR   CB  HB3  sing N N 590 
TYR   CG  CD1  doub Y N 591 
TYR   CG  CD2  sing Y N 592 
TYR   CD1 CE1  sing Y N 593 
TYR   CD1 HD1  sing N N 594 
TYR   CD2 CE2  doub Y N 595 
TYR   CD2 HD2  sing N N 596 
TYR   CE1 CZ   doub Y N 597 
TYR   CE1 HE1  sing N N 598 
TYR   CE2 CZ   sing Y N 599 
TYR   CE2 HE2  sing N N 600 
TYR   CZ  OH   sing N N 601 
TYR   OH  HH   sing N N 602 
TYR   OXT HXT  sing N N 603 
VAL   N   CA   sing N N 604 
VAL   N   H    sing N N 605 
VAL   N   H2   sing N N 606 
VAL   CA  C    sing N N 607 
VAL   CA  CB   sing N N 608 
VAL   CA  HA   sing N N 609 
VAL   C   O    doub N N 610 
VAL   C   OXT  sing N N 611 
VAL   CB  CG1  sing N N 612 
VAL   CB  CG2  sing N N 613 
VAL   CB  HB   sing N N 614 
VAL   CG1 HG11 sing N N 615 
VAL   CG1 HG12 sing N N 616 
VAL   CG1 HG13 sing N N 617 
VAL   CG2 HG21 sing N N 618 
VAL   CG2 HG22 sing N N 619 
VAL   CG2 HG23 sing N N 620 
VAL   OXT HXT  sing N N 621 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-20 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9BVM 
_em_admin.last_update        2025-03-26 
_em_admin.map_release_date   2025-01-22 
_em_admin.title              
'Vitamin K-dependent gamma-carboxylase with protein C propeptide and glutamate-rich region and with vitamin K hydroquinone' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 150   mM NaCl       1 'Sodium chloride'        
1 20    mM C8H18N2O4S 2 HEPES                    
1 0.005 %  C56H92O25  3 Glyco-diosgenin          
1 0.055 mM C31H48O2   4 'Vitamin K hydroquinone' 
1 1.84  mM NaHCO3     5 'Sodium bicarbonate'     
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.11 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 HEK293S 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              'pEG BacMam' 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         54.8 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    1 
_em_image_recording.num_real_images                     5313 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   1322129 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.21.1_5286: 
'IMAGE ACQUISITION'             ? 2  1 ? 1 ?      ?            
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?            
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?            
CLASSIFICATION                  ? 5  1 1 1 ?      ?            
MASKING                         ? 6  1 1 1 ?      ?            
RECONSTRUCTION                  ? 7  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?            
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?            
'CTF CORRECTION'                ? 10 1 1 1 ?      ?            
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?            
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?            
'MODEL FITTING'                 ? 13 1 1 1 ?      ?            
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?            
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?            
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?            
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?            
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?            
OTHER                           ? 19 1 1 1 ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)'             'United States' HL121718 1 
'American Heart Association'                                                                      'United States' 
'Established Investigator Award' 2 
'American Heart Association'                                                                      'United States' 
'Collaborative Sciences Award'   3 
'W. M. Keck Foundation'                                                                           'United States' 
'Forefront of Science Award'     4 
'Childrens Discovery Institute of Washington University and St. Louis Childrens Hospital'         'United States' 'MCII 2020-854' 
5 
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 'United States' AI158500 6 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)'        'United States' GM131008 7 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
3 NAG 1 n 
3 NAG 2 n 
# 
_atom_sites.entry_id                    9BVM 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ASP   A 1 5   ? 109.559 136.282 131.229 1.00 78.78  ? 31  ASP   A N   1 
ATOM   2    C CA  . ASP   A 1 5   ? 108.899 136.083 129.946 1.00 80.42  ? 31  ASP   A CA  1 
ATOM   3    C C   . ASP   A 1 5   ? 109.550 136.936 128.868 1.00 75.82  ? 31  ASP   A C   1 
ATOM   4    O O   . ASP   A 1 5   ? 109.829 136.458 127.770 1.00 75.02  ? 31  ASP   A O   1 
ATOM   5    C CB  . ASP   A 1 5   ? 107.410 136.418 130.052 1.00 86.56  ? 31  ASP   A CB  1 
ATOM   6    C CG  . ASP   A 1 5   ? 106.690 135.554 131.068 1.00 92.14  ? 31  ASP   A CG  1 
ATOM   7    O OD1 . ASP   A 1 5   ? 107.120 134.400 131.281 1.00 94.44  ? 31  ASP   A OD1 1 
ATOM   8    O OD2 . ASP   A 1 5   ? 105.693 136.027 131.652 1.00 91.77  ? 31  ASP   A OD2 1 
ATOM   9    N N   . SER   A 1 6   ? 109.783 138.205 129.185 1.00 77.04  ? 32  SER   A N   1 
ATOM   10   C CA  . SER   A 1 6   ? 110.431 139.102 128.241 1.00 78.79  ? 32  SER   A CA  1 
ATOM   11   C C   . SER   A 1 6   ? 111.851 138.630 127.958 1.00 76.36  ? 32  SER   A C   1 
ATOM   12   O O   . SER   A 1 6   ? 112.502 138.008 128.801 1.00 77.02  ? 32  SER   A O   1 
ATOM   13   C CB  . SER   A 1 6   ? 110.457 140.530 128.790 1.00 79.60  ? 32  SER   A CB  1 
ATOM   14   O OG  . SER   A 1 6   ? 109.159 140.966 129.155 1.00 78.85  ? 32  SER   A OG  1 
ATOM   15   N N   . ARG   A 1 7   ? 112.325 138.918 126.744 1.00 74.29  ? 33  ARG   A N   1 
ATOM   16   C CA  . ARG   A 1 7   ? 113.705 138.592 126.404 1.00 79.21  ? 33  ARG   A CA  1 
ATOM   17   C C   . ARG   A 1 7   ? 114.674 139.327 127.319 1.00 71.38  ? 33  ARG   A C   1 
ATOM   18   O O   . ARG   A 1 7   ? 115.665 138.748 127.785 1.00 69.85  ? 33  ARG   A O   1 
ATOM   19   C CB  . ARG   A 1 7   ? 113.978 138.932 124.939 1.00 85.66  ? 33  ARG   A CB  1 
ATOM   20   C CG  . ARG   A 1 7   ? 113.144 138.125 123.956 1.00 92.07  ? 33  ARG   A CG  1 
ATOM   21   C CD  . ARG   A 1 7   ? 113.487 138.465 122.515 1.00 98.14  ? 33  ARG   A CD  1 
ATOM   22   N NE  . ARG   A 1 7   ? 112.715 137.667 121.569 1.00 105.72 ? 33  ARG   A NE  1 
ATOM   23   C CZ  . ARG   A 1 7   ? 112.820 137.742 120.247 1.00 111.00 ? 33  ARG   A CZ  1 
ATOM   24   N NH1 . ARG   A 1 7   ? 113.665 138.577 119.661 1.00 110.11 ? 33  ARG   A NH1 1 
ATOM   25   N NH2 . ARG   A 1 7   ? 112.057 136.956 119.492 1.00 113.68 ? 33  ARG   A NH2 1 
ATOM   26   N N   . ILE   A 1 8   ? 114.400 140.604 127.593 1.00 67.52  ? 34  ILE   A N   1 
ATOM   27   C CA  . ILE   A 1 8   ? 115.207 141.346 128.556 1.00 67.32  ? 34  ILE   A CA  1 
ATOM   28   C C   . ILE   A 1 8   ? 115.108 140.692 129.927 1.00 61.96  ? 34  ILE   A C   1 
ATOM   29   O O   . ILE   A 1 8   ? 116.074 140.689 130.699 1.00 61.55  ? 34  ILE   A O   1 
ATOM   30   C CB  . ILE   A 1 8   ? 114.780 142.829 128.593 1.00 73.45  ? 34  ILE   A CB  1 
ATOM   31   C CG1 . ILE   A 1 8   ? 115.336 143.592 127.378 1.00 73.66  ? 34  ILE   A CG1 1 
ATOM   32   C CG2 . ILE   A 1 8   ? 115.241 143.512 129.894 1.00 70.54  ? 34  ILE   A CG2 1 
ATOM   33   C CD1 . ILE   A 1 8   ? 114.704 143.231 126.047 1.00 72.66  ? 34  ILE   A CD1 1 
ATOM   34   N N   . GLY   A 1 9   ? 113.942 140.137 130.252 1.00 61.55  ? 35  GLY   A N   1 
ATOM   35   C CA  . GLY   A 1 9   ? 113.778 139.491 131.542 1.00 61.17  ? 35  GLY   A CA  1 
ATOM   36   C C   . GLY   A 1 9   ? 114.719 138.320 131.733 1.00 56.17  ? 35  GLY   A C   1 
ATOM   37   O O   . GLY   A 1 9   ? 115.315 138.160 132.800 1.00 59.96  ? 35  GLY   A O   1 
ATOM   38   N N   . LYS   A 1 10  ? 114.870 137.488 130.707 1.00 54.86  ? 36  LYS   A N   1 
ATOM   39   C CA  . LYS   A 1 10  ? 115.782 136.358 130.813 1.00 58.43  ? 36  LYS   A CA  1 
ATOM   40   C C   . LYS   A 1 10  ? 117.237 136.799 130.707 1.00 60.24  ? 36  LYS   A C   1 
ATOM   41   O O   . LYS   A 1 10  ? 118.095 136.278 131.427 1.00 61.60  ? 36  LYS   A O   1 
ATOM   42   C CB  . LYS   A 1 10  ? 115.462 135.317 129.742 1.00 65.09  ? 36  LYS   A CB  1 
ATOM   43   C CG  . LYS   A 1 10  ? 116.110 133.962 129.998 1.00 66.13  ? 36  LYS   A CG  1 
ATOM   44   C CD  . LYS   A 1 10  ? 115.771 132.936 128.918 1.00 73.44  ? 36  LYS   A CD  1 
ATOM   45   C CE  . LYS   A 1 10  ? 114.305 132.501 128.940 1.00 76.27  ? 36  LYS   A CE  1 
ATOM   46   N NZ  . LYS   A 1 10  ? 113.882 131.929 130.250 1.00 73.00  ? 36  LYS   A NZ  1 
ATOM   47   N N   . LEU   A 1 11  ? 117.537 137.745 129.812 1.00 60.31  ? 37  LEU   A N   1 
ATOM   48   C CA  . LEU   A 1 11  ? 118.923 138.173 129.635 1.00 56.76  ? 37  LEU   A CA  1 
ATOM   49   C C   . LEU   A 1 11  ? 119.462 138.835 130.895 1.00 53.00  ? 37  LEU   A C   1 
ATOM   50   O O   . LEU   A 1 11  ? 120.517 138.448 131.409 1.00 54.70  ? 37  LEU   A O   1 
ATOM   51   C CB  . LEU   A 1 11  ? 119.033 139.136 128.452 1.00 57.75  ? 37  LEU   A CB  1 
ATOM   52   C CG  . LEU   A 1 11  ? 118.826 138.592 127.041 1.00 59.74  ? 37  LEU   A CG  1 
ATOM   53   C CD1 . LEU   A 1 11  ? 118.834 139.737 126.048 1.00 56.81  ? 37  LEU   A CD1 1 
ATOM   54   C CD2 . LEU   A 1 11  ? 119.893 137.568 126.685 1.00 59.77  ? 37  LEU   A CD2 1 
ATOM   55   N N   . LEU   A 1 12  ? 118.746 139.835 131.411 1.00 48.63  ? 38  LEU   A N   1 
ATOM   56   C CA  . LEU   A 1 12  ? 119.219 140.625 132.539 1.00 48.37  ? 38  LEU   A CA  1 
ATOM   57   C C   . LEU   A 1 12  ? 118.696 140.140 133.885 1.00 51.02  ? 38  LEU   A C   1 
ATOM   58   O O   . LEU   A 1 12  ? 119.311 140.445 134.911 1.00 52.93  ? 38  LEU   A O   1 
ATOM   59   C CB  . LEU   A 1 12  ? 118.825 142.095 132.356 1.00 49.81  ? 38  LEU   A CB  1 
ATOM   60   C CG  . LEU   A 1 12  ? 119.510 142.852 131.214 1.00 49.97  ? 38  LEU   A CG  1 
ATOM   61   C CD1 . LEU   A 1 12  ? 118.886 142.565 129.848 1.00 57.22  ? 38  LEU   A CD1 1 
ATOM   62   C CD2 . LEU   A 1 12  ? 119.495 144.344 131.504 1.00 51.88  ? 38  LEU   A CD2 1 
ATOM   63   N N   . GLY   A 1 13  ? 117.588 139.401 133.908 1.00 52.37  ? 39  GLY   A N   1 
ATOM   64   C CA  . GLY   A 1 13  ? 117.027 138.884 135.135 1.00 48.12  ? 39  GLY   A CA  1 
ATOM   65   C C   . GLY   A 1 13  ? 116.028 139.784 135.829 1.00 45.00  ? 39  GLY   A C   1 
ATOM   66   O O   . GLY   A 1 13  ? 115.432 139.358 136.824 1.00 48.30  ? 39  GLY   A O   1 
ATOM   67   N N   . PHE   A 1 14  ? 115.819 141.007 135.345 1.00 46.13  ? 40  PHE   A N   1 
ATOM   68   C CA  . PHE   A 1 14  ? 114.873 141.932 135.952 1.00 50.01  ? 40  PHE   A CA  1 
ATOM   69   C C   . PHE   A 1 14  ? 114.176 142.733 134.865 1.00 53.01  ? 40  PHE   A C   1 
ATOM   70   O O   . PHE   A 1 14  ? 114.756 143.020 133.815 1.00 58.15  ? 40  PHE   A O   1 
ATOM   71   C CB  . PHE   A 1 14  ? 115.565 142.878 136.938 1.00 50.64  ? 40  PHE   A CB  1 
ATOM   72   C CG  . PHE   A 1 14  ? 116.370 143.959 136.282 1.00 50.45  ? 40  PHE   A CG  1 
ATOM   73   C CD1 . PHE   A 1 14  ? 117.545 143.664 135.622 1.00 49.02  ? 40  PHE   A CD1 1 
ATOM   74   C CD2 . PHE   A 1 14  ? 115.958 145.275 136.341 1.00 55.19  ? 40  PHE   A CD2 1 
ATOM   75   C CE1 . PHE   A 1 14  ? 118.287 144.655 135.027 1.00 52.77  ? 40  PHE   A CE1 1 
ATOM   76   C CE2 . PHE   A 1 14  ? 116.695 146.270 135.746 1.00 56.46  ? 40  PHE   A CE2 1 
ATOM   77   C CZ  . PHE   A 1 14  ? 117.862 145.960 135.088 1.00 56.36  ? 40  PHE   A CZ  1 
ATOM   78   N N   . GLU   A 1 15  ? 112.930 143.102 135.136 1.00 53.88  ? 41  GLU   A N   1 
ATOM   79   C CA  . GLU   A 1 15  ? 112.098 143.821 134.185 1.00 59.77  ? 41  GLU   A CA  1 
ATOM   80   C C   . GLU   A 1 15  ? 112.177 145.326 134.425 1.00 65.46  ? 41  GLU   A C   1 
ATOM   81   O O   . GLU   A 1 15  ? 112.552 145.792 135.503 1.00 69.85  ? 41  GLU   A O   1 
ATOM   82   C CB  . GLU   A 1 15  ? 110.648 143.351 134.283 1.00 61.11  ? 41  GLU   A CB  1 
ATOM   83   C CG  . GLU   A 1 15  ? 110.421 141.925 133.809 1.00 66.46  ? 41  GLU   A CG  1 
ATOM   84   C CD  . GLU   A 1 15  ? 110.366 141.806 132.299 1.00 73.70  ? 41  GLU   A CD  1 
ATOM   85   O OE1 . GLU   A 1 15  ? 110.797 142.751 131.605 1.00 73.94  ? 41  GLU   A OE1 1 
ATOM   86   O OE2 . GLU   A 1 15  ? 109.882 140.768 131.802 1.00 75.00  ? 41  GLU   A OE2 1 
ATOM   87   N N   . TRP   A 1 16  ? 111.819 146.087 133.388 1.00 60.68  ? 42  TRP   A N   1 
ATOM   88   C CA  . TRP   A 1 16  ? 111.957 147.538 133.449 1.00 60.97  ? 42  TRP   A CA  1 
ATOM   89   C C   . TRP   A 1 16  ? 111.003 148.149 134.465 1.00 62.57  ? 42  TRP   A C   1 
ATOM   90   O O   . TRP   A 1 16  ? 111.371 149.090 135.180 1.00 67.99  ? 42  TRP   A O   1 
ATOM   91   C CB  . TRP   A 1 16  ? 111.727 148.142 132.068 1.00 67.67  ? 42  TRP   A CB  1 
ATOM   92   C CG  . TRP   A 1 16  ? 112.674 147.629 131.039 1.00 75.06  ? 42  TRP   A CG  1 
ATOM   93   C CD1 . TRP   A 1 16  ? 112.410 146.707 130.070 1.00 75.32  ? 42  TRP   A CD1 1 
ATOM   94   C CD2 . TRP   A 1 16  ? 114.047 148.000 130.876 1.00 77.95  ? 42  TRP   A CD2 1 
ATOM   95   N NE1 . TRP   A 1 16  ? 113.532 146.483 129.311 1.00 76.96  ? 42  TRP   A NE1 1 
ATOM   96   C CE2 . TRP   A 1 16  ? 114.551 147.264 129.786 1.00 79.86  ? 42  TRP   A CE2 1 
ATOM   97   C CE3 . TRP   A 1 16  ? 114.899 148.884 131.545 1.00 79.16  ? 42  TRP   A CE3 1 
ATOM   98   C CZ2 . TRP   A 1 16  ? 115.868 147.386 129.349 1.00 85.32  ? 42  TRP   A CZ2 1 
ATOM   99   C CZ3 . TRP   A 1 16  ? 116.206 149.003 131.110 1.00 85.40  ? 42  TRP   A CZ3 1 
ATOM   100  C CH2 . TRP   A 1 16  ? 116.678 148.258 130.022 1.00 88.23  ? 42  TRP   A CH2 1 
ATOM   101  N N   . THR   A 1 17  ? 109.776 147.629 134.550 1.00 57.35  ? 43  THR   A N   1 
ATOM   102  C CA  . THR   A 1 17  ? 108.794 148.181 135.479 1.00 60.39  ? 43  THR   A CA  1 
ATOM   103  C C   . THR   A 1 17  ? 109.246 148.083 136.930 1.00 58.47  ? 43  THR   A C   1 
ATOM   104  O O   . THR   A 1 17  ? 108.742 148.831 137.774 1.00 57.24  ? 43  THR   A O   1 
ATOM   105  C CB  . THR   A 1 17  ? 107.444 147.476 135.311 1.00 68.24  ? 43  THR   A CB  1 
ATOM   106  O OG1 . THR   A 1 17  ? 106.473 148.094 136.165 1.00 70.65  ? 43  THR   A OG1 1 
ATOM   107  C CG2 . THR   A 1 17  ? 107.535 145.983 135.651 1.00 66.35  ? 43  THR   A CG2 1 
ATOM   108  N N   . ASP   A 1 18  ? 110.184 147.186 137.239 1.00 60.65  ? 44  ASP   A N   1 
ATOM   109  C CA  . ASP   A 1 18  ? 110.721 147.100 138.590 1.00 61.31  ? 44  ASP   A CA  1 
ATOM   110  C C   . ASP   A 1 18  ? 111.453 148.369 139.007 1.00 61.22  ? 44  ASP   A C   1 
ATOM   111  O O   . ASP   A 1 18  ? 111.610 148.609 140.209 1.00 63.51  ? 44  ASP   A O   1 
ATOM   112  C CB  . ASP   A 1 18  ? 111.664 145.902 138.700 1.00 60.26  ? 44  ASP   A CB  1 
ATOM   113  C CG  . ASP   A 1 18  ? 110.985 144.593 138.356 1.00 66.30  ? 44  ASP   A CG  1 
ATOM   114  O OD1 . ASP   A 1 18  ? 109.766 144.471 138.599 1.00 70.22  ? 44  ASP   A OD1 1 
ATOM   115  O OD2 . ASP   A 1 18  ? 111.670 143.684 137.841 1.00 65.85  ? 44  ASP   A OD2 1 
ATOM   116  N N   . LEU   A 1 19  ? 111.900 149.185 138.051 1.00 57.19  ? 45  LEU   A N   1 
ATOM   117  C CA  . LEU   A 1 19  ? 112.624 150.414 138.341 1.00 54.52  ? 45  LEU   A CA  1 
ATOM   118  C C   . LEU   A 1 19  ? 111.724 151.643 138.353 1.00 55.88  ? 45  LEU   A C   1 
ATOM   119  O O   . LEU   A 1 19  ? 112.232 152.765 138.421 1.00 60.68  ? 45  LEU   A O   1 
ATOM   120  C CB  . LEU   A 1 19  ? 113.746 150.615 137.323 1.00 58.67  ? 45  LEU   A CB  1 
ATOM   121  C CG  . LEU   A 1 19  ? 114.774 149.492 137.167 1.00 63.99  ? 45  LEU   A CG  1 
ATOM   122  C CD1 . LEU   A 1 19  ? 115.766 149.850 136.067 1.00 63.29  ? 45  LEU   A CD1 1 
ATOM   123  C CD2 . LEU   A 1 19  ? 115.497 149.209 138.476 1.00 63.12  ? 45  LEU   A CD2 1 
ATOM   124  N N   . SER   A 1 20  ? 110.402 151.464 138.286 1.00 54.48  ? 46  SER   A N   1 
ATOM   125  C CA  . SER   A 1 20  ? 109.507 152.616 138.259 1.00 49.77  ? 46  SER   A CA  1 
ATOM   126  C C   . SER   A 1 20  ? 109.519 153.368 139.582 1.00 48.19  ? 46  SER   A C   1 
ATOM   127  O O   . SER   A 1 20  ? 109.510 154.604 139.594 1.00 49.77  ? 46  SER   A O   1 
ATOM   128  C CB  . SER   A 1 20  ? 108.087 152.172 137.917 1.00 55.73  ? 46  SER   A CB  1 
ATOM   129  O OG  . SER   A 1 20  ? 107.475 151.525 139.017 1.00 62.95  ? 46  SER   A OG  1 
ATOM   130  N N   . SER   A 1 21  ? 109.539 152.646 140.702 1.00 50.54  ? 47  SER   A N   1 
ATOM   131  C CA  . SER   A 1 21  ? 109.368 153.230 142.026 1.00 51.12  ? 47  SER   A CA  1 
ATOM   132  C C   . SER   A 1 21  ? 110.429 152.708 142.982 1.00 48.36  ? 47  SER   A C   1 
ATOM   133  O O   . SER   A 1 21  ? 111.088 151.697 142.730 1.00 51.83  ? 47  SER   A O   1 
ATOM   134  C CB  . SER   A 1 21  ? 107.977 152.928 142.596 1.00 51.23  ? 47  SER   A CB  1 
ATOM   135  O OG  . SER   A 1 21  ? 107.843 153.454 143.905 1.00 47.68  ? 47  SER   A OG  1 
ATOM   136  N N   . TRP   A 1 22  ? 110.585 153.429 144.093 1.00 43.66  ? 48  TRP   A N   1 
ATOM   137  C CA  . TRP   A 1 22  ? 111.545 153.031 145.115 1.00 45.63  ? 48  TRP   A CA  1 
ATOM   138  C C   . TRP   A 1 22  ? 111.145 151.710 145.758 1.00 53.22  ? 48  TRP   A C   1 
ATOM   139  O O   . TRP   A 1 22  ? 112.003 150.873 146.062 1.00 54.41  ? 48  TRP   A O   1 
ATOM   140  C CB  . TRP   A 1 22  ? 111.664 154.134 146.165 1.00 42.98  ? 48  TRP   A CB  1 
ATOM   141  C CG  . TRP   A 1 22  ? 112.721 153.896 147.194 1.00 43.38  ? 48  TRP   A CG  1 
ATOM   142  C CD1 . TRP   A 1 22  ? 112.548 153.849 148.540 1.00 45.55  ? 48  TRP   A CD1 1 
ATOM   143  C CD2 . TRP   A 1 22  ? 114.118 153.675 146.961 1.00 48.14  ? 48  TRP   A CD2 1 
ATOM   144  N NE1 . TRP   A 1 22  ? 113.746 153.614 149.165 1.00 48.36  ? 48  TRP   A NE1 1 
ATOM   145  C CE2 . TRP   A 1 22  ? 114.727 153.502 148.216 1.00 46.24  ? 48  TRP   A CE2 1 
ATOM   146  C CE3 . TRP   A 1 22  ? 114.914 153.607 145.813 1.00 53.70  ? 48  TRP   A CE3 1 
ATOM   147  C CZ2 . TRP   A 1 22  ? 116.089 153.263 148.358 1.00 45.36  ? 48  TRP   A CZ2 1 
ATOM   148  C CZ3 . TRP   A 1 22  ? 116.267 153.369 145.958 1.00 51.48  ? 48  TRP   A CZ3 1 
ATOM   149  C CH2 . TRP   A 1 22  ? 116.840 153.201 147.221 1.00 48.45  ? 48  TRP   A CH2 1 
ATOM   150  N N   . ARG   A 1 23  ? 109.843 151.507 145.977 1.00 55.79  ? 49  ARG   A N   1 
ATOM   151  C CA  . ARG   A 1 23  ? 109.370 150.268 146.586 1.00 47.99  ? 49  ARG   A CA  1 
ATOM   152  C C   . ARG   A 1 23  ? 109.695 149.063 145.713 1.00 46.10  ? 49  ARG   A C   1 
ATOM   153  O O   . ARG   A 1 23  ? 110.175 148.036 146.211 1.00 51.70  ? 49  ARG   A O   1 
ATOM   154  C CB  . ARG   A 1 23  ? 107.867 150.367 146.834 1.00 48.27  ? 49  ARG   A CB  1 
ATOM   155  C CG  . ARG   A 1 23  ? 107.239 149.166 147.513 1.00 48.55  ? 49  ARG   A CG  1 
ATOM   156  C CD  . ARG   A 1 23  ? 105.800 149.469 147.893 1.00 50.72  ? 49  ARG   A CD  1 
ATOM   157  N NE  . ARG   A 1 23  ? 105.186 148.389 148.656 1.00 55.72  ? 49  ARG   A NE  1 
ATOM   158  C CZ  . ARG   A 1 23  ? 104.044 148.488 149.324 1.00 58.34  ? 49  ARG   A CZ  1 
ATOM   159  N NH1 . ARG   A 1 23  ? 103.354 149.617 149.363 1.00 57.40  ? 49  ARG   A NH1 1 
ATOM   160  N NH2 . ARG   A 1 23  ? 103.583 147.425 149.977 1.00 58.91  ? 49  ARG   A NH2 1 
ATOM   161  N N   . ARG   A 1 24  ? 109.455 149.172 144.407 1.00 44.65  ? 50  ARG   A N   1 
ATOM   162  C CA  . ARG   A 1 24  ? 109.746 148.057 143.515 1.00 48.59  ? 50  ARG   A CA  1 
ATOM   163  C C   . ARG   A 1 24  ? 111.243 147.806 143.419 1.00 46.30  ? 50  ARG   A C   1 
ATOM   164  O O   . ARG   A 1 24  ? 111.681 146.652 143.343 1.00 51.90  ? 50  ARG   A O   1 
ATOM   165  C CB  . ARG   A 1 24  ? 109.149 148.321 142.134 1.00 56.55  ? 50  ARG   A CB  1 
ATOM   166  C CG  . ARG   A 1 24  ? 107.647 148.572 142.160 1.00 60.38  ? 50  ARG   A CG  1 
ATOM   167  C CD  . ARG   A 1 24  ? 107.074 148.713 140.764 1.00 61.47  ? 50  ARG   A CD  1 
ATOM   168  N NE  . ARG   A 1 24  ? 105.694 149.184 140.791 1.00 65.88  ? 50  ARG   A NE  1 
ATOM   169  C CZ  . ARG   A 1 24  ? 104.959 149.447 139.717 1.00 72.25  ? 50  ARG   A CZ  1 
ATOM   170  N NH1 . ARG   A 1 24  ? 105.437 149.298 138.491 1.00 68.20  ? 50  ARG   A NH1 1 
ATOM   171  N NH2 . ARG   A 1 24  ? 103.709 149.872 139.877 1.00 73.19  ? 50  ARG   A NH2 1 
ATOM   172  N N   . LEU   A 1 25  ? 112.045 148.871 143.424 1.00 42.86  ? 51  LEU   A N   1 
ATOM   173  C CA  . LEU   A 1 25  ? 113.494 148.702 143.409 1.00 45.13  ? 51  LEU   A CA  1 
ATOM   174  C C   . LEU   A 1 25  ? 113.978 147.987 144.662 1.00 46.22  ? 51  LEU   A C   1 
ATOM   175  O O   . LEU   A 1 25  ? 114.834 147.097 144.588 1.00 49.94  ? 51  LEU   A O   1 
ATOM   176  C CB  . LEU   A 1 25  ? 114.171 150.065 143.271 1.00 46.59  ? 51  LEU   A CB  1 
ATOM   177  C CG  . LEU   A 1 25  ? 115.699 150.108 143.226 1.00 47.22  ? 51  LEU   A CG  1 
ATOM   178  C CD1 . LEU   A 1 25  ? 116.230 149.258 142.094 1.00 49.88  ? 51  LEU   A CD1 1 
ATOM   179  C CD2 . LEU   A 1 25  ? 116.186 151.535 143.077 1.00 47.46  ? 51  LEU   A CD2 1 
ATOM   180  N N   . VAL   A 1 26  ? 113.444 148.364 145.824 1.00 43.21  ? 52  VAL   A N   1 
ATOM   181  C CA  . VAL   A 1 26  ? 113.839 147.715 147.069 1.00 40.60  ? 52  VAL   A CA  1 
ATOM   182  C C   . VAL   A 1 26  ? 113.420 146.252 147.054 1.00 41.95  ? 52  VAL   A C   1 
ATOM   183  O O   . VAL   A 1 26  ? 114.174 145.368 147.486 1.00 46.56  ? 52  VAL   A O   1 
ATOM   184  C CB  . VAL   A 1 26  ? 113.244 148.469 148.274 1.00 41.41  ? 52  VAL   A CB  1 
ATOM   185  C CG1 . VAL   A 1 26  ? 113.405 147.669 149.552 1.00 43.75  ? 52  VAL   A CG1 1 
ATOM   186  C CG2 . VAL   A 1 26  ? 113.903 149.822 148.431 1.00 46.51  ? 52  VAL   A CG2 1 
ATOM   187  N N   . THR   A 1 27  ? 112.217 145.969 146.556 1.00 39.50  ? 53  THR   A N   1 
ATOM   188  C CA  . THR   A 1 27  ? 111.761 144.586 146.479 1.00 39.47  ? 53  THR   A CA  1 
ATOM   189  C C   . THR   A 1 27  ? 112.647 143.765 145.551 1.00 42.29  ? 53  THR   A C   1 
ATOM   190  O O   . THR   A 1 27  ? 112.964 142.607 145.849 1.00 50.20  ? 53  THR   A O   1 
ATOM   191  C CB  . THR   A 1 27  ? 110.308 144.540 146.015 1.00 40.72  ? 53  THR   A CB  1 
ATOM   192  O OG1 . THR   A 1 27  ? 109.481 145.215 146.966 1.00 41.86  ? 53  THR   A OG1 1 
ATOM   193  C CG2 . THR   A 1 27  ? 109.839 143.105 145.873 1.00 46.79  ? 53  THR   A CG2 1 
ATOM   194  N N   . LEU   A 1 28  ? 113.052 144.341 144.421 1.00 40.01  ? 54  LEU   A N   1 
ATOM   195  C CA  . LEU   A 1 28  ? 113.943 143.631 143.510 1.00 39.96  ? 54  LEU   A CA  1 
ATOM   196  C C   . LEU   A 1 28  ? 115.299 143.379 144.154 1.00 39.92  ? 54  LEU   A C   1 
ATOM   197  O O   . LEU   A 1 28  ? 115.860 142.286 144.020 1.00 42.91  ? 54  LEU   A O   1 
ATOM   198  C CB  . LEU   A 1 28  ? 114.103 144.422 142.213 1.00 43.78  ? 54  LEU   A CB  1 
ATOM   199  C CG  . LEU   A 1 28  ? 115.140 143.934 141.199 1.00 44.03  ? 54  LEU   A CG  1 
ATOM   200  C CD1 . LEU   A 1 28  ? 114.912 142.485 140.835 1.00 45.28  ? 54  LEU   A CD1 1 
ATOM   201  C CD2 . LEU   A 1 28  ? 115.094 144.800 139.963 1.00 49.17  ? 54  LEU   A CD2 1 
ATOM   202  N N   . LEU   A 1 29  ? 115.843 144.373 144.852 1.00 38.26  ? 55  LEU   A N   1 
ATOM   203  C CA  . LEU   A 1 29  ? 117.155 144.227 145.467 1.00 36.11  ? 55  LEU   A CA  1 
ATOM   204  C C   . LEU   A 1 29  ? 117.135 143.395 146.741 1.00 40.00  ? 55  LEU   A C   1 
ATOM   205  O O   . LEU   A 1 29  ? 118.212 143.064 147.248 1.00 45.76  ? 55  LEU   A O   1 
ATOM   206  C CB  . LEU   A 1 29  ? 117.752 145.602 145.775 1.00 36.89  ? 55  LEU   A CB  1 
ATOM   207  C CG  . LEU   A 1 29  ? 118.341 146.386 144.600 1.00 40.26  ? 55  LEU   A CG  1 
ATOM   208  C CD1 . LEU   A 1 29  ? 118.617 147.819 144.996 1.00 41.53  ? 55  LEU   A CD1 1 
ATOM   209  C CD2 . LEU   A 1 29  ? 119.614 145.743 144.096 1.00 41.16  ? 55  LEU   A CD2 1 
ATOM   210  N N   . ASN   A 1 30  ? 115.955 143.052 147.269 1.00 37.47  ? 56  ASN   A N   1 
ATOM   211  C CA  . ASN   A 1 30  ? 115.833 142.214 148.458 1.00 32.92  ? 56  ASN   A CA  1 
ATOM   212  C C   . ASN   A 1 30  ? 115.034 140.942 148.193 1.00 35.26  ? 56  ASN   A C   1 
ATOM   213  O O   . ASN   A 1 30  ? 114.451 140.377 149.123 1.00 43.50  ? 56  ASN   A O   1 
ATOM   214  C CB  . ASN   A 1 30  ? 115.201 143.013 149.597 1.00 35.19  ? 56  ASN   A CB  1 
ATOM   215  C CG  . ASN   A 1 30  ? 116.082 144.150 150.059 1.00 40.10  ? 56  ASN   A CG  1 
ATOM   216  O OD1 . ASN   A 1 30  ? 116.812 144.024 151.038 1.00 43.68  ? 56  ASN   A OD1 1 
ATOM   217  N ND2 . ASN   A 1 30  ? 116.026 145.266 149.351 1.00 42.65  ? 56  ASN   A ND2 1 
ATOM   218  N N   . ARG   A 1 31  ? 114.994 140.473 146.951 1.00 31.63  ? 57  ARG   A N   1 
ATOM   219  C CA  . ARG   A 1 31  ? 114.268 139.251 146.648 1.00 33.59  ? 57  ARG   A CA  1 
ATOM   220  C C   . ARG   A 1 31  ? 115.061 138.036 147.133 1.00 37.66  ? 57  ARG   A C   1 
ATOM   221  O O   . ARG   A 1 31  ? 116.278 138.121 147.320 1.00 42.74  ? 57  ARG   A O   1 
ATOM   222  C CB  . ARG   A 1 31  ? 114.003 139.138 145.151 1.00 36.93  ? 57  ARG   A CB  1 
ATOM   223  C CG  . ARG   A 1 31  ? 115.253 138.997 144.297 1.00 39.43  ? 57  ARG   A CG  1 
ATOM   224  C CD  . ARG   A 1 31  ? 114.971 139.226 142.819 1.00 41.63  ? 57  ARG   A CD  1 
ATOM   225  N NE  . ARG   A 1 31  ? 115.068 138.000 142.037 1.00 41.09  ? 57  ARG   A NE  1 
ATOM   226  C CZ  . ARG   A 1 31  ? 115.159 137.950 140.715 1.00 42.83  ? 57  ARG   A CZ  1 
ATOM   227  N NH1 . ARG   A 1 31  ? 115.185 139.047 139.975 1.00 40.89  ? 57  ARG   A NH1 1 
ATOM   228  N NH2 . ARG   A 1 31  ? 115.231 136.765 140.116 1.00 46.52  ? 57  ARG   A NH2 1 
ATOM   229  N N   . PRO   A 1 32  ? 114.401 136.895 147.358 1.00 34.65  ? 58  PRO   A N   1 
ATOM   230  C CA  . PRO   A 1 32  ? 115.132 135.723 147.853 1.00 33.61  ? 58  PRO   A CA  1 
ATOM   231  C C   . PRO   A 1 32  ? 116.158 135.220 146.850 1.00 33.46  ? 58  PRO   A C   1 
ATOM   232  O O   . PRO   A 1 32  ? 115.986 135.340 145.637 1.00 39.61  ? 58  PRO   A O   1 
ATOM   233  C CB  . PRO   A 1 32  ? 114.029 134.684 148.082 1.00 36.86  ? 58  PRO   A CB  1 
ATOM   234  C CG  . PRO   A 1 32  ? 112.779 135.447 148.154 1.00 37.00  ? 58  PRO   A CG  1 
ATOM   235  C CD  . PRO   A 1 32  ? 112.957 136.619 147.264 1.00 36.29  ? 58  PRO   A CD  1 
ATOM   236  N N   . THR   A 1 33  ? 117.240 134.650 147.377 1.00 31.60  ? 59  THR   A N   1 
ATOM   237  C CA  . THR   A 1 33  ? 118.275 134.033 146.562 1.00 34.98  ? 59  THR   A CA  1 
ATOM   238  C C   . THR   A 1 33  ? 118.983 132.979 147.402 1.00 37.77  ? 59  THR   A C   1 
ATOM   239  O O   . THR   A 1 33  ? 119.027 133.077 148.630 1.00 39.91  ? 59  THR   A O   1 
ATOM   240  C CB  . THR   A 1 33  ? 119.276 135.071 146.041 1.00 39.84  ? 59  THR   A CB  1 
ATOM   241  O OG1 . THR   A 1 33  ? 118.571 136.156 145.430 1.00 40.33  ? 59  THR   A OG1 1 
ATOM   242  C CG2 . THR   A 1 33  ? 120.217 134.455 145.014 1.00 45.36  ? 59  THR   A CG2 1 
ATOM   243  N N   . ASP   A 1 34  ? 119.533 131.968 146.734 1.00 39.74  ? 60  ASP   A N   1 
ATOM   244  C CA  . ASP   A 1 34  ? 120.159 130.870 147.454 1.00 38.62  ? 60  ASP   A CA  1 
ATOM   245  C C   . ASP   A 1 34  ? 121.508 131.313 148.023 1.00 39.79  ? 60  ASP   A C   1 
ATOM   246  O O   . ASP   A 1 34  ? 122.179 132.163 147.429 1.00 43.16  ? 60  ASP   A O   1 
ATOM   247  C CB  . ASP   A 1 34  ? 120.355 129.663 146.543 1.00 42.08  ? 60  ASP   A CB  1 
ATOM   248  C CG  . ASP   A 1 34  ? 119.046 129.032 146.124 1.00 50.85  ? 60  ASP   A CG  1 
ATOM   249  O OD1 . ASP   A 1 34  ? 118.292 129.673 145.363 1.00 52.71  ? 60  ASP   A OD1 1 
ATOM   250  O OD2 . ASP   A 1 34  ? 118.771 127.893 146.558 1.00 55.58  ? 60  ASP   A OD2 1 
ATOM   251  N N   . PRO   A 1 35  ? 121.938 130.764 149.159 1.00 35.77  ? 61  PRO   A N   1 
ATOM   252  C CA  . PRO   A 1 35  ? 123.169 131.238 149.811 1.00 36.01  ? 61  PRO   A CA  1 
ATOM   253  C C   . PRO   A 1 35  ? 124.447 130.479 149.477 1.00 38.66  ? 61  PRO   A C   1 
ATOM   254  O O   . PRO   A 1 35  ? 125.493 130.822 150.035 1.00 43.25  ? 61  PRO   A O   1 
ATOM   255  C CB  . PRO   A 1 35  ? 122.825 131.035 151.287 1.00 38.02  ? 61  PRO   A CB  1 
ATOM   256  C CG  . PRO   A 1 35  ? 122.049 129.782 151.262 1.00 39.59  ? 61  PRO   A CG  1 
ATOM   257  C CD  . PRO   A 1 35  ? 121.190 129.863 150.056 1.00 38.45  ? 61  PRO   A CD  1 
ATOM   258  N N   . ALA   A 1 36  ? 124.410 129.473 148.604 1.00 38.39  ? 62  ALA   A N   1 
ATOM   259  C CA  . ALA   A 1 36  ? 125.509 128.512 148.535 1.00 41.26  ? 62  ALA   A CA  1 
ATOM   260  C C   . ALA   A 1 36  ? 126.788 129.133 147.972 1.00 43.45  ? 62  ALA   A C   1 
ATOM   261  O O   . ALA   A 1 36  ? 127.873 128.994 148.560 1.00 49.00  ? 62  ALA   A O   1 
ATOM   262  C CB  . ALA   A 1 36  ? 125.076 127.310 147.703 1.00 39.37  ? 62  ALA   A CB  1 
ATOM   263  N N   . SER   A 1 37  ? 126.682 129.816 146.829 1.00 37.89  ? 63  SER   A N   1 
ATOM   264  C CA  . SER   A 1 37  ? 127.870 130.357 146.174 1.00 38.34  ? 63  SER   A CA  1 
ATOM   265  C C   . SER   A 1 37  ? 128.563 131.389 147.054 1.00 41.20  ? 63  SER   A C   1 
ATOM   266  O O   . SER   A 1 37  ? 129.799 131.433 147.125 1.00 43.85  ? 63  SER   A O   1 
ATOM   267  C CB  . SER   A 1 37  ? 127.490 130.972 144.831 1.00 40.73  ? 63  SER   A CB  1 
ATOM   268  O OG  . SER   A 1 37  ? 128.622 131.541 144.202 1.00 43.95  ? 63  SER   A OG  1 
ATOM   269  N N   . LEU   A 1 38  ? 127.779 132.228 147.731 1.00 41.74  ? 64  LEU   A N   1 
ATOM   270  C CA  . LEU   A 1 38  ? 128.352 133.216 148.634 1.00 41.11  ? 64  LEU   A CA  1 
ATOM   271  C C   . LEU   A 1 38  ? 129.100 132.543 149.775 1.00 40.06  ? 64  LEU   A C   1 
ATOM   272  O O   . LEU   A 1 38  ? 130.163 133.015 150.193 1.00 44.01  ? 64  LEU   A O   1 
ATOM   273  C CB  . LEU   A 1 38  ? 127.244 134.121 149.169 1.00 40.49  ? 64  LEU   A CB  1 
ATOM   274  C CG  . LEU   A 1 38  ? 127.642 135.377 149.939 1.00 41.20  ? 64  LEU   A CG  1 
ATOM   275  C CD1 . LEU   A 1 38  ? 128.408 136.343 149.057 1.00 42.15  ? 64  LEU   A CD1 1 
ATOM   276  C CD2 . LEU   A 1 38  ? 126.405 136.040 150.508 1.00 40.63  ? 64  LEU   A CD2 1 
ATOM   277  N N   . ALA   A 1 39  ? 128.564 131.435 150.290 1.00 34.95  ? 65  ALA   A N   1 
ATOM   278  C CA  . ALA   A 1 39  ? 129.246 130.715 151.359 1.00 37.13  ? 65  ALA   A CA  1 
ATOM   279  C C   . ALA   A 1 39  ? 130.577 130.147 150.884 1.00 38.55  ? 65  ALA   A C   1 
ATOM   280  O O   . ALA   A 1 39  ? 131.587 130.228 151.598 1.00 43.47  ? 65  ALA   A O   1 
ATOM   281  C CB  . ALA   A 1 39  ? 128.350 129.601 151.889 1.00 37.66  ? 65  ALA   A CB  1 
ATOM   282  N N   . VAL   A 1 40  ? 130.600 129.570 149.682 1.00 36.43  ? 66  VAL   A N   1 
ATOM   283  C CA  . VAL   A 1 40  ? 131.852 129.029 149.158 1.00 37.82  ? 66  VAL   A CA  1 
ATOM   284  C C   . VAL   A 1 40  ? 132.876 130.142 148.969 1.00 41.54  ? 66  VAL   A C   1 
ATOM   285  O O   . VAL   A 1 40  ? 134.063 129.979 149.290 1.00 43.08  ? 66  VAL   A O   1 
ATOM   286  C CB  . VAL   A 1 40  ? 131.599 128.260 147.848 1.00 39.47  ? 66  VAL   A CB  1 
ATOM   287  C CG1 . VAL   A 1 40  ? 132.916 127.861 147.197 1.00 41.71  ? 66  VAL   A CG1 1 
ATOM   288  C CG2 . VAL   A 1 40  ? 130.750 127.035 148.115 1.00 41.52  ? 66  VAL   A CG2 1 
ATOM   289  N N   . PHE   A 1 41  ? 132.441 131.288 148.439 1.00 42.02  ? 67  PHE   A N   1 
ATOM   290  C CA  . PHE   A 1 41  ? 133.366 132.401 148.251 1.00 42.15  ? 67  PHE   A CA  1 
ATOM   291  C C   . PHE   A 1 41  ? 133.887 132.916 149.584 1.00 44.08  ? 67  PHE   A C   1 
ATOM   292  O O   . PHE   A 1 41  ? 135.067 133.266 149.700 1.00 49.91  ? 67  PHE   A O   1 
ATOM   293  C CB  . PHE   A 1 41  ? 132.692 133.532 147.483 1.00 43.74  ? 67  PHE   A CB  1 
ATOM   294  C CG  . PHE   A 1 41  ? 133.475 134.813 147.493 1.00 45.42  ? 67  PHE   A CG  1 
ATOM   295  C CD1 . PHE   A 1 41  ? 134.686 134.904 146.837 1.00 45.10  ? 67  PHE   A CD1 1 
ATOM   296  C CD2 . PHE   A 1 41  ? 132.996 135.926 148.154 1.00 46.53  ? 67  PHE   A CD2 1 
ATOM   297  C CE1 . PHE   A 1 41  ? 135.405 136.075 146.843 1.00 45.61  ? 67  PHE   A CE1 1 
ATOM   298  C CE2 . PHE   A 1 41  ? 133.711 137.102 148.160 1.00 47.59  ? 67  PHE   A CE2 1 
ATOM   299  C CZ  . PHE   A 1 41  ? 134.917 137.175 147.503 1.00 47.56  ? 67  PHE   A CZ  1 
ATOM   300  N N   . ARG   A 1 42  ? 133.020 132.981 150.597 1.00 40.39  ? 68  ARG   A N   1 
ATOM   301  C CA  . ARG   A 1 42  ? 133.459 133.382 151.929 1.00 41.21  ? 68  ARG   A CA  1 
ATOM   302  C C   . ARG   A 1 42  ? 134.535 132.442 152.448 1.00 39.93  ? 68  ARG   A C   1 
ATOM   303  O O   . ARG   A 1 42  ? 135.558 132.889 152.984 1.00 43.27  ? 68  ARG   A O   1 
ATOM   304  C CB  . ARG   A 1 42  ? 132.257 133.404 152.875 1.00 40.52  ? 68  ARG   A CB  1 
ATOM   305  C CG  . ARG   A 1 42  ? 132.557 133.681 154.353 1.00 40.44  ? 68  ARG   A CG  1 
ATOM   306  C CD  . ARG   A 1 42  ? 131.329 133.473 155.228 1.00 42.46  ? 68  ARG   A CD  1 
ATOM   307  N NE  . ARG   A 1 42  ? 130.794 132.118 155.142 1.00 40.79  ? 68  ARG   A NE  1 
ATOM   308  C CZ  . ARG   A 1 42  ? 131.285 131.060 155.774 1.00 37.83  ? 68  ARG   A CZ  1 
ATOM   309  N NH1 . ARG   A 1 42  ? 132.353 131.145 156.550 1.00 42.44  ? 68  ARG   A NH1 1 
ATOM   310  N NH2 . ARG   A 1 42  ? 130.693 129.882 155.618 1.00 36.66  ? 68  ARG   A NH2 1 
ATOM   311  N N   . PHE   A 1 43  ? 134.318 131.136 152.297 1.00 39.87  ? 69  PHE   A N   1 
ATOM   312  C CA  . PHE   A 1 43  ? 135.288 130.163 152.784 1.00 39.48  ? 69  PHE   A CA  1 
ATOM   313  C C   . PHE   A 1 43  ? 136.629 130.332 152.084 1.00 42.64  ? 69  PHE   A C   1 
ATOM   314  O O   . PHE   A 1 43  ? 137.684 130.370 152.733 1.00 48.41  ? 69  PHE   A O   1 
ATOM   315  C CB  . PHE   A 1 43  ? 134.745 128.750 152.581 1.00 38.78  ? 69  PHE   A CB  1 
ATOM   316  C CG  . PHE   A 1 43  ? 135.665 127.671 153.059 1.00 39.23  ? 69  PHE   A CG  1 
ATOM   317  C CD1 . PHE   A 1 43  ? 135.712 127.325 154.395 1.00 46.22  ? 69  PHE   A CD1 1 
ATOM   318  C CD2 . PHE   A 1 43  ? 136.469 126.990 152.171 1.00 39.29  ? 69  PHE   A CD2 1 
ATOM   319  C CE1 . PHE   A 1 43  ? 136.553 126.328 154.832 1.00 48.03  ? 69  PHE   A CE1 1 
ATOM   320  C CE2 . PHE   A 1 43  ? 137.309 125.995 152.603 1.00 38.98  ? 69  PHE   A CE2 1 
ATOM   321  C CZ  . PHE   A 1 43  ? 137.352 125.663 153.934 1.00 44.79  ? 69  PHE   A CZ  1 
ATOM   322  N N   . LEU   A 1 44  ? 136.605 130.453 150.756 1.00 43.25  ? 70  LEU   A N   1 
ATOM   323  C CA  . LEU   A 1 44  ? 137.857 130.579 150.017 1.00 43.81  ? 70  LEU   A CA  1 
ATOM   324  C C   . LEU   A 1 44  ? 138.579 131.875 150.363 1.00 45.11  ? 70  LEU   A C   1 
ATOM   325  O O   . LEU   A 1 44  ? 139.802 131.877 150.543 1.00 50.29  ? 70  LEU   A O   1 
ATOM   326  C CB  . LEU   A 1 44  ? 137.595 130.494 148.514 1.00 45.61  ? 70  LEU   A CB  1 
ATOM   327  C CG  . LEU   A 1 44  ? 137.121 129.140 147.984 1.00 45.33  ? 70  LEU   A CG  1 
ATOM   328  C CD1 . LEU   A 1 44  ? 136.704 129.260 146.534 1.00 46.73  ? 70  LEU   A CD1 1 
ATOM   329  C CD2 . LEU   A 1 44  ? 138.194 128.078 148.135 1.00 45.93  ? 70  LEU   A CD2 1 
ATOM   330  N N   . PHE   A 1 45  ? 137.844 132.982 150.480 1.00 42.65  ? 71  PHE   A N   1 
ATOM   331  C CA  . PHE   A 1 45  ? 138.476 134.256 150.803 1.00 44.32  ? 71  PHE   A CA  1 
ATOM   332  C C   . PHE   A 1 45  ? 139.106 134.220 152.188 1.00 45.30  ? 71  PHE   A C   1 
ATOM   333  O O   . PHE   A 1 45  ? 140.249 134.661 152.371 1.00 50.24  ? 71  PHE   A O   1 
ATOM   334  C CB  . PHE   A 1 45  ? 137.450 135.382 150.706 1.00 48.00  ? 71  PHE   A CB  1 
ATOM   335  C CG  . PHE   A 1 45  ? 138.015 136.743 150.974 1.00 48.52  ? 71  PHE   A CG  1 
ATOM   336  C CD1 . PHE   A 1 45  ? 138.877 137.337 150.074 1.00 48.74  ? 71  PHE   A CD1 1 
ATOM   337  C CD2 . PHE   A 1 45  ? 137.673 137.435 152.119 1.00 47.25  ? 71  PHE   A CD2 1 
ATOM   338  C CE1 . PHE   A 1 45  ? 139.394 138.588 150.316 1.00 49.77  ? 71  PHE   A CE1 1 
ATOM   339  C CE2 . PHE   A 1 45  ? 138.186 138.686 152.365 1.00 46.98  ? 71  PHE   A CE2 1 
ATOM   340  C CZ  . PHE   A 1 45  ? 139.048 139.264 151.465 1.00 48.48  ? 71  PHE   A CZ  1 
ATOM   341  N N   . GLY   A 1 46  ? 138.384 133.680 153.173 1.00 43.87  ? 72  GLY   A N   1 
ATOM   342  C CA  . GLY   A 1 46  ? 138.946 133.572 154.506 1.00 40.04  ? 72  GLY   A CA  1 
ATOM   343  C C   . GLY   A 1 46  ? 140.189 132.707 154.544 1.00 42.45  ? 72  GLY   A C   1 
ATOM   344  O O   . GLY   A 1 46  ? 141.191 133.075 155.160 1.00 49.18  ? 72  GLY   A O   1 
ATOM   345  N N   . PHE   A 1 47  ? 140.148 131.552 153.877 1.00 41.10  ? 73  PHE   A N   1 
ATOM   346  C CA  . PHE   A 1 47  ? 141.305 130.662 153.874 1.00 42.94  ? 73  PHE   A CA  1 
ATOM   347  C C   . PHE   A 1 47  ? 142.509 131.317 153.206 1.00 48.67  ? 73  PHE   A C   1 
ATOM   348  O O   . PHE   A 1 47  ? 143.640 131.218 153.705 1.00 52.68  ? 73  PHE   A O   1 
ATOM   349  C CB  . PHE   A 1 47  ? 140.943 129.354 153.173 1.00 42.93  ? 73  PHE   A CB  1 
ATOM   350  C CG  . PHE   A 1 47  ? 142.033 128.326 153.194 1.00 46.12  ? 73  PHE   A CG  1 
ATOM   351  C CD1 . PHE   A 1 47  ? 142.508 127.823 154.390 1.00 52.38  ? 73  PHE   A CD1 1 
ATOM   352  C CD2 . PHE   A 1 47  ? 142.559 127.839 152.017 1.00 45.91  ? 73  PHE   A CD2 1 
ATOM   353  C CE1 . PHE   A 1 47  ? 143.501 126.871 154.409 1.00 53.11  ? 73  PHE   A CE1 1 
ATOM   354  C CE2 . PHE   A 1 47  ? 143.550 126.886 152.031 1.00 50.32  ? 73  PHE   A CE2 1 
ATOM   355  C CZ  . PHE   A 1 47  ? 144.022 126.401 153.226 1.00 51.03  ? 73  PHE   A CZ  1 
ATOM   356  N N   . LEU   A 1 48  ? 142.290 131.992 152.076 1.00 48.19  ? 74  LEU   A N   1 
ATOM   357  C CA  . LEU   A 1 48  ? 143.403 132.629 151.382 1.00 46.27  ? 74  LEU   A CA  1 
ATOM   358  C C   . LEU   A 1 48  ? 144.005 133.755 152.212 1.00 45.84  ? 74  LEU   A C   1 
ATOM   359  O O   . LEU   A 1 48  ? 145.231 133.895 152.271 1.00 50.42  ? 74  LEU   A O   1 
ATOM   360  C CB  . LEU   A 1 48  ? 142.945 133.140 150.017 1.00 46.93  ? 74  LEU   A CB  1 
ATOM   361  C CG  . LEU   A 1 48  ? 142.580 132.071 148.982 1.00 48.49  ? 74  LEU   A CG  1 
ATOM   362  C CD1 . LEU   A 1 48  ? 141.975 132.720 147.752 1.00 52.02  ? 74  LEU   A CD1 1 
ATOM   363  C CD2 . LEU   A 1 48  ? 143.784 131.237 148.595 1.00 50.07  ? 74  LEU   A CD2 1 
ATOM   364  N N   . MET   A 1 49  ? 143.174 134.564 152.874 1.00 46.34  ? 75  MET   A N   1 
ATOM   365  C CA  . MET   A 1 49  ? 143.731 135.614 153.723 1.00 47.47  ? 75  MET   A CA  1 
ATOM   366  C C   . MET   A 1 49  ? 144.456 135.025 154.931 1.00 45.98  ? 75  MET   A C   1 
ATOM   367  O O   . MET   A 1 49  ? 145.463 135.582 155.387 1.00 48.56  ? 75  MET   A O   1 
ATOM   368  C CB  . MET   A 1 49  ? 142.636 136.584 154.167 1.00 48.01  ? 75  MET   A CB  1 
ATOM   369  C CG  . MET   A 1 49  ? 141.997 137.394 153.038 1.00 49.95  ? 75  MET   A CG  1 
ATOM   370  S SD  . MET   A 1 49  ? 143.135 138.294 151.965 1.00 62.84  ? 75  MET   A SD  1 
ATOM   371  C CE  . MET   A 1 49  ? 143.836 139.492 153.096 1.00 56.30  ? 75  MET   A CE  1 
ATOM   372  N N   . VAL   A 1 50  ? 143.965 133.899 155.457 1.00 43.47  ? 76  VAL   A N   1 
ATOM   373  C CA  . VAL   A 1 50  ? 144.666 133.217 156.542 1.00 42.15  ? 76  VAL   A CA  1 
ATOM   374  C C   . VAL   A 1 50  ? 146.055 132.800 156.085 1.00 48.36  ? 76  VAL   A C   1 
ATOM   375  O O   . VAL   A 1 50  ? 147.041 132.964 156.814 1.00 50.42  ? 76  VAL   A O   1 
ATOM   376  C CB  . VAL   A 1 50  ? 143.838 132.013 157.033 1.00 41.62  ? 76  VAL   A CB  1 
ATOM   377  C CG1 . VAL   A 1 50  ? 144.693 131.013 157.799 1.00 42.02  ? 76  VAL   A CG1 1 
ATOM   378  C CG2 . VAL   A 1 50  ? 142.700 132.482 157.912 1.00 44.34  ? 76  VAL   A CG2 1 
ATOM   379  N N   . LEU   A 1 51  ? 146.160 132.253 154.873 1.00 49.93  ? 77  LEU   A N   1 
ATOM   380  C CA  . LEU   A 1 51  ? 147.480 131.904 154.354 1.00 46.71  ? 77  LEU   A CA  1 
ATOM   381  C C   . LEU   A 1 51  ? 148.317 133.142 154.060 1.00 50.79  ? 77  LEU   A C   1 
ATOM   382  O O   . LEU   A 1 51  ? 149.550 133.080 154.115 1.00 51.94  ? 77  LEU   A O   1 
ATOM   383  C CB  . LEU   A 1 51  ? 147.352 131.061 153.086 1.00 45.83  ? 77  LEU   A CB  1 
ATOM   384  C CG  . LEU   A 1 51  ? 146.838 129.628 153.205 1.00 50.10  ? 77  LEU   A CG  1 
ATOM   385  C CD1 . LEU   A 1 51  ? 146.763 129.008 151.825 1.00 54.66  ? 77  LEU   A CD1 1 
ATOM   386  C CD2 . LEU   A 1 51  ? 147.715 128.784 154.116 1.00 52.93  ? 77  LEU   A CD2 1 
ATOM   387  N N   . ASP   A 1 52  ? 147.674 134.269 153.752 1.00 51.06  ? 78  ASP   A N   1 
ATOM   388  C CA  . ASP   A 1 52  ? 148.394 135.451 153.297 1.00 46.02  ? 78  ASP   A CA  1 
ATOM   389  C C   . ASP   A 1 52  ? 148.928 136.312 154.432 1.00 45.75  ? 78  ASP   A C   1 
ATOM   390  O O   . ASP   A 1 52  ? 149.884 137.062 154.212 1.00 49.61  ? 78  ASP   A O   1 
ATOM   391  C CB  . ASP   A 1 52  ? 147.478 136.304 152.419 1.00 51.06  ? 78  ASP   A CB  1 
ATOM   392  C CG  . ASP   A 1 52  ? 148.211 137.436 151.736 1.00 58.97  ? 78  ASP   A CG  1 
ATOM   393  O OD1 . ASP   A 1 52  ? 149.444 137.340 151.576 1.00 59.62  ? 78  ASP   A OD1 1 
ATOM   394  O OD2 . ASP   A 1 52  ? 147.554 138.427 151.359 1.00 63.10  ? 78  ASP   A OD2 1 
ATOM   395  N N   . ILE   A 1 53  ? 148.337 136.241 155.628 1.00 48.47  ? 79  ILE   A N   1 
ATOM   396  C CA  . ILE   A 1 53  ? 148.790 137.101 156.726 1.00 46.15  ? 79  ILE   A CA  1 
ATOM   397  C C   . ILE   A 1 53  ? 150.253 136.846 157.088 1.00 48.87  ? 79  ILE   A C   1 
ATOM   398  O O   . ILE   A 1 53  ? 150.997 137.822 157.264 1.00 53.64  ? 79  ILE   A O   1 
ATOM   399  C CB  . ILE   A 1 53  ? 147.839 136.975 157.927 1.00 43.77  ? 79  ILE   A CB  1 
ATOM   400  C CG1 . ILE   A 1 53  ? 146.535 137.722 157.640 1.00 50.11  ? 79  ILE   A CG1 1 
ATOM   401  C CG2 . ILE   A 1 53  ? 148.483 137.517 159.203 1.00 43.94  ? 79  ILE   A CG2 1 
ATOM   402  C CD1 . ILE   A 1 53  ? 145.371 137.303 158.517 1.00 51.31  ? 79  ILE   A CD1 1 
ATOM   403  N N   . PRO   A 1 54  ? 150.727 135.603 157.216 1.00 48.46  ? 80  PRO   A N   1 
ATOM   404  C CA  . PRO   A 1 54  ? 152.142 135.402 157.554 1.00 46.93  ? 80  PRO   A CA  1 
ATOM   405  C C   . PRO   A 1 54  ? 153.118 135.588 156.402 1.00 47.88  ? 80  PRO   A C   1 
ATOM   406  O O   . PRO   A 1 54  ? 154.326 135.459 156.630 1.00 51.33  ? 80  PRO   A O   1 
ATOM   407  C CB  . PRO   A 1 54  ? 152.170 133.948 158.054 1.00 49.37  ? 80  PRO   A CB  1 
ATOM   408  C CG  . PRO   A 1 54  ? 150.774 133.639 158.401 1.00 51.69  ? 80  PRO   A CG  1 
ATOM   409  C CD  . PRO   A 1 54  ? 149.993 134.336 157.355 1.00 51.16  ? 80  PRO   A CD  1 
ATOM   410  N N   . GLN   A 1 55  ? 152.656 135.895 155.189 1.00 47.95  ? 81  GLN   A N   1 
ATOM   411  C CA  . GLN   A 1 55  ? 153.519 135.960 154.014 1.00 48.79  ? 81  GLN   A CA  1 
ATOM   412  C C   . GLN   A 1 55  ? 153.672 137.375 153.472 1.00 53.11  ? 81  GLN   A C   1 
ATOM   413  O O   . GLN   A 1 55  ? 154.798 137.865 153.353 1.00 59.50  ? 81  GLN   A O   1 
ATOM   414  C CB  . GLN   A 1 55  ? 152.975 135.041 152.916 1.00 52.71  ? 81  GLN   A CB  1 
ATOM   415  C CG  . GLN   A 1 55  ? 153.137 133.566 153.210 1.00 56.15  ? 81  GLN   A CG  1 
ATOM   416  C CD  . GLN   A 1 55  ? 152.709 132.700 152.048 1.00 59.56  ? 81  GLN   A CD  1 
ATOM   417  O OE1 . GLN   A 1 55  ? 152.760 133.122 150.895 1.00 64.54  ? 81  GLN   A OE1 1 
ATOM   418  N NE2 . GLN   A 1 55  ? 152.278 131.482 152.345 1.00 58.20  ? 81  GLN   A NE2 1 
ATOM   419  N N   . GLU   A 1 56  ? 152.570 138.053 153.150 1.00 50.56  ? 82  GLU   A N   1 
ATOM   420  C CA  . GLU   A 1 56  ? 152.629 139.365 152.515 1.00 53.41  ? 82  GLU   A CA  1 
ATOM   421  C C   . GLU   A 1 56  ? 152.403 140.514 153.482 1.00 54.28  ? 82  GLU   A C   1 
ATOM   422  O O   . GLU   A 1 56  ? 152.995 141.581 153.297 1.00 57.68  ? 82  GLU   A O   1 
ATOM   423  C CB  . GLU   A 1 56  ? 151.596 139.455 151.389 1.00 57.71  ? 82  GLU   A CB  1 
ATOM   424  C CG  . GLU   A 1 56  ? 151.779 140.659 150.477 1.00 61.64  ? 82  GLU   A CG  1 
ATOM   425  C CD  . GLU   A 1 56  ? 150.779 140.687 149.341 1.00 66.40  ? 82  GLU   A CD  1 
ATOM   426  O OE1 . GLU   A 1 56  ? 150.059 139.684 149.152 1.00 68.06  ? 82  GLU   A OE1 1 
ATOM   427  O OE2 . GLU   A 1 56  ? 150.711 141.716 148.637 1.00 65.31  ? 82  GLU   A OE2 1 
ATOM   428  N N   . ARG   A 1 57  ? 151.563 140.335 154.502 1.00 50.00  ? 83  ARG   A N   1 
ATOM   429  C CA  . ARG   A 1 57  ? 151.375 141.399 155.481 1.00 48.87  ? 83  ARG   A CA  1 
ATOM   430  C C   . ARG   A 1 57  ? 152.655 141.665 156.257 1.00 55.30  ? 83  ARG   A C   1 
ATOM   431  O O   . ARG   A 1 57  ? 152.891 142.796 156.696 1.00 56.84  ? 83  ARG   A O   1 
ATOM   432  C CB  . ARG   A 1 57  ? 150.242 141.044 156.441 1.00 50.60  ? 83  ARG   A CB  1 
ATOM   433  C CG  . ARG   A 1 57  ? 148.871 140.902 155.793 1.00 55.37  ? 83  ARG   A CG  1 
ATOM   434  C CD  . ARG   A 1 57  ? 148.267 142.242 155.399 1.00 55.65  ? 83  ARG   A CD  1 
ATOM   435  N NE  . ARG   A 1 57  ? 148.736 142.707 154.098 1.00 55.32  ? 83  ARG   A NE  1 
ATOM   436  C CZ  . ARG   A 1 57  ? 148.267 142.294 152.927 1.00 55.04  ? 83  ARG   A CZ  1 
ATOM   437  N NH1 . ARG   A 1 57  ? 147.320 141.373 152.839 1.00 54.62  ? 83  ARG   A NH1 1 
ATOM   438  N NH2 . ARG   A 1 57  ? 148.765 142.818 151.811 1.00 52.69  ? 83  ARG   A NH2 1 
ATOM   439  N N   . GLY   A 1 58  ? 153.479 140.642 156.446 1.00 56.07  ? 84  GLY   A N   1 
ATOM   440  C CA  . GLY   A 1 58  ? 154.786 140.791 157.036 1.00 54.66  ? 84  GLY   A CA  1 
ATOM   441  C C   . GLY   A 1 58  ? 154.903 140.362 158.478 1.00 53.32  ? 84  GLY   A C   1 
ATOM   442  O O   . GLY   A 1 58  ? 155.738 140.916 159.200 1.00 59.17  ? 84  GLY   A O   1 
ATOM   443  N N   . LEU   A 1 59  ? 154.101 139.394 158.924 1.00 47.31  ? 85  LEU   A N   1 
ATOM   444  C CA  . LEU   A 1 59  ? 154.189 138.970 160.316 1.00 49.34  ? 85  LEU   A CA  1 
ATOM   445  C C   . LEU   A 1 59  ? 155.484 138.218 160.585 1.00 52.94  ? 85  LEU   A C   1 
ATOM   446  O O   . LEU   A 1 59  ? 155.995 138.252 161.710 1.00 55.94  ? 85  LEU   A O   1 
ATOM   447  C CB  . LEU   A 1 59  ? 152.980 138.111 160.679 1.00 47.60  ? 85  LEU   A CB  1 
ATOM   448  C CG  . LEU   A 1 59  ? 152.857 137.619 162.122 1.00 46.77  ? 85  LEU   A CG  1 
ATOM   449  C CD1 . LEU   A 1 59  ? 152.854 138.768 163.110 1.00 45.85  ? 85  LEU   A CD1 1 
ATOM   450  C CD2 . LEU   A 1 59  ? 151.598 136.794 162.273 1.00 46.71  ? 85  LEU   A CD2 1 
ATOM   451  N N   . SER   A 1 60  ? 156.031 137.539 159.576 1.00 50.21  ? 86  SER   A N   1 
ATOM   452  C CA  . SER   A 1 60  ? 157.316 136.873 159.755 1.00 52.10  ? 86  SER   A CA  1 
ATOM   453  C C   . SER   A 1 60  ? 158.445 137.883 159.906 1.00 54.28  ? 86  SER   A C   1 
ATOM   454  O O   . SER   A 1 60  ? 159.377 137.668 160.689 1.00 56.30  ? 86  SER   A O   1 
ATOM   455  C CB  . SER   A 1 60  ? 157.588 135.940 158.578 1.00 52.43  ? 86  SER   A CB  1 
ATOM   456  O OG  . SER   A 1 60  ? 157.590 136.653 157.356 1.00 54.55  ? 86  SER   A OG  1 
ATOM   457  N N   . SER   A 1 61  ? 158.377 138.989 159.167 1.00 55.09  ? 87  SER   A N   1 
ATOM   458  C CA  . SER   A 1 61  ? 159.408 140.018 159.168 1.00 54.54  ? 87  SER   A CA  1 
ATOM   459  C C   . SER   A 1 61  ? 159.081 141.183 160.091 1.00 53.02  ? 87  SER   A C   1 
ATOM   460  O O   . SER   A 1 61  ? 159.795 142.189 160.073 1.00 57.36  ? 87  SER   A O   1 
ATOM   461  C CB  . SER   A 1 61  ? 159.626 140.535 157.746 1.00 54.87  ? 87  SER   A CB  1 
ATOM   462  O OG  . SER   A 1 61  ? 160.674 141.488 157.703 1.00 59.82  ? 87  SER   A OG  1 
ATOM   463  N N   . LEU   A 1 62  ? 158.022 141.077 160.893 1.00 51.61  ? 88  LEU   A N   1 
ATOM   464  C CA  . LEU   A 1 62  ? 157.591 142.202 161.712 1.00 51.39  ? 88  LEU   A CA  1 
ATOM   465  C C   . LEU   A 1 62  ? 158.598 142.562 162.795 1.00 52.90  ? 88  LEU   A C   1 
ATOM   466  O O   . LEU   A 1 62  ? 158.558 143.686 163.306 1.00 55.27  ? 88  LEU   A O   1 
ATOM   467  C CB  . LEU   A 1 62  ? 156.244 141.879 162.352 1.00 48.09  ? 88  LEU   A CB  1 
ATOM   468  C CG  . LEU   A 1 62  ? 155.473 143.023 162.999 1.00 48.27  ? 88  LEU   A CG  1 
ATOM   469  C CD1 . LEU   A 1 62  ? 154.882 143.940 161.948 1.00 50.78  ? 88  LEU   A CD1 1 
ATOM   470  C CD2 . LEU   A 1 62  ? 154.386 142.453 163.885 1.00 49.49  ? 88  LEU   A CD2 1 
ATOM   471  N N   . ASP   A 1 63  ? 159.501 141.650 163.154 1.00 52.45  ? 89  ASP   A N   1 
ATOM   472  C CA  . ASP   A 1 63  ? 160.467 141.927 164.207 1.00 53.94  ? 89  ASP   A CA  1 
ATOM   473  C C   . ASP   A 1 63  ? 161.655 142.748 163.726 1.00 58.44  ? 89  ASP   A C   1 
ATOM   474  O O   . ASP   A 1 63  ? 162.405 143.257 164.566 1.00 63.49  ? 89  ASP   A O   1 
ATOM   475  C CB  . ASP   A 1 63  ? 160.970 140.618 164.816 1.00 59.53  ? 89  ASP   A CB  1 
ATOM   476  C CG  . ASP   A 1 63  ? 161.736 139.772 163.825 1.00 67.43  ? 89  ASP   A CG  1 
ATOM   477  O OD1 . ASP   A 1 63  ? 161.412 139.828 162.620 1.00 69.09  ? 89  ASP   A OD1 1 
ATOM   478  O OD2 . ASP   A 1 63  ? 162.663 139.050 164.248 1.00 69.44  ? 89  ASP   A OD2 1 
ATOM   479  N N   . ARG   A 1 64  ? 161.844 142.886 162.412 1.00 57.92  ? 90  ARG   A N   1 
ATOM   480  C CA  . ARG   A 1 64  ? 162.909 143.703 161.843 1.00 56.77  ? 90  ARG   A CA  1 
ATOM   481  C C   . ARG   A 1 64  ? 162.370 144.873 161.030 1.00 55.16  ? 90  ARG   A C   1 
ATOM   482  O O   . ARG   A 1 64  ? 163.137 145.506 160.296 1.00 59.39  ? 90  ARG   A O   1 
ATOM   483  C CB  . ARG   A 1 64  ? 163.831 142.840 160.977 1.00 58.24  ? 90  ARG   A CB  1 
ATOM   484  C CG  . ARG   A 1 64  ? 163.136 142.119 159.831 1.00 64.07  ? 90  ARG   A CG  1 
ATOM   485  C CD  . ARG   A 1 64  ? 164.108 141.252 159.045 1.00 73.78  ? 90  ARG   A CD  1 
ATOM   486  N NE  . ARG   A 1 64  ? 164.645 140.158 159.847 1.00 82.15  ? 90  ARG   A NE  1 
ATOM   487  C CZ  . ARG   A 1 64  ? 165.497 139.239 159.408 1.00 85.59  ? 90  ARG   A CZ  1 
ATOM   488  N NH1 . ARG   A 1 64  ? 165.945 139.242 158.161 1.00 84.13  ? 90  ARG   A NH1 1 
ATOM   489  N NH2 . ARG   A 1 64  ? 165.910 138.288 160.242 1.00 81.16  ? 90  ARG   A NH2 1 
ATOM   490  N N   . LYS   A 1 65  ? 161.077 145.176 161.140 1.00 52.16  ? 91  LYS   A N   1 
ATOM   491  C CA  . LYS   A 1 65  ? 160.454 146.332 160.509 1.00 49.62  ? 91  LYS   A CA  1 
ATOM   492  C C   . LYS   A 1 65  ? 160.023 147.384 161.512 1.00 50.05  ? 91  LYS   A C   1 
ATOM   493  O O   . LYS   A 1 65  ? 160.210 148.576 161.262 1.00 58.07  ? 91  LYS   A O   1 
ATOM   494  C CB  . LYS   A 1 65  ? 159.237 145.888 159.689 1.00 52.12  ? 91  LYS   A CB  1 
ATOM   495  C CG  . LYS   A 1 65  ? 158.444 147.020 159.053 1.00 58.16  ? 91  LYS   A CG  1 
ATOM   496  C CD  . LYS   A 1 65  ? 157.458 146.490 158.028 1.00 63.21  ? 91  LYS   A CD  1 
ATOM   497  C CE  . LYS   A 1 65  ? 156.606 147.606 157.442 1.00 64.16  ? 91  LYS   A CE  1 
ATOM   498  N NZ  . LYS   A 1 65  ? 157.415 148.616 156.703 1.00 63.78  ? 91  LYS   A NZ  1 
ATOM   499  N N   . TYR   A 1 66  ? 159.453 146.966 162.643 1.00 49.19  ? 92  TYR   A N   1 
ATOM   500  C CA  . TYR   A 1 66  ? 159.041 147.861 163.717 1.00 52.65  ? 92  TYR   A CA  1 
ATOM   501  C C   . TYR   A 1 66  ? 159.890 147.653 164.966 1.00 56.32  ? 92  TYR   A C   1 
ATOM   502  O O   . TYR   A 1 66  ? 159.389 147.745 166.089 1.00 60.79  ? 92  TYR   A O   1 
ATOM   503  C CB  . TYR   A 1 66  ? 157.561 147.663 164.043 1.00 52.49  ? 92  TYR   A CB  1 
ATOM   504  C CG  . TYR   A 1 66  ? 156.627 148.042 162.922 1.00 52.67  ? 92  TYR   A CG  1 
ATOM   505  C CD1 . TYR   A 1 66  ? 156.190 149.347 162.772 1.00 52.95  ? 92  TYR   A CD1 1 
ATOM   506  C CD2 . TYR   A 1 66  ? 156.177 147.096 162.018 1.00 56.58  ? 92  TYR   A CD2 1 
ATOM   507  C CE1 . TYR   A 1 66  ? 155.337 149.700 161.751 1.00 55.91  ? 92  TYR   A CE1 1 
ATOM   508  C CE2 . TYR   A 1 66  ? 155.321 147.439 160.994 1.00 60.29  ? 92  TYR   A CE2 1 
ATOM   509  C CZ  . TYR   A 1 66  ? 154.905 148.743 160.865 1.00 60.49  ? 92  TYR   A CZ  1 
ATOM   510  O OH  . TYR   A 1 66  ? 154.052 149.092 159.845 1.00 62.78  ? 92  TYR   A OH  1 
ATOM   511  N N   . LEU   A 1 67  ? 161.175 147.361 164.781 1.00 55.77  ? 93  LEU   A N   1 
ATOM   512  C CA  . LEU   A 1 67  ? 162.058 147.110 165.910 1.00 58.66  ? 93  LEU   A CA  1 
ATOM   513  C C   . LEU   A 1 67  ? 162.135 148.335 166.811 1.00 63.01  ? 93  LEU   A C   1 
ATOM   514  O O   . LEU   A 1 67  ? 162.256 149.468 166.340 1.00 68.21  ? 93  LEU   A O   1 
ATOM   515  C CB  . LEU   A 1 67  ? 163.451 146.733 165.407 1.00 60.36  ? 93  LEU   A CB  1 
ATOM   516  C CG  . LEU   A 1 67  ? 164.537 146.446 166.445 1.00 65.79  ? 93  LEU   A CG  1 
ATOM   517  C CD1 . LEU   A 1 67  ? 164.121 145.336 167.397 1.00 68.32  ? 93  LEU   A CD1 1 
ATOM   518  C CD2 . LEU   A 1 67  ? 165.832 146.085 165.742 1.00 66.36  ? 93  LEU   A CD2 1 
ATOM   519  N N   . ASP   A 1 68  ? 162.064 148.099 168.117 1.00 66.38  ? 94  ASP   A N   1 
ATOM   520  C CA  . ASP   A 1 68  ? 162.074 149.194 169.074 1.00 69.03  ? 94  ASP   A CA  1 
ATOM   521  C C   . ASP   A 1 68  ? 163.465 149.805 169.173 1.00 70.64  ? 94  ASP   A C   1 
ATOM   522  O O   . ASP   A 1 68  ? 164.477 149.102 169.105 1.00 71.63  ? 94  ASP   A O   1 
ATOM   523  C CB  . ASP   A 1 68  ? 161.617 148.701 170.446 1.00 72.11  ? 94  ASP   A CB  1 
ATOM   524  C CG  . ASP   A 1 68  ? 160.218 148.118 170.419 1.00 74.51  ? 94  ASP   A CG  1 
ATOM   525  O OD1 . ASP   A 1 68  ? 159.402 148.566 169.587 1.00 72.17  ? 94  ASP   A OD1 1 
ATOM   526  O OD2 . ASP   A 1 68  ? 159.935 147.211 171.229 1.00 73.50  ? 94  ASP   A OD2 1 
ATOM   527  N N   . GLY   A 1 69  ? 163.508 151.127 169.326 1.00 70.67  ? 95  GLY   A N   1 
ATOM   528  C CA  . GLY   A 1 69  ? 164.747 151.857 169.456 1.00 75.68  ? 95  GLY   A CA  1 
ATOM   529  C C   . GLY   A 1 69  ? 165.384 152.265 168.145 1.00 77.09  ? 95  GLY   A C   1 
ATOM   530  O O   . GLY   A 1 69  ? 166.265 153.132 168.145 1.00 75.76  ? 95  GLY   A O   1 
ATOM   531  N N   . LEU   A 1 70  ? 164.960 151.675 167.032 1.00 71.03  ? 96  LEU   A N   1 
ATOM   532  C CA  . LEU   A 1 70  ? 165.488 152.039 165.727 1.00 67.29  ? 96  LEU   A CA  1 
ATOM   533  C C   . LEU   A 1 70  ? 164.764 153.267 165.198 1.00 71.93  ? 96  LEU   A C   1 
ATOM   534  O O   . LEU   A 1 70  ? 163.539 153.375 165.300 1.00 72.89  ? 96  LEU   A O   1 
ATOM   535  C CB  . LEU   A 1 70  ? 165.331 150.876 164.749 1.00 67.71  ? 96  LEU   A CB  1 
ATOM   536  C CG  . LEU   A 1 70  ? 165.949 151.032 163.358 1.00 70.90  ? 96  LEU   A CG  1 
ATOM   537  C CD1 . LEU   A 1 70  ? 167.466 151.118 163.436 1.00 72.92  ? 96  LEU   A CD1 1 
ATOM   538  C CD2 . LEU   A 1 70  ? 165.522 149.882 162.465 1.00 69.46  ? 96  LEU   A CD2 1 
ATOM   539  N N   . ASP   A 1 71  ? 165.533 154.192 164.628 1.00 74.26  ? 97  ASP   A N   1 
ATOM   540  C CA  . ASP   A 1 71  ? 164.995 155.420 164.045 1.00 70.65  ? 97  ASP   A CA  1 
ATOM   541  C C   . ASP   A 1 71  ? 164.898 155.231 162.535 1.00 62.11  ? 97  ASP   A C   1 
ATOM   542  O O   . ASP   A 1 71  ? 165.917 155.103 161.850 1.00 57.44  ? 97  ASP   A O   1 
ATOM   543  C CB  . ASP   A 1 71  ? 165.849 156.636 164.409 1.00 65.38  ? 97  ASP   A CB  1 
ATOM   544  C CG  . ASP   A 1 71  ? 167.330 156.420 164.165 1.00 66.10  ? 97  ASP   A CG  1 
ATOM   545  O OD1 . ASP   A 1 71  ? 167.716 155.293 163.792 1.00 67.26  ? 97  ASP   A OD1 1 
ATOM   546  O OD2 . ASP   A 1 71  ? 168.110 157.376 164.359 1.00 67.17  ? 97  ASP   A OD2 1 
ATOM   547  N N   . VAL   A 1 72  ? 163.665 155.191 162.027 1.00 54.11  ? 98  VAL   A N   1 
ATOM   548  C CA  . VAL   A 1 72  ? 163.380 155.046 160.608 1.00 47.71  ? 98  VAL   A CA  1 
ATOM   549  C C   . VAL   A 1 72  ? 162.318 156.075 160.248 1.00 49.76  ? 98  VAL   A C   1 
ATOM   550  O O   . VAL   A 1 72  ? 161.556 156.535 161.100 1.00 53.46  ? 98  VAL   A O   1 
ATOM   551  C CB  . VAL   A 1 72  ? 162.901 153.620 160.246 1.00 53.03  ? 98  VAL   A CB  1 
ATOM   552  C CG1 . VAL   A 1 72  ? 163.030 153.345 158.744 1.00 52.05  ? 98  VAL   A CG1 1 
ATOM   553  C CG2 . VAL   A 1 72  ? 163.663 152.569 161.059 1.00 60.72  ? 98  VAL   A CG2 1 
ATOM   554  N N   . CYS   A 1 73  ? 162.279 156.440 158.968 1.00 52.43  ? 99  CYS   A N   1 
ATOM   555  C CA  . CYS   A 1 73  ? 161.317 157.410 158.461 1.00 48.69  ? 99  CYS   A CA  1 
ATOM   556  C C   . CYS   A 1 73  ? 160.086 156.677 157.942 1.00 47.75  ? 99  CYS   A C   1 
ATOM   557  O O   . CYS   A 1 73  ? 160.184 155.877 157.007 1.00 46.15  ? 99  CYS   A O   1 
ATOM   558  C CB  . CYS   A 1 73  ? 161.939 158.261 157.357 1.00 44.27  ? 99  CYS   A CB  1 
ATOM   559  S SG  . CYS   A 1 73  ? 163.407 159.175 157.857 1.00 59.54  ? 99  CYS   A SG  1 
ATOM   560  N N   . ARG   A 1 74  ? 158.935 156.956 158.547 1.00 46.37  ? 100 ARG   A N   1 
ATOM   561  C CA  . ARG   A 1 74  ? 157.677 156.336 158.166 1.00 45.38  ? 100 ARG   A CA  1 
ATOM   562  C C   . ARG   A 1 74  ? 156.965 157.200 157.137 1.00 44.73  ? 100 ARG   A C   1 
ATOM   563  O O   . ARG   A 1 74  ? 157.202 158.407 157.042 1.00 43.05  ? 100 ARG   A O   1 
ATOM   564  C CB  . ARG   A 1 74  ? 156.767 156.143 159.383 1.00 50.74  ? 100 ARG   A CB  1 
ATOM   565  C CG  . ARG   A 1 74  ? 157.386 155.387 160.548 1.00 52.22  ? 100 ARG   A CG  1 
ATOM   566  C CD  . ARG   A 1 74  ? 157.593 153.918 160.239 1.00 50.52  ? 100 ARG   A CD  1 
ATOM   567  N NE  . ARG   A 1 74  ? 158.330 153.257 161.309 1.00 49.71  ? 100 ARG   A NE  1 
ATOM   568  C CZ  . ARG   A 1 74  ? 158.762 152.005 161.273 1.00 47.60  ? 100 ARG   A CZ  1 
ATOM   569  N NH1 . ARG   A 1 74  ? 158.540 151.221 160.231 1.00 53.91  ? 100 ARG   A NH1 1 
ATOM   570  N NH2 . ARG   A 1 74  ? 159.441 151.526 162.311 1.00 43.64  ? 100 ARG   A NH2 1 
ATOM   571  N N   . PHE   A 1 75  ? 156.078 156.568 156.370 1.00 43.86  ? 101 PHE   A N   1 
ATOM   572  C CA  . PHE   A 1 75  ? 155.284 157.234 155.338 1.00 41.59  ? 101 PHE   A CA  1 
ATOM   573  C C   . PHE   A 1 75  ? 153.814 156.873 155.518 1.00 45.53  ? 101 PHE   A C   1 
ATOM   574  O O   . PHE   A 1 75  ? 153.257 156.098 154.733 1.00 49.30  ? 101 PHE   A O   1 
ATOM   575  C CB  . PHE   A 1 75  ? 155.760 156.839 153.939 1.00 41.32  ? 101 PHE   A CB  1 
ATOM   576  C CG  . PHE   A 1 75  ? 157.214 157.129 153.674 1.00 43.15  ? 101 PHE   A CG  1 
ATOM   577  C CD1 . PHE   A 1 75  ? 157.792 158.325 154.051 1.00 45.03  ? 101 PHE   A CD1 1 
ATOM   578  C CD2 . PHE   A 1 75  ? 158.001 156.196 153.035 1.00 44.51  ? 101 PHE   A CD2 1 
ATOM   579  C CE1 . PHE   A 1 75  ? 159.121 158.575 153.800 1.00 40.08  ? 101 PHE   A CE1 1 
ATOM   580  C CE2 . PHE   A 1 75  ? 159.329 156.444 152.783 1.00 41.73  ? 101 PHE   A CE2 1 
ATOM   581  C CZ  . PHE   A 1 75  ? 159.888 157.634 153.161 1.00 36.94  ? 101 PHE   A CZ  1 
ATOM   582  N N   . PRO   A 1 76  ? 153.151 157.420 156.537 1.00 45.28  ? 102 PRO   A N   1 
ATOM   583  C CA  . PRO   A 1 76  ? 151.722 157.157 156.705 1.00 43.87  ? 102 PRO   A CA  1 
ATOM   584  C C   . PRO   A 1 76  ? 150.873 158.158 155.943 1.00 45.77  ? 102 PRO   A C   1 
ATOM   585  O O   . PRO   A 1 76  ? 151.308 159.261 155.610 1.00 51.19  ? 102 PRO   A O   1 
ATOM   586  C CB  . PRO   A 1 76  ? 151.525 157.302 158.220 1.00 45.53  ? 102 PRO   A CB  1 
ATOM   587  C CG  . PRO   A 1 76  ? 152.630 158.196 158.679 1.00 44.24  ? 102 PRO   A CG  1 
ATOM   588  C CD  . PRO   A 1 76  ? 153.628 158.355 157.569 1.00 46.15  ? 102 PRO   A CD  1 
ATOM   589  N N   . LEU   A 1 77  ? 149.639 157.743 155.648 1.00 44.40  ? 103 LEU   A N   1 
ATOM   590  C CA  . LEU   A 1 77  ? 148.730 158.625 154.924 1.00 46.77  ? 103 LEU   A CA  1 
ATOM   591  C C   . LEU   A 1 77  ? 148.430 159.875 155.737 1.00 53.07  ? 103 LEU   A C   1 
ATOM   592  O O   . LEU   A 1 77  ? 148.409 160.987 155.195 1.00 60.00  ? 103 LEU   A O   1 
ATOM   593  C CB  . LEU   A 1 77  ? 147.439 157.887 154.574 1.00 49.56  ? 103 LEU   A CB  1 
ATOM   594  C CG  . LEU   A 1 77  ? 146.784 158.272 153.244 1.00 54.44  ? 103 LEU   A CG  1 
ATOM   595  C CD1 . LEU   A 1 77  ? 145.597 157.370 152.967 1.00 54.72  ? 103 LEU   A CD1 1 
ATOM   596  C CD2 . LEU   A 1 77  ? 146.353 159.724 153.219 1.00 54.04  ? 103 LEU   A CD2 1 
ATOM   597  N N   . LEU   A 1 78  ? 148.202 159.712 157.036 1.00 52.66  ? 104 LEU   A N   1 
ATOM   598  C CA  . LEU   A 1 78  ? 148.036 160.816 157.968 1.00 55.49  ? 104 LEU   A CA  1 
ATOM   599  C C   . LEU   A 1 78  ? 149.240 160.868 158.895 1.00 57.30  ? 104 LEU   A C   1 
ATOM   600  O O   . LEU   A 1 78  ? 149.687 159.835 159.403 1.00 63.46  ? 104 LEU   A O   1 
ATOM   601  C CB  . LEU   A 1 78  ? 146.759 160.664 158.797 1.00 57.57  ? 104 LEU   A CB  1 
ATOM   602  C CG  . LEU   A 1 78  ? 145.436 161.039 158.129 1.00 63.41  ? 104 LEU   A CG  1 
ATOM   603  C CD1 . LEU   A 1 78  ? 145.020 159.998 157.102 1.00 61.66  ? 104 LEU   A CD1 1 
ATOM   604  C CD2 . LEU   A 1 78  ? 144.355 161.221 159.181 1.00 63.81  ? 104 LEU   A CD2 1 
ATOM   605  N N   . ASP   A 1 79  ? 149.764 162.073 159.111 1.00 57.96  ? 105 ASP   A N   1 
ATOM   606  C CA  . ASP   A 1 79  ? 150.883 162.234 160.030 1.00 63.50  ? 105 ASP   A CA  1 
ATOM   607  C C   . ASP   A 1 79  ? 150.514 161.860 161.460 1.00 60.04  ? 105 ASP   A C   1 
ATOM   608  O O   . ASP   A 1 79  ? 151.407 161.568 162.261 1.00 57.16  ? 105 ASP   A O   1 
ATOM   609  C CB  . ASP   A 1 79  ? 151.392 163.674 159.987 1.00 68.35  ? 105 ASP   A CB  1 
ATOM   610  C CG  . ASP   A 1 79  ? 151.810 164.102 158.595 1.00 72.01  ? 105 ASP   A CG  1 
ATOM   611  O OD1 . ASP   A 1 79  ? 152.182 163.224 157.788 1.00 69.92  ? 105 ASP   A OD1 1 
ATOM   612  O OD2 . ASP   A 1 79  ? 151.766 165.317 158.306 1.00 68.81  ? 105 ASP   A OD2 1 
ATOM   613  N N   . ALA   A 1 80  ? 149.223 161.864 161.799 1.00 62.76  ? 106 ALA   A N   1 
ATOM   614  C CA  . ALA   A 1 80  ? 148.812 161.527 163.156 1.00 65.15  ? 106 ALA   A CA  1 
ATOM   615  C C   . ALA   A 1 80  ? 149.094 160.066 163.479 1.00 64.19  ? 106 ALA   A C   1 
ATOM   616  O O   . ALA   A 1 80  ? 149.460 159.740 164.614 1.00 66.97  ? 106 ALA   A O   1 
ATOM   617  C CB  . ALA   A 1 80  ? 147.329 161.840 163.346 1.00 65.59  ? 106 ALA   A CB  1 
ATOM   618  N N   . LEU   A 1 81  ? 148.912 159.171 162.508 1.00 60.53  ? 107 LEU   A N   1 
ATOM   619  C CA  . LEU   A 1 81  ? 149.139 157.752 162.754 1.00 59.17  ? 107 LEU   A CA  1 
ATOM   620  C C   . LEU   A 1 81  ? 150.599 157.495 163.097 1.00 63.10  ? 107 LEU   A C   1 
ATOM   621  O O   . LEU   A 1 81  ? 151.505 158.026 162.449 1.00 64.20  ? 107 LEU   A O   1 
ATOM   622  C CB  . LEU   A 1 81  ? 148.736 156.923 161.533 1.00 51.74  ? 107 LEU   A CB  1 
ATOM   623  C CG  . LEU   A 1 81  ? 147.246 156.698 161.262 1.00 55.82  ? 107 LEU   A CG  1 
ATOM   624  C CD1 . LEU   A 1 81  ? 147.066 155.902 159.986 1.00 52.49  ? 107 LEU   A CD1 1 
ATOM   625  C CD2 . LEU   A 1 81  ? 146.565 155.986 162.419 1.00 57.37  ? 107 LEU   A CD2 1 
ATOM   626  N N   . ARG   A 1 82  ? 150.818 156.676 164.131 1.00 61.03  ? 108 ARG   A N   1 
ATOM   627  C CA  . ARG   A 1 82  ? 152.144 156.300 164.585 1.00 57.59  ? 108 ARG   A CA  1 
ATOM   628  C C   . ARG   A 1 82  ? 152.099 154.809 164.914 1.00 54.98  ? 108 ARG   A C   1 
ATOM   629  O O   . ARG   A 1 82  ? 151.108 154.348 165.509 1.00 56.39  ? 108 ARG   A O   1 
ATOM   630  C CB  . ARG   A 1 82  ? 152.570 157.106 165.811 1.00 59.21  ? 108 ARG   A CB  1 
ATOM   631  C CG  . ARG   A 1 82  ? 152.600 158.604 165.582 1.00 63.78  ? 108 ARG   A CG  1 
ATOM   632  C CD  . ARG   A 1 82  ? 153.148 159.342 166.794 1.00 71.15  ? 108 ARG   A CD  1 
ATOM   633  N NE  . ARG   A 1 82  ? 152.297 159.190 167.971 1.00 80.87  ? 108 ARG   A NE  1 
ATOM   634  C CZ  . ARG   A 1 82  ? 151.215 159.914 168.231 1.00 82.46  ? 108 ARG   A CZ  1 
ATOM   635  N NH1 . ARG   A 1 82  ? 150.787 160.854 167.402 1.00 79.72  ? 108 ARG   A NH1 1 
ATOM   636  N NH2 . ARG   A 1 82  ? 150.540 159.687 169.355 1.00 76.97  ? 108 ARG   A NH2 1 
ATOM   637  N N   . PRO   A 1 83  ? 153.115 154.020 164.553 1.00 52.70  ? 109 PRO   A N   1 
ATOM   638  C CA  . PRO   A 1 83  ? 153.096 152.606 164.940 1.00 51.05  ? 109 PRO   A CA  1 
ATOM   639  C C   . PRO   A 1 83  ? 153.162 152.425 166.446 1.00 56.92  ? 109 PRO   A C   1 
ATOM   640  O O   . PRO   A 1 83  ? 153.760 153.226 167.169 1.00 60.08  ? 109 PRO   A O   1 
ATOM   641  C CB  . PRO   A 1 83  ? 154.346 152.031 164.267 1.00 50.75  ? 109 PRO   A CB  1 
ATOM   642  C CG  . PRO   A 1 83  ? 154.664 152.951 163.190 1.00 54.30  ? 109 PRO   A CG  1 
ATOM   643  C CD  . PRO   A 1 83  ? 154.249 154.301 163.654 1.00 55.28  ? 109 PRO   A CD  1 
ATOM   644  N N   . LEU   A 1 84  ? 152.536 151.353 166.913 1.00 54.80  ? 110 LEU   A N   1 
ATOM   645  C CA  . LEU   A 1 84  ? 152.635 150.947 168.305 1.00 52.85  ? 110 LEU   A CA  1 
ATOM   646  C C   . LEU   A 1 84  ? 153.920 150.157 168.507 1.00 51.08  ? 110 LEU   A C   1 
ATOM   647  O O   . LEU   A 1 84  ? 154.626 149.843 167.547 1.00 56.19  ? 110 LEU   A O   1 
ATOM   648  C CB  . LEU   A 1 84  ? 151.416 150.111 168.686 1.00 51.14  ? 110 LEU   A CB  1 
ATOM   649  C CG  . LEU   A 1 84  ? 150.041 150.746 168.483 1.00 53.08  ? 110 LEU   A CG  1 
ATOM   650  C CD1 . LEU   A 1 84  ? 148.954 149.747 168.826 1.00 50.93  ? 110 LEU   A CD1 1 
ATOM   651  C CD2 . LEU   A 1 84  ? 149.892 152.003 169.321 1.00 55.84  ? 110 LEU   A CD2 1 
ATOM   652  N N   . PRO   A 1 85  ? 154.269 149.828 169.751 1.00 42.96  ? 111 PRO   A N   1 
ATOM   653  C CA  . PRO   A 1 85  ? 155.399 148.922 169.974 1.00 45.42  ? 111 PRO   A CA  1 
ATOM   654  C C   . PRO   A 1 85  ? 155.175 147.569 169.314 1.00 50.06  ? 111 PRO   A C   1 
ATOM   655  O O   . PRO   A 1 85  ? 154.082 147.230 168.857 1.00 56.27  ? 111 PRO   A O   1 
ATOM   656  C CB  . PRO   A 1 85  ? 155.463 148.810 171.497 1.00 43.44  ? 111 PRO   A CB  1 
ATOM   657  C CG  . PRO   A 1 85  ? 154.933 150.099 171.968 1.00 39.82  ? 111 PRO   A CG  1 
ATOM   658  C CD  . PRO   A 1 85  ? 153.854 150.483 171.003 1.00 40.70  ? 111 PRO   A CD  1 
ATOM   659  N N   . LEU   A 1 86  ? 156.252 146.785 169.268 1.00 45.88  ? 112 LEU   A N   1 
ATOM   660  C CA  . LEU   A 1 86  ? 156.248 145.560 168.477 1.00 47.15  ? 112 LEU   A CA  1 
ATOM   661  C C   . LEU   A 1 86  ? 155.257 144.538 169.023 1.00 51.72  ? 112 LEU   A C   1 
ATOM   662  O O   . LEU   A 1 86  ? 154.562 143.862 168.252 1.00 55.50  ? 112 LEU   A O   1 
ATOM   663  C CB  . LEU   A 1 86  ? 157.660 144.983 168.431 1.00 48.64  ? 112 LEU   A CB  1 
ATOM   664  C CG  . LEU   A 1 86  ? 157.885 143.713 167.614 1.00 52.55  ? 112 LEU   A CG  1 
ATOM   665  C CD1 . LEU   A 1 86  ? 157.471 143.897 166.163 1.00 52.75  ? 112 LEU   A CD1 1 
ATOM   666  C CD2 . LEU   A 1 86  ? 159.340 143.298 167.700 1.00 54.55  ? 112 LEU   A CD2 1 
ATOM   667  N N   . ASP   A 1 87  ? 155.184 144.404 170.348 1.00 47.85  ? 113 ASP   A N   1 
ATOM   668  C CA  . ASP   A 1 87  ? 154.317 143.392 170.942 1.00 46.35  ? 113 ASP   A CA  1 
ATOM   669  C C   . ASP   A 1 87  ? 152.849 143.677 170.655 1.00 44.58  ? 113 ASP   A C   1 
ATOM   670  O O   . ASP   A 1 87  ? 152.075 142.762 170.340 1.00 47.80  ? 113 ASP   A O   1 
ATOM   671  C CB  . ASP   A 1 87  ? 154.566 143.318 172.445 1.00 48.89  ? 113 ASP   A CB  1 
ATOM   672  C CG  . ASP   A 1 87  ? 155.966 142.859 172.774 1.00 53.29  ? 113 ASP   A CG  1 
ATOM   673  O OD1 . ASP   A 1 87  ? 156.428 141.878 172.157 1.00 51.95  ? 113 ASP   A OD1 1 
ATOM   674  O OD2 . ASP   A 1 87  ? 156.610 143.483 173.642 1.00 58.15  ? 113 ASP   A OD2 1 
ATOM   675  N N   . TRP   A 1 88  ? 152.443 144.939 170.761 1.00 38.08  ? 114 TRP   A N   1 
ATOM   676  C CA  . TRP   A 1 88  ? 151.063 145.277 170.450 1.00 39.55  ? 114 TRP   A CA  1 
ATOM   677  C C   . TRP   A 1 88  ? 150.764 145.078 168.969 1.00 42.87  ? 114 TRP   A C   1 
ATOM   678  O O   . TRP   A 1 88  ? 149.637 144.725 168.609 1.00 48.02  ? 114 TRP   A O   1 
ATOM   679  C CB  . TRP   A 1 88  ? 150.774 146.707 170.890 1.00 41.14  ? 114 TRP   A CB  1 
ATOM   680  C CG  . TRP   A 1 88  ? 150.979 146.899 172.360 1.00 40.63  ? 114 TRP   A CG  1 
ATOM   681  C CD1 . TRP   A 1 88  ? 152.112 147.319 172.979 1.00 42.74  ? 114 TRP   A CD1 1 
ATOM   682  C CD2 . TRP   A 1 88  ? 150.022 146.663 173.396 1.00 41.51  ? 114 TRP   A CD2 1 
ATOM   683  N NE1 . TRP   A 1 88  ? 151.925 147.366 174.335 1.00 38.85  ? 114 TRP   A NE1 1 
ATOM   684  C CE2 . TRP   A 1 88  ? 150.647 146.966 174.617 1.00 39.19  ? 114 TRP   A CE2 1 
ATOM   685  C CE3 . TRP   A 1 88  ? 148.695 146.226 173.408 1.00 46.07  ? 114 TRP   A CE3 1 
ATOM   686  C CZ2 . TRP   A 1 88  ? 149.993 146.850 175.838 1.00 42.89  ? 114 TRP   A CZ2 1 
ATOM   687  C CZ3 . TRP   A 1 88  ? 148.047 146.110 174.621 1.00 47.21  ? 114 TRP   A CZ3 1 
ATOM   688  C CH2 . TRP   A 1 88  ? 148.696 146.421 175.819 1.00 45.79  ? 114 TRP   A CH2 1 
ATOM   689  N N   . MET   A 1 89  ? 151.758 145.267 168.101 1.00 41.83  ? 115 MET   A N   1 
ATOM   690  C CA  . MET   A 1 89  ? 151.569 144.949 166.689 1.00 42.61  ? 115 MET   A CA  1 
ATOM   691  C C   . MET   A 1 89  ? 151.350 143.453 166.490 1.00 44.01  ? 115 MET   A C   1 
ATOM   692  O O   . MET   A 1 89  ? 150.508 143.039 165.679 1.00 46.48  ? 115 MET   A O   1 
ATOM   693  C CB  . MET   A 1 89  ? 152.768 145.436 165.880 1.00 41.58  ? 115 MET   A CB  1 
ATOM   694  C CG  . MET   A 1 89  ? 152.817 146.937 165.681 1.00 45.22  ? 115 MET   A CG  1 
ATOM   695  S SD  . MET   A 1 89  ? 151.635 147.505 164.452 1.00 58.17  ? 115 MET   A SD  1 
ATOM   696  C CE  . MET   A 1 89  ? 152.094 149.227 164.322 1.00 54.02  ? 115 MET   A CE  1 
ATOM   697  N N   . TYR   A 1 90  ? 152.096 142.624 167.224 1.00 41.24  ? 116 TYR   A N   1 
ATOM   698  C CA  . TYR   A 1 90  ? 151.856 141.184 167.175 1.00 39.83  ? 116 TYR   A CA  1 
ATOM   699  C C   . TYR   A 1 90  ? 150.444 140.847 167.639 1.00 38.98  ? 116 TYR   A C   1 
ATOM   700  O O   . TYR   A 1 90  ? 149.781 139.977 167.061 1.00 42.70  ? 116 TYR   A O   1 
ATOM   701  C CB  . TYR   A 1 90  ? 152.886 140.446 168.029 1.00 41.92  ? 116 TYR   A CB  1 
ATOM   702  C CG  . TYR   A 1 90  ? 154.180 140.127 167.314 1.00 42.53  ? 116 TYR   A CG  1 
ATOM   703  C CD1 . TYR   A 1 90  ? 154.221 139.179 166.304 1.00 48.69  ? 116 TYR   A CD1 1 
ATOM   704  C CD2 . TYR   A 1 90  ? 155.360 140.759 167.660 1.00 41.73  ? 116 TYR   A CD2 1 
ATOM   705  C CE1 . TYR   A 1 90  ? 155.397 138.882 165.654 1.00 48.93  ? 116 TYR   A CE1 1 
ATOM   706  C CE2 . TYR   A 1 90  ? 156.537 140.464 167.017 1.00 43.78  ? 116 TYR   A CE2 1 
ATOM   707  C CZ  . TYR   A 1 90  ? 156.551 139.527 166.016 1.00 47.23  ? 116 TYR   A CZ  1 
ATOM   708  O OH  . TYR   A 1 90  ? 157.728 139.232 165.370 1.00 52.85  ? 116 TYR   A OH  1 
ATOM   709  N N   . LEU   A 1 91  ? 149.970 141.522 168.685 1.00 36.93  ? 117 LEU   A N   1 
ATOM   710  C CA  . LEU   A 1 91  ? 148.599 141.304 169.144 1.00 32.79  ? 117 LEU   A CA  1 
ATOM   711  C C   . LEU   A 1 91  ? 147.589 141.694 168.070 1.00 35.09  ? 117 LEU   A C   1 
ATOM   712  O O   . LEU   A 1 91  ? 146.574 141.010 167.878 1.00 39.52  ? 117 LEU   A O   1 
ATOM   713  C CB  . LEU   A 1 91  ? 148.349 142.092 170.429 1.00 35.75  ? 117 LEU   A CB  1 
ATOM   714  C CG  . LEU   A 1 91  ? 146.967 141.987 171.068 1.00 37.18  ? 117 LEU   A CG  1 
ATOM   715  C CD1 . LEU   A 1 91  ? 146.628 140.552 171.420 1.00 41.02  ? 117 LEU   A CD1 1 
ATOM   716  C CD2 . LEU   A 1 91  ? 146.904 142.862 172.301 1.00 41.14  ? 117 LEU   A CD2 1 
ATOM   717  N N   . VAL   A 1 92  ? 147.846 142.800 167.372 1.00 36.17  ? 118 VAL   A N   1 
ATOM   718  C CA  . VAL   A 1 92  ? 146.965 143.234 166.291 1.00 34.23  ? 118 VAL   A CA  1 
ATOM   719  C C   . VAL   A 1 92  ? 146.901 142.173 165.199 1.00 36.48  ? 118 VAL   A C   1 
ATOM   720  O O   . VAL   A 1 92  ? 145.821 141.851 164.681 1.00 40.26  ? 118 VAL   A O   1 
ATOM   721  C CB  . VAL   A 1 92  ? 147.439 144.594 165.744 1.00 34.46  ? 118 VAL   A CB  1 
ATOM   722  C CG1 . VAL   A 1 92  ? 146.760 144.923 164.452 1.00 36.79  ? 118 VAL   A CG1 1 
ATOM   723  C CG2 . VAL   A 1 92  ? 147.153 145.691 166.746 1.00 37.23  ? 118 VAL   A CG2 1 
ATOM   724  N N   . TYR   A 1 93  ? 148.051 141.617 164.826 1.00 36.69  ? 119 TYR   A N   1 
ATOM   725  C CA  . TYR   A 1 93  ? 148.052 140.571 163.807 1.00 38.12  ? 119 TYR   A CA  1 
ATOM   726  C C   . TYR   A 1 93  ? 147.360 139.302 164.298 1.00 38.28  ? 119 TYR   A C   1 
ATOM   727  O O   . TYR   A 1 93  ? 146.731 138.593 163.502 1.00 41.00  ? 119 TYR   A O   1 
ATOM   728  C CB  . TYR   A 1 93  ? 149.480 140.269 163.363 1.00 40.44  ? 119 TYR   A CB  1 
ATOM   729  C CG  . TYR   A 1 93  ? 150.022 141.262 162.363 1.00 40.04  ? 119 TYR   A CG  1 
ATOM   730  C CD1 . TYR   A 1 93  ? 149.627 141.224 161.039 1.00 39.90  ? 119 TYR   A CD1 1 
ATOM   731  C CD2 . TYR   A 1 93  ? 150.931 142.232 162.742 1.00 39.90  ? 119 TYR   A CD2 1 
ATOM   732  C CE1 . TYR   A 1 93  ? 150.118 142.121 160.125 1.00 41.09  ? 119 TYR   A CE1 1 
ATOM   733  C CE2 . TYR   A 1 93  ? 151.427 143.133 161.833 1.00 40.36  ? 119 TYR   A CE2 1 
ATOM   734  C CZ  . TYR   A 1 93  ? 151.016 143.073 160.525 1.00 42.80  ? 119 TYR   A CZ  1 
ATOM   735  O OH  . TYR   A 1 93  ? 151.509 143.973 159.611 1.00 51.00  ? 119 TYR   A OH  1 
ATOM   736  N N   . THR   A 1 94  ? 147.459 138.995 165.592 1.00 35.01  ? 120 THR   A N   1 
ATOM   737  C CA  . THR   A 1 94  ? 146.709 137.865 166.135 1.00 31.11  ? 120 THR   A CA  1 
ATOM   738  C C   . THR   A 1 94  ? 145.210 138.096 166.008 1.00 37.78  ? 120 THR   A C   1 
ATOM   739  O O   . THR   A 1 94  ? 144.454 137.172 165.682 1.00 42.58  ? 120 THR   A O   1 
ATOM   740  C CB  . THR   A 1 94  ? 147.083 137.633 167.598 1.00 36.90  ? 120 THR   A CB  1 
ATOM   741  O OG1 . THR   A 1 94  ? 148.486 137.360 167.698 1.00 45.52  ? 120 THR   A OG1 1 
ATOM   742  C CG2 . THR   A 1 94  ? 146.303 136.466 168.172 1.00 37.18  ? 120 THR   A CG2 1 
ATOM   743  N N   . ILE   A 1 95  ? 144.763 139.326 166.266 1.00 36.43  ? 121 ILE   A N   1 
ATOM   744  C CA  . ILE   A 1 95  ? 143.349 139.652 166.094 1.00 31.80  ? 121 ILE   A CA  1 
ATOM   745  C C   . ILE   A 1 95  ? 142.940 139.490 164.633 1.00 34.17  ? 121 ILE   A C   1 
ATOM   746  O O   . ILE   A 1 95  ? 141.851 138.982 164.331 1.00 37.54  ? 121 ILE   A O   1 
ATOM   747  C CB  . ILE   A 1 95  ? 143.062 141.071 166.620 1.00 28.38  ? 121 ILE   A CB  1 
ATOM   748  C CG1 . ILE   A 1 95  ? 143.162 141.090 168.147 1.00 27.27  ? 121 ILE   A CG1 1 
ATOM   749  C CG2 . ILE   A 1 95  ? 141.688 141.550 166.168 1.00 33.96  ? 121 ILE   A CG2 1 
ATOM   750  C CD1 . ILE   A 1 95  ? 143.281 142.470 168.752 1.00 32.83  ? 121 ILE   A CD1 1 
ATOM   751  N N   . MET   A 1 96  ? 143.800 139.924 163.707 1.00 33.97  ? 122 MET   A N   1 
ATOM   752  C CA  . MET   A 1 96  ? 143.534 139.706 162.285 1.00 35.80  ? 122 MET   A CA  1 
ATOM   753  C C   . MET   A 1 96  ? 143.357 138.227 161.976 1.00 38.78  ? 122 MET   A C   1 
ATOM   754  O O   . MET   A 1 96  ? 142.427 137.839 161.258 1.00 40.56  ? 122 MET   A O   1 
ATOM   755  C CB  . MET   A 1 96  ? 144.675 140.253 161.430 1.00 38.92  ? 122 MET   A CB  1 
ATOM   756  C CG  . MET   A 1 96  ? 144.674 141.736 161.243 1.00 43.29  ? 122 MET   A CG  1 
ATOM   757  S SD  . MET   A 1 96  ? 146.084 142.345 160.298 1.00 53.19  ? 122 MET   A SD  1 
ATOM   758  C CE  . MET   A 1 96  ? 145.785 141.603 158.703 1.00 39.81  ? 122 MET   A CE  1 
ATOM   759  N N   . PHE   A 1 97  ? 144.262 137.393 162.485 1.00 37.86  ? 123 PHE   A N   1 
ATOM   760  C CA  . PHE   A 1 97  ? 144.203 135.964 162.204 1.00 35.79  ? 123 PHE   A CA  1 
ATOM   761  C C   . PHE   A 1 97  ? 142.924 135.349 162.759 1.00 39.09  ? 123 PHE   A C   1 
ATOM   762  O O   . PHE   A 1 97  ? 142.286 134.514 162.100 1.00 44.37  ? 123 PHE   A O   1 
ATOM   763  C CB  . PHE   A 1 97  ? 145.432 135.281 162.797 1.00 37.47  ? 123 PHE   A CB  1 
ATOM   764  C CG  . PHE   A 1 97  ? 145.625 133.868 162.345 1.00 39.73  ? 123 PHE   A CG  1 
ATOM   765  C CD1 . PHE   A 1 97  ? 146.357 133.588 161.209 1.00 40.73  ? 123 PHE   A CD1 1 
ATOM   766  C CD2 . PHE   A 1 97  ? 145.094 132.817 163.067 1.00 43.60  ? 123 PHE   A CD2 1 
ATOM   767  C CE1 . PHE   A 1 97  ? 146.546 132.291 160.795 1.00 44.46  ? 123 PHE   A CE1 1 
ATOM   768  C CE2 . PHE   A 1 97  ? 145.277 131.518 162.657 1.00 46.16  ? 123 PHE   A CE2 1 
ATOM   769  C CZ  . PHE   A 1 97  ? 146.005 131.253 161.519 1.00 45.98  ? 123 PHE   A CZ  1 
ATOM   770  N N   . LEU   A 1 98  ? 142.534 135.749 163.972 1.00 36.60  ? 124 LEU   A N   1 
ATOM   771  C CA  . LEU   A 1 98  ? 141.296 135.235 164.553 1.00 34.63  ? 124 LEU   A CA  1 
ATOM   772  C C   . LEU   A 1 98  ? 140.091 135.640 163.717 1.00 34.34  ? 124 LEU   A C   1 
ATOM   773  O O   . LEU   A 1 98  ? 139.197 134.822 163.466 1.00 37.54  ? 124 LEU   A O   1 
ATOM   774  C CB  . LEU   A 1 98  ? 141.137 135.727 165.990 1.00 33.94  ? 124 LEU   A CB  1 
ATOM   775  C CG  . LEU   A 1 98  ? 141.582 134.762 167.090 1.00 37.53  ? 124 LEU   A CG  1 
ATOM   776  C CD1 . LEU   A 1 98  ? 143.003 134.285 166.874 1.00 37.38  ? 124 LEU   A CD1 1 
ATOM   777  C CD2 . LEU   A 1 98  ? 141.444 135.428 168.444 1.00 36.17  ? 124 LEU   A CD2 1 
ATOM   778  N N   . GLY   A 1 99  ? 140.055 136.894 163.266 1.00 36.25  ? 125 GLY   A N   1 
ATOM   779  C CA  . GLY   A 1 99  ? 138.959 137.328 162.416 1.00 37.30  ? 125 GLY   A CA  1 
ATOM   780  C C   . GLY   A 1 99  ? 138.903 136.572 161.103 1.00 36.87  ? 125 GLY   A C   1 
ATOM   781  O O   . GLY   A 1 99  ? 137.823 136.220 160.622 1.00 40.84  ? 125 GLY   A O   1 
ATOM   782  N N   . ALA   A 1 100 ? 140.065 136.321 160.501 1.00 34.44  ? 126 ALA   A N   1 
ATOM   783  C CA  . ALA   A 1 100 ? 140.097 135.592 159.239 1.00 35.31  ? 126 ALA   A CA  1 
ATOM   784  C C   . ALA   A 1 100 ? 139.607 134.160 159.413 1.00 35.25  ? 126 ALA   A C   1 
ATOM   785  O O   . ALA   A 1 100 ? 138.845 133.651 158.580 1.00 41.48  ? 126 ALA   A O   1 
ATOM   786  C CB  . ALA   A 1 100 ? 141.509 135.613 158.661 1.00 39.96  ? 126 ALA   A CB  1 
ATOM   787  N N   . LEU   A 1 101 ? 140.027 133.491 160.490 1.00 35.42  ? 127 LEU   A N   1 
ATOM   788  C CA  . LEU   A 1 101 ? 139.521 132.146 160.751 1.00 36.24  ? 127 LEU   A CA  1 
ATOM   789  C C   . LEU   A 1 101 ? 138.017 132.162 160.987 1.00 37.15  ? 127 LEU   A C   1 
ATOM   790  O O   . LEU   A 1 101 ? 137.297 131.271 160.516 1.00 40.72  ? 127 LEU   A O   1 
ATOM   791  C CB  . LEU   A 1 101 ? 140.230 131.524 161.956 1.00 38.16  ? 127 LEU   A CB  1 
ATOM   792  C CG  . LEU   A 1 101 ? 141.587 130.849 161.769 1.00 40.66  ? 127 LEU   A CG  1 
ATOM   793  C CD1 . LEU   A 1 101 ? 142.080 130.340 163.108 1.00 40.68  ? 127 LEU   A CD1 1 
ATOM   794  C CD2 . LEU   A 1 101 ? 141.521 129.709 160.766 1.00 42.61  ? 127 LEU   A CD2 1 
ATOM   795  N N   . GLY   A 1 102 ? 137.523 133.160 161.721 1.00 37.42  ? 128 GLY   A N   1 
ATOM   796  C CA  . GLY   A 1 102 ? 136.090 133.267 161.933 1.00 35.05  ? 128 GLY   A CA  1 
ATOM   797  C C   . GLY   A 1 102 ? 135.325 133.448 160.637 1.00 35.83  ? 128 GLY   A C   1 
ATOM   798  O O   . GLY   A 1 102 ? 134.255 132.866 160.450 1.00 41.43  ? 128 GLY   A O   1 
ATOM   799  N N   . MET   A 1 103 ? 135.860 134.262 159.727 1.00 37.40  ? 129 MET   A N   1 
ATOM   800  C CA  . MET   A 1 103 ? 135.241 134.407 158.414 1.00 39.78  ? 129 MET   A CA  1 
ATOM   801  C C   . MET   A 1 103 ? 135.252 133.091 157.651 1.00 39.14  ? 129 MET   A C   1 
ATOM   802  O O   . MET   A 1 103 ? 134.273 132.749 156.979 1.00 42.09  ? 129 MET   A O   1 
ATOM   803  C CB  . MET   A 1 103 ? 135.956 135.489 157.606 1.00 45.72  ? 129 MET   A CB  1 
ATOM   804  C CG  . MET   A 1 103 ? 135.457 136.895 157.874 1.00 48.29  ? 129 MET   A CG  1 
ATOM   805  S SD  . MET   A 1 103 ? 136.451 138.163 157.070 1.00 61.51  ? 129 MET   A SD  1 
ATOM   806  C CE  . MET   A 1 103 ? 136.229 137.747 155.347 1.00 46.28  ? 129 MET   A CE  1 
ATOM   807  N N   . MET   A 1 104 ? 136.356 132.347 157.728 1.00 38.54  ? 130 MET   A N   1 
ATOM   808  C CA  . MET   A 1 104 ? 136.442 131.078 157.011 1.00 37.58  ? 130 MET   A CA  1 
ATOM   809  C C   . MET   A 1 104 ? 135.400 130.088 157.516 1.00 40.56  ? 130 MET   A C   1 
ATOM   810  O O   . MET   A 1 104 ? 134.669 129.483 156.725 1.00 43.89  ? 130 MET   A O   1 
ATOM   811  C CB  . MET   A 1 104 ? 137.848 130.491 157.155 1.00 41.61  ? 130 MET   A CB  1 
ATOM   812  C CG  . MET   A 1 104 ? 138.113 129.277 156.277 1.00 43.97  ? 130 MET   A CG  1 
ATOM   813  S SD  . MET   A 1 104 ? 139.740 128.548 156.536 1.00 58.12  ? 130 MET   A SD  1 
ATOM   814  C CE  . MET   A 1 104 ? 139.538 127.838 158.164 1.00 46.84  ? 130 MET   A CE  1 
ATOM   815  N N   . LEU   A 1 105 ? 135.312 129.913 158.831 1.00 38.28  ? 131 LEU   A N   1 
ATOM   816  C CA  . LEU   A 1 105 ? 134.427 128.914 159.418 1.00 36.71  ? 131 LEU   A CA  1 
ATOM   817  C C   . LEU   A 1 105 ? 133.024 129.436 159.698 1.00 36.59  ? 131 LEU   A C   1 
ATOM   818  O O   . LEU   A 1 105 ? 132.162 128.652 160.104 1.00 42.53  ? 131 LEU   A O   1 
ATOM   819  C CB  . LEU   A 1 105 ? 135.032 128.378 160.719 1.00 35.62  ? 131 LEU   A CB  1 
ATOM   820  C CG  . LEU   A 1 105 ? 136.383 127.676 160.609 1.00 35.93  ? 131 LEU   A CG  1 
ATOM   821  C CD1 . LEU   A 1 105 ? 136.951 127.429 161.990 1.00 36.69  ? 131 LEU   A CD1 1 
ATOM   822  C CD2 . LEU   A 1 105 ? 136.261 126.374 159.845 1.00 38.77  ? 131 LEU   A CD2 1 
ATOM   823  N N   . GLY   A 1 106 ? 132.768 130.723 159.496 1.00 35.46  ? 132 GLY   A N   1 
ATOM   824  C CA  . GLY   A 1 106 ? 131.444 131.264 159.744 1.00 35.32  ? 132 GLY   A CA  1 
ATOM   825  C C   . GLY   A 1 106 ? 131.046 131.247 161.202 1.00 36.75  ? 132 GLY   A C   1 
ATOM   826  O O   . GLY   A 1 106 ? 129.882 130.969 161.518 1.00 42.32  ? 132 GLY   A O   1 
ATOM   827  N N   . LEU   A 1 107 ? 131.985 131.541 162.097 1.00 35.86  ? 133 LEU   A N   1 
ATOM   828  C CA  . LEU   A 1 107 ? 131.769 131.514 163.540 1.00 37.16  ? 133 LEU   A CA  1 
ATOM   829  C C   . LEU   A 1 107 ? 131.829 132.945 164.056 1.00 36.97  ? 133 LEU   A C   1 
ATOM   830  O O   . LEU   A 1 107 ? 132.890 133.578 164.019 1.00 37.78  ? 133 LEU   A O   1 
ATOM   831  C CB  . LEU   A 1 107 ? 132.815 130.628 164.212 1.00 36.80  ? 133 LEU   A CB  1 
ATOM   832  C CG  . LEU   A 1 107 ? 132.750 130.420 165.722 1.00 36.01  ? 133 LEU   A CG  1 
ATOM   833  C CD1 . LEU   A 1 107 ? 131.409 129.865 166.151 1.00 38.88  ? 133 LEU   A CD1 1 
ATOM   834  C CD2 . LEU   A 1 107 ? 133.869 129.493 166.146 1.00 34.54  ? 133 LEU   A CD2 1 
ATOM   835  N N   . CYS   A 1 108 ? 130.693 133.450 164.538 1.00 34.59  ? 134 CYS   A N   1 
ATOM   836  C CA  . CYS   A 1 108 ? 130.561 134.839 164.974 1.00 34.78  ? 134 CYS   A CA  1 
ATOM   837  C C   . CYS   A 1 108 ? 130.939 135.784 163.833 1.00 36.76  ? 134 CYS   A C   1 
ATOM   838  O O   . CYS   A 1 108 ? 131.910 136.541 163.905 1.00 43.33  ? 134 CYS   A O   1 
ATOM   839  C CB  . CYS   A 1 108 ? 131.398 135.105 166.228 1.00 39.67  ? 134 CYS   A CB  1 
ATOM   840  S SG  . CYS   A 1 108 ? 130.900 134.128 167.658 1.00 58.25  ? 134 CYS   A SG  1 
ATOM   841  N N   . TYR   A 1 109 ? 130.144 135.714 162.764 1.00 32.81  ? 135 TYR   A N   1 
ATOM   842  C CA  . TYR   A 1 109 ? 130.585 136.213 161.466 1.00 34.49  ? 135 TYR   A CA  1 
ATOM   843  C C   . TYR   A 1 109 ? 130.807 137.721 161.474 1.00 39.67  ? 135 TYR   A C   1 
ATOM   844  O O   . TYR   A 1 109 ? 131.831 138.205 160.980 1.00 45.45  ? 135 TYR   A O   1 
ATOM   845  C CB  . TYR   A 1 109 ? 129.571 135.826 160.396 1.00 35.89  ? 135 TYR   A CB  1 
ATOM   846  C CG  . TYR   A 1 109 ? 129.920 136.341 159.030 1.00 35.00  ? 135 TYR   A CG  1 
ATOM   847  C CD1 . TYR   A 1 109 ? 131.010 135.850 158.345 1.00 35.93  ? 135 TYR   A CD1 1 
ATOM   848  C CD2 . TYR   A 1 109 ? 129.152 137.319 158.425 1.00 40.15  ? 135 TYR   A CD2 1 
ATOM   849  C CE1 . TYR   A 1 109 ? 131.330 136.320 157.100 1.00 41.86  ? 135 TYR   A CE1 1 
ATOM   850  C CE2 . TYR   A 1 109 ? 129.465 137.794 157.181 1.00 41.33  ? 135 TYR   A CE2 1 
ATOM   851  C CZ  . TYR   A 1 109 ? 130.553 137.291 156.522 1.00 43.32  ? 135 TYR   A CZ  1 
ATOM   852  O OH  . TYR   A 1 109 ? 130.865 137.763 155.272 1.00 49.75  ? 135 TYR   A OH  1 
ATOM   853  N N   . ARG   A 1 110 ? 129.860 138.486 162.017 1.00 36.48  ? 136 ARG   A N   1 
ATOM   854  C CA  . ARG   A 1 110 ? 130.011 139.940 162.007 1.00 36.36  ? 136 ARG   A CA  1 
ATOM   855  C C   . ARG   A 1 110 ? 131.173 140.385 162.888 1.00 41.07  ? 136 ARG   A C   1 
ATOM   856  O O   . ARG   A 1 110 ? 131.951 141.270 162.503 1.00 45.43  ? 136 ARG   A O   1 
ATOM   857  C CB  . ARG   A 1 110 ? 128.708 140.611 162.444 1.00 34.58  ? 136 ARG   A CB  1 
ATOM   858  C CG  . ARG   A 1 110 ? 127.806 141.047 161.294 1.00 38.59  ? 136 ARG   A CG  1 
ATOM   859  C CD  . ARG   A 1 110 ? 127.538 139.931 160.297 1.00 42.14  ? 136 ARG   A CD  1 
ATOM   860  N NE  . ARG   A 1 110 ? 126.553 140.318 159.292 1.00 42.92  ? 136 ARG   A NE  1 
ATOM   861  C CZ  . ARG   A 1 110 ? 125.242 140.137 159.386 1.00 52.76  ? 136 ARG   A CZ  1 
ATOM   862  N NH1 . ARG   A 1 110 ? 124.686 139.576 160.450 1.00 54.08  ? 136 ARG   A NH1 1 
ATOM   863  N NH2 . ARG   A 1 110 ? 124.462 140.531 158.383 1.00 54.60  ? 136 ARG   A NH2 1 
ATOM   864  N N   . ILE   A 1 111 ? 131.309 139.779 164.068 1.00 36.27  ? 137 ILE   A N   1 
ATOM   865  C CA  . ILE   A 1 111 ? 132.415 140.121 164.956 1.00 32.82  ? 137 ILE   A CA  1 
ATOM   866  C C   . ILE   A 1 111 ? 133.744 139.777 164.299 1.00 35.23  ? 137 ILE   A C   1 
ATOM   867  O O   . ILE   A 1 111 ? 134.700 140.562 164.348 1.00 39.22  ? 137 ILE   A O   1 
ATOM   868  C CB  . ILE   A 1 111 ? 132.252 139.407 166.310 1.00 33.21  ? 137 ILE   A CB  1 
ATOM   869  C CG1 . ILE   A 1 111 ? 130.996 139.903 167.037 1.00 34.57  ? 137 ILE   A CG1 1 
ATOM   870  C CG2 . ILE   A 1 111 ? 133.494 139.624 167.170 1.00 37.71  ? 137 ILE   A CG2 1 
ATOM   871  C CD1 . ILE   A 1 111 ? 130.543 139.007 168.171 1.00 37.56  ? 137 ILE   A CD1 1 
ATOM   872  N N   . SER   A 1 112 ? 133.825 138.605 163.668 1.00 32.67  ? 138 SER   A N   1 
ATOM   873  C CA  . SER   A 1 112 ? 135.055 138.211 162.989 1.00 35.55  ? 138 SER   A CA  1 
ATOM   874  C C   . SER   A 1 112 ? 135.380 139.160 161.844 1.00 40.45  ? 138 SER   A C   1 
ATOM   875  O O   . SER   A 1 112 ? 136.545 139.525 161.637 1.00 45.75  ? 138 SER   A O   1 
ATOM   876  C CB  . SER   A 1 112 ? 134.930 136.780 162.475 1.00 36.49  ? 138 SER   A CB  1 
ATOM   877  O OG  . SER   A 1 112 ? 134.578 135.895 163.521 1.00 39.82  ? 138 SER   A OG  1 
ATOM   878  N N   . CYS   A 1 113 ? 134.361 139.569 161.087 1.00 36.86  ? 139 CYS   A N   1 
ATOM   879  C CA  . CYS   A 1 113 ? 134.582 140.495 159.984 1.00 38.78  ? 139 CYS   A CA  1 
ATOM   880  C C   . CYS   A 1 113 ? 135.111 141.833 160.481 1.00 41.75  ? 139 CYS   A C   1 
ATOM   881  O O   . CYS   A 1 113 ? 136.021 142.405 159.876 1.00 47.67  ? 139 CYS   A O   1 
ATOM   882  C CB  . CYS   A 1 113 ? 133.289 140.687 159.196 1.00 42.45  ? 139 CYS   A CB  1 
ATOM   883  S SG  . CYS   A 1 113 ? 132.904 139.329 158.077 1.00 61.13  ? 139 CYS   A SG  1 
ATOM   884  N N   . VAL   A 1 114 ? 134.554 142.353 161.576 1.00 36.64  ? 140 VAL   A N   1 
ATOM   885  C CA  . VAL   A 1 114 ? 135.049 143.618 162.119 1.00 34.12  ? 140 VAL   A CA  1 
ATOM   886  C C   . VAL   A 1 114 ? 136.483 143.463 162.617 1.00 35.45  ? 140 VAL   A C   1 
ATOM   887  O O   . VAL   A 1 114 ? 137.343 144.332 162.381 1.00 41.31  ? 140 VAL   A O   1 
ATOM   888  C CB  . VAL   A 1 114 ? 134.111 144.123 163.231 1.00 34.84  ? 140 VAL   A CB  1 
ATOM   889  C CG1 . VAL   A 1 114 ? 134.719 145.310 163.956 1.00 36.28  ? 140 VAL   A CG1 1 
ATOM   890  C CG2 . VAL   A 1 114 ? 132.759 144.502 162.651 1.00 37.02  ? 140 VAL   A CG2 1 
ATOM   891  N N   . LEU   A 1 115 ? 136.764 142.356 163.316 1.00 32.23  ? 141 LEU   A N   1 
ATOM   892  C CA  . LEU   A 1 115 ? 138.104 142.117 163.844 1.00 35.20  ? 141 LEU   A CA  1 
ATOM   893  C C   . LEU   A 1 115 ? 139.134 141.981 162.734 1.00 39.83  ? 141 LEU   A C   1 
ATOM   894  O O   . LEU   A 1 115 ? 140.310 142.298 162.941 1.00 44.86  ? 141 LEU   A O   1 
ATOM   895  C CB  . LEU   A 1 115 ? 138.113 140.861 164.716 1.00 33.76  ? 141 LEU   A CB  1 
ATOM   896  C CG  . LEU   A 1 115 ? 137.394 140.912 166.066 1.00 36.19  ? 141 LEU   A CG  1 
ATOM   897  C CD1 . LEU   A 1 115 ? 137.368 139.532 166.679 1.00 33.96  ? 141 LEU   A CD1 1 
ATOM   898  C CD2 . LEU   A 1 115 ? 138.053 141.897 167.012 1.00 37.39  ? 141 LEU   A CD2 1 
ATOM   899  N N   . PHE   A 1 116 ? 138.732 141.473 161.571 1.00 35.93  ? 142 PHE   A N   1 
ATOM   900  C CA  . PHE   A 1 116 ? 139.637 141.457 160.428 1.00 33.92  ? 142 PHE   A CA  1 
ATOM   901  C C   . PHE   A 1 116 ? 139.744 142.828 159.773 1.00 37.78  ? 142 PHE   A C   1 
ATOM   902  O O   . PHE   A 1 116 ? 140.831 143.233 159.349 1.00 42.47  ? 142 PHE   A O   1 
ATOM   903  C CB  . PHE   A 1 116 ? 139.170 140.429 159.402 1.00 37.38  ? 142 PHE   A CB  1 
ATOM   904  C CG  . PHE   A 1 116 ? 140.083 140.299 158.218 1.00 41.21  ? 142 PHE   A CG  1 
ATOM   905  C CD1 . PHE   A 1 116 ? 141.199 139.488 158.277 1.00 47.13  ? 142 PHE   A CD1 1 
ATOM   906  C CD2 . PHE   A 1 116 ? 139.823 140.978 157.045 1.00 40.22  ? 142 PHE   A CD2 1 
ATOM   907  C CE1 . PHE   A 1 116 ? 142.036 139.363 157.191 1.00 48.78  ? 142 PHE   A CE1 1 
ATOM   908  C CE2 . PHE   A 1 116 ? 140.659 140.857 155.960 1.00 41.81  ? 142 PHE   A CE2 1 
ATOM   909  C CZ  . PHE   A 1 116 ? 141.764 140.048 156.032 1.00 46.33  ? 142 PHE   A CZ  1 
ATOM   910  N N   . LEU   A 1 117 ? 138.628 143.549 159.679 1.00 39.93  ? 143 LEU   A N   1 
ATOM   911  C CA  . LEU   A 1 117 ? 138.581 144.756 158.864 1.00 39.40  ? 143 LEU   A CA  1 
ATOM   912  C C   . LEU   A 1 117 ? 139.381 145.888 159.489 1.00 40.55  ? 143 LEU   A C   1 
ATOM   913  O O   . LEU   A 1 117 ? 140.203 146.521 158.817 1.00 44.42  ? 143 LEU   A O   1 
ATOM   914  C CB  . LEU   A 1 117 ? 137.126 145.180 158.667 1.00 38.40  ? 143 LEU   A CB  1 
ATOM   915  C CG  . LEU   A 1 117 ? 136.829 146.398 157.796 1.00 40.38  ? 143 LEU   A CG  1 
ATOM   916  C CD1 . LEU   A 1 117 ? 137.128 146.098 156.342 1.00 44.06  ? 143 LEU   A CD1 1 
ATOM   917  C CD2 . LEU   A 1 117 ? 135.387 146.821 157.979 1.00 39.31  ? 143 LEU   A CD2 1 
ATOM   918  N N   . LEU   A 1 118 ? 139.152 146.167 160.776 1.00 37.70  ? 144 LEU   A N   1 
ATOM   919  C CA  . LEU   A 1 118 ? 139.755 147.369 161.355 1.00 37.73  ? 144 LEU   A CA  1 
ATOM   920  C C   . LEU   A 1 118 ? 141.277 147.270 161.427 1.00 43.92  ? 144 LEU   A C   1 
ATOM   921  O O   . LEU   A 1 118 ? 141.962 148.203 160.961 1.00 46.76  ? 144 LEU   A O   1 
ATOM   922  C CB  . LEU   A 1 118 ? 139.123 147.661 162.720 1.00 33.89  ? 144 LEU   A CB  1 
ATOM   923  C CG  . LEU   A 1 118 ? 137.848 148.505 162.704 1.00 36.94  ? 144 LEU   A CG  1 
ATOM   924  C CD1 . LEU   A 1 118 ? 136.790 147.884 161.817 1.00 39.77  ? 144 LEU   A CD1 1 
ATOM   925  C CD2 . LEU   A 1 118 ? 137.320 148.683 164.112 1.00 39.17  ? 144 LEU   A CD2 1 
ATOM   926  N N   . PRO   A 1 119 ? 141.868 146.203 161.976 1.00 40.59  ? 145 PRO   A N   1 
ATOM   927  C CA  . PRO   A 1 119 ? 143.326 146.039 161.887 1.00 37.27  ? 145 PRO   A CA  1 
ATOM   928  C C   . PRO   A 1 119 ? 143.901 146.084 160.482 1.00 41.43  ? 145 PRO   A C   1 
ATOM   929  O O   . PRO   A 1 119 ? 144.981 146.660 160.281 1.00 48.92  ? 145 PRO   A O   1 
ATOM   930  C CB  . PRO   A 1 119 ? 143.518 144.657 162.502 1.00 34.23  ? 145 PRO   A CB  1 
ATOM   931  C CG  . PRO   A 1 119 ? 142.513 144.594 163.549 1.00 35.23  ? 145 PRO   A CG  1 
ATOM   932  C CD  . PRO   A 1 119 ? 141.304 145.301 162.994 1.00 39.24  ? 145 PRO   A CD  1 
ATOM   933  N N   . TYR   A 1 120 ? 143.231 145.463 159.508 1.00 38.36  ? 146 TYR   A N   1 
ATOM   934  C CA  . TYR   A 1 120 ? 143.765 145.437 158.151 1.00 40.46  ? 146 TYR   A CA  1 
ATOM   935  C C   . TYR   A 1 120 ? 143.902 146.846 157.599 1.00 42.58  ? 146 TYR   A C   1 
ATOM   936  O O   . TYR   A 1 120 ? 144.929 147.199 157.010 1.00 45.85  ? 146 TYR   A O   1 
ATOM   937  C CB  . TYR   A 1 120 ? 142.869 144.594 157.244 1.00 41.34  ? 146 TYR   A CB  1 
ATOM   938  C CG  . TYR   A 1 120 ? 143.402 144.421 155.836 1.00 40.13  ? 146 TYR   A CG  1 
ATOM   939  C CD1 . TYR   A 1 120 ? 143.103 145.338 154.838 1.00 43.20  ? 146 TYR   A CD1 1 
ATOM   940  C CD2 . TYR   A 1 120 ? 144.195 143.336 155.504 1.00 41.55  ? 146 TYR   A CD2 1 
ATOM   941  C CE1 . TYR   A 1 120 ? 143.587 145.186 153.562 1.00 42.34  ? 146 TYR   A CE1 1 
ATOM   942  C CE2 . TYR   A 1 120 ? 144.678 143.174 154.225 1.00 44.33  ? 146 TYR   A CE2 1 
ATOM   943  C CZ  . TYR   A 1 120 ? 144.369 144.104 153.259 1.00 44.14  ? 146 TYR   A CZ  1 
ATOM   944  O OH  . TYR   A 1 120 ? 144.850 143.946 151.983 1.00 47.40  ? 146 TYR   A OH  1 
ATOM   945  N N   . TRP   A 1 121 ? 142.878 147.673 157.791 1.00 40.03  ? 147 TRP   A N   1 
ATOM   946  C CA  . TRP   A 1 121 ? 142.946 149.037 157.291 1.00 39.49  ? 147 TRP   A CA  1 
ATOM   947  C C   . TRP   A 1 121 ? 143.917 149.885 158.099 1.00 42.99  ? 147 TRP   A C   1 
ATOM   948  O O   . TRP   A 1 121 ? 144.526 150.806 157.548 1.00 46.65  ? 147 TRP   A O   1 
ATOM   949  C CB  . TRP   A 1 121 ? 141.554 149.654 157.274 1.00 39.61  ? 147 TRP   A CB  1 
ATOM   950  C CG  . TRP   A 1 121 ? 140.757 149.174 156.114 1.00 39.48  ? 147 TRP   A CG  1 
ATOM   951  C CD1 . TRP   A 1 121 ? 139.803 148.203 156.118 1.00 44.22  ? 147 TRP   A CD1 1 
ATOM   952  C CD2 . TRP   A 1 121 ? 140.860 149.629 154.764 1.00 41.04  ? 147 TRP   A CD2 1 
ATOM   953  N NE1 . TRP   A 1 121 ? 139.299 148.030 154.855 1.00 47.15  ? 147 TRP   A NE1 1 
ATOM   954  C CE2 . TRP   A 1 121 ? 139.933 148.896 154.004 1.00 46.07  ? 147 TRP   A CE2 1 
ATOM   955  C CE3 . TRP   A 1 121 ? 141.646 150.590 154.124 1.00 43.27  ? 147 TRP   A CE3 1 
ATOM   956  C CZ2 . TRP   A 1 121 ? 139.768 149.095 152.638 1.00 45.96  ? 147 TRP   A CZ2 1 
ATOM   957  C CZ3 . TRP   A 1 121 ? 141.480 150.785 152.770 1.00 43.37  ? 147 TRP   A CZ3 1 
ATOM   958  C CH2 . TRP   A 1 121 ? 140.551 150.042 152.042 1.00 42.50  ? 147 TRP   A CH2 1 
ATOM   959  N N   . TYR   A 1 122 ? 144.082 149.596 159.392 1.00 41.40  ? 148 TYR   A N   1 
ATOM   960  C CA  . TYR   A 1 122 ? 145.121 150.279 160.160 1.00 41.29  ? 148 TYR   A CA  1 
ATOM   961  C C   . TYR   A 1 122 ? 146.493 150.029 159.551 1.00 45.31  ? 148 TYR   A C   1 
ATOM   962  O O   . TYR   A 1 122 ? 147.262 150.968 159.308 1.00 50.63  ? 148 TYR   A O   1 
ATOM   963  C CB  . TYR   A 1 122 ? 145.090 149.813 161.612 1.00 41.04  ? 148 TYR   A CB  1 
ATOM   964  C CG  . TYR   A 1 122 ? 146.092 150.508 162.503 1.00 45.11  ? 148 TYR   A CG  1 
ATOM   965  C CD1 . TYR   A 1 122 ? 145.865 151.793 162.964 1.00 51.77  ? 148 TYR   A CD1 1 
ATOM   966  C CD2 . TYR   A 1 122 ? 147.256 149.872 162.895 1.00 46.37  ? 148 TYR   A CD2 1 
ATOM   967  C CE1 . TYR   A 1 122 ? 146.774 152.427 163.783 1.00 52.33  ? 148 TYR   A CE1 1 
ATOM   968  C CE2 . TYR   A 1 122 ? 148.168 150.498 163.713 1.00 48.51  ? 148 TYR   A CE2 1 
ATOM   969  C CZ  . TYR   A 1 122 ? 147.923 151.774 164.153 1.00 52.31  ? 148 TYR   A CZ  1 
ATOM   970  O OH  . TYR   A 1 122 ? 148.833 152.403 164.968 1.00 59.22  ? 148 TYR   A OH  1 
ATOM   971  N N   . VAL   A 1 123 ? 146.805 148.763 159.272 1.00 45.18  ? 149 VAL   A N   1 
ATOM   972  C CA  . VAL   A 1 123 ? 148.084 148.429 158.651 1.00 45.30  ? 149 VAL   A CA  1 
ATOM   973  C C   . VAL   A 1 123 ? 148.186 149.060 157.267 1.00 45.63  ? 149 VAL   A C   1 
ATOM   974  O O   . VAL   A 1 123 ? 149.246 149.563 156.875 1.00 49.40  ? 149 VAL   A O   1 
ATOM   975  C CB  . VAL   A 1 123 ? 148.268 146.901 158.589 1.00 43.82  ? 149 VAL   A CB  1 
ATOM   976  C CG1 . VAL   A 1 123 ? 149.518 146.544 157.798 1.00 46.10  ? 149 VAL   A CG1 1 
ATOM   977  C CG2 . VAL   A 1 123 ? 148.342 146.316 159.985 1.00 42.56  ? 149 VAL   A CG2 1 
ATOM   978  N N   . PHE   A 1 124 ? 147.091 149.035 156.503 1.00 43.53  ? 150 PHE   A N   1 
ATOM   979  C CA  . PHE   A 1 124 ? 147.112 149.564 155.144 1.00 42.38  ? 150 PHE   A CA  1 
ATOM   980  C C   . PHE   A 1 124 ? 147.398 151.060 155.129 1.00 44.53  ? 150 PHE   A C   1 
ATOM   981  O O   . PHE   A 1 124 ? 148.185 151.539 154.305 1.00 47.72  ? 150 PHE   A O   1 
ATOM   982  C CB  . PHE   A 1 124 ? 145.782 149.262 154.456 1.00 44.38  ? 150 PHE   A CB  1 
ATOM   983  C CG  . PHE   A 1 124 ? 145.775 149.558 152.988 1.00 43.81  ? 150 PHE   A CG  1 
ATOM   984  C CD1 . PHE   A 1 124 ? 146.325 148.667 152.088 1.00 46.43  ? 150 PHE   A CD1 1 
ATOM   985  C CD2 . PHE   A 1 124 ? 145.202 150.716 152.506 1.00 42.54  ? 150 PHE   A CD2 1 
ATOM   986  C CE1 . PHE   A 1 124 ? 146.316 148.933 150.741 1.00 47.37  ? 150 PHE   A CE1 1 
ATOM   987  C CE2 . PHE   A 1 124 ? 145.193 150.987 151.159 1.00 43.06  ? 150 PHE   A CE2 1 
ATOM   988  C CZ  . PHE   A 1 124 ? 145.749 150.094 150.275 1.00 45.86  ? 150 PHE   A CZ  1 
ATOM   989  N N   . LEU   A 1 125 ? 146.771 151.818 156.031 1.00 45.99  ? 151 LEU   A N   1 
ATOM   990  C CA  . LEU   A 1 125 ? 146.983 153.259 156.090 1.00 44.27  ? 151 LEU   A CA  1 
ATOM   991  C C   . LEU   A 1 125 ? 148.255 153.648 156.828 1.00 44.39  ? 151 LEU   A C   1 
ATOM   992  O O   . LEU   A 1 125 ? 148.686 154.798 156.707 1.00 46.79  ? 151 LEU   A O   1 
ATOM   993  C CB  . LEU   A 1 125 ? 145.792 153.951 156.762 1.00 43.43  ? 151 LEU   A CB  1 
ATOM   994  C CG  . LEU   A 1 125 ? 144.410 153.838 156.111 1.00 44.99  ? 151 LEU   A CG  1 
ATOM   995  C CD1 . LEU   A 1 125 ? 143.400 154.631 156.912 1.00 45.31  ? 151 LEU   A CD1 1 
ATOM   996  C CD2 . LEU   A 1 125 ? 144.419 154.305 154.670 1.00 46.67  ? 151 LEU   A CD2 1 
ATOM   997  N N   . LEU   A 1 126 ? 148.868 152.736 157.585 1.00 46.45  ? 152 LEU   A N   1 
ATOM   998  C CA  . LEU   A 1 126 ? 150.073 153.102 158.324 1.00 44.79  ? 152 LEU   A CA  1 
ATOM   999  C C   . LEU   A 1 126 ? 151.259 153.356 157.401 1.00 49.87  ? 152 LEU   A C   1 
ATOM   1000 O O   . LEU   A 1 126 ? 152.157 154.125 157.759 1.00 54.84  ? 152 LEU   A O   1 
ATOM   1001 C CB  . LEU   A 1 126 ? 150.438 152.010 159.332 1.00 48.41  ? 152 LEU   A CB  1 
ATOM   1002 C CG  . LEU   A 1 126 ? 150.803 152.471 160.743 1.00 54.47  ? 152 LEU   A CG  1 
ATOM   1003 C CD1 . LEU   A 1 126 ? 151.167 151.272 161.595 1.00 54.51  ? 152 LEU   A CD1 1 
ATOM   1004 C CD2 . LEU   A 1 126 ? 151.940 153.483 160.733 1.00 55.31  ? 152 LEU   A CD2 1 
ATOM   1005 N N   . ASP   A 1 127 ? 151.287 152.727 156.226 1.00 49.39  ? 153 ASP   A N   1 
ATOM   1006 C CA  . ASP   A 1 127 ? 152.440 152.793 155.334 1.00 47.81  ? 153 ASP   A CA  1 
ATOM   1007 C C   . ASP   A 1 127 ? 151.969 152.905 153.894 1.00 49.80  ? 153 ASP   A C   1 
ATOM   1008 O O   . ASP   A 1 127 ? 151.169 152.084 153.436 1.00 51.73  ? 153 ASP   A O   1 
ATOM   1009 C CB  . ASP   A 1 127 ? 153.324 151.554 155.500 1.00 51.77  ? 153 ASP   A CB  1 
ATOM   1010 C CG  . ASP   A 1 127 ? 154.737 151.774 155.002 1.00 61.86  ? 153 ASP   A CG  1 
ATOM   1011 O OD1 . ASP   A 1 127 ? 154.929 152.602 154.086 1.00 60.84  ? 153 ASP   A OD1 1 
ATOM   1012 O OD2 . ASP   A 1 127 ? 155.661 151.119 155.527 1.00 68.69  ? 153 ASP   A OD2 1 
ATOM   1013 N N   . LYS   A 1 128 ? 152.467 153.919 153.189 1.00 48.75  ? 154 LYS   A N   1 
ATOM   1014 C CA  . LYS   A 1 128 ? 152.155 154.124 151.782 1.00 45.64  ? 154 LYS   A CA  1 
ATOM   1015 C C   . LYS   A 1 128 ? 153.084 153.369 150.840 1.00 47.03  ? 154 LYS   A C   1 
ATOM   1016 O O   . LYS   A 1 128 ? 152.817 153.334 149.636 1.00 50.19  ? 154 LYS   A O   1 
ATOM   1017 C CB  . LYS   A 1 128 ? 152.209 155.617 151.446 1.00 44.10  ? 154 LYS   A CB  1 
ATOM   1018 C CG  . LYS   A 1 128 ? 151.121 156.433 152.117 1.00 44.65  ? 154 LYS   A CG  1 
ATOM   1019 C CD  . LYS   A 1 128 ? 151.105 157.877 151.640 1.00 44.19  ? 154 LYS   A CD  1 
ATOM   1020 C CE  . LYS   A 1 128 ? 152.264 158.670 152.203 1.00 48.37  ? 154 LYS   A CE  1 
ATOM   1021 N NZ  . LYS   A 1 128 ? 152.167 160.114 151.867 1.00 50.92  ? 154 LYS   A NZ  1 
ATOM   1022 N N   . THR   A 1 129 ? 154.158 152.769 151.347 1.00 46.77  ? 155 THR   A N   1 
ATOM   1023 C CA  . THR   A 1 129 ? 155.099 152.038 150.512 1.00 47.47  ? 155 THR   A CA  1 
ATOM   1024 C C   . THR   A 1 129 ? 154.700 150.587 150.283 1.00 52.68  ? 155 THR   A C   1 
ATOM   1025 O O   . THR   A 1 129 ? 155.350 149.908 149.481 1.00 60.47  ? 155 THR   A O   1 
ATOM   1026 C CB  . THR   A 1 129 ? 156.496 152.068 151.137 1.00 51.93  ? 155 THR   A CB  1 
ATOM   1027 O OG1 . THR   A 1 129 ? 156.421 151.677 152.512 1.00 57.40  ? 155 THR   A OG1 1 
ATOM   1028 C CG2 . THR   A 1 129 ? 157.100 153.452 151.041 1.00 50.14  ? 155 THR   A CG2 1 
ATOM   1029 N N   . SER   A 1 130 ? 153.658 150.100 150.957 1.00 51.07  ? 156 SER   A N   1 
ATOM   1030 C CA  . SER   A 1 130 ? 153.183 148.728 150.822 1.00 51.25  ? 156 SER   A CA  1 
ATOM   1031 C C   . SER   A 1 130 ? 151.813 148.668 150.155 1.00 49.23  ? 156 SER   A C   1 
ATOM   1032 O O   . SER   A 1 130 ? 151.056 147.719 150.369 1.00 51.25  ? 156 SER   A O   1 
ATOM   1033 C CB  . SER   A 1 130 ? 153.135 148.051 152.189 1.00 57.85  ? 156 SER   A CB  1 
ATOM   1034 O OG  . SER   A 1 130 ? 152.222 148.710 153.049 1.00 63.83  ? 156 SER   A OG  1 
ATOM   1035 N N   . TRP   A 1 131 ? 151.483 149.673 149.349 1.00 46.82  ? 157 TRP   A N   1 
ATOM   1036 C CA  . TRP   A 1 131 ? 150.195 149.742 148.673 1.00 45.40  ? 157 TRP   A CA  1 
ATOM   1037 C C   . TRP   A 1 131 ? 150.280 149.079 147.307 1.00 47.47  ? 157 TRP   A C   1 
ATOM   1038 O O   . TRP   A 1 131 ? 151.208 149.339 146.537 1.00 50.81  ? 157 TRP   A O   1 
ATOM   1039 C CB  . TRP   A 1 131 ? 149.741 151.190 148.505 1.00 40.86  ? 157 TRP   A CB  1 
ATOM   1040 C CG  . TRP   A 1 131 ? 149.202 151.824 149.736 1.00 41.21  ? 157 TRP   A CG  1 
ATOM   1041 C CD1 . TRP   A 1 131 ? 149.423 151.442 151.021 1.00 45.68  ? 157 TRP   A CD1 1 
ATOM   1042 C CD2 . TRP   A 1 131 ? 148.342 152.965 149.799 1.00 40.82  ? 157 TRP   A CD2 1 
ATOM   1043 N NE1 . TRP   A 1 131 ? 148.756 152.274 151.884 1.00 47.21  ? 157 TRP   A NE1 1 
ATOM   1044 C CE2 . TRP   A 1 131 ? 148.083 153.218 151.155 1.00 40.85  ? 157 TRP   A CE2 1 
ATOM   1045 C CE3 . TRP   A 1 131 ? 147.766 153.796 148.837 1.00 42.85  ? 157 TRP   A CE3 1 
ATOM   1046 C CZ2 . TRP   A 1 131 ? 147.275 154.266 151.575 1.00 39.24  ? 157 TRP   A CZ2 1 
ATOM   1047 C CZ3 . TRP   A 1 131 ? 146.965 154.835 149.257 1.00 43.90  ? 157 TRP   A CZ3 1 
ATOM   1048 C CH2 . TRP   A 1 131 ? 146.727 155.061 150.613 1.00 41.22  ? 157 TRP   A CH2 1 
ATOM   1049 N N   . ASN   A 1 132 ? 149.302 148.232 147.013 1.00 43.07  ? 158 ASN   A N   1 
ATOM   1050 C CA  . ASN   A 1 132 ? 149.126 147.675 145.684 1.00 39.10  ? 158 ASN   A CA  1 
ATOM   1051 C C   . ASN   A 1 132 ? 147.650 147.355 145.512 1.00 45.67  ? 158 ASN   A C   1 
ATOM   1052 O O   . ASN   A 1 132 ? 146.877 147.360 146.474 1.00 52.26  ? 158 ASN   A O   1 
ATOM   1053 C CB  . ASN   A 1 132 ? 150.003 146.441 145.459 1.00 40.50  ? 158 ASN   A CB  1 
ATOM   1054 C CG  . ASN   A 1 132 ? 150.024 145.513 146.648 1.00 43.73  ? 158 ASN   A CG  1 
ATOM   1055 O OD1 . ASN   A 1 132 ? 148.989 144.989 147.058 1.00 49.57  ? 158 ASN   A OD1 1 
ATOM   1056 N ND2 . ASN   A 1 132 ? 151.207 145.285 147.201 1.00 43.56  ? 158 ASN   A ND2 1 
ATOM   1057 N N   . ASN   A 1 133 ? 147.260 147.089 144.266 1.00 45.34  ? 159 ASN   A N   1 
ATOM   1058 C CA  . ASN   A 1 133 ? 145.844 146.943 143.953 1.00 43.44  ? 159 ASN   A CA  1 
ATOM   1059 C C   . ASN   A 1 133 ? 145.232 145.733 144.649 1.00 42.89  ? 159 ASN   A C   1 
ATOM   1060 O O   . ASN   A 1 133 ? 144.077 145.782 145.088 1.00 46.97  ? 159 ASN   A O   1 
ATOM   1061 C CB  . ASN   A 1 133 ? 145.655 146.850 142.443 1.00 45.38  ? 159 ASN   A CB  1 
ATOM   1062 C CG  . ASN   A 1 133 ? 146.081 148.114 141.727 1.00 48.03  ? 159 ASN   A CG  1 
ATOM   1063 O OD1 . ASN   A 1 133 ? 145.328 149.081 141.654 1.00 49.10  ? 159 ASN   A OD1 1 
ATOM   1064 N ND2 . ASN   A 1 133 ? 147.294 148.112 141.194 1.00 51.79  ? 159 ASN   A ND2 1 
ATOM   1065 N N   . HIS   A 1 134 ? 145.985 144.642 144.766 1.00 40.63  ? 160 HIS   A N   1 
ATOM   1066 C CA  . HIS   A 1 134 ? 145.432 143.426 145.344 1.00 44.28  ? 160 HIS   A CA  1 
ATOM   1067 C C   . HIS   A 1 134 ? 145.328 143.472 146.862 1.00 45.63  ? 160 HIS   A C   1 
ATOM   1068 O O   . HIS   A 1 134 ? 144.718 142.569 147.440 1.00 50.52  ? 160 HIS   A O   1 
ATOM   1069 C CB  . HIS   A 1 134 ? 146.248 142.204 144.909 1.00 48.61  ? 160 HIS   A CB  1 
ATOM   1070 C CG  . HIS   A 1 134 ? 147.675 142.217 145.355 1.00 46.75  ? 160 HIS   A CG  1 
ATOM   1071 N ND1 . HIS   A 1 134 ? 148.700 142.662 144.550 1.00 48.01  ? 160 HIS   A ND1 1 
ATOM   1072 C CD2 . HIS   A 1 134 ? 148.255 141.800 146.504 1.00 46.37  ? 160 HIS   A CD2 1 
ATOM   1073 C CE1 . HIS   A 1 134 ? 149.847 142.538 145.192 1.00 46.84  ? 160 HIS   A CE1 1 
ATOM   1074 N NE2 . HIS   A 1 134 ? 149.605 142.020 146.381 1.00 47.73  ? 160 HIS   A NE2 1 
ATOM   1075 N N   . SER   A 1 135 ? 145.893 144.485 147.521 1.00 42.17  ? 161 SER   A N   1 
ATOM   1076 C CA  . SER   A 1 135 ? 145.606 144.732 148.930 1.00 41.73  ? 161 SER   A CA  1 
ATOM   1077 C C   . SER   A 1 135 ? 144.368 145.604 149.102 1.00 43.15  ? 161 SER   A C   1 
ATOM   1078 O O   . SER   A 1 135 ? 143.549 145.363 150.002 1.00 49.09  ? 161 SER   A O   1 
ATOM   1079 C CB  . SER   A 1 135 ? 146.807 145.398 149.602 1.00 42.26  ? 161 SER   A CB  1 
ATOM   1080 O OG  . SER   A 1 135 ? 147.951 144.568 149.537 1.00 46.83  ? 161 SER   A OG  1 
ATOM   1081 N N   . TYR   A 1 136 ? 144.221 146.609 148.238 1.00 40.51  ? 162 TYR   A N   1 
ATOM   1082 C CA  . TYR   A 1 136 ? 143.008 147.414 148.224 1.00 43.28  ? 162 TYR   A CA  1 
ATOM   1083 C C   . TYR   A 1 136 ? 141.788 146.547 147.952 1.00 48.19  ? 162 TYR   A C   1 
ATOM   1084 O O   . TYR   A 1 136 ? 140.726 146.746 148.555 1.00 52.35  ? 162 TYR   A O   1 
ATOM   1085 C CB  . TYR   A 1 136 ? 143.146 148.517 147.174 1.00 47.23  ? 162 TYR   A CB  1 
ATOM   1086 C CG  . TYR   A 1 136 ? 142.014 149.517 147.127 1.00 49.24  ? 162 TYR   A CG  1 
ATOM   1087 C CD1 . TYR   A 1 136 ? 141.793 150.396 148.174 1.00 48.11  ? 162 TYR   A CD1 1 
ATOM   1088 C CD2 . TYR   A 1 136 ? 141.187 149.602 146.019 1.00 50.54  ? 162 TYR   A CD2 1 
ATOM   1089 C CE1 . TYR   A 1 136 ? 140.768 151.317 148.127 1.00 47.95  ? 162 TYR   A CE1 1 
ATOM   1090 C CE2 . TYR   A 1 136 ? 140.162 150.520 145.963 1.00 52.90  ? 162 TYR   A CE2 1 
ATOM   1091 C CZ  . TYR   A 1 136 ? 139.955 151.374 147.019 1.00 53.47  ? 162 TYR   A CZ  1 
ATOM   1092 O OH  . TYR   A 1 136 ? 138.931 152.291 146.966 1.00 56.32  ? 162 TYR   A OH  1 
ATOM   1093 N N   . LEU   A 1 137 ? 141.922 145.568 147.054 1.00 46.81  ? 163 LEU   A N   1 
ATOM   1094 C CA  . LEU   A 1 137 ? 140.801 144.681 146.762 1.00 44.97  ? 163 LEU   A CA  1 
ATOM   1095 C C   . LEU   A 1 137 ? 140.426 143.847 147.980 1.00 44.90  ? 163 LEU   A C   1 
ATOM   1096 O O   . LEU   A 1 137 ? 139.239 143.640 148.253 1.00 46.72  ? 163 LEU   A O   1 
ATOM   1097 C CB  . LEU   A 1 137 ? 141.136 143.777 145.578 1.00 44.80  ? 163 LEU   A CB  1 
ATOM   1098 C CG  . LEU   A 1 137 ? 139.994 142.917 145.031 1.00 48.13  ? 163 LEU   A CG  1 
ATOM   1099 C CD1 . LEU   A 1 137 ? 138.906 143.777 144.407 1.00 49.73  ? 163 LEU   A CD1 1 
ATOM   1100 C CD2 . LEU   A 1 137 ? 140.526 141.921 144.027 1.00 50.18  ? 163 LEU   A CD2 1 
ATOM   1101 N N   . TYR   A 1 138 ? 141.419 143.348 148.718 1.00 42.89  ? 164 TYR   A N   1 
ATOM   1102 C CA  . TYR   A 1 138 ? 141.115 142.565 149.911 1.00 40.25  ? 164 TYR   A CA  1 
ATOM   1103 C C   . TYR   A 1 138 ? 140.413 143.425 150.951 1.00 42.39  ? 164 TYR   A C   1 
ATOM   1104 O O   . TYR   A 1 138 ? 139.459 142.977 151.601 1.00 45.89  ? 164 TYR   A O   1 
ATOM   1105 C CB  . TYR   A 1 138 ? 142.388 141.961 150.506 1.00 40.48  ? 164 TYR   A CB  1 
ATOM   1106 C CG  . TYR   A 1 138 ? 143.215 141.083 149.583 1.00 41.66  ? 164 TYR   A CG  1 
ATOM   1107 C CD1 . TYR   A 1 138 ? 142.684 140.537 148.421 1.00 47.32  ? 164 TYR   A CD1 1 
ATOM   1108 C CD2 . TYR   A 1 138 ? 144.536 140.795 149.887 1.00 43.02  ? 164 TYR   A CD2 1 
ATOM   1109 C CE1 . TYR   A 1 138 ? 143.449 139.747 147.592 1.00 53.27  ? 164 TYR   A CE1 1 
ATOM   1110 C CE2 . TYR   A 1 138 ? 145.305 140.003 149.063 1.00 48.41  ? 164 TYR   A CE2 1 
ATOM   1111 C CZ  . TYR   A 1 138 ? 144.758 139.482 147.919 1.00 55.32  ? 164 TYR   A CZ  1 
ATOM   1112 O OH  . TYR   A 1 138 ? 145.524 138.690 147.099 1.00 58.10  ? 164 TYR   A OH  1 
ATOM   1113 N N   . GLY   A 1 139 ? 140.869 144.667 151.117 1.00 41.75  ? 165 GLY   A N   1 
ATOM   1114 C CA  . GLY   A 1 139 ? 140.194 145.571 152.034 1.00 40.95  ? 165 GLY   A CA  1 
ATOM   1115 C C   . GLY   A 1 139 ? 138.753 145.830 151.640 1.00 45.03  ? 165 GLY   A C   1 
ATOM   1116 O O   . GLY   A 1 139 ? 137.850 145.799 152.483 1.00 46.73  ? 165 GLY   A O   1 
ATOM   1117 N N   . LEU   A 1 140 ? 138.513 146.073 150.348 1.00 44.94  ? 166 LEU   A N   1 
ATOM   1118 C CA  . LEU   A 1 140 ? 137.151 146.299 149.880 1.00 41.85  ? 166 LEU   A CA  1 
ATOM   1119 C C   . LEU   A 1 140 ? 136.275 145.072 150.092 1.00 44.72  ? 166 LEU   A C   1 
ATOM   1120 O O   . LEU   A 1 140 ? 135.115 145.194 150.500 1.00 47.18  ? 166 LEU   A O   1 
ATOM   1121 C CB  . LEU   A 1 140 ? 137.150 146.686 148.401 1.00 42.73  ? 166 LEU   A CB  1 
ATOM   1122 C CG  . LEU   A 1 140 ? 137.714 148.037 147.957 1.00 48.71  ? 166 LEU   A CG  1 
ATOM   1123 C CD1 . LEU   A 1 140 ? 137.446 148.219 146.476 1.00 50.80  ? 166 LEU   A CD1 1 
ATOM   1124 C CD2 . LEU   A 1 140 ? 137.144 149.204 148.751 1.00 48.22  ? 166 LEU   A CD2 1 
ATOM   1125 N N   . LEU   A 1 141 ? 136.798 143.882 149.794 1.00 43.37  ? 167 LEU   A N   1 
ATOM   1126 C CA  . LEU   A 1 141 ? 136.002 142.672 149.965 1.00 39.63  ? 167 LEU   A CA  1 
ATOM   1127 C C   . LEU   A 1 141 ? 135.668 142.440 151.431 1.00 38.51  ? 167 LEU   A C   1 
ATOM   1128 O O   . LEU   A 1 141 ? 134.544 142.049 151.765 1.00 44.33  ? 167 LEU   A O   1 
ATOM   1129 C CB  . LEU   A 1 141 ? 136.736 141.465 149.382 1.00 41.74  ? 167 LEU   A CB  1 
ATOM   1130 C CG  . LEU   A 1 141 ? 136.896 141.388 147.860 1.00 43.98  ? 167 LEU   A CG  1 
ATOM   1131 C CD1 . LEU   A 1 141 ? 137.713 140.169 147.487 1.00 44.82  ? 167 LEU   A CD1 1 
ATOM   1132 C CD2 . LEU   A 1 141 ? 135.556 141.354 147.150 1.00 45.62  ? 167 LEU   A CD2 1 
ATOM   1133 N N   . ALA   A 1 142 ? 136.630 142.675 152.324 1.00 40.26  ? 168 ALA   A N   1 
ATOM   1134 C CA  . ALA   A 1 142 ? 136.353 142.542 153.749 1.00 42.15  ? 168 ALA   A CA  1 
ATOM   1135 C C   . ALA   A 1 142 ? 135.302 143.546 154.200 1.00 41.29  ? 168 ALA   A C   1 
ATOM   1136 O O   . ALA   A 1 142 ? 134.444 143.226 155.029 1.00 44.11  ? 168 ALA   A O   1 
ATOM   1137 C CB  . ALA   A 1 142 ? 137.640 142.716 154.553 1.00 45.20  ? 168 ALA   A CB  1 
ATOM   1138 N N   . PHE   A 1 143 ? 135.358 144.773 153.674 1.00 43.07  ? 169 PHE   A N   1 
ATOM   1139 C CA  . PHE   A 1 143 ? 134.339 145.763 154.011 1.00 41.51  ? 169 PHE   A CA  1 
ATOM   1140 C C   . PHE   A 1 143 ? 132.958 145.330 153.532 1.00 45.53  ? 169 PHE   A C   1 
ATOM   1141 O O   . PHE   A 1 143 ? 131.971 145.455 154.265 1.00 48.32  ? 169 PHE   A O   1 
ATOM   1142 C CB  . PHE   A 1 143 ? 134.704 147.114 153.406 1.00 40.25  ? 169 PHE   A CB  1 
ATOM   1143 C CG  . PHE   A 1 143 ? 133.718 148.198 153.712 1.00 40.21  ? 169 PHE   A CG  1 
ATOM   1144 C CD1 . PHE   A 1 143 ? 133.651 148.750 154.974 1.00 43.27  ? 169 PHE   A CD1 1 
ATOM   1145 C CD2 . PHE   A 1 143 ? 132.869 148.676 152.735 1.00 44.24  ? 169 PHE   A CD2 1 
ATOM   1146 C CE1 . PHE   A 1 143 ? 132.751 149.750 155.257 1.00 43.31  ? 169 PHE   A CE1 1 
ATOM   1147 C CE2 . PHE   A 1 143 ? 131.968 149.678 153.013 1.00 44.92  ? 169 PHE   A CE2 1 
ATOM   1148 C CZ  . PHE   A 1 143 ? 131.909 150.215 154.275 1.00 44.30  ? 169 PHE   A CZ  1 
ATOM   1149 N N   . GLN   A 1 144 ? 132.867 144.834 152.296 1.00 46.10  ? 170 GLN   A N   1 
ATOM   1150 C CA  . GLN   A 1 144 ? 131.579 144.406 151.756 1.00 42.68  ? 170 GLN   A CA  1 
ATOM   1151 C C   . GLN   A 1 144 ? 131.008 143.244 152.553 1.00 43.75  ? 170 GLN   A C   1 
ATOM   1152 O O   . GLN   A 1 144 ? 129.836 143.259 152.946 1.00 47.43  ? 170 GLN   A O   1 
ATOM   1153 C CB  . GLN   A 1 144 ? 131.728 144.004 150.292 1.00 41.04  ? 170 GLN   A CB  1 
ATOM   1154 C CG  . GLN   A 1 144 ? 132.043 145.129 149.347 1.00 42.32  ? 170 GLN   A CG  1 
ATOM   1155 C CD  . GLN   A 1 144 ? 132.355 144.619 147.964 1.00 47.16  ? 170 GLN   A CD  1 
ATOM   1156 O OE1 . GLN   A 1 144 ? 131.971 143.509 147.603 1.00 47.09  ? 170 GLN   A OE1 1 
ATOM   1157 N NE2 . GLN   A 1 144 ? 133.063 145.420 147.181 1.00 51.10  ? 170 GLN   A NE2 1 
ATOM   1158 N N   . LEU   A 1 145 ? 131.826 142.221 152.801 1.00 42.92  ? 171 LEU   A N   1 
ATOM   1159 C CA  . LEU   A 1 145 ? 131.348 141.006 153.448 1.00 40.90  ? 171 LEU   A CA  1 
ATOM   1160 C C   . LEU   A 1 145 ? 130.930 141.225 154.896 1.00 43.19  ? 171 LEU   A C   1 
ATOM   1161 O O   . LEU   A 1 145 ? 130.271 140.349 155.465 1.00 51.05  ? 171 LEU   A O   1 
ATOM   1162 C CB  . LEU   A 1 145 ? 132.423 139.919 153.376 1.00 40.62  ? 171 LEU   A CB  1 
ATOM   1163 C CG  . LEU   A 1 145 ? 132.343 138.971 152.176 1.00 41.81  ? 171 LEU   A CG  1 
ATOM   1164 C CD1 . LEU   A 1 145 ? 132.535 139.691 150.856 1.00 43.15  ? 171 LEU   A CD1 1 
ATOM   1165 C CD2 . LEU   A 1 145 ? 133.371 137.865 152.315 1.00 45.07  ? 171 LEU   A CD2 1 
ATOM   1166 N N   . THR   A 1 146 ? 131.293 142.354 155.507 1.00 37.76  ? 172 THR   A N   1 
ATOM   1167 C CA  . THR   A 1 146 ? 130.852 142.626 156.869 1.00 39.17  ? 172 THR   A CA  1 
ATOM   1168 C C   . THR   A 1 146 ? 129.338 142.746 156.955 1.00 45.66  ? 172 THR   A C   1 
ATOM   1169 O O   . THR   A 1 146 ? 128.748 142.393 157.982 1.00 50.37  ? 172 THR   A O   1 
ATOM   1170 C CB  . THR   A 1 146 ? 131.505 143.904 157.390 1.00 43.75  ? 172 THR   A CB  1 
ATOM   1171 O OG1 . THR   A 1 146 ? 132.929 143.749 157.401 1.00 49.96  ? 172 THR   A OG1 1 
ATOM   1172 C CG2 . THR   A 1 146 ? 131.024 144.217 158.793 1.00 43.17  ? 172 THR   A CG2 1 
ATOM   1173 N N   . PHE   A 1 147 ? 128.693 143.229 155.891 1.00 46.87  ? 173 PHE   A N   1 
ATOM   1174 C CA  . PHE   A 1 147 ? 127.252 143.441 155.884 1.00 42.13  ? 173 PHE   A CA  1 
ATOM   1175 C C   . PHE   A 1 147 ? 126.474 142.314 155.224 1.00 39.76  ? 173 PHE   A C   1 
ATOM   1176 O O   . PHE   A 1 147 ? 125.273 142.183 155.480 1.00 43.97  ? 173 PHE   A O   1 
ATOM   1177 C CB  . PHE   A 1 147 ? 126.911 144.751 155.167 1.00 39.67  ? 173 PHE   A CB  1 
ATOM   1178 C CG  . PHE   A 1 147 ? 127.490 145.967 155.824 1.00 40.91  ? 173 PHE   A CG  1 
ATOM   1179 C CD1 . PHE   A 1 147 ? 127.016 146.397 157.047 1.00 43.16  ? 173 PHE   A CD1 1 
ATOM   1180 C CD2 . PHE   A 1 147 ? 128.500 146.685 155.216 1.00 44.06  ? 173 PHE   A CD2 1 
ATOM   1181 C CE1 . PHE   A 1 147 ? 127.544 147.514 157.652 1.00 45.70  ? 173 PHE   A CE1 1 
ATOM   1182 C CE2 . PHE   A 1 147 ? 129.031 147.803 155.817 1.00 44.47  ? 173 PHE   A CE2 1 
ATOM   1183 C CZ  . PHE   A 1 147 ? 128.552 148.218 157.035 1.00 43.67  ? 173 PHE   A CZ  1 
ATOM   1184 N N   . MET   A 1 148 ? 127.114 141.505 154.389 1.00 37.90  ? 174 MET   A N   1 
ATOM   1185 C CA  . MET   A 1 148 ? 126.403 140.455 153.678 1.00 43.93  ? 174 MET   A CA  1 
ATOM   1186 C C   . MET   A 1 148 ? 126.079 139.290 154.604 1.00 49.27  ? 174 MET   A C   1 
ATOM   1187 O O   . MET   A 1 148 ? 126.870 138.930 155.481 1.00 49.53  ? 174 MET   A O   1 
ATOM   1188 C CB  . MET   A 1 148 ? 127.237 139.975 152.495 1.00 42.86  ? 174 MET   A CB  1 
ATOM   1189 C CG  . MET   A 1 148 ? 127.521 141.072 151.498 1.00 44.45  ? 174 MET   A CG  1 
ATOM   1190 S SD  . MET   A 1 148 ? 128.407 140.501 150.050 1.00 52.94  ? 174 MET   A SD  1 
ATOM   1191 C CE  . MET   A 1 148 ? 128.555 142.040 149.159 1.00 47.16  ? 174 MET   A CE  1 
ATOM   1192 N N   . ASP   A 1 149 ? 124.900 138.699 154.403 1.00 46.57  ? 175 ASP   A N   1 
ATOM   1193 C CA  . ASP   A 1 149 ? 124.449 137.556 155.194 1.00 43.81  ? 175 ASP   A CA  1 
ATOM   1194 C C   . ASP   A 1 149 ? 125.017 136.287 154.570 1.00 45.31  ? 175 ASP   A C   1 
ATOM   1195 O O   . ASP   A 1 149 ? 124.322 135.506 153.918 1.00 47.50  ? 175 ASP   A O   1 
ATOM   1196 C CB  . ASP   A 1 149 ? 122.928 137.516 155.260 1.00 45.87  ? 175 ASP   A CB  1 
ATOM   1197 C CG  . ASP   A 1 149 ? 122.336 138.790 155.824 1.00 53.66  ? 175 ASP   A CG  1 
ATOM   1198 O OD1 . ASP   A 1 149 ? 122.426 139.838 155.153 1.00 52.11  ? 175 ASP   A OD1 1 
ATOM   1199 O OD2 . ASP   A 1 149 ? 121.777 138.743 156.939 1.00 59.72  ? 175 ASP   A OD2 1 
ATOM   1200 N N   . ALA   A 1 150 ? 126.315 136.086 154.782 1.00 41.78  ? 176 ALA   A N   1 
ATOM   1201 C CA  . ALA   A 1 150 ? 127.039 134.958 154.213 1.00 38.22  ? 176 ALA   A CA  1 
ATOM   1202 C C   . ALA   A 1 150 ? 127.138 133.763 155.153 1.00 36.61  ? 176 ALA   A C   1 
ATOM   1203 O O   . ALA   A 1 150 ? 127.666 132.725 154.747 1.00 38.20  ? 176 ALA   A O   1 
ATOM   1204 C CB  . ALA   A 1 150 ? 128.445 135.400 153.803 1.00 39.85  ? 176 ALA   A CB  1 
ATOM   1205 N N   . ASN   A 1 151 ? 126.637 133.872 156.385 1.00 35.98  ? 177 ASN   A N   1 
ATOM   1206 C CA  . ASN   A 1 151 ? 126.728 132.806 157.374 1.00 34.80  ? 177 ASN   A CA  1 
ATOM   1207 C C   . ASN   A 1 151 ? 125.492 131.920 157.392 1.00 44.60  ? 177 ASN   A C   1 
ATOM   1208 O O   . ASN   A 1 151 ? 125.195 131.307 158.423 1.00 46.93  ? 177 ASN   A O   1 
ATOM   1209 C CB  . ASN   A 1 151 ? 126.967 133.396 158.764 1.00 32.60  ? 177 ASN   A CB  1 
ATOM   1210 C CG  . ASN   A 1 151 ? 125.811 134.238 159.247 1.00 41.23  ? 177 ASN   A CG  1 
ATOM   1211 O OD1 . ASN   A 1 151 ? 125.041 134.771 158.451 1.00 45.70  ? 177 ASN   A OD1 1 
ATOM   1212 N ND2 . ASN   A 1 151 ? 125.685 134.370 160.561 1.00 48.51  ? 177 ASN   A ND2 1 
ATOM   1213 N N   . HIS   A 1 152 ? 124.770 131.837 156.274 1.00 44.72  ? 178 HIS   A N   1 
ATOM   1214 C CA  . HIS   A 1 152 ? 123.547 131.054 156.192 1.00 37.27  ? 178 HIS   A CA  1 
ATOM   1215 C C   . HIS   A 1 152 ? 123.775 129.624 155.731 1.00 36.67  ? 178 HIS   A C   1 
ATOM   1216 O O   . HIS   A 1 152 ? 122.938 128.761 156.017 1.00 43.08  ? 178 HIS   A O   1 
ATOM   1217 C CB  . HIS   A 1 152 ? 122.558 131.733 155.243 1.00 32.82  ? 178 HIS   A CB  1 
ATOM   1218 C CG  . HIS   A 1 152 ? 121.910 132.952 155.819 1.00 34.66  ? 178 HIS   A CG  1 
ATOM   1219 N ND1 . HIS   A 1 152 ? 120.776 133.515 155.279 1.00 38.76  ? 178 HIS   A ND1 1 
ATOM   1220 C CD2 . HIS   A 1 152 ? 122.231 133.710 156.891 1.00 37.43  ? 178 HIS   A CD2 1 
ATOM   1221 C CE1 . HIS   A 1 152 ? 120.426 134.570 155.994 1.00 37.54  ? 178 HIS   A CE1 1 
ATOM   1222 N NE2 . HIS   A 1 152 ? 121.293 134.710 156.978 1.00 38.07  ? 178 HIS   A NE2 1 
ATOM   1223 N N   . TYR   A 1 153 ? 124.874 129.351 155.031 1.00 36.60  ? 179 TYR   A N   1 
ATOM   1224 C CA  . TYR   A 1 153 ? 125.136 128.046 154.440 1.00 40.01  ? 179 TYR   A CA  1 
ATOM   1225 C C   . TYR   A 1 153 ? 126.570 127.640 154.722 1.00 42.18  ? 179 TYR   A C   1 
ATOM   1226 O O   . TYR   A 1 153 ? 127.492 128.436 154.524 1.00 46.04  ? 179 TYR   A O   1 
ATOM   1227 C CB  . TYR   A 1 153 ? 124.887 128.082 152.941 1.00 39.13  ? 179 TYR   A CB  1 
ATOM   1228 C CG  . TYR   A 1 153 ? 124.930 126.743 152.248 1.00 38.23  ? 179 TYR   A CG  1 
ATOM   1229 C CD1 . TYR   A 1 153 ? 123.835 125.901 152.260 1.00 38.93  ? 179 TYR   A CD1 1 
ATOM   1230 C CD2 . TYR   A 1 153 ? 126.057 126.337 151.555 1.00 39.11  ? 179 TYR   A CD2 1 
ATOM   1231 C CE1 . TYR   A 1 153 ? 123.864 124.692 151.617 1.00 41.56  ? 179 TYR   A CE1 1 
ATOM   1232 C CE2 . TYR   A 1 153 ? 126.094 125.127 150.907 1.00 40.57  ? 179 TYR   A CE2 1 
ATOM   1233 C CZ  . TYR   A 1 153 ? 124.995 124.309 150.941 1.00 43.72  ? 179 TYR   A CZ  1 
ATOM   1234 O OH  . TYR   A 1 153 ? 125.029 123.097 150.298 1.00 52.20  ? 179 TYR   A OH  1 
ATOM   1235 N N   . TRP   A 1 154 ? 126.749 126.400 155.169 1.00 38.05  ? 180 TRP   A N   1 
ATOM   1236 C CA  . TRP   A 1 154 ? 128.061 125.850 155.485 1.00 37.48  ? 180 TRP   A CA  1 
ATOM   1237 C C   . TRP   A 1 154 ? 128.778 126.741 156.499 1.00 36.50  ? 180 TRP   A C   1 
ATOM   1238 O O   . TRP   A 1 154 ? 129.893 127.220 156.279 1.00 45.29  ? 180 TRP   A O   1 
ATOM   1239 C CB  . TRP   A 1 154 ? 128.885 125.678 154.201 1.00 38.87  ? 180 TRP   A CB  1 
ATOM   1240 C CG  . TRP   A 1 154 ? 130.017 124.681 154.257 1.00 37.48  ? 180 TRP   A CG  1 
ATOM   1241 C CD1 . TRP   A 1 154 ? 130.162 123.636 155.123 1.00 39.21  ? 180 TRP   A CD1 1 
ATOM   1242 C CD2 . TRP   A 1 154 ? 131.157 124.642 153.393 1.00 37.93  ? 180 TRP   A CD2 1 
ATOM   1243 N NE1 . TRP   A 1 154 ? 131.318 122.953 154.853 1.00 42.85  ? 180 TRP   A NE1 1 
ATOM   1244 C CE2 . TRP   A 1 154 ? 131.949 123.551 153.796 1.00 42.88  ? 180 TRP   A CE2 1 
ATOM   1245 C CE3 . TRP   A 1 154 ? 131.587 125.426 152.321 1.00 40.70  ? 180 TRP   A CE3 1 
ATOM   1246 C CZ2 . TRP   A 1 154 ? 133.146 123.226 153.165 1.00 45.61  ? 180 TRP   A CZ2 1 
ATOM   1247 C CZ3 . TRP   A 1 154 ? 132.773 125.101 151.696 1.00 44.81  ? 180 TRP   A CZ3 1 
ATOM   1248 C CH2 . TRP   A 1 154 ? 133.539 124.011 152.118 1.00 45.87  ? 180 TRP   A CH2 1 
ATOM   1249 N N   . SER   A 1 155 ? 128.103 126.962 157.624 1.00 28.17  ? 181 SER   A N   1 
ATOM   1250 C CA  . SER   A 1 155 ? 128.592 127.836 158.676 1.00 34.59  ? 181 SER   A CA  1 
ATOM   1251 C C   . SER   A 1 155 ? 128.351 127.182 160.025 1.00 38.22  ? 181 SER   A C   1 
ATOM   1252 O O   . SER   A 1 155 ? 127.375 126.452 160.213 1.00 42.72  ? 181 SER   A O   1 
ATOM   1253 C CB  . SER   A 1 155 ? 127.903 129.202 158.636 1.00 42.11  ? 181 SER   A CB  1 
ATOM   1254 O OG  . SER   A 1 155 ? 126.513 129.077 158.879 1.00 46.18  ? 181 SER   A OG  1 
ATOM   1255 N N   . VAL   A 1 156 ? 129.257 127.450 160.967 1.00 34.61  ? 182 VAL   A N   1 
ATOM   1256 C CA  . VAL   A 1 156 ? 129.091 126.916 162.313 1.00 34.00  ? 182 VAL   A CA  1 
ATOM   1257 C C   . VAL   A 1 156 ? 127.941 127.612 163.029 1.00 40.71  ? 182 VAL   A C   1 
ATOM   1258 O O   . VAL   A 1 156 ? 127.274 127.006 163.879 1.00 44.83  ? 182 VAL   A O   1 
ATOM   1259 C CB  . VAL   A 1 156 ? 130.406 127.033 163.101 1.00 31.63  ? 182 VAL   A CB  1 
ATOM   1260 C CG1 . VAL   A 1 156 ? 130.208 126.550 164.525 1.00 38.19  ? 182 VAL   A CG1 1 
ATOM   1261 C CG2 . VAL   A 1 156 ? 131.502 126.237 162.422 1.00 34.37  ? 182 VAL   A CG2 1 
ATOM   1262 N N   . ASP   A 1 157 ? 127.694 128.888 162.717 1.00 41.45  ? 183 ASP   A N   1 
ATOM   1263 C CA  . ASP   A 1 157 ? 126.545 129.581 163.291 1.00 42.61  ? 183 ASP   A CA  1 
ATOM   1264 C C   . ASP   A 1 157 ? 125.239 128.894 162.925 1.00 44.69  ? 183 ASP   A C   1 
ATOM   1265 O O   . ASP   A 1 157 ? 124.277 128.942 163.699 1.00 47.46  ? 183 ASP   A O   1 
ATOM   1266 C CB  . ASP   A 1 157 ? 126.512 131.037 162.829 1.00 38.47  ? 183 ASP   A CB  1 
ATOM   1267 C CG  . ASP   A 1 157 ? 127.490 131.917 163.581 1.00 46.76  ? 183 ASP   A CG  1 
ATOM   1268 O OD1 . ASP   A 1 157 ? 128.130 131.439 164.540 1.00 50.01  ? 183 ASP   A OD1 1 
ATOM   1269 O OD2 . ASP   A 1 157 ? 127.624 133.101 163.209 1.00 53.66  ? 183 ASP   A OD2 1 
ATOM   1270 N N   . GLY   A 1 158 ? 125.180 128.261 161.755 1.00 39.26  ? 184 GLY   A N   1 
ATOM   1271 C CA  . GLY   A 1 158 ? 124.003 127.485 161.414 1.00 39.45  ? 184 GLY   A CA  1 
ATOM   1272 C C   . GLY   A 1 158 ? 123.787 126.330 162.368 1.00 41.42  ? 184 GLY   A C   1 
ATOM   1273 O O   . GLY   A 1 158 ? 122.659 126.060 162.787 1.00 46.87  ? 184 GLY   A O   1 
ATOM   1274 N N   . LEU   A 1 159 ? 124.865 125.630 162.723 1.00 37.85  ? 185 LEU   A N   1 
ATOM   1275 C CA  . LEU   A 1 159 ? 124.748 124.536 163.678 1.00 37.19  ? 185 LEU   A CA  1 
ATOM   1276 C C   . LEU   A 1 159 ? 124.379 125.052 165.060 1.00 37.95  ? 185 LEU   A C   1 
ATOM   1277 O O   . LEU   A 1 159 ? 123.579 124.430 165.767 1.00 39.57  ? 185 LEU   A O   1 
ATOM   1278 C CB  . LEU   A 1 159 ? 126.054 123.744 163.731 1.00 36.90  ? 185 LEU   A CB  1 
ATOM   1279 C CG  . LEU   A 1 159 ? 126.503 123.061 162.438 1.00 38.98  ? 185 LEU   A CG  1 
ATOM   1280 C CD1 . LEU   A 1 159 ? 127.871 122.432 162.620 1.00 38.27  ? 185 LEU   A CD1 1 
ATOM   1281 C CD2 . LEU   A 1 159 ? 125.501 122.013 161.996 1.00 39.46  ? 185 LEU   A CD2 1 
ATOM   1282 N N   . LEU   A 1 160 ? 124.948 126.187 165.462 1.00 40.72  ? 186 LEU   A N   1 
ATOM   1283 C CA  . LEU   A 1 160 ? 124.655 126.759 166.772 1.00 41.56  ? 186 LEU   A CA  1 
ATOM   1284 C C   . LEU   A 1 160 ? 123.350 127.543 166.812 1.00 45.76  ? 186 LEU   A C   1 
ATOM   1285 O O   . LEU   A 1 160 ? 122.873 127.848 167.909 1.00 46.04  ? 186 LEU   A O   1 
ATOM   1286 C CB  . LEU   A 1 160 ? 125.797 127.677 167.217 1.00 41.60  ? 186 LEU   A CB  1 
ATOM   1287 C CG  . LEU   A 1 160 ? 126.996 127.041 167.922 1.00 49.97  ? 186 LEU   A CG  1 
ATOM   1288 C CD1 . LEU   A 1 160 ? 127.662 125.980 167.060 1.00 49.93  ? 186 LEU   A CD1 1 
ATOM   1289 C CD2 . LEU   A 1 160 ? 127.994 128.119 168.305 1.00 47.94  ? 186 LEU   A CD2 1 
ATOM   1290 N N   . ASN   A 1 161 ? 122.760 127.873 165.662 1.00 45.56  ? 187 ASN   A N   1 
ATOM   1291 C CA  . ASN   A 1 161 ? 121.540 128.672 165.605 1.00 40.24  ? 187 ASN   A CA  1 
ATOM   1292 C C   . ASN   A 1 161 ? 120.686 128.180 164.447 1.00 43.04  ? 187 ASN   A C   1 
ATOM   1293 O O   . ASN   A 1 161 ? 121.107 128.257 163.289 1.00 46.42  ? 187 ASN   A O   1 
ATOM   1294 C CB  . ASN   A 1 161 ? 121.867 130.157 165.443 1.00 39.07  ? 187 ASN   A CB  1 
ATOM   1295 C CG  . ASN   A 1 161 ? 120.645 131.038 165.558 1.00 46.91  ? 187 ASN   A CG  1 
ATOM   1296 O OD1 . ASN   A 1 161 ? 119.628 130.639 166.122 1.00 50.82  ? 187 ASN   A OD1 1 
ATOM   1297 N ND2 . ASN   A 1 161 ? 120.737 132.249 165.023 1.00 51.11  ? 187 ASN   A ND2 1 
ATOM   1298 N N   . ALA   A 1 162 ? 119.490 127.677 164.760 1.00 41.10  ? 188 ALA   A N   1 
ATOM   1299 C CA  . ALA   A 1 162 ? 118.654 127.043 163.744 1.00 38.81  ? 188 ALA   A CA  1 
ATOM   1300 C C   . ALA   A 1 162 ? 118.159 128.045 162.708 1.00 40.67  ? 188 ALA   A C   1 
ATOM   1301 O O   . ALA   A 1 162 ? 118.049 127.711 161.523 1.00 42.62  ? 188 ALA   A O   1 
ATOM   1302 C CB  . ALA   A 1 162 ? 117.473 126.340 164.408 1.00 41.83  ? 188 ALA   A CB  1 
ATOM   1303 N N   . HIS   A 1 163 ? 117.845 129.271 163.131 1.00 42.60  ? 189 HIS   A N   1 
ATOM   1304 C CA  . HIS   A 1 163 ? 117.246 130.248 162.226 1.00 42.66  ? 189 HIS   A CA  1 
ATOM   1305 C C   . HIS   A 1 163 ? 118.159 130.633 161.068 1.00 41.12  ? 189 HIS   A C   1 
ATOM   1306 O O   . HIS   A 1 163 ? 117.658 131.077 160.031 1.00 39.38  ? 189 HIS   A O   1 
ATOM   1307 C CB  . HIS   A 1 163 ? 116.856 131.506 163.000 1.00 44.18  ? 189 HIS   A CB  1 
ATOM   1308 C CG  . HIS   A 1 163 ? 115.738 131.293 163.971 1.00 52.52  ? 189 HIS   A CG  1 
ATOM   1309 N ND1 . HIS   A 1 163 ? 114.419 131.221 163.581 1.00 57.99  ? 189 HIS   A ND1 1 
ATOM   1310 C CD2 . HIS   A 1 163 ? 115.742 131.139 165.315 1.00 58.23  ? 189 HIS   A CD2 1 
ATOM   1311 C CE1 . HIS   A 1 163 ? 113.658 131.029 164.643 1.00 64.71  ? 189 HIS   A CE1 1 
ATOM   1312 N NE2 . HIS   A 1 163 ? 114.436 130.976 165.709 1.00 65.83  ? 189 HIS   A NE2 1 
ATOM   1313 N N   . ARG   A 1 164 ? 119.474 130.473 161.214 1.00 39.83  ? 190 ARG   A N   1 
ATOM   1314 C CA  . ARG   A 1 164 ? 120.444 130.831 160.186 1.00 40.86  ? 190 ARG   A CA  1 
ATOM   1315 C C   . ARG   A 1 164 ? 121.040 129.599 159.508 1.00 42.56  ? 190 ARG   A C   1 
ATOM   1316 O O   . ARG   A 1 164 ? 122.189 129.625 159.062 1.00 45.31  ? 190 ARG   A O   1 
ATOM   1317 C CB  . ARG   A 1 164 ? 121.556 131.692 160.784 1.00 42.35  ? 190 ARG   A CB  1 
ATOM   1318 C CG  . ARG   A 1 164 ? 121.102 133.048 161.268 1.00 45.70  ? 190 ARG   A CG  1 
ATOM   1319 C CD  . ARG   A 1 164 ? 122.253 133.819 161.878 1.00 49.44  ? 190 ARG   A CD  1 
ATOM   1320 N NE  . ARG   A 1 164 ? 121.876 135.181 162.245 1.00 58.30  ? 190 ARG   A NE  1 
ATOM   1321 C CZ  . ARG   A 1 164 ? 121.853 136.218 161.417 1.00 61.53  ? 190 ARG   A CZ  1 
ATOM   1322 N NH1 . ARG   A 1 164 ? 122.159 136.096 160.134 1.00 56.87  ? 190 ARG   A NH1 1 
ATOM   1323 N NH2 . ARG   A 1 164 ? 121.511 137.414 161.888 1.00 63.21  ? 190 ARG   A NH2 1 
ATOM   1324 N N   . ARG   A 1 165 ? 120.268 128.523 159.411 1.00 39.62  ? 191 ARG   A N   1 
ATOM   1325 C CA  . ARG   A 1 165 ? 120.735 127.245 158.878 1.00 39.54  ? 191 ARG   A CA  1 
ATOM   1326 C C   . ARG   A 1 165 ? 120.090 127.031 157.516 1.00 39.66  ? 191 ARG   A C   1 
ATOM   1327 O O   . ARG   A 1 165 ? 118.930 126.621 157.427 1.00 42.10  ? 191 ARG   A O   1 
ATOM   1328 C CB  . ARG   A 1 165 ? 120.400 126.110 159.837 1.00 39.25  ? 191 ARG   A CB  1 
ATOM   1329 C CG  . ARG   A 1 165 ? 120.926 124.759 159.412 1.00 39.90  ? 191 ARG   A CG  1 
ATOM   1330 C CD  . ARG   A 1 165 ? 121.173 123.881 160.620 1.00 42.26  ? 191 ARG   A CD  1 
ATOM   1331 N NE  . ARG   A 1 165 ? 121.356 122.481 160.260 1.00 48.42  ? 191 ARG   A NE  1 
ATOM   1332 C CZ  . ARG   A 1 165 ? 122.439 121.981 159.679 1.00 54.36  ? 191 ARG   A CZ  1 
ATOM   1333 N NH1 . ARG   A 1 165 ? 123.463 122.748 159.335 1.00 53.59  ? 191 ARG   A NH1 1 
ATOM   1334 N NH2 . ARG   A 1 165 ? 122.495 120.677 159.427 1.00 55.53  ? 191 ARG   A NH2 1 
ATOM   1335 N N   . ASN   A 1 166 ? 120.855 127.293 156.459 1.00 37.90  ? 192 ASN   A N   1 
ATOM   1336 C CA  . ASN   A 1 166 ? 120.398 127.107 155.086 1.00 35.16  ? 192 ASN   A CA  1 
ATOM   1337 C C   . ASN   A 1 166 ? 119.149 127.946 154.817 1.00 38.62  ? 192 ASN   A C   1 
ATOM   1338 O O   . ASN   A 1 166 ? 118.069 127.431 154.523 1.00 40.76  ? 192 ASN   A O   1 
ATOM   1339 C CB  . ASN   A 1 166 ? 120.146 125.624 154.803 1.00 33.93  ? 192 ASN   A CB  1 
ATOM   1340 C CG  . ASN   A 1 166 ? 120.046 125.323 153.326 1.00 40.86  ? 192 ASN   A CG  1 
ATOM   1341 O OD1 . ASN   A 1 166 ? 119.379 126.033 152.579 1.00 47.17  ? 192 ASN   A OD1 1 
ATOM   1342 N ND2 . ASN   A 1 166 ? 120.716 124.266 152.894 1.00 44.72  ? 192 ASN   A ND2 1 
ATOM   1343 N N   . ALA   A 1 167 ? 119.319 129.259 154.933 1.00 37.13  ? 193 ALA   A N   1 
ATOM   1344 C CA  . ALA   A 1 167 ? 118.255 130.232 154.736 1.00 34.62  ? 193 ALA   A CA  1 
ATOM   1345 C C   . ALA   A 1 167 ? 118.559 131.112 153.529 1.00 33.70  ? 193 ALA   A C   1 
ATOM   1346 O O   . ALA   A 1 167 ? 119.662 131.103 152.980 1.00 39.38  ? 193 ALA   A O   1 
ATOM   1347 C CB  . ALA   A 1 167 ? 118.071 131.091 155.990 1.00 35.64  ? 193 ALA   A CB  1 
ATOM   1348 N N   . HIS   A 1 168 ? 117.552 131.877 153.121 1.00 32.01  ? 194 HIS   A N   1 
ATOM   1349 C CA  . HIS   A 1 168 ? 117.674 132.760 151.974 1.00 32.43  ? 194 HIS   A CA  1 
ATOM   1350 C C   . HIS   A 1 168 ? 118.501 133.992 152.322 1.00 33.71  ? 194 HIS   A C   1 
ATOM   1351 O O   . HIS   A 1 168 ? 118.651 134.364 153.488 1.00 38.51  ? 194 HIS   A O   1 
ATOM   1352 C CB  . HIS   A 1 168 ? 116.295 133.204 151.482 1.00 32.97  ? 194 HIS   A CB  1 
ATOM   1353 C CG  . HIS   A 1 168 ? 115.612 132.217 150.587 1.00 32.49  ? 194 HIS   A CG  1 
ATOM   1354 N ND1 . HIS   A 1 168 ? 114.276 131.907 150.713 1.00 31.96  ? 194 HIS   A ND1 1 
ATOM   1355 C CD2 . HIS   A 1 168 ? 116.065 131.500 149.533 1.00 33.50  ? 194 HIS   A CD2 1 
ATOM   1356 C CE1 . HIS   A 1 168 ? 113.941 131.026 149.789 1.00 29.78  ? 194 HIS   A CE1 1 
ATOM   1357 N NE2 . HIS   A 1 168 ? 115.007 130.765 149.057 1.00 32.11  ? 194 HIS   A NE2 1 
ATOM   1358 N N   . VAL   A 1 169 ? 119.037 134.624 151.281 1.00 30.66  ? 195 VAL   A N   1 
ATOM   1359 C CA  . VAL   A 1 169 ? 119.788 135.872 151.398 1.00 30.15  ? 195 VAL   A CA  1 
ATOM   1360 C C   . VAL   A 1 169 ? 119.245 136.846 150.356 1.00 36.69  ? 195 VAL   A C   1 
ATOM   1361 O O   . VAL   A 1 169 ? 118.753 136.399 149.309 1.00 42.76  ? 195 VAL   A O   1 
ATOM   1362 C CB  . VAL   A 1 169 ? 121.297 135.646 151.213 1.00 31.55  ? 195 VAL   A CB  1 
ATOM   1363 C CG1 . VAL   A 1 169 ? 121.823 134.654 152.238 1.00 36.06  ? 195 VAL   A CG1 1 
ATOM   1364 C CG2 . VAL   A 1 169 ? 121.612 135.193 149.793 1.00 33.51  ? 195 VAL   A CG2 1 
ATOM   1365 N N   . PRO   A 1 170 ? 119.300 138.159 150.573 1.00 33.36  ? 196 PRO   A N   1 
ATOM   1366 C CA  . PRO   A 1 170 ? 118.820 139.089 149.547 1.00 29.01  ? 196 PRO   A CA  1 
ATOM   1367 C C   . PRO   A 1 170 ? 119.752 139.125 148.348 1.00 32.15  ? 196 PRO   A C   1 
ATOM   1368 O O   . PRO   A 1 170 ? 120.889 138.654 148.383 1.00 38.83  ? 196 PRO   A O   1 
ATOM   1369 C CB  . PRO   A 1 170 ? 118.776 140.435 150.271 1.00 34.09  ? 196 PRO   A CB  1 
ATOM   1370 C CG  . PRO   A 1 170 ? 119.714 140.295 151.388 1.00 36.72  ? 196 PRO   A CG  1 
ATOM   1371 C CD  . PRO   A 1 170 ? 119.654 138.871 151.812 1.00 36.87  ? 196 PRO   A CD  1 
ATOM   1372 N N   . LEU   A 1 171 ? 119.243 139.704 147.261 1.00 32.22  ? 197 LEU   A N   1 
ATOM   1373 C CA  . LEU   A 1 171 ? 119.941 139.635 145.984 1.00 32.34  ? 197 LEU   A CA  1 
ATOM   1374 C C   . LEU   A 1 171 ? 121.103 140.612 145.885 1.00 35.48  ? 197 LEU   A C   1 
ATOM   1375 O O   . LEU   A 1 171 ? 122.050 140.351 145.136 1.00 42.87  ? 197 LEU   A O   1 
ATOM   1376 C CB  . LEU   A 1 171 ? 118.959 139.885 144.839 1.00 34.51  ? 197 LEU   A CB  1 
ATOM   1377 C CG  . LEU   A 1 171 ? 119.520 139.883 143.413 1.00 38.13  ? 197 LEU   A CG  1 
ATOM   1378 C CD1 . LEU   A 1 171 ? 120.252 138.587 143.107 1.00 37.21  ? 197 LEU   A CD1 1 
ATOM   1379 C CD2 . LEU   A 1 171 ? 118.411 140.103 142.408 1.00 39.91  ? 197 LEU   A CD2 1 
ATOM   1380 N N   . TRP   A 1 172 ? 121.068 141.735 146.606 1.00 33.62  ? 198 TRP   A N   1 
ATOM   1381 C CA  . TRP   A 1 172 ? 122.144 142.706 146.449 1.00 36.56  ? 198 TRP   A CA  1 
ATOM   1382 C C   . TRP   A 1 172 ? 123.467 142.198 147.006 1.00 40.45  ? 198 TRP   A C   1 
ATOM   1383 O O   . TRP   A 1 172 ? 124.519 142.752 146.664 1.00 44.36  ? 198 TRP   A O   1 
ATOM   1384 C CB  . TRP   A 1 172 ? 121.771 144.048 147.090 1.00 34.92  ? 198 TRP   A CB  1 
ATOM   1385 C CG  . TRP   A 1 172 ? 121.635 144.073 148.578 1.00 30.27  ? 198 TRP   A CG  1 
ATOM   1386 C CD1 . TRP   A 1 172 ? 120.482 144.013 149.291 1.00 32.17  ? 198 TRP   A CD1 1 
ATOM   1387 C CD2 . TRP   A 1 172 ? 122.690 144.207 149.535 1.00 35.45  ? 198 TRP   A CD2 1 
ATOM   1388 N NE1 . TRP   A 1 172 ? 120.747 144.085 150.632 1.00 35.15  ? 198 TRP   A NE1 1 
ATOM   1389 C CE2 . TRP   A 1 172 ? 122.098 144.205 150.810 1.00 34.68  ? 198 TRP   A CE2 1 
ATOM   1390 C CE3 . TRP   A 1 172 ? 124.081 144.320 149.439 1.00 42.48  ? 198 TRP   A CE3 1 
ATOM   1391 C CZ2 . TRP   A 1 172 ? 122.844 144.308 151.978 1.00 35.28  ? 198 TRP   A CZ2 1 
ATOM   1392 C CZ3 . TRP   A 1 172 ? 124.818 144.419 150.601 1.00 39.76  ? 198 TRP   A CZ3 1 
ATOM   1393 C CH2 . TRP   A 1 172 ? 124.199 144.412 151.852 1.00 35.98  ? 198 TRP   A CH2 1 
ATOM   1394 N N   . ASN   A 1 173 ? 123.441 141.152 147.838 1.00 36.34  ? 199 ASN   A N   1 
ATOM   1395 C CA  . ASN   A 1 173 ? 124.680 140.544 148.307 1.00 33.81  ? 199 ASN   A CA  1 
ATOM   1396 C C   . ASN   A 1 173 ? 125.516 140.043 147.140 1.00 40.72  ? 199 ASN   A C   1 
ATOM   1397 O O   . ASN   A 1 173 ? 126.739 140.228 147.117 1.00 49.16  ? 199 ASN   A O   1 
ATOM   1398 C CB  . ASN   A 1 173 ? 124.368 139.402 149.272 1.00 33.00  ? 199 ASN   A CB  1 
ATOM   1399 C CG  . ASN   A 1 173 ? 123.836 139.890 150.601 1.00 38.06  ? 199 ASN   A CG  1 
ATOM   1400 O OD1 . ASN   A 1 173 ? 124.205 140.961 151.076 1.00 43.58  ? 199 ASN   A OD1 1 
ATOM   1401 N ND2 . ASN   A 1 173 ? 122.965 139.106 151.210 1.00 37.50  ? 199 ASN   A ND2 1 
ATOM   1402 N N   . TYR   A 1 174 ? 124.879 139.404 146.161 1.00 36.90  ? 200 TYR   A N   1 
ATOM   1403 C CA  . TYR   A 1 174 ? 125.592 138.998 144.957 1.00 39.04  ? 200 TYR   A CA  1 
ATOM   1404 C C   . TYR   A 1 174 ? 125.838 140.172 144.020 1.00 43.30  ? 200 TYR   A C   1 
ATOM   1405 O O   . TYR   A 1 174 ? 126.873 140.210 143.342 1.00 48.49  ? 200 TYR   A O   1 
ATOM   1406 C CB  . TYR   A 1 174 ? 124.809 137.911 144.223 1.00 37.20  ? 200 TYR   A CB  1 
ATOM   1407 C CG  . TYR   A 1 174 ? 124.629 136.640 145.013 1.00 33.83  ? 200 TYR   A CG  1 
ATOM   1408 C CD1 . TYR   A 1 174 ? 125.638 135.701 145.085 1.00 35.45  ? 200 TYR   A CD1 1 
ATOM   1409 C CD2 . TYR   A 1 174 ? 123.444 136.377 145.672 1.00 33.34  ? 200 TYR   A CD2 1 
ATOM   1410 C CE1 . TYR   A 1 174 ? 125.477 134.542 145.798 1.00 37.95  ? 200 TYR   A CE1 1 
ATOM   1411 C CE2 . TYR   A 1 174 ? 123.275 135.223 146.389 1.00 33.84  ? 200 TYR   A CE2 1 
ATOM   1412 C CZ  . TYR   A 1 174 ? 124.294 134.307 146.448 1.00 37.92  ? 200 TYR   A CZ  1 
ATOM   1413 O OH  . TYR   A 1 174 ? 124.131 133.146 147.164 1.00 41.29  ? 200 TYR   A OH  1 
ATOM   1414 N N   . ALA   A 1 175 ? 124.901 141.121 143.961 1.00 39.22  ? 201 ALA   A N   1 
ATOM   1415 C CA  . ALA   A 1 175 ? 125.019 142.231 143.021 1.00 38.90  ? 201 ALA   A CA  1 
ATOM   1416 C C   . ALA   A 1 175 ? 126.242 143.084 143.317 1.00 43.68  ? 201 ALA   A C   1 
ATOM   1417 O O   . ALA   A 1 175 ? 126.952 143.499 142.394 1.00 47.41  ? 201 ALA   A O   1 
ATOM   1418 C CB  . ALA   A 1 175 ? 123.757 143.089 143.057 1.00 37.87  ? 201 ALA   A CB  1 
ATOM   1419 N N   . VAL   A 1 176 ? 126.504 143.363 144.595 1.00 43.07  ? 202 VAL   A N   1 
ATOM   1420 C CA  . VAL   A 1 176 ? 127.634 144.219 144.947 1.00 41.63  ? 202 VAL   A CA  1 
ATOM   1421 C C   . VAL   A 1 176 ? 128.948 143.560 144.543 1.00 44.57  ? 202 VAL   A C   1 
ATOM   1422 O O   . VAL   A 1 176 ? 129.832 144.207 143.968 1.00 50.27  ? 202 VAL   A O   1 
ATOM   1423 C CB  . VAL   A 1 176 ? 127.604 144.555 146.450 1.00 38.32  ? 202 VAL   A CB  1 
ATOM   1424 C CG1 . VAL   A 1 176 ? 128.874 145.268 146.865 1.00 42.25  ? 202 VAL   A CG1 1 
ATOM   1425 C CG2 . VAL   A 1 176 ? 126.406 145.414 146.786 1.00 40.80  ? 202 VAL   A CG2 1 
ATOM   1426 N N   . LEU   A 1 177 ? 129.096 142.266 144.829 1.00 42.36  ? 203 LEU   A N   1 
ATOM   1427 C CA  . LEU   A 1 177 ? 130.323 141.563 144.468 1.00 44.53  ? 203 LEU   A CA  1 
ATOM   1428 C C   . LEU   A 1 177 ? 130.497 141.479 142.955 1.00 47.08  ? 203 LEU   A C   1 
ATOM   1429 O O   . LEU   A 1 177 ? 131.607 141.686 142.438 1.00 52.10  ? 203 LEU   A O   1 
ATOM   1430 C CB  . LEU   A 1 177 ? 130.323 140.167 145.087 1.00 46.55  ? 203 LEU   A CB  1 
ATOM   1431 C CG  . LEU   A 1 177 ? 130.396 140.117 146.615 1.00 45.96  ? 203 LEU   A CG  1 
ATOM   1432 C CD1 . LEU   A 1 177 ? 129.896 138.792 147.157 1.00 44.94  ? 203 LEU   A CD1 1 
ATOM   1433 C CD2 . LEU   A 1 177 ? 131.816 140.363 147.090 1.00 46.98  ? 203 LEU   A CD2 1 
ATOM   1434 N N   . ARG   A 1 178 ? 129.419 141.170 142.228 1.00 42.86  ? 204 ARG   A N   1 
ATOM   1435 C CA  . ARG   A 1 178 ? 129.510 141.115 140.773 1.00 44.72  ? 204 ARG   A CA  1 
ATOM   1436 C C   . ARG   A 1 178 ? 129.907 142.469 140.203 1.00 47.16  ? 204 ARG   A C   1 
ATOM   1437 O O   . ARG   A 1 178 ? 130.755 142.552 139.304 1.00 49.31  ? 204 ARG   A O   1 
ATOM   1438 C CB  . ARG   A 1 178 ? 128.179 140.661 140.179 1.00 43.87  ? 204 ARG   A CB  1 
ATOM   1439 C CG  . ARG   A 1 178 ? 127.823 139.212 140.441 1.00 41.84  ? 204 ARG   A CG  1 
ATOM   1440 C CD  . ARG   A 1 178 ? 126.438 138.905 139.900 1.00 43.49  ? 204 ARG   A CD  1 
ATOM   1441 N NE  . ARG   A 1 178 ? 125.978 137.568 140.251 1.00 43.69  ? 204 ARG   A NE  1 
ATOM   1442 C CZ  . ARG   A 1 178 ? 124.843 137.025 139.832 1.00 46.63  ? 204 ARG   A CZ  1 
ATOM   1443 N NH1 . ARG   A 1 178 ? 124.012 137.677 139.034 1.00 47.32  ? 204 ARG   A NH1 1 
ATOM   1444 N NH2 . ARG   A 1 178 ? 124.535 135.791 140.219 1.00 46.32  ? 204 ARG   A NH2 1 
ATOM   1445 N N   . GLY   A 1 179 ? 129.313 143.543 140.724 1.00 46.16  ? 205 GLY   A N   1 
ATOM   1446 C CA  . GLY   A 1 179 ? 129.682 144.871 140.273 1.00 45.58  ? 205 GLY   A CA  1 
ATOM   1447 C C   . GLY   A 1 179 ? 131.126 145.208 140.579 1.00 45.06  ? 205 GLY   A C   1 
ATOM   1448 O O   . GLY   A 1 179 ? 131.804 145.845 139.774 1.00 49.52  ? 205 GLY   A O   1 
ATOM   1449 N N   . GLN   A 1 180 ? 131.615 144.792 141.749 1.00 41.89  ? 206 GLN   A N   1 
ATOM   1450 C CA  . GLN   A 1 180 ? 133.006 145.059 142.101 1.00 44.79  ? 206 GLN   A CA  1 
ATOM   1451 C C   . GLN   A 1 180 ? 133.958 144.369 141.132 1.00 45.71  ? 206 GLN   A C   1 
ATOM   1452 O O   . GLN   A 1 180 ? 134.924 144.980 140.654 1.00 49.55  ? 206 GLN   A O   1 
ATOM   1453 C CB  . GLN   A 1 180 ? 133.273 144.606 143.537 1.00 47.93  ? 206 GLN   A CB  1 
ATOM   1454 C CG  . GLN   A 1 180 ? 134.654 144.944 144.079 1.00 51.14  ? 206 GLN   A CG  1 
ATOM   1455 C CD  . GLN   A 1 180 ? 134.877 146.429 144.220 1.00 55.76  ? 206 GLN   A CD  1 
ATOM   1456 O OE1 . GLN   A 1 180 ? 133.963 147.173 144.573 1.00 53.97  ? 206 GLN   A OE1 1 
ATOM   1457 N NE2 . GLN   A 1 180 ? 136.094 146.874 143.937 1.00 57.53  ? 206 GLN   A NE2 1 
ATOM   1458 N N   . ILE   A 1 181 ? 133.694 143.101 140.815 1.00 42.47  ? 207 ILE   A N   1 
ATOM   1459 C CA  . ILE   A 1 181 ? 134.581 142.383 139.901 1.00 44.27  ? 207 ILE   A CA  1 
ATOM   1460 C C   . ILE   A 1 181 ? 134.503 142.981 138.499 1.00 43.93  ? 207 ILE   A C   1 
ATOM   1461 O O   . ILE   A 1 181 ? 135.525 143.114 137.804 1.00 45.92  ? 207 ILE   A O   1 
ATOM   1462 C CB  . ILE   A 1 181 ? 134.252 140.879 139.902 1.00 45.94  ? 207 ILE   A CB  1 
ATOM   1463 C CG1 . ILE   A 1 181 ? 134.414 140.273 141.307 1.00 46.09  ? 207 ILE   A CG1 1 
ATOM   1464 C CG2 . ILE   A 1 181 ? 135.120 140.147 138.898 1.00 48.25  ? 207 ILE   A CG2 1 
ATOM   1465 C CD1 . ILE   A 1 181 ? 135.808 140.369 141.919 1.00 47.14  ? 207 ILE   A CD1 1 
ATOM   1466 N N   . PHE   A 1 182 ? 133.296 143.345 138.057 1.00 43.50  ? 208 PHE   A N   1 
ATOM   1467 C CA  . PHE   A 1 182 ? 133.144 143.990 136.757 1.00 40.85  ? 208 PHE   A CA  1 
ATOM   1468 C C   . PHE   A 1 182 ? 133.903 145.305 136.709 1.00 42.38  ? 208 PHE   A C   1 
ATOM   1469 O O   . PHE   A 1 182 ? 134.532 145.628 135.695 1.00 47.96  ? 208 PHE   A O   1 
ATOM   1470 C CB  . PHE   A 1 182 ? 131.664 144.221 136.462 1.00 43.93  ? 208 PHE   A CB  1 
ATOM   1471 C CG  . PHE   A 1 182 ? 131.397 144.823 135.111 1.00 46.53  ? 208 PHE   A CG  1 
ATOM   1472 C CD1 . PHE   A 1 182 ? 131.249 144.017 134.002 1.00 50.55  ? 208 PHE   A CD1 1 
ATOM   1473 C CD2 . PHE   A 1 182 ? 131.275 146.192 134.954 1.00 47.33  ? 208 PHE   A CD2 1 
ATOM   1474 C CE1 . PHE   A 1 182 ? 130.999 144.561 132.762 1.00 52.04  ? 208 PHE   A CE1 1 
ATOM   1475 C CE2 . PHE   A 1 182 ? 131.029 146.741 133.718 1.00 47.76  ? 208 PHE   A CE2 1 
ATOM   1476 C CZ  . PHE   A 1 182 ? 130.887 145.927 132.621 1.00 50.75  ? 208 PHE   A CZ  1 
ATOM   1477 N N   . ILE   A 1 183 ? 133.842 146.086 137.788 1.00 43.27  ? 209 ILE   A N   1 
ATOM   1478 C CA  . ILE   A 1 183 ? 134.561 147.352 137.838 1.00 41.79  ? 209 ILE   A CA  1 
ATOM   1479 C C   . ILE   A 1 183 ? 136.055 147.104 137.742 1.00 42.43  ? 209 ILE   A C   1 
ATOM   1480 O O   . ILE   A 1 183 ? 136.766 147.811 137.021 1.00 48.95  ? 209 ILE   A O   1 
ATOM   1481 C CB  . ILE   A 1 183 ? 134.190 148.133 139.113 1.00 43.21  ? 209 ILE   A CB  1 
ATOM   1482 C CG1 . ILE   A 1 183 ? 132.769 148.685 138.996 1.00 45.09  ? 209 ILE   A CG1 1 
ATOM   1483 C CG2 . ILE   A 1 183 ? 135.170 149.276 139.357 1.00 44.22  ? 209 ILE   A CG2 1 
ATOM   1484 C CD1 . ILE   A 1 183 ? 132.132 149.052 140.319 1.00 46.35  ? 209 ILE   A CD1 1 
ATOM   1485 N N   . VAL   A 1 184 ? 136.551 146.086 138.450 1.00 42.77  ? 210 VAL   A N   1 
ATOM   1486 C CA  . VAL   A 1 184 ? 137.977 145.773 138.396 1.00 44.19  ? 210 VAL   A CA  1 
ATOM   1487 C C   . VAL   A 1 184 ? 138.398 145.485 136.961 1.00 44.01  ? 210 VAL   A C   1 
ATOM   1488 O O   . VAL   A 1 184 ? 139.306 146.132 136.421 1.00 45.38  ? 210 VAL   A O   1 
ATOM   1489 C CB  . VAL   A 1 184 ? 138.301 144.591 139.328 1.00 42.92  ? 210 VAL   A CB  1 
ATOM   1490 C CG1 . VAL   A 1 184 ? 139.703 144.070 139.074 1.00 45.70  ? 210 VAL   A CG1 1 
ATOM   1491 C CG2 . VAL   A 1 184 ? 138.159 145.001 140.781 1.00 45.37  ? 210 VAL   A CG2 1 
ATOM   1492 N N   . TYR   A 1 185 ? 137.687 144.569 136.297 1.00 45.11  ? 211 TYR   A N   1 
ATOM   1493 C CA  . TYR   A 1 185 ? 138.063 144.190 134.935 1.00 42.78  ? 211 TYR   A CA  1 
ATOM   1494 C C   . TYR   A 1 185 ? 137.956 145.371 133.975 1.00 45.50  ? 211 TYR   A C   1 
ATOM   1495 O O   . TYR   A 1 185 ? 138.891 145.658 133.218 1.00 50.91  ? 211 TYR   A O   1 
ATOM   1496 C CB  . TYR   A 1 185 ? 137.189 143.038 134.445 1.00 43.58  ? 211 TYR   A CB  1 
ATOM   1497 C CG  . TYR   A 1 185 ? 137.592 141.674 134.951 1.00 47.59  ? 211 TYR   A CG  1 
ATOM   1498 C CD1 . TYR   A 1 185 ? 138.755 141.066 134.513 1.00 50.52  ? 211 TYR   A CD1 1 
ATOM   1499 C CD2 . TYR   A 1 185 ? 136.792 140.981 135.841 1.00 48.57  ? 211 TYR   A CD2 1 
ATOM   1500 C CE1 . TYR   A 1 185 ? 139.118 139.820 134.963 1.00 51.12  ? 211 TYR   A CE1 1 
ATOM   1501 C CE2 . TYR   A 1 185 ? 137.148 139.734 136.294 1.00 50.17  ? 211 TYR   A CE2 1 
ATOM   1502 C CZ  . TYR   A 1 185 ? 138.309 139.159 135.854 1.00 51.08  ? 211 TYR   A CZ  1 
ATOM   1503 O OH  . TYR   A 1 185 ? 138.660 137.912 136.310 1.00 54.27  ? 211 TYR   A OH  1 
ATOM   1504 N N   . PHE   A 1 186 ? 136.827 146.081 134.002 1.00 43.22  ? 212 PHE   A N   1 
ATOM   1505 C CA  . PHE   A 1 186 ? 136.584 147.127 133.014 1.00 41.17  ? 212 PHE   A CA  1 
ATOM   1506 C C   . PHE   A 1 186 ? 137.505 148.322 133.217 1.00 43.28  ? 212 PHE   A C   1 
ATOM   1507 O O   . PHE   A 1 186 ? 138.033 148.871 132.243 1.00 47.48  ? 212 PHE   A O   1 
ATOM   1508 C CB  . PHE   A 1 186 ? 135.124 147.565 133.075 1.00 45.31  ? 212 PHE   A CB  1 
ATOM   1509 C CG  . PHE   A 1 186 ? 134.696 148.420 131.922 1.00 47.61  ? 212 PHE   A CG  1 
ATOM   1510 C CD1 . PHE   A 1 186 ? 134.571 147.885 130.656 1.00 49.65  ? 212 PHE   A CD1 1 
ATOM   1511 C CD2 . PHE   A 1 186 ? 134.392 149.754 132.108 1.00 47.59  ? 212 PHE   A CD2 1 
ATOM   1512 C CE1 . PHE   A 1 186 ? 134.169 148.666 129.599 1.00 47.64  ? 212 PHE   A CE1 1 
ATOM   1513 C CE2 . PHE   A 1 186 ? 133.988 150.537 131.054 1.00 47.67  ? 212 PHE   A CE2 1 
ATOM   1514 C CZ  . PHE   A 1 186 ? 133.877 149.992 129.799 1.00 47.82  ? 212 PHE   A CZ  1 
ATOM   1515 N N   . ILE   A 1 187 ? 137.692 148.767 134.460 1.00 42.42  ? 213 ILE   A N   1 
ATOM   1516 C CA  . ILE   A 1 187 ? 138.555 149.915 134.695 1.00 39.45  ? 213 ILE   A CA  1 
ATOM   1517 C C   . ILE   A 1 187 ? 140.007 149.550 134.424 1.00 39.87  ? 213 ILE   A C   1 
ATOM   1518 O O   . ILE   A 1 187 ? 140.782 150.380 133.936 1.00 44.21  ? 213 ILE   A O   1 
ATOM   1519 C CB  . ILE   A 1 187 ? 138.356 150.466 136.119 1.00 40.88  ? 213 ILE   A CB  1 
ATOM   1520 C CG1 . ILE   A 1 187 ? 136.896 150.886 136.359 1.00 43.52  ? 213 ILE   A CG1 1 
ATOM   1521 C CG2 . ILE   A 1 187 ? 139.297 151.632 136.370 1.00 43.70  ? 213 ILE   A CG2 1 
ATOM   1522 C CD1 . ILE   A 1 187 ? 136.354 151.968 135.438 1.00 43.95  ? 213 ILE   A CD1 1 
ATOM   1523 N N   . ALA   A 1 188 ? 140.409 148.310 134.721 1.00 41.98  ? 214 ALA   A N   1 
ATOM   1524 C CA  . ALA   A 1 188 ? 141.750 147.885 134.343 1.00 43.95  ? 214 ALA   A CA  1 
ATOM   1525 C C   . ALA   A 1 188 ? 141.918 147.901 132.831 1.00 45.83  ? 214 ALA   A C   1 
ATOM   1526 O O   . ALA   A 1 188 ? 142.966 148.314 132.320 1.00 49.78  ? 214 ALA   A O   1 
ATOM   1527 C CB  . ALA   A 1 188 ? 142.038 146.493 134.900 1.00 46.14  ? 214 ALA   A CB  1 
ATOM   1528 N N   . GLY   A 1 189 ? 140.898 147.456 132.096 1.00 43.53  ? 215 GLY   A N   1 
ATOM   1529 C CA  . GLY   A 1 189 ? 140.991 147.474 130.645 1.00 42.75  ? 215 GLY   A CA  1 
ATOM   1530 C C   . GLY   A 1 189 ? 141.073 148.879 130.079 1.00 44.12  ? 215 GLY   A C   1 
ATOM   1531 O O   . GLY   A 1 189 ? 141.926 149.174 129.239 1.00 47.98  ? 215 GLY   A O   1 
ATOM   1532 N N   . VAL   A 1 190 ? 140.195 149.771 130.540 1.00 41.59  ? 216 VAL   A N   1 
ATOM   1533 C CA  . VAL   A 1 190 ? 140.160 151.119 129.980 1.00 39.01  ? 216 VAL   A CA  1 
ATOM   1534 C C   . VAL   A 1 190 ? 141.408 151.900 130.381 1.00 43.06  ? 216 VAL   A C   1 
ATOM   1535 O O   . VAL   A 1 190 ? 141.911 152.724 129.610 1.00 47.69  ? 216 VAL   A O   1 
ATOM   1536 C CB  . VAL   A 1 190 ? 138.864 151.846 130.386 1.00 38.66  ? 216 VAL   A CB  1 
ATOM   1537 C CG1 . VAL   A 1 190 ? 138.921 152.321 131.814 1.00 41.59  ? 216 VAL   A CG1 1 
ATOM   1538 C CG2 . VAL   A 1 190 ? 138.599 153.011 129.452 1.00 41.16  ? 216 VAL   A CG2 1 
ATOM   1539 N N   . LYS   A 1 191 ? 141.922 151.667 131.592 1.00 45.24  ? 217 LYS   A N   1 
ATOM   1540 C CA  . LYS   A 1 191 ? 143.178 152.295 131.989 1.00 42.29  ? 217 LYS   A CA  1 
ATOM   1541 C C   . LYS   A 1 191 ? 144.335 151.826 131.121 1.00 42.61  ? 217 LYS   A C   1 
ATOM   1542 O O   . LYS   A 1 191 ? 145.321 152.554 130.961 1.00 48.12  ? 217 LYS   A O   1 
ATOM   1543 C CB  . LYS   A 1 191 ? 143.472 152.001 133.458 1.00 43.78  ? 217 LYS   A CB  1 
ATOM   1544 C CG  . LYS   A 1 191 ? 142.623 152.788 134.439 1.00 45.09  ? 217 LYS   A CG  1 
ATOM   1545 C CD  . LYS   A 1 191 ? 143.104 154.215 134.577 1.00 47.69  ? 217 LYS   A CD  1 
ATOM   1546 C CE  . LYS   A 1 191 ? 142.371 154.931 135.692 1.00 51.27  ? 217 LYS   A CE  1 
ATOM   1547 N NZ  . LYS   A 1 191 ? 142.892 156.305 135.912 1.00 52.59  ? 217 LYS   A NZ  1 
ATOM   1548 N N   . LYS   A 1 192 ? 144.240 150.624 130.560 1.00 41.72  ? 218 LYS   A N   1 
ATOM   1549 C CA  . LYS   A 1 192 ? 145.272 150.097 129.681 1.00 43.14  ? 218 LYS   A CA  1 
ATOM   1550 C C   . LYS   A 1 192 ? 145.141 150.591 128.248 1.00 46.70  ? 218 LYS   A C   1 
ATOM   1551 O O   . LYS   A 1 192 ? 145.908 150.147 127.389 1.00 51.00  ? 218 LYS   A O   1 
ATOM   1552 C CB  . LYS   A 1 192 ? 145.249 148.569 129.713 1.00 47.89  ? 218 LYS   A CB  1 
ATOM   1553 C CG  . LYS   A 1 192 ? 145.884 147.987 130.963 1.00 51.87  ? 218 LYS   A CG  1 
ATOM   1554 C CD  . LYS   A 1 192 ? 145.801 146.475 130.984 1.00 53.24  ? 218 LYS   A CD  1 
ATOM   1555 C CE  . LYS   A 1 192 ? 146.513 145.897 132.190 1.00 53.40  ? 218 LYS   A CE  1 
ATOM   1556 N NZ  . LYS   A 1 192 ? 145.893 146.327 133.471 1.00 53.36  ? 218 LYS   A NZ  1 
ATOM   1557 N N   . LEU   A 1 193 ? 144.202 151.497 127.965 1.00 47.51  ? 219 LEU   A N   1 
ATOM   1558 C CA  . LEU   A 1 193 ? 144.139 152.181 126.673 1.00 48.85  ? 219 LEU   A CA  1 
ATOM   1559 C C   . LEU   A 1 193 ? 145.062 153.400 126.680 1.00 47.26  ? 219 LEU   A C   1 
ATOM   1560 O O   . LEU   A 1 193 ? 144.652 154.538 126.461 1.00 48.17  ? 219 LEU   A O   1 
ATOM   1561 C CB  . LEU   A 1 193 ? 142.701 152.576 126.349 1.00 47.70  ? 219 LEU   A CB  1 
ATOM   1562 C CG  . LEU   A 1 193 ? 141.736 151.471 125.917 1.00 47.89  ? 219 LEU   A CG  1 
ATOM   1563 C CD1 . LEU   A 1 193 ? 140.312 151.985 125.946 1.00 48.59  ? 219 LEU   A CD1 1 
ATOM   1564 C CD2 . LEU   A 1 193 ? 142.077 150.964 124.528 1.00 51.36  ? 219 LEU   A CD2 1 
ATOM   1565 N N   . ASP   A 1 194 ? 146.335 153.131 126.951 1.00 46.98  ? 220 ASP   A N   1 
ATOM   1566 C CA  . ASP   A 1 194 ? 147.381 154.136 127.044 1.00 48.93  ? 220 ASP   A CA  1 
ATOM   1567 C C   . ASP   A 1 194 ? 148.371 153.931 125.906 1.00 50.77  ? 220 ASP   A C   1 
ATOM   1568 O O   . ASP   A 1 194 ? 148.498 152.834 125.357 1.00 52.62  ? 220 ASP   A O   1 
ATOM   1569 C CB  . ASP   A 1 194 ? 148.095 154.051 128.398 1.00 51.31  ? 220 ASP   A CB  1 
ATOM   1570 C CG  . ASP   A 1 194 ? 148.972 155.255 128.679 1.00 60.02  ? 220 ASP   A CG  1 
ATOM   1571 O OD1 . ASP   A 1 194 ? 149.073 156.145 127.808 1.00 62.12  ? 220 ASP   A OD1 1 
ATOM   1572 O OD2 . ASP   A 1 194 ? 149.563 155.311 129.777 1.00 62.54  ? 220 ASP   A OD2 1 
ATOM   1573 N N   . ALA   A 1 195 ? 149.076 155.005 125.556 1.00 48.37  ? 221 ALA   A N   1 
ATOM   1574 C CA  . ALA   A 1 195 ? 149.985 154.948 124.420 1.00 49.34  ? 221 ALA   A CA  1 
ATOM   1575 C C   . ALA   A 1 195 ? 151.142 153.984 124.646 1.00 52.72  ? 221 ALA   A C   1 
ATOM   1576 O O   . ALA   A 1 195 ? 151.691 153.463 123.670 1.00 57.02  ? 221 ALA   A O   1 
ATOM   1577 C CB  . ALA   A 1 195 ? 150.527 156.344 124.116 1.00 54.05  ? 221 ALA   A CB  1 
ATOM   1578 N N   . ASP   A 1 196 ? 151.517 153.730 125.897 1.00 47.85  ? 222 ASP   A N   1 
ATOM   1579 C CA  . ASP   A 1 196 ? 152.631 152.847 126.207 1.00 47.75  ? 222 ASP   A CA  1 
ATOM   1580 C C   . ASP   A 1 196 ? 152.220 151.392 126.392 1.00 49.44  ? 222 ASP   A C   1 
ATOM   1581 O O   . ASP   A 1 196 ? 153.100 150.539 126.546 1.00 53.90  ? 222 ASP   A O   1 
ATOM   1582 C CB  . ASP   A 1 196 ? 153.342 153.326 127.476 1.00 52.38  ? 222 ASP   A CB  1 
ATOM   1583 C CG  . ASP   A 1 196 ? 154.043 154.655 127.284 1.00 60.30  ? 222 ASP   A CG  1 
ATOM   1584 O OD1 . ASP   A 1 196 ? 153.950 155.224 126.176 1.00 59.76  ? 222 ASP   A OD1 1 
ATOM   1585 O OD2 . ASP   A 1 196 ? 154.691 155.131 128.239 1.00 63.08  ? 222 ASP   A OD2 1 
ATOM   1586 N N   . TRP   A 1 197 ? 150.922 151.088 126.382 1.00 50.35  ? 223 TRP   A N   1 
ATOM   1587 C CA  . TRP   A 1 197 ? 150.430 149.717 126.429 1.00 49.94  ? 223 TRP   A CA  1 
ATOM   1588 C C   . TRP   A 1 197 ? 150.001 149.204 125.065 1.00 50.41  ? 223 TRP   A C   1 
ATOM   1589 O O   . TRP   A 1 197 ? 150.250 148.041 124.740 1.00 51.65  ? 223 TRP   A O   1 
ATOM   1590 C CB  . TRP   A 1 197 ? 149.250 149.604 127.399 1.00 48.75  ? 223 TRP   A CB  1 
ATOM   1591 C CG  . TRP   A 1 197 ? 148.732 148.207 127.536 1.00 48.44  ? 223 TRP   A CG  1 
ATOM   1592 C CD1 . TRP   A 1 197 ? 147.704 147.642 126.843 1.00 50.40  ? 223 TRP   A CD1 1 
ATOM   1593 C CD2 . TRP   A 1 197 ? 149.219 147.196 128.421 1.00 46.05  ? 223 TRP   A CD2 1 
ATOM   1594 N NE1 . TRP   A 1 197 ? 147.524 146.343 127.239 1.00 49.76  ? 223 TRP   A NE1 1 
ATOM   1595 C CE2 . TRP   A 1 197 ? 148.443 146.045 128.209 1.00 46.54  ? 223 TRP   A CE2 1 
ATOM   1596 C CE3 . TRP   A 1 197 ? 150.239 147.152 129.371 1.00 48.14  ? 223 TRP   A CE3 1 
ATOM   1597 C CZ2 . TRP   A 1 197 ? 148.652 144.867 128.912 1.00 52.86  ? 223 TRP   A CZ2 1 
ATOM   1598 C CZ3 . TRP   A 1 197 ? 150.444 145.981 130.066 1.00 52.12  ? 223 TRP   A CZ3 1 
ATOM   1599 C CH2 . TRP   A 1 197 ? 149.657 144.856 129.834 1.00 56.62  ? 223 TRP   A CH2 1 
ATOM   1600 N N   . VAL   A 1 198 ? 149.360 150.045 124.253 1.00 49.06  ? 224 VAL   A N   1 
ATOM   1601 C CA  . VAL   A 1 198 ? 148.932 149.607 122.932 1.00 48.06  ? 224 VAL   A CA  1 
ATOM   1602 C C   . VAL   A 1 198 ? 150.100 149.503 121.961 1.00 51.07  ? 224 VAL   A C   1 
ATOM   1603 O O   . VAL   A 1 198 ? 149.971 148.844 120.924 1.00 55.61  ? 224 VAL   A O   1 
ATOM   1604 C CB  . VAL   A 1 198 ? 147.854 150.553 122.372 1.00 47.79  ? 224 VAL   A CB  1 
ATOM   1605 C CG1 . VAL   A 1 198 ? 146.712 150.695 123.355 1.00 47.32  ? 224 VAL   A CG1 1 
ATOM   1606 C CG2 . VAL   A 1 198 ? 148.445 151.915 122.029 1.00 49.03  ? 224 VAL   A CG2 1 
ATOM   1607 N N   . GLU   A 1 199 ? 151.238 150.128 122.267 1.00 46.76  ? 225 GLU   A N   1 
ATOM   1608 C CA  . GLU   A 1 199 ? 152.393 150.149 121.380 1.00 45.61  ? 225 GLU   A CA  1 
ATOM   1609 C C   . GLU   A 1 199 ? 153.493 149.182 121.798 1.00 46.74  ? 225 GLU   A C   1 
ATOM   1610 O O   . GLU   A 1 199 ? 154.521 149.112 121.119 1.00 49.52  ? 225 GLU   A O   1 
ATOM   1611 C CB  . GLU   A 1 199 ? 152.955 151.568 121.293 1.00 49.10  ? 225 GLU   A CB  1 
ATOM   1612 C CG  . GLU   A 1 199 ? 151.991 152.554 120.657 1.00 52.48  ? 225 GLU   A CG  1 
ATOM   1613 C CD  . GLU   A 1 199 ? 152.577 153.942 120.507 1.00 58.57  ? 225 GLU   A CD  1 
ATOM   1614 O OE1 . GLU   A 1 199 ? 153.799 154.099 120.703 1.00 58.74  ? 225 GLU   A OE1 1 
ATOM   1615 O OE2 . GLU   A 1 199 ? 151.813 154.878 120.195 1.00 55.92  ? 225 GLU   A OE2 1 
ATOM   1616 N N   . GLY   A 1 200 ? 153.312 148.443 122.889 1.00 49.79  ? 226 GLY   A N   1 
ATOM   1617 C CA  . GLY   A 1 200 ? 154.223 147.371 123.238 1.00 49.92  ? 226 GLY   A CA  1 
ATOM   1618 C C   . GLY   A 1 200 ? 155.377 147.739 124.141 1.00 50.05  ? 226 GLY   A C   1 
ATOM   1619 O O   . GLY   A 1 200 ? 156.337 146.966 124.225 1.00 55.56  ? 226 GLY   A O   1 
ATOM   1620 N N   . TYR   A 1 201 ? 155.321 148.883 124.826 1.00 44.07  ? 227 TYR   A N   1 
ATOM   1621 C CA  . TYR   A 1 201 ? 156.448 149.303 125.654 1.00 44.64  ? 227 TYR   A CA  1 
ATOM   1622 C C   . TYR   A 1 201 ? 156.386 148.688 127.047 1.00 51.50  ? 227 TYR   A C   1 
ATOM   1623 O O   . TYR   A 1 201 ? 157.390 148.172 127.548 1.00 58.17  ? 227 TYR   A O   1 
ATOM   1624 C CB  . TYR   A 1 201 ? 156.500 150.827 125.739 1.00 45.85  ? 227 TYR   A CB  1 
ATOM   1625 C CG  . TYR   A 1 201 ? 156.878 151.495 124.438 1.00 48.37  ? 227 TYR   A CG  1 
ATOM   1626 C CD1 . TYR   A 1 201 ? 158.128 151.301 123.873 1.00 43.75  ? 227 TYR   A CD1 1 
ATOM   1627 C CD2 . TYR   A 1 201 ? 155.989 152.327 123.779 1.00 53.65  ? 227 TYR   A CD2 1 
ATOM   1628 C CE1 . TYR   A 1 201 ? 158.476 151.903 122.687 1.00 43.50  ? 227 TYR   A CE1 1 
ATOM   1629 C CE2 . TYR   A 1 201 ? 156.331 152.937 122.593 1.00 51.18  ? 227 TYR   A CE2 1 
ATOM   1630 C CZ  . TYR   A 1 201 ? 157.575 152.723 122.052 1.00 47.55  ? 227 TYR   A CZ  1 
ATOM   1631 O OH  . TYR   A 1 201 ? 157.916 153.331 120.869 1.00 48.69  ? 227 TYR   A OH  1 
ATOM   1632 N N   . SER   A 1 202 ? 155.224 148.735 127.691 1.00 50.36  ? 228 SER   A N   1 
ATOM   1633 C CA  . SER   A 1 202 ? 155.081 148.130 129.008 1.00 47.48  ? 228 SER   A CA  1 
ATOM   1634 C C   . SER   A 1 202 ? 155.173 146.614 128.893 1.00 53.01  ? 228 SER   A C   1 
ATOM   1635 O O   . SER   A 1 202 ? 154.535 146.012 128.028 1.00 60.05  ? 228 SER   A O   1 
ATOM   1636 C CB  . SER   A 1 202 ? 153.748 148.533 129.626 1.00 49.35  ? 228 SER   A CB  1 
ATOM   1637 O OG  . SER   A 1 202 ? 153.479 149.903 129.396 1.00 55.16  ? 228 SER   A OG  1 
ATOM   1638 N N   . MET   A 1 203 ? 155.967 145.995 129.764 1.00 51.42  ? 229 MET   A N   1 
ATOM   1639 C CA  . MET   A 1 203 ? 156.177 144.544 129.740 1.00 54.51  ? 229 MET   A CA  1 
ATOM   1640 C C   . MET   A 1 203 ? 156.735 144.090 128.395 1.00 57.94  ? 229 MET   A C   1 
ATOM   1641 O O   . MET   A 1 203 ? 156.264 143.120 127.800 1.00 59.28  ? 229 MET   A O   1 
ATOM   1642 C CB  . MET   A 1 203 ? 154.885 143.790 130.064 1.00 59.35  ? 229 MET   A CB  1 
ATOM   1643 C CG  . MET   A 1 203 ? 154.361 144.010 131.467 1.00 63.48  ? 229 MET   A CG  1 
ATOM   1644 S SD  . MET   A 1 203 ? 152.578 143.767 131.595 1.00 83.19  ? 229 MET   A SD  1 
ATOM   1645 C CE  . MET   A 1 203 ? 152.312 142.357 130.525 1.00 70.93  ? 229 MET   A CE  1 
ATOM   1646 N N   . GLU   A 1 204 ? 157.756 144.795 127.910 1.00 58.30  ? 230 GLU   A N   1 
ATOM   1647 C CA  . GLU   A 1 204 ? 158.319 144.485 126.602 1.00 60.48  ? 230 GLU   A CA  1 
ATOM   1648 C C   . GLU   A 1 204 ? 159.133 143.199 126.602 1.00 64.29  ? 230 GLU   A C   1 
ATOM   1649 O O   . GLU   A 1 204 ? 159.348 142.625 125.530 1.00 69.70  ? 230 GLU   A O   1 
ATOM   1650 C CB  . GLU   A 1 204 ? 159.189 145.651 126.127 1.00 63.46  ? 230 GLU   A CB  1 
ATOM   1651 C CG  . GLU   A 1 204 ? 159.636 145.550 124.678 1.00 72.56  ? 230 GLU   A CG  1 
ATOM   1652 C CD  . GLU   A 1 204 ? 160.369 146.790 124.208 1.00 80.88  ? 230 GLU   A CD  1 
ATOM   1653 O OE1 . GLU   A 1 204 ? 160.575 147.708 125.029 1.00 76.75  ? 230 GLU   A OE1 1 
ATOM   1654 O OE2 . GLU   A 1 204 ? 160.740 146.847 123.016 1.00 84.36  ? 230 GLU   A OE2 1 
ATOM   1655 N N   . TYR   A 1 205 ? 159.579 142.731 127.768 1.00 63.12  ? 231 TYR   A N   1 
ATOM   1656 C CA  . TYR   A 1 205 ? 160.469 141.582 127.873 1.00 67.56  ? 231 TYR   A CA  1 
ATOM   1657 C C   . TYR   A 1 205 ? 159.796 140.362 128.489 1.00 63.07  ? 231 TYR   A C   1 
ATOM   1658 O O   . TYR   A 1 205 ? 160.493 139.421 128.881 1.00 67.80  ? 231 TYR   A O   1 
ATOM   1659 C CB  . TYR   A 1 205 ? 161.706 141.953 128.696 1.00 74.37  ? 231 TYR   A CB  1 
ATOM   1660 C CG  . TYR   A 1 205 ? 162.527 143.096 128.132 1.00 78.33  ? 231 TYR   A CG  1 
ATOM   1661 C CD1 . TYR   A 1 205 ? 162.926 143.107 126.802 1.00 76.69  ? 231 TYR   A CD1 1 
ATOM   1662 C CD2 . TYR   A 1 205 ? 162.903 144.163 128.935 1.00 80.85  ? 231 TYR   A CD2 1 
ATOM   1663 C CE1 . TYR   A 1 205 ? 163.675 144.146 126.291 1.00 80.08  ? 231 TYR   A CE1 1 
ATOM   1664 C CE2 . TYR   A 1 205 ? 163.652 145.206 128.432 1.00 87.56  ? 231 TYR   A CE2 1 
ATOM   1665 C CZ  . TYR   A 1 205 ? 164.035 145.193 127.109 1.00 88.56  ? 231 TYR   A CZ  1 
ATOM   1666 O OH  . TYR   A 1 205 ? 164.782 146.232 126.603 1.00 89.95  ? 231 TYR   A OH  1 
ATOM   1667 N N   . LEU   A 1 206 ? 158.467 140.345 128.579 1.00 55.93  ? 232 LEU   A N   1 
ATOM   1668 C CA  . LEU   A 1 206 ? 157.763 139.236 129.208 1.00 56.15  ? 232 LEU   A CA  1 
ATOM   1669 C C   . LEU   A 1 206 ? 157.425 138.112 128.237 1.00 61.30  ? 232 LEU   A C   1 
ATOM   1670 O O   . LEU   A 1 206 ? 156.986 137.046 128.679 1.00 65.03  ? 232 LEU   A O   1 
ATOM   1671 C CB  . LEU   A 1 206 ? 156.478 139.744 129.872 1.00 55.40  ? 232 LEU   A CB  1 
ATOM   1672 C CG  . LEU   A 1 206 ? 155.771 138.820 130.866 1.00 58.83  ? 232 LEU   A CG  1 
ATOM   1673 C CD1 . LEU   A 1 206 ? 156.648 138.517 132.074 1.00 57.44  ? 232 LEU   A CD1 1 
ATOM   1674 C CD2 . LEU   A 1 206 ? 154.464 139.432 131.302 1.00 62.19  ? 232 LEU   A CD2 1 
ATOM   1675 N N   . SER   A 1 207 ? 157.642 138.302 126.938 1.00 60.85  ? 233 SER   A N   1 
ATOM   1676 C CA  . SER   A 1 207 ? 157.345 137.263 125.963 1.00 59.60  ? 233 SER   A CA  1 
ATOM   1677 C C   . SER   A 1 207 ? 158.408 136.175 125.916 1.00 61.90  ? 233 SER   A C   1 
ATOM   1678 O O   . SER   A 1 207 ? 158.220 135.184 125.203 1.00 67.35  ? 233 SER   A O   1 
ATOM   1679 C CB  . SER   A 1 207 ? 157.184 137.885 124.576 1.00 60.61  ? 233 SER   A CB  1 
ATOM   1680 O OG  . SER   A 1 207 ? 156.785 136.915 123.624 1.00 65.90  ? 233 SER   A OG  1 
ATOM   1681 N N   . ARG   A 1 208 ? 159.510 136.326 126.649 1.00 59.93  ? 234 ARG   A N   1 
ATOM   1682 C CA  . ARG   A 1 208 ? 160.558 135.318 126.668 1.00 60.14  ? 234 ARG   A CA  1 
ATOM   1683 C C   . ARG   A 1 208 ? 160.247 134.149 127.591 1.00 58.60  ? 234 ARG   A C   1 
ATOM   1684 O O   . ARG   A 1 208 ? 160.928 133.123 127.504 1.00 64.19  ? 234 ARG   A O   1 
ATOM   1685 C CB  . ARG   A 1 208 ? 161.883 135.952 127.093 1.00 63.82  ? 234 ARG   A CB  1 
ATOM   1686 C CG  . ARG   A 1 208 ? 162.436 136.954 126.100 1.00 69.73  ? 234 ARG   A CG  1 
ATOM   1687 C CD  . ARG   A 1 208 ? 163.717 137.586 126.607 1.00 74.17  ? 234 ARG   A CD  1 
ATOM   1688 N NE  . ARG   A 1 208 ? 164.259 138.557 125.664 1.00 82.52  ? 234 ARG   A NE  1 
ATOM   1689 C CZ  . ARG   A 1 208 ? 165.375 139.253 125.847 1.00 88.36  ? 234 ARG   A CZ  1 
ATOM   1690 N NH1 . ARG   A 1 208 ? 166.112 139.115 126.940 1.00 88.90  ? 234 ARG   A NH1 1 
ATOM   1691 N NH2 . ARG   A 1 208 ? 165.764 140.112 124.909 1.00 87.71  ? 234 ARG   A NH2 1 
ATOM   1692 N N   . HIS   A 1 209 ? 159.249 134.270 128.460 1.00 57.38  ? 235 HIS   A N   1 
ATOM   1693 C CA  . HIS   A 1 209 ? 158.972 133.216 129.423 1.00 60.09  ? 235 HIS   A CA  1 
ATOM   1694 C C   . HIS   A 1 209 ? 158.481 131.958 128.716 1.00 63.28  ? 235 HIS   A C   1 
ATOM   1695 O O   . HIS   A 1 209 ? 157.795 132.017 127.693 1.00 64.70  ? 235 HIS   A O   1 
ATOM   1696 C CB  . HIS   A 1 209 ? 157.936 133.682 130.441 1.00 58.08  ? 235 HIS   A CB  1 
ATOM   1697 C CG  . HIS   A 1 209 ? 157.955 132.900 131.715 1.00 59.08  ? 235 HIS   A CG  1 
ATOM   1698 N ND1 . HIS   A 1 209 ? 157.173 131.784 131.916 1.00 62.85  ? 235 HIS   A ND1 1 
ATOM   1699 C CD2 . HIS   A 1 209 ? 158.664 133.072 132.855 1.00 58.58  ? 235 HIS   A CD2 1 
ATOM   1700 C CE1 . HIS   A 1 209 ? 157.397 131.304 133.126 1.00 63.03  ? 235 HIS   A CE1 1 
ATOM   1701 N NE2 . HIS   A 1 209 ? 158.299 132.066 133.716 1.00 60.32  ? 235 HIS   A NE2 1 
ATOM   1702 N N   . TRP   A 1 210 ? 158.839 130.805 129.284 1.00 61.32  ? 236 TRP   A N   1 
ATOM   1703 C CA  . TRP   A 1 210 ? 158.586 129.531 128.620 1.00 61.30  ? 236 TRP   A CA  1 
ATOM   1704 C C   . TRP   A 1 210 ? 157.101 129.208 128.507 1.00 64.17  ? 236 TRP   A C   1 
ATOM   1705 O O   . TRP   A 1 210 ? 156.734 128.334 127.715 1.00 70.06  ? 236 TRP   A O   1 
ATOM   1706 C CB  . TRP   A 1 210 ? 159.311 128.403 129.358 1.00 56.92  ? 236 TRP   A CB  1 
ATOM   1707 C CG  . TRP   A 1 210 ? 158.838 128.183 130.758 1.00 57.00  ? 236 TRP   A CG  1 
ATOM   1708 C CD1 . TRP   A 1 210 ? 159.313 128.781 131.884 1.00 59.62  ? 236 TRP   A CD1 1 
ATOM   1709 C CD2 . TRP   A 1 210 ? 157.799 127.296 131.182 1.00 60.32  ? 236 TRP   A CD2 1 
ATOM   1710 N NE1 . TRP   A 1 210 ? 158.631 128.327 132.985 1.00 59.81  ? 236 TRP   A NE1 1 
ATOM   1711 C CE2 . TRP   A 1 210 ? 157.695 127.414 132.580 1.00 59.58  ? 236 TRP   A CE2 1 
ATOM   1712 C CE3 . TRP   A 1 210 ? 156.943 126.416 130.515 1.00 65.21  ? 236 TRP   A CE3 1 
ATOM   1713 C CZ2 . TRP   A 1 210 ? 156.773 126.684 133.324 1.00 61.10  ? 236 TRP   A CZ2 1 
ATOM   1714 C CZ3 . TRP   A 1 210 ? 156.028 125.692 131.255 1.00 67.68  ? 236 TRP   A CZ3 1 
ATOM   1715 C CH2 . TRP   A 1 210 ? 155.949 125.831 132.645 1.00 64.02  ? 236 TRP   A CH2 1 
ATOM   1716 N N   . LEU   A 1 211 ? 156.240 129.877 129.278 1.00 63.30  ? 237 LEU   A N   1 
ATOM   1717 C CA  . LEU   A 1 211 ? 154.803 129.672 129.121 1.00 65.29  ? 237 LEU   A CA  1 
ATOM   1718 C C   . LEU   A 1 211 ? 154.320 130.115 127.746 1.00 67.19  ? 237 LEU   A C   1 
ATOM   1719 O O   . LEU   A 1 211 ? 153.322 129.588 127.242 1.00 68.50  ? 237 LEU   A O   1 
ATOM   1720 C CB  . LEU   A 1 211 ? 154.040 130.425 130.211 1.00 66.07  ? 237 LEU   A CB  1 
ATOM   1721 C CG  . LEU   A 1 211 ? 154.222 129.960 131.659 1.00 65.76  ? 237 LEU   A CG  1 
ATOM   1722 C CD1 . LEU   A 1 211 ? 153.538 130.914 132.630 1.00 65.25  ? 237 LEU   A CD1 1 
ATOM   1723 C CD2 . LEU   A 1 211 ? 153.687 128.552 131.853 1.00 64.69  ? 237 LEU   A CD2 1 
ATOM   1724 N N   . PHE   A 1 212 ? 155.006 131.074 127.127 1.00 62.82  ? 238 PHE   A N   1 
ATOM   1725 C CA  . PHE   A 1 212 ? 154.678 131.542 125.788 1.00 63.06  ? 238 PHE   A CA  1 
ATOM   1726 C C   . PHE   A 1 212 ? 155.383 130.749 124.693 1.00 67.81  ? 238 PHE   A C   1 
ATOM   1727 O O   . PHE   A 1 212 ? 155.367 131.173 123.533 1.00 71.35  ? 238 PHE   A O   1 
ATOM   1728 C CB  . PHE   A 1 212 ? 155.021 133.026 125.655 1.00 64.01  ? 238 PHE   A CB  1 
ATOM   1729 C CG  . PHE   A 1 212 ? 154.124 133.929 126.446 1.00 63.71  ? 238 PHE   A CG  1 
ATOM   1730 C CD1 . PHE   A 1 212 ? 152.871 134.258 125.979 1.00 64.88  ? 238 PHE   A CD1 1 
ATOM   1731 C CD2 . PHE   A 1 212 ? 154.542 134.461 127.650 1.00 62.26  ? 238 PHE   A CD2 1 
ATOM   1732 C CE1 . PHE   A 1 212 ? 152.048 135.092 126.699 1.00 65.63  ? 238 PHE   A CE1 1 
ATOM   1733 C CE2 . PHE   A 1 212 ? 153.723 135.295 128.372 1.00 62.83  ? 238 PHE   A CE2 1 
ATOM   1734 C CZ  . PHE   A 1 212 ? 152.475 135.609 127.895 1.00 64.84  ? 238 PHE   A CZ  1 
ATOM   1735 N N   . SER   A 1 213 ? 155.997 129.615 125.030 1.00 68.55  ? 239 SER   A N   1 
ATOM   1736 C CA  . SER   A 1 213 ? 156.693 128.815 124.024 1.00 66.24  ? 239 SER   A CA  1 
ATOM   1737 C C   . SER   A 1 213 ? 155.801 128.347 122.876 1.00 66.13  ? 239 SER   A C   1 
ATOM   1738 O O   . SER   A 1 213 ? 156.244 128.443 121.719 1.00 70.11  ? 239 SER   A O   1 
ATOM   1739 C CB  . SER   A 1 213 ? 157.381 127.627 124.705 1.00 67.33  ? 239 SER   A CB  1 
ATOM   1740 O OG  . SER   A 1 213 ? 156.502 126.926 125.565 1.00 72.86  ? 239 SER   A OG  1 
ATOM   1741 N N   . PRO   A 1 214 ? 154.582 127.819 123.092 1.00 62.43  ? 240 PRO   A N   1 
ATOM   1742 C CA  . PRO   A 1 214 ? 153.802 127.363 121.924 1.00 64.63  ? 240 PRO   A CA  1 
ATOM   1743 C C   . PRO   A 1 214 ? 153.473 128.462 120.929 1.00 69.19  ? 240 PRO   A C   1 
ATOM   1744 O O   . PRO   A 1 214 ? 153.504 128.214 119.715 1.00 76.01  ? 240 PRO   A O   1 
ATOM   1745 C CB  . PRO   A 1 214 ? 152.534 126.770 122.553 1.00 67.02  ? 240 PRO   A CB  1 
ATOM   1746 C CG  . PRO   A 1 214 ? 152.461 127.342 123.893 1.00 67.50  ? 240 PRO   A CG  1 
ATOM   1747 C CD  . PRO   A 1 214 ? 153.865 127.507 124.343 1.00 66.96  ? 240 PRO   A CD  1 
ATOM   1748 N N   . PHE   A 1 215 ? 153.187 129.678 121.405 1.00 66.07  ? 241 PHE   A N   1 
ATOM   1749 C CA  . PHE   A 1 215 ? 152.909 130.783 120.492 1.00 66.16  ? 241 PHE   A CA  1 
ATOM   1750 C C   . PHE   A 1 215 ? 154.080 131.033 119.554 1.00 68.29  ? 241 PHE   A C   1 
ATOM   1751 O O   . PHE   A 1 215 ? 153.879 131.419 118.398 1.00 70.15  ? 241 PHE   A O   1 
ATOM   1752 C CB  . PHE   A 1 215 ? 152.602 132.061 121.274 1.00 68.27  ? 241 PHE   A CB  1 
ATOM   1753 C CG  . PHE   A 1 215 ? 151.396 131.966 122.162 1.00 67.16  ? 241 PHE   A CG  1 
ATOM   1754 C CD1 . PHE   A 1 215 ? 150.138 132.244 121.673 1.00 67.63  ? 241 PHE   A CD1 1 
ATOM   1755 C CD2 . PHE   A 1 215 ? 151.528 131.621 123.495 1.00 68.80  ? 241 PHE   A CD2 1 
ATOM   1756 C CE1 . PHE   A 1 215 ? 149.032 132.166 122.486 1.00 72.88  ? 241 PHE   A CE1 1 
ATOM   1757 C CE2 . PHE   A 1 215 ? 150.424 131.541 124.314 1.00 71.26  ? 241 PHE   A CE2 1 
ATOM   1758 C CZ  . PHE   A 1 215 ? 149.175 131.815 123.809 1.00 73.34  ? 241 PHE   A CZ  1 
ATOM   1759 N N   . LYS   A 1 216 ? 155.306 130.806 120.027 1.00 69.59  ? 242 LYS   A N   1 
ATOM   1760 C CA  . LYS   A 1 216 ? 156.487 131.028 119.208 1.00 70.11  ? 242 LYS   A CA  1 
ATOM   1761 C C   . LYS   A 1 216 ? 156.607 130.038 118.057 1.00 73.35  ? 242 LYS   A C   1 
ATOM   1762 O O   . LYS   A 1 216 ? 157.425 130.264 117.160 1.00 72.91  ? 242 LYS   A O   1 
ATOM   1763 C CB  . LYS   A 1 216 ? 157.741 130.961 120.077 1.00 72.35  ? 242 LYS   A CB  1 
ATOM   1764 C CG  . LYS   A 1 216 ? 157.780 132.024 121.157 1.00 75.34  ? 242 LYS   A CG  1 
ATOM   1765 C CD  . LYS   A 1 216 ? 159.102 132.020 121.902 1.00 77.00  ? 242 LYS   A CD  1 
ATOM   1766 C CE  . LYS   A 1 216 ? 159.082 132.995 123.065 1.00 72.87  ? 242 LYS   A CE  1 
ATOM   1767 N NZ  . LYS   A 1 216 ? 158.772 134.382 122.628 1.00 73.73  ? 242 LYS   A NZ  1 
ATOM   1768 N N   . LEU   A 1 217 ? 155.827 128.953 118.056 1.00 74.59  ? 243 LEU   A N   1 
ATOM   1769 C CA  . LEU   A 1 217 ? 155.830 128.057 116.907 1.00 71.27  ? 243 LEU   A CA  1 
ATOM   1770 C C   . LEU   A 1 217 ? 155.143 128.671 115.693 1.00 71.47  ? 243 LEU   A C   1 
ATOM   1771 O O   . LEU   A 1 217 ? 155.418 128.243 114.567 1.00 74.34  ? 243 LEU   A O   1 
ATOM   1772 C CB  . LEU   A 1 217 ? 155.160 126.731 117.269 1.00 69.81  ? 243 LEU   A CB  1 
ATOM   1773 C CG  . LEU   A 1 217 ? 155.831 125.904 118.367 1.00 72.57  ? 243 LEU   A CG  1 
ATOM   1774 C CD1 . LEU   A 1 217 ? 154.973 124.698 118.712 1.00 73.75  ? 243 LEU   A CD1 1 
ATOM   1775 C CD2 . LEU   A 1 217 ? 157.227 125.463 117.956 1.00 71.64  ? 243 LEU   A CD2 1 
ATOM   1776 N N   . LEU   A 1 218 ? 154.262 129.659 115.894 1.00 68.06  ? 244 LEU   A N   1 
ATOM   1777 C CA  . LEU   A 1 218 ? 153.540 130.311 114.809 1.00 65.68  ? 244 LEU   A CA  1 
ATOM   1778 C C   . LEU   A 1 218 ? 153.840 131.796 114.652 1.00 68.39  ? 244 LEU   A C   1 
ATOM   1779 O O   . LEU   A 1 218 ? 153.577 132.339 113.574 1.00 73.65  ? 244 LEU   A O   1 
ATOM   1780 C CB  . LEU   A 1 218 ? 152.022 130.156 114.999 1.00 70.64  ? 244 LEU   A CB  1 
ATOM   1781 C CG  . LEU   A 1 218 ? 151.373 128.764 114.940 1.00 77.96  ? 244 LEU   A CG  1 
ATOM   1782 C CD1 . LEU   A 1 218 ? 151.767 128.016 113.670 1.00 78.25  ? 244 LEU   A CD1 1 
ATOM   1783 C CD2 . LEU   A 1 218 ? 151.686 127.927 116.176 1.00 75.09  ? 244 LEU   A CD2 1 
ATOM   1784 N N   . LEU   A 1 219 ? 154.376 132.465 115.675 1.00 70.34  ? 245 LEU   A N   1 
ATOM   1785 C CA  . LEU   A 1 219 ? 154.611 133.904 115.648 1.00 70.01  ? 245 LEU   A CA  1 
ATOM   1786 C C   . LEU   A 1 219 ? 156.010 134.225 116.155 1.00 72.66  ? 245 LEU   A C   1 
ATOM   1787 O O   . LEU   A 1 219 ? 156.566 133.511 116.991 1.00 71.49  ? 245 LEU   A O   1 
ATOM   1788 C CB  . LEU   A 1 219 ? 153.582 134.656 116.501 1.00 68.65  ? 245 LEU   A CB  1 
ATOM   1789 C CG  . LEU   A 1 219 ? 152.138 134.681 116.000 1.00 71.64  ? 245 LEU   A CG  1 
ATOM   1790 C CD1 . LEU   A 1 219 ? 151.232 135.284 117.057 1.00 71.44  ? 245 LEU   A CD1 1 
ATOM   1791 C CD2 . LEU   A 1 219 ? 152.023 135.455 114.696 1.00 73.37  ? 245 LEU   A CD2 1 
ATOM   1792 N N   . SER   A 1 220 ? 156.575 135.313 115.639 1.00 75.40  ? 246 SER   A N   1 
ATOM   1793 C CA  . SER   A 1 220 ? 157.877 135.769 116.097 1.00 76.19  ? 246 SER   A CA  1 
ATOM   1794 C C   . SER   A 1 220 ? 157.771 136.342 117.509 1.00 73.57  ? 246 SER   A C   1 
ATOM   1795 O O   . SER   A 1 220 ? 156.681 136.537 118.054 1.00 75.73  ? 246 SER   A O   1 
ATOM   1796 C CB  . SER   A 1 220 ? 158.442 136.822 115.145 1.00 77.66  ? 246 SER   A CB  1 
ATOM   1797 O OG  . SER   A 1 220 ? 157.605 137.965 115.093 1.00 75.13  ? 246 SER   A OG  1 
ATOM   1798 N N   . GLU   A 1 221 ? 158.934 136.609 118.108 1.00 71.13  ? 247 GLU   A N   1 
ATOM   1799 C CA  . GLU   A 1 221 ? 158.957 137.147 119.464 1.00 70.97  ? 247 GLU   A CA  1 
ATOM   1800 C C   . GLU   A 1 221 ? 158.348 138.542 119.517 1.00 70.73  ? 247 GLU   A C   1 
ATOM   1801 O O   . GLU   A 1 221 ? 157.576 138.853 120.431 1.00 71.52  ? 247 GLU   A O   1 
ATOM   1802 C CB  . GLU   A 1 221 ? 160.389 137.169 119.992 1.00 69.41  ? 247 GLU   A CB  1 
ATOM   1803 C CG  . GLU   A 1 221 ? 160.498 137.435 121.482 1.00 71.46  ? 247 GLU   A CG  1 
ATOM   1804 C CD  . GLU   A 1 221 ? 161.934 137.450 121.966 1.00 78.32  ? 247 GLU   A CD  1 
ATOM   1805 O OE1 . GLU   A 1 221 ? 162.834 137.096 121.175 1.00 78.36  ? 247 GLU   A OE1 1 
ATOM   1806 O OE2 . GLU   A 1 221 ? 162.165 137.820 123.136 1.00 79.48  ? 247 GLU   A OE2 1 
ATOM   1807 N N   . GLU   A 1 222 ? 158.683 139.396 118.549 1.00 68.10  ? 248 GLU   A N   1 
ATOM   1808 C CA  . GLU   A 1 222 ? 158.158 140.758 118.554 1.00 71.22  ? 248 GLU   A CA  1 
ATOM   1809 C C   . GLU   A 1 222 ? 156.647 140.772 118.357 1.00 69.27  ? 248 GLU   A C   1 
ATOM   1810 O O   . GLU   A 1 222 ? 155.939 141.552 119.004 1.00 68.38  ? 248 GLU   A O   1 
ATOM   1811 C CB  . GLU   A 1 222 ? 158.860 141.597 117.482 1.00 78.56  ? 248 GLU   A CB  1 
ATOM   1812 C CG  . GLU   A 1 222 ? 158.702 141.097 116.051 1.00 83.10  ? 248 GLU   A CG  1 
ATOM   1813 C CD  . GLU   A 1 222 ? 159.531 141.894 115.062 1.00 86.75  ? 248 GLU   A CD  1 
ATOM   1814 O OE1 . GLU   A 1 222 ? 160.202 142.857 115.488 1.00 87.69  ? 248 GLU   A OE1 1 
ATOM   1815 O OE2 . GLU   A 1 222 ? 159.512 141.556 113.860 1.00 86.04  ? 248 GLU   A OE2 1 
ATOM   1816 N N   . LEU   A 1 223 ? 156.132 139.922 117.466 1.00 68.98  ? 249 LEU   A N   1 
ATOM   1817 C CA  . LEU   A 1 223 ? 154.686 139.851 117.275 1.00 66.51  ? 249 LEU   A CA  1 
ATOM   1818 C C   . LEU   A 1 223 ? 153.999 139.219 118.479 1.00 63.79  ? 249 LEU   A C   1 
ATOM   1819 O O   . LEU   A 1 223 ? 152.894 139.628 118.857 1.00 67.73  ? 249 LEU   A O   1 
ATOM   1820 C CB  . LEU   A 1 223 ? 154.353 139.062 116.008 1.00 72.56  ? 249 LEU   A CB  1 
ATOM   1821 C CG  . LEU   A 1 223 ? 154.173 139.868 114.721 1.00 77.90  ? 249 LEU   A CG  1 
ATOM   1822 C CD1 . LEU   A 1 223 ? 155.448 140.603 114.349 1.00 76.21  ? 249 LEU   A CD1 1 
ATOM   1823 C CD2 . LEU   A 1 223 ? 153.725 138.958 113.587 1.00 74.90  ? 249 LEU   A CD2 1 
ATOM   1824 N N   . THR   A 1 224 ? 154.627 138.210 119.083 1.00 58.94  ? 250 THR   A N   1 
ATOM   1825 C CA  . THR   A 1 224 ? 154.048 137.594 120.269 1.00 55.55  ? 250 THR   A CA  1 
ATOM   1826 C C   . THR   A 1 224 ? 154.003 138.570 121.431 1.00 58.72  ? 250 THR   A C   1 
ATOM   1827 O O   . THR   A 1 224 ? 153.101 138.492 122.273 1.00 63.54  ? 250 THR   A O   1 
ATOM   1828 C CB  . THR   A 1 224 ? 154.841 136.351 120.663 1.00 60.68  ? 250 THR   A CB  1 
ATOM   1829 O OG1 . THR   A 1 224 ? 154.849 135.419 119.575 1.00 67.57  ? 250 THR   A OG1 1 
ATOM   1830 C CG2 . THR   A 1 224 ? 154.224 135.693 121.882 1.00 63.22  ? 250 THR   A CG2 1 
ATOM   1831 N N   . SER   A 1 225 ? 154.960 139.493 121.498 1.00 59.19  ? 251 SER   A N   1 
ATOM   1832 C CA  . SER   A 1 225 ? 154.998 140.468 122.578 1.00 57.62  ? 251 SER   A CA  1 
ATOM   1833 C C   . SER   A 1 225 ? 153.953 141.562 122.440 1.00 54.06  ? 251 SER   A C   1 
ATOM   1834 O O   . SER   A 1 225 ? 153.778 142.334 123.386 1.00 59.99  ? 251 SER   A O   1 
ATOM   1835 C CB  . SER   A 1 225 ? 156.379 141.116 122.656 1.00 61.71  ? 251 SER   A CB  1 
ATOM   1836 O OG  . SER   A 1 225 ? 156.343 142.276 123.468 1.00 59.52  ? 251 SER   A OG  1 
ATOM   1837 N N   . LEU   A 1 226 ? 153.266 141.653 121.302 1.00 50.18  ? 252 LEU   A N   1 
ATOM   1838 C CA  . LEU   A 1 226 ? 152.278 142.697 121.060 1.00 49.25  ? 252 LEU   A CA  1 
ATOM   1839 C C   . LEU   A 1 226 ? 150.875 142.141 120.903 1.00 51.51  ? 252 LEU   A C   1 
ATOM   1840 O O   . LEU   A 1 226 ? 149.950 142.607 121.579 1.00 56.49  ? 252 LEU   A O   1 
ATOM   1841 C CB  . LEU   A 1 226 ? 152.670 143.497 119.809 1.00 50.33  ? 252 LEU   A CB  1 
ATOM   1842 C CG  . LEU   A 1 226 ? 151.939 144.815 119.554 1.00 48.13  ? 252 LEU   A CG  1 
ATOM   1843 C CD1 . LEU   A 1 226 ? 152.277 145.847 120.612 1.00 49.92  ? 252 LEU   A CD1 1 
ATOM   1844 C CD2 . LEU   A 1 226 ? 152.278 145.339 118.177 1.00 48.28  ? 252 LEU   A CD2 1 
ATOM   1845 N N   . LEU   A 1 227 ? 150.685 141.154 120.028 1.00 53.87  ? 253 LEU   A N   1 
ATOM   1846 C CA  . LEU   A 1 227 ? 149.340 140.650 119.782 1.00 53.24  ? 253 LEU   A CA  1 
ATOM   1847 C C   . LEU   A 1 227 ? 148.800 139.892 120.986 1.00 56.54  ? 253 LEU   A C   1 
ATOM   1848 O O   . LEU   A 1 227 ? 147.615 140.010 121.319 1.00 59.79  ? 253 LEU   A O   1 
ATOM   1849 C CB  . LEU   A 1 227 ? 149.335 139.753 118.546 1.00 54.10  ? 253 LEU   A CB  1 
ATOM   1850 C CG  . LEU   A 1 227 ? 149.786 140.390 117.233 1.00 57.76  ? 253 LEU   A CG  1 
ATOM   1851 C CD1 . LEU   A 1 227 ? 149.852 139.341 116.138 1.00 62.93  ? 253 LEU   A CD1 1 
ATOM   1852 C CD2 . LEU   A 1 227 ? 148.859 141.523 116.829 1.00 57.09  ? 253 LEU   A CD2 1 
ATOM   1853 N N   . VAL   A 1 228 ? 149.649 139.113 121.651 1.00 56.15  ? 254 VAL   A N   1 
ATOM   1854 C CA  . VAL   A 1 228 ? 149.215 138.239 122.734 1.00 58.65  ? 254 VAL   A CA  1 
ATOM   1855 C C   . VAL   A 1 228 ? 149.264 138.989 124.058 1.00 59.82  ? 254 VAL   A C   1 
ATOM   1856 O O   . VAL   A 1 228 ? 148.266 139.056 124.782 1.00 64.71  ? 254 VAL   A O   1 
ATOM   1857 C CB  . VAL   A 1 228 ? 150.078 136.965 122.793 1.00 61.98  ? 254 VAL   A CB  1 
ATOM   1858 C CG1 . VAL   A 1 228 ? 149.710 136.123 124.004 1.00 66.42  ? 254 VAL   A CG1 1 
ATOM   1859 C CG2 . VAL   A 1 228 ? 149.921 136.157 121.514 1.00 63.22  ? 254 VAL   A CG2 1 
ATOM   1860 N N   . VAL   A 1 229 ? 150.427 139.552 124.386 1.00 51.84  ? 255 VAL   A N   1 
ATOM   1861 C CA  . VAL   A 1 229 ? 150.643 140.073 125.731 1.00 50.62  ? 255 VAL   A CA  1 
ATOM   1862 C C   . VAL   A 1 229 ? 149.824 141.338 125.966 1.00 52.93  ? 255 VAL   A C   1 
ATOM   1863 O O   . VAL   A 1 229 ? 149.158 141.474 126.998 1.00 59.92  ? 255 VAL   A O   1 
ATOM   1864 C CB  . VAL   A 1 229 ? 152.142 140.315 125.975 1.00 54.48  ? 255 VAL   A CB  1 
ATOM   1865 C CG1 . VAL   A 1 229 ? 152.366 140.891 127.364 1.00 59.41  ? 255 VAL   A CG1 1 
ATOM   1866 C CG2 . VAL   A 1 229 ? 152.926 139.019 125.792 1.00 59.63  ? 255 VAL   A CG2 1 
ATOM   1867 N N   . HIS   A 1 230 ? 149.851 142.280 125.023 1.00 49.64  ? 256 HIS   A N   1 
ATOM   1868 C CA  . HIS   A 1 230 ? 149.258 143.595 125.261 1.00 51.08  ? 256 HIS   A CA  1 
ATOM   1869 C C   . HIS   A 1 230 ? 147.810 143.679 124.783 1.00 51.04  ? 256 HIS   A C   1 
ATOM   1870 O O   . HIS   A 1 230 ? 146.892 143.906 125.582 1.00 54.06  ? 256 HIS   A O   1 
ATOM   1871 C CB  . HIS   A 1 230 ? 150.098 144.671 124.570 1.00 49.95  ? 256 HIS   A CB  1 
ATOM   1872 C CG  . HIS   A 1 230 ? 151.469 144.824 125.143 1.00 47.12  ? 256 HIS   A CG  1 
ATOM   1873 N ND1 . HIS   A 1 230 ? 152.412 143.823 125.093 1.00 50.80  ? 256 HIS   A ND1 1 
ATOM   1874 C CD2 . HIS   A 1 230 ? 152.053 145.860 125.785 1.00 46.93  ? 256 HIS   A CD2 1 
ATOM   1875 C CE1 . HIS   A 1 230 ? 153.520 144.237 125.679 1.00 51.64  ? 256 HIS   A CE1 1 
ATOM   1876 N NE2 . HIS   A 1 230 ? 153.329 145.471 126.103 1.00 48.68  ? 256 HIS   A NE2 1 
ATOM   1877 N N   . TRP   A 1 231 ? 147.593 143.480 123.483 1.00 47.86  ? 257 TRP   A N   1 
ATOM   1878 C CA  . TRP   A 1 231 ? 146.241 143.555 122.948 1.00 47.42  ? 257 TRP   A CA  1 
ATOM   1879 C C   . TRP   A 1 231 ? 145.386 142.427 123.500 1.00 50.22  ? 257 TRP   A C   1 
ATOM   1880 O O   . TRP   A 1 231 ? 144.199 142.622 123.795 1.00 53.81  ? 257 TRP   A O   1 
ATOM   1881 C CB  . TRP   A 1 231 ? 146.271 143.496 121.423 1.00 48.62  ? 257 TRP   A CB  1 
ATOM   1882 C CG  . TRP   A 1 231 ? 146.959 144.649 120.753 1.00 49.10  ? 257 TRP   A CG  1 
ATOM   1883 C CD1 . TRP   A 1 231 ? 147.508 145.745 121.346 1.00 46.34  ? 257 TRP   A CD1 1 
ATOM   1884 C CD2 . TRP   A 1 231 ? 147.163 144.812 119.347 1.00 51.38  ? 257 TRP   A CD2 1 
ATOM   1885 N NE1 . TRP   A 1 231 ? 148.043 146.576 120.399 1.00 46.47  ? 257 TRP   A NE1 1 
ATOM   1886 C CE2 . TRP   A 1 231 ? 147.844 146.026 119.162 1.00 49.67  ? 257 TRP   A CE2 1 
ATOM   1887 C CE3 . TRP   A 1 231 ? 146.836 144.044 118.226 1.00 50.63  ? 257 TRP   A CE3 1 
ATOM   1888 C CZ2 . TRP   A 1 231 ? 148.204 146.492 117.904 1.00 52.60  ? 257 TRP   A CZ2 1 
ATOM   1889 C CZ3 . TRP   A 1 231 ? 147.194 144.508 116.979 1.00 50.98  ? 257 TRP   A CZ3 1 
ATOM   1890 C CH2 . TRP   A 1 231 ? 147.872 145.719 116.827 1.00 53.00  ? 257 TRP   A CH2 1 
ATOM   1891 N N   . GLY   A 1 232 ? 145.979 141.244 123.655 1.00 48.72  ? 258 GLY   A N   1 
ATOM   1892 C CA  . GLY   A 1 232 ? 145.258 140.146 124.267 1.00 50.19  ? 258 GLY   A CA  1 
ATOM   1893 C C   . GLY   A 1 232 ? 144.836 140.459 125.686 1.00 50.98  ? 258 GLY   A C   1 
ATOM   1894 O O   . GLY   A 1 232 ? 143.703 140.184 126.075 1.00 55.17  ? 258 GLY   A O   1 
ATOM   1895 N N   . GLY   A 1 233 ? 145.730 141.063 126.469 1.00 49.49  ? 259 GLY   A N   1 
ATOM   1896 C CA  . GLY   A 1 233 ? 145.376 141.431 127.831 1.00 51.19  ? 259 GLY   A CA  1 
ATOM   1897 C C   . GLY   A 1 233 ? 144.262 142.458 127.895 1.00 49.81  ? 259 GLY   A C   1 
ATOM   1898 O O   . GLY   A 1 233 ? 143.331 142.328 128.694 1.00 53.92  ? 259 GLY   A O   1 
ATOM   1899 N N   . LEU   A 1 234 ? 144.340 143.493 127.056 1.00 47.77  ? 260 LEU   A N   1 
ATOM   1900 C CA  . LEU   A 1 234 ? 143.305 144.525 127.053 1.00 48.39  ? 260 LEU   A CA  1 
ATOM   1901 C C   . LEU   A 1 234 ? 141.947 143.948 126.657 1.00 50.27  ? 260 LEU   A C   1 
ATOM   1902 O O   . LEU   A 1 234 ? 140.926 144.176 127.336 1.00 53.88  ? 260 LEU   A O   1 
ATOM   1903 C CB  . LEU   A 1 234 ? 143.722 145.645 126.099 1.00 45.24  ? 260 LEU   A CB  1 
ATOM   1904 C CG  . LEU   A 1 234 ? 142.693 146.692 125.682 1.00 47.59  ? 260 LEU   A CG  1 
ATOM   1905 C CD1 . LEU   A 1 234 ? 142.056 147.326 126.897 1.00 51.19  ? 260 LEU   A CD1 1 
ATOM   1906 C CD2 . LEU   A 1 234 ? 143.357 147.744 124.816 1.00 45.67  ? 260 LEU   A CD2 1 
ATOM   1907 N N   . LEU   A 1 235 ? 141.918 143.196 125.553 1.00 48.20  ? 261 LEU   A N   1 
ATOM   1908 C CA  . LEU   A 1 235 ? 140.669 142.598 125.106 1.00 46.20  ? 261 LEU   A CA  1 
ATOM   1909 C C   . LEU   A 1 235 ? 140.145 141.614 126.135 1.00 49.56  ? 261 LEU   A C   1 
ATOM   1910 O O   . LEU   A 1 235 ? 138.933 141.519 126.343 1.00 54.94  ? 261 LEU   A O   1 
ATOM   1911 C CB  . LEU   A 1 235 ? 140.864 141.909 123.758 1.00 49.07  ? 261 LEU   A CB  1 
ATOM   1912 C CG  . LEU   A 1 235 ? 141.218 142.813 122.576 1.00 56.14  ? 261 LEU   A CG  1 
ATOM   1913 C CD1 . LEU   A 1 235 ? 141.579 141.973 121.361 1.00 57.10  ? 261 LEU   A CD1 1 
ATOM   1914 C CD2 . LEU   A 1 235 ? 140.078 143.765 122.246 1.00 53.99  ? 261 LEU   A CD2 1 
ATOM   1915 N N   . LEU   A 1 236 ? 141.037 140.872 126.792 1.00 50.82  ? 262 LEU   A N   1 
ATOM   1916 C CA  . LEU   A 1 236 ? 140.592 139.938 127.813 1.00 49.00  ? 262 LEU   A CA  1 
ATOM   1917 C C   . LEU   A 1 236 ? 139.980 140.671 128.991 1.00 49.23  ? 262 LEU   A C   1 
ATOM   1918 O O   . LEU   A 1 236 ? 138.978 140.221 129.539 1.00 53.75  ? 262 LEU   A O   1 
ATOM   1919 C CB  . LEU   A 1 236 ? 141.748 139.054 128.273 1.00 51.61  ? 262 LEU   A CB  1 
ATOM   1920 C CG  . LEU   A 1 236 ? 141.318 137.800 129.047 1.00 54.59  ? 262 LEU   A CG  1 
ATOM   1921 C CD1 . LEU   A 1 236 ? 142.297 136.671 128.783 1.00 59.11  ? 262 LEU   A CD1 1 
ATOM   1922 C CD2 . LEU   A 1 236 ? 141.180 138.044 130.549 1.00 55.23  ? 262 LEU   A CD2 1 
ATOM   1923 N N   . ASP   A 1 237 ? 140.552 141.808 129.386 1.00 48.53  ? 263 ASP   A N   1 
ATOM   1924 C CA  . ASP   A 1 237 ? 139.969 142.562 130.492 1.00 48.95  ? 263 ASP   A CA  1 
ATOM   1925 C C   . ASP   A 1 237 ? 138.548 142.995 130.163 1.00 51.94  ? 263 ASP   A C   1 
ATOM   1926 O O   . ASP   A 1 237 ? 137.602 142.684 130.902 1.00 60.36  ? 263 ASP   A O   1 
ATOM   1927 C CB  . ASP   A 1 237 ? 140.832 143.780 130.825 1.00 48.25  ? 263 ASP   A CB  1 
ATOM   1928 C CG  . ASP   A 1 237 ? 142.074 143.420 131.612 1.00 57.85  ? 263 ASP   A CG  1 
ATOM   1929 O OD1 . ASP   A 1 237 ? 142.351 142.215 131.780 1.00 62.18  ? 263 ASP   A OD1 1 
ATOM   1930 O OD2 . ASP   A 1 237 ? 142.776 144.346 132.067 1.00 62.97  ? 263 ASP   A OD2 1 
ATOM   1931 N N   . LEU   A 1 238 ? 138.364 143.662 129.021 1.00 46.40  ? 264 LEU   A N   1 
ATOM   1932 C CA  . LEU   A 1 238 ? 137.026 144.157 128.686 1.00 51.10  ? 264 LEU   A CA  1 
ATOM   1933 C C   . LEU   A 1 238 ? 136.041 143.005 128.445 1.00 53.25  ? 264 LEU   A C   1 
ATOM   1934 O O   . LEU   A 1 238 ? 134.912 143.003 128.969 1.00 50.93  ? 264 LEU   A O   1 
ATOM   1935 C CB  . LEU   A 1 238 ? 137.111 145.081 127.470 1.00 47.81  ? 264 LEU   A CB  1 
ATOM   1936 C CG  . LEU   A 1 238 ? 138.090 146.256 127.593 1.00 43.58  ? 264 LEU   A CG  1 
ATOM   1937 C CD1 . LEU   A 1 238 ? 138.113 147.075 126.323 1.00 40.12  ? 264 LEU   A CD1 1 
ATOM   1938 C CD2 . LEU   A 1 238 ? 137.744 147.144 128.779 1.00 48.00  ? 264 LEU   A CD2 1 
ATOM   1939 N N   . SER   A 1 239 ? 136.463 141.997 127.680 1.00 50.48  ? 265 SER   A N   1 
ATOM   1940 C CA  . SER   A 1 239 ? 135.576 140.894 127.345 1.00 48.55  ? 265 SER   A CA  1 
ATOM   1941 C C   . SER   A 1 239 ? 135.271 140.028 128.560 1.00 51.21  ? 265 SER   A C   1 
ATOM   1942 O O   . SER   A 1 239 ? 134.165 139.504 128.679 1.00 55.81  ? 265 SER   A O   1 
ATOM   1943 C CB  . SER   A 1 239 ? 136.192 140.052 126.230 1.00 52.70  ? 265 SER   A CB  1 
ATOM   1944 O OG  . SER   A 1 239 ? 137.423 139.484 126.638 1.00 55.82  ? 265 SER   A OG  1 
ATOM   1945 N N   . ALA   A 1 240 ? 136.235 139.826 129.458 1.00 48.49  ? 266 ALA   A N   1 
ATOM   1946 C CA  . ALA   A 1 240 ? 135.958 139.058 130.661 1.00 49.11  ? 266 ALA   A CA  1 
ATOM   1947 C C   . ALA   A 1 240 ? 135.068 139.838 131.607 1.00 52.18  ? 266 ALA   A C   1 
ATOM   1948 O O   . ALA   A 1 240 ? 134.325 139.239 132.392 1.00 53.68  ? 266 ALA   A O   1 
ATOM   1949 C CB  . ALA   A 1 240 ? 137.262 138.677 131.358 1.00 50.76  ? 266 ALA   A CB  1 
ATOM   1950 N N   . GLY   A 1 241 ? 135.130 141.169 131.558 1.00 50.95  ? 267 GLY   A N   1 
ATOM   1951 C CA  . GLY   A 1 241 ? 134.144 141.949 132.278 1.00 51.33  ? 267 GLY   A CA  1 
ATOM   1952 C C   . GLY   A 1 241 ? 132.737 141.676 131.786 1.00 51.62  ? 267 GLY   A C   1 
ATOM   1953 O O   . GLY   A 1 241 ? 131.838 141.390 132.578 1.00 41.93  ? 267 GLY   A O   1 
ATOM   1954 N N   . PHE   A 1 242 ? 132.537 141.715 130.464 1.00 57.63  ? 268 PHE   A N   1 
ATOM   1955 C CA  . PHE   A 1 242 ? 131.166 141.626 129.951 1.00 51.43  ? 268 PHE   A CA  1 
ATOM   1956 C C   . PHE   A 1 242 ? 130.652 140.189 129.852 1.00 46.17  ? 268 PHE   A C   1 
ATOM   1957 O O   . PHE   A 1 242 ? 129.495 139.922 130.188 1.00 49.19  ? 268 PHE   A O   1 
ATOM   1958 C CB  . PHE   A 1 242 ? 131.066 142.307 128.588 1.00 50.27  ? 268 PHE   A CB  1 
ATOM   1959 C CG  . PHE   A 1 242 ? 131.046 143.803 128.665 1.00 54.64  ? 268 PHE   A CG  1 
ATOM   1960 C CD1 . PHE   A 1 242 ? 129.921 144.470 129.111 1.00 54.04  ? 268 PHE   A CD1 1 
ATOM   1961 C CD2 . PHE   A 1 242 ? 132.153 144.543 128.293 1.00 58.72  ? 268 PHE   A CD2 1 
ATOM   1962 C CE1 . PHE   A 1 242 ? 129.897 145.844 129.186 1.00 55.99  ? 268 PHE   A CE1 1 
ATOM   1963 C CE2 . PHE   A 1 242 ? 132.136 145.921 128.364 1.00 61.53  ? 268 PHE   A CE2 1 
ATOM   1964 C CZ  . PHE   A 1 242 ? 131.006 146.572 128.811 1.00 60.08  ? 268 PHE   A CZ  1 
ATOM   1965 N N   . LEU   A 1 243 ? 131.491 139.255 129.402 1.00 46.77  ? 269 LEU   A N   1 
ATOM   1966 C CA  . LEU   A 1 243 ? 131.017 137.942 128.967 1.00 48.53  ? 269 LEU   A CA  1 
ATOM   1967 C C   . LEU   A 1 243 ? 130.467 137.107 130.117 1.00 53.26  ? 269 LEU   A C   1 
ATOM   1968 O O   . LEU   A 1 243 ? 129.449 136.425 129.953 1.00 57.30  ? 269 LEU   A O   1 
ATOM   1969 C CB  . LEU   A 1 243 ? 132.150 137.183 128.274 1.00 48.12  ? 269 LEU   A CB  1 
ATOM   1970 C CG  . LEU   A 1 243 ? 132.613 137.655 126.891 1.00 52.97  ? 269 LEU   A CG  1 
ATOM   1971 C CD1 . LEU   A 1 243 ? 133.945 137.007 126.559 1.00 51.14  ? 269 LEU   A CD1 1 
ATOM   1972 C CD2 . LEU   A 1 243 ? 131.598 137.352 125.797 1.00 52.94  ? 269 LEU   A CD2 1 
ATOM   1973 N N   . LEU   A 1 244 ? 131.132 137.125 131.275 1.00 47.80  ? 270 LEU   A N   1 
ATOM   1974 C CA  . LEU   A 1 244 ? 130.763 136.215 132.359 1.00 45.07  ? 270 LEU   A CA  1 
ATOM   1975 C C   . LEU   A 1 244 ? 129.335 136.440 132.834 1.00 46.25  ? 270 LEU   A C   1 
ATOM   1976 O O   . LEU   A 1 244 ? 128.679 135.501 133.296 1.00 50.30  ? 270 LEU   A O   1 
ATOM   1977 C CB  . LEU   A 1 244 ? 131.728 136.371 133.536 1.00 45.47  ? 270 LEU   A CB  1 
ATOM   1978 C CG  . LEU   A 1 244 ? 133.133 135.784 133.400 1.00 49.90  ? 270 LEU   A CG  1 
ATOM   1979 C CD1 . LEU   A 1 244 ? 133.989 136.217 134.571 1.00 50.62  ? 270 LEU   A CD1 1 
ATOM   1980 C CD2 . LEU   A 1 244 ? 133.094 134.269 133.309 1.00 53.33  ? 270 LEU   A CD2 1 
ATOM   1981 N N   . PHE   A 1 245 ? 128.841 137.672 132.740 1.00 43.73  ? 271 PHE   A N   1 
ATOM   1982 C CA  . PHE   A 1 245 ? 127.493 137.969 133.207 1.00 47.67  ? 271 PHE   A CA  1 
ATOM   1983 C C   . PHE   A 1 245 ? 126.442 137.229 132.388 1.00 51.38  ? 271 PHE   A C   1 
ATOM   1984 O O   . PHE   A 1 245 ? 125.498 136.661 132.949 1.00 54.27  ? 271 PHE   A O   1 
ATOM   1985 C CB  . PHE   A 1 245 ? 127.263 139.477 133.160 1.00 47.81  ? 271 PHE   A CB  1 
ATOM   1986 C CG  . PHE   A 1 245 ? 125.851 139.888 133.438 1.00 47.81  ? 271 PHE   A CG  1 
ATOM   1987 C CD1 . PHE   A 1 245 ? 125.213 139.491 134.593 1.00 47.78  ? 271 PHE   A CD1 1 
ATOM   1988 C CD2 . PHE   A 1 245 ? 125.170 140.695 132.547 1.00 49.74  ? 271 PHE   A CD2 1 
ATOM   1989 C CE1 . PHE   A 1 245 ? 123.920 139.880 134.848 1.00 49.69  ? 271 PHE   A CE1 1 
ATOM   1990 C CE2 . PHE   A 1 245 ? 123.878 141.086 132.798 1.00 51.36  ? 271 PHE   A CE2 1 
ATOM   1991 C CZ  . PHE   A 1 245 ? 123.251 140.679 133.950 1.00 49.40  ? 271 PHE   A CZ  1 
ATOM   1992 N N   . PHE   A 1 246 ? 126.586 137.222 131.066 1.00 46.41  ? 272 PHE   A N   1 
ATOM   1993 C CA  . PHE   A 1 246 ? 125.589 136.612 130.199 1.00 45.17  ? 272 PHE   A CA  1 
ATOM   1994 C C   . PHE   A 1 246 ? 125.684 135.093 130.236 1.00 49.34  ? 272 PHE   A C   1 
ATOM   1995 O O   . PHE   A 1 246 ? 126.767 134.525 130.396 1.00 52.09  ? 272 PHE   A O   1 
ATOM   1996 C CB  . PHE   A 1 246 ? 125.755 137.116 128.769 1.00 44.26  ? 272 PHE   A CB  1 
ATOM   1997 C CG  . PHE   A 1 246 ? 125.466 138.576 128.610 1.00 41.57  ? 272 PHE   A CG  1 
ATOM   1998 C CD1 . PHE   A 1 246 ? 124.172 139.048 128.675 1.00 41.10  ? 272 PHE   A CD1 1 
ATOM   1999 C CD2 . PHE   A 1 246 ? 126.486 139.477 128.391 1.00 45.61  ? 272 PHE   A CD2 1 
ATOM   2000 C CE1 . PHE   A 1 246 ? 123.900 140.384 128.529 1.00 41.21  ? 272 PHE   A CE1 1 
ATOM   2001 C CE2 . PHE   A 1 246 ? 126.219 140.819 128.245 1.00 48.92  ? 272 PHE   A CE2 1 
ATOM   2002 C CZ  . PHE   A 1 246 ? 124.922 141.271 128.314 1.00 45.94  ? 272 PHE   A CZ  1 
ATOM   2003 N N   . ASP   A 1 247 ? 124.530 134.436 130.090 1.00 47.93  ? 273 ASP   A N   1 
ATOM   2004 C CA  . ASP   A 1 247 ? 124.482 132.978 130.164 1.00 48.19  ? 273 ASP   A CA  1 
ATOM   2005 C C   . ASP   A 1 247 ? 125.253 132.329 129.024 1.00 44.88  ? 273 ASP   A C   1 
ATOM   2006 O O   . ASP   A 1 247 ? 125.949 131.329 129.230 1.00 42.91  ? 273 ASP   A O   1 
ATOM   2007 C CB  . ASP   A 1 247 ? 123.033 132.495 130.145 1.00 48.89  ? 273 ASP   A CB  1 
ATOM   2008 C CG  . ASP   A 1 247 ? 122.277 132.859 131.401 1.00 56.79  ? 273 ASP   A CG  1 
ATOM   2009 O OD1 . ASP   A 1 247 ? 122.892 132.877 132.489 1.00 61.11  ? 273 ASP   A OD1 1 
ATOM   2010 O OD2 . ASP   A 1 247 ? 121.060 133.123 131.301 1.00 59.37  ? 273 ASP   A OD2 1 
ATOM   2011 N N   . VAL   A 1 248 ? 125.135 132.877 127.816 1.00 44.46  ? 274 VAL   A N   1 
ATOM   2012 C CA  . VAL   A 1 248 ? 125.662 132.193 126.640 1.00 44.08  ? 274 VAL   A CA  1 
ATOM   2013 C C   . VAL   A 1 248 ? 127.184 132.160 126.674 1.00 52.98  ? 274 VAL   A C   1 
ATOM   2014 O O   . VAL   A 1 248 ? 127.806 131.175 126.258 1.00 57.57  ? 274 VAL   A O   1 
ATOM   2015 C CB  . VAL   A 1 248 ? 125.136 132.859 125.355 1.00 38.53  ? 274 VAL   A CB  1 
ATOM   2016 C CG1 . VAL   A 1 248 ? 125.554 132.054 124.128 1.00 44.16  ? 274 VAL   A CG1 1 
ATOM   2017 C CG2 . VAL   A 1 248 ? 123.622 133.005 125.409 1.00 40.20  ? 274 VAL   A CG2 1 
ATOM   2018 N N   . SER   A 1 249 ? 127.807 133.226 127.169 1.00 49.82  ? 275 SER   A N   1 
ATOM   2019 C CA  . SER   A 1 249 ? 129.249 133.402 127.087 1.00 46.39  ? 275 SER   A CA  1 
ATOM   2020 C C   . SER   A 1 249 ? 130.000 132.894 128.311 1.00 45.13  ? 275 SER   A C   1 
ATOM   2021 O O   . SER   A 1 249 ? 131.216 133.093 128.393 1.00 54.75  ? 275 SER   A O   1 
ATOM   2022 C CB  . SER   A 1 249 ? 129.570 134.879 126.879 1.00 48.99  ? 275 SER   A CB  1 
ATOM   2023 O OG  . SER   A 1 249 ? 128.902 135.385 125.738 1.00 54.59  ? 275 SER   A OG  1 
ATOM   2024 N N   . ARG   A 1 250 ? 129.321 132.253 129.261 1.00 42.71  ? 276 ARG   A N   1 
ATOM   2025 C CA  . ARG   A 1 250 ? 129.953 131.978 130.546 1.00 47.19  ? 276 ARG   A CA  1 
ATOM   2026 C C   . ARG   A 1 250 ? 131.065 130.943 130.423 1.00 48.70  ? 276 ARG   A C   1 
ATOM   2027 O O   . ARG   A 1 250 ? 132.083 131.044 131.113 1.00 52.12  ? 276 ARG   A O   1 
ATOM   2028 C CB  . ARG   A 1 250 ? 128.908 131.521 131.559 1.00 47.13  ? 276 ARG   A CB  1 
ATOM   2029 C CG  . ARG   A 1 250 ? 129.437 131.498 132.973 1.00 47.25  ? 276 ARG   A CG  1 
ATOM   2030 C CD  . ARG   A 1 250 ? 128.364 131.214 133.995 1.00 49.74  ? 276 ARG   A CD  1 
ATOM   2031 N NE  . ARG   A 1 250 ? 127.386 132.294 134.090 1.00 47.96  ? 276 ARG   A NE  1 
ATOM   2032 C CZ  . ARG   A 1 250 ? 126.133 132.261 133.650 1.00 49.47  ? 276 ARG   A CZ  1 
ATOM   2033 N NH1 . ARG   A 1 250 ? 125.626 131.197 133.044 1.00 53.03  ? 276 ARG   A NH1 1 
ATOM   2034 N NH2 . ARG   A 1 250 ? 125.361 133.327 133.828 1.00 49.44  ? 276 ARG   A NH2 1 
ATOM   2035 N N   . SER   A 1 251 ? 130.893 129.939 129.565 1.00 44.15  ? 277 SER   A N   1 
ATOM   2036 C CA  . SER   A 1 251 ? 131.887 128.872 129.482 1.00 45.51  ? 277 SER   A CA  1 
ATOM   2037 C C   . SER   A 1 251 ? 133.199 129.377 128.888 1.00 51.50  ? 277 SER   A C   1 
ATOM   2038 O O   . SER   A 1 251 ? 134.280 129.151 129.451 1.00 56.66  ? 277 SER   A O   1 
ATOM   2039 C CB  . SER   A 1 251 ? 131.331 127.716 128.655 1.00 47.95  ? 277 SER   A CB  1 
ATOM   2040 O OG  . SER   A 1 251 ? 130.958 128.152 127.361 1.00 53.51  ? 277 SER   A OG  1 
ATOM   2041 N N   . ILE   A 1 252 ? 133.122 130.074 127.754 1.00 50.37  ? 278 ILE   A N   1 
ATOM   2042 C CA  . ILE   A 1 252 ? 134.326 130.591 127.113 1.00 51.90  ? 278 ILE   A CA  1 
ATOM   2043 C C   . ILE   A 1 252 ? 134.986 131.638 127.999 1.00 54.57  ? 278 ILE   A C   1 
ATOM   2044 O O   . ILE   A 1 252 ? 136.219 131.686 128.121 1.00 58.30  ? 278 ILE   A O   1 
ATOM   2045 C CB  . ILE   A 1 252 ? 133.985 131.159 125.722 1.00 55.55  ? 278 ILE   A CB  1 
ATOM   2046 C CG1 . ILE   A 1 252 ? 133.365 130.083 124.812 1.00 58.45  ? 278 ILE   A CG1 1 
ATOM   2047 C CG2 . ILE   A 1 252 ? 135.219 131.770 125.079 1.00 57.72  ? 278 ILE   A CG2 1 
ATOM   2048 C CD1 . ILE   A 1 252 ? 134.245 128.864 124.534 1.00 57.15  ? 278 ILE   A CD1 1 
ATOM   2049 N N   . GLY   A 1 253 ? 134.178 132.499 128.620 1.00 50.13  ? 279 GLY   A N   1 
ATOM   2050 C CA  . GLY   A 1 253 ? 134.725 133.480 129.538 1.00 48.30  ? 279 GLY   A CA  1 
ATOM   2051 C C   . GLY   A 1 253 ? 135.438 132.838 130.711 1.00 49.89  ? 279 GLY   A C   1 
ATOM   2052 O O   . GLY   A 1 253 ? 136.522 133.273 131.100 1.00 57.65  ? 279 GLY   A O   1 
ATOM   2053 N N   . LEU   A 1 254 ? 134.846 131.786 131.282 1.00 44.79  ? 280 LEU   A N   1 
ATOM   2054 C CA  . LEU   A 1 254 ? 135.485 131.092 132.394 1.00 45.31  ? 280 LEU   A CA  1 
ATOM   2055 C C   . LEU   A 1 254 ? 136.806 130.473 131.967 1.00 48.74  ? 280 LEU   A C   1 
ATOM   2056 O O   . LEU   A 1 254 ? 137.803 130.563 132.693 1.00 56.06  ? 280 LEU   A O   1 
ATOM   2057 C CB  . LEU   A 1 254 ? 134.557 130.016 132.956 1.00 43.39  ? 280 LEU   A CB  1 
ATOM   2058 C CG  . LEU   A 1 254 ? 133.473 130.442 133.951 1.00 45.78  ? 280 LEU   A CG  1 
ATOM   2059 C CD1 . LEU   A 1 254 ? 132.530 129.289 134.224 1.00 44.15  ? 280 LEU   A CD1 1 
ATOM   2060 C CD2 . LEU   A 1 254 ? 134.074 130.939 135.252 1.00 47.81  ? 280 LEU   A CD2 1 
ATOM   2061 N N   . PHE   A 1 255 ? 136.839 129.852 130.786 1.00 47.76  ? 281 PHE   A N   1 
ATOM   2062 C CA  . PHE   A 1 255 ? 138.077 129.235 130.318 1.00 50.21  ? 281 PHE   A CA  1 
ATOM   2063 C C   . PHE   A 1 255 ? 139.176 130.275 130.125 1.00 52.75  ? 281 PHE   A C   1 
ATOM   2064 O O   . PHE   A 1 255 ? 140.303 130.106 130.613 1.00 55.43  ? 281 PHE   A O   1 
ATOM   2065 C CB  . PHE   A 1 255 ? 137.822 128.477 129.018 1.00 55.33  ? 281 PHE   A CB  1 
ATOM   2066 C CG  . PHE   A 1 255 ? 139.059 127.880 128.415 1.00 60.56  ? 281 PHE   A CG  1 
ATOM   2067 C CD1 . PHE   A 1 255 ? 139.626 126.741 128.954 1.00 63.53  ? 281 PHE   A CD1 1 
ATOM   2068 C CD2 . PHE   A 1 255 ? 139.650 128.455 127.305 1.00 60.73  ? 281 PHE   A CD2 1 
ATOM   2069 C CE1 . PHE   A 1 255 ? 140.763 126.188 128.401 1.00 66.09  ? 281 PHE   A CE1 1 
ATOM   2070 C CE2 . PHE   A 1 255 ? 140.787 127.907 126.748 1.00 62.35  ? 281 PHE   A CE2 1 
ATOM   2071 C CZ  . PHE   A 1 255 ? 141.344 126.772 127.296 1.00 63.96  ? 281 PHE   A CZ  1 
ATOM   2072 N N   . PHE   A 1 256 ? 138.864 131.366 129.419 1.00 51.14  ? 282 PHE   A N   1 
ATOM   2073 C CA  . PHE   A 1 256 ? 139.872 132.396 129.187 1.00 52.49  ? 282 PHE   A CA  1 
ATOM   2074 C C   . PHE   A 1 256 ? 140.321 133.039 130.490 1.00 52.56  ? 282 PHE   A C   1 
ATOM   2075 O O   . PHE   A 1 256 ? 141.515 133.292 130.679 1.00 57.96  ? 282 PHE   A O   1 
ATOM   2076 C CB  . PHE   A 1 256 ? 139.340 133.470 128.230 1.00 53.35  ? 282 PHE   A CB  1 
ATOM   2077 C CG  . PHE   A 1 256 ? 139.167 133.018 126.789 1.00 57.84  ? 282 PHE   A CG  1 
ATOM   2078 C CD1 . PHE   A 1 256 ? 139.874 131.948 126.255 1.00 57.18  ? 282 PHE   A CD1 1 
ATOM   2079 C CD2 . PHE   A 1 256 ? 138.294 133.700 125.961 1.00 60.48  ? 282 PHE   A CD2 1 
ATOM   2080 C CE1 . PHE   A 1 256 ? 139.700 131.568 124.941 1.00 60.29  ? 282 PHE   A CE1 1 
ATOM   2081 C CE2 . PHE   A 1 256 ? 138.120 133.321 124.645 1.00 60.70  ? 282 PHE   A CE2 1 
ATOM   2082 C CZ  . PHE   A 1 256 ? 138.823 132.255 124.137 1.00 61.49  ? 282 PHE   A CZ  1 
ATOM   2083 N N   . VAL   A 1 257 ? 139.389 133.313 131.402 1.00 46.55  ? 283 VAL   A N   1 
ATOM   2084 C CA  . VAL   A 1 257 ? 139.751 133.953 132.661 1.00 43.81  ? 283 VAL   A CA  1 
ATOM   2085 C C   . VAL   A 1 257 ? 140.636 133.035 133.497 1.00 51.44  ? 283 VAL   A C   1 
ATOM   2086 O O   . VAL   A 1 257 ? 141.610 133.485 134.112 1.00 56.12  ? 283 VAL   A O   1 
ATOM   2087 C CB  . VAL   A 1 257 ? 138.479 134.375 133.417 1.00 46.55  ? 283 VAL   A CB  1 
ATOM   2088 C CG1 . VAL   A 1 257 ? 138.806 134.813 134.828 1.00 53.82  ? 283 VAL   A CG1 1 
ATOM   2089 C CG2 . VAL   A 1 257 ? 137.789 135.509 132.692 1.00 50.55  ? 283 VAL   A CG2 1 
ATOM   2090 N N   . SER   A 1 258 ? 140.316 131.740 133.541 1.00 51.18  ? 284 SER   A N   1 
ATOM   2091 C CA  . SER   A 1 258 ? 141.134 130.808 134.310 1.00 49.82  ? 284 SER   A CA  1 
ATOM   2092 C C   . SER   A 1 258 ? 142.534 130.691 133.725 1.00 53.64  ? 284 SER   A C   1 
ATOM   2093 O O   . SER   A 1 258 ? 143.525 130.677 134.468 1.00 60.74  ? 284 SER   A O   1 
ATOM   2094 C CB  . SER   A 1 258 ? 140.462 129.439 134.361 1.00 51.92  ? 284 SER   A CB  1 
ATOM   2095 O OG  . SER   A 1 258 ? 139.247 129.499 135.087 1.00 58.26  ? 284 SER   A OG  1 
ATOM   2096 N N   . TYR   A 1 259 ? 142.641 130.607 132.397 1.00 52.27  ? 285 TYR   A N   1 
ATOM   2097 C CA  . TYR   A 1 259 ? 143.960 130.560 131.774 1.00 54.45  ? 285 TYR   A CA  1 
ATOM   2098 C C   . TYR   A 1 259 ? 144.741 131.836 132.056 1.00 55.12  ? 285 TYR   A C   1 
ATOM   2099 O O   . TYR   A 1 259 ? 145.936 131.790 132.381 1.00 59.83  ? 285 TYR   A O   1 
ATOM   2100 C CB  . TYR   A 1 259 ? 143.811 130.341 130.271 1.00 56.70  ? 285 TYR   A CB  1 
ATOM   2101 C CG  . TYR   A 1 259 ? 145.110 130.140 129.533 1.00 58.94  ? 285 TYR   A CG  1 
ATOM   2102 C CD1 . TYR   A 1 259 ? 145.875 129.003 129.734 1.00 61.47  ? 285 TYR   A CD1 1 
ATOM   2103 C CD2 . TYR   A 1 259 ? 145.555 131.073 128.615 1.00 62.60  ? 285 TYR   A CD2 1 
ATOM   2104 C CE1 . TYR   A 1 259 ? 147.057 128.811 129.055 1.00 69.25  ? 285 TYR   A CE1 1 
ATOM   2105 C CE2 . TYR   A 1 259 ? 146.736 130.891 127.930 1.00 69.10  ? 285 TYR   A CE2 1 
ATOM   2106 C CZ  . TYR   A 1 259 ? 147.483 129.757 128.153 1.00 72.13  ? 285 TYR   A CZ  1 
ATOM   2107 O OH  . TYR   A 1 259 ? 148.663 129.566 127.471 1.00 74.97  ? 285 TYR   A OH  1 
ATOM   2108 N N   . PHE   A 1 260 ? 144.068 132.982 131.956 1.00 52.34  ? 286 PHE   A N   1 
ATOM   2109 C CA  . PHE   A 1 260 ? 144.689 134.271 132.225 1.00 52.68  ? 286 PHE   A CA  1 
ATOM   2110 C C   . PHE   A 1 260 ? 145.228 134.336 133.646 1.00 52.93  ? 286 PHE   A C   1 
ATOM   2111 O O   . PHE   A 1 260 ? 146.357 134.783 133.870 1.00 58.43  ? 286 PHE   A O   1 
ATOM   2112 C CB  . PHE   A 1 260 ? 143.647 135.361 131.966 1.00 55.51  ? 286 PHE   A CB  1 
ATOM   2113 C CG  . PHE   A 1 260 ? 144.065 136.744 132.365 1.00 54.01  ? 286 PHE   A CG  1 
ATOM   2114 C CD1 . PHE   A 1 260 ? 144.750 137.552 131.484 1.00 59.43  ? 286 PHE   A CD1 1 
ATOM   2115 C CD2 . PHE   A 1 260 ? 143.713 137.259 133.597 1.00 56.34  ? 286 PHE   A CD2 1 
ATOM   2116 C CE1 . PHE   A 1 260 ? 145.109 138.828 131.839 1.00 59.75  ? 286 PHE   A CE1 1 
ATOM   2117 C CE2 . PHE   A 1 260 ? 144.074 138.533 133.955 1.00 58.31  ? 286 PHE   A CE2 1 
ATOM   2118 C CZ  . PHE   A 1 260 ? 144.770 139.319 133.072 1.00 58.26  ? 286 PHE   A CZ  1 
ATOM   2119 N N   . HIS   A 1 261 ? 144.453 133.853 134.615 1.00 50.72  ? 287 HIS   A N   1 
ATOM   2120 C CA  . HIS   A 1 261 ? 144.872 133.968 136.006 1.00 50.44  ? 287 HIS   A CA  1 
ATOM   2121 C C   . HIS   A 1 261 ? 145.954 132.958 136.363 1.00 52.32  ? 287 HIS   A C   1 
ATOM   2122 O O   . HIS   A 1 261 ? 146.847 133.268 137.156 1.00 57.43  ? 287 HIS   A O   1 
ATOM   2123 C CB  . HIS   A 1 261 ? 143.667 133.817 136.930 1.00 53.09  ? 287 HIS   A CB  1 
ATOM   2124 C CG  . HIS   A 1 261 ? 142.807 135.038 136.996 1.00 49.11  ? 287 HIS   A CG  1 
ATOM   2125 N ND1 . HIS   A 1 261 ? 143.318 136.296 137.225 1.00 49.93  ? 287 HIS   A ND1 1 
ATOM   2126 C CD2 . HIS   A 1 261 ? 141.469 135.193 136.874 1.00 48.88  ? 287 HIS   A CD2 1 
ATOM   2127 C CE1 . HIS   A 1 261 ? 142.333 137.175 137.228 1.00 53.86  ? 287 HIS   A CE1 1 
ATOM   2128 N NE2 . HIS   A 1 261 ? 141.201 136.531 137.018 1.00 51.46  ? 287 HIS   A NE2 1 
ATOM   2129 N N   . CYS   A 1 262 ? 145.911 131.752 135.793 1.00 53.40  ? 288 CYS   A N   1 
ATOM   2130 C CA  . CYS   A 1 262 ? 147.006 130.812 136.022 1.00 57.27  ? 288 CYS   A CA  1 
ATOM   2131 C C   . CYS   A 1 262 ? 148.308 131.333 135.423 1.00 59.22  ? 288 CYS   A C   1 
ATOM   2132 O O   . CYS   A 1 262 ? 149.378 131.236 136.046 1.00 61.40  ? 288 CYS   A O   1 
ATOM   2133 C CB  . CYS   A 1 262 ? 146.652 129.444 135.444 1.00 56.56  ? 288 CYS   A CB  1 
ATOM   2134 S SG  . CYS   A 1 262 ? 145.340 128.590 136.341 1.00 63.49  ? 288 CYS   A SG  1 
ATOM   2135 N N   . MET   A 1 263 ? 148.239 131.909 134.220 1.00 58.97  ? 289 MET   A N   1 
ATOM   2136 C CA  . MET   A 1 263 ? 149.434 132.497 133.628 1.00 57.70  ? 289 MET   A CA  1 
ATOM   2137 C C   . MET   A 1 263 ? 149.923 133.688 134.441 1.00 56.24  ? 289 MET   A C   1 
ATOM   2138 O O   . MET   A 1 263 ? 151.131 133.901 134.566 1.00 60.63  ? 289 MET   A O   1 
ATOM   2139 C CB  . MET   A 1 263 ? 149.169 132.906 132.179 1.00 59.02  ? 289 MET   A CB  1 
ATOM   2140 C CG  . MET   A 1 263 ? 149.727 131.927 131.166 1.00 62.08  ? 289 MET   A CG  1 
ATOM   2141 S SD  . MET   A 1 263 ? 149.559 132.512 129.477 1.00 79.09  ? 289 MET   A SD  1 
ATOM   2142 C CE  . MET   A 1 263 ? 150.693 131.417 128.631 1.00 69.95  ? 289 MET   A CE  1 
ATOM   2143 N N   . ASN   A 1 264 ? 149.007 134.487 134.989 1.00 55.57  ? 290 ASN   A N   1 
ATOM   2144 C CA  . ASN   A 1 264 ? 149.429 135.588 135.848 1.00 52.83  ? 290 ASN   A CA  1 
ATOM   2145 C C   . ASN   A 1 264 ? 150.105 135.074 137.109 1.00 55.84  ? 290 ASN   A C   1 
ATOM   2146 O O   . ASN   A 1 264 ? 151.090 135.655 137.576 1.00 59.17  ? 290 ASN   A O   1 
ATOM   2147 C CB  . ASN   A 1 264 ? 148.234 136.462 136.211 1.00 53.47  ? 290 ASN   A CB  1 
ATOM   2148 C CG  . ASN   A 1 264 ? 147.852 137.406 135.105 1.00 58.69  ? 290 ASN   A CG  1 
ATOM   2149 O OD1 . ASN   A 1 264 ? 148.300 137.267 133.969 1.00 59.36  ? 290 ASN   A OD1 1 
ATOM   2150 N ND2 . ASN   A 1 264 ? 147.014 138.380 135.429 1.00 62.77  ? 290 ASN   A ND2 1 
ATOM   2151 N N   . SER   A 1 265 ? 149.580 133.991 137.682 1.00 55.51  ? 291 SER   A N   1 
ATOM   2152 C CA  . SER   A 1 265 ? 150.180 133.428 138.884 1.00 55.79  ? 291 SER   A CA  1 
ATOM   2153 C C   . SER   A 1 265 ? 151.593 132.941 138.615 1.00 59.69  ? 291 SER   A C   1 
ATOM   2154 O O   . SER   A 1 265 ? 152.503 133.179 139.418 1.00 63.94  ? 291 SER   A O   1 
ATOM   2155 C CB  . SER   A 1 265 ? 149.317 132.285 139.412 1.00 59.51  ? 291 SER   A CB  1 
ATOM   2156 O OG  . SER   A 1 265 ? 149.949 131.631 140.498 1.00 66.66  ? 291 SER   A OG  1 
ATOM   2157 N N   . GLN   A 1 266 ? 151.802 132.262 137.487 1.00 61.71  ? 292 GLN   A N   1 
ATOM   2158 C CA  . GLN   A 1 266 ? 153.133 131.728 137.210 1.00 61.01  ? 292 GLN   A CA  1 
ATOM   2159 C C   . GLN   A 1 266 ? 154.102 132.806 136.736 1.00 59.08  ? 292 GLN   A C   1 
ATOM   2160 O O   . GLN   A 1 266 ? 155.274 132.798 137.125 1.00 60.25  ? 292 GLN   A O   1 
ATOM   2161 C CB  . GLN   A 1 266 ? 153.043 130.606 136.175 1.00 66.09  ? 292 GLN   A CB  1 
ATOM   2162 C CG  . GLN   A 1 266 ? 152.348 129.348 136.679 1.00 70.55  ? 292 GLN   A CG  1 
ATOM   2163 C CD  . GLN   A 1 266 ? 153.118 128.655 137.788 1.00 73.82  ? 292 GLN   A CD  1 
ATOM   2164 O OE1 . GLN   A 1 266 ? 154.255 129.016 138.089 1.00 65.81  ? 292 GLN   A OE1 1 
ATOM   2165 N NE2 . GLN   A 1 266 ? 152.499 127.655 138.404 1.00 78.20  ? 292 GLN   A NE2 1 
ATOM   2166 N N   . LEU   A 1 267 ? 153.640 133.743 135.907 1.00 58.05  ? 293 LEU   A N   1 
ATOM   2167 C CA  . LEU   A 1 267 ? 154.547 134.724 135.319 1.00 56.68  ? 293 LEU   A CA  1 
ATOM   2168 C C   . LEU   A 1 267 ? 155.007 135.751 136.345 1.00 57.40  ? 293 LEU   A C   1 
ATOM   2169 O O   . LEU   A 1 267 ? 156.198 136.075 136.410 1.00 61.13  ? 293 LEU   A O   1 
ATOM   2170 C CB  . LEU   A 1 267 ? 153.870 135.428 134.142 1.00 55.92  ? 293 LEU   A CB  1 
ATOM   2171 C CG  . LEU   A 1 267 ? 153.625 134.630 132.862 1.00 59.63  ? 293 LEU   A CG  1 
ATOM   2172 C CD1 . LEU   A 1 267 ? 152.832 135.466 131.880 1.00 60.95  ? 293 LEU   A CD1 1 
ATOM   2173 C CD2 . LEU   A 1 267 ? 154.926 134.181 132.235 1.00 64.19  ? 293 LEU   A CD2 1 
ATOM   2174 N N   . PHE   A 1 268 ? 154.087 136.273 137.147 1.00 55.07  ? 294 PHE   A N   1 
ATOM   2175 C CA  . PHE   A 1 268 ? 154.375 137.312 138.124 1.00 53.42  ? 294 PHE   A CA  1 
ATOM   2176 C C   . PHE   A 1 268 ? 154.412 136.722 139.527 1.00 58.93  ? 294 PHE   A C   1 
ATOM   2177 O O   . PHE   A 1 268 ? 154.081 135.555 139.750 1.00 65.05  ? 294 PHE   A O   1 
ATOM   2178 C CB  . PHE   A 1 268 ? 153.329 138.428 138.051 1.00 56.12  ? 294 PHE   A CB  1 
ATOM   2179 C CG  . PHE   A 1 268 ? 153.326 139.172 136.750 1.00 56.80  ? 294 PHE   A CG  1 
ATOM   2180 C CD1 . PHE   A 1 268 ? 154.131 140.277 136.572 1.00 58.97  ? 294 PHE   A CD1 1 
ATOM   2181 C CD2 . PHE   A 1 268 ? 152.512 138.769 135.709 1.00 59.99  ? 294 PHE   A CD2 1 
ATOM   2182 C CE1 . PHE   A 1 268 ? 154.129 140.964 135.380 1.00 62.83  ? 294 PHE   A CE1 1 
ATOM   2183 C CE2 . PHE   A 1 268 ? 152.505 139.451 134.517 1.00 62.14  ? 294 PHE   A CE2 1 
ATOM   2184 C CZ  . PHE   A 1 268 ? 153.314 140.551 134.350 1.00 64.62  ? 294 PHE   A CZ  1 
ATOM   2185 N N   . SER   A 1 269 ? 154.819 137.560 140.477 1.00 55.77  ? 295 SER   A N   1 
ATOM   2186 C CA  . SER   A 1 269 ? 154.864 137.232 141.896 1.00 52.52  ? 295 SER   A CA  1 
ATOM   2187 C C   . SER   A 1 269 ? 153.900 138.117 142.675 1.00 51.82  ? 295 SER   A C   1 
ATOM   2188 O O   . SER   A 1 269 ? 154.217 138.619 143.752 1.00 50.75  ? 295 SER   A O   1 
ATOM   2189 C CB  . SER   A 1 269 ? 156.283 137.370 142.440 1.00 55.24  ? 295 SER   A CB  1 
ATOM   2190 O OG  . SER   A 1 269 ? 156.769 138.686 142.267 1.00 56.56  ? 295 SER   A OG  1 
ATOM   2191 N N   . ILE   A 1 270 ? 152.704 138.324 142.119 1.00 55.71  ? 296 ILE   A N   1 
ATOM   2192 C CA  . ILE   A 1 270 ? 151.723 139.197 142.757 1.00 54.52  ? 296 ILE   A CA  1 
ATOM   2193 C C   . ILE   A 1 270 ? 151.262 138.615 144.088 1.00 56.90  ? 296 ILE   A C   1 
ATOM   2194 O O   . ILE   A 1 270 ? 151.023 139.355 145.049 1.00 60.15  ? 296 ILE   A O   1 
ATOM   2195 C CB  . ILE   A 1 270 ? 150.540 139.466 141.803 1.00 55.56  ? 296 ILE   A CB  1 
ATOM   2196 C CG1 . ILE   A 1 270 ? 149.782 138.179 141.459 1.00 56.61  ? 296 ILE   A CG1 1 
ATOM   2197 C CG2 . ILE   A 1 270 ? 151.034 140.146 140.535 1.00 56.31  ? 296 ILE   A CG2 1 
ATOM   2198 C CD1 . ILE   A 1 270 ? 148.738 138.359 140.376 1.00 55.08  ? 296 ILE   A CD1 1 
ATOM   2199 N N   . GLY   A 1 271 ? 151.125 137.292 144.166 1.00 57.04  ? 297 GLY   A N   1 
ATOM   2200 C CA  . GLY   A 1 271 ? 150.771 136.611 145.401 1.00 56.43  ? 297 GLY   A CA  1 
ATOM   2201 C C   . GLY   A 1 271 ? 149.470 135.843 145.317 1.00 61.31  ? 297 GLY   A C   1 
ATOM   2202 O O   . GLY   A 1 271 ? 149.335 134.930 144.498 1.00 64.32  ? 297 GLY   A O   1 
ATOM   2203 N N   . MET   A 1 272 ? 148.502 136.205 146.158 1.00 60.64  ? 298 MET   A N   1 
ATOM   2204 C CA  . MET   A 1 272 ? 147.219 135.518 146.236 1.00 58.78  ? 298 MET   A CA  1 
ATOM   2205 C C   . MET   A 1 272 ? 146.144 136.175 145.378 1.00 57.70  ? 298 MET   A C   1 
ATOM   2206 O O   . MET   A 1 272 ? 144.980 135.769 145.451 1.00 61.54  ? 298 MET   A O   1 
ATOM   2207 C CB  . MET   A 1 272 ? 146.740 135.459 147.688 1.00 59.39  ? 298 MET   A CB  1 
ATOM   2208 C CG  . MET   A 1 272 ? 147.646 134.691 148.631 1.00 58.98  ? 298 MET   A CG  1 
ATOM   2209 S SD  . MET   A 1 272 ? 147.627 132.917 148.351 1.00 65.73  ? 298 MET   A SD  1 
ATOM   2210 C CE  . MET   A 1 272 ? 148.761 132.370 149.619 1.00 59.02  ? 298 MET   A CE  1 
ATOM   2211 N N   . PHE   A 1 273 ? 146.501 137.180 144.577 1.00 54.27  ? 299 PHE   A N   1 
ATOM   2212 C CA  . PHE   A 1 273 ? 145.507 137.882 143.774 1.00 55.34  ? 299 PHE   A CA  1 
ATOM   2213 C C   . PHE   A 1 273 ? 144.867 136.944 142.759 1.00 54.92  ? 299 PHE   A C   1 
ATOM   2214 O O   . PHE   A 1 273 ? 143.642 136.948 142.570 1.00 57.52  ? 299 PHE   A O   1 
ATOM   2215 C CB  . PHE   A 1 273 ? 146.176 139.073 143.078 1.00 53.75  ? 299 PHE   A CB  1 
ATOM   2216 C CG  . PHE   A 1 273 ? 145.229 140.027 142.376 1.00 52.59  ? 299 PHE   A CG  1 
ATOM   2217 C CD1 . PHE   A 1 273 ? 143.866 140.056 142.633 1.00 58.48  ? 299 PHE   A CD1 1 
ATOM   2218 C CD2 . PHE   A 1 273 ? 145.736 140.918 141.449 1.00 52.66  ? 299 PHE   A CD2 1 
ATOM   2219 C CE1 . PHE   A 1 273 ? 143.044 140.945 141.975 1.00 63.20  ? 299 PHE   A CE1 1 
ATOM   2220 C CE2 . PHE   A 1 273 ? 144.918 141.804 140.793 1.00 58.25  ? 299 PHE   A CE2 1 
ATOM   2221 C CZ  . PHE   A 1 273 ? 143.571 141.819 141.055 1.00 62.70  ? 299 PHE   A CZ  1 
ATOM   2222 N N   . SER   A 1 274 ? 145.685 136.117 142.107 1.00 49.19  ? 300 SER   A N   1 
ATOM   2223 C CA  . SER   A 1 274 ? 145.172 135.219 141.081 1.00 50.07  ? 300 SER   A CA  1 
ATOM   2224 C C   . SER   A 1 274 ? 144.174 134.228 141.662 1.00 51.96  ? 300 SER   A C   1 
ATOM   2225 O O   . SER   A 1 274 ? 143.119 133.977 141.068 1.00 53.77  ? 300 SER   A O   1 
ATOM   2226 C CB  . SER   A 1 274 ? 146.331 134.483 140.413 1.00 52.57  ? 300 SER   A CB  1 
ATOM   2227 O OG  . SER   A 1 274 ? 145.853 133.527 139.484 1.00 57.87  ? 300 SER   A OG  1 
ATOM   2228 N N   . TYR   A 1 275 ? 144.479 133.670 142.831 1.00 52.09  ? 301 TYR   A N   1 
ATOM   2229 C CA  . TYR   A 1 275 ? 143.580 132.693 143.434 1.00 52.03  ? 301 TYR   A CA  1 
ATOM   2230 C C   . TYR   A 1 275 ? 142.284 133.347 143.895 1.00 51.55  ? 301 TYR   A C   1 
ATOM   2231 O O   . TYR   A 1 275 ? 141.209 132.747 143.786 1.00 55.61  ? 301 TYR   A O   1 
ATOM   2232 C CB  . TYR   A 1 275 ? 144.278 131.986 144.595 1.00 53.99  ? 301 TYR   A CB  1 
ATOM   2233 C CG  . TYR   A 1 275 ? 145.591 131.345 144.210 1.00 56.14  ? 301 TYR   A CG  1 
ATOM   2234 C CD1 . TYR   A 1 275 ? 145.626 130.227 143.398 1.00 57.27  ? 301 TYR   A CD1 1 
ATOM   2235 C CD2 . TYR   A 1 275 ? 146.793 131.863 144.658 1.00 57.28  ? 301 TYR   A CD2 1 
ATOM   2236 C CE1 . TYR   A 1 275 ? 146.818 129.643 143.044 1.00 58.32  ? 301 TYR   A CE1 1 
ATOM   2237 C CE2 . TYR   A 1 275 ? 147.990 131.285 144.309 1.00 57.82  ? 301 TYR   A CE2 1 
ATOM   2238 C CZ  . TYR   A 1 275 ? 147.996 130.176 143.500 1.00 58.60  ? 301 TYR   A CZ  1 
ATOM   2239 O OH  . TYR   A 1 275 ? 149.190 129.594 143.148 1.00 60.35  ? 301 TYR   A OH  1 
ATOM   2240 N N   . VAL   A 1 276 ? 142.361 134.574 144.411 1.00 49.23  ? 302 VAL   A N   1 
ATOM   2241 C CA  . VAL   A 1 276 ? 141.149 135.279 144.820 1.00 49.58  ? 302 VAL   A CA  1 
ATOM   2242 C C   . VAL   A 1 276 ? 140.253 135.543 143.616 1.00 53.41  ? 302 VAL   A C   1 
ATOM   2243 O O   . VAL   A 1 276 ? 139.033 135.340 143.678 1.00 56.13  ? 302 VAL   A O   1 
ATOM   2244 C CB  . VAL   A 1 276 ? 141.509 136.581 145.562 1.00 53.76  ? 302 VAL   A CB  1 
ATOM   2245 C CG1 . VAL   A 1 276 ? 140.281 137.456 145.749 1.00 53.82  ? 302 VAL   A CG1 1 
ATOM   2246 C CG2 . VAL   A 1 276 ? 142.123 136.263 146.913 1.00 53.57  ? 302 VAL   A CG2 1 
ATOM   2247 N N   . MET   A 1 277 ? 140.833 136.000 142.504 1.00 50.08  ? 303 MET   A N   1 
ATOM   2248 C CA  . MET   A 1 277 ? 140.017 136.233 141.316 1.00 49.25  ? 303 MET   A CA  1 
ATOM   2249 C C   . MET   A 1 277 ? 139.449 134.926 140.768 1.00 49.35  ? 303 MET   A C   1 
ATOM   2250 O O   . MET   A 1 277 ? 138.310 134.892 140.283 1.00 52.18  ? 303 MET   A O   1 
ATOM   2251 C CB  . MET   A 1 277 ? 140.828 136.965 140.248 1.00 51.96  ? 303 MET   A CB  1 
ATOM   2252 C CG  . MET   A 1 277 ? 141.312 138.356 140.658 1.00 54.73  ? 303 MET   A CG  1 
ATOM   2253 S SD  . MET   A 1 277 ? 140.010 139.531 141.084 1.00 70.68  ? 303 MET   A SD  1 
ATOM   2254 C CE  . MET   A 1 277 ? 139.273 139.865 139.492 1.00 58.44  ? 303 MET   A CE  1 
ATOM   2255 N N   . LEU   A 1 278 ? 140.222 133.838 140.836 1.00 47.84  ? 304 LEU   A N   1 
ATOM   2256 C CA  . LEU   A 1 278 ? 139.696 132.539 140.427 1.00 46.96  ? 304 LEU   A CA  1 
ATOM   2257 C C   . LEU   A 1 278 ? 138.510 132.127 141.289 1.00 45.62  ? 304 LEU   A C   1 
ATOM   2258 O O   . LEU   A 1 278 ? 137.519 131.596 140.780 1.00 47.18  ? 304 LEU   A O   1 
ATOM   2259 C CB  . LEU   A 1 278 ? 140.791 131.476 140.505 1.00 48.53  ? 304 LEU   A CB  1 
ATOM   2260 C CG  . LEU   A 1 278 ? 141.832 131.406 139.390 1.00 46.46  ? 304 LEU   A CG  1 
ATOM   2261 C CD1 . LEU   A 1 278 ? 142.905 130.403 139.760 1.00 48.61  ? 304 LEU   A CD1 1 
ATOM   2262 C CD2 . LEU   A 1 278 ? 141.195 131.030 138.069 1.00 48.21  ? 304 LEU   A CD2 1 
ATOM   2263 N N   . ALA   A 1 279 ? 138.601 132.350 142.599 1.00 44.03  ? 305 ALA   A N   1 
ATOM   2264 C CA  . ALA   A 1 279 ? 137.491 132.021 143.487 1.00 44.35  ? 305 ALA   A CA  1 
ATOM   2265 C C   . ALA   A 1 279 ? 136.281 132.902 143.209 1.00 46.23  ? 305 ALA   A C   1 
ATOM   2266 O O   . ALA   A 1 279 ? 135.137 132.474 143.395 1.00 45.71  ? 305 ALA   A O   1 
ATOM   2267 C CB  . ALA   A 1 279 ? 137.930 132.160 144.943 1.00 48.81  ? 305 ALA   A CB  1 
ATOM   2268 N N   . SER   A 1 280 ? 136.512 134.151 142.799 1.00 48.22  ? 306 SER   A N   1 
ATOM   2269 C CA  . SER   A 1 280 ? 135.402 135.044 142.485 1.00 46.02  ? 306 SER   A CA  1 
ATOM   2270 C C   . SER   A 1 280 ? 134.755 134.727 141.142 1.00 45.17  ? 306 SER   A C   1 
ATOM   2271 O O   . SER   A 1 280 ? 133.597 135.102 140.929 1.00 49.24  ? 306 SER   A O   1 
ATOM   2272 C CB  . SER   A 1 280 ? 135.875 136.496 142.487 1.00 45.64  ? 306 SER   A CB  1 
ATOM   2273 O OG  . SER   A 1 280 ? 136.580 136.800 141.299 1.00 47.29  ? 306 SER   A OG  1 
ATOM   2274 N N   . SER   A 1 281 ? 135.479 134.077 140.230 1.00 44.57  ? 307 SER   A N   1 
ATOM   2275 C CA  . SER   A 1 281 ? 134.914 133.776 138.913 1.00 44.68  ? 307 SER   A CA  1 
ATOM   2276 C C   . SER   A 1 281 ? 133.634 132.949 138.976 1.00 43.87  ? 307 SER   A C   1 
ATOM   2277 O O   . SER   A 1 281 ? 132.677 133.286 138.258 1.00 45.17  ? 307 SER   A O   1 
ATOM   2278 C CB  . SER   A 1 281 ? 135.974 133.092 138.044 1.00 48.61  ? 307 SER   A CB  1 
ATOM   2279 O OG  . SER   A 1 281 ? 136.798 134.051 137.407 1.00 52.95  ? 307 SER   A OG  1 
ATOM   2280 N N   . PRO   A 1 282 ? 133.533 131.881 139.779 1.00 42.66  ? 308 PRO   A N   1 
ATOM   2281 C CA  . PRO   A 1 282 ? 132.254 131.156 139.882 1.00 40.32  ? 308 PRO   A CA  1 
ATOM   2282 C C   . PRO   A 1 282 ? 131.095 131.989 140.404 1.00 43.69  ? 308 PRO   A C   1 
ATOM   2283 O O   . PRO   A 1 282 ? 129.942 131.574 140.235 1.00 47.46  ? 308 PRO   A O   1 
ATOM   2284 C CB  . PRO   A 1 282 ? 132.574 130.018 140.853 1.00 38.95  ? 308 PRO   A CB  1 
ATOM   2285 C CG  . PRO   A 1 282 ? 134.006 129.778 140.693 1.00 44.71  ? 308 PRO   A CG  1 
ATOM   2286 C CD  . PRO   A 1 282 ? 134.640 131.092 140.346 1.00 46.90  ? 308 PRO   A CD  1 
ATOM   2287 N N   . LEU   A 1 283 ? 131.357 133.135 141.033 1.00 43.23  ? 309 LEU   A N   1 
ATOM   2288 C CA  . LEU   A 1 283 ? 130.296 133.897 141.681 1.00 39.61  ? 309 LEU   A CA  1 
ATOM   2289 C C   . LEU   A 1 283 ? 129.273 134.416 140.678 1.00 42.06  ? 309 LEU   A C   1 
ATOM   2290 O O   . LEU   A 1 283 ? 128.110 134.629 141.037 1.00 42.40  ? 309 LEU   A O   1 
ATOM   2291 C CB  . LEU   A 1 283 ? 130.920 135.049 142.469 1.00 39.03  ? 309 LEU   A CB  1 
ATOM   2292 C CG  . LEU   A 1 283 ? 130.132 135.693 143.608 1.00 43.89  ? 309 LEU   A CG  1 
ATOM   2293 C CD1 . LEU   A 1 283 ? 129.771 134.686 144.685 1.00 47.03  ? 309 LEU   A CD1 1 
ATOM   2294 C CD2 . LEU   A 1 283 ? 130.935 136.820 144.211 1.00 43.52  ? 309 LEU   A CD2 1 
ATOM   2295 N N   . PHE   A 1 284 ? 129.677 134.622 139.423 1.00 44.75  ? 310 PHE   A N   1 
ATOM   2296 C CA  . PHE   A 1 284 ? 128.736 135.010 138.378 1.00 43.60  ? 310 PHE   A CA  1 
ATOM   2297 C C   . PHE   A 1 284 ? 127.821 133.871 137.948 1.00 44.70  ? 310 PHE   A C   1 
ATOM   2298 O O   . PHE   A 1 284 ? 126.837 134.126 137.249 1.00 44.83  ? 310 PHE   A O   1 
ATOM   2299 C CB  . PHE   A 1 284 ? 129.489 135.529 137.155 1.00 42.39  ? 310 PHE   A CB  1 
ATOM   2300 C CG  . PHE   A 1 284 ? 130.164 136.844 137.373 1.00 44.66  ? 310 PHE   A CG  1 
ATOM   2301 C CD1 . PHE   A 1 284 ? 131.430 136.905 137.918 1.00 44.58  ? 310 PHE   A CD1 1 
ATOM   2302 C CD2 . PHE   A 1 284 ? 129.536 138.022 137.028 1.00 44.41  ? 310 PHE   A CD2 1 
ATOM   2303 C CE1 . PHE   A 1 284 ? 132.052 138.115 138.116 1.00 42.03  ? 310 PHE   A CE1 1 
ATOM   2304 C CE2 . PHE   A 1 284 ? 130.154 139.231 137.224 1.00 40.82  ? 310 PHE   A CE2 1 
ATOM   2305 C CZ  . PHE   A 1 284 ? 131.412 139.278 137.768 1.00 38.69  ? 310 PHE   A CZ  1 
ATOM   2306 N N   . CYS   A 1 285 ? 128.116 132.634 138.341 1.00 44.67  ? 311 CYS   A N   1 
ATOM   2307 C CA  . CYS   A 1 285 ? 127.283 131.501 137.976 1.00 44.55  ? 311 CYS   A CA  1 
ATOM   2308 C C   . CYS   A 1 285 ? 125.983 131.538 138.776 1.00 47.11  ? 311 CYS   A C   1 
ATOM   2309 O O   . CYS   A 1 285 ? 125.694 132.494 139.501 1.00 50.03  ? 311 CYS   A O   1 
ATOM   2310 C CB  . CYS   A 1 285 ? 128.037 130.195 138.209 1.00 45.03  ? 311 CYS   A CB  1 
ATOM   2311 S SG  . CYS   A 1 285 ? 129.652 130.121 137.415 1.00 62.54  ? 311 CYS   A SG  1 
ATOM   2312 N N   . SER   A 1 286 ? 125.178 130.493 138.621 1.00 44.94  ? 312 SER   A N   1 
ATOM   2313 C CA  . SER   A 1 286 ? 123.889 130.454 139.291 1.00 42.57  ? 312 SER   A CA  1 
ATOM   2314 C C   . SER   A 1 286 ? 124.098 130.461 140.806 1.00 45.37  ? 312 SER   A C   1 
ATOM   2315 O O   . SER   A 1 286 ? 125.078 129.886 141.293 1.00 47.53  ? 312 SER   A O   1 
ATOM   2316 C CB  . SER   A 1 286 ? 123.104 129.212 138.872 1.00 46.94  ? 312 SER   A CB  1 
ATOM   2317 O OG  . SER   A 1 286 ? 123.818 128.029 139.183 1.00 53.45  ? 312 SER   A OG  1 
ATOM   2318 N N   . PRO   A 1 287 ? 123.211 131.090 141.589 1.00 42.50  ? 313 PRO   A N   1 
ATOM   2319 C CA  . PRO   A 1 287 ? 123.453 131.164 143.038 1.00 37.73  ? 313 PRO   A CA  1 
ATOM   2320 C C   . PRO   A 1 287 ? 123.397 129.835 143.774 1.00 41.84  ? 313 PRO   A C   1 
ATOM   2321 O O   . PRO   A 1 287 ? 123.634 129.830 144.987 1.00 48.65  ? 313 PRO   A O   1 
ATOM   2322 C CB  . PRO   A 1 287 ? 122.332 132.088 143.535 1.00 38.45  ? 313 PRO   A CB  1 
ATOM   2323 C CG  . PRO   A 1 287 ? 121.904 132.843 142.369 1.00 40.07  ? 313 PRO   A CG  1 
ATOM   2324 C CD  . PRO   A 1 287 ? 122.055 131.926 141.210 1.00 46.15  ? 313 PRO   A CD  1 
ATOM   2325 N N   . GLU   A 1 288 ? 123.101 128.713 143.105 1.00 41.92  ? 314 GLU   A N   1 
ATOM   2326 C CA  . GLU   A 1 288 ? 122.910 127.427 143.767 1.00 41.79  ? 314 GLU   A CA  1 
ATOM   2327 C C   . GLU   A 1 288 ? 123.742 126.312 143.141 1.00 43.91  ? 314 GLU   A C   1 
ATOM   2328 O O   . GLU   A 1 288 ? 123.385 125.139 143.277 1.00 49.65  ? 314 GLU   A O   1 
ATOM   2329 C CB  . GLU   A 1 288 ? 121.427 127.051 143.754 1.00 43.50  ? 314 GLU   A CB  1 
ATOM   2330 C CG  . GLU   A 1 288 ? 120.804 126.996 142.369 1.00 47.28  ? 314 GLU   A CG  1 
ATOM   2331 C CD  . GLU   A 1 288 ? 119.331 126.652 142.410 1.00 56.48  ? 314 GLU   A CD  1 
ATOM   2332 O OE1 . GLU   A 1 288 ? 118.796 126.453 143.521 1.00 55.02  ? 314 GLU   A OE1 1 
ATOM   2333 O OE2 . GLU   A 1 288 ? 118.706 126.581 141.332 1.00 65.03  ? 314 GLU   A OE2 1 
ATOM   2334 N N   . TRP   A 1 289 ? 124.837 126.639 142.455 1.00 42.38  ? 315 TRP   A N   1 
ATOM   2335 C CA  . TRP   A 1 289 ? 125.654 125.590 141.850 1.00 43.02  ? 315 TRP   A CA  1 
ATOM   2336 C C   . TRP   A 1 289 ? 126.249 124.599 142.852 1.00 46.55  ? 315 TRP   A C   1 
ATOM   2337 O O   . TRP   A 1 289 ? 126.270 123.395 142.532 1.00 54.99  ? 315 TRP   A O   1 
ATOM   2338 C CB  . TRP   A 1 289 ? 126.748 126.204 140.961 1.00 45.60  ? 315 TRP   A CB  1 
ATOM   2339 C CG  . TRP   A 1 289 ? 127.814 126.992 141.646 1.00 44.10  ? 315 TRP   A CG  1 
ATOM   2340 C CD1 . TRP   A 1 289 ? 127.853 128.342 141.808 1.00 45.81  ? 315 TRP   A CD1 1 
ATOM   2341 C CD2 . TRP   A 1 289 ? 129.006 126.482 142.254 1.00 40.69  ? 315 TRP   A CD2 1 
ATOM   2342 N NE1 . TRP   A 1 289 ? 128.989 128.707 142.480 1.00 46.18  ? 315 TRP   A NE1 1 
ATOM   2343 C CE2 . TRP   A 1 289 ? 129.716 127.582 142.764 1.00 39.95  ? 315 TRP   A CE2 1 
ATOM   2344 C CE3 . TRP   A 1 289 ? 129.542 125.204 142.416 1.00 45.61  ? 315 TRP   A CE3 1 
ATOM   2345 C CZ2 . TRP   A 1 289 ? 130.930 127.445 143.425 1.00 39.03  ? 315 TRP   A CZ2 1 
ATOM   2346 C CZ3 . TRP   A 1 289 ? 130.747 125.069 143.074 1.00 46.86  ? 315 TRP   A CZ3 1 
ATOM   2347 C CH2 . TRP   A 1 289 ? 131.427 126.184 143.570 1.00 41.05  ? 315 TRP   A CH2 1 
ATOM   2348 N N   . PRO   A 1 290 ? 126.758 124.994 144.032 1.00 42.10  ? 316 PRO   A N   1 
ATOM   2349 C CA  . PRO   A 1 290 ? 127.299 123.968 144.936 1.00 42.24  ? 316 PRO   A CA  1 
ATOM   2350 C C   . PRO   A 1 290 ? 126.259 122.963 145.381 1.00 45.62  ? 316 PRO   A C   1 
ATOM   2351 O O   . PRO   A 1 290 ? 126.599 121.804 145.633 1.00 52.69  ? 316 PRO   A O   1 
ATOM   2352 C CB  . PRO   A 1 290 ? 127.835 124.783 146.124 1.00 44.41  ? 316 PRO   A CB  1 
ATOM   2353 C CG  . PRO   A 1 290 ? 127.853 126.186 145.670 1.00 47.74  ? 316 PRO   A CG  1 
ATOM   2354 C CD  . PRO   A 1 290 ? 126.703 126.283 144.743 1.00 47.45  ? 316 PRO   A CD  1 
ATOM   2355 N N   . ARG   A 1 291 ? 124.995 123.371 145.480 1.00 44.51  ? 317 ARG   A N   1 
ATOM   2356 C CA  . ARG   A 1 291 ? 123.951 122.445 145.898 1.00 45.63  ? 317 ARG   A CA  1 
ATOM   2357 C C   . ARG   A 1 291 ? 123.763 121.329 144.878 1.00 47.42  ? 317 ARG   A C   1 
ATOM   2358 O O   . ARG   A 1 291 ? 123.684 120.148 145.244 1.00 55.49  ? 317 ARG   A O   1 
ATOM   2359 C CB  . ARG   A 1 291 ? 122.649 123.213 146.120 1.00 45.40  ? 317 ARG   A CB  1 
ATOM   2360 C CG  . ARG   A 1 291 ? 121.549 122.401 146.759 1.00 50.78  ? 317 ARG   A CG  1 
ATOM   2361 C CD  . ARG   A 1 291 ? 120.367 123.262 147.170 1.00 50.42  ? 317 ARG   A CD  1 
ATOM   2362 N NE  . ARG   A 1 291 ? 120.601 123.962 148.430 1.00 48.44  ? 317 ARG   A NE  1 
ATOM   2363 C CZ  . ARG   A 1 291 ? 121.022 125.215 148.563 1.00 47.95  ? 317 ARG   A CZ  1 
ATOM   2364 N NH1 . ARG   A 1 291 ? 121.290 125.982 147.518 1.00 46.11  ? 317 ARG   A NH1 1 
ATOM   2365 N NH2 . ARG   A 1 291 ? 121.177 125.716 149.785 1.00 49.10  ? 317 ARG   A NH2 1 
ATOM   2366 N N   . LYS   A 1 292 ? 123.714 121.674 143.592 1.00 45.36  ? 318 LYS   A N   1 
ATOM   2367 C CA  . LYS   A 1 292 ? 123.536 120.646 142.575 1.00 53.07  ? 318 LYS   A CA  1 
ATOM   2368 C C   . LYS   A 1 292 ? 124.809 119.830 142.388 1.00 55.71  ? 318 LYS   A C   1 
ATOM   2369 O O   . LYS   A 1 292 ? 124.744 118.653 142.015 1.00 61.81  ? 318 LYS   A O   1 
ATOM   2370 C CB  . LYS   A 1 292 ? 123.080 121.269 141.253 1.00 58.42  ? 318 LYS   A CB  1 
ATOM   2371 C CG  . LYS   A 1 292 ? 124.047 122.241 140.608 1.00 57.83  ? 318 LYS   A CG  1 
ATOM   2372 C CD  . LYS   A 1 292 ? 123.464 122.806 139.319 1.00 60.34  ? 318 LYS   A CD  1 
ATOM   2373 C CE  . LYS   A 1 292 ? 124.484 123.626 138.544 1.00 62.49  ? 318 LYS   A CE  1 
ATOM   2374 N NZ  . LYS   A 1 292 ? 123.931 124.132 137.256 1.00 65.26  ? 318 LYS   A NZ  1 
ATOM   2375 N N   . LEU   A 1 293 ? 125.977 120.428 142.632 1.00 52.08  ? 319 LEU   A N   1 
ATOM   2376 C CA  . LEU   A 1 293 ? 127.199 119.625 142.662 1.00 52.45  ? 319 LEU   A CA  1 
ATOM   2377 C C   . LEU   A 1 293 ? 127.166 118.612 143.803 1.00 57.50  ? 319 LEU   A C   1 
ATOM   2378 O O   . LEU   A 1 293 ? 127.599 117.467 143.638 1.00 61.56  ? 319 LEU   A O   1 
ATOM   2379 C CB  . LEU   A 1 293 ? 128.431 120.522 142.782 1.00 51.68  ? 319 LEU   A CB  1 
ATOM   2380 C CG  . LEU   A 1 293 ? 129.140 120.833 141.463 1.00 52.87  ? 319 LEU   A CG  1 
ATOM   2381 C CD1 . LEU   A 1 293 ? 128.266 121.677 140.554 1.00 53.12  ? 319 LEU   A CD1 1 
ATOM   2382 C CD2 . LEU   A 1 293 ? 130.464 121.525 141.722 1.00 50.28  ? 319 LEU   A CD2 1 
ATOM   2383 N N   . VAL   A 1 294 ? 126.669 119.021 144.973 1.00 61.64  ? 320 VAL   A N   1 
ATOM   2384 C CA  . VAL   A 1 294 ? 126.579 118.115 146.116 1.00 61.28  ? 320 VAL   A CA  1 
ATOM   2385 C C   . VAL   A 1 294 ? 125.597 116.989 145.827 1.00 62.58  ? 320 VAL   A C   1 
ATOM   2386 O O   . VAL   A 1 294 ? 125.838 115.830 146.188 1.00 67.07  ? 320 VAL   A O   1 
ATOM   2387 C CB  . VAL   A 1 294 ? 126.186 118.897 147.385 1.00 58.80  ? 320 VAL   A CB  1 
ATOM   2388 C CG1 . VAL   A 1 294 ? 125.733 117.959 148.497 1.00 59.23  ? 320 VAL   A CG1 1 
ATOM   2389 C CG2 . VAL   A 1 294 ? 127.351 119.743 147.866 1.00 58.70  ? 320 VAL   A CG2 1 
ATOM   2390 N N   . SER   A 1 295 ? 124.470 117.310 145.188 1.00 64.03  ? 321 SER   A N   1 
ATOM   2391 C CA  . SER   A 1 295 ? 123.440 116.301 144.953 1.00 67.49  ? 321 SER   A CA  1 
ATOM   2392 C C   . SER   A 1 295 ? 123.953 115.175 144.064 1.00 69.53  ? 321 SER   A C   1 
ATOM   2393 O O   . SER   A 1 295 ? 123.602 114.007 144.267 1.00 73.10  ? 321 SER   A O   1 
ATOM   2394 C CB  . SER   A 1 295 ? 122.206 116.951 144.329 1.00 66.83  ? 321 SER   A CB  1 
ATOM   2395 O OG  . SER   A 1 295 ? 121.636 117.906 145.206 1.00 64.86  ? 321 SER   A OG  1 
ATOM   2396 N N   . TYR   A 1 296 ? 124.788 115.502 143.078 1.00 67.74  ? 322 TYR   A N   1 
ATOM   2397 C CA  . TYR   A 1 296 ? 125.297 114.519 142.122 1.00 67.76  ? 322 TYR   A CA  1 
ATOM   2398 C C   . TYR   A 1 296 ? 126.513 113.779 142.686 1.00 74.98  ? 322 TYR   A C   1 
ATOM   2399 O O   . TYR   A 1 296 ? 127.611 113.808 142.131 1.00 79.22  ? 322 TYR   A O   1 
ATOM   2400 C CB  . TYR   A 1 296 ? 125.645 115.206 140.807 1.00 67.90  ? 322 TYR   A CB  1 
ATOM   2401 C CG  . TYR   A 1 296 ? 124.515 115.979 140.153 1.00 72.88  ? 322 TYR   A CG  1 
ATOM   2402 C CD1 . TYR   A 1 296 ? 123.182 115.645 140.374 1.00 73.72  ? 322 TYR   A CD1 1 
ATOM   2403 C CD2 . TYR   A 1 296 ? 124.787 117.039 139.301 1.00 74.71  ? 322 TYR   A CD2 1 
ATOM   2404 C CE1 . TYR   A 1 296 ? 122.159 116.351 139.772 1.00 78.63  ? 322 TYR   A CE1 1 
ATOM   2405 C CE2 . TYR   A 1 296 ? 123.770 117.750 138.694 1.00 76.19  ? 322 TYR   A CE2 1 
ATOM   2406 C CZ  . TYR   A 1 296 ? 122.457 117.402 138.933 1.00 81.68  ? 322 TYR   A CZ  1 
ATOM   2407 O OH  . TYR   A 1 296 ? 121.439 118.106 138.332 1.00 79.45  ? 322 TYR   A OH  1 
ATOM   2408 N N   . CYS   A 1 297 ? 126.299 113.104 143.811 1.00 79.34  ? 323 CYS   A N   1 
ATOM   2409 C CA  . CYS   A 1 297 ? 127.351 112.361 144.489 1.00 81.53  ? 323 CYS   A CA  1 
ATOM   2410 C C   . CYS   A 1 297 ? 126.724 111.171 145.199 1.00 79.51  ? 323 CYS   A C   1 
ATOM   2411 O O   . CYS   A 1 297 ? 125.498 111.111 145.348 1.00 81.48  ? 323 CYS   A O   1 
ATOM   2412 C CB  . CYS   A 1 297 ? 128.106 113.242 145.494 1.00 82.85  ? 323 CYS   A CB  1 
ATOM   2413 S SG  . CYS   A 1 297 ? 129.232 114.438 144.742 1.00 88.55  ? 323 CYS   A SG  1 
ATOM   2414 N N   . PRO   A 1 298 ? 127.530 110.205 145.640 1.00 79.40  ? 324 PRO   A N   1 
ATOM   2415 C CA  . PRO   A 1 298 ? 126.978 109.090 146.418 1.00 82.54  ? 324 PRO   A CA  1 
ATOM   2416 C C   . PRO   A 1 298 ? 126.399 109.557 147.743 1.00 83.30  ? 324 PRO   A C   1 
ATOM   2417 O O   . PRO   A 1 298 ? 126.807 110.569 148.315 1.00 86.97  ? 324 PRO   A O   1 
ATOM   2418 C CB  . PRO   A 1 298 ? 128.184 108.172 146.641 1.00 86.43  ? 324 PRO   A CB  1 
ATOM   2419 C CG  . PRO   A 1 298 ? 129.131 108.515 145.567 1.00 88.14  ? 324 PRO   A CG  1 
ATOM   2420 C CD  . PRO   A 1 298 ? 128.943 109.972 145.294 1.00 84.70  ? 324 PRO   A CD  1 
ATOM   2421 N N   . ARG   A 1 299 ? 125.426 108.784 148.230 1.00 82.07  ? 325 ARG   A N   1 
ATOM   2422 C CA  . ARG   A 1 299 ? 124.715 109.153 149.450 1.00 86.51  ? 325 ARG   A CA  1 
ATOM   2423 C C   . ARG   A 1 299 ? 125.654 109.191 150.651 1.00 90.48  ? 325 ARG   A C   1 
ATOM   2424 O O   . ARG   A 1 299 ? 125.521 110.057 151.527 1.00 91.83  ? 325 ARG   A O   1 
ATOM   2425 C CB  . ARG   A 1 299 ? 123.571 108.169 149.695 1.00 88.76  ? 325 ARG   A CB  1 
ATOM   2426 C CG  . ARG   A 1 299 ? 122.559 108.612 150.743 1.00 95.37  ? 325 ARG   A CG  1 
ATOM   2427 C CD  . ARG   A 1 299 ? 121.644 109.706 150.216 1.00 96.92  ? 325 ARG   A CD  1 
ATOM   2428 N NE  . ARG   A 1 299 ? 120.607 110.060 151.178 1.00 100.88 ? 325 ARG   A NE  1 
ATOM   2429 C CZ  . ARG   A 1 299 ? 119.620 110.917 150.950 1.00 98.06  ? 325 ARG   A CZ  1 
ATOM   2430 N NH1 . ARG   A 1 299 ? 119.490 111.538 149.786 1.00 96.03  ? 325 ARG   A NH1 1 
ATOM   2431 N NH2 . ARG   A 1 299 ? 118.736 111.158 151.914 1.00 95.45  ? 325 ARG   A NH2 1 
ATOM   2432 N N   . ARG   A 1 300 ? 126.600 108.250 150.717 1.00 89.99  ? 326 ARG   A N   1 
ATOM   2433 C CA  . ARG   A 1 300 ? 127.521 108.204 151.848 1.00 91.62  ? 326 ARG   A CA  1 
ATOM   2434 C C   . ARG   A 1 300 ? 128.337 109.486 151.943 1.00 90.60  ? 326 ARG   A C   1 
ATOM   2435 O O   . ARG   A 1 300 ? 128.527 110.031 153.036 1.00 88.27  ? 326 ARG   A O   1 
ATOM   2436 C CB  . ARG   A 1 300 ? 128.445 106.992 151.722 1.00 96.57  ? 326 ARG   A CB  1 
ATOM   2437 C CG  . ARG   A 1 300 ? 127.724 105.651 151.673 1.00 101.00 ? 326 ARG   A CG  1 
ATOM   2438 C CD  . ARG   A 1 300 ? 128.703 104.503 151.480 1.00 105.52 ? 326 ARG   A CD  1 
ATOM   2439 N NE  . ARG   A 1 300 ? 128.024 103.224 151.304 1.00 110.28 ? 326 ARG   A NE  1 
ATOM   2440 C CZ  . ARG   A 1 300 ? 128.633 102.062 151.101 1.00 112.16 ? 326 ARG   A CZ  1 
ATOM   2441 N NH1 . ARG   A 1 300 ? 129.954 101.968 151.040 1.00 109.82 ? 326 ARG   A NH1 1 
ATOM   2442 N NH2 . ARG   A 1 300 ? 127.899 100.962 150.955 1.00 111.59 ? 326 ARG   A NH2 1 
ATOM   2443 N N   . LEU   A 1 301 ? 128.830 109.984 150.806 1.00 89.80  ? 327 LEU   A N   1 
ATOM   2444 C CA  . LEU   A 1 301 ? 129.494 111.281 150.806 1.00 88.12  ? 327 LEU   A CA  1 
ATOM   2445 C C   . LEU   A 1 301 ? 128.525 112.390 151.195 1.00 87.04  ? 327 LEU   A C   1 
ATOM   2446 O O   . LEU   A 1 301 ? 128.893 113.318 151.924 1.00 85.15  ? 327 LEU   A O   1 
ATOM   2447 C CB  . LEU   A 1 301 ? 130.108 111.561 149.433 1.00 85.64  ? 327 LEU   A CB  1 
ATOM   2448 C CG  . LEU   A 1 301 ? 131.242 110.644 148.962 1.00 87.72  ? 327 LEU   A CG  1 
ATOM   2449 C CD1 . LEU   A 1 301 ? 131.713 111.044 147.568 1.00 87.87  ? 327 LEU   A CD1 1 
ATOM   2450 C CD2 . LEU   A 1 301 ? 132.416 110.654 149.935 1.00 86.57  ? 327 LEU   A CD2 1 
ATOM   2451 N N   . GLN   A 1 302 ? 127.276 112.307 150.727 1.00 88.98  ? 328 GLN   A N   1 
ATOM   2452 C CA  . GLN   A 1 302 ? 126.285 113.322 151.071 1.00 84.99  ? 328 GLN   A CA  1 
ATOM   2453 C C   . GLN   A 1 302 ? 125.999 113.364 152.564 1.00 84.81  ? 328 GLN   A C   1 
ATOM   2454 O O   . GLN   A 1 302 ? 125.505 114.384 153.057 1.00 84.84  ? 328 GLN   A O   1 
ATOM   2455 C CB  . GLN   A 1 302 ? 124.984 113.082 150.305 1.00 83.20  ? 328 GLN   A CB  1 
ATOM   2456 C CG  . GLN   A 1 302 ? 125.072 113.395 148.825 1.00 81.09  ? 328 GLN   A CG  1 
ATOM   2457 C CD  . GLN   A 1 302 ? 123.768 113.149 148.099 1.00 81.53  ? 328 GLN   A CD  1 
ATOM   2458 O OE1 . GLN   A 1 302 ? 122.761 112.795 148.711 1.00 83.75  ? 328 GLN   A OE1 1 
ATOM   2459 N NE2 . GLN   A 1 302 ? 123.778 113.335 146.786 1.00 80.47  ? 328 GLN   A NE2 1 
ATOM   2460 N N   . GLN   A 1 303 ? 126.294 112.289 153.297 1.00 87.32  ? 329 GLN   A N   1 
ATOM   2461 C CA  . GLN   A 1 303 ? 126.147 112.330 154.749 1.00 92.65  ? 329 GLN   A CA  1 
ATOM   2462 C C   . GLN   A 1 303 ? 127.132 113.280 155.427 1.00 86.65  ? 329 GLN   A C   1 
ATOM   2463 O O   . GLN   A 1 303 ? 126.939 113.590 156.607 1.00 77.93  ? 329 GLN   A O   1 
ATOM   2464 C CB  . GLN   A 1 303 ? 126.316 110.929 155.340 1.00 94.15  ? 329 GLN   A CB  1 
ATOM   2465 C CG  . GLN   A 1 303 ? 125.227 109.947 154.943 1.00 95.66  ? 329 GLN   A CG  1 
ATOM   2466 C CD  . GLN   A 1 303 ? 125.477 108.554 155.486 1.00 100.26 ? 329 GLN   A CD  1 
ATOM   2467 O OE1 . GLN   A 1 303 ? 126.380 108.344 156.295 1.00 100.43 ? 329 GLN   A OE1 1 
ATOM   2468 N NE2 . GLN   A 1 303 ? 124.677 107.593 155.040 1.00 98.03  ? 329 GLN   A NE2 1 
ATOM   2469 N N   . LEU   A 1 304 ? 128.168 113.747 154.723 1.00 86.76  ? 330 LEU   A N   1 
ATOM   2470 C CA  . LEU   A 1 304 ? 129.155 114.669 155.276 1.00 89.75  ? 330 LEU   A CA  1 
ATOM   2471 C C   . LEU   A 1 304 ? 129.082 116.071 154.691 1.00 85.03  ? 330 LEU   A C   1 
ATOM   2472 O O   . LEU   A 1 304 ? 129.384 117.035 155.397 1.00 80.37  ? 330 LEU   A O   1 
ATOM   2473 C CB  . LEU   A 1 304 ? 130.573 114.125 155.050 1.00 90.82  ? 330 LEU   A CB  1 
ATOM   2474 C CG  . LEU   A 1 304 ? 130.878 112.729 155.599 1.00 92.97  ? 330 LEU   A CG  1 
ATOM   2475 C CD1 . LEU   A 1 304 ? 132.286 112.311 155.206 1.00 91.61  ? 330 LEU   A CD1 1 
ATOM   2476 C CD2 . LEU   A 1 304 ? 130.706 112.680 157.110 1.00 91.46  ? 330 LEU   A CD2 1 
ATOM   2477 N N   . LEU   A 1 305 ? 128.694 116.210 153.430 1.00 76.98  ? 331 LEU   A N   1 
ATOM   2478 C CA  . LEU   A 1 305 ? 128.599 117.509 152.785 1.00 68.02  ? 331 LEU   A CA  1 
ATOM   2479 C C   . LEU   A 1 305 ? 127.355 118.244 153.276 1.00 65.60  ? 331 LEU   A C   1 
ATOM   2480 O O   . LEU   A 1 305 ? 126.465 117.642 153.879 1.00 64.25  ? 331 LEU   A O   1 
ATOM   2481 C CB  . LEU   A 1 305 ? 128.590 117.321 151.270 1.00 72.38  ? 331 LEU   A CB  1 
ATOM   2482 C CG  . LEU   A 1 305 ? 129.816 116.622 150.675 1.00 73.66  ? 331 LEU   A CG  1 
ATOM   2483 C CD1 . LEU   A 1 305 ? 129.643 116.441 149.175 1.00 75.31  ? 331 LEU   A CD1 1 
ATOM   2484 C CD2 . LEU   A 1 305 ? 131.098 117.387 150.972 1.00 70.57  ? 331 LEU   A CD2 1 
ATOM   2485 N N   . PRO   A 1 306 ? 127.259 119.573 153.035 1.00 61.60  ? 332 PRO   A N   1 
ATOM   2486 C CA  . PRO   A 1 306 ? 126.153 120.346 153.622 1.00 56.44  ? 332 PRO   A CA  1 
ATOM   2487 C C   . PRO   A 1 306 ? 124.772 119.924 153.146 1.00 56.15  ? 332 PRO   A C   1 
ATOM   2488 O O   . PRO   A 1 306 ? 124.638 119.062 152.272 1.00 60.77  ? 332 PRO   A O   1 
ATOM   2489 C CB  . PRO   A 1 306 ? 126.458 121.783 153.184 1.00 52.95  ? 332 PRO   A CB  1 
ATOM   2490 C CG  . PRO   A 1 306 ? 127.890 121.797 152.861 1.00 51.52  ? 332 PRO   A CG  1 
ATOM   2491 C CD  . PRO   A 1 306 ? 128.202 120.452 152.318 1.00 56.49  ? 332 PRO   A CD  1 
ATOM   2492 N N   . LEU   A 1 307 ? 123.740 120.535 153.725 1.00 49.21  ? 333 LEU   A N   1 
ATOM   2493 C CA  . LEU   A 1 307 ? 122.368 120.170 153.406 1.00 49.91  ? 333 LEU   A CA  1 
ATOM   2494 C C   . LEU   A 1 307 ? 122.045 120.498 151.954 1.00 55.69  ? 333 LEU   A C   1 
ATOM   2495 O O   . LEU   A 1 307 ? 122.609 121.422 151.361 1.00 54.61  ? 333 LEU   A O   1 
ATOM   2496 C CB  . LEU   A 1 307 ? 121.395 120.899 154.332 1.00 47.05  ? 333 LEU   A CB  1 
ATOM   2497 C CG  . LEU   A 1 307 ? 121.497 120.610 155.829 1.00 50.05  ? 333 LEU   A CG  1 
ATOM   2498 C CD1 . LEU   A 1 307 ? 120.550 121.509 156.596 1.00 46.13  ? 333 LEU   A CD1 1 
ATOM   2499 C CD2 . LEU   A 1 307 ? 121.203 119.148 156.128 1.00 54.32  ? 333 LEU   A CD2 1 
ATOM   2500 N N   . LYS   A 1 308 ? 121.118 119.723 151.386 1.00 60.09  ? 334 LYS   A N   1 
ATOM   2501 C CA  . LYS   A 1 308 ? 120.711 119.845 149.993 1.00 59.75  ? 334 LYS   A CA  1 
ATOM   2502 C C   . LYS   A 1 308 ? 119.252 120.235 149.804 1.00 60.20  ? 334 LYS   A C   1 
ATOM   2503 O O   . LYS   A 1 308 ? 118.846 120.487 148.665 1.00 60.40  ? 334 LYS   A O   1 
ATOM   2504 C CB  . LYS   A 1 308 ? 120.964 118.524 149.250 1.00 63.25  ? 334 LYS   A CB  1 
ATOM   2505 C CG  . LYS   A 1 308 ? 120.335 117.310 149.912 1.00 65.92  ? 334 LYS   A CG  1 
ATOM   2506 C CD  . LYS   A 1 308 ? 120.515 116.063 149.074 1.00 70.48  ? 334 LYS   A CD  1 
ATOM   2507 C CE  . LYS   A 1 308 ? 119.795 114.877 149.689 1.00 77.36  ? 334 LYS   A CE  1 
ATOM   2508 N NZ  . LYS   A 1 308 ? 120.299 114.556 151.053 1.00 79.70  ? 334 LYS   A NZ  1 
ATOM   2509 N N   . ALA   A 1 309 ? 118.455 120.293 150.868 1.00 57.46  ? 335 ALA   A N   1 
ATOM   2510 C CA  . ALA   A 1 309 ? 117.046 120.621 150.742 1.00 51.91  ? 335 ALA   A CA  1 
ATOM   2511 C C   . ALA   A 1 309 ? 116.866 122.111 150.465 1.00 47.29  ? 335 ALA   A C   1 
ATOM   2512 O O   . ALA   A 1 309 ? 117.801 122.908 150.567 1.00 46.75  ? 335 ALA   A O   1 
ATOM   2513 C CB  . ALA   A 1 309 ? 116.290 120.221 152.007 1.00 52.74  ? 335 ALA   A CB  1 
ATOM   2514 N N   . ALA   A 1 310 ? 115.643 122.480 150.103 1.00 45.82  ? 336 ALA   A N   1 
ATOM   2515 C CA  . ALA   A 1 310 ? 115.365 123.858 149.732 1.00 43.49  ? 336 ALA   A CA  1 
ATOM   2516 C C   . ALA   A 1 310 ? 115.556 124.771 150.943 1.00 39.00  ? 336 ALA   A C   1 
ATOM   2517 O O   . ALA   A 1 310 ? 115.199 124.389 152.063 1.00 41.40  ? 336 ALA   A O   1 
ATOM   2518 C CB  . ALA   A 1 310 ? 113.940 123.990 149.197 1.00 43.31  ? 336 ALA   A CB  1 
ATOM   2519 N N   . PRO   A 1 311 ? 116.113 125.973 150.770 1.00 33.62  ? 337 PRO   A N   1 
ATOM   2520 C CA  . PRO   A 1 311 ? 116.339 126.839 151.931 1.00 34.17  ? 337 PRO   A CA  1 
ATOM   2521 C C   . PRO   A 1 311 ? 115.047 127.322 152.568 1.00 35.45  ? 337 PRO   A C   1 
ATOM   2522 O O   . PRO   A 1 311 ? 114.014 127.465 151.912 1.00 37.33  ? 337 PRO   A O   1 
ATOM   2523 C CB  . PRO   A 1 311 ? 117.137 128.011 151.352 1.00 34.26  ? 337 PRO   A CB  1 
ATOM   2524 C CG  . PRO   A 1 311 ? 116.864 127.983 149.919 1.00 36.62  ? 337 PRO   A CG  1 
ATOM   2525 C CD  . PRO   A 1 311 ? 116.695 126.564 149.554 1.00 36.87  ? 337 PRO   A CD  1 
ATOM   2526 N N   . GLN   A 1 312 ? 115.123 127.574 153.877 1.00 34.18  ? 338 GLN   A N   1 
ATOM   2527 C CA  . GLN   A 1 312 ? 114.002 128.085 154.650 1.00 33.84  ? 338 GLN   A CA  1 
ATOM   2528 C C   . GLN   A 1 312 ? 113.929 129.605 154.555 1.00 34.73  ? 338 GLN   A C   1 
ATOM   2529 O O   . GLN   A 1 312 ? 114.925 130.262 154.241 1.00 37.27  ? 338 GLN   A O   1 
ATOM   2530 C CB  . GLN   A 1 312 ? 114.123 127.652 156.112 1.00 34.40  ? 338 GLN   A CB  1 
ATOM   2531 C CG  . GLN   A 1 312 ? 115.409 128.067 156.822 1.00 35.33  ? 338 GLN   A CG  1 
ATOM   2532 C CD  . GLN   A 1 312 ? 115.311 127.942 158.329 1.00 36.80  ? 338 GLN   A CD  1 
ATOM   2533 O OE1 . GLN   A 1 312 ? 114.309 127.475 158.865 1.00 35.29  ? 338 GLN   A OE1 1 
ATOM   2534 N NE2 . GLN   A 1 312 ? 116.358 128.367 159.023 1.00 43.23  ? 338 GLN   A NE2 1 
ATOM   2535 N N   . PRO   A 1 313 ? 112.764 130.206 154.809 1.00 32.30  ? 339 PRO   A N   1 
ATOM   2536 C CA  . PRO   A 1 313 ? 112.660 131.664 154.691 1.00 32.24  ? 339 PRO   A CA  1 
ATOM   2537 C C   . PRO   A 1 313 ? 113.515 132.387 155.717 1.00 36.48  ? 339 PRO   A C   1 
ATOM   2538 O O   . PRO   A 1 313 ? 113.723 131.913 156.836 1.00 41.25  ? 339 PRO   A O   1 
ATOM   2539 C CB  . PRO   A 1 313 ? 111.171 131.941 154.935 1.00 33.35  ? 339 PRO   A CB  1 
ATOM   2540 C CG  . PRO   A 1 313 ? 110.496 130.649 154.818 1.00 33.00  ? 339 PRO   A CG  1 
ATOM   2541 C CD  . PRO   A 1 313 ? 111.480 129.617 155.222 1.00 33.81  ? 339 PRO   A CD  1 
ATOM   2542 N N   . SER   A 1 314 ? 114.014 133.550 155.314 1.00 35.37  ? 340 SER   A N   1 
ATOM   2543 C CA  . SER   A 1 314 ? 114.743 134.465 156.177 1.00 36.34  ? 340 SER   A CA  1 
ATOM   2544 C C   . SER   A 1 314 ? 113.976 135.774 156.283 1.00 38.26  ? 340 SER   A C   1 
ATOM   2545 O O   . SER   A 1 314 ? 113.069 136.056 155.496 1.00 41.37  ? 340 SER   A O   1 
ATOM   2546 C CB  . SER   A 1 314 ? 116.156 134.719 155.644 1.00 42.10  ? 340 SER   A CB  1 
ATOM   2547 O OG  . SER   A 1 314 ? 116.867 135.607 156.488 1.00 47.19  ? 340 SER   A OG  1 
ATOM   2548 N N   . VAL   A 1 315 ? 114.357 136.581 157.273 1.00 40.86  ? 341 VAL   A N   1 
ATOM   2549 C CA  . VAL   A 1 315 ? 113.756 137.891 157.494 1.00 40.83  ? 341 VAL   A CA  1 
ATOM   2550 C C   . VAL   A 1 315 ? 114.570 139.005 156.840 1.00 43.90  ? 341 VAL   A C   1 
ATOM   2551 O O   . VAL   A 1 315 ? 114.238 140.182 156.999 1.00 48.93  ? 341 VAL   A O   1 
ATOM   2552 C CB  . VAL   A 1 315 ? 113.567 138.153 158.999 1.00 46.66  ? 341 VAL   A CB  1 
ATOM   2553 C CG1 . VAL   A 1 315 ? 114.901 138.494 159.664 1.00 50.55  ? 341 VAL   A CG1 1 
ATOM   2554 C CG2 . VAL   A 1 315 ? 112.523 139.244 159.251 1.00 46.14  ? 341 VAL   A CG2 1 
ATOM   2555 N N   . SER   A 1 316 ? 115.622 138.661 156.092 1.00 43.10  ? 342 SER   A N   1 
ATOM   2556 C CA  . SER   A 1 316 ? 116.398 139.620 155.318 1.00 47.13  ? 342 SER   A CA  1 
ATOM   2557 C C   . SER   A 1 316 ? 115.947 139.676 153.861 1.00 45.84  ? 342 SER   A C   1 
ATOM   2558 O O   . SER   A 1 316 ? 116.752 139.974 152.973 1.00 44.12  ? 342 SER   A O   1 
ATOM   2559 C CB  . SER   A 1 316 ? 117.883 139.274 155.402 1.00 48.53  ? 342 SER   A CB  1 
ATOM   2560 O OG  . SER   A 1 316 ? 118.133 137.978 154.886 1.00 46.61  ? 342 SER   A OG  1 
ATOM   2561 N N   . CYS   A 1 317 ? 114.671 139.394 153.602 1.00 40.83  ? 343 CYS   A N   1 
ATOM   2562 C CA  . CYS   A 1 317 ? 114.120 139.383 152.256 1.00 37.47  ? 343 CYS   A CA  1 
ATOM   2563 C C   . CYS   A 1 317 ? 112.684 139.884 152.299 1.00 41.86  ? 343 CYS   A C   1 
ATOM   2564 O O   . CYS   A 1 317 ? 112.032 139.866 153.345 1.00 44.97  ? 343 CYS   A O   1 
ATOM   2565 C CB  . CYS   A 1 317 ? 114.158 137.978 151.640 1.00 39.11  ? 343 CYS   A CB  1 
ATOM   2566 S SG  . CYS   A 1 317 ? 115.791 137.235 151.518 1.00 46.28  ? 343 CYS   A SG  1 
ATOM   2567 N N   . VAL   A 1 318 ? 112.199 140.332 151.143 1.00 40.54  ? 344 VAL   A N   1 
ATOM   2568 C CA  . VAL   A 1 318 ? 110.810 140.742 150.952 1.00 39.69  ? 344 VAL   A CA  1 
ATOM   2569 C C   . VAL   A 1 318 ? 110.159 139.760 149.990 1.00 41.87  ? 344 VAL   A C   1 
ATOM   2570 O O   . VAL   A 1 318 ? 110.660 139.547 148.881 1.00 43.50  ? 344 VAL   A O   1 
ATOM   2571 C CB  . VAL   A 1 318 ? 110.714 142.182 150.418 1.00 45.48  ? 344 VAL   A CB  1 
ATOM   2572 C CG1 . VAL   A 1 318 ? 109.259 142.630 150.343 1.00 50.20  ? 344 VAL   A CG1 1 
ATOM   2573 C CG2 . VAL   A 1 318 ? 111.529 143.127 151.287 1.00 46.83  ? 344 VAL   A CG2 1 
ATOM   2574 N N   . TYR   A 1 319 ? 109.045 139.167 150.414 1.00 43.24  ? 345 TYR   A N   1 
ATOM   2575 C CA  . TYR   A 1 319 ? 108.346 138.139 149.654 1.00 43.61  ? 345 TYR   A CA  1 
ATOM   2576 C C   . TYR   A 1 319 ? 107.063 138.709 149.067 1.00 53.14  ? 345 TYR   A C   1 
ATOM   2577 O O   . TYR   A 1 319 ? 106.347 139.462 149.732 1.00 59.47  ? 345 TYR   A O   1 
ATOM   2578 C CB  . TYR   A 1 319 ? 108.011 136.936 150.539 1.00 43.15  ? 345 TYR   A CB  1 
ATOM   2579 C CG  . TYR   A 1 319 ? 109.203 136.344 151.255 1.00 41.34  ? 345 TYR   A CG  1 
ATOM   2580 C CD1 . TYR   A 1 319 ? 109.581 136.802 152.506 1.00 42.35  ? 345 TYR   A CD1 1 
ATOM   2581 C CD2 . TYR   A 1 319 ? 109.947 135.328 150.682 1.00 38.00  ? 345 TYR   A CD2 1 
ATOM   2582 C CE1 . TYR   A 1 319 ? 110.664 136.271 153.161 1.00 37.75  ? 345 TYR   A CE1 1 
ATOM   2583 C CE2 . TYR   A 1 319 ? 111.030 134.790 151.331 1.00 34.72  ? 345 TYR   A CE2 1 
ATOM   2584 C CZ  . TYR   A 1 319 ? 111.385 135.267 152.570 1.00 38.02  ? 345 TYR   A CZ  1 
ATOM   2585 O OH  . TYR   A 1 319 ? 112.467 134.735 153.227 1.00 49.06  ? 345 TYR   A OH  1 
ATOM   2586 N N   . LYS   A 1 320 ? 106.777 138.342 147.822 1.00 60.40  ? 346 LYS   A N   1 
ATOM   2587 C CA  . LYS   A 1 320 ? 105.563 138.759 147.134 1.00 61.01  ? 346 LYS   A CA  1 
ATOM   2588 C C   . LYS   A 1 320 ? 104.505 137.678 147.293 1.00 64.28  ? 346 LYS   A C   1 
ATOM   2589 O O   . LYS   A 1 320 ? 104.721 136.530 146.892 1.00 69.78  ? 346 LYS   A O   1 
ATOM   2590 C CB  . LYS   A 1 320 ? 105.832 139.010 145.651 1.00 65.95  ? 346 LYS   A CB  1 
ATOM   2591 C CG  . LYS   A 1 320 ? 106.873 140.077 145.368 1.00 70.25  ? 346 LYS   A CG  1 
ATOM   2592 C CD  . LYS   A 1 320 ? 107.052 140.279 143.872 1.00 72.93  ? 346 LYS   A CD  1 
ATOM   2593 C CE  . LYS   A 1 320 ? 108.134 141.299 143.569 1.00 74.77  ? 346 LYS   A CE  1 
ATOM   2594 N NZ  . LYS   A 1 320 ? 108.308 141.515 142.106 1.00 73.85  ? 346 LYS   A NZ  1 
ATOM   2595 N N   . ARG   A 1 321 ? 103.364 138.048 147.862 1.00 69.59  ? 347 ARG   A N   1 
ATOM   2596 C CA  . ARG   A 1 321 ? 102.273 137.108 148.080 1.00 74.90  ? 347 ARG   A CA  1 
ATOM   2597 C C   . ARG   A 1 321 ? 101.348 137.075 146.870 1.00 74.54  ? 347 ARG   A C   1 
ATOM   2598 O O   . ARG   A 1 321 ? 101.129 138.097 146.218 1.00 74.14  ? 347 ARG   A O   1 
ATOM   2599 C CB  . ARG   A 1 321 ? 101.485 137.481 149.335 1.00 81.04  ? 347 ARG   A CB  1 
ATOM   2600 C CG  . ARG   A 1 321 ? 102.299 137.418 150.618 1.00 82.73  ? 347 ARG   A CG  1 
ATOM   2601 C CD  . ARG   A 1 321 ? 101.474 137.829 151.829 1.00 87.77  ? 347 ARG   A CD  1 
ATOM   2602 N NE  . ARG   A 1 321 ? 100.364 136.915 152.080 1.00 92.71  ? 347 ARG   A NE  1 
ATOM   2603 C CZ  . ARG   A 1 321 ? 99.485  137.040 153.067 1.00 92.71  ? 347 ARG   A CZ  1 
ATOM   2604 N NH1 . ARG   A 1 321 ? 99.544  138.043 153.931 1.00 91.07  ? 347 ARG   A NH1 1 
ATOM   2605 N NH2 . ARG   A 1 321 ? 98.519  136.135 153.192 1.00 93.49  ? 347 ARG   A NH2 1 
ATOM   2606 N N   . GLY   A 1 327 ? 101.260 141.955 150.502 1.00 66.05  ? 353 GLY   A N   1 
ATOM   2607 C CA  . GLY   A 1 327 ? 102.517 141.231 150.483 1.00 70.46  ? 353 GLY   A CA  1 
ATOM   2608 C C   . GLY   A 1 327 ? 103.335 141.455 151.739 1.00 71.47  ? 353 GLY   A C   1 
ATOM   2609 O O   . GLY   A 1 327 ? 103.030 140.909 152.797 1.00 69.64  ? 353 GLY   A O   1 
ATOM   2610 N N   . GLN   A 1 328 ? 104.388 142.261 151.613 1.00 70.89  ? 354 GLN   A N   1 
ATOM   2611 C CA  . GLN   A 1 328 ? 105.227 142.622 152.752 1.00 66.23  ? 354 GLN   A CA  1 
ATOM   2612 C C   . GLN   A 1 328 ? 105.859 143.971 152.445 1.00 63.60  ? 354 GLN   A C   1 
ATOM   2613 O O   . GLN   A 1 328 ? 106.751 144.057 151.597 1.00 62.29  ? 354 GLN   A O   1 
ATOM   2614 C CB  . GLN   A 1 328 ? 106.292 141.561 153.014 1.00 60.47  ? 354 GLN   A CB  1 
ATOM   2615 C CG  . GLN   A 1 328 ? 107.168 141.842 154.221 1.00 60.67  ? 354 GLN   A CG  1 
ATOM   2616 C CD  . GLN   A 1 328 ? 108.143 140.721 154.503 1.00 64.12  ? 354 GLN   A CD  1 
ATOM   2617 O OE1 . GLN   A 1 328 ? 108.134 139.692 153.829 1.00 61.46  ? 354 GLN   A OE1 1 
ATOM   2618 N NE2 . GLN   A 1 328 ? 108.993 140.915 155.503 1.00 62.75  ? 354 GLN   A NE2 1 
ATOM   2619 N N   . LYS   A 1 329 ? 105.393 145.013 153.121 1.00 59.00  ? 355 LYS   A N   1 
ATOM   2620 C CA  . LYS   A 1 329 ? 105.953 146.337 152.911 1.00 59.62  ? 355 LYS   A CA  1 
ATOM   2621 C C   . LYS   A 1 329 ? 107.425 146.337 153.332 1.00 59.37  ? 355 LYS   A C   1 
ATOM   2622 O O   . LYS   A 1 329 ? 107.765 145.738 154.360 1.00 61.50  ? 355 LYS   A O   1 
ATOM   2623 C CB  . LYS   A 1 329 ? 105.168 147.372 153.716 1.00 62.18  ? 355 LYS   A CB  1 
ATOM   2624 C CG  . LYS   A 1 329 ? 105.327 148.807 153.238 1.00 64.14  ? 355 LYS   A CG  1 
ATOM   2625 C CD  . LYS   A 1 329 ? 106.210 149.624 154.163 1.00 62.93  ? 355 LYS   A CD  1 
ATOM   2626 C CE  . LYS   A 1 329 ? 105.499 150.021 155.453 1.00 66.12  ? 355 LYS   A CE  1 
ATOM   2627 N NZ  . LYS   A 1 329 ? 104.340 150.925 155.223 1.00 67.92  ? 355 LYS   A NZ  1 
ATOM   2628 N N   . PRO   A 1 330 ? 108.330 146.964 152.566 1.00 53.11  ? 356 PRO   A N   1 
ATOM   2629 C CA  . PRO   A 1 330 ? 109.747 146.922 152.950 1.00 49.97  ? 356 PRO   A CA  1 
ATOM   2630 C C   . PRO   A 1 330 ? 109.998 147.582 154.296 1.00 48.17  ? 356 PRO   A C   1 
ATOM   2631 O O   . PRO   A 1 330 ? 109.389 148.597 154.638 1.00 52.21  ? 356 PRO   A O   1 
ATOM   2632 C CB  . PRO   A 1 330 ? 110.444 147.685 151.820 1.00 46.10  ? 356 PRO   A CB  1 
ATOM   2633 C CG  . PRO   A 1 330 ? 109.544 147.600 150.692 1.00 47.69  ? 356 PRO   A CG  1 
ATOM   2634 C CD  . PRO   A 1 330 ? 108.169 147.619 151.255 1.00 51.94  ? 356 PRO   A CD  1 
ATOM   2635 N N   . GLY   A 1 331 ? 110.915 146.997 155.056 1.00 43.49  ? 357 GLY   A N   1 
ATOM   2636 C CA  . GLY   A 1 331 ? 111.297 147.558 156.334 1.00 44.65  ? 357 GLY   A CA  1 
ATOM   2637 C C   . GLY   A 1 331 ? 112.358 148.621 156.173 1.00 44.75  ? 357 GLY   A C   1 
ATOM   2638 O O   . GLY   A 1 331 ? 112.343 149.371 155.193 1.00 45.73  ? 357 GLY   A O   1 
ATOM   2639 N N   . LEU   A 1 332 ? 113.290 148.688 157.121 1.00 43.66  ? 358 LEU   A N   1 
ATOM   2640 C CA  . LEU   A 1 332 ? 114.376 149.658 157.089 1.00 43.17  ? 358 LEU   A CA  1 
ATOM   2641 C C   . LEU   A 1 332 ? 115.673 149.074 156.554 1.00 44.32  ? 358 LEU   A C   1 
ATOM   2642 O O   . LEU   A 1 332 ? 116.376 149.746 155.795 1.00 50.33  ? 358 LEU   A O   1 
ATOM   2643 C CB  . LEU   A 1 332 ? 114.620 150.226 158.491 1.00 43.39  ? 358 LEU   A CB  1 
ATOM   2644 C CG  . LEU   A 1 332 ? 115.602 151.399 158.601 1.00 45.77  ? 358 LEU   A CG  1 
ATOM   2645 C CD1 . LEU   A 1 332 ? 115.086 152.625 157.875 1.00 45.08  ? 358 LEU   A CD1 1 
ATOM   2646 C CD2 . LEU   A 1 332 ? 115.872 151.723 160.058 1.00 46.09  ? 358 LEU   A CD2 1 
ATOM   2647 N N   . ARG   A 1 333 ? 116.017 147.842 156.932 1.00 39.02  ? 359 ARG   A N   1 
ATOM   2648 C CA  . ARG   A 1 333 ? 117.283 147.280 156.482 1.00 41.63  ? 359 ARG   A CA  1 
ATOM   2649 C C   . ARG   A 1 333 ? 117.288 147.038 154.979 1.00 43.48  ? 359 ARG   A C   1 
ATOM   2650 O O   . ARG   A 1 333 ? 118.350 147.088 154.351 1.00 45.84  ? 359 ARG   A O   1 
ATOM   2651 C CB  . ARG   A 1 333 ? 117.596 145.989 157.237 1.00 48.76  ? 359 ARG   A CB  1 
ATOM   2652 C CG  . ARG   A 1 333 ? 116.625 144.845 157.008 1.00 53.26  ? 359 ARG   A CG  1 
ATOM   2653 C CD  . ARG   A 1 333 ? 116.988 143.642 157.868 1.00 54.72  ? 359 ARG   A CD  1 
ATOM   2654 N NE  . ARG   A 1 333 ? 118.343 143.168 157.608 1.00 54.42  ? 359 ARG   A NE  1 
ATOM   2655 C CZ  . ARG   A 1 333 ? 118.939 142.178 158.261 1.00 58.12  ? 359 ARG   A CZ  1 
ATOM   2656 N NH1 . ARG   A 1 333 ? 118.328 141.515 159.232 1.00 62.07  ? 359 ARG   A NH1 1 
ATOM   2657 N NH2 . ARG   A 1 333 ? 120.182 141.841 157.931 1.00 58.28  ? 359 ARG   A NH2 1 
ATOM   2658 N N   . HIS   A 1 334 ? 116.123 146.779 154.385 1.00 42.82  ? 360 HIS   A N   1 
ATOM   2659 C CA  . HIS   A 1 334 ? 116.055 146.616 152.936 1.00 46.90  ? 360 HIS   A CA  1 
ATOM   2660 C C   . HIS   A 1 334 ? 116.397 147.920 152.220 1.00 49.52  ? 360 HIS   A C   1 
ATOM   2661 O O   . HIS   A 1 334 ? 117.172 147.930 151.249 1.00 50.50  ? 360 HIS   A O   1 
ATOM   2662 C CB  . HIS   A 1 334 ? 114.661 146.130 152.539 1.00 46.78  ? 360 HIS   A CB  1 
ATOM   2663 C CG  . HIS   A 1 334 ? 114.218 144.900 153.272 1.00 47.75  ? 360 HIS   A CG  1 
ATOM   2664 N ND1 . HIS   A 1 334 ? 113.395 144.950 154.376 1.00 46.02  ? 360 HIS   A ND1 1 
ATOM   2665 C CD2 . HIS   A 1 334 ? 114.496 143.591 153.071 1.00 49.55  ? 360 HIS   A CD2 1 
ATOM   2666 C CE1 . HIS   A 1 334 ? 113.178 143.725 154.819 1.00 42.46  ? 360 HIS   A CE1 1 
ATOM   2667 N NE2 . HIS   A 1 334 ? 113.834 142.882 154.045 1.00 49.21  ? 360 HIS   A NE2 1 
ATOM   2668 N N   . GLN   A 1 335 ? 115.834 149.034 152.694 1.00 44.23  ? 361 GLN   A N   1 
ATOM   2669 C CA  . GLN   A 1 335 ? 116.135 150.331 152.104 1.00 41.83  ? 361 GLN   A CA  1 
ATOM   2670 C C   . GLN   A 1 335 ? 117.607 150.675 152.266 1.00 42.05  ? 361 GLN   A C   1 
ATOM   2671 O O   . GLN   A 1 335 ? 118.243 151.183 151.333 1.00 45.11  ? 361 GLN   A O   1 
ATOM   2672 C CB  . GLN   A 1 335 ? 115.263 151.409 152.746 1.00 41.66  ? 361 GLN   A CB  1 
ATOM   2673 C CG  . GLN   A 1 335 ? 113.774 151.187 152.582 1.00 43.85  ? 361 GLN   A CG  1 
ATOM   2674 C CD  . GLN   A 1 335 ? 112.955 152.302 153.184 1.00 45.75  ? 361 GLN   A CD  1 
ATOM   2675 O OE1 . GLN   A 1 335 ? 113.499 153.294 153.666 1.00 52.01  ? 361 GLN   A OE1 1 
ATOM   2676 N NE2 . GLN   A 1 335 ? 111.638 152.150 153.163 1.00 41.91  ? 361 GLN   A NE2 1 
ATOM   2677 N N   . LEU   A 1 336 ? 118.164 150.412 153.448 1.00 40.02  ? 362 LEU   A N   1 
ATOM   2678 C CA  . LEU   A 1 336 ? 119.578 150.677 153.668 1.00 38.41  ? 362 LEU   A CA  1 
ATOM   2679 C C   . LEU   A 1 336 ? 120.443 149.813 152.763 1.00 40.84  ? 362 LEU   A C   1 
ATOM   2680 O O   . LEU   A 1 336 ? 121.475 150.271 152.267 1.00 47.65  ? 362 LEU   A O   1 
ATOM   2681 C CB  . LEU   A 1 336 ? 119.940 150.447 155.134 1.00 35.93  ? 362 LEU   A CB  1 
ATOM   2682 C CG  . LEU   A 1 336 ? 119.333 151.393 156.167 1.00 34.87  ? 362 LEU   A CG  1 
ATOM   2683 C CD1 . LEU   A 1 336 ? 119.756 150.980 157.560 1.00 38.91  ? 362 LEU   A CD1 1 
ATOM   2684 C CD2 . LEU   A 1 336 ? 119.734 152.829 155.907 1.00 38.54  ? 362 LEU   A CD2 1 
ATOM   2685 N N   . GLY   A 1 337 ? 120.041 148.565 152.535 1.00 37.16  ? 363 GLY   A N   1 
ATOM   2686 C CA  . GLY   A 1 337 ? 120.796 147.717 151.630 1.00 40.95  ? 363 GLY   A CA  1 
ATOM   2687 C C   . GLY   A 1 337 ? 120.805 148.250 150.212 1.00 42.64  ? 363 GLY   A C   1 
ATOM   2688 O O   . GLY   A 1 337 ? 121.854 148.292 149.558 1.00 44.90  ? 363 GLY   A O   1 
ATOM   2689 N N   . ALA   A 1 338 ? 119.640 148.676 149.719 1.00 39.58  ? 364 ALA   A N   1 
ATOM   2690 C CA  . ALA   A 1 338 ? 119.583 149.233 148.371 1.00 41.05  ? 364 ALA   A CA  1 
ATOM   2691 C C   . ALA   A 1 338 ? 120.425 150.499 148.260 1.00 45.08  ? 364 ALA   A C   1 
ATOM   2692 O O   . ALA   A 1 338 ? 121.188 150.672 147.295 1.00 48.05  ? 364 ALA   A O   1 
ATOM   2693 C CB  . ALA   A 1 338 ? 118.133 149.519 147.986 1.00 43.61  ? 364 ALA   A CB  1 
ATOM   2694 N N   . ALA   A 1 339 ? 120.310 151.392 149.248 1.00 43.82  ? 365 ALA   A N   1 
ATOM   2695 C CA  . ALA   A 1 339 ? 121.087 152.626 149.223 1.00 40.71  ? 365 ALA   A CA  1 
ATOM   2696 C C   . ALA   A 1 339 ? 122.579 152.337 149.282 1.00 42.61  ? 365 ALA   A C   1 
ATOM   2697 O O   . ALA   A 1 339 ? 123.370 152.974 148.575 1.00 47.20  ? 365 ALA   A O   1 
ATOM   2698 C CB  . ALA   A 1 339 ? 120.673 153.528 150.384 1.00 39.15  ? 365 ALA   A CB  1 
ATOM   2699 N N   . PHE   A 1 340 ? 122.982 151.377 150.117 1.00 41.21  ? 366 PHE   A N   1 
ATOM   2700 C CA  . PHE   A 1 340 ? 124.386 151.005 150.201 1.00 41.63  ? 366 PHE   A CA  1 
ATOM   2701 C C   . PHE   A 1 340 ? 124.894 150.490 148.867 1.00 42.85  ? 366 PHE   A C   1 
ATOM   2702 O O   . PHE   A 1 340 ? 125.972 150.890 148.417 1.00 48.89  ? 366 PHE   A O   1 
ATOM   2703 C CB  . PHE   A 1 340 ? 124.587 149.951 151.287 1.00 42.26  ? 366 PHE   A CB  1 
ATOM   2704 C CG  . PHE   A 1 340 ? 125.970 149.375 151.322 1.00 43.57  ? 366 PHE   A CG  1 
ATOM   2705 C CD1 . PHE   A 1 340 ? 127.017 150.088 151.870 1.00 47.68  ? 366 PHE   A CD1 1 
ATOM   2706 C CD2 . PHE   A 1 340 ? 126.222 148.117 150.813 1.00 44.42  ? 366 PHE   A CD2 1 
ATOM   2707 C CE1 . PHE   A 1 340 ? 128.288 149.556 151.904 1.00 48.59  ? 366 PHE   A CE1 1 
ATOM   2708 C CE2 . PHE   A 1 340 ? 127.489 147.584 150.846 1.00 47.91  ? 366 PHE   A CE2 1 
ATOM   2709 C CZ  . PHE   A 1 340 ? 128.521 148.302 151.392 1.00 46.51  ? 366 PHE   A CZ  1 
ATOM   2710 N N   . THR   A 1 341 ? 124.122 149.621 148.209 1.00 39.82  ? 367 THR   A N   1 
ATOM   2711 C CA  . THR   A 1 341 ? 124.546 149.090 146.917 1.00 41.84  ? 367 THR   A CA  1 
ATOM   2712 C C   . THR   A 1 341 ? 124.766 150.214 145.910 1.00 46.30  ? 367 THR   A C   1 
ATOM   2713 O O   . THR   A 1 341 ? 125.848 150.327 145.308 1.00 48.45  ? 367 THR   A O   1 
ATOM   2714 C CB  . THR   A 1 341 ? 123.506 148.099 146.395 1.00 41.18  ? 367 THR   A CB  1 
ATOM   2715 O OG1 . THR   A 1 341 ? 123.303 147.060 147.360 1.00 42.59  ? 367 THR   A OG1 1 
ATOM   2716 C CG2 . THR   A 1 341 ? 123.955 147.484 145.083 1.00 41.10  ? 367 THR   A CG2 1 
ATOM   2717 N N   . LEU   A 1 342 ? 123.762 151.081 145.747 1.00 45.19  ? 368 LEU   A N   1 
ATOM   2718 C CA  . LEU   A 1 342 ? 123.857 152.136 144.739 1.00 41.16  ? 368 LEU   A CA  1 
ATOM   2719 C C   . LEU   A 1 342 ? 125.006 153.092 145.041 1.00 42.95  ? 368 LEU   A C   1 
ATOM   2720 O O   . LEU   A 1 342 ? 125.850 153.363 144.174 1.00 50.80  ? 368 LEU   A O   1 
ATOM   2721 C CB  . LEU   A 1 342 ? 122.537 152.902 144.650 1.00 42.49  ? 368 LEU   A CB  1 
ATOM   2722 C CG  . LEU   A 1 342 ? 121.278 152.113 144.287 1.00 50.41  ? 368 LEU   A CG  1 
ATOM   2723 C CD1 . LEU   A 1 342 ? 120.066 153.025 144.309 1.00 51.05  ? 368 LEU   A CD1 1 
ATOM   2724 C CD2 . LEU   A 1 342 ? 121.406 151.442 142.938 1.00 51.40  ? 368 LEU   A CD2 1 
ATOM   2725 N N   . LEU   A 1 343 ? 125.062 153.607 146.272 1.00 40.87  ? 369 LEU   A N   1 
ATOM   2726 C CA  . LEU   A 1 343 ? 126.082 154.591 146.612 1.00 40.62  ? 369 LEU   A CA  1 
ATOM   2727 C C   . LEU   A 1 343 ? 127.481 153.994 146.536 1.00 42.26  ? 369 LEU   A C   1 
ATOM   2728 O O   . LEU   A 1 343 ? 128.412 154.651 146.054 1.00 46.63  ? 369 LEU   A O   1 
ATOM   2729 C CB  . LEU   A 1 343 ? 125.815 155.165 148.003 1.00 40.60  ? 369 LEU   A CB  1 
ATOM   2730 C CG  . LEU   A 1 343 ? 124.902 156.393 148.056 1.00 43.09  ? 369 LEU   A CG  1 
ATOM   2731 C CD1 . LEU   A 1 343 ? 123.505 156.102 147.522 1.00 42.85  ? 369 LEU   A CD1 1 
ATOM   2732 C CD2 . LEU   A 1 343 ? 124.827 156.919 149.476 1.00 42.79  ? 369 LEU   A CD2 1 
ATOM   2733 N N   . TYR   A 1 344 ? 127.656 152.755 147.001 1.00 37.18  ? 370 TYR   A N   1 
ATOM   2734 C CA  . TYR   A 1 344 ? 128.974 152.140 146.969 1.00 38.21  ? 370 TYR   A CA  1 
ATOM   2735 C C   . TYR   A 1 344 ? 129.452 151.931 145.542 1.00 44.63  ? 370 TYR   A C   1 
ATOM   2736 O O   . TYR   A 1 344 ? 130.621 152.195 145.236 1.00 50.03  ? 370 TYR   A O   1 
ATOM   2737 C CB  . TYR   A 1 344 ? 128.944 150.816 147.725 1.00 42.50  ? 370 TYR   A CB  1 
ATOM   2738 C CG  . TYR   A 1 344 ? 130.268 150.093 147.766 1.00 46.58  ? 370 TYR   A CG  1 
ATOM   2739 C CD1 . TYR   A 1 344 ? 131.239 150.435 148.693 1.00 44.93  ? 370 TYR   A CD1 1 
ATOM   2740 C CD2 . TYR   A 1 344 ? 130.539 149.058 146.890 1.00 47.77  ? 370 TYR   A CD2 1 
ATOM   2741 C CE1 . TYR   A 1 344 ? 132.441 149.773 148.737 1.00 40.71  ? 370 TYR   A CE1 1 
ATOM   2742 C CE2 . TYR   A 1 344 ? 131.739 148.392 146.928 1.00 49.14  ? 370 TYR   A CE2 1 
ATOM   2743 C CZ  . TYR   A 1 344 ? 132.687 148.755 147.852 1.00 45.77  ? 370 TYR   A CZ  1 
ATOM   2744 O OH  . TYR   A 1 344 ? 133.887 148.088 147.892 1.00 49.27  ? 370 TYR   A OH  1 
ATOM   2745 N N   . LEU   A 1 345 ? 128.579 151.461 144.646 1.00 45.87  ? 371 LEU   A N   1 
ATOM   2746 C CA  . LEU   A 1 345 ? 129.034 151.253 143.274 1.00 44.73  ? 371 LEU   A CA  1 
ATOM   2747 C C   . LEU   A 1 345 ? 129.310 152.580 142.575 1.00 43.19  ? 371 LEU   A C   1 
ATOM   2748 O O   . LEU   A 1 345 ? 130.250 152.681 141.774 1.00 47.23  ? 371 LEU   A O   1 
ATOM   2749 C CB  . LEU   A 1 345 ? 128.020 150.418 142.494 1.00 46.76  ? 371 LEU   A CB  1 
ATOM   2750 C CG  . LEU   A 1 345 ? 127.917 148.937 142.891 1.00 47.77  ? 371 LEU   A CG  1 
ATOM   2751 C CD1 . LEU   A 1 345 ? 126.839 148.231 142.088 1.00 49.63  ? 371 LEU   A CD1 1 
ATOM   2752 C CD2 . LEU   A 1 345 ? 129.241 148.204 142.722 1.00 44.84  ? 371 LEU   A CD2 1 
ATOM   2753 N N   . LEU   A 1 346 ? 128.525 153.619 142.875 1.00 40.78  ? 372 LEU   A N   1 
ATOM   2754 C CA  . LEU   A 1 346 ? 128.829 154.932 142.310 1.00 41.73  ? 372 LEU   A CA  1 
ATOM   2755 C C   . LEU   A 1 346 ? 130.184 155.434 142.792 1.00 45.45  ? 372 LEU   A C   1 
ATOM   2756 O O   . LEU   A 1 346 ? 130.981 155.958 142.001 1.00 45.59  ? 372 LEU   A O   1 
ATOM   2757 C CB  . LEU   A 1 346 ? 127.733 155.936 142.663 1.00 39.19  ? 372 LEU   A CB  1 
ATOM   2758 C CG  . LEU   A 1 346 ? 126.678 156.176 141.582 1.00 40.33  ? 372 LEU   A CG  1 
ATOM   2759 C CD1 . LEU   A 1 346 ? 125.845 154.932 141.321 1.00 44.70  ? 372 LEU   A CD1 1 
ATOM   2760 C CD2 . LEU   A 1 346 ? 125.788 157.340 141.971 1.00 41.96  ? 372 LEU   A CD2 1 
ATOM   2761 N N   . GLU   A 1 347 ? 130.469 155.273 144.085 1.00 44.59  ? 373 GLU   A N   1 
ATOM   2762 C CA  . GLU   A 1 347 ? 131.761 155.697 144.612 1.00 42.69  ? 373 GLU   A CA  1 
ATOM   2763 C C   . GLU   A 1 347 ? 132.895 154.894 143.991 1.00 42.11  ? 373 GLU   A C   1 
ATOM   2764 O O   . GLU   A 1 347 ? 133.980 155.430 143.739 1.00 46.51  ? 373 GLU   A O   1 
ATOM   2765 C CB  . GLU   A 1 347 ? 131.771 155.567 146.134 1.00 41.36  ? 373 GLU   A CB  1 
ATOM   2766 C CG  . GLU   A 1 347 ? 133.087 155.954 146.786 1.00 39.96  ? 373 GLU   A CG  1 
ATOM   2767 C CD  . GLU   A 1 347 ? 133.987 154.772 147.097 1.00 46.05  ? 373 GLU   A CD  1 
ATOM   2768 O OE1 . GLU   A 1 347 ? 133.798 153.684 146.517 1.00 46.64  ? 373 GLU   A OE1 1 
ATOM   2769 O OE2 . GLU   A 1 347 ? 134.897 154.933 147.936 1.00 54.61  ? 373 GLU   A OE2 1 
ATOM   2770 N N   . GLN   A 1 348 ? 132.669 153.602 143.755 1.00 42.19  ? 374 GLN   A N   1 
ATOM   2771 C CA  . GLN   A 1 348 ? 133.696 152.778 143.130 1.00 44.30  ? 374 GLN   A CA  1 
ATOM   2772 C C   . GLN   A 1 348 ? 133.984 153.239 141.711 1.00 48.21  ? 374 GLN   A C   1 
ATOM   2773 O O   . GLN   A 1 348 ? 135.141 153.256 141.280 1.00 50.04  ? 374 GLN   A O   1 
ATOM   2774 C CB  . GLN   A 1 348 ? 133.274 151.310 143.135 1.00 45.39  ? 374 GLN   A CB  1 
ATOM   2775 C CG  . GLN   A 1 348 ? 133.526 150.596 144.438 1.00 45.76  ? 374 GLN   A CG  1 
ATOM   2776 C CD  . GLN   A 1 348 ? 134.996 150.389 144.702 1.00 48.26  ? 374 GLN   A CD  1 
ATOM   2777 O OE1 . GLN   A 1 348 ? 135.606 149.461 144.178 1.00 53.12  ? 374 GLN   A OE1 1 
ATOM   2778 N NE2 . GLN   A 1 348 ? 135.579 151.262 145.511 1.00 50.78  ? 374 GLN   A NE2 1 
ATOM   2779 N N   . LEU   A 1 349 ? 132.944 153.601 140.963 1.00 48.02  ? 375 LEU   A N   1 
ATOM   2780 C CA  . LEU   A 1 349 ? 133.175 154.143 139.628 1.00 45.54  ? 375 LEU   A CA  1 
ATOM   2781 C C   . LEU   A 1 349 ? 133.921 155.471 139.696 1.00 44.91  ? 375 LEU   A C   1 
ATOM   2782 O O   . LEU   A 1 349 ? 134.794 155.742 138.865 1.00 42.63  ? 375 LEU   A O   1 
ATOM   2783 C CB  . LEU   A 1 349 ? 131.849 154.317 138.886 1.00 47.39  ? 375 LEU   A CB  1 
ATOM   2784 C CG  . LEU   A 1 349 ? 131.133 153.057 138.397 1.00 51.57  ? 375 LEU   A CG  1 
ATOM   2785 C CD1 . LEU   A 1 349 ? 129.774 153.421 137.830 1.00 49.33  ? 375 LEU   A CD1 1 
ATOM   2786 C CD2 . LEU   A 1 349 ? 131.957 152.314 137.357 1.00 53.04  ? 375 LEU   A CD2 1 
ATOM   2787 N N   . PHE   A 1 350 ? 133.594 156.312 140.680 1.00 44.92  ? 376 PHE   A N   1 
ATOM   2788 C CA  . PHE   A 1 350 ? 134.157 157.660 140.710 1.00 38.55  ? 376 PHE   A CA  1 
ATOM   2789 C C   . PHE   A 1 350 ? 135.604 157.689 141.191 1.00 43.66  ? 376 PHE   A C   1 
ATOM   2790 O O   . PHE   A 1 350 ? 136.398 158.498 140.697 1.00 48.14  ? 376 PHE   A O   1 
ATOM   2791 C CB  . PHE   A 1 350 ? 133.310 158.566 141.598 1.00 38.27  ? 376 PHE   A CB  1 
ATOM   2792 C CG  . PHE   A 1 350 ? 133.895 159.932 141.793 1.00 36.28  ? 376 PHE   A CG  1 
ATOM   2793 C CD1 . PHE   A 1 350 ? 133.841 160.872 140.782 1.00 36.81  ? 376 PHE   A CD1 1 
ATOM   2794 C CD2 . PHE   A 1 350 ? 134.496 160.279 142.987 1.00 41.18  ? 376 PHE   A CD2 1 
ATOM   2795 C CE1 . PHE   A 1 350 ? 134.376 162.125 140.957 1.00 40.06  ? 376 PHE   A CE1 1 
ATOM   2796 C CE2 . PHE   A 1 350 ? 135.032 161.532 143.167 1.00 42.98  ? 376 PHE   A CE2 1 
ATOM   2797 C CZ  . PHE   A 1 350 ? 134.971 162.457 142.151 1.00 42.02  ? 376 PHE   A CZ  1 
ATOM   2798 N N   . LEU   A 1 351 ? 135.965 156.839 142.154 1.00 45.75  ? 377 LEU   A N   1 
ATOM   2799 C CA  . LEU   A 1 351 ? 137.249 157.004 142.836 1.00 42.18  ? 377 LEU   A CA  1 
ATOM   2800 C C   . LEU   A 1 351 ? 138.466 156.872 141.924 1.00 43.41  ? 377 LEU   A C   1 
ATOM   2801 O O   . LEU   A 1 351 ? 139.405 157.671 142.089 1.00 47.71  ? 377 LEU   A O   1 
ATOM   2802 C CB  . LEU   A 1 351 ? 137.359 156.019 144.007 1.00 42.59  ? 377 LEU   A CB  1 
ATOM   2803 C CG  . LEU   A 1 351 ? 137.941 156.606 145.297 1.00 42.70  ? 377 LEU   A CG  1 
ATOM   2804 C CD1 . LEU   A 1 351 ? 138.063 155.526 146.352 1.00 45.04  ? 377 LEU   A CD1 1 
ATOM   2805 C CD2 . LEU   A 1 351 ? 139.285 157.265 145.062 1.00 42.75  ? 377 LEU   A CD2 1 
ATOM   2806 N N   . PRO   A 1 352 ? 138.543 155.917 140.991 1.00 38.86  ? 378 PRO   A N   1 
ATOM   2807 C CA  . PRO   A 1 352 ? 139.720 155.867 140.109 1.00 39.78  ? 378 PRO   A CA  1 
ATOM   2808 C C   . PRO   A 1 352 ? 139.945 157.130 139.296 1.00 44.15  ? 378 PRO   A C   1 
ATOM   2809 O O   . PRO   A 1 352 ? 141.087 157.398 138.905 1.00 50.97  ? 378 PRO   A O   1 
ATOM   2810 C CB  . PRO   A 1 352 ? 139.419 154.667 139.202 1.00 43.27  ? 378 PRO   A CB  1 
ATOM   2811 C CG  . PRO   A 1 352 ? 138.556 153.805 140.006 1.00 43.53  ? 378 PRO   A CG  1 
ATOM   2812 C CD  . PRO   A 1 352 ? 137.710 154.714 140.840 1.00 43.35  ? 378 PRO   A CD  1 
ATOM   2813 N N   . TYR   A 1 353 ? 138.898 157.914 139.033 1.00 40.75  ? 379 TYR   A N   1 
ATOM   2814 C CA  . TYR   A 1 353 ? 138.997 159.147 138.260 1.00 38.19  ? 379 TYR   A CA  1 
ATOM   2815 C C   . TYR   A 1 353 ? 138.833 160.392 139.124 1.00 37.61  ? 379 TYR   A C   1 
ATOM   2816 O O   . TYR   A 1 353 ? 138.450 161.447 138.611 1.00 37.48  ? 379 TYR   A O   1 
ATOM   2817 C CB  . TYR   A 1 353 ? 137.956 159.152 137.144 1.00 38.26  ? 379 TYR   A CB  1 
ATOM   2818 C CG  . TYR   A 1 353 ? 138.019 157.951 136.239 1.00 37.97  ? 379 TYR   A CG  1 
ATOM   2819 C CD1 . TYR   A 1 353 ? 139.007 157.835 135.280 1.00 36.84  ? 379 TYR   A CD1 1 
ATOM   2820 C CD2 . TYR   A 1 353 ? 137.082 156.937 136.337 1.00 42.48  ? 379 TYR   A CD2 1 
ATOM   2821 C CE1 . TYR   A 1 353 ? 139.067 156.741 134.451 1.00 39.19  ? 379 TYR   A CE1 1 
ATOM   2822 C CE2 . TYR   A 1 353 ? 137.133 155.840 135.511 1.00 42.49  ? 379 TYR   A CE2 1 
ATOM   2823 C CZ  . TYR   A 1 353 ? 138.128 155.748 134.570 1.00 42.21  ? 379 TYR   A CZ  1 
ATOM   2824 O OH  . TYR   A 1 353 ? 138.187 154.657 133.738 1.00 46.17  ? 379 TYR   A OH  1 
ATOM   2825 N N   . SER   A 1 354 ? 139.125 160.297 140.422 1.00 37.12  ? 380 SER   A N   1 
ATOM   2826 C CA  . SER   A 1 354 ? 139.014 161.422 141.343 1.00 37.59  ? 380 SER   A CA  1 
ATOM   2827 C C   . SER   A 1 354 ? 140.327 162.170 141.508 1.00 42.37  ? 380 SER   A C   1 
ATOM   2828 O O   . SER   A 1 354 ? 140.569 162.759 142.568 1.00 45.93  ? 380 SER   A O   1 
ATOM   2829 C CB  . SER   A 1 354 ? 138.524 160.938 142.706 1.00 40.65  ? 380 SER   A CB  1 
ATOM   2830 O OG  . SER   A 1 354 ? 139.591 160.399 143.465 1.00 43.96  ? 380 SER   A OG  1 
ATOM   2831 N N   . HIS   A 1 355 ? 141.188 162.156 140.491 1.00 43.81  ? 381 HIS   A N   1 
ATOM   2832 C CA  . HIS   A 1 355 ? 142.535 162.695 140.603 1.00 43.29  ? 381 HIS   A CA  1 
ATOM   2833 C C   . HIS   A 1 355 ? 142.621 164.194 140.356 1.00 41.04  ? 381 HIS   A C   1 
ATOM   2834 O O   . HIS   A 1 355 ? 143.683 164.777 140.597 1.00 48.09  ? 381 HIS   A O   1 
ATOM   2835 C CB  . HIS   A 1 355 ? 143.466 161.976 139.629 1.00 45.12  ? 381 HIS   A CB  1 
ATOM   2836 C CG  . HIS   A 1 355 ? 143.618 160.515 139.909 1.00 48.55  ? 381 HIS   A CG  1 
ATOM   2837 N ND1 . HIS   A 1 355 ? 144.055 160.035 141.124 1.00 51.24  ? 381 HIS   A ND1 1 
ATOM   2838 C CD2 . HIS   A 1 355 ? 143.399 159.430 139.132 1.00 49.51  ? 381 HIS   A CD2 1 
ATOM   2839 C CE1 . HIS   A 1 355 ? 144.093 158.716 141.085 1.00 54.51  ? 381 HIS   A CE1 1 
ATOM   2840 N NE2 . HIS   A 1 355 ? 143.700 158.324 139.887 1.00 53.27  ? 381 HIS   A NE2 1 
ATOM   2841 N N   . PHE   A 1 356 ? 141.551 164.831 139.892 1.00 38.13  ? 382 PHE   A N   1 
ATOM   2842 C CA  . PHE   A 1 356 ? 141.553 166.271 139.684 1.00 39.07  ? 382 PHE   A CA  1 
ATOM   2843 C C   . PHE   A 1 356 ? 141.181 167.054 140.937 1.00 42.54  ? 382 PHE   A C   1 
ATOM   2844 O O   . PHE   A 1 356 ? 141.278 168.286 140.925 1.00 46.51  ? 382 PHE   A O   1 
ATOM   2845 C CB  . PHE   A 1 356 ? 140.604 166.647 138.538 1.00 42.10  ? 382 PHE   A CB  1 
ATOM   2846 C CG  . PHE   A 1 356 ? 139.145 166.435 138.842 1.00 41.38  ? 382 PHE   A CG  1 
ATOM   2847 C CD1 . PHE   A 1 356 ? 138.548 165.209 138.621 1.00 37.22  ? 382 PHE   A CD1 1 
ATOM   2848 C CD2 . PHE   A 1 356 ? 138.363 167.472 139.313 1.00 42.43  ? 382 PHE   A CD2 1 
ATOM   2849 C CE1 . PHE   A 1 356 ? 137.219 165.016 138.890 1.00 33.07  ? 382 PHE   A CE1 1 
ATOM   2850 C CE2 . PHE   A 1 356 ? 137.032 167.280 139.580 1.00 40.75  ? 382 PHE   A CE2 1 
ATOM   2851 C CZ  . PHE   A 1 356 ? 136.460 166.050 139.366 1.00 34.69  ? 382 PHE   A CZ  1 
ATOM   2852 N N   . LEU   A 1 357 ? 140.764 166.381 142.009 1.00 41.54  ? 383 LEU   A N   1 
ATOM   2853 C CA  . LEU   A 1 357 ? 140.469 167.020 143.284 1.00 42.94  ? 383 LEU   A CA  1 
ATOM   2854 C C   . LEU   A 1 357 ? 141.662 166.987 144.229 1.00 46.44  ? 383 LEU   A C   1 
ATOM   2855 O O   . LEU   A 1 357 ? 142.000 168.006 144.837 1.00 49.90  ? 383 LEU   A O   1 
ATOM   2856 C CB  . LEU   A 1 357 ? 139.267 166.339 143.949 1.00 42.07  ? 383 LEU   A CB  1 
ATOM   2857 C CG  . LEU   A 1 357 ? 137.936 166.378 143.197 1.00 43.27  ? 383 LEU   A CG  1 
ATOM   2858 C CD1 . LEU   A 1 357 ? 136.899 165.560 143.940 1.00 42.85  ? 383 LEU   A CD1 1 
ATOM   2859 C CD2 . LEU   A 1 357 ? 137.449 167.806 143.003 1.00 44.16  ? 383 LEU   A CD2 1 
ATOM   2860 N N   . THR   A 1 358 ? 142.308 165.829 144.360 1.00 46.92  ? 384 THR   A N   1 
ATOM   2861 C CA  . THR   A 1 358 ? 143.490 165.672 145.203 1.00 48.09  ? 384 THR   A CA  1 
ATOM   2862 C C   . THR   A 1 358 ? 144.718 165.809 144.308 1.00 47.39  ? 384 THR   A C   1 
ATOM   2863 O O   . THR   A 1 358 ? 145.376 164.835 143.947 1.00 51.27  ? 384 THR   A O   1 
ATOM   2864 C CB  . THR   A 1 358 ? 143.461 164.330 145.926 1.00 48.63  ? 384 THR   A CB  1 
ATOM   2865 O OG1 . THR   A 1 358 ? 143.424 163.267 144.968 1.00 46.09  ? 384 THR   A OG1 1 
ATOM   2866 C CG2 . THR   A 1 358 ? 142.240 164.236 146.826 1.00 47.62  ? 384 THR   A CG2 1 
ATOM   2867 N N   . GLN   A 1 359 ? 145.023 167.053 143.944 1.00 45.46  ? 385 GLN   A N   1 
ATOM   2868 C CA  . GLN   A 1 359 ? 146.080 167.328 142.980 1.00 45.38  ? 385 GLN   A CA  1 
ATOM   2869 C C   . GLN   A 1 359 ? 147.475 167.318 143.584 1.00 48.49  ? 385 GLN   A C   1 
ATOM   2870 O O   . GLN   A 1 359 ? 148.453 167.310 142.829 1.00 52.03  ? 385 GLN   A O   1 
ATOM   2871 C CB  . GLN   A 1 359 ? 145.842 168.677 142.304 1.00 50.09  ? 385 GLN   A CB  1 
ATOM   2872 C CG  . GLN   A 1 359 ? 144.822 168.636 141.190 1.00 49.38  ? 385 GLN   A CG  1 
ATOM   2873 C CD  . GLN   A 1 359 ? 144.699 169.960 140.478 1.00 54.91  ? 385 GLN   A CD  1 
ATOM   2874 O OE1 . GLN   A 1 359 ? 145.304 170.951 140.881 1.00 58.84  ? 385 GLN   A OE1 1 
ATOM   2875 N NE2 . GLN   A 1 359 ? 143.913 169.987 139.411 1.00 56.22  ? 385 GLN   A NE2 1 
ATOM   2876 N N   . GLY   A 1 360 ? 147.600 167.332 144.908 1.00 48.94  ? 386 GLY   A N   1 
ATOM   2877 C CA  . GLY   A 1 360 ? 148.919 167.307 145.512 1.00 47.53  ? 386 GLY   A CA  1 
ATOM   2878 C C   . GLY   A 1 360 ? 149.674 166.030 145.203 1.00 49.85  ? 386 GLY   A C   1 
ATOM   2879 O O   . GLY   A 1 360 ? 150.895 166.042 145.041 1.00 53.69  ? 386 GLY   A O   1 
ATOM   2880 N N   . TYR   A 1 361 ? 148.958 164.913 145.117 1.00 51.12  ? 387 TYR   A N   1 
ATOM   2881 C CA  . TYR   A 1 361 ? 149.583 163.620 144.886 1.00 50.87  ? 387 TYR   A CA  1 
ATOM   2882 C C   . TYR   A 1 361 ? 149.881 163.353 143.418 1.00 55.66  ? 387 TYR   A C   1 
ATOM   2883 O O   . TYR   A 1 361 ? 150.506 162.333 143.111 1.00 58.88  ? 387 TYR   A O   1 
ATOM   2884 C CB  . TYR   A 1 361 ? 148.685 162.509 145.433 1.00 49.08  ? 387 TYR   A CB  1 
ATOM   2885 C CG  . TYR   A 1 361 ? 148.391 162.644 146.909 1.00 49.73  ? 387 TYR   A CG  1 
ATOM   2886 C CD1 . TYR   A 1 361 ? 147.300 163.369 147.355 1.00 48.04  ? 387 TYR   A CD1 1 
ATOM   2887 C CD2 . TYR   A 1 361 ? 149.208 162.050 147.854 1.00 51.04  ? 387 TYR   A CD2 1 
ATOM   2888 C CE1 . TYR   A 1 361 ? 147.034 163.498 148.698 1.00 48.14  ? 387 TYR   A CE1 1 
ATOM   2889 C CE2 . TYR   A 1 361 ? 148.949 162.176 149.197 1.00 47.44  ? 387 TYR   A CE2 1 
ATOM   2890 C CZ  . TYR   A 1 361 ? 147.862 162.901 149.614 1.00 48.67  ? 387 TYR   A CZ  1 
ATOM   2891 O OH  . TYR   A 1 361 ? 147.600 163.024 150.956 1.00 56.72  ? 387 TYR   A OH  1 
ATOM   2892 N N   . ASN   A 1 362 ? 149.463 164.230 142.509 1.00 58.61  ? 388 ASN   A N   1 
ATOM   2893 C CA  . ASN   A 1 362 ? 149.753 164.023 141.099 1.00 59.26  ? 388 ASN   A CA  1 
ATOM   2894 C C   . ASN   A 1 362 ? 151.240 164.193 140.818 1.00 58.99  ? 388 ASN   A C   1 
ATOM   2895 O O   . ASN   A 1 362 ? 151.945 164.964 141.474 1.00 60.12  ? 388 ASN   A O   1 
ATOM   2896 C CB  . ASN   A 1 362 ? 148.959 164.996 140.223 1.00 58.04  ? 388 ASN   A CB  1 
ATOM   2897 C CG  . ASN   A 1 362 ? 147.491 164.625 140.093 1.00 55.56  ? 388 ASN   A CG  1 
ATOM   2898 O OD1 . ASN   A 1 362 ? 146.620 165.467 140.276 1.00 54.69  ? 388 ASN   A OD1 1 
ATOM   2899 N ND2 . ASN   A 1 362 ? 147.212 163.376 139.750 1.00 56.20  ? 388 ASN   A ND2 1 
ATOM   2900 N N   . ASN   A 1 363 ? 151.703 163.457 139.817 1.00 56.32  ? 389 ASN   A N   1 
ATOM   2901 C CA  . ASN   A 1 363 ? 153.082 163.455 139.352 1.00 52.83  ? 389 ASN   A CA  1 
ATOM   2902 C C   . ASN   A 1 363 ? 153.024 163.171 137.854 1.00 50.50  ? 389 ASN   A C   1 
ATOM   2903 O O   . ASN   A 1 363 ? 152.015 163.459 137.201 1.00 51.22  ? 389 ASN   A O   1 
ATOM   2904 C CB  . ASN   A 1 363 ? 153.926 162.440 140.145 1.00 54.79  ? 389 ASN   A CB  1 
ATOM   2905 C CG  . ASN   A 1 363 ? 154.034 162.790 141.611 1.00 57.64  ? 389 ASN   A CG  1 
ATOM   2906 O OD1 . ASN   A 1 363 ? 153.599 162.032 142.475 1.00 58.69  ? 389 ASN   A OD1 1 
ATOM   2907 N ND2 . ASN   A 1 363 ? 154.610 163.949 141.900 1.00 57.29  ? 389 ASN   A ND2 1 
ATOM   2908 N N   . TRP   A 1 364 ? 154.126 162.679 137.290 1.00 48.21  ? 390 TRP   A N   1 
ATOM   2909 C CA  . TRP   A 1 364 ? 154.086 162.146 135.933 1.00 47.44  ? 390 TRP   A CA  1 
ATOM   2910 C C   . TRP   A 1 364 ? 152.958 161.129 135.776 1.00 51.59  ? 390 TRP   A C   1 
ATOM   2911 O O   . TRP   A 1 364 ? 152.236 161.136 134.774 1.00 57.07  ? 390 TRP   A O   1 
ATOM   2912 C CB  . TRP   A 1 364 ? 155.436 161.519 135.582 1.00 46.36  ? 390 TRP   A CB  1 
ATOM   2913 C CG  . TRP   A 1 364 ? 156.580 162.497 135.547 1.00 43.62  ? 390 TRP   A CG  1 
ATOM   2914 C CD1 . TRP   A 1 364 ? 156.504 163.857 135.604 1.00 41.72  ? 390 TRP   A CD1 1 
ATOM   2915 C CD2 . TRP   A 1 364 ? 157.970 162.180 135.454 1.00 39.22  ? 390 TRP   A CD2 1 
ATOM   2916 N NE1 . TRP   A 1 364 ? 157.757 164.403 135.549 1.00 44.82  ? 390 TRP   A NE1 1 
ATOM   2917 C CE2 . TRP   A 1 364 ? 158.676 163.393 135.456 1.00 41.95  ? 390 TRP   A CE2 1 
ATOM   2918 C CE3 . TRP   A 1 364 ? 158.686 160.987 135.369 1.00 38.01  ? 390 TRP   A CE3 1 
ATOM   2919 C CZ2 . TRP   A 1 364 ? 160.060 163.446 135.375 1.00 44.01  ? 390 TRP   A CZ2 1 
ATOM   2920 C CZ3 . TRP   A 1 364 ? 160.054 161.041 135.287 1.00 39.30  ? 390 TRP   A CZ3 1 
ATOM   2921 C CH2 . TRP   A 1 364 ? 160.730 162.261 135.292 1.00 43.21  ? 390 TRP   A CH2 1 
ATOM   2922 N N   . THR   A 1 365 ? 152.790 160.250 136.762 1.00 51.28  ? 391 THR   A N   1 
ATOM   2923 C CA  . THR   A 1 365 ? 151.613 159.401 136.847 1.00 53.09  ? 391 THR   A CA  1 
ATOM   2924 C C   . THR   A 1 365 ? 150.496 160.168 137.549 1.00 57.93  ? 391 THR   A C   1 
ATOM   2925 O O   . THR   A 1 365 ? 150.660 161.324 137.942 1.00 63.11  ? 391 THR   A O   1 
ATOM   2926 C CB  . THR   A 1 365 ? 151.933 158.100 137.582 1.00 57.09  ? 391 THR   A CB  1 
ATOM   2927 O OG1 . THR   A 1 365 ? 150.886 157.150 137.349 1.00 56.05  ? 391 THR   A OG1 1 
ATOM   2928 C CG2 . THR   A 1 365 ? 152.065 158.335 139.090 1.00 59.12  ? 391 THR   A CG2 1 
ATOM   2929 N N   . ASN   A 1 366 ? 149.348 159.517 137.727 1.00 54.47  ? 392 ASN   A N   1 
ATOM   2930 C CA  . ASN   A 1 366 ? 148.185 160.121 138.368 1.00 56.92  ? 392 ASN   A CA  1 
ATOM   2931 C C   . ASN   A 1 366 ? 147.949 159.463 139.721 1.00 58.16  ? 392 ASN   A C   1 
ATOM   2932 O O   . ASN   A 1 366 ? 147.773 158.243 139.802 1.00 61.33  ? 392 ASN   A O   1 
ATOM   2933 C CB  . ASN   A 1 366 ? 146.943 159.991 137.486 1.00 59.63  ? 392 ASN   A CB  1 
ATOM   2934 C CG  . ASN   A 1 366 ? 146.762 161.174 136.551 1.00 61.62  ? 392 ASN   A CG  1 
ATOM   2935 O OD1 . ASN   A 1 366 ? 146.967 162.324 136.935 1.00 56.20  ? 392 ASN   A OD1 1 
ATOM   2936 N ND2 . ASN   A 1 366 ? 146.370 160.893 135.314 1.00 68.11  ? 392 ASN   A ND2 1 
ATOM   2937 N N   . GLY   A 1 367 ? 147.948 160.275 140.774 1.00 57.73  ? 393 GLY   A N   1 
ATOM   2938 C CA  . GLY   A 1 367 ? 147.585 159.829 142.105 1.00 61.04  ? 393 GLY   A CA  1 
ATOM   2939 C C   . GLY   A 1 367 ? 148.514 158.799 142.709 1.00 59.85  ? 393 GLY   A C   1 
ATOM   2940 O O   . GLY   A 1 367 ? 149.418 158.289 142.042 1.00 57.68  ? 393 GLY   A O   1 
ATOM   2941 N N   . LEU   A 1 368 ? 148.296 158.490 143.984 1.00 59.77  ? 394 LEU   A N   1 
ATOM   2942 C CA  . LEU   A 1 368 ? 149.042 157.428 144.638 1.00 57.71  ? 394 LEU   A CA  1 
ATOM   2943 C C   . LEU   A 1 368 ? 148.673 156.079 144.039 1.00 58.50  ? 394 LEU   A C   1 
ATOM   2944 O O   . LEU   A 1 368 ? 147.547 155.860 143.584 1.00 59.45  ? 394 LEU   A O   1 
ATOM   2945 C CB  . LEU   A 1 368 ? 148.759 157.413 146.140 1.00 55.69  ? 394 LEU   A CB  1 
ATOM   2946 C CG  . LEU   A 1 368 ? 149.333 158.553 146.979 1.00 56.71  ? 394 LEU   A CG  1 
ATOM   2947 C CD1 . LEU   A 1 368 ? 148.758 158.503 148.381 1.00 54.81  ? 394 LEU   A CD1 1 
ATOM   2948 C CD2 . LEU   A 1 368 ? 150.848 158.488 147.023 1.00 54.36  ? 394 LEU   A CD2 1 
ATOM   2949 N N   . TYR   A 1 369 ? 149.638 155.169 144.042 1.00 50.19  ? 395 TYR   A N   1 
ATOM   2950 C CA  . TYR   A 1 369 ? 149.402 153.835 143.517 1.00 46.84  ? 395 TYR   A CA  1 
ATOM   2951 C C   . TYR   A 1 369 ? 148.563 153.026 144.496 1.00 52.48  ? 395 TYR   A C   1 
ATOM   2952 O O   . TYR   A 1 369 ? 148.764 153.096 145.712 1.00 54.89  ? 395 TYR   A O   1 
ATOM   2953 C CB  . TYR   A 1 369 ? 150.731 153.132 143.258 1.00 45.38  ? 395 TYR   A CB  1 
ATOM   2954 C CG  . TYR   A 1 369 ? 150.607 151.840 142.494 1.00 46.86  ? 395 TYR   A CG  1 
ATOM   2955 C CD1 . TYR   A 1 369 ? 150.617 151.828 141.110 1.00 51.43  ? 395 TYR   A CD1 1 
ATOM   2956 C CD2 . TYR   A 1 369 ? 150.489 150.631 143.153 1.00 47.50  ? 395 TYR   A CD2 1 
ATOM   2957 C CE1 . TYR   A 1 369 ? 150.508 150.654 140.408 1.00 52.34  ? 395 TYR   A CE1 1 
ATOM   2958 C CE2 . TYR   A 1 369 ? 150.376 149.452 142.457 1.00 49.11  ? 395 TYR   A CE2 1 
ATOM   2959 C CZ  . TYR   A 1 369 ? 150.388 149.469 141.084 1.00 51.52  ? 395 TYR   A CZ  1 
ATOM   2960 O OH  . TYR   A 1 369 ? 150.277 148.295 140.381 1.00 58.12  ? 395 TYR   A OH  1 
ATOM   2961 N N   . GLY   A 1 370 ? 147.611 152.262 143.958 1.00 51.80  ? 396 GLY   A N   1 
ATOM   2962 C CA  . GLY   A 1 370 ? 146.853 151.305 144.743 1.00 46.49  ? 396 GLY   A CA  1 
ATOM   2963 C C   . GLY   A 1 370 ? 145.366 151.238 144.460 1.00 51.93  ? 396 GLY   A C   1 
ATOM   2964 O O   . GLY   A 1 370 ? 144.768 150.169 144.613 1.00 56.15  ? 396 GLY   A O   1 
ATOM   2965 N N   . TYR   A 1 371 ? 144.754 152.353 144.047 1.00 53.70  ? 397 TYR   A N   1 
ATOM   2966 C CA  . TYR   A 1 371 ? 143.307 152.436 143.872 1.00 48.62  ? 397 TYR   A CA  1 
ATOM   2967 C C   . TYR   A 1 371 ? 142.925 152.952 142.490 1.00 47.19  ? 397 TYR   A C   1 
ATOM   2968 O O   . TYR   A 1 371 ? 141.869 153.568 142.330 1.00 51.87  ? 397 TYR   A O   1 
ATOM   2969 C CB  . TYR   A 1 371 ? 142.680 153.309 144.959 1.00 50.53  ? 397 TYR   A CB  1 
ATOM   2970 C CG  . TYR   A 1 371 ? 143.185 154.735 145.005 1.00 52.59  ? 397 TYR   A CG  1 
ATOM   2971 C CD1 . TYR   A 1 371 ? 144.293 155.074 145.763 1.00 49.71  ? 397 TYR   A CD1 1 
ATOM   2972 C CD2 . TYR   A 1 371 ? 142.538 155.745 144.308 1.00 52.79  ? 397 TYR   A CD2 1 
ATOM   2973 C CE1 . TYR   A 1 371 ? 144.750 156.374 145.814 1.00 52.57  ? 397 TYR   A CE1 1 
ATOM   2974 C CE2 . TYR   A 1 371 ? 142.989 157.046 144.353 1.00 52.96  ? 397 TYR   A CE2 1 
ATOM   2975 C CZ  . TYR   A 1 371 ? 144.093 157.355 145.108 1.00 55.51  ? 397 TYR   A CZ  1 
ATOM   2976 O OH  . TYR   A 1 371 ? 144.544 158.652 145.155 1.00 56.69  ? 397 TYR   A OH  1 
ATOM   2977 N N   . SER   A 1 372 ? 143.761 152.694 141.481 1.00 50.27  ? 398 SER   A N   1 
ATOM   2978 C CA  . SER   A 1 372 ? 143.501 153.112 140.109 1.00 55.54  ? 398 SER   A CA  1 
ATOM   2979 C C   . SER   A 1 372 ? 143.349 151.959 139.128 1.00 52.42  ? 398 SER   A C   1 
ATOM   2980 O O   . SER   A 1 372 ? 142.930 152.196 137.991 1.00 51.88  ? 398 SER   A O   1 
ATOM   2981 C CB  . SER   A 1 372 ? 144.626 154.032 139.614 1.00 58.58  ? 398 SER   A CB  1 
ATOM   2982 O OG  . SER   A 1 372 ? 144.723 155.194 140.418 1.00 63.51  ? 398 SER   A OG  1 
ATOM   2983 N N   . TRP   A 1 373 ? 143.680 150.731 139.521 1.00 50.02  ? 399 TRP   A N   1 
ATOM   2984 C CA  . TRP   A 1 373 ? 143.587 149.550 138.669 1.00 52.77  ? 399 TRP   A CA  1 
ATOM   2985 C C   . TRP   A 1 373 ? 144.496 149.629 137.445 1.00 58.94  ? 399 TRP   A C   1 
ATOM   2986 O O   . TRP   A 1 373 ? 144.245 148.946 136.448 1.00 60.51  ? 399 TRP   A O   1 
ATOM   2987 C CB  . TRP   A 1 373 ? 142.140 149.296 138.228 1.00 48.42  ? 399 TRP   A CB  1 
ATOM   2988 C CG  . TRP   A 1 373 ? 141.154 149.289 139.357 1.00 45.72  ? 399 TRP   A CG  1 
ATOM   2989 C CD1 . TRP   A 1 373 ? 140.070 150.100 139.503 1.00 50.58  ? 399 TRP   A CD1 1 
ATOM   2990 C CD2 . TRP   A 1 373 ? 141.165 148.427 140.500 1.00 46.45  ? 399 TRP   A CD2 1 
ATOM   2991 N NE1 . TRP   A 1 373 ? 139.405 149.797 140.664 1.00 50.84  ? 399 TRP   A NE1 1 
ATOM   2992 C CE2 . TRP   A 1 373 ? 140.059 148.773 141.294 1.00 45.26  ? 399 TRP   A CE2 1 
ATOM   2993 C CE3 . TRP   A 1 373 ? 142.005 147.398 140.928 1.00 50.63  ? 399 TRP   A CE3 1 
ATOM   2994 C CZ2 . TRP   A 1 373 ? 139.772 148.129 142.491 1.00 44.99  ? 399 TRP   A CZ2 1 
ATOM   2995 C CZ3 . TRP   A 1 373 ? 141.717 146.759 142.114 1.00 49.39  ? 399 TRP   A CZ3 1 
ATOM   2996 C CH2 . TRP   A 1 373 ? 140.611 147.126 142.882 1.00 46.60  ? 399 TRP   A CH2 1 
ATOM   2997 N N   . ASP   A 1 374 ? 145.557 150.439 137.503 1.00 56.17  ? 400 ASP   A N   1 
ATOM   2998 C CA  . ASP   A 1 374 ? 146.517 150.568 136.402 1.00 51.27  ? 400 ASP   A CA  1 
ATOM   2999 C C   . ASP   A 1 374 ? 147.688 149.630 136.677 1.00 52.79  ? 400 ASP   A C   1 
ATOM   3000 O O   . ASP   A 1 374 ? 148.789 150.036 137.052 1.00 55.81  ? 400 ASP   A O   1 
ATOM   3001 C CB  . ASP   A 1 374 ? 146.966 152.017 136.236 1.00 55.31  ? 400 ASP   A CB  1 
ATOM   3002 C CG  . ASP   A 1 374 ? 147.519 152.621 137.518 1.00 66.55  ? 400 ASP   A CG  1 
ATOM   3003 O OD1 . ASP   A 1 374 ? 147.464 151.947 138.568 1.00 66.78  ? 400 ASP   A OD1 1 
ATOM   3004 O OD2 . ASP   A 1 374 ? 148.008 153.769 137.473 1.00 66.86  ? 400 ASP   A OD2 1 
ATOM   3005 N N   . MET   A 1 375 ? 147.438 148.342 136.471 1.00 53.98  ? 401 MET   A N   1 
ATOM   3006 C CA  . MET   A 1 375 ? 148.384 147.300 136.842 1.00 54.88  ? 401 MET   A CA  1 
ATOM   3007 C C   . MET   A 1 375 ? 149.342 147.024 135.694 1.00 58.20  ? 401 MET   A C   1 
ATOM   3008 O O   . MET   A 1 375 ? 148.910 146.755 134.568 1.00 61.12  ? 401 MET   A O   1 
ATOM   3009 C CB  . MET   A 1 375 ? 147.649 146.013 137.216 1.00 57.44  ? 401 MET   A CB  1 
ATOM   3010 C CG  . MET   A 1 375 ? 146.469 146.205 138.143 1.00 54.10  ? 401 MET   A CG  1 
ATOM   3011 S SD  . MET   A 1 375 ? 145.764 144.636 138.663 1.00 68.20  ? 401 MET   A SD  1 
ATOM   3012 C CE  . MET   A 1 375 ? 144.334 145.202 139.570 1.00 57.33  ? 401 MET   A CE  1 
ATOM   3013 N N   . MET   A 1 376 ? 150.640 147.082 135.987 1.00 56.37  ? 402 MET   A N   1 
ATOM   3014 C CA  . MET   A 1 376 ? 151.681 146.677 135.044 1.00 58.24  ? 402 MET   A CA  1 
ATOM   3015 C C   . MET   A 1 376 ? 151.644 147.527 133.775 1.00 57.41  ? 402 MET   A C   1 
ATOM   3016 O O   . MET   A 1 376 ? 151.727 147.012 132.659 1.00 61.93  ? 402 MET   A O   1 
ATOM   3017 C CB  . MET   A 1 376 ? 151.550 145.193 134.692 1.00 58.37  ? 402 MET   A CB  1 
ATOM   3018 C CG  . MET   A 1 376 ? 151.334 144.244 135.863 1.00 63.07  ? 402 MET   A CG  1 
ATOM   3019 S SD  . MET   A 1 376 ? 152.731 144.154 136.988 1.00 79.19  ? 402 MET   A SD  1 
ATOM   3020 C CE  . MET   A 1 376 ? 152.200 142.823 138.061 1.00 67.70  ? 402 MET   A CE  1 
ATOM   3021 N N   . VAL   A 1 377 ? 151.532 148.843 133.953 1.00 51.09  ? 403 VAL   A N   1 
ATOM   3022 C CA  . VAL   A 1 377 ? 151.411 149.772 132.833 1.00 50.48  ? 403 VAL   A CA  1 
ATOM   3023 C C   . VAL   A 1 377 ? 152.622 150.695 132.767 1.00 53.21  ? 403 VAL   A C   1 
ATOM   3024 O O   . VAL   A 1 377 ? 153.002 151.146 131.680 1.00 56.17  ? 403 VAL   A O   1 
ATOM   3025 C CB  . VAL   A 1 377 ? 150.109 150.588 132.939 1.00 50.03  ? 403 VAL   A CB  1 
ATOM   3026 C CG1 . VAL   A 1 377 ? 149.878 151.403 131.673 1.00 50.78  ? 403 VAL   A CG1 1 
ATOM   3027 C CG2 . VAL   A 1 377 ? 148.929 149.667 133.214 1.00 53.65  ? 403 VAL   A CG2 1 
ATOM   3028 N N   . HIS   A 1 378 ? 153.242 150.974 133.914 1.00 53.02  ? 404 HIS   A N   1 
ATOM   3029 C CA  . HIS   A 1 378 ? 154.376 151.888 134.007 1.00 48.39  ? 404 HIS   A CA  1 
ATOM   3030 C C   . HIS   A 1 378 ? 155.551 151.184 134.668 1.00 48.95  ? 404 HIS   A C   1 
ATOM   3031 O O   . HIS   A 1 378 ? 155.393 150.566 135.726 1.00 54.25  ? 404 HIS   A O   1 
ATOM   3032 C CB  . HIS   A 1 378 ? 154.012 153.139 134.804 1.00 47.50  ? 404 HIS   A CB  1 
ATOM   3033 C CG  . HIS   A 1 378 ? 152.965 153.988 134.156 1.00 49.27  ? 404 HIS   A CG  1 
ATOM   3034 N ND1 . HIS   A 1 378 ? 153.099 154.491 132.881 1.00 53.04  ? 404 HIS   A ND1 1 
ATOM   3035 C CD2 . HIS   A 1 378 ? 151.773 154.436 134.615 1.00 46.26  ? 404 HIS   A CD2 1 
ATOM   3036 C CE1 . HIS   A 1 378 ? 152.031 155.206 132.578 1.00 50.58  ? 404 HIS   A CE1 1 
ATOM   3037 N NE2 . HIS   A 1 378 ? 151.211 155.189 133.613 1.00 44.85  ? 404 HIS   A NE2 1 
ATOM   3038 N N   . SER   A 1 379 ? 156.721 151.282 134.042 1.00 43.89  ? 405 SER   A N   1 
ATOM   3039 C CA  . SER   A 1 379 ? 157.965 150.745 134.572 1.00 44.92  ? 405 SER   A CA  1 
ATOM   3040 C C   . SER   A 1 379 ? 159.001 151.854 134.576 1.00 43.73  ? 405 SER   A C   1 
ATOM   3041 O O   . SER   A 1 379 ? 159.109 152.608 133.606 1.00 48.35  ? 405 SER   A O   1 
ATOM   3042 C CB  . SER   A 1 379 ? 158.466 149.561 133.740 1.00 48.49  ? 405 SER   A CB  1 
ATOM   3043 O OG  . SER   A 1 379 ? 157.519 148.508 133.731 1.00 49.32  ? 405 SER   A OG  1 
ATOM   3044 N N   . ARG   A 1 380 ? 159.767 151.943 135.662 1.00 40.31  ? 406 ARG   A N   1 
ATOM   3045 C CA  . ARG   A 1 380 ? 160.692 153.045 135.887 1.00 41.70  ? 406 ARG   A CA  1 
ATOM   3046 C C   . ARG   A 1 380 ? 162.086 152.511 136.164 1.00 40.44  ? 406 ARG   A C   1 
ATOM   3047 O O   . ARG   A 1 380 ? 162.245 151.482 136.826 1.00 44.28  ? 406 ARG   A O   1 
ATOM   3048 C CB  . ARG   A 1 380 ? 160.236 153.917 137.053 1.00 40.58  ? 406 ARG   A CB  1 
ATOM   3049 C CG  . ARG   A 1 380 ? 158.741 154.072 137.131 1.00 43.92  ? 406 ARG   A CG  1 
ATOM   3050 C CD  . ARG   A 1 380 ? 158.340 155.263 137.963 1.00 44.72  ? 406 ARG   A CD  1 
ATOM   3051 N NE  . ARG   A 1 380 ? 156.892 155.338 138.101 1.00 48.36  ? 406 ARG   A NE  1 
ATOM   3052 C CZ  . ARG   A 1 380 ? 156.219 156.415 138.482 1.00 53.25  ? 406 ARG   A CZ  1 
ATOM   3053 N NH1 . ARG   A 1 380 ? 156.829 157.552 138.780 1.00 55.45  ? 406 ARG   A NH1 1 
ATOM   3054 N NH2 . ARG   A 1 380 ? 154.895 156.352 138.568 1.00 52.97  ? 406 ARG   A NH2 1 
ATOM   3055 N N   . SER   A 1 381 ? 163.092 153.222 135.655 1.00 35.31  ? 407 SER   A N   1 
ATOM   3056 C CA  . SER   A 1 381 ? 164.495 152.874 135.868 1.00 32.30  ? 407 SER   A CA  1 
ATOM   3057 C C   . SER   A 1 381 ? 165.227 154.108 136.370 1.00 34.43  ? 407 SER   A C   1 
ATOM   3058 O O   . SER   A 1 381 ? 165.378 155.087 135.632 1.00 37.53  ? 407 SER   A O   1 
ATOM   3059 C CB  . SER   A 1 381 ? 165.135 152.347 134.586 1.00 37.78  ? 407 SER   A CB  1 
ATOM   3060 O OG  . SER   A 1 381 ? 166.483 151.975 134.806 1.00 43.92  ? 407 SER   A OG  1 
ATOM   3061 N N   . HIS   A 1 382 ? 165.682 154.060 137.618 1.00 34.40  ? 408 HIS   A N   1 
ATOM   3062 C CA  . HIS   A 1 382 ? 166.363 155.184 138.246 1.00 33.95  ? 408 HIS   A CA  1 
ATOM   3063 C C   . HIS   A 1 382 ? 167.863 155.075 138.020 1.00 32.98  ? 408 HIS   A C   1 
ATOM   3064 O O   . HIS   A 1 382 ? 168.443 153.997 138.186 1.00 35.42  ? 408 HIS   A O   1 
ATOM   3065 C CB  . HIS   A 1 382 ? 166.059 155.229 139.741 1.00 34.56  ? 408 HIS   A CB  1 
ATOM   3066 C CG  . HIS   A 1 382 ? 164.612 155.431 140.057 1.00 37.04  ? 408 HIS   A CG  1 
ATOM   3067 N ND1 . HIS   A 1 382 ? 163.667 154.444 139.884 1.00 36.19  ? 408 HIS   A ND1 1 
ATOM   3068 C CD2 . HIS   A 1 382 ? 163.947 156.506 140.540 1.00 41.69  ? 408 HIS   A CD2 1 
ATOM   3069 C CE1 . HIS   A 1 382 ? 162.483 154.902 140.246 1.00 40.91  ? 408 HIS   A CE1 1 
ATOM   3070 N NE2 . HIS   A 1 382 ? 162.625 156.151 140.647 1.00 43.99  ? 408 HIS   A NE2 1 
ATOM   3071 N N   . GLN   A 1 383 ? 168.484 156.194 137.649 1.00 32.30  ? 409 GLN   A N   1 
ATOM   3072 C CA  . GLN   A 1 383 ? 169.900 156.225 137.305 1.00 29.83  ? 409 GLN   A CA  1 
ATOM   3073 C C   . GLN   A 1 383 ? 170.772 156.860 138.376 1.00 30.76  ? 409 GLN   A C   1 
ATOM   3074 O O   . GLN   A 1 383 ? 171.920 156.440 138.545 1.00 35.39  ? 409 GLN   A O   1 
ATOM   3075 C CB  . GLN   A 1 383 ? 170.104 156.977 135.983 1.00 33.86  ? 409 GLN   A CB  1 
ATOM   3076 C CG  . GLN   A 1 383 ? 171.550 157.083 135.495 1.00 33.80  ? 409 GLN   A CG  1 
ATOM   3077 C CD  . GLN   A 1 383 ? 172.230 155.739 135.355 1.00 36.57  ? 409 GLN   A CD  1 
ATOM   3078 O OE1 . GLN   A 1 383 ? 171.575 154.716 135.165 1.00 38.76  ? 409 GLN   A OE1 1 
ATOM   3079 N NE2 . GLN   A 1 383 ? 173.553 155.732 135.451 1.00 37.79  ? 409 GLN   A NE2 1 
ATOM   3080 N N   . HIS   A 1 384 ? 170.269 157.856 139.098 1.00 33.21  ? 410 HIS   A N   1 
ATOM   3081 C CA  . HIS   A 1 384 ? 171.095 158.572 140.058 1.00 33.98  ? 410 HIS   A CA  1 
ATOM   3082 C C   . HIS   A 1 384 ? 170.203 159.272 141.070 1.00 35.83  ? 410 HIS   A C   1 
ATOM   3083 O O   . HIS   A 1 384 ? 169.128 159.764 140.721 1.00 38.97  ? 410 HIS   A O   1 
ATOM   3084 C CB  . HIS   A 1 384 ? 171.996 159.585 139.345 1.00 32.68  ? 410 HIS   A CB  1 
ATOM   3085 C CG  . HIS   A 1 384 ? 173.045 160.189 140.222 1.00 35.79  ? 410 HIS   A CG  1 
ATOM   3086 N ND1 . HIS   A 1 384 ? 173.434 161.506 140.113 1.00 39.94  ? 410 HIS   A ND1 1 
ATOM   3087 C CD2 . HIS   A 1 384 ? 173.800 159.655 141.210 1.00 36.73  ? 410 HIS   A CD2 1 
ATOM   3088 C CE1 . HIS   A 1 384 ? 174.376 161.760 141.003 1.00 41.88  ? 410 HIS   A CE1 1 
ATOM   3089 N NE2 . HIS   A 1 384 ? 174.615 160.653 141.683 1.00 40.19  ? 410 HIS   A NE2 1 
ATOM   3090 N N   . VAL   A 1 385 ? 170.656 159.308 142.323 1.00 37.02  ? 411 VAL   A N   1 
ATOM   3091 C CA  . VAL   A 1 385 ? 169.954 159.983 143.410 1.00 37.47  ? 411 VAL   A CA  1 
ATOM   3092 C C   . VAL   A 1 385 ? 170.998 160.631 144.306 1.00 39.54  ? 411 VAL   A C   1 
ATOM   3093 O O   . VAL   A 1 385 ? 171.833 159.931 144.890 1.00 43.30  ? 411 VAL   A O   1 
ATOM   3094 C CB  . VAL   A 1 385 ? 169.074 159.024 144.229 1.00 40.60  ? 411 VAL   A CB  1 
ATOM   3095 C CG1 . VAL   A 1 385 ? 168.376 159.777 145.355 1.00 43.34  ? 411 VAL   A CG1 1 
ATOM   3096 C CG2 . VAL   A 1 385 ? 168.060 158.323 143.335 1.00 40.20  ? 411 VAL   A CG2 1 
ATOM   3097 N N   . LYS   A 1 386 ? 170.961 161.958 144.410 1.00 38.12  ? 412 LYS   A N   1 
ATOM   3098 C CA  . LYS   A 1 386 ? 171.886 162.726 145.234 1.00 39.91  ? 412 LYS   A CA  1 
ATOM   3099 C C   . LYS   A 1 386 ? 171.097 163.566 146.226 1.00 41.94  ? 412 LYS   A C   1 
ATOM   3100 O O   . LYS   A 1 386 ? 170.156 164.266 145.840 1.00 45.05  ? 412 LYS   A O   1 
ATOM   3101 C CB  . LYS   A 1 386 ? 172.773 163.628 144.372 1.00 40.36  ? 412 LYS   A CB  1 
ATOM   3102 C CG  . LYS   A 1 386 ? 173.789 164.437 145.162 1.00 41.30  ? 412 LYS   A CG  1 
ATOM   3103 C CD  . LYS   A 1 386 ? 174.740 165.195 144.261 1.00 42.44  ? 412 LYS   A CD  1 
ATOM   3104 C CE  . LYS   A 1 386 ? 174.069 166.373 143.589 1.00 42.95  ? 412 LYS   A CE  1 
ATOM   3105 N NZ  . LYS   A 1 386 ? 175.032 167.182 142.798 1.00 49.12  ? 412 LYS   A NZ  1 
ATOM   3106 N N   . ILE   A 1 387 ? 171.489 163.499 147.496 1.00 38.49  ? 413 ILE   A N   1 
ATOM   3107 C CA  . ILE   A 1 387 ? 170.884 164.277 148.572 1.00 36.59  ? 413 ILE   A CA  1 
ATOM   3108 C C   . ILE   A 1 387 ? 171.978 165.147 149.168 1.00 36.78  ? 413 ILE   A C   1 
ATOM   3109 O O   . ILE   A 1 387 ? 172.945 164.628 149.737 1.00 42.69  ? 413 ILE   A O   1 
ATOM   3110 C CB  . ILE   A 1 387 ? 170.250 163.381 149.650 1.00 38.34  ? 413 ILE   A CB  1 
ATOM   3111 C CG1 . ILE   A 1 387 ? 169.126 162.523 149.060 1.00 37.40  ? 413 ILE   A CG1 1 
ATOM   3112 C CG2 . ILE   A 1 387 ? 169.726 164.243 150.797 1.00 40.39  ? 413 ILE   A CG2 1 
ATOM   3113 C CD1 . ILE   A 1 387 ? 168.691 161.379 149.942 1.00 34.96  ? 413 ILE   A CD1 1 
ATOM   3114 N N   . THR   A 1 388 ? 171.824 166.461 149.042 1.00 37.69  ? 414 THR   A N   1 
ATOM   3115 C CA  . THR   A 1 388 ? 172.797 167.432 149.522 1.00 39.98  ? 414 THR   A CA  1 
ATOM   3116 C C   . THR   A 1 388 ? 172.199 168.214 150.678 1.00 42.60  ? 414 THR   A C   1 
ATOM   3117 O O   . THR   A 1 388 ? 170.996 168.487 150.690 1.00 47.22  ? 414 THR   A O   1 
ATOM   3118 C CB  . THR   A 1 388 ? 173.202 168.398 148.407 1.00 41.20  ? 414 THR   A CB  1 
ATOM   3119 O OG1 . THR   A 1 388 ? 173.597 167.656 147.247 1.00 48.60  ? 414 THR   A OG1 1 
ATOM   3120 C CG2 . THR   A 1 388 ? 174.350 169.287 148.852 1.00 42.43  ? 414 THR   A CG2 1 
ATOM   3121 N N   . TYR   A 1 389 ? 173.036 168.565 151.653 1.00 43.11  ? 415 TYR   A N   1 
ATOM   3122 C CA  . TYR   A 1 389 ? 172.611 169.356 152.799 1.00 45.83  ? 415 TYR   A CA  1 
ATOM   3123 C C   . TYR   A 1 389 ? 173.600 170.482 153.046 1.00 49.51  ? 415 TYR   A C   1 
ATOM   3124 O O   . TYR   A 1 389 ? 174.815 170.302 152.905 1.00 55.60  ? 415 TYR   A O   1 
ATOM   3125 C CB  . TYR   A 1 389 ? 172.458 168.496 154.070 1.00 47.75  ? 415 TYR   A CB  1 
ATOM   3126 C CG  . TYR   A 1 389 ? 173.749 168.102 154.756 1.00 46.12  ? 415 TYR   A CG  1 
ATOM   3127 C CD1 . TYR   A 1 389 ? 174.424 166.951 154.391 1.00 44.49  ? 415 TYR   A CD1 1 
ATOM   3128 C CD2 . TYR   A 1 389 ? 174.277 168.868 155.786 1.00 48.23  ? 415 TYR   A CD2 1 
ATOM   3129 C CE1 . TYR   A 1 389 ? 175.590 166.581 155.016 1.00 45.44  ? 415 TYR   A CE1 1 
ATOM   3130 C CE2 . TYR   A 1 389 ? 175.449 168.508 156.412 1.00 49.58  ? 415 TYR   A CE2 1 
ATOM   3131 C CZ  . TYR   A 1 389 ? 176.101 167.363 156.023 1.00 49.74  ? 415 TYR   A CZ  1 
ATOM   3132 O OH  . TYR   A 1 389 ? 177.268 166.996 156.649 1.00 59.50  ? 415 TYR   A OH  1 
ATOM   3133 N N   . ARG   A 1 390 ? 173.065 171.644 153.414 1.00 47.62  ? 416 ARG   A N   1 
ATOM   3134 C CA  . ARG   A 1 390 ? 173.849 172.796 153.830 1.00 51.38  ? 416 ARG   A CA  1 
ATOM   3135 C C   . ARG   A 1 390 ? 173.556 173.076 155.295 1.00 56.10  ? 416 ARG   A C   1 
ATOM   3136 O O   . ARG   A 1 390 ? 172.396 173.256 155.676 1.00 55.63  ? 416 ARG   A O   1 
ATOM   3137 C CB  . ARG   A 1 390 ? 173.529 174.024 152.971 1.00 52.47  ? 416 ARG   A CB  1 
ATOM   3138 C CG  . ARG   A 1 390 ? 174.255 175.293 153.402 1.00 55.23  ? 416 ARG   A CG  1 
ATOM   3139 C CD  . ARG   A 1 390 ? 174.093 176.429 152.404 1.00 53.07  ? 416 ARG   A CD  1 
ATOM   3140 N NE  . ARG   A 1 390 ? 175.125 176.417 151.372 1.00 54.70  ? 416 ARG   A NE  1 
ATOM   3141 C CZ  . ARG   A 1 390 ? 175.025 175.846 150.177 1.00 58.84  ? 416 ARG   A CZ  1 
ATOM   3142 N NH1 . ARG   A 1 390 ? 173.934 175.196 149.799 1.00 57.40  ? 416 ARG   A NH1 1 
ATOM   3143 N NH2 . ARG   A 1 390 ? 176.049 175.931 149.334 1.00 62.28  ? 416 ARG   A NH2 1 
ATOM   3144 N N   . ASP   A 1 391 ? 174.606 173.117 156.107 1.00 60.05  ? 417 ASP   A N   1 
ATOM   3145 C CA  . ASP   A 1 391 ? 174.442 173.364 157.531 1.00 58.34  ? 417 ASP   A CA  1 
ATOM   3146 C C   . ASP   A 1 391 ? 173.977 174.793 157.768 1.00 59.25  ? 417 ASP   A C   1 
ATOM   3147 O O   . ASP   A 1 391 ? 174.430 175.729 157.104 1.00 61.90  ? 417 ASP   A O   1 
ATOM   3148 C CB  . ASP   A 1 391 ? 175.758 173.106 158.262 1.00 61.83  ? 417 ASP   A CB  1 
ATOM   3149 C CG  . ASP   A 1 391 ? 175.621 173.216 159.764 1.00 67.94  ? 417 ASP   A CG  1 
ATOM   3150 O OD1 . ASP   A 1 391 ? 174.944 172.357 160.365 1.00 69.55  ? 417 ASP   A OD1 1 
ATOM   3151 O OD2 . ASP   A 1 391 ? 176.192 174.162 160.347 1.00 73.58  ? 417 ASP   A OD2 1 
ATOM   3152 N N   . GLY   A 1 392 ? 173.072 174.959 158.723 1.00 59.30  ? 418 GLY   A N   1 
ATOM   3153 C CA  . GLY   A 1 392 ? 172.474 176.245 159.003 1.00 59.91  ? 418 GLY   A CA  1 
ATOM   3154 C C   . GLY   A 1 392 ? 173.252 177.146 159.929 1.00 62.70  ? 418 GLY   A C   1 
ATOM   3155 O O   . GLY   A 1 392 ? 172.772 178.238 160.248 1.00 64.60  ? 418 GLY   A O   1 
ATOM   3156 N N   . ARG   A 1 393 ? 174.433 176.727 160.377 1.00 65.99  ? 419 ARG   A N   1 
ATOM   3157 C CA  . ARG   A 1 393 ? 175.312 177.528 161.222 1.00 68.15  ? 419 ARG   A CA  1 
ATOM   3158 C C   . ARG   A 1 393 ? 176.650 177.828 160.569 1.00 67.30  ? 419 ARG   A C   1 
ATOM   3159 O O   . ARG   A 1 393 ? 177.099 178.976 160.599 1.00 64.44  ? 419 ARG   A O   1 
ATOM   3160 C CB  . ARG   A 1 393 ? 175.545 176.800 162.556 1.00 72.34  ? 419 ARG   A CB  1 
ATOM   3161 C CG  . ARG   A 1 393 ? 176.358 177.579 163.588 1.00 78.50  ? 419 ARG   A CG  1 
ATOM   3162 C CD  . ARG   A 1 393 ? 176.517 176.787 164.878 1.00 85.66  ? 419 ARG   A CD  1 
ATOM   3163 N NE  . ARG   A 1 393 ? 177.250 175.543 164.670 1.00 90.67  ? 419 ARG   A NE  1 
ATOM   3164 C CZ  . ARG   A 1 393 ? 177.522 174.653 165.617 1.00 95.83  ? 419 ARG   A CZ  1 
ATOM   3165 N NH1 . ARG   A 1 393 ? 177.142 174.832 166.873 1.00 96.69  ? 419 ARG   A NH1 1 
ATOM   3166 N NH2 . ARG   A 1 393 ? 178.194 173.551 165.295 1.00 94.13  ? 419 ARG   A NH2 1 
ATOM   3167 N N   . THR   A 1 394 ? 177.289 176.828 159.965 1.00 65.66  ? 420 THR   A N   1 
ATOM   3168 C CA  . THR   A 1 394 ? 178.639 176.962 159.432 1.00 66.52  ? 420 THR   A CA  1 
ATOM   3169 C C   . THR   A 1 394 ? 178.670 177.179 157.928 1.00 67.69  ? 420 THR   A C   1 
ATOM   3170 O O   . THR   A 1 394 ? 179.628 177.772 157.422 1.00 70.83  ? 420 THR   A O   1 
ATOM   3171 C CB  . THR   A 1 394 ? 179.464 175.713 159.767 1.00 72.72  ? 420 THR   A CB  1 
ATOM   3172 O OG1 . THR   A 1 394 ? 179.276 175.370 161.146 1.00 75.00  ? 420 THR   A OG1 1 
ATOM   3173 C CG2 . THR   A 1 394 ? 180.948 175.956 159.511 1.00 73.95  ? 420 THR   A CG2 1 
ATOM   3174 N N   . GLY   A 1 395 ? 177.655 176.713 157.205 1.00 64.08  ? 421 GLY   A N   1 
ATOM   3175 C CA  . GLY   A 1 395 ? 177.618 176.827 155.765 1.00 57.43  ? 421 GLY   A CA  1 
ATOM   3176 C C   . GLY   A 1 395 ? 178.262 175.682 155.020 1.00 55.60  ? 421 GLY   A C   1 
ATOM   3177 O O   . GLY   A 1 395 ? 178.285 175.710 153.783 1.00 57.95  ? 421 GLY   A O   1 
ATOM   3178 N N   . GLU   A 1 396 ? 178.782 174.679 155.722 1.00 56.98  ? 422 GLU   A N   1 
ATOM   3179 C CA  . GLU   A 1 396 ? 179.394 173.540 155.058 1.00 58.81  ? 422 GLU   A CA  1 
ATOM   3180 C C   . GLU   A 1 396 ? 178.352 172.770 154.259 1.00 56.73  ? 422 GLU   A C   1 
ATOM   3181 O O   . GLU   A 1 396 ? 177.176 172.708 154.625 1.00 60.63  ? 422 GLU   A O   1 
ATOM   3182 C CB  . GLU   A 1 396 ? 180.053 172.613 156.078 1.00 68.45  ? 422 GLU   A CB  1 
ATOM   3183 C CG  . GLU   A 1 396 ? 181.200 173.248 156.847 1.00 73.97  ? 422 GLU   A CG  1 
ATOM   3184 C CD  . GLU   A 1 396 ? 181.885 172.270 157.782 1.00 78.81  ? 422 GLU   A CD  1 
ATOM   3185 O OE1 . GLU   A 1 396 ? 181.514 171.077 157.774 1.00 77.22  ? 422 GLU   A OE1 1 
ATOM   3186 O OE2 . GLU   A 1 396 ? 182.795 172.694 158.524 1.00 80.06  ? 422 GLU   A OE2 1 
ATOM   3187 N N   . LEU   A 1 397 ? 178.802 172.176 153.157 1.00 51.56  ? 423 LEU   A N   1 
ATOM   3188 C CA  . LEU   A 1 397 ? 177.949 171.443 152.232 1.00 48.62  ? 423 LEU   A CA  1 
ATOM   3189 C C   . LEU   A 1 397 ? 178.385 169.988 152.220 1.00 47.75  ? 423 LEU   A C   1 
ATOM   3190 O O   . LEU   A 1 397 ? 179.569 169.697 152.025 1.00 53.42  ? 423 LEU   A O   1 
ATOM   3191 C CB  . LEU   A 1 397 ? 178.030 172.040 150.826 1.00 50.10  ? 423 LEU   A CB  1 
ATOM   3192 C CG  . LEU   A 1 397 ? 176.873 171.754 149.866 1.00 53.50  ? 423 LEU   A CG  1 
ATOM   3193 C CD1 . LEU   A 1 397 ? 175.577 172.396 150.343 1.00 55.58  ? 423 LEU   A CD1 1 
ATOM   3194 C CD2 . LEU   A 1 397 ? 177.217 172.228 148.461 1.00 53.14  ? 423 LEU   A CD2 1 
ATOM   3195 N N   . GLY   A 1 398 ? 177.428 169.078 152.432 1.00 45.99  ? 424 GLY   A N   1 
ATOM   3196 C CA  . GLY   A 1 398 ? 177.724 167.666 152.515 1.00 47.95  ? 424 GLY   A CA  1 
ATOM   3197 C C   . GLY   A 1 398 ? 176.676 166.843 151.787 1.00 48.54  ? 424 GLY   A C   1 
ATOM   3198 O O   . GLY   A 1 398 ? 175.642 167.356 151.354 1.00 53.46  ? 424 GLY   A O   1 
ATOM   3199 N N   . TYR   A 1 399 ? 176.969 165.550 151.662 1.00 40.84  ? 425 TYR   A N   1 
ATOM   3200 C CA  . TYR   A 1 399 ? 176.181 164.631 150.853 1.00 38.62  ? 425 TYR   A CA  1 
ATOM   3201 C C   . TYR   A 1 399 ? 175.866 163.387 151.666 1.00 37.40  ? 425 TYR   A C   1 
ATOM   3202 O O   . TYR   A 1 399 ? 176.769 162.785 152.254 1.00 45.59  ? 425 TYR   A O   1 
ATOM   3203 C CB  . TYR   A 1 399 ? 176.934 164.263 149.571 1.00 42.30  ? 425 TYR   A CB  1 
ATOM   3204 C CG  . TYR   A 1 399 ? 177.308 165.461 148.729 1.00 42.51  ? 425 TYR   A CG  1 
ATOM   3205 C CD1 . TYR   A 1 399 ? 178.470 166.174 148.976 1.00 43.00  ? 425 TYR   A CD1 1 
ATOM   3206 C CD2 . TYR   A 1 399 ? 176.500 165.878 147.687 1.00 43.34  ? 425 TYR   A CD2 1 
ATOM   3207 C CE1 . TYR   A 1 399 ? 178.811 167.267 148.216 1.00 43.51  ? 425 TYR   A CE1 1 
ATOM   3208 C CE2 . TYR   A 1 399 ? 176.834 166.973 146.920 1.00 47.52  ? 425 TYR   A CE2 1 
ATOM   3209 C CZ  . TYR   A 1 399 ? 177.991 167.662 147.189 1.00 46.30  ? 425 TYR   A CZ  1 
ATOM   3210 O OH  . TYR   A 1 399 ? 178.330 168.753 146.425 1.00 51.47  ? 425 TYR   A OH  1 
ATOM   3211 N N   . LEU   A 1 400 ? 174.592 163.011 151.702 1.00 36.78  ? 426 LEU   A N   1 
ATOM   3212 C CA  . LEU   A 1 400 ? 174.123 161.842 152.431 1.00 41.03  ? 426 LEU   A CA  1 
ATOM   3213 C C   . LEU   A 1 400 ? 173.980 160.652 151.491 1.00 44.75  ? 426 LEU   A C   1 
ATOM   3214 O O   . LEU   A 1 400 ? 174.025 160.784 150.266 1.00 46.47  ? 426 LEU   A O   1 
ATOM   3215 C CB  . LEU   A 1 400 ? 172.783 162.128 153.118 1.00 38.64  ? 426 LEU   A CB  1 
ATOM   3216 C CG  . LEU   A 1 400 ? 172.700 163.341 154.048 1.00 39.83  ? 426 LEU   A CG  1 
ATOM   3217 C CD1 . LEU   A 1 400 ? 171.323 163.421 154.667 1.00 39.44  ? 426 LEU   A CD1 1 
ATOM   3218 C CD2 . LEU   A 1 400 ? 173.766 163.287 155.129 1.00 44.23  ? 426 LEU   A CD2 1 
ATOM   3219 N N   . ASN   A 1 401 ? 173.807 159.473 152.081 1.00 42.68  ? 427 ASN   A N   1 
ATOM   3220 C CA  . ASN   A 1 401 ? 173.525 158.295 151.276 1.00 40.95  ? 427 ASN   A CA  1 
ATOM   3221 C C   . ASN   A 1 401 ? 172.127 158.417 150.670 1.00 41.79  ? 427 ASN   A C   1 
ATOM   3222 O O   . ASN   A 1 401 ? 171.259 159.068 151.259 1.00 45.15  ? 427 ASN   A O   1 
ATOM   3223 C CB  . ASN   A 1 401 ? 173.623 157.021 152.114 1.00 38.30  ? 427 ASN   A CB  1 
ATOM   3224 C CG  . ASN   A 1 401 ? 175.053 156.587 152.364 1.00 44.02  ? 427 ASN   A CG  1 
ATOM   3225 O OD1 . ASN   A 1 401 ? 175.949 156.854 151.566 1.00 50.89  ? 427 ASN   A OD1 1 
ATOM   3226 N ND2 . ASN   A 1 401 ? 175.271 155.899 153.475 1.00 44.38  ? 427 ASN   A ND2 1 
ATOM   3227 N N   . PRO   A 1 402 ? 171.881 157.832 149.487 1.00 40.79  ? 428 PRO   A N   1 
ATOM   3228 C CA  . PRO   A 1 402 ? 170.557 158.012 148.864 1.00 39.07  ? 428 PRO   A CA  1 
ATOM   3229 C C   . PRO   A 1 402 ? 169.390 157.518 149.702 1.00 40.32  ? 428 PRO   A C   1 
ATOM   3230 O O   . PRO   A 1 402 ? 168.367 158.208 149.780 1.00 49.69  ? 428 PRO   A O   1 
ATOM   3231 C CB  . PRO   A 1 402 ? 170.678 157.218 147.559 1.00 42.89  ? 428 PRO   A CB  1 
ATOM   3232 C CG  . PRO   A 1 402 ? 172.116 157.169 147.272 1.00 47.01  ? 428 PRO   A CG  1 
ATOM   3233 C CD  . PRO   A 1 402 ? 172.796 157.096 148.594 1.00 46.07  ? 428 PRO   A CD  1 
ATOM   3234 N N   . GLY   A 1 403 ? 169.522 156.364 150.352 1.00 37.11  ? 429 GLY   A N   1 
ATOM   3235 C CA  . GLY   A 1 403 ? 168.402 155.705 151.003 1.00 38.55  ? 429 GLY   A CA  1 
ATOM   3236 C C   . GLY   A 1 403 ? 168.542 155.534 152.501 1.00 38.93  ? 429 GLY   A C   1 
ATOM   3237 O O   . GLY   A 1 403 ? 168.183 154.481 153.036 1.00 40.79  ? 429 GLY   A O   1 
ATOM   3238 N N   . VAL   A 1 404 ? 169.058 156.541 153.192 1.00 37.89  ? 430 VAL   A N   1 
ATOM   3239 C CA  . VAL   A 1 404 ? 169.335 156.419 154.618 1.00 35.76  ? 430 VAL   A CA  1 
ATOM   3240 C C   . VAL   A 1 404 ? 168.043 156.575 155.407 1.00 41.85  ? 430 VAL   A C   1 
ATOM   3241 O O   . VAL   A 1 404 ? 167.161 157.361 155.041 1.00 45.72  ? 430 VAL   A O   1 
ATOM   3242 C CB  . VAL   A 1 404 ? 170.386 157.456 155.048 1.00 36.44  ? 430 VAL   A CB  1 
ATOM   3243 C CG1 . VAL   A 1 404 ? 169.798 158.857 155.061 1.00 38.81  ? 430 VAL   A CG1 1 
ATOM   3244 C CG2 . VAL   A 1 404 ? 170.962 157.101 156.406 1.00 40.32  ? 430 VAL   A CG2 1 
ATOM   3245 N N   . PHE   A 1 405 ? 167.933 155.820 156.503 1.00 41.54  ? 431 PHE   A N   1 
ATOM   3246 C CA  . PHE   A 1 405 ? 166.773 155.877 157.396 1.00 39.26  ? 431 PHE   A CA  1 
ATOM   3247 C C   . PHE   A 1 405 ? 165.481 155.547 156.657 1.00 42.20  ? 431 PHE   A C   1 
ATOM   3248 O O   . PHE   A 1 405 ? 164.444 156.173 156.884 1.00 48.13  ? 431 PHE   A O   1 
ATOM   3249 C CB  . PHE   A 1 405 ? 166.657 157.245 158.071 1.00 40.80  ? 431 PHE   A CB  1 
ATOM   3250 C CG  . PHE   A 1 405 ? 167.866 157.653 158.868 1.00 44.02  ? 431 PHE   A CG  1 
ATOM   3251 C CD1 . PHE   A 1 405 ? 168.586 156.735 159.608 1.00 49.71  ? 431 PHE   A CD1 1 
ATOM   3252 C CD2 . PHE   A 1 405 ? 168.267 158.974 158.889 1.00 44.97  ? 431 PHE   A CD2 1 
ATOM   3253 C CE1 . PHE   A 1 405 ? 169.685 157.127 160.340 1.00 48.39  ? 431 PHE   A CE1 1 
ATOM   3254 C CE2 . PHE   A 1 405 ? 169.363 159.368 159.618 1.00 44.61  ? 431 PHE   A CE2 1 
ATOM   3255 C CZ  . PHE   A 1 405 ? 170.071 158.446 160.344 1.00 46.87  ? 431 PHE   A CZ  1 
ATOM   3256 N N   . THR   A 1 406 ? 165.539 154.564 155.762 1.00 39.41  ? 432 THR   A N   1 
ATOM   3257 C CA  . THR   A 1 406 ? 164.388 154.197 154.950 1.00 40.01  ? 432 THR   A CA  1 
ATOM   3258 C C   . THR   A 1 406 ? 164.389 152.695 154.715 1.00 43.69  ? 432 THR   A C   1 
ATOM   3259 O O   . THR   A 1 406 ? 165.423 152.030 154.813 1.00 48.02  ? 432 THR   A O   1 
ATOM   3260 C CB  . THR   A 1 406 ? 164.389 154.938 153.609 1.00 41.47  ? 432 THR   A CB  1 
ATOM   3261 O OG1 . THR   A 1 406 ? 164.915 156.256 153.793 1.00 44.83  ? 432 THR   A OG1 1 
ATOM   3262 C CG2 . THR   A 1 406 ? 162.985 155.047 153.049 1.00 43.89  ? 432 THR   A CG2 1 
ATOM   3263 N N   . GLN   A 1 407 ? 163.201 152.170 154.407 1.00 44.90  ? 433 GLN   A N   1 
ATOM   3264 C CA  . GLN   A 1 407 ? 162.999 150.752 154.155 1.00 45.13  ? 433 GLN   A CA  1 
ATOM   3265 C C   . GLN   A 1 407 ? 162.429 150.446 152.777 1.00 45.03  ? 433 GLN   A C   1 
ATOM   3266 O O   . GLN   A 1 407 ? 162.417 149.274 152.385 1.00 49.13  ? 433 GLN   A O   1 
ATOM   3267 C CB  . GLN   A 1 407 ? 162.065 150.156 155.219 1.00 45.72  ? 433 GLN   A CB  1 
ATOM   3268 C CG  . GLN   A 1 407 ? 162.541 150.375 156.641 1.00 46.20  ? 433 GLN   A CG  1 
ATOM   3269 C CD  . GLN   A 1 407 ? 161.620 149.755 157.661 1.00 46.74  ? 433 GLN   A CD  1 
ATOM   3270 O OE1 . GLN   A 1 407 ? 160.778 148.924 157.330 1.00 47.26  ? 433 GLN   A OE1 1 
ATOM   3271 N NE2 . GLN   A 1 407 ? 161.769 150.160 158.912 1.00 44.51  ? 433 GLN   A NE2 1 
ATOM   3272 N N   . SER   A 1 408 ? 161.956 151.449 152.041 1.00 42.26  ? 434 SER   A N   1 
ATOM   3273 C CA  . SER   A 1 408 ? 161.443 151.285 150.690 1.00 42.91  ? 434 SER   A CA  1 
ATOM   3274 C C   . SER   A 1 408 ? 162.107 152.299 149.771 1.00 44.34  ? 434 SER   A C   1 
ATOM   3275 O O   . SER   A 1 408 ? 162.764 153.242 150.218 1.00 45.54  ? 434 SER   A O   1 
ATOM   3276 C CB  . SER   A 1 408 ? 159.923 151.455 150.644 1.00 48.00  ? 434 SER   A CB  1 
ATOM   3277 O OG  . SER   A 1 408 ? 159.447 151.346 149.314 1.00 56.18  ? 434 SER   A OG  1 
ATOM   3278 N N   . ARG   A 1 409 ? 161.924 152.087 148.467 1.00 46.76  ? 435 ARG   A N   1 
ATOM   3279 C CA  . ARG   A 1 409 ? 162.480 152.947 147.429 1.00 48.90  ? 435 ARG   A CA  1 
ATOM   3280 C C   . ARG   A 1 409 ? 161.393 153.636 146.610 1.00 48.97  ? 435 ARG   A C   1 
ATOM   3281 O O   . ARG   A 1 409 ? 161.648 154.040 145.472 1.00 51.92  ? 435 ARG   A O   1 
ATOM   3282 C CB  . ARG   A 1 409 ? 163.403 152.140 146.514 1.00 57.66  ? 435 ARG   A CB  1 
ATOM   3283 C CG  . ARG   A 1 409 ? 162.731 150.962 145.816 1.00 65.27  ? 435 ARG   A CG  1 
ATOM   3284 C CD  . ARG   A 1 409 ? 163.711 150.184 144.951 1.00 74.50  ? 435 ARG   A CD  1 
ATOM   3285 N NE  . ARG   A 1 409 ? 164.761 149.551 145.741 1.00 79.76  ? 435 ARG   A NE  1 
ATOM   3286 C CZ  . ARG   A 1 409 ? 165.735 148.798 145.246 1.00 85.89  ? 435 ARG   A CZ  1 
ATOM   3287 N NH1 . ARG   A 1 409 ? 165.836 148.553 143.948 1.00 85.84  ? 435 ARG   A NH1 1 
ATOM   3288 N NH2 . ARG   A 1 409 ? 166.634 148.275 146.075 1.00 85.79  ? 435 ARG   A NH2 1 
ATOM   3289 N N   . ARG   A 1 410 ? 160.190 153.784 147.162 1.00 45.83  ? 436 ARG   A N   1 
ATOM   3290 C CA  . ARG   A 1 410 ? 159.102 154.483 146.491 1.00 43.34  ? 436 ARG   A CA  1 
ATOM   3291 C C   . ARG   A 1 410 ? 159.067 155.973 146.795 1.00 41.88  ? 436 ARG   A C   1 
ATOM   3292 O O   . ARG   A 1 410 ? 158.257 156.690 146.199 1.00 46.25  ? 436 ARG   A O   1 
ATOM   3293 C CB  . ARG   A 1 410 ? 157.756 153.871 146.883 1.00 48.56  ? 436 ARG   A CB  1 
ATOM   3294 C CG  . ARG   A 1 410 ? 157.386 152.606 146.144 1.00 50.42  ? 436 ARG   A CG  1 
ATOM   3295 C CD  . ARG   A 1 410 ? 155.927 152.277 146.389 1.00 52.04  ? 436 ARG   A CD  1 
ATOM   3296 N NE  . ARG   A 1 410 ? 155.517 151.027 145.765 1.00 55.67  ? 436 ARG   A NE  1 
ATOM   3297 C CZ  . ARG   A 1 410 ? 154.275 150.563 145.752 1.00 59.83  ? 436 ARG   A CZ  1 
ATOM   3298 N NH1 . ARG   A 1 410 ? 153.277 151.226 146.317 1.00 58.52  ? 436 ARG   A NH1 1 
ATOM   3299 N NH2 . ARG   A 1 410 ? 154.023 149.402 145.153 1.00 61.86  ? 436 ARG   A NH2 1 
ATOM   3300 N N   . TRP   A 1 411 ? 159.915 156.461 147.696 1.00 36.94  ? 437 TRP   A N   1 
ATOM   3301 C CA  . TRP   A 1 411 ? 159.970 157.891 147.972 1.00 36.96  ? 437 TRP   A CA  1 
ATOM   3302 C C   . TRP   A 1 411 ? 160.582 158.693 146.832 1.00 42.65  ? 437 TRP   A C   1 
ATOM   3303 O O   . TRP   A 1 411 ? 160.525 159.926 146.870 1.00 48.23  ? 437 TRP   A O   1 
ATOM   3304 C CB  . TRP   A 1 411 ? 160.757 158.151 149.258 1.00 37.61  ? 437 TRP   A CB  1 
ATOM   3305 C CG  . TRP   A 1 411 ? 162.166 157.664 149.211 1.00 39.94  ? 437 TRP   A CG  1 
ATOM   3306 C CD1 . TRP   A 1 411 ? 162.623 156.454 149.630 1.00 42.94  ? 437 TRP   A CD1 1 
ATOM   3307 C CD2 . TRP   A 1 411 ? 163.303 158.371 148.708 1.00 40.50  ? 437 TRP   A CD2 1 
ATOM   3308 N NE1 . TRP   A 1 411 ? 163.974 156.361 149.423 1.00 43.07  ? 437 TRP   A NE1 1 
ATOM   3309 C CE2 . TRP   A 1 411 ? 164.415 157.526 148.855 1.00 38.13  ? 437 TRP   A CE2 1 
ATOM   3310 C CE3 . TRP   A 1 411 ? 163.487 159.635 148.145 1.00 43.02  ? 437 TRP   A CE3 1 
ATOM   3311 C CZ2 . TRP   A 1 411 ? 165.689 157.902 148.463 1.00 38.85  ? 437 TRP   A CZ2 1 
ATOM   3312 C CZ3 . TRP   A 1 411 ? 164.753 160.006 147.758 1.00 41.29  ? 437 TRP   A CZ3 1 
ATOM   3313 C CH2 . TRP   A 1 411 ? 165.838 159.144 147.918 1.00 40.13  ? 437 TRP   A CH2 1 
ATOM   3314 N N   . LYS   A 1 412 ? 161.160 158.037 145.827 1.00 44.00  ? 438 LYS   A N   1 
ATOM   3315 C CA  . LYS   A 1 412 ? 161.860 158.727 144.755 1.00 43.43  ? 438 LYS   A CA  1 
ATOM   3316 C C   . LYS   A 1 412 ? 160.931 159.298 143.693 1.00 46.38  ? 438 LYS   A C   1 
ATOM   3317 O O   . LYS   A 1 412 ? 161.410 160.015 142.808 1.00 47.94  ? 438 LYS   A O   1 
ATOM   3318 C CB  . LYS   A 1 412 ? 162.847 157.771 144.080 1.00 43.53  ? 438 LYS   A CB  1 
ATOM   3319 C CG  . LYS   A 1 412 ? 163.888 157.174 145.002 1.00 45.96  ? 438 LYS   A CG  1 
ATOM   3320 C CD  . LYS   A 1 412 ? 164.769 156.190 144.260 1.00 45.67  ? 438 LYS   A CD  1 
ATOM   3321 C CE  . LYS   A 1 412 ? 165.852 155.634 145.155 1.00 48.15  ? 438 LYS   A CE  1 
ATOM   3322 N NZ  . LYS   A 1 412 ? 166.756 154.715 144.420 1.00 49.45  ? 438 LYS   A NZ  1 
ATOM   3323 N N   . ASP   A 1 413 ? 159.627 159.007 143.757 1.00 49.15  ? 439 ASP   A N   1 
ATOM   3324 C CA  . ASP   A 1 413 ? 158.703 159.310 142.672 1.00 50.39  ? 439 ASP   A CA  1 
ATOM   3325 C C   . ASP   A 1 413 ? 157.458 160.075 143.096 1.00 51.00  ? 439 ASP   A C   1 
ATOM   3326 O O   . ASP   A 1 413 ? 156.608 160.342 142.239 1.00 54.70  ? 439 ASP   A O   1 
ATOM   3327 C CB  . ASP   A 1 413 ? 158.262 158.012 141.982 1.00 49.98  ? 439 ASP   A CB  1 
ATOM   3328 C CG  . ASP   A 1 413 ? 159.429 157.185 141.501 1.00 53.46  ? 439 ASP   A CG  1 
ATOM   3329 O OD1 . ASP   A 1 413 ? 160.465 157.774 141.131 1.00 50.58  ? 439 ASP   A OD1 1 
ATOM   3330 O OD2 . ASP   A 1 413 ? 159.313 155.942 141.493 1.00 59.41  ? 439 ASP   A OD2 1 
ATOM   3331 N N   . HIS   A 1 414 ? 157.316 160.429 144.372 1.00 44.00  ? 440 HIS   A N   1 
ATOM   3332 C CA  . HIS   A 1 414 ? 156.126 161.105 144.870 1.00 44.49  ? 440 HIS   A CA  1 
ATOM   3333 C C   . HIS   A 1 414 ? 156.524 162.288 145.739 1.00 46.83  ? 440 HIS   A C   1 
ATOM   3334 O O   . HIS   A 1 414 ? 157.439 162.187 146.561 1.00 48.48  ? 440 HIS   A O   1 
ATOM   3335 C CB  . HIS   A 1 414 ? 155.242 160.131 145.651 1.00 49.41  ? 440 HIS   A CB  1 
ATOM   3336 C CG  . HIS   A 1 414 ? 154.794 158.952 144.844 1.00 50.48  ? 440 HIS   A CG  1 
ATOM   3337 N ND1 . HIS   A 1 414 ? 155.578 157.834 144.661 1.00 48.56  ? 440 HIS   A ND1 1 
ATOM   3338 C CD2 . HIS   A 1 414 ? 153.648 158.723 144.160 1.00 53.40  ? 440 HIS   A CD2 1 
ATOM   3339 C CE1 . HIS   A 1 414 ? 154.932 156.964 143.905 1.00 50.35  ? 440 HIS   A CE1 1 
ATOM   3340 N NE2 . HIS   A 1 414 ? 153.759 157.480 143.586 1.00 53.21  ? 440 HIS   A NE2 1 
ATOM   3341 N N   . ALA   A 1 415 ? 155.828 163.411 145.547 1.00 44.16  ? 441 ALA   A N   1 
ATOM   3342 C CA  . ALA   A 1 415 ? 156.192 164.645 146.238 1.00 44.57  ? 441 ALA   A CA  1 
ATOM   3343 C C   . ALA   A 1 415 ? 155.901 164.566 147.731 1.00 44.83  ? 441 ALA   A C   1 
ATOM   3344 O O   . ALA   A 1 415 ? 156.696 165.046 148.548 1.00 47.72  ? 441 ALA   A O   1 
ATOM   3345 C CB  . ALA   A 1 415 ? 155.452 165.827 145.616 1.00 46.75  ? 441 ALA   A CB  1 
ATOM   3346 N N   . ASP   A 1 416 ? 154.759 163.985 148.106 1.00 42.22  ? 442 ASP   A N   1 
ATOM   3347 C CA  . ASP   A 1 416 ? 154.390 163.916 149.518 1.00 43.38  ? 442 ASP   A CA  1 
ATOM   3348 C C   . ASP   A 1 416 ? 155.389 163.086 150.316 1.00 46.27  ? 442 ASP   A C   1 
ATOM   3349 O O   . ASP   A 1 416 ? 155.810 163.484 151.412 1.00 47.29  ? 442 ASP   A O   1 
ATOM   3350 C CB  . ASP   A 1 416 ? 152.975 163.351 149.665 1.00 45.96  ? 442 ASP   A CB  1 
ATOM   3351 C CG  . ASP   A 1 416 ? 152.799 162.012 148.976 1.00 47.20  ? 442 ASP   A CG  1 
ATOM   3352 O OD1 . ASP   A 1 416 ? 153.323 161.846 147.858 1.00 42.07  ? 442 ASP   A OD1 1 
ATOM   3353 O OD2 . ASP   A 1 416 ? 152.133 161.127 149.552 1.00 56.18  ? 442 ASP   A OD2 1 
ATOM   3354 N N   . MET   A 1 417 ? 155.787 161.933 149.779 1.00 45.60  ? 443 MET   A N   1 
ATOM   3355 C CA  . MET   A 1 417 ? 156.764 161.099 150.465 1.00 43.64  ? 443 MET   A CA  1 
ATOM   3356 C C   . MET   A 1 417 ? 158.109 161.804 150.556 1.00 42.31  ? 443 MET   A C   1 
ATOM   3357 O O   . MET   A 1 417 ? 158.817 161.674 151.560 1.00 46.53  ? 443 MET   A O   1 
ATOM   3358 C CB  . MET   A 1 417 ? 156.895 159.757 149.746 1.00 44.97  ? 443 MET   A CB  1 
ATOM   3359 C CG  . MET   A 1 417 ? 155.619 158.928 149.776 1.00 44.78  ? 443 MET   A CG  1 
ATOM   3360 S SD  . MET   A 1 417 ? 155.673 157.463 148.736 1.00 45.89  ? 443 MET   A SD  1 
ATOM   3361 C CE  . MET   A 1 417 ? 156.909 156.489 149.584 1.00 46.90  ? 443 MET   A CE  1 
ATOM   3362 N N   . LEU   A 1 418 ? 158.474 162.558 149.520 1.00 40.34  ? 444 LEU   A N   1 
ATOM   3363 C CA  . LEU   A 1 418 ? 159.711 163.328 149.561 1.00 40.08  ? 444 LEU   A CA  1 
ATOM   3364 C C   . LEU   A 1 418 ? 159.670 164.380 150.663 1.00 41.18  ? 444 LEU   A C   1 
ATOM   3365 O O   . LEU   A 1 418 ? 160.656 164.575 151.384 1.00 43.98  ? 444 LEU   A O   1 
ATOM   3366 C CB  . LEU   A 1 418 ? 159.954 163.982 148.204 1.00 37.67  ? 444 LEU   A CB  1 
ATOM   3367 C CG  . LEU   A 1 418 ? 161.375 164.452 147.910 1.00 39.72  ? 444 LEU   A CG  1 
ATOM   3368 C CD1 . LEU   A 1 418 ? 162.295 163.269 147.658 1.00 41.61  ? 444 LEU   A CD1 1 
ATOM   3369 C CD2 . LEU   A 1 418 ? 161.381 165.400 146.730 1.00 44.17  ? 444 LEU   A CD2 1 
ATOM   3370 N N   . LYS   A 1 419 ? 158.538 165.070 150.807 1.00 40.39  ? 445 LYS   A N   1 
ATOM   3371 C CA  . LYS   A 1 419 ? 158.400 166.063 151.868 1.00 36.94  ? 445 LYS   A CA  1 
ATOM   3372 C C   . LYS   A 1 419 ? 158.503 165.414 153.243 1.00 40.61  ? 445 LYS   A C   1 
ATOM   3373 O O   . LYS   A 1 419 ? 159.177 165.939 154.143 1.00 45.49  ? 445 LYS   A O   1 
ATOM   3374 C CB  . LYS   A 1 419 ? 157.064 166.791 151.709 1.00 37.81  ? 445 LYS   A CB  1 
ATOM   3375 C CG  . LYS   A 1 419 ? 156.828 167.960 152.646 1.00 36.48  ? 445 LYS   A CG  1 
ATOM   3376 C CD  . LYS   A 1 419 ? 157.709 169.133 152.314 1.00 35.11  ? 445 LYS   A CD  1 
ATOM   3377 C CE  . LYS   A 1 419 ? 157.362 170.340 153.161 1.00 37.30  ? 445 LYS   A CE  1 
ATOM   3378 N NZ  . LYS   A 1 419 ? 157.589 170.098 154.609 1.00 39.36  ? 445 LYS   A NZ  1 
ATOM   3379 N N   . GLN   A 1 420 ? 157.846 164.266 153.422 1.00 40.58  ? 446 GLN   A N   1 
ATOM   3380 C CA  . GLN   A 1 420 ? 157.921 163.570 154.703 1.00 40.18  ? 446 GLN   A CA  1 
ATOM   3381 C C   . GLN   A 1 420 ? 159.346 163.127 155.004 1.00 43.44  ? 446 GLN   A C   1 
ATOM   3382 O O   . GLN   A 1 420 ? 159.812 163.232 156.145 1.00 48.53  ? 446 GLN   A O   1 
ATOM   3383 C CB  . GLN   A 1 420 ? 156.982 162.367 154.707 1.00 43.05  ? 446 GLN   A CB  1 
ATOM   3384 C CG  . GLN   A 1 420 ? 155.513 162.728 154.672 1.00 47.22  ? 446 GLN   A CG  1 
ATOM   3385 C CD  . GLN   A 1 420 ? 154.623 161.528 154.869 1.00 45.90  ? 446 GLN   A CD  1 
ATOM   3386 O OE1 . GLN   A 1 420 ? 154.945 160.630 155.639 1.00 48.67  ? 446 GLN   A OE1 1 
ATOM   3387 N NE2 . GLN   A 1 420 ? 153.498 161.501 154.171 1.00 45.85  ? 446 GLN   A NE2 1 
ATOM   3388 N N   . TYR   A 1 421 ? 160.050 162.622 153.991 1.00 42.31  ? 447 TYR   A N   1 
ATOM   3389 C CA  . TYR   A 1 421 ? 161.433 162.202 154.176 1.00 39.82  ? 447 TYR   A CA  1 
ATOM   3390 C C   . TYR   A 1 421 ? 162.318 163.380 154.549 1.00 40.57  ? 447 TYR   A C   1 
ATOM   3391 O O   . TYR   A 1 421 ? 163.206 163.256 155.402 1.00 44.85  ? 447 TYR   A O   1 
ATOM   3392 C CB  . TYR   A 1 421 ? 161.930 161.531 152.897 1.00 37.83  ? 447 TYR   A CB  1 
ATOM   3393 C CG  . TYR   A 1 421 ? 163.271 160.848 152.994 1.00 36.59  ? 447 TYR   A CG  1 
ATOM   3394 C CD1 . TYR   A 1 421 ? 163.530 159.911 153.978 1.00 39.21  ? 447 TYR   A CD1 1 
ATOM   3395 C CD2 . TYR   A 1 421 ? 164.264 161.109 152.070 1.00 37.66  ? 447 TYR   A CD2 1 
ATOM   3396 C CE1 . TYR   A 1 421 ? 164.746 159.282 154.056 1.00 38.10  ? 447 TYR   A CE1 1 
ATOM   3397 C CE2 . TYR   A 1 421 ? 165.482 160.481 152.139 1.00 38.87  ? 447 TYR   A CE2 1 
ATOM   3398 C CZ  . TYR   A 1 421 ? 165.717 159.569 153.134 1.00 37.89  ? 447 TYR   A CZ  1 
ATOM   3399 O OH  . TYR   A 1 421 ? 166.933 158.938 153.199 1.00 41.60  ? 447 TYR   A OH  1 
ATOM   3400 N N   . ALA   A 1 422 ? 162.098 164.531 153.913 1.00 38.60  ? 448 ALA   A N   1 
ATOM   3401 C CA  . ALA   A 1 422 ? 162.883 165.712 154.244 1.00 36.84  ? 448 ALA   A CA  1 
ATOM   3402 C C   . ALA   A 1 422 ? 162.651 166.137 155.686 1.00 41.66  ? 448 ALA   A C   1 
ATOM   3403 O O   . ALA   A 1 422 ? 163.602 166.468 156.404 1.00 47.73  ? 448 ALA   A O   1 
ATOM   3404 C CB  . ALA   A 1 422 ? 162.541 166.851 153.288 1.00 38.26  ? 448 ALA   A CB  1 
ATOM   3405 N N   . THR   A 1 423 ? 161.394 166.123 156.138 1.00 41.45  ? 449 THR   A N   1 
ATOM   3406 C CA  . THR   A 1 423 ? 161.115 166.487 157.526 1.00 38.29  ? 449 THR   A CA  1 
ATOM   3407 C C   . THR   A 1 423 ? 161.726 165.483 158.502 1.00 43.59  ? 449 THR   A C   1 
ATOM   3408 O O   . THR   A 1 423 ? 162.247 165.867 159.561 1.00 47.54  ? 449 THR   A O   1 
ATOM   3409 C CB  . THR   A 1 423 ? 159.609 166.601 157.743 1.00 37.60  ? 449 THR   A CB  1 
ATOM   3410 O OG1 . THR   A 1 423 ? 159.041 167.439 156.732 1.00 35.35  ? 449 THR   A OG1 1 
ATOM   3411 C CG2 . THR   A 1 423 ? 159.306 167.195 159.111 1.00 41.11  ? 449 THR   A CG2 1 
ATOM   3412 N N   . CYS   A 1 424 ? 161.669 164.192 158.165 1.00 44.58  ? 450 CYS   A N   1 
ATOM   3413 C CA  . CYS   A 1 424 ? 162.279 163.170 159.011 1.00 46.62  ? 450 CYS   A CA  1 
ATOM   3414 C C   . CYS   A 1 424 ? 163.782 163.388 159.135 1.00 51.02  ? 450 CYS   A C   1 
ATOM   3415 O O   . CYS   A 1 424 ? 164.349 163.316 160.234 1.00 52.82  ? 450 CYS   A O   1 
ATOM   3416 C CB  . CYS   A 1 424 ? 161.989 161.786 158.434 1.00 48.10  ? 450 CYS   A CB  1 
ATOM   3417 S SG  . CYS   A 1 424 ? 162.763 160.423 159.324 1.00 74.99  ? 450 CYS   A SG  1 
ATOM   3418 N N   . LEU   A 1 425 ? 164.448 163.657 158.011 1.00 48.86  ? 451 LEU   A N   1 
ATOM   3419 C CA  . LEU   A 1 425 ? 165.878 163.939 158.059 1.00 43.36  ? 451 LEU   A CA  1 
ATOM   3420 C C   . LEU   A 1 425 ? 166.154 165.196 158.864 1.00 45.29  ? 451 LEU   A C   1 
ATOM   3421 O O   . LEU   A 1 425 ? 167.154 165.271 159.586 1.00 51.66  ? 451 LEU   A O   1 
ATOM   3422 C CB  . LEU   A 1 425 ? 166.445 164.080 156.646 1.00 40.03  ? 451 LEU   A CB  1 
ATOM   3423 C CG  . LEU   A 1 425 ? 166.589 162.819 155.799 1.00 40.85  ? 451 LEU   A CG  1 
ATOM   3424 C CD1 . LEU   A 1 425 ? 167.097 163.187 154.422 1.00 42.00  ? 451 LEU   A CD1 1 
ATOM   3425 C CD2 . LEU   A 1 425 ? 167.519 161.816 156.449 1.00 44.15  ? 451 LEU   A CD2 1 
ATOM   3426 N N   . SER   A 1 426 ? 165.278 166.195 158.754 1.00 44.02  ? 452 SER   A N   1 
ATOM   3427 C CA  . SER   A 1 426 ? 165.463 167.421 159.517 1.00 45.69  ? 452 SER   A CA  1 
ATOM   3428 C C   . SER   A 1 426 ? 165.432 167.146 161.012 1.00 50.64  ? 452 SER   A C   1 
ATOM   3429 O O   . SER   A 1 426 ? 166.241 167.696 161.768 1.00 53.78  ? 452 SER   A O   1 
ATOM   3430 C CB  . SER   A 1 426 ? 164.390 168.439 159.141 1.00 47.85  ? 452 SER   A CB  1 
ATOM   3431 O OG  . SER   A 1 426 ? 164.512 169.615 159.918 1.00 53.70  ? 452 SER   A OG  1 
ATOM   3432 N N   . ARG   A 1 427 ? 164.509 166.293 161.461 1.00 52.67  ? 453 ARG   A N   1 
ATOM   3433 C CA  . ARG   A 1 427 ? 164.450 166.001 162.891 1.00 51.39  ? 453 ARG   A CA  1 
ATOM   3434 C C   . ARG   A 1 427 ? 165.543 165.040 163.347 1.00 51.08  ? 453 ARG   A C   1 
ATOM   3435 O O   . ARG   A 1 427 ? 165.898 165.060 164.529 1.00 50.89  ? 453 ARG   A O   1 
ATOM   3436 C CB  . ARG   A 1 427 ? 163.067 165.455 163.285 1.00 55.54  ? 453 ARG   A CB  1 
ATOM   3437 C CG  . ARG   A 1 427 ? 162.764 163.984 162.955 1.00 59.40  ? 453 ARG   A CG  1 
ATOM   3438 C CD  . ARG   A 1 427 ? 161.435 163.554 163.562 1.00 63.57  ? 453 ARG   A CD  1 
ATOM   3439 N NE  . ARG   A 1 427 ? 161.319 162.103 163.649 1.00 69.09  ? 453 ARG   A NE  1 
ATOM   3440 C CZ  . ARG   A 1 427 ? 160.305 161.456 164.211 1.00 78.25  ? 453 ARG   A CZ  1 
ATOM   3441 N NH1 . ARG   A 1 427 ? 159.282 162.099 164.754 1.00 78.71  ? 453 ARG   A NH1 1 
ATOM   3442 N NH2 . ARG   A 1 427 ? 160.317 160.126 164.229 1.00 77.08  ? 453 ARG   A NH2 1 
ATOM   3443 N N   . LEU   A 1 428 ? 166.088 164.211 162.451 1.00 51.41  ? 454 LEU   A N   1 
ATOM   3444 C CA  . LEU   A 1 428 ? 167.070 163.206 162.860 1.00 50.29  ? 454 LEU   A CA  1 
ATOM   3445 C C   . LEU   A 1 428 ? 168.512 163.701 162.797 1.00 52.53  ? 454 LEU   A C   1 
ATOM   3446 O O   . LEU   A 1 428 ? 169.322 163.335 163.655 1.00 57.17  ? 454 LEU   A O   1 
ATOM   3447 C CB  . LEU   A 1 428 ? 166.943 161.955 161.988 1.00 48.16  ? 454 LEU   A CB  1 
ATOM   3448 C CG  . LEU   A 1 428 ? 165.713 161.064 162.160 1.00 56.27  ? 454 LEU   A CG  1 
ATOM   3449 C CD1 . LEU   A 1 428 ? 165.722 159.958 161.120 1.00 55.86  ? 454 LEU   A CD1 1 
ATOM   3450 C CD2 . LEU   A 1 428 ? 165.648 160.471 163.557 1.00 59.88  ? 454 LEU   A CD2 1 
ATOM   3451 N N   . LEU   A 1 429 ? 168.855 164.510 161.796 1.00 51.42  ? 455 LEU   A N   1 
ATOM   3452 C CA  . LEU   A 1 429 ? 170.249 164.894 161.588 1.00 50.21  ? 455 LEU   A CA  1 
ATOM   3453 C C   . LEU   A 1 429 ? 170.896 165.631 162.757 1.00 52.65  ? 455 LEU   A C   1 
ATOM   3454 O O   . LEU   A 1 429 ? 172.109 165.447 162.957 1.00 59.33  ? 455 LEU   A O   1 
ATOM   3455 C CB  . LEU   A 1 429 ? 170.363 165.728 160.307 1.00 47.22  ? 455 LEU   A CB  1 
ATOM   3456 C CG  . LEU   A 1 429 ? 170.292 164.942 158.996 1.00 44.99  ? 455 LEU   A CG  1 
ATOM   3457 C CD1 . LEU   A 1 429 ? 170.163 165.893 157.824 1.00 49.53  ? 455 LEU   A CD1 1 
ATOM   3458 C CD2 . LEU   A 1 429 ? 171.506 164.053 158.817 1.00 43.23  ? 455 LEU   A CD2 1 
ATOM   3459 N N   . PRO   A 1 430 ? 170.202 166.475 163.530 1.00 48.16  ? 456 PRO   A N   1 
ATOM   3460 C CA  . PRO   A 1 430 ? 170.862 167.110 164.686 1.00 52.70  ? 456 PRO   A CA  1 
ATOM   3461 C C   . PRO   A 1 430 ? 171.458 166.142 165.692 1.00 56.36  ? 456 PRO   A C   1 
ATOM   3462 O O   . PRO   A 1 430 ? 172.290 166.560 166.507 1.00 57.12  ? 456 PRO   A O   1 
ATOM   3463 C CB  . PRO   A 1 430 ? 169.737 167.942 165.308 1.00 56.90  ? 456 PRO   A CB  1 
ATOM   3464 C CG  . PRO   A 1 430 ? 168.910 168.330 164.152 1.00 57.92  ? 456 PRO   A CG  1 
ATOM   3465 C CD  . PRO   A 1 430 ? 168.939 167.161 163.203 1.00 52.33  ? 456 PRO   A CD  1 
ATOM   3466 N N   . LYS   A 1 431 ? 171.073 164.871 165.666 1.00 56.86  ? 457 LYS   A N   1 
ATOM   3467 C CA  . LYS   A 1 431 ? 171.765 163.861 166.449 1.00 56.22  ? 457 LYS   A CA  1 
ATOM   3468 C C   . LYS   A 1 431 ? 173.176 163.585 165.939 1.00 59.57  ? 457 LYS   A C   1 
ATOM   3469 O O   . LYS   A 1 431 ? 173.946 162.927 166.646 1.00 64.82  ? 457 LYS   A O   1 
ATOM   3470 C CB  . LYS   A 1 431 ? 170.938 162.576 166.447 1.00 58.83  ? 457 LYS   A CB  1 
ATOM   3471 C CG  . LYS   A 1 431 ? 171.389 161.525 167.440 1.00 62.04  ? 457 LYS   A CG  1 
ATOM   3472 C CD  . LYS   A 1 431 ? 170.308 160.469 167.676 1.00 64.96  ? 457 LYS   A CD  1 
ATOM   3473 C CE  . LYS   A 1 431 ? 169.961 159.692 166.407 1.00 64.97  ? 457 LYS   A CE  1 
ATOM   3474 N NZ  . LYS   A 1 431 ? 168.983 158.600 166.667 1.00 64.54  ? 457 LYS   A NZ  1 
ATOM   3475 N N   . TYR   A 1 432 ? 173.532 164.070 164.742 1.00 58.94  ? 458 TYR   A N   1 
ATOM   3476 C CA  . TYR   A 1 432 ? 174.833 163.839 164.123 1.00 57.57  ? 458 TYR   A CA  1 
ATOM   3477 C C   . TYR   A 1 432 ? 175.616 165.137 163.917 1.00 61.73  ? 458 TYR   A C   1 
ATOM   3478 O O   . TYR   A 1 432 ? 176.368 165.264 162.949 1.00 61.16  ? 458 TYR   A O   1 
ATOM   3479 C CB  . TYR   A 1 432 ? 174.655 163.117 162.790 1.00 52.57  ? 458 TYR   A CB  1 
ATOM   3480 C CG  . TYR   A 1 432 ? 173.945 161.787 162.891 1.00 50.25  ? 458 TYR   A CG  1 
ATOM   3481 C CD1 . TYR   A 1 432 ? 172.561 161.714 162.883 1.00 51.82  ? 458 TYR   A CD1 1 
ATOM   3482 C CD2 . TYR   A 1 432 ? 174.659 160.603 162.977 1.00 54.97  ? 458 TYR   A CD2 1 
ATOM   3483 C CE1 . TYR   A 1 432 ? 171.912 160.503 162.970 1.00 54.96  ? 458 TYR   A CE1 1 
ATOM   3484 C CE2 . TYR   A 1 432 ? 174.017 159.389 163.062 1.00 55.62  ? 458 TYR   A CE2 1 
ATOM   3485 C CZ  . TYR   A 1 432 ? 172.644 159.345 163.059 1.00 57.23  ? 458 TYR   A CZ  1 
ATOM   3486 O OH  . TYR   A 1 432 ? 172.001 158.134 163.145 1.00 60.32  ? 458 TYR   A OH  1 
ATOM   3487 N N   . ASN   A 1 433 ? 175.452 166.106 164.819 1.00 63.23  ? 459 ASN   A N   1 
ATOM   3488 C CA  . ASN   A 1 433 ? 176.171 167.385 164.761 1.00 62.39  ? 459 ASN   A CA  1 
ATOM   3489 C C   . ASN   A 1 433 ? 175.889 168.139 163.460 1.00 64.74  ? 459 ASN   A C   1 
ATOM   3490 O O   . ASN   A 1 433 ? 176.807 168.585 162.768 1.00 67.44  ? 459 ASN   A O   1 
ATOM   3491 C CB  . ASN   A 1 433 ? 177.678 167.186 164.961 1.00 69.48  ? 459 ASN   A CB  1 
ATOM   3492 C CG  . ASN   A 1 433 ? 178.035 166.843 166.395 1.00 91.74  ? 459 ASN   A CG  1 
ATOM   3493 O OD1 . ASN   A 1 433 ? 177.451 167.379 167.336 1.00 94.81  ? 459 ASN   A OD1 1 
ATOM   3494 N ND2 . ASN   A 1 433 ? 179.005 165.950 166.569 1.00 108.67 ? 459 ASN   A ND2 1 
ATOM   3495 N N   . VAL   A 1 434 ? 174.608 168.276 163.119 1.00 62.19  ? 460 VAL   A N   1 
ATOM   3496 C CA  . VAL   A 1 434 ? 174.153 169.117 162.015 1.00 58.09  ? 460 VAL   A CA  1 
ATOM   3497 C C   . VAL   A 1 434 ? 173.103 170.078 162.554 1.00 60.41  ? 460 VAL   A C   1 
ATOM   3498 O O   . VAL   A 1 434 ? 172.115 169.648 163.156 1.00 65.58  ? 460 VAL   A O   1 
ATOM   3499 C CB  . VAL   A 1 434 ? 173.579 168.279 160.856 1.00 53.62  ? 460 VAL   A CB  1 
ATOM   3500 C CG1 . VAL   A 1 434 ? 173.001 169.183 159.784 1.00 55.90  ? 460 VAL   A CG1 1 
ATOM   3501 C CG2 . VAL   A 1 434 ? 174.644 167.374 160.268 1.00 54.47  ? 460 VAL   A CG2 1 
ATOM   3502 N N   . THR   A 1 435 ? 173.292 171.370 162.314 1.00 63.21  ? 461 THR   A N   1 
ATOM   3503 C CA  . THR   A 1 435 ? 172.320 172.365 162.751 1.00 64.62  ? 461 THR   A CA  1 
ATOM   3504 C C   . THR   A 1 435 ? 171.149 172.347 161.770 1.00 60.69  ? 461 THR   A C   1 
ATOM   3505 O O   . THR   A 1 435 ? 171.003 171.412 160.980 1.00 61.55  ? 461 THR   A O   1 
ATOM   3506 C CB  . THR   A 1 435 ? 172.974 173.739 162.879 1.00 72.84  ? 461 THR   A CB  1 
ATOM   3507 O OG1 . THR   A 1 435 ? 173.457 174.172 161.601 1.00 76.40  ? 461 THR   A OG1 1 
ATOM   3508 C CG2 . THR   A 1 435 ? 174.128 173.682 163.867 1.00 72.98  ? 461 THR   A CG2 1 
ATOM   3509 N N   . GLU   A 1 436 ? 170.277 173.363 161.833 1.00 59.54  ? 462 GLU   A N   1 
ATOM   3510 C CA  . GLU   A 1 436 ? 169.059 173.398 161.029 1.00 62.17  ? 462 GLU   A CA  1 
ATOM   3511 C C   . GLU   A 1 436 ? 169.400 173.255 159.547 1.00 60.83  ? 462 GLU   A C   1 
ATOM   3512 O O   . GLU   A 1 436 ? 169.902 174.212 158.945 1.00 63.86  ? 462 GLU   A O   1 
ATOM   3513 C CB  . GLU   A 1 436 ? 168.307 174.709 161.262 1.00 67.29  ? 462 GLU   A CB  1 
ATOM   3514 C CG  . GLU   A 1 436 ? 167.811 174.886 162.685 1.00 72.54  ? 462 GLU   A CG  1 
ATOM   3515 C CD  . GLU   A 1 436 ? 167.095 176.205 162.896 1.00 80.22  ? 462 GLU   A CD  1 
ATOM   3516 O OE1 . GLU   A 1 436 ? 167.029 177.007 161.941 1.00 78.60  ? 462 GLU   A OE1 1 
ATOM   3517 O OE2 . GLU   A 1 436 ? 166.598 176.440 164.017 1.00 82.72  ? 462 GLU   A OE2 1 
ATOM   3518 N N   . PRO   A 1 437 ? 169.147 172.106 158.916 1.00 53.52  ? 463 PRO   A N   1 
ATOM   3519 C CA  . PRO   A 1 437 ? 169.686 171.876 157.577 1.00 52.56  ? 463 PRO   A CA  1 
ATOM   3520 C C   . PRO   A 1 437 ? 168.736 172.306 156.469 1.00 51.76  ? 463 PRO   A C   1 
ATOM   3521 O O   . PRO   A 1 437 ? 167.541 172.521 156.675 1.00 50.13  ? 463 PRO   A O   1 
ATOM   3522 C CB  . PRO   A 1 437 ? 169.891 170.357 157.557 1.00 51.74  ? 463 PRO   A CB  1 
ATOM   3523 C CG  . PRO   A 1 437 ? 168.787 169.847 158.367 1.00 51.52  ? 463 PRO   A CG  1 
ATOM   3524 C CD  . PRO   A 1 437 ? 168.450 170.899 159.399 1.00 53.88  ? 463 PRO   A CD  1 
ATOM   3525 N N   . GLN   A 1 438 ? 169.311 172.433 155.277 1.00 51.53  ? 464 GLN   A N   1 
ATOM   3526 C CA  . GLN   A 1 438 ? 168.577 172.684 154.044 1.00 47.12  ? 464 GLN   A CA  1 
ATOM   3527 C C   . GLN   A 1 438 ? 168.890 171.545 153.087 1.00 42.64  ? 464 GLN   A C   1 
ATOM   3528 O O   . GLN   A 1 438 ? 170.027 171.432 152.620 1.00 49.02  ? 464 GLN   A O   1 
ATOM   3529 C CB  . GLN   A 1 438 ? 168.982 174.025 153.430 1.00 46.21  ? 464 GLN   A CB  1 
ATOM   3530 C CG  . GLN   A 1 438 ? 168.825 175.215 154.360 1.00 49.27  ? 464 GLN   A CG  1 
ATOM   3531 C CD  . GLN   A 1 438 ? 169.506 176.454 153.835 1.00 43.92  ? 464 GLN   A CD  1 
ATOM   3532 O OE1 . GLN   A 1 438 ? 170.012 176.472 152.718 1.00 41.95  ? 464 GLN   A OE1 1 
ATOM   3533 N NE2 . GLN   A 1 438 ? 169.527 177.501 154.646 1.00 40.84  ? 464 GLN   A NE2 1 
ATOM   3534 N N   . ILE   A 1 439 ? 167.885 170.735 152.761 1.00 38.09  ? 465 ILE   A N   1 
ATOM   3535 C CA  . ILE   A 1 439 ? 168.075 169.503 152.000 1.00 40.23  ? 465 ILE   A CA  1 
ATOM   3536 C C   . ILE   A 1 439 ? 167.607 169.741 150.570 1.00 46.35  ? 465 ILE   A C   1 
ATOM   3537 O O   . ILE   A 1 439 ? 166.504 170.256 150.345 1.00 49.97  ? 465 ILE   A O   1 
ATOM   3538 C CB  . ILE   A 1 439 ? 167.328 168.315 152.639 1.00 39.62  ? 465 ILE   A CB  1 
ATOM   3539 C CG1 . ILE   A 1 439 ? 167.709 168.176 154.120 1.00 45.86  ? 465 ILE   A CG1 1 
ATOM   3540 C CG2 . ILE   A 1 439 ? 167.656 166.998 151.909 1.00 43.14  ? 465 ILE   A CG2 1 
ATOM   3541 C CD1 . ILE   A 1 439 ? 167.019 167.037 154.847 1.00 51.01  ? 465 ILE   A CD1 1 
ATOM   3542 N N   . TYR   A 1 440 ? 168.451 169.365 149.609 1.00 40.83  ? 466 TYR   A N   1 
ATOM   3543 C CA  . TYR   A 1 440 ? 168.150 169.427 148.186 1.00 33.98  ? 466 TYR   A CA  1 
ATOM   3544 C C   . TYR   A 1 440 ? 168.214 168.022 147.607 1.00 36.54  ? 466 TYR   A C   1 
ATOM   3545 O O   . TYR   A 1 440 ? 169.065 167.220 148.002 1.00 44.53  ? 466 TYR   A O   1 
ATOM   3546 C CB  . TYR   A 1 440 ? 169.138 170.318 147.440 1.00 35.57  ? 466 TYR   A CB  1 
ATOM   3547 C CG  . TYR   A 1 440 ? 169.348 171.684 148.038 1.00 36.53  ? 466 TYR   A CG  1 
ATOM   3548 C CD1 . TYR   A 1 440 ? 168.562 172.756 147.660 1.00 42.35  ? 466 TYR   A CD1 1 
ATOM   3549 C CD2 . TYR   A 1 440 ? 170.352 171.907 148.959 1.00 38.26  ? 466 TYR   A CD2 1 
ATOM   3550 C CE1 . TYR   A 1 440 ? 168.760 174.006 148.197 1.00 42.30  ? 466 TYR   A CE1 1 
ATOM   3551 C CE2 . TYR   A 1 440 ? 170.559 173.153 149.498 1.00 40.26  ? 466 TYR   A CE2 1 
ATOM   3552 C CZ  . TYR   A 1 440 ? 169.761 174.199 149.114 1.00 39.12  ? 466 TYR   A CZ  1 
ATOM   3553 O OH  . TYR   A 1 440 ? 169.962 175.447 149.653 1.00 48.54  ? 466 TYR   A OH  1 
ATOM   3554 N N   . PHE   A 1 441 ? 167.321 167.731 146.664 1.00 36.56  ? 467 PHE   A N   1 
ATOM   3555 C CA  . PHE   A 1 441 ? 167.195 166.412 146.062 1.00 37.37  ? 467 PHE   A CA  1 
ATOM   3556 C C   . PHE   A 1 441 ? 167.401 166.494 144.557 1.00 45.09  ? 467 PHE   A C   1 
ATOM   3557 O O   . PHE   A 1 441 ? 167.007 167.470 143.912 1.00 51.60  ? 467 PHE   A O   1 
ATOM   3558 C CB  . PHE   A 1 441 ? 165.823 165.801 146.355 1.00 40.23  ? 467 PHE   A CB  1 
ATOM   3559 C CG  . PHE   A 1 441 ? 165.590 165.501 147.807 1.00 41.33  ? 467 PHE   A CG  1 
ATOM   3560 C CD1 . PHE   A 1 441 ? 165.178 166.491 148.677 1.00 42.77  ? 467 PHE   A CD1 1 
ATOM   3561 C CD2 . PHE   A 1 441 ? 165.769 164.225 148.296 1.00 38.81  ? 467 PHE   A CD2 1 
ATOM   3562 C CE1 . PHE   A 1 441 ? 164.959 166.212 150.007 1.00 41.88  ? 467 PHE   A CE1 1 
ATOM   3563 C CE2 . PHE   A 1 441 ? 165.555 163.943 149.623 1.00 35.13  ? 467 PHE   A CE2 1 
ATOM   3564 C CZ  . PHE   A 1 441 ? 165.149 164.936 150.478 1.00 36.24  ? 467 PHE   A CZ  1 
ATOM   3565 N N   . ASP   A 1 442 ? 168.022 165.455 144.001 1.00 45.85  ? 468 ASP   A N   1 
ATOM   3566 C CA  . ASP   A 1 442 ? 168.291 165.363 142.567 1.00 43.74  ? 468 ASP   A CA  1 
ATOM   3567 C C   . ASP   A 1 442 ? 168.118 163.909 142.153 1.00 39.43  ? 468 ASP   A C   1 
ATOM   3568 O O   . ASP   A 1 442 ? 168.975 163.076 142.461 1.00 43.12  ? 468 ASP   A O   1 
ATOM   3569 C CB  . ASP   A 1 442 ? 169.696 165.863 142.240 1.00 42.33  ? 468 ASP   A CB  1 
ATOM   3570 C CG  . ASP   A 1 442 ? 169.980 165.880 140.755 1.00 48.25  ? 468 ASP   A CG  1 
ATOM   3571 O OD1 . ASP   A 1 442 ? 169.037 165.679 139.960 1.00 49.85  ? 468 ASP   A OD1 1 
ATOM   3572 O OD2 . ASP   A 1 442 ? 171.149 166.098 140.377 1.00 49.47  ? 468 ASP   A OD2 1 
ATOM   3573 N N   . ILE   A 1 443 ? 167.023 163.608 141.456 1.00 34.46  ? 469 ILE   A N   1 
ATOM   3574 C CA  . ILE   A 1 443 ? 166.630 162.240 141.132 1.00 37.40  ? 469 ILE   A CA  1 
ATOM   3575 C C   . ILE   A 1 443 ? 166.441 162.132 139.626 1.00 40.75  ? 469 ILE   A C   1 
ATOM   3576 O O   . ILE   A 1 443 ? 165.729 162.946 139.032 1.00 43.71  ? 469 ILE   A O   1 
ATOM   3577 C CB  . ILE   A 1 443 ? 165.337 161.835 141.867 1.00 40.17  ? 469 ILE   A CB  1 
ATOM   3578 C CG1 . ILE   A 1 443 ? 165.558 161.820 143.385 1.00 44.64  ? 469 ILE   A CG1 1 
ATOM   3579 C CG2 . ILE   A 1 443 ? 164.862 160.472 141.387 1.00 43.43  ? 469 ILE   A CG2 1 
ATOM   3580 C CD1 . ILE   A 1 443 ? 164.286 161.883 144.195 1.00 45.76  ? 469 ILE   A CD1 1 
ATOM   3581 N N   . TRP   A 1 444 ? 167.054 161.116 139.019 1.00 37.02  ? 470 TRP   A N   1 
ATOM   3582 C CA  . TRP   A 1 444 ? 166.970 160.869 137.583 1.00 31.97  ? 470 TRP   A CA  1 
ATOM   3583 C C   . TRP   A 1 444 ? 166.233 159.564 137.336 1.00 34.81  ? 470 TRP   A C   1 
ATOM   3584 O O   . TRP   A 1 444 ? 166.673 158.505 137.799 1.00 42.34  ? 470 TRP   A O   1 
ATOM   3585 C CB  . TRP   A 1 444 ? 168.361 160.796 136.959 1.00 31.79  ? 470 TRP   A CB  1 
ATOM   3586 C CG  . TRP   A 1 444 ? 169.125 162.059 137.027 1.00 31.80  ? 470 TRP   A CG  1 
ATOM   3587 C CD1 . TRP   A 1 444 ? 169.853 162.516 138.078 1.00 36.89  ? 470 TRP   A CD1 1 
ATOM   3588 C CD2 . TRP   A 1 444 ? 169.256 163.034 135.994 1.00 32.25  ? 470 TRP   A CD2 1 
ATOM   3589 N NE1 . TRP   A 1 444 ? 170.427 163.720 137.768 1.00 39.26  ? 470 TRP   A NE1 1 
ATOM   3590 C CE2 . TRP   A 1 444 ? 170.073 164.060 136.491 1.00 34.32  ? 470 TRP   A CE2 1 
ATOM   3591 C CE3 . TRP   A 1 444 ? 168.756 163.142 134.696 1.00 38.85  ? 470 TRP   A CE3 1 
ATOM   3592 C CZ2 . TRP   A 1 444 ? 170.402 165.178 135.740 1.00 39.61  ? 470 TRP   A CZ2 1 
ATOM   3593 C CZ3 . TRP   A 1 444 ? 169.083 164.253 133.954 1.00 39.93  ? 470 TRP   A CZ3 1 
ATOM   3594 C CH2 . TRP   A 1 444 ? 169.899 165.256 134.476 1.00 40.83  ? 470 TRP   A CH2 1 
ATOM   3595 N N   . VAL   A 1 445 ? 165.144 159.633 136.569 1.00 32.24  ? 471 VAL   A N   1 
ATOM   3596 C CA  . VAL   A 1 445 ? 164.264 158.489 136.357 1.00 33.90  ? 471 VAL   A CA  1 
ATOM   3597 C C   . VAL   A 1 445 ? 163.696 158.562 134.949 1.00 33.75  ? 471 VAL   A C   1 
ATOM   3598 O O   . VAL   A 1 445 ? 163.422 159.645 134.426 1.00 38.56  ? 471 VAL   A O   1 
ATOM   3599 C CB  . VAL   A 1 445 ? 163.137 158.450 137.418 1.00 39.43  ? 471 VAL   A CB  1 
ATOM   3600 C CG1 . VAL   A 1 445 ? 162.494 159.816 137.576 1.00 41.35  ? 471 VAL   A CG1 1 
ATOM   3601 C CG2 . VAL   A 1 445 ? 162.091 157.398 137.077 1.00 41.76  ? 471 VAL   A CG2 1 
ATOM   3602 N N   . SER   A 1 446 ? 163.525 157.393 134.336 1.00 33.13  ? 472 SER   A N   1 
ATOM   3603 C CA  . SER   A 1 446 ? 162.905 157.257 133.027 1.00 37.55  ? 472 SER   A CA  1 
ATOM   3604 C C   . SER   A 1 446 ? 161.779 156.242 133.118 1.00 42.68  ? 472 SER   A C   1 
ATOM   3605 O O   . SER   A 1 446 ? 161.953 155.164 133.699 1.00 45.21  ? 472 SER   A O   1 
ATOM   3606 C CB  . SER   A 1 446 ? 163.915 156.808 131.975 1.00 41.35  ? 472 SER   A CB  1 
ATOM   3607 O OG  . SER   A 1 446 ? 164.284 155.456 132.177 1.00 42.47  ? 472 SER   A OG  1 
ATOM   3608 N N   . ILE   A 1 447 ? 160.634 156.593 132.530 1.00 41.53  ? 473 ILE   A N   1 
ATOM   3609 C CA  . ILE   A 1 447 ? 159.426 155.773 132.549 1.00 39.98  ? 473 ILE   A CA  1 
ATOM   3610 C C   . ILE   A 1 447 ? 159.218 155.217 131.148 1.00 45.89  ? 473 ILE   A C   1 
ATOM   3611 O O   . ILE   A 1 447 ? 159.154 155.978 130.176 1.00 50.31  ? 473 ILE   A O   1 
ATOM   3612 C CB  . ILE   A 1 447 ? 158.198 156.570 133.020 1.00 38.21  ? 473 ILE   A CB  1 
ATOM   3613 C CG1 . ILE   A 1 447 ? 158.408 157.006 134.476 1.00 45.15  ? 473 ILE   A CG1 1 
ATOM   3614 C CG2 . ILE   A 1 447 ? 156.907 155.731 132.839 1.00 44.46  ? 473 ILE   A CG2 1 
ATOM   3615 C CD1 . ILE   A 1 447 ? 157.263 157.784 135.110 1.00 48.08  ? 473 ILE   A CD1 1 
ATOM   3616 N N   . ASN   A 1 448 ? 159.093 153.893 131.053 1.00 49.16  ? 474 ASN   A N   1 
ATOM   3617 C CA  . ASN   A 1 448 ? 158.834 153.203 129.789 1.00 46.19  ? 474 ASN   A CA  1 
ATOM   3618 C C   . ASN   A 1 448 ? 159.904 153.534 128.751 1.00 49.54  ? 474 ASN   A C   1 
ATOM   3619 O O   . ASN   A 1 448 ? 159.613 153.803 127.584 1.00 51.63  ? 474 ASN   A O   1 
ATOM   3620 C CB  . ASN   A 1 448 ? 157.437 153.528 129.262 1.00 46.45  ? 474 ASN   A CB  1 
ATOM   3621 C CG  . ASN   A 1 448 ? 156.343 152.964 130.139 1.00 52.78  ? 474 ASN   A CG  1 
ATOM   3622 O OD1 . ASN   A 1 448 ? 156.500 151.901 130.736 1.00 52.36  ? 474 ASN   A OD1 1 
ATOM   3623 N ND2 . ASN   A 1 448 ? 155.223 153.670 130.218 1.00 56.52  ? 474 ASN   A ND2 1 
ATOM   3624 N N   . ASP   A 1 449 ? 161.158 153.508 129.193 1.00 49.19  ? 475 ASP   A N   1 
ATOM   3625 C CA  . ASP   A 1 449 ? 162.314 153.635 128.311 1.00 47.98  ? 475 ASP   A CA  1 
ATOM   3626 C C   . ASP   A 1 449 ? 162.296 154.968 127.559 1.00 45.60  ? 475 ASP   A C   1 
ATOM   3627 O O   . ASP   A 1 449 ? 162.276 155.017 126.331 1.00 48.86  ? 475 ASP   A O   1 
ATOM   3628 C CB  . ASP   A 1 449 ? 162.371 152.449 127.340 1.00 46.98  ? 475 ASP   A CB  1 
ATOM   3629 C CG  . ASP   A 1 449 ? 163.675 152.382 126.570 1.00 57.96  ? 475 ASP   A CG  1 
ATOM   3630 O OD1 . ASP   A 1 449 ? 164.579 153.202 126.838 1.00 57.50  ? 475 ASP   A OD1 1 
ATOM   3631 O OD2 . ASP   A 1 449 ? 163.799 151.503 125.691 1.00 64.99  ? 475 ASP   A OD2 1 
ATOM   3632 N N   . ARG   A 1 450 ? 162.301 156.052 128.328 1.00 42.75  ? 476 ARG   A N   1 
ATOM   3633 C CA  . ARG   A 1 450 ? 162.469 157.409 127.825 1.00 40.95  ? 476 ARG   A CA  1 
ATOM   3634 C C   . ARG   A 1 450 ? 163.844 157.929 128.237 1.00 40.83  ? 476 ARG   A C   1 
ATOM   3635 O O   . ARG   A 1 450 ? 164.644 157.220 128.852 1.00 41.63  ? 476 ARG   A O   1 
ATOM   3636 C CB  . ARG   A 1 450 ? 161.355 158.320 128.350 1.00 40.84  ? 476 ARG   A CB  1 
ATOM   3637 C CG  . ARG   A 1 450 ? 159.973 157.982 127.838 1.00 44.16  ? 476 ARG   A CG  1 
ATOM   3638 C CD  . ARG   A 1 450 ? 158.915 158.827 128.523 1.00 45.14  ? 476 ARG   A CD  1 
ATOM   3639 N NE  . ARG   A 1 450 ? 157.583 158.250 128.387 1.00 45.86  ? 476 ARG   A NE  1 
ATOM   3640 C CZ  . ARG   A 1 450 ? 156.748 158.467 127.380 1.00 51.14  ? 476 ARG   A CZ  1 
ATOM   3641 N NH1 . ARG   A 1 450 ? 157.060 159.265 126.371 1.00 51.75  ? 476 ARG   A NH1 1 
ATOM   3642 N NH2 . ARG   A 1 450 ? 155.565 157.860 127.381 1.00 54.95  ? 476 ARG   A NH2 1 
ATOM   3643 N N   . PHE   A 1 451 ? 164.119 159.182 127.887 1.00 43.55  ? 477 PHE   A N   1 
ATOM   3644 C CA  . PHE   A 1 451 ? 165.336 159.829 128.353 1.00 41.50  ? 477 PHE   A CA  1 
ATOM   3645 C C   . PHE   A 1 451 ? 165.303 159.975 129.867 1.00 40.39  ? 477 PHE   A C   1 
ATOM   3646 O O   . PHE   A 1 451 ? 164.253 160.237 130.459 1.00 41.12  ? 477 PHE   A O   1 
ATOM   3647 C CB  . PHE   A 1 451 ? 165.488 161.210 127.719 1.00 38.78  ? 477 PHE   A CB  1 
ATOM   3648 C CG  . PHE   A 1 451 ? 165.815 161.186 126.261 1.00 37.56  ? 477 PHE   A CG  1 
ATOM   3649 C CD1 . PHE   A 1 451 ? 164.814 161.179 125.315 1.00 43.06  ? 477 PHE   A CD1 1 
ATOM   3650 C CD2 . PHE   A 1 451 ? 167.126 161.207 125.836 1.00 39.71  ? 477 PHE   A CD2 1 
ATOM   3651 C CE1 . PHE   A 1 451 ? 165.117 161.174 123.977 1.00 48.14  ? 477 PHE   A CE1 1 
ATOM   3652 C CE2 . PHE   A 1 451 ? 167.434 161.205 124.501 1.00 41.78  ? 477 PHE   A CE2 1 
ATOM   3653 C CZ  . PHE   A 1 451 ? 166.431 161.189 123.569 1.00 46.71  ? 477 PHE   A CZ  1 
ATOM   3654 N N   . GLN   A 1 452 ? 166.459 159.803 130.497 1.00 36.81  ? 478 GLN   A N   1 
ATOM   3655 C CA  . GLN   A 1 452 ? 166.576 160.075 131.921 1.00 32.81  ? 478 GLN   A CA  1 
ATOM   3656 C C   . GLN   A 1 452 ? 166.505 161.579 132.140 1.00 34.80  ? 478 GLN   A C   1 
ATOM   3657 O O   . GLN   A 1 452 ? 167.254 162.335 131.513 1.00 42.45  ? 478 GLN   A O   1 
ATOM   3658 C CB  . GLN   A 1 452 ? 167.887 159.519 132.468 1.00 33.95  ? 478 GLN   A CB  1 
ATOM   3659 C CG  . GLN   A 1 452 ? 168.054 158.011 132.363 1.00 34.38  ? 478 GLN   A CG  1 
ATOM   3660 C CD  . GLN   A 1 452 ? 167.340 157.263 133.466 1.00 36.82  ? 478 GLN   A CD  1 
ATOM   3661 O OE1 . GLN   A 1 452 ? 166.571 157.842 134.231 1.00 41.72  ? 478 GLN   A OE1 1 
ATOM   3662 N NE2 . GLN   A 1 452 ? 167.595 155.967 133.558 1.00 36.26  ? 478 GLN   A NE2 1 
ATOM   3663 N N   . GLN   A 1 453 ? 165.607 162.016 133.017 1.00 32.76  ? 479 GLN   A N   1 
ATOM   3664 C CA  . GLN   A 1 453 ? 165.444 163.431 133.311 1.00 35.47  ? 479 GLN   A CA  1 
ATOM   3665 C C   . GLN   A 1 453 ? 165.163 163.621 134.792 1.00 38.85  ? 479 GLN   A C   1 
ATOM   3666 O O   . GLN   A 1 453 ? 164.722 162.703 135.486 1.00 40.64  ? 479 GLN   A O   1 
ATOM   3667 C CB  . GLN   A 1 453 ? 164.312 164.048 132.491 1.00 42.25  ? 479 GLN   A CB  1 
ATOM   3668 C CG  . GLN   A 1 453 ? 163.019 163.251 132.544 1.00 40.84  ? 479 GLN   A CG  1 
ATOM   3669 C CD  . GLN   A 1 453 ? 161.825 164.035 132.064 1.00 41.32  ? 479 GLN   A CD  1 
ATOM   3670 O OE1 . GLN   A 1 453 ? 161.858 165.259 131.992 1.00 38.36  ? 479 GLN   A OE1 1 
ATOM   3671 N NE2 . GLN   A 1 453 ? 160.755 163.329 131.737 1.00 47.36  ? 479 GLN   A NE2 1 
ATOM   3672 N N   . ARG   A 1 454 ? 165.419 164.836 135.265 1.00 38.85  ? 480 ARG   A N   1 
ATOM   3673 C CA  . ARG   A 1 454 ? 165.079 165.185 136.634 1.00 36.74  ? 480 ARG   A CA  1 
ATOM   3674 C C   . ARG   A 1 454 ? 163.568 165.158 136.825 1.00 41.74  ? 480 ARG   A C   1 
ATOM   3675 O O   . ARG   A 1 454 ? 162.800 165.479 135.914 1.00 48.78  ? 480 ARG   A O   1 
ATOM   3676 C CB  . ARG   A 1 454 ? 165.621 166.568 136.982 1.00 39.12  ? 480 ARG   A CB  1 
ATOM   3677 C CG  . ARG   A 1 454 ? 167.129 166.650 137.086 1.00 41.37  ? 480 ARG   A CG  1 
ATOM   3678 C CD  . ARG   A 1 454 ? 167.561 168.084 137.308 1.00 46.67  ? 480 ARG   A CD  1 
ATOM   3679 N NE  . ARG   A 1 454 ? 168.962 168.208 137.698 1.00 48.17  ? 480 ARG   A NE  1 
ATOM   3680 C CZ  . ARG   A 1 454 ? 169.987 168.333 136.865 1.00 48.62  ? 480 ARG   A CZ  1 
ATOM   3681 N NH1 . ARG   A 1 454 ? 169.828 168.323 135.550 1.00 49.50  ? 480 ARG   A NH1 1 
ATOM   3682 N NH2 . ARG   A 1 454 ? 171.211 168.472 137.365 1.00 45.25  ? 480 ARG   A NH2 1 
ATOM   3683 N N   . ILE   A 1 455 ? 163.147 164.768 138.028 1.00 39.70  ? 481 ILE   A N   1 
ATOM   3684 C CA  . ILE   A 1 455 ? 161.732 164.730 138.391 1.00 39.79  ? 481 ILE   A CA  1 
ATOM   3685 C C   . ILE   A 1 455 ? 161.416 165.887 139.330 1.00 41.10  ? 481 ILE   A C   1 
ATOM   3686 O O   . ILE   A 1 455 ? 160.308 166.434 139.296 1.00 46.78  ? 481 ILE   A O   1 
ATOM   3687 C CB  . ILE   A 1 455 ? 161.333 163.375 139.012 1.00 40.71  ? 481 ILE   A CB  1 
ATOM   3688 C CG1 . ILE   A 1 455 ? 159.908 163.440 139.565 1.00 43.34  ? 481 ILE   A CG1 1 
ATOM   3689 C CG2 . ILE   A 1 455 ? 162.321 162.930 140.095 1.00 42.41  ? 481 ILE   A CG2 1 
ATOM   3690 C CD1 . ILE   A 1 455 ? 159.247 162.084 139.721 1.00 47.99  ? 481 ILE   A CD1 1 
ATOM   3691 N N   . PHE   A 1 456 ? 162.381 166.272 140.164 1.00 39.37  ? 482 PHE   A N   1 
ATOM   3692 C CA  . PHE   A 1 456 ? 162.218 167.342 141.136 1.00 38.82  ? 482 PHE   A CA  1 
ATOM   3693 C C   . PHE   A 1 456 ? 163.246 168.436 140.887 1.00 42.99  ? 482 PHE   A C   1 
ATOM   3694 O O   . PHE   A 1 456 ? 164.370 168.169 140.455 1.00 50.96  ? 482 PHE   A O   1 
ATOM   3695 C CB  . PHE   A 1 456 ? 162.357 166.814 142.567 1.00 39.15  ? 482 PHE   A CB  1 
ATOM   3696 C CG  . PHE   A 1 456 ? 161.248 165.896 142.980 1.00 38.90  ? 482 PHE   A CG  1 
ATOM   3697 C CD1 . PHE   A 1 456 ? 160.003 166.397 143.302 1.00 41.13  ? 482 PHE   A CD1 1 
ATOM   3698 C CD2 . PHE   A 1 456 ? 161.451 164.533 143.053 1.00 42.44  ? 482 PHE   A CD2 1 
ATOM   3699 C CE1 . PHE   A 1 456 ? 158.983 165.556 143.679 1.00 43.58  ? 482 PHE   A CE1 1 
ATOM   3700 C CE2 . PHE   A 1 456 ? 160.432 163.687 143.425 1.00 44.85  ? 482 PHE   A CE2 1 
ATOM   3701 C CZ  . PHE   A 1 456 ? 159.199 164.199 143.742 1.00 47.18  ? 482 PHE   A CZ  1 
ATOM   3702 N N   . ASP   A 1 457 ? 162.844 169.667 141.160 1.00 41.47  ? 483 ASP   A N   1 
ATOM   3703 C CA  . ASP   A 1 457 ? 163.716 170.820 140.976 1.00 43.37  ? 483 ASP   A CA  1 
ATOM   3704 C C   . ASP   A 1 457 ? 164.884 170.734 141.957 1.00 49.15  ? 483 ASP   A C   1 
ATOM   3705 O O   . ASP   A 1 457 ? 164.643 170.688 143.171 1.00 54.03  ? 483 ASP   A O   1 
ATOM   3706 C CB  . ASP   A 1 457 ? 162.912 172.095 141.204 1.00 42.77  ? 483 ASP   A CB  1 
ATOM   3707 C CG  . ASP   A 1 457 ? 163.633 173.338 140.741 1.00 47.64  ? 483 ASP   A CG  1 
ATOM   3708 O OD1 . ASP   A 1 457 ? 164.791 173.236 140.291 1.00 52.96  ? 483 ASP   A OD1 1 
ATOM   3709 O OD2 . ASP   A 1 457 ? 163.034 174.428 140.823 1.00 50.69  ? 483 ASP   A OD2 1 
ATOM   3710 N N   . PRO   A 1 458 ? 166.144 170.710 141.511 1.00 45.36  ? 484 PRO   A N   1 
ATOM   3711 C CA  . PRO   A 1 458 ? 167.255 170.530 142.452 1.00 42.67  ? 484 PRO   A CA  1 
ATOM   3712 C C   . PRO   A 1 458 ? 167.722 171.797 143.150 1.00 45.31  ? 484 PRO   A C   1 
ATOM   3713 O O   . PRO   A 1 458 ? 168.767 171.760 143.805 1.00 49.20  ? 484 PRO   A O   1 
ATOM   3714 C CB  . PRO   A 1 458 ? 168.362 169.970 141.549 1.00 45.23  ? 484 PRO   A CB  1 
ATOM   3715 C CG  . PRO   A 1 458 ? 168.117 170.605 140.263 1.00 48.43  ? 484 PRO   A CG  1 
ATOM   3716 C CD  . PRO   A 1 458 ? 166.633 170.672 140.119 1.00 47.71  ? 484 PRO   A CD  1 
ATOM   3717 N N   . ARG   A 1 459 ? 166.987 172.901 143.041 1.00 48.32  ? 485 ARG   A N   1 
ATOM   3718 C CA  . ARG   A 1 459 ? 167.334 174.160 143.687 1.00 48.21  ? 485 ARG   A CA  1 
ATOM   3719 C C   . ARG   A 1 459 ? 166.362 174.536 144.796 1.00 48.10  ? 485 ARG   A C   1 
ATOM   3720 O O   . ARG   A 1 459 ? 166.423 175.662 145.299 1.00 48.89  ? 485 ARG   A O   1 
ATOM   3721 C CB  . ARG   A 1 459 ? 167.378 175.286 142.655 1.00 51.70  ? 485 ARG   A CB  1 
ATOM   3722 C CG  . ARG   A 1 459 ? 168.400 175.099 141.548 1.00 53.92  ? 485 ARG   A CG  1 
ATOM   3723 C CD  . ARG   A 1 459 ? 168.177 176.104 140.432 1.00 53.33  ? 485 ARG   A CD  1 
ATOM   3724 N NE  . ARG   A 1 459 ? 166.930 175.850 139.720 1.00 50.41  ? 485 ARG   A NE  1 
ATOM   3725 C CZ  . ARG   A 1 459 ? 166.439 176.608 138.750 1.00 51.74  ? 485 ARG   A CZ  1 
ATOM   3726 N NH1 . ARG   A 1 459 ? 167.054 177.709 138.349 1.00 52.42  ? 485 ARG   A NH1 1 
ATOM   3727 N NH2 . ARG   A 1 459 ? 165.300 176.252 138.166 1.00 50.61  ? 485 ARG   A NH2 1 
ATOM   3728 N N   . VAL   A 1 460 ? 165.477 173.625 145.194 1.00 46.33  ? 486 VAL   A N   1 
ATOM   3729 C CA  . VAL   A 1 460 ? 164.397 173.910 146.130 1.00 45.09  ? 486 VAL   A CA  1 
ATOM   3730 C C   . VAL   A 1 460 ? 164.671 173.139 147.412 1.00 47.60  ? 486 VAL   A C   1 
ATOM   3731 O O   . VAL   A 1 460 ? 164.844 171.914 147.384 1.00 49.96  ? 486 VAL   A O   1 
ATOM   3732 C CB  . VAL   A 1 460 ? 163.028 173.533 145.543 1.00 47.29  ? 486 VAL   A CB  1 
ATOM   3733 C CG1 . VAL   A 1 460 ? 161.918 173.835 146.544 1.00 48.58  ? 486 VAL   A CG1 1 
ATOM   3734 C CG2 . VAL   A 1 460 ? 162.789 174.271 144.230 1.00 47.80  ? 486 VAL   A CG2 1 
ATOM   3735 N N   . ASP   A 1 461 ? 164.718 173.854 148.530 1.00 44.92  ? 487 ASP   A N   1 
ATOM   3736 C CA  . ASP   A 1 461 ? 164.842 173.227 149.840 1.00 41.93  ? 487 ASP   A CA  1 
ATOM   3737 C C   . ASP   A 1 461 ? 163.510 172.590 150.207 1.00 46.88  ? 487 ASP   A C   1 
ATOM   3738 O O   . ASP   A 1 461 ? 162.546 173.292 150.529 1.00 51.85  ? 487 ASP   A O   1 
ATOM   3739 C CB  . ASP   A 1 461 ? 165.258 174.263 150.878 1.00 42.46  ? 487 ASP   A CB  1 
ATOM   3740 C CG  . ASP   A 1 461 ? 165.481 173.660 152.245 1.00 48.24  ? 487 ASP   A CG  1 
ATOM   3741 O OD1 . ASP   A 1 461 ? 165.577 172.419 152.345 1.00 52.74  ? 487 ASP   A OD1 1 
ATOM   3742 O OD2 . ASP   A 1 461 ? 165.559 174.427 153.225 1.00 49.82  ? 487 ASP   A OD2 1 
ATOM   3743 N N   . ILE   A 1 462 ? 163.445 171.258 150.159 1.00 40.31  ? 488 ILE   A N   1 
ATOM   3744 C CA  . ILE   A 1 462 ? 162.176 170.579 150.381 1.00 37.94  ? 488 ILE   A CA  1 
ATOM   3745 C C   . ILE   A 1 462 ? 161.717 170.696 151.830 1.00 44.11  ? 488 ILE   A C   1 
ATOM   3746 O O   . ILE   A 1 462 ? 160.529 170.514 152.113 1.00 48.13  ? 488 ILE   A O   1 
ATOM   3747 C CB  . ILE   A 1 462 ? 162.280 169.100 149.956 1.00 37.85  ? 488 ILE   A CB  1 
ATOM   3748 C CG1 . ILE   A 1 462 ? 162.796 168.966 148.513 1.00 40.63  ? 488 ILE   A CG1 1 
ATOM   3749 C CG2 . ILE   A 1 462 ? 160.934 168.399 150.108 1.00 44.75  ? 488 ILE   A CG2 1 
ATOM   3750 C CD1 . ILE   A 1 462 ? 161.982 169.696 147.456 1.00 45.34  ? 488 ILE   A CD1 1 
ATOM   3751 N N   . VAL   A 1 463 ? 162.622 171.011 152.759 1.00 43.07  ? 489 VAL   A N   1 
ATOM   3752 C CA  . VAL   A 1 463 ? 162.236 171.121 154.161 1.00 39.98  ? 489 VAL   A CA  1 
ATOM   3753 C C   . VAL   A 1 463 ? 161.300 172.305 154.373 1.00 43.52  ? 489 VAL   A C   1 
ATOM   3754 O O   . VAL   A 1 463 ? 160.363 172.230 155.176 1.00 46.56  ? 489 VAL   A O   1 
ATOM   3755 C CB  . VAL   A 1 463 ? 163.490 171.222 155.049 1.00 43.30  ? 489 VAL   A CB  1 
ATOM   3756 C CG1 . VAL   A 1 463 ? 163.105 171.519 156.489 1.00 47.73  ? 489 VAL   A CG1 1 
ATOM   3757 C CG2 . VAL   A 1 463 ? 164.304 169.938 154.967 1.00 46.13  ? 489 VAL   A CG2 1 
ATOM   3758 N N   . GLN   A 1 464 ? 161.536 173.410 153.667 1.00 45.63  ? 490 GLN   A N   1 
ATOM   3759 C CA  . GLN   A 1 464 ? 160.726 174.618 153.780 1.00 45.69  ? 490 GLN   A CA  1 
ATOM   3760 C C   . GLN   A 1 464 ? 159.743 174.799 152.629 1.00 47.69  ? 490 GLN   A C   1 
ATOM   3761 O O   . GLN   A 1 464 ? 159.020 175.798 152.609 1.00 52.82  ? 490 GLN   A O   1 
ATOM   3762 C CB  . GLN   A 1 464 ? 161.630 175.851 153.864 1.00 45.01  ? 490 GLN   A CB  1 
ATOM   3763 C CG  . GLN   A 1 464 ? 162.511 175.908 155.098 1.00 48.97  ? 490 GLN   A CG  1 
ATOM   3764 C CD  . GLN   A 1 464 ? 161.729 176.181 156.362 1.00 54.73  ? 490 GLN   A CD  1 
ATOM   3765 O OE1 . GLN   A 1 464 ? 160.520 176.394 156.323 1.00 55.19  ? 490 GLN   A OE1 1 
ATOM   3766 N NE2 . GLN   A 1 464 ? 162.419 176.182 157.495 1.00 55.92  ? 490 GLN   A NE2 1 
ATOM   3767 N N   . ALA   A 1 465 ? 159.690 173.870 151.678 1.00 44.23  ? 491 ALA   A N   1 
ATOM   3768 C CA  . ALA   A 1 465 ? 158.814 174.030 150.529 1.00 42.51  ? 491 ALA   A CA  1 
ATOM   3769 C C   . ALA   A 1 465 ? 157.356 173.826 150.938 1.00 44.93  ? 491 ALA   A C   1 
ATOM   3770 O O   . ALA   A 1 465 ? 157.046 173.308 152.014 1.00 48.84  ? 491 ALA   A O   1 
ATOM   3771 C CB  . ALA   A 1 465 ? 159.199 173.054 149.421 1.00 42.62  ? 491 ALA   A CB  1 
ATOM   3772 N N   . ALA   A 1 466 ? 156.453 174.241 150.053 1.00 42.27  ? 492 ALA   A N   1 
ATOM   3773 C CA  . ALA   A 1 466 ? 155.021 174.241 150.320 1.00 45.95  ? 492 ALA   A CA  1 
ATOM   3774 C C   . ALA   A 1 466 ? 154.362 173.056 149.627 1.00 47.72  ? 492 ALA   A C   1 
ATOM   3775 O O   . ALA   A 1 466 ? 154.622 172.797 148.448 1.00 48.75  ? 492 ALA   A O   1 
ATOM   3776 C CB  . ALA   A 1 466 ? 154.386 175.546 149.843 1.00 48.30  ? 492 ALA   A CB  1 
ATOM   3777 N N   . TRP   A 1 467 ? 153.514 172.342 150.364 1.00 44.38  ? 493 TRP   A N   1 
ATOM   3778 C CA  . TRP   A 1 467 ? 152.766 171.209 149.836 1.00 38.74  ? 493 TRP   A CA  1 
ATOM   3779 C C   . TRP   A 1 467 ? 151.419 171.140 150.535 1.00 45.19  ? 493 TRP   A C   1 
ATOM   3780 O O   . TRP   A 1 467 ? 151.362 171.142 151.768 1.00 52.30  ? 493 TRP   A O   1 
ATOM   3781 C CB  . TRP   A 1 467 ? 153.528 169.896 150.042 1.00 37.74  ? 493 TRP   A CB  1 
ATOM   3782 C CG  . TRP   A 1 467 ? 152.751 168.673 149.667 1.00 39.07  ? 493 TRP   A CG  1 
ATOM   3783 C CD1 . TRP   A 1 467 ? 152.705 168.079 148.448 1.00 43.49  ? 493 TRP   A CD1 1 
ATOM   3784 C CD2 . TRP   A 1 467 ? 151.917 167.890 150.526 1.00 42.77  ? 493 TRP   A CD2 1 
ATOM   3785 N NE1 . TRP   A 1 467 ? 151.892 166.976 148.486 1.00 38.93  ? 493 TRP   A NE1 1 
ATOM   3786 C CE2 . TRP   A 1 467 ? 151.393 166.839 149.754 1.00 40.19  ? 493 TRP   A CE2 1 
ATOM   3787 C CE3 . TRP   A 1 467 ? 151.559 167.979 151.875 1.00 50.79  ? 493 TRP   A CE3 1 
ATOM   3788 C CZ2 . TRP   A 1 467 ? 150.532 165.884 150.281 1.00 46.69  ? 493 TRP   A CZ2 1 
ATOM   3789 C CZ3 . TRP   A 1 467 ? 150.704 167.030 152.397 1.00 52.03  ? 493 TRP   A CZ3 1 
ATOM   3790 C CH2 . TRP   A 1 467 ? 150.200 165.996 151.602 1.00 49.89  ? 493 TRP   A CH2 1 
ATOM   3791 N N   . SER   A 1 468 ? 150.344 171.091 149.749 1.00 45.24  ? 494 SER   A N   1 
ATOM   3792 C CA  . SER   A 1 468 ? 149.009 170.811 150.253 1.00 44.78  ? 494 SER   A CA  1 
ATOM   3793 C C   . SER   A 1 468 ? 148.352 169.773 149.352 1.00 45.29  ? 494 SER   A C   1 
ATOM   3794 O O   . SER   A 1 468 ? 148.642 169.744 148.150 1.00 50.01  ? 494 SER   A O   1 
ATOM   3795 C CB  . SER   A 1 468 ? 148.153 172.081 150.303 1.00 47.96  ? 494 SER   A CB  1 
ATOM   3796 O OG  . SER   A 1 468 ? 148.080 172.694 149.030 1.00 55.36  ? 494 SER   A OG  1 
ATOM   3797 N N   . PRO   A 1 469 ? 147.488 168.898 149.881 1.00 41.35  ? 495 PRO   A N   1 
ATOM   3798 C CA  . PRO   A 1 469 ? 146.926 167.845 149.019 1.00 40.01  ? 495 PRO   A CA  1 
ATOM   3799 C C   . PRO   A 1 469 ? 146.080 168.366 147.873 1.00 47.00  ? 495 PRO   A C   1 
ATOM   3800 O O   . PRO   A 1 469 ? 146.008 167.708 146.829 1.00 51.47  ? 495 PRO   A O   1 
ATOM   3801 C CB  . PRO   A 1 469 ? 146.080 167.008 149.987 1.00 43.68  ? 495 PRO   A CB  1 
ATOM   3802 C CG  . PRO   A 1 469 ? 146.580 167.330 151.322 1.00 46.41  ? 495 PRO   A CG  1 
ATOM   3803 C CD  . PRO   A 1 469 ? 147.013 168.749 151.268 1.00 47.13  ? 495 PRO   A CD  1 
ATOM   3804 N N   . PHE   A 1 470 ? 145.434 169.518 148.035 1.00 49.49  ? 496 PHE   A N   1 
ATOM   3805 C CA  . PHE   A 1 470 ? 144.448 170.012 147.083 1.00 47.70  ? 496 PHE   A CA  1 
ATOM   3806 C C   . PHE   A 1 470 ? 144.972 171.132 146.188 1.00 49.50  ? 496 PHE   A C   1 
ATOM   3807 O O   . PHE   A 1 470 ? 144.171 171.794 145.522 1.00 54.65  ? 496 PHE   A O   1 
ATOM   3808 C CB  . PHE   A 1 470 ? 143.205 170.484 147.834 1.00 46.56  ? 496 PHE   A CB  1 
ATOM   3809 C CG  . PHE   A 1 470 ? 142.615 169.438 148.733 1.00 49.34  ? 496 PHE   A CG  1 
ATOM   3810 C CD1 . PHE   A 1 470 ? 141.977 168.333 148.203 1.00 49.45  ? 496 PHE   A CD1 1 
ATOM   3811 C CD2 . PHE   A 1 470 ? 142.699 169.558 150.106 1.00 49.34  ? 496 PHE   A CD2 1 
ATOM   3812 C CE1 . PHE   A 1 470 ? 141.437 167.368 149.024 1.00 48.55  ? 496 PHE   A CE1 1 
ATOM   3813 C CE2 . PHE   A 1 470 ? 142.160 168.597 150.932 1.00 51.22  ? 496 PHE   A CE2 1 
ATOM   3814 C CZ  . PHE   A 1 470 ? 141.528 167.501 150.391 1.00 49.64  ? 496 PHE   A CZ  1 
ATOM   3815 N N   . GLN   A 1 471 ? 146.284 171.366 146.161 1.00 48.95  ? 497 GLN   A N   1 
ATOM   3816 C CA  . GLN   A 1 471 ? 146.898 172.332 145.259 1.00 49.39  ? 497 GLN   A CA  1 
ATOM   3817 C C   . GLN   A 1 471 ? 148.140 171.714 144.641 1.00 50.74  ? 497 GLN   A C   1 
ATOM   3818 O O   . GLN   A 1 471 ? 148.844 170.935 145.288 1.00 51.16  ? 497 GLN   A O   1 
ATOM   3819 C CB  . GLN   A 1 471 ? 147.259 173.631 145.983 1.00 50.77  ? 497 GLN   A CB  1 
ATOM   3820 C CG  . GLN   A 1 471 ? 146.082 174.308 146.662 1.00 57.53  ? 497 GLN   A CG  1 
ATOM   3821 C CD  . GLN   A 1 471 ? 146.468 175.610 147.331 1.00 66.39  ? 497 GLN   A CD  1 
ATOM   3822 O OE1 . GLN   A 1 471 ? 147.594 176.085 147.186 1.00 66.77  ? 497 GLN   A OE1 1 
ATOM   3823 N NE2 . GLN   A 1 471 ? 145.533 176.195 148.071 1.00 69.21  ? 497 GLN   A NE2 1 
ATOM   3824 N N   . ARG   A 1 472 ? 148.400 172.060 143.384 1.00 51.17  ? 498 ARG   A N   1 
ATOM   3825 C CA  . ARG   A 1 472 ? 149.480 171.431 142.639 1.00 54.11  ? 498 ARG   A CA  1 
ATOM   3826 C C   . ARG   A 1 472 ? 150.838 171.889 143.155 1.00 59.61  ? 498 ARG   A C   1 
ATOM   3827 O O   . ARG   A 1 472 ? 151.042 173.067 143.460 1.00 59.38  ? 498 ARG   A O   1 
ATOM   3828 C CB  . ARG   A 1 472 ? 149.350 171.755 141.154 1.00 57.76  ? 498 ARG   A CB  1 
ATOM   3829 C CG  . ARG   A 1 472 ? 150.150 170.835 140.251 1.00 61.70  ? 498 ARG   A CG  1 
ATOM   3830 C CD  . ARG   A 1 472 ? 150.079 171.279 138.799 1.00 70.34  ? 498 ARG   A CD  1 
ATOM   3831 N NE  . ARG   A 1 472 ? 148.712 171.293 138.290 1.00 77.92  ? 498 ARG   A NE  1 
ATOM   3832 C CZ  . ARG   A 1 472 ? 148.359 171.676 137.069 1.00 84.45  ? 498 ARG   A CZ  1 
ATOM   3833 N NH1 . ARG   A 1 472 ? 149.252 172.094 136.184 1.00 83.96  ? 498 ARG   A NH1 1 
ATOM   3834 N NH2 . ARG   A 1 472 ? 147.075 171.641 136.725 1.00 81.14  ? 498 ARG   A NH2 1 
ATOM   3835 N N   . THR   A 1 473 ? 151.770 170.943 143.251 1.00 60.11  ? 499 THR   A N   1 
ATOM   3836 C CA  . THR   A 1 473 ? 153.136 171.249 143.650 1.00 49.09  ? 499 THR   A CA  1 
ATOM   3837 C C   . THR   A 1 473 ? 153.875 171.910 142.495 1.00 47.68  ? 499 THR   A C   1 
ATOM   3838 O O   . THR   A 1 473 ? 153.800 171.446 141.353 1.00 49.69  ? 499 THR   A O   1 
ATOM   3839 C CB  . THR   A 1 473 ? 153.865 169.977 144.079 1.00 46.32  ? 499 THR   A CB  1 
ATOM   3840 O OG1 . THR   A 1 473 ? 153.902 169.055 142.984 1.00 48.37  ? 499 THR   A OG1 1 
ATOM   3841 C CG2 . THR   A 1 473 ? 153.162 169.328 145.248 1.00 48.28  ? 499 THR   A CG2 1 
ATOM   3842 N N   . SER   A 1 474 ? 154.595 172.985 142.793 1.00 48.26  ? 500 SER   A N   1 
ATOM   3843 C CA  . SER   A 1 474 ? 155.279 173.771 141.777 1.00 49.33  ? 500 SER   A CA  1 
ATOM   3844 C C   . SER   A 1 474 ? 156.711 173.319 141.513 1.00 50.67  ? 500 SER   A C   1 
ATOM   3845 O O   . SER   A 1 474 ? 157.358 173.882 140.623 1.00 51.68  ? 500 SER   A O   1 
ATOM   3846 C CB  . SER   A 1 474 ? 155.283 175.246 142.184 1.00 52.62  ? 500 SER   A CB  1 
ATOM   3847 O OG  . SER   A 1 474 ? 155.837 175.414 143.476 1.00 52.04  ? 500 SER   A OG  1 
ATOM   3848 N N   . TRP   A 1 475 ? 157.219 172.326 142.245 1.00 48.73  ? 501 TRP   A N   1 
ATOM   3849 C CA  . TRP   A 1 475 ? 158.602 171.868 142.134 1.00 45.83  ? 501 TRP   A CA  1 
ATOM   3850 C C   . TRP   A 1 475 ? 158.660 170.416 141.673 1.00 44.07  ? 501 TRP   A C   1 
ATOM   3851 O O   . TRP   A 1 475 ? 159.477 169.623 142.144 1.00 47.02  ? 501 TRP   A O   1 
ATOM   3852 C CB  . TRP   A 1 475 ? 159.353 172.068 143.455 1.00 44.55  ? 501 TRP   A CB  1 
ATOM   3853 C CG  . TRP   A 1 475 ? 158.582 171.717 144.691 1.00 41.98  ? 501 TRP   A CG  1 
ATOM   3854 C CD1 . TRP   A 1 475 ? 157.770 172.542 145.405 1.00 45.99  ? 501 TRP   A CD1 1 
ATOM   3855 C CD2 . TRP   A 1 475 ? 158.558 170.454 145.364 1.00 42.01  ? 501 TRP   A CD2 1 
ATOM   3856 N NE1 . TRP   A 1 475 ? 157.237 171.874 146.476 1.00 48.27  ? 501 TRP   A NE1 1 
ATOM   3857 C CE2 . TRP   A 1 475 ? 157.706 170.589 146.473 1.00 44.81  ? 501 TRP   A CE2 1 
ATOM   3858 C CE3 . TRP   A 1 475 ? 159.174 169.222 145.135 1.00 45.33  ? 501 TRP   A CE3 1 
ATOM   3859 C CZ2 . TRP   A 1 475 ? 157.453 169.541 147.349 1.00 44.73  ? 501 TRP   A CZ2 1 
ATOM   3860 C CZ3 . TRP   A 1 475 ? 158.919 168.183 146.006 1.00 46.15  ? 501 TRP   A CZ3 1 
ATOM   3861 C CH2 . TRP   A 1 475 ? 158.067 168.348 147.098 1.00 43.68  ? 501 TRP   A CH2 1 
ATOM   3862 N N   . VAL   A 1 476 ? 157.793 170.058 140.730 1.00 41.69  ? 502 VAL   A N   1 
ATOM   3863 C CA  . VAL   A 1 476 ? 157.831 168.770 140.046 1.00 39.88  ? 502 VAL   A CA  1 
ATOM   3864 C C   . VAL   A 1 476 ? 157.978 169.060 138.562 1.00 40.77  ? 502 VAL   A C   1 
ATOM   3865 O O   . VAL   A 1 476 ? 157.106 169.699 137.960 1.00 43.17  ? 502 VAL   A O   1 
ATOM   3866 C CB  . VAL   A 1 476 ? 156.576 167.928 140.323 1.00 43.17  ? 502 VAL   A CB  1 
ATOM   3867 C CG1 . VAL   A 1 476 ? 156.647 166.606 139.578 1.00 44.22  ? 502 VAL   A CG1 1 
ATOM   3868 C CG2 . VAL   A 1 476 ? 156.411 167.687 141.813 1.00 45.89  ? 502 VAL   A CG2 1 
ATOM   3869 N N   . GLN   A 1 477 ? 159.073 168.598 137.976 1.00 41.78  ? 503 GLN   A N   1 
ATOM   3870 C CA  . GLN   A 1 477 ? 159.357 168.924 136.591 1.00 42.73  ? 503 GLN   A CA  1 
ATOM   3871 C C   . GLN   A 1 477 ? 158.338 168.251 135.672 1.00 40.95  ? 503 GLN   A C   1 
ATOM   3872 O O   . GLN   A 1 477 ? 157.942 167.108 135.924 1.00 46.32  ? 503 GLN   A O   1 
ATOM   3873 C CB  . GLN   A 1 477 ? 160.767 168.474 136.214 1.00 43.80  ? 503 GLN   A CB  1 
ATOM   3874 C CG  . GLN   A 1 477 ? 161.882 169.144 136.998 1.00 43.71  ? 503 GLN   A CG  1 
ATOM   3875 C CD  . GLN   A 1 477 ? 162.031 170.613 136.671 1.00 48.93  ? 503 GLN   A CD  1 
ATOM   3876 O OE1 . GLN   A 1 477 ? 161.333 171.144 135.810 1.00 52.56  ? 503 GLN   A OE1 1 
ATOM   3877 N NE2 . GLN   A 1 477 ? 162.949 171.278 137.356 1.00 47.55  ? 503 GLN   A NE2 1 
ATOM   3878 N N   . PRO   A 1 478 ? 157.888 168.918 134.607 1.00 37.99  ? 504 PRO   A N   1 
ATOM   3879 C CA  . PRO   A 1 478 ? 156.973 168.253 133.676 1.00 38.69  ? 504 PRO   A CA  1 
ATOM   3880 C C   . PRO   A 1 478 ? 157.650 167.106 132.950 1.00 38.53  ? 504 PRO   A C   1 
ATOM   3881 O O   . PRO   A 1 478 ? 158.858 167.121 132.706 1.00 42.71  ? 504 PRO   A O   1 
ATOM   3882 C CB  . PRO   A 1 478 ? 156.580 169.368 132.704 1.00 41.98  ? 504 PRO   A CB  1 
ATOM   3883 C CG  . PRO   A 1 478 ? 157.710 170.300 132.742 1.00 40.61  ? 504 PRO   A CG  1 
ATOM   3884 C CD  . PRO   A 1 478 ? 158.204 170.283 134.147 1.00 40.40  ? 504 PRO   A CD  1 
ATOM   3885 N N   . LEU   A 1 479 ? 156.855 166.102 132.603 1.00 37.86  ? 505 LEU   A N   1 
ATOM   3886 C CA  . LEU   A 1 479 ? 157.355 165.014 131.775 1.00 38.87  ? 505 LEU   A CA  1 
ATOM   3887 C C   . LEU   A 1 479 ? 157.489 165.513 130.346 1.00 43.08  ? 505 LEU   A C   1 
ATOM   3888 O O   . LEU   A 1 479 ? 156.505 165.944 129.736 1.00 47.86  ? 505 LEU   A O   1 
ATOM   3889 C CB  . LEU   A 1 479 ? 156.414 163.814 131.840 1.00 41.59  ? 505 LEU   A CB  1 
ATOM   3890 C CG  . LEU   A 1 479 ? 156.983 162.414 131.570 1.00 40.97  ? 505 LEU   A CG  1 
ATOM   3891 C CD1 . LEU   A 1 479 ? 155.873 161.384 131.632 1.00 43.63  ? 505 LEU   A CD1 1 
ATOM   3892 C CD2 . LEU   A 1 479 ? 157.698 162.309 130.241 1.00 41.96  ? 505 LEU   A CD2 1 
ATOM   3893 N N   . LEU   A 1 480 ? 158.702 165.458 129.810 1.00 42.11  ? 506 LEU   A N   1 
ATOM   3894 C CA  . LEU   A 1 480 ? 158.952 165.869 128.434 1.00 43.53  ? 506 LEU   A CA  1 
ATOM   3895 C C   . LEU   A 1 480 ? 158.456 164.760 127.520 1.00 45.93  ? 506 LEU   A C   1 
ATOM   3896 O O   . LEU   A 1 480 ? 159.205 163.867 127.125 1.00 46.41  ? 506 LEU   A O   1 
ATOM   3897 C CB  . LEU   A 1 480 ? 160.431 166.156 128.215 1.00 43.79  ? 506 LEU   A CB  1 
ATOM   3898 C CG  . LEU   A 1 480 ? 161.058 167.311 128.996 1.00 43.82  ? 506 LEU   A CG  1 
ATOM   3899 C CD1 . LEU   A 1 480 ? 162.553 167.327 128.778 1.00 45.51  ? 506 LEU   A CD1 1 
ATOM   3900 C CD2 . LEU   A 1 480 ? 160.448 168.640 128.590 1.00 45.40  ? 506 LEU   A CD2 1 
ATOM   3901 N N   . MET   A 1 481 ? 157.170 164.817 127.180 1.00 46.96  ? 507 MET   A N   1 
ATOM   3902 C CA  . MET   A 1 481 ? 156.591 163.861 126.248 1.00 51.81  ? 507 MET   A CA  1 
ATOM   3903 C C   . MET   A 1 481 ? 156.872 164.211 124.794 1.00 55.86  ? 507 MET   A C   1 
ATOM   3904 O O   . MET   A 1 481 ? 156.517 163.427 123.907 1.00 60.31  ? 507 MET   A O   1 
ATOM   3905 C CB  . MET   A 1 481 ? 155.080 163.760 126.464 1.00 55.14  ? 507 MET   A CB  1 
ATOM   3906 C CG  . MET   A 1 481 ? 154.695 163.277 127.848 1.00 56.12  ? 507 MET   A CG  1 
ATOM   3907 S SD  . MET   A 1 481 ? 152.993 162.699 127.957 1.00 79.56  ? 507 MET   A SD  1 
ATOM   3908 C CE  . MET   A 1 481 ? 153.118 161.132 127.101 1.00 62.50  ? 507 MET   A CE  1 
ATOM   3909 N N   . ASP   A 1 482 ? 157.496 165.360 124.524 1.00 51.85  ? 508 ASP   A N   1 
ATOM   3910 C CA  . ASP   A 1 482 ? 157.837 165.704 123.150 1.00 52.91  ? 508 ASP   A CA  1 
ATOM   3911 C C   . ASP   A 1 482 ? 158.898 164.770 122.581 1.00 54.50  ? 508 ASP   A C   1 
ATOM   3912 O O   . ASP   A 1 482 ? 158.945 164.564 121.364 1.00 55.77  ? 508 ASP   A O   1 
ATOM   3913 C CB  . ASP   A 1 482 ? 158.315 167.153 123.082 1.00 59.12  ? 508 ASP   A CB  1 
ATOM   3914 C CG  . ASP   A 1 482 ? 157.286 168.127 123.615 1.00 68.40  ? 508 ASP   A CG  1 
ATOM   3915 O OD1 . ASP   A 1 482 ? 156.219 167.668 124.072 1.00 69.09  ? 508 ASP   A OD1 1 
ATOM   3916 O OD2 . ASP   A 1 482 ? 157.542 169.349 123.578 1.00 72.44  ? 508 ASP   A OD2 1 
ATOM   3917 N N   . LEU   A 1 483 ? 159.746 164.194 123.434 1.00 53.54  ? 509 LEU   A N   1 
ATOM   3918 C CA  . LEU   A 1 483 ? 160.798 163.281 123.008 1.00 51.78  ? 509 LEU   A CA  1 
ATOM   3919 C C   . LEU   A 1 483 ? 160.327 161.827 122.946 1.00 50.35  ? 509 LEU   A C   1 
ATOM   3920 O O   . LEU   A 1 483 ? 161.153 160.912 123.021 1.00 51.69  ? 509 LEU   A O   1 
ATOM   3921 C CB  . LEU   A 1 483 ? 162.013 163.401 123.937 1.00 48.59  ? 509 LEU   A CB  1 
ATOM   3922 C CG  . LEU   A 1 483 ? 162.766 164.737 124.069 1.00 47.36  ? 509 LEU   A CG  1 
ATOM   3923 C CD1 . LEU   A 1 483 ? 162.923 165.460 122.734 1.00 51.62  ? 509 LEU   A CD1 1 
ATOM   3924 C CD2 . LEU   A 1 483 ? 162.121 165.650 125.092 1.00 47.63  ? 509 LEU   A CD2 1 
ATOM   3925 N N   . SER   A 1 484 ? 159.022 161.599 122.817 1.00 46.34  ? 510 SER   A N   1 
ATOM   3926 C CA  . SER   A 1 484 ? 158.505 160.234 122.733 1.00 48.64  ? 510 SER   A CA  1 
ATOM   3927 C C   . SER   A 1 484 ? 159.034 159.444 121.539 1.00 50.73  ? 510 SER   A C   1 
ATOM   3928 O O   . SER   A 1 484 ? 159.465 158.297 121.741 1.00 51.95  ? 510 SER   A O   1 
ATOM   3929 C CB  . SER   A 1 484 ? 156.975 160.277 122.720 1.00 57.61  ? 510 SER   A CB  1 
ATOM   3930 O OG  . SER   A 1 484 ? 156.471 160.825 123.926 1.00 64.03  ? 510 SER   A OG  1 
ATOM   3931 N N   . PRO   A 1 485 ? 159.010 159.946 120.295 1.00 51.52  ? 511 PRO   A N   1 
ATOM   3932 C CA  . PRO   A 1 485 ? 159.453 159.097 119.172 1.00 49.81  ? 511 PRO   A CA  1 
ATOM   3933 C C   . PRO   A 1 485 ? 160.915 158.690 119.237 1.00 50.33  ? 511 PRO   A C   1 
ATOM   3934 O O   . PRO   A 1 485 ? 161.275 157.641 118.677 1.00 53.60  ? 511 PRO   A O   1 
ATOM   3935 C CB  . PRO   A 1 485 ? 159.162 159.958 117.936 1.00 50.60  ? 511 PRO   A CB  1 
ATOM   3936 C CG  . PRO   A 1 485 ? 159.029 161.331 118.434 1.00 53.51  ? 511 PRO   A CG  1 
ATOM   3937 C CD  . PRO   A 1 485 ? 158.472 161.230 119.807 1.00 52.70  ? 511 PRO   A CD  1 
ATOM   3938 N N   . TRP   A 1 486 ? 161.756 159.445 119.954 1.00 46.46  ? 512 TRP   A N   1 
ATOM   3939 C CA  . TRP   A 1 486 ? 163.176 159.124 120.050 1.00 48.63  ? 512 TRP   A CA  1 
ATOM   3940 C C   . TRP   A 1 486 ? 163.418 157.718 120.574 1.00 51.40  ? 512 TRP   A C   1 
ATOM   3941 O O   . TRP   A 1 486 ? 164.458 157.127 120.264 1.00 55.23  ? 512 TRP   A O   1 
ATOM   3942 C CB  . TRP   A 1 486 ? 163.887 160.111 120.974 1.00 48.72  ? 512 TRP   A CB  1 
ATOM   3943 C CG  . TRP   A 1 486 ? 164.181 161.447 120.381 1.00 46.85  ? 512 TRP   A CG  1 
ATOM   3944 C CD1 . TRP   A 1 486 ? 163.370 162.540 120.389 1.00 50.36  ? 512 TRP   A CD1 1 
ATOM   3945 C CD2 . TRP   A 1 486 ? 165.382 161.844 119.713 1.00 40.95  ? 512 TRP   A CD2 1 
ATOM   3946 N NE1 . TRP   A 1 486 ? 163.987 163.592 119.760 1.00 50.69  ? 512 TRP   A NE1 1 
ATOM   3947 C CE2 . TRP   A 1 486 ? 165.225 163.189 119.338 1.00 42.78  ? 512 TRP   A CE2 1 
ATOM   3948 C CE3 . TRP   A 1 486 ? 166.572 161.191 119.393 1.00 41.90  ? 512 TRP   A CE3 1 
ATOM   3949 C CZ2 . TRP   A 1 486 ? 166.209 163.889 118.655 1.00 43.88  ? 512 TRP   A CZ2 1 
ATOM   3950 C CZ3 . TRP   A 1 486 ? 167.545 161.886 118.717 1.00 42.92  ? 512 TRP   A CZ3 1 
ATOM   3951 C CH2 . TRP   A 1 486 ? 167.361 163.222 118.356 1.00 44.62  ? 512 TRP   A CH2 1 
ATOM   3952 N N   . ARG   A 1 487 ? 162.460 157.155 121.316 1.00 48.99  ? 513 ARG   A N   1 
ATOM   3953 C CA  . ARG   A 1 487 ? 162.601 155.815 121.865 1.00 48.92  ? 513 ARG   A CA  1 
ATOM   3954 C C   . ARG   A 1 487 ? 162.871 154.774 120.793 1.00 49.40  ? 513 ARG   A C   1 
ATOM   3955 O O   . ARG   A 1 487 ? 163.442 153.723 121.100 1.00 55.35  ? 513 ARG   A O   1 
ATOM   3956 C CB  . ARG   A 1 487 ? 161.345 155.434 122.639 1.00 45.61  ? 513 ARG   A CB  1 
ATOM   3957 C CG  . ARG   A 1 487 ? 161.056 156.340 123.809 1.00 46.05  ? 513 ARG   A CG  1 
ATOM   3958 C CD  . ARG   A 1 487 ? 159.891 155.825 124.621 1.00 48.02  ? 513 ARG   A CD  1 
ATOM   3959 N NE  . ARG   A 1 487 ? 158.620 156.055 123.947 1.00 48.24  ? 513 ARG   A NE  1 
ATOM   3960 C CZ  . ARG   A 1 487 ? 157.443 155.626 124.382 1.00 50.20  ? 513 ARG   A CZ  1 
ATOM   3961 N NH1 . ARG   A 1 487 ? 157.329 154.904 125.485 1.00 49.15  ? 513 ARG   A NH1 1 
ATOM   3962 N NH2 . ARG   A 1 487 ? 156.348 155.931 123.693 1.00 54.74  ? 513 ARG   A NH2 1 
ATOM   3963 N N   . ALA   A 1 488 ? 162.479 155.029 119.545 1.00 47.86  ? 514 ALA   A N   1 
ATOM   3964 C CA  . ALA   A 1 488 ? 162.901 154.136 118.476 1.00 51.63  ? 514 ALA   A CA  1 
ATOM   3965 C C   . ALA   A 1 488 ? 164.405 154.248 118.252 1.00 53.92  ? 514 ALA   A C   1 
ATOM   3966 O O   . ALA   A 1 488 ? 165.150 153.280 118.459 1.00 57.15  ? 514 ALA   A O   1 
ATOM   3967 C CB  . ALA   A 1 488 ? 162.134 154.456 117.193 1.00 55.07  ? 514 ALA   A CB  1 
ATOM   3968 N N   . LYS   A 1 489 ? 164.875 155.450 117.898 1.00 56.38  ? 515 LYS   A N   1 
ATOM   3969 C CA  . LYS   A 1 489 ? 166.254 155.618 117.446 1.00 54.65  ? 515 LYS   A CA  1 
ATOM   3970 C C   . LYS   A 1 489 ? 167.246 155.229 118.529 1.00 54.43  ? 515 LYS   A C   1 
ATOM   3971 O O   . LYS   A 1 489 ? 168.233 154.533 118.254 1.00 58.50  ? 515 LYS   A O   1 
ATOM   3972 C CB  . LYS   A 1 489 ? 166.495 157.062 117.009 1.00 54.44  ? 515 LYS   A CB  1 
ATOM   3973 C CG  . LYS   A 1 489 ? 165.610 157.526 115.859 1.00 63.46  ? 515 LYS   A CG  1 
ATOM   3974 C CD  . LYS   A 1 489 ? 165.809 159.006 115.531 1.00 66.25  ? 515 LYS   A CD  1 
ATOM   3975 C CE  . LYS   A 1 489 ? 167.187 159.310 114.945 1.00 69.99  ? 515 LYS   A CE  1 
ATOM   3976 N NZ  . LYS   A 1 489 ? 167.477 158.535 113.705 1.00 70.28  ? 515 LYS   A NZ  1 
ATOM   3977 N N   . LEU   A 1 490 ? 166.982 155.645 119.769 1.00 55.99  ? 516 LEU   A N   1 
ATOM   3978 C CA  . LEU   A 1 490 ? 167.872 155.313 120.875 1.00 54.71  ? 516 LEU   A CA  1 
ATOM   3979 C C   . LEU   A 1 490 ? 168.047 153.809 120.999 1.00 52.56  ? 516 LEU   A C   1 
ATOM   3980 O O   . LEU   A 1 490 ? 169.163 153.324 121.225 1.00 58.18  ? 516 LEU   A O   1 
ATOM   3981 C CB  . LEU   A 1 490 ? 167.328 155.898 122.176 1.00 53.34  ? 516 LEU   A CB  1 
ATOM   3982 C CG  . LEU   A 1 490 ? 167.098 157.411 122.222 1.00 53.12  ? 516 LEU   A CG  1 
ATOM   3983 C CD1 . LEU   A 1 490 ? 166.454 157.817 123.540 1.00 49.26  ? 516 LEU   A CD1 1 
ATOM   3984 C CD2 . LEU   A 1 490 ? 168.387 158.184 122.006 1.00 52.06  ? 516 LEU   A CD2 1 
ATOM   3985 N N   . GLN   A 1 491 ? 166.962 153.053 120.814 1.00 51.27  ? 517 GLN   A N   1 
ATOM   3986 C CA  . GLN   A 1 491 ? 167.053 151.603 120.934 1.00 55.24  ? 517 GLN   A CA  1 
ATOM   3987 C C   . GLN   A 1 491 ? 168.023 151.038 119.906 1.00 58.23  ? 517 GLN   A C   1 
ATOM   3988 O O   . GLN   A 1 491 ? 168.782 150.109 120.207 1.00 61.13  ? 517 GLN   A O   1 
ATOM   3989 C CB  . GLN   A 1 491 ? 165.666 150.979 120.784 1.00 57.26  ? 517 GLN   A CB  1 
ATOM   3990 C CG  . GLN   A 1 491 ? 165.556 149.540 121.285 1.00 59.03  ? 517 GLN   A CG  1 
ATOM   3991 C CD  . GLN   A 1 491 ? 165.993 148.501 120.265 1.00 71.54  ? 517 GLN   A CD  1 
ATOM   3992 O OE1 . GLN   A 1 491 ? 166.228 148.811 119.097 1.00 73.17  ? 517 GLN   A OE1 1 
ATOM   3993 N NE2 . GLN   A 1 491 ? 166.099 147.254 120.708 1.00 73.60  ? 517 GLN   A NE2 1 
ATOM   3994 N N   . GLU   A 1 492 ? 168.039 151.614 118.700 1.00 56.67  ? 518 GLU   A N   1 
ATOM   3995 C CA  . GLU   A 1 492 ? 169.010 151.197 117.695 1.00 57.76  ? 518 GLU   A CA  1 
ATOM   3996 C C   . GLU   A 1 492 ? 170.429 151.363 118.219 1.00 60.26  ? 518 GLU   A C   1 
ATOM   3997 O O   . GLU   A 1 492 ? 171.259 150.452 118.101 1.00 62.44  ? 518 GLU   A O   1 
ATOM   3998 C CB  . GLU   A 1 492 ? 168.812 152.001 116.411 1.00 60.00  ? 518 GLU   A CB  1 
ATOM   3999 C CG  . GLU   A 1 492 ? 169.600 151.479 115.221 1.00 67.89  ? 518 GLU   A CG  1 
ATOM   4000 C CD  . GLU   A 1 492 ? 169.339 152.278 113.959 1.00 76.40  ? 518 GLU   A CD  1 
ATOM   4001 O OE1 . GLU   A 1 492 ? 168.518 153.218 114.008 1.00 78.71  ? 518 GLU   A OE1 1 
ATOM   4002 O OE2 . GLU   A 1 492 ? 169.956 151.968 112.919 1.00 75.10  ? 518 GLU   A OE2 1 
ATOM   4003 N N   . ILE   A 1 493 ? 170.712 152.507 118.846 1.00 56.72  ? 519 ILE   A N   1 
ATOM   4004 C CA  . ILE   A 1 493 ? 172.047 152.735 119.391 1.00 50.35  ? 519 ILE   A CA  1 
ATOM   4005 C C   . ILE   A 1 493 ? 172.341 151.730 120.493 1.00 52.75  ? 519 ILE   A C   1 
ATOM   4006 O O   . ILE   A 1 493 ? 173.495 151.342 120.708 1.00 60.33  ? 519 ILE   A O   1 
ATOM   4007 C CB  . ILE   A 1 493 ? 172.196 154.187 119.885 1.00 49.99  ? 519 ILE   A CB  1 
ATOM   4008 C CG1 . ILE   A 1 493 ? 172.076 155.171 118.712 1.00 50.71  ? 519 ILE   A CG1 1 
ATOM   4009 C CG2 . ILE   A 1 493 ? 173.538 154.358 120.589 1.00 50.99  ? 519 ILE   A CG2 1 
ATOM   4010 C CD1 . ILE   A 1 493 ? 171.878 156.615 119.119 1.00 48.56  ? 519 ILE   A CD1 1 
ATOM   4011 N N   . LYS   A 1 494 ? 171.306 151.288 121.210 1.00 52.69  ? 520 LYS   A N   1 
ATOM   4012 C CA  . LYS   A 1 494 ? 171.515 150.283 122.240 1.00 55.54  ? 520 LYS   A CA  1 
ATOM   4013 C C   . LYS   A 1 494 ? 171.962 148.951 121.654 1.00 58.10  ? 520 LYS   A C   1 
ATOM   4014 O O   . LYS   A 1 494 ? 172.659 148.195 122.340 1.00 62.67  ? 520 LYS   A O   1 
ATOM   4015 C CB  . LYS   A 1 494 ? 170.232 150.091 123.054 1.00 57.65  ? 520 LYS   A CB  1 
ATOM   4016 C CG  . LYS   A 1 494 ? 170.382 149.269 124.338 1.00 61.58  ? 520 LYS   A CG  1 
ATOM   4017 C CD  . LYS   A 1 494 ? 171.195 149.962 125.430 1.00 63.04  ? 520 LYS   A CD  1 
ATOM   4018 C CE  . LYS   A 1 494 ? 170.549 151.249 125.940 1.00 64.55  ? 520 LYS   A CE  1 
ATOM   4019 N NZ  . LYS   A 1 494 ? 169.130 151.075 126.356 1.00 69.05  ? 520 LYS   A NZ  1 
ATOM   4020 N N   . SER   A 1 495 ? 171.591 148.649 120.409 1.00 55.62  ? 521 SER   A N   1 
ATOM   4021 C CA  . SER   A 1 495 ? 171.898 147.362 119.796 1.00 55.19  ? 521 SER   A CA  1 
ATOM   4022 C C   . SER   A 1 495 ? 173.142 147.391 118.918 1.00 55.15  ? 521 SER   A C   1 
ATOM   4023 O O   . SER   A 1 495 ? 173.471 146.370 118.308 1.00 60.45  ? 521 SER   A O   1 
ATOM   4024 C CB  . SER   A 1 495 ? 170.703 146.880 118.969 1.00 61.35  ? 521 SER   A CB  1 
ATOM   4025 O OG  . SER   A 1 495 ? 170.412 147.781 117.915 1.00 68.58  ? 521 SER   A OG  1 
ATOM   4026 N N   . SER   A 1 496 ? 173.842 148.521 118.839 1.00 51.06  ? 522 SER   A N   1 
ATOM   4027 C CA  . SER   A 1 496 ? 175.033 148.664 118.013 1.00 52.69  ? 522 SER   A CA  1 
ATOM   4028 C C   . SER   A 1 496 ? 176.320 148.514 118.810 1.00 53.53  ? 522 SER   A C   1 
ATOM   4029 O O   . SER   A 1 496 ? 177.399 148.793 118.280 1.00 59.53  ? 522 SER   A O   1 
ATOM   4030 C CB  . SER   A 1 496 ? 175.017 150.021 117.308 1.00 57.44  ? 522 SER   A CB  1 
ATOM   4031 O OG  . SER   A 1 496 ? 176.191 150.213 116.539 1.00 65.25  ? 522 SER   A OG  1 
ATOM   4032 N N   . LEU   A 1 497 ? 176.234 148.077 120.060 1.00 54.99  ? 523 LEU   A N   1 
ATOM   4033 C CA  . LEU   A 1 497 ? 177.357 148.092 120.982 1.00 57.48  ? 523 LEU   A CA  1 
ATOM   4034 C C   . LEU   A 1 497 ? 177.991 146.711 121.083 1.00 59.01  ? 523 LEU   A C   1 
ATOM   4035 O O   . LEU   A 1 497 ? 177.432 145.701 120.651 1.00 66.28  ? 523 LEU   A O   1 
ATOM   4036 C CB  . LEU   A 1 497 ? 176.898 148.560 122.365 1.00 59.51  ? 523 LEU   A CB  1 
ATOM   4037 C CG  . LEU   A 1 497 ? 176.165 149.901 122.431 1.00 57.56  ? 523 LEU   A CG  1 
ATOM   4038 C CD1 . LEU   A 1 497 ? 175.574 150.105 123.811 1.00 55.39  ? 523 LEU   A CD1 1 
ATOM   4039 C CD2 . LEU   A 1 497 ? 177.094 151.041 122.072 1.00 56.58  ? 523 LEU   A CD2 1 
ATOM   4040 N N   . ASP   A 1 498 ? 179.179 146.683 121.673 1.00 58.24  ? 524 ASP   A N   1 
ATOM   4041 C CA  . ASP   A 1 498 ? 179.890 145.442 121.936 1.00 61.85  ? 524 ASP   A CA  1 
ATOM   4042 C C   . ASP   A 1 498 ? 179.365 144.835 123.234 1.00 65.01  ? 524 ASP   A C   1 
ATOM   4043 O O   . ASP   A 1 498 ? 178.356 145.274 123.792 1.00 68.09  ? 524 ASP   A O   1 
ATOM   4044 C CB  . ASP   A 1 498 ? 181.392 145.701 121.993 1.00 68.49  ? 524 ASP   A CB  1 
ATOM   4045 C CG  . ASP   A 1 498 ? 181.889 146.494 120.806 1.00 74.78  ? 524 ASP   A CG  1 
ATOM   4046 O OD1 . ASP   A 1 498 ? 181.060 146.869 119.952 1.00 75.83  ? 524 ASP   A OD1 1 
ATOM   4047 O OD2 . ASP   A 1 498 ? 183.110 146.745 120.727 1.00 75.90  ? 524 ASP   A OD2 1 
ATOM   4048 N N   . ASN   A 1 499 ? 180.049 143.809 123.730 1.00 67.79  ? 525 ASN   A N   1 
ATOM   4049 C CA  . ASN   A 1 499 ? 179.713 143.208 125.013 1.00 68.83  ? 525 ASN   A CA  1 
ATOM   4050 C C   . ASN   A 1 499 ? 180.230 144.008 126.204 1.00 70.79  ? 525 ASN   A C   1 
ATOM   4051 O O   . ASN   A 1 499 ? 179.915 143.647 127.343 1.00 71.35  ? 525 ASN   A O   1 
ATOM   4052 C CB  . ASN   A 1 499 ? 180.262 141.783 125.079 1.00 71.02  ? 525 ASN   A CB  1 
ATOM   4053 C CG  . ASN   A 1 499 ? 179.686 140.887 124.002 1.00 76.63  ? 525 ASN   A CG  1 
ATOM   4054 O OD1 . ASN   A 1 499 ? 179.211 141.364 122.972 1.00 75.48  ? 525 ASN   A OD1 1 
ATOM   4055 N ND2 . ASN   A 1 499 ? 179.723 139.581 124.235 1.00 76.28  ? 525 ASN   A ND2 1 
ATOM   4056 N N   . HIS   A 1 500 ? 181.003 145.071 125.977 1.00 71.17  ? 526 HIS   A N   1 
ATOM   4057 C CA  . HIS   A 1 500 ? 181.577 145.893 127.039 1.00 69.20  ? 526 HIS   A CA  1 
ATOM   4058 C C   . HIS   A 1 500 ? 180.972 147.283 127.116 1.00 63.77  ? 526 HIS   A C   1 
ATOM   4059 O O   . HIS   A 1 500 ? 180.729 147.784 128.216 1.00 63.10  ? 526 HIS   A O   1 
ATOM   4060 C CB  . HIS   A 1 500 ? 183.088 146.036 126.837 1.00 68.22  ? 526 HIS   A CB  1 
ATOM   4061 C CG  . HIS   A 1 500 ? 183.743 144.817 126.270 1.00 74.34  ? 526 HIS   A CG  1 
ATOM   4062 N ND1 . HIS   A 1 500 ? 183.865 143.641 126.977 1.00 80.75  ? 526 HIS   A ND1 1 
ATOM   4063 C CD2 . HIS   A 1 500 ? 184.321 144.595 125.067 1.00 75.35  ? 526 HIS   A CD2 1 
ATOM   4064 C CE1 . HIS   A 1 500 ? 184.485 142.744 126.231 1.00 82.21  ? 526 HIS   A CE1 1 
ATOM   4065 N NE2 . HIS   A 1 500 ? 184.773 143.298 125.067 1.00 83.08  ? 526 HIS   A NE2 1 
ATOM   4066 N N   . THR   A 1 501 ? 180.729 147.917 125.975 1.00 56.43  ? 527 THR   A N   1 
ATOM   4067 C CA  . THR   A 1 501 ? 180.284 149.300 125.956 1.00 51.10  ? 527 THR   A CA  1 
ATOM   4068 C C   . THR   A 1 501 ? 178.881 149.428 126.538 1.00 51.69  ? 527 THR   A C   1 
ATOM   4069 O O   . THR   A 1 501 ? 178.037 148.544 126.380 1.00 57.11  ? 527 THR   A O   1 
ATOM   4070 C CB  . THR   A 1 501 ? 180.315 149.833 124.526 1.00 55.36  ? 527 THR   A CB  1 
ATOM   4071 O OG1 . THR   A 1 501 ? 181.614 149.616 123.963 1.00 61.16  ? 527 THR   A OG1 1 
ATOM   4072 C CG2 . THR   A 1 501 ? 180.008 151.312 124.494 1.00 56.51  ? 527 THR   A CG2 1 
ATOM   4073 N N   . GLU   A 1 502 ? 178.643 150.543 127.229 1.00 46.33  ? 528 GLU   A N   1 
ATOM   4074 C CA  . GLU   A 1 502 ? 177.338 150.853 127.793 1.00 46.77  ? 528 GLU   A CA  1 
ATOM   4075 C C   . GLU   A 1 502 ? 177.012 152.318 127.547 1.00 45.20  ? 528 GLU   A C   1 
ATOM   4076 O O   . GLU   A 1 502 ? 177.909 153.161 127.425 1.00 50.44  ? 528 GLU   A O   1 
ATOM   4077 C CB  . GLU   A 1 502 ? 177.281 150.543 129.290 1.00 54.61  ? 528 GLU   A CB  1 
ATOM   4078 C CG  . GLU   A 1 502 ? 177.420 149.067 129.610 1.00 61.80  ? 528 GLU   A CG  1 
ATOM   4079 C CD  . GLU   A 1 502 ? 177.220 148.763 131.082 1.00 70.93  ? 528 GLU   A CD  1 
ATOM   4080 O OE1 . GLU   A 1 502 ? 176.743 149.653 131.818 1.00 71.37  ? 528 GLU   A OE1 1 
ATOM   4081 O OE2 . GLU   A 1 502 ? 177.539 147.633 131.505 1.00 79.03  ? 528 GLU   A OE2 1 
ATOM   4082 N N   . VAL   A 1 503 ? 175.711 152.610 127.488 1.00 40.05  ? 529 VAL   A N   1 
ATOM   4083 C CA  . VAL   A 1 503 ? 175.190 153.910 127.080 1.00 37.34  ? 529 VAL   A CA  1 
ATOM   4084 C C   . VAL   A 1 503 ? 174.156 154.382 128.093 1.00 39.14  ? 529 VAL   A C   1 
ATOM   4085 O O   . VAL   A 1 503 ? 173.361 153.584 128.599 1.00 47.06  ? 529 VAL   A O   1 
ATOM   4086 C CB  . VAL   A 1 503 ? 174.574 153.856 125.664 1.00 42.31  ? 529 VAL   A CB  1 
ATOM   4087 C CG1 . VAL   A 1 503 ? 173.416 152.859 125.595 1.00 49.66  ? 529 VAL   A CG1 1 
ATOM   4088 C CG2 . VAL   A 1 503 ? 174.117 155.234 125.226 1.00 43.04  ? 529 VAL   A CG2 1 
ATOM   4089 N N   . VAL   A 1 504 ? 174.172 155.682 128.389 1.00 37.70  ? 530 VAL   A N   1 
ATOM   4090 C CA  . VAL   A 1 504 ? 173.163 156.324 129.230 1.00 38.64  ? 530 VAL   A CA  1 
ATOM   4091 C C   . VAL   A 1 504 ? 172.709 157.610 128.551 1.00 43.32  ? 530 VAL   A C   1 
ATOM   4092 O O   . VAL   A 1 504 ? 173.542 158.438 128.169 1.00 46.21  ? 530 VAL   A O   1 
ATOM   4093 C CB  . VAL   A 1 504 ? 173.697 156.621 130.643 1.00 38.50  ? 530 VAL   A CB  1 
ATOM   4094 C CG1 . VAL   A 1 504 ? 172.666 157.394 131.448 1.00 40.04  ? 530 VAL   A CG1 1 
ATOM   4095 C CG2 . VAL   A 1 504 ? 174.069 155.329 131.350 1.00 42.75  ? 530 VAL   A CG2 1 
ATOM   4096 N N   . PHE   A 1 505 ? 171.395 157.784 128.419 1.00 40.88  ? 531 PHE   A N   1 
ATOM   4097 C CA  . PHE   A 1 505 ? 170.805 158.935 127.745 1.00 37.21  ? 531 PHE   A CA  1 
ATOM   4098 C C   . PHE   A 1 505 ? 170.263 159.926 128.766 1.00 39.01  ? 531 PHE   A C   1 
ATOM   4099 O O   . PHE   A 1 505 ? 169.703 159.526 129.791 1.00 44.93  ? 531 PHE   A O   1 
ATOM   4100 C CB  . PHE   A 1 505 ? 169.681 158.493 126.812 1.00 39.97  ? 531 PHE   A CB  1 
ATOM   4101 C CG  . PHE   A 1 505 ? 170.101 157.470 125.802 1.00 43.72  ? 531 PHE   A CG  1 
ATOM   4102 C CD1 . PHE   A 1 505 ? 170.993 157.796 124.800 1.00 44.15  ? 531 PHE   A CD1 1 
ATOM   4103 C CD2 . PHE   A 1 505 ? 169.601 156.187 125.849 1.00 44.33  ? 531 PHE   A CD2 1 
ATOM   4104 C CE1 . PHE   A 1 505 ? 171.380 156.859 123.872 1.00 45.25  ? 531 PHE   A CE1 1 
ATOM   4105 C CE2 . PHE   A 1 505 ? 169.985 155.252 124.922 1.00 44.43  ? 531 PHE   A CE2 1 
ATOM   4106 C CZ  . PHE   A 1 505 ? 170.873 155.588 123.933 1.00 45.54  ? 531 PHE   A CZ  1 
ATOM   4107 N N   . ILE   A 1 506 ? 170.427 161.220 128.484 1.00 37.50  ? 532 ILE   A N   1 
ATOM   4108 C CA  . ILE   A 1 506 ? 170.050 162.288 129.404 1.00 38.42  ? 532 ILE   A CA  1 
ATOM   4109 C C   . ILE   A 1 506 ? 169.347 163.388 128.623 1.00 39.74  ? 532 ILE   A C   1 
ATOM   4110 O O   . ILE   A 1 506 ? 169.741 163.716 127.499 1.00 44.90  ? 532 ILE   A O   1 
ATOM   4111 C CB  . ILE   A 1 506 ? 171.278 162.861 130.145 1.00 40.56  ? 532 ILE   A CB  1 
ATOM   4112 C CG1 . ILE   A 1 506 ? 171.938 161.806 131.043 1.00 40.55  ? 532 ILE   A CG1 1 
ATOM   4113 C CG2 . ILE   A 1 506 ? 170.902 164.091 130.952 1.00 42.86  ? 532 ILE   A CG2 1 
ATOM   4114 C CD1 . ILE   A 1 506 ? 171.109 161.348 132.238 1.00 39.79  ? 532 ILE   A CD1 1 
ATOM   4115 N N   . ALA   A 1 507 ? 168.299 163.952 129.226 1.00 40.12  ? 533 ALA   A N   1 
ATOM   4116 C CA  . ALA   A 1 507 ? 167.591 165.117 128.710 1.00 39.15  ? 533 ALA   A CA  1 
ATOM   4117 C C   . ALA   A 1 507 ? 167.489 166.141 129.827 1.00 43.37  ? 533 ALA   A C   1 
ATOM   4118 O O   . ALA   A 1 507 ? 166.981 165.827 130.907 1.00 46.97  ? 533 ALA   A O   1 
ATOM   4119 C CB  . ALA   A 1 507 ? 166.199 164.745 128.201 1.00 41.45  ? 533 ALA   A CB  1 
ATOM   4120 N N   . ASP   A 1 508 ? 167.957 167.362 129.564 1.00 48.72  ? 534 ASP   A N   1 
ATOM   4121 C CA  . ASP   A 1 508 ? 168.142 168.373 130.596 1.00 52.61  ? 534 ASP   A CA  1 
ATOM   4122 C C   . ASP   A 1 508 ? 167.433 169.666 130.213 1.00 52.33  ? 534 ASP   A C   1 
ATOM   4123 O O   . ASP   A 1 508 ? 167.309 170.003 129.031 1.00 54.90  ? 534 ASP   A O   1 
ATOM   4124 C CB  . ASP   A 1 508 ? 169.632 168.647 130.834 1.00 53.85  ? 534 ASP   A CB  1 
ATOM   4125 C CG  . ASP   A 1 508 ? 169.906 169.287 132.182 1.00 58.08  ? 534 ASP   A CG  1 
ATOM   4126 O OD1 . ASP   A 1 508 ? 168.944 169.583 132.921 1.00 56.95  ? 534 ASP   A OD1 1 
ATOM   4127 O OD2 . ASP   A 1 508 ? 171.093 169.496 132.505 1.00 54.92  ? 534 ASP   A OD2 1 
ATOM   4128 N N   . PHE   A 1 509 ? 166.988 170.388 131.238 1.00 50.18  ? 535 PHE   A N   1 
ATOM   4129 C CA  . PHE   A 1 509 ? 166.142 171.565 131.093 1.00 48.50  ? 535 PHE   A CA  1 
ATOM   4130 C C   . PHE   A 1 509 ? 166.971 172.820 130.837 1.00 48.83  ? 535 PHE   A C   1 
ATOM   4131 O O   . PHE   A 1 509 ? 168.187 172.829 131.033 1.00 54.30  ? 535 PHE   A O   1 
ATOM   4132 C CB  . PHE   A 1 509 ? 165.299 171.740 132.354 1.00 49.56  ? 535 PHE   A CB  1 
ATOM   4133 C CG  . PHE   A 1 509 ? 164.155 170.779 132.455 1.00 48.72  ? 535 PHE   A CG  1 
ATOM   4134 C CD1 . PHE   A 1 509 ? 163.016 170.960 131.701 1.00 47.74  ? 535 PHE   A CD1 1 
ATOM   4135 C CD2 . PHE   A 1 509 ? 164.218 169.699 133.310 1.00 49.32  ? 535 PHE   A CD2 1 
ATOM   4136 C CE1 . PHE   A 1 509 ? 161.966 170.079 131.793 1.00 46.18  ? 535 PHE   A CE1 1 
ATOM   4137 C CE2 . PHE   A 1 509 ? 163.170 168.818 133.405 1.00 44.61  ? 535 PHE   A CE2 1 
ATOM   4138 C CZ  . PHE   A 1 509 ? 162.043 169.008 132.645 1.00 44.61  ? 535 PHE   A CZ  1 
ATOM   4139 N N   . PRO   A 1 510 ? 166.338 173.910 130.392 1.00 47.21  ? 536 PRO   A N   1 
ATOM   4140 C CA  . PRO   A 1 510 ? 167.085 175.160 130.188 1.00 46.56  ? 536 PRO   A CA  1 
ATOM   4141 C C   . PRO   A 1 510 ? 167.507 175.790 131.507 1.00 45.16  ? 536 PRO   A C   1 
ATOM   4142 O O   . PRO   A 1 510 ? 166.701 175.936 132.426 1.00 45.52  ? 536 PRO   A O   1 
ATOM   4143 C CB  . PRO   A 1 510 ? 166.087 176.049 129.438 1.00 52.34  ? 536 PRO   A CB  1 
ATOM   4144 C CG  . PRO   A 1 510 ? 164.759 175.504 129.788 1.00 57.49  ? 536 PRO   A CG  1 
ATOM   4145 C CD  . PRO   A 1 510 ? 164.963 174.027 129.874 1.00 54.04  ? 536 PRO   A CD  1 
ATOM   4146 N N   . GLY   A 1 511 ? 168.782 176.162 131.587 1.00 45.35  ? 537 GLY   A N   1 
ATOM   4147 C CA  . GLY   A 1 511 ? 169.324 176.839 132.749 1.00 46.69  ? 537 GLY   A CA  1 
ATOM   4148 C C   . GLY   A 1 511 ? 170.096 175.926 133.678 1.00 46.20  ? 537 GLY   A C   1 
ATOM   4149 O O   . GLY   A 1 511 ? 171.111 176.328 134.251 1.00 46.57  ? 537 GLY   A O   1 
ATOM   4150 N N   . LEU   A 1 512 ? 169.626 174.693 133.828 1.00 45.07  ? 538 LEU   A N   1 
ATOM   4151 C CA  . LEU   A 1 512 ? 170.191 173.762 134.789 1.00 43.51  ? 538 LEU   A CA  1 
ATOM   4152 C C   . LEU   A 1 512 ? 171.503 173.179 134.266 1.00 46.77  ? 538 LEU   A C   1 
ATOM   4153 O O   . LEU   A 1 512 ? 171.871 173.348 133.102 1.00 49.12  ? 538 LEU   A O   1 
ATOM   4154 C CB  . LEU   A 1 512 ? 169.189 172.647 135.096 1.00 46.81  ? 538 LEU   A CB  1 
ATOM   4155 C CG  . LEU   A 1 512 ? 168.045 172.970 136.064 1.00 49.88  ? 538 LEU   A CG  1 
ATOM   4156 C CD1 . LEU   A 1 512 ? 167.139 174.071 135.540 1.00 50.74  ? 538 LEU   A CD1 1 
ATOM   4157 C CD2 . LEU   A 1 512 ? 167.238 171.720 136.341 1.00 48.22  ? 538 LEU   A CD2 1 
ATOM   4158 N N   . HIS   A 1 513 ? 172.221 172.493 135.155 1.00 50.15  ? 539 HIS   A N   1 
ATOM   4159 C CA  . HIS   A 1 513 ? 173.478 171.846 134.805 1.00 46.98  ? 539 HIS   A CA  1 
ATOM   4160 C C   . HIS   A 1 513 ? 173.639 170.583 135.635 1.00 48.77  ? 539 HIS   A C   1 
ATOM   4161 O O   . HIS   A 1 513 ? 172.995 170.415 136.674 1.00 53.04  ? 539 HIS   A O   1 
ATOM   4162 C CB  . HIS   A 1 513 ? 174.674 172.772 135.029 1.00 45.47  ? 539 HIS   A CB  1 
ATOM   4163 C CG  . HIS   A 1 513 ? 175.017 172.974 136.471 1.00 43.10  ? 539 HIS   A CG  1 
ATOM   4164 N ND1 . HIS   A 1 513 ? 175.848 172.123 137.165 1.00 44.28  ? 539 HIS   A ND1 1 
ATOM   4165 C CD2 . HIS   A 1 513 ? 174.639 173.930 137.351 1.00 43.18  ? 539 HIS   A CD2 1 
ATOM   4166 C CE1 . HIS   A 1 513 ? 175.968 172.546 138.410 1.00 48.04  ? 539 HIS   A CE1 1 
ATOM   4167 N NE2 . HIS   A 1 513 ? 175.244 173.641 138.549 1.00 47.83  ? 539 HIS   A NE2 1 
ATOM   4168 N N   . LEU   A 1 514 ? 174.514 169.696 135.162 1.00 46.11  ? 540 LEU   A N   1 
ATOM   4169 C CA  . LEU   A 1 514 ? 174.836 168.448 135.847 1.00 43.32  ? 540 LEU   A CA  1 
ATOM   4170 C C   . LEU   A 1 514 ? 176.339 168.352 136.053 1.00 43.15  ? 540 LEU   A C   1 
ATOM   4171 O O   . LEU   A 1 514 ? 177.106 168.461 135.092 1.00 48.55  ? 540 LEU   A O   1 
ATOM   4172 C CB  . LEU   A 1 514 ? 174.329 167.242 135.051 1.00 40.52  ? 540 LEU   A CB  1 
ATOM   4173 C CG  . LEU   A 1 514 ? 174.615 165.839 135.585 1.00 39.49  ? 540 LEU   A CG  1 
ATOM   4174 C CD1 . LEU   A 1 514 ? 173.929 165.624 136.926 1.00 44.61  ? 540 LEU   A CD1 1 
ATOM   4175 C CD2 . LEU   A 1 514 ? 174.177 164.797 134.582 1.00 37.70  ? 540 LEU   A CD2 1 
ATOM   4176 N N   . GLU   A 1 515 ? 176.751 168.126 137.299 1.00 40.48  ? 541 GLU   A N   1 
ATOM   4177 C CA  . GLU   A 1 515 ? 178.151 167.959 137.676 1.00 41.47  ? 541 GLU   A CA  1 
ATOM   4178 C C   . GLU   A 1 515 ? 178.385 166.487 137.975 1.00 41.11  ? 541 GLU   A C   1 
ATOM   4179 O O   . GLU   A 1 515 ? 177.679 165.908 138.806 1.00 48.29  ? 541 GLU   A O   1 
ATOM   4180 C CB  . GLU   A 1 515 ? 178.488 168.817 138.895 1.00 44.92  ? 541 GLU   A CB  1 
ATOM   4181 C CG  . GLU   A 1 515 ? 179.947 168.782 139.315 1.00 49.05  ? 541 GLU   A CG  1 
ATOM   4182 C CD  . GLU   A 1 515 ? 180.227 169.672 140.506 1.00 54.85  ? 541 GLU   A CD  1 
ATOM   4183 O OE1 . GLU   A 1 515 ? 179.259 170.154 141.129 1.00 57.33  ? 541 GLU   A OE1 1 
ATOM   4184 O OE2 . GLU   A 1 515 ? 181.414 169.895 140.820 1.00 53.01  ? 541 GLU   A OE2 1 
ATOM   4185 N N   . ASN   A 1 516 ? 179.372 165.883 137.306 1.00 37.00  ? 542 ASN   A N   1 
ATOM   4186 C CA  . ASN   A 1 516 ? 179.594 164.447 137.384 1.00 39.54  ? 542 ASN   A CA  1 
ATOM   4187 C C   . ASN   A 1 516 ? 181.074 164.141 137.563 1.00 44.19  ? 542 ASN   A C   1 
ATOM   4188 O O   . ASN   A 1 516 ? 181.941 164.923 137.163 1.00 48.90  ? 542 ASN   A O   1 
ATOM   4189 C CB  . ASN   A 1 516 ? 179.062 163.748 136.136 1.00 39.18  ? 542 ASN   A CB  1 
ATOM   4190 C CG  . ASN   A 1 516 ? 178.916 162.256 136.319 1.00 47.49  ? 542 ASN   A CG  1 
ATOM   4191 O OD1 . ASN   A 1 516 ? 178.897 161.749 137.441 1.00 57.49  ? 542 ASN   A OD1 1 
ATOM   4192 N ND2 . ASN   A 1 516 ? 178.810 161.538 135.212 1.00 47.30  ? 542 ASN   A ND2 1 
ATOM   4193 N N   . PHE   A 1 517 ? 181.349 162.991 138.182 1.00 42.19  ? 543 PHE   A N   1 
ATOM   4194 C CA  . PHE   A 1 517 ? 182.704 162.533 138.479 1.00 39.86  ? 543 PHE   A CA  1 
ATOM   4195 C C   . PHE   A 1 517 ? 182.884 161.152 137.872 1.00 42.68  ? 543 PHE   A C   1 
ATOM   4196 O O   . PHE   A 1 517 ? 182.214 160.199 138.281 1.00 46.08  ? 543 PHE   A O   1 
ATOM   4197 C CB  . PHE   A 1 517 ? 182.964 162.500 139.986 1.00 40.45  ? 543 PHE   A CB  1 
ATOM   4198 C CG  . PHE   A 1 517 ? 184.324 161.988 140.360 1.00 44.25  ? 543 PHE   A CG  1 
ATOM   4199 C CD1 . PHE   A 1 517 ? 185.417 162.832 140.377 1.00 49.97  ? 543 PHE   A CD1 1 
ATOM   4200 C CD2 . PHE   A 1 517 ? 184.508 160.666 140.709 1.00 38.89  ? 543 PHE   A CD2 1 
ATOM   4201 C CE1 . PHE   A 1 517 ? 186.663 162.363 140.725 1.00 44.54  ? 543 PHE   A CE1 1 
ATOM   4202 C CE2 . PHE   A 1 517 ? 185.752 160.195 141.054 1.00 37.85  ? 543 PHE   A CE2 1 
ATOM   4203 C CZ  . PHE   A 1 517 ? 186.829 161.043 141.063 1.00 38.84  ? 543 PHE   A CZ  1 
ATOM   4204 N N   . VAL   A 1 518 ? 183.786 161.045 136.905 1.00 44.96  ? 544 VAL   A N   1 
ATOM   4205 C CA  . VAL   A 1 518 ? 184.070 159.772 136.253 1.00 43.10  ? 544 VAL   A CA  1 
ATOM   4206 C C   . VAL   A 1 518 ? 185.100 159.022 137.085 1.00 49.35  ? 544 VAL   A C   1 
ATOM   4207 O O   . VAL   A 1 518 ? 186.150 159.571 137.434 1.00 53.77  ? 544 VAL   A O   1 
ATOM   4208 C CB  . VAL   A 1 518 ? 184.570 159.993 134.816 1.00 44.77  ? 544 VAL   A CB  1 
ATOM   4209 C CG1 . VAL   A 1 518 ? 184.482 158.702 134.019 1.00 48.29  ? 544 VAL   A CG1 1 
ATOM   4210 C CG2 . VAL   A 1 518 ? 183.787 161.102 134.130 1.00 45.97  ? 544 VAL   A CG2 1 
ATOM   4211 N N   . SER   A 1 519 ? 184.803 157.767 137.407 1.00 51.45  ? 545 SER   A N   1 
ATOM   4212 C CA  . SER   A 1 519 ? 185.707 156.983 138.230 1.00 48.64  ? 545 SER   A CA  1 
ATOM   4213 C C   . SER   A 1 519 ? 186.982 156.656 137.462 1.00 52.29  ? 545 SER   A C   1 
ATOM   4214 O O   . SER   A 1 519 ? 187.034 156.714 136.231 1.00 58.88  ? 545 SER   A O   1 
ATOM   4215 C CB  . SER   A 1 519 ? 185.029 155.696 138.695 1.00 51.81  ? 545 SER   A CB  1 
ATOM   4216 O OG  . SER   A 1 519 ? 184.594 154.922 137.592 1.00 55.44  ? 545 SER   A OG  1 
ATOM   4217 N N   . GLU   A 1 520 ? 188.029 156.314 138.215 1.00 55.46  ? 546 GLU   A N   1 
ATOM   4218 C CA  . GLU   A 1 520 ? 189.310 155.996 137.595 1.00 56.43  ? 546 GLU   A CA  1 
ATOM   4219 C C   . GLU   A 1 520 ? 189.221 154.741 136.741 1.00 55.56  ? 546 GLU   A C   1 
ATOM   4220 O O   . GLU   A 1 520 ? 189.963 154.604 135.763 1.00 54.76  ? 546 GLU   A O   1 
ATOM   4221 C CB  . GLU   A 1 520 ? 190.385 155.831 138.666 1.00 59.19  ? 546 GLU   A CB  1 
ATOM   4222 C CG  . GLU   A 1 520 ? 190.617 157.076 139.507 1.00 65.18  ? 546 GLU   A CG  1 
ATOM   4223 C CD  . GLU   A 1 520 ? 191.688 156.877 140.561 1.00 73.98  ? 546 GLU   A CD  1 
ATOM   4224 O OE1 . GLU   A 1 520 ? 192.214 155.750 140.671 1.00 76.38  ? 546 GLU   A OE1 1 
ATOM   4225 O OE2 . GLU   A 1 520 ? 192.005 157.848 141.280 1.00 76.72  ? 546 GLU   A OE2 1 
ATOM   4226 N N   . ASP   A 1 521 ? 188.329 153.816 137.096 1.00 55.32  ? 547 ASP   A N   1 
ATOM   4227 C CA  . ASP   A 1 521 ? 188.178 152.597 136.312 1.00 55.95  ? 547 ASP   A CA  1 
ATOM   4228 C C   . ASP   A 1 521 ? 187.616 152.892 134.926 1.00 57.28  ? 547 ASP   A C   1 
ATOM   4229 O O   . ASP   A 1 521 ? 188.062 152.308 133.933 1.00 60.16  ? 547 ASP   A O   1 
ATOM   4230 C CB  . ASP   A 1 521 ? 187.276 151.614 137.054 1.00 61.19  ? 547 ASP   A CB  1 
ATOM   4231 C CG  . ASP   A 1 521 ? 187.773 151.307 138.452 1.00 70.34  ? 547 ASP   A CG  1 
ATOM   4232 O OD1 . ASP   A 1 521 ? 189.005 151.309 138.659 1.00 71.68  ? 547 ASP   A OD1 1 
ATOM   4233 O OD2 . ASP   A 1 521 ? 186.933 151.068 139.345 1.00 71.84  ? 547 ASP   A OD2 1 
ATOM   4234 N N   . LEU   A 1 522 ? 186.641 153.797 134.837 1.00 56.89  ? 548 LEU   A N   1 
ATOM   4235 C CA  . LEU   A 1 522 ? 185.922 154.049 133.587 1.00 48.64  ? 548 LEU   A CA  1 
ATOM   4236 C C   . LEU   A 1 522 ? 186.773 154.927 132.668 1.00 51.28  ? 548 LEU   A C   1 
ATOM   4237 O O   . LEU   A 1 522 ? 186.499 156.104 132.429 1.00 55.37  ? 548 LEU   A O   1 
ATOM   4238 C CB  . LEU   A 1 522 ? 184.565 154.682 133.868 1.00 45.83  ? 548 LEU   A CB  1 
ATOM   4239 C CG  . LEU   A 1 522 ? 183.395 153.727 134.094 1.00 49.97  ? 548 LEU   A CG  1 
ATOM   4240 C CD1 . LEU   A 1 522 ? 183.719 152.675 135.143 1.00 57.56  ? 548 LEU   A CD1 1 
ATOM   4241 C CD2 . LEU   A 1 522 ? 182.160 154.507 134.488 1.00 52.39  ? 548 LEU   A CD2 1 
ATOM   4242 N N   . GLY   A 1 523 ? 187.838 154.324 132.150 1.00 52.34  ? 549 GLY   A N   1 
ATOM   4243 C CA  . GLY   A 1 523 ? 188.566 154.930 131.062 1.00 52.26  ? 549 GLY   A CA  1 
ATOM   4244 C C   . GLY   A 1 523 ? 187.818 154.793 129.752 1.00 56.84  ? 549 GLY   A C   1 
ATOM   4245 O O   . GLY   A 1 523 ? 186.945 153.941 129.592 1.00 59.14  ? 549 GLY   A O   1 
ATOM   4246 N N   . ASN   A 1 524 ? 188.169 155.650 128.798 1.00 57.27  ? 550 ASN   A N   1 
ATOM   4247 C CA  . ASN   A 1 524 ? 187.540 155.660 127.480 1.00 58.27  ? 550 ASN   A CA  1 
ATOM   4248 C C   . ASN   A 1 524 ? 186.038 155.936 127.590 1.00 53.75  ? 550 ASN   A C   1 
ATOM   4249 O O   . ASN   A 1 524 ? 185.197 155.145 127.162 1.00 55.90  ? 550 ASN   A O   1 
ATOM   4250 C CB  . ASN   A 1 524 ? 187.806 154.341 126.747 1.00 59.40  ? 550 ASN   A CB  1 
ATOM   4251 C CG  . ASN   A 1 524 ? 187.251 154.335 125.342 1.00 67.44  ? 550 ASN   A CG  1 
ATOM   4252 O OD1 . ASN   A 1 524 ? 187.900 154.802 124.406 1.00 70.24  ? 550 ASN   A OD1 1 
ATOM   4253 N ND2 . ASN   A 1 524 ? 186.046 153.807 125.184 1.00 70.44  ? 550 ASN   A ND2 1 
ATOM   4254 N N   . THR   A 1 525 ? 185.722 157.087 128.177 1.00 50.36  ? 551 THR   A N   1 
ATOM   4255 C CA  . THR   A 1 525 ? 184.361 157.602 128.279 1.00 50.34  ? 551 THR   A CA  1 
ATOM   4256 C C   . THR   A 1 525 ? 184.217 158.805 127.356 1.00 54.93  ? 551 THR   A C   1 
ATOM   4257 O O   . THR   A 1 525 ? 185.098 159.671 127.325 1.00 60.41  ? 551 THR   A O   1 
ATOM   4258 C CB  . THR   A 1 525 ? 184.034 158.000 129.719 1.00 51.71  ? 551 THR   A CB  1 
ATOM   4259 O OG1 . THR   A 1 525 ? 184.056 156.839 130.557 1.00 56.05  ? 551 THR   A OG1 1 
ATOM   4260 C CG2 . THR   A 1 525 ? 182.663 158.653 129.799 1.00 52.51  ? 551 THR   A CG2 1 
ATOM   4261 N N   . SER   A 1 526 ? 183.111 158.858 126.611 1.00 48.05  ? 552 SER   A N   1 
ATOM   4262 C CA  . SER   A 1 526 ? 182.876 159.895 125.614 1.00 46.73  ? 552 SER   A CA  1 
ATOM   4263 C C   . SER   A 1 526 ? 181.456 160.432 125.728 1.00 48.28  ? 552 SER   A C   1 
ATOM   4264 O O   . SER   A 1 526 ? 180.542 159.723 126.153 1.00 50.93  ? 552 SER   A O   1 
ATOM   4265 C CB  . SER   A 1 526 ? 183.112 159.363 124.202 1.00 53.20  ? 552 SER   A CB  1 
ATOM   4266 O OG  . SER   A 1 526 ? 182.239 158.286 123.914 1.00 58.71  ? 552 SER   A OG  1 
ATOM   4267 N N   . ILE   A 1 527 ? 181.287 161.697 125.339 1.00 48.36  ? 553 ILE   A N   1 
ATOM   4268 C CA  . ILE   A 1 527 ? 180.006 162.400 125.389 1.00 45.65  ? 553 ILE   A CA  1 
ATOM   4269 C C   . ILE   A 1 527 ? 179.676 162.913 123.994 1.00 51.75  ? 553 ILE   A C   1 
ATOM   4270 O O   . ILE   A 1 527 ? 180.511 163.558 123.351 1.00 57.39  ? 553 ILE   A O   1 
ATOM   4271 C CB  . ILE   A 1 527 ? 180.020 163.555 126.411 1.00 41.74  ? 553 ILE   A CB  1 
ATOM   4272 C CG1 . ILE   A 1 527 ? 178.671 164.279 126.421 1.00 41.34  ? 553 ILE   A CG1 1 
ATOM   4273 C CG2 . ILE   A 1 527 ? 181.148 164.551 126.126 1.00 47.99  ? 553 ILE   A CG2 1 
ATOM   4274 C CD1 . ILE   A 1 527 ? 178.473 165.185 127.611 1.00 47.93  ? 553 ILE   A CD1 1 
ATOM   4275 N N   . GLN   A 1 528 ? 178.457 162.626 123.532 1.00 48.52  ? 554 GLN   A N   1 
ATOM   4276 C CA  . GLN   A 1 528 ? 177.960 163.053 122.231 1.00 43.31  ? 554 GLN   A CA  1 
ATOM   4277 C C   . GLN   A 1 528 ? 176.623 163.754 122.414 1.00 40.88  ? 554 GLN   A C   1 
ATOM   4278 O O   . GLN   A 1 528 ? 175.829 163.386 123.282 1.00 46.98  ? 554 GLN   A O   1 
ATOM   4279 C CB  . GLN   A 1 528 ? 177.805 161.859 121.279 1.00 48.29  ? 554 GLN   A CB  1 
ATOM   4280 C CG  . GLN   A 1 528 ? 177.251 162.198 119.905 1.00 52.52  ? 554 GLN   A CG  1 
ATOM   4281 C CD  . GLN   A 1 528 ? 177.296 161.020 118.953 1.00 55.96  ? 554 GLN   A CD  1 
ATOM   4282 O OE1 . GLN   A 1 528 ? 177.869 159.978 119.263 1.00 55.58  ? 554 GLN   A OE1 1 
ATOM   4283 N NE2 . GLN   A 1 528 ? 176.686 161.180 117.786 1.00 56.83  ? 554 GLN   A NE2 1 
ATOM   4284 N N   . LEU   A 1 529 ? 176.382 164.766 121.587 1.00 41.65  ? 555 LEU   A N   1 
ATOM   4285 C CA  . LEU   A 1 529 ? 175.179 165.586 121.665 1.00 42.26  ? 555 LEU   A CA  1 
ATOM   4286 C C   . LEU   A 1 529 ? 174.192 165.159 120.588 1.00 48.31  ? 555 LEU   A C   1 
ATOM   4287 O O   . LEU   A 1 529 ? 174.562 165.037 119.415 1.00 57.04  ? 555 LEU   A O   1 
ATOM   4288 C CB  . LEU   A 1 529 ? 175.534 167.065 121.508 1.00 40.62  ? 555 LEU   A CB  1 
ATOM   4289 C CG  . LEU   A 1 529 ? 174.398 168.083 121.463 1.00 40.71  ? 555 LEU   A CG  1 
ATOM   4290 C CD1 . LEU   A 1 529 ? 173.504 167.962 122.677 1.00 43.84  ? 555 LEU   A CD1 1 
ATOM   4291 C CD2 . LEU   A 1 529 ? 174.964 169.484 121.366 1.00 45.91  ? 555 LEU   A CD2 1 
ATOM   4292 N N   . LEU   A 1 530 ? 172.938 164.939 120.988 1.00 45.32  ? 556 LEU   A N   1 
ATOM   4293 C CA  . LEU   A 1 530 ? 171.880 164.504 120.082 1.00 40.67  ? 556 LEU   A CA  1 
ATOM   4294 C C   . LEU   A 1 530 ? 170.956 165.635 119.657 1.00 46.91  ? 556 LEU   A C   1 
ATOM   4295 O O   . LEU   A 1 530 ? 170.567 165.700 118.489 1.00 51.43  ? 556 LEU   A O   1 
ATOM   4296 C CB  . LEU   A 1 530 ? 171.043 163.401 120.732 1.00 39.00  ? 556 LEU   A CB  1 
ATOM   4297 C CG  . LEU   A 1 530 ? 171.760 162.116 121.137 1.00 43.54  ? 556 LEU   A CG  1 
ATOM   4298 C CD1 . LEU   A 1 530 ? 170.778 161.164 121.782 1.00 47.67  ? 556 LEU   A CD1 1 
ATOM   4299 C CD2 . LEU   A 1 530 ? 172.428 161.458 119.948 1.00 45.43  ? 556 LEU   A CD2 1 
ATOM   4300 N N   . GLN   A 1 531 ? 170.587 166.520 120.578 1.00 52.01  ? 557 GLN   A N   1 
ATOM   4301 C CA  . GLN   A 1 531 ? 169.711 167.636 120.246 1.00 49.70  ? 557 GLN   A CA  1 
ATOM   4302 C C   . GLN   A 1 531 ? 169.988 168.780 121.206 1.00 53.43  ? 557 GLN   A C   1 
ATOM   4303 O O   . GLN   A 1 531 ? 170.250 168.549 122.388 1.00 59.21  ? 557 GLN   A O   1 
ATOM   4304 C CB  . GLN   A 1 531 ? 168.235 167.228 120.316 1.00 50.38  ? 557 GLN   A CB  1 
ATOM   4305 C CG  . GLN   A 1 531 ? 167.247 168.384 120.154 1.00 52.96  ? 557 GLN   A CG  1 
ATOM   4306 C CD  . GLN   A 1 531 ? 165.815 167.918 119.999 1.00 57.37  ? 557 GLN   A CD  1 
ATOM   4307 O OE1 . GLN   A 1 531 ? 165.555 166.813 119.527 1.00 55.47  ? 557 GLN   A OE1 1 
ATOM   4308 N NE2 . GLN   A 1 531 ? 164.875 168.761 120.402 1.00 54.92  ? 557 GLN   A NE2 1 
ATOM   4309 N N   . GLY   A 1 532 ? 169.916 170.001 120.695 1.00 49.94  ? 558 GLY   A N   1 
ATOM   4310 C CA  . GLY   A 1 532 ? 170.064 171.184 121.514 1.00 51.95  ? 558 GLY   A CA  1 
ATOM   4311 C C   . GLY   A 1 532 ? 171.470 171.744 121.491 1.00 52.09  ? 558 GLY   A C   1 
ATOM   4312 O O   . GLY   A 1 532 ? 172.249 171.533 120.560 1.00 56.99  ? 558 GLY   A O   1 
ATOM   4313 N N   . GLU   A 1 533 ? 171.791 172.484 122.552 1.00 50.24  ? 559 GLU   A N   1 
ATOM   4314 C CA  . GLU   A 1 533 ? 173.097 173.109 122.706 1.00 54.80  ? 559 GLU   A CA  1 
ATOM   4315 C C   . GLU   A 1 533 ? 173.530 173.003 124.159 1.00 54.53  ? 559 GLU   A C   1 
ATOM   4316 O O   . GLU   A 1 533 ? 172.785 173.400 125.060 1.00 54.33  ? 559 GLU   A O   1 
ATOM   4317 C CB  . GLU   A 1 533 ? 173.056 174.577 122.269 1.00 56.01  ? 559 GLU   A CB  1 
ATOM   4318 C CG  . GLU   A 1 533 ? 174.417 175.250 122.201 1.00 62.16  ? 559 GLU   A CG  1 
ATOM   4319 C CD  . GLU   A 1 533 ? 174.325 176.704 121.783 1.00 70.06  ? 559 GLU   A CD  1 
ATOM   4320 O OE1 . GLU   A 1 533 ? 173.194 177.194 121.583 1.00 69.62  ? 559 GLU   A OE1 1 
ATOM   4321 O OE2 . GLU   A 1 533 ? 175.382 177.357 121.656 1.00 72.16  ? 559 GLU   A OE2 1 
ATOM   4322 N N   . VAL   A 1 534 ? 174.733 172.467 124.380 1.00 48.98  ? 560 VAL   A N   1 
ATOM   4323 C CA  . VAL   A 1 534 ? 175.312 172.323 125.707 1.00 42.65  ? 560 VAL   A CA  1 
ATOM   4324 C C   . VAL   A 1 534 ? 176.751 172.814 125.671 1.00 44.81  ? 560 VAL   A C   1 
ATOM   4325 O O   . VAL   A 1 534 ? 177.354 172.977 124.609 1.00 51.11  ? 560 VAL   A O   1 
ATOM   4326 C CB  . VAL   A 1 534 ? 175.258 170.870 126.230 1.00 42.59  ? 560 VAL   A CB  1 
ATOM   4327 C CG1 . VAL   A 1 534 ? 173.823 170.436 126.428 1.00 46.04  ? 560 VAL   A CG1 1 
ATOM   4328 C CG2 . VAL   A 1 534 ? 175.979 169.909 125.293 1.00 44.72  ? 560 VAL   A CG2 1 
ATOM   4329 N N   . THR   A 1 535 ? 177.287 173.073 126.861 1.00 46.22  ? 561 THR   A N   1 
ATOM   4330 C CA  . THR   A 1 535 ? 178.692 173.413 127.043 1.00 49.16  ? 561 THR   A CA  1 
ATOM   4331 C C   . THR   A 1 535 ? 179.269 172.521 128.130 1.00 48.89  ? 561 THR   A C   1 
ATOM   4332 O O   . THR   A 1 535 ? 178.691 172.408 129.215 1.00 55.26  ? 561 THR   A O   1 
ATOM   4333 C CB  . THR   A 1 535 ? 178.875 174.886 127.414 1.00 50.22  ? 561 THR   A CB  1 
ATOM   4334 O OG1 . THR   A 1 535 ? 178.409 175.110 128.747 1.00 54.14  ? 561 THR   A OG1 1 
ATOM   4335 C CG2 . THR   A 1 535 ? 178.103 175.776 126.457 1.00 51.27  ? 561 THR   A CG2 1 
ATOM   4336 N N   . VAL   A 1 536 ? 180.398 171.883 127.832 1.00 42.96  ? 562 VAL   A N   1 
ATOM   4337 C CA  . VAL   A 1 536 ? 181.036 170.926 128.728 1.00 44.49  ? 562 VAL   A CA  1 
ATOM   4338 C C   . VAL   A 1 536 ? 182.274 171.592 129.302 1.00 53.23  ? 562 VAL   A C   1 
ATOM   4339 O O   . VAL   A 1 536 ? 183.145 172.045 128.548 1.00 58.81  ? 562 VAL   A O   1 
ATOM   4340 C CB  . VAL   A 1 536 ? 181.399 169.621 128.004 1.00 47.73  ? 562 VAL   A CB  1 
ATOM   4341 C CG1 . VAL   A 1 536 ? 181.955 168.603 128.987 1.00 48.95  ? 562 VAL   A CG1 1 
ATOM   4342 C CG2 . VAL   A 1 536 ? 180.185 169.064 127.270 1.00 50.24  ? 562 VAL   A CG2 1 
ATOM   4343 N N   . GLU   A 1 537 ? 182.352 171.638 130.630 1.00 55.07  ? 563 GLU   A N   1 
ATOM   4344 C CA  . GLU   A 1 537 ? 183.417 172.303 131.369 1.00 51.38  ? 563 GLU   A CA  1 
ATOM   4345 C C   . GLU   A 1 537 ? 184.234 171.259 132.113 1.00 53.15  ? 563 GLU   A C   1 
ATOM   4346 O O   . GLU   A 1 537 ? 183.681 170.471 132.889 1.00 56.67  ? 563 GLU   A O   1 
ATOM   4347 C CB  . GLU   A 1 537 ? 182.836 173.323 132.348 1.00 51.90  ? 563 GLU   A CB  1 
ATOM   4348 C CG  . GLU   A 1 537 ? 183.841 173.923 133.327 1.00 57.68  ? 563 GLU   A CG  1 
ATOM   4349 C CD  . GLU   A 1 537 ? 183.263 175.065 134.136 1.00 62.37  ? 563 GLU   A CD  1 
ATOM   4350 O OE1 . GLU   A 1 537 ? 182.094 175.435 133.900 1.00 65.33  ? 563 GLU   A OE1 1 
ATOM   4351 O OE2 . GLU   A 1 537 ? 183.978 175.594 135.012 1.00 62.32  ? 563 GLU   A OE2 1 
ATOM   4352 N N   . LEU   A 1 538 ? 185.544 171.261 131.875 1.00 56.40  ? 564 LEU   A N   1 
ATOM   4353 C CA  . LEU   A 1 538 ? 186.498 170.533 132.698 1.00 59.14  ? 564 LEU   A CA  1 
ATOM   4354 C C   . LEU   A 1 538 ? 187.060 171.498 133.733 1.00 63.64  ? 564 LEU   A C   1 
ATOM   4355 O O   . LEU   A 1 538 ? 187.584 172.564 133.377 1.00 70.96  ? 564 LEU   A O   1 
ATOM   4356 C CB  . LEU   A 1 538 ? 187.619 169.943 131.847 1.00 62.15  ? 564 LEU   A CB  1 
ATOM   4357 C CG  . LEU   A 1 538 ? 187.208 169.043 130.684 1.00 62.89  ? 564 LEU   A CG  1 
ATOM   4358 C CD1 . LEU   A 1 538 ? 188.441 168.564 129.947 1.00 63.39  ? 564 LEU   A CD1 1 
ATOM   4359 C CD2 . LEU   A 1 538 ? 186.386 167.864 131.169 1.00 60.96  ? 564 LEU   A CD2 1 
ATOM   4360 N N   . VAL   A 1 539 ? 186.946 171.123 135.008 1.00 58.61  ? 565 VAL   A N   1 
ATOM   4361 C CA  . VAL   A 1 539 ? 187.270 172.035 136.100 1.00 61.43  ? 565 VAL   A CA  1 
ATOM   4362 C C   . VAL   A 1 539 ? 188.723 171.940 136.553 1.00 62.27  ? 565 VAL   A C   1 
ATOM   4363 O O   . VAL   A 1 539 ? 189.188 172.826 137.285 1.00 66.85  ? 565 VAL   A O   1 
ATOM   4364 C CB  . VAL   A 1 539 ? 186.336 171.802 137.304 1.00 58.88  ? 565 VAL   A CB  1 
ATOM   4365 C CG1 . VAL   A 1 539 ? 184.881 171.908 136.879 1.00 58.86  ? 565 VAL   A CG1 1 
ATOM   4366 C CG2 . VAL   A 1 539 ? 186.599 170.459 137.969 1.00 54.65  ? 565 VAL   A CG2 1 
ATOM   4367 N N   . ALA   A 1 540 ? 189.447 170.893 136.156 1.00 62.22  ? 566 ALA   A N   1 
ATOM   4368 C CA  . ALA   A 1 540 ? 190.850 170.785 136.542 1.00 66.92  ? 566 ALA   A CA  1 
ATOM   4369 C C   . ALA   A 1 540 ? 191.670 171.932 135.966 1.00 67.18  ? 566 ALA   A C   1 
ATOM   4370 O O   . ALA   A 1 540 ? 192.542 172.481 136.650 1.00 67.58  ? 566 ALA   A O   1 
ATOM   4371 C CB  . ALA   A 1 540 ? 191.415 169.439 136.091 1.00 65.91  ? 566 ALA   A CB  1 
ATOM   4372 N N   . GLU   A 1 541 ? 191.402 172.308 134.713 1.00 66.77  ? 567 GLU   A N   1 
ATOM   4373 C CA  . GLU   A 1 541 ? 192.076 173.424 134.057 1.00 68.61  ? 567 GLU   A CA  1 
ATOM   4374 C C   . GLU   A 1 541 ? 191.126 174.561 133.695 1.00 71.04  ? 567 GLU   A C   1 
ATOM   4375 O O   . GLU   A 1 541 ? 191.557 175.521 133.045 1.00 74.16  ? 567 GLU   A O   1 
ATOM   4376 C CB  . GLU   A 1 541 ? 192.811 172.943 132.800 1.00 69.59  ? 567 GLU   A CB  1 
ATOM   4377 C CG  . GLU   A 1 541 ? 191.988 172.068 131.872 1.00 75.20  ? 567 GLU   A CG  1 
ATOM   4378 C CD  . GLU   A 1 541 ? 192.161 170.586 132.146 1.00 80.96  ? 567 GLU   A CD  1 
ATOM   4379 O OE1 . GLU   A 1 541 ? 192.538 170.223 133.279 1.00 80.95  ? 567 GLU   A OE1 1 
ATOM   4380 O OE2 . GLU   A 1 541 ? 191.928 169.780 131.221 1.00 83.97  ? 567 GLU   A OE2 1 
ATOM   4381 N N   . GLN   A 1 542 ? 189.858 174.495 134.111 1.00 69.17  ? 568 GLN   A N   1 
ATOM   4382 C CA  . GLN   A 1 542 ? 188.887 175.568 133.887 1.00 67.77  ? 568 GLN   A CA  1 
ATOM   4383 C C   . GLN   A 1 542 ? 188.749 175.880 132.396 1.00 67.35  ? 568 GLN   A C   1 
ATOM   4384 O O   . GLN   A 1 542 ? 189.051 176.982 131.937 1.00 67.96  ? 568 GLN   A O   1 
ATOM   4385 C CB  . GLN   A 1 542 ? 189.271 176.829 134.671 1.00 68.58  ? 568 GLN   A CB  1 
ATOM   4386 C CG  . GLN   A 1 542 ? 189.170 176.694 136.184 1.00 70.77  ? 568 GLN   A CG  1 
ATOM   4387 C CD  . GLN   A 1 542 ? 187.747 176.810 136.697 1.00 72.65  ? 568 GLN   A CD  1 
ATOM   4388 O OE1 . GLN   A 1 542 ? 186.801 176.940 135.920 1.00 71.96  ? 568 GLN   A OE1 1 
ATOM   4389 N NE2 . GLN   A 1 542 ? 187.589 176.761 138.014 1.00 69.58  ? 568 GLN   A NE2 1 
ATOM   4390 N N   . LYS   A 1 543 ? 188.298 174.878 131.640 1.00 66.25  ? 569 LYS   A N   1 
ATOM   4391 C CA  . LYS   A 1 543 ? 188.144 175.010 130.192 1.00 65.16  ? 569 LYS   A CA  1 
ATOM   4392 C C   . LYS   A 1 543 ? 186.781 174.475 129.792 1.00 61.81  ? 569 LYS   A C   1 
ATOM   4393 O O   . LYS   A 1 543 ? 186.470 173.315 130.076 1.00 66.46  ? 569 LYS   A O   1 
ATOM   4394 C CB  . LYS   A 1 543 ? 189.251 174.256 129.449 1.00 73.34  ? 569 LYS   A CB  1 
ATOM   4395 C CG  . LYS   A 1 543 ? 189.257 174.487 127.944 1.00 77.74  ? 569 LYS   A CG  1 
ATOM   4396 C CD  . LYS   A 1 543 ? 190.430 173.794 127.263 1.00 82.42  ? 569 LYS   A CD  1 
ATOM   4397 C CE  . LYS   A 1 543 ? 190.249 172.284 127.216 1.00 82.69  ? 569 LYS   A CE  1 
ATOM   4398 N NZ  . LYS   A 1 543 ? 191.325 171.620 126.430 1.00 83.28  ? 569 LYS   A NZ  1 
ATOM   4399 N N   . ASN   A 1 544 ? 185.975 175.312 129.136 1.00 53.21  ? 570 ASN   A N   1 
ATOM   4400 C CA  . ASN   A 1 544 ? 184.655 174.919 128.659 1.00 55.20  ? 570 ASN   A CA  1 
ATOM   4401 C C   . ASN   A 1 544 ? 184.587 175.014 127.143 1.00 59.92  ? 570 ASN   A C   1 
ATOM   4402 O O   . ASN   A 1 544 ? 185.003 176.014 126.552 1.00 65.13  ? 570 ASN   A O   1 
ATOM   4403 C CB  . ASN   A 1 544 ? 183.537 175.762 129.291 1.00 55.61  ? 570 ASN   A CB  1 
ATOM   4404 C CG  . ASN   A 1 544 ? 183.861 177.233 129.344 1.00 63.69  ? 570 ASN   A CG  1 
ATOM   4405 O OD1 . ASN   A 1 544 ? 184.744 177.714 128.635 1.00 64.61  ? 570 ASN   A OD1 1 
ATOM   4406 N ND2 . ASN   A 1 544 ? 183.146 177.963 130.196 1.00 67.33  ? 570 ASN   A ND2 1 
ATOM   4407 N N   . GLN   A 1 545 ? 184.061 173.955 126.527 1.00 61.21  ? 571 GLN   A N   1 
ATOM   4408 C CA  . GLN   A 1 545 ? 183.860 173.873 125.085 1.00 53.21  ? 571 GLN   A CA  1 
ATOM   4409 C C   . GLN   A 1 545 ? 182.372 173.748 124.797 1.00 54.16  ? 571 GLN   A C   1 
ATOM   4410 O O   . GLN   A 1 545 ? 181.676 172.958 125.443 1.00 57.40  ? 571 GLN   A O   1 
ATOM   4411 C CB  . GLN   A 1 545 ? 184.609 172.682 124.488 1.00 55.17  ? 571 GLN   A CB  1 
ATOM   4412 C CG  . GLN   A 1 545 ? 186.118 172.773 124.614 1.00 67.96  ? 571 GLN   A CG  1 
ATOM   4413 C CD  . GLN   A 1 545 ? 186.822 171.558 124.042 1.00 76.60  ? 571 GLN   A CD  1 
ATOM   4414 O OE1 . GLN   A 1 545 ? 186.181 170.615 123.578 1.00 77.32  ? 571 GLN   A OE1 1 
ATOM   4415 N NE2 . GLN   A 1 545 ? 188.150 171.575 124.072 1.00 74.66  ? 571 GLN   A NE2 1 
ATOM   4416 N N   . THR   A 1 546 ? 181.892 174.525 123.828 1.00 54.90  ? 572 THR   A N   1 
ATOM   4417 C CA  . THR   A 1 546 ? 180.478 174.549 123.471 1.00 54.41  ? 572 THR   A CA  1 
ATOM   4418 C C   . THR   A 1 546 ? 180.231 173.559 122.340 1.00 57.03  ? 572 THR   A C   1 
ATOM   4419 O O   . THR   A 1 546 ? 180.757 173.729 121.235 1.00 59.58  ? 572 THR   A O   1 
ATOM   4420 C CB  . THR   A 1 546 ? 180.047 175.953 123.054 1.00 52.04  ? 572 THR   A CB  1 
ATOM   4421 O OG1 . THR   A 1 546 ? 180.617 176.270 121.779 1.00 59.05  ? 572 THR   A OG1 1 
ATOM   4422 C CG2 . THR   A 1 546 ? 180.509 176.975 124.074 1.00 50.58  ? 572 THR   A CG2 1 
ATOM   4423 N N   . LEU   A 1 547 ? 179.426 172.536 122.614 1.00 53.56  ? 573 LEU   A N   1 
ATOM   4424 C CA  . LEU   A 1 547 ? 179.193 171.455 121.670 1.00 52.77  ? 573 LEU   A CA  1 
ATOM   4425 C C   . LEU   A 1 547 ? 177.954 171.755 120.838 1.00 58.64  ? 573 LEU   A C   1 
ATOM   4426 O O   . LEU   A 1 547 ? 176.920 172.161 121.377 1.00 59.23  ? 573 LEU   A O   1 
ATOM   4427 C CB  . LEU   A 1 547 ? 179.024 170.127 122.410 1.00 48.90  ? 573 LEU   A CB  1 
ATOM   4428 C CG  . LEU   A 1 547 ? 180.280 169.372 122.859 1.00 47.19  ? 573 LEU   A CG  1 
ATOM   4429 C CD1 . LEU   A 1 547 ? 181.248 170.260 123.612 1.00 50.65  ? 573 LEU   A CD1 1 
ATOM   4430 C CD2 . LEU   A 1 547 ? 179.882 168.195 123.717 1.00 44.38  ? 573 LEU   A CD2 1 
ATOM   4431 N N   . ARG   A 1 548 ? 178.064 171.551 119.528 1.00 64.81  ? 574 ARG   A N   1 
ATOM   4432 C CA  . ARG   A 1 548 ? 176.934 171.650 118.620 1.00 67.58  ? 574 ARG   A CA  1 
ATOM   4433 C C   . ARG   A 1 548 ? 176.341 170.259 118.411 1.00 67.48  ? 574 ARG   A C   1 
ATOM   4434 O O   . ARG   A 1 548 ? 176.838 169.261 118.938 1.00 69.75  ? 574 ARG   A O   1 
ATOM   4435 C CB  . ARG   A 1 548 ? 177.369 172.282 117.297 1.00 71.49  ? 574 ARG   A CB  1 
ATOM   4436 C CG  . ARG   A 1 548 ? 176.820 173.681 117.061 1.00 75.56  ? 574 ARG   A CG  1 
ATOM   4437 C CD  . ARG   A 1 548 ? 177.353 174.672 118.080 1.00 77.35  ? 574 ARG   A CD  1 
ATOM   4438 N NE  . ARG   A 1 548 ? 177.048 176.050 117.712 1.00 85.72  ? 574 ARG   A NE  1 
ATOM   4439 C CZ  . ARG   A 1 548 ? 177.733 176.777 116.838 1.00 88.92  ? 574 ARG   A CZ  1 
ATOM   4440 N NH1 . ARG   A 1 548 ? 178.782 176.287 116.192 1.00 83.32  ? 574 ARG   A NH1 1 
ATOM   4441 N NH2 . ARG   A 1 548 ? 177.355 178.030 116.601 1.00 89.59  ? 574 ARG   A NH2 1 
ATOM   4442 N N   . GLU   A 1 549 ? 175.265 170.182 117.632 1.00 63.75  ? 575 GLU   A N   1 
ATOM   4443 C CA  . GLU   A 1 549 ? 174.610 168.903 117.403 1.00 58.80  ? 575 GLU   A CA  1 
ATOM   4444 C C   . GLU   A 1 549 ? 175.520 167.975 116.611 1.00 54.56  ? 575 GLU   A C   1 
ATOM   4445 O O   . GLU   A 1 549 ? 176.141 168.378 115.624 1.00 54.67  ? 575 GLU   A O   1 
ATOM   4446 C CB  . GLU   A 1 549 ? 173.288 169.107 116.668 1.00 60.13  ? 575 GLU   A CB  1 
ATOM   4447 C CG  . GLU   A 1 549 ? 172.267 169.903 117.464 1.00 62.81  ? 575 GLU   A CG  1 
ATOM   4448 C CD  . GLU   A 1 549 ? 170.935 170.019 116.757 1.00 68.09  ? 575 GLU   A CD  1 
ATOM   4449 O OE1 . GLU   A 1 549 ? 170.815 169.511 115.623 1.00 69.64  ? 575 GLU   A OE1 1 
ATOM   4450 O OE2 . GLU   A 1 549 ? 170.006 170.620 117.334 1.00 66.36  ? 575 GLU   A OE2 1 
ATOM   4451 N N   . GLY   A 1 550 ? 175.596 166.725 117.053 1.00 50.07  ? 576 GLY   A N   1 
ATOM   4452 C CA  . GLY   A 1 550 ? 176.459 165.745 116.422 1.00 49.87  ? 576 GLY   A CA  1 
ATOM   4453 C C   . GLY   A 1 550 ? 177.942 166.011 116.571 1.00 54.90  ? 576 GLY   A C   1 
ATOM   4454 O O   . GLY   A 1 550 ? 178.688 165.873 115.594 1.00 58.75  ? 576 GLY   A O   1 
ATOM   4455 N N   . GLU   A 1 551 ? 178.388 166.395 117.769 1.00 53.70  ? 577 GLU   A N   1 
ATOM   4456 C CA  . GLU   A 1 551 ? 179.804 166.527 118.090 1.00 52.90  ? 577 GLU   A CA  1 
ATOM   4457 C C   . GLU   A 1 551 ? 180.131 165.692 119.318 1.00 52.69  ? 577 GLU   A C   1 
ATOM   4458 O O   . GLU   A 1 551 ? 179.335 165.615 120.257 1.00 54.81  ? 577 GLU   A O   1 
ATOM   4459 C CB  . GLU   A 1 551 ? 180.196 167.984 118.333 1.00 54.89  ? 577 GLU   A CB  1 
ATOM   4460 C CG  . GLU   A 1 551 ? 180.414 168.779 117.060 1.00 63.51  ? 577 GLU   A CG  1 
ATOM   4461 C CD  . GLU   A 1 551 ? 181.015 170.145 117.318 1.00 72.44  ? 577 GLU   A CD  1 
ATOM   4462 O OE1 . GLU   A 1 551 ? 181.277 170.471 118.494 1.00 75.14  ? 577 GLU   A OE1 1 
ATOM   4463 O OE2 . GLU   A 1 551 ? 181.227 170.895 116.343 1.00 77.58  ? 577 GLU   A OE2 1 
ATOM   4464 N N   . LYS   A 1 552 ? 181.314 165.081 119.306 1.00 51.45  ? 578 LYS   A N   1 
ATOM   4465 C CA  . LYS   A 1 552 ? 181.748 164.140 120.327 1.00 52.73  ? 578 LYS   A CA  1 
ATOM   4466 C C   . LYS   A 1 552 ? 182.997 164.664 121.021 1.00 57.34  ? 578 LYS   A C   1 
ATOM   4467 O O   . LYS   A 1 552 ? 183.855 165.287 120.388 1.00 61.67  ? 578 LYS   A O   1 
ATOM   4468 C CB  . LYS   A 1 552 ? 182.036 162.764 119.718 1.00 55.36  ? 578 LYS   A CB  1 
ATOM   4469 C CG  . LYS   A 1 552 ? 182.426 161.706 120.737 1.00 56.57  ? 578 LYS   A CG  1 
ATOM   4470 C CD  . LYS   A 1 552 ? 182.398 160.299 120.154 1.00 60.10  ? 578 LYS   A CD  1 
ATOM   4471 C CE  . LYS   A 1 552 ? 183.481 160.096 119.109 1.00 65.79  ? 578 LYS   A CE  1 
ATOM   4472 N NZ  . LYS   A 1 552 ? 183.528 158.690 118.621 1.00 72.65  ? 578 LYS   A NZ  1 
ATOM   4473 N N   . MET   A 1 553 ? 183.087 164.410 122.325 1.00 55.19  ? 579 MET   A N   1 
ATOM   4474 C CA  . MET   A 1 553 ? 184.248 164.768 123.127 1.00 56.13  ? 579 MET   A CA  1 
ATOM   4475 C C   . MET   A 1 553 ? 184.654 163.578 123.983 1.00 56.71  ? 579 MET   A C   1 
ATOM   4476 O O   . MET   A 1 553 ? 183.815 162.769 124.390 1.00 58.77  ? 579 MET   A O   1 
ATOM   4477 C CB  . MET   A 1 553 ? 183.959 165.985 124.020 1.00 58.21  ? 579 MET   A CB  1 
ATOM   4478 C CG  . MET   A 1 553 ? 185.152 166.472 124.831 1.00 61.18  ? 579 MET   A CG  1 
ATOM   4479 S SD  . MET   A 1 553 ? 184.814 168.006 125.712 1.00 77.40  ? 579 MET   A SD  1 
ATOM   4480 C CE  . MET   A 1 553 ? 186.333 168.213 126.632 1.00 65.20  ? 579 MET   A CE  1 
ATOM   4481 N N   . GLN   A 1 554 ? 185.955 163.481 124.248 1.00 55.44  ? 580 GLN   A N   1 
ATOM   4482 C CA  . GLN   A 1 554 ? 186.534 162.413 125.055 1.00 54.66  ? 580 GLN   A CA  1 
ATOM   4483 C C   . GLN   A 1 554 ? 186.792 162.961 126.456 1.00 60.74  ? 580 GLN   A C   1 
ATOM   4484 O O   . GLN   A 1 554 ? 187.734 163.731 126.664 1.00 61.74  ? 580 GLN   A O   1 
ATOM   4485 C CB  . GLN   A 1 554 ? 187.821 161.900 124.416 1.00 54.94  ? 580 GLN   A CB  1 
ATOM   4486 C CG  . GLN   A 1 554 ? 188.364 160.626 125.021 1.00 57.31  ? 580 GLN   A CG  1 
ATOM   4487 C CD  . GLN   A 1 554 ? 187.540 159.416 124.657 1.00 58.81  ? 580 GLN   A CD  1 
ATOM   4488 O OE1 . GLN   A 1 554 ? 186.524 159.526 123.974 1.00 59.20  ? 580 GLN   A OE1 1 
ATOM   4489 N NE2 . GLN   A 1 554 ? 187.977 158.248 125.105 1.00 58.97  ? 580 GLN   A NE2 1 
ATOM   4490 N N   . LEU   A 1 555 ? 185.954 162.563 127.412 1.00 56.04  ? 581 LEU   A N   1 
ATOM   4491 C CA  . LEU   A 1 555 ? 186.024 163.120 128.752 1.00 49.69  ? 581 LEU   A CA  1 
ATOM   4492 C C   . LEU   A 1 555 ? 187.213 162.545 129.528 1.00 50.95  ? 581 LEU   A C   1 
ATOM   4493 O O   . LEU   A 1 555 ? 187.634 161.415 129.273 1.00 52.92  ? 581 LEU   A O   1 
ATOM   4494 C CB  . LEU   A 1 555 ? 184.736 162.828 129.508 1.00 47.37  ? 581 LEU   A CB  1 
ATOM   4495 C CG  . LEU   A 1 555 ? 183.479 163.510 128.974 1.00 49.53  ? 581 LEU   A CG  1 
ATOM   4496 C CD1 . LEU   A 1 555 ? 182.247 162.873 129.576 1.00 52.02  ? 581 LEU   A CD1 1 
ATOM   4497 C CD2 . LEU   A 1 555 ? 183.500 165.002 129.258 1.00 52.84  ? 581 LEU   A CD2 1 
ATOM   4498 N N   . PRO   A 1 556 ? 187.780 163.294 130.478 1.00 51.97  ? 582 PRO   A N   1 
ATOM   4499 C CA  . PRO   A 1 556 ? 188.829 162.716 131.326 1.00 49.89  ? 582 PRO   A CA  1 
ATOM   4500 C C   . PRO   A 1 556 ? 188.276 161.665 132.274 1.00 49.59  ? 582 PRO   A C   1 
ATOM   4501 O O   . PRO   A 1 556 ? 187.088 161.640 132.600 1.00 54.09  ? 582 PRO   A O   1 
ATOM   4502 C CB  . PRO   A 1 556 ? 189.372 163.917 132.107 1.00 51.71  ? 582 PRO   A CB  1 
ATOM   4503 C CG  . PRO   A 1 556 ? 188.933 165.100 131.369 1.00 58.24  ? 582 PRO   A CG  1 
ATOM   4504 C CD  . PRO   A 1 556 ? 187.635 164.738 130.737 1.00 58.27  ? 582 PRO   A CD  1 
ATOM   4505 N N   . ALA   A 1 557 ? 189.172 160.786 132.716 1.00 48.24  ? 583 ALA   A N   1 
ATOM   4506 C CA  . ALA   A 1 557 ? 188.879 159.800 133.748 1.00 49.86  ? 583 ALA   A CA  1 
ATOM   4507 C C   . ALA   A 1 557 ? 189.538 160.231 135.051 1.00 52.11  ? 583 ALA   A C   1 
ATOM   4508 O O   . ALA   A 1 557 ? 190.750 160.469 135.087 1.00 56.08  ? 583 ALA   A O   1 
ATOM   4509 C CB  . ALA   A 1 557 ? 189.378 158.416 133.336 1.00 49.98  ? 583 ALA   A CB  1 
ATOM   4510 N N   . GLY   A 1 558 ? 188.742 160.336 136.111 1.00 49.90  ? 584 GLY   A N   1 
ATOM   4511 C CA  . GLY   A 1 558 ? 189.236 160.729 137.415 1.00 51.96  ? 584 GLY   A CA  1 
ATOM   4512 C C   . GLY   A 1 558 ? 189.085 162.193 137.769 1.00 54.47  ? 584 GLY   A C   1 
ATOM   4513 O O   . GLY   A 1 558 ? 189.678 162.628 138.762 1.00 55.93  ? 584 GLY   A O   1 
ATOM   4514 N N   . GLU   A 1 559 ? 188.322 162.963 136.995 1.00 52.32  ? 585 GLU   A N   1 
ATOM   4515 C CA  . GLU   A 1 559 ? 188.111 164.385 137.231 1.00 49.71  ? 585 GLU   A CA  1 
ATOM   4516 C C   . GLU   A 1 559 ? 186.616 164.671 137.278 1.00 45.85  ? 585 GLU   A C   1 
ATOM   4517 O O   . GLU   A 1 559 ? 185.785 163.817 136.961 1.00 46.63  ? 585 GLU   A O   1 
ATOM   4518 C CB  . GLU   A 1 559 ? 188.767 165.240 136.136 1.00 58.73  ? 585 GLU   A CB  1 
ATOM   4519 C CG  . GLU   A 1 559 ? 190.258 165.005 135.951 1.00 62.16  ? 585 GLU   A CG  1 
ATOM   4520 C CD  . GLU   A 1 559 ? 190.839 165.844 134.829 1.00 65.77  ? 585 GLU   A CD  1 
ATOM   4521 O OE1 . GLU   A 1 559 ? 190.076 166.598 134.194 1.00 66.08  ? 585 GLU   A OE1 1 
ATOM   4522 O OE2 . GLU   A 1 559 ? 192.058 165.750 134.583 1.00 63.19  ? 585 GLU   A OE2 1 
ATOM   4523 N N   . TYR   A 1 560 ? 186.281 165.891 137.684 1.00 46.08  ? 586 TYR   A N   1 
ATOM   4524 C CA  . TYR   A 1 560 ? 184.915 166.390 137.647 1.00 47.32  ? 586 TYR   A CA  1 
ATOM   4525 C C   . TYR   A 1 560 ? 184.692 167.117 136.331 1.00 48.23  ? 586 TYR   A C   1 
ATOM   4526 O O   . TYR   A 1 560 ? 185.576 167.835 135.854 1.00 54.60  ? 586 TYR   A O   1 
ATOM   4527 C CB  . TYR   A 1 560 ? 184.632 167.354 138.801 1.00 50.10  ? 586 TYR   A CB  1 
ATOM   4528 C CG  . TYR   A 1 560 ? 184.739 166.778 140.191 1.00 48.07  ? 586 TYR   A CG  1 
ATOM   4529 C CD1 . TYR   A 1 560 ? 185.973 166.598 140.797 1.00 50.90  ? 586 TYR   A CD1 1 
ATOM   4530 C CD2 . TYR   A 1 560 ? 183.605 166.448 140.912 1.00 44.20  ? 586 TYR   A CD2 1 
ATOM   4531 C CE1 . TYR   A 1 560 ? 186.072 166.085 142.070 1.00 51.81  ? 586 TYR   A CE1 1 
ATOM   4532 C CE2 . TYR   A 1 560 ? 183.695 165.937 142.183 1.00 48.63  ? 586 TYR   A CE2 1 
ATOM   4533 C CZ  . TYR   A 1 560 ? 184.930 165.757 142.758 1.00 56.31  ? 586 TYR   A CZ  1 
ATOM   4534 O OH  . TYR   A 1 560 ? 185.021 165.244 144.031 1.00 69.59  ? 586 TYR   A OH  1 
ATOM   4535 N N   . HIS   A 1 561 ? 183.514 166.926 135.744 1.00 42.25  ? 587 HIS   A N   1 
ATOM   4536 C CA  . HIS   A 1 561 ? 183.116 167.690 134.572 1.00 40.11  ? 587 HIS   A CA  1 
ATOM   4537 C C   . HIS   A 1 561 ? 181.662 168.100 134.720 1.00 44.90  ? 587 HIS   A C   1 
ATOM   4538 O O   . HIS   A 1 561 ? 180.839 167.338 135.235 1.00 52.03  ? 587 HIS   A O   1 
ATOM   4539 C CB  . HIS   A 1 561 ? 183.329 166.898 133.277 1.00 37.85  ? 587 HIS   A CB  1 
ATOM   4540 C CG  . HIS   A 1 561 ? 182.353 165.786 133.074 1.00 38.62  ? 587 HIS   A CG  1 
ATOM   4541 N ND1 . HIS   A 1 561 ? 182.559 164.516 133.564 1.00 42.80  ? 587 HIS   A ND1 1 
ATOM   4542 C CD2 . HIS   A 1 561 ? 181.171 165.748 132.417 1.00 43.07  ? 587 HIS   A CD2 1 
ATOM   4543 C CE1 . HIS   A 1 561 ? 181.542 163.745 133.226 1.00 45.68  ? 587 HIS   A CE1 1 
ATOM   4544 N NE2 . HIS   A 1 561 ? 180.685 164.469 132.530 1.00 45.18  ? 587 HIS   A NE2 1 
ATOM   4545 N N   . LYS   A 1 562 ? 181.362 169.314 134.274 1.00 42.60  ? 588 LYS   A N   1 
ATOM   4546 C CA  . LYS   A 1 562 ? 180.017 169.866 134.314 1.00 40.76  ? 588 LYS   A CA  1 
ATOM   4547 C C   . LYS   A 1 562 ? 179.478 169.985 132.898 1.00 41.39  ? 588 LYS   A C   1 
ATOM   4548 O O   . LYS   A 1 562 ? 180.228 170.278 131.966 1.00 48.94  ? 588 LYS   A O   1 
ATOM   4549 C CB  . LYS   A 1 562 ? 180.004 171.237 134.989 1.00 46.79  ? 588 LYS   A CB  1 
ATOM   4550 C CG  . LYS   A 1 562 ? 180.355 171.210 136.460 1.00 49.33  ? 588 LYS   A CG  1 
ATOM   4551 C CD  . LYS   A 1 562 ? 180.319 172.610 137.044 1.00 51.83  ? 588 LYS   A CD  1 
ATOM   4552 C CE  . LYS   A 1 562 ? 180.639 172.617 138.523 1.00 52.92  ? 588 LYS   A CE  1 
ATOM   4553 N NZ  . LYS   A 1 562 ? 180.608 173.992 139.087 1.00 55.76  ? 588 LYS   A NZ  1 
ATOM   4554 N N   . VAL   A 1 563 ? 178.186 169.730 132.737 1.00 40.16  ? 589 VAL   A N   1 
ATOM   4555 C CA  . VAL   A 1 563 ? 177.483 169.945 131.476 1.00 44.46  ? 589 VAL   A CA  1 
ATOM   4556 C C   . VAL   A 1 563 ? 176.369 170.953 131.731 1.00 49.48  ? 589 VAL   A C   1 
ATOM   4557 O O   . VAL   A 1 563 ? 175.500 170.727 132.584 1.00 54.94  ? 589 VAL   A O   1 
ATOM   4558 C CB  . VAL   A 1 563 ? 176.945 168.633 130.878 1.00 44.94  ? 589 VAL   A CB  1 
ATOM   4559 C CG1 . VAL   A 1 563 ? 178.096 167.716 130.518 1.00 45.63  ? 589 VAL   A CG1 1 
ATOM   4560 C CG2 . VAL   A 1 563 ? 175.989 167.920 131.816 1.00 48.66  ? 589 VAL   A CG2 1 
ATOM   4561 N N   . TYR   A 1 564 ? 176.428 172.082 131.024 1.00 42.75  ? 590 TYR   A N   1 
ATOM   4562 C CA  . TYR   A 1 564 ? 175.460 173.162 131.132 1.00 38.17  ? 590 TYR   A CA  1 
ATOM   4563 C C   . TYR   A 1 564 ? 174.587 173.187 129.891 1.00 45.24  ? 590 TYR   A C   1 
ATOM   4564 O O   . TYR   A 1 564 ? 175.080 172.978 128.778 1.00 55.57  ? 590 TYR   A O   1 
ATOM   4565 C CB  . TYR   A 1 564 ? 176.146 174.523 131.259 1.00 43.06  ? 590 TYR   A CB  1 
ATOM   4566 C CG  . TYR   A 1 564 ? 177.106 174.672 132.409 1.00 47.82  ? 590 TYR   A CG  1 
ATOM   4567 C CD1 . TYR   A 1 564 ? 178.403 174.201 132.321 1.00 51.29  ? 590 TYR   A CD1 1 
ATOM   4568 C CD2 . TYR   A 1 564 ? 176.725 175.319 133.571 1.00 49.98  ? 590 TYR   A CD2 1 
ATOM   4569 C CE1 . TYR   A 1 564 ? 179.284 174.348 133.365 1.00 55.23  ? 590 TYR   A CE1 1 
ATOM   4570 C CE2 . TYR   A 1 564 ? 177.598 175.471 134.618 1.00 49.83  ? 590 TYR   A CE2 1 
ATOM   4571 C CZ  . TYR   A 1 564 ? 178.876 174.985 134.511 1.00 53.25  ? 590 TYR   A CZ  1 
ATOM   4572 O OH  . TYR   A 1 564 ? 179.752 175.138 135.559 1.00 57.36  ? 590 TYR   A OH  1 
ATOM   4573 N N   . THR   A 1 565 ? 173.300 173.461 130.083 1.00 46.22  ? 591 THR   A N   1 
ATOM   4574 C CA  . THR   A 1 565 ? 172.362 173.660 128.986 1.00 44.14  ? 591 THR   A CA  1 
ATOM   4575 C C   . THR   A 1 565 ? 172.171 175.154 128.765 1.00 45.55  ? 591 THR   A C   1 
ATOM   4576 O O   . THR   A 1 565 ? 171.858 175.889 129.707 1.00 52.59  ? 591 THR   A O   1 
ATOM   4577 C CB  . THR   A 1 565 ? 171.018 172.994 129.278 1.00 43.78  ? 591 THR   A CB  1 
ATOM   4578 O OG1 . THR   A 1 565 ? 171.215 171.594 129.502 1.00 45.29  ? 591 THR   A OG1 1 
ATOM   4579 C CG2 . THR   A 1 565 ? 170.066 173.181 128.115 1.00 48.62  ? 591 THR   A CG2 1 
ATOM   4580 N N   . THR   A 1 566 ? 172.363 175.596 127.525 1.00 43.66  ? 592 THR   A N   1 
ATOM   4581 C CA  . THR   A 1 566 ? 172.324 177.004 127.154 1.00 45.34  ? 592 THR   A CA  1 
ATOM   4582 C C   . THR   A 1 566 ? 171.441 177.220 125.936 1.00 50.43  ? 592 THR   A C   1 
ATOM   4583 O O   . THR   A 1 566 ? 171.787 177.983 125.030 1.00 56.12  ? 592 THR   A O   1 
ATOM   4584 C CB  . THR   A 1 566 ? 173.728 177.538 126.883 1.00 50.29  ? 592 THR   A CB  1 
ATOM   4585 O OG1 . THR   A 1 566 ? 174.271 176.894 125.725 1.00 52.55  ? 592 THR   A OG1 1 
ATOM   4586 C CG2 . THR   A 1 566 ? 174.638 177.283 128.073 1.00 52.87  ? 592 THR   A CG2 1 
ATOM   4587 N N   . SER   A 1 567 ? 170.295 176.546 125.892 1.00 53.00  ? 593 SER   A N   1 
ATOM   4588 C CA  . SER   A 1 567 ? 169.306 176.707 124.838 1.00 57.92  ? 593 SER   A CA  1 
ATOM   4589 C C   . SER   A 1 567 ? 167.935 176.907 125.464 1.00 57.89  ? 593 SER   A C   1 
ATOM   4590 O O   . SER   A 1 567 ? 167.700 176.446 126.583 1.00 60.72  ? 593 SER   A O   1 
ATOM   4591 C CB  . SER   A 1 567 ? 169.269 175.486 123.908 1.00 60.07  ? 593 SER   A CB  1 
ATOM   4592 O OG  . SER   A 1 567 ? 168.963 174.304 124.627 1.00 62.26  ? 593 SER   A OG  1 
ATOM   4593 N N   . PRO   A 1 568 ? 167.006 177.589 124.779 1.00 57.87  ? 594 PRO   A N   1 
ATOM   4594 C CA  . PRO   A 1 568 ? 165.682 177.804 125.390 1.00 57.12  ? 594 PRO   A CA  1 
ATOM   4595 C C   . PRO   A 1 568 ? 164.892 176.526 125.611 1.00 59.34  ? 594 PRO   A C   1 
ATOM   4596 O O   . PRO   A 1 568 ? 163.967 176.533 126.432 1.00 57.02  ? 594 PRO   A O   1 
ATOM   4597 C CB  . PRO   A 1 568 ? 164.966 178.720 124.387 1.00 57.38  ? 594 PRO   A CB  1 
ATOM   4598 C CG  . PRO   A 1 568 ? 166.018 179.239 123.489 1.00 58.84  ? 594 PRO   A CG  1 
ATOM   4599 C CD  . PRO   A 1 568 ? 167.074 178.195 123.438 1.00 57.02  ? 594 PRO   A CD  1 
ATOM   4600 N N   . SER   A 1 569 ? 165.226 175.441 124.918 1.00 62.29  ? 595 SER   A N   1 
ATOM   4601 C CA  . SER   A 1 569 ? 164.494 174.185 124.942 1.00 59.05  ? 595 SER   A CA  1 
ATOM   4602 C C   . SER   A 1 569 ? 165.373 173.080 125.515 1.00 55.06  ? 595 SER   A C   1 
ATOM   4603 O O   . SER   A 1 569 ? 166.599 173.232 125.587 1.00 56.53  ? 595 SER   A O   1 
ATOM   4604 C CB  . SER   A 1 569 ? 164.030 173.795 123.531 1.00 60.16  ? 595 SER   A CB  1 
ATOM   4605 O OG  . SER   A 1 569 ? 165.137 173.556 122.680 1.00 63.62  ? 595 SER   A OG  1 
ATOM   4606 N N   . PRO   A 1 570 ? 164.785 171.962 125.954 1.00 50.26  ? 596 PRO   A N   1 
ATOM   4607 C CA  . PRO   A 1 570 ? 165.599 170.898 126.551 1.00 51.53  ? 596 PRO   A CA  1 
ATOM   4608 C C   . PRO   A 1 570 ? 166.623 170.335 125.577 1.00 53.61  ? 596 PRO   A C   1 
ATOM   4609 O O   . PRO   A 1 570 ? 166.392 170.268 124.369 1.00 50.54  ? 596 PRO   A O   1 
ATOM   4610 C CB  . PRO   A 1 570 ? 164.566 169.837 126.943 1.00 49.75  ? 596 PRO   A CB  1 
ATOM   4611 C CG  . PRO   A 1 570 ? 163.302 170.568 127.072 1.00 51.86  ? 596 PRO   A CG  1 
ATOM   4612 C CD  . PRO   A 1 570 ? 163.347 171.656 126.060 1.00 54.39  ? 596 PRO   A CD  1 
ATOM   4613 N N   . SER   A 1 571 ? 167.766 169.929 126.127 1.00 55.98  ? 597 SER   A N   1 
ATOM   4614 C CA  . SER   A 1 571 ? 168.876 169.379 125.359 1.00 50.30  ? 597 SER   A CA  1 
ATOM   4615 C C   . SER   A 1 571 ? 169.067 167.911 125.707 1.00 45.52  ? 597 SER   A C   1 
ATOM   4616 O O   . SER   A 1 571 ? 169.035 167.537 126.882 1.00 52.33  ? 597 SER   A O   1 
ATOM   4617 C CB  . SER   A 1 571 ? 170.167 170.148 125.638 1.00 52.99  ? 597 SER   A CB  1 
ATOM   4618 O OG  . SER   A 1 571 ? 170.514 170.080 127.010 1.00 55.88  ? 597 SER   A OG  1 
ATOM   4619 N N   . CYS   A 1 572 ? 169.282 167.090 124.681 1.00 40.62  ? 598 CYS   A N   1 
ATOM   4620 C CA  . CYS   A 1 572 ? 169.414 165.644 124.821 1.00 45.16  ? 598 CYS   A CA  1 
ATOM   4621 C C   . CYS   A 1 572 ? 170.808 165.210 124.393 1.00 43.81  ? 598 CYS   A C   1 
ATOM   4622 O O   . CYS   A 1 572 ? 171.240 165.529 123.278 1.00 52.71  ? 598 CYS   A O   1 
ATOM   4623 C CB  . CYS   A 1 572 ? 168.362 164.919 123.980 1.00 48.20  ? 598 CYS   A CB  1 
ATOM   4624 S SG  . CYS   A 1 572 ? 166.657 165.328 124.408 1.00 73.37  ? 598 CYS   A SG  1 
ATOM   4625 N N   . TYR   A 1 573 ? 171.497 164.469 125.268 1.00 39.31  ? 599 TYR   A N   1 
ATOM   4626 C CA  . TYR   A 1 573 ? 172.842 163.965 124.998 1.00 38.25  ? 599 TYR   A CA  1 
ATOM   4627 C C   . TYR   A 1 573 ? 172.995 162.574 125.610 1.00 40.57  ? 599 TYR   A C   1 
ATOM   4628 O O   . TYR   A 1 573 ? 172.067 162.039 126.223 1.00 48.63  ? 599 TYR   A O   1 
ATOM   4629 C CB  . TYR   A 1 573 ? 173.905 164.941 125.516 1.00 40.10  ? 599 TYR   A CB  1 
ATOM   4630 C CG  . TYR   A 1 573 ? 173.635 165.496 126.891 1.00 44.89  ? 599 TYR   A CG  1 
ATOM   4631 C CD1 . TYR   A 1 573 ? 174.097 164.851 128.024 1.00 41.95  ? 599 TYR   A CD1 1 
ATOM   4632 C CD2 . TYR   A 1 573 ? 172.933 166.680 127.056 1.00 50.07  ? 599 TYR   A CD2 1 
ATOM   4633 C CE1 . TYR   A 1 573 ? 173.856 165.360 129.280 1.00 40.66  ? 599 TYR   A CE1 1 
ATOM   4634 C CE2 . TYR   A 1 573 ? 172.689 167.195 128.308 1.00 48.91  ? 599 TYR   A CE2 1 
ATOM   4635 C CZ  . TYR   A 1 573 ? 173.156 166.532 129.415 1.00 43.71  ? 599 TYR   A CZ  1 
ATOM   4636 O OH  . TYR   A 1 573 ? 172.914 167.046 130.666 1.00 46.97  ? 599 TYR   A OH  1 
ATOM   4637 N N   . MET   A 1 574 ? 174.174 161.974 125.424 1.00 38.25  ? 600 MET   A N   1 
ATOM   4638 C CA  . MET   A 1 574 ? 174.413 160.590 125.819 1.00 38.42  ? 600 MET   A CA  1 
ATOM   4639 C C   . MET   A 1 574 ? 175.854 160.398 126.271 1.00 42.54  ? 600 MET   A C   1 
ATOM   4640 O O   . MET   A 1 574 ? 176.770 161.026 125.735 1.00 49.63  ? 600 MET   A O   1 
ATOM   4641 C CB  . MET   A 1 574 ? 174.105 159.627 124.668 1.00 40.02  ? 600 MET   A CB  1 
ATOM   4642 C CG  . MET   A 1 574 ? 174.955 159.835 123.423 1.00 44.24  ? 600 MET   A CG  1 
ATOM   4643 S SD  . MET   A 1 574 ? 174.454 158.782 122.050 1.00 52.72  ? 600 MET   A SD  1 
ATOM   4644 C CE  . MET   A 1 574 ? 175.109 157.206 122.570 1.00 47.27  ? 600 MET   A CE  1 
ATOM   4645 N N   . TYR   A 1 575 ? 176.037 159.523 127.258 1.00 40.10  ? 601 TYR   A N   1 
ATOM   4646 C CA  . TYR   A 1 575 ? 177.345 159.073 127.722 1.00 40.71  ? 601 TYR   A CA  1 
ATOM   4647 C C   . TYR   A 1 575 ? 177.566 157.646 127.250 1.00 45.02  ? 601 TYR   A C   1 
ATOM   4648 O O   . TYR   A 1 575 ? 176.704 156.788 127.461 1.00 53.05  ? 601 TYR   A O   1 
ATOM   4649 C CB  . TYR   A 1 575 ? 177.443 159.107 129.248 1.00 45.77  ? 601 TYR   A CB  1 
ATOM   4650 C CG  . TYR   A 1 575 ? 177.592 160.472 129.871 1.00 45.83  ? 601 TYR   A CG  1 
ATOM   4651 C CD1 . TYR   A 1 575 ? 178.822 161.099 129.925 1.00 43.41  ? 601 TYR   A CD1 1 
ATOM   4652 C CD2 . TYR   A 1 575 ? 176.508 161.114 130.440 1.00 42.43  ? 601 TYR   A CD2 1 
ATOM   4653 C CE1 . TYR   A 1 575 ? 178.961 162.332 130.501 1.00 45.67  ? 601 TYR   A CE1 1 
ATOM   4654 C CE2 . TYR   A 1 575 ? 176.641 162.346 131.021 1.00 42.05  ? 601 TYR   A CE2 1 
ATOM   4655 C CZ  . TYR   A 1 575 ? 177.866 162.951 131.049 1.00 46.41  ? 601 TYR   A CZ  1 
ATOM   4656 O OH  . TYR   A 1 575 ? 178.003 164.187 131.631 1.00 51.66  ? 601 TYR   A OH  1 
ATOM   4657 N N   . VAL   A 1 576 ? 178.713 157.394 126.624 1.00 44.95  ? 602 VAL   A N   1 
ATOM   4658 C CA  . VAL   A 1 576 ? 179.120 156.061 126.182 1.00 43.55  ? 602 VAL   A CA  1 
ATOM   4659 C C   . VAL   A 1 576 ? 180.440 155.736 126.864 1.00 47.74  ? 602 VAL   A C   1 
ATOM   4660 O O   . VAL   A 1 576 ? 181.405 156.500 126.742 1.00 57.31  ? 602 VAL   A O   1 
ATOM   4661 C CB  . VAL   A 1 576 ? 179.261 155.985 124.656 1.00 44.63  ? 602 VAL   A CB  1 
ATOM   4662 C CG1 . VAL   A 1 576 ? 179.857 154.663 124.255 1.00 46.61  ? 602 VAL   A CG1 1 
ATOM   4663 C CG2 . VAL   A 1 576 ? 177.911 156.188 123.987 1.00 46.73  ? 602 VAL   A CG2 1 
ATOM   4664 N N   . TYR   A 1 577 ? 180.487 154.612 127.583 1.00 46.03  ? 603 TYR   A N   1 
ATOM   4665 C CA  . TYR   A 1 577 ? 181.667 154.274 128.374 1.00 47.60  ? 603 TYR   A CA  1 
ATOM   4666 C C   . TYR   A 1 577 ? 181.923 152.774 128.363 1.00 51.16  ? 603 TYR   A C   1 
ATOM   4667 O O   . TYR   A 1 577 ? 181.024 151.965 128.120 1.00 60.85  ? 603 TYR   A O   1 
ATOM   4668 C CB  . TYR   A 1 577 ? 181.527 154.765 129.817 1.00 46.68  ? 603 TYR   A CB  1 
ATOM   4669 C CG  . TYR   A 1 577 ? 180.342 154.196 130.553 1.00 46.48  ? 603 TYR   A CG  1 
ATOM   4670 C CD1 . TYR   A 1 577 ? 179.100 154.794 130.468 1.00 46.56  ? 603 TYR   A CD1 1 
ATOM   4671 C CD2 . TYR   A 1 577 ? 180.470 153.067 131.344 1.00 48.14  ? 603 TYR   A CD2 1 
ATOM   4672 C CE1 . TYR   A 1 577 ? 178.016 154.281 131.138 1.00 45.95  ? 603 TYR   A CE1 1 
ATOM   4673 C CE2 . TYR   A 1 577 ? 179.390 152.547 132.020 1.00 49.66  ? 603 TYR   A CE2 1 
ATOM   4674 C CZ  . TYR   A 1 577 ? 178.166 153.161 131.914 1.00 50.92  ? 603 TYR   A CZ  1 
ATOM   4675 O OH  . TYR   A 1 577 ? 177.082 152.648 132.587 1.00 55.85  ? 603 TYR   A OH  1 
ATOM   4676 N N   . VAL   A 1 578 ? 183.181 152.420 128.630 1.00 46.10  ? 604 VAL   A N   1 
ATOM   4677 C CA  . VAL   A 1 578 ? 183.622 151.039 128.779 1.00 50.14  ? 604 VAL   A CA  1 
ATOM   4678 C C   . VAL   A 1 578 ? 184.529 150.958 129.998 1.00 54.53  ? 604 VAL   A C   1 
ATOM   4679 O O   . VAL   A 1 578 ? 185.313 151.876 130.260 1.00 58.54  ? 604 VAL   A O   1 
ATOM   4680 C CB  . VAL   A 1 578 ? 184.347 150.523 127.516 1.00 54.30  ? 604 VAL   A CB  1 
ATOM   4681 C CG1 . VAL   A 1 578 ? 185.532 151.409 127.149 1.00 58.88  ? 604 VAL   A CG1 1 
ATOM   4682 C CG2 . VAL   A 1 578 ? 184.800 149.085 127.713 1.00 57.36  ? 604 VAL   A CG2 1 
ATOM   4683 N N   . ASN   A 1 579 ? 184.424 149.859 130.742 1.00 54.35  ? 605 ASN   A N   1 
ATOM   4684 C CA  . ASN   A 1 579 ? 185.195 149.672 131.965 1.00 52.17  ? 605 ASN   A CA  1 
ATOM   4685 C C   . ASN   A 1 579 ? 186.551 149.076 131.613 1.00 54.99  ? 605 ASN   A C   1 
ATOM   4686 O O   . ASN   A 1 579 ? 186.629 147.954 131.103 1.00 62.45  ? 605 ASN   A O   1 
ATOM   4687 C CB  . ASN   A 1 579 ? 184.447 148.769 132.944 1.00 54.86  ? 605 ASN   A CB  1 
ATOM   4688 C CG  . ASN   A 1 579 ? 185.020 148.827 134.351 1.00 61.99  ? 605 ASN   A CG  1 
ATOM   4689 O OD1 . ASN   A 1 579 ? 186.228 148.963 134.540 1.00 65.62  ? 605 ASN   A OD1 1 
ATOM   4690 N ND2 . ASN   A 1 579 ? 184.149 148.726 135.348 1.00 66.69  ? 605 ASN   A ND2 1 
ATOM   4691 N N   . THR   A 1 580 ? 187.617 149.831 131.879 1.00 51.63  ? 606 THR   A N   1 
ATOM   4692 C CA  . THR   A 1 580 ? 188.958 149.368 131.545 1.00 52.55  ? 606 THR   A CA  1 
ATOM   4693 C C   . THR   A 1 580 ? 189.448 148.295 132.511 1.00 62.46  ? 606 THR   A C   1 
ATOM   4694 O O   . THR   A 1 580 ? 190.077 147.319 132.087 1.00 68.89  ? 606 THR   A O   1 
ATOM   4695 C CB  . THR   A 1 580 ? 189.928 150.547 131.534 1.00 57.66  ? 606 THR   A CB  1 
ATOM   4696 O OG1 . THR   A 1 580 ? 189.510 151.503 130.553 1.00 59.40  ? 606 THR   A OG1 1 
ATOM   4697 C CG2 . THR   A 1 580 ? 191.339 150.079 131.212 1.00 61.32  ? 606 THR   A CG2 1 
ATOM   4698 N N   . THR   A 1 581 ? 189.183 148.461 133.810 1.00 63.01  ? 607 THR   A N   1 
ATOM   4699 C CA  . THR   A 1 581 ? 189.663 147.492 134.793 1.00 59.75  ? 607 THR   A CA  1 
ATOM   4700 C C   . THR   A 1 581 ? 189.015 146.130 134.590 1.00 63.05  ? 607 THR   A C   1 
ATOM   4701 O O   . THR   A 1 581 ? 189.690 145.098 134.675 1.00 70.23  ? 607 THR   A O   1 
ATOM   4702 C CB  . THR   A 1 581 ? 189.400 148.002 136.208 1.00 59.55  ? 607 THR   A CB  1 
ATOM   4703 O OG1 . THR   A 1 581 ? 190.172 149.185 136.442 1.00 63.95  ? 607 THR   A OG1 1 
ATOM   4704 C CG2 . THR   A 1 581 ? 189.773 146.953 137.241 1.00 64.53  ? 607 THR   A CG2 1 
ATOM   4705 N N   . GLU   A 1 582 ? 187.707 146.106 134.330 1.00 62.70  ? 608 GLU   A N   1 
ATOM   4706 C CA  . GLU   A 1 582 ? 187.028 144.840 134.086 1.00 65.12  ? 608 GLU   A CA  1 
ATOM   4707 C C   . GLU   A 1 582 ? 187.582 144.157 132.845 1.00 67.92  ? 608 GLU   A C   1 
ATOM   4708 O O   . GLU   A 1 582 ? 187.798 142.941 132.843 1.00 77.40  ? 608 GLU   A O   1 
ATOM   4709 C CB  . GLU   A 1 582 ? 185.525 145.068 133.941 1.00 68.91  ? 608 GLU   A CB  1 
ATOM   4710 C CG  . GLU   A 1 582 ? 184.704 143.792 133.838 1.00 74.15  ? 608 GLU   A CG  1 
ATOM   4711 C CD  . GLU   A 1 582 ? 183.212 144.060 133.826 1.00 78.81  ? 608 GLU   A CD  1 
ATOM   4712 O OE1 . GLU   A 1 582 ? 182.819 145.243 133.895 1.00 77.25  ? 608 GLU   A OE1 1 
ATOM   4713 O OE2 . GLU   A 1 582 ? 182.432 143.088 133.747 1.00 79.98  ? 608 GLU   A OE2 1 
ATOM   4714 N N   . LEU   A 1 583 ? 187.822 144.925 131.781 1.00 63.80  ? 609 LEU   A N   1 
ATOM   4715 C CA  . LEU   A 1 583 ? 188.366 144.341 130.561 1.00 67.36  ? 609 LEU   A CA  1 
ATOM   4716 C C   . LEU   A 1 583 ? 189.766 143.785 130.792 1.00 69.46  ? 609 LEU   A C   1 
ATOM   4717 O O   . LEU   A 1 583 ? 190.096 142.694 130.311 1.00 77.74  ? 609 LEU   A O   1 
ATOM   4718 C CB  . LEU   A 1 583 ? 188.377 145.388 129.448 1.00 65.42  ? 609 LEU   A CB  1 
ATOM   4719 C CG  . LEU   A 1 583 ? 188.627 144.904 128.020 1.00 68.63  ? 609 LEU   A CG  1 
ATOM   4720 C CD1 . LEU   A 1 583 ? 187.501 144.004 127.535 1.00 73.21  ? 609 LEU   A CD1 1 
ATOM   4721 C CD2 . LEU   A 1 583 ? 188.796 146.090 127.089 1.00 67.66  ? 609 LEU   A CD2 1 
ATOM   4722 N N   . ALA   A 1 584 ? 190.607 144.520 131.522 1.00 64.96  ? 610 ALA   A N   1 
ATOM   4723 C CA  . ALA   A 1 584 ? 191.960 144.043 131.790 1.00 65.03  ? 610 ALA   A CA  1 
ATOM   4724 C C   . ALA   A 1 584 ? 191.942 142.782 132.645 1.00 72.04  ? 610 ALA   A C   1 
ATOM   4725 O O   . ALA   A 1 584 ? 192.691 141.831 132.381 1.00 80.65  ? 610 ALA   A O   1 
ATOM   4726 C CB  . ALA   A 1 584 ? 192.774 145.141 132.472 1.00 60.90  ? 610 ALA   A CB  1 
ATOM   4727 N N   . LEU   A 1 585 ? 191.093 142.756 133.674 1.00 71.51  ? 611 LEU   A N   1 
ATOM   4728 C CA  . LEU   A 1 585 ? 190.972 141.563 134.503 1.00 73.72  ? 611 LEU   A CA  1 
ATOM   4729 C C   . LEU   A 1 585 ? 190.474 140.383 133.684 1.00 80.46  ? 611 LEU   A C   1 
ATOM   4730 O O   . LEU   A 1 585 ? 190.972 139.262 133.834 1.00 90.95  ? 611 LEU   A O   1 
ATOM   4731 C CB  . LEU   A 1 585 ? 190.032 141.841 135.678 1.00 75.10  ? 611 LEU   A CB  1 
ATOM   4732 C CG  . LEU   A 1 585 ? 189.526 140.663 136.516 1.00 82.93  ? 611 LEU   A CG  1 
ATOM   4733 C CD1 . LEU   A 1 585 ? 190.681 139.850 137.077 1.00 90.18  ? 611 LEU   A CD1 1 
ATOM   4734 C CD2 . LEU   A 1 585 ? 188.643 141.173 137.639 1.00 83.97  ? 611 LEU   A CD2 1 
ATOM   4735 N N   . GLU   A 1 586 ? 189.499 140.618 132.803 1.00 76.28  ? 612 GLU   A N   1 
ATOM   4736 C CA  . GLU   A 1 586 ? 188.984 139.541 131.967 1.00 77.49  ? 612 GLU   A CA  1 
ATOM   4737 C C   . GLU   A 1 586 ? 190.063 139.000 131.039 1.00 80.83  ? 612 GLU   A C   1 
ATOM   4738 O O   . GLU   A 1 586 ? 190.195 137.783 130.879 1.00 89.49  ? 612 GLU   A O   1 
ATOM   4739 C CB  . GLU   A 1 586 ? 187.781 140.036 131.166 1.00 79.79  ? 612 GLU   A CB  1 
ATOM   4740 C CG  . GLU   A 1 586 ? 187.046 138.944 130.404 1.00 91.41  ? 612 GLU   A CG  1 
ATOM   4741 C CD  . GLU   A 1 586 ? 185.799 139.455 129.710 1.00 99.71  ? 612 GLU   A CD  1 
ATOM   4742 O OE1 . GLU   A 1 586 ? 185.503 140.663 129.829 1.00 98.52  ? 612 GLU   A OE1 1 
ATOM   4743 O OE2 . GLU   A 1 586 ? 185.114 138.650 129.046 1.00 100.76 ? 612 GLU   A OE2 1 
ATOM   4744 N N   . GLN   A 1 587 ? 190.853 139.884 130.426 1.00 76.97  ? 613 GLN   A N   1 
ATOM   4745 C CA  . GLN   A 1 587 ? 191.908 139.426 129.527 1.00 77.58  ? 613 GLN   A CA  1 
ATOM   4746 C C   . GLN   A 1 587 ? 192.977 138.636 130.274 1.00 86.43  ? 613 GLN   A C   1 
ATOM   4747 O O   . GLN   A 1 587 ? 193.423 137.583 129.799 1.00 98.60  ? 613 GLN   A O   1 
ATOM   4748 C CB  . GLN   A 1 587 ? 192.533 140.613 128.799 1.00 79.33  ? 613 GLN   A CB  1 
ATOM   4749 C CG  . GLN   A 1 587 ? 191.656 141.194 127.706 1.00 81.88  ? 613 GLN   A CG  1 
ATOM   4750 C CD  . GLN   A 1 587 ? 192.334 142.317 126.947 1.00 84.10  ? 613 GLN   A CD  1 
ATOM   4751 O OE1 . GLN   A 1 587 ? 193.505 142.619 127.177 1.00 80.97  ? 613 GLN   A OE1 1 
ATOM   4752 N NE2 . GLN   A 1 587 ? 191.599 142.944 126.036 1.00 82.83  ? 613 GLN   A NE2 1 
ATOM   4753 N N   . ASP   A 1 588 ? 193.410 139.127 131.438 1.00 85.01  ? 614 ASP   A N   1 
ATOM   4754 C CA  . ASP   A 1 588 ? 194.431 138.405 132.193 1.00 92.03  ? 614 ASP   A CA  1 
ATOM   4755 C C   . ASP   A 1 588 ? 193.911 137.055 132.671 1.00 98.98  ? 614 ASP   A C   1 
ATOM   4756 O O   . ASP   A 1 588 ? 194.623 136.044 132.605 1.00 106.57 ? 614 ASP   A O   1 
ATOM   4757 C CB  . ASP   A 1 588 ? 194.901 139.247 133.376 1.00 96.80  ? 614 ASP   A CB  1 
ATOM   4758 C CG  . ASP   A 1 588 ? 195.605 140.516 132.943 1.00 100.93 ? 614 ASP   A CG  1 
ATOM   4759 O OD1 . ASP   A 1 588 ? 195.760 140.721 131.721 1.00 99.45  ? 614 ASP   A OD1 1 
ATOM   4760 O OD2 . ASP   A 1 588 ? 196.004 141.308 133.822 1.00 103.91 ? 614 ASP   A OD2 1 
ATOM   4761 N N   . LEU   A 1 589 ? 192.663 137.015 133.143 1.00 95.68  ? 615 LEU   A N   1 
ATOM   4762 C CA  . LEU   A 1 589 ? 192.069 135.753 133.559 1.00 97.46  ? 615 LEU   A CA  1 
ATOM   4763 C C   . LEU   A 1 589 ? 191.947 134.794 132.383 1.00 99.50  ? 615 LEU   A C   1 
ATOM   4764 O O   . LEU   A 1 589 ? 192.149 133.588 132.536 1.00 108.64 ? 615 LEU   A O   1 
ATOM   4765 C CB  . LEU   A 1 589 ? 190.705 136.018 134.196 1.00 100.39 ? 615 LEU   A CB  1 
ATOM   4766 C CG  . LEU   A 1 589 ? 190.097 134.920 135.075 1.00 112.04 ? 615 LEU   A CG  1 
ATOM   4767 C CD1 . LEU   A 1 589 ? 189.134 135.536 136.082 1.00 113.04 ? 615 LEU   A CD1 1 
ATOM   4768 C CD2 . LEU   A 1 589 ? 189.385 133.845 134.253 1.00 114.35 ? 615 LEU   A CD2 1 
ATOM   4769 N N   . ALA   A 1 590 ? 191.602 135.309 131.202 1.00 95.62  ? 616 ALA   A N   1 
ATOM   4770 C CA  . ALA   A 1 590 ? 191.493 134.452 130.028 1.00 99.52  ? 616 ALA   A CA  1 
ATOM   4771 C C   . ALA   A 1 590 ? 192.846 133.872 129.643 1.00 106.55 ? 616 ALA   A C   1 
ATOM   4772 O O   . ALA   A 1 590 ? 192.940 132.699 129.267 1.00 112.20 ? 616 ALA   A O   1 
ATOM   4773 C CB  . ALA   A 1 590 ? 190.895 135.236 128.861 1.00 98.35  ? 616 ALA   A CB  1 
ATOM   4774 N N   . TYR   A 1 591 ? 193.902 134.683 129.713 1.00 109.94 ? 617 TYR   A N   1 
ATOM   4775 C CA  . TYR   A 1 591 ? 195.243 134.167 129.457 1.00 113.35 ? 617 TYR   A CA  1 
ATOM   4776 C C   . TYR   A 1 591 ? 195.608 133.081 130.461 1.00 112.47 ? 617 TYR   A C   1 
ATOM   4777 O O   . TYR   A 1 591 ? 196.168 132.039 130.091 1.00 117.74 ? 617 TYR   A O   1 
ATOM   4778 C CB  . TYR   A 1 591 ? 196.255 135.313 129.508 1.00 115.30 ? 617 TYR   A CB  1 
ATOM   4779 C CG  . TYR   A 1 591 ? 197.700 134.886 129.362 1.00 119.61 ? 617 TYR   A CG  1 
ATOM   4780 C CD1 . TYR   A 1 591 ? 198.255 134.661 128.111 1.00 119.39 ? 617 TYR   A CD1 1 
ATOM   4781 C CD2 . TYR   A 1 591 ? 198.512 134.726 130.476 1.00 121.05 ? 617 TYR   A CD2 1 
ATOM   4782 C CE1 . TYR   A 1 591 ? 199.574 134.279 127.974 1.00 122.59 ? 617 TYR   A CE1 1 
ATOM   4783 C CE2 . TYR   A 1 591 ? 199.831 134.343 130.349 1.00 122.40 ? 617 TYR   A CE2 1 
ATOM   4784 C CZ  . TYR   A 1 591 ? 200.358 134.122 129.096 1.00 123.48 ? 617 TYR   A CZ  1 
ATOM   4785 O OH  . TYR   A 1 591 ? 201.673 133.740 128.964 1.00 122.24 ? 617 TYR   A OH  1 
ATOM   4786 N N   . LEU   A 1 592 ? 195.287 133.305 131.736 1.00 109.99 ? 618 LEU   A N   1 
ATOM   4787 C CA  . LEU   A 1 592 ? 195.548 132.294 132.755 1.00 115.98 ? 618 LEU   A CA  1 
ATOM   4788 C C   . LEU   A 1 592 ? 194.778 131.009 132.468 1.00 121.59 ? 618 LEU   A C   1 
ATOM   4789 O O   . LEU   A 1 592 ? 195.316 129.906 132.618 1.00 129.41 ? 618 LEU   A O   1 
ATOM   4790 C CB  . LEU   A 1 592 ? 195.182 132.846 134.133 1.00 120.37 ? 618 LEU   A CB  1 
ATOM   4791 C CG  . LEU   A 1 592 ? 195.485 131.972 135.354 1.00 130.87 ? 618 LEU   A CG  1 
ATOM   4792 C CD1 . LEU   A 1 592 ? 196.975 131.678 135.465 1.00 132.27 ? 618 LEU   A CD1 1 
ATOM   4793 C CD2 . LEU   A 1 592 ? 194.975 132.643 136.621 1.00 133.47 ? 618 LEU   A CD2 1 
ATOM   4794 N N   . GLN   A 1 593 ? 193.514 131.134 132.064 1.00 120.19 ? 619 GLN   A N   1 
ATOM   4795 C CA  . GLN   A 1 593 ? 192.704 129.959 131.756 1.00 122.46 ? 619 GLN   A CA  1 
ATOM   4796 C C   . GLN   A 1 593 ? 193.255 129.212 130.550 1.00 121.16 ? 619 GLN   A C   1 
ATOM   4797 O O   . GLN   A 1 593 ? 193.240 127.977 130.518 1.00 124.13 ? 619 GLN   A O   1 
ATOM   4798 C CB  . GLN   A 1 593 ? 191.253 130.375 131.514 1.00 122.19 ? 619 GLN   A CB  1 
ATOM   4799 C CG  . GLN   A 1 593 ? 190.312 129.224 131.172 1.00 124.72 ? 619 GLN   A CG  1 
ATOM   4800 C CD  . GLN   A 1 593 ? 188.857 129.651 131.142 1.00 126.65 ? 619 GLN   A CD  1 
ATOM   4801 O OE1 . GLN   A 1 593 ? 188.528 130.798 131.444 1.00 126.26 ? 619 GLN   A OE1 1 
ATOM   4802 N NE2 . GLN   A 1 593 ? 187.977 128.728 130.773 1.00 125.29 ? 619 GLN   A NE2 1 
ATOM   4803 N N   . GLU   A 1 594 ? 193.725 129.945 129.541 1.00 117.52 ? 620 GLU   A N   1 
ATOM   4804 C CA  . GLU   A 1 594 ? 194.331 129.301 128.382 1.00 123.41 ? 620 GLU   A CA  1 
ATOM   4805 C C   . GLU   A 1 594 ? 195.583 128.534 128.781 1.00 127.17 ? 620 GLU   A C   1 
ATOM   4806 O O   . GLU   A 1 594 ? 195.803 127.407 128.322 1.00 133.19 ? 620 GLU   A O   1 
ATOM   4807 C CB  . GLU   A 1 594 ? 194.653 130.347 127.314 1.00 127.99 ? 620 GLU   A CB  1 
ATOM   4808 C CG  . GLU   A 1 594 ? 195.186 129.770 126.009 1.00 130.40 ? 620 GLU   A CG  1 
ATOM   4809 C CD  . GLU   A 1 594 ? 195.343 130.822 124.928 1.00 129.09 ? 620 GLU   A CD  1 
ATOM   4810 O OE1 . GLU   A 1 594 ? 195.054 132.006 125.202 1.00 125.69 ? 620 GLU   A OE1 1 
ATOM   4811 O OE2 . GLU   A 1 594 ? 195.754 130.465 123.804 1.00 130.35 ? 620 GLU   A OE2 1 
ATOM   4812 N N   . LEU   A 1 595 ? 196.417 129.129 129.637 1.00 127.58 ? 621 LEU   A N   1 
ATOM   4813 C CA  . LEU   A 1 595 ? 197.600 128.420 130.116 1.00 130.58 ? 621 LEU   A CA  1 
ATOM   4814 C C   . LEU   A 1 595 ? 197.214 127.177 130.912 1.00 132.34 ? 621 LEU   A C   1 
ATOM   4815 O O   . LEU   A 1 595 ? 197.848 126.123 130.779 1.00 136.02 ? 621 LEU   A O   1 
ATOM   4816 C CB  . LEU   A 1 595 ? 198.471 129.351 130.962 1.00 133.44 ? 621 LEU   A CB  1 
ATOM   4817 C CG  . LEU   A 1 595 ? 199.606 130.070 130.225 1.00 132.03 ? 621 LEU   A CG  1 
ATOM   4818 C CD1 . LEU   A 1 595 ? 199.091 130.988 129.121 1.00 128.69 ? 621 LEU   A CD1 1 
ATOM   4819 C CD2 . LEU   A 1 595 ? 200.457 130.853 131.213 1.00 128.71 ? 621 LEU   A CD2 1 
ATOM   4820 N N   . LYS   A 1 596 ? 196.180 127.285 131.749 1.00 131.21 ? 622 LYS   A N   1 
ATOM   4821 C CA  . LYS   A 1 596 ? 195.715 126.128 132.509 1.00 130.66 ? 622 LYS   A CA  1 
ATOM   4822 C C   . LYS   A 1 596 ? 195.241 125.016 131.583 1.00 129.88 ? 622 LYS   A C   1 
ATOM   4823 O O   . LYS   A 1 596 ? 195.564 123.843 131.795 1.00 134.42 ? 622 LYS   A O   1 
ATOM   4824 C CB  . LYS   A 1 596 ? 194.592 126.549 133.458 1.00 132.56 ? 622 LYS   A CB  1 
ATOM   4825 C CG  . LYS   A 1 596 ? 194.021 125.418 134.314 1.00 137.15 ? 622 LYS   A CG  1 
ATOM   4826 C CD  . LYS   A 1 596 ? 192.992 125.922 135.324 1.00 137.98 ? 622 LYS   A CD  1 
ATOM   4827 C CE  . LYS   A 1 596 ? 191.567 125.856 134.782 1.00 136.97 ? 622 LYS   A CE  1 
ATOM   4828 N NZ  . LYS   A 1 596 ? 191.342 126.735 133.600 1.00 133.53 ? 622 LYS   A NZ  1 
ATOM   4829 N N   . GLU   A 1 597 ? 194.466 125.365 130.558 1.00 128.03 ? 623 GLU   A N   1 
ATOM   4830 C CA  . GLU   A 1 597 ? 193.993 124.362 129.611 1.00 133.43 ? 623 GLU   A CA  1 
ATOM   4831 C C   . GLU   A 1 597 ? 195.156 123.721 128.866 1.00 136.62 ? 623 GLU   A C   1 
ATOM   4832 O O   . GLU   A 1 597 ? 195.159 122.507 128.630 1.00 138.25 ? 623 GLU   A O   1 
ATOM   4833 C CB  . GLU   A 1 597 ? 193.004 124.992 128.630 1.00 138.76 ? 623 GLU   A CB  1 
ATOM   4834 C CG  . GLU   A 1 597 ? 191.670 125.367 129.256 1.00 138.99 ? 623 GLU   A CG  1 
ATOM   4835 C CD  . GLU   A 1 597 ? 190.743 126.069 128.283 1.00 140.16 ? 623 GLU   A CD  1 
ATOM   4836 O OE1 . GLU   A 1 597 ? 191.126 126.229 127.105 1.00 141.22 ? 623 GLU   A OE1 1 
ATOM   4837 O OE2 . GLU   A 1 597 ? 189.632 126.461 128.697 1.00 139.19 ? 623 GLU   A OE2 1 
ATOM   4838 N N   . LYS   A 1 598 ? 196.149 124.525 128.479 1.00 139.74 ? 624 LYS   A N   1 
ATOM   4839 C CA  . LYS   A 1 598 ? 197.331 123.977 127.820 1.00 144.53 ? 624 LYS   A CA  1 
ATOM   4840 C C   . LYS   A 1 598 ? 198.060 122.997 128.730 1.00 146.20 ? 624 LYS   A C   1 
ATOM   4841 O O   . LYS   A 1 598 ? 198.543 121.954 128.274 1.00 148.09 ? 624 LYS   A O   1 
ATOM   4842 C CB  . LYS   A 1 598 ? 198.264 125.110 127.394 1.00 144.17 ? 624 LYS   A CB  1 
ATOM   4843 C CG  . LYS   A 1 598 ? 197.782 125.885 126.178 1.00 141.49 ? 624 LYS   A CG  1 
ATOM   4844 C CD  . LYS   A 1 598 ? 198.705 127.051 125.861 1.00 139.25 ? 624 LYS   A CD  1 
ATOM   4845 C CE  . LYS   A 1 598 ? 198.274 127.775 124.596 1.00 136.55 ? 624 LYS   A CE  1 
ATOM   4846 N NZ  . LYS   A 1 598 ? 199.096 128.989 124.337 1.00 133.08 ? 624 LYS   A NZ  1 
ATOM   4847 N N   . VAL   A 1 599 ? 198.163 123.322 130.020 1.00 145.78 ? 625 VAL   A N   1 
ATOM   4848 C CA  . VAL   A 1 599 ? 198.768 122.395 130.972 1.00 146.16 ? 625 VAL   A CA  1 
ATOM   4849 C C   . VAL   A 1 599 ? 197.941 121.118 131.069 1.00 141.74 ? 625 VAL   A C   1 
ATOM   4850 O O   . VAL   A 1 599 ? 198.487 120.011 131.141 1.00 141.04 ? 625 VAL   A O   1 
ATOM   4851 C CB  . VAL   A 1 599 ? 198.935 123.072 132.346 1.00 148.16 ? 625 VAL   A CB  1 
ATOM   4852 C CG1 . VAL   A 1 599 ? 199.307 122.049 133.415 1.00 149.27 ? 625 VAL   A CG1 1 
ATOM   4853 C CG2 . VAL   A 1 599 ? 199.995 124.165 132.277 1.00 148.39 ? 625 VAL   A CG2 1 
ATOM   4854 N N   . GLU   A 1 600 ? 196.613 121.252 131.077 1.00 140.29 ? 626 GLU   A N   1 
ATOM   4855 C CA  . GLU   A 1 600 ? 195.749 120.092 131.272 1.00 140.94 ? 626 GLU   A CA  1 
ATOM   4856 C C   . GLU   A 1 600 ? 195.850 119.111 130.109 1.00 141.51 ? 626 GLU   A C   1 
ATOM   4857 O O   . GLU   A 1 600 ? 195.943 117.898 130.323 1.00 142.22 ? 626 GLU   A O   1 
ATOM   4858 C CB  . GLU   A 1 600 ? 194.303 120.544 131.464 1.00 142.64 ? 626 GLU   A CB  1 
ATOM   4859 C CG  . GLU   A 1 600 ? 194.016 121.121 132.841 1.00 145.26 ? 626 GLU   A CG  1 
ATOM   4860 C CD  . GLU   A 1 600 ? 192.600 121.646 132.971 1.00 145.33 ? 626 GLU   A CD  1 
ATOM   4861 O OE1 . GLU   A 1 600 ? 191.826 121.520 131.999 1.00 144.25 ? 626 GLU   A OE1 1 
ATOM   4862 O OE2 . GLU   A 1 600 ? 192.261 122.187 134.045 1.00 144.05 ? 626 GLU   A OE2 1 
ATOM   4863 N N   . ASN   A 1 601 ? 195.836 119.610 128.874 1.00 143.90 ? 627 ASN   A N   1 
ATOM   4864 C CA  . ASN   A 1 601 ? 195.870 118.729 127.711 1.00 145.37 ? 627 ASN   A CA  1 
ATOM   4865 C C   . ASN   A 1 601 ? 197.258 118.163 127.426 1.00 147.12 ? 627 ASN   A C   1 
ATOM   4866 O O   . ASN   A 1 601 ? 197.393 117.359 126.497 1.00 147.93 ? 627 ASN   A O   1 
ATOM   4867 C CB  . ASN   A 1 601 ? 195.336 119.455 126.466 1.00 145.00 ? 627 ASN   A CB  1 
ATOM   4868 C CG  . ASN   A 1 601 ? 196.104 120.731 126.133 1.00 148.14 ? 627 ASN   A CG  1 
ATOM   4869 O OD1 . ASN   A 1 601 ? 197.332 120.778 126.196 1.00 150.80 ? 627 ASN   A OD1 1 
ATOM   4870 N ND2 . ASN   A 1 601 ? 195.368 121.775 125.767 1.00 146.79 ? 627 ASN   A ND2 1 
ATOM   4871 N N   . GLY   A 1 602 ? 198.283 118.559 128.186 1.00 146.69 ? 628 GLY   A N   1 
ATOM   4872 C CA  . GLY   A 1 602 ? 199.629 118.058 128.027 1.00 147.11 ? 628 GLY   A CA  1 
ATOM   4873 C C   . GLY   A 1 602 ? 200.586 119.019 127.353 1.00 151.58 ? 628 GLY   A C   1 
ATOM   4874 O O   . GLY   A 1 602 ? 201.804 118.827 127.451 1.00 154.86 ? 628 GLY   A O   1 
ATOM   4875 N N   . SER   A 1 603 ? 200.075 120.044 126.676 1.00 154.05 ? 629 SER   A N   1 
ATOM   4876 C CA  . SER   A 1 603 ? 200.944 121.033 126.061 1.00 158.43 ? 629 SER   A CA  1 
ATOM   4877 C C   . SER   A 1 603 ? 201.637 121.865 127.140 1.00 164.07 ? 629 SER   A C   1 
ATOM   4878 O O   . SER   A 1 603 ? 201.376 121.724 128.338 1.00 162.13 ? 629 SER   A O   1 
ATOM   4879 C CB  . SER   A 1 603 ? 200.146 121.928 125.114 1.00 152.79 ? 629 SER   A CB  1 
ATOM   4880 O OG  . SER   A 1 603 ? 199.117 122.614 125.803 1.00 151.52 ? 629 SER   A OG  1 
ATOM   4881 N N   . GLU   A 1 604 ? 202.534 122.748 126.696 1.00 170.25 ? 630 GLU   A N   1 
ATOM   4882 C CA  . GLU   A 1 604 ? 203.365 123.551 127.592 1.00 173.37 ? 630 GLU   A CA  1 
ATOM   4883 C C   . GLU   A 1 604 ? 204.193 122.643 128.505 1.00 177.84 ? 630 GLU   A C   1 
ATOM   4884 O O   . GLU   A 1 604 ? 204.053 122.641 129.730 1.00 177.36 ? 630 GLU   A O   1 
ATOM   4885 C CB  . GLU   A 1 604 ? 202.506 124.529 128.406 1.00 168.05 ? 630 GLU   A CB  1 
ATOM   4886 C CG  . GLU   A 1 604 ? 203.294 125.592 129.171 1.00 168.61 ? 630 GLU   A CG  1 
ATOM   4887 C CD  . GLU   A 1 604 ? 203.990 126.588 128.261 1.00 168.14 ? 630 GLU   A CD  1 
ATOM   4888 O OE1 . GLU   A 1 604 ? 203.709 126.586 127.044 1.00 169.31 ? 630 GLU   A OE1 1 
ATOM   4889 O OE2 . GLU   A 1 604 ? 204.820 127.374 128.765 1.00 165.24 ? 630 GLU   A OE2 1 
ATOM   4890 N N   . THR   A 1 605 ? 205.063 121.853 127.869 1.00 180.92 ? 631 THR   A N   1 
ATOM   4891 C CA  . THR   A 1 605 ? 205.875 120.879 128.592 1.00 182.38 ? 631 THR   A CA  1 
ATOM   4892 C C   . THR   A 1 605 ? 206.810 121.524 129.609 1.00 185.14 ? 631 THR   A C   1 
ATOM   4893 O O   . THR   A 1 605 ? 207.252 120.843 130.540 1.00 185.34 ? 631 THR   A O   1 
ATOM   4894 C CB  . THR   A 1 605 ? 206.694 120.045 127.604 1.00 180.88 ? 631 THR   A CB  1 
ATOM   4895 O OG1 . THR   A 1 605 ? 207.507 120.911 126.802 1.00 180.58 ? 631 THR   A OG1 1 
ATOM   4896 C CG2 . THR   A 1 605 ? 205.778 119.229 126.701 1.00 176.61 ? 631 THR   A CG2 1 
ATOM   4897 N N   . GLY   A 1 606 ? 207.124 122.809 129.457 1.00 184.57 ? 632 GLY   A N   1 
ATOM   4898 C CA  . GLY   A 1 606 ? 207.981 123.496 130.393 1.00 182.54 ? 632 GLY   A CA  1 
ATOM   4899 C C   . GLY   A 1 606 ? 207.360 123.557 131.776 1.00 183.93 ? 632 GLY   A C   1 
ATOM   4900 O O   . GLY   A 1 606 ? 206.146 123.391 131.934 1.00 184.54 ? 632 GLY   A O   1 
ATOM   4901 N N   . PRO   A 1 607 ? 208.177 123.781 132.808 1.00 184.62 ? 633 PRO   A N   1 
ATOM   4902 C CA  . PRO   A 1 607 ? 207.644 123.772 134.176 1.00 182.54 ? 633 PRO   A CA  1 
ATOM   4903 C C   . PRO   A 1 607 ? 206.627 124.882 134.396 1.00 181.18 ? 633 PRO   A C   1 
ATOM   4904 O O   . PRO   A 1 607 ? 206.772 125.997 133.889 1.00 181.38 ? 633 PRO   A O   1 
ATOM   4905 C CB  . PRO   A 1 607 ? 208.891 123.969 135.043 1.00 179.44 ? 633 PRO   A CB  1 
ATOM   4906 C CG  . PRO   A 1 607 ? 209.841 124.698 134.169 1.00 181.28 ? 633 PRO   A CG  1 
ATOM   4907 C CD  . PRO   A 1 607 ? 209.592 124.194 132.776 1.00 182.08 ? 633 PRO   A CD  1 
ATOM   4908 N N   . LEU   A 1 608 ? 205.590 124.564 135.165 1.00 177.55 ? 634 LEU   A N   1 
ATOM   4909 C CA  . LEU   A 1 608 ? 204.581 125.555 135.490 1.00 173.77 ? 634 LEU   A CA  1 
ATOM   4910 C C   . LEU   A 1 608 ? 205.168 126.612 136.430 1.00 172.70 ? 634 LEU   A C   1 
ATOM   4911 O O   . LEU   A 1 608 ? 206.070 126.312 137.217 1.00 172.43 ? 634 LEU   A O   1 
ATOM   4912 C CB  . LEU   A 1 608 ? 203.363 124.896 136.138 1.00 171.11 ? 634 LEU   A CB  1 
ATOM   4913 C CG  . LEU   A 1 608 ? 203.404 124.439 137.606 1.00 170.87 ? 634 LEU   A CG  1 
ATOM   4914 C CD1 . LEU   A 1 608 ? 202.026 123.937 138.019 1.00 168.53 ? 634 LEU   A CD1 1 
ATOM   4915 C CD2 . LEU   A 1 608 ? 204.465 123.372 137.864 1.00 170.77 ? 634 LEU   A CD2 1 
ATOM   4916 N N   . PRO   A 1 609 ? 204.687 127.855 136.371 1.00 172.33 ? 635 PRO   A N   1 
ATOM   4917 C CA  . PRO   A 1 609 ? 205.096 128.828 137.379 1.00 173.66 ? 635 PRO   A CA  1 
ATOM   4918 C C   . PRO   A 1 609 ? 204.628 128.393 138.754 1.00 175.24 ? 635 PRO   A C   1 
ATOM   4919 O O   . PRO   A 1 609 ? 203.619 127.675 138.883 1.00 173.74 ? 635 PRO   A O   1 
ATOM   4920 C CB  . PRO   A 1 609 ? 204.400 130.120 136.929 1.00 172.27 ? 635 PRO   A CB  1 
ATOM   4921 C CG  . PRO   A 1 609 ? 204.149 129.943 135.495 1.00 170.62 ? 635 PRO   A CG  1 
ATOM   4922 C CD  . PRO   A 1 609 ? 203.875 128.490 135.315 1.00 171.03 ? 635 PRO   A CD  1 
ATOM   4923 N N   . PRO   A 1 610 ? 205.343 128.788 139.816 1.00 177.41 ? 636 PRO   A N   1 
ATOM   4924 C CA  . PRO   A 1 610 ? 204.905 128.384 141.163 1.00 176.14 ? 636 PRO   A CA  1 
ATOM   4925 C C   . PRO   A 1 610 ? 203.525 128.898 141.526 1.00 176.17 ? 636 PRO   A C   1 
ATOM   4926 O O   . PRO   A 1 610 ? 202.789 128.218 142.252 1.00 175.71 ? 636 PRO   A O   1 
ATOM   4927 C CB  . PRO   A 1 610 ? 205.989 128.976 142.075 1.00 175.74 ? 636 PRO   A CB  1 
ATOM   4928 C CG  . PRO   A 1 610 ? 206.520 130.132 141.320 1.00 175.50 ? 636 PRO   A CG  1 
ATOM   4929 C CD  . PRO   A 1 610 ? 206.473 129.733 139.875 1.00 176.60 ? 636 PRO   A CD  1 
ATOM   4930 N N   . GLU   A 1 611 ? 203.150 130.085 141.041 1.00 175.28 ? 637 GLU   A N   1 
ATOM   4931 C CA  . GLU   A 1 611 ? 201.811 130.603 141.301 1.00 172.83 ? 637 GLU   A CA  1 
ATOM   4932 C C   . GLU   A 1 611 ? 200.739 129.748 140.637 1.00 171.88 ? 637 GLU   A C   1 
ATOM   4933 O O   . GLU   A 1 611 ? 199.595 129.721 141.103 1.00 169.38 ? 637 GLU   A O   1 
ATOM   4934 C CB  . GLU   A 1 611 ? 201.703 132.050 140.817 1.00 169.98 ? 637 GLU   A CB  1 
ATOM   4935 C CG  . GLU   A 1 611 ? 202.686 133.014 141.474 1.00 169.23 ? 637 GLU   A CG  1 
ATOM   4936 C CD  . GLU   A 1 611 ? 202.450 133.178 142.965 1.00 165.81 ? 637 GLU   A CD  1 
ATOM   4937 O OE1 . GLU   A 1 611 ? 201.367 132.783 143.447 1.00 164.25 ? 637 GLU   A OE1 1 
ATOM   4938 O OE2 . GLU   A 1 611 ? 203.348 133.703 143.655 1.00 163.45 ? 637 GLU   A OE2 1 
ATOM   4939 N N   . LEU   A 1 612 ? 201.081 129.058 139.546 1.00 171.74 ? 638 LEU   A N   1 
ATOM   4940 C CA  . LEU   A 1 612 ? 200.123 128.178 138.889 1.00 171.22 ? 638 LEU   A CA  1 
ATOM   4941 C C   . LEU   A 1 612 ? 199.911 126.876 139.654 1.00 173.10 ? 638 LEU   A C   1 
ATOM   4942 O O   . LEU   A 1 612 ? 198.891 126.212 139.444 1.00 172.44 ? 638 LEU   A O   1 
ATOM   4943 C CB  . LEU   A 1 612 ? 200.585 127.877 137.461 1.00 169.60 ? 638 LEU   A CB  1 
ATOM   4944 C CG  . LEU   A 1 612 ? 199.515 127.363 136.491 1.00 167.15 ? 638 LEU   A CG  1 
ATOM   4945 C CD1 . LEU   A 1 612 ? 199.668 128.035 135.135 1.00 161.36 ? 638 LEU   A CD1 1 
ATOM   4946 C CD2 . LEU   A 1 612 ? 199.578 125.851 136.337 1.00 166.57 ? 638 LEU   A CD2 1 
ATOM   4947 N N   . GLN   A 1 613 ? 200.849 126.489 140.520 1.00 175.37 ? 639 GLN   A N   1 
ATOM   4948 C CA  . GLN   A 1 613 ? 200.693 125.241 141.266 1.00 175.09 ? 639 GLN   A CA  1 
ATOM   4949 C C   . GLN   A 1 613 ? 199.459 125.245 142.161 1.00 175.69 ? 639 GLN   A C   1 
ATOM   4950 O O   . GLN   A 1 613 ? 198.741 124.229 142.185 1.00 174.81 ? 639 GLN   A O   1 
ATOM   4951 C CB  . GLN   A 1 613 ? 201.975 124.957 142.058 1.00 174.70 ? 639 GLN   A CB  1 
ATOM   4952 C CG  . GLN   A 1 613 ? 203.145 124.526 141.194 1.00 175.08 ? 639 GLN   A CG  1 
ATOM   4953 C CD  . GLN   A 1 613 ? 204.434 124.402 141.981 1.00 172.92 ? 639 GLN   A CD  1 
ATOM   4954 O OE1 . GLN   A 1 613 ? 204.418 124.285 143.206 1.00 172.16 ? 639 GLN   A OE1 1 
ATOM   4955 N NE2 . GLN   A 1 613 ? 205.561 124.435 141.279 1.00 170.19 ? 639 GLN   A NE2 1 
ATOM   4956 N N   . PRO   A 1 614 ? 199.159 126.306 142.921 1.00 176.57 ? 640 PRO   A N   1 
ATOM   4957 C CA  . PRO   A 1 614 ? 197.873 126.342 143.637 1.00 175.05 ? 640 PRO   A CA  1 
ATOM   4958 C C   . PRO   A 1 614 ? 196.659 126.200 142.737 1.00 172.52 ? 640 PRO   A C   1 
ATOM   4959 O O   . PRO   A 1 614 ? 195.652 125.625 143.169 1.00 173.55 ? 640 PRO   A O   1 
ATOM   4960 C CB  . PRO   A 1 614 ? 197.895 127.716 144.320 1.00 172.71 ? 640 PRO   A CB  1 
ATOM   4961 C CG  . PRO   A 1 614 ? 199.319 128.002 144.538 1.00 172.57 ? 640 PRO   A CG  1 
ATOM   4962 C CD  . PRO   A 1 614 ? 200.087 127.334 143.429 1.00 174.76 ? 640 PRO   A CD  1 
ATOM   4963 N N   . LEU   A 1 615 ? 196.710 126.717 141.506 1.00 170.09 ? 641 LEU   A N   1 
ATOM   4964 C CA  . LEU   A 1 615 ? 195.560 126.602 140.615 1.00 170.06 ? 641 LEU   A CA  1 
ATOM   4965 C C   . LEU   A 1 615 ? 195.263 125.143 140.291 1.00 171.97 ? 641 LEU   A C   1 
ATOM   4966 O O   . LEU   A 1 615 ? 194.110 124.702 140.362 1.00 171.65 ? 641 LEU   A O   1 
ATOM   4967 C CB  . LEU   A 1 615 ? 195.804 127.398 139.331 1.00 166.51 ? 641 LEU   A CB  1 
ATOM   4968 C CG  . LEU   A 1 615 ? 195.878 128.920 139.480 1.00 161.11 ? 641 LEU   A CG  1 
ATOM   4969 C CD1 . LEU   A 1 615 ? 196.368 129.570 138.196 1.00 155.55 ? 641 LEU   A CD1 1 
ATOM   4970 C CD2 . LEU   A 1 615 ? 194.522 129.487 139.868 1.00 156.99 ? 641 LEU   A CD2 1 
ATOM   4971 N N   . LEU   A 1 616 ? 196.294 124.377 139.931 1.00 170.98 ? 642 LEU   A N   1 
ATOM   4972 C CA  . LEU   A 1 616 ? 196.094 122.953 139.690 1.00 171.04 ? 642 LEU   A CA  1 
ATOM   4973 C C   . LEU   A 1 616 ? 195.699 122.230 140.970 1.00 174.81 ? 642 LEU   A C   1 
ATOM   4974 O O   . LEU   A 1 616 ? 194.805 121.375 140.955 1.00 175.86 ? 642 LEU   A O   1 
ATOM   4975 C CB  . LEU   A 1 616 ? 197.359 122.335 139.094 1.00 169.43 ? 642 LEU   A CB  1 
ATOM   4976 C CG  . LEU   A 1 616 ? 197.871 122.922 137.775 1.00 167.77 ? 642 LEU   A CG  1 
ATOM   4977 C CD1 . LEU   A 1 616 ? 199.121 122.183 137.328 1.00 165.69 ? 642 LEU   A CD1 1 
ATOM   4978 C CD2 . LEU   A 1 616 ? 196.808 122.873 136.684 1.00 164.03 ? 642 LEU   A CD2 1 
ATOM   4979 N N   . GLU   A 1 617 ? 196.354 122.554 142.088 1.00 177.34 ? 643 GLU   A N   1 
ATOM   4980 C CA  . GLU   A 1 617 ? 196.005 121.918 143.355 1.00 177.94 ? 643 GLU   A CA  1 
ATOM   4981 C C   . GLU   A 1 617 ? 194.590 122.284 143.786 1.00 179.87 ? 643 GLU   A C   1 
ATOM   4982 O O   . GLU   A 1 617 ? 193.833 121.422 144.248 1.00 180.15 ? 643 GLU   A O   1 
ATOM   4983 C CB  . GLU   A 1 617 ? 197.012 122.313 144.435 1.00 176.56 ? 643 GLU   A CB  1 
ATOM   4984 C CG  . GLU   A 1 617 ? 198.397 121.719 144.237 1.00 175.06 ? 643 GLU   A CG  1 
ATOM   4985 C CD  . GLU   A 1 617 ? 199.383 122.177 145.293 1.00 173.27 ? 643 GLU   A CD  1 
ATOM   4986 O OE1 . GLU   A 1 617 ? 198.973 122.925 146.206 1.00 173.16 ? 643 GLU   A OE1 1 
ATOM   4987 O OE2 . GLU   A 1 617 ? 200.568 121.791 145.210 1.00 169.08 ? 643 GLU   A OE2 1 
ATOM   4988 N N   . GLY   A 1 618 ? 194.215 123.553 143.642 1.00 180.14 ? 644 GLY   A N   1 
ATOM   4989 C CA  . GLY   A 1 618 ? 192.892 124.012 144.006 1.00 179.56 ? 644 GLY   A CA  1 
ATOM   4990 C C   . GLY   A 1 618 ? 192.685 124.296 145.477 1.00 182.39 ? 644 GLY   A C   1 
ATOM   4991 O O   . GLY   A 1 618 ? 191.578 124.700 145.858 1.00 179.48 ? 644 GLY   A O   1 
ATOM   4992 N N   . GLU   A 1 619 ? 193.703 124.098 146.317 1.00 186.32 ? 645 GLU   A N   1 
ATOM   4993 C CA  . GLU   A 1 619 ? 193.603 124.340 147.751 1.00 187.28 ? 645 GLU   A CA  1 
ATOM   4994 C C   . GLU   A 1 619 ? 194.863 125.044 148.227 1.00 187.23 ? 645 GLU   A C   1 
ATOM   4995 O O   . GLU   A 1 619 ? 195.975 124.637 147.877 1.00 186.17 ? 645 GLU   A O   1 
ATOM   4996 C CB  . GLU   A 1 619 ? 193.402 123.030 148.522 1.00 186.16 ? 645 GLU   A CB  1 
ATOM   4997 C CG  . GLU   A 1 619 ? 192.108 122.308 148.181 1.00 184.13 ? 645 GLU   A CG  1 
ATOM   4998 C CD  . GLU   A 1 619 ? 191.921 121.035 148.982 1.00 181.47 ? 645 GLU   A CD  1 
ATOM   4999 O OE1 . GLU   A 1 619 ? 192.817 120.697 149.783 1.00 180.59 ? 645 GLU   A OE1 1 
ATOM   5000 O OE2 . GLU   A 1 619 ? 190.875 120.373 148.812 1.00 181.35 ? 645 GLU   A OE2 1 
ATOM   5001 N N   . VAL   A 1 620 ? 194.684 126.096 149.025 1.00 186.56 ? 646 VAL   A N   1 
ATOM   5002 C CA  . VAL   A 1 620 ? 195.803 126.880 149.555 1.00 184.95 ? 646 VAL   A CA  1 
ATOM   5003 C C   . VAL   A 1 620 ? 196.207 126.215 150.867 1.00 185.74 ? 646 VAL   A C   1 
ATOM   5004 O O   . VAL   A 1 620 ? 195.739 126.580 151.947 1.00 183.40 ? 646 VAL   A O   1 
ATOM   5005 C CB  . VAL   A 1 620 ? 195.435 128.352 149.739 1.00 181.01 ? 646 VAL   A CB  1 
ATOM   5006 C CG1 . VAL   A 1 620 ? 196.637 129.150 150.249 1.00 176.85 ? 646 VAL   A CG1 1 
ATOM   5007 C CG2 . VAL   A 1 620 ? 194.912 128.944 148.435 1.00 176.78 ? 646 VAL   A CG2 1 
ATOM   5008 N N   . LYS   A 1 621 ? 197.088 125.221 150.769 1.00 188.30 ? 647 LYS   A N   1 
ATOM   5009 C CA  . LYS   A 1 621 ? 197.614 124.513 151.928 1.00 188.24 ? 647 LYS   A CA  1 
ATOM   5010 C C   . LYS   A 1 621 ? 199.117 124.348 151.770 1.00 190.87 ? 647 LYS   A C   1 
ATOM   5011 O O   . LYS   A 1 621 ? 199.589 123.898 150.720 1.00 191.85 ? 647 LYS   A O   1 
ATOM   5012 C CB  . LYS   A 1 621 ? 196.940 123.146 152.092 1.00 186.13 ? 647 LYS   A CB  1 
ATOM   5013 C CG  . LYS   A 1 621 ? 195.429 123.226 152.257 1.00 184.39 ? 647 LYS   A CG  1 
ATOM   5014 C CD  . LYS   A 1 621 ? 194.808 121.850 152.419 1.00 182.36 ? 647 LYS   A CD  1 
ATOM   5015 C CE  . LYS   A 1 621 ? 193.298 121.939 152.563 1.00 181.85 ? 647 LYS   A CE  1 
ATOM   5016 N NZ  . LYS   A 1 621 ? 192.673 120.597 152.713 1.00 180.79 ? 647 LYS   A NZ  1 
ATOM   5017 N N   . GLY   A 1 622 ? 199.861 124.708 152.811 1.00 190.34 ? 648 GLY   A N   1 
ATOM   5018 C CA  . GLY   A 1 622 ? 201.307 124.548 152.795 1.00 188.31 ? 648 GLY   A CA  1 
ATOM   5019 C C   . GLY   A 1 622 ? 202.005 125.334 151.707 1.00 189.03 ? 648 GLY   A C   1 
ATOM   5020 O O   . GLY   A 1 622 ? 202.912 124.808 151.050 1.00 187.80 ? 648 GLY   A O   1 
ATOM   5021 N N   . GLY   A 1 623 ? 201.604 126.586 151.498 1.00 189.15 ? 649 GLY   A N   1 
ATOM   5022 C CA  . GLY   A 1 623 ? 202.213 127.414 150.485 1.00 185.49 ? 649 GLY   A CA  1 
ATOM   5023 C C   . GLY   A 1 623 ? 201.872 128.882 150.643 1.00 182.34 ? 649 GLY   A C   1 
ATOM   5024 O O   . GLY   A 1 623 ? 201.077 129.270 151.505 1.00 179.92 ? 649 GLY   A O   1 
ATOM   5025 N N   . PRO   A 1 624 ? 202.473 129.731 149.810 1.00 181.42 ? 650 PRO   A N   1 
ATOM   5026 C CA  . PRO   A 1 624 ? 202.190 131.168 149.894 1.00 179.19 ? 650 PRO   A CA  1 
ATOM   5027 C C   . PRO   A 1 624 ? 200.749 131.481 149.525 1.00 177.60 ? 650 PRO   A C   1 
ATOM   5028 O O   . PRO   A 1 624 ? 200.110 130.766 148.750 1.00 177.31 ? 650 PRO   A O   1 
ATOM   5029 C CB  . PRO   A 1 624 ? 203.170 131.784 148.890 1.00 176.28 ? 650 PRO   A CB  1 
ATOM   5030 C CG  . PRO   A 1 624 ? 203.455 130.693 147.923 1.00 176.44 ? 650 PRO   A CG  1 
ATOM   5031 C CD  . PRO   A 1 624 ? 203.402 129.416 148.709 1.00 178.43 ? 650 PRO   A CD  1 
ATOM   5032 N N   . GLU   A 1 625 ? 200.239 132.563 150.105 1.00 175.00 ? 651 GLU   A N   1 
ATOM   5033 C CA  . GLU   A 1 625 ? 198.870 132.970 149.830 1.00 171.50 ? 651 GLU   A CA  1 
ATOM   5034 C C   . GLU   A 1 625 ? 198.725 133.343 148.353 1.00 170.86 ? 651 GLU   A C   1 
ATOM   5035 O O   . GLU   A 1 625 ? 199.622 133.979 147.787 1.00 171.32 ? 651 GLU   A O   1 
ATOM   5036 C CB  . GLU   A 1 625 ? 198.477 134.158 150.709 1.00 169.15 ? 651 GLU   A CB  1 
ATOM   5037 C CG  . GLU   A 1 625 ? 198.530 133.874 152.201 1.00 168.59 ? 651 GLU   A CG  1 
ATOM   5038 C CD  . GLU   A 1 625 ? 198.124 135.073 153.035 1.00 166.63 ? 651 GLU   A CD  1 
ATOM   5039 O OE1 . GLU   A 1 625 ? 197.797 136.125 152.447 1.00 166.23 ? 651 GLU   A OE1 1 
ATOM   5040 O OE2 . GLU   A 1 625 ? 198.132 134.963 154.279 1.00 164.01 ? 651 GLU   A OE2 1 
ATOM   5041 N N   . PRO   A 1 626 ? 197.625 132.968 147.693 1.00 168.79 ? 652 PRO   A N   1 
ATOM   5042 C CA  . PRO   A 1 626 ? 197.475 133.322 146.278 1.00 163.27 ? 652 PRO   A CA  1 
ATOM   5043 C C   . PRO   A 1 626 ? 197.309 134.820 146.078 1.00 160.47 ? 652 PRO   A C   1 
ATOM   5044 O O   . PRO   A 1 626 ? 196.835 135.543 146.958 1.00 160.92 ? 652 PRO   A O   1 
ATOM   5045 C CB  . PRO   A 1 626 ? 196.210 132.567 145.855 1.00 159.76 ? 652 PRO   A CB  1 
ATOM   5046 C CG  . PRO   A 1 626 ? 195.427 132.444 147.095 1.00 161.68 ? 652 PRO   A CG  1 
ATOM   5047 C CD  . PRO   A 1 626 ? 196.435 132.249 148.187 1.00 167.12 ? 652 PRO   A CD  1 
ATOM   5048 N N   . THR   A 1 627 ? 197.711 135.282 144.897 1.00 155.77 ? 653 THR   A N   1 
ATOM   5049 C CA  . THR   A 1 627 ? 197.504 136.670 144.532 1.00 151.24 ? 653 THR   A CA  1 
ATOM   5050 C C   . THR   A 1 627 ? 196.009 136.939 144.360 1.00 148.94 ? 653 THR   A C   1 
ATOM   5051 O O   . THR   A 1 627 ? 195.220 136.003 144.211 1.00 149.70 ? 653 THR   A O   1 
ATOM   5052 C CB  . THR   A 1 627 ? 198.248 137.004 143.241 1.00 149.87 ? 653 THR   A CB  1 
ATOM   5053 O OG1 . THR   A 1 627 ? 197.780 136.158 142.183 1.00 149.20 ? 653 THR   A OG1 1 
ATOM   5054 C CG2 . THR   A 1 627 ? 199.748 136.811 143.418 1.00 151.00 ? 653 THR   A CG2 1 
ATOM   5055 N N   . PRO   A 1 628 ? 195.588 138.211 144.403 1.00 144.68 ? 654 PRO   A N   1 
ATOM   5056 C CA  . PRO   A 1 628 ? 194.155 138.504 144.212 1.00 141.83 ? 654 PRO   A CA  1 
ATOM   5057 C C   . PRO   A 1 628 ? 193.601 137.996 142.893 1.00 140.74 ? 654 PRO   A C   1 
ATOM   5058 O O   . PRO   A 1 628 ? 192.428 137.608 142.832 1.00 139.83 ? 654 PRO   A O   1 
ATOM   5059 C CB  . PRO   A 1 628 ? 194.098 140.037 144.288 1.00 139.26 ? 654 PRO   A CB  1 
ATOM   5060 C CG  . PRO   A 1 628 ? 195.298 140.428 145.051 1.00 139.67 ? 654 PRO   A CG  1 
ATOM   5061 C CD  . PRO   A 1 628 ? 196.357 139.432 144.701 1.00 143.06 ? 654 PRO   A CD  1 
ATOM   5062 N N   . LEU   A 1 629 ? 194.411 137.988 141.832 1.00 138.30 ? 655 LEU   A N   1 
ATOM   5063 C CA  . LEU   A 1 629 ? 193.954 137.448 140.556 1.00 136.02 ? 655 LEU   A CA  1 
ATOM   5064 C C   . LEU   A 1 629 ? 193.635 135.963 140.676 1.00 137.27 ? 655 LEU   A C   1 
ATOM   5065 O O   . LEU   A 1 629 ? 192.615 135.491 140.156 1.00 137.62 ? 655 LEU   A O   1 
ATOM   5066 C CB  . LEU   A 1 629 ? 195.018 137.691 139.485 1.00 132.43 ? 655 LEU   A CB  1 
ATOM   5067 C CG  . LEU   A 1 629 ? 194.552 137.802 138.030 1.00 130.93 ? 655 LEU   A CG  1 
ATOM   5068 C CD1 . LEU   A 1 629 ? 195.684 138.338 137.164 1.00 124.61 ? 655 LEU   A CD1 1 
ATOM   5069 C CD2 . LEU   A 1 629 ? 194.052 136.471 137.484 1.00 130.33 ? 655 LEU   A CD2 1 
ATOM   5070 N N   . VAL   A 1 630 ? 194.495 135.210 141.363 1.00 138.67 ? 656 VAL   A N   1 
ATOM   5071 C CA  . VAL   A 1 630 ? 194.258 133.781 141.542 1.00 142.14 ? 656 VAL   A CA  1 
ATOM   5072 C C   . VAL   A 1 630 ? 193.002 133.554 142.372 1.00 142.58 ? 656 VAL   A C   1 
ATOM   5073 O O   . VAL   A 1 630 ? 192.209 132.644 142.092 1.00 141.32 ? 656 VAL   A O   1 
ATOM   5074 C CB  . VAL   A 1 630 ? 195.494 133.118 142.177 1.00 145.70 ? 656 VAL   A CB  1 
ATOM   5075 C CG1 . VAL   A 1 630 ? 195.177 131.695 142.624 1.00 145.88 ? 656 VAL   A CG1 1 
ATOM   5076 C CG2 . VAL   A 1 630 ? 196.661 133.129 141.201 1.00 146.47 ? 656 VAL   A CG2 1 
ATOM   5077 N N   . GLN   A 1 631 ? 192.808 134.367 143.413 1.00 143.19 ? 657 GLN   A N   1 
ATOM   5078 C CA  . GLN   A 1 631 ? 191.594 134.265 144.216 1.00 144.64 ? 657 GLN   A CA  1 
ATOM   5079 C C   . GLN   A 1 631 ? 190.358 134.533 143.371 1.00 140.34 ? 657 GLN   A C   1 
ATOM   5080 O O   . GLN   A 1 631 ? 189.343 133.836 143.499 1.00 139.10 ? 657 GLN   A O   1 
ATOM   5081 C CB  . GLN   A 1 631 ? 191.659 135.240 145.391 1.00 144.00 ? 657 GLN   A CB  1 
ATOM   5082 C CG  . GLN   A 1 631 ? 192.779 134.952 146.377 1.00 147.47 ? 657 GLN   A CG  1 
ATOM   5083 C CD  . GLN   A 1 631 ? 192.823 135.953 147.514 1.00 147.60 ? 657 GLN   A CD  1 
ATOM   5084 O OE1 . GLN   A 1 631 ? 191.955 136.818 147.629 1.00 145.84 ? 657 GLN   A OE1 1 
ATOM   5085 N NE2 . GLN   A 1 631 ? 193.839 135.841 148.361 1.00 150.57 ? 657 GLN   A NE2 1 
ATOM   5086 N N   . THR   A 1 632 ? 190.423 135.545 142.502 1.00 135.91 ? 658 THR   A N   1 
ATOM   5087 C CA  . THR   A 1 632 ? 189.298 135.838 141.624 1.00 136.27 ? 658 THR   A CA  1 
ATOM   5088 C C   . THR   A 1 632 ? 189.022 134.673 140.683 1.00 136.49 ? 658 THR   A C   1 
ATOM   5089 O O   . THR   A 1 632 ? 187.860 134.333 140.431 1.00 136.39 ? 658 THR   A O   1 
ATOM   5090 C CB  . THR   A 1 632 ? 189.573 137.115 140.830 1.00 134.87 ? 658 THR   A CB  1 
ATOM   5091 O OG1 . THR   A 1 632 ? 189.816 138.201 141.733 1.00 133.86 ? 658 THR   A OG1 1 
ATOM   5092 C CG2 . THR   A 1 632 ? 188.389 137.460 139.934 1.00 129.16 ? 658 THR   A CG2 1 
ATOM   5093 N N   . PHE   A 1 633 ? 190.077 134.054 140.148 1.00 134.67 ? 659 PHE   A N   1 
ATOM   5094 C CA  . PHE   A 1 633 ? 189.885 132.912 139.258 1.00 134.02 ? 659 PHE   A CA  1 
ATOM   5095 C C   . PHE   A 1 633 ? 189.222 131.751 139.987 1.00 133.49 ? 659 PHE   A C   1 
ATOM   5096 O O   . PHE   A 1 633 ? 188.299 131.118 139.457 1.00 133.13 ? 659 PHE   A O   1 
ATOM   5097 C CB  . PHE   A 1 633 ? 191.223 132.470 138.666 1.00 134.75 ? 659 PHE   A CB  1 
ATOM   5098 C CG  . PHE   A 1 633 ? 191.115 131.290 137.738 1.00 135.74 ? 659 PHE   A CG  1 
ATOM   5099 C CD1 . PHE   A 1 633 ? 190.778 131.468 136.407 1.00 131.17 ? 659 PHE   A CD1 1 
ATOM   5100 C CD2 . PHE   A 1 633 ? 191.355 130.005 138.194 1.00 137.39 ? 659 PHE   A CD2 1 
ATOM   5101 C CE1 . PHE   A 1 633 ? 190.678 130.388 135.550 1.00 127.17 ? 659 PHE   A CE1 1 
ATOM   5102 C CE2 . PHE   A 1 633 ? 191.256 128.922 137.342 1.00 135.49 ? 659 PHE   A CE2 1 
ATOM   5103 C CZ  . PHE   A 1 633 ? 190.917 129.115 136.019 1.00 131.48 ? 659 PHE   A CZ  1 
ATOM   5104 N N   . LEU   A 1 634 ? 189.687 131.449 141.201 1.00 134.65 ? 660 LEU   A N   1 
ATOM   5105 C CA  . LEU   A 1 634 ? 189.084 130.362 141.966 1.00 138.67 ? 660 LEU   A CA  1 
ATOM   5106 C C   . LEU   A 1 634 ? 187.627 130.665 142.292 1.00 135.80 ? 660 LEU   A C   1 
ATOM   5107 O O   . LEU   A 1 634 ? 186.767 129.778 142.218 1.00 134.02 ? 660 LEU   A O   1 
ATOM   5108 C CB  . LEU   A 1 634 ? 189.882 130.113 143.248 1.00 143.83 ? 660 LEU   A CB  1 
ATOM   5109 C CG  . LEU   A 1 634 ? 191.316 129.594 143.087 1.00 146.13 ? 660 LEU   A CG  1 
ATOM   5110 C CD1 . LEU   A 1 634 ? 192.011 129.535 144.439 1.00 145.07 ? 660 LEU   A CD1 1 
ATOM   5111 C CD2 . LEU   A 1 634 ? 191.343 128.227 142.416 1.00 146.10 ? 660 LEU   A CD2 1 
ATOM   5112 N N   . ARG   A 1 635 ? 187.331 131.916 142.654 1.00 133.59 ? 661 ARG   A N   1 
ATOM   5113 C CA  . ARG   A 1 635 ? 185.953 132.295 142.941 1.00 133.06 ? 661 ARG   A CA  1 
ATOM   5114 C C   . ARG   A 1 635 ? 185.076 132.144 141.706 1.00 130.66 ? 661 ARG   A C   1 
ATOM   5115 O O   . ARG   A 1 635 ? 183.942 131.658 141.797 1.00 133.33 ? 661 ARG   A O   1 
ATOM   5116 C CB  . ARG   A 1 635 ? 185.908 133.732 143.465 1.00 136.48 ? 661 ARG   A CB  1 
ATOM   5117 C CG  . ARG   A 1 635 ? 184.539 134.179 143.968 1.00 137.46 ? 661 ARG   A CG  1 
ATOM   5118 C CD  . ARG   A 1 635 ? 184.544 135.628 144.444 1.00 137.83 ? 661 ARG   A CD  1 
ATOM   5119 N NE  . ARG   A 1 635 ? 185.336 135.826 145.656 1.00 140.54 ? 661 ARG   A NE  1 
ATOM   5120 C CZ  . ARG   A 1 635 ? 186.622 136.158 145.697 1.00 140.35 ? 661 ARG   A CZ  1 
ATOM   5121 N NH1 . ARG   A 1 635 ? 187.339 136.327 144.595 1.00 138.87 ? 661 ARG   A NH1 1 
ATOM   5122 N NH2 . ARG   A 1 635 ? 187.209 136.323 146.879 1.00 139.09 ? 661 ARG   A NH2 1 
ATOM   5123 N N   . ARG   A 1 636 ? 185.579 132.562 140.543 1.00 126.15 ? 662 ARG   A N   1 
ATOM   5124 C CA  . ARG   A 1 636 ? 184.808 132.425 139.313 1.00 127.62 ? 662 ARG   A CA  1 
ATOM   5125 C C   . ARG   A 1 636 ? 184.548 130.959 138.992 1.00 131.24 ? 662 ARG   A C   1 
ATOM   5126 O O   . ARG   A 1 636 ? 183.437 130.592 138.591 1.00 131.49 ? 662 ARG   A O   1 
ATOM   5127 C CB  . ARG   A 1 636 ? 185.539 133.108 138.156 1.00 130.77 ? 662 ARG   A CB  1 
ATOM   5128 C CG  . ARG   A 1 636 ? 184.750 133.146 136.851 1.00 134.25 ? 662 ARG   A CG  1 
ATOM   5129 C CD  . ARG   A 1 636 ? 185.481 133.932 135.774 1.00 132.52 ? 662 ARG   A CD  1 
ATOM   5130 N NE  . ARG   A 1 636 ? 184.745 133.946 134.515 1.00 132.09 ? 662 ARG   A NE  1 
ATOM   5131 C CZ  . ARG   A 1 636 ? 185.150 134.549 133.404 1.00 131.06 ? 662 ARG   A CZ  1 
ATOM   5132 N NH1 . ARG   A 1 636 ? 186.296 135.211 133.347 1.00 126.85 ? 662 ARG   A NH1 1 
ATOM   5133 N NH2 . ARG   A 1 636 ? 184.384 134.487 132.318 1.00 130.80 ? 662 ARG   A NH2 1 
ATOM   5134 N N   . GLN   A 1 637 ? 185.562 130.106 139.157 1.00 132.11 ? 663 GLN   A N   1 
ATOM   5135 C CA  . GLN   A 1 637 ? 185.377 128.682 138.893 1.00 129.79 ? 663 GLN   A CA  1 
ATOM   5136 C C   . GLN   A 1 637 ? 184.347 128.076 139.838 1.00 128.32 ? 663 GLN   A C   1 
ATOM   5137 O O   . GLN   A 1 637 ? 183.484 127.296 139.414 1.00 127.31 ? 663 GLN   A O   1 
ATOM   5138 C CB  . GLN   A 1 637 ? 186.714 127.949 139.018 1.00 129.43 ? 663 GLN   A CB  1 
ATOM   5139 C CG  . GLN   A 1 637 ? 186.660 126.472 138.647 1.00 128.55 ? 663 GLN   A CG  1 
ATOM   5140 C CD  . GLN   A 1 637 ? 188.024 125.813 138.689 1.00 131.67 ? 663 GLN   A CD  1 
ATOM   5141 O OE1 . GLN   A 1 637 ? 189.037 126.471 138.926 1.00 133.63 ? 663 GLN   A OE1 1 
ATOM   5142 N NE2 . GLN   A 1 637 ? 188.057 124.506 138.459 1.00 128.81 ? 663 GLN   A NE2 1 
ATOM   5143 N N   . GLN   A 1 638 ? 184.417 128.430 141.124 1.00 129.31 ? 664 GLN   A N   1 
ATOM   5144 C CA  . GLN   A 1 638 ? 183.450 127.912 142.085 1.00 129.47 ? 664 GLN   A CA  1 
ATOM   5145 C C   . GLN   A 1 638 ? 182.039 128.377 141.749 1.00 127.92 ? 664 GLN   A C   1 
ATOM   5146 O O   . GLN   A 1 638 ? 181.086 127.593 141.820 1.00 124.14 ? 664 GLN   A O   1 
ATOM   5147 C CB  . GLN   A 1 638 ? 183.839 128.345 143.499 1.00 131.98 ? 664 GLN   A CB  1 
ATOM   5148 C CG  . GLN   A 1 638 ? 182.984 127.734 144.601 1.00 134.25 ? 664 GLN   A CG  1 
ATOM   5149 C CD  . GLN   A 1 638 ? 183.479 128.094 145.988 1.00 134.43 ? 664 GLN   A CD  1 
ATOM   5150 O OE1 . GLN   A 1 638 ? 184.516 128.739 146.142 1.00 133.32 ? 664 GLN   A OE1 1 
ATOM   5151 N NE2 . GLN   A 1 638 ? 182.736 127.679 147.008 1.00 133.90 ? 664 GLN   A NE2 1 
ATOM   5152 N N   . ARG   A 1 639 ? 181.885 129.653 141.388 1.00 129.13 ? 665 ARG   A N   1 
ATOM   5153 C CA  . ARG   A 1 639 ? 180.566 130.169 141.037 1.00 127.74 ? 665 ARG   A CA  1 
ATOM   5154 C C   . ARG   A 1 639 ? 180.017 129.476 139.796 1.00 129.20 ? 665 ARG   A C   1 
ATOM   5155 O O   . ARG   A 1 639 ? 178.823 129.156 139.731 1.00 129.52 ? 665 ARG   A O   1 
ATOM   5156 C CB  . ARG   A 1 639 ? 180.637 131.680 140.823 1.00 131.16 ? 665 ARG   A CB  1 
ATOM   5157 C CG  . ARG   A 1 639 ? 179.281 132.359 140.700 1.00 133.56 ? 665 ARG   A CG  1 
ATOM   5158 C CD  . ARG   A 1 639 ? 179.426 133.862 140.521 1.00 135.56 ? 665 ARG   A CD  1 
ATOM   5159 N NE  . ARG   A 1 639 ? 178.131 134.530 140.426 1.00 139.21 ? 665 ARG   A NE  1 
ATOM   5160 C CZ  . ARG   A 1 639 ? 177.369 134.872 141.458 1.00 139.02 ? 665 ARG   A CZ  1 
ATOM   5161 N NH1 . ARG   A 1 639 ? 177.728 134.615 142.707 1.00 138.71 ? 665 ARG   A NH1 1 
ATOM   5162 N NH2 . ARG   A 1 639 ? 176.212 135.487 141.231 1.00 136.77 ? 665 ARG   A NH2 1 
ATOM   5163 N N   . LEU   A 1 640 ? 180.870 129.246 138.794 1.00 130.66 ? 666 LEU   A N   1 
ATOM   5164 C CA  . LEU   A 1 640 ? 180.422 128.552 137.592 1.00 131.09 ? 666 LEU   A CA  1 
ATOM   5165 C C   . LEU   A 1 640 ? 179.986 127.129 137.915 1.00 127.07 ? 666 LEU   A C   1 
ATOM   5166 O O   . LEU   A 1 640 ? 178.964 126.653 137.405 1.00 125.63 ? 666 LEU   A O   1 
ATOM   5167 C CB  . LEU   A 1 640 ? 181.536 128.551 136.544 1.00 133.32 ? 666 LEU   A CB  1 
ATOM   5168 C CG  . LEU   A 1 640 ? 181.233 127.909 135.185 1.00 133.70 ? 666 LEU   A CG  1 
ATOM   5169 C CD1 . LEU   A 1 640 ? 180.065 128.599 134.493 1.00 132.40 ? 666 LEU   A CD1 1 
ATOM   5170 C CD2 . LEU   A 1 640 ? 182.470 127.939 134.301 1.00 130.23 ? 666 LEU   A CD2 1 
ATOM   5171 N N   . GLN   A 1 641 ? 180.744 126.438 138.770 1.00 123.67 ? 667 GLN   A N   1 
ATOM   5172 C CA  . GLN   A 1 641 ? 180.349 125.091 139.172 1.00 123.66 ? 667 GLN   A CA  1 
ATOM   5173 C C   . GLN   A 1 641 ? 179.022 125.111 139.918 1.00 119.94 ? 667 GLN   A C   1 
ATOM   5174 O O   . GLN   A 1 641 ? 178.173 124.235 139.715 1.00 118.34 ? 667 GLN   A O   1 
ATOM   5175 C CB  . GLN   A 1 641 ? 181.441 124.459 140.035 1.00 126.59 ? 667 GLN   A CB  1 
ATOM   5176 C CG  . GLN   A 1 641 ? 182.702 124.100 139.265 1.00 128.60 ? 667 GLN   A CG  1 
ATOM   5177 C CD  . GLN   A 1 641 ? 183.803 123.570 140.162 1.00 130.62 ? 667 GLN   A CD  1 
ATOM   5178 O OE1 . GLN   A 1 641 ? 183.587 123.317 141.347 1.00 129.90 ? 667 GLN   A OE1 1 
ATOM   5179 N NE2 . GLN   A 1 641 ? 184.995 123.402 139.600 1.00 129.24 ? 667 GLN   A NE2 1 
ATOM   5180 N N   . GLU   A 1 642 ? 178.827 126.101 140.790 1.00 120.33 ? 668 GLU   A N   1 
ATOM   5181 C CA  . GLU   A 1 642 ? 177.571 126.203 141.526 1.00 122.55 ? 668 GLU   A CA  1 
ATOM   5182 C C   . GLU   A 1 642 ? 176.397 126.435 140.582 1.00 119.41 ? 668 GLU   A C   1 
ATOM   5183 O O   . GLU   A 1 642 ? 175.330 125.833 140.746 1.00 117.99 ? 668 GLU   A O   1 
ATOM   5184 C CB  . GLU   A 1 642 ? 177.663 127.326 142.559 1.00 126.56 ? 668 GLU   A CB  1 
ATOM   5185 C CG  . GLU   A 1 642 ? 176.469 127.412 143.502 1.00 125.22 ? 668 GLU   A CG  1 
ATOM   5186 C CD  . GLU   A 1 642 ? 176.651 128.466 144.577 1.00 123.08 ? 668 GLU   A CD  1 
ATOM   5187 O OE1 . GLU   A 1 642 ? 177.707 129.133 144.585 1.00 120.63 ? 668 GLU   A OE1 1 
ATOM   5188 O OE2 . GLU   A 1 642 ? 175.739 128.627 145.414 1.00 121.27 ? 668 GLU   A OE2 1 
ATOM   5189 N N   . ILE   A 1 643 ? 176.575 127.308 139.590 1.00 121.60 ? 669 ILE   A N   1 
ATOM   5190 C CA  . ILE   A 1 643 ? 175.502 127.577 138.636 1.00 123.69 ? 669 ILE   A CA  1 
ATOM   5191 C C   . ILE   A 1 643 ? 175.190 126.324 137.826 1.00 122.43 ? 669 ILE   A C   1 
ATOM   5192 O O   . ILE   A 1 643 ? 174.021 125.997 137.583 1.00 121.64 ? 669 ILE   A O   1 
ATOM   5193 C CB  . ILE   A 1 643 ? 175.875 128.764 137.726 1.00 128.42 ? 669 ILE   A CB  1 
ATOM   5194 C CG1 . ILE   A 1 643 ? 175.938 130.064 138.539 1.00 128.38 ? 669 ILE   A CG1 1 
ATOM   5195 C CG2 . ILE   A 1 643 ? 174.868 128.896 136.577 1.00 125.51 ? 669 ILE   A CG2 1 
ATOM   5196 C CD1 . ILE   A 1 643 ? 176.666 131.199 137.842 1.00 127.85 ? 669 ILE   A CD1 1 
ATOM   5197 N N   . GLU   A 1 644 ? 176.230 125.607 137.390 1.00 121.70 ? 670 GLU   A N   1 
ATOM   5198 C CA  . GLU   A 1 644 ? 176.012 124.380 136.632 1.00 121.17 ? 670 GLU   A CA  1 
ATOM   5199 C C   . GLU   A 1 644 ? 175.281 123.340 137.472 1.00 120.74 ? 670 GLU   A C   1 
ATOM   5200 O O   . GLU   A 1 644 ? 174.390 122.642 136.973 1.00 118.18 ? 670 GLU   A O   1 
ATOM   5201 C CB  . GLU   A 1 644 ? 177.349 123.829 136.136 1.00 124.17 ? 670 GLU   A CB  1 
ATOM   5202 C CG  . GLU   A 1 644 ? 177.230 122.623 135.211 1.00 126.15 ? 670 GLU   A CG  1 
ATOM   5203 C CD  . GLU   A 1 644 ? 178.571 122.177 134.661 1.00 127.23 ? 670 GLU   A CD  1 
ATOM   5204 O OE1 . GLU   A 1 644 ? 179.594 122.809 134.998 1.00 124.28 ? 670 GLU   A OE1 1 
ATOM   5205 O OE2 . GLU   A 1 644 ? 178.601 121.193 133.892 1.00 130.07 ? 670 GLU   A OE2 1 
ATOM   5206 N N   . ARG   A 1 645 ? 175.648 123.218 138.750 1.00 120.74 ? 671 ARG   A N   1 
ATOM   5207 C CA  . ARG   A 1 645 ? 174.947 122.298 139.640 1.00 117.96 ? 671 ARG   A CA  1 
ATOM   5208 C C   . ARG   A 1 645 ? 173.490 122.707 139.812 1.00 117.38 ? 671 ARG   A C   1 
ATOM   5209 O O   . ARG   A 1 645 ? 172.597 121.853 139.851 1.00 114.27 ? 671 ARG   A O   1 
ATOM   5210 C CB  . ARG   A 1 645 ? 175.652 122.244 140.996 1.00 116.09 ? 671 ARG   A CB  1 
ATOM   5211 C CG  . ARG   A 1 645 ? 175.097 121.195 141.950 1.00 118.21 ? 671 ARG   A CG  1 
ATOM   5212 C CD  . ARG   A 1 645 ? 175.887 121.151 143.247 1.00 122.18 ? 671 ARG   A CD  1 
ATOM   5213 N NE  . ARG   A 1 645 ? 175.317 120.210 144.205 1.00 126.28 ? 671 ARG   A NE  1 
ATOM   5214 C CZ  . ARG   A 1 645 ? 175.788 119.990 145.427 1.00 126.51 ? 671 ARG   A CZ  1 
ATOM   5215 N NH1 . ARG   A 1 645 ? 176.851 120.630 145.890 1.00 125.86 ? 671 ARG   A NH1 1 
ATOM   5216 N NH2 . ARG   A 1 645 ? 175.175 119.104 146.207 1.00 124.23 ? 671 ARG   A NH2 1 
ATOM   5217 N N   . ARG   A 1 646 ? 173.233 124.011 139.933 1.00 117.89 ? 672 ARG   A N   1 
ATOM   5218 C CA  . ARG   A 1 646 ? 171.859 124.485 140.054 1.00 117.19 ? 672 ARG   A CA  1 
ATOM   5219 C C   . ARG   A 1 646 ? 171.043 124.131 138.817 1.00 116.28 ? 672 ARG   A C   1 
ATOM   5220 O O   . ARG   A 1 646 ? 169.890 123.699 138.930 1.00 111.67 ? 672 ARG   A O   1 
ATOM   5221 C CB  . ARG   A 1 646 ? 171.848 125.996 140.289 1.00 122.55 ? 672 ARG   A CB  1 
ATOM   5222 C CG  . ARG   A 1 646 ? 170.463 126.588 140.535 1.00 126.42 ? 672 ARG   A CG  1 
ATOM   5223 C CD  . ARG   A 1 646 ? 170.536 128.077 140.831 1.00 129.19 ? 672 ARG   A CD  1 
ATOM   5224 N NE  . ARG   A 1 646 ? 169.211 128.675 140.950 1.00 133.75 ? 672 ARG   A NE  1 
ATOM   5225 C CZ  . ARG   A 1 646 ? 168.973 129.964 141.160 1.00 136.11 ? 672 ARG   A CZ  1 
ATOM   5226 N NH1 . ARG   A 1 646 ? 169.957 130.843 141.284 1.00 137.94 ? 672 ARG   A NH1 1 
ATOM   5227 N NH2 . ARG   A 1 646 ? 167.715 130.384 141.247 1.00 135.07 ? 672 ARG   A NH2 1 
ATOM   5228 N N   . ARG   A 1 647 ? 171.623 124.309 137.627 1.00 119.31 ? 673 ARG   A N   1 
ATOM   5229 C CA  . ARG   A 1 647 ? 170.878 124.044 136.399 1.00 119.29 ? 673 ARG   A CA  1 
ATOM   5230 C C   . ARG   A 1 647 ? 170.485 122.575 136.289 1.00 114.26 ? 673 ARG   A C   1 
ATOM   5231 O O   . ARG   A 1 647 ? 169.349 122.256 135.920 1.00 113.98 ? 673 ARG   A O   1 
ATOM   5232 C CB  . ARG   A 1 647 ? 171.704 124.471 135.186 1.00 123.61 ? 673 ARG   A CB  1 
ATOM   5233 C CG  . ARG   A 1 647 ? 171.857 125.978 135.049 1.00 126.57 ? 673 ARG   A CG  1 
ATOM   5234 C CD  . ARG   A 1 647 ? 172.813 126.351 133.928 1.00 130.23 ? 673 ARG   A CD  1 
ATOM   5235 N NE  . ARG   A 1 647 ? 173.057 127.789 133.880 1.00 132.17 ? 673 ARG   A NE  1 
ATOM   5236 C CZ  . ARG   A 1 647 ? 173.845 128.398 133.002 1.00 131.45 ? 673 ARG   A CZ  1 
ATOM   5237 N NH1 . ARG   A 1 647 ? 174.494 127.726 132.063 1.00 128.95 ? 673 ARG   A NH1 1 
ATOM   5238 N NH2 . ARG   A 1 647 ? 173.987 129.718 133.069 1.00 130.72 ? 673 ARG   A NH2 1 
ATOM   5239 N N   . ASN   A 1 648 ? 171.407 121.668 136.607 1.00 113.44 ? 674 ASN   A N   1 
ATOM   5240 C CA  . ASN   A 1 648 ? 171.139 120.229 136.555 1.00 113.09 ? 674 ASN   A CA  1 
ATOM   5241 C C   . ASN   A 1 648 ? 170.605 119.759 137.909 1.00 109.11 ? 674 ASN   A C   1 
ATOM   5242 O O   . ASN   A 1 648 ? 171.249 119.010 138.645 1.00 111.94 ? 674 ASN   A O   1 
ATOM   5243 C CB  . ASN   A 1 648 ? 172.399 119.472 136.157 1.00 120.44 ? 674 ASN   A CB  1 
ATOM   5244 C CG  . ASN   A 1 648 ? 172.969 119.944 134.833 1.00 124.99 ? 674 ASN   A CG  1 
ATOM   5245 O OD1 . ASN   A 1 648 ? 172.231 120.362 133.941 1.00 127.01 ? 674 ASN   A OD1 1 
ATOM   5246 N ND2 . ASN   A 1 648 ? 174.289 119.880 134.700 1.00 123.53 ? 674 ASN   A ND2 1 
ATOM   5247 N N   . THR   A 1 649 ? 169.393 120.223 138.226 1.00 105.34 ? 675 THR   A N   1 
ATOM   5248 C CA  . THR   A 1 649 ? 168.736 119.945 139.500 1.00 107.41 ? 675 THR   A CA  1 
ATOM   5249 C C   . THR   A 1 649 ? 167.341 119.386 139.234 1.00 105.46 ? 675 THR   A C   1 
ATOM   5250 O O   . THR   A 1 649 ? 166.612 119.939 138.393 1.00 107.46 ? 675 THR   A O   1 
ATOM   5251 C CB  . THR   A 1 649 ? 168.648 121.219 140.348 1.00 110.82 ? 675 THR   A CB  1 
ATOM   5252 O OG1 . THR   A 1 649 ? 169.936 121.845 140.403 1.00 111.82 ? 675 THR   A OG1 1 
ATOM   5253 C CG2 . THR   A 1 649 ? 168.188 120.897 141.762 1.00 106.97 ? 675 THR   A CG2 1 
ATOM   5254 N N   . PRO   A 1 650 ? 166.918 118.311 139.908 1.00 100.11 ? 676 PRO   A N   1 
ATOM   5255 C CA  . PRO   A 1 650 ? 165.574 117.779 139.654 1.00 101.48 ? 676 PRO   A CA  1 
ATOM   5256 C C   . PRO   A 1 650 ? 164.485 118.662 140.247 1.00 104.88 ? 676 PRO   A C   1 
ATOM   5257 O O   . PRO   A 1 650 ? 164.718 119.485 141.136 1.00 107.49 ? 676 PRO   A O   1 
ATOM   5258 C CB  . PRO   A 1 650 ? 165.602 116.406 140.328 1.00 102.15 ? 676 PRO   A CB  1 
ATOM   5259 C CG  . PRO   A 1 650 ? 166.556 116.569 141.434 1.00 102.97 ? 676 PRO   A CG  1 
ATOM   5260 C CD  . PRO   A 1 650 ? 167.616 117.508 140.932 1.00 98.61  ? 676 PRO   A CD  1 
ATOM   5261 N N   . PHE   A 1 651 ? 163.267 118.471 139.732 1.00 101.51 ? 677 PHE   A N   1 
ATOM   5262 C CA  . PHE   A 1 651 ? 162.134 119.291 140.155 1.00 101.57 ? 677 PHE   A CA  1 
ATOM   5263 C C   . PHE   A 1 651 ? 161.684 118.951 141.572 1.00 99.79  ? 677 PHE   A C   1 
ATOM   5264 O O   . PHE   A 1 651 ? 161.317 119.848 142.345 1.00 101.67 ? 677 PHE   A O   1 
ATOM   5265 C CB  . PHE   A 1 651 ? 160.979 119.114 139.170 1.00 101.21 ? 677 PHE   A CB  1 
ATOM   5266 C CG  . PHE   A 1 651 ? 159.729 119.850 139.558 1.00 107.56 ? 677 PHE   A CG  1 
ATOM   5267 C CD1 . PHE   A 1 651 ? 159.608 121.209 139.324 1.00 108.15 ? 677 PHE   A CD1 1 
ATOM   5268 C CD2 . PHE   A 1 651 ? 158.670 119.180 140.148 1.00 107.30 ? 677 PHE   A CD2 1 
ATOM   5269 C CE1 . PHE   A 1 651 ? 158.457 121.888 139.677 1.00 108.06 ? 677 PHE   A CE1 1 
ATOM   5270 C CE2 . PHE   A 1 651 ? 157.517 119.853 140.503 1.00 106.10 ? 677 PHE   A CE2 1 
ATOM   5271 C CZ  . PHE   A 1 651 ? 157.411 121.209 140.267 1.00 107.74 ? 677 PHE   A CZ  1 
ATOM   5272 N N   . HIS   A 1 652 ? 161.691 117.663 141.925 1.00 92.98  ? 678 HIS   A N   1 
ATOM   5273 C CA  . HIS   A 1 652 ? 161.163 117.247 143.222 1.00 92.83  ? 678 HIS   A CA  1 
ATOM   5274 C C   . HIS   A 1 652 ? 161.960 117.851 144.373 1.00 96.91  ? 678 HIS   A C   1 
ATOM   5275 O O   . HIS   A 1 652 ? 161.388 118.208 145.412 1.00 99.42  ? 678 HIS   A O   1 
ATOM   5276 C CB  . HIS   A 1 652 ? 161.132 115.718 143.327 1.00 89.58  ? 678 HIS   A CB  1 
ATOM   5277 C CG  . HIS   A 1 652 ? 162.434 115.050 143.012 1.00 89.68  ? 678 HIS   A CG  1 
ATOM   5278 N ND1 . HIS   A 1 652 ? 163.497 115.031 143.887 1.00 91.15  ? 678 HIS   A ND1 1 
ATOM   5279 C CD2 . HIS   A 1 652 ? 162.840 114.371 141.913 1.00 93.98  ? 678 HIS   A CD2 1 
ATOM   5280 C CE1 . HIS   A 1 652 ? 164.503 114.371 143.341 1.00 95.56  ? 678 HIS   A CE1 1 
ATOM   5281 N NE2 . HIS   A 1 652 ? 164.131 113.962 142.143 1.00 97.99  ? 678 HIS   A NE2 1 
ATOM   5282 N N   . GLU   A 1 653 ? 163.280 117.975 144.211 1.00 95.95  ? 679 GLU   A N   1 
ATOM   5283 C CA  . GLU   A 1 653 ? 164.081 118.633 145.237 1.00 99.42  ? 679 GLU   A CA  1 
ATOM   5284 C C   . GLU   A 1 653 ? 163.648 120.080 145.420 1.00 98.72  ? 679 GLU   A C   1 
ATOM   5285 O O   . GLU   A 1 653 ? 163.547 120.569 146.552 1.00 98.71  ? 679 GLU   A O   1 
ATOM   5286 C CB  . GLU   A 1 653 ? 165.565 118.566 144.876 1.00 103.76 ? 679 GLU   A CB  1 
ATOM   5287 C CG  . GLU   A 1 653 ? 166.214 117.220 145.148 1.00 105.95 ? 679 GLU   A CG  1 
ATOM   5288 C CD  . GLU   A 1 653 ? 167.693 117.209 144.812 1.00 113.21 ? 679 GLU   A CD  1 
ATOM   5289 O OE1 . GLU   A 1 653 ? 168.227 118.273 144.434 1.00 115.06 ? 679 GLU   A OE1 1 
ATOM   5290 O OE2 . GLU   A 1 653 ? 168.321 116.135 144.926 1.00 112.06 ? 679 GLU   A OE2 1 
ATOM   5291 N N   . ARG   A 1 654 ? 163.382 120.781 144.316 1.00 95.84  ? 680 ARG   A N   1 
ATOM   5292 C CA  . ARG   A 1 654 ? 162.934 122.165 144.415 1.00 96.85  ? 680 ARG   A CA  1 
ATOM   5293 C C   . ARG   A 1 654 ? 161.588 122.255 145.119 1.00 90.28  ? 680 ARG   A C   1 
ATOM   5294 O O   . ARG   A 1 654 ? 161.368 123.152 145.942 1.00 90.24  ? 680 ARG   A O   1 
ATOM   5295 C CB  . ARG   A 1 654 ? 162.855 122.793 143.023 1.00 103.69 ? 680 ARG   A CB  1 
ATOM   5296 C CG  . ARG   A 1 654 ? 164.201 122.921 142.330 1.00 106.42 ? 680 ARG   A CG  1 
ATOM   5297 C CD  . ARG   A 1 654 ? 164.076 123.475 140.914 1.00 109.59 ? 680 ARG   A CD  1 
ATOM   5298 N NE  . ARG   A 1 654 ? 163.607 124.858 140.884 1.00 116.02 ? 680 ARG   A NE  1 
ATOM   5299 C CZ  . ARG   A 1 654 ? 162.339 125.246 140.799 1.00 114.28 ? 680 ARG   A CZ  1 
ATOM   5300 N NH1 . ARG   A 1 654 ? 161.341 124.375 140.752 1.00 111.52 ? 680 ARG   A NH1 1 
ATOM   5301 N NH2 . ARG   A 1 654 ? 162.062 126.546 140.763 1.00 112.03 ? 680 ARG   A NH2 1 
ATOM   5302 N N   . PHE   A 1 655 ? 160.674 121.335 144.808 1.00 85.60  ? 681 PHE   A N   1 
ATOM   5303 C CA  . PHE   A 1 655 ? 159.370 121.352 145.462 1.00 86.92  ? 681 PHE   A CA  1 
ATOM   5304 C C   . PHE   A 1 655 ? 159.504 121.116 146.962 1.00 88.77  ? 681 PHE   A C   1 
ATOM   5305 O O   . PHE   A 1 655 ? 158.868 121.808 147.773 1.00 92.92  ? 681 PHE   A O   1 
ATOM   5306 C CB  . PHE   A 1 655 ? 158.459 120.302 144.830 1.00 87.03  ? 681 PHE   A CB  1 
ATOM   5307 C CG  . PHE   A 1 655 ? 157.043 120.356 145.317 1.00 86.25  ? 681 PHE   A CG  1 
ATOM   5308 C CD1 . PHE   A 1 655 ? 156.136 121.232 144.752 1.00 84.48  ? 681 PHE   A CD1 1 
ATOM   5309 C CD2 . PHE   A 1 655 ? 156.616 119.526 146.337 1.00 85.79  ? 681 PHE   A CD2 1 
ATOM   5310 C CE1 . PHE   A 1 655 ? 154.834 121.282 145.196 1.00 83.44  ? 681 PHE   A CE1 1 
ATOM   5311 C CE2 . PHE   A 1 655 ? 155.314 119.573 146.785 1.00 84.56  ? 681 PHE   A CE2 1 
ATOM   5312 C CZ  . PHE   A 1 655 ? 154.423 120.451 146.213 1.00 83.83  ? 681 PHE   A CZ  1 
ATOM   5313 N N   . PHE   A 1 656 ? 160.345 120.156 147.352 1.00 84.78  ? 682 PHE   A N   1 
ATOM   5314 C CA  . PHE   A 1 656 ? 160.540 119.884 148.772 1.00 84.59  ? 682 PHE   A CA  1 
ATOM   5315 C C   . PHE   A 1 656 ? 161.172 121.078 149.479 1.00 85.55  ? 682 PHE   A C   1 
ATOM   5316 O O   . PHE   A 1 656 ? 160.785 121.422 150.604 1.00 85.72  ? 682 PHE   A O   1 
ATOM   5317 C CB  . PHE   A 1 656 ? 161.398 118.633 148.946 1.00 85.68  ? 682 PHE   A CB  1 
ATOM   5318 C CG  . PHE   A 1 656 ? 161.377 118.073 150.337 1.00 89.07  ? 682 PHE   A CG  1 
ATOM   5319 C CD1 . PHE   A 1 656 ? 160.293 117.340 150.785 1.00 89.07  ? 682 PHE   A CD1 1 
ATOM   5320 C CD2 . PHE   A 1 656 ? 162.444 118.273 151.195 1.00 91.37  ? 682 PHE   A CD2 1 
ATOM   5321 C CE1 . PHE   A 1 656 ? 160.271 116.822 152.064 1.00 91.40  ? 682 PHE   A CE1 1 
ATOM   5322 C CE2 . PHE   A 1 656 ? 162.428 117.757 152.475 1.00 91.80  ? 682 PHE   A CE2 1 
ATOM   5323 C CZ  . PHE   A 1 656 ? 161.339 117.030 152.909 1.00 91.40  ? 682 PHE   A CZ  1 
ATOM   5324 N N   . ARG   A 1 657 ? 162.144 121.727 148.833 1.00 84.30  ? 683 ARG   A N   1 
ATOM   5325 C CA  . ARG   A 1 657 ? 162.762 122.909 149.424 1.00 84.58  ? 683 ARG   A CA  1 
ATOM   5326 C C   . ARG   A 1 657 ? 161.748 124.033 149.593 1.00 82.79  ? 683 ARG   A C   1 
ATOM   5327 O O   . ARG   A 1 657 ? 161.760 124.744 150.606 1.00 86.53  ? 683 ARG   A O   1 
ATOM   5328 C CB  . ARG   A 1 657 ? 163.938 123.372 148.565 1.00 92.01  ? 683 ARG   A CB  1 
ATOM   5329 C CG  . ARG   A 1 657 ? 165.163 122.473 148.654 1.00 98.89  ? 683 ARG   A CG  1 
ATOM   5330 C CD  . ARG   A 1 657 ? 166.268 122.946 147.723 1.00 103.01 ? 683 ARG   A CD  1 
ATOM   5331 N NE  . ARG   A 1 657 ? 167.417 122.047 147.726 1.00 109.62 ? 683 ARG   A NE  1 
ATOM   5332 C CZ  . ARG   A 1 657 ? 168.526 122.230 147.021 1.00 110.54 ? 683 ARG   A CZ  1 
ATOM   5333 N NH1 . ARG   A 1 657 ? 168.687 123.283 146.234 1.00 109.63 ? 683 ARG   A NH1 1 
ATOM   5334 N NH2 . ARG   A 1 657 ? 169.503 121.331 147.107 1.00 109.33 ? 683 ARG   A NH2 1 
ATOM   5335 N N   . PHE   A 1 658 ? 160.871 124.216 148.604 1.00 77.50  ? 684 PHE   A N   1 
ATOM   5336 C CA  . PHE   A 1 658 ? 159.833 125.236 148.710 1.00 76.87  ? 684 PHE   A CA  1 
ATOM   5337 C C   . PHE   A 1 658 ? 158.920 124.965 149.899 1.00 77.64  ? 684 PHE   A C   1 
ATOM   5338 O O   . PHE   A 1 658 ? 158.597 125.881 150.675 1.00 79.78  ? 684 PHE   A O   1 
ATOM   5339 C CB  . PHE   A 1 658 ? 159.032 125.275 147.408 1.00 74.09  ? 684 PHE   A CB  1 
ATOM   5340 C CG  . PHE   A 1 658 ? 157.909 126.270 147.406 1.00 72.21  ? 684 PHE   A CG  1 
ATOM   5341 C CD1 . PHE   A 1 658 ? 158.133 127.580 147.030 1.00 75.91  ? 684 PHE   A CD1 1 
ATOM   5342 C CD2 . PHE   A 1 658 ? 156.627 125.889 147.753 1.00 73.57  ? 684 PHE   A CD2 1 
ATOM   5343 C CE1 . PHE   A 1 658 ? 157.103 128.494 147.018 1.00 77.11  ? 684 PHE   A CE1 1 
ATOM   5344 C CE2 . PHE   A 1 658 ? 155.595 126.798 147.744 1.00 75.40  ? 684 PHE   A CE2 1 
ATOM   5345 C CZ  . PHE   A 1 658 ? 155.832 128.102 147.374 1.00 76.66  ? 684 PHE   A CZ  1 
ATOM   5346 N N   . LEU   A 1 659 ? 158.496 123.708 150.057 1.00 77.00  ? 685 LEU   A N   1 
ATOM   5347 C CA  . LEU   A 1 659 ? 157.640 123.364 151.188 1.00 77.00  ? 685 LEU   A CA  1 
ATOM   5348 C C   . LEU   A 1 659 ? 158.347 123.623 152.511 1.00 73.80  ? 685 LEU   A C   1 
ATOM   5349 O O   . LEU   A 1 659 ? 157.746 124.163 153.449 1.00 75.58  ? 685 LEU   A O   1 
ATOM   5350 C CB  . LEU   A 1 659 ? 157.194 121.903 151.095 1.00 79.34  ? 685 LEU   A CB  1 
ATOM   5351 C CG  . LEU   A 1 659 ? 155.845 121.609 150.427 1.00 81.35  ? 685 LEU   A CG  1 
ATOM   5352 C CD1 . LEU   A 1 659 ? 154.689 122.190 151.230 1.00 79.93  ? 685 LEU   A CD1 1 
ATOM   5353 C CD2 . LEU   A 1 659 ? 155.802 122.117 148.993 1.00 81.87  ? 685 LEU   A CD2 1 
ATOM   5354 N N   . LEU   A 1 660 ? 159.626 123.253 152.604 1.00 72.02  ? 686 LEU   A N   1 
ATOM   5355 C CA  . LEU   A 1 660 ? 160.364 123.483 153.843 1.00 72.01  ? 686 LEU   A CA  1 
ATOM   5356 C C   . LEU   A 1 660 ? 160.483 124.971 154.151 1.00 69.72  ? 686 LEU   A C   1 
ATOM   5357 O O   . LEU   A 1 660 ? 160.363 125.384 155.311 1.00 73.30  ? 686 LEU   A O   1 
ATOM   5358 C CB  . LEU   A 1 660 ? 161.749 122.843 153.768 1.00 76.70  ? 686 LEU   A CB  1 
ATOM   5359 C CG  . LEU   A 1 660 ? 161.878 121.495 154.479 1.00 80.86  ? 686 LEU   A CG  1 
ATOM   5360 C CD1 . LEU   A 1 660 ? 160.926 120.464 153.892 1.00 82.43  ? 686 LEU   A CD1 1 
ATOM   5361 C CD2 . LEU   A 1 660 ? 163.314 120.996 154.415 1.00 82.56  ? 686 LEU   A CD2 1 
ATOM   5362 N N   . ARG   A 1 661 ? 160.727 125.791 153.129 1.00 66.63  ? 687 ARG   A N   1 
ATOM   5363 C CA  . ARG   A 1 661 ? 160.865 127.225 153.360 1.00 71.51  ? 687 ARG   A CA  1 
ATOM   5364 C C   . ARG   A 1 661 ? 159.560 127.837 153.859 1.00 72.33  ? 687 ARG   A C   1 
ATOM   5365 O O   . ARG   A 1 661 ? 159.559 128.651 154.797 1.00 74.75  ? 687 ARG   A O   1 
ATOM   5366 C CB  . ARG   A 1 661 ? 161.333 127.910 152.079 1.00 74.13  ? 687 ARG   A CB  1 
ATOM   5367 C CG  . ARG   A 1 661 ? 161.368 129.421 152.164 1.00 78.83  ? 687 ARG   A CG  1 
ATOM   5368 C CD  . ARG   A 1 661 ? 162.296 130.033 151.124 1.00 83.88  ? 687 ARG   A CD  1 
ATOM   5369 N NE  . ARG   A 1 661 ? 162.087 129.488 149.784 1.00 85.99  ? 687 ARG   A NE  1 
ATOM   5370 C CZ  . ARG   A 1 661 ? 162.815 128.539 149.205 1.00 87.80  ? 687 ARG   A CZ  1 
ATOM   5371 N NH1 . ARG   A 1 661 ? 163.834 127.958 149.822 1.00 84.11  ? 687 ARG   A NH1 1 
ATOM   5372 N NH2 . ARG   A 1 661 ? 162.513 128.160 147.966 1.00 88.19  ? 687 ARG   A NH2 1 
ATOM   5373 N N   . LYS   A 1 662 ? 158.434 127.454 153.254 1.00 68.36  ? 688 LYS   A N   1 
ATOM   5374 C CA  . LYS   A 1 662 ? 157.156 127.977 153.732 1.00 64.04  ? 688 LYS   A CA  1 
ATOM   5375 C C   . LYS   A 1 662 ? 156.860 127.492 155.148 1.00 62.46  ? 688 LYS   A C   1 
ATOM   5376 O O   . LYS   A 1 662 ? 156.317 128.244 155.974 1.00 65.60  ? 688 LYS   A O   1 
ATOM   5377 C CB  . LYS   A 1 662 ? 156.037 127.585 152.771 1.00 66.38  ? 688 LYS   A CB  1 
ATOM   5378 C CG  . LYS   A 1 662 ? 156.180 128.177 151.373 1.00 69.01  ? 688 LYS   A CG  1 
ATOM   5379 C CD  . LYS   A 1 662 ? 156.028 129.693 151.367 1.00 70.32  ? 688 LYS   A CD  1 
ATOM   5380 C CE  . LYS   A 1 662 ? 156.101 130.255 149.962 1.00 73.20  ? 688 LYS   A CE  1 
ATOM   5381 N NZ  . LYS   A 1 662 ? 156.184 131.740 149.962 1.00 73.03  ? 688 LYS   A NZ  1 
ATOM   5382 N N   . LEU   A 1 663 ? 157.220 126.242 155.451 1.00 61.45  ? 689 LEU   A N   1 
ATOM   5383 C CA  . LEU   A 1 663 ? 157.072 125.742 156.813 1.00 60.88  ? 689 LEU   A CA  1 
ATOM   5384 C C   . LEU   A 1 663 ? 157.877 126.587 157.789 1.00 63.69  ? 689 LEU   A C   1 
ATOM   5385 O O   . LEU   A 1 663 ? 157.405 126.901 158.888 1.00 64.54  ? 689 LEU   A O   1 
ATOM   5386 C CB  . LEU   A 1 663 ? 157.509 124.279 156.878 1.00 64.74  ? 689 LEU   A CB  1 
ATOM   5387 C CG  . LEU   A 1 663 ? 157.446 123.563 158.229 1.00 65.61  ? 689 LEU   A CG  1 
ATOM   5388 C CD1 . LEU   A 1 663 ? 156.023 123.510 158.753 1.00 66.66  ? 689 LEU   A CD1 1 
ATOM   5389 C CD2 . LEU   A 1 663 ? 158.019 122.164 158.107 1.00 63.34  ? 689 LEU   A CD2 1 
ATOM   5390 N N   . TYR   A 1 664 ? 159.095 126.969 157.398 1.00 66.68  ? 690 TYR   A N   1 
ATOM   5391 C CA  . TYR   A 1 664 ? 159.920 127.814 158.257 1.00 65.56  ? 690 TYR   A CA  1 
ATOM   5392 C C   . TYR   A 1 664 ? 159.258 129.161 158.501 1.00 61.78  ? 690 TYR   A C   1 
ATOM   5393 O O   . TYR   A 1 664 ? 159.267 129.670 159.629 1.00 63.63  ? 690 TYR   A O   1 
ATOM   5394 C CB  . TYR   A 1 664 ? 161.300 128.014 157.636 1.00 72.07  ? 690 TYR   A CB  1 
ATOM   5395 C CG  . TYR   A 1 664 ? 162.071 129.159 158.254 1.00 79.84  ? 690 TYR   A CG  1 
ATOM   5396 C CD1 . TYR   A 1 664 ? 162.574 129.068 159.545 1.00 78.21  ? 690 TYR   A CD1 1 
ATOM   5397 C CD2 . TYR   A 1 664 ? 162.294 130.334 157.548 1.00 81.12  ? 690 TYR   A CD2 1 
ATOM   5398 C CE1 . TYR   A 1 664 ? 163.277 130.113 160.115 1.00 77.04  ? 690 TYR   A CE1 1 
ATOM   5399 C CE2 . TYR   A 1 664 ? 162.996 131.384 158.109 1.00 83.30  ? 690 TYR   A CE2 1 
ATOM   5400 C CZ  . TYR   A 1 664 ? 163.485 131.267 159.392 1.00 81.04  ? 690 TYR   A CZ  1 
ATOM   5401 O OH  . TYR   A 1 664 ? 164.185 132.309 159.956 1.00 76.62  ? 690 TYR   A OH  1 
ATOM   5402 N N   . VAL   A 1 665 ? 158.684 129.755 157.452 1.00 60.28  ? 691 VAL   A N   1 
ATOM   5403 C CA  . VAL   A 1 665 ? 158.031 131.056 157.603 1.00 58.31  ? 691 VAL   A CA  1 
ATOM   5404 C C   . VAL   A 1 665 ? 156.884 130.963 158.605 1.00 57.39  ? 691 VAL   A C   1 
ATOM   5405 O O   . VAL   A 1 665 ? 156.779 131.775 159.539 1.00 59.94  ? 691 VAL   A O   1 
ATOM   5406 C CB  . VAL   A 1 665 ? 157.546 131.576 156.237 1.00 56.44  ? 691 VAL   A CB  1 
ATOM   5407 C CG1 . VAL   A 1 665 ? 156.673 132.805 156.405 1.00 54.19  ? 691 VAL   A CG1 1 
ATOM   5408 C CG2 . VAL   A 1 665 ? 158.730 131.895 155.338 1.00 62.81  ? 691 VAL   A CG2 1 
ATOM   5409 N N   . PHE   A 1 666 ? 156.018 129.960 158.439 1.00 55.38  ? 692 PHE   A N   1 
ATOM   5410 C CA  . PHE   A 1 666 ? 154.872 129.833 159.339 1.00 50.92  ? 692 PHE   A CA  1 
ATOM   5411 C C   . PHE   A 1 666 ? 155.315 129.543 160.770 1.00 54.21  ? 692 PHE   A C   1 
ATOM   5412 O O   . PHE   A 1 666 ? 154.755 130.097 161.730 1.00 56.94  ? 692 PHE   A O   1 
ATOM   5413 C CB  . PHE   A 1 666 ? 153.924 128.745 158.839 1.00 52.85  ? 692 PHE   A CB  1 
ATOM   5414 C CG  . PHE   A 1 666 ? 153.037 129.187 157.710 1.00 58.48  ? 692 PHE   A CG  1 
ATOM   5415 C CD1 . PHE   A 1 666 ? 151.924 129.965 157.951 1.00 56.94  ? 692 PHE   A CD1 1 
ATOM   5416 C CD2 . PHE   A 1 666 ? 153.312 128.817 156.409 1.00 60.71  ? 692 PHE   A CD2 1 
ATOM   5417 C CE1 . PHE   A 1 666 ? 151.109 130.365 156.915 1.00 54.89  ? 692 PHE   A CE1 1 
ATOM   5418 C CE2 . PHE   A 1 666 ? 152.500 129.218 155.373 1.00 57.39  ? 692 PHE   A CE2 1 
ATOM   5419 C CZ  . PHE   A 1 666 ? 151.399 129.993 155.627 1.00 56.36  ? 692 PHE   A CZ  1 
ATOM   5420 N N   . ARG   A 1 667 ? 156.322 128.681 160.934 1.00 52.54  ? 693 ARG   A N   1 
ATOM   5421 C CA  . ARG   A 1 667 ? 156.825 128.365 162.266 1.00 49.53  ? 693 ARG   A CA  1 
ATOM   5422 C C   . ARG   A 1 667 ? 157.369 129.607 162.961 1.00 53.03  ? 693 ARG   A C   1 
ATOM   5423 O O   . ARG   A 1 667 ? 157.077 129.849 164.141 1.00 52.18  ? 693 ARG   A O   1 
ATOM   5424 C CB  . ARG   A 1 667 ? 157.905 127.289 162.151 1.00 44.20  ? 693 ARG   A CB  1 
ATOM   5425 C CG  . ARG   A 1 667 ? 158.583 126.896 163.450 1.00 41.15  ? 693 ARG   A CG  1 
ATOM   5426 C CD  . ARG   A 1 667 ? 159.537 125.755 163.215 1.00 41.13  ? 693 ARG   A CD  1 
ATOM   5427 N NE  . ARG   A 1 667 ? 160.658 125.764 164.147 1.00 39.17  ? 693 ARG   A NE  1 
ATOM   5428 C CZ  . ARG   A 1 667 ? 160.708 125.118 165.304 1.00 45.95  ? 693 ARG   A CZ  1 
ATOM   5429 N NH1 . ARG   A 1 667 ? 159.685 124.408 165.755 1.00 49.19  ? 693 ARG   A NH1 1 
ATOM   5430 N NH2 . ARG   A 1 667 ? 161.817 125.184 166.032 1.00 53.16  ? 693 ARG   A NH2 1 
ATOM   5431 N N   . ARG   A 1 668 ? 158.160 130.408 162.242 1.00 55.33  ? 694 ARG   A N   1 
ATOM   5432 C CA  . ARG   A 1 668 ? 158.724 131.612 162.840 1.00 50.21  ? 694 ARG   A CA  1 
ATOM   5433 C C   . ARG   A 1 668 ? 157.625 132.577 163.248 1.00 50.37  ? 694 ARG   A C   1 
ATOM   5434 O O   . ARG   A 1 668 ? 157.668 133.150 164.345 1.00 54.83  ? 694 ARG   A O   1 
ATOM   5435 C CB  . ARG   A 1 668 ? 159.683 132.277 161.858 1.00 58.34  ? 694 ARG   A CB  1 
ATOM   5436 C CG  . ARG   A 1 668 ? 160.566 133.346 162.471 1.00 64.43  ? 694 ARG   A CG  1 
ATOM   5437 C CD  . ARG   A 1 668 ? 161.480 133.960 161.424 1.00 67.61  ? 694 ARG   A CD  1 
ATOM   5438 N NE  . ARG   A 1 668 ? 162.473 134.848 162.016 1.00 66.95  ? 694 ARG   A NE  1 
ATOM   5439 C CZ  . ARG   A 1 668 ? 162.248 136.100 162.395 1.00 67.74  ? 694 ARG   A CZ  1 
ATOM   5440 N NH1 . ARG   A 1 668 ? 161.057 136.665 162.269 1.00 65.65  ? 694 ARG   A NH1 1 
ATOM   5441 N NH2 . ARG   A 1 668 ? 163.247 136.805 162.918 1.00 70.44  ? 694 ARG   A NH2 1 
ATOM   5442 N N   . SER   A 1 669 ? 156.618 132.751 162.385 1.00 50.86  ? 695 SER   A N   1 
ATOM   5443 C CA  . SER   A 1 669 ? 155.514 133.648 162.714 1.00 50.45  ? 695 SER   A CA  1 
ATOM   5444 C C   . SER   A 1 669 ? 154.819 133.212 163.997 1.00 49.56  ? 695 SER   A C   1 
ATOM   5445 O O   . SER   A 1 669 ? 154.617 134.019 164.917 1.00 53.16  ? 695 SER   A O   1 
ATOM   5446 C CB  . SER   A 1 669 ? 154.518 133.694 161.557 1.00 47.40  ? 695 SER   A CB  1 
ATOM   5447 O OG  . SER   A 1 669 ? 155.141 134.136 160.367 1.00 51.94  ? 695 SER   A OG  1 
ATOM   5448 N N   . PHE   A 1 670 ? 154.475 131.925 164.087 1.00 45.65  ? 696 PHE   A N   1 
ATOM   5449 C CA  . PHE   A 1 670 ? 153.741 131.440 165.251 1.00 46.76  ? 696 PHE   A CA  1 
ATOM   5450 C C   . PHE   A 1 670 ? 154.560 131.591 166.528 1.00 52.28  ? 696 PHE   A C   1 
ATOM   5451 O O   . PHE   A 1 670 ? 154.057 132.082 167.549 1.00 54.90  ? 696 PHE   A O   1 
ATOM   5452 C CB  . PHE   A 1 670 ? 153.332 129.983 165.038 1.00 47.49  ? 696 PHE   A CB  1 
ATOM   5453 C CG  . PHE   A 1 670 ? 152.654 129.363 166.225 1.00 48.11  ? 696 PHE   A CG  1 
ATOM   5454 C CD1 . PHE   A 1 670 ? 151.531 129.946 166.779 1.00 52.30  ? 696 PHE   A CD1 1 
ATOM   5455 C CD2 . PHE   A 1 670 ? 153.135 128.193 166.777 1.00 47.92  ? 696 PHE   A CD2 1 
ATOM   5456 C CE1 . PHE   A 1 670 ? 150.907 129.378 167.868 1.00 55.81  ? 696 PHE   A CE1 1 
ATOM   5457 C CE2 . PHE   A 1 670 ? 152.513 127.621 167.865 1.00 51.94  ? 696 PHE   A CE2 1 
ATOM   5458 C CZ  . PHE   A 1 670 ? 151.398 128.214 168.412 1.00 54.73  ? 696 PHE   A CZ  1 
ATOM   5459 N N   . LEU   A 1 671 ? 155.833 131.182 166.491 1.00 49.92  ? 697 LEU   A N   1 
ATOM   5460 C CA  . LEU   A 1 671 ? 156.645 131.231 167.704 1.00 45.13  ? 697 LEU   A CA  1 
ATOM   5461 C C   . LEU   A 1 671 ? 156.868 132.667 168.172 1.00 48.33  ? 697 LEU   A C   1 
ATOM   5462 O O   . LEU   A 1 671 ? 156.788 132.955 169.376 1.00 48.70  ? 697 LEU   A O   1 
ATOM   5463 C CB  . LEU   A 1 671 ? 157.978 130.521 167.473 1.00 45.14  ? 697 LEU   A CB  1 
ATOM   5464 C CG  . LEU   A 1 671 ? 158.055 129.016 167.768 1.00 47.01  ? 697 LEU   A CG  1 
ATOM   5465 C CD1 . LEU   A 1 671 ? 157.874 128.731 169.254 1.00 50.28  ? 697 LEU   A CD1 1 
ATOM   5466 C CD2 . LEU   A 1 671 ? 157.054 128.211 166.954 1.00 48.34  ? 697 LEU   A CD2 1 
ATOM   5467 N N   . MET   A 1 672 ? 157.152 133.586 167.244 1.00 51.03  ? 698 MET   A N   1 
ATOM   5468 C CA  . MET   A 1 672 ? 157.366 134.972 167.646 1.00 48.77  ? 698 MET   A CA  1 
ATOM   5469 C C   . MET   A 1 672 ? 156.091 135.587 168.213 1.00 47.39  ? 698 MET   A C   1 
ATOM   5470 O O   . MET   A 1 672 ? 156.143 136.355 169.185 1.00 47.68  ? 698 MET   A O   1 
ATOM   5471 C CB  . MET   A 1 672 ? 157.884 135.786 166.461 1.00 49.98  ? 698 MET   A CB  1 
ATOM   5472 C CG  . MET   A 1 672 ? 159.261 135.358 165.970 1.00 53.25  ? 698 MET   A CG  1 
ATOM   5473 S SD  . MET   A 1 672 ? 160.598 135.652 167.141 1.00 60.58  ? 698 MET   A SD  1 
ATOM   5474 C CE  . MET   A 1 672 ? 160.792 137.425 167.016 1.00 58.16  ? 698 MET   A CE  1 
ATOM   5475 N N   . THR   A 1 673 ? 154.934 135.272 167.621 1.00 47.05  ? 699 THR   A N   1 
ATOM   5476 C CA  . THR   A 1 673 ? 153.679 135.771 168.177 1.00 45.83  ? 699 THR   A CA  1 
ATOM   5477 C C   . THR   A 1 673 ? 153.462 135.244 169.588 1.00 49.00  ? 699 THR   A C   1 
ATOM   5478 O O   . THR   A 1 673 ? 152.986 135.975 170.468 1.00 49.20  ? 699 THR   A O   1 
ATOM   5479 C CB  . THR   A 1 673 ? 152.508 135.382 167.275 1.00 51.09  ? 699 THR   A CB  1 
ATOM   5480 O OG1 . THR   A 1 673 ? 152.650 136.021 166.001 1.00 52.15  ? 699 THR   A OG1 1 
ATOM   5481 C CG2 . THR   A 1 673 ? 151.187 135.801 167.899 1.00 49.99  ? 699 THR   A CG2 1 
ATOM   5482 N N   . CYS   A 1 674 ? 153.808 133.974 169.823 1.00 53.29  ? 700 CYS   A N   1 
ATOM   5483 C CA  . CYS   A 1 674 ? 153.700 133.418 171.169 1.00 50.84  ? 700 CYS   A CA  1 
ATOM   5484 C C   . CYS   A 1 674 ? 154.583 134.179 172.151 1.00 49.71  ? 700 CYS   A C   1 
ATOM   5485 O O   . CYS   A 1 674 ? 154.151 134.497 173.267 1.00 47.29  ? 700 CYS   A O   1 
ATOM   5486 C CB  . CYS   A 1 674 ? 154.070 131.936 171.157 1.00 46.51  ? 700 CYS   A CB  1 
ATOM   5487 S SG  . CYS   A 1 674 ? 152.816 130.855 170.441 1.00 58.90  ? 700 CYS   A SG  1 
ATOM   5488 N N   . ILE   A 1 675 ? 155.822 134.477 171.751 1.00 51.72  ? 701 ILE   A N   1 
ATOM   5489 C CA  . ILE   A 1 675 ? 156.736 135.206 172.632 1.00 41.83  ? 701 ILE   A CA  1 
ATOM   5490 C C   . ILE   A 1 675 ? 156.155 136.570 172.975 1.00 44.06  ? 701 ILE   A C   1 
ATOM   5491 O O   . ILE   A 1 675 ? 156.166 137.000 174.136 1.00 50.00  ? 701 ILE   A O   1 
ATOM   5492 C CB  . ILE   A 1 675 ? 158.127 135.340 171.984 1.00 42.37  ? 701 ILE   A CB  1 
ATOM   5493 C CG1 . ILE   A 1 675 ? 158.793 133.968 171.837 1.00 49.51  ? 701 ILE   A CG1 1 
ATOM   5494 C CG2 . ILE   A 1 675 ? 159.009 136.261 172.813 1.00 45.76  ? 701 ILE   A CG2 1 
ATOM   5495 C CD1 . ILE   A 1 675 ? 159.960 133.942 170.866 1.00 51.63  ? 701 ILE   A CD1 1 
ATOM   5496 N N   . SER   A 1 676 ? 155.632 137.269 171.966 1.00 49.77  ? 702 SER   A N   1 
ATOM   5497 C CA  . SER   A 1 676 ? 155.074 138.598 172.201 1.00 51.65  ? 702 SER   A CA  1 
ATOM   5498 C C   . SER   A 1 676 ? 153.882 138.546 173.149 1.00 51.82  ? 702 SER   A C   1 
ATOM   5499 O O   . SER   A 1 676 ? 153.772 139.368 174.066 1.00 49.73  ? 702 SER   A O   1 
ATOM   5500 C CB  . SER   A 1 676 ? 154.664 139.235 170.876 1.00 55.52  ? 702 SER   A CB  1 
ATOM   5501 O OG  . SER   A 1 676 ? 153.710 140.259 171.088 1.00 56.39  ? 702 SER   A OG  1 
ATOM   5502 N N   . LEU   A 1 677 ? 152.973 137.591 172.938 1.00 54.37  ? 703 LEU   A N   1 
ATOM   5503 C CA  . LEU   A 1 677 ? 151.793 137.502 173.793 1.00 52.70  ? 703 LEU   A CA  1 
ATOM   5504 C C   . LEU   A 1 677 ? 152.178 137.163 175.227 1.00 50.33  ? 703 LEU   A C   1 
ATOM   5505 O O   . LEU   A 1 677 ? 151.607 137.713 176.180 1.00 51.55  ? 703 LEU   A O   1 
ATOM   5506 C CB  . LEU   A 1 677 ? 150.820 136.465 173.230 1.00 51.50  ? 703 LEU   A CB  1 
ATOM   5507 C CG  . LEU   A 1 677 ? 150.190 136.827 171.883 1.00 49.86  ? 703 LEU   A CG  1 
ATOM   5508 C CD1 . LEU   A 1 677 ? 149.548 135.611 171.247 1.00 49.57  ? 703 LEU   A CD1 1 
ATOM   5509 C CD2 . LEU   A 1 677 ? 149.167 137.935 172.047 1.00 46.75  ? 703 LEU   A CD2 1 
ATOM   5510 N N   . ARG   A 1 678 ? 153.142 136.256 175.403 1.00 51.10  ? 704 ARG   A N   1 
ATOM   5511 C CA  . ARG   A 1 678 ? 153.616 135.941 176.744 1.00 50.29  ? 704 ARG   A CA  1 
ATOM   5512 C C   . ARG   A 1 678 ? 154.200 137.178 177.413 1.00 50.73  ? 704 ARG   A C   1 
ATOM   5513 O O   . ARG   A 1 678 ? 153.939 137.435 178.594 1.00 51.94  ? 704 ARG   A O   1 
ATOM   5514 C CB  . ARG   A 1 678 ? 154.654 134.821 176.677 1.00 49.00  ? 704 ARG   A CB  1 
ATOM   5515 C CG  . ARG   A 1 678 ? 155.175 134.322 178.034 1.00 50.65  ? 704 ARG   A CG  1 
ATOM   5516 C CD  . ARG   A 1 678 ? 156.611 133.833 177.950 1.00 48.69  ? 704 ARG   A CD  1 
ATOM   5517 N NE  . ARG   A 1 678 ? 157.533 134.892 177.558 1.00 47.35  ? 704 ARG   A NE  1 
ATOM   5518 C CZ  . ARG   A 1 678 ? 158.846 134.754 177.448 1.00 54.16  ? 704 ARG   A CZ  1 
ATOM   5519 N NH1 . ARG   A 1 678 ? 159.453 133.615 177.740 1.00 58.34  ? 704 ARG   A NH1 1 
ATOM   5520 N NH2 . ARG   A 1 678 ? 159.572 135.787 177.032 1.00 59.30  ? 704 ARG   A NH2 1 
ATOM   5521 N N   . ASN   A 1 679 ? 154.992 137.956 176.673 1.00 53.43  ? 705 ASN   A N   1 
ATOM   5522 C CA  . ASN   A 1 679 ? 155.553 139.176 177.242 1.00 53.14  ? 705 ASN   A CA  1 
ATOM   5523 C C   . ASN   A 1 679 ? 154.452 140.142 177.655 1.00 54.30  ? 705 ASN   A C   1 
ATOM   5524 O O   . ASN   A 1 679 ? 154.536 140.775 178.714 1.00 54.09  ? 705 ASN   A O   1 
ATOM   5525 C CB  . ASN   A 1 679 ? 156.495 139.837 176.239 1.00 55.96  ? 705 ASN   A CB  1 
ATOM   5526 C CG  . ASN   A 1 679 ? 157.700 138.984 175.926 1.00 58.74  ? 705 ASN   A CG  1 
ATOM   5527 O OD1 . ASN   A 1 679 ? 157.731 137.795 176.242 1.00 61.60  ? 705 ASN   A OD1 1 
ATOM   5528 N ND2 . ASN   A 1 679 ? 158.701 139.583 175.297 1.00 60.38  ? 705 ASN   A ND2 1 
ATOM   5529 N N   . LEU   A 1 680 ? 153.413 140.274 176.828 1.00 57.47  ? 706 LEU   A N   1 
ATOM   5530 C CA  . LEU   A 1 680 ? 152.317 141.180 177.163 1.00 53.68  ? 706 LEU   A CA  1 
ATOM   5531 C C   . LEU   A 1 680 ? 151.597 140.739 178.431 1.00 57.04  ? 706 LEU   A C   1 
ATOM   5532 O O   . LEU   A 1 680 ? 151.284 141.569 179.292 1.00 55.60  ? 706 LEU   A O   1 
ATOM   5533 C CB  . LEU   A 1 680 ? 151.323 141.265 176.005 1.00 50.35  ? 706 LEU   A CB  1 
ATOM   5534 C CG  . LEU   A 1 680 ? 151.758 141.972 174.724 1.00 52.84  ? 706 LEU   A CG  1 
ATOM   5535 C CD1 . LEU   A 1 680 ? 150.717 141.768 173.640 1.00 46.89  ? 706 LEU   A CD1 1 
ATOM   5536 C CD2 . LEU   A 1 680 ? 151.989 143.456 174.966 1.00 51.50  ? 706 LEU   A CD2 1 
ATOM   5537 N N   . ILE   A 1 681 ? 151.333 139.439 178.569 1.00 59.74  ? 707 ILE   A N   1 
ATOM   5538 C CA  . ILE   A 1 681 ? 150.455 138.974 179.643 1.00 53.91  ? 707 ILE   A CA  1 
ATOM   5539 C C   . ILE   A 1 681 ? 151.234 138.781 180.939 1.00 56.66  ? 707 ILE   A C   1 
ATOM   5540 O O   . ILE   A 1 681 ? 150.933 139.413 181.958 1.00 55.85  ? 707 ILE   A O   1 
ATOM   5541 C CB  . ILE   A 1 681 ? 149.722 137.681 179.232 1.00 51.70  ? 707 ILE   A CB  1 
ATOM   5542 C CG1 . ILE   A 1 681 ? 148.832 137.922 178.005 1.00 51.97  ? 707 ILE   A CG1 1 
ATOM   5543 C CG2 . ILE   A 1 681 ? 148.878 137.171 180.403 1.00 53.81  ? 707 ILE   A CG2 1 
ATOM   5544 C CD1 . ILE   A 1 681 ? 148.329 136.659 177.342 1.00 54.35  ? 707 ILE   A CD1 1 
ATOM   5545 N N   . LEU   A 1 682 ? 152.249 137.914 180.922 1.00 59.19  ? 708 LEU   A N   1 
ATOM   5546 C CA  . LEU   A 1 682 ? 152.948 137.500 182.134 1.00 54.37  ? 708 LEU   A CA  1 
ATOM   5547 C C   . LEU   A 1 682 ? 154.252 138.257 182.373 1.00 56.99  ? 708 LEU   A C   1 
ATOM   5548 O O   . LEU   A 1 682 ? 154.985 137.918 183.307 1.00 58.61  ? 708 LEU   A O   1 
ATOM   5549 C CB  . LEU   A 1 682 ? 153.231 135.995 182.087 1.00 56.42  ? 708 LEU   A CB  1 
ATOM   5550 C CG  . LEU   A 1 682 ? 152.047 135.059 182.334 1.00 61.16  ? 708 LEU   A CG  1 
ATOM   5551 C CD1 . LEU   A 1 682 ? 151.368 134.674 181.030 1.00 60.20  ? 708 LEU   A CD1 1 
ATOM   5552 C CD2 . LEU   A 1 682 ? 152.499 133.816 183.085 1.00 61.45  ? 708 LEU   A CD2 1 
ATOM   5553 N N   . GLY   A 1 683 ? 154.557 139.273 181.570 1.00 60.64  ? 709 GLY   A N   1 
ATOM   5554 C CA  . GLY   A 1 683 ? 155.771 140.043 181.757 1.00 60.89  ? 709 GLY   A CA  1 
ATOM   5555 C C   . GLY   A 1 683 ? 156.951 139.469 181.003 1.00 62.08  ? 709 GLY   A C   1 
ATOM   5556 O O   . GLY   A 1 683 ? 156.889 138.410 180.373 1.00 66.63  ? 709 GLY   A O   1 
ATOM   5557 N N   . ARG   A 1 684 ? 158.067 140.202 181.080 1.00 55.43  ? 710 ARG   A N   1 
ATOM   5558 C CA  . ARG   A 1 684 ? 159.269 139.895 180.317 1.00 58.14  ? 710 ARG   A CA  1 
ATOM   5559 C C   . ARG   A 1 684 ? 160.281 139.168 181.196 1.00 62.98  ? 710 ARG   A C   1 
ATOM   5560 O O   . ARG   A 1 684 ? 160.615 139.684 182.273 1.00 67.44  ? 710 ARG   A O   1 
ATOM   5561 C CB  . ARG   A 1 684 ? 159.886 141.181 179.779 1.00 64.92  ? 710 ARG   A CB  1 
ATOM   5562 C CG  . ARG   A 1 684 ? 160.983 140.957 178.757 1.00 69.36  ? 710 ARG   A CG  1 
ATOM   5563 C CD  . ARG   A 1 684 ? 161.330 142.235 178.010 1.00 70.07  ? 710 ARG   A CD  1 
ATOM   5564 N NE  . ARG   A 1 684 ? 160.247 142.672 177.136 1.00 71.36  ? 710 ARG   A NE  1 
ATOM   5565 C CZ  . ARG   A 1 684 ? 160.312 143.704 176.305 1.00 75.75  ? 710 ARG   A CZ  1 
ATOM   5566 N NH1 . ARG   A 1 684 ? 161.403 144.448 176.200 1.00 77.17  ? 710 ARG   A NH1 1 
ATOM   5567 N NH2 . ARG   A 1 684 ? 159.253 143.998 175.556 1.00 74.11  ? 710 ARG   A NH2 1 
ATOM   5568 N N   . PRO   A 1 685 ? 160.808 137.997 180.832 1.00 60.59  ? 711 PRO   A N   1 
ATOM   5569 C CA  . PRO   A 1 685 ? 161.811 137.342 181.678 1.00 59.47  ? 711 PRO   A CA  1 
ATOM   5570 C C   . PRO   A 1 685 ? 163.164 138.037 181.567 1.00 64.11  ? 711 PRO   A C   1 
ATOM   5571 O O   . PRO   A 1 685 ? 163.315 139.069 180.917 1.00 68.39  ? 711 PRO   A O   1 
ATOM   5572 C CB  . PRO   A 1 685 ? 161.881 135.915 181.126 1.00 60.25  ? 711 PRO   A CB  1 
ATOM   5573 C CG  . PRO   A 1 685 ? 160.725 135.764 180.237 1.00 60.70  ? 711 PRO   A CG  1 
ATOM   5574 C CD  . PRO   A 1 685 ? 160.411 137.114 179.722 1.00 59.32  ? 711 PRO   A CD  1 
ATOM   5575 N N   . SER   A 1 686 ? 164.156 137.446 182.228 1.00 69.51  ? 712 SER   A N   1 
ATOM   5576 C CA  . SER   A 1 686 ? 165.524 137.923 182.105 1.00 72.24  ? 712 SER   A CA  1 
ATOM   5577 C C   . SER   A 1 686 ? 166.007 137.775 180.665 1.00 69.56  ? 712 SER   A C   1 
ATOM   5578 O O   . SER   A 1 686 ? 165.454 137.013 179.868 1.00 69.86  ? 712 SER   A O   1 
ATOM   5579 C CB  . SER   A 1 686 ? 166.446 137.153 183.049 1.00 72.43  ? 712 SER   A CB  1 
ATOM   5580 O OG  . SER   A 1 686 ? 166.028 137.293 184.396 1.00 75.84  ? 712 SER   A OG  1 
ATOM   5581 N N   . LEU   A 1 687 ? 167.064 138.521 180.340 1.00 70.45  ? 713 LEU   A N   1 
ATOM   5582 C CA  . LEU   A 1 687 ? 167.511 138.618 178.955 1.00 70.83  ? 713 LEU   A CA  1 
ATOM   5583 C C   . LEU   A 1 687 ? 168.024 137.285 178.424 1.00 71.06  ? 713 LEU   A C   1 
ATOM   5584 O O   . LEU   A 1 687 ? 167.893 137.009 177.226 1.00 76.21  ? 713 LEU   A O   1 
ATOM   5585 C CB  . LEU   A 1 687 ? 168.602 139.685 178.827 1.00 73.23  ? 713 LEU   A CB  1 
ATOM   5586 C CG  . LEU   A 1 687 ? 168.248 141.171 179.001 1.00 75.56  ? 713 LEU   A CG  1 
ATOM   5587 C CD1 . LEU   A 1 687 ? 167.114 141.592 178.074 1.00 75.52  ? 713 LEU   A CD1 1 
ATOM   5588 C CD2 . LEU   A 1 687 ? 167.914 141.520 180.447 1.00 76.68  ? 713 LEU   A CD2 1 
ATOM   5589 N N   . GLU   A 1 688 ? 168.628 136.461 179.281 1.00 67.90  ? 714 GLU   A N   1 
ATOM   5590 C CA  . GLU   A 1 688 ? 169.207 135.205 178.812 1.00 74.03  ? 714 GLU   A CA  1 
ATOM   5591 C C   . GLU   A 1 688 ? 168.134 134.272 178.262 1.00 75.51  ? 714 GLU   A C   1 
ATOM   5592 O O   . GLU   A 1 688 ? 168.321 133.645 177.211 1.00 76.92  ? 714 GLU   A O   1 
ATOM   5593 C CB  . GLU   A 1 688 ? 169.980 134.537 179.952 1.00 80.58  ? 714 GLU   A CB  1 
ATOM   5594 C CG  . GLU   A 1 688 ? 170.846 133.341 179.533 1.00 83.58  ? 714 GLU   A CG  1 
ATOM   5595 C CD  . GLU   A 1 688 ? 170.099 132.012 179.492 1.00 86.31  ? 714 GLU   A CD  1 
ATOM   5596 O OE1 . GLU   A 1 688 ? 168.941 131.942 179.956 1.00 84.64  ? 714 GLU   A OE1 1 
ATOM   5597 O OE2 . GLU   A 1 688 ? 170.681 131.028 178.989 1.00 84.94  ? 714 GLU   A OE2 1 
ATOM   5598 N N   . GLN   A 1 689 ? 167.002 134.165 178.961 1.00 69.52  ? 715 GLN   A N   1 
ATOM   5599 C CA  . GLN   A 1 689 ? 165.922 133.311 178.482 1.00 63.70  ? 715 GLN   A CA  1 
ATOM   5600 C C   . GLN   A 1 689 ? 165.352 133.839 177.174 1.00 65.59  ? 715 GLN   A C   1 
ATOM   5601 O O   . GLN   A 1 689 ? 165.013 133.057 176.277 1.00 69.96  ? 715 GLN   A O   1 
ATOM   5602 C CB  . GLN   A 1 689 ? 164.834 133.206 179.546 1.00 63.52  ? 715 GLN   A CB  1 
ATOM   5603 C CG  . GLN   A 1 689 ? 163.951 131.987 179.408 1.00 67.49  ? 715 GLN   A CG  1 
ATOM   5604 C CD  . GLN   A 1 689 ? 162.895 131.915 180.491 1.00 74.15  ? 715 GLN   A CD  1 
ATOM   5605 O OE1 . GLN   A 1 689 ? 162.774 132.819 181.316 1.00 71.56  ? 715 GLN   A OE1 1 
ATOM   5606 N NE2 . GLN   A 1 689 ? 162.124 130.834 180.494 1.00 76.23  ? 715 GLN   A NE2 1 
ATOM   5607 N N   . LEU   A 1 690 ? 165.236 135.162 177.047 1.00 64.43  ? 716 LEU   A N   1 
ATOM   5608 C CA  . LEU   A 1 690 ? 164.782 135.747 175.790 1.00 62.94  ? 716 LEU   A CA  1 
ATOM   5609 C C   . LEU   A 1 690 ? 165.734 135.413 174.653 1.00 62.01  ? 716 LEU   A C   1 
ATOM   5610 O O   . LEU   A 1 690 ? 165.296 135.090 173.543 1.00 66.77  ? 716 LEU   A O   1 
ATOM   5611 C CB  . LEU   A 1 690 ? 164.641 137.262 175.927 1.00 63.72  ? 716 LEU   A CB  1 
ATOM   5612 C CG  . LEU   A 1 690 ? 163.284 137.809 176.366 1.00 67.28  ? 716 LEU   A CG  1 
ATOM   5613 C CD1 . LEU   A 1 690 ? 163.425 139.271 176.745 1.00 67.62  ? 716 LEU   A CD1 1 
ATOM   5614 C CD2 . LEU   A 1 690 ? 162.241 137.640 175.270 1.00 63.76  ? 716 LEU   A CD2 1 
ATOM   5615 N N   . ALA   A 1 691 ? 167.040 135.499 174.904 1.00 61.93  ? 717 ALA   A N   1 
ATOM   5616 C CA  . ALA   A 1 691 ? 168.010 135.161 173.868 1.00 67.11  ? 717 ALA   A CA  1 
ATOM   5617 C C   . ALA   A 1 691 ? 167.893 133.697 173.467 1.00 65.83  ? 717 ALA   A C   1 
ATOM   5618 O O   . ALA   A 1 691 ? 167.944 133.363 172.276 1.00 68.80  ? 717 ALA   A O   1 
ATOM   5619 C CB  . ALA   A 1 691 ? 169.425 135.474 174.351 1.00 70.45  ? 717 ALA   A CB  1 
ATOM   5620 N N   . GLN   A 1 692 ? 167.734 132.811 174.451 1.00 63.12  ? 718 GLN   A N   1 
ATOM   5621 C CA  . GLN   A 1 692 ? 167.569 131.394 174.147 1.00 65.29  ? 718 GLN   A CA  1 
ATOM   5622 C C   . GLN   A 1 692 ? 166.324 131.161 173.299 1.00 65.65  ? 718 GLN   A C   1 
ATOM   5623 O O   . GLN   A 1 692 ? 166.359 130.404 172.322 1.00 66.78  ? 718 GLN   A O   1 
ATOM   5624 C CB  . GLN   A 1 692 ? 167.501 130.592 175.449 1.00 70.06  ? 718 GLN   A CB  1 
ATOM   5625 C CG  . GLN   A 1 692 ? 167.374 129.077 175.287 1.00 73.34  ? 718 GLN   A CG  1 
ATOM   5626 C CD  . GLN   A 1 692 ? 168.578 128.450 174.613 1.00 80.89  ? 718 GLN   A CD  1 
ATOM   5627 O OE1 . GLN   A 1 692 ? 169.612 129.094 174.436 1.00 82.36  ? 718 GLN   A OE1 1 
ATOM   5628 N NE2 . GLN   A 1 692 ? 168.451 127.182 174.237 1.00 78.94  ? 718 GLN   A NE2 1 
ATOM   5629 N N   . GLU   A 1 693 ? 165.217 131.819 173.647 1.00 63.97  ? 719 GLU   A N   1 
ATOM   5630 C CA  . GLU   A 1 693 ? 163.987 131.639 172.884 1.00 62.39  ? 719 GLU   A CA  1 
ATOM   5631 C C   . GLU   A 1 693 ? 164.135 132.159 171.461 1.00 61.04  ? 719 GLU   A C   1 
ATOM   5632 O O   . GLU   A 1 693 ? 163.676 131.518 170.509 1.00 58.62  ? 719 GLU   A O   1 
ATOM   5633 C CB  . GLU   A 1 693 ? 162.828 132.335 173.591 1.00 64.10  ? 719 GLU   A CB  1 
ATOM   5634 C CG  . GLU   A 1 693 ? 162.360 131.613 174.836 1.00 61.45  ? 719 GLU   A CG  1 
ATOM   5635 C CD  . GLU   A 1 693 ? 161.151 132.260 175.461 1.00 63.17  ? 719 GLU   A CD  1 
ATOM   5636 O OE1 . GLU   A 1 693 ? 160.841 133.413 175.100 1.00 65.80  ? 719 GLU   A OE1 1 
ATOM   5637 O OE2 . GLU   A 1 693 ? 160.506 131.616 176.315 1.00 65.61  ? 719 GLU   A OE2 1 
ATOM   5638 N N   . VAL   A 1 694 ? 164.761 133.325 171.296 1.00 63.95  ? 720 VAL   A N   1 
ATOM   5639 C CA  . VAL   A 1 694 ? 164.922 133.894 169.962 1.00 62.34  ? 720 VAL   A CA  1 
ATOM   5640 C C   . VAL   A 1 694 ? 165.819 133.004 169.115 1.00 61.53  ? 720 VAL   A C   1 
ATOM   5641 O O   . VAL   A 1 694 ? 165.601 132.849 167.908 1.00 64.57  ? 720 VAL   A O   1 
ATOM   5642 C CB  . VAL   A 1 694 ? 165.462 135.332 170.055 1.00 64.63  ? 720 VAL   A CB  1 
ATOM   5643 C CG1 . VAL   A 1 694 ? 165.893 135.841 168.684 1.00 65.36  ? 720 VAL   A CG1 1 
ATOM   5644 C CG2 . VAL   A 1 694 ? 164.407 136.253 170.646 1.00 64.89  ? 720 VAL   A CG2 1 
ATOM   5645 N N   . THR   A 1 695 ? 166.845 132.409 169.728 1.00 64.24  ? 721 THR   A N   1 
ATOM   5646 C CA  . THR   A 1 695 ? 167.655 131.431 169.009 1.00 68.48  ? 721 THR   A CA  1 
ATOM   5647 C C   . THR   A 1 695 ? 166.823 130.216 168.615 1.00 68.39  ? 721 THR   A C   1 
ATOM   5648 O O   . THR   A 1 695 ? 166.986 129.670 167.518 1.00 65.32  ? 721 THR   A O   1 
ATOM   5649 C CB  . THR   A 1 695 ? 168.848 131.007 169.863 1.00 71.68  ? 721 THR   A CB  1 
ATOM   5650 O OG1 . THR   A 1 695 ? 169.678 132.145 170.131 1.00 73.26  ? 721 THR   A OG1 1 
ATOM   5651 C CG2 . THR   A 1 695 ? 169.666 129.939 169.149 1.00 68.32  ? 721 THR   A CG2 1 
ATOM   5652 N N   . TYR   A 1 696 ? 165.932 129.774 169.506 1.00 69.22  ? 722 TYR   A N   1 
ATOM   5653 C CA  . TYR   A 1 696 ? 165.099 128.609 169.218 1.00 65.75  ? 722 TYR   A CA  1 
ATOM   5654 C C   . TYR   A 1 696 ? 164.149 128.870 168.055 1.00 66.55  ? 722 TYR   A C   1 
ATOM   5655 O O   . TYR   A 1 696 ? 163.959 128.005 167.193 1.00 68.41  ? 722 TYR   A O   1 
ATOM   5656 C CB  . TYR   A 1 696 ? 164.314 128.214 170.467 1.00 64.09  ? 722 TYR   A CB  1 
ATOM   5657 C CG  . TYR   A 1 696 ? 163.242 127.181 170.223 1.00 58.52  ? 722 TYR   A CG  1 
ATOM   5658 C CD1 . TYR   A 1 696 ? 163.566 125.848 170.031 1.00 57.04  ? 722 TYR   A CD1 1 
ATOM   5659 C CD2 . TYR   A 1 696 ? 161.903 127.537 170.199 1.00 56.81  ? 722 TYR   A CD2 1 
ATOM   5660 C CE1 . TYR   A 1 696 ? 162.589 124.904 169.815 1.00 55.99  ? 722 TYR   A CE1 1 
ATOM   5661 C CE2 . TYR   A 1 696 ? 160.922 126.600 169.983 1.00 54.53  ? 722 TYR   A CE2 1 
ATOM   5662 C CZ  . TYR   A 1 696 ? 161.270 125.286 169.792 1.00 56.34  ? 722 TYR   A CZ  1 
ATOM   5663 O OH  . TYR   A 1 696 ? 160.291 124.344 169.575 1.00 58.62  ? 722 TYR   A OH  1 
ATOM   5664 N N   . ALA   A 1 697 ? 163.535 130.055 168.022 1.00 64.33  ? 723 ALA   A N   1 
ATOM   5665 C CA  . ALA   A 1 697 ? 162.550 130.356 166.986 1.00 57.75  ? 723 ALA   A CA  1 
ATOM   5666 C C   . ALA   A 1 697 ? 163.183 130.380 165.600 1.00 60.82  ? 723 ALA   A C   1 
ATOM   5667 O O   . ALA   A 1 697 ? 162.611 129.852 164.640 1.00 58.77  ? 723 ALA   A O   1 
ATOM   5668 C CB  . ALA   A 1 697 ? 161.877 131.694 167.286 1.00 57.68  ? 723 ALA   A CB  1 
ATOM   5669 N N   . ASN   A 1 698 ? 164.365 130.984 165.475 1.00 63.48  ? 724 ASN   A N   1 
ATOM   5670 C CA  . ASN   A 1 698 ? 165.009 131.131 164.176 1.00 61.65  ? 724 ASN   A CA  1 
ATOM   5671 C C   . ASN   A 1 698 ? 165.579 129.827 163.635 1.00 65.23  ? 724 ASN   A C   1 
ATOM   5672 O O   . ASN   A 1 698 ? 166.055 129.816 162.496 1.00 70.90  ? 724 ASN   A O   1 
ATOM   5673 C CB  . ASN   A 1 698 ? 166.127 132.172 164.259 1.00 60.95  ? 724 ASN   A CB  1 
ATOM   5674 C CG  . ASN   A 1 698 ? 165.598 133.583 164.420 1.00 66.73  ? 724 ASN   A CG  1 
ATOM   5675 O OD1 . ASN   A 1 698 ? 164.543 133.927 163.892 1.00 67.31  ? 724 ASN   A OD1 1 
ATOM   5676 N ND2 . ASN   A 1 698 ? 166.335 134.410 165.151 1.00 68.28  ? 724 ASN   A ND2 1 
ATOM   5677 N N   . LEU   A 1 699 ? 165.566 128.749 164.416 1.00 65.19  ? 725 LEU   A N   1 
ATOM   5678 C CA  . LEU   A 1 699 ? 166.141 127.490 163.963 1.00 65.71  ? 725 LEU   A CA  1 
ATOM   5679 C C   . LEU   A 1 699 ? 165.416 126.982 162.724 1.00 71.13  ? 725 LEU   A C   1 
ATOM   5680 O O   . LEU   A 1 699 ? 164.185 126.996 162.655 1.00 73.71  ? 725 LEU   A O   1 
ATOM   5681 C CB  . LEU   A 1 699 ? 166.069 126.450 165.081 1.00 66.04  ? 725 LEU   A CB  1 
ATOM   5682 C CG  . LEU   A 1 699 ? 166.617 125.050 164.787 1.00 73.32  ? 725 LEU   A CG  1 
ATOM   5683 C CD1 . LEU   A 1 699 ? 168.076 125.104 164.358 1.00 72.61  ? 725 LEU   A CD1 1 
ATOM   5684 C CD2 . LEU   A 1 699 ? 166.453 124.157 166.008 1.00 74.37  ? 725 LEU   A CD2 1 
ATOM   5685 N N   . ARG   A 1 700 ? 166.190 126.537 161.741 1.00 73.92  ? 726 ARG   A N   1 
ATOM   5686 C CA  . ARG   A 1 700 ? 165.600 125.975 160.536 1.00 78.48  ? 726 ARG   A CA  1 
ATOM   5687 C C   . ARG   A 1 700 ? 164.885 124.668 160.888 1.00 80.85  ? 726 ARG   A C   1 
ATOM   5688 O O   . ARG   A 1 700 ? 165.353 123.931 161.761 1.00 84.37  ? 726 ARG   A O   1 
ATOM   5689 C CB  . ARG   A 1 700 ? 166.680 125.719 159.482 1.00 81.22  ? 726 ARG   A CB  1 
ATOM   5690 C CG  . ARG   A 1 700 ? 166.281 126.058 158.055 1.00 81.41  ? 726 ARG   A CG  1 
ATOM   5691 C CD  . ARG   A 1 700 ? 166.264 127.559 157.809 1.00 83.19  ? 726 ARG   A CD  1 
ATOM   5692 N NE  . ARG   A 1 700 ? 165.858 127.879 156.444 1.00 90.34  ? 726 ARG   A NE  1 
ATOM   5693 C CZ  . ARG   A 1 700 ? 165.637 129.103 155.983 1.00 91.41  ? 726 ARG   A CZ  1 
ATOM   5694 N NH1 . ARG   A 1 700 ? 165.765 130.173 156.753 1.00 87.53  ? 726 ARG   A NH1 1 
ATOM   5695 N NH2 . ARG   A 1 700 ? 165.275 129.260 154.712 1.00 89.13  ? 726 ARG   A NH2 1 
ATOM   5696 N N   . PRO   A 1 701 ? 163.744 124.355 160.253 1.00 73.59  ? 727 PRO   A N   1 
ATOM   5697 C CA  . PRO   A 1 701 ? 163.016 123.142 160.676 1.00 73.09  ? 727 PRO   A CA  1 
ATOM   5698 C C   . PRO   A 1 701 ? 163.792 121.851 160.469 1.00 87.55  ? 727 PRO   A C   1 
ATOM   5699 O O   . PRO   A 1 701 ? 163.917 121.054 161.408 1.00 90.73  ? 727 PRO   A O   1 
ATOM   5700 C CB  . PRO   A 1 701 ? 161.742 123.185 159.821 1.00 73.92  ? 727 PRO   A CB  1 
ATOM   5701 C CG  . PRO   A 1 701 ? 161.599 124.584 159.407 1.00 72.44  ? 727 PRO   A CG  1 
ATOM   5702 C CD  . PRO   A 1 701 ? 162.979 125.099 159.236 1.00 74.10  ? 727 PRO   A CD  1 
ATOM   5703 N N   . PHE   A 1 702 ? 164.324 121.626 159.269 1.00 96.24  ? 728 PHE   A N   1 
ATOM   5704 C CA  . PHE   A 1 702 ? 164.966 120.358 158.907 1.00 96.97  ? 728 PHE   A CA  1 
ATOM   5705 C C   . PHE   A 1 702 ? 164.043 119.170 159.168 1.00 93.73  ? 728 PHE   A C   1 
ATOM   5706 O O   . PHE   A 1 702 ? 162.820 119.309 159.183 1.00 90.84  ? 728 PHE   A O   1 
ATOM   5707 C CB  . PHE   A 1 702 ? 166.284 120.164 159.667 1.00 96.71  ? 728 PHE   A CB  1 
ATOM   5708 C CG  . PHE   A 1 702 ? 167.423 120.983 159.131 1.00 99.44  ? 728 PHE   A CG  1 
ATOM   5709 C CD1 . PHE   A 1 702 ? 168.013 120.664 157.919 1.00 100.70 ? 728 PHE   A CD1 1 
ATOM   5710 C CD2 . PHE   A 1 702 ? 167.917 122.059 159.847 1.00 97.00  ? 728 PHE   A CD2 1 
ATOM   5711 C CE1 . PHE   A 1 702 ? 169.065 121.411 157.425 1.00 102.07 ? 728 PHE   A CE1 1 
ATOM   5712 C CE2 . PHE   A 1 702 ? 168.972 122.809 159.359 1.00 98.30  ? 728 PHE   A CE2 1 
ATOM   5713 C CZ  . PHE   A 1 702 ? 169.545 122.485 158.147 1.00 102.85 ? 728 PHE   A CZ  1 
ATOM   5714 N N   . LEU   B 2 5   ? 179.311 153.412 163.236 1.00 67.91  ? 23  LEU   P N   1 
ATOM   5715 C CA  . LEU   B 2 5   ? 178.471 153.299 162.050 1.00 67.46  ? 23  LEU   P CA  1 
ATOM   5716 C C   . LEU   B 2 5   ? 178.926 154.315 160.994 1.00 67.69  ? 23  LEU   P C   1 
ATOM   5717 O O   . LEU   B 2 5   ? 179.668 153.962 160.077 1.00 67.93  ? 23  LEU   P O   1 
ATOM   5718 C CB  . LEU   B 2 5   ? 176.996 153.490 162.428 1.00 66.64  ? 23  LEU   P CB  1 
ATOM   5719 C CG  . LEU   B 2 5   ? 175.945 153.406 161.319 1.00 65.72  ? 23  LEU   P CG  1 
ATOM   5720 C CD1 . LEU   B 2 5   ? 175.967 152.044 160.642 1.00 65.34  ? 23  LEU   P CD1 1 
ATOM   5721 C CD2 . LEU   B 2 5   ? 174.561 153.704 161.879 1.00 65.11  ? 23  LEU   P CD2 1 
ATOM   5722 N N   . ASP   B 2 6   ? 178.491 155.571 161.129 1.00 66.69  ? 24  ASP   P N   1 
ATOM   5723 C CA  . ASP   B 2 6   ? 178.922 156.662 160.251 1.00 60.96  ? 24  ASP   P CA  1 
ATOM   5724 C C   . ASP   B 2 6   ? 178.591 156.384 158.785 1.00 56.51  ? 24  ASP   P C   1 
ATOM   5725 O O   . ASP   B 2 6   ? 179.295 156.838 157.880 1.00 50.66  ? 24  ASP   P O   1 
ATOM   5726 C CB  . ASP   B 2 6   ? 180.420 156.936 160.418 1.00 63.40  ? 24  ASP   P CB  1 
ATOM   5727 C CG  . ASP   B 2 6   ? 180.827 158.312 159.917 1.00 66.15  ? 24  ASP   P CG  1 
ATOM   5728 O OD1 . ASP   B 2 6   ? 179.978 159.015 159.330 1.00 57.99  ? 24  ASP   P OD1 1 
ATOM   5729 O OD2 . ASP   B 2 6   ? 182.001 158.691 160.113 1.00 65.54  ? 24  ASP   P OD2 1 
ATOM   5730 N N   . SER   B 2 7   ? 177.520 155.631 158.541 1.00 54.75  ? 25  SER   P N   1 
ATOM   5731 C CA  . SER   B 2 7   ? 177.020 155.376 157.198 1.00 50.11  ? 25  SER   P CA  1 
ATOM   5732 C C   . SER   B 2 7   ? 175.955 156.375 156.770 1.00 49.59  ? 25  SER   P C   1 
ATOM   5733 O O   . SER   B 2 7   ? 175.406 156.240 155.673 1.00 52.19  ? 25  SER   P O   1 
ATOM   5734 C CB  . SER   B 2 7   ? 176.451 153.959 157.112 1.00 51.55  ? 25  SER   P CB  1 
ATOM   5735 O OG  . SER   B 2 7   ? 177.429 152.998 157.462 1.00 57.67  ? 25  SER   P OG  1 
ATOM   5736 N N   . VAL   B 2 8   ? 175.646 157.369 157.605 1.00 45.96  ? 26  VAL   P N   1 
ATOM   5737 C CA  . VAL   B 2 8   ? 174.656 158.370 157.232 1.00 40.48  ? 26  VAL   P CA  1 
ATOM   5738 C C   . VAL   B 2 8   ? 175.202 159.275 156.135 1.00 44.40  ? 26  VAL   P C   1 
ATOM   5739 O O   . VAL   B 2 8   ? 174.498 159.596 155.170 1.00 47.73  ? 26  VAL   P O   1 
ATOM   5740 C CB  . VAL   B 2 8   ? 174.228 159.177 158.471 1.00 41.65  ? 26  VAL   P CB  1 
ATOM   5741 C CG1 . VAL   B 2 8   ? 173.188 160.225 158.091 1.00 44.82  ? 26  VAL   P CG1 1 
ATOM   5742 C CG2 . VAL   B 2 8   ? 173.697 158.246 159.555 1.00 47.77  ? 26  VAL   P CG2 1 
ATOM   5743 N N   . PHE   B 2 9   ? 176.456 159.694 156.260 1.00 44.21  ? 27  PHE   P N   1 
ATOM   5744 C CA  . PHE   B 2 9   ? 177.084 160.625 155.336 1.00 38.08  ? 27  PHE   P CA  1 
ATOM   5745 C C   . PHE   B 2 9   ? 177.864 159.883 154.259 1.00 37.95  ? 27  PHE   P C   1 
ATOM   5746 O O   . PHE   B 2 9   ? 178.294 158.742 154.442 1.00 44.32  ? 27  PHE   P O   1 
ATOM   5747 C CB  . PHE   B 2 9   ? 178.022 161.573 156.082 1.00 38.69  ? 27  PHE   P CB  1 
ATOM   5748 C CG  . PHE   B 2 9   ? 177.370 162.305 157.215 1.00 37.96  ? 27  PHE   P CG  1 
ATOM   5749 C CD1 . PHE   B 2 9   ? 176.574 163.403 156.977 1.00 36.94  ? 27  PHE   P CD1 1 
ATOM   5750 C CD2 . PHE   B 2 9   ? 177.569 161.903 158.519 1.00 42.89  ? 27  PHE   P CD2 1 
ATOM   5751 C CE1 . PHE   B 2 9   ? 175.979 164.080 158.013 1.00 37.49  ? 27  PHE   P CE1 1 
ATOM   5752 C CE2 . PHE   B 2 9   ? 176.976 162.577 159.561 1.00 42.96  ? 27  PHE   P CE2 1 
ATOM   5753 C CZ  . PHE   B 2 9   ? 176.181 163.669 159.305 1.00 38.98  ? 27  PHE   P CZ  1 
ATOM   5754 N N   . SER   B 2 10  ? 178.033 160.554 153.120 1.00 35.82  ? 28  SER   P N   1 
ATOM   5755 C CA  . SER   B 2 10  ? 178.849 160.056 152.019 1.00 34.49  ? 28  SER   P CA  1 
ATOM   5756 C C   . SER   B 2 10  ? 179.838 161.131 151.590 1.00 36.67  ? 28  SER   P C   1 
ATOM   5757 O O   . SER   B 2 10  ? 179.917 162.188 152.222 1.00 40.52  ? 28  SER   P O   1 
ATOM   5758 C CB  . SER   B 2 10  ? 177.973 159.633 150.842 1.00 33.59  ? 28  SER   P CB  1 
ATOM   5759 O OG  . SER   B 2 10  ? 178.766 159.170 149.767 1.00 36.37  ? 28  SER   P OG  1 
ATOM   5760 N N   . SER   B 2 11  ? 180.587 160.875 150.520 1.00 34.87  ? 29  SER   P N   1 
ATOM   5761 C CA  . SER   B 2 11  ? 181.637 161.762 150.048 1.00 35.13  ? 29  SER   P CA  1 
ATOM   5762 C C   . SER   B 2 11  ? 181.252 162.370 148.707 1.00 38.08  ? 29  SER   P C   1 
ATOM   5763 O O   . SER   B 2 11  ? 180.397 161.851 147.984 1.00 38.80  ? 29  SER   P O   1 
ATOM   5764 C CB  . SER   B 2 11  ? 182.966 161.015 149.914 1.00 38.24  ? 29  SER   P CB  1 
ATOM   5765 O OG  . SER   B 2 11  ? 182.868 159.974 148.959 1.00 43.26  ? 29  SER   P OG  1 
ATOM   5766 N N   . SER   B 2 12  ? 181.898 163.492 148.387 1.00 38.52  ? 30  SER   P N   1 
ATOM   5767 C CA  . SER   B 2 12  ? 181.638 164.156 147.115 1.00 37.36  ? 30  SER   P CA  1 
ATOM   5768 C C   . SER   B 2 12  ? 182.028 163.270 145.942 1.00 37.41  ? 30  SER   P C   1 
ATOM   5769 O O   . SER   B 2 12  ? 181.364 163.277 144.900 1.00 40.85  ? 30  SER   P O   1 
ATOM   5770 C CB  . SER   B 2 12  ? 182.393 165.481 147.053 1.00 39.74  ? 30  SER   P CB  1 
ATOM   5771 O OG  . SER   B 2 12  ? 182.266 166.076 145.774 1.00 42.77  ? 30  SER   P OG  1 
ATOM   5772 N N   . GLU   B 2 13  ? 183.110 162.506 146.091 1.00 36.40  ? 31  GLU   P N   1 
ATOM   5773 C CA  . GLU   B 2 13  ? 183.568 161.655 145.001 1.00 37.16  ? 31  GLU   P CA  1 
ATOM   5774 C C   . GLU   B 2 13  ? 182.555 160.565 144.677 1.00 35.44  ? 31  GLU   P C   1 
ATOM   5775 O O   . GLU   B 2 13  ? 182.289 160.289 143.502 1.00 36.34  ? 31  GLU   P O   1 
ATOM   5776 C CB  . GLU   B 2 13  ? 184.918 161.036 145.357 1.00 40.72  ? 31  GLU   P CB  1 
ATOM   5777 C CG  . GLU   B 2 13  ? 186.014 162.051 145.622 1.00 43.08  ? 31  GLU   P CG  1 
ATOM   5778 C CD  . GLU   B 2 13  ? 187.351 161.398 145.903 1.00 51.81  ? 31  GLU   P CD  1 
ATOM   5779 O OE1 . GLU   B 2 13  ? 187.415 160.151 145.897 1.00 54.43  ? 31  GLU   P OE1 1 
ATOM   5780 O OE2 . GLU   B 2 13  ? 188.337 162.129 146.130 1.00 54.95  ? 31  GLU   P OE2 1 
ATOM   5781 N N   . ARG   B 2 14  ? 181.979 159.934 145.697 1.00 35.80  ? 32  ARG   P N   1 
ATOM   5782 C CA  . ARG   B 2 14  ? 181.053 158.829 145.487 1.00 35.92  ? 32  ARG   P CA  1 
ATOM   5783 C C   . ARG   B 2 14  ? 179.607 159.273 145.316 1.00 33.89  ? 32  ARG   P C   1 
ATOM   5784 O O   . ARG   B 2 14  ? 178.758 158.434 144.998 1.00 36.41  ? 32  ARG   P O   1 
ATOM   5785 C CB  . ARG   B 2 14  ? 181.134 157.839 146.653 1.00 38.38  ? 32  ARG   P CB  1 
ATOM   5786 C CG  . ARG   B 2 14  ? 182.473 157.129 146.774 1.00 43.86  ? 32  ARG   P CG  1 
ATOM   5787 C CD  . ARG   B 2 14  ? 182.440 156.054 147.850 1.00 46.73  ? 32  ARG   P CD  1 
ATOM   5788 N NE  . ARG   B 2 14  ? 182.225 156.610 149.183 1.00 46.66  ? 32  ARG   P NE  1 
ATOM   5789 C CZ  . ARG   B 2 14  ? 183.172 157.119 149.961 1.00 48.88  ? 32  ARG   P CZ  1 
ATOM   5790 N NH1 . ARG   B 2 14  ? 184.437 157.188 149.571 1.00 49.02  ? 32  ARG   P NH1 1 
ATOM   5791 N NH2 . ARG   B 2 14  ? 182.842 157.578 151.166 1.00 47.73  ? 32  ARG   P NH2 1 
ATOM   5792 N N   . ALA   B 2 15  ? 179.301 160.553 145.519 1.00 31.56  ? 33  ALA   P N   1 
ATOM   5793 C CA  . ALA   B 2 15  ? 177.956 161.062 145.291 1.00 31.05  ? 33  ALA   P CA  1 
ATOM   5794 C C   . ALA   B 2 15  ? 177.744 161.484 143.846 1.00 35.01  ? 33  ALA   P C   1 
ATOM   5795 O O   . ALA   B 2 15  ? 176.660 161.275 143.293 1.00 37.60  ? 33  ALA   P O   1 
ATOM   5796 C CB  . ALA   B 2 15  ? 177.680 162.242 146.221 1.00 35.04  ? 33  ALA   P CB  1 
ATOM   5797 N N   . HIS   B 2 16  ? 178.763 162.070 143.225 1.00 34.20  ? 34  HIS   P N   1 
ATOM   5798 C CA  . HIS   B 2 16  ? 178.673 162.576 141.858 1.00 33.48  ? 34  HIS   P CA  1 
ATOM   5799 C C   . HIS   B 2 16  ? 179.109 161.535 140.832 1.00 34.93  ? 34  HIS   P C   1 
ATOM   5800 O O   . HIS   B 2 16  ? 179.940 161.814 139.973 1.00 39.00  ? 34  HIS   P O   1 
ATOM   5801 C CB  . HIS   B 2 16  ? 179.518 163.835 141.729 1.00 34.20  ? 34  HIS   P CB  1 
ATOM   5802 C CG  . HIS   B 2 16  ? 179.038 164.979 142.563 1.00 34.44  ? 34  HIS   P CG  1 
ATOM   5803 N ND1 . HIS   B 2 16  ? 179.899 165.862 143.175 1.00 33.32  ? 34  HIS   P ND1 1 
ATOM   5804 C CD2 . HIS   B 2 16  ? 177.789 165.398 142.868 1.00 36.94  ? 34  HIS   P CD2 1 
ATOM   5805 C CE1 . HIS   B 2 16  ? 179.201 166.770 143.830 1.00 36.28  ? 34  HIS   P CE1 1 
ATOM   5806 N NE2 . HIS   B 2 16  ? 177.918 166.512 143.659 1.00 40.53  ? 34  HIS   P NE2 1 
ATOM   5807 N N   . GLN   B 2 17  ? 178.532 160.339 140.889 1.00 34.09  ? 35  GLN   P N   1 
ATOM   5808 C CA  . GLN   B 2 17  ? 178.842 159.259 139.953 1.00 34.02  ? 35  GLN   P CA  1 
ATOM   5809 C C   . GLN   B 2 17  ? 177.547 158.833 139.277 1.00 39.58  ? 35  GLN   P C   1 
ATOM   5810 O O   . GLN   B 2 17  ? 176.876 157.900 139.724 1.00 43.89  ? 35  GLN   P O   1 
ATOM   5811 C CB  . GLN   B 2 17  ? 179.501 158.090 140.659 1.00 38.25  ? 35  GLN   P CB  1 
ATOM   5812 C CG  . GLN   B 2 17  ? 180.922 158.360 141.101 1.00 36.60  ? 35  GLN   P CG  1 
ATOM   5813 C CD  . GLN   B 2 17  ? 181.698 157.094 141.401 1.00 35.99  ? 35  GLN   P CD  1 
ATOM   5814 O OE1 . GLN   B 2 17  ? 181.494 156.060 140.769 1.00 34.56  ? 35  GLN   P OE1 1 
ATOM   5815 N NE2 . GLN   B 2 17  ? 182.601 157.172 142.369 1.00 39.82  ? 35  GLN   P NE2 1 
ATOM   5816 N N   . VAL   B 2 18  ? 177.203 159.514 138.186 1.00 42.67  ? 36  VAL   P N   1 
ATOM   5817 C CA  . VAL   B 2 18  ? 176.046 159.107 137.402 1.00 42.92  ? 36  VAL   P CA  1 
ATOM   5818 C C   . VAL   B 2 18  ? 176.329 157.782 136.712 1.00 50.40  ? 36  VAL   P C   1 
ATOM   5819 O O   . VAL   B 2 18  ? 175.465 156.899 136.644 1.00 55.84  ? 36  VAL   P O   1 
ATOM   5820 C CB  . VAL   B 2 18  ? 175.669 160.207 136.392 1.00 39.85  ? 36  VAL   P CB  1 
ATOM   5821 C CG1 . VAL   B 2 18  ? 174.434 159.800 135.602 1.00 42.25  ? 36  VAL   P CG1 1 
ATOM   5822 C CG2 . VAL   B 2 18  ? 175.440 161.530 137.104 1.00 42.13  ? 36  VAL   P CG2 1 
ATOM   5823 N N   . LEU   B 2 19  ? 177.545 157.621 136.199 1.00 50.23  ? 37  LEU   P N   1 
ATOM   5824 C CA  . LEU   B 2 19  ? 177.955 156.422 135.475 1.00 48.48  ? 37  LEU   P CA  1 
ATOM   5825 C C   . LEU   B 2 19  ? 178.467 155.400 136.480 1.00 53.03  ? 37  LEU   P C   1 
ATOM   5826 O O   . LEU   B 2 19  ? 179.659 155.337 136.779 1.00 55.67  ? 37  LEU   P O   1 
ATOM   5827 C CB  . LEU   B 2 19  ? 179.021 156.765 134.443 1.00 49.41  ? 37  LEU   P CB  1 
ATOM   5828 C CG  . LEU   B 2 19  ? 178.575 157.344 133.098 1.00 51.69  ? 37  LEU   P CG  1 
ATOM   5829 C CD1 . LEU   B 2 19  ? 177.756 158.611 133.248 1.00 51.63  ? 37  LEU   P CD1 1 
ATOM   5830 C CD2 . LEU   B 2 19  ? 179.796 157.604 132.230 1.00 54.43  ? 37  LEU   P CD2 1 
ATOM   5831 N N   . ARG   B 2 20  ? 177.551 154.599 137.019 1.00 58.85  ? 38  ARG   P N   1 
ATOM   5832 C CA  . ARG   B 2 20  ? 177.890 153.438 137.835 1.00 66.28  ? 38  ARG   P CA  1 
ATOM   5833 C C   . ARG   B 2 20  ? 177.095 152.256 137.309 1.00 76.05  ? 38  ARG   P C   1 
ATOM   5834 O O   . ARG   B 2 20  ? 175.863 152.307 137.268 1.00 80.42  ? 38  ARG   P O   1 
ATOM   5835 C CB  . ARG   B 2 20  ? 177.584 153.673 139.317 1.00 64.11  ? 38  ARG   P CB  1 
ATOM   5836 C CG  . ARG   B 2 20  ? 178.108 152.576 140.235 1.00 64.87  ? 38  ARG   P CG  1 
ATOM   5837 C CD  . ARG   B 2 20  ? 177.558 152.686 141.651 1.00 66.18  ? 38  ARG   P CD  1 
ATOM   5838 N NE  . ARG   B 2 20  ? 178.097 153.828 142.386 1.00 62.63  ? 38  ARG   P NE  1 
ATOM   5839 C CZ  . ARG   B 2 20  ? 177.564 155.044 142.427 1.00 59.63  ? 38  ARG   P CZ  1 
ATOM   5840 N NH1 . ARG   B 2 20  ? 176.466 155.352 141.753 1.00 61.86  ? 38  ARG   P NH1 1 
ATOM   5841 N NH2 . ARG   B 2 20  ? 178.151 155.981 143.166 1.00 49.96  ? 38  ARG   P NH2 1 
ATOM   5842 N N   . ILE   B 2 21  ? 177.797 151.202 136.897 1.00 83.68  ? 39  ILE   P N   1 
ATOM   5843 C CA  . ILE   B 2 21  ? 177.131 150.019 136.368 1.00 91.51  ? 39  ILE   P CA  1 
ATOM   5844 C C   . ILE   B 2 21  ? 176.361 149.334 137.488 1.00 94.65  ? 39  ILE   P C   1 
ATOM   5845 O O   . ILE   B 2 21  ? 176.844 149.225 138.624 1.00 94.02  ? 39  ILE   P O   1 
ATOM   5846 C CB  . ILE   B 2 21  ? 178.152 149.060 135.728 1.00 94.62  ? 39  ILE   P CB  1 
ATOM   5847 C CG1 . ILE   B 2 21  ? 178.887 149.739 134.560 1.00 92.51  ? 39  ILE   P CG1 1 
ATOM   5848 C CG2 . ILE   B 2 21  ? 177.444 147.783 135.263 1.00 94.10  ? 39  ILE   P CG2 1 
ATOM   5849 C CD1 . ILE   B 2 21  ? 180.107 148.980 134.061 1.00 90.35  ? 39  ILE   P CD1 1 
ATOM   5850 N N   . ARG   B 2 22  ? 175.153 148.867 137.175 1.00 98.78  ? 40  ARG   P N   1 
ATOM   5851 C CA  . ARG   B 2 22  ? 174.329 148.156 138.142 1.00 104.58 ? 40  ARG   P CA  1 
ATOM   5852 C C   . ARG   B 2 22  ? 173.446 147.163 137.396 1.00 112.66 ? 40  ARG   P C   1 
ATOM   5853 O O   . ARG   B 2 22  ? 173.459 147.091 136.163 1.00 112.90 ? 40  ARG   P O   1 
ATOM   5854 C CB  . ARG   B 2 22  ? 173.498 149.130 138.994 1.00 103.00 ? 40  ARG   P CB  1 
ATOM   5855 C CG  . ARG   B 2 22  ? 172.402 149.930 138.256 1.00 101.24 ? 40  ARG   P CG  1 
ATOM   5856 C CD  . ARG   B 2 22  ? 172.764 151.395 138.085 1.00 97.88  ? 40  ARG   P CD  1 
ATOM   5857 N NE  . ARG   B 2 22  ? 172.916 152.096 139.356 1.00 99.48  ? 40  ARG   P NE  1 
ATOM   5858 C CZ  . ARG   B 2 22  ? 173.306 153.358 139.486 1.00 96.31  ? 40  ARG   P CZ  1 
ATOM   5859 N NH1 . ARG   B 2 22  ? 173.602 154.108 138.435 1.00 89.06  ? 40  ARG   P NH1 1 
ATOM   5860 N NH2 . ARG   B 2 22  ? 173.406 153.882 140.704 1.00 93.87  ? 40  ARG   P NH2 1 
ATOM   5861 N N   . LYS   B 2 23  ? 172.673 146.396 138.158 1.00 119.79 ? 41  LYS   P N   1 
ATOM   5862 C CA  . LYS   B 2 23  ? 171.710 145.471 137.584 1.00 120.99 ? 41  LYS   P CA  1 
ATOM   5863 C C   . LYS   B 2 23  ? 170.448 146.233 137.184 1.00 123.83 ? 41  LYS   P C   1 
ATOM   5864 O O   . LYS   B 2 23  ? 170.334 147.446 137.382 1.00 121.52 ? 41  LYS   P O   1 
ATOM   5865 C CB  . LYS   B 2 23  ? 171.388 144.353 138.574 1.00 119.88 ? 41  LYS   P CB  1 
ATOM   5866 C CG  . LYS   B 2 23  ? 172.605 143.611 139.127 1.00 118.32 ? 41  LYS   P CG  1 
ATOM   5867 C CD  . LYS   B 2 23  ? 173.396 142.906 138.033 1.00 117.67 ? 41  LYS   P CD  1 
ATOM   5868 C CE  . LYS   B 2 23  ? 174.548 142.097 138.613 1.00 117.03 ? 41  LYS   P CE  1 
ATOM   5869 N NZ  . LYS   B 2 23  ? 175.550 142.956 139.303 1.00 116.99 ? 41  LYS   P NZ  1 
ATOM   5870 N N   . ARG   B 2 24  ? 169.486 145.508 136.616 1.00 129.22 ? 42  ARG   P N   1 
ATOM   5871 C CA  . ARG   B 2 24  ? 168.221 146.071 136.161 1.00 132.30 ? 42  ARG   P CA  1 
ATOM   5872 C C   . ARG   B 2 24  ? 167.095 145.526 137.026 1.00 131.57 ? 42  ARG   P C   1 
ATOM   5873 O O   . ARG   B 2 24  ? 167.027 144.317 137.276 1.00 130.21 ? 42  ARG   P O   1 
ATOM   5874 C CB  . ARG   B 2 24  ? 167.972 145.738 134.685 1.00 133.65 ? 42  ARG   P CB  1 
ATOM   5875 C CG  . ARG   B 2 24  ? 167.038 146.709 133.951 1.00 134.84 ? 42  ARG   P CG  1 
ATOM   5876 C CD  . ARG   B 2 24  ? 165.569 146.312 134.060 1.00 135.82 ? 42  ARG   P CD  1 
ATOM   5877 N NE  . ARG   B 2 24  ? 164.680 147.375 133.599 1.00 136.65 ? 42  ARG   P NE  1 
ATOM   5878 C CZ  . ARG   B 2 24  ? 164.345 147.602 132.334 1.00 137.34 ? 42  ARG   P CZ  1 
ATOM   5879 N NH1 . ARG   B 2 24  ? 164.817 146.862 131.342 1.00 137.61 ? 42  ARG   P NH1 1 
ATOM   5880 N NH2 . ARG   B 2 24  ? 163.514 148.602 132.055 1.00 136.47 ? 42  ARG   P NH2 1 
ATOM   5881 N N   . ALA   B 2 25  ? 166.220 146.421 137.481 1.00 131.37 ? 43  ALA   P N   1 
ATOM   5882 C CA  . ALA   B 2 25  ? 165.031 146.063 138.245 1.00 128.52 ? 43  ALA   P CA  1 
ATOM   5883 C C   . ALA   B 2 25  ? 163.833 146.723 137.584 1.00 129.38 ? 43  ALA   P C   1 
ATOM   5884 O O   . ALA   B 2 25  ? 163.776 147.954 137.488 1.00 129.46 ? 43  ALA   P O   1 
ATOM   5885 C CB  . ALA   B 2 25  ? 165.155 146.502 139.707 1.00 125.43 ? 43  ALA   P CB  1 
ATOM   5886 N N   . ASN   B 2 26  ? 162.885 145.905 137.121 1.00 130.64 ? 44  ASN   P N   1 
ATOM   5887 C CA  . ASN   B 2 26  ? 161.716 146.443 136.431 1.00 129.73 ? 44  ASN   P CA  1 
ATOM   5888 C C   . ASN   B 2 26  ? 160.892 147.338 137.351 1.00 128.01 ? 44  ASN   P C   1 
ATOM   5889 O O   . ASN   B 2 26  ? 160.449 148.418 136.942 1.00 126.52 ? 44  ASN   P O   1 
ATOM   5890 C CB  . ASN   B 2 26  ? 160.858 145.304 135.869 1.00 126.54 ? 44  ASN   P CB  1 
ATOM   5891 C CG  . ASN   B 2 26  ? 160.499 144.255 136.913 1.00 122.43 ? 44  ASN   P CG  1 
ATOM   5892 O OD1 . ASN   B 2 26  ? 160.475 144.530 138.113 1.00 121.04 ? 44  ASN   P OD1 1 
ATOM   5893 N ND2 . ASN   B 2 26  ? 160.225 143.039 136.453 1.00 119.74 ? 44  ASN   P ND2 1 
ATOM   5894 N N   . SER   B 2 27  ? 160.691 146.912 138.599 1.00 125.57 ? 45  SER   P N   1 
ATOM   5895 C CA  . SER   B 2 27  ? 159.962 147.688 139.601 1.00 123.51 ? 45  SER   P CA  1 
ATOM   5896 C C   . SER   B 2 27  ? 158.545 148.014 139.121 1.00 120.60 ? 45  SER   P C   1 
ATOM   5897 O O   . SER   B 2 27  ? 158.162 149.175 138.959 1.00 119.87 ? 45  SER   P O   1 
ATOM   5898 C CB  . SER   B 2 27  ? 160.730 148.964 139.962 1.00 124.17 ? 45  SER   P CB  1 
ATOM   5899 O OG  . SER   B 2 27  ? 162.030 148.659 140.433 1.00 125.62 ? 45  SER   P OG  1 
ATOM   5900 N N   . PHE   B 2 28  ? 157.766 146.955 138.894 1.00 115.98 ? 46  PHE   P N   1 
ATOM   5901 C CA  . PHE   B 2 28  ? 156.383 147.114 138.460 1.00 109.74 ? 46  PHE   P CA  1 
ATOM   5902 C C   . PHE   B 2 28  ? 155.477 147.695 139.539 1.00 105.60 ? 46  PHE   P C   1 
ATOM   5903 O O   . PHE   B 2 28  ? 154.340 148.063 139.226 1.00 105.08 ? 46  PHE   P O   1 
ATOM   5904 C CB  . PHE   B 2 28  ? 155.819 145.770 138.004 1.00 108.06 ? 46  PHE   P CB  1 
ATOM   5905 C CG  . PHE   B 2 28  ? 156.194 145.401 136.599 1.00 109.78 ? 46  PHE   P CG  1 
ATOM   5906 C CD1 . PHE   B 2 28  ? 155.524 145.956 135.523 1.00 108.80 ? 46  PHE   P CD1 1 
ATOM   5907 C CD2 . PHE   B 2 28  ? 157.209 144.495 136.353 1.00 112.52 ? 46  PHE   P CD2 1 
ATOM   5908 C CE1 . PHE   B 2 28  ? 155.864 145.620 134.229 1.00 108.54 ? 46  PHE   P CE1 1 
ATOM   5909 C CE2 . PHE   B 2 28  ? 157.554 144.153 135.060 1.00 112.20 ? 46  PHE   P CE2 1 
ATOM   5910 C CZ  . PHE   B 2 28  ? 156.880 144.716 133.996 1.00 109.75 ? 46  PHE   P CZ  1 
ATOM   5911 N N   . LEU   B 2 29  ? 155.937 147.779 140.788 1.00 105.65 ? 47  LEU   P N   1 
ATOM   5912 C CA  . LEU   B 2 29  ? 155.172 148.318 141.908 1.00 103.67 ? 47  LEU   P CA  1 
ATOM   5913 C C   . LEU   B 2 29  ? 153.921 147.506 142.214 1.00 100.45 ? 47  LEU   P C   1 
ATOM   5914 O O   . LEU   B 2 29  ? 152.996 148.018 142.851 1.00 101.33 ? 47  LEU   P O   1 
ATOM   5915 C CB  . LEU   B 2 29  ? 154.785 149.783 141.669 1.00 104.94 ? 47  LEU   P CB  1 
ATOM   5916 C CG  . LEU   B 2 29  ? 155.919 150.751 141.331 1.00 107.09 ? 47  LEU   P CG  1 
ATOM   5917 C CD1 . LEU   B 2 29  ? 155.361 152.144 141.095 1.00 106.32 ? 47  LEU   P CD1 1 
ATOM   5918 C CD2 . LEU   B 2 29  ? 156.968 150.770 142.433 1.00 108.68 ? 47  LEU   P CD2 1 
ATOM   5919 N N   . GLU   B 2 30  ? 153.876 146.245 141.778 1.00 97.82  ? 48  GLU   P N   1 
ATOM   5920 C CA  . GLU   B 2 30  ? 152.741 145.367 142.028 1.00 94.08  ? 48  GLU   P CA  1 
ATOM   5921 C C   . GLU   B 2 30  ? 153.164 143.975 142.475 1.00 98.46  ? 48  GLU   P C   1 
ATOM   5922 O O   . GLU   B 2 30  ? 152.293 143.163 142.799 1.00 103.60 ? 48  GLU   P O   1 
ATOM   5923 C CB  . GLU   B 2 30  ? 151.873 145.270 140.754 1.00 90.96  ? 48  GLU   P CB  1 
ATOM   5924 C CG  . GLU   B 2 30  ? 150.510 144.589 140.885 1.00 87.06  ? 48  GLU   P CG  1 
ATOM   5925 C CD  . GLU   B 2 30  ? 149.604 145.253 141.896 1.00 86.89  ? 48  GLU   P CD  1 
ATOM   5926 O OE1 . GLU   B 2 30  ? 149.825 146.442 142.200 1.00 89.41  ? 48  GLU   P OE1 1 
ATOM   5927 O OE2 . GLU   B 2 30  ? 148.671 144.587 142.388 1.00 86.59  ? 48  GLU   P OE2 1 
ATOM   5928 N N   . GLU   B 2 31  ? 154.460 143.688 142.556 1.00 100.74 ? 49  GLU   P N   1 
ATOM   5929 C CA  . GLU   B 2 31  ? 154.970 142.336 142.766 1.00 106.88 ? 49  GLU   P CA  1 
ATOM   5930 C C   . GLU   B 2 31  ? 155.437 142.201 144.213 1.00 118.80 ? 49  GLU   P C   1 
ATOM   5931 O O   . GLU   B 2 31  ? 156.606 142.427 144.525 1.00 123.06 ? 49  GLU   P O   1 
ATOM   5932 C CB  . GLU   B 2 31  ? 156.099 142.035 141.790 1.00 106.82 ? 49  GLU   P CB  1 
ATOM   5933 C CG  . GLU   B 2 31  ? 155.674 142.036 140.334 1.00 106.99 ? 49  GLU   P CG  1 
ATOM   5934 C CD  . GLU   B 2 31  ? 156.808 141.678 139.395 1.00 109.51 ? 49  GLU   P CD  1 
ATOM   5935 O OE1 . GLU   B 2 31  ? 157.913 141.369 139.887 1.00 110.83 ? 49  GLU   P OE1 1 
ATOM   5936 O OE2 . GLU   B 2 31  ? 156.596 141.707 138.165 1.00 111.14 ? 49  GLU   P OE2 1 
ATOM   5937 N N   . LEU   B 2 32  ? 154.510 141.812 145.087 1.00 126.88 ? 50  LEU   P N   1 
ATOM   5938 C CA  . LEU   B 2 32  ? 154.804 141.438 146.479 1.00 132.02 ? 50  LEU   P CA  1 
ATOM   5939 C C   . LEU   B 2 32  ? 155.432 142.652 147.164 1.00 137.42 ? 50  LEU   P C   1 
ATOM   5940 O O   . LEU   B 2 32  ? 154.915 143.767 146.986 1.00 135.85 ? 50  LEU   P O   1 
ATOM   5941 C CB  . LEU   B 2 32  ? 155.641 140.154 146.448 1.00 130.17 ? 50  LEU   P CB  1 
ATOM   5942 C CG  . LEU   B 2 32  ? 155.356 139.054 147.483 1.00 131.25 ? 50  LEU   P CG  1 
ATOM   5943 C CD1 . LEU   B 2 32  ? 155.574 139.526 148.916 1.00 135.57 ? 50  LEU   P CD1 1 
ATOM   5944 C CD2 . LEU   B 2 32  ? 153.947 138.484 147.314 1.00 128.93 ? 50  LEU   P CD2 1 
ATOM   5945 N N   . ARG   B 2 33  ? 156.512 142.497 147.937 1.00 142.37 ? 51  ARG   P N   1 
ATOM   5946 C CA  . ARG   B 2 33  ? 157.238 143.608 148.544 1.00 144.58 ? 51  ARG   P CA  1 
ATOM   5947 C C   . ARG   B 2 33  ? 158.631 143.775 147.943 1.00 147.28 ? 51  ARG   P C   1 
ATOM   5948 O O   . ARG   B 2 33  ? 159.533 144.293 148.609 1.00 150.73 ? 51  ARG   P O   1 
ATOM   5949 C CB  . ARG   B 2 33  ? 157.321 143.423 150.063 1.00 146.87 ? 51  ARG   P CB  1 
ATOM   5950 C CG  . ARG   B 2 33  ? 157.949 142.115 150.522 1.00 149.40 ? 51  ARG   P CG  1 
ATOM   5951 C CD  . ARG   B 2 33  ? 157.917 141.988 152.036 1.00 149.66 ? 51  ARG   P CD  1 
ATOM   5952 N NE  . ARG   B 2 33  ? 158.271 140.643 152.480 1.00 150.03 ? 51  ARG   P NE  1 
ATOM   5953 C CZ  . ARG   B 2 33  ? 157.452 139.598 152.474 1.00 149.41 ? 51  ARG   P CZ  1 
ATOM   5954 N NH1 . ARG   B 2 33  ? 156.202 139.692 152.043 1.00 148.24 ? 51  ARG   P NH1 1 
ATOM   5955 N NH2 . ARG   B 2 33  ? 157.899 138.424 152.909 1.00 148.08 ? 51  ARG   P NH2 1 
ATOM   5956 N N   . HIS   B 2 34  ? 158.821 143.340 146.695 1.00 144.95 ? 52  HIS   P N   1 
ATOM   5957 C CA  . HIS   B 2 34  ? 160.066 143.523 145.939 1.00 150.17 ? 52  HIS   P CA  1 
ATOM   5958 C C   . HIS   B 2 34  ? 161.178 142.766 146.657 1.00 157.98 ? 52  HIS   P C   1 
ATOM   5959 O O   . HIS   B 2 34  ? 160.994 141.569 146.941 1.00 158.80 ? 52  HIS   P O   1 
ATOM   5960 C CB  . HIS   B 2 34  ? 160.301 145.022 145.726 1.00 147.36 ? 52  HIS   P CB  1 
ATOM   5961 C CG  . HIS   B 2 34  ? 159.239 145.689 144.909 1.00 142.91 ? 52  HIS   P CG  1 
ATOM   5962 N ND1 . HIS   B 2 34  ? 159.343 145.849 143.544 1.00 138.98 ? 52  HIS   P ND1 1 
ATOM   5963 C CD2 . HIS   B 2 34  ? 158.053 146.237 145.262 1.00 138.85 ? 52  HIS   P CD2 1 
ATOM   5964 C CE1 . HIS   B 2 34  ? 158.266 146.467 143.092 1.00 130.13 ? 52  HIS   P CE1 1 
ATOM   5965 N NE2 . HIS   B 2 34  ? 157.467 146.713 144.114 1.00 131.26 ? 52  HIS   P NE2 1 
ATOM   5966 N N   . SER   B 2 35  ? 162.320 143.387 146.967 1.00 163.30 ? 53  SER   P N   1 
ATOM   5967 C CA  . SER   B 2 35  ? 163.440 142.654 147.547 1.00 166.52 ? 53  SER   P CA  1 
ATOM   5968 C C   . SER   B 2 35  ? 163.142 142.139 148.950 1.00 169.62 ? 53  SER   P C   1 
ATOM   5969 O O   . SER   B 2 35  ? 163.843 141.238 149.424 1.00 172.16 ? 53  SER   P O   1 
ATOM   5970 C CB  . SER   B 2 35  ? 164.684 143.542 147.574 1.00 166.75 ? 53  SER   P CB  1 
ATOM   5971 O OG  . SER   B 2 35  ? 164.583 144.535 148.579 1.00 168.34 ? 53  SER   P OG  1 
ATOM   5972 N N   . SER   B 2 36  ? 162.134 142.693 149.626 1.00 167.89 ? 54  SER   P N   1 
ATOM   5973 C CA  . SER   B 2 36  ? 161.699 142.205 150.930 1.00 168.35 ? 54  SER   P CA  1 
ATOM   5974 C C   . SER   B 2 36  ? 162.780 142.415 151.989 1.00 172.64 ? 54  SER   P C   1 
ATOM   5975 O O   . SER   B 2 36  ? 162.966 143.542 152.460 1.00 173.23 ? 54  SER   P O   1 
ATOM   5976 C CB  . SER   B 2 36  ? 161.285 140.730 150.838 1.00 165.37 ? 54  SER   P CB  1 
ATOM   5977 O OG  . SER   B 2 36  ? 162.413 139.879 150.719 1.00 169.48 ? 54  SER   P OG  1 
ATOM   5978 N N   . LEU   B 2 37  ? 163.499 141.354 152.377 1.00 174.70 ? 55  LEU   P N   1 
ATOM   5979 C CA  . LEU   B 2 37  ? 164.411 141.462 153.513 1.00 173.89 ? 55  LEU   P CA  1 
ATOM   5980 C C   . LEU   B 2 37  ? 165.591 142.377 153.212 1.00 174.05 ? 55  LEU   P C   1 
ATOM   5981 O O   . LEU   B 2 37  ? 166.116 143.028 154.124 1.00 172.65 ? 55  LEU   P O   1 
ATOM   5982 C CB  . LEU   B 2 37  ? 164.897 140.069 153.933 1.00 171.98 ? 55  LEU   P CB  1 
ATOM   5983 C CG  . LEU   B 2 37  ? 165.581 139.142 152.912 1.00 171.15 ? 55  LEU   P CG  1 
ATOM   5984 C CD1 . LEU   B 2 37  ? 167.034 139.535 152.619 1.00 169.92 ? 55  LEU   P CD1 1 
ATOM   5985 C CD2 . LEU   B 2 37  ? 165.505 137.693 153.388 1.00 169.79 ? 55  LEU   P CD2 1 
ATOM   5986 N N   . GLU   B 2 38  ? 166.030 142.435 151.953 1.00 175.13 ? 56  GLU   P N   1 
ATOM   5987 C CA  . GLU   B 2 38  ? 167.162 143.288 151.602 1.00 174.60 ? 56  GLU   P CA  1 
ATOM   5988 C C   . GLU   B 2 38  ? 166.832 144.758 151.837 1.00 174.30 ? 56  GLU   P C   1 
ATOM   5989 O O   . GLU   B 2 38  ? 167.572 145.470 152.527 1.00 172.66 ? 56  GLU   P O   1 
ATOM   5990 C CB  . GLU   B 2 38  ? 167.562 143.045 150.144 1.00 173.59 ? 56  GLU   P CB  1 
ATOM   5991 C CG  . GLU   B 2 38  ? 168.775 143.839 149.654 1.00 172.67 ? 56  GLU   P CG  1 
ATOM   5992 C CD  . GLU   B 2 38  ? 170.043 143.521 150.424 1.00 171.64 ? 56  GLU   P CD  1 
ATOM   5993 O OE1 . GLU   B 2 38  ? 170.102 142.452 151.066 1.00 171.47 ? 56  GLU   P OE1 1 
ATOM   5994 O OE2 . GLU   B 2 38  ? 170.983 144.344 150.386 1.00 169.92 ? 56  GLU   P OE2 1 
ATOM   5995 N N   . ARG   B 2 39  ? 165.720 145.227 151.279 1.00 174.20 ? 57  ARG   P N   1 
ATOM   5996 C CA  . ARG   B 2 39  ? 165.325 146.626 151.405 1.00 172.06 ? 57  ARG   P CA  1 
ATOM   5997 C C   . ARG   B 2 39  ? 163.913 146.838 150.870 1.00 168.53 ? 57  ARG   P C   1 
ATOM   5998 O O   . ARG   B 2 39  ? 163.672 146.734 149.668 1.00 166.20 ? 57  ARG   P O   1 
ATOM   5999 C CB  . ARG   B 2 39  ? 166.311 147.533 150.661 1.00 170.23 ? 57  ARG   P CB  1 
ATOM   6000 C CG  . ARG   B 2 39  ? 165.946 149.007 150.689 1.00 168.52 ? 57  ARG   P CG  1 
ATOM   6001 C CD  . ARG   B 2 39  ? 167.181 149.879 150.524 1.00 166.49 ? 57  ARG   P CD  1 
ATOM   6002 N NE  . ARG   B 2 39  ? 166.845 151.295 150.406 1.00 165.95 ? 57  ARG   P NE  1 
ATOM   6003 C CZ  . ARG   B 2 39  ? 166.555 151.925 149.273 1.00 165.23 ? 57  ARG   P CZ  1 
ATOM   6004 N NH1 . ARG   B 2 39  ? 166.537 151.296 148.107 1.00 165.13 ? 57  ARG   P NH1 1 
ATOM   6005 N NH2 . ARG   B 2 39  ? 166.272 153.224 149.310 1.00 163.70 ? 57  ARG   P NH2 1 
HETATM 6006 C C1  . NAG   C 3 .   ? 182.109 177.787 131.182 1.00 61.48  ? 1   NAG   B C1  1 
HETATM 6007 C C2  . NAG   C 3 .   ? 182.407 178.990 132.078 1.00 58.76  ? 1   NAG   B C2  1 
HETATM 6008 C C3  . NAG   C 3 .   ? 181.252 179.232 133.043 1.00 65.06  ? 1   NAG   B C3  1 
HETATM 6009 C C4  . NAG   C 3 .   ? 179.945 179.333 132.272 1.00 65.69  ? 1   NAG   B C4  1 
HETATM 6010 C C5  . NAG   C 3 .   ? 179.777 178.051 131.463 1.00 62.68  ? 1   NAG   B C5  1 
HETATM 6011 C C6  . NAG   C 3 .   ? 178.485 177.997 130.682 1.00 65.60  ? 1   NAG   B C6  1 
HETATM 6012 C C7  . NAG   C 3 .   ? 184.791 179.414 132.563 1.00 62.02  ? 1   NAG   B C7  1 
HETATM 6013 C C8  . NAG   C 3 .   ? 185.932 179.025 133.472 1.00 63.25  ? 1   NAG   B C8  1 
HETATM 6014 N N2  . NAG   C 3 .   ? 183.627 178.786 132.808 1.00 57.58  ? 1   NAG   B N2  1 
HETATM 6015 O O3  . NAG   C 3 .   ? 181.530 180.398 133.769 1.00 74.72  ? 1   NAG   B O3  1 
HETATM 6016 O O4  . NAG   C 3 .   ? 178.901 179.517 133.201 1.00 72.38  ? 1   NAG   B O4  1 
HETATM 6017 O O5  . NAG   C 3 .   ? 180.858 177.941 130.561 1.00 62.79  ? 1   NAG   B O5  1 
HETATM 6018 O O6  . NAG   C 3 .   ? 177.568 178.920 131.218 1.00 69.15  ? 1   NAG   B O6  1 
HETATM 6019 O O7  . NAG   C 3 .   ? 184.945 180.239 131.677 1.00 63.66  ? 1   NAG   B O7  1 
HETATM 6020 C C1  . NAG   C 3 .   ? 178.022 180.552 133.684 1.00 74.79  ? 2   NAG   B C1  1 
HETATM 6021 C C2  . NAG   C 3 .   ? 176.752 180.364 134.517 1.00 73.24  ? 2   NAG   B C2  1 
HETATM 6022 C C3  . NAG   C 3 .   ? 176.440 181.649 135.272 1.00 78.66  ? 2   NAG   B C3  1 
HETATM 6023 C C4  . NAG   C 3 .   ? 177.650 182.066 136.095 1.00 82.45  ? 2   NAG   B C4  1 
HETATM 6024 C C5  . NAG   C 3 .   ? 178.879 182.167 135.185 1.00 81.48  ? 2   NAG   B C5  1 
HETATM 6025 C C6  . NAG   C 3 .   ? 180.147 182.516 135.930 1.00 77.63  ? 2   NAG   B C6  1 
HETATM 6026 C C7  . NAG   C 3 .   ? 174.713 179.067 134.036 1.00 73.95  ? 2   NAG   B C7  1 
HETATM 6027 C C8  . NAG   C 3 .   ? 173.637 178.825 133.005 1.00 69.69  ? 2   NAG   B C8  1 
HETATM 6028 N N2  . NAG   C 3 .   ? 175.640 179.980 133.691 1.00 72.34  ? 2   NAG   B N2  1 
HETATM 6029 O O3  . NAG   C 3 .   ? 175.314 181.412 136.073 1.00 79.23  ? 2   NAG   B O3  1 
HETATM 6030 O O4  . NAG   C 3 .   ? 177.340 183.302 136.696 1.00 79.70  ? 2   NAG   B O4  1 
HETATM 6031 O O5  . NAG   C 3 .   ? 179.083 180.934 134.522 1.00 83.83  ? 2   NAG   B O5  1 
HETATM 6032 O O6  . NAG   C 3 .   ? 180.411 181.524 136.894 1.00 76.51  ? 2   NAG   B O6  1 
HETATM 6033 O O7  . NAG   C 3 .   ? 174.719 178.468 135.100 1.00 75.08  ? 2   NAG   B O7  1 
HETATM 6034 C C1  . NAG   D 3 .   ? 186.155 153.955 123.318 1.00 80.05  ? 1   NAG   C C1  1 
HETATM 6035 C C2  . NAG   D 3 .   ? 186.827 152.706 122.766 1.00 77.49  ? 1   NAG   C C2  1 
HETATM 6036 C C3  . NAG   D 3 .   ? 185.788 151.720 122.239 1.00 78.35  ? 1   NAG   C C3  1 
HETATM 6037 C C4  . NAG   D 3 .   ? 184.809 152.394 121.286 1.00 79.64  ? 1   NAG   C C4  1 
HETATM 6038 C C5  . NAG   D 3 .   ? 184.275 153.710 121.850 1.00 82.62  ? 1   NAG   C C5  1 
HETATM 6039 C C6  . NAG   D 3 .   ? 183.333 153.515 123.016 1.00 83.20  ? 1   NAG   C C6  1 
HETATM 6040 C C7  . NAG   D 3 .   ? 189.075 153.280 121.971 1.00 77.48  ? 1   NAG   C C7  1 
HETATM 6041 C C8  . NAG   D 3 .   ? 189.920 153.621 120.780 1.00 80.09  ? 1   NAG   C C8  1 
HETATM 6042 N N2  . NAG   D 3 .   ? 187.782 153.048 121.726 1.00 73.84  ? 1   NAG   C N2  1 
HETATM 6043 O O3  . NAG   D 3 .   ? 185.083 151.140 123.332 1.00 78.33  ? 1   NAG   C O3  1 
HETATM 6044 O O4  . NAG   D 3 .   ? 185.441 152.641 120.035 1.00 85.99  ? 1   NAG   C O4  1 
HETATM 6045 O O5  . NAG   D 3 .   ? 185.346 154.542 122.319 1.00 83.98  ? 1   NAG   C O5  1 
HETATM 6046 O O6  . NAG   D 3 .   ? 183.234 154.692 123.807 1.00 84.56  ? 1   NAG   C O6  1 
HETATM 6047 O O7  . NAG   D 3 .   ? 189.544 153.218 123.103 1.00 77.53  ? 1   NAG   C O7  1 
HETATM 6048 C C1  . NAG   D 3 .   ? 184.848 152.079 119.194 1.00 34.66  ? 2   NAG   C C1  1 
HETATM 6049 C C2  . NAG   D 3 .   ? 183.668 152.043 118.227 1.00 34.66  ? 2   NAG   C C2  1 
HETATM 6050 C C3  . NAG   D 3 .   ? 183.694 150.756 117.408 1.00 34.66  ? 2   NAG   C C3  1 
HETATM 6051 C C4  . NAG   D 3 .   ? 185.048 150.577 116.736 1.00 34.66  ? 2   NAG   C C4  1 
HETATM 6052 C C5  . NAG   D 3 .   ? 186.167 150.679 117.767 1.00 34.66  ? 2   NAG   C C5  1 
HETATM 6053 C C6  . NAG   D 3 .   ? 187.545 150.634 117.149 1.00 34.66  ? 2   NAG   C C6  1 
HETATM 6054 C C7  . NAG   D 3 .   ? 181.494 153.099 118.646 1.00 34.66  ? 2   NAG   C C7  1 
HETATM 6055 C C8  . NAG   D 3 .   ? 181.843 154.032 117.527 1.00 34.66  ? 2   NAG   C C8  1 
HETATM 6056 N N2  . NAG   D 3 .   ? 182.407 152.168 118.938 1.00 34.66  ? 2   NAG   C N2  1 
HETATM 6057 O O3  . NAG   D 3 .   ? 182.668 150.804 116.423 1.00 34.66  ? 2   NAG   C O3  1 
HETATM 6058 O O4  . NAG   D 3 .   ? 185.111 149.304 116.103 1.00 34.66  ? 2   NAG   C O4  1 
HETATM 6059 O O5  . NAG   D 3 .   ? 186.068 151.927 118.470 1.00 34.66  ? 2   NAG   C O5  1 
HETATM 6060 O O6  . NAG   D 3 .   ? 187.557 149.851 115.964 1.00 34.66  ? 2   NAG   C O6  1 
HETATM 6061 O O7  . NAG   D 3 .   ? 180.436 153.186 119.260 1.00 34.66  ? 2   NAG   C O7  1 
HETATM 6062 C C1  . NAG   E 3 .   ? 184.081 148.955 136.767 1.00 71.06  ? 1   NAG   D C1  1 
HETATM 6063 C C2  . NAG   E 3 .   ? 183.022 148.971 137.869 1.00 72.46  ? 1   NAG   D C2  1 
HETATM 6064 C C3  . NAG   E 3 .   ? 183.645 148.468 139.166 1.00 77.88  ? 1   NAG   D C3  1 
HETATM 6065 C C4  . NAG   E 3 .   ? 184.237 147.087 138.936 1.00 78.20  ? 1   NAG   D C4  1 
HETATM 6066 C C5  . NAG   E 3 .   ? 185.223 147.150 137.770 1.00 75.36  ? 1   NAG   D C5  1 
HETATM 6067 C C6  . NAG   E 3 .   ? 185.830 145.805 137.446 1.00 78.60  ? 1   NAG   D C6  1 
HETATM 6068 C C7  . NAG   E 3 .   ? 183.138 151.396 138.318 1.00 73.19  ? 1   NAG   D C7  1 
HETATM 6069 C C8  . NAG   E 3 .   ? 182.308 152.649 138.451 1.00 69.08  ? 1   NAG   D C8  1 
HETATM 6070 N N2  . NAG   E 3 .   ? 182.446 150.278 138.039 1.00 71.15  ? 1   NAG   D N2  1 
HETATM 6071 O O3  . NAG   E 3 .   ? 182.651 148.458 140.153 1.00 85.32  ? 1   NAG   D O3  1 
HETATM 6072 O O4  . NAG   E 3 .   ? 184.879 146.687 140.122 1.00 86.78  ? 1   NAG   D O4  1 
HETATM 6073 O O5  . NAG   E 3 .   ? 184.573 147.648 136.617 1.00 75.46  ? 1   NAG   D O5  1 
HETATM 6074 O O6  . NAG   E 3 .   ? 186.418 145.261 138.603 1.00 80.92  ? 1   NAG   D O6  1 
HETATM 6075 O O7  . NAG   E 3 .   ? 184.350 151.420 138.466 1.00 76.52  ? 1   NAG   D O7  1 
HETATM 6076 C C1  . NAG   E 3 .   ? 185.197 146.040 141.369 1.00 100.72 ? 2   NAG   D C1  1 
HETATM 6077 C C2  . NAG   E 3 .   ? 186.387 145.465 142.140 1.00 103.78 ? 2   NAG   D C2  1 
HETATM 6078 C C3  . NAG   E 3 .   ? 185.946 145.103 143.553 1.00 108.42 ? 2   NAG   D C3  1 
HETATM 6079 C C4  . NAG   E 3 .   ? 185.293 146.309 144.216 1.00 110.15 ? 2   NAG   D C4  1 
HETATM 6080 C C5  . NAG   E 3 .   ? 184.148 146.808 143.332 1.00 109.64 ? 2   NAG   D C5  1 
HETATM 6081 C C6  . NAG   E 3 .   ? 183.423 148.010 143.893 1.00 111.30 ? 2   NAG   D C6  1 
HETATM 6082 C C7  . NAG   E 3 .   ? 188.127 144.066 140.918 1.00 102.75 ? 2   NAG   D C7  1 
HETATM 6083 C C8  . NAG   E 3 .   ? 189.192 145.138 140.973 1.00 97.59  ? 2   NAG   D C8  1 
HETATM 6084 N N2  . NAG   E 3 .   ? 186.906 144.296 141.465 1.00 103.29 ? 2   NAG   D N2  1 
HETATM 6085 O O3  . NAG   E 3 .   ? 187.072 144.657 144.261 1.00 112.00 ? 2   NAG   D O3  1 
HETATM 6086 O O4  . NAG   E 3 .   ? 184.833 145.894 145.481 1.00 112.71 ? 2   NAG   D O4  1 
HETATM 6087 O O5  . NAG   E 3 .   ? 184.660 147.142 142.058 1.00 106.44 ? 2   NAG   D O5  1 
HETATM 6088 O O6  . NAG   E 3 .   ? 182.396 148.399 143.011 1.00 113.04 ? 2   NAG   D O6  1 
HETATM 6089 O O7  . NAG   E 3 .   ? 188.385 142.999 140.381 1.00 101.81 ? 2   NAG   D O7  1 
HETATM 6090 C C11 . A1AVC F 4 .   ? 146.642 142.240 135.493 1.00 73.61  ? 801 A1AVC A C11 1 
HETATM 6091 C C12 . A1AVC F 4 .   ? 147.762 142.888 134.629 1.00 71.76  ? 801 A1AVC A C12 1 
HETATM 6092 C C13 . A1AVC F 4 .   ? 147.709 142.187 133.239 1.00 71.49  ? 801 A1AVC A C13 1 
HETATM 6093 C C14 . A1AVC F 4 .   ? 148.769 141.567 132.629 1.00 71.77  ? 801 A1AVC A C14 1 
HETATM 6094 C C15 . A1AVC F 4 .   ? 150.173 141.500 133.259 1.00 71.56  ? 801 A1AVC A C15 1 
HETATM 6095 C C16 . A1AVC F 4 .   ? 148.554 140.908 131.226 1.00 69.08  ? 801 A1AVC A C16 1 
HETATM 6096 C C01 . A1AVC F 4 .   ? 148.333 140.877 136.911 1.00 72.89  ? 801 A1AVC A C01 1 
HETATM 6097 C C02 . A1AVC F 4 .   ? 146.882 141.323 136.532 1.00 74.86  ? 801 A1AVC A C02 1 
HETATM 6098 C C03 . A1AVC F 4 .   ? 145.781 140.790 137.247 1.00 69.19  ? 801 A1AVC A C03 1 
HETATM 6099 C C04 . A1AVC F 4 .   ? 144.433 141.183 136.913 1.00 72.43  ? 801 A1AVC A C04 1 
HETATM 6100 C C05 . A1AVC F 4 .   ? 143.329 140.637 137.646 1.00 69.47  ? 801 A1AVC A C05 1 
HETATM 6101 C C06 . A1AVC F 4 .   ? 142.017 141.019 137.323 1.00 69.19  ? 801 A1AVC A C06 1 
HETATM 6102 C C07 . A1AVC F 4 .   ? 141.783 141.931 136.288 1.00 68.38  ? 801 A1AVC A C07 1 
HETATM 6103 C C08 . A1AVC F 4 .   ? 142.860 142.464 135.572 1.00 70.48  ? 801 A1AVC A C08 1 
HETATM 6104 C C09 . A1AVC F 4 .   ? 144.205 142.070 135.906 1.00 74.76  ? 801 A1AVC A C09 1 
HETATM 6105 C C10 . A1AVC F 4 .   ? 145.306 142.614 135.177 1.00 72.29  ? 801 A1AVC A C10 1 
HETATM 6106 C C17 . A1AVC F 4 .   ? 148.814 139.344 131.278 1.00 72.58  ? 801 A1AVC A C17 1 
HETATM 6107 C C18 . A1AVC F 4 .   ? 149.773 138.798 130.154 1.00 72.19  ? 801 A1AVC A C18 1 
HETATM 6108 C C19 . A1AVC F 4 .   ? 149.081 138.080 128.994 1.00 73.23  ? 801 A1AVC A C19 1 
HETATM 6109 C C20 . A1AVC F 4 .   ? 147.971 138.955 128.386 1.00 70.15  ? 801 A1AVC A C20 1 
HETATM 6110 C C21 . A1AVC F 4 .   ? 148.512 136.707 129.433 1.00 73.94  ? 801 A1AVC A C21 1 
HETATM 6111 C C22 . A1AVC F 4 .   ? 148.316 135.779 128.189 1.00 75.88  ? 801 A1AVC A C22 1 
HETATM 6112 C C23 . A1AVC F 4 .   ? 147.072 134.865 128.240 1.00 78.94  ? 801 A1AVC A C23 1 
HETATM 6113 C C24 . A1AVC F 4 .   ? 145.901 135.274 127.297 1.00 83.08  ? 801 A1AVC A C24 1 
HETATM 6114 C C25 . A1AVC F 4 .   ? 144.715 134.354 127.560 1.00 76.79  ? 801 A1AVC A C25 1 
HETATM 6115 C C26 . A1AVC F 4 .   ? 146.307 135.157 125.826 1.00 81.81  ? 801 A1AVC A C26 1 
HETATM 6116 C C27 . A1AVC F 4 .   ? 145.128 135.179 124.809 1.00 82.64  ? 801 A1AVC A C27 1 
HETATM 6117 C C28 . A1AVC F 4 .   ? 145.636 135.562 123.392 1.00 82.60  ? 801 A1AVC A C28 1 
HETATM 6118 C C29 . A1AVC F 4 .   ? 144.882 134.871 122.252 1.00 86.48  ? 801 A1AVC A C29 1 
HETATM 6119 C C30 . A1AVC F 4 .   ? 145.185 133.348 122.191 1.00 82.74  ? 801 A1AVC A C30 1 
HETATM 6120 C C31 . A1AVC F 4 .   ? 145.206 135.526 120.929 1.00 80.69  ? 801 A1AVC A C31 1 
HETATM 6121 O O32 . A1AVC F 4 .   ? 145.062 143.525 134.143 1.00 69.13  ? 801 A1AVC A O32 1 
HETATM 6122 O O33 . A1AVC F 4 .   ? 145.969 139.876 138.287 1.00 65.35  ? 801 A1AVC A O33 1 
HETATM 6123 C C22 . 6PL   G 5 .   ? 124.746 144.459 129.679 0.60 49.94  ? 802 6PL   A C22 1 
HETATM 6124 C C21 . 6PL   G 5 .   ? 125.924 145.385 129.960 0.60 52.59  ? 802 6PL   A C21 1 
HETATM 6125 C C20 . 6PL   G 5 .   ? 126.945 144.790 130.923 0.60 53.45  ? 802 6PL   A C20 1 
HETATM 6126 C C19 . 6PL   G 5 .   ? 126.370 144.484 132.300 0.60 52.60  ? 802 6PL   A C19 1 
HETATM 6127 C C18 . 6PL   G 5 .   ? 127.436 144.210 133.354 0.60 51.93  ? 802 6PL   A C18 1 
HETATM 6128 C C17 . 6PL   G 5 .   ? 126.847 143.839 134.710 0.60 51.42  ? 802 6PL   A C17 1 
HETATM 6129 C C16 . 6PL   G 5 .   ? 127.822 144.009 135.868 0.60 52.06  ? 802 6PL   A C16 1 
HETATM 6130 C C15 . 6PL   G 5 .   ? 127.313 143.421 137.178 0.60 51.61  ? 802 6PL   A C15 1 
HETATM 6131 C C14 . 6PL   G 5 .   ? 126.204 144.238 137.831 0.60 50.79  ? 802 6PL   A C14 1 
HETATM 6132 C C13 . 6PL   G 5 .   ? 125.318 143.421 138.762 0.60 45.59  ? 802 6PL   A C13 1 
HETATM 6133 C C12 . 6PL   G 5 .   ? 124.313 142.570 138.007 0.60 44.81  ? 802 6PL   A C12 1 
HETATM 6134 C C11 . 6PL   G 5 .   ? 123.571 141.608 138.884 0.60 45.30  ? 802 6PL   A C11 1 
HETATM 6135 O O11 . 6PL   G 5 .   ? 123.555 141.646 140.089 0.60 47.47  ? 802 6PL   A O11 1 
HETATM 6136 O O3  . 6PL   G 5 .   ? 122.928 140.679 138.186 0.60 45.19  ? 802 6PL   A O3  1 
HETATM 6137 C C3  . 6PL   G 5 .   ? 121.563 140.889 137.841 0.60 41.78  ? 802 6PL   A C3  1 
HETATM 6138 C C2  . 6PL   G 5 .   ? 120.673 140.509 139.019 0.60 40.22  ? 802 6PL   A C2  1 
HETATM 6139 C C1  . 6PL   G 5 .   ? 120.040 139.133 138.881 0.60 40.24  ? 802 6PL   A C1  1 
HETATM 6140 O O3P . 6PL   G 5 .   ? 120.936 138.151 138.419 0.60 39.37  ? 802 6PL   A O3P 1 
HETATM 6141 P P   . 6PL   G 5 .   ? 120.407 136.612 138.378 0.60 35.19  ? 802 6PL   A P   1 
HETATM 6142 O O1P . 6PL   G 5 .   ? 121.314 135.698 139.143 0.60 38.03  ? 802 6PL   A O1P 1 
HETATM 6143 O O2P . 6PL   G 5 .   ? 118.940 136.579 138.661 0.60 36.88  ? 802 6PL   A O2P 1 
HETATM 6144 O O4P . 6PL   G 5 .   ? 120.689 136.370 136.777 0.60 43.64  ? 802 6PL   A O4P 1 
HETATM 6145 C C4  . 6PL   G 5 .   ? 120.261 137.269 135.784 0.60 46.36  ? 802 6PL   A C4  1 
HETATM 6146 C C5  . 6PL   G 5 .   ? 121.225 137.267 134.621 0.60 46.57  ? 802 6PL   A C5  1 
HETATM 6147 N N   . 6PL   G 5 .   ? 121.758 135.942 134.132 0.60 46.46  ? 802 6PL   A N   1 
HETATM 6148 C C7  . 6PL   G 5 .   ? 120.699 134.896 134.113 0.60 46.01  ? 802 6PL   A C7  1 
HETATM 6149 C C8  . 6PL   G 5 .   ? 122.228 136.166 132.737 0.60 49.66  ? 802 6PL   A C8  1 
HETATM 6150 C C6  . 6PL   G 5 .   ? 122.938 135.445 134.899 0.60 46.25  ? 802 6PL   A C6  1 
HETATM 6151 O O2  . 6PL   G 5 .   ? 119.607 141.427 139.346 0.60 42.99  ? 802 6PL   A O2  1 
HETATM 6152 C C31 . 6PL   G 5 .   ? 119.503 142.730 139.083 0.60 45.87  ? 802 6PL   A C31 1 
HETATM 6153 O O31 . 6PL   G 5 .   ? 118.615 143.170 138.400 0.60 49.78  ? 802 6PL   A O31 1 
HETATM 6154 C C32 . 6PL   G 5 .   ? 120.580 143.567 139.718 0.60 44.81  ? 802 6PL   A C32 1 
HETATM 6155 C C33 . 6PL   G 5 .   ? 120.075 144.522 140.786 0.60 45.72  ? 802 6PL   A C33 1 
HETATM 6156 C C34 . 6PL   G 5 .   ? 118.905 145.405 140.356 0.60 49.97  ? 802 6PL   A C34 1 
HETATM 6157 C C35 . 6PL   G 5 .   ? 119.135 146.185 139.064 0.60 52.40  ? 802 6PL   A C35 1 
HETATM 6158 C C36 . 6PL   G 5 .   ? 120.307 147.158 139.088 0.60 51.81  ? 802 6PL   A C36 1 
HETATM 6159 C C37 . 6PL   G 5 .   ? 120.092 148.322 140.048 0.60 53.53  ? 802 6PL   A C37 1 
HETATM 6160 C C38 . 6PL   G 5 .   ? 121.128 149.432 139.911 0.60 55.72  ? 802 6PL   A C38 1 
HETATM 6161 C C39 . 6PL   G 5 .   ? 122.530 148.984 140.308 0.60 54.61  ? 802 6PL   A C39 1 
HETATM 6162 C C40 . 6PL   G 5 .   ? 123.540 150.121 140.410 0.60 54.33  ? 802 6PL   A C40 1 
HETATM 6163 C C41 . 6PL   G 5 .   ? 124.217 150.458 139.086 0.60 54.62  ? 802 6PL   A C41 1 
HETATM 6164 C C42 . 6PL   G 5 .   ? 125.327 149.491 138.686 0.60 54.84  ? 802 6PL   A C42 1 
HETATM 6165 C C43 . 6PL   G 5 .   ? 126.241 150.042 137.596 0.60 56.64  ? 802 6PL   A C43 1 
HETATM 6166 C C44 . 6PL   G 5 .   ? 127.539 149.262 137.413 0.60 55.34  ? 802 6PL   A C44 1 
HETATM 6167 C C45 . 6PL   G 5 .   ? 127.344 147.847 136.877 0.60 55.07  ? 802 6PL   A C45 1 
HETATM 6168 C C46 . 6PL   G 5 .   ? 126.807 147.797 135.452 0.60 54.86  ? 802 6PL   A C46 1 
HETATM 6169 C C26 . 6PL   H 5 .   ? 158.874 114.150 155.479 0.60 83.63  ? 803 6PL   A C26 1 
HETATM 6170 C C25 . 6PL   H 5 .   ? 159.287 115.560 155.879 0.60 86.85  ? 803 6PL   A C25 1 
HETATM 6171 C C24 . 6PL   H 5 .   ? 158.435 116.642 155.225 0.60 87.31  ? 803 6PL   A C24 1 
HETATM 6172 C C23 . 6PL   H 5 .   ? 157.007 116.703 155.755 0.60 85.31  ? 803 6PL   A C23 1 
HETATM 6173 C C22 . 6PL   H 5 .   ? 156.169 117.793 155.097 0.60 83.73  ? 803 6PL   A C22 1 
HETATM 6174 C C21 . 6PL   H 5 .   ? 154.707 117.776 155.527 0.60 81.79  ? 803 6PL   A C21 1 
HETATM 6175 C C20 . 6PL   H 5 .   ? 153.830 118.740 154.736 0.60 80.25  ? 803 6PL   A C20 1 
HETATM 6176 C C19 . 6PL   H 5 .   ? 154.132 120.208 155.014 0.60 79.97  ? 803 6PL   A C19 1 
HETATM 6177 C C18 . 6PL   H 5 .   ? 153.143 121.161 154.353 0.60 79.75  ? 803 6PL   A C18 1 
HETATM 6178 C C17 . 6PL   H 5 .   ? 153.455 122.631 154.611 0.60 77.54  ? 803 6PL   A C17 1 
HETATM 6179 C C16 . 6PL   H 5 .   ? 152.561 123.586 153.831 0.60 77.11  ? 803 6PL   A C16 1 
HETATM 6180 C C15 . 6PL   H 5 .   ? 152.693 125.035 154.282 0.60 74.79  ? 803 6PL   A C15 1 
HETATM 6181 C C14 . 6PL   H 5 .   ? 151.769 125.988 153.534 0.60 72.98  ? 803 6PL   A C14 1 
HETATM 6182 C C13 . 6PL   H 5 .   ? 152.295 126.374 152.156 0.60 73.44  ? 803 6PL   A C13 1 
HETATM 6183 C C12 . 6PL   H 5 .   ? 151.397 127.392 151.474 0.60 71.31  ? 803 6PL   A C12 1 
HETATM 6184 C C11 . 6PL   H 5 .   ? 152.031 128.083 150.300 0.60 74.43  ? 803 6PL   A C11 1 
HETATM 6185 O O11 . 6PL   H 5 .   ? 153.157 127.898 149.910 0.60 73.73  ? 803 6PL   A O11 1 
HETATM 6186 O O3  . 6PL   H 5 .   ? 151.189 128.938 149.732 0.60 74.80  ? 803 6PL   A O3  1 
HETATM 6187 C C3  . 6PL   H 5 .   ? 151.703 130.040 148.990 0.60 73.11  ? 803 6PL   A C3  1 
HETATM 6188 C C2  . 6PL   H 5 .   ? 152.161 129.595 147.616 0.60 73.27  ? 803 6PL   A C2  1 
HETATM 6189 C C1  . 6PL   H 5 .   ? 152.395 130.707 146.598 0.60 71.99  ? 803 6PL   A C1  1 
HETATM 6190 O O3P . 6PL   H 5 .   ? 153.772 130.874 146.340 0.60 75.97  ? 803 6PL   A O3P 1 
HETATM 6191 P P   . 6PL   H 5 .   ? 154.415 132.369 146.209 0.60 80.07  ? 803 6PL   A P   1 
HETATM 6192 O O1P . 6PL   H 5 .   ? 153.351 133.428 146.165 0.60 75.17  ? 803 6PL   A O1P 1 
HETATM 6193 O O2P . 6PL   H 5 .   ? 155.566 132.520 147.154 0.60 71.79  ? 803 6PL   A O2P 1 
HETATM 6194 O O4P . 6PL   H 5 .   ? 154.967 132.123 144.673 0.60 75.28  ? 803 6PL   A O4P 1 
HETATM 6195 C C4  . 6PL   H 5 .   ? 156.335 131.884 144.453 0.60 71.02  ? 803 6PL   A C4  1 
HETATM 6196 C C5  . 6PL   H 5 .   ? 156.633 131.318 143.079 0.60 69.68  ? 803 6PL   A C5  1 
HETATM 6197 N N   . 6PL   H 5 .   ? 156.094 132.010 141.843 0.60 67.91  ? 803 6PL   A N   1 
HETATM 6198 C C7  . 6PL   H 5 .   ? 156.426 133.461 141.830 0.60 65.63  ? 803 6PL   A C7  1 
HETATM 6199 C C8  . 6PL   H 5 .   ? 156.763 131.380 140.667 0.60 67.66  ? 803 6PL   A C8  1 
HETATM 6200 C C6  . 6PL   H 5 .   ? 154.617 131.842 141.680 0.60 67.76  ? 803 6PL   A C6  1 
HETATM 6201 O O2  . 6PL   H 5 .   ? 151.227 128.613 147.146 0.60 72.99  ? 803 6PL   A O2  1 
HETATM 6202 C C31 . 6PL   H 5 .   ? 149.934 128.905 147.014 0.60 70.51  ? 803 6PL   A C31 1 
HETATM 6203 O O31 . 6PL   H 5 .   ? 149.513 129.980 146.665 0.60 69.96  ? 803 6PL   A O31 1 
HETATM 6204 C C32 . 6PL   H 5 .   ? 149.080 127.717 147.366 0.60 67.77  ? 803 6PL   A C32 1 
HETATM 6205 C C33 . 6PL   H 5 .   ? 147.590 127.957 147.188 0.60 65.37  ? 803 6PL   A C33 1 
HETATM 6206 C C34 . 6PL   H 5 .   ? 146.769 126.717 147.522 0.60 63.48  ? 803 6PL   A C34 1 
HETATM 6207 C C35 . 6PL   H 5 .   ? 145.343 126.794 146.994 0.60 60.79  ? 803 6PL   A C35 1 
HETATM 6208 C C36 . 6PL   H 5 .   ? 144.439 127.743 147.772 0.60 59.41  ? 803 6PL   A C36 1 
HETATM 6209 C C37 . 6PL   H 5 .   ? 142.986 127.670 147.316 0.60 58.14  ? 803 6PL   A C37 1 
HETATM 6210 C C38 . 6PL   H 5 .   ? 142.709 128.389 146.001 0.60 57.74  ? 803 6PL   A C38 1 
HETATM 6211 C C39 . 6PL   H 5 .   ? 141.482 127.850 145.278 0.60 55.89  ? 803 6PL   A C39 1 
HETATM 6212 C C40 . 6PL   H 5 .   ? 141.081 128.676 144.064 0.60 53.74  ? 803 6PL   A C40 1 
HETATM 6213 C C41 . 6PL   H 5 .   ? 140.287 127.884 143.032 0.60 53.45  ? 803 6PL   A C41 1 
HETATM 6214 C C42 . 6PL   H 5 .   ? 138.908 127.449 143.511 0.60 53.52  ? 803 6PL   A C42 1 
HETATM 6215 C C43 . 6PL   H 5 .   ? 138.052 126.864 142.394 0.60 52.73  ? 803 6PL   A C43 1 
HETATM 6216 C C44 . 6PL   H 5 .   ? 136.630 126.521 142.821 0.60 52.00  ? 803 6PL   A C44 1 
HETATM 6217 C C45 . 6PL   H 5 .   ? 136.559 125.336 143.777 0.60 52.34  ? 803 6PL   A C45 1 
HETATM 6218 C C46 . 6PL   H 5 .   ? 135.136 124.901 144.101 0.60 49.01  ? 803 6PL   A C46 1 
HETATM 6219 C C1  . NAG   I 6 .   ? 180.194 165.473 167.353 1.00 91.82  ? 804 NAG   A C1  1 
HETATM 6220 C C2  . NAG   I 6 .   ? 179.420 165.466 168.661 1.00 93.02  ? 804 NAG   A C2  1 
HETATM 6221 C C3  . NAG   I 6 .   ? 178.989 164.043 169.020 1.00 92.25  ? 804 NAG   A C3  1 
HETATM 6222 C C4  . NAG   I 6 .   ? 179.976 163.009 168.489 1.00 91.73  ? 804 NAG   A C4  1 
HETATM 6223 C C5  . NAG   I 6 .   ? 180.189 163.147 166.982 1.00 92.03  ? 804 NAG   A C5  1 
HETATM 6224 C C6  . NAG   I 6 .   ? 179.431 162.113 166.181 1.00 91.58  ? 804 NAG   A C6  1 
HETATM 6225 C C7  . NAG   I 6 .   ? 180.583 167.330 169.758 1.00 92.00  ? 804 NAG   A C7  1 
HETATM 6226 C C8  . NAG   I 6 .   ? 181.393 167.757 170.945 1.00 90.04  ? 804 NAG   A C8  1 
HETATM 6227 N N2  . NAG   I 6 .   ? 180.209 166.046 169.736 1.00 93.31  ? 804 NAG   A N2  1 
HETATM 6228 O O3  . NAG   I 6 .   ? 177.693 163.795 168.487 1.00 90.13  ? 804 NAG   A O3  1 
HETATM 6229 O O4  . NAG   I 6 .   ? 181.228 163.151 169.151 1.00 89.31  ? 804 NAG   A O4  1 
HETATM 6230 O O5  . NAG   I 6 .   ? 179.738 164.430 166.532 1.00 94.00  ? 804 NAG   A O5  1 
HETATM 6231 O O6  . NAG   I 6 .   ? 178.148 161.864 166.737 1.00 92.36  ? 804 NAG   A O6  1 
HETATM 6232 O O7  . NAG   I 6 .   ? 180.282 168.110 168.861 1.00 91.40  ? 804 NAG   A O7  1 
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