data_9BP0
# 
_entry.id   9BP0 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BP0         pdb_00009bp0 10.2210/pdb9bp0/pdb 
WWPDB D_1000283511 ?            ?                   
EMDB  EMD-44756    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-05-14 ? 
2 'EM metadata'     1 0 2025-05-14 ? 
3 'Half map'        1 0 2025-05-14 1 
4 'Half map'        1 0 2025-05-14 2 
5 Image             1 0 2025-05-14 ? 
6 'Primary map'     1 0 2025-05-14 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BP0 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-06 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure  of human  heteromeric Glycine Receptor alpha3S346E-beta with glycine' 
_pdbx_database_related.db_id          EMD-44756 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              weiwei.wang@utsouthwestern.edu 
_pdbx_contact_author.name_first         Weiwei 
_pdbx_contact_author.name_last          Wang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0215-9467 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Liu, X.'  1 0000-0003-3560-0850 
'Wang, W.' 2 0000-0002-0215-9467 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM structure  of human  heteromeric Glycine Receptor alpha3S346E-beta with glycine' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Liu, X.'  1 0000-0003-3560-0850 
primary 'Wang, W.' 2 0000-0002-0215-9467 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Glycine receptor subunit alpha-3'                        48978.555 4 ? ? ? ? 
2 polymer     man 'Glycine receptor subunit beta,Green fluorescent protein' 76584.531 1 ? ? ? ? 
3 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose                  221.208   5 ? ? ? ? 
4 non-polymer syn GLYCINE                                                   75.067    4 ? ? ? ? 
# 
_entity_name_com.entity_id   2 
_entity_name_com.name        'Glycine receptor 58 kDa subunit' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;ARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD
DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFG
YTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWV
SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRK
RKNKTEAFDMDDEVREERFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLI
FNIFYWVIYKILRHEDIHQQQD
;
;ARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD
DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFG
YTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWV
SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRK
RKNKTEAFDMDDEVREERFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLI
FNIFYWVIYKILRHEDIHQQQD
;
A,B,C,D ? 
2 'polypeptide(L)' no no 
;KSSKKGKGKKKQYLCPSQQSAEDLARVPANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVN
IFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCP
LDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRR
QVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASL
VEYAVVQVMLNGGSSAAAVSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVT
TFSYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLE
YNYNSHNVYIMADKQKNGIKVNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLLE
FVTAAGITHGMDELYKSGSGSGVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNK
KPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL
;
;KSSKKGKGKKKQYLCPSQQSAEDLARVPANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVN
IFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCP
LDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRR
QVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASL
VEYAVVQVMLNGGSSAAAVSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVT
TFSYGVQCFSRYPDHMKQHDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLE
YNYNSHNVYIMADKQKNGIKVNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLLE
FVTAAGITHGMDELYKSGSGSGVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNK
KPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL
;
E       ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 2-acetamido-2-deoxy-beta-D-glucopyranose NAG 
4 GLYCINE                                  GLY 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   ARG n 
1 3   SER n 
1 4   ARG n 
1 5   SER n 
1 6   ALA n 
1 7   PRO n 
1 8   MET n 
1 9   SER n 
1 10  PRO n 
1 11  SER n 
1 12  ASP n 
1 13  PHE n 
1 14  LEU n 
1 15  ASP n 
1 16  LYS n 
1 17  LEU n 
1 18  MET n 
1 19  GLY n 
1 20  ARG n 
1 21  THR n 
1 22  SER n 
1 23  GLY n 
1 24  TYR n 
1 25  ASP n 
1 26  ALA n 
1 27  ARG n 
1 28  ILE n 
1 29  ARG n 
1 30  PRO n 
1 31  ASN n 
1 32  PHE n 
1 33  LYS n 
1 34  GLY n 
1 35  PRO n 
1 36  PRO n 
1 37  VAL n 
1 38  ASN n 
1 39  VAL n 
1 40  THR n 
1 41  CYS n 
1 42  ASN n 
1 43  ILE n 
1 44  PHE n 
1 45  ILE n 
1 46  ASN n 
1 47  SER n 
1 48  PHE n 
1 49  GLY n 
1 50  SER n 
1 51  ILE n 
1 52  ALA n 
1 53  GLU n 
1 54  THR n 
1 55  THR n 
1 56  MET n 
1 57  ASP n 
1 58  TYR n 
1 59  ARG n 
1 60  VAL n 
1 61  ASN n 
1 62  ILE n 
1 63  PHE n 
1 64  LEU n 
1 65  ARG n 
1 66  GLN n 
1 67  LYS n 
1 68  TRP n 
1 69  ASN n 
1 70  ASP n 
1 71  PRO n 
1 72  ARG n 
1 73  LEU n 
1 74  ALA n 
1 75  TYR n 
1 76  SER n 
1 77  GLU n 
1 78  TYR n 
1 79  PRO n 
1 80  ASP n 
1 81  ASP n 
1 82  SER n 
1 83  LEU n 
1 84  ASP n 
1 85  LEU n 
1 86  ASP n 
1 87  PRO n 
1 88  SER n 
1 89  MET n 
1 90  LEU n 
1 91  ASP n 
1 92  SER n 
1 93  ILE n 
1 94  TRP n 
1 95  LYS n 
1 96  PRO n 
1 97  ASP n 
1 98  LEU n 
1 99  PHE n 
1 100 PHE n 
1 101 ALA n 
1 102 ASN n 
1 103 GLU n 
1 104 LYS n 
1 105 GLY n 
1 106 ALA n 
1 107 ASN n 
1 108 PHE n 
1 109 HIS n 
1 110 GLU n 
1 111 VAL n 
1 112 THR n 
1 113 THR n 
1 114 ASP n 
1 115 ASN n 
1 116 LYS n 
1 117 LEU n 
1 118 LEU n 
1 119 ARG n 
1 120 ILE n 
1 121 PHE n 
1 122 LYS n 
1 123 ASN n 
1 124 GLY n 
1 125 ASN n 
1 126 VAL n 
1 127 LEU n 
1 128 TYR n 
1 129 SER n 
1 130 ILE n 
1 131 ARG n 
1 132 LEU n 
1 133 THR n 
1 134 LEU n 
1 135 THR n 
1 136 LEU n 
1 137 SER n 
1 138 CYS n 
1 139 PRO n 
1 140 MET n 
1 141 ASP n 
1 142 LEU n 
1 143 LYS n 
1 144 ASN n 
1 145 PHE n 
1 146 PRO n 
1 147 MET n 
1 148 ASP n 
1 149 VAL n 
1 150 GLN n 
1 151 THR n 
1 152 CYS n 
1 153 ILE n 
1 154 MET n 
1 155 GLN n 
1 156 LEU n 
1 157 GLU n 
1 158 SER n 
1 159 PHE n 
1 160 GLY n 
1 161 TYR n 
1 162 THR n 
1 163 MET n 
1 164 ASN n 
1 165 ASP n 
1 166 LEU n 
1 167 ILE n 
1 168 PHE n 
1 169 GLU n 
1 170 TRP n 
1 171 GLN n 
1 172 ASP n 
1 173 GLU n 
1 174 ALA n 
1 175 PRO n 
1 176 VAL n 
1 177 GLN n 
1 178 VAL n 
1 179 ALA n 
1 180 GLU n 
1 181 GLY n 
1 182 LEU n 
1 183 THR n 
1 184 LEU n 
1 185 PRO n 
1 186 GLN n 
1 187 PHE n 
1 188 LEU n 
1 189 LEU n 
1 190 LYS n 
1 191 GLU n 
1 192 GLU n 
1 193 LYS n 
1 194 ASP n 
1 195 LEU n 
1 196 ARG n 
1 197 TYR n 
1 198 CYS n 
1 199 THR n 
1 200 LYS n 
1 201 HIS n 
1 202 TYR n 
1 203 ASN n 
1 204 THR n 
1 205 GLY n 
1 206 LYS n 
1 207 PHE n 
1 208 THR n 
1 209 CYS n 
1 210 ILE n 
1 211 GLU n 
1 212 VAL n 
1 213 ARG n 
1 214 PHE n 
1 215 HIS n 
1 216 LEU n 
1 217 GLU n 
1 218 ARG n 
1 219 GLN n 
1 220 MET n 
1 221 GLY n 
1 222 TYR n 
1 223 TYR n 
1 224 LEU n 
1 225 ILE n 
1 226 GLN n 
1 227 MET n 
1 228 TYR n 
1 229 ILE n 
1 230 PRO n 
1 231 SER n 
1 232 LEU n 
1 233 LEU n 
1 234 ILE n 
1 235 VAL n 
1 236 ILE n 
1 237 LEU n 
1 238 SER n 
1 239 TRP n 
1 240 VAL n 
1 241 SER n 
1 242 PHE n 
1 243 TRP n 
1 244 ILE n 
1 245 ASN n 
1 246 MET n 
1 247 ASP n 
1 248 ALA n 
1 249 ALA n 
1 250 PRO n 
1 251 ALA n 
1 252 ARG n 
1 253 VAL n 
1 254 ALA n 
1 255 LEU n 
1 256 GLY n 
1 257 ILE n 
1 258 THR n 
1 259 THR n 
1 260 VAL n 
1 261 LEU n 
1 262 THR n 
1 263 MET n 
1 264 THR n 
1 265 THR n 
1 266 GLN n 
1 267 SER n 
1 268 SER n 
1 269 GLY n 
1 270 SER n 
1 271 ARG n 
1 272 ALA n 
1 273 SER n 
1 274 LEU n 
1 275 PRO n 
1 276 LYS n 
1 277 VAL n 
1 278 SER n 
1 279 TYR n 
1 280 VAL n 
1 281 LYS n 
1 282 ALA n 
1 283 ILE n 
1 284 ASP n 
1 285 ILE n 
1 286 TRP n 
1 287 MET n 
1 288 ALA n 
1 289 VAL n 
1 290 CYS n 
1 291 LEU n 
1 292 LEU n 
1 293 PHE n 
1 294 VAL n 
1 295 PHE n 
1 296 SER n 
1 297 ALA n 
1 298 LEU n 
1 299 LEU n 
1 300 GLU n 
1 301 TYR n 
1 302 ALA n 
1 303 ALA n 
1 304 VAL n 
1 305 ASN n 
1 306 PHE n 
1 307 VAL n 
1 308 SER n 
1 309 ARG n 
1 310 GLN n 
1 311 HIS n 
1 312 LYS n 
1 313 GLU n 
1 314 LEU n 
1 315 LEU n 
1 316 ARG n 
1 317 PHE n 
1 318 ARG n 
1 319 ARG n 
1 320 LYS n 
1 321 ARG n 
1 322 LYS n 
1 323 ASN n 
1 324 LYS n 
1 325 THR n 
1 326 GLU n 
1 327 ALA n 
1 328 PHE n 
1 329 ASP n 
1 330 MET n 
1 331 ASP n 
1 332 ASP n 
1 333 GLU n 
1 334 VAL n 
1 335 ARG n 
1 336 GLU n 
1 337 GLU n 
1 338 ARG n 
1 339 PHE n 
1 340 SER n 
1 341 PHE n 
1 342 THR n 
1 343 ALA n 
1 344 TYR n 
1 345 GLY n 
1 346 MET n 
1 347 GLY n 
1 348 PRO n 
1 349 CYS n 
1 350 LEU n 
1 351 GLN n 
1 352 ALA n 
1 353 LYS n 
1 354 ASP n 
1 355 GLY n 
1 356 MET n 
1 357 THR n 
1 358 PRO n 
1 359 LYS n 
1 360 GLY n 
1 361 PRO n 
1 362 ASN n 
1 363 HIS n 
1 364 PRO n 
1 365 VAL n 
1 366 GLN n 
1 367 VAL n 
1 368 MET n 
1 369 PRO n 
1 370 LYS n 
1 371 SER n 
1 372 PRO n 
1 373 ASP n 
1 374 GLU n 
1 375 MET n 
1 376 ARG n 
1 377 LYS n 
1 378 VAL n 
1 379 PHE n 
1 380 ILE n 
1 381 ASP n 
1 382 ARG n 
1 383 ALA n 
1 384 LYS n 
1 385 LYS n 
1 386 ILE n 
1 387 ASP n 
1 388 THR n 
1 389 ILE n 
1 390 SER n 
1 391 ARG n 
1 392 ALA n 
1 393 CYS n 
1 394 PHE n 
1 395 PRO n 
1 396 LEU n 
1 397 ALA n 
1 398 PHE n 
1 399 LEU n 
1 400 ILE n 
1 401 PHE n 
1 402 ASN n 
1 403 ILE n 
1 404 PHE n 
1 405 TYR n 
1 406 TRP n 
1 407 VAL n 
1 408 ILE n 
1 409 TYR n 
1 410 LYS n 
1 411 ILE n 
1 412 LEU n 
1 413 ARG n 
1 414 HIS n 
1 415 GLU n 
1 416 ASP n 
1 417 ILE n 
1 418 HIS n 
1 419 GLN n 
1 420 GLN n 
1 421 GLN n 
1 422 ASP n 
2 1   LYS n 
2 2   SER n 
2 3   SER n 
2 4   LYS n 
2 5   LYS n 
2 6   GLY n 
2 7   LYS n 
2 8   GLY n 
2 9   LYS n 
2 10  LYS n 
2 11  LYS n 
2 12  GLN n 
2 13  TYR n 
2 14  LEU n 
2 15  CYS n 
2 16  PRO n 
2 17  SER n 
2 18  GLN n 
2 19  GLN n 
2 20  SER n 
2 21  ALA n 
2 22  GLU n 
2 23  ASP n 
2 24  LEU n 
2 25  ALA n 
2 26  ARG n 
2 27  VAL n 
2 28  PRO n 
2 29  ALA n 
2 30  ASN n 
2 31  SER n 
2 32  THR n 
2 33  SER n 
2 34  ASN n 
2 35  ILE n 
2 36  LEU n 
2 37  ASN n 
2 38  ARG n 
2 39  LEU n 
2 40  LEU n 
2 41  VAL n 
2 42  SER n 
2 43  TYR n 
2 44  ASP n 
2 45  PRO n 
2 46  ARG n 
2 47  ILE n 
2 48  ARG n 
2 49  PRO n 
2 50  ASN n 
2 51  PHE n 
2 52  LYS n 
2 53  GLY n 
2 54  ILE n 
2 55  PRO n 
2 56  VAL n 
2 57  ASP n 
2 58  VAL n 
2 59  VAL n 
2 60  VAL n 
2 61  ASN n 
2 62  ILE n 
2 63  PHE n 
2 64  ILE n 
2 65  ASN n 
2 66  SER n 
2 67  PHE n 
2 68  GLY n 
2 69  SER n 
2 70  ILE n 
2 71  GLN n 
2 72  GLU n 
2 73  THR n 
2 74  THR n 
2 75  MET n 
2 76  ASP n 
2 77  TYR n 
2 78  ARG n 
2 79  VAL n 
2 80  ASN n 
2 81  ILE n 
2 82  PHE n 
2 83  LEU n 
2 84  ARG n 
2 85  GLN n 
2 86  LYS n 
2 87  TRP n 
2 88  ASN n 
2 89  ASP n 
2 90  PRO n 
2 91  ARG n 
2 92  LEU n 
2 93  LYS n 
2 94  LEU n 
2 95  PRO n 
2 96  SER n 
2 97  ASP n 
2 98  PHE n 
2 99  ARG n 
2 100 GLY n 
2 101 SER n 
2 102 ASP n 
2 103 ALA n 
2 104 LEU n 
2 105 THR n 
2 106 VAL n 
2 107 ASP n 
2 108 PRO n 
2 109 THR n 
2 110 MET n 
2 111 TYR n 
2 112 LYS n 
2 113 CYS n 
2 114 LEU n 
2 115 TRP n 
2 116 LYS n 
2 117 PRO n 
2 118 ASP n 
2 119 LEU n 
2 120 PHE n 
2 121 PHE n 
2 122 ALA n 
2 123 ASN n 
2 124 GLU n 
2 125 LYS n 
2 126 SER n 
2 127 ALA n 
2 128 ASN n 
2 129 PHE n 
2 130 HIS n 
2 131 ASP n 
2 132 VAL n 
2 133 THR n 
2 134 GLN n 
2 135 GLU n 
2 136 ASN n 
2 137 ILE n 
2 138 LEU n 
2 139 LEU n 
2 140 PHE n 
2 141 ILE n 
2 142 PHE n 
2 143 ARG n 
2 144 ASP n 
2 145 GLY n 
2 146 ASP n 
2 147 VAL n 
2 148 LEU n 
2 149 VAL n 
2 150 SER n 
2 151 MET n 
2 152 ARG n 
2 153 LEU n 
2 154 SER n 
2 155 ILE n 
2 156 THR n 
2 157 LEU n 
2 158 SER n 
2 159 CYS n 
2 160 PRO n 
2 161 LEU n 
2 162 ASP n 
2 163 LEU n 
2 164 THR n 
2 165 LEU n 
2 166 PHE n 
2 167 PRO n 
2 168 MET n 
2 169 ASP n 
2 170 THR n 
2 171 GLN n 
2 172 ARG n 
2 173 CYS n 
2 174 LYS n 
2 175 MET n 
2 176 GLN n 
2 177 LEU n 
2 178 GLU n 
2 179 SER n 
2 180 PHE n 
2 181 GLY n 
2 182 TYR n 
2 183 THR n 
2 184 THR n 
2 185 ASP n 
2 186 ASP n 
2 187 LEU n 
2 188 ARG n 
2 189 PHE n 
2 190 ILE n 
2 191 TRP n 
2 192 GLN n 
2 193 SER n 
2 194 GLY n 
2 195 ASP n 
2 196 PRO n 
2 197 VAL n 
2 198 GLN n 
2 199 LEU n 
2 200 GLU n 
2 201 LYS n 
2 202 ILE n 
2 203 ALA n 
2 204 LEU n 
2 205 PRO n 
2 206 GLN n 
2 207 PHE n 
2 208 ASP n 
2 209 ILE n 
2 210 LYS n 
2 211 LYS n 
2 212 GLU n 
2 213 ASP n 
2 214 ILE n 
2 215 GLU n 
2 216 TYR n 
2 217 GLY n 
2 218 ASN n 
2 219 CYS n 
2 220 THR n 
2 221 LYS n 
2 222 TYR n 
2 223 TYR n 
2 224 LYS n 
2 225 GLY n 
2 226 THR n 
2 227 GLY n 
2 228 TYR n 
2 229 TYR n 
2 230 THR n 
2 231 CYS n 
2 232 VAL n 
2 233 GLU n 
2 234 VAL n 
2 235 ILE n 
2 236 PHE n 
2 237 THR n 
2 238 LEU n 
2 239 ARG n 
2 240 ARG n 
2 241 GLN n 
2 242 VAL n 
2 243 GLY n 
2 244 PHE n 
2 245 TYR n 
2 246 MET n 
2 247 MET n 
2 248 GLY n 
2 249 VAL n 
2 250 TYR n 
2 251 ALA n 
2 252 PRO n 
2 253 THR n 
2 254 LEU n 
2 255 LEU n 
2 256 ILE n 
2 257 VAL n 
2 258 VAL n 
2 259 LEU n 
2 260 SER n 
2 261 TRP n 
2 262 LEU n 
2 263 SER n 
2 264 PHE n 
2 265 TRP n 
2 266 ILE n 
2 267 ASN n 
2 268 PRO n 
2 269 ASP n 
2 270 ALA n 
2 271 SER n 
2 272 ALA n 
2 273 ALA n 
2 274 ARG n 
2 275 VAL n 
2 276 PRO n 
2 277 LEU n 
2 278 GLY n 
2 279 ILE n 
2 280 PHE n 
2 281 SER n 
2 282 VAL n 
2 283 LEU n 
2 284 SER n 
2 285 LEU n 
2 286 ALA n 
2 287 SER n 
2 288 GLU n 
2 289 CYS n 
2 290 THR n 
2 291 THR n 
2 292 LEU n 
2 293 ALA n 
2 294 ALA n 
2 295 GLU n 
2 296 LEU n 
2 297 PRO n 
2 298 LYS n 
2 299 VAL n 
2 300 SER n 
2 301 TYR n 
2 302 VAL n 
2 303 LYS n 
2 304 ALA n 
2 305 LEU n 
2 306 ASP n 
2 307 VAL n 
2 308 TRP n 
2 309 LEU n 
2 310 ILE n 
2 311 ALA n 
2 312 CYS n 
2 313 LEU n 
2 314 LEU n 
2 315 PHE n 
2 316 GLY n 
2 317 PHE n 
2 318 ALA n 
2 319 SER n 
2 320 LEU n 
2 321 VAL n 
2 322 GLU n 
2 323 TYR n 
2 324 ALA n 
2 325 VAL n 
2 326 VAL n 
2 327 GLN n 
2 328 VAL n 
2 329 MET n 
2 330 LEU n 
2 331 ASN n 
2 332 GLY n 
2 333 GLY n 
2 334 SER n 
2 335 SER n 
2 336 ALA n 
2 337 ALA n 
2 338 ALA n 
2 339 VAL n 
2 340 SER n 
2 341 LYS n 
2 342 GLY n 
2 343 GLU n 
2 344 GLU n 
2 345 LEU n 
2 346 PHE n 
2 347 THR n 
2 348 GLY n 
2 349 VAL n 
2 350 VAL n 
2 351 PRO n 
2 352 ILE n 
2 353 LEU n 
2 354 VAL n 
2 355 GLU n 
2 356 LEU n 
2 357 ASP n 
2 358 GLY n 
2 359 ASP n 
2 360 VAL n 
2 361 ASN n 
2 362 GLY n 
2 363 HIS n 
2 364 LYS n 
2 365 PHE n 
2 366 SER n 
2 367 VAL n 
2 368 SER n 
2 369 GLY n 
2 370 GLU n 
2 371 GLY n 
2 372 GLU n 
2 373 GLY n 
2 374 ASP n 
2 375 ALA n 
2 376 THR n 
2 377 TYR n 
2 378 GLY n 
2 379 LYS n 
2 380 LEU n 
2 381 THR n 
2 382 LEU n 
2 383 LYS n 
2 384 PHE n 
2 385 ILE n 
2 386 CYS n 
2 387 THR n 
2 388 THR n 
2 389 GLY n 
2 390 LYS n 
2 391 LEU n 
2 392 PRO n 
2 393 VAL n 
2 394 PRO n 
2 395 TRP n 
2 396 PRO n 
2 397 THR n 
2 398 LEU n 
2 399 VAL n 
2 400 THR n 
2 401 THR n 
2 402 PHE n 
2 403 SER n 
2 404 TYR n 
2 405 GLY n 
2 406 VAL n 
2 407 GLN n 
2 408 CYS n 
2 409 PHE n 
2 410 SER n 
2 411 ARG n 
2 412 TYR n 
2 413 PRO n 
2 414 ASP n 
2 415 HIS n 
2 416 MET n 
2 417 LYS n 
2 418 GLN n 
2 419 HIS n 
2 420 ASP n 
2 421 PHE n 
2 422 PHE n 
2 423 LYS n 
2 424 SER n 
2 425 ALA n 
2 426 MET n 
2 427 PRO n 
2 428 GLU n 
2 429 GLY n 
2 430 TYR n 
2 431 VAL n 
2 432 GLN n 
2 433 GLU n 
2 434 ARG n 
2 435 THR n 
2 436 ILE n 
2 437 PHE n 
2 438 PHE n 
2 439 LYS n 
2 440 ASP n 
2 441 ASP n 
2 442 GLY n 
2 443 ASN n 
2 444 TYR n 
2 445 LYS n 
2 446 THR n 
2 447 ARG n 
2 448 ALA n 
2 449 GLU n 
2 450 VAL n 
2 451 LYS n 
2 452 PHE n 
2 453 GLU n 
2 454 GLY n 
2 455 ASP n 
2 456 THR n 
2 457 LEU n 
2 458 VAL n 
2 459 ASN n 
2 460 ARG n 
2 461 ILE n 
2 462 GLU n 
2 463 LEU n 
2 464 LYS n 
2 465 GLY n 
2 466 ILE n 
2 467 ASP n 
2 468 PHE n 
2 469 LYS n 
2 470 GLU n 
2 471 ASP n 
2 472 GLY n 
2 473 ASN n 
2 474 ILE n 
2 475 LEU n 
2 476 GLY n 
2 477 HIS n 
2 478 LYS n 
2 479 LEU n 
2 480 GLU n 
2 481 TYR n 
2 482 ASN n 
2 483 TYR n 
2 484 ASN n 
2 485 SER n 
2 486 HIS n 
2 487 ASN n 
2 488 VAL n 
2 489 TYR n 
2 490 ILE n 
2 491 MET n 
2 492 ALA n 
2 493 ASP n 
2 494 LYS n 
2 495 GLN n 
2 496 LYS n 
2 497 ASN n 
2 498 GLY n 
2 499 ILE n 
2 500 LYS n 
2 501 VAL n 
2 502 ASN n 
2 503 PHE n 
2 504 LYS n 
2 505 ILE n 
2 506 ARG n 
2 507 HIS n 
2 508 ASN n 
2 509 ILE n 
2 510 GLU n 
2 511 ASP n 
2 512 GLY n 
2 513 SER n 
2 514 VAL n 
2 515 GLN n 
2 516 LEU n 
2 517 ALA n 
2 518 ASP n 
2 519 HIS n 
2 520 TYR n 
2 521 GLN n 
2 522 GLN n 
2 523 ASN n 
2 524 THR n 
2 525 PRO n 
2 526 ILE n 
2 527 GLY n 
2 528 ASP n 
2 529 GLY n 
2 530 PRO n 
2 531 VAL n 
2 532 LEU n 
2 533 LEU n 
2 534 PRO n 
2 535 ASP n 
2 536 ASN n 
2 537 HIS n 
2 538 TYR n 
2 539 LEU n 
2 540 SER n 
2 541 THR n 
2 542 GLN n 
2 543 SER n 
2 544 ALA n 
2 545 LEU n 
2 546 SER n 
2 547 LYS n 
2 548 ASP n 
2 549 PRO n 
2 550 ASN n 
2 551 GLU n 
2 552 LYS n 
2 553 ARG n 
2 554 ASP n 
2 555 HIS n 
2 556 MET n 
2 557 VAL n 
2 558 LEU n 
2 559 LEU n 
2 560 GLU n 
2 561 PHE n 
2 562 VAL n 
2 563 THR n 
2 564 ALA n 
2 565 ALA n 
2 566 GLY n 
2 567 ILE n 
2 568 THR n 
2 569 HIS n 
2 570 GLY n 
2 571 MET n 
2 572 ASP n 
2 573 GLU n 
2 574 LEU n 
2 575 TYR n 
2 576 LYS n 
2 577 SER n 
2 578 GLY n 
2 579 SER n 
2 580 GLY n 
2 581 SER n 
2 582 GLY n 
2 583 VAL n 
2 584 GLY n 
2 585 GLU n 
2 586 THR n 
2 587 ARG n 
2 588 CYS n 
2 589 LYS n 
2 590 LYS n 
2 591 VAL n 
2 592 CYS n 
2 593 THR n 
2 594 SER n 
2 595 LYS n 
2 596 SER n 
2 597 ASP n 
2 598 LEU n 
2 599 ARG n 
2 600 SER n 
2 601 ASN n 
2 602 ASP n 
2 603 PHE n 
2 604 SER n 
2 605 ILE n 
2 606 VAL n 
2 607 GLY n 
2 608 SER n 
2 609 LEU n 
2 610 PRO n 
2 611 ARG n 
2 612 ASP n 
2 613 PHE n 
2 614 GLU n 
2 615 LEU n 
2 616 SER n 
2 617 ASN n 
2 618 TYR n 
2 619 ASP n 
2 620 CYS n 
2 621 TYR n 
2 622 GLY n 
2 623 LYS n 
2 624 PRO n 
2 625 ILE n 
2 626 GLU n 
2 627 VAL n 
2 628 ASN n 
2 629 ASN n 
2 630 GLY n 
2 631 LEU n 
2 632 GLY n 
2 633 LYS n 
2 634 SER n 
2 635 GLN n 
2 636 ALA n 
2 637 LYS n 
2 638 ASN n 
2 639 ASN n 
2 640 LYS n 
2 641 LYS n 
2 642 PRO n 
2 643 PRO n 
2 644 PRO n 
2 645 ALA n 
2 646 LYS n 
2 647 PRO n 
2 648 VAL n 
2 649 ILE n 
2 650 PRO n 
2 651 THR n 
2 652 ALA n 
2 653 ALA n 
2 654 LYS n 
2 655 ARG n 
2 656 ILE n 
2 657 ASP n 
2 658 LEU n 
2 659 TYR n 
2 660 ALA n 
2 661 ARG n 
2 662 ALA n 
2 663 LEU n 
2 664 PHE n 
2 665 PRO n 
2 666 PHE n 
2 667 CYS n 
2 668 PHE n 
2 669 LEU n 
2 670 PHE n 
2 671 PHE n 
2 672 ASN n 
2 673 VAL n 
2 674 ILE n 
2 675 TYR n 
2 676 TRP n 
2 677 SER n 
2 678 ILE n 
2 679 TYR n 
2 680 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   422 human ? GLRA3       ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   331 human ? GLRB        ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 2 sample 'Biological sequence' 332 582 human ? MMB69_26960 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 3 sample 'Biological sequence' 583 680 human ? GLRB        ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   1   ?   ?   ?   A . n 
A 1 2   ARG 2   2   ?   ?   ?   A . n 
A 1 3   SER 3   3   ?   ?   ?   A . n 
A 1 4   ARG 4   4   ?   ?   ?   A . n 
A 1 5   SER 5   5   ?   ?   ?   A . n 
A 1 6   ALA 6   6   ?   ?   ?   A . n 
A 1 7   PRO 7   7   ?   ?   ?   A . n 
A 1 8   MET 8   8   8   MET MET A . n 
A 1 9   SER 9   9   9   SER SER A . n 
A 1 10  PRO 10  10  10  PRO PRO A . n 
A 1 11  SER 11  11  11  SER SER A . n 
A 1 12  ASP 12  12  12  ASP ASP A . n 
A 1 13  PHE 13  13  13  PHE PHE A . n 
A 1 14  LEU 14  14  14  LEU LEU A . n 
A 1 15  ASP 15  15  15  ASP ASP A . n 
A 1 16  LYS 16  16  16  LYS LYS A . n 
A 1 17  LEU 17  17  17  LEU LEU A . n 
A 1 18  MET 18  18  18  MET MET A . n 
A 1 19  GLY 19  19  19  GLY GLY A . n 
A 1 20  ARG 20  20  20  ARG ARG A . n 
A 1 21  THR 21  21  21  THR THR A . n 
A 1 22  SER 22  22  22  SER SER A . n 
A 1 23  GLY 23  23  23  GLY GLY A . n 
A 1 24  TYR 24  24  24  TYR TYR A . n 
A 1 25  ASP 25  25  25  ASP ASP A . n 
A 1 26  ALA 26  26  26  ALA ALA A . n 
A 1 27  ARG 27  27  27  ARG ARG A . n 
A 1 28  ILE 28  28  28  ILE ILE A . n 
A 1 29  ARG 29  29  29  ARG ARG A . n 
A 1 30  PRO 30  30  30  PRO PRO A . n 
A 1 31  ASN 31  31  31  ASN ASN A . n 
A 1 32  PHE 32  32  32  PHE PHE A . n 
A 1 33  LYS 33  33  33  LYS LYS A . n 
A 1 34  GLY 34  34  34  GLY GLY A . n 
A 1 35  PRO 35  35  35  PRO PRO A . n 
A 1 36  PRO 36  36  36  PRO PRO A . n 
A 1 37  VAL 37  37  37  VAL VAL A . n 
A 1 38  ASN 38  38  38  ASN ASN A . n 
A 1 39  VAL 39  39  39  VAL VAL A . n 
A 1 40  THR 40  40  40  THR THR A . n 
A 1 41  CYS 41  41  41  CYS CYS A . n 
A 1 42  ASN 42  42  42  ASN ASN A . n 
A 1 43  ILE 43  43  43  ILE ILE A . n 
A 1 44  PHE 44  44  44  PHE PHE A . n 
A 1 45  ILE 45  45  45  ILE ILE A . n 
A 1 46  ASN 46  46  46  ASN ASN A . n 
A 1 47  SER 47  47  47  SER SER A . n 
A 1 48  PHE 48  48  48  PHE PHE A . n 
A 1 49  GLY 49  49  49  GLY GLY A . n 
A 1 50  SER 50  50  50  SER SER A . n 
A 1 51  ILE 51  51  51  ILE ILE A . n 
A 1 52  ALA 52  52  52  ALA ALA A . n 
A 1 53  GLU 53  53  53  GLU GLU A . n 
A 1 54  THR 54  54  54  THR THR A . n 
A 1 55  THR 55  55  55  THR THR A . n 
A 1 56  MET 56  56  56  MET MET A . n 
A 1 57  ASP 57  57  57  ASP ASP A . n 
A 1 58  TYR 58  58  58  TYR TYR A . n 
A 1 59  ARG 59  59  59  ARG ARG A . n 
A 1 60  VAL 60  60  60  VAL VAL A . n 
A 1 61  ASN 61  61  61  ASN ASN A . n 
A 1 62  ILE 62  62  62  ILE ILE A . n 
A 1 63  PHE 63  63  63  PHE PHE A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  ARG 65  65  65  ARG ARG A . n 
A 1 66  GLN 66  66  66  GLN GLN A . n 
A 1 67  LYS 67  67  67  LYS LYS A . n 
A 1 68  TRP 68  68  68  TRP TRP A . n 
A 1 69  ASN 69  69  69  ASN ASN A . n 
A 1 70  ASP 70  70  70  ASP ASP A . n 
A 1 71  PRO 71  71  71  PRO PRO A . n 
A 1 72  ARG 72  72  72  ARG ARG A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  ALA 74  74  74  ALA ALA A . n 
A 1 75  TYR 75  75  75  TYR TYR A . n 
A 1 76  SER 76  76  76  SER SER A . n 
A 1 77  GLU 77  77  77  GLU GLU A . n 
A 1 78  TYR 78  78  78  TYR TYR A . n 
A 1 79  PRO 79  79  79  PRO PRO A . n 
A 1 80  ASP 80  80  80  ASP ASP A . n 
A 1 81  ASP 81  81  81  ASP ASP A . n 
A 1 82  SER 82  82  82  SER SER A . n 
A 1 83  LEU 83  83  83  LEU LEU A . n 
A 1 84  ASP 84  84  84  ASP ASP A . n 
A 1 85  LEU 85  85  85  LEU LEU A . n 
A 1 86  ASP 86  86  86  ASP ASP A . n 
A 1 87  PRO 87  87  87  PRO PRO A . n 
A 1 88  SER 88  88  88  SER SER A . n 
A 1 89  MET 89  89  89  MET MET A . n 
A 1 90  LEU 90  90  90  LEU LEU A . n 
A 1 91  ASP 91  91  91  ASP ASP A . n 
A 1 92  SER 92  92  92  SER SER A . n 
A 1 93  ILE 93  93  93  ILE ILE A . n 
A 1 94  TRP 94  94  94  TRP TRP A . n 
A 1 95  LYS 95  95  95  LYS LYS A . n 
A 1 96  PRO 96  96  96  PRO PRO A . n 
A 1 97  ASP 97  97  97  ASP ASP A . n 
A 1 98  LEU 98  98  98  LEU LEU A . n 
A 1 99  PHE 99  99  99  PHE PHE A . n 
A 1 100 PHE 100 100 100 PHE PHE A . n 
A 1 101 ALA 101 101 101 ALA ALA A . n 
A 1 102 ASN 102 102 102 ASN ASN A . n 
A 1 103 GLU 103 103 103 GLU GLU A . n 
A 1 104 LYS 104 104 104 LYS LYS A . n 
A 1 105 GLY 105 105 105 GLY GLY A . n 
A 1 106 ALA 106 106 106 ALA ALA A . n 
A 1 107 ASN 107 107 107 ASN ASN A . n 
A 1 108 PHE 108 108 108 PHE PHE A . n 
A 1 109 HIS 109 109 109 HIS HIS A . n 
A 1 110 GLU 110 110 110 GLU GLU A . n 
A 1 111 VAL 111 111 111 VAL VAL A . n 
A 1 112 THR 112 112 112 THR THR A . n 
A 1 113 THR 113 113 113 THR THR A . n 
A 1 114 ASP 114 114 114 ASP ASP A . n 
A 1 115 ASN 115 115 115 ASN ASN A . n 
A 1 116 LYS 116 116 116 LYS LYS A . n 
A 1 117 LEU 117 117 117 LEU LEU A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 ARG 119 119 119 ARG ARG A . n 
A 1 120 ILE 120 120 120 ILE ILE A . n 
A 1 121 PHE 121 121 121 PHE PHE A . n 
A 1 122 LYS 122 122 122 LYS LYS A . n 
A 1 123 ASN 123 123 123 ASN ASN A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 ASN 125 125 125 ASN ASN A . n 
A 1 126 VAL 126 126 126 VAL VAL A . n 
A 1 127 LEU 127 127 127 LEU LEU A . n 
A 1 128 TYR 128 128 128 TYR TYR A . n 
A 1 129 SER 129 129 129 SER SER A . n 
A 1 130 ILE 130 130 130 ILE ILE A . n 
A 1 131 ARG 131 131 131 ARG ARG A . n 
A 1 132 LEU 132 132 132 LEU LEU A . n 
A 1 133 THR 133 133 133 THR THR A . n 
A 1 134 LEU 134 134 134 LEU LEU A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 LEU 136 136 136 LEU LEU A . n 
A 1 137 SER 137 137 137 SER SER A . n 
A 1 138 CYS 138 138 138 CYS CYS A . n 
A 1 139 PRO 139 139 139 PRO PRO A . n 
A 1 140 MET 140 140 140 MET MET A . n 
A 1 141 ASP 141 141 141 ASP ASP A . n 
A 1 142 LEU 142 142 142 LEU LEU A . n 
A 1 143 LYS 143 143 143 LYS LYS A . n 
A 1 144 ASN 144 144 144 ASN ASN A . n 
A 1 145 PHE 145 145 145 PHE PHE A . n 
A 1 146 PRO 146 146 146 PRO PRO A . n 
A 1 147 MET 147 147 147 MET MET A . n 
A 1 148 ASP 148 148 148 ASP ASP A . n 
A 1 149 VAL 149 149 149 VAL VAL A . n 
A 1 150 GLN 150 150 150 GLN GLN A . n 
A 1 151 THR 151 151 151 THR THR A . n 
A 1 152 CYS 152 152 152 CYS CYS A . n 
A 1 153 ILE 153 153 153 ILE ILE A . n 
A 1 154 MET 154 154 154 MET MET A . n 
A 1 155 GLN 155 155 155 GLN GLN A . n 
A 1 156 LEU 156 156 156 LEU LEU A . n 
A 1 157 GLU 157 157 157 GLU GLU A . n 
A 1 158 SER 158 158 158 SER SER A . n 
A 1 159 PHE 159 159 159 PHE PHE A . n 
A 1 160 GLY 160 160 160 GLY GLY A . n 
A 1 161 TYR 161 161 161 TYR TYR A . n 
A 1 162 THR 162 162 162 THR THR A . n 
A 1 163 MET 163 163 163 MET MET A . n 
A 1 164 ASN 164 164 164 ASN ASN A . n 
A 1 165 ASP 165 165 165 ASP ASP A . n 
A 1 166 LEU 166 166 166 LEU LEU A . n 
A 1 167 ILE 167 167 167 ILE ILE A . n 
A 1 168 PHE 168 168 168 PHE PHE A . n 
A 1 169 GLU 169 169 169 GLU GLU A . n 
A 1 170 TRP 170 170 170 TRP TRP A . n 
A 1 171 GLN 171 171 171 GLN GLN A . n 
A 1 172 ASP 172 172 172 ASP ASP A . n 
A 1 173 GLU 173 173 173 GLU GLU A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 PRO 175 175 175 PRO PRO A . n 
A 1 176 VAL 176 176 176 VAL VAL A . n 
A 1 177 GLN 177 177 177 GLN GLN A . n 
A 1 178 VAL 178 178 178 VAL VAL A . n 
A 1 179 ALA 179 179 179 ALA ALA A . n 
A 1 180 GLU 180 180 180 GLU GLU A . n 
A 1 181 GLY 181 181 181 GLY GLY A . n 
A 1 182 LEU 182 182 182 LEU LEU A . n 
A 1 183 THR 183 183 183 THR THR A . n 
A 1 184 LEU 184 184 184 LEU LEU A . n 
A 1 185 PRO 185 185 185 PRO PRO A . n 
A 1 186 GLN 186 186 186 GLN GLN A . n 
A 1 187 PHE 187 187 187 PHE PHE A . n 
A 1 188 LEU 188 188 188 LEU LEU A . n 
A 1 189 LEU 189 189 189 LEU LEU A . n 
A 1 190 LYS 190 190 190 LYS LYS A . n 
A 1 191 GLU 191 191 191 GLU GLU A . n 
A 1 192 GLU 192 192 192 GLU GLU A . n 
A 1 193 LYS 193 193 193 LYS LYS A . n 
A 1 194 ASP 194 194 194 ASP ASP A . n 
A 1 195 LEU 195 195 195 LEU LEU A . n 
A 1 196 ARG 196 196 196 ARG ARG A . n 
A 1 197 TYR 197 197 197 TYR TYR A . n 
A 1 198 CYS 198 198 198 CYS CYS A . n 
A 1 199 THR 199 199 199 THR THR A . n 
A 1 200 LYS 200 200 200 LYS LYS A . n 
A 1 201 HIS 201 201 201 HIS HIS A . n 
A 1 202 TYR 202 202 202 TYR TYR A . n 
A 1 203 ASN 203 203 203 ASN ASN A . n 
A 1 204 THR 204 204 204 THR THR A . n 
A 1 205 GLY 205 205 205 GLY GLY A . n 
A 1 206 LYS 206 206 206 LYS LYS A . n 
A 1 207 PHE 207 207 207 PHE PHE A . n 
A 1 208 THR 208 208 208 THR THR A . n 
A 1 209 CYS 209 209 209 CYS CYS A . n 
A 1 210 ILE 210 210 210 ILE ILE A . n 
A 1 211 GLU 211 211 211 GLU GLU A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 ARG 213 213 213 ARG ARG A . n 
A 1 214 PHE 214 214 214 PHE PHE A . n 
A 1 215 HIS 215 215 215 HIS HIS A . n 
A 1 216 LEU 216 216 216 LEU LEU A . n 
A 1 217 GLU 217 217 217 GLU GLU A . n 
A 1 218 ARG 218 218 218 ARG ARG A . n 
A 1 219 GLN 219 219 219 GLN GLN A . n 
A 1 220 MET 220 220 220 MET MET A . n 
A 1 221 GLY 221 221 221 GLY GLY A . n 
A 1 222 TYR 222 222 222 TYR TYR A . n 
A 1 223 TYR 223 223 223 TYR TYR A . n 
A 1 224 LEU 224 224 224 LEU LEU A . n 
A 1 225 ILE 225 225 225 ILE ILE A . n 
A 1 226 GLN 226 226 226 GLN GLN A . n 
A 1 227 MET 227 227 227 MET MET A . n 
A 1 228 TYR 228 228 228 TYR TYR A . n 
A 1 229 ILE 229 229 229 ILE ILE A . n 
A 1 230 PRO 230 230 230 PRO PRO A . n 
A 1 231 SER 231 231 231 SER SER A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 LEU 233 233 233 LEU LEU A . n 
A 1 234 ILE 234 234 234 ILE ILE A . n 
A 1 235 VAL 235 235 235 VAL VAL A . n 
A 1 236 ILE 236 236 236 ILE ILE A . n 
A 1 237 LEU 237 237 237 LEU LEU A . n 
A 1 238 SER 238 238 238 SER SER A . n 
A 1 239 TRP 239 239 239 TRP TRP A . n 
A 1 240 VAL 240 240 240 VAL VAL A . n 
A 1 241 SER 241 241 241 SER SER A . n 
A 1 242 PHE 242 242 242 PHE PHE A . n 
A 1 243 TRP 243 243 243 TRP TRP A . n 
A 1 244 ILE 244 244 244 ILE ILE A . n 
A 1 245 ASN 245 245 245 ASN ASN A . n 
A 1 246 MET 246 246 246 MET MET A . n 
A 1 247 ASP 247 247 247 ASP ASP A . n 
A 1 248 ALA 248 248 248 ALA ALA A . n 
A 1 249 ALA 249 249 249 ALA ALA A . n 
A 1 250 PRO 250 250 250 PRO PRO A . n 
A 1 251 ALA 251 251 251 ALA ALA A . n 
A 1 252 ARG 252 252 252 ARG ARG A . n 
A 1 253 VAL 253 253 253 VAL VAL A . n 
A 1 254 ALA 254 254 254 ALA ALA A . n 
A 1 255 LEU 255 255 255 LEU LEU A . n 
A 1 256 GLY 256 256 256 GLY GLY A . n 
A 1 257 ILE 257 257 257 ILE ILE A . n 
A 1 258 THR 258 258 258 THR THR A . n 
A 1 259 THR 259 259 259 THR THR A . n 
A 1 260 VAL 260 260 260 VAL VAL A . n 
A 1 261 LEU 261 261 261 LEU LEU A . n 
A 1 262 THR 262 262 262 THR THR A . n 
A 1 263 MET 263 263 263 MET MET A . n 
A 1 264 THR 264 264 264 THR THR A . n 
A 1 265 THR 265 265 265 THR THR A . n 
A 1 266 GLN 266 266 266 GLN GLN A . n 
A 1 267 SER 267 267 267 SER SER A . n 
A 1 268 SER 268 268 268 SER SER A . n 
A 1 269 GLY 269 269 269 GLY GLY A . n 
A 1 270 SER 270 270 270 SER SER A . n 
A 1 271 ARG 271 271 271 ARG ARG A . n 
A 1 272 ALA 272 272 272 ALA ALA A . n 
A 1 273 SER 273 273 273 SER SER A . n 
A 1 274 LEU 274 274 274 LEU LEU A . n 
A 1 275 PRO 275 275 275 PRO PRO A . n 
A 1 276 LYS 276 276 276 LYS LYS A . n 
A 1 277 VAL 277 277 277 VAL VAL A . n 
A 1 278 SER 278 278 278 SER SER A . n 
A 1 279 TYR 279 279 279 TYR TYR A . n 
A 1 280 VAL 280 280 280 VAL VAL A . n 
A 1 281 LYS 281 281 281 LYS LYS A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 ILE 283 283 283 ILE ILE A . n 
A 1 284 ASP 284 284 284 ASP ASP A . n 
A 1 285 ILE 285 285 285 ILE ILE A . n 
A 1 286 TRP 286 286 286 TRP TRP A . n 
A 1 287 MET 287 287 287 MET MET A . n 
A 1 288 ALA 288 288 288 ALA ALA A . n 
A 1 289 VAL 289 289 289 VAL VAL A . n 
A 1 290 CYS 290 290 290 CYS CYS A . n 
A 1 291 LEU 291 291 291 LEU LEU A . n 
A 1 292 LEU 292 292 292 LEU LEU A . n 
A 1 293 PHE 293 293 293 PHE PHE A . n 
A 1 294 VAL 294 294 294 VAL VAL A . n 
A 1 295 PHE 295 295 295 PHE PHE A . n 
A 1 296 SER 296 296 296 SER SER A . n 
A 1 297 ALA 297 297 297 ALA ALA A . n 
A 1 298 LEU 298 298 298 LEU LEU A . n 
A 1 299 LEU 299 299 299 LEU LEU A . n 
A 1 300 GLU 300 300 300 GLU GLU A . n 
A 1 301 TYR 301 301 301 TYR TYR A . n 
A 1 302 ALA 302 302 302 ALA ALA A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 VAL 304 304 304 VAL VAL A . n 
A 1 305 ASN 305 305 305 ASN ASN A . n 
A 1 306 PHE 306 306 306 PHE PHE A . n 
A 1 307 VAL 307 307 307 VAL VAL A . n 
A 1 308 SER 308 308 308 SER SER A . n 
A 1 309 ARG 309 309 309 ARG ARG A . n 
A 1 310 GLN 310 310 310 GLN GLN A . n 
A 1 311 HIS 311 320 ?   ?   ?   A . n 
A 1 312 LYS 312 321 ?   ?   ?   A . n 
A 1 313 GLU 313 322 ?   ?   ?   A . n 
A 1 314 LEU 314 323 ?   ?   ?   A . n 
A 1 315 LEU 315 324 ?   ?   ?   A . n 
A 1 316 ARG 316 325 ?   ?   ?   A . n 
A 1 317 PHE 317 326 ?   ?   ?   A . n 
A 1 318 ARG 318 327 ?   ?   ?   A . n 
A 1 319 ARG 319 328 ?   ?   ?   A . n 
A 1 320 LYS 320 329 ?   ?   ?   A . n 
A 1 321 ARG 321 330 ?   ?   ?   A . n 
A 1 322 LYS 322 331 ?   ?   ?   A . n 
A 1 323 ASN 323 332 ?   ?   ?   A . n 
A 1 324 LYS 324 333 ?   ?   ?   A . n 
A 1 325 THR 325 334 ?   ?   ?   A . n 
A 1 326 GLU 326 335 ?   ?   ?   A . n 
A 1 327 ALA 327 336 ?   ?   ?   A . n 
A 1 328 PHE 328 337 ?   ?   ?   A . n 
A 1 329 ASP 329 338 ?   ?   ?   A . n 
A 1 330 MET 330 339 ?   ?   ?   A . n 
A 1 331 ASP 331 340 ?   ?   ?   A . n 
A 1 332 ASP 332 341 ?   ?   ?   A . n 
A 1 333 GLU 333 342 ?   ?   ?   A . n 
A 1 334 VAL 334 343 ?   ?   ?   A . n 
A 1 335 ARG 335 344 ?   ?   ?   A . n 
A 1 336 GLU 336 345 ?   ?   ?   A . n 
A 1 337 GLU 337 346 ?   ?   ?   A . n 
A 1 338 ARG 338 347 ?   ?   ?   A . n 
A 1 339 PHE 339 348 ?   ?   ?   A . n 
A 1 340 SER 340 349 ?   ?   ?   A . n 
A 1 341 PHE 341 350 ?   ?   ?   A . n 
A 1 342 THR 342 351 ?   ?   ?   A . n 
A 1 343 ALA 343 352 ?   ?   ?   A . n 
A 1 344 TYR 344 353 ?   ?   ?   A . n 
A 1 345 GLY 345 354 ?   ?   ?   A . n 
A 1 346 MET 346 355 ?   ?   ?   A . n 
A 1 347 GLY 347 356 ?   ?   ?   A . n 
A 1 348 PRO 348 357 ?   ?   ?   A . n 
A 1 349 CYS 349 358 ?   ?   ?   A . n 
A 1 350 LEU 350 359 ?   ?   ?   A . n 
A 1 351 GLN 351 360 ?   ?   ?   A . n 
A 1 352 ALA 352 361 ?   ?   ?   A . n 
A 1 353 LYS 353 362 ?   ?   ?   A . n 
A 1 354 ASP 354 363 ?   ?   ?   A . n 
A 1 355 GLY 355 364 ?   ?   ?   A . n 
A 1 356 MET 356 365 ?   ?   ?   A . n 
A 1 357 THR 357 366 ?   ?   ?   A . n 
A 1 358 PRO 358 367 ?   ?   ?   A . n 
A 1 359 LYS 359 368 ?   ?   ?   A . n 
A 1 360 GLY 360 369 ?   ?   ?   A . n 
A 1 361 PRO 361 370 ?   ?   ?   A . n 
A 1 362 ASN 362 371 ?   ?   ?   A . n 
A 1 363 HIS 363 372 ?   ?   ?   A . n 
A 1 364 PRO 364 373 ?   ?   ?   A . n 
A 1 365 VAL 365 374 ?   ?   ?   A . n 
A 1 366 GLN 366 375 ?   ?   ?   A . n 
A 1 367 VAL 367 376 ?   ?   ?   A . n 
A 1 368 MET 368 377 ?   ?   ?   A . n 
A 1 369 PRO 369 378 ?   ?   ?   A . n 
A 1 370 LYS 370 379 ?   ?   ?   A . n 
A 1 371 SER 371 380 ?   ?   ?   A . n 
A 1 372 PRO 372 381 ?   ?   ?   A . n 
A 1 373 ASP 373 382 ?   ?   ?   A . n 
A 1 374 GLU 374 383 ?   ?   ?   A . n 
A 1 375 MET 375 384 ?   ?   ?   A . n 
A 1 376 ARG 376 385 ?   ?   ?   A . n 
A 1 377 LYS 377 386 386 LYS LYS A . n 
A 1 378 VAL 378 387 387 VAL VAL A . n 
A 1 379 PHE 379 388 388 PHE PHE A . n 
A 1 380 ILE 380 389 389 ILE ILE A . n 
A 1 381 ASP 381 390 390 ASP ASP A . n 
A 1 382 ARG 382 391 391 ARG ARG A . n 
A 1 383 ALA 383 392 392 ALA ALA A . n 
A 1 384 LYS 384 393 393 LYS LYS A . n 
A 1 385 LYS 385 394 394 LYS LYS A . n 
A 1 386 ILE 386 395 395 ILE ILE A . n 
A 1 387 ASP 387 396 396 ASP ASP A . n 
A 1 388 THR 388 397 397 THR THR A . n 
A 1 389 ILE 389 398 398 ILE ILE A . n 
A 1 390 SER 390 399 399 SER SER A . n 
A 1 391 ARG 391 400 400 ARG ARG A . n 
A 1 392 ALA 392 401 401 ALA ALA A . n 
A 1 393 CYS 393 402 402 CYS CYS A . n 
A 1 394 PHE 394 403 403 PHE PHE A . n 
A 1 395 PRO 395 404 404 PRO PRO A . n 
A 1 396 LEU 396 405 405 LEU LEU A . n 
A 1 397 ALA 397 406 406 ALA ALA A . n 
A 1 398 PHE 398 407 407 PHE PHE A . n 
A 1 399 LEU 399 408 408 LEU LEU A . n 
A 1 400 ILE 400 409 409 ILE ILE A . n 
A 1 401 PHE 401 410 410 PHE PHE A . n 
A 1 402 ASN 402 411 411 ASN ASN A . n 
A 1 403 ILE 403 412 412 ILE ILE A . n 
A 1 404 PHE 404 413 413 PHE PHE A . n 
A 1 405 TYR 405 414 414 TYR TYR A . n 
A 1 406 TRP 406 415 415 TRP TRP A . n 
A 1 407 VAL 407 416 416 VAL VAL A . n 
A 1 408 ILE 408 417 417 ILE ILE A . n 
A 1 409 TYR 409 418 418 TYR TYR A . n 
A 1 410 LYS 410 419 419 LYS LYS A . n 
A 1 411 ILE 411 420 420 ILE ILE A . n 
A 1 412 LEU 412 421 421 LEU LEU A . n 
A 1 413 ARG 413 422 422 ARG ARG A . n 
A 1 414 HIS 414 423 423 HIS HIS A . n 
A 1 415 GLU 415 424 424 GLU GLU A . n 
A 1 416 ASP 416 425 ?   ?   ?   A . n 
A 1 417 ILE 417 426 ?   ?   ?   A . n 
A 1 418 HIS 418 427 ?   ?   ?   A . n 
A 1 419 GLN 419 428 ?   ?   ?   A . n 
A 1 420 GLN 420 429 ?   ?   ?   A . n 
A 1 421 GLN 421 430 ?   ?   ?   A . n 
A 1 422 ASP 422 431 ?   ?   ?   A . n 
B 1 1   ALA 1   1   ?   ?   ?   B . n 
B 1 2   ARG 2   2   ?   ?   ?   B . n 
B 1 3   SER 3   3   ?   ?   ?   B . n 
B 1 4   ARG 4   4   ?   ?   ?   B . n 
B 1 5   SER 5   5   ?   ?   ?   B . n 
B 1 6   ALA 6   6   ?   ?   ?   B . n 
B 1 7   PRO 7   7   ?   ?   ?   B . n 
B 1 8   MET 8   8   8   MET MET B . n 
B 1 9   SER 9   9   9   SER SER B . n 
B 1 10  PRO 10  10  10  PRO PRO B . n 
B 1 11  SER 11  11  11  SER SER B . n 
B 1 12  ASP 12  12  12  ASP ASP B . n 
B 1 13  PHE 13  13  13  PHE PHE B . n 
B 1 14  LEU 14  14  14  LEU LEU B . n 
B 1 15  ASP 15  15  15  ASP ASP B . n 
B 1 16  LYS 16  16  16  LYS LYS B . n 
B 1 17  LEU 17  17  17  LEU LEU B . n 
B 1 18  MET 18  18  18  MET MET B . n 
B 1 19  GLY 19  19  19  GLY GLY B . n 
B 1 20  ARG 20  20  20  ARG ARG B . n 
B 1 21  THR 21  21  21  THR THR B . n 
B 1 22  SER 22  22  22  SER SER B . n 
B 1 23  GLY 23  23  23  GLY GLY B . n 
B 1 24  TYR 24  24  24  TYR TYR B . n 
B 1 25  ASP 25  25  25  ASP ASP B . n 
B 1 26  ALA 26  26  26  ALA ALA B . n 
B 1 27  ARG 27  27  27  ARG ARG B . n 
B 1 28  ILE 28  28  28  ILE ILE B . n 
B 1 29  ARG 29  29  29  ARG ARG B . n 
B 1 30  PRO 30  30  30  PRO PRO B . n 
B 1 31  ASN 31  31  31  ASN ASN B . n 
B 1 32  PHE 32  32  32  PHE PHE B . n 
B 1 33  LYS 33  33  33  LYS LYS B . n 
B 1 34  GLY 34  34  34  GLY GLY B . n 
B 1 35  PRO 35  35  35  PRO PRO B . n 
B 1 36  PRO 36  36  36  PRO PRO B . n 
B 1 37  VAL 37  37  37  VAL VAL B . n 
B 1 38  ASN 38  38  38  ASN ASN B . n 
B 1 39  VAL 39  39  39  VAL VAL B . n 
B 1 40  THR 40  40  40  THR THR B . n 
B 1 41  CYS 41  41  41  CYS CYS B . n 
B 1 42  ASN 42  42  42  ASN ASN B . n 
B 1 43  ILE 43  43  43  ILE ILE B . n 
B 1 44  PHE 44  44  44  PHE PHE B . n 
B 1 45  ILE 45  45  45  ILE ILE B . n 
B 1 46  ASN 46  46  46  ASN ASN B . n 
B 1 47  SER 47  47  47  SER SER B . n 
B 1 48  PHE 48  48  48  PHE PHE B . n 
B 1 49  GLY 49  49  49  GLY GLY B . n 
B 1 50  SER 50  50  50  SER SER B . n 
B 1 51  ILE 51  51  51  ILE ILE B . n 
B 1 52  ALA 52  52  52  ALA ALA B . n 
B 1 53  GLU 53  53  53  GLU GLU B . n 
B 1 54  THR 54  54  54  THR THR B . n 
B 1 55  THR 55  55  55  THR THR B . n 
B 1 56  MET 56  56  56  MET MET B . n 
B 1 57  ASP 57  57  57  ASP ASP B . n 
B 1 58  TYR 58  58  58  TYR TYR B . n 
B 1 59  ARG 59  59  59  ARG ARG B . n 
B 1 60  VAL 60  60  60  VAL VAL B . n 
B 1 61  ASN 61  61  61  ASN ASN B . n 
B 1 62  ILE 62  62  62  ILE ILE B . n 
B 1 63  PHE 63  63  63  PHE PHE B . n 
B 1 64  LEU 64  64  64  LEU LEU B . n 
B 1 65  ARG 65  65  65  ARG ARG B . n 
B 1 66  GLN 66  66  66  GLN GLN B . n 
B 1 67  LYS 67  67  67  LYS LYS B . n 
B 1 68  TRP 68  68  68  TRP TRP B . n 
B 1 69  ASN 69  69  69  ASN ASN B . n 
B 1 70  ASP 70  70  70  ASP ASP B . n 
B 1 71  PRO 71  71  71  PRO PRO B . n 
B 1 72  ARG 72  72  72  ARG ARG B . n 
B 1 73  LEU 73  73  73  LEU LEU B . n 
B 1 74  ALA 74  74  74  ALA ALA B . n 
B 1 75  TYR 75  75  75  TYR TYR B . n 
B 1 76  SER 76  76  76  SER SER B . n 
B 1 77  GLU 77  77  77  GLU GLU B . n 
B 1 78  TYR 78  78  78  TYR TYR B . n 
B 1 79  PRO 79  79  79  PRO PRO B . n 
B 1 80  ASP 80  80  80  ASP ASP B . n 
B 1 81  ASP 81  81  81  ASP ASP B . n 
B 1 82  SER 82  82  82  SER SER B . n 
B 1 83  LEU 83  83  83  LEU LEU B . n 
B 1 84  ASP 84  84  84  ASP ASP B . n 
B 1 85  LEU 85  85  85  LEU LEU B . n 
B 1 86  ASP 86  86  86  ASP ASP B . n 
B 1 87  PRO 87  87  87  PRO PRO B . n 
B 1 88  SER 88  88  88  SER SER B . n 
B 1 89  MET 89  89  89  MET MET B . n 
B 1 90  LEU 90  90  90  LEU LEU B . n 
B 1 91  ASP 91  91  91  ASP ASP B . n 
B 1 92  SER 92  92  92  SER SER B . n 
B 1 93  ILE 93  93  93  ILE ILE B . n 
B 1 94  TRP 94  94  94  TRP TRP B . n 
B 1 95  LYS 95  95  95  LYS LYS B . n 
B 1 96  PRO 96  96  96  PRO PRO B . n 
B 1 97  ASP 97  97  97  ASP ASP B . n 
B 1 98  LEU 98  98  98  LEU LEU B . n 
B 1 99  PHE 99  99  99  PHE PHE B . n 
B 1 100 PHE 100 100 100 PHE PHE B . n 
B 1 101 ALA 101 101 101 ALA ALA B . n 
B 1 102 ASN 102 102 102 ASN ASN B . n 
B 1 103 GLU 103 103 103 GLU GLU B . n 
B 1 104 LYS 104 104 104 LYS LYS B . n 
B 1 105 GLY 105 105 105 GLY GLY B . n 
B 1 106 ALA 106 106 106 ALA ALA B . n 
B 1 107 ASN 107 107 107 ASN ASN B . n 
B 1 108 PHE 108 108 108 PHE PHE B . n 
B 1 109 HIS 109 109 109 HIS HIS B . n 
B 1 110 GLU 110 110 110 GLU GLU B . n 
B 1 111 VAL 111 111 111 VAL VAL B . n 
B 1 112 THR 112 112 112 THR THR B . n 
B 1 113 THR 113 113 113 THR THR B . n 
B 1 114 ASP 114 114 114 ASP ASP B . n 
B 1 115 ASN 115 115 115 ASN ASN B . n 
B 1 116 LYS 116 116 116 LYS LYS B . n 
B 1 117 LEU 117 117 117 LEU LEU B . n 
B 1 118 LEU 118 118 118 LEU LEU B . n 
B 1 119 ARG 119 119 119 ARG ARG B . n 
B 1 120 ILE 120 120 120 ILE ILE B . n 
B 1 121 PHE 121 121 121 PHE PHE B . n 
B 1 122 LYS 122 122 122 LYS LYS B . n 
B 1 123 ASN 123 123 123 ASN ASN B . n 
B 1 124 GLY 124 124 124 GLY GLY B . n 
B 1 125 ASN 125 125 125 ASN ASN B . n 
B 1 126 VAL 126 126 126 VAL VAL B . n 
B 1 127 LEU 127 127 127 LEU LEU B . n 
B 1 128 TYR 128 128 128 TYR TYR B . n 
B 1 129 SER 129 129 129 SER SER B . n 
B 1 130 ILE 130 130 130 ILE ILE B . n 
B 1 131 ARG 131 131 131 ARG ARG B . n 
B 1 132 LEU 132 132 132 LEU LEU B . n 
B 1 133 THR 133 133 133 THR THR B . n 
B 1 134 LEU 134 134 134 LEU LEU B . n 
B 1 135 THR 135 135 135 THR THR B . n 
B 1 136 LEU 136 136 136 LEU LEU B . n 
B 1 137 SER 137 137 137 SER SER B . n 
B 1 138 CYS 138 138 138 CYS CYS B . n 
B 1 139 PRO 139 139 139 PRO PRO B . n 
B 1 140 MET 140 140 140 MET MET B . n 
B 1 141 ASP 141 141 141 ASP ASP B . n 
B 1 142 LEU 142 142 142 LEU LEU B . n 
B 1 143 LYS 143 143 143 LYS LYS B . n 
B 1 144 ASN 144 144 144 ASN ASN B . n 
B 1 145 PHE 145 145 145 PHE PHE B . n 
B 1 146 PRO 146 146 146 PRO PRO B . n 
B 1 147 MET 147 147 147 MET MET B . n 
B 1 148 ASP 148 148 148 ASP ASP B . n 
B 1 149 VAL 149 149 149 VAL VAL B . n 
B 1 150 GLN 150 150 150 GLN GLN B . n 
B 1 151 THR 151 151 151 THR THR B . n 
B 1 152 CYS 152 152 152 CYS CYS B . n 
B 1 153 ILE 153 153 153 ILE ILE B . n 
B 1 154 MET 154 154 154 MET MET B . n 
B 1 155 GLN 155 155 155 GLN GLN B . n 
B 1 156 LEU 156 156 156 LEU LEU B . n 
B 1 157 GLU 157 157 157 GLU GLU B . n 
B 1 158 SER 158 158 158 SER SER B . n 
B 1 159 PHE 159 159 159 PHE PHE B . n 
B 1 160 GLY 160 160 160 GLY GLY B . n 
B 1 161 TYR 161 161 161 TYR TYR B . n 
B 1 162 THR 162 162 162 THR THR B . n 
B 1 163 MET 163 163 163 MET MET B . n 
B 1 164 ASN 164 164 164 ASN ASN B . n 
B 1 165 ASP 165 165 165 ASP ASP B . n 
B 1 166 LEU 166 166 166 LEU LEU B . n 
B 1 167 ILE 167 167 167 ILE ILE B . n 
B 1 168 PHE 168 168 168 PHE PHE B . n 
B 1 169 GLU 169 169 169 GLU GLU B . n 
B 1 170 TRP 170 170 170 TRP TRP B . n 
B 1 171 GLN 171 171 171 GLN GLN B . n 
B 1 172 ASP 172 172 172 ASP ASP B . n 
B 1 173 GLU 173 173 173 GLU GLU B . n 
B 1 174 ALA 174 174 174 ALA ALA B . n 
B 1 175 PRO 175 175 175 PRO PRO B . n 
B 1 176 VAL 176 176 176 VAL VAL B . n 
B 1 177 GLN 177 177 177 GLN GLN B . n 
B 1 178 VAL 178 178 178 VAL VAL B . n 
B 1 179 ALA 179 179 179 ALA ALA B . n 
B 1 180 GLU 180 180 180 GLU GLU B . n 
B 1 181 GLY 181 181 181 GLY GLY B . n 
B 1 182 LEU 182 182 182 LEU LEU B . n 
B 1 183 THR 183 183 183 THR THR B . n 
B 1 184 LEU 184 184 184 LEU LEU B . n 
B 1 185 PRO 185 185 185 PRO PRO B . n 
B 1 186 GLN 186 186 186 GLN GLN B . n 
B 1 187 PHE 187 187 187 PHE PHE B . n 
B 1 188 LEU 188 188 188 LEU LEU B . n 
B 1 189 LEU 189 189 189 LEU LEU B . n 
B 1 190 LYS 190 190 190 LYS LYS B . n 
B 1 191 GLU 191 191 191 GLU GLU B . n 
B 1 192 GLU 192 192 192 GLU GLU B . n 
B 1 193 LYS 193 193 193 LYS LYS B . n 
B 1 194 ASP 194 194 194 ASP ASP B . n 
B 1 195 LEU 195 195 195 LEU LEU B . n 
B 1 196 ARG 196 196 196 ARG ARG B . n 
B 1 197 TYR 197 197 197 TYR TYR B . n 
B 1 198 CYS 198 198 198 CYS CYS B . n 
B 1 199 THR 199 199 199 THR THR B . n 
B 1 200 LYS 200 200 200 LYS LYS B . n 
B 1 201 HIS 201 201 201 HIS HIS B . n 
B 1 202 TYR 202 202 202 TYR TYR B . n 
B 1 203 ASN 203 203 203 ASN ASN B . n 
B 1 204 THR 204 204 204 THR THR B . n 
B 1 205 GLY 205 205 205 GLY GLY B . n 
B 1 206 LYS 206 206 206 LYS LYS B . n 
B 1 207 PHE 207 207 207 PHE PHE B . n 
B 1 208 THR 208 208 208 THR THR B . n 
B 1 209 CYS 209 209 209 CYS CYS B . n 
B 1 210 ILE 210 210 210 ILE ILE B . n 
B 1 211 GLU 211 211 211 GLU GLU B . n 
B 1 212 VAL 212 212 212 VAL VAL B . n 
B 1 213 ARG 213 213 213 ARG ARG B . n 
B 1 214 PHE 214 214 214 PHE PHE B . n 
B 1 215 HIS 215 215 215 HIS HIS B . n 
B 1 216 LEU 216 216 216 LEU LEU B . n 
B 1 217 GLU 217 217 217 GLU GLU B . n 
B 1 218 ARG 218 218 218 ARG ARG B . n 
B 1 219 GLN 219 219 219 GLN GLN B . n 
B 1 220 MET 220 220 220 MET MET B . n 
B 1 221 GLY 221 221 221 GLY GLY B . n 
B 1 222 TYR 222 222 222 TYR TYR B . n 
B 1 223 TYR 223 223 223 TYR TYR B . n 
B 1 224 LEU 224 224 224 LEU LEU B . n 
B 1 225 ILE 225 225 225 ILE ILE B . n 
B 1 226 GLN 226 226 226 GLN GLN B . n 
B 1 227 MET 227 227 227 MET MET B . n 
B 1 228 TYR 228 228 228 TYR TYR B . n 
B 1 229 ILE 229 229 229 ILE ILE B . n 
B 1 230 PRO 230 230 230 PRO PRO B . n 
B 1 231 SER 231 231 231 SER SER B . n 
B 1 232 LEU 232 232 232 LEU LEU B . n 
B 1 233 LEU 233 233 233 LEU LEU B . n 
B 1 234 ILE 234 234 234 ILE ILE B . n 
B 1 235 VAL 235 235 235 VAL VAL B . n 
B 1 236 ILE 236 236 236 ILE ILE B . n 
B 1 237 LEU 237 237 237 LEU LEU B . n 
B 1 238 SER 238 238 238 SER SER B . n 
B 1 239 TRP 239 239 239 TRP TRP B . n 
B 1 240 VAL 240 240 240 VAL VAL B . n 
B 1 241 SER 241 241 241 SER SER B . n 
B 1 242 PHE 242 242 242 PHE PHE B . n 
B 1 243 TRP 243 243 243 TRP TRP B . n 
B 1 244 ILE 244 244 244 ILE ILE B . n 
B 1 245 ASN 245 245 245 ASN ASN B . n 
B 1 246 MET 246 246 246 MET MET B . n 
B 1 247 ASP 247 247 247 ASP ASP B . n 
B 1 248 ALA 248 248 248 ALA ALA B . n 
B 1 249 ALA 249 249 249 ALA ALA B . n 
B 1 250 PRO 250 250 250 PRO PRO B . n 
B 1 251 ALA 251 251 251 ALA ALA B . n 
B 1 252 ARG 252 252 252 ARG ARG B . n 
B 1 253 VAL 253 253 253 VAL VAL B . n 
B 1 254 ALA 254 254 254 ALA ALA B . n 
B 1 255 LEU 255 255 255 LEU LEU B . n 
B 1 256 GLY 256 256 256 GLY GLY B . n 
B 1 257 ILE 257 257 257 ILE ILE B . n 
B 1 258 THR 258 258 258 THR THR B . n 
B 1 259 THR 259 259 259 THR THR B . n 
B 1 260 VAL 260 260 260 VAL VAL B . n 
B 1 261 LEU 261 261 261 LEU LEU B . n 
B 1 262 THR 262 262 262 THR THR B . n 
B 1 263 MET 263 263 263 MET MET B . n 
B 1 264 THR 264 264 264 THR THR B . n 
B 1 265 THR 265 265 265 THR THR B . n 
B 1 266 GLN 266 266 266 GLN GLN B . n 
B 1 267 SER 267 267 267 SER SER B . n 
B 1 268 SER 268 268 268 SER SER B . n 
B 1 269 GLY 269 269 269 GLY GLY B . n 
B 1 270 SER 270 270 270 SER SER B . n 
B 1 271 ARG 271 271 271 ARG ARG B . n 
B 1 272 ALA 272 272 272 ALA ALA B . n 
B 1 273 SER 273 273 273 SER SER B . n 
B 1 274 LEU 274 274 274 LEU LEU B . n 
B 1 275 PRO 275 275 275 PRO PRO B . n 
B 1 276 LYS 276 276 276 LYS LYS B . n 
B 1 277 VAL 277 277 277 VAL VAL B . n 
B 1 278 SER 278 278 278 SER SER B . n 
B 1 279 TYR 279 279 279 TYR TYR B . n 
B 1 280 VAL 280 280 280 VAL VAL B . n 
B 1 281 LYS 281 281 281 LYS LYS B . n 
B 1 282 ALA 282 282 282 ALA ALA B . n 
B 1 283 ILE 283 283 283 ILE ILE B . n 
B 1 284 ASP 284 284 284 ASP ASP B . n 
B 1 285 ILE 285 285 285 ILE ILE B . n 
B 1 286 TRP 286 286 286 TRP TRP B . n 
B 1 287 MET 287 287 287 MET MET B . n 
B 1 288 ALA 288 288 288 ALA ALA B . n 
B 1 289 VAL 289 289 289 VAL VAL B . n 
B 1 290 CYS 290 290 290 CYS CYS B . n 
B 1 291 LEU 291 291 291 LEU LEU B . n 
B 1 292 LEU 292 292 292 LEU LEU B . n 
B 1 293 PHE 293 293 293 PHE PHE B . n 
B 1 294 VAL 294 294 294 VAL VAL B . n 
B 1 295 PHE 295 295 295 PHE PHE B . n 
B 1 296 SER 296 296 296 SER SER B . n 
B 1 297 ALA 297 297 297 ALA ALA B . n 
B 1 298 LEU 298 298 298 LEU LEU B . n 
B 1 299 LEU 299 299 299 LEU LEU B . n 
B 1 300 GLU 300 300 300 GLU GLU B . n 
B 1 301 TYR 301 301 301 TYR TYR B . n 
B 1 302 ALA 302 302 302 ALA ALA B . n 
B 1 303 ALA 303 303 303 ALA ALA B . n 
B 1 304 VAL 304 304 304 VAL VAL B . n 
B 1 305 ASN 305 305 305 ASN ASN B . n 
B 1 306 PHE 306 306 306 PHE PHE B . n 
B 1 307 VAL 307 307 307 VAL VAL B . n 
B 1 308 SER 308 308 308 SER SER B . n 
B 1 309 ARG 309 309 309 ARG ARG B . n 
B 1 310 GLN 310 310 310 GLN GLN B . n 
B 1 311 HIS 311 320 ?   ?   ?   B . n 
B 1 312 LYS 312 321 ?   ?   ?   B . n 
B 1 313 GLU 313 322 ?   ?   ?   B . n 
B 1 314 LEU 314 323 ?   ?   ?   B . n 
B 1 315 LEU 315 324 ?   ?   ?   B . n 
B 1 316 ARG 316 325 ?   ?   ?   B . n 
B 1 317 PHE 317 326 ?   ?   ?   B . n 
B 1 318 ARG 318 327 ?   ?   ?   B . n 
B 1 319 ARG 319 328 ?   ?   ?   B . n 
B 1 320 LYS 320 329 ?   ?   ?   B . n 
B 1 321 ARG 321 330 ?   ?   ?   B . n 
B 1 322 LYS 322 331 ?   ?   ?   B . n 
B 1 323 ASN 323 332 ?   ?   ?   B . n 
B 1 324 LYS 324 333 ?   ?   ?   B . n 
B 1 325 THR 325 334 ?   ?   ?   B . n 
B 1 326 GLU 326 335 ?   ?   ?   B . n 
B 1 327 ALA 327 336 ?   ?   ?   B . n 
B 1 328 PHE 328 337 ?   ?   ?   B . n 
B 1 329 ASP 329 338 ?   ?   ?   B . n 
B 1 330 MET 330 339 ?   ?   ?   B . n 
B 1 331 ASP 331 340 ?   ?   ?   B . n 
B 1 332 ASP 332 341 ?   ?   ?   B . n 
B 1 333 GLU 333 342 ?   ?   ?   B . n 
B 1 334 VAL 334 343 ?   ?   ?   B . n 
B 1 335 ARG 335 344 ?   ?   ?   B . n 
B 1 336 GLU 336 345 ?   ?   ?   B . n 
B 1 337 GLU 337 346 ?   ?   ?   B . n 
B 1 338 ARG 338 347 ?   ?   ?   B . n 
B 1 339 PHE 339 348 ?   ?   ?   B . n 
B 1 340 SER 340 349 ?   ?   ?   B . n 
B 1 341 PHE 341 350 ?   ?   ?   B . n 
B 1 342 THR 342 351 ?   ?   ?   B . n 
B 1 343 ALA 343 352 ?   ?   ?   B . n 
B 1 344 TYR 344 353 ?   ?   ?   B . n 
B 1 345 GLY 345 354 ?   ?   ?   B . n 
B 1 346 MET 346 355 ?   ?   ?   B . n 
B 1 347 GLY 347 356 ?   ?   ?   B . n 
B 1 348 PRO 348 357 ?   ?   ?   B . n 
B 1 349 CYS 349 358 ?   ?   ?   B . n 
B 1 350 LEU 350 359 ?   ?   ?   B . n 
B 1 351 GLN 351 360 ?   ?   ?   B . n 
B 1 352 ALA 352 361 ?   ?   ?   B . n 
B 1 353 LYS 353 362 ?   ?   ?   B . n 
B 1 354 ASP 354 363 ?   ?   ?   B . n 
B 1 355 GLY 355 364 ?   ?   ?   B . n 
B 1 356 MET 356 365 ?   ?   ?   B . n 
B 1 357 THR 357 366 ?   ?   ?   B . n 
B 1 358 PRO 358 367 ?   ?   ?   B . n 
B 1 359 LYS 359 368 ?   ?   ?   B . n 
B 1 360 GLY 360 369 ?   ?   ?   B . n 
B 1 361 PRO 361 370 ?   ?   ?   B . n 
B 1 362 ASN 362 371 ?   ?   ?   B . n 
B 1 363 HIS 363 372 ?   ?   ?   B . n 
B 1 364 PRO 364 373 ?   ?   ?   B . n 
B 1 365 VAL 365 374 ?   ?   ?   B . n 
B 1 366 GLN 366 375 ?   ?   ?   B . n 
B 1 367 VAL 367 376 ?   ?   ?   B . n 
B 1 368 MET 368 377 ?   ?   ?   B . n 
B 1 369 PRO 369 378 ?   ?   ?   B . n 
B 1 370 LYS 370 379 ?   ?   ?   B . n 
B 1 371 SER 371 380 ?   ?   ?   B . n 
B 1 372 PRO 372 381 ?   ?   ?   B . n 
B 1 373 ASP 373 382 ?   ?   ?   B . n 
B 1 374 GLU 374 383 ?   ?   ?   B . n 
B 1 375 MET 375 384 ?   ?   ?   B . n 
B 1 376 ARG 376 385 385 ARG ARG B . n 
B 1 377 LYS 377 386 386 LYS LYS B . n 
B 1 378 VAL 378 387 387 VAL VAL B . n 
B 1 379 PHE 379 388 388 PHE PHE B . n 
B 1 380 ILE 380 389 389 ILE ILE B . n 
B 1 381 ASP 381 390 390 ASP ASP B . n 
B 1 382 ARG 382 391 391 ARG ARG B . n 
B 1 383 ALA 383 392 392 ALA ALA B . n 
B 1 384 LYS 384 393 393 LYS LYS B . n 
B 1 385 LYS 385 394 394 LYS LYS B . n 
B 1 386 ILE 386 395 395 ILE ILE B . n 
B 1 387 ASP 387 396 396 ASP ASP B . n 
B 1 388 THR 388 397 397 THR THR B . n 
B 1 389 ILE 389 398 398 ILE ILE B . n 
B 1 390 SER 390 399 399 SER SER B . n 
B 1 391 ARG 391 400 400 ARG ARG B . n 
B 1 392 ALA 392 401 401 ALA ALA B . n 
B 1 393 CYS 393 402 402 CYS CYS B . n 
B 1 394 PHE 394 403 403 PHE PHE B . n 
B 1 395 PRO 395 404 404 PRO PRO B . n 
B 1 396 LEU 396 405 405 LEU LEU B . n 
B 1 397 ALA 397 406 406 ALA ALA B . n 
B 1 398 PHE 398 407 407 PHE PHE B . n 
B 1 399 LEU 399 408 408 LEU LEU B . n 
B 1 400 ILE 400 409 409 ILE ILE B . n 
B 1 401 PHE 401 410 410 PHE PHE B . n 
B 1 402 ASN 402 411 411 ASN ASN B . n 
B 1 403 ILE 403 412 412 ILE ILE B . n 
B 1 404 PHE 404 413 413 PHE PHE B . n 
B 1 405 TYR 405 414 414 TYR TYR B . n 
B 1 406 TRP 406 415 415 TRP TRP B . n 
B 1 407 VAL 407 416 416 VAL VAL B . n 
B 1 408 ILE 408 417 417 ILE ILE B . n 
B 1 409 TYR 409 418 418 TYR TYR B . n 
B 1 410 LYS 410 419 419 LYS LYS B . n 
B 1 411 ILE 411 420 420 ILE ILE B . n 
B 1 412 LEU 412 421 421 LEU LEU B . n 
B 1 413 ARG 413 422 422 ARG ARG B . n 
B 1 414 HIS 414 423 ?   ?   ?   B . n 
B 1 415 GLU 415 424 ?   ?   ?   B . n 
B 1 416 ASP 416 425 ?   ?   ?   B . n 
B 1 417 ILE 417 426 ?   ?   ?   B . n 
B 1 418 HIS 418 427 ?   ?   ?   B . n 
B 1 419 GLN 419 428 ?   ?   ?   B . n 
B 1 420 GLN 420 429 ?   ?   ?   B . n 
B 1 421 GLN 421 430 ?   ?   ?   B . n 
B 1 422 ASP 422 431 ?   ?   ?   B . n 
C 1 1   ALA 1   1   ?   ?   ?   C . n 
C 1 2   ARG 2   2   ?   ?   ?   C . n 
C 1 3   SER 3   3   ?   ?   ?   C . n 
C 1 4   ARG 4   4   ?   ?   ?   C . n 
C 1 5   SER 5   5   ?   ?   ?   C . n 
C 1 6   ALA 6   6   ?   ?   ?   C . n 
C 1 7   PRO 7   7   ?   ?   ?   C . n 
C 1 8   MET 8   8   8   MET MET C . n 
C 1 9   SER 9   9   9   SER SER C . n 
C 1 10  PRO 10  10  10  PRO PRO C . n 
C 1 11  SER 11  11  11  SER SER C . n 
C 1 12  ASP 12  12  12  ASP ASP C . n 
C 1 13  PHE 13  13  13  PHE PHE C . n 
C 1 14  LEU 14  14  14  LEU LEU C . n 
C 1 15  ASP 15  15  15  ASP ASP C . n 
C 1 16  LYS 16  16  16  LYS LYS C . n 
C 1 17  LEU 17  17  17  LEU LEU C . n 
C 1 18  MET 18  18  18  MET MET C . n 
C 1 19  GLY 19  19  19  GLY GLY C . n 
C 1 20  ARG 20  20  20  ARG ARG C . n 
C 1 21  THR 21  21  21  THR THR C . n 
C 1 22  SER 22  22  22  SER SER C . n 
C 1 23  GLY 23  23  23  GLY GLY C . n 
C 1 24  TYR 24  24  24  TYR TYR C . n 
C 1 25  ASP 25  25  25  ASP ASP C . n 
C 1 26  ALA 26  26  26  ALA ALA C . n 
C 1 27  ARG 27  27  27  ARG ARG C . n 
C 1 28  ILE 28  28  28  ILE ILE C . n 
C 1 29  ARG 29  29  29  ARG ARG C . n 
C 1 30  PRO 30  30  30  PRO PRO C . n 
C 1 31  ASN 31  31  31  ASN ASN C . n 
C 1 32  PHE 32  32  32  PHE PHE C . n 
C 1 33  LYS 33  33  33  LYS LYS C . n 
C 1 34  GLY 34  34  34  GLY GLY C . n 
C 1 35  PRO 35  35  35  PRO PRO C . n 
C 1 36  PRO 36  36  36  PRO PRO C . n 
C 1 37  VAL 37  37  37  VAL VAL C . n 
C 1 38  ASN 38  38  38  ASN ASN C . n 
C 1 39  VAL 39  39  39  VAL VAL C . n 
C 1 40  THR 40  40  40  THR THR C . n 
C 1 41  CYS 41  41  41  CYS CYS C . n 
C 1 42  ASN 42  42  42  ASN ASN C . n 
C 1 43  ILE 43  43  43  ILE ILE C . n 
C 1 44  PHE 44  44  44  PHE PHE C . n 
C 1 45  ILE 45  45  45  ILE ILE C . n 
C 1 46  ASN 46  46  46  ASN ASN C . n 
C 1 47  SER 47  47  47  SER SER C . n 
C 1 48  PHE 48  48  48  PHE PHE C . n 
C 1 49  GLY 49  49  49  GLY GLY C . n 
C 1 50  SER 50  50  50  SER SER C . n 
C 1 51  ILE 51  51  51  ILE ILE C . n 
C 1 52  ALA 52  52  52  ALA ALA C . n 
C 1 53  GLU 53  53  53  GLU GLU C . n 
C 1 54  THR 54  54  54  THR THR C . n 
C 1 55  THR 55  55  55  THR THR C . n 
C 1 56  MET 56  56  56  MET MET C . n 
C 1 57  ASP 57  57  57  ASP ASP C . n 
C 1 58  TYR 58  58  58  TYR TYR C . n 
C 1 59  ARG 59  59  59  ARG ARG C . n 
C 1 60  VAL 60  60  60  VAL VAL C . n 
C 1 61  ASN 61  61  61  ASN ASN C . n 
C 1 62  ILE 62  62  62  ILE ILE C . n 
C 1 63  PHE 63  63  63  PHE PHE C . n 
C 1 64  LEU 64  64  64  LEU LEU C . n 
C 1 65  ARG 65  65  65  ARG ARG C . n 
C 1 66  GLN 66  66  66  GLN GLN C . n 
C 1 67  LYS 67  67  67  LYS LYS C . n 
C 1 68  TRP 68  68  68  TRP TRP C . n 
C 1 69  ASN 69  69  69  ASN ASN C . n 
C 1 70  ASP 70  70  70  ASP ASP C . n 
C 1 71  PRO 71  71  71  PRO PRO C . n 
C 1 72  ARG 72  72  72  ARG ARG C . n 
C 1 73  LEU 73  73  73  LEU LEU C . n 
C 1 74  ALA 74  74  74  ALA ALA C . n 
C 1 75  TYR 75  75  75  TYR TYR C . n 
C 1 76  SER 76  76  76  SER SER C . n 
C 1 77  GLU 77  77  77  GLU GLU C . n 
C 1 78  TYR 78  78  78  TYR TYR C . n 
C 1 79  PRO 79  79  79  PRO PRO C . n 
C 1 80  ASP 80  80  80  ASP ASP C . n 
C 1 81  ASP 81  81  81  ASP ASP C . n 
C 1 82  SER 82  82  82  SER SER C . n 
C 1 83  LEU 83  83  83  LEU LEU C . n 
C 1 84  ASP 84  84  84  ASP ASP C . n 
C 1 85  LEU 85  85  85  LEU LEU C . n 
C 1 86  ASP 86  86  86  ASP ASP C . n 
C 1 87  PRO 87  87  87  PRO PRO C . n 
C 1 88  SER 88  88  88  SER SER C . n 
C 1 89  MET 89  89  89  MET MET C . n 
C 1 90  LEU 90  90  90  LEU LEU C . n 
C 1 91  ASP 91  91  91  ASP ASP C . n 
C 1 92  SER 92  92  92  SER SER C . n 
C 1 93  ILE 93  93  93  ILE ILE C . n 
C 1 94  TRP 94  94  94  TRP TRP C . n 
C 1 95  LYS 95  95  95  LYS LYS C . n 
C 1 96  PRO 96  96  96  PRO PRO C . n 
C 1 97  ASP 97  97  97  ASP ASP C . n 
C 1 98  LEU 98  98  98  LEU LEU C . n 
C 1 99  PHE 99  99  99  PHE PHE C . n 
C 1 100 PHE 100 100 100 PHE PHE C . n 
C 1 101 ALA 101 101 101 ALA ALA C . n 
C 1 102 ASN 102 102 102 ASN ASN C . n 
C 1 103 GLU 103 103 103 GLU GLU C . n 
C 1 104 LYS 104 104 104 LYS LYS C . n 
C 1 105 GLY 105 105 105 GLY GLY C . n 
C 1 106 ALA 106 106 106 ALA ALA C . n 
C 1 107 ASN 107 107 107 ASN ASN C . n 
C 1 108 PHE 108 108 108 PHE PHE C . n 
C 1 109 HIS 109 109 109 HIS HIS C . n 
C 1 110 GLU 110 110 110 GLU GLU C . n 
C 1 111 VAL 111 111 111 VAL VAL C . n 
C 1 112 THR 112 112 112 THR THR C . n 
C 1 113 THR 113 113 113 THR THR C . n 
C 1 114 ASP 114 114 114 ASP ASP C . n 
C 1 115 ASN 115 115 115 ASN ASN C . n 
C 1 116 LYS 116 116 116 LYS LYS C . n 
C 1 117 LEU 117 117 117 LEU LEU C . n 
C 1 118 LEU 118 118 118 LEU LEU C . n 
C 1 119 ARG 119 119 119 ARG ARG C . n 
C 1 120 ILE 120 120 120 ILE ILE C . n 
C 1 121 PHE 121 121 121 PHE PHE C . n 
C 1 122 LYS 122 122 122 LYS LYS C . n 
C 1 123 ASN 123 123 123 ASN ASN C . n 
C 1 124 GLY 124 124 124 GLY GLY C . n 
C 1 125 ASN 125 125 125 ASN ASN C . n 
C 1 126 VAL 126 126 126 VAL VAL C . n 
C 1 127 LEU 127 127 127 LEU LEU C . n 
C 1 128 TYR 128 128 128 TYR TYR C . n 
C 1 129 SER 129 129 129 SER SER C . n 
C 1 130 ILE 130 130 130 ILE ILE C . n 
C 1 131 ARG 131 131 131 ARG ARG C . n 
C 1 132 LEU 132 132 132 LEU LEU C . n 
C 1 133 THR 133 133 133 THR THR C . n 
C 1 134 LEU 134 134 134 LEU LEU C . n 
C 1 135 THR 135 135 135 THR THR C . n 
C 1 136 LEU 136 136 136 LEU LEU C . n 
C 1 137 SER 137 137 137 SER SER C . n 
C 1 138 CYS 138 138 138 CYS CYS C . n 
C 1 139 PRO 139 139 139 PRO PRO C . n 
C 1 140 MET 140 140 140 MET MET C . n 
C 1 141 ASP 141 141 141 ASP ASP C . n 
C 1 142 LEU 142 142 142 LEU LEU C . n 
C 1 143 LYS 143 143 143 LYS LYS C . n 
C 1 144 ASN 144 144 144 ASN ASN C . n 
C 1 145 PHE 145 145 145 PHE PHE C . n 
C 1 146 PRO 146 146 146 PRO PRO C . n 
C 1 147 MET 147 147 147 MET MET C . n 
C 1 148 ASP 148 148 148 ASP ASP C . n 
C 1 149 VAL 149 149 149 VAL VAL C . n 
C 1 150 GLN 150 150 150 GLN GLN C . n 
C 1 151 THR 151 151 151 THR THR C . n 
C 1 152 CYS 152 152 152 CYS CYS C . n 
C 1 153 ILE 153 153 153 ILE ILE C . n 
C 1 154 MET 154 154 154 MET MET C . n 
C 1 155 GLN 155 155 155 GLN GLN C . n 
C 1 156 LEU 156 156 156 LEU LEU C . n 
C 1 157 GLU 157 157 157 GLU GLU C . n 
C 1 158 SER 158 158 158 SER SER C . n 
C 1 159 PHE 159 159 159 PHE PHE C . n 
C 1 160 GLY 160 160 160 GLY GLY C . n 
C 1 161 TYR 161 161 161 TYR TYR C . n 
C 1 162 THR 162 162 162 THR THR C . n 
C 1 163 MET 163 163 163 MET MET C . n 
C 1 164 ASN 164 164 164 ASN ASN C . n 
C 1 165 ASP 165 165 165 ASP ASP C . n 
C 1 166 LEU 166 166 166 LEU LEU C . n 
C 1 167 ILE 167 167 167 ILE ILE C . n 
C 1 168 PHE 168 168 168 PHE PHE C . n 
C 1 169 GLU 169 169 169 GLU GLU C . n 
C 1 170 TRP 170 170 170 TRP TRP C . n 
C 1 171 GLN 171 171 171 GLN GLN C . n 
C 1 172 ASP 172 172 172 ASP ASP C . n 
C 1 173 GLU 173 173 173 GLU GLU C . n 
C 1 174 ALA 174 174 174 ALA ALA C . n 
C 1 175 PRO 175 175 175 PRO PRO C . n 
C 1 176 VAL 176 176 176 VAL VAL C . n 
C 1 177 GLN 177 177 177 GLN GLN C . n 
C 1 178 VAL 178 178 178 VAL VAL C . n 
C 1 179 ALA 179 179 179 ALA ALA C . n 
C 1 180 GLU 180 180 180 GLU GLU C . n 
C 1 181 GLY 181 181 181 GLY GLY C . n 
C 1 182 LEU 182 182 182 LEU LEU C . n 
C 1 183 THR 183 183 183 THR THR C . n 
C 1 184 LEU 184 184 184 LEU LEU C . n 
C 1 185 PRO 185 185 185 PRO PRO C . n 
C 1 186 GLN 186 186 186 GLN GLN C . n 
C 1 187 PHE 187 187 187 PHE PHE C . n 
C 1 188 LEU 188 188 188 LEU LEU C . n 
C 1 189 LEU 189 189 189 LEU LEU C . n 
C 1 190 LYS 190 190 190 LYS LYS C . n 
C 1 191 GLU 191 191 191 GLU GLU C . n 
C 1 192 GLU 192 192 192 GLU GLU C . n 
C 1 193 LYS 193 193 193 LYS LYS C . n 
C 1 194 ASP 194 194 194 ASP ASP C . n 
C 1 195 LEU 195 195 195 LEU LEU C . n 
C 1 196 ARG 196 196 196 ARG ARG C . n 
C 1 197 TYR 197 197 197 TYR TYR C . n 
C 1 198 CYS 198 198 198 CYS CYS C . n 
C 1 199 THR 199 199 199 THR THR C . n 
C 1 200 LYS 200 200 200 LYS LYS C . n 
C 1 201 HIS 201 201 201 HIS HIS C . n 
C 1 202 TYR 202 202 202 TYR TYR C . n 
C 1 203 ASN 203 203 203 ASN ASN C . n 
C 1 204 THR 204 204 204 THR THR C . n 
C 1 205 GLY 205 205 205 GLY GLY C . n 
C 1 206 LYS 206 206 206 LYS LYS C . n 
C 1 207 PHE 207 207 207 PHE PHE C . n 
C 1 208 THR 208 208 208 THR THR C . n 
C 1 209 CYS 209 209 209 CYS CYS C . n 
C 1 210 ILE 210 210 210 ILE ILE C . n 
C 1 211 GLU 211 211 211 GLU GLU C . n 
C 1 212 VAL 212 212 212 VAL VAL C . n 
C 1 213 ARG 213 213 213 ARG ARG C . n 
C 1 214 PHE 214 214 214 PHE PHE C . n 
C 1 215 HIS 215 215 215 HIS HIS C . n 
C 1 216 LEU 216 216 216 LEU LEU C . n 
C 1 217 GLU 217 217 217 GLU GLU C . n 
C 1 218 ARG 218 218 218 ARG ARG C . n 
C 1 219 GLN 219 219 219 GLN GLN C . n 
C 1 220 MET 220 220 220 MET MET C . n 
C 1 221 GLY 221 221 221 GLY GLY C . n 
C 1 222 TYR 222 222 222 TYR TYR C . n 
C 1 223 TYR 223 223 223 TYR TYR C . n 
C 1 224 LEU 224 224 224 LEU LEU C . n 
C 1 225 ILE 225 225 225 ILE ILE C . n 
C 1 226 GLN 226 226 226 GLN GLN C . n 
C 1 227 MET 227 227 227 MET MET C . n 
C 1 228 TYR 228 228 228 TYR TYR C . n 
C 1 229 ILE 229 229 229 ILE ILE C . n 
C 1 230 PRO 230 230 230 PRO PRO C . n 
C 1 231 SER 231 231 231 SER SER C . n 
C 1 232 LEU 232 232 232 LEU LEU C . n 
C 1 233 LEU 233 233 233 LEU LEU C . n 
C 1 234 ILE 234 234 234 ILE ILE C . n 
C 1 235 VAL 235 235 235 VAL VAL C . n 
C 1 236 ILE 236 236 236 ILE ILE C . n 
C 1 237 LEU 237 237 237 LEU LEU C . n 
C 1 238 SER 238 238 238 SER SER C . n 
C 1 239 TRP 239 239 239 TRP TRP C . n 
C 1 240 VAL 240 240 240 VAL VAL C . n 
C 1 241 SER 241 241 241 SER SER C . n 
C 1 242 PHE 242 242 242 PHE PHE C . n 
C 1 243 TRP 243 243 243 TRP TRP C . n 
C 1 244 ILE 244 244 244 ILE ILE C . n 
C 1 245 ASN 245 245 245 ASN ASN C . n 
C 1 246 MET 246 246 246 MET MET C . n 
C 1 247 ASP 247 247 247 ASP ASP C . n 
C 1 248 ALA 248 248 248 ALA ALA C . n 
C 1 249 ALA 249 249 249 ALA ALA C . n 
C 1 250 PRO 250 250 250 PRO PRO C . n 
C 1 251 ALA 251 251 251 ALA ALA C . n 
C 1 252 ARG 252 252 252 ARG ARG C . n 
C 1 253 VAL 253 253 253 VAL VAL C . n 
C 1 254 ALA 254 254 254 ALA ALA C . n 
C 1 255 LEU 255 255 255 LEU LEU C . n 
C 1 256 GLY 256 256 256 GLY GLY C . n 
C 1 257 ILE 257 257 257 ILE ILE C . n 
C 1 258 THR 258 258 258 THR THR C . n 
C 1 259 THR 259 259 259 THR THR C . n 
C 1 260 VAL 260 260 260 VAL VAL C . n 
C 1 261 LEU 261 261 261 LEU LEU C . n 
C 1 262 THR 262 262 262 THR THR C . n 
C 1 263 MET 263 263 263 MET MET C . n 
C 1 264 THR 264 264 264 THR THR C . n 
C 1 265 THR 265 265 265 THR THR C . n 
C 1 266 GLN 266 266 266 GLN GLN C . n 
C 1 267 SER 267 267 267 SER SER C . n 
C 1 268 SER 268 268 268 SER SER C . n 
C 1 269 GLY 269 269 269 GLY GLY C . n 
C 1 270 SER 270 270 270 SER SER C . n 
C 1 271 ARG 271 271 271 ARG ARG C . n 
C 1 272 ALA 272 272 272 ALA ALA C . n 
C 1 273 SER 273 273 273 SER SER C . n 
C 1 274 LEU 274 274 274 LEU LEU C . n 
C 1 275 PRO 275 275 275 PRO PRO C . n 
C 1 276 LYS 276 276 276 LYS LYS C . n 
C 1 277 VAL 277 277 277 VAL VAL C . n 
C 1 278 SER 278 278 278 SER SER C . n 
C 1 279 TYR 279 279 279 TYR TYR C . n 
C 1 280 VAL 280 280 280 VAL VAL C . n 
C 1 281 LYS 281 281 281 LYS LYS C . n 
C 1 282 ALA 282 282 282 ALA ALA C . n 
C 1 283 ILE 283 283 283 ILE ILE C . n 
C 1 284 ASP 284 284 284 ASP ASP C . n 
C 1 285 ILE 285 285 285 ILE ILE C . n 
C 1 286 TRP 286 286 286 TRP TRP C . n 
C 1 287 MET 287 287 287 MET MET C . n 
C 1 288 ALA 288 288 288 ALA ALA C . n 
C 1 289 VAL 289 289 289 VAL VAL C . n 
C 1 290 CYS 290 290 290 CYS CYS C . n 
C 1 291 LEU 291 291 291 LEU LEU C . n 
C 1 292 LEU 292 292 292 LEU LEU C . n 
C 1 293 PHE 293 293 293 PHE PHE C . n 
C 1 294 VAL 294 294 294 VAL VAL C . n 
C 1 295 PHE 295 295 295 PHE PHE C . n 
C 1 296 SER 296 296 296 SER SER C . n 
C 1 297 ALA 297 297 297 ALA ALA C . n 
C 1 298 LEU 298 298 298 LEU LEU C . n 
C 1 299 LEU 299 299 299 LEU LEU C . n 
C 1 300 GLU 300 300 300 GLU GLU C . n 
C 1 301 TYR 301 301 301 TYR TYR C . n 
C 1 302 ALA 302 302 302 ALA ALA C . n 
C 1 303 ALA 303 303 303 ALA ALA C . n 
C 1 304 VAL 304 304 304 VAL VAL C . n 
C 1 305 ASN 305 305 305 ASN ASN C . n 
C 1 306 PHE 306 306 306 PHE PHE C . n 
C 1 307 VAL 307 307 307 VAL VAL C . n 
C 1 308 SER 308 308 308 SER SER C . n 
C 1 309 ARG 309 309 309 ARG ARG C . n 
C 1 310 GLN 310 310 310 GLN GLN C . n 
C 1 311 HIS 311 320 ?   ?   ?   C . n 
C 1 312 LYS 312 321 ?   ?   ?   C . n 
C 1 313 GLU 313 322 ?   ?   ?   C . n 
C 1 314 LEU 314 323 ?   ?   ?   C . n 
C 1 315 LEU 315 324 ?   ?   ?   C . n 
C 1 316 ARG 316 325 ?   ?   ?   C . n 
C 1 317 PHE 317 326 ?   ?   ?   C . n 
C 1 318 ARG 318 327 ?   ?   ?   C . n 
C 1 319 ARG 319 328 ?   ?   ?   C . n 
C 1 320 LYS 320 329 ?   ?   ?   C . n 
C 1 321 ARG 321 330 ?   ?   ?   C . n 
C 1 322 LYS 322 331 ?   ?   ?   C . n 
C 1 323 ASN 323 332 ?   ?   ?   C . n 
C 1 324 LYS 324 333 ?   ?   ?   C . n 
C 1 325 THR 325 334 ?   ?   ?   C . n 
C 1 326 GLU 326 335 ?   ?   ?   C . n 
C 1 327 ALA 327 336 ?   ?   ?   C . n 
C 1 328 PHE 328 337 ?   ?   ?   C . n 
C 1 329 ASP 329 338 ?   ?   ?   C . n 
C 1 330 MET 330 339 ?   ?   ?   C . n 
C 1 331 ASP 331 340 ?   ?   ?   C . n 
C 1 332 ASP 332 341 ?   ?   ?   C . n 
C 1 333 GLU 333 342 ?   ?   ?   C . n 
C 1 334 VAL 334 343 ?   ?   ?   C . n 
C 1 335 ARG 335 344 ?   ?   ?   C . n 
C 1 336 GLU 336 345 ?   ?   ?   C . n 
C 1 337 GLU 337 346 ?   ?   ?   C . n 
C 1 338 ARG 338 347 ?   ?   ?   C . n 
C 1 339 PHE 339 348 ?   ?   ?   C . n 
C 1 340 SER 340 349 ?   ?   ?   C . n 
C 1 341 PHE 341 350 ?   ?   ?   C . n 
C 1 342 THR 342 351 ?   ?   ?   C . n 
C 1 343 ALA 343 352 ?   ?   ?   C . n 
C 1 344 TYR 344 353 ?   ?   ?   C . n 
C 1 345 GLY 345 354 ?   ?   ?   C . n 
C 1 346 MET 346 355 ?   ?   ?   C . n 
C 1 347 GLY 347 356 ?   ?   ?   C . n 
C 1 348 PRO 348 357 ?   ?   ?   C . n 
C 1 349 CYS 349 358 ?   ?   ?   C . n 
C 1 350 LEU 350 359 ?   ?   ?   C . n 
C 1 351 GLN 351 360 ?   ?   ?   C . n 
C 1 352 ALA 352 361 ?   ?   ?   C . n 
C 1 353 LYS 353 362 ?   ?   ?   C . n 
C 1 354 ASP 354 363 ?   ?   ?   C . n 
C 1 355 GLY 355 364 ?   ?   ?   C . n 
C 1 356 MET 356 365 ?   ?   ?   C . n 
C 1 357 THR 357 366 ?   ?   ?   C . n 
C 1 358 PRO 358 367 ?   ?   ?   C . n 
C 1 359 LYS 359 368 ?   ?   ?   C . n 
C 1 360 GLY 360 369 ?   ?   ?   C . n 
C 1 361 PRO 361 370 ?   ?   ?   C . n 
C 1 362 ASN 362 371 ?   ?   ?   C . n 
C 1 363 HIS 363 372 ?   ?   ?   C . n 
C 1 364 PRO 364 373 ?   ?   ?   C . n 
C 1 365 VAL 365 374 ?   ?   ?   C . n 
C 1 366 GLN 366 375 ?   ?   ?   C . n 
C 1 367 VAL 367 376 ?   ?   ?   C . n 
C 1 368 MET 368 377 ?   ?   ?   C . n 
C 1 369 PRO 369 378 ?   ?   ?   C . n 
C 1 370 LYS 370 379 ?   ?   ?   C . n 
C 1 371 SER 371 380 ?   ?   ?   C . n 
C 1 372 PRO 372 381 ?   ?   ?   C . n 
C 1 373 ASP 373 382 ?   ?   ?   C . n 
C 1 374 GLU 374 383 ?   ?   ?   C . n 
C 1 375 MET 375 384 ?   ?   ?   C . n 
C 1 376 ARG 376 385 ?   ?   ?   C . n 
C 1 377 LYS 377 386 386 LYS LYS C . n 
C 1 378 VAL 378 387 387 VAL VAL C . n 
C 1 379 PHE 379 388 388 PHE PHE C . n 
C 1 380 ILE 380 389 389 ILE ILE C . n 
C 1 381 ASP 381 390 390 ASP ASP C . n 
C 1 382 ARG 382 391 391 ARG ARG C . n 
C 1 383 ALA 383 392 392 ALA ALA C . n 
C 1 384 LYS 384 393 393 LYS LYS C . n 
C 1 385 LYS 385 394 394 LYS LYS C . n 
C 1 386 ILE 386 395 395 ILE ILE C . n 
C 1 387 ASP 387 396 396 ASP ASP C . n 
C 1 388 THR 388 397 397 THR THR C . n 
C 1 389 ILE 389 398 398 ILE ILE C . n 
C 1 390 SER 390 399 399 SER SER C . n 
C 1 391 ARG 391 400 400 ARG ARG C . n 
C 1 392 ALA 392 401 401 ALA ALA C . n 
C 1 393 CYS 393 402 402 CYS CYS C . n 
C 1 394 PHE 394 403 403 PHE PHE C . n 
C 1 395 PRO 395 404 404 PRO PRO C . n 
C 1 396 LEU 396 405 405 LEU LEU C . n 
C 1 397 ALA 397 406 406 ALA ALA C . n 
C 1 398 PHE 398 407 407 PHE PHE C . n 
C 1 399 LEU 399 408 408 LEU LEU C . n 
C 1 400 ILE 400 409 409 ILE ILE C . n 
C 1 401 PHE 401 410 410 PHE PHE C . n 
C 1 402 ASN 402 411 411 ASN ASN C . n 
C 1 403 ILE 403 412 412 ILE ILE C . n 
C 1 404 PHE 404 413 413 PHE PHE C . n 
C 1 405 TYR 405 414 414 TYR TYR C . n 
C 1 406 TRP 406 415 415 TRP TRP C . n 
C 1 407 VAL 407 416 416 VAL VAL C . n 
C 1 408 ILE 408 417 417 ILE ILE C . n 
C 1 409 TYR 409 418 418 TYR TYR C . n 
C 1 410 LYS 410 419 419 LYS LYS C . n 
C 1 411 ILE 411 420 420 ILE ILE C . n 
C 1 412 LEU 412 421 421 LEU LEU C . n 
C 1 413 ARG 413 422 422 ARG ARG C . n 
C 1 414 HIS 414 423 ?   ?   ?   C . n 
C 1 415 GLU 415 424 ?   ?   ?   C . n 
C 1 416 ASP 416 425 ?   ?   ?   C . n 
C 1 417 ILE 417 426 ?   ?   ?   C . n 
C 1 418 HIS 418 427 ?   ?   ?   C . n 
C 1 419 GLN 419 428 ?   ?   ?   C . n 
C 1 420 GLN 420 429 ?   ?   ?   C . n 
C 1 421 GLN 421 430 ?   ?   ?   C . n 
C 1 422 ASP 422 431 ?   ?   ?   C . n 
D 1 1   ALA 1   1   ?   ?   ?   D . n 
D 1 2   ARG 2   2   ?   ?   ?   D . n 
D 1 3   SER 3   3   ?   ?   ?   D . n 
D 1 4   ARG 4   4   ?   ?   ?   D . n 
D 1 5   SER 5   5   ?   ?   ?   D . n 
D 1 6   ALA 6   6   ?   ?   ?   D . n 
D 1 7   PRO 7   7   ?   ?   ?   D . n 
D 1 8   MET 8   8   8   MET MET D . n 
D 1 9   SER 9   9   9   SER SER D . n 
D 1 10  PRO 10  10  10  PRO PRO D . n 
D 1 11  SER 11  11  11  SER SER D . n 
D 1 12  ASP 12  12  12  ASP ASP D . n 
D 1 13  PHE 13  13  13  PHE PHE D . n 
D 1 14  LEU 14  14  14  LEU LEU D . n 
D 1 15  ASP 15  15  15  ASP ASP D . n 
D 1 16  LYS 16  16  16  LYS LYS D . n 
D 1 17  LEU 17  17  17  LEU LEU D . n 
D 1 18  MET 18  18  18  MET MET D . n 
D 1 19  GLY 19  19  19  GLY GLY D . n 
D 1 20  ARG 20  20  20  ARG ARG D . n 
D 1 21  THR 21  21  21  THR THR D . n 
D 1 22  SER 22  22  22  SER SER D . n 
D 1 23  GLY 23  23  23  GLY GLY D . n 
D 1 24  TYR 24  24  24  TYR TYR D . n 
D 1 25  ASP 25  25  25  ASP ASP D . n 
D 1 26  ALA 26  26  26  ALA ALA D . n 
D 1 27  ARG 27  27  27  ARG ARG D . n 
D 1 28  ILE 28  28  28  ILE ILE D . n 
D 1 29  ARG 29  29  29  ARG ARG D . n 
D 1 30  PRO 30  30  30  PRO PRO D . n 
D 1 31  ASN 31  31  31  ASN ASN D . n 
D 1 32  PHE 32  32  32  PHE PHE D . n 
D 1 33  LYS 33  33  33  LYS LYS D . n 
D 1 34  GLY 34  34  34  GLY GLY D . n 
D 1 35  PRO 35  35  35  PRO PRO D . n 
D 1 36  PRO 36  36  36  PRO PRO D . n 
D 1 37  VAL 37  37  37  VAL VAL D . n 
D 1 38  ASN 38  38  38  ASN ASN D . n 
D 1 39  VAL 39  39  39  VAL VAL D . n 
D 1 40  THR 40  40  40  THR THR D . n 
D 1 41  CYS 41  41  41  CYS CYS D . n 
D 1 42  ASN 42  42  42  ASN ASN D . n 
D 1 43  ILE 43  43  43  ILE ILE D . n 
D 1 44  PHE 44  44  44  PHE PHE D . n 
D 1 45  ILE 45  45  45  ILE ILE D . n 
D 1 46  ASN 46  46  46  ASN ASN D . n 
D 1 47  SER 47  47  47  SER SER D . n 
D 1 48  PHE 48  48  48  PHE PHE D . n 
D 1 49  GLY 49  49  49  GLY GLY D . n 
D 1 50  SER 50  50  50  SER SER D . n 
D 1 51  ILE 51  51  51  ILE ILE D . n 
D 1 52  ALA 52  52  52  ALA ALA D . n 
D 1 53  GLU 53  53  53  GLU GLU D . n 
D 1 54  THR 54  54  54  THR THR D . n 
D 1 55  THR 55  55  55  THR THR D . n 
D 1 56  MET 56  56  56  MET MET D . n 
D 1 57  ASP 57  57  57  ASP ASP D . n 
D 1 58  TYR 58  58  58  TYR TYR D . n 
D 1 59  ARG 59  59  59  ARG ARG D . n 
D 1 60  VAL 60  60  60  VAL VAL D . n 
D 1 61  ASN 61  61  61  ASN ASN D . n 
D 1 62  ILE 62  62  62  ILE ILE D . n 
D 1 63  PHE 63  63  63  PHE PHE D . n 
D 1 64  LEU 64  64  64  LEU LEU D . n 
D 1 65  ARG 65  65  65  ARG ARG D . n 
D 1 66  GLN 66  66  66  GLN GLN D . n 
D 1 67  LYS 67  67  67  LYS LYS D . n 
D 1 68  TRP 68  68  68  TRP TRP D . n 
D 1 69  ASN 69  69  69  ASN ASN D . n 
D 1 70  ASP 70  70  70  ASP ASP D . n 
D 1 71  PRO 71  71  71  PRO PRO D . n 
D 1 72  ARG 72  72  72  ARG ARG D . n 
D 1 73  LEU 73  73  73  LEU LEU D . n 
D 1 74  ALA 74  74  74  ALA ALA D . n 
D 1 75  TYR 75  75  75  TYR TYR D . n 
D 1 76  SER 76  76  76  SER SER D . n 
D 1 77  GLU 77  77  77  GLU GLU D . n 
D 1 78  TYR 78  78  78  TYR TYR D . n 
D 1 79  PRO 79  79  79  PRO PRO D . n 
D 1 80  ASP 80  80  80  ASP ASP D . n 
D 1 81  ASP 81  81  81  ASP ASP D . n 
D 1 82  SER 82  82  82  SER SER D . n 
D 1 83  LEU 83  83  83  LEU LEU D . n 
D 1 84  ASP 84  84  84  ASP ASP D . n 
D 1 85  LEU 85  85  85  LEU LEU D . n 
D 1 86  ASP 86  86  86  ASP ASP D . n 
D 1 87  PRO 87  87  87  PRO PRO D . n 
D 1 88  SER 88  88  88  SER SER D . n 
D 1 89  MET 89  89  89  MET MET D . n 
D 1 90  LEU 90  90  90  LEU LEU D . n 
D 1 91  ASP 91  91  91  ASP ASP D . n 
D 1 92  SER 92  92  92  SER SER D . n 
D 1 93  ILE 93  93  93  ILE ILE D . n 
D 1 94  TRP 94  94  94  TRP TRP D . n 
D 1 95  LYS 95  95  95  LYS LYS D . n 
D 1 96  PRO 96  96  96  PRO PRO D . n 
D 1 97  ASP 97  97  97  ASP ASP D . n 
D 1 98  LEU 98  98  98  LEU LEU D . n 
D 1 99  PHE 99  99  99  PHE PHE D . n 
D 1 100 PHE 100 100 100 PHE PHE D . n 
D 1 101 ALA 101 101 101 ALA ALA D . n 
D 1 102 ASN 102 102 102 ASN ASN D . n 
D 1 103 GLU 103 103 103 GLU GLU D . n 
D 1 104 LYS 104 104 104 LYS LYS D . n 
D 1 105 GLY 105 105 105 GLY GLY D . n 
D 1 106 ALA 106 106 106 ALA ALA D . n 
D 1 107 ASN 107 107 107 ASN ASN D . n 
D 1 108 PHE 108 108 108 PHE PHE D . n 
D 1 109 HIS 109 109 109 HIS HIS D . n 
D 1 110 GLU 110 110 110 GLU GLU D . n 
D 1 111 VAL 111 111 111 VAL VAL D . n 
D 1 112 THR 112 112 112 THR THR D . n 
D 1 113 THR 113 113 113 THR THR D . n 
D 1 114 ASP 114 114 114 ASP ASP D . n 
D 1 115 ASN 115 115 115 ASN ASN D . n 
D 1 116 LYS 116 116 116 LYS LYS D . n 
D 1 117 LEU 117 117 117 LEU LEU D . n 
D 1 118 LEU 118 118 118 LEU LEU D . n 
D 1 119 ARG 119 119 119 ARG ARG D . n 
D 1 120 ILE 120 120 120 ILE ILE D . n 
D 1 121 PHE 121 121 121 PHE PHE D . n 
D 1 122 LYS 122 122 122 LYS LYS D . n 
D 1 123 ASN 123 123 123 ASN ASN D . n 
D 1 124 GLY 124 124 124 GLY GLY D . n 
D 1 125 ASN 125 125 125 ASN ASN D . n 
D 1 126 VAL 126 126 126 VAL VAL D . n 
D 1 127 LEU 127 127 127 LEU LEU D . n 
D 1 128 TYR 128 128 128 TYR TYR D . n 
D 1 129 SER 129 129 129 SER SER D . n 
D 1 130 ILE 130 130 130 ILE ILE D . n 
D 1 131 ARG 131 131 131 ARG ARG D . n 
D 1 132 LEU 132 132 132 LEU LEU D . n 
D 1 133 THR 133 133 133 THR THR D . n 
D 1 134 LEU 134 134 134 LEU LEU D . n 
D 1 135 THR 135 135 135 THR THR D . n 
D 1 136 LEU 136 136 136 LEU LEU D . n 
D 1 137 SER 137 137 137 SER SER D . n 
D 1 138 CYS 138 138 138 CYS CYS D . n 
D 1 139 PRO 139 139 139 PRO PRO D . n 
D 1 140 MET 140 140 140 MET MET D . n 
D 1 141 ASP 141 141 141 ASP ASP D . n 
D 1 142 LEU 142 142 142 LEU LEU D . n 
D 1 143 LYS 143 143 143 LYS LYS D . n 
D 1 144 ASN 144 144 144 ASN ASN D . n 
D 1 145 PHE 145 145 145 PHE PHE D . n 
D 1 146 PRO 146 146 146 PRO PRO D . n 
D 1 147 MET 147 147 147 MET MET D . n 
D 1 148 ASP 148 148 148 ASP ASP D . n 
D 1 149 VAL 149 149 149 VAL VAL D . n 
D 1 150 GLN 150 150 150 GLN GLN D . n 
D 1 151 THR 151 151 151 THR THR D . n 
D 1 152 CYS 152 152 152 CYS CYS D . n 
D 1 153 ILE 153 153 153 ILE ILE D . n 
D 1 154 MET 154 154 154 MET MET D . n 
D 1 155 GLN 155 155 155 GLN GLN D . n 
D 1 156 LEU 156 156 156 LEU LEU D . n 
D 1 157 GLU 157 157 157 GLU GLU D . n 
D 1 158 SER 158 158 158 SER SER D . n 
D 1 159 PHE 159 159 159 PHE PHE D . n 
D 1 160 GLY 160 160 160 GLY GLY D . n 
D 1 161 TYR 161 161 161 TYR TYR D . n 
D 1 162 THR 162 162 162 THR THR D . n 
D 1 163 MET 163 163 163 MET MET D . n 
D 1 164 ASN 164 164 164 ASN ASN D . n 
D 1 165 ASP 165 165 165 ASP ASP D . n 
D 1 166 LEU 166 166 166 LEU LEU D . n 
D 1 167 ILE 167 167 167 ILE ILE D . n 
D 1 168 PHE 168 168 168 PHE PHE D . n 
D 1 169 GLU 169 169 169 GLU GLU D . n 
D 1 170 TRP 170 170 170 TRP TRP D . n 
D 1 171 GLN 171 171 171 GLN GLN D . n 
D 1 172 ASP 172 172 172 ASP ASP D . n 
D 1 173 GLU 173 173 173 GLU GLU D . n 
D 1 174 ALA 174 174 174 ALA ALA D . n 
D 1 175 PRO 175 175 175 PRO PRO D . n 
D 1 176 VAL 176 176 176 VAL VAL D . n 
D 1 177 GLN 177 177 177 GLN GLN D . n 
D 1 178 VAL 178 178 178 VAL VAL D . n 
D 1 179 ALA 179 179 179 ALA ALA D . n 
D 1 180 GLU 180 180 180 GLU GLU D . n 
D 1 181 GLY 181 181 181 GLY GLY D . n 
D 1 182 LEU 182 182 182 LEU LEU D . n 
D 1 183 THR 183 183 183 THR THR D . n 
D 1 184 LEU 184 184 184 LEU LEU D . n 
D 1 185 PRO 185 185 185 PRO PRO D . n 
D 1 186 GLN 186 186 186 GLN GLN D . n 
D 1 187 PHE 187 187 187 PHE PHE D . n 
D 1 188 LEU 188 188 188 LEU LEU D . n 
D 1 189 LEU 189 189 189 LEU LEU D . n 
D 1 190 LYS 190 190 190 LYS LYS D . n 
D 1 191 GLU 191 191 191 GLU GLU D . n 
D 1 192 GLU 192 192 192 GLU GLU D . n 
D 1 193 LYS 193 193 193 LYS LYS D . n 
D 1 194 ASP 194 194 194 ASP ASP D . n 
D 1 195 LEU 195 195 195 LEU LEU D . n 
D 1 196 ARG 196 196 196 ARG ARG D . n 
D 1 197 TYR 197 197 197 TYR TYR D . n 
D 1 198 CYS 198 198 198 CYS CYS D . n 
D 1 199 THR 199 199 199 THR THR D . n 
D 1 200 LYS 200 200 200 LYS LYS D . n 
D 1 201 HIS 201 201 201 HIS HIS D . n 
D 1 202 TYR 202 202 202 TYR TYR D . n 
D 1 203 ASN 203 203 203 ASN ASN D . n 
D 1 204 THR 204 204 204 THR THR D . n 
D 1 205 GLY 205 205 205 GLY GLY D . n 
D 1 206 LYS 206 206 206 LYS LYS D . n 
D 1 207 PHE 207 207 207 PHE PHE D . n 
D 1 208 THR 208 208 208 THR THR D . n 
D 1 209 CYS 209 209 209 CYS CYS D . n 
D 1 210 ILE 210 210 210 ILE ILE D . n 
D 1 211 GLU 211 211 211 GLU GLU D . n 
D 1 212 VAL 212 212 212 VAL VAL D . n 
D 1 213 ARG 213 213 213 ARG ARG D . n 
D 1 214 PHE 214 214 214 PHE PHE D . n 
D 1 215 HIS 215 215 215 HIS HIS D . n 
D 1 216 LEU 216 216 216 LEU LEU D . n 
D 1 217 GLU 217 217 217 GLU GLU D . n 
D 1 218 ARG 218 218 218 ARG ARG D . n 
D 1 219 GLN 219 219 219 GLN GLN D . n 
D 1 220 MET 220 220 220 MET MET D . n 
D 1 221 GLY 221 221 221 GLY GLY D . n 
D 1 222 TYR 222 222 222 TYR TYR D . n 
D 1 223 TYR 223 223 223 TYR TYR D . n 
D 1 224 LEU 224 224 224 LEU LEU D . n 
D 1 225 ILE 225 225 225 ILE ILE D . n 
D 1 226 GLN 226 226 226 GLN GLN D . n 
D 1 227 MET 227 227 227 MET MET D . n 
D 1 228 TYR 228 228 228 TYR TYR D . n 
D 1 229 ILE 229 229 229 ILE ILE D . n 
D 1 230 PRO 230 230 230 PRO PRO D . n 
D 1 231 SER 231 231 231 SER SER D . n 
D 1 232 LEU 232 232 232 LEU LEU D . n 
D 1 233 LEU 233 233 233 LEU LEU D . n 
D 1 234 ILE 234 234 234 ILE ILE D . n 
D 1 235 VAL 235 235 235 VAL VAL D . n 
D 1 236 ILE 236 236 236 ILE ILE D . n 
D 1 237 LEU 237 237 237 LEU LEU D . n 
D 1 238 SER 238 238 238 SER SER D . n 
D 1 239 TRP 239 239 239 TRP TRP D . n 
D 1 240 VAL 240 240 240 VAL VAL D . n 
D 1 241 SER 241 241 241 SER SER D . n 
D 1 242 PHE 242 242 242 PHE PHE D . n 
D 1 243 TRP 243 243 243 TRP TRP D . n 
D 1 244 ILE 244 244 244 ILE ILE D . n 
D 1 245 ASN 245 245 245 ASN ASN D . n 
D 1 246 MET 246 246 246 MET MET D . n 
D 1 247 ASP 247 247 247 ASP ASP D . n 
D 1 248 ALA 248 248 248 ALA ALA D . n 
D 1 249 ALA 249 249 249 ALA ALA D . n 
D 1 250 PRO 250 250 250 PRO PRO D . n 
D 1 251 ALA 251 251 251 ALA ALA D . n 
D 1 252 ARG 252 252 252 ARG ARG D . n 
D 1 253 VAL 253 253 253 VAL VAL D . n 
D 1 254 ALA 254 254 254 ALA ALA D . n 
D 1 255 LEU 255 255 255 LEU LEU D . n 
D 1 256 GLY 256 256 256 GLY GLY D . n 
D 1 257 ILE 257 257 257 ILE ILE D . n 
D 1 258 THR 258 258 258 THR THR D . n 
D 1 259 THR 259 259 259 THR THR D . n 
D 1 260 VAL 260 260 260 VAL VAL D . n 
D 1 261 LEU 261 261 261 LEU LEU D . n 
D 1 262 THR 262 262 262 THR THR D . n 
D 1 263 MET 263 263 263 MET MET D . n 
D 1 264 THR 264 264 264 THR THR D . n 
D 1 265 THR 265 265 265 THR THR D . n 
D 1 266 GLN 266 266 266 GLN GLN D . n 
D 1 267 SER 267 267 267 SER SER D . n 
D 1 268 SER 268 268 268 SER SER D . n 
D 1 269 GLY 269 269 269 GLY GLY D . n 
D 1 270 SER 270 270 270 SER SER D . n 
D 1 271 ARG 271 271 271 ARG ARG D . n 
D 1 272 ALA 272 272 272 ALA ALA D . n 
D 1 273 SER 273 273 273 SER SER D . n 
D 1 274 LEU 274 274 274 LEU LEU D . n 
D 1 275 PRO 275 275 275 PRO PRO D . n 
D 1 276 LYS 276 276 276 LYS LYS D . n 
D 1 277 VAL 277 277 277 VAL VAL D . n 
D 1 278 SER 278 278 278 SER SER D . n 
D 1 279 TYR 279 279 279 TYR TYR D . n 
D 1 280 VAL 280 280 280 VAL VAL D . n 
D 1 281 LYS 281 281 281 LYS LYS D . n 
D 1 282 ALA 282 282 282 ALA ALA D . n 
D 1 283 ILE 283 283 283 ILE ILE D . n 
D 1 284 ASP 284 284 284 ASP ASP D . n 
D 1 285 ILE 285 285 285 ILE ILE D . n 
D 1 286 TRP 286 286 286 TRP TRP D . n 
D 1 287 MET 287 287 287 MET MET D . n 
D 1 288 ALA 288 288 288 ALA ALA D . n 
D 1 289 VAL 289 289 289 VAL VAL D . n 
D 1 290 CYS 290 290 290 CYS CYS D . n 
D 1 291 LEU 291 291 291 LEU LEU D . n 
D 1 292 LEU 292 292 292 LEU LEU D . n 
D 1 293 PHE 293 293 293 PHE PHE D . n 
D 1 294 VAL 294 294 294 VAL VAL D . n 
D 1 295 PHE 295 295 295 PHE PHE D . n 
D 1 296 SER 296 296 296 SER SER D . n 
D 1 297 ALA 297 297 297 ALA ALA D . n 
D 1 298 LEU 298 298 298 LEU LEU D . n 
D 1 299 LEU 299 299 299 LEU LEU D . n 
D 1 300 GLU 300 300 300 GLU GLU D . n 
D 1 301 TYR 301 301 301 TYR TYR D . n 
D 1 302 ALA 302 302 302 ALA ALA D . n 
D 1 303 ALA 303 303 303 ALA ALA D . n 
D 1 304 VAL 304 304 304 VAL VAL D . n 
D 1 305 ASN 305 305 305 ASN ASN D . n 
D 1 306 PHE 306 306 306 PHE PHE D . n 
D 1 307 VAL 307 307 307 VAL VAL D . n 
D 1 308 SER 308 308 308 SER SER D . n 
D 1 309 ARG 309 309 309 ARG ARG D . n 
D 1 310 GLN 310 310 310 GLN GLN D . n 
D 1 311 HIS 311 320 ?   ?   ?   D . n 
D 1 312 LYS 312 321 ?   ?   ?   D . n 
D 1 313 GLU 313 322 ?   ?   ?   D . n 
D 1 314 LEU 314 323 ?   ?   ?   D . n 
D 1 315 LEU 315 324 ?   ?   ?   D . n 
D 1 316 ARG 316 325 ?   ?   ?   D . n 
D 1 317 PHE 317 326 ?   ?   ?   D . n 
D 1 318 ARG 318 327 ?   ?   ?   D . n 
D 1 319 ARG 319 328 ?   ?   ?   D . n 
D 1 320 LYS 320 329 ?   ?   ?   D . n 
D 1 321 ARG 321 330 ?   ?   ?   D . n 
D 1 322 LYS 322 331 ?   ?   ?   D . n 
D 1 323 ASN 323 332 ?   ?   ?   D . n 
D 1 324 LYS 324 333 ?   ?   ?   D . n 
D 1 325 THR 325 334 ?   ?   ?   D . n 
D 1 326 GLU 326 335 ?   ?   ?   D . n 
D 1 327 ALA 327 336 ?   ?   ?   D . n 
D 1 328 PHE 328 337 ?   ?   ?   D . n 
D 1 329 ASP 329 338 ?   ?   ?   D . n 
D 1 330 MET 330 339 ?   ?   ?   D . n 
D 1 331 ASP 331 340 ?   ?   ?   D . n 
D 1 332 ASP 332 341 ?   ?   ?   D . n 
D 1 333 GLU 333 342 ?   ?   ?   D . n 
D 1 334 VAL 334 343 ?   ?   ?   D . n 
D 1 335 ARG 335 344 ?   ?   ?   D . n 
D 1 336 GLU 336 345 ?   ?   ?   D . n 
D 1 337 GLU 337 346 ?   ?   ?   D . n 
D 1 338 ARG 338 347 ?   ?   ?   D . n 
D 1 339 PHE 339 348 ?   ?   ?   D . n 
D 1 340 SER 340 349 ?   ?   ?   D . n 
D 1 341 PHE 341 350 ?   ?   ?   D . n 
D 1 342 THR 342 351 ?   ?   ?   D . n 
D 1 343 ALA 343 352 ?   ?   ?   D . n 
D 1 344 TYR 344 353 ?   ?   ?   D . n 
D 1 345 GLY 345 354 ?   ?   ?   D . n 
D 1 346 MET 346 355 ?   ?   ?   D . n 
D 1 347 GLY 347 356 ?   ?   ?   D . n 
D 1 348 PRO 348 357 ?   ?   ?   D . n 
D 1 349 CYS 349 358 ?   ?   ?   D . n 
D 1 350 LEU 350 359 ?   ?   ?   D . n 
D 1 351 GLN 351 360 ?   ?   ?   D . n 
D 1 352 ALA 352 361 ?   ?   ?   D . n 
D 1 353 LYS 353 362 ?   ?   ?   D . n 
D 1 354 ASP 354 363 ?   ?   ?   D . n 
D 1 355 GLY 355 364 ?   ?   ?   D . n 
D 1 356 MET 356 365 ?   ?   ?   D . n 
D 1 357 THR 357 366 ?   ?   ?   D . n 
D 1 358 PRO 358 367 ?   ?   ?   D . n 
D 1 359 LYS 359 368 ?   ?   ?   D . n 
D 1 360 GLY 360 369 ?   ?   ?   D . n 
D 1 361 PRO 361 370 ?   ?   ?   D . n 
D 1 362 ASN 362 371 ?   ?   ?   D . n 
D 1 363 HIS 363 372 ?   ?   ?   D . n 
D 1 364 PRO 364 373 ?   ?   ?   D . n 
D 1 365 VAL 365 374 ?   ?   ?   D . n 
D 1 366 GLN 366 375 ?   ?   ?   D . n 
D 1 367 VAL 367 376 ?   ?   ?   D . n 
D 1 368 MET 368 377 ?   ?   ?   D . n 
D 1 369 PRO 369 378 ?   ?   ?   D . n 
D 1 370 LYS 370 379 ?   ?   ?   D . n 
D 1 371 SER 371 380 ?   ?   ?   D . n 
D 1 372 PRO 372 381 ?   ?   ?   D . n 
D 1 373 ASP 373 382 ?   ?   ?   D . n 
D 1 374 GLU 374 383 ?   ?   ?   D . n 
D 1 375 MET 375 384 ?   ?   ?   D . n 
D 1 376 ARG 376 385 385 ARG ARG D . n 
D 1 377 LYS 377 386 386 LYS LYS D . n 
D 1 378 VAL 378 387 387 VAL VAL D . n 
D 1 379 PHE 379 388 388 PHE PHE D . n 
D 1 380 ILE 380 389 389 ILE ILE D . n 
D 1 381 ASP 381 390 390 ASP ASP D . n 
D 1 382 ARG 382 391 391 ARG ARG D . n 
D 1 383 ALA 383 392 392 ALA ALA D . n 
D 1 384 LYS 384 393 393 LYS LYS D . n 
D 1 385 LYS 385 394 394 LYS LYS D . n 
D 1 386 ILE 386 395 395 ILE ILE D . n 
D 1 387 ASP 387 396 396 ASP ASP D . n 
D 1 388 THR 388 397 397 THR THR D . n 
D 1 389 ILE 389 398 398 ILE ILE D . n 
D 1 390 SER 390 399 399 SER SER D . n 
D 1 391 ARG 391 400 400 ARG ARG D . n 
D 1 392 ALA 392 401 401 ALA ALA D . n 
D 1 393 CYS 393 402 402 CYS CYS D . n 
D 1 394 PHE 394 403 403 PHE PHE D . n 
D 1 395 PRO 395 404 404 PRO PRO D . n 
D 1 396 LEU 396 405 405 LEU LEU D . n 
D 1 397 ALA 397 406 406 ALA ALA D . n 
D 1 398 PHE 398 407 407 PHE PHE D . n 
D 1 399 LEU 399 408 408 LEU LEU D . n 
D 1 400 ILE 400 409 409 ILE ILE D . n 
D 1 401 PHE 401 410 410 PHE PHE D . n 
D 1 402 ASN 402 411 411 ASN ASN D . n 
D 1 403 ILE 403 412 412 ILE ILE D . n 
D 1 404 PHE 404 413 413 PHE PHE D . n 
D 1 405 TYR 405 414 414 TYR TYR D . n 
D 1 406 TRP 406 415 415 TRP TRP D . n 
D 1 407 VAL 407 416 416 VAL VAL D . n 
D 1 408 ILE 408 417 417 ILE ILE D . n 
D 1 409 TYR 409 418 418 TYR TYR D . n 
D 1 410 LYS 410 419 419 LYS LYS D . n 
D 1 411 ILE 411 420 420 ILE ILE D . n 
D 1 412 LEU 412 421 421 LEU LEU D . n 
D 1 413 ARG 413 422 422 ARG ARG D . n 
D 1 414 HIS 414 423 423 HIS HIS D . n 
D 1 415 GLU 415 424 424 GLU GLU D . n 
D 1 416 ASP 416 425 425 ASP ASP D . n 
D 1 417 ILE 417 426 ?   ?   ?   D . n 
D 1 418 HIS 418 427 ?   ?   ?   D . n 
D 1 419 GLN 419 428 ?   ?   ?   D . n 
D 1 420 GLN 420 429 ?   ?   ?   D . n 
D 1 421 GLN 421 430 ?   ?   ?   D . n 
D 1 422 ASP 422 431 ?   ?   ?   D . n 
E 2 1   LYS 1   3   ?   ?   ?   E . n 
E 2 2   SER 2   4   ?   ?   ?   E . n 
E 2 3   SER 3   5   ?   ?   ?   E . n 
E 2 4   LYS 4   6   ?   ?   ?   E . n 
E 2 5   LYS 5   7   ?   ?   ?   E . n 
E 2 6   GLY 6   8   ?   ?   ?   E . n 
E 2 7   LYS 7   9   ?   ?   ?   E . n 
E 2 8   GLY 8   10  ?   ?   ?   E . n 
E 2 9   LYS 9   11  ?   ?   ?   E . n 
E 2 10  LYS 10  12  ?   ?   ?   E . n 
E 2 11  LYS 11  13  ?   ?   ?   E . n 
E 2 12  GLN 12  14  ?   ?   ?   E . n 
E 2 13  TYR 13  15  ?   ?   ?   E . n 
E 2 14  LEU 14  16  ?   ?   ?   E . n 
E 2 15  CYS 15  17  ?   ?   ?   E . n 
E 2 16  PRO 16  18  ?   ?   ?   E . n 
E 2 17  SER 17  19  ?   ?   ?   E . n 
E 2 18  GLN 18  20  ?   ?   ?   E . n 
E 2 19  GLN 19  21  ?   ?   ?   E . n 
E 2 20  SER 20  22  ?   ?   ?   E . n 
E 2 21  ALA 21  23  ?   ?   ?   E . n 
E 2 22  GLU 22  24  ?   ?   ?   E . n 
E 2 23  ASP 23  25  ?   ?   ?   E . n 
E 2 24  LEU 24  26  ?   ?   ?   E . n 
E 2 25  ALA 25  27  ?   ?   ?   E . n 
E 2 26  ARG 26  28  ?   ?   ?   E . n 
E 2 27  VAL 27  29  29  VAL VAL E . n 
E 2 28  PRO 28  30  30  PRO PRO E . n 
E 2 29  ALA 29  31  31  ALA ALA E . n 
E 2 30  ASN 30  32  32  ASN ASN E . n 
E 2 31  SER 31  33  33  SER SER E . n 
E 2 32  THR 32  34  34  THR THR E . n 
E 2 33  SER 33  35  35  SER SER E . n 
E 2 34  ASN 34  36  36  ASN ASN E . n 
E 2 35  ILE 35  37  37  ILE ILE E . n 
E 2 36  LEU 36  38  38  LEU LEU E . n 
E 2 37  ASN 37  39  39  ASN ASN E . n 
E 2 38  ARG 38  40  40  ARG ARG E . n 
E 2 39  LEU 39  41  41  LEU LEU E . n 
E 2 40  LEU 40  42  42  LEU LEU E . n 
E 2 41  VAL 41  43  43  VAL VAL E . n 
E 2 42  SER 42  44  44  SER SER E . n 
E 2 43  TYR 43  45  45  TYR TYR E . n 
E 2 44  ASP 44  46  46  ASP ASP E . n 
E 2 45  PRO 45  47  47  PRO PRO E . n 
E 2 46  ARG 46  48  48  ARG ARG E . n 
E 2 47  ILE 47  49  49  ILE ILE E . n 
E 2 48  ARG 48  50  50  ARG ARG E . n 
E 2 49  PRO 49  51  51  PRO PRO E . n 
E 2 50  ASN 50  52  52  ASN ASN E . n 
E 2 51  PHE 51  53  53  PHE PHE E . n 
E 2 52  LYS 52  54  54  LYS LYS E . n 
E 2 53  GLY 53  55  55  GLY GLY E . n 
E 2 54  ILE 54  56  56  ILE ILE E . n 
E 2 55  PRO 55  57  57  PRO PRO E . n 
E 2 56  VAL 56  58  58  VAL VAL E . n 
E 2 57  ASP 57  59  59  ASP ASP E . n 
E 2 58  VAL 58  60  60  VAL VAL E . n 
E 2 59  VAL 59  61  61  VAL VAL E . n 
E 2 60  VAL 60  62  62  VAL VAL E . n 
E 2 61  ASN 61  63  63  ASN ASN E . n 
E 2 62  ILE 62  64  64  ILE ILE E . n 
E 2 63  PHE 63  65  65  PHE PHE E . n 
E 2 64  ILE 64  66  66  ILE ILE E . n 
E 2 65  ASN 65  67  67  ASN ASN E . n 
E 2 66  SER 66  68  68  SER SER E . n 
E 2 67  PHE 67  69  69  PHE PHE E . n 
E 2 68  GLY 68  70  70  GLY GLY E . n 
E 2 69  SER 69  71  71  SER SER E . n 
E 2 70  ILE 70  72  72  ILE ILE E . n 
E 2 71  GLN 71  73  73  GLN GLN E . n 
E 2 72  GLU 72  74  74  GLU GLU E . n 
E 2 73  THR 73  75  75  THR THR E . n 
E 2 74  THR 74  76  76  THR THR E . n 
E 2 75  MET 75  77  77  MET MET E . n 
E 2 76  ASP 76  78  78  ASP ASP E . n 
E 2 77  TYR 77  79  79  TYR TYR E . n 
E 2 78  ARG 78  80  80  ARG ARG E . n 
E 2 79  VAL 79  81  81  VAL VAL E . n 
E 2 80  ASN 80  82  82  ASN ASN E . n 
E 2 81  ILE 81  83  83  ILE ILE E . n 
E 2 82  PHE 82  84  84  PHE PHE E . n 
E 2 83  LEU 83  85  85  LEU LEU E . n 
E 2 84  ARG 84  86  86  ARG ARG E . n 
E 2 85  GLN 85  87  87  GLN GLN E . n 
E 2 86  LYS 86  88  88  LYS LYS E . n 
E 2 87  TRP 87  89  89  TRP TRP E . n 
E 2 88  ASN 88  90  90  ASN ASN E . n 
E 2 89  ASP 89  91  91  ASP ASP E . n 
E 2 90  PRO 90  92  92  PRO PRO E . n 
E 2 91  ARG 91  93  93  ARG ARG E . n 
E 2 92  LEU 92  94  94  LEU LEU E . n 
E 2 93  LYS 93  95  95  LYS LYS E . n 
E 2 94  LEU 94  96  96  LEU LEU E . n 
E 2 95  PRO 95  97  97  PRO PRO E . n 
E 2 96  SER 96  98  98  SER SER E . n 
E 2 97  ASP 97  99  99  ASP ASP E . n 
E 2 98  PHE 98  100 100 PHE PHE E . n 
E 2 99  ARG 99  101 101 ARG ARG E . n 
E 2 100 GLY 100 102 102 GLY GLY E . n 
E 2 101 SER 101 103 103 SER SER E . n 
E 2 102 ASP 102 104 104 ASP ASP E . n 
E 2 103 ALA 103 105 105 ALA ALA E . n 
E 2 104 LEU 104 106 106 LEU LEU E . n 
E 2 105 THR 105 107 107 THR THR E . n 
E 2 106 VAL 106 108 108 VAL VAL E . n 
E 2 107 ASP 107 109 109 ASP ASP E . n 
E 2 108 PRO 108 110 110 PRO PRO E . n 
E 2 109 THR 109 111 111 THR THR E . n 
E 2 110 MET 110 112 112 MET MET E . n 
E 2 111 TYR 111 113 113 TYR TYR E . n 
E 2 112 LYS 112 114 114 LYS LYS E . n 
E 2 113 CYS 113 115 115 CYS CYS E . n 
E 2 114 LEU 114 116 116 LEU LEU E . n 
E 2 115 TRP 115 117 117 TRP TRP E . n 
E 2 116 LYS 116 118 118 LYS LYS E . n 
E 2 117 PRO 117 119 119 PRO PRO E . n 
E 2 118 ASP 118 120 120 ASP ASP E . n 
E 2 119 LEU 119 121 121 LEU LEU E . n 
E 2 120 PHE 120 122 122 PHE PHE E . n 
E 2 121 PHE 121 123 123 PHE PHE E . n 
E 2 122 ALA 122 124 124 ALA ALA E . n 
E 2 123 ASN 123 125 125 ASN ASN E . n 
E 2 124 GLU 124 126 126 GLU GLU E . n 
E 2 125 LYS 125 127 127 LYS LYS E . n 
E 2 126 SER 126 128 128 SER SER E . n 
E 2 127 ALA 127 129 129 ALA ALA E . n 
E 2 128 ASN 128 130 130 ASN ASN E . n 
E 2 129 PHE 129 131 131 PHE PHE E . n 
E 2 130 HIS 130 132 132 HIS HIS E . n 
E 2 131 ASP 131 133 133 ASP ASP E . n 
E 2 132 VAL 132 134 134 VAL VAL E . n 
E 2 133 THR 133 135 135 THR THR E . n 
E 2 134 GLN 134 136 136 GLN GLN E . n 
E 2 135 GLU 135 137 137 GLU GLU E . n 
E 2 136 ASN 136 138 138 ASN ASN E . n 
E 2 137 ILE 137 139 139 ILE ILE E . n 
E 2 138 LEU 138 140 140 LEU LEU E . n 
E 2 139 LEU 139 141 141 LEU LEU E . n 
E 2 140 PHE 140 142 142 PHE PHE E . n 
E 2 141 ILE 141 143 143 ILE ILE E . n 
E 2 142 PHE 142 144 144 PHE PHE E . n 
E 2 143 ARG 143 145 145 ARG ARG E . n 
E 2 144 ASP 144 146 146 ASP ASP E . n 
E 2 145 GLY 145 147 147 GLY GLY E . n 
E 2 146 ASP 146 148 148 ASP ASP E . n 
E 2 147 VAL 147 149 149 VAL VAL E . n 
E 2 148 LEU 148 150 150 LEU LEU E . n 
E 2 149 VAL 149 151 151 VAL VAL E . n 
E 2 150 SER 150 152 152 SER SER E . n 
E 2 151 MET 151 153 153 MET MET E . n 
E 2 152 ARG 152 154 154 ARG ARG E . n 
E 2 153 LEU 153 155 155 LEU LEU E . n 
E 2 154 SER 154 156 156 SER SER E . n 
E 2 155 ILE 155 157 157 ILE ILE E . n 
E 2 156 THR 156 158 158 THR THR E . n 
E 2 157 LEU 157 159 159 LEU LEU E . n 
E 2 158 SER 158 160 160 SER SER E . n 
E 2 159 CYS 159 161 161 CYS CYS E . n 
E 2 160 PRO 160 162 162 PRO PRO E . n 
E 2 161 LEU 161 163 163 LEU LEU E . n 
E 2 162 ASP 162 164 164 ASP ASP E . n 
E 2 163 LEU 163 165 165 LEU LEU E . n 
E 2 164 THR 164 166 166 THR THR E . n 
E 2 165 LEU 165 167 167 LEU LEU E . n 
E 2 166 PHE 166 168 168 PHE PHE E . n 
E 2 167 PRO 167 169 169 PRO PRO E . n 
E 2 168 MET 168 170 170 MET MET E . n 
E 2 169 ASP 169 171 171 ASP ASP E . n 
E 2 170 THR 170 172 172 THR THR E . n 
E 2 171 GLN 171 173 173 GLN GLN E . n 
E 2 172 ARG 172 174 174 ARG ARG E . n 
E 2 173 CYS 173 175 175 CYS CYS E . n 
E 2 174 LYS 174 176 176 LYS LYS E . n 
E 2 175 MET 175 177 177 MET MET E . n 
E 2 176 GLN 176 178 178 GLN GLN E . n 
E 2 177 LEU 177 179 179 LEU LEU E . n 
E 2 178 GLU 178 180 180 GLU GLU E . n 
E 2 179 SER 179 181 181 SER SER E . n 
E 2 180 PHE 180 182 182 PHE PHE E . n 
E 2 181 GLY 181 183 183 GLY GLY E . n 
E 2 182 TYR 182 184 184 TYR TYR E . n 
E 2 183 THR 183 185 185 THR THR E . n 
E 2 184 THR 184 186 186 THR THR E . n 
E 2 185 ASP 185 187 187 ASP ASP E . n 
E 2 186 ASP 186 188 188 ASP ASP E . n 
E 2 187 LEU 187 189 189 LEU LEU E . n 
E 2 188 ARG 188 190 190 ARG ARG E . n 
E 2 189 PHE 189 191 191 PHE PHE E . n 
E 2 190 ILE 190 192 192 ILE ILE E . n 
E 2 191 TRP 191 193 193 TRP TRP E . n 
E 2 192 GLN 192 194 194 GLN GLN E . n 
E 2 193 SER 193 195 195 SER SER E . n 
E 2 194 GLY 194 196 196 GLY GLY E . n 
E 2 195 ASP 195 197 197 ASP ASP E . n 
E 2 196 PRO 196 198 198 PRO PRO E . n 
E 2 197 VAL 197 199 199 VAL VAL E . n 
E 2 198 GLN 198 200 200 GLN GLN E . n 
E 2 199 LEU 199 201 201 LEU LEU E . n 
E 2 200 GLU 200 202 202 GLU GLU E . n 
E 2 201 LYS 201 203 203 LYS LYS E . n 
E 2 202 ILE 202 204 204 ILE ILE E . n 
E 2 203 ALA 203 205 205 ALA ALA E . n 
E 2 204 LEU 204 206 206 LEU LEU E . n 
E 2 205 PRO 205 207 207 PRO PRO E . n 
E 2 206 GLN 206 208 208 GLN GLN E . n 
E 2 207 PHE 207 209 209 PHE PHE E . n 
E 2 208 ASP 208 210 210 ASP ASP E . n 
E 2 209 ILE 209 211 211 ILE ILE E . n 
E 2 210 LYS 210 212 212 LYS LYS E . n 
E 2 211 LYS 211 213 213 LYS LYS E . n 
E 2 212 GLU 212 214 214 GLU GLU E . n 
E 2 213 ASP 213 215 215 ASP ASP E . n 
E 2 214 ILE 214 216 216 ILE ILE E . n 
E 2 215 GLU 215 217 217 GLU GLU E . n 
E 2 216 TYR 216 218 218 TYR TYR E . n 
E 2 217 GLY 217 219 219 GLY GLY E . n 
E 2 218 ASN 218 220 220 ASN ASN E . n 
E 2 219 CYS 219 221 221 CYS CYS E . n 
E 2 220 THR 220 222 222 THR THR E . n 
E 2 221 LYS 221 223 223 LYS LYS E . n 
E 2 222 TYR 222 224 224 TYR TYR E . n 
E 2 223 TYR 223 225 225 TYR TYR E . n 
E 2 224 LYS 224 226 226 LYS LYS E . n 
E 2 225 GLY 225 227 227 GLY GLY E . n 
E 2 226 THR 226 228 228 THR THR E . n 
E 2 227 GLY 227 229 229 GLY GLY E . n 
E 2 228 TYR 228 230 230 TYR TYR E . n 
E 2 229 TYR 229 231 231 TYR TYR E . n 
E 2 230 THR 230 232 232 THR THR E . n 
E 2 231 CYS 231 233 233 CYS CYS E . n 
E 2 232 VAL 232 234 234 VAL VAL E . n 
E 2 233 GLU 233 235 235 GLU GLU E . n 
E 2 234 VAL 234 236 236 VAL VAL E . n 
E 2 235 ILE 235 237 237 ILE ILE E . n 
E 2 236 PHE 236 238 238 PHE PHE E . n 
E 2 237 THR 237 239 239 THR THR E . n 
E 2 238 LEU 238 240 240 LEU LEU E . n 
E 2 239 ARG 239 241 241 ARG ARG E . n 
E 2 240 ARG 240 242 242 ARG ARG E . n 
E 2 241 GLN 241 243 243 GLN GLN E . n 
E 2 242 VAL 242 244 244 VAL VAL E . n 
E 2 243 GLY 243 245 245 GLY GLY E . n 
E 2 244 PHE 244 246 246 PHE PHE E . n 
E 2 245 TYR 245 247 247 TYR TYR E . n 
E 2 246 MET 246 248 248 MET MET E . n 
E 2 247 MET 247 249 249 MET MET E . n 
E 2 248 GLY 248 250 250 GLY GLY E . n 
E 2 249 VAL 249 251 251 VAL VAL E . n 
E 2 250 TYR 250 252 252 TYR TYR E . n 
E 2 251 ALA 251 253 253 ALA ALA E . n 
E 2 252 PRO 252 254 254 PRO PRO E . n 
E 2 253 THR 253 255 255 THR THR E . n 
E 2 254 LEU 254 256 256 LEU LEU E . n 
E 2 255 LEU 255 257 257 LEU LEU E . n 
E 2 256 ILE 256 258 258 ILE ILE E . n 
E 2 257 VAL 257 259 259 VAL VAL E . n 
E 2 258 VAL 258 260 260 VAL VAL E . n 
E 2 259 LEU 259 261 261 LEU LEU E . n 
E 2 260 SER 260 262 262 SER SER E . n 
E 2 261 TRP 261 263 263 TRP TRP E . n 
E 2 262 LEU 262 264 264 LEU LEU E . n 
E 2 263 SER 263 265 265 SER SER E . n 
E 2 264 PHE 264 266 266 PHE PHE E . n 
E 2 265 TRP 265 267 267 TRP TRP E . n 
E 2 266 ILE 266 268 268 ILE ILE E . n 
E 2 267 ASN 267 269 269 ASN ASN E . n 
E 2 268 PRO 268 270 270 PRO PRO E . n 
E 2 269 ASP 269 271 271 ASP ASP E . n 
E 2 270 ALA 270 272 272 ALA ALA E . n 
E 2 271 SER 271 273 273 SER SER E . n 
E 2 272 ALA 272 274 274 ALA ALA E . n 
E 2 273 ALA 273 275 275 ALA ALA E . n 
E 2 274 ARG 274 276 276 ARG ARG E . n 
E 2 275 VAL 275 277 277 VAL VAL E . n 
E 2 276 PRO 276 278 278 PRO PRO E . n 
E 2 277 LEU 277 279 279 LEU LEU E . n 
E 2 278 GLY 278 280 280 GLY GLY E . n 
E 2 279 ILE 279 281 281 ILE ILE E . n 
E 2 280 PHE 280 282 282 PHE PHE E . n 
E 2 281 SER 281 283 283 SER SER E . n 
E 2 282 VAL 282 284 284 VAL VAL E . n 
E 2 283 LEU 283 285 285 LEU LEU E . n 
E 2 284 SER 284 286 286 SER SER E . n 
E 2 285 LEU 285 287 287 LEU LEU E . n 
E 2 286 ALA 286 288 288 ALA ALA E . n 
E 2 287 SER 287 289 289 SER SER E . n 
E 2 288 GLU 288 290 290 GLU GLU E . n 
E 2 289 CYS 289 291 291 CYS CYS E . n 
E 2 290 THR 290 292 292 THR THR E . n 
E 2 291 THR 291 293 293 THR THR E . n 
E 2 292 LEU 292 294 294 LEU LEU E . n 
E 2 293 ALA 293 295 295 ALA ALA E . n 
E 2 294 ALA 294 296 296 ALA ALA E . n 
E 2 295 GLU 295 297 297 GLU GLU E . n 
E 2 296 LEU 296 298 298 LEU LEU E . n 
E 2 297 PRO 297 299 299 PRO PRO E . n 
E 2 298 LYS 298 300 300 LYS LYS E . n 
E 2 299 VAL 299 301 301 VAL VAL E . n 
E 2 300 SER 300 302 302 SER SER E . n 
E 2 301 TYR 301 303 303 TYR TYR E . n 
E 2 302 VAL 302 304 304 VAL VAL E . n 
E 2 303 LYS 303 305 305 LYS LYS E . n 
E 2 304 ALA 304 306 306 ALA ALA E . n 
E 2 305 LEU 305 307 307 LEU LEU E . n 
E 2 306 ASP 306 308 308 ASP ASP E . n 
E 2 307 VAL 307 309 309 VAL VAL E . n 
E 2 308 TRP 308 310 310 TRP TRP E . n 
E 2 309 LEU 309 311 311 LEU LEU E . n 
E 2 310 ILE 310 312 312 ILE ILE E . n 
E 2 311 ALA 311 313 313 ALA ALA E . n 
E 2 312 CYS 312 314 314 CYS CYS E . n 
E 2 313 LEU 313 315 315 LEU LEU E . n 
E 2 314 LEU 314 316 316 LEU LEU E . n 
E 2 315 PHE 315 317 317 PHE PHE E . n 
E 2 316 GLY 316 318 318 GLY GLY E . n 
E 2 317 PHE 317 319 319 PHE PHE E . n 
E 2 318 ALA 318 320 320 ALA ALA E . n 
E 2 319 SER 319 321 321 SER SER E . n 
E 2 320 LEU 320 322 322 LEU LEU E . n 
E 2 321 VAL 321 323 323 VAL VAL E . n 
E 2 322 GLU 322 324 324 GLU GLU E . n 
E 2 323 TYR 323 325 325 TYR TYR E . n 
E 2 324 ALA 324 326 326 ALA ALA E . n 
E 2 325 VAL 325 327 327 VAL VAL E . n 
E 2 326 VAL 326 328 328 VAL VAL E . n 
E 2 327 GLN 327 329 329 GLN GLN E . n 
E 2 328 VAL 328 330 330 VAL VAL E . n 
E 2 329 MET 329 331 331 MET MET E . n 
E 2 330 LEU 330 332 332 LEU LEU E . n 
E 2 331 ASN 331 333 333 ASN ASN E . n 
E 2 332 GLY 332 333 ?   ?   ?   E A n 
E 2 333 GLY 333 333 ?   ?   ?   E B n 
E 2 334 SER 334 333 ?   ?   ?   E C n 
E 2 335 SER 335 333 ?   ?   ?   E D n 
E 2 336 ALA 336 333 ?   ?   ?   E E n 
E 2 337 ALA 337 333 ?   ?   ?   E F n 
E 2 338 ALA 338 333 ?   ?   ?   E G n 
E 2 339 VAL 339 333 ?   ?   ?   E H n 
E 2 340 SER 340 333 ?   ?   ?   E I n 
E 2 341 LYS 341 333 ?   ?   ?   E J n 
E 2 342 GLY 342 333 ?   ?   ?   E K n 
E 2 343 GLU 343 333 ?   ?   ?   E L n 
E 2 344 GLU 344 333 ?   ?   ?   E M n 
E 2 345 LEU 345 333 ?   ?   ?   E N n 
E 2 346 PHE 346 333 ?   ?   ?   E O n 
E 2 347 THR 347 333 ?   ?   ?   E P n 
E 2 348 GLY 348 333 ?   ?   ?   E Q n 
E 2 349 VAL 349 333 ?   ?   ?   E R n 
E 2 350 VAL 350 333 ?   ?   ?   E S n 
E 2 351 PRO 351 333 ?   ?   ?   E T n 
E 2 352 ILE 352 333 ?   ?   ?   E U n 
E 2 353 LEU 353 333 ?   ?   ?   E V n 
E 2 354 VAL 354 333 ?   ?   ?   E W n 
E 2 355 GLU 355 333 ?   ?   ?   E X n 
E 2 356 LEU 356 333 ?   ?   ?   E Y n 
E 2 357 ASP 357 333 ?   ?   ?   E Z n 
E 2 358 GLY 358 334 ?   ?   ?   E A n 
E 2 359 ASP 359 334 ?   ?   ?   E B n 
E 2 360 VAL 360 334 ?   ?   ?   E C n 
E 2 361 ASN 361 334 ?   ?   ?   E D n 
E 2 362 GLY 362 334 ?   ?   ?   E E n 
E 2 363 HIS 363 334 ?   ?   ?   E F n 
E 2 364 LYS 364 334 ?   ?   ?   E G n 
E 2 365 PHE 365 334 ?   ?   ?   E H n 
E 2 366 SER 366 334 ?   ?   ?   E I n 
E 2 367 VAL 367 334 ?   ?   ?   E J n 
E 2 368 SER 368 334 ?   ?   ?   E K n 
E 2 369 GLY 369 334 ?   ?   ?   E L n 
E 2 370 GLU 370 334 ?   ?   ?   E M n 
E 2 371 GLY 371 334 ?   ?   ?   E N n 
E 2 372 GLU 372 334 ?   ?   ?   E O n 
E 2 373 GLY 373 334 ?   ?   ?   E P n 
E 2 374 ASP 374 334 ?   ?   ?   E Q n 
E 2 375 ALA 375 334 ?   ?   ?   E R n 
E 2 376 THR 376 334 ?   ?   ?   E S n 
E 2 377 TYR 377 334 ?   ?   ?   E T n 
E 2 378 GLY 378 334 ?   ?   ?   E U n 
E 2 379 LYS 379 334 ?   ?   ?   E V n 
E 2 380 LEU 380 334 ?   ?   ?   E W n 
E 2 381 THR 381 334 ?   ?   ?   E X n 
E 2 382 LEU 382 334 ?   ?   ?   E Y n 
E 2 383 LYS 383 334 ?   ?   ?   E Z n 
E 2 384 PHE 384 335 ?   ?   ?   E A n 
E 2 385 ILE 385 335 ?   ?   ?   E B n 
E 2 386 CYS 386 335 ?   ?   ?   E C n 
E 2 387 THR 387 335 ?   ?   ?   E D n 
E 2 388 THR 388 335 ?   ?   ?   E E n 
E 2 389 GLY 389 335 ?   ?   ?   E F n 
E 2 390 LYS 390 335 ?   ?   ?   E G n 
E 2 391 LEU 391 335 ?   ?   ?   E H n 
E 2 392 PRO 392 335 ?   ?   ?   E I n 
E 2 393 VAL 393 335 ?   ?   ?   E J n 
E 2 394 PRO 394 335 ?   ?   ?   E K n 
E 2 395 TRP 395 335 ?   ?   ?   E L n 
E 2 396 PRO 396 335 ?   ?   ?   E M n 
E 2 397 THR 397 335 ?   ?   ?   E N n 
E 2 398 LEU 398 335 ?   ?   ?   E O n 
E 2 399 VAL 399 335 ?   ?   ?   E P n 
E 2 400 THR 400 335 ?   ?   ?   E Q n 
E 2 401 THR 401 335 ?   ?   ?   E R n 
E 2 402 PHE 402 335 ?   ?   ?   E S n 
E 2 403 SER 403 335 ?   ?   ?   E T n 
E 2 404 TYR 404 335 ?   ?   ?   E U n 
E 2 405 GLY 405 335 ?   ?   ?   E V n 
E 2 406 VAL 406 335 ?   ?   ?   E W n 
E 2 407 GLN 407 335 ?   ?   ?   E X n 
E 2 408 CYS 408 335 ?   ?   ?   E Y n 
E 2 409 PHE 409 335 ?   ?   ?   E Z n 
E 2 410 SER 410 336 ?   ?   ?   E A n 
E 2 411 ARG 411 336 ?   ?   ?   E B n 
E 2 412 TYR 412 336 ?   ?   ?   E C n 
E 2 413 PRO 413 336 ?   ?   ?   E D n 
E 2 414 ASP 414 336 ?   ?   ?   E E n 
E 2 415 HIS 415 336 ?   ?   ?   E F n 
E 2 416 MET 416 336 ?   ?   ?   E G n 
E 2 417 LYS 417 336 ?   ?   ?   E H n 
E 2 418 GLN 418 336 ?   ?   ?   E I n 
E 2 419 HIS 419 336 ?   ?   ?   E J n 
E 2 420 ASP 420 336 ?   ?   ?   E K n 
E 2 421 PHE 421 336 ?   ?   ?   E L n 
E 2 422 PHE 422 336 ?   ?   ?   E M n 
E 2 423 LYS 423 336 ?   ?   ?   E N n 
E 2 424 SER 424 336 ?   ?   ?   E O n 
E 2 425 ALA 425 336 ?   ?   ?   E P n 
E 2 426 MET 426 336 ?   ?   ?   E Q n 
E 2 427 PRO 427 336 ?   ?   ?   E R n 
E 2 428 GLU 428 336 ?   ?   ?   E S n 
E 2 429 GLY 429 336 ?   ?   ?   E T n 
E 2 430 TYR 430 336 ?   ?   ?   E U n 
E 2 431 VAL 431 336 ?   ?   ?   E V n 
E 2 432 GLN 432 336 ?   ?   ?   E W n 
E 2 433 GLU 433 336 ?   ?   ?   E X n 
E 2 434 ARG 434 336 ?   ?   ?   E Y n 
E 2 435 THR 435 336 ?   ?   ?   E Z n 
E 2 436 ILE 436 337 ?   ?   ?   E A n 
E 2 437 PHE 437 337 ?   ?   ?   E B n 
E 2 438 PHE 438 337 ?   ?   ?   E C n 
E 2 439 LYS 439 337 ?   ?   ?   E D n 
E 2 440 ASP 440 337 ?   ?   ?   E E n 
E 2 441 ASP 441 337 ?   ?   ?   E F n 
E 2 442 GLY 442 337 ?   ?   ?   E G n 
E 2 443 ASN 443 337 ?   ?   ?   E H n 
E 2 444 TYR 444 337 ?   ?   ?   E I n 
E 2 445 LYS 445 337 ?   ?   ?   E J n 
E 2 446 THR 446 337 ?   ?   ?   E K n 
E 2 447 ARG 447 337 ?   ?   ?   E L n 
E 2 448 ALA 448 337 ?   ?   ?   E M n 
E 2 449 GLU 449 337 ?   ?   ?   E N n 
E 2 450 VAL 450 337 ?   ?   ?   E O n 
E 2 451 LYS 451 337 ?   ?   ?   E P n 
E 2 452 PHE 452 337 ?   ?   ?   E Q n 
E 2 453 GLU 453 337 ?   ?   ?   E R n 
E 2 454 GLY 454 337 ?   ?   ?   E S n 
E 2 455 ASP 455 337 ?   ?   ?   E T n 
E 2 456 THR 456 337 ?   ?   ?   E U n 
E 2 457 LEU 457 337 ?   ?   ?   E V n 
E 2 458 VAL 458 337 ?   ?   ?   E W n 
E 2 459 ASN 459 337 ?   ?   ?   E X n 
E 2 460 ARG 460 337 ?   ?   ?   E Y n 
E 2 461 ILE 461 337 ?   ?   ?   E Z n 
E 2 462 GLU 462 338 ?   ?   ?   E A n 
E 2 463 LEU 463 338 ?   ?   ?   E B n 
E 2 464 LYS 464 338 ?   ?   ?   E C n 
E 2 465 GLY 465 338 ?   ?   ?   E D n 
E 2 466 ILE 466 338 ?   ?   ?   E E n 
E 2 467 ASP 467 338 ?   ?   ?   E F n 
E 2 468 PHE 468 338 ?   ?   ?   E G n 
E 2 469 LYS 469 338 ?   ?   ?   E H n 
E 2 470 GLU 470 338 ?   ?   ?   E I n 
E 2 471 ASP 471 338 ?   ?   ?   E J n 
E 2 472 GLY 472 338 ?   ?   ?   E K n 
E 2 473 ASN 473 338 ?   ?   ?   E L n 
E 2 474 ILE 474 338 ?   ?   ?   E M n 
E 2 475 LEU 475 338 ?   ?   ?   E N n 
E 2 476 GLY 476 338 ?   ?   ?   E O n 
E 2 477 HIS 477 338 ?   ?   ?   E P n 
E 2 478 LYS 478 338 ?   ?   ?   E Q n 
E 2 479 LEU 479 338 ?   ?   ?   E R n 
E 2 480 GLU 480 338 ?   ?   ?   E S n 
E 2 481 TYR 481 338 ?   ?   ?   E T n 
E 2 482 ASN 482 338 ?   ?   ?   E U n 
E 2 483 TYR 483 338 ?   ?   ?   E V n 
E 2 484 ASN 484 338 ?   ?   ?   E W n 
E 2 485 SER 485 338 ?   ?   ?   E X n 
E 2 486 HIS 486 338 ?   ?   ?   E Y n 
E 2 487 ASN 487 338 ?   ?   ?   E Z n 
E 2 488 VAL 488 339 ?   ?   ?   E A n 
E 2 489 TYR 489 339 ?   ?   ?   E B n 
E 2 490 ILE 490 339 ?   ?   ?   E C n 
E 2 491 MET 491 339 ?   ?   ?   E D n 
E 2 492 ALA 492 339 ?   ?   ?   E E n 
E 2 493 ASP 493 339 ?   ?   ?   E F n 
E 2 494 LYS 494 339 ?   ?   ?   E G n 
E 2 495 GLN 495 339 ?   ?   ?   E H n 
E 2 496 LYS 496 339 ?   ?   ?   E I n 
E 2 497 ASN 497 339 ?   ?   ?   E J n 
E 2 498 GLY 498 339 ?   ?   ?   E K n 
E 2 499 ILE 499 339 ?   ?   ?   E L n 
E 2 500 LYS 500 339 ?   ?   ?   E M n 
E 2 501 VAL 501 339 ?   ?   ?   E N n 
E 2 502 ASN 502 339 ?   ?   ?   E O n 
E 2 503 PHE 503 339 ?   ?   ?   E P n 
E 2 504 LYS 504 339 ?   ?   ?   E Q n 
E 2 505 ILE 505 339 ?   ?   ?   E R n 
E 2 506 ARG 506 339 ?   ?   ?   E S n 
E 2 507 HIS 507 339 ?   ?   ?   E T n 
E 2 508 ASN 508 339 ?   ?   ?   E U n 
E 2 509 ILE 509 339 ?   ?   ?   E V n 
E 2 510 GLU 510 339 ?   ?   ?   E W n 
E 2 511 ASP 511 339 ?   ?   ?   E X n 
E 2 512 GLY 512 339 ?   ?   ?   E Y n 
E 2 513 SER 513 339 ?   ?   ?   E Z n 
E 2 514 VAL 514 340 ?   ?   ?   E A n 
E 2 515 GLN 515 340 ?   ?   ?   E B n 
E 2 516 LEU 516 340 ?   ?   ?   E C n 
E 2 517 ALA 517 340 ?   ?   ?   E D n 
E 2 518 ASP 518 340 ?   ?   ?   E E n 
E 2 519 HIS 519 340 ?   ?   ?   E F n 
E 2 520 TYR 520 340 ?   ?   ?   E G n 
E 2 521 GLN 521 340 ?   ?   ?   E H n 
E 2 522 GLN 522 340 ?   ?   ?   E I n 
E 2 523 ASN 523 340 ?   ?   ?   E J n 
E 2 524 THR 524 340 ?   ?   ?   E K n 
E 2 525 PRO 525 340 ?   ?   ?   E L n 
E 2 526 ILE 526 340 ?   ?   ?   E M n 
E 2 527 GLY 527 340 ?   ?   ?   E N n 
E 2 528 ASP 528 340 ?   ?   ?   E O n 
E 2 529 GLY 529 340 ?   ?   ?   E P n 
E 2 530 PRO 530 340 ?   ?   ?   E Q n 
E 2 531 VAL 531 340 ?   ?   ?   E R n 
E 2 532 LEU 532 340 ?   ?   ?   E S n 
E 2 533 LEU 533 340 ?   ?   ?   E T n 
E 2 534 PRO 534 340 ?   ?   ?   E U n 
E 2 535 ASP 535 340 ?   ?   ?   E V n 
E 2 536 ASN 536 340 ?   ?   ?   E W n 
E 2 537 HIS 537 340 ?   ?   ?   E X n 
E 2 538 TYR 538 340 ?   ?   ?   E Y n 
E 2 539 LEU 539 340 ?   ?   ?   E Z n 
E 2 540 SER 540 341 ?   ?   ?   E A n 
E 2 541 THR 541 341 ?   ?   ?   E B n 
E 2 542 GLN 542 341 ?   ?   ?   E C n 
E 2 543 SER 543 341 ?   ?   ?   E D n 
E 2 544 ALA 544 341 ?   ?   ?   E E n 
E 2 545 LEU 545 341 ?   ?   ?   E F n 
E 2 546 SER 546 341 ?   ?   ?   E G n 
E 2 547 LYS 547 341 ?   ?   ?   E H n 
E 2 548 ASP 548 341 ?   ?   ?   E I n 
E 2 549 PRO 549 341 ?   ?   ?   E J n 
E 2 550 ASN 550 341 ?   ?   ?   E K n 
E 2 551 GLU 551 341 ?   ?   ?   E L n 
E 2 552 LYS 552 341 ?   ?   ?   E M n 
E 2 553 ARG 553 341 ?   ?   ?   E N n 
E 2 554 ASP 554 341 ?   ?   ?   E O n 
E 2 555 HIS 555 341 ?   ?   ?   E P n 
E 2 556 MET 556 341 ?   ?   ?   E Q n 
E 2 557 VAL 557 341 ?   ?   ?   E R n 
E 2 558 LEU 558 341 ?   ?   ?   E S n 
E 2 559 LEU 559 341 ?   ?   ?   E T n 
E 2 560 GLU 560 341 ?   ?   ?   E U n 
E 2 561 PHE 561 341 ?   ?   ?   E V n 
E 2 562 VAL 562 341 ?   ?   ?   E W n 
E 2 563 THR 563 341 ?   ?   ?   E X n 
E 2 564 ALA 564 341 ?   ?   ?   E Y n 
E 2 565 ALA 565 341 ?   ?   ?   E Z n 
E 2 566 GLY 566 342 ?   ?   ?   E A n 
E 2 567 ILE 567 342 ?   ?   ?   E B n 
E 2 568 THR 568 342 ?   ?   ?   E C n 
E 2 569 HIS 569 342 ?   ?   ?   E D n 
E 2 570 GLY 570 342 ?   ?   ?   E E n 
E 2 571 MET 571 342 ?   ?   ?   E F n 
E 2 572 ASP 572 342 ?   ?   ?   E G n 
E 2 573 GLU 573 342 ?   ?   ?   E H n 
E 2 574 LEU 574 342 ?   ?   ?   E I n 
E 2 575 TYR 575 342 ?   ?   ?   E J n 
E 2 576 LYS 576 342 ?   ?   ?   E K n 
E 2 577 SER 577 342 ?   ?   ?   E L n 
E 2 578 GLY 578 342 ?   ?   ?   E M n 
E 2 579 SER 579 342 ?   ?   ?   E N n 
E 2 580 GLY 580 342 ?   ?   ?   E O n 
E 2 581 SER 581 342 ?   ?   ?   E P n 
E 2 582 GLY 582 342 ?   ?   ?   E Q n 
E 2 583 VAL 583 342 ?   ?   ?   E R n 
E 2 584 GLY 584 342 ?   ?   ?   E S n 
E 2 585 GLU 585 342 ?   ?   ?   E T n 
E 2 586 THR 586 342 ?   ?   ?   E U n 
E 2 587 ARG 587 342 ?   ?   ?   E V n 
E 2 588 CYS 588 342 ?   ?   ?   E W n 
E 2 589 LYS 589 342 ?   ?   ?   E X n 
E 2 590 LYS 590 342 ?   ?   ?   E Y n 
E 2 591 VAL 591 342 ?   ?   ?   E Z n 
E 2 592 CYS 592 343 ?   ?   ?   E A n 
E 2 593 THR 593 343 ?   ?   ?   E B n 
E 2 594 SER 594 343 ?   ?   ?   E C n 
E 2 595 LYS 595 343 ?   ?   ?   E D n 
E 2 596 SER 596 343 ?   ?   ?   E E n 
E 2 597 ASP 597 343 ?   ?   ?   E F n 
E 2 598 LEU 598 343 ?   ?   ?   E G n 
E 2 599 ARG 599 343 ?   ?   ?   E H n 
E 2 600 SER 600 343 ?   ?   ?   E I n 
E 2 601 ASN 601 343 ?   ?   ?   E J n 
E 2 602 ASP 602 343 ?   ?   ?   E K n 
E 2 603 PHE 603 343 ?   ?   ?   E L n 
E 2 604 SER 604 343 ?   ?   ?   E M n 
E 2 605 ILE 605 343 ?   ?   ?   E N n 
E 2 606 VAL 606 343 ?   ?   ?   E O n 
E 2 607 GLY 607 343 ?   ?   ?   E P n 
E 2 608 SER 608 343 ?   ?   ?   E Q n 
E 2 609 LEU 609 343 ?   ?   ?   E R n 
E 2 610 PRO 610 343 ?   ?   ?   E S n 
E 2 611 ARG 611 343 ?   ?   ?   E T n 
E 2 612 ASP 612 343 ?   ?   ?   E U n 
E 2 613 PHE 613 343 ?   ?   ?   E V n 
E 2 614 GLU 614 343 ?   ?   ?   E W n 
E 2 615 LEU 615 343 ?   ?   ?   E X n 
E 2 616 SER 616 343 ?   ?   ?   E Y n 
E 2 617 ASN 617 343 ?   ?   ?   E Z n 
E 2 618 TYR 618 344 ?   ?   ?   E A n 
E 2 619 ASP 619 344 ?   ?   ?   E B n 
E 2 620 CYS 620 344 ?   ?   ?   E C n 
E 2 621 TYR 621 344 ?   ?   ?   E D n 
E 2 622 GLY 622 344 ?   ?   ?   E E n 
E 2 623 LYS 623 344 ?   ?   ?   E F n 
E 2 624 PRO 624 344 ?   ?   ?   E G n 
E 2 625 ILE 625 344 ?   ?   ?   E H n 
E 2 626 GLU 626 344 ?   ?   ?   E I n 
E 2 627 VAL 627 344 ?   ?   ?   E J n 
E 2 628 ASN 628 344 ?   ?   ?   E K n 
E 2 629 ASN 629 344 ?   ?   ?   E L n 
E 2 630 GLY 630 344 ?   ?   ?   E M n 
E 2 631 LEU 631 344 ?   ?   ?   E N n 
E 2 632 GLY 632 344 ?   ?   ?   E O n 
E 2 633 LYS 633 344 ?   ?   ?   E P n 
E 2 634 SER 634 344 ?   ?   ?   E Q n 
E 2 635 GLN 635 344 ?   ?   ?   E R n 
E 2 636 ALA 636 344 ?   ?   ?   E S n 
E 2 637 LYS 637 344 ?   ?   ?   E T n 
E 2 638 ASN 638 344 ?   ?   ?   E U n 
E 2 639 ASN 639 344 ?   ?   ?   E V n 
E 2 640 LYS 640 344 ?   ?   ?   E W n 
E 2 641 LYS 641 344 ?   ?   ?   E X n 
E 2 642 PRO 642 344 ?   ?   ?   E Y n 
E 2 643 PRO 643 344 ?   ?   ?   E Z n 
E 2 644 PRO 644 345 ?   ?   ?   E A n 
E 2 645 ALA 645 345 ?   ?   ?   E B n 
E 2 646 LYS 646 345 ?   ?   ?   E C n 
E 2 647 PRO 647 345 ?   ?   ?   E D n 
E 2 648 VAL 648 345 ?   ?   ?   E E n 
E 2 649 ILE 649 444 444 ILE ILE E . n 
E 2 650 PRO 650 445 445 PRO PRO E . n 
E 2 651 THR 651 446 446 THR THR E . n 
E 2 652 ALA 652 447 447 ALA ALA E . n 
E 2 653 ALA 653 448 448 ALA ALA E . n 
E 2 654 LYS 654 449 449 LYS LYS E . n 
E 2 655 ARG 655 450 450 ARG ARG E . n 
E 2 656 ILE 656 451 451 ILE ILE E . n 
E 2 657 ASP 657 452 452 ASP ASP E . n 
E 2 658 LEU 658 453 453 LEU LEU E . n 
E 2 659 TYR 659 454 454 TYR TYR E . n 
E 2 660 ALA 660 455 455 ALA ALA E . n 
E 2 661 ARG 661 456 456 ARG ARG E . n 
E 2 662 ALA 662 457 457 ALA ALA E . n 
E 2 663 LEU 663 458 458 LEU LEU E . n 
E 2 664 PHE 664 459 459 PHE PHE E . n 
E 2 665 PRO 665 460 460 PRO PRO E . n 
E 2 666 PHE 666 461 461 PHE PHE E . n 
E 2 667 CYS 667 462 462 CYS CYS E . n 
E 2 668 PHE 668 463 463 PHE PHE E . n 
E 2 669 LEU 669 464 464 LEU LEU E . n 
E 2 670 PHE 670 465 465 PHE PHE E . n 
E 2 671 PHE 671 466 466 PHE PHE E . n 
E 2 672 ASN 672 467 467 ASN ASN E . n 
E 2 673 VAL 673 468 468 VAL VAL E . n 
E 2 674 ILE 674 469 469 ILE ILE E . n 
E 2 675 TYR 675 470 470 TYR TYR E . n 
E 2 676 TRP 676 471 471 TRP TRP E . n 
E 2 677 SER 677 472 472 SER SER E . n 
E 2 678 ILE 678 473 473 ILE ILE E . n 
E 2 679 TYR 679 474 474 TYR TYR E . n 
E 2 680 LEU 680 475 475 LEU LEU E . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 GLY ? ? GLY ? ? 'SUBJECT OF INVESTIGATION' ? 
2 NAG ? ? NAG ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
F 3 NAG 1 501 501 NAG NAG A . 
G 4 GLY 1 502 502 GLY GLY A . 
H 3 NAG 1 501 501 NAG NAG B . 
I 4 GLY 1 502 502 GLY GLY B . 
J 3 NAG 1 501 501 NAG NAG C . 
K 3 NAG 1 501 501 NAG NAG D . 
L 4 GLY 1 502 502 GLY GLY D . 
M 3 NAG 1 501 501 NAG NAG E . 
N 4 GLY 1 502 502 GLY GLY E . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A ARG 20  ? CG  ? A ARG 20  CG  
2   1 Y 1 A ARG 20  ? CD  ? A ARG 20  CD  
3   1 Y 1 A ARG 20  ? NE  ? A ARG 20  NE  
4   1 Y 1 A ARG 20  ? CZ  ? A ARG 20  CZ  
5   1 Y 1 A ARG 20  ? NH1 ? A ARG 20  NH1 
6   1 Y 1 A ARG 20  ? NH2 ? A ARG 20  NH2 
7   1 Y 1 A GLU 77  ? CG  ? A GLU 77  CG  
8   1 Y 1 A GLU 77  ? CD  ? A GLU 77  CD  
9   1 Y 1 A GLU 77  ? OE1 ? A GLU 77  OE1 
10  1 Y 1 A GLU 77  ? OE2 ? A GLU 77  OE2 
11  1 Y 1 A LYS 143 ? CG  ? A LYS 143 CG  
12  1 Y 1 A LYS 143 ? CD  ? A LYS 143 CD  
13  1 Y 1 A LYS 143 ? CE  ? A LYS 143 CE  
14  1 Y 1 A LYS 143 ? NZ  ? A LYS 143 NZ  
15  1 Y 1 A GLU 180 ? CG  ? A GLU 180 CG  
16  1 Y 1 A GLU 180 ? CD  ? A GLU 180 CD  
17  1 Y 1 A GLU 180 ? OE1 ? A GLU 180 OE1 
18  1 Y 1 A GLU 180 ? OE2 ? A GLU 180 OE2 
19  1 Y 1 A ARG 309 ? CG  ? A ARG 309 CG  
20  1 Y 1 A ARG 309 ? CD  ? A ARG 309 CD  
21  1 Y 1 A ARG 309 ? NE  ? A ARG 309 NE  
22  1 Y 1 A ARG 309 ? CZ  ? A ARG 309 CZ  
23  1 Y 1 A ARG 309 ? NH1 ? A ARG 309 NH1 
24  1 Y 1 A ARG 309 ? NH2 ? A ARG 309 NH2 
25  1 Y 1 A PHE 388 ? CG  ? A PHE 379 CG  
26  1 Y 1 A PHE 388 ? CD1 ? A PHE 379 CD1 
27  1 Y 1 A PHE 388 ? CD2 ? A PHE 379 CD2 
28  1 Y 1 A PHE 388 ? CE1 ? A PHE 379 CE1 
29  1 Y 1 A PHE 388 ? CE2 ? A PHE 379 CE2 
30  1 Y 1 A PHE 388 ? CZ  ? A PHE 379 CZ  
31  1 Y 1 A LYS 393 ? CG  ? A LYS 384 CG  
32  1 Y 1 A LYS 393 ? CD  ? A LYS 384 CD  
33  1 Y 1 A LYS 393 ? CE  ? A LYS 384 CE  
34  1 Y 1 A LYS 393 ? NZ  ? A LYS 384 NZ  
35  1 Y 1 A THR 397 ? OG1 ? A THR 388 OG1 
36  1 Y 1 A THR 397 ? CG2 ? A THR 388 CG2 
37  1 Y 1 A ILE 398 ? CG1 ? A ILE 389 CG1 
38  1 Y 1 A ILE 398 ? CG2 ? A ILE 389 CG2 
39  1 Y 1 A ILE 398 ? CD1 ? A ILE 389 CD1 
40  1 Y 1 A ARG 400 ? CG  ? A ARG 391 CG  
41  1 Y 1 A ARG 400 ? CD  ? A ARG 391 CD  
42  1 Y 1 A ARG 400 ? NE  ? A ARG 391 NE  
43  1 Y 1 A ARG 400 ? CZ  ? A ARG 391 CZ  
44  1 Y 1 A ARG 400 ? NH1 ? A ARG 391 NH1 
45  1 Y 1 A ARG 400 ? NH2 ? A ARG 391 NH2 
46  1 Y 1 B ARG 20  ? CG  ? B ARG 20  CG  
47  1 Y 1 B ARG 20  ? CD  ? B ARG 20  CD  
48  1 Y 1 B ARG 20  ? NE  ? B ARG 20  NE  
49  1 Y 1 B ARG 20  ? CZ  ? B ARG 20  CZ  
50  1 Y 1 B ARG 20  ? NH1 ? B ARG 20  NH1 
51  1 Y 1 B ARG 20  ? NH2 ? B ARG 20  NH2 
52  1 Y 1 B LYS 143 ? CG  ? B LYS 143 CG  
53  1 Y 1 B LYS 143 ? CD  ? B LYS 143 CD  
54  1 Y 1 B LYS 143 ? CE  ? B LYS 143 CE  
55  1 Y 1 B LYS 143 ? NZ  ? B LYS 143 NZ  
56  1 Y 1 B GLU 180 ? CG  ? B GLU 180 CG  
57  1 Y 1 B GLU 180 ? CD  ? B GLU 180 CD  
58  1 Y 1 B GLU 180 ? OE1 ? B GLU 180 OE1 
59  1 Y 1 B GLU 180 ? OE2 ? B GLU 180 OE2 
60  1 Y 1 B ARG 309 ? CG  ? B ARG 309 CG  
61  1 Y 1 B ARG 309 ? CD  ? B ARG 309 CD  
62  1 Y 1 B ARG 309 ? NE  ? B ARG 309 NE  
63  1 Y 1 B ARG 309 ? CZ  ? B ARG 309 CZ  
64  1 Y 1 B ARG 309 ? NH1 ? B ARG 309 NH1 
65  1 Y 1 B ARG 309 ? NH2 ? B ARG 309 NH2 
66  1 Y 1 B ASP 396 ? CG  ? B ASP 387 CG  
67  1 Y 1 B ASP 396 ? OD1 ? B ASP 387 OD1 
68  1 Y 1 B ASP 396 ? OD2 ? B ASP 387 OD2 
69  1 Y 1 B THR 397 ? OG1 ? B THR 388 OG1 
70  1 Y 1 B THR 397 ? CG2 ? B THR 388 CG2 
71  1 Y 1 B ILE 398 ? CG1 ? B ILE 389 CG1 
72  1 Y 1 B ILE 398 ? CG2 ? B ILE 389 CG2 
73  1 Y 1 B ILE 398 ? CD1 ? B ILE 389 CD1 
74  1 Y 1 B SER 399 ? OG  ? B SER 390 OG  
75  1 Y 1 B ARG 400 ? CG  ? B ARG 391 CG  
76  1 Y 1 B ARG 400 ? CD  ? B ARG 391 CD  
77  1 Y 1 B ARG 400 ? NE  ? B ARG 391 NE  
78  1 Y 1 B ARG 400 ? CZ  ? B ARG 391 CZ  
79  1 Y 1 B ARG 400 ? NH1 ? B ARG 391 NH1 
80  1 Y 1 B ARG 400 ? NH2 ? B ARG 391 NH2 
81  1 Y 1 C ARG 20  ? CG  ? C ARG 20  CG  
82  1 Y 1 C ARG 20  ? CD  ? C ARG 20  CD  
83  1 Y 1 C ARG 20  ? NE  ? C ARG 20  NE  
84  1 Y 1 C ARG 20  ? CZ  ? C ARG 20  CZ  
85  1 Y 1 C ARG 20  ? NH1 ? C ARG 20  NH1 
86  1 Y 1 C ARG 20  ? NH2 ? C ARG 20  NH2 
87  1 Y 1 C LYS 143 ? CG  ? C LYS 143 CG  
88  1 Y 1 C LYS 143 ? CD  ? C LYS 143 CD  
89  1 Y 1 C LYS 143 ? CE  ? C LYS 143 CE  
90  1 Y 1 C LYS 143 ? NZ  ? C LYS 143 NZ  
91  1 Y 1 C GLU 180 ? CG  ? C GLU 180 CG  
92  1 Y 1 C GLU 180 ? CD  ? C GLU 180 CD  
93  1 Y 1 C GLU 180 ? OE1 ? C GLU 180 OE1 
94  1 Y 1 C GLU 180 ? OE2 ? C GLU 180 OE2 
95  1 Y 1 C ARG 309 ? CG  ? C ARG 309 CG  
96  1 Y 1 C ARG 309 ? CD  ? C ARG 309 CD  
97  1 Y 1 C ARG 309 ? NE  ? C ARG 309 NE  
98  1 Y 1 C ARG 309 ? CZ  ? C ARG 309 CZ  
99  1 Y 1 C ARG 309 ? NH1 ? C ARG 309 NH1 
100 1 Y 1 C ARG 309 ? NH2 ? C ARG 309 NH2 
101 1 Y 1 C ASP 396 ? CG  ? C ASP 387 CG  
102 1 Y 1 C ASP 396 ? OD1 ? C ASP 387 OD1 
103 1 Y 1 C ASP 396 ? OD2 ? C ASP 387 OD2 
104 1 Y 1 C ILE 398 ? CG1 ? C ILE 389 CG1 
105 1 Y 1 C ILE 398 ? CG2 ? C ILE 389 CG2 
106 1 Y 1 C ILE 398 ? CD1 ? C ILE 389 CD1 
107 1 Y 1 C SER 399 ? OG  ? C SER 390 OG  
108 1 Y 1 C ARG 400 ? CG  ? C ARG 391 CG  
109 1 Y 1 C ARG 400 ? CD  ? C ARG 391 CD  
110 1 Y 1 C ARG 400 ? NE  ? C ARG 391 NE  
111 1 Y 1 C ARG 400 ? CZ  ? C ARG 391 CZ  
112 1 Y 1 C ARG 400 ? NH1 ? C ARG 391 NH1 
113 1 Y 1 C ARG 400 ? NH2 ? C ARG 391 NH2 
114 1 Y 1 C ARG 422 ? CG  ? C ARG 413 CG  
115 1 Y 1 C ARG 422 ? CD  ? C ARG 413 CD  
116 1 Y 1 C ARG 422 ? NE  ? C ARG 413 NE  
117 1 Y 1 C ARG 422 ? CZ  ? C ARG 413 CZ  
118 1 Y 1 C ARG 422 ? NH1 ? C ARG 413 NH1 
119 1 Y 1 C ARG 422 ? NH2 ? C ARG 413 NH2 
120 1 Y 1 D ARG 20  ? CG  ? D ARG 20  CG  
121 1 Y 1 D ARG 20  ? CD  ? D ARG 20  CD  
122 1 Y 1 D ARG 20  ? NE  ? D ARG 20  NE  
123 1 Y 1 D ARG 20  ? CZ  ? D ARG 20  CZ  
124 1 Y 1 D ARG 20  ? NH1 ? D ARG 20  NH1 
125 1 Y 1 D ARG 20  ? NH2 ? D ARG 20  NH2 
126 1 Y 1 D GLU 77  ? CG  ? D GLU 77  CG  
127 1 Y 1 D GLU 77  ? CD  ? D GLU 77  CD  
128 1 Y 1 D GLU 77  ? OE1 ? D GLU 77  OE1 
129 1 Y 1 D GLU 77  ? OE2 ? D GLU 77  OE2 
130 1 Y 1 D LYS 143 ? CG  ? D LYS 143 CG  
131 1 Y 1 D LYS 143 ? CD  ? D LYS 143 CD  
132 1 Y 1 D LYS 143 ? CE  ? D LYS 143 CE  
133 1 Y 1 D LYS 143 ? NZ  ? D LYS 143 NZ  
134 1 Y 1 D GLU 180 ? CG  ? D GLU 180 CG  
135 1 Y 1 D GLU 180 ? CD  ? D GLU 180 CD  
136 1 Y 1 D GLU 180 ? OE1 ? D GLU 180 OE1 
137 1 Y 1 D GLU 180 ? OE2 ? D GLU 180 OE2 
138 1 Y 1 D ARG 309 ? CG  ? D ARG 309 CG  
139 1 Y 1 D ARG 309 ? CD  ? D ARG 309 CD  
140 1 Y 1 D ARG 309 ? NE  ? D ARG 309 NE  
141 1 Y 1 D ARG 309 ? CZ  ? D ARG 309 CZ  
142 1 Y 1 D ARG 309 ? NH1 ? D ARG 309 NH1 
143 1 Y 1 D ARG 309 ? NH2 ? D ARG 309 NH2 
144 1 Y 1 D ASP 396 ? CG  ? D ASP 387 CG  
145 1 Y 1 D ASP 396 ? OD1 ? D ASP 387 OD1 
146 1 Y 1 D ASP 396 ? OD2 ? D ASP 387 OD2 
147 1 Y 1 D ILE 398 ? CG1 ? D ILE 389 CG1 
148 1 Y 1 D ILE 398 ? CG2 ? D ILE 389 CG2 
149 1 Y 1 D ILE 398 ? CD1 ? D ILE 389 CD1 
150 1 Y 1 D SER 399 ? OG  ? D SER 390 OG  
151 1 Y 1 D ARG 400 ? CG  ? D ARG 391 CG  
152 1 Y 1 D ARG 400 ? CD  ? D ARG 391 CD  
153 1 Y 1 D ARG 400 ? NE  ? D ARG 391 NE  
154 1 Y 1 D ARG 400 ? CZ  ? D ARG 391 CZ  
155 1 Y 1 D ARG 400 ? NH1 ? D ARG 391 NH1 
156 1 Y 1 D ARG 400 ? NH2 ? D ARG 391 NH2 
157 1 Y 1 E GLU 74  ? CG  ? E GLU 72  CG  
158 1 Y 1 E GLU 74  ? CD  ? E GLU 72  CD  
159 1 Y 1 E GLU 74  ? OE1 ? E GLU 72  OE1 
160 1 Y 1 E GLU 74  ? OE2 ? E GLU 72  OE2 
161 1 Y 1 E ARG 101 ? CG  ? E ARG 99  CG  
162 1 Y 1 E ARG 101 ? CD  ? E ARG 99  CD  
163 1 Y 1 E ARG 101 ? NE  ? E ARG 99  NE  
164 1 Y 1 E ARG 101 ? CZ  ? E ARG 99  CZ  
165 1 Y 1 E ARG 101 ? NH1 ? E ARG 99  NH1 
166 1 Y 1 E ARG 101 ? NH2 ? E ARG 99  NH2 
167 1 Y 1 E LYS 203 ? CG  ? E LYS 201 CG  
168 1 Y 1 E LYS 203 ? CD  ? E LYS 201 CD  
169 1 Y 1 E LYS 203 ? CE  ? E LYS 201 CE  
170 1 Y 1 E LYS 203 ? NZ  ? E LYS 201 NZ  
171 1 Y 1 E LYS 213 ? CG  ? E LYS 211 CG  
172 1 Y 1 E LYS 213 ? CD  ? E LYS 211 CD  
173 1 Y 1 E LYS 213 ? CE  ? E LYS 211 CE  
174 1 Y 1 E LYS 213 ? NZ  ? E LYS 211 NZ  
175 1 Y 1 E LYS 226 ? CG  ? E LYS 224 CG  
176 1 Y 1 E LYS 226 ? CD  ? E LYS 224 CD  
177 1 Y 1 E LYS 226 ? CE  ? E LYS 224 CE  
178 1 Y 1 E LYS 226 ? NZ  ? E LYS 224 NZ  
179 1 Y 1 E MET 331 ? CG  ? E MET 329 CG  
180 1 Y 1 E MET 331 ? SD  ? E MET 329 SD  
181 1 Y 1 E MET 331 ? CE  ? E MET 329 CE  
182 1 Y 1 E LEU 332 ? CG  ? E LEU 330 CG  
183 1 Y 1 E LEU 332 ? CD1 ? E LEU 330 CD1 
184 1 Y 1 E LEU 332 ? CD2 ? E LEU 330 CD2 
185 1 Y 1 E ILE 444 ? CG1 ? E ILE 649 CG1 
186 1 Y 1 E ILE 444 ? CG2 ? E ILE 649 CG2 
187 1 Y 1 E ILE 444 ? CD1 ? E ILE 649 CD1 
188 1 Y 1 E THR 446 ? OG1 ? E THR 651 OG1 
189 1 Y 1 E THR 446 ? CG2 ? E THR 651 CG2 
190 1 Y 1 E LYS 449 ? CG  ? E LYS 654 CG  
191 1 Y 1 E LYS 449 ? CD  ? E LYS 654 CD  
192 1 Y 1 E LYS 449 ? CE  ? E LYS 654 CE  
193 1 Y 1 E LYS 449 ? NZ  ? E LYS 654 NZ  
194 1 Y 1 E ARG 450 ? CG  ? E ARG 655 CG  
195 1 Y 1 E ARG 450 ? CD  ? E ARG 655 CD  
196 1 Y 1 E ARG 450 ? NE  ? E ARG 655 NE  
197 1 Y 1 E ARG 450 ? CZ  ? E ARG 655 CZ  
198 1 Y 1 E ARG 450 ? NH1 ? E ARG 655 NH1 
199 1 Y 1 E ARG 450 ? NH2 ? E ARG 655 NH2 
200 1 Y 1 E ILE 451 ? CG1 ? E ILE 656 CG1 
201 1 Y 1 E ILE 451 ? CG2 ? E ILE 656 CG2 
202 1 Y 1 E ILE 451 ? CD1 ? E ILE 656 CD1 
203 1 Y 1 E LEU 453 ? CG  ? E LEU 658 CG  
204 1 Y 1 E LEU 453 ? CD1 ? E LEU 658 CD1 
205 1 Y 1 E LEU 453 ? CD2 ? E LEU 658 CD2 
206 1 Y 1 E TYR 454 ? CG  ? E TYR 659 CG  
207 1 Y 1 E TYR 454 ? CD1 ? E TYR 659 CD1 
208 1 Y 1 E TYR 454 ? CD2 ? E TYR 659 CD2 
209 1 Y 1 E TYR 454 ? CE1 ? E TYR 659 CE1 
210 1 Y 1 E TYR 454 ? CE2 ? E TYR 659 CE2 
211 1 Y 1 E TYR 454 ? CZ  ? E TYR 659 CZ  
212 1 Y 1 E TYR 454 ? OH  ? E TYR 659 OH  
213 1 Y 1 E ARG 456 ? CG  ? E ARG 661 CG  
214 1 Y 1 E ARG 456 ? CD  ? E ARG 661 CD  
215 1 Y 1 E ARG 456 ? NE  ? E ARG 661 NE  
216 1 Y 1 E ARG 456 ? CZ  ? E ARG 661 CZ  
217 1 Y 1 E ARG 456 ? NH1 ? E ARG 661 NH1 
218 1 Y 1 E ARG 456 ? NH2 ? E ARG 661 NH2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BP0 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BP0 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BP0 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9BP0 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 14093 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.604 ? 19164 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 7.425 ? 2007  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.043 ? 2184  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003 ? 2398  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9BP0 
_struct.title                        'Cryo-EM structure of human heteromeric Glycine Receptor alpha3S346E-beta with glycine' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BP0 
_struct_keywords.text            
'glycine receptor subunit alpha-3, glycine receptor subunit beta, Green fluorescent protein, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 3 ? 
G N N 4 ? 
H N N 3 ? 
I N N 4 ? 
J N N 3 ? 
K N N 3 ? 
L N N 4 ? 
M N N 3 ? 
N N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GLRA3_HUMAN      O75311     ? 1 
;ARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD
DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFG
YTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWV
SFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRK
RKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISR
ACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
;
34  
2 UNP GLRB_HUMAN       P48167     ? 2 
;KSSKKGKGKKKQYLCPSQQSAEDLARVPANSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVN
IFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCP
LDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRR
QVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASL
VEYAVVQVMLN
;
25  
3 UNP A0A9X4KGN5_9BACI A0A9X4KGN5 ? 2 
;VSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTLTYGVQCFSRYPDHMKQ
HDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNYNSHNVYIMADKQKNG
IKVNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLLEFVTAAGITLGMDELYKSG

;
9   
4 UNP GLRB_HUMAN       P48167     ? 2 
;VGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKSQAKNNKKPPPAKPVIPTAAKRIDLYARA
LFPFCFLFFNVIYWSIYL
;
400 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9BP0 A 1   ? 422 ? O75311     34  ? 464 ? 1   431 
2 1 9BP0 B 1   ? 422 ? O75311     34  ? 464 ? 1   431 
3 1 9BP0 C 1   ? 422 ? O75311     34  ? 464 ? 1   431 
4 1 9BP0 D 1   ? 422 ? O75311     34  ? 464 ? 1   431 
5 2 9BP0 E 1   ? 331 ? P48167     25  ? 355 ? 3   333 
6 3 9BP0 E 339 H 578 M A0A9X4KGN5 9   ? 248 ? 333 342 
7 4 9BP0 E 583 R 680 ? P48167     400 ? 497 ? 342 475 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9BP0 ?   A ?   ? UNP O75311     ALA 362 deletion ?   1  
1 9BP0 ?   A ?   ? UNP O75311     LEU 363 deletion ?   2  
1 9BP0 ?   A ?   ? UNP O75311     GLU 364 deletion ?   3  
1 9BP0 ?   A ?   ? UNP O75311     LYS 365 deletion ?   4  
1 9BP0 ?   A ?   ? UNP O75311     PHE 366 deletion ?   5  
1 9BP0 ?   A ?   ? UNP O75311     TYR 367 deletion ?   6  
1 9BP0 ?   A ?   ? UNP O75311     ARG 368 deletion ?   7  
1 9BP0 ?   A ?   ? UNP O75311     PHE 369 deletion ?   8  
1 9BP0 ?   A ?   ? UNP O75311     SER 370 deletion ?   9  
1 9BP0 GLU A 337 ? UNP O75311     SER 379 conflict 346 10 
2 9BP0 ?   B ?   ? UNP O75311     ALA 362 deletion ?   11 
2 9BP0 ?   B ?   ? UNP O75311     LEU 363 deletion ?   12 
2 9BP0 ?   B ?   ? UNP O75311     GLU 364 deletion ?   13 
2 9BP0 ?   B ?   ? UNP O75311     LYS 365 deletion ?   14 
2 9BP0 ?   B ?   ? UNP O75311     PHE 366 deletion ?   15 
2 9BP0 ?   B ?   ? UNP O75311     TYR 367 deletion ?   16 
2 9BP0 ?   B ?   ? UNP O75311     ARG 368 deletion ?   17 
2 9BP0 ?   B ?   ? UNP O75311     PHE 369 deletion ?   18 
2 9BP0 ?   B ?   ? UNP O75311     SER 370 deletion ?   19 
2 9BP0 GLU B 337 ? UNP O75311     SER 379 conflict 346 20 
3 9BP0 ?   C ?   ? UNP O75311     ALA 362 deletion ?   21 
3 9BP0 ?   C ?   ? UNP O75311     LEU 363 deletion ?   22 
3 9BP0 ?   C ?   ? UNP O75311     GLU 364 deletion ?   23 
3 9BP0 ?   C ?   ? UNP O75311     LYS 365 deletion ?   24 
3 9BP0 ?   C ?   ? UNP O75311     PHE 366 deletion ?   25 
3 9BP0 ?   C ?   ? UNP O75311     TYR 367 deletion ?   26 
3 9BP0 ?   C ?   ? UNP O75311     ARG 368 deletion ?   27 
3 9BP0 ?   C ?   ? UNP O75311     PHE 369 deletion ?   28 
3 9BP0 ?   C ?   ? UNP O75311     SER 370 deletion ?   29 
3 9BP0 GLU C 337 ? UNP O75311     SER 379 conflict 346 30 
4 9BP0 ?   D ?   ? UNP O75311     ALA 362 deletion ?   31 
4 9BP0 ?   D ?   ? UNP O75311     LEU 363 deletion ?   32 
4 9BP0 ?   D ?   ? UNP O75311     GLU 364 deletion ?   33 
4 9BP0 ?   D ?   ? UNP O75311     LYS 365 deletion ?   34 
4 9BP0 ?   D ?   ? UNP O75311     PHE 366 deletion ?   35 
4 9BP0 ?   D ?   ? UNP O75311     TYR 367 deletion ?   36 
4 9BP0 ?   D ?   ? UNP O75311     ARG 368 deletion ?   37 
4 9BP0 ?   D ?   ? UNP O75311     PHE 369 deletion ?   38 
4 9BP0 ?   D ?   ? UNP O75311     SER 370 deletion ?   39 
4 9BP0 GLU D 337 ? UNP O75311     SER 379 conflict 346 40 
5 9BP0 GLY E 332 A UNP P48167     ?   ?   linker   333 41 
5 9BP0 GLY E 333 B UNP P48167     ?   ?   linker   333 42 
5 9BP0 SER E 334 C UNP P48167     ?   ?   linker   333 43 
5 9BP0 SER E 335 D UNP P48167     ?   ?   linker   333 44 
5 9BP0 ALA E 336 E UNP P48167     ?   ?   linker   333 45 
5 9BP0 ALA E 337 F UNP P48167     ?   ?   linker   333 46 
5 9BP0 ALA E 338 G UNP P48167     ?   ?   linker   333 47 
6 9BP0 PHE E 402 S UNP A0A9X4KGN5 LEU 72  conflict 335 48 
6 9BP0 SER E 403 T UNP A0A9X4KGN5 THR 73  conflict 335 49 
6 9BP0 HIS E 569 D UNP A0A9X4KGN5 LEU 239 conflict 342 50 
6 9BP0 SER E 579 N UNP A0A9X4KGN5 ?   ?   linker   342 51 
6 9BP0 GLY E 580 O UNP A0A9X4KGN5 ?   ?   linker   342 52 
6 9BP0 SER E 581 P UNP A0A9X4KGN5 ?   ?   linker   342 53 
6 9BP0 GLY E 582 Q UNP A0A9X4KGN5 ?   ?   linker   342 54 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 9   ? GLY A 19  ? SER A 9   GLY A 19  1 ? 11 
HELX_P HELX_P2  AA2 ARG A 20  ? GLY A 23  ? ARG A 20  GLY A 23  5 ? 4  
HELX_P HELX_P3  AA3 ASP A 70  ? ALA A 74  ? ASP A 70  ALA A 74  5 ? 5  
HELX_P HELX_P4  AA4 ASP A 86  ? ILE A 93  ? ASP A 86  ILE A 93  5 ? 8  
HELX_P HELX_P5  AA5 ASN A 144 ? MET A 147 ? ASN A 144 MET A 147 5 ? 4  
HELX_P HELX_P6  AA6 MET A 220 ? ILE A 244 ? MET A 220 ILE A 244 1 ? 25 
HELX_P HELX_P7  AA7 ALA A 248 ? SER A 273 ? ALA A 248 SER A 273 1 ? 26 
HELX_P HELX_P8  AA8 LYS A 281 ? ARG A 309 ? LYS A 281 ARG A 309 1 ? 29 
HELX_P HELX_P9  AA9 PHE A 379 ? ILE A 411 ? PHE A 388 ILE A 420 1 ? 33 
HELX_P HELX_P10 AB1 SER B 9   ? GLY B 19  ? SER B 9   GLY B 19  1 ? 11 
HELX_P HELX_P11 AB2 ARG B 20  ? GLY B 23  ? ARG B 20  GLY B 23  5 ? 4  
HELX_P HELX_P12 AB3 PRO B 71  ? ALA B 74  ? PRO B 71  ALA B 74  5 ? 4  
HELX_P HELX_P13 AB4 ASP B 86  ? SER B 92  ? ASP B 86  SER B 92  5 ? 7  
HELX_P HELX_P14 AB5 MET B 220 ? ILE B 244 ? MET B 220 ILE B 244 1 ? 25 
HELX_P HELX_P15 AB6 ALA B 248 ? SER B 273 ? ALA B 248 SER B 273 1 ? 26 
HELX_P HELX_P16 AB7 LYS B 281 ? ARG B 309 ? LYS B 281 ARG B 309 1 ? 29 
HELX_P HELX_P17 AB8 VAL B 378 ? ILE B 411 ? VAL B 387 ILE B 420 1 ? 34 
HELX_P HELX_P18 AB9 SER C 9   ? MET C 18  ? SER C 9   MET C 18  1 ? 10 
HELX_P HELX_P19 AC1 GLY C 19  ? GLY C 23  ? GLY C 19  GLY C 23  5 ? 5  
HELX_P HELX_P20 AC2 PRO C 71  ? ALA C 74  ? PRO C 71  ALA C 74  5 ? 4  
HELX_P HELX_P21 AC3 ASP C 86  ? ILE C 93  ? ASP C 86  ILE C 93  5 ? 8  
HELX_P HELX_P22 AC4 MET C 220 ? PHE C 242 ? MET C 220 PHE C 242 1 ? 23 
HELX_P HELX_P23 AC5 ALA C 248 ? SER C 273 ? ALA C 248 SER C 273 1 ? 26 
HELX_P HELX_P24 AC6 LYS C 281 ? ARG C 309 ? LYS C 281 ARG C 309 1 ? 29 
HELX_P HELX_P25 AC7 VAL C 378 ? ILE C 411 ? VAL C 387 ILE C 420 1 ? 34 
HELX_P HELX_P26 AC8 SER D 9   ? GLY D 19  ? SER D 9   GLY D 19  1 ? 11 
HELX_P HELX_P27 AC9 ASP D 70  ? ALA D 74  ? ASP D 70  ALA D 74  5 ? 5  
HELX_P HELX_P28 AD1 ASP D 86  ? ILE D 93  ? ASP D 86  ILE D 93  5 ? 8  
HELX_P HELX_P29 AD2 ASN D 144 ? MET D 147 ? ASN D 144 MET D 147 5 ? 4  
HELX_P HELX_P30 AD3 MET D 220 ? TRP D 243 ? MET D 220 TRP D 243 1 ? 24 
HELX_P HELX_P31 AD4 ALA D 248 ? ARG D 271 ? ALA D 248 ARG D 271 1 ? 24 
HELX_P HELX_P32 AD5 LYS D 281 ? ARG D 309 ? LYS D 281 ARG D 309 1 ? 29 
HELX_P HELX_P33 AD6 PHE D 379 ? ILE D 411 ? PHE D 388 ILE D 420 1 ? 33 
HELX_P HELX_P34 AD7 PRO E 28  ? ASN E 37  ? PRO E 30  ASN E 39  1 ? 10 
HELX_P HELX_P35 AD8 PRO E 90  ? LYS E 93  ? PRO E 92  LYS E 95  5 ? 4  
HELX_P HELX_P36 AD9 THR E 109 ? CYS E 113 ? THR E 111 CYS E 115 5 ? 5  
HELX_P HELX_P37 AE1 VAL E 242 ? MET E 247 ? VAL E 244 MET E 249 1 ? 6  
HELX_P HELX_P38 AE2 VAL E 249 ? ILE E 266 ? VAL E 251 ILE E 268 1 ? 18 
HELX_P HELX_P39 AE3 ALA E 270 ? GLU E 295 ? ALA E 272 GLU E 297 1 ? 26 
HELX_P HELX_P40 AE4 LYS E 303 ? ASN E 331 ? LYS E 305 ASN E 333 1 ? 29 
HELX_P HELX_P41 AE5 PRO E 650 ? LEU E 680 ? PRO E 445 LEU E 475 1 ? 31 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?   ? A CYS 138 SG  ? ? ? 1_555 A CYS 152 SG ? ? A CYS 138 A CYS 152 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf2  disulf ?   ? A CYS 198 SG  ? ? ? 1_555 A CYS 209 SG ? ? A CYS 198 A CYS 209 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf3  disulf ?   ? B CYS 138 SG  ? ? ? 1_555 B CYS 152 SG ? ? B CYS 138 B CYS 152 1_555 ? ? ? ? ? ? ? 2.034 ? ?               
disulf4  disulf ?   ? B CYS 198 SG  ? ? ? 1_555 B CYS 209 SG ? ? B CYS 198 B CYS 209 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf5  disulf ?   ? C CYS 138 SG  ? ? ? 1_555 C CYS 152 SG ? ? C CYS 138 C CYS 152 1_555 ? ? ? ? ? ? ? 2.035 ? ?               
disulf6  disulf ?   ? C CYS 198 SG  ? ? ? 1_555 C CYS 209 SG ? ? C CYS 198 C CYS 209 1_555 ? ? ? ? ? ? ? 2.030 ? ?               
disulf7  disulf ?   ? D CYS 138 SG  ? ? ? 1_555 D CYS 152 SG ? ? D CYS 138 D CYS 152 1_555 ? ? ? ? ? ? ? 2.035 ? ?               
disulf8  disulf ?   ? D CYS 198 SG  ? ? ? 1_555 D CYS 209 SG ? ? D CYS 198 D CYS 209 1_555 ? ? ? ? ? ? ? 2.028 ? ?               
disulf9  disulf ?   ? E CYS 159 SG  ? ? ? 1_555 E CYS 173 SG ? ? E CYS 161 E CYS 175 1_555 ? ? ? ? ? ? ? 2.033 ? ?               
disulf10 disulf ?   ? E CYS 219 SG  ? ? ? 1_555 E CYS 231 SG ? ? E CYS 221 E CYS 233 1_555 ? ? ? ? ? ? ? 2.031 ? ?               
covale1  covale one ? A ASN 38  ND2 ? ? ? 1_555 F NAG .   C1 ? ? A ASN 38  A NAG 501 1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
covale2  covale one ? B ASN 38  ND2 ? ? ? 1_555 H NAG .   C1 ? ? B ASN 38  B NAG 501 1_555 ? ? ? ? ? ? ? 1.448 ? N-Glycosylation 
covale3  covale one ? C ASN 38  ND2 ? ? ? 1_555 J NAG .   C1 ? ? C ASN 38  C NAG 501 1_555 ? ? ? ? ? ? ? 1.443 ? N-Glycosylation 
covale4  covale one ? D ASN 38  ND2 ? ? ? 1_555 K NAG .   C1 ? ? D ASN 38  D NAG 501 1_555 ? ? ? ? ? ? ? 1.445 ? N-Glycosylation 
covale5  covale one ? E ASN 218 ND2 ? ? ? 1_555 M NAG .   C1 ? ? E ASN 220 E NAG 501 1_555 ? ? ? ? ? ? ? 1.444 ? N-Glycosylation 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG F .   ? ASN A 38  ? NAG A 501 ? 1_555 ASN A 38  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG H .   ? ASN B 38  ? NAG B 501 ? 1_555 ASN B 38  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG J .   ? ASN C 38  ? NAG C 501 ? 1_555 ASN C 38  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  NAG K .   ? ASN D 38  ? NAG D 501 ? 1_555 ASN D 38  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
5  NAG M .   ? ASN E 218 ? NAG E 501 ? 1_555 ASN E 220 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
6  CYS A 138 ? CYS A 152 ? CYS A 138 ? 1_555 CYS A 152 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7  CYS A 198 ? CYS A 209 ? CYS A 198 ? 1_555 CYS A 209 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8  CYS B 138 ? CYS B 152 ? CYS B 138 ? 1_555 CYS B 152 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9  CYS B 198 ? CYS B 209 ? CYS B 198 ? 1_555 CYS B 209 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS C 138 ? CYS C 152 ? CYS C 138 ? 1_555 CYS C 152 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
11 CYS C 198 ? CYS C 209 ? CYS C 198 ? 1_555 CYS C 209 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
12 CYS D 138 ? CYS D 152 ? CYS D 138 ? 1_555 CYS D 152 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
13 CYS D 198 ? CYS D 209 ? CYS D 198 ? 1_555 CYS D 209 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
14 CYS E 159 ? CYS E 173 ? CYS E 161 ? 1_555 CYS E 175 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
15 CYS E 219 ? CYS E 231 ? CYS E 221 ? 1_555 CYS E 233 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 4 ? 
AA3 ? 6 ? 
AA4 ? 4 ? 
AA5 ? 2 ? 
AA6 ? 6 ? 
AA7 ? 5 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 2 ? 
AB2 ? 4 ? 
AB3 ? 6 ? 
AB4 ? 4 ? 
AB5 ? 2 ? 
AB6 ? 6 ? 
AB7 ? 5 ? 
AB8 ? 4 ? 
AB9 ? 4 ? 
AC1 ? 2 ? 
AC2 ? 6 ? 
AC3 ? 5 ? 
AC4 ? 2 ? 
AC5 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA6 5 6 ? parallel      
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? parallel      
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB3 5 6 ? parallel      
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB6 4 5 ? anti-parallel 
AB6 5 6 ? parallel      
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB7 4 5 ? parallel      
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC2 4 5 ? anti-parallel 
AC2 5 6 ? parallel      
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
AC3 4 5 ? parallel      
AC4 1 2 ? anti-parallel 
AC5 1 2 ? anti-parallel 
AC5 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 37  ? THR A 40  ? VAL A 37  THR A 40  
AA1 2 LEU A 166 ? GLU A 169 ? LEU A 166 GLU A 169 
AA2 1 LEU A 83  ? LEU A 85  ? LEU A 83  LEU A 85  
AA2 2 LYS A 116 ? ILE A 120 ? LYS A 116 ILE A 120 
AA2 3 VAL A 126 ? LEU A 136 ? VAL A 126 LEU A 136 
AA2 4 GLU A 103 ? ASN A 107 ? GLU A 103 ASN A 107 
AA3 1 LEU A 83  ? LEU A 85  ? LEU A 83  LEU A 85  
AA3 2 LYS A 116 ? ILE A 120 ? LYS A 116 ILE A 120 
AA3 3 VAL A 126 ? LEU A 136 ? VAL A 126 LEU A 136 
AA3 4 ASP A 57  ? TRP A 68  ? ASP A 57  TRP A 68  
AA3 5 ASN A 42  ? ALA A 52  ? ASN A 42  ALA A 52  
AA3 6 VAL A 176 ? VAL A 178 ? VAL A 176 VAL A 178 
AA4 1 PHE A 99  ? PHE A 100 ? PHE A 99  PHE A 100 
AA4 2 VAL A 149 ? GLU A 157 ? VAL A 149 GLU A 157 
AA4 3 CYS A 209 ? ARG A 218 ? CYS A 209 ARG A 218 
AA4 4 PHE A 187 ? ARG A 196 ? PHE A 187 ARG A 196 
AA5 1 HIS A 201 ? TYR A 202 ? HIS A 201 TYR A 202 
AA5 2 GLY A 205 ? LYS A 206 ? GLY A 205 LYS A 206 
AA6 1 LEU B 83  ? LEU B 85  ? LEU B 83  LEU B 85  
AA6 2 LYS B 116 ? ILE B 120 ? LYS B 116 ILE B 120 
AA6 3 ASN B 125 ? LEU B 134 ? ASN B 125 LEU B 134 
AA6 4 ASP B 57  ? ASN B 69  ? ASP B 57  ASN B 69  
AA6 5 VAL B 37  ? ALA B 52  ? VAL B 37  ALA B 52  
AA6 6 LEU B 166 ? GLU B 169 ? LEU B 166 GLU B 169 
AA7 1 ALA B 106 ? ASN B 107 ? ALA B 106 ASN B 107 
AA7 2 ASN B 125 ? LEU B 134 ? ASN B 125 LEU B 134 
AA7 3 ASP B 57  ? ASN B 69  ? ASP B 57  ASN B 69  
AA7 4 VAL B 37  ? ALA B 52  ? VAL B 37  ALA B 52  
AA7 5 VAL B 176 ? VAL B 178 ? VAL B 176 VAL B 178 
AA8 1 PHE B 99  ? PHE B 100 ? PHE B 99  PHE B 100 
AA8 2 VAL B 149 ? GLU B 157 ? VAL B 149 GLU B 157 
AA8 3 CYS B 209 ? GLU B 217 ? CYS B 209 GLU B 217 
AA8 4 LEU B 188 ? LEU B 189 ? LEU B 188 LEU B 189 
AA9 1 PHE B 99  ? PHE B 100 ? PHE B 99  PHE B 100 
AA9 2 VAL B 149 ? GLU B 157 ? VAL B 149 GLU B 157 
AA9 3 CYS B 209 ? GLU B 217 ? CYS B 209 GLU B 217 
AA9 4 ASP B 194 ? ARG B 196 ? ASP B 194 ARG B 196 
AB1 1 VAL C 37  ? THR C 40  ? VAL C 37  THR C 40  
AB1 2 LEU C 166 ? GLU C 169 ? LEU C 166 GLU C 169 
AB2 1 LEU C 83  ? LEU C 85  ? LEU C 83  LEU C 85  
AB2 2 LYS C 116 ? ILE C 120 ? LYS C 116 ILE C 120 
AB2 3 ASN C 125 ? LEU C 136 ? ASN C 125 LEU C 136 
AB2 4 ALA C 106 ? ASN C 107 ? ALA C 106 ASN C 107 
AB3 1 LEU C 83  ? LEU C 85  ? LEU C 83  LEU C 85  
AB3 2 LYS C 116 ? ILE C 120 ? LYS C 116 ILE C 120 
AB3 3 ASN C 125 ? LEU C 136 ? ASN C 125 LEU C 136 
AB3 4 ASP C 57  ? ASN C 69  ? ASP C 57  ASN C 69  
AB3 5 ILE C 43  ? ALA C 52  ? ILE C 43  ALA C 52  
AB3 6 VAL C 176 ? VAL C 178 ? VAL C 176 VAL C 178 
AB4 1 PHE C 99  ? PHE C 100 ? PHE C 99  PHE C 100 
AB4 2 VAL C 149 ? GLU C 157 ? VAL C 149 GLU C 157 
AB4 3 CYS C 209 ? ARG C 218 ? CYS C 209 ARG C 218 
AB4 4 PHE C 187 ? TYR C 197 ? PHE C 187 TYR C 197 
AB5 1 HIS C 201 ? TYR C 202 ? HIS C 201 TYR C 202 
AB5 2 GLY C 205 ? LYS C 206 ? GLY C 205 LYS C 206 
AB6 1 LEU D 83  ? LEU D 85  ? LEU D 83  LEU D 85  
AB6 2 LYS D 116 ? ILE D 120 ? LYS D 116 ILE D 120 
AB6 3 VAL D 126 ? LEU D 136 ? VAL D 126 LEU D 136 
AB6 4 ASP D 57  ? TRP D 68  ? ASP D 57  TRP D 68  
AB6 5 VAL D 37  ? ALA D 52  ? VAL D 37  ALA D 52  
AB6 6 LEU D 166 ? TRP D 170 ? LEU D 166 TRP D 170 
AB7 1 ALA D 106 ? ASN D 107 ? ALA D 106 ASN D 107 
AB7 2 VAL D 126 ? LEU D 136 ? VAL D 126 LEU D 136 
AB7 3 ASP D 57  ? TRP D 68  ? ASP D 57  TRP D 68  
AB7 4 VAL D 37  ? ALA D 52  ? VAL D 37  ALA D 52  
AB7 5 VAL D 176 ? VAL D 178 ? VAL D 176 VAL D 178 
AB8 1 PHE D 99  ? PHE D 100 ? PHE D 99  PHE D 100 
AB8 2 VAL D 149 ? GLU D 157 ? VAL D 149 GLU D 157 
AB8 3 CYS D 209 ? ARG D 218 ? CYS D 209 ARG D 218 
AB8 4 PHE D 187 ? LEU D 189 ? PHE D 187 LEU D 189 
AB9 1 PHE D 99  ? PHE D 100 ? PHE D 99  PHE D 100 
AB9 2 VAL D 149 ? GLU D 157 ? VAL D 149 GLU D 157 
AB9 3 CYS D 209 ? ARG D 218 ? CYS D 209 ARG D 218 
AB9 4 ASP D 194 ? ARG D 196 ? ASP D 194 ARG D 196 
AC1 1 HIS D 201 ? TYR D 202 ? HIS D 201 TYR D 202 
AC1 2 GLY D 205 ? LYS D 206 ? GLY D 205 LYS D 206 
AC2 1 ALA E 103 ? THR E 105 ? ALA E 105 THR E 107 
AC2 2 ILE E 137 ? PHE E 142 ? ILE E 139 PHE E 144 
AC2 3 ASP E 146 ? SER E 158 ? ASP E 148 SER E 160 
AC2 4 ASP E 76  ? ASN E 88  ? ASP E 78  ASN E 90  
AC2 5 VAL E 56  ? GLN E 71  ? VAL E 58  GLN E 73  
AC2 6 LEU E 187 ? TRP E 191 ? LEU E 189 TRP E 193 
AC3 1 SER E 126 ? ALA E 127 ? SER E 128 ALA E 129 
AC3 2 ASP E 146 ? SER E 158 ? ASP E 148 SER E 160 
AC3 3 ASP E 76  ? ASN E 88  ? ASP E 78  ASN E 90  
AC3 4 VAL E 56  ? GLN E 71  ? VAL E 58  GLN E 73  
AC3 5 VAL E 197 ? LEU E 199 ? VAL E 199 LEU E 201 
AC4 1 PHE E 120 ? PHE E 121 ? PHE E 122 PHE E 123 
AC4 2 LEU E 177 ? GLU E 178 ? LEU E 179 GLU E 180 
AC5 1 THR E 170 ? MET E 175 ? THR E 172 MET E 177 
AC5 2 VAL E 232 ? ARG E 240 ? VAL E 234 ARG E 242 
AC5 3 PHE E 207 ? ASN E 218 ? PHE E 209 ASN E 220 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 39  ? N VAL A 39  O ILE A 167 ? O ILE A 167 
AA2 1 2 O LEU A 83  ? O LEU A 83  N ILE A 120 ? N ILE A 120 
AA2 2 3 N ARG A 119 ? N ARG A 119 O LEU A 127 ? O LEU A 127 
AA2 3 4 O THR A 135 ? O THR A 135 N GLY A 105 ? N GLY A 105 
AA3 1 2 O LEU A 83  ? O LEU A 83  N ILE A 120 ? N ILE A 120 
AA3 2 3 N ARG A 119 ? N ARG A 119 O LEU A 127 ? O LEU A 127 
AA3 3 4 O LEU A 136 ? O LEU A 136 N TYR A 58  ? N TYR A 58  
AA3 4 5 O PHE A 63  ? O PHE A 63  N PHE A 44  ? N PHE A 44  
AA3 5 6 N ILE A 45  ? N ILE A 45  O GLN A 177 ? O GLN A 177 
AA4 1 2 N PHE A 99  ? N PHE A 99  O GLU A 157 ? O GLU A 157 
AA4 2 3 N LEU A 156 ? N LEU A 156 O ILE A 210 ? O ILE A 210 
AA4 3 4 O GLU A 211 ? O GLU A 211 N ARG A 196 ? N ARG A 196 
AA5 1 2 N TYR A 202 ? N TYR A 202 O GLY A 205 ? O GLY A 205 
AA6 1 2 N LEU B 83  ? N LEU B 83  O ILE B 120 ? O ILE B 120 
AA6 2 3 N LEU B 117 ? N LEU B 117 O SER B 129 ? O SER B 129 
AA6 3 4 O ILE B 130 ? O ILE B 130 N LEU B 64  ? N LEU B 64  
AA6 4 5 O PHE B 63  ? O PHE B 63  N PHE B 44  ? N PHE B 44  
AA6 5 6 N VAL B 39  ? N VAL B 39  O ILE B 167 ? O ILE B 167 
AA7 1 2 N ASN B 107 ? N ASN B 107 O THR B 133 ? O THR B 133 
AA7 2 3 O ILE B 130 ? O ILE B 130 N LEU B 64  ? N LEU B 64  
AA7 3 4 O PHE B 63  ? O PHE B 63  N PHE B 44  ? N PHE B 44  
AA7 4 5 N ILE B 45  ? N ILE B 45  O GLN B 177 ? O GLN B 177 
AA8 1 2 N PHE B 99  ? N PHE B 99  O GLU B 157 ? O GLU B 157 
AA8 2 3 N LEU B 156 ? N LEU B 156 O ILE B 210 ? O ILE B 210 
AA8 3 4 O GLU B 217 ? O GLU B 217 N LEU B 188 ? N LEU B 188 
AA9 1 2 N PHE B 99  ? N PHE B 99  O GLU B 157 ? O GLU B 157 
AA9 2 3 N LEU B 156 ? N LEU B 156 O ILE B 210 ? O ILE B 210 
AA9 3 4 O GLU B 211 ? O GLU B 211 N ARG B 196 ? N ARG B 196 
AB1 1 2 N VAL C 39  ? N VAL C 39  O ILE C 167 ? O ILE C 167 
AB2 1 2 N LEU C 85  ? N LEU C 85  O LEU C 118 ? O LEU C 118 
AB2 2 3 N ARG C 119 ? N ARG C 119 O LEU C 127 ? O LEU C 127 
AB2 3 4 O THR C 133 ? O THR C 133 N ASN C 107 ? N ASN C 107 
AB3 1 2 N LEU C 85  ? N LEU C 85  O LEU C 118 ? O LEU C 118 
AB3 2 3 N ARG C 119 ? N ARG C 119 O LEU C 127 ? O LEU C 127 
AB3 3 4 O LEU C 136 ? O LEU C 136 N TYR C 58  ? N TYR C 58  
AB3 4 5 O ASN C 61  ? O ASN C 61  N ASN C 46  ? N ASN C 46  
AB3 5 6 N ILE C 45  ? N ILE C 45  O GLN C 177 ? O GLN C 177 
AB4 1 2 N PHE C 99  ? N PHE C 99  O GLU C 157 ? O GLU C 157 
AB4 2 3 N LEU C 156 ? N LEU C 156 O ILE C 210 ? O ILE C 210 
AB4 3 4 O ARG C 213 ? O ARG C 213 N ASP C 194 ? N ASP C 194 
AB5 1 2 N TYR C 202 ? N TYR C 202 O GLY C 205 ? O GLY C 205 
AB6 1 2 N LEU D 85  ? N LEU D 85  O LEU D 118 ? O LEU D 118 
AB6 2 3 N ARG D 119 ? N ARG D 119 O LEU D 127 ? O LEU D 127 
AB6 3 4 O TYR D 128 ? O TYR D 128 N GLN D 66  ? N GLN D 66  
AB6 4 5 O PHE D 63  ? O PHE D 63  N PHE D 44  ? N PHE D 44  
AB6 5 6 N VAL D 39  ? N VAL D 39  O ILE D 167 ? O ILE D 167 
AB7 1 2 N ASN D 107 ? N ASN D 107 O THR D 133 ? O THR D 133 
AB7 2 3 O TYR D 128 ? O TYR D 128 N GLN D 66  ? N GLN D 66  
AB7 3 4 O PHE D 63  ? O PHE D 63  N PHE D 44  ? N PHE D 44  
AB7 4 5 N ILE D 45  ? N ILE D 45  O GLN D 177 ? O GLN D 177 
AB8 1 2 N PHE D 99  ? N PHE D 99  O GLU D 157 ? O GLU D 157 
AB8 2 3 N LEU D 156 ? N LEU D 156 O ILE D 210 ? O ILE D 210 
AB8 3 4 O GLU D 217 ? O GLU D 217 N LEU D 188 ? N LEU D 188 
AB9 1 2 N PHE D 99  ? N PHE D 99  O GLU D 157 ? O GLU D 157 
AB9 2 3 N LEU D 156 ? N LEU D 156 O ILE D 210 ? O ILE D 210 
AB9 3 4 O GLU D 211 ? O GLU D 211 N ARG D 196 ? N ARG D 196 
AC1 1 2 N TYR D 202 ? N TYR D 202 O GLY D 205 ? O GLY D 205 
AC2 1 2 N LEU E 104 ? N LEU E 106 O ILE E 141 ? O ILE E 143 
AC2 2 3 N LEU E 138 ? N LEU E 140 O SER E 150 ? O SER E 152 
AC2 3 4 O VAL E 149 ? O VAL E 151 N GLN E 85  ? N GLN E 87  
AC2 4 5 O ARG E 84  ? O ARG E 86  N ASN E 61  ? N ASN E 63  
AC2 5 6 N VAL E 58  ? N VAL E 60  O ARG E 188 ? O ARG E 190 
AC3 1 2 N SER E 126 ? N SER E 128 O THR E 156 ? O THR E 158 
AC3 2 3 O VAL E 149 ? O VAL E 151 N GLN E 85  ? N GLN E 87  
AC3 3 4 O ARG E 84  ? O ARG E 86  N ASN E 61  ? N ASN E 63  
AC3 4 5 N ILE E 64  ? N ILE E 66  O GLN E 198 ? O GLN E 200 
AC4 1 2 N PHE E 120 ? N PHE E 122 O GLU E 178 ? O GLU E 180 
AC5 1 2 N MET E 175 ? N MET E 177 O VAL E 234 ? O VAL E 236 
AC5 2 3 O ILE E 235 ? O ILE E 237 N GLU E 215 ? N GLU E 217 
# 
_pdbx_entry_details.entry_id                   9BP0 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   O 
_pdbx_validate_close_contact.auth_asym_id_1   D 
_pdbx_validate_close_contact.auth_comp_id_1   LEU 
_pdbx_validate_close_contact.auth_seq_id_1    98 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OG1 
_pdbx_validate_close_contact.auth_asym_id_2   E 
_pdbx_validate_close_contact.auth_comp_id_2   THR 
_pdbx_validate_close_contact.auth_seq_id_2    135 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.13 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 MET A 18  ? ? -140.53 13.07   
2  1 PHE A 63  ? ? -101.18 76.63   
3  1 ASN A 102 ? ? -91.76  53.98   
4  1 THR A 112 ? ? 70.26   -9.95   
5  1 THR A 113 ? ? -173.60 -173.74 
6  1 ALA A 174 ? ? 52.41   70.78   
7  1 THR A 199 ? ? 35.91   54.68   
8  1 MET A 227 ? ? -130.15 -37.06  
9  1 TYR A 279 ? ? -79.74  -169.09 
10 1 ILE A 420 ? ? -126.40 -52.62  
11 1 THR B 112 ? ? 66.16   -8.07   
12 1 THR B 113 ? ? -174.00 -173.63 
13 1 GLN B 186 ? ? -141.30 32.40   
14 1 THR B 199 ? ? 36.10   57.69   
15 1 VAL B 387 ? ? 35.97   33.77   
16 1 ILE B 420 ? ? -120.72 -52.83  
17 1 THR C 112 ? ? 66.05   -6.89   
18 1 THR C 135 ? ? -100.63 75.84   
19 1 VAL C 387 ? ? 33.63   44.68   
20 1 THR D 112 ? ? 67.68   -7.89   
21 1 THR D 113 ? ? 178.92  173.34  
22 1 THR D 199 ? ? 36.09   58.29   
23 1 MET D 227 ? ? -130.82 -38.42  
24 1 ALA D 248 ? ? -93.22  55.39   
25 1 VAL D 387 ? ? 42.05   26.95   
26 1 GLU D 424 ? ? 65.88   170.71  
27 1 THR E 135 ? ? 67.34   -6.56   
28 1 ASP E 197 ? ? 52.86   71.12   
29 1 ASP E 271 ? ? 47.74   27.04   
# 
_space_group_symop.id              1 
_space_group_symop.operation_xyz   x,y,z 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9BP0 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  8DN4 
_em_3d_fitting_list.pdb_chain_id                  ? 
_em_3d_fitting_list.pdb_chain_residue_range       ? 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   PDB 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                8DN4 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    9BP0 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.67 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               9628 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'heteromeric glycine receptor alpha3S346E and beta with glycine' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        9BP0 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'GATAN LIQUID NITROGEN' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             BASIC 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    ? 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9BP0 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9BP0 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A ALA 1   ? A ALA 1   
2   1 Y 1 A ARG 2   ? A ARG 2   
3   1 Y 1 A SER 3   ? A SER 3   
4   1 Y 1 A ARG 4   ? A ARG 4   
5   1 Y 1 A SER 5   ? A SER 5   
6   1 Y 1 A ALA 6   ? A ALA 6   
7   1 Y 1 A PRO 7   ? A PRO 7   
8   1 Y 1 A HIS 320 ? A HIS 311 
9   1 Y 1 A LYS 321 ? A LYS 312 
10  1 Y 1 A GLU 322 ? A GLU 313 
11  1 Y 1 A LEU 323 ? A LEU 314 
12  1 Y 1 A LEU 324 ? A LEU 315 
13  1 Y 1 A ARG 325 ? A ARG 316 
14  1 Y 1 A PHE 326 ? A PHE 317 
15  1 Y 1 A ARG 327 ? A ARG 318 
16  1 Y 1 A ARG 328 ? A ARG 319 
17  1 Y 1 A LYS 329 ? A LYS 320 
18  1 Y 1 A ARG 330 ? A ARG 321 
19  1 Y 1 A LYS 331 ? A LYS 322 
20  1 Y 1 A ASN 332 ? A ASN 323 
21  1 Y 1 A LYS 333 ? A LYS 324 
22  1 Y 1 A THR 334 ? A THR 325 
23  1 Y 1 A GLU 335 ? A GLU 326 
24  1 Y 1 A ALA 336 ? A ALA 327 
25  1 Y 1 A PHE 337 ? A PHE 328 
26  1 Y 1 A ASP 338 ? A ASP 329 
27  1 Y 1 A MET 339 ? A MET 330 
28  1 Y 1 A ASP 340 ? A ASP 331 
29  1 Y 1 A ASP 341 ? A ASP 332 
30  1 Y 1 A GLU 342 ? A GLU 333 
31  1 Y 1 A VAL 343 ? A VAL 334 
32  1 Y 1 A ARG 344 ? A ARG 335 
33  1 Y 1 A GLU 345 ? A GLU 336 
34  1 Y 1 A GLU 346 ? A GLU 337 
35  1 Y 1 A ARG 347 ? A ARG 338 
36  1 Y 1 A PHE 348 ? A PHE 339 
37  1 Y 1 A SER 349 ? A SER 340 
38  1 Y 1 A PHE 350 ? A PHE 341 
39  1 Y 1 A THR 351 ? A THR 342 
40  1 Y 1 A ALA 352 ? A ALA 343 
41  1 Y 1 A TYR 353 ? A TYR 344 
42  1 Y 1 A GLY 354 ? A GLY 345 
43  1 Y 1 A MET 355 ? A MET 346 
44  1 Y 1 A GLY 356 ? A GLY 347 
45  1 Y 1 A PRO 357 ? A PRO 348 
46  1 Y 1 A CYS 358 ? A CYS 349 
47  1 Y 1 A LEU 359 ? A LEU 350 
48  1 Y 1 A GLN 360 ? A GLN 351 
49  1 Y 1 A ALA 361 ? A ALA 352 
50  1 Y 1 A LYS 362 ? A LYS 353 
51  1 Y 1 A ASP 363 ? A ASP 354 
52  1 Y 1 A GLY 364 ? A GLY 355 
53  1 Y 1 A MET 365 ? A MET 356 
54  1 Y 1 A THR 366 ? A THR 357 
55  1 Y 1 A PRO 367 ? A PRO 358 
56  1 Y 1 A LYS 368 ? A LYS 359 
57  1 Y 1 A GLY 369 ? A GLY 360 
58  1 Y 1 A PRO 370 ? A PRO 361 
59  1 Y 1 A ASN 371 ? A ASN 362 
60  1 Y 1 A HIS 372 ? A HIS 363 
61  1 Y 1 A PRO 373 ? A PRO 364 
62  1 Y 1 A VAL 374 ? A VAL 365 
63  1 Y 1 A GLN 375 ? A GLN 366 
64  1 Y 1 A VAL 376 ? A VAL 367 
65  1 Y 1 A MET 377 ? A MET 368 
66  1 Y 1 A PRO 378 ? A PRO 369 
67  1 Y 1 A LYS 379 ? A LYS 370 
68  1 Y 1 A SER 380 ? A SER 371 
69  1 Y 1 A PRO 381 ? A PRO 372 
70  1 Y 1 A ASP 382 ? A ASP 373 
71  1 Y 1 A GLU 383 ? A GLU 374 
72  1 Y 1 A MET 384 ? A MET 375 
73  1 Y 1 A ARG 385 ? A ARG 376 
74  1 Y 1 A ASP 425 ? A ASP 416 
75  1 Y 1 A ILE 426 ? A ILE 417 
76  1 Y 1 A HIS 427 ? A HIS 418 
77  1 Y 1 A GLN 428 ? A GLN 419 
78  1 Y 1 A GLN 429 ? A GLN 420 
79  1 Y 1 A GLN 430 ? A GLN 421 
80  1 Y 1 A ASP 431 ? A ASP 422 
81  1 Y 1 B ALA 1   ? B ALA 1   
82  1 Y 1 B ARG 2   ? B ARG 2   
83  1 Y 1 B SER 3   ? B SER 3   
84  1 Y 1 B ARG 4   ? B ARG 4   
85  1 Y 1 B SER 5   ? B SER 5   
86  1 Y 1 B ALA 6   ? B ALA 6   
87  1 Y 1 B PRO 7   ? B PRO 7   
88  1 Y 1 B HIS 320 ? B HIS 311 
89  1 Y 1 B LYS 321 ? B LYS 312 
90  1 Y 1 B GLU 322 ? B GLU 313 
91  1 Y 1 B LEU 323 ? B LEU 314 
92  1 Y 1 B LEU 324 ? B LEU 315 
93  1 Y 1 B ARG 325 ? B ARG 316 
94  1 Y 1 B PHE 326 ? B PHE 317 
95  1 Y 1 B ARG 327 ? B ARG 318 
96  1 Y 1 B ARG 328 ? B ARG 319 
97  1 Y 1 B LYS 329 ? B LYS 320 
98  1 Y 1 B ARG 330 ? B ARG 321 
99  1 Y 1 B LYS 331 ? B LYS 322 
100 1 Y 1 B ASN 332 ? B ASN 323 
101 1 Y 1 B LYS 333 ? B LYS 324 
102 1 Y 1 B THR 334 ? B THR 325 
103 1 Y 1 B GLU 335 ? B GLU 326 
104 1 Y 1 B ALA 336 ? B ALA 327 
105 1 Y 1 B PHE 337 ? B PHE 328 
106 1 Y 1 B ASP 338 ? B ASP 329 
107 1 Y 1 B MET 339 ? B MET 330 
108 1 Y 1 B ASP 340 ? B ASP 331 
109 1 Y 1 B ASP 341 ? B ASP 332 
110 1 Y 1 B GLU 342 ? B GLU 333 
111 1 Y 1 B VAL 343 ? B VAL 334 
112 1 Y 1 B ARG 344 ? B ARG 335 
113 1 Y 1 B GLU 345 ? B GLU 336 
114 1 Y 1 B GLU 346 ? B GLU 337 
115 1 Y 1 B ARG 347 ? B ARG 338 
116 1 Y 1 B PHE 348 ? B PHE 339 
117 1 Y 1 B SER 349 ? B SER 340 
118 1 Y 1 B PHE 350 ? B PHE 341 
119 1 Y 1 B THR 351 ? B THR 342 
120 1 Y 1 B ALA 352 ? B ALA 343 
121 1 Y 1 B TYR 353 ? B TYR 344 
122 1 Y 1 B GLY 354 ? B GLY 345 
123 1 Y 1 B MET 355 ? B MET 346 
124 1 Y 1 B GLY 356 ? B GLY 347 
125 1 Y 1 B PRO 357 ? B PRO 348 
126 1 Y 1 B CYS 358 ? B CYS 349 
127 1 Y 1 B LEU 359 ? B LEU 350 
128 1 Y 1 B GLN 360 ? B GLN 351 
129 1 Y 1 B ALA 361 ? B ALA 352 
130 1 Y 1 B LYS 362 ? B LYS 353 
131 1 Y 1 B ASP 363 ? B ASP 354 
132 1 Y 1 B GLY 364 ? B GLY 355 
133 1 Y 1 B MET 365 ? B MET 356 
134 1 Y 1 B THR 366 ? B THR 357 
135 1 Y 1 B PRO 367 ? B PRO 358 
136 1 Y 1 B LYS 368 ? B LYS 359 
137 1 Y 1 B GLY 369 ? B GLY 360 
138 1 Y 1 B PRO 370 ? B PRO 361 
139 1 Y 1 B ASN 371 ? B ASN 362 
140 1 Y 1 B HIS 372 ? B HIS 363 
141 1 Y 1 B PRO 373 ? B PRO 364 
142 1 Y 1 B VAL 374 ? B VAL 365 
143 1 Y 1 B GLN 375 ? B GLN 366 
144 1 Y 1 B VAL 376 ? B VAL 367 
145 1 Y 1 B MET 377 ? B MET 368 
146 1 Y 1 B PRO 378 ? B PRO 369 
147 1 Y 1 B LYS 379 ? B LYS 370 
148 1 Y 1 B SER 380 ? B SER 371 
149 1 Y 1 B PRO 381 ? B PRO 372 
150 1 Y 1 B ASP 382 ? B ASP 373 
151 1 Y 1 B GLU 383 ? B GLU 374 
152 1 Y 1 B MET 384 ? B MET 375 
153 1 Y 1 B HIS 423 ? B HIS 414 
154 1 Y 1 B GLU 424 ? B GLU 415 
155 1 Y 1 B ASP 425 ? B ASP 416 
156 1 Y 1 B ILE 426 ? B ILE 417 
157 1 Y 1 B HIS 427 ? B HIS 418 
158 1 Y 1 B GLN 428 ? B GLN 419 
159 1 Y 1 B GLN 429 ? B GLN 420 
160 1 Y 1 B GLN 430 ? B GLN 421 
161 1 Y 1 B ASP 431 ? B ASP 422 
162 1 Y 1 C ALA 1   ? C ALA 1   
163 1 Y 1 C ARG 2   ? C ARG 2   
164 1 Y 1 C SER 3   ? C SER 3   
165 1 Y 1 C ARG 4   ? C ARG 4   
166 1 Y 1 C SER 5   ? C SER 5   
167 1 Y 1 C ALA 6   ? C ALA 6   
168 1 Y 1 C PRO 7   ? C PRO 7   
169 1 Y 1 C HIS 320 ? C HIS 311 
170 1 Y 1 C LYS 321 ? C LYS 312 
171 1 Y 1 C GLU 322 ? C GLU 313 
172 1 Y 1 C LEU 323 ? C LEU 314 
173 1 Y 1 C LEU 324 ? C LEU 315 
174 1 Y 1 C ARG 325 ? C ARG 316 
175 1 Y 1 C PHE 326 ? C PHE 317 
176 1 Y 1 C ARG 327 ? C ARG 318 
177 1 Y 1 C ARG 328 ? C ARG 319 
178 1 Y 1 C LYS 329 ? C LYS 320 
179 1 Y 1 C ARG 330 ? C ARG 321 
180 1 Y 1 C LYS 331 ? C LYS 322 
181 1 Y 1 C ASN 332 ? C ASN 323 
182 1 Y 1 C LYS 333 ? C LYS 324 
183 1 Y 1 C THR 334 ? C THR 325 
184 1 Y 1 C GLU 335 ? C GLU 326 
185 1 Y 1 C ALA 336 ? C ALA 327 
186 1 Y 1 C PHE 337 ? C PHE 328 
187 1 Y 1 C ASP 338 ? C ASP 329 
188 1 Y 1 C MET 339 ? C MET 330 
189 1 Y 1 C ASP 340 ? C ASP 331 
190 1 Y 1 C ASP 341 ? C ASP 332 
191 1 Y 1 C GLU 342 ? C GLU 333 
192 1 Y 1 C VAL 343 ? C VAL 334 
193 1 Y 1 C ARG 344 ? C ARG 335 
194 1 Y 1 C GLU 345 ? C GLU 336 
195 1 Y 1 C GLU 346 ? C GLU 337 
196 1 Y 1 C ARG 347 ? C ARG 338 
197 1 Y 1 C PHE 348 ? C PHE 339 
198 1 Y 1 C SER 349 ? C SER 340 
199 1 Y 1 C PHE 350 ? C PHE 341 
200 1 Y 1 C THR 351 ? C THR 342 
201 1 Y 1 C ALA 352 ? C ALA 343 
202 1 Y 1 C TYR 353 ? C TYR 344 
203 1 Y 1 C GLY 354 ? C GLY 345 
204 1 Y 1 C MET 355 ? C MET 346 
205 1 Y 1 C GLY 356 ? C GLY 347 
206 1 Y 1 C PRO 357 ? C PRO 348 
207 1 Y 1 C CYS 358 ? C CYS 349 
208 1 Y 1 C LEU 359 ? C LEU 350 
209 1 Y 1 C GLN 360 ? C GLN 351 
210 1 Y 1 C ALA 361 ? C ALA 352 
211 1 Y 1 C LYS 362 ? C LYS 353 
212 1 Y 1 C ASP 363 ? C ASP 354 
213 1 Y 1 C GLY 364 ? C GLY 355 
214 1 Y 1 C MET 365 ? C MET 356 
215 1 Y 1 C THR 366 ? C THR 357 
216 1 Y 1 C PRO 367 ? C PRO 358 
217 1 Y 1 C LYS 368 ? C LYS 359 
218 1 Y 1 C GLY 369 ? C GLY 360 
219 1 Y 1 C PRO 370 ? C PRO 361 
220 1 Y 1 C ASN 371 ? C ASN 362 
221 1 Y 1 C HIS 372 ? C HIS 363 
222 1 Y 1 C PRO 373 ? C PRO 364 
223 1 Y 1 C VAL 374 ? C VAL 365 
224 1 Y 1 C GLN 375 ? C GLN 366 
225 1 Y 1 C VAL 376 ? C VAL 367 
226 1 Y 1 C MET 377 ? C MET 368 
227 1 Y 1 C PRO 378 ? C PRO 369 
228 1 Y 1 C LYS 379 ? C LYS 370 
229 1 Y 1 C SER 380 ? C SER 371 
230 1 Y 1 C PRO 381 ? C PRO 372 
231 1 Y 1 C ASP 382 ? C ASP 373 
232 1 Y 1 C GLU 383 ? C GLU 374 
233 1 Y 1 C MET 384 ? C MET 375 
234 1 Y 1 C ARG 385 ? C ARG 376 
235 1 Y 1 C HIS 423 ? C HIS 414 
236 1 Y 1 C GLU 424 ? C GLU 415 
237 1 Y 1 C ASP 425 ? C ASP 416 
238 1 Y 1 C ILE 426 ? C ILE 417 
239 1 Y 1 C HIS 427 ? C HIS 418 
240 1 Y 1 C GLN 428 ? C GLN 419 
241 1 Y 1 C GLN 429 ? C GLN 420 
242 1 Y 1 C GLN 430 ? C GLN 421 
243 1 Y 1 C ASP 431 ? C ASP 422 
244 1 Y 1 D ALA 1   ? D ALA 1   
245 1 Y 1 D ARG 2   ? D ARG 2   
246 1 Y 1 D SER 3   ? D SER 3   
247 1 Y 1 D ARG 4   ? D ARG 4   
248 1 Y 1 D SER 5   ? D SER 5   
249 1 Y 1 D ALA 6   ? D ALA 6   
250 1 Y 1 D PRO 7   ? D PRO 7   
251 1 Y 1 D HIS 320 ? D HIS 311 
252 1 Y 1 D LYS 321 ? D LYS 312 
253 1 Y 1 D GLU 322 ? D GLU 313 
254 1 Y 1 D LEU 323 ? D LEU 314 
255 1 Y 1 D LEU 324 ? D LEU 315 
256 1 Y 1 D ARG 325 ? D ARG 316 
257 1 Y 1 D PHE 326 ? D PHE 317 
258 1 Y 1 D ARG 327 ? D ARG 318 
259 1 Y 1 D ARG 328 ? D ARG 319 
260 1 Y 1 D LYS 329 ? D LYS 320 
261 1 Y 1 D ARG 330 ? D ARG 321 
262 1 Y 1 D LYS 331 ? D LYS 322 
263 1 Y 1 D ASN 332 ? D ASN 323 
264 1 Y 1 D LYS 333 ? D LYS 324 
265 1 Y 1 D THR 334 ? D THR 325 
266 1 Y 1 D GLU 335 ? D GLU 326 
267 1 Y 1 D ALA 336 ? D ALA 327 
268 1 Y 1 D PHE 337 ? D PHE 328 
269 1 Y 1 D ASP 338 ? D ASP 329 
270 1 Y 1 D MET 339 ? D MET 330 
271 1 Y 1 D ASP 340 ? D ASP 331 
272 1 Y 1 D ASP 341 ? D ASP 332 
273 1 Y 1 D GLU 342 ? D GLU 333 
274 1 Y 1 D VAL 343 ? D VAL 334 
275 1 Y 1 D ARG 344 ? D ARG 335 
276 1 Y 1 D GLU 345 ? D GLU 336 
277 1 Y 1 D GLU 346 ? D GLU 337 
278 1 Y 1 D ARG 347 ? D ARG 338 
279 1 Y 1 D PHE 348 ? D PHE 339 
280 1 Y 1 D SER 349 ? D SER 340 
281 1 Y 1 D PHE 350 ? D PHE 341 
282 1 Y 1 D THR 351 ? D THR 342 
283 1 Y 1 D ALA 352 ? D ALA 343 
284 1 Y 1 D TYR 353 ? D TYR 344 
285 1 Y 1 D GLY 354 ? D GLY 345 
286 1 Y 1 D MET 355 ? D MET 346 
287 1 Y 1 D GLY 356 ? D GLY 347 
288 1 Y 1 D PRO 357 ? D PRO 348 
289 1 Y 1 D CYS 358 ? D CYS 349 
290 1 Y 1 D LEU 359 ? D LEU 350 
291 1 Y 1 D GLN 360 ? D GLN 351 
292 1 Y 1 D ALA 361 ? D ALA 352 
293 1 Y 1 D LYS 362 ? D LYS 353 
294 1 Y 1 D ASP 363 ? D ASP 354 
295 1 Y 1 D GLY 364 ? D GLY 355 
296 1 Y 1 D MET 365 ? D MET 356 
297 1 Y 1 D THR 366 ? D THR 357 
298 1 Y 1 D PRO 367 ? D PRO 358 
299 1 Y 1 D LYS 368 ? D LYS 359 
300 1 Y 1 D GLY 369 ? D GLY 360 
301 1 Y 1 D PRO 370 ? D PRO 361 
302 1 Y 1 D ASN 371 ? D ASN 362 
303 1 Y 1 D HIS 372 ? D HIS 363 
304 1 Y 1 D PRO 373 ? D PRO 364 
305 1 Y 1 D VAL 374 ? D VAL 365 
306 1 Y 1 D GLN 375 ? D GLN 366 
307 1 Y 1 D VAL 376 ? D VAL 367 
308 1 Y 1 D MET 377 ? D MET 368 
309 1 Y 1 D PRO 378 ? D PRO 369 
310 1 Y 1 D LYS 379 ? D LYS 370 
311 1 Y 1 D SER 380 ? D SER 371 
312 1 Y 1 D PRO 381 ? D PRO 372 
313 1 Y 1 D ASP 382 ? D ASP 373 
314 1 Y 1 D GLU 383 ? D GLU 374 
315 1 Y 1 D MET 384 ? D MET 375 
316 1 Y 1 D ILE 426 ? D ILE 417 
317 1 Y 1 D HIS 427 ? D HIS 418 
318 1 Y 1 D GLN 428 ? D GLN 419 
319 1 Y 1 D GLN 429 ? D GLN 420 
320 1 Y 1 D GLN 430 ? D GLN 421 
321 1 Y 1 D ASP 431 ? D ASP 422 
322 1 Y 1 E LYS 3   ? E LYS 1   
323 1 Y 1 E SER 4   ? E SER 2   
324 1 Y 1 E SER 5   ? E SER 3   
325 1 Y 1 E LYS 6   ? E LYS 4   
326 1 Y 1 E LYS 7   ? E LYS 5   
327 1 Y 1 E GLY 8   ? E GLY 6   
328 1 Y 1 E LYS 9   ? E LYS 7   
329 1 Y 1 E GLY 10  ? E GLY 8   
330 1 Y 1 E LYS 11  ? E LYS 9   
331 1 Y 1 E LYS 12  ? E LYS 10  
332 1 Y 1 E LYS 13  ? E LYS 11  
333 1 Y 1 E GLN 14  ? E GLN 12  
334 1 Y 1 E TYR 15  ? E TYR 13  
335 1 Y 1 E LEU 16  ? E LEU 14  
336 1 Y 1 E CYS 17  ? E CYS 15  
337 1 Y 1 E PRO 18  ? E PRO 16  
338 1 Y 1 E SER 19  ? E SER 17  
339 1 Y 1 E GLN 20  ? E GLN 18  
340 1 Y 1 E GLN 21  ? E GLN 19  
341 1 Y 1 E SER 22  ? E SER 20  
342 1 Y 1 E ALA 23  ? E ALA 21  
343 1 Y 1 E GLU 24  ? E GLU 22  
344 1 Y 1 E ASP 25  ? E ASP 23  
345 1 Y 1 E LEU 26  ? E LEU 24  
346 1 Y 1 E ALA 27  ? E ALA 25  
347 1 Y 1 E ARG 28  ? E ARG 26  
348 1 Y 1 E GLY 333 A E GLY 332 
349 1 Y 1 E GLY 333 B E GLY 333 
350 1 Y 1 E SER 333 C E SER 334 
351 1 Y 1 E SER 333 D E SER 335 
352 1 Y 1 E ALA 333 E E ALA 336 
353 1 Y 1 E ALA 333 F E ALA 337 
354 1 Y 1 E ALA 333 G E ALA 338 
355 1 Y 1 E VAL 333 H E VAL 339 
356 1 Y 1 E SER 333 I E SER 340 
357 1 Y 1 E LYS 333 J E LYS 341 
358 1 Y 1 E GLY 333 K E GLY 342 
359 1 Y 1 E GLU 333 L E GLU 343 
360 1 Y 1 E GLU 333 M E GLU 344 
361 1 Y 1 E LEU 333 N E LEU 345 
362 1 Y 1 E PHE 333 O E PHE 346 
363 1 Y 1 E THR 333 P E THR 347 
364 1 Y 1 E GLY 333 Q E GLY 348 
365 1 Y 1 E VAL 333 R E VAL 349 
366 1 Y 1 E VAL 333 S E VAL 350 
367 1 Y 1 E PRO 333 T E PRO 351 
368 1 Y 1 E ILE 333 U E ILE 352 
369 1 Y 1 E LEU 333 V E LEU 353 
370 1 Y 1 E VAL 333 W E VAL 354 
371 1 Y 1 E GLU 333 X E GLU 355 
372 1 Y 1 E LEU 333 Y E LEU 356 
373 1 Y 1 E ASP 333 Z E ASP 357 
374 1 Y 1 E GLY 334 A E GLY 358 
375 1 Y 1 E ASP 334 B E ASP 359 
376 1 Y 1 E VAL 334 C E VAL 360 
377 1 Y 1 E ASN 334 D E ASN 361 
378 1 Y 1 E GLY 334 E E GLY 362 
379 1 Y 1 E HIS 334 F E HIS 363 
380 1 Y 1 E LYS 334 G E LYS 364 
381 1 Y 1 E PHE 334 H E PHE 365 
382 1 Y 1 E SER 334 I E SER 366 
383 1 Y 1 E VAL 334 J E VAL 367 
384 1 Y 1 E SER 334 K E SER 368 
385 1 Y 1 E GLY 334 L E GLY 369 
386 1 Y 1 E GLU 334 M E GLU 370 
387 1 Y 1 E GLY 334 N E GLY 371 
388 1 Y 1 E GLU 334 O E GLU 372 
389 1 Y 1 E GLY 334 P E GLY 373 
390 1 Y 1 E ASP 334 Q E ASP 374 
391 1 Y 1 E ALA 334 R E ALA 375 
392 1 Y 1 E THR 334 S E THR 376 
393 1 Y 1 E TYR 334 T E TYR 377 
394 1 Y 1 E GLY 334 U E GLY 378 
395 1 Y 1 E LYS 334 V E LYS 379 
396 1 Y 1 E LEU 334 W E LEU 380 
397 1 Y 1 E THR 334 X E THR 381 
398 1 Y 1 E LEU 334 Y E LEU 382 
399 1 Y 1 E LYS 334 Z E LYS 383 
400 1 Y 1 E PHE 335 A E PHE 384 
401 1 Y 1 E ILE 335 B E ILE 385 
402 1 Y 1 E CYS 335 C E CYS 386 
403 1 Y 1 E THR 335 D E THR 387 
404 1 Y 1 E THR 335 E E THR 388 
405 1 Y 1 E GLY 335 F E GLY 389 
406 1 Y 1 E LYS 335 G E LYS 390 
407 1 Y 1 E LEU 335 H E LEU 391 
408 1 Y 1 E PRO 335 I E PRO 392 
409 1 Y 1 E VAL 335 J E VAL 393 
410 1 Y 1 E PRO 335 K E PRO 394 
411 1 Y 1 E TRP 335 L E TRP 395 
412 1 Y 1 E PRO 335 M E PRO 396 
413 1 Y 1 E THR 335 N E THR 397 
414 1 Y 1 E LEU 335 O E LEU 398 
415 1 Y 1 E VAL 335 P E VAL 399 
416 1 Y 1 E THR 335 Q E THR 400 
417 1 Y 1 E THR 335 R E THR 401 
418 1 Y 1 E PHE 335 S E PHE 402 
419 1 Y 1 E SER 335 T E SER 403 
420 1 Y 1 E TYR 335 U E TYR 404 
421 1 Y 1 E GLY 335 V E GLY 405 
422 1 Y 1 E VAL 335 W E VAL 406 
423 1 Y 1 E GLN 335 X E GLN 407 
424 1 Y 1 E CYS 335 Y E CYS 408 
425 1 Y 1 E PHE 335 Z E PHE 409 
426 1 Y 1 E SER 336 A E SER 410 
427 1 Y 1 E ARG 336 B E ARG 411 
428 1 Y 1 E TYR 336 C E TYR 412 
429 1 Y 1 E PRO 336 D E PRO 413 
430 1 Y 1 E ASP 336 E E ASP 414 
431 1 Y 1 E HIS 336 F E HIS 415 
432 1 Y 1 E MET 336 G E MET 416 
433 1 Y 1 E LYS 336 H E LYS 417 
434 1 Y 1 E GLN 336 I E GLN 418 
435 1 Y 1 E HIS 336 J E HIS 419 
436 1 Y 1 E ASP 336 K E ASP 420 
437 1 Y 1 E PHE 336 L E PHE 421 
438 1 Y 1 E PHE 336 M E PHE 422 
439 1 Y 1 E LYS 336 N E LYS 423 
440 1 Y 1 E SER 336 O E SER 424 
441 1 Y 1 E ALA 336 P E ALA 425 
442 1 Y 1 E MET 336 Q E MET 426 
443 1 Y 1 E PRO 336 R E PRO 427 
444 1 Y 1 E GLU 336 S E GLU 428 
445 1 Y 1 E GLY 336 T E GLY 429 
446 1 Y 1 E TYR 336 U E TYR 430 
447 1 Y 1 E VAL 336 V E VAL 431 
448 1 Y 1 E GLN 336 W E GLN 432 
449 1 Y 1 E GLU 336 X E GLU 433 
450 1 Y 1 E ARG 336 Y E ARG 434 
451 1 Y 1 E THR 336 Z E THR 435 
452 1 Y 1 E ILE 337 A E ILE 436 
453 1 Y 1 E PHE 337 B E PHE 437 
454 1 Y 1 E PHE 337 C E PHE 438 
455 1 Y 1 E LYS 337 D E LYS 439 
456 1 Y 1 E ASP 337 E E ASP 440 
457 1 Y 1 E ASP 337 F E ASP 441 
458 1 Y 1 E GLY 337 G E GLY 442 
459 1 Y 1 E ASN 337 H E ASN 443 
460 1 Y 1 E TYR 337 I E TYR 444 
461 1 Y 1 E LYS 337 J E LYS 445 
462 1 Y 1 E THR 337 K E THR 446 
463 1 Y 1 E ARG 337 L E ARG 447 
464 1 Y 1 E ALA 337 M E ALA 448 
465 1 Y 1 E GLU 337 N E GLU 449 
466 1 Y 1 E VAL 337 O E VAL 450 
467 1 Y 1 E LYS 337 P E LYS 451 
468 1 Y 1 E PHE 337 Q E PHE 452 
469 1 Y 1 E GLU 337 R E GLU 453 
470 1 Y 1 E GLY 337 S E GLY 454 
471 1 Y 1 E ASP 337 T E ASP 455 
472 1 Y 1 E THR 337 U E THR 456 
473 1 Y 1 E LEU 337 V E LEU 457 
474 1 Y 1 E VAL 337 W E VAL 458 
475 1 Y 1 E ASN 337 X E ASN 459 
476 1 Y 1 E ARG 337 Y E ARG 460 
477 1 Y 1 E ILE 337 Z E ILE 461 
478 1 Y 1 E GLU 338 A E GLU 462 
479 1 Y 1 E LEU 338 B E LEU 463 
480 1 Y 1 E LYS 338 C E LYS 464 
481 1 Y 1 E GLY 338 D E GLY 465 
482 1 Y 1 E ILE 338 E E ILE 466 
483 1 Y 1 E ASP 338 F E ASP 467 
484 1 Y 1 E PHE 338 G E PHE 468 
485 1 Y 1 E LYS 338 H E LYS 469 
486 1 Y 1 E GLU 338 I E GLU 470 
487 1 Y 1 E ASP 338 J E ASP 471 
488 1 Y 1 E GLY 338 K E GLY 472 
489 1 Y 1 E ASN 338 L E ASN 473 
490 1 Y 1 E ILE 338 M E ILE 474 
491 1 Y 1 E LEU 338 N E LEU 475 
492 1 Y 1 E GLY 338 O E GLY 476 
493 1 Y 1 E HIS 338 P E HIS 477 
494 1 Y 1 E LYS 338 Q E LYS 478 
495 1 Y 1 E LEU 338 R E LEU 479 
496 1 Y 1 E GLU 338 S E GLU 480 
497 1 Y 1 E TYR 338 T E TYR 481 
498 1 Y 1 E ASN 338 U E ASN 482 
499 1 Y 1 E TYR 338 V E TYR 483 
500 1 Y 1 E ASN 338 W E ASN 484 
501 1 Y 1 E SER 338 X E SER 485 
502 1 Y 1 E HIS 338 Y E HIS 486 
503 1 Y 1 E ASN 338 Z E ASN 487 
504 1 Y 1 E VAL 339 A E VAL 488 
505 1 Y 1 E TYR 339 B E TYR 489 
506 1 Y 1 E ILE 339 C E ILE 490 
507 1 Y 1 E MET 339 D E MET 491 
508 1 Y 1 E ALA 339 E E ALA 492 
509 1 Y 1 E ASP 339 F E ASP 493 
510 1 Y 1 E LYS 339 G E LYS 494 
511 1 Y 1 E GLN 339 H E GLN 495 
512 1 Y 1 E LYS 339 I E LYS 496 
513 1 Y 1 E ASN 339 J E ASN 497 
514 1 Y 1 E GLY 339 K E GLY 498 
515 1 Y 1 E ILE 339 L E ILE 499 
516 1 Y 1 E LYS 339 M E LYS 500 
517 1 Y 1 E VAL 339 N E VAL 501 
518 1 Y 1 E ASN 339 O E ASN 502 
519 1 Y 1 E PHE 339 P E PHE 503 
520 1 Y 1 E LYS 339 Q E LYS 504 
521 1 Y 1 E ILE 339 R E ILE 505 
522 1 Y 1 E ARG 339 S E ARG 506 
523 1 Y 1 E HIS 339 T E HIS 507 
524 1 Y 1 E ASN 339 U E ASN 508 
525 1 Y 1 E ILE 339 V E ILE 509 
526 1 Y 1 E GLU 339 W E GLU 510 
527 1 Y 1 E ASP 339 X E ASP 511 
528 1 Y 1 E GLY 339 Y E GLY 512 
529 1 Y 1 E SER 339 Z E SER 513 
530 1 Y 1 E VAL 340 A E VAL 514 
531 1 Y 1 E GLN 340 B E GLN 515 
532 1 Y 1 E LEU 340 C E LEU 516 
533 1 Y 1 E ALA 340 D E ALA 517 
534 1 Y 1 E ASP 340 E E ASP 518 
535 1 Y 1 E HIS 340 F E HIS 519 
536 1 Y 1 E TYR 340 G E TYR 520 
537 1 Y 1 E GLN 340 H E GLN 521 
538 1 Y 1 E GLN 340 I E GLN 522 
539 1 Y 1 E ASN 340 J E ASN 523 
540 1 Y 1 E THR 340 K E THR 524 
541 1 Y 1 E PRO 340 L E PRO 525 
542 1 Y 1 E ILE 340 M E ILE 526 
543 1 Y 1 E GLY 340 N E GLY 527 
544 1 Y 1 E ASP 340 O E ASP 528 
545 1 Y 1 E GLY 340 P E GLY 529 
546 1 Y 1 E PRO 340 Q E PRO 530 
547 1 Y 1 E VAL 340 R E VAL 531 
548 1 Y 1 E LEU 340 S E LEU 532 
549 1 Y 1 E LEU 340 T E LEU 533 
550 1 Y 1 E PRO 340 U E PRO 534 
551 1 Y 1 E ASP 340 V E ASP 535 
552 1 Y 1 E ASN 340 W E ASN 536 
553 1 Y 1 E HIS 340 X E HIS 537 
554 1 Y 1 E TYR 340 Y E TYR 538 
555 1 Y 1 E LEU 340 Z E LEU 539 
556 1 Y 1 E SER 341 A E SER 540 
557 1 Y 1 E THR 341 B E THR 541 
558 1 Y 1 E GLN 341 C E GLN 542 
559 1 Y 1 E SER 341 D E SER 543 
560 1 Y 1 E ALA 341 E E ALA 544 
561 1 Y 1 E LEU 341 F E LEU 545 
562 1 Y 1 E SER 341 G E SER 546 
563 1 Y 1 E LYS 341 H E LYS 547 
564 1 Y 1 E ASP 341 I E ASP 548 
565 1 Y 1 E PRO 341 J E PRO 549 
566 1 Y 1 E ASN 341 K E ASN 550 
567 1 Y 1 E GLU 341 L E GLU 551 
568 1 Y 1 E LYS 341 M E LYS 552 
569 1 Y 1 E ARG 341 N E ARG 553 
570 1 Y 1 E ASP 341 O E ASP 554 
571 1 Y 1 E HIS 341 P E HIS 555 
572 1 Y 1 E MET 341 Q E MET 556 
573 1 Y 1 E VAL 341 R E VAL 557 
574 1 Y 1 E LEU 341 S E LEU 558 
575 1 Y 1 E LEU 341 T E LEU 559 
576 1 Y 1 E GLU 341 U E GLU 560 
577 1 Y 1 E PHE 341 V E PHE 561 
578 1 Y 1 E VAL 341 W E VAL 562 
579 1 Y 1 E THR 341 X E THR 563 
580 1 Y 1 E ALA 341 Y E ALA 564 
581 1 Y 1 E ALA 341 Z E ALA 565 
582 1 Y 1 E GLY 342 A E GLY 566 
583 1 Y 1 E ILE 342 B E ILE 567 
584 1 Y 1 E THR 342 C E THR 568 
585 1 Y 1 E HIS 342 D E HIS 569 
586 1 Y 1 E GLY 342 E E GLY 570 
587 1 Y 1 E MET 342 F E MET 571 
588 1 Y 1 E ASP 342 G E ASP 572 
589 1 Y 1 E GLU 342 H E GLU 573 
590 1 Y 1 E LEU 342 I E LEU 574 
591 1 Y 1 E TYR 342 J E TYR 575 
592 1 Y 1 E LYS 342 K E LYS 576 
593 1 Y 1 E SER 342 L E SER 577 
594 1 Y 1 E GLY 342 M E GLY 578 
595 1 Y 1 E SER 342 N E SER 579 
596 1 Y 1 E GLY 342 O E GLY 580 
597 1 Y 1 E SER 342 P E SER 581 
598 1 Y 1 E GLY 342 Q E GLY 582 
599 1 Y 1 E VAL 342 R E VAL 583 
600 1 Y 1 E GLY 342 S E GLY 584 
601 1 Y 1 E GLU 342 T E GLU 585 
602 1 Y 1 E THR 342 U E THR 586 
603 1 Y 1 E ARG 342 V E ARG 587 
604 1 Y 1 E CYS 342 W E CYS 588 
605 1 Y 1 E LYS 342 X E LYS 589 
606 1 Y 1 E LYS 342 Y E LYS 590 
607 1 Y 1 E VAL 342 Z E VAL 591 
608 1 Y 1 E CYS 343 A E CYS 592 
609 1 Y 1 E THR 343 B E THR 593 
610 1 Y 1 E SER 343 C E SER 594 
611 1 Y 1 E LYS 343 D E LYS 595 
612 1 Y 1 E SER 343 E E SER 596 
613 1 Y 1 E ASP 343 F E ASP 597 
614 1 Y 1 E LEU 343 G E LEU 598 
615 1 Y 1 E ARG 343 H E ARG 599 
616 1 Y 1 E SER 343 I E SER 600 
617 1 Y 1 E ASN 343 J E ASN 601 
618 1 Y 1 E ASP 343 K E ASP 602 
619 1 Y 1 E PHE 343 L E PHE 603 
620 1 Y 1 E SER 343 M E SER 604 
621 1 Y 1 E ILE 343 N E ILE 605 
622 1 Y 1 E VAL 343 O E VAL 606 
623 1 Y 1 E GLY 343 P E GLY 607 
624 1 Y 1 E SER 343 Q E SER 608 
625 1 Y 1 E LEU 343 R E LEU 609 
626 1 Y 1 E PRO 343 S E PRO 610 
627 1 Y 1 E ARG 343 T E ARG 611 
628 1 Y 1 E ASP 343 U E ASP 612 
629 1 Y 1 E PHE 343 V E PHE 613 
630 1 Y 1 E GLU 343 W E GLU 614 
631 1 Y 1 E LEU 343 X E LEU 615 
632 1 Y 1 E SER 343 Y E SER 616 
633 1 Y 1 E ASN 343 Z E ASN 617 
634 1 Y 1 E TYR 344 A E TYR 618 
635 1 Y 1 E ASP 344 B E ASP 619 
636 1 Y 1 E CYS 344 C E CYS 620 
637 1 Y 1 E TYR 344 D E TYR 621 
638 1 Y 1 E GLY 344 E E GLY 622 
639 1 Y 1 E LYS 344 F E LYS 623 
640 1 Y 1 E PRO 344 G E PRO 624 
641 1 Y 1 E ILE 344 H E ILE 625 
642 1 Y 1 E GLU 344 I E GLU 626 
643 1 Y 1 E VAL 344 J E VAL 627 
644 1 Y 1 E ASN 344 K E ASN 628 
645 1 Y 1 E ASN 344 L E ASN 629 
646 1 Y 1 E GLY 344 M E GLY 630 
647 1 Y 1 E LEU 344 N E LEU 631 
648 1 Y 1 E GLY 344 O E GLY 632 
649 1 Y 1 E LYS 344 P E LYS 633 
650 1 Y 1 E SER 344 Q E SER 634 
651 1 Y 1 E GLN 344 R E GLN 635 
652 1 Y 1 E ALA 344 S E ALA 636 
653 1 Y 1 E LYS 344 T E LYS 637 
654 1 Y 1 E ASN 344 U E ASN 638 
655 1 Y 1 E ASN 344 V E ASN 639 
656 1 Y 1 E LYS 344 W E LYS 640 
657 1 Y 1 E LYS 344 X E LYS 641 
658 1 Y 1 E PRO 344 Y E PRO 642 
659 1 Y 1 E PRO 344 Z E PRO 643 
660 1 Y 1 E PRO 345 A E PRO 644 
661 1 Y 1 E ALA 345 B E ALA 645 
662 1 Y 1 E LYS 345 C E LYS 646 
663 1 Y 1 E PRO 345 D E PRO 647 
664 1 Y 1 E VAL 345 E E VAL 648 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAG C1   C N R 247 
NAG C2   C N R 248 
NAG C3   C N R 249 
NAG C4   C N S 250 
NAG C5   C N R 251 
NAG C6   C N N 252 
NAG C7   C N N 253 
NAG C8   C N N 254 
NAG N2   N N N 255 
NAG O1   O N N 256 
NAG O3   O N N 257 
NAG O4   O N N 258 
NAG O5   O N N 259 
NAG O6   O N N 260 
NAG O7   O N N 261 
NAG H1   H N N 262 
NAG H2   H N N 263 
NAG H3   H N N 264 
NAG H4   H N N 265 
NAG H5   H N N 266 
NAG H61  H N N 267 
NAG H62  H N N 268 
NAG H81  H N N 269 
NAG H82  H N N 270 
NAG H83  H N N 271 
NAG HN2  H N N 272 
NAG HO1  H N N 273 
NAG HO3  H N N 274 
NAG HO4  H N N 275 
NAG HO6  H N N 276 
PHE N    N N N 277 
PHE CA   C N S 278 
PHE C    C N N 279 
PHE O    O N N 280 
PHE CB   C N N 281 
PHE CG   C Y N 282 
PHE CD1  C Y N 283 
PHE CD2  C Y N 284 
PHE CE1  C Y N 285 
PHE CE2  C Y N 286 
PHE CZ   C Y N 287 
PHE OXT  O N N 288 
PHE H    H N N 289 
PHE H2   H N N 290 
PHE HA   H N N 291 
PHE HB2  H N N 292 
PHE HB3  H N N 293 
PHE HD1  H N N 294 
PHE HD2  H N N 295 
PHE HE1  H N N 296 
PHE HE2  H N N 297 
PHE HZ   H N N 298 
PHE HXT  H N N 299 
PRO N    N N N 300 
PRO CA   C N S 301 
PRO C    C N N 302 
PRO O    O N N 303 
PRO CB   C N N 304 
PRO CG   C N N 305 
PRO CD   C N N 306 
PRO OXT  O N N 307 
PRO H    H N N 308 
PRO HA   H N N 309 
PRO HB2  H N N 310 
PRO HB3  H N N 311 
PRO HG2  H N N 312 
PRO HG3  H N N 313 
PRO HD2  H N N 314 
PRO HD3  H N N 315 
PRO HXT  H N N 316 
SER N    N N N 317 
SER CA   C N S 318 
SER C    C N N 319 
SER O    O N N 320 
SER CB   C N N 321 
SER OG   O N N 322 
SER OXT  O N N 323 
SER H    H N N 324 
SER H2   H N N 325 
SER HA   H N N 326 
SER HB2  H N N 327 
SER HB3  H N N 328 
SER HG   H N N 329 
SER HXT  H N N 330 
THR N    N N N 331 
THR CA   C N S 332 
THR C    C N N 333 
THR O    O N N 334 
THR CB   C N R 335 
THR OG1  O N N 336 
THR CG2  C N N 337 
THR OXT  O N N 338 
THR H    H N N 339 
THR H2   H N N 340 
THR HA   H N N 341 
THR HB   H N N 342 
THR HG1  H N N 343 
THR HG21 H N N 344 
THR HG22 H N N 345 
THR HG23 H N N 346 
THR HXT  H N N 347 
TRP N    N N N 348 
TRP CA   C N S 349 
TRP C    C N N 350 
TRP O    O N N 351 
TRP CB   C N N 352 
TRP CG   C Y N 353 
TRP CD1  C Y N 354 
TRP CD2  C Y N 355 
TRP NE1  N Y N 356 
TRP CE2  C Y N 357 
TRP CE3  C Y N 358 
TRP CZ2  C Y N 359 
TRP CZ3  C Y N 360 
TRP CH2  C Y N 361 
TRP OXT  O N N 362 
TRP H    H N N 363 
TRP H2   H N N 364 
TRP HA   H N N 365 
TRP HB2  H N N 366 
TRP HB3  H N N 367 
TRP HD1  H N N 368 
TRP HE1  H N N 369 
TRP HE3  H N N 370 
TRP HZ2  H N N 371 
TRP HZ3  H N N 372 
TRP HH2  H N N 373 
TRP HXT  H N N 374 
TYR N    N N N 375 
TYR CA   C N S 376 
TYR C    C N N 377 
TYR O    O N N 378 
TYR CB   C N N 379 
TYR CG   C Y N 380 
TYR CD1  C Y N 381 
TYR CD2  C Y N 382 
TYR CE1  C Y N 383 
TYR CE2  C Y N 384 
TYR CZ   C Y N 385 
TYR OH   O N N 386 
TYR OXT  O N N 387 
TYR H    H N N 388 
TYR H2   H N N 389 
TYR HA   H N N 390 
TYR HB2  H N N 391 
TYR HB3  H N N 392 
TYR HD1  H N N 393 
TYR HD2  H N N 394 
TYR HE1  H N N 395 
TYR HE2  H N N 396 
TYR HH   H N N 397 
TYR HXT  H N N 398 
VAL N    N N N 399 
VAL CA   C N S 400 
VAL C    C N N 401 
VAL O    O N N 402 
VAL CB   C N N 403 
VAL CG1  C N N 404 
VAL CG2  C N N 405 
VAL OXT  O N N 406 
VAL H    H N N 407 
VAL H2   H N N 408 
VAL HA   H N N 409 
VAL HB   H N N 410 
VAL HG11 H N N 411 
VAL HG12 H N N 412 
VAL HG13 H N N 413 
VAL HG21 H N N 414 
VAL HG22 H N N 415 
VAL HG23 H N N 416 
VAL HXT  H N N 417 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
SER N   CA   sing N N 305 
SER N   H    sing N N 306 
SER N   H2   sing N N 307 
SER CA  C    sing N N 308 
SER CA  CB   sing N N 309 
SER CA  HA   sing N N 310 
SER C   O    doub N N 311 
SER C   OXT  sing N N 312 
SER CB  OG   sing N N 313 
SER CB  HB2  sing N N 314 
SER CB  HB3  sing N N 315 
SER OG  HG   sing N N 316 
SER OXT HXT  sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-05-06 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9BP0 
_em_admin.last_update        2025-05-14 
_em_admin.map_release_date   2025-05-14 
_em_admin.title              'Cryo-EM structure  of human  heteromeric Glycine Receptor alpha3S346E-beta with glycine' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 200  mM       NaCl      1 'sodium chloride' 
1 20   mM       Tris-HCl  2 Tris-HCl          
1 0.06 '%(w/v)' digitonin 3 digitonin         
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.26 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 1 2 9606 'Homo sapiens' ? ? ? ? ? 
? ? 1 3 9606 'Homo sapiens' ? ? ? ? ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         69.6 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.21_5207: 
'IMAGE ACQUISITION'             ? 2  1 1 1 ?      ?          
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?          
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?          
CLASSIFICATION                  ? 5  1 1 1 ?      ?          
MASKING                         ? 6  1 1 1 ?      ?          
RECONSTRUCTION                  ? 7  1 1 1 ?      ?          
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?          
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?          
'CTF CORRECTION'                ? 10 1 1 1 ?      ?          
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?          
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?          
'MODEL FITTING'                 ? 13 1 1 1 ?      ?          
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?          
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?          
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?          
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?          
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?          
OTHER                           ? 19 1 1 1 ?      ?          
# 
_em_specimen.concentration           6 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Institutes of Health/National Cancer Institute (NIH/NCI)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           1R35GM146860 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   8DN4 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.crystal_system   triclinic 
_space_group.name_H-M_alt     'P 1' 
_space_group.IT_number        1 
_space_group.name_Hall        'P 1' 
_space_group.id               1 
# 
_atom_sites.entry_id                    9BP0 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . MET A 1 8   ? 129.213 151.070 181.251 1.00 85.42  ? 8   MET A N   1 
ATOM   2     C CA  . MET A 1 8   ? 130.348 151.255 180.354 1.00 85.42  ? 8   MET A CA  1 
ATOM   3     C C   . MET A 1 8   ? 130.775 149.931 179.730 1.00 85.42  ? 8   MET A C   1 
ATOM   4     O O   . MET A 1 8   ? 131.399 149.908 178.669 1.00 85.42  ? 8   MET A O   1 
ATOM   5     C CB  . MET A 1 8   ? 131.524 151.889 181.099 1.00 85.42  ? 8   MET A CB  1 
ATOM   6     C CG  . MET A 1 8   ? 131.211 153.243 181.711 1.00 85.42  ? 8   MET A CG  1 
ATOM   7     S SD  . MET A 1 8   ? 129.982 153.142 183.026 1.00 85.42  ? 8   MET A SD  1 
ATOM   8     C CE  . MET A 1 8   ? 131.029 152.836 184.447 1.00 85.42  ? 8   MET A CE  1 
ATOM   9     N N   . SER A 1 9   ? 130.438 148.833 180.395 1.00 76.10  ? 9   SER A N   1 
ATOM   10    C CA  . SER A 1 9   ? 130.780 147.515 179.877 1.00 76.10  ? 9   SER A CA  1 
ATOM   11    C C   . SER A 1 9   ? 129.995 147.248 178.598 1.00 76.10  ? 9   SER A C   1 
ATOM   12    O O   . SER A 1 9   ? 128.767 147.396 178.589 1.00 76.10  ? 9   SER A O   1 
ATOM   13    C CB  . SER A 1 9   ? 130.485 146.438 180.917 1.00 76.10  ? 9   SER A CB  1 
ATOM   14    O OG  . SER A 1 9   ? 130.858 145.157 180.442 1.00 76.10  ? 9   SER A OG  1 
ATOM   15    N N   . PRO A 1 10  ? 130.659 146.871 177.501 1.00 68.48  ? 10  PRO A N   1 
ATOM   16    C CA  . PRO A 1 10  ? 129.929 146.686 176.235 1.00 68.48  ? 10  PRO A CA  1 
ATOM   17    C C   . PRO A 1 10  ? 128.845 145.626 176.304 1.00 68.48  ? 10  PRO A C   1 
ATOM   18    O O   . PRO A 1 10  ? 127.779 145.796 175.698 1.00 68.48  ? 10  PRO A O   1 
ATOM   19    C CB  . PRO A 1 10  ? 131.041 146.304 175.250 1.00 68.48  ? 10  PRO A CB  1 
ATOM   20    C CG  . PRO A 1 10  ? 132.125 145.738 176.104 1.00 68.48  ? 10  PRO A CG  1 
ATOM   21    C CD  . PRO A 1 10  ? 132.082 146.516 177.381 1.00 68.48  ? 10  PRO A CD  1 
ATOM   22    N N   . SER A 1 11  ? 129.083 144.533 177.032 1.00 65.80  ? 11  SER A N   1 
ATOM   23    C CA  . SER A 1 11  ? 128.053 143.510 177.176 1.00 65.80  ? 11  SER A CA  1 
ATOM   24    C C   . SER A 1 11  ? 126.845 144.053 177.927 1.00 65.80  ? 11  SER A C   1 
ATOM   25    O O   . SER A 1 11  ? 125.697 143.815 177.532 1.00 65.80  ? 11  SER A O   1 
ATOM   26    C CB  . SER A 1 11  ? 128.624 142.287 177.891 1.00 65.80  ? 11  SER A CB  1 
ATOM   27    O OG  . SER A 1 11  ? 127.632 141.291 178.065 1.00 65.80  ? 11  SER A OG  1 
ATOM   28    N N   . ASP A 1 12  ? 127.085 144.797 179.008 1.00 64.72  ? 12  ASP A N   1 
ATOM   29    C CA  . ASP A 1 12  ? 125.982 145.391 179.753 1.00 64.72  ? 12  ASP A CA  1 
ATOM   30    C C   . ASP A 1 12  ? 125.240 146.416 178.907 1.00 64.72  ? 12  ASP A C   1 
ATOM   31    O O   . ASP A 1 12  ? 124.009 146.510 178.971 1.00 64.72  ? 12  ASP A O   1 
ATOM   32    C CB  . ASP A 1 12  ? 126.502 146.030 181.040 1.00 64.72  ? 12  ASP A CB  1 
ATOM   33    C CG  . ASP A 1 12  ? 125.610 145.744 182.230 1.00 64.72  ? 12  ASP A CG  1 
ATOM   34    O OD1 . ASP A 1 12  ? 124.695 144.904 182.100 1.00 64.72  ? 12  ASP A OD1 1 
ATOM   35    O OD2 . ASP A 1 12  ? 125.822 146.359 183.296 1.00 64.72  ? 12  ASP A OD2 1 
ATOM   36    N N   . PHE A 1 13  ? 125.972 147.197 178.110 1.00 63.08  ? 13  PHE A N   1 
ATOM   37    C CA  . PHE A 1 13  ? 125.323 148.166 177.235 1.00 63.08  ? 13  PHE A CA  1 
ATOM   38    C C   . PHE A 1 13  ? 124.441 147.475 176.203 1.00 63.08  ? 13  PHE A C   1 
ATOM   39    O O   . PHE A 1 13  ? 123.316 147.916 175.943 1.00 63.08  ? 13  PHE A O   1 
ATOM   40    C CB  . PHE A 1 13  ? 126.372 149.040 176.549 1.00 63.08  ? 13  PHE A CB  1 
ATOM   41    C CG  . PHE A 1 13  ? 125.863 149.760 175.336 1.00 63.08  ? 13  PHE A CG  1 
ATOM   42    C CD1 . PHE A 1 13  ? 125.233 150.984 175.459 1.00 63.08  ? 13  PHE A CD1 1 
ATOM   43    C CD2 . PHE A 1 13  ? 126.027 149.220 174.072 1.00 63.08  ? 13  PHE A CD2 1 
ATOM   44    C CE1 . PHE A 1 13  ? 124.765 151.650 174.348 1.00 63.08  ? 13  PHE A CE1 1 
ATOM   45    C CE2 . PHE A 1 13  ? 125.560 149.880 172.959 1.00 63.08  ? 13  PHE A CE2 1 
ATOM   46    C CZ  . PHE A 1 13  ? 124.930 151.098 173.096 1.00 63.08  ? 13  PHE A CZ  1 
ATOM   47    N N   . LEU A 1 14  ? 124.937 146.393 175.598 1.00 57.78  ? 14  LEU A N   1 
ATOM   48    C CA  . LEU A 1 14  ? 124.123 145.655 174.638 1.00 57.78  ? 14  LEU A CA  1 
ATOM   49    C C   . LEU A 1 14  ? 122.895 145.055 175.307 1.00 57.78  ? 14  LEU A C   1 
ATOM   50    O O   . LEU A 1 14  ? 121.805 145.040 174.723 1.00 57.78  ? 14  LEU A O   1 
ATOM   51    C CB  . LEU A 1 14  ? 124.951 144.563 173.963 1.00 57.78  ? 14  LEU A CB  1 
ATOM   52    C CG  . LEU A 1 14  ? 125.698 144.981 172.698 1.00 57.78  ? 14  LEU A CG  1 
ATOM   53    C CD1 . LEU A 1 14  ? 126.219 143.763 171.962 1.00 57.78  ? 14  LEU A CD1 1 
ATOM   54    C CD2 . LEU A 1 14  ? 124.793 145.801 171.799 1.00 57.78  ? 14  LEU A CD2 1 
ATOM   55    N N   . ASP A 1 15  ? 123.051 144.548 176.531 1.00 59.95  ? 15  ASP A N   1 
ATOM   56    C CA  . ASP A 1 15  ? 121.903 144.013 177.253 1.00 59.95  ? 15  ASP A CA  1 
ATOM   57    C C   . ASP A 1 15  ? 120.869 145.099 177.525 1.00 59.95  ? 15  ASP A C   1 
ATOM   58    O O   . ASP A 1 15  ? 119.664 144.869 177.379 1.00 59.95  ? 15  ASP A O   1 
ATOM   59    C CB  . ASP A 1 15  ? 122.359 143.365 178.559 1.00 59.95  ? 15  ASP A CB  1 
ATOM   60    C CG  . ASP A 1 15  ? 122.918 141.973 178.353 1.00 59.95  ? 15  ASP A CG  1 
ATOM   61    O OD1 . ASP A 1 15  ? 122.966 141.519 177.191 1.00 59.95  ? 15  ASP A OD1 1 
ATOM   62    O OD2 . ASP A 1 15  ? 123.306 141.334 179.352 1.00 59.95  ? 15  ASP A OD2 1 
ATOM   63    N N   . LYS A 1 16  ? 121.321 146.289 177.921 1.00 56.85  ? 16  LYS A N   1 
ATOM   64    C CA  . LYS A 1 16  ? 120.403 147.378 178.230 1.00 56.85  ? 16  LYS A CA  1 
ATOM   65    C C   . LYS A 1 16  ? 119.813 148.028 176.987 1.00 56.85  ? 16  LYS A C   1 
ATOM   66    O O   . LYS A 1 16  ? 118.801 148.727 177.093 1.00 56.85  ? 16  LYS A O   1 
ATOM   67    C CB  . LYS A 1 16  ? 121.110 148.440 179.073 1.00 56.85  ? 16  LYS A CB  1 
ATOM   68    C CG  . LYS A 1 16  ? 121.426 147.997 180.491 1.00 56.85  ? 16  LYS A CG  1 
ATOM   69    C CD  . LYS A 1 16  ? 122.304 149.012 181.204 1.00 56.85  ? 16  LYS A CD  1 
ATOM   70    C CE  . LYS A 1 16  ? 121.712 150.409 181.123 1.00 56.85  ? 16  LYS A CE  1 
ATOM   71    N NZ  . LYS A 1 16  ? 120.341 150.467 181.699 1.00 56.85  ? 16  LYS A NZ  1 
ATOM   72    N N   . LEU A 1 17  ? 120.421 147.824 175.818 1.00 57.81  ? 17  LEU A N   1 
ATOM   73    C CA  . LEU A 1 17  ? 119.898 148.424 174.595 1.00 57.81  ? 17  LEU A CA  1 
ATOM   74    C C   . LEU A 1 17  ? 118.742 147.610 174.028 1.00 57.81  ? 17  LEU A C   1 
ATOM   75    O O   . LEU A 1 17  ? 117.620 148.109 173.898 1.00 57.81  ? 17  LEU A O   1 
ATOM   76    C CB  . LEU A 1 17  ? 121.015 148.558 173.558 1.00 57.81  ? 17  LEU A CB  1 
ATOM   77    C CG  . LEU A 1 17  ? 120.708 149.451 172.358 1.00 57.81  ? 17  LEU A CG  1 
ATOM   78    C CD1 . LEU A 1 17  ? 120.210 150.803 172.825 1.00 57.81  ? 17  LEU A CD1 1 
ATOM   79    C CD2 . LEU A 1 17  ? 121.935 149.604 171.479 1.00 57.81  ? 17  LEU A CD2 1 
ATOM   80    N N   . MET A 1 18  ? 119.003 146.349 173.681 1.00 60.99  ? 18  MET A N   1 
ATOM   81    C CA  . MET A 1 18  ? 117.976 145.492 173.105 1.00 60.99  ? 18  MET A CA  1 
ATOM   82    C C   . MET A 1 18  ? 118.044 144.059 173.621 1.00 60.99  ? 18  MET A C   1 
ATOM   83    O O   . MET A 1 18  ? 117.377 143.182 173.057 1.00 60.99  ? 18  MET A O   1 
ATOM   84    C CB  . MET A 1 18  ? 118.067 145.517 171.573 1.00 60.99  ? 18  MET A CB  1 
ATOM   85    C CG  . MET A 1 18  ? 119.127 144.609 170.983 1.00 60.99  ? 18  MET A CG  1 
ATOM   86    S SD  . MET A 1 18  ? 120.773 145.292 171.220 1.00 60.99  ? 18  MET A SD  1 
ATOM   87    C CE  . MET A 1 18  ? 120.849 146.442 169.852 1.00 60.99  ? 18  MET A CE  1 
ATOM   88    N N   . GLY A 1 19  ? 118.799 143.797 174.683 1.00 68.43  ? 19  GLY A N   1 
ATOM   89    C CA  . GLY A 1 19  ? 118.900 142.469 175.243 1.00 68.43  ? 19  GLY A CA  1 
ATOM   90    C C   . GLY A 1 19  ? 117.683 142.103 176.072 1.00 68.43  ? 19  GLY A C   1 
ATOM   91    O O   . GLY A 1 19  ? 116.635 142.750 176.029 1.00 68.43  ? 19  GLY A O   1 
ATOM   92    N N   . ARG A 1 20  ? 117.838 141.024 176.844 1.00 71.05  ? 20  ARG A N   1 
ATOM   93    C CA  . ARG A 1 20  ? 116.731 140.532 177.658 1.00 71.05  ? 20  ARG A CA  1 
ATOM   94    C C   . ARG A 1 20  ? 116.309 141.554 178.706 1.00 71.05  ? 20  ARG A C   1 
ATOM   95    O O   . ARG A 1 20  ? 115.111 141.776 178.920 1.00 71.05  ? 20  ARG A O   1 
ATOM   96    C CB  . ARG A 1 20  ? 117.118 139.211 178.323 1.00 71.05  ? 20  ARG A CB  1 
ATOM   97    N N   . THR A 1 21  ? 117.275 142.191 179.368 1.00 62.31  ? 21  THR A N   1 
ATOM   98    C CA  . THR A 1 21  ? 116.960 143.148 180.420 1.00 62.31  ? 21  THR A CA  1 
ATOM   99    C C   . THR A 1 21  ? 116.583 144.521 179.885 1.00 62.31  ? 21  THR A C   1 
ATOM   100   O O   . THR A 1 21  ? 116.176 145.382 180.672 1.00 62.31  ? 21  THR A O   1 
ATOM   101   C CB  . THR A 1 21  ? 118.144 143.293 181.378 1.00 62.31  ? 21  THR A CB  1 
ATOM   102   O OG1 . THR A 1 21  ? 117.790 144.184 182.443 1.00 62.31  ? 21  THR A OG1 1 
ATOM   103   C CG2 . THR A 1 21  ? 119.350 143.852 180.646 1.00 62.31  ? 21  THR A CG2 1 
ATOM   104   N N   . SER A 1 22  ? 116.709 144.750 178.577 1.00 61.81  ? 22  SER A N   1 
ATOM   105   C CA  . SER A 1 22  ? 116.385 146.058 178.021 1.00 61.81  ? 22  SER A CA  1 
ATOM   106   C C   . SER A 1 22  ? 114.893 146.349 178.086 1.00 61.81  ? 22  SER A C   1 
ATOM   107   O O   . SER A 1 22  ? 114.495 147.507 178.253 1.00 61.81  ? 22  SER A O   1 
ATOM   108   C CB  . SER A 1 22  ? 116.867 146.147 176.575 1.00 61.81  ? 22  SER A CB  1 
ATOM   109   O OG  . SER A 1 22  ? 116.203 145.190 175.769 1.00 61.81  ? 22  SER A OG  1 
ATOM   110   N N   . GLY A 1 23  ? 114.059 145.323 177.956 1.00 62.59  ? 23  GLY A N   1 
ATOM   111   C CA  . GLY A 1 23  ? 112.632 145.514 177.842 1.00 62.59  ? 23  GLY A CA  1 
ATOM   112   C C   . GLY A 1 23  ? 112.144 145.768 176.435 1.00 62.59  ? 23  GLY A C   1 
ATOM   113   O O   . GLY A 1 23  ? 110.927 145.863 176.226 1.00 62.59  ? 23  GLY A O   1 
ATOM   114   N N   . TYR A 1 24  ? 113.048 145.886 175.466 1.00 51.51  ? 24  TYR A N   1 
ATOM   115   C CA  . TYR A 1 24  ? 112.646 146.063 174.080 1.00 51.51  ? 24  TYR A CA  1 
ATOM   116   C C   . TYR A 1 24  ? 111.962 144.805 173.565 1.00 51.51  ? 24  TYR A C   1 
ATOM   117   O O   . TYR A 1 24  ? 112.394 143.684 173.844 1.00 51.51  ? 24  TYR A O   1 
ATOM   118   C CB  . TYR A 1 24  ? 113.862 146.394 173.214 1.00 51.51  ? 24  TYR A CB  1 
ATOM   119   C CG  . TYR A 1 24  ? 113.544 146.572 171.749 1.00 51.51  ? 24  TYR A CG  1 
ATOM   120   C CD1 . TYR A 1 24  ? 112.944 147.733 171.288 1.00 51.51  ? 24  TYR A CD1 1 
ATOM   121   C CD2 . TYR A 1 24  ? 113.844 145.581 170.827 1.00 51.51  ? 24  TYR A CD2 1 
ATOM   122   C CE1 . TYR A 1 24  ? 112.651 147.903 169.951 1.00 51.51  ? 24  TYR A CE1 1 
ATOM   123   C CE2 . TYR A 1 24  ? 113.554 145.742 169.488 1.00 51.51  ? 24  TYR A CE2 1 
ATOM   124   C CZ  . TYR A 1 24  ? 112.958 146.906 169.056 1.00 51.51  ? 24  TYR A CZ  1 
ATOM   125   O OH  . TYR A 1 24  ? 112.665 147.078 167.724 1.00 51.51  ? 24  TYR A OH  1 
ATOM   126   N N   . ASP A 1 25  ? 110.884 144.995 172.811 1.00 52.59  ? 25  ASP A N   1 
ATOM   127   C CA  . ASP A 1 25  ? 110.114 143.898 172.242 1.00 52.59  ? 25  ASP A CA  1 
ATOM   128   C C   . ASP A 1 25  ? 110.263 143.930 170.728 1.00 52.59  ? 25  ASP A C   1 
ATOM   129   O O   . ASP A 1 25  ? 109.924 144.931 170.090 1.00 52.59  ? 25  ASP A O   1 
ATOM   130   C CB  . ASP A 1 25  ? 108.644 143.998 172.644 1.00 52.59  ? 25  ASP A CB  1 
ATOM   131   C CG  . ASP A 1 25  ? 107.916 142.677 172.518 1.00 52.59  ? 25  ASP A CG  1 
ATOM   132   O OD1 . ASP A 1 25  ? 108.349 141.832 171.708 1.00 52.59  ? 25  ASP A OD1 1 
ATOM   133   O OD2 . ASP A 1 25  ? 106.910 142.481 173.230 1.00 52.59  ? 25  ASP A OD2 1 
ATOM   134   N N   . ALA A 1 26  ? 110.762 142.837 170.159 1.00 48.57  ? 26  ALA A N   1 
ATOM   135   C CA  . ALA A 1 26  ? 110.973 142.739 168.723 1.00 48.57  ? 26  ALA A CA  1 
ATOM   136   C C   . ALA A 1 26  ? 109.724 142.311 167.967 1.00 48.57  ? 26  ALA A C   1 
ATOM   137   O O   . ALA A 1 26  ? 109.755 142.244 166.734 1.00 48.57  ? 26  ALA A O   1 
ATOM   138   C CB  . ALA A 1 26  ? 112.114 141.763 168.423 1.00 48.57  ? 26  ALA A CB  1 
ATOM   139   N N   . ARG A 1 27  ? 108.633 142.020 168.667 1.00 51.55  ? 27  ARG A N   1 
ATOM   140   C CA  . ARG A 1 27  ? 107.399 141.568 168.041 1.00 51.55  ? 27  ARG A CA  1 
ATOM   141   C C   . ARG A 1 27  ? 106.442 142.708 167.721 1.00 51.55  ? 27  ARG A C   1 
ATOM   142   O O   . ARG A 1 27  ? 105.356 142.454 167.192 1.00 51.55  ? 27  ARG A O   1 
ATOM   143   C CB  . ARG A 1 27  ? 106.702 140.544 168.943 1.00 51.55  ? 27  ARG A CB  1 
ATOM   144   C CG  . ARG A 1 27  ? 107.406 139.198 169.010 1.00 51.55  ? 27  ARG A CG  1 
ATOM   145   C CD  . ARG A 1 27  ? 107.310 138.572 170.394 1.00 51.55  ? 27  ARG A CD  1 
ATOM   146   N NE  . ARG A 1 27  ? 105.950 138.577 170.918 1.00 51.55  ? 27  ARG A NE  1 
ATOM   147   C CZ  . ARG A 1 27  ? 105.572 139.229 172.009 1.00 51.55  ? 27  ARG A CZ  1 
ATOM   148   N NH1 . ARG A 1 27  ? 106.430 139.938 172.722 1.00 51.55  ? 27  ARG A NH1 1 
ATOM   149   N NH2 . ARG A 1 27  ? 104.301 139.166 172.395 1.00 51.55  ? 27  ARG A NH2 1 
ATOM   150   N N   . ILE A 1 28  ? 106.812 143.949 168.025 1.00 49.05  ? 28  ILE A N   1 
ATOM   151   C CA  . ILE A 1 28  ? 105.951 145.107 167.825 1.00 49.05  ? 28  ILE A CA  1 
ATOM   152   C C   . ILE A 1 28  ? 106.719 146.146 167.023 1.00 49.05  ? 28  ILE A C   1 
ATOM   153   O O   . ILE A 1 28  ? 107.881 146.432 167.327 1.00 49.05  ? 28  ILE A O   1 
ATOM   154   C CB  . ILE A 1 28  ? 105.478 145.695 169.166 1.00 49.05  ? 28  ILE A CB  1 
ATOM   155   C CG1 . ILE A 1 28  ? 104.574 144.698 169.889 1.00 49.05  ? 28  ILE A CG1 1 
ATOM   156   C CG2 . ILE A 1 28  ? 104.751 147.005 168.950 1.00 49.05  ? 28  ILE A CG2 1 
ATOM   157   C CD1 . ILE A 1 28  ? 104.103 145.173 171.237 1.00 49.05  ? 28  ILE A CD1 1 
ATOM   158   N N   . ARG A 1 29  ? 106.076 146.704 166.001 1.00 47.38  ? 29  ARG A N   1 
ATOM   159   C CA  . ARG A 1 29  ? 106.720 147.713 165.179 1.00 47.38  ? 29  ARG A CA  1 
ATOM   160   C C   . ARG A 1 29  ? 106.943 148.990 165.987 1.00 47.38  ? 29  ARG A C   1 
ATOM   161   O O   . ARG A 1 29  ? 106.246 149.243 166.971 1.00 47.38  ? 29  ARG A O   1 
ATOM   162   C CB  . ARG A 1 29  ? 105.877 148.007 163.941 1.00 47.38  ? 29  ARG A CB  1 
ATOM   163   C CG  . ARG A 1 29  ? 104.642 148.854 164.195 1.00 47.38  ? 29  ARG A CG  1 
ATOM   164   C CD  . ARG A 1 29  ? 104.065 149.361 162.884 1.00 47.38  ? 29  ARG A CD  1 
ATOM   165   N NE  . ARG A 1 29  ? 102.819 150.094 163.069 1.00 47.38  ? 29  ARG A NE  1 
ATOM   166   C CZ  . ARG A 1 29  ? 102.745 151.396 163.305 1.00 47.38  ? 29  ARG A CZ  1 
ATOM   167   N NH1 . ARG A 1 29  ? 103.832 152.142 163.404 1.00 47.38  ? 29  ARG A NH1 1 
ATOM   168   N NH2 . ARG A 1 29  ? 101.551 151.963 163.445 1.00 47.38  ? 29  ARG A NH2 1 
ATOM   169   N N   . PRO A 1 30  ? 107.928 149.803 165.601 1.00 46.88  ? 30  PRO A N   1 
ATOM   170   C CA  . PRO A 1 30  ? 108.166 151.058 166.321 1.00 46.88  ? 30  PRO A CA  1 
ATOM   171   C C   . PRO A 1 30  ? 106.979 151.999 166.201 1.00 46.88  ? 30  PRO A C   1 
ATOM   172   O O   . PRO A 1 30  ? 106.236 151.972 165.218 1.00 46.88  ? 30  PRO A O   1 
ATOM   173   C CB  . PRO A 1 30  ? 109.408 151.633 165.632 1.00 46.88  ? 30  PRO A CB  1 
ATOM   174   C CG  . PRO A 1 30  ? 109.426 150.996 164.295 1.00 46.88  ? 30  PRO A CG  1 
ATOM   175   C CD  . PRO A 1 30  ? 108.891 149.616 164.506 1.00 46.88  ? 30  PRO A CD  1 
ATOM   176   N N   . ASN A 1 31  ? 106.818 152.837 167.223 1.00 57.63  ? 31  ASN A N   1 
ATOM   177   C CA  . ASN A 1 31  ? 105.688 153.757 167.378 1.00 57.63  ? 31  ASN A CA  1 
ATOM   178   C C   . ASN A 1 31  ? 104.372 153.082 166.991 1.00 57.63  ? 31  ASN A C   1 
ATOM   179   O O   . ASN A 1 31  ? 103.674 153.484 166.060 1.00 57.63  ? 31  ASN A O   1 
ATOM   180   C CB  . ASN A 1 31  ? 105.902 155.061 166.603 1.00 57.63  ? 31  ASN A CB  1 
ATOM   181   C CG  . ASN A 1 31  ? 106.359 154.839 165.181 1.00 57.63  ? 31  ASN A CG  1 
ATOM   182   O OD1 . ASN A 1 31  ? 105.550 154.602 164.287 1.00 57.63  ? 31  ASN A OD1 1 
ATOM   183   N ND2 . ASN A 1 31  ? 107.666 154.910 164.962 1.00 57.63  ? 31  ASN A ND2 1 
ATOM   184   N N   . PHE A 1 32  ? 104.055 152.024 167.734 1.00 62.09  ? 32  PHE A N   1 
ATOM   185   C CA  . PHE A 1 32  ? 102.824 151.281 167.510 1.00 62.09  ? 32  PHE A CA  1 
ATOM   186   C C   . PHE A 1 32  ? 101.611 152.173 167.737 1.00 62.09  ? 32  PHE A C   1 
ATOM   187   O O   . PHE A 1 32  ? 101.602 153.020 168.634 1.00 62.09  ? 32  PHE A O   1 
ATOM   188   C CB  . PHE A 1 32  ? 102.773 150.072 168.443 1.00 62.09  ? 32  PHE A CB  1 
ATOM   189   C CG  . PHE A 1 32  ? 101.606 149.167 168.201 1.00 62.09  ? 32  PHE A CG  1 
ATOM   190   C CD1 . PHE A 1 32  ? 101.575 148.334 167.096 1.00 62.09  ? 32  PHE A CD1 1 
ATOM   191   C CD2 . PHE A 1 32  ? 100.546 149.135 169.088 1.00 62.09  ? 32  PHE A CD2 1 
ATOM   192   C CE1 . PHE A 1 32  ? 100.501 147.494 166.874 1.00 62.09  ? 32  PHE A CE1 1 
ATOM   193   C CE2 . PHE A 1 32  ? 99.470  148.298 168.873 1.00 62.09  ? 32  PHE A CE2 1 
ATOM   194   C CZ  . PHE A 1 32  ? 99.448  147.476 167.764 1.00 62.09  ? 32  PHE A CZ  1 
ATOM   195   N N   . LYS A 1 33  ? 100.583 151.979 166.907 1.00 60.10  ? 33  LYS A N   1 
ATOM   196   C CA  . LYS A 1 33  ? 99.359  152.781 166.943 1.00 60.10  ? 33  LYS A CA  1 
ATOM   197   C C   . LYS A 1 33  ? 99.697  154.266 166.770 1.00 60.10  ? 33  LYS A C   1 
ATOM   198   O O   . LYS A 1 33  ? 99.561  155.089 167.676 1.00 60.10  ? 33  LYS A O   1 
ATOM   199   C CB  . LYS A 1 33  ? 98.569  152.512 168.232 1.00 60.10  ? 33  LYS A CB  1 
ATOM   200   C CG  . LYS A 1 33  ? 97.070  152.833 168.166 1.00 60.10  ? 33  LYS A CG  1 
ATOM   201   C CD  . LYS A 1 33  ? 96.761  154.295 168.467 1.00 60.10  ? 33  LYS A CD  1 
ATOM   202   C CE  . LYS A 1 33  ? 95.269  154.581 168.411 1.00 60.10  ? 33  LYS A CE  1 
ATOM   203   N NZ  . LYS A 1 33  ? 94.995  156.023 168.159 1.00 60.10  ? 33  LYS A NZ  1 
ATOM   204   N N   . GLY A 1 34  ? 100.198 154.572 165.578 1.00 54.06  ? 34  GLY A N   1 
ATOM   205   C CA  . GLY A 1 34  ? 100.573 155.921 165.235 1.00 54.06  ? 34  GLY A CA  1 
ATOM   206   C C   . GLY A 1 34  ? 100.867 156.073 163.758 1.00 54.06  ? 34  GLY A C   1 
ATOM   207   O O   . GLY A 1 34  ? 100.337 155.341 162.917 1.00 54.06  ? 34  GLY A O   1 
ATOM   208   N N   . PRO A 1 35  ? 101.718 157.041 163.412 1.00 50.73  ? 35  PRO A N   1 
ATOM   209   C CA  . PRO A 1 35  ? 102.080 157.219 162.010 1.00 50.73  ? 35  PRO A CA  1 
ATOM   210   C C   . PRO A 1 35  ? 102.848 156.015 161.498 1.00 50.73  ? 35  PRO A C   1 
ATOM   211   O O   . PRO A 1 35  ? 103.589 155.366 162.255 1.00 50.73  ? 35  PRO A O   1 
ATOM   212   C CB  . PRO A 1 35  ? 102.961 158.481 162.031 1.00 50.73  ? 35  PRO A CB  1 
ATOM   213   C CG  . PRO A 1 35  ? 103.515 158.520 163.409 1.00 50.73  ? 35  PRO A CG  1 
ATOM   214   C CD  . PRO A 1 35  ? 102.435 157.975 164.296 1.00 50.73  ? 35  PRO A CD  1 
ATOM   215   N N   . PRO A 1 36  ? 102.697 155.672 160.221 1.00 45.97  ? 36  PRO A N   1 
ATOM   216   C CA  . PRO A 1 36  ? 103.406 154.504 159.687 1.00 45.97  ? 36  PRO A CA  1 
ATOM   217   C C   . PRO A 1 36  ? 104.904 154.744 159.621 1.00 45.97  ? 36  PRO A C   1 
ATOM   218   O O   . PRO A 1 36  ? 105.363 155.825 159.249 1.00 45.97  ? 36  PRO A O   1 
ATOM   219   C CB  . PRO A 1 36  ? 102.805 154.337 158.289 1.00 45.97  ? 36  PRO A CB  1 
ATOM   220   C CG  . PRO A 1 36  ? 102.336 155.702 157.923 1.00 45.97  ? 36  PRO A CG  1 
ATOM   221   C CD  . PRO A 1 36  ? 101.871 156.336 159.200 1.00 45.97  ? 36  PRO A CD  1 
ATOM   222   N N   . VAL A 1 37  ? 105.670 153.713 159.980 1.00 39.53  ? 37  VAL A N   1 
ATOM   223   C CA  . VAL A 1 37  ? 107.123 153.812 159.934 1.00 39.53  ? 37  VAL A CA  1 
ATOM   224   C C   . VAL A 1 37  ? 107.587 153.765 158.486 1.00 39.53  ? 37  VAL A C   1 
ATOM   225   O O   . VAL A 1 37  ? 107.202 152.873 157.720 1.00 39.53  ? 37  VAL A O   1 
ATOM   226   C CB  . VAL A 1 37  ? 107.769 152.698 160.770 1.00 39.53  ? 37  VAL A CB  1 
ATOM   227   C CG1 . VAL A 1 37  ? 107.206 151.342 160.389 1.00 39.53  ? 37  VAL A CG1 1 
ATOM   228   C CG2 . VAL A 1 37  ? 109.272 152.710 160.585 1.00 39.53  ? 37  VAL A CG2 1 
ATOM   229   N N   . ASN A 1 38  ? 108.409 154.733 158.100 1.00 37.04  ? 38  ASN A N   1 
ATOM   230   C CA  . ASN A 1 38  ? 108.903 154.831 156.737 1.00 37.04  ? 38  ASN A CA  1 
ATOM   231   C C   . ASN A 1 38  ? 110.258 154.147 156.620 1.00 37.04  ? 38  ASN A C   1 
ATOM   232   O O   . ASN A 1 38  ? 111.056 154.143 157.559 1.00 37.04  ? 38  ASN A O   1 
ATOM   233   C CB  . ASN A 1 38  ? 109.005 156.294 156.299 1.00 37.04  ? 38  ASN A CB  1 
ATOM   234   C CG  . ASN A 1 38  ? 109.773 157.153 157.290 1.00 37.04  ? 38  ASN A CG  1 
ATOM   235   O OD1 . ASN A 1 38  ? 110.953 156.911 157.543 1.00 37.04  ? 38  ASN A OD1 1 
ATOM   236   N ND2 . ASN A 1 38  ? 109.114 158.166 157.857 1.00 37.04  ? 38  ASN A ND2 1 
ATOM   237   N N   . VAL A 1 39  ? 110.503 153.551 155.457 1.00 34.87  ? 39  VAL A N   1 
ATOM   238   C CA  . VAL A 1 39  ? 111.745 152.842 155.176 1.00 34.87  ? 39  VAL A CA  1 
ATOM   239   C C   . VAL A 1 39  ? 112.317 153.391 153.879 1.00 34.87  ? 39  VAL A C   1 
ATOM   240   O O   . VAL A 1 39  ? 111.663 153.323 152.833 1.00 34.87  ? 39  VAL A O   1 
ATOM   241   C CB  . VAL A 1 39  ? 111.529 151.325 155.068 1.00 34.87  ? 39  VAL A CB  1 
ATOM   242   C CG1 . VAL A 1 39  ? 112.771 150.657 154.521 1.00 34.87  ? 39  VAL A CG1 1 
ATOM   243   C CG2 . VAL A 1 39  ? 111.161 150.749 156.418 1.00 34.87  ? 39  VAL A CG2 1 
ATOM   244   N N   . THR A 1 40  ? 113.532 153.926 153.943 1.00 47.29  ? 40  THR A N   1 
ATOM   245   C CA  . THR A 1 40  ? 114.201 154.495 152.773 1.00 47.29  ? 40  THR A CA  1 
ATOM   246   C C   . THR A 1 40  ? 115.229 153.480 152.289 1.00 47.29  ? 40  THR A C   1 
ATOM   247   O O   . THR A 1 40  ? 116.406 153.547 152.639 1.00 47.29  ? 40  THR A O   1 
ATOM   248   C CB  . THR A 1 40  ? 114.849 155.830 153.111 1.00 47.29  ? 40  THR A CB  1 
ATOM   249   O OG1 . THR A 1 40  ? 115.983 155.608 153.956 1.00 47.29  ? 40  THR A OG1 1 
ATOM   250   C CG2 . THR A 1 40  ? 113.861 156.729 153.831 1.00 47.29  ? 40  THR A CG2 1 
ATOM   251   N N   . CYS A 1 41  ? 114.779 152.537 151.468 1.00 35.78  ? 41  CYS A N   1 
ATOM   252   C CA  . CYS A 1 41  ? 115.627 151.444 151.016 1.00 35.78  ? 41  CYS A CA  1 
ATOM   253   C C   . CYS A 1 41  ? 116.331 151.801 149.716 1.00 35.78  ? 41  CYS A C   1 
ATOM   254   O O   . CYS A 1 41  ? 115.766 152.477 148.853 1.00 35.78  ? 41  CYS A O   1 
ATOM   255   C CB  . CYS A 1 41  ? 114.806 150.169 150.829 1.00 35.78  ? 41  CYS A CB  1 
ATOM   256   S SG  . CYS A 1 41  ? 113.601 150.247 149.496 1.00 35.78  ? 41  CYS A SG  1 
ATOM   257   N N   . ASN A 1 42  ? 117.578 151.353 149.591 1.00 38.47  ? 42  ASN A N   1 
ATOM   258   C CA  . ASN A 1 42  ? 118.346 151.481 148.363 1.00 38.47  ? 42  ASN A CA  1 
ATOM   259   C C   . ASN A 1 42  ? 119.073 150.171 148.109 1.00 38.47  ? 42  ASN A C   1 
ATOM   260   O O   . ASN A 1 42  ? 119.376 149.425 149.043 1.00 38.47  ? 42  ASN A O   1 
ATOM   261   C CB  . ASN A 1 42  ? 119.344 152.640 148.430 1.00 38.47  ? 42  ASN A CB  1 
ATOM   262   C CG  . ASN A 1 42  ? 120.468 152.384 149.402 1.00 38.47  ? 42  ASN A CG  1 
ATOM   263   O OD1 . ASN A 1 42  ? 120.290 151.704 150.410 1.00 38.47  ? 42  ASN A OD1 1 
ATOM   264   N ND2 . ASN A 1 42  ? 121.639 152.931 149.107 1.00 38.47  ? 42  ASN A ND2 1 
ATOM   265   N N   . ILE A 1 43  ? 119.352 149.892 146.839 1.00 47.29  ? 43  ILE A N   1 
ATOM   266   C CA  . ILE A 1 43  ? 119.866 148.594 146.421 1.00 47.29  ? 43  ILE A CA  1 
ATOM   267   C C   . ILE A 1 43  ? 121.145 148.794 145.622 1.00 47.29  ? 43  ILE A C   1 
ATOM   268   O O   . ILE A 1 43  ? 121.187 149.621 144.706 1.00 47.29  ? 43  ILE A O   1 
ATOM   269   C CB  . ILE A 1 43  ? 118.827 147.816 145.593 1.00 47.29  ? 43  ILE A CB  1 
ATOM   270   C CG1 . ILE A 1 43  ? 119.497 146.702 144.798 1.00 47.29  ? 43  ILE A CG1 1 
ATOM   271   C CG2 . ILE A 1 43  ? 118.082 148.745 144.663 1.00 47.29  ? 43  ILE A CG2 1 
ATOM   272   C CD1 . ILE A 1 43  ? 118.570 146.020 143.837 1.00 47.29  ? 43  ILE A CD1 1 
ATOM   273   N N   . PHE A 1 44  ? 122.182 148.041 145.973 1.00 39.47  ? 44  PHE A N   1 
ATOM   274   C CA  . PHE A 1 44  ? 123.440 148.016 145.241 1.00 39.47  ? 44  PHE A CA  1 
ATOM   275   C C   . PHE A 1 44  ? 123.558 146.684 144.519 1.00 39.47  ? 44  PHE A C   1 
ATOM   276   O O   . PHE A 1 44  ? 123.490 145.627 145.151 1.00 39.47  ? 44  PHE A O   1 
ATOM   277   C CB  . PHE A 1 44  ? 124.625 148.217 146.189 1.00 39.47  ? 44  PHE A CB  1 
ATOM   278   C CG  . PHE A 1 44  ? 125.972 148.055 145.537 1.00 39.47  ? 44  PHE A CG  1 
ATOM   279   C CD1 . PHE A 1 44  ? 126.554 146.807 145.411 1.00 39.47  ? 44  PHE A CD1 1 
ATOM   280   C CD2 . PHE A 1 44  ? 126.662 149.154 145.064 1.00 39.47  ? 44  PHE A CD2 1 
ATOM   281   C CE1 . PHE A 1 44  ? 127.788 146.659 144.819 1.00 39.47  ? 44  PHE A CE1 1 
ATOM   282   C CE2 . PHE A 1 44  ? 127.898 149.009 144.472 1.00 39.47  ? 44  PHE A CE2 1 
ATOM   283   C CZ  . PHE A 1 44  ? 128.461 147.761 144.350 1.00 39.47  ? 44  PHE A CZ  1 
ATOM   284   N N   . ILE A 1 45  ? 123.749 146.735 143.208 1.00 32.98  ? 45  ILE A N   1 
ATOM   285   C CA  . ILE A 1 45  ? 123.873 145.531 142.396 1.00 32.98  ? 45  ILE A CA  1 
ATOM   286   C C   . ILE A 1 45  ? 125.333 145.108 142.369 1.00 32.98  ? 45  ILE A C   1 
ATOM   287   O O   . ILE A 1 45  ? 126.223 145.926 142.111 1.00 32.98  ? 45  ILE A O   1 
ATOM   288   C CB  . ILE A 1 45  ? 123.341 145.767 140.975 1.00 32.98  ? 45  ILE A CB  1 
ATOM   289   C CG1 . ILE A 1 45  ? 121.821 145.884 140.996 1.00 32.98  ? 45  ILE A CG1 1 
ATOM   290   C CG2 . ILE A 1 45  ? 123.763 144.644 140.057 1.00 32.98  ? 45  ILE A CG2 1 
ATOM   291   C CD1 . ILE A 1 45  ? 121.226 146.111 139.641 1.00 32.98  ? 45  ILE A CD1 1 
ATOM   292   N N   . ASN A 1 46  ? 125.584 143.831 142.646 1.00 29.15  ? 46  ASN A N   1 
ATOM   293   C CA  . ASN A 1 46  ? 126.933 143.282 142.644 1.00 29.15  ? 46  ASN A CA  1 
ATOM   294   C C   . ASN A 1 46  ? 127.197 142.434 141.408 1.00 29.15  ? 46  ASN A C   1 
ATOM   295   O O   . ASN A 1 46  ? 128.229 142.597 140.752 1.00 29.15  ? 46  ASN A O   1 
ATOM   296   C CB  . ASN A 1 46  ? 127.158 142.458 143.918 1.00 29.15  ? 46  ASN A CB  1 
ATOM   297   C CG  . ASN A 1 46  ? 128.590 141.977 144.069 1.00 29.15  ? 46  ASN A CG  1 
ATOM   298   O OD1 . ASN A 1 46  ? 129.175 141.402 143.152 1.00 29.15  ? 46  ASN A OD1 1 
ATOM   299   N ND2 . ASN A 1 46  ? 129.163 142.218 145.240 1.00 29.15  ? 46  ASN A ND2 1 
ATOM   300   N N   . SER A 1 47  ? 126.284 141.528 141.079 1.00 32.85  ? 47  SER A N   1 
ATOM   301   C CA  . SER A 1 47  ? 126.403 140.688 139.900 1.00 32.85  ? 47  SER A CA  1 
ATOM   302   C C   . SER A 1 47  ? 125.124 140.780 139.085 1.00 32.85  ? 47  SER A C   1 
ATOM   303   O O   . SER A 1 47  ? 124.059 141.119 139.607 1.00 32.85  ? 47  SER A O   1 
ATOM   304   C CB  . SER A 1 47  ? 126.679 139.227 140.267 1.00 32.85  ? 47  SER A CB  1 
ATOM   305   O OG  . SER A 1 47  ? 126.749 138.417 139.107 1.00 32.85  ? 47  SER A OG  1 
ATOM   306   N N   . PHE A 1 48  ? 125.240 140.475 137.797 1.00 33.47  ? 48  PHE A N   1 
ATOM   307   C CA  . PHE A 1 48  ? 124.104 140.559 136.884 1.00 33.47  ? 48  PHE A CA  1 
ATOM   308   C C   . PHE A 1 48  ? 124.422 139.696 135.678 1.00 33.47  ? 48  PHE A C   1 
ATOM   309   O O   . PHE A 1 48  ? 125.475 139.870 135.058 1.00 33.47  ? 48  PHE A O   1 
ATOM   310   C CB  . PHE A 1 48  ? 123.855 142.009 136.473 1.00 33.47  ? 48  PHE A CB  1 
ATOM   311   C CG  . PHE A 1 48  ? 122.445 142.294 136.048 1.00 33.47  ? 48  PHE A CG  1 
ATOM   312   C CD1 . PHE A 1 48  ? 121.777 141.448 135.184 1.00 33.47  ? 48  PHE A CD1 1 
ATOM   313   C CD2 . PHE A 1 48  ? 121.791 143.421 136.509 1.00 33.47  ? 48  PHE A CD2 1 
ATOM   314   C CE1 . PHE A 1 48  ? 120.486 141.719 134.793 1.00 33.47  ? 48  PHE A CE1 1 
ATOM   315   C CE2 . PHE A 1 48  ? 120.499 143.695 136.121 1.00 33.47  ? 48  PHE A CE2 1 
ATOM   316   C CZ  . PHE A 1 48  ? 119.846 142.844 135.263 1.00 33.47  ? 48  PHE A CZ  1 
ATOM   317   N N   . GLY A 1 49  ? 123.533 138.768 135.347 1.00 32.93  ? 49  GLY A N   1 
ATOM   318   C CA  . GLY A 1 49  ? 123.774 137.904 134.213 1.00 32.93  ? 49  GLY A CA  1 
ATOM   319   C C   . GLY A 1 49  ? 122.849 136.705 134.236 1.00 32.93  ? 49  GLY A C   1 
ATOM   320   O O   . GLY A 1 49  ? 121.851 136.680 134.958 1.00 32.93  ? 49  GLY A O   1 
ATOM   321   N N   . SER A 1 50  ? 123.211 135.712 133.422 1.00 34.30  ? 50  SER A N   1 
ATOM   322   C CA  . SER A 1 50  ? 122.421 134.494 133.250 1.00 34.30  ? 50  SER A CA  1 
ATOM   323   C C   . SER A 1 50  ? 120.993 134.810 132.825 1.00 34.30  ? 50  SER A C   1 
ATOM   324   O O   . SER A 1 50  ? 120.053 134.102 133.192 1.00 34.30  ? 50  SER A O   1 
ATOM   325   C CB  . SER A 1 50  ? 122.422 133.640 134.519 1.00 34.30  ? 50  SER A CB  1 
ATOM   326   O OG  . SER A 1 50  ? 121.522 132.552 134.397 1.00 34.30  ? 50  SER A OG  1 
ATOM   327   N N   . ILE A 1 51  ? 120.822 135.876 132.052 1.00 34.36  ? 51  ILE A N   1 
ATOM   328   C CA  . ILE A 1 51  ? 119.508 136.296 131.585 1.00 34.36  ? 51  ILE A CA  1 
ATOM   329   C C   . ILE A 1 51  ? 119.194 135.514 130.315 1.00 34.36  ? 51  ILE A C   1 
ATOM   330   O O   . ILE A 1 51  ? 119.811 135.727 129.269 1.00 34.36  ? 51  ILE A O   1 
ATOM   331   C CB  . ILE A 1 51  ? 119.452 137.810 131.349 1.00 34.36  ? 51  ILE A CB  1 
ATOM   332   C CG1 . ILE A 1 51  ? 118.239 138.178 130.498 1.00 34.36  ? 51  ILE A CG1 1 
ATOM   333   C CG2 . ILE A 1 51  ? 120.742 138.311 130.725 1.00 34.36  ? 51  ILE A CG2 1 
ATOM   334   C CD1 . ILE A 1 51  ? 118.005 139.660 130.410 1.00 34.36  ? 51  ILE A CD1 1 
ATOM   335   N N   . ALA A 1 52  ? 118.243 134.591 130.413 1.00 39.88  ? 52  ALA A N   1 
ATOM   336   C CA  . ALA A 1 52  ? 117.869 133.722 129.308 1.00 39.88  ? 52  ALA A CA  1 
ATOM   337   C C   . ALA A 1 52  ? 116.396 133.917 128.997 1.00 39.88  ? 52  ALA A C   1 
ATOM   338   O O   . ALA A 1 52  ? 115.563 133.933 129.909 1.00 39.88  ? 52  ALA A O   1 
ATOM   339   C CB  . ALA A 1 52  ? 118.151 132.256 129.640 1.00 39.88  ? 52  ALA A CB  1 
ATOM   340   N N   . GLU A 1 53  ? 116.077 134.062 127.713 1.00 48.38  ? 53  GLU A N   1 
ATOM   341   C CA  . GLU A 1 53  ? 114.692 134.214 127.296 1.00 48.38  ? 53  GLU A CA  1 
ATOM   342   C C   . GLU A 1 53  ? 113.946 132.891 127.232 1.00 48.38  ? 53  GLU A C   1 
ATOM   343   O O   . GLU A 1 53  ? 112.726 132.899 127.038 1.00 48.38  ? 53  GLU A O   1 
ATOM   344   C CB  . GLU A 1 53  ? 114.628 134.907 125.934 1.00 48.38  ? 53  GLU A CB  1 
ATOM   345   C CG  . GLU A 1 53  ? 115.669 135.995 125.751 1.00 48.38  ? 53  GLU A CG  1 
ATOM   346   C CD  . GLU A 1 53  ? 116.840 135.544 124.903 1.00 48.38  ? 53  GLU A CD  1 
ATOM   347   O OE1 . GLU A 1 53  ? 117.037 134.319 124.766 1.00 48.38  ? 53  GLU A OE1 1 
ATOM   348   O OE2 . GLU A 1 53  ? 117.565 136.414 124.377 1.00 48.38  ? 53  GLU A OE2 1 
ATOM   349   N N   . THR A 1 54  ? 114.641 131.763 127.398 1.00 49.90  ? 54  THR A N   1 
ATOM   350   C CA  . THR A 1 54  ? 113.984 130.465 127.290 1.00 49.90  ? 54  THR A CA  1 
ATOM   351   C C   . THR A 1 54  ? 112.912 130.293 128.358 1.00 49.90  ? 54  THR A C   1 
ATOM   352   O O   . THR A 1 54  ? 111.808 129.818 128.067 1.00 49.90  ? 54  THR A O   1 
ATOM   353   C CB  . THR A 1 54  ? 115.017 129.343 127.389 1.00 49.90  ? 54  THR A CB  1 
ATOM   354   O OG1 . THR A 1 54  ? 116.006 129.513 126.367 1.00 49.90  ? 54  THR A OG1 1 
ATOM   355   C CG2 . THR A 1 54  ? 114.349 127.988 127.218 1.00 49.90  ? 54  THR A CG2 1 
ATOM   356   N N   . THR A 1 55  ? 113.212 130.679 129.597 1.00 44.39  ? 55  THR A N   1 
ATOM   357   C CA  . THR A 1 55  ? 112.264 130.540 130.695 1.00 44.39  ? 55  THR A CA  1 
ATOM   358   C C   . THR A 1 55  ? 111.887 131.876 131.323 1.00 44.39  ? 55  THR A C   1 
ATOM   359   O O   . THR A 1 55  ? 111.315 131.892 132.419 1.00 44.39  ? 55  THR A O   1 
ATOM   360   C CB  . THR A 1 55  ? 112.817 129.592 131.763 1.00 44.39  ? 55  THR A CB  1 
ATOM   361   O OG1 . THR A 1 55  ? 111.836 129.404 132.791 1.00 44.39  ? 55  THR A OG1 1 
ATOM   362   C CG2 . THR A 1 55  ? 114.089 130.147 132.369 1.00 44.39  ? 55  THR A CG2 1 
ATOM   363   N N   . MET A 1 56  ? 112.197 132.992 130.661 1.00 42.84  ? 56  MET A N   1 
ATOM   364   C CA  . MET A 1 56  ? 111.695 134.315 131.033 1.00 42.84  ? 56  MET A CA  1 
ATOM   365   C C   . MET A 1 56  ? 112.149 134.713 132.440 1.00 42.84  ? 56  MET A C   1 
ATOM   366   O O   . MET A 1 56  ? 111.337 134.974 133.329 1.00 42.84  ? 56  MET A O   1 
ATOM   367   C CB  . MET A 1 56  ? 110.167 134.355 130.928 1.00 42.84  ? 56  MET A CB  1 
ATOM   368   C CG  . MET A 1 56  ? 109.616 134.034 129.550 1.00 42.84  ? 56  MET A CG  1 
ATOM   369   S SD  . MET A 1 56  ? 109.825 135.363 128.360 1.00 42.84  ? 56  MET A SD  1 
ATOM   370   C CE  . MET A 1 56  ? 108.640 134.881 127.107 1.00 42.84  ? 56  MET A CE  1 
ATOM   371   N N   . ASP A 1 57  ? 113.464 134.767 132.632 1.00 35.81  ? 57  ASP A N   1 
ATOM   372   C CA  . ASP A 1 57  ? 113.994 135.104 133.946 1.00 35.81  ? 57  ASP A CA  1 
ATOM   373   C C   . ASP A 1 57  ? 115.407 135.652 133.811 1.00 35.81  ? 57  ASP A C   1 
ATOM   374   O O   . ASP A 1 57  ? 115.996 135.662 132.729 1.00 35.81  ? 57  ASP A O   1 
ATOM   375   C CB  . ASP A 1 57  ? 113.971 133.892 134.886 1.00 35.81  ? 57  ASP A CB  1 
ATOM   376   C CG  . ASP A 1 57  ? 114.899 132.778 134.438 1.00 35.81  ? 57  ASP A CG  1 
ATOM   377   O OD1 . ASP A 1 57  ? 115.426 132.844 133.308 1.00 35.81  ? 57  ASP A OD1 1 
ATOM   378   O OD2 . ASP A 1 57  ? 115.102 131.827 135.222 1.00 35.81  ? 57  ASP A OD2 1 
ATOM   379   N N   . TYR A 1 58  ? 115.939 136.108 134.941 1.00 28.12  ? 58  TYR A N   1 
ATOM   380   C CA  . TYR A 1 58  ? 117.307 136.592 135.051 1.00 28.12  ? 58  TYR A CA  1 
ATOM   381   C C   . TYR A 1 58  ? 117.678 136.572 136.524 1.00 28.12  ? 58  TYR A C   1 
ATOM   382   O O   . TYR A 1 58  ? 116.806 136.522 137.394 1.00 28.12  ? 58  TYR A O   1 
ATOM   383   C CB  . TYR A 1 58  ? 117.457 137.998 134.466 1.00 28.12  ? 58  TYR A CB  1 
ATOM   384   C CG  . TYR A 1 58  ? 116.863 139.086 135.323 1.00 28.12  ? 58  TYR A CG  1 
ATOM   385   C CD1 . TYR A 1 58  ? 115.512 139.101 135.620 1.00 28.12  ? 58  TYR A CD1 1 
ATOM   386   C CD2 . TYR A 1 58  ? 117.651 140.108 135.824 1.00 28.12  ? 58  TYR A CD2 1 
ATOM   387   C CE1 . TYR A 1 58  ? 114.967 140.093 136.401 1.00 28.12  ? 58  TYR A CE1 1 
ATOM   388   C CE2 . TYR A 1 58  ? 117.111 141.107 136.603 1.00 28.12  ? 58  TYR A CE2 1 
ATOM   389   C CZ  . TYR A 1 58  ? 115.768 141.094 136.887 1.00 28.12  ? 58  TYR A CZ  1 
ATOM   390   O OH  . TYR A 1 58  ? 115.221 142.086 137.664 1.00 28.12  ? 58  TYR A OH  1 
ATOM   391   N N   . ARG A 1 59  ? 118.978 136.605 136.804 1.00 29.58  ? 59  ARG A N   1 
ATOM   392   C CA  . ARG A 1 59  ? 119.445 136.539 138.181 1.00 29.58  ? 59  ARG A CA  1 
ATOM   393   C C   . ARG A 1 59  ? 120.355 137.717 138.491 1.00 29.58  ? 59  ARG A C   1 
ATOM   394   O O   . ARG A 1 59  ? 121.097 138.188 137.625 1.00 29.58  ? 59  ARG A O   1 
ATOM   395   C CB  . ARG A 1 59  ? 120.167 135.218 138.472 1.00 29.58  ? 59  ARG A CB  1 
ATOM   396   C CG  . ARG A 1 59  ? 121.634 135.183 138.101 1.00 29.58  ? 59  ARG A CG  1 
ATOM   397   C CD  . ARG A 1 59  ? 122.301 133.930 138.644 1.00 29.58  ? 59  ARG A CD  1 
ATOM   398   N NE  . ARG A 1 59  ? 121.732 132.714 138.074 1.00 29.58  ? 59  ARG A NE  1 
ATOM   399   C CZ  . ARG A 1 59  ? 120.879 131.919 138.704 1.00 29.58  ? 59  ARG A CZ  1 
ATOM   400   N NH1 . ARG A 1 59  ? 120.477 132.176 139.937 1.00 29.58  ? 59  ARG A NH1 1 
ATOM   401   N NH2 . ARG A 1 59  ? 120.419 130.838 138.081 1.00 29.58  ? 59  ARG A NH2 1 
ATOM   402   N N   . VAL A 1 60  ? 120.273 138.203 139.731 1.00 30.72  ? 60  VAL A N   1 
ATOM   403   C CA  . VAL A 1 60  ? 121.069 139.331 140.194 1.00 30.72  ? 60  VAL A CA  1 
ATOM   404   C C   . VAL A 1 60  ? 121.585 139.033 141.595 1.00 30.72  ? 60  VAL A C   1 
ATOM   405   O O   . VAL A 1 60  ? 121.051 138.187 142.313 1.00 30.72  ? 60  VAL A O   1 
ATOM   406   C CB  . VAL A 1 60  ? 120.265 140.647 140.200 1.00 30.72  ? 60  VAL A CB  1 
ATOM   407   C CG1 . VAL A 1 60  ? 120.003 141.113 138.786 1.00 30.72  ? 60  VAL A CG1 1 
ATOM   408   C CG2 . VAL A 1 60  ? 118.963 140.458 140.938 1.00 30.72  ? 60  VAL A CG2 1 
ATOM   409   N N   . ASN A 1 61  ? 122.645 139.742 141.975 1.00 36.58  ? 61  ASN A N   1 
ATOM   410   C CA  . ASN A 1 61  ? 123.173 139.730 143.336 1.00 36.58  ? 61  ASN A CA  1 
ATOM   411   C C   . ASN A 1 61  ? 123.149 141.163 143.844 1.00 36.58  ? 61  ASN A C   1 
ATOM   412   O O   . ASN A 1 61  ? 123.912 142.006 143.363 1.00 36.58  ? 61  ASN A O   1 
ATOM   413   C CB  . ASN A 1 61  ? 124.587 139.159 143.381 1.00 36.58  ? 61  ASN A CB  1 
ATOM   414   C CG  . ASN A 1 61  ? 124.602 137.654 143.458 1.00 36.58  ? 61  ASN A CG  1 
ATOM   415   O OD1 . ASN A 1 61  ? 123.642 137.037 143.914 1.00 36.58  ? 61  ASN A OD1 1 
ATOM   416   N ND2 . ASN A 1 61  ? 125.697 137.049 143.016 1.00 36.58  ? 61  ASN A ND2 1 
ATOM   417   N N   . ILE A 1 62  ? 122.286 141.442 144.814 1.00 47.29  ? 62  ILE A N   1 
ATOM   418   C CA  . ILE A 1 62  ? 122.001 142.807 145.236 1.00 47.29  ? 62  ILE A CA  1 
ATOM   419   C C   . ILE A 1 62  ? 122.472 143.007 146.668 1.00 47.29  ? 62  ILE A C   1 
ATOM   420   O O   . ILE A 1 62  ? 122.416 142.084 147.488 1.00 47.29  ? 62  ILE A O   1 
ATOM   421   C CB  . ILE A 1 62  ? 120.501 143.125 145.091 1.00 47.29  ? 62  ILE A CB  1 
ATOM   422   C CG1 . ILE A 1 62  ? 119.687 142.427 146.174 1.00 47.29  ? 62  ILE A CG1 1 
ATOM   423   C CG2 . ILE A 1 62  ? 120.001 142.677 143.738 1.00 47.29  ? 62  ILE A CG2 1 
ATOM   424   C CD1 . ILE A 1 62  ? 118.206 142.643 146.042 1.00 47.29  ? 62  ILE A CD1 1 
ATOM   425   N N   . PHE A 1 63  ? 122.981 144.205 146.957 1.00 43.55  ? 63  PHE A N   1 
ATOM   426   C CA  . PHE A 1 63  ? 123.282 144.611 148.328 1.00 43.55  ? 63  PHE A CA  1 
ATOM   427   C C   . PHE A 1 63  ? 122.163 145.521 148.829 1.00 43.55  ? 63  PHE A C   1 
ATOM   428   O O   . PHE A 1 63  ? 122.302 146.739 148.918 1.00 43.55  ? 63  PHE A O   1 
ATOM   429   C CB  . PHE A 1 63  ? 124.649 145.277 148.428 1.00 43.55  ? 63  PHE A CB  1 
ATOM   430   C CG  . PHE A 1 63  ? 125.793 144.312 148.360 1.00 43.55  ? 63  PHE A CG  1 
ATOM   431   C CD1 . PHE A 1 63  ? 125.569 142.956 148.482 1.00 43.55  ? 63  PHE A CD1 1 
ATOM   432   C CD2 . PHE A 1 63  ? 127.092 144.758 148.215 1.00 43.55  ? 63  PHE A CD2 1 
ATOM   433   C CE1 . PHE A 1 63  ? 126.613 142.063 148.432 1.00 43.55  ? 63  PHE A CE1 1 
ATOM   434   C CE2 . PHE A 1 63  ? 128.141 143.867 148.166 1.00 43.55  ? 63  PHE A CE2 1 
ATOM   435   C CZ  . PHE A 1 63  ? 127.900 142.518 148.275 1.00 43.55  ? 63  PHE A CZ  1 
ATOM   436   N N   . LEU A 1 64  ? 121.037 144.903 149.175 1.00 42.15  ? 64  LEU A N   1 
ATOM   437   C CA  . LEU A 1 64  ? 119.858 145.663 149.566 1.00 42.15  ? 64  LEU A CA  1 
ATOM   438   C C   . LEU A 1 64  ? 120.039 146.244 150.961 1.00 42.15  ? 64  LEU A C   1 
ATOM   439   O O   . LEU A 1 64  ? 120.308 145.514 151.919 1.00 42.15  ? 64  LEU A O   1 
ATOM   440   C CB  . LEU A 1 64  ? 118.617 144.771 149.497 1.00 42.15  ? 64  LEU A CB  1 
ATOM   441   C CG  . LEU A 1 64  ? 117.300 145.138 150.183 1.00 42.15  ? 64  LEU A CG  1 
ATOM   442   C CD1 . LEU A 1 64  ? 116.172 144.465 149.437 1.00 42.15  ? 64  LEU A CD1 1 
ATOM   443   C CD2 . LEU A 1 64  ? 117.260 144.685 151.630 1.00 42.15  ? 64  LEU A CD2 1 
ATOM   444   N N   . ARG A 1 65  ? 119.880 147.558 151.081 1.00 47.29  ? 65  ARG A N   1 
ATOM   445   C CA  . ARG A 1 65  ? 120.066 148.258 152.342 1.00 47.29  ? 65  ARG A CA  1 
ATOM   446   C C   . ARG A 1 65  ? 118.808 149.037 152.686 1.00 47.29  ? 65  ARG A C   1 
ATOM   447   O O   . ARG A 1 65  ? 118.207 149.673 151.817 1.00 47.29  ? 65  ARG A O   1 
ATOM   448   C CB  . ARG A 1 65  ? 121.259 149.211 152.278 1.00 47.29  ? 65  ARG A CB  1 
ATOM   449   C CG  . ARG A 1 65  ? 122.498 148.600 151.664 1.00 47.29  ? 65  ARG A CG  1 
ATOM   450   C CD  . ARG A 1 65  ? 123.699 149.504 151.836 1.00 47.29  ? 65  ARG A CD  1 
ATOM   451   N NE  . ARG A 1 65  ? 124.828 149.054 151.033 1.00 47.29  ? 65  ARG A NE  1 
ATOM   452   C CZ  . ARG A 1 65  ? 125.140 149.545 149.842 1.00 47.29  ? 65  ARG A CZ  1 
ATOM   453   N NH1 . ARG A 1 65  ? 124.438 150.521 149.292 1.00 47.29  ? 65  ARG A NH1 1 
ATOM   454   N NH2 . ARG A 1 65  ? 126.184 149.046 149.189 1.00 47.29  ? 65  ARG A NH2 1 
ATOM   455   N N   . GLN A 1 66  ? 118.420 148.991 153.956 1.00 33.18  ? 66  GLN A N   1 
ATOM   456   C CA  . GLN A 1 66  ? 117.220 149.658 154.436 1.00 33.18  ? 66  GLN A CA  1 
ATOM   457   C C   . GLN A 1 66  ? 117.563 150.537 155.626 1.00 33.18  ? 66  GLN A C   1 
ATOM   458   O O   . GLN A 1 66  ? 118.353 150.146 156.489 1.00 33.18  ? 66  GLN A O   1 
ATOM   459   C CB  . GLN A 1 66  ? 116.147 148.648 154.840 1.00 33.18  ? 66  GLN A CB  1 
ATOM   460   C CG  . GLN A 1 66  ? 116.010 147.477 153.894 1.00 33.18  ? 66  GLN A CG  1 
ATOM   461   C CD  . GLN A 1 66  ? 115.034 146.443 154.400 1.00 33.18  ? 66  GLN A CD  1 
ATOM   462   O OE1 . GLN A 1 66  ? 113.857 146.732 154.600 1.00 33.18  ? 66  GLN A OE1 1 
ATOM   463   N NE2 . GLN A 1 66  ? 115.518 145.227 154.611 1.00 33.18  ? 66  GLN A NE2 1 
ATOM   464   N N   . LYS A 1 67  ? 116.965 151.722 155.671 1.00 33.70  ? 67  LYS A N   1 
ATOM   465   C CA  . LYS A 1 67  ? 117.142 152.649 156.778 1.00 33.70  ? 67  LYS A CA  1 
ATOM   466   C C   . LYS A 1 67  ? 115.779 153.063 157.309 1.00 33.70  ? 67  LYS A C   1 
ATOM   467   O O   . LYS A 1 67  ? 114.866 153.357 156.533 1.00 33.70  ? 67  LYS A O   1 
ATOM   468   C CB  . LYS A 1 67  ? 117.930 153.890 156.350 1.00 33.70  ? 67  LYS A CB  1 
ATOM   469   C CG  . LYS A 1 67  ? 119.116 153.597 155.449 1.00 33.70  ? 67  LYS A CG  1 
ATOM   470   C CD  . LYS A 1 67  ? 119.887 154.865 155.125 1.00 33.70  ? 67  LYS A CD  1 
ATOM   471   C CE  . LYS A 1 67  ? 120.989 154.599 154.113 1.00 33.70  ? 67  LYS A CE  1 
ATOM   472   N NZ  . LYS A 1 67  ? 120.449 154.220 152.779 1.00 33.70  ? 67  LYS A NZ  1 
ATOM   473   N N   . TRP A 1 68  ? 115.645 153.087 158.632 1.00 32.51  ? 68  TRP A N   1 
ATOM   474   C CA  . TRP A 1 68  ? 114.395 153.496 159.255 1.00 32.51  ? 68  TRP A CA  1 
ATOM   475   C C   . TRP A 1 68  ? 114.686 153.975 160.667 1.00 32.51  ? 68  TRP A C   1 
ATOM   476   O O   . TRP A 1 68  ? 115.749 153.701 161.227 1.00 32.51  ? 68  TRP A O   1 
ATOM   477   C CB  . TRP A 1 68  ? 113.370 152.357 159.271 1.00 32.51  ? 68  TRP A CB  1 
ATOM   478   C CG  . TRP A 1 68  ? 113.722 151.221 160.180 1.00 32.51  ? 68  TRP A CG  1 
ATOM   479   C CD1 . TRP A 1 68  ? 113.418 151.108 161.502 1.00 32.51  ? 68  TRP A CD1 1 
ATOM   480   C CD2 . TRP A 1 68  ? 114.430 150.028 159.829 1.00 32.51  ? 68  TRP A CD2 1 
ATOM   481   N NE1 . TRP A 1 68  ? 113.899 149.924 162.000 1.00 32.51  ? 68  TRP A NE1 1 
ATOM   482   C CE2 . TRP A 1 68  ? 114.525 149.242 160.991 1.00 32.51  ? 68  TRP A CE2 1 
ATOM   483   C CE3 . TRP A 1 68  ? 114.996 149.551 158.646 1.00 32.51  ? 68  TRP A CE3 1 
ATOM   484   C CZ2 . TRP A 1 68  ? 115.163 148.008 161.005 1.00 32.51  ? 68  TRP A CZ2 1 
ATOM   485   C CZ3 . TRP A 1 68  ? 115.628 148.327 158.662 1.00 32.51  ? 68  TRP A CZ3 1 
ATOM   486   C CH2 . TRP A 1 68  ? 115.708 147.569 159.833 1.00 32.51  ? 68  TRP A CH2 1 
ATOM   487   N N   . ASN A 1 69  ? 113.730 154.699 161.232 1.00 38.56  ? 69  ASN A N   1 
ATOM   488   C CA  . ASN A 1 69  ? 113.870 155.213 162.583 1.00 38.56  ? 69  ASN A CA  1 
ATOM   489   C C   . ASN A 1 69  ? 113.293 154.224 163.589 1.00 38.56  ? 69  ASN A C   1 
ATOM   490   O O   . ASN A 1 69  ? 112.465 153.374 163.259 1.00 38.56  ? 69  ASN A O   1 
ATOM   491   C CB  . ASN A 1 69  ? 113.178 156.570 162.717 1.00 38.56  ? 69  ASN A CB  1 
ATOM   492   C CG  . ASN A 1 69  ? 113.581 157.307 163.978 1.00 38.56  ? 69  ASN A CG  1 
ATOM   493   O OD1 . ASN A 1 69  ? 114.531 156.921 164.657 1.00 38.56  ? 69  ASN A OD1 1 
ATOM   494   N ND2 . ASN A 1 69  ? 112.862 158.376 164.295 1.00 38.56  ? 69  ASN A ND2 1 
ATOM   495   N N   . ASP A 1 70  ? 113.750 154.345 164.834 1.00 44.14  ? 70  ASP A N   1 
ATOM   496   C CA  . ASP A 1 70  ? 113.274 153.490 165.921 1.00 44.14  ? 70  ASP A CA  1 
ATOM   497   C C   . ASP A 1 70  ? 113.482 154.232 167.228 1.00 44.14  ? 70  ASP A C   1 
ATOM   498   O O   . ASP A 1 70  ? 114.545 154.134 167.855 1.00 44.14  ? 70  ASP A O   1 
ATOM   499   C CB  . ASP A 1 70  ? 113.992 152.143 165.936 1.00 44.14  ? 70  ASP A CB  1 
ATOM   500   C CG  . ASP A 1 70  ? 113.208 151.075 166.665 1.00 44.14  ? 70  ASP A CG  1 
ATOM   501   O OD1 . ASP A 1 70  ? 112.504 151.413 167.638 1.00 44.14  ? 70  ASP A OD1 1 
ATOM   502   O OD2 . ASP A 1 70  ? 113.291 149.896 166.262 1.00 44.14  ? 70  ASP A OD2 1 
ATOM   503   N N   . PRO A 1 71  ? 112.479 154.989 167.677 1.00 47.97  ? 71  PRO A N   1 
ATOM   504   C CA  . PRO A 1 71  ? 112.682 155.865 168.842 1.00 47.97  ? 71  PRO A CA  1 
ATOM   505   C C   . PRO A 1 71  ? 113.073 155.131 170.111 1.00 47.97  ? 71  PRO A C   1 
ATOM   506   O O   . PRO A 1 71  ? 113.832 155.679 170.919 1.00 47.97  ? 71  PRO A O   1 
ATOM   507   C CB  . PRO A 1 71  ? 111.322 156.562 168.992 1.00 47.97  ? 71  PRO A CB  1 
ATOM   508   C CG  . PRO A 1 71  ? 110.352 155.651 168.318 1.00 47.97  ? 71  PRO A CG  1 
ATOM   509   C CD  . PRO A 1 71  ? 111.099 155.051 167.170 1.00 47.97  ? 71  PRO A CD  1 
ATOM   510   N N   . ARG A 1 72  ? 112.585 153.911 170.316 1.00 46.67  ? 72  ARG A N   1 
ATOM   511   C CA  . ARG A 1 72  ? 112.877 153.167 171.534 1.00 46.67  ? 72  ARG A CA  1 
ATOM   512   C C   . ARG A 1 72  ? 114.201 152.426 171.472 1.00 46.67  ? 72  ARG A C   1 
ATOM   513   O O   . ARG A 1 72  ? 114.437 151.532 172.292 1.00 46.67  ? 72  ARG A O   1 
ATOM   514   C CB  . ARG A 1 72  ? 111.747 152.180 171.829 1.00 46.67  ? 72  ARG A CB  1 
ATOM   515   C CG  . ARG A 1 72  ? 111.480 151.216 170.699 1.00 46.67  ? 72  ARG A CG  1 
ATOM   516   C CD  . ARG A 1 72  ? 110.284 150.344 170.998 1.00 46.67  ? 72  ARG A CD  1 
ATOM   517   N NE  . ARG A 1 72  ? 109.899 149.556 169.837 1.00 46.67  ? 72  ARG A NE  1 
ATOM   518   C CZ  . ARG A 1 72  ? 108.957 148.624 169.846 1.00 46.67  ? 72  ARG A CZ  1 
ATOM   519   N NH1 . ARG A 1 72  ? 108.288 148.330 170.948 1.00 46.67  ? 72  ARG A NH1 1 
ATOM   520   N NH2 . ARG A 1 72  ? 108.680 147.972 168.722 1.00 46.67  ? 72  ARG A NH2 1 
ATOM   521   N N   . LEU A 1 73  ? 115.067 152.775 170.524 1.00 43.65  ? 73  LEU A N   1 
ATOM   522   C CA  . LEU A 1 73  ? 116.345 152.107 170.361 1.00 43.65  ? 73  LEU A CA  1 
ATOM   523   C C   . LEU A 1 73  ? 117.528 153.065 170.398 1.00 43.65  ? 73  LEU A C   1 
ATOM   524   O O   . LEU A 1 73  ? 118.675 152.606 170.387 1.00 43.65  ? 73  LEU A O   1 
ATOM   525   C CB  . LEU A 1 73  ? 116.355 151.314 169.043 1.00 43.65  ? 73  LEU A CB  1 
ATOM   526   C CG  . LEU A 1 73  ? 117.488 150.339 168.736 1.00 43.65  ? 73  LEU A CG  1 
ATOM   527   C CD1 . LEU A 1 73  ? 116.933 148.956 168.458 1.00 43.65  ? 73  LEU A CD1 1 
ATOM   528   C CD2 . LEU A 1 73  ? 118.279 150.842 167.555 1.00 43.65  ? 73  LEU A CD2 1 
ATOM   529   N N   . ALA A 1 74  ? 117.286 154.370 170.459 1.00 50.08  ? 74  ALA A N   1 
ATOM   530   C CA  . ALA A 1 74  ? 118.369 155.334 170.573 1.00 50.08  ? 74  ALA A CA  1 
ATOM   531   C C   . ALA A 1 74  ? 119.087 155.179 171.908 1.00 50.08  ? 74  ALA A C   1 
ATOM   532   O O   . ALA A 1 74  ? 118.500 154.770 172.912 1.00 50.08  ? 74  ALA A O   1 
ATOM   533   C CB  . ALA A 1 74  ? 117.835 156.758 170.429 1.00 50.08  ? 74  ALA A CB  1 
ATOM   534   N N   . TYR A 1 75  ? 120.374 155.514 171.911 1.00 59.14  ? 75  TYR A N   1 
ATOM   535   C CA  . TYR A 1 75  ? 121.214 155.366 173.088 1.00 59.14  ? 75  TYR A CA  1 
ATOM   536   C C   . TYR A 1 75  ? 122.015 156.640 173.310 1.00 59.14  ? 75  TYR A C   1 
ATOM   537   O O   . TYR A 1 75  ? 122.230 157.434 172.391 1.00 59.14  ? 75  TYR A O   1 
ATOM   538   C CB  . TYR A 1 75  ? 122.163 154.169 172.954 1.00 59.14  ? 75  TYR A CB  1 
ATOM   539   C CG  . TYR A 1 75  ? 123.135 154.287 171.803 1.00 59.14  ? 75  TYR A CG  1 
ATOM   540   C CD1 . TYR A 1 75  ? 122.782 153.875 170.527 1.00 59.14  ? 75  TYR A CD1 1 
ATOM   541   C CD2 . TYR A 1 75  ? 124.407 154.807 171.994 1.00 59.14  ? 75  TYR A CD2 1 
ATOM   542   C CE1 . TYR A 1 75  ? 123.666 153.981 169.475 1.00 59.14  ? 75  TYR A CE1 1 
ATOM   543   C CE2 . TYR A 1 75  ? 125.297 154.916 170.947 1.00 59.14  ? 75  TYR A CE2 1 
ATOM   544   C CZ  . TYR A 1 75  ? 124.922 154.501 169.691 1.00 59.14  ? 75  TYR A CZ  1 
ATOM   545   O OH  . TYR A 1 75  ? 125.807 154.608 168.645 1.00 59.14  ? 75  TYR A OH  1 
ATOM   546   N N   . SER A 1 76  ? 122.456 156.828 174.553 1.00 69.16  ? 76  SER A N   1 
ATOM   547   C CA  . SER A 1 76  ? 123.271 157.976 174.916 1.00 69.16  ? 76  SER A CA  1 
ATOM   548   C C   . SER A 1 76  ? 124.489 157.628 175.758 1.00 69.16  ? 76  SER A C   1 
ATOM   549   O O   . SER A 1 76  ? 125.287 158.526 176.047 1.00 69.16  ? 76  SER A O   1 
ATOM   550   C CB  . SER A 1 76  ? 122.430 159.015 175.672 1.00 69.16  ? 76  SER A CB  1 
ATOM   551   O OG  . SER A 1 76  ? 121.807 158.435 176.805 1.00 69.16  ? 76  SER A OG  1 
ATOM   552   N N   . GLU A 1 77  ? 124.658 156.367 176.164 1.00 75.44  ? 77  GLU A N   1 
ATOM   553   C CA  . GLU A 1 77  ? 125.791 156.007 177.010 1.00 75.44  ? 77  GLU A CA  1 
ATOM   554   C C   . GLU A 1 77  ? 127.113 156.133 176.261 1.00 75.44  ? 77  GLU A C   1 
ATOM   555   O O   . GLU A 1 77  ? 128.091 156.660 176.803 1.00 75.44  ? 77  GLU A O   1 
ATOM   556   C CB  . GLU A 1 77  ? 125.613 154.587 177.546 1.00 75.44  ? 77  GLU A CB  1 
ATOM   557   N N   . TYR A 1 78  ? 127.165 155.659 175.018 1.00 73.67  ? 78  TYR A N   1 
ATOM   558   C CA  . TYR A 1 78  ? 128.404 155.675 174.251 1.00 73.67  ? 78  TYR A CA  1 
ATOM   559   C C   . TYR A 1 78  ? 128.480 156.940 173.408 1.00 73.67  ? 78  TYR A C   1 
ATOM   560   O O   . TYR A 1 78  ? 127.547 157.215 172.641 1.00 73.67  ? 78  TYR A O   1 
ATOM   561   C CB  . TYR A 1 78  ? 128.503 154.449 173.362 1.00 73.67  ? 78  TYR A CB  1 
ATOM   562   C CG  . TYR A 1 78  ? 129.029 153.230 174.081 1.00 73.67  ? 78  TYR A CG  1 
ATOM   563   C CD1 . TYR A 1 78  ? 129.608 153.341 175.337 1.00 73.67  ? 78  TYR A CD1 1 
ATOM   564   C CD2 . TYR A 1 78  ? 128.953 151.971 173.504 1.00 73.67  ? 78  TYR A CD2 1 
ATOM   565   C CE1 . TYR A 1 78  ? 130.092 152.233 176.001 1.00 73.67  ? 78  TYR A CE1 1 
ATOM   566   C CE2 . TYR A 1 78  ? 129.435 150.856 174.161 1.00 73.67  ? 78  TYR A CE2 1 
ATOM   567   C CZ  . TYR A 1 78  ? 130.004 150.993 175.409 1.00 73.67  ? 78  TYR A CZ  1 
ATOM   568   O OH  . TYR A 1 78  ? 130.487 149.888 176.070 1.00 73.67  ? 78  TYR A OH  1 
ATOM   569   N N   . PRO A 1 79  ? 129.547 157.734 173.521 1.00 81.63  ? 79  PRO A N   1 
ATOM   570   C CA  . PRO A 1 79  ? 129.641 158.955 172.704 1.00 81.63  ? 79  PRO A CA  1 
ATOM   571   C C   . PRO A 1 79  ? 129.682 158.689 171.211 1.00 81.63  ? 79  PRO A C   1 
ATOM   572   O O   . PRO A 1 79  ? 129.268 159.552 170.427 1.00 81.63  ? 79  PRO A O   1 
ATOM   573   C CB  . PRO A 1 79  ? 130.942 159.603 173.197 1.00 81.63  ? 79  PRO A CB  1 
ATOM   574   C CG  . PRO A 1 79  ? 131.744 158.465 173.741 1.00 81.63  ? 79  PRO A CG  1 
ATOM   575   C CD  . PRO A 1 79  ? 130.749 157.517 174.342 1.00 81.63  ? 79  PRO A CD  1 
ATOM   576   N N   . ASP A 1 80  ? 130.176 157.527 170.792 1.00 76.36  ? 80  ASP A N   1 
ATOM   577   C CA  . ASP A 1 80  ? 130.244 157.211 169.372 1.00 76.36  ? 80  ASP A CA  1 
ATOM   578   C C   . ASP A 1 80  ? 128.843 157.108 168.785 1.00 76.36  ? 80  ASP A C   1 
ATOM   579   O O   . ASP A 1 80  ? 127.916 156.612 169.431 1.00 76.36  ? 80  ASP A O   1 
ATOM   580   C CB  . ASP A 1 80  ? 131.006 155.906 169.156 1.00 76.36  ? 80  ASP A CB  1 
ATOM   581   C CG  . ASP A 1 80  ? 131.533 155.768 167.745 1.00 76.36  ? 80  ASP A CG  1 
ATOM   582   O OD1 . ASP A 1 80  ? 131.370 156.721 166.954 1.00 76.36  ? 80  ASP A OD1 1 
ATOM   583   O OD2 . ASP A 1 80  ? 132.113 154.709 167.427 1.00 76.36  ? 80  ASP A OD2 1 
ATOM   584   N N   . ASP A 1 81  ? 128.689 157.584 167.550 1.00 65.91  ? 81  ASP A N   1 
ATOM   585   C CA  . ASP A 1 81  ? 127.376 157.621 166.913 1.00 65.91  ? 81  ASP A CA  1 
ATOM   586   C C   . ASP A 1 81  ? 127.114 156.374 166.070 1.00 65.91  ? 81  ASP A C   1 
ATOM   587   O O   . ASP A 1 81  ? 126.162 155.632 166.329 1.00 65.91  ? 81  ASP A O   1 
ATOM   588   C CB  . ASP A 1 81  ? 127.243 158.887 166.059 1.00 65.91  ? 81  ASP A CB  1 
ATOM   589   C CG  . ASP A 1 81  ? 128.474 159.155 165.222 1.00 65.91  ? 81  ASP A CG  1 
ATOM   590   O OD1 . ASP A 1 81  ? 129.454 158.391 165.346 1.00 65.91  ? 81  ASP A OD1 1 
ATOM   591   O OD2 . ASP A 1 81  ? 128.460 160.127 164.439 1.00 65.91  ? 81  ASP A OD2 1 
ATOM   592   N N   . SER A 1 82  ? 127.953 156.129 165.064 1.00 54.17  ? 82  SER A N   1 
ATOM   593   C CA  . SER A 1 82  ? 127.770 154.988 164.170 1.00 54.17  ? 82  SER A CA  1 
ATOM   594   C C   . SER A 1 82  ? 128.382 153.756 164.829 1.00 54.17  ? 82  SER A C   1 
ATOM   595   O O   . SER A 1 82  ? 129.495 153.324 164.517 1.00 54.17  ? 82  SER A O   1 
ATOM   596   C CB  . SER A 1 82  ? 128.390 155.265 162.808 1.00 54.17  ? 82  SER A CB  1 
ATOM   597   O OG  . SER A 1 82  ? 129.799 155.361 162.902 1.00 54.17  ? 82  SER A OG  1 
ATOM   598   N N   . LEU A 1 83  ? 127.629 153.178 165.760 1.00 45.65  ? 83  LEU A N   1 
ATOM   599   C CA  . LEU A 1 83  ? 128.073 152.001 166.497 1.00 45.65  ? 83  LEU A CA  1 
ATOM   600   C C   . LEU A 1 83  ? 127.702 150.756 165.701 1.00 45.65  ? 83  LEU A C   1 
ATOM   601   O O   . LEU A 1 83  ? 126.519 150.474 165.492 1.00 45.65  ? 83  LEU A O   1 
ATOM   602   C CB  . LEU A 1 83  ? 127.451 151.967 167.888 1.00 45.65  ? 83  LEU A CB  1 
ATOM   603   C CG  . LEU A 1 83  ? 128.084 150.964 168.849 1.00 45.65  ? 83  LEU A CG  1 
ATOM   604   C CD1 . LEU A 1 83  ? 129.521 151.351 169.153 1.00 45.65  ? 83  LEU A CD1 1 
ATOM   605   C CD2 . LEU A 1 83  ? 127.272 150.875 170.123 1.00 45.65  ? 83  LEU A CD2 1 
ATOM   606   N N   . ASP A 1 84  ? 128.712 150.013 165.262 1.00 38.95  ? 84  ASP A N   1 
ATOM   607   C CA  . ASP A 1 84  ? 128.503 148.814 164.464 1.00 38.95  ? 84  ASP A CA  1 
ATOM   608   C C   . ASP A 1 84  ? 128.354 147.607 165.380 1.00 38.95  ? 84  ASP A C   1 
ATOM   609   O O   . ASP A 1 84  ? 129.153 147.417 166.303 1.00 38.95  ? 84  ASP A O   1 
ATOM   610   C CB  . ASP A 1 84  ? 129.667 148.608 163.495 1.00 38.95  ? 84  ASP A CB  1 
ATOM   611   C CG  . ASP A 1 84  ? 129.329 147.651 162.372 1.00 38.95  ? 84  ASP A CG  1 
ATOM   612   O OD1 . ASP A 1 84  ? 128.419 146.814 162.547 1.00 38.95  ? 84  ASP A OD1 1 
ATOM   613   O OD2 . ASP A 1 84  ? 129.975 147.737 161.308 1.00 38.95  ? 84  ASP A OD2 1 
ATOM   614   N N   . LEU A 1 85  ? 127.335 146.795 165.121 1.00 36.92  ? 85  LEU A N   1 
ATOM   615   C CA  . LEU A 1 85  ? 127.072 145.595 165.896 1.00 36.92  ? 85  LEU A CA  1 
ATOM   616   C C   . LEU A 1 85  ? 127.118 144.373 164.990 1.00 36.92  ? 85  LEU A C   1 
ATOM   617   O O   . LEU A 1 85  ? 127.098 144.481 163.761 1.00 36.92  ? 85  LEU A O   1 
ATOM   618   C CB  . LEU A 1 85  ? 125.717 145.673 166.607 1.00 36.92  ? 85  LEU A CB  1 
ATOM   619   C CG  . LEU A 1 85  ? 125.361 147.008 167.258 1.00 36.92  ? 85  LEU A CG  1 
ATOM   620   C CD1 . LEU A 1 85  ? 124.034 146.903 167.974 1.00 36.92  ? 85  LEU A CD1 1 
ATOM   621   C CD2 . LEU A 1 85  ? 126.443 147.440 168.228 1.00 36.92  ? 85  LEU A CD2 1 
ATOM   622   N N   . ASP A 1 86  ? 127.190 143.205 165.614 1.00 40.70  ? 86  ASP A N   1 
ATOM   623   C CA  . ASP A 1 86  ? 127.377 141.973 164.868 1.00 40.70  ? 86  ASP A CA  1 
ATOM   624   C C   . ASP A 1 86  ? 126.069 141.490 164.246 1.00 40.70  ? 86  ASP A C   1 
ATOM   625   O O   . ASP A 1 86  ? 124.988 141.725 164.790 1.00 40.70  ? 86  ASP A O   1 
ATOM   626   C CB  . ASP A 1 86  ? 127.942 140.887 165.771 1.00 40.70  ? 86  ASP A CB  1 
ATOM   627   C CG  . ASP A 1 86  ? 128.949 141.424 166.755 1.00 40.70  ? 86  ASP A CG  1 
ATOM   628   O OD1 . ASP A 1 86  ? 129.726 142.328 166.385 1.00 40.70  ? 86  ASP A OD1 1 
ATOM   629   O OD2 . ASP A 1 86  ? 128.971 140.932 167.896 1.00 40.70  ? 86  ASP A OD2 1 
ATOM   630   N N   . PRO A 1 87  ? 126.153 140.808 163.104 1.00 37.57  ? 87  PRO A N   1 
ATOM   631   C CA  . PRO A 1 87  ? 124.937 140.276 162.471 1.00 37.57  ? 87  PRO A CA  1 
ATOM   632   C C   . PRO A 1 87  ? 124.179 139.284 163.332 1.00 37.57  ? 87  PRO A C   1 
ATOM   633   O O   . PRO A 1 87  ? 122.949 139.205 163.230 1.00 37.57  ? 87  PRO A O   1 
ATOM   634   C CB  . PRO A 1 87  ? 125.471 139.610 161.195 1.00 37.57  ? 87  PRO A CB  1 
ATOM   635   C CG  . PRO A 1 87  ? 126.815 140.208 160.968 1.00 37.57  ? 87  PRO A CG  1 
ATOM   636   C CD  . PRO A 1 87  ? 127.362 140.542 162.309 1.00 37.57  ? 87  PRO A CD  1 
ATOM   637   N N   . SER A 1 88  ? 124.873 138.514 164.172 1.00 43.15  ? 88  SER A N   1 
ATOM   638   C CA  . SER A 1 88  ? 124.215 137.460 164.938 1.00 43.15  ? 88  SER A CA  1 
ATOM   639   C C   . SER A 1 88  ? 123.203 138.009 165.934 1.00 43.15  ? 88  SER A C   1 
ATOM   640   O O   . SER A 1 88  ? 122.317 137.268 166.373 1.00 43.15  ? 88  SER A O   1 
ATOM   641   C CB  . SER A 1 88  ? 125.263 136.617 165.666 1.00 43.15  ? 88  SER A CB  1 
ATOM   642   O OG  . SER A 1 88  ? 126.208 136.085 164.753 1.00 43.15  ? 88  SER A OG  1 
ATOM   643   N N   . MET A 1 89  ? 123.314 139.283 166.300 1.00 41.28  ? 89  MET A N   1 
ATOM   644   C CA  . MET A 1 89  ? 122.388 139.909 167.233 1.00 41.28  ? 89  MET A CA  1 
ATOM   645   C C   . MET A 1 89  ? 121.126 140.421 166.547 1.00 41.28  ? 89  MET A C   1 
ATOM   646   O O   . MET A 1 89  ? 120.160 140.774 167.231 1.00 41.28  ? 89  MET A O   1 
ATOM   647   C CB  . MET A 1 89  ? 123.116 141.045 167.964 1.00 41.28  ? 89  MET A CB  1 
ATOM   648   C CG  . MET A 1 89  ? 122.317 141.804 169.010 1.00 41.28  ? 89  MET A CG  1 
ATOM   649   S SD  . MET A 1 89  ? 121.540 143.276 168.324 1.00 41.28  ? 89  MET A SD  1 
ATOM   650   C CE  . MET A 1 89  ? 122.700 143.676 167.024 1.00 41.28  ? 89  MET A CE  1 
ATOM   651   N N   . LEU A 1 90  ? 121.087 140.406 165.214 1.00 36.52  ? 90  LEU A N   1 
ATOM   652   C CA  . LEU A 1 90  ? 120.006 141.025 164.457 1.00 36.52  ? 90  LEU A CA  1 
ATOM   653   C C   . LEU A 1 90  ? 118.652 140.366 164.682 1.00 36.52  ? 90  LEU A C   1 
ATOM   654   O O   . LEU A 1 90  ? 117.633 140.942 164.289 1.00 36.52  ? 90  LEU A O   1 
ATOM   655   C CB  . LEU A 1 90  ? 120.346 141.001 162.967 1.00 36.52  ? 90  LEU A CB  1 
ATOM   656   C CG  . LEU A 1 90  ? 120.384 142.352 162.261 1.00 36.52  ? 90  LEU A CG  1 
ATOM   657   C CD1 . LEU A 1 90  ? 121.191 142.254 160.985 1.00 36.52  ? 90  LEU A CD1 1 
ATOM   658   C CD2 . LEU A 1 90  ? 118.975 142.813 161.964 1.00 36.52  ? 90  LEU A CD2 1 
ATOM   659   N N   . ASP A 1 91  ? 118.608 139.181 165.289 1.00 42.75  ? 91  ASP A N   1 
ATOM   660   C CA  . ASP A 1 91  ? 117.331 138.530 165.546 1.00 42.75  ? 91  ASP A CA  1 
ATOM   661   C C   . ASP A 1 91  ? 116.561 139.166 166.693 1.00 42.75  ? 91  ASP A C   1 
ATOM   662   O O   . ASP A 1 91  ? 115.383 138.843 166.875 1.00 42.75  ? 91  ASP A O   1 
ATOM   663   C CB  . ASP A 1 91  ? 117.552 137.046 165.836 1.00 42.75  ? 91  ASP A CB  1 
ATOM   664   C CG  . ASP A 1 91  ? 118.360 136.357 164.757 1.00 42.75  ? 91  ASP A CG  1 
ATOM   665   O OD1 . ASP A 1 91  ? 118.365 136.853 163.611 1.00 42.75  ? 91  ASP A OD1 1 
ATOM   666   O OD2 . ASP A 1 91  ? 118.991 135.322 165.054 1.00 42.75  ? 91  ASP A OD2 1 
ATOM   667   N N   . SER A 1 92  ? 117.185 140.052 167.465 1.00 45.27  ? 92  SER A N   1 
ATOM   668   C CA  . SER A 1 92  ? 116.552 140.659 168.627 1.00 45.27  ? 92  SER A CA  1 
ATOM   669   C C   . SER A 1 92  ? 115.999 142.051 168.347 1.00 45.27  ? 92  SER A C   1 
ATOM   670   O O   . SER A 1 92  ? 115.513 142.709 169.272 1.00 45.27  ? 92  SER A O   1 
ATOM   671   C CB  . SER A 1 92  ? 117.541 140.719 169.792 1.00 45.27  ? 92  SER A CB  1 
ATOM   672   O OG  . SER A 1 92  ? 117.954 139.420 170.177 1.00 45.27  ? 92  SER A OG  1 
ATOM   673   N N   . ILE A 1 93  ? 116.057 142.513 167.103 1.00 39.91  ? 93  ILE A N   1 
ATOM   674   C CA  . ILE A 1 93  ? 115.618 143.853 166.736 1.00 39.91  ? 93  ILE A CA  1 
ATOM   675   C C   . ILE A 1 93  ? 114.562 143.737 165.647 1.00 39.91  ? 93  ILE A C   1 
ATOM   676   O O   . ILE A 1 93  ? 114.684 142.910 164.737 1.00 39.91  ? 93  ILE A O   1 
ATOM   677   C CB  . ILE A 1 93  ? 116.801 144.729 166.272 1.00 39.91  ? 93  ILE A CB  1 
ATOM   678   C CG1 . ILE A 1 93  ? 116.309 146.064 165.719 1.00 39.91  ? 93  ILE A CG1 1 
ATOM   679   C CG2 . ILE A 1 93  ? 117.631 144.004 165.234 1.00 39.91  ? 93  ILE A CG2 1 
ATOM   680   C CD1 . ILE A 1 93  ? 117.405 146.903 165.108 1.00 39.91  ? 93  ILE A CD1 1 
ATOM   681   N N   . TRP A 1 94  ? 113.516 144.555 165.753 1.00 40.36  ? 94  TRP A N   1 
ATOM   682   C CA  . TRP A 1 94  ? 112.441 144.527 164.772 1.00 40.36  ? 94  TRP A CA  1 
ATOM   683   C C   . TRP A 1 94  ? 112.970 144.855 163.383 1.00 40.36  ? 94  TRP A C   1 
ATOM   684   O O   . TRP A 1 94  ? 113.833 145.720 163.216 1.00 40.36  ? 94  TRP A O   1 
ATOM   685   C CB  . TRP A 1 94  ? 111.349 145.521 165.155 1.00 40.36  ? 94  TRP A CB  1 
ATOM   686   C CG  . TRP A 1 94  ? 110.182 145.518 164.220 1.00 40.36  ? 94  TRP A CG  1 
ATOM   687   C CD1 . TRP A 1 94  ? 109.111 144.679 164.254 1.00 40.36  ? 94  TRP A CD1 1 
ATOM   688   C CD2 . TRP A 1 94  ? 109.968 146.395 163.109 1.00 40.36  ? 94  TRP A CD2 1 
ATOM   689   N NE1 . TRP A 1 94  ? 108.240 144.979 163.237 1.00 40.36  ? 94  TRP A NE1 1 
ATOM   690   C CE2 . TRP A 1 94  ? 108.744 146.030 162.519 1.00 40.36  ? 94  TRP A CE2 1 
ATOM   691   C CE3 . TRP A 1 94  ? 110.691 147.453 162.556 1.00 40.36  ? 94  TRP A CE3 1 
ATOM   692   C CZ2 . TRP A 1 94  ? 108.228 146.684 161.406 1.00 40.36  ? 94  TRP A CZ2 1 
ATOM   693   C CZ3 . TRP A 1 94  ? 110.175 148.103 161.452 1.00 40.36  ? 94  TRP A CZ3 1 
ATOM   694   C CH2 . TRP A 1 94  ? 108.957 147.716 160.888 1.00 40.36  ? 94  TRP A CH2 1 
ATOM   695   N N   . LYS A 1 95  ? 112.450 144.151 162.382 1.00 35.73  ? 95  LYS A N   1 
ATOM   696   C CA  . LYS A 1 95  ? 112.819 144.380 160.999 1.00 35.73  ? 95  LYS A CA  1 
ATOM   697   C C   . LYS A 1 95  ? 111.561 144.502 160.152 1.00 35.73  ? 95  LYS A C   1 
ATOM   698   O O   . LYS A 1 95  ? 110.565 143.821 160.419 1.00 35.73  ? 95  LYS A O   1 
ATOM   699   C CB  . LYS A 1 95  ? 113.695 143.239 160.468 1.00 35.73  ? 95  LYS A CB  1 
ATOM   700   C CG  . LYS A 1 95  ? 114.967 143.022 161.261 1.00 35.73  ? 95  LYS A CG  1 
ATOM   701   C CD  . LYS A 1 95  ? 115.651 141.728 160.862 1.00 35.73  ? 95  LYS A CD  1 
ATOM   702   C CE  . LYS A 1 95  ? 114.830 140.520 161.273 1.00 35.73  ? 95  LYS A CE  1 
ATOM   703   N NZ  . LYS A 1 95  ? 115.519 139.247 160.931 1.00 35.73  ? 95  LYS A NZ  1 
ATOM   704   N N   . PRO A 1 96  ? 111.569 145.358 159.135 1.00 32.32  ? 96  PRO A N   1 
ATOM   705   C CA  . PRO A 1 96  ? 110.387 145.492 158.282 1.00 32.32  ? 96  PRO A CA  1 
ATOM   706   C C   . PRO A 1 96  ? 110.278 144.337 157.302 1.00 32.32  ? 96  PRO A C   1 
ATOM   707   O O   . PRO A 1 96  ? 111.264 143.911 156.697 1.00 32.32  ? 96  PRO A O   1 
ATOM   708   C CB  . PRO A 1 96  ? 110.629 146.818 157.555 1.00 32.32  ? 96  PRO A CB  1 
ATOM   709   C CG  . PRO A 1 96  ? 112.102 146.934 157.496 1.00 32.32  ? 96  PRO A CG  1 
ATOM   710   C CD  . PRO A 1 96  ? 112.634 146.299 158.754 1.00 32.32  ? 96  PRO A CD  1 
ATOM   711   N N   . ASP A 1 97  ? 109.060 143.827 157.158 1.00 35.12  ? 97  ASP A N   1 
ATOM   712   C CA  . ASP A 1 97  ? 108.804 142.766 156.198 1.00 35.12  ? 97  ASP A CA  1 
ATOM   713   C C   . ASP A 1 97  ? 108.979 143.292 154.781 1.00 35.12  ? 97  ASP A C   1 
ATOM   714   O O   . ASP A 1 97  ? 108.519 144.386 154.446 1.00 35.12  ? 97  ASP A O   1 
ATOM   715   C CB  . ASP A 1 97  ? 107.395 142.211 156.387 1.00 35.12  ? 97  ASP A CB  1 
ATOM   716   C CG  . ASP A 1 97  ? 107.079 141.084 155.430 1.00 35.12  ? 97  ASP A CG  1 
ATOM   717   O OD1 . ASP A 1 97  ? 108.023 140.497 154.863 1.00 35.12  ? 97  ASP A OD1 1 
ATOM   718   O OD2 . ASP A 1 97  ? 105.883 140.786 155.243 1.00 35.12  ? 97  ASP A OD2 1 
ATOM   719   N N   . LEU A 1 98  ? 109.646 142.505 153.943 1.00 32.76  ? 98  LEU A N   1 
ATOM   720   C CA  . LEU A 1 98  ? 109.934 142.913 152.578 1.00 32.76  ? 98  LEU A CA  1 
ATOM   721   C C   . LEU A 1 98  ? 110.136 141.674 151.724 1.00 32.76  ? 98  LEU A C   1 
ATOM   722   O O   . LEU A 1 98  ? 110.770 140.712 152.162 1.00 32.76  ? 98  LEU A O   1 
ATOM   723   C CB  . LEU A 1 98  ? 111.175 143.811 152.521 1.00 32.76  ? 98  LEU A CB  1 
ATOM   724   C CG  . LEU A 1 98  ? 111.729 144.194 151.150 1.00 32.76  ? 98  LEU A CG  1 
ATOM   725   C CD1 . LEU A 1 98  ? 112.134 145.651 151.147 1.00 32.76  ? 98  LEU A CD1 1 
ATOM   726   C CD2 . LEU A 1 98  ? 112.915 143.321 150.790 1.00 32.76  ? 98  LEU A CD2 1 
ATOM   727   N N   . PHE A 1 99  ? 109.598 141.701 150.509 1.00 32.71  ? 99  PHE A N   1 
ATOM   728   C CA  . PHE A 1 99  ? 109.783 140.597 149.580 1.00 32.71  ? 99  PHE A CA  1 
ATOM   729   C C   . PHE A 1 99  ? 109.573 141.114 148.168 1.00 32.71  ? 99  PHE A C   1 
ATOM   730   O O   . PHE A 1 99  ? 109.010 142.191 147.961 1.00 32.71  ? 99  PHE A O   1 
ATOM   731   C CB  . PHE A 1 99  ? 108.833 139.437 149.884 1.00 32.71  ? 99  PHE A CB  1 
ATOM   732   C CG  . PHE A 1 99  ? 107.450 139.623 149.340 1.00 32.71  ? 99  PHE A CG  1 
ATOM   733   C CD1 . PHE A 1 99  ? 106.576 140.517 149.926 1.00 32.71  ? 99  PHE A CD1 1 
ATOM   734   C CD2 . PHE A 1 99  ? 107.020 138.895 148.247 1.00 32.71  ? 99  PHE A CD2 1 
ATOM   735   C CE1 . PHE A 1 99  ? 105.304 140.683 149.430 1.00 32.71  ? 99  PHE A CE1 1 
ATOM   736   C CE2 . PHE A 1 99  ? 105.749 139.060 147.747 1.00 32.71  ? 99  PHE A CE2 1 
ATOM   737   C CZ  . PHE A 1 99  ? 104.891 139.955 148.340 1.00 32.71  ? 99  PHE A CZ  1 
ATOM   738   N N   . PHE A 1 100 ? 110.030 140.330 147.199 1.00 30.58  ? 100 PHE A N   1 
ATOM   739   C CA  . PHE A 1 100 ? 109.989 140.718 145.797 1.00 30.58  ? 100 PHE A CA  1 
ATOM   740   C C   . PHE A 1 100 ? 108.813 140.043 145.106 1.00 30.58  ? 100 PHE A C   1 
ATOM   741   O O   . PHE A 1 100 ? 108.684 138.816 145.146 1.00 30.58  ? 100 PHE A O   1 
ATOM   742   C CB  . PHE A 1 100 ? 111.301 140.358 145.103 1.00 30.58  ? 100 PHE A CB  1 
ATOM   743   C CG  . PHE A 1 100 ? 112.519 140.809 145.852 1.00 30.58  ? 100 PHE A CG  1 
ATOM   744   C CD1 . PHE A 1 100 ? 113.108 139.993 146.795 1.00 30.58  ? 100 PHE A CD1 1 
ATOM   745   C CD2 . PHE A 1 100 ? 113.074 142.050 145.614 1.00 30.58  ? 100 PHE A CD2 1 
ATOM   746   C CE1 . PHE A 1 100 ? 114.223 140.407 147.485 1.00 30.58  ? 100 PHE A CE1 1 
ATOM   747   C CE2 . PHE A 1 100 ? 114.192 142.466 146.304 1.00 30.58  ? 100 PHE A CE2 1 
ATOM   748   C CZ  . PHE A 1 100 ? 114.765 141.645 147.240 1.00 30.58  ? 100 PHE A CZ  1 
ATOM   749   N N   . ALA A 1 101 ? 107.958 140.850 144.475 1.00 29.33  ? 101 ALA A N   1 
ATOM   750   C CA  . ALA A 1 101 ? 106.734 140.319 143.885 1.00 29.33  ? 101 ALA A CA  1 
ATOM   751   C C   . ALA A 1 101 ? 107.031 139.443 142.675 1.00 29.33  ? 101 ALA A C   1 
ATOM   752   O O   . ALA A 1 101 ? 106.480 138.345 142.543 1.00 29.33  ? 101 ALA A O   1 
ATOM   753   C CB  . ALA A 1 101 ? 105.798 141.464 143.503 1.00 29.33  ? 101 ALA A CB  1 
ATOM   754   N N   . ASN A 1 102 ? 107.891 139.911 141.777 1.00 30.93  ? 102 ASN A N   1 
ATOM   755   C CA  . ASN A 1 102 ? 108.220 139.152 140.571 1.00 30.93  ? 102 ASN A CA  1 
ATOM   756   C C   . ASN A 1 102 ? 109.437 138.261 140.789 1.00 30.93  ? 102 ASN A C   1 
ATOM   757   O O   . ASN A 1 102 ? 110.411 138.301 140.041 1.00 30.93  ? 102 ASN A O   1 
ATOM   758   C CB  . ASN A 1 102 ? 108.438 140.101 139.400 1.00 30.93  ? 102 ASN A CB  1 
ATOM   759   C CG  . ASN A 1 102 ? 109.564 141.079 139.644 1.00 30.93  ? 102 ASN A CG  1 
ATOM   760   O OD1 . ASN A 1 102 ? 109.343 142.198 140.099 1.00 30.93  ? 102 ASN A OD1 1 
ATOM   761   N ND2 . ASN A 1 102 ? 110.784 140.658 139.342 1.00 30.93  ? 102 ASN A ND2 1 
ATOM   762   N N   . GLU A 1 103 ? 109.376 137.435 141.826 1.00 31.47  ? 103 GLU A N   1 
ATOM   763   C CA  . GLU A 1 103 ? 110.473 136.561 142.213 1.00 31.47  ? 103 GLU A CA  1 
ATOM   764   C C   . GLU A 1 103 ? 110.073 135.110 141.996 1.00 31.47  ? 103 GLU A C   1 
ATOM   765   O O   . GLU A 1 103 ? 109.026 134.673 142.481 1.00 31.47  ? 103 GLU A O   1 
ATOM   766   C CB  . GLU A 1 103 ? 110.851 136.793 143.675 1.00 31.47  ? 103 GLU A CB  1 
ATOM   767   C CG  . GLU A 1 103 ? 111.592 135.645 144.318 1.00 31.47  ? 103 GLU A CG  1 
ATOM   768   C CD  . GLU A 1 103 ? 111.529 135.702 145.830 1.00 31.47  ? 103 GLU A CD  1 
ATOM   769   O OE1 . GLU A 1 103 ? 110.672 136.438 146.361 1.00 31.47  ? 103 GLU A OE1 1 
ATOM   770   O OE2 . GLU A 1 103 ? 112.321 135.001 146.490 1.00 31.47  ? 103 GLU A OE2 1 
ATOM   771   N N   . LYS A 1 104 ? 110.903 134.370 141.264 1.00 29.89  ? 104 LYS A N   1 
ATOM   772   C CA  . LYS A 1 104 ? 110.682 132.942 141.084 1.00 29.89  ? 104 LYS A CA  1 
ATOM   773   C C   . LYS A 1 104 ? 111.401 132.102 142.125 1.00 29.89  ? 104 LYS A C   1 
ATOM   774   O O   . LYS A 1 104 ? 111.043 130.934 142.315 1.00 29.89  ? 104 LYS A O   1 
ATOM   775   C CB  . LYS A 1 104 ? 111.134 132.499 139.690 1.00 29.89  ? 104 LYS A CB  1 
ATOM   776   C CG  . LYS A 1 104 ? 110.662 133.396 138.564 1.00 29.89  ? 104 LYS A CG  1 
ATOM   777   C CD  . LYS A 1 104 ? 110.099 132.590 137.402 1.00 29.89  ? 104 LYS A CD  1 
ATOM   778   C CE  . LYS A 1 104 ? 110.938 131.357 137.110 1.00 29.89  ? 104 LYS A CE  1 
ATOM   779   N NZ  . LYS A 1 104 ? 112.343 131.703 136.771 1.00 29.89  ? 104 LYS A NZ  1 
ATOM   780   N N   . GLY A 1 105 ? 112.401 132.663 142.794 1.00 28.62  ? 105 GLY A N   1 
ATOM   781   C CA  . GLY A 1 105 ? 113.131 131.950 143.820 1.00 28.62  ? 105 GLY A CA  1 
ATOM   782   C C   . GLY A 1 105 ? 114.355 132.719 144.266 1.00 28.62  ? 105 GLY A C   1 
ATOM   783   O O   . GLY A 1 105 ? 115.074 133.280 143.436 1.00 28.62  ? 105 GLY A O   1 
ATOM   784   N N   . ALA A 1 106 ? 114.603 132.759 145.571 1.00 27.06  ? 106 ALA A N   1 
ATOM   785   C CA  . ALA A 1 106 ? 115.751 133.480 146.095 1.00 27.06  ? 106 ALA A CA  1 
ATOM   786   C C   . ALA A 1 106 ? 116.186 132.844 147.402 1.00 27.06  ? 106 ALA A C   1 
ATOM   787   O O   . ALA A 1 106 ? 115.418 132.137 148.058 1.00 27.06  ? 106 ALA A O   1 
ATOM   788   C CB  . ALA A 1 106 ? 115.441 134.962 146.305 1.00 27.06  ? 106 ALA A CB  1 
ATOM   789   N N   . ASN A 1 107 ? 117.434 133.109 147.776 1.00 28.60  ? 107 ASN A N   1 
ATOM   790   C CA  . ASN A 1 107 ? 117.995 132.549 148.993 1.00 28.60  ? 107 ASN A CA  1 
ATOM   791   C C   . ASN A 1 107 ? 119.041 133.503 149.542 1.00 28.60  ? 107 ASN A C   1 
ATOM   792   O O   . ASN A 1 107 ? 119.623 134.305 148.809 1.00 28.60  ? 107 ASN A O   1 
ATOM   793   C CB  . ASN A 1 107 ? 118.612 131.173 148.739 1.00 28.60  ? 107 ASN A CB  1 
ATOM   794   C CG  . ASN A 1 107 ? 119.478 131.151 147.502 1.00 28.60  ? 107 ASN A CG  1 
ATOM   795   O OD1 . ASN A 1 107 ? 119.142 131.761 146.488 1.00 28.60  ? 107 ASN A OD1 1 
ATOM   796   N ND2 . ASN A 1 107 ? 120.604 130.453 147.578 1.00 28.60  ? 107 ASN A ND2 1 
ATOM   797   N N   . PHE A 1 108 ? 119.277 133.403 150.845 1.00 31.51  ? 108 PHE A N   1 
ATOM   798   C CA  . PHE A 1 108 ? 120.327 134.185 151.471 1.00 31.51  ? 108 PHE A CA  1 
ATOM   799   C C   . PHE A 1 108 ? 121.688 133.608 151.101 1.00 31.51  ? 108 PHE A C   1 
ATOM   800   O O   . PHE A 1 108 ? 121.808 132.673 150.305 1.00 31.51  ? 108 PHE A O   1 
ATOM   801   C CB  . PHE A 1 108 ? 120.153 134.202 152.986 1.00 31.51  ? 108 PHE A CB  1 
ATOM   802   C CG  . PHE A 1 108 ? 118.856 134.789 153.441 1.00 31.51  ? 108 PHE A CG  1 
ATOM   803   C CD1 . PHE A 1 108 ? 118.308 135.876 152.794 1.00 31.51  ? 108 PHE A CD1 1 
ATOM   804   C CD2 . PHE A 1 108 ? 118.189 134.255 154.527 1.00 31.51  ? 108 PHE A CD2 1 
ATOM   805   C CE1 . PHE A 1 108 ? 117.116 136.414 153.215 1.00 31.51  ? 108 PHE A CE1 1 
ATOM   806   C CE2 . PHE A 1 108 ? 116.998 134.791 154.954 1.00 31.51  ? 108 PHE A CE2 1 
ATOM   807   C CZ  . PHE A 1 108 ? 116.462 135.872 154.299 1.00 31.51  ? 108 PHE A CZ  1 
ATOM   808   N N   . HIS A 1 109 ? 122.733 134.175 151.691 1.00 35.44  ? 109 HIS A N   1 
ATOM   809   C CA  . HIS A 1 109 ? 124.084 133.651 151.558 1.00 35.44  ? 109 HIS A CA  1 
ATOM   810   C C   . HIS A 1 109 ? 124.631 133.390 152.952 1.00 35.44  ? 109 HIS A C   1 
ATOM   811   O O   . HIS A 1 109 ? 124.674 134.301 153.784 1.00 35.44  ? 109 HIS A O   1 
ATOM   812   C CB  . HIS A 1 109 ? 124.980 134.620 150.787 1.00 35.44  ? 109 HIS A CB  1 
ATOM   813   C CG  . HIS A 1 109 ? 124.789 134.562 149.304 1.00 35.44  ? 109 HIS A CG  1 
ATOM   814   N ND1 . HIS A 1 109 ? 125.244 133.511 148.538 1.00 35.44  ? 109 HIS A ND1 1 
ATOM   815   C CD2 . HIS A 1 109 ? 124.185 135.418 148.448 1.00 35.44  ? 109 HIS A CD2 1 
ATOM   816   C CE1 . HIS A 1 109 ? 124.933 133.726 147.273 1.00 35.44  ? 109 HIS A CE1 1 
ATOM   817   N NE2 . HIS A 1 109 ? 124.291 134.876 147.191 1.00 35.44  ? 109 HIS A NE2 1 
ATOM   818   N N   . GLU A 1 110 ? 125.042 132.149 153.202 1.00 35.73  ? 110 GLU A N   1 
ATOM   819   C CA  . GLU A 1 110 ? 125.544 131.721 154.505 1.00 35.73  ? 110 GLU A CA  1 
ATOM   820   C C   . GLU A 1 110 ? 126.881 131.029 154.272 1.00 35.73  ? 110 GLU A C   1 
ATOM   821   O O   . GLU A 1 110 ? 126.933 129.812 154.083 1.00 35.73  ? 110 GLU A O   1 
ATOM   822   C CB  . GLU A 1 110 ? 124.547 130.804 155.199 1.00 35.73  ? 110 GLU A CB  1 
ATOM   823   C CG  . GLU A 1 110 ? 123.385 131.530 155.845 1.00 35.73  ? 110 GLU A CG  1 
ATOM   824   C CD  . GLU A 1 110 ? 122.098 130.729 155.798 1.00 35.73  ? 110 GLU A CD  1 
ATOM   825   O OE1 . GLU A 1 110 ? 121.948 129.893 154.883 1.00 35.73  ? 110 GLU A OE1 1 
ATOM   826   O OE2 . GLU A 1 110 ? 121.234 130.939 156.675 1.00 35.73  ? 110 GLU A OE2 1 
ATOM   827   N N   . VAL A 1 111 ? 127.961 131.805 154.277 1.00 31.72  ? 111 VAL A N   1 
ATOM   828   C CA  . VAL A 1 111 ? 129.306 131.283 154.074 1.00 31.72  ? 111 VAL A CA  1 
ATOM   829   C C   . VAL A 1 111 ? 130.179 131.825 155.192 1.00 31.72  ? 111 VAL A C   1 
ATOM   830   O O   . VAL A 1 111 ? 130.444 133.032 155.247 1.00 31.72  ? 111 VAL A O   1 
ATOM   831   C CB  . VAL A 1 111 ? 129.880 131.664 152.706 1.00 31.72  ? 111 VAL A CB  1 
ATOM   832   C CG1 . VAL A 1 111 ? 131.280 131.107 152.556 1.00 31.72  ? 111 VAL A CG1 1 
ATOM   833   C CG2 . VAL A 1 111 ? 128.978 131.169 151.605 1.00 31.72  ? 111 VAL A CG2 1 
ATOM   834   N N   . THR A 1 112 ? 130.594 130.942 156.103 1.00 35.35  ? 112 THR A N   1 
ATOM   835   C CA  . THR A 1 112 ? 131.498 131.228 157.216 1.00 35.35  ? 112 THR A CA  1 
ATOM   836   C C   . THR A 1 112 ? 130.826 132.098 158.271 1.00 35.35  ? 112 THR A C   1 
ATOM   837   O O   . THR A 1 112 ? 131.365 132.275 159.367 1.00 35.35  ? 112 THR A O   1 
ATOM   838   C CB  . THR A 1 112 ? 132.791 131.899 156.737 1.00 35.35  ? 112 THR A CB  1 
ATOM   839   O OG1 . THR A 1 112 ? 132.509 133.237 156.312 1.00 35.35  ? 112 THR A OG1 1 
ATOM   840   C CG2 . THR A 1 112 ? 133.406 131.129 155.582 1.00 35.35  ? 112 THR A CG2 1 
ATOM   841   N N   . THR A 1 113 ? 129.650 132.625 157.953 1.00 36.05  ? 113 THR A N   1 
ATOM   842   C CA  . THR A 1 113 ? 128.840 133.461 158.838 1.00 36.05  ? 113 THR A CA  1 
ATOM   843   C C   . THR A 1 113 ? 127.513 133.708 158.132 1.00 36.05  ? 113 THR A C   1 
ATOM   844   O O   . THR A 1 113 ? 127.243 133.138 157.068 1.00 36.05  ? 113 THR A O   1 
ATOM   845   C CB  . THR A 1 113 ? 129.527 134.785 159.185 1.00 36.05  ? 113 THR A CB  1 
ATOM   846   O OG1 . THR A 1 113 ? 130.637 135.007 158.307 1.00 36.05  ? 113 THR A OG1 1 
ATOM   847   C CG2 . THR A 1 113 ? 130.000 134.786 160.635 1.00 36.05  ? 113 THR A CG2 1 
ATOM   848   N N   . ASP A 1 114 ? 126.685 134.558 158.724 1.00 33.10  ? 114 ASP A N   1 
ATOM   849   C CA  . ASP A 1 114 ? 125.485 135.059 158.074 1.00 33.10  ? 114 ASP A CA  1 
ATOM   850   C C   . ASP A 1 114 ? 125.817 136.388 157.412 1.00 33.10  ? 114 ASP A C   1 
ATOM   851   O O   . ASP A 1 114 ? 126.392 137.276 158.049 1.00 33.10  ? 114 ASP A O   1 
ATOM   852   C CB  . ASP A 1 114 ? 124.345 135.227 159.077 1.00 33.10  ? 114 ASP A CB  1 
ATOM   853   C CG  . ASP A 1 114 ? 122.990 134.926 158.473 1.00 33.10  ? 114 ASP A CG  1 
ATOM   854   O OD1 . ASP A 1 114 ? 122.783 133.782 158.022 1.00 33.10  ? 114 ASP A OD1 1 
ATOM   855   O OD2 . ASP A 1 114 ? 122.131 135.831 158.449 1.00 33.10  ? 114 ASP A OD2 1 
ATOM   856   N N   . ASN A 1 115 ? 125.468 136.518 156.135 1.00 35.87  ? 115 ASN A N   1 
ATOM   857   C CA  . ASN A 1 115 ? 125.800 137.708 155.355 1.00 35.87  ? 115 ASN A CA  1 
ATOM   858   C C   . ASN A 1 115 ? 124.758 138.785 155.622 1.00 35.87  ? 115 ASN A C   1 
ATOM   859   O O   . ASN A 1 115 ? 123.714 138.846 154.973 1.00 35.87  ? 115 ASN A O   1 
ATOM   860   C CB  . ASN A 1 115 ? 125.877 137.372 153.873 1.00 35.87  ? 115 ASN A CB  1 
ATOM   861   C CG  . ASN A 1 115 ? 127.253 136.916 153.454 1.00 35.87  ? 115 ASN A CG  1 
ATOM   862   O OD1 . ASN A 1 115 ? 127.737 137.274 152.382 1.00 35.87  ? 115 ASN A OD1 1 
ATOM   863   N ND2 . ASN A 1 115 ? 127.900 136.131 154.303 1.00 35.87  ? 115 ASN A ND2 1 
ATOM   864   N N   . LYS A 1 116 ? 125.046 139.642 156.597 1.00 33.30  ? 116 LYS A N   1 
ATOM   865   C CA  . LYS A 1 116 ? 124.230 140.820 156.858 1.00 33.30  ? 116 LYS A CA  1 
ATOM   866   C C   . LYS A 1 116 ? 125.046 141.790 157.698 1.00 33.30  ? 116 LYS A C   1 
ATOM   867   O O   . LYS A 1 116 ? 126.125 141.459 158.191 1.00 33.30  ? 116 LYS A O   1 
ATOM   868   C CB  . LYS A 1 116 ? 122.909 140.465 157.544 1.00 33.30  ? 116 LYS A CB  1 
ATOM   869   C CG  . LYS A 1 116 ? 123.025 139.442 158.647 1.00 33.30  ? 116 LYS A CG  1 
ATOM   870   C CD  . LYS A 1 116 ? 121.658 139.068 159.192 1.00 33.30  ? 116 LYS A CD  1 
ATOM   871   C CE  . LYS A 1 116 ? 120.690 138.731 158.072 1.00 33.30  ? 116 LYS A CE  1 
ATOM   872   N NZ  . LYS A 1 116 ? 121.217 137.661 157.182 1.00 33.30  ? 116 LYS A NZ  1 
ATOM   873   N N   . LEU A 1 117 ? 124.522 143.003 157.841 1.00 31.31  ? 117 LEU A N   1 
ATOM   874   C CA  . LEU A 1 117 ? 125.211 144.052 158.576 1.00 31.31  ? 117 LEU A CA  1 
ATOM   875   C C   . LEU A 1 117 ? 124.184 144.972 159.213 1.00 31.31  ? 117 LEU A C   1 
ATOM   876   O O   . LEU A 1 117 ? 123.214 145.368 158.565 1.00 31.31  ? 117 LEU A O   1 
ATOM   877   C CB  . LEU A 1 117 ? 126.140 144.851 157.660 1.00 31.31  ? 117 LEU A CB  1 
ATOM   878   C CG  . LEU A 1 117 ? 126.672 146.184 158.179 1.00 31.31  ? 117 LEU A CG  1 
ATOM   879   C CD1 . LEU A 1 117 ? 128.153 146.301 157.886 1.00 31.31  ? 117 LEU A CD1 1 
ATOM   880   C CD2 . LEU A 1 117 ? 125.922 147.338 157.544 1.00 31.31  ? 117 LEU A CD2 1 
ATOM   881   N N   . LEU A 1 118 ? 124.406 145.313 160.480 1.00 32.71  ? 118 LEU A N   1 
ATOM   882   C CA  . LEU A 1 118 ? 123.517 146.203 161.212 1.00 32.71  ? 118 LEU A CA  1 
ATOM   883   C C   . LEU A 1 118 ? 124.330 147.313 161.856 1.00 32.71  ? 118 LEU A C   1 
ATOM   884   O O   . LEU A 1 118 ? 125.330 147.044 162.528 1.00 32.71  ? 118 LEU A O   1 
ATOM   885   C CB  . LEU A 1 118 ? 122.726 145.444 162.279 1.00 32.71  ? 118 LEU A CB  1 
ATOM   886   C CG  . LEU A 1 118 ? 121.908 146.330 163.218 1.00 32.71  ? 118 LEU A CG  1 
ATOM   887   C CD1 . LEU A 1 118 ? 120.468 145.866 163.282 1.00 32.71  ? 118 LEU A CD1 1 
ATOM   888   C CD2 . LEU A 1 118 ? 122.523 146.349 164.604 1.00 32.71  ? 118 LEU A CD2 1 
ATOM   889   N N   . ARG A 1 119 ? 123.899 148.555 161.651 1.00 33.84  ? 119 ARG A N   1 
ATOM   890   C CA  . ARG A 1 119 ? 124.502 149.717 162.284 1.00 33.84  ? 119 ARG A CA  1 
ATOM   891   C C   . ARG A 1 119 ? 123.409 150.529 162.955 1.00 33.84  ? 119 ARG A C   1 
ATOM   892   O O   . ARG A 1 119 ? 122.278 150.581 162.467 1.00 33.84  ? 119 ARG A O   1 
ATOM   893   C CB  . ARG A 1 119 ? 125.251 150.590 161.275 1.00 33.84  ? 119 ARG A CB  1 
ATOM   894   C CG  . ARG A 1 119 ? 126.297 149.850 160.468 1.00 33.84  ? 119 ARG A CG  1 
ATOM   895   C CD  . ARG A 1 119 ? 126.668 150.626 159.219 1.00 33.84  ? 119 ARG A CD  1 
ATOM   896   N NE  . ARG A 1 119 ? 127.315 151.893 159.532 1.00 33.84  ? 119 ARG A NE  1 
ATOM   897   C CZ  . ARG A 1 119 ? 128.626 152.082 159.518 1.00 33.84  ? 119 ARG A CZ  1 
ATOM   898   N NH1 . ARG A 1 119 ? 129.461 151.103 159.212 1.00 33.84  ? 119 ARG A NH1 1 
ATOM   899   N NH2 . ARG A 1 119 ? 129.112 153.283 159.818 1.00 33.84  ? 119 ARG A NH2 1 
ATOM   900   N N   . ILE A 1 120 ? 123.748 151.160 164.075 1.00 38.65  ? 120 ILE A N   1 
ATOM   901   C CA  . ILE A 1 120 ? 122.795 151.936 164.856 1.00 38.65  ? 120 ILE A CA  1 
ATOM   902   C C   . ILE A 1 120 ? 123.385 153.314 165.113 1.00 38.65  ? 120 ILE A C   1 
ATOM   903   O O   . ILE A 1 120 ? 124.524 153.428 165.580 1.00 38.65  ? 120 ILE A O   1 
ATOM   904   C CB  . ILE A 1 120 ? 122.451 151.238 166.183 1.00 38.65  ? 120 ILE A CB  1 
ATOM   905   C CG1 . ILE A 1 120 ? 121.693 149.941 165.913 1.00 38.65  ? 120 ILE A CG1 1 
ATOM   906   C CG2 . ILE A 1 120 ? 121.638 152.156 167.070 1.00 38.65  ? 120 ILE A CG2 1 
ATOM   907   C CD1 . ILE A 1 120 ? 121.399 149.147 167.153 1.00 38.65  ? 120 ILE A CD1 1 
ATOM   908   N N   . PHE A 1 121 ? 122.616 154.352 164.811 1.00 44.28  ? 121 PHE A N   1 
ATOM   909   C CA  . PHE A 1 121 ? 123.029 155.728 165.036 1.00 44.28  ? 121 PHE A CA  1 
ATOM   910   C C   . PHE A 1 121 ? 122.456 156.244 166.352 1.00 44.28  ? 121 PHE A C   1 
ATOM   911   O O   . PHE A 1 121 ? 121.578 155.632 166.962 1.00 44.28  ? 121 PHE A O   1 
ATOM   912   C CB  . PHE A 1 121 ? 122.590 156.616 163.872 1.00 44.28  ? 121 PHE A CB  1 
ATOM   913   C CG  . PHE A 1 121 ? 123.106 156.164 162.538 1.00 44.28  ? 121 PHE A CG  1 
ATOM   914   C CD1 . PHE A 1 121 ? 124.354 156.558 162.096 1.00 44.28  ? 121 PHE A CD1 1 
ATOM   915   C CD2 . PHE A 1 121 ? 122.343 155.347 161.727 1.00 44.28  ? 121 PHE A CD2 1 
ATOM   916   C CE1 . PHE A 1 121 ? 124.830 156.144 160.869 1.00 44.28  ? 121 PHE A CE1 1 
ATOM   917   C CE2 . PHE A 1 121 ? 122.813 154.931 160.501 1.00 44.28  ? 121 PHE A CE2 1 
ATOM   918   C CZ  . PHE A 1 121 ? 124.058 155.329 160.071 1.00 44.28  ? 121 PHE A CZ  1 
ATOM   919   N N   . LYS A 1 122 ? 122.975 157.393 166.790 1.00 53.91  ? 122 LYS A N   1 
ATOM   920   C CA  . LYS A 1 122 ? 122.532 157.965 168.059 1.00 53.91  ? 122 LYS A CA  1 
ATOM   921   C C   . LYS A 1 122 ? 121.067 158.375 168.008 1.00 53.91  ? 122 LYS A C   1 
ATOM   922   O O   . LYS A 1 122 ? 120.323 158.161 168.971 1.00 53.91  ? 122 LYS A O   1 
ATOM   923   C CB  . LYS A 1 122 ? 123.405 159.161 168.434 1.00 53.91  ? 122 LYS A CB  1 
ATOM   924   C CG  . LYS A 1 122 ? 124.736 158.784 169.054 1.00 53.91  ? 122 LYS A CG  1 
ATOM   925   C CD  . LYS A 1 122 ? 125.404 159.984 169.697 1.00 53.91  ? 122 LYS A CD  1 
ATOM   926   C CE  . LYS A 1 122 ? 124.557 160.540 170.827 1.00 53.91  ? 122 LYS A CE  1 
ATOM   927   N NZ  . LYS A 1 122 ? 124.292 159.514 171.872 1.00 53.91  ? 122 LYS A NZ  1 
ATOM   928   N N   . ASN A 1 123 ? 120.631 158.968 166.896 1.00 49.16  ? 123 ASN A N   1 
ATOM   929   C CA  . ASN A 1 123 ? 119.259 159.448 166.803 1.00 49.16  ? 123 ASN A CA  1 
ATOM   930   C C   . ASN A 1 123 ? 118.240 158.321 166.693 1.00 49.16  ? 123 ASN A C   1 
ATOM   931   O O   . ASN A 1 123 ? 117.039 158.587 166.789 1.00 49.16  ? 123 ASN A O   1 
ATOM   932   C CB  . ASN A 1 123 ? 119.116 160.401 165.614 1.00 49.16  ? 123 ASN A CB  1 
ATOM   933   C CG  . ASN A 1 123 ? 119.695 159.832 164.336 1.00 49.16  ? 123 ASN A CG  1 
ATOM   934   O OD1 . ASN A 1 123 ? 119.373 158.714 163.938 1.00 49.16  ? 123 ASN A OD1 1 
ATOM   935   N ND2 . ASN A 1 123 ? 120.560 160.600 163.686 1.00 49.16  ? 123 ASN A ND2 1 
ATOM   936   N N   . GLY A 1 124 ? 118.682 157.083 166.497 1.00 40.23  ? 124 GLY A N   1 
ATOM   937   C CA  . GLY A 1 124 ? 117.790 155.947 166.393 1.00 40.23  ? 124 GLY A CA  1 
ATOM   938   C C   . GLY A 1 124 ? 117.707 155.333 165.015 1.00 40.23  ? 124 GLY A C   1 
ATOM   939   O O   . GLY A 1 124 ? 117.065 154.287 164.863 1.00 40.23  ? 124 GLY A O   1 
ATOM   940   N N   . ASN A 1 125 ? 118.324 155.942 164.006 1.00 37.69  ? 125 ASN A N   1 
ATOM   941   C CA  . ASN A 1 125 ? 118.309 155.367 162.670 1.00 37.69  ? 125 ASN A CA  1 
ATOM   942   C C   . ASN A 1 125 ? 119.061 154.044 162.656 1.00 37.69  ? 125 ASN A C   1 
ATOM   943   O O   . ASN A 1 125 ? 120.064 153.873 163.354 1.00 37.69  ? 125 ASN A O   1 
ATOM   944   C CB  . ASN A 1 125 ? 118.929 156.335 161.665 1.00 37.69  ? 125 ASN A CB  1 
ATOM   945   C CG  . ASN A 1 125 ? 118.052 157.539 161.400 1.00 37.69  ? 125 ASN A CG  1 
ATOM   946   O OD1 . ASN A 1 125 ? 116.829 157.462 161.501 1.00 37.69  ? 125 ASN A OD1 1 
ATOM   947   N ND2 . ASN A 1 125 ? 118.673 158.661 161.060 1.00 37.69  ? 125 ASN A ND2 1 
ATOM   948   N N   . VAL A 1 126 ? 118.566 153.101 161.860 1.00 33.67  ? 126 VAL A N   1 
ATOM   949   C CA  . VAL A 1 126 ? 119.124 151.759 161.778 1.00 33.67  ? 126 VAL A CA  1 
ATOM   950   C C   . VAL A 1 126 ? 119.385 151.433 160.317 1.00 33.67  ? 126 VAL A C   1 
ATOM   951   O O   . VAL A 1 126 ? 118.526 151.673 159.463 1.00 33.67  ? 126 VAL A O   1 
ATOM   952   C CB  . VAL A 1 126 ? 118.181 150.715 162.404 1.00 33.67  ? 126 VAL A CB  1 
ATOM   953   C CG1 . VAL A 1 126 ? 118.693 149.316 162.149 1.00 33.67  ? 126 VAL A CG1 1 
ATOM   954   C CG2 . VAL A 1 126 ? 118.035 150.964 163.887 1.00 33.67  ? 126 VAL A CG2 1 
ATOM   955   N N   . LEU A 1 127 ? 120.568 150.901 160.028 1.00 31.51  ? 127 LEU A N   1 
ATOM   956   C CA  . LEU A 1 127 ? 120.912 150.403 158.704 1.00 31.51  ? 127 LEU A CA  1 
ATOM   957   C C   . LEU A 1 127 ? 120.971 148.886 158.763 1.00 31.51  ? 127 LEU A C   1 
ATOM   958   O O   . LEU A 1 127 ? 121.573 148.323 159.681 1.00 31.51  ? 127 LEU A O   1 
ATOM   959   C CB  . LEU A 1 127 ? 122.248 150.974 158.228 1.00 31.51  ? 127 LEU A CB  1 
ATOM   960   C CG  . LEU A 1 127 ? 122.540 150.896 156.729 1.00 31.51  ? 127 LEU A CG  1 
ATOM   961   C CD1 . LEU A 1 127 ? 123.359 152.092 156.287 1.00 31.51  ? 127 LEU A CD1 1 
ATOM   962   C CD2 . LEU A 1 127 ? 123.263 149.613 156.385 1.00 31.51  ? 127 LEU A CD2 1 
ATOM   963   N N   . TYR A 1 128 ? 120.347 148.227 157.790 1.00 31.65  ? 128 TYR A N   1 
ATOM   964   C CA  . TYR A 1 128 ? 120.226 146.769 157.795 1.00 31.65  ? 128 TYR A CA  1 
ATOM   965   C C   . TYR A 1 128 ? 120.386 146.274 156.362 1.00 31.65  ? 128 TYR A C   1 
ATOM   966   O O   . TYR A 1 128 ? 119.471 146.414 155.546 1.00 31.65  ? 128 TYR A O   1 
ATOM   967   C CB  . TYR A 1 128 ? 118.893 146.341 158.390 1.00 31.65  ? 128 TYR A CB  1 
ATOM   968   C CG  . TYR A 1 128 ? 118.493 144.926 158.066 1.00 31.65  ? 128 TYR A CG  1 
ATOM   969   C CD1 . TYR A 1 128 ? 119.203 143.853 158.574 1.00 31.65  ? 128 TYR A CD1 1 
ATOM   970   C CD2 . TYR A 1 128 ? 117.395 144.663 157.263 1.00 31.65  ? 128 TYR A CD2 1 
ATOM   971   C CE1 . TYR A 1 128 ? 118.837 142.557 158.287 1.00 31.65  ? 128 TYR A CE1 1 
ATOM   972   C CE2 . TYR A 1 128 ? 117.020 143.371 156.970 1.00 31.65  ? 128 TYR A CE2 1 
ATOM   973   C CZ  . TYR A 1 128 ? 117.744 142.322 157.485 1.00 31.65  ? 128 TYR A CZ  1 
ATOM   974   O OH  . TYR A 1 128 ? 117.375 141.030 157.196 1.00 31.65  ? 128 TYR A OH  1 
ATOM   975   N N   . SER A 1 129 ? 121.544 145.698 156.061 1.00 32.53  ? 129 SER A N   1 
ATOM   976   C CA  . SER A 1 129 ? 121.878 145.242 154.719 1.00 32.53  ? 129 SER A CA  1 
ATOM   977   C C   . SER A 1 129 ? 122.070 143.731 154.736 1.00 32.53  ? 129 SER A C   1 
ATOM   978   O O   . SER A 1 129 ? 122.992 143.233 155.385 1.00 32.53  ? 129 SER A O   1 
ATOM   979   C CB  . SER A 1 129 ? 123.143 145.938 154.224 1.00 32.53  ? 129 SER A CB  1 
ATOM   980   O OG  . SER A 1 129 ? 124.273 145.491 154.949 1.00 32.53  ? 129 SER A OG  1 
ATOM   981   N N   . ILE A 1 130 ? 121.219 143.010 154.006 1.00 36.86  ? 130 ILE A N   1 
ATOM   982   C CA  . ILE A 1 130 ? 121.194 141.550 154.027 1.00 36.86  ? 130 ILE A CA  1 
ATOM   983   C C   . ILE A 1 130 ? 121.289 141.040 152.598 1.00 36.86  ? 130 ILE A C   1 
ATOM   984   O O   . ILE A 1 130 ? 120.521 141.469 151.733 1.00 36.86  ? 130 ILE A O   1 
ATOM   985   C CB  . ILE A 1 130 ? 119.923 141.012 154.710 1.00 36.86  ? 130 ILE A CB  1 
ATOM   986   C CG1 . ILE A 1 130 ? 119.756 139.520 154.431 1.00 36.86  ? 130 ILE A CG1 1 
ATOM   987   C CG2 . ILE A 1 130 ? 118.701 141.779 154.241 1.00 36.86  ? 130 ILE A CG2 1 
ATOM   988   C CD1 . ILE A 1 130 ? 118.540 138.916 155.086 1.00 36.86  ? 130 ILE A CD1 1 
ATOM   989   N N   . ARG A 1 131 ? 122.224 140.125 152.352 1.00 47.29  ? 131 ARG A N   1 
ATOM   990   C CA  . ARG A 1 131 ? 122.569 139.723 150.994 1.00 47.29  ? 131 ARG A CA  1 
ATOM   991   C C   . ARG A 1 131 ? 121.524 138.781 150.419 1.00 47.29  ? 131 ARG A C   1 
ATOM   992   O O   . ARG A 1 131 ? 120.938 137.967 151.136 1.00 47.29  ? 131 ARG A O   1 
ATOM   993   C CB  . ARG A 1 131 ? 123.949 139.067 150.979 1.00 47.29  ? 131 ARG A CB  1 
ATOM   994   C CG  . ARG A 1 131 ? 124.526 138.818 149.600 1.00 47.29  ? 131 ARG A CG  1 
ATOM   995   C CD  . ARG A 1 131 ? 126.029 138.591 149.694 1.00 47.29  ? 131 ARG A CD  1 
ATOM   996   N NE  . ARG A 1 131 ? 126.704 138.800 148.420 1.00 47.29  ? 131 ARG A NE  1 
ATOM   997   C CZ  . ARG A 1 131 ? 127.108 137.825 147.618 1.00 47.29  ? 131 ARG A CZ  1 
ATOM   998   N NH1 . ARG A 1 131 ? 126.957 136.554 147.945 1.00 47.29  ? 131 ARG A NH1 1 
ATOM   999   N NH2 . ARG A 1 131 ? 127.687 138.135 146.462 1.00 47.29  ? 131 ARG A NH2 1 
ATOM   1000  N N   . LEU A 1 132 ? 121.285 138.901 149.117 1.00 47.29  ? 132 LEU A N   1 
ATOM   1001  C CA  . LEU A 1 132 ? 120.288 138.085 148.449 1.00 47.29  ? 132 LEU A CA  1 
ATOM   1002  C C   . LEU A 1 132 ? 120.764 137.739 147.048 1.00 47.29  ? 132 LEU A C   1 
ATOM   1003  O O   . LEU A 1 132 ? 121.631 138.405 146.480 1.00 47.29  ? 132 LEU A O   1 
ATOM   1004  C CB  . LEU A 1 132 ? 118.930 138.792 148.381 1.00 47.29  ? 132 LEU A CB  1 
ATOM   1005  C CG  . LEU A 1 132 ? 118.036 138.672 149.615 1.00 47.29  ? 132 LEU A CG  1 
ATOM   1006  C CD1 . LEU A 1 132 ? 118.248 139.830 150.555 1.00 47.29  ? 132 LEU A CD1 1 
ATOM   1007  C CD2 . LEU A 1 132 ? 116.583 138.588 149.220 1.00 47.29  ? 132 LEU A CD2 1 
ATOM   1008  N N   . THR A 1 133 ? 120.187 136.674 146.501 1.00 29.86  ? 133 THR A N   1 
ATOM   1009  C CA  . THR A 1 133 ? 120.427 136.251 145.125 1.00 29.86  ? 133 THR A CA  1 
ATOM   1010  C C   . THR A 1 133 ? 119.073 135.935 144.508 1.00 29.86  ? 133 THR A C   1 
ATOM   1011  O O   . THR A 1 133 ? 118.480 134.895 144.808 1.00 29.86  ? 133 THR A O   1 
ATOM   1012  C CB  . THR A 1 133 ? 121.355 135.040 145.068 1.00 29.86  ? 133 THR A CB  1 
ATOM   1013  O OG1 . THR A 1 133 ? 122.667 135.425 145.494 1.00 29.86  ? 133 THR A OG1 1 
ATOM   1014  C CG2 . THR A 1 133 ? 121.432 134.491 143.655 1.00 29.86  ? 133 THR A CG2 1 
ATOM   1015  N N   . LEU A 1 134 ? 118.584 136.827 143.656 1.00 27.02  ? 134 LEU A N   1 
ATOM   1016  C CA  . LEU A 1 134 ? 117.225 136.752 143.141 1.00 27.02  ? 134 LEU A CA  1 
ATOM   1017  C C   . LEU A 1 134 ? 117.230 136.220 141.717 1.00 27.02  ? 134 LEU A C   1 
ATOM   1018  O O   . LEU A 1 134 ? 117.943 136.747 140.859 1.00 27.02  ? 134 LEU A O   1 
ATOM   1019  C CB  . LEU A 1 134 ? 116.564 138.126 143.162 1.00 27.02  ? 134 LEU A CB  1 
ATOM   1020  C CG  . LEU A 1 134 ? 116.793 139.027 144.367 1.00 27.02  ? 134 LEU A CG  1 
ATOM   1021  C CD1 . LEU A 1 134 ? 115.920 140.250 144.238 1.00 27.02  ? 134 LEU A CD1 1 
ATOM   1022  C CD2 . LEU A 1 134 ? 116.472 138.290 145.638 1.00 27.02  ? 134 LEU A CD2 1 
ATOM   1023  N N   . THR A 1 135 ? 116.436 135.183 141.468 1.00 25.06  ? 135 THR A N   1 
ATOM   1024  C CA  . THR A 1 135 ? 116.173 134.722 140.107 1.00 25.06  ? 135 THR A CA  1 
ATOM   1025  C C   . THR A 1 135 ? 114.829 135.280 139.645 1.00 25.06  ? 135 THR A C   1 
ATOM   1026  O O   . THR A 1 135 ? 113.852 134.563 139.434 1.00 25.06  ? 135 THR A O   1 
ATOM   1027  C CB  . THR A 1 135 ? 116.209 133.201 140.042 1.00 25.06  ? 135 THR A CB  1 
ATOM   1028  O OG1 . THR A 1 135 ? 117.353 132.721 140.755 1.00 25.06  ? 135 THR A OG1 1 
ATOM   1029  C CG2 . THR A 1 135 ? 116.302 132.737 138.600 1.00 25.06  ? 135 THR A CG2 1 
ATOM   1030  N N   . LEU A 1 136 ? 114.801 136.600 139.496 1.00 27.65  ? 136 LEU A N   1 
ATOM   1031  C CA  . LEU A 1 136 ? 113.572 137.305 139.173 1.00 27.65  ? 136 LEU A CA  1 
ATOM   1032  C C   . LEU A 1 136 ? 113.115 136.977 137.754 1.00 27.65  ? 136 LEU A C   1 
ATOM   1033  O O   . LEU A 1 136 ? 113.839 136.375 136.959 1.00 27.65  ? 136 LEU A O   1 
ATOM   1034  C CB  . LEU A 1 136 ? 113.771 138.808 139.319 1.00 27.65  ? 136 LEU A CB  1 
ATOM   1035  C CG  . LEU A 1 136 ? 114.205 139.269 140.703 1.00 27.65  ? 136 LEU A CG  1 
ATOM   1036  C CD1 . LEU A 1 136 ? 114.714 140.682 140.626 1.00 27.65  ? 136 LEU A CD1 1 
ATOM   1037  C CD2 . LEU A 1 136 ? 113.054 139.170 141.680 1.00 27.65  ? 136 LEU A CD2 1 
ATOM   1038  N N   . SER A 1 137 ? 111.889 137.388 137.440 1.00 29.56  ? 137 SER A N   1 
ATOM   1039  C CA  . SER A 1 137 ? 111.294 137.150 136.134 1.00 29.56  ? 137 SER A CA  1 
ATOM   1040  C C   . SER A 1 137 ? 110.639 138.420 135.618 1.00 29.56  ? 137 SER A C   1 
ATOM   1041  O O   . SER A 1 137 ? 109.965 139.130 136.368 1.00 29.56  ? 137 SER A O   1 
ATOM   1042  C CB  . SER A 1 137 ? 110.256 136.029 136.194 1.00 29.56  ? 137 SER A CB  1 
ATOM   1043  O OG  . SER A 1 137 ? 109.616 135.865 134.942 1.00 29.56  ? 137 SER A OG  1 
ATOM   1044  N N   . CYS A 1 138 ? 110.840 138.698 134.330 1.00 36.60  ? 138 CYS A N   1 
ATOM   1045  C CA  . CYS A 1 138 ? 110.167 139.791 133.651 1.00 36.60  ? 138 CYS A CA  1 
ATOM   1046  C C   . CYS A 1 138 ? 109.704 139.297 132.289 1.00 36.60  ? 138 CYS A C   1 
ATOM   1047  O O   . CYS A 1 138 ? 110.421 138.528 131.632 1.00 36.60  ? 138 CYS A O   1 
ATOM   1048  C CB  . CYS A 1 138 ? 111.076 141.015 133.475 1.00 36.60  ? 138 CYS A CB  1 
ATOM   1049  S SG  . CYS A 1 138 ? 112.532 140.745 132.441 1.00 36.60  ? 138 CYS A SG  1 
ATOM   1050  N N   . PRO A 1 139 ? 108.517 139.706 131.845 1.00 38.96  ? 139 PRO A N   1 
ATOM   1051  C CA  . PRO A 1 139 ? 108.060 139.309 130.509 1.00 38.96  ? 139 PRO A CA  1 
ATOM   1052  C C   . PRO A 1 139 ? 108.980 139.860 129.432 1.00 38.96  ? 139 PRO A C   1 
ATOM   1053  O O   . PRO A 1 139 ? 109.483 140.980 129.531 1.00 38.96  ? 139 PRO A O   1 
ATOM   1054  C CB  . PRO A 1 139 ? 106.656 139.918 130.418 1.00 38.96  ? 139 PRO A CB  1 
ATOM   1055  C CG  . PRO A 1 139 ? 106.250 140.164 131.835 1.00 38.96  ? 139 PRO A CG  1 
ATOM   1056  C CD  . PRO A 1 139 ? 107.512 140.507 132.557 1.00 38.96  ? 139 PRO A CD  1 
ATOM   1057  N N   . MET A 1 140 ? 109.191 139.060 128.393 1.00 45.96  ? 140 MET A N   1 
ATOM   1058  C CA  . MET A 1 140 ? 110.105 139.396 127.313 1.00 45.96  ? 140 MET A CA  1 
ATOM   1059  C C   . MET A 1 140 ? 109.301 139.652 126.047 1.00 45.96  ? 140 MET A C   1 
ATOM   1060  O O   . MET A 1 140 ? 108.456 138.833 125.670 1.00 45.96  ? 140 MET A O   1 
ATOM   1061  C CB  . MET A 1 140 ? 111.109 138.267 127.082 1.00 45.96  ? 140 MET A CB  1 
ATOM   1062  C CG  . MET A 1 140 ? 112.252 138.226 128.083 1.00 45.96  ? 140 MET A CG  1 
ATOM   1063  S SD  . MET A 1 140 ? 113.750 139.074 127.555 1.00 45.96  ? 140 MET A SD  1 
ATOM   1064  C CE  . MET A 1 140 ? 114.658 139.119 129.096 1.00 45.96  ? 140 MET A CE  1 
ATOM   1065  N N   . ASP A 1 141 ? 109.557 140.784 125.397 1.00 50.49  ? 141 ASP A N   1 
ATOM   1066  C CA  . ASP A 1 141 ? 108.883 141.143 124.154 1.00 50.49  ? 141 ASP A CA  1 
ATOM   1067  C C   . ASP A 1 141 ? 109.844 140.883 123.000 1.00 50.49  ? 141 ASP A C   1 
ATOM   1068  O O   . ASP A 1 141 ? 110.841 141.594 122.841 1.00 50.49  ? 141 ASP A O   1 
ATOM   1069  C CB  . ASP A 1 141 ? 108.428 142.600 124.179 1.00 50.49  ? 141 ASP A CB  1 
ATOM   1070  C CG  . ASP A 1 141 ? 107.335 142.886 123.169 1.00 50.49  ? 141 ASP A CG  1 
ATOM   1071  O OD1 . ASP A 1 141 ? 107.480 142.473 122.000 1.00 50.49  ? 141 ASP A OD1 1 
ATOM   1072  O OD2 . ASP A 1 141 ? 106.327 143.520 123.545 1.00 50.49  ? 141 ASP A OD2 1 
ATOM   1073  N N   . LEU A 1 142 ? 109.535 139.875 122.191 1.00 45.40  ? 142 LEU A N   1 
ATOM   1074  C CA  . LEU A 1 142 ? 110.408 139.421 121.115 1.00 45.40  ? 142 LEU A CA  1 
ATOM   1075  C C   . LEU A 1 142 ? 109.832 139.753 119.742 1.00 45.40  ? 142 LEU A C   1 
ATOM   1076  O O   . LEU A 1 142 ? 109.917 138.953 118.810 1.00 45.40  ? 142 LEU A O   1 
ATOM   1077  C CB  . LEU A 1 142 ? 110.669 137.922 121.231 1.00 45.40  ? 142 LEU A CB  1 
ATOM   1078  C CG  . LEU A 1 142 ? 111.140 137.418 122.595 1.00 45.40  ? 142 LEU A CG  1 
ATOM   1079  C CD1 . LEU A 1 142 ? 111.500 135.947 122.526 1.00 45.40  ? 142 LEU A CD1 1 
ATOM   1080  C CD2 . LEU A 1 142 ? 112.320 138.232 123.087 1.00 45.40  ? 142 LEU A CD2 1 
ATOM   1081  N N   . LYS A 1 143 ? 109.230 140.937 119.606 1.00 45.16  ? 143 LYS A N   1 
ATOM   1082  C CA  . LYS A 1 143 ? 108.687 141.339 118.312 1.00 45.16  ? 143 LYS A CA  1 
ATOM   1083  C C   . LYS A 1 143 ? 109.785 141.431 117.262 1.00 45.16  ? 143 LYS A C   1 
ATOM   1084  O O   . LYS A 1 143 ? 109.601 140.994 116.121 1.00 45.16  ? 143 LYS A O   1 
ATOM   1085  C CB  . LYS A 1 143 ? 107.950 142.671 118.441 1.00 45.16  ? 143 LYS A CB  1 
ATOM   1086  N N   . ASN A 1 144 ? 110.932 141.994 117.628 1.00 43.68  ? 144 ASN A N   1 
ATOM   1087  C CA  . ASN A 1 144 ? 112.122 142.020 116.780 1.00 43.68  ? 144 ASN A CA  1 
ATOM   1088  C C   . ASN A 1 144 ? 113.250 141.396 117.595 1.00 43.68  ? 144 ASN A C   1 
ATOM   1089  O O   . ASN A 1 144 ? 114.035 142.100 118.232 1.00 43.68  ? 144 ASN A O   1 
ATOM   1090  C CB  . ASN A 1 144 ? 112.452 143.444 116.332 1.00 43.68  ? 144 ASN A CB  1 
ATOM   1091  C CG  . ASN A 1 144 ? 112.255 144.466 117.434 1.00 43.68  ? 144 ASN A CG  1 
ATOM   1092  O OD1 . ASN A 1 144 ? 113.183 144.786 118.173 1.00 43.68  ? 144 ASN A OD1 1 
ATOM   1093  N ND2 . ASN A 1 144 ? 111.041 144.988 117.544 1.00 43.68  ? 144 ASN A ND2 1 
ATOM   1094  N N   . PHE A 1 145 ? 113.336 140.067 117.551 1.00 43.86  ? 145 PHE A N   1 
ATOM   1095  C CA  . PHE A 1 145 ? 114.162 139.343 118.516 1.00 43.86  ? 145 PHE A CA  1 
ATOM   1096  C C   . PHE A 1 145 ? 115.648 139.668 118.428 1.00 43.86  ? 145 PHE A C   1 
ATOM   1097  O O   . PHE A 1 145 ? 116.235 140.021 119.465 1.00 43.86  ? 145 PHE A O   1 
ATOM   1098  C CB  . PHE A 1 145 ? 113.920 137.838 118.369 1.00 43.86  ? 145 PHE A CB  1 
ATOM   1099  C CG  . PHE A 1 145 ? 115.068 136.993 118.831 1.00 43.86  ? 145 PHE A CG  1 
ATOM   1100  C CD1 . PHE A 1 145 ? 115.346 136.860 120.178 1.00 43.86  ? 145 PHE A CD1 1 
ATOM   1101  C CD2 . PHE A 1 145 ? 115.867 136.332 117.921 1.00 43.86  ? 145 PHE A CD2 1 
ATOM   1102  C CE1 . PHE A 1 145 ? 116.400 136.085 120.605 1.00 43.86  ? 145 PHE A CE1 1 
ATOM   1103  C CE2 . PHE A 1 145 ? 116.921 135.554 118.342 1.00 43.86  ? 145 PHE A CE2 1 
ATOM   1104  C CZ  . PHE A 1 145 ? 117.188 135.430 119.686 1.00 43.86  ? 145 PHE A CZ  1 
ATOM   1105  N N   . PRO A 1 146 ? 116.318 139.570 117.274 1.00 46.97  ? 146 PRO A N   1 
ATOM   1106  C CA  . PRO A 1 146 ? 117.777 139.765 117.272 1.00 46.97  ? 146 PRO A CA  1 
ATOM   1107  C C   . PRO A 1 146 ? 118.211 141.171 117.636 1.00 46.97  ? 146 PRO A C   1 
ATOM   1108  O O   . PRO A 1 146 ? 119.361 141.353 118.052 1.00 46.97  ? 146 PRO A O   1 
ATOM   1109  C CB  . PRO A 1 146 ? 118.181 139.417 115.833 1.00 46.97  ? 146 PRO A CB  1 
ATOM   1110  C CG  . PRO A 1 146 ? 117.030 138.653 115.282 1.00 46.97  ? 146 PRO A CG  1 
ATOM   1111  C CD  . PRO A 1 146 ? 115.828 139.254 115.924 1.00 46.97  ? 146 PRO A CD  1 
ATOM   1112  N N   . MET A 1 147 ? 117.342 142.167 117.495 1.00 49.69  ? 147 MET A N   1 
ATOM   1113  C CA  . MET A 1 147 ? 117.684 143.562 117.757 1.00 49.69  ? 147 MET A CA  1 
ATOM   1114  C C   . MET A 1 147 ? 116.631 144.208 118.648 1.00 49.69  ? 147 MET A C   1 
ATOM   1115  O O   . MET A 1 147 ? 116.149 145.312 118.389 1.00 49.69  ? 147 MET A O   1 
ATOM   1116  C CB  . MET A 1 147 ? 117.843 144.331 116.448 1.00 49.69  ? 147 MET A CB  1 
ATOM   1117  C CG  . MET A 1 147 ? 118.427 143.503 115.311 1.00 49.69  ? 147 MET A CG  1 
ATOM   1118  S SD  . MET A 1 147 ? 118.127 144.200 113.679 1.00 49.69  ? 147 MET A SD  1 
ATOM   1119  C CE  . MET A 1 147 ? 118.503 145.920 113.985 1.00 49.69  ? 147 MET A CE  1 
ATOM   1120  N N   . ASP A 1 148 ? 116.260 143.516 119.720 1.00 45.62  ? 148 ASP A N   1 
ATOM   1121  C CA  . ASP A 1 148 ? 115.225 143.991 120.627 1.00 45.62  ? 148 ASP A CA  1 
ATOM   1122  C C   . ASP A 1 148 ? 115.817 144.843 121.740 1.00 45.62  ? 148 ASP A C   1 
ATOM   1123  O O   . ASP A 1 148 ? 116.989 144.710 122.099 1.00 45.62  ? 148 ASP A O   1 
ATOM   1124  C CB  . ASP A 1 148 ? 114.460 142.818 121.242 1.00 45.62  ? 148 ASP A CB  1 
ATOM   1125  C CG  . ASP A 1 148 ? 115.373 141.817 121.922 1.00 45.62  ? 148 ASP A CG  1 
ATOM   1126  O OD1 . ASP A 1 148 ? 116.601 141.887 121.708 1.00 45.62  ? 148 ASP A OD1 1 
ATOM   1127  O OD2 . ASP A 1 148 ? 114.866 140.960 122.674 1.00 45.62  ? 148 ASP A OD2 1 
ATOM   1128  N N   . VAL A 1 149 ? 114.987 145.729 122.280 1.00 43.96  ? 149 VAL A N   1 
ATOM   1129  C CA  . VAL A 1 149 ? 115.283 146.456 123.508 1.00 43.96  ? 149 VAL A CA  1 
ATOM   1130  C C   . VAL A 1 149 ? 114.261 146.014 124.544 1.00 43.96  ? 149 VAL A C   1 
ATOM   1131  O O   . VAL A 1 149 ? 113.050 146.140 124.325 1.00 43.96  ? 149 VAL A O   1 
ATOM   1132  C CB  . VAL A 1 149 ? 115.250 147.977 123.298 1.00 43.96  ? 149 VAL A CB  1 
ATOM   1133  C CG1 . VAL A 1 149 ? 114.105 148.364 122.378 1.00 43.96  ? 149 VAL A CG1 1 
ATOM   1134  C CG2 . VAL A 1 149 ? 115.127 148.691 124.633 1.00 43.96  ? 149 VAL A CG2 1 
ATOM   1135  N N   . GLN A 1 150 ? 114.742 145.485 125.664 1.00 43.16  ? 150 GLN A N   1 
ATOM   1136  C CA  . GLN A 1 150 ? 113.881 144.848 126.648 1.00 43.16  ? 150 GLN A CA  1 
ATOM   1137  C C   . GLN A 1 150 ? 113.985 145.567 127.982 1.00 43.16  ? 150 GLN A C   1 
ATOM   1138  O O   . GLN A 1 150 ? 115.082 145.915 128.428 1.00 43.16  ? 150 GLN A O   1 
ATOM   1139  C CB  . GLN A 1 150 ? 114.244 143.374 126.820 1.00 43.16  ? 150 GLN A CB  1 
ATOM   1140  C CG  . GLN A 1 150 ? 113.979 142.546 125.581 1.00 43.16  ? 150 GLN A CG  1 
ATOM   1141  C CD  . GLN A 1 150 ? 112.546 142.067 125.490 1.00 43.16  ? 150 GLN A CD  1 
ATOM   1142  O OE1 . GLN A 1 150 ? 112.280 140.869 125.528 1.00 43.16  ? 150 GLN A OE1 1 
ATOM   1143  N NE2 . GLN A 1 150 ? 111.613 143.003 125.355 1.00 43.16  ? 150 GLN A NE2 1 
ATOM   1144  N N   . THR A 1 151 ? 112.839 145.782 128.614 1.00 35.85  ? 151 THR A N   1 
ATOM   1145  C CA  . THR A 1 151 ? 112.763 146.410 129.926 1.00 35.85  ? 151 THR A CA  1 
ATOM   1146  C C   . THR A 1 151 ? 112.446 145.322 130.943 1.00 35.85  ? 151 THR A C   1 
ATOM   1147  O O   . THR A 1 151 ? 111.374 144.710 130.893 1.00 35.85  ? 151 THR A O   1 
ATOM   1148  C CB  . THR A 1 151 ? 111.710 147.513 129.949 1.00 35.85  ? 151 THR A CB  1 
ATOM   1149  O OG1 . THR A 1 151 ? 112.033 148.503 128.965 1.00 35.85  ? 151 THR A OG1 1 
ATOM   1150  C CG2 . THR A 1 151 ? 111.661 148.169 131.316 1.00 35.85  ? 151 THR A CG2 1 
ATOM   1151  N N   . CYS A 1 152 ? 113.379 145.081 131.855 1.00 32.71  ? 152 CYS A N   1 
ATOM   1152  C CA  . CYS A 1 152 ? 113.236 144.068 132.888 1.00 32.71  ? 152 CYS A CA  1 
ATOM   1153  C C   . CYS A 1 152 ? 113.143 144.755 134.243 1.00 32.71  ? 152 CYS A C   1 
ATOM   1154  O O   . CYS A 1 152 ? 113.920 145.667 134.538 1.00 32.71  ? 152 CYS A O   1 
ATOM   1155  C CB  . CYS A 1 152 ? 114.414 143.095 132.856 1.00 32.71  ? 152 CYS A CB  1 
ATOM   1156  S SG  . CYS A 1 152 ? 114.068 141.473 133.550 1.00 32.71  ? 152 CYS A SG  1 
ATOM   1157  N N   . ILE A 1 153 ? 112.193 144.317 135.065 1.00 29.30  ? 153 ILE A N   1 
ATOM   1158  C CA  . ILE A 1 153 ? 111.819 145.054 136.264 1.00 29.30  ? 153 ILE A CA  1 
ATOM   1159  C C   . ILE A 1 153 ? 111.993 144.181 137.494 1.00 29.30  ? 153 ILE A C   1 
ATOM   1160  O O   . ILE A 1 153 ? 111.892 142.952 137.435 1.00 29.30  ? 153 ILE A O   1 
ATOM   1161  C CB  . ILE A 1 153 ? 110.366 145.565 136.180 1.00 29.30  ? 153 ILE A CB  1 
ATOM   1162  C CG1 . ILE A 1 153 ? 109.411 144.402 135.920 1.00 29.30  ? 153 ILE A CG1 1 
ATOM   1163  C CG2 . ILE A 1 153 ? 110.237 146.599 135.086 1.00 29.30  ? 153 ILE A CG2 1 
ATOM   1164  C CD1 . ILE A 1 153 ? 108.071 144.825 135.363 1.00 29.30  ? 153 ILE A CD1 1 
ATOM   1165  N N   . MET A 1 154 ? 112.247 144.838 138.621 1.00 31.25  ? 154 MET A N   1 
ATOM   1166  C CA  . MET A 1 154 ? 112.253 144.204 139.928 1.00 31.25  ? 154 MET A CA  1 
ATOM   1167  C C   . MET A 1 154 ? 111.332 145.001 140.839 1.00 31.25  ? 154 MET A C   1 
ATOM   1168  O O   . MET A 1 154 ? 111.208 146.221 140.706 1.00 31.25  ? 154 MET A O   1 
ATOM   1169  C CB  . MET A 1 154 ? 113.670 144.130 140.515 1.00 31.25  ? 154 MET A CB  1 
ATOM   1170  C CG  . MET A 1 154 ? 113.982 145.209 141.522 1.00 31.25  ? 154 MET A CG  1 
ATOM   1171  S SD  . MET A 1 154 ? 115.735 145.369 141.893 1.00 31.25  ? 154 MET A SD  1 
ATOM   1172  C CE  . MET A 1 154 ? 116.235 143.656 141.950 1.00 31.25  ? 154 MET A CE  1 
ATOM   1173  N N   . GLN A 1 155 ? 110.667 144.303 141.751 1.00 29.35  ? 155 GLN A N   1 
ATOM   1174  C CA  . GLN A 1 155 ? 109.614 144.905 142.553 1.00 29.35  ? 155 GLN A CA  1 
ATOM   1175  C C   . GLN A 1 155 ? 109.872 144.632 144.025 1.00 29.35  ? 155 GLN A C   1 
ATOM   1176  O O   . GLN A 1 155 ? 110.163 143.496 144.405 1.00 29.35  ? 155 GLN A O   1 
ATOM   1177  C CB  . GLN A 1 155 ? 108.245 144.358 142.142 1.00 29.35  ? 155 GLN A CB  1 
ATOM   1178  C CG  . GLN A 1 155 ? 107.180 145.414 141.960 1.00 29.35  ? 155 GLN A CG  1 
ATOM   1179  C CD  . GLN A 1 155 ? 105.986 144.904 141.182 1.00 29.35  ? 155 GLN A CD  1 
ATOM   1180  O OE1 . GLN A 1 155 ? 106.129 144.104 140.258 1.00 29.35  ? 155 GLN A OE1 1 
ATOM   1181  N NE2 . GLN A 1 155 ? 104.799 145.360 141.556 1.00 29.35  ? 155 GLN A NE2 1 
ATOM   1182  N N   . LEU A 1 156 ? 109.767 145.671 144.847 1.00 27.48  ? 156 LEU A N   1 
ATOM   1183  C CA  . LEU A 1 156 ? 109.860 145.547 146.295 1.00 27.48  ? 156 LEU A CA  1 
ATOM   1184  C C   . LEU A 1 156 ? 108.507 145.892 146.895 1.00 27.48  ? 156 LEU A C   1 
ATOM   1185  O O   . LEU A 1 156 ? 107.911 146.912 146.538 1.00 27.48  ? 156 LEU A O   1 
ATOM   1186  C CB  . LEU A 1 156 ? 110.930 146.476 146.874 1.00 27.48  ? 156 LEU A CB  1 
ATOM   1187  C CG  . LEU A 1 156 ? 112.189 146.805 146.075 1.00 27.48  ? 156 LEU A CG  1 
ATOM   1188  C CD1 . LEU A 1 156 ? 113.107 147.680 146.901 1.00 27.48  ? 156 LEU A CD1 1 
ATOM   1189  C CD2 . LEU A 1 156 ? 112.914 145.556 145.648 1.00 27.48  ? 156 LEU A CD2 1 
ATOM   1190  N N   . GLU A 1 157 ? 108.020 145.047 147.798 1.00 33.61  ? 157 GLU A N   1 
ATOM   1191  C CA  . GLU A 1 157 ? 106.765 145.340 148.472 1.00 33.61  ? 157 GLU A CA  1 
ATOM   1192  C C   . GLU A 1 157 ? 106.704 144.547 149.768 1.00 33.61  ? 157 GLU A C   1 
ATOM   1193  O O   . GLU A 1 157 ? 107.353 143.510 149.913 1.00 33.61  ? 157 GLU A O   1 
ATOM   1194  C CB  . GLU A 1 157 ? 105.560 145.024 147.579 1.00 33.61  ? 157 GLU A CB  1 
ATOM   1195  C CG  . GLU A 1 157 ? 104.883 143.700 147.872 1.00 33.61  ? 157 GLU A CG  1 
ATOM   1196  C CD  . GLU A 1 157 ? 103.909 143.295 146.785 1.00 33.61  ? 157 GLU A CD  1 
ATOM   1197  O OE1 . GLU A 1 157 ? 103.634 144.129 145.899 1.00 33.61  ? 157 GLU A OE1 1 
ATOM   1198  O OE2 . GLU A 1 157 ? 103.414 142.150 146.818 1.00 33.61  ? 157 GLU A OE2 1 
ATOM   1199  N N   . SER A 1 158 ? 105.919 145.055 150.710 1.00 31.87  ? 158 SER A N   1 
ATOM   1200  C CA  . SER A 1 158 ? 105.737 144.414 152.002 1.00 31.87  ? 158 SER A CA  1 
ATOM   1201  C C   . SER A 1 158 ? 104.486 143.546 151.989 1.00 31.87  ? 158 SER A C   1 
ATOM   1202  O O   . SER A 1 158 ? 103.570 143.746 151.189 1.00 31.87  ? 158 SER A O   1 
ATOM   1203  C CB  . SER A 1 158 ? 105.639 145.454 153.117 1.00 31.87  ? 158 SER A CB  1 
ATOM   1204  O OG  . SER A 1 158 ? 104.416 146.158 153.041 1.00 31.87  ? 158 SER A OG  1 
ATOM   1205  N N   . PHE A 1 159 ? 104.458 142.573 152.895 1.00 35.36  ? 159 PHE A N   1 
ATOM   1206  C CA  . PHE A 1 159 ? 103.360 141.620 152.974 1.00 35.36  ? 159 PHE A CA  1 
ATOM   1207  C C   . PHE A 1 159 ? 102.603 141.699 154.288 1.00 35.36  ? 159 PHE A C   1 
ATOM   1208  O O   . PHE A 1 159 ? 101.368 141.711 154.286 1.00 35.36  ? 159 PHE A O   1 
ATOM   1209  C CB  . PHE A 1 159 ? 103.886 140.193 152.766 1.00 35.36  ? 159 PHE A CB  1 
ATOM   1210  C CG  . PHE A 1 159 ? 102.864 139.248 152.214 1.00 35.36  ? 159 PHE A CG  1 
ATOM   1211  C CD1 . PHE A 1 159 ? 101.624 139.705 151.810 1.00 35.36  ? 159 PHE A CD1 1 
ATOM   1212  C CD2 . PHE A 1 159 ? 103.142 137.900 152.101 1.00 35.36  ? 159 PHE A CD2 1 
ATOM   1213  C CE1 . PHE A 1 159 ? 100.682 138.838 151.303 1.00 35.36  ? 159 PHE A CE1 1 
ATOM   1214  C CE2 . PHE A 1 159 ? 102.205 137.029 151.595 1.00 35.36  ? 159 PHE A CE2 1 
ATOM   1215  C CZ  . PHE A 1 159 ? 100.973 137.499 151.196 1.00 35.36  ? 159 PHE A CZ  1 
ATOM   1216  N N   . GLY A 1 160 ? 103.305 141.749 155.413 1.00 34.30  ? 160 GLY A N   1 
ATOM   1217  C CA  . GLY A 1 160 ? 102.646 141.712 156.699 1.00 34.30  ? 160 GLY A CA  1 
ATOM   1218  C C   . GLY A 1 160 ? 102.057 143.012 157.187 1.00 34.30  ? 160 GLY A C   1 
ATOM   1219  O O   . GLY A 1 160 ? 101.407 143.021 158.235 1.00 34.30  ? 160 GLY A O   1 
ATOM   1220  N N   . TYR A 1 161 ? 102.249 144.115 156.469 1.00 33.92  ? 161 TYR A N   1 
ATOM   1221  C CA  . TYR A 1 161 ? 101.780 145.409 156.937 1.00 33.92  ? 161 TYR A CA  1 
ATOM   1222  C C   . TYR A 1 161 ? 101.101 146.163 155.805 1.00 33.92  ? 161 TYR A C   1 
ATOM   1223  O O   . TYR A 1 161 ? 101.526 146.085 154.651 1.00 33.92  ? 161 TYR A O   1 
ATOM   1224  C CB  . TYR A 1 161 ? 102.935 146.240 157.500 1.00 33.92  ? 161 TYR A CB  1 
ATOM   1225  C CG  . TYR A 1 161 ? 103.541 145.660 158.754 1.00 33.92  ? 161 TYR A CG  1 
ATOM   1226  C CD1 . TYR A 1 161 ? 102.975 145.899 159.997 1.00 33.92  ? 161 TYR A CD1 1 
ATOM   1227  C CD2 . TYR A 1 161 ? 104.680 144.873 158.694 1.00 33.92  ? 161 TYR A CD2 1 
ATOM   1228  C CE1 . TYR A 1 161 ? 103.528 145.370 161.144 1.00 33.92  ? 161 TYR A CE1 1 
ATOM   1229  C CE2 . TYR A 1 161 ? 105.239 144.341 159.835 1.00 33.92  ? 161 TYR A CE2 1 
ATOM   1230  C CZ  . TYR A 1 161 ? 104.659 144.592 161.056 1.00 33.92  ? 161 TYR A CZ  1 
ATOM   1231  O OH  . TYR A 1 161 ? 105.213 144.062 162.195 1.00 33.92  ? 161 TYR A OH  1 
ATOM   1232  N N   . THR A 1 162 ? 100.045 146.895 156.150 1.00 35.41  ? 162 THR A N   1 
ATOM   1233  C CA  . THR A 1 162 ? 99.325  147.728 155.203 1.00 35.41  ? 162 THR A CA  1 
ATOM   1234  C C   . THR A 1 162 ? 100.044 149.068 155.055 1.00 35.41  ? 162 THR A C   1 
ATOM   1235  O O   . THR A 1 162 ? 101.049 149.338 155.716 1.00 35.41  ? 162 THR A O   1 
ATOM   1236  C CB  . THR A 1 162 ? 97.882  147.913 155.668 1.00 35.41  ? 162 THR A CB  1 
ATOM   1237  O OG1 . THR A 1 162 ? 97.435  146.714 156.311 1.00 35.41  ? 162 THR A OG1 1 
ATOM   1238  C CG2 . THR A 1 162 ? 96.962  148.191 154.492 1.00 35.41  ? 162 THR A CG2 1 
ATOM   1239  N N   . MET A 1 163 ? 99.531  149.925 154.168 1.00 40.00  ? 163 MET A N   1 
ATOM   1240  C CA  . MET A 1 163 ? 100.100 151.261 154.022 1.00 40.00  ? 163 MET A CA  1 
ATOM   1241  C C   . MET A 1 163 ? 99.982  152.065 155.308 1.00 40.00  ? 163 MET A C   1 
ATOM   1242  O O   . MET A 1 163 ? 100.781 152.977 155.546 1.00 40.00  ? 163 MET A O   1 
ATOM   1243  C CB  . MET A 1 163 ? 99.419  152.007 152.876 1.00 40.00  ? 163 MET A CB  1 
ATOM   1244  C CG  . MET A 1 163 ? 100.108 153.303 152.484 1.00 40.00  ? 163 MET A CG  1 
ATOM   1245  S SD  . MET A 1 163 ? 99.973  153.694 150.732 1.00 40.00  ? 163 MET A SD  1 
ATOM   1246  C CE  . MET A 1 163 ? 101.081 152.484 150.027 1.00 40.00  ? 163 MET A CE  1 
ATOM   1247  N N   . ASN A 1 164 ? 99.000  151.744 156.150 1.00 46.14  ? 164 ASN A N   1 
ATOM   1248  C CA  . ASN A 1 164 ? 98.820  152.463 157.404 1.00 46.14  ? 164 ASN A CA  1 
ATOM   1249  C C   . ASN A 1 164 ? 99.925  152.187 158.413 1.00 46.14  ? 164 ASN A C   1 
ATOM   1250  O O   . ASN A 1 164 ? 99.995  152.886 159.428 1.00 46.14  ? 164 ASN A O   1 
ATOM   1251  C CB  . ASN A 1 164 ? 97.468  152.111 158.023 1.00 46.14  ? 164 ASN A CB  1 
ATOM   1252  C CG  . ASN A 1 164 ? 96.308  152.729 157.276 1.00 46.14  ? 164 ASN A CG  1 
ATOM   1253  O OD1 . ASN A 1 164 ? 95.844  153.816 157.618 1.00 46.14  ? 164 ASN A OD1 1 
ATOM   1254  N ND2 . ASN A 1 164 ? 95.830  152.039 156.247 1.00 46.14  ? 164 ASN A ND2 1 
ATOM   1255  N N   . ASP A 1 165 ? 100.779 151.196 158.170 1.00 42.25  ? 165 ASP A N   1 
ATOM   1256  C CA  . ASP A 1 165 ? 101.814 150.825 159.123 1.00 42.25  ? 165 ASP A CA  1 
ATOM   1257  C C   . ASP A 1 165 ? 103.224 150.837 158.554 1.00 42.25  ? 165 ASP A C   1 
ATOM   1258  O O   . ASP A 1 165 ? 104.173 150.998 159.321 1.00 42.25  ? 165 ASP A O   1 
ATOM   1259  C CB  . ASP A 1 165 ? 101.531 149.430 159.700 1.00 42.25  ? 165 ASP A CB  1 
ATOM   1260  C CG  . ASP A 1 165 ? 100.200 149.358 160.420 1.00 42.25  ? 165 ASP A CG  1 
ATOM   1261  O OD1 . ASP A 1 165 ? 99.744  150.401 160.933 1.00 42.25  ? 165 ASP A OD1 1 
ATOM   1262  O OD2 . ASP A 1 165 ? 99.608  148.259 160.474 1.00 42.25  ? 165 ASP A OD2 1 
ATOM   1263  N N   . LEU A 1 166 ? 103.392 150.674 157.245 1.00 35.45  ? 166 LEU A N   1 
ATOM   1264  C CA  . LEU A 1 166 ? 104.725 150.623 156.657 1.00 35.45  ? 166 LEU A CA  1 
ATOM   1265  C C   . LEU A 1 166 ? 104.686 151.241 155.269 1.00 35.45  ? 166 LEU A C   1 
ATOM   1266  O O   . LEU A 1 166 ? 103.884 150.828 154.428 1.00 35.45  ? 166 LEU A O   1 
ATOM   1267  C CB  . LEU A 1 166 ? 105.234 149.183 156.585 1.00 35.45  ? 166 LEU A CB  1 
ATOM   1268  C CG  . LEU A 1 166 ? 106.658 148.998 156.068 1.00 35.45  ? 166 LEU A CG  1 
ATOM   1269  C CD1 . LEU A 1 166 ? 107.643 149.634 157.023 1.00 35.45  ? 166 LEU A CD1 1 
ATOM   1270  C CD2 . LEU A 1 166 ? 106.968 147.528 155.883 1.00 35.45  ? 166 LEU A CD2 1 
ATOM   1271  N N   . ILE A 1 167 ? 105.553 152.223 155.034 1.00 32.58  ? 167 ILE A N   1 
ATOM   1272  C CA  . ILE A 1 167 ? 105.619 152.937 153.765 1.00 32.58  ? 167 ILE A CA  1 
ATOM   1273  C C   . ILE A 1 167 ? 107.041 152.852 153.233 1.00 32.58  ? 167 ILE A C   1 
ATOM   1274  O O   . ILE A 1 167 ? 107.987 153.257 153.917 1.00 32.58  ? 167 ILE A O   1 
ATOM   1275  C CB  . ILE A 1 167 ? 105.194 154.409 153.915 1.00 32.58  ? 167 ILE A CB  1 
ATOM   1276  C CG1 . ILE A 1 167 ? 103.722 154.506 154.309 1.00 32.58  ? 167 ILE A CG1 1 
ATOM   1277  C CG2 . ILE A 1 167 ? 105.453 155.169 152.631 1.00 32.58  ? 167 ILE A CG2 1 
ATOM   1278  C CD1 . ILE A 1 167 ? 103.209 155.924 154.370 1.00 32.58  ? 167 ILE A CD1 1 
ATOM   1279  N N   . PHE A 1 168 ? 107.189 152.343 152.015 1.00 30.61  ? 168 PHE A N   1 
ATOM   1280  C CA  . PHE A 1 168 ? 108.484 152.241 151.361 1.00 30.61  ? 168 PHE A CA  1 
ATOM   1281  C C   . PHE A 1 168 ? 108.704 153.429 150.434 1.00 30.61  ? 168 PHE A C   1 
ATOM   1282  O O   . PHE A 1 168 ? 107.753 154.029 149.928 1.00 30.61  ? 168 PHE A O   1 
ATOM   1283  C CB  . PHE A 1 168 ? 108.596 150.946 150.557 1.00 30.61  ? 168 PHE A CB  1 
ATOM   1284  C CG  . PHE A 1 168 ? 108.868 149.732 151.387 1.00 30.61  ? 168 PHE A CG  1 
ATOM   1285  C CD1 . PHE A 1 168 ? 109.206 149.846 152.719 1.00 30.61  ? 168 PHE A CD1 1 
ATOM   1286  C CD2 . PHE A 1 168 ? 108.789 148.472 150.828 1.00 30.61  ? 168 PHE A CD2 1 
ATOM   1287  C CE1 . PHE A 1 168 ? 109.455 148.725 153.479 1.00 30.61  ? 168 PHE A CE1 1 
ATOM   1288  C CE2 . PHE A 1 168 ? 109.037 147.351 151.582 1.00 30.61  ? 168 PHE A CE2 1 
ATOM   1289  C CZ  . PHE A 1 168 ? 109.371 147.477 152.908 1.00 30.61  ? 168 PHE A CZ  1 
ATOM   1290  N N   . GLU A 1 169 ? 109.973 153.761 150.215 1.00 34.87  ? 169 GLU A N   1 
ATOM   1291  C CA  . GLU A 1 169 ? 110.339 154.804 149.267 1.00 34.87  ? 169 GLU A CA  1 
ATOM   1292  C C   . GLU A 1 169 ? 111.818 154.664 148.945 1.00 34.87  ? 169 GLU A C   1 
ATOM   1293  O O   . GLU A 1 169 ? 112.581 154.062 149.703 1.00 34.87  ? 169 GLU A O   1 
ATOM   1294  C CB  . GLU A 1 169 ? 110.030 156.199 149.816 1.00 34.87  ? 169 GLU A CB  1 
ATOM   1295  C CG  . GLU A 1 169 ? 110.683 156.496 151.147 1.00 34.87  ? 169 GLU A CG  1 
ATOM   1296  C CD  . GLU A 1 169 ? 110.077 157.704 151.829 1.00 34.87  ? 169 GLU A CD  1 
ATOM   1297  O OE1 . GLU A 1 169 ? 108.912 158.034 151.523 1.00 34.87  ? 169 GLU A OE1 1 
ATOM   1298  O OE2 . GLU A 1 169 ? 110.763 158.324 152.667 1.00 34.87  ? 169 GLU A OE2 1 
ATOM   1299  N N   . TRP A 1 170 ? 112.214 155.231 147.810 1.00 36.67  ? 170 TRP A N   1 
ATOM   1300  C CA  . TRP A 1 170 ? 113.601 155.157 147.382 1.00 36.67  ? 170 TRP A CA  1 
ATOM   1301  C C   . TRP A 1 170 ? 114.450 156.163 148.154 1.00 36.67  ? 170 TRP A C   1 
ATOM   1302  O O   . TRP A 1 170 ? 113.960 156.923 148.993 1.00 36.67  ? 170 TRP A O   1 
ATOM   1303  C CB  . TRP A 1 170 ? 113.714 155.408 145.882 1.00 36.67  ? 170 TRP A CB  1 
ATOM   1304  C CG  . TRP A 1 170 ? 113.417 154.221 145.031 1.00 36.67  ? 170 TRP A CG  1 
ATOM   1305  C CD1 . TRP A 1 170 ? 112.464 154.133 144.065 1.00 36.67  ? 170 TRP A CD1 1 
ATOM   1306  C CD2 . TRP A 1 170 ? 114.084 152.955 145.053 1.00 36.67  ? 170 TRP A CD2 1 
ATOM   1307  N NE1 . TRP A 1 170 ? 112.491 152.891 143.486 1.00 36.67  ? 170 TRP A NE1 1 
ATOM   1308  C CE2 . TRP A 1 170 ? 113.479 152.149 144.075 1.00 36.67  ? 170 TRP A CE2 1 
ATOM   1309  C CE3 . TRP A 1 170 ? 115.133 152.425 145.804 1.00 36.67  ? 170 TRP A CE3 1 
ATOM   1310  C CZ2 . TRP A 1 170 ? 113.883 150.841 143.833 1.00 36.67  ? 170 TRP A CZ2 1 
ATOM   1311  C CZ3 . TRP A 1 170 ? 115.532 151.127 145.560 1.00 36.67  ? 170 TRP A CZ3 1 
ATOM   1312  C CH2 . TRP A 1 170 ? 114.909 150.350 144.584 1.00 36.67  ? 170 TRP A CH2 1 
ATOM   1313  N N   . GLN A 1 171 ? 115.744 156.169 147.859 1.00 52.53  ? 171 GLN A N   1 
ATOM   1314  C CA  . GLN A 1 171 ? 116.675 157.108 148.464 1.00 52.53  ? 171 GLN A CA  1 
ATOM   1315  C C   . GLN A 1 171 ? 116.808 158.346 147.587 1.00 52.53  ? 171 GLN A C   1 
ATOM   1316  O O   . GLN A 1 171 ? 116.737 158.270 146.358 1.00 52.53  ? 171 GLN A O   1 
ATOM   1317  C CB  . GLN A 1 171 ? 118.040 156.451 148.669 1.00 52.53  ? 171 GLN A CB  1 
ATOM   1318  C CG  . GLN A 1 171 ? 119.072 157.334 149.339 1.00 52.53  ? 171 GLN A CG  1 
ATOM   1319  C CD  . GLN A 1 171 ? 120.405 156.637 149.501 1.00 52.53  ? 171 GLN A CD  1 
ATOM   1320  O OE1 . GLN A 1 171 ? 120.463 155.446 149.801 1.00 52.53  ? 171 GLN A OE1 1 
ATOM   1321  N NE2 . GLN A 1 171 ? 121.487 157.377 149.296 1.00 52.53  ? 171 GLN A NE2 1 
ATOM   1322  N N   . ASP A 1 172 ? 116.998 159.497 148.237 1.00 65.32  ? 172 ASP A N   1 
ATOM   1323  C CA  . ASP A 1 172 ? 117.007 160.766 147.514 1.00 65.32  ? 172 ASP A CA  1 
ATOM   1324  C C   . ASP A 1 172 ? 118.159 160.843 146.518 1.00 65.32  ? 172 ASP A C   1 
ATOM   1325  O O   . ASP A 1 172 ? 117.976 161.300 145.384 1.00 65.32  ? 172 ASP A O   1 
ATOM   1326  C CB  . ASP A 1 172 ? 117.078 161.927 148.504 1.00 65.32  ? 172 ASP A CB  1 
ATOM   1327  C CG  . ASP A 1 172 ? 116.384 163.170 147.992 1.00 65.32  ? 172 ASP A CG  1 
ATOM   1328  O OD1 . ASP A 1 172 ? 116.349 163.367 146.759 1.00 65.32  ? 172 ASP A OD1 1 
ATOM   1329  O OD2 . ASP A 1 172 ? 115.869 163.949 148.821 1.00 65.32  ? 172 ASP A OD2 1 
ATOM   1330  N N   . GLU A 1 173 ? 119.349 160.405 146.919 1.00 66.00  ? 173 GLU A N   1 
ATOM   1331  C CA  . GLU A 1 173 ? 120.537 160.474 146.076 1.00 66.00  ? 173 GLU A CA  1 
ATOM   1332  C C   . GLU A 1 173 ? 121.072 159.071 145.828 1.00 66.00  ? 173 GLU A C   1 
ATOM   1333  O O   . GLU A 1 173 ? 121.282 158.307 146.777 1.00 66.00  ? 173 GLU A O   1 
ATOM   1334  C CB  . GLU A 1 173 ? 121.617 161.347 146.719 1.00 66.00  ? 173 GLU A CB  1 
ATOM   1335  C CG  . GLU A 1 173 ? 122.961 161.287 146.012 1.00 66.00  ? 173 GLU A CG  1 
ATOM   1336  C CD  . GLU A 1 173 ? 123.895 162.403 146.437 1.00 66.00  ? 173 GLU A CD  1 
ATOM   1337  O OE1 . GLU A 1 173 ? 124.208 162.493 147.643 1.00 66.00  ? 173 GLU A OE1 1 
ATOM   1338  O OE2 . GLU A 1 173 ? 124.318 163.190 145.564 1.00 66.00  ? 173 GLU A OE2 1 
ATOM   1339  N N   . ALA A 1 174 ? 121.305 158.747 144.553 1.00 52.24  ? 174 ALA A N   1 
ATOM   1340  C CA  . ALA A 1 174 ? 121.812 157.451 144.117 1.00 52.24  ? 174 ALA A CA  1 
ATOM   1341  C C   . ALA A 1 174 ? 120.970 156.312 144.680 1.00 52.24  ? 174 ALA A C   1 
ATOM   1342  O O   . ALA A 1 174 ? 121.430 155.581 145.566 1.00 52.24  ? 174 ALA A O   1 
ATOM   1343  C CB  . ALA A 1 174 ? 123.275 157.280 144.528 1.00 52.24  ? 174 ALA A CB  1 
ATOM   1344  N N   . PRO A 1 175 ? 119.736 156.133 144.205 1.00 38.85  ? 175 PRO A N   1 
ATOM   1345  C CA  . PRO A 1 175 ? 118.887 155.062 144.743 1.00 38.85  ? 175 PRO A CA  1 
ATOM   1346  C C   . PRO A 1 175 ? 119.411 153.672 144.425 1.00 38.85  ? 175 PRO A C   1 
ATOM   1347  O O   . PRO A 1 175 ? 119.542 152.836 145.322 1.00 38.85  ? 175 PRO A O   1 
ATOM   1348  C CB  . PRO A 1 175 ? 117.533 155.314 144.066 1.00 38.85  ? 175 PRO A CB  1 
ATOM   1349  C CG  . PRO A 1 175 ? 117.604 156.721 143.563 1.00 38.85  ? 175 PRO A CG  1 
ATOM   1350  C CD  . PRO A 1 175 ? 119.029 156.934 143.196 1.00 38.85  ? 175 PRO A CD  1 
ATOM   1351  N N   . VAL A 1 176 ? 119.714 153.408 143.159 1.00 32.10  ? 176 VAL A N   1 
ATOM   1352  C CA  . VAL A 1 176 ? 120.231 152.115 142.727 1.00 32.10  ? 176 VAL A CA  1 
ATOM   1353  C C   . VAL A 1 176 ? 121.582 152.336 142.066 1.00 32.10  ? 176 VAL A C   1 
ATOM   1354  O O   . VAL A 1 176 ? 121.700 153.146 141.140 1.00 32.10  ? 176 VAL A O   1 
ATOM   1355  C CB  . VAL A 1 176 ? 119.257 151.401 141.772 1.00 32.10  ? 176 VAL A CB  1 
ATOM   1356  C CG1 . VAL A 1 176 ? 118.621 152.395 140.824 1.00 32.10  ? 176 VAL A CG1 1 
ATOM   1357  C CG2 . VAL A 1 176 ? 119.977 150.314 140.999 1.00 32.10  ? 176 VAL A CG2 1 
ATOM   1358  N N   . GLN A 1 177 ? 122.594 151.624 142.542 1.00 31.82  ? 177 GLN A N   1 
ATOM   1359  C CA  . GLN A 1 177 ? 123.948 151.734 142.025 1.00 31.82  ? 177 GLN A CA  1 
ATOM   1360  C C   . GLN A 1 177 ? 124.334 150.454 141.299 1.00 31.82  ? 177 GLN A C   1 
ATOM   1361  O O   . GLN A 1 177 ? 123.619 149.450 141.330 1.00 31.82  ? 177 GLN A O   1 
ATOM   1362  C CB  . GLN A 1 177 ? 124.938 152.024 143.156 1.00 31.82  ? 177 GLN A CB  1 
ATOM   1363  C CG  . GLN A 1 177 ? 124.416 153.000 144.189 1.00 31.82  ? 177 GLN A CG  1 
ATOM   1364  C CD  . GLN A 1 177 ? 125.283 153.049 145.427 1.00 31.82  ? 177 GLN A CD  1 
ATOM   1365  O OE1 . GLN A 1 177 ? 126.449 152.661 145.395 1.00 31.82  ? 177 GLN A OE1 1 
ATOM   1366  N NE2 . GLN A 1 177 ? 124.715 153.521 146.528 1.00 31.82  ? 177 GLN A NE2 1 
ATOM   1367  N N   . VAL A 1 178 ? 125.480 150.504 140.629 1.00 31.59  ? 178 VAL A N   1 
ATOM   1368  C CA  . VAL A 1 178 ? 126.030 149.361 139.912 1.00 31.59  ? 178 VAL A CA  1 
ATOM   1369  C C   . VAL A 1 178 ? 127.514 149.270 140.231 1.00 31.59  ? 178 VAL A C   1 
ATOM   1370  O O   . VAL A 1 178 ? 128.217 150.286 140.216 1.00 31.59  ? 178 VAL A O   1 
ATOM   1371  C CB  . VAL A 1 178 ? 125.808 149.477 138.393 1.00 31.59  ? 178 VAL A CB  1 
ATOM   1372  C CG1 . VAL A 1 178 ? 126.599 148.415 137.659 1.00 31.59  ? 178 VAL A CG1 1 
ATOM   1373  C CG2 . VAL A 1 178 ? 124.334 149.356 138.063 1.00 31.59  ? 178 VAL A CG2 1 
ATOM   1374  N N   . ALA A 1 179 ? 127.985 148.062 140.530 1.00 36.99  ? 179 ALA A N   1 
ATOM   1375  C CA  . ALA A 1 179 ? 129.401 147.860 140.799 1.00 36.99  ? 179 ALA A CA  1 
ATOM   1376  C C   . ALA A 1 179 ? 130.229 148.227 139.576 1.00 36.99  ? 179 ALA A C   1 
ATOM   1377  O O   . ALA A 1 179 ? 129.839 147.955 138.437 1.00 36.99  ? 179 ALA A O   1 
ATOM   1378  C CB  . ALA A 1 179 ? 129.665 146.410 141.200 1.00 36.99  ? 179 ALA A CB  1 
ATOM   1379  N N   . GLU A 1 180 ? 131.378 148.854 139.819 1.00 44.37  ? 180 GLU A N   1 
ATOM   1380  C CA  . GLU A 1 180 ? 132.222 149.318 138.727 1.00 44.37  ? 180 GLU A CA  1 
ATOM   1381  C C   . GLU A 1 180 ? 132.717 148.145 137.891 1.00 44.37  ? 180 GLU A C   1 
ATOM   1382  O O   . GLU A 1 180 ? 133.113 147.104 138.421 1.00 44.37  ? 180 GLU A O   1 
ATOM   1383  C CB  . GLU A 1 180 ? 133.409 150.109 139.276 1.00 44.37  ? 180 GLU A CB  1 
ATOM   1384  N N   . GLY A 1 181 ? 132.690 148.321 136.573 1.00 42.36  ? 181 GLY A N   1 
ATOM   1385  C CA  . GLY A 1 181 ? 133.166 147.291 135.674 1.00 42.36  ? 181 GLY A CA  1 
ATOM   1386  C C   . GLY A 1 181 ? 132.245 146.108 135.501 1.00 42.36  ? 181 GLY A C   1 
ATOM   1387  O O   . GLY A 1 181 ? 132.709 145.031 135.117 1.00 42.36  ? 181 GLY A O   1 
ATOM   1388  N N   . LEU A 1 182 ? 130.953 146.266 135.780 1.00 48.21  ? 182 LEU A N   1 
ATOM   1389  C CA  . LEU A 1 182 ? 130.009 145.175 135.580 1.00 48.21  ? 182 LEU A CA  1 
ATOM   1390  C C   . LEU A 1 182 ? 129.829 144.900 134.093 1.00 48.21  ? 182 LEU A C   1 
ATOM   1391  O O   . LEU A 1 182 ? 129.613 145.822 133.301 1.00 48.21  ? 182 LEU A O   1 
ATOM   1392  C CB  . LEU A 1 182 ? 128.663 145.511 136.219 1.00 48.21  ? 182 LEU A CB  1 
ATOM   1393  C CG  . LEU A 1 182 ? 127.538 144.530 135.894 1.00 48.21  ? 182 LEU A CG  1 
ATOM   1394  C CD1 . LEU A 1 182 ? 127.854 143.159 136.461 1.00 48.21  ? 182 LEU A CD1 1 
ATOM   1395  C CD2 . LEU A 1 182 ? 126.210 145.036 136.419 1.00 48.21  ? 182 LEU A CD2 1 
ATOM   1396  N N   . THR A 1 183 ? 129.917 143.628 133.715 1.00 47.47  ? 183 THR A N   1 
ATOM   1397  C CA  . THR A 1 183 ? 129.766 143.203 132.330 1.00 47.47  ? 183 THR A CA  1 
ATOM   1398  C C   . THR A 1 183 ? 128.637 142.190 132.232 1.00 47.47  ? 183 THR A C   1 
ATOM   1399  O O   . THR A 1 183 ? 128.580 141.241 133.020 1.00 47.47  ? 183 THR A O   1 
ATOM   1400  C CB  . THR A 1 183 ? 131.056 142.584 131.790 1.00 47.47  ? 183 THR A CB  1 
ATOM   1401  O OG1 . THR A 1 183 ? 131.058 141.178 132.064 1.00 47.47  ? 183 THR A OG1 1 
ATOM   1402  C CG2 . THR A 1 183 ? 132.273 143.221 132.438 1.00 47.47  ? 183 THR A CG2 1 
ATOM   1403  N N   . LEU A 1 184 ? 127.760 142.390 131.282 1.00 45.28  ? 184 LEU A N   1 
ATOM   1404  C CA  . LEU A 1 184 ? 126.756 141.364 131.061 1.00 45.28  ? 184 LEU A CA  1 
ATOM   1405  C C   . LEU A 1 184 ? 127.219 140.404 129.970 1.00 45.28  ? 184 LEU A C   1 
ATOM   1406  O O   . LEU A 1 184 ? 127.992 140.786 129.085 1.00 45.28  ? 184 LEU A O   1 
ATOM   1407  C CB  . LEU A 1 184 ? 125.426 141.994 130.661 1.00 45.28  ? 184 LEU A CB  1 
ATOM   1408  C CG  . LEU A 1 184 ? 124.527 142.475 131.800 1.00 45.28  ? 184 LEU A CG  1 
ATOM   1409  C CD1 . LEU A 1 184 ? 125.009 143.805 132.351 1.00 45.28  ? 184 LEU A CD1 1 
ATOM   1410  C CD2 . LEU A 1 184 ? 123.088 142.579 131.332 1.00 45.28  ? 184 LEU A CD2 1 
ATOM   1411  N N   . PRO A 1 185 ? 126.771 139.146 130.010 1.00 48.12  ? 185 PRO A N   1 
ATOM   1412  C CA  . PRO A 1 185 ? 127.267 138.182 129.016 1.00 48.12  ? 185 PRO A CA  1 
ATOM   1413  C C   . PRO A 1 185 ? 126.774 138.460 127.609 1.00 48.12  ? 185 PRO A C   1 
ATOM   1414  O O   . PRO A 1 185 ? 127.549 138.336 126.653 1.00 48.12  ? 185 PRO A O   1 
ATOM   1415  C CB  . PRO A 1 185 ? 126.750 136.840 129.550 1.00 48.12  ? 185 PRO A CB  1 
ATOM   1416  C CG  . PRO A 1 185 ? 125.535 137.195 130.329 1.00 48.12  ? 185 PRO A CG  1 
ATOM   1417  C CD  . PRO A 1 185 ? 125.827 138.528 130.956 1.00 48.12  ? 185 PRO A CD  1 
ATOM   1418  N N   . GLN A 1 186 ? 125.510 138.842 127.452 1.00 43.54  ? 186 GLN A N   1 
ATOM   1419  C CA  . GLN A 1 186 ? 124.912 139.014 126.136 1.00 43.54  ? 186 GLN A CA  1 
ATOM   1420  C C   . GLN A 1 186 ? 124.360 140.407 125.882 1.00 43.54  ? 186 GLN A C   1 
ATOM   1421  O O   . GLN A 1 186 ? 124.439 140.883 124.750 1.00 43.54  ? 186 GLN A O   1 
ATOM   1422  C CB  . GLN A 1 186 ? 123.786 137.988 125.930 1.00 43.54  ? 186 GLN A CB  1 
ATOM   1423  C CG  . GLN A 1 186 ? 123.082 138.085 124.590 1.00 43.54  ? 186 GLN A CG  1 
ATOM   1424  C CD  . GLN A 1 186 ? 124.014 137.856 123.419 1.00 43.54  ? 186 GLN A CD  1 
ATOM   1425  O OE1 . GLN A 1 186 ? 125.042 137.193 123.548 1.00 43.54  ? 186 GLN A OE1 1 
ATOM   1426  N NE2 . GLN A 1 186 ? 123.658 138.407 122.266 1.00 43.54  ? 186 GLN A NE2 1 
ATOM   1427  N N   . PHE A 1 187 ? 123.814 141.073 126.892 1.00 40.46  ? 187 PHE A N   1 
ATOM   1428  C CA  . PHE A 1 187 ? 123.217 142.386 126.726 1.00 40.46  ? 187 PHE A CA  1 
ATOM   1429  C C   . PHE A 1 187 ? 124.177 143.467 127.215 1.00 40.46  ? 187 PHE A C   1 
ATOM   1430  O O   . PHE A 1 187 ? 125.302 143.195 127.637 1.00 40.46  ? 187 PHE A O   1 
ATOM   1431  C CB  . PHE A 1 187 ? 121.886 142.464 127.476 1.00 40.46  ? 187 PHE A CB  1 
ATOM   1432  C CG  . PHE A 1 187 ? 120.869 141.462 127.015 1.00 40.46  ? 187 PHE A CG  1 
ATOM   1433  C CD1 . PHE A 1 187 ? 120.922 140.150 127.448 1.00 40.46  ? 187 PHE A CD1 1 
ATOM   1434  C CD2 . PHE A 1 187 ? 119.855 141.836 126.156 1.00 40.46  ? 187 PHE A CD2 1 
ATOM   1435  C CE1 . PHE A 1 187 ? 119.988 139.230 127.025 1.00 40.46  ? 187 PHE A CE1 1 
ATOM   1436  C CE2 . PHE A 1 187 ? 118.917 140.918 125.731 1.00 40.46  ? 187 PHE A CE2 1 
ATOM   1437  C CZ  . PHE A 1 187 ? 118.984 139.615 126.166 1.00 40.46  ? 187 PHE A CZ  1 
ATOM   1438  N N   . LEU A 1 188 ? 123.725 144.715 127.142 1.00 43.15  ? 188 LEU A N   1 
ATOM   1439  C CA  . LEU A 1 188 ? 124.415 145.836 127.764 1.00 43.15  ? 188 LEU A CA  1 
ATOM   1440  C C   . LEU A 1 188 ? 123.390 146.649 128.537 1.00 43.15  ? 188 LEU A C   1 
ATOM   1441  O O   . LEU A 1 188 ? 122.315 146.957 128.013 1.00 43.15  ? 188 LEU A O   1 
ATOM   1442  C CB  . LEU A 1 188 ? 125.141 146.706 126.730 1.00 43.15  ? 188 LEU A CB  1 
ATOM   1443  C CG  . LEU A 1 188 ? 124.339 147.370 125.610 1.00 43.15  ? 188 LEU A CG  1 
ATOM   1444  C CD1 . LEU A 1 188 ? 124.068 148.830 125.936 1.00 43.15  ? 188 LEU A CD1 1 
ATOM   1445  C CD2 . LEU A 1 188 ? 125.072 147.247 124.284 1.00 43.15  ? 188 LEU A CD2 1 
ATOM   1446  N N   . LEU A 1 189 ? 123.717 146.985 129.779 1.00 41.64  ? 189 LEU A N   1 
ATOM   1447  C CA  . LEU A 1 189 ? 122.778 147.640 130.679 1.00 41.64  ? 189 LEU A CA  1 
ATOM   1448  C C   . LEU A 1 189 ? 122.875 149.150 130.503 1.00 41.64  ? 189 LEU A C   1 
ATOM   1449  O O   . LEU A 1 189 ? 123.934 149.740 130.742 1.00 41.64  ? 189 LEU A O   1 
ATOM   1450  C CB  . LEU A 1 189 ? 123.066 147.242 132.125 1.00 41.64  ? 189 LEU A CB  1 
ATOM   1451  C CG  . LEU A 1 189 ? 121.910 147.284 133.124 1.00 41.64  ? 189 LEU A CG  1 
ATOM   1452  C CD1 . LEU A 1 189 ? 122.123 146.241 134.201 1.00 41.64  ? 189 LEU A CD1 1 
ATOM   1453  C CD2 . LEU A 1 189 ? 121.786 148.657 133.747 1.00 41.64  ? 189 LEU A CD2 1 
ATOM   1454  N N   . LYS A 1 190 ? 121.775 149.770 130.085 1.00 42.86  ? 190 LYS A N   1 
ATOM   1455  C CA  . LYS A 1 190 ? 121.747 151.218 129.945 1.00 42.86  ? 190 LYS A CA  1 
ATOM   1456  C C   . LYS A 1 190 ? 121.865 151.880 131.310 1.00 42.86  ? 190 LYS A C   1 
ATOM   1457  O O   . LYS A 1 190 ? 121.263 151.432 132.289 1.00 42.86  ? 190 LYS A O   1 
ATOM   1458  C CB  . LYS A 1 190 ? 120.464 151.667 129.251 1.00 42.86  ? 190 LYS A CB  1 
ATOM   1459  C CG  . LYS A 1 190 ? 120.560 151.698 127.738 1.00 42.86  ? 190 LYS A CG  1 
ATOM   1460  C CD  . LYS A 1 190 ? 119.309 152.298 127.124 1.00 42.86  ? 190 LYS A CD  1 
ATOM   1461  C CE  . LYS A 1 190 ? 119.053 153.695 127.660 1.00 42.86  ? 190 LYS A CE  1 
ATOM   1462  N NZ  . LYS A 1 190 ? 117.699 154.190 127.291 1.00 42.86  ? 190 LYS A NZ  1 
ATOM   1463  N N   . GLU A 1 191 ? 122.644 152.961 131.365 1.00 45.40  ? 191 GLU A N   1 
ATOM   1464  C CA  . GLU A 1 191 ? 122.949 153.591 132.645 1.00 45.40  ? 191 GLU A CA  1 
ATOM   1465  C C   . GLU A 1 191 ? 121.690 154.098 133.333 1.00 45.40  ? 191 GLU A C   1 
ATOM   1466  O O   . GLU A 1 191 ? 121.531 153.936 134.549 1.00 45.40  ? 191 GLU A O   1 
ATOM   1467  C CB  . GLU A 1 191 ? 123.945 154.732 132.442 1.00 45.40  ? 191 GLU A CB  1 
ATOM   1468  C CG  . GLU A 1 191 ? 124.303 155.482 133.715 1.00 45.40  ? 191 GLU A CG  1 
ATOM   1469  C CD  . GLU A 1 191 ? 123.415 156.690 133.957 1.00 45.40  ? 191 GLU A CD  1 
ATOM   1470  O OE1 . GLU A 1 191 ? 122.570 156.991 133.088 1.00 45.40  ? 191 GLU A OE1 1 
ATOM   1471  O OE2 . GLU A 1 191 ? 123.562 157.337 135.015 1.00 45.40  ? 191 GLU A OE2 1 
ATOM   1472  N N   A GLU A 1 192 ? 120.785 154.716 132.578 0.42 43.34  ? 192 GLU A N   1 
ATOM   1473  N N   B GLU A 1 192 ? 120.785 154.716 132.578 0.58 43.34  ? 192 GLU A N   1 
ATOM   1474  C CA  A GLU A 1 192 ? 119.577 155.274 133.169 0.42 43.34  ? 192 GLU A CA  1 
ATOM   1475  C CA  B GLU A 1 192 ? 119.577 155.274 133.169 0.58 43.34  ? 192 GLU A CA  1 
ATOM   1476  C C   A GLU A 1 192 ? 118.620 154.163 133.582 0.42 43.34  ? 192 GLU A C   1 
ATOM   1477  C C   B GLU A 1 192 ? 118.620 154.163 133.582 0.58 43.34  ? 192 GLU A C   1 
ATOM   1478  O O   A GLU A 1 192 ? 118.388 153.214 132.828 0.42 43.34  ? 192 GLU A O   1 
ATOM   1479  O O   B GLU A 1 192 ? 118.388 153.214 132.828 0.58 43.34  ? 192 GLU A O   1 
ATOM   1480  C CB  A GLU A 1 192 ? 118.895 156.223 132.187 0.42 43.34  ? 192 GLU A CB  1 
ATOM   1481  C CB  B GLU A 1 192 ? 118.895 156.223 132.187 0.58 43.34  ? 192 GLU A CB  1 
ATOM   1482  C CG  A GLU A 1 192 ? 119.257 157.682 132.398 0.42 43.34  ? 192 GLU A CG  1 
ATOM   1483  C CG  B GLU A 1 192 ? 119.262 157.681 132.395 0.58 43.34  ? 192 GLU A CG  1 
ATOM   1484  C CD  A GLU A 1 192 ? 118.775 158.212 133.733 0.42 43.34  ? 192 GLU A CD  1 
ATOM   1485  C CD  B GLU A 1 192 ? 118.787 158.214 133.732 0.58 43.34  ? 192 GLU A CD  1 
ATOM   1486  O OE1 A GLU A 1 192 ? 117.723 157.744 134.216 0.42 43.34  ? 192 GLU A OE1 1 
ATOM   1487  O OE1 B GLU A 1 192 ? 117.734 157.751 134.218 0.58 43.34  ? 192 GLU A OE1 1 
ATOM   1488  O OE2 A GLU A 1 192 ? 119.449 159.095 134.303 0.42 43.34  ? 192 GLU A OE2 1 
ATOM   1489  O OE2 B GLU A 1 192 ? 119.467 159.095 134.298 0.58 43.34  ? 192 GLU A OE2 1 
ATOM   1490  N N   . LYS A 1 193 ? 118.068 154.285 134.788 1.00 37.67  ? 193 LYS A N   1 
ATOM   1491  C CA  . LYS A 1 193 ? 117.135 153.313 135.336 1.00 37.67  ? 193 LYS A CA  1 
ATOM   1492  C C   . LYS A 1 193 ? 115.911 154.042 135.867 1.00 37.67  ? 193 LYS A C   1 
ATOM   1493  O O   . LYS A 1 193 ? 116.034 155.084 136.516 1.00 37.67  ? 193 LYS A O   1 
ATOM   1494  C CB  . LYS A 1 193 ? 117.785 152.493 136.452 1.00 37.67  ? 193 LYS A CB  1 
ATOM   1495  C CG  . LYS A 1 193 ? 119.112 151.873 136.062 1.00 37.67  ? 193 LYS A CG  1 
ATOM   1496  C CD  . LYS A 1 193 ? 119.798 151.237 137.251 1.00 37.67  ? 193 LYS A CD  1 
ATOM   1497  C CE  . LYS A 1 193 ? 121.153 150.679 136.861 1.00 37.67  ? 193 LYS A CE  1 
ATOM   1498  N NZ  . LYS A 1 193 ? 122.090 151.749 136.426 1.00 37.67  ? 193 LYS A NZ  1 
ATOM   1499  N N   . ASP A 1 194 ? 114.734 153.493 135.592 1.00 35.66  ? 194 ASP A N   1 
ATOM   1500  C CA  . ASP A 1 194 ? 113.483 154.123 135.983 1.00 35.66  ? 194 ASP A CA  1 
ATOM   1501  C C   . ASP A 1 194 ? 113.091 153.712 137.396 1.00 35.66  ? 194 ASP A C   1 
ATOM   1502  O O   . ASP A 1 194 ? 113.370 152.597 137.841 1.00 35.66  ? 194 ASP A O   1 
ATOM   1503  C CB  . ASP A 1 194 ? 112.367 153.753 135.006 1.00 35.66  ? 194 ASP A CB  1 
ATOM   1504  C CG  . ASP A 1 194 ? 111.373 154.878 134.801 1.00 35.66  ? 194 ASP A CG  1 
ATOM   1505  O OD1 . ASP A 1 194 ? 111.710 156.036 135.125 1.00 35.66  ? 194 ASP A OD1 1 
ATOM   1506  O OD2 . ASP A 1 194 ? 110.256 154.605 134.315 1.00 35.66  ? 194 ASP A OD2 1 
ATOM   1507  N N   . LEU A 1 195 ? 112.440 154.634 138.103 1.00 33.14  ? 195 LEU A N   1 
ATOM   1508  C CA  . LEU A 1 195 ? 111.926 154.392 139.445 1.00 33.14  ? 195 LEU A CA  1 
ATOM   1509  C C   . LEU A 1 195 ? 110.457 154.781 139.481 1.00 33.14  ? 195 LEU A C   1 
ATOM   1510  O O   . LEU A 1 195 ? 110.094 155.875 139.041 1.00 33.14  ? 195 LEU A O   1 
ATOM   1511  C CB  . LEU A 1 195 ? 112.712 155.186 140.491 1.00 33.14  ? 195 LEU A CB  1 
ATOM   1512  C CG  . LEU A 1 195 ? 114.219 155.289 140.259 1.00 33.14  ? 195 LEU A CG  1 
ATOM   1513  C CD1 . LEU A 1 195 ? 114.832 156.315 141.192 1.00 33.14  ? 195 LEU A CD1 1 
ATOM   1514  C CD2 . LEU A 1 195 ? 114.879 153.938 140.442 1.00 33.14  ? 195 LEU A CD2 1 
ATOM   1515  N N   . ARG A 1 196 ? 109.616 153.893 140.006 1.00 36.47  ? 196 ARG A N   1 
ATOM   1516  C CA  . ARG A 1 196 ? 108.176 154.103 139.998 1.00 36.47  ? 196 ARG A CA  1 
ATOM   1517  C C   . ARG A 1 196 ? 107.578 153.629 141.314 1.00 36.47  ? 196 ARG A C   1 
ATOM   1518  O O   . ARG A 1 196 ? 108.256 153.031 142.152 1.00 36.47  ? 196 ARG A O   1 
ATOM   1519  C CB  . ARG A 1 196 ? 107.511 153.376 138.823 1.00 36.47  ? 196 ARG A CB  1 
ATOM   1520  C CG  . ARG A 1 196 ? 107.855 153.943 137.458 1.00 36.47  ? 196 ARG A CG  1 
ATOM   1521  C CD  . ARG A 1 196 ? 107.498 152.963 136.356 1.00 36.47  ? 196 ARG A CD  1 
ATOM   1522  N NE  . ARG A 1 196 ? 106.154 152.424 136.524 1.00 36.47  ? 196 ARG A NE  1 
ATOM   1523  C CZ  . ARG A 1 196 ? 105.056 152.986 136.037 1.00 36.47  ? 196 ARG A CZ  1 
ATOM   1524  N NH1 . ARG A 1 196 ? 105.106 154.107 135.338 1.00 36.47  ? 196 ARG A NH1 1 
ATOM   1525  N NH2 . ARG A 1 196 ? 103.879 152.408 136.258 1.00 36.47  ? 196 ARG A NH2 1 
ATOM   1526  N N   . TYR A 1 197 ? 106.288 153.911 141.490 1.00 33.89  ? 197 TYR A N   1 
ATOM   1527  C CA  . TYR A 1 197 ? 105.517 153.465 142.647 1.00 33.89  ? 197 TYR A CA  1 
ATOM   1528  C C   . TYR A 1 197 ? 104.413 152.541 142.151 1.00 33.89  ? 197 TYR A C   1 
ATOM   1529  O O   . TYR A 1 197 ? 103.454 152.998 141.522 1.00 33.89  ? 197 TYR A O   1 
ATOM   1530  C CB  . TYR A 1 197 ? 104.919 154.646 143.409 1.00 33.89  ? 197 TYR A CB  1 
ATOM   1531  C CG  . TYR A 1 197 ? 105.908 155.476 144.191 1.00 33.89  ? 197 TYR A CG  1 
ATOM   1532  C CD1 . TYR A 1 197 ? 107.243 155.113 144.274 1.00 33.89  ? 197 TYR A CD1 1 
ATOM   1533  C CD2 . TYR A 1 197 ? 105.499 156.623 144.856 1.00 33.89  ? 197 TYR A CD2 1 
ATOM   1534  C CE1 . TYR A 1 197 ? 108.145 155.873 144.990 1.00 33.89  ? 197 TYR A CE1 1 
ATOM   1535  C CE2 . TYR A 1 197 ? 106.393 157.388 145.575 1.00 33.89  ? 197 TYR A CE2 1 
ATOM   1536  C CZ  . TYR A 1 197 ? 107.714 157.009 145.640 1.00 33.89  ? 197 TYR A CZ  1 
ATOM   1537  O OH  . TYR A 1 197 ? 108.606 157.770 146.356 1.00 33.89  ? 197 TYR A OH  1 
ATOM   1538  N N   . CYS A 1 198 ? 104.547 151.243 142.426 1.00 35.34  ? 198 CYS A N   1 
ATOM   1539  C CA  . CYS A 1 198 ? 103.505 150.300 142.031 1.00 35.34  ? 198 CYS A CA  1 
ATOM   1540  C C   . CYS A 1 198 ? 102.293 150.396 142.952 1.00 35.34  ? 198 CYS A C   1 
ATOM   1541  O O   . CYS A 1 198 ? 101.152 150.451 142.480 1.00 35.34  ? 198 CYS A O   1 
ATOM   1542  C CB  . CYS A 1 198 ? 104.071 148.880 142.008 1.00 35.34  ? 198 CYS A CB  1 
ATOM   1543  S SG  . CYS A 1 198 ? 105.584 148.668 142.975 1.00 35.34  ? 198 CYS A SG  1 
ATOM   1544  N N   . THR A 1 199 ? 102.530 150.431 144.266 1.00 29.92  ? 199 THR A N   1 
ATOM   1545  C CA  . THR A 1 199 ? 101.502 150.522 145.318 1.00 29.92  ? 199 THR A CA  1 
ATOM   1546  C C   . THR A 1 199 ? 100.236 149.743 144.960 1.00 29.92  ? 199 THR A C   1 
ATOM   1547  O O   . THR A 1 199 ? 99.119  150.264 144.975 1.00 29.92  ? 199 THR A O   1 
ATOM   1548  C CB  . THR A 1 199 ? 101.181 151.980 145.674 1.00 29.92  ? 199 THR A CB  1 
ATOM   1549  O OG1 . THR A 1 199 ? 100.136 152.011 146.652 1.00 29.92  ? 199 THR A OG1 1 
ATOM   1550  C CG2 . THR A 1 199 ? 100.757 152.804 144.461 1.00 29.92  ? 199 THR A CG2 1 
ATOM   1551  N N   . LYS A 1 200 ? 100.422 148.463 144.655 1.00 31.37  ? 200 LYS A N   1 
ATOM   1552  C CA  . LYS A 1 200 ? 99.320  147.627 144.199 1.00 31.37  ? 200 LYS A CA  1 
ATOM   1553  C C   . LYS A 1 200 ? 98.355  147.311 145.336 1.00 31.37  ? 200 LYS A C   1 
ATOM   1554  O O   . LYS A 1 200 ? 98.746  147.176 146.498 1.00 31.37  ? 200 LYS A O   1 
ATOM   1555  C CB  . LYS A 1 200 ? 99.857  146.335 143.588 1.00 31.37  ? 200 LYS A CB  1 
ATOM   1556  C CG  . LYS A 1 200 ? 101.066 145.766 144.301 1.00 31.37  ? 200 LYS A CG  1 
ATOM   1557  C CD  . LYS A 1 200 ? 101.849 144.847 143.382 1.00 31.37  ? 200 LYS A CD  1 
ATOM   1558  C CE  . LYS A 1 200 ? 101.064 143.587 143.064 1.00 31.37  ? 200 LYS A CE  1 
ATOM   1559  N NZ  . LYS A 1 200 ? 101.769 142.717 142.083 1.00 31.37  ? 200 LYS A NZ  1 
ATOM   1560  N N   . HIS A 1 201 ? 97.077  147.187 144.982 1.00 34.43  ? 201 HIS A N   1 
ATOM   1561  C CA  . HIS A 1 201 ? 96.004  146.920 145.929 1.00 34.43  ? 201 HIS A CA  1 
ATOM   1562  C C   . HIS A 1 201 ? 95.510  145.487 145.784 1.00 34.43  ? 201 HIS A C   1 
ATOM   1563  O O   . HIS A 1 201 ? 95.331  144.991 144.668 1.00 34.43  ? 201 HIS A O   1 
ATOM   1564  C CB  . HIS A 1 201 ? 94.820  147.872 145.721 1.00 34.43  ? 201 HIS A CB  1 
ATOM   1565  C CG  . HIS A 1 201 ? 95.195  149.320 145.702 1.00 34.43  ? 201 HIS A CG  1 
ATOM   1566  N ND1 . HIS A 1 201 ? 95.916  149.891 144.676 1.00 34.43  ? 201 HIS A ND1 1 
ATOM   1567  C CD2 . HIS A 1 201 ? 94.932  150.318 146.577 1.00 34.43  ? 201 HIS A CD2 1 
ATOM   1568  C CE1 . HIS A 1 201 ? 96.090  151.177 144.925 1.00 34.43  ? 201 HIS A CE1 1 
ATOM   1569  N NE2 . HIS A 1 201 ? 95.503  151.461 146.073 1.00 34.43  ? 201 HIS A NE2 1 
ATOM   1570  N N   . TYR A 1 202 ? 95.287  144.833 146.915 1.00 35.38  ? 202 TYR A N   1 
ATOM   1571  C CA  . TYR A 1 202 ? 94.603  143.551 146.978 1.00 35.38  ? 202 TYR A CA  1 
ATOM   1572  C C   . TYR A 1 202 ? 93.260  143.744 147.673 1.00 35.38  ? 202 TYR A C   1 
ATOM   1573  O O   . TYR A 1 202 ? 92.858  144.864 148.001 1.00 35.38  ? 202 TYR A O   1 
ATOM   1574  C CB  . TYR A 1 202 ? 95.450  142.508 147.709 1.00 35.38  ? 202 TYR A CB  1 
ATOM   1575  C CG  . TYR A 1 202 ? 96.861  142.362 147.192 1.00 35.38  ? 202 TYR A CG  1 
ATOM   1576  C CD1 . TYR A 1 202 ? 97.150  142.504 145.845 1.00 35.38  ? 202 TYR A CD1 1 
ATOM   1577  C CD2 . TYR A 1 202 ? 97.904  142.071 148.057 1.00 35.38  ? 202 TYR A CD2 1 
ATOM   1578  C CE1 . TYR A 1 202 ? 98.442  142.367 145.377 1.00 35.38  ? 202 TYR A CE1 1 
ATOM   1579  C CE2 . TYR A 1 202 ? 99.195  141.932 147.599 1.00 35.38  ? 202 TYR A CE2 1 
ATOM   1580  C CZ  . TYR A 1 202 ? 99.460  142.081 146.260 1.00 35.38  ? 202 TYR A CZ  1 
ATOM   1581  O OH  . TYR A 1 202 ? 100.751 141.941 145.808 1.00 35.38  ? 202 TYR A OH  1 
ATOM   1582  N N   . ASN A 1 203 ? 92.558  142.636 147.902 1.00 38.06  ? 203 ASN A N   1 
ATOM   1583  C CA  . ASN A 1 203 ? 91.289  142.705 148.613 1.00 38.06  ? 203 ASN A CA  1 
ATOM   1584  C C   . ASN A 1 203 ? 91.457  142.757 150.126 1.00 38.06  ? 203 ASN A C   1 
ATOM   1585  O O   . ASN A 1 203 ? 90.475  143.011 150.831 1.00 38.06  ? 203 ASN A O   1 
ATOM   1586  C CB  . ASN A 1 203 ? 90.399  141.518 148.234 1.00 38.06  ? 203 ASN A CB  1 
ATOM   1587  C CG  . ASN A 1 203 ? 91.075  140.181 148.462 1.00 38.06  ? 203 ASN A CG  1 
ATOM   1588  O OD1 . ASN A 1 203 ? 92.163  140.109 149.031 1.00 38.06  ? 203 ASN A OD1 1 
ATOM   1589  N ND2 . ASN A 1 203 ? 90.427  139.110 148.020 1.00 38.06  ? 203 ASN A ND2 1 
ATOM   1590  N N   . THR A 1 204 ? 92.664  142.523 150.640 1.00 37.50  ? 204 THR A N   1 
ATOM   1591  C CA  . THR A 1 204 ? 92.915  142.573 152.074 1.00 37.50  ? 204 THR A CA  1 
ATOM   1592  C C   . THR A 1 204 ? 93.430  143.924 152.550 1.00 37.50  ? 204 THR A C   1 
ATOM   1593  O O   . THR A 1 204 ? 93.587  144.115 153.760 1.00 37.50  ? 204 THR A O   1 
ATOM   1594  C CB  . THR A 1 204 ? 93.919  141.491 152.479 1.00 37.50  ? 204 THR A CB  1 
ATOM   1595  O OG1 . THR A 1 204 ? 95.158  141.708 151.796 1.00 37.50  ? 204 THR A OG1 1 
ATOM   1596  C CG2 . THR A 1 204 ? 93.386  140.118 152.127 1.00 37.50  ? 204 THR A CG2 1 
ATOM   1597  N N   . GLY A 1 205 ? 93.696  144.853 151.648 1.00 37.49  ? 205 GLY A N   1 
ATOM   1598  C CA  . GLY A 1 205 ? 94.194  146.157 152.026 1.00 37.49  ? 205 GLY A CA  1 
ATOM   1599  C C   . GLY A 1 205 ? 94.972  146.777 150.884 1.00 37.49  ? 205 GLY A C   1 
ATOM   1600  O O   . GLY A 1 205 ? 94.889  146.329 149.746 1.00 37.49  ? 205 GLY A O   1 
ATOM   1601  N N   . LYS A 1 206 ? 95.729  147.818 151.219 1.00 35.00  ? 206 LYS A N   1 
ATOM   1602  C CA  . LYS A 1 206 ? 96.544  148.563 150.262 1.00 35.00  ? 206 LYS A CA  1 
ATOM   1603  C C   . LYS A 1 206 ? 98.006  148.398 150.664 1.00 35.00  ? 206 LYS A C   1 
ATOM   1604  O O   . LYS A 1 206 ? 98.533  149.178 151.460 1.00 35.00  ? 206 LYS A O   1 
ATOM   1605  C CB  . LYS A 1 206 ? 96.132  150.032 150.225 1.00 35.00  ? 206 LYS A CB  1 
ATOM   1606  C CG  . LYS A 1 206 ? 96.958  150.882 149.279 1.00 35.00  ? 206 LYS A CG  1 
ATOM   1607  C CD  . LYS A 1 206 ? 96.841  152.357 149.612 1.00 35.00  ? 206 LYS A CD  1 
ATOM   1608  C CE  . LYS A 1 206 ? 95.438  152.876 149.361 1.00 35.00  ? 206 LYS A CE  1 
ATOM   1609  N NZ  . LYS A 1 206 ? 95.355  154.347 149.574 1.00 35.00  ? 206 LYS A NZ  1 
ATOM   1610  N N   . PHE A 1 207 ? 98.663  147.382 150.114 1.00 32.59  ? 207 PHE A N   1 
ATOM   1611  C CA  . PHE A 1 207 ? 100.054 147.118 150.451 1.00 32.59  ? 207 PHE A CA  1 
ATOM   1612  C C   . PHE A 1 207 ? 100.976 148.039 149.667 1.00 32.59  ? 207 PHE A C   1 
ATOM   1613  O O   . PHE A 1 207 ? 100.771 148.278 148.474 1.00 32.59  ? 207 PHE A O   1 
ATOM   1614  C CB  . PHE A 1 207 ? 100.413 145.662 150.163 1.00 32.59  ? 207 PHE A CB  1 
ATOM   1615  C CG  . PHE A 1 207 ? 99.673  144.671 151.011 1.00 32.59  ? 207 PHE A CG  1 
ATOM   1616  C CD1 . PHE A 1 207 ? 98.966  145.078 152.126 1.00 32.59  ? 207 PHE A CD1 1 
ATOM   1617  C CD2 . PHE A 1 207 ? 99.692  143.325 150.693 1.00 32.59  ? 207 PHE A CD2 1 
ATOM   1618  C CE1 . PHE A 1 207 ? 98.286  144.164 152.902 1.00 32.59  ? 207 PHE A CE1 1 
ATOM   1619  C CE2 . PHE A 1 207 ? 99.015  142.407 151.464 1.00 32.59  ? 207 PHE A CE2 1 
ATOM   1620  C CZ  . PHE A 1 207 ? 98.312  142.826 152.570 1.00 32.59  ? 207 PHE A CZ  1 
ATOM   1621  N N   . THR A 1 208 ? 102.000 148.554 150.343 1.00 30.58  ? 208 THR A N   1 
ATOM   1622  C CA  . THR A 1 208 ? 102.965 149.422 149.691 1.00 30.58  ? 208 THR A CA  1 
ATOM   1623  C C   . THR A 1 208 ? 103.841 148.623 148.734 1.00 30.58  ? 208 THR A C   1 
ATOM   1624  O O   . THR A 1 208 ? 104.002 147.409 148.864 1.00 30.58  ? 208 THR A O   1 
ATOM   1625  C CB  . THR A 1 208 ? 103.840 150.129 150.720 1.00 30.58  ? 208 THR A CB  1 
ATOM   1626  O OG1 . THR A 1 208 ? 104.886 150.839 150.046 1.00 30.58  ? 208 THR A OG1 1 
ATOM   1627  C CG2 . THR A 1 208 ? 104.453 149.121 151.664 1.00 30.58  ? 208 THR A CG2 1 
ATOM   1628  N N   . CYS A 1 209 ? 104.412 149.324 147.759 1.00 30.24  ? 209 CYS A N   1 
ATOM   1629  C CA  . CYS A 1 209 ? 105.201 148.668 146.727 1.00 30.24  ? 209 CYS A CA  1 
ATOM   1630  C C   . CYS A 1 209 ? 106.166 149.672 146.118 1.00 30.24  ? 209 CYS A C   1 
ATOM   1631  O O   . CYS A 1 209 ? 105.882 150.870 146.060 1.00 30.24  ? 209 CYS A O   1 
ATOM   1632  C CB  . CYS A 1 209 ? 104.297 148.063 145.649 1.00 30.24  ? 209 CYS A CB  1 
ATOM   1633  S SG  . CYS A 1 209 ? 105.149 147.206 144.317 1.00 30.24  ? 209 CYS A SG  1 
ATOM   1634  N N   . ILE A 1 210 ? 107.311 149.167 145.668 1.00 29.36  ? 210 ILE A N   1 
ATOM   1635  C CA  . ILE A 1 210 ? 108.359 149.979 145.062 1.00 29.36  ? 210 ILE A CA  1 
ATOM   1636  C C   . ILE A 1 210 ? 108.928 149.211 143.880 1.00 29.36  ? 210 ILE A C   1 
ATOM   1637  O O   . ILE A 1 210 ? 109.220 148.017 143.996 1.00 29.36  ? 210 ILE A O   1 
ATOM   1638  C CB  . ILE A 1 210 ? 109.471 150.317 146.070 1.00 29.36  ? 210 ILE A CB  1 
ATOM   1639  C CG1 . ILE A 1 210 ? 108.982 151.359 147.069 1.00 29.36  ? 210 ILE A CG1 1 
ATOM   1640  C CG2 . ILE A 1 210 ? 110.693 150.826 145.357 1.00 29.36  ? 210 ILE A CG2 1 
ATOM   1641  C CD1 . ILE A 1 210 ? 108.559 152.648 146.431 1.00 29.36  ? 210 ILE A CD1 1 
ATOM   1642  N N   . GLU A 1 211 ? 109.095 149.888 142.748 1.00 30.99  ? 211 GLU A N   1 
ATOM   1643  C CA  . GLU A 1 211 ? 109.537 149.245 141.521 1.00 30.99  ? 211 GLU A CA  1 
ATOM   1644  C C   . GLU A 1 211 ? 110.664 150.047 140.892 1.00 30.99  ? 211 GLU A C   1 
ATOM   1645  O O   . GLU A 1 211 ? 110.618 151.280 140.865 1.00 30.99  ? 211 GLU A O   1 
ATOM   1646  C CB  . GLU A 1 211 ? 108.376 149.106 140.530 1.00 30.99  ? 211 GLU A CB  1 
ATOM   1647  C CG  . GLU A 1 211 ? 108.769 148.596 139.158 1.00 30.99  ? 211 GLU A CG  1 
ATOM   1648  C CD  . GLU A 1 211 ? 107.568 148.313 138.278 1.00 30.99  ? 211 GLU A CD  1 
ATOM   1649  O OE1 . GLU A 1 211 ? 106.428 148.499 138.753 1.00 30.99  ? 211 GLU A OE1 1 
ATOM   1650  O OE2 . GLU A 1 211 ? 107.762 147.902 137.115 1.00 30.99  ? 211 GLU A OE2 1 
ATOM   1651  N N   . VAL A 1 212 ? 111.677 149.344 140.390 1.00 29.36  ? 212 VAL A N   1 
ATOM   1652  C CA  . VAL A 1 212 ? 112.763 149.951 139.630 1.00 29.36  ? 212 VAL A CA  1 
ATOM   1653  C C   . VAL A 1 212 ? 112.894 149.206 138.311 1.00 29.36  ? 212 VAL A C   1 
ATOM   1654  O O   . VAL A 1 212 ? 112.954 147.972 138.293 1.00 29.36  ? 212 VAL A O   1 
ATOM   1655  C CB  . VAL A 1 212 ? 114.093 149.933 140.406 1.00 29.36  ? 212 VAL A CB  1 
ATOM   1656  C CG1 . VAL A 1 212 ? 114.261 148.626 141.124 1.00 29.36  ? 212 VAL A CG1 1 
ATOM   1657  C CG2 . VAL A 1 212 ? 115.259 150.168 139.468 1.00 29.36  ? 212 VAL A CG2 1 
ATOM   1658  N N   . ARG A 1 213 ? 112.932 149.952 137.212 1.00 33.88  ? 213 ARG A N   1 
ATOM   1659  C CA  . ARG A 1 213 ? 112.962 149.383 135.872 1.00 33.88  ? 213 ARG A CA  1 
ATOM   1660  C C   . ARG A 1 213 ? 114.375 149.452 135.312 1.00 33.88  ? 213 ARG A C   1 
ATOM   1661  O O   . ARG A 1 213 ? 115.031 150.494 135.397 1.00 33.88  ? 213 ARG A O   1 
ATOM   1662  C CB  . ARG A 1 213 ? 112.004 150.128 134.945 1.00 33.88  ? 213 ARG A CB  1 
ATOM   1663  C CG  . ARG A 1 213 ? 110.556 150.098 135.380 1.00 33.88  ? 213 ARG A CG  1 
ATOM   1664  C CD  . ARG A 1 213 ? 109.689 150.870 134.408 1.00 33.88  ? 213 ARG A CD  1 
ATOM   1665  N NE  . ARG A 1 213 ? 109.582 150.191 133.123 1.00 33.88  ? 213 ARG A NE  1 
ATOM   1666  C CZ  . ARG A 1 213 ? 108.444 149.982 132.478 1.00 33.88  ? 213 ARG A CZ  1 
ATOM   1667  N NH1 . ARG A 1 213 ? 107.284 150.379 132.975 1.00 33.88  ? 213 ARG A NH1 1 
ATOM   1668  N NH2 . ARG A 1 213 ? 108.469 149.358 131.303 1.00 33.88  ? 213 ARG A NH2 1 
ATOM   1669  N N   . PHE A 1 214 ? 114.835 148.347 134.736 1.00 34.21  ? 214 PHE A N   1 
ATOM   1670  C CA  . PHE A 1 214 ? 116.114 148.289 134.045 1.00 34.21  ? 214 PHE A CA  1 
ATOM   1671  C C   . PHE A 1 214 ? 115.862 148.278 132.546 1.00 34.21  ? 214 PHE A C   1 
ATOM   1672  O O   . PHE A 1 214 ? 115.047 147.489 132.058 1.00 34.21  ? 214 PHE A O   1 
ATOM   1673  C CB  . PHE A 1 214 ? 116.907 147.045 134.446 1.00 34.21  ? 214 PHE A CB  1 
ATOM   1674  C CG  . PHE A 1 214 ? 117.305 147.015 135.886 1.00 34.21  ? 214 PHE A CG  1 
ATOM   1675  C CD1 . PHE A 1 214 ? 117.503 148.187 136.587 1.00 34.21  ? 214 PHE A CD1 1 
ATOM   1676  C CD2 . PHE A 1 214 ? 117.481 145.812 136.541 1.00 34.21  ? 214 PHE A CD2 1 
ATOM   1677  C CE1 . PHE A 1 214 ? 117.869 148.157 137.915 1.00 34.21  ? 214 PHE A CE1 1 
ATOM   1678  C CE2 . PHE A 1 214 ? 117.846 145.778 137.866 1.00 34.21  ? 214 PHE A CE2 1 
ATOM   1679  C CZ  . PHE A 1 214 ? 118.039 146.952 138.554 1.00 34.21  ? 214 PHE A CZ  1 
ATOM   1680  N N   . HIS A 1 215 ? 116.555 149.147 131.819 1.00 37.41  ? 215 HIS A N   1 
ATOM   1681  C CA  . HIS A 1 215 ? 116.464 149.193 130.367 1.00 37.41  ? 215 HIS A CA  1 
ATOM   1682  C C   . HIS A 1 215 ? 117.643 148.426 129.784 1.00 37.41  ? 215 HIS A C   1 
ATOM   1683  O O   . HIS A 1 215 ? 118.799 148.813 129.983 1.00 37.41  ? 215 HIS A O   1 
ATOM   1684  C CB  . HIS A 1 215 ? 116.454 150.634 129.861 1.00 37.41  ? 215 HIS A CB  1 
ATOM   1685  C CG  . HIS A 1 215 ? 115.224 151.398 130.240 1.00 37.41  ? 215 HIS A CG  1 
ATOM   1686  N ND1 . HIS A 1 215 ? 113.990 151.146 129.682 1.00 37.41  ? 215 HIS A ND1 1 
ATOM   1687  C CD2 . HIS A 1 215 ? 115.041 152.416 131.114 1.00 37.41  ? 215 HIS A CD2 1 
ATOM   1688  C CE1 . HIS A 1 215 ? 113.098 151.972 130.200 1.00 37.41  ? 215 HIS A CE1 1 
ATOM   1689  N NE2 . HIS A 1 215 ? 113.710 152.753 131.071 1.00 37.41  ? 215 HIS A NE2 1 
ATOM   1690  N N   . LEU A 1 216 ? 117.351 147.346 129.070 1.00 37.29  ? 216 LEU A N   1 
ATOM   1691  C CA  . LEU A 1 216 ? 118.372 146.479 128.505 1.00 37.29  ? 216 LEU A CA  1 
ATOM   1692  C C   . LEU A 1 216 ? 118.312 146.528 126.986 1.00 37.29  ? 216 LEU A C   1 
ATOM   1693  O O   . LEU A 1 216 ? 117.228 146.591 126.399 1.00 37.29  ? 216 LEU A O   1 
ATOM   1694  C CB  . LEU A 1 216 ? 118.199 145.035 128.982 1.00 37.29  ? 216 LEU A CB  1 
ATOM   1695  C CG  . LEU A 1 216 ? 118.714 144.689 130.379 1.00 37.29  ? 216 LEU A CG  1 
ATOM   1696  C CD1 . LEU A 1 216 ? 117.776 145.208 131.450 1.00 37.29  ? 216 LEU A CD1 1 
ATOM   1697  C CD2 . LEU A 1 216 ? 118.903 143.191 130.520 1.00 37.29  ? 216 LEU A CD2 1 
ATOM   1698  N N   . GLU A 1 217 ? 119.481 146.502 126.355 1.00 44.65  ? 217 GLU A N   1 
ATOM   1699  C CA  . GLU A 1 217 ? 119.591 146.458 124.907 1.00 44.65  ? 217 GLU A CA  1 
ATOM   1700  C C   . GLU A 1 217 ? 120.519 145.319 124.521 1.00 44.65  ? 217 GLU A C   1 
ATOM   1701  O O   . GLU A 1 217 ? 121.545 145.099 125.170 1.00 44.65  ? 217 GLU A O   1 
ATOM   1702  C CB  . GLU A 1 217 ? 120.111 147.784 124.344 1.00 44.65  ? 217 GLU A CB  1 
ATOM   1703  C CG  . GLU A 1 217 ? 120.049 147.880 122.829 1.00 44.65  ? 217 GLU A CG  1 
ATOM   1704  C CD  . GLU A 1 217 ? 120.000 149.313 122.337 1.00 44.65  ? 217 GLU A CD  1 
ATOM   1705  O OE1 . GLU A 1 217 ? 120.089 150.234 123.176 1.00 44.65  ? 217 GLU A OE1 1 
ATOM   1706  O OE2 . GLU A 1 217 ? 119.870 149.520 121.112 1.00 44.65  ? 217 GLU A OE2 1 
ATOM   1707  N N   . ARG A 1 218 ? 120.156 144.596 123.467 1.00 41.66  ? 218 ARG A N   1 
ATOM   1708  C CA  . ARG A 1 218 ? 120.892 143.415 123.039 1.00 41.66  ? 218 ARG A CA  1 
ATOM   1709  C C   . ARG A 1 218 ? 121.873 143.780 121.935 1.00 41.66  ? 218 ARG A C   1 
ATOM   1710  O O   . ARG A 1 218 ? 121.496 144.429 120.954 1.00 41.66  ? 218 ARG A O   1 
ATOM   1711  C CB  . ARG A 1 218 ? 119.936 142.331 122.544 1.00 41.66  ? 218 ARG A CB  1 
ATOM   1712  C CG  . ARG A 1 218 ? 120.626 141.037 122.159 1.00 41.66  ? 218 ARG A CG  1 
ATOM   1713  C CD  . ARG A 1 218 ? 119.680 140.111 121.425 1.00 41.66  ? 218 ARG A CD  1 
ATOM   1714  N NE  . ARG A 1 218 ? 118.364 140.078 122.049 1.00 41.66  ? 218 ARG A NE  1 
ATOM   1715  C CZ  . ARG A 1 218 ? 117.966 139.150 122.906 1.00 41.66  ? 218 ARG A CZ  1 
ATOM   1716  N NH1 . ARG A 1 218 ? 118.759 138.155 123.264 1.00 41.66  ? 218 ARG A NH1 1 
ATOM   1717  N NH2 . ARG A 1 218 ? 116.740 139.222 123.416 1.00 41.66  ? 218 ARG A NH2 1 
ATOM   1718  N N   . GLN A 1 219 ? 123.106 143.281 122.062 1.00 51.33  ? 219 GLN A N   1 
ATOM   1719  C CA  . GLN A 1 219 ? 124.098 143.461 120.974 1.00 51.33  ? 219 GLN A CA  1 
ATOM   1720  C C   . GLN A 1 219 ? 123.838 142.331 119.977 1.00 51.33  ? 219 GLN A C   1 
ATOM   1721  O O   . GLN A 1 219 ? 123.701 141.185 120.433 1.00 51.33  ? 219 GLN A O   1 
ATOM   1722  C CB  . GLN A 1 219 ? 125.520 143.430 121.530 1.00 51.33  ? 219 GLN A CB  1 
ATOM   1723  C CG  . GLN A 1 219 ? 125.749 142.363 122.585 1.00 51.33  ? 219 GLN A CG  1 
ATOM   1724  C CD  . GLN A 1 219 ? 126.750 142.818 123.617 1.00 51.33  ? 219 GLN A CD  1 
ATOM   1725  O OE1 . GLN A 1 219 ? 127.499 143.767 123.404 1.00 51.33  ? 219 GLN A OE1 1 
ATOM   1726  N NE2 . GLN A 1 219 ? 126.771 142.138 124.752 1.00 51.33  ? 219 GLN A NE2 1 
ATOM   1727  N N   . MET A 1 220 ? 123.774 142.631 118.678 1.00 56.19  ? 220 MET A N   1 
ATOM   1728  C CA  . MET A 1 220 ? 123.376 141.596 117.688 1.00 56.19  ? 220 MET A CA  1 
ATOM   1729  C C   . MET A 1 220 ? 124.589 140.974 117.013 1.00 56.19  ? 220 MET A C   1 
ATOM   1730  O O   . MET A 1 220 ? 124.410 139.991 116.277 1.00 56.19  ? 220 MET A O   1 
ATOM   1731  C CB  . MET A 1 220 ? 122.521 142.238 116.593 1.00 56.19  ? 220 MET A CB  1 
ATOM   1732  C CG  . MET A 1 220 ? 121.615 141.257 115.872 1.00 56.19  ? 220 MET A CG  1 
ATOM   1733  S SD  . MET A 1 220 ? 122.259 140.753 114.257 1.00 56.19  ? 220 MET A SD  1 
ATOM   1734  C CE  . MET A 1 220 ? 123.332 142.138 113.883 1.00 56.19  ? 220 MET A CE  1 
ATOM   1735  N N   . GLY A 1 221 ? 125.783 141.484 117.278 1.00 52.65  ? 221 GLY A N   1 
ATOM   1736  C CA  . GLY A 1 221 ? 126.917 141.008 116.498 1.00 52.65  ? 221 GLY A CA  1 
ATOM   1737  C C   . GLY A 1 221 ? 127.098 139.501 116.534 1.00 52.65  ? 221 GLY A C   1 
ATOM   1738  O O   . GLY A 1 221 ? 127.425 138.882 115.517 1.00 52.65  ? 221 GLY A O   1 
ATOM   1739  N N   . TYR A 1 222 ? 126.901 138.887 117.704 1.00 52.48  ? 222 TYR A N   1 
ATOM   1740  C CA  . TYR A 1 222 ? 126.985 137.432 117.768 1.00 52.48  ? 222 TYR A CA  1 
ATOM   1741  C C   . TYR A 1 222 ? 125.939 136.789 116.874 1.00 52.48  ? 222 TYR A C   1 
ATOM   1742  O O   . TYR A 1 222 ? 126.225 135.810 116.175 1.00 52.48  ? 222 TYR A O   1 
ATOM   1743  C CB  . TYR A 1 222 ? 126.805 136.934 119.198 1.00 52.48  ? 222 TYR A CB  1 
ATOM   1744  C CG  . TYR A 1 222 ? 126.298 135.509 119.244 1.00 52.48  ? 222 TYR A CG  1 
ATOM   1745  C CD1 . TYR A 1 222 ? 127.129 134.446 118.920 1.00 52.48  ? 222 TYR A CD1 1 
ATOM   1746  C CD2 . TYR A 1 222 ? 124.984 135.229 119.587 1.00 52.48  ? 222 TYR A CD2 1 
ATOM   1747  C CE1 . TYR A 1 222 ? 126.671 133.147 118.950 1.00 52.48  ? 222 TYR A CE1 1 
ATOM   1748  C CE2 . TYR A 1 222 ? 124.517 133.932 119.618 1.00 52.48  ? 222 TYR A CE2 1 
ATOM   1749  C CZ  . TYR A 1 222 ? 125.365 132.895 119.300 1.00 52.48  ? 222 TYR A CZ  1 
ATOM   1750  O OH  . TYR A 1 222 ? 124.904 131.600 119.332 1.00 52.48  ? 222 TYR A OH  1 
ATOM   1751  N N   . TYR A 1 223 ? 124.713 137.312 116.905 1.00 54.27  ? 223 TYR A N   1 
ATOM   1752  C CA  . TYR A 1 223 ? 123.674 136.783 116.033 1.00 54.27  ? 223 TYR A CA  1 
ATOM   1753  C C   . TYR A 1 223 ? 124.031 137.001 114.573 1.00 54.27  ? 223 TYR A C   1 
ATOM   1754  O O   . TYR A 1 223 ? 123.808 136.117 113.742 1.00 54.27  ? 223 TYR A O   1 
ATOM   1755  C CB  . TYR A 1 223 ? 122.324 137.406 116.379 1.00 54.27  ? 223 TYR A CB  1 
ATOM   1756  C CG  . TYR A 1 223 ? 121.703 136.759 117.590 1.00 54.27  ? 223 TYR A CG  1 
ATOM   1757  C CD1 . TYR A 1 223 ? 121.079 135.525 117.492 1.00 54.27  ? 223 TYR A CD1 1 
ATOM   1758  C CD2 . TYR A 1 223 ? 121.773 137.360 118.836 1.00 54.27  ? 223 TYR A CD2 1 
ATOM   1759  C CE1 . TYR A 1 223 ? 120.522 134.919 118.597 1.00 54.27  ? 223 TYR A CE1 1 
ATOM   1760  C CE2 . TYR A 1 223 ? 121.220 136.761 119.948 1.00 54.27  ? 223 TYR A CE2 1 
ATOM   1761  C CZ  . TYR A 1 223 ? 120.596 135.540 119.822 1.00 54.27  ? 223 TYR A CZ  1 
ATOM   1762  O OH  . TYR A 1 223 ? 120.041 134.937 120.926 1.00 54.27  ? 223 TYR A OH  1 
ATOM   1763  N N   . LEU A 1 224 ? 124.612 138.159 114.246 1.00 52.71  ? 224 LEU A N   1 
ATOM   1764  C CA  . LEU A 1 224 ? 125.177 138.352 112.914 1.00 52.71  ? 224 LEU A CA  1 
ATOM   1765  C C   . LEU A 1 224 ? 126.063 137.175 112.530 1.00 52.71  ? 224 LEU A C   1 
ATOM   1766  O O   . LEU A 1 224 ? 125.709 136.377 111.654 1.00 52.71  ? 224 LEU A O   1 
ATOM   1767  C CB  . LEU A 1 224 ? 125.979 139.656 112.857 1.00 52.71  ? 224 LEU A CB  1 
ATOM   1768  C CG  . LEU A 1 224 ? 126.024 140.413 111.527 1.00 52.71  ? 224 LEU A CG  1 
ATOM   1769  C CD1 . LEU A 1 224 ? 126.322 141.892 111.731 1.00 52.71  ? 224 LEU A CD1 1 
ATOM   1770  C CD2 . LEU A 1 224 ? 127.056 139.794 110.600 1.00 52.71  ? 224 LEU A CD2 1 
ATOM   1771  N N   . ILE A 1 225 ? 127.166 137.001 113.263 1.00 53.23  ? 225 ILE A N   1 
ATOM   1772  C CA  . ILE A 1 225 ? 128.192 136.033 112.878 1.00 53.23  ? 225 ILE A CA  1 
ATOM   1773  C C   . ILE A 1 225 ? 127.614 134.627 112.802 1.00 53.23  ? 225 ILE A C   1 
ATOM   1774  O O   . ILE A 1 225 ? 127.899 133.874 111.863 1.00 53.23  ? 225 ILE A O   1 
ATOM   1775  C CB  . ILE A 1 225 ? 129.378 136.100 113.859 1.00 53.23  ? 225 ILE A CB  1 
ATOM   1776  C CG1 . ILE A 1 225 ? 130.177 137.388 113.654 1.00 53.23  ? 225 ILE A CG1 1 
ATOM   1777  C CG2 . ILE A 1 225 ? 130.271 134.881 113.707 1.00 53.23  ? 225 ILE A CG2 1 
ATOM   1778  C CD1 . ILE A 1 225 ? 131.348 137.529 114.602 1.00 53.23  ? 225 ILE A CD1 1 
ATOM   1779  N N   . GLN A 1 226 ? 126.795 134.248 113.780 1.00 59.02  ? 226 GLN A N   1 
ATOM   1780  C CA  . GLN A 1 226 ? 126.343 132.868 113.869 1.00 59.02  ? 226 GLN A CA  1 
ATOM   1781  C C   . GLN A 1 226 ? 125.122 132.567 113.008 1.00 59.02  ? 226 GLN A C   1 
ATOM   1782  O O   . GLN A 1 226 ? 124.850 131.391 112.742 1.00 59.02  ? 226 GLN A O   1 
ATOM   1783  C CB  . GLN A 1 226 ? 126.045 132.515 115.329 1.00 59.02  ? 226 GLN A CB  1 
ATOM   1784  C CG  . GLN A 1 226 ? 125.932 131.026 115.602 1.00 59.02  ? 226 GLN A CG  1 
ATOM   1785  C CD  . GLN A 1 226 ? 127.209 130.281 115.285 1.00 59.02  ? 226 GLN A CD  1 
ATOM   1786  O OE1 . GLN A 1 226 ? 128.307 130.826 115.403 1.00 59.02  ? 226 GLN A OE1 1 
ATOM   1787  N NE2 . GLN A 1 226 ? 127.073 129.028 114.868 1.00 59.02  ? 226 GLN A NE2 1 
ATOM   1788  N N   . MET A 1 227 ? 124.388 133.571 112.556 1.00 59.72  ? 227 MET A N   1 
ATOM   1789  C CA  . MET A 1 227 ? 123.131 133.215 111.917 1.00 59.72  ? 227 MET A CA  1 
ATOM   1790  C C   . MET A 1 227 ? 122.933 133.876 110.563 1.00 59.72  ? 227 MET A C   1 
ATOM   1791  O O   . MET A 1 227 ? 122.383 133.246 109.658 1.00 59.72  ? 227 MET A O   1 
ATOM   1792  C CB  . MET A 1 227 ? 121.981 133.589 112.858 1.00 59.72  ? 227 MET A CB  1 
ATOM   1793  C CG  . MET A 1 227 ? 121.782 132.589 113.979 1.00 59.72  ? 227 MET A CG  1 
ATOM   1794  S SD  . MET A 1 227 ? 121.010 131.039 113.502 1.00 59.72  ? 227 MET A SD  1 
ATOM   1795  C CE  . MET A 1 227 ? 119.999 130.758 114.949 1.00 59.72  ? 227 MET A CE  1 
ATOM   1796  N N   . TYR A 1 228 ? 123.364 135.128 110.398 1.00 53.16  ? 228 TYR A N   1 
ATOM   1797  C CA  . TYR A 1 228 ? 123.065 135.851 109.171 1.00 53.16  ? 228 TYR A CA  1 
ATOM   1798  C C   . TYR A 1 228 ? 124.096 135.592 108.083 1.00 53.16  ? 228 TYR A C   1 
ATOM   1799  O O   . TYR A 1 228 ? 123.735 135.433 106.913 1.00 53.16  ? 228 TYR A O   1 
ATOM   1800  C CB  . TYR A 1 228 ? 122.975 137.349 109.458 1.00 53.16  ? 228 TYR A CB  1 
ATOM   1801  C CG  . TYR A 1 228 ? 121.681 137.759 110.116 1.00 53.16  ? 228 TYR A CG  1 
ATOM   1802  C CD1 . TYR A 1 228 ? 120.633 136.864 110.242 1.00 53.16  ? 228 TYR A CD1 1 
ATOM   1803  C CD2 . TYR A 1 228 ? 121.509 139.043 110.610 1.00 53.16  ? 228 TYR A CD2 1 
ATOM   1804  C CE1 . TYR A 1 228 ? 119.449 137.235 110.840 1.00 53.16  ? 228 TYR A CE1 1 
ATOM   1805  C CE2 . TYR A 1 228 ? 120.327 139.423 111.211 1.00 53.16  ? 228 TYR A CE2 1 
ATOM   1806  C CZ  . TYR A 1 228 ? 119.301 138.515 111.323 1.00 53.16  ? 228 TYR A CZ  1 
ATOM   1807  O OH  . TYR A 1 228 ? 118.121 138.888 111.920 1.00 53.16  ? 228 TYR A OH  1 
ATOM   1808  N N   . ILE A 1 229 ? 125.377 135.558 108.447 1.00 53.57  ? 229 ILE A N   1 
ATOM   1809  C CA  . ILE A 1 229 ? 126.415 135.250 107.465 1.00 53.57  ? 229 ILE A CA  1 
ATOM   1810  C C   . ILE A 1 229 ? 126.251 133.854 106.872 1.00 53.57  ? 229 ILE A C   1 
ATOM   1811  O O   . ILE A 1 229 ? 126.346 133.718 105.642 1.00 53.57  ? 229 ILE A O   1 
ATOM   1812  C CB  . ILE A 1 229 ? 127.808 135.478 108.078 1.00 53.57  ? 229 ILE A CB  1 
ATOM   1813  C CG1 . ILE A 1 229 ? 127.967 136.941 108.491 1.00 53.57  ? 229 ILE A CG1 1 
ATOM   1814  C CG2 . ILE A 1 229 ? 128.895 135.086 107.094 1.00 53.57  ? 229 ILE A CG2 1 
ATOM   1815  C CD1 . ILE A 1 229 ? 127.768 137.919 107.359 1.00 53.57  ? 229 ILE A CD1 1 
ATOM   1816  N N   . PRO A 1 230 ? 126.032 132.788 107.657 1.00 53.26  ? 230 PRO A N   1 
ATOM   1817  C CA  . PRO A 1 230 ? 125.860 131.467 107.025 1.00 53.26  ? 230 PRO A CA  1 
ATOM   1818  C C   . PRO A 1 230 ? 124.694 131.398 106.054 1.00 53.26  ? 230 PRO A C   1 
ATOM   1819  O O   . PRO A 1 230 ? 124.815 130.768 104.995 1.00 53.26  ? 230 PRO A O   1 
ATOM   1820  C CB  . PRO A 1 230 ? 125.657 130.532 108.225 1.00 53.26  ? 230 PRO A CB  1 
ATOM   1821  C CG  . PRO A 1 230 ? 126.320 131.224 109.349 1.00 53.26  ? 230 PRO A CG  1 
ATOM   1822  C CD  . PRO A 1 230 ? 126.052 132.677 109.126 1.00 53.26  ? 230 PRO A CD  1 
ATOM   1823  N N   . SER A 1 231 ? 123.566 132.035 106.376 1.00 54.27  ? 231 SER A N   1 
ATOM   1824  C CA  . SER A 1 231 ? 122.429 132.019 105.462 1.00 54.27  ? 231 SER A CA  1 
ATOM   1825  C C   . SER A 1 231 ? 122.749 132.759 104.171 1.00 54.27  ? 231 SER A C   1 
ATOM   1826  O O   . SER A 1 231 ? 122.408 132.291 103.077 1.00 54.27  ? 231 SER A O   1 
ATOM   1827  C CB  . SER A 1 231 ? 121.202 132.624 106.140 1.00 54.27  ? 231 SER A CB  1 
ATOM   1828  O OG  . SER A 1 231 ? 120.810 131.847 107.257 1.00 54.27  ? 231 SER A OG  1 
ATOM   1829  N N   . LEU A 1 232 ? 123.406 133.915 104.279 1.00 55.43  ? 232 LEU A N   1 
ATOM   1830  C CA  . LEU A 1 232 ? 123.811 134.651 103.087 1.00 55.43  ? 232 LEU A CA  1 
ATOM   1831  C C   . LEU A 1 232 ? 124.778 133.832 102.242 1.00 55.43  ? 232 LEU A C   1 
ATOM   1832  O O   . LEU A 1 232 ? 124.680 133.818 101.010 1.00 55.43  ? 232 LEU A O   1 
ATOM   1833  C CB  . LEU A 1 232 ? 124.436 135.987 103.489 1.00 55.43  ? 232 LEU A CB  1 
ATOM   1834  C CG  . LEU A 1 232 ? 125.160 136.792 102.410 1.00 55.43  ? 232 LEU A CG  1 
ATOM   1835  C CD1 . LEU A 1 232 ? 124.743 138.251 102.469 1.00 55.43  ? 232 LEU A CD1 1 
ATOM   1836  C CD2 . LEU A 1 232 ? 126.666 136.665 102.568 1.00 55.43  ? 232 LEU A CD2 1 
ATOM   1837  N N   . LEU A 1 233 ? 125.718 133.141 102.889 1.00 58.53  ? 233 LEU A N   1 
ATOM   1838  C CA  . LEU A 1 233 ? 126.669 132.315 102.153 1.00 58.53  ? 233 LEU A CA  1 
ATOM   1839  C C   . LEU A 1 233 ? 125.968 131.168 101.439 1.00 58.53  ? 233 LEU A C   1 
ATOM   1840  O O   . LEU A 1 233 ? 126.289 130.859 100.288 1.00 58.53  ? 233 LEU A O   1 
ATOM   1841  C CB  . LEU A 1 233 ? 127.748 131.783 103.095 1.00 58.53  ? 233 LEU A CB  1 
ATOM   1842  C CG  . LEU A 1 233 ? 128.748 132.811 103.628 1.00 58.53  ? 233 LEU A CG  1 
ATOM   1843  C CD1 . LEU A 1 233 ? 129.878 132.126 104.383 1.00 58.53  ? 233 LEU A CD1 1 
ATOM   1844  C CD2 . LEU A 1 233 ? 129.295 133.670 102.500 1.00 58.53  ? 233 LEU A CD2 1 
ATOM   1845  N N   . ILE A 1 234 ? 125.003 130.528 102.101 1.00 55.54  ? 234 ILE A N   1 
ATOM   1846  C CA  . ILE A 1 234 ? 124.271 129.432 101.468 1.00 55.54  ? 234 ILE A CA  1 
ATOM   1847  C C   . ILE A 1 234 ? 123.469 129.942 100.276 1.00 55.54  ? 234 ILE A C   1 
ATOM   1848  O O   . ILE A 1 234 ? 123.434 129.311 99.209  1.00 55.54  ? 234 ILE A O   1 
ATOM   1849  C CB  . ILE A 1 234 ? 123.374 128.725 102.500 1.00 55.54  ? 234 ILE A CB  1 
ATOM   1850  C CG1 . ILE A 1 234 ? 124.224 127.887 103.455 1.00 55.54  ? 234 ILE A CG1 1 
ATOM   1851  C CG2 . ILE A 1 234 ? 122.342 127.854 101.809 1.00 55.54  ? 234 ILE A CG2 1 
ATOM   1852  C CD1 . ILE A 1 234 ? 125.024 126.810 102.767 1.00 55.54  ? 234 ILE A CD1 1 
ATOM   1853  N N   . VAL A 1 235 ? 122.816 131.094 100.433 1.00 58.83  ? 235 VAL A N   1 
ATOM   1854  C CA  . VAL A 1 235 ? 122.041 131.645 99.326  1.00 58.83  ? 235 VAL A CA  1 
ATOM   1855  C C   . VAL A 1 235 ? 122.955 131.989 98.155  1.00 58.83  ? 235 VAL A C   1 
ATOM   1856  O O   . VAL A 1 235 ? 122.654 131.668 97.000  1.00 58.83  ? 235 VAL A O   1 
ATOM   1857  C CB  . VAL A 1 235 ? 121.228 132.864 99.795  1.00 58.83  ? 235 VAL A CB  1 
ATOM   1858  C CG1 . VAL A 1 235 ? 120.891 133.754 98.620  1.00 58.83  ? 235 VAL A CG1 1 
ATOM   1859  C CG2 . VAL A 1 235 ? 119.965 132.411 100.500 1.00 58.83  ? 235 VAL A CG2 1 
ATOM   1860  N N   . ILE A 1 236 ? 124.095 132.628 98.433  1.00 63.21  ? 236 ILE A N   1 
ATOM   1861  C CA  . ILE A 1 236 ? 125.029 132.978 97.366  1.00 63.21  ? 236 ILE A CA  1 
ATOM   1862  C C   . ILE A 1 236 ? 125.605 131.719 96.724  1.00 63.21  ? 236 ILE A C   1 
ATOM   1863  O O   . ILE A 1 236 ? 125.924 131.704 95.527  1.00 63.21  ? 236 ILE A O   1 
ATOM   1864  C CB  . ILE A 1 236 ? 126.122 133.911 97.924  1.00 63.21  ? 236 ILE A CB  1 
ATOM   1865  C CG1 . ILE A 1 236 ? 125.605 135.349 97.989  1.00 63.21  ? 236 ILE A CG1 1 
ATOM   1866  C CG2 . ILE A 1 236 ? 127.367 133.881 97.064  1.00 63.21  ? 236 ILE A CG2 1 
ATOM   1867  C CD1 . ILE A 1 236 ? 124.997 135.838 96.693  1.00 63.21  ? 236 ILE A CD1 1 
ATOM   1868  N N   . LEU A 1 237 ? 125.731 130.638 97.494  1.00 63.19  ? 237 LEU A N   1 
ATOM   1869  C CA  . LEU A 1 237 ? 126.107 129.357 96.910  1.00 63.19  ? 237 LEU A CA  1 
ATOM   1870  C C   . LEU A 1 237 ? 125.050 128.868 95.932  1.00 63.19  ? 237 LEU A C   1 
ATOM   1871  O O   . LEU A 1 237 ? 125.379 128.324 94.874  1.00 63.19  ? 237 LEU A O   1 
ATOM   1872  C CB  . LEU A 1 237 ? 126.336 128.329 98.014  1.00 63.19  ? 237 LEU A CB  1 
ATOM   1873  C CG  . LEU A 1 237 ? 126.652 126.916 97.538  1.00 63.19  ? 237 LEU A CG  1 
ATOM   1874  C CD1 . LEU A 1 237 ? 127.834 126.357 98.306  1.00 63.19  ? 237 LEU A CD1 1 
ATOM   1875  C CD2 . LEU A 1 237 ? 125.423 126.045 97.710  1.00 63.19  ? 237 LEU A CD2 1 
ATOM   1876  N N   . SER A 1 238 ? 123.773 129.033 96.276  1.00 65.25  ? 238 SER A N   1 
ATOM   1877  C CA  . SER A 1 238 ? 122.715 128.701 95.323  1.00 65.25  ? 238 SER A CA  1 
ATOM   1878  C C   . SER A 1 238 ? 122.806 129.581 94.079  1.00 65.25  ? 238 SER A C   1 
ATOM   1879  O O   . SER A 1 238 ? 122.544 129.127 92.958  1.00 65.25  ? 238 SER A O   1 
ATOM   1880  C CB  . SER A 1 238 ? 121.345 128.843 95.981  1.00 65.25  ? 238 SER A CB  1 
ATOM   1881  O OG  . SER A 1 238 ? 120.309 128.645 95.035  1.00 65.25  ? 238 SER A OG  1 
ATOM   1882  N N   . TRP A 1 239 ? 123.167 130.849 94.268  1.00 73.10  ? 239 TRP A N   1 
ATOM   1883  C CA  . TRP A 1 239 ? 123.423 131.748 93.143  1.00 73.10  ? 239 TRP A CA  1 
ATOM   1884  C C   . TRP A 1 239 ? 124.485 131.173 92.211  1.00 73.10  ? 239 TRP A C   1 
ATOM   1885  O O   . TRP A 1 239 ? 124.290 131.090 90.992  1.00 73.10  ? 239 TRP A O   1 
ATOM   1886  C CB  . TRP A 1 239 ? 123.872 133.107 93.676  1.00 73.10  ? 239 TRP A CB  1 
ATOM   1887  C CG  . TRP A 1 239 ? 122.784 133.980 94.195  1.00 73.10  ? 239 TRP A CG  1 
ATOM   1888  C CD1 . TRP A 1 239 ? 121.946 133.718 95.234  1.00 73.10  ? 239 TRP A CD1 1 
ATOM   1889  C CD2 . TRP A 1 239 ? 122.493 135.313 93.776  1.00 73.10  ? 239 TRP A CD2 1 
ATOM   1890  N NE1 . TRP A 1 239 ? 121.107 134.779 95.449  1.00 73.10  ? 239 TRP A NE1 1 
ATOM   1891  C CE2 . TRP A 1 239 ? 121.428 135.777 94.569  1.00 73.10  ? 239 TRP A CE2 1 
ATOM   1892  C CE3 . TRP A 1 239 ? 123.014 136.151 92.788  1.00 73.10  ? 239 TRP A CE3 1 
ATOM   1893  C CZ2 . TRP A 1 239 ? 120.875 137.037 94.406  1.00 73.10  ? 239 TRP A CZ2 1 
ATOM   1894  C CZ3 . TRP A 1 239 ? 122.463 137.399 92.629  1.00 73.10  ? 239 TRP A CZ3 1 
ATOM   1895  C CH2 . TRP A 1 239 ? 121.409 137.832 93.435  1.00 73.10  ? 239 TRP A CH2 1 
ATOM   1896  N N   . VAL A 1 240 ? 125.624 130.775 92.780  1.00 71.85  ? 240 VAL A N   1 
ATOM   1897  C CA  . VAL A 1 240 ? 126.706 130.203 91.982  1.00 71.85  ? 240 VAL A CA  1 
ATOM   1898  C C   . VAL A 1 240 ? 126.248 128.910 91.318  1.00 71.85  ? 240 VAL A C   1 
ATOM   1899  O O   . VAL A 1 240 ? 126.619 128.611 90.176  1.00 71.85  ? 240 VAL A O   1 
ATOM   1900  C CB  . VAL A 1 240 ? 127.955 129.986 92.856  1.00 71.85  ? 240 VAL A CB  1 
ATOM   1901  C CG1 . VAL A 1 240 ? 129.033 129.249 92.079  1.00 71.85  ? 240 VAL A CG1 1 
ATOM   1902  C CG2 . VAL A 1 240 ? 128.479 131.320 93.363  1.00 71.85  ? 240 VAL A CG2 1 
ATOM   1903  N N   . SER A 1 241 ? 125.437 128.124 92.028  1.00 72.87  ? 241 SER A N   1 
ATOM   1904  C CA  . SER A 1 241 ? 124.806 126.952 91.433  1.00 72.87  ? 241 SER A CA  1 
ATOM   1905  C C   . SER A 1 241 ? 124.041 127.329 90.177  1.00 72.87  ? 241 SER A C   1 
ATOM   1906  O O   . SER A 1 241 ? 124.083 126.616 89.168  1.00 72.87  ? 241 SER A O   1 
ATOM   1907  C CB  . SER A 1 241 ? 123.860 126.309 92.444  1.00 72.87  ? 241 SER A CB  1 
ATOM   1908  O OG  . SER A 1 241 ? 124.396 126.369 93.753  1.00 72.87  ? 241 SER A OG  1 
ATOM   1909  N N   . PHE A 1 242 ? 123.322 128.447 90.232  1.00 77.43  ? 242 PHE A N   1 
ATOM   1910  C CA  . PHE A 1 242 ? 122.583 128.911 89.067  1.00 77.43  ? 242 PHE A CA  1 
ATOM   1911  C C   . PHE A 1 242 ? 123.525 129.385 87.966  1.00 77.43  ? 242 PHE A C   1 
ATOM   1912  O O   . PHE A 1 242 ? 123.195 129.269 86.780  1.00 77.43  ? 242 PHE A O   1 
ATOM   1913  C CB  . PHE A 1 242 ? 121.586 129.996 89.509  1.00 77.43  ? 242 PHE A CB  1 
ATOM   1914  C CG  . PHE A 1 242 ? 120.991 130.812 88.385  1.00 77.43  ? 242 PHE A CG  1 
ATOM   1915  C CD1 . PHE A 1 242 ? 121.747 131.719 87.653  1.00 77.43  ? 242 PHE A CD1 1 
ATOM   1916  C CD2 . PHE A 1 242 ? 119.665 130.633 88.041  1.00 77.43  ? 242 PHE A CD2 1 
ATOM   1917  C CE1 . PHE A 1 242 ? 121.187 132.435 86.627  1.00 77.43  ? 242 PHE A CE1 1 
ATOM   1918  C CE2 . PHE A 1 242 ? 119.102 131.347 87.013  1.00 77.43  ? 242 PHE A CE2 1 
ATOM   1919  C CZ  . PHE A 1 242 ? 119.865 132.252 86.306  1.00 77.43  ? 242 PHE A CZ  1 
ATOM   1920  N N   . TRP A 1 243 ? 124.702 129.901 88.334  1.00 80.65  ? 243 TRP A N   1 
ATOM   1921  C CA  . TRP A 1 243 ? 125.586 130.518 87.345  1.00 80.65  ? 243 TRP A CA  1 
ATOM   1922  C C   . TRP A 1 243 ? 126.003 129.534 86.255  1.00 80.65  ? 243 TRP A C   1 
ATOM   1923  O O   . TRP A 1 243 ? 126.013 129.884 85.069  1.00 80.65  ? 243 TRP A O   1 
ATOM   1924  C CB  . TRP A 1 243 ? 126.818 131.102 88.035  1.00 80.65  ? 243 TRP A CB  1 
ATOM   1925  C CG  . TRP A 1 243 ? 126.820 132.598 88.090  1.00 80.65  ? 243 TRP A CG  1 
ATOM   1926  C CD1 . TRP A 1 243 ? 126.446 133.381 89.141  1.00 80.65  ? 243 TRP A CD1 1 
ATOM   1927  C CD2 . TRP A 1 243 ? 127.217 133.493 87.044  1.00 80.65  ? 243 TRP A CD2 1 
ATOM   1928  N NE1 . TRP A 1 243 ? 126.584 134.709 88.815  1.00 80.65  ? 243 TRP A NE1 1 
ATOM   1929  C CE2 . TRP A 1 243 ? 127.056 134.804 87.533  1.00 80.65  ? 243 TRP A CE2 1 
ATOM   1930  C CE3 . TRP A 1 243 ? 127.693 133.313 85.742  1.00 80.65  ? 243 TRP A CE3 1 
ATOM   1931  C CZ2 . TRP A 1 243 ? 127.354 135.929 86.767  1.00 80.65  ? 243 TRP A CZ2 1 
ATOM   1932  C CZ3 . TRP A 1 243 ? 127.987 134.430 84.984  1.00 80.65  ? 243 TRP A CZ3 1 
ATOM   1933  C CH2 . TRP A 1 243 ? 127.817 135.721 85.498  1.00 80.65  ? 243 TRP A CH2 1 
ATOM   1934  N N   . ILE A 1 244 ? 126.355 128.305 86.632  1.00 83.95  ? 244 ILE A N   1 
ATOM   1935  C CA  . ILE A 1 244 ? 126.759 127.309 85.646  1.00 83.95  ? 244 ILE A CA  1 
ATOM   1936  C C   . ILE A 1 244 ? 125.556 126.906 84.802  1.00 83.95  ? 244 ILE A C   1 
ATOM   1937  O O   . ILE A 1 244 ? 124.428 126.801 85.304  1.00 83.95  ? 244 ILE A O   1 
ATOM   1938  C CB  . ILE A 1 244 ? 127.409 126.101 86.349  1.00 83.95  ? 244 ILE A CB  1 
ATOM   1939  C CG1 . ILE A 1 244 ? 127.217 124.810 85.549  1.00 83.95  ? 244 ILE A CG1 1 
ATOM   1940  C CG2 . ILE A 1 244 ? 126.888 125.958 87.771  1.00 83.95  ? 244 ILE A CG2 1 
ATOM   1941  C CD1 . ILE A 1 244 ? 127.750 123.580 86.250  1.00 83.95  ? 244 ILE A CD1 1 
ATOM   1942  N N   . ASN A 1 245 ? 125.789 126.687 83.507  1.00 93.71  ? 245 ASN A N   1 
ATOM   1943  C CA  . ASN A 1 245 ? 124.711 126.468 82.551  1.00 93.71  ? 245 ASN A CA  1 
ATOM   1944  C C   . ASN A 1 245 ? 123.983 125.153 82.839  1.00 93.71  ? 245 ASN A C   1 
ATOM   1945  O O   . ASN A 1 245 ? 124.312 124.410 83.768  1.00 93.71  ? 245 ASN A O   1 
ATOM   1946  C CB  . ASN A 1 245 ? 125.255 126.486 81.124  1.00 93.71  ? 245 ASN A CB  1 
ATOM   1947  C CG  . ASN A 1 245 ? 126.046 125.239 80.781  1.00 93.71  ? 245 ASN A CG  1 
ATOM   1948  O OD1 . ASN A 1 245 ? 126.629 124.595 81.654  1.00 93.71  ? 245 ASN A OD1 1 
ATOM   1949  N ND2 . ASN A 1 245 ? 126.078 124.896 79.499  1.00 93.71  ? 245 ASN A ND2 1 
ATOM   1950  N N   . MET A 1 246 ? 122.977 124.866 82.015  1.00 95.10  ? 246 MET A N   1 
ATOM   1951  C CA  . MET A 1 246 ? 122.061 123.756 82.236  1.00 95.10  ? 246 MET A CA  1 
ATOM   1952  C C   . MET A 1 246 ? 122.502 122.463 81.560  1.00 95.10  ? 246 MET A C   1 
ATOM   1953  O O   . MET A 1 246 ? 121.738 121.492 81.565  1.00 95.10  ? 246 MET A O   1 
ATOM   1954  C CB  . MET A 1 246 ? 120.646 124.113 81.758  1.00 95.10  ? 246 MET A CB  1 
ATOM   1955  C CG  . MET A 1 246 ? 120.439 124.202 80.238  1.00 95.10  ? 246 MET A CG  1 
ATOM   1956  S SD  . MET A 1 246 ? 121.748 124.887 79.199  1.00 95.10  ? 246 MET A SD  1 
ATOM   1957  C CE  . MET A 1 246 ? 121.819 126.584 79.776  1.00 95.10  ? 246 MET A CE  1 
ATOM   1958  N N   . ASP A 1 247 ? 123.699 122.425 80.971  1.00 96.61  ? 247 ASP A N   1 
ATOM   1959  C CA  . ASP A 1 247 ? 124.148 121.203 80.307  1.00 96.61  ? 247 ASP A CA  1 
ATOM   1960  C C   . ASP A 1 247 ? 124.263 120.042 81.289  1.00 96.61  ? 247 ASP A C   1 
ATOM   1961  O O   . ASP A 1 247 ? 123.846 118.919 80.986  1.00 96.61  ? 247 ASP A O   1 
ATOM   1962  C CB  . ASP A 1 247 ? 125.482 121.441 79.601  1.00 96.61  ? 247 ASP A CB  1 
ATOM   1963  C CG  . ASP A 1 247 ? 125.319 122.161 78.279  1.00 96.61  ? 247 ASP A CG  1 
ATOM   1964  O OD1 . ASP A 1 247 ? 124.164 122.421 77.880  1.00 96.61  ? 247 ASP A OD1 1 
ATOM   1965  O OD2 . ASP A 1 247 ? 126.347 122.464 77.637  1.00 96.61  ? 247 ASP A OD2 1 
ATOM   1966  N N   . ALA A 1 248 ? 124.823 120.292 82.472  1.00 81.99  ? 248 ALA A N   1 
ATOM   1967  C CA  . ALA A 1 248 ? 124.961 119.256 83.494  1.00 81.99  ? 248 ALA A CA  1 
ATOM   1968  C C   . ALA A 1 248 ? 123.784 119.342 84.466  1.00 81.99  ? 248 ALA A C   1 
ATOM   1969  O O   . ALA A 1 248 ? 123.903 119.770 85.615  1.00 81.99  ? 248 ALA A O   1 
ATOM   1970  C CB  . ALA A 1 248 ? 126.298 119.388 84.211  1.00 81.99  ? 248 ALA A CB  1 
ATOM   1971  N N   . ALA A 1 249 ? 122.623 118.920 83.969  1.00 78.50  ? 249 ALA A N   1 
ATOM   1972  C CA  . ALA A 1 249 ? 121.399 118.993 84.764  1.00 78.50  ? 249 ALA A CA  1 
ATOM   1973  C C   . ALA A 1 249 ? 121.466 118.200 86.065  1.00 78.50  ? 249 ALA A C   1 
ATOM   1974  O O   . ALA A 1 249 ? 121.077 118.749 87.111  1.00 78.50  ? 249 ALA A O   1 
ATOM   1975  C CB  . ALA A 1 249 ? 120.207 118.552 83.908  1.00 78.50  ? 249 ALA A CB  1 
ATOM   1976  N N   . PRO A 1 250 ? 121.911 116.933 86.088  1.00 73.90  ? 250 PRO A N   1 
ATOM   1977  C CA  . PRO A 1 250 ? 121.878 116.189 87.361  1.00 73.90  ? 250 PRO A CA  1 
ATOM   1978  C C   . PRO A 1 250 ? 122.719 116.811 88.461  1.00 73.90  ? 250 PRO A C   1 
ATOM   1979  O O   . PRO A 1 250 ? 122.269 116.877 89.611  1.00 73.90  ? 250 PRO A O   1 
ATOM   1980  C CB  . PRO A 1 250 ? 122.397 114.799 86.967  1.00 73.90  ? 250 PRO A CB  1 
ATOM   1981  C CG  . PRO A 1 250 ? 123.180 115.024 85.728  1.00 73.90  ? 250 PRO A CG  1 
ATOM   1982  C CD  . PRO A 1 250 ? 122.437 116.093 84.997  1.00 73.90  ? 250 PRO A CD  1 
ATOM   1983  N N   . ALA A 1 251 ? 123.928 117.280 88.142  1.00 73.98  ? 251 ALA A N   1 
ATOM   1984  C CA  . ALA A 1 251 ? 124.782 117.871 89.167  1.00 73.98  ? 251 ALA A CA  1 
ATOM   1985  C C   . ALA A 1 251 ? 124.153 119.132 89.748  1.00 73.98  ? 251 ALA A C   1 
ATOM   1986  O O   . ALA A 1 251 ? 124.100 119.307 90.973  1.00 73.98  ? 251 ALA A O   1 
ATOM   1987  C CB  . ALA A 1 251 ? 126.164 118.174 88.587  1.00 73.98  ? 251 ALA A CB  1 
ATOM   1988  N N   . ARG A 1 252 ? 123.662 120.020 88.878  1.00 78.01  ? 252 ARG A N   1 
ATOM   1989  C CA  . ARG A 1 252 ? 123.052 121.257 89.350  1.00 78.01  ? 252 ARG A CA  1 
ATOM   1990  C C   . ARG A 1 252 ? 121.805 120.978 90.176  1.00 78.01  ? 252 ARG A C   1 
ATOM   1991  O O   . ARG A 1 252 ? 121.582 121.614 91.213  1.00 78.01  ? 252 ARG A O   1 
ATOM   1992  C CB  . ARG A 1 252 ? 122.724 122.167 88.167  1.00 78.01  ? 252 ARG A CB  1 
ATOM   1993  C CG  . ARG A 1 252 ? 123.925 122.470 87.296  1.00 78.01  ? 252 ARG A CG  1 
ATOM   1994  C CD  . ARG A 1 252 ? 124.054 123.952 86.994  1.00 78.01  ? 252 ARG A CD  1 
ATOM   1995  N NE  . ARG A 1 252 ? 122.930 124.488 86.237  1.00 78.01  ? 252 ARG A NE  1 
ATOM   1996  C CZ  . ARG A 1 252 ? 122.062 125.371 86.709  1.00 78.01  ? 252 ARG A CZ  1 
ATOM   1997  N NH1 . ARG A 1 252 ? 122.129 125.808 87.956  1.00 78.01  ? 252 ARG A NH1 1 
ATOM   1998  N NH2 . ARG A 1 252 ? 121.107 125.834 85.908  1.00 78.01  ? 252 ARG A NH2 1 
ATOM   1999  N N   . VAL A 1 253 ? 120.984 120.020 89.744  1.00 78.22  ? 253 VAL A N   1 
ATOM   2000  C CA  . VAL A 1 253 ? 119.757 119.743 90.482  1.00 78.22  ? 253 VAL A CA  1 
ATOM   2001  C C   . VAL A 1 253 ? 120.072 119.100 91.832  1.00 78.22  ? 253 VAL A C   1 
ATOM   2002  O O   . VAL A 1 253 ? 119.424 119.406 92.840  1.00 78.22  ? 253 VAL A O   1 
ATOM   2003  C CB  . VAL A 1 253 ? 118.792 118.898 89.628  1.00 78.22  ? 253 VAL A CB  1 
ATOM   2004  C CG1 . VAL A 1 253 ? 119.063 117.403 89.758  1.00 78.22  ? 253 VAL A CG1 1 
ATOM   2005  C CG2 . VAL A 1 253 ? 117.351 119.236 89.976  1.00 78.22  ? 253 VAL A CG2 1 
ATOM   2006  N N   . ALA A 1 254 ? 121.085 118.228 91.888  1.00 76.17  ? 254 ALA A N   1 
ATOM   2007  C CA  . ALA A 1 254 ? 121.470 117.627 93.162  1.00 76.17  ? 254 ALA A CA  1 
ATOM   2008  C C   . ALA A 1 254 ? 122.010 118.677 94.121  1.00 76.17  ? 254 ALA A C   1 
ATOM   2009  O O   . ALA A 1 254 ? 121.708 118.652 95.323  1.00 76.17  ? 254 ALA A O   1 
ATOM   2010  C CB  . ALA A 1 254 ? 122.505 116.526 92.933  1.00 76.17  ? 254 ALA A CB  1 
ATOM   2011  N N   . LEU A 1 255 ? 122.816 119.604 93.605  1.00 69.52  ? 255 LEU A N   1 
ATOM   2012  C CA  . LEU A 1 255 ? 123.291 120.713 94.421  1.00 69.52  ? 255 LEU A CA  1 
ATOM   2013  C C   . LEU A 1 255 ? 122.132 121.578 94.907  1.00 69.52  ? 255 LEU A C   1 
ATOM   2014  O O   . LEU A 1 255 ? 122.146 122.069 96.043  1.00 69.52  ? 255 LEU A O   1 
ATOM   2015  C CB  . LEU A 1 255 ? 124.319 121.511 93.620  1.00 69.52  ? 255 LEU A CB  1 
ATOM   2016  C CG  . LEU A 1 255 ? 124.529 123.014 93.703  1.00 69.52  ? 255 LEU A CG  1 
ATOM   2017  C CD1 . LEU A 1 255 ? 125.116 123.424 95.023  1.00 69.52  ? 255 LEU A CD1 1 
ATOM   2018  C CD2 . LEU A 1 255 ? 125.498 123.353 92.590  1.00 69.52  ? 255 LEU A CD2 1 
ATOM   2019  N N   . GLY A 1 256 ? 121.103 121.747 94.075  1.00 64.96  ? 256 GLY A N   1 
ATOM   2020  C CA  . GLY A 1 256 ? 119.912 122.450 94.529  1.00 64.96  ? 256 GLY A CA  1 
ATOM   2021  C C   . GLY A 1 256 ? 119.224 121.750 95.688  1.00 64.96  ? 256 GLY A C   1 
ATOM   2022  O O   . GLY A 1 256 ? 118.863 122.382 96.688  1.00 64.96  ? 256 GLY A O   1 
ATOM   2023  N N   . ILE A 1 257 ? 119.035 120.431 95.571  1.00 71.68  ? 257 ILE A N   1 
ATOM   2024  C CA  . ILE A 1 257 ? 118.412 119.680 96.664  1.00 71.68  ? 257 ILE A CA  1 
ATOM   2025  C C   . ILE A 1 257 ? 119.225 119.821 97.942  1.00 71.68  ? 257 ILE A C   1 
ATOM   2026  O O   . ILE A 1 257 ? 118.674 120.061 99.023  1.00 71.68  ? 257 ILE A O   1 
ATOM   2027  C CB  . ILE A 1 257 ? 118.220 118.195 96.301  1.00 71.68  ? 257 ILE A CB  1 
ATOM   2028  C CG1 . ILE A 1 257 ? 117.807 118.005 94.847  1.00 71.68  ? 257 ILE A CG1 1 
ATOM   2029  C CG2 . ILE A 1 257 ? 117.225 117.539 97.246  1.00 71.68  ? 257 ILE A CG2 1 
ATOM   2030  C CD1 . ILE A 1 257 ? 118.197 116.654 94.295  1.00 71.68  ? 257 ILE A CD1 1 
ATOM   2031  N N   . THR A 1 258 ? 120.546 119.656 97.845  1.00 67.96  ? 258 THR A N   1 
ATOM   2032  C CA  . THR A 1 258 ? 121.348 119.672 99.064  1.00 67.96  ? 258 THR A CA  1 
ATOM   2033  C C   . THR A 1 258 ? 121.385 121.061 99.696  1.00 67.96  ? 258 THR A C   1 
ATOM   2034  O O   . THR A 1 258 ? 121.346 121.179 100.930 1.00 67.96  ? 258 THR A O   1 
ATOM   2035  C CB  . THR A 1 258 ? 122.758 119.137 98.788  1.00 67.96  ? 258 THR A CB  1 
ATOM   2036  O OG1 . THR A 1 258 ? 123.412 118.856 100.031 1.00 67.96  ? 258 THR A OG1 1 
ATOM   2037  C CG2 . THR A 1 258 ? 123.592 120.123 97.997  1.00 67.96  ? 258 THR A CG2 1 
ATOM   2038  N N   . THR A 1 259 ? 121.410 122.125 98.883  1.00 62.88  ? 259 THR A N   1 
ATOM   2039  C CA  . THR A 1 259 ? 121.380 123.462 99.461  1.00 62.88  ? 259 THR A CA  1 
ATOM   2040  C C   . THR A 1 259 ? 120.033 123.743 100.117 1.00 62.88  ? 259 THR A C   1 
ATOM   2041  O O   . THR A 1 259 ? 119.979 124.360 101.188 1.00 62.88  ? 259 THR A O   1 
ATOM   2042  C CB  . THR A 1 259 ? 121.732 124.515 98.402  1.00 62.88  ? 259 THR A CB  1 
ATOM   2043  O OG1 . THR A 1 259 ? 122.249 125.684 99.048  1.00 62.88  ? 259 THR A OG1 1 
ATOM   2044  C CG2 . THR A 1 259 ? 120.532 124.911 97.556  1.00 62.88  ? 259 THR A CG2 1 
ATOM   2045  N N   . VAL A 1 260 ? 118.938 123.251 99.525  1.00 65.53  ? 260 VAL A N   1 
ATOM   2046  C CA  . VAL A 1 260 ? 117.626 123.448 100.138 1.00 65.53  ? 260 VAL A CA  1 
ATOM   2047  C C   . VAL A 1 260 ? 117.541 122.698 101.461 1.00 65.53  ? 260 VAL A C   1 
ATOM   2048  O O   . VAL A 1 260 ? 117.005 123.212 102.452 1.00 65.53  ? 260 VAL A O   1 
ATOM   2049  C CB  . VAL A 1 260 ? 116.511 123.024 99.164  1.00 65.53  ? 260 VAL A CB  1 
ATOM   2050  C CG1 . VAL A 1 260 ? 115.275 122.569 99.924  1.00 65.53  ? 260 VAL A CG1 1 
ATOM   2051  C CG2 . VAL A 1 260 ? 116.169 124.169 98.230  1.00 65.53  ? 260 VAL A CG2 1 
ATOM   2052  N N   . LEU A 1 261 ? 118.073 121.474 101.501 1.00 68.71  ? 261 LEU A N   1 
ATOM   2053  C CA  . LEU A 1 261 ? 118.038 120.689 102.732 1.00 68.71  ? 261 LEU A CA  1 
ATOM   2054  C C   . LEU A 1 261 ? 118.827 121.369 103.843 1.00 68.71  ? 261 LEU A C   1 
ATOM   2055  O O   . LEU A 1 261 ? 118.358 121.472 104.983 1.00 68.71  ? 261 LEU A O   1 
ATOM   2056  C CB  . LEU A 1 261 ? 118.587 119.288 102.480 1.00 68.71  ? 261 LEU A CB  1 
ATOM   2057  C CG  . LEU A 1 261 ? 117.790 118.412 101.524 1.00 68.71  ? 261 LEU A CG  1 
ATOM   2058  C CD1 . LEU A 1 261 ? 118.534 117.114 101.304 1.00 68.71  ? 261 LEU A CD1 1 
ATOM   2059  C CD2 . LEU A 1 261 ? 116.400 118.166 102.073 1.00 68.71  ? 261 LEU A CD2 1 
ATOM   2060  N N   . THR A 1 262 ? 120.040 121.831 103.533 1.00 66.76  ? 262 THR A N   1 
ATOM   2061  C CA  . THR A 1 262 ? 120.819 122.506 104.563 1.00 66.76  ? 262 THR A CA  1 
ATOM   2062  C C   . THR A 1 262 ? 120.162 123.805 105.004 1.00 66.76  ? 262 THR A C   1 
ATOM   2063  O O   . THR A 1 262 ? 120.196 124.141 106.193 1.00 66.76  ? 262 THR A O   1 
ATOM   2064  C CB  . THR A 1 262 ? 122.241 122.761 104.080 1.00 66.76  ? 262 THR A CB  1 
ATOM   2065  O OG1 . THR A 1 262 ? 122.206 123.394 102.795 1.00 66.76  ? 262 THR A OG1 1 
ATOM   2066  C CG2 . THR A 1 262 ? 122.995 121.452 103.998 1.00 66.76  ? 262 THR A CG2 1 
ATOM   2067  N N   . MET A 1 263 ? 119.550 124.544 104.078 1.00 62.14  ? 263 MET A N   1 
ATOM   2068  C CA  . MET A 1 263 ? 118.898 125.784 104.474 1.00 62.14  ? 263 MET A CA  1 
ATOM   2069  C C   . MET A 1 263 ? 117.700 125.513 105.378 1.00 62.14  ? 263 MET A C   1 
ATOM   2070  O O   . MET A 1 263 ? 117.479 126.234 106.359 1.00 62.14  ? 263 MET A O   1 
ATOM   2071  C CB  . MET A 1 263 ? 118.481 126.572 103.239 1.00 62.14  ? 263 MET A CB  1 
ATOM   2072  C CG  . MET A 1 263 ? 117.780 127.854 103.571 1.00 62.14  ? 263 MET A CG  1 
ATOM   2073  S SD  . MET A 1 263 ? 119.012 128.965 104.260 1.00 62.14  ? 263 MET A SD  1 
ATOM   2074  C CE  . MET A 1 263 ? 118.460 130.518 103.594 1.00 62.14  ? 263 MET A CE  1 
ATOM   2075  N N   . THR A 1 264 ? 116.922 124.469 105.078 1.00 66.88  ? 264 THR A N   1 
ATOM   2076  C CA  . THR A 1 264 ? 115.774 124.168 105.929 1.00 66.88  ? 264 THR A CA  1 
ATOM   2077  C C   . THR A 1 264 ? 116.208 123.621 107.286 1.00 66.88  ? 264 THR A C   1 
ATOM   2078  O O   . THR A 1 264 ? 115.545 123.888 108.294 1.00 66.88  ? 264 THR A O   1 
ATOM   2079  C CB  . THR A 1 264 ? 114.808 123.207 105.225 1.00 66.88  ? 264 THR A CB  1 
ATOM   2080  O OG1 . THR A 1 264 ? 113.525 123.271 105.861 1.00 66.88  ? 264 THR A OG1 1 
ATOM   2081  C CG2 . THR A 1 264 ? 115.304 121.773 105.269 1.00 66.88  ? 264 THR A CG2 1 
ATOM   2082  N N   . THR A 1 265 ? 117.328 122.891 107.350 1.00 64.44  ? 265 THR A N   1 
ATOM   2083  C CA  . THR A 1 265 ? 117.807 122.460 108.661 1.00 64.44  ? 265 THR A CA  1 
ATOM   2084  C C   . THR A 1 265 ? 118.352 123.640 109.460 1.00 64.44  ? 265 THR A C   1 
ATOM   2085  O O   . THR A 1 265 ? 118.194 123.684 110.688 1.00 64.44  ? 265 THR A O   1 
ATOM   2086  C CB  . THR A 1 265 ? 118.849 121.342 108.519 1.00 64.44  ? 265 THR A CB  1 
ATOM   2087  O OG1 . THR A 1 265 ? 118.822 120.514 109.689 1.00 64.44  ? 265 THR A OG1 1 
ATOM   2088  C CG2 . THR A 1 265 ? 120.257 121.889 108.345 1.00 64.44  ? 265 THR A CG2 1 
ATOM   2089  N N   . GLN A 1 266 ? 118.951 124.624 108.781 1.00 63.65  ? 266 GLN A N   1 
ATOM   2090  C CA  . GLN A 1 266 ? 119.354 125.851 109.457 1.00 63.65  ? 266 GLN A CA  1 
ATOM   2091  C C   . GLN A 1 266 ? 118.144 126.588 110.011 1.00 63.65  ? 266 GLN A C   1 
ATOM   2092  O O   . GLN A 1 266 ? 118.175 127.092 111.139 1.00 63.65  ? 266 GLN A O   1 
ATOM   2093  C CB  . GLN A 1 266 ? 120.130 126.746 108.493 1.00 63.65  ? 266 GLN A CB  1 
ATOM   2094  C CG  . GLN A 1 266 ? 120.658 128.021 109.116 1.00 63.65  ? 266 GLN A CG  1 
ATOM   2095  C CD  . GLN A 1 266 ? 121.976 127.813 109.826 1.00 63.65  ? 266 GLN A CD  1 
ATOM   2096  O OE1 . GLN A 1 266 ? 123.005 127.583 109.194 1.00 63.65  ? 266 GLN A OE1 1 
ATOM   2097  N NE2 . GLN A 1 266 ? 121.953 127.895 111.151 1.00 63.65  ? 266 GLN A NE2 1 
ATOM   2098  N N   . SER A 1 267 ? 117.065 126.659 109.227 1.00 66.60  ? 267 SER A N   1 
ATOM   2099  C CA  . SER A 1 267 ? 115.843 127.302 109.701 1.00 66.60  ? 267 SER A CA  1 
ATOM   2100  C C   . SER A 1 267 ? 115.264 126.570 110.905 1.00 66.60  ? 267 SER A C   1 
ATOM   2101  O O   . SER A 1 267 ? 114.815 127.201 111.873 1.00 66.60  ? 267 SER A O   1 
ATOM   2102  C CB  . SER A 1 267 ? 114.815 127.365 108.573 1.00 66.60  ? 267 SER A CB  1 
ATOM   2103  O OG  . SER A 1 267 ? 114.333 126.072 108.253 1.00 66.60  ? 267 SER A OG  1 
ATOM   2104  N N   . SER A 1 268 ? 115.256 125.235 110.856 1.00 68.66  ? 268 SER A N   1 
ATOM   2105  C CA  . SER A 1 268 ? 114.745 124.454 111.978 1.00 68.66  ? 268 SER A CA  1 
ATOM   2106  C C   . SER A 1 268 ? 115.557 124.709 113.239 1.00 68.66  ? 268 SER A C   1 
ATOM   2107  O O   . SER A 1 268 ? 114.990 124.910 114.319 1.00 68.66  ? 268 SER A O   1 
ATOM   2108  C CB  . SER A 1 268 ? 114.752 122.966 111.631 1.00 68.66  ? 268 SER A CB  1 
ATOM   2109  O OG  . SER A 1 268 ? 116.072 122.451 111.626 1.00 68.66  ? 268 SER A OG  1 
ATOM   2110  N N   . GLY A 1 269 ? 116.886 124.714 113.122 1.00 70.45  ? 269 GLY A N   1 
ATOM   2111  C CA  . GLY A 1 269 ? 117.714 125.016 114.279 1.00 70.45  ? 269 GLY A CA  1 
ATOM   2112  C C   . GLY A 1 269 ? 117.484 126.419 114.808 1.00 70.45  ? 269 GLY A C   1 
ATOM   2113  O O   . GLY A 1 269 ? 117.408 126.633 116.024 1.00 70.45  ? 269 GLY A O   1 
ATOM   2114  N N   . SER A 1 270 ? 117.354 127.392 113.902 1.00 67.86  ? 270 SER A N   1 
ATOM   2115  C CA  . SER A 1 270 ? 117.138 128.775 114.314 1.00 67.86  ? 270 SER A CA  1 
ATOM   2116  C C   . SER A 1 270 ? 115.840 128.925 115.091 1.00 67.86  ? 270 SER A C   1 
ATOM   2117  O O   . SER A 1 270 ? 115.797 129.612 116.118 1.00 67.86  ? 270 SER A O   1 
ATOM   2118  C CB  . SER A 1 270 ? 117.128 129.688 113.090 1.00 67.86  ? 270 SER A CB  1 
ATOM   2119  O OG  . SER A 1 270 ? 116.068 129.348 112.215 1.00 67.86  ? 270 SER A OG  1 
ATOM   2120  N N   . ARG A 1 271 ? 114.767 128.295 114.615 1.00 74.11  ? 271 ARG A N   1 
ATOM   2121  C CA  . ARG A 1 271 ? 113.492 128.392 115.314 1.00 74.11  ? 271 ARG A CA  1 
ATOM   2122  C C   . ARG A 1 271 ? 113.441 127.534 116.573 1.00 74.11  ? 271 ARG A C   1 
ATOM   2123  O O   . ARG A 1 271 ? 112.678 127.855 117.491 1.00 74.11  ? 271 ARG A O   1 
ATOM   2124  C CB  . ARG A 1 271 ? 112.343 128.014 114.376 1.00 74.11  ? 271 ARG A CB  1 
ATOM   2125  C CG  . ARG A 1 271 ? 112.021 129.085 113.345 1.00 74.11  ? 271 ARG A CG  1 
ATOM   2126  C CD  . ARG A 1 271 ? 110.885 128.659 112.433 1.00 74.11  ? 271 ARG A CD  1 
ATOM   2127  N NE  . ARG A 1 271 ? 111.222 127.480 111.644 1.00 74.11  ? 271 ARG A NE  1 
ATOM   2128  C CZ  . ARG A 1 271 ? 111.667 127.515 110.396 1.00 74.11  ? 271 ARG A CZ  1 
ATOM   2129  N NH1 . ARG A 1 271 ? 111.845 128.660 109.758 1.00 74.11  ? 271 ARG A NH1 1 
ATOM   2130  N NH2 . ARG A 1 271 ? 111.937 126.373 109.771 1.00 74.11  ? 271 ARG A NH2 1 
ATOM   2131  N N   . ALA A 1 272 ? 114.231 126.460 116.645 1.00 77.66  ? 272 ALA A N   1 
ATOM   2132  C CA  . ALA A 1 272 ? 114.222 125.609 117.827 1.00 77.66  ? 272 ALA A CA  1 
ATOM   2133  C C   . ALA A 1 272 ? 115.139 126.115 118.932 1.00 77.66  ? 272 ALA A C   1 
ATOM   2134  O O   . ALA A 1 272 ? 115.004 125.675 120.079 1.00 77.66  ? 272 ALA A O   1 
ATOM   2135  C CB  . ALA A 1 272 ? 114.616 124.180 117.447 1.00 77.66  ? 272 ALA A CB  1 
ATOM   2136  N N   . SER A 1 273 ? 116.062 127.027 118.622 1.00 73.65  ? 273 SER A N   1 
ATOM   2137  C CA  . SER A 1 273 ? 116.942 127.561 119.654 1.00 73.65  ? 273 SER A CA  1 
ATOM   2138  C C   . SER A 1 273 ? 116.235 128.528 120.598 1.00 73.65  ? 273 SER A C   1 
ATOM   2139  O O   . SER A 1 273 ? 116.827 128.922 121.609 1.00 73.65  ? 273 SER A O   1 
ATOM   2140  C CB  . SER A 1 273 ? 118.145 128.252 119.008 1.00 73.65  ? 273 SER A CB  1 
ATOM   2141  O OG  . SER A 1 273 ? 118.986 128.838 119.986 1.00 73.65  ? 273 SER A OG  1 
ATOM   2142  N N   . LEU A 1 274 ? 114.994 128.906 120.308 1.00 72.96  ? 274 LEU A N   1 
ATOM   2143  C CA  . LEU A 1 274 ? 114.289 129.953 121.028 1.00 72.96  ? 274 LEU A CA  1 
ATOM   2144  C C   . LEU A 1 274 ? 112.938 129.443 121.514 1.00 72.96  ? 274 LEU A C   1 
ATOM   2145  O O   . LEU A 1 274 ? 112.335 128.570 120.880 1.00 72.96  ? 274 LEU A O   1 
ATOM   2146  C CB  . LEU A 1 274 ? 114.113 131.180 120.116 1.00 72.96  ? 274 LEU A CB  1 
ATOM   2147  C CG  . LEU A 1 274 ? 113.734 132.587 120.587 1.00 72.96  ? 274 LEU A CG  1 
ATOM   2148  C CD1 . LEU A 1 274 ? 114.120 133.574 119.505 1.00 72.96  ? 274 LEU A CD1 1 
ATOM   2149  C CD2 . LEU A 1 274 ? 112.242 132.708 120.859 1.00 72.96  ? 274 LEU A CD2 1 
ATOM   2150  N N   . PRO A 1 275 ? 112.443 129.963 122.656 1.00 69.19  ? 275 PRO A N   1 
ATOM   2151  C CA  . PRO A 1 275 ? 111.141 129.516 123.179 1.00 69.19  ? 275 PRO A CA  1 
ATOM   2152  C C   . PRO A 1 275 ? 109.963 129.783 122.251 1.00 69.19  ? 275 PRO A C   1 
ATOM   2153  O O   . PRO A 1 275 ? 110.121 130.355 121.170 1.00 69.19  ? 275 PRO A O   1 
ATOM   2154  C CB  . PRO A 1 275 ? 111.000 130.308 124.487 1.00 69.19  ? 275 PRO A CB  1 
ATOM   2155  C CG  . PRO A 1 275 ? 111.980 131.432 124.371 1.00 69.19  ? 275 PRO A CG  1 
ATOM   2156  C CD  . PRO A 1 275 ? 113.125 130.849 123.612 1.00 69.19  ? 275 PRO A CD  1 
ATOM   2157  N N   . LYS A 1 276 ? 108.771 129.380 122.680 1.00 59.86  ? 276 LYS A N   1 
ATOM   2158  C CA  . LYS A 1 276 ? 107.602 129.356 121.816 1.00 59.86  ? 276 LYS A CA  1 
ATOM   2159  C C   . LYS A 1 276 ? 106.785 130.624 122.025 1.00 59.86  ? 276 LYS A C   1 
ATOM   2160  O O   . LYS A 1 276 ? 106.433 130.958 123.158 1.00 59.86  ? 276 LYS A O   1 
ATOM   2161  C CB  . LYS A 1 276 ? 106.762 128.122 122.134 1.00 59.86  ? 276 LYS A CB  1 
ATOM   2162  C CG  . LYS A 1 276 ? 107.587 126.856 122.270 1.00 59.86  ? 276 LYS A CG  1 
ATOM   2163  C CD  . LYS A 1 276 ? 107.752 126.136 120.954 1.00 59.86  ? 276 LYS A CD  1 
ATOM   2164  C CE  . LYS A 1 276 ? 107.882 124.646 121.218 1.00 59.86  ? 276 LYS A CE  1 
ATOM   2165  N NZ  . LYS A 1 276 ? 108.452 124.424 122.572 1.00 59.86  ? 276 LYS A NZ  1 
ATOM   2166  N N   . VAL A 1 277 ? 106.472 131.318 120.936 1.00 53.73  ? 277 VAL A N   1 
ATOM   2167  C CA  . VAL A 1 277 ? 105.685 132.543 120.998 1.00 53.73  ? 277 VAL A CA  1 
ATOM   2168  C C   . VAL A 1 277 ? 104.702 132.556 119.837 1.00 53.73  ? 277 VAL A C   1 
ATOM   2169  O O   . VAL A 1 277 ? 105.022 132.102 118.734 1.00 53.73  ? 277 VAL A O   1 
ATOM   2170  C CB  . VAL A 1 277 ? 106.591 133.790 120.986 1.00 53.73  ? 277 VAL A CB  1 
ATOM   2171  C CG1 . VAL A 1 277 ? 107.092 134.092 122.391 1.00 53.73  ? 277 VAL A CG1 1 
ATOM   2172  C CG2 . VAL A 1 277 ? 107.757 133.565 120.063 1.00 53.73  ? 277 VAL A CG2 1 
ATOM   2173  N N   . SER A 1 278 ? 103.498 133.071 120.092 1.00 47.97  ? 278 SER A N   1 
ATOM   2174  C CA  . SER A 1 278 ? 102.443 133.025 119.085 1.00 47.97  ? 278 SER A CA  1 
ATOM   2175  C C   . SER A 1 278 ? 102.785 133.877 117.870 1.00 47.97  ? 278 SER A C   1 
ATOM   2176  O O   . SER A 1 278 ? 102.558 133.458 116.730 1.00 47.97  ? 278 SER A O   1 
ATOM   2177  C CB  . SER A 1 278 ? 101.115 133.473 119.692 1.00 47.97  ? 278 SER A CB  1 
ATOM   2178  O OG  . SER A 1 278 ? 100.106 133.542 118.698 1.00 47.97  ? 278 SER A OG  1 
ATOM   2179  N N   . TYR A 1 279 ? 103.328 135.071 118.085 1.00 46.77  ? 279 TYR A N   1 
ATOM   2180  C CA  . TYR A 1 279 ? 103.548 136.011 116.994 1.00 46.77  ? 279 TYR A CA  1 
ATOM   2181  C C   . TYR A 1 279 ? 104.814 135.634 116.225 1.00 46.77  ? 279 TYR A C   1 
ATOM   2182  O O   . TYR A 1 279 ? 105.385 134.555 116.404 1.00 46.77  ? 279 TYR A O   1 
ATOM   2183  C CB  . TYR A 1 279 ? 103.602 137.439 117.529 1.00 46.77  ? 279 TYR A CB  1 
ATOM   2184  C CG  . TYR A 1 279 ? 104.612 137.647 118.628 1.00 46.77  ? 279 TYR A CG  1 
ATOM   2185  C CD1 . TYR A 1 279 ? 104.284 137.405 119.952 1.00 46.77  ? 279 TYR A CD1 1 
ATOM   2186  C CD2 . TYR A 1 279 ? 105.896 138.079 118.341 1.00 46.77  ? 279 TYR A CD2 1 
ATOM   2187  C CE1 . TYR A 1 279 ? 105.204 137.592 120.957 1.00 46.77  ? 279 TYR A CE1 1 
ATOM   2188  C CE2 . TYR A 1 279 ? 106.825 138.268 119.339 1.00 46.77  ? 279 TYR A CE2 1 
ATOM   2189  C CZ  . TYR A 1 279 ? 106.474 138.023 120.645 1.00 46.77  ? 279 TYR A CZ  1 
ATOM   2190  O OH  . TYR A 1 279 ? 107.397 138.211 121.647 1.00 46.77  ? 279 TYR A OH  1 
ATOM   2191  N N   . VAL A 1 280 ? 105.261 136.527 115.347 1.00 44.85  ? 280 VAL A N   1 
ATOM   2192  C CA  . VAL A 1 280 ? 106.419 136.282 114.497 1.00 44.85  ? 280 VAL A CA  1 
ATOM   2193  C C   . VAL A 1 280 ? 107.547 137.213 114.919 1.00 44.85  ? 280 VAL A C   1 
ATOM   2194  O O   . VAL A 1 280 ? 107.317 138.319 115.422 1.00 44.85  ? 280 VAL A O   1 
ATOM   2195  C CB  . VAL A 1 280 ? 106.073 136.467 113.002 1.00 44.85  ? 280 VAL A CB  1 
ATOM   2196  C CG1 . VAL A 1 280 ? 105.878 137.938 112.667 1.00 44.85  ? 280 VAL A CG1 1 
ATOM   2197  C CG2 . VAL A 1 280 ? 107.139 135.837 112.119 1.00 44.85  ? 280 VAL A CG2 1 
ATOM   2198  N N   . LYS A 1 281 ? 108.778 136.756 114.715 1.00 42.08  ? 281 LYS A N   1 
ATOM   2199  C CA  . LYS A 1 281 ? 109.971 137.488 115.111 1.00 42.08  ? 281 LYS A CA  1 
ATOM   2200  C C   . LYS A 1 281 ? 110.836 137.774 113.889 1.00 42.08  ? 281 LYS A C   1 
ATOM   2201  O O   . LYS A 1 281 ? 110.666 137.180 112.822 1.00 42.08  ? 281 LYS A O   1 
ATOM   2202  C CB  . LYS A 1 281 ? 110.765 136.708 116.165 1.00 42.08  ? 281 LYS A CB  1 
ATOM   2203  C CG  . LYS A 1 281 ? 111.114 135.295 115.754 1.00 42.08  ? 281 LYS A CG  1 
ATOM   2204  C CD  . LYS A 1 281 ? 111.716 134.525 116.911 1.00 42.08  ? 281 LYS A CD  1 
ATOM   2205  C CE  . LYS A 1 281 ? 110.669 134.197 117.948 1.00 42.08  ? 281 LYS A CE  1 
ATOM   2206  N NZ  . LYS A 1 281 ? 109.666 133.252 117.395 1.00 42.08  ? 281 LYS A NZ  1 
ATOM   2207  N N   . ALA A 1 282 ? 111.780 138.703 114.064 1.00 43.58  ? 282 ALA A N   1 
ATOM   2208  C CA  . ALA A 1 282 ? 112.574 139.183 112.936 1.00 43.58  ? 282 ALA A CA  1 
ATOM   2209  C C   . ALA A 1 282 ? 113.433 138.078 112.336 1.00 43.58  ? 282 ALA A C   1 
ATOM   2210  O O   . ALA A 1 282 ? 113.535 137.960 111.108 1.00 43.58  ? 282 ALA A O   1 
ATOM   2211  C CB  . ALA A 1 282 ? 113.447 140.357 113.375 1.00 43.58  ? 282 ALA A CB  1 
ATOM   2212  N N   . ILE A 1 283 ? 114.068 137.265 113.181 1.00 41.74  ? 283 ILE A N   1 
ATOM   2213  C CA  . ILE A 1 283 ? 114.907 136.185 112.669 1.00 41.74  ? 283 ILE A CA  1 
ATOM   2214  C C   . ILE A 1 283 ? 114.067 135.202 111.868 1.00 41.74  ? 283 ILE A C   1 
ATOM   2215  O O   . ILE A 1 283 ? 114.505 134.684 110.832 1.00 41.74  ? 283 ILE A O   1 
ATOM   2216  C CB  . ILE A 1 283 ? 115.655 135.491 113.823 1.00 41.74  ? 283 ILE A CB  1 
ATOM   2217  C CG1 . ILE A 1 283 ? 116.471 134.309 113.305 1.00 41.74  ? 283 ILE A CG1 1 
ATOM   2218  C CG2 . ILE A 1 283 ? 114.689 135.029 114.889 1.00 41.74  ? 283 ILE A CG2 1 
ATOM   2219  C CD1 . ILE A 1 283 ? 117.640 134.712 112.458 1.00 41.74  ? 283 ILE A CD1 1 
ATOM   2220  N N   . ASP A 1 284 ? 112.839 134.944 112.323 1.00 43.28  ? 284 ASP A N   1 
ATOM   2221  C CA  . ASP A 1 284 ? 111.948 134.057 111.587 1.00 43.28  ? 284 ASP A CA  1 
ATOM   2222  C C   . ASP A 1 284 ? 111.619 134.624 110.213 1.00 43.28  ? 284 ASP A C   1 
ATOM   2223  O O   . ASP A 1 284 ? 111.628 133.894 109.217 1.00 43.28  ? 284 ASP A O   1 
ATOM   2224  C CB  . ASP A 1 284 ? 110.669 133.819 112.387 1.00 43.28  ? 284 ASP A CB  1 
ATOM   2225  C CG  . ASP A 1 284 ? 109.784 132.762 111.766 1.00 43.28  ? 284 ASP A CG  1 
ATOM   2226  O OD1 . ASP A 1 284 ? 110.286 131.980 110.932 1.00 43.28  ? 284 ASP A OD1 1 
ATOM   2227  O OD2 . ASP A 1 284 ? 108.585 132.714 112.110 1.00 43.28  ? 284 ASP A OD2 1 
ATOM   2228  N N   . ILE A 1 285 ? 111.335 135.926 110.140 1.00 42.29  ? 285 ILE A N   1 
ATOM   2229  C CA  . ILE A 1 285 ? 111.010 136.547 108.859 1.00 42.29  ? 285 ILE A CA  1 
ATOM   2230  C C   . ILE A 1 285 ? 112.202 136.470 107.915 1.00 42.29  ? 285 ILE A C   1 
ATOM   2231  O O   . ILE A 1 285 ? 112.061 136.124 106.736 1.00 42.29  ? 285 ILE A O   1 
ATOM   2232  C CB  . ILE A 1 285 ? 110.545 137.999 109.070 1.00 42.29  ? 285 ILE A CB  1 
ATOM   2233  C CG1 . ILE A 1 285 ? 109.033 138.047 109.284 1.00 42.29  ? 285 ILE A CG1 1 
ATOM   2234  C CG2 . ILE A 1 285 ? 110.932 138.870 107.886 1.00 42.29  ? 285 ILE A CG2 1 
ATOM   2235  C CD1 . ILE A 1 285 ? 108.497 139.440 109.511 1.00 42.29  ? 285 ILE A CD1 1 
ATOM   2236  N N   . TRP A 1 286 ? 113.396 136.785 108.422 1.00 45.87  ? 286 TRP A N   1 
ATOM   2237  C CA  . TRP A 1 286 ? 114.586 136.736 107.580 1.00 45.87  ? 286 TRP A CA  1 
ATOM   2238  C C   . TRP A 1 286 ? 114.829 135.328 107.053 1.00 45.87  ? 286 TRP A C   1 
ATOM   2239  O O   . TRP A 1 286 ? 115.080 135.132 105.856 1.00 45.87  ? 286 TRP A O   1 
ATOM   2240  C CB  . TRP A 1 286 ? 115.803 137.233 108.358 1.00 45.87  ? 286 TRP A CB  1 
ATOM   2241  C CG  . TRP A 1 286 ? 117.098 137.027 107.638 1.00 45.87  ? 286 TRP A CG  1 
ATOM   2242  C CD1 . TRP A 1 286 ? 117.859 135.896 107.626 1.00 45.87  ? 286 TRP A CD1 1 
ATOM   2243  C CD2 . TRP A 1 286 ? 117.787 137.980 106.823 1.00 45.87  ? 286 TRP A CD2 1 
ATOM   2244  N NE1 . TRP A 1 286 ? 118.976 136.084 106.854 1.00 45.87  ? 286 TRP A NE1 1 
ATOM   2245  C CE2 . TRP A 1 286 ? 118.956 137.357 106.350 1.00 45.87  ? 286 TRP A CE2 1 
ATOM   2246  C CE3 . TRP A 1 286 ? 117.528 139.301 106.447 1.00 45.87  ? 286 TRP A CE3 1 
ATOM   2247  C CZ2 . TRP A 1 286 ? 119.865 138.007 105.522 1.00 45.87  ? 286 TRP A CZ2 1 
ATOM   2248  C CZ3 . TRP A 1 286 ? 118.431 139.944 105.625 1.00 45.87  ? 286 TRP A CZ3 1 
ATOM   2249  C CH2 . TRP A 1 286 ? 119.585 139.297 105.171 1.00 45.87  ? 286 TRP A CH2 1 
ATOM   2250  N N   . MET A 1 287 ? 114.760 134.330 107.937 1.00 46.18  ? 287 MET A N   1 
ATOM   2251  C CA  . MET A 1 287 ? 115.020 132.960 107.513 1.00 46.18  ? 287 MET A CA  1 
ATOM   2252  C C   . MET A 1 287 ? 113.968 132.483 106.522 1.00 46.18  ? 287 MET A C   1 
ATOM   2253  O O   . MET A 1 287 ? 114.293 131.808 105.538 1.00 46.18  ? 287 MET A O   1 
ATOM   2254  C CB  . MET A 1 287 ? 115.080 132.037 108.727 1.00 46.18  ? 287 MET A CB  1 
ATOM   2255  C CG  . MET A 1 287 ? 115.840 130.754 108.474 1.00 46.18  ? 287 MET A CG  1 
ATOM   2256  S SD  . MET A 1 287 ? 117.625 130.993 108.432 1.00 46.18  ? 287 MET A SD  1 
ATOM   2257  C CE  . MET A 1 287 ? 117.839 132.214 109.722 1.00 46.18  ? 287 MET A CE  1 
ATOM   2258  N N   . ALA A 1 288 ? 112.700 132.830 106.757 1.00 49.13  ? 288 ALA A N   1 
ATOM   2259  C CA  . ALA A 1 288 ? 111.645 132.434 105.834 1.00 49.13  ? 288 ALA A CA  1 
ATOM   2260  C C   . ALA A 1 288 ? 111.844 133.064 104.463 1.00 49.13  ? 288 ALA A C   1 
ATOM   2261  O O   . ALA A 1 288 ? 111.682 132.394 103.438 1.00 49.13  ? 288 ALA A O   1 
ATOM   2262  C CB  . ALA A 1 288 ? 110.279 132.811 106.405 1.00 49.13  ? 288 ALA A CB  1 
ATOM   2263  N N   . VAL A 1 289 ? 112.205 134.348 104.419 1.00 49.49  ? 289 VAL A N   1 
ATOM   2264  C CA  . VAL A 1 289 ? 112.385 135.004 103.129 1.00 49.49  ? 289 VAL A CA  1 
ATOM   2265  C C   . VAL A 1 289 ? 113.579 134.415 102.390 1.00 49.49  ? 289 VAL A C   1 
ATOM   2266  O O   . VAL A 1 289 ? 113.531 134.213 101.172 1.00 49.49  ? 289 VAL A O   1 
ATOM   2267  C CB  . VAL A 1 289 ? 112.522 136.526 103.302 1.00 49.49  ? 289 VAL A CB  1 
ATOM   2268  C CG1 . VAL A 1 289 ? 112.902 137.161 101.980 1.00 49.49  ? 289 VAL A CG1 1 
ATOM   2269  C CG2 . VAL A 1 289 ? 111.218 137.115 103.802 1.00 49.49  ? 289 VAL A CG2 1 
ATOM   2270  N N   . CYS A 1 290 ? 114.670 134.131 103.102 1.00 51.53  ? 290 CYS A N   1 
ATOM   2271  C CA  . CYS A 1 290 ? 115.830 133.550 102.433 1.00 51.53  ? 290 CYS A CA  1 
ATOM   2272  C C   . CYS A 1 290 ? 115.535 132.137 101.930 1.00 51.53  ? 290 CYS A C   1 
ATOM   2273  O O   . CYS A 1 290 ? 115.981 131.747 100.839 1.00 51.53  ? 290 CYS A O   1 
ATOM   2274  C CB  . CYS A 1 290 ? 117.030 133.566 103.374 1.00 51.53  ? 290 CYS A CB  1 
ATOM   2275  S SG  . CYS A 1 290 ? 117.679 135.213 103.714 1.00 51.53  ? 290 CYS A SG  1 
ATOM   2276  N N   . LEU A 1 291 ? 114.776 131.357 102.705 1.00 55.63  ? 291 LEU A N   1 
ATOM   2277  C CA  . LEU A 1 291 ? 114.337 130.049 102.230 1.00 55.63  ? 291 LEU A CA  1 
ATOM   2278  C C   . LEU A 1 291 ? 113.467 130.189 100.988 1.00 55.63  ? 291 LEU A C   1 
ATOM   2279  O O   . LEU A 1 291 ? 113.588 129.402 100.042 1.00 55.63  ? 291 LEU A O   1 
ATOM   2280  C CB  . LEU A 1 291 ? 113.581 129.319 103.340 1.00 55.63  ? 291 LEU A CB  1 
ATOM   2281  C CG  . LEU A 1 291 ? 113.239 127.840 103.142 1.00 55.63  ? 291 LEU A CG  1 
ATOM   2282  C CD1 . LEU A 1 291 ? 114.309 127.126 102.337 1.00 55.63  ? 291 LEU A CD1 1 
ATOM   2283  C CD2 . LEU A 1 291 ? 113.040 127.160 104.486 1.00 55.63  ? 291 LEU A CD2 1 
ATOM   2284  N N   . LEU A 1 292 ? 112.584 131.189 100.975 1.00 53.49  ? 292 LEU A N   1 
ATOM   2285  C CA  . LEU A 1 292 ? 111.779 131.458 99.790  1.00 53.49  ? 292 LEU A CA  1 
ATOM   2286  C C   . LEU A 1 292 ? 112.659 131.806 98.600  1.00 53.49  ? 292 LEU A C   1 
ATOM   2287  O O   . LEU A 1 292 ? 112.362 131.421 97.466  1.00 53.49  ? 292 LEU A O   1 
ATOM   2288  C CB  . LEU A 1 292 ? 110.790 132.588 100.079 1.00 53.49  ? 292 LEU A CB  1 
ATOM   2289  C CG  . LEU A 1 292 ? 109.974 133.149 98.913  1.00 53.49  ? 292 LEU A CG  1 
ATOM   2290  C CD1 . LEU A 1 292 ? 108.534 133.370 99.342  1.00 53.49  ? 292 LEU A CD1 1 
ATOM   2291  C CD2 . LEU A 1 292 ? 110.579 134.446 98.399  1.00 53.49  ? 292 LEU A CD2 1 
ATOM   2292  N N   . PHE A 1 293 ? 113.742 132.546 98.838  1.00 57.08  ? 293 PHE A N   1 
ATOM   2293  C CA  . PHE A 1 293 ? 114.654 132.901 97.755  1.00 57.08  ? 293 PHE A CA  1 
ATOM   2294  C C   . PHE A 1 293 ? 115.309 131.661 97.158  1.00 57.08  ? 293 PHE A C   1 
ATOM   2295  O O   . PHE A 1 293 ? 115.379 131.509 95.932  1.00 57.08  ? 293 PHE A O   1 
ATOM   2296  C CB  . PHE A 1 293 ? 115.714 133.877 98.260  1.00 57.08  ? 293 PHE A CB  1 
ATOM   2297  C CG  . PHE A 1 293 ? 115.540 135.275 97.752  1.00 57.08  ? 293 PHE A CG  1 
ATOM   2298  C CD1 . PHE A 1 293 ? 114.595 136.115 98.312  1.00 57.08  ? 293 PHE A CD1 1 
ATOM   2299  C CD2 . PHE A 1 293 ? 116.322 135.750 96.717  1.00 57.08  ? 293 PHE A CD2 1 
ATOM   2300  C CE1 . PHE A 1 293 ? 114.433 137.404 97.847  1.00 57.08  ? 293 PHE A CE1 1 
ATOM   2301  C CE2 . PHE A 1 293 ? 116.165 137.038 96.248  1.00 57.08  ? 293 PHE A CE2 1 
ATOM   2302  C CZ  . PHE A 1 293 ? 115.219 137.866 96.814  1.00 57.08  ? 293 PHE A CZ  1 
ATOM   2303  N N   . VAL A 1 294 ? 115.798 130.759 98.012  1.00 59.18  ? 294 VAL A N   1 
ATOM   2304  C CA  . VAL A 1 294 ? 116.439 129.554 97.485  1.00 59.18  ? 294 VAL A CA  1 
ATOM   2305  C C   . VAL A 1 294 ? 115.413 128.667 96.780  1.00 59.18  ? 294 VAL A C   1 
ATOM   2306  O O   . VAL A 1 294 ? 115.708 128.045 95.748  1.00 59.18  ? 294 VAL A O   1 
ATOM   2307  C CB  . VAL A 1 294 ? 117.203 128.806 98.597  1.00 59.18  ? 294 VAL A CB  1 
ATOM   2308  C CG1 . VAL A 1 294 ? 116.303 127.856 99.366  1.00 59.18  ? 294 VAL A CG1 1 
ATOM   2309  C CG2 . VAL A 1 294 ? 118.380 128.050 98.009  1.00 59.18  ? 294 VAL A CG2 1 
ATOM   2310  N N   . PHE A 1 295 ? 114.183 128.622 97.302  1.00 68.87  ? 295 PHE A N   1 
ATOM   2311  C CA  . PHE A 1 295 ? 113.123 127.857 96.655  1.00 68.87  ? 295 PHE A CA  1 
ATOM   2312  C C   . PHE A 1 295 ? 112.786 128.437 95.288  1.00 68.87  ? 295 PHE A C   1 
ATOM   2313  O O   . PHE A 1 295 ? 112.568 127.693 94.325  1.00 68.87  ? 295 PHE A O   1 
ATOM   2314  C CB  . PHE A 1 295 ? 111.892 127.823 97.561  1.00 68.87  ? 295 PHE A CB  1 
ATOM   2315  C CG  . PHE A 1 295 ? 110.586 127.763 96.824  1.00 68.87  ? 295 PHE A CG  1 
ATOM   2316  C CD1 . PHE A 1 295 ? 110.172 126.595 96.211  1.00 68.87  ? 295 PHE A CD1 1 
ATOM   2317  C CD2 . PHE A 1 295 ? 109.762 128.875 96.760  1.00 68.87  ? 295 PHE A CD2 1 
ATOM   2318  C CE1 . PHE A 1 295 ? 108.966 126.538 95.538  1.00 68.87  ? 295 PHE A CE1 1 
ATOM   2319  C CE2 . PHE A 1 295 ? 108.556 128.825 96.089  1.00 68.87  ? 295 PHE A CE2 1 
ATOM   2320  C CZ  . PHE A 1 295 ? 108.157 127.655 95.477  1.00 68.87  ? 295 PHE A CZ  1 
ATOM   2321  N N   . SER A 1 296 ? 112.744 129.766 95.184  1.00 70.16  ? 296 SER A N   1 
ATOM   2322  C CA  . SER A 1 296 ? 112.492 130.409 93.902  1.00 70.16  ? 296 SER A CA  1 
ATOM   2323  C C   . SER A 1 296 ? 113.622 130.140 92.920  1.00 70.16  ? 296 SER A C   1 
ATOM   2324  O O   . SER A 1 296 ? 113.379 129.961 91.724  1.00 70.16  ? 296 SER A O   1 
ATOM   2325  C CB  . SER A 1 296 ? 112.302 131.912 94.096  1.00 70.16  ? 296 SER A CB  1 
ATOM   2326  O OG  . SER A 1 296 ? 113.523 132.529 94.461  1.00 70.16  ? 296 SER A OG  1 
ATOM   2327  N N   . ALA A 1 297 ? 114.866 130.125 93.403  1.00 71.39  ? 297 ALA A N   1 
ATOM   2328  C CA  . ALA A 1 297 ? 115.985 129.798 92.524  1.00 71.39  ? 297 ALA A CA  1 
ATOM   2329  C C   . ALA A 1 297 ? 115.856 128.382 91.974  1.00 71.39  ? 297 ALA A C   1 
ATOM   2330  O O   . ALA A 1 297 ? 116.048 128.151 90.771  1.00 71.39  ? 297 ALA A O   1 
ATOM   2331  C CB  . ALA A 1 297 ? 117.307 129.968 93.269  1.00 71.39  ? 297 ALA A CB  1 
ATOM   2332  N N   . LEU A 1 298 ? 115.517 127.422 92.839  1.00 75.41  ? 298 LEU A N   1 
ATOM   2333  C CA  . LEU A 1 298 ? 115.320 126.053 92.368  1.00 75.41  ? 298 LEU A CA  1 
ATOM   2334  C C   . LEU A 1 298 ? 114.162 125.971 91.379  1.00 75.41  ? 298 LEU A C   1 
ATOM   2335  O O   . LEU A 1 298 ? 114.246 125.263 90.368  1.00 75.41  ? 298 LEU A O   1 
ATOM   2336  C CB  . LEU A 1 298 ? 115.082 125.114 93.548  1.00 75.41  ? 298 LEU A CB  1 
ATOM   2337  C CG  . LEU A 1 298 ? 114.773 123.660 93.183  1.00 75.41  ? 298 LEU A CG  1 
ATOM   2338  C CD1 . LEU A 1 298 ? 115.876 123.079 92.315  1.00 75.41  ? 298 LEU A CD1 1 
ATOM   2339  C CD2 . LEU A 1 298 ? 114.575 122.818 94.432  1.00 75.41  ? 298 LEU A CD2 1 
ATOM   2340  N N   . LEU A 1 299 ? 113.070 126.688 91.656  1.00 75.60  ? 299 LEU A N   1 
ATOM   2341  C CA  . LEU A 1 299 ? 111.923 126.678 90.754  1.00 75.60  ? 299 LEU A CA  1 
ATOM   2342  C C   . LEU A 1 299 ? 112.283 127.263 89.394  1.00 75.60  ? 299 LEU A C   1 
ATOM   2343  O O   . LEU A 1 299 ? 111.854 126.748 88.355  1.00 75.60  ? 299 LEU A O   1 
ATOM   2344  C CB  . LEU A 1 299 ? 110.759 127.440 91.390  1.00 75.60  ? 299 LEU A CB  1 
ATOM   2345  C CG  . LEU A 1 299 ? 109.594 127.907 90.514  1.00 75.60  ? 299 LEU A CG  1 
ATOM   2346  C CD1 . LEU A 1 299 ? 108.287 127.762 91.271  1.00 75.60  ? 299 LEU A CD1 1 
ATOM   2347  C CD2 . LEU A 1 299 ? 109.782 129.353 90.078  1.00 75.60  ? 299 LEU A CD2 1 
ATOM   2348  N N   . GLU A 1 300 ? 113.063 128.345 89.379  1.00 76.92  ? 300 GLU A N   1 
ATOM   2349  C CA  . GLU A 1 300 ? 113.476 128.943 88.113  1.00 76.92  ? 300 GLU A CA  1 
ATOM   2350  C C   . GLU A 1 300 ? 114.392 128.008 87.334  1.00 76.92  ? 300 GLU A C   1 
ATOM   2351  O O   . GLU A 1 300 ? 114.288 127.914 86.105  1.00 76.92  ? 300 GLU A O   1 
ATOM   2352  C CB  . GLU A 1 300 ? 114.158 130.288 88.361  1.00 76.92  ? 300 GLU A CB  1 
ATOM   2353  C CG  . GLU A 1 300 ? 113.224 131.377 88.873  1.00 76.92  ? 300 GLU A CG  1 
ATOM   2354  C CD  . GLU A 1 300 ? 112.111 131.705 87.898  1.00 76.92  ? 300 GLU A CD  1 
ATOM   2355  O OE1 . GLU A 1 300 ? 112.399 131.858 86.693  1.00 76.92  ? 300 GLU A OE1 1 
ATOM   2356  O OE2 . GLU A 1 300 ? 110.947 131.814 88.337  1.00 76.92  ? 300 GLU A OE2 1 
ATOM   2357  N N   . TYR A 1 301 ? 115.297 127.308 88.023  1.00 81.47  ? 301 TYR A N   1 
ATOM   2358  C CA  . TYR A 1 301 ? 116.122 126.327 87.323  1.00 81.47  ? 301 TYR A CA  1 
ATOM   2359  C C   . TYR A 1 301 ? 115.268 125.206 86.743  1.00 81.47  ? 301 TYR A C   1 
ATOM   2360  O O   . TYR A 1 301 ? 115.519 124.735 85.627  1.00 81.47  ? 301 TYR A O   1 
ATOM   2361  C CB  . TYR A 1 301 ? 117.187 125.744 88.248  1.00 81.47  ? 301 TYR A CB  1 
ATOM   2362  C CG  . TYR A 1 301 ? 117.719 124.422 87.741  1.00 81.47  ? 301 TYR A CG  1 
ATOM   2363  C CD1 . TYR A 1 301 ? 118.480 124.360 86.582  1.00 81.47  ? 301 TYR A CD1 1 
ATOM   2364  C CD2 . TYR A 1 301 ? 117.442 123.236 88.405  1.00 81.47  ? 301 TYR A CD2 1 
ATOM   2365  C CE1 . TYR A 1 301 ? 118.962 123.158 86.106  1.00 81.47  ? 301 TYR A CE1 1 
ATOM   2366  C CE2 . TYR A 1 301 ? 117.920 122.029 87.936  1.00 81.47  ? 301 TYR A CE2 1 
ATOM   2367  C CZ  . TYR A 1 301 ? 118.679 121.996 86.787  1.00 81.47  ? 301 TYR A CZ  1 
ATOM   2368  O OH  . TYR A 1 301 ? 119.157 120.794 86.319  1.00 81.47  ? 301 TYR A OH  1 
ATOM   2369  N N   . ALA A 1 302 ? 114.266 124.750 87.497  1.00 78.59  ? 302 ALA A N   1 
ATOM   2370  C CA  . ALA A 1 302 ? 113.372 123.718 86.984  1.00 78.59  ? 302 ALA A CA  1 
ATOM   2371  C C   . ALA A 1 302 ? 112.610 124.212 85.762  1.00 78.59  ? 302 ALA A C   1 
ATOM   2372  O O   . ALA A 1 302 ? 112.408 123.463 84.801  1.00 78.59  ? 302 ALA A O   1 
ATOM   2373  C CB  . ALA A 1 302 ? 112.404 123.268 88.077  1.00 78.59  ? 302 ALA A CB  1 
ATOM   2374  N N   . ALA A 1 303 ? 112.178 125.475 85.782  1.00 77.22  ? 303 ALA A N   1 
ATOM   2375  C CA  . ALA A 1 303 ? 111.510 126.049 84.618  1.00 77.22  ? 303 ALA A CA  1 
ATOM   2376  C C   . ALA A 1 303 ? 112.446 126.104 83.417  1.00 77.22  ? 303 ALA A C   1 
ATOM   2377  O O   . ALA A 1 303 ? 112.032 125.830 82.283  1.00 77.22  ? 303 ALA A O   1 
ATOM   2378  C CB  . ALA A 1 303 ? 110.983 127.444 84.951  1.00 77.22  ? 303 ALA A CB  1 
ATOM   2379  N N   . VAL A 1 304 ? 113.711 126.463 83.646  1.00 77.75  ? 304 VAL A N   1 
ATOM   2380  C CA  . VAL A 1 304 ? 114.688 126.492 82.559  1.00 77.75  ? 304 VAL A CA  1 
ATOM   2381  C C   . VAL A 1 304 ? 114.872 125.099 81.974  1.00 77.75  ? 304 VAL A C   1 
ATOM   2382  O O   . VAL A 1 304 ? 114.924 124.923 80.750  1.00 77.75  ? 304 VAL A O   1 
ATOM   2383  C CB  . VAL A 1 304 ? 116.022 127.080 83.055  1.00 77.75  ? 304 VAL A CB  1 
ATOM   2384  C CG1 . VAL A 1 304 ? 117.145 126.754 82.082  1.00 77.75  ? 304 VAL A CG1 1 
ATOM   2385  C CG2 . VAL A 1 304 ? 115.899 128.581 83.250  1.00 77.75  ? 304 VAL A CG2 1 
ATOM   2386  N N   . ASN A 1 305 ? 114.971 124.087 82.838  1.00 76.23  ? 305 ASN A N   1 
ATOM   2387  C CA  . ASN A 1 305 ? 115.092 122.713 82.360  1.00 76.23  ? 305 ASN A CA  1 
ATOM   2388  C C   . ASN A 1 305 ? 113.856 122.295 81.574  1.00 76.23  ? 305 ASN A C   1 
ATOM   2389  O O   . ASN A 1 305 ? 113.961 121.598 80.558  1.00 76.23  ? 305 ASN A O   1 
ATOM   2390  C CB  . ASN A 1 305 ? 115.328 121.767 83.538  1.00 76.23  ? 305 ASN A CB  1 
ATOM   2391  C CG  . ASN A 1 305 ? 115.917 120.436 83.112  1.00 76.23  ? 305 ASN A CG  1 
ATOM   2392  O OD1 . ASN A 1 305 ? 115.521 119.861 82.100  1.00 76.23  ? 305 ASN A OD1 1 
ATOM   2393  N ND2 . ASN A 1 305 ? 116.871 119.939 83.889  1.00 76.23  ? 305 ASN A ND2 1 
ATOM   2394  N N   . PHE A 1 306 ? 112.674 122.708 82.035  1.00 77.03  ? 306 PHE A N   1 
ATOM   2395  C CA  . PHE A 1 306 ? 111.442 122.398 81.318  1.00 77.03  ? 306 PHE A CA  1 
ATOM   2396  C C   . PHE A 1 306 ? 111.437 123.026 79.931  1.00 77.03  ? 306 PHE A C   1 
ATOM   2397  O O   . PHE A 1 306 ? 111.033 122.387 78.953  1.00 77.03  ? 306 PHE A O   1 
ATOM   2398  C CB  . PHE A 1 306 ? 110.238 122.869 82.136  1.00 77.03  ? 306 PHE A CB  1 
ATOM   2399  C CG  . PHE A 1 306 ? 109.027 123.202 81.311  1.00 77.03  ? 306 PHE A CG  1 
ATOM   2400  C CD1 . PHE A 1 306 ? 108.203 122.200 80.828  1.00 77.03  ? 306 PHE A CD1 1 
ATOM   2401  C CD2 . PHE A 1 306 ? 108.700 124.520 81.039  1.00 77.03  ? 306 PHE A CD2 1 
ATOM   2402  C CE1 . PHE A 1 306 ? 107.085 122.505 80.075  1.00 77.03  ? 306 PHE A CE1 1 
ATOM   2403  C CE2 . PHE A 1 306 ? 107.583 124.831 80.288  1.00 77.03  ? 306 PHE A CE2 1 
ATOM   2404  C CZ  . PHE A 1 306 ? 106.775 123.822 79.806  1.00 77.03  ? 306 PHE A CZ  1 
ATOM   2405  N N   . VAL A 1 307 ? 111.883 124.279 79.826  1.00 74.30  ? 307 VAL A N   1 
ATOM   2406  C CA  . VAL A 1 307 ? 111.948 124.933 78.523  1.00 74.30  ? 307 VAL A CA  1 
ATOM   2407  C C   . VAL A 1 307 ? 113.051 124.318 77.668  1.00 74.30  ? 307 VAL A C   1 
ATOM   2408  O O   . VAL A 1 307 ? 112.872 124.100 76.464  1.00 74.30  ? 307 VAL A O   1 
ATOM   2409  C CB  . VAL A 1 307 ? 112.140 126.450 78.698  1.00 74.30  ? 307 VAL A CB  1 
ATOM   2410  C CG1 . VAL A 1 307 ? 112.441 127.110 77.363  1.00 74.30  ? 307 VAL A CG1 1 
ATOM   2411  C CG2 . VAL A 1 307 ? 110.904 127.067 79.331  1.00 74.30  ? 307 VAL A CG2 1 
ATOM   2412  N N   . SER A 1 308 ? 114.202 124.020 78.276  1.00 76.15  ? 308 SER A N   1 
ATOM   2413  C CA  . SER A 1 308 ? 115.322 123.467 77.518  1.00 76.15  ? 308 SER A CA  1 
ATOM   2414  C C   . SER A 1 308 ? 114.986 122.098 76.942  1.00 76.15  ? 308 SER A C   1 
ATOM   2415  O O   . SER A 1 308 ? 115.367 121.784 75.808  1.00 76.15  ? 308 SER A O   1 
ATOM   2416  C CB  . SER A 1 308 ? 116.566 123.382 78.401  1.00 76.15  ? 308 SER A CB  1 
ATOM   2417  O OG  . SER A 1 308 ? 117.629 122.740 77.718  1.00 76.15  ? 308 SER A OG  1 
ATOM   2418  N N   . ARG A 1 309 ? 114.279 121.266 77.705  1.00 75.79  ? 309 ARG A N   1 
ATOM   2419  C CA  . ARG A 1 309 ? 113.907 119.943 77.224  1.00 75.79  ? 309 ARG A CA  1 
ATOM   2420  C C   . ARG A 1 309 ? 112.821 120.059 76.163  1.00 75.79  ? 309 ARG A C   1 
ATOM   2421  O O   . ARG A 1 309 ? 111.631 120.118 76.489  1.00 75.79  ? 309 ARG A O   1 
ATOM   2422  C CB  . ARG A 1 309 ? 113.435 119.058 78.379  1.00 75.79  ? 309 ARG A CB  1 
ATOM   2423  N N   . GLN A 1 310 ? 113.232 120.096 74.898  1.00 76.69  ? 310 GLN A N   1 
ATOM   2424  C CA  . GLN A 1 310 ? 112.329 120.246 73.758  1.00 76.69  ? 310 GLN A CA  1 
ATOM   2425  C C   . GLN A 1 310 ? 111.496 121.523 73.868  1.00 76.69  ? 310 GLN A C   1 
ATOM   2426  O O   . GLN A 1 310 ? 110.427 121.536 74.480  1.00 76.69  ? 310 GLN A O   1 
ATOM   2427  C CB  . GLN A 1 310 ? 111.416 119.021 73.624  1.00 76.69  ? 310 GLN A CB  1 
ATOM   2428  C CG  . GLN A 1 310 ? 110.455 119.065 72.441  1.00 76.69  ? 310 GLN A CG  1 
ATOM   2429  C CD  . GLN A 1 310 ? 111.134 118.823 71.102  1.00 76.69  ? 310 GLN A CD  1 
ATOM   2430  O OE1 . GLN A 1 310 ? 112.356 118.913 70.980  1.00 76.69  ? 310 GLN A OE1 1 
ATOM   2431  N NE2 . GLN A 1 310 ? 110.337 118.514 70.087  1.00 76.69  ? 310 GLN A NE2 1 
ATOM   2432  N N   . LYS A 1 377 ? 113.753 125.735 66.418  1.00 97.15  ? 386 LYS A N   1 
ATOM   2433  C CA  . LYS A 1 377 ? 112.681 126.051 67.355  1.00 97.15  ? 386 LYS A CA  1 
ATOM   2434  C C   . LYS A 1 377 ? 113.016 127.304 68.157  1.00 97.15  ? 386 LYS A C   1 
ATOM   2435  O O   . LYS A 1 377 ? 112.122 127.993 68.648  1.00 97.15  ? 386 LYS A O   1 
ATOM   2436  C CB  . LYS A 1 377 ? 112.426 124.873 68.295  1.00 97.15  ? 386 LYS A CB  1 
ATOM   2437  C CG  . LYS A 1 377 ? 111.048 124.873 68.932  1.00 97.15  ? 386 LYS A CG  1 
ATOM   2438  C CD  . LYS A 1 377 ? 110.904 123.742 69.937  1.00 97.15  ? 386 LYS A CD  1 
ATOM   2439  C CE  . LYS A 1 377 ? 109.519 123.736 70.564  1.00 97.15  ? 386 LYS A CE  1 
ATOM   2440  N NZ  . LYS A 1 377 ? 109.398 122.713 71.639  1.00 97.15  ? 386 LYS A NZ  1 
ATOM   2441  N N   . VAL A 1 378 ? 114.315 127.585 68.269  1.00 99.53  ? 387 VAL A N   1 
ATOM   2442  C CA  . VAL A 1 378 ? 114.835 128.735 69.006  1.00 99.53  ? 387 VAL A CA  1 
ATOM   2443  C C   . VAL A 1 378 ? 114.302 128.599 70.434  1.00 99.53  ? 387 VAL A C   1 
ATOM   2444  O O   . VAL A 1 378 ? 113.648 129.493 70.979  1.00 99.53  ? 387 VAL A O   1 
ATOM   2445  C CB  . VAL A 1 378 ? 114.463 130.061 68.299  1.00 99.53  ? 387 VAL A CB  1 
ATOM   2446  C CG1 . VAL A 1 378 ? 114.721 131.310 69.158  1.00 99.53  ? 387 VAL A CG1 1 
ATOM   2447  C CG2 . VAL A 1 378 ? 115.194 130.172 66.968  1.00 99.53  ? 387 VAL A CG2 1 
ATOM   2448  N N   . PHE A 1 379 ? 114.512 127.419 71.020  1.00 96.83  ? 388 PHE A N   1 
ATOM   2449  C CA  . PHE A 1 379 ? 114.158 127.184 72.414  1.00 96.83  ? 388 PHE A CA  1 
ATOM   2450  C C   . PHE A 1 379 ? 115.358 127.343 73.336  1.00 96.83  ? 388 PHE A C   1 
ATOM   2451  O O   . PHE A 1 379 ? 115.216 127.832 74.462  1.00 96.83  ? 388 PHE A O   1 
ATOM   2452  C CB  . PHE A 1 379 ? 113.554 125.787 72.578  1.00 96.83  ? 388 PHE A CB  1 
ATOM   2453  N N   . ILE A 1 380 ? 116.544 126.939 72.873  1.00 94.00  ? 389 ILE A N   1 
ATOM   2454  C CA  . ILE A 1 380 ? 117.757 127.136 73.661  1.00 94.00  ? 389 ILE A CA  1 
ATOM   2455  C C   . ILE A 1 380 ? 118.039 128.623 73.828  1.00 94.00  ? 389 ILE A C   1 
ATOM   2456  O O   . ILE A 1 380 ? 118.520 129.066 74.879  1.00 94.00  ? 389 ILE A O   1 
ATOM   2457  C CB  . ILE A 1 380 ? 118.943 126.402 73.009  1.00 94.00  ? 389 ILE A CB  1 
ATOM   2458  C CG1 . ILE A 1 380 ? 118.541 124.977 72.624  1.00 94.00  ? 389 ILE A CG1 1 
ATOM   2459  C CG2 . ILE A 1 380 ? 120.141 126.386 73.946  1.00 94.00  ? 389 ILE A CG2 1 
ATOM   2460  C CD1 . ILE A 1 380 ? 118.093 124.129 73.794  1.00 94.00  ? 389 ILE A CD1 1 
ATOM   2461  N N   . ASP A 1 381 ? 117.744 129.415 72.796  1.00 96.62  ? 390 ASP A N   1 
ATOM   2462  C CA  . ASP A 1 381 ? 117.885 130.862 72.914  1.00 96.62  ? 390 ASP A CA  1 
ATOM   2463  C C   . ASP A 1 381 ? 116.953 131.416 73.983  1.00 96.62  ? 390 ASP A C   1 
ATOM   2464  O O   . ASP A 1 381 ? 117.352 132.274 74.778  1.00 96.62  ? 390 ASP A O   1 
ATOM   2465  C CB  . ASP A 1 381 ? 117.615 131.529 71.566  1.00 96.62  ? 390 ASP A CB  1 
ATOM   2466  C CG  . ASP A 1 381 ? 117.994 132.998 71.556  1.00 96.62  ? 390 ASP A CG  1 
ATOM   2467  O OD1 . ASP A 1 381 ? 118.649 133.454 72.516  1.00 96.62  ? 390 ASP A OD1 1 
ATOM   2468  O OD2 . ASP A 1 381 ? 117.637 133.697 70.585  1.00 96.62  ? 390 ASP A OD2 1 
ATOM   2469  N N   . ARG A 1 382 ? 115.708 130.935 74.021  1.00 93.71  ? 391 ARG A N   1 
ATOM   2470  C CA  . ARG A 1 382 ? 114.776 131.376 75.055  1.00 93.71  ? 391 ARG A CA  1 
ATOM   2471  C C   . ARG A 1 382 ? 115.259 130.970 76.442  1.00 93.71  ? 391 ARG A C   1 
ATOM   2472  O O   . ARG A 1 382 ? 115.146 131.745 77.400  1.00 93.71  ? 391 ARG A O   1 
ATOM   2473  C CB  . ARG A 1 382 ? 113.381 130.813 74.784  1.00 93.71  ? 391 ARG A CB  1 
ATOM   2474  C CG  . ARG A 1 382 ? 112.248 131.741 75.197  1.00 93.71  ? 391 ARG A CG  1 
ATOM   2475  C CD  . ARG A 1 382 ? 110.941 131.374 74.509  1.00 93.71  ? 391 ARG A CD  1 
ATOM   2476  N NE  . ARG A 1 382 ? 110.973 131.660 73.079  1.00 93.71  ? 391 ARG A NE  1 
ATOM   2477  C CZ  . ARG A 1 382 ? 110.614 130.802 72.134  1.00 93.71  ? 391 ARG A CZ  1 
ATOM   2478  N NH1 . ARG A 1 382 ? 110.191 129.584 72.431  1.00 93.71  ? 391 ARG A NH1 1 
ATOM   2479  N NH2 . ARG A 1 382 ? 110.682 131.175 70.859  1.00 93.71  ? 391 ARG A NH2 1 
ATOM   2480  N N   . ALA A 1 383 ? 115.795 129.754 76.570  1.00 83.50  ? 392 ALA A N   1 
ATOM   2481  C CA  . ALA A 1 383 ? 116.312 129.305 77.858  1.00 83.50  ? 392 ALA A CA  1 
ATOM   2482  C C   . ALA A 1 383 ? 117.471 130.180 78.319  1.00 83.50  ? 392 ALA A C   1 
ATOM   2483  O O   . ALA A 1 383 ? 117.527 130.598 79.481  1.00 83.50  ? 392 ALA A O   1 
ATOM   2484  C CB  . ALA A 1 383 ? 116.743 127.841 77.767  1.00 83.50  ? 392 ALA A CB  1 
ATOM   2485  N N   . LYS A 1 384 ? 118.403 130.482 77.413  1.00 82.83  ? 393 LYS A N   1 
ATOM   2486  C CA  . LYS A 1 384 ? 119.528 131.340 77.771  1.00 82.83  ? 393 LYS A CA  1 
ATOM   2487  C C   . LYS A 1 384 ? 119.057 132.746 78.124  1.00 82.83  ? 393 LYS A C   1 
ATOM   2488  O O   . LYS A 1 384 ? 119.577 133.369 79.058  1.00 82.83  ? 393 LYS A O   1 
ATOM   2489  C CB  . LYS A 1 384 ? 120.541 131.383 76.628  1.00 82.83  ? 393 LYS A CB  1 
ATOM   2490  N N   . LYS A 1 385 ? 118.074 133.264 77.382  1.00 84.64  ? 394 LYS A N   1 
ATOM   2491  C CA  . LYS A 1 385 ? 117.557 134.599 77.658  1.00 84.64  ? 394 LYS A CA  1 
ATOM   2492  C C   . LYS A 1 385 ? 116.917 134.665 79.037  1.00 84.64  ? 394 LYS A C   1 
ATOM   2493  O O   . LYS A 1 385 ? 117.158 135.607 79.797  1.00 84.64  ? 394 LYS A O   1 
ATOM   2494  C CB  . LYS A 1 385 ? 116.555 135.005 76.577  1.00 84.64  ? 394 LYS A CB  1 
ATOM   2495  C CG  . LYS A 1 385 ? 115.707 136.215 76.938  1.00 84.64  ? 394 LYS A CG  1 
ATOM   2496  C CD  . LYS A 1 385 ? 116.561 137.460 77.118  1.00 84.64  ? 394 LYS A CD  1 
ATOM   2497  C CE  . LYS A 1 385 ? 115.708 138.668 77.468  1.00 84.64  ? 394 LYS A CE  1 
ATOM   2498  N NZ  . LYS A 1 385 ? 114.688 138.953 76.422  1.00 84.64  ? 394 LYS A NZ  1 
ATOM   2499  N N   . ILE A 1 386 ? 116.099 133.667 79.382  1.00 79.51  ? 395 ILE A N   1 
ATOM   2500  C CA  . ILE A 1 386 ? 115.463 133.682 80.696  1.00 79.51  ? 395 ILE A CA  1 
ATOM   2501  C C   . ILE A 1 386 ? 116.501 133.477 81.794  1.00 79.51  ? 395 ILE A C   1 
ATOM   2502  O O   . ILE A 1 386 ? 116.394 134.072 82.876  1.00 79.51  ? 395 ILE A O   1 
ATOM   2503  C CB  . ILE A 1 386 ? 114.319 132.648 80.766  1.00 79.51  ? 395 ILE A CB  1 
ATOM   2504  C CG1 . ILE A 1 386 ? 113.349 133.005 81.893  1.00 79.51  ? 395 ILE A CG1 1 
ATOM   2505  C CG2 . ILE A 1 386 ? 114.841 131.235 80.956  1.00 79.51  ? 395 ILE A CG2 1 
ATOM   2506  C CD1 . ILE A 1 386 ? 112.625 134.315 81.681  1.00 79.51  ? 395 ILE A CD1 1 
ATOM   2507  N N   . ASP A 1 387 ? 117.531 132.665 81.535  1.00 76.75  ? 396 ASP A N   1 
ATOM   2508  C CA  . ASP A 1 387 ? 118.597 132.483 82.513  1.00 76.75  ? 396 ASP A CA  1 
ATOM   2509  C C   . ASP A 1 387 ? 119.306 133.801 82.796  1.00 76.75  ? 396 ASP A C   1 
ATOM   2510  O O   . ASP A 1 387 ? 119.501 134.177 83.956  1.00 76.75  ? 396 ASP A O   1 
ATOM   2511  C CB  . ASP A 1 387 ? 119.588 131.433 82.010  1.00 76.75  ? 396 ASP A CB  1 
ATOM   2512  C CG  . ASP A 1 387 ? 120.693 131.148 83.007  1.00 76.75  ? 396 ASP A CG  1 
ATOM   2513  O OD1 . ASP A 1 387 ? 120.467 130.334 83.927  1.00 76.75  ? 396 ASP A OD1 1 
ATOM   2514  O OD2 . ASP A 1 387 ? 121.786 131.738 82.871  1.00 76.75  ? 396 ASP A OD2 1 
ATOM   2515  N N   . THR A 1 388 ? 119.685 134.526 81.741  1.00 76.05  ? 397 THR A N   1 
ATOM   2516  C CA  . THR A 1 388 ? 120.351 135.812 81.929  1.00 76.05  ? 397 THR A CA  1 
ATOM   2517  C C   . THR A 1 388 ? 119.423 136.823 82.591  1.00 76.05  ? 397 THR A C   1 
ATOM   2518  O O   . THR A 1 388 ? 119.854 137.609 83.446  1.00 76.05  ? 397 THR A O   1 
ATOM   2519  C CB  . THR A 1 388 ? 120.853 136.347 80.588  1.00 76.05  ? 397 THR A CB  1 
ATOM   2520  N N   . ILE A 1 389 ? 118.143 136.815 82.211  1.00 77.84  ? 398 ILE A N   1 
ATOM   2521  C CA  . ILE A 1 389 ? 117.187 137.763 82.774  1.00 77.84  ? 398 ILE A CA  1 
ATOM   2522  C C   . ILE A 1 389 ? 117.059 137.558 84.276  1.00 77.84  ? 398 ILE A C   1 
ATOM   2523  O O   . ILE A 1 389 ? 117.082 138.517 85.054  1.00 77.84  ? 398 ILE A O   1 
ATOM   2524  C CB  . ILE A 1 389 ? 115.825 137.635 82.069  1.00 77.84  ? 398 ILE A CB  1 
ATOM   2525  N N   . SER A 1 390 ? 116.937 136.303 84.711  1.00 80.10  ? 399 SER A N   1 
ATOM   2526  C CA  . SER A 1 390 ? 116.825 136.057 86.145  1.00 80.10  ? 399 SER A CA  1 
ATOM   2527  C C   . SER A 1 390 ? 118.156 136.273 86.858  1.00 80.10  ? 399 SER A C   1 
ATOM   2528  O O   . SER A 1 390 ? 118.170 136.713 88.014  1.00 80.10  ? 399 SER A O   1 
ATOM   2529  C CB  . SER A 1 390 ? 116.294 134.648 86.404  1.00 80.10  ? 399 SER A CB  1 
ATOM   2530  O OG  . SER A 1 390 ? 117.344 133.760 86.715  1.00 80.10  ? 399 SER A OG  1 
ATOM   2531  N N   . ARG A 1 391 ? 119.278 135.988 86.188  1.00 79.23  ? 400 ARG A N   1 
ATOM   2532  C CA  . ARG A 1 391 ? 120.584 136.257 86.780  1.00 79.23  ? 400 ARG A CA  1 
ATOM   2533  C C   . ARG A 1 391 ? 120.792 137.743 87.022  1.00 79.23  ? 400 ARG A C   1 
ATOM   2534  O O   . ARG A 1 391 ? 121.530 138.126 87.936  1.00 79.23  ? 400 ARG A O   1 
ATOM   2535  C CB  . ARG A 1 391 ? 121.693 135.714 85.878  1.00 79.23  ? 400 ARG A CB  1 
ATOM   2536  N N   . ALA A 1 392 ? 120.179 138.590 86.200  1.00 81.55  ? 401 ALA A N   1 
ATOM   2537  C CA  . ALA A 1 392 ? 120.225 140.027 86.435  1.00 81.55  ? 401 ALA A CA  1 
ATOM   2538  C C   . ALA A 1 392 ? 119.142 140.502 87.394  1.00 81.55  ? 401 ALA A C   1 
ATOM   2539  O O   . ALA A 1 392 ? 119.336 141.505 88.089  1.00 81.55  ? 401 ALA A O   1 
ATOM   2540  C CB  . ALA A 1 392 ? 120.104 140.786 85.111  1.00 81.55  ? 401 ALA A CB  1 
ATOM   2541  N N   . CYS A 1 393 ? 118.003 139.806 87.443  1.00 79.23  ? 402 CYS A N   1 
ATOM   2542  C CA  . CYS A 1 393 ? 116.892 140.232 88.287  1.00 79.23  ? 402 CYS A CA  1 
ATOM   2543  C C   . CYS A 1 393 ? 117.125 139.899 89.755  1.00 79.23  ? 402 CYS A C   1 
ATOM   2544  O O   . CYS A 1 393 ? 116.706 140.656 90.638  1.00 79.23  ? 402 CYS A O   1 
ATOM   2545  C CB  . CYS A 1 393 ? 115.593 139.589 87.799  1.00 79.23  ? 402 CYS A CB  1 
ATOM   2546  S SG  . CYS A 1 393 ? 114.135 140.012 88.779  1.00 79.23  ? 402 CYS A SG  1 
ATOM   2547  N N   . PHE A 1 394 ? 117.775 138.771 90.036  1.00 76.51  ? 403 PHE A N   1 
ATOM   2548  C CA  . PHE A 1 394 ? 118.005 138.378 91.424  1.00 76.51  ? 403 PHE A CA  1 
ATOM   2549  C C   . PHE A 1 394 ? 118.822 139.389 92.227  1.00 76.51  ? 403 PHE A C   1 
ATOM   2550  O O   . PHE A 1 394 ? 118.464 139.633 93.393  1.00 76.51  ? 403 PHE A O   1 
ATOM   2551  C CB  . PHE A 1 394 ? 118.660 136.991 91.467  1.00 76.51  ? 403 PHE A CB  1 
ATOM   2552  C CG  . PHE A 1 394 ? 117.678 135.857 91.574  1.00 76.51  ? 403 PHE A CG  1 
ATOM   2553  C CD1 . PHE A 1 394 ? 116.316 136.102 91.612  1.00 76.51  ? 403 PHE A CD1 1 
ATOM   2554  C CD2 . PHE A 1 394 ? 118.119 134.546 91.640  1.00 76.51  ? 403 PHE A CD2 1 
ATOM   2555  C CE1 . PHE A 1 394 ? 115.411 135.062 91.711  1.00 76.51  ? 403 PHE A CE1 1 
ATOM   2556  C CE2 . PHE A 1 394 ? 117.219 133.502 91.739  1.00 76.51  ? 403 PHE A CE2 1 
ATOM   2557  C CZ  . PHE A 1 394 ? 115.864 133.760 91.775  1.00 76.51  ? 403 PHE A CZ  1 
ATOM   2558  N N   . PRO A 1 395 ? 119.919 139.970 91.715  1.00 76.66  ? 404 PRO A N   1 
ATOM   2559  C CA  . PRO A 1 395 ? 120.666 140.937 92.539  1.00 76.66  ? 404 PRO A CA  1 
ATOM   2560  C C   . PRO A 1 395 ? 119.832 142.111 93.006  1.00 76.66  ? 404 PRO A C   1 
ATOM   2561  O O   . PRO A 1 395 ? 119.919 142.492 94.179  1.00 76.66  ? 404 PRO A O   1 
ATOM   2562  C CB  . PRO A 1 395 ? 121.800 141.385 91.608  1.00 76.66  ? 404 PRO A CB  1 
ATOM   2563  C CG  . PRO A 1 395 ? 121.999 140.244 90.696  1.00 76.66  ? 404 PRO A CG  1 
ATOM   2564  C CD  . PRO A 1 395 ? 120.631 139.678 90.458  1.00 76.66  ? 404 PRO A CD  1 
ATOM   2565  N N   . LEU A 1 396 ? 119.014 142.688 92.125  1.00 76.96  ? 405 LEU A N   1 
ATOM   2566  C CA  . LEU A 1 396 ? 118.196 143.825 92.529  1.00 76.96  ? 405 LEU A CA  1 
ATOM   2567  C C   . LEU A 1 396 ? 117.208 143.425 93.615  1.00 76.96  ? 405 LEU A C   1 
ATOM   2568  O O   . LEU A 1 396 ? 117.040 144.145 94.606  1.00 76.96  ? 405 LEU A O   1 
ATOM   2569  C CB  . LEU A 1 396 ? 117.465 144.407 91.319  1.00 76.96  ? 405 LEU A CB  1 
ATOM   2570  C CG  . LEU A 1 396 ? 117.090 145.890 91.387  1.00 76.96  ? 405 LEU A CG  1 
ATOM   2571  C CD1 . LEU A 1 396 ? 117.065 146.496 89.994  1.00 76.96  ? 405 LEU A CD1 1 
ATOM   2572  C CD2 . LEU A 1 396 ? 115.751 146.094 92.082  1.00 76.96  ? 405 LEU A CD2 1 
ATOM   2573  N N   . ALA A 1 397 ? 116.561 142.269 93.456  1.00 74.90  ? 406 ALA A N   1 
ATOM   2574  C CA  . ALA A 1 397 ? 115.583 141.823 94.442  1.00 74.90  ? 406 ALA A CA  1 
ATOM   2575  C C   . ALA A 1 397 ? 116.239 141.578 95.795  1.00 74.90  ? 406 ALA A C   1 
ATOM   2576  O O   . ALA A 1 397 ? 115.751 142.048 96.830  1.00 74.90  ? 406 ALA A O   1 
ATOM   2577  C CB  . ALA A 1 397 ? 114.879 140.560 93.947  1.00 74.90  ? 406 ALA A CB  1 
ATOM   2578  N N   . PHE A 1 398 ? 117.353 140.842 95.806  1.00 71.01  ? 407 PHE A N   1 
ATOM   2579  C CA  . PHE A 1 398 ? 118.020 140.558 97.072  1.00 71.01  ? 407 PHE A CA  1 
ATOM   2580  C C   . PHE A 1 398 ? 118.516 141.836 97.733  1.00 71.01  ? 407 PHE A C   1 
ATOM   2581  O O   . PHE A 1 398 ? 118.353 142.015 98.945  1.00 71.01  ? 407 PHE A O   1 
ATOM   2582  C CB  . PHE A 1 398 ? 119.180 139.587 96.864  1.00 71.01  ? 407 PHE A CB  1 
ATOM   2583  C CG  . PHE A 1 398 ? 119.504 138.767 98.082  1.00 71.01  ? 407 PHE A CG  1 
ATOM   2584  C CD1 . PHE A 1 398 ? 118.803 138.946 99.262  1.00 71.01  ? 407 PHE A CD1 1 
ATOM   2585  C CD2 . PHE A 1 398 ? 120.525 137.835 98.054  1.00 71.01  ? 407 PHE A CD2 1 
ATOM   2586  C CE1 . PHE A 1 398 ? 119.102 138.200 100.384 1.00 71.01  ? 407 PHE A CE1 1 
ATOM   2587  C CE2 . PHE A 1 398 ? 120.829 137.090 99.176  1.00 71.01  ? 407 PHE A CE2 1 
ATOM   2588  C CZ  . PHE A 1 398 ? 120.116 137.271 100.340 1.00 71.01  ? 407 PHE A CZ  1 
ATOM   2589  N N   . LEU A 1 399 ? 119.120 142.738 96.957  1.00 73.26  ? 408 LEU A N   1 
ATOM   2590  C CA  . LEU A 1 399 ? 119.648 143.965 97.538  1.00 73.26  ? 408 LEU A CA  1 
ATOM   2591  C C   . LEU A 1 399 ? 118.531 144.835 98.099  1.00 73.26  ? 408 LEU A C   1 
ATOM   2592  O O   . LEU A 1 399 ? 118.658 145.377 99.204  1.00 73.26  ? 408 LEU A O   1 
ATOM   2593  C CB  . LEU A 1 399 ? 120.460 144.731 96.495  1.00 73.26  ? 408 LEU A CB  1 
ATOM   2594  C CG  . LEU A 1 399 ? 121.371 145.848 97.008  1.00 73.26  ? 408 LEU A CG  1 
ATOM   2595  C CD1 . LEU A 1 399 ? 122.668 145.875 96.215  1.00 73.26  ? 408 LEU A CD1 1 
ATOM   2596  C CD2 . LEU A 1 399 ? 120.675 147.199 96.939  1.00 73.26  ? 408 LEU A CD2 1 
ATOM   2597  N N   . ILE A 1 400 ? 117.424 144.973 97.364  1.00 74.03  ? 409 ILE A N   1 
ATOM   2598  C CA  . ILE A 1 400 ? 116.343 145.824 97.848  1.00 74.03  ? 409 ILE A CA  1 
ATOM   2599  C C   . ILE A 1 400 ? 115.698 145.216 99.087  1.00 74.03  ? 409 ILE A C   1 
ATOM   2600  O O   . ILE A 1 400 ? 115.404 145.930 100.054 1.00 74.03  ? 409 ILE A O   1 
ATOM   2601  C CB  . ILE A 1 400 ? 115.316 146.109 96.733  1.00 74.03  ? 409 ILE A CB  1 
ATOM   2602  C CG1 . ILE A 1 400 ? 114.355 147.214 97.174  1.00 74.03  ? 409 ILE A CG1 1 
ATOM   2603  C CG2 . ILE A 1 400 ? 114.528 144.870 96.350  1.00 74.03  ? 409 ILE A CG2 1 
ATOM   2604  C CD1 . ILE A 1 400 ? 115.045 148.489 97.606  1.00 74.03  ? 409 ILE A CD1 1 
ATOM   2605  N N   . PHE A 1 401 ? 115.496 143.894 99.105  1.00 68.83  ? 410 PHE A N   1 
ATOM   2606  C CA  . PHE A 1 401 ? 114.925 143.271 100.295 1.00 68.83  ? 410 PHE A CA  1 
ATOM   2607  C C   . PHE A 1 401 ? 115.849 143.429 101.493 1.00 68.83  ? 410 PHE A C   1 
ATOM   2608  O O   . PHE A 1 401 ? 115.400 143.754 102.597 1.00 68.83  ? 410 PHE A O   1 
ATOM   2609  C CB  . PHE A 1 401 ? 114.639 141.791 100.060 1.00 68.83  ? 410 PHE A CB  1 
ATOM   2610  C CG  . PHE A 1 401 ? 114.569 140.999 101.333 1.00 68.83  ? 410 PHE A CG  1 
ATOM   2611  C CD1 . PHE A 1 401 ? 113.489 141.135 102.187 1.00 68.83  ? 410 PHE A CD1 1 
ATOM   2612  C CD2 . PHE A 1 401 ? 115.600 140.149 101.695 1.00 68.83  ? 410 PHE A CD2 1 
ATOM   2613  C CE1 . PHE A 1 401 ? 113.428 140.424 103.366 1.00 68.83  ? 410 PHE A CE1 1 
ATOM   2614  C CE2 . PHE A 1 401 ? 115.543 139.435 102.874 1.00 68.83  ? 410 PHE A CE2 1 
ATOM   2615  C CZ  . PHE A 1 401 ? 114.458 139.576 103.712 1.00 68.83  ? 410 PHE A CZ  1 
ATOM   2616  N N   . ASN A 1 402 ? 117.145 143.181 101.298 1.00 71.16  ? 411 ASN A N   1 
ATOM   2617  C CA  . ASN A 1 402 ? 118.090 143.283 102.401 1.00 71.16  ? 411 ASN A CA  1 
ATOM   2618  C C   . ASN A 1 402 ? 118.126 144.699 102.954 1.00 71.16  ? 411 ASN A C   1 
ATOM   2619  O O   . ASN A 1 402 ? 118.058 144.903 104.172 1.00 71.16  ? 411 ASN A O   1 
ATOM   2620  C CB  . ASN A 1 402 ? 119.480 142.845 101.939 1.00 71.16  ? 411 ASN A CB  1 
ATOM   2621  C CG  . ASN A 1 402 ? 120.553 143.120 102.972 1.00 71.16  ? 411 ASN A CG  1 
ATOM   2622  O OD1 . ASN A 1 402 ? 120.312 143.026 104.175 1.00 71.16  ? 411 ASN A OD1 1 
ATOM   2623  N ND2 . ASN A 1 402 ? 121.747 143.464 102.506 1.00 71.16  ? 411 ASN A ND2 1 
ATOM   2624  N N   . ILE A 1 403 ? 118.206 145.696 102.070 1.00 67.67  ? 412 ILE A N   1 
ATOM   2625  C CA  . ILE A 1 403 ? 118.300 147.072 102.540 1.00 67.67  ? 412 ILE A CA  1 
ATOM   2626  C C   . ILE A 1 403 ? 117.003 147.497 103.219 1.00 67.67  ? 412 ILE A C   1 
ATOM   2627  O O   . ILE A 1 403 ? 117.031 148.178 104.249 1.00 67.67  ? 412 ILE A O   1 
ATOM   2628  C CB  . ILE A 1 403 ? 118.703 148.013 101.385 1.00 67.67  ? 412 ILE A CB  1 
ATOM   2629  C CG1 . ILE A 1 403 ? 119.458 149.225 101.932 1.00 67.67  ? 412 ILE A CG1 1 
ATOM   2630  C CG2 . ILE A 1 403 ? 117.504 148.453 100.556 1.00 67.67  ? 412 ILE A CG2 1 
ATOM   2631  C CD1 . ILE A 1 403 ? 120.776 148.875 102.589 1.00 67.67  ? 412 ILE A CD1 1 
ATOM   2632  N N   . PHE A 1 404 ? 115.852 147.061 102.695 1.00 69.26  ? 413 PHE A N   1 
ATOM   2633  C CA  . PHE A 1 404 ? 114.577 147.442 103.291 1.00 69.26  ? 413 PHE A CA  1 
ATOM   2634  C C   . PHE A 1 404 ? 114.407 146.813 104.667 1.00 69.26  ? 413 PHE A C   1 
ATOM   2635  O O   . PHE A 1 404 ? 114.034 147.492 105.632 1.00 69.26  ? 413 PHE A O   1 
ATOM   2636  C CB  . PHE A 1 404 ? 113.430 147.039 102.365 1.00 69.26  ? 413 PHE A CB  1 
ATOM   2637  C CG  . PHE A 1 404 ? 112.215 147.909 102.490 1.00 69.26  ? 413 PHE A CG  1 
ATOM   2638  C CD1 . PHE A 1 404 ? 112.333 149.288 102.488 1.00 69.26  ? 413 PHE A CD1 1 
ATOM   2639  C CD2 . PHE A 1 404 ? 110.955 147.349 102.603 1.00 69.26  ? 413 PHE A CD2 1 
ATOM   2640  C CE1 . PHE A 1 404 ? 111.217 150.093 102.601 1.00 69.26  ? 413 PHE A CE1 1 
ATOM   2641  C CE2 . PHE A 1 404 ? 109.834 148.149 102.716 1.00 69.26  ? 413 PHE A CE2 1 
ATOM   2642  C CZ  . PHE A 1 404 ? 109.966 149.524 102.715 1.00 69.26  ? 413 PHE A CZ  1 
ATOM   2643  N N   . TYR A 1 405 ? 114.684 145.512 104.776 1.00 61.76  ? 414 TYR A N   1 
ATOM   2644  C CA  . TYR A 1 405 ? 114.605 144.826 106.060 1.00 61.76  ? 414 TYR A CA  1 
ATOM   2645  C C   . TYR A 1 405 ? 115.541 145.468 107.072 1.00 61.76  ? 414 TYR A C   1 
ATOM   2646  O O   . TYR A 1 405 ? 115.151 145.746 108.215 1.00 61.76  ? 414 TYR A O   1 
ATOM   2647  C CB  . TYR A 1 405 ? 114.937 143.344 105.858 1.00 61.76  ? 414 TYR A CB  1 
ATOM   2648  C CG  . TYR A 1 405 ? 115.138 142.528 107.116 1.00 61.76  ? 414 TYR A CG  1 
ATOM   2649  C CD1 . TYR A 1 405 ? 116.380 142.452 107.727 1.00 61.76  ? 414 TYR A CD1 1 
ATOM   2650  C CD2 . TYR A 1 405 ? 114.094 141.802 107.667 1.00 61.76  ? 414 TYR A CD2 1 
ATOM   2651  C CE1 . TYR A 1 405 ? 116.569 141.700 108.866 1.00 61.76  ? 414 TYR A CE1 1 
ATOM   2652  C CE2 . TYR A 1 405 ? 114.275 141.043 108.804 1.00 61.76  ? 414 TYR A CE2 1 
ATOM   2653  C CZ  . TYR A 1 405 ? 115.514 140.997 109.401 1.00 61.76  ? 414 TYR A CZ  1 
ATOM   2654  O OH  . TYR A 1 405 ? 115.703 140.244 110.537 1.00 61.76  ? 414 TYR A OH  1 
ATOM   2655  N N   . TRP A 1 406 ? 116.781 145.735 106.660 1.00 61.20  ? 415 TRP A N   1 
ATOM   2656  C CA  . TRP A 1 406 ? 117.752 146.310 107.578 1.00 61.20  ? 415 TRP A CA  1 
ATOM   2657  C C   . TRP A 1 406 ? 117.303 147.679 108.063 1.00 61.20  ? 415 TRP A C   1 
ATOM   2658  O O   . TRP A 1 406 ? 117.303 147.946 109.270 1.00 61.20  ? 415 TRP A O   1 
ATOM   2659  C CB  . TRP A 1 406 ? 119.120 146.391 106.905 1.00 61.20  ? 415 TRP A CB  1 
ATOM   2660  C CG  . TRP A 1 406 ? 120.234 145.906 107.772 1.00 61.20  ? 415 TRP A CG  1 
ATOM   2661  C CD1 . TRP A 1 406 ? 121.321 146.619 108.183 1.00 61.20  ? 415 TRP A CD1 1 
ATOM   2662  C CD2 . TRP A 1 406 ? 120.372 144.600 108.342 1.00 61.20  ? 415 TRP A CD2 1 
ATOM   2663  N NE1 . TRP A 1 406 ? 122.129 145.838 108.971 1.00 61.20  ? 415 TRP A NE1 1 
ATOM   2664  C CE2 . TRP A 1 406 ? 121.567 144.594 109.085 1.00 61.20  ? 415 TRP A CE2 1 
ATOM   2665  C CE3 . TRP A 1 406 ? 119.602 143.436 108.295 1.00 61.20  ? 415 TRP A CE3 1 
ATOM   2666  C CZ2 . TRP A 1 406 ? 122.009 143.470 109.774 1.00 61.20  ? 415 TRP A CZ2 1 
ATOM   2667  C CZ3 . TRP A 1 406 ? 120.042 142.324 108.981 1.00 61.20  ? 415 TRP A CZ3 1 
ATOM   2668  C CH2 . TRP A 1 406 ? 121.233 142.348 109.710 1.00 61.20  ? 415 TRP A CH2 1 
ATOM   2669  N N   . VAL A 1 407 ? 116.892 148.559 107.144 1.00 68.26  ? 416 VAL A N   1 
ATOM   2670  C CA  . VAL A 1 407 ? 116.527 149.905 107.569 1.00 68.26  ? 416 VAL A CA  1 
ATOM   2671  C C   . VAL A 1 407 ? 115.293 149.866 108.461 1.00 68.26  ? 416 VAL A C   1 
ATOM   2672  O O   . VAL A 1 407 ? 115.254 150.531 109.504 1.00 68.26  ? 416 VAL A O   1 
ATOM   2673  C CB  . VAL A 1 407 ? 116.332 150.849 106.364 1.00 68.26  ? 416 VAL A CB  1 
ATOM   2674  C CG1 . VAL A 1 407 ? 115.264 150.346 105.416 1.00 68.26  ? 416 VAL A CG1 1 
ATOM   2675  C CG2 . VAL A 1 407 ? 115.997 152.252 106.845 1.00 68.26  ? 416 VAL A CG2 1 
ATOM   2676  N N   . ILE A 1 408 ? 114.282 149.070 108.098 1.00 70.45  ? 417 ILE A N   1 
ATOM   2677  C CA  . ILE A 1 408 ? 113.051 149.074 108.881 1.00 70.45  ? 417 ILE A CA  1 
ATOM   2678  C C   . ILE A 1 408 ? 113.311 148.538 110.285 1.00 70.45  ? 417 ILE A C   1 
ATOM   2679  O O   . ILE A 1 408 ? 112.940 149.176 111.277 1.00 70.45  ? 417 ILE A O   1 
ATOM   2680  C CB  . ILE A 1 408 ? 111.927 148.306 108.154 1.00 70.45  ? 417 ILE A CB  1 
ATOM   2681  C CG1 . ILE A 1 408 ? 110.590 148.532 108.860 1.00 70.45  ? 417 ILE A CG1 1 
ATOM   2682  C CG2 . ILE A 1 408 ? 112.207 146.817 108.052 1.00 70.45  ? 417 ILE A CG2 1 
ATOM   2683  C CD1 . ILE A 1 408 ? 109.444 147.767 108.242 1.00 70.45  ? 417 ILE A CD1 1 
ATOM   2684  N N   . TYR A 1 409 ? 114.025 147.412 110.400 1.00 66.38  ? 418 TYR A N   1 
ATOM   2685  C CA  . TYR A 1 409 ? 114.221 146.806 111.710 1.00 66.38  ? 418 TYR A CA  1 
ATOM   2686  C C   . TYR A 1 409 ? 115.349 147.443 112.506 1.00 66.38  ? 418 TYR A C   1 
ATOM   2687  O O   . TYR A 1 409 ? 115.495 147.129 113.691 1.00 66.38  ? 418 TYR A O   1 
ATOM   2688  C CB  . TYR A 1 409 ? 114.482 145.306 111.569 1.00 66.38  ? 418 TYR A CB  1 
ATOM   2689  C CG  . TYR A 1 409 ? 113.234 144.466 111.677 1.00 66.38  ? 418 TYR A CG  1 
ATOM   2690  C CD1 . TYR A 1 409 ? 112.178 144.858 112.485 1.00 66.38  ? 418 TYR A CD1 1 
ATOM   2691  C CD2 . TYR A 1 409 ? 113.108 143.285 110.965 1.00 66.38  ? 418 TYR A CD2 1 
ATOM   2692  C CE1 . TYR A 1 409 ? 111.032 144.093 112.582 1.00 66.38  ? 418 TYR A CE1 1 
ATOM   2693  C CE2 . TYR A 1 409 ? 111.968 142.515 111.053 1.00 66.38  ? 418 TYR A CE2 1 
ATOM   2694  C CZ  . TYR A 1 409 ? 110.934 142.921 111.864 1.00 66.38  ? 418 TYR A CZ  1 
ATOM   2695  O OH  . TYR A 1 409 ? 109.798 142.153 111.954 1.00 66.38  ? 418 TYR A OH  1 
ATOM   2696  N N   . LYS A 1 410 ? 116.146 148.323 111.901 1.00 66.60  ? 419 LYS A N   1 
ATOM   2697  C CA  . LYS A 1 410 ? 117.188 149.013 112.643 1.00 66.60  ? 419 LYS A CA  1 
ATOM   2698  C C   . LYS A 1 410 ? 116.811 150.435 113.025 1.00 66.60  ? 419 LYS A C   1 
ATOM   2699  O O   . LYS A 1 410 ? 117.370 150.966 113.991 1.00 66.60  ? 419 LYS A O   1 
ATOM   2700  C CB  . LYS A 1 410 ? 118.488 149.035 111.830 1.00 66.60  ? 419 LYS A CB  1 
ATOM   2701  C CG  . LYS A 1 410 ? 119.744 149.216 112.663 1.00 66.60  ? 419 LYS A CG  1 
ATOM   2702  C CD  . LYS A 1 410 ? 120.803 148.190 112.296 1.00 66.60  ? 419 LYS A CD  1 
ATOM   2703  C CE  . LYS A 1 410 ? 122.065 148.378 113.123 1.00 66.60  ? 419 LYS A CE  1 
ATOM   2704  N NZ  . LYS A 1 410 ? 123.035 147.267 112.925 1.00 66.60  ? 419 LYS A NZ  1 
ATOM   2705  N N   . ILE A 1 411 ? 115.885 151.066 112.303 1.00 80.25  ? 420 ILE A N   1 
ATOM   2706  C CA  . ILE A 1 411 ? 115.500 152.436 112.613 1.00 80.25  ? 420 ILE A CA  1 
ATOM   2707  C C   . ILE A 1 411 ? 113.990 152.532 112.790 1.00 80.25  ? 420 ILE A C   1 
ATOM   2708  O O   . ILE A 1 411 ? 113.505 153.044 113.806 1.00 80.25  ? 420 ILE A O   1 
ATOM   2709  C CB  . ILE A 1 411 ? 115.986 153.405 111.519 1.00 80.25  ? 420 ILE A CB  1 
ATOM   2710  C CG1 . ILE A 1 411 ? 117.501 153.286 111.331 1.00 80.25  ? 420 ILE A CG1 1 
ATOM   2711  C CG2 . ILE A 1 411 ? 115.598 154.835 111.862 1.00 80.25  ? 420 ILE A CG2 1 
ATOM   2712  C CD1 . ILE A 1 411 ? 118.037 154.075 110.158 1.00 80.25  ? 420 ILE A CD1 1 
ATOM   2713  N N   . LEU A 1 412 ? 113.237 152.043 111.802 1.00 90.51  ? 421 LEU A N   1 
ATOM   2714  C CA  . LEU A 1 412 ? 111.810 152.346 111.754 1.00 90.51  ? 421 LEU A CA  1 
ATOM   2715  C C   . LEU A 1 412 ? 111.035 151.588 112.825 1.00 90.51  ? 421 LEU A C   1 
ATOM   2716  O O   . LEU A 1 412 ? 110.179 152.169 113.503 1.00 90.51  ? 421 LEU A O   1 
ATOM   2717  C CB  . LEU A 1 412 ? 111.255 152.032 110.366 1.00 90.51  ? 421 LEU A CB  1 
ATOM   2718  C CG  . LEU A 1 412 ? 111.848 152.834 109.205 1.00 90.51  ? 421 LEU A CG  1 
ATOM   2719  C CD1 . LEU A 1 412 ? 111.063 152.587 107.925 1.00 90.51  ? 421 LEU A CD1 1 
ATOM   2720  C CD2 . LEU A 1 412 ? 111.885 154.318 109.539 1.00 90.51  ? 421 LEU A CD2 1 
ATOM   2721  N N   . ARG A 1 413 ? 111.312 150.294 112.989 1.00 90.85  ? 422 ARG A N   1 
ATOM   2722  C CA  . ARG A 1 413 ? 110.530 149.487 113.921 1.00 90.85  ? 422 ARG A CA  1 
ATOM   2723  C C   . ARG A 1 413 ? 110.762 149.922 115.362 1.00 90.85  ? 422 ARG A C   1 
ATOM   2724  O O   . ARG A 1 413 ? 109.810 150.066 116.138 1.00 90.85  ? 422 ARG A O   1 
ATOM   2725  C CB  . ARG A 1 413 ? 110.859 148.006 113.739 1.00 90.85  ? 422 ARG A CB  1 
ATOM   2726  C CG  . ARG A 1 413 ? 109.830 147.059 114.342 1.00 90.85  ? 422 ARG A CG  1 
ATOM   2727  C CD  . ARG A 1 413 ? 108.401 147.539 114.117 1.00 90.85  ? 422 ARG A CD  1 
ATOM   2728  N NE  . ARG A 1 413 ? 108.097 147.766 112.709 1.00 90.85  ? 422 ARG A NE  1 
ATOM   2729  C CZ  . ARG A 1 413 ? 107.375 146.946 111.957 1.00 90.85  ? 422 ARG A CZ  1 
ATOM   2730  N NH1 . ARG A 1 413 ? 106.872 145.824 112.445 1.00 90.85  ? 422 ARG A NH1 1 
ATOM   2731  N NH2 . ARG A 1 413 ? 107.151 147.260 110.685 1.00 90.85  ? 422 ARG A NH2 1 
ATOM   2732  N N   . HIS A 1 414 ? 112.019 150.138 115.741 1.00 85.60  ? 423 HIS A N   1 
ATOM   2733  C CA  . HIS A 1 414 ? 112.357 150.608 117.077 1.00 85.60  ? 423 HIS A CA  1 
ATOM   2734  C C   . HIS A 1 414 ? 113.370 151.738 116.975 1.00 85.60  ? 423 HIS A C   1 
ATOM   2735  O O   . HIS A 1 414 ? 114.313 151.669 116.180 1.00 85.60  ? 423 HIS A O   1 
ATOM   2736  C CB  . HIS A 1 414 ? 112.899 149.465 117.955 1.00 85.60  ? 423 HIS A CB  1 
ATOM   2737  C CG  . HIS A 1 414 ? 114.382 149.276 117.870 1.00 85.60  ? 423 HIS A CG  1 
ATOM   2738  N ND1 . HIS A 1 414 ? 114.978 148.484 116.912 1.00 85.60  ? 423 HIS A ND1 1 
ATOM   2739  C CD2 . HIS A 1 414 ? 115.389 149.767 118.630 1.00 85.60  ? 423 HIS A CD2 1 
ATOM   2740  C CE1 . HIS A 1 414 ? 116.288 148.500 117.082 1.00 85.60  ? 423 HIS A CE1 1 
ATOM   2741  N NE2 . HIS A 1 414 ? 116.564 149.272 118.118 1.00 85.60  ? 423 HIS A NE2 1 
ATOM   2742  N N   . GLU A 1 415 ? 113.158 152.779 117.778 1.00 83.82  ? 424 GLU A N   1 
ATOM   2743  C CA  . GLU A 1 415 ? 114.033 153.949 117.814 1.00 83.82  ? 424 GLU A CA  1 
ATOM   2744  C C   . GLU A 1 415 ? 114.242 154.547 116.425 1.00 83.82  ? 424 GLU A C   1 
ATOM   2745  O O   . GLU A 1 415 ? 114.319 155.765 116.269 1.00 83.82  ? 424 GLU A O   1 
ATOM   2746  C CB  . GLU A 1 415 ? 115.384 153.591 118.439 1.00 83.82  ? 424 GLU A CB  1 
ATOM   2747  C CG  . GLU A 1 415 ? 116.306 154.781 118.652 1.00 83.82  ? 424 GLU A CG  1 
ATOM   2748  C CD  . GLU A 1 415 ? 117.410 154.857 117.619 1.00 83.82  ? 424 GLU A CD  1 
ATOM   2749  O OE1 . GLU A 1 415 ? 118.056 153.821 117.359 1.00 83.82  ? 424 GLU A OE1 1 
ATOM   2750  O OE2 . GLU A 1 415 ? 117.631 155.954 117.065 1.00 83.82  ? 424 GLU A OE2 1 
ATOM   2751  N N   . MET B 1 8   ? 98.262  147.524 179.871 1.00 96.70  ? 8   MET B N   1 
ATOM   2752  C CA  . MET B 1 8   ? 98.065  148.672 178.995 1.00 96.70  ? 8   MET B CA  1 
ATOM   2753  C C   . MET B 1 8   ? 99.118  148.695 177.893 1.00 96.70  ? 8   MET B C   1 
ATOM   2754  O O   . MET B 1 8   ? 98.872  149.196 176.796 1.00 96.70  ? 8   MET B O   1 
ATOM   2755  C CB  . MET B 1 8   ? 98.104  149.975 179.799 1.00 96.70  ? 8   MET B CB  1 
ATOM   2756  C CG  . MET B 1 8   ? 99.423  150.238 180.508 1.00 96.70  ? 8   MET B CG  1 
ATOM   2757  S SD  . MET B 1 8   ? 99.948  148.861 181.547 1.00 96.70  ? 8   MET B SD  1 
ATOM   2758  C CE  . MET B 1 8   ? 98.741  148.950 182.865 1.00 96.70  ? 8   MET B CE  1 
ATOM   2759  N N   . SER B 1 9   ? 100.292 148.151 178.193 1.00 85.33  ? 9   SER B N   1 
ATOM   2760  C CA  . SER B 1 9   ? 101.342 148.064 177.192 1.00 85.33  ? 9   SER B CA  1 
ATOM   2761  C C   . SER B 1 9   ? 100.943 147.066 176.108 1.00 85.33  ? 9   SER B C   1 
ATOM   2762  O O   . SER B 1 9   ? 100.345 146.029 176.409 1.00 85.33  ? 9   SER B O   1 
ATOM   2763  C CB  . SER B 1 9   ? 102.661 147.643 177.835 1.00 85.33  ? 9   SER B CB  1 
ATOM   2764  O OG  . SER B 1 9   ? 103.685 147.517 176.865 1.00 85.33  ? 9   SER B OG  1 
ATOM   2765  N N   . PRO B 1 10  ? 101.248 147.352 174.841 1.00 73.44  ? 10  PRO B N   1 
ATOM   2766  C CA  . PRO B 1 10  ? 100.887 146.405 173.774 1.00 73.44  ? 10  PRO B CA  1 
ATOM   2767  C C   . PRO B 1 10  ? 101.525 145.038 173.939 1.00 73.44  ? 10  PRO B C   1 
ATOM   2768  O O   . PRO B 1 10  ? 100.906 144.029 173.578 1.00 73.44  ? 10  PRO B O   1 
ATOM   2769  C CB  . PRO B 1 10  ? 101.372 147.112 172.501 1.00 73.44  ? 10  PRO B CB  1 
ATOM   2770  C CG  . PRO B 1 10  ? 102.401 148.090 172.971 1.00 73.44  ? 10  PRO B CG  1 
ATOM   2771  C CD  . PRO B 1 10  ? 101.944 148.540 174.320 1.00 73.44  ? 10  PRO B CD  1 
ATOM   2772  N N   . SER B 1 11  ? 102.745 144.972 174.477 1.00 70.93  ? 11  SER B N   1 
ATOM   2773  C CA  . SER B 1 11  ? 103.354 143.677 174.762 1.00 70.93  ? 11  SER B CA  1 
ATOM   2774  C C   . SER B 1 11  ? 102.551 142.916 175.806 1.00 70.93  ? 11  SER B C   1 
ATOM   2775  O O   . SER B 1 11  ? 102.382 141.695 175.704 1.00 70.93  ? 11  SER B O   1 
ATOM   2776  C CB  . SER B 1 11  ? 104.797 143.863 175.228 1.00 70.93  ? 11  SER B CB  1 
ATOM   2777  O OG  . SER B 1 11  ? 105.644 144.206 174.146 1.00 70.93  ? 11  SER B OG  1 
ATOM   2778  N N   . ASP B 1 12  ? 102.048 143.624 176.819 1.00 73.89  ? 12  ASP B N   1 
ATOM   2779  C CA  . ASP B 1 12  ? 101.196 142.990 177.819 1.00 73.89  ? 12  ASP B CA  1 
ATOM   2780  C C   . ASP B 1 12  ? 99.944  142.416 177.169 1.00 73.89  ? 12  ASP B C   1 
ATOM   2781  O O   . ASP B 1 12  ? 99.538  141.289 177.476 1.00 73.89  ? 12  ASP B O   1 
ATOM   2782  C CB  . ASP B 1 12  ? 100.851 144.010 178.911 1.00 73.89  ? 12  ASP B CB  1 
ATOM   2783  C CG  . ASP B 1 12  ? 99.878  143.475 179.962 1.00 73.89  ? 12  ASP B CG  1 
ATOM   2784  O OD1 . ASP B 1 12  ? 98.812  142.923 179.617 1.00 73.89  ? 12  ASP B OD1 1 
ATOM   2785  O OD2 . ASP B 1 12  ? 100.189 143.618 181.162 1.00 73.89  ? 12  ASP B OD2 1 
ATOM   2786  N N   . PHE B 1 13  ? 99.325  143.172 176.260 1.00 71.83  ? 13  PHE B N   1 
ATOM   2787  C CA  . PHE B 1 13  ? 98.128  142.685 175.583 1.00 71.83  ? 13  PHE B CA  1 
ATOM   2788  C C   . PHE B 1 13  ? 98.432  141.462 174.727 1.00 71.83  ? 13  PHE B C   1 
ATOM   2789  O O   . PHE B 1 13  ? 97.674  140.484 174.738 1.00 71.83  ? 13  PHE B O   1 
ATOM   2790  C CB  . PHE B 1 13  ? 97.524  143.799 174.733 1.00 71.83  ? 13  PHE B CB  1 
ATOM   2791  C CG  . PHE B 1 13  ? 96.525  143.318 173.726 1.00 71.83  ? 13  PHE B CG  1 
ATOM   2792  C CD1 . PHE B 1 13  ? 95.380  142.656 174.129 1.00 71.83  ? 13  PHE B CD1 1 
ATOM   2793  C CD2 . PHE B 1 13  ? 96.730  143.532 172.375 1.00 71.83  ? 13  PHE B CD2 1 
ATOM   2794  C CE1 . PHE B 1 13  ? 94.460  142.214 173.203 1.00 71.83  ? 13  PHE B CE1 1 
ATOM   2795  C CE2 . PHE B 1 13  ? 95.814  143.094 171.445 1.00 71.83  ? 13  PHE B CE2 1 
ATOM   2796  C CZ  . PHE B 1 13  ? 94.677  142.434 171.859 1.00 71.83  ? 13  PHE B CZ  1 
ATOM   2797  N N   . LEU B 1 14  ? 99.536  141.497 173.978 1.00 62.97  ? 14  LEU B N   1 
ATOM   2798  C CA  . LEU B 1 14  ? 99.893  140.355 173.141 1.00 62.97  ? 14  LEU B CA  1 
ATOM   2799  C C   . LEU B 1 14  ? 100.168 139.118 173.984 1.00 62.97  ? 14  LEU B C   1 
ATOM   2800  O O   . LEU B 1 14  ? 99.756  138.009 173.625 1.00 62.97  ? 14  LEU B O   1 
ATOM   2801  C CB  . LEU B 1 14  ? 101.103 140.694 172.274 1.00 62.97  ? 14  LEU B CB  1 
ATOM   2802  C CG  . LEU B 1 14  ? 100.820 140.922 170.789 1.00 62.97  ? 14  LEU B CG  1 
ATOM   2803  C CD1 . LEU B 1 14  ? 100.007 142.187 170.589 1.00 62.97  ? 14  LEU B CD1 1 
ATOM   2804  C CD2 . LEU B 1 14  ? 102.116 140.987 170.000 1.00 62.97  ? 14  LEU B CD2 1 
ATOM   2805  N N   . ASP B 1 15  ? 100.866 139.284 175.109 1.00 68.51  ? 15  ASP B N   1 
ATOM   2806  C CA  . ASP B 1 15  ? 101.129 138.146 175.983 1.00 68.51  ? 15  ASP B CA  1 
ATOM   2807  C C   . ASP B 1 15  ? 99.842  137.616 176.601 1.00 68.51  ? 15  ASP B C   1 
ATOM   2808  O O   . ASP B 1 15  ? 99.674  136.401 176.751 1.00 68.51  ? 15  ASP B O   1 
ATOM   2809  C CB  . ASP B 1 15  ? 102.129 138.538 177.069 1.00 68.51  ? 15  ASP B CB  1 
ATOM   2810  C CG  . ASP B 1 15  ? 103.080 137.411 177.419 1.00 68.51  ? 15  ASP B CG  1 
ATOM   2811  O OD1 . ASP B 1 15  ? 102.654 136.237 177.382 1.00 68.51  ? 15  ASP B OD1 1 
ATOM   2812  O OD2 . ASP B 1 15  ? 104.255 137.698 177.729 1.00 68.51  ? 15  ASP B OD2 1 
ATOM   2813  N N   . LYS B 1 16  ? 98.925  138.510 176.973 1.00 62.16  ? 16  LYS B N   1 
ATOM   2814  C CA  . LYS B 1 16  ? 97.664  138.072 177.559 1.00 62.16  ? 16  LYS B CA  1 
ATOM   2815  C C   . LYS B 1 16  ? 96.785  137.367 176.534 1.00 62.16  ? 16  LYS B C   1 
ATOM   2816  O O   . LYS B 1 16  ? 95.987  136.496 176.898 1.00 62.16  ? 16  LYS B O   1 
ATOM   2817  C CB  . LYS B 1 16  ? 96.937  139.272 178.171 1.00 62.16  ? 16  LYS B CB  1 
ATOM   2818  C CG  . LYS B 1 16  ? 95.464  139.052 178.483 1.00 62.16  ? 16  LYS B CG  1 
ATOM   2819  C CD  . LYS B 1 16  ? 94.577  139.802 177.501 1.00 62.16  ? 16  LYS B CD  1 
ATOM   2820  C CE  . LYS B 1 16  ? 93.104  139.550 177.776 1.00 62.16  ? 16  LYS B CE  1 
ATOM   2821  N NZ  . LYS B 1 16  ? 92.231  140.247 176.792 1.00 62.16  ? 16  LYS B NZ  1 
ATOM   2822  N N   . LEU B 1 17  ? 96.923  137.711 175.254 1.00 59.40  ? 17  LEU B N   1 
ATOM   2823  C CA  . LEU B 1 17  ? 96.048  137.135 174.238 1.00 59.40  ? 17  LEU B CA  1 
ATOM   2824  C C   . LEU B 1 17  ? 96.492  135.730 173.842 1.00 59.40  ? 17  LEU B C   1 
ATOM   2825  O O   . LEU B 1 17  ? 95.740  134.764 174.000 1.00 59.40  ? 17  LEU B O   1 
ATOM   2826  C CB  . LEU B 1 17  ? 95.994  138.048 173.013 1.00 59.40  ? 17  LEU B CB  1 
ATOM   2827  C CG  . LEU B 1 17  ? 94.872  137.736 172.026 1.00 59.40  ? 17  LEU B CG  1 
ATOM   2828  C CD1 . LEU B 1 17  ? 93.583  137.438 172.770 1.00 59.40  ? 17  LEU B CD1 1 
ATOM   2829  C CD2 . LEU B 1 17  ? 94.684  138.894 171.064 1.00 59.40  ? 17  LEU B CD2 1 
ATOM   2830  N N   . MET B 1 18  ? 97.714  135.597 173.320 1.00 62.02  ? 18  MET B N   1 
ATOM   2831  C CA  . MET B 1 18  ? 98.215  134.305 172.866 1.00 62.02  ? 18  MET B CA  1 
ATOM   2832  C C   . MET B 1 18  ? 99.601  133.982 173.411 1.00 62.02  ? 18  MET B C   1 
ATOM   2833  O O   . MET B 1 18  ? 100.209 132.997 172.975 1.00 62.02  ? 18  MET B O   1 
ATOM   2834  C CB  . MET B 1 18  ? 98.246  134.242 171.333 1.00 62.02  ? 18  MET B CB  1 
ATOM   2835  C CG  . MET B 1 18  ? 99.375  135.037 170.698 1.00 62.02  ? 18  MET B CG  1 
ATOM   2836  S SD  . MET B 1 18  ? 98.905  135.847 169.160 1.00 62.02  ? 18  MET B SD  1 
ATOM   2837  C CE  . MET B 1 18  ? 97.557  136.880 169.719 1.00 62.02  ? 18  MET B CE  1 
ATOM   2838  N N   . GLY B 1 19  ? 100.112 134.768 174.353 1.00 67.95  ? 19  GLY B N   1 
ATOM   2839  C CA  . GLY B 1 19  ? 101.452 134.579 174.860 1.00 67.95  ? 19  GLY B CA  1 
ATOM   2840  C C   . GLY B 1 19  ? 101.535 133.478 175.901 1.00 67.95  ? 19  GLY B C   1 
ATOM   2841  O O   . GLY B 1 19  ? 100.638 132.649 176.061 1.00 67.95  ? 19  GLY B O   1 
ATOM   2842  N N   . ARG B 1 20  ? 102.660 133.478 176.620 1.00 74.40  ? 20  ARG B N   1 
ATOM   2843  C CA  . ARG B 1 20  ? 102.895 132.452 177.632 1.00 74.40  ? 20  ARG B CA  1 
ATOM   2844  C C   . ARG B 1 20  ? 101.871 132.532 178.756 1.00 74.40  ? 20  ARG B C   1 
ATOM   2845  O O   . ARG B 1 20  ? 101.351 131.504 179.206 1.00 74.40  ? 20  ARG B O   1 
ATOM   2846  C CB  . ARG B 1 20  ? 104.313 132.583 178.188 1.00 74.40  ? 20  ARG B CB  1 
ATOM   2847  N N   . THR B 1 21  ? 101.562 133.743 179.219 1.00 71.59  ? 21  THR B N   1 
ATOM   2848  C CA  . THR B 1 21  ? 100.605 133.917 180.302 1.00 71.59  ? 21  THR B CA  1 
ATOM   2849  C C   . THR B 1 21  ? 99.160  133.887 179.826 1.00 71.59  ? 21  THR B C   1 
ATOM   2850  O O   . THR B 1 21  ? 98.249  133.973 180.656 1.00 71.59  ? 21  THR B O   1 
ATOM   2851  C CB  . THR B 1 21  ? 100.868 135.234 181.035 1.00 71.59  ? 21  THR B CB  1 
ATOM   2852  O OG1 . THR B 1 21  ? 100.104 135.269 182.247 1.00 71.59  ? 21  THR B OG1 1 
ATOM   2853  C CG2 . THR B 1 21  ? 100.473 136.415 180.162 1.00 71.59  ? 21  THR B CG2 1 
ATOM   2854  N N   . SER B 1 22  ? 98.931  133.779 178.516 1.00 63.04  ? 22  SER B N   1 
ATOM   2855  C CA  . SER B 1 22  ? 97.569  133.750 177.998 1.00 63.04  ? 22  SER B CA  1 
ATOM   2856  C C   . SER B 1 22  ? 96.823  132.502 178.452 1.00 63.04  ? 22  SER B C   1 
ATOM   2857  O O   . SER B 1 22  ? 95.638  132.571 178.795 1.00 63.04  ? 22  SER B O   1 
ATOM   2858  C CB  . SER B 1 22  ? 97.592  133.825 176.473 1.00 63.04  ? 22  SER B CB  1 
ATOM   2859  O OG  . SER B 1 22  ? 98.308  132.735 175.923 1.00 63.04  ? 22  SER B OG  1 
ATOM   2860  N N   . GLY B 1 23  ? 97.497  131.357 178.459 1.00 61.48  ? 23  GLY B N   1 
ATOM   2861  C CA  . GLY B 1 23  ? 96.840  130.088 178.672 1.00 61.48  ? 23  GLY B CA  1 
ATOM   2862  C C   . GLY B 1 23  ? 96.264  129.471 177.418 1.00 61.48  ? 23  GLY B C   1 
ATOM   2863  O O   . GLY B 1 23  ? 95.758  128.343 177.477 1.00 61.48  ? 23  GLY B O   1 
ATOM   2864  N N   . TYR B 1 24  ? 96.324  130.174 176.291 1.00 52.25  ? 24  TYR B N   1 
ATOM   2865  C CA  . TYR B 1 24  ? 95.841  129.633 175.030 1.00 52.25  ? 24  TYR B CA  1 
ATOM   2866  C C   . TYR B 1 24  ? 96.759  128.510 174.565 1.00 52.25  ? 24  TYR B C   1 
ATOM   2867  O O   . TYR B 1 24  ? 97.982  128.672 174.518 1.00 52.25  ? 24  TYR B O   1 
ATOM   2868  C CB  . TYR B 1 24  ? 95.771  130.747 173.984 1.00 52.25  ? 24  TYR B CB  1 
ATOM   2869  C CG  . TYR B 1 24  ? 95.676  130.278 172.552 1.00 52.25  ? 24  TYR B CG  1 
ATOM   2870  C CD1 . TYR B 1 24  ? 94.466  129.862 172.017 1.00 52.25  ? 24  TYR B CD1 1 
ATOM   2871  C CD2 . TYR B 1 24  ? 96.792  130.271 171.729 1.00 52.25  ? 24  TYR B CD2 1 
ATOM   2872  C CE1 . TYR B 1 24  ? 94.372  129.440 170.706 1.00 52.25  ? 24  TYR B CE1 1 
ATOM   2873  C CE2 . TYR B 1 24  ? 96.708  129.850 170.418 1.00 52.25  ? 24  TYR B CE2 1 
ATOM   2874  C CZ  . TYR B 1 24  ? 95.496  129.436 169.912 1.00 52.25  ? 24  TYR B CZ  1 
ATOM   2875  O OH  . TYR B 1 24  ? 95.407  129.016 168.606 1.00 52.25  ? 24  TYR B OH  1 
ATOM   2876  N N   . ASP B 1 25  ? 96.168  127.370 174.223 1.00 53.83  ? 25  ASP B N   1 
ATOM   2877  C CA  . ASP B 1 25  ? 96.912  126.184 173.812 1.00 53.83  ? 25  ASP B CA  1 
ATOM   2878  C C   . ASP B 1 25  ? 96.721  125.999 172.313 1.00 53.83  ? 25  ASP B C   1 
ATOM   2879  O O   . ASP B 1 25  ? 95.633  125.628 171.861 1.00 53.83  ? 25  ASP B O   1 
ATOM   2880  C CB  . ASP B 1 25  ? 96.443  124.954 174.586 1.00 53.83  ? 25  ASP B CB  1 
ATOM   2881  C CG  . ASP B 1 25  ? 97.491  123.863 174.635 1.00 53.83  ? 25  ASP B CG  1 
ATOM   2882  O OD1 . ASP B 1 25  ? 98.380  123.851 173.758 1.00 53.83  ? 25  ASP B OD1 1 
ATOM   2883  O OD2 . ASP B 1 25  ? 97.426  123.016 175.550 1.00 53.83  ? 25  ASP B OD2 1 
ATOM   2884  N N   . ALA B 1 26  ? 97.781  126.251 171.544 1.00 46.69  ? 26  ALA B N   1 
ATOM   2885  C CA  . ALA B 1 26  ? 97.693  126.170 170.092 1.00 46.69  ? 26  ALA B CA  1 
ATOM   2886  C C   . ALA B 1 26  ? 97.609  124.740 169.579 1.00 46.69  ? 26  ALA B C   1 
ATOM   2887  O O   . ALA B 1 26  ? 97.320  124.543 168.395 1.00 46.69  ? 26  ALA B O   1 
ATOM   2888  C CB  . ALA B 1 26  ? 98.891  126.873 169.455 1.00 46.69  ? 26  ALA B CB  1 
ATOM   2889  N N   . ARG B 1 27  ? 97.850  123.747 170.427 1.00 45.95  ? 27  ARG B N   1 
ATOM   2890  C CA  . ARG B 1 27  ? 97.830  122.353 170.015 1.00 45.95  ? 27  ARG B CA  1 
ATOM   2891  C C   . ARG B 1 27  ? 96.436  121.745 170.053 1.00 45.95  ? 27  ARG B C   1 
ATOM   2892  O O   . ARG B 1 27  ? 96.283  120.562 169.732 1.00 45.95  ? 27  ARG B O   1 
ATOM   2893  C CB  . ARG B 1 27  ? 98.769  121.534 170.902 1.00 45.95  ? 27  ARG B CB  1 
ATOM   2894  C CG  . ARG B 1 27  ? 100.242 121.812 170.668 1.00 45.95  ? 27  ARG B CG  1 
ATOM   2895  C CD  . ARG B 1 27  ? 101.116 121.007 171.613 1.00 45.95  ? 27  ARG B CD  1 
ATOM   2896  N NE  . ARG B 1 27  ? 100.832 121.304 173.012 1.00 45.95  ? 27  ARG B NE  1 
ATOM   2897  C CZ  . ARG B 1 27  ? 100.106 120.533 173.810 1.00 45.95  ? 27  ARG B CZ  1 
ATOM   2898  N NH1 . ARG B 1 27  ? 99.573  119.402 173.379 1.00 45.95  ? 27  ARG B NH1 1 
ATOM   2899  N NH2 . ARG B 1 27  ? 99.908  120.907 175.071 1.00 45.95  ? 27  ARG B NH2 1 
ATOM   2900  N N   . ILE B 1 28  ? 95.424  122.516 170.437 1.00 48.05  ? 28  ILE B N   1 
ATOM   2901  C CA  . ILE B 1 28  ? 94.062  122.022 170.590 1.00 48.05  ? 28  ILE B CA  1 
ATOM   2902  C C   . ILE B 1 28  ? 93.170  122.747 169.594 1.00 48.05  ? 28  ILE B C   1 
ATOM   2903  O O   . ILE B 1 28  ? 93.176  123.981 169.530 1.00 48.05  ? 28  ILE B O   1 
ATOM   2904  C CB  . ILE B 1 28  ? 93.551  122.215 172.028 1.00 48.05  ? 28  ILE B CB  1 
ATOM   2905  C CG1 . ILE B 1 28  ? 94.359  121.349 172.992 1.00 48.05  ? 28  ILE B CG1 1 
ATOM   2906  C CG2 . ILE B 1 28  ? 92.077  121.877 172.118 1.00 48.05  ? 28  ILE B CG2 1 
ATOM   2907  C CD1 . ILE B 1 28  ? 94.053  121.614 174.441 1.00 48.05  ? 28  ILE B CD1 1 
ATOM   2908  N N   . ARG B 1 29  ? 92.407  121.979 168.828 1.00 46.35  ? 29  ARG B N   1 
ATOM   2909  C CA  . ARG B 1 29  ? 91.539  122.552 167.813 1.00 46.35  ? 29  ARG B CA  1 
ATOM   2910  C C   . ARG B 1 29  ? 90.490  123.449 168.466 1.00 46.35  ? 29  ARG B C   1 
ATOM   2911  O O   . ARG B 1 29  ? 89.959  123.110 169.530 1.00 46.35  ? 29  ARG B O   1 
ATOM   2912  C CB  . ARG B 1 29  ? 90.860  121.433 167.021 1.00 46.35  ? 29  ARG B CB  1 
ATOM   2913  C CG  . ARG B 1 29  ? 89.972  121.895 165.887 1.00 46.35  ? 29  ARG B CG  1 
ATOM   2914  C CD  . ARG B 1 29  ? 88.879  120.883 165.611 1.00 46.35  ? 29  ARG B CD  1 
ATOM   2915  N NE  . ARG B 1 29  ? 87.823  120.950 166.612 1.00 46.35  ? 29  ARG B NE  1 
ATOM   2916  C CZ  . ARG B 1 29  ? 86.844  120.065 166.726 1.00 46.35  ? 29  ARG B CZ  1 
ATOM   2917  N NH1 . ARG B 1 29  ? 86.761  119.021 165.920 1.00 46.35  ? 29  ARG B NH1 1 
ATOM   2918  N NH2 . ARG B 1 29  ? 85.925  120.231 167.672 1.00 46.35  ? 29  ARG B NH2 1 
ATOM   2919  N N   . PRO B 1 30  ? 90.180  124.603 167.874 1.00 44.98  ? 30  PRO B N   1 
ATOM   2920  C CA  . PRO B 1 30  ? 89.096  125.434 168.407 1.00 44.98  ? 30  PRO B CA  1 
ATOM   2921  C C   . PRO B 1 30  ? 87.767  124.697 168.359 1.00 44.98  ? 30  PRO B C   1 
ATOM   2922  O O   . PRO B 1 30  ? 87.522  123.874 167.475 1.00 44.98  ? 30  PRO B O   1 
ATOM   2923  C CB  . PRO B 1 30  ? 89.093  126.655 167.481 1.00 44.98  ? 30  PRO B CB  1 
ATOM   2924  C CG  . PRO B 1 30  ? 89.780  126.193 166.241 1.00 44.98  ? 30  PRO B CG  1 
ATOM   2925  C CD  . PRO B 1 30  ? 90.818  125.222 166.703 1.00 44.98  ? 30  PRO B CD  1 
ATOM   2926  N N   . ASN B 1 31  ? 86.905  125.008 169.327 1.00 49.90  ? 31  ASN B N   1 
ATOM   2927  C CA  . ASN B 1 31  ? 85.633  124.310 169.507 1.00 49.90  ? 31  ASN B CA  1 
ATOM   2928  C C   . ASN B 1 31  ? 85.860  122.806 169.642 1.00 49.90  ? 31  ASN B C   1 
ATOM   2929  O O   . ASN B 1 31  ? 85.217  121.991 168.978 1.00 49.90  ? 31  ASN B O   1 
ATOM   2930  C CB  . ASN B 1 31  ? 84.663  124.616 168.364 1.00 49.90  ? 31  ASN B CB  1 
ATOM   2931  C CG  . ASN B 1 31  ? 84.680  126.073 167.957 1.00 49.90  ? 31  ASN B CG  1 
ATOM   2932  O OD1 . ASN B 1 31  ? 85.622  126.541 167.318 1.00 49.90  ? 31  ASN B OD1 1 
ATOM   2933  N ND2 . ASN B 1 31  ? 83.629  126.798 168.317 1.00 49.90  ? 31  ASN B ND2 1 
ATOM   2934  N N   . PHE B 1 32  ? 86.800  122.443 170.512 1.00 54.37  ? 32  PHE B N   1 
ATOM   2935  C CA  . PHE B 1 32  ? 87.175  121.045 170.667 1.00 54.37  ? 32  PHE B CA  1 
ATOM   2936  C C   . PHE B 1 32  ? 86.002  120.219 171.177 1.00 54.37  ? 32  PHE B C   1 
ATOM   2937  O O   . PHE B 1 32  ? 85.215  120.674 172.011 1.00 54.37  ? 32  PHE B O   1 
ATOM   2938  C CB  . PHE B 1 32  ? 88.360  120.916 171.621 1.00 54.37  ? 32  PHE B CB  1 
ATOM   2939  C CG  . PHE B 1 32  ? 89.023  119.571 171.579 1.00 54.37  ? 32  PHE B CG  1 
ATOM   2940  C CD1 . PHE B 1 32  ? 89.633  119.122 170.422 1.00 54.37  ? 32  PHE B CD1 1 
ATOM   2941  C CD2 . PHE B 1 32  ? 89.039  118.758 172.696 1.00 54.37  ? 32  PHE B CD2 1 
ATOM   2942  C CE1 . PHE B 1 32  ? 90.245  117.886 170.379 1.00 54.37  ? 32  PHE B CE1 1 
ATOM   2943  C CE2 . PHE B 1 32  ? 89.649  117.522 172.660 1.00 54.37  ? 32  PHE B CE2 1 
ATOM   2944  C CZ  . PHE B 1 32  ? 90.253  117.085 171.499 1.00 54.37  ? 32  PHE B CZ  1 
ATOM   2945  N N   . LYS B 1 33  ? 85.897  118.992 170.663 1.00 62.69  ? 33  LYS B N   1 
ATOM   2946  C CA  . LYS B 1 33  ? 84.829  118.062 171.029 1.00 62.69  ? 33  LYS B CA  1 
ATOM   2947  C C   . LYS B 1 33  ? 83.454  118.693 170.827 1.00 62.69  ? 33  LYS B C   1 
ATOM   2948  O O   . LYS B 1 33  ? 82.563  118.588 171.672 1.00 62.69  ? 33  LYS B O   1 
ATOM   2949  C CB  . LYS B 1 33  ? 85.001  117.565 172.465 1.00 62.69  ? 33  LYS B CB  1 
ATOM   2950  C CG  . LYS B 1 33  ? 84.503  116.147 172.689 1.00 62.69  ? 33  LYS B CG  1 
ATOM   2951  C CD  . LYS B 1 33  ? 85.141  115.174 171.708 1.00 62.69  ? 33  LYS B CD  1 
ATOM   2952  C CE  . LYS B 1 33  ? 86.641  115.071 171.923 1.00 62.69  ? 33  LYS B CE  1 
ATOM   2953  N NZ  . LYS B 1 33  ? 86.971  114.712 173.327 1.00 62.69  ? 33  LYS B NZ  1 
ATOM   2954  N N   . GLY B 1 34  ? 83.286  119.362 169.691 1.00 55.21  ? 34  GLY B N   1 
ATOM   2955  C CA  . GLY B 1 34  ? 82.031  119.982 169.348 1.00 55.21  ? 34  GLY B CA  1 
ATOM   2956  C C   . GLY B 1 34  ? 81.833  120.045 167.849 1.00 55.21  ? 34  GLY B C   1 
ATOM   2957  O O   . GLY B 1 34  ? 82.242  119.146 167.107 1.00 55.21  ? 34  GLY B O   1 
ATOM   2958  N N   . PRO B 1 35  ? 81.191  121.113 167.372 1.00 51.40  ? 35  PRO B N   1 
ATOM   2959  C CA  . PRO B 1 35  ? 81.006  121.264 165.933 1.00 51.40  ? 35  PRO B CA  1 
ATOM   2960  C C   . PRO B 1 35  ? 82.341  121.442 165.236 1.00 51.40  ? 35  PRO B C   1 
ATOM   2961  O O   . PRO B 1 35  ? 83.294  121.989 165.818 1.00 51.40  ? 35  PRO B O   1 
ATOM   2962  C CB  . PRO B 1 35  ? 80.140  122.532 165.819 1.00 51.40  ? 35  PRO B CB  1 
ATOM   2963  C CG  . PRO B 1 35  ? 80.400  123.277 167.079 1.00 51.40  ? 35  PRO B CG  1 
ATOM   2964  C CD  . PRO B 1 35  ? 80.613  122.233 168.131 1.00 51.40  ? 35  PRO B CD  1 
ATOM   2965  N N   . PRO B 1 36  ? 82.466  120.986 163.993 1.00 44.60  ? 36  PRO B N   1 
ATOM   2966  C CA  . PRO B 1 36  ? 83.728  121.161 163.271 1.00 44.60  ? 36  PRO B CA  1 
ATOM   2967  C C   . PRO B 1 36  ? 84.006  122.627 162.992 1.00 44.60  ? 36  PRO B C   1 
ATOM   2968  O O   . PRO B 1 36  ? 83.092  123.432 162.800 1.00 44.60  ? 36  PRO B O   1 
ATOM   2969  C CB  . PRO B 1 36  ? 83.502  120.383 161.971 1.00 44.60  ? 36  PRO B CB  1 
ATOM   2970  C CG  . PRO B 1 36  ? 82.029  120.408 161.780 1.00 44.60  ? 36  PRO B CG  1 
ATOM   2971  C CD  . PRO B 1 36  ? 81.437  120.342 163.159 1.00 44.60  ? 36  PRO B CD  1 
ATOM   2972  N N   . VAL B 1 37  ? 85.294  122.971 162.972 1.00 42.06  ? 37  VAL B N   1 
ATOM   2973  C CA  . VAL B 1 37  ? 85.683  124.340 162.664 1.00 42.06  ? 37  VAL B CA  1 
ATOM   2974  C C   . VAL B 1 37  ? 85.354  124.638 161.207 1.00 42.06  ? 37  VAL B C   1 
ATOM   2975  O O   . VAL B 1 37  ? 85.232  123.732 160.371 1.00 42.06  ? 37  VAL B O   1 
ATOM   2976  C CB  . VAL B 1 37  ? 87.174  124.574 162.966 1.00 42.06  ? 37  VAL B CB  1 
ATOM   2977  C CG1 . VAL B 1 37  ? 88.026  124.193 161.779 1.00 42.06  ? 37  VAL B CG1 1 
ATOM   2978  C CG2 . VAL B 1 37  ? 87.413  126.019 163.353 1.00 42.06  ? 37  VAL B CG2 1 
ATOM   2979  N N   . ASN B 1 38  ? 85.194  125.919 160.899 1.00 38.71  ? 38  ASN B N   1 
ATOM   2980  C CA  . ASN B 1 38  ? 84.680  126.364 159.609 1.00 38.71  ? 38  ASN B CA  1 
ATOM   2981  C C   . ASN B 1 38  ? 85.705  127.298 158.982 1.00 38.71  ? 38  ASN B C   1 
ATOM   2982  O O   . ASN B 1 38  ? 85.898  128.422 159.456 1.00 38.71  ? 38  ASN B O   1 
ATOM   2983  C CB  . ASN B 1 38  ? 83.332  127.057 159.794 1.00 38.71  ? 38  ASN B CB  1 
ATOM   2984  C CG  . ASN B 1 38  ? 82.449  126.969 158.571 1.00 38.71  ? 38  ASN B CG  1 
ATOM   2985  O OD1 . ASN B 1 38  ? 82.747  127.575 157.543 1.00 38.71  ? 38  ASN B OD1 1 
ATOM   2986  N ND2 . ASN B 1 38  ? 81.346  126.224 158.670 1.00 38.71  ? 38  ASN B ND2 1 
ATOM   2987  N N   . VAL B 1 39  ? 86.355  126.840 157.916 1.00 32.93  ? 39  VAL B N   1 
ATOM   2988  C CA  . VAL B 1 39  ? 87.436  127.576 157.270 1.00 32.93  ? 39  VAL B CA  1 
ATOM   2989  C C   . VAL B 1 39  ? 86.954  128.042 155.905 1.00 32.93  ? 39  VAL B C   1 
ATOM   2990  O O   . VAL B 1 39  ? 86.503  127.231 155.088 1.00 32.93  ? 39  VAL B O   1 
ATOM   2991  C CB  . VAL B 1 39  ? 88.704  126.721 157.140 1.00 32.93  ? 39  VAL B CB  1 
ATOM   2992  C CG1 . VAL B 1 39  ? 89.641  127.325 156.115 1.00 32.93  ? 39  VAL B CG1 1 
ATOM   2993  C CG2 . VAL B 1 39  ? 89.393  126.600 158.481 1.00 32.93  ? 39  VAL B CG2 1 
ATOM   2994  N N   . THR B 1 40  ? 87.050  129.344 155.659 1.00 29.85  ? 40  THR B N   1 
ATOM   2995  C CA  . THR B 1 40  ? 86.719  129.940 154.372 1.00 29.85  ? 40  THR B CA  1 
ATOM   2996  C C   . THR B 1 40  ? 88.010  130.424 153.730 1.00 29.85  ? 40  THR B C   1 
ATOM   2997  O O   . THR B 1 40  ? 88.638  131.363 154.229 1.00 29.85  ? 40  THR B O   1 
ATOM   2998  C CB  . THR B 1 40  ? 85.737  131.098 154.540 1.00 29.85  ? 40  THR B CB  1 
ATOM   2999  O OG1 . THR B 1 40  ? 84.452  130.588 154.913 1.00 29.85  ? 40  THR B OG1 1 
ATOM   3000  C CG2 . THR B 1 40  ? 85.607  131.878 153.246 1.00 29.85  ? 40  THR B CG2 1 
ATOM   3001  N N   . CYS B 1 41  ? 88.405  129.790 152.630 1.00 28.26  ? 41  CYS B N   1 
ATOM   3002  C CA  . CYS B 1 41  ? 89.682  130.071 151.992 1.00 28.26  ? 41  CYS B CA  1 
ATOM   3003  C C   . CYS B 1 41  ? 89.472  130.584 150.576 1.00 28.26  ? 41  CYS B C   1 
ATOM   3004  O O   . CYS B 1 41  ? 88.635  130.065 149.834 1.00 28.26  ? 41  CYS B O   1 
ATOM   3005  C CB  . CYS B 1 41  ? 90.577  128.827 151.970 1.00 28.26  ? 41  CYS B CB  1 
ATOM   3006  S SG  . CYS B 1 41  ? 89.996  127.483 150.922 1.00 28.26  ? 41  CYS B SG  1 
ATOM   3007  N N   . ASN B 1 42  ? 90.229  131.617 150.217 1.00 33.08  ? 42  ASN B N   1 
ATOM   3008  C CA  . ASN B 1 42  ? 90.282  132.130 148.858 1.00 33.08  ? 42  ASN B CA  1 
ATOM   3009  C C   . ASN B 1 42  ? 91.739  132.330 148.472 1.00 33.08  ? 42  ASN B C   1 
ATOM   3010  O O   . ASN B 1 42  ? 92.579  132.656 149.313 1.00 33.08  ? 42  ASN B O   1 
ATOM   3011  C CB  . ASN B 1 42  ? 89.509  133.444 148.710 1.00 33.08  ? 42  ASN B CB  1 
ATOM   3012  C CG  . ASN B 1 42  ? 90.230  134.619 149.328 1.00 33.08  ? 42  ASN B CG  1 
ATOM   3013  O OD1 . ASN B 1 42  ? 90.806  134.511 150.409 1.00 33.08  ? 42  ASN B OD1 1 
ATOM   3014  N ND2 . ASN B 1 42  ? 90.204  135.754 148.642 1.00 33.08  ? 42  ASN B ND2 1 
ATOM   3015  N N   . ILE B 1 43  ? 92.036  132.130 147.193 1.00 37.10  ? 43  ILE B N   1 
ATOM   3016  C CA  . ILE B 1 43  ? 93.407  132.071 146.706 1.00 37.10  ? 43  ILE B CA  1 
ATOM   3017  C C   . ILE B 1 43  ? 93.587  133.111 145.612 1.00 37.10  ? 43  ILE B C   1 
ATOM   3018  O O   . ILE B 1 43  ? 92.798  133.165 144.664 1.00 37.10  ? 43  ILE B O   1 
ATOM   3019  C CB  . ILE B 1 43  ? 93.752  130.663 146.191 1.00 37.10  ? 43  ILE B CB  1 
ATOM   3020  C CG1 . ILE B 1 43  ? 94.907  130.715 145.199 1.00 37.10  ? 43  ILE B CG1 1 
ATOM   3021  C CG2 . ILE B 1 43  ? 92.543  130.028 145.549 1.00 37.10  ? 43  ILE B CG2 1 
ATOM   3022  C CD1 . ILE B 1 43  ? 95.156  129.398 144.512 1.00 37.10  ? 43  ILE B CD1 1 
ATOM   3023  N N   . PHE B 1 44  ? 94.625  133.932 145.746 1.00 37.76  ? 44  PHE B N   1 
ATOM   3024  C CA  . PHE B 1 44  ? 94.982  134.940 144.757 1.00 37.76  ? 44  PHE B CA  1 
ATOM   3025  C C   . PHE B 1 44  ? 96.198  134.443 143.990 1.00 37.76  ? 44  PHE B C   1 
ATOM   3026  O O   . PHE B 1 44  ? 97.243  134.176 144.591 1.00 37.76  ? 44  PHE B O   1 
ATOM   3027  C CB  . PHE B 1 44  ? 95.275  136.281 145.431 1.00 37.76  ? 44  PHE B CB  1 
ATOM   3028  C CG  . PHE B 1 44  ? 95.873  137.318 144.515 1.00 37.76  ? 44  PHE B CG  1 
ATOM   3029  C CD1 . PHE B 1 44  ? 97.240  137.382 144.308 1.00 37.76  ? 44  PHE B CD1 1 
ATOM   3030  C CD2 . PHE B 1 44  ? 95.067  138.245 143.882 1.00 37.76  ? 44  PHE B CD2 1 
ATOM   3031  C CE1 . PHE B 1 44  ? 97.786  138.336 143.474 1.00 37.76  ? 44  PHE B CE1 1 
ATOM   3032  C CE2 . PHE B 1 44  ? 95.611  139.204 143.049 1.00 37.76  ? 44  PHE B CE2 1 
ATOM   3033  C CZ  . PHE B 1 44  ? 96.971  139.248 142.846 1.00 37.76  ? 44  PHE B CZ  1 
ATOM   3034  N N   . ILE B 1 45  ? 96.068  134.333 142.676 1.00 32.26  ? 45  ILE B N   1 
ATOM   3035  C CA  . ILE B 1 45  ? 97.158  133.866 141.829 1.00 32.26  ? 45  ILE B CA  1 
ATOM   3036  C C   . ILE B 1 45  ? 98.023  135.055 141.444 1.00 32.26  ? 45  ILE B C   1 
ATOM   3037  O O   . ILE B 1 45  ? 97.517  136.072 140.958 1.00 32.26  ? 45  ILE B O   1 
ATOM   3038  C CB  . ILE B 1 45  ? 96.621  133.149 140.582 1.00 32.26  ? 45  ILE B CB  1 
ATOM   3039  C CG1 . ILE B 1 45  ? 96.078  131.773 140.956 1.00 32.26  ? 45  ILE B CG1 1 
ATOM   3040  C CG2 . ILE B 1 45  ? 97.710  133.018 139.540 1.00 32.26  ? 45  ILE B CG2 1 
ATOM   3041  C CD1 . ILE B 1 45  ? 95.846  130.876 139.771 1.00 32.26  ? 45  ILE B CD1 1 
ATOM   3042  N N   . ASN B 1 46  ? 99.329  134.932 141.664 1.00 33.87  ? 46  ASN B N   1 
ATOM   3043  C CA  . ASN B 1 46  ? 100.276 135.990 141.339 1.00 33.87  ? 46  ASN B CA  1 
ATOM   3044  C C   . ASN B 1 46  ? 100.986 135.745 140.016 1.00 33.87  ? 46  ASN B C   1 
ATOM   3045  O O   . ASN B 1 46  ? 101.023 136.630 139.158 1.00 33.87  ? 46  ASN B O   1 
ATOM   3046  C CB  . ASN B 1 46  ? 101.305 136.137 142.463 1.00 33.87  ? 46  ASN B CB  1 
ATOM   3047  C CG  . ASN B 1 46  ? 102.223 137.318 142.258 1.00 33.87  ? 46  ASN B CG  1 
ATOM   3048  O OD1 . ASN B 1 46  ? 101.876 138.275 141.570 1.00 33.87  ? 46  ASN B OD1 1 
ATOM   3049  N ND2 . ASN B 1 46  ? 103.405 137.260 142.856 1.00 33.87  ? 46  ASN B ND2 1 
ATOM   3050  N N   . SER B 1 47  ? 101.553 134.557 139.834 1.00 38.03  ? 47  SER B N   1 
ATOM   3051  C CA  . SER B 1 47  ? 102.251 134.204 138.610 1.00 38.03  ? 47  SER B CA  1 
ATOM   3052  C C   . SER B 1 47  ? 101.799 132.830 138.144 1.00 38.03  ? 47  SER B C   1 
ATOM   3053  O O   . SER B 1 47  ? 101.429 131.972 138.949 1.00 38.03  ? 47  SER B O   1 
ATOM   3054  C CB  . SER B 1 47  ? 103.769 134.212 138.801 1.00 38.03  ? 47  SER B CB  1 
ATOM   3055  O OG  . SER B 1 47  ? 104.419 133.587 137.709 1.00 38.03  ? 47  SER B OG  1 
ATOM   3056  N N   . PHE B 1 48  ? 101.839 132.631 136.832 1.00 34.76  ? 48  PHE B N   1 
ATOM   3057  C CA  . PHE B 1 48  ? 101.385 131.394 136.216 1.00 34.76  ? 48  PHE B CA  1 
ATOM   3058  C C   . PHE B 1 48  ? 102.228 131.163 134.975 1.00 34.76  ? 48  PHE B C   1 
ATOM   3059  O O   . PHE B 1 48  ? 102.353 132.064 134.141 1.00 34.76  ? 48  PHE B O   1 
ATOM   3060  C CB  . PHE B 1 48  ? 99.899  131.484 135.854 1.00 34.76  ? 48  PHE B CB  1 
ATOM   3061  C CG  . PHE B 1 48  ? 99.201  130.159 135.775 1.00 34.76  ? 48  PHE B CG  1 
ATOM   3062  C CD1 . PHE B 1 48  ? 99.675  129.153 134.954 1.00 34.76  ? 48  PHE B CD1 1 
ATOM   3063  C CD2 . PHE B 1 48  ? 98.051  129.930 136.506 1.00 34.76  ? 48  PHE B CD2 1 
ATOM   3064  C CE1 . PHE B 1 48  ? 99.025  127.941 134.877 1.00 34.76  ? 48  PHE B CE1 1 
ATOM   3065  C CE2 . PHE B 1 48  ? 97.398  128.721 136.431 1.00 34.76  ? 48  PHE B CE2 1 
ATOM   3066  C CZ  . PHE B 1 48  ? 97.885  127.725 135.616 1.00 34.76  ? 48  PHE B CZ  1 
ATOM   3067  N N   . GLY B 1 49  ? 102.807 129.975 134.851 1.00 32.59  ? 49  GLY B N   1 
ATOM   3068  C CA  . GLY B 1 49  ? 103.612 129.686 133.680 1.00 32.59  ? 49  GLY B CA  1 
ATOM   3069  C C   . GLY B 1 49  ? 104.427 128.424 133.866 1.00 32.59  ? 49  GLY B C   1 
ATOM   3070  O O   . GLY B 1 49  ? 104.161 127.622 134.762 1.00 32.59  ? 49  GLY B O   1 
ATOM   3071  N N   . SER B 1 50  ? 105.429 128.274 132.999 1.00 38.34  ? 50  SER B N   1 
ATOM   3072  C CA  . SER B 1 50  ? 106.284 127.088 132.965 1.00 38.34  ? 50  SER B CA  1 
ATOM   3073  C C   . SER B 1 50  ? 105.457 125.816 132.806 1.00 38.34  ? 50  SER B C   1 
ATOM   3074  O O   . SER B 1 50  ? 105.739 124.789 133.426 1.00 38.34  ? 50  SER B O   1 
ATOM   3075  C CB  . SER B 1 50  ? 107.173 127.005 134.206 1.00 38.34  ? 50  SER B CB  1 
ATOM   3076  O OG  . SER B 1 50  ? 107.857 125.765 134.254 1.00 38.34  ? 50  SER B OG  1 
ATOM   3077  N N   . ILE B 1 51  ? 104.429 125.882 131.963 1.00 40.70  ? 51  ILE B N   1 
ATOM   3078  C CA  . ILE B 1 51  ? 103.569 124.731 131.699 1.00 40.70  ? 51  ILE B CA  1 
ATOM   3079  C C   . ILE B 1 51  ? 104.345 123.795 130.778 1.00 40.70  ? 51  ILE B C   1 
ATOM   3080  O O   . ILE B 1 51  ? 104.395 123.998 129.565 1.00 40.70  ? 51  ILE B O   1 
ATOM   3081  C CB  . ILE B 1 51  ? 102.230 125.143 131.088 1.00 40.70  ? 51  ILE B CB  1 
ATOM   3082  C CG1 . ILE B 1 51  ? 101.531 126.166 131.982 1.00 40.70  ? 51  ILE B CG1 1 
ATOM   3083  C CG2 . ILE B 1 51  ? 101.347 123.925 130.876 1.00 40.70  ? 51  ILE B CG2 1 
ATOM   3084  C CD1 . ILE B 1 51  ? 100.247 126.697 131.403 1.00 40.70  ? 51  ILE B CD1 1 
ATOM   3085  N N   . ALA B 1 52  ? 104.953 122.766 131.355 1.00 47.71  ? 52  ALA B N   1 
ATOM   3086  C CA  . ALA B 1 52  ? 105.756 121.806 130.611 1.00 47.71  ? 52  ALA B CA  1 
ATOM   3087  C C   . ALA B 1 52  ? 104.997 120.490 130.533 1.00 47.71  ? 52  ALA B C   1 
ATOM   3088  O O   . ALA B 1 52  ? 104.704 119.876 131.564 1.00 47.71  ? 52  ALA B O   1 
ATOM   3089  C CB  . ALA B 1 52  ? 107.120 121.605 131.270 1.00 47.71  ? 52  ALA B CB  1 
ATOM   3090  N N   . GLU B 1 53  ? 104.682 120.062 129.313 1.00 55.85  ? 53  GLU B N   1 
ATOM   3091  C CA  . GLU B 1 53  ? 103.989 118.799 129.108 1.00 55.85  ? 53  GLU B CA  1 
ATOM   3092  C C   . GLU B 1 53  ? 104.928 117.602 129.109 1.00 55.85  ? 53  GLU B C   1 
ATOM   3093  O O   . GLU B 1 53  ? 104.451 116.465 129.180 1.00 55.85  ? 53  GLU B O   1 
ATOM   3094  C CB  . GLU B 1 53  ? 103.203 118.846 127.798 1.00 55.85  ? 53  GLU B CB  1 
ATOM   3095  C CG  . GLU B 1 53  ? 103.901 119.616 126.700 1.00 55.85  ? 53  GLU B CG  1 
ATOM   3096  C CD  . GLU B 1 53  ? 102.928 120.220 125.714 1.00 55.85  ? 53  GLU B CD  1 
ATOM   3097  O OE1 . GLU B 1 53  ? 101.709 120.012 125.881 1.00 55.85  ? 53  GLU B OE1 1 
ATOM   3098  O OE2 . GLU B 1 53  ? 103.382 120.908 124.777 1.00 55.85  ? 53  GLU B OE2 1 
ATOM   3099  N N   . THR B 1 54  ? 106.241 117.825 129.023 1.00 53.60  ? 54  THR B N   1 
ATOM   3100  C CA  . THR B 1 54  ? 107.180 116.716 129.135 1.00 53.60  ? 54  THR B CA  1 
ATOM   3101  C C   . THR B 1 54  ? 107.118 116.088 130.520 1.00 53.60  ? 54  THR B C   1 
ATOM   3102  O O   . THR B 1 54  ? 107.124 114.859 130.655 1.00 53.60  ? 54  THR B O   1 
ATOM   3103  C CB  . THR B 1 54  ? 108.599 117.192 128.831 1.00 53.60  ? 54  THR B CB  1 
ATOM   3104  O OG1 . THR B 1 54  ? 108.584 118.037 127.674 1.00 53.60  ? 54  THR B OG1 1 
ATOM   3105  C CG2 . THR B 1 54  ? 109.508 116.005 128.567 1.00 53.60  ? 54  THR B CG2 1 
ATOM   3106  N N   . THR B 1 55  ? 107.058 116.916 131.559 1.00 53.81  ? 55  THR B N   1 
ATOM   3107  C CA  . THR B 1 55  ? 106.929 116.446 132.930 1.00 53.81  ? 55  THR B CA  1 
ATOM   3108  C C   . THR B 1 55  ? 105.474 116.382 133.383 1.00 53.81  ? 55  THR B C   1 
ATOM   3109  O O   . THR B 1 55  ? 105.205 115.932 134.502 1.00 53.81  ? 55  THR B O   1 
ATOM   3110  C CB  . THR B 1 55  ? 107.741 117.349 133.866 1.00 53.81  ? 55  THR B CB  1 
ATOM   3111  O OG1 . THR B 1 55  ? 108.963 117.720 133.219 1.00 53.81  ? 55  THR B OG1 1 
ATOM   3112  C CG2 . THR B 1 55  ? 108.102 116.610 135.146 1.00 53.81  ? 55  THR B CG2 1 
ATOM   3113  N N   . MET B 1 56  ? 104.539 116.827 132.541 1.00 51.13  ? 56  MET B N   1 
ATOM   3114  C CA  . MET B 1 56  ? 103.102 116.685 132.788 1.00 51.13  ? 56  MET B CA  1 
ATOM   3115  C C   . MET B 1 56  ? 102.653 117.497 134.000 1.00 51.13  ? 56  MET B C   1 
ATOM   3116  O O   . MET B 1 56  ? 101.823 117.050 134.792 1.00 51.13  ? 56  MET B O   1 
ATOM   3117  C CB  . MET B 1 56  ? 102.717 115.213 132.954 1.00 51.13  ? 56  MET B CB  1 
ATOM   3118  C CG  . MET B 1 56  ? 102.365 114.499 131.663 1.00 51.13  ? 56  MET B CG  1 
ATOM   3119  S SD  . MET B 1 56  ? 100.888 115.151 130.871 1.00 51.13  ? 56  MET B SD  1 
ATOM   3120  C CE  . MET B 1 56  ? 100.312 113.700 129.994 1.00 51.13  ? 56  MET B CE  1 
ATOM   3121  N N   . ASP B 1 57  ? 103.194 118.704 134.148 1.00 42.48  ? 57  ASP B N   1 
ATOM   3122  C CA  . ASP B 1 57  ? 102.857 119.545 135.287 1.00 42.48  ? 57  ASP B CA  1 
ATOM   3123  C C   . ASP B 1 57  ? 102.985 121.010 134.892 1.00 42.48  ? 57  ASP B C   1 
ATOM   3124  O O   . ASP B 1 57  ? 103.245 121.345 133.734 1.00 42.48  ? 57  ASP B O   1 
ATOM   3125  C CB  . ASP B 1 57  ? 103.732 119.201 136.498 1.00 42.48  ? 57  ASP B CB  1 
ATOM   3126  C CG  . ASP B 1 57  ? 105.209 119.484 136.268 1.00 42.48  ? 57  ASP B CG  1 
ATOM   3127  O OD1 . ASP B 1 57  ? 105.569 120.604 135.848 1.00 42.48  ? 57  ASP B OD1 1 
ATOM   3128  O OD2 . ASP B 1 57  ? 106.023 118.574 136.522 1.00 42.48  ? 57  ASP B OD2 1 
ATOM   3129  N N   . TYR B 1 58  ? 102.802 121.886 135.877 1.00 32.35  ? 58  TYR B N   1 
ATOM   3130  C CA  . TYR B 1 58  ? 102.937 123.319 135.677 1.00 32.35  ? 58  TYR B CA  1 
ATOM   3131  C C   . TYR B 1 58  ? 103.237 123.972 137.016 1.00 32.35  ? 58  TYR B C   1 
ATOM   3132  O O   . TYR B 1 58  ? 102.993 123.394 138.077 1.00 32.35  ? 58  TYR B O   1 
ATOM   3133  C CB  . TYR B 1 58  ? 101.677 123.924 135.053 1.00 32.35  ? 58  TYR B CB  1 
ATOM   3134  C CG  . TYR B 1 58  ? 100.463 123.868 135.947 1.00 32.35  ? 58  TYR B CG  1 
ATOM   3135  C CD1 . TYR B 1 58  ? 99.709  122.713 136.051 1.00 32.35  ? 58  TYR B CD1 1 
ATOM   3136  C CD2 . TYR B 1 58  ? 100.064 124.975 136.677 1.00 32.35  ? 58  TYR B CD2 1 
ATOM   3137  C CE1 . TYR B 1 58  ? 98.597  122.658 136.862 1.00 32.35  ? 58  TYR B CE1 1 
ATOM   3138  C CE2 . TYR B 1 58  ? 98.951  124.929 137.492 1.00 32.35  ? 58  TYR B CE2 1 
ATOM   3139  C CZ  . TYR B 1 58  ? 98.223  123.768 137.579 1.00 32.35  ? 58  TYR B CZ  1 
ATOM   3140  O OH  . TYR B 1 58  ? 97.114  123.715 138.387 1.00 32.35  ? 58  TYR B OH  1 
ATOM   3141  N N   . ARG B 1 59  ? 103.768 125.188 136.958 1.00 31.53  ? 59  ARG B N   1 
ATOM   3142  C CA  . ARG B 1 59  ? 104.152 125.934 138.147 1.00 31.53  ? 59  ARG B CA  1 
ATOM   3143  C C   . ARG B 1 59  ? 103.177 127.078 138.378 1.00 31.53  ? 59  ARG B C   1 
ATOM   3144  O O   . ARG B 1 59  ? 102.760 127.753 137.433 1.00 31.53  ? 59  ARG B O   1 
ATOM   3145  C CB  . ARG B 1 59  ? 105.578 126.478 138.021 1.00 31.53  ? 59  ARG B CB  1 
ATOM   3146  C CG  . ARG B 1 59  ? 105.767 127.885 138.565 1.00 31.53  ? 59  ARG B CG  1 
ATOM   3147  C CD  . ARG B 1 59  ? 107.235 128.237 138.712 1.00 31.53  ? 59  ARG B CD  1 
ATOM   3148  N NE  . ARG B 1 59  ? 107.785 127.750 139.971 1.00 31.53  ? 59  ARG B NE  1 
ATOM   3149  C CZ  . ARG B 1 59  ? 108.444 126.608 140.108 1.00 31.53  ? 59  ARG B CZ  1 
ATOM   3150  N NH1 . ARG B 1 59  ? 108.660 125.807 139.078 1.00 31.53  ? 59  ARG B NH1 1 
ATOM   3151  N NH2 . ARG B 1 59  ? 108.897 126.261 141.309 1.00 31.53  ? 59  ARG B NH2 1 
ATOM   3152  N N   . VAL B 1 60  ? 102.811 127.286 139.641 1.00 33.12  ? 60  VAL B N   1 
ATOM   3153  C CA  . VAL B 1 60  ? 101.911 128.359 140.034 1.00 33.12  ? 60  VAL B CA  1 
ATOM   3154  C C   . VAL B 1 60  ? 102.521 129.084 141.226 1.00 33.12  ? 60  VAL B C   1 
ATOM   3155  O O   . VAL B 1 60  ? 103.380 128.554 141.933 1.00 33.12  ? 60  VAL B O   1 
ATOM   3156  C CB  . VAL B 1 60  ? 100.499 127.834 140.368 1.00 33.12  ? 60  VAL B CB  1 
ATOM   3157  C CG1 . VAL B 1 60  ? 100.436 127.346 141.798 1.00 33.12  ? 60  VAL B CG1 1 
ATOM   3158  C CG2 . VAL B 1 60  ? 99.456  128.903 140.122 1.00 33.12  ? 60  VAL B CG2 1 
ATOM   3159  N N   . ASN B 1 61  ? 102.079 130.322 141.432 1.00 47.29  ? 61  ASN B N   1 
ATOM   3160  C CA  . ASN B 1 61  ? 102.540 131.150 142.543 1.00 47.29  ? 61  ASN B CA  1 
ATOM   3161  C C   . ASN B 1 61  ? 101.320 131.855 143.114 1.00 47.29  ? 61  ASN B C   1 
ATOM   3162  O O   . ASN B 1 61  ? 100.758 132.741 142.466 1.00 47.29  ? 61  ASN B O   1 
ATOM   3163  C CB  . ASN B 1 61  ? 103.595 132.153 142.079 1.00 47.29  ? 61  ASN B CB  1 
ATOM   3164  C CG  . ASN B 1 61  ? 104.260 132.882 143.227 1.00 47.29  ? 61  ASN B CG  1 
ATOM   3165  O OD1 . ASN B 1 61  ? 103.645 133.134 144.260 1.00 47.29  ? 61  ASN B OD1 1 
ATOM   3166  N ND2 . ASN B 1 61  ? 105.526 133.231 143.047 1.00 47.29  ? 61  ASN B ND2 1 
ATOM   3167  N N   . ILE B 1 62  ? 100.913 131.475 144.321 1.00 47.29  ? 62  ILE B N   1 
ATOM   3168  C CA  . ILE B 1 62  ? 99.614  131.873 144.845 1.00 47.29  ? 62  ILE B CA  1 
ATOM   3169  C C   . ILE B 1 62  ? 99.778  132.575 146.183 1.00 47.29  ? 62  ILE B C   1 
ATOM   3170  O O   . ILE B 1 62  ? 100.749 132.357 146.913 1.00 47.29  ? 62  ILE B O   1 
ATOM   3171  C CB  . ILE B 1 62  ? 98.677  130.658 144.990 1.00 47.29  ? 62  ILE B CB  1 
ATOM   3172  C CG1 . ILE B 1 62  ? 99.136  129.772 146.142 1.00 47.29  ? 62  ILE B CG1 1 
ATOM   3173  C CG2 . ILE B 1 62  ? 98.650  129.857 143.711 1.00 47.29  ? 62  ILE B CG2 1 
ATOM   3174  C CD1 . ILE B 1 62  ? 98.275  128.556 146.345 1.00 47.29  ? 62  ILE B CD1 1 
ATOM   3175  N N   . PHE B 1 63  ? 98.814  133.442 146.492 1.00 47.29  ? 63  PHE B N   1 
ATOM   3176  C CA  . PHE B 1 63  ? 98.694  134.064 147.808 1.00 47.29  ? 63  PHE B CA  1 
ATOM   3177  C C   . PHE B 1 63  ? 97.550  133.368 148.539 1.00 47.29  ? 63  PHE B C   1 
ATOM   3178  O O   . PHE B 1 63  ? 96.421  133.851 148.579 1.00 47.29  ? 63  PHE B O   1 
ATOM   3179  C CB  . PHE B 1 63  ? 98.429  135.561 147.684 1.00 47.29  ? 63  PHE B CB  1 
ATOM   3180  C CG  . PHE B 1 63  ? 99.632  136.379 147.328 1.00 47.29  ? 63  PHE B CG  1 
ATOM   3181  C CD1 . PHE B 1 63  ? 100.515 135.963 146.354 1.00 47.29  ? 63  PHE B CD1 1 
ATOM   3182  C CD2 . PHE B 1 63  ? 99.864  137.583 147.959 1.00 47.29  ? 63  PHE B CD2 1 
ATOM   3183  C CE1 . PHE B 1 63  ? 101.611 136.728 146.026 1.00 47.29  ? 63  PHE B CE1 1 
ATOM   3184  C CE2 . PHE B 1 63  ? 100.956 138.349 147.637 1.00 47.29  ? 63  PHE B CE2 1 
ATOM   3185  C CZ  . PHE B 1 63  ? 101.832 137.921 146.669 1.00 47.29  ? 63  PHE B CZ  1 
ATOM   3186  N N   . LEU B 1 64  ? 97.850  132.217 149.129 1.00 47.29  ? 64  LEU B N   1 
ATOM   3187  C CA  . LEU B 1 64  ? 96.808  131.443 149.790 1.00 47.29  ? 64  LEU B CA  1 
ATOM   3188  C C   . LEU B 1 64  ? 96.332  132.162 151.046 1.00 47.29  ? 64  LEU B C   1 
ATOM   3189  O O   . LEU B 1 64  ? 97.143  132.576 151.877 1.00 47.29  ? 64  LEU B O   1 
ATOM   3190  C CB  . LEU B 1 64  ? 97.322  130.052 150.138 1.00 47.29  ? 64  LEU B CB  1 
ATOM   3191  C CG  . LEU B 1 64  ? 96.367  129.212 150.978 1.00 47.29  ? 64  LEU B CG  1 
ATOM   3192  C CD1 . LEU B 1 64  ? 95.050  129.044 150.252 1.00 47.29  ? 64  LEU B CD1 1 
ATOM   3193  C CD2 . LEU B 1 64  ? 96.987  127.867 151.283 1.00 47.29  ? 64  LEU B CD2 1 
ATOM   3194  N N   . ARG B 1 65  ? 95.016  132.308 151.184 1.00 44.11  ? 65  ARG B N   1 
ATOM   3195  C CA  . ARG B 1 65  ? 94.415  133.016 152.308 1.00 44.11  ? 65  ARG B CA  1 
ATOM   3196  C C   . ARG B 1 65  ? 93.363  132.132 152.954 1.00 44.11  ? 65  ARG B C   1 
ATOM   3197  O O   . ARG B 1 65  ? 92.536  131.540 152.255 1.00 44.11  ? 65  ARG B O   1 
ATOM   3198  C CB  . ARG B 1 65  ? 93.784  134.334 151.857 1.00 44.11  ? 65  ARG B CB  1 
ATOM   3199  C CG  . ARG B 1 65  ? 94.669  135.154 150.943 1.00 44.11  ? 65  ARG B CG  1 
ATOM   3200  C CD  . ARG B 1 65  ? 94.216  136.594 150.879 1.00 44.11  ? 65  ARG B CD  1 
ATOM   3201  N NE  . ARG B 1 65  ? 95.099  137.395 150.041 1.00 44.11  ? 65  ARG B NE  1 
ATOM   3202  C CZ  . ARG B 1 65  ? 94.790  137.819 148.824 1.00 44.11  ? 65  ARG B CZ  1 
ATOM   3203  N NH1 . ARG B 1 65  ? 93.622  137.538 148.271 1.00 44.11  ? 65  ARG B NH1 1 
ATOM   3204  N NH2 . ARG B 1 65  ? 95.673  138.545 148.147 1.00 44.11  ? 65  ARG B NH2 1 
ATOM   3205  N N   . GLN B 1 66  ? 93.390  132.044 154.281 1.00 47.29  ? 66  GLN B N   1 
ATOM   3206  C CA  . GLN B 1 66  ? 92.440  131.237 155.033 1.00 47.29  ? 66  GLN B CA  1 
ATOM   3207  C C   . GLN B 1 66  ? 91.858  132.059 156.171 1.00 47.29  ? 66  GLN B C   1 
ATOM   3208  O O   . GLN B 1 66  ? 92.570  132.838 156.808 1.00 47.29  ? 66  GLN B O   1 
ATOM   3209  C CB  . GLN B 1 66  ? 93.097  129.976 155.598 1.00 47.29  ? 66  GLN B CB  1 
ATOM   3210  C CG  . GLN B 1 66  ? 94.016  129.264 154.629 1.00 47.29  ? 66  GLN B CG  1 
ATOM   3211  C CD  . GLN B 1 66  ? 94.730  128.098 155.267 1.00 47.29  ? 66  GLN B CD  1 
ATOM   3212  O OE1 . GLN B 1 66  ? 94.123  127.298 155.974 1.00 47.29  ? 66  GLN B OE1 1 
ATOM   3213  N NE2 . GLN B 1 66  ? 96.029  127.994 155.022 1.00 47.29  ? 66  GLN B NE2 1 
ATOM   3214  N N   . LYS B 1 67  ? 90.565  131.881 156.424 1.00 35.92  ? 67  LYS B N   1 
ATOM   3215  C CA  . LYS B 1 67  ? 89.885  132.548 157.525 1.00 35.92  ? 67  LYS B CA  1 
ATOM   3216  C C   . LYS B 1 67  ? 89.086  131.529 158.320 1.00 35.92  ? 67  LYS B C   1 
ATOM   3217  O O   . LYS B 1 67  ? 88.464  130.633 157.745 1.00 35.92  ? 67  LYS B O   1 
ATOM   3218  C CB  . LYS B 1 67  ? 88.952  133.655 157.027 1.00 35.92  ? 67  LYS B CB  1 
ATOM   3219  C CG  . LYS B 1 67  ? 89.519  134.500 155.902 1.00 35.92  ? 67  LYS B CG  1 
ATOM   3220  C CD  . LYS B 1 67  ? 88.460  135.415 155.312 1.00 35.92  ? 67  LYS B CD  1 
ATOM   3221  C CE  . LYS B 1 67  ? 88.908  135.982 153.976 1.00 35.92  ? 67  LYS B CE  1 
ATOM   3222  N NZ  . LYS B 1 67  ? 87.857  136.825 153.346 1.00 35.92  ? 67  LYS B NZ  1 
ATOM   3223  N N   . TRP B 1 68  ? 89.101  131.671 159.642 1.00 33.65  ? 68  TRP B N   1 
ATOM   3224  C CA  . TRP B 1 68  ? 88.327  130.802 160.517 1.00 33.65  ? 68  TRP B CA  1 
ATOM   3225  C C   . TRP B 1 68  ? 87.999  131.567 161.791 1.00 33.65  ? 68  TRP B C   1 
ATOM   3226  O O   . TRP B 1 68  ? 88.291  132.759 161.916 1.00 33.65  ? 68  TRP B O   1 
ATOM   3227  C CB  . TRP B 1 68  ? 89.077  129.500 160.812 1.00 33.65  ? 68  TRP B CB  1 
ATOM   3228  C CG  . TRP B 1 68  ? 90.321  129.678 161.608 1.00 33.65  ? 68  TRP B CG  1 
ATOM   3229  C CD1 . TRP B 1 68  ? 90.436  129.637 162.963 1.00 33.65  ? 68  TRP B CD1 1 
ATOM   3230  C CD2 . TRP B 1 68  ? 91.636  129.918 161.101 1.00 33.65  ? 68  TRP B CD2 1 
ATOM   3231  N NE1 . TRP B 1 68  ? 91.741  129.840 163.334 1.00 33.65  ? 68  TRP B NE1 1 
ATOM   3232  C CE2 . TRP B 1 68  ? 92.498  130.016 162.207 1.00 33.65  ? 68  TRP B CE2 1 
ATOM   3233  C CE3 . TRP B 1 68  ? 92.168  130.061 159.819 1.00 33.65  ? 68  TRP B CE3 1 
ATOM   3234  C CZ2 . TRP B 1 68  ? 93.860  130.251 162.071 1.00 33.65  ? 68  TRP B CZ2 1 
ATOM   3235  C CZ3 . TRP B 1 68  ? 93.521  130.295 159.687 1.00 33.65  ? 68  TRP B CZ3 1 
ATOM   3236  C CH2 . TRP B 1 68  ? 94.351  130.388 160.805 1.00 33.65  ? 68  TRP B CH2 1 
ATOM   3237  N N   . ASN B 1 69  ? 87.382  130.873 162.743 1.00 36.51  ? 69  ASN B N   1 
ATOM   3238  C CA  . ASN B 1 69  ? 86.910  131.481 163.979 1.00 36.51  ? 69  ASN B CA  1 
ATOM   3239  C C   . ASN B 1 69  ? 87.570  130.808 165.172 1.00 36.51  ? 69  ASN B C   1 
ATOM   3240  O O   . ASN B 1 69  ? 87.565  129.577 165.277 1.00 36.51  ? 69  ASN B O   1 
ATOM   3241  C CB  . ASN B 1 69  ? 85.387  131.378 164.090 1.00 36.51  ? 69  ASN B CB  1 
ATOM   3242  C CG  . ASN B 1 69  ? 84.810  132.329 165.119 1.00 36.51  ? 69  ASN B CG  1 
ATOM   3243  O OD1 . ASN B 1 69  ? 85.460  132.667 166.108 1.00 36.51  ? 69  ASN B OD1 1 
ATOM   3244  N ND2 . ASN B 1 69  ? 83.578  132.768 164.890 1.00 36.51  ? 69  ASN B ND2 1 
ATOM   3245  N N   . ASP B 1 70  ? 88.132  131.614 166.064 1.00 39.97  ? 70  ASP B N   1 
ATOM   3246  C CA  . ASP B 1 70  ? 88.710  131.126 167.317 1.00 39.97  ? 70  ASP B CA  1 
ATOM   3247  C C   . ASP B 1 70  ? 88.047  131.837 168.485 1.00 39.97  ? 70  ASP B C   1 
ATOM   3248  O O   . ASP B 1 70  ? 88.330  133.027 168.720 1.00 39.97  ? 70  ASP B O   1 
ATOM   3249  C CB  . ASP B 1 70  ? 90.220  131.354 167.349 1.00 39.97  ? 70  ASP B CB  1 
ATOM   3250  C CG  . ASP B 1 70  ? 90.984  130.279 166.617 1.00 39.97  ? 70  ASP B CG  1 
ATOM   3251  O OD1 . ASP B 1 70  ? 90.339  129.358 166.079 1.00 39.97  ? 70  ASP B OD1 1 
ATOM   3252  O OD2 . ASP B 1 70  ? 92.229  130.351 166.584 1.00 39.97  ? 70  ASP B OD2 1 
ATOM   3253  N N   . PRO B 1 71  ? 87.171  131.176 169.242 1.00 41.89  ? 71  PRO B N   1 
ATOM   3254  C CA  . PRO B 1 71  ? 86.537  131.852 170.383 1.00 41.89  ? 71  PRO B CA  1 
ATOM   3255  C C   . PRO B 1 71  ? 87.520  132.284 171.455 1.00 41.89  ? 71  PRO B C   1 
ATOM   3256  O O   . PRO B 1 71  ? 87.200  133.188 172.236 1.00 41.89  ? 71  PRO B O   1 
ATOM   3257  C CB  . PRO B 1 71  ? 85.555  130.800 170.913 1.00 41.89  ? 71  PRO B CB  1 
ATOM   3258  C CG  . PRO B 1 71  ? 86.096  129.499 170.433 1.00 41.89  ? 71  PRO B CG  1 
ATOM   3259  C CD  . PRO B 1 71  ? 86.719  129.783 169.102 1.00 41.89  ? 71  PRO B CD  1 
ATOM   3260  N N   . ARG B 1 72  ? 88.703  131.676 171.519 1.00 40.50  ? 72  ARG B N   1 
ATOM   3261  C CA  . ARG B 1 72  ? 89.686  132.036 172.531 1.00 40.50  ? 72  ARG B CA  1 
ATOM   3262  C C   . ARG B 1 72  ? 90.486  133.280 172.172 1.00 40.50  ? 72  ARG B C   1 
ATOM   3263  O O   . ARG B 1 72  ? 91.201  133.802 173.034 1.00 40.50  ? 72  ARG B O   1 
ATOM   3264  C CB  . ARG B 1 72  ? 90.646  130.870 172.773 1.00 40.50  ? 72  ARG B CB  1 
ATOM   3265  C CG  . ARG B 1 72  ? 89.981  129.620 173.317 1.00 40.50  ? 72  ARG B CG  1 
ATOM   3266  C CD  . ARG B 1 72  ? 90.852  128.398 173.098 1.00 40.50  ? 72  ARG B CD  1 
ATOM   3267  N NE  . ARG B 1 72  ? 91.242  128.257 171.702 1.00 40.50  ? 72  ARG B NE  1 
ATOM   3268  C CZ  . ARG B 1 72  ? 91.903  127.219 171.210 1.00 40.50  ? 72  ARG B CZ  1 
ATOM   3269  N NH1 . ARG B 1 72  ? 92.270  126.208 171.979 1.00 40.50  ? 72  ARG B NH1 1 
ATOM   3270  N NH2 . ARG B 1 72  ? 92.202  127.195 169.915 1.00 40.50  ? 72  ARG B NH2 1 
ATOM   3271  N N   . LEU B 1 73  ? 90.389  133.766 170.937 1.00 39.77  ? 73  LEU B N   1 
ATOM   3272  C CA  . LEU B 1 73  ? 91.152  134.924 170.495 1.00 39.77  ? 73  LEU B CA  1 
ATOM   3273  C C   . LEU B 1 73  ? 90.343  136.213 170.528 1.00 39.77  ? 73  LEU B C   1 
ATOM   3274  O O   . LEU B 1 73  ? 90.814  137.239 170.028 1.00 39.77  ? 73  LEU B O   1 
ATOM   3275  C CB  . LEU B 1 73  ? 91.704  134.689 169.089 1.00 39.77  ? 73  LEU B CB  1 
ATOM   3276  C CG  . LEU B 1 73  ? 93.176  134.282 169.016 1.00 39.77  ? 73  LEU B CG  1 
ATOM   3277  C CD1 . LEU B 1 73  ? 93.386  132.930 169.668 1.00 39.77  ? 73  LEU B CD1 1 
ATOM   3278  C CD2 . LEU B 1 73  ? 93.654  134.262 167.579 1.00 39.77  ? 73  LEU B CD2 1 
ATOM   3279  N N   . ALA B 1 74  ? 89.141  136.187 171.095 1.00 46.42  ? 74  ALA B N   1 
ATOM   3280  C CA  . ALA B 1 74  ? 88.361  137.407 171.235 1.00 46.42  ? 74  ALA B CA  1 
ATOM   3281  C C   . ALA B 1 74  ? 89.018  138.326 172.255 1.00 46.42  ? 74  ALA B C   1 
ATOM   3282  O O   . ALA B 1 74  ? 89.359  137.898 173.361 1.00 46.42  ? 74  ALA B O   1 
ATOM   3283  C CB  . ALA B 1 74  ? 86.931  137.080 171.658 1.00 46.42  ? 74  ALA B CB  1 
ATOM   3284  N N   . TYR B 1 75  ? 89.191  139.591 171.887 1.00 60.26  ? 75  TYR B N   1 
ATOM   3285  C CA  . TYR B 1 75  ? 89.869  140.558 172.734 1.00 60.26  ? 75  TYR B CA  1 
ATOM   3286  C C   . TYR B 1 75  ? 89.016  141.810 172.877 1.00 60.26  ? 75  TYR B C   1 
ATOM   3287  O O   . TYR B 1 75  ? 88.189  142.120 172.015 1.00 60.26  ? 75  TYR B O   1 
ATOM   3288  C CB  . TYR B 1 75  ? 91.249  140.924 172.173 1.00 60.26  ? 75  TYR B CB  1 
ATOM   3289  C CG  . TYR B 1 75  ? 91.203  141.700 170.878 1.00 60.26  ? 75  TYR B CG  1 
ATOM   3290  C CD1 . TYR B 1 75  ? 90.989  141.058 169.668 1.00 60.26  ? 75  TYR B CD1 1 
ATOM   3291  C CD2 . TYR B 1 75  ? 91.377  143.075 170.866 1.00 60.26  ? 75  TYR B CD2 1 
ATOM   3292  C CE1 . TYR B 1 75  ? 90.948  141.764 168.485 1.00 60.26  ? 75  TYR B CE1 1 
ATOM   3293  C CE2 . TYR B 1 75  ? 91.337  143.789 169.688 1.00 60.26  ? 75  TYR B CE2 1 
ATOM   3294  C CZ  . TYR B 1 75  ? 91.122  143.129 168.501 1.00 60.26  ? 75  TYR B CZ  1 
ATOM   3295  O OH  . TYR B 1 75  ? 91.083  143.841 167.326 1.00 60.26  ? 75  TYR B OH  1 
ATOM   3296  N N   . SER B 1 76  ? 89.228  142.528 173.981 1.00 75.49  ? 76  SER B N   1 
ATOM   3297  C CA  . SER B 1 76  ? 88.472  143.737 174.269 1.00 75.49  ? 76  SER B CA  1 
ATOM   3298  C C   . SER B 1 76  ? 89.327  144.914 174.713 1.00 75.49  ? 76  SER B C   1 
ATOM   3299  O O   . SER B 1 76  ? 88.791  146.020 174.838 1.00 75.49  ? 76  SER B O   1 
ATOM   3300  C CB  . SER B 1 76  ? 87.415  143.464 175.351 1.00 75.49  ? 76  SER B CB  1 
ATOM   3301  O OG  . SER B 1 76  ? 86.643  142.319 175.034 1.00 75.49  ? 76  SER B OG  1 
ATOM   3302  N N   . GLU B 1 77  ? 90.624  144.718 174.964 1.00 88.80  ? 77  GLU B N   1 
ATOM   3303  C CA  . GLU B 1 77  ? 91.462  145.823 175.419 1.00 88.80  ? 77  GLU B CA  1 
ATOM   3304  C C   . GLU B 1 77  ? 91.587  146.903 174.351 1.00 88.80  ? 77  GLU B C   1 
ATOM   3305  O O   . GLU B 1 77  ? 91.509  148.099 174.655 1.00 88.80  ? 77  GLU B O   1 
ATOM   3306  C CB  . GLU B 1 77  ? 92.842  145.303 175.824 1.00 88.80  ? 77  GLU B CB  1 
ATOM   3307  C CG  . GLU B 1 77  ? 93.902  146.388 175.951 1.00 88.80  ? 77  GLU B CG  1 
ATOM   3308  C CD  . GLU B 1 77  ? 94.933  146.080 177.020 1.00 88.80  ? 77  GLU B CD  1 
ATOM   3309  O OE1 . GLU B 1 77  ? 94.762  145.077 177.744 1.00 88.80  ? 77  GLU B OE1 1 
ATOM   3310  O OE2 . GLU B 1 77  ? 95.916  146.842 177.137 1.00 88.80  ? 77  GLU B OE2 1 
ATOM   3311  N N   . TYR B 1 78  ? 91.776  146.504 173.094 1.00 81.41  ? 78  TYR B N   1 
ATOM   3312  C CA  . TYR B 1 78  ? 91.918  147.459 172.006 1.00 81.41  ? 78  TYR B CA  1 
ATOM   3313  C C   . TYR B 1 78  ? 90.592  147.612 171.284 1.00 81.41  ? 78  TYR B C   1 
ATOM   3314  O O   . TYR B 1 78  ? 90.093  146.629 170.714 1.00 81.41  ? 78  TYR B O   1 
ATOM   3315  C CB  . TYR B 1 78  ? 92.998  147.007 171.033 1.00 81.41  ? 78  TYR B CB  1 
ATOM   3316  C CG  . TYR B 1 78  ? 94.400  147.309 171.503 1.00 81.41  ? 78  TYR B CG  1 
ATOM   3317  C CD1 . TYR B 1 78  ? 94.620  148.060 172.648 1.00 81.41  ? 78  TYR B CD1 1 
ATOM   3318  C CD2 . TYR B 1 78  ? 95.503  146.847 170.801 1.00 81.41  ? 78  TYR B CD2 1 
ATOM   3319  C CE1 . TYR B 1 78  ? 95.898  148.340 173.083 1.00 81.41  ? 78  TYR B CE1 1 
ATOM   3320  C CE2 . TYR B 1 78  ? 96.786  147.122 171.228 1.00 81.41  ? 78  TYR B CE2 1 
ATOM   3321  C CZ  . TYR B 1 78  ? 96.977  147.869 172.369 1.00 81.41  ? 78  TYR B CZ  1 
ATOM   3322  O OH  . TYR B 1 78  ? 98.253  148.147 172.800 1.00 81.41  ? 78  TYR B OH  1 
ATOM   3323  N N   . PRO B 1 79  ? 89.984  148.801 171.282 1.00 82.65  ? 79  PRO B N   1 
ATOM   3324  C CA  . PRO B 1 79  ? 88.702  148.970 170.579 1.00 82.65  ? 79  PRO B CA  1 
ATOM   3325  C C   . PRO B 1 79  ? 88.788  148.736 169.080 1.00 82.65  ? 79  PRO B C   1 
ATOM   3326  O O   . PRO B 1 79  ? 87.763  148.428 168.459 1.00 82.65  ? 79  PRO B O   1 
ATOM   3327  C CB  . PRO B 1 79  ? 88.314  150.420 170.898 1.00 82.65  ? 79  PRO B CB  1 
ATOM   3328  C CG  . PRO B 1 79  ? 89.601  151.092 171.246 1.00 82.65  ? 79  PRO B CG  1 
ATOM   3329  C CD  . PRO B 1 79  ? 90.438  150.048 171.919 1.00 82.65  ? 79  PRO B CD  1 
ATOM   3330  N N   . ASP B 1 80  ? 89.966  148.877 168.479 1.00 71.55  ? 80  ASP B N   1 
ATOM   3331  C CA  . ASP B 1 80  ? 90.110  148.627 167.052 1.00 71.55  ? 80  ASP B CA  1 
ATOM   3332  C C   . ASP B 1 80  ? 89.939  147.143 166.753 1.00 71.55  ? 80  ASP B C   1 
ATOM   3333  O O   . ASP B 1 80  ? 90.439  146.283 167.484 1.00 71.55  ? 80  ASP B O   1 
ATOM   3334  C CB  . ASP B 1 80  ? 91.475  149.109 166.565 1.00 71.55  ? 80  ASP B CB  1 
ATOM   3335  C CG  . ASP B 1 80  ? 91.533  149.268 165.060 1.00 71.55  ? 80  ASP B CG  1 
ATOM   3336  O OD1 . ASP B 1 80  ? 90.474  149.153 164.407 1.00 71.55  ? 80  ASP B OD1 1 
ATOM   3337  O OD2 . ASP B 1 80  ? 92.637  149.508 164.528 1.00 71.55  ? 80  ASP B OD2 1 
ATOM   3338  N N   . ASP B 1 81  ? 89.227  146.843 165.667 1.00 62.06  ? 81  ASP B N   1 
ATOM   3339  C CA  . ASP B 1 81  ? 88.950  145.459 165.295 1.00 62.06  ? 81  ASP B CA  1 
ATOM   3340  C C   . ASP B 1 81  ? 90.062  144.874 164.426 1.00 62.06  ? 81  ASP B C   1 
ATOM   3341  O O   . ASP B 1 81  ? 90.679  143.869 164.791 1.00 62.06  ? 81  ASP B O   1 
ATOM   3342  C CB  . ASP B 1 81  ? 87.598  145.369 164.579 1.00 62.06  ? 81  ASP B CB  1 
ATOM   3343  C CG  . ASP B 1 81  ? 87.413  146.457 163.543 1.00 62.06  ? 81  ASP B CG  1 
ATOM   3344  O OD1 . ASP B 1 81  ? 88.346  147.266 163.360 1.00 62.06  ? 81  ASP B OD1 1 
ATOM   3345  O OD2 . ASP B 1 81  ? 86.338  146.502 162.911 1.00 62.06  ? 81  ASP B OD2 1 
ATOM   3346  N N   . SER B 1 82  ? 90.331  145.494 163.281 1.00 54.09  ? 82  SER B N   1 
ATOM   3347  C CA  . SER B 1 82  ? 91.372  145.011 162.380 1.00 54.09  ? 82  SER B CA  1 
ATOM   3348  C C   . SER B 1 82  ? 92.736  145.297 162.992 1.00 54.09  ? 82  SER B C   1 
ATOM   3349  O O   . SER B 1 82  ? 93.178  146.450 163.032 1.00 54.09  ? 82  SER B O   1 
ATOM   3350  C CB  . SER B 1 82  ? 91.234  145.672 161.013 1.00 54.09  ? 82  SER B CB  1 
ATOM   3351  O OG  . SER B 1 82  ? 89.887  145.656 160.573 1.00 54.09  ? 82  SER B OG  1 
ATOM   3352  N N   . LEU B 1 83  ? 93.409  144.252 163.467 1.00 43.39  ? 83  LEU B N   1 
ATOM   3353  C CA  . LEU B 1 83  ? 94.666  144.389 164.201 1.00 43.39  ? 83  LEU B CA  1 
ATOM   3354  C C   . LEU B 1 83  ? 95.723  143.498 163.556 1.00 43.39  ? 83  LEU B C   1 
ATOM   3355  O O   . LEU B 1 83  ? 95.760  142.291 163.809 1.00 43.39  ? 83  LEU B O   1 
ATOM   3356  C CB  . LEU B 1 83  ? 94.473  144.034 165.671 1.00 43.39  ? 83  LEU B CB  1 
ATOM   3357  C CG  . LEU B 1 83  ? 95.693  144.197 166.575 1.00 43.39  ? 83  LEU B CG  1 
ATOM   3358  C CD1 . LEU B 1 83  ? 95.982  145.668 166.820 1.00 43.39  ? 83  LEU B CD1 1 
ATOM   3359  C CD2 . LEU B 1 83  ? 95.479  143.466 167.886 1.00 43.39  ? 83  LEU B CD2 1 
ATOM   3360  N N   . ASP B 1 84  ? 96.578  144.090 162.728 1.00 44.30  ? 84  ASP B N   1 
ATOM   3361  C CA  . ASP B 1 84  ? 97.713  143.360 162.181 1.00 44.30  ? 84  ASP B CA  1 
ATOM   3362  C C   . ASP B 1 84  ? 98.700  143.022 163.290 1.00 44.30  ? 84  ASP B C   1 
ATOM   3363  O O   . ASP B 1 84  ? 98.944  143.826 164.193 1.00 44.30  ? 84  ASP B O   1 
ATOM   3364  C CB  . ASP B 1 84  ? 98.410  144.182 161.099 1.00 44.30  ? 84  ASP B CB  1 
ATOM   3365  C CG  . ASP B 1 84  ? 97.554  144.367 159.864 1.00 44.30  ? 84  ASP B CG  1 
ATOM   3366  O OD1 . ASP B 1 84  ? 96.956  143.376 159.397 1.00 44.30  ? 84  ASP B OD1 1 
ATOM   3367  O OD2 . ASP B 1 84  ? 97.480  145.506 159.359 1.00 44.30  ? 84  ASP B OD2 1 
ATOM   3368  N N   . LEU B 1 85  ? 99.272  141.825 163.218 1.00 40.54  ? 85  LEU B N   1 
ATOM   3369  C CA  . LEU B 1 85  ? 100.236 141.368 164.205 1.00 40.54  ? 85  LEU B CA  1 
ATOM   3370  C C   . LEU B 1 85  ? 101.485 140.866 163.500 1.00 40.54  ? 85  LEU B C   1 
ATOM   3371  O O   . LEU B 1 85  ? 101.486 140.610 162.293 1.00 40.54  ? 85  LEU B O   1 
ATOM   3372  C CB  . LEU B 1 85  ? 99.660  140.262 165.095 1.00 40.54  ? 85  LEU B CB  1 
ATOM   3373  C CG  . LEU B 1 85  ? 98.365  140.587 165.837 1.00 40.54  ? 85  LEU B CG  1 
ATOM   3374  C CD1 . LEU B 1 85  ? 97.906  139.396 166.659 1.00 40.54  ? 85  LEU B CD1 1 
ATOM   3375  C CD2 . LEU B 1 85  ? 98.556  141.804 166.721 1.00 40.54  ? 85  LEU B CD2 1 
ATOM   3376  N N   . ASP B 1 86  ? 102.556 140.738 164.273 1.00 43.03  ? 86  ASP B N   1 
ATOM   3377  C CA  . ASP B 1 86  ? 103.814 140.272 163.716 1.00 43.03  ? 86  ASP B CA  1 
ATOM   3378  C C   . ASP B 1 86  ? 103.665 138.835 163.226 1.00 43.03  ? 86  ASP B C   1 
ATOM   3379  O O   . ASP B 1 86  ? 103.065 138.002 163.916 1.00 43.03  ? 86  ASP B O   1 
ATOM   3380  C CB  . ASP B 1 86  ? 104.929 140.361 164.758 1.00 43.03  ? 86  ASP B CB  1 
ATOM   3381  C CG  . ASP B 1 86  ? 106.220 140.914 164.185 1.00 43.03  ? 86  ASP B CG  1 
ATOM   3382  O OD1 . ASP B 1 86  ? 106.191 141.454 163.060 1.00 43.03  ? 86  ASP B OD1 1 
ATOM   3383  O OD2 . ASP B 1 86  ? 107.265 140.812 164.861 1.00 43.03  ? 86  ASP B OD2 1 
ATOM   3384  N N   . PRO B 1 87  ? 104.189 138.511 162.045 1.00 37.29  ? 87  PRO B N   1 
ATOM   3385  C CA  . PRO B 1 87  ? 104.100 137.128 161.557 1.00 37.29  ? 87  PRO B CA  1 
ATOM   3386  C C   . PRO B 1 87  ? 104.825 136.124 162.432 1.00 37.29  ? 87  PRO B C   1 
ATOM   3387  O O   . PRO B 1 87  ? 104.584 134.920 162.289 1.00 37.29  ? 87  PRO B O   1 
ATOM   3388  C CB  . PRO B 1 87  ? 104.733 137.207 160.161 1.00 37.29  ? 87  PRO B CB  1 
ATOM   3389  C CG  . PRO B 1 87  ? 104.610 138.638 159.770 1.00 37.29  ? 87  PRO B CG  1 
ATOM   3390  C CD  . PRO B 1 87  ? 104.749 139.420 161.034 1.00 37.29  ? 87  PRO B CD  1 
ATOM   3391  N N   . SER B 1 88  ? 105.718 136.570 163.319 1.00 44.11  ? 88  SER B N   1 
ATOM   3392  C CA  . SER B 1 88  ? 106.440 135.636 164.171 1.00 44.11  ? 88  SER B CA  1 
ATOM   3393  C C   . SER B 1 88  ? 105.531 134.937 165.172 1.00 44.11  ? 88  SER B C   1 
ATOM   3394  O O   . SER B 1 88  ? 105.906 133.885 165.699 1.00 44.11  ? 88  SER B O   1 
ATOM   3395  C CB  . SER B 1 88  ? 107.572 136.359 164.899 1.00 44.11  ? 88  SER B CB  1 
ATOM   3396  O OG  . SER B 1 88  ? 108.781 136.250 164.175 1.00 44.11  ? 88  SER B OG  1 
ATOM   3397  N N   . MET B 1 89  ? 104.350 135.481 165.437 1.00 47.62  ? 89  MET B N   1 
ATOM   3398  C CA  . MET B 1 89  ? 103.410 134.829 166.339 1.00 47.62  ? 89  MET B CA  1 
ATOM   3399  C C   . MET B 1 89  ? 102.600 133.734 165.656 1.00 47.62  ? 89  MET B C   1 
ATOM   3400  O O   . MET B 1 89  ? 101.819 133.052 166.327 1.00 47.62  ? 89  MET B O   1 
ATOM   3401  C CB  . MET B 1 89  ? 102.466 135.862 166.958 1.00 47.62  ? 89  MET B CB  1 
ATOM   3402  C CG  . MET B 1 89  ? 103.031 136.780 168.074 1.00 47.62  ? 89  MET B CG  1 
ATOM   3403  S SD  . MET B 1 89  ? 104.055 136.133 169.436 1.00 47.62  ? 89  MET B SD  1 
ATOM   3404  C CE  . MET B 1 89  ? 105.615 135.683 168.679 1.00 47.62  ? 89  MET B CE  1 
ATOM   3405  N N   . LEU B 1 90  ? 102.784 133.544 164.350 1.00 42.28  ? 90  LEU B N   1 
ATOM   3406  C CA  . LEU B 1 90  ? 102.049 132.531 163.611 1.00 42.28  ? 90  LEU B CA  1 
ATOM   3407  C C   . LEU B 1 90  ? 102.418 131.113 164.016 1.00 42.28  ? 90  LEU B C   1 
ATOM   3408  O O   . LEU B 1 90  ? 101.700 130.179 163.645 1.00 42.28  ? 90  LEU B O   1 
ATOM   3409  C CB  . LEU B 1 90  ? 102.283 132.711 162.113 1.00 42.28  ? 90  LEU B CB  1 
ATOM   3410  C CG  . LEU B 1 90  ? 101.065 133.140 161.304 1.00 42.28  ? 90  LEU B CG  1 
ATOM   3411  C CD1 . LEU B 1 90  ? 101.446 133.344 159.861 1.00 42.28  ? 90  LEU B CD1 1 
ATOM   3412  C CD2 . LEU B 1 90  ? 99.977  132.088 161.420 1.00 42.28  ? 90  LEU B CD2 1 
ATOM   3413  N N   . ASP B 1 91  ? 103.507 130.926 164.752 1.00 50.24  ? 91  ASP B N   1 
ATOM   3414  C CA  . ASP B 1 91  ? 103.879 129.604 165.229 1.00 50.24  ? 91  ASP B CA  1 
ATOM   3415  C C   . ASP B 1 91  ? 103.267 129.274 166.583 1.00 50.24  ? 91  ASP B C   1 
ATOM   3416  O O   . ASP B 1 91  ? 103.396 128.135 167.043 1.00 50.24  ? 91  ASP B O   1 
ATOM   3417  C CB  . ASP B 1 91  ? 105.404 129.481 165.303 1.00 50.24  ? 91  ASP B CB  1 
ATOM   3418  C CG  . ASP B 1 91  ? 106.076 129.763 163.970 1.00 50.24  ? 91  ASP B CG  1 
ATOM   3419  O OD1 . ASP B 1 91  ? 105.360 130.131 163.014 1.00 50.24  ? 91  ASP B OD1 1 
ATOM   3420  O OD2 . ASP B 1 91  ? 107.312 129.612 163.874 1.00 50.24  ? 91  ASP B OD2 1 
ATOM   3421  N N   . SER B 1 92  ? 102.601 130.236 167.223 1.00 49.92  ? 92  SER B N   1 
ATOM   3422  C CA  . SER B 1 92  ? 101.984 130.039 168.528 1.00 49.92  ? 92  SER B CA  1 
ATOM   3423  C C   . SER B 1 92  ? 100.465 130.146 168.470 1.00 49.92  ? 92  SER B C   1 
ATOM   3424  O O   . SER B 1 92  ? 99.826  130.428 169.488 1.00 49.92  ? 92  SER B O   1 
ATOM   3425  C CB  . SER B 1 92  ? 102.549 131.041 169.534 1.00 49.92  ? 92  SER B CB  1 
ATOM   3426  O OG  . SER B 1 92  ? 102.019 130.817 170.828 1.00 49.92  ? 92  SER B OG  1 
ATOM   3427  N N   . ILE B 1 93  ? 99.874  129.927 167.300 1.00 44.08  ? 93  ILE B N   1 
ATOM   3428  C CA  . ILE B 1 93  ? 98.433  130.003 167.106 1.00 44.08  ? 93  ILE B CA  1 
ATOM   3429  C C   . ILE B 1 93  ? 98.005  128.799 166.280 1.00 44.08  ? 93  ILE B C   1 
ATOM   3430  O O   . ILE B 1 93  ? 98.741  128.352 165.393 1.00 44.08  ? 93  ILE B O   1 
ATOM   3431  C CB  . ILE B 1 93  ? 98.027  131.325 166.420 1.00 44.08  ? 93  ILE B CB  1 
ATOM   3432  C CG1 . ILE B 1 93  ? 96.522  131.378 166.168 1.00 44.08  ? 93  ILE B CG1 1 
ATOM   3433  C CG2 . ILE B 1 93  ? 98.781  131.505 165.116 1.00 44.08  ? 93  ILE B CG2 1 
ATOM   3434  C CD1 . ILE B 1 93  ? 96.099  132.545 165.302 1.00 44.08  ? 93  ILE B CD1 1 
ATOM   3435  N N   . TRP B 1 94  ? 96.831  128.254 166.589 1.00 41.48  ? 94  TRP B N   1 
ATOM   3436  C CA  . TRP B 1 94  ? 96.328  127.101 165.853 1.00 41.48  ? 94  TRP B CA  1 
ATOM   3437  C C   . TRP B 1 94  ? 96.198  127.432 164.373 1.00 41.48  ? 94  TRP B C   1 
ATOM   3438  O O   . TRP B 1 94  ? 95.592  128.439 164.000 1.00 41.48  ? 94  TRP B O   1 
ATOM   3439  C CB  . TRP B 1 94  ? 94.977  126.669 166.415 1.00 41.48  ? 94  TRP B CB  1 
ATOM   3440  C CG  . TRP B 1 94  ? 94.492  125.354 165.898 1.00 41.48  ? 94  TRP B CG  1 
ATOM   3441  C CD1 . TRP B 1 94  ? 94.761  124.123 166.414 1.00 41.48  ? 94  TRP B CD1 1 
ATOM   3442  C CD2 . TRP B 1 94  ? 93.642  125.138 164.767 1.00 41.48  ? 94  TRP B CD2 1 
ATOM   3443  N NE1 . TRP B 1 94  ? 94.134  123.152 165.674 1.00 41.48  ? 94  TRP B NE1 1 
ATOM   3444  C CE2 . TRP B 1 94  ? 93.440  123.750 164.657 1.00 41.48  ? 94  TRP B CE2 1 
ATOM   3445  C CE3 . TRP B 1 94  ? 93.033  125.982 163.838 1.00 41.48  ? 94  TRP B CE3 1 
ATOM   3446  C CZ2 . TRP B 1 94  ? 92.658  123.189 163.655 1.00 41.48  ? 94  TRP B CZ2 1 
ATOM   3447  C CZ3 . TRP B 1 94  ? 92.257  125.422 162.845 1.00 41.48  ? 94  TRP B CZ3 1 
ATOM   3448  C CH2 . TRP B 1 94  ? 92.076  124.040 162.761 1.00 41.48  ? 94  TRP B CH2 1 
ATOM   3449  N N   . LYS B 1 95  ? 96.772  126.580 163.529 1.00 38.24  ? 95  LYS B N   1 
ATOM   3450  C CA  . LYS B 1 95  ? 96.726  126.759 162.084 1.00 38.24  ? 95  LYS B CA  1 
ATOM   3451  C C   . LYS B 1 95  ? 96.105  125.524 161.451 1.00 38.24  ? 95  LYS B C   1 
ATOM   3452  O O   . LYS B 1 95  ? 96.594  124.406 161.683 1.00 38.24  ? 95  LYS B O   1 
ATOM   3453  C CB  . LYS B 1 95  ? 98.123  127.001 161.513 1.00 38.24  ? 95  LYS B CB  1 
ATOM   3454  C CG  . LYS B 1 95  ? 98.857  128.175 162.124 1.00 38.24  ? 95  LYS B CG  1 
ATOM   3455  C CD  . LYS B 1 95  ? 100.134 128.469 161.360 1.00 38.24  ? 95  LYS B CD  1 
ATOM   3456  C CE  . LYS B 1 95  ? 100.979 127.220 161.188 1.00 38.24  ? 95  LYS B CE  1 
ATOM   3457  N NZ  . LYS B 1 95  ? 101.371 126.635 162.498 1.00 38.24  ? 95  LYS B NZ  1 
ATOM   3458  N N   . PRO B 1 96  ? 95.043  125.662 160.662 1.00 35.21  ? 96  PRO B N   1 
ATOM   3459  C CA  . PRO B 1 96  ? 94.426  124.482 160.053 1.00 35.21  ? 96  PRO B CA  1 
ATOM   3460  C C   . PRO B 1 96  ? 95.379  123.783 159.097 1.00 35.21  ? 96  PRO B C   1 
ATOM   3461  O O   . PRO B 1 96  ? 96.161  124.421 158.389 1.00 35.21  ? 96  PRO B O   1 
ATOM   3462  C CB  . PRO B 1 96  ? 93.211  125.058 159.319 1.00 35.21  ? 96  PRO B CB  1 
ATOM   3463  C CG  . PRO B 1 96  ? 93.576  126.472 159.057 1.00 35.21  ? 96  PRO B CG  1 
ATOM   3464  C CD  . PRO B 1 96  ? 94.392  126.908 160.233 1.00 35.21  ? 96  PRO B CD  1 
ATOM   3465  N N   . ASP B 1 97  ? 95.309  122.456 159.091 1.00 37.15  ? 97  ASP B N   1 
ATOM   3466  C CA  . ASP B 1 97  ? 96.075  121.664 158.142 1.00 37.15  ? 97  ASP B CA  1 
ATOM   3467  C C   . ASP B 1 97  ? 95.529  121.869 156.736 1.00 37.15  ? 97  ASP B C   1 
ATOM   3468  O O   . ASP B 1 97  ? 94.315  121.892 156.522 1.00 37.15  ? 97  ASP B O   1 
ATOM   3469  C CB  . ASP B 1 97  ? 96.016  120.187 158.530 1.00 37.15  ? 97  ASP B CB  1 
ATOM   3470  C CG  . ASP B 1 97  ? 96.891  119.306 157.658 1.00 37.15  ? 97  ASP B CG  1 
ATOM   3471  O OD1 . ASP B 1 97  ? 97.449  119.795 156.655 1.00 37.15  ? 97  ASP B OD1 1 
ATOM   3472  O OD2 . ASP B 1 97  ? 97.022  118.109 157.983 1.00 37.15  ? 97  ASP B OD2 1 
ATOM   3473  N N   . LEU B 1 98  ? 96.435  122.019 155.773 1.00 33.27  ? 98  LEU B N   1 
ATOM   3474  C CA  . LEU B 1 98  ? 96.032  122.223 154.384 1.00 33.27  ? 98  LEU B CA  1 
ATOM   3475  C C   . LEU B 1 98  ? 97.203  121.838 153.493 1.00 33.27  ? 98  LEU B C   1 
ATOM   3476  O O   . LEU B 1 98  ? 98.226  122.528 153.491 1.00 33.27  ? 98  LEU B O   1 
ATOM   3477  C CB  . LEU B 1 98  ? 95.614  123.667 154.151 1.00 33.27  ? 98  LEU B CB  1 
ATOM   3478  C CG  . LEU B 1 98  ? 94.911  123.997 152.835 1.00 33.27  ? 98  LEU B CG  1 
ATOM   3479  C CD1 . LEU B 1 98  ? 93.910  125.114 153.048 1.00 33.27  ? 98  LEU B CD1 1 
ATOM   3480  C CD2 . LEU B 1 98  ? 95.915  124.392 151.771 1.00 33.27  ? 98  LEU B CD2 1 
ATOM   3481  N N   . PHE B 1 99  ? 97.052  120.756 152.739 1.00 32.34  ? 99  PHE B N   1 
ATOM   3482  C CA  . PHE B 1 99  ? 98.073  120.315 151.803 1.00 32.34  ? 99  PHE B CA  1 
ATOM   3483  C C   . PHE B 1 99  ? 97.434  120.090 150.444 1.00 32.34  ? 99  PHE B C   1 
ATOM   3484  O O   . PHE B 1 99  ? 96.309  119.592 150.353 1.00 32.34  ? 99  PHE B O   1 
ATOM   3485  C CB  . PHE B 1 99  ? 98.762  119.033 152.282 1.00 32.34  ? 99  PHE B CB  1 
ATOM   3486  C CG  . PHE B 1 99  ? 97.972  117.783 152.023 1.00 32.34  ? 99  PHE B CG  1 
ATOM   3487  C CD1 . PHE B 1 99  ? 96.867  117.473 152.791 1.00 32.34  ? 99  PHE B CD1 1 
ATOM   3488  C CD2 . PHE B 1 99  ? 98.339  116.915 151.011 1.00 32.34  ? 99  PHE B CD2 1 
ATOM   3489  C CE1 . PHE B 1 99  ? 96.145  116.325 152.553 1.00 32.34  ? 99  PHE B CE1 1 
ATOM   3490  C CE2 . PHE B 1 99  ? 97.617  115.767 150.771 1.00 32.34  ? 99  PHE B CE2 1 
ATOM   3491  C CZ  . PHE B 1 99  ? 96.520  115.473 151.543 1.00 32.34  ? 99  PHE B CZ  1 
ATOM   3492  N N   . PHE B 1 100 ? 98.149  120.465 149.390 1.00 30.10  ? 100 PHE B N   1 
ATOM   3493  C CA  . PHE B 1 100 ? 97.646  120.293 148.035 1.00 30.10  ? 100 PHE B CA  1 
ATOM   3494  C C   . PHE B 1 100 ? 97.831  118.841 147.614 1.00 30.10  ? 100 PHE B C   1 
ATOM   3495  O O   . PHE B 1 100 ? 98.948  118.317 147.655 1.00 30.10  ? 100 PHE B O   1 
ATOM   3496  C CB  . PHE B 1 100 ? 98.365  121.243 147.083 1.00 30.10  ? 100 PHE B CB  1 
ATOM   3497  C CG  . PHE B 1 100 ? 98.302  122.678 147.511 1.00 30.10  ? 100 PHE B CG  1 
ATOM   3498  C CD1 . PHE B 1 100 ? 97.248  123.482 147.128 1.00 30.10  ? 100 PHE B CD1 1 
ATOM   3499  C CD2 . PHE B 1 100 ? 99.293  123.221 148.305 1.00 30.10  ? 100 PHE B CD2 1 
ATOM   3500  C CE1 . PHE B 1 100 ? 97.184  124.799 147.524 1.00 30.10  ? 100 PHE B CE1 1 
ATOM   3501  C CE2 . PHE B 1 100 ? 99.233  124.537 148.702 1.00 30.10  ? 100 PHE B CE2 1 
ATOM   3502  C CZ  . PHE B 1 100 ? 98.178  125.326 148.312 1.00 30.10  ? 100 PHE B CZ  1 
ATOM   3503  N N   . ALA B 1 101 ? 96.735  118.189 147.222 1.00 28.71  ? 101 ALA B N   1 
ATOM   3504  C CA  . ALA B 1 101 ? 96.786  116.756 146.954 1.00 28.71  ? 101 ALA B CA  1 
ATOM   3505  C C   . ALA B 1 101 ? 97.696  116.437 145.776 1.00 28.71  ? 101 ALA B C   1 
ATOM   3506  O O   . ALA B 1 101 ? 98.460  115.467 145.820 1.00 28.71  ? 101 ALA B O   1 
ATOM   3507  C CB  . ALA B 1 101 ? 95.380  116.217 146.701 1.00 28.71  ? 101 ALA B CB  1 
ATOM   3508  N N   . ASN B 1 102 ? 97.634  117.236 144.718 1.00 30.17  ? 102 ASN B N   1 
ATOM   3509  C CA  . ASN B 1 102 ? 98.395  116.981 143.497 1.00 30.17  ? 102 ASN B CA  1 
ATOM   3510  C C   . ASN B 1 102 ? 99.440  118.081 143.332 1.00 30.17  ? 102 ASN B C   1 
ATOM   3511  O O   . ASN B 1 102 ? 99.172  119.133 142.752 1.00 30.17  ? 102 ASN B O   1 
ATOM   3512  C CB  . ASN B 1 102 ? 97.470  116.896 142.285 1.00 30.17  ? 102 ASN B CB  1 
ATOM   3513  C CG  . ASN B 1 102 ? 96.541  118.085 142.173 1.00 30.17  ? 102 ASN B CG  1 
ATOM   3514  O OD1 . ASN B 1 102 ? 96.160  118.684 143.176 1.00 30.17  ? 102 ASN B OD1 1 
ATOM   3515  N ND2 . ASN B 1 102 ? 96.177  118.438 140.948 1.00 30.17  ? 102 ASN B ND2 1 
ATOM   3516  N N   . GLU B 1 103 ? 100.641 117.828 143.844 1.00 31.65  ? 103 GLU B N   1 
ATOM   3517  C CA  . GLU B 1 103 ? 101.761 118.742 143.647 1.00 31.65  ? 103 GLU B CA  1 
ATOM   3518  C C   . GLU B 1 103 ? 103.056 117.961 143.788 1.00 31.65  ? 103 GLU B C   1 
ATOM   3519  O O   . GLU B 1 103 ? 103.310 117.360 144.835 1.00 31.65  ? 103 GLU B O   1 
ATOM   3520  C CB  . GLU B 1 103 ? 101.713 119.906 144.638 1.00 31.65  ? 103 GLU B CB  1 
ATOM   3521  C CG  . GLU B 1 103 ? 101.424 119.508 146.066 1.00 31.65  ? 103 GLU B CG  1 
ATOM   3522  C CD  . GLU B 1 103 ? 102.624 119.690 146.965 1.00 31.65  ? 103 GLU B CD  1 
ATOM   3523  O OE1 . GLU B 1 103 ? 103.686 120.099 146.453 1.00 31.65  ? 103 GLU B OE1 1 
ATOM   3524  O OE2 . GLU B 1 103 ? 102.508 119.426 148.180 1.00 31.65  ? 103 GLU B OE2 1 
ATOM   3525  N N   . LYS B 1 104 ? 103.866 117.963 142.728 1.00 34.81  ? 104 LYS B N   1 
ATOM   3526  C CA  . LYS B 1 104 ? 105.125 117.228 142.759 1.00 34.81  ? 104 LYS B CA  1 
ATOM   3527  C C   . LYS B 1 104 ? 106.078 117.812 143.792 1.00 34.81  ? 104 LYS B C   1 
ATOM   3528  O O   . LYS B 1 104 ? 106.795 117.070 144.473 1.00 34.81  ? 104 LYS B O   1 
ATOM   3529  C CB  . LYS B 1 104 ? 105.761 117.229 141.372 1.00 34.81  ? 104 LYS B CB  1 
ATOM   3530  C CG  . LYS B 1 104 ? 104.841 116.723 140.276 1.00 34.81  ? 104 LYS B CG  1 
ATOM   3531  C CD  . LYS B 1 104 ? 105.617 115.986 139.201 1.00 34.81  ? 104 LYS B CD  1 
ATOM   3532  C CE  . LYS B 1 104 ? 104.690 115.422 138.140 1.00 34.81  ? 104 LYS B CE  1 
ATOM   3533  N NZ  . LYS B 1 104 ? 103.684 114.495 138.721 1.00 34.81  ? 104 LYS B NZ  1 
ATOM   3534  N N   . GLY B 1 105 ? 106.106 119.134 143.921 1.00 31.32  ? 105 GLY B N   1 
ATOM   3535  C CA  . GLY B 1 105 ? 106.950 119.777 144.906 1.00 31.32  ? 105 GLY B CA  1 
ATOM   3536  C C   . GLY B 1 105 ? 106.573 121.223 145.144 1.00 31.32  ? 105 GLY B C   1 
ATOM   3537  O O   . GLY B 1 105 ? 106.413 121.993 144.193 1.00 31.32  ? 105 GLY B O   1 
ATOM   3538  N N   . ALA B 1 106 ? 106.429 121.605 146.409 1.00 28.73  ? 106 ALA B N   1 
ATOM   3539  C CA  . ALA B 1 106 ? 106.069 122.966 146.770 1.00 28.73  ? 106 ALA B CA  1 
ATOM   3540  C C   . ALA B 1 106 ? 106.958 123.425 147.915 1.00 28.73  ? 106 ALA B C   1 
ATOM   3541  O O   . ALA B 1 106 ? 107.486 122.614 148.678 1.00 28.73  ? 106 ALA B O   1 
ATOM   3542  C CB  . ALA B 1 106 ? 104.593 123.077 147.165 1.00 28.73  ? 106 ALA B CB  1 
ATOM   3543  N N   . ASN B 1 107 ? 107.120 124.740 148.027 1.00 28.43  ? 107 ASN B N   1 
ATOM   3544  C CA  . ASN B 1 107 ? 107.985 125.304 149.049 1.00 28.43  ? 107 ASN B CA  1 
ATOM   3545  C C   . ASN B 1 107 ? 107.474 126.680 149.440 1.00 28.43  ? 107 ASN B C   1 
ATOM   3546  O O   . ASN B 1 107 ? 106.751 127.333 148.686 1.00 28.43  ? 107 ASN B O   1 
ATOM   3547  C CB  . ASN B 1 107 ? 109.434 125.400 148.565 1.00 28.43  ? 107 ASN B CB  1 
ATOM   3548  C CG  . ASN B 1 107 ? 109.577 126.285 147.350 1.00 28.43  ? 107 ASN B CG  1 
ATOM   3549  O OD1 . ASN B 1 107 ? 108.632 126.455 146.582 1.00 28.43  ? 107 ASN B OD1 1 
ATOM   3550  N ND2 . ASN B 1 107 ? 110.760 126.856 147.166 1.00 28.43  ? 107 ASN B ND2 1 
ATOM   3551  N N   . PHE B 1 108 ? 107.868 127.116 150.633 1.00 32.28  ? 108 PHE B N   1 
ATOM   3552  C CA  . PHE B 1 108 ? 107.543 128.455 151.096 1.00 32.28  ? 108 PHE B CA  1 
ATOM   3553  C C   . PHE B 1 108 ? 108.432 129.474 150.392 1.00 32.28  ? 108 PHE B C   1 
ATOM   3554  O O   . PHE B 1 108 ? 109.217 129.147 149.499 1.00 32.28  ? 108 PHE B O   1 
ATOM   3555  C CB  . PHE B 1 108 ? 107.715 128.561 152.608 1.00 32.28  ? 108 PHE B CB  1 
ATOM   3556  C CG  . PHE B 1 108 ? 106.842 127.630 153.389 1.00 32.28  ? 108 PHE B CG  1 
ATOM   3557  C CD1 . PHE B 1 108 ? 107.271 126.353 153.690 1.00 32.28  ? 108 PHE B CD1 1 
ATOM   3558  C CD2 . PHE B 1 108 ? 105.601 128.037 153.838 1.00 32.28  ? 108 PHE B CD2 1 
ATOM   3559  C CE1 . PHE B 1 108 ? 106.475 125.497 154.415 1.00 32.28  ? 108 PHE B CE1 1 
ATOM   3560  C CE2 . PHE B 1 108 ? 104.803 127.183 154.564 1.00 32.28  ? 108 PHE B CE2 1 
ATOM   3561  C CZ  . PHE B 1 108 ? 105.239 125.913 154.852 1.00 32.28  ? 108 PHE B CZ  1 
ATOM   3562  N N   . HIS B 1 109 ? 108.315 130.730 150.810 1.00 36.30  ? 109 HIS B N   1 
ATOM   3563  C CA  . HIS B 1 109 ? 109.168 131.798 150.307 1.00 36.30  ? 109 HIS B CA  1 
ATOM   3564  C C   . HIS B 1 109 ? 109.613 132.646 151.483 1.00 36.30  ? 109 HIS B C   1 
ATOM   3565  O O   . HIS B 1 109 ? 108.778 133.250 152.162 1.00 36.30  ? 109 HIS B O   1 
ATOM   3566  C CB  . HIS B 1 109 ? 108.438 132.660 149.276 1.00 36.30  ? 109 HIS B CB  1 
ATOM   3567  C CG  . HIS B 1 109 ? 108.670 132.237 147.861 1.00 36.30  ? 109 HIS B CG  1 
ATOM   3568  N ND1 . HIS B 1 109 ? 108.132 132.911 146.787 1.00 36.30  ? 109 HIS B ND1 1 
ATOM   3569  C CD2 . HIS B 1 109 ? 109.385 131.212 147.342 1.00 36.30  ? 109 HIS B CD2 1 
ATOM   3570  C CE1 . HIS B 1 109 ? 108.504 132.319 145.667 1.00 36.30  ? 109 HIS B CE1 1 
ATOM   3571  N NE2 . HIS B 1 109 ? 109.263 131.284 145.976 1.00 36.30  ? 109 HIS B NE2 1 
ATOM   3572  N N   . GLU B 1 110 ? 110.920 132.694 151.724 1.00 36.15  ? 110 GLU B N   1 
ATOM   3573  C CA  . GLU B 1 110 ? 111.484 133.531 152.774 1.00 36.15  ? 110 GLU B CA  1 
ATOM   3574  C C   . GLU B 1 110 ? 112.533 134.444 152.155 1.00 36.15  ? 110 GLU B C   1 
ATOM   3575  O O   . GLU B 1 110 ? 113.456 133.976 151.480 1.00 36.15  ? 110 GLU B O   1 
ATOM   3576  C CB  . GLU B 1 110 ? 112.058 132.675 153.916 1.00 36.15  ? 110 GLU B CB  1 
ATOM   3577  C CG  . GLU B 1 110 ? 113.536 132.283 153.847 1.00 36.15  ? 110 GLU B CG  1 
ATOM   3578  C CD  . GLU B 1 110 ? 113.869 131.319 152.713 1.00 36.15  ? 110 GLU B CD  1 
ATOM   3579  O OE1 . GLU B 1 110 ? 115.019 130.833 152.672 1.00 36.15  ? 110 GLU B OE1 1 
ATOM   3580  O OE2 . GLU B 1 110 ? 112.993 131.040 151.867 1.00 36.15  ? 110 GLU B OE2 1 
ATOM   3581  N N   . VAL B 1 111 ? 112.341 135.751 152.317 1.00 32.23  ? 111 VAL B N   1 
ATOM   3582  C CA  . VAL B 1 111 ? 113.313 136.752 151.898 1.00 32.23  ? 111 VAL B CA  1 
ATOM   3583  C C   . VAL B 1 111 ? 113.226 137.922 152.866 1.00 32.23  ? 111 VAL B C   1 
ATOM   3584  O O   . VAL B 1 111 ? 112.192 138.592 152.950 1.00 32.23  ? 111 VAL B O   1 
ATOM   3585  C CB  . VAL B 1 111 ? 113.076 137.202 150.447 1.00 32.23  ? 111 VAL B CB  1 
ATOM   3586  C CG1 . VAL B 1 111 ? 113.851 136.323 149.487 1.00 32.23  ? 111 VAL B CG1 1 
ATOM   3587  C CG2 . VAL B 1 111 ? 111.599 137.150 150.120 1.00 32.23  ? 111 VAL B CG2 1 
ATOM   3588  N N   . THR B 1 112 ? 114.289 138.133 153.642 1.00 36.62  ? 112 THR B N   1 
ATOM   3589  C CA  . THR B 1 112 ? 114.407 139.199 154.636 1.00 36.62  ? 112 THR B CA  1 
ATOM   3590  C C   . THR B 1 112 ? 113.424 139.006 155.785 1.00 36.62  ? 112 THR B C   1 
ATOM   3591  O O   . THR B 1 112 ? 113.493 139.718 156.791 1.00 36.62  ? 112 THR B O   1 
ATOM   3592  C CB  . THR B 1 112 ? 114.204 140.581 154.003 1.00 36.62  ? 112 THR B CB  1 
ATOM   3593  O OG1 . THR B 1 112 ? 112.834 140.735 153.614 1.00 36.62  ? 112 THR B OG1 1 
ATOM   3594  C CG2 . THR B 1 112 ? 115.093 140.751 152.785 1.00 36.62  ? 112 THR B CG2 1 
ATOM   3595  N N   . THR B 1 113 ? 112.524 138.041 155.645 1.00 38.86  ? 113 THR B N   1 
ATOM   3596  C CA  . THR B 1 113 ? 111.546 137.629 156.650 1.00 38.86  ? 113 THR B CA  1 
ATOM   3597  C C   . THR B 1 113 ? 110.839 136.398 156.098 1.00 38.86  ? 113 THR B C   1 
ATOM   3598  O O   . THR B 1 113 ? 111.215 135.870 155.045 1.00 38.86  ? 113 THR B O   1 
ATOM   3599  C CB  . THR B 1 113 ? 110.545 138.737 156.987 1.00 38.86  ? 113 THR B CB  1 
ATOM   3600  O OG1 . THR B 1 113 ? 110.609 139.771 155.998 1.00 38.86  ? 113 THR B OG1 1 
ATOM   3601  C CG2 . THR B 1 113 ? 110.824 139.318 158.369 1.00 38.86  ? 113 THR B CG2 1 
ATOM   3602  N N   . ASP B 1 114 ? 109.814 135.939 156.806 1.00 39.34  ? 114 ASP B N   1 
ATOM   3603  C CA  . ASP B 1 114 ? 108.906 134.926 156.291 1.00 39.34  ? 114 ASP B CA  1 
ATOM   3604  C C   . ASP B 1 114 ? 107.695 135.621 155.684 1.00 39.34  ? 114 ASP B C   1 
ATOM   3605  O O   . ASP B 1 114 ? 107.127 136.532 156.295 1.00 39.34  ? 114 ASP B O   1 
ATOM   3606  C CB  . ASP B 1 114 ? 108.473 133.957 157.391 1.00 39.34  ? 114 ASP B CB  1 
ATOM   3607  C CG  . ASP B 1 114 ? 109.141 132.601 157.269 1.00 39.34  ? 114 ASP B CG  1 
ATOM   3608  O OD1 . ASP B 1 114 ? 110.124 132.489 156.508 1.00 39.34  ? 114 ASP B OD1 1 
ATOM   3609  O OD2 . ASP B 1 114 ? 108.679 131.646 157.926 1.00 39.34  ? 114 ASP B OD2 1 
ATOM   3610  N N   . ASN B 1 115 ? 107.313 135.203 154.478 1.00 36.10  ? 115 ASN B N   1 
ATOM   3611  C CA  . ASN B 1 115 ? 106.193 135.812 153.761 1.00 36.10  ? 115 ASN B CA  1 
ATOM   3612  C C   . ASN B 1 115 ? 104.890 135.221 154.290 1.00 36.10  ? 115 ASN B C   1 
ATOM   3613  O O   . ASN B 1 115 ? 104.316 134.284 153.732 1.00 36.10  ? 115 ASN B O   1 
ATOM   3614  C CB  . ASN B 1 115 ? 106.336 135.597 152.262 1.00 36.10  ? 115 ASN B CB  1 
ATOM   3615  C CG  . ASN B 1 115 ? 107.591 136.218 151.710 1.00 36.10  ? 115 ASN B CG  1 
ATOM   3616  O OD1 . ASN B 1 115 ? 108.425 136.720 152.459 1.00 36.10  ? 115 ASN B OD1 1 
ATOM   3617  N ND2 . ASN B 1 115 ? 107.737 136.189 150.393 1.00 36.10  ? 115 ASN B ND2 1 
ATOM   3618  N N   . LYS B 1 116 ? 104.421 135.785 155.399 1.00 33.37  ? 116 LYS B N   1 
ATOM   3619  C CA  . LYS B 1 116 ? 103.167 135.367 156.003 1.00 33.37  ? 116 LYS B CA  1 
ATOM   3620  C C   . LYS B 1 116 ? 102.500 136.578 156.633 1.00 33.37  ? 116 LYS B C   1 
ATOM   3621  O O   . LYS B 1 116 ? 103.178 137.449 157.180 1.00 33.37  ? 116 LYS B O   1 
ATOM   3622  C CB  . LYS B 1 116 ? 103.384 134.276 157.054 1.00 33.37  ? 116 LYS B CB  1 
ATOM   3623  C CG  . LYS B 1 116 ? 103.523 132.878 156.480 1.00 33.37  ? 116 LYS B CG  1 
ATOM   3624  C CD  . LYS B 1 116 ? 103.870 131.859 157.552 1.00 33.37  ? 116 LYS B CD  1 
ATOM   3625  C CE  . LYS B 1 116 ? 105.324 131.969 157.974 1.00 33.37  ? 116 LYS B CE  1 
ATOM   3626  N NZ  . LYS B 1 116 ? 105.758 130.792 158.778 1.00 33.37  ? 116 LYS B NZ  1 
ATOM   3627  N N   . LEU B 1 117 ? 101.175 136.625 156.550 1.00 34.34  ? 117 LEU B N   1 
ATOM   3628  C CA  . LEU B 1 117 ? 100.391 137.719 157.106 1.00 34.34  ? 117 LEU B CA  1 
ATOM   3629  C C   . LEU B 1 117 ? 99.317  137.148 158.015 1.00 34.34  ? 117 LEU B C   1 
ATOM   3630  O O   . LEU B 1 117 ? 98.585  136.237 157.618 1.00 34.34  ? 117 LEU B O   1 
ATOM   3631  C CB  . LEU B 1 117 ? 99.753  138.561 156.000 1.00 34.34  ? 117 LEU B CB  1 
ATOM   3632  C CG  . LEU B 1 117 ? 98.476  139.313 156.363 1.00 34.34  ? 117 LEU B CG  1 
ATOM   3633  C CD1 . LEU B 1 117 ? 98.789  140.474 157.283 1.00 34.34  ? 117 LEU B CD1 1 
ATOM   3634  C CD2 . LEU B 1 117 ? 97.774  139.797 155.112 1.00 34.34  ? 117 LEU B CD2 1 
ATOM   3635  N N   . LEU B 1 118 ? 99.223  137.682 159.228 1.00 36.04  ? 118 LEU B N   1 
ATOM   3636  C CA  . LEU B 1 118 ? 98.246  137.236 160.208 1.00 36.04  ? 118 LEU B CA  1 
ATOM   3637  C C   . LEU B 1 118 ? 97.498  138.439 160.760 1.00 36.04  ? 118 LEU B C   1 
ATOM   3638  O O   . LEU B 1 118 ? 98.094  139.488 161.011 1.00 36.04  ? 118 LEU B O   1 
ATOM   3639  C CB  . LEU B 1 118 ? 98.922  136.440 161.334 1.00 36.04  ? 118 LEU B CB  1 
ATOM   3640  C CG  . LEU B 1 118 ? 98.168  136.189 162.638 1.00 36.04  ? 118 LEU B CG  1 
ATOM   3641  C CD1 . LEU B 1 118 ? 98.590  134.872 163.234 1.00 36.04  ? 118 LEU B CD1 1 
ATOM   3642  C CD2 . LEU B 1 118 ? 98.483  137.289 163.626 1.00 36.04  ? 118 LEU B CD2 1 
ATOM   3643  N N   . ARG B 1 119 ? 96.191  138.280 160.951 1.00 35.01  ? 119 ARG B N   1 
ATOM   3644  C CA  . ARG B 1 119 ? 95.342  139.387 161.357 1.00 35.01  ? 119 ARG B CA  1 
ATOM   3645  C C   . ARG B 1 119 ? 94.196  138.856 162.205 1.00 35.01  ? 119 ARG B C   1 
ATOM   3646  O O   . ARG B 1 119 ? 93.569  137.855 161.852 1.00 35.01  ? 119 ARG B O   1 
ATOM   3647  C CB  . ARG B 1 119 ? 94.809  140.128 160.128 1.00 35.01  ? 119 ARG B CB  1 
ATOM   3648  C CG  . ARG B 1 119 ? 93.839  141.237 160.433 1.00 35.01  ? 119 ARG B CG  1 
ATOM   3649  C CD  . ARG B 1 119 ? 93.461  141.972 159.163 1.00 35.01  ? 119 ARG B CD  1 
ATOM   3650  N NE  . ARG B 1 119 ? 94.630  142.345 158.376 1.00 35.01  ? 119 ARG B NE  1 
ATOM   3651  C CZ  . ARG B 1 119 ? 94.573  142.999 157.225 1.00 35.01  ? 119 ARG B CZ  1 
ATOM   3652  N NH1 . ARG B 1 119 ? 93.417  143.357 156.693 1.00 35.01  ? 119 ARG B NH1 1 
ATOM   3653  N NH2 . ARG B 1 119 ? 95.703  143.303 156.594 1.00 35.01  ? 119 ARG B NH2 1 
ATOM   3654  N N   . ILE B 1 120 ? 93.929  139.528 163.323 1.00 39.08  ? 120 ILE B N   1 
ATOM   3655  C CA  . ILE B 1 120 ? 92.868  139.148 164.253 1.00 39.08  ? 120 ILE B CA  1 
ATOM   3656  C C   . ILE B 1 120 ? 91.846  140.271 164.291 1.00 39.08  ? 120 ILE B C   1 
ATOM   3657  O O   . ILE B 1 120 ? 92.209  141.440 164.461 1.00 39.08  ? 120 ILE B O   1 
ATOM   3658  C CB  . ILE B 1 120 ? 93.386  138.861 165.680 1.00 39.08  ? 120 ILE B CB  1 
ATOM   3659  C CG1 . ILE B 1 120 ? 94.136  137.526 165.815 1.00 39.08  ? 120 ILE B CG1 1 
ATOM   3660  C CG2 . ILE B 1 120 ? 92.245  138.888 166.680 1.00 39.08  ? 120 ILE B CG2 1 
ATOM   3661  C CD1 . ILE B 1 120 ? 95.213  137.230 164.827 1.00 39.08  ? 120 ILE B CD1 1 
ATOM   3662  N N   . PHE B 1 121 ? 90.575  139.918 164.134 1.00 44.50  ? 121 PHE B N   1 
ATOM   3663  C CA  . PHE B 1 121 ? 89.487  140.872 164.271 1.00 44.50  ? 121 PHE B CA  1 
ATOM   3664  C C   . PHE B 1 121 ? 88.920  140.825 165.689 1.00 44.50  ? 121 PHE B C   1 
ATOM   3665  O O   . PHE B 1 121 ? 89.233  139.936 166.483 1.00 44.50  ? 121 PHE B O   1 
ATOM   3666  C CB  . PHE B 1 121 ? 88.396  140.591 163.240 1.00 44.50  ? 121 PHE B CB  1 
ATOM   3667  C CG  . PHE B 1 121 ? 88.879  140.646 161.823 1.00 44.50  ? 121 PHE B CG  1 
ATOM   3668  C CD1 . PHE B 1 121 ? 89.553  141.756 161.354 1.00 44.50  ? 121 PHE B CD1 1 
ATOM   3669  C CD2 . PHE B 1 121 ? 88.647  139.594 160.956 1.00 44.50  ? 121 PHE B CD2 1 
ATOM   3670  C CE1 . PHE B 1 121 ? 89.997  141.813 160.052 1.00 44.50  ? 121 PHE B CE1 1 
ATOM   3671  C CE2 . PHE B 1 121 ? 89.088  139.648 159.650 1.00 44.50  ? 121 PHE B CE2 1 
ATOM   3672  C CZ  . PHE B 1 121 ? 89.763  140.758 159.199 1.00 44.50  ? 121 PHE B CZ  1 
ATOM   3673  N N   . LYS B 1 122 ? 88.073  141.807 166.006 1.00 52.59  ? 122 LYS B N   1 
ATOM   3674  C CA  . LYS B 1 122 ? 87.579  141.935 167.374 1.00 52.59  ? 122 LYS B CA  1 
ATOM   3675  C C   . LYS B 1 122 ? 86.680  140.767 167.765 1.00 52.59  ? 122 LYS B C   1 
ATOM   3676  O O   . LYS B 1 122 ? 86.766  140.265 168.891 1.00 52.59  ? 122 LYS B O   1 
ATOM   3677  C CB  . LYS B 1 122 ? 86.836  143.258 167.547 1.00 52.59  ? 122 LYS B CB  1 
ATOM   3678  C CG  . LYS B 1 122 ? 86.621  143.647 168.999 1.00 52.59  ? 122 LYS B CG  1 
ATOM   3679  C CD  . LYS B 1 122 ? 86.015  145.032 169.119 1.00 52.59  ? 122 LYS B CD  1 
ATOM   3680  C CE  . LYS B 1 122 ? 86.274  145.610 170.496 1.00 52.59  ? 122 LYS B CE  1 
ATOM   3681  N NZ  . LYS B 1 122 ? 86.058  144.592 171.561 1.00 52.59  ? 122 LYS B NZ  1 
ATOM   3682  N N   . ASN B 1 123 ? 85.804  140.329 166.857 1.00 46.74  ? 123 ASN B N   1 
ATOM   3683  C CA  . ASN B 1 123 ? 84.873  139.257 167.197 1.00 46.74  ? 123 ASN B CA  1 
ATOM   3684  C C   . ASN B 1 123 ? 85.606  137.949 167.464 1.00 46.74  ? 123 ASN B C   1 
ATOM   3685  O O   . ASN B 1 123 ? 85.228  137.193 168.366 1.00 46.74  ? 123 ASN B O   1 
ATOM   3686  C CB  . ASN B 1 123 ? 83.838  139.083 166.086 1.00 46.74  ? 123 ASN B CB  1 
ATOM   3687  C CG  . ASN B 1 123 ? 84.465  138.937 164.714 1.00 46.74  ? 123 ASN B CG  1 
ATOM   3688  O OD1 . ASN B 1 123 ? 85.553  138.381 164.568 1.00 46.74  ? 123 ASN B OD1 1 
ATOM   3689  N ND2 . ASN B 1 123 ? 83.776  139.437 163.695 1.00 46.74  ? 123 ASN B ND2 1 
ATOM   3690  N N   . GLY B 1 124 ? 86.651  137.666 166.694 1.00 38.21  ? 124 GLY B N   1 
ATOM   3691  C CA  . GLY B 1 124 ? 87.417  136.451 166.879 1.00 38.21  ? 124 GLY B CA  1 
ATOM   3692  C C   . GLY B 1 124 ? 87.885  135.848 165.574 1.00 38.21  ? 124 GLY B C   1 
ATOM   3693  O O   . GLY B 1 124 ? 88.715  134.935 165.569 1.00 38.21  ? 124 GLY B O   1 
ATOM   3694  N N   . ASN B 1 125 ? 87.360  136.351 164.459 1.00 38.01  ? 125 ASN B N   1 
ATOM   3695  C CA  . ASN B 1 125 ? 87.765  135.848 163.154 1.00 38.01  ? 125 ASN B CA  1 
ATOM   3696  C C   . ASN B 1 125 ? 89.242  136.127 162.916 1.00 38.01  ? 125 ASN B C   1 
ATOM   3697  O O   . ASN B 1 125 ? 89.766  137.172 163.311 1.00 38.01  ? 125 ASN B O   1 
ATOM   3698  C CB  . ASN B 1 125 ? 86.921  136.488 162.054 1.00 38.01  ? 125 ASN B CB  1 
ATOM   3699  C CG  . ASN B 1 125 ? 85.436  136.293 162.272 1.00 38.01  ? 125 ASN B CG  1 
ATOM   3700  O OD1 . ASN B 1 125 ? 85.010  135.324 162.899 1.00 38.01  ? 125 ASN B OD1 1 
ATOM   3701  N ND2 . ASN B 1 125 ? 84.636  137.217 161.754 1.00 38.01  ? 125 ASN B ND2 1 
ATOM   3702  N N   . VAL B 1 126 ? 89.915  135.183 162.266 1.00 32.54  ? 126 VAL B N   1 
ATOM   3703  C CA  . VAL B 1 126 ? 91.349  135.256 162.026 1.00 32.54  ? 126 VAL B CA  1 
ATOM   3704  C C   . VAL B 1 126 ? 91.599  135.156 160.530 1.00 32.54  ? 126 VAL B C   1 
ATOM   3705  O O   . VAL B 1 126 ? 90.958  134.359 159.838 1.00 32.54  ? 126 VAL B O   1 
ATOM   3706  C CB  . VAL B 1 126 ? 92.103  134.140 162.778 1.00 32.54  ? 126 VAL B CB  1 
ATOM   3707  C CG1 . VAL B 1 126 ? 93.595  134.235 162.522 1.00 32.54  ? 126 VAL B CG1 1 
ATOM   3708  C CG2 . VAL B 1 126 ? 91.808  134.212 164.262 1.00 32.54  ? 126 VAL B CG2 1 
ATOM   3709  N N   . LEU B 1 127 ? 92.518  135.975 160.030 1.00 29.07  ? 127 LEU B N   1 
ATOM   3710  C CA  . LEU B 1 127 ? 92.985  135.891 158.655 1.00 29.07  ? 127 LEU B CA  1 
ATOM   3711  C C   . LEU B 1 127 ? 94.430  135.418 158.655 1.00 29.07  ? 127 LEU B C   1 
ATOM   3712  O O   . LEU B 1 127 ? 95.200  135.748 159.561 1.00 29.07  ? 127 LEU B O   1 
ATOM   3713  C CB  . LEU B 1 127 ? 92.875  137.241 157.944 1.00 29.07  ? 127 LEU B CB  1 
ATOM   3714  C CG  . LEU B 1 127 ? 92.779  137.194 156.419 1.00 29.07  ? 127 LEU B CG  1 
ATOM   3715  C CD1 . LEU B 1 127 ? 91.828  138.260 155.915 1.00 29.07  ? 127 LEU B CD1 1 
ATOM   3716  C CD2 . LEU B 1 127 ? 94.144  137.364 155.788 1.00 29.07  ? 127 LEU B CD2 1 
ATOM   3717  N N   . TYR B 1 128 ? 94.796  134.639 157.642 1.00 39.99  ? 128 TYR B N   1 
ATOM   3718  C CA  . TYR B 1 128 ? 96.135  134.057 157.585 1.00 39.99  ? 128 TYR B CA  1 
ATOM   3719  C C   . TYR B 1 128 ? 96.476  133.850 156.113 1.00 39.99  ? 128 TYR B C   1 
ATOM   3720  O O   . TYR B 1 128 ? 96.025  132.880 155.500 1.00 39.99  ? 128 TYR B O   1 
ATOM   3721  C CB  . TYR B 1 128 ? 96.188  132.759 158.379 1.00 39.99  ? 128 TYR B CB  1 
ATOM   3722  C CG  . TYR B 1 128 ? 97.263  131.782 157.966 1.00 39.99  ? 128 TYR B CG  1 
ATOM   3723  C CD1 . TYR B 1 128 ? 98.599  132.048 158.207 1.00 39.99  ? 128 TYR B CD1 1 
ATOM   3724  C CD2 . TYR B 1 128 ? 96.935  130.579 157.359 1.00 39.99  ? 128 TYR B CD2 1 
ATOM   3725  C CE1 . TYR B 1 128 ? 99.581  131.151 157.842 1.00 39.99  ? 128 TYR B CE1 1 
ATOM   3726  C CE2 . TYR B 1 128 ? 97.909  129.678 156.989 1.00 39.99  ? 128 TYR B CE2 1 
ATOM   3727  C CZ  . TYR B 1 128 ? 99.230  129.969 157.233 1.00 39.99  ? 128 TYR B CZ  1 
ATOM   3728  O OH  . TYR B 1 128 ? 100.204 129.073 156.866 1.00 39.99  ? 128 TYR B OH  1 
ATOM   3729  N N   . SER B 1 129 ? 97.254  134.770 155.555 1.00 47.29  ? 129 SER B N   1 
ATOM   3730  C CA  . SER B 1 129 ? 97.628  134.739 154.149 1.00 47.29  ? 129 SER B CA  1 
ATOM   3731  C C   . SER B 1 129 ? 99.097  134.373 154.033 1.00 47.29  ? 129 SER B C   1 
ATOM   3732  O O   . SER B 1 129 ? 99.941  134.960 154.716 1.00 47.29  ? 129 SER B O   1 
ATOM   3733  C CB  . SER B 1 129 ? 97.366  136.086 153.478 1.00 47.29  ? 129 SER B CB  1 
ATOM   3734  O OG  . SER B 1 129 ? 98.499  136.927 153.579 1.00 47.29  ? 129 SER B OG  1 
ATOM   3735  N N   . ILE B 1 130 ? 99.398  133.414 153.167 1.00 49.98  ? 130 ILE B N   1 
ATOM   3736  C CA  . ILE B 1 130 ? 100.741 132.866 153.044 1.00 49.98  ? 130 ILE B CA  1 
ATOM   3737  C C   . ILE B 1 130 ? 101.068 132.711 151.567 1.00 49.98  ? 130 ILE B C   1 
ATOM   3738  O O   . ILE B 1 130 ? 100.197 132.366 150.762 1.00 49.98  ? 130 ILE B O   1 
ATOM   3739  C CB  . ILE B 1 130 ? 100.854 131.525 153.795 1.00 49.98  ? 130 ILE B CB  1 
ATOM   3740  C CG1 . ILE B 1 130 ? 102.191 130.847 153.522 1.00 49.98  ? 130 ILE B CG1 1 
ATOM   3741  C CG2 . ILE B 1 130 ? 99.708  130.609 153.418 1.00 49.98  ? 130 ILE B CG2 1 
ATOM   3742  C CD1 . ILE B 1 130 ? 102.317 129.513 154.198 1.00 49.98  ? 130 ILE B CD1 1 
ATOM   3743  N N   . ARG B 1 131 ? 102.319 132.984 151.207 1.00 47.29  ? 131 ARG B N   1 
ATOM   3744  C CA  . ARG B 1 131 ? 102.766 132.882 149.826 1.00 47.29  ? 131 ARG B CA  1 
ATOM   3745  C C   . ARG B 1 131 ? 103.432 131.536 149.584 1.00 47.29  ? 131 ARG B C   1 
ATOM   3746  O O   . ARG B 1 131 ? 104.224 131.067 150.404 1.00 47.29  ? 131 ARG B O   1 
ATOM   3747  C CB  . ARG B 1 131 ? 103.738 134.012 149.493 1.00 47.29  ? 131 ARG B CB  1 
ATOM   3748  C CG  . ARG B 1 131 ? 104.217 134.010 148.060 1.00 47.29  ? 131 ARG B CG  1 
ATOM   3749  C CD  . ARG B 1 131 ? 104.484 135.421 147.578 1.00 47.29  ? 131 ARG B CD  1 
ATOM   3750  N NE  . ARG B 1 131 ? 105.906 135.682 147.404 1.00 47.29  ? 131 ARG B NE  1 
ATOM   3751  C CZ  . ARG B 1 131 ? 106.536 135.634 146.240 1.00 47.29  ? 131 ARG B CZ  1 
ATOM   3752  N NH1 . ARG B 1 131 ? 105.896 135.341 145.120 1.00 47.29  ? 131 ARG B NH1 1 
ATOM   3753  N NH2 . ARG B 1 131 ? 107.840 135.887 146.197 1.00 47.29  ? 131 ARG B NH2 1 
ATOM   3754  N N   . LEU B 1 132 ? 103.104 130.916 148.454 1.00 46.54  ? 132 LEU B N   1 
ATOM   3755  C CA  . LEU B 1 132 ? 103.639 129.610 148.104 1.00 46.54  ? 132 LEU B CA  1 
ATOM   3756  C C   . LEU B 1 132 ? 103.868 129.540 146.603 1.00 46.54  ? 132 LEU B C   1 
ATOM   3757  O O   . LEU B 1 132 ? 103.312 130.324 145.832 1.00 46.54  ? 132 LEU B O   1 
ATOM   3758  C CB  . LEU B 1 132 ? 102.701 128.474 148.525 1.00 46.54  ? 132 LEU B CB  1 
ATOM   3759  C CG  . LEU B 1 132 ? 102.471 128.226 150.011 1.00 46.54  ? 132 LEU B CG  1 
ATOM   3760  C CD1 . LEU B 1 132 ? 101.195 128.897 150.460 1.00 46.54  ? 132 LEU B CD1 1 
ATOM   3761  C CD2 . LEU B 1 132 ? 102.408 126.738 150.284 1.00 46.54  ? 132 LEU B CD2 1 
ATOM   3762  N N   . THR B 1 133 ? 104.704 128.588 146.197 1.00 27.46  ? 133 THR B N   1 
ATOM   3763  C CA  . THR B 1 133 ? 104.873 128.230 144.794 1.00 27.46  ? 133 THR B CA  1 
ATOM   3764  C C   . THR B 1 133 ? 104.674 126.730 144.672 1.00 27.46  ? 133 THR B C   1 
ATOM   3765  O O   . THR B 1 133 ? 105.380 125.956 145.324 1.00 27.46  ? 133 THR B O   1 
ATOM   3766  C CB  . THR B 1 133 ? 106.251 128.630 144.269 1.00 27.46  ? 133 THR B CB  1 
ATOM   3767  O OG1 . THR B 1 133 ? 107.263 128.106 145.135 1.00 27.46  ? 133 THR B OG1 1 
ATOM   3768  C CG2 . THR B 1 133 ? 106.376 130.137 144.208 1.00 27.46  ? 133 THR B CG2 1 
ATOM   3769  N N   . LEU B 1 134 ? 103.724 126.319 143.840 1.00 27.73  ? 134 LEU B N   1 
ATOM   3770  C CA  . LEU B 1 134 ? 103.336 124.921 143.730 1.00 27.73  ? 134 LEU B CA  1 
ATOM   3771  C C   . LEU B 1 134 ? 103.620 124.413 142.326 1.00 27.73  ? 134 LEU B C   1 
ATOM   3772  O O   . LEU B 1 134 ? 103.280 125.075 141.342 1.00 27.73  ? 134 LEU B O   1 
ATOM   3773  C CB  . LEU B 1 134 ? 101.856 124.738 144.053 1.00 27.73  ? 134 LEU B CB  1 
ATOM   3774  C CG  . LEU B 1 134 ? 101.249 125.688 145.077 1.00 27.73  ? 134 LEU B CG  1 
ATOM   3775  C CD1 . LEU B 1 134 ? 99.760  125.444 145.164 1.00 27.73  ? 134 LEU B CD1 1 
ATOM   3776  C CD2 . LEU B 1 134 ? 101.897 125.492 146.428 1.00 27.73  ? 134 LEU B CD2 1 
ATOM   3777  N N   . THR B 1 135 ? 104.243 123.242 142.238 1.00 27.41  ? 135 THR B N   1 
ATOM   3778  C CA  . THR B 1 135 ? 104.418 122.557 140.962 1.00 27.41  ? 135 THR B CA  1 
ATOM   3779  C C   . THR B 1 135 ? 103.330 121.496 140.805 1.00 27.41  ? 135 THR B C   1 
ATOM   3780  O O   . THR B 1 135 ? 103.583 120.293 140.773 1.00 27.41  ? 135 THR B O   1 
ATOM   3781  C CB  . THR B 1 135 ? 105.813 121.950 140.873 1.00 27.41  ? 135 THR B CB  1 
ATOM   3782  O OG1 . THR B 1 135 ? 106.755 122.830 141.497 1.00 27.41  ? 135 THR B OG1 1 
ATOM   3783  C CG2 . THR B 1 135 ? 106.209 121.746 139.422 1.00 27.41  ? 135 THR B CG2 1 
ATOM   3784  N N   . LEU B 1 136 ? 102.093 121.978 140.715 1.00 31.17  ? 136 LEU B N   1 
ATOM   3785  C CA  . LEU B 1 136 ? 100.953 121.082 140.572 1.00 31.17  ? 136 LEU B CA  1 
ATOM   3786  C C   . LEU B 1 136 ? 101.045 120.304 139.267 1.00 31.17  ? 136 LEU B C   1 
ATOM   3787  O O   . LEU B 1 136 ? 101.523 120.814 138.251 1.00 31.17  ? 136 LEU B O   1 
ATOM   3788  C CB  . LEU B 1 136 ? 99.648  121.874 140.614 1.00 31.17  ? 136 LEU B CB  1 
ATOM   3789  C CG  . LEU B 1 136 ? 99.530  122.952 141.687 1.00 31.17  ? 136 LEU B CG  1 
ATOM   3790  C CD1 . LEU B 1 136 ? 98.362  123.859 141.380 1.00 31.17  ? 136 LEU B CD1 1 
ATOM   3791  C CD2 . LEU B 1 136 ? 99.364  122.325 143.052 1.00 31.17  ? 136 LEU B CD2 1 
ATOM   3792  N N   . SER B 1 137 ? 100.584 119.058 139.298 1.00 36.14  ? 137 SER B N   1 
ATOM   3793  C CA  . SER B 1 137 ? 100.614 118.178 138.139 1.00 36.14  ? 137 SER B CA  1 
ATOM   3794  C C   . SER B 1 137 ? 99.195  117.931 137.652 1.00 36.14  ? 137 SER B C   1 
ATOM   3795  O O   . SER B 1 137 ? 98.312  117.593 138.446 1.00 36.14  ? 137 SER B O   1 
ATOM   3796  C CB  . SER B 1 137 ? 101.290 116.849 138.478 1.00 36.14  ? 137 SER B CB  1 
ATOM   3797  O OG  . SER B 1 137 ? 100.439 116.035 139.263 1.00 36.14  ? 137 SER B OG  1 
ATOM   3798  N N   . CYS B 1 138 ? 98.980  118.101 136.349 1.00 47.38  ? 138 CYS B N   1 
ATOM   3799  C CA  . CYS B 1 138 ? 97.683  117.843 135.732 1.00 47.38  ? 138 CYS B CA  1 
ATOM   3800  C C   . CYS B 1 138 ? 97.896  116.922 134.539 1.00 47.38  ? 138 CYS B C   1 
ATOM   3801  O O   . CYS B 1 138 ? 98.669  117.268 133.623 1.00 47.38  ? 138 CYS B O   1 
ATOM   3802  C CB  . CYS B 1 138 ? 96.999  119.142 135.299 1.00 47.38  ? 138 CYS B CB  1 
ATOM   3803  S SG  . CYS B 1 138 ? 98.024  120.260 134.316 1.00 47.38  ? 138 CYS B SG  1 
ATOM   3804  N N   . PRO B 1 139 ? 97.259  115.754 134.503 1.00 51.24  ? 139 PRO B N   1 
ATOM   3805  C CA  . PRO B 1 139 ? 97.354  114.906 133.311 1.00 51.24  ? 139 PRO B CA  1 
ATOM   3806  C C   . PRO B 1 139 ? 96.752  115.606 132.103 1.00 51.24  ? 139 PRO B C   1 
ATOM   3807  O O   . PRO B 1 139 ? 95.765  116.337 132.213 1.00 51.24  ? 139 PRO B O   1 
ATOM   3808  C CB  . PRO B 1 139 ? 96.557  113.656 133.700 1.00 51.24  ? 139 PRO B CB  1 
ATOM   3809  C CG  . PRO B 1 139 ? 95.632  114.119 134.776 1.00 51.24  ? 139 PRO B CG  1 
ATOM   3810  C CD  . PRO B 1 139 ? 96.382  115.172 135.531 1.00 51.24  ? 139 PRO B CD  1 
ATOM   3811  N N   . MET B 1 140 ? 97.355  115.378 130.942 1.00 52.87  ? 140 MET B N   1 
ATOM   3812  C CA  . MET B 1 140 ? 96.972  116.060 129.716 1.00 52.87  ? 140 MET B CA  1 
ATOM   3813  C C   . MET B 1 140 ? 96.393  115.069 128.717 1.00 52.87  ? 140 MET B C   1 
ATOM   3814  O O   . MET B 1 140 ? 96.883  113.943 128.587 1.00 52.87  ? 140 MET B O   1 
ATOM   3815  C CB  . MET B 1 140 ? 98.171  116.779 129.092 1.00 52.87  ? 140 MET B CB  1 
ATOM   3816  C CG  . MET B 1 140 ? 98.797  117.836 129.983 1.00 52.87  ? 140 MET B CG  1 
ATOM   3817  S SD  . MET B 1 140 ? 98.339  119.515 129.523 1.00 52.87  ? 140 MET B SD  1 
ATOM   3818  C CE  . MET B 1 140 ? 99.154  120.447 130.816 1.00 52.87  ? 140 MET B CE  1 
ATOM   3819  N N   . ASP B 1 141 ? 95.346  115.496 128.018 1.00 51.77  ? 141 ASP B N   1 
ATOM   3820  C CA  . ASP B 1 141 ? 94.770  114.739 126.915 1.00 51.77  ? 141 ASP B CA  1 
ATOM   3821  C C   . ASP B 1 141 ? 95.169  115.422 125.615 1.00 51.77  ? 141 ASP B C   1 
ATOM   3822  O O   . ASP B 1 141 ? 94.764  116.561 125.358 1.00 51.77  ? 141 ASP B O   1 
ATOM   3823  C CB  . ASP B 1 141 ? 93.249  114.655 127.045 1.00 51.77  ? 141 ASP B CB  1 
ATOM   3824  C CG  . ASP B 1 141 ? 92.638  113.604 126.134 1.00 51.77  ? 141 ASP B CG  1 
ATOM   3825  O OD1 . ASP B 1 141 ? 93.152  113.401 125.014 1.00 51.77  ? 141 ASP B OD1 1 
ATOM   3826  O OD2 . ASP B 1 141 ? 91.638  112.978 126.541 1.00 51.77  ? 141 ASP B OD2 1 
ATOM   3827  N N   . LEU B 1 142 ? 95.956  114.729 124.798 1.00 47.81  ? 142 LEU B N   1 
ATOM   3828  C CA  . LEU B 1 142 ? 96.514  115.290 123.574 1.00 47.81  ? 142 LEU B CA  1 
ATOM   3829  C C   . LEU B 1 142 ? 95.943  114.613 122.332 1.00 47.81  ? 142 LEU B C   1 
ATOM   3830  O O   . LEU B 1 142 ? 96.664  114.334 121.373 1.00 47.81  ? 142 LEU B O   1 
ATOM   3831  C CB  . LEU B 1 142 ? 98.036  115.187 123.581 1.00 47.81  ? 142 LEU B CB  1 
ATOM   3832  C CG  . LEU B 1 142 ? 98.735  115.770 124.807 1.00 47.81  ? 142 LEU B CG  1 
ATOM   3833  C CD1 . LEU B 1 142 ? 100.239 115.604 124.696 1.00 47.81  ? 142 LEU B CD1 1 
ATOM   3834  C CD2 . LEU B 1 142 ? 98.366  117.229 124.975 1.00 47.81  ? 142 LEU B CD2 1 
ATOM   3835  N N   . LYS B 1 143 ? 94.637  114.337 122.339 1.00 46.65  ? 143 LYS B N   1 
ATOM   3836  C CA  . LYS B 1 143 ? 94.007  113.753 121.160 1.00 46.65  ? 143 LYS B CA  1 
ATOM   3837  C C   . LYS B 1 143 ? 94.125  114.685 119.962 1.00 46.65  ? 143 LYS B C   1 
ATOM   3838  O O   . LYS B 1 143 ? 94.414  114.240 118.846 1.00 46.65  ? 143 LYS B O   1 
ATOM   3839  C CB  . LYS B 1 143 ? 92.543  113.429 121.453 1.00 46.65  ? 143 LYS B CB  1 
ATOM   3840  N N   . ASN B 1 144 ? 93.909  115.981 120.175 1.00 44.67  ? 144 ASN B N   1 
ATOM   3841  C CA  . ASN B 1 144 ? 94.113  117.011 119.158 1.00 44.67  ? 144 ASN B CA  1 
ATOM   3842  C C   . ASN B 1 144 ? 95.140  117.990 119.714 1.00 44.67  ? 144 ASN B C   1 
ATOM   3843  O O   . ASN B 1 144 ? 94.788  119.024 120.283 1.00 44.67  ? 144 ASN B O   1 
ATOM   3844  C CB  . ASN B 1 144 ? 92.807  117.693 118.812 1.00 44.67  ? 144 ASN B CB  1 
ATOM   3845  C CG  . ASN B 1 144 ? 91.901  117.852 120.010 1.00 44.67  ? 144 ASN B CG  1 
ATOM   3846  O OD1 . ASN B 1 144 ? 91.887  117.009 120.905 1.00 44.67  ? 144 ASN B OD1 1 
ATOM   3847  N ND2 . ASN B 1 144 ? 91.136  118.934 120.035 1.00 44.67  ? 144 ASN B ND2 1 
ATOM   3848  N N   . PHE B 1 145 ? 96.417  117.663 119.528 1.00 46.66  ? 145 PHE B N   1 
ATOM   3849  C CA  . PHE B 1 145 ? 97.478  118.370 120.245 1.00 46.66  ? 145 PHE B CA  1 
ATOM   3850  C C   . PHE B 1 145 ? 97.600  119.845 119.879 1.00 46.66  ? 145 PHE B C   1 
ATOM   3851  O O   . PHE B 1 145 ? 97.617  120.680 120.800 1.00 46.66  ? 145 PHE B O   1 
ATOM   3852  C CB  . PHE B 1 145 ? 98.810  117.644 120.040 1.00 46.66  ? 145 PHE B CB  1 
ATOM   3853  C CG  . PHE B 1 145 ? 100.005 118.490 120.348 1.00 46.66  ? 145 PHE B CG  1 
ATOM   3854  C CD1 . PHE B 1 145 ? 100.253 118.912 121.641 1.00 46.66  ? 145 PHE B CD1 1 
ATOM   3855  C CD2 . PHE B 1 145 ? 100.868 118.882 119.344 1.00 46.66  ? 145 PHE B CD2 1 
ATOM   3856  C CE1 . PHE B 1 145 ? 101.348 119.695 121.930 1.00 46.66  ? 145 PHE B CE1 1 
ATOM   3857  C CE2 . PHE B 1 145 ? 101.965 119.666 119.628 1.00 46.66  ? 145 PHE B CE2 1 
ATOM   3858  C CZ  . PHE B 1 145 ? 102.205 120.074 120.921 1.00 46.66  ? 145 PHE B CZ  1 
ATOM   3859  N N   . PRO B 1 146 ? 97.714  120.243 118.607 1.00 47.39  ? 146 PRO B N   1 
ATOM   3860  C CA  . PRO B 1 146 ? 97.946  121.669 118.323 1.00 47.39  ? 146 PRO B CA  1 
ATOM   3861  C C   . PRO B 1 146 ? 96.839  122.581 118.810 1.00 47.39  ? 146 PRO B C   1 
ATOM   3862  O O   . PRO B 1 146 ? 97.107  123.743 119.136 1.00 47.39  ? 146 PRO B O   1 
ATOM   3863  C CB  . PRO B 1 146 ? 98.066  121.707 116.795 1.00 47.39  ? 146 PRO B CB  1 
ATOM   3864  C CG  . PRO B 1 146 ? 98.491  120.351 116.420 1.00 47.39  ? 146 PRO B CG  1 
ATOM   3865  C CD  . PRO B 1 146 ? 97.796  119.435 117.378 1.00 47.39  ? 146 PRO B CD  1 
ATOM   3866  N N   . MET B 1 147 ? 95.606  122.098 118.871 1.00 49.12  ? 147 MET B N   1 
ATOM   3867  C CA  . MET B 1 147 ? 94.447  122.914 119.213 1.00 49.12  ? 147 MET B CA  1 
ATOM   3868  C C   . MET B 1 147 ? 93.617  122.236 120.293 1.00 49.12  ? 147 MET B C   1 
ATOM   3869  O O   . MET B 1 147 ? 92.400  122.080 120.177 1.00 49.12  ? 147 MET B O   1 
ATOM   3870  C CB  . MET B 1 147 ? 93.643  123.204 117.952 1.00 49.12  ? 147 MET B CB  1 
ATOM   3871  C CG  . MET B 1 147 ? 93.804  122.130 116.886 1.00 49.12  ? 147 MET B CG  1 
ATOM   3872  S SD  . MET B 1 147 ? 93.339  122.668 115.230 1.00 49.12  ? 147 MET B SD  1 
ATOM   3873  C CE  . MET B 1 147 ? 91.560  122.655 115.347 1.00 49.12  ? 147 MET B CE  1 
ATOM   3874  N N   . ASP B 1 148 ? 94.285  121.817 121.364 1.00 43.12  ? 148 ASP B N   1 
ATOM   3875  C CA  . ASP B 1 148 ? 93.651  121.164 122.499 1.00 43.12  ? 148 ASP B CA  1 
ATOM   3876  C C   . ASP B 1 148 ? 93.126  122.191 123.494 1.00 43.12  ? 148 ASP B C   1 
ATOM   3877  O O   . ASP B 1 148 ? 93.467  123.374 123.445 1.00 43.12  ? 148 ASP B O   1 
ATOM   3878  C CB  . ASP B 1 148 ? 94.637  120.230 123.199 1.00 43.12  ? 148 ASP B CB  1 
ATOM   3879  C CG  . ASP B 1 148 ? 95.947  120.916 123.531 1.00 43.12  ? 148 ASP B CG  1 
ATOM   3880  O OD1 . ASP B 1 148 ? 96.141  122.069 123.096 1.00 43.12  ? 148 ASP B OD1 1 
ATOM   3881  O OD2 . ASP B 1 148 ? 96.789  120.302 124.218 1.00 43.12  ? 148 ASP B OD2 1 
ATOM   3882  N N   . VAL B 1 149 ? 92.279  121.719 124.405 1.00 46.59  ? 149 VAL B N   1 
ATOM   3883  C CA  . VAL B 1 149 ? 91.800  122.511 125.532 1.00 46.59  ? 149 VAL B CA  1 
ATOM   3884  C C   . VAL B 1 149 ? 92.144  121.754 126.806 1.00 46.59  ? 149 VAL B C   1 
ATOM   3885  O O   . VAL B 1 149 ? 91.612  120.664 127.049 1.00 46.59  ? 149 VAL B O   1 
ATOM   3886  C CB  . VAL B 1 149 ? 90.291  122.781 125.448 1.00 46.59  ? 149 VAL B CB  1 
ATOM   3887  C CG1 . VAL B 1 149 ? 89.847  123.636 126.619 1.00 46.59  ? 149 VAL B CG1 1 
ATOM   3888  C CG2 . VAL B 1 149 ? 89.949  123.456 124.134 1.00 46.59  ? 149 VAL B CG2 1 
ATOM   3889  N N   . GLN B 1 150 ? 93.016  122.335 127.622 1.00 43.88  ? 150 GLN B N   1 
ATOM   3890  C CA  . GLN B 1 150 ? 93.534  121.678 128.813 1.00 43.88  ? 150 GLN B CA  1 
ATOM   3891  C C   . GLN B 1 150 ? 92.822  122.198 130.053 1.00 43.88  ? 150 GLN B C   1 
ATOM   3892  O O   . GLN B 1 150 ? 92.632  123.409 130.204 1.00 43.88  ? 150 GLN B O   1 
ATOM   3893  C CB  . GLN B 1 150 ? 95.039  121.903 128.943 1.00 43.88  ? 150 GLN B CB  1 
ATOM   3894  C CG  . GLN B 1 150 ? 95.823  121.447 127.738 1.00 43.88  ? 150 GLN B CG  1 
ATOM   3895  C CD  . GLN B 1 150 ? 95.606  119.982 127.447 1.00 43.88  ? 150 GLN B CD  1 
ATOM   3896  O OE1 . GLN B 1 150 ? 95.217  119.608 126.344 1.00 43.88  ? 150 GLN B OE1 1 
ATOM   3897  N NE2 . GLN B 1 150 ? 95.853  119.141 128.442 1.00 43.88  ? 150 GLN B NE2 1 
ATOM   3898  N N   . THR B 1 151 ? 92.432  121.282 130.933 1.00 38.95  ? 151 THR B N   1 
ATOM   3899  C CA  . THR B 1 151 ? 91.861  121.620 132.232 1.00 38.95  ? 151 THR B CA  1 
ATOM   3900  C C   . THR B 1 151 ? 92.779  121.050 133.302 1.00 38.95  ? 151 THR B C   1 
ATOM   3901  O O   . THR B 1 151 ? 92.847  119.830 133.481 1.00 38.95  ? 151 THR B O   1 
ATOM   3902  C CB  . THR B 1 151 ? 90.446  121.067 132.382 1.00 38.95  ? 151 THR B CB  1 
ATOM   3903  O OG1 . THR B 1 151 ? 90.474  119.641 132.251 1.00 38.95  ? 151 THR B OG1 1 
ATOM   3904  C CG2 . THR B 1 151 ? 89.533  121.649 131.320 1.00 38.95  ? 151 THR B CG2 1 
ATOM   3905  N N   . CYS B 1 152 ? 93.487  121.926 134.006 1.00 38.13  ? 152 CYS B N   1 
ATOM   3906  C CA  . CYS B 1 152 ? 94.387  121.517 135.072 1.00 38.13  ? 152 CYS B CA  1 
ATOM   3907  C C   . CYS B 1 152 ? 93.760  121.830 136.423 1.00 38.13  ? 152 CYS B C   1 
ATOM   3908  O O   . CYS B 1 152 ? 93.118  122.869 136.597 1.00 38.13  ? 152 CYS B O   1 
ATOM   3909  C CB  . CYS B 1 152 ? 95.745  122.204 134.936 1.00 38.13  ? 152 CYS B CB  1 
ATOM   3910  S SG  . CYS B 1 152 ? 96.720  121.608 133.529 1.00 38.13  ? 152 CYS B SG  1 
ATOM   3911  N N   . ILE B 1 153 ? 93.951  120.923 137.377 1.00 31.66  ? 153 ILE B N   1 
ATOM   3912  C CA  . ILE B 1 153 ? 93.193  120.904 138.621 1.00 31.66  ? 153 ILE B CA  1 
ATOM   3913  C C   . ILE B 1 153 ? 94.120  121.229 139.781 1.00 31.66  ? 153 ILE B C   1 
ATOM   3914  O O   . ILE B 1 153 ? 95.199  120.639 139.908 1.00 31.66  ? 153 ILE B O   1 
ATOM   3915  C CB  . ILE B 1 153 ? 92.519  119.541 138.838 1.00 31.66  ? 153 ILE B CB  1 
ATOM   3916  C CG1 . ILE B 1 153 ? 91.964  119.004 137.520 1.00 31.66  ? 153 ILE B CG1 1 
ATOM   3917  C CG2 . ILE B 1 153 ? 91.423  119.653 139.872 1.00 31.66  ? 153 ILE B CG2 1 
ATOM   3918  C CD1 . ILE B 1 153 ? 91.482  117.576 137.602 1.00 31.66  ? 153 ILE B CD1 1 
ATOM   3919  N N   . MET B 1 154 ? 93.696  122.162 140.628 1.00 32.26  ? 154 MET B N   1 
ATOM   3920  C CA  . MET B 1 154 ? 94.332  122.422 141.913 1.00 32.26  ? 154 MET B CA  1 
ATOM   3921  C C   . MET B 1 154 ? 93.403  121.921 143.008 1.00 32.26  ? 154 MET B C   1 
ATOM   3922  O O   . MET B 1 154 ? 92.256  122.370 143.102 1.00 32.26  ? 154 MET B O   1 
ATOM   3923  C CB  . MET B 1 154 ? 94.624  123.910 142.099 1.00 32.26  ? 154 MET B CB  1 
ATOM   3924  C CG  . MET B 1 154 ? 95.314  124.231 143.412 1.00 32.26  ? 154 MET B CG  1 
ATOM   3925  S SD  . MET B 1 154 ? 95.784  125.962 143.592 1.00 32.26  ? 154 MET B SD  1 
ATOM   3926  C CE  . MET B 1 154 ? 95.847  126.489 141.885 1.00 32.26  ? 154 MET B CE  1 
ATOM   3927  N N   . GLN B 1 155 ? 93.892  120.998 143.829 1.00 30.71  ? 155 GLN B N   1 
ATOM   3928  C CA  . GLN B 1 155 ? 93.090  120.375 144.872 1.00 30.71  ? 155 GLN B CA  1 
ATOM   3929  C C   . GLN B 1 155 ? 93.611  120.793 146.238 1.00 30.71  ? 155 GLN B C   1 
ATOM   3930  O O   . GLN B 1 155 ? 94.791  120.599 146.542 1.00 30.71  ? 155 GLN B O   1 
ATOM   3931  C CB  . GLN B 1 155 ? 93.114  118.851 144.744 1.00 30.71  ? 155 GLN B CB  1 
ATOM   3932  C CG  . GLN B 1 155 ? 92.429  118.322 143.498 1.00 30.71  ? 155 GLN B CG  1 
ATOM   3933  C CD  . GLN B 1 155 ? 91.968  116.887 143.647 1.00 30.71  ? 155 GLN B CD  1 
ATOM   3934  O OE1 . GLN B 1 155 ? 92.509  115.980 143.016 1.00 30.71  ? 155 GLN B OE1 1 
ATOM   3935  N NE2 . GLN B 1 155 ? 90.962  116.674 144.483 1.00 30.71  ? 155 GLN B NE2 1 
ATOM   3936  N N   . LEU B 1 156 ? 92.730  121.357 147.056 1.00 29.48  ? 156 LEU B N   1 
ATOM   3937  C CA  . LEU B 1 156 ? 93.043  121.728 148.428 1.00 29.48  ? 156 LEU B CA  1 
ATOM   3938  C C   . LEU B 1 156 ? 92.304  120.788 149.368 1.00 29.48  ? 156 LEU B C   1 
ATOM   3939  O O   . LEU B 1 156 ? 91.092  120.599 149.230 1.00 29.48  ? 156 LEU B O   1 
ATOM   3940  C CB  . LEU B 1 156 ? 92.646  123.176 148.714 1.00 29.48  ? 156 LEU B CB  1 
ATOM   3941  C CG  . LEU B 1 156 ? 93.624  124.274 148.302 1.00 29.48  ? 156 LEU B CG  1 
ATOM   3942  C CD1 . LEU B 1 156 ? 93.536  124.545 146.816 1.00 29.48  ? 156 LEU B CD1 1 
ATOM   3943  C CD2 . LEU B 1 156 ? 93.353  125.538 149.090 1.00 29.48  ? 156 LEU B CD2 1 
ATOM   3944  N N   . GLU B 1 157 ? 93.028  120.199 150.314 1.00 34.31  ? 157 GLU B N   1 
ATOM   3945  C CA  . GLU B 1 157 ? 92.407  119.270 151.245 1.00 34.31  ? 157 GLU B CA  1 
ATOM   3946  C C   . GLU B 1 157 ? 93.278  119.150 152.484 1.00 34.31  ? 157 GLU B C   1 
ATOM   3947  O O   . GLU B 1 157 ? 94.462  119.494 152.467 1.00 34.31  ? 157 GLU B O   1 
ATOM   3948  C CB  . GLU B 1 157 ? 92.190  117.899 150.601 1.00 34.31  ? 157 GLU B CB  1 
ATOM   3949  C CG  . GLU B 1 157 ? 93.433  117.045 150.534 1.00 34.31  ? 157 GLU B CG  1 
ATOM   3950  C CD  . GLU B 1 157 ? 93.307  115.928 149.522 1.00 34.31  ? 157 GLU B CD  1 
ATOM   3951  O OE1 . GLU B 1 157 ? 92.500  116.072 148.582 1.00 34.31  ? 157 GLU B OE1 1 
ATOM   3952  O OE2 . GLU B 1 157 ? 94.012  114.907 149.666 1.00 34.31  ? 157 GLU B OE2 1 
ATOM   3953  N N   . SER B 1 158 ? 92.675  118.658 153.560 1.00 33.37  ? 158 SER B N   1 
ATOM   3954  C CA  . SER B 1 158 ? 93.361  118.481 154.830 1.00 33.37  ? 158 SER B CA  1 
ATOM   3955  C C   . SER B 1 158 ? 93.883  117.057 154.960 1.00 33.37  ? 158 SER B C   1 
ATOM   3956  O O   . SER B 1 158 ? 93.455  116.145 154.250 1.00 33.37  ? 158 SER B O   1 
ATOM   3957  C CB  . SER B 1 158 ? 92.431  118.802 156.000 1.00 33.37  ? 158 SER B CB  1 
ATOM   3958  O OG  . SER B 1 158 ? 91.554  117.723 156.256 1.00 33.37  ? 158 SER B OG  1 
ATOM   3959  N N   . PHE B 1 159 ? 94.821  116.877 155.886 1.00 32.42  ? 159 PHE B N   1 
ATOM   3960  C CA  . PHE B 1 159 ? 95.457  115.585 156.103 1.00 32.42  ? 159 PHE B CA  1 
ATOM   3961  C C   . PHE B 1 159 ? 95.192  115.020 157.488 1.00 32.42  ? 159 PHE B C   1 
ATOM   3962  O O   . PHE B 1 159 ? 94.742  113.875 157.608 1.00 32.42  ? 159 PHE B O   1 
ATOM   3963  C CB  . PHE B 1 159 ? 96.969  115.700 155.875 1.00 32.42  ? 159 PHE B CB  1 
ATOM   3964  C CG  . PHE B 1 159 ? 97.650  114.383 155.660 1.00 32.42  ? 159 PHE B CG  1 
ATOM   3965  C CD1 . PHE B 1 159 ? 96.934  113.278 155.241 1.00 32.42  ? 159 PHE B CD1 1 
ATOM   3966  C CD2 . PHE B 1 159 ? 99.007  114.251 155.876 1.00 32.42  ? 159 PHE B CD2 1 
ATOM   3967  C CE1 . PHE B 1 159 ? 97.561  112.069 155.043 1.00 32.42  ? 159 PHE B CE1 1 
ATOM   3968  C CE2 . PHE B 1 159 ? 99.637  113.045 155.678 1.00 32.42  ? 159 PHE B CE2 1 
ATOM   3969  C CZ  . PHE B 1 159 ? 98.913  111.952 155.260 1.00 32.42  ? 159 PHE B CZ  1 
ATOM   3970  N N   . GLY B 1 160 ? 95.462  115.784 158.538 1.00 30.92  ? 160 GLY B N   1 
ATOM   3971  C CA  . GLY B 1 160 ? 95.374  115.272 159.886 1.00 30.92  ? 160 GLY B CA  1 
ATOM   3972  C C   . GLY B 1 160 ? 94.035  115.392 160.567 1.00 30.92  ? 160 GLY B C   1 
ATOM   3973  O O   . GLY B 1 160 ? 93.921  115.029 161.740 1.00 30.92  ? 160 GLY B O   1 
ATOM   3974  N N   . TYR B 1 161 ? 93.008  115.884 159.882 1.00 33.45  ? 161 TYR B N   1 
ATOM   3975  C CA  . TYR B 1 161 ? 91.709  116.096 160.500 1.00 33.45  ? 161 TYR B CA  1 
ATOM   3976  C C   . TYR B 1 161 ? 90.612  115.470 159.654 1.00 33.45  ? 161 TYR B C   1 
ATOM   3977  O O   . TYR B 1 161 ? 90.583  115.635 158.432 1.00 33.45  ? 161 TYR B O   1 
ATOM   3978  C CB  . TYR B 1 161 ? 91.432  117.586 160.696 1.00 33.45  ? 161 TYR B CB  1 
ATOM   3979  C CG  . TYR B 1 161 ? 92.276  118.221 161.773 1.00 33.45  ? 161 TYR B CG  1 
ATOM   3980  C CD1 . TYR B 1 161 ? 92.072  117.918 163.111 1.00 33.45  ? 161 TYR B CD1 1 
ATOM   3981  C CD2 . TYR B 1 161 ? 93.277  119.126 161.453 1.00 33.45  ? 161 TYR B CD2 1 
ATOM   3982  C CE1 . TYR B 1 161 ? 92.841  118.498 164.099 1.00 33.45  ? 161 TYR B CE1 1 
ATOM   3983  C CE2 . TYR B 1 161 ? 94.050  119.711 162.433 1.00 33.45  ? 161 TYR B CE2 1 
ATOM   3984  C CZ  . TYR B 1 161 ? 93.828  119.394 163.753 1.00 33.45  ? 161 TYR B CZ  1 
ATOM   3985  O OH  . TYR B 1 161 ? 94.599  119.976 164.731 1.00 33.45  ? 161 TYR B OH  1 
ATOM   3986  N N   . THR B 1 162 ? 89.710  114.756 160.319 1.00 36.62  ? 162 THR B N   1 
ATOM   3987  C CA  . THR B 1 162 ? 88.567  114.141 159.670 1.00 36.62  ? 162 THR B CA  1 
ATOM   3988  C C   . THR B 1 162 ? 87.523  115.205 159.335 1.00 36.62  ? 162 THR B C   1 
ATOM   3989  O O   . THR B 1 162 ? 87.590  116.345 159.798 1.00 36.62  ? 162 THR B O   1 
ATOM   3990  C CB  . THR B 1 162 ? 87.972  113.059 160.571 1.00 36.62  ? 162 THR B CB  1 
ATOM   3991  O OG1 . THR B 1 162 ? 89.031  112.375 161.251 1.00 36.62  ? 162 THR B OG1 1 
ATOM   3992  C CG2 . THR B 1 162 ? 87.187  112.040 159.760 1.00 36.62  ? 162 THR B CG2 1 
ATOM   3993  N N   . MET B 1 163 ? 86.548  114.822 158.507 1.00 40.45  ? 163 MET B N   1 
ATOM   3994  C CA  . MET B 1 163 ? 85.471  115.740 158.154 1.00 40.45  ? 163 MET B CA  1 
ATOM   3995  C C   . MET B 1 163 ? 84.698  116.195 159.385 1.00 40.45  ? 163 MET B C   1 
ATOM   3996  O O   . MET B 1 163 ? 84.130  117.293 159.392 1.00 40.45  ? 163 MET B O   1 
ATOM   3997  C CB  . MET B 1 163 ? 84.534  115.078 157.143 1.00 40.45  ? 163 MET B CB  1 
ATOM   3998  C CG  . MET B 1 163 ? 83.303  115.890 156.791 1.00 40.45  ? 163 MET B CG  1 
ATOM   3999  S SD  . MET B 1 163 ? 83.690  117.313 155.761 1.00 40.45  ? 163 MET B SD  1 
ATOM   4000  C CE  . MET B 1 163 ? 83.882  116.526 154.166 1.00 40.45  ? 163 MET B CE  1 
ATOM   4001  N N   . ASN B 1 164 ? 84.682  115.381 160.441 1.00 44.63  ? 164 ASN B N   1 
ATOM   4002  C CA  . ASN B 1 164 ? 84.002  115.760 161.672 1.00 44.63  ? 164 ASN B CA  1 
ATOM   4003  C C   . ASN B 1 164 ? 84.686  116.909 162.399 1.00 44.63  ? 164 ASN B C   1 
ATOM   4004  O O   . ASN B 1 164 ? 84.097  117.458 163.336 1.00 44.63  ? 164 ASN B O   1 
ATOM   4005  C CB  . ASN B 1 164 ? 83.903  114.557 162.611 1.00 44.63  ? 164 ASN B CB  1 
ATOM   4006  C CG  . ASN B 1 164 ? 82.908  113.523 162.130 1.00 44.63  ? 164 ASN B CG  1 
ATOM   4007  O OD1 . ASN B 1 164 ? 83.267  112.376 161.862 1.00 44.63  ? 164 ASN B OD1 1 
ATOM   4008  N ND2 . ASN B 1 164 ? 81.647  113.922 162.021 1.00 44.63  ? 164 ASN B ND2 1 
ATOM   4009  N N   . ASP B 1 165 ? 85.900  117.282 162.004 1.00 41.68  ? 165 ASP B N   1 
ATOM   4010  C CA  . ASP B 1 165 ? 86.673  118.301 162.705 1.00 41.68  ? 165 ASP B CA  1 
ATOM   4011  C C   . ASP B 1 165 ? 86.925  119.555 161.886 1.00 41.68  ? 165 ASP B C   1 
ATOM   4012  O O   . ASP B 1 165 ? 86.777  120.661 162.406 1.00 41.68  ? 165 ASP B O   1 
ATOM   4013  C CB  . ASP B 1 165 ? 88.019  117.723 163.154 1.00 41.68  ? 165 ASP B CB  1 
ATOM   4014  C CG  . ASP B 1 165 ? 87.867  116.634 164.195 1.00 41.68  ? 165 ASP B CG  1 
ATOM   4015  O OD1 . ASP B 1 165 ? 86.730  116.409 164.658 1.00 41.68  ? 165 ASP B OD1 1 
ATOM   4016  O OD2 . ASP B 1 165 ? 88.884  116.003 164.551 1.00 41.68  ? 165 ASP B OD2 1 
ATOM   4017  N N   . LEU B 1 166 ? 87.311  119.420 160.621 1.00 32.52  ? 166 LEU B N   1 
ATOM   4018  C CA  . LEU B 1 166 ? 87.692  120.556 159.795 1.00 32.52  ? 166 LEU B CA  1 
ATOM   4019  C C   . LEU B 1 166 ? 86.947  120.483 158.472 1.00 32.52  ? 166 LEU B C   1 
ATOM   4020  O O   . LEU B 1 166 ? 86.933  119.434 157.823 1.00 32.52  ? 166 LEU B O   1 
ATOM   4021  C CB  . LEU B 1 166 ? 89.205  120.568 159.564 1.00 32.52  ? 166 LEU B CB  1 
ATOM   4022  C CG  . LEU B 1 166 ? 89.765  121.477 158.475 1.00 32.52  ? 166 LEU B CG  1 
ATOM   4023  C CD1 . LEU B 1 166 ? 89.410  122.913 158.758 1.00 32.52  ? 166 LEU B CD1 1 
ATOM   4024  C CD2 . LEU B 1 166 ? 91.268  121.316 158.387 1.00 32.52  ? 166 LEU B CD2 1 
ATOM   4025  N N   . ILE B 1 167 ? 86.328  121.594 158.078 1.00 31.76  ? 167 ILE B N   1 
ATOM   4026  C CA  . ILE B 1 167 ? 85.535  121.667 156.856 1.00 31.76  ? 167 ILE B CA  1 
ATOM   4027  C C   . ILE B 1 167 ? 86.033  122.842 156.028 1.00 31.76  ? 167 ILE B C   1 
ATOM   4028  O O   . ILE B 1 167 ? 86.012  123.986 156.495 1.00 31.76  ? 167 ILE B O   1 
ATOM   4029  C CB  . ILE B 1 167 ? 84.034  121.817 157.153 1.00 31.76  ? 167 ILE B CB  1 
ATOM   4030  C CG1 . ILE B 1 167 ? 83.466  120.514 157.714 1.00 31.76  ? 167 ILE B CG1 1 
ATOM   4031  C CG2 . ILE B 1 167 ? 83.282  122.226 155.902 1.00 31.76  ? 167 ILE B CG2 1 
ATOM   4032  C CD1 . ILE B 1 167 ? 81.973  120.548 157.933 1.00 31.76  ? 167 ILE B CD1 1 
ATOM   4033  N N   . PHE B 1 168 ? 86.467  122.564 154.805 1.00 30.21  ? 168 PHE B N   1 
ATOM   4034  C CA  . PHE B 1 168 ? 86.927  123.588 153.881 1.00 30.21  ? 168 PHE B CA  1 
ATOM   4035  C C   . PHE B 1 168 ? 85.801  123.982 152.935 1.00 30.21  ? 168 PHE B C   1 
ATOM   4036  O O   . PHE B 1 168 ? 84.936  123.170 152.600 1.00 30.21  ? 168 PHE B O   1 
ATOM   4037  C CB  . PHE B 1 168 ? 88.123  123.097 153.066 1.00 30.21  ? 168 PHE B CB  1 
ATOM   4038  C CG  . PHE B 1 168 ? 89.422  123.136 153.807 1.00 30.21  ? 168 PHE B CG  1 
ATOM   4039  C CD1 . PHE B 1 168 ? 89.563  123.895 154.950 1.00 30.21  ? 168 PHE B CD1 1 
ATOM   4040  C CD2 . PHE B 1 168 ? 90.507  122.412 153.354 1.00 30.21  ? 168 PHE B CD2 1 
ATOM   4041  C CE1 . PHE B 1 168 ? 90.761  123.928 155.627 1.00 30.21  ? 168 PHE B CE1 1 
ATOM   4042  C CE2 . PHE B 1 168 ? 91.703  122.442 154.026 1.00 30.21  ? 168 PHE B CE2 1 
ATOM   4043  C CZ  . PHE B 1 168 ? 91.830  123.200 155.164 1.00 30.21  ? 168 PHE B CZ  1 
ATOM   4044  N N   . GLU B 1 169 ? 85.823  125.240 152.503 1.00 32.11  ? 169 GLU B N   1 
ATOM   4045  C CA  . GLU B 1 169 ? 84.835  125.730 151.553 1.00 32.11  ? 169 GLU B CA  1 
ATOM   4046  C C   . GLU B 1 169 ? 85.349  127.017 150.927 1.00 32.11  ? 169 GLU B C   1 
ATOM   4047  O O   . GLU B 1 169 ? 86.133  127.748 151.537 1.00 32.11  ? 169 GLU B O   1 
ATOM   4048  C CB  . GLU B 1 169 ? 83.477  125.955 152.226 1.00 32.11  ? 169 GLU B CB  1 
ATOM   4049  C CG  . GLU B 1 169 ? 83.219  127.380 152.655 1.00 32.11  ? 169 GLU B CG  1 
ATOM   4050  C CD  . GLU B 1 169 ? 81.946  127.521 153.458 1.00 32.11  ? 169 GLU B CD  1 
ATOM   4051  O OE1 . GLU B 1 169 ? 81.719  126.690 154.362 1.00 32.11  ? 169 GLU B OE1 1 
ATOM   4052  O OE2 . GLU B 1 169 ? 81.172  128.462 153.188 1.00 32.11  ? 169 GLU B OE2 1 
ATOM   4053  N N   . TRP B 1 170 ? 84.902  127.283 149.703 1.00 32.67  ? 170 TRP B N   1 
ATOM   4054  C CA  . TRP B 1 170 ? 85.318  128.480 148.990 1.00 32.67  ? 170 TRP B CA  1 
ATOM   4055  C C   . TRP B 1 170 ? 84.655  129.713 149.595 1.00 32.67  ? 170 TRP B C   1 
ATOM   4056  O O   . TRP B 1 170 ? 83.889  129.637 150.558 1.00 32.67  ? 170 TRP B O   1 
ATOM   4057  C CB  . TRP B 1 170 ? 84.969  128.373 147.509 1.00 32.67  ? 170 TRP B CB  1 
ATOM   4058  C CG  . TRP B 1 170 ? 85.918  127.559 146.691 1.00 32.67  ? 170 TRP B CG  1 
ATOM   4059  C CD1 . TRP B 1 170 ? 85.603  126.501 145.898 1.00 32.67  ? 170 TRP B CD1 1 
ATOM   4060  C CD2 . TRP B 1 170 ? 87.332  127.749 146.565 1.00 32.67  ? 170 TRP B CD2 1 
ATOM   4061  N NE1 . TRP B 1 170 ? 86.731  126.013 145.290 1.00 32.67  ? 170 TRP B NE1 1 
ATOM   4062  C CE2 . TRP B 1 170 ? 87.806  126.765 145.682 1.00 32.67  ? 170 TRP B CE2 1 
ATOM   4063  C CE3 . TRP B 1 170 ? 88.241  128.654 147.111 1.00 32.67  ? 170 TRP B CE3 1 
ATOM   4064  C CZ2 . TRP B 1 170 ? 89.148  126.654 145.341 1.00 32.67  ? 170 TRP B CZ2 1 
ATOM   4065  C CZ3 . TRP B 1 170 ? 89.573  128.542 146.769 1.00 32.67  ? 170 TRP B CZ3 1 
ATOM   4066  C CH2 . TRP B 1 170 ? 90.014  127.551 145.893 1.00 32.67  ? 170 TRP B CH2 1 
ATOM   4067  N N   . GLN B 1 171 ? 84.946  130.867 149.011 1.00 39.78  ? 171 GLN B N   1 
ATOM   4068  C CA  . GLN B 1 171 ? 84.315  132.114 149.406 1.00 39.78  ? 171 GLN B CA  1 
ATOM   4069  C C   . GLN B 1 171 ? 83.173  132.436 148.451 1.00 39.78  ? 171 GLN B C   1 
ATOM   4070  O O   . GLN B 1 171 ? 83.221  132.101 147.265 1.00 39.78  ? 171 GLN B O   1 
ATOM   4071  C CB  . GLN B 1 171 ? 85.328  133.258 149.423 1.00 39.78  ? 171 GLN B CB  1 
ATOM   4072  C CG  . GLN B 1 171 ? 84.912  134.438 150.275 1.00 39.78  ? 171 GLN B CG  1 
ATOM   4073  C CD  . GLN B 1 171 ? 86.011  135.468 150.410 1.00 39.78  ? 171 GLN B CD  1 
ATOM   4074  O OE1 . GLN B 1 171 ? 87.183  135.176 150.176 1.00 39.78  ? 171 GLN B OE1 1 
ATOM   4075  N NE2 . GLN B 1 171 ? 85.639  136.685 150.786 1.00 39.78  ? 171 GLN B NE2 1 
ATOM   4076  N N   . ASP B 1 172 ? 82.136  133.083 148.985 1.00 46.51  ? 172 ASP B N   1 
ATOM   4077  C CA  . ASP B 1 172 ? 80.945  133.357 148.186 1.00 46.51  ? 172 ASP B CA  1 
ATOM   4078  C C   . ASP B 1 172 ? 81.256  134.282 147.015 1.00 46.51  ? 172 ASP B C   1 
ATOM   4079  O O   . ASP B 1 172 ? 80.794  134.049 145.893 1.00 46.51  ? 172 ASP B O   1 
ATOM   4080  C CB  . ASP B 1 172 ? 79.851  133.956 149.069 1.00 46.51  ? 172 ASP B CB  1 
ATOM   4081  C CG  . ASP B 1 172 ? 80.382  135.017 150.010 1.00 46.51  ? 172 ASP B CG  1 
ATOM   4082  O OD1 . ASP B 1 172 ? 81.596  135.304 149.957 1.00 46.51  ? 172 ASP B OD1 1 
ATOM   4083  O OD2 . ASP B 1 172 ? 79.587  135.562 150.804 1.00 46.51  ? 172 ASP B OD2 1 
ATOM   4084  N N   . GLU B 1 173 ? 82.038  135.331 147.253 1.00 46.76  ? 173 GLU B N   1 
ATOM   4085  C CA  . GLU B 1 173 ? 82.385  136.303 146.227 1.00 46.76  ? 173 GLU B CA  1 
ATOM   4086  C C   . GLU B 1 173 ? 83.889  136.298 145.998 1.00 46.76  ? 173 GLU B C   1 
ATOM   4087  O O   . GLU B 1 173 ? 84.671  136.233 146.952 1.00 46.76  ? 173 GLU B O   1 
ATOM   4088  C CB  . GLU B 1 173 ? 81.890  137.709 146.611 1.00 46.76  ? 173 GLU B CB  1 
ATOM   4089  C CG  . GLU B 1 173 ? 82.412  138.255 147.939 1.00 46.76  ? 173 GLU B CG  1 
ATOM   4090  C CD  . GLU B 1 173 ? 83.783  138.897 147.832 1.00 46.76  ? 173 GLU B CD  1 
ATOM   4091  O OE1 . GLU B 1 173 ? 84.404  139.152 148.885 1.00 46.76  ? 173 GLU B OE1 1 
ATOM   4092  O OE2 . GLU B 1 173 ? 84.236  139.157 146.698 1.00 46.76  ? 173 GLU B OE2 1 
ATOM   4093  N N   . ALA B 1 174 ? 84.283  136.358 144.726 1.00 41.25  ? 174 ALA B N   1 
ATOM   4094  C CA  . ALA B 1 174 ? 85.678  136.321 144.304 1.00 41.25  ? 174 ALA B CA  1 
ATOM   4095  C C   . ALA B 1 174 ? 86.407  135.144 144.941 1.00 41.25  ? 174 ALA B C   1 
ATOM   4096  O O   . ALA B 1 174 ? 87.286  135.344 145.788 1.00 41.25  ? 174 ALA B O   1 
ATOM   4097  C CB  . ALA B 1 174 ? 86.382  137.633 144.654 1.00 41.25  ? 174 ALA B CB  1 
ATOM   4098  N N   . PRO B 1 175 ? 86.072  133.911 144.572 1.00 41.28  ? 175 PRO B N   1 
ATOM   4099  C CA  . PRO B 1 175 ? 86.735  132.754 145.187 1.00 41.28  ? 175 PRO B CA  1 
ATOM   4100  C C   . PRO B 1 175 ? 88.208  132.669 144.826 1.00 41.28  ? 175 PRO B C   1 
ATOM   4101  O O   . PRO B 1 175 ? 89.060  132.543 145.708 1.00 41.28  ? 175 PRO B O   1 
ATOM   4102  C CB  . PRO B 1 175 ? 85.948  131.563 144.629 1.00 41.28  ? 175 PRO B CB  1 
ATOM   4103  C CG  . PRO B 1 175 ? 85.360  132.062 143.358 1.00 41.28  ? 175 PRO B CG  1 
ATOM   4104  C CD  . PRO B 1 175 ? 85.074  133.513 143.566 1.00 41.28  ? 175 PRO B CD  1 
ATOM   4105  N N   . VAL B 1 176 ? 88.520  132.734 143.536 1.00 47.29  ? 176 VAL B N   1 
ATOM   4106  C CA  . VAL B 1 176 ? 89.896  132.763 143.058 1.00 47.29  ? 176 VAL B CA  1 
ATOM   4107  C C   . VAL B 1 176 ? 90.034  133.946 142.112 1.00 47.29  ? 176 VAL B C   1 
ATOM   4108  O O   . VAL B 1 176 ? 89.276  134.063 141.143 1.00 47.29  ? 176 VAL B O   1 
ATOM   4109  C CB  . VAL B 1 176 ? 90.299  131.451 142.366 1.00 47.29  ? 176 VAL B CB  1 
ATOM   4110  C CG1 . VAL B 1 176 ? 89.222  130.999 141.400 1.00 47.29  ? 176 VAL B CG1 1 
ATOM   4111  C CG2 . VAL B 1 176 ? 91.620  131.623 141.645 1.00 47.29  ? 176 VAL B CG2 1 
ATOM   4112  N N   . GLN B 1 177 ? 90.986  134.826 142.399 1.00 37.25  ? 177 GLN B N   1 
ATOM   4113  C CA  . GLN B 1 177 ? 91.161  136.066 141.657 1.00 37.25  ? 177 GLN B CA  1 
ATOM   4114  C C   . GLN B 1 177 ? 92.534  136.079 141.005 1.00 37.25  ? 177 GLN B C   1 
ATOM   4115  O O   . GLN B 1 177 ? 93.542  135.808 141.664 1.00 37.25  ? 177 GLN B O   1 
ATOM   4116  C CB  . GLN B 1 177 ? 90.990  137.276 142.575 1.00 37.25  ? 177 GLN B CB  1 
ATOM   4117  C CG  . GLN B 1 177 ? 91.684  137.137 143.911 1.00 37.25  ? 177 GLN B CG  1 
ATOM   4118  C CD  . GLN B 1 177 ? 90.926  137.819 145.028 1.00 37.25  ? 177 GLN B CD  1 
ATOM   4119  O OE1 . GLN B 1 177 ? 91.432  137.970 146.137 1.00 37.25  ? 177 GLN B OE1 1 
ATOM   4120  N NE2 . GLN B 1 177 ? 89.699  138.231 144.740 1.00 37.25  ? 177 GLN B NE2 1 
ATOM   4121  N N   . VAL B 1 178 ? 92.567  136.393 139.717 1.00 34.24  ? 178 VAL B N   1 
ATOM   4122  C CA  . VAL B 1 178 ? 93.795  136.405 138.934 1.00 34.24  ? 178 VAL B CA  1 
ATOM   4123  C C   . VAL B 1 178 ? 94.350  137.820 138.914 1.00 34.24  ? 178 VAL B C   1 
ATOM   4124  O O   . VAL B 1 178 ? 93.596  138.795 138.816 1.00 34.24  ? 178 VAL B O   1 
ATOM   4125  C CB  . VAL B 1 178 ? 93.543  135.888 137.507 1.00 34.24  ? 178 VAL B CB  1 
ATOM   4126  C CG1 . VAL B 1 178 ? 94.851  135.726 136.764 1.00 34.24  ? 178 VAL B CG1 1 
ATOM   4127  C CG2 . VAL B 1 178 ? 92.789  134.574 137.551 1.00 34.24  ? 178 VAL B CG2 1 
ATOM   4128  N N   . ALA B 1 179 ? 95.672  137.934 139.016 1.00 40.39  ? 179 ALA B N   1 
ATOM   4129  C CA  . ALA B 1 179 ? 96.311  139.240 138.980 1.00 40.39  ? 179 ALA B CA  1 
ATOM   4130  C C   . ALA B 1 179 ? 96.119  139.889 137.616 1.00 40.39  ? 179 ALA B C   1 
ATOM   4131  O O   . ALA B 1 179 ? 96.180  139.224 136.579 1.00 40.39  ? 179 ALA B O   1 
ATOM   4132  C CB  . ALA B 1 179 ? 97.800  139.111 139.297 1.00 40.39  ? 179 ALA B CB  1 
ATOM   4133  N N   . GLU B 1 180 ? 95.881  141.197 137.625 1.00 44.26  ? 180 GLU B N   1 
ATOM   4134  C CA  . GLU B 1 180 ? 95.674  141.928 136.383 1.00 44.26  ? 180 GLU B CA  1 
ATOM   4135  C C   . GLU B 1 180 ? 96.957  141.966 135.563 1.00 44.26  ? 180 GLU B C   1 
ATOM   4136  O O   . GLU B 1 180 ? 98.054  142.140 136.101 1.00 44.26  ? 180 GLU B O   1 
ATOM   4137  C CB  . GLU B 1 180 ? 95.196  143.349 136.677 1.00 44.26  ? 180 GLU B CB  1 
ATOM   4138  N N   . GLY B 1 181 ? 96.813  141.802 134.252 1.00 44.09  ? 181 GLY B N   1 
ATOM   4139  C CA  . GLY B 1 181 ? 97.951  141.840 133.358 1.00 44.09  ? 181 GLY B CA  1 
ATOM   4140  C C   . GLY B 1 181 ? 98.739  140.556 133.259 1.00 44.09  ? 181 GLY B C   1 
ATOM   4141  O O   . GLY B 1 181 ? 99.797  140.549 132.619 1.00 44.09  ? 181 GLY B O   1 
ATOM   4142  N N   . LEU B 1 182 ? 98.268  139.472 133.869 1.00 46.34  ? 182 LEU B N   1 
ATOM   4143  C CA  . LEU B 1 182 ? 98.970  138.200 133.779 1.00 46.34  ? 182 LEU B CA  1 
ATOM   4144  C C   . LEU B 1 182 ? 98.858  137.634 132.370 1.00 46.34  ? 182 LEU B C   1 
ATOM   4145  O O   . LEU B 1 182 ? 97.771  137.602 131.786 1.00 46.34  ? 182 LEU B O   1 
ATOM   4146  C CB  . LEU B 1 182 ? 98.406  137.205 134.790 1.00 46.34  ? 182 LEU B CB  1 
ATOM   4147  C CG  . LEU B 1 182 ? 98.852  135.759 134.582 1.00 46.34  ? 182 LEU B CG  1 
ATOM   4148  C CD1 . LEU B 1 182 ? 100.349 135.636 134.790 1.00 46.34  ? 182 LEU B CD1 1 
ATOM   4149  C CD2 . LEU B 1 182 ? 98.104  134.821 135.505 1.00 46.34  ? 182 LEU B CD2 1 
ATOM   4150  N N   . THR B 1 183 ? 99.984  137.182 131.826 1.00 45.72  ? 183 THR B N   1 
ATOM   4151  C CA  . THR B 1 183 ? 100.025 136.598 130.497 1.00 45.72  ? 183 THR B CA  1 
ATOM   4152  C C   . THR B 1 183 ? 100.772 135.274 130.541 1.00 45.72  ? 183 THR B C   1 
ATOM   4153  O O   . THR B 1 183 ? 101.692 135.086 131.341 1.00 45.72  ? 183 THR B O   1 
ATOM   4154  C CB  . THR B 1 183 ? 100.697 137.532 129.487 1.00 45.72  ? 183 THR B CB  1 
ATOM   4155  O OG1 . THR B 1 183 ? 100.892 136.837 128.250 1.00 45.72  ? 183 THR B OG1 1 
ATOM   4156  C CG2 . THR B 1 183 ? 102.041 138.006 130.015 1.00 45.72  ? 183 THR B CG2 1 
ATOM   4157  N N   . LEU B 1 184 ? 100.363 134.358 129.672 1.00 43.15  ? 184 LEU B N   1 
ATOM   4158  C CA  . LEU B 1 184 ? 101.002 133.061 129.569 1.00 43.15  ? 184 LEU B CA  1 
ATOM   4159  C C   . LEU B 1 184 ? 101.749 132.950 128.247 1.00 43.15  ? 184 LEU B C   1 
ATOM   4160  O O   . LEU B 1 184 ? 101.265 133.444 127.222 1.00 43.15  ? 184 LEU B O   1 
ATOM   4161  C CB  . LEU B 1 184 ? 99.977  131.927 129.672 1.00 43.15  ? 184 LEU B CB  1 
ATOM   4162  C CG  . LEU B 1 184 ? 99.489  131.584 131.080 1.00 43.15  ? 184 LEU B CG  1 
ATOM   4163  C CD1 . LEU B 1 184 ? 98.398  132.539 131.527 1.00 43.15  ? 184 LEU B CD1 1 
ATOM   4164  C CD2 . LEU B 1 184 ? 98.998  130.153 131.136 1.00 43.15  ? 184 LEU B CD2 1 
ATOM   4165  N N   . PRO B 1 185 ? 102.929 132.327 128.241 1.00 43.82  ? 185 PRO B N   1 
ATOM   4166  C CA  . PRO B 1 185 ? 103.722 132.289 127.000 1.00 43.82  ? 185 PRO B CA  1 
ATOM   4167  C C   . PRO B 1 185 ? 103.025 131.592 125.845 1.00 43.82  ? 185 PRO B C   1 
ATOM   4168  O O   . PRO B 1 185 ? 103.153 132.033 124.697 1.00 43.82  ? 185 PRO B O   1 
ATOM   4169  C CB  . PRO B 1 185 ? 104.996 131.547 127.427 1.00 43.82  ? 185 PRO B CB  1 
ATOM   4170  C CG  . PRO B 1 185 ? 104.587 130.747 128.621 1.00 43.82  ? 185 PRO B CG  1 
ATOM   4171  C CD  . PRO B 1 185 ? 103.570 131.581 129.335 1.00 43.82  ? 185 PRO B CD  1 
ATOM   4172  N N   . GLN B 1 186 ? 102.284 130.514 126.112 1.00 44.67  ? 186 GLN B N   1 
ATOM   4173  C CA  . GLN B 1 186 ? 101.677 129.737 125.039 1.00 44.67  ? 186 GLN B CA  1 
ATOM   4174  C C   . GLN B 1 186 ? 100.278 129.252 125.401 1.00 44.67  ? 186 GLN B C   1 
ATOM   4175  O O   . GLN B 1 186 ? 99.865  128.173 124.964 1.00 44.67  ? 186 GLN B O   1 
ATOM   4176  C CB  . GLN B 1 186 ? 102.556 128.543 124.668 1.00 44.67  ? 186 GLN B CB  1 
ATOM   4177  C CG  . GLN B 1 186 ? 103.349 127.981 125.833 1.00 44.67  ? 186 GLN B CG  1 
ATOM   4178  C CD  . GLN B 1 186 ? 104.082 126.704 125.477 1.00 44.67  ? 186 GLN B CD  1 
ATOM   4179  O OE1 . GLN B 1 186 ? 104.083 126.277 124.323 1.00 44.67  ? 186 GLN B OE1 1 
ATOM   4180  N NE2 . GLN B 1 186 ? 104.712 126.086 126.469 1.00 44.67  ? 186 GLN B NE2 1 
ATOM   4181  N N   . PHE B 1 187 ? 99.535  130.022 126.191 1.00 42.26  ? 187 PHE B N   1 
ATOM   4182  C CA  . PHE B 1 187 ? 98.202  129.604 126.603 1.00 42.26  ? 187 PHE B CA  1 
ATOM   4183  C C   . PHE B 1 187 ? 97.352  130.828 126.905 1.00 42.26  ? 187 PHE B C   1 
ATOM   4184  O O   . PHE B 1 187 ? 97.859  131.941 127.063 1.00 42.26  ? 187 PHE B O   1 
ATOM   4185  C CB  . PHE B 1 187 ? 98.252  128.685 127.829 1.00 42.26  ? 187 PHE B CB  1 
ATOM   4186  C CG  . PHE B 1 187 ? 98.594  127.260 127.508 1.00 42.26  ? 187 PHE B CG  1 
ATOM   4187  C CD1 . PHE B 1 187 ? 97.637  126.404 126.999 1.00 42.26  ? 187 PHE B CD1 1 
ATOM   4188  C CD2 . PHE B 1 187 ? 99.871  126.776 127.725 1.00 42.26  ? 187 PHE B CD2 1 
ATOM   4189  C CE1 . PHE B 1 187 ? 97.949  125.093 126.707 1.00 42.26  ? 187 PHE B CE1 1 
ATOM   4190  C CE2 . PHE B 1 187 ? 100.187 125.466 127.434 1.00 42.26  ? 187 PHE B CE2 1 
ATOM   4191  C CZ  . PHE B 1 187 ? 99.225  124.624 126.925 1.00 42.26  ? 187 PHE B CZ  1 
ATOM   4192  N N   . LEU B 1 188 ? 96.042  130.603 126.982 1.00 48.40  ? 188 LEU B N   1 
ATOM   4193  C CA  . LEU B 1 188 ? 95.077  131.629 127.348 1.00 48.40  ? 188 LEU B CA  1 
ATOM   4194  C C   . LEU B 1 188 ? 94.224  131.122 128.500 1.00 48.40  ? 188 LEU B C   1 
ATOM   4195  O O   . LEU B 1 188 ? 93.875  129.939 128.548 1.00 48.40  ? 188 LEU B O   1 
ATOM   4196  C CB  . LEU B 1 188 ? 94.177  132.001 126.168 1.00 48.40  ? 188 LEU B CB  1 
ATOM   4197  C CG  . LEU B 1 188 ? 94.847  132.203 124.811 1.00 48.40  ? 188 LEU B CG  1 
ATOM   4198  C CD1 . LEU B 1 188 ? 93.805  132.506 123.748 1.00 48.40  ? 188 LEU B CD1 1 
ATOM   4199  C CD2 . LEU B 1 188 ? 95.880  133.313 124.884 1.00 48.40  ? 188 LEU B CD2 1 
ATOM   4200  N N   . LEU B 1 189 ? 93.887  132.016 129.424 1.00 48.44  ? 189 LEU B N   1 
ATOM   4201  C CA  . LEU B 1 189 ? 93.051  131.686 130.571 1.00 48.44  ? 189 LEU B CA  1 
ATOM   4202  C C   . LEU B 1 189 ? 91.654  132.247 130.361 1.00 48.44  ? 189 LEU B C   1 
ATOM   4203  O O   . LEU B 1 189 ? 91.493  133.447 130.118 1.00 48.44  ? 189 LEU B O   1 
ATOM   4204  C CB  . LEU B 1 189 ? 93.643  132.242 131.866 1.00 48.44  ? 189 LEU B CB  1 
ATOM   4205  C CG  . LEU B 1 189 ? 94.929  131.600 132.376 1.00 48.44  ? 189 LEU B CG  1 
ATOM   4206  C CD1 . LEU B 1 189 ? 95.235  132.086 133.778 1.00 48.44  ? 189 LEU B CD1 1 
ATOM   4207  C CD2 . LEU B 1 189 ? 94.801  130.096 132.351 1.00 48.44  ? 189 LEU B CD2 1 
ATOM   4208  N N   . LYS B 1 190 ? 90.650  131.383 130.458 1.00 55.89  ? 190 LYS B N   1 
ATOM   4209  C CA  . LYS B 1 190 ? 89.272  131.835 130.379 1.00 55.89  ? 190 LYS B CA  1 
ATOM   4210  C C   . LYS B 1 190 ? 88.843  132.452 131.704 1.00 55.89  ? 190 LYS B C   1 
ATOM   4211  O O   . LYS B 1 190 ? 89.285  132.038 132.779 1.00 55.89  ? 190 LYS B O   1 
ATOM   4212  C CB  . LYS B 1 190 ? 88.342  130.680 130.012 1.00 55.89  ? 190 LYS B CB  1 
ATOM   4213  C CG  . LYS B 1 190 ? 88.690  130.000 128.700 1.00 55.89  ? 190 LYS B CG  1 
ATOM   4214  C CD  . LYS B 1 190 ? 87.441  129.558 127.954 1.00 55.89  ? 190 LYS B CD  1 
ATOM   4215  C CE  . LYS B 1 190 ? 86.591  128.622 128.796 1.00 55.89  ? 190 LYS B CE  1 
ATOM   4216  N NZ  . LYS B 1 190 ? 85.266  128.361 128.169 1.00 55.89  ? 190 LYS B NZ  1 
ATOM   4217  N N   . GLU B 1 191 ? 87.976  133.462 131.615 1.00 66.17  ? 191 GLU B N   1 
ATOM   4218  C CA  . GLU B 1 191 ? 87.509  134.140 132.819 1.00 66.17  ? 191 GLU B CA  1 
ATOM   4219  C C   . GLU B 1 191 ? 86.728  133.194 133.720 1.00 66.17  ? 191 GLU B C   1 
ATOM   4220  O O   . GLU B 1 191 ? 86.875  133.229 134.947 1.00 66.17  ? 191 GLU B O   1 
ATOM   4221  C CB  . GLU B 1 191 ? 86.654  135.349 132.443 1.00 66.17  ? 191 GLU B CB  1 
ATOM   4222  C CG  . GLU B 1 191 ? 87.358  136.353 131.548 1.00 66.17  ? 191 GLU B CG  1 
ATOM   4223  C CD  . GLU B 1 191 ? 86.797  136.369 130.141 1.00 66.17  ? 191 GLU B CD  1 
ATOM   4224  O OE1 . GLU B 1 191 ? 86.326  135.310 129.677 1.00 66.17  ? 191 GLU B OE1 1 
ATOM   4225  O OE2 . GLU B 1 191 ? 86.827  137.440 129.499 1.00 66.17  ? 191 GLU B OE2 1 
ATOM   4226  N N   . GLU B 1 192 ? 85.891  132.344 133.133 1.00 65.81  ? 192 GLU B N   1 
ATOM   4227  C CA  . GLU B 1 192 ? 85.085  131.425 133.924 1.00 65.81  ? 192 GLU B CA  1 
ATOM   4228  C C   . GLU B 1 192 ? 85.950  130.317 134.511 1.00 65.81  ? 192 GLU B C   1 
ATOM   4229  O O   . GLU B 1 192 ? 86.802  129.741 133.830 1.00 65.81  ? 192 GLU B O   1 
ATOM   4230  C CB  . GLU B 1 192 ? 83.971  130.823 133.067 1.00 65.81  ? 192 GLU B CB  1 
ATOM   4231  C CG  . GLU B 1 192 ? 83.027  131.843 132.438 1.00 65.81  ? 192 GLU B CG  1 
ATOM   4232  C CD  . GLU B 1 192 ? 82.292  132.698 133.458 1.00 65.81  ? 192 GLU B CD  1 
ATOM   4233  O OE1 . GLU B 1 192 ? 81.742  133.747 133.061 1.00 65.81  ? 192 GLU B OE1 1 
ATOM   4234  O OE2 . GLU B 1 192 ? 82.235  132.315 134.646 1.00 65.81  ? 192 GLU B OE2 1 
ATOM   4235  N N   . LYS B 1 193 ? 85.725  130.023 135.790 1.00 48.66  ? 193 LYS B N   1 
ATOM   4236  C CA  . LYS B 1 193 ? 86.413  128.951 136.489 1.00 48.66  ? 193 LYS B CA  1 
ATOM   4237  C C   . LYS B 1 193 ? 85.395  128.114 137.250 1.00 48.66  ? 193 LYS B C   1 
ATOM   4238  O O   . LYS B 1 193 ? 84.383  128.628 137.732 1.00 48.66  ? 193 LYS B O   1 
ATOM   4239  C CB  . LYS B 1 193 ? 87.473  129.496 137.452 1.00 48.66  ? 193 LYS B CB  1 
ATOM   4240  C CG  . LYS B 1 193 ? 88.534  130.341 136.777 1.00 48.66  ? 193 LYS B CG  1 
ATOM   4241  C CD  . LYS B 1 193 ? 89.608  130.764 137.758 1.00 48.66  ? 193 LYS B CD  1 
ATOM   4242  C CE  . LYS B 1 193 ? 90.739  131.488 137.054 1.00 48.66  ? 193 LYS B CE  1 
ATOM   4243  N NZ  . LYS B 1 193 ? 90.256  132.714 136.368 1.00 48.66  ? 193 LYS B NZ  1 
ATOM   4244  N N   . ASP B 1 194 ? 85.672  126.819 137.351 1.00 44.60  ? 194 ASP B N   1 
ATOM   4245  C CA  . ASP B 1 194 ? 84.764  125.873 137.983 1.00 44.60  ? 194 ASP B CA  1 
ATOM   4246  C C   . ASP B 1 194 ? 85.234  125.557 139.396 1.00 44.60  ? 194 ASP B C   1 
ATOM   4247  O O   . ASP B 1 194 ? 86.432  125.388 139.639 1.00 44.60  ? 194 ASP B O   1 
ATOM   4248  C CB  . ASP B 1 194 ? 84.668  124.582 137.169 1.00 44.60  ? 194 ASP B CB  1 
ATOM   4249  C CG  . ASP B 1 194 ? 84.292  124.831 135.723 1.00 44.60  ? 194 ASP B CG  1 
ATOM   4250  O OD1 . ASP B 1 194 ? 84.346  125.999 135.286 1.00 44.60  ? 194 ASP B OD1 1 
ATOM   4251  O OD2 . ASP B 1 194 ? 83.946  123.858 135.022 1.00 44.60  ? 194 ASP B OD2 1 
ATOM   4252  N N   . LEU B 1 195 ? 84.284  125.479 140.324 1.00 34.60  ? 195 LEU B N   1 
ATOM   4253  C CA  . LEU B 1 195 ? 84.560  125.140 141.714 1.00 34.60  ? 195 LEU B CA  1 
ATOM   4254  C C   . LEU B 1 195 ? 83.703  123.946 142.105 1.00 34.60  ? 195 LEU B C   1 
ATOM   4255  O O   . LEU B 1 195 ? 82.476  123.992 141.974 1.00 34.60  ? 195 LEU B O   1 
ATOM   4256  C CB  . LEU B 1 195 ? 84.274  126.324 142.636 1.00 34.60  ? 195 LEU B CB  1 
ATOM   4257  C CG  . LEU B 1 195 ? 84.771  127.688 142.166 1.00 34.60  ? 195 LEU B CG  1 
ATOM   4258  C CD1 . LEU B 1 195 ? 84.114  128.779 142.980 1.00 34.60  ? 195 LEU B CD1 1 
ATOM   4259  C CD2 . LEU B 1 195 ? 86.277  127.768 142.279 1.00 34.60  ? 195 LEU B CD2 1 
ATOM   4260  N N   . ARG B 1 196 ? 84.346  122.888 142.591 1.00 35.76  ? 196 ARG B N   1 
ATOM   4261  C CA  . ARG B 1 196 ? 83.643  121.682 142.997 1.00 35.76  ? 196 ARG B CA  1 
ATOM   4262  C C   . ARG B 1 196 ? 84.286  121.125 144.257 1.00 35.76  ? 196 ARG B C   1 
ATOM   4263  O O   . ARG B 1 196 ? 85.424  121.455 144.595 1.00 35.76  ? 196 ARG B O   1 
ATOM   4264  C CB  . ARG B 1 196 ? 83.650  120.620 141.890 1.00 35.76  ? 196 ARG B CB  1 
ATOM   4265  C CG  . ARG B 1 196 ? 82.751  120.943 140.711 1.00 35.76  ? 196 ARG B CG  1 
ATOM   4266  C CD  . ARG B 1 196 ? 82.426  119.697 139.905 1.00 35.76  ? 196 ARG B CD  1 
ATOM   4267  N NE  . ARG B 1 196 ? 83.349  119.502 138.794 1.00 35.76  ? 196 ARG B NE  1 
ATOM   4268  C CZ  . ARG B 1 196 ? 84.482  118.818 138.870 1.00 35.76  ? 196 ARG B CZ  1 
ATOM   4269  N NH1 . ARG B 1 196 ? 84.875  118.255 140.001 1.00 35.76  ? 196 ARG B NH1 1 
ATOM   4270  N NH2 . ARG B 1 196 ? 85.237  118.691 137.784 1.00 35.76  ? 196 ARG B NH2 1 
ATOM   4271  N N   . TYR B 1 197 ? 83.538  120.273 144.952 1.00 35.78  ? 197 TYR B N   1 
ATOM   4272  C CA  . TYR B 1 197 ? 84.010  119.627 146.169 1.00 35.78  ? 197 TYR B CA  1 
ATOM   4273  C C   . TYR B 1 197 ? 84.439  118.204 145.835 1.00 35.78  ? 197 TYR B C   1 
ATOM   4274  O O   . TYR B 1 197 ? 83.614  117.385 145.417 1.00 35.78  ? 197 TYR B O   1 
ATOM   4275  C CB  . TYR B 1 197 ? 82.928  119.614 147.249 1.00 35.78  ? 197 TYR B CB  1 
ATOM   4276  C CG  . TYR B 1 197 ? 82.494  120.978 147.739 1.00 35.78  ? 197 TYR B CG  1 
ATOM   4277  C CD1 . TYR B 1 197 ? 83.139  122.132 147.320 1.00 35.78  ? 197 TYR B CD1 1 
ATOM   4278  C CD2 . TYR B 1 197 ? 81.439  121.107 148.630 1.00 35.78  ? 197 TYR B CD2 1 
ATOM   4279  C CE1 . TYR B 1 197 ? 82.741  123.374 147.767 1.00 35.78  ? 197 TYR B CE1 1 
ATOM   4280  C CE2 . TYR B 1 197 ? 81.035  122.345 149.085 1.00 35.78  ? 197 TYR B CE2 1 
ATOM   4281  C CZ  . TYR B 1 197 ? 81.690  123.475 148.650 1.00 35.78  ? 197 TYR B CZ  1 
ATOM   4282  O OH  . TYR B 1 197 ? 81.292  124.711 149.099 1.00 35.78  ? 197 TYR B OH  1 
ATOM   4283  N N   . CYS B 1 198 ? 85.728  117.915 146.014 1.00 37.30  ? 198 CYS B N   1 
ATOM   4284  C CA  . CYS B 1 198 ? 86.217  116.562 145.772 1.00 37.30  ? 198 CYS B CA  1 
ATOM   4285  C C   . CYS B 1 198 ? 85.815  115.615 146.897 1.00 37.30  ? 198 CYS B C   1 
ATOM   4286  O O   . CYS B 1 198 ? 85.421  114.473 146.635 1.00 37.30  ? 198 CYS B O   1 
ATOM   4287  C CB  . CYS B 1 198 ? 87.733  116.588 145.589 1.00 37.30  ? 198 CYS B CB  1 
ATOM   4288  S SG  . CYS B 1 198 ? 88.507  118.118 146.160 1.00 37.30  ? 198 CYS B SG  1 
ATOM   4289  N N   . THR B 1 199 ? 85.900  116.080 148.144 1.00 30.68  ? 199 THR B N   1 
ATOM   4290  C CA  . THR B 1 199 ? 85.534  115.342 149.362 1.00 30.68  ? 199 THR B CA  1 
ATOM   4291  C C   . THR B 1 199 ? 85.876  113.855 149.257 1.00 30.68  ? 199 THR B C   1 
ATOM   4292  O O   . THR B 1 199 ? 85.030  112.973 149.399 1.00 30.68  ? 199 THR B O   1 
ATOM   4293  C CB  . THR B 1 199 ? 84.061  115.553 149.738 1.00 30.68  ? 199 THR B CB  1 
ATOM   4294  O OG1 . THR B 1 199 ? 83.728  114.706 150.844 1.00 30.68  ? 199 THR B OG1 1 
ATOM   4295  C CG2 . THR B 1 199 ? 83.110  115.257 148.583 1.00 30.68  ? 199 THR B CG2 1 
ATOM   4296  N N   . LYS B 1 200 ? 87.157  113.593 149.014 1.00 32.26  ? 200 LYS B N   1 
ATOM   4297  C CA  . LYS B 1 200 ? 87.624  112.231 148.810 1.00 32.26  ? 200 LYS B CA  1 
ATOM   4298  C C   . LYS B 1 200 ? 87.518  111.409 150.090 1.00 32.26  ? 200 LYS B C   1 
ATOM   4299  O O   . LYS B 1 200 ? 87.600  111.933 151.203 1.00 32.26  ? 200 LYS B O   1 
ATOM   4300  C CB  . LYS B 1 200 ? 89.068  112.233 148.319 1.00 32.26  ? 200 LYS B CB  1 
ATOM   4301  C CG  . LYS B 1 200 ? 90.009  113.031 149.195 1.00 32.26  ? 200 LYS B CG  1 
ATOM   4302  C CD  . LYS B 1 200 ? 91.403  113.062 148.605 1.00 32.26  ? 200 LYS B CD  1 
ATOM   4303  C CE  . LYS B 1 200 ? 91.377  113.485 147.148 1.00 32.26  ? 200 LYS B CE  1 
ATOM   4304  N NZ  . LYS B 1 200 ? 92.750  113.721 146.625 1.00 32.26  ? 200 LYS B NZ  1 
ATOM   4305  N N   . HIS B 1 201 ? 87.336  110.103 149.915 1.00 35.32  ? 201 HIS B N   1 
ATOM   4306  C CA  . HIS B 1 201 ? 87.216  109.156 151.016 1.00 35.32  ? 201 HIS B CA  1 
ATOM   4307  C C   . HIS B 1 201 ? 88.426  108.233 151.012 1.00 35.32  ? 201 HIS B C   1 
ATOM   4308  O O   . HIS B 1 201 ? 88.689  107.557 150.012 1.00 35.32  ? 201 HIS B O   1 
ATOM   4309  C CB  . HIS B 1 201 ? 85.933  108.337 150.895 1.00 35.32  ? 201 HIS B CB  1 
ATOM   4310  C CG  . HIS B 1 201 ? 84.702  109.068 151.327 1.00 35.32  ? 201 HIS B CG  1 
ATOM   4311  N ND1 . HIS B 1 201 ? 84.226  110.180 150.667 1.00 35.32  ? 201 HIS B ND1 1 
ATOM   4312  C CD2 . HIS B 1 201 ? 83.843  108.841 152.348 1.00 35.32  ? 201 HIS B CD2 1 
ATOM   4313  C CE1 . HIS B 1 201 ? 83.130  110.609 151.265 1.00 35.32  ? 201 HIS B CE1 1 
ATOM   4314  N NE2 . HIS B 1 201 ? 82.875  109.814 152.288 1.00 35.32  ? 201 HIS B NE2 1 
ATOM   4315  N N   . TYR B 1 202 ? 89.147  108.196 152.126 1.00 36.14  ? 202 TYR B N   1 
ATOM   4316  C CA  . TYR B 1 202 ? 90.240  107.259 152.319 1.00 36.14  ? 202 TYR B CA  1 
ATOM   4317  C C   . TYR B 1 202 ? 89.771  106.110 153.205 1.00 36.14  ? 202 TYR B C   1 
ATOM   4318  O O   . TYR B 1 202 ? 88.625  106.066 153.658 1.00 36.14  ? 202 TYR B O   1 
ATOM   4319  C CB  . TYR B 1 202 ? 91.455  107.959 152.927 1.00 36.14  ? 202 TYR B CB  1 
ATOM   4320  C CG  . TYR B 1 202 ? 92.152  108.920 151.997 1.00 36.14  ? 202 TYR B CG  1 
ATOM   4321  C CD1 . TYR B 1 202 ? 92.814  108.465 150.868 1.00 36.14  ? 202 TYR B CD1 1 
ATOM   4322  C CD2 . TYR B 1 202 ? 92.156  110.282 152.253 1.00 36.14  ? 202 TYR B CD2 1 
ATOM   4323  C CE1 . TYR B 1 202 ? 93.457  109.342 150.018 1.00 36.14  ? 202 TYR B CE1 1 
ATOM   4324  C CE2 . TYR B 1 202 ? 92.797  111.165 151.410 1.00 36.14  ? 202 TYR B CE2 1 
ATOM   4325  C CZ  . TYR B 1 202 ? 93.445  110.690 150.296 1.00 36.14  ? 202 TYR B CZ  1 
ATOM   4326  O OH  . TYR B 1 202 ? 94.084  111.568 149.454 1.00 36.14  ? 202 TYR B OH  1 
ATOM   4327  N N   . ASN B 1 203 ? 90.673  105.161 153.456 1.00 37.77  ? 203 ASN B N   1 
ATOM   4328  C CA  . ASN B 1 203 ? 90.338  104.043 154.327 1.00 37.77  ? 203 ASN B CA  1 
ATOM   4329  C C   . ASN B 1 203 ? 90.364  104.419 155.802 1.00 37.77  ? 203 ASN B C   1 
ATOM   4330  O O   . ASN B 1 203 ? 89.781  103.700 156.619 1.00 37.77  ? 203 ASN B O   1 
ATOM   4331  C CB  . ASN B 1 203 ? 91.290  102.873 154.082 1.00 37.77  ? 203 ASN B CB  1 
ATOM   4332  C CG  . ASN B 1 203 ? 92.739  103.264 154.241 1.00 37.77  ? 203 ASN B CG  1 
ATOM   4333  O OD1 . ASN B 1 203 ? 93.106  104.419 154.034 1.00 37.77  ? 203 ASN B OD1 1 
ATOM   4334  N ND2 . ASN B 1 203 ? 93.575  102.302 154.611 1.00 37.77  ? 203 ASN B ND2 1 
ATOM   4335  N N   . THR B 1 204 ? 91.024  105.519 156.161 1.00 39.44  ? 204 THR B N   1 
ATOM   4336  C CA  . THR B 1 204 ? 91.096  105.952 157.550 1.00 39.44  ? 204 THR B CA  1 
ATOM   4337  C C   . THR B 1 204 ? 89.982  106.912 157.941 1.00 39.44  ? 204 THR B C   1 
ATOM   4338  O O   . THR B 1 204 ? 89.862  107.243 159.125 1.00 39.44  ? 204 THR B O   1 
ATOM   4339  C CB  . THR B 1 204 ? 92.445  106.617 157.833 1.00 39.44  ? 204 THR B CB  1 
ATOM   4340  O OG1 . THR B 1 204 ? 92.568  107.804 157.042 1.00 39.44  ? 204 THR B OG1 1 
ATOM   4341  C CG2 . THR B 1 204 ? 93.579  105.671 157.497 1.00 39.44  ? 204 THR B CG2 1 
ATOM   4342  N N   . GLY B 1 205 ? 89.180  107.368 156.995 1.00 39.60  ? 205 GLY B N   1 
ATOM   4343  C CA  . GLY B 1 205 ? 88.094  108.275 157.293 1.00 39.60  ? 205 GLY B CA  1 
ATOM   4344  C C   . GLY B 1 205 ? 87.812  109.168 156.102 1.00 39.60  ? 205 GLY B C   1 
ATOM   4345  O O   . GLY B 1 205 ? 88.403  109.021 155.038 1.00 39.60  ? 205 GLY B O   1 
ATOM   4346  N N   . LYS B 1 206 ? 86.891  110.102 156.311 1.00 35.62  ? 206 LYS B N   1 
ATOM   4347  C CA  . LYS B 1 206 ? 86.474  111.040 155.278 1.00 35.62  ? 206 LYS B CA  1 
ATOM   4348  C C   . LYS B 1 206 ? 87.166  112.376 155.511 1.00 35.62  ? 206 LYS B C   1 
ATOM   4349  O O   . LYS B 1 206 ? 87.001  112.987 156.571 1.00 35.62  ? 206 LYS B O   1 
ATOM   4350  C CB  . LYS B 1 206 ? 84.956  111.211 155.286 1.00 35.62  ? 206 LYS B CB  1 
ATOM   4351  C CG  . LYS B 1 206 ? 84.426  112.060 154.150 1.00 35.62  ? 206 LYS B CG  1 
ATOM   4352  C CD  . LYS B 1 206 ? 83.057  112.625 154.479 1.00 35.62  ? 206 LYS B CD  1 
ATOM   4353  C CE  . LYS B 1 206 ? 82.125  111.551 155.009 1.00 35.62  ? 206 LYS B CE  1 
ATOM   4354  N NZ  . LYS B 1 206 ? 80.777  112.101 155.311 1.00 35.62  ? 206 LYS B NZ  1 
ATOM   4355  N N   . PHE B 1 207 ? 87.929  112.830 154.522 1.00 32.84  ? 207 PHE B N   1 
ATOM   4356  C CA  . PHE B 1 207 ? 88.691  114.066 154.619 1.00 32.84  ? 207 PHE B CA  1 
ATOM   4357  C C   . PHE B 1 207 ? 88.127  115.102 153.660 1.00 32.84  ? 207 PHE B C   1 
ATOM   4358  O O   . PHE B 1 207 ? 87.863  114.800 152.492 1.00 32.84  ? 207 PHE B O   1 
ATOM   4359  C CB  . PHE B 1 207 ? 90.170  113.826 154.312 1.00 32.84  ? 207 PHE B CB  1 
ATOM   4360  C CG  . PHE B 1 207 ? 90.885  113.038 155.365 1.00 32.84  ? 207 PHE B CG  1 
ATOM   4361  C CD1 . PHE B 1 207 ? 90.343  112.895 156.628 1.00 32.84  ? 207 PHE B CD1 1 
ATOM   4362  C CD2 . PHE B 1 207 ? 92.100  112.438 155.094 1.00 32.84  ? 207 PHE B CD2 1 
ATOM   4363  C CE1 . PHE B 1 207 ? 90.997  112.169 157.598 1.00 32.84  ? 207 PHE B CE1 1 
ATOM   4364  C CE2 . PHE B 1 207 ? 92.758  111.711 156.061 1.00 32.84  ? 207 PHE B CE2 1 
ATOM   4365  C CZ  . PHE B 1 207 ? 92.206  111.576 157.313 1.00 32.84  ? 207 PHE B CZ  1 
ATOM   4366  N N   . THR B 1 208 ? 87.948  116.322 154.157 1.00 31.42  ? 208 THR B N   1 
ATOM   4367  C CA  . THR B 1 208 ? 87.410  117.395 153.337 1.00 31.42  ? 208 THR B CA  1 
ATOM   4368  C C   . THR B 1 208 ? 88.369  117.739 152.207 1.00 31.42  ? 208 THR B C   1 
ATOM   4369  O O   . THR B 1 208 ? 89.583  117.559 152.318 1.00 31.42  ? 208 THR B O   1 
ATOM   4370  C CB  . THR B 1 208 ? 87.151  118.637 154.181 1.00 31.42  ? 208 THR B CB  1 
ATOM   4371  O OG1 . THR B 1 208 ? 86.847  119.740 153.319 1.00 31.42  ? 208 THR B OG1 1 
ATOM   4372  C CG2 . THR B 1 208 ? 88.377  118.972 155.001 1.00 31.42  ? 208 THR B CG2 1 
ATOM   4373  N N   . CYS B 1 209 ? 87.812  118.237 151.108 1.00 31.55  ? 209 CYS B N   1 
ATOM   4374  C CA  . CYS B 1 209 ? 88.611  118.538 149.932 1.00 31.55  ? 209 CYS B CA  1 
ATOM   4375  C C   . CYS B 1 209 ? 87.937  119.645 149.137 1.00 31.55  ? 209 CYS B C   1 
ATOM   4376  O O   . CYS B 1 209 ? 86.711  119.775 149.142 1.00 31.55  ? 209 CYS B O   1 
ATOM   4377  C CB  . CYS B 1 209 ? 88.804  117.293 149.062 1.00 31.55  ? 209 CYS B CB  1 
ATOM   4378  S SG  . CYS B 1 209 ? 89.819  117.529 147.592 1.00 31.55  ? 209 CYS B SG  1 
ATOM   4379  N N   . ILE B 1 210 ? 88.754  120.440 148.454 1.00 30.85  ? 210 ILE B N   1 
ATOM   4380  C CA  . ILE B 1 210 ? 88.285  121.573 147.665 1.00 30.85  ? 210 ILE B CA  1 
ATOM   4381  C C   . ILE B 1 210 ? 89.064  121.592 146.358 1.00 30.85  ? 210 ILE B C   1 
ATOM   4382  O O   . ILE B 1 210 ? 90.289  121.438 146.361 1.00 30.85  ? 210 ILE B O   1 
ATOM   4383  C CB  . ILE B 1 210 ? 88.459  122.901 148.423 1.00 30.85  ? 210 ILE B CB  1 
ATOM   4384  C CG1 . ILE B 1 210 ? 87.483  122.977 149.592 1.00 30.85  ? 210 ILE B CG1 1 
ATOM   4385  C CG2 . ILE B 1 210 ? 88.228  124.062 147.506 1.00 30.85  ? 210 ILE B CG2 1 
ATOM   4386  C CD1 . ILE B 1 210 ? 86.044  122.965 149.172 1.00 30.85  ? 210 ILE B CD1 1 
ATOM   4387  N N   . GLU B 1 211 ? 88.361  121.783 145.244 1.00 33.06  ? 211 GLU B N   1 
ATOM   4388  C CA  . GLU B 1 211 ? 88.957  121.669 143.920 1.00 33.06  ? 211 GLU B CA  1 
ATOM   4389  C C   . GLU B 1 211 ? 88.593  122.885 143.084 1.00 33.06  ? 211 GLU B C   1 
ATOM   4390  O O   . GLU B 1 211 ? 87.428  123.289 143.047 1.00 33.06  ? 211 GLU B O   1 
ATOM   4391  C CB  . GLU B 1 211 ? 88.488  120.385 143.231 1.00 33.06  ? 211 GLU B CB  1 
ATOM   4392  C CG  . GLU B 1 211 ? 88.376  120.470 141.723 1.00 33.06  ? 211 GLU B CG  1 
ATOM   4393  C CD  . GLU B 1 211 ? 88.171  119.109 141.082 1.00 33.06  ? 211 GLU B CD  1 
ATOM   4394  O OE1 . GLU B 1 211 ? 88.964  118.190 141.371 1.00 33.06  ? 211 GLU B OE1 1 
ATOM   4395  O OE2 . GLU B 1 211 ? 87.218  118.959 140.290 1.00 33.06  ? 211 GLU B OE2 1 
ATOM   4396  N N   . VAL B 1 212 ? 89.590  123.462 142.417 1.00 32.73  ? 212 VAL B N   1 
ATOM   4397  C CA  . VAL B 1 212 ? 89.401  124.580 141.500 1.00 32.73  ? 212 VAL B CA  1 
ATOM   4398  C C   . VAL B 1 212 ? 90.016  124.202 140.160 1.00 32.73  ? 212 VAL B C   1 
ATOM   4399  O O   . VAL B 1 212 ? 91.129  123.667 140.115 1.00 32.73  ? 212 VAL B O   1 
ATOM   4400  C CB  . VAL B 1 212 ? 90.026  125.879 142.043 1.00 32.73  ? 212 VAL B CB  1 
ATOM   4401  C CG1 . VAL B 1 212 ? 91.422  125.619 142.562 1.00 32.73  ? 212 VAL B CG1 1 
ATOM   4402  C CG2 . VAL B 1 212 ? 90.050  126.950 140.972 1.00 32.73  ? 212 VAL B CG2 1 
ATOM   4403  N N   . ARG B 1 213 ? 89.292  124.464 139.075 1.00 35.30  ? 213 ARG B N   1 
ATOM   4404  C CA  . ARG B 1 213 ? 89.716  124.075 137.738 1.00 35.30  ? 213 ARG B CA  1 
ATOM   4405  C C   . ARG B 1 213 ? 89.965  125.305 136.879 1.00 35.30  ? 213 ARG B C   1 
ATOM   4406  O O   . ARG B 1 213 ? 89.188  126.263 136.910 1.00 35.30  ? 213 ARG B O   1 
ATOM   4407  C CB  . ARG B 1 213 ? 88.669  123.190 137.067 1.00 35.30  ? 213 ARG B CB  1 
ATOM   4408  C CG  . ARG B 1 213 ? 88.180  122.055 137.935 1.00 35.30  ? 213 ARG B CG  1 
ATOM   4409  C CD  . ARG B 1 213 ? 87.146  121.224 137.207 1.00 35.30  ? 213 ARG B CD  1 
ATOM   4410  N NE  . ARG B 1 213 ? 87.743  120.425 136.145 1.00 35.30  ? 213 ARG B NE  1 
ATOM   4411  C CZ  . ARG B 1 213 ? 88.234  119.205 136.313 1.00 35.30  ? 213 ARG B CZ  1 
ATOM   4412  N NH1 . ARG B 1 213 ? 88.221  118.612 137.495 1.00 35.30  ? 213 ARG B NH1 1 
ATOM   4413  N NH2 . ARG B 1 213 ? 88.754  118.565 135.269 1.00 35.30  ? 213 ARG B NH2 1 
ATOM   4414  N N   . PHE B 1 214 ? 91.049  125.268 136.110 1.00 36.60  ? 214 PHE B N   1 
ATOM   4415  C CA  . PHE B 1 214 ? 91.373  126.303 135.139 1.00 36.60  ? 214 PHE B CA  1 
ATOM   4416  C C   . PHE B 1 214 ? 91.171  125.749 133.738 1.00 36.60  ? 214 PHE B C   1 
ATOM   4417  O O   . PHE B 1 214 ? 91.653  124.656 133.426 1.00 36.60  ? 214 PHE B O   1 
ATOM   4418  C CB  . PHE B 1 214 ? 92.816  126.783 135.298 1.00 36.60  ? 214 PHE B CB  1 
ATOM   4419  C CG  . PHE B 1 214 ? 93.160  127.225 136.684 1.00 36.60  ? 214 PHE B CG  1 
ATOM   4420  C CD1 . PHE B 1 214 ? 92.787  128.475 137.138 1.00 36.60  ? 214 PHE B CD1 1 
ATOM   4421  C CD2 . PHE B 1 214 ? 93.865  126.394 137.530 1.00 36.60  ? 214 PHE B CD2 1 
ATOM   4422  C CE1 . PHE B 1 214 ? 93.107  128.883 138.414 1.00 36.60  ? 214 PHE B CE1 1 
ATOM   4423  C CE2 . PHE B 1 214 ? 94.187  126.797 138.804 1.00 36.60  ? 214 PHE B CE2 1 
ATOM   4424  C CZ  . PHE B 1 214 ? 93.807  128.042 139.248 1.00 36.60  ? 214 PHE B CZ  1 
ATOM   4425  N N   . HIS B 1 215 ? 90.463  126.498 132.897 1.00 41.19  ? 215 HIS B N   1 
ATOM   4426  C CA  . HIS B 1 215 ? 90.263  126.115 131.504 1.00 41.19  ? 215 HIS B CA  1 
ATOM   4427  C C   . HIS B 1 215 ? 91.323  126.809 130.658 1.00 41.19  ? 215 HIS B C   1 
ATOM   4428  O O   . HIS B 1 215 ? 91.221  128.008 130.384 1.00 41.19  ? 215 HIS B O   1 
ATOM   4429  C CB  . HIS B 1 215 ? 88.859  126.481 131.034 1.00 41.19  ? 215 HIS B CB  1 
ATOM   4430  C CG  . HIS B 1 215 ? 87.767  125.796 131.794 1.00 41.19  ? 215 HIS B CG  1 
ATOM   4431  N ND1 . HIS B 1 215 ? 87.658  124.424 131.864 1.00 41.19  ? 215 HIS B ND1 1 
ATOM   4432  C CD2 . HIS B 1 215 ? 86.731  126.293 132.510 1.00 41.19  ? 215 HIS B CD2 1 
ATOM   4433  C CE1 . HIS B 1 215 ? 86.604  124.106 132.595 1.00 41.19  ? 215 HIS B CE1 1 
ATOM   4434  N NE2 . HIS B 1 215 ? 86.024  125.222 132.999 1.00 41.19  ? 215 HIS B NE2 1 
ATOM   4435  N N   . LEU B 1 216 ? 92.336  126.058 130.241 1.00 41.58  ? 216 LEU B N   1 
ATOM   4436  C CA  . LEU B 1 216 ? 93.429  126.582 129.435 1.00 41.58  ? 216 LEU B CA  1 
ATOM   4437  C C   . LEU B 1 216 ? 93.292  126.081 128.007 1.00 41.58  ? 216 LEU B C   1 
ATOM   4438  O O   . LEU B 1 216 ? 93.138  124.876 127.780 1.00 41.58  ? 216 LEU B O   1 
ATOM   4439  C CB  . LEU B 1 216 ? 94.786  126.162 130.002 1.00 41.58  ? 216 LEU B CB  1 
ATOM   4440  C CG  . LEU B 1 216 ? 95.124  126.580 131.430 1.00 41.58  ? 216 LEU B CG  1 
ATOM   4441  C CD1 . LEU B 1 216 ? 94.789  125.471 132.405 1.00 41.58  ? 216 LEU B CD1 1 
ATOM   4442  C CD2 . LEU B 1 216 ? 96.589  126.946 131.531 1.00 41.58  ? 216 LEU B CD2 1 
ATOM   4443  N N   . GLU B 1 217 ? 93.352  127.000 127.050 1.00 47.21  ? 217 GLU B N   1 
ATOM   4444  C CA  . GLU B 1 217 ? 93.385  126.657 125.638 1.00 47.21  ? 217 GLU B CA  1 
ATOM   4445  C C   . GLU B 1 217 ? 94.704  127.122 125.043 1.00 47.21  ? 217 GLU B C   1 
ATOM   4446  O O   . GLU B 1 217 ? 95.300  128.101 125.503 1.00 47.21  ? 217 GLU B O   1 
ATOM   4447  C CB  . GLU B 1 217 ? 92.218  127.282 124.872 1.00 47.21  ? 217 GLU B CB  1 
ATOM   4448  C CG  . GLU B 1 217 ? 92.048  128.769 125.096 1.00 47.21  ? 217 GLU B CG  1 
ATOM   4449  C CD  . GLU B 1 217 ? 90.632  129.232 124.831 1.00 47.21  ? 217 GLU B CD  1 
ATOM   4450  O OE1 . GLU B 1 217 ? 89.811  129.208 125.771 1.00 47.21  ? 217 GLU B OE1 1 
ATOM   4451  O OE2 . GLU B 1 217 ? 90.337  129.616 123.680 1.00 47.21  ? 217 GLU B OE2 1 
ATOM   4452  N N   . ARG B 1 218 ? 95.159  126.409 124.021 1.00 42.95  ? 218 ARG B N   1 
ATOM   4453  C CA  . ARG B 1 218 ? 96.449  126.669 123.399 1.00 42.95  ? 218 ARG B CA  1 
ATOM   4454  C C   . ARG B 1 218 ? 96.235  127.394 122.079 1.00 42.95  ? 218 ARG B C   1 
ATOM   4455  O O   . ARG B 1 218 ? 95.490  126.915 121.218 1.00 42.95  ? 218 ARG B O   1 
ATOM   4456  C CB  . ARG B 1 218 ? 97.211  125.365 123.174 1.00 42.95  ? 218 ARG B CB  1 
ATOM   4457  C CG  . ARG B 1 218 ? 98.333  125.469 122.162 1.00 42.95  ? 218 ARG B CG  1 
ATOM   4458  C CD  . ARG B 1 218 ? 99.472  124.543 122.534 1.00 42.95  ? 218 ARG B CD  1 
ATOM   4459  N NE  . ARG B 1 218 ? 98.978  123.282 123.070 1.00 42.95  ? 218 ARG B NE  1 
ATOM   4460  C CZ  . ARG B 1 218 ? 99.698  122.449 123.807 1.00 42.95  ? 218 ARG B CZ  1 
ATOM   4461  N NH1 . ARG B 1 218 ? 100.954 122.717 124.123 1.00 42.95  ? 218 ARG B NH1 1 
ATOM   4462  N NH2 . ARG B 1 218 ? 99.144  121.320 124.238 1.00 42.95  ? 218 ARG B NH2 1 
ATOM   4463  N N   . GLN B 1 219 ? 96.880  128.546 121.925 1.00 42.83  ? 219 GLN B N   1 
ATOM   4464  C CA  . GLN B 1 219 ? 96.851  129.249 120.654 1.00 42.83  ? 219 GLN B CA  1 
ATOM   4465  C C   . GLN B 1 219 ? 97.804  128.573 119.680 1.00 42.83  ? 219 GLN B C   1 
ATOM   4466  O O   . GLN B 1 219 ? 98.880  128.100 120.061 1.00 42.83  ? 219 GLN B O   1 
ATOM   4467  C CB  . GLN B 1 219 ? 97.207  130.725 120.840 1.00 42.83  ? 219 GLN B CB  1 
ATOM   4468  C CG  . GLN B 1 219 ? 98.690  131.044 120.886 1.00 42.83  ? 219 GLN B CG  1 
ATOM   4469  C CD  . GLN B 1 219 ? 99.344  130.609 122.179 1.00 42.83  ? 219 GLN B CD  1 
ATOM   4470  O OE1 . GLN B 1 219 ? 99.423  129.420 122.479 1.00 42.83  ? 219 GLN B OE1 1 
ATOM   4471  N NE2 . GLN B 1 219 ? 99.813  131.576 122.958 1.00 42.83  ? 219 GLN B NE2 1 
ATOM   4472  N N   . MET B 1 220 ? 97.390  128.505 118.420 1.00 51.36  ? 220 MET B N   1 
ATOM   4473  C CA  . MET B 1 220 ? 98.077  127.710 117.415 1.00 51.36  ? 220 MET B CA  1 
ATOM   4474  C C   . MET B 1 220 ? 99.045  128.517 116.566 1.00 51.36  ? 220 MET B C   1 
ATOM   4475  O O   . MET B 1 220 ? 99.629  127.960 115.634 1.00 51.36  ? 220 MET B O   1 
ATOM   4476  C CB  . MET B 1 220 ? 97.054  127.021 116.506 1.00 51.36  ? 220 MET B CB  1 
ATOM   4477  C CG  . MET B 1 220 ? 95.948  127.939 116.008 1.00 51.36  ? 220 MET B CG  1 
ATOM   4478  S SD  . MET B 1 220 ? 94.679  128.226 117.253 1.00 51.36  ? 220 MET B SD  1 
ATOM   4479  C CE  . MET B 1 220 ? 93.605  126.820 116.989 1.00 51.36  ? 220 MET B CE  1 
ATOM   4480  N N   . GLY B 1 221 ? 99.236  129.800 116.863 1.00 46.19  ? 221 GLY B N   1 
ATOM   4481  C CA  . GLY B 1 221 ? 100.019 130.670 116.004 1.00 46.19  ? 221 GLY B CA  1 
ATOM   4482  C C   . GLY B 1 221 ? 101.415 130.158 115.703 1.00 46.19  ? 221 GLY B C   1 
ATOM   4483  O O   . GLY B 1 221 ? 101.783 129.986 114.530 1.00 46.19  ? 221 GLY B O   1 
ATOM   4484  N N   . TYR B 1 222 ? 102.198 129.891 116.754 1.00 52.66  ? 222 TYR B N   1 
ATOM   4485  C CA  . TYR B 1 222 ? 103.553 129.394 116.542 1.00 52.66  ? 222 TYR B CA  1 
ATOM   4486  C C   . TYR B 1 222 ? 103.530 128.050 115.840 1.00 52.66  ? 222 TYR B C   1 
ATOM   4487  O O   . TYR B 1 222 ? 104.324 127.804 114.930 1.00 52.66  ? 222 TYR B O   1 
ATOM   4488  C CB  . TYR B 1 222 ? 104.307 129.248 117.859 1.00 52.66  ? 222 TYR B CB  1 
ATOM   4489  C CG  . TYR B 1 222 ? 105.353 128.157 117.760 1.00 52.66  ? 222 TYR B CG  1 
ATOM   4490  C CD1 . TYR B 1 222 ? 106.555 128.376 117.100 1.00 52.66  ? 222 TYR B CD1 1 
ATOM   4491  C CD2 . TYR B 1 222 ? 105.106 126.885 118.254 1.00 52.66  ? 222 TYR B CD2 1 
ATOM   4492  C CE1 . TYR B 1 222 ? 107.488 127.375 116.978 1.00 52.66  ? 222 TYR B CE1 1 
ATOM   4493  C CE2 . TYR B 1 222 ? 106.036 125.872 118.134 1.00 52.66  ? 222 TYR B CE2 1 
ATOM   4494  C CZ  . TYR B 1 222 ? 107.228 126.122 117.498 1.00 52.66  ? 222 TYR B CZ  1 
ATOM   4495  O OH  . TYR B 1 222 ? 108.168 125.120 117.378 1.00 52.66  ? 222 TYR B OH  1 
ATOM   4496  N N   . TYR B 1 223 ? 102.666 127.143 116.292 1.00 51.98  ? 223 TYR B N   1 
ATOM   4497  C CA  . TYR B 1 223 ? 102.670 125.803 115.721 1.00 51.98  ? 223 TYR B CA  1 
ATOM   4498  C C   . TYR B 1 223 ? 102.240 125.844 114.264 1.00 51.98  ? 223 TYR B C   1 
ATOM   4499  O O   . TYR B 1 223 ? 102.815 125.147 113.417 1.00 51.98  ? 223 TYR B O   1 
ATOM   4500  C CB  . TYR B 1 223 ? 101.771 124.873 116.530 1.00 51.98  ? 223 TYR B CB  1 
ATOM   4501  C CG  . TYR B 1 223 ? 102.525 124.121 117.599 1.00 51.98  ? 223 TYR B CG  1 
ATOM   4502  C CD1 . TYR B 1 223 ? 103.432 123.123 117.270 1.00 51.98  ? 223 TYR B CD1 1 
ATOM   4503  C CD2 . TYR B 1 223 ? 102.336 124.417 118.941 1.00 51.98  ? 223 TYR B CD2 1 
ATOM   4504  C CE1 . TYR B 1 223 ? 104.127 122.444 118.247 1.00 51.98  ? 223 TYR B CE1 1 
ATOM   4505  C CE2 . TYR B 1 223 ? 103.024 123.742 119.923 1.00 51.98  ? 223 TYR B CE2 1 
ATOM   4506  C CZ  . TYR B 1 223 ? 103.919 122.755 119.570 1.00 51.98  ? 223 TYR B CZ  1 
ATOM   4507  O OH  . TYR B 1 223 ? 104.613 122.074 120.543 1.00 51.98  ? 223 TYR B OH  1 
ATOM   4508  N N   . LEU B 1 224 ? 101.255 126.686 113.950 1.00 52.40  ? 224 LEU B N   1 
ATOM   4509  C CA  . LEU B 1 224 ? 100.874 126.887 112.560 1.00 52.40  ? 224 LEU B CA  1 
ATOM   4510  C C   . LEU B 1 224 ? 102.067 127.348 111.735 1.00 52.40  ? 224 LEU B C   1 
ATOM   4511  O O   . LEU B 1 224 ? 102.446 126.685 110.764 1.00 52.40  ? 224 LEU B O   1 
ATOM   4512  C CB  . LEU B 1 224 ? 99.728  127.896 112.470 1.00 52.40  ? 224 LEU B CB  1 
ATOM   4513  C CG  . LEU B 1 224 ? 99.061  128.050 111.103 1.00 52.40  ? 224 LEU B CG  1 
ATOM   4514  C CD1 . LEU B 1 224 ? 97.551  128.125 111.261 1.00 52.40  ? 224 LEU B CD1 1 
ATOM   4515  C CD2 . LEU B 1 224 ? 99.589  129.278 110.385 1.00 52.40  ? 224 LEU B CD2 1 
ATOM   4516  N N   . ILE B 1 225 ? 102.729 128.427 112.169 1.00 54.34  ? 225 ILE B N   1 
ATOM   4517  C CA  . ILE B 1 225 ? 103.836 128.985 111.392 1.00 54.34  ? 225 ILE B CA  1 
ATOM   4518  C C   . ILE B 1 225 ? 104.971 127.975 111.255 1.00 54.34  ? 225 ILE B C   1 
ATOM   4519  O O   . ILE B 1 225 ? 105.602 127.866 110.196 1.00 54.34  ? 225 ILE B O   1 
ATOM   4520  C CB  . ILE B 1 225 ? 104.322 130.303 112.026 1.00 54.34  ? 225 ILE B CB  1 
ATOM   4521  C CG1 . ILE B 1 225 ? 103.489 131.481 111.516 1.00 54.34  ? 225 ILE B CG1 1 
ATOM   4522  C CG2 . ILE B 1 225 ? 105.804 130.530 111.752 1.00 54.34  ? 225 ILE B CG2 1 
ATOM   4523  C CD1 . ILE B 1 225 ? 103.406 132.642 112.484 1.00 54.34  ? 225 ILE B CD1 1 
ATOM   4524  N N   . GLN B 1 226 ? 105.238 127.210 112.312 1.00 57.47  ? 226 GLN B N   1 
ATOM   4525  C CA  . GLN B 1 226 ? 106.390 126.317 112.324 1.00 57.47  ? 226 GLN B CA  1 
ATOM   4526  C C   . GLN B 1 226 ? 106.150 125.056 111.503 1.00 57.47  ? 226 GLN B C   1 
ATOM   4527  O O   . GLN B 1 226 ? 107.083 124.543 110.876 1.00 57.47  ? 226 GLN B O   1 
ATOM   4528  C CB  . GLN B 1 226 ? 106.747 125.950 113.764 1.00 57.47  ? 226 GLN B CB  1 
ATOM   4529  C CG  . GLN B 1 226 ? 107.934 125.009 113.904 1.00 57.47  ? 226 GLN B CG  1 
ATOM   4530  C CD  . GLN B 1 226 ? 109.257 125.738 113.995 1.00 57.47  ? 226 GLN B CD  1 
ATOM   4531  O OE1 . GLN B 1 226 ? 109.333 126.841 114.533 1.00 57.47  ? 226 GLN B OE1 1 
ATOM   4532  N NE2 . GLN B 1 226 ? 110.310 125.122 113.471 1.00 57.47  ? 226 GLN B NE2 1 
ATOM   4533  N N   . MET B 1 227 ? 104.924 124.534 111.490 1.00 61.16  ? 227 MET B N   1 
ATOM   4534  C CA  . MET B 1 227 ? 104.662 123.247 110.861 1.00 61.16  ? 227 MET B CA  1 
ATOM   4535  C C   . MET B 1 227 ? 103.777 123.331 109.627 1.00 61.16  ? 227 MET B C   1 
ATOM   4536  O O   . MET B 1 227 ? 104.148 122.809 108.571 1.00 61.16  ? 227 MET B O   1 
ATOM   4537  C CB  . MET B 1 227 ? 104.033 122.287 111.880 1.00 61.16  ? 227 MET B CB  1 
ATOM   4538  C CG  . MET B 1 227 ? 104.819 122.165 113.172 1.00 61.16  ? 227 MET B CG  1 
ATOM   4539  S SD  . MET B 1 227 ? 106.586 121.999 112.866 1.00 61.16  ? 227 MET B SD  1 
ATOM   4540  C CE  . MET B 1 227 ? 106.816 120.246 113.116 1.00 61.16  ? 227 MET B CE  1 
ATOM   4541  N N   . TYR B 1 228 ? 102.608 123.965 109.724 1.00 56.12  ? 228 TYR B N   1 
ATOM   4542  C CA  . TYR B 1 228 ? 101.628 123.835 108.651 1.00 56.12  ? 228 TYR B CA  1 
ATOM   4543  C C   . TYR B 1 228 ? 102.067 124.578 107.395 1.00 56.12  ? 228 TYR B C   1 
ATOM   4544  O O   . TYR B 1 228 ? 101.952 124.048 106.284 1.00 56.12  ? 228 TYR B O   1 
ATOM   4545  C CB  . TYR B 1 228 ? 100.264 124.332 109.127 1.00 56.12  ? 228 TYR B CB  1 
ATOM   4546  C CG  . TYR B 1 228 ? 99.622  123.445 110.171 1.00 56.12  ? 228 TYR B CG  1 
ATOM   4547  C CD1 . TYR B 1 228 ? 98.816  122.378 109.801 1.00 56.12  ? 228 TYR B CD1 1 
ATOM   4548  C CD2 . TYR B 1 228 ? 99.816  123.677 111.524 1.00 56.12  ? 228 TYR B CD2 1 
ATOM   4549  C CE1 . TYR B 1 228 ? 98.227  121.566 110.748 1.00 56.12  ? 228 TYR B CE1 1 
ATOM   4550  C CE2 . TYR B 1 228 ? 99.228  122.871 112.478 1.00 56.12  ? 228 TYR B CE2 1 
ATOM   4551  C CZ  . TYR B 1 228 ? 98.436  121.817 112.084 1.00 56.12  ? 228 TYR B CZ  1 
ATOM   4552  O OH  . TYR B 1 228 ? 97.849  121.011 113.030 1.00 56.12  ? 228 TYR B OH  1 
ATOM   4553  N N   . ILE B 1 229 ? 102.570 125.803 107.548 1.00 56.89  ? 229 ILE B N   1 
ATOM   4554  C CA  . ILE B 1 229 ? 102.987 126.583 106.382 1.00 56.89  ? 229 ILE B CA  1 
ATOM   4555  C C   . ILE B 1 229 ? 104.133 125.922 105.622 1.00 56.89  ? 229 ILE B C   1 
ATOM   4556  O O   . ILE B 1 229 ? 104.055 125.839 104.384 1.00 56.89  ? 229 ILE B O   1 
ATOM   4557  C CB  . ILE B 1 229 ? 103.305 128.030 106.802 1.00 56.89  ? 229 ILE B CB  1 
ATOM   4558  C CG1 . ILE B 1 229 ? 102.059 128.695 107.388 1.00 56.89  ? 229 ILE B CG1 1 
ATOM   4559  C CG2 . ILE B 1 229 ? 103.824 128.828 105.621 1.00 56.89  ? 229 ILE B CG2 1 
ATOM   4560  C CD1 . ILE B 1 229 ? 100.857 128.640 106.479 1.00 56.89  ? 229 ILE B CD1 1 
ATOM   4561  N N   . PRO B 1 230 ? 105.213 125.455 106.267 1.00 59.22  ? 230 PRO B N   1 
ATOM   4562  C CA  . PRO B 1 230 ? 106.265 124.774 105.490 1.00 59.22  ? 230 PRO B CA  1 
ATOM   4563  C C   . PRO B 1 230 ? 105.761 123.571 104.714 1.00 59.22  ? 230 PRO B C   1 
ATOM   4564  O O   . PRO B 1 230 ? 106.183 123.354 103.571 1.00 59.22  ? 230 PRO B O   1 
ATOM   4565  C CB  . PRO B 1 230 ? 107.282 124.372 106.565 1.00 59.22  ? 230 PRO B CB  1 
ATOM   4566  C CG  . PRO B 1 230 ? 107.092 125.366 107.640 1.00 59.22  ? 230 PRO B CG  1 
ATOM   4567  C CD  . PRO B 1 230 ? 105.620 125.637 107.672 1.00 59.22  ? 230 PRO B CD  1 
ATOM   4568  N N   . SER B 1 231 ? 104.856 122.785 105.297 1.00 63.09  ? 231 SER B N   1 
ATOM   4569  C CA  . SER B 1 231 ? 104.315 121.634 104.583 1.00 63.09  ? 231 SER B CA  1 
ATOM   4570  C C   . SER B 1 231 ? 103.468 122.070 103.395 1.00 63.09  ? 231 SER B C   1 
ATOM   4571  O O   . SER B 1 231 ? 103.488 121.424 102.341 1.00 63.09  ? 231 SER B O   1 
ATOM   4572  C CB  . SER B 1 231 ? 103.491 120.769 105.528 1.00 63.09  ? 231 SER B CB  1 
ATOM   4573  O OG  . SER B 1 231 ? 102.143 121.190 105.510 1.00 63.09  ? 231 SER B OG  1 
ATOM   4574  N N   . LEU B 1 232 ? 102.697 123.148 103.553 1.00 61.26  ? 232 LEU B N   1 
ATOM   4575  C CA  . LEU B 1 232 ? 101.932 123.674 102.429 1.00 61.26  ? 232 LEU B CA  1 
ATOM   4576  C C   . LEU B 1 232 ? 102.857 124.116 101.303 1.00 61.26  ? 232 LEU B C   1 
ATOM   4577  O O   . LEU B 1 232 ? 102.590 123.850 100.124 1.00 61.26  ? 232 LEU B O   1 
ATOM   4578  C CB  . LEU B 1 232 ? 101.051 124.834 102.889 1.00 61.26  ? 232 LEU B CB  1 
ATOM   4579  C CG  . LEU B 1 232 ? 99.569  124.529 103.107 1.00 61.26  ? 232 LEU B CG  1 
ATOM   4580  C CD1 . LEU B 1 232 ? 98.940  123.972 101.842 1.00 61.26  ? 232 LEU B CD1 1 
ATOM   4581  C CD2 . LEU B 1 232 ? 99.389  123.568 104.263 1.00 61.26  ? 232 LEU B CD2 1 
ATOM   4582  N N   . LEU B 1 233 ? 103.958 124.783 101.648 1.00 64.71  ? 233 LEU B N   1 
ATOM   4583  C CA  . LEU B 1 233 ? 104.926 125.169 100.627 1.00 64.71  ? 233 LEU B CA  1 
ATOM   4584  C C   . LEU B 1 233 ? 105.524 123.942 99.947  1.00 64.71  ? 233 LEU B C   1 
ATOM   4585  O O   . LEU B 1 233 ? 105.705 123.926 98.723  1.00 64.71  ? 233 LEU B O   1 
ATOM   4586  C CB  . LEU B 1 233 ? 106.023 126.034 101.247 1.00 64.71  ? 233 LEU B CB  1 
ATOM   4587  C CG  . LEU B 1 233 ? 105.856 127.547 101.094 1.00 64.71  ? 233 LEU B CG  1 
ATOM   4588  C CD1 . LEU B 1 233 ? 106.056 127.963 99.646  1.00 64.71  ? 233 LEU B CD1 1 
ATOM   4589  C CD2 . LEU B 1 233 ? 104.493 128.000 101.600 1.00 64.71  ? 233 LEU B CD2 1 
ATOM   4590  N N   . ILE B 1 234 ? 105.825 122.899 100.724 1.00 66.80  ? 234 ILE B N   1 
ATOM   4591  C CA  . ILE B 1 234 ? 106.403 121.683 100.155 1.00 66.80  ? 234 ILE B CA  1 
ATOM   4592  C C   . ILE B 1 234 ? 105.428 121.022 99.187  1.00 66.80  ? 234 ILE B C   1 
ATOM   4593  O O   . ILE B 1 234 ? 105.817 120.574 98.101  1.00 66.80  ? 234 ILE B O   1 
ATOM   4594  C CB  . ILE B 1 234 ? 106.828 120.718 101.277 1.00 66.80  ? 234 ILE B CB  1 
ATOM   4595  C CG1 . ILE B 1 234 ? 108.035 121.275 102.030 1.00 66.80  ? 234 ILE B CG1 1 
ATOM   4596  C CG2 . ILE B 1 234 ? 107.148 119.347 100.712 1.00 66.80  ? 234 ILE B CG2 1 
ATOM   4597  C CD1 . ILE B 1 234 ? 109.142 121.763 101.129 1.00 66.80  ? 234 ILE B CD1 1 
ATOM   4598  N N   . VAL B 1 235 ? 104.150 120.941 99.562  1.00 68.99  ? 235 VAL B N   1 
ATOM   4599  C CA  . VAL B 1 235 ? 103.192 120.284 98.676  1.00 68.99  ? 235 VAL B CA  1 
ATOM   4600  C C   . VAL B 1 235 ? 102.919 121.136 97.440  1.00 68.99  ? 235 VAL B C   1 
ATOM   4601  O O   . VAL B 1 235 ? 102.672 120.598 96.357  1.00 68.99  ? 235 VAL B O   1 
ATOM   4602  C CB  . VAL B 1 235 ? 101.894 119.921 99.424  1.00 68.99  ? 235 VAL B CB  1 
ATOM   4603  C CG1 . VAL B 1 235 ? 102.196 118.992 100.590 1.00 68.99  ? 235 VAL B CG1 1 
ATOM   4604  C CG2 . VAL B 1 235 ? 101.163 121.156 99.894  1.00 68.99  ? 235 VAL B CG2 1 
ATOM   4605  N N   . ILE B 1 236 ? 102.972 122.466 97.559  1.00 70.59  ? 236 ILE B N   1 
ATOM   4606  C CA  . ILE B 1 236 ? 102.858 123.303 96.365  1.00 70.59  ? 236 ILE B CA  1 
ATOM   4607  C C   . ILE B 1 236 ? 104.060 123.089 95.449  1.00 70.59  ? 236 ILE B C   1 
ATOM   4608  O O   . ILE B 1 236 ? 103.934 123.078 94.216  1.00 70.59  ? 236 ILE B O   1 
ATOM   4609  C CB  . ILE B 1 236 ? 102.695 124.781 96.765  1.00 70.59  ? 236 ILE B CB  1 
ATOM   4610  C CG1 . ILE B 1 236 ? 101.344 125.002 97.449  1.00 70.59  ? 236 ILE B CG1 1 
ATOM   4611  C CG2 . ILE B 1 236 ? 102.828 125.690 95.553  1.00 70.59  ? 236 ILE B CG2 1 
ATOM   4612  C CD1 . ILE B 1 236 ? 100.164 124.506 96.649  1.00 70.59  ? 236 ILE B CD1 1 
ATOM   4613  N N   . LEU B 1 237 ? 105.244 122.914 96.038  1.00 75.10  ? 237 LEU B N   1 
ATOM   4614  C CA  . LEU B 1 237 ? 106.426 122.577 95.254  1.00 75.10  ? 237 LEU B CA  1 
ATOM   4615  C C   . LEU B 1 237 ? 106.244 121.245 94.534  1.00 75.10  ? 237 LEU B C   1 
ATOM   4616  O O   . LEU B 1 237 ? 106.622 121.102 93.365  1.00 75.10  ? 237 LEU B O   1 
ATOM   4617  C CB  . LEU B 1 237 ? 107.650 122.554 96.171  1.00 75.10  ? 237 LEU B CB  1 
ATOM   4618  C CG  . LEU B 1 237 ? 109.045 122.280 95.614  1.00 75.10  ? 237 LEU B CG  1 
ATOM   4619  C CD1 . LEU B 1 237 ? 110.065 123.149 96.315  1.00 75.10  ? 237 LEU B CD1 1 
ATOM   4620  C CD2 . LEU B 1 237 ? 109.395 120.831 95.828  1.00 75.10  ? 237 LEU B CD2 1 
ATOM   4621  N N   . SER B 1 238 ? 105.655 120.262 95.217  1.00 73.97  ? 238 SER B N   1 
ATOM   4622  C CA  . SER B 1 238 ? 105.354 118.984 94.576  1.00 73.97  ? 238 SER B CA  1 
ATOM   4623  C C   . SER B 1 238 ? 104.352 119.158 93.439  1.00 73.97  ? 238 SER B C   1 
ATOM   4624  O O   . SER B 1 238 ? 104.446 118.486 92.407  1.00 73.97  ? 238 SER B O   1 
ATOM   4625  C CB  . SER B 1 238 ? 104.820 117.992 95.606  1.00 73.97  ? 238 SER B CB  1 
ATOM   4626  O OG  . SER B 1 238 ? 103.443 118.215 95.849  1.00 73.97  ? 238 SER B OG  1 
ATOM   4627  N N   . TRP B 1 239 ? 103.370 120.040 93.626  1.00 80.15  ? 239 TRP B N   1 
ATOM   4628  C CA  . TRP B 1 239 ? 102.418 120.366 92.566  1.00 80.15  ? 239 TRP B CA  1 
ATOM   4629  C C   . TRP B 1 239 ? 103.137 120.884 91.324  1.00 80.15  ? 239 TRP B C   1 
ATOM   4630  O O   . TRP B 1 239 ? 102.910 120.407 90.202  1.00 80.15  ? 239 TRP B O   1 
ATOM   4631  C CB  . TRP B 1 239 ? 101.444 121.422 93.082  1.00 80.15  ? 239 TRP B CB  1 
ATOM   4632  C CG  . TRP B 1 239 ? 100.347 120.906 93.945  1.00 80.15  ? 239 TRP B CG  1 
ATOM   4633  C CD1 . TRP B 1 239 ? 100.371 119.789 94.726  1.00 80.15  ? 239 TRP B CD1 1 
ATOM   4634  C CD2 . TRP B 1 239 ? 99.098  121.551 94.208  1.00 80.15  ? 239 TRP B CD2 1 
ATOM   4635  N NE1 . TRP B 1 239 ? 99.188  119.668 95.414  1.00 80.15  ? 239 TRP B NE1 1 
ATOM   4636  C CE2 . TRP B 1 239 ? 98.392  120.741 95.116  1.00 80.15  ? 239 TRP B CE2 1 
ATOM   4637  C CE3 . TRP B 1 239 ? 98.497  122.726 93.742  1.00 80.15  ? 239 TRP B CE3 1 
ATOM   4638  C CZ2 . TRP B 1 239 ? 97.120  121.068 95.571  1.00 80.15  ? 239 TRP B CZ2 1 
ATOM   4639  C CZ3 . TRP B 1 239 ? 97.232  123.046 94.192  1.00 80.15  ? 239 TRP B CZ3 1 
ATOM   4640  C CH2 . TRP B 1 239 ? 96.558  122.222 95.098  1.00 80.15  ? 239 TRP B CH2 1 
ATOM   4641  N N   . VAL B 1 240 ? 104.012 121.873 91.515  1.00 76.55  ? 240 VAL B N   1 
ATOM   4642  C CA  . VAL B 1 240 ? 104.762 122.436 90.395  1.00 76.55  ? 240 VAL B CA  1 
ATOM   4643  C C   . VAL B 1 240 ? 105.625 121.361 89.747  1.00 76.55  ? 240 VAL B C   1 
ATOM   4644  O O   . VAL B 1 240 ? 105.780 121.321 88.520  1.00 76.55  ? 240 VAL B O   1 
ATOM   4645  C CB  . VAL B 1 240 ? 105.600 123.642 90.863  1.00 76.55  ? 240 VAL B CB  1 
ATOM   4646  C CG1 . VAL B 1 240 ? 106.559 124.088 89.772  1.00 76.55  ? 240 VAL B CG1 1 
ATOM   4647  C CG2 . VAL B 1 240 ? 104.690 124.790 91.274  1.00 76.55  ? 240 VAL B CG2 1 
ATOM   4648  N N   . SER B 1 241 ? 106.187 120.465 90.560  1.00 76.60  ? 241 SER B N   1 
ATOM   4649  C CA  . SER B 1 241 ? 106.939 119.334 90.025  1.00 76.60  ? 241 SER B CA  1 
ATOM   4650  C C   . SER B 1 241 ? 106.054 118.456 89.151  1.00 76.60  ? 241 SER B C   1 
ATOM   4651  O O   . SER B 1 241 ? 106.494 117.946 88.114  1.00 76.60  ? 241 SER B O   1 
ATOM   4652  C CB  . SER B 1 241 ? 107.517 118.514 91.175  1.00 76.60  ? 241 SER B CB  1 
ATOM   4653  O OG  . SER B 1 241 ? 108.051 119.362 92.174  1.00 76.60  ? 241 SER B OG  1 
ATOM   4654  N N   . PHE B 1 242 ? 104.806 118.259 89.573  1.00 81.39  ? 242 PHE B N   1 
ATOM   4655  C CA  . PHE B 1 242 ? 103.852 117.483 88.790  1.00 81.39  ? 242 PHE B CA  1 
ATOM   4656  C C   . PHE B 1 242 ? 103.582 118.143 87.444  1.00 81.39  ? 242 PHE B C   1 
ATOM   4657  O O   . PHE B 1 242 ? 103.473 117.459 86.419  1.00 81.39  ? 242 PHE B O   1 
ATOM   4658  C CB  . PHE B 1 242 ? 102.553 117.322 89.579  1.00 81.39  ? 242 PHE B CB  1 
ATOM   4659  C CG  . PHE B 1 242 ? 101.794 116.066 89.268  1.00 81.39  ? 242 PHE B CG  1 
ATOM   4660  C CD1 . PHE B 1 242 ? 101.947 115.423 88.054  1.00 81.39  ? 242 PHE B CD1 1 
ATOM   4661  C CD2 . PHE B 1 242 ? 100.919 115.532 90.195  1.00 81.39  ? 242 PHE B CD2 1 
ATOM   4662  C CE1 . PHE B 1 242 ? 101.246 114.274 87.772  1.00 81.39  ? 242 PHE B CE1 1 
ATOM   4663  C CE2 . PHE B 1 242 ? 100.216 114.382 89.919  1.00 81.39  ? 242 PHE B CE2 1 
ATOM   4664  C CZ  . PHE B 1 242 ? 100.380 113.754 88.706  1.00 81.39  ? 242 PHE B CZ  1 
ATOM   4665  N N   . TRP B 1 243 ? 103.477 119.473 87.425  1.00 81.68  ? 243 TRP B N   1 
ATOM   4666  C CA  . TRP B 1 243 ? 103.127 120.164 86.186  1.00 81.68  ? 243 TRP B CA  1 
ATOM   4667  C C   . TRP B 1 243 ? 104.161 119.970 85.080  1.00 81.68  ? 243 TRP B C   1 
ATOM   4668  O O   . TRP B 1 243 ? 103.846 120.206 83.909  1.00 81.68  ? 243 TRP B O   1 
ATOM   4669  C CB  . TRP B 1 243 ? 102.933 121.656 86.450  1.00 81.68  ? 243 TRP B CB  1 
ATOM   4670  C CG  . TRP B 1 243 ? 101.497 122.066 86.512  1.00 81.68  ? 243 TRP B CG  1 
ATOM   4671  C CD1 . TRP B 1 243 ? 100.420 121.251 86.702  1.00 81.68  ? 243 TRP B CD1 1 
ATOM   4672  C CD2 . TRP B 1 243 ? 100.978 123.393 86.377  1.00 81.68  ? 243 TRP B CD2 1 
ATOM   4673  N NE1 . TRP B 1 243 ? 99.262  121.989 86.698  1.00 81.68  ? 243 TRP B NE1 1 
ATOM   4674  C CE2 . TRP B 1 243 ? 99.578  123.308 86.500  1.00 81.68  ? 243 TRP B CE2 1 
ATOM   4675  C CE3 . TRP B 1 243 ? 101.562 124.645 86.166  1.00 81.68  ? 243 TRP B CE3 1 
ATOM   4676  C CZ2 . TRP B 1 243 ? 98.753  124.427 86.418  1.00 81.68  ? 243 TRP B CZ2 1 
ATOM   4677  C CZ3 . TRP B 1 243 ? 100.742 125.754 86.085  1.00 81.68  ? 243 TRP B CZ3 1 
ATOM   4678  C CH2 . TRP B 1 243 ? 99.353  125.638 86.211  1.00 81.68  ? 243 TRP B CH2 1 
ATOM   4679  N N   . ILE B 1 244 ? 105.377 119.547 85.415  1.00 83.75  ? 244 ILE B N   1 
ATOM   4680  C CA  . ILE B 1 244 ? 106.430 119.364 84.421  1.00 83.75  ? 244 ILE B CA  1 
ATOM   4681  C C   . ILE B 1 244 ? 106.215 118.050 83.683  1.00 83.75  ? 244 ILE B C   1 
ATOM   4682  O O   . ILE B 1 244 ? 105.844 117.034 84.283  1.00 83.75  ? 244 ILE B O   1 
ATOM   4683  C CB  . ILE B 1 244 ? 107.815 119.410 85.092  1.00 83.75  ? 244 ILE B CB  1 
ATOM   4684  C CG1 . ILE B 1 244 ? 108.020 120.749 85.800  1.00 83.75  ? 244 ILE B CG1 1 
ATOM   4685  C CG2 . ILE B 1 244 ? 108.918 119.181 84.072  1.00 83.75  ? 244 ILE B CG2 1 
ATOM   4686  C CD1 . ILE B 1 244 ? 109.307 120.826 86.586  1.00 83.75  ? 244 ILE B CD1 1 
ATOM   4687  N N   . ASN B 1 245 ? 106.443 118.068 82.370  1.00 95.37  ? 245 ASN B N   1 
ATOM   4688  C CA  . ASN B 1 245 ? 106.278 116.874 81.556  1.00 95.37  ? 245 ASN B CA  1 
ATOM   4689  C C   . ASN B 1 245 ? 107.377 115.855 81.853  1.00 95.37  ? 245 ASN B C   1 
ATOM   4690  O O   . ASN B 1 245 ? 108.447 116.183 82.373  1.00 95.37  ? 245 ASN B O   1 
ATOM   4691  C CB  . ASN B 1 245 ? 106.282 117.228 80.069  1.00 95.37  ? 245 ASN B CB  1 
ATOM   4692  C CG  . ASN B 1 245 ? 107.661 117.591 79.560  1.00 95.37  ? 245 ASN B CG  1 
ATOM   4693  O OD1 . ASN B 1 245 ? 108.440 118.243 80.253  1.00 95.37  ? 245 ASN B OD1 1 
ATOM   4694  N ND2 . ASN B 1 245 ? 107.972 117.165 78.342  1.00 95.37  ? 245 ASN B ND2 1 
ATOM   4695  N N   . MET B 1 246 ? 107.101 114.601 81.488  1.00 101.38 ? 246 MET B N   1 
ATOM   4696  C CA  . MET B 1 246 ? 107.973 113.487 81.847  1.00 101.38 ? 246 MET B CA  1 
ATOM   4697  C C   . MET B 1 246 ? 109.307 113.512 81.114  1.00 101.38 ? 246 MET B C   1 
ATOM   4698  O O   . MET B 1 246 ? 110.243 112.828 81.543  1.00 101.38 ? 246 MET B O   1 
ATOM   4699  C CB  . MET B 1 246 ? 107.257 112.167 81.569  1.00 101.38 ? 246 MET B CB  1 
ATOM   4700  C CG  . MET B 1 246 ? 107.110 111.856 80.093  1.00 101.38 ? 246 MET B CG  1 
ATOM   4701  S SD  . MET B 1 246 ? 105.659 112.654 79.384  1.00 101.38 ? 246 MET B SD  1 
ATOM   4702  C CE  . MET B 1 246 ? 104.343 111.680 80.101  1.00 101.38 ? 246 MET B CE  1 
ATOM   4703  N N   . ASP B 1 247 ? 109.420 114.271 80.021  1.00 102.20 ? 247 ASP B N   1 
ATOM   4704  C CA  . ASP B 1 247 ? 110.691 114.331 79.307  1.00 102.20 ? 247 ASP B CA  1 
ATOM   4705  C C   . ASP B 1 247 ? 111.775 114.990 80.149  1.00 102.20 ? 247 ASP B C   1 
ATOM   4706  O O   . ASP B 1 247 ? 112.962 114.692 79.973  1.00 102.20 ? 247 ASP B O   1 
ATOM   4707  C CB  . ASP B 1 247 ? 110.517 115.069 77.980  1.00 102.20 ? 247 ASP B CB  1 
ATOM   4708  C CG  . ASP B 1 247 ? 110.525 114.130 76.790  1.00 102.20 ? 247 ASP B CG  1 
ATOM   4709  O OD1 . ASP B 1 247 ? 110.066 112.978 76.939  1.00 102.20 ? 247 ASP B OD1 1 
ATOM   4710  O OD2 . ASP B 1 247 ? 110.991 114.542 75.707  1.00 102.20 ? 247 ASP B OD2 1 
ATOM   4711  N N   . ALA B 1 248 ? 111.394 115.878 81.064  1.00 96.01  ? 248 ALA B N   1 
ATOM   4712  C CA  . ALA B 1 248 ? 112.334 116.449 82.027  1.00 96.01  ? 248 ALA B CA  1 
ATOM   4713  C C   . ALA B 1 248 ? 112.386 115.576 83.281  1.00 96.01  ? 248 ALA B C   1 
ATOM   4714  O O   . ALA B 1 248 ? 112.081 116.001 84.395  1.00 96.01  ? 248 ALA B O   1 
ATOM   4715  C CB  . ALA B 1 248 ? 111.948 117.885 82.359  1.00 96.01  ? 248 ALA B CB  1 
ATOM   4716  N N   . ALA B 1 249 ? 112.779 114.321 83.065  1.00 97.65  ? 249 ALA B N   1 
ATOM   4717  C CA  . ALA B 1 249 ? 112.781 113.340 84.148  1.00 97.65  ? 249 ALA B CA  1 
ATOM   4718  C C   . ALA B 1 249 ? 113.690 113.721 85.311  1.00 97.65  ? 249 ALA B C   1 
ATOM   4719  O O   . ALA B 1 249 ? 113.247 113.604 86.469  1.00 97.65  ? 249 ALA B O   1 
ATOM   4720  C CB  . ALA B 1 249 ? 113.144 111.960 83.588  1.00 97.65  ? 249 ALA B CB  1 
ATOM   4721  N N   . PRO B 1 250 ? 114.947 114.146 85.106  1.00 93.82  ? 250 PRO B N   1 
ATOM   4722  C CA  . PRO B 1 250 ? 115.782 114.488 86.272  1.00 93.82  ? 250 PRO B CA  1 
ATOM   4723  C C   . PRO B 1 250 ? 115.191 115.584 87.143  1.00 93.82  ? 250 PRO B C   1 
ATOM   4724  O O   . PRO B 1 250 ? 115.267 115.499 88.375  1.00 93.82  ? 250 PRO B O   1 
ATOM   4725  C CB  . PRO B 1 250 ? 117.114 114.919 85.638  1.00 93.82  ? 250 PRO B CB  1 
ATOM   4726  C CG  . PRO B 1 250 ? 116.785 115.242 84.222  1.00 93.82  ? 250 PRO B CG  1 
ATOM   4727  C CD  . PRO B 1 250 ? 115.706 114.286 83.849  1.00 93.82  ? 250 PRO B CD  1 
ATOM   4728  N N   . ALA B 1 251 ? 114.582 116.603 86.534  1.00 92.11  ? 251 ALA B N   1 
ATOM   4729  C CA  . ALA B 1 251 ? 114.003 117.691 87.316  1.00 92.11  ? 251 ALA B CA  1 
ATOM   4730  C C   . ALA B 1 251 ? 112.872 117.187 88.202  1.00 92.11  ? 251 ALA B C   1 
ATOM   4731  O O   . ALA B 1 251 ? 112.846 117.455 89.410  1.00 92.11  ? 251 ALA B O   1 
ATOM   4732  C CB  . ALA B 1 251 ? 113.509 118.798 86.386  1.00 92.11  ? 251 ALA B CB  1 
ATOM   4733  N N   . ARG B 1 252 ? 111.932 116.441 87.617  1.00 90.34  ? 252 ARG B N   1 
ATOM   4734  C CA  . ARG B 1 252 ? 110.811 115.925 88.395  1.00 90.34  ? 252 ARG B CA  1 
ATOM   4735  C C   . ARG B 1 252 ? 111.285 114.979 89.487  1.00 90.34  ? 252 ARG B C   1 
ATOM   4736  O O   . ARG B 1 252 ? 110.798 115.039 90.622  1.00 90.34  ? 252 ARG B O   1 
ATOM   4737  C CB  . ARG B 1 252 ? 109.812 115.218 87.481  1.00 90.34  ? 252 ARG B CB  1 
ATOM   4738  C CG  . ARG B 1 252 ? 109.090 116.135 86.520  1.00 90.34  ? 252 ARG B CG  1 
ATOM   4739  C CD  . ARG B 1 252 ? 108.418 115.335 85.421  1.00 90.34  ? 252 ARG B CD  1 
ATOM   4740  N NE  . ARG B 1 252 ? 107.730 114.163 85.949  1.00 90.34  ? 252 ARG B NE  1 
ATOM   4741  C CZ  . ARG B 1 252 ? 106.430 114.112 86.202  1.00 90.34  ? 252 ARG B CZ  1 
ATOM   4742  N NH1 . ARG B 1 252 ? 105.640 115.146 85.969  1.00 90.34  ? 252 ARG B NH1 1 
ATOM   4743  N NH2 . ARG B 1 252 ? 105.910 112.993 86.699  1.00 90.34  ? 252 ARG B NH2 1 
ATOM   4744  N N   . VAL B 1 253 ? 112.237 114.098 89.169  1.00 86.39  ? 253 VAL B N   1 
ATOM   4745  C CA  . VAL B 1 253 ? 112.675 113.132 90.171  1.00 86.39  ? 253 VAL B CA  1 
ATOM   4746  C C   . VAL B 1 253 ? 113.381 113.837 91.326  1.00 86.39  ? 253 VAL B C   1 
ATOM   4747  O O   . VAL B 1 253 ? 113.122 113.534 92.496  1.00 86.39  ? 253 VAL B O   1 
ATOM   4748  C CB  . VAL B 1 253 ? 113.537 112.022 89.532  1.00 86.39  ? 253 VAL B CB  1 
ATOM   4749  C CG1 . VAL B 1 253 ? 114.924 112.508 89.157  1.00 86.39  ? 253 VAL B CG1 1 
ATOM   4750  C CG2 . VAL B 1 253 ? 113.624 110.821 90.462  1.00 86.39  ? 253 VAL B CG2 1 
ATOM   4751  N N   . ALA B 1 254 ? 114.234 114.824 91.029  1.00 86.69  ? 254 ALA B N   1 
ATOM   4752  C CA  . ALA B 1 254 ? 114.931 115.534 92.096  1.00 86.69  ? 254 ALA B CA  1 
ATOM   4753  C C   . ALA B 1 254 ? 113.964 116.363 92.934  1.00 86.69  ? 254 ALA B C   1 
ATOM   4754  O O   . ALA B 1 254 ? 114.135 116.491 94.154  1.00 86.69  ? 254 ALA B O   1 
ATOM   4755  C CB  . ALA B 1 254 ? 116.025 116.414 91.507  1.00 86.69  ? 254 ALA B CB  1 
ATOM   4756  N N   . LEU B 1 255 ? 112.945 116.941 92.296  1.00 81.58  ? 255 LEU B N   1 
ATOM   4757  C CA  . LEU B 1 255 ? 111.916 117.646 93.049  1.00 81.58  ? 255 LEU B CA  1 
ATOM   4758  C C   . LEU B 1 255 ? 111.176 116.684 93.976  1.00 81.58  ? 255 LEU B C   1 
ATOM   4759  O O   . LEU B 1 255 ? 110.841 117.030 95.120  1.00 81.58  ? 255 LEU B O   1 
ATOM   4760  C CB  . LEU B 1 255 ? 110.961 118.341 92.081  1.00 81.58  ? 255 LEU B CB  1 
ATOM   4761  C CG  . LEU B 1 255 ? 111.265 119.776 91.620  1.00 81.58  ? 255 LEU B CG  1 
ATOM   4762  C CD1 . LEU B 1 255 ? 110.815 120.808 92.629  1.00 81.58  ? 255 LEU B CD1 1 
ATOM   4763  C CD2 . LEU B 1 255 ? 112.745 119.969 91.315  1.00 81.58  ? 255 LEU B CD2 1 
ATOM   4764  N N   . GLY B 1 256 ? 110.928 115.461 93.506  1.00 81.71  ? 256 GLY B N   1 
ATOM   4765  C CA  . GLY B 1 256 ? 110.356 114.451 94.381  1.00 81.71  ? 256 GLY B CA  1 
ATOM   4766  C C   . GLY B 1 256 ? 111.244 114.144 95.574  1.00 81.71  ? 256 GLY B C   1 
ATOM   4767  O O   . GLY B 1 256 ? 110.762 114.021 96.705  1.00 81.71  ? 256 GLY B O   1 
ATOM   4768  N N   . ILE B 1 257 ? 112.554 114.027 95.343  1.00 81.87  ? 257 ILE B N   1 
ATOM   4769  C CA  . ILE B 1 257 ? 113.468 113.768 96.458  1.00 81.87  ? 257 ILE B CA  1 
ATOM   4770  C C   . ILE B 1 257 ? 113.423 114.903 97.473  1.00 81.87  ? 257 ILE B C   1 
ATOM   4771  O O   . ILE B 1 257 ? 113.379 114.662 98.685  1.00 81.87  ? 257 ILE B O   1 
ATOM   4772  C CB  . ILE B 1 257 ? 114.909 113.515 95.977  1.00 81.87  ? 257 ILE B CB  1 
ATOM   4773  C CG1 . ILE B 1 257 ? 114.958 112.884 94.595  1.00 81.87  ? 257 ILE B CG1 1 
ATOM   4774  C CG2 . ILE B 1 257 ? 115.668 112.683 96.992  1.00 81.87  ? 257 ILE B CG2 1 
ATOM   4775  C CD1 . ILE B 1 257 ? 116.352 112.659 94.066  1.00 81.87  ? 257 ILE B CD1 1 
ATOM   4776  N N   . THR B 1 258 ? 113.464 116.154 97.007  1.00 77.57  ? 258 THR B N   1 
ATOM   4777  C CA  . THR B 1 258 ? 113.492 117.242 97.982  1.00 77.57  ? 258 THR B CA  1 
ATOM   4778  C C   . THR B 1 258 ? 112.188 117.300 98.767  1.00 77.57  ? 258 THR B C   1 
ATOM   4779  O O   . THR B 1 258 ? 112.205 117.563 99.976  1.00 77.57  ? 258 THR B O   1 
ATOM   4780  C CB  . THR B 1 258 ? 113.802 118.594 97.330  1.00 77.57  ? 258 THR B CB  1 
ATOM   4781  O OG1 . THR B 1 258 ? 113.597 119.638 98.289  1.00 77.57  ? 258 THR B OG1 1 
ATOM   4782  C CG2 . THR B 1 258 ? 112.928 118.866 96.149  1.00 77.57  ? 258 THR B CG2 1 
ATOM   4783  N N   . THR B 1 259 ? 111.053 117.023 98.114  1.00 75.13  ? 259 THR B N   1 
ATOM   4784  C CA  . THR B 1 259 ? 109.800 116.905 98.857  1.00 75.13  ? 259 THR B CA  1 
ATOM   4785  C C   . THR B 1 259 ? 109.901 115.835 99.939  1.00 75.13  ? 259 THR B C   1 
ATOM   4786  O O   . THR B 1 259 ? 109.552 116.074 101.104 1.00 75.13  ? 259 THR B O   1 
ATOM   4787  C CB  . THR B 1 259 ? 108.644 116.579 97.911  1.00 75.13  ? 259 THR B CB  1 
ATOM   4788  O OG1 . THR B 1 259 ? 108.962 115.408 97.149  1.00 75.13  ? 259 THR B OG1 1 
ATOM   4789  C CG2 . THR B 1 259 ? 108.360 117.733 96.977  1.00 75.13  ? 259 THR B CG2 1 
ATOM   4790  N N   . VAL B 1 260 ? 110.387 114.647 99.568  1.00 73.62  ? 260 VAL B N   1 
ATOM   4791  C CA  . VAL B 1 260 ? 110.438 113.531 100.512 1.00 73.62  ? 260 VAL B CA  1 
ATOM   4792  C C   . VAL B 1 260 ? 111.302 113.888 101.715 1.00 73.62  ? 260 VAL B C   1 
ATOM   4793  O O   . VAL B 1 260 ? 110.915 113.671 102.871 1.00 73.62  ? 260 VAL B O   1 
ATOM   4794  C CB  . VAL B 1 260 ? 110.955 112.261 99.812  1.00 73.62  ? 260 VAL B CB  1 
ATOM   4795  C CG1 . VAL B 1 260 ? 111.396 111.228 100.839 1.00 73.62  ? 260 VAL B CG1 1 
ATOM   4796  C CG2 . VAL B 1 260 ? 109.896 111.684 98.889  1.00 73.62  ? 260 VAL B CG2 1 
ATOM   4797  N N   . LEU B 1 261 ? 112.485 114.446 101.459 1.00 73.34  ? 261 LEU B N   1 
ATOM   4798  C CA  . LEU B 1 261 ? 113.415 114.713 102.551 1.00 73.34  ? 261 LEU B CA  1 
ATOM   4799  C C   . LEU B 1 261 ? 112.933 115.858 103.436 1.00 73.34  ? 261 LEU B C   1 
ATOM   4800  O O   . LEU B 1 261 ? 113.052 115.782 104.666 1.00 73.34  ? 261 LEU B O   1 
ATOM   4801  C CB  . LEU B 1 261 ? 114.818 114.974 102.005 1.00 73.34  ? 261 LEU B CB  1 
ATOM   4802  C CG  . LEU B 1 261 ? 115.263 113.978 100.932 1.00 73.34  ? 261 LEU B CG  1 
ATOM   4803  C CD1 . LEU B 1 261 ? 116.661 114.272 100.423 1.00 73.34  ? 261 LEU B CD1 1 
ATOM   4804  C CD2 . LEU B 1 261 ? 115.184 112.558 101.471 1.00 73.34  ? 261 LEU B CD2 1 
ATOM   4805  N N   . THR B 1 262 ? 112.367 116.916 102.847 1.00 70.14  ? 262 THR B N   1 
ATOM   4806  C CA  . THR B 1 262 ? 111.793 117.969 103.678 1.00 70.14  ? 262 THR B CA  1 
ATOM   4807  C C   . THR B 1 262 ? 110.696 117.413 104.576 1.00 70.14  ? 262 THR B C   1 
ATOM   4808  O O   . THR B 1 262 ? 110.649 117.715 105.778 1.00 70.14  ? 262 THR B O   1 
ATOM   4809  C CB  . THR B 1 262 ? 111.246 119.097 102.806 1.00 70.14  ? 262 THR B CB  1 
ATOM   4810  O OG1 . THR B 1 262 ? 110.425 118.547 101.769 1.00 70.14  ? 262 THR B OG1 1 
ATOM   4811  C CG2 . THR B 1 262 ? 112.382 119.889 102.184 1.00 70.14  ? 262 THR B CG2 1 
ATOM   4812  N N   . MET B 1 263 ? 109.821 116.572 104.017 1.00 67.27  ? 263 MET B N   1 
ATOM   4813  C CA  . MET B 1 263 ? 108.730 116.024 104.812 1.00 67.27  ? 263 MET B CA  1 
ATOM   4814  C C   . MET B 1 263 ? 109.247 115.138 105.938 1.00 67.27  ? 263 MET B C   1 
ATOM   4815  O O   . MET B 1 263 ? 108.732 115.194 107.059 1.00 67.27  ? 263 MET B O   1 
ATOM   4816  C CB  . MET B 1 263 ? 107.760 115.252 103.921 1.00 67.27  ? 263 MET B CB  1 
ATOM   4817  C CG  . MET B 1 263 ? 106.315 115.327 104.387 1.00 67.27  ? 263 MET B CG  1 
ATOM   4818  S SD  . MET B 1 263 ? 105.525 116.897 103.986 1.00 67.27  ? 263 MET B SD  1 
ATOM   4819  C CE  . MET B 1 263 ? 105.616 117.739 105.563 1.00 67.27  ? 263 MET B CE  1 
ATOM   4820  N N   . THR B 1 264 ? 110.262 114.311 105.669 1.00 71.23  ? 264 THR B N   1 
ATOM   4821  C CA  . THR B 1 264 ? 110.725 113.414 106.726 1.00 71.23  ? 264 THR B CA  1 
ATOM   4822  C C   . THR B 1 264 ? 111.467 114.178 107.819 1.00 71.23  ? 264 THR B C   1 
ATOM   4823  O O   . THR B 1 264 ? 111.362 113.826 109.000 1.00 71.23  ? 264 THR B O   1 
ATOM   4824  C CB  . THR B 1 264 ? 111.594 112.284 106.168 1.00 71.23  ? 264 THR B CB  1 
ATOM   4825  O OG1 . THR B 1 264 ? 112.109 111.504 107.254 1.00 71.23  ? 264 THR B OG1 1 
ATOM   4826  C CG2 . THR B 1 264 ? 112.759 112.823 105.388 1.00 71.23  ? 264 THR B CG2 1 
ATOM   4827  N N   . THR B 1 265 ? 112.212 115.232 107.462 1.00 69.89  ? 265 THR B N   1 
ATOM   4828  C CA  . THR B 1 265 ? 112.814 116.059 108.509 1.00 69.89  ? 265 THR B CA  1 
ATOM   4829  C C   . THR B 1 265 ? 111.749 116.743 109.358 1.00 69.89  ? 265 THR B C   1 
ATOM   4830  O O   . THR B 1 265 ? 111.873 116.804 110.591 1.00 69.89  ? 265 THR B O   1 
ATOM   4831  C CB  . THR B 1 265 ? 113.771 117.095 107.915 1.00 69.89  ? 265 THR B CB  1 
ATOM   4832  O OG1 . THR B 1 265 ? 113.029 118.110 107.224 1.00 69.89  ? 265 THR B OG1 1 
ATOM   4833  C CG2 . THR B 1 265 ? 114.797 116.446 106.999 1.00 69.89  ? 265 THR B CG2 1 
ATOM   4834  N N   . GLN B 1 266 ? 110.695 117.264 108.723 1.00 67.93  ? 266 GLN B N   1 
ATOM   4835  C CA  . GLN B 1 266 ? 109.617 117.876 109.496 1.00 67.93  ? 266 GLN B CA  1 
ATOM   4836  C C   . GLN B 1 266 ? 108.955 116.856 110.416 1.00 67.93  ? 266 GLN B C   1 
ATOM   4837  O O   . GLN B 1 266 ? 108.635 117.164 111.571 1.00 67.93  ? 266 GLN B O   1 
ATOM   4838  C CB  . GLN B 1 266 ? 108.591 118.508 108.557 1.00 67.93  ? 266 GLN B CB  1 
ATOM   4839  C CG  . GLN B 1 266 ? 109.064 119.727 107.743 1.00 67.93  ? 266 GLN B CG  1 
ATOM   4840  C CD  . GLN B 1 266 ? 109.825 120.781 108.545 1.00 67.93  ? 266 GLN B CD  1 
ATOM   4841  O OE1 . GLN B 1 266 ? 110.873 120.515 109.135 1.00 67.93  ? 266 GLN B OE1 1 
ATOM   4842  N NE2 . GLN B 1 266 ? 109.289 121.996 108.560 1.00 67.93  ? 266 GLN B NE2 1 
ATOM   4843  N N   . SER B 1 267 ? 108.746 115.634 109.918 1.00 70.36  ? 267 SER B N   1 
ATOM   4844  C CA  . SER B 1 267 ? 108.160 114.581 110.743 1.00 70.36  ? 267 SER B CA  1 
ATOM   4845  C C   . SER B 1 267 ? 109.049 114.252 111.932 1.00 70.36  ? 267 SER B C   1 
ATOM   4846  O O   . SER B 1 267 ? 108.559 114.079 113.055 1.00 70.36  ? 267 SER B O   1 
ATOM   4847  C CB  . SER B 1 267 ? 107.918 113.329 109.901 1.00 70.36  ? 267 SER B CB  1 
ATOM   4848  O OG  . SER B 1 267 ? 106.735 113.440 109.135 1.00 70.36  ? 267 SER B OG  1 
ATOM   4849  N N   . SER B 1 268 ? 110.360 114.152 111.702 1.00 71.08  ? 268 SER B N   1 
ATOM   4850  C CA  . SER B 1 268 ? 111.283 113.858 112.791 1.00 71.08  ? 268 SER B CA  1 
ATOM   4851  C C   . SER B 1 268 ? 111.226 114.945 113.855 1.00 71.08  ? 268 SER B C   1 
ATOM   4852  O O   . SER B 1 268 ? 111.164 114.654 115.055 1.00 71.08  ? 268 SER B O   1 
ATOM   4853  C CB  . SER B 1 268 ? 112.703 113.708 112.247 1.00 71.08  ? 268 SER B CB  1 
ATOM   4854  O OG  . SER B 1 268 ? 113.137 114.904 111.621 1.00 71.08  ? 268 SER B OG  1 
ATOM   4855  N N   . GLY B 1 269 ? 111.226 116.210 113.427 1.00 71.45  ? 269 GLY B N   1 
ATOM   4856  C CA  . GLY B 1 269 ? 111.140 117.298 114.389 1.00 71.45  ? 269 GLY B CA  1 
ATOM   4857  C C   . GLY B 1 269 ? 109.853 117.264 115.192 1.00 71.45  ? 269 GLY B C   1 
ATOM   4858  O O   . GLY B 1 269 ? 109.866 117.382 116.424 1.00 71.45  ? 269 GLY B O   1 
ATOM   4859  N N   . SER B 1 270 ? 108.722 117.078 114.504 1.00 67.45  ? 270 SER B N   1 
ATOM   4860  C CA  . SER B 1 270 ? 107.435 117.061 115.192 1.00 67.45  ? 270 SER B CA  1 
ATOM   4861  C C   . SER B 1 270 ? 107.357 115.919 116.195 1.00 67.45  ? 270 SER B C   1 
ATOM   4862  O O   . SER B 1 270 ? 106.896 116.108 117.326 1.00 67.45  ? 270 SER B O   1 
ATOM   4863  C CB  . SER B 1 270 ? 106.296 116.949 114.181 1.00 67.45  ? 270 SER B CB  1 
ATOM   4864  O OG  . SER B 1 270 ? 105.038 116.992 114.832 1.00 67.45  ? 270 SER B OG  1 
ATOM   4865  N N   . ARG B 1 271 ? 107.804 114.726 115.801 1.00 70.60  ? 271 ARG B N   1 
ATOM   4866  C CA  . ARG B 1 271 ? 107.707 113.573 116.685 1.00 70.60  ? 271 ARG B CA  1 
ATOM   4867  C C   . ARG B 1 271 ? 108.729 113.605 117.813 1.00 70.60  ? 271 ARG B C   1 
ATOM   4868  O O   . ARG B 1 271 ? 108.496 112.982 118.855 1.00 70.60  ? 271 ARG B O   1 
ATOM   4869  C CB  . ARG B 1 271 ? 107.852 112.282 115.877 1.00 70.60  ? 271 ARG B CB  1 
ATOM   4870  C CG  . ARG B 1 271 ? 106.639 111.968 115.017 1.00 70.60  ? 271 ARG B CG  1 
ATOM   4871  C CD  . ARG B 1 271 ? 106.726 110.575 114.421 1.00 70.60  ? 271 ARG B CD  1 
ATOM   4872  N NE  . ARG B 1 271 ? 107.821 110.450 113.465 1.00 70.60  ? 271 ARG B NE  1 
ATOM   4873  C CZ  . ARG B 1 271 ? 107.691 110.598 112.154 1.00 70.60  ? 271 ARG B CZ  1 
ATOM   4874  N NH1 . ARG B 1 271 ? 106.522 110.877 111.602 1.00 70.60  ? 271 ARG B NH1 1 
ATOM   4875  N NH2 . ARG B 1 271 ? 108.761 110.458 111.377 1.00 70.60  ? 271 ARG B NH2 1 
ATOM   4876  N N   . ALA B 1 272 ? 109.848 114.309 117.641 1.00 76.81  ? 272 ALA B N   1 
ATOM   4877  C CA  . ALA B 1 272 ? 110.817 114.446 118.717 1.00 76.81  ? 272 ALA B CA  1 
ATOM   4878  C C   . ALA B 1 272 ? 110.542 115.641 119.619 1.00 76.81  ? 272 ALA B C   1 
ATOM   4879  O O   . ALA B 1 272 ? 111.190 115.768 120.663 1.00 76.81  ? 272 ALA B O   1 
ATOM   4880  C CB  . ALA B 1 272 ? 112.234 114.558 118.143 1.00 76.81  ? 272 ALA B CB  1 
ATOM   4881  N N   . SER B 1 273 ? 109.605 116.512 119.250 1.00 74.50  ? 273 SER B N   1 
ATOM   4882  C CA  . SER B 1 273 ? 109.303 117.692 120.051 1.00 74.50  ? 273 SER B CA  1 
ATOM   4883  C C   . SER B 1 273 ? 108.318 117.428 121.187 1.00 74.50  ? 273 SER B C   1 
ATOM   4884  O O   . SER B 1 273 ? 108.065 118.338 121.984 1.00 74.50  ? 273 SER B O   1 
ATOM   4885  C CB  . SER B 1 273 ? 108.753 118.802 119.152 1.00 74.50  ? 273 SER B CB  1 
ATOM   4886  O OG  . SER B 1 273 ? 107.588 118.369 118.470 1.00 74.50  ? 273 SER B OG  1 
ATOM   4887  N N   . LEU B 1 274 ? 107.768 116.222 121.296 1.00 71.26  ? 274 LEU B N   1 
ATOM   4888  C CA  . LEU B 1 274 ? 106.681 115.959 122.227 1.00 71.26  ? 274 LEU B CA  1 
ATOM   4889  C C   . LEU B 1 274 ? 106.964 114.710 123.050 1.00 71.26  ? 274 LEU B C   1 
ATOM   4890  O O   . LEU B 1 274 ? 107.724 113.838 122.618 1.00 71.26  ? 274 LEU B O   1 
ATOM   4891  C CB  . LEU B 1 274 ? 105.357 115.789 121.466 1.00 71.26  ? 274 LEU B CB  1 
ATOM   4892  C CG  . LEU B 1 274 ? 104.135 116.517 122.023 1.00 71.26  ? 274 LEU B CG  1 
ATOM   4893  C CD1 . LEU B 1 274 ? 104.514 117.923 122.452 1.00 71.26  ? 274 LEU B CD1 1 
ATOM   4894  C CD2 . LEU B 1 274 ? 103.023 116.551 120.997 1.00 71.26  ? 274 LEU B CD2 1 
ATOM   4895  N N   . PRO B 1 275 ? 106.376 114.600 124.241 1.00 64.92  ? 275 PRO B N   1 
ATOM   4896  C CA  . PRO B 1 275 ? 106.569 113.392 125.051 1.00 64.92  ? 275 PRO B CA  1 
ATOM   4897  C C   . PRO B 1 275 ? 105.932 112.166 124.415 1.00 64.92  ? 275 PRO B C   1 
ATOM   4898  O O   . PRO B 1 275 ? 105.002 112.252 123.611 1.00 64.92  ? 275 PRO B O   1 
ATOM   4899  C CB  . PRO B 1 275 ? 105.885 113.740 126.378 1.00 64.92  ? 275 PRO B CB  1 
ATOM   4900  C CG  . PRO B 1 275 ? 104.936 114.831 126.036 1.00 64.92  ? 275 PRO B CG  1 
ATOM   4901  C CD  . PRO B 1 275 ? 105.643 115.631 124.991 1.00 64.92  ? 275 PRO B CD  1 
ATOM   4902  N N   . LYS B 1 276 ? 106.454 111.004 124.803 1.00 67.50  ? 276 LYS B N   1 
ATOM   4903  C CA  . LYS B 1 276 ? 105.993 109.736 124.251 1.00 67.50  ? 276 LYS B CA  1 
ATOM   4904  C C   . LYS B 1 276 ? 104.573 109.447 124.722 1.00 67.50  ? 276 LYS B C   1 
ATOM   4905  O O   . LYS B 1 276 ? 104.327 109.306 125.924 1.00 67.50  ? 276 LYS B O   1 
ATOM   4906  C CB  . LYS B 1 276 ? 106.933 108.608 124.671 1.00 67.50  ? 276 LYS B CB  1 
ATOM   4907  C CG  . LYS B 1 276 ? 108.344 109.056 125.030 1.00 67.50  ? 276 LYS B CG  1 
ATOM   4908  C CD  . LYS B 1 276 ? 109.159 109.401 123.796 1.00 67.50  ? 276 LYS B CD  1 
ATOM   4909  C CE  . LYS B 1 276 ? 110.535 109.926 124.175 1.00 67.50  ? 276 LYS B CE  1 
ATOM   4910  N NZ  . LYS B 1 276 ? 111.318 108.929 124.954 1.00 67.50  ? 276 LYS B NZ  1 
ATOM   4911  N N   . VAL B 1 277 ? 103.639 109.357 123.779 1.00 59.38  ? 277 VAL B N   1 
ATOM   4912  C CA  . VAL B 1 277 ? 102.241 109.074 124.076 1.00 59.38  ? 277 VAL B CA  1 
ATOM   4913  C C   . VAL B 1 277 ? 101.734 108.041 123.079 1.00 59.38  ? 277 VAL B C   1 
ATOM   4914  O O   . VAL B 1 277 ? 102.040 108.118 121.884 1.00 59.38  ? 277 VAL B O   1 
ATOM   4915  C CB  . VAL B 1 277 ? 101.378 110.352 124.028 1.00 59.38  ? 277 VAL B CB  1 
ATOM   4916  C CG1 . VAL B 1 277 ? 99.911  109.997 124.070 1.00 59.38  ? 277 VAL B CG1 1 
ATOM   4917  C CG2 . VAL B 1 277 ? 101.732 111.279 125.178 1.00 59.38  ? 277 VAL B CG2 1 
ATOM   4918  N N   . SER B 1 278 ? 100.956 107.074 123.572 1.00 58.35  ? 278 SER B N   1 
ATOM   4919  C CA  . SER B 1 278 ? 100.526 105.961 122.731 1.00 58.35  ? 278 SER B CA  1 
ATOM   4920  C C   . SER B 1 278 ? 99.617  106.422 121.595 1.00 58.35  ? 278 SER B C   1 
ATOM   4921  O O   . SER B 1 278 ? 99.832  106.056 120.434 1.00 58.35  ? 278 SER B O   1 
ATOM   4922  C CB  . SER B 1 278 ? 99.823  104.905 123.581 1.00 58.35  ? 278 SER B CB  1 
ATOM   4923  O OG  . SER B 1 278 ? 99.141  103.972 122.762 1.00 58.35  ? 278 SER B OG  1 
ATOM   4924  N N   . TYR B 1 279 ? 98.595  107.218 121.901 1.00 51.01  ? 279 TYR B N   1 
ATOM   4925  C CA  . TYR B 1 279 ? 97.583  107.496 120.892 1.00 51.01  ? 279 TYR B CA  1 
ATOM   4926  C C   . TYR B 1 279 ? 98.068  108.544 119.891 1.00 51.01  ? 279 TYR B C   1 
ATOM   4927  O O   . TYR B 1 279 ? 99.015  109.294 120.141 1.00 51.01  ? 279 TYR B O   1 
ATOM   4928  C CB  . TYR B 1 279 ? 96.266  107.936 121.541 1.00 51.01  ? 279 TYR B CB  1 
ATOM   4929  C CG  . TYR B 1 279 ? 96.348  109.082 122.531 1.00 51.01  ? 279 TYR B CG  1 
ATOM   4930  C CD1 . TYR B 1 279 ? 95.791  108.964 123.795 1.00 51.01  ? 279 TYR B CD1 1 
ATOM   4931  C CD2 . TYR B 1 279 ? 96.917  110.298 122.183 1.00 51.01  ? 279 TYR B CD2 1 
ATOM   4932  C CE1 . TYR B 1 279 ? 95.840  110.004 124.696 1.00 51.01  ? 279 TYR B CE1 1 
ATOM   4933  C CE2 . TYR B 1 279 ? 96.964  111.346 123.076 1.00 51.01  ? 279 TYR B CE2 1 
ATOM   4934  C CZ  . TYR B 1 279 ? 96.430  111.191 124.332 1.00 51.01  ? 279 TYR B CZ  1 
ATOM   4935  O OH  . TYR B 1 279 ? 96.477  112.235 125.225 1.00 51.01  ? 279 TYR B OH  1 
ATOM   4936  N N   . VAL B 1 280 ? 97.397  108.584 118.740 1.00 48.24  ? 280 VAL B N   1 
ATOM   4937  C CA  . VAL B 1 280 ? 97.730  109.535 117.685 1.00 48.24  ? 280 VAL B CA  1 
ATOM   4938  C C   . VAL B 1 280 ? 97.145  110.898 118.016 1.00 48.24  ? 280 VAL B C   1 
ATOM   4939  O O   . VAL B 1 280 ? 96.043  111.017 118.562 1.00 48.24  ? 280 VAL B O   1 
ATOM   4940  C CB  . VAL B 1 280 ? 97.224  109.039 116.318 1.00 48.24  ? 280 VAL B CB  1 
ATOM   4941  C CG1 . VAL B 1 280 ? 98.183  108.029 115.735 1.00 48.24  ? 280 VAL B CG1 1 
ATOM   4942  C CG2 . VAL B 1 280 ? 95.834  108.446 116.456 1.00 48.24  ? 280 VAL B CG2 1 
ATOM   4943  N N   . LYS B 1 281 ? 97.884  111.940 117.659 1.00 48.63  ? 281 LYS B N   1 
ATOM   4944  C CA  . LYS B 1 281 ? 97.458  113.318 117.832 1.00 48.63  ? 281 LYS B CA  1 
ATOM   4945  C C   . LYS B 1 281 ? 97.181  113.942 116.470 1.00 48.63  ? 281 LYS B C   1 
ATOM   4946  O O   . LYS B 1 281 ? 97.531  113.391 115.424 1.00 48.63  ? 281 LYS B O   1 
ATOM   4947  C CB  . LYS B 1 281 ? 98.517  114.119 118.595 1.00 48.63  ? 281 LYS B CB  1 
ATOM   4948  C CG  . LYS B 1 281 ? 99.941  113.771 118.214 1.00 48.63  ? 281 LYS B CG  1 
ATOM   4949  C CD  . LYS B 1 281 ? 100.922 114.210 119.284 1.00 48.63  ? 281 LYS B CD  1 
ATOM   4950  C CE  . LYS B 1 281 ? 100.863 113.307 120.502 1.00 48.63  ? 281 LYS B CE  1 
ATOM   4951  N NZ  . LYS B 1 281 ? 101.415 111.956 120.217 1.00 48.63  ? 281 LYS B NZ  1 
ATOM   4952  N N   . ALA B 1 282 ? 96.535  115.109 116.496 1.00 51.52  ? 282 ALA B N   1 
ATOM   4953  C CA  . ALA B 1 282 ? 96.132  115.755 115.252 1.00 51.52  ? 282 ALA B CA  1 
ATOM   4954  C C   . ALA B 1 282 ? 97.336  116.099 114.387 1.00 51.52  ? 282 ALA B C   1 
ATOM   4955  O O   . ALA B 1 282 ? 97.310  115.893 113.167 1.00 51.52  ? 282 ALA B O   1 
ATOM   4956  C CB  . ALA B 1 282 ? 95.315  117.010 115.553 1.00 51.52  ? 282 ALA B CB  1 
ATOM   4957  N N   . ILE B 1 283 ? 98.402  116.618 114.997 1.00 48.51  ? 283 ILE B N   1 
ATOM   4958  C CA  . ILE B 1 283 ? 99.576  116.999 114.219 1.00 48.51  ? 283 ILE B CA  1 
ATOM   4959  C C   . ILE B 1 283 ? 100.208 115.770 113.580 1.00 48.51  ? 283 ILE B C   1 
ATOM   4960  O O   . ILE B 1 283 ? 100.677 115.820 112.436 1.00 48.51  ? 283 ILE B O   1 
ATOM   4961  C CB  . ILE B 1 283 ? 100.579 117.780 115.092 1.00 48.51  ? 283 ILE B CB  1 
ATOM   4962  C CG1 . ILE B 1 283 ? 101.554 118.563 114.213 1.00 48.51  ? 283 ILE B CG1 1 
ATOM   4963  C CG2 . ILE B 1 283 ? 101.331 116.865 116.047 1.00 48.51  ? 283 ILE B CG2 1 
ATOM   4964  C CD1 . ILE B 1 283 ? 100.952 119.804 113.598 1.00 48.51  ? 283 ILE B CD1 1 
ATOM   4965  N N   . ASP B 1 284 ? 100.200 114.639 114.288 1.00 51.72  ? 284 ASP B N   1 
ATOM   4966  C CA  . ASP B 1 284 ? 100.796 113.430 113.735 1.00 51.72  ? 284 ASP B CA  1 
ATOM   4967  C C   . ASP B 1 284 ? 99.993  112.911 112.551 1.00 51.72  ? 284 ASP B C   1 
ATOM   4968  O O   . ASP B 1 284 ? 100.569 112.535 111.526 1.00 51.72  ? 284 ASP B O   1 
ATOM   4969  C CB  . ASP B 1 284 ? 100.917 112.359 114.815 1.00 51.72  ? 284 ASP B CB  1 
ATOM   4970  C CG  . ASP B 1 284 ? 101.986 111.338 114.497 1.00 51.72  ? 284 ASP B CG  1 
ATOM   4971  O OD1 . ASP B 1 284 ? 101.703 110.404 113.719 1.00 51.72  ? 284 ASP B OD1 1 
ATOM   4972  O OD2 . ASP B 1 284 ? 103.113 111.474 115.018 1.00 51.72  ? 284 ASP B OD2 1 
ATOM   4973  N N   . ILE B 1 285 ? 98.663  112.891 112.667 1.00 49.72  ? 285 ILE B N   1 
ATOM   4974  C CA  . ILE B 1 285 ? 97.824  112.446 111.557 1.00 49.72  ? 285 ILE B CA  1 
ATOM   4975  C C   . ILE B 1 285 ? 98.014  113.361 110.355 1.00 49.72  ? 285 ILE B C   1 
ATOM   4976  O O   . ILE B 1 285 ? 98.178  112.903 109.217 1.00 49.72  ? 285 ILE B O   1 
ATOM   4977  C CB  . ILE B 1 285 ? 96.349  112.383 111.992 1.00 49.72  ? 285 ILE B CB  1 
ATOM   4978  C CG1 . ILE B 1 285 ? 96.038  111.027 112.622 1.00 49.72  ? 285 ILE B CG1 1 
ATOM   4979  C CG2 . ILE B 1 285 ? 95.425  112.640 110.814 1.00 49.72  ? 285 ILE B CG2 1 
ATOM   4980  C CD1 . ILE B 1 285 ? 96.265  109.859 111.691 1.00 49.72  ? 285 ILE B CD1 1 
ATOM   4981  N N   . TRP B 1 286 ? 98.009  114.673 110.596 1.00 59.70  ? 286 TRP B N   1 
ATOM   4982  C CA  . TRP B 1 286 ? 98.159  115.633 109.508 1.00 59.70  ? 286 TRP B CA  1 
ATOM   4983  C C   . TRP B 1 286 ? 99.498  115.465 108.802 1.00 59.70  ? 286 TRP B C   1 
ATOM   4984  O O   . TRP B 1 286 ? 99.567  115.429 107.566 1.00 59.70  ? 286 TRP B O   1 
ATOM   4985  C CB  . TRP B 1 286 ? 98.009  117.049 110.058 1.00 59.70  ? 286 TRP B CB  1 
ATOM   4986  C CG  . TRP B 1 286 ? 97.539  118.032 109.058 1.00 59.70  ? 286 TRP B CG  1 
ATOM   4987  C CD1 . TRP B 1 286 ? 96.257  118.241 108.650 1.00 59.70  ? 286 TRP B CD1 1 
ATOM   4988  C CD2 . TRP B 1 286 ? 98.349  118.957 108.332 1.00 59.70  ? 286 TRP B CD2 1 
ATOM   4989  N NE1 . TRP B 1 286 ? 96.217  119.241 107.710 1.00 59.70  ? 286 TRP B NE1 1 
ATOM   4990  C CE2 . TRP B 1 286 ? 97.491  119.697 107.497 1.00 59.70  ? 286 TRP B CE2 1 
ATOM   4991  C CE3 . TRP B 1 286 ? 99.717  119.230 108.306 1.00 59.70  ? 286 TRP B CE3 1 
ATOM   4992  C CZ2 . TRP B 1 286 ? 97.957  120.691 106.648 1.00 59.70  ? 286 TRP B CZ2 1 
ATOM   4993  C CZ3 . TRP B 1 286 ? 100.175 120.212 107.466 1.00 59.70  ? 286 TRP B CZ3 1 
ATOM   4994  C CH2 . TRP B 1 286 ? 99.300  120.933 106.646 1.00 59.70  ? 286 TRP B CH2 1 
ATOM   4995  N N   . MET B 1 287 ? 100.577 115.337 109.570 1.00 54.11  ? 287 MET B N   1 
ATOM   4996  C CA  . MET B 1 287 ? 101.891 115.236 108.954 1.00 54.11  ? 287 MET B CA  1 
ATOM   4997  C C   . MET B 1 287 ? 102.094 113.881 108.287 1.00 54.11  ? 287 MET B C   1 
ATOM   4998  O O   . MET B 1 287 ? 102.784 113.795 107.264 1.00 54.11  ? 287 MET B O   1 
ATOM   4999  C CB  . MET B 1 287 ? 102.968 115.511 110.000 1.00 54.11  ? 287 MET B CB  1 
ATOM   5000  C CG  . MET B 1 287 ? 104.377 115.441 109.473 1.00 54.11  ? 287 MET B CG  1 
ATOM   5001  S SD  . MET B 1 287 ? 105.421 116.656 110.291 1.00 54.11  ? 287 MET B SD  1 
ATOM   5002  C CE  . MET B 1 287 ? 104.444 118.140 110.062 1.00 54.11  ? 287 MET B CE  1 
ATOM   5003  N N   . ALA B 1 288 ? 101.479 112.823 108.821 1.00 57.66  ? 288 ALA B N   1 
ATOM   5004  C CA  . ALA B 1 288 ? 101.518 111.531 108.148 1.00 57.66  ? 288 ALA B CA  1 
ATOM   5005  C C   . ALA B 1 288 ? 100.788 111.588 106.815 1.00 57.66  ? 288 ALA B C   1 
ATOM   5006  O O   . ALA B 1 288 ? 101.240 110.996 105.829 1.00 57.66  ? 288 ALA B O   1 
ATOM   5007  C CB  . ALA B 1 288 ? 100.917 110.451 109.045 1.00 57.66  ? 288 ALA B CB  1 
ATOM   5008  N N   . VAL B 1 289 ? 99.658  112.295 106.758 1.00 60.32  ? 289 VAL B N   1 
ATOM   5009  C CA  . VAL B 1 289 ? 98.957  112.436 105.485 1.00 60.32  ? 289 VAL B CA  1 
ATOM   5010  C C   . VAL B 1 289 ? 99.784  113.263 104.507 1.00 60.32  ? 289 VAL B C   1 
ATOM   5011  O O   . VAL B 1 289 ? 99.791  112.994 103.300 1.00 60.32  ? 289 VAL B O   1 
ATOM   5012  C CB  . VAL B 1 289 ? 97.556  113.036 105.695 1.00 60.32  ? 289 VAL B CB  1 
ATOM   5013  C CG1 . VAL B 1 289 ? 96.896  113.307 104.356 1.00 60.32  ? 289 VAL B CG1 1 
ATOM   5014  C CG2 . VAL B 1 289 ? 96.700  112.088 106.510 1.00 60.32  ? 289 VAL B CG2 1 
ATOM   5015  N N   . CYS B 1 290 ? 100.491 114.281 105.002 1.00 57.45  ? 290 CYS B N   1 
ATOM   5016  C CA  . CYS B 1 290 ? 101.375 115.044 104.121 1.00 57.45  ? 290 CYS B CA  1 
ATOM   5017  C C   . CYS B 1 290 ? 102.483 114.162 103.552 1.00 57.45  ? 290 CYS B C   1 
ATOM   5018  O O   . CYS B 1 290 ? 102.793 114.224 102.352 1.00 57.45  ? 290 CYS B O   1 
ATOM   5019  C CB  . CYS B 1 290 ? 101.970 116.232 104.875 1.00 57.45  ? 290 CYS B CB  1 
ATOM   5020  S SG  . CYS B 1 290 ? 101.021 117.760 104.716 1.00 57.45  ? 290 CYS B SG  1 
ATOM   5021  N N   . LEU B 1 291 ? 103.084 113.326 104.399 1.00 61.28  ? 291 LEU B N   1 
ATOM   5022  C CA  . LEU B 1 291 ? 104.096 112.390 103.924 1.00 61.28  ? 291 LEU B CA  1 
ATOM   5023  C C   . LEU B 1 291 ? 103.507 111.415 102.913 1.00 61.28  ? 291 LEU B C   1 
ATOM   5024  O O   . LEU B 1 291 ? 104.160 111.061 101.925 1.00 61.28  ? 291 LEU B O   1 
ATOM   5025  C CB  . LEU B 1 291 ? 104.704 111.635 105.103 1.00 61.28  ? 291 LEU B CB  1 
ATOM   5026  C CG  . LEU B 1 291 ? 105.992 110.863 104.822 1.00 61.28  ? 291 LEU B CG  1 
ATOM   5027  C CD1 . LEU B 1 291 ? 107.205 111.748 105.046 1.00 61.28  ? 291 LEU B CD1 1 
ATOM   5028  C CD2 . LEU B 1 291 ? 106.067 109.614 105.688 1.00 61.28  ? 291 LEU B CD2 1 
ATOM   5029  N N   . LEU B 1 292 ? 102.274 110.963 103.150 1.00 63.35  ? 292 LEU B N   1 
ATOM   5030  C CA  . LEU B 1 292 ? 101.617 110.060 102.212 1.00 63.35  ? 292 LEU B CA  1 
ATOM   5031  C C   . LEU B 1 292 ? 101.382 110.740 100.870 1.00 63.35  ? 292 LEU B C   1 
ATOM   5032  O O   . LEU B 1 292 ? 101.515 110.110 99.819  1.00 63.35  ? 292 LEU B O   1 
ATOM   5033  C CB  . LEU B 1 292 ? 100.306 109.546 102.815 1.00 63.35  ? 292 LEU B CB  1 
ATOM   5034  C CG  . LEU B 1 292 ? 99.216  108.891 101.959 1.00 63.35  ? 292 LEU B CG  1 
ATOM   5035  C CD1 . LEU B 1 292 ? 98.404  107.948 102.825 1.00 63.35  ? 292 LEU B CD1 1 
ATOM   5036  C CD2 . LEU B 1 292 ? 98.283  109.915 101.327 1.00 63.35  ? 292 LEU B CD2 1 
ATOM   5037  N N   . PHE B 1 293 ? 101.014 112.021 100.884 1.00 62.11  ? 293 PHE B N   1 
ATOM   5038  C CA  . PHE B 1 293 ? 100.832 112.746 99.630  1.00 62.11  ? 293 PHE B CA  1 
ATOM   5039  C C   . PHE B 1 293 ? 102.148 112.880 98.875  1.00 62.11  ? 293 PHE B C   1 
ATOM   5040  O O   . PHE B 1 293 ? 102.188 112.737 97.645  1.00 62.11  ? 293 PHE B O   1 
ATOM   5041  C CB  . PHE B 1 293 ? 100.226 114.121 99.898  1.00 62.11  ? 293 PHE B CB  1 
ATOM   5042  C CG  . PHE B 1 293 ? 98.757  114.190 99.627  1.00 62.11  ? 293 PHE B CG  1 
ATOM   5043  C CD1 . PHE B 1 293 ? 97.885  113.321 100.257 1.00 62.11  ? 293 PHE B CD1 1 
ATOM   5044  C CD2 . PHE B 1 293 ? 98.248  115.112 98.733  1.00 62.11  ? 293 PHE B CD2 1 
ATOM   5045  C CE1 . PHE B 1 293 ? 96.529  113.377 100.008 1.00 62.11  ? 293 PHE B CE1 1 
ATOM   5046  C CE2 . PHE B 1 293 ? 96.893  115.173 98.479  1.00 62.11  ? 293 PHE B CE2 1 
ATOM   5047  C CZ  . PHE B 1 293 ? 96.032  114.305 99.117  1.00 62.11  ? 293 PHE B CZ  1 
ATOM   5048  N N   . VAL B 1 294 ? 103.237 113.157 99.592  1.00 66.13  ? 294 VAL B N   1 
ATOM   5049  C CA  . VAL B 1 294 ? 104.541 113.234 98.937  1.00 66.13  ? 294 VAL B CA  1 
ATOM   5050  C C   . VAL B 1 294 ? 104.920 111.880 98.339  1.00 66.13  ? 294 VAL B C   1 
ATOM   5051  O O   . VAL B 1 294 ? 105.419 111.794 97.206  1.00 66.13  ? 294 VAL B O   1 
ATOM   5052  C CB  . VAL B 1 294 ? 105.603 113.741 99.929  1.00 66.13  ? 294 VAL B CB  1 
ATOM   5053  C CG1 . VAL B 1 294 ? 106.980 113.660 99.314  1.00 66.13  ? 294 VAL B CG1 1 
ATOM   5054  C CG2 . VAL B 1 294 ? 105.289 115.167 100.345 1.00 66.13  ? 294 VAL B CG2 1 
ATOM   5055  N N   . PHE B 1 295 ? 104.680 110.801 99.088  1.00 74.84  ? 295 PHE B N   1 
ATOM   5056  C CA  . PHE B 1 295 ? 104.945 109.463 98.571  1.00 74.84  ? 295 PHE B CA  1 
ATOM   5057  C C   . PHE B 1 295 ? 104.082 109.164 97.352  1.00 74.84  ? 295 PHE B C   1 
ATOM   5058  O O   . PHE B 1 295 ? 104.531 108.497 96.416  1.00 74.84  ? 295 PHE B O   1 
ATOM   5059  C CB  . PHE B 1 295 ? 104.716 108.421 99.668  1.00 74.84  ? 295 PHE B CB  1 
ATOM   5060  C CG  . PHE B 1 295 ? 103.849 107.263 99.244  1.00 74.84  ? 295 PHE B CG  1 
ATOM   5061  C CD1 . PHE B 1 295 ? 104.381 106.201 98.532  1.00 74.84  ? 295 PHE B CD1 1 
ATOM   5062  C CD2 . PHE B 1 295 ? 102.504 107.230 99.575  1.00 74.84  ? 295 PHE B CD2 1 
ATOM   5063  C CE1 . PHE B 1 295 ? 103.584 105.138 98.144  1.00 74.84  ? 295 PHE B CE1 1 
ATOM   5064  C CE2 . PHE B 1 295 ? 101.703 106.168 99.191  1.00 74.84  ? 295 PHE B CE2 1 
ATOM   5065  C CZ  . PHE B 1 295 ? 102.245 105.121 98.476  1.00 74.84  ? 295 PHE B CZ  1 
ATOM   5066  N N   . SER B 1 296 ? 102.834 109.633 97.354  1.00 74.38  ? 296 SER B N   1 
ATOM   5067  C CA  . SER B 1 296 ? 101.962 109.430 96.203  1.00 74.38  ? 296 SER B CA  1 
ATOM   5068  C C   . SER B 1 296 ? 102.483 110.174 94.982  1.00 74.38  ? 296 SER B C   1 
ATOM   5069  O O   . SER B 1 296 ? 102.393 109.671 93.857  1.00 74.38  ? 296 SER B O   1 
ATOM   5070  C CB  . SER B 1 296 ? 100.539 109.874 96.539  1.00 74.38  ? 296 SER B CB  1 
ATOM   5071  O OG  . SER B 1 296 ? 99.645  109.558 95.486  1.00 74.38  ? 296 SER B OG  1 
ATOM   5072  N N   . ALA B 1 297 ? 103.019 111.380 95.182  1.00 74.51  ? 297 ALA B N   1 
ATOM   5073  C CA  . ALA B 1 297 ? 103.638 112.097 94.070  1.00 74.51  ? 297 ALA B CA  1 
ATOM   5074  C C   . ALA B 1 297 ? 104.831 111.325 93.518  1.00 74.51  ? 297 ALA B C   1 
ATOM   5075  O O   . ALA B 1 297 ? 104.993 111.196 92.296  1.00 74.51  ? 297 ALA B O   1 
ATOM   5076  C CB  . ALA B 1 297 ? 104.061 113.495 94.515  1.00 74.51  ? 297 ALA B CB  1 
ATOM   5077  N N   . LEU B 1 298 ? 105.672 110.789 94.405  1.00 77.08  ? 298 LEU B N   1 
ATOM   5078  C CA  . LEU B 1 298 ? 106.795 109.977 93.942  1.00 77.08  ? 298 LEU B CA  1 
ATOM   5079  C C   . LEU B 1 298 ? 106.308 108.748 93.180  1.00 77.08  ? 298 LEU B C   1 
ATOM   5080  O O   . LEU B 1 298 ? 106.867 108.388 92.136  1.00 77.08  ? 298 LEU B O   1 
ATOM   5081  C CB  . LEU B 1 298 ? 107.675 109.566 95.122  1.00 77.08  ? 298 LEU B CB  1 
ATOM   5082  C CG  . LEU B 1 298 ? 109.034 108.943 94.788  1.00 77.08  ? 298 LEU B CG  1 
ATOM   5083  C CD1 . LEU B 1 298 ? 110.084 109.398 95.786  1.00 77.08  ? 298 LEU B CD1 1 
ATOM   5084  C CD2 . LEU B 1 298 ? 108.954 107.422 94.761  1.00 77.08  ? 298 LEU B CD2 1 
ATOM   5085  N N   . LEU B 1 299 ? 105.266 108.091 93.693  1.00 77.02  ? 299 LEU B N   1 
ATOM   5086  C CA  . LEU B 1 299 ? 104.736 106.893 93.051  1.00 77.02  ? 299 LEU B CA  1 
ATOM   5087  C C   . LEU B 1 299 ? 104.168 107.203 91.674  1.00 77.02  ? 299 LEU B C   1 
ATOM   5088  O O   . LEU B 1 299 ? 104.382 106.441 90.725  1.00 77.02  ? 299 LEU B O   1 
ATOM   5089  C CB  . LEU B 1 299 ? 103.668 106.257 93.942  1.00 77.02  ? 299 LEU B CB  1 
ATOM   5090  C CG  . LEU B 1 299 ? 103.014 104.965 93.451  1.00 77.02  ? 299 LEU B CG  1 
ATOM   5091  C CD1 . LEU B 1 299 ? 102.981 103.933 94.565  1.00 77.02  ? 299 LEU B CD1 1 
ATOM   5092  C CD2 . LEU B 1 299 ? 101.609 105.234 92.927  1.00 77.02  ? 299 LEU B CD2 1 
ATOM   5093  N N   . GLU B 1 300 ? 103.434 108.311 91.543  1.00 80.58  ? 300 GLU B N   1 
ATOM   5094  C CA  . GLU B 1 300 ? 102.878 108.660 90.241  1.00 80.58  ? 300 GLU B CA  1 
ATOM   5095  C C   . GLU B 1 300 ? 103.981 109.015 89.253  1.00 80.58  ? 300 GLU B C   1 
ATOM   5096  O O   . GLU B 1 300 ? 103.895 108.659 88.072  1.00 80.58  ? 300 GLU B O   1 
ATOM   5097  C CB  . GLU B 1 300 ? 101.851 109.792 90.378  1.00 80.58  ? 300 GLU B CB  1 
ATOM   5098  C CG  . GLU B 1 300 ? 102.394 111.179 90.709  1.00 80.58  ? 300 GLU B CG  1 
ATOM   5099  C CD  . GLU B 1 300 ? 102.966 111.908 89.506  1.00 80.58  ? 300 GLU B CD  1 
ATOM   5100  O OE1 . GLU B 1 300 ? 102.616 111.538 88.366  1.00 80.58  ? 300 GLU B OE1 1 
ATOM   5101  O OE2 . GLU B 1 300 ? 103.771 112.843 89.701  1.00 80.58  ? 300 GLU B OE2 1 
ATOM   5102  N N   . TYR B 1 301 ? 105.032 109.704 89.712  1.00 85.93  ? 301 TYR B N   1 
ATOM   5103  C CA  . TYR B 1 301 ? 106.148 109.981 88.813  1.00 85.93  ? 301 TYR B CA  1 
ATOM   5104  C C   . TYR B 1 301 ? 106.819 108.691 88.358  1.00 85.93  ? 301 TYR B C   1 
ATOM   5105  O O   . TYR B 1 301 ? 107.160 108.541 87.177  1.00 85.93  ? 301 TYR B O   1 
ATOM   5106  C CB  . TYR B 1 301 ? 107.171 110.894 89.483  1.00 85.93  ? 301 TYR B CB  1 
ATOM   5107  C CG  . TYR B 1 301 ? 108.506 110.891 88.771  1.00 85.93  ? 301 TYR B CG  1 
ATOM   5108  C CD1 . TYR B 1 301 ? 108.700 111.642 87.620  1.00 85.93  ? 301 TYR B CD1 1 
ATOM   5109  C CD2 . TYR B 1 301 ? 109.565 110.124 89.239  1.00 85.93  ? 301 TYR B CD2 1 
ATOM   5110  C CE1 . TYR B 1 301 ? 109.913 111.638 86.961  1.00 85.93  ? 301 TYR B CE1 1 
ATOM   5111  C CE2 . TYR B 1 301 ? 110.778 110.110 88.584  1.00 85.93  ? 301 TYR B CE2 1 
ATOM   5112  C CZ  . TYR B 1 301 ? 110.949 110.871 87.448  1.00 85.93  ? 301 TYR B CZ  1 
ATOM   5113  O OH  . TYR B 1 301 ? 112.158 110.864 86.794  1.00 85.93  ? 301 TYR B OH  1 
ATOM   5114  N N   . ALA B 1 302 ? 107.027 107.753 89.284  1.00 81.27  ? 302 ALA B N   1 
ATOM   5115  C CA  . ALA B 1 302 ? 107.647 106.484 88.919  1.00 81.27  ? 302 ALA B CA  1 
ATOM   5116  C C   . ALA B 1 302 ? 106.780 105.712 87.934  1.00 81.27  ? 302 ALA B C   1 
ATOM   5117  O O   . ALA B 1 302 ? 107.291 105.117 86.979  1.00 81.27  ? 302 ALA B O   1 
ATOM   5118  C CB  . ALA B 1 302 ? 107.915 105.649 90.170  1.00 81.27  ? 302 ALA B CB  1 
ATOM   5119  N N   . ALA B 1 303 ? 105.463 105.712 88.150  1.00 79.40  ? 303 ALA B N   1 
ATOM   5120  C CA  . ALA B 1 303 ? 104.562 105.025 87.230  1.00 79.40  ? 303 ALA B CA  1 
ATOM   5121  C C   . ALA B 1 303 ? 104.589 105.664 85.849  1.00 79.40  ? 303 ALA B C   1 
ATOM   5122  O O   . ALA B 1 303 ? 104.584 104.961 84.832  1.00 79.40  ? 303 ALA B O   1 
ATOM   5123  C CB  . ALA B 1 303 ? 103.141 105.020 87.793  1.00 79.40  ? 303 ALA B CB  1 
ATOM   5124  N N   . VAL B 1 304 ? 104.615 106.998 85.790  1.00 80.11  ? 304 VAL B N   1 
ATOM   5125  C CA  . VAL B 1 304 ? 104.673 107.684 84.502  1.00 80.11  ? 304 VAL B CA  1 
ATOM   5126  C C   . VAL B 1 304 ? 105.972 107.353 83.779  1.00 80.11  ? 304 VAL B C   1 
ATOM   5127  O O   . VAL B 1 304 ? 105.977 107.088 82.569  1.00 80.11  ? 304 VAL B O   1 
ATOM   5128  C CB  . VAL B 1 304 ? 104.499 109.202 84.696  1.00 80.11  ? 304 VAL B CB  1 
ATOM   5129  C CG1 . VAL B 1 304 ? 104.939 109.954 83.454  1.00 80.11  ? 304 VAL B CG1 1 
ATOM   5130  C CG2 . VAL B 1 304 ? 103.053 109.526 85.027  1.00 80.11  ? 304 VAL B CG2 1 
ATOM   5131  N N   . ASN B 1 305 ? 107.092 107.356 84.505  1.00 84.51  ? 305 ASN B N   1 
ATOM   5132  C CA  . ASN B 1 305 ? 108.370 107.014 83.886  1.00 84.51  ? 305 ASN B CA  1 
ATOM   5133  C C   . ASN B 1 305 ? 108.378 105.572 83.393  1.00 84.51  ? 305 ASN B C   1 
ATOM   5134  O O   . ASN B 1 305 ? 108.918 105.277 82.321  1.00 84.51  ? 305 ASN B O   1 
ATOM   5135  C CB  . ASN B 1 305 ? 109.513 107.252 84.871  1.00 84.51  ? 305 ASN B CB  1 
ATOM   5136  C CG  . ASN B 1 305 ? 110.844 107.471 84.176  1.00 84.51  ? 305 ASN B CG  1 
ATOM   5137  O OD1 . ASN B 1 305 ? 111.224 106.713 83.285  1.00 84.51  ? 305 ASN B OD1 1 
ATOM   5138  N ND2 . ASN B 1 305 ? 111.559 108.514 84.582  1.00 84.51  ? 305 ASN B ND2 1 
ATOM   5139  N N   . PHE B 1 306 ? 107.791 104.656 84.168  1.00 82.69  ? 306 PHE B N   1 
ATOM   5140  C CA  . PHE B 1 306 ? 107.708 103.262 83.742  1.00 82.69  ? 306 PHE B CA  1 
ATOM   5141  C C   . PHE B 1 306 ? 106.860 103.117 82.484  1.00 82.69  ? 306 PHE B C   1 
ATOM   5142  O O   . PHE B 1 306 ? 107.216 102.362 81.571  1.00 82.69  ? 306 PHE B O   1 
ATOM   5143  C CB  . PHE B 1 306 ? 107.145 102.406 84.879  1.00 82.69  ? 306 PHE B CB  1 
ATOM   5144  C CG  . PHE B 1 306 ? 106.229 101.307 84.420  1.00 82.69  ? 306 PHE B CG  1 
ATOM   5145  C CD1 . PHE B 1 306 ? 106.740 100.123 83.917  1.00 82.69  ? 306 PHE B CD1 1 
ATOM   5146  C CD2 . PHE B 1 306 ? 104.854 101.456 84.503  1.00 82.69  ? 306 PHE B CD2 1 
ATOM   5147  C CE1 . PHE B 1 306 ? 105.898 99.112  83.498  1.00 82.69  ? 306 PHE B CE1 1 
ATOM   5148  C CE2 . PHE B 1 306 ? 104.007 100.449 84.086  1.00 82.69  ? 306 PHE B CE2 1 
ATOM   5149  C CZ  . PHE B 1 306 ? 104.529 99.275  83.583  1.00 82.69  ? 306 PHE B CZ  1 
ATOM   5150  N N   . VAL B 1 307 ? 105.731 103.827 82.421  1.00 79.83  ? 307 VAL B N   1 
ATOM   5151  C CA  . VAL B 1 307 ? 104.883 103.775 81.233  1.00 79.83  ? 307 VAL B CA  1 
ATOM   5152  C C   . VAL B 1 307 ? 105.629 104.321 80.023  1.00 79.83  ? 307 VAL B C   1 
ATOM   5153  O O   . VAL B 1 307 ? 105.577 103.745 78.930  1.00 79.83  ? 307 VAL B O   1 
ATOM   5154  C CB  . VAL B 1 307 ? 103.567 104.534 81.480  1.00 79.83  ? 307 VAL B CB  1 
ATOM   5155  C CG1 . VAL B 1 307 ? 102.789 104.690 80.184  1.00 79.83  ? 307 VAL B CG1 1 
ATOM   5156  C CG2 . VAL B 1 307 ? 102.728 103.807 82.515  1.00 79.83  ? 307 VAL B CG2 1 
ATOM   5157  N N   . SER B 1 308 ? 106.344 105.435 80.201  1.00 83.62  ? 308 SER B N   1 
ATOM   5158  C CA  . SER B 1 308 ? 107.095 106.024 79.098  1.00 83.62  ? 308 SER B CA  1 
ATOM   5159  C C   . SER B 1 308 ? 108.254 105.145 78.644  1.00 83.62  ? 308 SER B C   1 
ATOM   5160  O O   . SER B 1 308 ? 108.791 105.367 77.554  1.00 83.62  ? 308 SER B O   1 
ATOM   5161  C CB  . SER B 1 308 ? 107.619 107.405 79.494  1.00 83.62  ? 308 SER B CB  1 
ATOM   5162  O OG  . SER B 1 308 ? 108.400 107.967 78.455  1.00 83.62  ? 308 SER B OG  1 
ATOM   5163  N N   . ARG B 1 309 ? 108.652 104.162 79.448  1.00 86.40  ? 309 ARG B N   1 
ATOM   5164  C CA  . ARG B 1 309 ? 109.727 103.245 79.087  1.00 86.40  ? 309 ARG B CA  1 
ATOM   5165  C C   . ARG B 1 309 ? 109.120 102.031 78.392  1.00 86.40  ? 309 ARG B C   1 
ATOM   5166  O O   . ARG B 1 309 ? 108.378 101.261 79.010  1.00 86.40  ? 309 ARG B O   1 
ATOM   5167  C CB  . ARG B 1 309 ? 110.523 102.832 80.322  1.00 86.40  ? 309 ARG B CB  1 
ATOM   5168  N N   . GLN B 1 310 ? 109.437 101.867 77.109  1.00 101.97 ? 310 GLN B N   1 
ATOM   5169  C CA  . GLN B 1 310 ? 108.943 100.755 76.297  1.00 101.97 ? 310 GLN B CA  1 
ATOM   5170  C C   . GLN B 1 310 ? 107.418 100.681 76.304  1.00 101.97 ? 310 GLN B C   1 
ATOM   5171  O O   . GLN B 1 310 ? 106.833 99.767  76.884  1.00 101.97 ? 310 GLN B O   1 
ATOM   5172  C CB  . GLN B 1 310 ? 109.536 99.428  76.781  1.00 101.97 ? 310 GLN B CB  1 
ATOM   5173  C CG  . GLN B 1 310 ? 110.089 98.549  75.669  1.00 101.97 ? 310 GLN B CG  1 
ATOM   5174  C CD  . GLN B 1 310 ? 109.017 97.721  74.990  1.00 101.97 ? 310 GLN B CD  1 
ATOM   5175  O OE1 . GLN B 1 310 ? 107.963 97.456  75.568  1.00 101.97 ? 310 GLN B OE1 1 
ATOM   5176  N NE2 . GLN B 1 310 ? 109.281 97.306  73.757  1.00 101.97 ? 310 GLN B NE2 1 
ATOM   5177  N N   . ARG B 1 376 ? 105.384 107.650 70.186  1.00 98.62  ? 385 ARG B N   1 
ATOM   5178  C CA  . ARG B 1 376 ? 106.013 106.335 70.186  1.00 98.62  ? 385 ARG B CA  1 
ATOM   5179  C C   . ARG B 1 376 ? 105.043 105.265 70.671  1.00 98.62  ? 385 ARG B C   1 
ATOM   5180  O O   . ARG B 1 376 ? 104.793 105.144 71.871  1.00 98.62  ? 385 ARG B O   1 
ATOM   5181  C CB  . ARG B 1 376 ? 107.269 106.341 71.059  1.00 98.62  ? 385 ARG B CB  1 
ATOM   5182  C CG  . ARG B 1 376 ? 107.961 104.993 71.158  1.00 98.62  ? 385 ARG B CG  1 
ATOM   5183  C CD  . ARG B 1 376 ? 109.222 105.081 72.000  1.00 98.62  ? 385 ARG B CD  1 
ATOM   5184  N NE  . ARG B 1 376 ? 109.825 103.772 72.216  1.00 98.62  ? 385 ARG B NE  1 
ATOM   5185  C CZ  . ARG B 1 376 ? 109.535 102.973 73.234  1.00 98.62  ? 385 ARG B CZ  1 
ATOM   5186  N NH1 . ARG B 1 376 ? 108.645 103.316 74.150  1.00 98.62  ? 385 ARG B NH1 1 
ATOM   5187  N NH2 . ARG B 1 376 ? 110.153 101.799 73.334  1.00 98.62  ? 385 ARG B NH2 1 
ATOM   5188  N N   . LYS B 1 377 ? 104.504 104.494 69.725  1.00 103.96 ? 386 LYS B N   1 
ATOM   5189  C CA  . LYS B 1 377 ? 103.548 103.426 70.020  1.00 103.96 ? 386 LYS B CA  1 
ATOM   5190  C C   . LYS B 1 377 ? 102.359 103.956 70.817  1.00 103.96 ? 386 LYS B C   1 
ATOM   5191  O O   . LYS B 1 377 ? 101.872 103.310 71.747  1.00 103.96 ? 386 LYS B O   1 
ATOM   5192  C CB  . LYS B 1 377 ? 104.227 102.268 70.755  1.00 103.96 ? 386 LYS B CB  1 
ATOM   5193  C CG  . LYS B 1 377 ? 105.505 101.776 70.092  1.00 103.96 ? 386 LYS B CG  1 
ATOM   5194  C CD  . LYS B 1 377 ? 106.178 100.692 70.920  1.00 103.96 ? 386 LYS B CD  1 
ATOM   5195  C CE  . LYS B 1 377 ? 106.308 101.107 72.378  1.00 103.96 ? 386 LYS B CE  1 
ATOM   5196  N NZ  . LYS B 1 377 ? 107.388 100.358 73.077  1.00 103.96 ? 386 LYS B NZ  1 
ATOM   5197  N N   . VAL B 1 378 ? 101.894 105.152 70.436  1.00 104.00 ? 387 VAL B N   1 
ATOM   5198  C CA  . VAL B 1 378 ? 100.808 105.906 71.068  1.00 104.00 ? 387 VAL B CA  1 
ATOM   5199  C C   . VAL B 1 378 ? 100.791 105.744 72.586  1.00 104.00 ? 387 VAL B C   1 
ATOM   5200  O O   . VAL B 1 378 ? 99.726  105.760 73.213  1.00 104.00 ? 387 VAL B O   1 
ATOM   5201  C CB  . VAL B 1 378 ? 99.437  105.540 70.456  1.00 104.00 ? 387 VAL B CB  1 
ATOM   5202  C CG1 . VAL B 1 378 ? 99.420  105.865 68.969  1.00 104.00 ? 387 VAL B CG1 1 
ATOM   5203  C CG2 . VAL B 1 378 ? 99.067  104.076 70.696  1.00 104.00 ? 387 VAL B CG2 1 
ATOM   5204  N N   . PHE B 1 379 ? 101.973 105.610 73.188  1.00 104.66 ? 388 PHE B N   1 
ATOM   5205  C CA  . PHE B 1 379 ? 102.089 105.558 74.639  1.00 104.66 ? 388 PHE B CA  1 
ATOM   5206  C C   . PHE B 1 379 ? 102.310 106.933 75.249  1.00 104.66 ? 388 PHE B C   1 
ATOM   5207  O O   . PHE B 1 379 ? 101.922 107.164 76.401  1.00 104.66 ? 388 PHE B O   1 
ATOM   5208  C CB  . PHE B 1 379 ? 103.236 104.629 75.047  1.00 104.66 ? 388 PHE B CB  1 
ATOM   5209  C CG  . PHE B 1 379 ? 102.831 103.190 75.184  1.00 104.66 ? 388 PHE B CG  1 
ATOM   5210  C CD1 . PHE B 1 379 ? 101.557 102.777 74.832  1.00 104.66 ? 388 PHE B CD1 1 
ATOM   5211  C CD2 . PHE B 1 379 ? 103.726 102.249 75.666  1.00 104.66 ? 388 PHE B CD2 1 
ATOM   5212  C CE1 . PHE B 1 379 ? 101.182 101.451 74.956  1.00 104.66 ? 388 PHE B CE1 1 
ATOM   5213  C CE2 . PHE B 1 379 ? 103.358 100.922 75.793  1.00 104.66 ? 388 PHE B CE2 1 
ATOM   5214  C CZ  . PHE B 1 379 ? 102.084 100.523 75.438  1.00 104.66 ? 388 PHE B CZ  1 
ATOM   5215  N N   . ILE B 1 380 ? 102.923 107.849 74.497  1.00 95.92  ? 389 ILE B N   1 
ATOM   5216  C CA  . ILE B 1 380 ? 103.138 109.204 74.994  1.00 95.92  ? 389 ILE B CA  1 
ATOM   5217  C C   . ILE B 1 380 ? 101.804 109.894 75.243  1.00 95.92  ? 389 ILE B C   1 
ATOM   5218  O O   . ILE B 1 380 ? 101.636 110.611 76.235  1.00 95.92  ? 389 ILE B O   1 
ATOM   5219  C CB  . ILE B 1 380 ? 104.022 109.997 74.013  1.00 95.92  ? 389 ILE B CB  1 
ATOM   5220  C CG1 . ILE B 1 380 ? 105.499 109.830 74.374  1.00 95.92  ? 389 ILE B CG1 1 
ATOM   5221  C CG2 . ILE B 1 380 ? 103.642 111.472 73.999  1.00 95.92  ? 389 ILE B CG2 1 
ATOM   5222  C CD1 . ILE B 1 380 ? 106.449 110.294 73.293  1.00 95.92  ? 389 ILE B CD1 1 
ATOM   5223  N N   . ASP B 1 381 ? 100.833 109.681 74.352  1.00 98.42  ? 390 ASP B N   1 
ATOM   5224  C CA  . ASP B 1 381 ? 99.522  110.302 74.518  1.00 98.42  ? 390 ASP B CA  1 
ATOM   5225  C C   . ASP B 1 381 ? 98.840  109.819 75.792  1.00 98.42  ? 390 ASP B C   1 
ATOM   5226  O O   . ASP B 1 381 ? 98.305  110.621 76.568  1.00 98.42  ? 390 ASP B O   1 
ATOM   5227  C CB  . ASP B 1 381 ? 98.651  110.011 73.295  1.00 98.42  ? 390 ASP B CB  1 
ATOM   5228  C CG  . ASP B 1 381 ? 97.393  110.855 73.261  1.00 98.42  ? 390 ASP B CG  1 
ATOM   5229  O OD1 . ASP B 1 381 ? 97.343  111.879 73.974  1.00 98.42  ? 390 ASP B OD1 1 
ATOM   5230  O OD2 . ASP B 1 381 ? 96.454  110.492 72.522  1.00 98.42  ? 390 ASP B OD2 1 
ATOM   5231  N N   . ARG B 1 382 ? 98.856  108.506 76.030  1.00 94.10  ? 391 ARG B N   1 
ATOM   5232  C CA  . ARG B 1 382 ? 98.223  107.965 77.230  1.00 94.10  ? 391 ARG B CA  1 
ATOM   5233  C C   . ARG B 1 382 ? 98.955  108.407 78.490  1.00 94.10  ? 391 ARG B C   1 
ATOM   5234  O O   . ARG B 1 382 ? 98.322  108.707 79.510  1.00 94.10  ? 391 ARG B O   1 
ATOM   5235  C CB  . ARG B 1 382 ? 98.162  106.440 77.147  1.00 94.10  ? 391 ARG B CB  1 
ATOM   5236  C CG  . ARG B 1 382 ? 97.751  105.908 75.782  1.00 94.10  ? 391 ARG B CG  1 
ATOM   5237  C CD  . ARG B 1 382 ? 96.236  105.849 75.625  1.00 94.10  ? 391 ARG B CD  1 
ATOM   5238  N NE  . ARG B 1 382 ? 95.628  107.172 75.533  1.00 94.10  ? 391 ARG B NE  1 
ATOM   5239  C CZ  . ARG B 1 382 ? 95.637  107.929 74.444  1.00 94.10  ? 391 ARG B CZ  1 
ATOM   5240  N NH1 . ARG B 1 382 ? 96.216  107.526 73.325  1.00 94.10  ? 391 ARG B NH1 1 
ATOM   5241  N NH2 . ARG B 1 382 ? 95.049  109.122 74.479  1.00 94.10  ? 391 ARG B NH2 1 
ATOM   5242  N N   . ALA B 1 383 ? 100.289 108.447 78.442  1.00 86.22  ? 392 ALA B N   1 
ATOM   5243  C CA  . ALA B 1 383 ? 101.052 108.913 79.594  1.00 86.22  ? 392 ALA B CA  1 
ATOM   5244  C C   . ALA B 1 383 ? 100.744 110.373 79.904  1.00 86.22  ? 392 ALA B C   1 
ATOM   5245  O O   . ALA B 1 383 ? 100.568 110.743 81.069  1.00 86.22  ? 392 ALA B O   1 
ATOM   5246  C CB  . ALA B 1 383 ? 102.546 108.712 79.345  1.00 86.22  ? 392 ALA B CB  1 
ATOM   5247  N N   . LYS B 1 384 ? 100.661 111.216 78.871  1.00 87.54  ? 393 LYS B N   1 
ATOM   5248  C CA  . LYS B 1 384 ? 100.300 112.614 79.080  1.00 87.54  ? 393 LYS B CA  1 
ATOM   5249  C C   . LYS B 1 384 ? 98.893  112.740 79.645  1.00 87.54  ? 393 LYS B C   1 
ATOM   5250  O O   . LYS B 1 384 ? 98.644  113.560 80.537  1.00 87.54  ? 393 LYS B O   1 
ATOM   5251  C CB  . LYS B 1 384 ? 100.413 113.390 77.768  1.00 87.54  ? 393 LYS B CB  1 
ATOM   5252  C CG  . LYS B 1 384 ? 100.870 114.830 77.930  1.00 87.54  ? 393 LYS B CG  1 
ATOM   5253  C CD  . LYS B 1 384 ? 102.265 114.910 78.521  1.00 87.54  ? 393 LYS B CD  1 
ATOM   5254  C CE  . LYS B 1 384 ? 103.308 114.452 77.515  1.00 87.54  ? 393 LYS B CE  1 
ATOM   5255  N NZ  . LYS B 1 384 ? 104.680 114.892 77.895  1.00 87.54  ? 393 LYS B NZ  1 
ATOM   5256  N N   . LYS B 1 385 ? 97.956  111.939 79.133  1.00 83.47  ? 394 LYS B N   1 
ATOM   5257  C CA  . LYS B 1 385 ? 96.581  112.004 79.617  1.00 83.47  ? 394 LYS B CA  1 
ATOM   5258  C C   . LYS B 1 385 ? 96.497  111.615 81.087  1.00 83.47  ? 394 LYS B C   1 
ATOM   5259  O O   . LYS B 1 385 ? 95.826  112.285 81.881  1.00 83.47  ? 394 LYS B O   1 
ATOM   5260  C CB  . LYS B 1 385 ? 95.686  111.103 78.765  1.00 83.47  ? 394 LYS B CB  1 
ATOM   5261  C CG  . LYS B 1 385 ? 94.210  111.467 78.808  1.00 83.47  ? 394 LYS B CG  1 
ATOM   5262  C CD  . LYS B 1 385 ? 93.458  110.616 79.817  1.00 83.47  ? 394 LYS B CD  1 
ATOM   5263  C CE  . LYS B 1 385 ? 91.984  110.983 79.858  1.00 83.47  ? 394 LYS B CE  1 
ATOM   5264  N NZ  . LYS B 1 385 ? 91.235  110.157 80.844  1.00 83.47  ? 394 LYS B NZ  1 
ATOM   5265  N N   . ILE B 1 386 ? 97.178  110.533 81.473  1.00 80.15  ? 395 ILE B N   1 
ATOM   5266  C CA  . ILE B 1 386 ? 97.125  110.098 82.865  1.00 80.15  ? 395 ILE B CA  1 
ATOM   5267  C C   . ILE B 1 386 ? 97.854  111.091 83.765  1.00 80.15  ? 395 ILE B C   1 
ATOM   5268  O O   . ILE B 1 386 ? 97.437  111.334 84.903  1.00 80.15  ? 395 ILE B O   1 
ATOM   5269  C CB  . ILE B 1 386 ? 97.668  108.662 83.015  1.00 80.15  ? 395 ILE B CB  1 
ATOM   5270  C CG1 . ILE B 1 386 ? 97.227  108.066 84.354  1.00 80.15  ? 395 ILE B CG1 1 
ATOM   5271  C CG2 . ILE B 1 386 ? 99.183  108.613 82.892  1.00 80.15  ? 395 ILE B CG2 1 
ATOM   5272  C CD1 . ILE B 1 386 ? 95.724  107.985 84.524  1.00 80.15  ? 395 ILE B CD1 1 
ATOM   5273  N N   . ASP B 1 387 ? 98.941  111.694 83.271  1.00 77.06  ? 396 ASP B N   1 
ATOM   5274  C CA  . ASP B 1 387 ? 99.631  112.714 84.052  1.00 77.06  ? 396 ASP B CA  1 
ATOM   5275  C C   . ASP B 1 387 ? 98.733  113.919 84.291  1.00 77.06  ? 396 ASP B C   1 
ATOM   5276  O O   . ASP B 1 387 ? 98.676  114.446 85.406  1.00 77.06  ? 396 ASP B O   1 
ATOM   5277  C CB  . ASP B 1 387 ? 100.920 113.136 83.347  1.00 77.06  ? 396 ASP B CB  1 
ATOM   5278  N N   . THR B 1 388 ? 98.015  114.363 83.257  1.00 78.30  ? 397 THR B N   1 
ATOM   5279  C CA  . THR B 1 388 ? 97.095  115.483 83.425  1.00 78.30  ? 397 THR B CA  1 
ATOM   5280  C C   . THR B 1 388 ? 95.959  115.126 84.376  1.00 78.30  ? 397 THR B C   1 
ATOM   5281  O O   . THR B 1 388 ? 95.571  115.937 85.227  1.00 78.30  ? 397 THR B O   1 
ATOM   5282  C CB  . THR B 1 388 ? 96.539  115.918 82.069  1.00 78.30  ? 397 THR B CB  1 
ATOM   5283  N N   . ILE B 1 389 ? 95.419  113.911 84.254  1.00 78.86  ? 398 ILE B N   1 
ATOM   5284  C CA  . ILE B 1 389 ? 94.323  113.494 85.124  1.00 78.86  ? 398 ILE B CA  1 
ATOM   5285  C C   . ILE B 1 389 ? 94.777  113.468 86.578  1.00 78.86  ? 398 ILE B C   1 
ATOM   5286  O O   . ILE B 1 389 ? 94.072  113.950 87.472  1.00 78.86  ? 398 ILE B O   1 
ATOM   5287  C CB  . ILE B 1 389 ? 93.774  112.127 84.677  1.00 78.86  ? 398 ILE B CB  1 
ATOM   5288  N N   . SER B 1 390 ? 95.964  112.918 86.838  1.00 80.88  ? 399 SER B N   1 
ATOM   5289  C CA  . SER B 1 390 ? 96.452  112.856 88.211  1.00 80.88  ? 399 SER B CA  1 
ATOM   5290  C C   . SER B 1 390 ? 96.843  114.233 88.736  1.00 80.88  ? 399 SER B C   1 
ATOM   5291  O O   . SER B 1 390 ? 96.656  114.513 89.925  1.00 80.88  ? 399 SER B O   1 
ATOM   5292  C CB  . SER B 1 390 ? 97.629  111.886 88.303  1.00 80.88  ? 399 SER B CB  1 
ATOM   5293  N N   . ARG B 1 391 ? 97.374  115.107 87.877  1.00 80.13  ? 400 ARG B N   1 
ATOM   5294  C CA  . ARG B 1 391 ? 97.729  116.453 88.310  1.00 80.13  ? 400 ARG B CA  1 
ATOM   5295  C C   . ARG B 1 391 ? 96.506  117.336 88.500  1.00 80.13  ? 400 ARG B C   1 
ATOM   5296  O O   . ARG B 1 391 ? 96.616  118.399 89.118  1.00 80.13  ? 400 ARG B O   1 
ATOM   5297  C CB  . ARG B 1 391 ? 98.685  117.095 87.304  1.00 80.13  ? 400 ARG B CB  1 
ATOM   5298  N N   . ALA B 1 392 ? 95.356  116.938 87.959  1.00 84.28  ? 401 ALA B N   1 
ATOM   5299  C CA  . ALA B 1 392 ? 94.102  117.608 88.274  1.00 84.28  ? 401 ALA B CA  1 
ATOM   5300  C C   . ALA B 1 392 ? 93.363  116.957 89.435  1.00 84.28  ? 401 ALA B C   1 
ATOM   5301  O O   . ALA B 1 392 ? 92.501  117.600 90.044  1.00 84.28  ? 401 ALA B O   1 
ATOM   5302  C CB  . ALA B 1 392 ? 93.191  117.639 87.043  1.00 84.28  ? 401 ALA B CB  1 
ATOM   5303  N N   . CYS B 1 393 ? 93.672  115.695 89.743  1.00 88.59  ? 402 CYS B N   1 
ATOM   5304  C CA  . CYS B 1 393 ? 93.095  115.040 90.912  1.00 88.59  ? 402 CYS B CA  1 
ATOM   5305  C C   . CYS B 1 393 ? 93.826  115.411 92.197  1.00 88.59  ? 402 CYS B C   1 
ATOM   5306  O O   . CYS B 1 393 ? 93.198  115.493 93.259  1.00 88.59  ? 402 CYS B O   1 
ATOM   5307  C CB  . CYS B 1 393 ? 93.106  113.523 90.718  1.00 88.59  ? 402 CYS B CB  1 
ATOM   5308  S SG  . CYS B 1 393 ? 93.046  112.555 92.244  1.00 88.59  ? 402 CYS B SG  1 
ATOM   5309  N N   . PHE B 1 394 ? 95.139  115.633 92.123  1.00 82.95  ? 403 PHE B N   1 
ATOM   5310  C CA  . PHE B 1 394 ? 95.912  116.049 93.294  1.00 82.95  ? 403 PHE B CA  1 
ATOM   5311  C C   . PHE B 1 394 ? 95.380  117.309 93.966  1.00 82.95  ? 403 PHE B C   1 
ATOM   5312  O O   . PHE B 1 394 ? 95.245  117.305 95.201  1.00 82.95  ? 403 PHE B O   1 
ATOM   5313  C CB  . PHE B 1 394 ? 97.383  116.237 92.895  1.00 82.95  ? 403 PHE B CB  1 
ATOM   5314  C CG  . PHE B 1 394 ? 98.246  115.038 93.168  1.00 82.95  ? 403 PHE B CG  1 
ATOM   5315  C CD1 . PHE B 1 394 ? 97.697  113.770 93.237  1.00 82.95  ? 403 PHE B CD1 1 
ATOM   5316  C CD2 . PHE B 1 394 ? 99.610  115.182 93.356  1.00 82.95  ? 403 PHE B CD2 1 
ATOM   5317  C CE1 . PHE B 1 394 ? 98.493  112.668 93.487  1.00 82.95  ? 403 PHE B CE1 1 
ATOM   5318  C CE2 . PHE B 1 394 ? 100.411 114.085 93.605  1.00 82.95  ? 403 PHE B CE2 1 
ATOM   5319  C CZ  . PHE B 1 394 ? 99.851  112.827 93.672  1.00 82.95  ? 403 PHE B CZ  1 
ATOM   5320  N N   . PRO B 1 395 ? 95.075  118.405 93.254  1.00 83.12  ? 404 PRO B N   1 
ATOM   5321  C CA  . PRO B 1 395 ? 94.536  119.578 93.959  1.00 83.12  ? 404 PRO B CA  1 
ATOM   5322  C C   . PRO B 1 395 ? 93.194  119.324 94.614  1.00 83.12  ? 404 PRO B C   1 
ATOM   5323  O O   . PRO B 1 395 ? 92.978  119.760 95.749  1.00 83.12  ? 404 PRO B O   1 
ATOM   5324  C CB  . PRO B 1 395 ? 94.447  120.640 92.856  1.00 83.12  ? 404 PRO B CB  1 
ATOM   5325  C CG  . PRO B 1 395 ? 94.293  119.874 91.611  1.00 83.12  ? 404 PRO B CG  1 
ATOM   5326  C CD  . PRO B 1 395 ? 95.104  118.624 91.798  1.00 83.12  ? 404 PRO B CD  1 
ATOM   5327  N N   . LEU B 1 396 ? 92.287  118.616 93.937  1.00 86.25  ? 405 LEU B N   1 
ATOM   5328  C CA  . LEU B 1 396 ? 91.002  118.298 94.550  1.00 86.25  ? 405 LEU B CA  1 
ATOM   5329  C C   . LEU B 1 396 ? 91.189  117.453 95.802  1.00 86.25  ? 405 LEU B C   1 
ATOM   5330  O O   . LEU B 1 396 ? 90.572  117.720 96.838  1.00 86.25  ? 405 LEU B O   1 
ATOM   5331  C CB  . LEU B 1 396 ? 90.102  117.580 93.545  1.00 86.25  ? 405 LEU B CB  1 
ATOM   5332  C CG  . LEU B 1 396 ? 89.649  118.383 92.325  1.00 86.25  ? 405 LEU B CG  1 
ATOM   5333  C CD1 . LEU B 1 396 ? 88.754  117.538 91.434  1.00 86.25  ? 405 LEU B CD1 1 
ATOM   5334  C CD2 . LEU B 1 396 ? 88.933  119.656 92.751  1.00 86.25  ? 405 LEU B CD2 1 
ATOM   5335  N N   . ALA B 1 397 ? 92.057  116.441 95.729  1.00 82.65  ? 406 ALA B N   1 
ATOM   5336  C CA  . ALA B 1 397 ? 92.285  115.567 96.877  1.00 82.65  ? 406 ALA B CA  1 
ATOM   5337  C C   . ALA B 1 397 ? 92.880  116.337 98.050  1.00 82.65  ? 406 ALA B C   1 
ATOM   5338  O O   . ALA B 1 397 ? 92.410  116.219 99.188  1.00 82.65  ? 406 ALA B O   1 
ATOM   5339  C CB  . ALA B 1 397 ? 93.196  114.407 96.476  1.00 82.65  ? 406 ALA B CB  1 
ATOM   5340  N N   . PHE B 1 398 ? 93.921  117.131 97.793  1.00 75.04  ? 407 PHE B N   1 
ATOM   5341  C CA  . PHE B 1 398 ? 94.548  117.875 98.880  1.00 75.04  ? 407 PHE B CA  1 
ATOM   5342  C C   . PHE B 1 398 ? 93.591  118.896 99.477  1.00 75.04  ? 407 PHE B C   1 
ATOM   5343  O O   . PHE B 1 398 ? 93.517  119.044 100.702 1.00 75.04  ? 407 PHE B O   1 
ATOM   5344  C CB  . PHE B 1 398 ? 95.823  118.560 98.398  1.00 75.04  ? 407 PHE B CB  1 
ATOM   5345  C CG  . PHE B 1 398 ? 96.717  119.010 99.514  1.00 75.04  ? 407 PHE B CG  1 
ATOM   5346  C CD1 . PHE B 1 398 ? 97.483  118.095 100.214 1.00 75.04  ? 407 PHE B CD1 1 
ATOM   5347  C CD2 . PHE B 1 398 ? 96.785  120.343 99.870  1.00 75.04  ? 407 PHE B CD2 1 
ATOM   5348  C CE1 . PHE B 1 398 ? 98.305  118.502 101.244 1.00 75.04  ? 407 PHE B CE1 1 
ATOM   5349  C CE2 . PHE B 1 398 ? 97.608  120.757 100.899 1.00 75.04  ? 407 PHE B CE2 1 
ATOM   5350  C CZ  . PHE B 1 398 ? 98.367  119.833 101.588 1.00 75.04  ? 407 PHE B CZ  1 
ATOM   5351  N N   . LEU B 1 399 ? 92.846  119.611 98.629  1.00 77.36  ? 408 LEU B N   1 
ATOM   5352  C CA  . LEU B 1 399 ? 91.917  120.612 99.136  1.00 77.36  ? 408 LEU B CA  1 
ATOM   5353  C C   . LEU B 1 399 ? 90.803  119.972 99.951  1.00 77.36  ? 408 LEU B C   1 
ATOM   5354  O O   . LEU B 1 399 ? 90.427  120.493 101.008 1.00 77.36  ? 408 LEU B O   1 
ATOM   5355  C CB  . LEU B 1 399 ? 91.341  121.429 97.979  1.00 77.36  ? 408 LEU B CB  1 
ATOM   5356  C CG  . LEU B 1 399 ? 91.936  122.828 97.798  1.00 77.36  ? 408 LEU B CG  1 
ATOM   5357  C CD1 . LEU B 1 399 ? 93.455  122.773 97.760  1.00 77.36  ? 408 LEU B CD1 1 
ATOM   5358  C CD2 . LEU B 1 399 ? 91.390  123.490 96.542  1.00 77.36  ? 408 LEU B CD2 1 
ATOM   5359  N N   . ILE B 1 400 ? 90.268  118.837 99.489  1.00 79.35  ? 409 ILE B N   1 
ATOM   5360  C CA  . ILE B 1 400 ? 89.192  118.192 100.233 1.00 79.35  ? 409 ILE B CA  1 
ATOM   5361  C C   . ILE B 1 400 ? 89.713  117.639 101.554 1.00 79.35  ? 409 ILE B C   1 
ATOM   5362  O O   . ILE B 1 400 ? 89.045  117.749 102.589 1.00 79.35  ? 409 ILE B O   1 
ATOM   5363  C CB  . ILE B 1 400 ? 88.494  117.115 99.376  1.00 79.35  ? 409 ILE B CB  1 
ATOM   5364  C CG1 . ILE B 1 400 ? 87.133  116.762 99.978  1.00 79.35  ? 409 ILE B CG1 1 
ATOM   5365  C CG2 . ILE B 1 400 ? 89.337  115.858 99.230  1.00 79.35  ? 409 ILE B CG2 1 
ATOM   5366  C CD1 . ILE B 1 400 ? 86.428  115.624 99.272  1.00 79.35  ? 409 ILE B CD1 1 
ATOM   5367  N N   . PHE B 1 401 ? 90.927  117.077 101.558 1.00 73.47  ? 410 PHE B N   1 
ATOM   5368  C CA  . PHE B 1 401 ? 91.501  116.605 102.813 1.00 73.47  ? 410 PHE B CA  1 
ATOM   5369  C C   . PHE B 1 401 ? 91.701  117.755 103.789 1.00 73.47  ? 410 PHE B C   1 
ATOM   5370  O O   . PHE B 1 401 ? 91.371  117.637 104.975 1.00 73.47  ? 410 PHE B O   1 
ATOM   5371  C CB  . PHE B 1 401 ? 92.828  115.891 102.558 1.00 73.47  ? 410 PHE B CB  1 
ATOM   5372  C CG  . PHE B 1 401 ? 93.759  115.914 103.737 1.00 73.47  ? 410 PHE B CG  1 
ATOM   5373  C CD1 . PHE B 1 401 ? 93.477  115.177 104.873 1.00 73.47  ? 410 PHE B CD1 1 
ATOM   5374  C CD2 . PHE B 1 401 ? 94.910  116.680 103.711 1.00 73.47  ? 410 PHE B CD2 1 
ATOM   5375  C CE1 . PHE B 1 401 ? 94.328  115.201 105.959 1.00 73.47  ? 410 PHE B CE1 1 
ATOM   5376  C CE2 . PHE B 1 401 ? 95.765  116.706 104.794 1.00 73.47  ? 410 PHE B CE2 1 
ATOM   5377  C CZ  . PHE B 1 401 ? 95.471  115.968 105.920 1.00 73.47  ? 410 PHE B CZ  1 
ATOM   5378  N N   . ASN B 1 402 ? 92.235  118.880 103.306 1.00 71.43  ? 411 ASN B N   1 
ATOM   5379  C CA  . ASN B 1 402 ? 92.495  120.009 104.190 1.00 71.43  ? 411 ASN B CA  1 
ATOM   5380  C C   . ASN B 1 402 ? 91.201  120.572 104.757 1.00 71.43  ? 411 ASN B C   1 
ATOM   5381  O O   . ASN B 1 402 ? 91.100  120.821 105.965 1.00 71.43  ? 411 ASN B O   1 
ATOM   5382  C CB  . ASN B 1 402 ? 93.275  121.092 103.448 1.00 71.43  ? 411 ASN B CB  1 
ATOM   5383  C CG  . ASN B 1 402 ? 94.769  120.946 103.619 1.00 71.43  ? 411 ASN B CG  1 
ATOM   5384  O OD1 . ASN B 1 402 ? 95.396  121.698 104.363 1.00 71.43  ? 411 ASN B OD1 1 
ATOM   5385  N ND2 . ASN B 1 402 ? 95.350  119.967 102.937 1.00 71.43  ? 411 ASN B ND2 1 
ATOM   5386  N N   . ILE B 1 403 ? 90.193  120.776 103.905 1.00 74.96  ? 412 ILE B N   1 
ATOM   5387  C CA  . ILE B 1 403 ? 88.949  121.347 104.406 1.00 74.96  ? 412 ILE B CA  1 
ATOM   5388  C C   . ILE B 1 403 ? 88.286  120.386 105.383 1.00 74.96  ? 412 ILE B C   1 
ATOM   5389  O O   . ILE B 1 403 ? 87.784  120.807 106.430 1.00 74.96  ? 412 ILE B O   1 
ATOM   5390  C CB  . ILE B 1 403 ? 88.004  121.742 103.254 1.00 74.96  ? 412 ILE B CB  1 
ATOM   5391  C CG1 . ILE B 1 403 ? 86.702  122.317 103.811 1.00 74.96  ? 412 ILE B CG1 1 
ATOM   5392  C CG2 . ILE B 1 403 ? 87.665  120.560 102.383 1.00 74.96  ? 412 ILE B CG2 1 
ATOM   5393  C CD1 . ILE B 1 403 ? 86.795  123.778 104.187 1.00 74.96  ? 412 ILE B CD1 1 
ATOM   5394  N N   . PHE B 1 404 ? 88.306  119.081 105.081 1.00 79.11  ? 413 PHE B N   1 
ATOM   5395  C CA  . PHE B 1 404 ? 87.714  118.092 105.977 1.00 79.11  ? 413 PHE B CA  1 
ATOM   5396  C C   . PHE B 1 404 ? 88.397  118.108 107.340 1.00 79.11  ? 413 PHE B C   1 
ATOM   5397  O O   . PHE B 1 404 ? 87.731  118.166 108.383 1.00 79.11  ? 413 PHE B O   1 
ATOM   5398  C CB  . PHE B 1 404 ? 87.813  116.704 105.338 1.00 79.11  ? 413 PHE B CB  1 
ATOM   5399  C CG  . PHE B 1 404 ? 87.052  115.635 106.069 1.00 79.11  ? 413 PHE B CG  1 
ATOM   5400  C CD1 . PHE B 1 404 ? 85.723  115.385 105.772 1.00 79.11  ? 413 PHE B CD1 1 
ATOM   5401  C CD2 . PHE B 1 404 ? 87.671  114.869 107.044 1.00 79.11  ? 413 PHE B CD2 1 
ATOM   5402  C CE1 . PHE B 1 404 ? 85.021  114.397 106.440 1.00 79.11  ? 413 PHE B CE1 1 
ATOM   5403  C CE2 . PHE B 1 404 ? 86.974  113.881 107.717 1.00 79.11  ? 413 PHE B CE2 1 
ATOM   5404  C CZ  . PHE B 1 404 ? 85.648  113.645 107.414 1.00 79.11  ? 413 PHE B CZ  1 
ATOM   5405  N N   . TYR B 1 405 ? 89.732  118.065 107.345 1.00 66.41  ? 414 TYR B N   1 
ATOM   5406  C CA  . TYR B 1 405 ? 90.484  118.093 108.595 1.00 66.41  ? 414 TYR B CA  1 
ATOM   5407  C C   . TYR B 1 405 ? 90.163  119.348 109.393 1.00 66.41  ? 414 TYR B C   1 
ATOM   5408  O O   . TYR B 1 405 ? 89.883  119.282 110.599 1.00 66.41  ? 414 TYR B O   1 
ATOM   5409  C CB  . TYR B 1 405 ? 91.981  118.008 108.281 1.00 66.41  ? 414 TYR B CB  1 
ATOM   5410  C CG  . TYR B 1 405 ? 92.921  118.201 109.451 1.00 66.41  ? 414 TYR B CG  1 
ATOM   5411  C CD1 . TYR B 1 405 ? 93.313  119.470 109.855 1.00 66.41  ? 414 TYR B CD1 1 
ATOM   5412  C CD2 . TYR B 1 405 ? 93.449  117.112 110.126 1.00 66.41  ? 414 TYR B CD2 1 
ATOM   5413  C CE1 . TYR B 1 405 ? 94.180  119.646 110.912 1.00 66.41  ? 414 TYR B CE1 1 
ATOM   5414  C CE2 . TYR B 1 405 ? 94.321  117.280 111.182 1.00 66.41  ? 414 TYR B CE2 1 
ATOM   5415  C CZ  . TYR B 1 405 ? 94.681  118.548 111.571 1.00 66.41  ? 414 TYR B CZ  1 
ATOM   5416  O OH  . TYR B 1 405 ? 95.547  118.719 112.625 1.00 66.41  ? 414 TYR B OH  1 
ATOM   5417  N N   . TRP B 1 406 ? 90.186  120.505 108.729 1.00 67.40  ? 415 TRP B N   1 
ATOM   5418  C CA  . TRP B 1 406 ? 89.970  121.758 109.439 1.00 67.40  ? 415 TRP B CA  1 
ATOM   5419  C C   . TRP B 1 406 ? 88.572  121.814 110.039 1.00 67.40  ? 415 TRP B C   1 
ATOM   5420  O O   . TRP B 1 406 ? 88.410  122.179 111.208 1.00 67.40  ? 415 TRP B O   1 
ATOM   5421  C CB  . TRP B 1 406 ? 90.214  122.943 108.507 1.00 67.40  ? 415 TRP B CB  1 
ATOM   5422  C CG  . TRP B 1 406 ? 91.668  123.212 108.246 1.00 67.40  ? 415 TRP B CG  1 
ATOM   5423  C CD1 . TRP B 1 406 ? 92.263  123.354 107.028 1.00 67.40  ? 415 TRP B CD1 1 
ATOM   5424  C CD2 . TRP B 1 406 ? 92.710  123.371 109.220 1.00 67.40  ? 415 TRP B CD2 1 
ATOM   5425  N NE1 . TRP B 1 406 ? 93.606  123.589 107.179 1.00 67.40  ? 415 TRP B NE1 1 
ATOM   5426  C CE2 . TRP B 1 406 ? 93.906  123.605 108.515 1.00 67.40  ? 415 TRP B CE2 1 
ATOM   5427  C CE3 . TRP B 1 406 ? 92.747  123.340 110.616 1.00 67.40  ? 415 TRP B CE3 1 
ATOM   5428  C CZ2 . TRP B 1 406 ? 95.124  123.805 109.157 1.00 67.40  ? 415 TRP B CZ2 1 
ATOM   5429  C CZ3 . TRP B 1 406 ? 93.957  123.538 111.251 1.00 67.40  ? 415 TRP B CZ3 1 
ATOM   5430  C CH2 . TRP B 1 406 ? 95.128  123.768 110.522 1.00 67.40  ? 415 TRP B CH2 1 
ATOM   5431  N N   . VAL B 1 407 ? 87.546  121.432 109.270 1.00 73.31  ? 416 VAL B N   1 
ATOM   5432  C CA  . VAL B 1 407 ? 86.195  121.550 109.808 1.00 73.31  ? 416 VAL B CA  1 
ATOM   5433  C C   . VAL B 1 407 ? 86.003  120.577 110.962 1.00 73.31  ? 416 VAL B C   1 
ATOM   5434  O O   . VAL B 1 407 ? 85.443  120.941 112.003 1.00 73.31  ? 416 VAL B O   1 
ATOM   5435  C CB  . VAL B 1 407 ? 85.110  121.342 108.731 1.00 73.31  ? 416 VAL B CB  1 
ATOM   5436  C CG1 . VAL B 1 407 ? 84.885  122.620 107.922 1.00 73.31  ? 416 VAL B CG1 1 
ATOM   5437  C CG2 . VAL B 1 407 ? 85.350  120.109 107.878 1.00 73.31  ? 416 VAL B CG2 1 
ATOM   5438  N N   . ILE B 1 408 ? 86.470  119.332 110.812 1.00 72.35  ? 417 ILE B N   1 
ATOM   5439  C CA  . ILE B 1 408 ? 86.222  118.351 111.864 1.00 72.35  ? 417 ILE B CA  1 
ATOM   5440  C C   . ILE B 1 408 ? 86.921  118.774 113.150 1.00 72.35  ? 417 ILE B C   1 
ATOM   5441  O O   . ILE B 1 408 ? 86.306  118.799 114.223 1.00 72.35  ? 417 ILE B O   1 
ATOM   5442  C CB  . ILE B 1 408 ? 86.627  116.931 111.415 1.00 72.35  ? 417 ILE B CB  1 
ATOM   5443  C CG1 . ILE B 1 408 ? 86.232  115.910 112.481 1.00 72.35  ? 417 ILE B CG1 1 
ATOM   5444  C CG2 . ILE B 1 408 ? 88.113  116.812 111.143 1.00 72.35  ? 417 ILE B CG2 1 
ATOM   5445  C CD1 . ILE B 1 408 ? 86.603  114.489 112.126 1.00 72.35  ? 417 ILE B CD1 1 
ATOM   5446  N N   . TYR B 1 409 ? 88.185  119.201 113.054 1.00 63.14  ? 418 TYR B N   1 
ATOM   5447  C CA  . TYR B 1 409 ? 88.920  119.547 114.263 1.00 63.14  ? 418 TYR B CA  1 
ATOM   5448  C C   . TYR B 1 409 ? 88.561  120.920 114.816 1.00 63.14  ? 418 TYR B C   1 
ATOM   5449  O O   . TYR B 1 409 ? 88.872  121.194 115.979 1.00 63.14  ? 418 TYR B O   1 
ATOM   5450  C CB  . TYR B 1 409 ? 90.425  119.484 114.008 1.00 63.14  ? 418 TYR B CB  1 
ATOM   5451  C CG  . TYR B 1 409 ? 91.038  118.144 114.331 1.00 63.14  ? 418 TYR B CG  1 
ATOM   5452  C CD1 . TYR B 1 409 ? 90.947  117.605 115.604 1.00 63.14  ? 418 TYR B CD1 1 
ATOM   5453  C CD2 . TYR B 1 409 ? 91.721  117.425 113.365 1.00 63.14  ? 418 TYR B CD2 1 
ATOM   5454  C CE1 . TYR B 1 409 ? 91.508  116.380 115.900 1.00 63.14  ? 418 TYR B CE1 1 
ATOM   5455  C CE2 . TYR B 1 409 ? 92.286  116.203 113.653 1.00 63.14  ? 418 TYR B CE2 1 
ATOM   5456  C CZ  . TYR B 1 409 ? 92.178  115.685 114.921 1.00 63.14  ? 418 TYR B CZ  1 
ATOM   5457  O OH  . TYR B 1 409 ? 92.744  114.465 115.206 1.00 63.14  ? 418 TYR B OH  1 
ATOM   5458  N N   . LYS B 1 410 ? 87.908  121.781 114.037 1.00 69.98  ? 419 LYS B N   1 
ATOM   5459  C CA  . LYS B 1 410 ? 87.541  123.101 114.526 1.00 69.98  ? 419 LYS B CA  1 
ATOM   5460  C C   . LYS B 1 410 ? 86.111  123.178 115.036 1.00 69.98  ? 419 LYS B C   1 
ATOM   5461  O O   . LYS B 1 410 ? 85.809  124.045 115.862 1.00 69.98  ? 419 LYS B O   1 
ATOM   5462  C CB  . LYS B 1 410 ? 87.730  124.146 113.420 1.00 69.98  ? 419 LYS B CB  1 
ATOM   5463  C CG  . LYS B 1 410 ? 88.223  125.499 113.908 1.00 69.98  ? 419 LYS B CG  1 
ATOM   5464  C CD  . LYS B 1 410 ? 89.728  125.502 114.116 1.00 69.98  ? 419 LYS B CD  1 
ATOM   5465  C CE  . LYS B 1 410 ? 90.282  126.916 114.095 1.00 69.98  ? 419 LYS B CE  1 
ATOM   5466  N NZ  . LYS B 1 410 ? 91.770  126.935 114.091 1.00 69.98  ? 419 LYS B NZ  1 
ATOM   5467  N N   . ILE B 1 411 ? 85.223  122.298 114.572 1.00 82.83  ? 420 ILE B N   1 
ATOM   5468  C CA  . ILE B 1 411 ? 83.820  122.312 114.964 1.00 82.83  ? 420 ILE B CA  1 
ATOM   5469  C C   . ILE B 1 411 ? 83.409  120.999 115.620 1.00 82.83  ? 420 ILE B C   1 
ATOM   5470  O O   . ILE B 1 411 ? 82.858  120.990 116.725 1.00 82.83  ? 420 ILE B O   1 
ATOM   5471  C CB  . ILE B 1 411 ? 82.905  122.629 113.760 1.00 82.83  ? 420 ILE B CB  1 
ATOM   5472  C CG1 . ILE B 1 411 ? 83.323  123.951 113.112 1.00 82.83  ? 420 ILE B CG1 1 
ATOM   5473  C CG2 . ILE B 1 411 ? 81.453  122.683 114.198 1.00 82.83  ? 420 ILE B CG2 1 
ATOM   5474  C CD1 . ILE B 1 411 ? 82.538  124.299 111.868 1.00 82.83  ? 420 ILE B CD1 1 
ATOM   5475  N N   . LEU B 1 412 ? 83.670  119.873 114.952 1.00 88.41  ? 421 LEU B N   1 
ATOM   5476  C CA  . LEU B 1 412 ? 83.207  118.596 115.478 1.00 88.41  ? 421 LEU B CA  1 
ATOM   5477  C C   . LEU B 1 412 ? 84.041  118.133 116.665 1.00 88.41  ? 421 LEU B C   1 
ATOM   5478  O O   . LEU B 1 412 ? 83.512  117.483 117.572 1.00 88.41  ? 421 LEU B O   1 
ATOM   5479  C CB  . LEU B 1 412 ? 83.222  117.535 114.376 1.00 88.41  ? 421 LEU B CB  1 
ATOM   5480  C CG  . LEU B 1 412 ? 82.310  116.324 114.584 1.00 88.41  ? 421 LEU B CG  1 
ATOM   5481  C CD1 . LEU B 1 412 ? 80.850  116.750 114.613 1.00 88.41  ? 421 LEU B CD1 1 
ATOM   5482  C CD2 . LEU B 1 412 ? 82.545  115.278 113.506 1.00 88.41  ? 421 LEU B CD2 1 
ATOM   5483  N N   . ARG B 1 413 ? 85.330  118.457 116.680 1.00 74.93  ? 422 ARG B N   1 
ATOM   5484  C CA  . ARG B 1 413 ? 86.212  118.034 117.757 1.00 74.93  ? 422 ARG B CA  1 
ATOM   5485  C C   . ARG B 1 413 ? 86.708  119.232 118.558 1.00 74.93  ? 422 ARG B C   1 
ATOM   5486  O O   . ARG B 1 413 ? 86.195  120.342 118.414 1.00 74.93  ? 422 ARG B O   1 
ATOM   5487  C CB  . ARG B 1 413 ? 87.397  117.246 117.198 1.00 74.93  ? 422 ARG B CB  1 
ATOM   5488  C CG  . ARG B 1 413 ? 87.008  116.161 116.207 1.00 74.93  ? 422 ARG B CG  1 
ATOM   5489  C CD  . ARG B 1 413 ? 86.592  114.883 116.914 1.00 74.93  ? 422 ARG B CD  1 
ATOM   5490  N NE  . ARG B 1 413 ? 87.635  114.377 117.799 1.00 74.93  ? 422 ARG B NE  1 
ATOM   5491  C CZ  . ARG B 1 413 ? 88.422  113.348 117.519 1.00 74.93  ? 422 ARG B CZ  1 
ATOM   5492  N NH1 . ARG B 1 413 ? 88.319  112.688 116.377 1.00 74.93  ? 422 ARG B NH1 1 
ATOM   5493  N NH2 . ARG B 1 413 ? 89.335  112.969 118.408 1.00 74.93  ? 422 ARG B NH2 1 
ATOM   5494  N N   . MET C 1 8   ? 89.566  117.167 183.088 1.00 101.00 ? 8   MET C N   1 
ATOM   5495  C CA  . MET C 1 8   ? 88.583  117.215 182.012 1.00 101.00 ? 8   MET C CA  1 
ATOM   5496  C C   . MET C 1 8   ? 89.044  118.149 180.900 1.00 101.00 ? 8   MET C C   1 
ATOM   5497  O O   . MET C 1 8   ? 88.638  118.003 179.747 1.00 101.00 ? 8   MET C O   1 
ATOM   5498  C CB  . MET C 1 8   ? 87.221  117.665 182.546 1.00 101.00 ? 8   MET C CB  1 
ATOM   5499  C CG  . MET C 1 8   ? 86.755  116.907 183.778 1.00 101.00 ? 8   MET C CG  1 
ATOM   5500  S SD  . MET C 1 8   ? 87.808  117.196 185.212 1.00 101.00 ? 8   MET C SD  1 
ATOM   5501  C CE  . MET C 1 8   ? 87.713  118.979 185.350 1.00 101.00 ? 8   MET C CE  1 
ATOM   5502  N N   . SER C 1 9   ? 89.889  119.108 181.256 1.00 88.78  ? 9   SER C N   1 
ATOM   5503  C CA  . SER C 1 9   ? 90.402  120.053 180.272 1.00 88.78  ? 9   SER C CA  1 
ATOM   5504  C C   . SER C 1 9   ? 91.297  119.325 179.275 1.00 88.78  ? 9   SER C C   1 
ATOM   5505  O O   . SER C 1 9   ? 92.150  118.528 179.685 1.00 88.78  ? 9   SER C O   1 
ATOM   5506  C CB  . SER C 1 9   ? 91.175  121.173 180.960 1.00 88.78  ? 9   SER C CB  1 
ATOM   5507  O OG  . SER C 1 9   ? 91.662  122.107 180.013 1.00 88.78  ? 9   SER C OG  1 
ATOM   5508  N N   . PRO C 1 10  ? 91.132  119.558 177.971 1.00 75.23  ? 10  PRO C N   1 
ATOM   5509  C CA  . PRO C 1 10  ? 91.954  118.834 176.989 1.00 75.23  ? 10  PRO C CA  1 
ATOM   5510  C C   . PRO C 1 10  ? 93.442  119.083 177.142 1.00 75.23  ? 10  PRO C C   1 
ATOM   5511  O O   . PRO C 1 10  ? 94.239  118.168 176.902 1.00 75.23  ? 10  PRO C O   1 
ATOM   5512  C CB  . PRO C 1 10  ? 91.427  119.353 175.645 1.00 75.23  ? 10  PRO C CB  1 
ATOM   5513  C CG  . PRO C 1 10  ? 90.832  120.681 175.963 1.00 75.23  ? 10  PRO C CG  1 
ATOM   5514  C CD  . PRO C 1 10  ? 90.247  120.545 177.334 1.00 75.23  ? 10  PRO C CD  1 
ATOM   5515  N N   . SER C 1 11  ? 93.843  120.294 177.531 1.00 74.30  ? 11  SER C N   1 
ATOM   5516  C CA  . SER C 1 11  ? 95.258  120.558 177.768 1.00 74.30  ? 11  SER C CA  1 
ATOM   5517  C C   . SER C 1 11  ? 95.784  119.710 178.918 1.00 74.30  ? 11  SER C C   1 
ATOM   5518  O O   . SER C 1 11  ? 96.894  119.168 178.844 1.00 74.30  ? 11  SER C O   1 
ATOM   5519  C CB  . SER C 1 11  ? 95.476  122.044 178.051 1.00 74.30  ? 11  SER C CB  1 
ATOM   5520  O OG  . SER C 1 11  ? 96.852  122.334 178.220 1.00 74.30  ? 11  SER C OG  1 
ATOM   5521  N N   . ASP C 1 12  ? 94.997  119.582 179.987 1.00 79.99  ? 12  ASP C N   1 
ATOM   5522  C CA  . ASP C 1 12  ? 95.405  118.751 181.113 1.00 79.99  ? 12  ASP C CA  1 
ATOM   5523  C C   . ASP C 1 12  ? 95.542  117.296 180.683 1.00 79.99  ? 12  ASP C C   1 
ATOM   5524  O O   . ASP C 1 12  ? 96.496  116.614 181.070 1.00 79.99  ? 12  ASP C O   1 
ATOM   5525  C CB  . ASP C 1 12  ? 94.393  118.898 182.253 1.00 79.99  ? 12  ASP C CB  1 
ATOM   5526  C CG  . ASP C 1 12  ? 94.780  118.125 183.508 1.00 79.99  ? 12  ASP C CG  1 
ATOM   5527  O OD1 . ASP C 1 12  ? 95.817  117.430 183.518 1.00 79.99  ? 12  ASP C OD1 1 
ATOM   5528  O OD2 . ASP C 1 12  ? 94.031  118.217 184.503 1.00 79.99  ? 12  ASP C OD2 1 
ATOM   5529  N N   . PHE C 1 13  ? 94.604  116.807 179.867 1.00 73.26  ? 13  PHE C N   1 
ATOM   5530  C CA  . PHE C 1 13  ? 94.684  115.433 179.381 1.00 73.26  ? 13  PHE C CA  1 
ATOM   5531  C C   . PHE C 1 13  ? 95.921  115.218 178.517 1.00 73.26  ? 13  PHE C C   1 
ATOM   5532  O O   . PHE C 1 13  ? 96.620  114.205 178.656 1.00 73.26  ? 13  PHE C O   1 
ATOM   5533  C CB  . PHE C 1 13  ? 93.414  115.088 178.604 1.00 73.26  ? 13  PHE C CB  1 
ATOM   5534  C CG  . PHE C 1 13  ? 93.548  113.887 177.716 1.00 73.26  ? 13  PHE C CG  1 
ATOM   5535  C CD1 . PHE C 1 13  ? 93.341  112.616 178.218 1.00 73.26  ? 13  PHE C CD1 1 
ATOM   5536  C CD2 . PHE C 1 13  ? 93.855  114.031 176.374 1.00 73.26  ? 13  PHE C CD2 1 
ATOM   5537  C CE1 . PHE C 1 13  ? 93.456  111.511 177.404 1.00 73.26  ? 13  PHE C CE1 1 
ATOM   5538  C CE2 . PHE C 1 13  ? 93.973  112.930 175.557 1.00 73.26  ? 13  PHE C CE2 1 
ATOM   5539  C CZ  . PHE C 1 13  ? 93.771  111.669 176.071 1.00 73.26  ? 13  PHE C CZ  1 
ATOM   5540  N N   . LEU C 1 14  ? 96.207  116.162 177.617 1.00 65.98  ? 14  LEU C N   1 
ATOM   5541  C CA  . LEU C 1 14  ? 97.394  116.048 176.777 1.00 65.98  ? 14  LEU C CA  1 
ATOM   5542  C C   . LEU C 1 14  ? 98.662  116.049 177.618 1.00 65.98  ? 14  LEU C C   1 
ATOM   5543  O O   . LEU C 1 14  ? 99.594  115.282 177.350 1.00 65.98  ? 14  LEU C O   1 
ATOM   5544  C CB  . LEU C 1 14  ? 97.429  117.187 175.759 1.00 65.98  ? 14  LEU C CB  1 
ATOM   5545  C CG  . LEU C 1 14  ? 97.050  116.835 174.322 1.00 65.98  ? 14  LEU C CG  1 
ATOM   5546  C CD1 . LEU C 1 14  ? 98.065  115.872 173.737 1.00 65.98  ? 14  LEU C CD1 1 
ATOM   5547  C CD2 . LEU C 1 14  ? 95.652  116.251 174.263 1.00 65.98  ? 14  LEU C CD2 1 
ATOM   5548  N N   . ASP C 1 15  ? 98.718  116.906 178.638 1.00 69.01  ? 15  ASP C N   1 
ATOM   5549  C CA  . ASP C 1 15  ? 99.880  116.932 179.517 1.00 69.01  ? 15  ASP C CA  1 
ATOM   5550  C C   . ASP C 1 15  ? 100.005 115.635 180.308 1.00 69.01  ? 15  ASP C C   1 
ATOM   5551  O O   . ASP C 1 15  ? 101.116 115.156 180.557 1.00 69.01  ? 15  ASP C O   1 
ATOM   5552  C CB  . ASP C 1 15  ? 99.799  118.134 180.456 1.00 69.01  ? 15  ASP C CB  1 
ATOM   5553  C CG  . ASP C 1 15  ? 99.885  119.453 179.717 1.00 69.01  ? 15  ASP C CG  1 
ATOM   5554  O OD1 . ASP C 1 15  ? 99.850  119.439 178.468 1.00 69.01  ? 15  ASP C OD1 1 
ATOM   5555  O OD2 . ASP C 1 15  ? 99.987  120.504 180.383 1.00 69.01  ? 15  ASP C OD2 1 
ATOM   5556  N N   . LYS C 1 16  ? 98.878  115.055 180.714 1.00 65.28  ? 16  LYS C N   1 
ATOM   5557  C CA  . LYS C 1 16  ? 98.904  113.827 181.494 1.00 65.28  ? 16  LYS C CA  1 
ATOM   5558  C C   . LYS C 1 16  ? 99.199  112.597 180.648 1.00 65.28  ? 16  LYS C C   1 
ATOM   5559  O O   . LYS C 1 16  ? 99.581  111.561 181.203 1.00 65.28  ? 16  LYS C O   1 
ATOM   5560  C CB  . LYS C 1 16  ? 97.573  113.642 182.225 1.00 65.28  ? 16  LYS C CB  1 
ATOM   5561  C CG  . LYS C 1 16  ? 97.638  112.701 183.415 1.00 65.28  ? 16  LYS C CG  1 
ATOM   5562  C CD  . LYS C 1 16  ? 96.312  112.660 184.154 1.00 65.28  ? 16  LYS C CD  1 
ATOM   5563  C CE  . LYS C 1 16  ? 95.190  112.187 183.248 1.00 65.28  ? 16  LYS C CE  1 
ATOM   5564  N NZ  . LYS C 1 16  ? 93.883  112.174 183.959 1.00 65.28  ? 16  LYS C NZ  1 
ATOM   5565  N N   . LEU C 1 17  ? 99.035  112.679 179.328 1.00 64.69  ? 17  LEU C N   1 
ATOM   5566  C CA  . LEU C 1 17  ? 99.277  111.527 178.464 1.00 64.69  ? 17  LEU C CA  1 
ATOM   5567  C C   . LEU C 1 17  ? 100.652 111.571 177.801 1.00 64.69  ? 17  LEU C C   1 
ATOM   5568  O O   . LEU C 1 17  ? 101.448 110.643 177.966 1.00 64.69  ? 17  LEU C O   1 
ATOM   5569  C CB  . LEU C 1 17  ? 98.170  111.425 177.410 1.00 64.69  ? 17  LEU C CB  1 
ATOM   5570  C CG  . LEU C 1 17  ? 97.790  109.987 177.063 1.00 64.69  ? 17  LEU C CG  1 
ATOM   5571  C CD1 . LEU C 1 17  ? 97.191  109.294 178.273 1.00 64.69  ? 17  LEU C CD1 1 
ATOM   5572  C CD2 . LEU C 1 17  ? 96.832  109.954 175.888 1.00 64.69  ? 17  LEU C CD2 1 
ATOM   5573  N N   . MET C 1 18  ? 100.948 112.631 177.045 1.00 62.11  ? 18  MET C N   1 
ATOM   5574  C CA  . MET C 1 18  ? 102.261 112.801 176.435 1.00 62.11  ? 18  MET C CA  1 
ATOM   5575  C C   . MET C 1 18  ? 103.070 113.951 177.017 1.00 62.11  ? 18  MET C C   1 
ATOM   5576  O O   . MET C 1 18  ? 104.255 114.074 176.691 1.00 62.11  ? 18  MET C O   1 
ATOM   5577  C CB  . MET C 1 18  ? 102.143 113.019 174.916 1.00 62.11  ? 18  MET C CB  1 
ATOM   5578  C CG  . MET C 1 18  ? 101.684 111.823 174.097 1.00 62.11  ? 18  MET C CG  1 
ATOM   5579  S SD  . MET C 1 18  ? 100.125 111.081 174.586 1.00 62.11  ? 18  MET C SD  1 
ATOM   5580  C CE  . MET C 1 18  ? 98.966  112.247 173.885 1.00 62.11  ? 18  MET C CE  1 
ATOM   5581  N N   . GLY C 1 19  ? 102.478 114.787 177.864 1.00 68.73  ? 19  GLY C N   1 
ATOM   5582  C CA  . GLY C 1 19  ? 103.125 116.000 178.314 1.00 68.73  ? 19  GLY C CA  1 
ATOM   5583  C C   . GLY C 1 19  ? 104.220 115.745 179.332 1.00 68.73  ? 19  GLY C C   1 
ATOM   5584  O O   . GLY C 1 19  ? 104.611 114.611 179.615 1.00 68.73  ? 19  GLY C O   1 
ATOM   5585  N N   . ARG C 1 20  ? 104.731 116.848 179.884 1.00 71.23  ? 20  ARG C N   1 
ATOM   5586  C CA  . ARG C 1 20  ? 105.840 116.762 180.830 1.00 71.23  ? 20  ARG C CA  1 
ATOM   5587  C C   . ARG C 1 20  ? 105.437 116.017 182.097 1.00 71.23  ? 20  ARG C C   1 
ATOM   5588  O O   . ARG C 1 20  ? 106.196 115.181 182.601 1.00 71.23  ? 20  ARG C O   1 
ATOM   5589  C CB  . ARG C 1 20  ? 106.346 118.163 181.170 1.00 71.23  ? 20  ARG C CB  1 
ATOM   5590  N N   . THR C 1 21  ? 104.247 116.304 182.625 1.00 69.36  ? 21  THR C N   1 
ATOM   5591  C CA  . THR C 1 21  ? 103.785 115.632 183.834 1.00 69.36  ? 21  THR C CA  1 
ATOM   5592  C C   . THR C 1 21  ? 103.383 114.185 183.588 1.00 69.36  ? 21  THR C C   1 
ATOM   5593  O O   . THR C 1 21  ? 103.162 113.450 184.557 1.00 69.36  ? 21  THR C O   1 
ATOM   5594  C CB  . THR C 1 21  ? 102.604 116.390 184.443 1.00 69.36  ? 21  THR C CB  1 
ATOM   5595  O OG1 . THR C 1 21  ? 102.004 115.594 185.472 1.00 69.36  ? 21  THR C OG1 1 
ATOM   5596  C CG2 . THR C 1 21  ? 101.565 116.699 183.378 1.00 69.36  ? 21  THR C CG2 1 
ATOM   5597  N N   . SER C 1 22  ? 103.277 113.765 182.327 1.00 69.21  ? 22  SER C N   1 
ATOM   5598  C CA  . SER C 1 22  ? 102.875 112.395 182.031 1.00 69.21  ? 22  SER C CA  1 
ATOM   5599  C C   . SER C 1 22  ? 103.911 111.392 182.517 1.00 69.21  ? 22  SER C C   1 
ATOM   5600  O O   . SER C 1 22  ? 103.560 110.335 183.054 1.00 69.21  ? 22  SER C O   1 
ATOM   5601  C CB  . SER C 1 22  ? 102.645 112.231 180.530 1.00 69.21  ? 22  SER C CB  1 
ATOM   5602  O OG  . SER C 1 22  ? 103.828 112.507 179.802 1.00 69.21  ? 22  SER C OG  1 
ATOM   5603  N N   . GLY C 1 23  ? 105.191 111.703 182.337 1.00 65.99  ? 23  GLY C N   1 
ATOM   5604  C CA  . GLY C 1 23  ? 106.241 110.745 182.592 1.00 65.99  ? 23  GLY C CA  1 
ATOM   5605  C C   . GLY C 1 23  ? 106.498 109.783 181.456 1.00 65.99  ? 23  GLY C C   1 
ATOM   5606  O O   . GLY C 1 23  ? 107.389 108.933 181.575 1.00 65.99  ? 23  GLY C O   1 
ATOM   5607  N N   . TYR C 1 24  ? 105.746 109.886 180.364 1.00 58.68  ? 24  TYR C N   1 
ATOM   5608  C CA  . TYR C 1 24  ? 105.980 109.041 179.203 1.00 58.68  ? 24  TYR C CA  1 
ATOM   5609  C C   . TYR C 1 24  ? 107.284 109.437 178.528 1.00 58.68  ? 24  TYR C C   1 
ATOM   5610  O O   . TYR C 1 24  ? 107.456 110.586 178.111 1.00 58.68  ? 24  TYR C O   1 
ATOM   5611  C CB  . TYR C 1 24  ? 104.817 109.165 178.221 1.00 58.68  ? 24  TYR C CB  1 
ATOM   5612  C CG  . TYR C 1 24  ? 105.027 108.431 176.918 1.00 58.68  ? 24  TYR C CG  1 
ATOM   5613  C CD1 . TYR C 1 24  ? 104.825 107.063 176.832 1.00 58.68  ? 24  TYR C CD1 1 
ATOM   5614  C CD2 . TYR C 1 24  ? 105.421 109.107 175.772 1.00 58.68  ? 24  TYR C CD2 1 
ATOM   5615  C CE1 . TYR C 1 24  ? 105.012 106.387 175.646 1.00 58.68  ? 24  TYR C CE1 1 
ATOM   5616  C CE2 . TYR C 1 24  ? 105.610 108.438 174.581 1.00 58.68  ? 24  TYR C CE2 1 
ATOM   5617  C CZ  . TYR C 1 24  ? 105.404 107.077 174.524 1.00 58.68  ? 24  TYR C CZ  1 
ATOM   5618  O OH  . TYR C 1 24  ? 105.590 106.398 173.343 1.00 58.68  ? 24  TYR C OH  1 
ATOM   5619  N N   . ASP C 1 25  ? 108.203 108.484 178.414 1.00 58.14  ? 25  ASP C N   1 
ATOM   5620  C CA  . ASP C 1 25  ? 109.495 108.718 177.783 1.00 58.14  ? 25  ASP C CA  1 
ATOM   5621  C C   . ASP C 1 25  ? 109.429 108.195 176.354 1.00 58.14  ? 25  ASP C C   1 
ATOM   5622  O O   . ASP C 1 25  ? 109.471 106.981 176.127 1.00 58.14  ? 25  ASP C O   1 
ATOM   5623  C CB  . ASP C 1 25  ? 110.618 108.042 178.564 1.00 58.14  ? 25  ASP C CB  1 
ATOM   5624  C CG  . ASP C 1 25  ? 111.968 108.665 178.291 1.00 58.14  ? 25  ASP C CG  1 
ATOM   5625  O OD1 . ASP C 1 25  ? 112.108 109.344 177.253 1.00 58.14  ? 25  ASP C OD1 1 
ATOM   5626  O OD2 . ASP C 1 25  ? 112.891 108.477 179.108 1.00 58.14  ? 25  ASP C OD2 1 
ATOM   5627  N N   . ALA C 1 26  ? 109.339 109.111 175.392 1.00 55.34  ? 26  ALA C N   1 
ATOM   5628  C CA  . ALA C 1 26  ? 109.295 108.733 173.986 1.00 55.34  ? 26  ALA C CA  1 
ATOM   5629  C C   . ALA C 1 26  ? 110.636 108.252 173.466 1.00 55.34  ? 26  ALA C C   1 
ATOM   5630  O O   . ALA C 1 26  ? 110.743 107.929 172.278 1.00 55.34  ? 26  ALA C O   1 
ATOM   5631  C CB  . ALA C 1 26  ? 108.810 109.910 173.141 1.00 55.34  ? 26  ALA C CB  1 
ATOM   5632  N N   . ARG C 1 27  ? 111.653 108.201 174.316 1.00 55.00  ? 27  ARG C N   1 
ATOM   5633  C CA  . ARG C 1 27  ? 113.003 107.846 173.917 1.00 55.00  ? 27  ARG C CA  1 
ATOM   5634  C C   . ARG C 1 27  ? 113.301 106.365 174.102 1.00 55.00  ? 27  ARG C C   1 
ATOM   5635  O O   . ARG C 1 27  ? 114.437 105.942 173.869 1.00 55.00  ? 27  ARG C O   1 
ATOM   5636  C CB  . ARG C 1 27  ? 113.998 108.691 174.714 1.00 55.00  ? 27  ARG C CB  1 
ATOM   5637  C CG  . ARG C 1 27  ? 115.222 109.137 173.949 1.00 55.00  ? 27  ARG C CG  1 
ATOM   5638  C CD  . ARG C 1 27  ? 116.049 110.142 174.753 1.00 55.00  ? 27  ARG C CD  1 
ATOM   5639  N NE  . ARG C 1 27  ? 115.940 109.968 176.198 1.00 55.00  ? 27  ARG C NE  1 
ATOM   5640  C CZ  . ARG C 1 27  ? 115.161 110.694 176.988 1.00 55.00  ? 27  ARG C CZ  1 
ATOM   5641  N NH1 . ARG C 1 27  ? 114.395 111.658 176.506 1.00 55.00  ? 27  ARG C NH1 1 
ATOM   5642  N NH2 . ARG C 1 27  ? 115.149 110.444 178.294 1.00 55.00  ? 27  ARG C NH2 1 
ATOM   5643  N N   . ILE C 1 28  ? 112.315 105.574 174.518 1.00 52.38  ? 28  ILE C N   1 
ATOM   5644  C CA  . ILE C 1 28  ? 112.480 104.144 174.743 1.00 52.38  ? 28  ILE C CA  1 
ATOM   5645  C C   . ILE C 1 28  ? 111.294 103.413 174.128 1.00 52.38  ? 28  ILE C C   1 
ATOM   5646  O O   . ILE C 1 28  ? 110.146 103.847 174.267 1.00 52.38  ? 28  ILE C O   1 
ATOM   5647  C CB  . ILE C 1 28  ? 112.610 103.822 176.246 1.00 52.38  ? 28  ILE C CB  1 
ATOM   5648  C CG1 . ILE C 1 28  ? 112.591 102.313 176.480 1.00 52.38  ? 28  ILE C CG1 1 
ATOM   5649  C CG2 . ILE C 1 28  ? 111.506 104.499 177.039 1.00 52.38  ? 28  ILE C CG2 1 
ATOM   5650  C CD1 . ILE C 1 28  ? 112.851 101.931 177.908 1.00 52.38  ? 28  ILE C CD1 1 
ATOM   5651  N N   . ARG C 1 29  ? 111.574 102.307 173.445 1.00 51.82  ? 29  ARG C N   1 
ATOM   5652  C CA  . ARG C 1 29  ? 110.527 101.570 172.759 1.00 51.82  ? 29  ARG C CA  1 
ATOM   5653  C C   . ARG C 1 29  ? 109.579 100.917 173.765 1.00 51.82  ? 29  ARG C C   1 
ATOM   5654  O O   . ARG C 1 29  ? 109.969 100.625 174.898 1.00 51.82  ? 29  ARG C O   1 
ATOM   5655  C CB  . ARG C 1 29  ? 111.134 100.502 171.852 1.00 51.82  ? 29  ARG C CB  1 
ATOM   5656  C CG  . ARG C 1 29  ? 111.749 99.332  172.591 1.00 51.82  ? 29  ARG C CG  1 
ATOM   5657  C CD  . ARG C 1 29  ? 111.965 98.158  171.657 1.00 51.82  ? 29  ARG C CD  1 
ATOM   5658  N NE  . ARG C 1 29  ? 112.366 96.957  172.377 1.00 51.82  ? 29  ARG C NE  1 
ATOM   5659  C CZ  . ARG C 1 29  ? 111.524 96.146  173.001 1.00 51.82  ? 29  ARG C CZ  1 
ATOM   5660  N NH1 . ARG C 1 29  ? 110.222 96.378  173.013 1.00 51.82  ? 29  ARG C NH1 1 
ATOM   5661  N NH2 . ARG C 1 29  ? 112.000 95.074  173.629 1.00 51.82  ? 29  ARG C NH2 1 
ATOM   5662  N N   . PRO C 1 30  ? 108.324 100.690 173.380 1.00 49.48  ? 30  PRO C N   1 
ATOM   5663  C CA  . PRO C 1 30  ? 107.392 100.008 174.281 1.00 49.48  ? 30  PRO C CA  1 
ATOM   5664  C C   . PRO C 1 30  ? 107.793 98.561  174.504 1.00 49.48  ? 30  PRO C C   1 
ATOM   5665  O O   . PRO C 1 30  ? 108.434 97.932  173.659 1.00 49.48  ? 30  PRO C O   1 
ATOM   5666  C CB  . PRO C 1 30  ? 106.053 100.102 173.542 1.00 49.48  ? 30  PRO C CB  1 
ATOM   5667  C CG  . PRO C 1 30  ? 106.433 100.212 172.116 1.00 49.48  ? 30  PRO C CG  1 
ATOM   5668  C CD  . PRO C 1 30  ? 107.686 101.036 172.099 1.00 49.48  ? 30  PRO C CD  1 
ATOM   5669  N N   . ASN C 1 31  ? 107.399 98.037  175.665 1.00 55.65  ? 31  ASN C N   1 
ATOM   5670  C CA  . ASN C 1 31  ? 107.712 96.664  176.063 1.00 55.65  ? 31  ASN C CA  1 
ATOM   5671  C C   . ASN C 1 31  ? 109.219 96.415  176.035 1.00 55.65  ? 31  ASN C C   1 
ATOM   5672  O O   . ASN C 1 31  ? 109.696 95.414  175.497 1.00 55.65  ? 31  ASN C O   1 
ATOM   5673  C CB  . ASN C 1 31  ? 106.975 95.651  175.184 1.00 55.65  ? 31  ASN C CB  1 
ATOM   5674  C CG  . ASN C 1 31  ? 105.512 95.989  175.010 1.00 55.65  ? 31  ASN C CG  1 
ATOM   5675  O OD1 . ASN C 1 31  ? 105.159 96.885  174.246 1.00 55.65  ? 31  ASN C OD1 1 
ATOM   5676  N ND2 . ASN C 1 31  ? 104.649 95.267  175.714 1.00 55.65  ? 31  ASN C ND2 1 
ATOM   5677  N N   . PHE C 1 32  ? 109.972 97.347  176.614 1.00 62.10  ? 32  PHE C N   1 
ATOM   5678  C CA  . PHE C 1 32  ? 111.419 97.197  176.667 1.00 62.10  ? 32  PHE C CA  1 
ATOM   5679  C C   . PHE C 1 32  ? 111.790 95.985  177.509 1.00 62.10  ? 32  PHE C C   1 
ATOM   5680  O O   . PHE C 1 32  ? 111.153 95.695  178.526 1.00 62.10  ? 32  PHE C O   1 
ATOM   5681  C CB  . PHE C 1 32  ? 112.067 98.455  177.238 1.00 62.10  ? 32  PHE C CB  1 
ATOM   5682  C CG  . PHE C 1 32  ? 113.563 98.464  177.131 1.00 62.10  ? 32  PHE C CG  1 
ATOM   5683  C CD1 . PHE C 1 32  ? 114.185 98.203  175.924 1.00 62.10  ? 32  PHE C CD1 1 
ATOM   5684  C CD2 . PHE C 1 32  ? 114.349 98.735  178.237 1.00 62.10  ? 32  PHE C CD2 1 
ATOM   5685  C CE1 . PHE C 1 32  ? 115.562 98.210  175.821 1.00 62.10  ? 32  PHE C CE1 1 
ATOM   5686  C CE2 . PHE C 1 32  ? 115.727 98.744  178.140 1.00 62.10  ? 32  PHE C CE2 1 
ATOM   5687  C CZ  . PHE C 1 32  ? 116.333 98.481  176.930 1.00 62.10  ? 32  PHE C CZ  1 
ATOM   5688  N N   . LYS C 1 33  ? 112.831 95.273  177.073 1.00 65.74  ? 33  LYS C N   1 
ATOM   5689  C CA  . LYS C 1 33  ? 113.233 94.005  177.683 1.00 65.74  ? 33  LYS C CA  1 
ATOM   5690  C C   . LYS C 1 33  ? 112.074 93.011  177.682 1.00 65.74  ? 33  LYS C C   1 
ATOM   5691  O O   . LYS C 1 33  ? 111.886 92.244  178.629 1.00 65.74  ? 33  LYS C O   1 
ATOM   5692  C CB  . LYS C 1 33  ? 113.775 94.212  179.099 1.00 65.74  ? 33  LYS C CB  1 
ATOM   5693  C CG  . LYS C 1 33  ? 114.975 95.139  179.174 1.00 65.74  ? 33  LYS C CG  1 
ATOM   5694  C CD  . LYS C 1 33  ? 116.267 94.399  178.871 1.00 65.74  ? 33  LYS C CD  1 
ATOM   5695  C CE  . LYS C 1 33  ? 117.478 95.271  179.158 1.00 65.74  ? 33  LYS C CE  1 
ATOM   5696  N NZ  . LYS C 1 33  ? 118.757 94.524  179.013 1.00 65.74  ? 33  LYS C NZ  1 
ATOM   5697  N N   . GLY C 1 34  ? 111.289 93.027  176.608 1.00 59.43  ? 34  GLY C N   1 
ATOM   5698  C CA  . GLY C 1 34  ? 110.148 92.154  176.481 1.00 59.43  ? 34  GLY C CA  1 
ATOM   5699  C C   . GLY C 1 34  ? 109.960 91.664  175.060 1.00 59.43  ? 34  GLY C C   1 
ATOM   5700  O O   . GLY C 1 34  ? 110.882 91.697  174.240 1.00 59.43  ? 34  GLY C O   1 
ATOM   5701  N N   . PRO C 1 35  ? 108.756 91.190  174.746 1.00 55.27  ? 35  PRO C N   1 
ATOM   5702  C CA  . PRO C 1 35  ? 108.500 90.697  173.397 1.00 55.27  ? 35  PRO C CA  1 
ATOM   5703  C C   . PRO C 1 35  ? 108.618 91.814  172.388 1.00 55.27  ? 35  PRO C C   1 
ATOM   5704  O O   . PRO C 1 35  ? 108.304 92.984  172.683 1.00 55.27  ? 35  PRO C O   1 
ATOM   5705  C CB  . PRO C 1 35  ? 107.064 90.161  173.485 1.00 55.27  ? 35  PRO C CB  1 
ATOM   5706  C CG  . PRO C 1 35  ? 106.459 90.883  174.634 1.00 55.27  ? 35  PRO C CG  1 
ATOM   5707  C CD  . PRO C 1 35  ? 107.571 91.088  175.613 1.00 55.27  ? 35  PRO C CD  1 
ATOM   5708  N N   . PRO C 1 36  ? 109.068 91.509  171.171 1.00 46.86  ? 36  PRO C N   1 
ATOM   5709  C CA  . PRO C 1 36  ? 109.262 92.562  170.167 1.00 46.86  ? 36  PRO C CA  1 
ATOM   5710  C C   . PRO C 1 36  ? 107.929 93.108  169.682 1.00 46.86  ? 36  PRO C C   1 
ATOM   5711  O O   . PRO C 1 36  ? 107.034 92.349  169.305 1.00 46.86  ? 36  PRO C O   1 
ATOM   5712  C CB  . PRO C 1 36  ? 110.015 91.845  169.044 1.00 46.86  ? 36  PRO C CB  1 
ATOM   5713  C CG  . PRO C 1 36  ? 109.605 90.422  169.179 1.00 46.86  ? 36  PRO C CG  1 
ATOM   5714  C CD  . PRO C 1 36  ? 109.415 90.176  170.650 1.00 46.86  ? 36  PRO C CD  1 
ATOM   5715  N N   . VAL C 1 37  ? 107.806 94.435  169.684 1.00 43.46  ? 37  VAL C N   1 
ATOM   5716  C CA  . VAL C 1 37  ? 106.593 95.065  169.182 1.00 43.46  ? 37  VAL C CA  1 
ATOM   5717  C C   . VAL C 1 37  ? 106.486 94.827  167.682 1.00 43.46  ? 37  VAL C C   1 
ATOM   5718  O O   . VAL C 1 37  ? 107.492 94.818  166.959 1.00 43.46  ? 37  VAL C O   1 
ATOM   5719  C CB  . VAL C 1 37  ? 106.576 96.565  169.531 1.00 43.46  ? 37  VAL C CB  1 
ATOM   5720  C CG1 . VAL C 1 37  ? 107.413 97.374  168.557 1.00 43.46  ? 37  VAL C CG1 1 
ATOM   5721  C CG2 . VAL C 1 37  ? 105.150 97.079  169.561 1.00 43.46  ? 37  VAL C CG2 1 
ATOM   5722  N N   . ASN C 1 38  ? 105.267 94.588  167.210 1.00 45.20  ? 38  ASN C N   1 
ATOM   5723  C CA  . ASN C 1 38  ? 105.018 94.309  165.805 1.00 45.20  ? 38  ASN C CA  1 
ATOM   5724  C C   . ASN C 1 38  ? 104.268 95.477  165.181 1.00 45.20  ? 38  ASN C C   1 
ATOM   5725  O O   . ASN C 1 38  ? 103.387 96.069  165.810 1.00 45.20  ? 38  ASN C O   1 
ATOM   5726  C CB  . ASN C 1 38  ? 104.232 93.003  165.626 1.00 45.20  ? 38  ASN C CB  1 
ATOM   5727  C CG  . ASN C 1 38  ? 102.949 92.966  166.438 1.00 45.20  ? 38  ASN C CG  1 
ATOM   5728  O OD1 . ASN C 1 38  ? 102.050 93.774  166.216 1.00 45.20  ? 38  ASN C OD1 1 
ATOM   5729  N ND2 . ASN C 1 38  ? 102.847 92.022  167.377 1.00 45.20  ? 38  ASN C ND2 1 
ATOM   5730  N N   . VAL C 1 39  ? 104.634 95.817  163.950 1.00 47.29  ? 39  VAL C N   1 
ATOM   5731  C CA  . VAL C 1 39  ? 104.084 96.971  163.253 1.00 47.29  ? 39  VAL C CA  1 
ATOM   5732  C C   . VAL C 1 39  ? 103.425 96.494  161.970 1.00 47.29  ? 39  VAL C C   1 
ATOM   5733  O O   . VAL C 1 39  ? 104.056 95.801  161.164 1.00 47.29  ? 39  VAL C O   1 
ATOM   5734  C CB  . VAL C 1 39  ? 105.171 98.016  162.951 1.00 47.29  ? 39  VAL C CB  1 
ATOM   5735  C CG1 . VAL C 1 39  ? 104.644 99.064  161.996 1.00 47.29  ? 39  VAL C CG1 1 
ATOM   5736  C CG2 . VAL C 1 39  ? 105.654 98.655  164.233 1.00 47.29  ? 39  VAL C CG2 1 
ATOM   5737  N N   . THR C 1 40  ? 102.163 96.866  161.781 1.00 33.82  ? 40  THR C N   1 
ATOM   5738  C CA  . THR C 1 40  ? 101.408 96.537  160.577 1.00 33.82  ? 40  THR C CA  1 
ATOM   5739  C C   . THR C 1 40  ? 101.279 97.805  159.745 1.00 33.82  ? 40  THR C C   1 
ATOM   5740  O O   . THR C 1 40  ? 100.516 98.709  160.099 1.00 33.82  ? 40  THR C O   1 
ATOM   5741  C CB  . THR C 1 40  ? 100.035 95.972  160.927 1.00 33.82  ? 40  THR C CB  1 
ATOM   5742  O OG1 . THR C 1 40  ? 99.221  97.009  161.484 1.00 33.82  ? 40  THR C OG1 1 
ATOM   5743  C CG2 . THR C 1 40  ? 100.166 94.849  161.938 1.00 33.82  ? 40  THR C CG2 1 
ATOM   5744  N N   . CYS C 1 41  ? 102.017 97.870  158.641 1.00 32.83  ? 41  CYS C N   1 
ATOM   5745  C CA  . CYS C 1 41  ? 102.085 99.064  157.813 1.00 32.83  ? 41  CYS C CA  1 
ATOM   5746  C C   . CYS C 1 41  ? 101.439 98.811  156.459 1.00 32.83  ? 41  CYS C C   1 
ATOM   5747  O O   . CYS C 1 41  ? 101.659 97.767  155.842 1.00 32.83  ? 41  CYS C O   1 
ATOM   5748  C CB  . CYS C 1 41  ? 103.533 99.514  157.620 1.00 32.83  ? 41  CYS C CB  1 
ATOM   5749  S SG  . CYS C 1 41  ? 104.589 98.310  156.800 1.00 32.83  ? 41  CYS C SG  1 
ATOM   5750  N N   . ASN C 1 42  ? 100.636 99.772  156.007 1.00 30.90  ? 42  ASN C N   1 
ATOM   5751  C CA  . ASN C 1 42  ? 100.019 99.732  154.691 1.00 30.90  ? 42  ASN C CA  1 
ATOM   5752  C C   . ASN C 1 42  ? 100.255 101.061 153.991 1.00 30.90  ? 42  ASN C C   1 
ATOM   5753  O O   . ASN C 1 42  ? 100.270 102.118 154.625 1.00 30.90  ? 42  ASN C O   1 
ATOM   5754  C CB  . ASN C 1 42  ? 98.518  99.434  154.776 1.00 30.90  ? 42  ASN C CB  1 
ATOM   5755  C CG  . ASN C 1 42  ? 97.720  100.600 155.311 1.00 30.90  ? 42  ASN C CG  1 
ATOM   5756  O OD1 . ASN C 1 42  ? 98.135  101.270 156.254 1.00 30.90  ? 42  ASN C OD1 1 
ATOM   5757  N ND2 . ASN C 1 42  ? 96.564  100.850 154.710 1.00 30.90  ? 42  ASN C ND2 1 
ATOM   5758  N N   . ILE C 1 43  ? 100.440 101.000 152.676 1.00 31.09  ? 43  ILE C N   1 
ATOM   5759  C CA  . ILE C 1 43  ? 100.886 102.142 151.888 1.00 31.09  ? 43  ILE C CA  1 
ATOM   5760  C C   . ILE C 1 43  ? 99.840  102.454 150.830 1.00 31.09  ? 43  ILE C C   1 
ATOM   5761  O O   . ILE C 1 43  ? 99.442  101.570 150.064 1.00 31.09  ? 43  ILE C O   1 
ATOM   5762  C CB  . ILE C 1 43  ? 102.255 101.871 151.242 1.00 31.09  ? 43  ILE C CB  1 
ATOM   5763  C CG1 . ILE C 1 43  ? 102.477 102.780 150.039 1.00 31.09  ? 43  ILE C CG1 1 
ATOM   5764  C CG2 . ILE C 1 43  ? 102.368 100.423 150.829 1.00 31.09  ? 43  ILE C CG2 1 
ATOM   5765  C CD1 . ILE C 1 43  ? 103.734 102.455 149.269 1.00 31.09  ? 43  ILE C CD1 1 
ATOM   5766  N N   . PHE C 1 44  ? 99.401  103.707 150.786 1.00 34.50  ? 44  PHE C N   1 
ATOM   5767  C CA  . PHE C 1 44  ? 98.466  104.187 149.777 1.00 34.50  ? 44  PHE C CA  1 
ATOM   5768  C C   . PHE C 1 44  ? 99.245  104.992 148.747 1.00 34.50  ? 44  PHE C C   1 
ATOM   5769  O O   . PHE C 1 44  ? 99.930  105.955 149.101 1.00 34.50  ? 44  PHE C O   1 
ATOM   5770  C CB  . PHE C 1 44  ? 97.372  105.041 150.419 1.00 34.50  ? 44  PHE C CB  1 
ATOM   5771  C CG  . PHE C 1 44  ? 96.479  105.749 149.434 1.00 34.50  ? 44  PHE C CG  1 
ATOM   5772  C CD1 . PHE C 1 44  ? 96.842  106.969 148.891 1.00 34.50  ? 44  PHE C CD1 1 
ATOM   5773  C CD2 . PHE C 1 44  ? 95.260  105.208 149.076 1.00 34.50  ? 44  PHE C CD2 1 
ATOM   5774  C CE1 . PHE C 1 44  ? 96.018  107.619 147.996 1.00 34.50  ? 44  PHE C CE1 1 
ATOM   5775  C CE2 . PHE C 1 44  ? 94.431  105.857 148.184 1.00 34.50  ? 44  PHE C CE2 1 
ATOM   5776  C CZ  . PHE C 1 44  ? 94.812  107.064 147.644 1.00 34.50  ? 44  PHE C CZ  1 
ATOM   5777  N N   . ILE C 1 45  ? 99.131  104.611 147.482 1.00 29.82  ? 45  ILE C N   1 
ATOM   5778  C CA  . ILE C 1 45  ? 99.837  105.292 146.404 1.00 29.82  ? 45  ILE C CA  1 
ATOM   5779  C C   . ILE C 1 45  ? 98.953  106.407 145.868 1.00 29.82  ? 45  ILE C C   1 
ATOM   5780  O O   . ILE C 1 45  ? 97.778  106.185 145.556 1.00 29.82  ? 45  ILE C O   1 
ATOM   5781  C CB  . ILE C 1 45  ? 100.219 104.309 145.289 1.00 29.82  ? 45  ILE C CB  1 
ATOM   5782  C CG1 . ILE C 1 45  ? 101.306 103.357 145.775 1.00 29.82  ? 45  ILE C CG1 1 
ATOM   5783  C CG2 . ILE C 1 45  ? 100.693 105.058 144.064 1.00 29.82  ? 45  ILE C CG2 1 
ATOM   5784  C CD1 . ILE C 1 45  ? 101.845 102.466 144.694 1.00 29.82  ? 45  ILE C CD1 1 
ATOM   5785  N N   . ASN C 1 46  ? 99.514  107.609 145.764 1.00 28.63  ? 46  ASN C N   1 
ATOM   5786  C CA  . ASN C 1 46  ? 98.776  108.769 145.282 1.00 28.63  ? 46  ASN C CA  1 
ATOM   5787  C C   . ASN C 1 46  ? 99.164  109.159 143.863 1.00 28.63  ? 46  ASN C C   1 
ATOM   5788  O O   . ASN C 1 46  ? 98.297  109.283 142.995 1.00 28.63  ? 46  ASN C O   1 
ATOM   5789  C CB  . ASN C 1 46  ? 98.992  109.957 146.223 1.00 28.63  ? 46  ASN C CB  1 
ATOM   5790  C CG  . ASN C 1 46  ? 97.875  110.969 146.143 1.00 28.63  ? 46  ASN C CG  1 
ATOM   5791  O OD1 . ASN C 1 46  ? 97.330  111.226 145.072 1.00 28.63  ? 46  ASN C OD1 1 
ATOM   5792  N ND2 . ASN C 1 46  ? 97.524  111.550 147.280 1.00 28.63  ? 46  ASN C ND2 1 
ATOM   5793  N N   . SER C 1 47  ? 100.453 109.362 143.610 1.00 31.16  ? 47  SER C N   1 
ATOM   5794  C CA  . SER C 1 47  ? 100.939 109.744 142.294 1.00 31.16  ? 47  SER C CA  1 
ATOM   5795  C C   . SER C 1 47  ? 102.020 108.773 141.853 1.00 31.16  ? 47  SER C C   1 
ATOM   5796  O O   . SER C 1 47  ? 102.796 108.275 142.673 1.00 31.16  ? 47  SER C O   1 
ATOM   5797  C CB  . SER C 1 47  ? 101.488 111.173 142.292 1.00 31.16  ? 47  SER C CB  1 
ATOM   5798  O OG  . SER C 1 47  ? 102.219 111.431 141.107 1.00 31.16  ? 47  SER C OG  1 
ATOM   5799  N N   . PHE C 1 48  ? 102.065 108.512 140.551 1.00 36.57  ? 48  PHE C N   1 
ATOM   5800  C CA  . PHE C 1 48  ? 103.008 107.568 139.978 1.00 36.57  ? 48  PHE C CA  1 
ATOM   5801  C C   . PHE C 1 48  ? 103.443 108.104 138.625 1.00 36.57  ? 48  PHE C C   1 
ATOM   5802  O O   . PHE C 1 48  ? 102.681 108.800 137.949 1.00 36.57  ? 48  PHE C O   1 
ATOM   5803  C CB  . PHE C 1 48  ? 102.369 106.181 139.834 1.00 36.57  ? 48  PHE C CB  1 
ATOM   5804  C CG  . PHE C 1 48  ? 103.329 105.041 139.989 1.00 36.57  ? 48  PHE C CG  1 
ATOM   5805  C CD1 . PHE C 1 48  ? 104.347 104.841 139.077 1.00 36.57  ? 48  PHE C CD1 1 
ATOM   5806  C CD2 . PHE C 1 48  ? 103.197 104.153 141.039 1.00 36.57  ? 48  PHE C CD2 1 
ATOM   5807  C CE1 . PHE C 1 48  ? 105.223 103.787 139.218 1.00 36.57  ? 48  PHE C CE1 1 
ATOM   5808  C CE2 . PHE C 1 48  ? 104.069 103.096 141.184 1.00 36.57  ? 48  PHE C CE2 1 
ATOM   5809  C CZ  . PHE C 1 48  ? 105.083 102.914 140.273 1.00 36.57  ? 48  PHE C CZ  1 
ATOM   5810  N N   . GLY C 1 49  ? 104.668 107.792 138.237 1.00 37.22  ? 49  GLY C N   1 
ATOM   5811  C CA  . GLY C 1 49  ? 105.116 108.129 136.907 1.00 37.22  ? 49  GLY C CA  1 
ATOM   5812  C C   . GLY C 1 49  ? 106.561 108.565 136.913 1.00 37.22  ? 49  GLY C C   1 
ATOM   5813  O O   . GLY C 1 49  ? 107.285 108.352 137.883 1.00 37.22  ? 49  GLY C O   1 
ATOM   5814  N N   . SER C 1 50  ? 106.959 109.186 135.803 1.00 45.92  ? 50  SER C N   1 
ATOM   5815  C CA  . SER C 1 50  ? 108.332 109.640 135.591 1.00 45.92  ? 50  SER C CA  1 
ATOM   5816  C C   . SER C 1 50  ? 109.318 108.481 135.728 1.00 45.92  ? 50  SER C C   1 
ATOM   5817  O O   . SER C 1 50  ? 110.316 108.563 136.445 1.00 45.92  ? 50  SER C O   1 
ATOM   5818  C CB  . SER C 1 50  ? 108.686 110.784 136.543 1.00 45.92  ? 50  SER C CB  1 
ATOM   5819  O OG  . SER C 1 50  ? 110.028 111.200 136.362 1.00 45.92  ? 50  SER C OG  1 
ATOM   5820  N N   . ILE C 1 51  ? 109.025 107.388 135.026 1.00 45.14  ? 51  ILE C N   1 
ATOM   5821  C CA  . ILE C 1 51  ? 109.879 106.199 135.040 1.00 45.14  ? 51  ILE C CA  1 
ATOM   5822  C C   . ILE C 1 51  ? 110.913 106.399 133.938 1.00 45.14  ? 51  ILE C C   1 
ATOM   5823  O O   . ILE C 1 51  ? 110.754 105.936 132.809 1.00 45.14  ? 51  ILE C O   1 
ATOM   5824  C CB  . ILE C 1 51  ? 109.076 104.916 134.858 1.00 45.14  ? 51  ILE C CB  1 
ATOM   5825  C CG1 . ILE C 1 51  ? 107.898 104.888 135.830 1.00 45.14  ? 51  ILE C CG1 1 
ATOM   5826  C CG2 . ILE C 1 51  ? 109.964 103.701 135.054 1.00 45.14  ? 51  ILE C CG2 1 
ATOM   5827  C CD1 . ILE C 1 51  ? 107.092 103.618 135.771 1.00 45.14  ? 51  ILE C CD1 1 
ATOM   5828  N N   . ALA C 1 52  ? 111.993 107.097 134.273 1.00 59.46  ? 52  ALA C N   1 
ATOM   5829  C CA  . ALA C 1 52  ? 113.042 107.389 133.306 1.00 59.46  ? 52  ALA C CA  1 
ATOM   5830  C C   . ALA C 1 52  ? 113.972 106.190 133.183 1.00 59.46  ? 52  ALA C C   1 
ATOM   5831  O O   . ALA C 1 52  ? 114.660 105.829 134.144 1.00 59.46  ? 52  ALA C O   1 
ATOM   5832  C CB  . ALA C 1 52  ? 113.819 108.636 133.721 1.00 59.46  ? 52  ALA C CB  1 
ATOM   5833  N N   . GLU C 1 53  ? 113.996 105.574 132.000 1.00 64.31  ? 53  GLU C N   1 
ATOM   5834  C CA  . GLU C 1 53  ? 114.859 104.422 131.777 1.00 64.31  ? 53  GLU C CA  1 
ATOM   5835  C C   . GLU C 1 53  ? 116.333 104.802 131.733 1.00 64.31  ? 53  GLU C C   1 
ATOM   5836  O O   . GLU C 1 53  ? 117.188 103.934 131.938 1.00 64.31  ? 53  GLU C O   1 
ATOM   5837  C CB  . GLU C 1 53  ? 114.468 103.714 130.479 1.00 64.31  ? 53  GLU C CB  1 
ATOM   5838  C CG  . GLU C 1 53  ? 114.506 104.600 129.248 1.00 64.31  ? 53  GLU C CG  1 
ATOM   5839  C CD  . GLU C 1 53  ? 113.197 105.325 129.011 1.00 64.31  ? 53  GLU C CD  1 
ATOM   5840  O OE1 . GLU C 1 53  ? 112.237 105.081 129.771 1.00 64.31  ? 53  GLU C OE1 1 
ATOM   5841  O OE2 . GLU C 1 53  ? 113.129 106.140 128.068 1.00 64.31  ? 53  GLU C OE2 1 
ATOM   5842  N N   . THR C 1 54  ? 116.648 106.072 131.472 1.00 64.46  ? 54  THR C N   1 
ATOM   5843  C CA  . THR C 1 54  ? 118.045 106.482 131.374 1.00 64.46  ? 54  THR C CA  1 
ATOM   5844  C C   . THR C 1 54  ? 118.770 106.362 132.708 1.00 64.46  ? 54  THR C C   1 
ATOM   5845  O O   . THR C 1 54  ? 119.945 105.981 132.739 1.00 64.46  ? 54  THR C O   1 
ATOM   5846  C CB  . THR C 1 54  ? 118.139 107.915 130.852 1.00 64.46  ? 54  THR C CB  1 
ATOM   5847  O OG1 . THR C 1 54  ? 119.454 108.428 131.097 1.00 64.46  ? 54  THR C OG1 1 
ATOM   5848  C CG2 . THR C 1 54  ? 117.110 108.804 131.535 1.00 64.46  ? 54  THR C CG2 1 
ATOM   5849  N N   . THR C 1 55  ? 118.099 106.684 133.811 1.00 62.25  ? 55  THR C N   1 
ATOM   5850  C CA  . THR C 1 55  ? 118.695 106.611 135.136 1.00 62.25  ? 55  THR C CA  1 
ATOM   5851  C C   . THR C 1 55  ? 118.129 105.481 135.983 1.00 62.25  ? 55  THR C C   1 
ATOM   5852  O O   . THR C 1 55  ? 118.508 105.355 137.152 1.00 62.25  ? 55  THR C O   1 
ATOM   5853  C CB  . THR C 1 55  ? 118.520 107.948 135.866 1.00 62.25  ? 55  THR C CB  1 
ATOM   5854  O OG1 . THR C 1 55  ? 118.962 107.817 137.223 1.00 62.25  ? 55  THR C OG1 1 
ATOM   5855  C CG2 . THR C 1 55  ? 117.067 108.390 135.835 1.00 62.25  ? 55  THR C CG2 1 
ATOM   5856  N N   . MET C 1 56  ? 117.242 104.659 135.424 1.00 59.16  ? 56  MET C N   1 
ATOM   5857  C CA  . MET C 1 56  ? 116.726 103.453 136.073 1.00 59.16  ? 56  MET C CA  1 
ATOM   5858  C C   . MET C 1 56  ? 116.113 103.762 137.440 1.00 59.16  ? 56  MET C C   1 
ATOM   5859  O O   . MET C 1 56  ? 116.557 103.268 138.476 1.00 59.16  ? 56  MET C O   1 
ATOM   5860  C CB  . MET C 1 56  ? 117.823 102.389 136.199 1.00 59.16  ? 56  MET C CB  1 
ATOM   5861  C CG  . MET C 1 56  ? 118.841 102.377 135.068 1.00 59.16  ? 56  MET C CG  1 
ATOM   5862  S SD  . MET C 1 56  ? 118.309 101.414 133.640 1.00 59.16  ? 56  MET C SD  1 
ATOM   5863  C CE  . MET C 1 56  ? 118.702 99.755  134.185 1.00 59.16  ? 56  MET C CE  1 
ATOM   5864  N N   . ASP C 1 57  ? 115.070 104.589 137.428 1.00 48.41  ? 57  ASP C N   1 
ATOM   5865  C CA  . ASP C 1 57  ? 114.362 104.904 138.661 1.00 48.41  ? 57  ASP C CA  1 
ATOM   5866  C C   . ASP C 1 57  ? 112.968 105.420 138.339 1.00 48.41  ? 57  ASP C C   1 
ATOM   5867  O O   . ASP C 1 57  ? 112.677 105.820 137.211 1.00 48.41  ? 57  ASP C O   1 
ATOM   5868  C CB  . ASP C 1 57  ? 115.140 105.913 139.518 1.00 48.41  ? 57  ASP C CB  1 
ATOM   5869  C CG  . ASP C 1 57  ? 115.326 107.262 138.838 1.00 48.41  ? 57  ASP C CG  1 
ATOM   5870  O OD1 . ASP C 1 57  ? 114.344 107.857 138.349 1.00 48.41  ? 57  ASP C OD1 1 
ATOM   5871  O OD2 . ASP C 1 57  ? 116.477 107.745 138.820 1.00 48.41  ? 57  ASP C OD2 1 
ATOM   5872  N N   . TYR C 1 58  ? 112.113 105.407 139.358 1.00 35.76  ? 58  TYR C N   1 
ATOM   5873  C CA  . TYR C 1 58  ? 110.759 105.926 139.256 1.00 35.76  ? 58  TYR C CA  1 
ATOM   5874  C C   . TYR C 1 58  ? 110.401 106.608 140.566 1.00 35.76  ? 58  TYR C C   1 
ATOM   5875  O O   . TYR C 1 58  ? 110.963 106.299 141.618 1.00 35.76  ? 58  TYR C O   1 
ATOM   5876  C CB  . TYR C 1 58  ? 109.754 104.817 138.941 1.00 35.76  ? 58  TYR C CB  1 
ATOM   5877  C CG  . TYR C 1 58  ? 109.534 103.851 140.078 1.00 35.76  ? 58  TYR C CG  1 
ATOM   5878  C CD1 . TYR C 1 58  ? 110.476 102.885 140.382 1.00 35.76  ? 58  TYR C CD1 1 
ATOM   5879  C CD2 . TYR C 1 58  ? 108.378 103.898 140.839 1.00 35.76  ? 58  TYR C CD2 1 
ATOM   5880  C CE1 . TYR C 1 58  ? 110.277 101.998 141.416 1.00 35.76  ? 58  TYR C CE1 1 
ATOM   5881  C CE2 . TYR C 1 58  ? 108.171 103.014 141.875 1.00 35.76  ? 58  TYR C CE2 1 
ATOM   5882  C CZ  . TYR C 1 58  ? 109.124 102.067 142.159 1.00 35.76  ? 58  TYR C CZ  1 
ATOM   5883  O OH  . TYR C 1 58  ? 108.923 101.184 143.191 1.00 35.76  ? 58  TYR C OH  1 
ATOM   5884  N N   . ARG C 1 59  ? 109.457 107.542 140.498 1.00 33.84  ? 59  ARG C N   1 
ATOM   5885  C CA  . ARG C 1 59  ? 109.068 108.329 141.659 1.00 33.84  ? 59  ARG C CA  1 
ATOM   5886  C C   . ARG C 1 59  ? 107.611 108.067 142.011 1.00 33.84  ? 59  ARG C C   1 
ATOM   5887  O O   . ARG C 1 59  ? 106.779 107.841 141.128 1.00 33.84  ? 59  ARG C O   1 
ATOM   5888  C CB  . ARG C 1 59  ? 109.296 109.825 141.421 1.00 33.84  ? 59  ARG C CB  1 
ATOM   5889  C CG  . ARG C 1 59  ? 108.266 110.497 140.539 1.00 33.84  ? 59  ARG C CG  1 
ATOM   5890  C CD  . ARG C 1 59  ? 108.762 111.846 140.058 1.00 33.84  ? 59  ARG C CD  1 
ATOM   5891  N NE  . ARG C 1 59  ? 109.548 112.534 141.074 1.00 33.84  ? 59  ARG C NE  1 
ATOM   5892  C CZ  . ARG C 1 59  ? 109.031 113.243 142.068 1.00 33.84  ? 59  ARG C CZ  1 
ATOM   5893  N NH1 . ARG C 1 59  ? 107.723 113.369 142.219 1.00 33.84  ? 59  ARG C NH1 1 
ATOM   5894  N NH2 . ARG C 1 59  ? 109.847 113.840 142.931 1.00 33.84  ? 59  ARG C NH2 1 
ATOM   5895  N N   . VAL C 1 60  ? 107.311 108.083 143.311 1.00 30.50  ? 60  VAL C N   1 
ATOM   5896  C CA  . VAL C 1 60  ? 105.968 107.831 143.815 1.00 30.50  ? 60  VAL C CA  1 
ATOM   5897  C C   . VAL C 1 60  ? 105.644 108.833 144.913 1.00 30.50  ? 60  VAL C C   1 
ATOM   5898  O O   . VAL C 1 60  ? 106.529 109.465 145.492 1.00 30.50  ? 60  VAL C O   1 
ATOM   5899  C CB  . VAL C 1 60  ? 105.806 106.396 144.358 1.00 30.50  ? 60  VAL C CB  1 
ATOM   5900  C CG1 . VAL C 1 60  ? 105.873 105.394 143.231 1.00 30.50  ? 60  VAL C CG1 1 
ATOM   5901  C CG2 . VAL C 1 60  ? 106.873 106.106 145.387 1.00 30.50  ? 60  VAL C CG2 1 
ATOM   5902  N N   . ASN C 1 61  ? 104.351 108.973 145.191 1.00 35.70  ? 61  ASN C N   1 
ATOM   5903  C CA  . ASN C 1 61  ? 103.850 109.754 146.318 1.00 35.70  ? 61  ASN C CA  1 
ATOM   5904  C C   . ASN C 1 61  ? 102.961 108.836 147.143 1.00 35.70  ? 61  ASN C C   1 
ATOM   5905  O O   . ASN C 1 61  ? 101.859 108.486 146.711 1.00 35.70  ? 61  ASN C O   1 
ATOM   5906  C CB  . ASN C 1 61  ? 103.075 110.980 145.845 1.00 35.70  ? 61  ASN C CB  1 
ATOM   5907  C CG  . ASN C 1 61  ? 103.956 112.192 145.674 1.00 35.70  ? 61  ASN C CG  1 
ATOM   5908  O OD1 . ASN C 1 61  ? 105.171 112.074 145.535 1.00 35.70  ? 61  ASN C OD1 1 
ATOM   5909  N ND2 . ASN C 1 61  ? 103.347 113.371 145.685 1.00 35.70  ? 61  ASN C ND2 1 
ATOM   5910  N N   . ILE C 1 62  ? 103.429 108.449 148.324 1.00 47.29  ? 62  ILE C N   1 
ATOM   5911  C CA  . ILE C 1 62  ? 102.765 107.427 149.119 1.00 47.29  ? 62  ILE C CA  1 
ATOM   5912  C C   . ILE C 1 62  ? 102.239 108.047 150.403 1.00 47.29  ? 62  ILE C C   1 
ATOM   5913  O O   . ILE C 1 62  ? 102.852 108.959 150.966 1.00 47.29  ? 62  ILE C O   1 
ATOM   5914  C CB  . ILE C 1 62  ? 103.709 106.245 149.420 1.00 47.29  ? 62  ILE C CB  1 
ATOM   5915  C CG1 . ILE C 1 62  ? 104.691 106.593 150.532 1.00 47.29  ? 62  ILE C CG1 1 
ATOM   5916  C CG2 . ILE C 1 62  ? 104.474 105.858 148.173 1.00 47.29  ? 62  ILE C CG2 1 
ATOM   5917  C CD1 . ILE C 1 62  ? 105.658 105.482 150.846 1.00 47.29  ? 62  ILE C CD1 1 
ATOM   5918  N N   . PHE C 1 63  ? 101.073 107.577 150.838 1.00 47.29  ? 63  PHE C N   1 
ATOM   5919  C CA  . PHE C 1 63  ? 100.522 107.938 152.140 1.00 47.29  ? 63  PHE C CA  1 
ATOM   5920  C C   . PHE C 1 63  ? 100.829 106.824 153.137 1.00 47.29  ? 63  PHE C C   1 
ATOM   5921  O O   . PHE C 1 63  ? 99.951  106.096 153.598 1.00 47.29  ? 63  PHE C O   1 
ATOM   5922  C CB  . PHE C 1 63  ? 99.022  108.191 152.034 1.00 47.29  ? 63  PHE C CB  1 
ATOM   5923  C CG  . PHE C 1 63  ? 98.668  109.524 151.455 1.00 47.29  ? 63  PHE C CG  1 
ATOM   5924  C CD1 . PHE C 1 63  ? 99.644  110.356 150.946 1.00 47.29  ? 63  PHE C CD1 1 
ATOM   5925  C CD2 . PHE C 1 63  ? 97.354  109.945 151.419 1.00 47.29  ? 63  PHE C CD2 1 
ATOM   5926  C CE1 . PHE C 1 63  ? 99.313  111.580 150.414 1.00 47.29  ? 63  PHE C CE1 1 
ATOM   5927  C CE2 . PHE C 1 63  ? 97.019  111.166 150.888 1.00 47.29  ? 63  PHE C CE2 1 
ATOM   5928  C CZ  . PHE C 1 63  ? 97.999  111.985 150.386 1.00 47.29  ? 63  PHE C CZ  1 
ATOM   5929  N N   . LEU C 1 64  ? 102.114 106.697 153.455 1.00 37.71  ? 64  LEU C N   1 
ATOM   5930  C CA  . LEU C 1 64  ? 102.570 105.623 154.325 1.00 37.71  ? 64  LEU C CA  1 
ATOM   5931  C C   . LEU C 1 64  ? 101.861 105.678 155.670 1.00 37.71  ? 64  LEU C C   1 
ATOM   5932  O O   . LEU C 1 64  ? 101.719 106.749 156.266 1.00 37.71  ? 64  LEU C O   1 
ATOM   5933  C CB  . LEU C 1 64  ? 104.078 105.719 154.520 1.00 37.71  ? 64  LEU C CB  1 
ATOM   5934  C CG  . LEU C 1 64  ? 104.643 104.838 155.625 1.00 37.71  ? 64  LEU C CG  1 
ATOM   5935  C CD1 . LEU C 1 64  ? 104.489 103.381 155.255 1.00 37.71  ? 64  LEU C CD1 1 
ATOM   5936  C CD2 . LEU C 1 64  ? 106.091 105.184 155.860 1.00 37.71  ? 64  LEU C CD2 1 
ATOM   5937  N N   . ARG C 1 65  ? 101.407 104.520 156.143 1.00 31.64  ? 65  ARG C N   1 
ATOM   5938  C CA  . ARG C 1 65  ? 100.667 104.413 157.392 1.00 31.64  ? 65  ARG C CA  1 
ATOM   5939  C C   . ARG C 1 65  ? 101.226 103.267 158.217 1.00 31.64  ? 65  ARG C C   1 
ATOM   5940  O O   . ARG C 1 65  ? 101.571 102.215 157.673 1.00 31.64  ? 65  ARG C O   1 
ATOM   5941  C CB  . ARG C 1 65  ? 99.180  104.189 157.129 1.00 31.64  ? 65  ARG C CB  1 
ATOM   5942  C CG  . ARG C 1 65  ? 98.524  105.324 156.378 1.00 31.64  ? 65  ARG C CG  1 
ATOM   5943  C CD  . ARG C 1 65  ? 97.018  105.247 156.463 1.00 31.64  ? 65  ARG C CD  1 
ATOM   5944  N NE  . ARG C 1 65  ? 96.439  104.611 155.288 1.00 31.64  ? 65  ARG C NE  1 
ATOM   5945  C CZ  . ARG C 1 65  ? 96.104  105.256 154.181 1.00 31.64  ? 65  ARG C CZ  1 
ATOM   5946  N NH1 . ARG C 1 65  ? 96.298  106.557 154.055 1.00 31.64  ? 65  ARG C NH1 1 
ATOM   5947  N NH2 . ARG C 1 65  ? 95.563  104.578 153.174 1.00 31.64  ? 65  ARG C NH2 1 
ATOM   5948  N N   . GLN C 1 66  ? 101.315 103.469 159.529 1.00 29.75  ? 66  GLN C N   1 
ATOM   5949  C CA  . GLN C 1 66  ? 101.858 102.472 160.437 1.00 29.75  ? 66  GLN C CA  1 
ATOM   5950  C C   . GLN C 1 66  ? 100.966 102.346 161.661 1.00 29.75  ? 66  GLN C C   1 
ATOM   5951  O O   . GLN C 1 66  ? 100.264 103.288 162.036 1.00 29.75  ? 66  GLN C O   1 
ATOM   5952  C CB  . GLN C 1 66  ? 103.281 102.826 160.882 1.00 29.75  ? 66  GLN C CB  1 
ATOM   5953  C CG  . GLN C 1 66  ? 104.166 103.366 159.780 1.00 29.75  ? 66  GLN C CG  1 
ATOM   5954  C CD  . GLN C 1 66  ? 105.586 103.593 160.240 1.00 29.75  ? 66  GLN C CD  1 
ATOM   5955  O OE1 . GLN C 1 66  ? 106.092 102.875 161.099 1.00 29.75  ? 66  GLN C OE1 1 
ATOM   5956  N NE2 . GLN C 1 66  ? 106.237 104.599 159.674 1.00 29.75  ? 66  GLN C NE2 1 
ATOM   5957  N N   . LYS C 1 67  ? 100.993 101.168 162.281 1.00 32.98  ? 67  LYS C N   1 
ATOM   5958  C CA  . LYS C 1 67  ? 100.271 100.925 163.520 1.00 32.98  ? 67  LYS C CA  1 
ATOM   5959  C C   . LYS C 1 67  ? 101.134 100.089 164.451 1.00 32.98  ? 67  LYS C C   1 
ATOM   5960  O O   . LYS C 1 67  ? 101.967 99.300  164.003 1.00 32.98  ? 67  LYS C O   1 
ATOM   5961  C CB  . LYS C 1 67  ? 98.936  100.206 163.285 1.00 32.98  ? 67  LYS C CB  1 
ATOM   5962  C CG  . LYS C 1 67  ? 98.038  100.851 162.248 1.00 32.98  ? 67  LYS C CG  1 
ATOM   5963  C CD  . LYS C 1 67  ? 96.744  100.075 162.085 1.00 32.98  ? 67  LYS C CD  1 
ATOM   5964  C CE  . LYS C 1 67  ? 96.009  100.491 160.824 1.00 32.98  ? 67  LYS C CE  1 
ATOM   5965  N NZ  . LYS C 1 67  ? 94.680  99.832  160.716 1.00 32.98  ? 67  LYS C NZ  1 
ATOM   5966  N N   . TRP C 1 68  ? 100.928 100.272 165.753 1.00 35.71  ? 68  TRP C N   1 
ATOM   5967  C CA  . TRP C 1 68  ? 101.577 99.440  166.757 1.00 35.71  ? 68  TRP C CA  1 
ATOM   5968  C C   . TRP C 1 68  ? 100.826 99.598  168.068 1.00 35.71  ? 68  TRP C C   1 
ATOM   5969  O O   . TRP C 1 68  ? 100.094 100.569 168.269 1.00 35.71  ? 68  TRP C O   1 
ATOM   5970  C CB  . TRP C 1 68  ? 103.054 99.800  166.930 1.00 35.71  ? 68  TRP C CB  1 
ATOM   5971  C CG  . TRP C 1 68  ? 103.285 101.183 167.426 1.00 35.71  ? 68  TRP C CG  1 
ATOM   5972  C CD1 . TRP C 1 68  ? 103.440 101.571 168.720 1.00 35.71  ? 68  TRP C CD1 1 
ATOM   5973  C CD2 . TRP C 1 68  ? 103.389 102.369 166.635 1.00 35.71  ? 68  TRP C CD2 1 
ATOM   5974  N NE1 . TRP C 1 68  ? 103.636 102.927 168.787 1.00 35.71  ? 68  TRP C NE1 1 
ATOM   5975  C CE2 . TRP C 1 68  ? 103.608 103.440 167.518 1.00 35.71  ? 68  TRP C CE2 1 
ATOM   5976  C CE3 . TRP C 1 68  ? 103.319 102.629 165.265 1.00 35.71  ? 68  TRP C CE3 1 
ATOM   5977  C CZ2 . TRP C 1 68  ? 103.756 104.750 167.078 1.00 35.71  ? 68  TRP C CZ2 1 
ATOM   5978  C CZ3 . TRP C 1 68  ? 103.466 103.930 164.831 1.00 35.71  ? 68  TRP C CZ3 1 
ATOM   5979  C CH2 . TRP C 1 68  ? 103.680 104.974 165.733 1.00 35.71  ? 68  TRP C CH2 1 
ATOM   5980  N N   . ASN C 1 69  ? 101.021 98.634  168.961 1.00 41.47  ? 69  ASN C N   1 
ATOM   5981  C CA  . ASN C 1 69  ? 100.323 98.602  170.242 1.00 41.47  ? 69  ASN C CA  1 
ATOM   5982  C C   . ASN C 1 69  ? 101.254 99.133  171.325 1.00 41.47  ? 69  ASN C C   1 
ATOM   5983  O O   . ASN C 1 69  ? 102.211 98.458  171.715 1.00 41.47  ? 69  ASN C O   1 
ATOM   5984  C CB  . ASN C 1 69  ? 99.852  97.189  170.571 1.00 41.47  ? 69  ASN C CB  1 
ATOM   5985  C CG  . ASN C 1 69  ? 98.838  97.163  171.694 1.00 41.47  ? 69  ASN C CG  1 
ATOM   5986  O OD1 . ASN C 1 69  ? 98.209  98.175  171.998 1.00 41.47  ? 69  ASN C OD1 1 
ATOM   5987  N ND2 . ASN C 1 69  ? 98.673  96.003  172.317 1.00 41.47  ? 69  ASN C ND2 1 
ATOM   5988  N N   . ASP C 1 70  ? 100.965 100.336 171.813 1.00 48.17  ? 70  ASP C N   1 
ATOM   5989  C CA  . ASP C 1 70  ? 101.763 100.958 172.863 1.00 48.17  ? 70  ASP C CA  1 
ATOM   5990  C C   . ASP C 1 70  ? 100.983 100.937 174.168 1.00 48.17  ? 70  ASP C C   1 
ATOM   5991  O O   . ASP C 1 70  ? 99.996  101.676 174.304 1.00 48.17  ? 70  ASP C O   1 
ATOM   5992  C CB  . ASP C 1 70  ? 102.128 102.392 172.481 1.00 48.17  ? 70  ASP C CB  1 
ATOM   5993  C CG  . ASP C 1 70  ? 103.373 102.881 173.187 1.00 48.17  ? 70  ASP C CG  1 
ATOM   5994  O OD1 . ASP C 1 70  ? 103.634 102.422 174.318 1.00 48.17  ? 70  ASP C OD1 1 
ATOM   5995  O OD2 . ASP C 1 70  ? 104.092 103.723 172.611 1.00 48.17  ? 70  ASP C OD2 1 
ATOM   5996  N N   . PRO C 1 71  ? 101.373 100.118 175.148 1.00 47.94  ? 71  PRO C N   1 
ATOM   5997  C CA  . PRO C 1 71  ? 100.583 100.025 176.384 1.00 47.94  ? 71  PRO C CA  1 
ATOM   5998  C C   . PRO C 1 71  ? 100.629 101.273 177.247 1.00 47.94  ? 71  PRO C C   1 
ATOM   5999  O O   . PRO C 1 71  ? 99.771  101.424 178.125 1.00 47.94  ? 71  PRO C O   1 
ATOM   6000  C CB  . PRO C 1 71  ? 101.208 98.827  177.110 1.00 47.94  ? 71  PRO C CB  1 
ATOM   6001  C CG  . PRO C 1 71  ? 102.600 98.766  176.592 1.00 47.94  ? 71  PRO C CG  1 
ATOM   6002  C CD  . PRO C 1 71  ? 102.532 99.211  175.160 1.00 47.94  ? 71  PRO C CD  1 
ATOM   6003  N N   . ARG C 1 72  ? 101.591 102.169 177.036 1.00 46.30  ? 72  ARG C N   1 
ATOM   6004  C CA  . ARG C 1 72  ? 101.731 103.343 177.888 1.00 46.30  ? 72  ARG C CA  1 
ATOM   6005  C C   . ARG C 1 72  ? 100.836 104.501 177.470 1.00 46.30  ? 72  ARG C C   1 
ATOM   6006  O O   . ARG C 1 72  ? 100.837 105.535 178.145 1.00 46.30  ? 72  ARG C O   1 
ATOM   6007  C CB  . ARG C 1 72  ? 103.188 103.807 177.909 1.00 46.30  ? 72  ARG C CB  1 
ATOM   6008  C CG  . ARG C 1 72  ? 104.158 102.773 178.447 1.00 46.30  ? 72  ARG C CG  1 
ATOM   6009  C CD  . ARG C 1 72  ? 105.594 103.177 178.176 1.00 46.30  ? 72  ARG C CD  1 
ATOM   6010  N NE  . ARG C 1 72  ? 105.820 103.444 176.761 1.00 46.30  ? 72  ARG C NE  1 
ATOM   6011  C CZ  . ARG C 1 72  ? 106.984 103.818 176.248 1.00 46.30  ? 72  ARG C CZ  1 
ATOM   6012  N NH1 . ARG C 1 72  ? 108.053 103.982 177.008 1.00 46.30  ? 72  ARG C NH1 1 
ATOM   6013  N NH2 . ARG C 1 72  ? 107.074 104.036 174.940 1.00 46.30  ? 72  ARG C NH2 1 
ATOM   6014  N N   . LEU C 1 73  ? 100.080 104.361 176.383 1.00 45.92  ? 73  LEU C N   1 
ATOM   6015  C CA  . LEU C 1 73  ? 99.202  105.417 175.898 1.00 45.92  ? 73  LEU C CA  1 
ATOM   6016  C C   . LEU C 1 73  ? 97.732  105.130 176.171 1.00 45.92  ? 73  LEU C C   1 
ATOM   6017  O O   . LEU C 1 73  ? 96.865  105.821 175.629 1.00 45.92  ? 73  LEU C O   1 
ATOM   6018  C CB  . LEU C 1 73  ? 99.420  105.637 174.401 1.00 45.92  ? 73  LEU C CB  1 
ATOM   6019  C CG  . LEU C 1 73  ? 100.314 106.810 174.004 1.00 45.92  ? 73  LEU C CG  1 
ATOM   6020  C CD1 . LEU C 1 73  ? 101.619 106.774 174.769 1.00 45.92  ? 73  LEU C CD1 1 
ATOM   6021  C CD2 . LEU C 1 73  ? 100.571 106.784 172.513 1.00 45.92  ? 73  LEU C CD2 1 
ATOM   6022  N N   . ALA C 1 74  ? 97.430  104.126 176.990 1.00 55.95  ? 74  ALA C N   1 
ATOM   6023  C CA  . ALA C 1 74  ? 96.045  103.799 177.290 1.00 55.95  ? 74  ALA C CA  1 
ATOM   6024  C C   . ALA C 1 74  ? 95.400  104.905 178.112 1.00 55.95  ? 74  ALA C C   1 
ATOM   6025  O O   . ALA C 1 74  ? 96.015  105.464 179.024 1.00 55.95  ? 74  ALA C O   1 
ATOM   6026  C CB  . ALA C 1 74  ? 95.961  102.472 178.041 1.00 55.95  ? 74  ALA C CB  1 
ATOM   6027  N N   . TYR C 1 75  ? 94.150  105.220 177.783 1.00 68.03  ? 75  TYR C N   1 
ATOM   6028  C CA  . TYR C 1 75  ? 93.398  106.249 178.484 1.00 68.03  ? 75  TYR C CA  1 
ATOM   6029  C C   . TYR C 1 75  ? 91.954  105.796 178.638 1.00 68.03  ? 75  TYR C C   1 
ATOM   6030  O O   . TYR C 1 75  ? 91.460  104.971 177.866 1.00 68.03  ? 75  TYR C O   1 
ATOM   6031  C CB  . TYR C 1 75  ? 93.481  107.598 177.748 1.00 68.03  ? 75  TYR C CB  1 
ATOM   6032  C CG  . TYR C 1 75  ? 92.667  107.684 176.474 1.00 68.03  ? 75  TYR C CG  1 
ATOM   6033  C CD1 . TYR C 1 75  ? 91.301  107.933 176.506 1.00 68.03  ? 75  TYR C CD1 1 
ATOM   6034  C CD2 . TYR C 1 75  ? 93.268  107.512 175.238 1.00 68.03  ? 75  TYR C CD2 1 
ATOM   6035  C CE1 . TYR C 1 75  ? 90.563  108.008 175.347 1.00 68.03  ? 75  TYR C CE1 1 
ATOM   6036  C CE2 . TYR C 1 75  ? 92.537  107.586 174.073 1.00 68.03  ? 75  TYR C CE2 1 
ATOM   6037  C CZ  . TYR C 1 75  ? 91.185  107.835 174.134 1.00 68.03  ? 75  TYR C CZ  1 
ATOM   6038  O OH  . TYR C 1 75  ? 90.449  107.909 172.976 1.00 68.03  ? 75  TYR C OH  1 
ATOM   6039  N N   . SER C 1 76  ? 91.283  106.344 179.650 1.00 80.13  ? 76  SER C N   1 
ATOM   6040  C CA  . SER C 1 76  ? 89.878  106.032 179.882 1.00 80.13  ? 76  SER C CA  1 
ATOM   6041  C C   . SER C 1 76  ? 89.018  107.243 180.204 1.00 80.13  ? 76  SER C C   1 
ATOM   6042  O O   . SER C 1 76  ? 87.793  107.101 180.249 1.00 80.13  ? 76  SER C O   1 
ATOM   6043  C CB  . SER C 1 76  ? 89.741  105.010 181.018 1.00 80.13  ? 76  SER C CB  1 
ATOM   6044  O OG  . SER C 1 76  ? 90.542  103.868 180.772 1.00 80.13  ? 76  SER C OG  1 
ATOM   6045  N N   . GLU C 1 77  ? 89.603  108.420 180.435 1.00 85.56  ? 77  GLU C N   1 
ATOM   6046  C CA  . GLU C 1 77  ? 88.810  109.589 180.800 1.00 85.56  ? 77  GLU C CA  1 
ATOM   6047  C C   . GLU C 1 77  ? 87.888  110.018 179.665 1.00 85.56  ? 77  GLU C C   1 
ATOM   6048  O O   . GLU C 1 77  ? 86.732  110.385 179.904 1.00 85.56  ? 77  GLU C O   1 
ATOM   6049  C CB  . GLU C 1 77  ? 89.732  110.737 181.211 1.00 85.56  ? 77  GLU C CB  1 
ATOM   6050  C CG  . GLU C 1 77  ? 90.969  110.891 180.339 1.00 85.56  ? 77  GLU C CG  1 
ATOM   6051  C CD  . GLU C 1 77  ? 92.152  110.093 180.852 1.00 85.56  ? 77  GLU C CD  1 
ATOM   6052  O OE1 . GLU C 1 77  ? 91.933  109.058 181.517 1.00 85.56  ? 77  GLU C OE1 1 
ATOM   6053  O OE2 . GLU C 1 77  ? 93.303  110.500 180.591 1.00 85.56  ? 77  GLU C OE2 1 
ATOM   6054  N N   . TYR C 1 78  ? 88.377  109.982 178.429 1.00 81.81  ? 78  TYR C N   1 
ATOM   6055  C CA  . TYR C 1 78  ? 87.581  110.408 177.287 1.00 81.81  ? 78  TYR C CA  1 
ATOM   6056  C C   . TYR C 1 78  ? 86.756  109.238 176.770 1.00 81.81  ? 78  TYR C C   1 
ATOM   6057  O O   . TYR C 1 78  ? 87.332  108.209 176.393 1.00 81.81  ? 78  TYR C O   1 
ATOM   6058  C CB  . TYR C 1 78  ? 88.472  110.945 176.183 1.00 81.81  ? 78  TYR C CB  1 
ATOM   6059  C CG  . TYR C 1 78  ? 88.787  112.415 176.329 1.00 81.81  ? 78  TYR C CG  1 
ATOM   6060  C CD1 . TYR C 1 78  ? 87.797  113.374 176.178 1.00 81.81  ? 78  TYR C CD1 1 
ATOM   6061  C CD2 . TYR C 1 78  ? 90.074  112.843 176.621 1.00 81.81  ? 78  TYR C CD2 1 
ATOM   6062  C CE1 . TYR C 1 78  ? 88.078  114.718 176.312 1.00 81.81  ? 78  TYR C CE1 1 
ATOM   6063  C CE2 . TYR C 1 78  ? 90.365  114.186 176.755 1.00 81.81  ? 78  TYR C CE2 1 
ATOM   6064  C CZ  . TYR C 1 78  ? 89.363  115.119 176.600 1.00 81.81  ? 78  TYR C CZ  1 
ATOM   6065  O OH  . TYR C 1 78  ? 89.647  116.458 176.733 1.00 81.81  ? 78  TYR C OH  1 
ATOM   6066  N N   . PRO C 1 79  ? 85.425  109.341 176.742 1.00 84.95  ? 79  PRO C N   1 
ATOM   6067  C CA  . PRO C 1 79  ? 84.615  108.220 176.237 1.00 84.95  ? 79  PRO C CA  1 
ATOM   6068  C C   . PRO C 1 79  ? 84.863  107.900 174.773 1.00 84.95  ? 79  PRO C C   1 
ATOM   6069  O O   . PRO C 1 79  ? 84.674  106.749 174.361 1.00 84.95  ? 79  PRO C O   1 
ATOM   6070  C CB  . PRO C 1 79  ? 83.175  108.696 176.476 1.00 84.95  ? 79  PRO C CB  1 
ATOM   6071  C CG  . PRO C 1 79  ? 83.271  110.186 176.507 1.00 84.95  ? 79  PRO C CG  1 
ATOM   6072  C CD  . PRO C 1 79  ? 84.599  110.497 177.128 1.00 84.95  ? 79  PRO C CD  1 
ATOM   6073  N N   . ASP C 1 80  ? 85.271  108.883 173.975 1.00 75.81  ? 80  ASP C N   1 
ATOM   6074  C CA  . ASP C 1 80  ? 85.525  108.644 172.561 1.00 75.81  ? 80  ASP C CA  1 
ATOM   6075  C C   . ASP C 1 80  ? 86.720  107.716 172.384 1.00 75.81  ? 80  ASP C C   1 
ATOM   6076  O O   . ASP C 1 80  ? 87.692  107.777 173.140 1.00 75.81  ? 80  ASP C O   1 
ATOM   6077  C CB  . ASP C 1 80  ? 85.770  109.967 171.837 1.00 75.81  ? 80  ASP C CB  1 
ATOM   6078  C CG  . ASP C 1 80  ? 85.488  109.878 170.352 1.00 75.81  ? 80  ASP C CG  1 
ATOM   6079  O OD1 . ASP C 1 80  ? 85.044  108.805 169.894 1.00 75.81  ? 80  ASP C OD1 1 
ATOM   6080  O OD2 . ASP C 1 80  ? 85.709  110.881 169.643 1.00 75.81  ? 80  ASP C OD2 1 
ATOM   6081  N N   . ASP C 1 81  ? 86.643  106.849 171.375 1.00 66.84  ? 81  ASP C N   1 
ATOM   6082  C CA  . ASP C 1 81  ? 87.699  105.869 171.138 1.00 66.84  ? 81  ASP C CA  1 
ATOM   6083  C C   . ASP C 1 81  ? 88.767  106.405 170.187 1.00 66.84  ? 81  ASP C C   1 
ATOM   6084  O O   . ASP C 1 81  ? 89.944  106.491 170.551 1.00 66.84  ? 81  ASP C O   1 
ATOM   6085  C CB  . ASP C 1 81  ? 87.096  104.568 170.595 1.00 66.84  ? 81  ASP C CB  1 
ATOM   6086  C CG  . ASP C 1 81  ? 86.120  104.805 169.459 1.00 66.84  ? 81  ASP C CG  1 
ATOM   6087  O OD1 . ASP C 1 81  ? 85.789  105.980 169.195 1.00 66.84  ? 81  ASP C OD1 1 
ATOM   6088  O OD2 . ASP C 1 81  ? 85.690  103.818 168.828 1.00 66.84  ? 81  ASP C OD2 1 
ATOM   6089  N N   . SER C 1 82  ? 88.372  106.772 168.969 1.00 55.65  ? 82  SER C N   1 
ATOM   6090  C CA  . SER C 1 82  ? 89.317  107.253 167.961 1.00 55.65  ? 82  SER C CA  1 
ATOM   6091  C C   . SER C 1 82  ? 89.567  108.746 168.168 1.00 55.65  ? 82  SER C C   1 
ATOM   6092  O O   . SER C 1 82  ? 89.186  109.601 167.367 1.00 55.65  ? 82  SER C O   1 
ATOM   6093  C CB  . SER C 1 82  ? 88.797  106.957 166.561 1.00 55.65  ? 82  SER C CB  1 
ATOM   6094  O OG  . SER C 1 82  ? 87.542  107.579 166.343 1.00 55.65  ? 82  SER C OG  1 
ATOM   6095  N N   . LEU C 1 83  ? 90.232  109.047 169.279 1.00 49.39  ? 83  LEU C N   1 
ATOM   6096  C CA  . LEU C 1 83  ? 90.534  110.426 169.652 1.00 49.39  ? 83  LEU C CA  1 
ATOM   6097  C C   . LEU C 1 83  ? 91.690  110.920 168.795 1.00 49.39  ? 83  LEU C C   1 
ATOM   6098  O O   . LEU C 1 83  ? 92.852  110.599 169.051 1.00 49.39  ? 83  LEU C O   1 
ATOM   6099  C CB  . LEU C 1 83  ? 90.868  110.517 171.134 1.00 49.39  ? 83  LEU C CB  1 
ATOM   6100  C CG  . LEU C 1 83  ? 91.210  111.911 171.654 1.00 49.39  ? 83  LEU C CG  1 
ATOM   6101  C CD1 . LEU C 1 83  ? 89.985  112.806 171.626 1.00 49.39  ? 83  LEU C CD1 1 
ATOM   6102  C CD2 . LEU C 1 83  ? 91.779  111.820 173.053 1.00 49.39  ? 83  LEU C CD2 1 
ATOM   6103  N N   . ASP C 1 84  ? 91.375  111.704 167.770 1.00 42.97  ? 84  ASP C N   1 
ATOM   6104  C CA  . ASP C 1 84  ? 92.408  112.255 166.908 1.00 42.97  ? 84  ASP C CA  1 
ATOM   6105  C C   . ASP C 1 84  ? 93.227  113.299 167.659 1.00 42.97  ? 84  ASP C C   1 
ATOM   6106  O O   . ASP C 1 84  ? 92.724  114.000 168.539 1.00 42.97  ? 84  ASP C O   1 
ATOM   6107  C CB  . ASP C 1 84  ? 91.785  112.872 165.659 1.00 42.97  ? 84  ASP C CB  1 
ATOM   6108  C CG  . ASP C 1 84  ? 92.739  112.893 164.487 1.00 42.97  ? 84  ASP C CG  1 
ATOM   6109  O OD1 . ASP C 1 84  ? 93.893  113.333 164.666 1.00 42.97  ? 84  ASP C OD1 1 
ATOM   6110  O OD2 . ASP C 1 84  ? 92.335  112.464 163.386 1.00 42.97  ? 84  ASP C OD2 1 
ATOM   6111  N N   . LEU C 1 85  ? 94.504  113.396 167.303 1.00 40.63  ? 85  LEU C N   1 
ATOM   6112  C CA  . LEU C 1 85  ? 95.427  114.304 167.965 1.00 40.63  ? 85  LEU C CA  1 
ATOM   6113  C C   . LEU C 1 85  ? 96.111  115.193 166.937 1.00 40.63  ? 85  LEU C C   1 
ATOM   6114  O O   . LEU C 1 85  ? 96.196  114.862 165.752 1.00 40.63  ? 85  LEU C O   1 
ATOM   6115  C CB  . LEU C 1 85  ? 96.486  113.549 168.779 1.00 40.63  ? 85  LEU C CB  1 
ATOM   6116  C CG  . LEU C 1 85  ? 96.205  113.390 170.273 1.00 40.63  ? 85  LEU C CG  1 
ATOM   6117  C CD1 . LEU C 1 85  ? 96.031  114.754 170.909 1.00 40.63  ? 85  LEU C CD1 1 
ATOM   6118  C CD2 . LEU C 1 85  ? 94.985  112.525 170.517 1.00 40.63  ? 85  LEU C CD2 1 
ATOM   6119  N N   . ASP C 1 86  ? 96.594  116.334 167.413 1.00 41.60  ? 86  ASP C N   1 
ATOM   6120  C CA  . ASP C 1 86  ? 97.300  117.261 166.545 1.00 41.60  ? 86  ASP C CA  1 
ATOM   6121  C C   . ASP C 1 86  ? 98.614  116.640 166.076 1.00 41.60  ? 86  ASP C C   1 
ATOM   6122  O O   . ASP C 1 86  ? 99.301  115.974 166.857 1.00 41.60  ? 86  ASP C O   1 
ATOM   6123  C CB  . ASP C 1 86  ? 97.567  118.576 167.277 1.00 41.60  ? 86  ASP C CB  1 
ATOM   6124  C CG  . ASP C 1 86  ? 98.095  119.661 166.359 1.00 41.60  ? 86  ASP C CG  1 
ATOM   6125  O OD1 . ASP C 1 86  ? 99.293  119.618 166.012 1.00 41.60  ? 86  ASP C OD1 1 
ATOM   6126  O OD2 . ASP C 1 86  ? 97.311  120.557 165.982 1.00 41.60  ? 86  ASP C OD2 1 
ATOM   6127  N N   . PRO C 1 87  ? 98.984  116.829 164.808 1.00 36.91  ? 87  PRO C N   1 
ATOM   6128  C CA  . PRO C 1 87  ? 100.231 116.230 164.307 1.00 36.91  ? 87  PRO C CA  1 
ATOM   6129  C C   . PRO C 1 87  ? 101.482 116.718 165.013 1.00 36.91  ? 87  PRO C C   1 
ATOM   6130  O O   . PRO C 1 87  ? 102.506 116.026 164.965 1.00 36.91  ? 87  PRO C O   1 
ATOM   6131  C CB  . PRO C 1 87  ? 100.239 116.629 162.826 1.00 36.91  ? 87  PRO C CB  1 
ATOM   6132  C CG  . PRO C 1 87  ? 98.813  116.888 162.494 1.00 36.91  ? 87  PRO C CG  1 
ATOM   6133  C CD  . PRO C 1 87  ? 98.198  117.455 163.733 1.00 36.91  ? 87  PRO C CD  1 
ATOM   6134  N N   . SER C 1 88  ? 101.443 117.885 165.660 1.00 41.14  ? 88  SER C N   1 
ATOM   6135  C CA  . SER C 1 88  ? 102.645 118.434 166.278 1.00 41.14  ? 88  SER C CA  1 
ATOM   6136  C C   . SER C 1 88  ? 103.120 117.615 167.472 1.00 41.14  ? 88  SER C C   1 
ATOM   6137  O O   . SER C 1 88  ? 104.281 117.748 167.871 1.00 41.14  ? 88  SER C O   1 
ATOM   6138  C CB  . SER C 1 88  ? 102.405 119.881 166.707 1.00 41.14  ? 88  SER C CB  1 
ATOM   6139  O OG  . SER C 1 88  ? 103.516 120.385 167.427 1.00 41.14  ? 88  SER C OG  1 
ATOM   6140  N N   . MET C 1 89  ? 102.258 116.776 168.050 1.00 46.38  ? 89  MET C N   1 
ATOM   6141  C CA  . MET C 1 89  ? 102.646 115.975 169.203 1.00 46.38  ? 89  MET C CA  1 
ATOM   6142  C C   . MET C 1 89  ? 103.619 114.858 168.853 1.00 46.38  ? 89  MET C C   1 
ATOM   6143  O O   . MET C 1 89  ? 104.174 114.236 169.765 1.00 46.38  ? 89  MET C O   1 
ATOM   6144  C CB  . MET C 1 89  ? 101.403 115.375 169.870 1.00 46.38  ? 89  MET C CB  1 
ATOM   6145  C CG  . MET C 1 89  ? 100.475 116.372 170.574 1.00 46.38  ? 89  MET C CG  1 
ATOM   6146  S SD  . MET C 1 89  ? 101.110 117.487 171.859 1.00 46.38  ? 89  MET C SD  1 
ATOM   6147  C CE  . MET C 1 89  ? 102.589 116.675 172.470 1.00 46.38  ? 89  MET C CE  1 
ATOM   6148  N N   . LEU C 1 90  ? 103.854 114.599 167.566 1.00 40.71  ? 90  LEU C N   1 
ATOM   6149  C CA  . LEU C 1 90  ? 104.680 113.472 167.153 1.00 40.71  ? 90  LEU C CA  1 
ATOM   6150  C C   . LEU C 1 90  ? 106.136 113.611 167.574 1.00 40.71  ? 90  LEU C C   1 
ATOM   6151  O O   . LEU C 1 90  ? 106.877 112.626 167.497 1.00 40.71  ? 90  LEU C O   1 
ATOM   6152  C CB  . LEU C 1 90  ? 104.595 113.295 165.639 1.00 40.71  ? 90  LEU C CB  1 
ATOM   6153  C CG  . LEU C 1 90  ? 103.303 112.646 165.147 1.00 40.71  ? 90  LEU C CG  1 
ATOM   6154  C CD1 . LEU C 1 90  ? 103.230 112.691 163.637 1.00 40.71  ? 90  LEU C CD1 1 
ATOM   6155  C CD2 . LEU C 1 90  ? 103.214 111.218 165.645 1.00 40.71  ? 90  LEU C CD2 1 
ATOM   6156  N N   . ASP C 1 91  ? 106.568 114.796 168.005 1.00 49.34  ? 91  ASP C N   1 
ATOM   6157  C CA  . ASP C 1 91  ? 107.938 114.945 168.473 1.00 49.34  ? 91  ASP C CA  1 
ATOM   6158  C C   . ASP C 1 91  ? 108.158 114.300 169.835 1.00 49.34  ? 91  ASP C C   1 
ATOM   6159  O O   . ASP C 1 91  ? 109.310 114.063 170.215 1.00 49.34  ? 91  ASP C O   1 
ATOM   6160  C CB  . ASP C 1 91  ? 108.319 116.425 168.528 1.00 49.34  ? 91  ASP C CB  1 
ATOM   6161  C CG  . ASP C 1 91  ? 108.335 117.074 167.158 1.00 49.34  ? 91  ASP C CG  1 
ATOM   6162  O OD1 . ASP C 1 91  ? 108.418 116.338 166.153 1.00 49.34  ? 91  ASP C OD1 1 
ATOM   6163  O OD2 . ASP C 1 91  ? 108.270 118.319 167.086 1.00 49.34  ? 91  ASP C OD2 1 
ATOM   6164  N N   . SER C 1 92  ? 107.091 114.007 170.573 1.00 47.79  ? 92  SER C N   1 
ATOM   6165  C CA  . SER C 1 92  ? 107.181 113.418 171.904 1.00 47.79  ? 92  SER C CA  1 
ATOM   6166  C C   . SER C 1 92  ? 106.451 112.082 171.965 1.00 47.79  ? 92  SER C C   1 
ATOM   6167  O O   . SER C 1 92  ? 105.797 111.754 172.956 1.00 47.79  ? 92  SER C O   1 
ATOM   6168  C CB  . SER C 1 92  ? 106.633 114.376 172.958 1.00 47.79  ? 92  SER C CB  1 
ATOM   6169  O OG  . SER C 1 92  ? 105.267 114.662 172.720 1.00 47.79  ? 92  SER C OG  1 
ATOM   6170  N N   . ILE C 1 93  ? 106.556 111.295 170.899 1.00 45.67  ? 93  ILE C N   1 
ATOM   6171  C CA  . ILE C 1 93  ? 105.932 109.979 170.822 1.00 45.67  ? 93  ILE C CA  1 
ATOM   6172  C C   . ILE C 1 93  ? 106.912 109.032 170.147 1.00 45.67  ? 93  ILE C C   1 
ATOM   6173  O O   . ILE C 1 93  ? 107.579 109.405 169.176 1.00 45.67  ? 93  ILE C O   1 
ATOM   6174  C CB  . ILE C 1 93  ? 104.589 110.039 170.064 1.00 45.67  ? 93  ILE C CB  1 
ATOM   6175  C CG1 . ILE C 1 93  ? 103.450 110.330 171.037 1.00 45.67  ? 93  ILE C CG1 1 
ATOM   6176  C CG2 . ILE C 1 93  ? 104.318 108.747 169.314 1.00 45.67  ? 93  ILE C CG2 1 
ATOM   6177  C CD1 . ILE C 1 93  ? 103.207 109.218 172.018 1.00 45.67  ? 93  ILE C CD1 1 
ATOM   6178  N N   . TRP C 1 94  ? 107.007 107.806 170.663 1.00 43.68  ? 94  TRP C N   1 
ATOM   6179  C CA  . TRP C 1 94  ? 107.930 106.831 170.095 1.00 43.68  ? 94  TRP C CA  1 
ATOM   6180  C C   . TRP C 1 94  ? 107.530 106.479 168.670 1.00 43.68  ? 94  TRP C C   1 
ATOM   6181  O O   . TRP C 1 94  ? 106.546 105.767 168.453 1.00 43.68  ? 94  TRP C O   1 
ATOM   6182  C CB  . TRP C 1 94  ? 107.978 105.565 170.948 1.00 43.68  ? 94  TRP C CB  1 
ATOM   6183  C CG  . TRP C 1 94  ? 108.962 104.560 170.442 1.00 43.68  ? 94  TRP C CG  1 
ATOM   6184  C CD1 . TRP C 1 94  ? 110.309 104.569 170.635 1.00 43.68  ? 94  TRP C CD1 1 
ATOM   6185  C CD2 . TRP C 1 94  ? 108.678 103.402 169.649 1.00 43.68  ? 94  TRP C CD2 1 
ATOM   6186  N NE1 . TRP C 1 94  ? 110.884 103.487 170.016 1.00 43.68  ? 94  TRP C NE1 1 
ATOM   6187  C CE2 . TRP C 1 94  ? 109.902 102.755 169.404 1.00 43.68  ? 94  TRP C CE2 1 
ATOM   6188  C CE3 . TRP C 1 94  ? 107.508 102.849 169.126 1.00 43.68  ? 94  TRP C CE3 1 
ATOM   6189  C CZ2 . TRP C 1 94  ? 109.990 101.585 168.658 1.00 43.68  ? 94  TRP C CZ2 1 
ATOM   6190  C CZ3 . TRP C 1 94  ? 107.598 101.686 168.387 1.00 43.68  ? 94  TRP C CZ3 1 
ATOM   6191  C CH2 . TRP C 1 94  ? 108.829 101.067 168.160 1.00 43.68  ? 94  TRP C CH2 1 
ATOM   6192  N N   . LYS C 1 95  ? 108.288 106.975 167.695 1.00 38.91  ? 95  LYS C N   1 
ATOM   6193  C CA  . LYS C 1 95  ? 108.030 106.680 166.296 1.00 38.91  ? 95  LYS C CA  1 
ATOM   6194  C C   . LYS C 1 95  ? 108.935 105.547 165.850 1.00 38.91  ? 95  LYS C C   1 
ATOM   6195  O O   . LYS C 1 95  ? 110.165 105.693 165.919 1.00 38.91  ? 95  LYS C O   1 
ATOM   6196  C CB  . LYS C 1 95  ? 108.270 107.913 165.435 1.00 38.91  ? 95  LYS C CB  1 
ATOM   6197  C CG  . LYS C 1 95  ? 107.469 109.130 165.854 1.00 38.91  ? 95  LYS C CG  1 
ATOM   6198  C CD  . LYS C 1 95  ? 108.199 110.419 165.510 1.00 38.91  ? 95  LYS C CD  1 
ATOM   6199  C CE  . LYS C 1 95  ? 108.775 110.381 164.103 1.00 38.91  ? 95  LYS C CE  1 
ATOM   6200  N NZ  . LYS C 1 95  ? 107.729 110.131 163.076 1.00 38.91  ? 95  LYS C NZ  1 
ATOM   6201  N N   . PRO C 1 96  ? 108.396 104.415 165.406 1.00 36.07  ? 96  PRO C N   1 
ATOM   6202  C CA  . PRO C 1 96  ? 109.260 103.312 164.978 1.00 36.07  ? 96  PRO C CA  1 
ATOM   6203  C C   . PRO C 1 96  ? 110.121 103.712 163.791 1.00 36.07  ? 96  PRO C C   1 
ATOM   6204  O O   . PRO C 1 96  ? 109.677 104.422 162.887 1.00 36.07  ? 96  PRO C O   1 
ATOM   6205  C CB  . PRO C 1 96  ? 108.266 102.208 164.606 1.00 36.07  ? 96  PRO C CB  1 
ATOM   6206  C CG  . PRO C 1 96  ? 107.017 102.934 164.268 1.00 36.07  ? 96  PRO C CG  1 
ATOM   6207  C CD  . PRO C 1 96  ? 106.973 104.115 165.188 1.00 36.07  ? 96  PRO C CD  1 
ATOM   6208  N N   . ASP C 1 97  ? 111.367 103.249 163.806 1.00 40.64  ? 97  ASP C N   1 
ATOM   6209  C CA  . ASP C 1 97  ? 112.273 103.499 162.697 1.00 40.64  ? 97  ASP C CA  1 
ATOM   6210  C C   . ASP C 1 97  ? 111.796 102.760 161.456 1.00 40.64  ? 97  ASP C C   1 
ATOM   6211  O O   . ASP C 1 97  ? 111.306 101.631 161.535 1.00 40.64  ? 97  ASP C O   1 
ATOM   6212  C CB  . ASP C 1 97  ? 113.691 103.062 163.064 1.00 40.64  ? 97  ASP C CB  1 
ATOM   6213  C CG  . ASP C 1 97  ? 114.672 103.200 161.910 1.00 40.64  ? 97  ASP C CG  1 
ATOM   6214  O OD1 . ASP C 1 97  ? 114.341 103.852 160.898 1.00 40.64  ? 97  ASP C OD1 1 
ATOM   6215  O OD2 . ASP C 1 97  ? 115.788 102.650 162.019 1.00 40.64  ? 97  ASP C OD2 1 
ATOM   6216  N N   . LEU C 1 98  ? 111.947 103.406 160.303 1.00 36.13  ? 98  LEU C N   1 
ATOM   6217  C CA  . LEU C 1 98  ? 111.584 102.792 159.034 1.00 36.13  ? 98  LEU C CA  1 
ATOM   6218  C C   . LEU C 1 98  ? 112.228 103.592 157.917 1.00 36.13  ? 98  LEU C C   1 
ATOM   6219  O O   . LEU C 1 98  ? 112.044 104.809 157.843 1.00 36.13  ? 98  LEU C O   1 
ATOM   6220  C CB  . LEU C 1 98  ? 110.063 102.741 158.857 1.00 36.13  ? 98  LEU C CB  1 
ATOM   6221  C CG  . LEU C 1 98  ? 109.504 102.433 157.468 1.00 36.13  ? 98  LEU C CG  1 
ATOM   6222  C CD1 . LEU C 1 98  ? 108.243 101.609 157.604 1.00 36.13  ? 98  LEU C CD1 1 
ATOM   6223  C CD2 . LEU C 1 98  ? 109.209 103.703 156.693 1.00 36.13  ? 98  LEU C CD2 1 
ATOM   6224  N N   . PHE C 1 99  ? 112.972 102.912 157.054 1.00 33.82  ? 99  PHE C N   1 
ATOM   6225  C CA  . PHE C 1 99  ? 113.570 103.554 155.897 1.00 33.82  ? 99  PHE C CA  1 
ATOM   6226  C C   . PHE C 1 99  ? 113.481 102.605 154.714 1.00 33.82  ? 99  PHE C C   1 
ATOM   6227  O O   . PHE C 1 99  ? 113.374 101.388 154.873 1.00 33.82  ? 99  PHE C O   1 
ATOM   6228  C CB  . PHE C 1 99  ? 115.025 103.958 156.155 1.00 33.82  ? 99  PHE C CB  1 
ATOM   6229  C CG  . PHE C 1 99  ? 116.017 102.872 155.868 1.00 33.82  ? 99  PHE C CG  1 
ATOM   6230  C CD1 . PHE C 1 99  ? 116.160 101.799 156.725 1.00 33.82  ? 99  PHE C CD1 1 
ATOM   6231  C CD2 . PHE C 1 99  ? 116.817 102.930 154.742 1.00 33.82  ? 99  PHE C CD2 1 
ATOM   6232  C CE1 . PHE C 1 99  ? 117.076 100.804 156.463 1.00 33.82  ? 99  PHE C CE1 1 
ATOM   6233  C CE2 . PHE C 1 99  ? 117.732 101.937 154.475 1.00 33.82  ? 99  PHE C CE2 1 
ATOM   6234  C CZ  . PHE C 1 99  ? 117.861 100.875 155.338 1.00 33.82  ? 99  PHE C CZ  1 
ATOM   6235  N N   . PHE C 1 100 ? 113.525 103.180 153.520 1.00 33.87  ? 100 PHE C N   1 
ATOM   6236  C CA  . PHE C 1 100 ? 113.392 102.417 152.288 1.00 33.87  ? 100 PHE C CA  1 
ATOM   6237  C C   . PHE C 1 100 ? 114.778 102.017 151.800 1.00 33.87  ? 100 PHE C C   1 
ATOM   6238  O O   . PHE C 1 100 ? 115.644 102.875 151.604 1.00 33.87  ? 100 PHE C O   1 
ATOM   6239  C CB  . PHE C 1 100 ? 112.642 103.237 151.241 1.00 33.87  ? 100 PHE C CB  1 
ATOM   6240  C CG  . PHE C 1 100 ? 111.255 103.626 151.666 1.00 33.87  ? 100 PHE C CG  1 
ATOM   6241  C CD1 . PHE C 1 100 ? 111.051 104.671 152.548 1.00 33.87  ? 100 PHE C CD1 1 
ATOM   6242  C CD2 . PHE C 1 100 ? 110.154 102.946 151.180 1.00 33.87  ? 100 PHE C CD2 1 
ATOM   6243  C CE1 . PHE C 1 100 ? 109.776 105.026 152.940 1.00 33.87  ? 100 PHE C CE1 1 
ATOM   6244  C CE2 . PHE C 1 100 ? 108.878 103.300 151.568 1.00 33.87  ? 100 PHE C CE2 1 
ATOM   6245  C CZ  . PHE C 1 100 ? 108.690 104.341 152.448 1.00 33.87  ? 100 PHE C CZ  1 
ATOM   6246  N N   . ALA C 1 101 ? 114.988 100.712 151.622 1.00 33.30  ? 101 ALA C N   1 
ATOM   6247  C CA  . ALA C 1 101 ? 116.320 100.215 151.292 1.00 33.30  ? 101 ALA C CA  1 
ATOM   6248  C C   . ALA C 1 101 ? 116.786 100.721 149.935 1.00 33.30  ? 101 ALA C C   1 
ATOM   6249  O O   . ALA C 1 101 ? 117.957 101.078 149.768 1.00 33.30  ? 101 ALA C O   1 
ATOM   6250  C CB  . ALA C 1 101 ? 116.336 98.689  151.328 1.00 33.30  ? 101 ALA C CB  1 
ATOM   6251  N N   . ASN C 1 102 ? 115.893 100.755 148.953 1.00 35.11  ? 102 ASN C N   1 
ATOM   6252  C CA  . ASN C 1 102 ? 116.235 101.166 147.595 1.00 35.11  ? 102 ASN C CA  1 
ATOM   6253  C C   . ASN C 1 102 ? 115.556 102.499 147.301 1.00 35.11  ? 102 ASN C C   1 
ATOM   6254  O O   . ASN C 1 102 ? 114.378 102.540 146.936 1.00 35.11  ? 102 ASN C O   1 
ATOM   6255  C CB  . ASN C 1 102 ? 115.828 100.097 146.587 1.00 35.11  ? 102 ASN C CB  1 
ATOM   6256  C CG  . ASN C 1 102 ? 114.388 99.666  146.747 1.00 35.11  ? 102 ASN C CG  1 
ATOM   6257  O OD1 . ASN C 1 102 ? 113.925 99.416  147.858 1.00 35.11  ? 102 ASN C OD1 1 
ATOM   6258  N ND2 . ASN C 1 102 ? 113.667 99.587  145.637 1.00 35.11  ? 102 ASN C ND2 1 
ATOM   6259  N N   . GLU C 1 103 ? 116.301 103.591 147.459 1.00 35.78  ? 103 GLU C N   1 
ATOM   6260  C CA  . GLU C 1 103 ? 115.796 104.911 147.093 1.00 35.78  ? 103 GLU C CA  1 
ATOM   6261  C C   . GLU C 1 103 ? 116.977 105.848 146.909 1.00 35.78  ? 103 GLU C C   1 
ATOM   6262  O O   . GLU C 1 103 ? 117.759 106.048 147.842 1.00 35.78  ? 103 GLU C O   1 
ATOM   6263  C CB  . GLU C 1 103 ? 114.831 105.446 148.151 1.00 35.78  ? 103 GLU C CB  1 
ATOM   6264  C CG  . GLU C 1 103 ? 115.307 105.304 149.578 1.00 35.78  ? 103 GLU C CG  1 
ATOM   6265  C CD  . GLU C 1 103 ? 115.775 106.619 150.157 1.00 35.78  ? 103 GLU C CD  1 
ATOM   6266  O OE1 . GLU C 1 103 ? 115.785 107.621 149.413 1.00 35.78  ? 103 GLU C OE1 1 
ATOM   6267  O OE2 . GLU C 1 103 ? 116.132 106.653 151.354 1.00 35.78  ? 103 GLU C OE2 1 
ATOM   6268  N N   . LYS C 1 104 ? 117.112 106.414 145.710 1.00 33.07  ? 104 LYS C N   1 
ATOM   6269  C CA  . LYS C 1 104 ? 118.183 107.364 145.447 1.00 33.07  ? 104 LYS C CA  1 
ATOM   6270  C C   . LYS C 1 104 ? 117.941 108.714 146.104 1.00 33.07  ? 104 LYS C C   1 
ATOM   6271  O O   . LYS C 1 104 ? 118.848 109.552 146.109 1.00 33.07  ? 104 LYS C O   1 
ATOM   6272  C CB  . LYS C 1 104 ? 118.363 107.546 143.940 1.00 33.07  ? 104 LYS C CB  1 
ATOM   6273  C CG  . LYS C 1 104 ? 118.201 106.265 143.142 1.00 33.07  ? 104 LYS C CG  1 
ATOM   6274  C CD  . LYS C 1 104 ? 118.227 106.533 141.649 1.00 33.07  ? 104 LYS C CD  1 
ATOM   6275  C CE  . LYS C 1 104 ? 119.649 106.594 141.124 1.00 33.07  ? 104 LYS C CE  1 
ATOM   6276  N NZ  . LYS C 1 104 ? 120.359 105.298 141.301 1.00 33.07  ? 104 LYS C NZ  1 
ATOM   6277  N N   . GLY C 1 105 ? 116.751 108.946 146.646 1.00 30.06  ? 105 GLY C N   1 
ATOM   6278  C CA  . GLY C 1 105 ? 116.452 110.187 147.329 1.00 30.06  ? 105 GLY C CA  1 
ATOM   6279  C C   . GLY C 1 105 ? 114.985 110.313 147.678 1.00 30.06  ? 105 GLY C C   1 
ATOM   6280  O O   . GLY C 1 105 ? 114.117 110.010 146.855 1.00 30.06  ? 105 GLY C O   1 
ATOM   6281  N N   . ALA C 1 106 ? 114.693 110.760 148.896 1.00 27.84  ? 106 ALA C N   1 
ATOM   6282  C CA  . ALA C 1 106 ? 113.317 110.921 149.335 1.00 27.84  ? 106 ALA C CA  1 
ATOM   6283  C C   . ALA C 1 106 ? 113.243 112.095 150.298 1.00 27.84  ? 106 ALA C C   1 
ATOM   6284  O O   . ALA C 1 106 ? 114.218 112.432 150.972 1.00 27.84  ? 106 ALA C O   1 
ATOM   6285  C CB  . ALA C 1 106 ? 112.782 109.646 149.992 1.00 27.84  ? 106 ALA C CB  1 
ATOM   6286  N N   . ASN C 1 107 ? 112.067 112.713 150.358 1.00 28.94  ? 107 ASN C N   1 
ATOM   6287  C CA  . ASN C 1 107 ? 111.886 113.915 151.155 1.00 28.94  ? 107 ASN C CA  1 
ATOM   6288  C C   . ASN C 1 107 ? 110.476 113.939 151.718 1.00 28.94  ? 107 ASN C C   1 
ATOM   6289  O O   . ASN C 1 107 ? 109.559 113.318 151.178 1.00 28.94  ? 107 ASN C O   1 
ATOM   6290  C CB  . ASN C 1 107 ? 112.137 115.176 150.328 1.00 28.94  ? 107 ASN C CB  1 
ATOM   6291  C CG  . ASN C 1 107 ? 111.151 115.326 149.193 1.00 28.94  ? 107 ASN C CG  1 
ATOM   6292  O OD1 . ASN C 1 107 ? 110.633 114.338 148.676 1.00 28.94  ? 107 ASN C OD1 1 
ATOM   6293  N ND2 . ASN C 1 107 ? 110.882 116.563 148.800 1.00 28.94  ? 107 ASN C ND2 1 
ATOM   6294  N N   . PHE C 1 108 ? 110.311 114.684 152.806 1.00 33.16  ? 108 PHE C N   1 
ATOM   6295  C CA  . PHE C 1 108 ? 108.999 114.881 153.404 1.00 33.16  ? 108 PHE C CA  1 
ATOM   6296  C C   . PHE C 1 108 ? 108.223 115.892 152.567 1.00 33.16  ? 108 PHE C C   1 
ATOM   6297  O O   . PHE C 1 108 ? 108.645 116.295 151.480 1.00 33.16  ? 108 PHE C O   1 
ATOM   6298  C CB  . PHE C 1 108 ? 109.129 115.345 154.850 1.00 33.16  ? 108 PHE C CB  1 
ATOM   6299  C CG  . PHE C 1 108 ? 109.795 114.356 155.753 1.00 33.16  ? 108 PHE C CG  1 
ATOM   6300  C CD1 . PHE C 1 108 ? 111.170 114.345 155.891 1.00 33.16  ? 108 PHE C CD1 1 
ATOM   6301  C CD2 . PHE C 1 108 ? 109.047 113.451 156.480 1.00 33.16  ? 108 PHE C CD2 1 
ATOM   6302  C CE1 . PHE C 1 108 ? 111.785 113.443 156.727 1.00 33.16  ? 108 PHE C CE1 1 
ATOM   6303  C CE2 . PHE C 1 108 ? 109.659 112.547 157.318 1.00 33.16  ? 108 PHE C CE2 1 
ATOM   6304  C CZ  . PHE C 1 108 ? 111.028 112.543 157.442 1.00 33.16  ? 108 PHE C CZ  1 
ATOM   6305  N N   . HIS C 1 109 ? 107.070 116.317 153.070 1.00 36.94  ? 109 HIS C N   1 
ATOM   6306  C CA  . HIS C 1 109 ? 106.293 117.362 152.425 1.00 36.94  ? 109 HIS C CA  1 
ATOM   6307  C C   . HIS C 1 109 ? 105.747 118.296 153.489 1.00 36.94  ? 109 HIS C C   1 
ATOM   6308  O O   . HIS C 1 109 ? 105.088 117.847 154.432 1.00 36.94  ? 109 HIS C O   1 
ATOM   6309  C CB  . HIS C 1 109 ? 105.149 116.774 151.598 1.00 36.94  ? 109 HIS C CB  1 
ATOM   6310  C CG  . HIS C 1 109 ? 105.471 116.628 150.146 1.00 36.94  ? 109 HIS C CG  1 
ATOM   6311  N ND1 . HIS C 1 109 ? 104.759 115.801 149.306 1.00 36.94  ? 109 HIS C ND1 1 
ATOM   6312  C CD2 . HIS C 1 109 ? 106.427 117.207 149.382 1.00 36.94  ? 109 HIS C CD2 1 
ATOM   6313  C CE1 . HIS C 1 109 ? 105.263 115.875 148.087 1.00 36.94  ? 109 HIS C CE1 1 
ATOM   6314  N NE2 . HIS C 1 109 ? 106.277 116.721 148.107 1.00 36.94  ? 109 HIS C NE2 1 
ATOM   6315  N N   . GLU C 1 110 ? 106.024 119.588 153.340 1.00 37.19  ? 110 GLU C N   1 
ATOM   6316  C CA  . GLU C 1 110 ? 105.492 120.607 154.234 1.00 37.19  ? 110 GLU C CA  1 
ATOM   6317  C C   . GLU C 1 110 ? 104.893 121.727 153.397 1.00 37.19  ? 110 GLU C C   1 
ATOM   6318  O O   . GLU C 1 110 ? 105.564 122.288 152.525 1.00 37.19  ? 110 GLU C O   1 
ATOM   6319  C CB  . GLU C 1 110 ? 106.573 121.124 155.197 1.00 37.19  ? 110 GLU C CB  1 
ATOM   6320  C CG  . GLU C 1 110 ? 107.617 122.066 154.608 1.00 37.19  ? 110 GLU C CG  1 
ATOM   6321  C CD  . GLU C 1 110 ? 108.656 121.351 153.764 1.00 37.19  ? 110 GLU C CD  1 
ATOM   6322  O OE1 . GLU C 1 110 ? 108.497 120.139 153.512 1.00 37.19  ? 110 GLU C OE1 1 
ATOM   6323  O OE2 . GLU C 1 110 ? 109.633 122.007 153.343 1.00 37.19  ? 110 GLU C OE2 1 
ATOM   6324  N N   . VAL C 1 111 ? 103.611 122.004 153.618 1.00 34.39  ? 111 VAL C N   1 
ATOM   6325  C CA  . VAL C 1 111 ? 102.930 123.144 153.017 1.00 34.39  ? 111 VAL C CA  1 
ATOM   6326  C C   . VAL C 1 111 ? 101.900 123.626 154.028 1.00 34.39  ? 111 VAL C C   1 
ATOM   6327  O O   . VAL C 1 111 ? 100.936 122.911 154.322 1.00 34.39  ? 111 VAL C O   1 
ATOM   6328  C CB  . VAL C 1 111 ? 102.262 122.798 151.682 1.00 34.39  ? 111 VAL C CB  1 
ATOM   6329  C CG1 . VAL C 1 111 ? 103.200 123.111 150.534 1.00 34.39  ? 111 VAL C CG1 1 
ATOM   6330  C CG2 . VAL C 1 111 ? 101.866 121.332 151.658 1.00 34.39  ? 111 VAL C CG2 1 
ATOM   6331  N N   . THR C 1 112 ? 102.125 124.816 154.587 1.00 37.68  ? 112 THR C N   1 
ATOM   6332  C CA  . THR C 1 112 ? 101.269 125.446 155.591 1.00 37.68  ? 112 THR C CA  1 
ATOM   6333  C C   . THR C 1 112 ? 101.275 124.657 156.897 1.00 37.68  ? 112 THR C C   1 
ATOM   6334  O O   . THR C 1 112 ? 100.731 125.118 157.906 1.00 37.68  ? 112 THR C O   1 
ATOM   6335  C CB  . THR C 1 112 ? 99.833  125.612 155.078 1.00 37.68  ? 112 THR C CB  1 
ATOM   6336  O OG1 . THR C 1 112 ? 99.220  124.326 154.932 1.00 37.68  ? 112 THR C OG1 1 
ATOM   6337  C CG2 . THR C 1 112 ? 99.822  126.327 153.739 1.00 37.68  ? 112 THR C CG2 1 
ATOM   6338  N N   . THR C 1 113 ? 101.911 123.485 156.887 1.00 40.29  ? 113 THR C N   1 
ATOM   6339  C CA  . THR C 1 113 ? 102.032 122.606 158.044 1.00 40.29  ? 113 THR C CA  1 
ATOM   6340  C C   . THR C 1 113 ? 102.862 121.392 157.656 1.00 40.29  ? 113 THR C C   1 
ATOM   6341  O O   . THR C 1 113 ? 103.288 121.273 156.503 1.00 40.29  ? 113 THR C O   1 
ATOM   6342  C CB  . THR C 1 113 ? 100.664 122.160 158.557 1.00 40.29  ? 113 THR C CB  1 
ATOM   6343  O OG1 . THR C 1 113 ? 100.805 121.598 159.867 1.00 40.29  ? 113 THR C OG1 1 
ATOM   6344  C CG2 . THR C 1 113 ? 100.072 121.122 157.630 1.00 40.29  ? 113 THR C CG2 1 
ATOM   6345  N N   . ASP C 1 114 ? 103.095 120.485 158.598 1.00 39.63  ? 114 ASP C N   1 
ATOM   6346  C CA  . ASP C 1 114 ? 103.739 119.217 158.295 1.00 39.63  ? 114 ASP C CA  1 
ATOM   6347  C C   . ASP C 1 114 ? 102.671 118.168 158.015 1.00 39.63  ? 114 ASP C C   1 
ATOM   6348  O O   . ASP C 1 114 ? 101.755 117.978 158.820 1.00 39.63  ? 114 ASP C O   1 
ATOM   6349  C CB  . ASP C 1 114 ? 104.638 118.774 159.448 1.00 39.63  ? 114 ASP C CB  1 
ATOM   6350  C CG  . ASP C 1 114 ? 105.957 118.211 158.969 1.00 39.63  ? 114 ASP C CG  1 
ATOM   6351  O OD1 . ASP C 1 114 ? 106.083 117.950 157.754 1.00 39.63  ? 114 ASP C OD1 1 
ATOM   6352  O OD2 . ASP C 1 114 ? 106.871 118.037 159.801 1.00 39.63  ? 114 ASP C OD2 1 
ATOM   6353  N N   . ASN C 1 115 ? 102.790 117.494 156.871 1.00 35.72  ? 115 ASN C N   1 
ATOM   6354  C CA  . ASN C 1 115 ? 101.783 116.529 156.430 1.00 35.72  ? 115 ASN C CA  1 
ATOM   6355  C C   . ASN C 1 115 ? 101.950 115.234 157.219 1.00 35.72  ? 115 ASN C C   1 
ATOM   6356  O O   . ASN C 1 115 ? 102.612 114.285 156.796 1.00 35.72  ? 115 ASN C O   1 
ATOM   6357  C CB  . ASN C 1 115 ? 101.895 116.291 154.932 1.00 35.72  ? 115 ASN C CB  1 
ATOM   6358  C CG  . ASN C 1 115 ? 101.531 117.513 154.128 1.00 35.72  ? 115 ASN C CG  1 
ATOM   6359  O OD1 . ASN C 1 115 ? 101.098 118.521 154.680 1.00 35.72  ? 115 ASN C OD1 1 
ATOM   6360  N ND2 . ASN C 1 115 ? 101.703 117.433 152.815 1.00 35.72  ? 115 ASN C ND2 1 
ATOM   6361  N N   . LYS C 1 116 ? 101.329 115.202 158.394 1.00 31.22  ? 116 LYS C N   1 
ATOM   6362  C CA  . LYS C 1 116 ? 101.351 114.031 159.255 1.00 31.22  ? 116 LYS C CA  1 
ATOM   6363  C C   . LYS C 1 116 ? 99.985  113.866 159.900 1.00 31.22  ? 116 LYS C C   1 
ATOM   6364  O O   . LYS C 1 116 ? 99.211  114.818 160.014 1.00 31.22  ? 116 LYS C O   1 
ATOM   6365  C CB  . LYS C 1 116 ? 102.434 114.137 160.336 1.00 31.22  ? 116 LYS C CB  1 
ATOM   6366  C CG  . LYS C 1 116 ? 103.858 114.089 159.809 1.00 31.22  ? 116 LYS C CG  1 
ATOM   6367  C CD  . LYS C 1 116 ? 104.859 114.423 160.901 1.00 31.22  ? 116 LYS C CD  1 
ATOM   6368  C CE  . LYS C 1 116 ? 106.287 114.337 160.392 1.00 31.22  ? 116 LYS C CE  1 
ATOM   6369  N NZ  . LYS C 1 116 ? 107.275 114.623 161.468 1.00 31.22  ? 116 LYS C NZ  1 
ATOM   6370  N N   . LEU C 1 117 ? 99.691  112.639 160.319 1.00 30.02  ? 117 LEU C N   1 
ATOM   6371  C CA  . LEU C 1 117 ? 98.435  112.334 160.990 1.00 30.02  ? 117 LEU C CA  1 
ATOM   6372  C C   . LEU C 1 117 ? 98.707  111.384 162.143 1.00 30.02  ? 117 LEU C C   1 
ATOM   6373  O O   . LEU C 1 117 ? 99.407  110.384 161.973 1.00 30.02  ? 117 LEU C O   1 
ATOM   6374  C CB  . LEU C 1 117 ? 97.424  111.711 160.025 1.00 30.02  ? 117 LEU C CB  1 
ATOM   6375  C CG  . LEU C 1 117 ? 96.264  110.953 160.667 1.00 30.02  ? 117 LEU C CG  1 
ATOM   6376  C CD1 . LEU C 1 117 ? 95.331  111.913 161.375 1.00 30.02  ? 117 LEU C CD1 1 
ATOM   6377  C CD2 . LEU C 1 117 ? 95.510  110.147 159.629 1.00 30.02  ? 117 LEU C CD2 1 
ATOM   6378  N N   . LEU C 1 118 ? 98.151  111.696 163.308 1.00 34.36  ? 118 LEU C N   1 
ATOM   6379  C CA  . LEU C 1 118 ? 98.295  110.867 164.493 1.00 34.36  ? 118 LEU C CA  1 
ATOM   6380  C C   . LEU C 1 118 ? 96.916  110.567 165.056 1.00 34.36  ? 118 LEU C C   1 
ATOM   6381  O O   . LEU C 1 118 ? 96.048  111.443 165.089 1.00 34.36  ? 118 LEU C O   1 
ATOM   6382  C CB  . LEU C 1 118 ? 99.160  111.556 165.549 1.00 34.36  ? 118 LEU C CB  1 
ATOM   6383  C CG  . LEU C 1 118 ? 99.305  110.838 166.888 1.00 34.36  ? 118 LEU C CG  1 
ATOM   6384  C CD1 . LEU C 1 118 ? 100.121 109.578 166.720 1.00 34.36  ? 118 LEU C CD1 1 
ATOM   6385  C CD2 . LEU C 1 118 ? 99.938  111.750 167.919 1.00 34.36  ? 118 LEU C CD2 1 
ATOM   6386  N N   . ARG C 1 119 ? 96.714  109.326 165.491 1.00 36.79  ? 119 ARG C N   1 
ATOM   6387  C CA  . ARG C 1 119 ? 95.426  108.905 166.024 1.00 36.79  ? 119 ARG C CA  1 
ATOM   6388  C C   . ARG C 1 119 ? 95.662  107.841 167.083 1.00 36.79  ? 119 ARG C C   1 
ATOM   6389  O O   . ARG C 1 119 ? 96.353  106.854 166.822 1.00 36.79  ? 119 ARG C O   1 
ATOM   6390  C CB  . ARG C 1 119 ? 94.524  108.369 164.909 1.00 36.79  ? 119 ARG C CB  1 
ATOM   6391  C CG  . ARG C 1 119 ? 93.350  107.545 165.392 1.00 36.79  ? 119 ARG C CG  1 
ATOM   6392  C CD  . ARG C 1 119 ? 92.476  107.105 164.228 1.00 36.79  ? 119 ARG C CD  1 
ATOM   6393  N NE  . ARG C 1 119 ? 91.600  108.174 163.765 1.00 36.79  ? 119 ARG C NE  1 
ATOM   6394  C CZ  . ARG C 1 119 ? 91.793  108.872 162.654 1.00 36.79  ? 119 ARG C CZ  1 
ATOM   6395  N NH1 . ARG C 1 119 ? 92.823  108.636 161.860 1.00 36.79  ? 119 ARG C NH1 1 
ATOM   6396  N NH2 . ARG C 1 119 ? 90.929  109.830 162.332 1.00 36.79  ? 119 ARG C NH2 1 
ATOM   6397  N N   . ILE C 1 120 ? 95.086  108.040 168.266 1.00 40.92  ? 120 ILE C N   1 
ATOM   6398  C CA  . ILE C 1 120 ? 95.290  107.155 169.406 1.00 40.92  ? 120 ILE C CA  1 
ATOM   6399  C C   . ILE C 1 120 ? 93.955  106.533 169.786 1.00 40.92  ? 120 ILE C C   1 
ATOM   6400  O O   . ILE C 1 120 ? 92.960  107.245 169.960 1.00 40.92  ? 120 ILE C O   1 
ATOM   6401  C CB  . ILE C 1 120 ? 95.898  107.902 170.605 1.00 40.92  ? 120 ILE C CB  1 
ATOM   6402  C CG1 . ILE C 1 120 ? 97.360  108.243 170.334 1.00 40.92  ? 120 ILE C CG1 1 
ATOM   6403  C CG2 . ILE C 1 120 ? 95.781  107.070 171.864 1.00 40.92  ? 120 ILE C CG2 1 
ATOM   6404  C CD1 . ILE C 1 120 ? 97.584  109.685 169.973 1.00 40.92  ? 120 ILE C CD1 1 
ATOM   6405  N N   . PHE C 1 121 ? 93.937  105.211 169.918 1.00 47.60  ? 121 PHE C N   1 
ATOM   6406  C CA  . PHE C 1 121 ? 92.752  104.478 170.335 1.00 47.60  ? 121 PHE C CA  1 
ATOM   6407  C C   . PHE C 1 121 ? 92.802  104.198 171.834 1.00 47.60  ? 121 PHE C C   1 
ATOM   6408  O O   . PHE C 1 121 ? 93.822  104.395 172.497 1.00 47.60  ? 121 PHE C O   1 
ATOM   6409  C CB  . PHE C 1 121 ? 92.625  103.171 169.548 1.00 47.60  ? 121 PHE C CB  1 
ATOM   6410  C CG  . PHE C 1 121 ? 92.434  103.369 168.075 1.00 47.60  ? 121 PHE C CG  1 
ATOM   6411  C CD1 . PHE C 1 121 ? 93.523  103.515 167.236 1.00 47.60  ? 121 PHE C CD1 1 
ATOM   6412  C CD2 . PHE C 1 121 ? 91.165  103.407 167.528 1.00 47.60  ? 121 PHE C CD2 1 
ATOM   6413  C CE1 . PHE C 1 121 ? 93.350  103.697 165.881 1.00 47.60  ? 121 PHE C CE1 1 
ATOM   6414  C CE2 . PHE C 1 121 ? 90.987  103.588 166.173 1.00 47.60  ? 121 PHE C CE2 1 
ATOM   6415  C CZ  . PHE C 1 121 ? 92.082  103.733 165.349 1.00 47.60  ? 121 PHE C CZ  1 
ATOM   6416  N N   . LYS C 1 122 ? 91.670  103.735 172.367 1.00 61.68  ? 122 LYS C N   1 
ATOM   6417  C CA  . LYS C 1 122 ? 91.577  103.484 173.802 1.00 61.68  ? 122 LYS C CA  1 
ATOM   6418  C C   . LYS C 1 122 ? 92.512  102.364 174.239 1.00 61.68  ? 122 LYS C C   1 
ATOM   6419  O O   . LYS C 1 122 ? 93.178  102.474 175.275 1.00 61.68  ? 122 LYS C O   1 
ATOM   6420  C CB  . LYS C 1 122 ? 90.136  103.152 174.186 1.00 61.68  ? 122 LYS C CB  1 
ATOM   6421  C CG  . LYS C 1 122 ? 89.191  104.336 174.133 1.00 61.68  ? 122 LYS C CG  1 
ATOM   6422  C CD  . LYS C 1 122 ? 87.818  103.962 174.661 1.00 61.68  ? 122 LYS C CD  1 
ATOM   6423  C CE  . LYS C 1 122 ? 87.861  103.663 176.150 1.00 61.68  ? 122 LYS C CE  1 
ATOM   6424  N NZ  . LYS C 1 122 ? 88.112  104.889 176.955 1.00 61.68  ? 122 LYS C NZ  1 
ATOM   6425  N N   . ASN C 1 123 ? 92.578  101.278 173.468 1.00 54.72  ? 123 ASN C N   1 
ATOM   6426  C CA  . ASN C 1 123 ? 93.381  100.129 173.869 1.00 54.72  ? 123 ASN C CA  1 
ATOM   6427  C C   . ASN C 1 123 ? 94.880  100.385 173.779 1.00 54.72  ? 123 ASN C C   1 
ATOM   6428  O O   . ASN C 1 123 ? 95.658  99.566  174.278 1.00 54.72  ? 123 ASN C O   1 
ATOM   6429  C CB  . ASN C 1 123 ? 92.999  98.905  173.030 1.00 54.72  ? 123 ASN C CB  1 
ATOM   6430  C CG  . ASN C 1 123 ? 93.118  99.151  171.536 1.00 54.72  ? 123 ASN C CG  1 
ATOM   6431  O OD1 . ASN C 1 123 ? 94.008  99.865  171.077 1.00 54.72  ? 123 ASN C OD1 1 
ATOM   6432  N ND2 . ASN C 1 123 ? 92.214  98.555  170.769 1.00 54.72  ? 123 ASN C ND2 1 
ATOM   6433  N N   . GLY C 1 124 ? 95.301  101.489 173.169 1.00 41.96  ? 124 GLY C N   1 
ATOM   6434  C CA  . GLY C 1 124 ? 96.705  101.823 173.044 1.00 41.96  ? 124 GLY C CA  1 
ATOM   6435  C C   . GLY C 1 124 ? 97.248  101.760 171.635 1.00 41.96  ? 124 GLY C C   1 
ATOM   6436  O O   . GLY C 1 124 ? 98.386  102.190 171.413 1.00 41.96  ? 124 GLY C O   1 
ATOM   6437  N N   . ASN C 1 125 ? 96.486  101.236 170.680 1.00 39.44  ? 125 ASN C N   1 
ATOM   6438  C CA  . ASN C 1 125 ? 96.937  101.220 169.297 1.00 39.44  ? 125 ASN C CA  1 
ATOM   6439  C C   . ASN C 1 125 ? 97.052  102.641 168.764 1.00 39.44  ? 125 ASN C C   1 
ATOM   6440  O O   . ASN C 1 125 ? 96.234  103.508 169.080 1.00 39.44  ? 125 ASN C O   1 
ATOM   6441  C CB  . ASN C 1 125 ? 95.978  100.408 168.429 1.00 39.44  ? 125 ASN C CB  1 
ATOM   6442  C CG  . ASN C 1 125 ? 95.851  98.972  168.889 1.00 39.44  ? 125 ASN C CG  1 
ATOM   6443  O OD1 . ASN C 1 125 ? 96.749  98.434  169.534 1.00 39.44  ? 125 ASN C OD1 1 
ATOM   6444  N ND2 . ASN C 1 125 ? 94.729  98.344  168.562 1.00 39.44  ? 125 ASN C ND2 1 
ATOM   6445  N N   . VAL C 1 126 ? 98.075  102.876 167.951 1.00 33.32  ? 126 VAL C N   1 
ATOM   6446  C CA  . VAL C 1 126 ? 98.382  104.197 167.422 1.00 33.32  ? 126 VAL C CA  1 
ATOM   6447  C C   . VAL C 1 126 ? 98.447  104.106 165.907 1.00 33.32  ? 126 VAL C C   1 
ATOM   6448  O O   . VAL C 1 126 ? 99.102  103.211 165.364 1.00 33.32  ? 126 VAL C O   1 
ATOM   6449  C CB  . VAL C 1 126 ? 99.707  104.733 167.990 1.00 33.32  ? 126 VAL C CB  1 
ATOM   6450  C CG1 . VAL C 1 126 ? 100.174 105.941 167.204 1.00 33.32  ? 126 VAL C CG1 1 
ATOM   6451  C CG2 . VAL C 1 126 ? 99.548  105.075 169.455 1.00 33.32  ? 126 VAL C CG2 1 
ATOM   6452  N N   . LEU C 1 127 ? 97.772  105.027 165.228 1.00 31.38  ? 127 LEU C N   1 
ATOM   6453  C CA  . LEU C 1 127 ? 97.855  105.145 163.780 1.00 31.38  ? 127 LEU C CA  1 
ATOM   6454  C C   . LEU C 1 127 ? 98.717  106.349 163.436 1.00 31.38  ? 127 LEU C C   1 
ATOM   6455  O O   . LEU C 1 127 ? 98.501  107.443 163.965 1.00 31.38  ? 127 LEU C O   1 
ATOM   6456  C CB  . LEU C 1 127 ? 96.469  105.289 163.153 1.00 31.38  ? 127 LEU C CB  1 
ATOM   6457  C CG  . LEU C 1 127 ? 96.381  104.975 161.660 1.00 31.38  ? 127 LEU C CG  1 
ATOM   6458  C CD1 . LEU C 1 127 ? 95.071  104.284 161.340 1.00 31.38  ? 127 LEU C CD1 1 
ATOM   6459  C CD2 . LEU C 1 127 ? 96.527  106.238 160.838 1.00 31.38  ? 127 LEU C CD2 1 
ATOM   6460  N N   . TYR C 1 128 ? 99.689  106.146 162.553 1.00 28.69  ? 128 TYR C N   1 
ATOM   6461  C CA  . TYR C 1 128 ? 100.663 107.173 162.204 1.00 28.69  ? 128 TYR C CA  1 
ATOM   6462  C C   . TYR C 1 128 ? 100.801 107.203 160.690 1.00 28.69  ? 128 TYR C C   1 
ATOM   6463  O O   . TYR C 1 128 ? 101.423 106.313 160.103 1.00 28.69  ? 128 TYR C O   1 
ATOM   6464  C CB  . TYR C 1 128 ? 102.005 106.897 162.881 1.00 28.69  ? 128 TYR C CB  1 
ATOM   6465  C CG  . TYR C 1 128 ? 103.167 107.681 162.325 1.00 28.69  ? 128 TYR C CG  1 
ATOM   6466  C CD1 . TYR C 1 128 ? 103.375 109.001 162.684 1.00 28.69  ? 128 TYR C CD1 1 
ATOM   6467  C CD2 . TYR C 1 128 ? 104.073 107.089 161.459 1.00 28.69  ? 128 TYR C CD2 1 
ATOM   6468  C CE1 . TYR C 1 128 ? 104.441 109.714 162.183 1.00 28.69  ? 128 TYR C CE1 1 
ATOM   6469  C CE2 . TYR C 1 128 ? 105.141 107.794 160.954 1.00 28.69  ? 128 TYR C CE2 1 
ATOM   6470  C CZ  . TYR C 1 128 ? 105.320 109.104 161.319 1.00 28.69  ? 128 TYR C CZ  1 
ATOM   6471  O OH  . TYR C 1 128 ? 106.386 109.808 160.816 1.00 28.69  ? 128 TYR C OH  1 
ATOM   6472  N N   . SER C 1 129 ? 100.217 108.216 160.062 1.00 30.87  ? 129 SER C N   1 
ATOM   6473  C CA  . SER C 1 129 ? 100.240 108.369 158.616 1.00 30.87  ? 129 SER C CA  1 
ATOM   6474  C C   . SER C 1 129 ? 101.100 109.564 158.241 1.00 30.87  ? 129 SER C C   1 
ATOM   6475  O O   . SER C 1 129 ? 101.116 110.573 158.950 1.00 30.87  ? 129 SER C O   1 
ATOM   6476  C CB  . SER C 1 129 ? 98.830  108.554 158.060 1.00 30.87  ? 129 SER C CB  1 
ATOM   6477  O OG  . SER C 1 129 ? 98.871  109.210 156.807 1.00 30.87  ? 129 SER C OG  1 
ATOM   6478  N N   . ILE C 1 130 ? 101.811 109.450 157.124 1.00 39.41  ? 130 ILE C N   1 
ATOM   6479  C CA  . ILE C 1 130 ? 102.732 110.495 156.696 1.00 39.41  ? 130 ILE C CA  1 
ATOM   6480  C C   . ILE C 1 130 ? 102.876 110.422 155.184 1.00 39.41  ? 130 ILE C C   1 
ATOM   6481  O O   . ILE C 1 130 ? 102.918 109.334 154.605 1.00 39.41  ? 130 ILE C O   1 
ATOM   6482  C CB  . ILE C 1 130 ? 104.091 110.355 157.414 1.00 39.41  ? 130 ILE C CB  1 
ATOM   6483  C CG1 . ILE C 1 130 ? 105.111 111.345 156.858 1.00 39.41  ? 130 ILE C CG1 1 
ATOM   6484  C CG2 . ILE C 1 130 ? 104.608 108.935 157.309 1.00 39.41  ? 130 ILE C CG2 1 
ATOM   6485  C CD1 . ILE C 1 130 ? 106.416 111.325 157.602 1.00 39.41  ? 130 ILE C CD1 1 
ATOM   6486  N N   . ARG C 1 131 ? 102.941 111.587 154.543 1.00 47.29  ? 131 ARG C N   1 
ATOM   6487  C CA  . ARG C 1 131 ? 103.036 111.686 153.093 1.00 47.29  ? 131 ARG C CA  1 
ATOM   6488  C C   . ARG C 1 131 ? 104.486 111.911 152.692 1.00 47.29  ? 131 ARG C C   1 
ATOM   6489  O O   . ARG C 1 131 ? 105.147 112.808 153.222 1.00 47.29  ? 131 ARG C O   1 
ATOM   6490  C CB  . ARG C 1 131 ? 102.159 112.824 152.571 1.00 47.29  ? 131 ARG C CB  1 
ATOM   6491  C CG  . ARG C 1 131 ? 102.562 113.350 151.206 1.00 47.29  ? 131 ARG C CG  1 
ATOM   6492  C CD  . ARG C 1 131 ? 101.783 114.606 150.849 1.00 47.29  ? 131 ARG C CD  1 
ATOM   6493  N NE  . ARG C 1 131 ? 100.814 114.369 149.787 1.00 47.29  ? 131 ARG C NE  1 
ATOM   6494  C CZ  . ARG C 1 131 ? 101.042 114.591 148.500 1.00 47.29  ? 131 ARG C CZ  1 
ATOM   6495  N NH1 . ARG C 1 131 ? 102.202 115.061 148.075 1.00 47.29  ? 131 ARG C NH1 1 
ATOM   6496  N NH2 . ARG C 1 131 ? 100.083 114.333 147.617 1.00 47.29  ? 131 ARG C NH2 1 
ATOM   6497  N N   . LEU C 1 132 ? 104.976 111.101 151.758 1.00 45.97  ? 132 LEU C N   1 
ATOM   6498  C CA  . LEU C 1 132 ? 106.356 111.177 151.306 1.00 45.97  ? 132 LEU C CA  1 
ATOM   6499  C C   . LEU C 1 132 ? 106.407 111.127 149.787 1.00 45.97  ? 132 LEU C C   1 
ATOM   6500  O O   . LEU C 1 132 ? 105.457 110.707 149.125 1.00 45.97  ? 132 LEU C O   1 
ATOM   6501  C CB  . LEU C 1 132 ? 107.204 110.040 151.880 1.00 45.97  ? 132 LEU C CB  1 
ATOM   6502  C CG  . LEU C 1 132 ? 107.474 110.036 153.381 1.00 45.97  ? 132 LEU C CG  1 
ATOM   6503  C CD1 . LEU C 1 132 ? 106.435 109.206 154.094 1.00 45.97  ? 132 LEU C CD1 1 
ATOM   6504  C CD2 . LEU C 1 132 ? 108.862 109.501 153.660 1.00 45.97  ? 132 LEU C CD2 1 
ATOM   6505  N N   . THR C 1 133 ? 107.536 111.571 149.241 1.00 30.69  ? 133 THR C N   1 
ATOM   6506  C CA  . THR C 1 133 ? 107.824 111.461 147.816 1.00 30.69  ? 133 THR C CA  1 
ATOM   6507  C C   . THR C 1 133 ? 109.168 110.769 147.665 1.00 30.69  ? 133 THR C C   1 
ATOM   6508  O O   . THR C 1 133 ? 110.172 111.243 148.203 1.00 30.69  ? 133 THR C O   1 
ATOM   6509  C CB  . THR C 1 133 ? 107.849 112.832 147.141 1.00 30.69  ? 133 THR C CB  1 
ATOM   6510  O OG1 . THR C 1 133 ? 106.510 113.317 146.999 1.00 30.69  ? 133 THR C OG1 1 
ATOM   6511  C CG2 . THR C 1 133 ? 108.489 112.733 145.771 1.00 30.69  ? 133 THR C CG2 1 
ATOM   6512  N N   . LEU C 1 134 ? 109.189 109.658 146.937 1.00 28.58  ? 134 LEU C N   1 
ATOM   6513  C CA  . LEU C 1 134 ? 110.363 108.802 146.876 1.00 28.58  ? 134 LEU C CA  1 
ATOM   6514  C C   . LEU C 1 134 ? 110.722 108.526 145.427 1.00 28.58  ? 134 LEU C C   1 
ATOM   6515  O O   . LEU C 1 134 ? 109.857 108.137 144.639 1.00 28.58  ? 134 LEU C O   1 
ATOM   6516  C CB  . LEU C 1 134 ? 110.122 107.477 147.598 1.00 28.58  ? 134 LEU C CB  1 
ATOM   6517  C CG  . LEU C 1 134 ? 109.712 107.478 149.067 1.00 28.58  ? 134 LEU C CG  1 
ATOM   6518  C CD1 . LEU C 1 134 ? 108.250 107.825 149.248 1.00 28.58  ? 134 LEU C CD1 1 
ATOM   6519  C CD2 . LEU C 1 134 ? 109.996 106.125 149.645 1.00 28.58  ? 134 LEU C CD2 1 
ATOM   6520  N N   . THR C 1 135 ? 111.995 108.717 145.081 1.00 29.54  ? 135 THR C N   1 
ATOM   6521  C CA  . THR C 1 135 ? 112.506 108.333 143.768 1.00 29.54  ? 135 THR C CA  1 
ATOM   6522  C C   . THR C 1 135 ? 113.245 107.007 143.921 1.00 29.54  ? 135 THR C C   1 
ATOM   6523  O O   . THR C 1 135 ? 114.472 106.941 143.925 1.00 29.54  ? 135 THR C O   1 
ATOM   6524  C CB  . THR C 1 135 ? 113.406 109.418 143.195 1.00 29.54  ? 135 THR C CB  1 
ATOM   6525  O OG1 . THR C 1 135 ? 114.667 109.396 143.871 1.00 29.54  ? 135 THR C OG1 1 
ATOM   6526  C CG2 . THR C 1 135 ? 112.768 110.780 143.378 1.00 29.54  ? 135 THR C CG2 1 
ATOM   6527  N N   . LEU C 1 136 ? 112.471 105.935 144.049 1.00 34.61  ? 136 LEU C N   1 
ATOM   6528  C CA  . LEU C 1 136 ? 113.046 104.607 144.195 1.00 34.61  ? 136 LEU C CA  1 
ATOM   6529  C C   . LEU C 1 136 ? 113.716 104.165 142.900 1.00 34.61  ? 136 LEU C C   1 
ATOM   6530  O O   . LEU C 1 136 ? 113.371 104.620 141.808 1.00 34.61  ? 136 LEU C O   1 
ATOM   6531  C CB  . LEU C 1 136 ? 111.971 103.601 144.589 1.00 34.61  ? 136 LEU C CB  1 
ATOM   6532  C CG  . LEU C 1 136 ? 110.947 104.101 145.602 1.00 34.61  ? 136 LEU C CG  1 
ATOM   6533  C CD1 . LEU C 1 136 ? 109.750 103.175 145.640 1.00 34.61  ? 136 LEU C CD1 1 
ATOM   6534  C CD2 . LEU C 1 136 ? 111.583 104.204 146.969 1.00 34.61  ? 136 LEU C CD2 1 
ATOM   6535  N N   . SER C 1 137 ? 114.683 103.263 143.032 1.00 43.36  ? 137 SER C N   1 
ATOM   6536  C CA  . SER C 1 137 ? 115.440 102.744 141.902 1.00 43.36  ? 137 SER C CA  1 
ATOM   6537  C C   . SER C 1 137 ? 115.137 101.264 141.722 1.00 43.36  ? 137 SER C C   1 
ATOM   6538  O O   . SER C 1 137 ? 115.187 100.495 142.686 1.00 43.36  ? 137 SER C O   1 
ATOM   6539  C CB  . SER C 1 137 ? 116.941 102.948 142.106 1.00 43.36  ? 137 SER C CB  1 
ATOM   6540  O OG  . SER C 1 137 ? 117.480 101.931 142.933 1.00 43.36  ? 137 SER C OG  1 
ATOM   6541  N N   . CYS C 1 138 ? 114.824 100.871 140.489 1.00 51.56  ? 138 CYS C N   1 
ATOM   6542  C CA  . CYS C 1 138 ? 114.571 99.474  140.157 1.00 51.56  ? 138 CYS C CA  1 
ATOM   6543  C C   . CYS C 1 138 ? 115.425 99.108  138.952 1.00 51.56  ? 138 CYS C C   1 
ATOM   6544  O O   . CYS C 1 138 ? 115.285 99.738  137.884 1.00 51.56  ? 138 CYS C O   1 
ATOM   6545  C CB  . CYS C 1 138 ? 113.089 99.224  139.869 1.00 51.56  ? 138 CYS C CB  1 
ATOM   6546  S SG  . CYS C 1 138 ? 112.294 100.447 138.799 1.00 51.56  ? 138 CYS C SG  1 
ATOM   6547  N N   . PRO C 1 139 ? 116.318 98.126  139.065 1.00 56.81  ? 139 PRO C N   1 
ATOM   6548  C CA  . PRO C 1 139 ? 117.083 97.692  137.891 1.00 56.81  ? 139 PRO C CA  1 
ATOM   6549  C C   . PRO C 1 139 ? 116.155 97.154  136.813 1.00 56.81  ? 139 PRO C C   1 
ATOM   6550  O O   . PRO C 1 139 ? 115.144 96.510  137.101 1.00 56.81  ? 139 PRO C O   1 
ATOM   6551  C CB  . PRO C 1 139 ? 118.004 96.602  138.448 1.00 56.81  ? 139 PRO C CB  1 
ATOM   6552  C CG  . PRO C 1 139 ? 117.333 96.136  139.695 1.00 56.81  ? 139 PRO C CG  1 
ATOM   6553  C CD  . PRO C 1 139 ? 116.641 97.335  140.262 1.00 56.81  ? 139 PRO C CD  1 
ATOM   6554  N N   . MET C 1 140 ? 116.510 97.422  135.561 1.00 60.58  ? 140 MET C N   1 
ATOM   6555  C CA  . MET C 1 140 ? 115.646 97.131  134.430 1.00 60.58  ? 140 MET C CA  1 
ATOM   6556  C C   . MET C 1 140 ? 116.328 96.169  133.468 1.00 60.58  ? 140 MET C C   1 
ATOM   6557  O O   . MET C 1 140 ? 117.551 96.191  133.302 1.00 60.58  ? 140 MET C O   1 
ATOM   6558  C CB  . MET C 1 140 ? 115.261 98.416  133.695 1.00 60.58  ? 140 MET C CB  1 
ATOM   6559  C CG  . MET C 1 140 ? 114.899 99.562  134.619 1.00 60.58  ? 140 MET C CG  1 
ATOM   6560  S SD  . MET C 1 140 ? 113.383 100.400 134.128 1.00 60.58  ? 140 MET C SD  1 
ATOM   6561  C CE  . MET C 1 140 ? 113.772 100.822 132.435 1.00 60.58  ? 140 MET C CE  1 
ATOM   6562  N N   . ASP C 1 141 ? 115.519 95.324  132.836 1.00 63.41  ? 141 ASP C N   1 
ATOM   6563  C CA  . ASP C 1 141 ? 115.979 94.373  131.835 1.00 63.41  ? 141 ASP C CA  1 
ATOM   6564  C C   . ASP C 1 141 ? 115.389 94.756  130.486 1.00 63.41  ? 141 ASP C C   1 
ATOM   6565  O O   . ASP C 1 141 ? 114.174 94.947  130.369 1.00 63.41  ? 141 ASP C O   1 
ATOM   6566  C CB  . ASP C 1 141 ? 115.573 92.945  132.209 1.00 63.41  ? 141 ASP C CB  1 
ATOM   6567  C CG  . ASP C 1 141 ? 116.425 91.894  131.524 1.00 63.41  ? 141 ASP C CG  1 
ATOM   6568  O OD1 . ASP C 1 141 ? 116.841 92.120  130.369 1.00 63.41  ? 141 ASP C OD1 1 
ATOM   6569  O OD2 . ASP C 1 141 ? 116.677 90.839  132.142 1.00 63.41  ? 141 ASP C OD2 1 
ATOM   6570  N N   . LEU C 1 142 ? 116.244 94.864  129.475 1.00 63.48  ? 142 LEU C N   1 
ATOM   6571  C CA  . LEU C 1 142 ? 115.839 95.300  128.145 1.00 63.48  ? 142 LEU C CA  1 
ATOM   6572  C C   . LEU C 1 142 ? 116.174 94.251  127.092 1.00 63.48  ? 142 LEU C C   1 
ATOM   6573  O O   . LEU C 1 142 ? 116.552 94.575  125.964 1.00 63.48  ? 142 LEU C O   1 
ATOM   6574  C CB  . LEU C 1 142 ? 116.485 96.638  127.796 1.00 63.48  ? 142 LEU C CB  1 
ATOM   6575  C CG  . LEU C 1 142 ? 116.289 97.756  128.818 1.00 63.48  ? 142 LEU C CG  1 
ATOM   6576  C CD1 . LEU C 1 142 ? 117.004 99.017  128.377 1.00 63.48  ? 142 LEU C CD1 1 
ATOM   6577  C CD2 . LEU C 1 142 ? 114.813 98.026  129.023 1.00 63.48  ? 142 LEU C CD2 1 
ATOM   6578  N N   . LYS C 1 143 ? 116.039 92.971  127.450 1.00 60.37  ? 143 LYS C N   1 
ATOM   6579  C CA  . LYS C 1 143 ? 116.256 91.908  126.474 1.00 60.37  ? 143 LYS C CA  1 
ATOM   6580  C C   . LYS C 1 143 ? 115.240 91.979  125.344 1.00 60.37  ? 143 LYS C C   1 
ATOM   6581  O O   . LYS C 1 143 ? 115.534 91.568  124.217 1.00 60.37  ? 143 LYS C O   1 
ATOM   6582  C CB  . LYS C 1 143 ? 116.197 90.543  127.160 1.00 60.37  ? 143 LYS C CB  1 
ATOM   6583  N N   . ASN C 1 144 ? 114.041 92.490  125.628 1.00 56.88  ? 144 ASN C N   1 
ATOM   6584  C CA  . ASN C 1 144 ? 113.008 92.742  124.620 1.00 56.88  ? 144 ASN C CA  1 
ATOM   6585  C C   . ASN C 1 144 ? 112.371 94.077  124.996 1.00 56.88  ? 144 ASN C C   1 
ATOM   6586  O O   . ASN C 1 144 ? 111.424 94.125  125.784 1.00 56.88  ? 144 ASN C O   1 
ATOM   6587  C CB  . ASN C 1 144 ? 111.988 91.611  124.563 1.00 56.88  ? 144 ASN C CB  1 
ATOM   6588  C CG  . ASN C 1 144 ? 111.751 90.968  125.915 1.00 56.88  ? 144 ASN C CG  1 
ATOM   6589  O OD1 . ASN C 1 144 ? 111.721 91.643  126.941 1.00 56.88  ? 144 ASN C OD1 1 
ATOM   6590  N ND2 . ASN C 1 144 ? 111.581 89.652  125.919 1.00 56.88  ? 144 ASN C ND2 1 
ATOM   6591  N N   . PHE C 1 145 ? 112.896 95.164  124.415 1.00 56.74  ? 145 PHE C N   1 
ATOM   6592  C CA  . PHE C 1 145 ? 112.592 96.492  124.951 1.00 56.74  ? 145 PHE C CA  1 
ATOM   6593  C C   . PHE C 1 145 ? 111.134 96.889  124.759 1.00 56.74  ? 145 PHE C C   1 
ATOM   6594  O O   . PHE C 1 145 ? 110.433 97.102  125.764 1.00 56.74  ? 145 PHE C O   1 
ATOM   6595  C CB  . PHE C 1 145 ? 113.553 97.527  124.363 1.00 56.74  ? 145 PHE C CB  1 
ATOM   6596  C CG  . PHE C 1 145 ? 113.062 98.934  124.490 1.00 56.74  ? 145 PHE C CG  1 
ATOM   6597  C CD1 . PHE C 1 145 ? 113.152 99.600  125.697 1.00 56.74  ? 145 PHE C CD1 1 
ATOM   6598  C CD2 . PHE C 1 145 ? 112.511 99.592  123.407 1.00 56.74  ? 145 PHE C CD2 1 
ATOM   6599  C CE1 . PHE C 1 145 ? 112.701 100.893 125.823 1.00 56.74  ? 145 PHE C CE1 1 
ATOM   6600  C CE2 . PHE C 1 145 ? 112.056 100.884 123.529 1.00 56.74  ? 145 PHE C CE2 1 
ATOM   6601  C CZ  . PHE C 1 145 ? 112.151 101.535 124.739 1.00 56.74  ? 145 PHE C CZ  1 
ATOM   6602  N N   . PRO C 1 146 ? 110.612 97.026  123.535 1.00 56.47  ? 146 PRO C N   1 
ATOM   6603  C CA  . PRO C 1 146 ? 109.270 97.616  123.394 1.00 56.47  ? 146 PRO C CA  1 
ATOM   6604  C C   . PRO C 1 146 ? 108.163 96.784  124.016 1.00 56.47  ? 146 PRO C C   1 
ATOM   6605  O O   . PRO C 1 146 ? 107.110 97.334  124.358 1.00 56.47  ? 146 PRO C O   1 
ATOM   6606  C CB  . PRO C 1 146 ? 109.097 97.733  121.872 1.00 56.47  ? 146 PRO C CB  1 
ATOM   6607  C CG  . PRO C 1 146 ? 110.471 97.586  121.309 1.00 56.47  ? 146 PRO C CG  1 
ATOM   6608  C CD  . PRO C 1 146 ? 111.145 96.626  122.224 1.00 56.47  ? 146 PRO C CD  1 
ATOM   6609  N N   . MET C 1 147 ? 108.368 95.484  124.190 1.00 55.59  ? 147 MET C N   1 
ATOM   6610  C CA  . MET C 1 147 ? 107.344 94.581  124.700 1.00 55.59  ? 147 MET C CA  1 
ATOM   6611  C C   . MET C 1 147 ? 107.770 93.951  126.021 1.00 55.59  ? 147 MET C C   1 
ATOM   6612  O O   . MET C 1 147 ? 107.538 92.766  126.267 1.00 55.59  ? 147 MET C O   1 
ATOM   6613  C CB  . MET C 1 147 ? 107.016 93.500  123.674 1.00 55.59  ? 147 MET C CB  1 
ATOM   6614  C CG  . MET C 1 147 ? 106.755 94.028  122.274 1.00 55.59  ? 147 MET C CG  1 
ATOM   6615  S SD  . MET C 1 147 ? 108.257 94.255  121.307 1.00 55.59  ? 147 MET C SD  1 
ATOM   6616  C CE  . MET C 1 147 ? 108.613 92.568  120.832 1.00 55.59  ? 147 MET C CE  1 
ATOM   6617  N N   . ASP C 1 148 ? 108.396 94.738  126.891 1.00 53.27  ? 148 ASP C N   1 
ATOM   6618  C CA  . ASP C 1 148 ? 108.920 94.225  128.148 1.00 53.27  ? 148 ASP C CA  1 
ATOM   6619  C C   . ASP C 1 148 ? 107.875 94.309  129.251 1.00 53.27  ? 148 ASP C C   1 
ATOM   6620  O O   . ASP C 1 148 ? 107.067 95.240  129.291 1.00 53.27  ? 148 ASP C O   1 
ATOM   6621  C CB  . ASP C 1 148 ? 110.175 94.992  128.567 1.00 53.27  ? 148 ASP C CB  1 
ATOM   6622  C CG  . ASP C 1 148 ? 109.947 96.486  128.651 1.00 53.27  ? 148 ASP C CG  1 
ATOM   6623  O OD1 . ASP C 1 148 ? 108.914 96.965  128.141 1.00 53.27  ? 148 ASP C OD1 1 
ATOM   6624  O OD2 . ASP C 1 148 ? 110.806 97.187  129.226 1.00 53.27  ? 148 ASP C OD2 1 
ATOM   6625  N N   . VAL C 1 149 ? 107.895 93.325  130.141 1.00 52.39  ? 149 VAL C N   1 
ATOM   6626  C CA  . VAL C 1 149 ? 107.109 93.341  131.367 1.00 52.39  ? 149 VAL C CA  1 
ATOM   6627  C C   . VAL C 1 149 ? 108.096 93.494  132.513 1.00 52.39  ? 149 VAL C C   1 
ATOM   6628  O O   . VAL C 1 149 ? 108.898 92.590  132.778 1.00 52.39  ? 149 VAL C O   1 
ATOM   6629  C CB  . VAL C 1 149 ? 106.261 92.073  131.524 1.00 52.39  ? 149 VAL C CB  1 
ATOM   6630  C CG1 . VAL C 1 149 ? 105.426 92.149  132.791 1.00 52.39  ? 149 VAL C CG1 1 
ATOM   6631  C CG2 . VAL C 1 149 ? 105.376 91.877  130.307 1.00 52.39  ? 149 VAL C CG2 1 
ATOM   6632  N N   . GLN C 1 150 ? 108.042 94.630  133.198 1.00 48.08  ? 150 GLN C N   1 
ATOM   6633  C CA  . GLN C 1 150 ? 109.036 94.981  134.198 1.00 48.08  ? 150 GLN C CA  1 
ATOM   6634  C C   . GLN C 1 150 ? 108.450 94.872  135.598 1.00 48.08  ? 150 GLN C C   1 
ATOM   6635  O O   . GLN C 1 150 ? 107.235 94.939  135.799 1.00 48.08  ? 150 GLN C O   1 
ATOM   6636  C CB  . GLN C 1 150 ? 109.567 96.395  133.959 1.00 48.08  ? 150 GLN C CB  1 
ATOM   6637  C CG  . GLN C 1 150 ? 110.604 96.466  132.863 1.00 48.08  ? 150 GLN C CG  1 
ATOM   6638  C CD  . GLN C 1 150 ? 111.294 97.805  132.807 1.00 48.08  ? 150 GLN C CD  1 
ATOM   6639  O OE1 . GLN C 1 150 ? 112.432 97.907  132.358 1.00 48.08  ? 150 GLN C OE1 1 
ATOM   6640  N NE2 . GLN C 1 150 ? 110.611 98.843  133.270 1.00 48.08  ? 150 GLN C NE2 1 
ATOM   6641  N N   . THR C 1 151 ? 109.341 94.701  136.573 1.00 42.08  ? 151 THR C N   1 
ATOM   6642  C CA  . THR C 1 151 ? 108.966 94.511  137.973 1.00 42.08  ? 151 THR C CA  1 
ATOM   6643  C C   . THR C 1 151 ? 109.830 95.435  138.823 1.00 42.08  ? 151 THR C C   1 
ATOM   6644  O O   . THR C 1 151 ? 110.937 95.068  139.224 1.00 42.08  ? 151 THR C O   1 
ATOM   6645  C CB  . THR C 1 151 ? 109.128 93.053  138.389 1.00 42.08  ? 151 THR C CB  1 
ATOM   6646  O OG1 . THR C 1 151 ? 108.353 92.218  137.520 1.00 42.08  ? 151 THR C OG1 1 
ATOM   6647  C CG2 . THR C 1 151 ? 108.660 92.852  139.820 1.00 42.08  ? 151 THR C CG2 1 
ATOM   6648  N N   . CYS C 1 152 ? 109.327 96.634  139.094 1.00 41.58  ? 152 CYS C N   1 
ATOM   6649  C CA  . CYS C 1 152 ? 110.001 97.548  140.000 1.00 41.58  ? 152 CYS C CA  1 
ATOM   6650  C C   . CYS C 1 152 ? 109.566 97.266  141.432 1.00 41.58  ? 152 CYS C C   1 
ATOM   6651  O O   . CYS C 1 152 ? 108.453 96.797  141.683 1.00 41.58  ? 152 CYS C O   1 
ATOM   6652  C CB  . CYS C 1 152 ? 109.721 99.003  139.624 1.00 41.58  ? 152 CYS C CB  1 
ATOM   6653  S SG  . CYS C 1 152 ? 110.598 99.543  138.131 1.00 41.58  ? 152 CYS C SG  1 
ATOM   6654  N N   . ILE C 1 153 ? 110.459 97.557  142.373 1.00 34.66  ? 153 ILE C N   1 
ATOM   6655  C CA  . ILE C 1 153 ? 110.373 97.019  143.722 1.00 34.66  ? 153 ILE C CA  1 
ATOM   6656  C C   . ILE C 1 153 ? 110.467 98.145  144.742 1.00 34.66  ? 153 ILE C C   1 
ATOM   6657  O O   . ILE C 1 153 ? 111.051 99.200  144.482 1.00 34.66  ? 153 ILE C O   1 
ATOM   6658  C CB  . ILE C 1 153 ? 111.485 95.969  143.946 1.00 34.66  ? 153 ILE C CB  1 
ATOM   6659  C CG1 . ILE C 1 153 ? 111.221 95.124  145.189 1.00 34.66  ? 153 ILE C CG1 1 
ATOM   6660  C CG2 . ILE C 1 153 ? 112.849 96.637  144.022 1.00 34.66  ? 153 ILE C CG2 1 
ATOM   6661  C CD1 . ILE C 1 153 ? 112.355 94.180  145.506 1.00 34.66  ? 153 ILE C CD1 1 
ATOM   6662  N N   . MET C 1 154 ? 109.866 97.916  145.908 1.00 35.63  ? 154 MET C N   1 
ATOM   6663  C CA  . MET C 1 154 ? 109.965 98.808  147.054 1.00 35.63  ? 154 MET C CA  1 
ATOM   6664  C C   . MET C 1 154 ? 110.193 97.974  148.305 1.00 35.63  ? 154 MET C C   1 
ATOM   6665  O O   . MET C 1 154 ? 109.526 96.956  148.506 1.00 35.63  ? 154 MET C O   1 
ATOM   6666  C CB  . MET C 1 154 ? 108.701 99.656  147.219 1.00 35.63  ? 154 MET C CB  1 
ATOM   6667  C CG  . MET C 1 154 ? 108.705 100.532 148.459 1.00 35.63  ? 154 MET C CG  1 
ATOM   6668  S SD  . MET C 1 154 ? 107.493 101.867 148.421 1.00 35.63  ? 154 MET C SD  1 
ATOM   6669  C CE  . MET C 1 154 ? 106.698 101.584 146.843 1.00 35.63  ? 154 MET C CE  1 
ATOM   6670  N N   . GLN C 1 155 ? 111.131 98.403  149.148 1.00 33.50  ? 155 GLN C N   1 
ATOM   6671  C CA  . GLN C 1 155 ? 111.510 97.647  150.338 1.00 33.50  ? 155 GLN C CA  1 
ATOM   6672  C C   . GLN C 1 155 ? 111.417 98.544  151.564 1.00 33.50  ? 155 GLN C C   1 
ATOM   6673  O O   . GLN C 1 155 ? 112.272 99.411  151.767 1.00 33.50  ? 155 GLN C O   1 
ATOM   6674  C CB  . GLN C 1 155 ? 112.920 97.076  150.202 1.00 33.50  ? 155 GLN C CB  1 
ATOM   6675  C CG  . GLN C 1 155 ? 113.131 96.213  148.975 1.00 33.50  ? 155 GLN C CG  1 
ATOM   6676  C CD  . GLN C 1 155 ? 114.456 95.479  149.004 1.00 33.50  ? 155 GLN C CD  1 
ATOM   6677  O OE1 . GLN C 1 155 ? 114.948 95.108  150.069 1.00 33.50  ? 155 GLN C OE1 1 
ATOM   6678  N NE2 . GLN C 1 155 ? 115.043 95.268  147.833 1.00 33.50  ? 155 GLN C NE2 1 
ATOM   6679  N N   . LEU C 1 156 ? 110.392 98.329  152.383 1.00 32.00  ? 156 LEU C N   1 
ATOM   6680  C CA  . LEU C 1 156 ? 110.287 98.976  153.684 1.00 32.00  ? 156 LEU C CA  1 
ATOM   6681  C C   . LEU C 1 156 ? 111.013 98.124  154.715 1.00 32.00  ? 156 LEU C C   1 
ATOM   6682  O O   . LEU C 1 156 ? 110.731 96.930  154.844 1.00 32.00  ? 156 LEU C O   1 
ATOM   6683  C CB  . LEU C 1 156 ? 108.824 99.152  154.090 1.00 32.00  ? 156 LEU C CB  1 
ATOM   6684  C CG  . LEU C 1 156 ? 107.985 100.175 153.330 1.00 32.00  ? 156 LEU C CG  1 
ATOM   6685  C CD1 . LEU C 1 156 ? 107.308 99.530  152.138 1.00 32.00  ? 156 LEU C CD1 1 
ATOM   6686  C CD2 . LEU C 1 156 ? 106.956 100.792 154.253 1.00 32.00  ? 156 LEU C CD2 1 
ATOM   6687  N N   . GLU C 1 157 ? 111.943 98.730  155.447 1.00 35.63  ? 157 GLU C N   1 
ATOM   6688  C CA  . GLU C 1 157 ? 112.716 97.966  156.414 1.00 35.63  ? 157 GLU C CA  1 
ATOM   6689  C C   . GLU C 1 157 ? 113.204 98.880  157.526 1.00 35.63  ? 157 GLU C C   1 
ATOM   6690  O O   . GLU C 1 157 ? 113.293 100.099 157.364 1.00 35.63  ? 157 GLU C O   1 
ATOM   6691  C CB  . GLU C 1 157 ? 113.893 97.253  155.742 1.00 35.63  ? 157 GLU C CB  1 
ATOM   6692  C CG  . GLU C 1 157 ? 115.235 97.928  155.926 1.00 35.63  ? 157 GLU C CG  1 
ATOM   6693  C CD  . GLU C 1 157 ? 116.309 97.317  155.054 1.00 35.63  ? 157 GLU C CD  1 
ATOM   6694  O OE1 . GLU C 1 157 ? 116.061 96.240  154.477 1.00 35.63  ? 157 GLU C OE1 1 
ATOM   6695  O OE2 . GLU C 1 157 ? 117.403 97.907  154.947 1.00 35.63  ? 157 GLU C OE2 1 
ATOM   6696  N N   . SER C 1 158 ? 113.518 98.270  158.664 1.00 34.57  ? 158 SER C N   1 
ATOM   6697  C CA  . SER C 1 158 ? 114.035 98.987  159.817 1.00 34.57  ? 158 SER C CA  1 
ATOM   6698  C C   . SER C 1 158 ? 115.550 99.107  159.738 1.00 34.57  ? 158 SER C C   1 
ATOM   6699  O O   . SER C 1 158 ? 116.221 98.363  159.021 1.00 34.57  ? 158 SER C O   1 
ATOM   6700  C CB  . SER C 1 158 ? 113.640 98.282  161.112 1.00 34.57  ? 158 SER C CB  1 
ATOM   6701  O OG  . SER C 1 158 ? 114.437 98.736  162.190 1.00 34.57  ? 158 SER C OG  1 
ATOM   6702  N N   . PHE C 1 159 ? 116.087 100.065 160.492 1.00 36.32  ? 159 PHE C N   1 
ATOM   6703  C CA  . PHE C 1 159 ? 117.525 100.301 160.488 1.00 36.32  ? 159 PHE C CA  1 
ATOM   6704  C C   . PHE C 1 159 ? 118.093 100.345 161.899 1.00 36.32  ? 159 PHE C C   1 
ATOM   6705  O O   . PHE C 1 159 ? 119.244 99.958  162.122 1.00 36.32  ? 159 PHE C O   1 
ATOM   6706  C CB  . PHE C 1 159 ? 117.844 101.605 159.759 1.00 36.32  ? 159 PHE C CB  1 
ATOM   6707  C CG  . PHE C 1 159 ? 119.310 101.855 159.581 1.00 36.32  ? 159 PHE C CG  1 
ATOM   6708  C CD1 . PHE C 1 159 ? 120.157 100.833 159.201 1.00 36.32  ? 159 PHE C CD1 1 
ATOM   6709  C CD2 . PHE C 1 159 ? 119.837 103.116 159.781 1.00 36.32  ? 159 PHE C CD2 1 
ATOM   6710  C CE1 . PHE C 1 159 ? 121.504 101.062 159.033 1.00 36.32  ? 159 PHE C CE1 1 
ATOM   6711  C CE2 . PHE C 1 159 ? 121.182 103.350 159.613 1.00 36.32  ? 159 PHE C CE2 1 
ATOM   6712  C CZ  . PHE C 1 159 ? 122.016 102.322 159.239 1.00 36.32  ? 159 PHE C CZ  1 
ATOM   6713  N N   . GLY C 1 160 ? 117.298 100.809 162.857 1.00 39.50  ? 160 GLY C N   1 
ATOM   6714  C CA  . GLY C 1 160 ? 117.755 100.999 164.216 1.00 39.50  ? 160 GLY C CA  1 
ATOM   6715  C C   . GLY C 1 160 ? 117.322 99.953  165.218 1.00 39.50  ? 160 GLY C C   1 
ATOM   6716  O O   . GLY C 1 160 ? 117.492 100.170 166.423 1.00 39.50  ? 160 GLY C O   1 
ATOM   6717  N N   . TYR C 1 161 ? 116.768 98.828  164.774 1.00 37.87  ? 161 TYR C N   1 
ATOM   6718  C CA  . TYR C 1 161 ? 116.288 97.817  165.705 1.00 37.87  ? 161 TYR C CA  1 
ATOM   6719  C C   . TYR C 1 161 ? 116.488 96.434  165.108 1.00 37.87  ? 161 TYR C C   1 
ATOM   6720  O O   . TYR C 1 161 ? 116.117 96.191  163.957 1.00 37.87  ? 161 TYR C O   1 
ATOM   6721  C CB  . TYR C 1 161 ? 114.810 98.031  166.041 1.00 37.87  ? 161 TYR C CB  1 
ATOM   6722  C CG  . TYR C 1 161 ? 114.520 99.292  166.822 1.00 37.87  ? 161 TYR C CG  1 
ATOM   6723  C CD1 . TYR C 1 161 ? 114.720 99.344  168.193 1.00 37.87  ? 161 TYR C CD1 1 
ATOM   6724  C CD2 . TYR C 1 161 ? 114.033 100.425 166.188 1.00 37.87  ? 161 TYR C CD2 1 
ATOM   6725  C CE1 . TYR C 1 161 ? 114.449 100.490 168.909 1.00 37.87  ? 161 TYR C CE1 1 
ATOM   6726  C CE2 . TYR C 1 161 ? 113.760 101.575 166.896 1.00 37.87  ? 161 TYR C CE2 1 
ATOM   6727  C CZ  . TYR C 1 161 ? 113.970 101.603 168.256 1.00 37.87  ? 161 TYR C CZ  1 
ATOM   6728  O OH  . TYR C 1 161 ? 113.699 102.749 168.965 1.00 37.87  ? 161 TYR C OH  1 
ATOM   6729  N N   . THR C 1 162 ? 117.066 95.537  165.898 1.00 38.48  ? 162 THR C N   1 
ATOM   6730  C CA  . THR C 1 162 ? 117.173 94.141  165.511 1.00 38.48  ? 162 THR C CA  1 
ATOM   6731  C C   . THR C 1 162 ? 115.781 93.517  165.464 1.00 38.48  ? 162 THR C C   1 
ATOM   6732  O O   . THR C 1 162 ? 114.846 93.993  166.111 1.00 38.48  ? 162 THR C O   1 
ATOM   6733  C CB  . THR C 1 162 ? 118.072 93.394  166.503 1.00 38.48  ? 162 THR C CB  1 
ATOM   6734  O OG1 . THR C 1 162 ? 119.331 94.069  166.603 1.00 38.48  ? 162 THR C OG1 1 
ATOM   6735  C CG2 . THR C 1 162 ? 118.335 91.965  166.056 1.00 38.48  ? 162 THR C CG2 1 
ATOM   6736  N N   . MET C 1 163 ? 115.643 92.448  164.675 1.00 39.76  ? 163 MET C N   1 
ATOM   6737  C CA  . MET C 1 163 ? 114.375 91.728  164.605 1.00 39.76  ? 163 MET C CA  1 
ATOM   6738  C C   . MET C 1 163 ? 113.915 91.237  165.971 1.00 39.76  ? 163 MET C C   1 
ATOM   6739  O O   . MET C 1 163 ? 112.748 90.865  166.128 1.00 39.76  ? 163 MET C O   1 
ATOM   6740  C CB  . MET C 1 163 ? 114.498 90.546  163.643 1.00 39.76  ? 163 MET C CB  1 
ATOM   6741  C CG  . MET C 1 163 ? 113.175 90.043  163.099 1.00 39.76  ? 163 MET C CG  1 
ATOM   6742  S SD  . MET C 1 163 ? 113.364 89.203  161.518 1.00 39.76  ? 163 MET C SD  1 
ATOM   6743  C CE  . MET C 1 163 ? 111.679 89.229  160.918 1.00 39.76  ? 163 MET C CE  1 
ATOM   6744  N N   . ASN C 1 164 ? 114.807 91.224  166.961 1.00 43.32  ? 164 ASN C N   1 
ATOM   6745  C CA  . ASN C 1 164 ? 114.434 90.929  168.337 1.00 43.32  ? 164 ASN C CA  1 
ATOM   6746  C C   . ASN C 1 164 ? 113.594 92.031  168.970 1.00 43.32  ? 164 ASN C C   1 
ATOM   6747  O O   . ASN C 1 164 ? 113.021 91.809  170.041 1.00 43.32  ? 164 ASN C O   1 
ATOM   6748  C CB  . ASN C 1 164 ? 115.697 90.693  169.168 1.00 43.32  ? 164 ASN C CB  1 
ATOM   6749  C CG  . ASN C 1 164 ? 115.397 90.148  170.547 1.00 43.32  ? 164 ASN C CG  1 
ATOM   6750  O OD1 . ASN C 1 164 ? 114.428 89.415  170.739 1.00 43.32  ? 164 ASN C OD1 1 
ATOM   6751  N ND2 . ASN C 1 164 ? 116.227 90.507  171.518 1.00 43.32  ? 164 ASN C ND2 1 
ATOM   6752  N N   . ASP C 1 165 ? 113.509 93.206  168.348 1.00 42.29  ? 165 ASP C N   1 
ATOM   6753  C CA  . ASP C 1 165 ? 112.779 94.334  168.915 1.00 42.29  ? 165 ASP C CA  1 
ATOM   6754  C C   . ASP C 1 165 ? 111.629 94.801  168.038 1.00 42.29  ? 165 ASP C C   1 
ATOM   6755  O O   . ASP C 1 165 ? 110.523 95.022  168.543 1.00 42.29  ? 165 ASP C O   1 
ATOM   6756  C CB  . ASP C 1 165 ? 113.741 95.504  169.176 1.00 42.29  ? 165 ASP C CB  1 
ATOM   6757  C CG  . ASP C 1 165 ? 114.739 95.201  170.271 1.00 42.29  ? 165 ASP C CG  1 
ATOM   6758  O OD1 . ASP C 1 165 ? 114.583 94.163  170.945 1.00 42.29  ? 165 ASP C OD1 1 
ATOM   6759  O OD2 . ASP C 1 165 ? 115.679 96.000  170.460 1.00 42.29  ? 165 ASP C OD2 1 
ATOM   6760  N N   . LEU C 1 166 ? 111.855 94.967  166.738 1.00 36.84  ? 166 LEU C N   1 
ATOM   6761  C CA  . LEU C 1 166 ? 110.856 95.505  165.825 1.00 36.84  ? 166 LEU C CA  1 
ATOM   6762  C C   . LEU C 1 166 ? 110.599 94.507  164.707 1.00 36.84  ? 166 LEU C C   1 
ATOM   6763  O O   . LEU C 1 166 ? 111.544 93.993  164.102 1.00 36.84  ? 166 LEU C O   1 
ATOM   6764  C CB  . LEU C 1 166 ? 111.319 96.841  165.243 1.00 36.84  ? 166 LEU C CB  1 
ATOM   6765  C CG  . LEU C 1 166 ? 110.264 97.683  164.533 1.00 36.84  ? 166 LEU C CG  1 
ATOM   6766  C CD1 . LEU C 1 166 ? 109.286 98.245  165.539 1.00 36.84  ? 166 LEU C CD1 1 
ATOM   6767  C CD2 . LEU C 1 166 ? 110.920 98.797  163.743 1.00 36.84  ? 166 LEU C CD2 1 
ATOM   6768  N N   . ILE C 1 167 ? 109.325 94.235  164.434 1.00 36.17  ? 167 ILE C N   1 
ATOM   6769  C CA  . ILE C 1 167 ? 108.924 93.323  163.370 1.00 36.17  ? 167 ILE C CA  1 
ATOM   6770  C C   . ILE C 1 167 ? 107.929 94.038  162.469 1.00 36.17  ? 167 ILE C C   1 
ATOM   6771  O O   . ILE C 1 167 ? 106.921 94.567  162.949 1.00 36.17  ? 167 ILE C O   1 
ATOM   6772  C CB  . ILE C 1 167 ? 108.304 92.027  163.925 1.00 36.17  ? 167 ILE C CB  1 
ATOM   6773  C CG1 . ILE C 1 167 ? 109.280 91.324  164.865 1.00 36.17  ? 167 ILE C CG1 1 
ATOM   6774  C CG2 . ILE C 1 167 ? 107.912 91.102  162.790 1.00 36.17  ? 167 ILE C CG2 1 
ATOM   6775  C CD1 . ILE C 1 167 ? 108.752 90.022  165.424 1.00 36.17  ? 167 ILE C CD1 1 
ATOM   6776  N N   . PHE C 1 168 ? 108.207 94.047  161.170 1.00 39.02  ? 168 PHE C N   1 
ATOM   6777  C CA  . PHE C 1 168 ? 107.327 94.651  160.181 1.00 39.02  ? 168 PHE C CA  1 
ATOM   6778  C C   . PHE C 1 168 ? 106.531 93.566  159.470 1.00 39.02  ? 168 PHE C C   1 
ATOM   6779  O O   . PHE C 1 168 ? 107.059 92.491  159.172 1.00 39.02  ? 168 PHE C O   1 
ATOM   6780  C CB  . PHE C 1 168 ? 108.123 95.454  159.153 1.00 39.02  ? 168 PHE C CB  1 
ATOM   6781  C CG  . PHE C 1 168 ? 108.476 96.839  159.598 1.00 39.02  ? 168 PHE C CG  1 
ATOM   6782  C CD1 . PHE C 1 168 ? 107.813 97.437  160.649 1.00 39.02  ? 168 PHE C CD1 1 
ATOM   6783  C CD2 . PHE C 1 168 ? 109.473 97.547  158.957 1.00 39.02  ? 168 PHE C CD2 1 
ATOM   6784  C CE1 . PHE C 1 168 ? 108.142 98.713  161.054 1.00 39.02  ? 168 PHE C CE1 1 
ATOM   6785  C CE2 . PHE C 1 168 ? 109.804 98.820  159.357 1.00 39.02  ? 168 PHE C CE2 1 
ATOM   6786  C CZ  . PHE C 1 168 ? 109.139 99.404  160.406 1.00 39.02  ? 168 PHE C CZ  1 
ATOM   6787  N N   . GLU C 1 169 ? 105.261 93.851  159.199 1.00 36.07  ? 169 GLU C N   1 
ATOM   6788  C CA  . GLU C 1 169 ? 104.430 92.930  158.438 1.00 36.07  ? 169 GLU C CA  1 
ATOM   6789  C C   . GLU C 1 169 ? 103.295 93.710  157.794 1.00 36.07  ? 169 GLU C C   1 
ATOM   6790  O O   . GLU C 1 169 ? 102.852 94.732  158.320 1.00 36.07  ? 169 GLU C O   1 
ATOM   6791  C CB  . GLU C 1 169 ? 103.883 91.804  159.320 1.00 36.07  ? 169 GLU C CB  1 
ATOM   6792  C CG  . GLU C 1 169 ? 102.946 92.270  160.412 1.00 36.07  ? 169 GLU C CG  1 
ATOM   6793  C CD  . GLU C 1 169 ? 102.710 91.204  161.461 1.00 36.07  ? 169 GLU C CD  1 
ATOM   6794  O OE1 . GLU C 1 169 ? 103.459 90.205  161.469 1.00 36.07  ? 169 GLU C OE1 1 
ATOM   6795  O OE2 . GLU C 1 169 ? 101.777 91.363  162.276 1.00 36.07  ? 169 GLU C OE2 1 
ATOM   6796  N N   . TRP C 1 170 ? 102.831 93.214  156.650 1.00 36.48  ? 170 TRP C N   1 
ATOM   6797  C CA  . TRP C 1 170 ? 101.774 93.884  155.912 1.00 36.48  ? 170 TRP C CA  1 
ATOM   6798  C C   . TRP C 1 170 ? 100.447 93.753  156.656 1.00 36.48  ? 170 TRP C C   1 
ATOM   6799  O O   . TRP C 1 170 ? 100.348 93.118  157.709 1.00 36.48  ? 170 TRP C O   1 
ATOM   6800  C CB  . TRP C 1 170 ? 101.659 93.304  154.506 1.00 36.48  ? 170 TRP C CB  1 
ATOM   6801  C CG  . TRP C 1 170 ? 102.731 93.749  153.570 1.00 36.48  ? 170 TRP C CG  1 
ATOM   6802  C CD1 . TRP C 1 170 ? 103.689 92.970  152.999 1.00 36.48  ? 170 TRP C CD1 1 
ATOM   6803  C CD2 . TRP C 1 170 ? 102.949 95.076  153.080 1.00 36.48  ? 170 TRP C CD2 1 
ATOM   6804  N NE1 . TRP C 1 170 ? 104.495 93.728  152.189 1.00 36.48  ? 170 TRP C NE1 1 
ATOM   6805  C CE2 . TRP C 1 170 ? 104.059 95.025  152.220 1.00 36.48  ? 170 TRP C CE2 1 
ATOM   6806  C CE3 . TRP C 1 170 ? 102.314 96.300  153.285 1.00 36.48  ? 170 TRP C CE3 1 
ATOM   6807  C CZ2 . TRP C 1 170 ? 104.550 96.151  151.570 1.00 36.48  ? 170 TRP C CZ2 1 
ATOM   6808  C CZ3 . TRP C 1 170 ? 102.804 97.415  152.641 1.00 36.48  ? 170 TRP C CZ3 1 
ATOM   6809  C CH2 . TRP C 1 170 ? 103.910 97.335  151.794 1.00 36.48  ? 170 TRP C CH2 1 
ATOM   6810  N N   . GLN C 1 171 ? 99.408  94.360  156.094 1.00 42.48  ? 171 GLN C N   1 
ATOM   6811  C CA  . GLN C 1 171 ? 98.074  94.258  156.658 1.00 42.48  ? 171 GLN C CA  1 
ATOM   6812  C C   . GLN C 1 171 ? 97.351  93.035  156.099 1.00 42.48  ? 171 GLN C C   1 
ATOM   6813  O O   . GLN C 1 171 ? 97.764  92.432  155.106 1.00 42.48  ? 171 GLN C O   1 
ATOM   6814  C CB  . GLN C 1 171 ? 97.270  95.526  156.382 1.00 42.48  ? 171 GLN C CB  1 
ATOM   6815  C CG  . GLN C 1 171 ? 96.291  95.870  157.485 1.00 42.48  ? 171 GLN C CG  1 
ATOM   6816  C CD  . GLN C 1 171 ? 95.980  97.346  157.549 1.00 42.48  ? 171 GLN C CD  1 
ATOM   6817  O OE1 . GLN C 1 171 ? 96.351  98.108  156.660 1.00 42.48  ? 171 GLN C OE1 1 
ATOM   6818  N NE2 . GLN C 1 171 ? 95.294  97.759  158.606 1.00 42.48  ? 171 GLN C NE2 1 
ATOM   6819  N N   . ASP C 1 172 ? 96.253  92.667  156.760 1.00 56.64  ? 172 ASP C N   1 
ATOM   6820  C CA  . ASP C 1 172 ? 95.525  91.463  156.375 1.00 56.64  ? 172 ASP C CA  1 
ATOM   6821  C C   . ASP C 1 172 ? 94.892  91.612  154.997 1.00 56.64  ? 172 ASP C C   1 
ATOM   6822  O O   . ASP C 1 172 ? 95.066  90.751  154.127 1.00 56.64  ? 172 ASP C O   1 
ATOM   6823  C CB  . ASP C 1 172 ? 94.465  91.137  157.426 1.00 56.64  ? 172 ASP C CB  1 
ATOM   6824  C CG  . ASP C 1 172 ? 94.992  90.230  158.519 1.00 56.64  ? 172 ASP C CG  1 
ATOM   6825  O OD1 . ASP C 1 172 ? 95.859  89.382  158.222 1.00 56.64  ? 172 ASP C OD1 1 
ATOM   6826  O OD2 . ASP C 1 172 ? 94.541  90.365  159.676 1.00 56.64  ? 172 ASP C OD2 1 
ATOM   6827  N N   . GLU C 1 173 ? 94.159  92.700  154.775 1.00 55.78  ? 173 GLU C N   1 
ATOM   6828  C CA  . GLU C 1 173 ? 93.471  92.926  153.514 1.00 55.78  ? 173 GLU C CA  1 
ATOM   6829  C C   . GLU C 1 173 ? 93.715  94.352  153.041 1.00 55.78  ? 173 GLU C C   1 
ATOM   6830  O O   . GLU C 1 173 ? 93.935  95.261  153.846 1.00 55.78  ? 173 GLU C O   1 
ATOM   6831  C CB  . GLU C 1 173 ? 91.962  92.661  153.639 1.00 55.78  ? 173 GLU C CB  1 
ATOM   6832  C CG  . GLU C 1 173 ? 91.149  93.846  154.132 1.00 55.78  ? 173 GLU C CG  1 
ATOM   6833  C CD  . GLU C 1 173 ? 91.509  94.255  155.546 1.00 55.78  ? 173 GLU C CD  1 
ATOM   6834  O OE1 . GLU C 1 173 ? 91.965  93.388  156.321 1.00 55.78  ? 173 GLU C OE1 1 
ATOM   6835  O OE2 . GLU C 1 173 ? 91.338  95.445  155.881 1.00 55.78  ? 173 GLU C OE2 1 
ATOM   6836  N N   . ALA C 1 174 ? 93.671  94.531  151.724 1.00 49.84  ? 174 ALA C N   1 
ATOM   6837  C CA  . ALA C 1 174 ? 93.949  95.809  151.081 1.00 49.84  ? 174 ALA C CA  1 
ATOM   6838  C C   . ALA C 1 174 ? 95.271  96.418  151.566 1.00 49.84  ? 174 ALA C C   1 
ATOM   6839  O O   . ALA C 1 174 ? 95.285  97.502  152.143 1.00 49.84  ? 174 ALA C O   1 
ATOM   6840  C CB  . ALA C 1 174 ? 92.801  96.785  151.297 1.00 49.84  ? 174 ALA C CB  1 
ATOM   6841  N N   . PRO C 1 175 ? 96.395  95.731  151.345 1.00 35.66  ? 175 PRO C N   1 
ATOM   6842  C CA  . PRO C 1 175 ? 97.674  96.241  151.854 1.00 35.66  ? 175 PRO C CA  1 
ATOM   6843  C C   . PRO C 1 175 ? 98.092  97.529  151.170 1.00 35.66  ? 175 PRO C C   1 
ATOM   6844  O O   . PRO C 1 175 ? 98.411  98.516  151.837 1.00 35.66  ? 175 PRO C O   1 
ATOM   6845  C CB  . PRO C 1 175 ? 98.655  95.102  151.549 1.00 35.66  ? 175 PRO C CB  1 
ATOM   6846  C CG  . PRO C 1 175 ? 97.796  93.914  151.243 1.00 35.66  ? 175 PRO C CG  1 
ATOM   6847  C CD  . PRO C 1 175 ? 96.571  94.469  150.615 1.00 35.66  ? 175 PRO C CD  1 
ATOM   6848  N N   . VAL C 1 176 ? 98.095  97.536  149.842 1.00 32.02  ? 176 VAL C N   1 
ATOM   6849  C CA  . VAL C 1 176 ? 98.438  98.721  149.068 1.00 32.02  ? 176 VAL C CA  1 
ATOM   6850  C C   . VAL C 1 176 ? 97.330  98.957  148.054 1.00 32.02  ? 176 VAL C C   1 
ATOM   6851  O O   . VAL C 1 176 ? 97.026  98.072  147.246 1.00 32.02  ? 176 VAL C O   1 
ATOM   6852  C CB  . VAL C 1 176 ? 99.800  98.582  148.371 1.00 32.02  ? 176 VAL C CB  1 
ATOM   6853  C CG1 . VAL C 1 176 ? 100.011 97.160  147.898 1.00 32.02  ? 176 VAL C CG1 1 
ATOM   6854  C CG2 . VAL C 1 176 ? 99.900  99.549  147.209 1.00 32.02  ? 176 VAL C CG2 1 
ATOM   6855  N N   . GLN C 1 177 ? 96.725  100.140 148.098 1.00 31.75  ? 177 GLN C N   1 
ATOM   6856  C CA  . GLN C 1 177 ? 95.649  100.509 147.191 1.00 31.75  ? 177 GLN C CA  1 
ATOM   6857  C C   . GLN C 1 177 ? 96.057  101.746 146.408 1.00 31.75  ? 177 GLN C C   1 
ATOM   6858  O O   . GLN C 1 177 ? 96.585  102.703 146.982 1.00 31.75  ? 177 GLN C O   1 
ATOM   6859  C CB  . GLN C 1 177 ? 94.343  100.768 147.948 1.00 31.75  ? 177 GLN C CB  1 
ATOM   6860  C CG  . GLN C 1 177 ? 94.458  101.754 149.095 1.00 31.75  ? 177 GLN C CG  1 
ATOM   6861  C CD  . GLN C 1 177 ? 94.810  101.086 150.405 1.00 31.75  ? 177 GLN C CD  1 
ATOM   6862  O OE1 . GLN C 1 177 ? 95.157  99.907  150.437 1.00 31.75  ? 177 GLN C OE1 1 
ATOM   6863  N NE2 . GLN C 1 177 ? 94.719  101.835 151.496 1.00 31.75  ? 177 GLN C NE2 1 
ATOM   6864  N N   . VAL C 1 178 ? 95.821  101.722 145.113 1.00 30.46  ? 178 VAL C N   1 
ATOM   6865  C CA  . VAL C 1 178 ? 96.130  102.854 144.250 1.00 30.46  ? 178 VAL C CA  1 
ATOM   6866  C C   . VAL C 1 178 ? 94.924  103.775 144.203 1.00 30.46  ? 178 VAL C C   1 
ATOM   6867  O O   . VAL C 1 178 ? 93.775  103.338 144.315 1.00 30.46  ? 178 VAL C O   1 
ATOM   6868  C CB  . VAL C 1 178 ? 96.537  102.383 142.840 1.00 30.46  ? 178 VAL C CB  1 
ATOM   6869  C CG1 . VAL C 1 178 ? 97.895  101.712 142.881 1.00 30.46  ? 178 VAL C CG1 1 
ATOM   6870  C CG2 . VAL C 1 178 ? 95.493  101.436 142.281 1.00 30.46  ? 178 VAL C CG2 1 
ATOM   6871  N N   . ALA C 1 179 ? 95.185  105.068 144.044 1.00 31.92  ? 179 ALA C N   1 
ATOM   6872  C CA  . ALA C 1 179 ? 94.106  106.038 143.957 1.00 31.92  ? 179 ALA C CA  1 
ATOM   6873  C C   . ALA C 1 179 ? 93.322  105.849 142.665 1.00 31.92  ? 179 ALA C C   1 
ATOM   6874  O O   . ALA C 1 179 ? 93.872  105.467 141.629 1.00 31.92  ? 179 ALA C O   1 
ATOM   6875  C CB  . ALA C 1 179 ? 94.657  107.460 144.031 1.00 31.92  ? 179 ALA C CB  1 
ATOM   6876  N N   . GLU C 1 180 ? 92.021  106.116 142.737 1.00 35.95  ? 180 GLU C N   1 
ATOM   6877  C CA  . GLU C 1 180 ? 91.166  105.967 141.567 1.00 35.95  ? 180 GLU C CA  1 
ATOM   6878  C C   . GLU C 1 180 ? 91.596  106.927 140.466 1.00 35.95  ? 180 GLU C C   1 
ATOM   6879  O O   . GLU C 1 180 ? 91.895  108.097 140.719 1.00 35.95  ? 180 GLU C O   1 
ATOM   6880  C CB  . GLU C 1 180 ? 89.705  106.214 141.944 1.00 35.95  ? 180 GLU C CB  1 
ATOM   6881  N N   . GLY C 1 181 ? 91.627  106.424 139.235 1.00 35.16  ? 181 GLY C N   1 
ATOM   6882  C CA  . GLY C 1 181 ? 92.038  107.228 138.105 1.00 35.16  ? 181 GLY C CA  1 
ATOM   6883  C C   . GLY C 1 181 ? 93.531  107.367 137.922 1.00 35.16  ? 181 GLY C C   1 
ATOM   6884  O O   . GLY C 1 181 ? 93.964  108.237 137.158 1.00 35.16  ? 181 GLY C O   1 
ATOM   6885  N N   . LEU C 1 182 ? 94.331  106.547 138.597 1.00 39.34  ? 182 LEU C N   1 
ATOM   6886  C CA  . LEU C 1 182 ? 95.778  106.620 138.452 1.00 39.34  ? 182 LEU C CA  1 
ATOM   6887  C C   . LEU C 1 182 ? 96.201  106.197 137.052 1.00 39.34  ? 182 LEU C C   1 
ATOM   6888  O O   . LEU C 1 182 ? 95.714  105.200 136.512 1.00 39.34  ? 182 LEU C O   1 
ATOM   6889  C CB  . LEU C 1 182 ? 96.458  105.735 139.495 1.00 39.34  ? 182 LEU C CB  1 
ATOM   6890  C CG  . LEU C 1 182 ? 97.964  105.529 139.343 1.00 39.34  ? 182 LEU C CG  1 
ATOM   6891  C CD1 . LEU C 1 182 ? 98.691  106.857 139.421 1.00 39.34  ? 182 LEU C CD1 1 
ATOM   6892  C CD2 . LEU C 1 182 ? 98.472  104.574 140.404 1.00 39.34  ? 182 LEU C CD2 1 
ATOM   6893  N N   . THR C 1 183 ? 97.121  106.960 136.465 1.00 44.12  ? 183 THR C N   1 
ATOM   6894  C CA  . THR C 1 183 ? 97.610  106.690 135.123 1.00 44.12  ? 183 THR C CA  1 
ATOM   6895  C C   . THR C 1 183 ? 99.107  106.955 135.065 1.00 44.12  ? 183 THR C C   1 
ATOM   6896  O O   . THR C 1 183 ? 99.670  107.653 135.910 1.00 44.12  ? 183 THR C O   1 
ATOM   6897  C CB  . THR C 1 183 ? 96.893  107.542 134.069 1.00 44.12  ? 183 THR C CB  1 
ATOM   6898  O OG1 . THR C 1 183 ? 97.586  107.440 132.819 1.00 44.12  ? 183 THR C OG1 1 
ATOM   6899  C CG2 . THR C 1 183 ? 96.853  108.997 134.500 1.00 44.12  ? 183 THR C CG2 1 
ATOM   6900  N N   . LEU C 1 184 ? 99.743  106.386 134.047 1.00 46.70  ? 184 LEU C N   1 
ATOM   6901  C CA  . LEU C 1 184 ? 101.166 106.546 133.806 1.00 46.70  ? 184 LEU C CA  1 
ATOM   6902  C C   . LEU C 1 184 ? 101.388 107.014 132.376 1.00 46.70  ? 184 LEU C C   1 
ATOM   6903  O O   . LEU C 1 184 ? 100.568 106.739 131.495 1.00 46.70  ? 184 LEU C O   1 
ATOM   6904  C CB  . LEU C 1 184 ? 101.922 105.231 134.043 1.00 46.70  ? 184 LEU C CB  1 
ATOM   6905  C CG  . LEU C 1 184 ? 102.067 104.794 135.499 1.00 46.70  ? 184 LEU C CG  1 
ATOM   6906  C CD1 . LEU C 1 184 ? 100.883 103.949 135.929 1.00 46.70  ? 184 LEU C CD1 1 
ATOM   6907  C CD2 . LEU C 1 184 ? 103.364 104.035 135.689 1.00 46.70  ? 184 LEU C CD2 1 
ATOM   6908  N N   . PRO C 1 185 ? 102.480 107.739 132.121 1.00 52.31  ? 185 PRO C N   1 
ATOM   6909  C CA  . PRO C 1 185 ? 102.694 108.267 130.762 1.00 52.31  ? 185 PRO C CA  1 
ATOM   6910  C C   . PRO C 1 185 ? 102.799 107.193 129.694 1.00 52.31  ? 185 PRO C C   1 
ATOM   6911  O O   . PRO C 1 185 ? 102.251 107.365 128.598 1.00 52.31  ? 185 PRO C O   1 
ATOM   6912  C CB  . PRO C 1 185 ? 104.001 109.062 130.900 1.00 52.31  ? 185 PRO C CB  1 
ATOM   6913  C CG  . PRO C 1 185 ? 104.666 108.510 132.121 1.00 52.31  ? 185 PRO C CG  1 
ATOM   6914  C CD  . PRO C 1 185 ? 103.554 108.137 133.046 1.00 52.31  ? 185 PRO C CD  1 
ATOM   6915  N N   . GLN C 1 186 ? 103.477 106.081 129.980 1.00 53.50  ? 186 GLN C N   1 
ATOM   6916  C CA  . GLN C 1 186 ? 103.734 105.089 128.944 1.00 53.50  ? 186 GLN C CA  1 
ATOM   6917  C C   . GLN C 1 186 ? 103.609 103.652 129.434 1.00 53.50  ? 186 GLN C C   1 
ATOM   6918  O O   . GLN C 1 186 ? 103.973 102.731 128.694 1.00 53.50  ? 186 GLN C O   1 
ATOM   6919  C CB  . GLN C 1 186 ? 105.128 105.304 128.343 1.00 53.50  ? 186 GLN C CB  1 
ATOM   6920  C CG  . GLN C 1 186 ? 105.238 104.911 126.881 1.00 53.50  ? 186 GLN C CG  1 
ATOM   6921  C CD  . GLN C 1 186 ? 106.637 104.476 126.499 1.00 53.50  ? 186 GLN C CD  1 
ATOM   6922  O OE1 . GLN C 1 186 ? 106.818 103.489 125.787 1.00 53.50  ? 186 GLN C OE1 1 
ATOM   6923  N NE2 . GLN C 1 186 ? 107.637 105.213 126.968 1.00 53.50  ? 186 GLN C NE2 1 
ATOM   6924  N N   . PHE C 1 187 ? 103.110 103.419 130.643 1.00 50.00  ? 187 PHE C N   1 
ATOM   6925  C CA  . PHE C 1 187 ? 103.047 102.079 131.201 1.00 50.00  ? 187 PHE C CA  1 
ATOM   6926  C C   . PHE C 1 187 ? 101.644 101.793 131.710 1.00 50.00  ? 187 PHE C C   1 
ATOM   6927  O O   . PHE C 1 187 ? 100.842 102.701 131.937 1.00 50.00  ? 187 PHE C O   1 
ATOM   6928  C CB  . PHE C 1 187 ? 104.055 101.890 132.340 1.00 50.00  ? 187 PHE C CB  1 
ATOM   6929  C CG  . PHE C 1 187 ? 105.484 102.066 131.926 1.00 50.00  ? 187 PHE C CG  1 
ATOM   6930  C CD1 . PHE C 1 187 ? 106.011 103.328 131.717 1.00 50.00  ? 187 PHE C CD1 1 
ATOM   6931  C CD2 . PHE C 1 187 ? 106.306 100.968 131.760 1.00 50.00  ? 187 PHE C CD2 1 
ATOM   6932  C CE1 . PHE C 1 187 ? 107.326 103.491 131.342 1.00 50.00  ? 187 PHE C CE1 1 
ATOM   6933  C CE2 . PHE C 1 187 ? 107.623 101.125 131.386 1.00 50.00  ? 187 PHE C CE2 1 
ATOM   6934  C CZ  . PHE C 1 187 ? 108.134 102.388 131.176 1.00 50.00  ? 187 PHE C CZ  1 
ATOM   6935  N N   . LEU C 1 188 ? 101.354 100.508 131.881 1.00 50.24  ? 188 LEU C N   1 
ATOM   6936  C CA  . LEU C 1 188 ? 100.109 100.050 132.480 1.00 50.24  ? 188 LEU C CA  1 
ATOM   6937  C C   . LEU C 1 188 ? 100.438 99.307  133.767 1.00 50.24  ? 188 LEU C C   1 
ATOM   6938  O O   . LEU C 1 188 ? 101.209 98.342  133.749 1.00 50.24  ? 188 LEU C O   1 
ATOM   6939  C CB  . LEU C 1 188 ? 99.335  99.150  131.518 1.00 50.24  ? 188 LEU C CB  1 
ATOM   6940  C CG  . LEU C 1 188 ? 98.113  98.442  132.104 1.00 50.24  ? 188 LEU C CG  1 
ATOM   6941  C CD1 . LEU C 1 188 ? 97.068  99.454  132.545 1.00 50.24  ? 188 LEU C CD1 1 
ATOM   6942  C CD2 . LEU C 1 188 ? 97.524  97.461  131.101 1.00 50.24  ? 188 LEU C CD2 1 
ATOM   6943  N N   . LEU C 1 189 ? 99.856  99.755  134.875 1.00 46.59  ? 189 LEU C N   1 
ATOM   6944  C CA  . LEU C 1 189 ? 100.078 99.148  136.186 1.00 46.59  ? 189 LEU C CA  1 
ATOM   6945  C C   . LEU C 1 189 ? 98.954  98.150  136.429 1.00 46.59  ? 189 LEU C C   1 
ATOM   6946  O O   . LEU C 1 189 ? 97.831  98.534  136.764 1.00 46.59  ? 189 LEU C O   1 
ATOM   6947  C CB  . LEU C 1 189 ? 100.128 100.216 137.274 1.00 46.59  ? 189 LEU C CB  1 
ATOM   6948  C CG  . LEU C 1 189 ? 100.863 99.871  138.568 1.00 46.59  ? 189 LEU C CG  1 
ATOM   6949  C CD1 . LEU C 1 189 ? 101.445 101.124 139.189 1.00 46.59  ? 189 LEU C CD1 1 
ATOM   6950  C CD2 . LEU C 1 189 ? 99.936  99.179  139.548 1.00 46.59  ? 189 LEU C CD2 1 
ATOM   6951  N N   . LYS C 1 190 ? 99.256  96.866  136.260 1.00 51.33  ? 190 LYS C N   1 
ATOM   6952  C CA  . LYS C 1 190 ? 98.233  95.846  136.423 1.00 51.33  ? 190 LYS C CA  1 
ATOM   6953  C C   . LYS C 1 190 ? 97.851  95.697  137.892 1.00 51.33  ? 190 LYS C C   1 
ATOM   6954  O O   . LYS C 1 190 ? 98.620  96.015  138.803 1.00 51.33  ? 190 LYS C O   1 
ATOM   6955  C CB  . LYS C 1 190 ? 98.704  94.511  135.848 1.00 51.33  ? 190 LYS C CB  1 
ATOM   6956  C CG  . LYS C 1 190 ? 100.095 94.091  136.271 1.00 51.33  ? 190 LYS C CG  1 
ATOM   6957  C CD  . LYS C 1 190 ? 100.697 93.121  135.266 1.00 51.33  ? 190 LYS C CD  1 
ATOM   6958  C CE  . LYS C 1 190 ? 99.704  92.044  134.858 1.00 51.33  ? 190 LYS C CE  1 
ATOM   6959  N NZ  . LYS C 1 190 ? 99.265  91.219  136.016 1.00 51.33  ? 190 LYS C NZ  1 
ATOM   6960  N N   . GLU C 1 191 ? 96.629  95.205  138.110 1.00 55.58  ? 191 GLU C N   1 
ATOM   6961  C CA  . GLU C 1 191 ? 96.053  95.188  139.450 1.00 55.58  ? 191 GLU C CA  1 
ATOM   6962  C C   . GLU C 1 191 ? 96.852  94.306  140.401 1.00 55.58  ? 191 GLU C C   1 
ATOM   6963  O O   . GLU C 1 191 ? 97.088  94.683  141.554 1.00 55.58  ? 191 GLU C O   1 
ATOM   6964  C CB  . GLU C 1 191 ? 94.599  94.721  139.380 1.00 55.58  ? 191 GLU C CB  1 
ATOM   6965  C CG  . GLU C 1 191 ? 94.061  94.153  140.680 1.00 55.58  ? 191 GLU C CG  1 
ATOM   6966  C CD  . GLU C 1 191 ? 93.936  95.200  141.764 1.00 55.58  ? 191 GLU C CD  1 
ATOM   6967  O OE1 . GLU C 1 191 ? 93.751  96.388  141.424 1.00 55.58  ? 191 GLU C OE1 1 
ATOM   6968  O OE2 . GLU C 1 191 ? 94.022  94.837  142.956 1.00 55.58  ? 191 GLU C OE2 1 
ATOM   6969  N N   . GLU C 1 192 ? 97.278  93.133  139.941 1.00 54.30  ? 192 GLU C N   1 
ATOM   6970  C CA  . GLU C 1 192 ? 97.913  92.170  140.830 1.00 54.30  ? 192 GLU C CA  1 
ATOM   6971  C C   . GLU C 1 192 ? 99.261  92.685  141.321 1.00 54.30  ? 192 GLU C C   1 
ATOM   6972  O O   . GLU C 1 192 ? 100.100 93.123  140.528 1.00 54.30  ? 192 GLU C O   1 
ATOM   6973  C CB  . GLU C 1 192 ? 98.087  90.829  140.120 1.00 54.30  ? 192 GLU C CB  1 
ATOM   6974  C CG  . GLU C 1 192 ? 98.391  89.672  141.056 1.00 54.30  ? 192 GLU C CG  1 
ATOM   6975  C CD  . GLU C 1 192 ? 97.263  89.394  142.031 1.00 54.30  ? 192 GLU C CD  1 
ATOM   6976  O OE1 . GLU C 1 192 ? 96.097  89.704  141.705 1.00 54.30  ? 192 GLU C OE1 1 
ATOM   6977  O OE2 . GLU C 1 192 ? 97.541  88.863  143.126 1.00 54.30  ? 192 GLU C OE2 1 
ATOM   6978  N N   . LYS C 1 193 ? 99.464  92.626  142.636 1.00 46.38  ? 193 LYS C N   1 
ATOM   6979  C CA  . LYS C 1 193 ? 100.704 93.041  143.274 1.00 46.38  ? 193 LYS C CA  1 
ATOM   6980  C C   . LYS C 1 193 ? 101.161 91.949  144.228 1.00 46.38  ? 193 LYS C C   1 
ATOM   6981  O O   . LYS C 1 193 ? 100.342 91.331  144.913 1.00 46.38  ? 193 LYS C O   1 
ATOM   6982  C CB  . LYS C 1 193 ? 100.527 94.361  144.030 1.00 46.38  ? 193 LYS C CB  1 
ATOM   6983  C CG  . LYS C 1 193 ? 100.011 95.499  143.171 1.00 46.38  ? 193 LYS C CG  1 
ATOM   6984  C CD  . LYS C 1 193 ? 99.920  96.789  143.961 1.00 46.38  ? 193 LYS C CD  1 
ATOM   6985  C CE  . LYS C 1 193 ? 99.369  97.915  143.109 1.00 46.38  ? 193 LYS C CE  1 
ATOM   6986  N NZ  . LYS C 1 193 ? 97.997  97.610  142.627 1.00 46.38  ? 193 LYS C NZ  1 
ATOM   6987  N N   . ASP C 1 194 ? 102.469 91.717  144.273 1.00 46.01  ? 194 ASP C N   1 
ATOM   6988  C CA  . ASP C 1 194 ? 103.044 90.633  145.057 1.00 46.01  ? 194 ASP C CA  1 
ATOM   6989  C C   . ASP C 1 194 ? 103.660 91.180  146.337 1.00 46.01  ? 194 ASP C C   1 
ATOM   6990  O O   . ASP C 1 194 ? 104.357 92.198  146.311 1.00 46.01  ? 194 ASP C O   1 
ATOM   6991  C CB  . ASP C 1 194 ? 104.099 89.880  144.247 1.00 46.01  ? 194 ASP C CB  1 
ATOM   6992  C CG  . ASP C 1 194 ? 103.508 89.148  143.061 1.00 46.01  ? 194 ASP C CG  1 
ATOM   6993  O OD1 . ASP C 1 194 ? 102.387 88.615  143.192 1.00 46.01  ? 194 ASP C OD1 1 
ATOM   6994  O OD2 . ASP C 1 194 ? 104.164 89.106  141.999 1.00 46.01  ? 194 ASP C OD2 1 
ATOM   6995  N N   . LEU C 1 195 ? 103.397 90.501  147.451 1.00 40.27  ? 195 LEU C N   1 
ATOM   6996  C CA  . LEU C 1 195 ? 103.954 90.850  148.751 1.00 40.27  ? 195 LEU C CA  1 
ATOM   6997  C C   . LEU C 1 195 ? 104.840 89.710  149.227 1.00 40.27  ? 195 LEU C C   1 
ATOM   6998  O O   . LEU C 1 195 ? 104.416 88.550  149.226 1.00 40.27  ? 195 LEU C O   1 
ATOM   6999  C CB  . LEU C 1 195 ? 102.850 91.112  149.775 1.00 40.27  ? 195 LEU C CB  1 
ATOM   7000  C CG  . LEU C 1 195 ? 101.604 91.887  149.347 1.00 40.27  ? 195 LEU C CG  1 
ATOM   7001  C CD1 . LEU C 1 195 ? 100.795 92.230  150.573 1.00 40.27  ? 195 LEU C CD1 1 
ATOM   7002  C CD2 . LEU C 1 195 ? 101.969 93.153  148.597 1.00 40.27  ? 195 LEU C CD2 1 
ATOM   7003  N N   . ARG C 1 196 ? 106.065 90.035  149.633 1.00 48.25  ? 196 ARG C N   1 
ATOM   7004  C CA  . ARG C 1 196 ? 107.027 89.032  150.061 1.00 48.25  ? 196 ARG C CA  1 
ATOM   7005  C C   . ARG C 1 196 ? 107.720 89.480  151.340 1.00 48.25  ? 196 ARG C C   1 
ATOM   7006  O O   . ARG C 1 196 ? 107.781 90.670  151.656 1.00 48.25  ? 196 ARG C O   1 
ATOM   7007  C CB  . ARG C 1 196 ? 108.083 88.759  148.979 1.00 48.25  ? 196 ARG C CB  1 
ATOM   7008  C CG  . ARG C 1 196 ? 107.547 88.703  147.560 1.00 48.25  ? 196 ARG C CG  1 
ATOM   7009  C CD  . ARG C 1 196 ? 108.539 88.034  146.622 1.00 48.25  ? 196 ARG C CD  1 
ATOM   7010  N NE  . ARG C 1 196 ? 109.905 88.496  146.842 1.00 48.25  ? 196 ARG C NE  1 
ATOM   7011  C CZ  . ARG C 1 196 ? 110.892 87.732  147.290 1.00 48.25  ? 196 ARG C CZ  1 
ATOM   7012  N NH1 . ARG C 1 196 ? 110.701 86.455  147.578 1.00 48.25  ? 196 ARG C NH1 1 
ATOM   7013  N NH2 . ARG C 1 196 ? 112.100 88.262  147.453 1.00 48.25  ? 196 ARG C NH2 1 
ATOM   7014  N N   . TYR C 1 197 ? 108.242 88.502  152.075 1.00 48.69  ? 197 TYR C N   1 
ATOM   7015  C CA  . TYR C 1 197 ? 109.078 88.763  153.240 1.00 48.69  ? 197 TYR C CA  1 
ATOM   7016  C C   . TYR C 1 197 ? 110.521 88.927  152.785 1.00 48.69  ? 197 TYR C C   1 
ATOM   7017  O O   . TYR C 1 197 ? 111.122 87.990  152.251 1.00 48.69  ? 197 TYR C O   1 
ATOM   7018  C CB  . TYR C 1 197 ? 108.968 87.636  154.264 1.00 48.69  ? 197 TYR C CB  1 
ATOM   7019  C CG  . TYR C 1 197 ? 107.895 87.852  155.301 1.00 48.69  ? 197 TYR C CG  1 
ATOM   7020  C CD1 . TYR C 1 197 ? 107.220 89.060  155.387 1.00 48.69  ? 197 TYR C CD1 1 
ATOM   7021  C CD2 . TYR C 1 197 ? 107.564 86.849  156.201 1.00 48.69  ? 197 TYR C CD2 1 
ATOM   7022  C CE1 . TYR C 1 197 ? 106.239 89.261  156.336 1.00 48.69  ? 197 TYR C CE1 1 
ATOM   7023  C CE2 . TYR C 1 197 ? 106.586 87.040  157.154 1.00 48.69  ? 197 TYR C CE2 1 
ATOM   7024  C CZ  . TYR C 1 197 ? 105.926 88.248  157.218 1.00 48.69  ? 197 TYR C CZ  1 
ATOM   7025  O OH  . TYR C 1 197 ? 104.950 88.443  158.167 1.00 48.69  ? 197 TYR C OH  1 
ATOM   7026  N N   . CYS C 1 198 ? 111.072 90.118  153.000 1.00 42.20  ? 198 CYS C N   1 
ATOM   7027  C CA  . CYS C 1 198 ? 112.440 90.413  152.579 1.00 42.20  ? 198 CYS C CA  1 
ATOM   7028  C C   . CYS C 1 198 ? 113.450 89.901  153.604 1.00 42.20  ? 198 CYS C C   1 
ATOM   7029  O O   . CYS C 1 198 ? 114.253 89.012  153.307 1.00 42.20  ? 198 CYS C O   1 
ATOM   7030  C CB  . CYS C 1 198 ? 112.567 91.919  152.339 1.00 42.20  ? 198 CYS C CB  1 
ATOM   7031  S SG  . CYS C 1 198 ? 114.204 92.628  152.355 1.00 42.20  ? 198 CYS C SG  1 
ATOM   7032  N N   . THR C 1 199 ? 113.406 90.446  154.820 1.00 36.51  ? 199 THR C N   1 
ATOM   7033  C CA  . THR C 1 199 ? 114.172 89.960  155.972 1.00 36.51  ? 199 THR C CA  1 
ATOM   7034  C C   . THR C 1 199 ? 115.644 89.726  155.629 1.00 36.51  ? 199 THR C C   1 
ATOM   7035  O O   . THR C 1 199 ? 116.156 88.609  155.692 1.00 36.51  ? 199 THR C O   1 
ATOM   7036  C CB  . THR C 1 199 ? 113.544 88.685  156.536 1.00 36.51  ? 199 THR C CB  1 
ATOM   7037  O OG1 . THR C 1 199 ? 112.119 88.763  156.423 1.00 36.51  ? 199 THR C OG1 1 
ATOM   7038  C CG2 . THR C 1 199 ? 113.918 88.514  157.996 1.00 36.51  ? 199 THR C CG2 1 
ATOM   7039  N N   . LYS C 1 200 ? 116.326 90.807  155.267 1.00 35.58  ? 200 LYS C N   1 
ATOM   7040  C CA  . LYS C 1 200 ? 117.720 90.685  154.877 1.00 35.58  ? 200 LYS C CA  1 
ATOM   7041  C C   . LYS C 1 200 ? 118.620 90.571  156.107 1.00 35.58  ? 200 LYS C C   1 
ATOM   7042  O O   . LYS C 1 200 ? 118.211 90.829  157.241 1.00 35.58  ? 200 LYS C O   1 
ATOM   7043  C CB  . LYS C 1 200 ? 118.142 91.867  154.009 1.00 35.58  ? 200 LYS C CB  1 
ATOM   7044  C CG  . LYS C 1 200 ? 117.893 93.224  154.627 1.00 35.58  ? 200 LYS C CG  1 
ATOM   7045  C CD  . LYS C 1 200 ? 118.436 94.318  153.730 1.00 35.58  ? 200 LYS C CD  1 
ATOM   7046  C CE  . LYS C 1 200 ? 117.976 94.134  152.293 1.00 35.58  ? 200 LYS C CE  1 
ATOM   7047  N NZ  . LYS C 1 200 ? 118.723 95.013  151.353 1.00 35.58  ? 200 LYS C NZ  1 
ATOM   7048  N N   . HIS C 1 201 ? 119.867 90.178  155.864 1.00 36.23  ? 201 HIS C N   1 
ATOM   7049  C CA  . HIS C 1 201 ? 120.847 89.940  156.911 1.00 36.23  ? 201 HIS C CA  1 
ATOM   7050  C C   . HIS C 1 201 ? 122.003 90.922  156.790 1.00 36.23  ? 201 HIS C C   1 
ATOM   7051  O O   . HIS C 1 201 ? 122.362 91.355  155.692 1.00 36.23  ? 201 HIS C O   1 
ATOM   7052  C CB  . HIS C 1 201 ? 121.396 88.512  156.846 1.00 36.23  ? 201 HIS C CB  1 
ATOM   7053  C CG  . HIS C 1 201 ? 120.523 87.493  157.507 1.00 36.23  ? 201 HIS C CG  1 
ATOM   7054  N ND1 . HIS C 1 201 ? 119.488 86.863  156.852 1.00 36.23  ? 201 HIS C ND1 1 
ATOM   7055  C CD2 . HIS C 1 201 ? 120.546 86.978  158.759 1.00 36.23  ? 201 HIS C CD2 1 
ATOM   7056  C CE1 . HIS C 1 201 ? 118.902 86.012  157.676 1.00 36.23  ? 201 HIS C CE1 1 
ATOM   7057  N NE2 . HIS C 1 201 ? 119.528 86.060  158.838 1.00 36.23  ? 201 HIS C NE2 1 
ATOM   7058  N N   . TYR C 1 202 ? 122.589 91.259  157.935 1.00 36.93  ? 202 TYR C N   1 
ATOM   7059  C CA  . TYR C 1 202 ? 123.773 92.102  157.997 1.00 36.93  ? 202 TYR C CA  1 
ATOM   7060  C C   . TYR C 1 202 ? 124.707 91.545  159.058 1.00 36.93  ? 202 TYR C C   1 
ATOM   7061  O O   . TYR C 1 202 ? 124.312 90.731  159.895 1.00 36.93  ? 202 TYR C O   1 
ATOM   7062  C CB  . TYR C 1 202 ? 123.428 93.559  158.323 1.00 36.93  ? 202 TYR C CB  1 
ATOM   7063  C CG  . TYR C 1 202 ? 122.729 94.301  157.212 1.00 36.93  ? 202 TYR C CG  1 
ATOM   7064  C CD1 . TYR C 1 202 ? 123.270 94.350  155.937 1.00 36.93  ? 202 TYR C CD1 1 
ATOM   7065  C CD2 . TYR C 1 202 ? 121.536 94.969  157.442 1.00 36.93  ? 202 TYR C CD2 1 
ATOM   7066  C CE1 . TYR C 1 202 ? 122.635 95.033  154.921 1.00 36.93  ? 202 TYR C CE1 1 
ATOM   7067  C CE2 . TYR C 1 202 ? 120.896 95.656  156.434 1.00 36.93  ? 202 TYR C CE2 1 
ATOM   7068  C CZ  . TYR C 1 202 ? 121.449 95.685  155.175 1.00 36.93  ? 202 TYR C CZ  1 
ATOM   7069  O OH  . TYR C 1 202 ? 120.816 96.369  154.166 1.00 36.93  ? 202 TYR C OH  1 
ATOM   7070  N N   . ASN C 1 203 ? 125.962 91.995  159.019 1.00 35.75  ? 203 ASN C N   1 
ATOM   7071  C CA  . ASN C 1 203 ? 126.914 91.582  160.042 1.00 35.75  ? 203 ASN C CA  1 
ATOM   7072  C C   . ASN C 1 203 ? 126.620 92.201  161.401 1.00 35.75  ? 203 ASN C C   1 
ATOM   7073  O O   . ASN C 1 203 ? 127.215 91.775  162.396 1.00 35.75  ? 203 ASN C O   1 
ATOM   7074  C CB  . ASN C 1 203 ? 128.341 91.931  159.615 1.00 35.75  ? 203 ASN C CB  1 
ATOM   7075  C CG  . ASN C 1 203 ? 128.504 93.394  159.264 1.00 35.75  ? 203 ASN C CG  1 
ATOM   7076  O OD1 . ASN C 1 203 ? 127.532 94.147  159.225 1.00 35.75  ? 203 ASN C OD1 1 
ATOM   7077  N ND2 . ASN C 1 203 ? 129.740 93.807  159.012 1.00 35.75  ? 203 ASN C ND2 1 
ATOM   7078  N N   . THR C 1 204 ? 125.729 93.187  161.468 1.00 37.92  ? 204 THR C N   1 
ATOM   7079  C CA  . THR C 1 204 ? 125.373 93.828  162.725 1.00 37.92  ? 204 THR C CA  1 
ATOM   7080  C C   . THR C 1 204 ? 124.159 93.201  163.395 1.00 37.92  ? 204 THR C C   1 
ATOM   7081  O O   . THR C 1 204 ? 123.788 93.631  164.491 1.00 37.92  ? 204 THR C O   1 
ATOM   7082  C CB  . THR C 1 204 ? 125.112 95.320  162.507 1.00 37.92  ? 204 THR C CB  1 
ATOM   7083  O OG1 . THR C 1 204 ? 124.915 95.959  163.774 1.00 37.92  ? 204 THR C OG1 1 
ATOM   7084  C CG2 . THR C 1 204 ? 123.873 95.517  161.658 1.00 37.92  ? 204 THR C CG2 1 
ATOM   7085  N N   . GLY C 1 205 ? 123.529 92.213  162.772 1.00 38.23  ? 205 GLY C N   1 
ATOM   7086  C CA  . GLY C 1 205 ? 122.415 91.517  163.373 1.00 38.23  ? 205 GLY C CA  1 
ATOM   7087  C C   . GLY C 1 205 ? 121.389 91.131  162.332 1.00 38.23  ? 205 GLY C C   1 
ATOM   7088  O O   . GLY C 1 205 ? 121.655 91.135  161.132 1.00 38.23  ? 205 GLY C O   1 
ATOM   7089  N N   . LYS C 1 206 ? 120.198 90.788  162.813 1.00 37.70  ? 206 LYS C N   1 
ATOM   7090  C CA  . LYS C 1 206 ? 119.078 90.393  161.969 1.00 37.70  ? 206 LYS C CA  1 
ATOM   7091  C C   . LYS C 1 206 ? 118.090 91.550  161.889 1.00 37.70  ? 206 LYS C C   1 
ATOM   7092  O O   . LYS C 1 206 ? 117.515 91.949  162.906 1.00 37.70  ? 206 LYS C O   1 
ATOM   7093  C CB  . LYS C 1 206 ? 118.400 89.146  162.532 1.00 37.70  ? 206 LYS C CB  1 
ATOM   7094  C CG  . LYS C 1 206 ? 117.175 88.692  161.766 1.00 37.70  ? 206 LYS C CG  1 
ATOM   7095  C CD  . LYS C 1 206 ? 117.533 87.640  160.739 1.00 37.70  ? 206 LYS C CD  1 
ATOM   7096  C CE  . LYS C 1 206 ? 116.363 86.711  160.467 1.00 37.70  ? 206 LYS C CE  1 
ATOM   7097  N NZ  . LYS C 1 206 ? 115.883 86.048  161.710 1.00 37.70  ? 206 LYS C NZ  1 
ATOM   7098  N N   . PHE C 1 207 ? 117.885 92.077  160.687 1.00 36.13  ? 207 PHE C N   1 
ATOM   7099  C CA  . PHE C 1 207 ? 117.069 93.264  160.480 1.00 36.13  ? 207 PHE C CA  1 
ATOM   7100  C C   . PHE C 1 207 ? 115.807 92.903  159.711 1.00 36.13  ? 207 PHE C C   1 
ATOM   7101  O O   . PHE C 1 207 ? 115.878 92.237  158.674 1.00 36.13  ? 207 PHE C O   1 
ATOM   7102  C CB  . PHE C 1 207 ? 117.854 94.339  159.729 1.00 36.13  ? 207 PHE C CB  1 
ATOM   7103  C CG  . PHE C 1 207 ? 118.758 95.149  160.607 1.00 36.13  ? 207 PHE C CG  1 
ATOM   7104  C CD1 . PHE C 1 207 ? 118.779 94.947  161.974 1.00 36.13  ? 207 PHE C CD1 1 
ATOM   7105  C CD2 . PHE C 1 207 ? 119.582 96.118  160.068 1.00 36.13  ? 207 PHE C CD2 1 
ATOM   7106  C CE1 . PHE C 1 207 ? 119.606 95.692  162.784 1.00 36.13  ? 207 PHE C CE1 1 
ATOM   7107  C CE2 . PHE C 1 207 ? 120.412 96.866  160.875 1.00 36.13  ? 207 PHE C CE2 1 
ATOM   7108  C CZ  . PHE C 1 207 ? 120.423 96.652  162.234 1.00 36.13  ? 207 PHE C CZ  1 
ATOM   7109  N N   . THR C 1 208 ? 114.660 93.346  160.219 1.00 33.33  ? 208 THR C N   1 
ATOM   7110  C CA  . THR C 1 208 ? 113.395 93.107  159.541 1.00 33.33  ? 208 THR C CA  1 
ATOM   7111  C C   . THR C 1 208 ? 113.317 93.913  158.252 1.00 33.33  ? 208 THR C C   1 
ATOM   7112  O O   . THR C 1 208 ? 113.907 94.988  158.129 1.00 33.33  ? 208 THR C O   1 
ATOM   7113  C CB  . THR C 1 208 ? 112.224 93.475  160.443 1.00 33.33  ? 208 THR C CB  1 
ATOM   7114  O OG1 . THR C 1 208 ? 111.034 93.576  159.654 1.00 33.33  ? 208 THR C OG1 1 
ATOM   7115  C CG2 . THR C 1 208 ? 112.487 94.803  161.118 1.00 33.33  ? 208 THR C CG2 1 
ATOM   7116  N N   . CYS C 1 209 ? 112.570 93.386  157.286 1.00 35.44  ? 209 CYS C N   1 
ATOM   7117  C CA  . CYS C 1 209 ? 112.522 93.984  155.959 1.00 35.44  ? 209 CYS C CA  1 
ATOM   7118  C C   . CYS C 1 209 ? 111.260 93.515  155.255 1.00 35.44  ? 209 CYS C C   1 
ATOM   7119  O O   . CYS C 1 209 ? 110.999 92.311  155.187 1.00 35.44  ? 209 CYS C O   1 
ATOM   7120  C CB  . CYS C 1 209 ? 113.774 93.608  155.160 1.00 35.44  ? 209 CYS C CB  1 
ATOM   7121  S SG  . CYS C 1 209 ? 113.909 94.282  153.494 1.00 35.44  ? 209 CYS C SG  1 
ATOM   7122  N N   . ILE C 1 210 ? 110.486 94.463  154.735 1.00 34.92  ? 210 ILE C N   1 
ATOM   7123  C CA  . ILE C 1 210 ? 109.195 94.194  154.113 1.00 34.92  ? 210 ILE C CA  1 
ATOM   7124  C C   . ILE C 1 210 ? 109.256 94.667  152.669 1.00 34.92  ? 210 ILE C C   1 
ATOM   7125  O O   . ILE C 1 210 ? 109.737 95.772  152.394 1.00 34.92  ? 210 ILE C O   1 
ATOM   7126  C CB  . ILE C 1 210 ? 108.051 94.882  154.877 1.00 34.92  ? 210 ILE C CB  1 
ATOM   7127  C CG1 . ILE C 1 210 ? 107.539 93.967  155.985 1.00 34.92  ? 210 ILE C CG1 1 
ATOM   7128  C CG2 . ILE C 1 210 ? 106.928 95.254  153.946 1.00 34.92  ? 210 ILE C CG2 1 
ATOM   7129  C CD1 . ILE C 1 210 ? 106.659 92.851  155.486 1.00 34.92  ? 210 ILE C CD1 1 
ATOM   7130  N N   . GLU C 1 211 ? 108.774 93.833  151.751 1.00 39.00  ? 211 GLU C N   1 
ATOM   7131  C CA  . GLU C 1 211 ? 108.971 94.038  150.324 1.00 39.00  ? 211 GLU C CA  1 
ATOM   7132  C C   . GLU C 1 211 ? 107.638 94.008  149.591 1.00 39.00  ? 211 GLU C C   1 
ATOM   7133  O O   . GLU C 1 211 ? 106.758 93.209  149.919 1.00 39.00  ? 211 GLU C O   1 
ATOM   7134  C CB  . GLU C 1 211 ? 109.903 92.963  149.764 1.00 39.00  ? 211 GLU C CB  1 
ATOM   7135  C CG  . GLU C 1 211 ? 110.227 93.090  148.297 1.00 39.00  ? 211 GLU C CG  1 
ATOM   7136  C CD  . GLU C 1 211 ? 111.230 92.048  147.849 1.00 39.00  ? 211 GLU C CD  1 
ATOM   7137  O OE1 . GLU C 1 211 ? 112.188 91.784  148.603 1.00 39.00  ? 211 GLU C OE1 1 
ATOM   7138  O OE2 . GLU C 1 211 ? 111.058 91.489  146.746 1.00 39.00  ? 211 GLU C OE2 1 
ATOM   7139  N N   . VAL C 1 212 ? 107.495 94.886  148.599 1.00 36.29  ? 212 VAL C N   1 
ATOM   7140  C CA  . VAL C 1 212 ? 106.339 94.907  147.710 1.00 36.29  ? 212 VAL C CA  1 
ATOM   7141  C C   . VAL C 1 212 ? 106.835 95.070  146.279 1.00 36.29  ? 212 VAL C C   1 
ATOM   7142  O O   . VAL C 1 212 ? 107.797 95.804  146.026 1.00 36.29  ? 212 VAL C O   1 
ATOM   7143  C CB  . VAL C 1 212 ? 105.343 96.025  148.087 1.00 36.29  ? 212 VAL C CB  1 
ATOM   7144  C CG1 . VAL C 1 212 ? 105.957 97.392  147.879 1.00 36.29  ? 212 VAL C CG1 1 
ATOM   7145  C CG2 . VAL C 1 212 ? 104.066 95.894  147.281 1.00 36.29  ? 212 VAL C CG2 1 
ATOM   7146  N N   . ARG C 1 213 ? 106.198 94.366  145.347 1.00 37.78  ? 213 ARG C N   1 
ATOM   7147  C CA  . ARG C 1 213 ? 106.610 94.357  143.950 1.00 37.78  ? 213 ARG C CA  1 
ATOM   7148  C C   . ARG C 1 213 ? 105.470 94.853  143.074 1.00 37.78  ? 213 ARG C C   1 
ATOM   7149  O O   . ARG C 1 213 ? 104.327 94.413  143.230 1.00 37.78  ? 213 ARG C O   1 
ATOM   7150  C CB  . ARG C 1 213 ? 107.034 92.955  143.508 1.00 37.78  ? 213 ARG C CB  1 
ATOM   7151  C CG  . ARG C 1 213 ? 107.647 92.116  144.612 1.00 37.78  ? 213 ARG C CG  1 
ATOM   7152  C CD  . ARG C 1 213 ? 107.915 90.696  144.145 1.00 37.78  ? 213 ARG C CD  1 
ATOM   7153  N NE  . ARG C 1 213 ? 108.924 90.653  143.096 1.00 37.78  ? 213 ARG C NE  1 
ATOM   7154  C CZ  . ARG C 1 213 ? 110.230 90.714  143.313 1.00 37.78  ? 213 ARG C CZ  1 
ATOM   7155  N NH1 . ARG C 1 213 ? 110.722 90.823  144.536 1.00 37.78  ? 213 ARG C NH1 1 
ATOM   7156  N NH2 . ARG C 1 213 ? 111.063 90.667  142.278 1.00 37.78  ? 213 ARG C NH2 1 
ATOM   7157  N N   . PHE C 1 214 ? 105.785 95.757  142.152 1.00 39.23  ? 214 PHE C N   1 
ATOM   7158  C CA  . PHE C 1 214 ? 104.824 96.287  141.195 1.00 39.23  ? 214 PHE C CA  1 
ATOM   7159  C C   . PHE C 1 214 ? 105.155 95.755  139.810 1.00 39.23  ? 214 PHE C C   1 
ATOM   7160  O O   . PHE C 1 214 ? 106.300 95.864  139.359 1.00 39.23  ? 214 PHE C O   1 
ATOM   7161  C CB  . PHE C 1 214 ? 104.843 97.816  141.183 1.00 39.23  ? 214 PHE C CB  1 
ATOM   7162  C CG  . PHE C 1 214 ? 104.471 98.437  142.493 1.00 39.23  ? 214 PHE C CG  1 
ATOM   7163  C CD1 . PHE C 1 214 ? 103.511 97.858  143.300 1.00 39.23  ? 214 PHE C CD1 1 
ATOM   7164  C CD2 . PHE C 1 214 ? 105.084 99.600  142.919 1.00 39.23  ? 214 PHE C CD2 1 
ATOM   7165  C CE1 . PHE C 1 214 ? 103.169 98.429  144.509 1.00 39.23  ? 214 PHE C CE1 1 
ATOM   7166  C CE2 . PHE C 1 214 ? 104.746 100.174 144.126 1.00 39.23  ? 214 PHE C CE2 1 
ATOM   7167  C CZ  . PHE C 1 214 ? 103.789 99.587  144.922 1.00 39.23  ? 214 PHE C CZ  1 
ATOM   7168  N N   . HIS C 1 215 ? 104.160 95.188  139.137 1.00 45.34  ? 215 HIS C N   1 
ATOM   7169  C CA  . HIS C 1 215 ? 104.340 94.667  137.788 1.00 45.34  ? 215 HIS C CA  1 
ATOM   7170  C C   . HIS C 1 215 ? 103.951 95.744  136.783 1.00 45.34  ? 215 HIS C C   1 
ATOM   7171  O O   . HIS C 1 215 ? 102.823 96.245  136.809 1.00 45.34  ? 215 HIS C O   1 
ATOM   7172  C CB  . HIS C 1 215 ? 103.505 93.407  137.577 1.00 45.34  ? 215 HIS C CB  1 
ATOM   7173  C CG  . HIS C 1 215 ? 103.894 92.267  138.466 1.00 45.34  ? 215 HIS C CG  1 
ATOM   7174  N ND1 . HIS C 1 215 ? 105.056 91.548  138.288 1.00 45.34  ? 215 HIS C ND1 1 
ATOM   7175  C CD2 . HIS C 1 215 ? 103.271 91.717  139.534 1.00 45.34  ? 215 HIS C CD2 1 
ATOM   7176  C CE1 . HIS C 1 215 ? 105.134 90.607  139.212 1.00 45.34  ? 215 HIS C CE1 1 
ATOM   7177  N NE2 . HIS C 1 215 ? 104.063 90.688  139.981 1.00 45.34  ? 215 HIS C NE2 1 
ATOM   7178  N N   . LEU C 1 216 ? 104.882 96.095  135.900 1.00 49.66  ? 216 LEU C N   1 
ATOM   7179  C CA  . LEU C 1 216 ? 104.665 97.134  134.904 1.00 49.66  ? 216 LEU C CA  1 
ATOM   7180  C C   . LEU C 1 216 ? 104.951 96.589  133.514 1.00 49.66  ? 216 LEU C C   1 
ATOM   7181  O O   . LEU C 1 216 ? 105.929 95.863  133.311 1.00 49.66  ? 216 LEU C O   1 
ATOM   7182  C CB  . LEU C 1 216 ? 105.552 98.353  135.169 1.00 49.66  ? 216 LEU C CB  1 
ATOM   7183  C CG  . LEU C 1 216 ? 105.257 99.137  136.445 1.00 49.66  ? 216 LEU C CG  1 
ATOM   7184  C CD1 . LEU C 1 216 ? 106.342 100.164 136.697 1.00 49.66  ? 216 LEU C CD1 1 
ATOM   7185  C CD2 . LEU C 1 216 ? 103.899 99.803  136.348 1.00 49.66  ? 216 LEU C CD2 1 
ATOM   7186  N N   . GLU C 1 217 ? 104.097 96.947  132.559 1.00 55.31  ? 217 GLU C N   1 
ATOM   7187  C CA  . GLU C 1 217 ? 104.297 96.607  131.160 1.00 55.31  ? 217 GLU C CA  1 
ATOM   7188  C C   . GLU C 1 217 ? 104.204 97.873  130.323 1.00 55.31  ? 217 GLU C C   1 
ATOM   7189  O O   . GLU C 1 217 ? 103.503 98.823  130.682 1.00 55.31  ? 217 GLU C O   1 
ATOM   7190  C CB  . GLU C 1 217 ? 103.276 95.572  130.674 1.00 55.31  ? 217 GLU C CB  1 
ATOM   7191  C CG  . GLU C 1 217 ? 101.831 96.011  130.793 1.00 55.31  ? 217 GLU C CG  1 
ATOM   7192  C CD  . GLU C 1 217 ? 100.868 94.977  130.244 1.00 55.31  ? 217 GLU C CD  1 
ATOM   7193  O OE1 . GLU C 1 217 ? 100.702 94.916  129.008 1.00 55.31  ? 217 GLU C OE1 1 
ATOM   7194  O OE2 . GLU C 1 217 ? 100.277 94.224  131.047 1.00 55.31  ? 217 GLU C OE2 1 
ATOM   7195  N N   . ARG C 1 218 ? 104.921 97.880  129.205 1.00 51.47  ? 218 ARG C N   1 
ATOM   7196  C CA  . ARG C 1 218 ? 105.043 99.062  128.364 1.00 51.47  ? 218 ARG C CA  1 
ATOM   7197  C C   . ARG C 1 218 ? 104.020 99.009  127.239 1.00 51.47  ? 218 ARG C C   1 
ATOM   7198  O O   . ARG C 1 218 ? 103.872 97.977  126.577 1.00 51.47  ? 218 ARG C O   1 
ATOM   7199  C CB  . ARG C 1 218 ? 106.455 99.173  127.788 1.00 51.47  ? 218 ARG C CB  1 
ATOM   7200  C CG  . ARG C 1 218 ? 106.763 100.520 127.169 1.00 51.47  ? 218 ARG C CG  1 
ATOM   7201  C CD  . ARG C 1 218 ? 108.173 100.555 126.619 1.00 51.47  ? 218 ARG C CD  1 
ATOM   7202  N NE  . ARG C 1 218 ? 109.131 99.959  127.541 1.00 51.47  ? 218 ARG C NE  1 
ATOM   7203  C CZ  . ARG C 1 218 ? 109.949 100.650 128.322 1.00 51.47  ? 218 ARG C CZ  1 
ATOM   7204  N NH1 . ARG C 1 218 ? 109.952 101.973 128.319 1.00 51.47  ? 218 ARG C NH1 1 
ATOM   7205  N NH2 . ARG C 1 218 ? 110.786 99.999  129.122 1.00 51.47  ? 218 ARG C NH2 1 
ATOM   7206  N N   . GLN C 1 219 ? 103.316 100.117 127.032 1.00 63.42  ? 219 GLN C N   1 
ATOM   7207  C CA  . GLN C 1 219 ? 102.330 100.187 125.964 1.00 63.42  ? 219 GLN C CA  1 
ATOM   7208  C C   . GLN C 1 219 ? 103.016 100.246 124.606 1.00 63.42  ? 219 GLN C C   1 
ATOM   7209  O O   . GLN C 1 219 ? 104.001 100.965 124.419 1.00 63.42  ? 219 GLN C O   1 
ATOM   7210  C CB  . GLN C 1 219 ? 101.427 101.403 126.153 1.00 63.42  ? 219 GLN C CB  1 
ATOM   7211  C CG  . GLN C 1 219 ? 100.564 101.326 127.394 1.00 63.42  ? 219 GLN C CG  1 
ATOM   7212  C CD  . GLN C 1 219 ? 99.185  101.908 127.177 1.00 63.42  ? 219 GLN C CD  1 
ATOM   7213  O OE1 . GLN C 1 219 ? 98.179  101.214 127.312 1.00 63.42  ? 219 GLN C OE1 1 
ATOM   7214  N NE2 . GLN C 1 219 ? 99.130  103.192 126.844 1.00 63.42  ? 219 GLN C NE2 1 
ATOM   7215  N N   . MET C 1 220 ? 102.485 99.487  123.653 1.00 64.15  ? 220 MET C N   1 
ATOM   7216  C CA  . MET C 1 220 ? 103.084 99.371  122.333 1.00 64.15  ? 220 MET C CA  1 
ATOM   7217  C C   . MET C 1 220 ? 102.605 100.427 121.347 1.00 64.15  ? 220 MET C C   1 
ATOM   7218  O O   . MET C 1 220 ? 103.152 100.504 120.243 1.00 64.15  ? 220 MET C O   1 
ATOM   7219  C CB  . MET C 1 220 ? 102.805 97.978  121.751 1.00 64.15  ? 220 MET C CB  1 
ATOM   7220  C CG  . MET C 1 220 ? 103.840 96.915  122.097 1.00 64.15  ? 220 MET C CG  1 
ATOM   7221  S SD  . MET C 1 220 ? 105.563 97.275  121.677 1.00 64.15  ? 220 MET C SD  1 
ATOM   7222  C CE  . MET C 1 220 ? 105.428 98.257  120.181 1.00 64.15  ? 220 MET C CE  1 
ATOM   7223  N N   . GLY C 1 221 ? 101.615 101.242 121.709 1.00 61.49  ? 221 GLY C N   1 
ATOM   7224  C CA  . GLY C 1 221 ? 101.025 102.143 120.731 1.00 61.49  ? 221 GLY C CA  1 
ATOM   7225  C C   . GLY C 1 221 ? 102.002 103.179 120.209 1.00 61.49  ? 221 GLY C C   1 
ATOM   7226  O O   . GLY C 1 221 ? 102.116 103.390 118.997 1.00 61.49  ? 221 GLY C O   1 
ATOM   7227  N N   . TYR C 1 222 ? 102.736 103.828 121.115 1.00 62.33  ? 222 TYR C N   1 
ATOM   7228  C CA  . TYR C 1 222 ? 103.584 104.942 120.706 1.00 62.33  ? 222 TYR C CA  1 
ATOM   7229  C C   . TYR C 1 222 ? 104.708 104.478 119.792 1.00 62.33  ? 222 TYR C C   1 
ATOM   7230  O O   . TYR C 1 222 ? 104.913 105.042 118.713 1.00 62.33  ? 222 TYR C O   1 
ATOM   7231  C CB  . TYR C 1 222 ? 104.164 105.655 121.924 1.00 62.33  ? 222 TYR C CB  1 
ATOM   7232  C CG  . TYR C 1 222 ? 105.383 106.481 121.584 1.00 62.33  ? 222 TYR C CG  1 
ATOM   7233  C CD1 . TYR C 1 222 ? 105.273 107.630 120.816 1.00 62.33  ? 222 TYR C CD1 1 
ATOM   7234  C CD2 . TYR C 1 222 ? 106.645 106.104 122.019 1.00 62.33  ? 222 TYR C CD2 1 
ATOM   7235  C CE1 . TYR C 1 222 ? 106.383 108.386 120.498 1.00 62.33  ? 222 TYR C CE1 1 
ATOM   7236  C CE2 . TYR C 1 222 ? 107.760 106.853 121.706 1.00 62.33  ? 222 TYR C CE2 1 
ATOM   7237  C CZ  . TYR C 1 222 ? 107.623 107.993 120.946 1.00 62.33  ? 222 TYR C CZ  1 
ATOM   7238  O OH  . TYR C 1 222 ? 108.732 108.742 120.633 1.00 62.33  ? 222 TYR C OH  1 
ATOM   7239  N N   . TYR C 1 223 ? 105.458 103.457 120.213 1.00 62.89  ? 223 TYR C N   1 
ATOM   7240  C CA  . TYR C 1 223 ? 106.596 103.006 119.418 1.00 62.89  ? 223 TYR C CA  1 
ATOM   7241  C C   . TYR C 1 223 ? 106.144 102.467 118.069 1.00 62.89  ? 223 TYR C C   1 
ATOM   7242  O O   . TYR C 1 223 ? 106.755 102.767 117.032 1.00 62.89  ? 223 TYR C O   1 
ATOM   7243  C CB  . TYR C 1 223 ? 107.388 101.950 120.188 1.00 62.89  ? 223 TYR C CB  1 
ATOM   7244  C CG  . TYR C 1 223 ? 108.319 102.546 121.211 1.00 62.89  ? 223 TYR C CG  1 
ATOM   7245  C CD1 . TYR C 1 223 ? 109.598 102.947 120.860 1.00 62.89  ? 223 TYR C CD1 1 
ATOM   7246  C CD2 . TYR C 1 223 ? 107.915 102.723 122.525 1.00 62.89  ? 223 TYR C CD2 1 
ATOM   7247  C CE1 . TYR C 1 223 ? 110.452 103.500 121.790 1.00 62.89  ? 223 TYR C CE1 1 
ATOM   7248  C CE2 . TYR C 1 223 ? 108.762 103.275 123.462 1.00 62.89  ? 223 TYR C CE2 1 
ATOM   7249  C CZ  . TYR C 1 223 ? 110.029 103.662 123.090 1.00 62.89  ? 223 TYR C CZ  1 
ATOM   7250  O OH  . TYR C 1 223 ? 110.877 104.215 124.022 1.00 62.89  ? 223 TYR C OH  1 
ATOM   7251  N N   . LEU C 1 224 ? 105.069 101.676 118.065 1.00 63.28  ? 224 LEU C N   1 
ATOM   7252  C CA  . LEU C 1 224 ? 104.512 101.176 116.816 1.00 63.28  ? 224 LEU C CA  1 
ATOM   7253  C C   . LEU C 1 224 ? 104.196 102.327 115.874 1.00 63.28  ? 224 LEU C C   1 
ATOM   7254  O O   . LEU C 1 224 ? 104.799 102.447 114.803 1.00 63.28  ? 224 LEU C O   1 
ATOM   7255  C CB  . LEU C 1 224 ? 103.261 100.340 117.092 1.00 63.28  ? 224 LEU C CB  1 
ATOM   7256  C CG  . LEU C 1 224 ? 102.556 99.757  115.867 1.00 63.28  ? 224 LEU C CG  1 
ATOM   7257  C CD1 . LEU C 1 224 ? 102.219 98.293  116.092 1.00 63.28  ? 224 LEU C CD1 1 
ATOM   7258  C CD2 . LEU C 1 224 ? 101.300 100.548 115.545 1.00 63.28  ? 224 LEU C CD2 1 
ATOM   7259  N N   . ILE C 1 225 ? 103.308 103.227 116.305 1.00 62.75  ? 225 ILE C N   1 
ATOM   7260  C CA  . ILE C 1 225 ? 102.856 104.316 115.443 1.00 62.75  ? 225 ILE C CA  1 
ATOM   7261  C C   . ILE C 1 225 ? 104.031 105.181 115.000 1.00 62.75  ? 225 ILE C C   1 
ATOM   7262  O O   . ILE C 1 225 ? 104.054 105.690 113.872 1.00 62.75  ? 225 ILE C O   1 
ATOM   7263  C CB  . ILE C 1 225 ? 101.771 105.134 116.170 1.00 62.75  ? 225 ILE C CB  1 
ATOM   7264  C CG1 . ILE C 1 225 ? 100.390 104.534 115.895 1.00 62.75  ? 225 ILE C CG1 1 
ATOM   7265  C CG2 . ILE C 1 225 ? 101.813 106.598 115.762 1.00 62.75  ? 225 ILE C CG2 1 
ATOM   7266  C CD1 . ILE C 1 225 ? 99.345  104.911 116.917 1.00 62.75  ? 225 ILE C CD1 1 
ATOM   7267  N N   . GLN C 1 226 ? 105.036 105.343 115.864 1.00 68.20  ? 226 GLN C N   1 
ATOM   7268  C CA  . GLN C 1 226 ? 106.129 106.256 115.551 1.00 68.20  ? 226 GLN C CA  1 
ATOM   7269  C C   . GLN C 1 226 ? 107.074 105.674 114.506 1.00 68.20  ? 226 GLN C C   1 
ATOM   7270  O O   . GLN C 1 226 ? 107.462 106.372 113.562 1.00 68.20  ? 226 GLN C O   1 
ATOM   7271  C CB  . GLN C 1 226 ? 106.892 106.616 116.825 1.00 68.20  ? 226 GLN C CB  1 
ATOM   7272  C CG  . GLN C 1 226 ? 107.621 107.949 116.747 1.00 68.20  ? 226 GLN C CG  1 
ATOM   7273  C CD  . GLN C 1 226 ? 108.937 107.861 116.003 1.00 68.20  ? 226 GLN C CD  1 
ATOM   7274  O OE1 . GLN C 1 226 ? 109.347 108.807 115.329 1.00 68.20  ? 226 GLN C OE1 1 
ATOM   7275  N NE2 . GLN C 1 226 ? 109.616 106.729 116.134 1.00 68.20  ? 226 GLN C NE2 1 
ATOM   7276  N N   . MET C 1 227 ? 107.471 104.405 114.649 1.00 74.23  ? 227 MET C N   1 
ATOM   7277  C CA  . MET C 1 227 ? 108.474 103.906 113.707 1.00 74.23  ? 227 MET C CA  1 
ATOM   7278  C C   . MET C 1 227 ? 108.129 102.605 112.987 1.00 74.23  ? 227 MET C C   1 
ATOM   7279  O O   . MET C 1 227 ? 108.602 102.388 111.867 1.00 74.23  ? 227 MET C O   1 
ATOM   7280  C CB  . MET C 1 227 ? 109.833 103.720 114.388 1.00 74.23  ? 227 MET C CB  1 
ATOM   7281  C CG  . MET C 1 227 ? 109.975 102.426 115.176 1.00 74.23  ? 227 MET C CG  1 
ATOM   7282  S SD  . MET C 1 227 ? 111.641 102.203 115.813 1.00 74.23  ? 227 MET C SD  1 
ATOM   7283  C CE  . MET C 1 227 ? 112.588 102.714 114.377 1.00 74.23  ? 227 MET C CE  1 
ATOM   7284  N N   . TYR C 1 228 ? 107.329 101.729 113.596 1.00 71.68  ? 228 TYR C N   1 
ATOM   7285  C CA  . TYR C 1 228 ? 107.160 100.396 113.025 1.00 71.68  ? 228 TYR C CA  1 
ATOM   7286  C C   . TYR C 1 228 ? 106.466 100.462 111.668 1.00 71.68  ? 228 TYR C C   1 
ATOM   7287  O O   . TYR C 1 228 ? 106.848 99.755  110.729 1.00 71.68  ? 228 TYR C O   1 
ATOM   7288  C CB  . TYR C 1 228 ? 106.386 99.500  113.992 1.00 71.68  ? 228 TYR C CB  1 
ATOM   7289  C CG  . TYR C 1 228 ? 107.267 98.709  114.937 1.00 71.68  ? 228 TYR C CG  1 
ATOM   7290  C CD1 . TYR C 1 228 ? 107.910 97.552  114.518 1.00 71.68  ? 228 TYR C CD1 1 
ATOM   7291  C CD2 . TYR C 1 228 ? 107.445 99.113  116.252 1.00 71.68  ? 228 TYR C CD2 1 
ATOM   7292  C CE1 . TYR C 1 228 ? 108.712 96.827  115.382 1.00 71.68  ? 228 TYR C CE1 1 
ATOM   7293  C CE2 . TYR C 1 228 ? 108.242 98.395  117.120 1.00 71.68  ? 228 TYR C CE2 1 
ATOM   7294  C CZ  . TYR C 1 228 ? 108.873 97.254  116.681 1.00 71.68  ? 228 TYR C CZ  1 
ATOM   7295  O OH  . TYR C 1 228 ? 109.667 96.539  117.546 1.00 71.68  ? 228 TYR C OH  1 
ATOM   7296  N N   . ILE C 1 229 ? 105.441 101.299 111.549 1.00 73.69  ? 229 ILE C N   1 
ATOM   7297  C CA  . ILE C 1 229 ? 104.743 101.510 110.282 1.00 73.69  ? 229 ILE C CA  1 
ATOM   7298  C C   . ILE C 1 229 ? 105.640 102.199 109.253 1.00 73.69  ? 229 ILE C C   1 
ATOM   7299  O O   . ILE C 1 229 ? 105.702 101.732 108.105 1.00 73.69  ? 229 ILE C O   1 
ATOM   7300  C CB  . ILE C 1 229 ? 103.434 102.289 110.503 1.00 73.69  ? 229 ILE C CB  1 
ATOM   7301  C CG1 . ILE C 1 229 ? 102.328 101.343 110.973 1.00 73.69  ? 229 ILE C CG1 1 
ATOM   7302  C CG2 . ILE C 1 229 ? 103.016 103.018 109.238 1.00 73.69  ? 229 ILE C CG2 1 
ATOM   7303  C CD1 . ILE C 1 229 ? 102.163 100.119 110.101 1.00 73.69  ? 229 ILE C CD1 1 
ATOM   7304  N N   . PRO C 1 230 ? 106.334 103.302 109.583 1.00 77.58  ? 230 PRO C N   1 
ATOM   7305  C CA  . PRO C 1 230 ? 107.164 103.958 108.555 1.00 77.58  ? 230 PRO C CA  1 
ATOM   7306  C C   . PRO C 1 230 ? 108.239 103.076 107.937 1.00 77.58  ? 230 PRO C C   1 
ATOM   7307  O O   . PRO C 1 230 ? 108.469 103.171 106.726 1.00 77.58  ? 230 PRO C O   1 
ATOM   7308  C CB  . PRO C 1 230 ? 107.772 105.147 109.310 1.00 77.58  ? 230 PRO C CB  1 
ATOM   7309  C CG  . PRO C 1 230 ? 106.778 105.457 110.350 1.00 77.58  ? 230 PRO C CG  1 
ATOM   7310  C CD  . PRO C 1 230 ? 106.243 104.136 110.797 1.00 77.58  ? 230 PRO C CD  1 
ATOM   7311  N N   . SER C 1 231 ? 108.910 102.225 108.716 1.00 74.39  ? 231 SER C N   1 
ATOM   7312  C CA  . SER C 1 231 ? 109.915 101.345 108.123 1.00 74.39  ? 231 SER C CA  1 
ATOM   7313  C C   . SER C 1 231 ? 109.274 100.358 107.155 1.00 74.39  ? 231 SER C C   1 
ATOM   7314  O O   . SER C 1 231 ? 109.819 100.082 106.077 1.00 74.39  ? 231 SER C O   1 
ATOM   7315  C CB  . SER C 1 231 ? 110.688 100.608 109.215 1.00 74.39  ? 231 SER C CB  1 
ATOM   7316  O OG  . SER C 1 231 ? 111.570 101.486 109.892 1.00 74.39  ? 231 SER C OG  1 
ATOM   7317  N N   . LEU C 1 232 ? 108.109 99.822  107.522 1.00 76.20  ? 232 LEU C N   1 
ATOM   7318  C CA  . LEU C 1 232 ? 107.386 98.931  106.624 1.00 76.20  ? 232 LEU C CA  1 
ATOM   7319  C C   . LEU C 1 232 ? 107.003 99.645  105.334 1.00 76.20  ? 232 LEU C C   1 
ATOM   7320  O O   . LEU C 1 232 ? 107.120 99.075  104.243 1.00 76.20  ? 232 LEU C O   1 
ATOM   7321  C CB  . LEU C 1 232 ? 106.146 98.381  107.327 1.00 76.20  ? 232 LEU C CB  1 
ATOM   7322  C CG  . LEU C 1 232 ? 105.396 97.249  106.626 1.00 76.20  ? 232 LEU C CG  1 
ATOM   7323  C CD1 . LEU C 1 232 ? 106.255 95.997  106.566 1.00 76.20  ? 232 LEU C CD1 1 
ATOM   7324  C CD2 . LEU C 1 232 ? 104.081 96.970  107.333 1.00 76.20  ? 232 LEU C CD2 1 
ATOM   7325  N N   . LEU C 1 233 ? 106.546 100.894 105.437 1.00 76.75  ? 233 LEU C N   1 
ATOM   7326  C CA  . LEU C 1 233 ? 106.190 101.644 104.236 1.00 76.75  ? 233 LEU C CA  1 
ATOM   7327  C C   . LEU C 1 233 ? 107.414 101.926 103.370 1.00 76.75  ? 233 LEU C C   1 
ATOM   7328  O O   . LEU C 1 233 ? 107.332 101.881 102.137 1.00 76.75  ? 233 LEU C O   1 
ATOM   7329  C CB  . LEU C 1 233 ? 105.483 102.943 104.617 1.00 76.75  ? 233 LEU C CB  1 
ATOM   7330  C CG  . LEU C 1 233 ? 104.195 102.762 105.420 1.00 76.75  ? 233 LEU C CG  1 
ATOM   7331  C CD1 . LEU C 1 233 ? 103.440 104.076 105.536 1.00 76.75  ? 233 LEU C CD1 1 
ATOM   7332  C CD2 . LEU C 1 233 ? 103.319 101.689 104.794 1.00 76.75  ? 233 LEU C CD2 1 
ATOM   7333  N N   . ILE C 1 234 ? 108.557 102.217 103.994 1.00 77.89  ? 234 ILE C N   1 
ATOM   7334  C CA  . ILE C 1 234 ? 109.785 102.439 103.232 1.00 77.89  ? 234 ILE C CA  1 
ATOM   7335  C C   . ILE C 1 234 ? 110.177 101.173 102.479 1.00 77.89  ? 234 ILE C C   1 
ATOM   7336  O O   . ILE C 1 234 ? 110.575 101.218 101.305 1.00 77.89  ? 234 ILE C O   1 
ATOM   7337  C CB  . ILE C 1 234 ? 110.914 102.917 104.167 1.00 77.89  ? 234 ILE C CB  1 
ATOM   7338  C CG1 . ILE C 1 234 ? 110.603 104.302 104.746 1.00 77.89  ? 234 ILE C CG1 1 
ATOM   7339  C CG2 . ILE C 1 234 ? 112.250 102.927 103.440 1.00 77.89  ? 234 ILE C CG2 1 
ATOM   7340  C CD1 . ILE C 1 234 ? 109.778 105.198 103.843 1.00 77.89  ? 234 ILE C CD1 1 
ATOM   7341  N N   . VAL C 1 235 ? 110.071 100.022 103.142 1.00 80.96  ? 235 VAL C N   1 
ATOM   7342  C CA  . VAL C 1 235 ? 110.397 98.764  102.480 1.00 80.96  ? 235 VAL C CA  1 
ATOM   7343  C C   . VAL C 1 235 ? 109.402 98.474  101.359 1.00 80.96  ? 235 VAL C C   1 
ATOM   7344  O O   . VAL C 1 235 ? 109.764 97.912  100.318 1.00 80.96  ? 235 VAL C O   1 
ATOM   7345  C CB  . VAL C 1 235 ? 110.459 97.626  103.513 1.00 80.96  ? 235 VAL C CB  1 
ATOM   7346  C CG1 . VAL C 1 235 ? 110.555 96.290  102.818 1.00 80.96  ? 235 VAL C CG1 1 
ATOM   7347  C CG2 . VAL C 1 235 ? 111.646 97.832  104.437 1.00 80.96  ? 235 VAL C CG2 1 
ATOM   7348  N N   . ILE C 1 236 ? 108.135 98.850  101.549 1.00 82.17  ? 236 ILE C N   1 
ATOM   7349  C CA  . ILE C 1 236 ? 107.151 98.728  100.474 1.00 82.17  ? 236 ILE C CA  1 
ATOM   7350  C C   . ILE C 1 236 ? 107.566 99.580  99.280  1.00 82.17  ? 236 ILE C C   1 
ATOM   7351  O O   . ILE C 1 236 ? 107.435 99.166  98.119  1.00 82.17  ? 236 ILE C O   1 
ATOM   7352  C CB  . ILE C 1 236 ? 105.752 99.113  100.990 1.00 82.17  ? 236 ILE C CB  1 
ATOM   7353  C CG1 . ILE C 1 236 ? 105.138 97.963  101.794 1.00 82.17  ? 236 ILE C CG1 1 
ATOM   7354  C CG2 . ILE C 1 236 ? 104.841 99.523  99.839  1.00 82.17  ? 236 ILE C CG2 1 
ATOM   7355  C CD1 . ILE C 1 236 ? 104.397 96.946  100.952 1.00 82.17  ? 236 ILE C CD1 1 
ATOM   7356  N N   . LEU C 1 237 ? 108.069 100.786 99.549  1.00 82.05  ? 237 LEU C N   1 
ATOM   7357  C CA  . LEU C 1 237 ? 108.566 101.640 98.473  1.00 82.05  ? 237 LEU C CA  1 
ATOM   7358  C C   . LEU C 1 237 ? 109.722 100.975 97.740  1.00 82.05  ? 237 LEU C C   1 
ATOM   7359  O O   . LEU C 1 237 ? 109.806 101.035 96.509  1.00 82.05  ? 237 LEU C O   1 
ATOM   7360  C CB  . LEU C 1 237 ? 108.996 102.998 99.026  1.00 82.05  ? 237 LEU C CB  1 
ATOM   7361  C CG  . LEU C 1 237 ? 107.927 103.863 99.697  1.00 82.05  ? 237 LEU C CG  1 
ATOM   7362  C CD1 . LEU C 1 237 ? 108.283 105.338 99.581  1.00 82.05  ? 237 LEU C CD1 1 
ATOM   7363  C CD2 . LEU C 1 237 ? 106.557 103.591 99.104  1.00 82.05  ? 237 LEU C CD2 1 
ATOM   7364  N N   . SER C 1 238 ? 110.626 100.334 98.483  1.00 87.72  ? 238 SER C N   1 
ATOM   7365  C CA  . SER C 1 238 ? 111.720 99.606  97.842  1.00 87.72  ? 238 SER C CA  1 
ATOM   7366  C C   . SER C 1 238 ? 111.190 98.470  96.970  1.00 87.72  ? 238 SER C C   1 
ATOM   7367  O O   . SER C 1 238 ? 111.677 98.247  95.852  1.00 87.72  ? 238 SER C O   1 
ATOM   7368  C CB  . SER C 1 238 ? 112.683 99.067  98.899  1.00 87.72  ? 238 SER C CB  1 
ATOM   7369  O OG  . SER C 1 238 ? 112.158 97.908  99.521  1.00 87.72  ? 238 SER C OG  1 
ATOM   7370  N N   . TRP C 1 239 ? 110.186 97.745  97.467  1.00 89.52  ? 239 TRP C N   1 
ATOM   7371  C CA  . TRP C 1 239 ? 109.583 96.666  96.690  1.00 89.52  ? 239 TRP C CA  1 
ATOM   7372  C C   . TRP C 1 239 ? 109.019 97.191  95.379  1.00 89.52  ? 239 TRP C C   1 
ATOM   7373  O O   . TRP C 1 239 ? 109.211 96.586  94.318  1.00 89.52  ? 239 TRP C O   1 
ATOM   7374  C CB  . TRP C 1 239 ? 108.481 95.983  97.498  1.00 89.52  ? 239 TRP C CB  1 
ATOM   7375  C CG  . TRP C 1 239 ? 108.961 95.258  98.703  1.00 89.52  ? 239 TRP C CG  1 
ATOM   7376  C CD1 . TRP C 1 239 ? 110.254 95.040  99.073  1.00 89.52  ? 239 TRP C CD1 1 
ATOM   7377  C CD2 . TRP C 1 239 ? 108.147 94.660  99.713  1.00 89.52  ? 239 TRP C CD2 1 
ATOM   7378  N NE1 . TRP C 1 239 ? 110.295 94.333  100.249 1.00 89.52  ? 239 TRP C NE1 1 
ATOM   7379  C CE2 . TRP C 1 239 ? 109.012 94.090  100.663 1.00 89.52  ? 239 TRP C CE2 1 
ATOM   7380  C CE3 . TRP C 1 239 ? 106.767 94.547  99.904  1.00 89.52  ? 239 TRP C CE3 1 
ATOM   7381  C CZ2 . TRP C 1 239 ? 108.544 93.422  101.788 1.00 89.52  ? 239 TRP C CZ2 1 
ATOM   7382  C CZ3 . TRP C 1 239 ? 106.304 93.881  101.021 1.00 89.52  ? 239 TRP C CZ3 1 
ATOM   7383  C CH2 . TRP C 1 239 ? 107.190 93.326  101.949 1.00 89.52  ? 239 TRP C CH2 1 
ATOM   7384  N N   . VAL C 1 240 ? 108.313 98.321  95.436  1.00 89.49  ? 240 VAL C N   1 
ATOM   7385  C CA  . VAL C 1 240 ? 107.812 98.936  94.210  1.00 89.49  ? 240 VAL C CA  1 
ATOM   7386  C C   . VAL C 1 240 ? 108.971 99.340  93.309  1.00 89.49  ? 240 VAL C C   1 
ATOM   7387  O O   . VAL C 1 240 ? 108.894 99.207  92.082  1.00 89.49  ? 240 VAL C O   1 
ATOM   7388  C CB  . VAL C 1 240 ? 106.902 100.136 94.540  1.00 89.49  ? 240 VAL C CB  1 
ATOM   7389  C CG1 . VAL C 1 240 ? 106.396 100.788 93.263  1.00 89.49  ? 240 VAL C CG1 1 
ATOM   7390  C CG2 . VAL C 1 240 ? 105.738 99.692  95.410  1.00 89.49  ? 240 VAL C CG2 1 
ATOM   7391  N N   . SER C 1 241 ? 110.066 99.822  93.900  1.00 95.08  ? 241 SER C N   1 
ATOM   7392  C CA  . SER C 1 241 ? 111.256 100.181 93.138  1.00 95.08  ? 241 SER C CA  1 
ATOM   7393  C C   . SER C 1 241 ? 111.941 98.978  92.505  1.00 95.08  ? 241 SER C C   1 
ATOM   7394  O O   . SER C 1 241 ? 112.803 99.166  91.640  1.00 95.08  ? 241 SER C O   1 
ATOM   7395  C CB  . SER C 1 241 ? 112.249 100.924 94.033  1.00 95.08  ? 241 SER C CB  1 
ATOM   7396  O OG  . SER C 1 241 ? 113.466 101.167 93.350  1.00 95.08  ? 241 SER C OG  1 
ATOM   7397  N N   . PHE C 1 242 ? 111.599 97.758  92.916  1.00 99.88  ? 242 PHE C N   1 
ATOM   7398  C CA  . PHE C 1 242 ? 112.126 96.579  92.232  1.00 99.88  ? 242 PHE C CA  1 
ATOM   7399  C C   . PHE C 1 242 ? 111.454 96.310  90.890  1.00 99.88  ? 242 PHE C C   1 
ATOM   7400  O O   . PHE C 1 242 ? 111.868 95.381  90.188  1.00 99.88  ? 242 PHE C O   1 
ATOM   7401  C CB  . PHE C 1 242 ? 112.001 95.335  93.115  1.00 99.88  ? 242 PHE C CB  1 
ATOM   7402  C CG  . PHE C 1 242 ? 112.760 95.429  94.402  1.00 99.88  ? 242 PHE C CG  1 
ATOM   7403  C CD1 . PHE C 1 242 ? 113.989 96.065  94.449  1.00 99.88  ? 242 PHE C CD1 1 
ATOM   7404  C CD2 . PHE C 1 242 ? 112.257 94.862  95.560  1.00 99.88  ? 242 PHE C CD2 1 
ATOM   7405  C CE1 . PHE C 1 242 ? 114.694 96.151  95.632  1.00 99.88  ? 242 PHE C CE1 1 
ATOM   7406  C CE2 . PHE C 1 242 ? 112.955 94.946  96.747  1.00 99.88  ? 242 PHE C CE2 1 
ATOM   7407  C CZ  . PHE C 1 242 ? 114.177 95.589  96.783  1.00 99.88  ? 242 PHE C CZ  1 
ATOM   7408  N N   . TRP C 1 243 ? 110.434 97.081  90.518  1.00 98.65  ? 243 TRP C N   1 
ATOM   7409  C CA  . TRP C 1 243 ? 109.742 96.909  89.248  1.00 98.65  ? 243 TRP C CA  1 
ATOM   7410  C C   . TRP C 1 243 ? 110.233 97.870  88.169  1.00 98.65  ? 243 TRP C C   1 
ATOM   7411  O O   . TRP C 1 243 ? 109.598 97.976  87.115  1.00 98.65  ? 243 TRP C O   1 
ATOM   7412  C CB  . TRP C 1 243 ? 108.233 97.072  89.440  1.00 98.65  ? 243 TRP C CB  1 
ATOM   7413  C CG  . TRP C 1 243 ? 107.589 95.922  90.149  1.00 98.65  ? 243 TRP C CG  1 
ATOM   7414  C CD1 . TRP C 1 243 ? 108.215 94.837  90.687  1.00 98.65  ? 243 TRP C CD1 1 
ATOM   7415  C CD2 . TRP C 1 243 ? 106.188 95.736  90.387  1.00 98.65  ? 243 TRP C CD2 1 
ATOM   7416  N NE1 . TRP C 1 243 ? 107.293 93.988  91.250  1.00 98.65  ? 243 TRP C NE1 1 
ATOM   7417  C CE2 . TRP C 1 243 ? 106.041 94.517  91.079  1.00 98.65  ? 243 TRP C CE2 1 
ATOM   7418  C CE3 . TRP C 1 243 ? 105.045 96.482  90.085  1.00 98.65  ? 243 TRP C CE3 1 
ATOM   7419  C CZ2 . TRP C 1 243 ? 104.798 94.028  91.473  1.00 98.65  ? 243 TRP C CZ2 1 
ATOM   7420  C CZ3 . TRP C 1 243 ? 103.811 95.994  90.478  1.00 98.65  ? 243 TRP C CZ3 1 
ATOM   7421  C CH2 . TRP C 1 243 ? 103.698 94.779  91.164  1.00 98.65  ? 243 TRP C CH2 1 
ATOM   7422  N N   . ILE C 1 244 ? 111.341 98.568  88.405  1.00 99.58  ? 244 ILE C N   1 
ATOM   7423  C CA  . ILE C 1 244 ? 111.859 99.540  87.452  1.00 99.58  ? 244 ILE C CA  1 
ATOM   7424  C C   . ILE C 1 244 ? 112.832 98.849  86.503  1.00 99.58  ? 244 ILE C C   1 
ATOM   7425  O O   . ILE C 1 244 ? 113.387 97.788  86.799  1.00 99.58  ? 244 ILE C O   1 
ATOM   7426  C CB  . ILE C 1 244 ? 112.522 100.731 88.176  1.00 99.58  ? 244 ILE C CB  1 
ATOM   7427  C CG1 . ILE C 1 244 ? 111.711 101.113 89.414  1.00 99.58  ? 244 ILE C CG1 1 
ATOM   7428  C CG2 . ILE C 1 244 ? 112.638 101.936 87.256  1.00 99.58  ? 244 ILE C CG2 1 
ATOM   7429  C CD1 . ILE C 1 244 ? 110.327 101.644 89.100  1.00 99.58  ? 244 ILE C CD1 1 
ATOM   7430  N N   . ASN C 1 245 ? 113.041 99.463  85.338  1.00 102.59 ? 245 ASN C N   1 
ATOM   7431  C CA  . ASN C 1 245 ? 113.881 98.915  84.278  1.00 102.59 ? 245 ASN C CA  1 
ATOM   7432  C C   . ASN C 1 245 ? 115.146 99.743  84.066  1.00 102.59 ? 245 ASN C C   1 
ATOM   7433  O O   . ASN C 1 245 ? 115.629 99.885  82.940  1.00 102.59 ? 245 ASN C O   1 
ATOM   7434  C CB  . ASN C 1 245 ? 113.097 98.815  82.972  1.00 102.59 ? 245 ASN C CB  1 
ATOM   7435  C CG  . ASN C 1 245 ? 112.664 100.171 82.449  1.00 102.59 ? 245 ASN C CG  1 
ATOM   7436  O OD1 . ASN C 1 245 ? 111.942 100.906 83.122  1.00 102.59 ? 245 ASN C OD1 1 
ATOM   7437  N ND2 . ASN C 1 245 ? 113.112 100.512 81.247  1.00 102.59 ? 245 ASN C ND2 1 
ATOM   7438  N N   . MET C 1 246 ? 115.696 100.296 85.150  1.00 111.24 ? 246 MET C N   1 
ATOM   7439  C CA  . MET C 1 246 ? 116.921 101.100 85.118  1.00 111.24 ? 246 MET C CA  1 
ATOM   7440  C C   . MET C 1 246 ? 116.750 102.297 84.176  1.00 111.24 ? 246 MET C C   1 
ATOM   7441  O O   . MET C 1 246 ? 117.365 102.396 83.112  1.00 111.24 ? 246 MET C O   1 
ATOM   7442  C CB  . MET C 1 246 ? 118.128 100.236 84.728  1.00 111.24 ? 246 MET C CB  1 
ATOM   7443  C CG  . MET C 1 246 ? 119.487 100.762 85.196  1.00 111.24 ? 246 MET C CG  1 
ATOM   7444  S SD  . MET C 1 246 ? 120.113 102.233 84.359  1.00 111.24 ? 246 MET C SD  1 
ATOM   7445  C CE  . MET C 1 246 ? 120.515 101.564 82.746  1.00 111.24 ? 246 MET C CE  1 
ATOM   7446  N N   . ASP C 1 247 ? 115.852 103.194 84.587  1.00 100.44 ? 247 ASP C N   1 
ATOM   7447  C CA  . ASP C 1 247 ? 115.571 104.381 83.786  1.00 100.44 ? 247 ASP C CA  1 
ATOM   7448  C C   . ASP C 1 247 ? 116.783 105.304 83.726  1.00 100.44 ? 247 ASP C C   1 
ATOM   7449  O O   . ASP C 1 247 ? 117.186 105.747 82.643  1.00 100.44 ? 247 ASP C O   1 
ATOM   7450  C CB  . ASP C 1 247 ? 114.357 105.118 84.353  1.00 100.44 ? 247 ASP C CB  1 
ATOM   7451  C CG  . ASP C 1 247 ? 113.051 104.421 84.030  1.00 100.44 ? 247 ASP C CG  1 
ATOM   7452  O OD1 . ASP C 1 247 ? 112.908 103.920 82.895  1.00 100.44 ? 247 ASP C OD1 1 
ATOM   7453  O OD2 . ASP C 1 247 ? 112.166 104.376 84.908  1.00 100.44 ? 247 ASP C OD2 1 
ATOM   7454  N N   . ALA C 1 248 ? 117.379 105.604 84.878  1.00 101.05 ? 248 ALA C N   1 
ATOM   7455  C CA  . ALA C 1 248 ? 118.571 106.434 84.950  1.00 101.05 ? 248 ALA C CA  1 
ATOM   7456  C C   . ALA C 1 248 ? 119.440 105.953 86.102  1.00 101.05 ? 248 ALA C C   1 
ATOM   7457  O O   . ALA C 1 248 ? 118.935 105.457 87.111  1.00 101.05 ? 248 ALA C O   1 
ATOM   7458  C CB  . ALA C 1 248 ? 118.221 107.917 85.133  1.00 101.05 ? 248 ALA C CB  1 
ATOM   7459  N N   . ALA C 1 249 ? 120.754 106.103 85.944  1.00 95.90  ? 249 ALA C N   1 
ATOM   7460  C CA  . ALA C 1 249 ? 121.691 105.615 86.950  1.00 95.90  ? 249 ALA C CA  1 
ATOM   7461  C C   . ALA C 1 249 ? 121.739 106.514 88.187  1.00 95.90  ? 249 ALA C C   1 
ATOM   7462  O O   . ALA C 1 249 ? 121.500 106.022 89.299  1.00 95.90  ? 249 ALA C O   1 
ATOM   7463  C CB  . ALA C 1 249 ? 123.088 105.445 86.345  1.00 95.90  ? 249 ALA C CB  1 
ATOM   7464  N N   . PRO C 1 250 ? 122.051 107.815 88.066  1.00 94.11  ? 250 PRO C N   1 
ATOM   7465  C CA  . PRO C 1 250 ? 122.149 108.629 89.291  1.00 94.11  ? 250 PRO C CA  1 
ATOM   7466  C C   . PRO C 1 250 ? 120.824 108.784 90.015  1.00 94.11  ? 250 PRO C C   1 
ATOM   7467  O O   . PRO C 1 250 ? 120.801 108.829 91.252  1.00 94.11  ? 250 PRO C O   1 
ATOM   7468  C CB  . PRO C 1 250 ? 122.684 109.970 88.774  1.00 94.11  ? 250 PRO C CB  1 
ATOM   7469  C CG  . PRO C 1 250 ? 122.171 110.054 87.394  1.00 94.11  ? 250 PRO C CG  1 
ATOM   7470  C CD  . PRO C 1 250 ? 122.216 108.650 86.859  1.00 94.11  ? 250 PRO C CD  1 
ATOM   7471  N N   . ALA C 1 251 ? 119.713 108.864 89.278  1.00 96.57  ? 251 ALA C N   1 
ATOM   7472  C CA  . ALA C 1 251 ? 118.406 108.948 89.922  1.00 96.57  ? 251 ALA C CA  1 
ATOM   7473  C C   . ALA C 1 251 ? 118.094 107.676 90.700  1.00 96.57  ? 251 ALA C C   1 
ATOM   7474  O O   . ALA C 1 251 ? 117.565 107.734 91.816  1.00 96.57  ? 251 ALA C O   1 
ATOM   7475  C CB  . ALA C 1 251 ? 117.322 109.221 88.879  1.00 96.57  ? 251 ALA C CB  1 
ATOM   7476  N N   . ARG C 1 252 ? 118.414 106.515 90.124  1.00 96.15  ? 252 ARG C N   1 
ATOM   7477  C CA  . ARG C 1 252 ? 118.215 105.253 90.828  1.00 96.15  ? 252 ARG C CA  1 
ATOM   7478  C C   . ARG C 1 252 ? 119.101 105.176 92.067  1.00 96.15  ? 252 ARG C C   1 
ATOM   7479  O O   . ARG C 1 252 ? 118.672 104.686 93.120  1.00 96.15  ? 252 ARG C O   1 
ATOM   7480  C CB  . ARG C 1 252 ? 118.493 104.091 89.875  1.00 96.15  ? 252 ARG C CB  1 
ATOM   7481  C CG  . ARG C 1 252 ? 118.095 102.715 90.368  1.00 96.15  ? 252 ARG C CG  1 
ATOM   7482  C CD  . ARG C 1 252 ? 118.007 101.768 89.179  1.00 96.15  ? 252 ARG C CD  1 
ATOM   7483  N NE  . ARG C 1 252 ? 117.604 100.417 89.548  1.00 96.15  ? 252 ARG C NE  1 
ATOM   7484  C CZ  . ARG C 1 252 ? 118.431 99.385  89.621  1.00 96.15  ? 252 ARG C CZ  1 
ATOM   7485  N NH1 . ARG C 1 252 ? 119.720 99.512  89.352  1.00 96.15  ? 252 ARG C NH1 1 
ATOM   7486  N NH2 . ARG C 1 252 ? 117.951 98.193  89.962  1.00 96.15  ? 252 ARG C NH2 1 
ATOM   7487  N N   . VAL C 1 253 ? 120.336 105.673 91.962  1.00 92.28  ? 253 VAL C N   1 
ATOM   7488  C CA  . VAL C 1 253 ? 121.231 105.706 93.117  1.00 92.28  ? 253 VAL C CA  1 
ATOM   7489  C C   . VAL C 1 253 ? 120.636 106.567 94.226  1.00 92.28  ? 253 VAL C C   1 
ATOM   7490  O O   . VAL C 1 253 ? 120.625 106.179 95.400  1.00 92.28  ? 253 VAL C O   1 
ATOM   7491  C CB  . VAL C 1 253 ? 122.625 106.207 92.698  1.00 92.28  ? 253 VAL C CB  1 
ATOM   7492  C CG1 . VAL C 1 253 ? 123.398 106.720 93.906  1.00 92.28  ? 253 VAL C CG1 1 
ATOM   7493  C CG2 . VAL C 1 253 ? 123.395 105.101 91.996  1.00 92.28  ? 253 VAL C CG2 1 
ATOM   7494  N N   . ALA C 1 254 ? 120.128 107.749 93.867  1.00 87.01  ? 254 ALA C N   1 
ATOM   7495  C CA  . ALA C 1 254 ? 119.534 108.632 94.867  1.00 87.01  ? 254 ALA C CA  1 
ATOM   7496  C C   . ALA C 1 254 ? 118.297 108.003 95.497  1.00 87.01  ? 254 ALA C C   1 
ATOM   7497  O O   . ALA C 1 254 ? 118.080 108.119 96.710  1.00 87.01  ? 254 ALA C O   1 
ATOM   7498  C CB  . ALA C 1 254 ? 119.189 109.981 94.237  1.00 87.01  ? 254 ALA C CB  1 
ATOM   7499  N N   . LEU C 1 255 ? 117.469 107.340 94.684  1.00 88.31  ? 255 LEU C N   1 
ATOM   7500  C CA  . LEU C 1 255 ? 116.289 106.666 95.214  1.00 88.31  ? 255 LEU C CA  1 
ATOM   7501  C C   . LEU C 1 255 ? 116.673 105.561 96.185  1.00 88.31  ? 255 LEU C C   1 
ATOM   7502  O O   . LEU C 1 255 ? 115.978 105.341 97.183  1.00 88.31  ? 255 LEU C O   1 
ATOM   7503  C CB  . LEU C 1 255 ? 115.446 106.099 94.071  1.00 88.31  ? 255 LEU C CB  1 
ATOM   7504  C CG  . LEU C 1 255 ? 114.203 106.890 93.654  1.00 88.31  ? 255 LEU C CG  1 
ATOM   7505  C CD1 . LEU C 1 255 ? 113.295 107.123 94.849  1.00 88.31  ? 255 LEU C CD1 1 
ATOM   7506  C CD2 . LEU C 1 255 ? 114.583 108.209 92.999  1.00 88.31  ? 255 LEU C CD2 1 
ATOM   7507  N N   . GLY C 1 256 ? 117.767 104.850 95.907  1.00 86.93  ? 256 GLY C N   1 
ATOM   7508  C CA  . GLY C 1 256 ? 118.257 103.871 96.863  1.00 86.93  ? 256 GLY C CA  1 
ATOM   7509  C C   . GLY C 1 256 ? 118.772 104.505 98.143  1.00 86.93  ? 256 GLY C C   1 
ATOM   7510  O O   . GLY C 1 256 ? 118.523 103.999 99.241  1.00 86.93  ? 256 GLY C O   1 
ATOM   7511  N N   . ILE C 1 257 ? 119.494 105.621 98.020  1.00 88.16  ? 257 ILE C N   1 
ATOM   7512  C CA  . ILE C 1 257 ? 120.114 106.249 99.188  1.00 88.16  ? 257 ILE C CA  1 
ATOM   7513  C C   . ILE C 1 257 ? 119.056 106.845 100.114 1.00 88.16  ? 257 ILE C C   1 
ATOM   7514  O O   . ILE C 1 257 ? 119.230 106.874 101.338 1.00 88.16  ? 257 ILE C O   1 
ATOM   7515  C CB  . ILE C 1 257 ? 121.147 107.304 98.749  1.00 88.16  ? 257 ILE C CB  1 
ATOM   7516  C CG1 . ILE C 1 257 ? 122.275 106.648 97.954  1.00 88.16  ? 257 ILE C CG1 1 
ATOM   7517  C CG2 . ILE C 1 257 ? 121.731 108.031 99.952  1.00 88.16  ? 257 ILE C CG2 1 
ATOM   7518  C CD1 . ILE C 1 257 ? 122.952 105.513 98.685  1.00 88.16  ? 257 ILE C CD1 1 
ATOM   7519  N N   . THR C 1 258 ? 117.960 107.359 99.547  1.00 90.36  ? 258 THR C N   1 
ATOM   7520  C CA  . THR C 1 258 ? 116.930 107.989 100.376 1.00 90.36  ? 258 THR C CA  1 
ATOM   7521  C C   . THR C 1 258 ? 116.321 107.006 101.370 1.00 90.36  ? 258 THR C C   1 
ATOM   7522  O O   . THR C 1 258 ? 116.113 107.340 102.547 1.00 90.36  ? 258 THR C O   1 
ATOM   7523  C CB  . THR C 1 258 ? 115.834 108.585 99.495  1.00 90.36  ? 258 THR C CB  1 
ATOM   7524  O OG1 . THR C 1 258 ? 115.360 107.592 98.577  1.00 90.36  ? 258 THR C OG1 1 
ATOM   7525  C CG2 . THR C 1 258 ? 116.368 109.767 98.727  1.00 90.36  ? 258 THR C CG2 1 
ATOM   7526  N N   . THR C 1 259 ? 116.005 105.795 100.907 1.00 90.58  ? 259 THR C N   1 
ATOM   7527  C CA  . THR C 1 259 ? 115.468 104.783 101.808 1.00 90.58  ? 259 THR C CA  1 
ATOM   7528  C C   . THR C 1 259 ? 116.481 104.429 102.885 1.00 90.58  ? 259 THR C C   1 
ATOM   7529  O O   . THR C 1 259 ? 116.117 104.238 104.052 1.00 90.58  ? 259 THR C O   1 
ATOM   7530  C CB  . THR C 1 259 ? 115.058 103.539 101.021 1.00 90.58  ? 259 THR C CB  1 
ATOM   7531  O OG1 . THR C 1 259 ? 116.176 103.065 100.260 1.00 90.58  ? 259 THR C OG1 1 
ATOM   7532  C CG2 . THR C 1 259 ? 113.908 103.863 100.078 1.00 90.58  ? 259 THR C CG2 1 
ATOM   7533  N N   . VAL C 1 260 ? 117.761 104.349 102.512 1.00 92.29  ? 260 VAL C N   1 
ATOM   7534  C CA  . VAL C 1 260 ? 118.814 104.101 103.491 1.00 92.29  ? 260 VAL C CA  1 
ATOM   7535  C C   . VAL C 1 260 ? 118.820 105.197 104.549 1.00 92.29  ? 260 VAL C C   1 
ATOM   7536  O O   . VAL C 1 260 ? 118.983 104.928 105.744 1.00 92.29  ? 260 VAL C O   1 
ATOM   7537  C CB  . VAL C 1 260 ? 120.180 103.989 102.787 1.00 92.29  ? 260 VAL C CB  1 
ATOM   7538  C CG1 . VAL C 1 260 ? 121.317 104.077 103.795 1.00 92.29  ? 260 VAL C CG1 1 
ATOM   7539  C CG2 . VAL C 1 260 ? 120.268 102.703 101.991 1.00 92.29  ? 260 VAL C CG2 1 
ATOM   7540  N N   . LEU C 1 261 ? 118.650 106.450 104.124 1.00 91.74  ? 261 LEU C N   1 
ATOM   7541  C CA  . LEU C 1 261 ? 118.688 107.570 105.060 1.00 91.74  ? 261 LEU C CA  1 
ATOM   7542  C C   . LEU C 1 261 ? 117.517 107.521 106.033 1.00 91.74  ? 261 LEU C C   1 
ATOM   7543  O O   . LEU C 1 261 ? 117.693 107.706 107.243 1.00 91.74  ? 261 LEU C O   1 
ATOM   7544  C CB  . LEU C 1 261 ? 118.695 108.892 104.295 1.00 91.74  ? 261 LEU C CB  1 
ATOM   7545  C CG  . LEU C 1 261 ? 119.973 109.188 103.513 1.00 91.74  ? 261 LEU C CG  1 
ATOM   7546  C CD1 . LEU C 1 261 ? 119.808 110.449 102.681 1.00 91.74  ? 261 LEU C CD1 1 
ATOM   7547  C CD2 . LEU C 1 261 ? 121.160 109.307 104.460 1.00 91.74  ? 261 LEU C CD2 1 
ATOM   7548  N N   . THR C 1 262 ? 116.309 107.286 105.520 1.00 86.35  ? 262 THR C N   1 
ATOM   7549  C CA  . THR C 1 262 ? 115.151 107.169 106.406 1.00 86.35  ? 262 THR C CA  1 
ATOM   7550  C C   . THR C 1 262 ? 115.339 106.015 107.387 1.00 86.35  ? 262 THR C C   1 
ATOM   7551  O O   . THR C 1 262 ? 115.107 106.154 108.599 1.00 86.35  ? 262 THR C O   1 
ATOM   7552  C CB  . THR C 1 262 ? 113.876 106.978 105.579 1.00 86.35  ? 262 THR C CB  1 
ATOM   7553  O OG1 . THR C 1 262 ? 113.957 105.748 104.849 1.00 86.35  ? 262 THR C OG1 1 
ATOM   7554  C CG2 . THR C 1 262 ? 113.689 108.133 104.600 1.00 86.35  ? 262 THR C CG2 1 
ATOM   7555  N N   . MET C 1 263 ? 115.791 104.873 106.869 1.00 86.58  ? 263 MET C N   1 
ATOM   7556  C CA  . MET C 1 263 ? 116.072 103.698 107.686 1.00 86.58  ? 263 MET C CA  1 
ATOM   7557  C C   . MET C 1 263 ? 117.045 104.021 108.812 1.00 86.58  ? 263 MET C C   1 
ATOM   7558  O O   . MET C 1 263 ? 116.780 103.720 109.984 1.00 86.58  ? 263 MET C O   1 
ATOM   7559  C CB  . MET C 1 263 ? 116.609 102.602 106.757 1.00 86.58  ? 263 MET C CB  1 
ATOM   7560  C CG  . MET C 1 263 ? 117.189 101.329 107.354 1.00 86.58  ? 263 MET C CG  1 
ATOM   7561  S SD  . MET C 1 263 ? 118.829 101.603 108.053 1.00 86.58  ? 263 MET C SD  1 
ATOM   7562  C CE  . MET C 1 263 ? 119.868 100.927 106.766 1.00 86.58  ? 263 MET C CE  1 
ATOM   7563  N N   . THR C 1 264 ? 118.179 104.639 108.475 1.00 87.98  ? 264 THR C N   1 
ATOM   7564  C CA  . THR C 1 264 ? 119.213 104.877 109.475 1.00 87.98  ? 264 THR C CA  1 
ATOM   7565  C C   . THR C 1 264 ? 118.801 105.952 110.469 1.00 87.98  ? 264 THR C C   1 
ATOM   7566  O O   . THR C 1 264 ? 119.151 105.855 111.648 1.00 87.98  ? 264 THR C O   1 
ATOM   7567  C CB  . THR C 1 264 ? 120.547 105.233 108.809 1.00 87.98  ? 264 THR C CB  1 
ATOM   7568  O OG1 . THR C 1 264 ? 121.572 105.292 109.810 1.00 87.98  ? 264 THR C OG1 1 
ATOM   7569  C CG2 . THR C 1 264 ? 120.480 106.571 108.083 1.00 87.98  ? 264 THR C CG2 1 
ATOM   7570  N N   . THR C 1 265 ? 118.052 106.970 110.035 1.00 86.36  ? 265 THR C N   1 
ATOM   7571  C CA  . THR C 1 265 ? 117.563 107.961 110.986 1.00 86.36  ? 265 THR C CA  1 
ATOM   7572  C C   . THR C 1 265 ? 116.657 107.310 112.019 1.00 86.36  ? 265 THR C C   1 
ATOM   7573  O O   . THR C 1 265 ? 116.829 107.508 113.229 1.00 86.36  ? 265 THR C O   1 
ATOM   7574  C CB  . THR C 1 265 ? 116.821 109.085 110.261 1.00 86.36  ? 265 THR C CB  1 
ATOM   7575  O OG1 . THR C 1 265 ? 115.907 108.524 109.311 1.00 86.36  ? 265 THR C OG1 1 
ATOM   7576  C CG2 . THR C 1 265 ? 117.799 110.005 109.547 1.00 86.36  ? 265 THR C CG2 1 
ATOM   7577  N N   . GLN C 1 266 ? 115.698 106.502 111.557 1.00 79.80  ? 266 GLN C N   1 
ATOM   7578  C CA  . GLN C 1 266 ? 114.792 105.850 112.498 1.00 79.80  ? 266 GLN C CA  1 
ATOM   7579  C C   . GLN C 1 266 ? 115.550 104.916 113.436 1.00 79.80  ? 266 GLN C C   1 
ATOM   7580  O O   . GLN C 1 266 ? 115.324 104.925 114.658 1.00 79.80  ? 266 GLN C O   1 
ATOM   7581  C CB  . GLN C 1 266 ? 113.707 105.095 111.731 1.00 79.80  ? 266 GLN C CB  1 
ATOM   7582  C CG  . GLN C 1 266 ? 112.856 105.989 110.842 1.00 79.80  ? 266 GLN C CG  1 
ATOM   7583  C CD  . GLN C 1 266 ? 111.417 105.529 110.753 1.00 79.80  ? 266 GLN C CD  1 
ATOM   7584  O OE1 . GLN C 1 266 ? 111.135 104.332 110.751 1.00 79.80  ? 266 GLN C OE1 1 
ATOM   7585  N NE2 . GLN C 1 266 ? 110.496 106.482 110.669 1.00 79.80  ? 266 GLN C NE2 1 
ATOM   7586  N N   . SER C 1 267 ? 116.471 104.118 112.887 1.00 86.47  ? 267 SER C N   1 
ATOM   7587  C CA  . SER C 1 267 ? 117.206 103.165 113.712 1.00 86.47  ? 267 SER C CA  1 
ATOM   7588  C C   . SER C 1 267 ? 118.072 103.875 114.744 1.00 86.47  ? 267 SER C C   1 
ATOM   7589  O O   . SER C 1 267 ? 118.106 103.476 115.914 1.00 86.47  ? 267 SER C O   1 
ATOM   7590  C CB  . SER C 1 267 ? 118.061 102.257 112.830 1.00 86.47  ? 267 SER C CB  1 
ATOM   7591  O OG  . SER C 1 267 ? 119.190 102.951 112.332 1.00 86.47  ? 267 SER C OG  1 
ATOM   7592  N N   . SER C 1 268 ? 118.777 104.931 114.333 1.00 86.56  ? 268 SER C N   1 
ATOM   7593  C CA  . SER C 1 268 ? 119.630 105.660 115.262 1.00 86.56  ? 268 SER C CA  1 
ATOM   7594  C C   . SER C 1 268 ? 118.809 106.326 116.356 1.00 86.56  ? 268 SER C C   1 
ATOM   7595  O O   . SER C 1 268 ? 119.203 106.311 117.527 1.00 86.56  ? 268 SER C O   1 
ATOM   7596  C CB  . SER C 1 268 ? 120.459 106.694 114.503 1.00 86.56  ? 268 SER C CB  1 
ATOM   7597  O OG  . SER C 1 268 ? 119.632 107.509 113.690 1.00 86.56  ? 268 SER C OG  1 
ATOM   7598  N N   . GLY C 1 269 ? 117.661 106.909 115.999 1.00 81.88  ? 269 GLY C N   1 
ATOM   7599  C CA  . GLY C 1 269 ? 116.826 107.526 117.016 1.00 81.88  ? 269 GLY C CA  1 
ATOM   7600  C C   . GLY C 1 269 ? 116.347 106.523 118.044 1.00 81.88  ? 269 GLY C C   1 
ATOM   7601  O O   . GLY C 1 269 ? 116.430 106.761 119.254 1.00 81.88  ? 269 GLY C O   1 
ATOM   7602  N N   . SER C 1 270 ? 115.846 105.378 117.578 1.00 84.99  ? 270 SER C N   1 
ATOM   7603  C CA  . SER C 1 270 ? 115.344 104.383 118.520 1.00 84.99  ? 270 SER C CA  1 
ATOM   7604  C C   . SER C 1 270 ? 116.467 103.799 119.369 1.00 84.99  ? 270 SER C C   1 
ATOM   7605  O O   . SER C 1 270 ? 116.281 103.548 120.566 1.00 84.99  ? 270 SER C O   1 
ATOM   7606  C CB  . SER C 1 270 ? 114.592 103.287 117.778 1.00 84.99  ? 270 SER C CB  1 
ATOM   7607  O OG  . SER C 1 270 ? 113.577 103.861 116.976 1.00 84.99  ? 270 SER C OG  1 
ATOM   7608  N N   . ARG C 1 271 ? 117.643 103.585 118.777 1.00 87.78  ? 271 ARG C N   1 
ATOM   7609  C CA  . ARG C 1 271 ? 118.761 103.067 119.559 1.00 87.78  ? 271 ARG C CA  1 
ATOM   7610  C C   . ARG C 1 271 ? 119.236 104.083 120.594 1.00 87.78  ? 271 ARG C C   1 
ATOM   7611  O O   . ARG C 1 271 ? 119.647 103.705 121.697 1.00 87.78  ? 271 ARG C O   1 
ATOM   7612  C CB  . ARG C 1 271 ? 119.909 102.653 118.637 1.00 87.78  ? 271 ARG C CB  1 
ATOM   7613  C CG  . ARG C 1 271 ? 119.632 101.414 117.792 1.00 87.78  ? 271 ARG C CG  1 
ATOM   7614  C CD  . ARG C 1 271 ? 120.609 101.320 116.627 1.00 87.78  ? 271 ARG C CD  1 
ATOM   7615  N NE  . ARG C 1 271 ? 120.128 100.435 115.573 1.00 87.78  ? 271 ARG C NE  1 
ATOM   7616  C CZ  . ARG C 1 271 ? 120.805 100.139 114.471 1.00 87.78  ? 271 ARG C CZ  1 
ATOM   7617  N NH1 . ARG C 1 271 ? 122.008 100.640 114.241 1.00 87.78  ? 271 ARG C NH1 1 
ATOM   7618  N NH2 . ARG C 1 271 ? 120.265 99.310  113.583 1.00 87.78  ? 271 ARG C NH2 1 
ATOM   7619  N N   . ALA C 1 272 ? 119.192 105.374 120.261 1.00 87.25  ? 272 ALA C N   1 
ATOM   7620  C CA  . ALA C 1 272 ? 119.622 106.400 121.201 1.00 87.25  ? 272 ALA C CA  1 
ATOM   7621  C C   . ALA C 1 272 ? 118.564 106.726 122.246 1.00 87.25  ? 272 ALA C C   1 
ATOM   7622  O O   . ALA C 1 272 ? 118.884 107.364 123.255 1.00 87.25  ? 272 ALA C O   1 
ATOM   7623  C CB  . ALA C 1 272 ? 120.009 107.675 120.450 1.00 87.25  ? 272 ALA C CB  1 
ATOM   7624  N N   . SER C 1 273 ? 117.316 106.309 122.031 1.00 85.83  ? 273 SER C N   1 
ATOM   7625  C CA  . SER C 1 273 ? 116.270 106.553 123.018 1.00 85.83  ? 273 SER C CA  1 
ATOM   7626  C C   . SER C 1 273 ? 116.417 105.698 124.271 1.00 85.83  ? 273 SER C C   1 
ATOM   7627  O O   . SER C 1 273 ? 115.695 105.932 125.245 1.00 85.83  ? 273 SER C O   1 
ATOM   7628  C CB  . SER C 1 273 ? 114.895 106.305 122.395 1.00 85.83  ? 273 SER C CB  1 
ATOM   7629  O OG  . SER C 1 273 ? 114.675 107.155 121.284 1.00 85.83  ? 273 SER C OG  1 
ATOM   7630  N N   . LEU C 1 274 ? 117.320 104.726 124.272 1.00 78.26  ? 274 LEU C N   1 
ATOM   7631  C CA  . LEU C 1 274 ? 117.408 103.717 125.315 1.00 78.26  ? 274 LEU C CA  1 
ATOM   7632  C C   . LEU C 1 274 ? 118.723 103.817 126.079 1.00 78.26  ? 274 LEU C C   1 
ATOM   7633  O O   . LEU C 1 274 ? 119.707 104.373 125.578 1.00 78.26  ? 274 LEU C O   1 
ATOM   7634  C CB  . LEU C 1 274 ? 117.287 102.311 124.710 1.00 78.26  ? 274 LEU C CB  1 
ATOM   7635  C CG  . LEU C 1 274 ? 115.907 101.733 124.394 1.00 78.26  ? 274 LEU C CG  1 
ATOM   7636  C CD1 . LEU C 1 274 ? 115.125 102.624 123.447 1.00 78.26  ? 274 LEU C CD1 1 
ATOM   7637  C CD2 . LEU C 1 274 ? 116.065 100.347 123.808 1.00 78.26  ? 274 LEU C CD2 1 
ATOM   7638  N N   . PRO C 1 275 ? 118.775 103.296 127.299 1.00 72.79  ? 275 PRO C N   1 
ATOM   7639  C CA  . PRO C 1 275 ? 120.050 103.161 128.009 1.00 72.79  ? 275 PRO C CA  1 
ATOM   7640  C C   . PRO C 1 275 ? 120.841 101.977 127.460 1.00 72.79  ? 275 PRO C C   1 
ATOM   7641  O O   . PRO C 1 275 ? 120.455 101.334 126.486 1.00 72.79  ? 275 PRO C O   1 
ATOM   7642  C CB  . PRO C 1 275 ? 119.622 102.930 129.458 1.00 72.79  ? 275 PRO C CB  1 
ATOM   7643  C CG  . PRO C 1 275 ? 118.286 102.299 129.352 1.00 72.79  ? 275 PRO C CG  1 
ATOM   7644  C CD  . PRO C 1 275 ? 117.632 102.896 128.138 1.00 72.79  ? 275 PRO C CD  1 
ATOM   7645  N N   . LYS C 1 276 ? 121.966 101.694 128.111 1.00 64.44  ? 276 LYS C N   1 
ATOM   7646  C CA  . LYS C 1 276 ? 122.869 100.647 127.651 1.00 64.44  ? 276 LYS C CA  1 
ATOM   7647  C C   . LYS C 1 276 ? 122.464 99.292  128.221 1.00 64.44  ? 276 LYS C C   1 
ATOM   7648  O O   . LYS C 1 276 ? 122.285 99.142  129.433 1.00 64.44  ? 276 LYS C O   1 
ATOM   7649  C CB  . LYS C 1 276 ? 124.307 100.990 128.048 1.00 64.44  ? 276 LYS C CB  1 
ATOM   7650  C CG  . LYS C 1 276 ? 125.224 99.808  128.388 1.00 64.44  ? 276 LYS C CG  1 
ATOM   7651  C CD  . LYS C 1 276 ? 125.434 98.839  127.227 1.00 64.44  ? 276 LYS C CD  1 
ATOM   7652  C CE  . LYS C 1 276 ? 126.391 97.720  127.608 1.00 64.44  ? 276 LYS C CE  1 
ATOM   7653  N NZ  . LYS C 1 276 ? 125.811 96.808  128.628 1.00 64.44  ? 276 LYS C NZ  1 
ATOM   7654  N N   . VAL C 1 277 ? 122.320 98.307  127.336 1.00 68.10  ? 277 VAL C N   1 
ATOM   7655  C CA  . VAL C 1 277 ? 122.278 96.900  127.710 1.00 68.10  ? 277 VAL C CA  1 
ATOM   7656  C C   . VAL C 1 277 ? 123.194 96.133  126.767 1.00 68.10  ? 277 VAL C C   1 
ATOM   7657  O O   . VAL C 1 277 ? 123.299 96.448  125.578 1.00 68.10  ? 277 VAL C O   1 
ATOM   7658  C CB  . VAL C 1 277 ? 120.849 96.320  127.679 1.00 68.10  ? 277 VAL C CB  1 
ATOM   7659  C CG1 . VAL C 1 277 ? 120.064 96.780  128.894 1.00 68.10  ? 277 VAL C CG1 1 
ATOM   7660  C CG2 . VAL C 1 277 ? 120.146 96.728  126.407 1.00 68.10  ? 277 VAL C CG2 1 
ATOM   7661  N N   . SER C 1 278 ? 123.863 95.114  127.309 1.00 69.27  ? 278 SER C N   1 
ATOM   7662  C CA  . SER C 1 278 ? 124.866 94.395  126.531 1.00 69.27  ? 278 SER C CA  1 
ATOM   7663  C C   . SER C 1 278 ? 124.229 93.447  125.522 1.00 69.27  ? 278 SER C C   1 
ATOM   7664  O O   . SER C 1 278 ? 124.716 93.325  124.393 1.00 69.27  ? 278 SER C O   1 
ATOM   7665  C CB  . SER C 1 278 ? 125.800 93.627  127.465 1.00 69.27  ? 278 SER C CB  1 
ATOM   7666  O OG  . SER C 1 278 ? 126.228 94.445  128.539 1.00 69.27  ? 278 SER C OG  1 
ATOM   7667  N N   . TYR C 1 279 ? 123.147 92.777  125.904 1.00 75.34  ? 279 TYR C N   1 
ATOM   7668  C CA  . TYR C 1 279 ? 122.528 91.799  125.026 1.00 75.34  ? 279 TYR C CA  1 
ATOM   7669  C C   . TYR C 1 279 ? 121.786 92.501  123.890 1.00 75.34  ? 279 TYR C C   1 
ATOM   7670  O O   . TYR C 1 279 ? 121.684 93.730  123.836 1.00 75.34  ? 279 TYR C O   1 
ATOM   7671  C CB  . TYR C 1 279 ? 121.593 90.891  125.820 1.00 75.34  ? 279 TYR C CB  1 
ATOM   7672  C CG  . TYR C 1 279 ? 121.005 91.547  127.047 1.00 75.34  ? 279 TYR C CG  1 
ATOM   7673  C CD1 . TYR C 1 279 ? 120.071 92.566  126.931 1.00 75.34  ? 279 TYR C CD1 1 
ATOM   7674  C CD2 . TYR C 1 279 ? 121.392 91.153  128.320 1.00 75.34  ? 279 TYR C CD2 1 
ATOM   7675  C CE1 . TYR C 1 279 ? 119.531 93.167  128.048 1.00 75.34  ? 279 TYR C CE1 1 
ATOM   7676  C CE2 . TYR C 1 279 ? 120.859 91.751  129.443 1.00 75.34  ? 279 TYR C CE2 1 
ATOM   7677  C CZ  . TYR C 1 279 ? 119.931 92.758  129.300 1.00 75.34  ? 279 TYR C CZ  1 
ATOM   7678  O OH  . TYR C 1 279 ? 119.395 93.359  130.415 1.00 75.34  ? 279 TYR C OH  1 
ATOM   7679  N N   . VAL C 1 280 ? 121.259 91.701  122.970 1.00 80.84  ? 280 VAL C N   1 
ATOM   7680  C CA  . VAL C 1 280 ? 120.578 92.200  121.783 1.00 80.84  ? 280 VAL C CA  1 
ATOM   7681  C C   . VAL C 1 280 ? 119.077 92.171  122.038 1.00 80.84  ? 280 VAL C C   1 
ATOM   7682  O O   . VAL C 1 280 ? 118.543 91.180  122.553 1.00 80.84  ? 280 VAL C O   1 
ATOM   7683  C CB  . VAL C 1 280 ? 120.961 91.378  120.539 1.00 80.84  ? 280 VAL C CB  1 
ATOM   7684  C CG1 . VAL C 1 280 ? 120.700 89.889  120.760 1.00 80.84  ? 280 VAL C CG1 1 
ATOM   7685  C CG2 . VAL C 1 280 ? 120.229 91.891  119.315 1.00 80.84  ? 280 VAL C CG2 1 
ATOM   7686  N N   . LYS C 1 281 ? 118.400 93.262  121.697 1.00 71.19  ? 281 LYS C N   1 
ATOM   7687  C CA  . LYS C 1 281 ? 116.998 93.473  122.027 1.00 71.19  ? 281 LYS C CA  1 
ATOM   7688  C C   . LYS C 1 281 ? 116.119 93.287  120.793 1.00 71.19  ? 281 LYS C C   1 
ATOM   7689  O O   . LYS C 1 281 ? 116.586 92.930  119.708 1.00 71.19  ? 281 LYS C O   1 
ATOM   7690  C CB  . LYS C 1 281 ? 116.802 94.864  122.626 1.00 71.19  ? 281 LYS C CB  1 
ATOM   7691  C CG  . LYS C 1 281 ? 117.291 95.972  121.721 1.00 71.19  ? 281 LYS C CG  1 
ATOM   7692  C CD  . LYS C 1 281 ? 117.256 97.311  122.419 1.00 71.19  ? 281 LYS C CD  1 
ATOM   7693  C CE  . LYS C 1 281 ? 118.317 97.395  123.489 1.00 71.19  ? 281 LYS C CE  1 
ATOM   7694  N NZ  . LYS C 1 281 ? 119.679 97.253  122.915 1.00 71.19  ? 281 LYS C NZ  1 
ATOM   7695  N N   . ALA C 1 282 ? 114.819 93.524  120.980 1.00 68.29  ? 282 ALA C N   1 
ATOM   7696  C CA  . ALA C 1 282 ? 113.867 93.389  119.882 1.00 68.29  ? 282 ALA C CA  1 
ATOM   7697  C C   . ALA C 1 282 ? 114.062 94.478  118.838 1.00 68.29  ? 282 ALA C C   1 
ATOM   7698  O O   . ALA C 1 282 ? 114.154 94.196  117.636 1.00 68.29  ? 282 ALA C O   1 
ATOM   7699  C CB  . ALA C 1 282 ? 112.439 93.434  120.423 1.00 68.29  ? 282 ALA C CB  1 
ATOM   7700  N N   . ILE C 1 283 ? 114.120 95.734  119.280 1.00 64.53  ? 283 ILE C N   1 
ATOM   7701  C CA  . ILE C 1 283 ? 114.138 96.839  118.332 1.00 64.53  ? 283 ILE C CA  1 
ATOM   7702  C C   . ILE C 1 283 ? 115.463 96.873  117.582 1.00 64.53  ? 283 ILE C C   1 
ATOM   7703  O O   . ILE C 1 283 ? 115.509 97.212  116.394 1.00 64.53  ? 283 ILE C O   1 
ATOM   7704  C CB  . ILE C 1 283 ? 113.832 98.164  119.052 1.00 64.53  ? 283 ILE C CB  1 
ATOM   7705  C CG1 . ILE C 1 283 ? 113.585 99.276  118.041 1.00 64.53  ? 283 ILE C CG1 1 
ATOM   7706  C CG2 . ILE C 1 283 ? 114.951 98.555  119.994 1.00 64.53  ? 283 ILE C CG2 1 
ATOM   7707  C CD1 . ILE C 1 283 ? 112.762 100.394 118.606 1.00 64.53  ? 283 ILE C CD1 1 
ATOM   7708  N N   . ASP C 1 284 ? 116.557 96.505  118.253 1.00 72.36  ? 284 ASP C N   1 
ATOM   7709  C CA  . ASP C 1 284 ? 117.840 96.408  117.568 1.00 72.36  ? 284 ASP C CA  1 
ATOM   7710  C C   . ASP C 1 284 ? 117.806 95.338  116.486 1.00 72.36  ? 284 ASP C C   1 
ATOM   7711  O O   . ASP C 1 284 ? 118.318 95.548  115.382 1.00 72.36  ? 284 ASP C O   1 
ATOM   7712  C CB  . ASP C 1 284 ? 118.955 96.116  118.569 1.00 72.36  ? 284 ASP C CB  1 
ATOM   7713  C CG  . ASP C 1 284 ? 120.268 96.747  118.171 1.00 72.36  ? 284 ASP C CG  1 
ATOM   7714  O OD1 . ASP C 1 284 ? 120.240 97.817  117.530 1.00 72.36  ? 284 ASP C OD1 1 
ATOM   7715  O OD2 . ASP C 1 284 ? 121.327 96.170  118.492 1.00 72.36  ? 284 ASP C OD2 1 
ATOM   7716  N N   . ILE C 1 285 ? 117.210 94.182  116.784 1.00 69.68  ? 285 ILE C N   1 
ATOM   7717  C CA  . ILE C 1 285 ? 117.099 93.124  115.784 1.00 69.68  ? 285 ILE C CA  1 
ATOM   7718  C C   . ILE C 1 285 ? 116.281 93.609  114.593 1.00 69.68  ? 285 ILE C C   1 
ATOM   7719  O O   . ILE C 1 285 ? 116.658 93.404  113.432 1.00 69.68  ? 285 ILE C O   1 
ATOM   7720  C CB  . ILE C 1 285 ? 116.493 91.854  116.408 1.00 69.68  ? 285 ILE C CB  1 
ATOM   7721  C CG1 . ILE C 1 285 ? 117.570 91.040  117.123 1.00 69.68  ? 285 ILE C CG1 1 
ATOM   7722  C CG2 . ILE C 1 285 ? 115.802 91.007  115.351 1.00 69.68  ? 285 ILE C CG2 1 
ATOM   7723  C CD1 . ILE C 1 285 ? 117.106 89.667  117.561 1.00 69.68  ? 285 ILE C CD1 1 
ATOM   7724  N N   . TRP C 1 286 ? 115.151 94.266  114.866 1.00 71.24  ? 286 TRP C N   1 
ATOM   7725  C CA  . TRP C 1 286 ? 114.304 94.749  113.780 1.00 71.24  ? 286 TRP C CA  1 
ATOM   7726  C C   . TRP C 1 286 ? 115.043 95.759  112.914 1.00 71.24  ? 286 TRP C C   1 
ATOM   7727  O O   . TRP C 1 286 ? 115.006 95.677  111.679 1.00 71.24  ? 286 TRP C O   1 
ATOM   7728  C CB  . TRP C 1 286 ? 113.026 95.363  114.348 1.00 71.24  ? 286 TRP C CB  1 
ATOM   7729  C CG  . TRP C 1 286 ? 112.143 96.017  113.324 1.00 71.24  ? 286 TRP C CG  1 
ATOM   7730  C CD1 . TRP C 1 286 ? 112.208 97.306  112.888 1.00 71.24  ? 286 TRP C CD1 1 
ATOM   7731  C CD2 . TRP C 1 286 ? 111.044 95.415  112.631 1.00 71.24  ? 286 TRP C CD2 1 
ATOM   7732  N NE1 . TRP C 1 286 ? 111.227 97.543  111.958 1.00 71.24  ? 286 TRP C NE1 1 
ATOM   7733  C CE2 . TRP C 1 286 ? 110.498 96.397  111.783 1.00 71.24  ? 286 TRP C CE2 1 
ATOM   7734  C CE3 . TRP C 1 286 ? 110.474 94.140  112.641 1.00 71.24  ? 286 TRP C CE3 1 
ATOM   7735  C CZ2 . TRP C 1 286 ? 109.410 96.143  110.954 1.00 71.24  ? 286 TRP C CZ2 1 
ATOM   7736  C CZ3 . TRP C 1 286 ? 109.395 93.891  111.818 1.00 71.24  ? 286 TRP C CZ3 1 
ATOM   7737  C CH2 . TRP C 1 286 ? 108.874 94.886  110.986 1.00 71.24  ? 286 TRP C CH2 1 
ATOM   7738  N N   . MET C 1 287 ? 115.737 96.710  113.544 1.00 76.37  ? 287 MET C N   1 
ATOM   7739  C CA  . MET C 1 287 ? 116.467 97.716  112.781 1.00 76.37  ? 287 MET C CA  1 
ATOM   7740  C C   . MET C 1 287 ? 117.606 97.091  111.985 1.00 76.37  ? 287 MET C C   1 
ATOM   7741  O O   . MET C 1 287 ? 117.859 97.488  110.844 1.00 76.37  ? 287 MET C O   1 
ATOM   7742  C CB  . MET C 1 287 ? 117.000 98.804  113.712 1.00 76.37  ? 287 MET C CB  1 
ATOM   7743  C CG  . MET C 1 287 ? 115.928 99.704  114.296 1.00 76.37  ? 287 MET C CG  1 
ATOM   7744  S SD  . MET C 1 287 ? 114.406 99.718  113.332 1.00 76.37  ? 287 MET C SD  1 
ATOM   7745  C CE  . MET C 1 287 ? 114.799 100.905 112.051 1.00 76.37  ? 287 MET C CE  1 
ATOM   7746  N N   . ALA C 1 288 ? 118.307 96.115  112.568 1.00 73.51  ? 288 ALA C N   1 
ATOM   7747  C CA  . ALA C 1 288 ? 119.402 95.465  111.857 1.00 73.51  ? 288 ALA C CA  1 
ATOM   7748  C C   . ALA C 1 288 ? 118.897 94.696  110.645 1.00 73.51  ? 288 ALA C C   1 
ATOM   7749  O O   . ALA C 1 288 ? 119.525 94.722  109.580 1.00 73.51  ? 288 ALA C O   1 
ATOM   7750  C CB  . ALA C 1 288 ? 120.167 94.539  112.801 1.00 73.51  ? 288 ALA C CB  1 
ATOM   7751  N N   . VAL C 1 289 ? 117.767 94.002  110.782 1.00 75.63  ? 289 VAL C N   1 
ATOM   7752  C CA  . VAL C 1 289 ? 117.234 93.265  109.642 1.00 75.63  ? 289 VAL C CA  1 
ATOM   7753  C C   . VAL C 1 289 ? 116.733 94.227  108.572 1.00 75.63  ? 289 VAL C C   1 
ATOM   7754  O O   . VAL C 1 289 ? 116.889 93.974  107.371 1.00 75.63  ? 289 VAL C O   1 
ATOM   7755  C CB  . VAL C 1 289 ? 116.138 92.287  110.093 1.00 75.63  ? 289 VAL C CB  1 
ATOM   7756  C CG1 . VAL C 1 289 ? 115.514 91.608  108.887 1.00 75.63  ? 289 VAL C CG1 1 
ATOM   7757  C CG2 . VAL C 1 289 ? 116.724 91.253  111.035 1.00 75.63  ? 289 VAL C CG2 1 
ATOM   7758  N N   . CYS C 1 290 ? 116.135 95.348  108.982 1.00 77.25  ? 290 CYS C N   1 
ATOM   7759  C CA  . CYS C 1 290 ? 115.755 96.366  108.008 1.00 77.25  ? 290 CYS C CA  1 
ATOM   7760  C C   . CYS C 1 290 ? 116.979 96.908  107.281 1.00 77.25  ? 290 CYS C C   1 
ATOM   7761  O O   . CYS C 1 290 ? 116.945 97.130  106.064 1.00 77.25  ? 290 CYS C O   1 
ATOM   7762  C CB  . CYS C 1 290 ? 114.999 97.498  108.699 1.00 77.25  ? 290 CYS C CB  1 
ATOM   7763  S SG  . CYS C 1 290 ? 114.339 98.746  107.574 1.00 77.25  ? 290 CYS C SG  1 
ATOM   7764  N N   . LEU C 1 291 ? 118.071 97.124  108.016 1.00 81.66  ? 291 LEU C N   1 
ATOM   7765  C CA  . LEU C 1 291 ? 119.318 97.570  107.407 1.00 81.66  ? 291 LEU C CA  1 
ATOM   7766  C C   . LEU C 1 291 ? 119.807 96.558  106.382 1.00 81.66  ? 291 LEU C C   1 
ATOM   7767  O O   . LEU C 1 291 ? 120.185 96.918  105.261 1.00 81.66  ? 291 LEU C O   1 
ATOM   7768  C CB  . LEU C 1 291 ? 120.362 97.811  108.506 1.00 81.66  ? 291 LEU C CB  1 
ATOM   7769  C CG  . LEU C 1 291 ? 121.808 98.294  108.303 1.00 81.66  ? 291 LEU C CG  1 
ATOM   7770  C CD1 . LEU C 1 291 ? 122.447 98.529  109.660 1.00 81.66  ? 291 LEU C CD1 1 
ATOM   7771  C CD2 . LEU C 1 291 ? 122.682 97.319  107.527 1.00 81.66  ? 291 LEU C CD2 1 
ATOM   7772  N N   . LEU C 1 292 ? 119.795 95.278  106.752 1.00 81.61  ? 292 LEU C N   1 
ATOM   7773  C CA  . LEU C 1 292 ? 120.244 94.235  105.836 1.00 81.61  ? 292 LEU C CA  1 
ATOM   7774  C C   . LEU C 1 292 ? 119.381 94.196  104.582 1.00 81.61  ? 292 LEU C C   1 
ATOM   7775  O O   . LEU C 1 292 ? 119.896 94.053  103.470 1.00 81.61  ? 292 LEU C O   1 
ATOM   7776  C CB  . LEU C 1 292 ? 120.236 92.885  106.552 1.00 81.61  ? 292 LEU C CB  1 
ATOM   7777  C CG  . LEU C 1 292 ? 120.737 91.658  105.788 1.00 81.61  ? 292 LEU C CG  1 
ATOM   7778  C CD1 . LEU C 1 292 ? 121.765 90.920  106.624 1.00 81.61  ? 292 LEU C CD1 1 
ATOM   7779  C CD2 . LEU C 1 292 ? 119.577 90.738  105.442 1.00 81.61  ? 292 LEU C CD2 1 
ATOM   7780  N N   . PHE C 1 293 ? 118.065 94.352  104.738 1.00 79.27  ? 293 PHE C N   1 
ATOM   7781  C CA  . PHE C 1 293 ? 117.173 94.271  103.585 1.00 79.27  ? 293 PHE C CA  1 
ATOM   7782  C C   . PHE C 1 293 ? 117.343 95.467  102.654 1.00 79.27  ? 293 PHE C C   1 
ATOM   7783  O O   . PHE C 1 293 ? 117.358 95.306  101.428 1.00 79.27  ? 293 PHE C O   1 
ATOM   7784  C CB  . PHE C 1 293 ? 115.724 94.150  104.050 1.00 79.27  ? 293 PHE C CB  1 
ATOM   7785  C CG  . PHE C 1 293 ? 115.320 92.749  104.409 1.00 79.27  ? 293 PHE C CG  1 
ATOM   7786  C CD1 . PHE C 1 293 ? 116.275 91.794  104.714 1.00 79.27  ? 293 PHE C CD1 1 
ATOM   7787  C CD2 . PHE C 1 293 ? 113.987 92.387  104.441 1.00 79.27  ? 293 PHE C CD2 1 
ATOM   7788  C CE1 . PHE C 1 293 ? 115.907 90.506  105.043 1.00 79.27  ? 293 PHE C CE1 1 
ATOM   7789  C CE2 . PHE C 1 293 ? 113.614 91.101  104.770 1.00 79.27  ? 293 PHE C CE2 1 
ATOM   7790  C CZ  . PHE C 1 293 ? 114.574 90.159  105.071 1.00 79.27  ? 293 PHE C CZ  1 
ATOM   7791  N N   . VAL C 1 294 ? 117.476 96.673  103.207 1.00 87.78  ? 294 VAL C N   1 
ATOM   7792  C CA  . VAL C 1 294 ? 117.674 97.837  102.345 1.00 87.78  ? 294 VAL C CA  1 
ATOM   7793  C C   . VAL C 1 294 ? 119.045 97.782  101.676 1.00 87.78  ? 294 VAL C C   1 
ATOM   7794  O O   . VAL C 1 294 ? 119.205 98.183  100.514 1.00 87.78  ? 294 VAL C O   1 
ATOM   7795  C CB  . VAL C 1 294 ? 117.470 99.138  103.141 1.00 87.78  ? 294 VAL C CB  1 
ATOM   7796  C CG1 . VAL C 1 294 ? 117.603 100.337 102.225 1.00 87.78  ? 294 VAL C CG1 1 
ATOM   7797  C CG2 . VAL C 1 294 ? 116.103 99.140  103.801 1.00 87.78  ? 294 VAL C CG2 1 
ATOM   7798  N N   . PHE C 1 295 ? 120.054 97.277  102.390 1.00 94.16  ? 295 PHE C N   1 
ATOM   7799  C CA  . PHE C 1 295 ? 121.366 97.087  101.782 1.00 94.16  ? 295 PHE C CA  1 
ATOM   7800  C C   . PHE C 1 295 ? 121.306 96.055  100.662 1.00 94.16  ? 295 PHE C C   1 
ATOM   7801  O O   . PHE C 1 295 ? 121.984 96.196  99.638  1.00 94.16  ? 295 PHE C O   1 
ATOM   7802  C CB  . PHE C 1 295 ? 122.375 96.677  102.854 1.00 94.16  ? 295 PHE C CB  1 
ATOM   7803  C CG  . PHE C 1 295 ? 123.788 96.607  102.364 1.00 94.16  ? 295 PHE C CG  1 
ATOM   7804  C CD1 . PHE C 1 295 ? 124.441 97.749  101.936 1.00 94.16  ? 295 PHE C CD1 1 
ATOM   7805  C CD2 . PHE C 1 295 ? 124.470 95.404  102.349 1.00 94.16  ? 295 PHE C CD2 1 
ATOM   7806  C CE1 . PHE C 1 295 ? 125.744 97.689  101.487 1.00 94.16  ? 295 PHE C CE1 1 
ATOM   7807  C CE2 . PHE C 1 295 ? 125.775 95.338  101.903 1.00 94.16  ? 295 PHE C CE2 1 
ATOM   7808  C CZ  . PHE C 1 295 ? 126.413 96.482  101.472 1.00 94.16  ? 295 PHE C CZ  1 
ATOM   7809  N N   . SER C 1 296 ? 120.497 95.008  100.839 1.00 91.68  ? 296 SER C N   1 
ATOM   7810  C CA  . SER C 1 296 ? 120.298 94.033  99.772  1.00 91.68  ? 296 SER C CA  1 
ATOM   7811  C C   . SER C 1 296 ? 119.585 94.660  98.583  1.00 91.68  ? 296 SER C C   1 
ATOM   7812  O O   . SER C 1 296 ? 119.852 94.300  97.434  1.00 91.68  ? 296 SER C O   1 
ATOM   7813  C CB  . SER C 1 296 ? 119.514 92.831  100.297 1.00 91.68  ? 296 SER C CB  1 
ATOM   7814  O OG  . SER C 1 296 ? 120.386 91.791  100.706 1.00 91.68  ? 296 SER C OG  1 
ATOM   7815  N N   . ALA C 1 297 ? 118.665 95.591  98.841  1.00 93.62  ? 297 ALA C N   1 
ATOM   7816  C CA  . ALA C 1 297 ? 118.039 96.327  97.746  1.00 93.62  ? 297 ALA C CA  1 
ATOM   7817  C C   . ALA C 1 297 ? 119.069 97.149  96.976  1.00 93.62  ? 297 ALA C C   1 
ATOM   7818  O O   . ALA C 1 297 ? 119.051 97.186  95.738  1.00 93.62  ? 297 ALA C O   1 
ATOM   7819  C CB  . ALA C 1 297 ? 116.928 97.227  98.285  1.00 93.62  ? 297 ALA C CB  1 
ATOM   7820  N N   . LEU C 1 298 ? 119.976 97.813  97.695  1.00 97.57  ? 298 LEU C N   1 
ATOM   7821  C CA  . LEU C 1 298 ? 121.044 98.557  97.029  1.00 97.57  ? 298 LEU C CA  1 
ATOM   7822  C C   . LEU C 1 298 ? 121.943 97.624  96.223  1.00 97.57  ? 298 LEU C C   1 
ATOM   7823  O O   . LEU C 1 298 ? 122.358 97.956  95.104  1.00 97.57  ? 298 LEU C O   1 
ATOM   7824  C CB  . LEU C 1 298 ? 121.866 99.340  98.054  1.00 97.57  ? 298 LEU C CB  1 
ATOM   7825  C CG  . LEU C 1 298 ? 123.236 99.859  97.598  1.00 97.57  ? 298 LEU C CG  1 
ATOM   7826  C CD1 . LEU C 1 298 ? 123.099 100.856 96.455  1.00 97.57  ? 298 LEU C CD1 1 
ATOM   7827  C CD2 . LEU C 1 298 ? 124.000 100.480 98.760  1.00 97.57  ? 298 LEU C CD2 1 
ATOM   7828  N N   . LEU C 1 299 ? 122.259 96.454  96.780  1.00 95.14  ? 299 LEU C N   1 
ATOM   7829  C CA  . LEU C 1 299 ? 123.066 95.479  96.054  1.00 95.14  ? 299 LEU C CA  1 
ATOM   7830  C C   . LEU C 1 299 ? 122.344 94.970  94.814  1.00 95.14  ? 299 LEU C C   1 
ATOM   7831  O O   . LEU C 1 299 ? 122.981 94.712  93.790  1.00 95.14  ? 299 LEU C O   1 
ATOM   7832  C CB  . LEU C 1 299 ? 123.437 94.315  96.971  1.00 95.14  ? 299 LEU C CB  1 
ATOM   7833  C CG  . LEU C 1 299 ? 124.452 94.629  98.071  1.00 95.14  ? 299 LEU C CG  1 
ATOM   7834  C CD1 . LEU C 1 299 ? 124.981 93.345  98.693  1.00 95.14  ? 299 LEU C CD1 1 
ATOM   7835  C CD2 . LEU C 1 299 ? 125.592 95.480  97.529  1.00 95.14  ? 299 LEU C CD2 1 
ATOM   7836  N N   . GLU C 1 300 ? 121.022 94.811  94.890  1.00 96.18  ? 300 GLU C N   1 
ATOM   7837  C CA  . GLU C 1 300 ? 120.247 94.441  93.711  1.00 96.18  ? 300 GLU C CA  1 
ATOM   7838  C C   . GLU C 1 300 ? 120.306 95.535  92.654  1.00 96.18  ? 300 GLU C C   1 
ATOM   7839  O O   . GLU C 1 300 ? 120.417 95.244  91.457  1.00 96.18  ? 300 GLU C O   1 
ATOM   7840  C CB  . GLU C 1 300 ? 118.798 94.152  94.101  1.00 96.18  ? 300 GLU C CB  1 
ATOM   7841  C CG  . GLU C 1 300 ? 118.012 93.376  93.054  1.00 96.18  ? 300 GLU C CG  1 
ATOM   7842  C CD  . GLU C 1 300 ? 117.286 94.279  92.076  1.00 96.18  ? 300 GLU C CD  1 
ATOM   7843  O OE1 . GLU C 1 300 ? 117.265 95.507  92.300  1.00 96.18  ? 300 GLU C OE1 1 
ATOM   7844  O OE2 . GLU C 1 300 ? 116.734 93.759  91.083  1.00 96.18  ? 300 GLU C OE2 1 
ATOM   7845  N N   . TYR C 1 301 ? 120.224 96.798  93.078  1.00 97.21  ? 301 TYR C N   1 
ATOM   7846  C CA  . TYR C 1 301 ? 120.383 97.898  92.130  1.00 97.21  ? 301 TYR C CA  1 
ATOM   7847  C C   . TYR C 1 301 ? 121.743 97.834  91.446  1.00 97.21  ? 301 TYR C C   1 
ATOM   7848  O O   . TYR C 1 301 ? 121.843 97.979  90.220  1.00 97.21  ? 301 TYR C O   1 
ATOM   7849  C CB  . TYR C 1 301 ? 120.216 99.245  92.837  1.00 97.21  ? 301 TYR C CB  1 
ATOM   7850  C CG  . TYR C 1 301 ? 118.929 99.410  93.614  1.00 97.21  ? 301 TYR C CG  1 
ATOM   7851  C CD1 . TYR C 1 301 ? 117.757 98.790  93.203  1.00 97.21  ? 301 TYR C CD1 1 
ATOM   7852  C CD2 . TYR C 1 301 ? 118.885 100.203 94.754  1.00 97.21  ? 301 TYR C CD2 1 
ATOM   7853  C CE1 . TYR C 1 301 ? 116.580 98.946  93.912  1.00 97.21  ? 301 TYR C CE1 1 
ATOM   7854  C CE2 . TYR C 1 301 ? 117.716 100.364 95.469  1.00 97.21  ? 301 TYR C CE2 1 
ATOM   7855  C CZ  . TYR C 1 301 ? 116.566 99.734  95.044  1.00 97.21  ? 301 TYR C CZ  1 
ATOM   7856  O OH  . TYR C 1 301 ? 115.397 99.893  95.753  1.00 97.21  ? 301 TYR C OH  1 
ATOM   7857  N N   . ALA C 1 302 ? 122.799 97.605  92.229  1.00 95.84  ? 302 ALA C N   1 
ATOM   7858  C CA  . ALA C 1 302 ? 124.142 97.517  91.663  1.00 95.84  ? 302 ALA C CA  1 
ATOM   7859  C C   . ALA C 1 302 ? 124.266 96.338  90.705  1.00 95.84  ? 302 ALA C C   1 
ATOM   7860  O O   . ALA C 1 302 ? 124.897 96.452  89.649  1.00 95.84  ? 302 ALA C O   1 
ATOM   7861  C CB  . ALA C 1 302 ? 125.178 97.409  92.782  1.00 95.84  ? 302 ALA C CB  1 
ATOM   7862  N N   . ALA C 1 303 ? 123.678 95.195  91.062  1.00 92.56  ? 303 ALA C N   1 
ATOM   7863  C CA  . ALA C 1 303 ? 123.745 94.019  90.199  1.00 92.56  ? 303 ALA C CA  1 
ATOM   7864  C C   . ALA C 1 303 ? 123.005 94.247  88.888  1.00 92.56  ? 303 ALA C C   1 
ATOM   7865  O O   . ALA C 1 303 ? 123.476 93.828  87.824  1.00 92.56  ? 303 ALA C O   1 
ATOM   7866  C CB  . ALA C 1 303 ? 123.181 92.800  90.928  1.00 92.56  ? 303 ALA C CB  1 
ATOM   7867  N N   . VAL C 1 304 ? 121.838 94.894  88.945  1.00 93.71  ? 304 VAL C N   1 
ATOM   7868  C CA  . VAL C 1 304 ? 121.102 95.198  87.722  1.00 93.71  ? 304 VAL C CA  1 
ATOM   7869  C C   . VAL C 1 304 ? 121.894 96.166  86.853  1.00 93.71  ? 304 VAL C C   1 
ATOM   7870  O O   . VAL C 1 304 ? 121.955 96.011  85.627  1.00 93.71  ? 304 VAL C O   1 
ATOM   7871  C CB  . VAL C 1 304 ? 119.703 95.745  88.056  1.00 93.71  ? 304 VAL C CB  1 
ATOM   7872  C CG1 . VAL C 1 304 ? 119.017 96.256  86.798  1.00 93.71  ? 304 VAL C CG1 1 
ATOM   7873  C CG2 . VAL C 1 304 ? 118.859 94.666  88.712  1.00 93.71  ? 304 VAL C CG2 1 
ATOM   7874  N N   . ASN C 1 305 ? 122.520 97.172  87.469  1.00 92.01  ? 305 ASN C N   1 
ATOM   7875  C CA  . ASN C 1 305 ? 123.366 98.085  86.707  1.00 92.01  ? 305 ASN C CA  1 
ATOM   7876  C C   . ASN C 1 305 ? 124.531 97.345  86.057  1.00 92.01  ? 305 ASN C C   1 
ATOM   7877  O O   . ASN C 1 305 ? 124.891 97.625  84.907  1.00 92.01  ? 305 ASN C O   1 
ATOM   7878  C CB  . ASN C 1 305 ? 123.880 99.203  87.613  1.00 92.01  ? 305 ASN C CB  1 
ATOM   7879  C CG  . ASN C 1 305 ? 124.802 100.162 86.888  1.00 92.01  ? 305 ASN C CG  1 
ATOM   7880  O OD1 . ASN C 1 305 ? 124.615 100.447 85.706  1.00 92.01  ? 305 ASN C OD1 1 
ATOM   7881  N ND2 . ASN C 1 305 ? 125.809 100.663 87.595  1.00 92.01  ? 305 ASN C ND2 1 
ATOM   7882  N N   . PHE C 1 306 ? 125.133 96.400  86.782  1.00 87.32  ? 306 PHE C N   1 
ATOM   7883  C CA  . PHE C 1 306 ? 126.269 95.654  86.249  1.00 87.32  ? 306 PHE C CA  1 
ATOM   7884  C C   . PHE C 1 306 ? 125.854 94.777  85.073  1.00 87.32  ? 306 PHE C C   1 
ATOM   7885  O O   . PHE C 1 306 ? 126.504 94.785  84.021  1.00 87.32  ? 306 PHE C O   1 
ATOM   7886  C CB  . PHE C 1 306 ? 126.898 94.806  87.355  1.00 87.32  ? 306 PHE C CB  1 
ATOM   7887  C CG  . PHE C 1 306 ? 128.341 94.463  87.113  1.00 87.32  ? 306 PHE C CG  1 
ATOM   7888  C CD1 . PHE C 1 306 ? 129.320 95.442  87.170  1.00 87.32  ? 306 PHE C CD1 1 
ATOM   7889  C CD2 . PHE C 1 306 ? 128.718 93.160  86.835  1.00 87.32  ? 306 PHE C CD2 1 
ATOM   7890  C CE1 . PHE C 1 306 ? 130.647 95.127  86.950  1.00 87.32  ? 306 PHE C CE1 1 
ATOM   7891  C CE2 . PHE C 1 306 ? 130.044 92.839  86.615  1.00 87.32  ? 306 PHE C CE2 1 
ATOM   7892  C CZ  . PHE C 1 306 ? 131.009 93.824  86.673  1.00 87.32  ? 306 PHE C CZ  1 
ATOM   7893  N N   . VAL C 1 307 ? 124.771 94.014  85.231  1.00 93.37  ? 307 VAL C N   1 
ATOM   7894  C CA  . VAL C 1 307 ? 124.351 93.106  84.168  1.00 93.37  ? 307 VAL C CA  1 
ATOM   7895  C C   . VAL C 1 307 ? 123.673 93.838  83.018  1.00 93.37  ? 307 VAL C C   1 
ATOM   7896  O O   . VAL C 1 307 ? 123.498 93.253  81.942  1.00 93.37  ? 307 VAL C O   1 
ATOM   7897  C CB  . VAL C 1 307 ? 123.415 92.009  84.703  1.00 93.37  ? 307 VAL C CB  1 
ATOM   7898  C CG1 . VAL C 1 307 ? 124.105 91.210  85.800  1.00 93.37  ? 307 VAL C CG1 1 
ATOM   7899  C CG2 . VAL C 1 307 ? 122.115 92.614  85.201  1.00 93.37  ? 307 VAL C CG2 1 
ATOM   7900  N N   . SER C 1 308 ? 123.277 95.098  83.214  1.00 96.50  ? 308 SER C N   1 
ATOM   7901  C CA  . SER C 1 308 ? 122.739 95.879  82.106  1.00 96.50  ? 308 SER C CA  1 
ATOM   7902  C C   . SER C 1 308 ? 123.798 96.106  81.034  1.00 96.50  ? 308 SER C C   1 
ATOM   7903  O O   . SER C 1 308 ? 123.502 96.050  79.835  1.00 96.50  ? 308 SER C O   1 
ATOM   7904  C CB  . SER C 1 308 ? 122.194 97.211  82.621  1.00 96.50  ? 308 SER C CB  1 
ATOM   7905  O OG  . SER C 1 308 ? 123.216 97.980  83.230  1.00 96.50  ? 308 SER C OG  1 
ATOM   7906  N N   . ARG C 1 309 ? 125.036 96.364  81.447  1.00 103.34 ? 309 ARG C N   1 
ATOM   7907  C CA  . ARG C 1 309 ? 126.131 96.496  80.502  1.00 103.34 ? 309 ARG C CA  1 
ATOM   7908  C C   . ARG C 1 309 ? 126.487 95.136  79.906  1.00 103.34 ? 309 ARG C C   1 
ATOM   7909  O O   . ARG C 1 309 ? 126.149 94.080  80.448  1.00 103.34 ? 309 ARG C O   1 
ATOM   7910  C CB  . ARG C 1 309 ? 127.354 97.113  81.181  1.00 103.34 ? 309 ARG C CB  1 
ATOM   7911  N N   . GLN C 1 310 ? 127.180 95.175  78.771  1.00 105.62 ? 310 GLN C N   1 
ATOM   7912  C CA  . GLN C 1 310 ? 127.561 93.960  78.058  1.00 105.62 ? 310 GLN C CA  1 
ATOM   7913  C C   . GLN C 1 310 ? 128.492 93.087  78.895  1.00 105.62 ? 310 GLN C C   1 
ATOM   7914  O O   . GLN C 1 310 ? 128.222 91.906  79.111  1.00 105.62 ? 310 GLN C O   1 
ATOM   7915  C CB  . GLN C 1 310 ? 128.230 94.309  76.727  1.00 105.62 ? 310 GLN C CB  1 
ATOM   7916  C CG  . GLN C 1 310 ? 129.746 94.418  76.799  1.00 105.62 ? 310 GLN C CG  1 
ATOM   7917  C CD  . GLN C 1 310 ? 130.212 95.607  77.615  1.00 105.62 ? 310 GLN C CD  1 
ATOM   7918  O OE1 . GLN C 1 310 ? 129.502 96.604  77.743  1.00 105.62 ? 310 GLN C OE1 1 
ATOM   7919  N NE2 . GLN C 1 310 ? 131.412 95.505  78.173  1.00 105.62 ? 310 GLN C NE2 1 
ATOM   7920  N N   . LYS C 1 377 ? 124.099 87.073  73.314  1.00 94.38  ? 386 LYS C N   1 
ATOM   7921  C CA  . LYS C 1 377 ? 124.434 86.779  74.702  1.00 94.38  ? 386 LYS C CA  1 
ATOM   7922  C C   . LYS C 1 377 ? 123.191 86.832  75.586  1.00 94.38  ? 386 LYS C C   1 
ATOM   7923  O O   . LYS C 1 377 ? 123.224 86.386  76.734  1.00 94.38  ? 386 LYS C O   1 
ATOM   7924  C CB  . LYS C 1 377 ? 125.492 87.757  75.216  1.00 94.38  ? 386 LYS C CB  1 
ATOM   7925  C CG  . LYS C 1 377 ? 126.282 87.250  76.412  1.00 94.38  ? 386 LYS C CG  1 
ATOM   7926  C CD  . LYS C 1 377 ? 127.339 88.253  76.846  1.00 94.38  ? 386 LYS C CD  1 
ATOM   7927  C CE  . LYS C 1 377 ? 128.160 87.719  78.009  1.00 94.38  ? 386 LYS C CE  1 
ATOM   7928  N NZ  . LYS C 1 377 ? 129.189 88.695  78.461  1.00 94.38  ? 386 LYS C NZ  1 
ATOM   7929  N N   . VAL C 1 378 ? 122.102 87.365  75.020  1.00 102.47 ? 387 VAL C N   1 
ATOM   7930  C CA  . VAL C 1 378 ? 120.802 87.563  75.667  1.00 102.47 ? 387 VAL C CA  1 
ATOM   7931  C C   . VAL C 1 378 ? 120.939 87.888  77.151  1.00 102.47 ? 387 VAL C C   1 
ATOM   7932  O O   . VAL C 1 378 ? 120.206 87.350  77.989  1.00 102.47 ? 387 VAL C O   1 
ATOM   7933  C CB  . VAL C 1 378 ? 119.868 86.350  75.453  1.00 102.47 ? 387 VAL C CB  1 
ATOM   7934  C CG1 . VAL C 1 378 ? 119.486 86.231  73.985  1.00 102.47 ? 387 VAL C CG1 1 
ATOM   7935  C CG2 . VAL C 1 378 ? 120.488 85.046  75.953  1.00 102.47 ? 387 VAL C CG2 1 
ATOM   7936  N N   . PHE C 1 379 ? 121.872 88.785  77.486  1.00 107.69 ? 388 PHE C N   1 
ATOM   7937  C CA  . PHE C 1 379 ? 122.017 89.219  78.870  1.00 107.69 ? 388 PHE C CA  1 
ATOM   7938  C C   . PHE C 1 379 ? 120.812 90.016  79.352  1.00 107.69 ? 388 PHE C C   1 
ATOM   7939  O O   . PHE C 1 379 ? 120.581 90.092  80.563  1.00 107.69 ? 388 PHE C O   1 
ATOM   7940  C CB  . PHE C 1 379 ? 123.292 90.047  79.038  1.00 107.69 ? 388 PHE C CB  1 
ATOM   7941  C CG  . PHE C 1 379 ? 123.558 90.992  77.902  1.00 107.69 ? 388 PHE C CG  1 
ATOM   7942  C CD1 . PHE C 1 379 ? 122.894 92.204  77.819  1.00 107.69 ? 388 PHE C CD1 1 
ATOM   7943  C CD2 . PHE C 1 379 ? 124.480 90.672  76.919  1.00 107.69 ? 388 PHE C CD2 1 
ATOM   7944  C CE1 . PHE C 1 379 ? 123.140 93.075  76.774  1.00 107.69 ? 388 PHE C CE1 1 
ATOM   7945  C CE2 . PHE C 1 379 ? 124.731 91.539  75.872  1.00 107.69 ? 388 PHE C CE2 1 
ATOM   7946  C CZ  . PHE C 1 379 ? 124.060 92.742  75.799  1.00 107.69 ? 388 PHE C CZ  1 
ATOM   7947  N N   . ILE C 1 380 ? 120.044 90.608  78.435  1.00 109.48 ? 389 ILE C N   1 
ATOM   7948  C CA  . ILE C 1 380 ? 118.849 91.351  78.826  1.00 109.48 ? 389 ILE C CA  1 
ATOM   7949  C C   . ILE C 1 380 ? 117.819 90.416  79.447  1.00 109.48 ? 389 ILE C C   1 
ATOM   7950  O O   . ILE C 1 380 ? 117.190 90.744  80.462  1.00 109.48 ? 389 ILE C O   1 
ATOM   7951  C CB  . ILE C 1 380 ? 118.270 92.104  77.615  1.00 109.48 ? 389 ILE C CB  1 
ATOM   7952  C CG1 . ILE C 1 380 ? 119.378 92.852  76.871  1.00 109.48 ? 389 ILE C CG1 1 
ATOM   7953  C CG2 . ILE C 1 380 ? 117.178 93.065  78.057  1.00 109.48 ? 389 ILE C CG2 1 
ATOM   7954  C CD1 . ILE C 1 380 ? 119.739 92.238  75.533  1.00 109.48 ? 389 ILE C CD1 1 
ATOM   7955  N N   . ASP C 1 381 ? 117.620 89.243  78.841  1.00 105.91 ? 390 ASP C N   1 
ATOM   7956  C CA  . ASP C 1 381 ? 116.666 88.282  79.382  1.00 105.91 ? 390 ASP C CA  1 
ATOM   7957  C C   . ASP C 1 381 ? 117.096 87.796  80.760  1.00 105.91 ? 390 ASP C C   1 
ATOM   7958  O O   . ASP C 1 381 ? 116.267 87.673  81.669  1.00 105.91 ? 390 ASP C O   1 
ATOM   7959  C CB  . ASP C 1 381 ? 116.505 87.104  78.421  1.00 105.91 ? 390 ASP C CB  1 
ATOM   7960  C CG  . ASP C 1 381 ? 115.215 86.340  78.646  1.00 105.91 ? 390 ASP C CG  1 
ATOM   7961  O OD1 . ASP C 1 381 ? 114.428 86.746  79.526  1.00 105.91 ? 390 ASP C OD1 1 
ATOM   7962  O OD2 . ASP C 1 381 ? 114.987 85.334  77.942  1.00 105.91 ? 390 ASP C OD2 1 
ATOM   7963  N N   . ARG C 1 382 ? 118.390 87.515  80.934  1.00 101.99 ? 391 ARG C N   1 
ATOM   7964  C CA  . ARG C 1 382 ? 118.887 87.103  82.243  1.00 101.99 ? 391 ARG C CA  1 
ATOM   7965  C C   . ARG C 1 382 ? 118.713 88.213  83.271  1.00 101.99 ? 391 ARG C C   1 
ATOM   7966  O O   . ARG C 1 382 ? 118.359 87.950  84.427  1.00 101.99 ? 391 ARG C O   1 
ATOM   7967  C CB  . ARG C 1 382 ? 120.355 86.689  82.142  1.00 101.99 ? 391 ARG C CB  1 
ATOM   7968  C CG  . ARG C 1 382 ? 121.003 86.370  83.480  1.00 101.99 ? 391 ARG C CG  1 
ATOM   7969  C CD  . ARG C 1 382 ? 122.137 85.370  83.325  1.00 101.99 ? 391 ARG C CD  1 
ATOM   7970  N NE  . ARG C 1 382 ? 123.107 85.791  82.321  1.00 101.99 ? 391 ARG C NE  1 
ATOM   7971  C CZ  . ARG C 1 382 ? 124.161 85.075  81.952  1.00 101.99 ? 391 ARG C CZ  1 
ATOM   7972  N NH1 . ARG C 1 382 ? 124.416 83.893  82.488  1.00 101.99 ? 391 ARG C NH1 1 
ATOM   7973  N NH2 . ARG C 1 382 ? 124.979 85.558  81.021  1.00 101.99 ? 391 ARG C NH2 1 
ATOM   7974  N N   . ALA C 1 383 ? 118.960 89.463  82.869  1.00 94.29  ? 392 ALA C N   1 
ATOM   7975  C CA  . ALA C 1 383 ? 118.772 90.585  83.782  1.00 94.29  ? 392 ALA C CA  1 
ATOM   7976  C C   . ALA C 1 383 ? 117.317 90.709  84.211  1.00 94.29  ? 392 ALA C C   1 
ATOM   7977  O O   . ALA C 1 383 ? 117.026 90.905  85.397  1.00 94.29  ? 392 ALA C O   1 
ATOM   7978  C CB  . ALA C 1 383 ? 119.249 91.879  83.124  1.00 94.29  ? 392 ALA C CB  1 
ATOM   7979  N N   . LYS C 1 384 ? 116.388 90.590  83.261  1.00 93.69  ? 393 LYS C N   1 
ATOM   7980  C CA  . LYS C 1 384 ? 114.971 90.670  83.603  1.00 93.69  ? 393 LYS C CA  1 
ATOM   7981  C C   . LYS C 1 384 ? 114.557 89.512  84.502  1.00 93.69  ? 393 LYS C C   1 
ATOM   7982  O O   . LYS C 1 384 ? 113.766 89.691  85.438  1.00 93.69  ? 393 LYS C O   1 
ATOM   7983  C CB  . LYS C 1 384 ? 114.123 90.695  82.331  1.00 93.69  ? 393 LYS C CB  1 
ATOM   7984  C CG  . LYS C 1 384 ? 112.627 90.787  82.581  1.00 93.69  ? 393 LYS C CG  1 
ATOM   7985  C CD  . LYS C 1 384 ? 111.929 89.472  82.274  1.00 93.69  ? 393 LYS C CD  1 
ATOM   7986  C CE  . LYS C 1 384 ? 110.428 89.582  82.489  1.00 93.69  ? 393 LYS C CE  1 
ATOM   7987  N NZ  . LYS C 1 384 ? 109.729 88.303  82.188  1.00 93.69  ? 393 LYS C NZ  1 
ATOM   7988  N N   . LYS C 1 385 ? 115.080 88.313  84.232  1.00 94.98  ? 394 LYS C N   1 
ATOM   7989  C CA  . LYS C 1 385 ? 114.762 87.162  85.069  1.00 94.98  ? 394 LYS C CA  1 
ATOM   7990  C C   . LYS C 1 385 ? 115.271 87.356  86.491  1.00 94.98  ? 394 LYS C C   1 
ATOM   7991  O O   . LYS C 1 385 ? 114.564 87.051  87.457  1.00 94.98  ? 394 LYS C O   1 
ATOM   7992  C CB  . LYS C 1 385 ? 115.344 85.889  84.455  1.00 94.98  ? 394 LYS C CB  1 
ATOM   7993  C CG  . LYS C 1 385 ? 114.573 85.383  83.246  1.00 94.98  ? 394 LYS C CG  1 
ATOM   7994  C CD  . LYS C 1 385 ? 115.370 84.352  82.464  1.00 94.98  ? 394 LYS C CD  1 
ATOM   7995  C CE  . LYS C 1 385 ? 115.465 83.036  83.217  1.00 94.98  ? 394 LYS C CE  1 
ATOM   7996  N NZ  . LYS C 1 385 ? 116.146 81.986  82.410  1.00 94.98  ? 394 LYS C NZ  1 
ATOM   7997  N N   . ILE C 1 386 ? 116.493 87.869  86.645  1.00 88.96  ? 395 ILE C N   1 
ATOM   7998  C CA  . ILE C 1 386 ? 117.024 88.091  87.986  1.00 88.96  ? 395 ILE C CA  1 
ATOM   7999  C C   . ILE C 1 386 ? 116.247 89.200  88.690  1.00 88.96  ? 395 ILE C C   1 
ATOM   8000  O O   . ILE C 1 386 ? 116.008 89.135  89.903  1.00 88.96  ? 395 ILE C O   1 
ATOM   8001  C CB  . ILE C 1 386 ? 118.541 88.372  87.931  1.00 88.96  ? 395 ILE C CB  1 
ATOM   8002  C CG1 . ILE C 1 386 ? 119.234 87.778  89.158  1.00 88.96  ? 395 ILE C CG1 1 
ATOM   8003  C CG2 . ILE C 1 386 ? 118.848 89.860  87.831  1.00 88.96  ? 395 ILE C CG2 1 
ATOM   8004  C CD1 . ILE C 1 386 ? 119.030 86.287  89.311  1.00 88.96  ? 395 ILE C CD1 1 
ATOM   8005  N N   . ASP C 1 387 ? 115.809 90.216  87.940  1.00 87.97  ? 396 ASP C N   1 
ATOM   8006  C CA  . ASP C 1 387 ? 115.029 91.293  88.540  1.00 87.97  ? 396 ASP C CA  1 
ATOM   8007  C C   . ASP C 1 387 ? 113.690 90.779  89.051  1.00 87.97  ? 396 ASP C C   1 
ATOM   8008  O O   . ASP C 1 387 ? 113.278 91.098  90.172  1.00 87.97  ? 396 ASP C O   1 
ATOM   8009  C CB  . ASP C 1 387 ? 114.826 92.420  87.528  1.00 87.97  ? 396 ASP C CB  1 
ATOM   8010  N N   . THR C 1 388 ? 112.998 89.967  88.247  1.00 94.86  ? 397 THR C N   1 
ATOM   8011  C CA  . THR C 1 388 ? 111.718 89.435  88.703  1.00 94.86  ? 397 THR C CA  1 
ATOM   8012  C C   . THR C 1 388 ? 111.908 88.406  89.811  1.00 94.86  ? 397 THR C C   1 
ATOM   8013  O O   . THR C 1 388 ? 111.048 88.282  90.690  1.00 94.86  ? 397 THR C O   1 
ATOM   8014  C CB  . THR C 1 388 ? 110.923 88.846  87.532  1.00 94.86  ? 397 THR C CB  1 
ATOM   8015  O OG1 . THR C 1 388 ? 109.580 88.575  87.954  1.00 94.86  ? 397 THR C OG1 1 
ATOM   8016  C CG2 . THR C 1 388 ? 111.549 87.561  87.021  1.00 94.86  ? 397 THR C CG2 1 
ATOM   8017  N N   . ILE C 1 389 ? 113.036 87.690  89.816  1.00 93.86  ? 398 ILE C N   1 
ATOM   8018  C CA  . ILE C 1 389 ? 113.330 86.780  90.918  1.00 93.86  ? 398 ILE C CA  1 
ATOM   8019  C C   . ILE C 1 389 ? 113.487 87.558  92.217  1.00 93.86  ? 398 ILE C C   1 
ATOM   8020  O O   . ILE C 1 389 ? 112.945 87.172  93.259  1.00 93.86  ? 398 ILE C O   1 
ATOM   8021  C CB  . ILE C 1 389 ? 114.584 85.944  90.603  1.00 93.86  ? 398 ILE C CB  1 
ATOM   8022  N N   . SER C 1 390 ? 114.226 88.669  92.176  1.00 94.12  ? 399 SER C N   1 
ATOM   8023  C CA  . SER C 1 390 ? 114.364 89.503  93.366  1.00 94.12  ? 399 SER C CA  1 
ATOM   8024  C C   . SER C 1 390 ? 113.020 90.081  93.794  1.00 94.12  ? 399 SER C C   1 
ATOM   8025  O O   . SER C 1 390 ? 112.695 90.108  94.989  1.00 94.12  ? 399 SER C O   1 
ATOM   8026  C CB  . SER C 1 390 ? 115.372 90.623  93.108  1.00 94.12  ? 399 SER C CB  1 
ATOM   8027  N N   . ARG C 1 391 ? 112.222 90.545  92.827  1.00 93.79  ? 400 ARG C N   1 
ATOM   8028  C CA  . ARG C 1 391 ? 110.932 91.148  93.148  1.00 93.79  ? 400 ARG C CA  1 
ATOM   8029  C C   . ARG C 1 391 ? 109.950 90.128  93.711  1.00 93.79  ? 400 ARG C C   1 
ATOM   8030  O O   . ARG C 1 391 ? 109.024 90.501  94.439  1.00 93.79  ? 400 ARG C O   1 
ATOM   8031  C CB  . ARG C 1 391 ? 110.344 91.819  91.908  1.00 93.79  ? 400 ARG C CB  1 
ATOM   8032  N N   . ALA C 1 392 ? 110.118 88.850  93.375  1.00 94.85  ? 401 ALA C N   1 
ATOM   8033  C CA  . ALA C 1 392 ? 109.274 87.805  93.937  1.00 94.85  ? 401 ALA C CA  1 
ATOM   8034  C C   . ALA C 1 392 ? 109.841 87.202  95.213  1.00 94.85  ? 401 ALA C C   1 
ATOM   8035  O O   . ALA C 1 392 ? 109.103 86.537  95.949  1.00 94.85  ? 401 ALA C O   1 
ATOM   8036  C CB  . ALA C 1 392 ? 109.053 86.692  92.909  1.00 94.85  ? 401 ALA C CB  1 
ATOM   8037  N N   . CYS C 1 393 ? 111.127 87.411  95.489  1.00 96.95  ? 402 CYS C N   1 
ATOM   8038  C CA  . CYS C 1 393 ? 111.757 86.837  96.672  1.00 96.95  ? 402 CYS C CA  1 
ATOM   8039  C C   . CYS C 1 393 ? 111.725 87.781  97.869  1.00 96.95  ? 402 CYS C C   1 
ATOM   8040  O O   . CYS C 1 393 ? 111.356 87.368  98.972  1.00 96.95  ? 402 CYS C O   1 
ATOM   8041  C CB  . CYS C 1 393 ? 113.204 86.448  96.352  1.00 96.95  ? 402 CYS C CB  1 
ATOM   8042  S SG  . CYS C 1 393 ? 114.202 86.022  97.798  1.00 96.95  ? 402 CYS C SG  1 
ATOM   8043  N N   . PHE C 1 394 ? 112.112 89.043  97.669  1.00 90.99  ? 403 PHE C N   1 
ATOM   8044  C CA  . PHE C 1 394 ? 112.248 89.963  98.799  1.00 90.99  ? 403 PHE C CA  1 
ATOM   8045  C C   . PHE C 1 394 ? 110.957 90.156  99.586  1.00 90.99  ? 403 PHE C C   1 
ATOM   8046  O O   . PHE C 1 394 ? 111.009 90.107  100.828 1.00 90.99  ? 403 PHE C O   1 
ATOM   8047  C CB  . PHE C 1 394 ? 112.808 91.302  98.307  1.00 90.99  ? 403 PHE C CB  1 
ATOM   8048  C CG  . PHE C 1 394 ? 114.306 91.337  98.227  1.00 90.99  ? 403 PHE C CG  1 
ATOM   8049  C CD1 . PHE C 1 394 ? 115.069 90.403  98.905  1.00 90.99  ? 403 PHE C CD1 1 
ATOM   8050  C CD2 . PHE C 1 394 ? 114.950 92.297  97.468  1.00 90.99  ? 403 PHE C CD2 1 
ATOM   8051  C CE1 . PHE C 1 394 ? 116.447 90.431  98.832  1.00 90.99  ? 403 PHE C CE1 1 
ATOM   8052  C CE2 . PHE C 1 394 ? 116.326 92.330  97.390  1.00 90.99  ? 403 PHE C CE2 1 
ATOM   8053  C CZ  . PHE C 1 394 ? 117.076 91.396  98.072  1.00 90.99  ? 403 PHE C CZ  1 
ATOM   8054  N N   . PRO C 1 395 ? 109.793 90.399  98.966  1.00 88.71  ? 404 PRO C N   1 
ATOM   8055  C CA  . PRO C 1 395 ? 108.572 90.533  99.779  1.00 88.71  ? 404 PRO C CA  1 
ATOM   8056  C C   . PRO C 1 395 ? 108.264 89.305  100.614 1.00 88.71  ? 404 PRO C C   1 
ATOM   8057  O O   . PRO C 1 395 ? 107.870 89.440  101.778 1.00 88.71  ? 404 PRO C O   1 
ATOM   8058  C CB  . PRO C 1 395 ? 107.483 90.797  98.730  1.00 88.71  ? 404 PRO C CB  1 
ATOM   8059  C CG  . PRO C 1 395 ? 108.208 91.371  97.575  1.00 88.71  ? 404 PRO C CG  1 
ATOM   8060  C CD  . PRO C 1 395 ? 109.521 90.658  97.542  1.00 88.71  ? 404 PRO C CD  1 
ATOM   8061  N N   . LEU C 1 396 ? 108.452 88.104  100.063 1.00 85.88  ? 405 LEU C N   1 
ATOM   8062  C CA  . LEU C 1 396 ? 108.191 86.896  100.838 1.00 85.88  ? 405 LEU C CA  1 
ATOM   8063  C C   . LEU C 1 396 ? 109.190 86.747  101.977 1.00 85.88  ? 405 LEU C C   1 
ATOM   8064  O O   . LEU C 1 396 ? 108.824 86.319  103.079 1.00 85.88  ? 405 LEU C O   1 
ATOM   8065  C CB  . LEU C 1 396 ? 108.223 85.667  99.932  1.00 85.88  ? 405 LEU C CB  1 
ATOM   8066  C CG  . LEU C 1 396 ? 107.706 84.378  100.573 1.00 85.88  ? 405 LEU C CG  1 
ATOM   8067  C CD1 . LEU C 1 396 ? 106.735 83.666  99.645  1.00 85.88  ? 405 LEU C CD1 1 
ATOM   8068  C CD2 . LEU C 1 396 ? 108.862 83.463  100.949 1.00 85.88  ? 405 LEU C CD2 1 
ATOM   8069  N N   . ALA C 1 397 ? 110.457 87.086  101.728 1.00 87.49  ? 406 ALA C N   1 
ATOM   8070  C CA  . ALA C 1 397 ? 111.457 87.029  102.788 1.00 87.49  ? 406 ALA C CA  1 
ATOM   8071  C C   . ALA C 1 397 ? 111.105 87.980  103.923 1.00 87.49  ? 406 ALA C C   1 
ATOM   8072  O O   . ALA C 1 397 ? 111.200 87.617  105.102 1.00 87.49  ? 406 ALA C O   1 
ATOM   8073  C CB  . ALA C 1 397 ? 112.841 87.351  102.226 1.00 87.49  ? 406 ALA C CB  1 
ATOM   8074  N N   . PHE C 1 398 ? 110.682 89.201  103.591 1.00 81.43  ? 407 PHE C N   1 
ATOM   8075  C CA  . PHE C 1 398 ? 110.301 90.134  104.644 1.00 81.43  ? 407 PHE C CA  1 
ATOM   8076  C C   . PHE C 1 398 ? 109.050 89.653  105.366 1.00 81.43  ? 407 PHE C C   1 
ATOM   8077  O O   . PHE C 1 398 ? 108.961 89.771  106.589 1.00 81.43  ? 407 PHE C O   1 
ATOM   8078  C CB  . PHE C 1 398 ? 110.121 91.540  104.064 1.00 81.43  ? 407 PHE C CB  1 
ATOM   8079  C CG  . PHE C 1 398 ? 110.081 92.651  105.101 1.00 81.43  ? 407 PHE C CG  1 
ATOM   8080  C CD1 . PHE C 1 398 ? 109.225 92.610  106.191 1.00 81.43  ? 407 PHE C CD1 1 
ATOM   8081  C CD2 . PHE C 1 398 ? 110.951 93.721  104.998 1.00 81.43  ? 407 PHE C CD2 1 
ATOM   8082  C CE1 . PHE C 1 398 ? 109.213 93.624  107.129 1.00 81.43  ? 407 PHE C CE1 1 
ATOM   8083  C CE2 . PHE C 1 398 ? 110.946 94.736  105.935 1.00 81.43  ? 407 PHE C CE2 1 
ATOM   8084  C CZ  . PHE C 1 398 ? 110.076 94.687  107.000 1.00 81.43  ? 407 PHE C CZ  1 
ATOM   8085  N N   . LEU C 1 399 ? 108.084 89.090  104.640 1.00 78.55  ? 408 LEU C N   1 
ATOM   8086  C CA  . LEU C 1 399 ? 106.874 88.601  105.295 1.00 78.55  ? 408 LEU C CA  1 
ATOM   8087  C C   . LEU C 1 399 ? 107.199 87.492  106.289 1.00 78.55  ? 408 LEU C C   1 
ATOM   8088  O O   . LEU C 1 399 ? 106.713 87.499  107.430 1.00 78.55  ? 408 LEU C O   1 
ATOM   8089  C CB  . LEU C 1 399 ? 105.872 88.112  104.248 1.00 78.55  ? 408 LEU C CB  1 
ATOM   8090  C CG  . LEU C 1 399 ? 104.417 87.981  104.703 1.00 78.55  ? 408 LEU C CG  1 
ATOM   8091  C CD1 . LEU C 1 399 ? 103.472 88.481  103.623 1.00 78.55  ? 408 LEU C CD1 1 
ATOM   8092  C CD2 . LEU C 1 399 ? 104.091 86.544  105.075 1.00 78.55  ? 408 LEU C CD2 1 
ATOM   8093  N N   . ILE C 1 400 ? 108.037 86.535  105.882 1.00 77.40  ? 409 ILE C N   1 
ATOM   8094  C CA  . ILE C 1 400 ? 108.355 85.428  106.776 1.00 77.40  ? 409 ILE C CA  1 
ATOM   8095  C C   . ILE C 1 400 ? 109.187 85.916  107.957 1.00 77.40  ? 409 ILE C C   1 
ATOM   8096  O O   . ILE C 1 400 ? 108.954 85.506  109.100 1.00 77.40  ? 409 ILE C O   1 
ATOM   8097  C CB  . ILE C 1 400 ? 109.040 84.274  106.017 1.00 77.40  ? 409 ILE C CB  1 
ATOM   8098  C CG1 . ILE C 1 400 ? 109.225 83.068  106.943 1.00 77.40  ? 409 ILE C CG1 1 
ATOM   8099  C CG2 . ILE C 1 400 ? 110.374 84.691  105.430 1.00 77.40  ? 409 ILE C CG2 1 
ATOM   8100  C CD1 . ILE C 1 400 ? 109.942 81.904  106.298 1.00 77.40  ? 409 ILE C CD1 1 
ATOM   8101  N N   . PHE C 1 401 ? 110.145 86.820  107.717 1.00 72.92  ? 410 PHE C N   1 
ATOM   8102  C CA  . PHE C 1 401 ? 110.910 87.367  108.833 1.00 72.92  ? 410 PHE C CA  1 
ATOM   8103  C C   . PHE C 1 401 ? 110.010 88.123  109.799 1.00 72.92  ? 410 PHE C C   1 
ATOM   8104  O O   . PHE C 1 401 ? 110.163 88.009  111.018 1.00 72.92  ? 410 PHE C O   1 
ATOM   8105  C CB  . PHE C 1 401 ? 112.016 88.296  108.339 1.00 72.92  ? 410 PHE C CB  1 
ATOM   8106  C CG  . PHE C 1 401 ? 112.373 89.364  109.334 1.00 72.92  ? 410 PHE C CG  1 
ATOM   8107  C CD1 . PHE C 1 401 ? 113.148 89.064  110.440 1.00 72.92  ? 410 PHE C CD1 1 
ATOM   8108  C CD2 . PHE C 1 401 ? 111.902 90.658  109.184 1.00 72.92  ? 410 PHE C CD2 1 
ATOM   8109  C CE1 . PHE C 1 401 ? 113.461 90.036  111.367 1.00 72.92  ? 410 PHE C CE1 1 
ATOM   8110  C CE2 . PHE C 1 401 ? 112.212 91.633  110.108 1.00 72.92  ? 410 PHE C CE2 1 
ATOM   8111  C CZ  . PHE C 1 401 ? 112.991 91.321  111.202 1.00 72.92  ? 410 PHE C CZ  1 
ATOM   8112  N N   . ASN C 1 402 ? 109.088 88.925  109.269 1.00 74.81  ? 411 ASN C N   1 
ATOM   8113  C CA  . ASN C 1 402 ? 108.208 89.723  110.110 1.00 74.81  ? 411 ASN C CA  1 
ATOM   8114  C C   . ASN C 1 402 ? 107.344 88.830  110.984 1.00 74.81  ? 411 ASN C C   1 
ATOM   8115  O O   . ASN C 1 402 ? 107.253 89.033  112.201 1.00 74.81  ? 411 ASN C O   1 
ATOM   8116  C CB  . ASN C 1 402 ? 107.341 90.627  109.233 1.00 74.81  ? 411 ASN C CB  1 
ATOM   8117  C CG  . ASN C 1 402 ? 106.452 91.548  110.038 1.00 74.81  ? 411 ASN C CG  1 
ATOM   8118  O OD1 . ASN C 1 402 ? 106.931 92.324  110.861 1.00 74.81  ? 411 ASN C OD1 1 
ATOM   8119  N ND2 . ASN C 1 402 ? 105.148 91.465  109.805 1.00 74.81  ? 411 ASN C ND2 1 
ATOM   8120  N N   . ILE C 1 403 ? 106.716 87.816  110.383 1.00 73.15  ? 412 ILE C N   1 
ATOM   8121  C CA  . ILE C 1 403 ? 105.857 86.934  111.167 1.00 73.15  ? 412 ILE C CA  1 
ATOM   8122  C C   . ILE C 1 403 ? 106.682 86.159  112.191 1.00 73.15  ? 412 ILE C C   1 
ATOM   8123  O O   . ILE C 1 403 ? 106.269 86.008  113.349 1.00 73.15  ? 412 ILE C O   1 
ATOM   8124  C CB  . ILE C 1 403 ? 105.033 86.011  110.245 1.00 73.15  ? 412 ILE C CB  1 
ATOM   8125  C CG1 . ILE C 1 403 ? 103.846 85.419  111.010 1.00 73.15  ? 412 ILE C CG1 1 
ATOM   8126  C CG2 . ILE C 1 403 ? 105.882 84.913  109.620 1.00 73.15  ? 412 ILE C CG2 1 
ATOM   8127  C CD1 . ILE C 1 403 ? 102.966 86.458  111.672 1.00 73.15  ? 412 ILE C CD1 1 
ATOM   8128  N N   . PHE C 1 404 ? 107.881 85.708  111.805 1.00 75.14  ? 413 PHE C N   1 
ATOM   8129  C CA  . PHE C 1 404 ? 108.723 84.956  112.729 1.00 75.14  ? 413 PHE C CA  1 
ATOM   8130  C C   . PHE C 1 404 ? 109.140 85.814  113.916 1.00 75.14  ? 413 PHE C C   1 
ATOM   8131  O O   . PHE C 1 404 ? 108.999 85.403  115.073 1.00 75.14  ? 413 PHE C O   1 
ATOM   8132  C CB  . PHE C 1 404 ? 109.951 84.424  111.990 1.00 75.14  ? 413 PHE C CB  1 
ATOM   8133  C CG  . PHE C 1 404 ? 110.490 83.142  112.552 1.00 75.14  ? 413 PHE C CG  1 
ATOM   8134  C CD1 . PHE C 1 404 ? 109.636 82.183  113.067 1.00 75.14  ? 413 PHE C CD1 1 
ATOM   8135  C CD2 . PHE C 1 404 ? 111.852 82.895  112.562 1.00 75.14  ? 413 PHE C CD2 1 
ATOM   8136  C CE1 . PHE C 1 404 ? 110.130 81.001  113.585 1.00 75.14  ? 413 PHE C CE1 1 
ATOM   8137  C CE2 . PHE C 1 404 ? 112.352 81.715  113.077 1.00 75.14  ? 413 PHE C CE2 1 
ATOM   8138  C CZ  . PHE C 1 404 ? 111.490 80.767  113.589 1.00 75.14  ? 413 PHE C CZ  1 
ATOM   8139  N N   . TYR C 1 405 ? 109.654 87.016  113.643 1.00 70.02  ? 414 TYR C N   1 
ATOM   8140  C CA  . TYR C 1 405 ? 110.116 87.904  114.704 1.00 70.02  ? 414 TYR C CA  1 
ATOM   8141  C C   . TYR C 1 405 ? 108.972 88.299  115.626 1.00 70.02  ? 414 TYR C C   1 
ATOM   8142  O O   . TYR C 1 405 ? 109.113 88.268  116.858 1.00 70.02  ? 414 TYR C O   1 
ATOM   8143  C CB  . TYR C 1 405 ? 110.780 89.133  114.078 1.00 70.02  ? 414 TYR C CB  1 
ATOM   8144  C CG  . TYR C 1 405 ? 110.791 90.392  114.920 1.00 70.02  ? 414 TYR C CG  1 
ATOM   8145  C CD1 . TYR C 1 405 ? 111.841 90.663  115.784 1.00 70.02  ? 414 TYR C CD1 1 
ATOM   8146  C CD2 . TYR C 1 405 ? 109.770 91.328  114.819 1.00 70.02  ? 414 TYR C CD2 1 
ATOM   8147  C CE1 . TYR C 1 405 ? 111.863 91.817  116.541 1.00 70.02  ? 414 TYR C CE1 1 
ATOM   8148  C CE2 . TYR C 1 405 ? 109.783 92.482  115.573 1.00 70.02  ? 414 TYR C CE2 1 
ATOM   8149  C CZ  . TYR C 1 405 ? 110.831 92.723  116.431 1.00 70.02  ? 414 TYR C CZ  1 
ATOM   8150  O OH  . TYR C 1 405 ? 110.846 93.875  117.183 1.00 70.02  ? 414 TYR C OH  1 
ATOM   8151  N N   . TRP C 1 406 ? 107.820 88.653  115.050 1.00 73.96  ? 415 TRP C N   1 
ATOM   8152  C CA  . TRP C 1 406 ? 106.680 89.029  115.874 1.00 73.96  ? 415 TRP C CA  1 
ATOM   8153  C C   . TRP C 1 406 ? 106.257 87.879  116.773 1.00 73.96  ? 415 TRP C C   1 
ATOM   8154  O O   . TRP C 1 406 ? 106.055 88.069  117.977 1.00 73.96  ? 415 TRP C O   1 
ATOM   8155  C CB  . TRP C 1 406 ? 105.516 89.484  114.996 1.00 73.96  ? 415 TRP C CB  1 
ATOM   8156  C CG  . TRP C 1 406 ? 105.603 90.916  114.563 1.00 73.96  ? 415 TRP C CG  1 
ATOM   8157  C CD1 . TRP C 1 406 ? 105.575 91.382  113.285 1.00 73.96  ? 415 TRP C CD1 1 
ATOM   8158  C CD2 . TRP C 1 406 ? 105.728 92.068  115.407 1.00 73.96  ? 415 TRP C CD2 1 
ATOM   8159  N NE1 . TRP C 1 406 ? 105.677 92.751  113.275 1.00 73.96  ? 415 TRP C NE1 1 
ATOM   8160  C CE2 . TRP C 1 406 ? 105.772 93.196  114.567 1.00 73.96  ? 415 TRP C CE2 1 
ATOM   8161  C CE3 . TRP C 1 406 ? 105.807 92.254  116.789 1.00 73.96  ? 415 TRP C CE3 1 
ATOM   8162  C CZ2 . TRP C 1 406 ? 105.891 94.490  115.062 1.00 73.96  ? 415 TRP C CZ2 1 
ATOM   8163  C CZ3 . TRP C 1 406 ? 105.925 93.540  117.279 1.00 73.96  ? 415 TRP C CZ3 1 
ATOM   8164  C CH2 . TRP C 1 406 ? 105.967 94.641  116.418 1.00 73.96  ? 415 TRP C CH2 1 
ATOM   8165  N N   . VAL C 1 407 ? 106.147 86.666  116.221 1.00 77.09  ? 416 VAL C N   1 
ATOM   8166  C CA  . VAL C 1 407 ? 105.665 85.563  117.046 1.00 77.09  ? 416 VAL C CA  1 
ATOM   8167  C C   . VAL C 1 407 ? 106.667 85.235  118.150 1.00 77.09  ? 416 VAL C C   1 
ATOM   8168  O O   . VAL C 1 407 ? 106.278 85.081  119.316 1.00 77.09  ? 416 VAL C O   1 
ATOM   8169  C CB  . VAL C 1 407 ? 105.308 84.332  116.187 1.00 77.09  ? 416 VAL C CB  1 
ATOM   8170  C CG1 . VAL C 1 407 ? 106.525 83.714  115.527 1.00 77.09  ? 416 VAL C CG1 1 
ATOM   8171  C CG2 . VAL C 1 407 ? 104.584 83.297  117.035 1.00 77.09  ? 416 VAL C CG2 1 
ATOM   8172  N N   . ILE C 1 408 ? 107.969 85.177  117.831 1.00 76.42  ? 417 ILE C N   1 
ATOM   8173  C CA  . ILE C 1 408 ? 108.938 84.801  118.861 1.00 76.42  ? 417 ILE C CA  1 
ATOM   8174  C C   . ILE C 1 408 ? 108.938 85.837  119.977 1.00 76.42  ? 417 ILE C C   1 
ATOM   8175  O O   . ILE C 1 408 ? 108.738 85.500  121.151 1.00 76.42  ? 417 ILE C O   1 
ATOM   8176  C CB  . ILE C 1 408 ? 110.351 84.605  118.272 1.00 76.42  ? 417 ILE C CB  1 
ATOM   8177  C CG1 . ILE C 1 408 ? 111.411 84.564  119.378 1.00 76.42  ? 417 ILE C CG1 1 
ATOM   8178  C CG2 . ILE C 1 408 ? 110.756 85.738  117.389 1.00 76.42  ? 417 ILE C CG2 1 
ATOM   8179  C CD1 . ILE C 1 408 ? 111.259 83.437  120.367 1.00 76.42  ? 417 ILE C CD1 1 
ATOM   8180  N N   . TYR C 1 409 ? 109.068 87.116  119.623 1.00 71.13  ? 418 TYR C N   1 
ATOM   8181  C CA  . TYR C 1 409 ? 109.248 88.141  120.638 1.00 71.13  ? 418 TYR C CA  1 
ATOM   8182  C C   . TYR C 1 409 ? 107.934 88.678  121.183 1.00 71.13  ? 418 TYR C C   1 
ATOM   8183  O O   . TYR C 1 409 ? 107.952 89.607  121.996 1.00 71.13  ? 418 TYR C O   1 
ATOM   8184  C CB  . TYR C 1 409 ? 110.100 89.282  120.079 1.00 71.13  ? 418 TYR C CB  1 
ATOM   8185  C CG  . TYR C 1 409 ? 111.558 89.139  120.448 1.00 71.13  ? 418 TYR C CG  1 
ATOM   8186  C CD1 . TYR C 1 409 ? 112.230 87.946  120.235 1.00 71.13  ? 418 TYR C CD1 1 
ATOM   8187  C CD2 . TYR C 1 409 ? 112.254 90.184  121.023 1.00 71.13  ? 418 TYR C CD2 1 
ATOM   8188  C CE1 . TYR C 1 409 ? 113.562 87.804  120.576 1.00 71.13  ? 418 TYR C CE1 1 
ATOM   8189  C CE2 . TYR C 1 409 ? 113.587 90.058  121.362 1.00 71.13  ? 418 TYR C CE2 1 
ATOM   8190  C CZ  . TYR C 1 409 ? 114.236 88.864  121.140 1.00 71.13  ? 418 TYR C CZ  1 
ATOM   8191  O OH  . TYR C 1 409 ? 115.561 88.729  121.482 1.00 71.13  ? 418 TYR C OH  1 
ATOM   8192  N N   . LYS C 1 410 ? 106.799 88.116  120.769 1.00 77.40  ? 419 LYS C N   1 
ATOM   8193  C CA  . LYS C 1 410 ? 105.523 88.440  121.386 1.00 77.40  ? 419 LYS C CA  1 
ATOM   8194  C C   . LYS C 1 410 ? 104.951 87.315  122.232 1.00 77.40  ? 419 LYS C C   1 
ATOM   8195  O O   . LYS C 1 410 ? 104.275 87.597  123.222 1.00 77.40  ? 419 LYS C O   1 
ATOM   8196  C CB  . LYS C 1 410 ? 104.498 88.826  120.313 1.00 77.40  ? 419 LYS C CB  1 
ATOM   8197  C CG  . LYS C 1 410 ? 103.198 89.386  120.864 1.00 77.40  ? 419 LYS C CG  1 
ATOM   8198  C CD  . LYS C 1 410 ? 103.444 90.649  121.671 1.00 77.40  ? 419 LYS C CD  1 
ATOM   8199  C CE  . LYS C 1 410 ? 103.926 91.784  120.784 1.00 77.40  ? 419 LYS C CE  1 
ATOM   8200  N NZ  . LYS C 1 410 ? 102.978 92.054  119.669 1.00 77.40  ? 419 LYS C NZ  1 
ATOM   8201  N N   . ILE C 1 411 ? 105.204 86.049  121.888 1.00 86.08  ? 420 ILE C N   1 
ATOM   8202  C CA  . ILE C 1 411 ? 104.661 84.916  122.626 1.00 86.08  ? 420 ILE C CA  1 
ATOM   8203  C C   . ILE C 1 411 ? 105.767 84.039  123.202 1.00 86.08  ? 420 ILE C C   1 
ATOM   8204  O O   . ILE C 1 411 ? 105.726 83.664  124.378 1.00 86.08  ? 420 ILE C O   1 
ATOM   8205  C CB  . ILE C 1 411 ? 103.702 84.080  121.749 1.00 86.08  ? 420 ILE C CB  1 
ATOM   8206  C CG1 . ILE C 1 411 ? 102.563 84.956  121.221 1.00 86.08  ? 420 ILE C CG1 1 
ATOM   8207  C CG2 . ILE C 1 411 ? 103.147 82.904  122.537 1.00 86.08  ? 420 ILE C CG2 1 
ATOM   8208  C CD1 . ILE C 1 411 ? 101.538 84.203  120.403 1.00 86.08  ? 420 ILE C CD1 1 
ATOM   8209  N N   . LEU C 1 412 ? 106.769 83.706  122.391 1.00 88.03  ? 421 LEU C N   1 
ATOM   8210  C CA  . LEU C 1 412 ? 107.755 82.720  122.811 1.00 88.03  ? 421 LEU C CA  1 
ATOM   8211  C C   . LEU C 1 412 ? 108.876 83.321  123.647 1.00 88.03  ? 421 LEU C C   1 
ATOM   8212  O O   . LEU C 1 412 ? 109.749 82.577  124.107 1.00 88.03  ? 421 LEU C O   1 
ATOM   8213  C CB  . LEU C 1 412 ? 108.336 82.012  121.585 1.00 88.03  ? 421 LEU C CB  1 
ATOM   8214  C CG  . LEU C 1 412 ? 108.729 80.542  121.745 1.00 88.03  ? 421 LEU C CG  1 
ATOM   8215  C CD1 . LEU C 1 412 ? 107.500 79.682  122.001 1.00 88.03  ? 421 LEU C CD1 1 
ATOM   8216  C CD2 . LEU C 1 412 ? 109.489 80.054  120.521 1.00 88.03  ? 421 LEU C CD2 1 
ATOM   8217  N N   . ARG C 1 413 ? 108.875 84.633  123.855 1.00 86.67  ? 422 ARG C N   1 
ATOM   8218  C CA  . ARG C 1 413 ? 109.890 85.278  124.678 1.00 86.67  ? 422 ARG C CA  1 
ATOM   8219  C C   . ARG C 1 413 ? 109.259 86.320  125.594 1.00 86.67  ? 422 ARG C C   1 
ATOM   8220  O O   . ARG C 1 413 ? 108.188 86.095  126.158 1.00 86.67  ? 422 ARG C O   1 
ATOM   8221  C CB  . ARG C 1 413 ? 110.964 85.925  123.801 1.00 86.67  ? 422 ARG C CB  1 
ATOM   8222  N N   . MET D 1 8   ? 116.334 101.296 188.711 1.00 78.36  ? 8   MET D N   1 
ATOM   8223  C CA  . MET D 1 8   ? 115.873 100.126 187.974 1.00 78.36  ? 8   MET D CA  1 
ATOM   8224  C C   . MET D 1 8   ? 115.066 100.540 186.750 1.00 78.36  ? 8   MET D C   1 
ATOM   8225  O O   . MET D 1 8   ? 114.887 99.756  185.819 1.00 78.36  ? 8   MET D O   1 
ATOM   8226  C CB  . MET D 1 8   ? 115.037 99.219  188.878 1.00 78.36  ? 8   MET D CB  1 
ATOM   8227  C CG  . MET D 1 8   ? 115.754 98.775  190.142 1.00 78.36  ? 8   MET D CG  1 
ATOM   8228  S SD  . MET D 1 8   ? 116.146 100.152 191.237 1.00 78.36  ? 8   MET D SD  1 
ATOM   8229  C CE  . MET D 1 8   ? 114.639 100.258 192.199 1.00 78.36  ? 8   MET D CE  1 
ATOM   8230  N N   . SER D 1 9   ? 114.579 101.773 186.763 1.00 75.26  ? 9   SER D N   1 
ATOM   8231  C CA  . SER D 1 9   ? 113.831 102.288 185.624 1.00 75.26  ? 9   SER D CA  1 
ATOM   8232  C C   . SER D 1 9   ? 114.769 102.471 184.436 1.00 75.26  ? 9   SER D C   1 
ATOM   8233  O O   . SER D 1 9   ? 115.817 103.113 184.575 1.00 75.26  ? 9   SER D O   1 
ATOM   8234  C CB  . SER D 1 9   ? 113.159 103.611 185.980 1.00 75.26  ? 9   SER D CB  1 
ATOM   8235  O OG  . SER D 1 9   ? 112.441 104.131 184.874 1.00 75.26  ? 9   SER D OG  1 
ATOM   8236  N N   . PRO D 1 10  ? 114.442 101.917 183.266 1.00 68.87  ? 10  PRO D N   1 
ATOM   8237  C CA  . PRO D 1 10  ? 115.351 102.059 182.115 1.00 68.87  ? 10  PRO D CA  1 
ATOM   8238  C C   . PRO D 1 10  ? 115.616 103.503 181.727 1.00 68.87  ? 10  PRO D C   1 
ATOM   8239  O O   . PRO D 1 10  ? 116.741 103.839 181.340 1.00 68.87  ? 10  PRO D O   1 
ATOM   8240  C CB  . PRO D 1 10  ? 114.625 101.291 181.002 1.00 68.87  ? 10  PRO D CB  1 
ATOM   8241  C CG  . PRO D 1 10  ? 113.196 101.232 181.440 1.00 68.87  ? 10  PRO D CG  1 
ATOM   8242  C CD  . PRO D 1 10  ? 113.230 101.156 182.929 1.00 68.87  ? 10  PRO D CD  1 
ATOM   8243  N N   . SER D 1 11  ? 114.607 104.371 181.823 1.00 68.83  ? 11  SER D N   1 
ATOM   8244  C CA  . SER D 1 11  ? 114.827 105.786 181.539 1.00 68.83  ? 11  SER D CA  1 
ATOM   8245  C C   . SER D 1 11  ? 115.787 106.402 182.548 1.00 68.83  ? 11  SER D C   1 
ATOM   8246  O O   . SER D 1 11  ? 116.683 107.173 182.179 1.00 68.83  ? 11  SER D O   1 
ATOM   8247  C CB  . SER D 1 11  ? 113.495 106.533 181.540 1.00 68.83  ? 11  SER D CB  1 
ATOM   8248  O OG  . SER D 1 11  ? 113.669 107.879 181.139 1.00 68.83  ? 11  SER D OG  1 
ATOM   8249  N N   . ASP D 1 12  ? 115.616 106.071 183.829 1.00 74.06  ? 12  ASP D N   1 
ATOM   8250  C CA  . ASP D 1 12  ? 116.537 106.565 184.844 1.00 74.06  ? 12  ASP D CA  1 
ATOM   8251  C C   . ASP D 1 12  ? 117.936 106.001 184.636 1.00 74.06  ? 12  ASP D C   1 
ATOM   8252  O O   . ASP D 1 12  ? 118.930 106.688 184.889 1.00 74.06  ? 12  ASP D O   1 
ATOM   8253  C CB  . ASP D 1 12  ? 116.014 106.223 186.238 1.00 74.06  ? 12  ASP D CB  1 
ATOM   8254  C CG  . ASP D 1 12  ? 115.055 107.269 186.771 1.00 74.06  ? 12  ASP D CG  1 
ATOM   8255  O OD1 . ASP D 1 12  ? 115.408 108.466 186.751 1.00 74.06  ? 12  ASP D OD1 1 
ATOM   8256  O OD2 . ASP D 1 12  ? 113.947 106.894 187.207 1.00 74.06  ? 12  ASP D OD2 1 
ATOM   8257  N N   . PHE D 1 13  ? 118.035 104.753 184.171 1.00 67.87  ? 13  PHE D N   1 
ATOM   8258  C CA  . PHE D 1 13  ? 119.344 104.189 183.858 1.00 67.87  ? 13  PHE D CA  1 
ATOM   8259  C C   . PHE D 1 13  ? 120.009 104.939 182.713 1.00 67.87  ? 13  PHE D C   1 
ATOM   8260  O O   . PHE D 1 13  ? 121.212 105.220 182.761 1.00 67.87  ? 13  PHE D O   1 
ATOM   8261  C CB  . PHE D 1 13  ? 119.216 102.708 183.515 1.00 67.87  ? 13  PHE D CB  1 
ATOM   8262  C CG  . PHE D 1 13  ? 120.418 102.148 182.814 1.00 67.87  ? 13  PHE D CG  1 
ATOM   8263  C CD1 . PHE D 1 13  ? 121.624 102.019 183.479 1.00 67.87  ? 13  PHE D CD1 1 
ATOM   8264  C CD2 . PHE D 1 13  ? 120.344 101.755 181.490 1.00 67.87  ? 13  PHE D CD2 1 
ATOM   8265  C CE1 . PHE D 1 13  ? 122.732 101.506 182.839 1.00 67.87  ? 13  PHE D CE1 1 
ATOM   8266  C CE2 . PHE D 1 13  ? 121.448 101.241 180.844 1.00 67.87  ? 13  PHE D CE2 1 
ATOM   8267  C CZ  . PHE D 1 13  ? 122.643 101.116 181.520 1.00 67.87  ? 13  PHE D CZ  1 
ATOM   8268  N N   . LEU D 1 14  ? 119.244 105.271 181.671 1.00 63.05  ? 14  LEU D N   1 
ATOM   8269  C CA  . LEU D 1 14  ? 119.802 106.050 180.569 1.00 63.05  ? 14  LEU D CA  1 
ATOM   8270  C C   . LEU D 1 14  ? 120.256 107.422 181.046 1.00 63.05  ? 14  LEU D C   1 
ATOM   8271  O O   . LEU D 1 14  ? 121.311 107.917 180.631 1.00 63.05  ? 14  LEU D O   1 
ATOM   8272  C CB  . LEU D 1 14  ? 118.774 106.187 179.448 1.00 63.05  ? 14  LEU D CB  1 
ATOM   8273  C CG  . LEU D 1 14  ? 118.981 105.292 178.228 1.00 63.05  ? 14  LEU D CG  1 
ATOM   8274  C CD1 . LEU D 1 14  ? 118.891 103.829 178.621 1.00 63.05  ? 14  LEU D CD1 1 
ATOM   8275  C CD2 . LEU D 1 14  ? 117.968 105.623 177.149 1.00 63.05  ? 14  LEU D CD2 1 
ATOM   8276  N N   . ASP D 1 15  ? 119.464 108.056 181.913 1.00 65.63  ? 15  ASP D N   1 
ATOM   8277  C CA  . ASP D 1 15  ? 119.855 109.353 182.456 1.00 65.63  ? 15  ASP D CA  1 
ATOM   8278  C C   . ASP D 1 15  ? 121.126 109.244 183.290 1.00 65.63  ? 15  ASP D C   1 
ATOM   8279  O O   . ASP D 1 15  ? 121.996 110.120 183.227 1.00 65.63  ? 15  ASP D O   1 
ATOM   8280  C CB  . ASP D 1 15  ? 118.713 109.942 183.282 1.00 65.63  ? 15  ASP D CB  1 
ATOM   8281  C CG  . ASP D 1 15  ? 117.606 110.512 182.418 1.00 65.63  ? 15  ASP D CG  1 
ATOM   8282  O OD1 . ASP D 1 15  ? 117.649 110.311 181.186 1.00 65.63  ? 15  ASP D OD1 1 
ATOM   8283  O OD2 . ASP D 1 15  ? 116.694 111.164 182.970 1.00 65.63  ? 15  ASP D OD2 1 
ATOM   8284  N N   . LYS D 1 16  ? 121.249 108.180 184.085 1.00 62.58  ? 16  LYS D N   1 
ATOM   8285  C CA  . LYS D 1 16  ? 122.453 107.987 184.884 1.00 62.58  ? 16  LYS D CA  1 
ATOM   8286  C C   . LYS D 1 16  ? 123.657 107.657 184.012 1.00 62.58  ? 16  LYS D C   1 
ATOM   8287  O O   . LYS D 1 16  ? 124.799 107.911 184.410 1.00 62.58  ? 16  LYS D O   1 
ATOM   8288  C CB  . LYS D 1 16  ? 122.225 106.881 185.914 1.00 62.58  ? 16  LYS D CB  1 
ATOM   8289  C CG  . LYS D 1 16  ? 123.308 106.771 186.973 1.00 62.58  ? 16  LYS D CG  1 
ATOM   8290  C CD  . LYS D 1 16  ? 124.254 105.618 186.679 1.00 62.58  ? 16  LYS D CD  1 
ATOM   8291  C CE  . LYS D 1 16  ? 123.509 104.298 186.583 1.00 62.58  ? 16  LYS D CE  1 
ATOM   8292  N NZ  . LYS D 1 16  ? 124.428 103.162 186.295 1.00 62.58  ? 16  LYS D NZ  1 
ATOM   8293  N N   . LEU D 1 17  ? 123.425 107.087 182.830 1.00 61.24  ? 17  LEU D N   1 
ATOM   8294  C CA  . LEU D 1 17  ? 124.534 106.722 181.956 1.00 61.24  ? 17  LEU D CA  1 
ATOM   8295  C C   . LEU D 1 17  ? 125.040 107.920 181.161 1.00 61.24  ? 17  LEU D C   1 
ATOM   8296  O O   . LEU D 1 17  ? 126.240 108.213 181.166 1.00 61.24  ? 17  LEU D O   1 
ATOM   8297  C CB  . LEU D 1 17  ? 124.111 105.596 181.014 1.00 61.24  ? 17  LEU D CB  1 
ATOM   8298  C CG  . LEU D 1 17  ? 125.224 105.011 180.149 1.00 61.24  ? 17  LEU D CG  1 
ATOM   8299  C CD1 . LEU D 1 17  ? 126.352 104.498 181.024 1.00 61.24  ? 17  LEU D CD1 1 
ATOM   8300  C CD2 . LEU D 1 17  ? 124.681 103.904 179.266 1.00 61.24  ? 17  LEU D CD2 1 
ATOM   8301  N N   . MET D 1 18  ? 124.140 108.626 180.471 1.00 61.54  ? 18  MET D N   1 
ATOM   8302  C CA  . MET D 1 18  ? 124.560 109.746 179.637 1.00 61.54  ? 18  MET D CA  1 
ATOM   8303  C C   . MET D 1 18  ? 123.642 110.959 179.744 1.00 61.54  ? 18  MET D C   1 
ATOM   8304  O O   . MET D 1 18  ? 123.857 111.941 179.022 1.00 61.54  ? 18  MET D O   1 
ATOM   8305  C CB  . MET D 1 18  ? 124.664 109.309 178.171 1.00 61.54  ? 18  MET D CB  1 
ATOM   8306  C CG  . MET D 1 18  ? 123.337 109.281 177.430 1.00 61.54  ? 18  MET D CG  1 
ATOM   8307  S SD  . MET D 1 18  ? 123.344 108.136 176.042 1.00 61.54  ? 18  MET D SD  1 
ATOM   8308  C CE  . MET D 1 18  ? 123.458 106.571 176.900 1.00 61.54  ? 18  MET D CE  1 
ATOM   8309  N N   . GLY D 1 19  ? 122.650 110.941 180.624 1.00 65.69  ? 19  GLY D N   1 
ATOM   8310  C CA  . GLY D 1 19  ? 121.691 112.018 180.735 1.00 65.69  ? 19  GLY D CA  1 
ATOM   8311  C C   . GLY D 1 19  ? 122.173 113.149 181.617 1.00 65.69  ? 19  GLY D C   1 
ATOM   8312  O O   . GLY D 1 19  ? 123.371 113.328 181.852 1.00 65.69  ? 19  GLY D O   1 
ATOM   8313  N N   . ARG D 1 20  ? 121.209 113.931 182.110 1.00 68.16  ? 20  ARG D N   1 
ATOM   8314  C CA  . ARG D 1 20  ? 121.536 115.101 182.920 1.00 68.16  ? 20  ARG D CA  1 
ATOM   8315  C C   . ARG D 1 20  ? 122.218 114.706 184.223 1.00 68.16  ? 20  ARG D C   1 
ATOM   8316  O O   . ARG D 1 20  ? 123.192 115.343 184.639 1.00 68.16  ? 20  ARG D O   1 
ATOM   8317  C CB  . ARG D 1 20  ? 120.272 115.910 183.202 1.00 68.16  ? 20  ARG D CB  1 
ATOM   8318  N N   . THR D 1 21  ? 121.723 113.659 184.882 1.00 68.62  ? 21  THR D N   1 
ATOM   8319  C CA  . THR D 1 21  ? 122.296 113.227 186.150 1.00 68.62  ? 21  THR D CA  1 
ATOM   8320  C C   . THR D 1 21  ? 123.567 112.407 185.980 1.00 68.62  ? 21  THR D C   1 
ATOM   8321  O O   . THR D 1 21  ? 124.209 112.076 186.983 1.00 68.62  ? 21  THR D O   1 
ATOM   8322  C CB  . THR D 1 21  ? 121.274 112.411 186.944 1.00 68.62  ? 21  THR D CB  1 
ATOM   8323  O OG1 . THR D 1 21  ? 121.907 111.842 188.097 1.00 68.62  ? 21  THR D OG1 1 
ATOM   8324  C CG2 . THR D 1 21  ? 120.706 111.295 186.087 1.00 68.62  ? 21  THR D CG2 1 
ATOM   8325  N N   . SER D 1 22  ? 123.938 112.066 184.745 1.00 64.21  ? 22  SER D N   1 
ATOM   8326  C CA  . SER D 1 22  ? 125.120 111.241 184.527 1.00 64.21  ? 22  SER D CA  1 
ATOM   8327  C C   . SER D 1 22  ? 126.398 111.990 184.873 1.00 64.21  ? 22  SER D C   1 
ATOM   8328  O O   . SER D 1 22  ? 127.301 111.429 185.505 1.00 64.21  ? 22  SER D O   1 
ATOM   8329  C CB  . SER D 1 22  ? 125.165 110.771 183.075 1.00 64.21  ? 22  SER D CB  1 
ATOM   8330  O OG  . SER D 1 22  ? 125.257 111.874 182.191 1.00 64.21  ? 22  SER D OG  1 
ATOM   8331  N N   . GLY D 1 23  ? 126.496 113.253 184.466 1.00 64.76  ? 23  GLY D N   1 
ATOM   8332  C CA  . GLY D 1 23  ? 127.738 113.984 184.545 1.00 64.76  ? 23  GLY D CA  1 
ATOM   8333  C C   . GLY D 1 23  ? 128.675 113.745 183.385 1.00 64.76  ? 23  GLY D C   1 
ATOM   8334  O O   . GLY D 1 23  ? 129.721 114.402 183.308 1.00 64.76  ? 23  GLY D O   1 
ATOM   8335  N N   . TYR D 1 24  ? 128.338 112.828 182.483 1.00 58.10  ? 24  TYR D N   1 
ATOM   8336  C CA  . TYR D 1 24  ? 129.142 112.597 181.294 1.00 58.10  ? 24  TYR D CA  1 
ATOM   8337  C C   . TYR D 1 24  ? 128.994 113.760 180.324 1.00 58.10  ? 24  TYR D C   1 
ATOM   8338  O O   . TYR D 1 24  ? 127.890 114.261 180.094 1.00 58.10  ? 24  TYR D O   1 
ATOM   8339  C CB  . TYR D 1 24  ? 128.721 111.288 180.627 1.00 58.10  ? 24  TYR D CB  1 
ATOM   8340  C CG  . TYR D 1 24  ? 129.135 111.147 179.179 1.00 58.10  ? 24  TYR D CG  1 
ATOM   8341  C CD1 . TYR D 1 24  ? 130.420 110.752 178.839 1.00 58.10  ? 24  TYR D CD1 1 
ATOM   8342  C CD2 . TYR D 1 24  ? 128.233 111.389 178.153 1.00 58.10  ? 24  TYR D CD2 1 
ATOM   8343  C CE1 . TYR D 1 24  ? 130.797 110.615 177.521 1.00 58.10  ? 24  TYR D CE1 1 
ATOM   8344  C CE2 . TYR D 1 24  ? 128.604 111.255 176.833 1.00 58.10  ? 24  TYR D CE2 1 
ATOM   8345  C CZ  . TYR D 1 24  ? 129.887 110.868 176.523 1.00 58.10  ? 24  TYR D CZ  1 
ATOM   8346  O OH  . TYR D 1 24  ? 130.263 110.732 175.209 1.00 58.10  ? 24  TYR D OH  1 
ATOM   8347  N N   . ASP D 1 25  ? 130.113 114.189 179.753 1.00 59.61  ? 25  ASP D N   1 
ATOM   8348  C CA  . ASP D 1 25  ? 130.134 115.281 178.792 1.00 59.61  ? 25  ASP D CA  1 
ATOM   8349  C C   . ASP D 1 25  ? 130.412 114.725 177.404 1.00 59.61  ? 25  ASP D C   1 
ATOM   8350  O O   . ASP D 1 25  ? 131.274 113.856 177.239 1.00 59.61  ? 25  ASP D O   1 
ATOM   8351  C CB  . ASP D 1 25  ? 131.185 116.327 179.164 1.00 59.61  ? 25  ASP D CB  1 
ATOM   8352  C CG  . ASP D 1 25  ? 130.972 117.642 178.444 1.00 59.61  ? 25  ASP D CG  1 
ATOM   8353  O OD1 . ASP D 1 25  ? 130.936 117.640 177.196 1.00 59.61  ? 25  ASP D OD1 1 
ATOM   8354  O OD2 . ASP D 1 25  ? 130.828 118.678 179.125 1.00 59.61  ? 25  ASP D OD2 1 
ATOM   8355  N N   . ALA D 1 26  ? 129.682 115.227 176.414 1.00 54.27  ? 26  ALA D N   1 
ATOM   8356  C CA  . ALA D 1 26  ? 129.797 114.751 175.044 1.00 54.27  ? 26  ALA D CA  1 
ATOM   8357  C C   . ALA D 1 26  ? 130.839 115.507 174.236 1.00 54.27  ? 26  ALA D C   1 
ATOM   8358  O O   . ALA D 1 26  ? 130.973 115.252 173.036 1.00 54.27  ? 26  ALA D O   1 
ATOM   8359  C CB  . ALA D 1 26  ? 128.440 114.842 174.341 1.00 54.27  ? 26  ALA D CB  1 
ATOM   8360  N N   . ARG D 1 27  ? 131.573 116.428 174.854 1.00 54.03  ? 27  ARG D N   1 
ATOM   8361  C CA  . ARG D 1 27  ? 132.512 117.260 174.118 1.00 54.03  ? 27  ARG D CA  1 
ATOM   8362  C C   . ARG D 1 27  ? 133.968 116.872 174.332 1.00 54.03  ? 27  ARG D C   1 
ATOM   8363  O O   . ARG D 1 27  ? 134.814 117.241 173.511 1.00 54.03  ? 27  ARG D O   1 
ATOM   8364  C CB  . ARG D 1 27  ? 132.316 118.730 174.500 1.00 54.03  ? 27  ARG D CB  1 
ATOM   8365  C CG  . ARG D 1 27  ? 131.210 119.417 173.717 1.00 54.03  ? 27  ARG D CG  1 
ATOM   8366  C CD  . ARG D 1 27  ? 130.785 120.733 174.352 1.00 54.03  ? 27  ARG D CD  1 
ATOM   8367  N NE  . ARG D 1 27  ? 130.683 120.652 175.804 1.00 54.03  ? 27  ARG D NE  1 
ATOM   8368  C CZ  . ARG D 1 27  ? 131.561 121.178 176.647 1.00 54.03  ? 27  ARG D CZ  1 
ATOM   8369  N NH1 . ARG D 1 27  ? 132.625 121.835 176.215 1.00 54.03  ? 27  ARG D NH1 1 
ATOM   8370  N NH2 . ARG D 1 27  ? 131.368 121.041 177.955 1.00 54.03  ? 27  ARG D NH2 1 
ATOM   8371  N N   . ILE D 1 28  ? 134.280 116.138 175.394 1.00 51.33  ? 28  ILE D N   1 
ATOM   8372  C CA  . ILE D 1 28  ? 135.643 115.711 175.683 1.00 51.33  ? 28  ILE D CA  1 
ATOM   8373  C C   . ILE D 1 28  ? 135.817 114.284 175.188 1.00 51.33  ? 28  ILE D C   1 
ATOM   8374  O O   . ILE D 1 28  ? 135.045 113.392 175.560 1.00 51.33  ? 28  ILE D O   1 
ATOM   8375  C CB  . ILE D 1 28  ? 135.953 115.810 177.185 1.00 51.33  ? 28  ILE D CB  1 
ATOM   8376  C CG1 . ILE D 1 28  ? 135.660 117.218 177.696 1.00 51.33  ? 28  ILE D CG1 1 
ATOM   8377  C CG2 . ILE D 1 28  ? 137.399 115.445 177.450 1.00 51.33  ? 28  ILE D CG2 1 
ATOM   8378  C CD1 . ILE D 1 28  ? 135.753 117.343 179.197 1.00 51.33  ? 28  ILE D CD1 1 
ATOM   8379  N N   . ARG D 1 29  ? 136.829 114.067 174.355 1.00 52.59  ? 29  ARG D N   1 
ATOM   8380  C CA  . ARG D 1 29  ? 137.052 112.750 173.784 1.00 52.59  ? 29  ARG D CA  1 
ATOM   8381  C C   . ARG D 1 29  ? 137.458 111.757 174.873 1.00 52.59  ? 29  ARG D C   1 
ATOM   8382  O O   . ARG D 1 29  ? 138.019 112.144 175.901 1.00 52.59  ? 29  ARG D O   1 
ATOM   8383  C CB  . ARG D 1 29  ? 138.130 112.813 172.706 1.00 52.59  ? 29  ARG D CB  1 
ATOM   8384  C CG  . ARG D 1 29  ? 139.533 113.032 173.240 1.00 52.59  ? 29  ARG D CG  1 
ATOM   8385  C CD  . ARG D 1 29  ? 140.574 112.762 172.171 1.00 52.59  ? 29  ARG D CD  1 
ATOM   8386  N NE  . ARG D 1 29  ? 141.924 112.758 172.717 1.00 52.59  ? 29  ARG D NE  1 
ATOM   8387  C CZ  . ARG D 1 29  ? 142.500 111.705 173.280 1.00 52.59  ? 29  ARG D CZ  1 
ATOM   8388  N NH1 . ARG D 1 29  ? 141.868 110.549 173.388 1.00 52.59  ? 29  ARG D NH1 1 
ATOM   8389  N NH2 . ARG D 1 29  ? 143.740 111.815 173.745 1.00 52.59  ? 29  ARG D NH2 1 
ATOM   8390  N N   . PRO D 1 30  ? 137.167 110.472 174.680 1.00 51.92  ? 30  PRO D N   1 
ATOM   8391  C CA  . PRO D 1 30  ? 137.582 109.472 175.666 1.00 51.92  ? 30  PRO D CA  1 
ATOM   8392  C C   . PRO D 1 30  ? 139.096 109.387 175.757 1.00 51.92  ? 30  PRO D C   1 
ATOM   8393  O O   . PRO D 1 30  ? 139.812 109.664 174.793 1.00 51.92  ? 30  PRO D O   1 
ATOM   8394  C CB  . PRO D 1 30  ? 136.979 108.170 175.127 1.00 51.92  ? 30  PRO D CB  1 
ATOM   8395  C CG  . PRO D 1 30  ? 136.793 108.417 173.675 1.00 51.92  ? 30  PRO D CG  1 
ATOM   8396  C CD  . PRO D 1 30  ? 136.436 109.865 173.558 1.00 51.92  ? 30  PRO D CD  1 
ATOM   8397  N N   . ASN D 1 31  ? 139.576 109.005 176.940 1.00 54.97  ? 31  ASN D N   1 
ATOM   8398  C CA  . ASN D 1 31  ? 141.008 108.912 177.220 1.00 54.97  ? 31  ASN D CA  1 
ATOM   8399  C C   . ASN D 1 31  ? 141.699 110.250 176.965 1.00 54.97  ? 31  ASN D C   1 
ATOM   8400  O O   . ASN D 1 31  ? 142.725 110.328 176.286 1.00 54.97  ? 31  ASN D O   1 
ATOM   8401  C CB  . ASN D 1 31  ? 141.659 107.792 176.405 1.00 54.97  ? 31  ASN D CB  1 
ATOM   8402  C CG  . ASN D 1 31  ? 141.043 106.437 176.682 1.00 54.97  ? 31  ASN D CG  1 
ATOM   8403  O OD1 . ASN D 1 31  ? 140.675 106.129 177.815 1.00 54.97  ? 31  ASN D OD1 1 
ATOM   8404  N ND2 . ASN D 1 31  ? 140.927 105.617 175.644 1.00 54.97  ? 31  ASN D ND2 1 
ATOM   8405  N N   . PHE D 1 32  ? 141.116 111.314 177.510 1.00 59.74  ? 32  PHE D N   1 
ATOM   8406  C CA  . PHE D 1 32  ? 141.688 112.642 177.347 1.00 59.74  ? 32  PHE D CA  1 
ATOM   8407  C C   . PHE D 1 32  ? 143.048 112.720 178.025 1.00 59.74  ? 32  PHE D C   1 
ATOM   8408  O O   . PHE D 1 32  ? 143.266 112.126 179.085 1.00 59.74  ? 32  PHE D O   1 
ATOM   8409  C CB  . PHE D 1 32  ? 140.748 113.698 177.926 1.00 59.74  ? 32  PHE D CB  1 
ATOM   8410  C CG  . PHE D 1 32  ? 141.107 115.102 177.543 1.00 59.74  ? 32  PHE D CG  1 
ATOM   8411  C CD1 . PHE D 1 32  ? 140.804 115.588 176.285 1.00 59.74  ? 32  PHE D CD1 1 
ATOM   8412  C CD2 . PHE D 1 32  ? 141.745 115.937 178.441 1.00 59.74  ? 32  PHE D CD2 1 
ATOM   8413  C CE1 . PHE D 1 32  ? 141.130 116.880 175.929 1.00 59.74  ? 32  PHE D CE1 1 
ATOM   8414  C CE2 . PHE D 1 32  ? 142.075 117.230 178.091 1.00 59.74  ? 32  PHE D CE2 1 
ATOM   8415  C CZ  . PHE D 1 32  ? 141.766 117.702 176.833 1.00 59.74  ? 32  PHE D CZ  1 
ATOM   8416  N N   . LYS D 1 33  ? 143.967 113.459 177.400 1.00 62.89  ? 33  LYS D N   1 
ATOM   8417  C CA  . LYS D 1 33  ? 145.343 113.592 177.884 1.00 62.89  ? 33  LYS D CA  1 
ATOM   8418  C C   . LYS D 1 33  ? 146.000 112.226 178.062 1.00 62.89  ? 33  LYS D C   1 
ATOM   8419  O O   . LYS D 1 33  ? 146.739 111.990 179.020 1.00 62.89  ? 33  LYS D O   1 
ATOM   8420  C CB  . LYS D 1 33  ? 145.400 114.395 179.186 1.00 62.89  ? 33  LYS D CB  1 
ATOM   8421  C CG  . LYS D 1 33  ? 145.340 115.898 178.990 1.00 62.89  ? 33  LYS D CG  1 
ATOM   8422  C CD  . LYS D 1 33  ? 146.500 116.387 178.143 1.00 62.89  ? 33  LYS D CD  1 
ATOM   8423  C CE  . LYS D 1 33  ? 146.459 117.896 177.978 1.00 62.89  ? 33  LYS D CE  1 
ATOM   8424  N NZ  . LYS D 1 33  ? 147.479 118.377 177.006 1.00 62.89  ? 33  LYS D NZ  1 
ATOM   8425  N N   . GLY D 1 34  ? 145.726 111.317 177.132 1.00 59.49  ? 34  GLY D N   1 
ATOM   8426  C CA  . GLY D 1 34  ? 146.272 109.984 177.185 1.00 59.49  ? 34  GLY D CA  1 
ATOM   8427  C C   . GLY D 1 34  ? 146.542 109.428 175.803 1.00 59.49  ? 34  GLY D C   1 
ATOM   8428  O O   . GLY D 1 34  ? 146.817 110.168 174.854 1.00 59.49  ? 34  GLY D O   1 
ATOM   8429  N N   . PRO D 1 35  ? 146.473 108.103 175.666 1.00 50.70  ? 35  PRO D N   1 
ATOM   8430  C CA  . PRO D 1 35  ? 146.711 107.497 174.361 1.00 50.70  ? 35  PRO D CA  1 
ATOM   8431  C C   . PRO D 1 35  ? 145.640 107.916 173.372 1.00 50.70  ? 35  PRO D C   1 
ATOM   8432  O O   . PRO D 1 35  ? 144.483 108.160 173.753 1.00 50.70  ? 35  PRO D O   1 
ATOM   8433  C CB  . PRO D 1 35  ? 146.644 105.987 174.654 1.00 50.70  ? 35  PRO D CB  1 
ATOM   8434  C CG  . PRO D 1 35  ? 145.841 105.880 175.901 1.00 50.70  ? 35  PRO D CG  1 
ATOM   8435  C CD  . PRO D 1 35  ? 146.164 107.103 176.701 1.00 50.70  ? 35  PRO D CD  1 
ATOM   8436  N N   . PRO D 1 36  ? 145.980 108.025 172.088 1.00 45.32  ? 36  PRO D N   1 
ATOM   8437  C CA  . PRO D 1 36  ? 144.962 108.369 171.089 1.00 45.32  ? 36  PRO D CA  1 
ATOM   8438  C C   . PRO D 1 36  ? 143.984 107.220 170.904 1.00 45.32  ? 36  PRO D C   1 
ATOM   8439  O O   . PRO D 1 36  ? 144.385 106.067 170.736 1.00 45.32  ? 36  PRO D O   1 
ATOM   8440  C CB  . PRO D 1 36  ? 145.782 108.622 169.820 1.00 45.32  ? 36  PRO D CB  1 
ATOM   8441  C CG  . PRO D 1 36  ? 147.018 107.817 170.011 1.00 45.32  ? 36  PRO D CG  1 
ATOM   8442  C CD  . PRO D 1 36  ? 147.310 107.840 171.485 1.00 45.32  ? 36  PRO D CD  1 
ATOM   8443  N N   . VAL D 1 37  ? 142.692 107.545 170.934 1.00 41.95  ? 37  VAL D N   1 
ATOM   8444  C CA  . VAL D 1 37  ? 141.666 106.523 170.785 1.00 41.95  ? 37  VAL D CA  1 
ATOM   8445  C C   . VAL D 1 37  ? 141.641 106.040 169.341 1.00 41.95  ? 37  VAL D C   1 
ATOM   8446  O O   . VAL D 1 37  ? 141.706 106.837 168.396 1.00 41.95  ? 37  VAL D O   1 
ATOM   8447  C CB  . VAL D 1 37  ? 140.300 107.052 171.252 1.00 41.95  ? 37  VAL D CB  1 
ATOM   8448  C CG1 . VAL D 1 37  ? 139.624 107.902 170.191 1.00 41.95  ? 37  VAL D CG1 1 
ATOM   8449  C CG2 . VAL D 1 37  ? 139.403 105.896 171.651 1.00 41.95  ? 37  VAL D CG2 1 
ATOM   8450  N N   . ASN D 1 38  ? 141.624 104.724 169.164 1.00 39.89  ? 38  ASN D N   1 
ATOM   8451  C CA  . ASN D 1 38  ? 141.605 104.135 167.835 1.00 39.89  ? 38  ASN D CA  1 
ATOM   8452  C C   . ASN D 1 38  ? 140.178 103.780 167.441 1.00 39.89  ? 38  ASN D C   1 
ATOM   8453  O O   . ASN D 1 38  ? 139.378 103.350 168.275 1.00 39.89  ? 38  ASN D O   1 
ATOM   8454  C CB  . ASN D 1 38  ? 142.509 102.900 167.774 1.00 39.89  ? 38  ASN D CB  1 
ATOM   8455  C CG  . ASN D 1 38  ? 142.077 101.796 168.725 1.00 39.89  ? 38  ASN D CG  1 
ATOM   8456  O OD1 . ASN D 1 38  ? 141.035 101.172 168.528 1.00 39.89  ? 38  ASN D OD1 1 
ATOM   8457  N ND2 . ASN D 1 38  ? 142.881 101.538 169.760 1.00 39.89  ? 38  ASN D ND2 1 
ATOM   8458  N N   . VAL D 1 39  ? 139.862 103.980 166.166 1.00 32.09  ? 39  VAL D N   1 
ATOM   8459  C CA  . VAL D 1 39  ? 138.532 103.728 165.628 1.00 32.09  ? 39  VAL D CA  1 
ATOM   8460  C C   . VAL D 1 39  ? 138.658 102.732 164.487 1.00 32.09  ? 39  VAL D C   1 
ATOM   8461  O O   . VAL D 1 39  ? 139.407 102.968 163.533 1.00 32.09  ? 39  VAL D O   1 
ATOM   8462  C CB  . VAL D 1 39  ? 137.864 105.025 165.143 1.00 32.09  ? 39  VAL D CB  1 
ATOM   8463  C CG1 . VAL D 1 39  ? 136.646 104.708 164.305 1.00 32.09  ? 39  VAL D CG1 1 
ATOM   8464  C CG2 . VAL D 1 39  ? 137.493 105.896 166.321 1.00 32.09  ? 39  VAL D CG2 1 
ATOM   8465  N N   . THR D 1 40  ? 137.925 101.628 164.582 1.00 32.12  ? 40  THR D N   1 
ATOM   8466  C CA  . THR D 1 40  ? 137.899 100.614 163.537 1.00 32.12  ? 40  THR D CA  1 
ATOM   8467  C C   . THR D 1 40  ? 136.591 100.747 162.771 1.00 32.12  ? 40  THR D C   1 
ATOM   8468  O O   . THR D 1 40  ? 135.513 100.594 163.352 1.00 32.12  ? 40  THR D O   1 
ATOM   8469  C CB  . THR D 1 40  ? 138.032 99.211  164.126 1.00 32.12  ? 40  THR D CB  1 
ATOM   8470  O OG1 . THR D 1 40  ? 136.741 98.739  164.526 1.00 32.12  ? 40  THR D OG1 1 
ATOM   8471  C CG2 . THR D 1 40  ? 138.950 99.227  165.335 1.00 32.12  ? 40  THR D CG2 1 
ATOM   8472  N N   . CYS D 1 41  ? 136.685 101.024 161.474 1.00 31.63  ? 41  CYS D N   1 
ATOM   8473  C CA  . CYS D 1 41  ? 135.518 101.282 160.645 1.00 31.63  ? 41  CYS D CA  1 
ATOM   8474  C C   . CYS D 1 41  ? 135.452 100.282 159.502 1.00 31.63  ? 41  CYS D C   1 
ATOM   8475  O O   . CYS D 1 41  ? 136.484 99.849  158.984 1.00 31.63  ? 41  CYS D O   1 
ATOM   8476  C CB  . CYS D 1 41  ? 135.542 102.707 160.087 1.00 31.63  ? 41  CYS D CB  1 
ATOM   8477  S SG  . CYS D 1 41  ? 137.088 103.180 159.300 1.00 31.63  ? 41  CYS D SG  1 
ATOM   8478  N N   . ASN D 1 42  ? 134.232 99.909  159.122 1.00 31.80  ? 42  ASN D N   1 
ATOM   8479  C CA  . ASN D 1 42  ? 133.994 99.071  157.957 1.00 31.80  ? 42  ASN D CA  1 
ATOM   8480  C C   . ASN D 1 42  ? 132.791 99.616  157.204 1.00 31.80  ? 42  ASN D C   1 
ATOM   8481  O O   . ASN D 1 42  ? 131.906 100.239 157.792 1.00 31.80  ? 42  ASN D O   1 
ATOM   8482  C CB  . ASN D 1 42  ? 133.759 97.608  158.340 1.00 31.80  ? 42  ASN D CB  1 
ATOM   8483  C CG  . ASN D 1 42  ? 132.537 97.422  159.205 1.00 31.80  ? 42  ASN D CG  1 
ATOM   8484  O OD1 . ASN D 1 42  ? 132.125 98.334  159.919 1.00 31.80  ? 42  ASN D OD1 1 
ATOM   8485  N ND2 . ASN D 1 42  ? 131.950 96.234  159.152 1.00 31.80  ? 42  ASN D ND2 1 
ATOM   8486  N N   . ILE D 1 43  ? 132.762 99.371  155.899 1.00 29.44  ? 43  ILE D N   1 
ATOM   8487  C CA  . ILE D 1 43  ? 131.796 99.992  155.002 1.00 29.44  ? 43  ILE D CA  1 
ATOM   8488  C C   . ILE D 1 43  ? 131.009 98.905  154.289 1.00 29.44  ? 43  ILE D C   1 
ATOM   8489  O O   . ILE D 1 43  ? 131.595 97.988  153.706 1.00 29.44  ? 43  ILE D O   1 
ATOM   8490  C CB  . ILE D 1 43  ? 132.490 100.912 153.985 1.00 29.44  ? 43  ILE D CB  1 
ATOM   8491  C CG1 . ILE D 1 43  ? 133.133 102.097 154.701 1.00 29.44  ? 43  ILE D CG1 1 
ATOM   8492  C CG2 . ILE D 1 43  ? 131.505 101.392 152.942 1.00 29.44  ? 43  ILE D CG2 1 
ATOM   8493  C CD1 . ILE D 1 43  ? 133.954 102.975 153.798 1.00 29.44  ? 43  ILE D CD1 1 
ATOM   8494  N N   . PHE D 1 44  ? 129.686 99.013  154.334 1.00 33.11  ? 44  PHE D N   1 
ATOM   8495  C CA  . PHE D 1 44  ? 128.791 98.165  153.561 1.00 33.11  ? 44  PHE D CA  1 
ATOM   8496  C C   . PHE D 1 44  ? 128.206 98.996  152.431 1.00 33.11  ? 44  PHE D C   1 
ATOM   8497  O O   . PHE D 1 44  ? 127.678 100.085 152.670 1.00 33.11  ? 44  PHE D O   1 
ATOM   8498  C CB  . PHE D 1 44  ? 127.674 97.597  154.440 1.00 33.11  ? 44  PHE D CB  1 
ATOM   8499  C CG  . PHE D 1 44  ? 126.711 96.703  153.708 1.00 33.11  ? 44  PHE D CG  1 
ATOM   8500  C CD1 . PHE D 1 44  ? 125.677 97.234  152.957 1.00 33.11  ? 44  PHE D CD1 1 
ATOM   8501  C CD2 . PHE D 1 44  ? 126.830 95.330  153.788 1.00 33.11  ? 44  PHE D CD2 1 
ATOM   8502  C CE1 . PHE D 1 44  ? 124.793 96.415  152.292 1.00 33.11  ? 44  PHE D CE1 1 
ATOM   8503  C CE2 . PHE D 1 44  ? 125.944 94.506  153.125 1.00 33.11  ? 44  PHE D CE2 1 
ATOM   8504  C CZ  . PHE D 1 44  ? 124.926 95.050  152.376 1.00 33.11  ? 44  PHE D CZ  1 
ATOM   8505  N N   . ILE D 1 45  ? 128.293 98.483  151.210 1.00 29.42  ? 45  ILE D N   1 
ATOM   8506  C CA  . ILE D 1 45  ? 127.799 99.181  150.030 1.00 29.42  ? 45  ILE D CA  1 
ATOM   8507  C C   . ILE D 1 45  ? 126.413 98.653  149.698 1.00 29.42  ? 45  ILE D C   1 
ATOM   8508  O O   . ILE D 1 45  ? 126.207 97.437  149.617 1.00 29.42  ? 45  ILE D O   1 
ATOM   8509  C CB  . ILE D 1 45  ? 128.752 99.004  148.838 1.00 29.42  ? 45  ILE D CB  1 
ATOM   8510  C CG1 . ILE D 1 45  ? 130.068 99.725  149.104 1.00 29.42  ? 45  ILE D CG1 1 
ATOM   8511  C CG2 . ILE D 1 45  ? 128.114 99.527  147.572 1.00 29.42  ? 45  ILE D CG2 1 
ATOM   8512  C CD1 . ILE D 1 45  ? 131.014 99.670  147.947 1.00 29.42  ? 45  ILE D CD1 1 
ATOM   8513  N N   . ASN D 1 46  ? 125.463 99.564  149.510 1.00 28.35  ? 46  ASN D N   1 
ATOM   8514  C CA  . ASN D 1 46  ? 124.103 99.198  149.140 1.00 28.35  ? 46  ASN D CA  1 
ATOM   8515  C C   . ASN D 1 46  ? 123.800 99.476  147.677 1.00 28.35  ? 46  ASN D C   1 
ATOM   8516  O O   . ASN D 1 46  ? 123.074 98.707  147.042 1.00 28.35  ? 46  ASN D O   1 
ATOM   8517  C CB  . ASN D 1 46  ? 123.097 99.945  150.017 1.00 28.35  ? 46  ASN D CB  1 
ATOM   8518  C CG  . ASN D 1 46  ? 121.789 99.203  150.162 1.00 28.35  ? 46  ASN D CG  1 
ATOM   8519  O OD1 . ASN D 1 46  ? 121.403 98.426  149.291 1.00 28.35  ? 46  ASN D OD1 1 
ATOM   8520  N ND2 . ASN D 1 46  ? 121.098 99.438  151.268 1.00 28.35  ? 46  ASN D ND2 1 
ATOM   8521  N N   . SER D 1 47  ? 124.342 100.557 147.127 1.00 30.11  ? 47  SER D N   1 
ATOM   8522  C CA  . SER D 1 47  ? 124.100 100.925 145.743 1.00 30.11  ? 47  SER D CA  1 
ATOM   8523  C C   . SER D 1 47  ? 125.395 101.427 145.129 1.00 30.11  ? 47  SER D C   1 
ATOM   8524  O O   . SER D 1 47  ? 126.351 101.764 145.830 1.00 30.11  ? 47  SER D O   1 
ATOM   8525  C CB  . SER D 1 47  ? 123.007 101.993 145.621 1.00 30.11  ? 47  SER D CB  1 
ATOM   8526  O OG  . SER D 1 47  ? 122.994 102.559 144.323 1.00 30.11  ? 47  SER D OG  1 
ATOM   8527  N N   . PHE D 1 48  ? 125.412 101.472 143.801 1.00 33.94  ? 48  PHE D N   1 
ATOM   8528  C CA  . PHE D 1 48  ? 126.597 101.861 143.055 1.00 33.94  ? 48  PHE D CA  1 
ATOM   8529  C C   . PHE D 1 48  ? 126.183 102.105 141.614 1.00 33.94  ? 48  PHE D C   1 
ATOM   8530  O O   . PHE D 1 48  ? 125.419 101.321 141.048 1.00 33.94  ? 48  PHE D O   1 
ATOM   8531  C CB  . PHE D 1 48  ? 127.673 100.772 143.128 1.00 33.94  ? 48  PHE D CB  1 
ATOM   8532  C CG  . PHE D 1 48  ? 129.074 101.290 143.040 1.00 33.94  ? 48  PHE D CG  1 
ATOM   8533  C CD1 . PHE D 1 48  ? 129.505 101.979 141.924 1.00 33.94  ? 48  PHE D CD1 1 
ATOM   8534  C CD2 . PHE D 1 48  ? 129.967 101.071 144.071 1.00 33.94  ? 48  PHE D CD2 1 
ATOM   8535  C CE1 . PHE D 1 48  ? 130.797 102.448 141.843 1.00 33.94  ? 48  PHE D CE1 1 
ATOM   8536  C CE2 . PHE D 1 48  ? 131.259 101.539 143.994 1.00 33.94  ? 48  PHE D CE2 1 
ATOM   8537  C CZ  . PHE D 1 48  ? 131.675 102.228 142.879 1.00 33.94  ? 48  PHE D CZ  1 
ATOM   8538  N N   . GLY D 1 49  ? 126.678 103.183 141.031 1.00 35.49  ? 49  GLY D N   1 
ATOM   8539  C CA  . GLY D 1 49  ? 126.390 103.468 139.643 1.00 35.49  ? 49  GLY D CA  1 
ATOM   8540  C C   . GLY D 1 49  ? 126.452 104.957 139.374 1.00 35.49  ? 49  GLY D C   1 
ATOM   8541  O O   . GLY D 1 49  ? 127.069 105.709 140.119 1.00 35.49  ? 49  GLY D O   1 
ATOM   8542  N N   . SER D 1 50  ? 125.793 105.349 138.282 1.00 41.33  ? 50  SER D N   1 
ATOM   8543  C CA  . SER D 1 50  ? 125.781 106.734 137.813 1.00 41.33  ? 50  SER D CA  1 
ATOM   8544  C C   . SER D 1 50  ? 127.199 107.255 137.602 1.00 41.33  ? 50  SER D C   1 
ATOM   8545  O O   . SER D 1 50  ? 127.505 108.413 137.891 1.00 41.33  ? 50  SER D O   1 
ATOM   8546  C CB  . SER D 1 50  ? 125.005 107.638 138.772 1.00 41.33  ? 50  SER D CB  1 
ATOM   8547  O OG  . SER D 1 50  ? 125.006 108.979 138.315 1.00 41.33  ? 50  SER D OG  1 
ATOM   8548  N N   . ILE D 1 51  ? 128.073 106.391 137.090 1.00 39.02  ? 51  ILE D N   1 
ATOM   8549  C CA  . ILE D 1 51  ? 129.462 106.752 136.819 1.00 39.02  ? 51  ILE D CA  1 
ATOM   8550  C C   . ILE D 1 51  ? 129.473 107.580 135.539 1.00 39.02  ? 51  ILE D C   1 
ATOM   8551  O O   . ILE D 1 51  ? 129.391 107.038 134.436 1.00 39.02  ? 51  ILE D O   1 
ATOM   8552  C CB  . ILE D 1 51  ? 130.359 105.519 136.701 1.00 39.02  ? 51  ILE D CB  1 
ATOM   8553  C CG1 . ILE D 1 51  ? 130.227 104.649 137.948 1.00 39.02  ? 51  ILE D CG1 1 
ATOM   8554  C CG2 . ILE D 1 51  ? 131.802 105.933 136.491 1.00 39.02  ? 51  ILE D CG2 1 
ATOM   8555  C CD1 . ILE D 1 51  ? 131.145 103.458 137.951 1.00 39.02  ? 51  ILE D CD1 1 
ATOM   8556  N N   . ALA D 1 52  ? 129.576 108.897 135.679 1.00 50.66  ? 52  ALA D N   1 
ATOM   8557  C CA  . ALA D 1 52  ? 129.571 109.807 134.543 1.00 50.66  ? 52  ALA D CA  1 
ATOM   8558  C C   . ALA D 1 52  ? 130.998 110.250 134.256 1.00 50.66  ? 52  ALA D C   1 
ATOM   8559  O O   . ALA D 1 52  ? 131.668 110.808 135.131 1.00 50.66  ? 52  ALA D O   1 
ATOM   8560  C CB  . ALA D 1 52  ? 128.675 111.015 134.814 1.00 50.66  ? 52  ALA D CB  1 
ATOM   8561  N N   . GLU D 1 53  ? 131.460 110.000 133.031 1.00 57.68  ? 53  GLU D N   1 
ATOM   8562  C CA  . GLU D 1 53  ? 132.810 110.392 132.652 1.00 57.68  ? 53  GLU D CA  1 
ATOM   8563  C C   . GLU D 1 53  ? 132.920 111.886 132.387 1.00 57.68  ? 53  GLU D C   1 
ATOM   8564  O O   . GLU D 1 53  ? 134.008 112.455 132.525 1.00 57.68  ? 53  GLU D O   1 
ATOM   8565  C CB  . GLU D 1 53  ? 133.256 109.606 131.419 1.00 57.68  ? 53  GLU D CB  1 
ATOM   8566  C CG  . GLU D 1 53  ? 133.444 108.122 131.672 1.00 57.68  ? 53  GLU D CG  1 
ATOM   8567  C CD  . GLU D 1 53  ? 132.573 107.264 130.777 1.00 57.68  ? 53  GLU D CD  1 
ATOM   8568  O OE1 . GLU D 1 53  ? 131.803 107.830 129.973 1.00 57.68  ? 53  GLU D OE1 1 
ATOM   8569  O OE2 . GLU D 1 53  ? 132.653 106.022 130.879 1.00 57.68  ? 53  GLU D OE2 1 
ATOM   8570  N N   . THR D 1 54  ? 131.816 112.531 132.003 1.00 60.64  ? 54  THR D N   1 
ATOM   8571  C CA  . THR D 1 54  ? 131.860 113.958 131.696 1.00 60.64  ? 54  THR D CA  1 
ATOM   8572  C C   . THR D 1 54  ? 132.241 114.777 132.922 1.00 60.64  ? 54  THR D C   1 
ATOM   8573  O O   . THR D 1 54  ? 133.042 115.715 132.827 1.00 60.64  ? 54  THR D O   1 
ATOM   8574  C CB  . THR D 1 54  ? 130.511 114.419 131.145 1.00 60.64  ? 54  THR D CB  1 
ATOM   8575  O OG1 . THR D 1 54  ? 129.494 114.208 132.132 1.00 60.64  ? 54  THR D OG1 1 
ATOM   8576  C CG2 . THR D 1 54  ? 130.157 113.639 129.889 1.00 60.64  ? 54  THR D CG2 1 
ATOM   8577  N N   . THR D 1 55  ? 131.679 114.441 134.080 1.00 52.51  ? 55  THR D N   1 
ATOM   8578  C CA  . THR D 1 55  ? 131.975 115.144 135.320 1.00 52.51  ? 55  THR D CA  1 
ATOM   8579  C C   . THR D 1 55  ? 132.918 114.375 136.236 1.00 52.51  ? 55  THR D C   1 
ATOM   8580  O O   . THR D 1 55  ? 133.340 114.923 137.259 1.00 52.51  ? 55  THR D O   1 
ATOM   8581  C CB  . THR D 1 55  ? 130.676 115.459 136.071 1.00 52.51  ? 55  THR D CB  1 
ATOM   8582  O OG1 . THR D 1 55  ? 130.254 114.303 136.801 1.00 52.51  ? 55  THR D OG1 1 
ATOM   8583  C CG2 . THR D 1 55  ? 129.582 115.857 135.095 1.00 52.51  ? 55  THR D CG2 1 
ATOM   8584  N N   . MET D 1 56  ? 133.251 113.128 135.897 1.00 49.92  ? 56  MET D N   1 
ATOM   8585  C CA  . MET D 1 56  ? 134.229 112.323 136.630 1.00 49.92  ? 56  MET D CA  1 
ATOM   8586  C C   . MET D 1 56  ? 133.828 112.144 138.096 1.00 49.92  ? 56  MET D C   1 
ATOM   8587  O O   . MET D 1 56  ? 134.534 112.555 139.018 1.00 49.92  ? 56  MET D O   1 
ATOM   8588  C CB  . MET D 1 56  ? 135.630 112.933 136.515 1.00 49.92  ? 56  MET D CB  1 
ATOM   8589  C CG  . MET D 1 56  ? 136.196 112.919 135.109 1.00 49.92  ? 56  MET D CG  1 
ATOM   8590  S SD  . MET D 1 56  ? 137.977 112.649 135.081 1.00 49.92  ? 56  MET D SD  1 
ATOM   8591  C CE  . MET D 1 56  ? 138.383 113.258 133.447 1.00 49.92  ? 56  MET D CE  1 
ATOM   8592  N N   . ASP D 1 57  ? 132.674 111.513 138.298 1.00 39.11  ? 57  ASP D N   1 
ATOM   8593  C CA  . ASP D 1 57  ? 132.219 111.197 139.645 1.00 39.11  ? 57  ASP D CA  1 
ATOM   8594  C C   . ASP D 1 57  ? 131.239 110.037 139.582 1.00 39.11  ? 57  ASP D C   1 
ATOM   8595  O O   . ASP D 1 57  ? 130.655 109.748 138.536 1.00 39.11  ? 57  ASP D O   1 
ATOM   8596  C CB  . ASP D 1 57  ? 131.573 112.408 140.324 1.00 39.11  ? 57  ASP D CB  1 
ATOM   8597  C CG  . ASP D 1 57  ? 130.519 113.067 139.464 1.00 39.11  ? 57  ASP D CG  1 
ATOM   8598  O OD1 . ASP D 1 57  ? 129.533 112.394 139.099 1.00 39.11  ? 57  ASP D OD1 1 
ATOM   8599  O OD2 . ASP D 1 57  ? 130.673 114.266 139.151 1.00 39.11  ? 57  ASP D OD2 1 
ATOM   8600  N N   . TYR D 1 58  ? 131.064 109.381 140.726 1.00 31.47  ? 58  TYR D N   1 
ATOM   8601  C CA  . TYR D 1 58  ? 130.147 108.261 140.858 1.00 31.47  ? 58  TYR D CA  1 
ATOM   8602  C C   . TYR D 1 58  ? 129.461 108.341 142.212 1.00 31.47  ? 58  TYR D C   1 
ATOM   8603  O O   . TYR D 1 58  ? 130.037 108.831 143.184 1.00 31.47  ? 58  TYR D O   1 
ATOM   8604  C CB  . TYR D 1 58  ? 130.872 106.921 140.709 1.00 31.47  ? 58  TYR D CB  1 
ATOM   8605  C CG  . TYR D 1 58  ? 131.870 106.641 141.803 1.00 31.47  ? 58  TYR D CG  1 
ATOM   8606  C CD1 . TYR D 1 58  ? 133.089 107.294 141.838 1.00 31.47  ? 58  TYR D CD1 1 
ATOM   8607  C CD2 . TYR D 1 58  ? 131.596 105.720 142.798 1.00 31.47  ? 58  TYR D CD2 1 
ATOM   8608  C CE1 . TYR D 1 58  ? 134.004 107.040 142.836 1.00 31.47  ? 58  TYR D CE1 1 
ATOM   8609  C CE2 . TYR D 1 58  ? 132.506 105.459 143.799 1.00 31.47  ? 58  TYR D CE2 1 
ATOM   8610  C CZ  . TYR D 1 58  ? 133.708 106.122 143.813 1.00 31.47  ? 58  TYR D CZ  1 
ATOM   8611  O OH  . TYR D 1 58  ? 134.618 105.866 144.810 1.00 31.47  ? 58  TYR D OH  1 
ATOM   8612  N N   . ARG D 1 59  ? 128.227 107.852 142.269 1.00 32.27  ? 59  ARG D N   1 
ATOM   8613  C CA  . ARG D 1 59  ? 127.406 107.933 143.469 1.00 32.27  ? 59  ARG D CA  1 
ATOM   8614  C C   . ARG D 1 59  ? 127.344 106.574 144.145 1.00 32.27  ? 59  ARG D C   1 
ATOM   8615  O O   . ARG D 1 59  ? 127.077 105.563 143.489 1.00 32.27  ? 59  ARG D O   1 
ATOM   8616  C CB  . ARG D 1 59  ? 125.992 108.411 143.137 1.00 32.27  ? 59  ARG D CB  1 
ATOM   8617  C CG  . ARG D 1 59  ? 125.933 109.805 142.551 1.00 32.27  ? 59  ARG D CG  1 
ATOM   8618  C CD  . ARG D 1 59  ? 124.805 110.614 143.166 1.00 32.27  ? 59  ARG D CD  1 
ATOM   8619  N NE  . ARG D 1 59  ? 123.514 110.330 142.554 1.00 32.27  ? 59  ARG D NE  1 
ATOM   8620  C CZ  . ARG D 1 59  ? 122.442 109.930 143.224 1.00 32.27  ? 59  ARG D CZ  1 
ATOM   8621  N NH1 . ARG D 1 59  ? 122.475 109.744 144.533 1.00 32.27  ? 59  ARG D NH1 1 
ATOM   8622  N NH2 . ARG D 1 59  ? 121.308 109.713 142.564 1.00 32.27  ? 59  ARG D NH2 1 
ATOM   8623  N N   . VAL D 1 60  ? 127.583 106.552 145.453 1.00 30.77  ? 60  VAL D N   1 
ATOM   8624  C CA  . VAL D 1 60  ? 127.467 105.340 146.249 1.00 30.77  ? 60  VAL D CA  1 
ATOM   8625  C C   . VAL D 1 60  ? 126.375 105.545 147.290 1.00 30.77  ? 60  VAL D C   1 
ATOM   8626  O O   . VAL D 1 60  ? 125.815 106.630 147.435 1.00 30.77  ? 60  VAL D O   1 
ATOM   8627  C CB  . VAL D 1 60  ? 128.794 104.945 146.920 1.00 30.77  ? 60  VAL D CB  1 
ATOM   8628  C CG1 . VAL D 1 60  ? 129.807 104.542 145.879 1.00 30.77  ? 60  VAL D CG1 1 
ATOM   8629  C CG2 . VAL D 1 60  ? 129.322 106.090 147.747 1.00 30.77  ? 60  VAL D CG2 1 
ATOM   8630  N N   . ASN D 1 61  ? 126.073 104.470 148.014 1.00 39.27  ? 61  ASN D N   1 
ATOM   8631  C CA  . ASN D 1 61  ? 125.077 104.503 149.082 1.00 39.27  ? 61  ASN D CA  1 
ATOM   8632  C C   . ASN D 1 61  ? 125.544 103.500 150.131 1.00 39.27  ? 61  ASN D C   1 
ATOM   8633  O O   . ASN D 1 61  ? 125.251 102.308 150.020 1.00 39.27  ? 61  ASN D O   1 
ATOM   8634  C CB  . ASN D 1 61  ? 123.695 104.162 148.545 1.00 39.27  ? 61  ASN D CB  1 
ATOM   8635  C CG  . ASN D 1 61  ? 122.581 104.627 149.452 1.00 39.27  ? 61  ASN D CG  1 
ATOM   8636  O OD1 . ASN D 1 61  ? 122.085 103.868 150.283 1.00 39.27  ? 61  ASN D OD1 1 
ATOM   8637  N ND2 . ASN D 1 61  ? 122.173 105.878 149.293 1.00 39.27  ? 61  ASN D ND2 1 
ATOM   8638  N N   . ILE D 1 62  ? 126.254 103.984 151.142 1.00 47.29  ? 62  ILE D N   1 
ATOM   8639  C CA  . ILE D 1 62  ? 127.019 103.115 152.025 1.00 47.29  ? 62  ILE D CA  1 
ATOM   8640  C C   . ILE D 1 62  ? 126.463 103.174 153.439 1.00 47.29  ? 62  ILE D C   1 
ATOM   8641  O O   . ILE D 1 62  ? 125.911 104.188 153.877 1.00 47.29  ? 62  ILE D O   1 
ATOM   8642  C CB  . ILE D 1 62  ? 128.514 103.490 152.007 1.00 47.29  ? 62  ILE D CB  1 
ATOM   8643  C CG1 . ILE D 1 62  ? 128.746 104.797 152.756 1.00 47.29  ? 62  ILE D CG1 1 
ATOM   8644  C CG2 . ILE D 1 62  ? 129.005 103.620 150.583 1.00 47.29  ? 62  ILE D CG2 1 
ATOM   8645  C CD1 . ILE D 1 62  ? 130.180 105.242 152.750 1.00 47.29  ? 62  ILE D CD1 1 
ATOM   8646  N N   . PHE D 1 63  ? 126.597 102.056 154.149 1.00 47.29  ? 63  PHE D N   1 
ATOM   8647  C CA  . PHE D 1 63  ? 126.253 101.976 155.567 1.00 47.29  ? 63  PHE D CA  1 
ATOM   8648  C C   . PHE D 1 63  ? 127.525 102.100 156.402 1.00 47.29  ? 63  PHE D C   1 
ATOM   8649  O O   . PHE D 1 63  ? 127.995 101.146 157.016 1.00 47.29  ? 63  PHE D O   1 
ATOM   8650  C CB  . PHE D 1 63  ? 125.535 100.665 155.872 1.00 47.29  ? 63  PHE D CB  1 
ATOM   8651  C CG  . PHE D 1 63  ? 124.143 100.577 155.325 1.00 47.29  ? 63  PHE D CG  1 
ATOM   8652  C CD1 . PHE D 1 63  ? 123.590 101.615 154.606 1.00 47.29  ? 63  PHE D CD1 1 
ATOM   8653  C CD2 . PHE D 1 63  ? 123.385 99.442  155.540 1.00 47.29  ? 63  PHE D CD2 1 
ATOM   8654  C CE1 . PHE D 1 63  ? 122.312 101.517 154.109 1.00 47.29  ? 63  PHE D CE1 1 
ATOM   8655  C CE2 . PHE D 1 63  ? 122.108 99.341  155.046 1.00 47.29  ? 63  PHE D CE2 1 
ATOM   8656  C CZ  . PHE D 1 63  ? 121.570 100.380 154.330 1.00 47.29  ? 63  PHE D CZ  1 
ATOM   8657  N N   . LEU D 1 64  ? 128.092 103.301 156.407 1.00 36.28  ? 64  LEU D N   1 
ATOM   8658  C CA  . LEU D 1 64  ? 129.366 103.510 157.083 1.00 36.28  ? 64  LEU D CA  1 
ATOM   8659  C C   . LEU D 1 64  ? 129.226 103.255 158.578 1.00 36.28  ? 64  LEU D C   1 
ATOM   8660  O O   . LEU D 1 64  ? 128.413 103.894 159.250 1.00 36.28  ? 64  LEU D O   1 
ATOM   8661  C CB  . LEU D 1 64  ? 129.865 104.929 156.831 1.00 36.28  ? 64  LEU D CB  1 
ATOM   8662  C CG  . LEU D 1 64  ? 130.853 105.461 157.865 1.00 36.28  ? 64  LEU D CG  1 
ATOM   8663  C CD1 . LEU D 1 64  ? 132.208 104.814 157.668 1.00 36.28  ? 64  LEU D CD1 1 
ATOM   8664  C CD2 . LEU D 1 64  ? 130.956 106.969 157.771 1.00 36.28  ? 64  LEU D CD2 1 
ATOM   8665  N N   . ARG D 1 65  ? 130.017 102.318 159.095 1.00 37.33  ? 65  ARG D N   1 
ATOM   8666  C CA  . ARG D 1 65  ? 130.006 101.963 160.506 1.00 37.33  ? 65  ARG D CA  1 
ATOM   8667  C C   . ARG D 1 65  ? 131.333 102.330 161.153 1.00 37.33  ? 65  ARG D C   1 
ATOM   8668  O O   . ARG D 1 65  ? 132.389 102.257 160.523 1.00 37.33  ? 65  ARG D O   1 
ATOM   8669  C CB  . ARG D 1 65  ? 129.748 100.468 160.706 1.00 37.33  ? 65  ARG D CB  1 
ATOM   8670  C CG  . ARG D 1 65  ? 128.780 99.858  159.721 1.00 37.33  ? 65  ARG D CG  1 
ATOM   8671  C CD  . ARG D 1 65  ? 128.236 98.543  160.237 1.00 37.33  ? 65  ARG D CD  1 
ATOM   8672  N NE  . ARG D 1 65  ? 128.253 97.508  159.212 1.00 37.33  ? 65  ARG D NE  1 
ATOM   8673  C CZ  . ARG D 1 65  ? 127.241 97.247  158.397 1.00 37.33  ? 65  ARG D CZ  1 
ATOM   8674  N NH1 . ARG D 1 65  ? 126.112 97.932  158.457 1.00 37.33  ? 65  ARG D NH1 1 
ATOM   8675  N NH2 . ARG D 1 65  ? 127.366 96.273  157.501 1.00 37.33  ? 65  ARG D NH2 1 
ATOM   8676  N N   . GLN D 1 66  ? 131.272 102.723 162.423 1.00 47.29  ? 66  GLN D N   1 
ATOM   8677  C CA  . GLN D 1 66  ? 132.463 103.049 163.193 1.00 47.29  ? 66  GLN D CA  1 
ATOM   8678  C C   . GLN D 1 66  ? 132.372 102.392 164.558 1.00 47.29  ? 66  GLN D C   1 
ATOM   8679  O O   . GLN D 1 66  ? 131.281 102.259 165.116 1.00 47.29  ? 66  GLN D O   1 
ATOM   8680  C CB  . GLN D 1 66  ? 132.631 104.562 163.367 1.00 47.29  ? 66  GLN D CB  1 
ATOM   8681  C CG  . GLN D 1 66  ? 132.532 105.360 162.086 1.00 47.29  ? 66  GLN D CG  1 
ATOM   8682  C CD  . GLN D 1 66  ? 132.331 106.836 162.344 1.00 47.29  ? 66  GLN D CD  1 
ATOM   8683  O OE1 . GLN D 1 66  ? 133.040 107.437 163.146 1.00 47.29  ? 66  GLN D OE1 1 
ATOM   8684  N NE2 . GLN D 1 66  ? 131.356 107.427 161.668 1.00 47.29  ? 66  GLN D NE2 1 
ATOM   8685  N N   . LYS D 1 67  ? 133.517 101.982 165.094 1.00 44.39  ? 67  LYS D N   1 
ATOM   8686  C CA  . LYS D 1 67  ? 133.591 101.437 166.441 1.00 44.39  ? 67  LYS D CA  1 
ATOM   8687  C C   . LYS D 1 67  ? 134.739 102.087 167.194 1.00 44.39  ? 67  LYS D C   1 
ATOM   8688  O O   . LYS D 1 67  ? 135.773 102.413 166.604 1.00 44.39  ? 67  LYS D O   1 
ATOM   8689  C CB  . LYS D 1 67  ? 133.778 99.918  166.439 1.00 44.39  ? 67  LYS D CB  1 
ATOM   8690  C CG  . LYS D 1 67  ? 133.040 99.186  165.340 1.00 44.39  ? 67  LYS D CG  1 
ATOM   8691  C CD  . LYS D 1 67  ? 133.390 97.712  165.353 1.00 44.39  ? 67  LYS D CD  1 
ATOM   8692  C CE  . LYS D 1 67  ? 132.809 96.994  164.152 1.00 44.39  ? 67  LYS D CE  1 
ATOM   8693  N NZ  . LYS D 1 67  ? 133.054 95.530  164.231 1.00 44.39  ? 67  LYS D NZ  1 
ATOM   8694  N N   . TRP D 1 68  ? 134.553 102.276 168.497 1.00 47.29  ? 68  TRP D N   1 
ATOM   8695  C CA  . TRP D 1 68  ? 135.609 102.799 169.351 1.00 47.29  ? 68  TRP D CA  1 
ATOM   8696  C C   . TRP D 1 68  ? 135.276 102.462 170.794 1.00 47.29  ? 68  TRP D C   1 
ATOM   8697  O O   . TRP D 1 68  ? 134.130 102.156 171.129 1.00 47.29  ? 68  TRP D O   1 
ATOM   8698  C CB  . TRP D 1 68  ? 135.785 104.310 169.179 1.00 47.29  ? 68  TRP D CB  1 
ATOM   8699  C CG  . TRP D 1 68  ? 134.661 105.123 169.728 1.00 47.29  ? 68  TRP D CG  1 
ATOM   8700  C CD1 . TRP D 1 68  ? 134.570 105.650 170.980 1.00 47.29  ? 68  TRP D CD1 1 
ATOM   8701  C CD2 . TRP D 1 68  ? 133.469 105.514 169.040 1.00 47.29  ? 68  TRP D CD2 1 
ATOM   8702  N NE1 . TRP D 1 68  ? 133.393 106.342 171.118 1.00 47.29  ? 68  TRP D NE1 1 
ATOM   8703  C CE2 . TRP D 1 68  ? 132.699 106.273 169.939 1.00 47.29  ? 68  TRP D CE2 1 
ATOM   8704  C CE3 . TRP D 1 68  ? 132.977 105.294 167.753 1.00 47.29  ? 68  TRP D CE3 1 
ATOM   8705  C CZ2 . TRP D 1 68  ? 131.466 106.811 169.593 1.00 47.29  ? 68  TRP D CZ2 1 
ATOM   8706  C CZ3 . TRP D 1 68  ? 131.754 105.831 167.412 1.00 47.29  ? 68  TRP D CZ3 1 
ATOM   8707  C CH2 . TRP D 1 68  ? 131.012 106.580 168.327 1.00 47.29  ? 68  TRP D CH2 1 
ATOM   8708  N N   . ASN D 1 69  ? 136.292 102.523 171.645 1.00 47.37  ? 69  ASN D N   1 
ATOM   8709  C CA  . ASN D 1 69  ? 136.134 102.232 173.060 1.00 47.37  ? 69  ASN D CA  1 
ATOM   8710  C C   . ASN D 1 69  ? 135.956 103.525 173.844 1.00 47.37  ? 69  ASN D C   1 
ATOM   8711  O O   . ASN D 1 69  ? 136.483 104.576 173.472 1.00 47.37  ? 69  ASN D O   1 
ATOM   8712  C CB  . ASN D 1 69  ? 137.337 101.456 173.598 1.00 47.37  ? 69  ASN D CB  1 
ATOM   8713  C CG  . ASN D 1 69  ? 137.126 100.961 175.014 1.00 47.37  ? 69  ASN D CG  1 
ATOM   8714  O OD1 . ASN D 1 69  ? 136.059 101.149 175.597 1.00 47.37  ? 69  ASN D OD1 1 
ATOM   8715  N ND2 . ASN D 1 69  ? 138.143 100.320 175.574 1.00 47.37  ? 69  ASN D ND2 1 
ATOM   8716  N N   . ASP D 1 70  ? 135.204 103.437 174.933 1.00 52.40  ? 70  ASP D N   1 
ATOM   8717  C CA  . ASP D 1 70  ? 134.939 104.598 175.770 1.00 52.40  ? 70  ASP D CA  1 
ATOM   8718  C C   . ASP D 1 70  ? 134.687 104.155 177.205 1.00 52.40  ? 70  ASP D C   1 
ATOM   8719  O O   . ASP D 1 70  ? 133.609 103.631 177.512 1.00 52.40  ? 70  ASP D O   1 
ATOM   8720  C CB  . ASP D 1 70  ? 133.745 105.385 175.232 1.00 52.40  ? 70  ASP D CB  1 
ATOM   8721  C CG  . ASP D 1 70  ? 133.695 106.802 175.757 1.00 52.40  ? 70  ASP D CG  1 
ATOM   8722  O OD1 . ASP D 1 70  ? 134.135 107.034 176.902 1.00 52.40  ? 70  ASP D OD1 1 
ATOM   8723  O OD2 . ASP D 1 70  ? 133.214 107.689 175.023 1.00 52.40  ? 70  ASP D OD2 1 
ATOM   8724  N N   . PRO D 1 71  ? 135.649 104.345 178.109 1.00 55.60  ? 71  PRO D N   1 
ATOM   8725  C CA  . PRO D 1 71  ? 135.438 103.925 179.503 1.00 55.60  ? 71  PRO D CA  1 
ATOM   8726  C C   . PRO D 1 71  ? 134.305 104.659 180.196 1.00 55.60  ? 71  PRO D C   1 
ATOM   8727  O O   . PRO D 1 71  ? 133.743 104.126 181.160 1.00 55.60  ? 71  PRO D O   1 
ATOM   8728  C CB  . PRO D 1 71  ? 136.788 104.224 180.168 1.00 55.60  ? 71  PRO D CB  1 
ATOM   8729  C CG  . PRO D 1 71  ? 137.401 105.282 179.315 1.00 55.60  ? 71  PRO D CG  1 
ATOM   8730  C CD  . PRO D 1 71  ? 136.960 104.984 177.914 1.00 55.60  ? 71  PRO D CD  1 
ATOM   8731  N N   . ARG D 1 72  ? 133.948 105.860 179.741 1.00 55.54  ? 72  ARG D N   1 
ATOM   8732  C CA  . ARG D 1 72  ? 132.869 106.606 180.374 1.00 55.54  ? 72  ARG D CA  1 
ATOM   8733  C C   . ARG D 1 72  ? 131.494 106.035 180.063 1.00 55.54  ? 72  ARG D C   1 
ATOM   8734  O O   . ARG D 1 72  ? 130.516 106.447 180.696 1.00 55.54  ? 72  ARG D O   1 
ATOM   8735  C CB  . ARG D 1 72  ? 132.928 108.073 179.949 1.00 55.54  ? 72  ARG D CB  1 
ATOM   8736  C CG  . ARG D 1 72  ? 134.235 108.758 180.302 1.00 55.54  ? 72  ARG D CG  1 
ATOM   8737  C CD  . ARG D 1 72  ? 134.249 110.198 179.831 1.00 55.54  ? 72  ARG D CD  1 
ATOM   8738  N NE  . ARG D 1 72  ? 133.933 110.308 178.413 1.00 55.54  ? 72  ARG D NE  1 
ATOM   8739  C CZ  . ARG D 1 72  ? 134.019 111.430 177.713 1.00 55.54  ? 72  ARG D CZ  1 
ATOM   8740  N NH1 . ARG D 1 72  ? 134.406 112.564 178.272 1.00 55.54  ? 72  ARG D NH1 1 
ATOM   8741  N NH2 . ARG D 1 72  ? 133.708 111.413 176.421 1.00 55.54  ? 72  ARG D NH2 1 
ATOM   8742  N N   . LEU D 1 73  ? 131.393 105.107 179.116 1.00 53.43  ? 73  LEU D N   1 
ATOM   8743  C CA  . LEU D 1 73  ? 130.130 104.481 178.742 1.00 53.43  ? 73  LEU D CA  1 
ATOM   8744  C C   . LEU D 1 73  ? 130.110 103.004 179.121 1.00 53.43  ? 73  LEU D C   1 
ATOM   8745  O O   . LEU D 1 73  ? 129.580 102.166 178.392 1.00 53.43  ? 73  LEU D O   1 
ATOM   8746  C CB  . LEU D 1 73  ? 129.863 104.651 177.250 1.00 53.43  ? 73  LEU D CB  1 
ATOM   8747  C CG  . LEU D 1 73  ? 128.778 105.656 176.869 1.00 53.43  ? 73  LEU D CG  1 
ATOM   8748  C CD1 . LEU D 1 73  ? 129.021 106.981 177.561 1.00 53.43  ? 73  LEU D CD1 1 
ATOM   8749  C CD2 . LEU D 1 73  ? 128.735 105.840 175.366 1.00 53.43  ? 73  LEU D CD2 1 
ATOM   8750  N N   . ALA D 1 74  ? 130.694 102.671 180.267 1.00 58.89  ? 74  ALA D N   1 
ATOM   8751  C CA  . ALA D 1 74  ? 130.709 101.305 180.769 1.00 58.89  ? 74  ALA D CA  1 
ATOM   8752  C C   . ALA D 1 74  ? 129.647 101.156 181.848 1.00 58.89  ? 74  ALA D C   1 
ATOM   8753  O O   . ALA D 1 74  ? 129.640 101.909 182.827 1.00 58.89  ? 74  ALA D O   1 
ATOM   8754  C CB  . ALA D 1 74  ? 132.085 100.941 181.326 1.00 58.89  ? 74  ALA D CB  1 
ATOM   8755  N N   . TYR D 1 75  ? 128.758 100.184 181.668 1.00 62.11  ? 75  TYR D N   1 
ATOM   8756  C CA  . TYR D 1 75  ? 127.652 99.957  182.584 1.00 62.11  ? 75  TYR D CA  1 
ATOM   8757  C C   . TYR D 1 75  ? 127.678 98.516  183.067 1.00 62.11  ? 75  TYR D C   1 
ATOM   8758  O O   . TYR D 1 75  ? 128.137 97.616  182.359 1.00 62.11  ? 75  TYR D O   1 
ATOM   8759  C CB  . TYR D 1 75  ? 126.305 100.257 181.919 1.00 62.11  ? 75  TYR D CB  1 
ATOM   8760  C CG  . TYR D 1 75  ? 125.955 99.298  180.809 1.00 62.11  ? 75  TYR D CG  1 
ATOM   8761  C CD1 . TYR D 1 75  ? 126.482 99.458  179.537 1.00 62.11  ? 75  TYR D CD1 1 
ATOM   8762  C CD2 . TYR D 1 75  ? 125.099 98.231  181.033 1.00 62.11  ? 75  TYR D CD2 1 
ATOM   8763  C CE1 . TYR D 1 75  ? 126.166 98.583  178.520 1.00 62.11  ? 75  TYR D CE1 1 
ATOM   8764  C CE2 . TYR D 1 75  ? 124.778 97.351  180.022 1.00 62.11  ? 75  TYR D CE2 1 
ATOM   8765  C CZ  . TYR D 1 75  ? 125.314 97.532  178.768 1.00 62.11  ? 75  TYR D CZ  1 
ATOM   8766  O OH  . TYR D 1 75  ? 124.995 96.655  177.758 1.00 62.11  ? 75  TYR D OH  1 
ATOM   8767  N N   . SER D 1 76  ? 127.176 98.306  184.284 1.00 72.76  ? 76  SER D N   1 
ATOM   8768  C CA  . SER D 1 76  ? 127.123 96.978  184.873 1.00 72.76  ? 76  SER D CA  1 
ATOM   8769  C C   . SER D 1 76  ? 125.771 96.639  185.484 1.00 72.76  ? 76  SER D C   1 
ATOM   8770  O O   . SER D 1 76  ? 125.600 95.519  185.977 1.00 72.76  ? 76  SER D O   1 
ATOM   8771  C CB  . SER D 1 76  ? 128.212 96.823  185.945 1.00 72.76  ? 76  SER D CB  1 
ATOM   8772  O OG  . SER D 1 76  ? 127.976 97.695  187.034 1.00 72.76  ? 76  SER D OG  1 
ATOM   8773  N N   . GLU D 1 77  ? 124.812 97.565  185.473 1.00 75.17  ? 77  GLU D N   1 
ATOM   8774  C CA  . GLU D 1 77  ? 123.503 97.282  186.052 1.00 75.17  ? 77  GLU D CA  1 
ATOM   8775  C C   . GLU D 1 77  ? 122.737 96.263  185.217 1.00 75.17  ? 77  GLU D C   1 
ATOM   8776  O O   . GLU D 1 77  ? 122.173 95.303  185.754 1.00 75.17  ? 77  GLU D O   1 
ATOM   8777  C CB  . GLU D 1 77  ? 122.702 98.577  186.191 1.00 75.17  ? 77  GLU D CB  1 
ATOM   8778  N N   . TYR D 1 78  ? 122.706 96.453  183.904 1.00 74.65  ? 78  TYR D N   1 
ATOM   8779  C CA  . TYR D 1 78  ? 121.950 95.562  183.034 1.00 74.65  ? 78  TYR D CA  1 
ATOM   8780  C C   . TYR D 1 78  ? 122.766 94.313  182.724 1.00 74.65  ? 78  TYR D C   1 
ATOM   8781  O O   . TYR D 1 78  ? 123.896 94.431  182.238 1.00 74.65  ? 78  TYR D O   1 
ATOM   8782  C CB  . TYR D 1 78  ? 121.565 96.272  181.745 1.00 74.65  ? 78  TYR D CB  1 
ATOM   8783  C CG  . TYR D 1 78  ? 120.217 96.952  181.804 1.00 74.65  ? 78  TYR D CG  1 
ATOM   8784  C CD1 . TYR D 1 78  ? 119.425 96.865  182.939 1.00 74.65  ? 78  TYR D CD1 1 
ATOM   8785  C CD2 . TYR D 1 78  ? 119.735 97.676  180.724 1.00 74.65  ? 78  TYR D CD2 1 
ATOM   8786  C CE1 . TYR D 1 78  ? 118.192 97.484  182.998 1.00 74.65  ? 78  TYR D CE1 1 
ATOM   8787  C CE2 . TYR D 1 78  ? 118.504 98.298  180.774 1.00 74.65  ? 78  TYR D CE2 1 
ATOM   8788  C CZ  . TYR D 1 78  ? 117.737 98.198  181.912 1.00 74.65  ? 78  TYR D CZ  1 
ATOM   8789  O OH  . TYR D 1 78  ? 116.510 98.816  181.965 1.00 74.65  ? 78  TYR D OH  1 
ATOM   8790  N N   . PRO D 1 79  ? 122.246 93.114  182.995 1.00 81.69  ? 79  PRO D N   1 
ATOM   8791  C CA  . PRO D 1 79  ? 123.003 91.896  182.664 1.00 81.69  ? 79  PRO D CA  1 
ATOM   8792  C C   . PRO D 1 79  ? 123.261 91.724  181.178 1.00 81.69  ? 79  PRO D C   1 
ATOM   8793  O O   . PRO D 1 79  ? 124.286 91.142  180.801 1.00 81.69  ? 79  PRO D O   1 
ATOM   8794  C CB  . PRO D 1 79  ? 122.114 90.774  183.216 1.00 81.69  ? 79  PRO D CB  1 
ATOM   8795  C CG  . PRO D 1 79  ? 120.739 91.353  183.215 1.00 81.69  ? 79  PRO D CG  1 
ATOM   8796  C CD  . PRO D 1 79  ? 120.914 92.808  183.542 1.00 81.69  ? 79  PRO D CD  1 
ATOM   8797  N N   . ASP D 1 80  ? 122.359 92.203  180.323 1.00 74.75  ? 80  ASP D N   1 
ATOM   8798  C CA  . ASP D 1 80  ? 122.529 92.035  178.886 1.00 74.75  ? 80  ASP D CA  1 
ATOM   8799  C C   . ASP D 1 80  ? 123.762 92.787  178.401 1.00 74.75  ? 80  ASP D C   1 
ATOM   8800  O O   . ASP D 1 80  ? 124.001 93.937  178.781 1.00 74.75  ? 80  ASP D O   1 
ATOM   8801  C CB  . ASP D 1 80  ? 121.284 92.526  178.146 1.00 74.75  ? 80  ASP D CB  1 
ATOM   8802  C CG  . ASP D 1 80  ? 121.170 91.948  176.749 1.00 74.75  ? 80  ASP D CG  1 
ATOM   8803  O OD1 . ASP D 1 80  ? 121.978 91.061  176.404 1.00 74.75  ? 80  ASP D OD1 1 
ATOM   8804  O OD2 . ASP D 1 80  ? 120.273 92.381  175.996 1.00 74.75  ? 80  ASP D OD2 1 
ATOM   8805  N N   . ASP D 1 81  ? 124.552 92.124  177.554 1.00 65.35  ? 81  ASP D N   1 
ATOM   8806  C CA  . ASP D 1 81  ? 125.803 92.718  177.094 1.00 65.35  ? 81  ASP D CA  1 
ATOM   8807  C C   . ASP D 1 81  ? 125.556 93.855  176.111 1.00 65.35  ? 81  ASP D C   1 
ATOM   8808  O O   . ASP D 1 81  ? 126.175 94.919  176.220 1.00 65.35  ? 81  ASP D O   1 
ATOM   8809  C CB  . ASP D 1 81  ? 126.688 91.646  176.463 1.00 65.35  ? 81  ASP D CB  1 
ATOM   8810  C CG  . ASP D 1 81  ? 125.902 90.674  175.610 1.00 65.35  ? 81  ASP D CG  1 
ATOM   8811  O OD1 . ASP D 1 81  ? 124.703 90.930  175.372 1.00 65.35  ? 81  ASP D OD1 1 
ATOM   8812  O OD2 . ASP D 1 81  ? 126.481 89.656  175.179 1.00 65.35  ? 81  ASP D OD2 1 
ATOM   8813  N N   . SER D 1 82  ? 124.656 93.658  175.153 1.00 58.37  ? 82  SER D N   1 
ATOM   8814  C CA  . SER D 1 82  ? 124.390 94.640  174.110 1.00 58.37  ? 82  SER D CA  1 
ATOM   8815  C C   . SER D 1 82  ? 123.054 95.319  174.374 1.00 58.37  ? 82  SER D C   1 
ATOM   8816  O O   . SER D 1 82  ? 122.042 94.644  174.586 1.00 58.37  ? 82  SER D O   1 
ATOM   8817  C CB  . SER D 1 82  ? 124.380 93.982  172.729 1.00 58.37  ? 82  SER D CB  1 
ATOM   8818  O OG  . SER D 1 82  ? 125.607 93.326  172.469 1.00 58.37  ? 82  SER D OG  1 
ATOM   8819  N N   . LEU D 1 83  ? 123.056 96.647  174.357 1.00 50.11  ? 83  LEU D N   1 
ATOM   8820  C CA  . LEU D 1 83  ? 121.851 97.446  174.568 1.00 50.11  ? 83  LEU D CA  1 
ATOM   8821  C C   . LEU D 1 83  ? 121.584 98.249  173.301 1.00 50.11  ? 83  LEU D C   1 
ATOM   8822  O O   . LEU D 1 83  ? 122.208 99.289  173.075 1.00 50.11  ? 83  LEU D O   1 
ATOM   8823  C CB  . LEU D 1 83  ? 122.004 98.364  175.775 1.00 50.11  ? 83  LEU D CB  1 
ATOM   8824  C CG  . LEU D 1 83  ? 122.013 97.711  177.154 1.00 50.11  ? 83  LEU D CG  1 
ATOM   8825  C CD1 . LEU D 1 83  ? 122.026 98.782  178.229 1.00 50.11  ? 83  LEU D CD1 1 
ATOM   8826  C CD2 . LEU D 1 83  ? 120.816 96.790  177.319 1.00 50.11  ? 83  LEU D CD2 1 
ATOM   8827  N N   . ASP D 1 84  ? 120.654 97.774  172.481 1.00 47.12  ? 84  ASP D N   1 
ATOM   8828  C CA  . ASP D 1 84  ? 120.278 98.481  171.261 1.00 47.12  ? 84  ASP D CA  1 
ATOM   8829  C C   . ASP D 1 84  ? 119.443 99.693  171.646 1.00 47.12  ? 84  ASP D C   1 
ATOM   8830  O O   . ASP D 1 84  ? 118.231 99.592  171.844 1.00 47.12  ? 84  ASP D O   1 
ATOM   8831  C CB  . ASP D 1 84  ? 119.514 97.555  170.323 1.00 47.12  ? 84  ASP D CB  1 
ATOM   8832  C CG  . ASP D 1 84  ? 119.438 98.092  168.912 1.00 47.12  ? 84  ASP D CG  1 
ATOM   8833  O OD1 . ASP D 1 84  ? 118.904 99.204  168.724 1.00 47.12  ? 84  ASP D OD1 1 
ATOM   8834  O OD2 . ASP D 1 84  ? 119.918 97.402  167.989 1.00 47.12  ? 84  ASP D OD2 1 
ATOM   8835  N N   . LEU D 1 85  ? 120.087 100.848 171.751 1.00 42.51  ? 85  LEU D N   1 
ATOM   8836  C CA  . LEU D 1 85  ? 119.424 102.050 172.228 1.00 42.51  ? 85  LEU D CA  1 
ATOM   8837  C C   . LEU D 1 85  ? 118.817 102.833 171.069 1.00 42.51  ? 85  LEU D C   1 
ATOM   8838  O O   . LEU D 1 85  ? 119.112 102.591 169.896 1.00 42.51  ? 85  LEU D O   1 
ATOM   8839  C CB  . LEU D 1 85  ? 120.400 102.933 172.999 1.00 42.51  ? 85  LEU D CB  1 
ATOM   8840  C CG  . LEU D 1 85  ? 121.179 102.292 174.148 1.00 42.51  ? 85  LEU D CG  1 
ATOM   8841  C CD1 . LEU D 1 85  ? 121.816 103.356 175.022 1.00 42.51  ? 85  LEU D CD1 1 
ATOM   8842  C CD2 . LEU D 1 85  ? 120.274 101.404 174.976 1.00 42.51  ? 85  LEU D CD2 1 
ATOM   8843  N N   . ASP D 1 86  ? 117.954 103.779 171.419 1.00 48.01  ? 86  ASP D N   1 
ATOM   8844  C CA  . ASP D 1 86  ? 117.276 104.579 170.413 1.00 48.01  ? 86  ASP D CA  1 
ATOM   8845  C C   . ASP D 1 86  ? 118.287 105.442 169.661 1.00 48.01  ? 86  ASP D C   1 
ATOM   8846  O O   . ASP D 1 86  ? 119.237 105.953 170.264 1.00 48.01  ? 86  ASP D O   1 
ATOM   8847  C CB  . ASP D 1 86  ? 116.209 105.459 171.068 1.00 48.01  ? 86  ASP D CB  1 
ATOM   8848  C CG  . ASP D 1 86  ? 115.253 106.068 170.062 1.00 48.01  ? 86  ASP D CG  1 
ATOM   8849  O OD1 . ASP D 1 86  ? 114.474 105.313 169.443 1.00 48.01  ? 86  ASP D OD1 1 
ATOM   8850  O OD2 . ASP D 1 86  ? 115.277 107.305 169.894 1.00 48.01  ? 86  ASP D OD2 1 
ATOM   8851  N N   . PRO D 1 87  ? 118.115 105.625 168.350 1.00 45.11  ? 87  PRO D N   1 
ATOM   8852  C CA  . PRO D 1 87  ? 119.084 106.427 167.587 1.00 45.11  ? 87  PRO D CA  1 
ATOM   8853  C C   . PRO D 1 87  ? 119.171 107.876 168.029 1.00 45.11  ? 87  PRO D C   1 
ATOM   8854  O O   . PRO D 1 87  ? 120.163 108.543 167.710 1.00 45.11  ? 87  PRO D O   1 
ATOM   8855  C CB  . PRO D 1 87  ? 118.570 106.318 166.146 1.00 45.11  ? 87  PRO D CB  1 
ATOM   8856  C CG  . PRO D 1 87  ? 117.769 105.066 166.121 1.00 45.11  ? 87  PRO D CG  1 
ATOM   8857  C CD  . PRO D 1 87  ? 117.141 104.955 167.474 1.00 45.11  ? 87  PRO D CD  1 
ATOM   8858  N N   . SER D 1 88  ? 118.170 108.391 168.743 1.00 52.58  ? 88  SER D N   1 
ATOM   8859  C CA  . SER D 1 88  ? 118.176 109.795 169.133 1.00 52.58  ? 88  SER D CA  1 
ATOM   8860  C C   . SER D 1 88  ? 119.246 110.124 170.167 1.00 52.58  ? 88  SER D C   1 
ATOM   8861  O O   . SER D 1 88  ? 119.563 111.305 170.343 1.00 52.58  ? 88  SER D O   1 
ATOM   8862  C CB  . SER D 1 88  ? 116.802 110.193 169.671 1.00 52.58  ? 88  SER D CB  1 
ATOM   8863  O OG  . SER D 1 88  ? 116.797 111.544 170.094 1.00 52.58  ? 88  SER D OG  1 
ATOM   8864  N N   . MET D 1 89  ? 119.809 109.123 170.848 1.00 54.36  ? 89  MET D N   1 
ATOM   8865  C CA  . MET D 1 89  ? 120.821 109.383 171.865 1.00 54.36  ? 89  MET D CA  1 
ATOM   8866  C C   . MET D 1 89  ? 122.114 109.932 171.281 1.00 54.36  ? 89  MET D C   1 
ATOM   8867  O O   . MET D 1 89  ? 122.898 110.545 172.013 1.00 54.36  ? 89  MET D O   1 
ATOM   8868  C CB  . MET D 1 89  ? 121.148 108.102 172.635 1.00 54.36  ? 89  MET D CB  1 
ATOM   8869  C CG  . MET D 1 89  ? 120.006 107.397 173.370 1.00 54.36  ? 89  MET D CG  1 
ATOM   8870  S SD  . MET D 1 89  ? 118.831 108.326 174.378 1.00 54.36  ? 89  MET D SD  1 
ATOM   8871  C CE  . MET D 1 89  ? 119.808 109.674 175.047 1.00 54.36  ? 89  MET D CE  1 
ATOM   8872  N N   . LEU D 1 90  ? 122.348 109.736 169.982 1.00 49.74  ? 90  LEU D N   1 
ATOM   8873  C CA  . LEU D 1 90  ? 123.664 109.984 169.405 1.00 49.74  ? 90  LEU D CA  1 
ATOM   8874  C C   . LEU D 1 90  ? 124.090 111.442 169.508 1.00 49.74  ? 90  LEU D C   1 
ATOM   8875  O O   . LEU D 1 90  ? 125.279 111.738 169.359 1.00 49.74  ? 90  LEU D O   1 
ATOM   8876  C CB  . LEU D 1 90  ? 123.680 109.537 167.948 1.00 49.74  ? 90  LEU D CB  1 
ATOM   8877  C CG  . LEU D 1 90  ? 123.489 108.034 167.782 1.00 49.74  ? 90  LEU D CG  1 
ATOM   8878  C CD1 . LEU D 1 90  ? 123.495 107.668 166.319 1.00 49.74  ? 90  LEU D CD1 1 
ATOM   8879  C CD2 . LEU D 1 90  ? 124.566 107.280 168.532 1.00 49.74  ? 90  LEU D CD2 1 
ATOM   8880  N N   . ASP D 1 91  ? 123.153 112.359 169.744 1.00 57.36  ? 91  ASP D N   1 
ATOM   8881  C CA  . ASP D 1 91  ? 123.535 113.744 169.966 1.00 57.36  ? 91  ASP D CA  1 
ATOM   8882  C C   . ASP D 1 91  ? 124.143 113.960 171.344 1.00 57.36  ? 91  ASP D C   1 
ATOM   8883  O O   . ASP D 1 91  ? 124.829 114.966 171.554 1.00 57.36  ? 91  ASP D O   1 
ATOM   8884  C CB  . ASP D 1 91  ? 122.325 114.661 169.782 1.00 57.36  ? 91  ASP D CB  1 
ATOM   8885  C CG  . ASP D 1 91  ? 121.682 114.505 168.419 1.00 57.36  ? 91  ASP D CG  1 
ATOM   8886  O OD1 . ASP D 1 91  ? 121.057 113.453 168.172 1.00 57.36  ? 91  ASP D OD1 1 
ATOM   8887  O OD2 . ASP D 1 91  ? 121.804 115.434 167.594 1.00 57.36  ? 91  ASP D OD2 1 
ATOM   8888  N N   . SER D 1 92  ? 123.918 113.043 172.282 1.00 56.60  ? 92  SER D N   1 
ATOM   8889  C CA  . SER D 1 92  ? 124.355 113.212 173.660 1.00 56.60  ? 92  SER D CA  1 
ATOM   8890  C C   . SER D 1 92  ? 125.649 112.478 173.984 1.00 56.60  ? 92  SER D C   1 
ATOM   8891  O O   . SER D 1 92  ? 126.082 112.506 175.139 1.00 56.60  ? 92  SER D O   1 
ATOM   8892  C CB  . SER D 1 92  ? 123.255 112.754 174.620 1.00 56.60  ? 92  SER D CB  1 
ATOM   8893  O OG  . SER D 1 92  ? 123.657 112.924 175.967 1.00 56.60  ? 92  SER D OG  1 
ATOM   8894  N N   . ILE D 1 93  ? 126.276 111.824 173.010 1.00 49.18  ? 93  ILE D N   1 
ATOM   8895  C CA  . ILE D 1 93  ? 127.533 111.126 173.236 1.00 49.18  ? 93  ILE D CA  1 
ATOM   8896  C C   . ILE D 1 93  ? 128.574 111.665 172.265 1.00 49.18  ? 93  ILE D C   1 
ATOM   8897  O O   . ILE D 1 93  ? 128.253 112.272 171.241 1.00 49.18  ? 93  ILE D O   1 
ATOM   8898  C CB  . ILE D 1 93  ? 127.399 109.597 173.087 1.00 49.18  ? 93  ILE D CB  1 
ATOM   8899  C CG1 . ILE D 1 93  ? 127.244 109.215 171.616 1.00 49.18  ? 93  ILE D CG1 1 
ATOM   8900  C CG2 . ILE D 1 93  ? 126.226 109.082 173.894 1.00 49.18  ? 93  ILE D CG2 1 
ATOM   8901  C CD1 . ILE D 1 93  ? 127.150 107.727 171.382 1.00 49.18  ? 93  ILE D CD1 1 
ATOM   8902  N N   . TRP D 1 94  ? 129.839 111.441 172.607 1.00 47.30  ? 94  TRP D N   1 
ATOM   8903  C CA  . TRP D 1 94  ? 130.931 111.885 171.753 1.00 47.30  ? 94  TRP D CA  1 
ATOM   8904  C C   . TRP D 1 94  ? 130.956 111.068 170.471 1.00 47.30  ? 94  TRP D C   1 
ATOM   8905  O O   . TRP D 1 94  ? 130.859 109.838 170.505 1.00 47.30  ? 94  TRP D O   1 
ATOM   8906  C CB  . TRP D 1 94  ? 132.263 111.754 172.485 1.00 47.30  ? 94  TRP D CB  1 
ATOM   8907  C CG  . TRP D 1 94  ? 133.433 112.231 171.688 1.00 47.30  ? 94  TRP D CG  1 
ATOM   8908  C CD1 . TRP D 1 94  ? 133.834 113.521 171.517 1.00 47.30  ? 94  TRP D CD1 1 
ATOM   8909  C CD2 . TRP D 1 94  ? 134.357 111.423 170.952 1.00 47.30  ? 94  TRP D CD2 1 
ATOM   8910  N NE1 . TRP D 1 94  ? 134.952 113.569 170.723 1.00 47.30  ? 94  TRP D NE1 1 
ATOM   8911  C CE2 . TRP D 1 94  ? 135.293 112.292 170.363 1.00 47.30  ? 94  TRP D CE2 1 
ATOM   8912  C CE3 . TRP D 1 94  ? 134.483 110.050 170.734 1.00 47.30  ? 94  TRP D CE3 1 
ATOM   8913  C CZ2 . TRP D 1 94  ? 136.340 111.834 169.571 1.00 47.30  ? 94  TRP D CZ2 1 
ATOM   8914  C CZ3 . TRP D 1 94  ? 135.525 109.598 169.949 1.00 47.30  ? 94  TRP D CZ3 1 
ATOM   8915  C CH2 . TRP D 1 94  ? 136.438 110.487 169.376 1.00 47.30  ? 94  TRP D CH2 1 
ATOM   8916  N N   . LYS D 1 95  ? 131.085 111.750 169.338 1.00 42.78  ? 95  LYS D N   1 
ATOM   8917  C CA  . LYS D 1 95  ? 131.163 111.096 168.048 1.00 42.78  ? 95  LYS D CA  1 
ATOM   8918  C C   . LYS D 1 95  ? 132.450 111.505 167.346 1.00 42.78  ? 95  LYS D C   1 
ATOM   8919  O O   . LYS D 1 95  ? 132.759 112.703 167.282 1.00 42.78  ? 95  LYS D O   1 
ATOM   8920  C CB  . LYS D 1 95  ? 129.956 111.454 167.175 1.00 42.78  ? 95  LYS D CB  1 
ATOM   8921  C CG  . LYS D 1 95  ? 128.632 110.982 167.734 1.00 42.78  ? 95  LYS D CG  1 
ATOM   8922  C CD  . LYS D 1 95  ? 127.480 111.450 166.867 1.00 42.78  ? 95  LYS D CD  1 
ATOM   8923  C CE  . LYS D 1 95  ? 127.469 112.962 166.736 1.00 42.78  ? 95  LYS D CE  1 
ATOM   8924  N NZ  . LYS D 1 95  ? 126.272 113.443 165.995 1.00 42.78  ? 95  LYS D NZ  1 
ATOM   8925  N N   . PRO D 1 96  ? 133.225 110.560 166.818 1.00 38.66  ? 96  PRO D N   1 
ATOM   8926  C CA  . PRO D 1 96  ? 134.472 110.929 166.140 1.00 38.66  ? 96  PRO D CA  1 
ATOM   8927  C C   . PRO D 1 96  ? 134.187 111.562 164.787 1.00 38.66  ? 96  PRO D C   1 
ATOM   8928  O O   . PRO D 1 96  ? 133.407 111.035 163.991 1.00 38.66  ? 96  PRO D O   1 
ATOM   8929  C CB  . PRO D 1 96  ? 135.205 109.593 165.999 1.00 38.66  ? 96  PRO D CB  1 
ATOM   8930  C CG  . PRO D 1 96  ? 134.119 108.587 165.946 1.00 38.66  ? 96  PRO D CG  1 
ATOM   8931  C CD  . PRO D 1 96  ? 132.998 109.106 166.805 1.00 38.66  ? 96  PRO D CD  1 
ATOM   8932  N N   . ASP D 1 97  ? 134.820 112.704 164.539 1.00 37.85  ? 97  ASP D N   1 
ATOM   8933  C CA  . ASP D 1 97  ? 134.681 113.375 163.256 1.00 37.85  ? 97  ASP D CA  1 
ATOM   8934  C C   . ASP D 1 97  ? 135.247 112.502 162.146 1.00 37.85  ? 97  ASP D C   1 
ATOM   8935  O O   . ASP D 1 97  ? 136.309 111.893 162.293 1.00 37.85  ? 97  ASP D O   1 
ATOM   8936  C CB  . ASP D 1 97  ? 135.398 114.723 163.290 1.00 37.85  ? 97  ASP D CB  1 
ATOM   8937  C CG  . ASP D 1 97  ? 135.223 115.514 162.010 1.00 37.85  ? 97  ASP D CG  1 
ATOM   8938  O OD1 . ASP D 1 97  ? 134.393 115.119 161.166 1.00 37.85  ? 97  ASP D OD1 1 
ATOM   8939  O OD2 . ASP D 1 97  ? 135.918 116.538 161.848 1.00 37.85  ? 97  ASP D OD2 1 
ATOM   8940  N N   . LEU D 1 98  ? 134.530 112.439 161.027 1.00 34.81  ? 98  LEU D N   1 
ATOM   8941  C CA  . LEU D 1 98  ? 134.952 111.600 159.909 1.00 34.81  ? 98  LEU D CA  1 
ATOM   8942  C C   . LEU D 1 98  ? 134.326 112.155 158.639 1.00 34.81  ? 98  LEU D C   1 
ATOM   8943  O O   . LEU D 1 98  ? 133.122 111.992 158.424 1.00 34.81  ? 98  LEU D O   1 
ATOM   8944  C CB  . LEU D 1 98  ? 134.540 110.152 160.138 1.00 34.81  ? 98  LEU D CB  1 
ATOM   8945  C CG  . LEU D 1 98  ? 135.096 109.090 159.191 1.00 34.81  ? 98  LEU D CG  1 
ATOM   8946  C CD1 . LEU D 1 98  ? 135.320 107.793 159.939 1.00 34.81  ? 98  LEU D CD1 1 
ATOM   8947  C CD2 . LEU D 1 98  ? 134.159 108.864 158.021 1.00 34.81  ? 98  LEU D CD2 1 
ATOM   8948  N N   . PHE D 1 99  ? 135.134 112.789 157.799 1.00 33.80  ? 99  PHE D N   1 
ATOM   8949  C CA  . PHE D 1 99  ? 134.662 113.327 156.535 1.00 33.80  ? 99  PHE D CA  1 
ATOM   8950  C C   . PHE D 1 99  ? 135.449 112.713 155.390 1.00 33.80  ? 99  PHE D C   1 
ATOM   8951  O O   . PHE D 1 99  ? 136.639 112.414 155.523 1.00 33.80  ? 99  PHE D O   1 
ATOM   8952  C CB  . PHE D 1 99  ? 134.782 114.852 156.495 1.00 33.80  ? 99  PHE D CB  1 
ATOM   8953  C CG  . PHE D 1 99  ? 136.104 115.344 155.988 1.00 33.80  ? 99  PHE D CG  1 
ATOM   8954  C CD1 . PHE D 1 99  ? 137.220 115.331 156.801 1.00 33.80  ? 99  PHE D CD1 1 
ATOM   8955  C CD2 . PHE D 1 99  ? 136.229 115.827 154.698 1.00 33.80  ? 99  PHE D CD2 1 
ATOM   8956  C CE1 . PHE D 1 99  ? 138.434 115.789 156.337 1.00 33.80  ? 99  PHE D CE1 1 
ATOM   8957  C CE2 . PHE D 1 99  ? 137.442 116.282 154.229 1.00 33.80  ? 99  PHE D CE2 1 
ATOM   8958  C CZ  . PHE D 1 99  ? 138.546 116.262 155.050 1.00 33.80  ? 99  PHE D CZ  1 
ATOM   8959  N N   . PHE D 1 100 ? 134.773 112.523 154.263 1.00 32.18  ? 100 PHE D N   1 
ATOM   8960  C CA  . PHE D 1 100 ? 135.408 111.968 153.076 1.00 32.18  ? 100 PHE D CA  1 
ATOM   8961  C C   . PHE D 1 100 ? 136.181 113.069 152.363 1.00 32.18  ? 100 PHE D C   1 
ATOM   8962  O O   . PHE D 1 100 ? 135.611 114.109 152.016 1.00 32.18  ? 100 PHE D O   1 
ATOM   8963  C CB  . PHE D 1 100 ? 134.360 111.344 152.161 1.00 32.18  ? 100 PHE D CB  1 
ATOM   8964  C CG  . PHE D 1 100 ? 133.582 110.241 152.808 1.00 32.18  ? 100 PHE D CG  1 
ATOM   8965  C CD1 . PHE D 1 100 ? 134.039 108.939 152.768 1.00 32.18  ? 100 PHE D CD1 1 
ATOM   8966  C CD2 . PHE D 1 100 ? 132.399 110.507 153.469 1.00 32.18  ? 100 PHE D CD2 1 
ATOM   8967  C CE1 . PHE D 1 100 ? 133.328 107.923 153.367 1.00 32.18  ? 100 PHE D CE1 1 
ATOM   8968  C CE2 . PHE D 1 100 ? 131.685 109.495 154.070 1.00 32.18  ? 100 PHE D CE2 1 
ATOM   8969  C CZ  . PHE D 1 100 ? 132.151 108.202 154.020 1.00 32.18  ? 100 PHE D CZ  1 
ATOM   8970  N N   . ALA D 1 101 ? 137.479 112.845 152.154 1.00 31.56  ? 101 ALA D N   1 
ATOM   8971  C CA  . ALA D 1 101 ? 138.333 113.895 151.610 1.00 31.56  ? 101 ALA D CA  1 
ATOM   8972  C C   . ALA D 1 101 ? 137.923 114.277 150.195 1.00 31.56  ? 101 ALA D C   1 
ATOM   8973  O O   . ALA D 1 101 ? 137.906 115.462 149.847 1.00 31.56  ? 101 ALA D O   1 
ATOM   8974  C CB  . ALA D 1 101 ? 139.795 113.454 151.642 1.00 31.56  ? 101 ALA D CB  1 
ATOM   8975  N N   . ASN D 1 102 ? 137.592 113.294 149.366 1.00 31.22  ? 102 ASN D N   1 
ATOM   8976  C CA  . ASN D 1 102 ? 137.237 113.534 147.970 1.00 31.22  ? 102 ASN D CA  1 
ATOM   8977  C C   . ASN D 1 102 ? 135.758 113.217 147.777 1.00 31.22  ? 102 ASN D C   1 
ATOM   8978  O O   . ASN D 1 102 ? 135.371 112.051 147.663 1.00 31.22  ? 102 ASN D O   1 
ATOM   8979  C CB  . ASN D 1 102 ? 138.114 112.705 147.036 1.00 31.22  ? 102 ASN D CB  1 
ATOM   8980  C CG  . ASN D 1 102 ? 138.123 111.237 147.394 1.00 31.22  ? 102 ASN D CG  1 
ATOM   8981  O OD1 . ASN D 1 102 ? 138.866 110.805 148.270 1.00 31.22  ? 102 ASN D OD1 1 
ATOM   8982  N ND2 . ASN D 1 102 ? 137.290 110.461 146.717 1.00 31.22  ? 102 ASN D ND2 1 
ATOM   8983  N N   . GLU D 1 103 ? 134.933 114.262 147.739 1.00 33.57  ? 103 GLU D N   1 
ATOM   8984  C CA  . GLU D 1 103 ? 133.515 114.109 147.444 1.00 33.57  ? 103 GLU D CA  1 
ATOM   8985  C C   . GLU D 1 103 ? 132.952 115.468 147.067 1.00 33.57  ? 103 GLU D C   1 
ATOM   8986  O O   . GLU D 1 103 ? 133.163 116.448 147.786 1.00 33.57  ? 103 GLU D O   1 
ATOM   8987  C CB  . GLU D 1 103 ? 132.754 113.516 148.634 1.00 33.57  ? 103 GLU D CB  1 
ATOM   8988  C CG  . GLU D 1 103 ? 133.001 114.217 149.950 1.00 33.57  ? 103 GLU D CG  1 
ATOM   8989  C CD  . GLU D 1 103 ? 131.795 115.000 150.418 1.00 33.57  ? 103 GLU D CD  1 
ATOM   8990  O OE1 . GLU D 1 103 ? 130.801 115.061 149.665 1.00 33.57  ? 103 GLU D OE1 1 
ATOM   8991  O OE2 . GLU D 1 103 ? 131.840 115.552 151.537 1.00 33.57  ? 103 GLU D OE2 1 
ATOM   8992  N N   . LYS D 1 104 ? 132.251 115.526 145.935 1.00 34.38  ? 104 LYS D N   1 
ATOM   8993  C CA  . LYS D 1 104 ? 131.688 116.793 145.483 1.00 34.38  ? 104 LYS D CA  1 
ATOM   8994  C C   . LYS D 1 104 ? 130.470 117.192 146.303 1.00 34.38  ? 104 LYS D C   1 
ATOM   8995  O O   . LYS D 1 104 ? 130.209 118.387 146.479 1.00 34.38  ? 104 LYS D O   1 
ATOM   8996  C CB  . LYS D 1 104 ? 131.330 116.708 144.002 1.00 34.38  ? 104 LYS D CB  1 
ATOM   8997  C CG  . LYS D 1 104 ? 132.520 116.867 143.077 1.00 34.38  ? 104 LYS D CG  1 
ATOM   8998  C CD  . LYS D 1 104 ? 132.099 116.833 141.622 1.00 34.38  ? 104 LYS D CD  1 
ATOM   8999  C CE  . LYS D 1 104 ? 133.197 117.379 140.730 1.00 34.38  ? 104 LYS D CE  1 
ATOM   9000  N NZ  . LYS D 1 104 ? 134.496 116.703 140.992 1.00 34.38  ? 104 LYS D NZ  1 
ATOM   9001  N N   . GLY D 1 105 ? 129.715 116.219 146.802 1.00 30.48  ? 105 GLY D N   1 
ATOM   9002  C CA  . GLY D 1 105 ? 128.563 116.507 147.630 1.00 30.48  ? 105 GLY D CA  1 
ATOM   9003  C C   . GLY D 1 105 ? 128.001 115.271 148.297 1.00 30.48  ? 105 GLY D C   1 
ATOM   9004  O O   . GLY D 1 105 ? 127.772 114.254 147.639 1.00 30.48  ? 105 GLY D O   1 
ATOM   9005  N N   . ALA D 1 106 ? 127.773 115.344 149.604 1.00 29.31  ? 106 ALA D N   1 
ATOM   9006  C CA  . ALA D 1 106 ? 127.241 114.222 150.359 1.00 29.31  ? 106 ALA D CA  1 
ATOM   9007  C C   . ALA D 1 106 ? 126.128 114.716 151.267 1.00 29.31  ? 106 ALA D C   1 
ATOM   9008  O O   . ALA D 1 106 ? 126.110 115.881 151.671 1.00 29.31  ? 106 ALA D O   1 
ATOM   9009  C CB  . ALA D 1 106 ? 128.328 113.531 151.185 1.00 29.31  ? 106 ALA D CB  1 
ATOM   9010  N N   . ASN D 1 107 ? 125.199 113.820 151.586 1.00 30.55  ? 107 ASN D N   1 
ATOM   9011  C CA  . ASN D 1 107 ? 124.066 114.178 152.422 1.00 30.55  ? 107 ASN D CA  1 
ATOM   9012  C C   . ASN D 1 107 ? 123.578 112.943 153.159 1.00 30.55  ? 107 ASN D C   1 
ATOM   9013  O O   . ASN D 1 107 ? 123.781 111.812 152.716 1.00 30.55  ? 107 ASN D O   1 
ATOM   9014  C CB  . ASN D 1 107 ? 122.932 114.785 151.594 1.00 30.55  ? 107 ASN D CB  1 
ATOM   9015  C CG  . ASN D 1 107 ? 122.596 113.952 150.381 1.00 30.55  ? 107 ASN D CG  1 
ATOM   9016  O OD1 . ASN D 1 107 ? 123.390 113.116 149.954 1.00 30.55  ? 107 ASN D OD1 1 
ATOM   9017  N ND2 . ASN D 1 107 ? 121.417 114.174 149.814 1.00 30.55  ? 107 ASN D ND2 1 
ATOM   9018  N N   . PHE D 1 108 ? 122.919 113.176 154.289 1.00 33.37  ? 108 PHE D N   1 
ATOM   9019  C CA  . PHE D 1 108 ? 122.362 112.092 155.084 1.00 33.37  ? 108 PHE D CA  1 
ATOM   9020  C C   . PHE D 1 108 ? 121.091 111.577 154.416 1.00 33.37  ? 108 PHE D C   1 
ATOM   9021  O O   . PHE D 1 108 ? 120.732 111.978 153.306 1.00 33.37  ? 108 PHE D O   1 
ATOM   9022  C CB  . PHE D 1 108 ? 122.089 112.560 156.509 1.00 33.37  ? 108 PHE D CB  1 
ATOM   9023  C CG  . PHE D 1 108 ? 123.309 113.027 157.241 1.00 33.37  ? 108 PHE D CG  1 
ATOM   9024  C CD1 . PHE D 1 108 ? 124.131 112.125 157.888 1.00 33.37  ? 108 PHE D CD1 1 
ATOM   9025  C CD2 . PHE D 1 108 ? 123.623 114.371 157.298 1.00 33.37  ? 108 PHE D CD2 1 
ATOM   9026  C CE1 . PHE D 1 108 ? 125.248 112.554 158.568 1.00 33.37  ? 108 PHE D CE1 1 
ATOM   9027  C CE2 . PHE D 1 108 ? 124.740 114.804 157.977 1.00 33.37  ? 108 PHE D CE2 1 
ATOM   9028  C CZ  . PHE D 1 108 ? 125.553 113.895 158.613 1.00 33.37  ? 108 PHE D CZ  1 
ATOM   9029  N N   . HIS D 1 109 ? 120.393 110.670 155.092 1.00 40.00  ? 109 HIS D N   1 
ATOM   9030  C CA  . HIS D 1 109 ? 119.105 110.165 154.635 1.00 40.00  ? 109 HIS D CA  1 
ATOM   9031  C C   . HIS D 1 109 ? 118.137 110.211 155.804 1.00 40.00  ? 109 HIS D C   1 
ATOM   9032  O O   . HIS D 1 109 ? 118.360 109.548 156.822 1.00 40.00  ? 109 HIS D O   1 
ATOM   9033  C CB  . HIS D 1 109 ? 119.230 108.742 154.088 1.00 40.00  ? 109 HIS D CB  1 
ATOM   9034  C CG  . HIS D 1 109 ? 119.681 108.680 152.663 1.00 40.00  ? 109 HIS D CG  1 
ATOM   9035  N ND1 . HIS D 1 109 ? 119.158 109.493 151.681 1.00 40.00  ? 109 HIS D ND1 1 
ATOM   9036  C CD2 . HIS D 1 109 ? 120.607 107.903 152.054 1.00 40.00  ? 109 HIS D CD2 1 
ATOM   9037  C CE1 . HIS D 1 109 ? 119.741 109.218 150.529 1.00 40.00  ? 109 HIS D CE1 1 
ATOM   9038  N NE2 . HIS D 1 109 ? 120.625 108.257 150.727 1.00 40.00  ? 109 HIS D NE2 1 
ATOM   9039  N N   . GLU D 1 110 ? 117.066 110.988 155.659 1.00 38.64  ? 110 GLU D N   1 
ATOM   9040  C CA  . GLU D 1 110 ? 116.078 111.179 156.719 1.00 38.64  ? 110 GLU D CA  1 
ATOM   9041  C C   . GLU D 1 110 ? 114.690 110.917 156.145 1.00 38.64  ? 110 GLU D C   1 
ATOM   9042  O O   . GLU D 1 110 ? 114.130 111.764 155.443 1.00 38.64  ? 110 GLU D O   1 
ATOM   9043  C CB  . GLU D 1 110 ? 116.177 112.582 157.309 1.00 38.64  ? 110 GLU D CB  1 
ATOM   9044  C CG  . GLU D 1 110 ? 116.584 113.644 156.302 1.00 38.64  ? 110 GLU D CG  1 
ATOM   9045  C CD  . GLU D 1 110 ? 116.990 114.948 156.959 1.00 38.64  ? 110 GLU D CD  1 
ATOM   9046  O OE1 . GLU D 1 110 ? 117.103 114.978 158.202 1.00 38.64  ? 110 GLU D OE1 1 
ATOM   9047  O OE2 . GLU D 1 110 ? 117.200 115.942 156.233 1.00 38.64  ? 110 GLU D OE2 1 
ATOM   9048  N N   . VAL D 1 111 ? 114.137 109.742 156.439 1.00 35.97  ? 111 VAL D N   1 
ATOM   9049  C CA  . VAL D 1 111 ? 112.781 109.386 156.036 1.00 35.97  ? 111 VAL D CA  1 
ATOM   9050  C C   . VAL D 1 111 ? 112.114 108.705 157.223 1.00 35.97  ? 111 VAL D C   1 
ATOM   9051  O O   . VAL D 1 111 ? 112.546 107.628 157.647 1.00 35.97  ? 111 VAL D O   1 
ATOM   9052  C CB  . VAL D 1 111 ? 112.748 108.479 154.799 1.00 35.97  ? 111 VAL D CB  1 
ATOM   9053  C CG1 . VAL D 1 111 ? 112.765 109.322 153.544 1.00 35.97  ? 111 VAL D CG1 1 
ATOM   9054  C CG2 . VAL D 1 111 ? 113.930 107.526 154.810 1.00 35.97  ? 111 VAL D CG2 1 
ATOM   9055  N N   . THR D 1 112 ? 111.089 109.352 157.779 1.00 38.89  ? 112 THR D N   1 
ATOM   9056  C CA  . THR D 1 112 ? 110.308 108.888 158.924 1.00 38.89  ? 112 THR D CA  1 
ATOM   9057  C C   . THR D 1 112 ? 111.138 108.878 160.202 1.00 38.89  ? 112 THR D C   1 
ATOM   9058  O O   . THR D 1 112 ? 110.594 108.674 161.293 1.00 38.89  ? 112 THR D O   1 
ATOM   9059  C CB  . THR D 1 112 ? 109.718 107.496 158.671 1.00 38.89  ? 112 THR D CB  1 
ATOM   9060  O OG1 . THR D 1 112 ? 110.771 106.526 158.634 1.00 38.89  ? 112 THR D OG1 1 
ATOM   9061  C CG2 . THR D 1 112 ? 108.959 107.466 157.356 1.00 38.89  ? 112 THR D CG2 1 
ATOM   9062  N N   . THR D 1 113 ? 112.441 109.119 160.077 1.00 41.44  ? 113 THR D N   1 
ATOM   9063  C CA  . THR D 1 113 ? 113.379 109.256 161.185 1.00 41.44  ? 113 THR D CA  1 
ATOM   9064  C C   . THR D 1 113 ? 114.754 109.497 160.578 1.00 41.44  ? 113 THR D C   1 
ATOM   9065  O O   . THR D 1 113 ? 114.937 109.423 159.360 1.00 41.44  ? 113 THR D O   1 
ATOM   9066  C CB  . THR D 1 113 ? 113.419 108.031 162.099 1.00 41.44  ? 113 THR D CB  1 
ATOM   9067  O OG1 . THR D 1 113 ? 114.033 108.384 163.345 1.00 41.44  ? 113 THR D OG1 1 
ATOM   9068  C CG2 . THR D 1 113 ? 114.212 106.917 161.450 1.00 41.44  ? 113 THR D CG2 1 
ATOM   9069  N N   . ASP D 1 114 ? 115.720 109.784 161.444 1.00 44.58  ? 114 ASP D N   1 
ATOM   9070  C CA  . ASP D 1 114 ? 117.116 109.793 161.036 1.00 44.58  ? 114 ASP D CA  1 
ATOM   9071  C C   . ASP D 1 114 ? 117.627 108.359 160.985 1.00 44.58  ? 114 ASP D C   1 
ATOM   9072  O O   . ASP D 1 114 ? 117.343 107.560 161.881 1.00 44.58  ? 114 ASP D O   1 
ATOM   9073  C CB  . ASP D 1 114 ? 117.953 110.629 162.002 1.00 44.58  ? 114 ASP D CB  1 
ATOM   9074  C CG  . ASP D 1 114 ? 117.916 112.108 161.675 1.00 44.58  ? 114 ASP D CG  1 
ATOM   9075  O OD1 . ASP D 1 114 ? 118.218 112.471 160.519 1.00 44.58  ? 114 ASP D OD1 1 
ATOM   9076  O OD2 . ASP D 1 114 ? 117.582 112.908 162.573 1.00 44.58  ? 114 ASP D OD2 1 
ATOM   9077  N N   . ASN D 1 115 ? 118.373 108.031 159.934 1.00 40.05  ? 115 ASN D N   1 
ATOM   9078  C CA  . ASN D 1 115 ? 118.855 106.667 159.728 1.00 40.05  ? 115 ASN D CA  1 
ATOM   9079  C C   . ASN D 1 115 ? 120.159 106.479 160.492 1.00 40.05  ? 115 ASN D C   1 
ATOM   9080  O O   . ASN D 1 115 ? 121.253 106.687 159.967 1.00 40.05  ? 115 ASN D O   1 
ATOM   9081  C CB  . ASN D 1 115 ? 119.027 106.383 158.243 1.00 40.05  ? 115 ASN D CB  1 
ATOM   9082  C CG  . ASN D 1 115 ? 117.714 106.409 157.498 1.00 40.05  ? 115 ASN D CG  1 
ATOM   9083  O OD1 . ASN D 1 115 ? 116.653 106.236 158.092 1.00 40.05  ? 115 ASN D OD1 1 
ATOM   9084  N ND2 . ASN D 1 115 ? 117.776 106.628 156.193 1.00 40.05  ? 115 ASN D ND2 1 
ATOM   9085  N N   . LYS D 1 116 ? 120.036 106.075 161.754 1.00 41.59  ? 116 LYS D N   1 
ATOM   9086  C CA  . LYS D 1 116 ? 121.177 105.814 162.619 1.00 41.59  ? 116 LYS D CA  1 
ATOM   9087  C C   . LYS D 1 116 ? 120.801 104.687 163.570 1.00 41.59  ? 116 LYS D C   1 
ATOM   9088  O O   . LYS D 1 116 ? 119.654 104.238 163.604 1.00 41.59  ? 116 LYS D O   1 
ATOM   9089  C CB  . LYS D 1 116 ? 121.587 107.064 163.402 1.00 41.59  ? 116 LYS D CB  1 
ATOM   9090  C CG  . LYS D 1 116 ? 122.080 108.225 162.558 1.00 41.59  ? 116 LYS D CG  1 
ATOM   9091  C CD  . LYS D 1 116 ? 122.193 109.494 163.384 1.00 41.59  ? 116 LYS D CD  1 
ATOM   9092  C CE  . LYS D 1 116 ? 122.476 110.703 162.509 1.00 41.59  ? 116 LYS D CE  1 
ATOM   9093  N NZ  . LYS D 1 116 ? 122.532 111.957 163.306 1.00 41.59  ? 116 LYS D NZ  1 
ATOM   9094  N N   . LEU D 1 117 ? 121.779 104.226 164.348 1.00 39.14  ? 117 LEU D N   1 
ATOM   9095  C CA  . LEU D 1 117 ? 121.485 103.266 165.405 1.00 39.14  ? 117 LEU D CA  1 
ATOM   9096  C C   . LEU D 1 117 ? 122.544 103.378 166.490 1.00 39.14  ? 117 LEU D C   1 
ATOM   9097  O O   . LEU D 1 117 ? 123.683 103.767 166.224 1.00 39.14  ? 117 LEU D O   1 
ATOM   9098  C CB  . LEU D 1 117 ? 121.413 101.829 164.875 1.00 39.14  ? 117 LEU D CB  1 
ATOM   9099  C CG  . LEU D 1 117 ? 122.629 100.920 165.041 1.00 39.14  ? 117 LEU D CG  1 
ATOM   9100  C CD1 . LEU D 1 117 ? 122.251 99.487  164.730 1.00 39.14  ? 117 LEU D CD1 1 
ATOM   9101  C CD2 . LEU D 1 117 ? 123.761 101.364 164.149 1.00 39.14  ? 117 LEU D CD2 1 
ATOM   9102  N N   . LEU D 1 118 ? 122.155 103.037 167.717 1.00 46.32  ? 118 LEU D N   1 
ATOM   9103  C CA  . LEU D 1 118 ? 123.069 103.052 168.852 1.00 46.32  ? 118 LEU D CA  1 
ATOM   9104  C C   . LEU D 1 118 ? 123.021 101.704 169.556 1.00 46.32  ? 118 LEU D C   1 
ATOM   9105  O O   . LEU D 1 118 ? 121.957 101.275 170.012 1.00 46.32  ? 118 LEU D O   1 
ATOM   9106  C CB  . LEU D 1 118 ? 122.745 104.189 169.824 1.00 46.32  ? 118 LEU D CB  1 
ATOM   9107  C CG  . LEU D 1 118 ? 123.361 104.096 171.222 1.00 46.32  ? 118 LEU D CG  1 
ATOM   9108  C CD1 . LEU D 1 118 ? 124.858 104.216 171.182 1.00 46.32  ? 118 LEU D CD1 1 
ATOM   9109  C CD2 . LEU D 1 118 ? 122.819 105.195 172.085 1.00 46.32  ? 118 LEU D CD2 1 
ATOM   9110  N N   . ARG D 1 119 ? 124.176 101.046 169.638 1.00 42.62  ? 119 ARG D N   1 
ATOM   9111  C CA  . ARG D 1 119 ? 124.336 99.767  170.320 1.00 42.62  ? 119 ARG D CA  1 
ATOM   9112  C C   . ARG D 1 119 ? 125.575 99.857  171.196 1.00 42.62  ? 119 ARG D C   1 
ATOM   9113  O O   . ARG D 1 119 ? 126.683 100.042 170.684 1.00 42.62  ? 119 ARG D O   1 
ATOM   9114  C CB  . ARG D 1 119 ? 124.465 98.618  169.316 1.00 42.62  ? 119 ARG D CB  1 
ATOM   9115  C CG  . ARG D 1 119 ? 124.959 97.316  169.921 1.00 42.62  ? 119 ARG D CG  1 
ATOM   9116  C CD  . ARG D 1 119 ? 125.034 96.198  168.889 1.00 42.62  ? 119 ARG D CD  1 
ATOM   9117  N NE  . ARG D 1 119 ? 123.720 95.673  168.537 1.00 42.62  ? 119 ARG D NE  1 
ATOM   9118  C CZ  . ARG D 1 119 ? 123.118 95.877  167.374 1.00 42.62  ? 119 ARG D CZ  1 
ATOM   9119  N NH1 . ARG D 1 119 ? 123.689 96.586  166.416 1.00 42.62  ? 119 ARG D NH1 1 
ATOM   9120  N NH2 . ARG D 1 119 ? 121.913 95.355  167.167 1.00 42.62  ? 119 ARG D NH2 1 
ATOM   9121  N N   . ILE D 1 120 ? 125.392 99.723  172.506 1.00 43.21  ? 120 ILE D N   1 
ATOM   9122  C CA  . ILE D 1 120 ? 126.462 99.898  173.481 1.00 43.21  ? 120 ILE D CA  1 
ATOM   9123  C C   . ILE D 1 120 ? 126.695 98.576  174.196 1.00 43.21  ? 120 ILE D C   1 
ATOM   9124  O O   . ILE D 1 120 ? 125.749 97.970  174.714 1.00 43.21  ? 120 ILE D O   1 
ATOM   9125  C CB  . ILE D 1 120 ? 126.127 101.007 174.493 1.00 43.21  ? 120 ILE D CB  1 
ATOM   9126  C CG1 . ILE D 1 120 ? 126.304 102.379 173.853 1.00 43.21  ? 120 ILE D CG1 1 
ATOM   9127  C CG2 . ILE D 1 120 ? 126.994 100.880 175.730 1.00 43.21  ? 120 ILE D CG2 1 
ATOM   9128  C CD1 . ILE D 1 120 ? 125.906 103.520 174.752 1.00 43.21  ? 120 ILE D CD1 1 
ATOM   9129  N N   . PHE D 1 121 ? 127.947 98.135  174.229 1.00 46.95  ? 121 PHE D N   1 
ATOM   9130  C CA  . PHE D 1 121 ? 128.314 96.913  174.924 1.00 46.95  ? 121 PHE D CA  1 
ATOM   9131  C C   . PHE D 1 121 ? 128.699 97.212  176.372 1.00 46.95  ? 121 PHE D C   1 
ATOM   9132  O O   . PHE D 1 121 ? 128.845 98.365  176.780 1.00 46.95  ? 121 PHE D O   1 
ATOM   9133  C CB  . PHE D 1 121 ? 129.454 96.207  174.193 1.00 46.95  ? 121 PHE D CB  1 
ATOM   9134  C CG  . PHE D 1 121 ? 129.181 95.974  172.738 1.00 46.95  ? 121 PHE D CG  1 
ATOM   9135  C CD1 . PHE D 1 121 ? 128.326 94.966  172.336 1.00 46.95  ? 121 PHE D CD1 1 
ATOM   9136  C CD2 . PHE D 1 121 ? 129.769 96.768  171.773 1.00 46.95  ? 121 PHE D CD2 1 
ATOM   9137  C CE1 . PHE D 1 121 ? 128.070 94.750  170.998 1.00 46.95  ? 121 PHE D CE1 1 
ATOM   9138  C CE2 . PHE D 1 121 ? 129.518 96.557  170.434 1.00 46.95  ? 121 PHE D CE2 1 
ATOM   9139  C CZ  . PHE D 1 121 ? 128.666 95.548  170.046 1.00 46.95  ? 121 PHE D CZ  1 
ATOM   9140  N N   . LYS D 1 122 ? 128.853 96.142  177.157 1.00 56.08  ? 122 LYS D N   1 
ATOM   9141  C CA  . LYS D 1 122 ? 129.142 96.301  178.579 1.00 56.08  ? 122 LYS D CA  1 
ATOM   9142  C C   . LYS D 1 122 ? 130.501 96.947  178.810 1.00 56.08  ? 122 LYS D C   1 
ATOM   9143  O O   . LYS D 1 122 ? 130.629 97.854  179.640 1.00 56.08  ? 122 LYS D O   1 
ATOM   9144  C CB  . LYS D 1 122 ? 129.078 94.947  179.284 1.00 56.08  ? 122 LYS D CB  1 
ATOM   9145  C CG  . LYS D 1 122 ? 127.699 94.570  179.787 1.00 56.08  ? 122 LYS D CG  1 
ATOM   9146  C CD  . LYS D 1 122 ? 127.753 93.305  180.627 1.00 56.08  ? 122 LYS D CD  1 
ATOM   9147  C CE  . LYS D 1 122 ? 128.737 93.446  181.774 1.00 56.08  ? 122 LYS D CE  1 
ATOM   9148  N NZ  . LYS D 1 122 ? 128.371 94.563  182.684 1.00 56.08  ? 122 LYS D NZ  1 
ATOM   9149  N N   . ASN D 1 123 ? 131.528 96.498  178.088 1.00 54.19  ? 123 ASN D N   1 
ATOM   9150  C CA  . ASN D 1 123 ? 132.876 97.001  178.321 1.00 54.19  ? 123 ASN D CA  1 
ATOM   9151  C C   . ASN D 1 123 ? 133.062 98.447  177.881 1.00 54.19  ? 123 ASN D C   1 
ATOM   9152  O O   . ASN D 1 123 ? 134.081 99.052  178.227 1.00 54.19  ? 123 ASN D O   1 
ATOM   9153  C CB  . ASN D 1 123 ? 133.901 96.085  177.637 1.00 54.19  ? 123 ASN D CB  1 
ATOM   9154  C CG  . ASN D 1 123 ? 133.915 96.222  176.117 1.00 54.19  ? 123 ASN D CG  1 
ATOM   9155  O OD1 . ASN D 1 123 ? 133.215 97.050  175.534 1.00 54.19  ? 123 ASN D OD1 1 
ATOM   9156  N ND2 . ASN D 1 123 ? 134.728 95.397  175.469 1.00 54.19  ? 123 ASN D ND2 1 
ATOM   9157  N N   . GLY D 1 124 ? 132.113 99.009  177.139 1.00 46.85  ? 124 GLY D N   1 
ATOM   9158  C CA  . GLY D 1 124 ? 132.200 100.373 176.664 1.00 46.85  ? 124 GLY D CA  1 
ATOM   9159  C C   . GLY D 1 124 ? 132.359 100.511 175.168 1.00 46.85  ? 124 GLY D C   1 
ATOM   9160  O O   . GLY D 1 124 ? 132.418 101.643 174.675 1.00 46.85  ? 124 GLY D O   1 
ATOM   9161  N N   . ASN D 1 125 ? 132.449 99.407  174.431 1.00 43.30  ? 125 ASN D N   1 
ATOM   9162  C CA  . ASN D 1 125 ? 132.571 99.492  172.983 1.00 43.30  ? 125 ASN D CA  1 
ATOM   9163  C C   . ASN D 1 125 ? 131.299 100.075 172.377 1.00 43.30  ? 125 ASN D C   1 
ATOM   9164  O O   . ASN D 1 125 ? 130.191 99.826  172.857 1.00 43.30  ? 125 ASN D O   1 
ATOM   9165  C CB  . ASN D 1 125 ? 132.866 98.115  172.392 1.00 43.30  ? 125 ASN D CB  1 
ATOM   9166  C CG  . ASN D 1 125 ? 134.277 97.645  172.686 1.00 43.30  ? 125 ASN D CG  1 
ATOM   9167  O OD1 . ASN D 1 125 ? 134.492 96.495  173.067 1.00 43.30  ? 125 ASN D OD1 1 
ATOM   9168  N ND2 . ASN D 1 125 ? 135.244 98.539  172.528 1.00 43.30  ? 125 ASN D ND2 1 
ATOM   9169  N N   . VAL D 1 126 ? 131.470 100.861 171.317 1.00 41.89  ? 126 VAL D N   1 
ATOM   9170  C CA  . VAL D 1 126 ? 130.400 101.641 170.704 1.00 41.89  ? 126 VAL D CA  1 
ATOM   9171  C C   . VAL D 1 126 ? 130.474 101.404 169.200 1.00 41.89  ? 126 VAL D C   1 
ATOM   9172  O O   . VAL D 1 126 ? 131.520 101.648 168.593 1.00 41.89  ? 126 VAL D O   1 
ATOM   9173  C CB  . VAL D 1 126 ? 130.554 103.140 171.029 1.00 41.89  ? 126 VAL D CB  1 
ATOM   9174  C CG1 . VAL D 1 126 ? 129.301 103.906 170.754 1.00 41.89  ? 126 VAL D CG1 1 
ATOM   9175  C CG2 . VAL D 1 126 ? 130.956 103.335 172.475 1.00 41.89  ? 126 VAL D CG2 1 
ATOM   9176  N N   . LEU D 1 127 ? 129.380 100.932 168.590 1.00 36.12  ? 127 LEU D N   1 
ATOM   9177  C CA  . LEU D 1 127 ? 129.390 100.521 167.180 1.00 36.12  ? 127 LEU D CA  1 
ATOM   9178  C C   . LEU D 1 127 ? 128.447 101.431 166.398 1.00 36.12  ? 127 LEU D C   1 
ATOM   9179  O O   . LEU D 1 127 ? 127.266 101.124 166.230 1.00 36.12  ? 127 LEU D O   1 
ATOM   9180  C CB  . LEU D 1 127 ? 129.010 99.044  167.045 1.00 36.12  ? 127 LEU D CB  1 
ATOM   9181  C CG  . LEU D 1 127 ? 128.786 98.369  165.682 1.00 36.12  ? 127 LEU D CG  1 
ATOM   9182  C CD1 . LEU D 1 127 ? 129.300 96.943  165.743 1.00 36.12  ? 127 LEU D CD1 1 
ATOM   9183  C CD2 . LEU D 1 127 ? 127.331 98.339  165.255 1.00 36.12  ? 127 LEU D CD2 1 
ATOM   9184  N N   . TYR D 1 128 ? 128.976 102.539 165.893 1.00 41.08  ? 128 TYR D N   1 
ATOM   9185  C CA  . TYR D 1 128 ? 128.171 103.612 165.322 1.00 41.08  ? 128 TYR D CA  1 
ATOM   9186  C C   . TYR D 1 128 ? 128.121 103.469 163.809 1.00 41.08  ? 128 TYR D C   1 
ATOM   9187  O O   . TYR D 1 128 ? 129.161 103.513 163.144 1.00 41.08  ? 128 TYR D O   1 
ATOM   9188  C CB  . TYR D 1 128 ? 128.744 104.970 165.723 1.00 41.08  ? 128 TYR D CB  1 
ATOM   9189  C CG  . TYR D 1 128 ? 128.192 106.148 164.964 1.00 41.08  ? 128 TYR D CG  1 
ATOM   9190  C CD1 . TYR D 1 128 ? 126.849 106.474 165.028 1.00 41.08  ? 128 TYR D CD1 1 
ATOM   9191  C CD2 . TYR D 1 128 ? 129.024 106.953 164.203 1.00 41.08  ? 128 TYR D CD2 1 
ATOM   9192  C CE1 . TYR D 1 128 ? 126.349 107.559 164.343 1.00 41.08  ? 128 TYR D CE1 1 
ATOM   9193  C CE2 . TYR D 1 128 ? 128.533 108.039 163.515 1.00 41.08  ? 128 TYR D CE2 1 
ATOM   9194  C CZ  . TYR D 1 128 ? 127.194 108.338 163.589 1.00 41.08  ? 128 TYR D CZ  1 
ATOM   9195  O OH  . TYR D 1 128 ? 126.701 109.421 162.905 1.00 41.08  ? 128 TYR D OH  1 
ATOM   9196  N N   . SER D 1 129 ? 126.916 103.302 163.270 1.00 35.72  ? 129 SER D N   1 
ATOM   9197  C CA  . SER D 1 129 ? 126.712 103.187 161.836 1.00 35.72  ? 129 SER D CA  1 
ATOM   9198  C C   . SER D 1 129 ? 125.752 104.269 161.367 1.00 35.72  ? 129 SER D C   1 
ATOM   9199  O O   . SER D 1 129 ? 124.942 104.787 162.138 1.00 35.72  ? 129 SER D O   1 
ATOM   9200  C CB  . SER D 1 129 ? 126.158 101.816 161.448 1.00 35.72  ? 129 SER D CB  1 
ATOM   9201  O OG  . SER D 1 129 ? 124.755 101.882 161.276 1.00 35.72  ? 129 SER D OG  1 
ATOM   9202  N N   . ILE D 1 130 ? 125.843 104.596 160.079 1.00 40.51  ? 130 ILE D N   1 
ATOM   9203  C CA  . ILE D 1 130 ? 125.046 105.669 159.502 1.00 40.51  ? 130 ILE D CA  1 
ATOM   9204  C C   . ILE D 1 130 ? 124.907 105.399 158.014 1.00 40.51  ? 130 ILE D C   1 
ATOM   9205  O O   . ILE D 1 130 ? 125.744 104.722 157.411 1.00 40.51  ? 130 ILE D O   1 
ATOM   9206  C CB  . ILE D 1 130 ? 125.687 107.051 159.785 1.00 40.51  ? 130 ILE D CB  1 
ATOM   9207  C CG1 . ILE D 1 130 ? 124.681 108.173 159.541 1.00 40.51  ? 130 ILE D CG1 1 
ATOM   9208  C CG2 . ILE D 1 130 ? 126.927 107.252 158.941 1.00 40.51  ? 130 ILE D CG2 1 
ATOM   9209  C CD1 . ILE D 1 130 ? 125.068 109.477 160.180 1.00 40.51  ? 130 ILE D CD1 1 
ATOM   9210  N N   . ARG D 1 131 ? 123.836 105.918 157.422 1.00 47.29  ? 131 ARG D N   1 
ATOM   9211  C CA  . ARG D 1 131 ? 123.568 105.757 156.001 1.00 47.29  ? 131 ARG D CA  1 
ATOM   9212  C C   . ARG D 1 131 ? 123.892 107.057 155.280 1.00 47.29  ? 131 ARG D C   1 
ATOM   9213  O O   . ARG D 1 131 ? 123.435 108.127 155.690 1.00 47.29  ? 131 ARG D O   1 
ATOM   9214  C CB  . ARG D 1 131 ? 122.111 105.371 155.763 1.00 47.29  ? 131 ARG D CB  1 
ATOM   9215  C CG  . ARG D 1 131 ? 121.783 105.088 154.315 1.00 47.29  ? 131 ARG D CG  1 
ATOM   9216  C CD  . ARG D 1 131 ? 120.443 104.392 154.183 1.00 47.29  ? 131 ARG D CD  1 
ATOM   9217  N NE  . ARG D 1 131 ? 120.263 103.831 152.852 1.00 47.29  ? 131 ARG D NE  1 
ATOM   9218  C CZ  . ARG D 1 131 ? 119.483 104.354 151.918 1.00 47.29  ? 131 ARG D CZ  1 
ATOM   9219  N NH1 . ARG D 1 131 ? 118.767 105.442 152.147 1.00 47.29  ? 131 ARG D NH1 1 
ATOM   9220  N NH2 . ARG D 1 131 ? 119.418 103.770 150.726 1.00 47.29  ? 131 ARG D NH2 1 
ATOM   9221  N N   . LEU D 1 132 ? 124.677 106.962 154.211 1.00 47.29  ? 132 LEU D N   1 
ATOM   9222  C CA  . LEU D 1 132 ? 125.154 108.132 153.492 1.00 47.29  ? 132 LEU D CA  1 
ATOM   9223  C C   . LEU D 1 132 ? 125.016 107.922 151.993 1.00 47.29  ? 132 LEU D C   1 
ATOM   9224  O O   . LEU D 1 132 ? 124.958 106.790 151.509 1.00 47.29  ? 132 LEU D O   1 
ATOM   9225  C CB  . LEU D 1 132 ? 126.615 108.433 153.830 1.00 47.29  ? 132 LEU D CB  1 
ATOM   9226  C CG  . LEU D 1 132 ? 126.919 108.805 155.278 1.00 47.29  ? 132 LEU D CG  1 
ATOM   9227  C CD1 . LEU D 1 132 ? 128.410 108.984 155.477 1.00 47.29  ? 132 LEU D CD1 1 
ATOM   9228  C CD2 . LEU D 1 132 ? 126.177 110.067 155.655 1.00 47.29  ? 132 LEU D CD2 1 
ATOM   9229  N N   . THR D 1 133 ? 124.961 109.033 151.262 1.00 32.45  ? 133 THR D N   1 
ATOM   9230  C CA  . THR D 1 133 ? 124.951 109.028 149.803 1.00 32.45  ? 133 THR D CA  1 
ATOM   9231  C C   . THR D 1 133 ? 126.030 109.992 149.334 1.00 32.45  ? 133 THR D C   1 
ATOM   9232  O O   . THR D 1 133 ? 125.878 111.209 149.469 1.00 32.45  ? 133 THR D O   1 
ATOM   9233  C CB  . THR D 1 133 ? 123.584 109.429 149.251 1.00 32.45  ? 133 THR D CB  1 
ATOM   9234  O OG1 . THR D 1 133 ? 122.629 108.402 149.544 1.00 32.45  ? 133 THR D OG1 1 
ATOM   9235  C CG2 . THR D 1 133 ? 123.654 109.630 147.747 1.00 32.45  ? 133 THR D CG2 1 
ATOM   9236  N N   . LEU D 1 134 ? 127.113 109.456 148.787 1.00 30.36  ? 134 LEU D N   1 
ATOM   9237  C CA  . LEU D 1 134 ? 128.284 110.245 148.434 1.00 30.36  ? 134 LEU D CA  1 
ATOM   9238  C C   . LEU D 1 134 ? 128.440 110.303 146.923 1.00 30.36  ? 134 LEU D C   1 
ATOM   9239  O O   . LEU D 1 134 ? 128.355 109.274 146.247 1.00 30.36  ? 134 LEU D O   1 
ATOM   9240  C CB  . LEU D 1 134 ? 129.545 109.652 149.058 1.00 30.36  ? 134 LEU D CB  1 
ATOM   9241  C CG  . LEU D 1 134 ? 129.383 108.969 150.410 1.00 30.36  ? 134 LEU D CG  1 
ATOM   9242  C CD1 . LEU D 1 134 ? 130.676 108.288 150.794 1.00 30.36  ? 134 LEU D CD1 1 
ATOM   9243  C CD2 . LEU D 1 134 ? 128.983 109.975 151.464 1.00 30.36  ? 134 LEU D CD2 1 
ATOM   9244  N N   . THR D 1 135 ? 128.667 111.501 146.399 1.00 29.15  ? 135 THR D N   1 
ATOM   9245  C CA  . THR D 1 135 ? 129.047 111.674 144.998 1.00 29.15  ? 135 THR D CA  1 
ATOM   9246  C C   . THR D 1 135 ? 130.562 111.812 144.883 1.00 29.15  ? 135 THR D C   1 
ATOM   9247  O O   . THR D 1 135 ? 131.095 112.847 144.491 1.00 29.15  ? 135 THR D O   1 
ATOM   9248  C CB  . THR D 1 135 ? 128.340 112.883 144.398 1.00 29.15  ? 135 THR D CB  1 
ATOM   9249  O OG1 . THR D 1 135 ? 129.001 114.080 144.823 1.00 29.15  ? 135 THR D OG1 1 
ATOM   9250  C CG2 . THR D 1 135 ? 126.895 112.928 144.847 1.00 29.15  ? 135 THR D CG2 1 
ATOM   9251  N N   . LEU D 1 136 ? 131.252 110.735 145.248 1.00 31.63  ? 136 LEU D N   1 
ATOM   9252  C CA  . LEU D 1 136 ? 132.707 110.737 145.230 1.00 31.63  ? 136 LEU D CA  1 
ATOM   9253  C C   . LEU D 1 136 ? 133.225 110.977 143.821 1.00 31.63  ? 136 LEU D C   1 
ATOM   9254  O O   . LEU D 1 136 ? 132.633 110.527 142.837 1.00 31.63  ? 136 LEU D O   1 
ATOM   9255  C CB  . LEU D 1 136 ? 133.240 109.409 145.759 1.00 31.63  ? 136 LEU D CB  1 
ATOM   9256  C CG  . LEU D 1 136 ? 132.615 108.926 147.062 1.00 31.63  ? 136 LEU D CG  1 
ATOM   9257  C CD1 . LEU D 1 136 ? 132.948 107.471 147.288 1.00 31.63  ? 136 LEU D CD1 1 
ATOM   9258  C CD2 . LEU D 1 136 ? 133.108 109.769 148.217 1.00 31.63  ? 136 LEU D CD2 1 
ATOM   9259  N N   . SER D 1 137 ? 134.336 111.698 143.725 1.00 32.09  ? 137 SER D N   1 
ATOM   9260  C CA  . SER D 1 137 ? 134.982 111.980 142.453 1.00 32.09  ? 137 SER D CA  1 
ATOM   9261  C C   . SER D 1 137 ? 136.299 111.224 142.385 1.00 32.09  ? 137 SER D C   1 
ATOM   9262  O O   . SER D 1 137 ? 137.137 111.347 143.283 1.00 32.09  ? 137 SER D O   1 
ATOM   9263  C CB  . SER D 1 137 ? 135.222 113.479 142.278 1.00 32.09  ? 137 SER D CB  1 
ATOM   9264  O OG  . SER D 1 137 ? 133.997 114.179 142.160 1.00 32.09  ? 137 SER D OG  1 
ATOM   9265  N N   . CYS D 1 138 ? 136.473 110.443 141.324 1.00 38.21  ? 138 CYS D N   1 
ATOM   9266  C CA  . CYS D 1 138 ? 137.706 109.722 141.090 1.00 38.21  ? 138 CYS D CA  1 
ATOM   9267  C C   . CYS D 1 138 ? 138.295 110.149 139.754 1.00 38.21  ? 138 CYS D C   1 
ATOM   9268  O O   . CYS D 1 138 ? 137.600 110.084 138.730 1.00 38.21  ? 138 CYS D O   1 
ATOM   9269  C CB  . CYS D 1 138 ? 137.475 108.206 141.095 1.00 38.21  ? 138 CYS D CB  1 
ATOM   9270  S SG  . CYS D 1 138 ? 136.096 107.618 140.086 1.00 38.21  ? 138 CYS D SG  1 
ATOM   9271  N N   . PRO D 1 139 ? 139.547 110.601 139.718 1.00 41.59  ? 139 PRO D N   1 
ATOM   9272  C CA  . PRO D 1 139 ? 140.150 110.985 138.438 1.00 41.59  ? 139 PRO D CA  1 
ATOM   9273  C C   . PRO D 1 139 ? 140.163 109.808 137.477 1.00 41.59  ? 139 PRO D C   1 
ATOM   9274  O O   . PRO D 1 139 ? 140.452 108.672 137.859 1.00 41.59  ? 139 PRO D O   1 
ATOM   9275  C CB  . PRO D 1 139 ? 141.567 111.416 138.828 1.00 41.59  ? 139 PRO D CB  1 
ATOM   9276  C CG  . PRO D 1 139 ? 141.822 110.740 140.137 1.00 41.59  ? 139 PRO D CG  1 
ATOM   9277  C CD  . PRO D 1 139 ? 140.500 110.709 140.834 1.00 41.59  ? 139 PRO D CD  1 
ATOM   9278  N N   . MET D 1 140 ? 139.817 110.050 136.208 1.00 52.37  ? 140 MET D N   1 
ATOM   9279  C CA  . MET D 1 140 ? 139.651 108.905 135.269 1.00 52.37  ? 140 MET D CA  1 
ATOM   9280  C C   . MET D 1 140 ? 140.458 109.091 133.982 1.00 52.37  ? 140 MET D C   1 
ATOM   9281  O O   . MET D 1 140 ? 140.044 109.924 133.160 1.00 52.37  ? 140 MET D O   1 
ATOM   9282  C CB  . MET D 1 140 ? 138.169 108.784 134.904 1.00 52.37  ? 140 MET D CB  1 
ATOM   9283  C CG  . MET D 1 140 ? 137.825 107.576 134.069 1.00 52.37  ? 140 MET D CG  1 
ATOM   9284  S SD  . MET D 1 140 ? 136.115 107.054 134.353 1.00 52.37  ? 140 MET D SD  1 
ATOM   9285  C CE  . MET D 1 140 ? 135.854 107.670 136.015 1.00 52.37  ? 140 MET D CE  1 
ATOM   9286  N N   . ASP D 1 141 ? 141.557 108.350 133.810 1.00 58.28  ? 141 ASP D N   1 
ATOM   9287  C CA  . ASP D 1 141 ? 142.360 108.391 132.555 1.00 58.28  ? 141 ASP D CA  1 
ATOM   9288  C C   . ASP D 1 141 ? 141.601 107.694 131.426 1.00 58.28  ? 141 ASP D C   1 
ATOM   9289  O O   . ASP D 1 141 ? 140.769 106.829 131.736 1.00 58.28  ? 141 ASP D O   1 
ATOM   9290  C CB  . ASP D 1 141 ? 143.716 107.714 132.728 1.00 58.28  ? 141 ASP D CB  1 
ATOM   9291  C CG  . ASP D 1 141 ? 143.778 106.356 132.053 1.00 58.28  ? 141 ASP D CG  1 
ATOM   9292  O OD1 . ASP D 1 141 ? 144.147 106.311 130.863 1.00 58.28  ? 141 ASP D OD1 1 
ATOM   9293  O OD2 . ASP D 1 141 ? 143.442 105.356 132.716 1.00 58.28  ? 141 ASP D OD2 1 
ATOM   9294  N N   . LEU D 1 142 ? 141.867 108.057 130.170 1.00 64.71  ? 142 LEU D N   1 
ATOM   9295  C CA  . LEU D 1 142 ? 141.218 107.321 129.051 1.00 64.71  ? 142 LEU D CA  1 
ATOM   9296  C C   . LEU D 1 142 ? 142.217 107.017 127.923 1.00 64.71  ? 142 LEU D C   1 
ATOM   9297  O O   . LEU D 1 142 ? 141.772 106.927 126.766 1.00 64.71  ? 142 LEU D O   1 
ATOM   9298  C CB  . LEU D 1 142 ? 140.023 108.144 128.564 1.00 64.71  ? 142 LEU D CB  1 
ATOM   9299  C CG  . LEU D 1 142 ? 138.769 108.026 129.429 1.00 64.71  ? 142 LEU D CG  1 
ATOM   9300  C CD1 . LEU D 1 142 ? 137.676 108.962 128.940 1.00 64.71  ? 142 LEU D CD1 1 
ATOM   9301  C CD2 . LEU D 1 142 ? 138.270 106.590 129.461 1.00 64.71  ? 142 LEU D CD2 1 
ATOM   9302  N N   . LYS D 1 143 ? 143.504 106.838 128.240 1.00 69.02  ? 143 LYS D N   1 
ATOM   9303  C CA  . LYS D 1 143 ? 144.507 106.467 127.249 1.00 69.02  ? 143 LYS D CA  1 
ATOM   9304  C C   . LYS D 1 143 ? 143.935 105.470 126.251 1.00 69.02  ? 143 LYS D C   1 
ATOM   9305  O O   . LYS D 1 143 ? 144.170 105.582 125.043 1.00 69.02  ? 143 LYS D O   1 
ATOM   9306  C CB  . LYS D 1 143 ? 145.743 105.894 127.939 1.00 69.02  ? 143 LYS D CB  1 
ATOM   9307  N N   . ASN D 1 144 ? 143.173 104.493 126.740 1.00 67.42  ? 144 ASN D N   1 
ATOM   9308  C CA  . ASN D 1 144 ? 142.435 103.548 125.902 1.00 67.42  ? 144 ASN D CA  1 
ATOM   9309  C C   . ASN D 1 144 ? 140.997 103.558 126.410 1.00 67.42  ? 144 ASN D C   1 
ATOM   9310  O O   . ASN D 1 144 ? 140.638 102.772 127.290 1.00 67.42  ? 144 ASN D O   1 
ATOM   9311  C CB  . ASN D 1 144 ? 143.053 102.160 125.957 1.00 67.42  ? 144 ASN D CB  1 
ATOM   9312  C CG  . ASN D 1 144 ? 143.524 101.791 127.344 1.00 67.42  ? 144 ASN D CG  1 
ATOM   9313  O OD1 . ASN D 1 144 ? 144.044 102.630 128.078 1.00 67.42  ? 144 ASN D OD1 1 
ATOM   9314  N ND2 . ASN D 1 144 ? 143.340 100.532 127.715 1.00 67.42  ? 144 ASN D ND2 1 
ATOM   9315  N N   . PHE D 1 145 ? 140.181 104.450 125.846 1.00 65.25  ? 145 PHE D N   1 
ATOM   9316  C CA  . PHE D 1 145 ? 138.854 104.711 126.401 1.00 65.25  ? 145 PHE D CA  1 
ATOM   9317  C C   . PHE D 1 145 ? 137.956 103.481 126.460 1.00 65.25  ? 145 PHE D C   1 
ATOM   9318  O O   . PHE D 1 145 ? 137.366 103.233 127.526 1.00 65.25  ? 145 PHE D O   1 
ATOM   9319  C CB  . PHE D 1 145 ? 138.186 105.842 125.613 1.00 65.25  ? 145 PHE D CB  1 
ATOM   9320  C CG  . PHE D 1 145 ? 136.689 105.768 125.604 1.00 65.25  ? 145 PHE D CG  1 
ATOM   9321  C CD1 . PHE D 1 145 ? 135.959 106.143 126.716 1.00 65.25  ? 145 PHE D CD1 1 
ATOM   9322  C CD2 . PHE D 1 145 ? 136.011 105.327 124.483 1.00 65.25  ? 145 PHE D CD2 1 
ATOM   9323  C CE1 . PHE D 1 145 ? 134.581 106.078 126.710 1.00 65.25  ? 145 PHE D CE1 1 
ATOM   9324  C CE2 . PHE D 1 145 ? 134.632 105.258 124.472 1.00 65.25  ? 145 PHE D CE2 1 
ATOM   9325  C CZ  . PHE D 1 145 ? 133.917 105.635 125.587 1.00 65.25  ? 145 PHE D CZ  1 
ATOM   9326  N N   . PRO D 1 146 ? 137.791 102.683 125.399 1.00 67.24  ? 146 PRO D N   1 
ATOM   9327  C CA  . PRO D 1 146 ? 136.859 101.550 125.485 1.00 67.24  ? 146 PRO D CA  1 
ATOM   9328  C C   . PRO D 1 146 ? 137.408 100.343 126.223 1.00 67.24  ? 146 PRO D C   1 
ATOM   9329  O O   . PRO D 1 146 ? 136.634 99.427  126.531 1.00 67.24  ? 146 PRO D O   1 
ATOM   9330  C CB  . PRO D 1 146 ? 136.583 101.206 124.010 1.00 67.24  ? 146 PRO D CB  1 
ATOM   9331  C CG  . PRO D 1 146 ? 137.269 102.269 123.202 1.00 67.24  ? 146 PRO D CG  1 
ATOM   9332  C CD  . PRO D 1 146 ? 138.371 102.778 124.052 1.00 67.24  ? 146 PRO D CD  1 
ATOM   9333  N N   . MET D 1 147 ? 138.704 100.303 126.514 1.00 69.53  ? 147 MET D N   1 
ATOM   9334  C CA  . MET D 1 147 ? 139.346 99.154  127.145 1.00 69.53  ? 147 MET D CA  1 
ATOM   9335  C C   . MET D 1 147 ? 140.160 99.598  128.353 1.00 69.53  ? 147 MET D C   1 
ATOM   9336  O O   . MET D 1 147 ? 141.325 99.232  128.521 1.00 69.53  ? 147 MET D O   1 
ATOM   9337  C CB  . MET D 1 147 ? 140.223 98.408  126.142 1.00 69.53  ? 147 MET D CB  1 
ATOM   9338  C CG  . MET D 1 147 ? 139.645 98.345  124.735 1.00 69.53  ? 147 MET D CG  1 
ATOM   9339  S SD  . MET D 1 147 ? 140.907 98.305  123.450 1.00 69.53  ? 147 MET D SD  1 
ATOM   9340  C CE  . MET D 1 147 ? 141.381 96.581  123.500 1.00 69.53  ? 147 MET D CE  1 
ATOM   9341  N N   . ASP D 1 148 ? 139.548 100.404 129.215 1.00 57.69  ? 148 ASP D N   1 
ATOM   9342  C CA  . ASP D 1 148 ? 140.236 101.000 130.351 1.00 57.69  ? 148 ASP D CA  1 
ATOM   9343  C C   . ASP D 1 148 ? 139.822 100.329 131.653 1.00 57.69  ? 148 ASP D C   1 
ATOM   9344  O O   . ASP D 1 148 ? 138.654 99.980  131.843 1.00 57.69  ? 148 ASP D O   1 
ATOM   9345  C CB  . ASP D 1 148 ? 139.948 102.500 130.433 1.00 57.69  ? 148 ASP D CB  1 
ATOM   9346  C CG  . ASP D 1 148 ? 138.475 102.802 130.614 1.00 57.69  ? 148 ASP D CG  1 
ATOM   9347  O OD1 . ASP D 1 148 ? 137.641 102.006 130.136 1.00 57.69  ? 148 ASP D OD1 1 
ATOM   9348  O OD2 . ASP D 1 148 ? 138.151 103.837 131.231 1.00 57.69  ? 148 ASP D OD2 1 
ATOM   9349  N N   . VAL D 1 149 ? 140.790 100.153 132.546 1.00 53.42  ? 149 VAL D N   1 
ATOM   9350  C CA  . VAL D 1 149 ? 140.549 99.668  133.899 1.00 53.42  ? 149 VAL D CA  1 
ATOM   9351  C C   . VAL D 1 149 ? 140.712 100.852 134.839 1.00 53.42  ? 149 VAL D C   1 
ATOM   9352  O O   . VAL D 1 149 ? 141.818 101.385 134.990 1.00 53.42  ? 149 VAL D O   1 
ATOM   9353  C CB  . VAL D 1 149 ? 141.507 98.529  134.274 1.00 53.42  ? 149 VAL D CB  1 
ATOM   9354  C CG1 . VAL D 1 149 ? 141.431 98.242  135.763 1.00 53.42  ? 149 VAL D CG1 1 
ATOM   9355  C CG2 . VAL D 1 149 ? 141.185 97.283  133.468 1.00 53.42  ? 149 VAL D CG2 1 
ATOM   9356  N N   . GLN D 1 150 ? 139.617 101.263 135.470 1.00 49.08  ? 150 GLN D N   1 
ATOM   9357  C CA  . GLN D 1 150 ? 139.593 102.467 136.288 1.00 49.08  ? 150 GLN D CA  1 
ATOM   9358  C C   . GLN D 1 150 ? 139.732 102.116 137.761 1.00 49.08  ? 150 GLN D C   1 
ATOM   9359  O O   . GLN D 1 150 ? 139.223 101.089 138.218 1.00 49.08  ? 150 GLN D O   1 
ATOM   9360  C CB  . GLN D 1 150 ? 138.298 103.248 136.066 1.00 49.08  ? 150 GLN D CB  1 
ATOM   9361  C CG  . GLN D 1 150 ? 138.122 103.755 134.653 1.00 49.08  ? 150 GLN D CG  1 
ATOM   9362  C CD  . GLN D 1 150 ? 139.223 104.703 134.234 1.00 49.08  ? 150 GLN D CD  1 
ATOM   9363  O OE1 . GLN D 1 150 ? 139.853 105.352 135.069 1.00 49.08  ? 150 GLN D OE1 1 
ATOM   9364  N NE2 . GLN D 1 150 ? 139.460 104.792 132.932 1.00 49.08  ? 150 GLN D NE2 1 
ATOM   9365  N N   . THR D 1 151 ? 140.426 102.977 138.501 1.00 41.05  ? 151 THR D N   1 
ATOM   9366  C CA  . THR D 1 151 ? 140.587 102.831 139.944 1.00 41.05  ? 151 THR D CA  1 
ATOM   9367  C C   . THR D 1 151 ? 139.982 104.056 140.613 1.00 41.05  ? 151 THR D C   1 
ATOM   9368  O O   . THR D 1 151 ? 140.552 105.150 140.544 1.00 41.05  ? 151 THR D O   1 
ATOM   9369  C CB  . THR D 1 151 ? 142.057 102.674 140.329 1.00 41.05  ? 151 THR D CB  1 
ATOM   9370  O OG1 . THR D 1 151 ? 142.768 103.876 140.009 1.00 41.05  ? 151 THR D OG1 1 
ATOM   9371  C CG2 . THR D 1 151 ? 142.683 101.509 139.584 1.00 41.05  ? 151 THR D CG2 1 
ATOM   9372  N N   . CYS D 1 152 ? 138.837 103.875 141.260 1.00 36.61  ? 152 CYS D N   1 
ATOM   9373  C CA  . CYS D 1 152 ? 138.181 104.944 141.994 1.00 36.61  ? 152 CYS D CA  1 
ATOM   9374  C C   . CYS D 1 152 ? 138.358 104.718 143.489 1.00 36.61  ? 152 CYS D C   1 
ATOM   9375  O O   . CYS D 1 152 ? 138.399 103.578 143.960 1.00 36.61  ? 152 CYS D O   1 
ATOM   9376  C CB  . CYS D 1 152 ? 136.696 105.036 141.633 1.00 36.61  ? 152 CYS D CB  1 
ATOM   9377  S SG  . CYS D 1 152 ? 136.385 105.609 139.938 1.00 36.61  ? 152 CYS D SG  1 
ATOM   9378  N N   . ILE D 1 153 ? 138.467 105.816 144.232 1.00 31.42  ? 153 ILE D N   1 
ATOM   9379  C CA  . ILE D 1 153 ? 138.956 105.778 145.603 1.00 31.42  ? 153 ILE D CA  1 
ATOM   9380  C C   . ILE D 1 153 ? 137.969 106.464 146.534 1.00 31.42  ? 153 ILE D C   1 
ATOM   9381  O O   . ILE D 1 153 ? 137.184 107.323 146.121 1.00 31.42  ? 153 ILE D O   1 
ATOM   9382  C CB  . ILE D 1 153 ? 140.343 106.442 145.711 1.00 31.42  ? 153 ILE D CB  1 
ATOM   9383  C CG1 . ILE D 1 153 ? 140.268 107.893 145.240 1.00 31.42  ? 153 ILE D CG1 1 
ATOM   9384  C CG2 . ILE D 1 153 ? 141.355 105.689 144.880 1.00 31.42  ? 153 ILE D CG2 1 
ATOM   9385  C CD1 . ILE D 1 153 ? 141.619 108.540 145.039 1.00 31.42  ? 153 ILE D CD1 1 
ATOM   9386  N N   . MET D 1 154 ? 138.014 106.069 147.806 1.00 34.27  ? 154 MET D N   1 
ATOM   9387  C CA  . MET D 1 154 ? 137.305 106.746 148.883 1.00 34.27  ? 154 MET D CA  1 
ATOM   9388  C C   . MET D 1 154 ? 138.289 106.993 150.013 1.00 34.27  ? 154 MET D C   1 
ATOM   9389  O O   . MET D 1 154 ? 138.946 106.056 150.477 1.00 34.27  ? 154 MET D O   1 
ATOM   9390  C CB  . MET D 1 154 ? 136.127 105.919 149.400 1.00 34.27  ? 154 MET D CB  1 
ATOM   9391  C CG  . MET D 1 154 ? 135.405 105.113 148.345 1.00 34.27  ? 154 MET D CG  1 
ATOM   9392  S SD  . MET D 1 154 ? 134.164 104.026 149.068 1.00 34.27  ? 154 MET D SD  1 
ATOM   9393  C CE  . MET D 1 154 ? 133.923 104.800 150.663 1.00 34.27  ? 154 MET D CE  1 
ATOM   9394  N N   . GLN D 1 155 ? 138.388 108.238 150.463 1.00 31.17  ? 155 GLN D N   1 
ATOM   9395  C CA  . GLN D 1 155 ? 139.355 108.617 151.490 1.00 31.17  ? 155 GLN D CA  1 
ATOM   9396  C C   . GLN D 1 155 ? 138.605 109.078 152.734 1.00 31.17  ? 155 GLN D C   1 
ATOM   9397  O O   . GLN D 1 155 ? 138.146 110.222 152.801 1.00 31.17  ? 155 GLN D O   1 
ATOM   9398  C CB  . GLN D 1 155 ? 140.296 109.701 150.980 1.00 31.17  ? 155 GLN D CB  1 
ATOM   9399  C CG  . GLN D 1 155 ? 141.247 109.235 149.896 1.00 31.17  ? 155 GLN D CG  1 
ATOM   9400  C CD  . GLN D 1 155 ? 142.283 110.281 149.545 1.00 31.17  ? 155 GLN D CD  1 
ATOM   9401  O OE1 . GLN D 1 155 ? 142.406 110.686 148.390 1.00 31.17  ? 155 GLN D OE1 1 
ATOM   9402  N NE2 . GLN D 1 155 ? 143.037 110.723 150.542 1.00 31.17  ? 155 GLN D NE2 1 
ATOM   9403  N N   . LEU D 1 156 ? 138.490 108.193 153.718 1.00 30.23  ? 156 LEU D N   1 
ATOM   9404  C CA  . LEU D 1 156 ? 137.948 108.552 155.020 1.00 30.23  ? 156 LEU D CA  1 
ATOM   9405  C C   . LEU D 1 156 ? 139.068 109.113 155.881 1.00 30.23  ? 156 LEU D C   1 
ATOM   9406  O O   . LEU D 1 156 ? 140.129 108.494 156.006 1.00 30.23  ? 156 LEU D O   1 
ATOM   9407  C CB  . LEU D 1 156 ? 137.318 107.341 155.706 1.00 30.23  ? 156 LEU D CB  1 
ATOM   9408  C CG  . LEU D 1 156 ? 136.325 106.505 154.903 1.00 30.23  ? 156 LEU D CG  1 
ATOM   9409  C CD1 . LEU D 1 156 ? 137.010 105.293 154.307 1.00 30.23  ? 156 LEU D CD1 1 
ATOM   9410  C CD2 . LEU D 1 156 ? 135.171 106.078 155.785 1.00 30.23  ? 156 LEU D CD2 1 
ATOM   9411  N N   . GLU D 1 157 ? 138.840 110.282 156.469 1.00 31.36  ? 157 GLU D N   1 
ATOM   9412  C CA  . GLU D 1 157 ? 139.858 110.894 157.305 1.00 31.36  ? 157 GLU D CA  1 
ATOM   9413  C C   . GLU D 1 157 ? 139.198 111.819 158.313 1.00 31.36  ? 157 GLU D C   1 
ATOM   9414  O O   . GLU D 1 157 ? 138.108 112.345 158.075 1.00 31.36  ? 157 GLU D O   1 
ATOM   9415  C CB  . GLU D 1 157 ? 140.881 111.668 156.469 1.00 31.36  ? 157 GLU D CB  1 
ATOM   9416  C CG  . GLU D 1 157 ? 140.566 113.140 156.313 1.00 31.36  ? 157 GLU D CG  1 
ATOM   9417  C CD  . GLU D 1 157 ? 141.621 113.880 155.522 1.00 31.36  ? 157 GLU D CD  1 
ATOM   9418  O OE1 . GLU D 1 157 ? 142.590 113.232 155.083 1.00 31.36  ? 157 GLU D OE1 1 
ATOM   9419  O OE2 . GLU D 1 157 ? 141.482 115.107 155.338 1.00 31.36  ? 157 GLU D OE2 1 
ATOM   9420  N N   . SER D 1 158 ? 139.867 112.004 159.446 1.00 30.52  ? 158 SER D N   1 
ATOM   9421  C CA  . SER D 1 158 ? 139.395 112.935 160.455 1.00 30.52  ? 158 SER D CA  1 
ATOM   9422  C C   . SER D 1 158 ? 139.816 114.352 160.095 1.00 30.52  ? 158 SER D C   1 
ATOM   9423  O O   . SER D 1 158 ? 140.794 114.568 159.375 1.00 30.52  ? 158 SER D O   1 
ATOM   9424  C CB  . SER D 1 158 ? 139.940 112.565 161.831 1.00 30.52  ? 158 SER D CB  1 
ATOM   9425  O OG  . SER D 1 158 ? 141.242 113.087 162.014 1.00 30.52  ? 158 SER D OG  1 
ATOM   9426  N N   . PHE D 1 159 ? 139.062 115.323 160.600 1.00 32.75  ? 159 PHE D N   1 
ATOM   9427  C CA  . PHE D 1 159 ? 139.319 116.724 160.301 1.00 32.75  ? 159 PHE D CA  1 
ATOM   9428  C C   . PHE D 1 159 ? 139.695 117.528 161.533 1.00 32.75  ? 159 PHE D C   1 
ATOM   9429  O O   . PHE D 1 159 ? 140.717 118.223 161.525 1.00 32.75  ? 159 PHE D O   1 
ATOM   9430  C CB  . PHE D 1 159 ? 138.094 117.350 159.626 1.00 32.75  ? 159 PHE D CB  1 
ATOM   9431  C CG  . PHE D 1 159 ? 138.374 118.666 158.975 1.00 32.75  ? 159 PHE D CG  1 
ATOM   9432  C CD1 . PHE D 1 159 ? 139.240 118.749 157.905 1.00 32.75  ? 159 PHE D CD1 1 
ATOM   9433  C CD2 . PHE D 1 159 ? 137.773 119.821 159.433 1.00 32.75  ? 159 PHE D CD2 1 
ATOM   9434  C CE1 . PHE D 1 159 ? 139.499 119.956 157.302 1.00 32.75  ? 159 PHE D CE1 1 
ATOM   9435  C CE2 . PHE D 1 159 ? 138.031 121.031 158.833 1.00 32.75  ? 159 PHE D CE2 1 
ATOM   9436  C CZ  . PHE D 1 159 ? 138.896 121.098 157.767 1.00 32.75  ? 159 PHE D CZ  1 
ATOM   9437  N N   . GLY D 1 160 ? 138.902 117.455 162.593 1.00 34.12  ? 160 GLY D N   1 
ATOM   9438  C CA  . GLY D 1 160 ? 139.139 118.253 163.772 1.00 34.12  ? 160 GLY D CA  1 
ATOM   9439  C C   . GLY D 1 160 ? 140.110 117.686 164.777 1.00 34.12  ? 160 GLY D C   1 
ATOM   9440  O O   . GLY D 1 160 ? 140.310 118.295 165.831 1.00 34.12  ? 160 GLY D O   1 
ATOM   9441  N N   . TYR D 1 161 ? 140.727 116.541 164.498 1.00 36.87  ? 161 TYR D N   1 
ATOM   9442  C CA  . TYR D 1 161 ? 141.594 115.882 165.463 1.00 36.87  ? 161 TYR D CA  1 
ATOM   9443  C C   . TYR D 1 161 ? 142.895 115.461 164.800 1.00 36.87  ? 161 TYR D C   1 
ATOM   9444  O O   . TYR D 1 161 ? 142.885 114.891 163.706 1.00 36.87  ? 161 TYR D O   1 
ATOM   9445  C CB  . TYR D 1 161 ? 140.901 114.665 166.079 1.00 36.87  ? 161 TYR D CB  1 
ATOM   9446  C CG  . TYR D 1 161 ? 139.793 115.018 167.040 1.00 36.87  ? 161 TYR D CG  1 
ATOM   9447  C CD1 . TYR D 1 161 ? 140.070 115.336 168.361 1.00 36.87  ? 161 TYR D CD1 1 
ATOM   9448  C CD2 . TYR D 1 161 ? 138.470 115.032 166.628 1.00 36.87  ? 161 TYR D CD2 1 
ATOM   9449  C CE1 . TYR D 1 161 ? 139.062 115.659 169.242 1.00 36.87  ? 161 TYR D CE1 1 
ATOM   9450  C CE2 . TYR D 1 161 ? 137.455 115.353 167.502 1.00 36.87  ? 161 TYR D CE2 1 
ATOM   9451  C CZ  . TYR D 1 161 ? 137.757 115.666 168.807 1.00 36.87  ? 161 TYR D CZ  1 
ATOM   9452  O OH  . TYR D 1 161 ? 136.747 115.987 169.683 1.00 36.87  ? 161 TYR D OH  1 
ATOM   9453  N N   . THR D 1 162 ? 144.007 115.741 165.470 1.00 38.04  ? 162 THR D N   1 
ATOM   9454  C CA  . THR D 1 162 ? 145.309 115.272 165.026 1.00 38.04  ? 162 THR D CA  1 
ATOM   9455  C C   . THR D 1 162 ? 145.427 113.771 165.279 1.00 38.04  ? 162 THR D C   1 
ATOM   9456  O O   . THR D 1 162 ? 144.745 113.214 166.140 1.00 38.04  ? 162 THR D O   1 
ATOM   9457  C CB  . THR D 1 162 ? 146.412 116.040 165.762 1.00 38.04  ? 162 THR D CB  1 
ATOM   9458  O OG1 . THR D 1 162 ? 146.252 117.442 165.518 1.00 38.04  ? 162 THR D OG1 1 
ATOM   9459  C CG2 . THR D 1 162 ? 147.799 115.630 165.291 1.00 38.04  ? 162 THR D CG2 1 
ATOM   9460  N N   . MET D 1 163 ? 146.299 113.110 164.510 1.00 44.48  ? 163 MET D N   1 
ATOM   9461  C CA  . MET D 1 163 ? 146.523 111.681 164.707 1.00 44.48  ? 163 MET D CA  1 
ATOM   9462  C C   . MET D 1 163 ? 147.018 111.374 166.115 1.00 44.48  ? 163 MET D C   1 
ATOM   9463  O O   . MET D 1 163 ? 146.852 110.244 166.589 1.00 44.48  ? 163 MET D O   1 
ATOM   9464  C CB  . MET D 1 163 ? 147.508 111.153 163.659 1.00 44.48  ? 163 MET D CB  1 
ATOM   9465  C CG  . MET D 1 163 ? 147.954 109.715 163.864 1.00 44.48  ? 163 MET D CG  1 
ATOM   9466  S SD  . MET D 1 163 ? 148.349 108.874 162.323 1.00 44.48  ? 163 MET D SD  1 
ATOM   9467  C CE  . MET D 1 163 ? 149.080 110.214 161.397 1.00 44.48  ? 163 MET D CE  1 
ATOM   9468  N N   . ASN D 1 164 ? 147.582 112.360 166.811 1.00 47.89  ? 164 ASN D N   1 
ATOM   9469  C CA  . ASN D 1 164 ? 147.931 112.171 168.212 1.00 47.89  ? 164 ASN D CA  1 
ATOM   9470  C C   . ASN D 1 164 ? 146.706 111.991 169.097 1.00 47.89  ? 164 ASN D C   1 
ATOM   9471  O O   . ASN D 1 164 ? 146.860 111.629 170.268 1.00 47.89  ? 164 ASN D O   1 
ATOM   9472  C CB  . ASN D 1 164 ? 148.758 113.354 168.712 1.00 47.89  ? 164 ASN D CB  1 
ATOM   9473  C CG  . ASN D 1 164 ? 150.223 113.228 168.360 1.00 47.89  ? 164 ASN D CG  1 
ATOM   9474  O OD1 . ASN D 1 164 ? 150.608 113.360 167.199 1.00 47.89  ? 164 ASN D OD1 1 
ATOM   9475  N ND2 . ASN D 1 164 ? 151.052 112.970 169.363 1.00 47.89  ? 164 ASN D ND2 1 
ATOM   9476  N N   . ASP D 1 165 ? 145.506 112.245 168.580 1.00 46.37  ? 165 ASP D N   1 
ATOM   9477  C CA  . ASP D 1 165 ? 144.264 112.060 169.321 1.00 46.37  ? 165 ASP D CA  1 
ATOM   9478  C C   . ASP D 1 165 ? 143.341 111.016 168.713 1.00 46.37  ? 165 ASP D C   1 
ATOM   9479  O O   . ASP D 1 165 ? 142.733 110.238 169.449 1.00 46.37  ? 165 ASP D O   1 
ATOM   9480  C CB  . ASP D 1 165 ? 143.511 113.390 169.428 1.00 46.37  ? 165 ASP D CB  1 
ATOM   9481  C CG  . ASP D 1 165 ? 144.281 114.434 170.207 1.00 46.37  ? 165 ASP D CG  1 
ATOM   9482  O OD1 . ASP D 1 165 ? 145.328 114.089 170.793 1.00 46.37  ? 165 ASP D OD1 1 
ATOM   9483  O OD2 . ASP D 1 165 ? 143.842 115.603 170.232 1.00 46.37  ? 165 ASP D OD2 1 
ATOM   9484  N N   . LEU D 1 166 ? 143.215 110.978 167.388 1.00 36.42  ? 166 LEU D N   1 
ATOM   9485  C CA  . LEU D 1 166 ? 142.304 110.066 166.710 1.00 36.42  ? 166 LEU D CA  1 
ATOM   9486  C C   . LEU D 1 166 ? 143.072 109.269 165.667 1.00 36.42  ? 166 LEU D C   1 
ATOM   9487  O O   . LEU D 1 166 ? 143.816 109.846 164.869 1.00 36.42  ? 166 LEU D O   1 
ATOM   9488  C CB  . LEU D 1 166 ? 141.156 110.831 166.048 1.00 36.42  ? 166 LEU D CB  1 
ATOM   9489  C CG  . LEU D 1 166 ? 139.868 110.055 165.782 1.00 36.42  ? 166 LEU D CG  1 
ATOM   9490  C CD1 . LEU D 1 166 ? 139.146 109.784 167.082 1.00 36.42  ? 166 LEU D CD1 1 
ATOM   9491  C CD2 . LEU D 1 166 ? 138.975 110.821 164.829 1.00 36.42  ? 166 LEU D CD2 1 
ATOM   9492  N N   . ILE D 1 167 ? 142.888 107.951 165.672 1.00 34.37  ? 167 ILE D N   1 
ATOM   9493  C CA  . ILE D 1 167 ? 143.555 107.055 164.736 1.00 34.37  ? 167 ILE D CA  1 
ATOM   9494  C C   . ILE D 1 167 ? 142.506 106.168 164.084 1.00 34.37  ? 167 ILE D C   1 
ATOM   9495  O O   . ILE D 1 167 ? 141.724 105.512 164.779 1.00 34.37  ? 167 ILE D O   1 
ATOM   9496  C CB  . ILE D 1 167 ? 144.626 106.194 165.431 1.00 34.37  ? 167 ILE D CB  1 
ATOM   9497  C CG1 . ILE D 1 167 ? 145.795 107.063 165.890 1.00 34.37  ? 167 ILE D CG1 1 
ATOM   9498  C CG2 . ILE D 1 167 ? 145.110 105.098 164.504 1.00 34.37  ? 167 ILE D CG2 1 
ATOM   9499  C CD1 . ILE D 1 167 ? 146.902 106.287 166.564 1.00 34.37  ? 167 ILE D CD1 1 
ATOM   9500  N N   . PHE D 1 168 ? 142.496 106.140 162.755 1.00 31.57  ? 168 PHE D N   1 
ATOM   9501  C CA  . PHE D 1 168 ? 141.578 105.305 161.995 1.00 31.57  ? 168 PHE D CA  1 
ATOM   9502  C C   . PHE D 1 168 ? 142.311 104.085 161.456 1.00 31.57  ? 168 PHE D C   1 
ATOM   9503  O O   . PHE D 1 168 ? 143.487 104.167 161.091 1.00 31.57  ? 168 PHE D O   1 
ATOM   9504  C CB  . PHE D 1 168 ? 140.961 106.084 160.833 1.00 31.57  ? 168 PHE D CB  1 
ATOM   9505  C CG  . PHE D 1 168 ? 139.897 107.049 161.247 1.00 31.57  ? 168 PHE D CG  1 
ATOM   9506  C CD1 . PHE D 1 168 ? 139.180 106.853 162.409 1.00 31.57  ? 168 PHE D CD1 1 
ATOM   9507  C CD2 . PHE D 1 168 ? 139.611 108.154 160.469 1.00 31.57  ? 168 PHE D CD2 1 
ATOM   9508  C CE1 . PHE D 1 168 ? 138.200 107.743 162.790 1.00 31.57  ? 168 PHE D CE1 1 
ATOM   9509  C CE2 . PHE D 1 168 ? 138.633 109.046 160.845 1.00 31.57  ? 168 PHE D CE2 1 
ATOM   9510  C CZ  . PHE D 1 168 ? 137.927 108.841 162.007 1.00 31.57  ? 168 PHE D CZ  1 
ATOM   9511  N N   . GLU D 1 169 ? 141.614 102.953 161.408 1.00 32.18  ? 169 GLU D N   1 
ATOM   9512  C CA  . GLU D 1 169 ? 142.182 101.749 160.821 1.00 32.18  ? 169 GLU D CA  1 
ATOM   9513  C C   . GLU D 1 169 ? 141.051 100.832 160.386 1.00 32.18  ? 169 GLU D C   1 
ATOM   9514  O O   . GLU D 1 169 ? 139.990 100.795 161.012 1.00 32.18  ? 169 GLU D O   1 
ATOM   9515  C CB  . GLU D 1 169 ? 143.115 101.031 161.799 1.00 32.18  ? 169 GLU D CB  1 
ATOM   9516  C CG  . GLU D 1 169 ? 142.425 100.432 163.005 1.00 32.18  ? 169 GLU D CG  1 
ATOM   9517  C CD  . GLU D 1 169 ? 143.401 99.786  163.966 1.00 32.18  ? 169 GLU D CD  1 
ATOM   9518  O OE1 . GLU D 1 169 ? 144.576 100.207 163.991 1.00 32.18  ? 169 GLU D OE1 1 
ATOM   9519  O OE2 . GLU D 1 169 ? 142.996 98.857  164.694 1.00 32.18  ? 169 GLU D OE2 1 
ATOM   9520  N N   . TRP D 1 170 ? 141.291 100.097 159.304 1.00 35.54  ? 170 TRP D N   1 
ATOM   9521  C CA  . TRP D 1 170 ? 140.288 99.191  158.771 1.00 35.54  ? 170 TRP D CA  1 
ATOM   9522  C C   . TRP D 1 170 ? 140.067 98.017  159.717 1.00 35.54  ? 170 TRP D C   1 
ATOM   9523  O O   . TRP D 1 170 ? 140.908 97.694  160.558 1.00 35.54  ? 170 TRP D O   1 
ATOM   9524  C CB  . TRP D 1 170 ? 140.713 98.654  157.406 1.00 35.54  ? 170 TRP D CB  1 
ATOM   9525  C CG  . TRP D 1 170 ? 140.461 99.572  156.263 1.00 35.54  ? 170 TRP D CG  1 
ATOM   9526  C CD1 . TRP D 1 170 ? 141.389 100.072 155.407 1.00 35.54  ? 170 TRP D CD1 1 
ATOM   9527  C CD2 . TRP D 1 170 ? 139.198 100.089 155.834 1.00 35.54  ? 170 TRP D CD2 1 
ATOM   9528  N NE1 . TRP D 1 170 ? 140.787 100.874 154.473 1.00 35.54  ? 170 TRP D NE1 1 
ATOM   9529  C CE2 . TRP D 1 170 ? 139.440 100.900 154.714 1.00 35.54  ? 170 TRP D CE2 1 
ATOM   9530  C CE3 . TRP D 1 170 ? 137.887 99.946  156.288 1.00 35.54  ? 170 TRP D CE3 1 
ATOM   9531  C CZ2 . TRP D 1 170 ? 138.423 101.570 154.045 1.00 35.54  ? 170 TRP D CZ2 1 
ATOM   9532  C CZ3 . TRP D 1 170 ? 136.879 100.611 155.622 1.00 35.54  ? 170 TRP D CZ3 1 
ATOM   9533  C CH2 . TRP D 1 170 ? 137.152 101.412 154.513 1.00 35.54  ? 170 TRP D CH2 1 
ATOM   9534  N N   . GLN D 1 171 ? 138.914 97.373  159.570 1.00 48.44  ? 171 GLN D N   1 
ATOM   9535  C CA  . GLN D 1 171 ? 138.680 96.128  160.283 1.00 48.44  ? 171 GLN D CA  1 
ATOM   9536  C C   . GLN D 1 171 ? 139.615 95.047  159.762 1.00 48.44  ? 171 GLN D C   1 
ATOM   9537  O O   . GLN D 1 171 ? 139.944 95.006  158.574 1.00 48.44  ? 171 GLN D O   1 
ATOM   9538  C CB  . GLN D 1 171 ? 137.229 95.680  160.137 1.00 48.44  ? 171 GLN D CB  1 
ATOM   9539  C CG  . GLN D 1 171 ? 136.697 94.974  161.368 1.00 48.44  ? 171 GLN D CG  1 
ATOM   9540  C CD  . GLN D 1 171 ? 135.187 94.963  161.434 1.00 48.44  ? 171 GLN D CD  1 
ATOM   9541  O OE1 . GLN D 1 171 ? 134.521 95.803  160.835 1.00 48.44  ? 171 GLN D OE1 1 
ATOM   9542  N NE2 . GLN D 1 171 ? 134.636 94.001  162.164 1.00 48.44  ? 171 GLN D NE2 1 
ATOM   9543  N N   . ASP D 1 172 ? 140.055 94.172  160.668 1.00 67.48  ? 172 ASP D N   1 
ATOM   9544  C CA  . ASP D 1 172 ? 140.986 93.117  160.283 1.00 67.48  ? 172 ASP D CA  1 
ATOM   9545  C C   . ASP D 1 172 ? 140.346 92.137  159.307 1.00 67.48  ? 172 ASP D C   1 
ATOM   9546  O O   . ASP D 1 172 ? 140.985 91.707  158.340 1.00 67.48  ? 172 ASP D O   1 
ATOM   9547  C CB  . ASP D 1 172 ? 141.490 92.389  161.528 1.00 67.48  ? 172 ASP D CB  1 
ATOM   9548  C CG  . ASP D 1 172 ? 142.027 93.340  162.581 1.00 67.48  ? 172 ASP D CG  1 
ATOM   9549  O OD1 . ASP D 1 172 ? 142.407 94.474  162.221 1.00 67.48  ? 172 ASP D OD1 1 
ATOM   9550  O OD2 . ASP D 1 172 ? 142.068 92.954  163.767 1.00 67.48  ? 172 ASP D OD2 1 
ATOM   9551  N N   . GLU D 1 173 ? 139.087 91.778  159.539 1.00 62.70  ? 173 GLU D N   1 
ATOM   9552  C CA  . GLU D 1 173 ? 138.373 90.815  158.713 1.00 62.70  ? 173 GLU D CA  1 
ATOM   9553  C C   . GLU D 1 173 ? 137.122 91.456  158.131 1.00 62.70  ? 173 GLU D C   1 
ATOM   9554  O O   . GLU D 1 173 ? 136.414 92.197  158.821 1.00 62.70  ? 173 GLU D O   1 
ATOM   9555  C CB  . GLU D 1 173 ? 137.998 89.566  159.520 1.00 62.70  ? 173 GLU D CB  1 
ATOM   9556  C CG  . GLU D 1 173 ? 137.184 89.847  160.777 1.00 62.70  ? 173 GLU D CG  1 
ATOM   9557  C CD  . GLU D 1 173 ? 138.045 90.276  161.950 1.00 62.70  ? 173 GLU D CD  1 
ATOM   9558  O OE1 . GLU D 1 173 ? 139.273 90.055  161.898 1.00 62.70  ? 173 GLU D OE1 1 
ATOM   9559  O OE2 . GLU D 1 173 ? 137.496 90.837  162.921 1.00 62.70  ? 173 GLU D OE2 1 
ATOM   9560  N N   . ALA D 1 174 ? 136.857 91.165  156.856 1.00 49.78  ? 174 ALA D N   1 
ATOM   9561  C CA  . ALA D 1 174 ? 135.713 91.693  156.121 1.00 49.78  ? 174 ALA D CA  1 
ATOM   9562  C C   . ALA D 1 174 ? 135.664 93.214  156.211 1.00 49.78  ? 174 ALA D C   1 
ATOM   9563  O O   . ALA D 1 174 ? 134.741 93.768  156.818 1.00 49.78  ? 174 ALA D O   1 
ATOM   9564  C CB  . ALA D 1 174 ? 134.410 91.088  156.644 1.00 49.78  ? 174 ALA D CB  1 
ATOM   9565  N N   . PRO D 1 175 ? 136.631 93.923  155.622 1.00 36.64  ? 175 PRO D N   1 
ATOM   9566  C CA  . PRO D 1 175 ? 136.620 95.387  155.751 1.00 36.64  ? 175 PRO D CA  1 
ATOM   9567  C C   . PRO D 1 175 ? 135.532 96.050  154.933 1.00 36.64  ? 175 PRO D C   1 
ATOM   9568  O O   . PRO D 1 175 ? 134.897 96.996  155.412 1.00 36.64  ? 175 PRO D O   1 
ATOM   9569  C CB  . PRO D 1 175 ? 138.020 95.782  155.271 1.00 36.64  ? 175 PRO D CB  1 
ATOM   9570  C CG  . PRO D 1 175 ? 138.377 94.725  154.291 1.00 36.64  ? 175 PRO D CG  1 
ATOM   9571  C CD  . PRO D 1 175 ? 137.742 93.449  154.780 1.00 36.64  ? 175 PRO D CD  1 
ATOM   9572  N N   . VAL D 1 176 ? 135.297 95.590  153.708 1.00 30.98  ? 176 VAL D N   1 
ATOM   9573  C CA  . VAL D 1 176 ? 134.271 96.151  152.840 1.00 30.98  ? 176 VAL D CA  1 
ATOM   9574  C C   . VAL D 1 176 ? 133.372 95.021  152.368 1.00 30.98  ? 176 VAL D C   1 
ATOM   9575  O O   . VAL D 1 176 ? 133.854 94.032  151.807 1.00 30.98  ? 176 VAL D O   1 
ATOM   9576  C CB  . VAL D 1 176 ? 134.879 96.894  151.637 1.00 30.98  ? 176 VAL D CB  1 
ATOM   9577  C CG1 . VAL D 1 176 ? 133.789 97.317  150.676 1.00 30.98  ? 176 VAL D CG1 1 
ATOM   9578  C CG2 . VAL D 1 176 ? 135.668 98.097  152.106 1.00 30.98  ? 176 VAL D CG2 1 
ATOM   9579  N N   . GLN D 1 177 ? 132.072 95.169  152.590 1.00 33.05  ? 177 GLN D N   1 
ATOM   9580  C CA  . GLN D 1 177 ? 131.083 94.202  152.146 1.00 33.05  ? 177 GLN D CA  1 
ATOM   9581  C C   . GLN D 1 177 ? 130.240 94.805  151.032 1.00 33.05  ? 177 GLN D C   1 
ATOM   9582  O O   . GLN D 1 177 ? 130.010 96.016  150.990 1.00 33.05  ? 177 GLN D O   1 
ATOM   9583  C CB  . GLN D 1 177 ? 130.183 93.761  153.300 1.00 33.05  ? 177 GLN D CB  1 
ATOM   9584  C CG  . GLN D 1 177 ? 130.908 92.976  154.373 1.00 33.05  ? 177 GLN D CG  1 
ATOM   9585  C CD  . GLN D 1 177 ? 130.698 93.549  155.756 1.00 33.05  ? 177 GLN D CD  1 
ATOM   9586  O OE1 . GLN D 1 177 ? 129.756 94.305  155.990 1.00 33.05  ? 177 GLN D OE1 1 
ATOM   9587  N NE2 . GLN D 1 177 ? 131.578 93.194  156.683 1.00 33.05  ? 177 GLN D NE2 1 
ATOM   9588  N N   . VAL D 1 178 ? 129.786 93.949  150.123 1.00 29.69  ? 178 VAL D N   1 
ATOM   9589  C CA  . VAL D 1 178 ? 128.986 94.361  148.978 1.00 29.69  ? 178 VAL D CA  1 
ATOM   9590  C C   . VAL D 1 178 ? 127.674 93.594  149.009 1.00 29.69  ? 178 VAL D C   1 
ATOM   9591  O O   . VAL D 1 178 ? 127.670 92.370  149.180 1.00 29.69  ? 178 VAL D O   1 
ATOM   9592  C CB  . VAL D 1 178 ? 129.731 94.123  147.653 1.00 29.69  ? 178 VAL D CB  1 
ATOM   9593  C CG1 . VAL D 1 178 ? 128.811 94.376  146.483 1.00 29.69  ? 178 VAL D CG1 1 
ATOM   9594  C CG2 . VAL D 1 178 ? 130.951 95.018  147.573 1.00 29.69  ? 178 VAL D CG2 1 
ATOM   9595  N N   . ALA D 1 179 ? 126.566 94.314  148.855 1.00 33.61  ? 179 ALA D N   1 
ATOM   9596  C CA  . ALA D 1 179 ? 125.255 93.683  148.879 1.00 33.61  ? 179 ALA D CA  1 
ATOM   9597  C C   . ALA D 1 179 ? 125.110 92.711  147.718 1.00 33.61  ? 179 ALA D C   1 
ATOM   9598  O O   . ALA D 1 179 ? 125.628 92.943  146.623 1.00 33.61  ? 179 ALA D O   1 
ATOM   9599  C CB  . ALA D 1 179 ? 124.155 94.741  148.819 1.00 33.61  ? 179 ALA D CB  1 
ATOM   9600  N N   . GLU D 1 180 ? 124.402 91.614  147.967 1.00 36.54  ? 180 GLU D N   1 
ATOM   9601  C CA  . GLU D 1 180 ? 124.236 90.583  146.953 1.00 36.54  ? 180 GLU D CA  1 
ATOM   9602  C C   . GLU D 1 180 ? 123.447 91.118  145.766 1.00 36.54  ? 180 GLU D C   1 
ATOM   9603  O O   . GLU D 1 180 ? 122.536 91.934  145.919 1.00 36.54  ? 180 GLU D O   1 
ATOM   9604  C CB  . GLU D 1 180 ? 123.531 89.364  147.545 1.00 36.54  ? 180 GLU D CB  1 
ATOM   9605  N N   . GLY D 1 181 ? 123.808 90.654  144.574 1.00 42.34  ? 181 GLY D N   1 
ATOM   9606  C CA  . GLY D 1 181 ? 123.102 91.052  143.375 1.00 42.34  ? 181 GLY D CA  1 
ATOM   9607  C C   . GLY D 1 181 ? 123.370 92.460  142.902 1.00 42.34  ? 181 GLY D C   1 
ATOM   9608  O O   . GLY D 1 181 ? 122.540 93.025  142.184 1.00 42.34  ? 181 GLY D O   1 
ATOM   9609  N N   . LEU D 1 182 ? 124.499 93.051  143.283 1.00 48.45  ? 182 LEU D N   1 
ATOM   9610  C CA  . LEU D 1 182 ? 124.844 94.383  142.806 1.00 48.45  ? 182 LEU D CA  1 
ATOM   9611  C C   . LEU D 1 182 ? 125.354 94.297  141.375 1.00 48.45  ? 182 LEU D C   1 
ATOM   9612  O O   . LEU D 1 182 ? 126.251 93.506  141.072 1.00 48.45  ? 182 LEU D O   1 
ATOM   9613  C CB  . LEU D 1 182 ? 125.902 95.025  143.704 1.00 48.45  ? 182 LEU D CB  1 
ATOM   9614  C CG  . LEU D 1 182 ? 126.680 96.198  143.098 1.00 48.45  ? 182 LEU D CG  1 
ATOM   9615  C CD1 . LEU D 1 182 ? 125.741 97.332  142.707 1.00 48.45  ? 182 LEU D CD1 1 
ATOM   9616  C CD2 . LEU D 1 182 ? 127.753 96.700  144.042 1.00 48.45  ? 182 LEU D CD2 1 
ATOM   9617  N N   . THR D 1 183 ? 124.784 95.119  140.499 1.00 56.00  ? 183 THR D N   1 
ATOM   9618  C CA  . THR D 1 183 ? 125.199 95.193  139.109 1.00 56.00  ? 183 THR D CA  1 
ATOM   9619  C C   . THR D 1 183 ? 125.372 96.650  138.711 1.00 56.00  ? 183 THR D C   1 
ATOM   9620  O O   . THR D 1 183 ? 124.758 97.548  139.292 1.00 56.00  ? 183 THR D O   1 
ATOM   9621  C CB  . THR D 1 183 ? 124.188 94.519  138.172 1.00 56.00  ? 183 THR D CB  1 
ATOM   9622  O OG1 . THR D 1 183 ? 124.544 94.788  136.811 1.00 56.00  ? 183 THR D OG1 1 
ATOM   9623  C CG2 . THR D 1 183 ? 122.786 95.042  138.437 1.00 56.00  ? 183 THR D CG2 1 
ATOM   9624  N N   . LEU D 1 184 ? 126.219 96.874  137.713 1.00 49.26  ? 184 LEU D N   1 
ATOM   9625  C CA  . LEU D 1 184 ? 126.464 98.213  137.215 1.00 49.26  ? 184 LEU D CA  1 
ATOM   9626  C C   . LEU D 1 184 ? 126.029 98.315  135.759 1.00 49.26  ? 184 LEU D C   1 
ATOM   9627  O O   . LEU D 1 184 ? 126.079 97.325  135.022 1.00 49.26  ? 184 LEU D O   1 
ATOM   9628  C CB  . LEU D 1 184 ? 127.947 98.588  137.338 1.00 49.26  ? 184 LEU D CB  1 
ATOM   9629  C CG  . LEU D 1 184 ? 128.394 99.124  138.699 1.00 49.26  ? 184 LEU D CG  1 
ATOM   9630  C CD1 . LEU D 1 184 ? 128.535 97.997  139.706 1.00 49.26  ? 184 LEU D CD1 1 
ATOM   9631  C CD2 . LEU D 1 184 ? 129.697 99.891  138.567 1.00 49.26  ? 184 LEU D CD2 1 
ATOM   9632  N N   . PRO D 1 185 ? 125.579 99.492  135.321 1.00 52.68  ? 185 PRO D N   1 
ATOM   9633  C CA  . PRO D 1 185 ? 125.130 99.623  133.927 1.00 52.68  ? 185 PRO D CA  1 
ATOM   9634  C C   . PRO D 1 185 ? 126.217 99.344  132.906 1.00 52.68  ? 185 PRO D C   1 
ATOM   9635  O O   . PRO D 1 185 ? 125.918 98.812  131.830 1.00 52.68  ? 185 PRO D O   1 
ATOM   9636  C CB  . PRO D 1 185 ? 124.645 101.078 133.853 1.00 52.68  ? 185 PRO D CB  1 
ATOM   9637  C CG  . PRO D 1 185 ? 125.366 101.774 134.960 1.00 52.68  ? 185 PRO D CG  1 
ATOM   9638  C CD  . PRO D 1 185 ? 125.479 100.763 136.057 1.00 52.68  ? 185 PRO D CD  1 
ATOM   9639  N N   . GLN D 1 186 ? 127.473 99.680  133.206 1.00 54.07  ? 186 GLN D N   1 
ATOM   9640  C CA  . GLN D 1 186 ? 128.530 99.553  132.212 1.00 54.07  ? 186 GLN D CA  1 
ATOM   9641  C C   . GLN D 1 186 ? 129.834 98.998  132.773 1.00 54.07  ? 186 GLN D C   1 
ATOM   9642  O O   . GLN D 1 186 ? 130.832 98.961  132.044 1.00 54.07  ? 186 GLN D O   1 
ATOM   9643  C CB  . GLN D 1 186 ? 128.797 100.911 131.550 1.00 54.07  ? 186 GLN D CB  1 
ATOM   9644  C CG  . GLN D 1 186 ? 128.290 101.029 130.123 1.00 54.07  ? 186 GLN D CG  1 
ATOM   9645  C CD  . GLN D 1 186 ? 129.221 100.389 129.111 1.00 54.07  ? 186 GLN D CD  1 
ATOM   9646  O OE1 . GLN D 1 186 ? 129.854 99.370  129.384 1.00 54.07  ? 186 GLN D OE1 1 
ATOM   9647  N NE2 . GLN D 1 186 ? 129.312 100.991 127.932 1.00 54.07  ? 186 GLN D NE2 1 
ATOM   9648  N N   . PHE D 1 187 ? 129.870 98.577  134.034 1.00 50.53  ? 187 PHE D N   1 
ATOM   9649  C CA  . PHE D 1 187 ? 131.099 98.100  134.649 1.00 50.53  ? 187 PHE D CA  1 
ATOM   9650  C C   . PHE D 1 187 ? 130.798 96.837  135.442 1.00 50.53  ? 187 PHE D C   1 
ATOM   9651  O O   . PHE D 1 187 ? 129.660 96.360  135.487 1.00 50.53  ? 187 PHE D O   1 
ATOM   9652  C CB  . PHE D 1 187 ? 131.722 99.167  135.557 1.00 50.53  ? 187 PHE D CB  1 
ATOM   9653  C CG  . PHE D 1 187 ? 132.100 100.435 134.845 1.00 50.53  ? 187 PHE D CG  1 
ATOM   9654  C CD1 . PHE D 1 187 ? 131.144 101.384 134.534 1.00 50.53  ? 187 PHE D CD1 1 
ATOM   9655  C CD2 . PHE D 1 187 ? 133.416 100.686 134.505 1.00 50.53  ? 187 PHE D CD2 1 
ATOM   9656  C CE1 . PHE D 1 187 ? 131.490 102.549 133.886 1.00 50.53  ? 187 PHE D CE1 1 
ATOM   9657  C CE2 . PHE D 1 187 ? 133.767 101.851 133.859 1.00 50.53  ? 187 PHE D CE2 1 
ATOM   9658  C CZ  . PHE D 1 187 ? 132.802 102.782 133.550 1.00 50.53  ? 187 PHE D CZ  1 
ATOM   9659  N N   . LEU D 1 188 ? 131.835 96.289  136.070 1.00 51.63  ? 188 LEU D N   1 
ATOM   9660  C CA  . LEU D 1 188 ? 131.676 95.180  136.998 1.00 51.63  ? 188 LEU D CA  1 
ATOM   9661  C C   . LEU D 1 188 ? 132.741 95.297  138.077 1.00 51.63  ? 188 LEU D C   1 
ATOM   9662  O O   . LEU D 1 188 ? 133.901 95.595  137.784 1.00 51.63  ? 188 LEU D O   1 
ATOM   9663  C CB  . LEU D 1 188 ? 131.774 93.825  136.290 1.00 51.63  ? 188 LEU D CB  1 
ATOM   9664  C CG  . LEU D 1 188 ? 133.015 93.563  135.442 1.00 51.63  ? 188 LEU D CG  1 
ATOM   9665  C CD1 . LEU D 1 188 ? 133.500 92.142  135.657 1.00 51.63  ? 188 LEU D CD1 1 
ATOM   9666  C CD2 . LEU D 1 188 ? 132.714 93.809  133.976 1.00 51.63  ? 188 LEU D CD2 1 
ATOM   9667  N N   . LEU D 1 189 ? 132.338 95.062  139.322 1.00 49.10  ? 189 LEU D N   1 
ATOM   9668  C CA  . LEU D 1 189 ? 133.219 95.232  140.469 1.00 49.10  ? 189 LEU D CA  1 
ATOM   9669  C C   . LEU D 1 189 ? 133.976 93.936  140.726 1.00 49.10  ? 189 LEU D C   1 
ATOM   9670  O O   . LEU D 1 189 ? 133.364 92.898  141.001 1.00 49.10  ? 189 LEU D O   1 
ATOM   9671  C CB  . LEU D 1 189 ? 132.419 95.636  141.704 1.00 49.10  ? 189 LEU D CB  1 
ATOM   9672  C CG  . LEU D 1 189 ? 132.478 97.104  142.118 1.00 49.10  ? 189 LEU D CG  1 
ATOM   9673  C CD1 . LEU D 1 189 ? 133.812 97.421  142.764 1.00 49.10  ? 189 LEU D CD1 1 
ATOM   9674  C CD2 . LEU D 1 189 ? 132.235 97.999  140.918 1.00 49.10  ? 189 LEU D CD2 1 
ATOM   9675  N N   . LYS D 1 190 ? 135.301 93.997  140.639 1.00 56.47  ? 190 LYS D N   1 
ATOM   9676  C CA  . LYS D 1 190 ? 136.118 92.833  140.944 1.00 56.47  ? 190 LYS D CA  1 
ATOM   9677  C C   . LYS D 1 190 ? 136.106 92.561  142.444 1.00 56.47  ? 190 LYS D C   1 
ATOM   9678  O O   . LYS D 1 190 ? 135.875 93.457  143.259 1.00 56.47  ? 190 LYS D O   1 
ATOM   9679  C CB  . LYS D 1 190 ? 137.548 93.040  140.449 1.00 56.47  ? 190 LYS D CB  1 
ATOM   9680  C CG  . LYS D 1 190 ? 137.656 93.191  138.940 1.00 56.47  ? 190 LYS D CG  1 
ATOM   9681  C CD  . LYS D 1 190 ? 138.933 92.569  138.404 1.00 56.47  ? 190 LYS D CD  1 
ATOM   9682  C CE  . LYS D 1 190 ? 140.152 93.368  138.825 1.00 56.47  ? 190 LYS D CE  1 
ATOM   9683  N NZ  . LYS D 1 190 ? 140.122 94.755  138.291 1.00 56.47  ? 190 LYS D NZ  1 
ATOM   9684  N N   . GLU D 1 191 ? 136.351 91.300  142.805 1.00 63.58  ? 191 GLU D N   1 
ATOM   9685  C CA  . GLU D 1 191 ? 136.250 90.900  144.205 1.00 63.58  ? 191 GLU D CA  1 
ATOM   9686  C C   . GLU D 1 191 ? 137.331 91.557  145.057 1.00 63.58  ? 191 GLU D C   1 
ATOM   9687  O O   . GLU D 1 191 ? 137.079 91.925  146.209 1.00 63.58  ? 191 GLU D O   1 
ATOM   9688  C CB  . GLU D 1 191 ? 136.282 89.371  144.312 1.00 63.58  ? 191 GLU D CB  1 
ATOM   9689  C CG  . GLU D 1 191 ? 137.546 88.659  143.802 1.00 63.58  ? 191 GLU D CG  1 
ATOM   9690  C CD  . GLU D 1 191 ? 138.743 88.751  144.738 1.00 63.58  ? 191 GLU D CD  1 
ATOM   9691  O OE1 . GLU D 1 191 ? 139.852 88.366  144.313 1.00 63.58  ? 191 GLU D OE1 1 
ATOM   9692  O OE2 . GLU D 1 191 ? 138.573 89.150  145.909 1.00 63.58  ? 191 GLU D OE2 1 
ATOM   9693  N N   . GLU D 1 192 ? 138.538 91.703  144.519 1.00 57.26  ? 192 GLU D N   1 
ATOM   9694  C CA  . GLU D 1 192 ? 139.648 92.239  145.295 1.00 57.26  ? 192 GLU D CA  1 
ATOM   9695  C C   . GLU D 1 192 ? 139.535 93.754  145.415 1.00 57.26  ? 192 GLU D C   1 
ATOM   9696  O O   . GLU D 1 192 ? 139.299 94.450  144.423 1.00 57.26  ? 192 GLU D O   1 
ATOM   9697  C CB  . GLU D 1 192 ? 140.982 91.850  144.661 1.00 57.26  ? 192 GLU D CB  1 
ATOM   9698  C CG  . GLU D 1 192 ? 141.053 92.073  143.162 1.00 57.26  ? 192 GLU D CG  1 
ATOM   9699  C CD  . GLU D 1 192 ? 141.748 93.366  142.796 1.00 57.26  ? 192 GLU D CD  1 
ATOM   9700  O OE1 . GLU D 1 192 ? 142.282 94.036  143.704 1.00 57.26  ? 192 GLU D OE1 1 
ATOM   9701  O OE2 . GLU D 1 192 ? 141.765 93.711  141.597 1.00 57.26  ? 192 GLU D OE2 1 
ATOM   9702  N N   . LYS D 1 193 ? 139.696 94.257  146.637 1.00 46.14  ? 193 LYS D N   1 
ATOM   9703  C CA  . LYS D 1 193 ? 139.683 95.686  146.916 1.00 46.14  ? 193 LYS D CA  1 
ATOM   9704  C C   . LYS D 1 193 ? 140.880 96.019  147.791 1.00 46.14  ? 193 LYS D C   1 
ATOM   9705  O O   . LYS D 1 193 ? 141.096 95.373  148.820 1.00 46.14  ? 193 LYS D O   1 
ATOM   9706  C CB  . LYS D 1 193 ? 138.383 96.101  147.608 1.00 46.14  ? 193 LYS D CB  1 
ATOM   9707  C CG  . LYS D 1 193 ? 137.136 95.792  146.805 1.00 46.14  ? 193 LYS D CG  1 
ATOM   9708  C CD  . LYS D 1 193 ? 135.887 96.186  147.563 1.00 46.14  ? 193 LYS D CD  1 
ATOM   9709  C CE  . LYS D 1 193 ? 134.646 95.982  146.716 1.00 46.14  ? 193 LYS D CE  1 
ATOM   9710  N NZ  . LYS D 1 193 ? 134.455 94.552  146.362 1.00 46.14  ? 193 LYS D NZ  1 
ATOM   9711  N N   . ASP D 1 194 ? 141.650 97.023  147.386 1.00 44.22  ? 194 ASP D N   1 
ATOM   9712  C CA  . ASP D 1 194 ? 142.864 97.392  148.096 1.00 44.22  ? 194 ASP D CA  1 
ATOM   9713  C C   . ASP D 1 194 ? 142.549 98.329  149.254 1.00 44.22  ? 194 ASP D C   1 
ATOM   9714  O O   . ASP D 1 194 ? 141.605 99.120  149.201 1.00 44.22  ? 194 ASP D O   1 
ATOM   9715  C CB  . ASP D 1 194 ? 143.861 98.057  147.148 1.00 44.22  ? 194 ASP D CB  1 
ATOM   9716  C CG  . ASP D 1 194 ? 144.090 97.252  145.886 1.00 44.22  ? 194 ASP D CG  1 
ATOM   9717  O OD1 . ASP D 1 194 ? 143.469 96.179  145.746 1.00 44.22  ? 194 ASP D OD1 1 
ATOM   9718  O OD2 . ASP D 1 194 ? 144.891 97.693  145.035 1.00 44.22  ? 194 ASP D OD2 1 
ATOM   9719  N N   . LEU D 1 195 ? 143.356 98.231  150.308 1.00 36.75  ? 195 LEU D N   1 
ATOM   9720  C CA  . LEU D 1 195 ? 143.219 99.075  151.489 1.00 36.75  ? 195 LEU D CA  1 
ATOM   9721  C C   . LEU D 1 195 ? 144.568 99.711  151.782 1.00 36.75  ? 195 LEU D C   1 
ATOM   9722  O O   . LEU D 1 195 ? 145.568 99.003  151.934 1.00 36.75  ? 195 LEU D O   1 
ATOM   9723  C CB  . LEU D 1 195 ? 142.731 98.263  152.691 1.00 36.75  ? 195 LEU D CB  1 
ATOM   9724  C CG  . LEU D 1 195 ? 141.807 97.083  152.386 1.00 36.75  ? 195 LEU D CG  1 
ATOM   9725  C CD1 . LEU D 1 195 ? 141.686 96.172  153.594 1.00 36.75  ? 195 LEU D CD1 1 
ATOM   9726  C CD2 . LEU D 1 195 ? 140.439 97.568  151.947 1.00 36.75  ? 195 LEU D CD2 1 
ATOM   9727  N N   . ARG D 1 196 ? 144.598 101.040 151.864 1.00 39.45  ? 196 ARG D N   1 
ATOM   9728  C CA  . ARG D 1 196 ? 145.837 101.785 152.032 1.00 39.45  ? 196 ARG D CA  1 
ATOM   9729  C C   . ARG D 1 196 ? 145.661 102.862 153.093 1.00 39.45  ? 196 ARG D C   1 
ATOM   9730  O O   . ARG D 1 196 ? 144.544 103.270 153.415 1.00 39.45  ? 196 ARG D O   1 
ATOM   9731  C CB  . ARG D 1 196 ? 146.294 102.427 150.713 1.00 39.45  ? 196 ARG D CB  1 
ATOM   9732  C CG  . ARG D 1 196 ? 146.234 101.499 149.516 1.00 39.45  ? 196 ARG D CG  1 
ATOM   9733  C CD  . ARG D 1 196 ? 147.121 101.986 148.389 1.00 39.45  ? 196 ARG D CD  1 
ATOM   9734  N NE  . ARG D 1 196 ? 146.517 101.736 147.086 1.00 39.45  ? 196 ARG D NE  1 
ATOM   9735  C CZ  . ARG D 1 196 ? 146.633 100.598 146.416 1.00 39.45  ? 196 ARG D CZ  1 
ATOM   9736  N NH1 . ARG D 1 196 ? 147.327 99.580  146.898 1.00 39.45  ? 196 ARG D NH1 1 
ATOM   9737  N NH2 . ARG D 1 196 ? 146.037 100.477 145.233 1.00 39.45  ? 196 ARG D NH2 1 
ATOM   9738  N N   . TYR D 1 197 ? 146.788 103.318 153.637 1.00 34.41  ? 197 TYR D N   1 
ATOM   9739  C CA  . TYR D 1 197 ? 146.819 104.374 154.644 1.00 34.41  ? 197 TYR D CA  1 
ATOM   9740  C C   . TYR D 1 197 ? 147.389 105.632 154.001 1.00 34.41  ? 197 TYR D C   1 
ATOM   9741  O O   . TYR D 1 197 ? 148.598 105.723 153.770 1.00 34.41  ? 197 TYR D O   1 
ATOM   9742  C CB  . TYR D 1 197 ? 147.651 103.963 155.857 1.00 34.41  ? 197 TYR D CB  1 
ATOM   9743  C CG  . TYR D 1 197 ? 147.153 102.741 156.597 1.00 34.41  ? 197 TYR D CG  1 
ATOM   9744  C CD1 . TYR D 1 197 ? 145.895 102.213 156.350 1.00 34.41  ? 197 TYR D CD1 1 
ATOM   9745  C CD2 . TYR D 1 197 ? 147.946 102.119 157.552 1.00 34.41  ? 197 TYR D CD2 1 
ATOM   9746  C CE1 . TYR D 1 197 ? 145.442 101.097 157.026 1.00 34.41  ? 197 TYR D CE1 1 
ATOM   9747  C CE2 . TYR D 1 197 ? 147.501 101.004 158.234 1.00 34.41  ? 197 TYR D CE2 1 
ATOM   9748  C CZ  . TYR D 1 197 ? 146.249 100.498 157.967 1.00 34.41  ? 197 TYR D CZ  1 
ATOM   9749  O OH  . TYR D 1 197 ? 145.803 99.387  158.644 1.00 34.41  ? 197 TYR D OH  1 
ATOM   9750  N N   . CYS D 1 198 ? 146.518 106.601 153.715 1.00 33.38  ? 198 CYS D N   1 
ATOM   9751  C CA  . CYS D 1 198 ? 146.968 107.848 153.104 1.00 33.38  ? 198 CYS D CA  1 
ATOM   9752  C C   . CYS D 1 198 ? 147.719 108.719 154.105 1.00 33.38  ? 198 CYS D C   1 
ATOM   9753  O O   . CYS D 1 198 ? 148.787 109.256 153.790 1.00 33.38  ? 198 CYS D O   1 
ATOM   9754  C CB  . CYS D 1 198 ? 145.771 108.593 152.515 1.00 33.38  ? 198 CYS D CB  1 
ATOM   9755  S SG  . CYS D 1 198 ? 144.178 108.025 153.156 1.00 33.38  ? 198 CYS D SG  1 
ATOM   9756  N N   . THR D 1 199 ? 147.176 108.857 155.316 1.00 31.96  ? 199 THR D N   1 
ATOM   9757  C CA  . THR D 1 199 ? 147.735 109.648 156.424 1.00 31.96  ? 199 THR D CA  1 
ATOM   9758  C C   . THR D 1 199 ? 148.420 110.925 155.935 1.00 31.96  ? 199 THR D C   1 
ATOM   9759  O O   . THR D 1 199 ? 149.601 111.170 156.178 1.00 31.96  ? 199 THR D O   1 
ATOM   9760  C CB  . THR D 1 199 ? 148.678 108.820 157.307 1.00 31.96  ? 199 THR D CB  1 
ATOM   9761  O OG1 . THR D 1 199 ? 149.356 109.692 158.220 1.00 31.96  ? 199 THR D OG1 1 
ATOM   9762  C CG2 . THR D 1 199 ? 149.717 108.048 156.500 1.00 31.96  ? 199 THR D CG2 1 
ATOM   9763  N N   . LYS D 1 200 ? 147.642 111.751 155.242 1.00 31.14  ? 200 LYS D N   1 
ATOM   9764  C CA  . LYS D 1 200 ? 148.182 112.960 154.642 1.00 31.14  ? 200 LYS D CA  1 
ATOM   9765  C C   . LYS D 1 200 ? 148.587 113.974 155.709 1.00 31.14  ? 200 LYS D C   1 
ATOM   9766  O O   . LYS D 1 200 ? 148.046 114.008 156.816 1.00 31.14  ? 200 LYS D O   1 
ATOM   9767  C CB  . LYS D 1 200 ? 147.169 113.588 153.688 1.00 31.14  ? 200 LYS D CB  1 
ATOM   9768  C CG  . LYS D 1 200 ? 145.730 113.481 154.143 1.00 31.14  ? 200 LYS D CG  1 
ATOM   9769  C CD  . LYS D 1 200 ? 144.812 113.224 152.961 1.00 31.14  ? 200 LYS D CD  1 
ATOM   9770  C CE  . LYS D 1 200 ? 144.981 114.285 151.889 1.00 31.14  ? 200 LYS D CE  1 
ATOM   9771  N NZ  . LYS D 1 200 ? 144.112 114.027 150.710 1.00 31.14  ? 200 LYS D NZ  1 
ATOM   9772  N N   . HIS D 1 201 ? 149.560 114.807 155.352 1.00 34.25  ? 201 HIS D N   1 
ATOM   9773  C CA  . HIS D 1 201 ? 150.075 115.858 156.216 1.00 34.25  ? 201 HIS D CA  1 
ATOM   9774  C C   . HIS D 1 201 ? 149.549 117.210 155.757 1.00 34.25  ? 201 HIS D C   1 
ATOM   9775  O O   . HIS D 1 201 ? 149.453 117.473 154.555 1.00 34.25  ? 201 HIS D O   1 
ATOM   9776  C CB  . HIS D 1 201 ? 151.606 115.886 156.205 1.00 34.25  ? 201 HIS D CB  1 
ATOM   9777  C CG  . HIS D 1 201 ? 152.241 114.679 156.819 1.00 34.25  ? 201 HIS D CG  1 
ATOM   9778  N ND1 . HIS D 1 201 ? 152.391 113.490 156.139 1.00 34.25  ? 201 HIS D ND1 1 
ATOM   9779  C CD2 . HIS D 1 201 ? 152.778 114.482 158.045 1.00 34.25  ? 201 HIS D CD2 1 
ATOM   9780  C CE1 . HIS D 1 201 ? 152.986 112.610 156.923 1.00 34.25  ? 201 HIS D CE1 1 
ATOM   9781  N NE2 . HIS D 1 201 ? 153.232 113.187 158.085 1.00 34.25  ? 201 HIS D NE2 1 
ATOM   9782  N N   . TYR D 1 202 ? 149.215 118.063 156.715 1.00 36.11  ? 202 TYR D N   1 
ATOM   9783  C CA  . TYR D 1 202 ? 148.822 119.439 156.450 1.00 36.11  ? 202 TYR D CA  1 
ATOM   9784  C C   . TYR D 1 202 ? 149.731 120.378 157.235 1.00 36.11  ? 202 TYR D C   1 
ATOM   9785  O O   . TYR D 1 202 ? 150.609 119.947 157.985 1.00 36.11  ? 202 TYR D O   1 
ATOM   9786  C CB  . TYR D 1 202 ? 147.354 119.671 156.811 1.00 36.11  ? 202 TYR D CB  1 
ATOM   9787  C CG  . TYR D 1 202 ? 146.377 118.996 155.883 1.00 36.11  ? 202 TYR D CG  1 
ATOM   9788  C CD1 . TYR D 1 202 ? 146.623 118.921 154.522 1.00 36.11  ? 202 TYR D CD1 1 
ATOM   9789  C CD2 . TYR D 1 202 ? 145.205 118.436 156.368 1.00 36.11  ? 202 TYR D CD2 1 
ATOM   9790  C CE1 . TYR D 1 202 ? 145.730 118.306 153.671 1.00 36.11  ? 202 TYR D CE1 1 
ATOM   9791  C CE2 . TYR D 1 202 ? 144.308 117.819 155.525 1.00 36.11  ? 202 TYR D CE2 1 
ATOM   9792  C CZ  . TYR D 1 202 ? 144.575 117.756 154.178 1.00 36.11  ? 202 TYR D CZ  1 
ATOM   9793  O OH  . TYR D 1 202 ? 143.682 117.141 153.333 1.00 36.11  ? 202 TYR D OH  1 
ATOM   9794  N N   . ASN D 1 203 ? 149.513 121.681 157.053 1.00 36.80  ? 203 ASN D N   1 
ATOM   9795  C CA  . ASN D 1 203 ? 150.287 122.665 157.800 1.00 36.80  ? 203 ASN D CA  1 
ATOM   9796  C C   . ASN D 1 203 ? 149.860 122.745 159.257 1.00 36.80  ? 203 ASN D C   1 
ATOM   9797  O O   . ASN D 1 203 ? 150.626 123.246 160.087 1.00 36.80  ? 203 ASN D O   1 
ATOM   9798  C CB  . ASN D 1 203 ? 150.156 124.040 157.153 1.00 36.80  ? 203 ASN D CB  1 
ATOM   9799  C CG  . ASN D 1 203 ? 150.219 123.979 155.647 1.00 36.80  ? 203 ASN D CG  1 
ATOM   9800  O OD1 . ASN D 1 203 ? 150.038 122.919 155.051 1.00 36.80  ? 203 ASN D OD1 1 
ATOM   9801  N ND2 . ASN D 1 203 ? 150.473 125.119 155.019 1.00 36.80  ? 203 ASN D ND2 1 
ATOM   9802  N N   . THR D 1 204 ? 148.663 122.269 159.586 1.00 35.86  ? 204 THR D N   1 
ATOM   9803  C CA  . THR D 1 204 ? 148.136 122.353 160.938 1.00 35.86  ? 204 THR D CA  1 
ATOM   9804  C C   . THR D 1 204 ? 148.339 121.078 161.743 1.00 35.86  ? 204 THR D C   1 
ATOM   9805  O O   . THR D 1 204 ? 147.851 120.996 162.874 1.00 35.86  ? 204 THR D O   1 
ATOM   9806  C CB  . THR D 1 204 ? 146.647 122.701 160.902 1.00 35.86  ? 204 THR D CB  1 
ATOM   9807  O OG1 . THR D 1 204 ? 145.971 121.805 160.013 1.00 35.86  ? 204 THR D OG1 1 
ATOM   9808  C CG2 . THR D 1 204 ? 146.453 124.126 160.422 1.00 35.86  ? 204 THR D CG2 1 
ATOM   9809  N N   . GLY D 1 205 ? 149.030 120.089 161.201 1.00 34.89  ? 205 GLY D N   1 
ATOM   9810  C CA  . GLY D 1 205 ? 149.314 118.881 161.943 1.00 34.89  ? 205 GLY D CA  1 
ATOM   9811  C C   . GLY D 1 205 ? 149.524 117.707 161.009 1.00 34.89  ? 205 GLY D C   1 
ATOM   9812  O O   . GLY D 1 205 ? 149.840 117.877 159.836 1.00 34.89  ? 205 GLY D O   1 
ATOM   9813  N N   . LYS D 1 206 ? 149.342 116.515 161.568 1.00 36.41  ? 206 LYS D N   1 
ATOM   9814  C CA  . LYS D 1 206 ? 149.525 115.247 160.866 1.00 36.41  ? 206 LYS D CA  1 
ATOM   9815  C C   . LYS D 1 206 ? 148.215 114.472 160.981 1.00 36.41  ? 206 LYS D C   1 
ATOM   9816  O O   . LYS D 1 206 ? 148.029 113.685 161.910 1.00 36.41  ? 206 LYS D O   1 
ATOM   9817  C CB  . LYS D 1 206 ? 150.701 114.478 161.460 1.00 36.41  ? 206 LYS D CB  1 
ATOM   9818  C CG  . LYS D 1 206 ? 151.018 113.162 160.778 1.00 36.41  ? 206 LYS D CG  1 
ATOM   9819  C CD  . LYS D 1 206 ? 152.358 112.622 161.248 1.00 36.41  ? 206 LYS D CD  1 
ATOM   9820  C CE  . LYS D 1 206 ? 152.529 111.158 160.886 1.00 36.41  ? 206 LYS D CE  1 
ATOM   9821  N NZ  . LYS D 1 206 ? 152.044 110.859 159.512 1.00 36.41  ? 206 LYS D NZ  1 
ATOM   9822  N N   . PHE D 1 207 ? 147.308 114.696 160.033 1.00 34.11  ? 207 PHE D N   1 
ATOM   9823  C CA  . PHE D 1 207 ? 145.966 114.136 160.119 1.00 34.11  ? 207 PHE D CA  1 
ATOM   9824  C C   . PHE D 1 207 ? 145.936 112.695 159.627 1.00 34.11  ? 207 PHE D C   1 
ATOM   9825  O O   . PHE D 1 207 ? 146.595 112.344 158.646 1.00 34.11  ? 207 PHE D O   1 
ATOM   9826  C CB  . PHE D 1 207 ? 144.987 114.976 159.303 1.00 34.11  ? 207 PHE D CB  1 
ATOM   9827  C CG  . PHE D 1 207 ? 144.642 116.289 159.935 1.00 34.11  ? 207 PHE D CG  1 
ATOM   9828  C CD1 . PHE D 1 207 ? 145.123 116.619 161.187 1.00 34.11  ? 207 PHE D CD1 1 
ATOM   9829  C CD2 . PHE D 1 207 ? 143.835 117.195 159.274 1.00 34.11  ? 207 PHE D CD2 1 
ATOM   9830  C CE1 . PHE D 1 207 ? 144.807 117.826 161.767 1.00 34.11  ? 207 PHE D CE1 1 
ATOM   9831  C CE2 . PHE D 1 207 ? 143.515 118.404 159.849 1.00 34.11  ? 207 PHE D CE2 1 
ATOM   9832  C CZ  . PHE D 1 207 ? 144.002 118.720 161.097 1.00 34.11  ? 207 PHE D CZ  1 
ATOM   9833  N N   . THR D 1 208 ? 145.158 111.863 160.315 1.00 31.07  ? 208 THR D N   1 
ATOM   9834  C CA  . THR D 1 208 ? 144.985 110.477 159.909 1.00 31.07  ? 208 THR D CA  1 
ATOM   9835  C C   . THR D 1 208 ? 144.109 110.390 158.665 1.00 31.07  ? 208 THR D C   1 
ATOM   9836  O O   . THR D 1 208 ? 143.346 111.303 158.347 1.00 31.07  ? 208 THR D O   1 
ATOM   9837  C CB  . THR D 1 208 ? 144.358 109.659 161.031 1.00 31.07  ? 208 THR D CB  1 
ATOM   9838  O OG1 . THR D 1 208 ? 143.875 108.420 160.502 1.00 31.07  ? 208 THR D OG1 1 
ATOM   9839  C CG2 . THR D 1 208 ? 143.204 110.418 161.646 1.00 31.07  ? 208 THR D CG2 1 
ATOM   9840  N N   . CYS D 1 209 ? 144.223 109.268 157.958 1.00 29.30  ? 209 CYS D N   1 
ATOM   9841  C CA  . CYS D 1 209 ? 143.482 109.078 156.720 1.00 29.30  ? 209 CYS D CA  1 
ATOM   9842  C C   . CYS D 1 209 ? 143.429 107.595 156.395 1.00 29.30  ? 209 CYS D C   1 
ATOM   9843  O O   . CYS D 1 209 ? 144.349 106.842 156.718 1.00 29.30  ? 209 CYS D O   1 
ATOM   9844  C CB  . CYS D 1 209 ? 144.120 109.859 155.569 1.00 29.30  ? 209 CYS D CB  1 
ATOM   9845  S SG  . CYS D 1 209 ? 143.321 109.675 153.967 1.00 29.30  ? 209 CYS D SG  1 
ATOM   9846  N N   . ILE D 1 210 ? 142.340 107.186 155.749 1.00 30.80  ? 210 ILE D N   1 
ATOM   9847  C CA  . ILE D 1 210 ? 142.101 105.791 155.396 1.00 30.80  ? 210 ILE D CA  1 
ATOM   9848  C C   . ILE D 1 210 ? 141.549 105.743 153.979 1.00 30.80  ? 210 ILE D C   1 
ATOM   9849  O O   . ILE D 1 210 ? 140.595 106.458 153.657 1.00 30.80  ? 210 ILE D O   1 
ATOM   9850  C CB  . ILE D 1 210 ? 141.127 105.118 156.380 1.00 30.80  ? 210 ILE D CB  1 
ATOM   9851  C CG1 . ILE D 1 210 ? 141.842 104.781 157.682 1.00 30.80  ? 210 ILE D CG1 1 
ATOM   9852  C CG2 . ILE D 1 210 ? 140.543 103.871 155.777 1.00 30.80  ? 210 ILE D CG2 1 
ATOM   9853  C CD1 . ILE D 1 210 ? 143.059 103.926 157.494 1.00 30.80  ? 210 ILE D CD1 1 
ATOM   9854  N N   . GLU D 1 211 ? 142.136 104.898 153.135 1.00 33.19  ? 211 GLU D N   1 
ATOM   9855  C CA  . GLU D 1 211 ? 141.778 104.842 151.726 1.00 33.19  ? 211 GLU D CA  1 
ATOM   9856  C C   . GLU D 1 211 ? 141.430 103.418 151.327 1.00 33.19  ? 211 GLU D C   1 
ATOM   9857  O O   . GLU D 1 211 ? 142.093 102.466 151.747 1.00 33.19  ? 211 GLU D O   1 
ATOM   9858  C CB  . GLU D 1 211 ? 142.921 105.359 150.848 1.00 33.19  ? 211 GLU D CB  1 
ATOM   9859  C CG  . GLU D 1 211 ? 142.626 105.332 149.360 1.00 33.19  ? 211 GLU D CG  1 
ATOM   9860  C CD  . GLU D 1 211 ? 143.670 106.068 148.546 1.00 33.19  ? 211 GLU D CD  1 
ATOM   9861  O OE1 . GLU D 1 211 ? 144.807 106.222 149.037 1.00 33.19  ? 211 GLU D OE1 1 
ATOM   9862  O OE2 . GLU D 1 211 ? 143.353 106.496 147.417 1.00 33.19  ? 211 GLU D OE2 1 
ATOM   9863  N N   . VAL D 1 212 ? 140.386 103.280 150.512 1.00 31.66  ? 212 VAL D N   1 
ATOM   9864  C CA  . VAL D 1 212 ? 139.997 102.006 149.920 1.00 31.66  ? 212 VAL D CA  1 
ATOM   9865  C C   . VAL D 1 212 ? 139.933 102.187 148.410 1.00 31.66  ? 212 VAL D C   1 
ATOM   9866  O O   . VAL D 1 212 ? 139.376 103.176 147.921 1.00 31.66  ? 212 VAL D O   1 
ATOM   9867  C CB  . VAL D 1 212 ? 138.652 101.500 150.477 1.00 31.66  ? 212 VAL D CB  1 
ATOM   9868  C CG1 . VAL D 1 212 ? 137.575 102.556 150.329 1.00 31.66  ? 212 VAL D CG1 1 
ATOM   9869  C CG2 . VAL D 1 212 ? 138.241 100.218 149.783 1.00 31.66  ? 212 VAL D CG2 1 
ATOM   9870  N N   . ARG D 1 213 ? 140.522 101.249 147.674 1.00 38.11  ? 213 ARG D N   1 
ATOM   9871  C CA  . ARG D 1 213 ? 140.620 101.337 146.223 1.00 38.11  ? 213 ARG D CA  1 
ATOM   9872  C C   . ARG D 1 213 ? 139.605 100.406 145.577 1.00 38.11  ? 213 ARG D C   1 
ATOM   9873  O O   . ARG D 1 213 ? 139.491 99.240  145.966 1.00 38.11  ? 213 ARG D O   1 
ATOM   9874  C CB  . ARG D 1 213 ? 142.027 100.979 145.745 1.00 38.11  ? 213 ARG D CB  1 
ATOM   9875  C CG  . ARG D 1 213 ? 143.151 101.630 146.527 1.00 38.11  ? 213 ARG D CG  1 
ATOM   9876  C CD  . ARG D 1 213 ? 143.387 103.049 146.059 1.00 38.11  ? 213 ARG D CD  1 
ATOM   9877  N NE  . ARG D 1 213 ? 143.601 103.117 144.619 1.00 38.11  ? 213 ARG D NE  1 
ATOM   9878  C CZ  . ARG D 1 213 ? 144.785 103.269 144.042 1.00 38.11  ? 213 ARG D CZ  1 
ATOM   9879  N NH1 . ARG D 1 213 ? 145.891 103.395 144.756 1.00 38.11  ? 213 ARG D NH1 1 
ATOM   9880  N NH2 . ARG D 1 213 ? 144.860 103.304 142.715 1.00 38.11  ? 213 ARG D NH2 1 
ATOM   9881  N N   . PHE D 1 214 ? 138.879 100.921 144.592 1.00 37.67  ? 214 PHE D N   1 
ATOM   9882  C CA  . PHE D 1 214 ? 137.936 100.137 143.808 1.00 37.67  ? 214 PHE D CA  1 
ATOM   9883  C C   . PHE D 1 214 ? 138.514 99.911  142.420 1.00 37.67  ? 214 PHE D C   1 
ATOM   9884  O O   . PHE D 1 214 ? 138.892 100.869 141.741 1.00 37.67  ? 214 PHE D O   1 
ATOM   9885  C CB  . PHE D 1 214 ? 136.587 100.846 143.698 1.00 37.67  ? 214 PHE D CB  1 
ATOM   9886  C CG  . PHE D 1 214 ? 135.766 100.774 144.942 1.00 37.67  ? 214 PHE D CG  1 
ATOM   9887  C CD1 . PHE D 1 214 ? 135.729 99.618  145.695 1.00 37.67  ? 214 PHE D CD1 1 
ATOM   9888  C CD2 . PHE D 1 214 ? 135.031 101.864 145.361 1.00 37.67  ? 214 PHE D CD2 1 
ATOM   9889  C CE1 . PHE D 1 214 ? 134.973 99.551  146.842 1.00 37.67  ? 214 PHE D CE1 1 
ATOM   9890  C CE2 . PHE D 1 214 ? 134.275 101.801 146.505 1.00 37.67  ? 214 PHE D CE2 1 
ATOM   9891  C CZ  . PHE D 1 214 ? 134.248 100.645 147.249 1.00 37.67  ? 214 PHE D CZ  1 
ATOM   9892  N N   . HIS D 1 215 ? 138.577 98.653  142.000 1.00 47.33  ? 215 HIS D N   1 
ATOM   9893  C CA  . HIS D 1 215 ? 139.052 98.301  140.668 1.00 47.33  ? 215 HIS D CA  1 
ATOM   9894  C C   . HIS D 1 215 ? 137.845 97.960  139.805 1.00 47.33  ? 215 HIS D C   1 
ATOM   9895  O O   . HIS D 1 215 ? 137.147 96.975  140.062 1.00 47.33  ? 215 HIS D O   1 
ATOM   9896  C CB  . HIS D 1 215 ? 140.035 97.135  140.728 1.00 47.33  ? 215 HIS D CB  1 
ATOM   9897  C CG  . HIS D 1 215 ? 141.338 97.477  141.377 1.00 47.33  ? 215 HIS D CG  1 
ATOM   9898  N ND1 . HIS D 1 215 ? 142.150 98.494  140.924 1.00 47.33  ? 215 HIS D ND1 1 
ATOM   9899  C CD2 . HIS D 1 215 ? 141.975 96.932  142.440 1.00 47.33  ? 215 HIS D CD2 1 
ATOM   9900  C CE1 . HIS D 1 215 ? 143.228 98.565  141.684 1.00 47.33  ? 215 HIS D CE1 1 
ATOM   9901  N NE2 . HIS D 1 215 ? 143.147 97.628  142.611 1.00 47.33  ? 215 HIS D NE2 1 
ATOM   9902  N N   . LEU D 1 216 ? 137.601 98.774  138.783 1.00 47.55  ? 216 LEU D N   1 
ATOM   9903  C CA  . LEU D 1 216 ? 136.486 98.583  137.869 1.00 47.55  ? 216 LEU D CA  1 
ATOM   9904  C C   . LEU D 1 216 ? 137.024 98.318  136.472 1.00 47.55  ? 216 LEU D C   1 
ATOM   9905  O O   . LEU D 1 216 ? 137.810 99.113  135.947 1.00 47.55  ? 216 LEU D O   1 
ATOM   9906  C CB  . LEU D 1 216 ? 135.570 99.808  137.848 1.00 47.55  ? 216 LEU D CB  1 
ATOM   9907  C CG  . LEU D 1 216 ? 134.767 100.116 139.109 1.00 47.55  ? 216 LEU D CG  1 
ATOM   9908  C CD1 . LEU D 1 216 ? 135.552 101.025 140.033 1.00 47.55  ? 216 LEU D CD1 1 
ATOM   9909  C CD2 . LEU D 1 216 ? 133.444 100.751 138.739 1.00 47.55  ? 216 LEU D CD2 1 
ATOM   9910  N N   . GLU D 1 217 ? 136.599 97.212  135.872 1.00 55.09  ? 217 GLU D N   1 
ATOM   9911  C CA  . GLU D 1 217 ? 136.919 96.908  134.487 1.00 55.09  ? 217 GLU D CA  1 
ATOM   9912  C C   . GLU D 1 217 ? 135.670 97.089  133.640 1.00 55.09  ? 217 GLU D C   1 
ATOM   9913  O O   . GLU D 1 217 ? 134.567 96.717  134.052 1.00 55.09  ? 217 GLU D O   1 
ATOM   9914  C CB  . GLU D 1 217 ? 137.480 95.491  134.333 1.00 55.09  ? 217 GLU D CB  1 
ATOM   9915  C CG  . GLU D 1 217 ? 136.561 94.378  134.788 1.00 55.09  ? 217 GLU D CG  1 
ATOM   9916  C CD  . GLU D 1 217 ? 137.291 93.057  134.938 1.00 55.09  ? 217 GLU D CD  1 
ATOM   9917  O OE1 . GLU D 1 217 ? 138.526 93.079  135.118 1.00 55.09  ? 217 GLU D OE1 1 
ATOM   9918  O OE2 . GLU D 1 217 ? 136.633 91.997  134.873 1.00 55.09  ? 217 GLU D OE2 1 
ATOM   9919  N N   . ARG D 1 218 ? 135.848 97.675  132.463 1.00 52.41  ? 218 ARG D N   1 
ATOM   9920  C CA  . ARG D 1 218 ? 134.744 98.144  131.640 1.00 52.41  ? 218 ARG D CA  1 
ATOM   9921  C C   . ARG D 1 218 ? 134.399 97.111  130.578 1.00 52.41  ? 218 ARG D C   1 
ATOM   9922  O O   . ARG D 1 218 ? 135.288 96.598  129.893 1.00 52.41  ? 218 ARG D O   1 
ATOM   9923  C CB  . ARG D 1 218 ? 135.108 99.475  130.984 1.00 52.41  ? 218 ARG D CB  1 
ATOM   9924  C CG  . ARG D 1 218 ? 134.118 99.953  129.955 1.00 52.41  ? 218 ARG D CG  1 
ATOM   9925  C CD  . ARG D 1 218 ? 134.448 101.361 129.514 1.00 52.41  ? 218 ARG D CD  1 
ATOM   9926  N NE  . ARG D 1 218 ? 134.450 102.322 130.608 1.00 52.41  ? 218 ARG D NE  1 
ATOM   9927  C CZ  . ARG D 1 218 ? 134.411 103.636 130.436 1.00 52.41  ? 218 ARG D CZ  1 
ATOM   9928  N NH1 . ARG D 1 218 ? 134.358 104.172 129.229 1.00 52.41  ? 218 ARG D NH1 1 
ATOM   9929  N NH2 . ARG D 1 218 ? 134.426 104.431 131.501 1.00 52.41  ? 218 ARG D NH2 1 
ATOM   9930  N N   . GLN D 1 219 ? 133.109 96.810  130.445 1.00 57.20  ? 219 GLN D N   1 
ATOM   9931  C CA  . GLN D 1 219 ? 132.643 95.910  129.400 1.00 57.20  ? 219 GLN D CA  1 
ATOM   9932  C C   . GLN D 1 219 ? 132.462 96.686  128.102 1.00 57.20  ? 219 GLN D C   1 
ATOM   9933  O O   . GLN D 1 219 ? 131.842 97.752  128.088 1.00 57.20  ? 219 GLN D O   1 
ATOM   9934  C CB  . GLN D 1 219 ? 131.334 95.241  129.811 1.00 57.20  ? 219 GLN D CB  1 
ATOM   9935  C CG  . GLN D 1 219 ? 130.554 96.006  130.858 1.00 57.20  ? 219 GLN D CG  1 
ATOM   9936  C CD  . GLN D 1 219 ? 129.284 95.294  131.269 1.00 57.20  ? 219 GLN D CD  1 
ATOM   9937  O OE1 . GLN D 1 219 ? 129.034 94.161  130.861 1.00 57.20  ? 219 GLN D OE1 1 
ATOM   9938  N NE2 . GLN D 1 219 ? 128.471 95.958  132.081 1.00 57.20  ? 219 GLN D NE2 1 
ATOM   9939  N N   . MET D 1 220 ? 132.999 96.143  127.010 1.00 65.08  ? 220 MET D N   1 
ATOM   9940  C CA  . MET D 1 220 ? 133.099 96.851  125.741 1.00 65.08  ? 220 MET D CA  1 
ATOM   9941  C C   . MET D 1 220 ? 131.998 96.469  124.759 1.00 65.08  ? 220 MET D C   1 
ATOM   9942  O O   . MET D 1 220 ? 132.146 96.707  123.556 1.00 65.08  ? 220 MET D O   1 
ATOM   9943  C CB  . MET D 1 220 ? 134.464 96.597  125.106 1.00 65.08  ? 220 MET D CB  1 
ATOM   9944  C CG  . MET D 1 220 ? 134.829 95.127  125.038 1.00 65.08  ? 220 MET D CG  1 
ATOM   9945  S SD  . MET D 1 220 ? 136.382 94.805  124.185 1.00 65.08  ? 220 MET D SD  1 
ATOM   9946  C CE  . MET D 1 220 ? 136.387 93.014  124.181 1.00 65.08  ? 220 MET D CE  1 
ATOM   9947  N N   . GLY D 1 221 ? 130.905 95.874  125.238 1.00 61.74  ? 221 GLY D N   1 
ATOM   9948  C CA  . GLY D 1 221 ? 129.874 95.411  124.322 1.00 61.74  ? 221 GLY D CA  1 
ATOM   9949  C C   . GLY D 1 221 ? 129.229 96.539  123.540 1.00 61.74  ? 221 GLY D C   1 
ATOM   9950  O O   . GLY D 1 221 ? 129.090 96.464  122.315 1.00 61.74  ? 221 GLY D O   1 
ATOM   9951  N N   . TYR D 1 222 ? 128.842 97.610  124.234 1.00 66.08  ? 222 TYR D N   1 
ATOM   9952  C CA  . TYR D 1 222 ? 128.124 98.693  123.569 1.00 66.08  ? 222 TYR D CA  1 
ATOM   9953  C C   . TYR D 1 222 ? 129.035 99.443  122.608 1.00 66.08  ? 222 TYR D C   1 
ATOM   9954  O O   . TYR D 1 222 ? 128.643 99.739  121.475 1.00 66.08  ? 222 TYR D O   1 
ATOM   9955  C CB  . TYR D 1 222 ? 127.504 99.632  124.611 1.00 66.08  ? 222 TYR D CB  1 
ATOM   9956  C CG  . TYR D 1 222 ? 127.117 101.025 124.134 1.00 66.08  ? 222 TYR D CG  1 
ATOM   9957  C CD1 . TYR D 1 222 ? 128.071 102.003 123.883 1.00 66.08  ? 222 TYR D CD1 1 
ATOM   9958  C CD2 . TYR D 1 222 ? 125.783 101.354 123.937 1.00 66.08  ? 222 TYR D CD2 1 
ATOM   9959  C CE1 . TYR D 1 222 ? 127.711 103.262 123.454 1.00 66.08  ? 222 TYR D CE1 1 
ATOM   9960  C CE2 . TYR D 1 222 ? 125.413 102.614 123.506 1.00 66.08  ? 222 TYR D CE2 1 
ATOM   9961  C CZ  . TYR D 1 222 ? 126.381 103.564 123.267 1.00 66.08  ? 222 TYR D CZ  1 
ATOM   9962  O OH  . TYR D 1 222 ? 126.022 104.820 122.837 1.00 66.08  ? 222 TYR D OH  1 
ATOM   9963  N N   . TYR D 1 223 ? 130.248 99.783  123.050 1.00 63.81  ? 223 TYR D N   1 
ATOM   9964  C CA  . TYR D 1 223 ? 131.180 100.471 122.164 1.00 63.81  ? 223 TYR D CA  1 
ATOM   9965  C C   . TYR D 1 223 ? 131.435 99.650  120.912 1.00 63.81  ? 223 TYR D C   1 
ATOM   9966  O O   . TYR D 1 223 ? 131.347 100.166 119.793 1.00 63.81  ? 223 TYR D O   1 
ATOM   9967  C CB  . TYR D 1 223 ? 132.497 100.766 122.882 1.00 63.81  ? 223 TYR D CB  1 
ATOM   9968  C CG  . TYR D 1 223 ? 132.362 101.364 124.260 1.00 63.81  ? 223 TYR D CG  1 
ATOM   9969  C CD1 . TYR D 1 223 ? 131.283 102.167 124.595 1.00 63.81  ? 223 TYR D CD1 1 
ATOM   9970  C CD2 . TYR D 1 223 ? 133.317 101.121 125.228 1.00 63.81  ? 223 TYR D CD2 1 
ATOM   9971  C CE1 . TYR D 1 223 ? 131.161 102.711 125.854 1.00 63.81  ? 223 TYR D CE1 1 
ATOM   9972  C CE2 . TYR D 1 223 ? 133.206 101.659 126.484 1.00 63.81  ? 223 TYR D CE2 1 
ATOM   9973  C CZ  . TYR D 1 223 ? 132.127 102.452 126.797 1.00 63.81  ? 223 TYR D CZ  1 
ATOM   9974  O OH  . TYR D 1 223 ? 132.022 102.986 128.060 1.00 63.81  ? 223 TYR D OH  1 
ATOM   9975  N N   . LEU D 1 224 ? 131.720 98.358  121.083 1.00 66.01  ? 224 LEU D N   1 
ATOM   9976  C CA  . LEU D 1 224 ? 131.925 97.483  119.935 1.00 66.01  ? 224 LEU D CA  1 
ATOM   9977  C C   . LEU D 1 224 ? 130.727 97.535  118.996 1.00 66.01  ? 224 LEU D C   1 
ATOM   9978  O O   . LEU D 1 224 ? 130.836 98.023  117.866 1.00 66.01  ? 224 LEU D O   1 
ATOM   9979  C CB  . LEU D 1 224 ? 132.184 96.052  120.408 1.00 66.01  ? 224 LEU D CB  1 
ATOM   9980  C CG  . LEU D 1 224 ? 132.508 95.024  119.325 1.00 66.01  ? 224 LEU D CG  1 
ATOM   9981  C CD1 . LEU D 1 224 ? 133.703 94.184  119.735 1.00 66.01  ? 224 LEU D CD1 1 
ATOM   9982  C CD2 . LEU D 1 224 ? 131.304 94.139  119.053 1.00 66.01  ? 224 LEU D CD2 1 
ATOM   9983  N N   . ILE D 1 225 ? 129.557 97.121  119.492 1.00 66.44  ? 225 ILE D N   1 
ATOM   9984  C CA  . ILE D 1 225 ? 128.383 96.957  118.638 1.00 66.44  ? 225 ILE D CA  1 
ATOM   9985  C C   . ILE D 1 225 ? 128.017 98.266  117.949 1.00 66.44  ? 225 ILE D C   1 
ATOM   9986  O O   . ILE D 1 225 ? 127.727 98.288  116.746 1.00 66.44  ? 225 ILE D O   1 
ATOM   9987  C CB  . ILE D 1 225 ? 127.205 96.406  119.464 1.00 66.44  ? 225 ILE D CB  1 
ATOM   9988  C CG1 . ILE D 1 225 ? 127.431 94.932  119.800 1.00 66.44  ? 225 ILE D CG1 1 
ATOM   9989  C CG2 . ILE D 1 225 ? 125.894 96.587  118.719 1.00 66.44  ? 225 ILE D CG2 1 
ATOM   9990  C CD1 . ILE D 1 225 ? 126.322 94.321  120.625 1.00 66.44  ? 225 ILE D CD1 1 
ATOM   9991  N N   . GLN D 1 226 ? 128.033 99.377  118.684 1.00 72.04  ? 226 GLN D N   1 
ATOM   9992  C CA  . GLN D 1 226 ? 127.535 100.632 118.141 1.00 72.04  ? 226 GLN D CA  1 
ATOM   9993  C C   . GLN D 1 226 ? 128.585 101.426 117.375 1.00 72.04  ? 226 GLN D C   1 
ATOM   9994  O O   . GLN D 1 226 ? 128.220 102.383 116.683 1.00 72.04  ? 226 GLN D O   1 
ATOM   9995  C CB  . GLN D 1 226 ? 126.970 101.501 119.267 1.00 72.04  ? 226 GLN D CB  1 
ATOM   9996  C CG  . GLN D 1 226 ? 125.786 100.886 120.001 1.00 72.04  ? 226 GLN D CG  1 
ATOM   9997  C CD  . GLN D 1 226 ? 124.602 100.625 119.092 1.00 72.04  ? 226 GLN D CD  1 
ATOM   9998  O OE1 . GLN D 1 226 ? 124.440 99.524  118.565 1.00 72.04  ? 226 GLN D OE1 1 
ATOM   9999  N NE2 . GLN D 1 226 ? 123.765 101.638 118.905 1.00 72.04  ? 226 GLN D NE2 1 
ATOM   10000 N N   . MET D 1 227 ? 129.867 101.081 117.476 1.00 71.69  ? 227 MET D N   1 
ATOM   10001 C CA  . MET D 1 227 ? 130.809 101.952 116.788 1.00 71.69  ? 227 MET D CA  1 
ATOM   10002 C C   . MET D 1 227 ? 131.805 101.207 115.912 1.00 71.69  ? 227 MET D C   1 
ATOM   10003 O O   . MET D 1 227 ? 132.132 101.689 114.825 1.00 71.69  ? 227 MET D O   1 
ATOM   10004 C CB  . MET D 1 227 ? 131.545 102.798 117.833 1.00 71.69  ? 227 MET D CB  1 
ATOM   10005 C CG  . MET D 1 227 ? 130.710 103.961 118.336 1.00 71.69  ? 227 MET D CG  1 
ATOM   10006 S SD  . MET D 1 227 ? 131.572 105.076 119.455 1.00 71.69  ? 227 MET D SD  1 
ATOM   10007 C CE  . MET D 1 227 ? 130.572 106.547 119.261 1.00 71.69  ? 227 MET D CE  1 
ATOM   10008 N N   . TYR D 1 228 ? 132.297 100.045 116.350 1.00 65.61  ? 228 TYR D N   1 
ATOM   10009 C CA  . TYR D 1 228 ? 133.319 99.353  115.574 1.00 65.61  ? 228 TYR D CA  1 
ATOM   10010 C C   . TYR D 1 228 ? 132.721 98.709  114.331 1.00 65.61  ? 228 TYR D C   1 
ATOM   10011 O O   . TYR D 1 228 ? 133.299 98.794  113.242 1.00 65.61  ? 228 TYR D O   1 
ATOM   10012 C CB  . TYR D 1 228 ? 134.012 98.305  116.441 1.00 65.61  ? 228 TYR D CB  1 
ATOM   10013 C CG  . TYR D 1 228 ? 135.013 98.875  117.418 1.00 65.61  ? 228 TYR D CG  1 
ATOM   10014 C CD1 . TYR D 1 228 ? 134.596 99.583  118.534 1.00 65.61  ? 228 TYR D CD1 1 
ATOM   10015 C CD2 . TYR D 1 228 ? 136.376 98.699  117.229 1.00 65.61  ? 228 TYR D CD2 1 
ATOM   10016 C CE1 . TYR D 1 228 ? 135.505 100.103 119.431 1.00 65.61  ? 228 TYR D CE1 1 
ATOM   10017 C CE2 . TYR D 1 228 ? 137.292 99.215  118.121 1.00 65.61  ? 228 TYR D CE2 1 
ATOM   10018 C CZ  . TYR D 1 228 ? 136.851 99.916  119.220 1.00 65.61  ? 228 TYR D CZ  1 
ATOM   10019 O OH  . TYR D 1 228 ? 137.759 100.432 120.111 1.00 65.61  ? 228 TYR D OH  1 
ATOM   10020 N N   . ILE D 1 229 ? 131.567 98.056  114.479 1.00 68.90  ? 229 ILE D N   1 
ATOM   10021 C CA  . ILE D 1 229 ? 130.922 97.416  113.332 1.00 68.90  ? 229 ILE D CA  1 
ATOM   10022 C C   . ILE D 1 229 ? 130.573 98.419  112.237 1.00 68.90  ? 229 ILE D C   1 
ATOM   10023 O O   . ILE D 1 229 ? 130.822 98.121  111.056 1.00 68.90  ? 229 ILE D O   1 
ATOM   10024 C CB  . ILE D 1 229 ? 129.707 96.596  113.800 1.00 68.90  ? 229 ILE D CB  1 
ATOM   10025 C CG1 . ILE D 1 229 ? 130.157 95.435  114.691 1.00 68.90  ? 229 ILE D CG1 1 
ATOM   10026 C CG2 . ILE D 1 229 ? 128.908 96.086  112.612 1.00 68.90  ? 229 ILE D CG2 1 
ATOM   10027 C CD1 . ILE D 1 229 ? 131.343 94.667  114.148 1.00 68.90  ? 229 ILE D CD1 1 
ATOM   10028 N N   . PRO D 1 230 ? 129.990 99.590  112.532 1.00 70.69  ? 230 PRO D N   1 
ATOM   10029 C CA  . PRO D 1 230 ? 129.752 100.558 111.447 1.00 70.69  ? 230 PRO D CA  1 
ATOM   10030 C C   . PRO D 1 230 ? 131.012 100.959 110.702 1.00 70.69  ? 230 PRO D C   1 
ATOM   10031 O O   . PRO D 1 230 ? 130.968 101.118 109.478 1.00 70.69  ? 230 PRO D O   1 
ATOM   10032 C CB  . PRO D 1 230 ? 129.119 101.747 112.179 1.00 70.69  ? 230 PRO D CB  1 
ATOM   10033 C CG  . PRO D 1 230 ? 128.441 101.138 113.341 1.00 70.69  ? 230 PRO D CG  1 
ATOM   10034 C CD  . PRO D 1 230 ? 129.343 100.024 113.785 1.00 70.69  ? 230 PRO D CD  1 
ATOM   10035 N N   . SER D 1 231 ? 132.141 101.117 111.398 1.00 70.33  ? 231 SER D N   1 
ATOM   10036 C CA  . SER D 1 231 ? 133.380 101.477 110.714 1.00 70.33  ? 231 SER D CA  1 
ATOM   10037 C C   . SER D 1 231 ? 133.841 100.367 109.775 1.00 70.33  ? 231 SER D C   1 
ATOM   10038 O O   . SER D 1 231 ? 134.284 100.639 108.650 1.00 70.33  ? 231 SER D O   1 
ATOM   10039 C CB  . SER D 1 231 ? 134.466 101.802 111.737 1.00 70.33  ? 231 SER D CB  1 
ATOM   10040 O OG  . SER D 1 231 ? 134.560 100.785 112.718 1.00 70.33  ? 231 SER D OG  1 
ATOM   10041 N N   . LEU D 1 232 ? 133.753 99.113  110.223 1.00 71.69  ? 232 LEU D N   1 
ATOM   10042 C CA  . LEU D 1 232 ? 134.125 97.993  109.365 1.00 71.69  ? 232 LEU D CA  1 
ATOM   10043 C C   . LEU D 1 232 ? 133.219 97.916  108.143 1.00 71.69  ? 232 LEU D C   1 
ATOM   10044 O O   . LEU D 1 232 ? 133.693 97.701  107.019 1.00 71.69  ? 232 LEU D O   1 
ATOM   10045 C CB  . LEU D 1 232 ? 134.076 96.689  110.160 1.00 71.69  ? 232 LEU D CB  1 
ATOM   10046 C CG  . LEU D 1 232 ? 134.219 95.382  109.378 1.00 71.69  ? 232 LEU D CG  1 
ATOM   10047 C CD1 . LEU D 1 232 ? 135.247 94.480  110.039 1.00 71.69  ? 232 LEU D CD1 1 
ATOM   10048 C CD2 . LEU D 1 232 ? 132.878 94.672  109.265 1.00 71.69  ? 232 LEU D CD2 1 
ATOM   10049 N N   . LEU D 1 233 ? 131.912 98.100  108.339 1.00 73.89  ? 233 LEU D N   1 
ATOM   10050 C CA  . LEU D 1 233 ? 130.998 98.103  107.203 1.00 73.89  ? 233 LEU D CA  1 
ATOM   10051 C C   . LEU D 1 233 ? 131.319 99.245  106.248 1.00 73.89  ? 233 LEU D C   1 
ATOM   10052 O O   . LEU D 1 233 ? 131.253 99.080  105.025 1.00 73.89  ? 233 LEU D O   1 
ATOM   10053 C CB  . LEU D 1 233 ? 129.552 98.199  107.687 1.00 73.89  ? 233 LEU D CB  1 
ATOM   10054 C CG  . LEU D 1 233 ? 128.946 96.924  108.274 1.00 73.89  ? 233 LEU D CG  1 
ATOM   10055 C CD1 . LEU D 1 233 ? 127.427 97.013  108.277 1.00 73.89  ? 233 LEU D CD1 1 
ATOM   10056 C CD2 . LEU D 1 233 ? 129.417 95.695  107.510 1.00 73.89  ? 233 LEU D CD2 1 
ATOM   10057 N N   . ILE D 1 234 ? 131.681 100.409 106.790 1.00 76.57  ? 234 ILE D N   1 
ATOM   10058 C CA  . ILE D 1 234 ? 131.985 101.567 105.957 1.00 76.57  ? 234 ILE D CA  1 
ATOM   10059 C C   . ILE D 1 234 ? 133.218 101.302 105.101 1.00 76.57  ? 234 ILE D C   1 
ATOM   10060 O O   . ILE D 1 234 ? 133.231 101.585 103.898 1.00 76.57  ? 234 ILE D O   1 
ATOM   10061 C CB  . ILE D 1 234 ? 132.160 102.820 106.833 1.00 76.57  ? 234 ILE D CB  1 
ATOM   10062 C CG1 . ILE D 1 234 ? 130.796 103.382 107.234 1.00 76.57  ? 234 ILE D CG1 1 
ATOM   10063 C CG2 . ILE D 1 234 ? 132.982 103.870 106.116 1.00 76.57  ? 234 ILE D CG2 1 
ATOM   10064 C CD1 . ILE D 1 234 ? 129.836 103.526 106.081 1.00 76.57  ? 234 ILE D CD1 1 
ATOM   10065 N N   . VAL D 1 235 ? 134.275 100.751 105.704 1.00 79.14  ? 235 VAL D N   1 
ATOM   10066 C CA  . VAL D 1 235 ? 135.493 100.512 104.931 1.00 79.14  ? 235 VAL D CA  1 
ATOM   10067 C C   . VAL D 1 235 ? 135.273 99.394  103.912 1.00 79.14  ? 235 VAL D C   1 
ATOM   10068 O O   . VAL D 1 235 ? 135.807 99.439  102.794 1.00 79.14  ? 235 VAL D O   1 
ATOM   10069 C CB  . VAL D 1 235 ? 136.692 100.231 105.859 1.00 79.14  ? 235 VAL D CB  1 
ATOM   10070 C CG1 . VAL D 1 235 ? 136.406 99.088  106.804 1.00 79.14  ? 235 VAL D CG1 1 
ATOM   10071 C CG2 . VAL D 1 235 ? 137.954 99.965  105.048 1.00 79.14  ? 235 VAL D CG2 1 
ATOM   10072 N N   . ILE D 1 236 ? 134.472 98.383  104.266 1.00 81.45  ? 236 ILE D N   1 
ATOM   10073 C CA  . ILE D 1 236 ? 134.145 97.332  103.304 1.00 81.45  ? 236 ILE D CA  1 
ATOM   10074 C C   . ILE D 1 236 ? 133.380 97.913  102.119 1.00 81.45  ? 236 ILE D C   1 
ATOM   10075 O O   . ILE D 1 236 ? 133.656 97.583  100.957 1.00 81.45  ? 236 ILE D O   1 
ATOM   10076 C CB  . ILE D 1 236 ? 133.355 96.206  103.996 1.00 81.45  ? 236 ILE D CB  1 
ATOM   10077 C CG1 . ILE D 1 236 ? 134.293 95.330  104.829 1.00 81.45  ? 236 ILE D CG1 1 
ATOM   10078 C CG2 . ILE D 1 236 ? 132.594 95.370  102.975 1.00 81.45  ? 236 ILE D CG2 1 
ATOM   10079 C CD1 . ILE D 1 236 ? 135.028 94.282  104.026 1.00 81.45  ? 236 ILE D CD1 1 
ATOM   10080 N N   . LEU D 1 237 ? 132.407 98.785  102.394 1.00 81.89  ? 237 LEU D N   1 
ATOM   10081 C CA  . LEU D 1 237 ? 131.670 99.440  101.320 1.00 81.89  ? 237 LEU D CA  1 
ATOM   10082 C C   . LEU D 1 237 ? 132.592 100.308 100.475 1.00 81.89  ? 237 LEU D C   1 
ATOM   10083 O O   . LEU D 1 237 ? 132.413 100.413 99.258  1.00 81.89  ? 237 LEU D O   1 
ATOM   10084 C CB  . LEU D 1 237 ? 130.525 100.271 101.902 1.00 81.89  ? 237 LEU D CB  1 
ATOM   10085 C CG  . LEU D 1 237 ? 129.608 101.011 100.926 1.00 81.89  ? 237 LEU D CG  1 
ATOM   10086 C CD1 . LEU D 1 237 ? 128.151 100.820 101.314 1.00 81.89  ? 237 LEU D CD1 1 
ATOM   10087 C CD2 . LEU D 1 237 ? 129.954 102.492 100.877 1.00 81.89  ? 237 LEU D CD2 1 
ATOM   10088 N N   . SER D 1 238 ? 133.581 100.943 101.106 1.00 83.95  ? 238 SER D N   1 
ATOM   10089 C CA  . SER D 1 238 ? 134.551 101.729 100.352 1.00 83.95  ? 238 SER D CA  1 
ATOM   10090 C C   . SER D 1 238 ? 135.341 100.850 99.391  1.00 83.95  ? 238 SER D C   1 
ATOM   10091 O O   . SER D 1 238 ? 135.545 101.216 98.227  1.00 83.95  ? 238 SER D O   1 
ATOM   10092 C CB  . SER D 1 238 ? 135.495 102.457 101.308 1.00 83.95  ? 238 SER D CB  1 
ATOM   10093 O OG  . SER D 1 238 ? 136.386 101.549 101.930 1.00 83.95  ? 238 SER D OG  1 
ATOM   10094 N N   . TRP D 1 239 ? 135.787 99.683  99.860  1.00 86.49  ? 239 TRP D N   1 
ATOM   10095 C CA  . TRP D 1 239 ? 136.492 98.755  98.978  1.00 86.49  ? 239 TRP D CA  1 
ATOM   10096 C C   . TRP D 1 239 ? 135.601 98.318  97.822  1.00 86.49  ? 239 TRP D C   1 
ATOM   10097 O O   . TRP D 1 239 ? 136.031 98.290  96.661  1.00 86.49  ? 239 TRP D O   1 
ATOM   10098 C CB  . TRP D 1 239 ? 136.964 97.530  99.760  1.00 86.49  ? 239 TRP D CB  1 
ATOM   10099 C CG  . TRP D 1 239 ? 137.937 97.821  100.842 1.00 86.49  ? 239 TRP D CG  1 
ATOM   10100 C CD1 . TRP D 1 239 ? 138.688 98.948  100.994 1.00 86.49  ? 239 TRP D CD1 1 
ATOM   10101 C CD2 . TRP D 1 239 ? 138.272 96.963  101.934 1.00 86.49  ? 239 TRP D CD2 1 
ATOM   10102 N NE1 . TRP D 1 239 ? 139.470 98.845  102.118 1.00 86.49  ? 239 TRP D NE1 1 
ATOM   10103 C CE2 . TRP D 1 239 ? 139.232 97.634  102.712 1.00 86.49  ? 239 TRP D CE2 1 
ATOM   10104 C CE3 . TRP D 1 239 ? 137.851 95.690  102.330 1.00 86.49  ? 239 TRP D CE3 1 
ATOM   10105 C CZ2 . TRP D 1 239 ? 139.778 97.077  103.863 1.00 86.49  ? 239 TRP D CZ2 1 
ATOM   10106 C CZ3 . TRP D 1 239 ? 138.395 95.138  103.472 1.00 86.49  ? 239 TRP D CZ3 1 
ATOM   10107 C CH2 . TRP D 1 239 ? 139.347 95.830  104.226 1.00 86.49  ? 239 TRP D CH2 1 
ATOM   10108 N N   . VAL D 1 240 ? 134.348 97.971  98.128  1.00 85.61  ? 240 VAL D N   1 
ATOM   10109 C CA  . VAL D 1 240 ? 133.430 97.495  97.096  1.00 85.61  ? 240 VAL D CA  1 
ATOM   10110 C C   . VAL D 1 240 ? 133.185 98.582  96.058  1.00 85.61  ? 240 VAL D C   1 
ATOM   10111 O O   . VAL D 1 240 ? 133.166 98.316  94.850  1.00 85.61  ? 240 VAL D O   1 
ATOM   10112 C CB  . VAL D 1 240 ? 132.117 97.008  97.734  1.00 85.61  ? 240 VAL D CB  1 
ATOM   10113 C CG1 . VAL D 1 240 ? 131.069 96.747  96.665  1.00 85.61  ? 240 VAL D CG1 1 
ATOM   10114 C CG2 . VAL D 1 240 ? 132.366 95.755  98.557  1.00 85.61  ? 240 VAL D CG2 1 
ATOM   10115 N N   . SER D 1 241 ? 132.998 99.822  96.511  1.00 91.15  ? 241 SER D N   1 
ATOM   10116 C CA  . SER D 1 241 ? 132.826 100.934 95.584  1.00 91.15  ? 241 SER D CA  1 
ATOM   10117 C C   . SER D 1 241 ? 134.068 101.131 94.727  1.00 91.15  ? 241 SER D C   1 
ATOM   10118 O O   . SER D 1 241 ? 133.966 101.362 93.518  1.00 91.15  ? 241 SER D O   1 
ATOM   10119 C CB  . SER D 1 241 ? 132.500 102.213 96.357  1.00 91.15  ? 241 SER D CB  1 
ATOM   10120 O OG  . SER D 1 241 ? 132.783 103.366 95.583  1.00 91.15  ? 241 SER D OG  1 
ATOM   10121 N N   . PHE D 1 242 ? 135.253 101.037 95.335  1.00 96.83  ? 242 PHE D N   1 
ATOM   10122 C CA  . PHE D 1 242 ? 136.483 101.242 94.581  1.00 96.83  ? 242 PHE D CA  1 
ATOM   10123 C C   . PHE D 1 242 ? 136.714 100.137 93.556  1.00 96.83  ? 242 PHE D C   1 
ATOM   10124 O O   . PHE D 1 242 ? 137.375 100.369 92.538  1.00 96.83  ? 242 PHE D O   1 
ATOM   10125 C CB  . PHE D 1 242 ? 137.668 101.351 95.543  1.00 96.83  ? 242 PHE D CB  1 
ATOM   10126 C CG  . PHE D 1 242 ? 138.937 100.752 95.016  1.00 96.83  ? 242 PHE D CG  1 
ATOM   10127 C CD1 . PHE D 1 242 ? 139.815 101.514 94.266  1.00 96.83  ? 242 PHE D CD1 1 
ATOM   10128 C CD2 . PHE D 1 242 ? 139.264 99.436  95.291  1.00 96.83  ? 242 PHE D CD2 1 
ATOM   10129 C CE1 . PHE D 1 242 ? 140.984 100.968 93.782  1.00 96.83  ? 242 PHE D CE1 1 
ATOM   10130 C CE2 . PHE D 1 242 ? 140.429 98.887  94.810  1.00 96.83  ? 242 PHE D CE2 1 
ATOM   10131 C CZ  . PHE D 1 242 ? 141.292 99.652  94.057  1.00 96.83  ? 242 PHE D CZ  1 
ATOM   10132 N N   . TRP D 1 243 ? 136.181 98.937  93.802  1.00 103.28 ? 243 TRP D N   1 
ATOM   10133 C CA  . TRP D 1 243 ? 136.390 97.832  92.869  1.00 103.28 ? 243 TRP D CA  1 
ATOM   10134 C C   . TRP D 1 243 ? 135.789 98.097  91.492  1.00 103.28 ? 243 TRP D C   1 
ATOM   10135 O O   . TRP D 1 243 ? 136.195 97.453  90.519  1.00 103.28 ? 243 TRP D O   1 
ATOM   10136 C CB  . TRP D 1 243 ? 135.807 96.537  93.439  1.00 103.28 ? 243 TRP D CB  1 
ATOM   10137 C CG  . TRP D 1 243 ? 136.841 95.506  93.783  1.00 103.28 ? 243 TRP D CG  1 
ATOM   10138 C CD1 . TRP D 1 243 ? 137.052 94.936  95.003  1.00 103.28 ? 243 TRP D CD1 1 
ATOM   10139 C CD2 . TRP D 1 243 ? 137.809 94.928  92.898  1.00 103.28 ? 243 TRP D CD2 1 
ATOM   10140 N NE1 . TRP D 1 243 ? 138.086 94.035  94.933  1.00 103.28 ? 243 TRP D NE1 1 
ATOM   10141 C CE2 . TRP D 1 243 ? 138.568 94.012  93.652  1.00 103.28 ? 243 TRP D CE2 1 
ATOM   10142 C CE3 . TRP D 1 243 ? 138.105 95.093  91.542  1.00 103.28 ? 243 TRP D CE3 1 
ATOM   10143 C CZ2 . TRP D 1 243 ? 139.604 93.265  93.095  1.00 103.28 ? 243 TRP D CZ2 1 
ATOM   10144 C CZ3 . TRP D 1 243 ? 139.135 94.352  90.992  1.00 103.28 ? 243 TRP D CZ3 1 
ATOM   10145 C CH2 . TRP D 1 243 ? 139.872 93.450  91.768  1.00 103.28 ? 243 TRP D CH2 1 
ATOM   10146 N N   . ILE D 1 244 ? 134.833 99.023  91.386  1.00 101.78 ? 244 ILE D N   1 
ATOM   10147 C CA  . ILE D 1 244 ? 134.216 99.321  90.098  1.00 101.78 ? 244 ILE D CA  1 
ATOM   10148 C C   . ILE D 1 244 ? 135.232 99.990  89.179  1.00 101.78 ? 244 ILE D C   1 
ATOM   10149 O O   . ILE D 1 244 ? 136.190 100.632 89.631  1.00 101.78 ? 244 ILE D O   1 
ATOM   10150 C CB  . ILE D 1 244 ? 132.968 100.203 90.293  1.00 101.78 ? 244 ILE D CB  1 
ATOM   10151 C CG1 . ILE D 1 244 ? 132.138 99.699  91.473  1.00 101.78 ? 244 ILE D CG1 1 
ATOM   10152 C CG2 . ILE D 1 244 ? 132.112 100.221 89.037  1.00 101.78 ? 244 ILE D CG2 1 
ATOM   10153 C CD1 . ILE D 1 244 ? 131.552 98.321  91.262  1.00 101.78 ? 244 ILE D CD1 1 
ATOM   10154 N N   . ASN D 1 245 ? 135.027 99.835  87.872  1.00 111.03 ? 245 ASN D N   1 
ATOM   10155 C CA  . ASN D 1 245 ? 135.929 100.408 86.884  1.00 111.03 ? 245 ASN D CA  1 
ATOM   10156 C C   . ASN D 1 245 ? 135.754 101.926 86.821  1.00 111.03 ? 245 ASN D C   1 
ATOM   10157 O O   . ASN D 1 245 ? 134.956 102.523 87.549  1.00 111.03 ? 245 ASN D O   1 
ATOM   10158 C CB  . ASN D 1 245 ? 135.692 99.771  85.516  1.00 111.03 ? 245 ASN D CB  1 
ATOM   10159 C CG  . ASN D 1 245 ? 134.238 99.829  85.083  1.00 111.03 ? 245 ASN D CG  1 
ATOM   10160 O OD1 . ASN D 1 245 ? 133.432 100.561 85.658  1.00 111.03 ? 245 ASN D OD1 1 
ATOM   10161 N ND2 . ASN D 1 245 ? 133.895 99.049  84.065  1.00 111.03 ? 245 ASN D ND2 1 
ATOM   10162 N N   . MET D 1 246 ? 136.516 102.558 85.927  1.00 110.38 ? 246 MET D N   1 
ATOM   10163 C CA  . MET D 1 246 ? 136.501 104.010 85.804  1.00 110.38 ? 246 MET D CA  1 
ATOM   10164 C C   . MET D 1 246 ? 135.383 104.540 84.919  1.00 110.38 ? 246 MET D C   1 
ATOM   10165 O O   . MET D 1 246 ? 135.219 105.762 84.834  1.00 110.38 ? 246 MET D O   1 
ATOM   10166 C CB  . MET D 1 246 ? 137.842 104.513 85.273  1.00 110.38 ? 246 MET D CB  1 
ATOM   10167 C CG  . MET D 1 246 ? 138.976 104.303 86.239  1.00 110.38 ? 246 MET D CG  1 
ATOM   10168 S SD  . MET D 1 246 ? 139.045 105.703 87.364  1.00 110.38 ? 246 MET D SD  1 
ATOM   10169 C CE  . MET D 1 246 ? 140.803 105.891 87.540  1.00 110.38 ? 246 MET D CE  1 
ATOM   10170 N N   . ASP D 1 247 ? 134.623 103.669 84.253  1.00 111.11 ? 247 ASP D N   1 
ATOM   10171 C CA  . ASP D 1 247 ? 133.533 104.149 83.409  1.00 111.11 ? 247 ASP D CA  1 
ATOM   10172 C C   . ASP D 1 247 ? 132.478 104.878 84.233  1.00 111.11 ? 247 ASP D C   1 
ATOM   10173 O O   . ASP D 1 247 ? 131.954 105.914 83.806  1.00 111.11 ? 247 ASP D O   1 
ATOM   10174 C CB  . ASP D 1 247 ? 132.913 102.985 82.638  1.00 111.11 ? 247 ASP D CB  1 
ATOM   10175 C CG  . ASP D 1 247 ? 133.873 102.372 81.637  1.00 111.11 ? 247 ASP D CG  1 
ATOM   10176 O OD1 . ASP D 1 247 ? 135.071 102.728 81.664  1.00 111.11 ? 247 ASP D OD1 1 
ATOM   10177 O OD2 . ASP D 1 247 ? 133.430 101.539 80.820  1.00 111.11 ? 247 ASP D OD2 1 
ATOM   10178 N N   . ALA D 1 248 ? 132.155 104.356 85.414  1.00 102.24 ? 248 ALA D N   1 
ATOM   10179 C CA  . ALA D 1 248 ? 131.207 105.009 86.319  1.00 102.24 ? 248 ALA D CA  1 
ATOM   10180 C C   . ALA D 1 248 ? 131.947 105.905 87.315  1.00 102.24 ? 248 ALA D C   1 
ATOM   10181 O O   . ALA D 1 248 ? 131.818 105.781 88.532  1.00 102.24 ? 248 ALA D O   1 
ATOM   10182 C CB  . ALA D 1 248 ? 130.355 103.966 87.033  1.00 102.24 ? 248 ALA D CB  1 
ATOM   10183 N N   . ALA D 1 249 ? 132.742 106.823 86.763  1.00 97.19  ? 249 ALA D N   1 
ATOM   10184 C CA  . ALA D 1 249 ? 133.525 107.731 87.600  1.00 97.19  ? 249 ALA D CA  1 
ATOM   10185 C C   . ALA D 1 249 ? 132.666 108.607 88.505  1.00 97.19  ? 249 ALA D C   1 
ATOM   10186 O O   . ALA D 1 249 ? 132.994 108.722 89.700  1.00 97.19  ? 249 ALA D O   1 
ATOM   10187 C CB  . ALA D 1 249 ? 134.449 108.576 86.716  1.00 97.19  ? 249 ALA D CB  1 
ATOM   10188 N N   . PRO D 1 250 ? 131.592 109.260 88.031  1.00 95.42  ? 250 PRO D N   1 
ATOM   10189 C CA  . PRO D 1 250 ? 130.777 110.058 88.964  1.00 95.42  ? 250 PRO D CA  1 
ATOM   10190 C C   . PRO D 1 250 ? 130.193 109.239 90.101  1.00 95.42  ? 250 PRO D C   1 
ATOM   10191 O O   . PRO D 1 250 ? 130.097 109.736 91.231  1.00 95.42  ? 250 PRO D O   1 
ATOM   10192 C CB  . PRO D 1 250 ? 129.683 110.647 88.060  1.00 95.42  ? 250 PRO D CB  1 
ATOM   10193 C CG  . PRO D 1 250 ? 129.650 109.758 86.868  1.00 95.42  ? 250 PRO D CG  1 
ATOM   10194 C CD  . PRO D 1 250 ? 131.069 109.350 86.656  1.00 95.42  ? 250 PRO D CD  1 
ATOM   10195 N N   . ALA D 1 251 ? 129.804 107.990 89.835  1.00 89.60  ? 251 ALA D N   1 
ATOM   10196 C CA  . ALA D 1 251 ? 129.326 107.124 90.908  1.00 89.60  ? 251 ALA D CA  1 
ATOM   10197 C C   . ALA D 1 251 ? 130.428 106.854 91.924  1.00 89.60  ? 251 ALA D C   1 
ATOM   10198 O O   . ALA D 1 251 ? 130.179 106.851 93.135  1.00 89.60  ? 251 ALA D O   1 
ATOM   10199 C CB  . ALA D 1 251 ? 128.792 105.814 90.331  1.00 89.60  ? 251 ALA D CB  1 
ATOM   10200 N N   . ARG D 1 252 ? 131.654 106.627 91.447  1.00 92.81  ? 252 ARG D N   1 
ATOM   10201 C CA  . ARG D 1 252 ? 132.779 106.420 92.353  1.00 92.81  ? 252 ARG D CA  1 
ATOM   10202 C C   . ARG D 1 252 ? 132.997 107.642 93.235  1.00 92.81  ? 252 ARG D C   1 
ATOM   10203 O O   . ARG D 1 252 ? 133.176 107.524 94.454  1.00 92.81  ? 252 ARG D O   1 
ATOM   10204 C CB  . ARG D 1 252 ? 134.044 106.110 91.552  1.00 92.81  ? 252 ARG D CB  1 
ATOM   10205 C CG  . ARG D 1 252 ? 134.002 104.802 90.787  1.00 92.81  ? 252 ARG D CG  1 
ATOM   10206 C CD  . ARG D 1 252 ? 134.659 103.684 91.571  1.00 92.81  ? 252 ARG D CD  1 
ATOM   10207 N NE  . ARG D 1 252 ? 136.097 103.876 91.712  1.00 92.81  ? 252 ARG D NE  1 
ATOM   10208 C CZ  . ARG D 1 252 ? 136.996 103.475 90.824  1.00 92.81  ? 252 ARG D CZ  1 
ATOM   10209 N NH1 . ARG D 1 252 ? 136.637 102.877 89.700  1.00 92.81  ? 252 ARG D NH1 1 
ATOM   10210 N NH2 . ARG D 1 252 ? 138.287 103.678 91.069  1.00 92.81  ? 252 ARG D NH2 1 
ATOM   10211 N N   . VAL D 1 253 ? 132.974 108.832 92.629  1.00 87.56  ? 253 VAL D N   1 
ATOM   10212 C CA  . VAL D 1 253 ? 133.187 110.058 93.393  1.00 87.56  ? 253 VAL D CA  1 
ATOM   10213 C C   . VAL D 1 253 ? 132.081 110.245 94.423  1.00 87.56  ? 253 VAL D C   1 
ATOM   10214 O O   . VAL D 1 253 ? 132.346 110.589 95.580  1.00 87.56  ? 253 VAL D O   1 
ATOM   10215 C CB  . VAL D 1 253 ? 133.294 111.271 92.451  1.00 87.56  ? 253 VAL D CB  1 
ATOM   10216 C CG1 . VAL D 1 253 ? 133.647 112.519 93.237  1.00 87.56  ? 253 VAL D CG1 1 
ATOM   10217 C CG2 . VAL D 1 253 ? 134.337 111.017 91.381  1.00 87.56  ? 253 VAL D CG2 1 
ATOM   10218 N N   . ALA D 1 254 ? 130.826 110.020 94.022  1.00 81.65  ? 254 ALA D N   1 
ATOM   10219 C CA  . ALA D 1 254 ? 129.711 110.204 94.946  1.00 81.65  ? 254 ALA D CA  1 
ATOM   10220 C C   . ALA D 1 254 ? 129.782 109.221 96.108  1.00 81.65  ? 254 ALA D C   1 
ATOM   10221 O O   . ALA D 1 254 ? 129.538 109.596 97.262  1.00 81.65  ? 254 ALA D O   1 
ATOM   10222 C CB  . ALA D 1 254 ? 128.384 110.061 94.202  1.00 81.65  ? 254 ALA D CB  1 
ATOM   10223 N N   . LEU D 1 255 ? 130.106 107.956 95.826  1.00 82.64  ? 255 LEU D N   1 
ATOM   10224 C CA  . LEU D 1 255 ? 130.207 106.971 96.897  1.00 82.64  ? 255 LEU D CA  1 
ATOM   10225 C C   . LEU D 1 255 ? 131.352 107.303 97.845  1.00 82.64  ? 255 LEU D C   1 
ATOM   10226 O O   . LEU D 1 255 ? 131.206 107.191 99.068  1.00 82.64  ? 255 LEU D O   1 
ATOM   10227 C CB  . LEU D 1 255 ? 130.370 105.569 96.311  1.00 82.64  ? 255 LEU D CB  1 
ATOM   10228 C CG  . LEU D 1 255 ? 129.108 105.001 95.656  1.00 82.64  ? 255 LEU D CG  1 
ATOM   10229 C CD1 . LEU D 1 255 ? 129.355 103.608 95.097  1.00 82.64  ? 255 LEU D CD1 1 
ATOM   10230 C CD2 . LEU D 1 255 ? 127.948 104.990 96.641  1.00 82.64  ? 255 LEU D CD2 1 
ATOM   10231 N N   . GLY D 1 256 ? 132.496 107.730 97.305  1.00 79.15  ? 256 GLY D N   1 
ATOM   10232 C CA  . GLY D 1 256 ? 133.587 108.148 98.169  1.00 79.15  ? 256 GLY D CA  1 
ATOM   10233 C C   . GLY D 1 256 ? 133.216 109.337 99.035  1.00 79.15  ? 256 GLY D C   1 
ATOM   10234 O O   . GLY D 1 256 ? 133.531 109.374 100.230 1.00 79.15  ? 256 GLY D O   1 
ATOM   10235 N N   . ILE D 1 257 ? 132.524 110.316 98.449  1.00 78.63  ? 257 ILE D N   1 
ATOM   10236 C CA  . ILE D 1 257 ? 132.131 111.502 99.201  1.00 78.63  ? 257 ILE D CA  1 
ATOM   10237 C C   . ILE D 1 257 ? 131.165 111.135 100.318 1.00 78.63  ? 257 ILE D C   1 
ATOM   10238 O O   . ILE D 1 257 ? 131.297 111.616 101.448 1.00 78.63  ? 257 ILE D O   1 
ATOM   10239 C CB  . ILE D 1 257 ? 131.519 112.557 98.264  1.00 78.63  ? 257 ILE D CB  1 
ATOM   10240 C CG1 . ILE D 1 257 ? 132.579 113.148 97.342  1.00 78.63  ? 257 ILE D CG1 1 
ATOM   10241 C CG2 . ILE D 1 257 ? 130.879 113.665 99.070  1.00 78.63  ? 257 ILE D CG2 1 
ATOM   10242 C CD1 . ILE D 1 257 ? 131.983 113.837 96.139  1.00 78.63  ? 257 ILE D CD1 1 
ATOM   10243 N N   . THR D 1 258 ? 130.168 110.296 100.023 1.00 78.62  ? 258 THR D N   1 
ATOM   10244 C CA  . THR D 1 258 ? 129.204 109.945 101.061 1.00 78.62  ? 258 THR D CA  1 
ATOM   10245 C C   . THR D 1 258 ? 129.840 109.078 102.141 1.00 78.62  ? 258 THR D C   1 
ATOM   10246 O O   . THR D 1 258 ? 129.472 109.194 103.316 1.00 78.62  ? 258 THR D O   1 
ATOM   10247 C CB  . THR D 1 258 ? 127.972 109.262 100.456 1.00 78.62  ? 258 THR D CB  1 
ATOM   10248 O OG1 . THR D 1 258 ? 126.952 109.147 101.456 1.00 78.62  ? 258 THR D OG1 1 
ATOM   10249 C CG2 . THR D 1 258 ? 128.301 107.880 99.923  1.00 78.62  ? 258 THR D CG2 1 
ATOM   10250 N N   . THR D 1 259 ? 130.810 108.233 101.778 1.00 79.36  ? 259 THR D N   1 
ATOM   10251 C CA  . THR D 1 259 ? 131.557 107.493 102.789 1.00 79.36  ? 259 THR D CA  1 
ATOM   10252 C C   . THR D 1 259 ? 132.316 108.445 103.706 1.00 79.36  ? 259 THR D C   1 
ATOM   10253 O O   . THR D 1 259 ? 132.275 108.311 104.936 1.00 79.36  ? 259 THR D O   1 
ATOM   10254 C CB  . THR D 1 259 ? 132.518 106.515 102.114 1.00 79.36  ? 259 THR D CB  1 
ATOM   10255 O OG1 . THR D 1 259 ? 131.771 105.549 101.362 1.00 79.36  ? 259 THR D OG1 1 
ATOM   10256 C CG2 . THR D 1 259 ? 133.368 105.802 103.145 1.00 79.36  ? 259 THR D CG2 1 
ATOM   10257 N N   . VAL D 1 260 ? 132.992 109.436 103.118 1.00 80.63  ? 260 VAL D N   1 
ATOM   10258 C CA  . VAL D 1 260 ? 133.723 110.415 103.918 1.00 80.63  ? 260 VAL D CA  1 
ATOM   10259 C C   . VAL D 1 260 ? 132.770 111.180 104.828 1.00 80.63  ? 260 VAL D C   1 
ATOM   10260 O O   . VAL D 1 260 ? 133.062 111.409 106.008 1.00 80.63  ? 260 VAL D O   1 
ATOM   10261 C CB  . VAL D 1 260 ? 134.518 111.364 103.002 1.00 80.63  ? 260 VAL D CB  1 
ATOM   10262 C CG1 . VAL D 1 260 ? 134.910 112.629 103.748 1.00 80.63  ? 260 VAL D CG1 1 
ATOM   10263 C CG2 . VAL D 1 260 ? 135.751 110.662 102.457 1.00 80.63  ? 260 VAL D CG2 1 
ATOM   10264 N N   . LEU D 1 261 ? 131.613 111.581 104.296 1.00 78.88  ? 261 LEU D N   1 
ATOM   10265 C CA  . LEU D 1 261 ? 130.656 112.358 105.077 1.00 78.88  ? 261 LEU D CA  1 
ATOM   10266 C C   . LEU D 1 261 ? 130.118 111.555 106.255 1.00 78.88  ? 261 LEU D C   1 
ATOM   10267 O O   . LEU D 1 261 ? 130.115 112.033 107.397 1.00 78.88  ? 261 LEU D O   1 
ATOM   10268 C CB  . LEU D 1 261 ? 129.510 112.827 104.179 1.00 78.88  ? 261 LEU D CB  1 
ATOM   10269 C CG  . LEU D 1 261 ? 129.528 114.295 103.753 1.00 78.88  ? 261 LEU D CG  1 
ATOM   10270 C CD1 . LEU D 1 261 ? 129.054 115.184 104.891 1.00 78.88  ? 261 LEU D CD1 1 
ATOM   10271 C CD2 . LEU D 1 261 ? 130.917 114.708 103.290 1.00 78.88  ? 261 LEU D CD2 1 
ATOM   10272 N N   . THR D 1 262 ? 129.659 110.327 106.002 1.00 76.88  ? 262 THR D N   1 
ATOM   10273 C CA  . THR D 1 262 ? 129.118 109.531 107.097 1.00 76.88  ? 262 THR D CA  1 
ATOM   10274 C C   . THR D 1 262 ? 130.193 109.195 108.121 1.00 76.88  ? 262 THR D C   1 
ATOM   10275 O O   . THR D 1 262 ? 129.913 109.177 109.326 1.00 76.88  ? 262 THR D O   1 
ATOM   10276 C CB  . THR D 1 262 ? 128.449 108.257 106.570 1.00 76.88  ? 262 THR D CB  1 
ATOM   10277 O OG1 . THR D 1 262 ? 127.822 107.563 107.655 1.00 76.88  ? 262 THR D OG1 1 
ATOM   10278 C CG2 . THR D 1 262 ? 129.453 107.331 105.907 1.00 76.88  ? 262 THR D CG2 1 
ATOM   10279 N N   . MET D 1 263 ? 131.435 108.977 107.683 1.00 76.25  ? 263 MET D N   1 
ATOM   10280 C CA  . MET D 1 263 ? 132.453 108.599 108.651 1.00 76.25  ? 263 MET D CA  1 
ATOM   10281 C C   . MET D 1 263 ? 132.926 109.796 109.469 1.00 76.25  ? 263 MET D C   1 
ATOM   10282 O O   . MET D 1 263 ? 133.210 109.655 110.664 1.00 76.25  ? 263 MET D O   1 
ATOM   10283 C CB  . MET D 1 263 ? 133.622 107.916 107.951 1.00 76.25  ? 263 MET D CB  1 
ATOM   10284 C CG  . MET D 1 263 ? 134.678 107.473 108.921 1.00 76.25  ? 263 MET D CG  1 
ATOM   10285 S SD  . MET D 1 263 ? 134.194 105.859 109.550 1.00 76.25  ? 263 MET D SD  1 
ATOM   10286 C CE  . MET D 1 263 ? 135.764 105.229 110.092 1.00 76.25  ? 263 MET D CE  1 
ATOM   10287 N N   . THR D 1 264 ? 133.007 110.986 108.864 1.00 78.90  ? 264 THR D N   1 
ATOM   10288 C CA  . THR D 1 264 ? 133.334 112.161 109.663 1.00 78.90  ? 264 THR D CA  1 
ATOM   10289 C C   . THR D 1 264 ? 132.197 112.514 110.614 1.00 78.90  ? 264 THR D C   1 
ATOM   10290 O O   . THR D 1 264 ? 132.451 112.989 111.726 1.00 78.90  ? 264 THR D O   1 
ATOM   10291 C CB  . THR D 1 264 ? 133.695 113.356 108.771 1.00 78.90  ? 264 THR D CB  1 
ATOM   10292 O OG1 . THR D 1 264 ? 134.250 114.401 109.578 1.00 78.90  ? 264 THR D OG1 1 
ATOM   10293 C CG2 . THR D 1 264 ? 132.483 113.898 108.037 1.00 78.90  ? 264 THR D CG2 1 
ATOM   10294 N N   . THR D 1 265 ? 130.945 112.260 110.215 1.00 74.99  ? 265 THR D N   1 
ATOM   10295 C CA  . THR D 1 265 ? 129.835 112.419 111.149 1.00 74.99  ? 265 THR D CA  1 
ATOM   10296 C C   . THR D 1 265 ? 129.970 111.459 112.324 1.00 74.99  ? 265 THR D C   1 
ATOM   10297 O O   . THR D 1 265 ? 129.783 111.852 113.483 1.00 74.99  ? 265 THR D O   1 
ATOM   10298 C CB  . THR D 1 265 ? 128.505 112.204 110.423 1.00 74.99  ? 265 THR D CB  1 
ATOM   10299 O OG1 . THR D 1 265 ? 128.129 113.409 109.746 1.00 74.99  ? 265 THR D OG1 1 
ATOM   10300 C CG2 . THR D 1 265 ? 127.407 111.814 111.401 1.00 74.99  ? 265 THR D CG2 1 
ATOM   10301 N N   . GLN D 1 266 ? 130.312 110.199 112.044 1.00 76.61  ? 266 GLN D N   1 
ATOM   10302 C CA  . GLN D 1 266 ? 130.516 109.229 113.116 1.00 76.61  ? 266 GLN D CA  1 
ATOM   10303 C C   . GLN D 1 266 ? 131.640 109.665 114.048 1.00 76.61  ? 266 GLN D C   1 
ATOM   10304 O O   . GLN D 1 266 ? 131.505 109.594 115.276 1.00 76.61  ? 266 GLN D O   1 
ATOM   10305 C CB  . GLN D 1 266 ? 130.821 107.854 112.522 1.00 76.61  ? 266 GLN D CB  1 
ATOM   10306 C CG  . GLN D 1 266 ? 130.478 106.688 113.428 1.00 76.61  ? 266 GLN D CG  1 
ATOM   10307 C CD  . GLN D 1 266 ? 129.120 106.093 113.118 1.00 76.61  ? 266 GLN D CD  1 
ATOM   10308 O OE1 . GLN D 1 266 ? 128.261 106.750 112.532 1.00 76.61  ? 266 GLN D OE1 1 
ATOM   10309 N NE2 . GLN D 1 266 ? 128.920 104.841 113.511 1.00 76.61  ? 266 GLN D NE2 1 
ATOM   10310 N N   . SER D 1 267 ? 132.757 110.124 113.481 1.00 77.78  ? 267 SER D N   1 
ATOM   10311 C CA  . SER D 1 267 ? 133.888 110.547 114.300 1.00 77.78  ? 267 SER D CA  1 
ATOM   10312 C C   . SER D 1 267 ? 133.530 111.748 115.165 1.00 77.78  ? 267 SER D C   1 
ATOM   10313 O O   . SER D 1 267 ? 133.886 111.797 116.349 1.00 77.78  ? 267 SER D O   1 
ATOM   10314 C CB  . SER D 1 267 ? 135.088 110.867 113.409 1.00 77.78  ? 267 SER D CB  1 
ATOM   10315 O OG  . SER D 1 267 ? 134.802 111.956 112.549 1.00 77.78  ? 267 SER D OG  1 
ATOM   10316 N N   . SER D 1 268 ? 132.829 112.731 114.594 1.00 80.18  ? 268 SER D N   1 
ATOM   10317 C CA  . SER D 1 268 ? 132.431 113.900 115.371 1.00 80.18  ? 268 SER D CA  1 
ATOM   10318 C C   . SER D 1 268 ? 131.465 113.519 116.485 1.00 80.18  ? 268 SER D C   1 
ATOM   10319 O O   . SER D 1 268 ? 131.566 114.032 117.605 1.00 80.18  ? 268 SER D O   1 
ATOM   10320 C CB  . SER D 1 268 ? 131.811 114.955 114.455 1.00 80.18  ? 268 SER D CB  1 
ATOM   10321 O OG  . SER D 1 268 ? 132.779 115.498 113.575 1.00 80.18  ? 268 SER D OG  1 
ATOM   10322 N N   . GLY D 1 269 ? 130.524 112.619 116.200 1.00 80.38  ? 269 GLY D N   1 
ATOM   10323 C CA  . GLY D 1 269 ? 129.593 112.180 117.223 1.00 80.38  ? 269 GLY D CA  1 
ATOM   10324 C C   . GLY D 1 269 ? 130.183 111.234 118.245 1.00 80.38  ? 269 GLY D C   1 
ATOM   10325 O O   . GLY D 1 269 ? 129.554 111.001 119.283 1.00 80.38  ? 269 GLY D O   1 
ATOM   10326 N N   . SER D 1 270 ? 131.367 110.682 117.977 1.00 83.35  ? 270 SER D N   1 
ATOM   10327 C CA  . SER D 1 270 ? 131.985 109.761 118.925 1.00 83.35  ? 270 SER D CA  1 
ATOM   10328 C C   . SER D 1 270 ? 132.432 110.476 120.195 1.00 83.35  ? 270 SER D C   1 
ATOM   10329 O O   . SER D 1 270 ? 132.338 109.918 121.293 1.00 83.35  ? 270 SER D O   1 
ATOM   10330 C CB  . SER D 1 270 ? 133.166 109.053 118.266 1.00 83.35  ? 270 SER D CB  1 
ATOM   10331 O OG  . SER D 1 270 ? 132.916 108.824 116.891 1.00 83.35  ? 270 SER D OG  1 
ATOM   10332 N N   . ARG D 1 271 ? 132.917 111.707 120.066 1.00 84.28  ? 271 ARG D N   1 
ATOM   10333 C CA  . ARG D 1 271 ? 133.525 112.430 121.174 1.00 84.28  ? 271 ARG D CA  1 
ATOM   10334 C C   . ARG D 1 271 ? 132.532 113.281 121.955 1.00 84.28  ? 271 ARG D C   1 
ATOM   10335 O O   . ARG D 1 271 ? 132.945 114.012 122.861 1.00 84.28  ? 271 ARG D O   1 
ATOM   10336 C CB  . ARG D 1 271 ? 134.661 113.315 120.652 1.00 84.28  ? 271 ARG D CB  1 
ATOM   10337 C CG  . ARG D 1 271 ? 135.522 112.638 119.597 1.00 84.28  ? 271 ARG D CG  1 
ATOM   10338 C CD  . ARG D 1 271 ? 136.313 113.644 118.778 1.00 84.28  ? 271 ARG D CD  1 
ATOM   10339 N NE  . ARG D 1 271 ? 136.756 113.069 117.513 1.00 84.28  ? 271 ARG D NE  1 
ATOM   10340 C CZ  . ARG D 1 271 ? 137.398 113.740 116.567 1.00 84.28  ? 271 ARG D CZ  1 
ATOM   10341 N NH1 . ARG D 1 271 ? 137.702 115.019 116.711 1.00 84.28  ? 271 ARG D NH1 1 
ATOM   10342 N NH2 . ARG D 1 271 ? 137.744 113.111 115.447 1.00 84.28  ? 271 ARG D NH2 1 
ATOM   10343 N N   . ALA D 1 272 ? 131.240 113.208 121.629 1.00 88.51  ? 272 ALA D N   1 
ATOM   10344 C CA  . ALA D 1 272 ? 130.264 114.080 122.275 1.00 88.51  ? 272 ALA D CA  1 
ATOM   10345 C C   . ALA D 1 272 ? 130.022 113.698 123.730 1.00 88.51  ? 272 ALA D C   1 
ATOM   10346 O O   . ALA D 1 272 ? 129.768 114.575 124.563 1.00 88.51  ? 272 ALA D O   1 
ATOM   10347 C CB  . ALA D 1 272 ? 128.947 114.058 121.499 1.00 88.51  ? 272 ALA D CB  1 
ATOM   10348 N N   . SER D 1 273 ? 130.094 112.411 124.057 1.00 83.89  ? 273 SER D N   1 
ATOM   10349 C CA  . SER D 1 273 ? 129.721 111.918 125.376 1.00 83.89  ? 273 SER D CA  1 
ATOM   10350 C C   . SER D 1 273 ? 130.897 111.819 126.340 1.00 83.89  ? 273 SER D C   1 
ATOM   10351 O O   . SER D 1 273 ? 130.724 111.314 127.454 1.00 83.89  ? 273 SER D O   1 
ATOM   10352 C CB  . SER D 1 273 ? 129.044 110.551 125.251 1.00 83.89  ? 273 SER D CB  1 
ATOM   10353 O OG  . SER D 1 273 ? 129.818 109.672 124.453 1.00 83.89  ? 273 SER D OG  1 
ATOM   10354 N N   . LEU D 1 274 ? 132.080 112.283 125.948 1.00 77.56  ? 274 LEU D N   1 
ATOM   10355 C CA  . LEU D 1 274 ? 133.257 112.100 126.779 1.00 77.56  ? 274 LEU D CA  1 
ATOM   10356 C C   . LEU D 1 274 ? 133.921 113.441 127.071 1.00 77.56  ? 274 LEU D C   1 
ATOM   10357 O O   . LEU D 1 274 ? 133.795 114.382 126.283 1.00 77.56  ? 274 LEU D O   1 
ATOM   10358 C CB  . LEU D 1 274 ? 134.266 111.167 126.098 1.00 77.56  ? 274 LEU D CB  1 
ATOM   10359 C CG  . LEU D 1 274 ? 134.102 109.664 126.346 1.00 77.56  ? 274 LEU D CG  1 
ATOM   10360 C CD1 . LEU D 1 274 ? 134.012 109.370 127.833 1.00 77.56  ? 274 LEU D CD1 1 
ATOM   10361 C CD2 . LEU D 1 274 ? 132.891 109.106 125.610 1.00 77.56  ? 274 LEU D CD2 1 
ATOM   10362 N N   . PRO D 1 275 ? 134.629 113.560 128.196 1.00 78.35  ? 275 PRO D N   1 
ATOM   10363 C CA  . PRO D 1 275 ? 135.262 114.839 128.530 1.00 78.35  ? 275 PRO D CA  1 
ATOM   10364 C C   . PRO D 1 275 ? 136.333 115.214 127.519 1.00 78.35  ? 275 PRO D C   1 
ATOM   10365 O O   . PRO D 1 275 ? 136.988 114.356 126.924 1.00 78.35  ? 275 PRO D O   1 
ATOM   10366 C CB  . PRO D 1 275 ? 135.868 114.584 129.915 1.00 78.35  ? 275 PRO D CB  1 
ATOM   10367 C CG  . PRO D 1 275 ? 136.053 113.110 129.973 1.00 78.35  ? 275 PRO D CG  1 
ATOM   10368 C CD  . PRO D 1 275 ? 134.885 112.542 129.228 1.00 78.35  ? 275 PRO D CD  1 
ATOM   10369 N N   . LYS D 1 276 ? 136.503 116.518 127.329 1.00 74.97  ? 276 LYS D N   1 
ATOM   10370 C CA  . LYS D 1 276 ? 137.504 117.039 126.404 1.00 74.97  ? 276 LYS D CA  1 
ATOM   10371 C C   . LYS D 1 276 ? 138.885 116.799 126.998 1.00 74.97  ? 276 LYS D C   1 
ATOM   10372 O O   . LYS D 1 276 ? 139.322 117.517 127.899 1.00 74.97  ? 276 LYS D O   1 
ATOM   10373 C CB  . LYS D 1 276 ? 137.260 118.521 126.145 1.00 74.97  ? 276 LYS D CB  1 
ATOM   10374 C CG  . LYS D 1 276 ? 135.820 118.851 125.787 1.00 74.97  ? 276 LYS D CG  1 
ATOM   10375 C CD  . LYS D 1 276 ? 135.527 120.330 125.968 1.00 74.97  ? 276 LYS D CD  1 
ATOM   10376 C CE  . LYS D 1 276 ? 134.058 120.631 125.724 1.00 74.97  ? 276 LYS D CE  1 
ATOM   10377 N NZ  . LYS D 1 276 ? 133.174 119.722 126.504 1.00 74.97  ? 276 LYS D NZ  1 
ATOM   10378 N N   . VAL D 1 277 ? 139.580 115.786 126.492 1.00 74.66  ? 277 VAL D N   1 
ATOM   10379 C CA  . VAL D 1 277 ? 140.875 115.373 127.016 1.00 74.66  ? 277 VAL D CA  1 
ATOM   10380 C C   . VAL D 1 277 ? 141.948 115.699 125.989 1.00 74.66  ? 277 VAL D C   1 
ATOM   10381 O O   . VAL D 1 277 ? 141.760 115.481 124.787 1.00 74.66  ? 277 VAL D O   1 
ATOM   10382 C CB  . VAL D 1 277 ? 140.888 113.873 127.369 1.00 74.66  ? 277 VAL D CB  1 
ATOM   10383 C CG1 . VAL D 1 277 ? 140.299 113.655 128.749 1.00 74.66  ? 277 VAL D CG1 1 
ATOM   10384 C CG2 . VAL D 1 277 ? 140.115 113.081 126.330 1.00 74.66  ? 277 VAL D CG2 1 
ATOM   10385 N N   . SER D 1 278 ? 143.072 116.234 126.469 1.00 72.48  ? 278 SER D N   1 
ATOM   10386 C CA  . SER D 1 278 ? 144.157 116.612 125.569 1.00 72.48  ? 278 SER D CA  1 
ATOM   10387 C C   . SER D 1 278 ? 144.744 115.397 124.860 1.00 72.48  ? 278 SER D C   1 
ATOM   10388 O O   . SER D 1 278 ? 145.022 115.447 123.657 1.00 72.48  ? 278 SER D O   1 
ATOM   10389 C CB  . SER D 1 278 ? 145.243 117.356 126.345 1.00 72.48  ? 278 SER D CB  1 
ATOM   10390 O OG  . SER D 1 278 ? 144.689 118.419 127.101 1.00 72.48  ? 278 SER D OG  1 
ATOM   10391 N N   . TYR D 1 279 ? 144.937 114.297 125.585 1.00 70.85  ? 279 TYR D N   1 
ATOM   10392 C CA  . TYR D 1 279 ? 145.556 113.119 124.998 1.00 70.85  ? 279 TYR D CA  1 
ATOM   10393 C C   . TYR D 1 279 ? 144.611 112.443 124.008 1.00 70.85  ? 279 TYR D C   1 
ATOM   10394 O O   . TYR D 1 279 ? 143.417 112.743 123.936 1.00 70.85  ? 279 TYR D O   1 
ATOM   10395 C CB  . TYR D 1 279 ? 145.973 112.130 126.086 1.00 70.85  ? 279 TYR D CB  1 
ATOM   10396 C CG  . TYR D 1 279 ? 144.986 112.000 127.221 1.00 70.85  ? 279 TYR D CG  1 
ATOM   10397 C CD1 . TYR D 1 279 ? 143.860 111.199 127.100 1.00 70.85  ? 279 TYR D CD1 1 
ATOM   10398 C CD2 . TYR D 1 279 ? 145.185 112.671 128.418 1.00 70.85  ? 279 TYR D CD2 1 
ATOM   10399 C CE1 . TYR D 1 279 ? 142.957 111.076 128.137 1.00 70.85  ? 279 TYR D CE1 1 
ATOM   10400 C CE2 . TYR D 1 279 ? 144.288 112.554 129.460 1.00 70.85  ? 279 TYR D CE2 1 
ATOM   10401 C CZ  . TYR D 1 279 ? 143.176 111.756 129.314 1.00 70.85  ? 279 TYR D CZ  1 
ATOM   10402 O OH  . TYR D 1 279 ? 142.281 111.637 130.352 1.00 70.85  ? 279 TYR D OH  1 
ATOM   10403 N N   . VAL D 1 280 ? 145.170 111.518 123.234 1.00 67.58  ? 280 VAL D N   1 
ATOM   10404 C CA  . VAL D 1 280 ? 144.435 110.798 122.200 1.00 67.58  ? 280 VAL D CA  1 
ATOM   10405 C C   . VAL D 1 280 ? 144.093 109.409 122.721 1.00 67.58  ? 280 VAL D C   1 
ATOM   10406 O O   . VAL D 1 280 ? 144.958 108.706 123.259 1.00 67.58  ? 280 VAL D O   1 
ATOM   10407 C CB  . VAL D 1 280 ? 145.245 110.724 120.894 1.00 67.58  ? 280 VAL D CB  1 
ATOM   10408 C CG1 . VAL D 1 280 ? 146.666 110.254 121.167 1.00 67.58  ? 280 VAL D CG1 1 
ATOM   10409 C CG2 . VAL D 1 280 ? 144.557 109.816 119.891 1.00 67.58  ? 280 VAL D CG2 1 
ATOM   10410 N N   . LYS D 1 281 ? 142.832 109.015 122.569 1.00 62.15  ? 281 LYS D N   1 
ATOM   10411 C CA  . LYS D 1 281 ? 142.332 107.752 123.086 1.00 62.15  ? 281 LYS D CA  1 
ATOM   10412 C C   . LYS D 1 281 ? 142.217 106.722 121.964 1.00 62.15  ? 281 LYS D C   1 
ATOM   10413 O O   . LYS D 1 281 ? 142.503 106.996 120.797 1.00 62.15  ? 281 LYS D O   1 
ATOM   10414 C CB  . LYS D 1 281 ? 140.988 107.968 123.780 1.00 62.15  ? 281 LYS D CB  1 
ATOM   10415 C CG  . LYS D 1 281 ? 140.204 109.142 123.230 1.00 62.15  ? 281 LYS D CG  1 
ATOM   10416 C CD  . LYS D 1 281 ? 138.983 109.436 124.075 1.00 62.15  ? 281 LYS D CD  1 
ATOM   10417 C CE  . LYS D 1 281 ? 138.202 110.604 123.510 1.00 62.15  ? 281 LYS D CE  1 
ATOM   10418 N NZ  . LYS D 1 281 ? 136.941 110.829 124.259 1.00 62.15  ? 281 LYS D NZ  1 
ATOM   10419 N N   . ALA D 1 282 ? 141.792 105.511 122.334 1.00 64.78  ? 282 ALA D N   1 
ATOM   10420 C CA  . ALA D 1 282 ? 141.682 104.430 121.359 1.00 64.78  ? 282 ALA D CA  1 
ATOM   10421 C C   . ALA D 1 282 ? 140.631 104.735 120.301 1.00 64.78  ? 282 ALA D C   1 
ATOM   10422 O O   . ALA D 1 282 ? 140.851 104.488 119.109 1.00 64.78  ? 282 ALA D O   1 
ATOM   10423 C CB  . ALA D 1 282 ? 141.355 103.117 122.066 1.00 64.78  ? 282 ALA D CB  1 
ATOM   10424 N N   . ILE D 1 283 ? 139.478 105.262 120.716 1.00 63.72  ? 283 ILE D N   1 
ATOM   10425 C CA  . ILE D 1 283 ? 138.427 105.587 119.757 1.00 63.72  ? 283 ILE D CA  1 
ATOM   10426 C C   . ILE D 1 283 ? 138.913 106.651 118.784 1.00 63.72  ? 283 ILE D C   1 
ATOM   10427 O O   . ILE D 1 283 ? 138.664 106.568 117.574 1.00 63.72  ? 283 ILE D O   1 
ATOM   10428 C CB  . ILE D 1 283 ? 137.148 106.027 120.495 1.00 63.72  ? 283 ILE D CB  1 
ATOM   10429 C CG1 . ILE D 1 283 ? 136.267 104.816 120.798 1.00 63.72  ? 283 ILE D CG1 1 
ATOM   10430 C CG2 . ILE D 1 283 ? 136.371 107.045 119.677 1.00 63.72  ? 283 ILE D CG2 1 
ATOM   10431 C CD1 . ILE D 1 283 ? 135.703 104.153 119.568 1.00 63.72  ? 283 ILE D CD1 1 
ATOM   10432 N N   . ASP D 1 284 ? 139.619 107.663 119.293 1.00 70.80  ? 284 ASP D N   1 
ATOM   10433 C CA  . ASP D 1 284 ? 140.162 108.695 118.419 1.00 70.80  ? 284 ASP D CA  1 
ATOM   10434 C C   . ASP D 1 284 ? 141.127 108.100 117.404 1.00 70.80  ? 284 ASP D C   1 
ATOM   10435 O O   . ASP D 1 284 ? 141.054 108.415 116.211 1.00 70.80  ? 284 ASP D O   1 
ATOM   10436 C CB  . ASP D 1 284 ? 140.859 109.775 119.247 1.00 70.80  ? 284 ASP D CB  1 
ATOM   10437 C CG  . ASP D 1 284 ? 139.885 110.775 119.839 1.00 70.80  ? 284 ASP D CG  1 
ATOM   10438 O OD1 . ASP D 1 284 ? 138.773 110.920 119.290 1.00 70.80  ? 284 ASP D OD1 1 
ATOM   10439 O OD2 . ASP D 1 284 ? 140.233 111.416 120.852 1.00 70.80  ? 284 ASP D OD2 1 
ATOM   10440 N N   . ILE D 1 285 ? 142.023 107.219 117.856 1.00 67.18  ? 285 ILE D N   1 
ATOM   10441 C CA  . ILE D 1 285 ? 142.993 106.608 116.951 1.00 67.18  ? 285 ILE D CA  1 
ATOM   10442 C C   . ILE D 1 285 ? 142.279 105.800 115.876 1.00 67.18  ? 285 ILE D C   1 
ATOM   10443 O O   . ILE D 1 285 ? 142.588 105.910 114.685 1.00 67.18  ? 285 ILE D O   1 
ATOM   10444 C CB  . ILE D 1 285 ? 143.991 105.741 117.738 1.00 67.18  ? 285 ILE D CB  1 
ATOM   10445 C CG1 . ILE D 1 285 ? 145.106 106.607 118.321 1.00 67.18  ? 285 ILE D CG1 1 
ATOM   10446 C CG2 . ILE D 1 285 ? 144.578 104.655 116.853 1.00 67.18  ? 285 ILE D CG2 1 
ATOM   10447 C CD1 . ILE D 1 285 ? 145.910 107.347 117.280 1.00 67.18  ? 285 ILE D CD1 1 
ATOM   10448 N N   . TRP D 1 286 ? 141.300 104.990 116.281 1.00 70.60  ? 286 TRP D N   1 
ATOM   10449 C CA  . TRP D 1 286 ? 140.610 104.125 115.329 1.00 70.60  ? 286 TRP D CA  1 
ATOM   10450 C C   . TRP D 1 286 ? 139.847 104.943 114.292 1.00 70.60  ? 286 TRP D C   1 
ATOM   10451 O O   . TRP D 1 286 ? 139.977 104.711 113.081 1.00 70.60  ? 286 TRP D O   1 
ATOM   10452 C CB  . TRP D 1 286 ? 139.674 103.179 116.081 1.00 70.60  ? 286 TRP D CB  1 
ATOM   10453 C CG  . TRP D 1 286 ? 138.780 102.359 115.209 1.00 70.60  ? 286 TRP D CG  1 
ATOM   10454 C CD1 . TRP D 1 286 ? 137.573 102.726 114.697 1.00 70.60  ? 286 TRP D CD1 1 
ATOM   10455 C CD2 . TRP D 1 286 ? 139.015 101.021 114.760 1.00 70.60  ? 286 TRP D CD2 1 
ATOM   10456 N NE1 . TRP D 1 286 ? 137.043 101.704 113.950 1.00 70.60  ? 286 TRP D NE1 1 
ATOM   10457 C CE2 . TRP D 1 286 ? 137.910 100.645 113.973 1.00 70.60  ? 286 TRP D CE2 1 
ATOM   10458 C CE3 . TRP D 1 286 ? 140.054 100.106 114.944 1.00 70.60  ? 286 TRP D CE3 1 
ATOM   10459 C CZ2 . TRP D 1 286 ? 137.815 99.394  113.370 1.00 70.60  ? 286 TRP D CZ2 1 
ATOM   10460 C CZ3 . TRP D 1 286 ? 139.958 98.865  114.345 1.00 70.60  ? 286 TRP D CZ3 1 
ATOM   10461 C CH2 . TRP D 1 286 ? 138.846 98.520  113.567 1.00 70.60  ? 286 TRP D CH2 1 
ATOM   10462 N N   . MET D 1 287 ? 139.053 105.916 114.749 1.00 72.98  ? 287 MET D N   1 
ATOM   10463 C CA  . MET D 1 287 ? 138.288 106.743 113.821 1.00 72.98  ? 287 MET D CA  1 
ATOM   10464 C C   . MET D 1 287 ? 139.209 107.516 112.887 1.00 72.98  ? 287 MET D C   1 
ATOM   10465 O O   . MET D 1 287 ? 138.979 107.561 111.672 1.00 72.98  ? 287 MET D O   1 
ATOM   10466 C CB  . MET D 1 287 ? 137.378 107.704 114.587 1.00 72.98  ? 287 MET D CB  1 
ATOM   10467 C CG  . MET D 1 287 ? 136.374 107.042 115.514 1.00 72.98  ? 287 MET D CG  1 
ATOM   10468 S SD  . MET D 1 287 ? 135.738 105.478 114.891 1.00 72.98  ? 287 MET D SD  1 
ATOM   10469 C CE  . MET D 1 287 ? 134.272 106.035 114.027 1.00 72.98  ? 287 MET D CE  1 
ATOM   10470 N N   . ALA D 1 288 ? 140.265 108.127 113.434 1.00 74.53  ? 288 ALA D N   1 
ATOM   10471 C CA  . ALA D 1 288 ? 141.169 108.915 112.605 1.00 74.53  ? 288 ALA D CA  1 
ATOM   10472 C C   . ALA D 1 288 ? 141.866 108.046 111.570 1.00 74.53  ? 288 ALA D C   1 
ATOM   10473 O O   . ALA D 1 288 ? 141.970 108.429 110.400 1.00 74.53  ? 288 ALA D O   1 
ATOM   10474 C CB  . ALA D 1 288 ? 142.192 109.633 113.483 1.00 74.53  ? 288 ALA D CB  1 
ATOM   10475 N N   . VAL D 1 289 ? 142.332 106.862 111.973 1.00 72.50  ? 289 VAL D N   1 
ATOM   10476 C CA  . VAL D 1 289 ? 143.056 106.001 111.047 1.00 72.50  ? 289 VAL D CA  1 
ATOM   10477 C C   . VAL D 1 289 ? 142.136 105.505 109.941 1.00 72.50  ? 289 VAL D C   1 
ATOM   10478 O O   . VAL D 1 289 ? 142.515 105.491 108.766 1.00 72.50  ? 289 VAL D O   1 
ATOM   10479 C CB  . VAL D 1 289 ? 143.713 104.833 111.802 1.00 72.50  ? 289 VAL D CB  1 
ATOM   10480 C CG1 . VAL D 1 289 ? 143.853 103.631 110.887 1.00 72.50  ? 289 VAL D CG1 1 
ATOM   10481 C CG2 . VAL D 1 289 ? 145.065 105.253 112.347 1.00 72.50  ? 289 VAL D CG2 1 
ATOM   10482 N N   . CYS D 1 290 ? 140.914 105.092 110.285 1.00 73.67  ? 290 CYS D N   1 
ATOM   10483 C CA  . CYS D 1 290 ? 140.017 104.580 109.252 1.00 73.67  ? 290 CYS D CA  1 
ATOM   10484 C C   . CYS D 1 290 ? 139.546 105.694 108.318 1.00 73.67  ? 290 CYS D C   1 
ATOM   10485 O O   . CYS D 1 290 ? 139.416 105.484 107.102 1.00 73.67  ? 290 CYS D O   1 
ATOM   10486 C CB  . CYS D 1 290 ? 138.838 103.861 109.899 1.00 73.67  ? 290 CYS D CB  1 
ATOM   10487 S SG  . CYS D 1 290 ? 138.233 102.432 108.981 1.00 73.67  ? 290 CYS D SG  1 
ATOM   10488 N N   . LEU D 1 291 ? 139.292 106.891 108.857 1.00 76.20  ? 291 LEU D N   1 
ATOM   10489 C CA  . LEU D 1 291 ? 138.942 108.016 107.998 1.00 76.20  ? 291 LEU D CA  1 
ATOM   10490 C C   . LEU D 1 291 ? 140.102 108.371 107.075 1.00 76.20  ? 291 LEU D C   1 
ATOM   10491 O O   . LEU D 1 291 ? 139.895 108.693 105.899 1.00 76.20  ? 291 LEU D O   1 
ATOM   10492 C CB  . LEU D 1 291 ? 138.511 109.210 108.858 1.00 76.20  ? 291 LEU D CB  1 
ATOM   10493 C CG  . LEU D 1 291 ? 138.355 110.635 108.312 1.00 76.20  ? 291 LEU D CG  1 
ATOM   10494 C CD1 . LEU D 1 291 ? 137.465 111.429 109.251 1.00 76.20  ? 291 LEU D CD1 1 
ATOM   10495 C CD2 . LEU D 1 291 ? 139.683 111.355 108.173 1.00 76.20  ? 291 LEU D CD2 1 
ATOM   10496 N N   . LEU D 1 292 ? 141.333 108.313 107.589 1.00 75.47  ? 292 LEU D N   1 
ATOM   10497 C CA  . LEU D 1 292 ? 142.497 108.516 106.738 1.00 75.47  ? 292 LEU D CA  1 
ATOM   10498 C C   . LEU D 1 292 ? 142.618 107.422 105.688 1.00 75.47  ? 292 LEU D C   1 
ATOM   10499 O O   . LEU D 1 292 ? 143.095 107.683 104.584 1.00 75.47  ? 292 LEU D O   1 
ATOM   10500 C CB  . LEU D 1 292 ? 143.765 108.578 107.586 1.00 75.47  ? 292 LEU D CB  1 
ATOM   10501 C CG  . LEU D 1 292 ? 144.463 109.935 107.654 1.00 75.47  ? 292 LEU D CG  1 
ATOM   10502 C CD1 . LEU D 1 292 ? 143.575 110.953 108.350 1.00 75.47  ? 292 LEU D CD1 1 
ATOM   10503 C CD2 . LEU D 1 292 ? 145.799 109.810 108.364 1.00 75.47  ? 292 LEU D CD2 1 
ATOM   10504 N N   . PHE D 1 293 ? 142.205 106.197 106.017 1.00 75.99  ? 293 PHE D N   1 
ATOM   10505 C CA  . PHE D 1 293 ? 142.185 105.128 105.023 1.00 75.99  ? 293 PHE D CA  1 
ATOM   10506 C C   . PHE D 1 293 ? 141.237 105.465 103.881 1.00 75.99  ? 293 PHE D C   1 
ATOM   10507 O O   . PHE D 1 293 ? 141.582 105.308 102.703 1.00 75.99  ? 293 PHE D O   1 
ATOM   10508 C CB  . PHE D 1 293 ? 141.769 103.811 105.677 1.00 75.99  ? 293 PHE D CB  1 
ATOM   10509 C CG  . PHE D 1 293 ? 142.894 102.843 105.867 1.00 75.99  ? 293 PHE D CG  1 
ATOM   10510 C CD1 . PHE D 1 293 ? 144.091 103.252 106.426 1.00 75.99  ? 293 PHE D CD1 1 
ATOM   10511 C CD2 . PHE D 1 293 ? 142.753 101.520 105.489 1.00 75.99  ? 293 PHE D CD2 1 
ATOM   10512 C CE1 . PHE D 1 293 ? 145.128 102.360 106.604 1.00 75.99  ? 293 PHE D CE1 1 
ATOM   10513 C CE2 . PHE D 1 293 ? 143.786 100.624 105.663 1.00 75.99  ? 293 PHE D CE2 1 
ATOM   10514 C CZ  . PHE D 1 293 ? 144.975 101.044 106.221 1.00 75.99  ? 293 PHE D CZ  1 
ATOM   10515 N N   . VAL D 1 294 ? 140.036 105.935 104.217 1.00 74.25  ? 294 VAL D N   1 
ATOM   10516 C CA  . VAL D 1 294 ? 139.080 106.324 103.182 1.00 74.25  ? 294 VAL D CA  1 
ATOM   10517 C C   . VAL D 1 294 ? 139.630 107.485 102.359 1.00 74.25  ? 294 VAL D C   1 
ATOM   10518 O O   . VAL D 1 294 ? 139.499 107.516 101.126 1.00 74.25  ? 294 VAL D O   1 
ATOM   10519 C CB  . VAL D 1 294 ? 137.719 106.667 103.814 1.00 74.25  ? 294 VAL D CB  1 
ATOM   10520 C CG1 . VAL D 1 294 ? 136.741 107.122 102.746 1.00 74.25  ? 294 VAL D CG1 1 
ATOM   10521 C CG2 . VAL D 1 294 ? 137.172 105.467 104.565 1.00 74.25  ? 294 VAL D CG2 1 
ATOM   10522 N N   . PHE D 1 295 ? 140.257 108.456 103.027 1.00 79.02  ? 295 PHE D N   1 
ATOM   10523 C CA  . PHE D 1 295 ? 140.823 109.598 102.317 1.00 79.02  ? 295 PHE D CA  1 
ATOM   10524 C C   . PHE D 1 295 ? 141.957 109.174 101.392 1.00 79.02  ? 295 PHE D C   1 
ATOM   10525 O O   . PHE D 1 295 ? 142.097 109.707 100.287 1.00 79.02  ? 295 PHE D O   1 
ATOM   10526 C CB  . PHE D 1 295 ? 141.311 110.647 103.314 1.00 79.02  ? 295 PHE D CB  1 
ATOM   10527 C CG  . PHE D 1 295 ? 141.385 112.029 102.743 1.00 79.02  ? 295 PHE D CG  1 
ATOM   10528 C CD1 . PHE D 1 295 ? 140.310 112.564 102.055 1.00 79.02  ? 295 PHE D CD1 1 
ATOM   10529 C CD2 . PHE D 1 295 ? 142.528 112.794 102.890 1.00 79.02  ? 295 PHE D CD2 1 
ATOM   10530 C CE1 . PHE D 1 295 ? 140.372 113.837 101.525 1.00 79.02  ? 295 PHE D CE1 1 
ATOM   10531 C CE2 . PHE D 1 295 ? 142.597 114.068 102.363 1.00 79.02  ? 295 PHE D CE2 1 
ATOM   10532 C CZ  . PHE D 1 295 ? 141.517 114.590 101.680 1.00 79.02  ? 295 PHE D CZ  1 
ATOM   10533 N N   . SER D 1 296 ? 142.786 108.226 101.831 1.00 81.85  ? 296 SER D N   1 
ATOM   10534 C CA  . SER D 1 296 ? 143.858 107.721 100.982 1.00 81.85  ? 296 SER D CA  1 
ATOM   10535 C C   . SER D 1 296 ? 143.296 106.963 99.789  1.00 81.85  ? 296 SER D C   1 
ATOM   10536 O O   . SER D 1 296 ? 143.856 107.025 98.690  1.00 81.85  ? 296 SER D O   1 
ATOM   10537 C CB  . SER D 1 296 ? 144.796 106.826 101.791 1.00 81.85  ? 296 SER D CB  1 
ATOM   10538 O OG  . SER D 1 296 ? 144.189 105.577 102.071 1.00 81.85  ? 296 SER D OG  1 
ATOM   10539 N N   . ALA D 1 297 ? 142.197 106.232 99.988  1.00 80.41  ? 297 ALA D N   1 
ATOM   10540 C CA  . ALA D 1 297 ? 141.536 105.589 98.857  1.00 80.41  ? 297 ALA D CA  1 
ATOM   10541 C C   . ALA D 1 297 ? 141.053 106.624 97.848  1.00 80.41  ? 297 ALA D C   1 
ATOM   10542 O O   . ALA D 1 297 ? 141.217 106.447 96.634  1.00 80.41  ? 297 ALA D O   1 
ATOM   10543 C CB  . ALA D 1 297 ? 140.372 104.729 99.347  1.00 80.41  ? 297 ALA D CB  1 
ATOM   10544 N N   . LEU D 1 298 ? 140.462 107.717 98.335  1.00 80.62  ? 298 LEU D N   1 
ATOM   10545 C CA  . LEU D 1 298 ? 140.027 108.782 97.433  1.00 80.62  ? 298 LEU D CA  1 
ATOM   10546 C C   . LEU D 1 298 ? 141.211 109.420 96.712  1.00 80.62  ? 298 LEU D C   1 
ATOM   10547 O O   . LEU D 1 298 ? 141.129 109.725 95.516  1.00 80.62  ? 298 LEU D O   1 
ATOM   10548 C CB  . LEU D 1 298 ? 139.235 109.836 98.205  1.00 80.62  ? 298 LEU D CB  1 
ATOM   10549 C CG  . LEU D 1 298 ? 137.712 109.753 98.081  1.00 80.62  ? 298 LEU D CG  1 
ATOM   10550 C CD1 . LEU D 1 298 ? 137.284 109.974 96.641  1.00 80.62  ? 298 LEU D CD1 1 
ATOM   10551 C CD2 . LEU D 1 298 ? 137.205 108.416 98.593  1.00 80.62  ? 298 LEU D CD2 1 
ATOM   10552 N N   . LEU D 1 299 ? 142.316 109.638 97.429  1.00 84.97  ? 299 LEU D N   1 
ATOM   10553 C CA  . LEU D 1 299 ? 143.513 110.206 96.813  1.00 84.97  ? 299 LEU D CA  1 
ATOM   10554 C C   . LEU D 1 299 ? 144.061 109.291 95.725  1.00 84.97  ? 299 LEU D C   1 
ATOM   10555 O O   . LEU D 1 299 ? 144.459 109.757 94.651  1.00 84.97  ? 299 LEU D O   1 
ATOM   10556 C CB  . LEU D 1 299 ? 144.578 110.460 97.881  1.00 84.97  ? 299 LEU D CB  1 
ATOM   10557 C CG  . LEU D 1 299 ? 144.624 111.827 98.565  1.00 84.97  ? 299 LEU D CG  1 
ATOM   10558 C CD1 . LEU D 1 299 ? 145.859 111.935 99.440  1.00 84.97  ? 299 LEU D CD1 1 
ATOM   10559 C CD2 . LEU D 1 299 ? 144.619 112.938 97.535  1.00 84.97  ? 299 LEU D CD2 1 
ATOM   10560 N N   . GLU D 1 300 ? 144.099 107.985 95.993  1.00 93.04  ? 300 GLU D N   1 
ATOM   10561 C CA  . GLU D 1 300 ? 144.554 107.032 94.988  1.00 93.04  ? 300 GLU D CA  1 
ATOM   10562 C C   . GLU D 1 300 ? 143.632 107.035 93.777  1.00 93.04  ? 300 GLU D C   1 
ATOM   10563 O O   . GLU D 1 300 ? 144.099 106.983 92.633  1.00 93.04  ? 300 GLU D O   1 
ATOM   10564 C CB  . GLU D 1 300 ? 144.645 105.633 95.598  1.00 93.04  ? 300 GLU D CB  1 
ATOM   10565 C CG  . GLU D 1 300 ? 144.905 104.524 94.593  1.00 93.04  ? 300 GLU D CG  1 
ATOM   10566 C CD  . GLU D 1 300 ? 143.637 103.804 94.180  1.00 93.04  ? 300 GLU D CD  1 
ATOM   10567 O OE1 . GLU D 1 300 ? 142.569 104.102 94.755  1.00 93.04  ? 300 GLU D OE1 1 
ATOM   10568 O OE2 . GLU D 1 300 ? 143.707 102.942 93.279  1.00 93.04  ? 300 GLU D OE2 1 
ATOM   10569 N N   . TYR D 1 301 ? 142.318 107.099 94.006  1.00 89.94  ? 301 TYR D N   1 
ATOM   10570 C CA  . TYR D 1 301 ? 141.384 107.160 92.887  1.00 89.94  ? 301 TYR D CA  1 
ATOM   10571 C C   . TYR D 1 301 ? 141.617 108.408 92.047  1.00 89.94  ? 301 TYR D C   1 
ATOM   10572 O O   . TYR D 1 301 ? 141.600 108.347 90.812  1.00 89.94  ? 301 TYR D O   1 
ATOM   10573 C CB  . TYR D 1 301 ? 139.944 107.122 93.393  1.00 89.94  ? 301 TYR D CB  1 
ATOM   10574 C CG  . TYR D 1 301 ? 138.940 107.602 92.370  1.00 89.94  ? 301 TYR D CG  1 
ATOM   10575 C CD1 . TYR D 1 301 ? 138.578 106.801 91.297  1.00 89.94  ? 301 TYR D CD1 1 
ATOM   10576 C CD2 . TYR D 1 301 ? 138.358 108.857 92.474  1.00 89.94  ? 301 TYR D CD2 1 
ATOM   10577 C CE1 . TYR D 1 301 ? 137.664 107.234 90.359  1.00 89.94  ? 301 TYR D CE1 1 
ATOM   10578 C CE2 . TYR D 1 301 ? 137.443 109.299 91.540  1.00 89.94  ? 301 TYR D CE2 1 
ATOM   10579 C CZ  . TYR D 1 301 ? 137.099 108.483 90.485  1.00 89.94  ? 301 TYR D CZ  1 
ATOM   10580 O OH  . TYR D 1 301 ? 136.188 108.919 89.551  1.00 89.94  ? 301 TYR D OH  1 
ATOM   10581 N N   . ALA D 1 302 ? 141.837 109.551 92.700  1.00 89.60  ? 302 ALA D N   1 
ATOM   10582 C CA  . ALA D 1 302 ? 142.093 110.785 91.964  1.00 89.60  ? 302 ALA D CA  1 
ATOM   10583 C C   . ALA D 1 302 ? 143.390 110.699 91.171  1.00 89.60  ? 302 ALA D C   1 
ATOM   10584 O O   . ALA D 1 302 ? 143.457 111.160 90.026  1.00 89.60  ? 302 ALA D O   1 
ATOM   10585 C CB  . ALA D 1 302 ? 142.132 111.973 92.923  1.00 89.60  ? 302 ALA D CB  1 
ATOM   10586 N N   . ALA D 1 303 ? 144.436 110.119 91.765  1.00 90.70  ? 303 ALA D N   1 
ATOM   10587 C CA  . ALA D 1 303 ? 145.702 109.977 91.051  1.00 90.70  ? 303 ALA D CA  1 
ATOM   10588 C C   . ALA D 1 303 ? 145.553 109.069 89.836  1.00 90.70  ? 303 ALA D C   1 
ATOM   10589 O O   . ALA D 1 303 ? 146.088 109.362 88.759  1.00 90.70  ? 303 ALA D O   1 
ATOM   10590 C CB  . ALA D 1 303 ? 146.781 109.443 91.991  1.00 90.70  ? 303 ALA D CB  1 
ATOM   10591 N N   . VAL D 1 304 ? 144.822 107.963 89.983  1.00 96.44  ? 304 VAL D N   1 
ATOM   10592 C CA  . VAL D 1 304 ? 144.654 107.052 88.856  1.00 96.44  ? 304 VAL D CA  1 
ATOM   10593 C C   . VAL D 1 304 ? 143.785 107.695 87.777  1.00 96.44  ? 304 VAL D C   1 
ATOM   10594 O O   . VAL D 1 304 ? 143.998 107.477 86.579  1.00 96.44  ? 304 VAL D O   1 
ATOM   10595 C CB  . VAL D 1 304 ? 144.088 105.700 89.330  1.00 96.44  ? 304 VAL D CB  1 
ATOM   10596 C CG1 . VAL D 1 304 ? 143.958 104.740 88.163  1.00 96.44  ? 304 VAL D CG1 1 
ATOM   10597 C CG2 . VAL D 1 304 ? 144.984 105.098 90.392  1.00 96.44  ? 304 VAL D CG2 1 
ATOM   10598 N N   . ASN D 1 305 ? 142.795 108.499 88.179  1.00 91.67  ? 305 ASN D N   1 
ATOM   10599 C CA  . ASN D 1 305 ? 142.004 109.238 87.198  1.00 91.67  ? 305 ASN D CA  1 
ATOM   10600 C C   . ASN D 1 305 ? 142.862 110.256 86.456  1.00 91.67  ? 305 ASN D C   1 
ATOM   10601 O O   . ASN D 1 305 ? 142.701 110.452 85.246  1.00 91.67  ? 305 ASN D O   1 
ATOM   10602 C CB  . ASN D 1 305 ? 140.822 109.923 87.884  1.00 91.67  ? 305 ASN D CB  1 
ATOM   10603 C CG  . ASN D 1 305 ? 139.660 110.166 86.940  1.00 91.67  ? 305 ASN D CG  1 
ATOM   10604 O OD1 . ASN D 1 305 ? 139.853 110.514 85.776  1.00 91.67  ? 305 ASN D OD1 1 
ATOM   10605 N ND2 . ASN D 1 305 ? 138.444 109.983 87.439  1.00 91.67  ? 305 ASN D ND2 1 
ATOM   10606 N N   . PHE D 1 306 ? 143.773 110.921 87.170  1.00 93.87  ? 306 PHE D N   1 
ATOM   10607 C CA  . PHE D 1 306 ? 144.732 111.809 86.521  1.00 93.87  ? 306 PHE D CA  1 
ATOM   10608 C C   . PHE D 1 306 ? 145.592 111.043 85.526  1.00 93.87  ? 306 PHE D C   1 
ATOM   10609 O O   . PHE D 1 306 ? 145.931 111.560 84.454  1.00 93.87  ? 306 PHE D O   1 
ATOM   10610 C CB  . PHE D 1 306 ? 145.606 112.492 87.574  1.00 93.87  ? 306 PHE D CB  1 
ATOM   10611 C CG  . PHE D 1 306 ? 146.499 113.569 87.024  1.00 93.87  ? 306 PHE D CG  1 
ATOM   10612 C CD1 . PHE D 1 306 ? 146.040 114.868 86.891  1.00 93.87  ? 306 PHE D CD1 1 
ATOM   10613 C CD2 . PHE D 1 306 ? 147.802 113.284 86.652  1.00 93.87  ? 306 PHE D CD2 1 
ATOM   10614 C CE1 . PHE D 1 306 ? 146.860 115.860 86.390  1.00 93.87  ? 306 PHE D CE1 1 
ATOM   10615 C CE2 . PHE D 1 306 ? 148.626 114.271 86.150  1.00 93.87  ? 306 PHE D CE2 1 
ATOM   10616 C CZ  . PHE D 1 306 ? 148.155 115.561 86.019  1.00 93.87  ? 306 PHE D CZ  1 
ATOM   10617 N N   . VAL D 1 307 ? 145.965 109.812 85.874  1.00 91.86  ? 307 VAL D N   1 
ATOM   10618 C CA  . VAL D 1 307 ? 146.683 108.957 84.933  1.00 91.86  ? 307 VAL D CA  1 
ATOM   10619 C C   . VAL D 1 307 ? 145.833 108.702 83.693  1.00 91.86  ? 307 VAL D C   1 
ATOM   10620 O O   . VAL D 1 307 ? 146.318 108.795 82.559  1.00 91.86  ? 307 VAL D O   1 
ATOM   10621 C CB  . VAL D 1 307 ? 147.099 107.642 85.619  1.00 91.86  ? 307 VAL D CB  1 
ATOM   10622 C CG1 . VAL D 1 307 ? 147.352 106.552 84.587  1.00 91.86  ? 307 VAL D CG1 1 
ATOM   10623 C CG2 . VAL D 1 307 ? 148.331 107.861 86.480  1.00 91.86  ? 307 VAL D CG2 1 
ATOM   10624 N N   . SER D 1 308 ? 144.548 108.395 83.889  1.00 90.87  ? 308 SER D N   1 
ATOM   10625 C CA  . SER D 1 308 ? 143.662 108.102 82.767  1.00 90.87  ? 308 SER D CA  1 
ATOM   10626 C C   . SER D 1 308 ? 143.349 109.333 81.927  1.00 90.87  ? 308 SER D C   1 
ATOM   10627 O O   . SER D 1 308 ? 142.890 109.189 80.789  1.00 90.87  ? 308 SER D O   1 
ATOM   10628 C CB  . SER D 1 308 ? 142.359 107.482 83.272  1.00 90.87  ? 308 SER D CB  1 
ATOM   10629 O OG  . SER D 1 308 ? 141.406 107.377 82.228  1.00 90.87  ? 308 SER D OG  1 
ATOM   10630 N N   . ARG D 1 309 ? 143.581 110.535 82.455  1.00 91.11  ? 309 ARG D N   1 
ATOM   10631 C CA  . ARG D 1 309 ? 143.286 111.773 81.733  1.00 91.11  ? 309 ARG D CA  1 
ATOM   10632 C C   . ARG D 1 309 ? 144.450 112.104 80.798  1.00 91.11  ? 309 ARG D C   1 
ATOM   10633 O O   . ARG D 1 309 ? 145.211 113.053 81.000  1.00 91.11  ? 309 ARG D O   1 
ATOM   10634 C CB  . ARG D 1 309 ? 143.010 112.908 82.710  1.00 91.11  ? 309 ARG D CB  1 
ATOM   10635 N N   . GLN D 1 310 ? 144.572 111.288 79.753  1.00 92.39  ? 310 GLN D N   1 
ATOM   10636 C CA  . GLN D 1 310 ? 145.612 111.439 78.737  1.00 92.39  ? 310 GLN D CA  1 
ATOM   10637 C C   . GLN D 1 310 ? 147.011 111.435 79.350  1.00 92.39  ? 310 GLN D C   1 
ATOM   10638 O O   . GLN D 1 310 ? 147.590 112.489 79.614  1.00 92.39  ? 310 GLN D O   1 
ATOM   10639 C CB  . GLN D 1 310 ? 145.393 112.722 77.929  1.00 92.39  ? 310 GLN D CB  1 
ATOM   10640 C CG  . GLN D 1 310 ? 146.272 112.837 76.694  1.00 92.39  ? 310 GLN D CG  1 
ATOM   10641 C CD  . GLN D 1 310 ? 147.335 113.908 76.835  1.00 92.39  ? 310 GLN D CD  1 
ATOM   10642 O OE1 . GLN D 1 310 ? 147.025 115.090 76.980  1.00 92.39  ? 310 GLN D OE1 1 
ATOM   10643 N NE2 . GLN D 1 310 ? 148.597 113.497 76.796  1.00 92.39  ? 310 GLN D NE2 1 
ATOM   10644 N N   . ARG D 1 376 ? 145.201 100.455 76.342  1.00 90.46  ? 385 ARG D N   1 
ATOM   10645 C CA  . ARG D 1 376 ? 145.030 101.412 75.254  1.00 90.46  ? 385 ARG D CA  1 
ATOM   10646 C C   . ARG D 1 376 ? 145.786 102.705 75.542  1.00 90.46  ? 385 ARG D C   1 
ATOM   10647 O O   . ARG D 1 376 ? 145.631 103.298 76.610  1.00 90.46  ? 385 ARG D O   1 
ATOM   10648 C CB  . ARG D 1 376 ? 143.546 101.706 75.027  1.00 90.46  ? 385 ARG D CB  1 
ATOM   10649 C CG  . ARG D 1 376 ? 143.200 102.104 73.601  1.00 90.46  ? 385 ARG D CG  1 
ATOM   10650 C CD  . ARG D 1 376 ? 143.198 100.899 72.673  1.00 90.46  ? 385 ARG D CD  1 
ATOM   10651 N NE  . ARG D 1 376 ? 142.781 101.253 71.322  1.00 90.46  ? 385 ARG D NE  1 
ATOM   10652 C CZ  . ARG D 1 376 ? 141.519 101.309 70.917  1.00 90.46  ? 385 ARG D CZ  1 
ATOM   10653 N NH1 . ARG D 1 376 ? 140.517 101.039 71.738  1.00 90.46  ? 385 ARG D NH1 1 
ATOM   10654 N NH2 . ARG D 1 376 ? 141.255 101.646 69.658  1.00 90.46  ? 385 ARG D NH2 1 
ATOM   10655 N N   . LYS D 1 377 ? 146.605 103.130 74.577  1.00 91.30  ? 386 LYS D N   1 
ATOM   10656 C CA  . LYS D 1 377 ? 147.402 104.354 74.688  1.00 91.30  ? 386 LYS D CA  1 
ATOM   10657 C C   . LYS D 1 377 ? 148.296 104.325 75.927  1.00 91.30  ? 386 LYS D C   1 
ATOM   10658 O O   . LYS D 1 377 ? 148.501 105.345 76.588  1.00 91.30  ? 386 LYS D O   1 
ATOM   10659 C CB  . LYS D 1 377 ? 146.511 105.598 74.687  1.00 91.30  ? 386 LYS D CB  1 
ATOM   10660 C CG  . LYS D 1 377 ? 147.152 106.821 74.051  1.00 91.30  ? 386 LYS D CG  1 
ATOM   10661 C CD  . LYS D 1 377 ? 146.184 107.991 74.003  1.00 91.30  ? 386 LYS D CD  1 
ATOM   10662 C CE  . LYS D 1 377 ? 144.960 107.661 73.165  1.00 91.30  ? 386 LYS D CE  1 
ATOM   10663 N NZ  . LYS D 1 377 ? 144.043 108.827 73.045  1.00 91.30  ? 386 LYS D NZ  1 
ATOM   10664 N N   . VAL D 1 378 ? 148.814 103.134 76.244  1.00 92.01  ? 387 VAL D N   1 
ATOM   10665 C CA  . VAL D 1 378 ? 149.756 102.858 77.332  1.00 92.01  ? 387 VAL D CA  1 
ATOM   10666 C C   . VAL D 1 378 ? 149.408 103.599 78.622  1.00 92.01  ? 387 VAL D C   1 
ATOM   10667 O O   . VAL D 1 378 ? 150.282 103.861 79.456  1.00 92.01  ? 387 VAL D O   1 
ATOM   10668 C CB  . VAL D 1 378 ? 151.209 103.151 76.894  1.00 92.01  ? 387 VAL D CB  1 
ATOM   10669 C CG1 . VAL D 1 378 ? 151.527 102.418 75.598  1.00 92.01  ? 387 VAL D CG1 1 
ATOM   10670 C CG2 . VAL D 1 378 ? 151.484 104.649 76.746  1.00 92.01  ? 387 VAL D CG2 1 
ATOM   10671 N N   . PHE D 1 379 ? 148.133 103.908 78.813  1.00 94.11  ? 388 PHE D N   1 
ATOM   10672 C CA  . PHE D 1 379 ? 147.668 104.554 80.037  1.00 94.11  ? 388 PHE D CA  1 
ATOM   10673 C C   . PHE D 1 379 ? 146.501 103.823 80.682  1.00 94.11  ? 388 PHE D C   1 
ATOM   10674 O O   . PHE D 1 379 ? 146.426 103.764 81.913  1.00 94.11  ? 388 PHE D O   1 
ATOM   10675 C CB  . PHE D 1 379 ? 147.275 106.013 79.751  1.00 94.11  ? 388 PHE D CB  1 
ATOM   10676 C CG  . PHE D 1 379 ? 148.435 106.968 79.761  1.00 94.11  ? 388 PHE D CG  1 
ATOM   10677 C CD1 . PHE D 1 379 ? 149.541 106.727 80.561  1.00 94.11  ? 388 PHE D CD1 1 
ATOM   10678 C CD2 . PHE D 1 379 ? 148.419 108.108 78.975  1.00 94.11  ? 388 PHE D CD2 1 
ATOM   10679 C CE1 . PHE D 1 379 ? 150.610 107.603 80.574  1.00 94.11  ? 388 PHE D CE1 1 
ATOM   10680 C CE2 . PHE D 1 379 ? 149.486 108.989 78.984  1.00 94.11  ? 388 PHE D CE2 1 
ATOM   10681 C CZ  . PHE D 1 379 ? 150.582 108.736 79.784  1.00 94.11  ? 388 PHE D CZ  1 
ATOM   10682 N N   . ILE D 1 380 ? 145.578 103.323 79.858  1.00 91.81  ? 389 ILE D N   1 
ATOM   10683 C CA  . ILE D 1 380 ? 144.418 102.554 80.395  1.00 91.81  ? 389 ILE D CA  1 
ATOM   10684 C C   . ILE D 1 380 ? 144.969 101.325 81.118  1.00 91.81  ? 389 ILE D C   1 
ATOM   10685 O O   . ILE D 1 380 ? 144.509 101.041 82.240  1.00 91.81  ? 389 ILE D O   1 
ATOM   10686 C CB  . ILE D 1 380 ? 143.454 102.159 79.262  1.00 91.81  ? 389 ILE D CB  1 
ATOM   10687 C CG1 . ILE D 1 380 ? 143.018 103.375 78.440  1.00 91.81  ? 389 ILE D CG1 1 
ATOM   10688 C CG2 . ILE D 1 380 ? 142.263 101.392 79.813  1.00 91.81  ? 389 ILE D CG2 1 
ATOM   10689 C CD1 . ILE D 1 380 ? 142.655 104.581 79.274  1.00 91.81  ? 389 ILE D CD1 1 
ATOM   10690 N N   . ASP D 1 381 ? 145.921 100.629 80.495  1.00 93.92  ? 390 ASP D N   1 
ATOM   10691 C CA  . ASP D 1 381 ? 146.569 99.470  81.158  1.00 93.92  ? 390 ASP D CA  1 
ATOM   10692 C C   . ASP D 1 381 ? 147.103 99.923  82.515  1.00 93.92  ? 390 ASP D C   1 
ATOM   10693 O O   . ASP D 1 381 ? 146.596 99.439  83.543  1.00 93.92  ? 390 ASP D O   1 
ATOM   10694 C CB  . ASP D 1 381 ? 147.704 98.920  80.295  1.00 93.92  ? 390 ASP D CB  1 
ATOM   10695 C CG  . ASP D 1 381 ? 148.374 99.990  79.451  1.00 93.92  ? 390 ASP D CG  1 
ATOM   10696 O OD1 . ASP D 1 381 ? 148.461 101.140 79.925  1.00 93.92  ? 390 ASP D OD1 1 
ATOM   10697 O OD2 . ASP D 1 381 ? 148.800 99.666  78.325  1.00 93.92  ? 390 ASP D OD2 1 
ATOM   10698 N N   . ARG D 1 382 ? 148.089 100.819 82.505  1.00 93.41  ? 391 ARG D N   1 
ATOM   10699 C CA  . ARG D 1 382 ? 148.682 101.321 83.768  1.00 93.41  ? 391 ARG D CA  1 
ATOM   10700 C C   . ARG D 1 382 ? 147.572 101.535 84.792  1.00 93.41  ? 391 ARG D C   1 
ATOM   10701 O O   . ARG D 1 382 ? 147.668 100.965 85.896  1.00 93.41  ? 391 ARG D O   1 
ATOM   10702 C CB  . ARG D 1 382 ? 149.408 102.642 83.512  1.00 93.41  ? 391 ARG D CB  1 
ATOM   10703 C CG  . ARG D 1 382 ? 150.355 102.606 82.322  1.00 93.41  ? 391 ARG D CG  1 
ATOM   10704 C CD  . ARG D 1 382 ? 151.219 103.850 82.261  1.00 93.41  ? 391 ARG D CD  1 
ATOM   10705 N NE  . ARG D 1 382 ? 152.105 103.981 83.407  1.00 93.41  ? 391 ARG D NE  1 
ATOM   10706 C CZ  . ARG D 1 382 ? 152.147 105.044 84.201  1.00 93.41  ? 391 ARG D CZ  1 
ATOM   10707 N NH1 . ARG D 1 382 ? 151.348 106.072 83.972  1.00 93.41  ? 391 ARG D NH1 1 
ATOM   10708 N NH2 . ARG D 1 382 ? 152.987 105.076 85.219  1.00 93.41  ? 391 ARG D NH2 1 
ATOM   10709 N N   . ALA D 1 383 ? 146.550 102.311 84.431  1.00 93.42  ? 392 ALA D N   1 
ATOM   10710 C CA  . ALA D 1 383 ? 145.516 102.632 85.410  1.00 93.42  ? 392 ALA D CA  1 
ATOM   10711 C C   . ALA D 1 383 ? 144.877 101.368 85.971  1.00 93.42  ? 392 ALA D C   1 
ATOM   10712 O O   . ALA D 1 383 ? 144.653 101.261 87.183  1.00 93.42  ? 392 ALA D O   1 
ATOM   10713 C CB  . ALA D 1 383 ? 144.457 103.532 84.774  1.00 93.42  ? 392 ALA D CB  1 
ATOM   10714 N N   . LYS D 1 384 ? 144.583 100.396 85.104  1.00 90.97  ? 393 LYS D N   1 
ATOM   10715 C CA  . LYS D 1 384 ? 143.992 99.145  85.566  1.00 90.97  ? 393 LYS D CA  1 
ATOM   10716 C C   . LYS D 1 384 ? 144.953 98.377  86.465  1.00 90.97  ? 393 LYS D C   1 
ATOM   10717 O O   . LYS D 1 384 ? 144.537 97.780  87.464  1.00 90.97  ? 393 LYS D O   1 
ATOM   10718 C CB  . LYS D 1 384 ? 143.568 98.292  84.370  1.00 90.97  ? 393 LYS D CB  1 
ATOM   10719 C CG  . LYS D 1 384 ? 142.337 98.814  83.646  1.00 90.97  ? 393 LYS D CG  1 
ATOM   10720 C CD  . LYS D 1 384 ? 142.015 97.978  82.417  1.00 90.97  ? 393 LYS D CD  1 
ATOM   10721 C CE  . LYS D 1 384 ? 143.093 98.113  81.356  1.00 90.97  ? 393 LYS D CE  1 
ATOM   10722 N NZ  . LYS D 1 384 ? 142.745 97.381  80.108  1.00 90.97  ? 393 LYS D NZ  1 
ATOM   10723 N N   . LYS D 1 385 ? 146.244 98.377  86.124  1.00 92.11  ? 394 LYS D N   1 
ATOM   10724 C CA  . LYS D 1 385 ? 147.227 97.695  86.960  1.00 92.11  ? 394 LYS D CA  1 
ATOM   10725 C C   . LYS D 1 385 ? 147.329 98.347  88.332  1.00 92.11  ? 394 LYS D C   1 
ATOM   10726 O O   . LYS D 1 385 ? 147.401 97.653  89.353  1.00 92.11  ? 394 LYS D O   1 
ATOM   10727 C CB  . LYS D 1 385 ? 148.590 97.681  86.268  1.00 92.11  ? 394 LYS D CB  1 
ATOM   10728 C CG  . LYS D 1 385 ? 149.542 96.616  86.794  1.00 92.11  ? 394 LYS D CG  1 
ATOM   10729 C CD  . LYS D 1 385 ? 150.523 97.195  87.803  1.00 92.11  ? 394 LYS D CD  1 
ATOM   10730 C CE  . LYS D 1 385 ? 151.531 96.153  88.259  1.00 92.11  ? 394 LYS D CE  1 
ATOM   10731 N NZ  . LYS D 1 385 ? 152.561 96.736  89.163  1.00 92.11  ? 394 LYS D NZ  1 
ATOM   10732 N N   . ILE D 1 386 ? 147.337 99.681  88.378  1.00 92.49  ? 395 ILE D N   1 
ATOM   10733 C CA  . ILE D 1 386 ? 147.403 100.368 89.664  1.00 92.49  ? 395 ILE D CA  1 
ATOM   10734 C C   . ILE D 1 386 ? 146.143 100.097 90.477  1.00 92.49  ? 395 ILE D C   1 
ATOM   10735 O O   . ILE D 1 386 ? 146.205 99.904  91.697  1.00 92.49  ? 395 ILE D O   1 
ATOM   10736 C CB  . ILE D 1 386 ? 147.638 101.876 89.460  1.00 92.49  ? 395 ILE D CB  1 
ATOM   10737 C CG1 . ILE D 1 386 ? 149.022 102.124 88.860  1.00 92.49  ? 395 ILE D CG1 1 
ATOM   10738 C CG2 . ILE D 1 386 ? 147.526 102.613 90.782  1.00 92.49  ? 395 ILE D CG2 1 
ATOM   10739 C CD1 . ILE D 1 386 ? 150.163 101.890 89.827  1.00 92.49  ? 395 ILE D CD1 1 
ATOM   10740 N N   . ASP D 1 387 ? 144.981 100.071 89.817  1.00 92.47  ? 396 ASP D N   1 
ATOM   10741 C CA  . ASP D 1 387 ? 143.738 99.766  90.520  1.00 92.47  ? 396 ASP D CA  1 
ATOM   10742 C C   . ASP D 1 387 ? 143.755 98.353  91.091  1.00 92.47  ? 396 ASP D C   1 
ATOM   10743 O O   . ASP D 1 387 ? 143.323 98.130  92.227  1.00 92.47  ? 396 ASP D O   1 
ATOM   10744 C CB  . ASP D 1 387 ? 142.546 99.953  89.582  1.00 92.47  ? 396 ASP D CB  1 
ATOM   10745 N N   . THR D 1 388 ? 144.250 97.382  90.319  1.00 88.24  ? 397 THR D N   1 
ATOM   10746 C CA  . THR D 1 388 ? 144.339 96.014  90.822  1.00 88.24  ? 397 THR D CA  1 
ATOM   10747 C C   . THR D 1 388 ? 145.327 95.911  91.979  1.00 88.24  ? 397 THR D C   1 
ATOM   10748 O O   . THR D 1 388 ? 145.083 95.181  92.949  1.00 88.24  ? 397 THR D O   1 
ATOM   10749 C CB  . THR D 1 388 ? 144.732 95.060  89.695  1.00 88.24  ? 397 THR D CB  1 
ATOM   10750 O OG1 . THR D 1 388 ? 145.893 95.564  89.023  1.00 88.24  ? 397 THR D OG1 1 
ATOM   10751 C CG2 . THR D 1 388 ? 143.593 94.920  88.697  1.00 88.24  ? 397 THR D CG2 1 
ATOM   10752 N N   . ILE D 1 389 ? 146.448 96.630  91.896  1.00 84.62  ? 398 ILE D N   1 
ATOM   10753 C CA  . ILE D 1 389 ? 147.413 96.631  92.992  1.00 84.62  ? 398 ILE D CA  1 
ATOM   10754 C C   . ILE D 1 389 ? 146.785 97.212  94.251  1.00 84.62  ? 398 ILE D C   1 
ATOM   10755 O O   . ILE D 1 389 ? 146.970 96.687  95.356  1.00 84.62  ? 398 ILE D O   1 
ATOM   10756 C CB  . ILE D 1 389 ? 148.685 97.398  92.586  1.00 84.62  ? 398 ILE D CB  1 
ATOM   10757 N N   . SER D 1 390 ? 146.033 98.305  94.107  1.00 85.97  ? 399 SER D N   1 
ATOM   10758 C CA  . SER D 1 390 ? 145.350 98.888  95.257  1.00 85.97  ? 399 SER D CA  1 
ATOM   10759 C C   . SER D 1 390 ? 144.312 97.928  95.825  1.00 85.97  ? 399 SER D C   1 
ATOM   10760 O O   . SER D 1 390 ? 144.156 97.820  97.046  1.00 85.97  ? 399 SER D O   1 
ATOM   10761 C CB  . SER D 1 390 ? 144.701 100.214 94.865  1.00 85.97  ? 399 SER D CB  1 
ATOM   10762 N N   . ARG D 1 391 ? 143.593 97.219  94.952  1.00 88.10  ? 400 ARG D N   1 
ATOM   10763 C CA  . ARG D 1 391 ? 142.603 96.252  95.416  1.00 88.10  ? 400 ARG D CA  1 
ATOM   10764 C C   . ARG D 1 391 ? 143.253 95.087  96.147  1.00 88.10  ? 400 ARG D C   1 
ATOM   10765 O O   . ARG D 1 391 ? 142.644 94.511  97.055  1.00 88.10  ? 400 ARG D O   1 
ATOM   10766 C CB  . ARG D 1 391 ? 141.778 95.739  94.236  1.00 88.10  ? 400 ARG D CB  1 
ATOM   10767 N N   . ALA D 1 392 ? 144.471 94.712  95.757  1.00 88.24  ? 401 ALA D N   1 
ATOM   10768 C CA  . ALA D 1 392 ? 145.172 93.634  96.441  1.00 88.24  ? 401 ALA D CA  1 
ATOM   10769 C C   . ALA D 1 392 ? 145.919 94.105  97.683  1.00 88.24  ? 401 ALA D C   1 
ATOM   10770 O O   . ALA D 1 392 ? 146.294 93.272  98.515  1.00 88.24  ? 401 ALA D O   1 
ATOM   10771 C CB  . ALA D 1 392 ? 146.151 92.952  95.484  1.00 88.24  ? 401 ALA D CB  1 
ATOM   10772 N N   . CYS D 1 393 ? 146.145 95.410  97.825  1.00 85.82  ? 402 CYS D N   1 
ATOM   10773 C CA  . CYS D 1 393 ? 146.912 95.941  98.947  1.00 85.82  ? 402 CYS D CA  1 
ATOM   10774 C C   . CYS D 1 393 ? 146.050 96.502  100.072 1.00 85.82  ? 402 CYS D C   1 
ATOM   10775 O O   . CYS D 1 393 ? 146.347 96.257  101.245 1.00 85.82  ? 402 CYS D O   1 
ATOM   10776 C CB  . CYS D 1 393 ? 147.869 97.032  98.457  1.00 85.82  ? 402 CYS D CB  1 
ATOM   10777 S SG  . CYS D 1 393 ? 148.732 97.915  99.775  1.00 85.82  ? 402 CYS D SG  1 
ATOM   10778 N N   . PHE D 1 394 ? 144.998 97.256  99.749  1.00 85.41  ? 403 PHE D N   1 
ATOM   10779 C CA  . PHE D 1 394 ? 144.229 97.944  100.785 1.00 85.41  ? 403 PHE D CA  1 
ATOM   10780 C C   . PHE D 1 394 ? 143.578 96.998  101.787 1.00 85.41  ? 403 PHE D C   1 
ATOM   10781 O O   . PHE D 1 394 ? 143.724 97.231  103.000 1.00 85.41  ? 403 PHE D O   1 
ATOM   10782 C CB  . PHE D 1 394 ? 143.192 98.863  100.130 1.00 85.41  ? 403 PHE D CB  1 
ATOM   10783 C CG  . PHE D 1 394 ? 143.696 100.251 99.863  1.00 85.41  ? 403 PHE D CG  1 
ATOM   10784 C CD1 . PHE D 1 394 ? 144.961 100.634 100.276 1.00 85.41  ? 403 PHE D CD1 1 
ATOM   10785 C CD2 . PHE D 1 394 ? 142.904 101.172 99.200  1.00 85.41  ? 403 PHE D CD2 1 
ATOM   10786 C CE1 . PHE D 1 394 ? 145.427 101.910 100.032 1.00 85.41  ? 403 PHE D CE1 1 
ATOM   10787 C CE2 . PHE D 1 394 ? 143.364 102.450 98.953  1.00 85.41  ? 403 PHE D CE2 1 
ATOM   10788 C CZ  . PHE D 1 394 ? 144.628 102.820 99.370  1.00 85.41  ? 403 PHE D CZ  1 
ATOM   10789 N N   . PRO D 1 395 ? 142.841 95.952  101.384 1.00 81.24  ? 404 PRO D N   1 
ATOM   10790 C CA  . PRO D 1 395 ? 142.279 95.048  102.403 1.00 81.24  ? 404 PRO D CA  1 
ATOM   10791 C C   . PRO D 1 395 ? 143.336 94.387  103.268 1.00 81.24  ? 404 PRO D C   1 
ATOM   10792 O O   . PRO D 1 395 ? 143.139 94.246  104.480 1.00 81.24  ? 404 PRO D O   1 
ATOM   10793 C CB  . PRO D 1 395 ? 141.496 94.021  101.570 1.00 81.24  ? 404 PRO D CB  1 
ATOM   10794 C CG  . PRO D 1 395 ? 142.064 94.117  100.204 1.00 81.24  ? 404 PRO D CG  1 
ATOM   10795 C CD  . PRO D 1 395 ? 142.431 95.551  100.027 1.00 81.24  ? 404 PRO D CD  1 
ATOM   10796 N N   . LEU D 1 396 ? 144.468 93.995  102.679 1.00 85.95  ? 405 LEU D N   1 
ATOM   10797 C CA  . LEU D 1 396 ? 145.525 93.366  103.464 1.00 85.95  ? 405 LEU D CA  1 
ATOM   10798 C C   . LEU D 1 396 ? 146.130 94.346  104.461 1.00 85.95  ? 405 LEU D C   1 
ATOM   10799 O O   . LEU D 1 396 ? 146.379 93.988  105.619 1.00 85.95  ? 405 LEU D O   1 
ATOM   10800 C CB  . LEU D 1 396 ? 146.599 92.803  102.535 1.00 85.95  ? 405 LEU D CB  1 
ATOM   10801 C CG  . LEU D 1 396 ? 147.666 91.924  103.188 1.00 85.95  ? 405 LEU D CG  1 
ATOM   10802 C CD1 . LEU D 1 396 ? 147.699 90.552  102.532 1.00 85.95  ? 405 LEU D CD1 1 
ATOM   10803 C CD2 . LEU D 1 396 ? 149.029 92.594  103.110 1.00 85.95  ? 405 LEU D CD2 1 
ATOM   10804 N N   . ALA D 1 397 ? 146.373 95.587  104.030 1.00 85.77  ? 406 ALA D N   1 
ATOM   10805 C CA  . ALA D 1 397 ? 146.906 96.596  104.941 1.00 85.77  ? 406 ALA D CA  1 
ATOM   10806 C C   . ALA D 1 397 ? 145.927 96.890  106.070 1.00 85.77  ? 406 ALA D C   1 
ATOM   10807 O O   . ALA D 1 397 ? 146.326 97.013  107.235 1.00 85.77  ? 406 ALA D O   1 
ATOM   10808 C CB  . ALA D 1 397 ? 147.241 97.873  104.172 1.00 85.77  ? 406 ALA D CB  1 
ATOM   10809 N N   . PHE D 1 398 ? 144.639 97.003  105.745 1.00 82.09  ? 407 PHE D N   1 
ATOM   10810 C CA  . PHE D 1 398 ? 143.644 97.246  106.782 1.00 82.09  ? 407 PHE D CA  1 
ATOM   10811 C C   . PHE D 1 398 ? 143.590 96.091  107.770 1.00 82.09  ? 407 PHE D C   1 
ATOM   10812 O O   . PHE D 1 398 ? 143.509 96.310  108.982 1.00 82.09  ? 407 PHE D O   1 
ATOM   10813 C CB  . PHE D 1 398 ? 142.272 97.479  106.156 1.00 82.09  ? 407 PHE D CB  1 
ATOM   10814 C CG  . PHE D 1 398 ? 141.168 97.643  107.162 1.00 82.09  ? 407 PHE D CG  1 
ATOM   10815 C CD1 . PHE D 1 398 ? 140.984 98.850  107.814 1.00 82.09  ? 407 PHE D CD1 1 
ATOM   10816 C CD2 . PHE D 1 398 ? 140.315 96.593  107.454 1.00 82.09  ? 407 PHE D CD2 1 
ATOM   10817 C CE1 . PHE D 1 398 ? 139.972 99.006  108.739 1.00 82.09  ? 407 PHE D CE1 1 
ATOM   10818 C CE2 . PHE D 1 398 ? 139.301 96.742  108.378 1.00 82.09  ? 407 PHE D CE2 1 
ATOM   10819 C CZ  . PHE D 1 398 ? 139.129 97.951  109.021 1.00 82.09  ? 407 PHE D CZ  1 
ATOM   10820 N N   . LEU D 1 399 ? 143.635 94.853  107.274 1.00 79.92  ? 408 LEU D N   1 
ATOM   10821 C CA  . LEU D 1 399 ? 143.571 93.701  108.166 1.00 79.92  ? 408 LEU D CA  1 
ATOM   10822 C C   . LEU D 1 399 ? 144.803 93.615  109.060 1.00 79.92  ? 408 LEU D C   1 
ATOM   10823 O O   . LEU D 1 399 ? 144.688 93.307  110.253 1.00 79.92  ? 408 LEU D O   1 
ATOM   10824 C CB  . LEU D 1 399 ? 143.401 92.417  107.357 1.00 79.92  ? 408 LEU D CB  1 
ATOM   10825 C CG  . LEU D 1 399 ? 142.005 91.792  107.414 1.00 79.92  ? 408 LEU D CG  1 
ATOM   10826 C CD1 . LEU D 1 399 ? 141.762 91.146  108.767 1.00 79.92  ? 408 LEU D CD1 1 
ATOM   10827 C CD2 . LEU D 1 399 ? 140.932 92.829  107.116 1.00 79.92  ? 408 LEU D CD2 1 
ATOM   10828 N N   . ILE D 1 400 ? 145.991 93.879  108.508 1.00 83.66  ? 409 ILE D N   1 
ATOM   10829 C CA  . ILE D 1 400 ? 147.193 93.804  109.333 1.00 83.66  ? 409 ILE D CA  1 
ATOM   10830 C C   . ILE D 1 400 ? 147.192 94.917  110.377 1.00 83.66  ? 409 ILE D C   1 
ATOM   10831 O O   . ILE D 1 400 ? 147.554 94.690  111.539 1.00 83.66  ? 409 ILE D O   1 
ATOM   10832 C CB  . ILE D 1 400 ? 148.468 93.812  108.465 1.00 83.66  ? 409 ILE D CB  1 
ATOM   10833 C CG1 . ILE D 1 400 ? 149.697 93.499  109.322 1.00 83.66  ? 409 ILE D CG1 1 
ATOM   10834 C CG2 . ILE D 1 400 ? 148.668 95.132  107.753 1.00 83.66  ? 409 ILE D CG2 1 
ATOM   10835 C CD1 . ILE D 1 400 ? 149.629 92.159  110.025 1.00 83.66  ? 409 ILE D CD1 1 
ATOM   10836 N N   . PHE D 1 401 ? 146.749 96.123  110.003 1.00 79.14  ? 410 PHE D N   1 
ATOM   10837 C CA  . PHE D 1 401 ? 146.612 97.177  111.002 1.00 79.14  ? 410 PHE D CA  1 
ATOM   10838 C C   . PHE D 1 401 ? 145.611 96.790  112.078 1.00 79.14  ? 410 PHE D C   1 
ATOM   10839 O O   . PHE D 1 401 ? 145.844 97.028  113.267 1.00 79.14  ? 410 PHE D O   1 
ATOM   10840 C CB  . PHE D 1 401 ? 146.184 98.493  110.357 1.00 79.14  ? 410 PHE D CB  1 
ATOM   10841 C CG  . PHE D 1 401 ? 145.558 99.452  111.332 1.00 79.14  ? 410 PHE D CG  1 
ATOM   10842 C CD1 . PHE D 1 401 ? 146.348 100.215 112.174 1.00 79.14  ? 410 PHE D CD1 1 
ATOM   10843 C CD2 . PHE D 1 401 ? 144.179 99.570  111.424 1.00 79.14  ? 410 PHE D CD2 1 
ATOM   10844 C CE1 . PHE D 1 401 ? 145.777 101.085 113.082 1.00 79.14  ? 410 PHE D CE1 1 
ATOM   10845 C CE2 . PHE D 1 401 ? 143.604 100.436 112.330 1.00 79.14  ? 410 PHE D CE2 1 
ATOM   10846 C CZ  . PHE D 1 401 ? 144.403 101.193 113.161 1.00 79.14  ? 410 PHE D CZ  1 
ATOM   10847 N N   . ASN D 1 402 ? 144.476 96.217  111.674 1.00 77.63  ? 411 ASN D N   1 
ATOM   10848 C CA  . ASN D 1 402 ? 143.441 95.859  112.634 1.00 77.63  ? 411 ASN D CA  1 
ATOM   10849 C C   . ASN D 1 402 ? 143.959 94.839  113.634 1.00 77.63  ? 411 ASN D C   1 
ATOM   10850 O O   . ASN D 1 402 ? 143.780 94.995  114.847 1.00 77.63  ? 411 ASN D O   1 
ATOM   10851 C CB  . ASN D 1 402 ? 142.213 95.322  111.897 1.00 77.63  ? 411 ASN D CB  1 
ATOM   10852 C CG  . ASN D 1 402 ? 141.188 94.715  112.832 1.00 77.63  ? 411 ASN D CG  1 
ATOM   10853 O OD1 . ASN D 1 402 ? 141.288 93.549  113.211 1.00 77.63  ? 411 ASN D OD1 1 
ATOM   10854 N ND2 . ASN D 1 402 ? 140.188 95.505  113.202 1.00 77.63  ? 411 ASN D ND2 1 
ATOM   10855 N N   . ILE D 1 403 ? 144.626 93.794  113.142 1.00 82.26  ? 412 ILE D N   1 
ATOM   10856 C CA  . ILE D 1 403 ? 145.117 92.764  114.050 1.00 82.26  ? 412 ILE D CA  1 
ATOM   10857 C C   . ILE D 1 403 ? 146.214 93.324  114.950 1.00 82.26  ? 412 ILE D C   1 
ATOM   10858 O O   . ILE D 1 403 ? 146.242 93.043  116.155 1.00 82.26  ? 412 ILE D O   1 
ATOM   10859 C CB  . ILE D 1 403 ? 145.573 91.514  113.270 1.00 82.26  ? 412 ILE D CB  1 
ATOM   10860 C CG1 . ILE D 1 403 ? 145.782 90.341  114.231 1.00 82.26  ? 412 ILE D CG1 1 
ATOM   10861 C CG2 . ILE D 1 403 ? 146.830 91.774  112.454 1.00 82.26  ? 412 ILE D CG2 1 
ATOM   10862 C CD1 . ILE D 1 403 ? 144.522 89.923  114.961 1.00 82.26  ? 412 ILE D CD1 1 
ATOM   10863 N N   . PHE D 1 404 ? 147.108 94.154  114.400 1.00 85.29  ? 413 PHE D N   1 
ATOM   10864 C CA  . PHE D 1 404 ? 148.168 94.740  115.214 1.00 85.29  ? 413 PHE D CA  1 
ATOM   10865 C C   . PHE D 1 404 ? 147.586 95.603  116.327 1.00 85.29  ? 413 PHE D C   1 
ATOM   10866 O O   . PHE D 1 404 ? 147.962 95.467  117.498 1.00 85.29  ? 413 PHE D O   1 
ATOM   10867 C CB  . PHE D 1 404 ? 149.107 95.560  114.328 1.00 85.29  ? 413 PHE D CB  1 
ATOM   10868 C CG  . PHE D 1 404 ? 150.447 95.839  114.951 1.00 85.29  ? 413 PHE D CG  1 
ATOM   10869 C CD1 . PHE D 1 404 ? 150.823 95.225  116.135 1.00 85.29  ? 413 PHE D CD1 1 
ATOM   10870 C CD2 . PHE D 1 404 ? 151.330 96.719  114.350 1.00 85.29  ? 413 PHE D CD2 1 
ATOM   10871 C CE1 . PHE D 1 404 ? 152.055 95.484  116.705 1.00 85.29  ? 413 PHE D CE1 1 
ATOM   10872 C CE2 . PHE D 1 404 ? 152.564 96.981  114.916 1.00 85.29  ? 413 PHE D CE2 1 
ATOM   10873 C CZ  . PHE D 1 404 ? 152.926 96.363  116.095 1.00 85.29  ? 413 PHE D CZ  1 
ATOM   10874 N N   . TYR D 1 405 ? 146.650 96.490  115.980 1.00 77.80  ? 414 TYR D N   1 
ATOM   10875 C CA  . TYR D 1 405 ? 146.051 97.372  116.974 1.00 77.80  ? 414 TYR D CA  1 
ATOM   10876 C C   . TYR D 1 405 ? 145.293 96.582  118.031 1.00 77.80  ? 414 TYR D C   1 
ATOM   10877 O O   . TYR D 1 405 ? 145.423 96.853  119.232 1.00 77.80  ? 414 TYR D O   1 
ATOM   10878 C CB  . TYR D 1 405 ? 145.126 98.376  116.286 1.00 77.80  ? 414 TYR D CB  1 
ATOM   10879 C CG  . TYR D 1 405 ? 144.013 98.904  117.163 1.00 77.80  ? 414 TYR D CG  1 
ATOM   10880 C CD1 . TYR D 1 405 ? 144.263 99.862  118.134 1.00 77.80  ? 414 TYR D CD1 1 
ATOM   10881 C CD2 . TYR D 1 405 ? 142.711 98.449  117.014 1.00 77.80  ? 414 TYR D CD2 1 
ATOM   10882 C CE1 . TYR D 1 405 ? 143.251 100.347 118.933 1.00 77.80  ? 414 TYR D CE1 1 
ATOM   10883 C CE2 . TYR D 1 405 ? 141.693 98.930  117.809 1.00 77.80  ? 414 TYR D CE2 1 
ATOM   10884 C CZ  . TYR D 1 405 ? 141.969 99.879  118.766 1.00 77.80  ? 414 TYR D CZ  1 
ATOM   10885 O OH  . TYR D 1 405 ? 140.958 100.362 119.563 1.00 77.80  ? 414 TYR D OH  1 
ATOM   10886 N N   . TRP D 1 406 ? 144.500 95.596  117.607 1.00 75.66  ? 415 TRP D N   1 
ATOM   10887 C CA  . TRP D 1 406 ? 143.708 94.838  118.567 1.00 75.66  ? 415 TRP D CA  1 
ATOM   10888 C C   . TRP D 1 406 ? 144.602 94.073  119.532 1.00 75.66  ? 415 TRP D C   1 
ATOM   10889 O O   . TRP D 1 406 ? 144.382 94.104  120.748 1.00 75.66  ? 415 TRP D O   1 
ATOM   10890 C CB  . TRP D 1 406 ? 142.756 93.895  117.835 1.00 75.66  ? 415 TRP D CB  1 
ATOM   10891 C CG  . TRP D 1 406 ? 141.466 94.550  117.455 1.00 75.66  ? 415 TRP D CG  1 
ATOM   10892 C CD1 . TRP D 1 406 ? 141.141 95.072  116.241 1.00 75.66  ? 415 TRP D CD1 1 
ATOM   10893 C CD2 . TRP D 1 406 ? 140.328 94.761  118.299 1.00 75.66  ? 415 TRP D CD2 1 
ATOM   10894 N NE1 . TRP D 1 406 ? 139.872 95.591  116.272 1.00 75.66  ? 415 TRP D NE1 1 
ATOM   10895 C CE2 . TRP D 1 406 ? 139.350 95.412  117.525 1.00 75.66  ? 415 TRP D CE2 1 
ATOM   10896 C CE3 . TRP D 1 406 ? 140.041 94.458  119.632 1.00 75.66  ? 415 TRP D CE3 1 
ATOM   10897 C CZ2 . TRP D 1 406 ? 138.107 95.767  118.039 1.00 75.66  ? 415 TRP D CZ2 1 
ATOM   10898 C CZ3 . TRP D 1 406 ? 138.805 94.811  120.139 1.00 75.66  ? 415 TRP D CZ3 1 
ATOM   10899 C CH2 . TRP D 1 406 ? 137.854 95.459  119.345 1.00 75.66  ? 415 TRP D CH2 1 
ATOM   10900 N N   . VAL D 1 407 ? 145.641 93.407  119.021 1.00 86.99  ? 416 VAL D N   1 
ATOM   10901 C CA  . VAL D 1 407 ? 146.497 92.638  119.920 1.00 86.99  ? 416 VAL D CA  1 
ATOM   10902 C C   . VAL D 1 407 ? 147.291 93.564  120.836 1.00 86.99  ? 416 VAL D C   1 
ATOM   10903 O O   . VAL D 1 407 ? 147.450 93.278  122.030 1.00 86.99  ? 416 VAL D O   1 
ATOM   10904 C CB  . VAL D 1 407 ? 147.407 91.672  119.135 1.00 86.99  ? 416 VAL D CB  1 
ATOM   10905 C CG1 . VAL D 1 407 ? 146.572 90.766  118.244 1.00 86.99  ? 416 VAL D CG1 1 
ATOM   10906 C CG2 . VAL D 1 407 ? 148.450 92.421  118.317 1.00 86.99  ? 416 VAL D CG2 1 
ATOM   10907 N N   . ILE D 1 408 ? 147.781 94.697  120.315 1.00 90.76  ? 417 ILE D N   1 
ATOM   10908 C CA  . ILE D 1 408 ? 148.581 95.578  121.160 1.00 90.76  ? 417 ILE D CA  1 
ATOM   10909 C C   . ILE D 1 408 ? 147.727 96.165  122.277 1.00 90.76  ? 417 ILE D C   1 
ATOM   10910 O O   . ILE D 1 408 ? 148.134 96.161  123.445 1.00 90.76  ? 417 ILE D O   1 
ATOM   10911 C CB  . ILE D 1 408 ? 149.291 96.664  120.323 1.00 90.76  ? 417 ILE D CB  1 
ATOM   10912 C CG1 . ILE D 1 408 ? 150.366 97.360  121.159 1.00 90.76  ? 417 ILE D CG1 1 
ATOM   10913 C CG2 . ILE D 1 408 ? 148.328 97.700  119.773 1.00 90.76  ? 417 ILE D CG2 1 
ATOM   10914 C CD1 . ILE D 1 408 ? 151.071 98.481  120.432 1.00 90.76  ? 417 ILE D CD1 1 
ATOM   10915 N N   . TYR D 1 409 ? 146.507 96.609  121.960 1.00 85.31  ? 418 TYR D N   1 
ATOM   10916 C CA  . TYR D 1 409 ? 145.654 97.210  122.975 1.00 85.31  ? 418 TYR D CA  1 
ATOM   10917 C C   . TYR D 1 409 ? 144.953 96.179  123.848 1.00 85.31  ? 418 TYR D C   1 
ATOM   10918 O O   . TYR D 1 409 ? 144.389 96.553  124.882 1.00 85.31  ? 418 TYR D O   1 
ATOM   10919 C CB  . TYR D 1 409 ? 144.617 98.122  122.319 1.00 85.31  ? 418 TYR D CB  1 
ATOM   10920 C CG  . TYR D 1 409 ? 145.053 99.565  122.263 1.00 85.31  ? 418 TYR D CG  1 
ATOM   10921 C CD1 . TYR D 1 409 ? 146.391 99.895  122.108 1.00 85.31  ? 418 TYR D CD1 1 
ATOM   10922 C CD2 . TYR D 1 409 ? 144.134 100.597 122.365 1.00 85.31  ? 418 TYR D CD2 1 
ATOM   10923 C CE1 . TYR D 1 409 ? 146.801 101.209 122.056 1.00 85.31  ? 418 TYR D CE1 1 
ATOM   10924 C CE2 . TYR D 1 409 ? 144.536 101.916 122.314 1.00 85.31  ? 418 TYR D CE2 1 
ATOM   10925 C CZ  . TYR D 1 409 ? 145.870 102.216 122.159 1.00 85.31  ? 418 TYR D CZ  1 
ATOM   10926 O OH  . TYR D 1 409 ? 146.276 103.528 122.107 1.00 85.31  ? 418 TYR D OH  1 
ATOM   10927 N N   . LYS D 1 410 ? 144.972 94.902  123.468 1.00 85.25  ? 419 LYS D N   1 
ATOM   10928 C CA  . LYS D 1 410 ? 144.393 93.874  124.319 1.00 85.25  ? 419 LYS D CA  1 
ATOM   10929 C C   . LYS D 1 410 ? 145.408 93.275  125.281 1.00 85.25  ? 419 LYS D C   1 
ATOM   10930 O O   . LYS D 1 410 ? 145.058 92.959  126.422 1.00 85.25  ? 419 LYS D O   1 
ATOM   10931 C CB  . LYS D 1 410 ? 143.776 92.767  123.462 1.00 85.25  ? 419 LYS D CB  1 
ATOM   10932 C CG  . LYS D 1 410 ? 142.290 92.940  123.217 1.00 85.25  ? 419 LYS D CG  1 
ATOM   10933 C CD  . LYS D 1 410 ? 141.526 93.027  124.526 1.00 85.25  ? 419 LYS D CD  1 
ATOM   10934 C CE  . LYS D 1 410 ? 140.038 93.191  124.280 1.00 85.25  ? 419 LYS D CE  1 
ATOM   10935 N NZ  . LYS D 1 410 ? 139.492 92.073  123.465 1.00 85.25  ? 419 LYS D NZ  1 
ATOM   10936 N N   . ILE D 1 411 ? 146.664 93.111  124.856 1.00 92.41  ? 420 ILE D N   1 
ATOM   10937 C CA  . ILE D 1 411 ? 147.689 92.469  125.668 1.00 92.41  ? 420 ILE D CA  1 
ATOM   10938 C C   . ILE D 1 411 ? 148.846 93.415  125.967 1.00 92.41  ? 420 ILE D C   1 
ATOM   10939 O O   . ILE D 1 411 ? 149.215 93.614  127.129 1.00 92.41  ? 420 ILE D O   1 
ATOM   10940 C CB  . ILE D 1 411 ? 148.206 91.173  125.004 1.00 92.41  ? 420 ILE D CB  1 
ATOM   10941 C CG1 . ILE D 1 411 ? 147.043 90.228  124.694 1.00 92.41  ? 420 ILE D CG1 1 
ATOM   10942 C CG2 . ILE D 1 411 ? 149.223 90.486  125.899 1.00 92.41  ? 420 ILE D CG2 1 
ATOM   10943 C CD1 . ILE D 1 411 ? 147.466 88.950  124.007 1.00 92.41  ? 420 ILE D CD1 1 
ATOM   10944 N N   . LEU D 1 412 ? 149.435 94.009  124.927 1.00 96.92  ? 421 LEU D N   1 
ATOM   10945 C CA  . LEU D 1 412 ? 150.703 94.708  125.111 1.00 96.92  ? 421 LEU D CA  1 
ATOM   10946 C C   . LEU D 1 412 ? 150.523 96.006  125.887 1.00 96.92  ? 421 LEU D C   1 
ATOM   10947 O O   . LEU D 1 412 ? 151.313 96.309  126.790 1.00 96.92  ? 421 LEU D O   1 
ATOM   10948 C CB  . LEU D 1 412 ? 151.354 94.977  123.755 1.00 96.92  ? 421 LEU D CB  1 
ATOM   10949 C CG  . LEU D 1 412 ? 152.805 95.464  123.785 1.00 96.92  ? 421 LEU D CG  1 
ATOM   10950 C CD1 . LEU D 1 412 ? 153.646 94.594  124.705 1.00 96.92  ? 421 LEU D CD1 1 
ATOM   10951 C CD2 . LEU D 1 412 ? 153.392 95.486  122.382 1.00 96.92  ? 421 LEU D CD2 1 
ATOM   10952 N N   . ARG D 1 413 ? 149.495 96.788  125.556 1.00 98.39  ? 422 ARG D N   1 
ATOM   10953 C CA  . ARG D 1 413 ? 149.331 98.093  126.187 1.00 98.39  ? 422 ARG D CA  1 
ATOM   10954 C C   . ARG D 1 413 ? 148.619 97.979  127.532 1.00 98.39  ? 422 ARG D C   1 
ATOM   10955 O O   . ARG D 1 413 ? 149.181 98.331  128.574 1.00 98.39  ? 422 ARG D O   1 
ATOM   10956 C CB  . ARG D 1 413 ? 148.574 99.037  125.250 1.00 98.39  ? 422 ARG D CB  1 
ATOM   10957 C CG  . ARG D 1 413 ? 149.377 99.456  124.030 1.00 98.39  ? 422 ARG D CG  1 
ATOM   10958 C CD  . ARG D 1 413 ? 150.668 100.159 124.427 1.00 98.39  ? 422 ARG D CD  1 
ATOM   10959 N NE  . ARG D 1 413 ? 151.105 101.117 123.418 1.00 98.39  ? 422 ARG D NE  1 
ATOM   10960 C CZ  . ARG D 1 413 ? 152.338 101.599 123.326 1.00 98.39  ? 422 ARG D CZ  1 
ATOM   10961 N NH1 . ARG D 1 413 ? 153.290 101.227 124.165 1.00 98.39  ? 422 ARG D NH1 1 
ATOM   10962 N NH2 . ARG D 1 413 ? 152.622 102.473 122.365 1.00 98.39  ? 422 ARG D NH2 1 
ATOM   10963 N N   . HIS D 1 414 ? 147.381 97.489  127.528 1.00 98.86  ? 423 HIS D N   1 
ATOM   10964 C CA  . HIS D 1 414 ? 146.591 97.423  128.749 1.00 98.86  ? 423 HIS D CA  1 
ATOM   10965 C C   . HIS D 1 414 ? 145.717 96.178  128.728 1.00 98.86  ? 423 HIS D C   1 
ATOM   10966 O O   . HIS D 1 414 ? 145.527 95.544  127.686 1.00 98.86  ? 423 HIS D O   1 
ATOM   10967 C CB  . HIS D 1 414 ? 145.713 98.669  128.931 1.00 98.86  ? 423 HIS D CB  1 
ATOM   10968 C CG  . HIS D 1 414 ? 146.419 99.959  128.647 1.00 98.86  ? 423 HIS D CG  1 
ATOM   10969 N ND1 . HIS D 1 414 ? 146.434 100.539 127.397 1.00 98.86  ? 423 HIS D ND1 1 
ATOM   10970 C CD2 . HIS D 1 414 ? 147.133 100.781 129.452 1.00 98.86  ? 423 HIS D CD2 1 
ATOM   10971 C CE1 . HIS D 1 414 ? 147.128 101.662 127.443 1.00 98.86  ? 423 HIS D CE1 1 
ATOM   10972 N NE2 . HIS D 1 414 ? 147.563 101.832 128.678 1.00 98.86  ? 423 HIS D NE2 1 
ATOM   10973 N N   . GLU D 1 415 ? 145.201 95.833  129.910 1.00 91.03  ? 424 GLU D N   1 
ATOM   10974 C CA  . GLU D 1 415 ? 144.237 94.753  130.102 1.00 91.03  ? 424 GLU D CA  1 
ATOM   10975 C C   . GLU D 1 415 ? 144.835 93.384  129.791 1.00 91.03  ? 424 GLU D C   1 
ATOM   10976 O O   . GLU D 1 415 ? 145.953 93.288  129.273 1.00 91.03  ? 424 GLU D O   1 
ATOM   10977 C CB  . GLU D 1 415 ? 142.985 94.997  129.253 1.00 91.03  ? 424 GLU D CB  1 
ATOM   10978 C CG  . GLU D 1 415 ? 141.679 94.670  129.962 1.00 91.03  ? 424 GLU D CG  1 
ATOM   10979 C CD  . GLU D 1 415 ? 140.490 95.391  129.357 1.00 91.03  ? 424 GLU D CD  1 
ATOM   10980 O OE1 . GLU D 1 415 ? 140.689 96.463  128.751 1.00 91.03  ? 424 GLU D OE1 1 
ATOM   10981 O OE2 . GLU D 1 415 ? 139.355 94.885  129.488 1.00 91.03  ? 424 GLU D OE2 1 
ATOM   10982 N N   . ASP D 1 416 ? 144.095 92.326  130.119 1.00 91.68  ? 425 ASP D N   1 
ATOM   10983 C CA  . ASP D 1 416 ? 144.540 90.943  129.938 1.00 91.68  ? 425 ASP D CA  1 
ATOM   10984 C C   . ASP D 1 416 ? 145.893 90.689  130.597 1.00 91.68  ? 425 ASP D C   1 
ATOM   10985 O O   . ASP D 1 416 ? 146.168 91.195  131.685 1.00 91.68  ? 425 ASP D O   1 
ATOM   10986 C CB  . ASP D 1 416 ? 144.609 90.585  128.451 1.00 91.68  ? 425 ASP D CB  1 
ATOM   10987 C CG  . ASP D 1 416 ? 143.338 89.927  127.951 1.00 91.68  ? 425 ASP D CG  1 
ATOM   10988 O OD1 . ASP D 1 416 ? 142.676 89.229  128.746 1.00 91.68  ? 425 ASP D OD1 1 
ATOM   10989 O OD2 . ASP D 1 416 ? 143.004 90.106  126.761 1.00 91.68  ? 425 ASP D OD2 1 
ATOM   10990 N N   . VAL E 2 27  ? 142.110 119.531 187.531 1.00 79.28  ? 29  VAL E N   1 
ATOM   10991 C CA  . VAL E 2 27  ? 140.838 119.965 186.968 1.00 79.28  ? 29  VAL E CA  1 
ATOM   10992 C C   . VAL E 2 27  ? 140.581 119.266 185.638 1.00 79.28  ? 29  VAL E C   1 
ATOM   10993 O O   . VAL E 2 27  ? 141.505 119.061 184.849 1.00 79.28  ? 29  VAL E O   1 
ATOM   10994 C CB  . VAL E 2 27  ? 140.797 121.497 186.799 1.00 79.28  ? 29  VAL E CB  1 
ATOM   10995 C CG1 . VAL E 2 27  ? 140.752 122.178 188.157 1.00 79.28  ? 29  VAL E CG1 1 
ATOM   10996 C CG2 . VAL E 2 27  ? 141.998 121.980 186.000 1.00 79.28  ? 29  VAL E CG2 1 
ATOM   10997 N N   . PRO E 2 28  ? 139.330 118.888 185.390 1.00 78.61  ? 30  PRO E N   1 
ATOM   10998 C CA  . PRO E 2 28  ? 138.988 118.254 184.113 1.00 78.61  ? 30  PRO E CA  1 
ATOM   10999 C C   . PRO E 2 28  ? 138.999 119.269 182.981 1.00 78.61  ? 30  PRO E C   1 
ATOM   11000 O O   . PRO E 2 28  ? 138.992 120.483 183.190 1.00 78.61  ? 30  PRO E O   1 
ATOM   11001 C CB  . PRO E 2 28  ? 137.584 117.700 184.357 1.00 78.61  ? 30  PRO E CB  1 
ATOM   11002 C CG  . PRO E 2 28  ? 137.010 118.603 185.394 1.00 78.61  ? 30  PRO E CG  1 
ATOM   11003 C CD  . PRO E 2 28  ? 138.159 119.021 186.275 1.00 78.61  ? 30  PRO E CD  1 
ATOM   11004 N N   . ALA E 2 29  ? 139.022 118.743 181.754 1.00 72.61  ? 31  ALA E N   1 
ATOM   11005 C CA  . ALA E 2 29  ? 138.989 119.614 180.584 1.00 72.61  ? 31  ALA E CA  1 
ATOM   11006 C C   . ALA E 2 29  ? 137.714 120.443 180.543 1.00 72.61  ? 31  ALA E C   1 
ATOM   11007 O O   . ALA E 2 29  ? 137.706 121.545 179.983 1.00 72.61  ? 31  ALA E O   1 
ATOM   11008 C CB  . ALA E 2 29  ? 139.129 118.788 179.307 1.00 72.61  ? 31  ALA E CB  1 
ATOM   11009 N N   . ASN E 2 30  ? 136.631 119.933 181.133 1.00 69.92  ? 32  ASN E N   1 
ATOM   11010 C CA  . ASN E 2 30  ? 135.389 120.694 181.182 1.00 69.92  ? 32  ASN E CA  1 
ATOM   11011 C C   . ASN E 2 30  ? 135.559 121.976 181.986 1.00 69.92  ? 32  ASN E C   1 
ATOM   11012 O O   . ASN E 2 30  ? 135.048 123.031 181.597 1.00 69.92  ? 32  ASN E O   1 
ATOM   11013 C CB  . ASN E 2 30  ? 134.271 119.836 181.770 1.00 69.92  ? 32  ASN E CB  1 
ATOM   11014 C CG  . ASN E 2 30  ? 133.255 119.414 180.731 1.00 69.92  ? 32  ASN E CG  1 
ATOM   11015 O OD1 . ASN E 2 30  ? 133.453 119.619 179.535 1.00 69.92  ? 32  ASN E OD1 1 
ATOM   11016 N ND2 . ASN E 2 30  ? 132.157 118.821 181.184 1.00 69.92  ? 32  ASN E ND2 1 
ATOM   11017 N N   . SER E 2 31  ? 136.278 121.905 183.108 1.00 72.47  ? 33  SER E N   1 
ATOM   11018 C CA  . SER E 2 31  ? 136.446 123.082 183.955 1.00 72.47  ? 33  SER E CA  1 
ATOM   11019 C C   . SER E 2 31  ? 137.191 124.190 183.220 1.00 72.47  ? 33  SER E C   1 
ATOM   11020 O O   . SER E 2 31  ? 136.731 125.337 183.173 1.00 72.47  ? 33  SER E O   1 
ATOM   11021 C CB  . SER E 2 31  ? 137.177 122.702 185.242 1.00 72.47  ? 33  SER E CB  1 
ATOM   11022 O OG  . SER E 2 31  ? 137.261 123.807 186.125 1.00 72.47  ? 33  SER E OG  1 
ATOM   11023 N N   . THR E 2 32  ? 138.346 123.865 182.632 1.00 72.86  ? 34  THR E N   1 
ATOM   11024 C CA  . THR E 2 32  ? 139.104 124.878 181.904 1.00 72.86  ? 34  THR E CA  1 
ATOM   11025 C C   . THR E 2 32  ? 138.340 125.368 180.681 1.00 72.86  ? 34  THR E C   1 
ATOM   11026 O O   . THR E 2 32  ? 138.355 126.567 180.377 1.00 72.86  ? 34  THR E O   1 
ATOM   11027 C CB  . THR E 2 32  ? 140.479 124.339 181.499 1.00 72.86  ? 34  THR E CB  1 
ATOM   11028 O OG1 . THR E 2 32  ? 141.042 125.177 180.481 1.00 72.86  ? 34  THR E OG1 1 
ATOM   11029 C CG2 . THR E 2 32  ? 140.377 122.921 180.977 1.00 72.86  ? 34  THR E CG2 1 
ATOM   11030 N N   . SER E 2 33  ? 137.659 124.461 179.974 1.00 71.54  ? 35  SER E N   1 
ATOM   11031 C CA  . SER E 2 33  ? 136.893 124.871 178.802 1.00 71.54  ? 35  SER E CA  1 
ATOM   11032 C C   . SER E 2 33  ? 135.801 125.861 179.180 1.00 71.54  ? 35  SER E C   1 
ATOM   11033 O O   . SER E 2 33  ? 135.613 126.874 178.498 1.00 71.54  ? 35  SER E O   1 
ATOM   11034 C CB  . SER E 2 33  ? 136.291 123.648 178.112 1.00 71.54  ? 35  SER E CB  1 
ATOM   11035 O OG  . SER E 2 33  ? 135.222 123.115 178.872 1.00 71.54  ? 35  SER E OG  1 
ATOM   11036 N N   . ASN E 2 34  ? 135.081 125.596 180.273 1.00 71.52  ? 36  ASN E N   1 
ATOM   11037 C CA  . ASN E 2 34  ? 134.055 126.527 180.729 1.00 71.52  ? 36  ASN E CA  1 
ATOM   11038 C C   . ASN E 2 34  ? 134.667 127.840 181.196 1.00 71.52  ? 36  ASN E C   1 
ATOM   11039 O O   . ASN E 2 34  ? 134.103 128.914 180.955 1.00 71.52  ? 36  ASN E O   1 
ATOM   11040 C CB  . ASN E 2 34  ? 133.232 125.896 181.851 1.00 71.52  ? 36  ASN E CB  1 
ATOM   11041 C CG  . ASN E 2 34  ? 132.495 124.653 181.404 1.00 71.52  ? 36  ASN E CG  1 
ATOM   11042 O OD1 . ASN E 2 34  ? 132.330 124.412 180.209 1.00 71.52  ? 36  ASN E OD1 1 
ATOM   11043 N ND2 . ASN E 2 34  ? 132.048 123.854 182.365 1.00 71.52  ? 36  ASN E ND2 1 
ATOM   11044 N N   . ILE E 2 35  ? 135.816 127.777 181.873 1.00 72.28  ? 37  ILE E N   1 
ATOM   11045 C CA  . ILE E 2 35  ? 136.444 128.994 182.377 1.00 72.28  ? 37  ILE E CA  1 
ATOM   11046 C C   . ILE E 2 35  ? 136.848 129.906 181.225 1.00 72.28  ? 37  ILE E C   1 
ATOM   11047 O O   . ILE E 2 35  ? 136.616 131.120 181.266 1.00 72.28  ? 37  ILE E O   1 
ATOM   11048 C CB  . ILE E 2 35  ? 137.643 128.643 183.277 1.00 72.28  ? 37  ILE E CB  1 
ATOM   11049 C CG1 . ILE E 2 35  ? 137.154 128.181 184.650 1.00 72.28  ? 37  ILE E CG1 1 
ATOM   11050 C CG2 . ILE E 2 35  ? 138.570 129.837 183.429 1.00 72.28  ? 37  ILE E CG2 1 
ATOM   11051 C CD1 . ILE E 2 35  ? 136.306 129.204 185.369 1.00 72.28  ? 37  ILE E CD1 1 
ATOM   11052 N N   . LEU E 2 36  ? 137.452 129.340 180.176 1.00 69.96  ? 38  LEU E N   1 
ATOM   11053 C CA  . LEU E 2 36  ? 137.881 130.178 179.060 1.00 69.96  ? 38  LEU E CA  1 
ATOM   11054 C C   . LEU E 2 36  ? 136.690 130.689 178.254 1.00 69.96  ? 38  LEU E C   1 
ATOM   11055 O O   . LEU E 2 36  ? 136.699 131.835 177.793 1.00 69.96  ? 38  LEU E O   1 
ATOM   11056 C CB  . LEU E 2 36  ? 138.876 129.426 178.174 1.00 69.96  ? 38  LEU E CB  1 
ATOM   11057 C CG  . LEU E 2 36  ? 138.531 128.081 177.536 1.00 69.96  ? 38  LEU E CG  1 
ATOM   11058 C CD1 . LEU E 2 36  ? 138.093 128.273 176.104 1.00 69.96  ? 38  LEU E CD1 1 
ATOM   11059 C CD2 . LEU E 2 36  ? 139.736 127.156 177.593 1.00 69.96  ? 38  LEU E CD2 1 
ATOM   11060 N N   . ASN E 2 37  ? 135.655 129.867 178.075 1.00 76.37  ? 39  ASN E N   1 
ATOM   11061 C CA  . ASN E 2 37  ? 134.419 130.353 177.473 1.00 76.37  ? 39  ASN E CA  1 
ATOM   11062 C C   . ASN E 2 37  ? 133.268 129.451 177.896 1.00 76.37  ? 39  ASN E C   1 
ATOM   11063 O O   . ASN E 2 37  ? 133.414 128.229 177.944 1.00 76.37  ? 39  ASN E O   1 
ATOM   11064 C CB  . ASN E 2 37  ? 134.508 130.421 175.940 1.00 76.37  ? 39  ASN E CB  1 
ATOM   11065 C CG  . ASN E 2 37  ? 134.157 129.106 175.264 1.00 76.37  ? 39  ASN E CG  1 
ATOM   11066 O OD1 . ASN E 2 37  ? 135.039 128.323 174.909 1.00 76.37  ? 39  ASN E OD1 1 
ATOM   11067 N ND2 . ASN E 2 37  ? 132.869 128.848 175.098 1.00 76.37  ? 39  ASN E ND2 1 
ATOM   11068 N N   . ARG E 2 38  ? 132.126 130.066 178.189 1.00 87.24  ? 40  ARG E N   1 
ATOM   11069 C CA  . ARG E 2 38  ? 130.915 129.359 178.584 1.00 87.24  ? 40  ARG E CA  1 
ATOM   11070 C C   . ARG E 2 38  ? 129.797 130.382 178.698 1.00 87.24  ? 40  ARG E C   1 
ATOM   11071 O O   . ARG E 2 38  ? 130.045 131.570 178.923 1.00 87.24  ? 40  ARG E O   1 
ATOM   11072 C CB  . ARG E 2 38  ? 131.095 128.608 179.911 1.00 87.24  ? 40  ARG E CB  1 
ATOM   11073 C CG  . ARG E 2 38  ? 129.927 127.708 180.308 1.00 87.24  ? 40  ARG E CG  1 
ATOM   11074 C CD  . ARG E 2 38  ? 129.875 126.443 179.464 1.00 87.24  ? 40  ARG E CD  1 
ATOM   11075 N NE  . ARG E 2 38  ? 128.980 125.443 180.036 1.00 87.24  ? 40  ARG E NE  1 
ATOM   11076 C CZ  . ARG E 2 38  ? 128.981 124.157 179.707 1.00 87.24  ? 40  ARG E CZ  1 
ATOM   11077 N NH1 . ARG E 2 38  ? 129.826 123.673 178.811 1.00 87.24  ? 40  ARG E NH1 1 
ATOM   11078 N NH2 . ARG E 2 38  ? 128.114 123.337 180.294 1.00 87.24  ? 40  ARG E NH2 1 
ATOM   11079 N N   . LEU E 2 39  ? 128.561 129.908 178.532 1.00 90.80  ? 41  LEU E N   1 
ATOM   11080 C CA  . LEU E 2 39  ? 127.412 130.773 178.771 1.00 90.80  ? 41  LEU E CA  1 
ATOM   11081 C C   . LEU E 2 39  ? 127.387 131.268 180.210 1.00 90.80  ? 41  LEU E C   1 
ATOM   11082 O O   . LEU E 2 39  ? 126.910 132.377 180.479 1.00 90.80  ? 41  LEU E O   1 
ATOM   11083 C CB  . LEU E 2 39  ? 126.117 130.032 178.437 1.00 90.80  ? 41  LEU E CB  1 
ATOM   11084 C CG  . LEU E 2 39  ? 125.731 129.930 176.959 1.00 90.80  ? 41  LEU E CG  1 
ATOM   11085 C CD1 . LEU E 2 39  ? 125.935 131.262 176.253 1.00 90.80  ? 41  LEU E CD1 1 
ATOM   11086 C CD2 . LEU E 2 39  ? 126.508 128.821 176.260 1.00 90.80  ? 41  LEU E CD2 1 
ATOM   11087 N N   . LEU E 2 40  ? 127.897 130.464 181.146 1.00 96.49  ? 42  LEU E N   1 
ATOM   11088 C CA  . LEU E 2 40  ? 127.937 130.865 182.547 1.00 96.49  ? 42  LEU E CA  1 
ATOM   11089 C C   . LEU E 2 40  ? 129.058 131.862 182.822 1.00 96.49  ? 42  LEU E C   1 
ATOM   11090 O O   . LEU E 2 40  ? 128.875 132.802 183.603 1.00 96.49  ? 42  LEU E O   1 
ATOM   11091 C CB  . LEU E 2 40  ? 128.089 129.632 183.438 1.00 96.49  ? 42  LEU E CB  1 
ATOM   11092 C CG  . LEU E 2 40  ? 126.977 128.586 183.333 1.00 96.49  ? 42  LEU E CG  1 
ATOM   11093 C CD1 . LEU E 2 40  ? 127.286 127.382 184.211 1.00 96.49  ? 42  LEU E CD1 1 
ATOM   11094 C CD2 . LEU E 2 40  ? 125.624 129.189 183.693 1.00 96.49  ? 42  LEU E CD2 1 
ATOM   11095 N N   . VAL E 2 41  ? 130.224 131.676 182.196 1.00 81.66  ? 43  VAL E N   1 
ATOM   11096 C CA  . VAL E 2 41  ? 131.349 132.563 182.470 1.00 81.66  ? 43  VAL E CA  1 
ATOM   11097 C C   . VAL E 2 41  ? 131.127 133.910 181.787 1.00 81.66  ? 43  VAL E C   1 
ATOM   11098 O O   . VAL E 2 41  ? 130.321 134.051 180.860 1.00 81.66  ? 43  VAL E O   1 
ATOM   11099 C CB  . VAL E 2 41  ? 132.676 131.924 182.025 1.00 81.66  ? 43  VAL E CB  1 
ATOM   11100 C CG1 . VAL E 2 41  ? 132.879 132.102 180.533 1.00 81.66  ? 43  VAL E CG1 1 
ATOM   11101 C CG2 . VAL E 2 41  ? 133.846 132.499 182.811 1.00 81.66  ? 43  VAL E CG2 1 
ATOM   11102 N N   . SER E 2 42  ? 131.858 134.919 182.260 1.00 79.17  ? 44  SER E N   1 
ATOM   11103 C CA  . SER E 2 42  ? 131.718 136.270 181.731 1.00 79.17  ? 44  SER E CA  1 
ATOM   11104 C C   . SER E 2 42  ? 132.377 136.387 180.363 1.00 79.17  ? 44  SER E C   1 
ATOM   11105 O O   . SER E 2 42  ? 133.418 137.037 180.221 1.00 79.17  ? 44  SER E O   1 
ATOM   11106 C CB  . SER E 2 42  ? 132.319 137.290 182.699 1.00 79.17  ? 44  SER E CB  1 
ATOM   11107 O OG  . SER E 2 42  ? 133.723 137.136 182.795 1.00 79.17  ? 44  SER E OG  1 
ATOM   11108 N N   . TYR E 2 43  ? 131.779 135.760 179.354 1.00 66.40  ? 45  TYR E N   1 
ATOM   11109 C CA  . TYR E 2 43  ? 132.267 135.824 177.983 1.00 66.40  ? 45  TYR E CA  1 
ATOM   11110 C C   . TYR E 2 43  ? 131.081 136.077 177.067 1.00 66.40  ? 45  TYR E C   1 
ATOM   11111 O O   . TYR E 2 43  ? 130.140 135.277 177.034 1.00 66.40  ? 45  TYR E O   1 
ATOM   11112 C CB  . TYR E 2 43  ? 132.986 134.530 177.589 1.00 66.40  ? 45  TYR E CB  1 
ATOM   11113 C CG  . TYR E 2 43  ? 133.617 134.576 176.218 1.00 66.40  ? 45  TYR E CG  1 
ATOM   11114 C CD1 . TYR E 2 43  ? 134.910 135.044 176.047 1.00 66.40  ? 45  TYR E CD1 1 
ATOM   11115 C CD2 . TYR E 2 43  ? 132.920 134.156 175.095 1.00 66.40  ? 45  TYR E CD2 1 
ATOM   11116 C CE1 . TYR E 2 43  ? 135.492 135.090 174.800 1.00 66.40  ? 45  TYR E CE1 1 
ATOM   11117 C CE2 . TYR E 2 43  ? 133.494 134.201 173.842 1.00 66.40  ? 45  TYR E CE2 1 
ATOM   11118 C CZ  . TYR E 2 43  ? 134.780 134.669 173.701 1.00 66.40  ? 45  TYR E CZ  1 
ATOM   11119 O OH  . TYR E 2 43  ? 135.358 134.716 172.455 1.00 66.40  ? 45  TYR E OH  1 
ATOM   11120 N N   . ASP E 2 44  ? 131.125 137.181 176.328 1.00 60.19  ? 46  ASP E N   1 
ATOM   11121 C CA  . ASP E 2 44  ? 130.033 137.544 175.433 1.00 60.19  ? 46  ASP E CA  1 
ATOM   11122 C C   . ASP E 2 44  ? 130.463 137.355 173.987 1.00 60.19  ? 46  ASP E C   1 
ATOM   11123 O O   . ASP E 2 44  ? 131.366 138.064 173.518 1.00 60.19  ? 46  ASP E O   1 
ATOM   11124 C CB  . ASP E 2 44  ? 129.594 138.988 175.672 1.00 60.19  ? 46  ASP E CB  1 
ATOM   11125 C CG  . ASP E 2 44  ? 128.156 139.234 175.258 1.00 60.19  ? 46  ASP E CG  1 
ATOM   11126 O OD1 . ASP E 2 44  ? 127.712 138.635 174.256 1.00 60.19  ? 46  ASP E OD1 1 
ATOM   11127 O OD2 . ASP E 2 44  ? 127.466 140.024 175.936 1.00 60.19  ? 46  ASP E OD2 1 
ATOM   11128 N N   . PRO E 2 45  ? 129.859 136.423 173.248 1.00 54.86  ? 47  PRO E N   1 
ATOM   11129 C CA  . PRO E 2 45  ? 130.222 136.260 171.832 1.00 54.86  ? 47  PRO E CA  1 
ATOM   11130 C C   . PRO E 2 45  ? 129.910 137.475 170.982 1.00 54.86  ? 47  PRO E C   1 
ATOM   11131 O O   . PRO E 2 45  ? 130.468 137.603 169.886 1.00 54.86  ? 47  PRO E O   1 
ATOM   11132 C CB  . PRO E 2 45  ? 129.390 135.047 171.393 1.00 54.86  ? 47  PRO E CB  1 
ATOM   11133 C CG  . PRO E 2 45  ? 128.999 134.358 172.661 1.00 54.86  ? 47  PRO E CG  1 
ATOM   11134 C CD  . PRO E 2 45  ? 128.861 135.435 173.684 1.00 54.86  ? 47  PRO E CD  1 
ATOM   11135 N N   . ARG E 2 46  ? 129.038 138.367 171.442 1.00 53.35  ? 48  ARG E N   1 
ATOM   11136 C CA  . ARG E 2 46  ? 128.607 139.509 170.650 1.00 53.35  ? 48  ARG E CA  1 
ATOM   11137 C C   . ARG E 2 46  ? 129.540 140.711 170.765 1.00 53.35  ? 48  ARG E C   1 
ATOM   11138 O O   . ARG E 2 46  ? 129.119 141.830 170.453 1.00 53.35  ? 48  ARG E O   1 
ATOM   11139 C CB  . ARG E 2 46  ? 127.185 139.915 171.047 1.00 53.35  ? 48  ARG E CB  1 
ATOM   11140 C CG  . ARG E 2 46  ? 126.207 138.758 171.118 1.00 53.35  ? 48  ARG E CG  1 
ATOM   11141 C CD  . ARG E 2 46  ? 125.043 139.088 172.030 1.00 53.35  ? 48  ARG E CD  1 
ATOM   11142 N NE  . ARG E 2 46  ? 125.496 139.622 173.308 1.00 53.35  ? 48  ARG E NE  1 
ATOM   11143 C CZ  . ARG E 2 46  ? 124.690 140.021 174.281 1.00 53.35  ? 48  ARG E CZ  1 
ATOM   11144 N NH1 . ARG E 2 46  ? 123.374 139.957 174.159 1.00 53.35  ? 48  ARG E NH1 1 
ATOM   11145 N NH2 . ARG E 2 46  ? 125.216 140.497 175.406 1.00 53.35  ? 48  ARG E NH2 1 
ATOM   11146 N N   . ILE E 2 47  ? 130.782 140.522 171.201 1.00 52.50  ? 49  ILE E N   1 
ATOM   11147 C CA  . ILE E 2 47  ? 131.762 141.599 171.276 1.00 52.50  ? 49  ILE E CA  1 
ATOM   11148 C C   . ILE E 2 47  ? 133.038 141.139 170.588 1.00 52.50  ? 49  ILE E C   1 
ATOM   11149 O O   . ILE E 2 47  ? 133.578 140.079 170.920 1.00 52.50  ? 49  ILE E O   1 
ATOM   11150 C CB  . ILE E 2 47  ? 132.058 142.012 172.729 1.00 52.50  ? 49  ILE E CB  1 
ATOM   11151 C CG1 . ILE E 2 47  ? 130.781 142.471 173.432 1.00 52.50  ? 49  ILE E CG1 1 
ATOM   11152 C CG2 . ILE E 2 47  ? 133.102 143.112 172.760 1.00 52.50  ? 49  ILE E CG2 1 
ATOM   11153 C CD1 . ILE E 2 47  ? 130.164 143.704 172.823 1.00 52.50  ? 49  ILE E CD1 1 
ATOM   11154 N N   . ARG E 2 48  ? 133.518 141.933 169.638 1.00 47.94  ? 50  ARG E N   1 
ATOM   11155 C CA  . ARG E 2 48  ? 134.782 141.630 168.992 1.00 47.94  ? 50  ARG E CA  1 
ATOM   11156 C C   . ARG E 2 48  ? 135.940 141.914 169.949 1.00 47.94  ? 50  ARG E C   1 
ATOM   11157 O O   . ARG E 2 48  ? 135.807 142.719 170.874 1.00 47.94  ? 50  ARG E O   1 
ATOM   11158 C CB  . ARG E 2 48  ? 134.940 142.453 167.718 1.00 47.94  ? 50  ARG E CB  1 
ATOM   11159 C CG  . ARG E 2 48  ? 135.239 143.918 167.960 1.00 47.94  ? 50  ARG E CG  1 
ATOM   11160 C CD  . ARG E 2 48  ? 135.706 144.602 166.690 1.00 47.94  ? 50  ARG E CD  1 
ATOM   11161 N NE  . ARG E 2 48  ? 136.218 145.940 166.955 1.00 47.94  ? 50  ARG E NE  1 
ATOM   11162 C CZ  . ARG E 2 48  ? 137.426 146.196 167.437 1.00 47.94  ? 50  ARG E CZ  1 
ATOM   11163 N NH1 . ARG E 2 48  ? 138.279 145.226 167.715 1.00 47.94  ? 50  ARG E NH1 1 
ATOM   11164 N NH2 . ARG E 2 48  ? 137.786 147.459 167.645 1.00 47.94  ? 50  ARG E NH2 1 
ATOM   11165 N N   . PRO E 2 49  ? 137.081 141.250 169.762 1.00 48.57  ? 51  PRO E N   1 
ATOM   11166 C CA  . PRO E 2 49  ? 138.243 141.545 170.606 1.00 48.57  ? 51  PRO E CA  1 
ATOM   11167 C C   . PRO E 2 49  ? 138.719 142.974 170.406 1.00 48.57  ? 51  PRO E C   1 
ATOM   11168 O O   . PRO E 2 49  ? 138.608 143.542 169.318 1.00 48.57  ? 51  PRO E O   1 
ATOM   11169 C CB  . PRO E 2 49  ? 139.293 140.533 170.134 1.00 48.57  ? 51  PRO E CB  1 
ATOM   11170 C CG  . PRO E 2 49  ? 138.866 140.156 168.763 1.00 48.57  ? 51  PRO E CG  1 
ATOM   11171 C CD  . PRO E 2 49  ? 137.370 140.183 168.790 1.00 48.57  ? 51  PRO E CD  1 
ATOM   11172 N N   . ASN E 2 50  ? 139.255 143.552 171.482 1.00 53.84  ? 52  ASN E N   1 
ATOM   11173 C CA  . ASN E 2 50  ? 139.735 144.934 171.486 1.00 53.84  ? 52  ASN E CA  1 
ATOM   11174 C C   . ASN E 2 50  ? 138.637 145.903 171.049 1.00 53.84  ? 52  ASN E C   1 
ATOM   11175 O O   . ASN E 2 50  ? 138.818 146.715 170.140 1.00 53.84  ? 52  ASN E O   1 
ATOM   11176 C CB  . ASN E 2 50  ? 140.980 145.092 170.611 1.00 53.84  ? 52  ASN E CB  1 
ATOM   11177 C CG  . ASN E 2 50  ? 141.986 143.985 170.825 1.00 53.84  ? 52  ASN E CG  1 
ATOM   11178 O OD1 . ASN E 2 50  ? 142.764 144.014 171.778 1.00 53.84  ? 52  ASN E OD1 1 
ATOM   11179 N ND2 . ASN E 2 50  ? 141.983 143.002 169.934 1.00 53.84  ? 52  ASN E ND2 1 
ATOM   11180 N N   . PHE E 2 51  ? 137.482 145.805 171.703 1.00 61.07  ? 53  PHE E N   1 
ATOM   11181 C CA  . PHE E 2 51  ? 136.402 146.743 171.432 1.00 61.07  ? 53  PHE E CA  1 
ATOM   11182 C C   . PHE E 2 51  ? 136.810 148.145 171.862 1.00 61.07  ? 53  PHE E C   1 
ATOM   11183 O O   . PHE E 2 51  ? 137.476 148.328 172.885 1.00 61.07  ? 53  PHE E O   1 
ATOM   11184 C CB  . PHE E 2 51  ? 135.127 146.315 172.157 1.00 61.07  ? 53  PHE E CB  1 
ATOM   11185 C CG  . PHE E 2 51  ? 133.867 146.810 171.509 1.00 61.07  ? 53  PHE E CG  1 
ATOM   11186 C CD1 . PHE E 2 51  ? 133.902 147.409 170.262 1.00 61.07  ? 53  PHE E CD1 1 
ATOM   11187 C CD2 . PHE E 2 51  ? 132.647 146.671 172.144 1.00 61.07  ? 53  PHE E CD2 1 
ATOM   11188 C CE1 . PHE E 2 51  ? 132.745 147.865 169.664 1.00 61.07  ? 53  PHE E CE1 1 
ATOM   11189 C CE2 . PHE E 2 51  ? 131.486 147.124 171.550 1.00 61.07  ? 53  PHE E CE2 1 
ATOM   11190 C CZ  . PHE E 2 51  ? 131.535 147.721 170.308 1.00 61.07  ? 53  PHE E CZ  1 
ATOM   11191 N N   . LYS E 2 52  ? 136.402 149.139 171.070 1.00 64.66  ? 54  LYS E N   1 
ATOM   11192 C CA  . LYS E 2 52  ? 136.802 150.530 171.281 1.00 64.66  ? 54  LYS E CA  1 
ATOM   11193 C C   . LYS E 2 52  ? 138.323 150.661 171.330 1.00 64.66  ? 54  LYS E C   1 
ATOM   11194 O O   . LYS E 2 52  ? 138.879 151.361 172.178 1.00 64.66  ? 54  LYS E O   1 
ATOM   11195 C CB  . LYS E 2 52  ? 136.163 151.108 172.546 1.00 64.66  ? 54  LYS E CB  1 
ATOM   11196 C CG  . LYS E 2 52  ? 134.649 151.224 172.483 1.00 64.66  ? 54  LYS E CG  1 
ATOM   11197 C CD  . LYS E 2 52  ? 134.200 151.895 171.197 1.00 64.66  ? 54  LYS E CD  1 
ATOM   11198 C CE  . LYS E 2 52  ? 132.690 151.837 171.048 1.00 64.66  ? 54  LYS E CE  1 
ATOM   11199 N NZ  . LYS E 2 52  ? 132.004 151.900 172.368 1.00 64.66  ? 54  LYS E NZ  1 
ATOM   11200 N N   . GLY E 2 53  ? 138.999 149.974 170.421 1.00 59.99  ? 55  GLY E N   1 
ATOM   11201 C CA  . GLY E 2 53  ? 140.450 149.977 170.364 1.00 59.99  ? 55  GLY E CA  1 
ATOM   11202 C C   . GLY E 2 53  ? 140.946 149.673 168.969 1.00 59.99  ? 55  GLY E C   1 
ATOM   11203 O O   . GLY E 2 53  ? 140.250 149.920 167.978 1.00 59.99  ? 55  GLY E O   1 
ATOM   11204 N N   . ILE E 2 54  ? 142.158 149.132 168.893 1.00 51.27  ? 56  ILE E N   1 
ATOM   11205 C CA  . ILE E 2 54  ? 142.820 148.843 167.622 1.00 51.27  ? 56  ILE E CA  1 
ATOM   11206 C C   . ILE E 2 54  ? 142.073 147.732 166.890 1.00 51.27  ? 56  ILE E C   1 
ATOM   11207 O O   . ILE E 2 54  ? 141.539 146.814 167.528 1.00 51.27  ? 56  ILE E O   1 
ATOM   11208 C CB  . ILE E 2 54  ? 144.315 148.540 167.858 1.00 51.27  ? 56  ILE E CB  1 
ATOM   11209 C CG1 . ILE E 2 54  ? 144.585 147.160 168.487 1.00 51.27  ? 56  ILE E CG1 1 
ATOM   11210 C CG2 . ILE E 2 54  ? 144.941 149.625 168.721 1.00 51.27  ? 56  ILE E CG2 1 
ATOM   11211 C CD1 . ILE E 2 54  ? 144.593 145.965 167.552 1.00 51.27  ? 56  ILE E CD1 1 
ATOM   11212 N N   . PRO E 2 55  ? 141.975 147.796 165.564 1.00 45.05  ? 57  PRO E N   1 
ATOM   11213 C CA  . PRO E 2 55  ? 141.261 146.751 164.823 1.00 45.05  ? 57  PRO E CA  1 
ATOM   11214 C C   . PRO E 2 55  ? 142.007 145.428 164.834 1.00 45.05  ? 57  PRO E C   1 
ATOM   11215 O O   . PRO E 2 55  ? 143.238 145.381 164.815 1.00 45.05  ? 57  PRO E O   1 
ATOM   11216 C CB  . PRO E 2 55  ? 141.173 147.321 163.404 1.00 45.05  ? 57  PRO E CB  1 
ATOM   11217 C CG  . PRO E 2 55  ? 142.308 148.274 163.315 1.00 45.05  ? 57  PRO E CG  1 
ATOM   11218 C CD  . PRO E 2 55  ? 142.449 148.874 164.680 1.00 45.05  ? 57  PRO E CD  1 
ATOM   11219 N N   . VAL E 2 56  ? 141.238 144.345 164.830 1.00 39.15  ? 58  VAL E N   1 
ATOM   11220 C CA  . VAL E 2 56  ? 141.805 143.002 164.851 1.00 39.15  ? 58  VAL E CA  1 
ATOM   11221 C C   . VAL E 2 56  ? 142.157 142.584 163.431 1.00 39.15  ? 58  VAL E C   1 
ATOM   11222 O O   . VAL E 2 56  ? 141.317 142.642 162.527 1.00 39.15  ? 58  VAL E O   1 
ATOM   11223 C CB  . VAL E 2 56  ? 140.824 142.011 165.495 1.00 39.15  ? 58  VAL E CB  1 
ATOM   11224 C CG1 . VAL E 2 56  ? 139.404 142.324 165.070 1.00 39.15  ? 58  VAL E CG1 1 
ATOM   11225 C CG2 . VAL E 2 56  ? 141.184 140.590 165.110 1.00 39.15  ? 58  VAL E CG2 1 
ATOM   11226 N N   . ASP E 2 57  ? 143.402 142.165 163.231 1.00 32.48  ? 59  ASP E N   1 
ATOM   11227 C CA  . ASP E 2 57  ? 143.880 141.714 161.932 1.00 32.48  ? 59  ASP E CA  1 
ATOM   11228 C C   . ASP E 2 57  ? 143.795 140.197 161.861 1.00 32.48  ? 59  ASP E C   1 
ATOM   11229 O O   . ASP E 2 57  ? 144.187 139.505 162.805 1.00 32.48  ? 59  ASP E O   1 
ATOM   11230 C CB  . ASP E 2 57  ? 145.315 142.179 161.687 1.00 32.48  ? 59  ASP E CB  1 
ATOM   11231 C CG  . ASP E 2 57  ? 146.150 142.172 162.949 1.00 32.48  ? 59  ASP E CG  1 
ATOM   11232 O OD1 . ASP E 2 57  ? 145.696 141.598 163.961 1.00 32.48  ? 59  ASP E OD1 1 
ATOM   11233 O OD2 . ASP E 2 57  ? 147.260 142.745 162.930 1.00 32.48  ? 59  ASP E OD2 1 
ATOM   11234 N N   . VAL E 2 58  ? 143.288 139.687 160.744 1.00 25.72  ? 60  VAL E N   1 
ATOM   11235 C CA  . VAL E 2 58  ? 143.054 138.262 160.553 1.00 25.72  ? 60  VAL E CA  1 
ATOM   11236 C C   . VAL E 2 58  ? 144.014 137.751 159.491 1.00 25.72  ? 60  VAL E C   1 
ATOM   11237 O O   . VAL E 2 58  ? 144.043 138.272 158.370 1.00 25.72  ? 60  VAL E O   1 
ATOM   11238 C CB  . VAL E 2 58  ? 141.597 137.987 160.149 1.00 25.72  ? 60  VAL E CB  1 
ATOM   11239 C CG1 . VAL E 2 58  ? 141.438 136.554 159.697 1.00 25.72  ? 60  VAL E CG1 1 
ATOM   11240 C CG2 . VAL E 2 58  ? 140.666 138.294 161.302 1.00 25.72  ? 60  VAL E CG2 1 
ATOM   11241 N N   . VAL E 2 59  ? 144.793 136.733 159.839 1.00 29.13  ? 61  VAL E N   1 
ATOM   11242 C CA  . VAL E 2 59  ? 145.720 136.108 158.902 1.00 29.13  ? 61  VAL E CA  1 
ATOM   11243 C C   . VAL E 2 59  ? 144.995 134.965 158.207 1.00 29.13  ? 61  VAL E C   1 
ATOM   11244 O O   . VAL E 2 59  ? 144.635 133.971 158.844 1.00 29.13  ? 61  VAL E O   1 
ATOM   11245 C CB  . VAL E 2 59  ? 146.981 135.606 159.619 1.00 29.13  ? 61  VAL E CB  1 
ATOM   11246 C CG1 . VAL E 2 59  ? 147.874 134.859 158.648 1.00 29.13  ? 61  VAL E CG1 1 
ATOM   11247 C CG2 . VAL E 2 59  ? 147.728 136.767 160.250 1.00 29.13  ? 61  VAL E CG2 1 
ATOM   11248 N N   . VAL E 2 60  ? 144.791 135.097 156.900 1.00 27.71  ? 62  VAL E N   1 
ATOM   11249 C CA  . VAL E 2 60  ? 143.979 134.163 156.130 1.00 27.71  ? 62  VAL E CA  1 
ATOM   11250 C C   . VAL E 2 60  ? 144.894 133.254 155.325 1.00 27.71  ? 62  VAL E C   1 
ATOM   11251 O O   . VAL E 2 60  ? 145.837 133.722 154.677 1.00 27.71  ? 62  VAL E O   1 
ATOM   11252 C CB  . VAL E 2 60  ? 143.000 134.909 155.210 1.00 27.71  ? 62  VAL E CB  1 
ATOM   11253 C CG1 . VAL E 2 60  ? 142.241 133.930 154.346 1.00 27.71  ? 62  VAL E CG1 1 
ATOM   11254 C CG2 . VAL E 2 60  ? 142.041 135.736 156.033 1.00 27.71  ? 62  VAL E CG2 1 
ATOM   11255 N N   . ASN E 2 61  ? 144.618 131.954 155.369 1.00 39.78  ? 63  ASN E N   1 
ATOM   11256 C CA  . ASN E 2 61  ? 145.372 130.947 154.638 1.00 39.78  ? 63  ASN E CA  1 
ATOM   11257 C C   . ASN E 2 61  ? 144.393 129.995 153.970 1.00 39.78  ? 63  ASN E C   1 
ATOM   11258 O O   . ASN E 2 61  ? 143.418 129.563 154.590 1.00 39.78  ? 63  ASN E O   1 
ATOM   11259 C CB  . ASN E 2 61  ? 146.313 130.186 155.576 1.00 39.78  ? 63  ASN E CB  1 
ATOM   11260 C CG  . ASN E 2 61  ? 147.102 129.106 154.870 1.00 39.78  ? 63  ASN E CG  1 
ATOM   11261 O OD1 . ASN E 2 61  ? 147.058 128.981 153.649 1.00 39.78  ? 63  ASN E OD1 1 
ATOM   11262 N ND2 . ASN E 2 61  ? 147.837 128.318 155.642 1.00 39.78  ? 63  ASN E ND2 1 
ATOM   11263 N N   . ILE E 2 62  ? 144.655 129.665 152.708 1.00 47.29  ? 64  ILE E N   1 
ATOM   11264 C CA  . ILE E 2 62  ? 143.753 128.856 151.899 1.00 47.29  ? 64  ILE E CA  1 
ATOM   11265 C C   . ILE E 2 62  ? 144.508 127.637 151.393 1.00 47.29  ? 64  ILE E C   1 
ATOM   11266 O O   . ILE E 2 62  ? 145.617 127.766 150.863 1.00 47.29  ? 64  ILE E O   1 
ATOM   11267 C CB  . ILE E 2 62  ? 143.175 129.660 150.721 1.00 47.29  ? 64  ILE E CB  1 
ATOM   11268 C CG1 . ILE E 2 62  ? 142.037 130.557 151.194 1.00 47.29  ? 64  ILE E CG1 1 
ATOM   11269 C CG2 . ILE E 2 62  ? 142.684 128.734 149.628 1.00 47.29  ? 64  ILE E CG2 1 
ATOM   11270 C CD1 . ILE E 2 62  ? 141.296 131.227 150.068 1.00 47.29  ? 64  ILE E CD1 1 
ATOM   11271 N N   . PHE E 2 63  ? 143.911 126.460 151.556 1.00 42.73  ? 65  PHE E N   1 
ATOM   11272 C CA  . PHE E 2 63  ? 144.429 125.222 150.987 1.00 42.73  ? 65  PHE E CA  1 
ATOM   11273 C C   . PHE E 2 63  ? 143.387 124.686 150.021 1.00 42.73  ? 65  PHE E C   1 
ATOM   11274 O O   . PHE E 2 63  ? 142.234 124.476 150.407 1.00 42.73  ? 65  PHE E O   1 
ATOM   11275 C CB  . PHE E 2 63  ? 144.736 124.200 152.082 1.00 42.73  ? 65  PHE E CB  1 
ATOM   11276 C CG  . PHE E 2 63  ? 145.096 122.836 151.564 1.00 42.73  ? 65  PHE E CG  1 
ATOM   11277 C CD1 . PHE E 2 63  ? 146.407 122.520 151.263 1.00 42.73  ? 65  PHE E CD1 1 
ATOM   11278 C CD2 . PHE E 2 63  ? 144.127 121.863 151.396 1.00 42.73  ? 65  PHE E CD2 1 
ATOM   11279 C CE1 . PHE E 2 63  ? 146.743 121.265 150.795 1.00 42.73  ? 65  PHE E CE1 1 
ATOM   11280 C CE2 . PHE E 2 63  ? 144.458 120.609 150.927 1.00 42.73  ? 65  PHE E CE2 1 
ATOM   11281 C CZ  . PHE E 2 63  ? 145.768 120.310 150.627 1.00 42.73  ? 65  PHE E CZ  1 
ATOM   11282 N N   . ILE E 2 64  ? 143.788 124.461 148.774 1.00 34.70  ? 66  ILE E N   1 
ATOM   11283 C CA  . ILE E 2 64  ? 142.865 124.030 147.730 1.00 34.70  ? 66  ILE E CA  1 
ATOM   11284 C C   . ILE E 2 64  ? 142.887 122.508 147.674 1.00 34.70  ? 66  ILE E C   1 
ATOM   11285 O O   . ILE E 2 64  ? 143.872 121.906 147.243 1.00 34.70  ? 66  ILE E O   1 
ATOM   11286 C CB  . ILE E 2 64  ? 143.224 124.643 146.373 1.00 34.70  ? 66  ILE E CB  1 
ATOM   11287 C CG1 . ILE E 2 64  ? 142.873 126.129 146.362 1.00 34.70  ? 66  ILE E CG1 1 
ATOM   11288 C CG2 . ILE E 2 64  ? 142.491 123.922 145.260 1.00 34.70  ? 66  ILE E CG2 1 
ATOM   11289 C CD1 . ILE E 2 64  ? 142.732 126.713 144.981 1.00 34.70  ? 66  ILE E CD1 1 
ATOM   11290 N N   . ASN E 2 65  ? 141.799 121.884 148.123 1.00 33.61  ? 67  ASN E N   1 
ATOM   11291 C CA  . ASN E 2 65  ? 141.714 120.429 148.097 1.00 33.61  ? 67  ASN E CA  1 
ATOM   11292 C C   . ASN E 2 65  ? 141.421 119.905 146.698 1.00 33.61  ? 67  ASN E C   1 
ATOM   11293 O O   . ASN E 2 65  ? 141.967 118.873 146.294 1.00 33.61  ? 67  ASN E O   1 
ATOM   11294 C CB  . ASN E 2 65  ? 140.645 119.948 149.077 1.00 33.61  ? 67  ASN E CB  1 
ATOM   11295 C CG  . ASN E 2 65  ? 140.568 118.440 149.156 1.00 33.61  ? 67  ASN E CG  1 
ATOM   11296 O OD1 . ASN E 2 65  ? 141.551 117.743 148.913 1.00 33.61  ? 67  ASN E OD1 1 
ATOM   11297 N ND2 . ASN E 2 65  ? 139.393 117.927 149.493 1.00 33.61  ? 67  ASN E ND2 1 
ATOM   11298 N N   . SER E 2 66  ? 140.565 120.593 145.948 1.00 34.60  ? 68  SER E N   1 
ATOM   11299 C CA  . SER E 2 66  ? 140.193 120.147 144.614 1.00 34.60  ? 68  SER E CA  1 
ATOM   11300 C C   . SER E 2 66  ? 139.791 121.349 143.779 1.00 34.60  ? 68  SER E C   1 
ATOM   11301 O O   . SER E 2 66  ? 139.086 122.239 144.257 1.00 34.60  ? 68  SER E O   1 
ATOM   11302 C CB  . SER E 2 66  ? 139.045 119.134 144.656 1.00 34.60  ? 68  SER E CB  1 
ATOM   11303 O OG  . SER E 2 66  ? 137.792 119.793 144.669 1.00 34.60  ? 68  SER E OG  1 
ATOM   11304 N N   . PHE E 2 67  ? 140.238 121.359 142.530 1.00 38.48  ? 69  PHE E N   1 
ATOM   11305 C CA  . PHE E 2 67  ? 139.992 122.450 141.602 1.00 38.48  ? 69  PHE E CA  1 
ATOM   11306 C C   . PHE E 2 67  ? 139.522 121.860 140.283 1.00 38.48  ? 69  PHE E C   1 
ATOM   11307 O O   . PHE E 2 67  ? 139.966 120.777 139.891 1.00 38.48  ? 69  PHE E O   1 
ATOM   11308 C CB  . PHE E 2 67  ? 141.270 123.279 141.400 1.00 38.48  ? 69  PHE E CB  1 
ATOM   11309 C CG  . PHE E 2 67  ? 141.041 124.633 140.793 1.00 38.48  ? 69  PHE E CG  1 
ATOM   11310 C CD1 . PHE E 2 67  ? 140.773 124.771 139.446 1.00 38.48  ? 69  PHE E CD1 1 
ATOM   11311 C CD2 . PHE E 2 67  ? 141.124 125.771 141.571 1.00 38.48  ? 69  PHE E CD2 1 
ATOM   11312 C CE1 . PHE E 2 67  ? 140.572 126.014 138.891 1.00 38.48  ? 69  PHE E CE1 1 
ATOM   11313 C CE2 . PHE E 2 67  ? 140.925 127.017 141.020 1.00 38.48  ? 69  PHE E CE2 1 
ATOM   11314 C CZ  . PHE E 2 67  ? 140.649 127.137 139.679 1.00 38.48  ? 69  PHE E CZ  1 
ATOM   11315 N N   . GLY E 2 68  ? 138.621 122.553 139.610 1.00 40.12  ? 70  GLY E N   1 
ATOM   11316 C CA  . GLY E 2 68  ? 138.229 122.148 138.279 1.00 40.12  ? 70  GLY E CA  1 
ATOM   11317 C C   . GLY E 2 68  ? 136.751 122.386 138.049 1.00 40.12  ? 70  GLY E C   1 
ATOM   11318 O O   . GLY E 2 68  ? 136.138 123.233 138.690 1.00 40.12  ? 70  GLY E O   1 
ATOM   11319 N N   . SER E 2 69  ? 136.208 121.608 137.110 1.00 48.03  ? 71  SER E N   1 
ATOM   11320 C CA  . SER E 2 69  ? 134.812 121.719 136.687 1.00 48.03  ? 71  SER E CA  1 
ATOM   11321 C C   . SER E 2 69  ? 134.506 123.116 136.159 1.00 48.03  ? 71  SER E C   1 
ATOM   11322 O O   . SER E 2 69  ? 133.400 123.634 136.324 1.00 48.03  ? 71  SER E O   1 
ATOM   11323 C CB  . SER E 2 69  ? 133.855 121.343 137.820 1.00 48.03  ? 71  SER E CB  1 
ATOM   11324 O OG  . SER E 2 69  ? 132.513 121.620 137.461 1.00 48.03  ? 71  SER E OG  1 
ATOM   11325 N N   . ILE E 2 70  ? 135.491 123.730 135.511 1.00 44.16  ? 72  ILE E N   1 
ATOM   11326 C CA  . ILE E 2 70  ? 135.325 125.073 134.969 1.00 44.16  ? 72  ILE E CA  1 
ATOM   11327 C C   . ILE E 2 70  ? 134.469 124.987 133.712 1.00 44.16  ? 72  ILE E C   1 
ATOM   11328 O O   . ILE E 2 70  ? 134.789 124.244 132.779 1.00 44.16  ? 72  ILE E O   1 
ATOM   11329 C CB  . ILE E 2 70  ? 136.684 125.725 134.678 1.00 44.16  ? 72  ILE E CB  1 
ATOM   11330 C CG1 . ILE E 2 70  ? 136.515 126.917 133.734 1.00 44.16  ? 72  ILE E CG1 1 
ATOM   11331 C CG2 . ILE E 2 70  ? 137.656 124.705 134.113 1.00 44.16  ? 72  ILE E CG2 1 
ATOM   11332 C CD1 . ILE E 2 70  ? 137.765 127.748 133.573 1.00 44.16  ? 72  ILE E CD1 1 
ATOM   11333 N N   . GLN E 2 71  ? 133.375 125.742 133.690 1.00 49.91  ? 73  GLN E N   1 
ATOM   11334 C CA  . GLN E 2 71  ? 132.414 125.712 132.597 1.00 49.91  ? 73  GLN E CA  1 
ATOM   11335 C C   . GLN E 2 71  ? 132.442 127.043 131.863 1.00 49.91  ? 73  GLN E C   1 
ATOM   11336 O O   . GLN E 2 71  ? 132.330 128.103 132.487 1.00 49.91  ? 73  GLN E O   1 
ATOM   11337 C CB  . GLN E 2 71  ? 131.006 125.426 133.118 1.00 49.91  ? 73  GLN E CB  1 
ATOM   11338 C CG  . GLN E 2 71  ? 130.944 124.308 134.142 1.00 49.91  ? 73  GLN E CG  1 
ATOM   11339 C CD  . GLN E 2 71  ? 129.768 124.448 135.086 1.00 49.91  ? 73  GLN E CD  1 
ATOM   11340 O OE1 . GLN E 2 71  ? 129.886 124.199 136.286 1.00 49.91  ? 73  GLN E OE1 1 
ATOM   11341 N NE2 . GLN E 2 71  ? 128.622 124.848 134.547 1.00 49.91  ? 73  GLN E NE2 1 
ATOM   11342 N N   . GLU E 2 72  ? 132.594 126.985 130.540 1.00 56.36  ? 74  GLU E N   1 
ATOM   11343 C CA  . GLU E 2 72  ? 132.647 128.207 129.746 1.00 56.36  ? 74  GLU E CA  1 
ATOM   11344 C C   . GLU E 2 72  ? 131.263 128.814 129.549 1.00 56.36  ? 74  GLU E C   1 
ATOM   11345 O O   . GLU E 2 72  ? 131.124 130.041 129.504 1.00 56.36  ? 74  GLU E O   1 
ATOM   11346 C CB  . GLU E 2 72  ? 133.302 127.925 128.393 1.00 56.36  ? 74  GLU E CB  1 
ATOM   11347 N N   . THR E 2 73  ? 130.234 127.973 129.424 1.00 55.70  ? 75  THR E N   1 
ATOM   11348 C CA  . THR E 2 73  ? 128.891 128.481 129.159 1.00 55.70  ? 75  THR E CA  1 
ATOM   11349 C C   . THR E 2 73  ? 128.363 129.313 130.321 1.00 55.70  ? 75  THR E C   1 
ATOM   11350 O O   . THR E 2 73  ? 127.760 130.371 130.110 1.00 55.70  ? 75  THR E O   1 
ATOM   11351 C CB  . THR E 2 73  ? 127.942 127.324 128.854 1.00 55.70  ? 75  THR E CB  1 
ATOM   11352 O OG1 . THR E 2 73  ? 126.590 127.742 129.077 1.00 55.70  ? 75  THR E OG1 1 
ATOM   11353 C CG2 . THR E 2 73  ? 128.258 126.124 129.734 1.00 55.70  ? 75  THR E CG2 1 
ATOM   11354 N N   . THR E 2 74  ? 128.572 128.853 131.553 1.00 49.31  ? 76  THR E N   1 
ATOM   11355 C CA  . THR E 2 74  ? 128.102 129.575 132.727 1.00 49.31  ? 76  THR E CA  1 
ATOM   11356 C C   . THR E 2 74  ? 129.160 130.514 133.297 1.00 49.31  ? 76  THR E C   1 
ATOM   11357 O O   . THR E 2 74  ? 128.827 131.385 134.110 1.00 49.31  ? 76  THR E O   1 
ATOM   11358 C CB  . THR E 2 74  ? 127.644 128.574 133.796 1.00 49.31  ? 76  THR E CB  1 
ATOM   11359 O OG1 . THR E 2 74  ? 126.804 127.587 133.188 1.00 49.31  ? 76  THR E OG1 1 
ATOM   11360 C CG2 . THR E 2 74  ? 126.844 129.265 134.887 1.00 49.31  ? 76  THR E CG2 1 
ATOM   11361 N N   . MET E 2 75  ? 130.417 130.368 132.871 1.00 48.20  ? 77  MET E N   1 
ATOM   11362 C CA  . MET E 2 75  ? 131.515 131.243 133.286 1.00 48.20  ? 77  MET E CA  1 
ATOM   11363 C C   . MET E 2 75  ? 131.748 131.168 134.793 1.00 48.20  ? 77  MET E C   1 
ATOM   11364 O O   . MET E 2 75  ? 131.860 132.184 135.480 1.00 48.20  ? 77  MET E O   1 
ATOM   11365 C CB  . MET E 2 75  ? 131.270 132.689 132.844 1.00 48.20  ? 77  MET E CB  1 
ATOM   11366 C CG  . MET E 2 75  ? 130.866 132.841 131.390 1.00 48.20  ? 77  MET E CG  1 
ATOM   11367 S SD  . MET E 2 75  ? 130.860 134.563 130.858 1.00 48.20  ? 77  MET E SD  1 
ATOM   11368 C CE  . MET E 2 75  ? 130.035 134.427 129.275 1.00 48.20  ? 77  MET E CE  1 
ATOM   11369 N N   . ASP E 2 76  ? 131.827 129.944 135.310 1.00 43.30  ? 78  ASP E N   1 
ATOM   11370 C CA  . ASP E 2 76  ? 132.087 129.745 136.727 1.00 43.30  ? 78  ASP E CA  1 
ATOM   11371 C C   . ASP E 2 76  ? 132.778 128.406 136.931 1.00 43.30  ? 78  ASP E C   1 
ATOM   11372 O O   . ASP E 2 76  ? 132.693 127.506 136.093 1.00 43.30  ? 78  ASP E O   1 
ATOM   11373 C CB  . ASP E 2 76  ? 130.798 129.819 137.553 1.00 43.30  ? 78  ASP E CB  1 
ATOM   11374 C CG  . ASP E 2 76  ? 129.709 128.915 137.020 1.00 43.30  ? 78  ASP E CG  1 
ATOM   11375 O OD1 . ASP E 2 76  ? 129.932 128.270 135.976 1.00 43.30  ? 78  ASP E OD1 1 
ATOM   11376 O OD2 . ASP E 2 76  ? 128.629 128.851 137.645 1.00 43.30  ? 78  ASP E OD2 1 
ATOM   11377 N N   . TYR E 2 77  ? 133.462 128.285 138.065 1.00 35.44  ? 79  TYR E N   1 
ATOM   11378 C CA  . TYR E 2 77  ? 134.202 127.079 138.401 1.00 35.44  ? 79  TYR E CA  1 
ATOM   11379 C C   . TYR E 2 77  ? 133.990 126.752 139.871 1.00 35.44  ? 79  TYR E C   1 
ATOM   11380 O O   . TYR E 2 77  ? 133.656 127.621 140.678 1.00 35.44  ? 79  TYR E O   1 
ATOM   11381 C CB  . TYR E 2 77  ? 135.698 127.229 138.095 1.00 35.44  ? 79  TYR E CB  1 
ATOM   11382 C CG  . TYR E 2 77  ? 136.389 128.330 138.862 1.00 35.44  ? 79  TYR E CG  1 
ATOM   11383 C CD1 . TYR E 2 77  ? 136.176 129.661 138.549 1.00 35.44  ? 79  TYR E CD1 1 
ATOM   11384 C CD2 . TYR E 2 77  ? 137.269 128.036 139.890 1.00 35.44  ? 79  TYR E CD2 1 
ATOM   11385 C CE1 . TYR E 2 77  ? 136.809 130.665 139.244 1.00 35.44  ? 79  TYR E CE1 1 
ATOM   11386 C CE2 . TYR E 2 77  ? 137.908 129.035 140.590 1.00 35.44  ? 79  TYR E CE2 1 
ATOM   11387 C CZ  . TYR E 2 77  ? 137.675 130.347 140.263 1.00 35.44  ? 79  TYR E CZ  1 
ATOM   11388 O OH  . TYR E 2 77  ? 138.309 131.348 140.957 1.00 35.44  ? 79  TYR E OH  1 
ATOM   11389 N N   . ARG E 2 78  ? 134.182 125.481 140.211 1.00 38.43  ? 80  ARG E N   1 
ATOM   11390 C CA  . ARG E 2 78  ? 133.978 124.983 141.564 1.00 38.43  ? 80  ARG E CA  1 
ATOM   11391 C C   . ARG E 2 78  ? 135.322 124.632 142.182 1.00 38.43  ? 80  ARG E C   1 
ATOM   11392 O O   . ARG E 2 78  ? 136.156 123.990 141.536 1.00 38.43  ? 80  ARG E O   1 
ATOM   11393 C CB  . ARG E 2 78  ? 133.059 123.761 141.563 1.00 38.43  ? 80  ARG E CB  1 
ATOM   11394 C CG  . ARG E 2 78  ? 131.582 124.102 141.465 1.00 38.43  ? 80  ARG E CG  1 
ATOM   11395 C CD  . ARG E 2 78  ? 130.712 122.876 141.675 1.00 38.43  ? 80  ARG E CD  1 
ATOM   11396 N NE  . ARG E 2 78  ? 131.084 122.144 142.878 1.00 38.43  ? 80  ARG E NE  1 
ATOM   11397 C CZ  . ARG E 2 78  ? 130.530 122.331 144.067 1.00 38.43  ? 80  ARG E CZ  1 
ATOM   11398 N NH1 . ARG E 2 78  ? 129.572 123.224 144.250 1.00 38.43  ? 80  ARG E NH1 1 
ATOM   11399 N NH2 . ARG E 2 78  ? 130.949 121.604 145.099 1.00 38.43  ? 80  ARG E NH2 1 
ATOM   11400 N N   . VAL E 2 79  ? 135.531 125.051 143.427 1.00 47.29  ? 81  VAL E N   1 
ATOM   11401 C CA  . VAL E 2 79  ? 136.788 124.824 144.129 1.00 47.29  ? 81  VAL E CA  1 
ATOM   11402 C C   . VAL E 2 79  ? 136.487 124.403 145.561 1.00 47.29  ? 81  VAL E C   1 
ATOM   11403 O O   . VAL E 2 79  ? 135.673 125.036 146.239 1.00 47.29  ? 81  VAL E O   1 
ATOM   11404 C CB  . VAL E 2 79  ? 137.680 126.080 144.103 1.00 47.29  ? 81  VAL E CB  1 
ATOM   11405 C CG1 . VAL E 2 79  ? 136.841 127.319 144.289 1.00 47.29  ? 81  VAL E CG1 1 
ATOM   11406 C CG2 . VAL E 2 79  ? 138.746 126.001 145.172 1.00 47.29  ? 81  VAL E CG2 1 
ATOM   11407 N N   . ASN E 2 80  ? 137.133 123.329 146.016 1.00 43.21  ? 82  ASN E N   1 
ATOM   11408 C CA  . ASN E 2 80  ? 137.042 122.867 147.398 1.00 43.21  ? 82  ASN E CA  1 
ATOM   11409 C C   . ASN E 2 80  ? 138.255 123.396 148.152 1.00 43.21  ? 82  ASN E C   1 
ATOM   11410 O O   . ASN E 2 80  ? 139.386 122.984 147.882 1.00 43.21  ? 82  ASN E O   1 
ATOM   11411 C CB  . ASN E 2 80  ? 136.988 121.344 147.465 1.00 43.21  ? 82  ASN E CB  1 
ATOM   11412 C CG  . ASN E 2 80  ? 135.578 120.814 147.503 1.00 43.21  ? 82  ASN E CG  1 
ATOM   11413 O OD1 . ASN E 2 80  ? 134.616 121.573 147.406 1.00 43.21  ? 82  ASN E OD1 1 
ATOM   11414 N ND2 . ASN E 2 80  ? 135.443 119.502 147.648 1.00 43.21  ? 82  ASN E ND2 1 
ATOM   11415 N N   . ILE E 2 81  ? 138.023 124.292 149.105 1.00 47.29  ? 83  ILE E N   1 
ATOM   11416 C CA  . ILE E 2 81  ? 139.096 125.036 149.750 1.00 47.29  ? 83  ILE E CA  1 
ATOM   11417 C C   . ILE E 2 81  ? 138.981 124.873 151.258 1.00 47.29  ? 83  ILE E C   1 
ATOM   11418 O O   . ILE E 2 81  ? 137.881 124.954 151.814 1.00 47.29  ? 83  ILE E O   1 
ATOM   11419 C CB  . ILE E 2 81  ? 139.065 126.524 149.344 1.00 47.29  ? 83  ILE E CB  1 
ATOM   11420 C CG1 . ILE E 2 81  ? 139.263 127.443 150.551 1.00 47.29  ? 83  ILE E CG1 1 
ATOM   11421 C CG2 . ILE E 2 81  ? 137.775 126.844 148.612 1.00 47.29  ? 83  ILE E CG2 1 
ATOM   11422 C CD1 . ILE E 2 81  ? 138.006 128.161 151.000 1.00 47.29  ? 83  ILE E CD1 1 
ATOM   11423 N N   . PHE E 2 82  ? 140.113 124.617 151.912 1.00 47.29  ? 84  PHE E N   1 
ATOM   11424 C CA  . PHE E 2 82  ? 140.193 124.581 153.371 1.00 47.29  ? 84  PHE E CA  1 
ATOM   11425 C C   . PHE E 2 82  ? 140.590 125.968 153.852 1.00 47.29  ? 84  PHE E C   1 
ATOM   11426 O O   . PHE E 2 82  ? 141.774 126.258 154.026 1.00 47.29  ? 84  PHE E O   1 
ATOM   11427 C CB  . PHE E 2 82  ? 141.207 123.546 153.843 1.00 47.29  ? 84  PHE E CB  1 
ATOM   11428 C CG  . PHE E 2 82  ? 140.784 122.128 153.629 1.00 47.29  ? 84  PHE E CG  1 
ATOM   11429 C CD1 . PHE E 2 82  ? 139.501 121.823 153.230 1.00 47.29  ? 84  PHE E CD1 1 
ATOM   11430 C CD2 . PHE E 2 82  ? 141.678 121.096 153.836 1.00 47.29  ? 84  PHE E CD2 1 
ATOM   11431 C CE1 . PHE E 2 82  ? 139.121 120.516 153.037 1.00 47.29  ? 84  PHE E CE1 1 
ATOM   11432 C CE2 . PHE E 2 82  ? 141.303 119.790 153.644 1.00 47.29  ? 84  PHE E CE2 1 
ATOM   11433 C CZ  . PHE E 2 82  ? 140.022 119.499 153.245 1.00 47.29  ? 84  PHE E CZ  1 
ATOM   11434 N N   . LEU E 2 83  ? 139.607 126.828 154.081 1.00 47.29  ? 85  LEU E N   1 
ATOM   11435 C CA  . LEU E 2 83  ? 139.894 128.182 154.530 1.00 47.29  ? 85  LEU E CA  1 
ATOM   11436 C C   . LEU E 2 83  ? 140.422 128.151 155.956 1.00 47.29  ? 85  LEU E C   1 
ATOM   11437 O O   . LEU E 2 83  ? 139.842 127.496 156.825 1.00 47.29  ? 85  LEU E O   1 
ATOM   11438 C CB  . LEU E 2 83  ? 138.642 129.048 154.449 1.00 47.29  ? 85  LEU E CB  1 
ATOM   11439 C CG  . LEU E 2 83  ? 138.805 130.468 154.974 1.00 47.29  ? 85  LEU E CG  1 
ATOM   11440 C CD1 . LEU E 2 83  ? 138.273 131.447 153.959 1.00 47.29  ? 85  LEU E CD1 1 
ATOM   11441 C CD2 . LEU E 2 83  ? 138.086 130.629 156.295 1.00 47.29  ? 85  LEU E CD2 1 
ATOM   11442 N N   . ARG E 2 84  ? 141.525 128.854 156.196 1.00 37.00  ? 86  ARG E N   1 
ATOM   11443 C CA  . ARG E 2 84  ? 142.142 128.920 157.513 1.00 37.00  ? 86  ARG E CA  1 
ATOM   11444 C C   . ARG E 2 84  ? 142.358 130.374 157.895 1.00 37.00  ? 86  ARG E C   1 
ATOM   11445 O O   . ARG E 2 84  ? 142.918 131.145 157.112 1.00 37.00  ? 86  ARG E O   1 
ATOM   11446 C CB  . ARG E 2 84  ? 143.472 128.167 157.541 1.00 37.00  ? 86  ARG E CB  1 
ATOM   11447 C CG  . ARG E 2 84  ? 143.333 126.669 157.401 1.00 37.00  ? 86  ARG E CG  1 
ATOM   11448 C CD  . ARG E 2 84  ? 144.679 125.988 157.508 1.00 37.00  ? 86  ARG E CD  1 
ATOM   11449 N NE  . ARG E 2 84  ? 145.084 125.374 156.250 1.00 37.00  ? 86  ARG E NE  1 
ATOM   11450 C CZ  . ARG E 2 84  ? 146.344 125.190 155.883 1.00 37.00  ? 86  ARG E CZ  1 
ATOM   11451 N NH1 . ARG E 2 84  ? 147.349 125.588 156.645 1.00 37.00  ? 86  ARG E NH1 1 
ATOM   11452 N NH2 . ARG E 2 84  ? 146.602 124.594 154.724 1.00 37.00  ? 86  ARG E NH2 1 
ATOM   11453 N N   . GLN E 2 85  ? 141.920 130.743 159.095 1.00 31.03  ? 87  GLN E N   1 
ATOM   11454 C CA  . GLN E 2 85  ? 142.074 132.103 159.587 1.00 31.03  ? 87  GLN E CA  1 
ATOM   11455 C C   . GLN E 2 85  ? 142.424 132.070 161.064 1.00 31.03  ? 87  GLN E C   1 
ATOM   11456 O O   . GLN E 2 85  ? 141.888 131.253 161.815 1.00 31.03  ? 87  GLN E O   1 
ATOM   11457 C CB  . GLN E 2 85  ? 140.797 132.921 159.373 1.00 31.03  ? 87  GLN E CB  1 
ATOM   11458 C CG  . GLN E 2 85  ? 139.520 132.128 159.546 1.00 31.03  ? 87  GLN E CG  1 
ATOM   11459 C CD  . GLN E 2 85  ? 138.311 132.844 158.985 1.00 31.03  ? 87  GLN E CD  1 
ATOM   11460 O OE1 . GLN E 2 85  ? 138.424 133.935 158.432 1.00 31.03  ? 87  GLN E OE1 1 
ATOM   11461 N NE2 . GLN E 2 85  ? 137.143 132.232 159.126 1.00 31.03  ? 87  GLN E NE2 1 
ATOM   11462 N N   . LYS E 2 86  ? 143.327 132.955 161.476 1.00 31.15  ? 88  LYS E N   1 
ATOM   11463 C CA  . LYS E 2 86  ? 143.680 133.089 162.880 1.00 31.15  ? 88  LYS E CA  1 
ATOM   11464 C C   . LYS E 2 86  ? 143.758 134.565 163.238 1.00 31.15  ? 88  LYS E C   1 
ATOM   11465 O O   . LYS E 2 86  ? 144.046 135.411 162.389 1.00 31.15  ? 88  LYS E O   1 
ATOM   11466 C CB  . LYS E 2 86  ? 145.005 132.387 163.204 1.00 31.15  ? 88  LYS E CB  1 
ATOM   11467 C CG  . LYS E 2 86  ? 146.241 133.230 162.975 1.00 31.15  ? 88  LYS E CG  1 
ATOM   11468 C CD  . LYS E 2 86  ? 147.506 132.428 163.233 1.00 31.15  ? 88  LYS E CD  1 
ATOM   11469 C CE  . LYS E 2 86  ? 147.808 132.332 164.719 1.00 31.15  ? 88  LYS E CE  1 
ATOM   11470 N NZ  . LYS E 2 86  ? 148.418 133.582 165.247 1.00 31.15  ? 88  LYS E NZ  1 
ATOM   11471 N N   . TRP E 2 87  ? 143.486 134.866 164.503 1.00 31.10  ? 89  TRP E N   1 
ATOM   11472 C CA  . TRP E 2 87  ? 143.488 136.240 164.988 1.00 31.10  ? 89  TRP E CA  1 
ATOM   11473 C C   . TRP E 2 87  ? 143.902 136.232 166.454 1.00 31.10  ? 89  TRP E C   1 
ATOM   11474 O O   . TRP E 2 87  ? 144.342 135.209 166.987 1.00 31.10  ? 89  TRP E O   1 
ATOM   11475 C CB  . TRP E 2 87  ? 142.115 136.888 164.776 1.00 31.10  ? 89  TRP E CB  1 
ATOM   11476 C CG  . TRP E 2 87  ? 141.003 136.180 165.471 1.00 31.10  ? 89  TRP E CG  1 
ATOM   11477 C CD1 . TRP E 2 87  ? 140.493 136.470 166.698 1.00 31.10  ? 89  TRP E CD1 1 
ATOM   11478 C CD2 . TRP E 2 87  ? 140.254 135.065 164.978 1.00 31.10  ? 89  TRP E CD2 1 
ATOM   11479 N NE1 . TRP E 2 87  ? 139.474 135.603 167.004 1.00 31.10  ? 89  TRP E NE1 1 
ATOM   11480 C CE2 . TRP E 2 87  ? 139.308 134.730 165.963 1.00 31.10  ? 89  TRP E CE2 1 
ATOM   11481 C CE3 . TRP E 2 87  ? 140.293 134.316 163.801 1.00 31.10  ? 89  TRP E CE3 1 
ATOM   11482 C CZ2 . TRP E 2 87  ? 138.410 133.680 165.808 1.00 31.10  ? 89  TRP E CZ2 1 
ATOM   11483 C CZ3 . TRP E 2 87  ? 139.400 133.275 163.649 1.00 31.10  ? 89  TRP E CZ3 1 
ATOM   11484 C CH2 . TRP E 2 87  ? 138.472 132.966 164.647 1.00 31.10  ? 89  TRP E CH2 1 
ATOM   11485 N N   . ASN E 2 88  ? 143.765 137.379 167.110 1.00 40.03  ? 90  ASN E N   1 
ATOM   11486 C CA  . ASN E 2 88  ? 144.140 137.534 168.508 1.00 40.03  ? 90  ASN E CA  1 
ATOM   11487 C C   . ASN E 2 88  ? 142.894 137.783 169.344 1.00 40.03  ? 90  ASN E C   1 
ATOM   11488 O O   . ASN E 2 88  ? 142.126 138.707 169.059 1.00 40.03  ? 90  ASN E O   1 
ATOM   11489 C CB  . ASN E 2 88  ? 145.133 138.684 168.683 1.00 40.03  ? 90  ASN E CB  1 
ATOM   11490 C CG  . ASN E 2 88  ? 146.465 138.222 169.235 1.00 40.03  ? 90  ASN E CG  1 
ATOM   11491 O OD1 . ASN E 2 88  ? 146.924 137.121 168.937 1.00 40.03  ? 90  ASN E OD1 1 
ATOM   11492 N ND2 . ASN E 2 88  ? 147.095 139.063 170.046 1.00 40.03  ? 90  ASN E ND2 1 
ATOM   11493 N N   . ASP E 2 89  ? 142.698 136.961 170.372 1.00 47.54  ? 91  ASP E N   1 
ATOM   11494 C CA  . ASP E 2 89  ? 141.544 137.067 171.264 1.00 47.54  ? 91  ASP E CA  1 
ATOM   11495 C C   . ASP E 2 89  ? 142.054 137.131 172.696 1.00 47.54  ? 91  ASP E C   1 
ATOM   11496 O O   . ASP E 2 89  ? 142.299 136.094 173.327 1.00 47.54  ? 91  ASP E O   1 
ATOM   11497 C CB  . ASP E 2 89  ? 140.586 135.896 171.064 1.00 47.54  ? 91  ASP E CB  1 
ATOM   11498 C CG  . ASP E 2 89  ? 139.140 136.278 171.300 1.00 47.54  ? 91  ASP E CG  1 
ATOM   11499 O OD1 . ASP E 2 89  ? 138.809 137.472 171.154 1.00 47.54  ? 91  ASP E OD1 1 
ATOM   11500 O OD2 . ASP E 2 89  ? 138.333 135.385 171.629 1.00 47.54  ? 91  ASP E OD2 1 
ATOM   11501 N N   . PRO E 2 90  ? 142.237 138.337 173.241 1.00 48.84  ? 92  PRO E N   1 
ATOM   11502 C CA  . PRO E 2 90  ? 142.794 138.446 174.601 1.00 48.84  ? 92  PRO E CA  1 
ATOM   11503 C C   . PRO E 2 90  ? 141.965 137.749 175.666 1.00 48.84  ? 92  PRO E C   1 
ATOM   11504 O O   . PRO E 2 90  ? 142.533 137.150 176.587 1.00 48.84  ? 92  PRO E O   1 
ATOM   11505 C CB  . PRO E 2 90  ? 142.855 139.962 174.828 1.00 48.84  ? 92  PRO E CB  1 
ATOM   11506 C CG  . PRO E 2 90  ? 141.841 140.526 173.893 1.00 48.84  ? 92  PRO E CG  1 
ATOM   11507 C CD  . PRO E 2 90  ? 141.889 139.651 172.680 1.00 48.84  ? 92  PRO E CD  1 
ATOM   11508 N N   . ARG E 2 91  ? 140.636 137.803 175.570 1.00 49.01  ? 93  ARG E N   1 
ATOM   11509 C CA  . ARG E 2 91  ? 139.796 137.140 176.559 1.00 49.01  ? 93  ARG E CA  1 
ATOM   11510 C C   . ARG E 2 91  ? 139.779 135.628 176.396 1.00 49.01  ? 93  ARG E C   1 
ATOM   11511 O O   . ARG E 2 91  ? 139.252 134.933 177.270 1.00 49.01  ? 93  ARG E O   1 
ATOM   11512 C CB  . ARG E 2 91  ? 138.365 137.678 176.497 1.00 49.01  ? 93  ARG E CB  1 
ATOM   11513 C CG  . ARG E 2 91  ? 138.018 138.392 175.208 1.00 49.01  ? 93  ARG E CG  1 
ATOM   11514 C CD  . ARG E 2 91  ? 136.534 138.705 175.147 1.00 49.01  ? 93  ARG E CD  1 
ATOM   11515 N NE  . ARG E 2 91  ? 136.154 139.310 173.878 1.00 49.01  ? 93  ARG E NE  1 
ATOM   11516 C CZ  . ARG E 2 91  ? 135.992 138.639 172.746 1.00 49.01  ? 93  ARG E CZ  1 
ATOM   11517 N NH1 . ARG E 2 91  ? 136.167 137.330 172.686 1.00 49.01  ? 93  ARG E NH1 1 
ATOM   11518 N NH2 . ARG E 2 91  ? 135.646 139.300 171.645 1.00 49.01  ? 93  ARG E NH2 1 
ATOM   11519 N N   . LEU E 2 92  ? 140.333 135.109 175.305 1.00 49.78  ? 94  LEU E N   1 
ATOM   11520 C CA  . LEU E 2 92  ? 140.436 133.678 175.070 1.00 49.78  ? 94  LEU E CA  1 
ATOM   11521 C C   . LEU E 2 92  ? 141.758 133.102 175.547 1.00 49.78  ? 94  LEU E C   1 
ATOM   11522 O O   . LEU E 2 92  ? 142.046 131.934 175.267 1.00 49.78  ? 94  LEU E O   1 
ATOM   11523 C CB  . LEU E 2 92  ? 140.258 133.379 173.584 1.00 49.78  ? 94  LEU E CB  1 
ATOM   11524 C CG  . LEU E 2 92  ? 139.052 132.541 173.179 1.00 49.78  ? 94  LEU E CG  1 
ATOM   11525 C CD1 . LEU E 2 92  ? 139.233 132.058 171.754 1.00 49.78  ? 94  LEU E CD1 1 
ATOM   11526 C CD2 . LEU E 2 92  ? 138.887 131.375 174.130 1.00 49.78  ? 94  LEU E CD2 1 
ATOM   11527 N N   . LYS E 2 93  ? 142.569 133.897 176.242 1.00 57.92  ? 95  LYS E N   1 
ATOM   11528 C CA  . LYS E 2 93  ? 143.888 133.449 176.664 1.00 57.92  ? 95  LYS E CA  1 
ATOM   11529 C C   . LYS E 2 93  ? 143.777 132.219 177.552 1.00 57.92  ? 95  LYS E C   1 
ATOM   11530 O O   . LYS E 2 93  ? 142.966 132.179 178.481 1.00 57.92  ? 95  LYS E O   1 
ATOM   11531 C CB  . LYS E 2 93  ? 144.611 134.578 177.400 1.00 57.92  ? 95  LYS E CB  1 
ATOM   11532 C CG  . LYS E 2 93  ? 145.671 134.111 178.382 1.00 57.92  ? 95  LYS E CG  1 
ATOM   11533 C CD  . LYS E 2 93  ? 146.137 135.249 179.278 1.00 57.92  ? 95  LYS E CD  1 
ATOM   11534 C CE  . LYS E 2 93  ? 147.276 136.025 178.636 1.00 57.92  ? 95  LYS E CE  1 
ATOM   11535 N NZ  . LYS E 2 93  ? 148.092 136.760 179.642 1.00 57.92  ? 95  LYS E NZ  1 
ATOM   11536 N N   . LEU E 2 94  ? 144.593 131.216 177.257 1.00 69.65  ? 96  LEU E N   1 
ATOM   11537 C CA  . LEU E 2 94  ? 144.548 129.969 178.008 1.00 69.65  ? 96  LEU E CA  1 
ATOM   11538 C C   . LEU E 2 94  ? 144.949 130.223 179.455 1.00 69.65  ? 96  LEU E C   1 
ATOM   11539 O O   . LEU E 2 94  ? 145.970 130.873 179.705 1.00 69.65  ? 96  LEU E O   1 
ATOM   11540 C CB  . LEU E 2 94  ? 145.477 128.936 177.379 1.00 69.65  ? 96  LEU E CB  1 
ATOM   11541 C CG  . LEU E 2 94  ? 144.816 127.877 176.498 1.00 69.65  ? 96  LEU E CG  1 
ATOM   11542 C CD1 . LEU E 2 94  ? 145.824 126.813 176.099 1.00 69.65  ? 96  LEU E CD1 1 
ATOM   11543 C CD2 . LEU E 2 94  ? 143.628 127.257 177.210 1.00 69.65  ? 96  LEU E CD2 1 
ATOM   11544 N N   . PRO E 2 95  ? 144.175 129.746 180.428 1.00 84.44  ? 97  PRO E N   1 
ATOM   11545 C CA  . PRO E 2 95  ? 144.557 129.939 181.829 1.00 84.44  ? 97  PRO E CA  1 
ATOM   11546 C C   . PRO E 2 95  ? 145.866 129.231 182.143 1.00 84.44  ? 97  PRO E C   1 
ATOM   11547 O O   . PRO E 2 95  ? 146.213 128.217 181.534 1.00 84.44  ? 97  PRO E O   1 
ATOM   11548 C CB  . PRO E 2 95  ? 143.386 129.327 182.607 1.00 84.44  ? 97  PRO E CB  1 
ATOM   11549 C CG  . PRO E 2 95  ? 142.245 129.318 181.643 1.00 84.44  ? 97  PRO E CG  1 
ATOM   11550 C CD  . PRO E 2 95  ? 142.860 129.099 180.295 1.00 84.44  ? 97  PRO E CD  1 
ATOM   11551 N N   . SER E 2 96  ? 146.598 129.787 183.109 1.00 93.31  ? 98  SER E N   1 
ATOM   11552 C CA  . SER E 2 96  ? 147.901 129.249 183.477 1.00 93.31  ? 98  SER E CA  1 
ATOM   11553 C C   . SER E 2 96  ? 147.822 127.849 184.070 1.00 93.31  ? 98  SER E C   1 
ATOM   11554 O O   . SER E 2 96  ? 148.859 127.185 184.175 1.00 93.31  ? 98  SER E O   1 
ATOM   11555 C CB  . SER E 2 96  ? 148.592 130.187 184.466 1.00 93.31  ? 98  SER E CB  1 
ATOM   11556 O OG  . SER E 2 96  ? 147.858 130.282 185.674 1.00 93.31  ? 98  SER E OG  1 
ATOM   11557 N N   . ASP E 2 97  ? 146.632 127.391 184.467 1.00 91.83  ? 99  ASP E N   1 
ATOM   11558 C CA  . ASP E 2 97  ? 146.505 126.045 185.017 1.00 91.83  ? 99  ASP E CA  1 
ATOM   11559 C C   . ASP E 2 97  ? 146.866 124.988 183.980 1.00 91.83  ? 99  ASP E C   1 
ATOM   11560 O O   . ASP E 2 97  ? 147.537 123.998 184.298 1.00 91.83  ? 99  ASP E O   1 
ATOM   11561 C CB  . ASP E 2 97  ? 145.087 125.822 185.545 1.00 91.83  ? 99  ASP E CB  1 
ATOM   11562 C CG  . ASP E 2 97  ? 144.031 125.935 184.461 1.00 91.83  ? 99  ASP E CG  1 
ATOM   11563 O OD1 . ASP E 2 97  ? 144.361 126.385 183.344 1.00 91.83  ? 99  ASP E OD1 1 
ATOM   11564 O OD2 . ASP E 2 97  ? 142.866 125.570 184.726 1.00 91.83  ? 99  ASP E OD2 1 
ATOM   11565 N N   . PHE E 2 98  ? 146.431 125.178 182.738 1.00 85.87  ? 100 PHE E N   1 
ATOM   11566 C CA  . PHE E 2 98  ? 146.726 124.225 181.681 1.00 85.87  ? 100 PHE E CA  1 
ATOM   11567 C C   . PHE E 2 98  ? 148.150 124.411 181.177 1.00 85.87  ? 100 PHE E C   1 
ATOM   11568 O O   . PHE E 2 98  ? 148.619 125.538 180.994 1.00 85.87  ? 100 PHE E O   1 
ATOM   11569 C CB  . PHE E 2 98  ? 145.738 124.383 180.526 1.00 85.87  ? 100 PHE E CB  1 
ATOM   11570 C CG  . PHE E 2 98  ? 146.064 123.535 179.333 1.00 85.87  ? 100 PHE E CG  1 
ATOM   11571 C CD1 . PHE E 2 98  ? 145.729 122.193 179.312 1.00 85.87  ? 100 PHE E CD1 1 
ATOM   11572 C CD2 . PHE E 2 98  ? 146.705 124.078 178.233 1.00 85.87  ? 100 PHE E CD2 1 
ATOM   11573 C CE1 . PHE E 2 98  ? 146.027 121.409 178.217 1.00 85.87  ? 100 PHE E CE1 1 
ATOM   11574 C CE2 . PHE E 2 98  ? 147.007 123.299 177.136 1.00 85.87  ? 100 PHE E CE2 1 
ATOM   11575 C CZ  . PHE E 2 98  ? 146.667 121.962 177.127 1.00 85.87  ? 100 PHE E CZ  1 
ATOM   11576 N N   . ARG E 2 99  ? 148.834 123.293 180.949 1.00 81.97  ? 101 ARG E N   1 
ATOM   11577 C CA  . ARG E 2 99  ? 150.196 123.318 180.435 1.00 81.97  ? 101 ARG E CA  1 
ATOM   11578 C C   . ARG E 2 99  ? 150.500 121.970 179.803 1.00 81.97  ? 101 ARG E C   1 
ATOM   11579 O O   . ARG E 2 99  ? 149.794 120.984 180.027 1.00 81.97  ? 101 ARG E O   1 
ATOM   11580 C CB  . ARG E 2 99  ? 151.209 123.642 181.538 1.00 81.97  ? 101 ARG E CB  1 
ATOM   11581 N N   . GLY E 2 100 ? 151.569 121.941 179.011 1.00 77.75  ? 102 GLY E N   1 
ATOM   11582 C CA  . GLY E 2 100 ? 152.008 120.733 178.348 1.00 77.75  ? 102 GLY E CA  1 
ATOM   11583 C C   . GLY E 2 100 ? 151.663 120.648 176.878 1.00 77.75  ? 102 GLY E C   1 
ATOM   11584 O O   . GLY E 2 100 ? 152.150 119.735 176.199 1.00 77.75  ? 102 GLY E O   1 
ATOM   11585 N N   . SER E 2 101 ? 150.841 121.560 176.365 1.00 75.85  ? 103 SER E N   1 
ATOM   11586 C CA  . SER E 2 101 ? 150.491 121.573 174.952 1.00 75.85  ? 103 SER E CA  1 
ATOM   11587 C C   . SER E 2 101 ? 150.517 123.004 174.442 1.00 75.85  ? 103 SER E C   1 
ATOM   11588 O O   . SER E 2 101 ? 149.871 123.883 175.020 1.00 75.85  ? 103 SER E O   1 
ATOM   11589 C CB  . SER E 2 101 ? 149.110 120.949 174.716 1.00 75.85  ? 103 SER E CB  1 
ATOM   11590 O OG  . SER E 2 101 ? 149.203 119.542 174.581 1.00 75.85  ? 103 SER E OG  1 
ATOM   11591 N N   . ASP E 2 102 ? 151.266 123.233 173.361 1.00 71.61  ? 104 ASP E N   1 
ATOM   11592 C CA  . ASP E 2 102 ? 151.296 124.558 172.753 1.00 71.61  ? 104 ASP E CA  1 
ATOM   11593 C C   . ASP E 2 102 ? 149.965 124.901 172.097 1.00 71.61  ? 104 ASP E C   1 
ATOM   11594 O O   . ASP E 2 102 ? 149.591 126.077 172.035 1.00 71.61  ? 104 ASP E O   1 
ATOM   11595 C CB  . ASP E 2 102 ? 152.436 124.644 171.737 1.00 71.61  ? 104 ASP E CB  1 
ATOM   11596 C CG  . ASP E 2 102 ? 152.077 124.026 170.398 1.00 71.61  ? 104 ASP E CG  1 
ATOM   11597 O OD1 . ASP E 2 102 ? 151.506 124.737 169.544 1.00 71.61  ? 104 ASP E OD1 1 
ATOM   11598 O OD2 . ASP E 2 102 ? 152.362 122.826 170.200 1.00 71.61  ? 104 ASP E OD2 1 
ATOM   11599 N N   . ALA E 2 103 ? 149.245 123.897 171.603 1.00 59.41  ? 105 ALA E N   1 
ATOM   11600 C CA  . ALA E 2 103 ? 147.946 124.089 170.974 1.00 59.41  ? 105 ALA E CA  1 
ATOM   11601 C C   . ALA E 2 103 ? 146.935 123.174 171.643 1.00 59.41  ? 105 ALA E C   1 
ATOM   11602 O O   . ALA E 2 103 ? 147.189 121.977 171.804 1.00 59.41  ? 105 ALA E O   1 
ATOM   11603 C CB  . ALA E 2 103 ? 148.007 123.800 169.472 1.00 59.41  ? 105 ALA E CB  1 
ATOM   11604 N N   . LEU E 2 104 ? 145.795 123.736 172.030 1.00 47.78  ? 106 LEU E N   1 
ATOM   11605 C CA  . LEU E 2 104 ? 144.720 122.986 172.662 1.00 47.78  ? 106 LEU E CA  1 
ATOM   11606 C C   . LEU E 2 104 ? 143.550 122.892 171.693 1.00 47.78  ? 106 LEU E C   1 
ATOM   11607 O O   . LEU E 2 104 ? 142.971 123.916 171.317 1.00 47.78  ? 106 LEU E O   1 
ATOM   11608 C CB  . LEU E 2 104 ? 144.281 123.649 173.966 1.00 47.78  ? 106 LEU E CB  1 
ATOM   11609 C CG  . LEU E 2 104 ? 142.924 123.195 174.504 1.00 47.78  ? 106 LEU E CG  1 
ATOM   11610 C CD1 . LEU E 2 104 ? 143.032 121.809 175.114 1.00 47.78  ? 106 LEU E CD1 1 
ATOM   11611 C CD2 . LEU E 2 104 ? 142.379 124.188 175.515 1.00 47.78  ? 106 LEU E CD2 1 
ATOM   11612 N N   . THR E 2 105 ? 143.210 121.673 171.290 1.00 44.13  ? 107 THR E N   1 
ATOM   11613 C CA  . THR E 2 105 ? 142.031 121.459 170.466 1.00 44.13  ? 107 THR E CA  1 
ATOM   11614 C C   . THR E 2 105 ? 140.777 121.600 171.316 1.00 44.13  ? 107 THR E C   1 
ATOM   11615 O O   . THR E 2 105 ? 140.768 121.245 172.497 1.00 44.13  ? 107 THR E O   1 
ATOM   11616 C CB  . THR E 2 105 ? 142.069 120.079 169.811 1.00 44.13  ? 107 THR E CB  1 
ATOM   11617 O OG1 . THR E 2 105 ? 143.420 119.746 169.475 1.00 44.13  ? 107 THR E OG1 1 
ATOM   11618 C CG2 . THR E 2 105 ? 141.225 120.070 168.550 1.00 44.13  ? 107 THR E CG2 1 
ATOM   11619 N N   . VAL E 2 106 ? 139.716 122.130 170.714 1.00 45.25  ? 108 VAL E N   1 
ATOM   11620 C CA  . VAL E 2 106 ? 138.454 122.342 171.397 1.00 45.25  ? 108 VAL E CA  1 
ATOM   11621 C C   . VAL E 2 106 ? 137.336 121.722 170.568 1.00 45.25  ? 108 VAL E C   1 
ATOM   11622 O O   . VAL E 2 106 ? 137.571 121.084 169.543 1.00 45.25  ? 108 VAL E O   1 
ATOM   11623 C CB  . VAL E 2 106 ? 138.172 123.833 171.668 1.00 45.25  ? 108 VAL E CB  1 
ATOM   11624 C CG1 . VAL E 2 106 ? 139.266 124.432 172.538 1.00 45.25  ? 108 VAL E CG1 1 
ATOM   11625 C CG2 . VAL E 2 106 ? 138.031 124.587 170.366 1.00 45.25  ? 108 VAL E CG2 1 
ATOM   11626 N N   . ASP E 2 107 ? 136.111 121.920 171.031 1.00 59.61  ? 109 ASP E N   1 
ATOM   11627 C CA  . ASP E 2 107 ? 134.959 121.248 170.452 1.00 59.61  ? 109 ASP E CA  1 
ATOM   11628 C C   . ASP E 2 107 ? 134.485 121.975 169.199 1.00 59.61  ? 109 ASP E C   1 
ATOM   11629 O O   . ASP E 2 107 ? 134.171 123.171 169.269 1.00 59.61  ? 109 ASP E O   1 
ATOM   11630 C CB  . ASP E 2 107 ? 133.835 121.180 171.473 1.00 59.61  ? 109 ASP E CB  1 
ATOM   11631 C CG  . ASP E 2 107 ? 134.341 120.864 172.866 1.00 59.61  ? 109 ASP E CG  1 
ATOM   11632 O OD1 . ASP E 2 107 ? 135.152 119.925 173.004 1.00 59.61  ? 109 ASP E OD1 1 
ATOM   11633 O OD2 . ASP E 2 107 ? 133.933 121.556 173.823 1.00 59.61  ? 109 ASP E OD2 1 
ATOM   11634 N N   . PRO E 2 108 ? 134.414 121.304 168.048 1.00 44.61  ? 110 PRO E N   1 
ATOM   11635 C CA  . PRO E 2 108 ? 133.817 121.942 166.866 1.00 44.61  ? 110 PRO E CA  1 
ATOM   11636 C C   . PRO E 2 108 ? 132.378 122.367 167.081 1.00 44.61  ? 110 PRO E C   1 
ATOM   11637 O O   . PRO E 2 108 ? 131.907 123.277 166.390 1.00 44.61  ? 110 PRO E O   1 
ATOM   11638 C CB  . PRO E 2 108 ? 133.930 120.857 165.789 1.00 44.61  ? 110 PRO E CB  1 
ATOM   11639 C CG  . PRO E 2 108 ? 135.062 120.002 166.238 1.00 44.61  ? 110 PRO E CG  1 
ATOM   11640 C CD  . PRO E 2 108 ? 134.995 119.989 167.735 1.00 44.61  ? 110 PRO E CD  1 
ATOM   11641 N N   . THR E 2 109 ? 131.657 121.731 168.005 1.00 56.91  ? 111 THR E N   1 
ATOM   11642 C CA  . THR E 2 109 ? 130.333 122.222 168.368 1.00 56.91  ? 111 THR E CA  1 
ATOM   11643 C C   . THR E 2 109 ? 130.428 123.572 169.068 1.00 56.91  ? 111 THR E C   1 
ATOM   11644 O O   . THR E 2 109 ? 129.673 124.500 168.755 1.00 56.91  ? 111 THR E O   1 
ATOM   11645 C CB  . THR E 2 109 ? 129.616 121.204 169.255 1.00 56.91  ? 111 THR E CB  1 
ATOM   11646 O OG1 . THR E 2 109 ? 129.462 119.972 168.541 1.00 56.91  ? 111 THR E OG1 1 
ATOM   11647 C CG2 . THR E 2 109 ? 128.243 121.722 169.658 1.00 56.91  ? 111 THR E CG2 1 
ATOM   11648 N N   . MET E 2 110 ? 131.364 123.707 170.011 1.00 59.62  ? 112 MET E N   1 
ATOM   11649 C CA  . MET E 2 110 ? 131.565 124.984 170.686 1.00 59.62  ? 112 MET E CA  1 
ATOM   11650 C C   . MET E 2 110 ? 132.231 126.019 169.796 1.00 59.62  ? 112 MET E C   1 
ATOM   11651 O O   . MET E 2 110 ? 132.339 127.180 170.204 1.00 59.62  ? 112 MET E O   1 
ATOM   11652 C CB  . MET E 2 110 ? 132.394 124.797 171.956 1.00 59.62  ? 112 MET E CB  1 
ATOM   11653 C CG  . MET E 2 110 ? 131.809 123.799 172.930 1.00 59.62  ? 112 MET E CG  1 
ATOM   11654 S SD  . MET E 2 110 ? 131.880 124.372 174.638 1.00 59.62  ? 112 MET E SD  1 
ATOM   11655 C CE  . MET E 2 110 ? 130.685 125.706 174.596 1.00 59.62  ? 112 MET E CE  1 
ATOM   11656 N N   . TYR E 2 111 ? 132.691 125.624 168.608 1.00 56.59  ? 113 TYR E N   1 
ATOM   11657 C CA  . TYR E 2 111 ? 133.260 126.594 167.678 1.00 56.59  ? 113 TYR E CA  1 
ATOM   11658 C C   . TYR E 2 111 ? 132.278 127.716 167.367 1.00 56.59  ? 113 TYR E C   1 
ATOM   11659 O O   . TYR E 2 111 ? 132.693 128.841 167.069 1.00 56.59  ? 113 TYR E O   1 
ATOM   11660 C CB  . TYR E 2 111 ? 133.691 125.891 166.392 1.00 56.59  ? 113 TYR E CB  1 
ATOM   11661 C CG  . TYR E 2 111 ? 133.539 126.721 165.141 1.00 56.59  ? 113 TYR E CG  1 
ATOM   11662 C CD1 . TYR E 2 111 ? 134.520 127.629 164.771 1.00 56.59  ? 113 TYR E CD1 1 
ATOM   11663 C CD2 . TYR E 2 111 ? 132.429 126.582 164.317 1.00 56.59  ? 113 TYR E CD2 1 
ATOM   11664 C CE1 . TYR E 2 111 ? 134.396 128.387 163.628 1.00 56.59  ? 113 TYR E CE1 1 
ATOM   11665 C CE2 . TYR E 2 111 ? 132.297 127.337 163.169 1.00 56.59  ? 113 TYR E CE2 1 
ATOM   11666 C CZ  . TYR E 2 111 ? 133.288 128.234 162.827 1.00 56.59  ? 113 TYR E CZ  1 
ATOM   11667 O OH  . TYR E 2 111 ? 133.166 128.995 161.689 1.00 56.59  ? 113 TYR E OH  1 
ATOM   11668 N N   . LYS E 2 112 ? 130.976 127.431 167.430 1.00 58.15  ? 114 LYS E N   1 
ATOM   11669 C CA  . LYS E 2 112 ? 129.975 128.469 167.217 1.00 58.15  ? 114 LYS E CA  1 
ATOM   11670 C C   . LYS E 2 112 ? 129.932 129.460 168.374 1.00 58.15  ? 114 LYS E C   1 
ATOM   11671 O O   . LYS E 2 112 ? 129.496 130.602 168.194 1.00 58.15  ? 114 LYS E O   1 
ATOM   11672 C CB  . LYS E 2 112 ? 128.602 127.826 167.018 1.00 58.15  ? 114 LYS E CB  1 
ATOM   11673 C CG  . LYS E 2 112 ? 127.492 128.799 166.661 1.00 58.15  ? 114 LYS E CG  1 
ATOM   11674 C CD  . LYS E 2 112 ? 126.184 128.425 167.345 1.00 58.15  ? 114 LYS E CD  1 
ATOM   11675 C CE  . LYS E 2 112 ? 126.037 129.115 168.697 1.00 58.15  ? 114 LYS E CE  1 
ATOM   11676 N NZ  . LYS E 2 112 ? 127.097 128.742 169.676 1.00 58.15  ? 114 LYS E NZ  1 
ATOM   11677 N N   . CYS E 2 113 ? 130.384 129.051 169.561 1.00 59.49  ? 115 CYS E N   1 
ATOM   11678 C CA  . CYS E 2 113 ? 130.246 129.906 170.736 1.00 59.49  ? 115 CYS E CA  1 
ATOM   11679 C C   . CYS E 2 113 ? 131.213 131.084 170.695 1.00 59.49  ? 115 CYS E C   1 
ATOM   11680 O O   . CYS E 2 113 ? 130.871 132.186 171.138 1.00 59.49  ? 115 CYS E O   1 
ATOM   11681 C CB  . CYS E 2 113 ? 130.458 129.085 172.006 1.00 59.49  ? 115 CYS E CB  1 
ATOM   11682 S SG  . CYS E 2 113 ? 130.282 130.027 173.536 1.00 59.49  ? 115 CYS E SG  1 
ATOM   11683 N N   . LEU E 2 114 ? 132.418 130.878 170.174 1.00 52.39  ? 116 LEU E N   1 
ATOM   11684 C CA  . LEU E 2 114 ? 133.428 131.925 170.200 1.00 52.39  ? 116 LEU E CA  1 
ATOM   11685 C C   . LEU E 2 114 ? 133.118 133.012 169.176 1.00 52.39  ? 116 LEU E C   1 
ATOM   11686 O O   . LEU E 2 114 ? 132.300 132.838 168.270 1.00 52.39  ? 116 LEU E O   1 
ATOM   11687 C CB  . LEU E 2 114 ? 134.812 131.340 169.930 1.00 52.39  ? 116 LEU E CB  1 
ATOM   11688 C CG  . LEU E 2 114 ? 135.252 130.260 170.916 1.00 52.39  ? 116 LEU E CG  1 
ATOM   11689 C CD1 . LEU E 2 114 ? 136.240 129.309 170.270 1.00 52.39  ? 116 LEU E CD1 1 
ATOM   11690 C CD2 . LEU E 2 114 ? 135.841 130.887 172.163 1.00 52.39  ? 116 LEU E CD2 1 
ATOM   11691 N N   . TRP E 2 115 ? 133.786 134.152 169.334 1.00 43.77  ? 117 TRP E N   1 
ATOM   11692 C CA  . TRP E 2 115 ? 133.654 135.228 168.365 1.00 43.77  ? 117 TRP E CA  1 
ATOM   11693 C C   . TRP E 2 115 ? 134.268 134.817 167.034 1.00 43.77  ? 117 TRP E C   1 
ATOM   11694 O O   . TRP E 2 115 ? 135.263 134.091 166.980 1.00 43.77  ? 117 TRP E O   1 
ATOM   11695 C CB  . TRP E 2 115 ? 134.324 136.502 168.872 1.00 43.77  ? 117 TRP E CB  1 
ATOM   11696 C CG  . TRP E 2 115 ? 134.172 137.660 167.934 1.00 43.77  ? 117 TRP E CG  1 
ATOM   11697 C CD1 . TRP E 2 115 ? 133.127 138.531 167.875 1.00 43.77  ? 117 TRP E CD1 1 
ATOM   11698 C CD2 . TRP E 2 115 ? 135.093 138.070 166.918 1.00 43.77  ? 117 TRP E CD2 1 
ATOM   11699 N NE1 . TRP E 2 115 ? 133.339 139.460 166.888 1.00 43.77  ? 117 TRP E NE1 1 
ATOM   11700 C CE2 . TRP E 2 115 ? 134.541 139.199 166.286 1.00 43.77  ? 117 TRP E CE2 1 
ATOM   11701 C CE3 . TRP E 2 115 ? 136.333 137.595 166.485 1.00 43.77  ? 117 TRP E CE3 1 
ATOM   11702 C CZ2 . TRP E 2 115 ? 135.182 139.858 165.243 1.00 43.77  ? 117 TRP E CZ2 1 
ATOM   11703 C CZ3 . TRP E 2 115 ? 136.968 138.252 165.449 1.00 43.77  ? 117 TRP E CZ3 1 
ATOM   11704 C CH2 . TRP E 2 115 ? 136.392 139.370 164.840 1.00 43.77  ? 117 TRP E CH2 1 
ATOM   11705 N N   . LYS E 2 116 ? 133.661 135.292 165.951 1.00 42.23  ? 118 LYS E N   1 
ATOM   11706 C CA  . LYS E 2 116 ? 134.076 134.905 164.616 1.00 42.23  ? 118 LYS E CA  1 
ATOM   11707 C C   . LYS E 2 116 ? 134.298 136.141 163.758 1.00 42.23  ? 118 LYS E C   1 
ATOM   11708 O O   . LYS E 2 116 ? 133.579 137.136 163.903 1.00 42.23  ? 118 LYS E O   1 
ATOM   11709 C CB  . LYS E 2 116 ? 133.015 134.016 163.958 1.00 42.23  ? 118 LYS E CB  1 
ATOM   11710 C CG  . LYS E 2 116 ? 132.342 133.057 164.913 1.00 42.23  ? 118 LYS E CG  1 
ATOM   11711 C CD  . LYS E 2 116 ? 131.227 132.299 164.229 1.00 42.23  ? 118 LYS E CD  1 
ATOM   11712 C CE  . LYS E 2 116 ? 131.692 130.927 163.808 1.00 42.23  ? 118 LYS E CE  1 
ATOM   11713 N NZ  . LYS E 2 116 ? 131.939 130.038 164.979 1.00 42.23  ? 118 LYS E NZ  1 
ATOM   11714 N N   . PRO E 2 117 ? 135.289 136.116 162.866 1.00 34.82  ? 119 PRO E N   1 
ATOM   11715 C CA  . PRO E 2 117 ? 135.425 137.189 161.874 1.00 34.82  ? 119 PRO E CA  1 
ATOM   11716 C C   . PRO E 2 117 ? 134.493 136.919 160.703 1.00 34.82  ? 119 PRO E C   1 
ATOM   11717 O O   . PRO E 2 117 ? 134.621 135.902 160.019 1.00 34.82  ? 119 PRO E O   1 
ATOM   11718 C CB  . PRO E 2 117 ? 136.899 137.100 161.454 1.00 34.82  ? 119 PRO E CB  1 
ATOM   11719 C CG  . PRO E 2 117 ? 137.541 136.147 162.428 1.00 34.82  ? 119 PRO E CG  1 
ATOM   11720 C CD  . PRO E 2 117 ? 136.455 135.225 162.857 1.00 34.82  ? 119 PRO E CD  1 
ATOM   11721 N N   . ASP E 2 118 ? 133.544 137.823 160.484 1.00 34.29  ? 120 ASP E N   1 
ATOM   11722 C CA  . ASP E 2 118 ? 132.625 137.679 159.366 1.00 34.29  ? 120 ASP E CA  1 
ATOM   11723 C C   . ASP E 2 118 ? 133.399 137.731 158.057 1.00 34.29  ? 120 ASP E C   1 
ATOM   11724 O O   . ASP E 2 118 ? 134.241 138.609 157.857 1.00 34.29  ? 120 ASP E O   1 
ATOM   11725 C CB  . ASP E 2 118 ? 131.566 138.777 159.406 1.00 34.29  ? 120 ASP E CB  1 
ATOM   11726 C CG  . ASP E 2 118 ? 130.839 138.935 158.088 1.00 34.29  ? 120 ASP E CG  1 
ATOM   11727 O OD1 . ASP E 2 118 ? 130.531 137.907 157.448 1.00 34.29  ? 120 ASP E OD1 1 
ATOM   11728 O OD2 . ASP E 2 118 ? 130.572 140.087 157.691 1.00 34.29  ? 120 ASP E OD2 1 
ATOM   11729 N N   . LEU E 2 119 ? 133.114 136.788 157.165 1.00 30.58  ? 121 LEU E N   1 
ATOM   11730 C CA  . LEU E 2 119 ? 133.844 136.667 155.914 1.00 30.58  ? 121 LEU E CA  1 
ATOM   11731 C C   . LEU E 2 119 ? 132.902 136.166 154.833 1.00 30.58  ? 121 LEU E C   1 
ATOM   11732 O O   . LEU E 2 119 ? 132.037 135.327 155.096 1.00 30.58  ? 121 LEU E O   1 
ATOM   11733 C CB  . LEU E 2 119 ? 135.035 135.715 156.065 1.00 30.58  ? 121 LEU E CB  1 
ATOM   11734 C CG  . LEU E 2 119 ? 135.978 135.535 154.879 1.00 30.58  ? 121 LEU E CG  1 
ATOM   11735 C CD1 . LEU E 2 119 ? 137.405 135.424 155.373 1.00 30.58  ? 121 LEU E CD1 1 
ATOM   11736 C CD2 . LEU E 2 119 ? 135.602 134.306 154.076 1.00 30.58  ? 121 LEU E CD2 1 
ATOM   11737 N N   . PHE E 2 120 ? 133.073 136.681 153.619 1.00 32.18  ? 122 PHE E N   1 
ATOM   11738 C CA  . PHE E 2 120 ? 132.254 136.257 152.496 1.00 32.18  ? 122 PHE E CA  1 
ATOM   11739 C C   . PHE E 2 120 ? 133.028 136.481 151.209 1.00 32.18  ? 122 PHE E C   1 
ATOM   11740 O O   . PHE E 2 120 ? 133.966 137.278 151.158 1.00 32.18  ? 122 PHE E O   1 
ATOM   11741 C CB  . PHE E 2 120 ? 130.918 137.004 152.456 1.00 32.18  ? 122 PHE E CB  1 
ATOM   11742 C CG  . PHE E 2 120 ? 130.983 138.325 151.751 1.00 32.18  ? 122 PHE E CG  1 
ATOM   11743 C CD1 . PHE E 2 120 ? 131.623 139.402 152.332 1.00 32.18  ? 122 PHE E CD1 1 
ATOM   11744 C CD2 . PHE E 2 120 ? 130.400 138.493 150.510 1.00 32.18  ? 122 PHE E CD2 1 
ATOM   11745 C CE1 . PHE E 2 120 ? 131.684 140.618 151.688 1.00 32.18  ? 122 PHE E CE1 1 
ATOM   11746 C CE2 . PHE E 2 120 ? 130.458 139.709 149.861 1.00 32.18  ? 122 PHE E CE2 1 
ATOM   11747 C CZ  . PHE E 2 120 ? 131.101 140.772 150.452 1.00 32.18  ? 122 PHE E CZ  1 
ATOM   11748 N N   . PHE E 2 121 ? 132.619 135.771 150.165 1.00 30.01  ? 123 PHE E N   1 
ATOM   11749 C CA  . PHE E 2 121 ? 133.279 135.835 148.868 1.00 30.01  ? 123 PHE E CA  1 
ATOM   11750 C C   . PHE E 2 121 ? 132.475 136.741 147.946 1.00 30.01  ? 123 PHE E C   1 
ATOM   11751 O O   . PHE E 2 121 ? 131.288 136.495 147.710 1.00 30.01  ? 123 PHE E O   1 
ATOM   11752 C CB  . PHE E 2 121 ? 133.425 134.438 148.271 1.00 30.01  ? 123 PHE E CB  1 
ATOM   11753 C CG  . PHE E 2 121 ? 134.306 133.532 149.074 1.00 30.01  ? 123 PHE E CG  1 
ATOM   11754 C CD1 . PHE E 2 121 ? 133.794 132.806 150.128 1.00 30.01  ? 123 PHE E CD1 1 
ATOM   11755 C CD2 . PHE E 2 121 ? 135.649 133.413 148.778 1.00 30.01  ? 123 PHE E CD2 1 
ATOM   11756 C CE1 . PHE E 2 121 ? 134.603 131.976 150.869 1.00 30.01  ? 123 PHE E CE1 1 
ATOM   11757 C CE2 . PHE E 2 121 ? 136.463 132.585 149.516 1.00 30.01  ? 123 PHE E CE2 1 
ATOM   11758 C CZ  . PHE E 2 121 ? 135.939 131.866 150.563 1.00 30.01  ? 123 PHE E CZ  1 
ATOM   11759 N N   . ALA E 2 122 ? 133.122 137.786 147.430 1.00 30.64  ? 124 ALA E N   1 
ATOM   11760 C CA  . ALA E 2 122 ? 132.414 138.765 146.612 1.00 30.64  ? 124 ALA E CA  1 
ATOM   11761 C C   . ALA E 2 122 ? 131.929 138.148 145.308 1.00 30.64  ? 124 ALA E C   1 
ATOM   11762 O O   . ALA E 2 122 ? 130.762 138.305 144.933 1.00 30.64  ? 124 ALA E O   1 
ATOM   11763 C CB  . ALA E 2 122 ? 133.314 139.968 146.339 1.00 30.64  ? 124 ALA E CB  1 
ATOM   11764 N N   . ASN E 2 123 ? 132.808 137.440 144.600 1.00 33.65  ? 125 ASN E N   1 
ATOM   11765 C CA  . ASN E 2 123 ? 132.435 136.780 143.350 1.00 33.65  ? 125 ASN E CA  1 
ATOM   11766 C C   . ASN E 2 123 ? 132.072 135.334 143.665 1.00 33.65  ? 125 ASN E C   1 
ATOM   11767 O O   . ASN E 2 123 ? 132.843 134.397 143.452 1.00 33.65  ? 125 ASN E O   1 
ATOM   11768 C CB  . ASN E 2 123 ? 133.559 136.879 142.329 1.00 33.65  ? 125 ASN E CB  1 
ATOM   11769 C CG  . ASN E 2 123 ? 134.895 136.456 142.894 1.00 33.65  ? 125 ASN E CG  1 
ATOM   11770 O OD1 . ASN E 2 123 ? 135.022 136.206 144.091 1.00 33.65  ? 125 ASN E OD1 1 
ATOM   11771 N ND2 . ASN E 2 123 ? 135.900 136.366 142.034 1.00 33.65  ? 125 ASN E ND2 1 
ATOM   11772 N N   . GLU E 2 124 ? 130.863 135.157 144.188 1.00 31.99  ? 126 GLU E N   1 
ATOM   11773 C CA  . GLU E 2 124 ? 130.373 133.852 144.611 1.00 31.99  ? 126 GLU E CA  1 
ATOM   11774 C C   . GLU E 2 124 ? 128.951 133.667 144.114 1.00 31.99  ? 126 GLU E C   1 
ATOM   11775 O O   . GLU E 2 124 ? 128.047 134.396 144.532 1.00 31.99  ? 126 GLU E O   1 
ATOM   11776 C CB  . GLU E 2 124 ? 130.425 133.715 146.133 1.00 31.99  ? 126 GLU E CB  1 
ATOM   11777 C CG  . GLU E 2 124 ? 129.958 132.371 146.643 1.00 31.99  ? 126 GLU E CG  1 
ATOM   11778 C CD  . GLU E 2 124 ? 129.168 132.487 147.928 1.00 31.99  ? 126 GLU E CD  1 
ATOM   11779 O OE1 . GLU E 2 124 ? 129.222 133.559 148.565 1.00 31.99  ? 126 GLU E OE1 1 
ATOM   11780 O OE2 . GLU E 2 124 ? 128.480 131.514 148.295 1.00 31.99  ? 126 GLU E OE2 1 
ATOM   11781 N N   . LYS E 2 125 ? 128.752 132.695 143.226 1.00 32.14  ? 127 LYS E N   1 
ATOM   11782 C CA  . LYS E 2 125 ? 127.398 132.352 142.810 1.00 32.14  ? 127 LYS E CA  1 
ATOM   11783 C C   . LYS E 2 125 ? 126.656 131.632 143.929 1.00 32.14  ? 127 LYS E C   1 
ATOM   11784 O O   . LYS E 2 125 ? 125.496 131.945 144.219 1.00 32.14  ? 127 LYS E O   1 
ATOM   11785 C CB  . LYS E 2 125 ? 127.438 131.495 141.544 1.00 32.14  ? 127 LYS E CB  1 
ATOM   11786 C CG  . LYS E 2 125 ? 128.363 132.027 140.461 1.00 32.14  ? 127 LYS E CG  1 
ATOM   11787 C CD  . LYS E 2 125 ? 127.703 133.137 139.663 1.00 32.14  ? 127 LYS E CD  1 
ATOM   11788 C CE  . LYS E 2 125 ? 127.215 132.630 138.318 1.00 32.14  ? 127 LYS E CE  1 
ATOM   11789 N NZ  . LYS E 2 125 ? 126.626 133.718 137.489 1.00 32.14  ? 127 LYS E NZ  1 
ATOM   11790 N N   . SER E 2 126 ? 127.317 130.674 144.575 1.00 32.57  ? 128 SER E N   1 
ATOM   11791 C CA  . SER E 2 126 ? 126.745 129.928 145.690 1.00 32.57  ? 128 SER E CA  1 
ATOM   11792 C C   . SER E 2 126 ? 127.853 129.126 146.355 1.00 32.57  ? 128 SER E C   1 
ATOM   11793 O O   . SER E 2 126 ? 128.896 128.859 145.754 1.00 32.57  ? 128 SER E O   1 
ATOM   11794 C CB  . SER E 2 126 ? 125.617 128.999 145.233 1.00 32.57  ? 128 SER E CB  1 
ATOM   11795 O OG  . SER E 2 126 ? 126.100 128.026 144.324 1.00 32.57  ? 128 SER E OG  1 
ATOM   11796 N N   . ALA E 2 127 ? 127.608 128.742 147.606 1.00 30.01  ? 129 ALA E N   1 
ATOM   11797 C CA  . ALA E 2 127 ? 128.518 127.886 148.352 1.00 30.01  ? 129 ALA E CA  1 
ATOM   11798 C C   . ALA E 2 127 ? 127.705 126.935 149.213 1.00 30.01  ? 129 ALA E C   1 
ATOM   11799 O O   . ALA E 2 127 ? 126.533 127.180 149.507 1.00 30.01  ? 129 ALA E O   1 
ATOM   11800 C CB  . ALA E 2 127 ? 129.483 128.690 149.223 1.00 30.01  ? 129 ALA E CB  1 
ATOM   11801 N N   . ASN E 2 128 ? 128.339 125.839 149.619 1.00 32.45  ? 130 ASN E N   1 
ATOM   11802 C CA  . ASN E 2 128 ? 127.625 124.730 150.241 1.00 32.45  ? 130 ASN E CA  1 
ATOM   11803 C C   . ASN E 2 128 ? 128.528 124.193 151.343 1.00 32.45  ? 130 ASN E C   1 
ATOM   11804 O O   . ASN E 2 128 ? 129.559 123.580 151.057 1.00 32.45  ? 130 ASN E O   1 
ATOM   11805 C CB  . ASN E 2 128 ? 127.295 123.668 149.182 1.00 32.45  ? 130 ASN E CB  1 
ATOM   11806 C CG  . ASN E 2 128 ? 127.028 122.276 149.752 1.00 32.45  ? 130 ASN E CG  1 
ATOM   11807 O OD1 . ASN E 2 128 ? 126.982 122.059 150.961 1.00 32.45  ? 130 ASN E OD1 1 
ATOM   11808 N ND2 . ASN E 2 128 ? 126.870 121.310 148.852 1.00 32.45  ? 130 ASN E ND2 1 
ATOM   11809 N N   . PHE E 2 129 ? 128.145 124.421 152.596 1.00 33.77  ? 131 PHE E N   1 
ATOM   11810 C CA  . PHE E 2 129 ? 128.898 123.882 153.721 1.00 33.77  ? 131 PHE E CA  1 
ATOM   11811 C C   . PHE E 2 129 ? 128.884 122.360 153.699 1.00 33.77  ? 131 PHE E C   1 
ATOM   11812 O O   . PHE E 2 129 ? 127.858 121.737 153.422 1.00 33.77  ? 131 PHE E O   1 
ATOM   11813 C CB  . PHE E 2 129 ? 128.304 124.369 155.037 1.00 33.77  ? 131 PHE E CB  1 
ATOM   11814 C CG  . PHE E 2 129 ? 129.065 125.482 155.671 1.00 33.77  ? 131 PHE E CG  1 
ATOM   11815 C CD1 . PHE E 2 129 ? 130.248 125.233 156.335 1.00 33.77  ? 131 PHE E CD1 1 
ATOM   11816 C CD2 . PHE E 2 129 ? 128.587 126.775 155.622 1.00 33.77  ? 131 PHE E CD2 1 
ATOM   11817 C CE1 . PHE E 2 129 ? 130.946 126.255 156.924 1.00 33.77  ? 131 PHE E CE1 1 
ATOM   11818 C CE2 . PHE E 2 129 ? 129.281 127.802 156.212 1.00 33.77  ? 131 PHE E CE2 1 
ATOM   11819 C CZ  . PHE E 2 129 ? 130.464 127.542 156.865 1.00 33.77  ? 131 PHE E CZ  1 
ATOM   11820 N N   . HIS E 2 130 ? 130.019 121.758 154.033 1.00 38.13  ? 132 HIS E N   1 
ATOM   11821 C CA  . HIS E 2 130 ? 130.127 120.307 154.077 1.00 38.13  ? 132 HIS E CA  1 
ATOM   11822 C C   . HIS E 2 130 ? 129.928 119.830 155.509 1.00 38.13  ? 132 HIS E C   1 
ATOM   11823 O O   . HIS E 2 130 ? 130.593 120.315 156.428 1.00 38.13  ? 132 HIS E O   1 
ATOM   11824 C CB  . HIS E 2 130 ? 131.478 119.846 153.538 1.00 38.13  ? 132 HIS E CB  1 
ATOM   11825 C CG  . HIS E 2 130 ? 131.595 119.939 152.050 1.00 38.13  ? 132 HIS E CG  1 
ATOM   11826 N ND1 . HIS E 2 130 ? 132.806 120.061 151.404 1.00 38.13  ? 132 HIS E ND1 1 
ATOM   11827 C CD2 . HIS E 2 130 ? 130.651 119.926 151.081 1.00 38.13  ? 132 HIS E CD2 1 
ATOM   11828 C CE1 . HIS E 2 130 ? 132.603 120.120 150.101 1.00 38.13  ? 132 HIS E CE1 1 
ATOM   11829 N NE2 . HIS E 2 130 ? 131.304 120.041 149.878 1.00 38.13  ? 132 HIS E NE2 1 
ATOM   11830 N N   . ASP E 2 131 ? 129.009 118.883 155.694 1.00 37.95  ? 133 ASP E N   1 
ATOM   11831 C CA  . ASP E 2 131 ? 128.725 118.301 157.009 1.00 37.95  ? 133 ASP E CA  1 
ATOM   11832 C C   . ASP E 2 131 ? 128.369 116.831 156.794 1.00 37.95  ? 133 ASP E C   1 
ATOM   11833 O O   . ASP E 2 131 ? 127.215 116.495 156.515 1.00 37.95  ? 133 ASP E O   1 
ATOM   11834 C CB  . ASP E 2 131 ? 127.610 119.057 157.713 1.00 37.95  ? 133 ASP E CB  1 
ATOM   11835 C CG  . ASP E 2 131 ? 126.545 119.541 156.755 1.00 37.95  ? 133 ASP E CG  1 
ATOM   11836 O OD1 . ASP E 2 131 ? 126.519 119.058 155.604 1.00 37.95  ? 133 ASP E OD1 1 
ATOM   11837 O OD2 . ASP E 2 131 ? 125.737 120.408 157.148 1.00 37.95  ? 133 ASP E OD2 1 
ATOM   11838 N N   . VAL E 2 132 ? 129.365 115.960 156.923 1.00 35.57  ? 134 VAL E N   1 
ATOM   11839 C CA  . VAL E 2 132 ? 129.183 114.524 156.760 1.00 35.57  ? 134 VAL E CA  1 
ATOM   11840 C C   . VAL E 2 132 ? 129.682 113.853 158.030 1.00 35.57  ? 134 VAL E C   1 
ATOM   11841 O O   . VAL E 2 132 ? 130.874 113.930 158.355 1.00 35.57  ? 134 VAL E O   1 
ATOM   11842 C CB  . VAL E 2 132 ? 129.915 113.985 155.527 1.00 35.57  ? 134 VAL E CB  1 
ATOM   11843 C CG1 . VAL E 2 132 ? 129.480 112.562 155.247 1.00 35.57  ? 134 VAL E CG1 1 
ATOM   11844 C CG2 . VAL E 2 132 ? 129.641 114.867 154.328 1.00 35.57  ? 134 VAL E CG2 1 
ATOM   11845 N N   . THR E 2 133 ? 128.763 113.216 158.758 1.00 40.19  ? 135 THR E N   1 
ATOM   11846 C CA  . THR E 2 133 ? 129.015 112.488 160.000 1.00 40.19  ? 135 THR E CA  1 
ATOM   11847 C C   . THR E 2 133 ? 129.427 113.423 161.131 1.00 40.19  ? 135 THR E C   1 
ATOM   11848 O O   . THR E 2 133 ? 129.543 112.991 162.282 1.00 40.19  ? 135 THR E O   1 
ATOM   11849 C CB  . THR E 2 133 ? 130.080 111.404 159.808 1.00 40.19  ? 135 THR E CB  1 
ATOM   11850 O OG1 . THR E 2 133 ? 131.357 112.019 159.609 1.00 40.19  ? 135 THR E OG1 1 
ATOM   11851 C CG2 . THR E 2 133 ? 129.750 110.530 158.609 1.00 40.19  ? 135 THR E CG2 1 
ATOM   11852 N N   . GLN E 2 134 ? 129.629 114.700 160.816 1.00 37.86  ? 136 GLN E N   1 
ATOM   11853 C CA  . GLN E 2 134 ? 129.970 115.742 161.774 1.00 37.86  ? 136 GLN E CA  1 
ATOM   11854 C C   . GLN E 2 134 ? 130.100 117.041 160.994 1.00 37.86  ? 136 GLN E C   1 
ATOM   11855 O O   . GLN E 2 134 ? 130.228 117.031 159.767 1.00 37.86  ? 136 GLN E O   1 
ATOM   11856 C CB  . GLN E 2 134 ? 131.273 115.433 162.525 1.00 37.86  ? 136 GLN E CB  1 
ATOM   11857 C CG  . GLN E 2 134 ? 131.531 116.300 163.747 1.00 37.86  ? 136 GLN E CG  1 
ATOM   11858 C CD  . GLN E 2 134 ? 130.825 115.787 164.986 1.00 37.86  ? 136 GLN E CD  1 
ATOM   11859 O OE1 . GLN E 2 134 ? 129.865 115.024 164.897 1.00 37.86  ? 136 GLN E OE1 1 
ATOM   11860 N NE2 . GLN E 2 134 ? 131.302 116.204 166.153 1.00 37.86  ? 136 GLN E NE2 1 
ATOM   11861 N N   . GLU E 2 135 ? 130.056 118.158 161.714 1.00 38.22  ? 137 GLU E N   1 
ATOM   11862 C CA  . GLU E 2 135 ? 130.390 119.435 161.105 1.00 38.22  ? 137 GLU E CA  1 
ATOM   11863 C C   . GLU E 2 135 ? 131.865 119.452 160.727 1.00 38.22  ? 137 GLU E C   1 
ATOM   11864 O O   . GLU E 2 135 ? 132.715 118.937 161.459 1.00 38.22  ? 137 GLU E O   1 
ATOM   11865 C CB  . GLU E 2 135 ? 130.072 120.584 162.060 1.00 38.22  ? 137 GLU E CB  1 
ATOM   11866 C CG  . GLU E 2 135 ? 128.733 121.262 161.806 1.00 38.22  ? 137 GLU E CG  1 
ATOM   11867 C CD  . GLU E 2 135 ? 128.696 122.059 160.512 1.00 38.22  ? 137 GLU E CD  1 
ATOM   11868 O OE1 . GLU E 2 135 ? 129.740 122.166 159.835 1.00 38.22  ? 137 GLU E OE1 1 
ATOM   11869 O OE2 . GLU E 2 135 ? 127.615 122.583 160.172 1.00 38.22  ? 137 GLU E OE2 1 
ATOM   11870 N N   . ASN E 2 136 ? 132.170 120.039 159.571 1.00 35.83  ? 138 ASN E N   1 
ATOM   11871 C CA  . ASN E 2 136 ? 133.538 120.049 159.054 1.00 35.83  ? 138 ASN E CA  1 
ATOM   11872 C C   . ASN E 2 136 ? 134.230 121.351 159.456 1.00 35.83  ? 138 ASN E C   1 
ATOM   11873 O O   . ASN E 2 136 ? 134.505 122.233 158.642 1.00 35.83  ? 138 ASN E O   1 
ATOM   11874 C CB  . ASN E 2 136 ? 133.534 119.862 157.544 1.00 35.83  ? 138 ASN E CB  1 
ATOM   11875 C CG  . ASN E 2 136 ? 133.675 118.417 157.141 1.00 35.83  ? 138 ASN E CG  1 
ATOM   11876 O OD1 . ASN E 2 136 ? 133.852 117.543 157.986 1.00 35.83  ? 138 ASN E OD1 1 
ATOM   11877 N ND2 . ASN E 2 136 ? 133.594 118.153 155.844 1.00 35.83  ? 138 ASN E ND2 1 
ATOM   11878 N N   . ILE E 2 137 ? 134.602 121.461 160.739 1.00 35.07  ? 139 ILE E N   1 
ATOM   11879 C CA  . ILE E 2 137 ? 135.312 122.680 161.239 1.00 35.07  ? 139 ILE E CA  1 
ATOM   11880 C C   . ILE E 2 137 ? 136.346 122.282 162.294 1.00 35.07  ? 139 ILE E C   1 
ATOM   11881 O O   . ILE E 2 137 ? 136.004 121.449 163.137 1.00 35.07  ? 139 ILE E O   1 
ATOM   11882 C CB  . ILE E 2 137 ? 134.313 123.691 161.825 1.00 35.07  ? 139 ILE E CB  1 
ATOM   11883 C CG1 . ILE E 2 137 ? 133.380 124.265 160.757 1.00 35.07  ? 139 ILE E CG1 1 
ATOM   11884 C CG2 . ILE E 2 137 ? 135.044 124.789 162.578 1.00 35.07  ? 139 ILE E CG2 1 
ATOM   11885 C CD1 . ILE E 2 137 ? 131.945 124.388 161.206 1.00 35.07  ? 139 ILE E CD1 1 
ATOM   11886 N N   . LEU E 2 138 ? 137.549 122.865 162.258 1.00 32.93  ? 140 LEU E N   1 
ATOM   11887 C CA  . LEU E 2 138 ? 138.626 122.561 163.242 1.00 32.93  ? 140 LEU E CA  1 
ATOM   11888 C C   . LEU E 2 138 ? 139.011 123.832 163.992 1.00 32.93  ? 140 LEU E C   1 
ATOM   11889 O O   . LEU E 2 138 ? 139.249 124.837 163.317 1.00 32.93  ? 140 LEU E O   1 
ATOM   11890 C CB  . LEU E 2 138 ? 139.851 122.043 162.493 1.00 50.00  ? 140 LEU E CB  1 
ATOM   11891 C CG  . LEU E 2 138 ? 141.151 122.069 163.289 1.00 50.00  ? 140 LEU E CG  1 
ATOM   11892 C CD1 . LEU E 2 138 ? 141.073 121.091 164.446 1.00 50.00  ? 140 LEU E CD1 1 
ATOM   11893 C CD2 . LEU E 2 138 ? 142.339 121.745 162.399 1.00 50.00  ? 140 LEU E CD2 1 
ATOM   11894 N N   . LEU E 2 139 ? 139.099 123.787 165.323 1.00 36.72  ? 141 LEU E N   1 
ATOM   11895 C CA  . LEU E 2 139 ? 139.378 125.029 166.090 1.00 36.72  ? 141 LEU E CA  1 
ATOM   11896 C C   . LEU E 2 139 ? 140.513 124.821 167.095 1.00 36.72  ? 141 LEU E C   1 
ATOM   11897 O O   . LEU E 2 139 ? 140.252 124.218 168.140 1.00 36.72  ? 141 LEU E O   1 
ATOM   11898 C CB  . LEU E 2 139 ? 138.101 125.478 166.803 1.00 36.72  ? 141 LEU E CB  1 
ATOM   11899 C CG  . LEU E 2 139 ? 138.052 126.963 167.151 1.00 36.72  ? 141 LEU E CG  1 
ATOM   11900 C CD1 . LEU E 2 139 ? 136.623 127.422 167.361 1.00 36.72  ? 141 LEU E CD1 1 
ATOM   11901 C CD2 . LEU E 2 139 ? 138.889 127.266 168.383 1.00 36.72  ? 141 LEU E CD2 1 
ATOM   11902 N N   . PHE E 2 140 ? 141.723 125.291 166.789 1.00 37.46  ? 142 PHE E N   1 
ATOM   11903 C CA  . PHE E 2 140 ? 142.825 125.245 167.739 1.00 37.46  ? 142 PHE E CA  1 
ATOM   11904 C C   . PHE E 2 140 ? 142.845 126.520 168.569 1.00 37.46  ? 142 PHE E C   1 
ATOM   11905 O O   . PHE E 2 140 ? 142.466 127.593 168.094 1.00 37.46  ? 142 PHE E O   1 
ATOM   11906 C CB  . PHE E 2 140 ? 144.186 125.090 167.041 1.00 37.46  ? 142 PHE E CB  1 
ATOM   11907 C CG  . PHE E 2 140 ? 144.479 123.699 166.550 1.00 37.46  ? 142 PHE E CG  1 
ATOM   11908 C CD1 . PHE E 2 140 ? 143.504 122.720 166.538 1.00 37.46  ? 142 PHE E CD1 1 
ATOM   11909 C CD2 . PHE E 2 140 ? 145.751 123.371 166.111 1.00 37.46  ? 142 PHE E CD2 1 
ATOM   11910 C CE1 . PHE E 2 140 ? 143.789 121.444 166.093 1.00 37.46  ? 142 PHE E CE1 1 
ATOM   11911 C CE2 . PHE E 2 140 ? 146.039 122.100 165.662 1.00 37.46  ? 142 PHE E CE2 1 
ATOM   11912 C CZ  . PHE E 2 140 ? 145.057 121.136 165.651 1.00 37.46  ? 142 PHE E CZ  1 
ATOM   11913 N N   . ILE E 2 141 ? 143.296 126.397 169.815 1.00 43.40  ? 143 ILE E N   1 
ATOM   11914 C CA  . ILE E 2 141 ? 143.493 127.538 170.701 1.00 43.40  ? 143 ILE E CA  1 
ATOM   11915 C C   . ILE E 2 141 ? 144.882 127.435 171.312 1.00 43.40  ? 143 ILE E C   1 
ATOM   11916 O O   . ILE E 2 141 ? 145.233 126.400 171.889 1.00 43.40  ? 143 ILE E O   1 
ATOM   11917 C CB  . ILE E 2 141 ? 142.424 127.599 171.806 1.00 43.40  ? 143 ILE E CB  1 
ATOM   11918 C CG1 . ILE E 2 141 ? 141.068 127.974 171.214 1.00 43.40  ? 143 ILE E CG1 1 
ATOM   11919 C CG2 . ILE E 2 141 ? 142.826 128.598 172.873 1.00 43.40  ? 143 ILE E CG2 1 
ATOM   11920 C CD1 . ILE E 2 141 ? 140.018 128.282 172.253 1.00 43.40  ? 143 ILE E CD1 1 
ATOM   11921 N N   . PHE E 2 142 ? 145.666 128.500 171.194 1.00 48.33  ? 144 PHE E N   1 
ATOM   11922 C CA  . PHE E 2 142 ? 147.018 128.532 171.729 1.00 48.33  ? 144 PHE E CA  1 
ATOM   11923 C C   . PHE E 2 142 ? 147.041 129.227 173.086 1.00 48.33  ? 144 PHE E C   1 
ATOM   11924 O O   . PHE E 2 142 ? 146.052 129.807 173.538 1.00 48.33  ? 144 PHE E O   1 
ATOM   11925 C CB  . PHE E 2 142 ? 147.968 129.229 170.754 1.00 48.33  ? 144 PHE E CB  1 
ATOM   11926 C CG  . PHE E 2 142 ? 147.973 128.630 169.380 1.00 48.33  ? 144 PHE E CG  1 
ATOM   11927 C CD1 . PHE E 2 142 ? 148.638 127.446 169.131 1.00 48.33  ? 144 PHE E CD1 1 
ATOM   11928 C CD2 . PHE E 2 142 ? 147.321 129.257 168.335 1.00 48.33  ? 144 PHE E CD2 1 
ATOM   11929 C CE1 . PHE E 2 142 ? 148.648 126.895 167.867 1.00 48.33  ? 144 PHE E CE1 1 
ATOM   11930 C CE2 . PHE E 2 142 ? 147.329 128.711 167.069 1.00 48.33  ? 144 PHE E CE2 1 
ATOM   11931 C CZ  . PHE E 2 142 ? 147.992 127.529 166.835 1.00 48.33  ? 144 PHE E CZ  1 
ATOM   11932 N N   . ARG E 2 143 ? 148.201 129.153 173.745 1.00 65.06  ? 145 ARG E N   1 
ATOM   11933 C CA  . ARG E 2 143 ? 148.337 129.739 175.075 1.00 65.06  ? 145 ARG E CA  1 
ATOM   11934 C C   . ARG E 2 143 ? 148.242 131.259 175.031 1.00 65.06  ? 145 ARG E C   1 
ATOM   11935 O O   . ARG E 2 143 ? 147.573 131.867 175.875 1.00 65.06  ? 145 ARG E O   1 
ATOM   11936 C CB  . ARG E 2 143 ? 149.659 129.310 175.708 1.00 65.06  ? 145 ARG E CB  1 
ATOM   11937 C CG  . ARG E 2 143 ? 149.832 127.809 175.845 1.00 65.06  ? 145 ARG E CG  1 
ATOM   11938 C CD  . ARG E 2 143 ? 151.163 127.469 176.496 1.00 65.06  ? 145 ARG E CD  1 
ATOM   11939 N NE  . ARG E 2 143 ? 151.305 128.100 177.802 1.00 65.06  ? 145 ARG E NE  1 
ATOM   11940 C CZ  . ARG E 2 143 ? 150.886 127.566 178.942 1.00 65.06  ? 145 ARG E CZ  1 
ATOM   11941 N NH1 . ARG E 2 143 ? 150.295 126.383 178.975 1.00 65.06  ? 145 ARG E NH1 1 
ATOM   11942 N NH2 . ARG E 2 143 ? 151.064 128.237 180.076 1.00 65.06  ? 145 ARG E NH2 1 
ATOM   11943 N N   . ASP E 2 144 ? 148.901 131.891 174.059 1.00 55.66  ? 146 ASP E N   1 
ATOM   11944 C CA  . ASP E 2 144 ? 148.952 133.347 174.007 1.00 55.66  ? 146 ASP E CA  1 
ATOM   11945 C C   . ASP E 2 144 ? 147.612 133.980 173.661 1.00 55.66  ? 146 ASP E C   1 
ATOM   11946 O O   . ASP E 2 144 ? 147.470 135.199 173.801 1.00 55.66  ? 146 ASP E O   1 
ATOM   11947 C CB  . ASP E 2 144 ? 150.013 133.800 173.002 1.00 55.66  ? 146 ASP E CB  1 
ATOM   11948 C CG  . ASP E 2 144 ? 149.901 133.083 171.674 1.00 55.66  ? 146 ASP E CG  1 
ATOM   11949 O OD1 . ASP E 2 144 ? 148.962 132.277 171.510 1.00 55.66  ? 146 ASP E OD1 1 
ATOM   11950 O OD2 . ASP E 2 144 ? 150.753 133.322 170.793 1.00 55.66  ? 146 ASP E OD2 1 
ATOM   11951 N N   . GLY E 2 145 ? 146.634 133.195 173.220 1.00 46.13  ? 147 GLY E N   1 
ATOM   11952 C CA  . GLY E 2 145 ? 145.321 133.704 172.883 1.00 46.13  ? 147 GLY E CA  1 
ATOM   11953 C C   . GLY E 2 145 ? 144.957 133.591 171.421 1.00 46.13  ? 147 GLY E C   1 
ATOM   11954 O O   . GLY E 2 145 ? 143.797 133.842 171.071 1.00 46.13  ? 147 GLY E O   1 
ATOM   11955 N N   . ASP E 2 146 ? 145.898 133.230 170.555 1.00 40.09  ? 148 ASP E N   1 
ATOM   11956 C CA  . ASP E 2 146 ? 145.576 133.048 169.149 1.00 40.09  ? 148 ASP E CA  1 
ATOM   11957 C C   . ASP E 2 146 ? 144.659 131.846 168.972 1.00 40.09  ? 148 ASP E C   1 
ATOM   11958 O O   . ASP E 2 146 ? 144.844 130.805 169.607 1.00 40.09  ? 148 ASP E O   1 
ATOM   11959 C CB  . ASP E 2 146 ? 146.849 132.857 168.328 1.00 40.09  ? 148 ASP E CB  1 
ATOM   11960 C CG  . ASP E 2 146 ? 147.843 133.978 168.528 1.00 40.09  ? 148 ASP E CG  1 
ATOM   11961 O OD1 . ASP E 2 146 ? 147.864 134.562 169.631 1.00 40.09  ? 148 ASP E OD1 1 
ATOM   11962 O OD2 . ASP E 2 146 ? 148.602 134.277 167.583 1.00 40.09  ? 148 ASP E OD2 1 
ATOM   11963 N N   . VAL E 2 147 ? 143.663 131.994 168.105 1.00 33.25  ? 149 VAL E N   1 
ATOM   11964 C CA  . VAL E 2 147 ? 142.722 130.929 167.791 1.00 33.25  ? 149 VAL E CA  1 
ATOM   11965 C C   . VAL E 2 147 ? 142.732 130.717 166.286 1.00 33.25  ? 149 VAL E C   1 
ATOM   11966 O O   . VAL E 2 147 ? 142.545 131.668 165.520 1.00 33.25  ? 149 VAL E O   1 
ATOM   11967 C CB  . VAL E 2 147 ? 141.305 131.257 168.294 1.00 33.25  ? 149 VAL E CB  1 
ATOM   11968 C CG1 . VAL E 2 147 ? 141.049 132.745 168.207 1.00 33.25  ? 149 VAL E CG1 1 
ATOM   11969 C CG2 . VAL E 2 147 ? 140.268 130.499 167.491 1.00 33.25  ? 149 VAL E CG2 1 
ATOM   11970 N N   . LEU E 2 148 ? 142.954 129.477 165.865 1.00 31.24  ? 150 LEU E N   1 
ATOM   11971 C CA  . LEU E 2 148 ? 143.003 129.119 164.455 1.00 31.24  ? 150 LEU E CA  1 
ATOM   11972 C C   . LEU E 2 148 ? 141.737 128.362 164.090 1.00 31.24  ? 150 LEU E C   1 
ATOM   11973 O O   . LEU E 2 148 ? 141.420 127.342 164.708 1.00 31.24  ? 150 LEU E O   1 
ATOM   11974 C CB  . LEU E 2 148 ? 144.237 128.270 164.149 1.00 31.24  ? 150 LEU E CB  1 
ATOM   11975 C CG  . LEU E 2 148 ? 144.363 127.706 162.733 1.00 31.24  ? 150 LEU E CG  1 
ATOM   11976 C CD1 . LEU E 2 148 ? 145.757 127.951 162.187 1.00 31.24  ? 150 LEU E CD1 1 
ATOM   11977 C CD2 . LEU E 2 148 ? 144.046 126.225 162.716 1.00 31.24  ? 150 LEU E CD2 1 
ATOM   11978 N N   . VAL E 2 149 ? 141.020 128.858 163.088 1.00 30.15  ? 151 VAL E N   1 
ATOM   11979 C CA  . VAL E 2 149 ? 139.779 128.251 162.627 1.00 30.15  ? 151 VAL E CA  1 
ATOM   11980 C C   . VAL E 2 149 ? 139.980 127.804 161.190 1.00 30.15  ? 151 VAL E C   1 
ATOM   11981 O O   . VAL E 2 149 ? 140.288 128.623 160.317 1.00 30.15  ? 151 VAL E O   1 
ATOM   11982 C CB  . VAL E 2 149 ? 138.594 129.222 162.732 1.00 30.15  ? 151 VAL E CB  1 
ATOM   11983 C CG1 . VAL E 2 149 ? 137.421 128.708 161.922 1.00 30.15  ? 151 VAL E CG1 1 
ATOM   11984 C CG2 . VAL E 2 149 ? 138.198 129.412 164.180 1.00 30.15  ? 151 VAL E CG2 1 
ATOM   11985 N N   . SER E 2 150 ? 139.806 126.510 160.944 1.00 32.97  ? 152 SER E N   1 
ATOM   11986 C CA  . SER E 2 150 ? 139.878 125.948 159.604 1.00 32.97  ? 152 SER E CA  1 
ATOM   11987 C C   . SER E 2 150 ? 138.569 125.239 159.306 1.00 32.97  ? 152 SER E C   1 
ATOM   11988 O O   . SER E 2 150 ? 138.114 124.412 160.101 1.00 32.97  ? 152 SER E O   1 
ATOM   11989 C CB  . SER E 2 150 ? 141.045 124.974 159.470 1.00 32.97  ? 152 SER E CB  1 
ATOM   11990 O OG  . SER E 2 150 ? 140.741 123.737 160.086 1.00 32.97  ? 152 SER E OG  1 
ATOM   11991 N N   . MET E 2 151 ? 137.971 125.559 158.164 1.00 42.40  ? 153 MET E N   1 
ATOM   11992 C CA  . MET E 2 151 ? 136.690 124.986 157.789 1.00 42.40  ? 153 MET E CA  1 
ATOM   11993 C C   . MET E 2 151 ? 136.737 124.561 156.333 1.00 42.40  ? 153 MET E C   1 
ATOM   11994 O O   . MET E 2 151 ? 137.480 125.126 155.529 1.00 42.40  ? 153 MET E O   1 
ATOM   11995 C CB  . MET E 2 151 ? 135.555 125.982 158.011 1.00 42.40  ? 153 MET E CB  1 
ATOM   11996 C CG  . MET E 2 151 ? 135.886 127.381 157.551 1.00 42.40  ? 153 MET E CG  1 
ATOM   11997 S SD  . MET E 2 151 ? 134.457 128.469 157.593 1.00 42.40  ? 153 MET E SD  1 
ATOM   11998 C CE  . MET E 2 151 ? 133.470 127.666 158.847 1.00 42.40  ? 153 MET E CE  1 
ATOM   11999 N N   . ARG E 2 152 ? 135.932 123.560 156.000 1.00 47.29  ? 154 ARG E N   1 
ATOM   12000 C CA  . ARG E 2 152 ? 135.874 123.039 154.644 1.00 47.29  ? 154 ARG E CA  1 
ATOM   12001 C C   . ARG E 2 152 ? 134.744 123.723 153.891 1.00 47.29  ? 154 ARG E C   1 
ATOM   12002 O O   . ARG E 2 152 ? 133.600 123.732 154.353 1.00 47.29  ? 154 ARG E O   1 
ATOM   12003 C CB  . ARG E 2 152 ? 135.666 121.527 154.656 1.00 47.29  ? 154 ARG E CB  1 
ATOM   12004 C CG  . ARG E 2 152 ? 135.583 120.912 153.279 1.00 47.29  ? 154 ARG E CG  1 
ATOM   12005 C CD  . ARG E 2 152 ? 135.882 119.429 153.323 1.00 47.29  ? 154 ARG E CD  1 
ATOM   12006 N NE  . ARG E 2 152 ? 136.279 118.933 152.013 1.00 47.29  ? 154 ARG E NE  1 
ATOM   12007 C CZ  . ARG E 2 152 ? 135.557 118.099 151.280 1.00 47.29  ? 154 ARG E CZ  1 
ATOM   12008 N NH1 . ARG E 2 152 ? 134.401 117.624 151.710 1.00 47.29  ? 154 ARG E NH1 1 
ATOM   12009 N NH2 . ARG E 2 152 ? 136.008 117.730 150.085 1.00 47.29  ? 154 ARG E NH2 1 
ATOM   12010 N N   . LEU E 2 153 ? 135.065 124.290 152.735 1.00 47.29  ? 155 LEU E N   1 
ATOM   12011 C CA  . LEU E 2 153 ? 134.106 125.045 151.948 1.00 47.29  ? 155 LEU E CA  1 
ATOM   12012 C C   . LEU E 2 153 ? 134.068 124.501 150.530 1.00 47.29  ? 155 LEU E C   1 
ATOM   12013 O O   . LEU E 2 153 ? 135.031 123.897 150.054 1.00 47.29  ? 155 LEU E O   1 
ATOM   12014 C CB  . LEU E 2 153 ? 134.458 126.532 151.913 1.00 47.29  ? 155 LEU E CB  1 
ATOM   12015 C CG  . LEU E 2 153 ? 133.683 127.467 152.834 1.00 47.29  ? 155 LEU E CG  1 
ATOM   12016 C CD1 . LEU E 2 153 ? 133.757 126.990 154.266 1.00 47.29  ? 155 LEU E CD1 1 
ATOM   12017 C CD2 . LEU E 2 153 ? 134.227 128.873 152.718 1.00 47.29  ? 155 LEU E CD2 1 
ATOM   12018 N N   . SER E 2 154 ? 132.939 124.717 149.860 1.00 33.62  ? 156 SER E N   1 
ATOM   12019 C CA  . SER E 2 154 ? 132.765 124.358 148.453 1.00 33.62  ? 156 SER E CA  1 
ATOM   12020 C C   . SER E 2 154 ? 132.101 125.547 147.769 1.00 33.62  ? 156 SER E C   1 
ATOM   12021 O O   . SER E 2 154 ? 130.873 125.617 147.685 1.00 33.62  ? 156 SER E O   1 
ATOM   12022 C CB  . SER E 2 154 ? 131.943 123.088 148.305 1.00 33.62  ? 156 SER E CB  1 
ATOM   12023 O OG  . SER E 2 154 ? 131.583 122.875 146.953 1.00 33.62  ? 156 SER E OG  1 
ATOM   12024 N N   . ILE E 2 155 ? 132.912 126.475 147.278 1.00 32.44  ? 157 ILE E N   1 
ATOM   12025 C CA  . ILE E 2 155 ? 132.415 127.690 146.663 1.00 32.44  ? 157 ILE E CA  1 
ATOM   12026 C C   . ILE E 2 155 ? 132.387 127.507 145.153 1.00 32.44  ? 157 ILE E C   1 
ATOM   12027 O O   . ILE E 2 155 ? 133.115 126.693 144.582 1.00 32.44  ? 157 ILE E O   1 
ATOM   12028 C CB  . ILE E 2 155 ? 133.264 128.915 147.057 1.00 32.44  ? 157 ILE E CB  1 
ATOM   12029 C CG1 . ILE E 2 155 ? 134.746 128.569 147.006 1.00 32.44  ? 157 ILE E CG1 1 
ATOM   12030 C CG2 . ILE E 2 155 ? 132.904 129.387 148.446 1.00 32.44  ? 157 ILE E CG2 1 
ATOM   12031 C CD1 . ILE E 2 155 ? 135.627 129.631 147.607 1.00 32.44  ? 157 ILE E CD1 1 
ATOM   12032 N N   . THR E 2 156 ? 131.530 128.284 144.493 1.00 31.42  ? 158 THR E N   1 
ATOM   12033 C CA  . THR E 2 156 ? 131.376 128.254 143.038 1.00 31.42  ? 158 THR E CA  1 
ATOM   12034 C C   . THR E 2 156 ? 131.556 129.681 142.535 1.00 31.42  ? 158 THR E C   1 
ATOM   12035 O O   . THR E 2 156 ? 130.586 130.428 142.388 1.00 31.42  ? 158 THR E O   1 
ATOM   12036 C CB  . THR E 2 156 ? 130.028 127.684 142.636 1.00 31.42  ? 158 THR E CB  1 
ATOM   12037 O OG1 . THR E 2 156 ? 129.841 126.414 143.270 1.00 31.42  ? 158 THR E OG1 1 
ATOM   12038 C CG2 . THR E 2 156 ? 129.958 127.506 141.132 1.00 31.42  ? 158 THR E CG2 1 
ATOM   12039 N N   . LEU E 2 157 ? 132.801 130.051 142.269 1.00 32.59  ? 159 LEU E N   1 
ATOM   12040 C CA  . LEU E 2 157 ? 133.134 131.406 141.866 1.00 32.59  ? 159 LEU E CA  1 
ATOM   12041 C C   . LEU E 2 157 ? 132.901 131.598 140.376 1.00 32.59  ? 159 LEU E C   1 
ATOM   12042 O O   . LEU E 2 157 ? 133.056 130.671 139.579 1.00 32.59  ? 159 LEU E O   1 
ATOM   12043 C CB  . LEU E 2 157 ? 134.592 131.702 142.193 1.00 32.59  ? 159 LEU E CB  1 
ATOM   12044 C CG  . LEU E 2 157 ? 135.071 131.078 143.498 1.00 32.59  ? 159 LEU E CG  1 
ATOM   12045 C CD1 . LEU E 2 157 ? 136.535 131.350 143.674 1.00 32.59  ? 159 LEU E CD1 1 
ATOM   12046 C CD2 . LEU E 2 157 ? 134.289 131.639 144.666 1.00 32.59  ? 159 LEU E CD2 1 
ATOM   12047 N N   . SER E 2 158 ? 132.541 132.821 140.000 1.00 36.32  ? 160 SER E N   1 
ATOM   12048 C CA  . SER E 2 158 ? 132.356 133.192 138.604 1.00 36.32  ? 160 SER E CA  1 
ATOM   12049 C C   . SER E 2 158 ? 133.470 134.137 138.185 1.00 36.32  ? 160 SER E C   1 
ATOM   12050 O O   . SER E 2 158 ? 133.739 135.127 138.872 1.00 36.32  ? 160 SER E O   1 
ATOM   12051 C CB  . SER E 2 158 ? 130.998 133.856 138.386 1.00 36.32  ? 160 SER E CB  1 
ATOM   12052 O OG  . SER E 2 158 ? 131.052 135.230 138.725 1.00 36.32  ? 160 SER E OG  1 
ATOM   12053 N N   . CYS E 2 159 ? 134.114 133.833 137.061 1.00 43.44  ? 161 CYS E N   1 
ATOM   12054 C CA  . CYS E 2 159 ? 135.185 134.669 136.528 1.00 43.44  ? 161 CYS E CA  1 
ATOM   12055 C C   . CYS E 2 159 ? 134.851 135.034 135.089 1.00 43.44  ? 161 CYS E C   1 
ATOM   12056 O O   . CYS E 2 159 ? 134.800 134.139 134.221 1.00 43.44  ? 161 CYS E O   1 
ATOM   12057 C CB  . CYS E 2 159 ? 136.536 133.958 136.609 1.00 43.44  ? 161 CYS E CB  1 
ATOM   12058 S SG  . CYS E 2 159 ? 136.517 132.218 136.138 1.00 43.44  ? 161 CYS E SG  1 
ATOM   12059 N N   . PRO E 2 160 ? 134.619 136.312 134.781 1.00 47.68  ? 162 PRO E N   1 
ATOM   12060 C CA  . PRO E 2 160 ? 134.374 136.700 133.387 1.00 47.68  ? 162 PRO E CA  1 
ATOM   12061 C C   . PRO E 2 160 ? 135.603 136.464 132.527 1.00 47.68  ? 162 PRO E C   1 
ATOM   12062 O O   . PRO E 2 160 ? 136.639 137.108 132.715 1.00 47.68  ? 162 PRO E O   1 
ATOM   12063 C CB  . PRO E 2 160 ? 134.026 138.189 133.490 1.00 47.68  ? 162 PRO E CB  1 
ATOM   12064 C CG  . PRO E 2 160 ? 134.662 138.638 134.759 1.00 47.68  ? 162 PRO E CG  1 
ATOM   12065 C CD  . PRO E 2 160 ? 134.596 137.467 135.693 1.00 47.68  ? 162 PRO E CD  1 
ATOM   12066 N N   . LEU E 2 161 ? 135.495 135.539 131.581 1.00 49.98  ? 163 LEU E N   1 
ATOM   12067 C CA  . LEU E 2 161 ? 136.629 135.085 130.793 1.00 49.98  ? 163 LEU E CA  1 
ATOM   12068 C C   . LEU E 2 161 ? 136.538 135.635 129.375 1.00 49.98  ? 163 LEU E C   1 
ATOM   12069 O O   . LEU E 2 161 ? 135.463 135.639 128.765 1.00 49.98  ? 163 LEU E O   1 
ATOM   12070 C CB  . LEU E 2 161 ? 136.699 133.553 130.777 1.00 49.98  ? 163 LEU E CB  1 
ATOM   12071 C CG  . LEU E 2 161 ? 135.768 132.732 129.882 1.00 49.98  ? 163 LEU E CG  1 
ATOM   12072 C CD1 . LEU E 2 161 ? 136.204 131.276 129.868 1.00 49.98  ? 163 LEU E CD1 1 
ATOM   12073 C CD2 . LEU E 2 161 ? 134.321 132.848 130.324 1.00 49.98  ? 163 LEU E CD2 1 
ATOM   12074 N N   . ASP E 2 162 ? 137.667 136.121 128.866 1.00 51.49  ? 164 ASP E N   1 
ATOM   12075 C CA  . ASP E 2 162 ? 137.744 136.662 127.517 1.00 51.49  ? 164 ASP E CA  1 
ATOM   12076 C C   . ASP E 2 162 ? 138.041 135.550 126.523 1.00 51.49  ? 164 ASP E C   1 
ATOM   12077 O O   . ASP E 2 162 ? 138.806 134.627 126.815 1.00 51.49  ? 164 ASP E O   1 
ATOM   12078 C CB  . ASP E 2 162 ? 138.819 137.745 127.428 1.00 51.49  ? 164 ASP E CB  1 
ATOM   12079 C CG  . ASP E 2 162 ? 140.207 137.214 127.726 1.00 51.49  ? 164 ASP E CG  1 
ATOM   12080 O OD1 . ASP E 2 162 ? 140.841 136.652 126.809 1.00 51.49  ? 164 ASP E OD1 1 
ATOM   12081 O OD2 . ASP E 2 162 ? 140.667 137.362 128.877 1.00 51.49  ? 164 ASP E OD2 1 
ATOM   12082 N N   . LEU E 2 163 ? 137.434 135.644 125.345 1.00 55.83  ? 165 LEU E N   1 
ATOM   12083 C CA  . LEU E 2 163 ? 137.555 134.617 124.320 1.00 55.83  ? 165 LEU E CA  1 
ATOM   12084 C C   . LEU E 2 163 ? 137.910 135.230 122.974 1.00 55.83  ? 165 LEU E C   1 
ATOM   12085 O O   . LEU E 2 163 ? 137.460 134.765 121.924 1.00 55.83  ? 165 LEU E O   1 
ATOM   12086 C CB  . LEU E 2 163 ? 136.270 133.801 124.216 1.00 55.83  ? 165 LEU E CB  1 
ATOM   12087 C CG  . LEU E 2 163 ? 135.873 133.008 125.461 1.00 55.83  ? 165 LEU E CG  1 
ATOM   12088 C CD1 . LEU E 2 163 ? 134.550 132.295 125.244 1.00 55.83  ? 165 LEU E CD1 1 
ATOM   12089 C CD2 . LEU E 2 163 ? 136.962 132.018 125.828 1.00 55.83  ? 165 LEU E CD2 1 
ATOM   12090 N N   . THR E 2 164 ? 138.720 136.291 122.983 1.00 54.63  ? 166 THR E N   1 
ATOM   12091 C CA  . THR E 2 164 ? 139.161 136.884 121.723 1.00 54.63  ? 166 THR E CA  1 
ATOM   12092 C C   . THR E 2 164 ? 139.991 135.894 120.918 1.00 54.63  ? 166 THR E C   1 
ATOM   12093 O O   . THR E 2 164 ? 139.822 135.775 119.698 1.00 54.63  ? 166 THR E O   1 
ATOM   12094 C CB  . THR E 2 164 ? 139.959 138.159 121.987 1.00 54.63  ? 166 THR E CB  1 
ATOM   12095 O OG1 . THR E 2 164 ? 139.209 139.025 122.846 1.00 54.63  ? 166 THR E OG1 1 
ATOM   12096 C CG2 . THR E 2 164 ? 140.246 138.880 120.681 1.00 54.63  ? 166 THR E CG2 1 
ATOM   12097 N N   . LEU E 2 165 ? 140.889 135.175 121.583 1.00 49.47  ? 167 LEU E N   1 
ATOM   12098 C CA  . LEU E 2 165 ? 141.641 134.072 120.991 1.00 49.47  ? 167 LEU E CA  1 
ATOM   12099 C C   . LEU E 2 165 ? 141.267 132.830 121.791 1.00 49.47  ? 167 LEU E C   1 
ATOM   12100 O O   . LEU E 2 165 ? 141.863 132.551 122.835 1.00 49.47  ? 167 LEU E O   1 
ATOM   12101 C CB  . LEU E 2 165 ? 143.147 134.340 121.005 1.00 49.47  ? 167 LEU E CB  1 
ATOM   12102 C CG  . LEU E 2 165 ? 143.807 135.023 122.207 1.00 49.47  ? 167 LEU E CG  1 
ATOM   12103 C CD1 . LEU E 2 165 ? 145.275 134.651 122.265 1.00 49.47  ? 167 LEU E CD1 1 
ATOM   12104 C CD2 . LEU E 2 165 ? 143.668 136.533 122.133 1.00 49.47  ? 167 LEU E CD2 1 
ATOM   12105 N N   . PHE E 2 166 ? 140.273 132.092 121.309 1.00 55.19  ? 168 PHE E N   1 
ATOM   12106 C CA  . PHE E 2 166 ? 139.628 131.068 122.121 1.00 55.19  ? 168 PHE E CA  1 
ATOM   12107 C C   . PHE E 2 166 ? 140.468 129.803 122.300 1.00 55.19  ? 168 PHE E C   1 
ATOM   12108 O O   . PHE E 2 166 ? 140.723 129.414 123.446 1.00 55.19  ? 168 PHE E O   1 
ATOM   12109 C CB  . PHE E 2 166 ? 138.260 130.714 121.534 1.00 55.19  ? 168 PHE E CB  1 
ATOM   12110 C CG  . PHE E 2 166 ? 137.768 129.363 121.940 1.00 55.19  ? 168 PHE E CG  1 
ATOM   12111 C CD1 . PHE E 2 166 ? 137.324 129.137 123.228 1.00 55.19  ? 168 PHE E CD1 1 
ATOM   12112 C CD2 . PHE E 2 166 ? 137.752 128.318 121.037 1.00 55.19  ? 168 PHE E CD2 1 
ATOM   12113 C CE1 . PHE E 2 166 ? 136.873 127.896 123.608 1.00 55.19  ? 168 PHE E CE1 1 
ATOM   12114 C CE2 . PHE E 2 166 ? 137.301 127.074 121.412 1.00 55.19  ? 168 PHE E CE2 1 
ATOM   12115 C CZ  . PHE E 2 166 ? 136.861 126.863 122.699 1.00 55.19  ? 168 PHE E CZ  1 
ATOM   12116 N N   . PRO E 2 167 ? 140.900 129.118 121.232 1.00 55.10  ? 169 PRO E N   1 
ATOM   12117 C CA  . PRO E 2 167 ? 141.587 127.831 121.439 1.00 55.10  ? 169 PRO E CA  1 
ATOM   12118 C C   . PRO E 2 167 ? 142.848 127.937 122.276 1.00 55.10  ? 169 PRO E C   1 
ATOM   12119 O O   . PRO E 2 167 ? 143.160 127.003 123.023 1.00 55.10  ? 169 PRO E O   1 
ATOM   12120 C CB  . PRO E 2 167 ? 141.895 127.364 120.011 1.00 55.10  ? 169 PRO E CB  1 
ATOM   12121 C CG  . PRO E 2 167 ? 140.941 128.107 119.155 1.00 55.10  ? 169 PRO E CG  1 
ATOM   12122 C CD  . PRO E 2 167 ? 140.830 129.446 119.799 1.00 55.10  ? 169 PRO E CD  1 
ATOM   12123 N N   . MET E 2 168 ? 143.587 129.039 122.176 1.00 56.16  ? 170 MET E N   1 
ATOM   12124 C CA  . MET E 2 168 ? 144.753 129.280 123.017 1.00 56.16  ? 170 MET E CA  1 
ATOM   12125 C C   . MET E 2 168 ? 144.558 130.601 123.749 1.00 56.16  ? 170 MET E C   1 
ATOM   12126 O O   . MET E 2 168 ? 144.413 131.652 123.118 1.00 56.16  ? 170 MET E O   1 
ATOM   12127 C CB  . MET E 2 168 ? 146.044 129.271 122.190 1.00 56.16  ? 170 MET E CB  1 
ATOM   12128 C CG  . MET E 2 168 ? 146.136 130.329 121.100 1.00 56.16  ? 170 MET E CG  1 
ATOM   12129 S SD  . MET E 2 168 ? 145.111 129.960 119.665 1.00 56.16  ? 170 MET E SD  1 
ATOM   12130 C CE  . MET E 2 168 ? 146.176 128.830 118.775 1.00 56.16  ? 170 MET E CE  1 
ATOM   12131 N N   . ASP E 2 169 ? 144.533 130.541 125.078 1.00 51.16  ? 171 ASP E N   1 
ATOM   12132 C CA  . ASP E 2 169 ? 144.270 131.722 125.887 1.00 51.16  ? 171 ASP E CA  1 
ATOM   12133 C C   . ASP E 2 169 ? 144.702 131.446 127.317 1.00 51.16  ? 171 ASP E C   1 
ATOM   12134 O O   . ASP E 2 169 ? 144.897 130.296 127.715 1.00 51.16  ? 171 ASP E O   1 
ATOM   12135 C CB  . ASP E 2 169 ? 142.791 132.112 125.843 1.00 51.16  ? 171 ASP E CB  1 
ATOM   12136 C CG  . ASP E 2 169 ? 141.875 130.913 125.957 1.00 51.16  ? 171 ASP E CG  1 
ATOM   12137 O OD1 . ASP E 2 169 ? 142.376 129.775 125.858 1.00 51.16  ? 171 ASP E OD1 1 
ATOM   12138 O OD2 . ASP E 2 169 ? 140.656 131.106 126.146 1.00 51.16  ? 171 ASP E OD2 1 
ATOM   12139 N N   . THR E 2 170 ? 144.844 132.520 128.087 1.00 46.19  ? 172 THR E N   1 
ATOM   12140 C CA  . THR E 2 170 ? 145.224 132.444 129.495 1.00 46.19  ? 172 THR E CA  1 
ATOM   12141 C C   . THR E 2 170 ? 144.149 133.161 130.306 1.00 46.19  ? 172 THR E C   1 
ATOM   12142 O O   . THR E 2 170 ? 144.192 134.382 130.469 1.00 46.19  ? 172 THR E O   1 
ATOM   12143 C CB  . THR E 2 170 ? 146.601 133.057 129.736 1.00 46.19  ? 172 THR E CB  1 
ATOM   12144 O OG1 . THR E 2 170 ? 146.552 134.463 129.464 1.00 46.19  ? 172 THR E OG1 1 
ATOM   12145 C CG2 . THR E 2 170 ? 147.638 132.412 128.835 1.00 46.19  ? 172 THR E CG2 1 
ATOM   12146 N N   . GLN E 2 171 ? 143.182 132.400 130.811 1.00 43.08  ? 173 GLN E N   1 
ATOM   12147 C CA  . GLN E 2 171 ? 142.151 132.983 131.655 1.00 43.08  ? 173 GLN E CA  1 
ATOM   12148 C C   . GLN E 2 171 ? 142.726 133.371 133.010 1.00 43.08  ? 173 GLN E C   1 
ATOM   12149 O O   . GLN E 2 171 ? 143.681 132.765 133.503 1.00 43.08  ? 173 GLN E O   1 
ATOM   12150 C CB  . GLN E 2 171 ? 140.992 132.007 131.844 1.00 43.08  ? 173 GLN E CB  1 
ATOM   12151 C CG  . GLN E 2 171 ? 140.341 131.559 130.556 1.00 43.08  ? 173 GLN E CG  1 
ATOM   12152 C CD  . GLN E 2 171 ? 140.412 132.615 129.479 1.00 43.08  ? 173 GLN E CD  1 
ATOM   12153 O OE1 . GLN E 2 171 ? 141.145 132.471 128.506 1.00 43.08  ? 173 GLN E OE1 1 
ATOM   12154 N NE2 . GLN E 2 171 ? 139.656 133.689 129.651 1.00 43.08  ? 173 GLN E NE2 1 
ATOM   12155 N N   . ARG E 2 172 ? 142.135 134.396 133.613 1.00 37.00  ? 174 ARG E N   1 
ATOM   12156 C CA  . ARG E 2 172 ? 142.528 134.871 134.935 1.00 37.00  ? 174 ARG E CA  1 
ATOM   12157 C C   . ARG E 2 172 ? 141.295 134.826 135.830 1.00 37.00  ? 174 ARG E C   1 
ATOM   12158 O O   . ARG E 2 172 ? 140.583 135.822 135.975 1.00 37.00  ? 174 ARG E O   1 
ATOM   12159 C CB  . ARG E 2 172 ? 143.119 136.272 134.863 1.00 37.00  ? 174 ARG E CB  1 
ATOM   12160 C CG  . ARG E 2 172 ? 144.486 136.330 134.212 1.00 37.00  ? 174 ARG E CG  1 
ATOM   12161 C CD  . ARG E 2 172 ? 145.489 137.029 135.110 1.00 37.00  ? 174 ARG E CD  1 
ATOM   12162 N NE  . ARG E 2 172 ? 144.994 138.319 135.575 1.00 37.00  ? 174 ARG E NE  1 
ATOM   12163 C CZ  . ARG E 2 172 ? 145.639 139.107 136.424 1.00 37.00  ? 174 ARG E CZ  1 
ATOM   12164 N NH1 . ARG E 2 172 ? 146.813 138.765 136.928 1.00 37.00  ? 174 ARG E NH1 1 
ATOM   12165 N NH2 . ARG E 2 172 ? 145.092 140.266 136.776 1.00 37.00  ? 174 ARG E NH2 1 
ATOM   12166 N N   . CYS E 2 173 ? 141.044 133.667 136.430 1.00 34.04  ? 175 CYS E N   1 
ATOM   12167 C CA  . CYS E 2 173 ? 139.932 133.504 137.353 1.00 34.04  ? 175 CYS E CA  1 
ATOM   12168 C C   . CYS E 2 173 ? 140.411 133.811 138.765 1.00 34.04  ? 175 CYS E C   1 
ATOM   12169 O O   . CYS E 2 173 ? 141.491 133.368 139.169 1.00 34.04  ? 175 CYS E O   1 
ATOM   12170 C CB  . CYS E 2 173 ? 139.359 132.091 137.263 1.00 34.04  ? 175 CYS E CB  1 
ATOM   12171 S SG  . CYS E 2 173 ? 138.457 131.775 135.724 1.00 34.04  ? 175 CYS E SG  1 
ATOM   12172 N N   . LYS E 2 174 ? 139.609 134.566 139.510 1.00 31.75  ? 176 LYS E N   1 
ATOM   12173 C CA  . LYS E 2 174 ? 140.074 135.224 140.721 1.00 31.75  ? 176 LYS E CA  1 
ATOM   12174 C C   . LYS E 2 174 ? 139.180 134.900 141.909 1.00 31.75  ? 176 LYS E C   1 
ATOM   12175 O O   . LYS E 2 174 ? 137.979 134.660 141.762 1.00 31.75  ? 176 LYS E O   1 
ATOM   12176 C CB  . LYS E 2 174 ? 140.130 136.737 140.514 1.00 31.75  ? 176 LYS E CB  1 
ATOM   12177 C CG  . LYS E 2 174 ? 138.931 137.279 139.760 1.00 31.75  ? 176 LYS E CG  1 
ATOM   12178 C CD  . LYS E 2 174 ? 139.270 138.552 139.007 1.00 31.75  ? 176 LYS E CD  1 
ATOM   12179 C CE  . LYS E 2 174 ? 139.968 139.554 139.901 1.00 31.75  ? 176 LYS E CE  1 
ATOM   12180 N NZ  . LYS E 2 174 ? 140.445 140.743 139.144 1.00 31.75  ? 176 LYS E NZ  1 
ATOM   12181 N N   . MET E 2 175 ? 139.790 134.907 143.090 1.00 31.77  ? 177 MET E N   1 
ATOM   12182 C CA  . MET E 2 175 ? 139.098 134.774 144.365 1.00 31.77  ? 177 MET E CA  1 
ATOM   12183 C C   . MET E 2 175 ? 139.182 136.095 145.112 1.00 31.77  ? 177 MET E C   1 
ATOM   12184 O O   . MET E 2 175 ? 140.260 136.692 145.199 1.00 31.77  ? 177 MET E O   1 
ATOM   12185 C CB  . MET E 2 175 ? 139.711 133.662 145.217 1.00 31.77  ? 177 MET E CB  1 
ATOM   12186 C CG  . MET E 2 175 ? 138.698 132.806 145.946 1.00 31.77  ? 177 MET E CG  1 
ATOM   12187 S SD  . MET E 2 175 ? 139.434 131.423 146.833 1.00 31.77  ? 177 MET E SD  1 
ATOM   12188 C CE  . MET E 2 175 ? 140.155 130.504 145.483 1.00 31.77  ? 177 MET E CE  1 
ATOM   12189 N N   . GLN E 2 176 ? 138.055 136.549 145.651 1.00 31.08  ? 178 GLN E N   1 
ATOM   12190 C CA  . GLN E 2 176 ? 137.996 137.807 146.390 1.00 31.08  ? 178 GLN E CA  1 
ATOM   12191 C C   . GLN E 2 176 ? 137.382 137.551 147.762 1.00 31.08  ? 178 GLN E C   1 
ATOM   12192 O O   . GLN E 2 176 ? 136.175 137.711 147.953 1.00 31.08  ? 178 GLN E O   1 
ATOM   12193 C CB  . GLN E 2 176 ? 137.206 138.857 145.621 1.00 31.08  ? 178 GLN E CB  1 
ATOM   12194 C CG  . GLN E 2 176 ? 137.895 139.355 144.369 1.00 31.08  ? 178 GLN E CG  1 
ATOM   12195 C CD  . GLN E 2 176 ? 137.242 140.597 143.806 1.00 31.08  ? 178 GLN E CD  1 
ATOM   12196 O OE1 . GLN E 2 176 ? 136.499 141.288 144.500 1.00 31.08  ? 178 GLN E OE1 1 
ATOM   12197 N NE2 . GLN E 2 176 ? 137.512 140.886 142.540 1.00 31.08  ? 178 GLN E NE2 1 
ATOM   12198 N N   . LEU E 2 177 ? 138.217 137.156 148.717 1.00 30.09  ? 179 LEU E N   1 
ATOM   12199 C CA  . LEU E 2 177 ? 137.787 137.122 150.105 1.00 30.09  ? 179 LEU E CA  1 
ATOM   12200 C C   . LEU E 2 177 ? 137.567 138.542 150.605 1.00 30.09  ? 179 LEU E C   1 
ATOM   12201 O O   . LEU E 2 177 ? 138.255 139.478 150.193 1.00 30.09  ? 179 LEU E O   1 
ATOM   12202 C CB  . LEU E 2 177 ? 138.825 136.419 150.975 1.00 30.09  ? 179 LEU E CB  1 
ATOM   12203 C CG  . LEU E 2 177 ? 139.025 134.923 150.752 1.00 30.09  ? 179 LEU E CG  1 
ATOM   12204 C CD1 . LEU E 2 177 ? 140.078 134.671 149.692 1.00 30.09  ? 179 LEU E CD1 1 
ATOM   12205 C CD2 . LEU E 2 177 ? 139.411 134.258 152.051 1.00 30.09  ? 179 LEU E CD2 1 
ATOM   12206 N N   . GLU E 2 178 ? 136.597 138.704 151.499 1.00 33.70  ? 180 GLU E N   1 
ATOM   12207 C CA  . GLU E 2 178 ? 136.233 140.039 151.946 1.00 33.70  ? 180 GLU E CA  1 
ATOM   12208 C C   . GLU E 2 178 ? 135.373 139.938 153.195 1.00 33.70  ? 180 GLU E C   1 
ATOM   12209 O O   . GLU E 2 178 ? 134.491 139.082 153.276 1.00 33.70  ? 180 GLU E O   1 
ATOM   12210 C CB  . GLU E 2 178 ? 135.483 140.795 150.844 1.00 33.70  ? 180 GLU E CB  1 
ATOM   12211 C CG  . GLU E 2 178 ? 134.919 142.134 151.263 1.00 33.70  ? 180 GLU E CG  1 
ATOM   12212 C CD  . GLU E 2 178 ? 133.899 142.661 150.275 1.00 33.70  ? 180 GLU E CD  1 
ATOM   12213 O OE1 . GLU E 2 178 ? 133.815 142.109 149.159 1.00 33.70  ? 180 GLU E OE1 1 
ATOM   12214 O OE2 . GLU E 2 178 ? 133.178 143.623 150.614 1.00 33.70  ? 180 GLU E OE2 1 
ATOM   12215 N N   . SER E 2 179 ? 135.642 140.806 154.164 1.00 31.51  ? 181 SER E N   1 
ATOM   12216 C CA  . SER E 2 179 ? 134.773 140.923 155.322 1.00 31.51  ? 181 SER E CA  1 
ATOM   12217 C C   . SER E 2 179 ? 133.596 141.827 154.990 1.00 31.51  ? 181 SER E C   1 
ATOM   12218 O O   . SER E 2 179 ? 133.709 142.750 154.180 1.00 31.51  ? 181 SER E O   1 
ATOM   12219 C CB  . SER E 2 179 ? 135.532 141.486 156.520 1.00 31.51  ? 181 SER E CB  1 
ATOM   12220 O OG  . SER E 2 179 ? 135.396 142.894 156.582 1.00 31.51  ? 181 SER E OG  1 
ATOM   12221 N N   . PHE E 2 180 ? 132.456 141.556 155.618 1.00 31.03  ? 182 PHE E N   1 
ATOM   12222 C CA  . PHE E 2 180 ? 131.258 142.332 155.332 1.00 31.03  ? 182 PHE E CA  1 
ATOM   12223 C C   . PHE E 2 180 ? 130.740 143.113 156.528 1.00 31.03  ? 182 PHE E C   1 
ATOM   12224 O O   . PHE E 2 180 ? 130.540 144.328 156.426 1.00 31.03  ? 182 PHE E O   1 
ATOM   12225 C CB  . PHE E 2 180 ? 130.143 141.429 154.798 1.00 31.03  ? 182 PHE E CB  1 
ATOM   12226 C CG  . PHE E 2 180 ? 128.958 142.194 154.323 1.00 31.03  ? 182 PHE E CG  1 
ATOM   12227 C CD1 . PHE E 2 180 ? 128.963 142.789 153.078 1.00 31.03  ? 182 PHE E CD1 1 
ATOM   12228 C CD2 . PHE E 2 180 ? 127.855 142.357 155.133 1.00 31.03  ? 182 PHE E CD2 1 
ATOM   12229 C CE1 . PHE E 2 180 ? 127.885 143.514 152.644 1.00 31.03  ? 182 PHE E CE1 1 
ATOM   12230 C CE2 . PHE E 2 180 ? 126.776 143.080 154.701 1.00 31.03  ? 182 PHE E CE2 1 
ATOM   12231 C CZ  . PHE E 2 180 ? 126.798 143.668 153.460 1.00 31.03  ? 182 PHE E CZ  1 
ATOM   12232 N N   . GLY E 2 181 ? 130.513 142.456 157.661 1.00 32.32  ? 183 GLY E N   1 
ATOM   12233 C CA  . GLY E 2 181 ? 129.819 143.117 158.750 1.00 32.32  ? 183 GLY E CA  1 
ATOM   12234 C C   . GLY E 2 181 ? 130.639 144.139 159.505 1.00 32.32  ? 183 GLY E C   1 
ATOM   12235 O O   . GLY E 2 181 ? 130.080 144.850 160.346 1.00 32.32  ? 183 GLY E O   1 
ATOM   12236 N N   . TYR E 2 182 ? 131.936 144.239 159.227 1.00 36.14  ? 184 TYR E N   1 
ATOM   12237 C CA  . TYR E 2 182 ? 132.820 145.110 159.986 1.00 36.14  ? 184 TYR E CA  1 
ATOM   12238 C C   . TYR E 2 182 ? 133.567 146.042 159.047 1.00 36.14  ? 184 TYR E C   1 
ATOM   12239 O O   . TYR E 2 182 ? 134.124 145.601 158.038 1.00 36.14  ? 184 TYR E O   1 
ATOM   12240 C CB  . TYR E 2 182 ? 133.811 144.292 160.814 1.00 36.14  ? 184 TYR E CB  1 
ATOM   12241 C CG  . TYR E 2 182 ? 133.163 143.493 161.917 1.00 36.14  ? 184 TYR E CG  1 
ATOM   12242 C CD1 . TYR E 2 182 ? 132.680 142.217 161.679 1.00 36.14  ? 184 TYR E CD1 1 
ATOM   12243 C CD2 . TYR E 2 182 ? 133.035 144.014 163.195 1.00 36.14  ? 184 TYR E CD2 1 
ATOM   12244 C CE1 . TYR E 2 182 ? 132.089 141.482 162.680 1.00 36.14  ? 184 TYR E CE1 1 
ATOM   12245 C CE2 . TYR E 2 182 ? 132.445 143.285 164.203 1.00 36.14  ? 184 TYR E CE2 1 
ATOM   12246 C CZ  . TYR E 2 182 ? 131.974 142.020 163.939 1.00 36.14  ? 184 TYR E CZ  1 
ATOM   12247 O OH  . TYR E 2 182 ? 131.384 141.285 164.938 1.00 36.14  ? 184 TYR E OH  1 
ATOM   12248 N N   . THR E 2 183 ? 133.580 147.326 159.391 1.00 38.80  ? 185 THR E N   1 
ATOM   12249 C CA  . THR E 2 183 ? 134.344 148.319 158.657 1.00 38.80  ? 185 THR E CA  1 
ATOM   12250 C C   . THR E 2 183 ? 135.838 148.024 158.791 1.00 38.80  ? 185 THR E C   1 
ATOM   12251 O O   . THR E 2 183 ? 136.282 147.361 159.730 1.00 38.80  ? 185 THR E O   1 
ATOM   12252 C CB  . THR E 2 183 ? 134.013 149.719 159.183 1.00 38.80  ? 185 THR E CB  1 
ATOM   12253 O OG1 . THR E 2 183 ? 132.593 149.904 159.167 1.00 38.80  ? 185 THR E OG1 1 
ATOM   12254 C CG2 . THR E 2 183 ? 134.641 150.804 158.326 1.00 38.80  ? 185 THR E CG2 1 
ATOM   12255 N N   . THR E 2 184 ? 136.621 148.522 157.828 1.00 38.68  ? 186 THR E N   1 
ATOM   12256 C CA  . THR E 2 184 ? 138.062 148.295 157.855 1.00 38.68  ? 186 THR E CA  1 
ATOM   12257 C C   . THR E 2 184 ? 138.716 148.885 159.095 1.00 38.68  ? 186 THR E C   1 
ATOM   12258 O O   . THR E 2 184 ? 139.847 148.513 159.419 1.00 38.68  ? 186 THR E O   1 
ATOM   12259 C CB  . THR E 2 184 ? 138.722 148.877 156.606 1.00 38.68  ? 186 THR E CB  1 
ATOM   12260 O OG1 . THR E 2 184 ? 140.054 148.361 156.489 1.00 38.68  ? 186 THR E OG1 1 
ATOM   12261 C CG2 . THR E 2 184 ? 138.789 150.388 156.695 1.00 38.68  ? 186 THR E CG2 1 
ATOM   12262 N N   . ASP E 2 185 ? 138.040 149.800 159.790 1.00 44.06  ? 187 ASP E N   1 
ATOM   12263 C CA  . ASP E 2 185 ? 138.542 150.292 161.065 1.00 44.06  ? 187 ASP E CA  1 
ATOM   12264 C C   . ASP E 2 185 ? 138.387 149.276 162.187 1.00 44.06  ? 187 ASP E C   1 
ATOM   12265 O O   . ASP E 2 185 ? 138.885 149.521 163.289 1.00 44.06  ? 187 ASP E O   1 
ATOM   12266 C CB  . ASP E 2 185 ? 137.829 151.589 161.446 1.00 44.06  ? 187 ASP E CB  1 
ATOM   12267 C CG  . ASP E 2 185 ? 137.967 152.658 160.386 1.00 44.06  ? 187 ASP E CG  1 
ATOM   12268 O OD1 . ASP E 2 185 ? 138.933 152.591 159.598 1.00 44.06  ? 187 ASP E OD1 1 
ATOM   12269 O OD2 . ASP E 2 185 ? 137.110 153.564 160.340 1.00 44.06  ? 187 ASP E OD2 1 
ATOM   12270 N N   . ASP E 2 186 ? 137.704 148.162 161.943 1.00 40.83  ? 188 ASP E N   1 
ATOM   12271 C CA  . ASP E 2 186 ? 137.509 147.124 162.947 1.00 40.83  ? 188 ASP E CA  1 
ATOM   12272 C C   . ASP E 2 186 ? 138.130 145.791 162.567 1.00 40.83  ? 188 ASP E C   1 
ATOM   12273 O O   . ASP E 2 186 ? 138.706 145.122 163.427 1.00 40.83  ? 188 ASP E O   1 
ATOM   12274 C CB  . ASP E 2 186 ? 136.012 146.924 163.217 1.00 40.83  ? 188 ASP E CB  1 
ATOM   12275 C CG  . ASP E 2 186 ? 135.383 148.115 163.908 1.00 40.83  ? 188 ASP E CG  1 
ATOM   12276 O OD1 . ASP E 2 186 ? 136.114 149.076 164.219 1.00 40.83  ? 188 ASP E OD1 1 
ATOM   12277 O OD2 . ASP E 2 186 ? 134.157 148.089 164.143 1.00 40.83  ? 188 ASP E OD2 1 
ATOM   12278 N N   . LEU E 2 187 ? 138.031 145.383 161.305 1.00 36.38  ? 189 LEU E N   1 
ATOM   12279 C CA  . LEU E 2 187 ? 138.557 144.104 160.852 1.00 36.38  ? 189 LEU E CA  1 
ATOM   12280 C C   . LEU E 2 187 ? 139.433 144.316 159.628 1.00 36.38  ? 189 LEU E C   1 
ATOM   12281 O O   . LEU E 2 187 ? 139.099 145.113 158.748 1.00 36.38  ? 189 LEU E O   1 
ATOM   12282 C CB  . LEU E 2 187 ? 137.430 143.128 160.522 1.00 36.38  ? 189 LEU E CB  1 
ATOM   12283 C CG  . LEU E 2 187 ? 137.837 141.662 160.429 1.00 36.38  ? 189 LEU E CG  1 
ATOM   12284 C CD1 . LEU E 2 187 ? 138.263 141.158 161.790 1.00 36.38  ? 189 LEU E CD1 1 
ATOM   12285 C CD2 . LEU E 2 187 ? 136.695 140.828 159.889 1.00 36.38  ? 189 LEU E CD2 1 
ATOM   12286 N N   . ARG E 2 188 ? 140.553 143.599 159.575 1.00 33.33  ? 190 ARG E N   1 
ATOM   12287 C CA  . ARG E 2 188 ? 141.512 143.733 158.489 1.00 33.33  ? 190 ARG E CA  1 
ATOM   12288 C C   . ARG E 2 188 ? 142.071 142.363 158.137 1.00 33.33  ? 190 ARG E C   1 
ATOM   12289 O O   . ARG E 2 188 ? 142.392 141.572 159.027 1.00 33.33  ? 190 ARG E O   1 
ATOM   12290 C CB  . ARG E 2 188 ? 142.647 144.686 158.874 1.00 33.33  ? 190 ARG E CB  1 
ATOM   12291 C CG  . ARG E 2 188 ? 143.391 145.281 157.697 1.00 33.33  ? 190 ARG E CG  1 
ATOM   12292 C CD  . ARG E 2 188 ? 144.320 146.394 158.151 1.00 33.33  ? 190 ARG E CD  1 
ATOM   12293 N NE  . ARG E 2 188 ? 143.634 147.366 158.994 1.00 33.33  ? 190 ARG E NE  1 
ATOM   12294 C CZ  . ARG E 2 188 ? 144.243 148.327 159.677 1.00 33.33  ? 190 ARG E CZ  1 
ATOM   12295 N NH1 . ARG E 2 188 ? 145.558 148.466 159.653 1.00 33.33  ? 190 ARG E NH1 1 
ATOM   12296 N NH2 . ARG E 2 188 ? 143.513 149.170 160.401 1.00 33.33  ? 190 ARG E NH2 1 
ATOM   12297 N N   . PHE E 2 189 ? 142.195 142.090 156.841 1.00 30.35  ? 191 PHE E N   1 
ATOM   12298 C CA  . PHE E 2 189 ? 142.675 140.805 156.349 1.00 30.35  ? 191 PHE E CA  1 
ATOM   12299 C C   . PHE E 2 189 ? 144.090 140.954 155.812 1.00 30.35  ? 191 PHE E C   1 
ATOM   12300 O O   . PHE E 2 189 ? 144.374 141.880 155.046 1.00 30.35  ? 191 PHE E O   1 
ATOM   12301 C CB  . PHE E 2 189 ? 141.758 140.256 155.256 1.00 30.35  ? 191 PHE E CB  1 
ATOM   12302 C CG  . PHE E 2 189 ? 140.434 139.773 155.762 1.00 30.35  ? 191 PHE E CG  1 
ATOM   12303 C CD1 . PHE E 2 189 ? 140.249 139.497 157.101 1.00 30.35  ? 191 PHE E CD1 1 
ATOM   12304 C CD2 . PHE E 2 189 ? 139.376 139.588 154.895 1.00 30.35  ? 191 PHE E CD2 1 
ATOM   12305 C CE1 . PHE E 2 189 ? 139.034 139.051 157.566 1.00 30.35  ? 191 PHE E CE1 1 
ATOM   12306 C CE2 . PHE E 2 189 ? 138.160 139.143 155.355 1.00 30.35  ? 191 PHE E CE2 1 
ATOM   12307 C CZ  . PHE E 2 189 ? 137.988 138.874 156.692 1.00 30.35  ? 191 PHE E CZ  1 
ATOM   12308 N N   . ILE E 2 190 ? 144.973 140.044 156.214 1.00 31.40  ? 192 ILE E N   1 
ATOM   12309 C CA  . ILE E 2 190 ? 146.360 140.030 155.768 1.00 31.40  ? 192 ILE E CA  1 
ATOM   12310 C C   . ILE E 2 190 ? 146.731 138.598 155.416 1.00 31.40  ? 192 ILE E C   1 
ATOM   12311 O O   . ILE E 2 190 ? 146.425 137.672 156.173 1.00 31.40  ? 192 ILE E O   1 
ATOM   12312 C CB  . ILE E 2 190 ? 147.312 140.588 156.842 1.00 31.40  ? 192 ILE E CB  1 
ATOM   12313 C CG1 . ILE E 2 190 ? 147.038 142.072 157.084 1.00 31.40  ? 192 ILE E CG1 1 
ATOM   12314 C CG2 . ILE E 2 190 ? 148.759 140.381 156.435 1.00 31.40  ? 192 ILE E CG2 1 
ATOM   12315 C CD1 . ILE E 2 190 ? 147.796 142.651 158.259 1.00 31.40  ? 192 ILE E CD1 1 
ATOM   12316 N N   . TRP E 2 191 ? 147.384 138.416 154.272 1.00 32.40  ? 193 TRP E N   1 
ATOM   12317 C CA  . TRP E 2 191 ? 147.800 137.087 153.856 1.00 32.40  ? 193 TRP E CA  1 
ATOM   12318 C C   . TRP E 2 191 ? 148.925 136.569 154.745 1.00 32.40  ? 193 TRP E C   1 
ATOM   12319 O O   . TRP E 2 191 ? 149.671 137.332 155.362 1.00 32.40  ? 193 TRP E O   1 
ATOM   12320 C CB  . TRP E 2 191 ? 148.258 137.097 152.400 1.00 32.40  ? 193 TRP E CB  1 
ATOM   12321 C CG  . TRP E 2 191 ? 147.133 137.092 151.436 1.00 32.40  ? 193 TRP E CG  1 
ATOM   12322 C CD1 . TRP E 2 191 ? 146.758 138.108 150.614 1.00 32.40  ? 193 TRP E CD1 1 
ATOM   12323 C CD2 . TRP E 2 191 ? 146.220 136.020 151.193 1.00 32.40  ? 193 TRP E CD2 1 
ATOM   12324 N NE1 . TRP E 2 191 ? 145.670 137.735 149.869 1.00 32.40  ? 193 TRP E NE1 1 
ATOM   12325 C CE2 . TRP E 2 191 ? 145.320 136.455 150.207 1.00 32.40  ? 193 TRP E CE2 1 
ATOM   12326 C CE3 . TRP E 2 191 ? 146.079 134.733 151.712 1.00 32.40  ? 193 TRP E CE3 1 
ATOM   12327 C CZ2 . TRP E 2 191 ? 144.292 135.654 149.734 1.00 32.40  ? 193 TRP E CZ2 1 
ATOM   12328 C CZ3 . TRP E 2 191 ? 145.058 133.938 151.237 1.00 32.40  ? 193 TRP E CZ3 1 
ATOM   12329 C CH2 . TRP E 2 191 ? 144.180 134.399 150.257 1.00 32.40  ? 193 TRP E CH2 1 
ATOM   12330 N N   . GLN E 2 192 ? 149.038 135.246 154.807 1.00 40.40  ? 194 GLN E N   1 
ATOM   12331 C CA  . GLN E 2 192 ? 150.123 134.628 155.552 1.00 40.40  ? 194 GLN E CA  1 
ATOM   12332 C C   . GLN E 2 192 ? 151.451 134.901 154.858 1.00 40.40  ? 194 GLN E C   1 
ATOM   12333 O O   . GLN E 2 192 ? 151.520 134.991 153.630 1.00 40.40  ? 194 GLN E O   1 
ATOM   12334 C CB  . GLN E 2 192 ? 149.891 133.125 155.682 1.00 40.40  ? 194 GLN E CB  1 
ATOM   12335 C CG  . GLN E 2 192 ? 150.746 132.453 156.737 1.00 40.40  ? 194 GLN E CG  1 
ATOM   12336 C CD  . GLN E 2 192 ? 150.323 131.025 157.001 1.00 40.40  ? 194 GLN E CD  1 
ATOM   12337 O OE1 . GLN E 2 192 ? 149.142 130.743 157.201 1.00 40.40  ? 194 GLN E OE1 1 
ATOM   12338 N NE2 . GLN E 2 192 ? 151.286 130.113 157.002 1.00 40.40  ? 194 GLN E NE2 1 
ATOM   12339 N N   . SER E 2 193 ? 152.510 135.046 155.656 1.00 50.04  ? 195 SER E N   1 
ATOM   12340 C CA  . SER E 2 193 ? 153.810 135.404 155.099 1.00 50.04  ? 195 SER E CA  1 
ATOM   12341 C C   . SER E 2 193 ? 154.376 134.292 154.224 1.00 50.04  ? 195 SER E C   1 
ATOM   12342 O O   . SER E 2 193 ? 154.875 134.555 153.124 1.00 50.04  ? 195 SER E O   1 
ATOM   12343 C CB  . SER E 2 193 ? 154.783 135.745 156.226 1.00 50.04  ? 195 SER E CB  1 
ATOM   12344 O OG  . SER E 2 193 ? 154.857 134.690 157.168 1.00 50.04  ? 195 SER E OG  1 
ATOM   12345 N N   . GLY E 2 194 ? 154.305 133.046 154.687 1.00 47.81  ? 196 GLY E N   1 
ATOM   12346 C CA  . GLY E 2 194 ? 154.906 131.943 153.962 1.00 47.81  ? 196 GLY E CA  1 
ATOM   12347 C C   . GLY E 2 194 ? 153.916 130.940 153.406 1.00 47.81  ? 196 GLY E C   1 
ATOM   12348 O O   . GLY E 2 194 ? 153.205 130.275 154.165 1.00 47.81  ? 196 GLY E O   1 
ATOM   12349 N N   . ASP E 2 195 ? 153.874 130.819 152.077 1.00 41.18  ? 197 ASP E N   1 
ATOM   12350 C CA  . ASP E 2 195 ? 153.004 129.887 151.367 1.00 41.18  ? 197 ASP E CA  1 
ATOM   12351 C C   . ASP E 2 195 ? 151.553 130.050 151.802 1.00 41.18  ? 197 ASP E C   1 
ATOM   12352 O O   . ASP E 2 195 ? 151.012 129.178 152.493 1.00 41.18  ? 197 ASP E O   1 
ATOM   12353 C CB  . ASP E 2 195 ? 153.467 128.446 151.594 1.00 41.18  ? 197 ASP E CB  1 
ATOM   12354 C CG  . ASP E 2 195 ? 153.560 127.653 150.303 1.00 41.18  ? 197 ASP E CG  1 
ATOM   12355 O OD1 . ASP E 2 195 ? 153.260 128.218 149.231 1.00 41.18  ? 197 ASP E OD1 1 
ATOM   12356 O OD2 . ASP E 2 195 ? 153.936 126.464 150.361 1.00 41.18  ? 197 ASP E OD2 1 
ATOM   12357 N N   . PRO E 2 196 ? 150.890 131.147 151.426 1.00 37.05  ? 198 PRO E N   1 
ATOM   12358 C CA  . PRO E 2 196 ? 149.502 131.353 151.855 1.00 37.05  ? 198 PRO E CA  1 
ATOM   12359 C C   . PRO E 2 196 ? 148.471 130.613 151.022 1.00 37.05  ? 198 PRO E C   1 
ATOM   12360 O O   . PRO E 2 196 ? 147.298 130.584 151.416 1.00 37.05  ? 198 PRO E O   1 
ATOM   12361 C CB  . PRO E 2 196 ? 149.325 132.867 151.722 1.00 37.05  ? 198 PRO E CB  1 
ATOM   12362 C CG  . PRO E 2 196 ? 150.231 133.236 150.619 1.00 37.05  ? 198 PRO E CG  1 
ATOM   12363 C CD  . PRO E 2 196 ? 151.397 132.286 150.644 1.00 37.05  ? 198 PRO E CD  1 
ATOM   12364 N N   . VAL E 2 197 ? 148.849 130.037 149.885 1.00 33.00  ? 199 VAL E N   1 
ATOM   12365 C CA  . VAL E 2 197 ? 147.961 129.185 149.103 1.00 33.00  ? 199 VAL E CA  1 
ATOM   12366 C C   . VAL E 2 197 ? 148.731 127.930 148.725 1.00 33.00  ? 199 VAL E C   1 
ATOM   12367 O O   . VAL E 2 197 ? 149.775 128.015 148.070 1.00 33.00  ? 199 VAL E O   1 
ATOM   12368 C CB  . VAL E 2 197 ? 147.431 129.892 147.847 1.00 33.00  ? 199 VAL E CB  1 
ATOM   12369 C CG1 . VAL E 2 197 ? 146.706 128.903 146.959 1.00 33.00  ? 199 VAL E CG1 1 
ATOM   12370 C CG2 . VAL E 2 197 ? 146.508 131.025 148.233 1.00 33.00  ? 199 VAL E CG2 1 
ATOM   12371 N N   . GLN E 2 198 ? 148.220 126.771 149.132 1.00 37.02  ? 200 GLN E N   1 
ATOM   12372 C CA  . GLN E 2 198 ? 148.862 125.492 148.864 1.00 37.02  ? 200 GLN E CA  1 
ATOM   12373 C C   . GLN E 2 198 ? 147.893 124.579 148.132 1.00 37.02  ? 200 GLN E C   1 
ATOM   12374 O O   . GLN E 2 198 ? 146.748 124.412 148.563 1.00 37.02  ? 200 GLN E O   1 
ATOM   12375 C CB  . GLN E 2 198 ? 149.328 124.829 150.159 1.00 37.02  ? 200 GLN E CB  1 
ATOM   12376 C CG  . GLN E 2 198 ? 150.092 125.754 151.080 1.00 37.02  ? 200 GLN E CG  1 
ATOM   12377 C CD  . GLN E 2 198 ? 149.261 126.211 152.256 1.00 37.02  ? 200 GLN E CD  1 
ATOM   12378 O OE1 . GLN E 2 198 ? 148.169 125.700 152.492 1.00 37.02  ? 200 GLN E OE1 1 
ATOM   12379 N NE2 . GLN E 2 198 ? 149.774 127.182 153.001 1.00 37.02  ? 200 GLN E NE2 1 
ATOM   12380 N N   . LEU E 2 199 ? 148.354 123.989 147.034 1.00 45.63  ? 201 LEU E N   1 
ATOM   12381 C CA  . LEU E 2 199 ? 147.580 123.018 146.273 1.00 45.63  ? 201 LEU E CA  1 
ATOM   12382 C C   . LEU E 2 199 ? 148.434 121.781 146.049 1.00 45.63  ? 201 LEU E C   1 
ATOM   12383 O O   . LEU E 2 199 ? 149.643 121.887 145.824 1.00 45.63  ? 201 LEU E O   1 
ATOM   12384 C CB  . LEU E 2 199 ? 147.110 123.593 144.932 1.00 45.63  ? 201 LEU E CB  1 
ATOM   12385 C CG  . LEU E 2 199 ? 148.154 124.268 144.043 1.00 45.63  ? 201 LEU E CG  1 
ATOM   12386 C CD1 . LEU E 2 199 ? 147.808 124.060 142.583 1.00 45.63  ? 201 LEU E CD1 1 
ATOM   12387 C CD2 . LEU E 2 199 ? 148.245 125.752 144.354 1.00 45.63  ? 201 LEU E CD2 1 
ATOM   12388 N N   . GLU E 2 200 ? 147.807 120.611 146.111 1.00 52.68  ? 202 GLU E N   1 
ATOM   12389 C CA  . GLU E 2 200 ? 148.524 119.337 146.094 1.00 52.68  ? 202 GLU E CA  1 
ATOM   12390 C C   . GLU E 2 200 ? 148.287 118.634 144.760 1.00 52.68  ? 202 GLU E C   1 
ATOM   12391 O O   . GLU E 2 200 ? 147.403 117.785 144.641 1.00 52.68  ? 202 GLU E O   1 
ATOM   12392 C CB  . GLU E 2 200 ? 148.092 118.459 147.263 1.00 52.68  ? 202 GLU E CB  1 
ATOM   12393 C CG  . GLU E 2 200 ? 149.222 117.639 147.864 1.00 52.68  ? 202 GLU E CG  1 
ATOM   12394 C CD  . GLU E 2 200 ? 149.851 116.693 146.861 1.00 52.68  ? 202 GLU E CD  1 
ATOM   12395 O OE1 . GLU E 2 200 ? 149.105 115.923 146.221 1.00 52.68  ? 202 GLU E OE1 1 
ATOM   12396 O OE2 . GLU E 2 200 ? 151.090 116.723 146.710 1.00 52.68  ? 202 GLU E OE2 1 
ATOM   12397 N N   . LYS E 2 201 ? 149.102 118.986 143.766 1.00 52.61  ? 203 LYS E N   1 
ATOM   12398 C CA  . LYS E 2 201 ? 149.180 118.284 142.485 1.00 52.61  ? 203 LYS E CA  1 
ATOM   12399 C C   . LYS E 2 201 ? 147.796 118.054 141.876 1.00 52.61  ? 203 LYS E C   1 
ATOM   12400 O O   . LYS E 2 201 ? 147.381 116.926 141.607 1.00 52.61  ? 203 LYS E O   1 
ATOM   12401 C CB  . LYS E 2 201 ? 149.932 116.961 142.644 1.00 52.61  ? 203 LYS E CB  1 
ATOM   12402 N N   . ILE E 2 202 ? 147.081 119.154 141.658 1.00 51.53  ? 204 ILE E N   1 
ATOM   12403 C CA  . ILE E 2 202 ? 145.742 119.116 141.085 1.00 51.53  ? 204 ILE E CA  1 
ATOM   12404 C C   . ILE E 2 202 ? 145.838 119.459 139.606 1.00 51.53  ? 204 ILE E C   1 
ATOM   12405 O O   . ILE E 2 202 ? 146.527 120.412 139.221 1.00 51.53  ? 204 ILE E O   1 
ATOM   12406 C CB  . ILE E 2 202 ? 144.786 120.069 141.824 1.00 51.53  ? 204 ILE E CB  1 
ATOM   12407 C CG1 . ILE E 2 202 ? 143.383 119.978 141.225 1.00 51.53  ? 204 ILE E CG1 1 
ATOM   12408 C CG2 . ILE E 2 202 ? 145.303 121.499 141.802 1.00 51.53  ? 204 ILE E CG2 1 
ATOM   12409 C CD1 . ILE E 2 202 ? 142.812 118.575 141.229 1.00 51.53  ? 204 ILE E CD1 1 
ATOM   12410 N N   . ALA E 2 203 ? 145.171 118.664 138.772 1.00 56.70  ? 205 ALA E N   1 
ATOM   12411 C CA  . ALA E 2 203 ? 145.211 118.833 137.325 1.00 56.70  ? 205 ALA E CA  1 
ATOM   12412 C C   . ALA E 2 203 ? 143.791 118.947 136.796 1.00 56.70  ? 205 ALA E C   1 
ATOM   12413 O O   . ALA E 2 203 ? 143.003 118.005 136.922 1.00 56.70  ? 205 ALA E O   1 
ATOM   12414 C CB  . ALA E 2 203 ? 145.942 117.668 136.653 1.00 56.70  ? 205 ALA E CB  1 
ATOM   12415 N N   . LEU E 2 204 ? 143.472 120.094 136.207 1.00 51.38  ? 206 LEU E N   1 
ATOM   12416 C CA  . LEU E 2 204 ? 142.184 120.267 135.561 1.00 51.38  ? 206 LEU E CA  1 
ATOM   12417 C C   . LEU E 2 204 ? 142.115 119.406 134.299 1.00 51.38  ? 206 LEU E C   1 
ATOM   12418 O O   . LEU E 2 204 ? 143.147 119.064 133.716 1.00 51.38  ? 206 LEU E O   1 
ATOM   12419 C CB  . LEU E 2 204 ? 141.952 121.736 135.209 1.00 51.38  ? 206 LEU E CB  1 
ATOM   12420 C CG  . LEU E 2 204 ? 141.969 122.773 136.334 1.00 51.38  ? 206 LEU E CG  1 
ATOM   12421 C CD1 . LEU E 2 204 ? 143.381 123.218 136.686 1.00 51.38  ? 206 LEU E CD1 1 
ATOM   12422 C CD2 . LEU E 2 204 ? 141.113 123.967 135.952 1.00 51.38  ? 206 LEU E CD2 1 
ATOM   12423 N N   . PRO E 2 205 ? 140.909 119.028 133.865 1.00 50.91  ? 207 PRO E N   1 
ATOM   12424 C CA  . PRO E 2 205 ? 140.805 118.154 132.684 1.00 50.91  ? 207 PRO E CA  1 
ATOM   12425 C C   . PRO E 2 205 ? 141.395 118.753 131.422 1.00 50.91  ? 207 PRO E C   1 
ATOM   12426 O O   . PRO E 2 205 ? 141.939 118.010 130.596 1.00 50.91  ? 207 PRO E O   1 
ATOM   12427 C CB  . PRO E 2 205 ? 139.292 117.935 132.548 1.00 50.91  ? 207 PRO E CB  1 
ATOM   12428 C CG  . PRO E 2 205 ? 138.676 119.103 133.238 1.00 50.91  ? 207 PRO E CG  1 
ATOM   12429 C CD  . PRO E 2 205 ? 139.584 119.392 134.393 1.00 50.91  ? 207 PRO E CD  1 
ATOM   12430 N N   . GLN E 2 206 ? 141.308 120.072 131.240 1.00 51.84  ? 208 GLN E N   1 
ATOM   12431 C CA  . GLN E 2 206 ? 141.762 120.706 130.009 1.00 51.84  ? 208 GLN E CA  1 
ATOM   12432 C C   . GLN E 2 206 ? 142.680 121.899 130.248 1.00 51.84  ? 208 GLN E C   1 
ATOM   12433 O O   . GLN E 2 206 ? 143.039 122.585 129.286 1.00 51.84  ? 208 GLN E O   1 
ATOM   12434 C CB  . GLN E 2 206 ? 140.563 121.156 129.167 1.00 51.84  ? 208 GLN E CB  1 
ATOM   12435 C CG  . GLN E 2 206 ? 139.343 121.526 129.989 1.00 51.84  ? 208 GLN E CG  1 
ATOM   12436 C CD  . GLN E 2 206 ? 138.055 121.386 129.210 1.00 51.84  ? 208 GLN E CD  1 
ATOM   12437 O OE1 . GLN E 2 206 ? 138.044 120.860 128.099 1.00 51.84  ? 208 GLN E OE1 1 
ATOM   12438 N NE2 . GLN E 2 206 ? 136.957 121.857 129.789 1.00 51.84  ? 208 GLN E NE2 1 
ATOM   12439 N N   . PHE E 2 207 ? 143.071 122.165 131.489 1.00 46.00  ? 209 PHE E N   1 
ATOM   12440 C CA  . PHE E 2 207 ? 143.837 123.358 131.815 1.00 46.00  ? 209 PHE E CA  1 
ATOM   12441 C C   . PHE E 2 207 ? 145.116 122.969 132.542 1.00 46.00  ? 209 PHE E C   1 
ATOM   12442 O O   . PHE E 2 207 ? 145.350 121.802 132.861 1.00 46.00  ? 209 PHE E O   1 
ATOM   12443 C CB  . PHE E 2 207 ? 143.015 124.327 132.671 1.00 46.00  ? 209 PHE E CB  1 
ATOM   12444 C CG  . PHE E 2 207 ? 142.006 125.117 131.894 1.00 46.00  ? 209 PHE E CG  1 
ATOM   12445 C CD1 . PHE E 2 207 ? 140.822 124.535 131.483 1.00 46.00  ? 209 PHE E CD1 1 
ATOM   12446 C CD2 . PHE E 2 207 ? 142.237 126.445 131.584 1.00 46.00  ? 209 PHE E CD2 1 
ATOM   12447 C CE1 . PHE E 2 207 ? 139.891 125.261 130.772 1.00 46.00  ? 209 PHE E CE1 1 
ATOM   12448 C CE2 . PHE E 2 207 ? 141.309 127.175 130.875 1.00 46.00  ? 209 PHE E CE2 1 
ATOM   12449 C CZ  . PHE E 2 207 ? 140.134 126.583 130.468 1.00 46.00  ? 209 PHE E CZ  1 
ATOM   12450 N N   . ASP E 2 208 ? 145.949 123.975 132.801 1.00 52.83  ? 210 ASP E N   1 
ATOM   12451 C CA  . ASP E 2 208 ? 147.220 123.785 133.499 1.00 52.83  ? 210 ASP E CA  1 
ATOM   12452 C C   . ASP E 2 208 ? 147.427 125.008 134.387 1.00 52.83  ? 210 ASP E C   1 
ATOM   12453 O O   . ASP E 2 208 ? 147.898 126.048 133.919 1.00 52.83  ? 210 ASP E O   1 
ATOM   12454 C CB  . ASP E 2 208 ? 148.367 123.603 132.511 1.00 52.83  ? 210 ASP E CB  1 
ATOM   12455 C CG  . ASP E 2 208 ? 149.675 123.215 133.184 1.00 52.83  ? 210 ASP E CG  1 
ATOM   12456 O OD1 . ASP E 2 208 ? 149.905 123.599 134.349 1.00 52.83  ? 210 ASP E OD1 1 
ATOM   12457 O OD2 . ASP E 2 208 ? 150.483 122.517 132.536 1.00 52.83  ? 210 ASP E OD2 1 
ATOM   12458 N N   . ILE E 2 209 ? 147.081 124.878 135.662 1.00 48.64  ? 211 ILE E N   1 
ATOM   12459 C CA  . ILE E 2 209 ? 147.217 125.979 136.608 1.00 48.64  ? 211 ILE E CA  1 
ATOM   12460 C C   . ILE E 2 209 ? 148.687 126.151 136.965 1.00 48.64  ? 211 ILE E C   1 
ATOM   12461 O O   . ILE E 2 209 ? 149.375 125.182 137.308 1.00 48.64  ? 211 ILE E O   1 
ATOM   12462 C CB  . ILE E 2 209 ? 146.366 125.728 137.862 1.00 48.64  ? 211 ILE E CB  1 
ATOM   12463 C CG1 . ILE E 2 209 ? 146.778 126.674 138.989 1.00 48.64  ? 211 ILE E CG1 1 
ATOM   12464 C CG2 . ILE E 2 209 ? 146.485 124.282 138.307 1.00 48.64  ? 211 ILE E CG2 1 
ATOM   12465 C CD1 . ILE E 2 209 ? 145.941 126.533 140.238 1.00 48.64  ? 211 ILE E CD1 1 
ATOM   12466 N N   . LYS E 2 210 ? 149.175 127.386 136.882 1.00 52.73  ? 212 LYS E N   1 
ATOM   12467 C CA  . LYS E 2 210 ? 150.559 127.689 137.229 1.00 52.73  ? 212 LYS E CA  1 
ATOM   12468 C C   . LYS E 2 210 ? 150.668 127.837 138.741 1.00 52.73  ? 212 LYS E C   1 
ATOM   12469 O O   . LYS E 2 210 ? 150.123 128.781 139.321 1.00 52.73  ? 212 LYS E O   1 
ATOM   12470 C CB  . LYS E 2 210 ? 151.024 128.956 136.518 1.00 52.73  ? 212 LYS E CB  1 
ATOM   12471 C CG  . LYS E 2 210 ? 150.542 129.076 135.087 1.00 52.73  ? 212 LYS E CG  1 
ATOM   12472 C CD  . LYS E 2 210 ? 151.509 128.397 134.134 1.00 52.73  ? 212 LYS E CD  1 
ATOM   12473 C CE  . LYS E 2 210 ? 151.411 128.982 132.738 1.00 52.73  ? 212 LYS E CE  1 
ATOM   12474 N NZ  . LYS E 2 210 ? 151.793 130.421 132.716 1.00 52.73  ? 212 LYS E NZ  1 
ATOM   12475 N N   . LYS E 2 211 ? 151.370 126.901 139.381 1.00 56.42  ? 213 LYS E N   1 
ATOM   12476 C CA  . LYS E 2 211 ? 151.522 126.955 140.831 1.00 56.42  ? 213 LYS E CA  1 
ATOM   12477 C C   . LYS E 2 211 ? 152.348 128.161 141.259 1.00 56.42  ? 213 LYS E C   1 
ATOM   12478 O O   . LYS E 2 211 ? 152.024 128.822 142.252 1.00 56.42  ? 213 LYS E O   1 
ATOM   12479 C CB  . LYS E 2 211 ? 152.157 125.663 141.339 1.00 56.42  ? 213 LYS E CB  1 
ATOM   12480 N N   . GLU E 2 212 ? 153.423 128.460 140.527 1.00 61.12  ? 214 GLU E N   1 
ATOM   12481 C CA  . GLU E 2 212 ? 154.292 129.567 140.912 1.00 61.12  ? 214 GLU E CA  1 
ATOM   12482 C C   . GLU E 2 212 ? 153.652 130.915 140.600 1.00 61.12  ? 214 GLU E C   1 
ATOM   12483 O O   . GLU E 2 212 ? 153.731 131.847 141.408 1.00 61.12  ? 214 GLU E O   1 
ATOM   12484 C CB  . GLU E 2 212 ? 155.644 129.438 140.209 1.00 61.12  ? 214 GLU E CB  1 
ATOM   12485 C CG  . GLU E 2 212 ? 156.395 130.750 140.046 1.00 61.12  ? 214 GLU E CG  1 
ATOM   12486 C CD  . GLU E 2 212 ? 157.900 130.564 140.025 1.00 61.12  ? 214 GLU E CD  1 
ATOM   12487 O OE1 . GLU E 2 212 ? 158.395 129.815 139.156 1.00 61.12  ? 214 GLU E OE1 1 
ATOM   12488 O OE2 . GLU E 2 212 ? 158.588 131.167 140.875 1.00 61.12  ? 214 GLU E OE2 1 
ATOM   12489 N N   . ASP E 2 213 ? 153.008 131.036 139.439 1.00 53.81  ? 215 ASP E N   1 
ATOM   12490 C CA  . ASP E 2 213 ? 152.457 132.315 138.989 1.00 53.81  ? 215 ASP E CA  1 
ATOM   12491 C C   . ASP E 2 213 ? 151.030 132.459 139.511 1.00 53.81  ? 215 ASP E C   1 
ATOM   12492 O O   . ASP E 2 213 ? 150.044 132.246 138.803 1.00 53.81  ? 215 ASP E O   1 
ATOM   12493 C CB  . ASP E 2 213 ? 152.516 132.417 137.471 1.00 53.81  ? 215 ASP E CB  1 
ATOM   12494 C CG  . ASP E 2 213 ? 152.360 133.841 136.978 1.00 53.81  ? 215 ASP E CG  1 
ATOM   12495 O OD1 . ASP E 2 213 ? 153.357 134.592 137.006 1.00 53.81  ? 215 ASP E OD1 1 
ATOM   12496 O OD2 . ASP E 2 213 ? 151.241 134.209 136.566 1.00 53.81  ? 215 ASP E OD2 1 
ATOM   12497 N N   . ILE E 2 214 ? 150.928 132.835 140.784 1.00 41.02  ? 216 ILE E N   1 
ATOM   12498 C CA  . ILE E 2 214 ? 149.651 133.110 141.436 1.00 41.02  ? 216 ILE E CA  1 
ATOM   12499 C C   . ILE E 2 214 ? 149.757 134.518 142.007 1.00 41.02  ? 216 ILE E C   1 
ATOM   12500 O O   . ILE E 2 214 ? 150.327 134.717 143.085 1.00 41.02  ? 216 ILE E O   1 
ATOM   12501 C CB  . ILE E 2 214 ? 149.316 132.091 142.529 1.00 41.02  ? 216 ILE E CB  1 
ATOM   12502 C CG1 . ILE E 2 214 ? 149.180 130.692 141.930 1.00 41.02  ? 216 ILE E CG1 1 
ATOM   12503 C CG2 . ILE E 2 214 ? 148.035 132.478 143.237 1.00 41.02  ? 216 ILE E CG2 1 
ATOM   12504 C CD1 . ILE E 2 214 ? 148.541 129.689 142.863 1.00 41.02  ? 216 ILE E CD1 1 
ATOM   12505 N N   . GLU E 2 215 ? 149.219 135.499 141.289 1.00 39.72  ? 217 GLU E N   1 
ATOM   12506 C CA  . GLU E 2 215 ? 149.337 136.886 141.714 1.00 39.72  ? 217 GLU E CA  1 
ATOM   12507 C C   . GLU E 2 215 ? 148.441 137.168 142.913 1.00 39.72  ? 217 GLU E C   1 
ATOM   12508 O O   . GLU E 2 215 ? 147.322 136.659 143.008 1.00 39.72  ? 217 GLU E O   1 
ATOM   12509 C CB  . GLU E 2 215 ? 148.986 137.827 140.561 1.00 39.72  ? 217 GLU E CB  1 
ATOM   12510 C CG  . GLU E 2 215 ? 149.102 139.302 140.907 1.00 39.72  ? 217 GLU E CG  1 
ATOM   12511 C CD  . GLU E 2 215 ? 150.090 140.033 140.023 1.00 39.72  ? 217 GLU E CD  1 
ATOM   12512 O OE1 . GLU E 2 215 ? 150.747 139.373 139.191 1.00 39.72  ? 217 GLU E OE1 1 
ATOM   12513 O OE2 . GLU E 2 215 ? 150.213 141.268 140.162 1.00 39.72  ? 217 GLU E OE2 1 
ATOM   12514 N N   . TYR E 2 216 ? 148.944 137.987 143.828 1.00 38.42  ? 218 TYR E N   1 
ATOM   12515 C CA  . TYR E 2 216 ? 148.247 138.398 145.035 1.00 38.42  ? 218 TYR E CA  1 
ATOM   12516 C C   . TYR E 2 216 ? 147.900 139.882 144.952 1.00 38.42  ? 218 TYR E C   1 
ATOM   12517 O O   . TYR E 2 216 ? 148.098 140.536 143.923 1.00 38.42  ? 218 TYR E O   1 
ATOM   12518 C CB  . TYR E 2 216 ? 149.099 138.087 146.263 1.00 38.42  ? 218 TYR E CB  1 
ATOM   12519 C CG  . TYR E 2 216 ? 149.234 136.616 146.551 1.00 38.42  ? 218 TYR E CG  1 
ATOM   12520 C CD1 . TYR E 2 216 ? 148.359 135.698 145.995 1.00 38.42  ? 218 TYR E CD1 1 
ATOM   12521 C CD2 . TYR E 2 216 ? 150.248 136.143 147.365 1.00 38.42  ? 218 TYR E CD2 1 
ATOM   12522 C CE1 . TYR E 2 216 ? 148.483 134.354 146.254 1.00 38.42  ? 218 TYR E CE1 1 
ATOM   12523 C CE2 . TYR E 2 216 ? 150.382 134.803 147.624 1.00 38.42  ? 218 TYR E CE2 1 
ATOM   12524 C CZ  . TYR E 2 216 ? 149.497 133.911 147.069 1.00 38.42  ? 218 TYR E CZ  1 
ATOM   12525 O OH  . TYR E 2 216 ? 149.627 132.567 147.329 1.00 38.42  ? 218 TYR E OH  1 
ATOM   12526 N N   . GLY E 2 217 ? 147.374 140.411 146.041 1.00 40.04  ? 219 GLY E N   1 
ATOM   12527 C CA  . GLY E 2 217 ? 147.012 141.813 146.141 1.00 40.04  ? 219 GLY E CA  1 
ATOM   12528 C C   . GLY E 2 217 ? 145.692 141.950 146.870 1.00 40.04  ? 219 GLY E C   1 
ATOM   12529 O O   . GLY E 2 217 ? 144.922 141.001 147.007 1.00 40.04  ? 219 GLY E O   1 
ATOM   12530 N N   . ASN E 2 218 ? 145.429 143.159 147.361 1.00 45.75  ? 220 ASN E N   1 
ATOM   12531 C CA  . ASN E 2 218 ? 144.202 143.428 148.095 1.00 45.75  ? 220 ASN E CA  1 
ATOM   12532 C C   . ASN E 2 218 ? 143.556 144.707 147.586 1.00 45.75  ? 220 ASN E C   1 
ATOM   12533 O O   . ASN E 2 218 ? 144.233 145.618 147.104 1.00 45.75  ? 220 ASN E O   1 
ATOM   12534 C CB  . ASN E 2 218 ? 144.458 143.487 149.616 1.00 45.75  ? 220 ASN E CB  1 
ATOM   12535 C CG  . ASN E 2 218 ? 145.086 144.791 150.078 1.00 45.75  ? 220 ASN E CG  1 
ATOM   12536 O OD1 . ASN E 2 218 ? 145.807 145.460 149.340 1.00 45.75  ? 220 ASN E OD1 1 
ATOM   12537 N ND2 . ASN E 2 218 ? 144.814 145.144 151.331 1.00 45.75  ? 220 ASN E ND2 1 
ATOM   12538 N N   . CYS E 2 219 ? 142.229 144.756 147.688 1.00 44.81  ? 221 CYS E N   1 
ATOM   12539 C CA  . CYS E 2 219 ? 141.422 145.801 147.070 1.00 44.81  ? 221 CYS E CA  1 
ATOM   12540 C C   . CYS E 2 219 ? 140.875 146.814 148.063 1.00 44.81  ? 221 CYS E C   1 
ATOM   12541 O O   . CYS E 2 219 ? 140.956 148.021 147.814 1.00 44.81  ? 221 CYS E O   1 
ATOM   12542 C CB  . CYS E 2 219 ? 140.263 145.165 146.286 1.00 44.81  ? 221 CYS E CB  1 
ATOM   12543 S SG  . CYS E 2 219 ? 139.599 143.642 147.008 1.00 44.81  ? 221 CYS E SG  1 
ATOM   12544 N N   . THR E 2 220 ? 140.320 146.358 149.185 1.00 34.55  ? 222 THR E N   1 
ATOM   12545 C CA  . THR E 2 220 ? 139.633 147.221 150.146 1.00 34.55  ? 222 THR E CA  1 
ATOM   12546 C C   . THR E 2 220 ? 138.565 148.057 149.442 1.00 34.55  ? 222 THR E C   1 
ATOM   12547 O O   . THR E 2 220 ? 138.613 149.287 149.411 1.00 34.55  ? 222 THR E O   1 
ATOM   12548 C CB  . THR E 2 220 ? 140.617 148.116 150.903 1.00 34.55  ? 222 THR E CB  1 
ATOM   12549 O OG1 . THR E 2 220 ? 141.065 149.169 150.042 1.00 34.55  ? 222 THR E OG1 1 
ATOM   12550 C CG2 . THR E 2 220 ? 141.810 147.310 151.377 1.00 34.55  ? 222 THR E CG2 1 
ATOM   12551 N N   . LYS E 2 221 ? 137.596 147.353 148.862 1.00 33.06  ? 223 LYS E N   1 
ATOM   12552 C CA  . LYS E 2 221 ? 136.550 148.017 148.099 1.00 33.06  ? 223 LYS E CA  1 
ATOM   12553 C C   . LYS E 2 221 ? 135.736 148.936 148.997 1.00 33.06  ? 223 LYS E C   1 
ATOM   12554 O O   . LYS E 2 221 ? 135.510 148.645 150.174 1.00 33.06  ? 223 LYS E O   1 
ATOM   12555 C CB  . LYS E 2 221 ? 135.642 146.985 147.431 1.00 33.06  ? 223 LYS E CB  1 
ATOM   12556 C CG  . LYS E 2 221 ? 135.244 145.827 148.324 1.00 33.06  ? 223 LYS E CG  1 
ATOM   12557 C CD  . LYS E 2 221 ? 135.221 144.519 147.547 1.00 33.06  ? 223 LYS E CD  1 
ATOM   12558 C CE  . LYS E 2 221 ? 134.463 144.661 146.238 1.00 33.06  ? 223 LYS E CE  1 
ATOM   12559 N NZ  . LYS E 2 221 ? 134.511 143.412 145.430 1.00 33.06  ? 223 LYS E NZ  1 
ATOM   12560 N N   . TYR E 2 222 ? 135.303 150.060 148.432 1.00 40.50  ? 224 TYR E N   1 
ATOM   12561 C CA  . TYR E 2 222 ? 134.621 151.112 149.173 1.00 40.50  ? 224 TYR E CA  1 
ATOM   12562 C C   . TYR E 2 222 ? 133.240 151.324 148.573 1.00 40.50  ? 224 TYR E C   1 
ATOM   12563 O O   . TYR E 2 222 ? 133.120 151.718 147.408 1.00 40.50  ? 224 TYR E O   1 
ATOM   12564 C CB  . TYR E 2 222 ? 135.438 152.406 149.136 1.00 40.50  ? 224 TYR E CB  1 
ATOM   12565 C CG  . TYR E 2 222 ? 134.650 153.667 149.401 1.00 40.50  ? 224 TYR E CG  1 
ATOM   12566 C CD1 . TYR E 2 222 ? 134.333 154.049 150.695 1.00 40.50  ? 224 TYR E CD1 1 
ATOM   12567 C CD2 . TYR E 2 222 ? 134.246 154.489 148.358 1.00 40.50  ? 224 TYR E CD2 1 
ATOM   12568 C CE1 . TYR E 2 222 ? 133.622 155.206 150.943 1.00 40.50  ? 224 TYR E CE1 1 
ATOM   12569 C CE2 . TYR E 2 222 ? 133.535 155.647 148.597 1.00 40.50  ? 224 TYR E CE2 1 
ATOM   12570 C CZ  . TYR E 2 222 ? 133.226 156.001 149.891 1.00 40.50  ? 224 TYR E CZ  1 
ATOM   12571 O OH  . TYR E 2 222 ? 132.517 157.153 150.136 1.00 40.50  ? 224 TYR E OH  1 
ATOM   12572 N N   . TYR E 2 223 ? 132.205 151.067 149.366 1.00 36.76  ? 225 TYR E N   1 
ATOM   12573 C CA  . TYR E 2 223 ? 130.827 151.289 148.956 1.00 36.76  ? 225 TYR E CA  1 
ATOM   12574 C C   . TYR E 2 223 ? 130.335 152.608 149.531 1.00 36.76  ? 225 TYR E C   1 
ATOM   12575 O O   . TYR E 2 223 ? 130.585 152.918 150.700 1.00 36.76  ? 225 TYR E O   1 
ATOM   12576 C CB  . TYR E 2 223 ? 129.921 150.151 149.422 1.00 36.76  ? 225 TYR E CB  1 
ATOM   12577 C CG  . TYR E 2 223 ? 130.423 148.777 149.062 1.00 36.76  ? 225 TYR E CG  1 
ATOM   12578 C CD1 . TYR E 2 223 ? 130.465 148.357 147.742 1.00 36.76  ? 225 TYR E CD1 1 
ATOM   12579 C CD2 . TYR E 2 223 ? 130.847 147.896 150.042 1.00 36.76  ? 225 TYR E CD2 1 
ATOM   12580 C CE1 . TYR E 2 223 ? 130.921 147.100 147.411 1.00 36.76  ? 225 TYR E CE1 1 
ATOM   12581 C CE2 . TYR E 2 223 ? 131.304 146.638 149.721 1.00 36.76  ? 225 TYR E CE2 1 
ATOM   12582 C CZ  . TYR E 2 223 ? 131.339 146.245 148.405 1.00 36.76  ? 225 TYR E CZ  1 
ATOM   12583 O OH  . TYR E 2 223 ? 131.796 144.990 148.085 1.00 36.76  ? 225 TYR E OH  1 
ATOM   12584 N N   . LYS E 2 224 ? 129.637 153.383 148.704 1.00 39.43  ? 226 LYS E N   1 
ATOM   12585 C CA  . LYS E 2 224 ? 129.212 154.715 149.111 1.00 39.43  ? 226 LYS E CA  1 
ATOM   12586 C C   . LYS E 2 224 ? 128.266 154.642 150.302 1.00 39.43  ? 226 LYS E C   1 
ATOM   12587 O O   . LYS E 2 224 ? 127.292 153.884 150.294 1.00 39.43  ? 226 LYS E O   1 
ATOM   12588 C CB  . LYS E 2 224 ? 128.536 155.431 147.942 1.00 39.43  ? 226 LYS E CB  1 
ATOM   12589 N N   . GLY E 2 225 ? 128.557 155.439 151.326 1.00 41.17  ? 227 GLY E N   1 
ATOM   12590 C CA  . GLY E 2 225 ? 127.714 155.513 152.500 1.00 41.17  ? 227 GLY E CA  1 
ATOM   12591 C C   . GLY E 2 225 ? 127.853 154.372 153.480 1.00 41.17  ? 227 GLY E C   1 
ATOM   12592 O O   . GLY E 2 225 ? 127.053 154.286 154.418 1.00 41.17  ? 227 GLY E O   1 
ATOM   12593 N N   . THR E 2 226 ? 128.840 153.490 153.302 1.00 40.02  ? 228 THR E N   1 
ATOM   12594 C CA  . THR E 2 226 ? 128.996 152.365 154.215 1.00 40.02  ? 228 THR E CA  1 
ATOM   12595 C C   . THR E 2 226 ? 130.454 152.096 154.577 1.00 40.02  ? 228 THR E C   1 
ATOM   12596 O O   . THR E 2 226 ? 130.773 150.996 155.042 1.00 40.02  ? 228 THR E O   1 
ATOM   12597 C CB  . THR E 2 226 ? 128.377 151.098 153.622 1.00 40.02  ? 228 THR E CB  1 
ATOM   12598 O OG1 . THR E 2 226 ? 128.562 151.098 152.202 1.00 40.02  ? 228 THR E OG1 1 
ATOM   12599 C CG2 . THR E 2 226 ? 126.893 151.037 153.932 1.00 40.02  ? 228 THR E CG2 1 
ATOM   12600 N N   . GLY E 2 227 ? 131.346 153.061 154.378 1.00 43.61  ? 229 GLY E N   1 
ATOM   12601 C CA  . GLY E 2 227 ? 132.724 152.888 154.786 1.00 43.61  ? 229 GLY E CA  1 
ATOM   12602 C C   . GLY E 2 227 ? 133.502 151.955 153.871 1.00 43.61  ? 229 GLY E C   1 
ATOM   12603 O O   . GLY E 2 227 ? 133.050 151.546 152.802 1.00 43.61  ? 229 GLY E O   1 
ATOM   12604 N N   . TYR E 2 228 ? 134.705 151.617 154.327 1.00 42.57  ? 230 TYR E N   1 
ATOM   12605 C CA  . TYR E 2 228 ? 135.621 150.763 153.584 1.00 42.57  ? 230 TYR E CA  1 
ATOM   12606 C C   . TYR E 2 228 ? 135.585 149.350 154.150 1.00 42.57  ? 230 TYR E C   1 
ATOM   12607 O O   . TYR E 2 228 ? 135.702 149.161 155.364 1.00 42.57  ? 230 TYR E O   1 
ATOM   12608 C CB  . TYR E 2 228 ? 137.049 151.307 153.644 1.00 42.57  ? 230 TYR E CB  1 
ATOM   12609 C CG  . TYR E 2 228 ? 137.201 152.729 153.159 1.00 42.57  ? 230 TYR E CG  1 
ATOM   12610 C CD1 . TYR E 2 228 ? 137.006 153.801 154.018 1.00 42.57  ? 230 TYR E CD1 1 
ATOM   12611 C CD2 . TYR E 2 228 ? 137.554 152.999 151.845 1.00 42.57  ? 230 TYR E CD2 1 
ATOM   12612 C CE1 . TYR E 2 228 ? 137.148 155.103 153.580 1.00 42.57  ? 230 TYR E CE1 1 
ATOM   12613 C CE2 . TYR E 2 228 ? 137.698 154.298 151.397 1.00 42.57  ? 230 TYR E CE2 1 
ATOM   12614 C CZ  . TYR E 2 228 ? 137.494 155.346 152.269 1.00 42.57  ? 230 TYR E CZ  1 
ATOM   12615 O OH  . TYR E 2 228 ? 137.637 156.641 151.829 1.00 42.57  ? 230 TYR E OH  1 
ATOM   12616 N N   . TYR E 2 229 ? 135.429 148.366 153.272 1.00 34.83  ? 231 TYR E N   1 
ATOM   12617 C CA  . TYR E 2 229 ? 135.467 146.958 153.644 1.00 34.83  ? 231 TYR E CA  1 
ATOM   12618 C C   . TYR E 2 229 ? 136.724 146.341 153.052 1.00 34.83  ? 231 TYR E C   1 
ATOM   12619 O O   . TYR E 2 229 ? 136.948 146.431 151.840 1.00 34.83  ? 231 TYR E O   1 
ATOM   12620 C CB  . TYR E 2 229 ? 134.227 146.217 153.146 1.00 34.83  ? 231 TYR E CB  1 
ATOM   12621 C CG  . TYR E 2 229 ? 132.919 146.715 153.714 1.00 34.83  ? 231 TYR E CG  1 
ATOM   12622 C CD1 . TYR E 2 229 ? 132.884 147.506 154.850 1.00 34.83  ? 231 TYR E CD1 1 
ATOM   12623 C CD2 . TYR E 2 229 ? 131.715 146.384 153.112 1.00 34.83  ? 231 TYR E CD2 1 
ATOM   12624 C CE1 . TYR E 2 229 ? 131.691 147.958 155.366 1.00 34.83  ? 231 TYR E CE1 1 
ATOM   12625 C CE2 . TYR E 2 229 ? 130.518 146.831 153.620 1.00 34.83  ? 231 TYR E CE2 1 
ATOM   12626 C CZ  . TYR E 2 229 ? 130.511 147.617 154.747 1.00 34.83  ? 231 TYR E CZ  1 
ATOM   12627 O OH  . TYR E 2 229 ? 129.316 148.065 155.257 1.00 34.83  ? 231 TYR E OH  1 
ATOM   12628 N N   . THR E 2 230 ? 137.539 145.718 153.898 1.00 32.94  ? 232 THR E N   1 
ATOM   12629 C CA  . THR E 2 230 ? 138.787 145.131 153.432 1.00 32.94  ? 232 THR E CA  1 
ATOM   12630 C C   . THR E 2 230 ? 138.524 143.867 152.623 1.00 32.94  ? 232 THR E C   1 
ATOM   12631 O O   . THR E 2 230 ? 137.575 143.125 152.880 1.00 32.94  ? 232 THR E O   1 
ATOM   12632 C CB  . THR E 2 230 ? 139.697 144.806 154.610 1.00 32.94  ? 232 THR E CB  1 
ATOM   12633 O OG1 . THR E 2 230 ? 140.795 144.009 154.154 1.00 32.94  ? 232 THR E OG1 1 
ATOM   12634 C CG2 . THR E 2 230 ? 138.934 144.039 155.666 1.00 32.94  ? 232 THR E CG2 1 
ATOM   12635 N N   . CYS E 2 231 ? 139.381 143.625 151.633 1.00 31.74  ? 233 CYS E N   1 
ATOM   12636 C CA  . CYS E 2 231 ? 139.235 142.452 150.778 1.00 31.74  ? 233 CYS E CA  1 
ATOM   12637 C C   . CYS E 2 231 ? 140.600 142.023 150.265 1.00 31.74  ? 233 CYS E C   1 
ATOM   12638 O O   . CYS E 2 231 ? 141.253 142.773 149.536 1.00 31.74  ? 233 CYS E O   1 
ATOM   12639 C CB  . CYS E 2 231 ? 138.291 142.734 149.606 1.00 31.74  ? 233 CYS E CB  1 
ATOM   12640 S SG  . CYS E 2 231 ? 138.631 144.253 148.686 1.00 31.74  ? 233 CYS E SG  1 
ATOM   12641 N N   . VAL E 2 232 ? 141.028 140.823 150.650 1.00 29.39  ? 234 VAL E N   1 
ATOM   12642 C CA  . VAL E 2 232 ? 142.206 140.199 150.061 1.00 29.39  ? 234 VAL E CA  1 
ATOM   12643 C C   . VAL E 2 232 ? 141.780 139.533 148.762 1.00 29.39  ? 234 VAL E C   1 
ATOM   12644 O O   . VAL E 2 232 ? 140.583 139.391 148.493 1.00 29.39  ? 234 VAL E O   1 
ATOM   12645 C CB  . VAL E 2 232 ? 142.854 139.195 151.027 1.00 29.39  ? 234 VAL E CB  1 
ATOM   12646 C CG1 . VAL E 2 232 ? 143.690 139.930 152.053 1.00 29.39  ? 234 VAL E CG1 1 
ATOM   12647 C CG2 . VAL E 2 232 ? 141.789 138.374 151.713 1.00 29.39  ? 234 VAL E CG2 1 
ATOM   12648 N N   . GLU E 2 233 ? 142.744 139.123 147.943 1.00 34.06  ? 235 GLU E N   1 
ATOM   12649 C CA  . GLU E 2 233 ? 142.435 138.665 146.597 1.00 34.06  ? 235 GLU E CA  1 
ATOM   12650 C C   . GLU E 2 233 ? 143.470 137.652 146.135 1.00 34.06  ? 235 GLU E C   1 
ATOM   12651 O O   . GLU E 2 233 ? 144.652 137.767 146.465 1.00 34.06  ? 235 GLU E O   1 
ATOM   12652 C CB  . GLU E 2 233 ? 142.388 139.852 145.631 1.00 34.06  ? 235 GLU E CB  1 
ATOM   12653 C CG  . GLU E 2 233 ? 141.737 139.584 144.295 1.00 34.06  ? 235 GLU E CG  1 
ATOM   12654 C CD  . GLU E 2 233 ? 141.732 140.821 143.418 1.00 34.06  ? 235 GLU E CD  1 
ATOM   12655 O OE1 . GLU E 2 233 ? 141.732 141.941 143.971 1.00 34.06  ? 235 GLU E OE1 1 
ATOM   12656 O OE2 . GLU E 2 233 ? 141.745 140.678 142.180 1.00 34.06  ? 235 GLU E OE2 1 
ATOM   12657 N N   . VAL E 2 234 ? 143.014 136.664 145.369 1.00 30.29  ? 236 VAL E N   1 
ATOM   12658 C CA  . VAL E 2 234 ? 143.876 135.684 144.720 1.00 30.29  ? 236 VAL E CA  1 
ATOM   12659 C C   . VAL E 2 234 ? 143.538 135.671 143.239 1.00 30.29  ? 236 VAL E C   1 
ATOM   12660 O O   . VAL E 2 234 ? 142.361 135.700 142.865 1.00 30.29  ? 236 VAL E O   1 
ATOM   12661 C CB  . VAL E 2 234 ? 143.708 134.273 145.320 1.00 30.29  ? 236 VAL E CB  1 
ATOM   12662 C CG1 . VAL E 2 234 ? 144.422 133.243 144.469 1.00 30.29  ? 236 VAL E CG1 1 
ATOM   12663 C CG2 . VAL E 2 234 ? 144.247 134.233 146.719 1.00 30.29  ? 236 VAL E CG2 1 
ATOM   12664 N N   . ILE E 2 235 ? 144.564 135.639 142.395 1.00 34.34  ? 237 ILE E N   1 
ATOM   12665 C CA  . ILE E 2 235 ? 144.390 135.579 140.950 1.00 34.34  ? 237 ILE E CA  1 
ATOM   12666 C C   . ILE E 2 235 ? 145.080 134.322 140.442 1.00 34.34  ? 237 ILE E C   1 
ATOM   12667 O O   . ILE E 2 235 ? 146.282 134.136 140.663 1.00 34.34  ? 237 ILE E O   1 
ATOM   12668 C CB  . ILE E 2 235 ? 144.949 136.829 140.257 1.00 34.34  ? 237 ILE E CB  1 
ATOM   12669 C CG1 . ILE E 2 235 ? 144.232 138.080 140.763 1.00 34.34  ? 237 ILE E CG1 1 
ATOM   12670 C CG2 . ILE E 2 235 ? 144.798 136.707 138.756 1.00 34.34  ? 237 ILE E CG2 1 
ATOM   12671 C CD1 . ILE E 2 235 ? 144.632 139.347 140.042 1.00 34.34  ? 237 ILE E CD1 1 
ATOM   12672 N N   . PHE E 2 236 ? 144.325 133.466 139.762 1.00 35.03  ? 238 PHE E N   1 
ATOM   12673 C CA  . PHE E 2 236 ? 144.856 132.250 139.164 1.00 35.03  ? 238 PHE E CA  1 
ATOM   12674 C C   . PHE E 2 236 ? 145.071 132.460 137.673 1.00 35.03  ? 238 PHE E C   1 
ATOM   12675 O O   . PHE E 2 236 ? 144.252 133.093 137.002 1.00 35.03  ? 238 PHE E O   1 
ATOM   12676 C CB  . PHE E 2 236 ? 143.913 131.067 139.381 1.00 35.03  ? 238 PHE E CB  1 
ATOM   12677 C CG  . PHE E 2 236 ? 143.781 130.650 140.812 1.00 35.03  ? 238 PHE E CG  1 
ATOM   12678 C CD1 . PHE E 2 236 ? 144.823 130.015 141.459 1.00 35.03  ? 238 PHE E CD1 1 
ATOM   12679 C CD2 . PHE E 2 236 ? 142.612 130.884 141.508 1.00 35.03  ? 238 PHE E CD2 1 
ATOM   12680 C CE1 . PHE E 2 236 ? 144.702 129.629 142.775 1.00 35.03  ? 238 PHE E CE1 1 
ATOM   12681 C CE2 . PHE E 2 236 ? 142.487 130.500 142.823 1.00 35.03  ? 238 PHE E CE2 1 
ATOM   12682 C CZ  . PHE E 2 236 ? 143.532 129.872 143.458 1.00 35.03  ? 238 PHE E CZ  1 
ATOM   12683 N N   . THR E 2 237 ? 146.171 131.928 137.159 1.00 43.13  ? 239 THR E N   1 
ATOM   12684 C CA  . THR E 2 237 ? 146.492 131.999 135.736 1.00 43.13  ? 239 THR E CA  1 
ATOM   12685 C C   . THR E 2 237 ? 146.285 130.612 135.140 1.00 43.13  ? 239 THR E C   1 
ATOM   12686 O O   . THR E 2 237 ? 147.138 129.732 135.281 1.00 43.13  ? 239 THR E O   1 
ATOM   12687 C CB  . THR E 2 237 ? 147.918 132.492 135.521 1.00 43.13  ? 239 THR E CB  1 
ATOM   12688 O OG1 . THR E 2 237 ? 148.813 131.737 136.346 1.00 43.13  ? 239 THR E OG1 1 
ATOM   12689 C CG2 . THR E 2 237 ? 148.029 133.964 135.877 1.00 43.13  ? 239 THR E CG2 1 
ATOM   12690 N N   . LEU E 2 238 ? 145.151 130.420 134.473 1.00 42.29  ? 240 LEU E N   1 
ATOM   12691 C CA  . LEU E 2 238 ? 144.799 129.142 133.869 1.00 42.29  ? 240 LEU E CA  1 
ATOM   12692 C C   . LEU E 2 238 ? 145.123 129.184 132.382 1.00 42.29  ? 240 LEU E C   1 
ATOM   12693 O O   . LEU E 2 238 ? 144.582 130.019 131.649 1.00 42.29  ? 240 LEU E O   1 
ATOM   12694 C CB  . LEU E 2 238 ? 143.320 128.829 134.086 1.00 42.29  ? 240 LEU E CB  1 
ATOM   12695 C CG  . LEU E 2 238 ? 142.890 128.568 135.528 1.00 42.29  ? 240 LEU E CG  1 
ATOM   12696 C CD1 . LEU E 2 238 ? 141.379 128.495 135.633 1.00 42.29  ? 240 LEU E CD1 1 
ATOM   12697 C CD2 . LEU E 2 238 ? 143.522 127.290 136.036 1.00 42.29  ? 240 LEU E CD2 1 
ATOM   12698 N N   . ARG E 2 239 ? 145.995 128.284 131.939 1.00 52.53  ? 241 ARG E N   1 
ATOM   12699 C CA  . ARG E 2 239 ? 146.375 128.177 130.537 1.00 52.53  ? 241 ARG E CA  1 
ATOM   12700 C C   . ARG E 2 239 ? 145.621 127.012 129.910 1.00 52.53  ? 241 ARG E C   1 
ATOM   12701 O O   . ARG E 2 239 ? 145.719 125.877 130.388 1.00 52.53  ? 241 ARG E O   1 
ATOM   12702 C CB  . ARG E 2 239 ? 147.883 127.979 130.391 1.00 52.53  ? 241 ARG E CB  1 
ATOM   12703 C CG  . ARG E 2 239 ? 148.677 129.270 130.378 1.00 52.53  ? 241 ARG E CG  1 
ATOM   12704 C CD  . ARG E 2 239 ? 149.745 129.246 129.301 1.00 52.53  ? 241 ARG E CD  1 
ATOM   12705 N NE  . ARG E 2 239 ? 149.170 129.084 127.971 1.00 52.53  ? 241 ARG E NE  1 
ATOM   12706 C CZ  . ARG E 2 239 ? 149.874 129.048 126.848 1.00 52.53  ? 241 ARG E CZ  1 
ATOM   12707 N NH1 . ARG E 2 239 ? 151.192 129.162 126.855 1.00 52.53  ? 241 ARG E NH1 1 
ATOM   12708 N NH2 . ARG E 2 239 ? 149.240 128.895 125.689 1.00 52.53  ? 241 ARG E NH2 1 
ATOM   12709 N N   . ARG E 2 240 ? 144.875 127.291 128.847 1.00 48.22  ? 242 ARG E N   1 
ATOM   12710 C CA  . ARG E 2 240 ? 144.070 126.267 128.198 1.00 48.22  ? 242 ARG E CA  1 
ATOM   12711 C C   . ARG E 2 240 ? 144.937 125.406 127.290 1.00 48.22  ? 242 ARG E C   1 
ATOM   12712 O O   . ARG E 2 240 ? 145.736 125.925 126.506 1.00 48.22  ? 242 ARG E O   1 
ATOM   12713 C CB  . ARG E 2 240 ? 142.940 126.907 127.396 1.00 48.22  ? 242 ARG E CB  1 
ATOM   12714 C CG  . ARG E 2 240 ? 142.073 125.908 126.655 1.00 48.22  ? 242 ARG E CG  1 
ATOM   12715 C CD  . ARG E 2 240 ? 141.133 126.605 125.694 1.00 48.22  ? 242 ARG E CD  1 
ATOM   12716 N NE  . ARG E 2 240 ? 140.267 127.557 126.376 1.00 48.22  ? 242 ARG E NE  1 
ATOM   12717 C CZ  . ARG E 2 240 ? 139.029 127.293 126.766 1.00 48.22  ? 242 ARG E CZ  1 
ATOM   12718 N NH1 . ARG E 2 240 ? 138.476 126.110 126.556 1.00 48.22  ? 242 ARG E NH1 1 
ATOM   12719 N NH2 . ARG E 2 240 ? 138.327 128.238 127.383 1.00 48.22  ? 242 ARG E NH2 1 
ATOM   12720 N N   . GLN E 2 241 ? 144.779 124.091 127.401 1.00 53.33  ? 243 GLN E N   1 
ATOM   12721 C CA  . GLN E 2 241 ? 145.475 123.167 126.519 1.00 53.33  ? 243 GLN E CA  1 
ATOM   12722 C C   . GLN E 2 241 ? 144.766 123.100 125.173 1.00 53.33  ? 243 GLN E C   1 
ATOM   12723 O O   . GLN E 2 241 ? 143.535 123.045 125.106 1.00 53.33  ? 243 GLN E O   1 
ATOM   12724 C CB  . GLN E 2 241 ? 145.546 121.775 127.146 1.00 53.33  ? 243 GLN E CB  1 
ATOM   12725 C CG  . GLN E 2 241 ? 146.178 121.743 128.529 1.00 53.33  ? 243 GLN E CG  1 
ATOM   12726 C CD  . GLN E 2 241 ? 147.695 121.736 128.489 1.00 53.33  ? 243 GLN E CD  1 
ATOM   12727 O OE1 . GLN E 2 241 ? 148.314 122.505 127.754 1.00 53.33  ? 243 GLN E OE1 1 
ATOM   12728 N NE2 . GLN E 2 241 ? 148.301 120.861 129.283 1.00 53.33  ? 243 GLN E NE2 1 
ATOM   12729 N N   . VAL E 2 242 ? 145.554 123.101 124.096 1.00 56.06  ? 244 VAL E N   1 
ATOM   12730 C CA  . VAL E 2 242 ? 145.013 123.178 122.745 1.00 56.06  ? 244 VAL E CA  1 
ATOM   12731 C C   . VAL E 2 242 ? 144.988 121.827 122.045 1.00 56.06  ? 244 VAL E C   1 
ATOM   12732 O O   . VAL E 2 242 ? 144.592 121.753 120.874 1.00 56.06  ? 244 VAL E O   1 
ATOM   12733 C CB  . VAL E 2 242 ? 145.802 124.211 121.913 1.00 56.06  ? 244 VAL E CB  1 
ATOM   12734 C CG1 . VAL E 2 242 ? 147.053 123.585 121.309 1.00 56.06  ? 244 VAL E CG1 1 
ATOM   12735 C CG2 . VAL E 2 242 ? 144.919 124.836 120.840 1.00 56.06  ? 244 VAL E CG2 1 
ATOM   12736 N N   . GLY E 2 243 ? 145.378 120.751 122.730 1.00 61.60  ? 245 GLY E N   1 
ATOM   12737 C CA  . GLY E 2 243 ? 145.471 119.458 122.070 1.00 61.60  ? 245 GLY E CA  1 
ATOM   12738 C C   . GLY E 2 243 ? 144.137 118.946 121.561 1.00 61.60  ? 245 GLY E C   1 
ATOM   12739 O O   . GLY E 2 243 ? 144.040 118.459 120.430 1.00 61.60  ? 245 GLY E O   1 
ATOM   12740 N N   . PHE E 2 244 ? 143.091 119.048 122.384 1.00 65.01  ? 246 PHE E N   1 
ATOM   12741 C CA  . PHE E 2 244 ? 141.785 118.530 121.989 1.00 65.01  ? 246 PHE E CA  1 
ATOM   12742 C C   . PHE E 2 244 ? 141.237 119.268 120.775 1.00 65.01  ? 246 PHE E C   1 
ATOM   12743 O O   . PHE E 2 244 ? 140.682 118.649 119.861 1.00 65.01  ? 246 PHE E O   1 
ATOM   12744 C CB  . PHE E 2 244 ? 140.804 118.625 123.156 1.00 65.01  ? 246 PHE E CB  1 
ATOM   12745 C CG  . PHE E 2 244 ? 139.368 118.441 122.759 1.00 65.01  ? 246 PHE E CG  1 
ATOM   12746 C CD1 . PHE E 2 244 ? 138.902 117.204 122.352 1.00 65.01  ? 246 PHE E CD1 1 
ATOM   12747 C CD2 . PHE E 2 244 ? 138.484 119.503 122.798 1.00 65.01  ? 246 PHE E CD2 1 
ATOM   12748 C CE1 . PHE E 2 244 ? 137.582 117.031 121.989 1.00 65.01  ? 246 PHE E CE1 1 
ATOM   12749 C CE2 . PHE E 2 244 ? 137.163 119.336 122.437 1.00 65.01  ? 246 PHE E CE2 1 
ATOM   12750 C CZ  . PHE E 2 244 ? 136.712 118.099 122.031 1.00 65.01  ? 246 PHE E CZ  1 
ATOM   12751 N N   . TYR E 2 245 ? 141.381 120.593 120.748 1.00 64.21  ? 247 TYR E N   1 
ATOM   12752 C CA  . TYR E 2 245 ? 140.862 121.360 119.623 1.00 64.21  ? 247 TYR E CA  1 
ATOM   12753 C C   . TYR E 2 245 ? 141.728 121.195 118.382 1.00 64.21  ? 247 TYR E C   1 
ATOM   12754 O O   . TYR E 2 245 ? 141.216 121.263 117.259 1.00 64.21  ? 247 TYR E O   1 
ATOM   12755 C CB  . TYR E 2 245 ? 140.740 122.832 120.007 1.00 64.21  ? 247 TYR E CB  1 
ATOM   12756 C CG  . TYR E 2 245 ? 139.560 123.107 120.907 1.00 64.21  ? 247 TYR E CG  1 
ATOM   12757 C CD1 . TYR E 2 245 ? 138.279 123.221 120.387 1.00 64.21  ? 247 TYR E CD1 1 
ATOM   12758 C CD2 . TYR E 2 245 ? 139.725 123.235 122.278 1.00 64.21  ? 247 TYR E CD2 1 
ATOM   12759 C CE1 . TYR E 2 245 ? 137.197 123.465 121.206 1.00 64.21  ? 247 TYR E CE1 1 
ATOM   12760 C CE2 . TYR E 2 245 ? 138.650 123.479 123.105 1.00 64.21  ? 247 TYR E CE2 1 
ATOM   12761 C CZ  . TYR E 2 245 ? 137.389 123.592 122.565 1.00 64.21  ? 247 TYR E CZ  1 
ATOM   12762 O OH  . TYR E 2 245 ? 136.314 123.836 123.387 1.00 64.21  ? 247 TYR E OH  1 
ATOM   12763 N N   . MET E 2 246 ? 143.035 120.985 118.557 1.00 68.74  ? 248 MET E N   1 
ATOM   12764 C CA  . MET E 2 246 ? 143.896 120.727 117.408 1.00 68.74  ? 248 MET E CA  1 
ATOM   12765 C C   . MET E 2 246 ? 143.581 119.378 116.778 1.00 68.74  ? 248 MET E C   1 
ATOM   12766 O O   . MET E 2 246 ? 143.587 119.244 115.549 1.00 68.74  ? 248 MET E O   1 
ATOM   12767 C CB  . MET E 2 246 ? 145.365 120.798 117.820 1.00 68.74  ? 248 MET E CB  1 
ATOM   12768 C CG  . MET E 2 246 ? 145.983 122.175 117.666 1.00 68.74  ? 248 MET E CG  1 
ATOM   12769 S SD  . MET E 2 246 ? 147.786 122.152 117.660 1.00 68.74  ? 248 MET E SD  1 
ATOM   12770 C CE  . MET E 2 246 ? 148.116 120.408 117.419 1.00 68.74  ? 248 MET E CE  1 
ATOM   12771 N N   . MET E 2 247 ? 143.307 118.369 117.598 1.00 67.23  ? 249 MET E N   1 
ATOM   12772 C CA  . MET E 2 247 ? 142.928 117.056 117.096 1.00 67.23  ? 249 MET E CA  1 
ATOM   12773 C C   . MET E 2 247 ? 141.432 116.930 116.846 1.00 67.23  ? 249 MET E C   1 
ATOM   12774 O O   . MET E 2 247 ? 140.983 115.877 116.383 1.00 67.23  ? 249 MET E O   1 
ATOM   12775 C CB  . MET E 2 247 ? 143.378 115.966 118.074 1.00 67.23  ? 249 MET E CB  1 
ATOM   12776 C CG  . MET E 2 247 ? 144.888 115.820 118.194 1.00 67.23  ? 249 MET E CG  1 
ATOM   12777 S SD  . MET E 2 247 ? 145.633 114.978 116.783 1.00 67.23  ? 249 MET E SD  1 
ATOM   12778 C CE  . MET E 2 247 ? 147.364 115.018 117.241 1.00 67.23  ? 249 MET E CE  1 
ATOM   12779 N N   . GLY E 2 248 ? 140.654 117.966 117.144 1.00 66.47  ? 250 GLY E N   1 
ATOM   12780 C CA  . GLY E 2 248 ? 139.216 117.891 116.991 1.00 66.47  ? 250 GLY E CA  1 
ATOM   12781 C C   . GLY E 2 248 ? 138.670 118.526 115.729 1.00 66.47  ? 250 GLY E C   1 
ATOM   12782 O O   . GLY E 2 248 ? 137.846 117.924 115.036 1.00 66.47  ? 250 GLY E O   1 
ATOM   12783 N N   . VAL E 2 249 ? 139.111 119.747 115.420 1.00 65.60  ? 251 VAL E N   1 
ATOM   12784 C CA  . VAL E 2 249 ? 138.567 120.520 114.313 1.00 65.60  ? 251 VAL E CA  1 
ATOM   12785 C C   . VAL E 2 249 ? 139.619 120.835 113.257 1.00 65.60  ? 251 VAL E C   1 
ATOM   12786 O O   . VAL E 2 249 ? 139.320 120.823 112.054 1.00 65.60  ? 251 VAL E O   1 
ATOM   12787 C CB  . VAL E 2 249 ? 137.893 121.814 114.821 1.00 65.60  ? 251 VAL E CB  1 
ATOM   12788 C CG1 . VAL E 2 249 ? 136.988 121.487 115.980 1.00 65.60  ? 251 VAL E CG1 1 
ATOM   12789 C CG2 . VAL E 2 249 ? 138.919 122.849 115.252 1.00 65.60  ? 251 VAL E CG2 1 
ATOM   12790 N N   . TYR E 2 250 ? 140.853 121.122 113.676 1.00 63.47  ? 252 TYR E N   1 
ATOM   12791 C CA  . TYR E 2 250 ? 141.869 121.589 112.739 1.00 63.47  ? 252 TYR E CA  1 
ATOM   12792 C C   . TYR E 2 250 ? 142.194 120.521 111.703 1.00 63.47  ? 252 TYR E C   1 
ATOM   12793 O O   . TYR E 2 250 ? 142.268 120.806 110.502 1.00 63.47  ? 252 TYR E O   1 
ATOM   12794 C CB  . TYR E 2 250 ? 143.123 122.011 113.503 1.00 63.47  ? 252 TYR E CB  1 
ATOM   12795 C CG  . TYR E 2 250 ? 142.998 123.362 114.170 1.00 63.47  ? 252 TYR E CG  1 
ATOM   12796 C CD1 . TYR E 2 250 ? 142.074 124.294 113.721 1.00 63.47  ? 252 TYR E CD1 1 
ATOM   12797 C CD2 . TYR E 2 250 ? 143.804 123.705 115.246 1.00 63.47  ? 252 TYR E CD2 1 
ATOM   12798 C CE1 . TYR E 2 250 ? 141.956 125.529 114.325 1.00 63.47  ? 252 TYR E CE1 1 
ATOM   12799 C CE2 . TYR E 2 250 ? 143.692 124.940 115.856 1.00 63.47  ? 252 TYR E CE2 1 
ATOM   12800 C CZ  . TYR E 2 250 ? 142.767 125.847 115.391 1.00 63.47  ? 252 TYR E CZ  1 
ATOM   12801 O OH  . TYR E 2 250 ? 142.650 127.078 115.993 1.00 63.47  ? 252 TYR E OH  1 
ATOM   12802 N N   . ALA E 2 251 ? 142.394 119.283 112.151 1.00 61.79  ? 253 ALA E N   1 
ATOM   12803 C CA  . ALA E 2 251 ? 142.678 118.200 111.212 1.00 61.79  ? 253 ALA E CA  1 
ATOM   12804 C C   . ALA E 2 251 ? 141.520 117.928 110.260 1.00 61.79  ? 253 ALA E C   1 
ATOM   12805 O O   . ALA E 2 251 ? 141.769 117.803 109.047 1.00 61.79  ? 253 ALA E O   1 
ATOM   12806 C CB  . ALA E 2 251 ? 143.092 116.942 111.984 1.00 61.79  ? 253 ALA E CB  1 
ATOM   12807 N N   . PRO E 2 252 ? 140.264 117.794 110.710 1.00 64.71  ? 254 PRO E N   1 
ATOM   12808 C CA  . PRO E 2 252 ? 139.174 117.630 109.733 1.00 64.71  ? 254 PRO E CA  1 
ATOM   12809 C C   . PRO E 2 252 ? 139.050 118.790 108.759 1.00 64.71  ? 254 PRO E C   1 
ATOM   12810 O O   . PRO E 2 252 ? 138.776 118.564 107.573 1.00 64.71  ? 254 PRO E O   1 
ATOM   12811 C CB  . PRO E 2 252 ? 137.930 117.492 110.621 1.00 64.71  ? 254 PRO E CB  1 
ATOM   12812 C CG  . PRO E 2 252 ? 138.451 116.930 111.886 1.00 64.71  ? 254 PRO E CG  1 
ATOM   12813 C CD  . PRO E 2 252 ? 139.772 117.607 112.088 1.00 64.71  ? 254 PRO E CD  1 
ATOM   12814 N N   . THR E 2 253 ? 139.250 120.029 109.215 1.00 65.75  ? 255 THR E N   1 
ATOM   12815 C CA  . THR E 2 253 ? 139.168 121.156 108.291 1.00 65.75  ? 255 THR E CA  1 
ATOM   12816 C C   . THR E 2 253 ? 140.284 121.103 107.253 1.00 65.75  ? 255 THR E C   1 
ATOM   12817 O O   . THR E 2 253 ? 140.042 121.320 106.056 1.00 65.75  ? 255 THR E O   1 
ATOM   12818 C CB  . THR E 2 253 ? 139.211 122.471 109.062 1.00 65.75  ? 255 THR E CB  1 
ATOM   12819 O OG1 . THR E 2 253 ? 140.137 122.355 110.148 1.00 65.75  ? 255 THR E OG1 1 
ATOM   12820 C CG2 . THR E 2 253 ? 137.837 122.799 109.615 1.00 65.75  ? 255 THR E CG2 1 
ATOM   12821 N N   . LEU E 2 254 ? 141.511 120.805 107.692 1.00 64.65  ? 256 LEU E N   1 
ATOM   12822 C CA  . LEU E 2 254 ? 142.617 120.657 106.754 1.00 64.65  ? 256 LEU E CA  1 
ATOM   12823 C C   . LEU E 2 254 ? 142.328 119.560 105.743 1.00 64.65  ? 256 LEU E C   1 
ATOM   12824 O O   . LEU E 2 254 ? 142.608 119.713 104.549 1.00 64.65  ? 256 LEU E O   1 
ATOM   12825 C CB  . LEU E 2 254 ? 143.911 120.354 107.508 1.00 64.65  ? 256 LEU E CB  1 
ATOM   12826 C CG  . LEU E 2 254 ? 144.965 121.457 107.561 1.00 64.65  ? 256 LEU E CG  1 
ATOM   12827 C CD1 . LEU E 2 254 ? 145.465 121.772 106.164 1.00 64.65  ? 256 LEU E CD1 1 
ATOM   12828 C CD2 . LEU E 2 254 ? 144.404 122.696 108.221 1.00 64.65  ? 256 LEU E CD2 1 
ATOM   12829 N N   . LEU E 2 255 ? 141.760 118.445 106.204 1.00 65.72  ? 257 LEU E N   1 
ATOM   12830 C CA  . LEU E 2 255 ? 141.443 117.353 105.295 1.00 65.72  ? 257 LEU E CA  1 
ATOM   12831 C C   . LEU E 2 255 ? 140.351 117.743 104.308 1.00 65.72  ? 257 LEU E C   1 
ATOM   12832 O O   . LEU E 2 255 ? 140.385 117.312 103.153 1.00 65.72  ? 257 LEU E O   1 
ATOM   12833 C CB  . LEU E 2 255 ? 141.041 116.114 106.089 1.00 65.72  ? 257 LEU E CB  1 
ATOM   12834 C CG  . LEU E 2 255 ? 142.232 115.411 106.744 1.00 65.72  ? 257 LEU E CG  1 
ATOM   12835 C CD1 . LEU E 2 255 ? 141.803 114.116 107.402 1.00 65.72  ? 257 LEU E CD1 1 
ATOM   12836 C CD2 . LEU E 2 255 ? 143.333 115.160 105.727 1.00 65.72  ? 257 LEU E CD2 1 
ATOM   12837 N N   . ILE E 2 256 ? 139.386 118.561 104.732 1.00 67.76  ? 258 ILE E N   1 
ATOM   12838 C CA  . ILE E 2 256 ? 138.354 119.017 103.804 1.00 67.76  ? 258 ILE E CA  1 
ATOM   12839 C C   . ILE E 2 256 ? 138.956 119.911 102.722 1.00 67.76  ? 258 ILE E C   1 
ATOM   12840 O O   . ILE E 2 256 ? 138.623 119.784 101.535 1.00 67.76  ? 258 ILE E O   1 
ATOM   12841 C CB  . ILE E 2 256 ? 137.218 119.721 104.567 1.00 67.76  ? 258 ILE E CB  1 
ATOM   12842 C CG1 . ILE E 2 256 ? 136.051 118.757 104.787 1.00 67.76  ? 258 ILE E CG1 1 
ATOM   12843 C CG2 . ILE E 2 256 ? 136.728 120.941 103.805 1.00 67.76  ? 258 ILE E CG2 1 
ATOM   12844 C CD1 . ILE E 2 256 ? 136.408 117.517 105.576 1.00 67.76  ? 258 ILE E CD1 1 
ATOM   12845 N N   . VAL E 2 257 ? 139.850 120.827 103.103 1.00 68.23  ? 259 VAL E N   1 
ATOM   12846 C CA  . VAL E 2 257 ? 140.471 121.678 102.087 1.00 68.23  ? 259 VAL E CA  1 
ATOM   12847 C C   . VAL E 2 257 ? 141.362 120.852 101.161 1.00 68.23  ? 259 VAL E C   1 
ATOM   12848 O O   . VAL E 2 257 ? 141.441 121.113 99.952  1.00 68.23  ? 259 VAL E O   1 
ATOM   12849 C CB  . VAL E 2 257 ? 141.241 122.843 102.733 1.00 68.23  ? 259 VAL E CB  1 
ATOM   12850 C CG1 . VAL E 2 257 ? 141.467 123.941 101.712 1.00 68.23  ? 259 VAL E CG1 1 
ATOM   12851 C CG2 . VAL E 2 257 ? 140.456 123.408 103.892 1.00 68.23  ? 259 VAL E CG2 1 
ATOM   12852 N N   . VAL E 2 258 ? 142.041 119.841 101.705 1.00 69.06  ? 260 VAL E N   1 
ATOM   12853 C CA  . VAL E 2 258 ? 142.839 118.954 100.864 1.00 69.06  ? 260 VAL E CA  1 
ATOM   12854 C C   . VAL E 2 258 ? 141.939 118.173 99.913  1.00 69.06  ? 260 VAL E C   1 
ATOM   12855 O O   . VAL E 2 258 ? 142.308 117.908 98.764  1.00 69.06  ? 260 VAL E O   1 
ATOM   12856 C CB  . VAL E 2 258 ? 143.700 118.026 101.741 1.00 69.06  ? 260 VAL E CB  1 
ATOM   12857 C CG1 . VAL E 2 258 ? 144.258 116.871 100.925 1.00 69.06  ? 260 VAL E CG1 1 
ATOM   12858 C CG2 . VAL E 2 258 ? 144.830 118.814 102.385 1.00 69.06  ? 260 VAL E CG2 1 
ATOM   12859 N N   . LEU E 2 259 ? 140.742 117.804 100.370 1.00 71.06  ? 261 LEU E N   1 
ATOM   12860 C CA  . LEU E 2 259 ? 139.772 117.158 99.493  1.00 71.06  ? 261 LEU E CA  1 
ATOM   12861 C C   . LEU E 2 259 ? 139.338 118.089 98.367  1.00 71.06  ? 261 LEU E C   1 
ATOM   12862 O O   . LEU E 2 259 ? 139.163 117.652 97.224  1.00 71.06  ? 261 LEU E O   1 
ATOM   12863 C CB  . LEU E 2 259 ? 138.567 116.692 100.312 1.00 71.06  ? 261 LEU E CB  1 
ATOM   12864 C CG  . LEU E 2 259 ? 137.261 116.388 99.578  1.00 71.06  ? 261 LEU E CG  1 
ATOM   12865 C CD1 . LEU E 2 259 ? 136.647 115.101 100.099 1.00 71.06  ? 261 LEU E CD1 1 
ATOM   12866 C CD2 . LEU E 2 259 ? 136.282 117.543 99.733  1.00 71.06  ? 261 LEU E CD2 1 
ATOM   12867 N N   . SER E 2 260 ? 139.146 119.372 98.673  1.00 75.01  ? 262 SER E N   1 
ATOM   12868 C CA  . SER E 2 260 ? 138.817 120.335 97.622  1.00 75.01  ? 262 SER E CA  1 
ATOM   12869 C C   . SER E 2 260 ? 139.953 120.453 96.608  1.00 75.01  ? 262 SER E C   1 
ATOM   12870 O O   . SER E 2 260 ? 139.717 120.540 95.396  1.00 75.01  ? 262 SER E O   1 
ATOM   12871 C CB  . SER E 2 260 ? 138.502 121.698 98.235  1.00 75.01  ? 262 SER E CB  1 
ATOM   12872 O OG  . SER E 2 260 ? 139.689 122.431 98.474  1.00 75.01  ? 262 SER E OG  1 
ATOM   12873 N N   . TRP E 2 261 ? 141.196 120.462 97.087  1.00 78.51  ? 263 TRP E N   1 
ATOM   12874 C CA  . TRP E 2 261 ? 142.333 120.487 96.169  1.00 78.51  ? 263 TRP E CA  1 
ATOM   12875 C C   . TRP E 2 261 ? 142.382 119.222 95.316  1.00 78.51  ? 263 TRP E C   1 
ATOM   12876 O O   . TRP E 2 261 ? 142.717 119.274 94.125  1.00 78.51  ? 263 TRP E O   1 
ATOM   12877 C CB  . TRP E 2 261 ? 143.630 120.664 96.952  1.00 78.51  ? 263 TRP E CB  1 
ATOM   12878 C CG  . TRP E 2 261 ? 143.690 121.959 97.687  1.00 78.51  ? 263 TRP E CG  1 
ATOM   12879 C CD1 . TRP E 2 261 ? 143.024 123.108 97.377  1.00 78.51  ? 263 TRP E CD1 1 
ATOM   12880 C CD2 . TRP E 2 261 ? 144.458 122.242 98.859  1.00 78.51  ? 263 TRP E CD2 1 
ATOM   12881 N NE1 . TRP E 2 261 ? 143.332 124.091 98.284  1.00 78.51  ? 263 TRP E NE1 1 
ATOM   12882 C CE2 . TRP E 2 261 ? 144.211 123.584 99.204  1.00 78.51  ? 263 TRP E CE2 1 
ATOM   12883 C CE3 . TRP E 2 261 ? 145.332 121.492 99.650  1.00 78.51  ? 263 TRP E CE3 1 
ATOM   12884 C CZ2 . TRP E 2 261 ? 144.805 124.190 100.305 1.00 78.51  ? 263 TRP E CZ2 1 
ATOM   12885 C CZ3 . TRP E 2 261 ? 145.921 122.096 100.742 1.00 78.51  ? 263 TRP E CZ3 1 
ATOM   12886 C CH2 . TRP E 2 261 ? 145.656 123.432 101.060 1.00 78.51  ? 263 TRP E CH2 1 
ATOM   12887 N N   . LEU E 2 262 ? 142.060 118.074 95.915  1.00 78.17  ? 264 LEU E N   1 
ATOM   12888 C CA  . LEU E 2 262 ? 141.945 116.835 95.152  1.00 78.17  ? 264 LEU E CA  1 
ATOM   12889 C C   . LEU E 2 262 ? 140.883 116.963 94.070  1.00 78.17  ? 264 LEU E C   1 
ATOM   12890 O O   . LEU E 2 262 ? 141.073 116.495 92.942  1.00 78.17  ? 264 LEU E O   1 
ATOM   12891 C CB  . LEU E 2 262 ? 141.629 115.672 96.097  1.00 78.17  ? 264 LEU E CB  1 
ATOM   12892 C CG  . LEU E 2 262 ? 140.815 114.472 95.603  1.00 78.17  ? 264 LEU E CG  1 
ATOM   12893 C CD1 . LEU E 2 262 ? 141.302 113.197 96.259  1.00 78.17  ? 264 LEU E CD1 1 
ATOM   12894 C CD2 . LEU E 2 262 ? 139.340 114.660 95.904  1.00 78.17  ? 264 LEU E CD2 1 
ATOM   12895 N N   . SER E 2 263 ? 139.754 117.590 94.405  1.00 80.26  ? 265 SER E N   1 
ATOM   12896 C CA  . SER E 2 263 ? 138.740 117.899 93.402  1.00 80.26  ? 265 SER E CA  1 
ATOM   12897 C C   . SER E 2 263 ? 139.333 118.721 92.271  1.00 80.26  ? 265 SER E C   1 
ATOM   12898 O O   . SER E 2 263 ? 139.025 118.494 91.096  1.00 80.26  ? 265 SER E O   1 
ATOM   12899 C CB  . SER E 2 263 ? 137.577 118.653 94.043  1.00 80.26  ? 265 SER E CB  1 
ATOM   12900 O OG  . SER E 2 263 ? 136.551 118.902 93.098  1.00 80.26  ? 265 SER E OG  1 
ATOM   12901 N N   . PHE E 2 264 ? 140.180 119.691 92.613  1.00 80.91  ? 266 PHE E N   1 
ATOM   12902 C CA  . PHE E 2 264 ? 140.839 120.485 91.582  1.00 80.91  ? 266 PHE E CA  1 
ATOM   12903 C C   . PHE E 2 264 ? 141.708 119.611 90.686  1.00 80.91  ? 266 PHE E C   1 
ATOM   12904 O O   . PHE E 2 264 ? 141.744 119.803 89.465  1.00 80.91  ? 266 PHE E O   1 
ATOM   12905 C CB  . PHE E 2 264 ? 141.677 121.593 92.214  1.00 80.91  ? 266 PHE E CB  1 
ATOM   12906 C CG  . PHE E 2 264 ? 140.983 122.915 92.260  1.00 80.91  ? 266 PHE E CG  1 
ATOM   12907 C CD1 . PHE E 2 264 ? 139.602 122.984 92.310  1.00 80.91  ? 266 PHE E CD1 1 
ATOM   12908 C CD2 . PHE E 2 264 ? 141.708 124.091 92.235  1.00 80.91  ? 266 PHE E CD2 1 
ATOM   12909 C CE1 . PHE E 2 264 ? 138.959 124.200 92.351  1.00 80.91  ? 266 PHE E CE1 1 
ATOM   12910 C CE2 . PHE E 2 264 ? 141.071 125.307 92.270  1.00 80.91  ? 266 PHE E CE2 1 
ATOM   12911 C CZ  . PHE E 2 264 ? 139.695 125.363 92.336  1.00 80.91  ? 266 PHE E CZ  1 
ATOM   12912 N N   . TRP E 2 265 ? 142.418 118.646 91.274  1.00 86.62  ? 267 TRP E N   1 
ATOM   12913 C CA  . TRP E 2 265 ? 143.250 117.755 90.472  1.00 86.62  ? 267 TRP E CA  1 
ATOM   12914 C C   . TRP E 2 265 ? 142.429 116.815 89.597  1.00 86.62  ? 267 TRP E C   1 
ATOM   12915 O O   . TRP E 2 265 ? 142.971 116.251 88.642  1.00 86.62  ? 267 TRP E O   1 
ATOM   12916 C CB  . TRP E 2 265 ? 144.181 116.941 91.371  1.00 86.62  ? 267 TRP E CB  1 
ATOM   12917 C CG  . TRP E 2 265 ? 145.623 117.323 91.237  1.00 86.62  ? 267 TRP E CG  1 
ATOM   12918 C CD1 . TRP E 2 265 ? 146.118 118.520 90.811  1.00 86.62  ? 267 TRP E CD1 1 
ATOM   12919 C CD2 . TRP E 2 265 ? 146.759 116.495 91.516  1.00 86.62  ? 267 TRP E CD2 1 
ATOM   12920 N NE1 . TRP E 2 265 ? 147.491 118.493 90.815  1.00 86.62  ? 267 TRP E NE1 1 
ATOM   12921 C CE2 . TRP E 2 265 ? 147.909 117.261 91.244  1.00 86.62  ? 267 TRP E CE2 1 
ATOM   12922 C CE3 . TRP E 2 265 ? 146.915 115.183 91.973  1.00 86.62  ? 267 TRP E CE3 1 
ATOM   12923 C CZ2 . TRP E 2 265 ? 149.198 116.758 91.413  1.00 86.62  ? 267 TRP E CZ2 1 
ATOM   12924 C CZ3 . TRP E 2 265 ? 148.194 114.685 92.140  1.00 86.62  ? 267 TRP E CZ3 1 
ATOM   12925 C CH2 . TRP E 2 265 ? 149.319 115.471 91.861  1.00 86.62  ? 267 TRP E CH2 1 
ATOM   12926 N N   . ILE E 2 266 ? 141.141 116.629 89.904  1.00 90.99  ? 268 ILE E N   1 
ATOM   12927 C CA  . ILE E 2 266 ? 140.283 115.803 89.059  1.00 90.99  ? 268 ILE E CA  1 
ATOM   12928 C C   . ILE E 2 266 ? 140.149 116.445 87.679  1.00 90.99  ? 268 ILE E C   1 
ATOM   12929 O O   . ILE E 2 266 ? 140.313 117.658 87.505  1.00 90.99  ? 268 ILE E O   1 
ATOM   12930 C CB  . ILE E 2 266 ? 138.912 115.595 89.729  1.00 90.99  ? 268 ILE E CB  1 
ATOM   12931 C CG1 . ILE E 2 266 ? 139.082 114.898 91.081  1.00 90.99  ? 268 ILE E CG1 1 
ATOM   12932 C CG2 . ILE E 2 266 ? 137.964 114.772 88.864  1.00 90.99  ? 268 ILE E CG2 1 
ATOM   12933 C CD1 . ILE E 2 266 ? 139.278 113.399 90.981  1.00 90.99  ? 268 ILE E CD1 1 
ATOM   12934 N N   . ASN E 2 267 ? 139.869 115.607 86.683  1.00 101.54 ? 269 ASN E N   1 
ATOM   12935 C CA  . ASN E 2 267 ? 139.787 116.063 85.303  1.00 101.54 ? 269 ASN E CA  1 
ATOM   12936 C C   . ASN E 2 267 ? 138.767 117.189 85.169  1.00 101.54 ? 269 ASN E C   1 
ATOM   12937 O O   . ASN E 2 267 ? 137.598 117.007 85.535  1.00 101.54 ? 269 ASN E O   1 
ATOM   12938 C CB  . ASN E 2 267 ? 139.399 114.900 84.389  1.00 101.54 ? 269 ASN E CB  1 
ATOM   12939 C CG  . ASN E 2 267 ? 139.974 115.033 82.993  1.00 101.54 ? 269 ASN E CG  1 
ATOM   12940 O OD1 . ASN E 2 267 ? 140.459 116.095 82.605  1.00 101.54 ? 269 ASN E OD1 1 
ATOM   12941 N ND2 . ASN E 2 267 ? 139.918 113.950 82.227  1.00 101.54 ? 269 ASN E ND2 1 
ATOM   12942 N N   . PRO E 2 268 ? 139.157 118.348 84.654  1.00 106.55 ? 270 PRO E N   1 
ATOM   12943 C CA  . PRO E 2 268 ? 138.193 119.417 84.383  1.00 106.55 ? 270 PRO E CA  1 
ATOM   12944 C C   . PRO E 2 268 ? 137.350 119.064 83.162  1.00 106.55 ? 270 PRO E C   1 
ATOM   12945 O O   . PRO E 2 268 ? 137.458 117.977 82.601  1.00 106.55 ? 270 PRO E O   1 
ATOM   12946 C CB  . PRO E 2 268 ? 139.078 120.641 84.136  1.00 106.55 ? 270 PRO E CB  1 
ATOM   12947 C CG  . PRO E 2 268 ? 140.374 120.084 83.670  1.00 106.55 ? 270 PRO E CG  1 
ATOM   12948 C CD  . PRO E 2 268 ? 140.540 118.752 84.344  1.00 106.55 ? 270 PRO E CD  1 
ATOM   12949 N N   . ASP E 2 269 ? 136.480 120.006 82.785  1.00 107.67 ? 271 ASP E N   1 
ATOM   12950 C CA  . ASP E 2 269 ? 135.515 119.839 81.691  1.00 107.67 ? 271 ASP E CA  1 
ATOM   12951 C C   . ASP E 2 269 ? 134.764 118.510 81.796  1.00 107.67 ? 271 ASP E C   1 
ATOM   12952 O O   . ASP E 2 269 ? 134.307 117.950 80.796  1.00 107.67 ? 271 ASP E O   1 
ATOM   12953 C CB  . ASP E 2 269 ? 136.174 120.018 80.310  1.00 107.67 ? 271 ASP E CB  1 
ATOM   12954 C CG  . ASP E 2 269 ? 137.179 118.931 79.968  1.00 107.67 ? 271 ASP E CG  1 
ATOM   12955 O OD1 . ASP E 2 269 ? 136.777 117.897 79.394  1.00 107.67 ? 271 ASP E OD1 1 
ATOM   12956 O OD2 . ASP E 2 269 ? 138.382 119.121 80.252  1.00 107.67 ? 271 ASP E OD2 1 
ATOM   12957 N N   . ALA E 2 270 ? 134.637 117.999 83.029  1.00 103.82 ? 272 ALA E N   1 
ATOM   12958 C CA  . ALA E 2 270 ? 133.812 116.833 83.361  1.00 103.82 ? 272 ALA E CA  1 
ATOM   12959 C C   . ALA E 2 270 ? 133.054 117.194 84.637  1.00 103.82 ? 272 ALA E C   1 
ATOM   12960 O O   . ALA E 2 270 ? 133.487 116.878 85.750  1.00 103.82 ? 272 ALA E O   1 
ATOM   12961 C CB  . ALA E 2 270 ? 134.661 115.577 83.525  1.00 103.82 ? 272 ALA E CB  1 
ATOM   12962 N N   . SER E 2 271 ? 131.911 117.858 84.459  1.00 98.91  ? 273 SER E N   1 
ATOM   12963 C CA  . SER E 2 271 ? 131.162 118.509 85.529  1.00 98.91  ? 273 SER E CA  1 
ATOM   12964 C C   . SER E 2 271 ? 130.746 117.572 86.658  1.00 98.91  ? 273 SER E C   1 
ATOM   12965 O O   . SER E 2 271 ? 130.920 117.886 87.847  1.00 98.91  ? 273 SER E O   1 
ATOM   12966 C CB  . SER E 2 271 ? 129.920 119.184 84.933  1.00 98.91  ? 273 SER E CB  1 
ATOM   12967 O OG  . SER E 2 271 ? 129.357 120.118 85.835  1.00 98.91  ? 273 SER E OG  1 
ATOM   12968 N N   . ALA E 2 272 ? 130.189 116.422 86.277  1.00 94.74  ? 274 ALA E N   1 
ATOM   12969 C CA  . ALA E 2 272 ? 129.517 115.501 87.184  1.00 94.74  ? 274 ALA E CA  1 
ATOM   12970 C C   . ALA E 2 272 ? 130.361 115.167 88.401  1.00 94.74  ? 274 ALA E C   1 
ATOM   12971 O O   . ALA E 2 272 ? 129.857 115.173 89.525  1.00 94.74  ? 274 ALA E O   1 
ATOM   12972 C CB  . ALA E 2 272 ? 129.129 114.220 86.442  1.00 94.74  ? 274 ALA E CB  1 
ATOM   12973 N N   . ALA E 2 273 ? 131.630 114.820 88.191  1.00 94.14  ? 275 ALA E N   1 
ATOM   12974 C CA  . ALA E 2 273 ? 132.531 114.562 89.310  1.00 94.14  ? 275 ALA E CA  1 
ATOM   12975 C C   . ALA E 2 273 ? 132.801 115.815 90.136  1.00 94.14  ? 275 ALA E C   1 
ATOM   12976 O O   . ALA E 2 273 ? 132.800 115.781 91.371  1.00 94.14  ? 275 ALA E O   1 
ATOM   12977 C CB  . ALA E 2 273 ? 133.844 113.967 88.787  1.00 94.14  ? 275 ALA E CB  1 
ATOM   12978 N N   . ARG E 2 274 ? 133.047 116.936 89.454  1.00 88.02  ? 276 ARG E N   1 
ATOM   12979 C CA  . ARG E 2 274 ? 133.564 118.125 90.131  1.00 88.02  ? 276 ARG E CA  1 
ATOM   12980 C C   . ARG E 2 274 ? 132.550 118.733 91.090  1.00 88.02  ? 276 ARG E C   1 
ATOM   12981 O O   . ARG E 2 274 ? 132.857 118.956 92.266  1.00 88.02  ? 276 ARG E O   1 
ATOM   12982 C CB  . ARG E 2 274 ? 134.012 119.160 89.097  1.00 88.02  ? 276 ARG E CB  1 
ATOM   12983 C CG  . ARG E 2 274 ? 135.090 118.674 88.148  1.00 88.02  ? 276 ARG E CG  1 
ATOM   12984 C CD  . ARG E 2 274 ? 136.318 118.261 88.931  1.00 88.02  ? 276 ARG E CD  1 
ATOM   12985 N NE  . ARG E 2 274 ? 137.044 119.422 89.428  1.00 88.02  ? 276 ARG E NE  1 
ATOM   12986 C CZ  . ARG E 2 274 ? 138.012 120.045 88.770  1.00 88.02  ? 276 ARG E CZ  1 
ATOM   12987 N NH1 . ARG E 2 274 ? 138.435 119.616 87.593  1.00 88.02  ? 276 ARG E NH1 1 
ATOM   12988 N NH2 . ARG E 2 274 ? 138.575 121.120 89.312  1.00 88.02  ? 276 ARG E NH2 1 
ATOM   12989 N N   . VAL E 2 275 ? 131.345 119.026 90.607  1.00 80.35  ? 277 VAL E N   1 
ATOM   12990 C CA  . VAL E 2 275 ? 130.407 119.861 91.374  1.00 80.35  ? 277 VAL E CA  1 
ATOM   12991 C C   . VAL E 2 275 ? 130.100 119.281 92.759  1.00 80.35  ? 277 VAL E C   1 
ATOM   12992 O O   . VAL E 2 275 ? 130.216 120.015 93.762  1.00 80.35  ? 277 VAL E O   1 
ATOM   12993 C CB  . VAL E 2 275 ? 129.114 120.110 90.580  1.00 80.35  ? 277 VAL E CB  1 
ATOM   12994 C CG1 . VAL E 2 275 ? 127.937 120.329 91.520  1.00 80.35  ? 277 VAL E CG1 1 
ATOM   12995 C CG2 . VAL E 2 275 ? 129.285 121.306 89.657  1.00 80.35  ? 277 VAL E CG2 1 
ATOM   12996 N N   . PRO E 2 276 ? 129.697 117.984 92.883  1.00 80.27  ? 278 PRO E N   1 
ATOM   12997 C CA  . PRO E 2 276 ? 129.378 117.439 94.212  1.00 80.27  ? 278 PRO E CA  1 
ATOM   12998 C C   . PRO E 2 276 ? 130.514 117.566 95.208  1.00 80.27  ? 278 PRO E C   1 
ATOM   12999 O O   . PRO E 2 276 ? 130.271 117.818 96.390  1.00 80.27  ? 278 PRO E O   1 
ATOM   13000 C CB  . PRO E 2 276 ? 129.046 115.967 93.931  1.00 80.27  ? 278 PRO E CB  1 
ATOM   13001 C CG  . PRO E 2 276 ? 129.572 115.696 92.581  1.00 80.27  ? 278 PRO E CG  1 
ATOM   13002 C CD  . PRO E 2 276 ? 129.429 116.982 91.844  1.00 80.27  ? 278 PRO E CD  1 
ATOM   13003 N N   . LEU E 2 277 ? 131.753 117.376 94.754  1.00 80.87  ? 279 LEU E N   1 
ATOM   13004 C CA  . LEU E 2 277 ? 132.898 117.480 95.652  1.00 80.87  ? 279 LEU E CA  1 
ATOM   13005 C C   . LEU E 2 277 ? 132.952 118.850 96.319  1.00 80.87  ? 279 LEU E C   1 
ATOM   13006 O O   . LEU E 2 277 ? 133.017 118.958 97.550  1.00 80.87  ? 279 LEU E O   1 
ATOM   13007 C CB  . LEU E 2 277 ? 134.182 117.183 94.868  1.00 80.87  ? 279 LEU E CB  1 
ATOM   13008 C CG  . LEU E 2 277 ? 134.815 115.842 95.246  1.00 80.87  ? 279 LEU E CG  1 
ATOM   13009 C CD1 . LEU E 2 277 ? 136.146 115.607 94.569  1.00 80.87  ? 279 LEU E CD1 1 
ATOM   13010 C CD2 . LEU E 2 277 ? 134.986 115.775 96.752  1.00 80.87  ? 279 LEU E CD2 1 
ATOM   13011 N N   . GLY E 2 278 ? 132.886 119.913 95.515  1.00 77.87  ? 280 GLY E N   1 
ATOM   13012 C CA  . GLY E 2 278 ? 132.947 121.256 96.072  1.00 77.87  ? 280 GLY E CA  1 
ATOM   13013 C C   . GLY E 2 278 ? 131.767 121.577 96.968  1.00 77.87  ? 280 GLY E C   1 
ATOM   13014 O O   . GLY E 2 278 ? 131.933 122.126 98.066  1.00 77.87  ? 280 GLY E O   1 
ATOM   13015 N N   . ILE E 2 279 ? 130.553 121.244 96.515  1.00 76.15  ? 281 ILE E N   1 
ATOM   13016 C CA  . ILE E 2 279 ? 129.387 121.590 97.324  1.00 76.15  ? 281 ILE E CA  1 
ATOM   13017 C C   . ILE E 2 279 ? 129.424 120.837 98.649  1.00 76.15  ? 281 ILE E C   1 
ATOM   13018 O O   . ILE E 2 279 ? 129.125 121.402 99.709  1.00 76.15  ? 281 ILE E O   1 
ATOM   13019 C CB  . ILE E 2 279 ? 128.077 121.333 96.552  1.00 76.15  ? 281 ILE E CB  1 
ATOM   13020 C CG1 . ILE E 2 279 ? 126.863 121.582 97.444  1.00 76.15  ? 281 ILE E CG1 1 
ATOM   13021 C CG2 . ILE E 2 279 ? 127.995 119.927 96.054  1.00 76.15  ? 281 ILE E CG2 1 
ATOM   13022 C CD1 . ILE E 2 279 ? 126.875 122.917 98.112  1.00 76.15  ? 281 ILE E CD1 1 
ATOM   13023 N N   . PHE E 2 280 ? 129.801 119.557 98.617  1.00 76.56  ? 282 PHE E N   1 
ATOM   13024 C CA  . PHE E 2 280 ? 129.844 118.764 99.837  1.00 76.56  ? 282 PHE E CA  1 
ATOM   13025 C C   . PHE E 2 280 ? 130.922 119.274 100.781 1.00 76.56  ? 282 PHE E C   1 
ATOM   13026 O O   . PHE E 2 280 ? 130.734 119.285 102.000 1.00 76.56  ? 282 PHE E O   1 
ATOM   13027 C CB  . PHE E 2 280 ? 130.061 117.294 99.491  1.00 76.56  ? 282 PHE E CB  1 
ATOM   13028 C CG  . PHE E 2 280 ? 128.842 116.442 99.698  1.00 76.56  ? 282 PHE E CG  1 
ATOM   13029 C CD1 . PHE E 2 280 ? 128.281 116.303 100.956 1.00 76.56  ? 282 PHE E CD1 1 
ATOM   13030 C CD2 . PHE E 2 280 ? 128.238 115.805 98.626  1.00 76.56  ? 282 PHE E CD2 1 
ATOM   13031 C CE1 . PHE E 2 280 ? 127.153 115.525 101.143 1.00 76.56  ? 282 PHE E CE1 1 
ATOM   13032 C CE2 . PHE E 2 280 ? 127.114 115.024 98.807  1.00 76.56  ? 282 PHE E CE2 1 
ATOM   13033 C CZ  . PHE E 2 280 ? 126.570 114.886 100.066 1.00 76.56  ? 282 PHE E CZ  1 
ATOM   13034 N N   . SER E 2 281 ? 132.065 119.699 100.236 1.00 74.09  ? 283 SER E N   1 
ATOM   13035 C CA  . SER E 2 281 ? 133.087 120.323 101.071 1.00 74.09  ? 283 SER E CA  1 
ATOM   13036 C C   . SER E 2 281 ? 132.529 121.545 101.793 1.00 74.09  ? 283 SER E C   1 
ATOM   13037 O O   . SER E 2 281 ? 132.687 121.694 103.012 1.00 74.09  ? 283 SER E O   1 
ATOM   13038 C CB  . SER E 2 281 ? 134.297 120.706 100.217 1.00 74.09  ? 283 SER E CB  1 
ATOM   13039 O OG  . SER E 2 281 ? 134.944 121.853 100.740 1.00 74.09  ? 283 SER E OG  1 
ATOM   13040 N N   . VAL E 2 282 ? 131.858 122.428 101.048 1.00 70.26  ? 284 VAL E N   1 
ATOM   13041 C CA  . VAL E 2 282 ? 131.326 123.653 101.648 1.00 70.26  ? 284 VAL E CA  1 
ATOM   13042 C C   . VAL E 2 282 ? 130.304 123.321 102.731 1.00 70.26  ? 284 VAL E C   1 
ATOM   13043 O O   . VAL E 2 282 ? 130.318 123.899 103.826 1.00 70.26  ? 284 VAL E O   1 
ATOM   13044 C CB  . VAL E 2 282 ? 130.724 124.567 100.566 1.00 70.26  ? 284 VAL E CB  1 
ATOM   13045 C CG1 . VAL E 2 282 ? 130.023 125.751 101.205 1.00 70.26  ? 284 VAL E CG1 1 
ATOM   13046 C CG2 . VAL E 2 282 ? 131.806 125.046 99.616  1.00 70.26  ? 284 VAL E CG2 1 
ATOM   13047 N N   . LEU E 2 283 ? 129.399 122.385 102.438 1.00 71.45  ? 285 LEU E N   1 
ATOM   13048 C CA  . LEU E 2 283 ? 128.353 122.028 103.396 1.00 71.45  ? 285 LEU E CA  1 
ATOM   13049 C C   . LEU E 2 283 ? 128.932 121.368 104.641 1.00 71.45  ? 285 LEU E C   1 
ATOM   13050 O O   . LEU E 2 283 ? 128.491 121.651 105.762 1.00 71.45  ? 285 LEU E O   1 
ATOM   13051 C CB  . LEU E 2 283 ? 127.325 121.119 102.723 1.00 71.45  ? 285 LEU E CB  1 
ATOM   13052 C CG  . LEU E 2 283 ? 126.611 121.672 101.487 1.00 71.45  ? 285 LEU E CG  1 
ATOM   13053 C CD1 . LEU E 2 283 ? 125.218 121.118 101.379 1.00 71.45  ? 285 LEU E CD1 1 
ATOM   13054 C CD2 . LEU E 2 283 ? 126.524 123.193 101.569 1.00 71.45  ? 285 LEU E CD2 1 
ATOM   13055 N N   . SER E 2 284 ? 129.912 120.479 104.465 1.00 71.20  ? 286 SER E N   1 
ATOM   13056 C CA  . SER E 2 284 ? 130.562 119.848 105.606 1.00 71.20  ? 286 SER E CA  1 
ATOM   13057 C C   . SER E 2 284 ? 131.236 120.888 106.487 1.00 71.20  ? 286 SER E C   1 
ATOM   13058 O O   . SER E 2 284 ? 131.133 120.839 107.719 1.00 71.20  ? 286 SER E O   1 
ATOM   13059 C CB  . SER E 2 284 ? 131.579 118.817 105.118 1.00 71.20  ? 286 SER E CB  1 
ATOM   13060 O OG  . SER E 2 284 ? 132.537 118.530 106.121 1.00 71.20  ? 286 SER E OG  1 
ATOM   13061 N N   . LEU E 2 285 ? 131.924 121.849 105.868 1.00 72.40  ? 287 LEU E N   1 
ATOM   13062 C CA  . LEU E 2 285 ? 132.580 122.895 106.643 1.00 72.40  ? 287 LEU E CA  1 
ATOM   13063 C C   . LEU E 2 285 ? 131.568 123.755 107.391 1.00 72.40  ? 287 LEU E C   1 
ATOM   13064 O O   . LEU E 2 285 ? 131.783 124.104 108.559 1.00 72.40  ? 287 LEU E O   1 
ATOM   13065 C CB  . LEU E 2 285 ? 133.444 123.747 105.718 1.00 72.40  ? 287 LEU E CB  1 
ATOM   13066 C CG  . LEU E 2 285 ? 134.866 123.984 106.206 1.00 72.40  ? 287 LEU E CG  1 
ATOM   13067 C CD1 . LEU E 2 285 ? 135.484 122.681 106.661 1.00 72.40  ? 287 LEU E CD1 1 
ATOM   13068 C CD2 . LEU E 2 285 ? 135.657 124.553 105.059 1.00 72.40  ? 287 LEU E CD2 1 
ATOM   13069 N N   . ALA E 2 286 ? 130.458 124.105 106.738 1.00 75.65  ? 288 ALA E N   1 
ATOM   13070 C CA  . ALA E 2 286 ? 129.433 124.906 107.401 1.00 75.65  ? 288 ALA E CA  1 
ATOM   13071 C C   . ALA E 2 286 ? 128.839 124.163 108.590 1.00 75.65  ? 288 ALA E C   1 
ATOM   13072 O O   . ALA E 2 286 ? 128.637 124.741 109.667 1.00 75.65  ? 288 ALA E O   1 
ATOM   13073 C CB  . ALA E 2 286 ? 128.341 125.286 106.401 1.00 75.65  ? 288 ALA E CB  1 
ATOM   13074 N N   . SER E 2 287 ? 128.548 122.872 108.410 1.00 78.15  ? 289 SER E N   1 
ATOM   13075 C CA  . SER E 2 287 ? 128.001 122.076 109.505 1.00 78.15  ? 289 SER E CA  1 
ATOM   13076 C C   . SER E 2 287 ? 128.998 121.958 110.649 1.00 78.15  ? 289 SER E C   1 
ATOM   13077 O O   . SER E 2 287 ? 128.614 122.019 111.823 1.00 78.15  ? 289 SER E O   1 
ATOM   13078 C CB  . SER E 2 287 ? 127.593 120.696 108.992 1.00 78.15  ? 289 SER E CB  1 
ATOM   13079 O OG  . SER E 2 287 ? 126.452 120.214 109.679 1.00 78.15  ? 289 SER E OG  1 
ATOM   13080 N N   . GLU E 2 288 ? 130.283 121.784 110.326 1.00 83.08  ? 290 GLU E N   1 
ATOM   13081 C CA  . GLU E 2 288 ? 131.315 121.745 111.359 1.00 83.08  ? 290 GLU E CA  1 
ATOM   13082 C C   . GLU E 2 288 ? 131.359 123.048 112.145 1.00 83.08  ? 290 GLU E C   1 
ATOM   13083 O O   . GLU E 2 288 ? 131.445 123.037 113.379 1.00 83.08  ? 290 GLU E O   1 
ATOM   13084 C CB  . GLU E 2 288 ? 132.675 121.459 110.722 1.00 83.08  ? 290 GLU E CB  1 
ATOM   13085 C CG  . GLU E 2 288 ? 133.848 121.571 111.678 1.00 83.08  ? 290 GLU E CG  1 
ATOM   13086 C CD  . GLU E 2 288 ? 135.026 120.713 111.259 1.00 83.08  ? 290 GLU E CD  1 
ATOM   13087 O OE1 . GLU E 2 288 ? 135.293 120.616 110.043 1.00 83.08  ? 290 GLU E OE1 1 
ATOM   13088 O OE2 . GLU E 2 288 ? 135.683 120.135 112.148 1.00 83.08  ? 290 GLU E OE2 1 
ATOM   13089 N N   . CYS E 2 289 ? 131.300 124.184 111.442 1.00 86.47  ? 291 CYS E N   1 
ATOM   13090 C CA  . CYS E 2 289 ? 131.308 125.474 112.123 1.00 86.47  ? 291 CYS E CA  1 
ATOM   13091 C C   . CYS E 2 289 ? 130.102 125.630 113.037 1.00 86.47  ? 291 CYS E C   1 
ATOM   13092 O O   . CYS E 2 289 ? 130.245 126.082 114.180 1.00 86.47  ? 291 CYS E O   1 
ATOM   13093 C CB  . CYS E 2 289 ? 131.343 126.610 111.100 1.00 86.47  ? 291 CYS E CB  1 
ATOM   13094 S SG  . CYS E 2 289 ? 130.940 128.236 111.777 1.00 86.47  ? 291 CYS E SG  1 
ATOM   13095 N N   . THR E 2 290 ? 128.914 125.252 112.560 1.00 83.73  ? 292 THR E N   1 
ATOM   13096 C CA  . THR E 2 290 ? 127.719 125.361 113.390 1.00 83.73  ? 292 THR E CA  1 
ATOM   13097 C C   . THR E 2 290 ? 127.809 124.470 114.625 1.00 83.73  ? 292 THR E C   1 
ATOM   13098 O O   . THR E 2 290 ? 127.493 124.912 115.738 1.00 83.73  ? 292 THR E O   1 
ATOM   13099 C CB  . THR E 2 290 ? 126.476 125.008 112.572 1.00 83.73  ? 292 THR E CB  1 
ATOM   13100 O OG1 . THR E 2 290 ? 126.263 126.008 111.568 1.00 83.73  ? 292 THR E OG1 1 
ATOM   13101 C CG2 . THR E 2 290 ? 125.249 124.927 113.468 1.00 83.73  ? 292 THR E CG2 1 
ATOM   13102 N N   . THR E 2 291 ? 128.258 123.224 114.451 1.00 90.10  ? 293 THR E N   1 
ATOM   13103 C CA  . THR E 2 291 ? 128.355 122.305 115.580 1.00 90.10  ? 293 THR E CA  1 
ATOM   13104 C C   . THR E 2 291 ? 129.379 122.783 116.601 1.00 90.10  ? 293 THR E C   1 
ATOM   13105 O O   . THR E 2 291 ? 129.160 122.657 117.811 1.00 90.10  ? 293 THR E O   1 
ATOM   13106 C CB  . THR E 2 291 ? 128.709 120.899 115.095 1.00 90.10  ? 293 THR E CB  1 
ATOM   13107 O OG1 . THR E 2 291 ? 129.819 120.967 114.191 1.00 90.10  ? 293 THR E OG1 1 
ATOM   13108 C CG2 . THR E 2 291 ? 127.522 120.262 114.390 1.00 90.10  ? 293 THR E CG2 1 
ATOM   13109 N N   . LEU E 2 292 ? 130.504 123.331 116.138 1.00 84.05  ? 294 LEU E N   1 
ATOM   13110 C CA  . LEU E 2 292 ? 131.540 123.756 117.068 1.00 84.05  ? 294 LEU E CA  1 
ATOM   13111 C C   . LEU E 2 292 ? 131.269 125.122 117.680 1.00 84.05  ? 294 LEU E C   1 
ATOM   13112 O O   . LEU E 2 292 ? 131.890 125.463 118.692 1.00 84.05  ? 294 LEU E O   1 
ATOM   13113 C CB  . LEU E 2 292 ? 132.899 123.768 116.372 1.00 84.05  ? 294 LEU E CB  1 
ATOM   13114 C CG  . LEU E 2 292 ? 133.714 122.495 116.587 1.00 84.05  ? 294 LEU E CG  1 
ATOM   13115 C CD1 . LEU E 2 292 ? 134.057 122.328 118.061 1.00 84.05  ? 294 LEU E CD1 1 
ATOM   13116 C CD2 . LEU E 2 292 ? 132.988 121.268 116.053 1.00 84.05  ? 294 LEU E CD2 1 
ATOM   13117 N N   . ALA E 2 293 ? 130.366 125.910 117.099 1.00 82.42  ? 295 ALA E N   1 
ATOM   13118 C CA  . ALA E 2 293 ? 129.993 127.181 117.700 1.00 82.42  ? 295 ALA E CA  1 
ATOM   13119 C C   . ALA E 2 293 ? 128.746 127.093 118.567 1.00 82.42  ? 295 ALA E C   1 
ATOM   13120 O O   . ALA E 2 293 ? 128.512 127.995 119.379 1.00 82.42  ? 295 ALA E O   1 
ATOM   13121 C CB  . ALA E 2 293 ? 129.777 128.239 116.612 1.00 82.42  ? 295 ALA E CB  1 
ATOM   13122 N N   . ALA E 2 294 ? 127.941 126.040 118.412 1.00 84.94  ? 296 ALA E N   1 
ATOM   13123 C CA  . ALA E 2 294 ? 126.748 125.901 119.242 1.00 84.94  ? 296 ALA E CA  1 
ATOM   13124 C C   . ALA E 2 294 ? 127.105 125.696 120.711 1.00 84.94  ? 296 ALA E C   1 
ATOM   13125 O O   . ALA E 2 294 ? 126.454 126.262 121.597 1.00 84.94  ? 296 ALA E O   1 
ATOM   13126 C CB  . ALA E 2 294 ? 125.888 124.745 118.733 1.00 84.94  ? 296 ALA E CB  1 
ATOM   13127 N N   . GLU E 2 295 ? 128.134 124.892 120.989 1.00 85.19  ? 297 GLU E N   1 
ATOM   13128 C CA  . GLU E 2 295 ? 128.432 124.517 122.369 1.00 85.19  ? 297 GLU E CA  1 
ATOM   13129 C C   . GLU E 2 295 ? 129.021 125.684 123.153 1.00 85.19  ? 297 GLU E C   1 
ATOM   13130 O O   . GLU E 2 295 ? 128.754 125.830 124.351 1.00 85.19  ? 297 GLU E O   1 
ATOM   13131 C CB  . GLU E 2 295 ? 129.375 123.309 122.380 1.00 85.19  ? 297 GLU E CB  1 
ATOM   13132 C CG  . GLU E 2 295 ? 129.939 122.914 123.744 1.00 85.19  ? 297 GLU E CG  1 
ATOM   13133 C CD  . GLU E 2 295 ? 131.146 123.735 124.160 1.00 85.19  ? 297 GLU E CD  1 
ATOM   13134 O OE1 . GLU E 2 295 ? 131.539 123.657 125.343 1.00 85.19  ? 297 GLU E OE1 1 
ATOM   13135 O OE2 . GLU E 2 295 ? 131.709 124.447 123.303 1.00 85.19  ? 297 GLU E OE2 1 
ATOM   13136 N N   . LEU E 2 296 ? 129.828 126.516 122.501 1.00 76.81  ? 298 LEU E N   1 
ATOM   13137 C CA  . LEU E 2 296 ? 130.509 127.596 123.194 1.00 76.81  ? 298 LEU E CA  1 
ATOM   13138 C C   . LEU E 2 296 ? 129.516 128.666 123.646 1.00 76.81  ? 298 LEU E C   1 
ATOM   13139 O O   . LEU E 2 296 ? 128.450 128.829 123.047 1.00 76.81  ? 298 LEU E O   1 
ATOM   13140 C CB  . LEU E 2 296 ? 131.565 128.219 122.287 1.00 76.81  ? 298 LEU E CB  1 
ATOM   13141 C CG  . LEU E 2 296 ? 132.858 127.416 122.176 1.00 76.81  ? 298 LEU E CG  1 
ATOM   13142 C CD1 . LEU E 2 296 ? 133.853 128.133 121.285 1.00 76.81  ? 298 LEU E CD1 1 
ATOM   13143 C CD2 . LEU E 2 296 ? 133.437 127.182 123.558 1.00 76.81  ? 298 LEU E CD2 1 
ATOM   13144 N N   . PRO E 2 297 ? 129.839 129.403 124.709 1.00 66.56  ? 299 PRO E N   1 
ATOM   13145 C CA  . PRO E 2 297 ? 128.951 130.483 125.149 1.00 66.56  ? 299 PRO E CA  1 
ATOM   13146 C C   . PRO E 2 297 ? 128.823 131.561 124.084 1.00 66.56  ? 299 PRO E C   1 
ATOM   13147 O O   . PRO E 2 297 ? 129.760 131.842 123.335 1.00 66.56  ? 299 PRO E O   1 
ATOM   13148 C CB  . PRO E 2 297 ? 129.639 131.020 126.409 1.00 66.56  ? 299 PRO E CB  1 
ATOM   13149 C CG  . PRO E 2 297 ? 131.065 130.620 126.258 1.00 66.56  ? 299 PRO E CG  1 
ATOM   13150 C CD  . PRO E 2 297 ? 131.034 129.296 125.562 1.00 66.56  ? 299 PRO E CD  1 
ATOM   13151 N N   . LYS E 2 298 ? 127.641 132.167 124.025 1.00 55.10  ? 300 LYS E N   1 
ATOM   13152 C CA  . LYS E 2 298 ? 127.363 133.200 123.037 1.00 55.10  ? 300 LYS E CA  1 
ATOM   13153 C C   . LYS E 2 298 ? 127.940 134.527 123.509 1.00 55.10  ? 300 LYS E C   1 
ATOM   13154 O O   . LYS E 2 298 ? 127.496 135.080 124.521 1.00 55.10  ? 300 LYS E O   1 
ATOM   13155 C CB  . LYS E 2 298 ? 125.859 133.315 122.800 1.00 55.10  ? 300 LYS E CB  1 
ATOM   13156 C CG  . LYS E 2 298 ? 125.012 132.904 123.991 1.00 55.10  ? 300 LYS E CG  1 
ATOM   13157 C CD  . LYS E 2 298 ? 123.548 132.776 123.603 1.00 55.10  ? 300 LYS E CD  1 
ATOM   13158 C CE  . LYS E 2 298 ? 123.370 131.849 122.412 1.00 55.10  ? 300 LYS E CE  1 
ATOM   13159 N NZ  . LYS E 2 298 ? 123.859 130.474 122.696 1.00 55.10  ? 300 LYS E NZ  1 
ATOM   13160 N N   . VAL E 2 299 ? 128.927 135.039 122.777 1.00 55.48  ? 301 VAL E N   1 
ATOM   13161 C CA  . VAL E 2 299 ? 129.589 136.289 123.118 1.00 55.48  ? 301 VAL E CA  1 
ATOM   13162 C C   . VAL E 2 299 ? 129.601 137.188 121.890 1.00 55.48  ? 301 VAL E C   1 
ATOM   13163 O O   . VAL E 2 299 ? 129.563 136.716 120.750 1.00 55.48  ? 301 VAL E O   1 
ATOM   13164 C CB  . VAL E 2 299 ? 131.020 136.050 123.649 1.00 55.48  ? 301 VAL E CB  1 
ATOM   13165 C CG1 . VAL E 2 299 ? 131.982 135.791 122.504 1.00 55.48  ? 301 VAL E CG1 1 
ATOM   13166 C CG2 . VAL E 2 299 ? 131.477 137.224 124.497 1.00 55.48  ? 301 VAL E CG2 1 
ATOM   13167 N N   . SER E 2 300 ? 129.647 138.499 122.133 1.00 55.24  ? 302 SER E N   1 
ATOM   13168 C CA  . SER E 2 300 ? 129.494 139.465 121.049 1.00 55.24  ? 302 SER E CA  1 
ATOM   13169 C C   . SER E 2 300 ? 130.691 139.450 120.105 1.00 55.24  ? 302 SER E C   1 
ATOM   13170 O O   . SER E 2 300 ? 130.525 139.397 118.881 1.00 55.24  ? 302 SER E O   1 
ATOM   13171 C CB  . SER E 2 300 ? 129.286 140.864 121.626 1.00 55.24  ? 302 SER E CB  1 
ATOM   13172 O OG  . SER E 2 300 ? 129.425 141.850 120.619 1.00 55.24  ? 302 SER E OG  1 
ATOM   13173 N N   . TYR E 2 301 ? 131.902 139.500 120.650 1.00 61.05  ? 303 TYR E N   1 
ATOM   13174 C CA  . TYR E 2 301 ? 133.080 139.645 119.808 1.00 61.05  ? 303 TYR E CA  1 
ATOM   13175 C C   . TYR E 2 301 ? 133.380 138.350 119.060 1.00 61.05  ? 303 TYR E C   1 
ATOM   13176 O O   . TYR E 2 301 ? 132.865 137.276 119.380 1.00 61.05  ? 303 TYR E O   1 
ATOM   13177 C CB  . TYR E 2 301 ? 134.295 140.064 120.638 1.00 61.05  ? 303 TYR E CB  1 
ATOM   13178 C CG  . TYR E 2 301 ? 134.514 139.253 121.896 1.00 61.05  ? 303 TYR E CG  1 
ATOM   13179 C CD1 . TYR E 2 301 ? 134.985 137.949 121.833 1.00 61.05  ? 303 TYR E CD1 1 
ATOM   13180 C CD2 . TYR E 2 301 ? 134.264 139.798 123.147 1.00 61.05  ? 303 TYR E CD2 1 
ATOM   13181 C CE1 . TYR E 2 301 ? 135.190 137.209 122.977 1.00 61.05  ? 303 TYR E CE1 1 
ATOM   13182 C CE2 . TYR E 2 301 ? 134.468 139.065 124.298 1.00 61.05  ? 303 TYR E CE2 1 
ATOM   13183 C CZ  . TYR E 2 301 ? 134.931 137.770 124.207 1.00 61.05  ? 303 TYR E CZ  1 
ATOM   13184 O OH  . TYR E 2 301 ? 135.136 137.031 125.349 1.00 61.05  ? 303 TYR E OH  1 
ATOM   13185 N N   . VAL E 2 302 ? 134.229 138.469 118.046 1.00 63.26  ? 304 VAL E N   1 
ATOM   13186 C CA  . VAL E 2 302 ? 134.654 137.317 117.263 1.00 63.26  ? 304 VAL E CA  1 
ATOM   13187 C C   . VAL E 2 302 ? 135.795 136.612 117.984 1.00 63.26  ? 304 VAL E C   1 
ATOM   13188 O O   . VAL E 2 302 ? 136.525 137.212 118.780 1.00 63.26  ? 304 VAL E O   1 
ATOM   13189 C CB  . VAL E 2 302 ? 135.062 137.751 115.841 1.00 63.26  ? 304 VAL E CB  1 
ATOM   13190 C CG1 . VAL E 2 302 ? 136.453 138.364 115.844 1.00 63.26  ? 304 VAL E CG1 1 
ATOM   13191 C CG2 . VAL E 2 302 ? 134.987 136.577 114.880 1.00 63.26  ? 304 VAL E CG2 1 
ATOM   13192 N N   . LYS E 2 303 ? 135.943 135.322 117.714 1.00 61.05  ? 305 LYS E N   1 
ATOM   13193 C CA  . LYS E 2 303 ? 136.985 134.501 118.314 1.00 61.05  ? 305 LYS E CA  1 
ATOM   13194 C C   . LYS E 2 303 ? 137.892 133.957 117.211 1.00 61.05  ? 305 LYS E C   1 
ATOM   13195 O O   . LYS E 2 303 ? 137.826 134.383 116.056 1.00 61.05  ? 305 LYS E O   1 
ATOM   13196 C CB  . LYS E 2 303 ? 136.369 133.386 119.162 1.00 61.05  ? 305 LYS E CB  1 
ATOM   13197 C CG  . LYS E 2 303 ? 135.173 132.703 118.529 1.00 61.05  ? 305 LYS E CG  1 
ATOM   13198 C CD  . LYS E 2 303 ? 134.544 131.705 119.482 1.00 61.05  ? 305 LYS E CD  1 
ATOM   13199 C CE  . LYS E 2 303 ? 133.946 132.400 120.688 1.00 61.05  ? 305 LYS E CE  1 
ATOM   13200 N NZ  . LYS E 2 303 ? 132.809 133.276 120.303 1.00 61.05  ? 305 LYS E NZ  1 
ATOM   13201 N N   . ALA E 2 304 ? 138.769 133.028 117.583 1.00 62.42  ? 306 ALA E N   1 
ATOM   13202 C CA  . ALA E 2 304 ? 139.676 132.419 116.620 1.00 62.42  ? 306 ALA E CA  1 
ATOM   13203 C C   . ALA E 2 304 ? 139.041 131.252 115.876 1.00 62.42  ? 306 ALA E C   1 
ATOM   13204 O O   . ALA E 2 304 ? 139.282 131.079 114.676 1.00 62.42  ? 306 ALA E O   1 
ATOM   13205 C CB  . ALA E 2 304 ? 140.948 131.946 117.321 1.00 62.42  ? 306 ALA E CB  1 
ATOM   13206 N N   . LEU E 2 305 ? 138.242 130.441 116.572 1.00 66.52  ? 307 LEU E N   1 
ATOM   13207 C CA  . LEU E 2 305 ? 137.674 129.249 115.952 1.00 66.52  ? 307 LEU E CA  1 
ATOM   13208 C C   . LEU E 2 305 ? 136.742 129.613 114.804 1.00 66.52  ? 307 LEU E C   1 
ATOM   13209 O O   . LEU E 2 305 ? 136.830 129.039 113.712 1.00 66.52  ? 307 LEU E O   1 
ATOM   13210 C CB  . LEU E 2 305 ? 136.937 128.418 117.000 1.00 66.52  ? 307 LEU E CB  1 
ATOM   13211 C CG  . LEU E 2 305 ? 136.311 127.122 116.488 1.00 66.52  ? 307 LEU E CG  1 
ATOM   13212 C CD1 . LEU E 2 305 ? 137.391 126.113 116.137 1.00 66.52  ? 307 LEU E CD1 1 
ATOM   13213 C CD2 . LEU E 2 305 ? 135.349 126.553 117.516 1.00 66.52  ? 307 LEU E CD2 1 
ATOM   13214 N N   . ASP E 2 306 ? 135.841 130.570 115.029 1.00 68.48  ? 308 ASP E N   1 
ATOM   13215 C CA  . ASP E 2 306 ? 134.919 130.950 113.966 1.00 68.48  ? 308 ASP E CA  1 
ATOM   13216 C C   . ASP E 2 306 ? 135.638 131.669 112.834 1.00 68.48  ? 308 ASP E C   1 
ATOM   13217 O O   . ASP E 2 306 ? 135.247 131.526 111.673 1.00 68.48  ? 308 ASP E O   1 
ATOM   13218 C CB  . ASP E 2 306 ? 133.783 131.810 114.522 1.00 68.48  ? 308 ASP E CB  1 
ATOM   13219 C CG  . ASP E 2 306 ? 134.278 133.054 115.224 1.00 68.48  ? 308 ASP E CG  1 
ATOM   13220 O OD1 . ASP E 2 306 ? 135.508 133.243 115.307 1.00 68.48  ? 308 ASP E OD1 1 
ATOM   13221 O OD2 . ASP E 2 306 ? 133.435 133.843 115.699 1.00 68.48  ? 308 ASP E OD2 1 
ATOM   13222 N N   . VAL E 2 307 ? 136.688 132.433 113.143 1.00 64.83  ? 309 VAL E N   1 
ATOM   13223 C CA  . VAL E 2 307 ? 137.472 133.073 112.088 1.00 64.83  ? 309 VAL E CA  1 
ATOM   13224 C C   . VAL E 2 307 ? 138.121 132.018 111.200 1.00 64.83  ? 309 VAL E C   1 
ATOM   13225 O O   . VAL E 2 307 ? 138.073 132.101 109.967 1.00 64.83  ? 309 VAL E O   1 
ATOM   13226 C CB  . VAL E 2 307 ? 138.518 134.025 112.696 1.00 64.83  ? 309 VAL E CB  1 
ATOM   13227 C CG1 . VAL E 2 307 ? 139.726 134.152 111.781 1.00 64.83  ? 309 VAL E CG1 1 
ATOM   13228 C CG2 . VAL E 2 307 ? 137.903 135.389 112.946 1.00 64.83  ? 309 VAL E CG2 1 
ATOM   13229 N N   . TRP E 2 308 ? 138.718 130.998 111.817 1.00 64.68  ? 310 TRP E N   1 
ATOM   13230 C CA  . TRP E 2 308 ? 139.323 129.918 111.045 1.00 64.68  ? 310 TRP E CA  1 
ATOM   13231 C C   . TRP E 2 308 ? 138.278 129.181 110.218 1.00 64.68  ? 310 TRP E C   1 
ATOM   13232 O O   . TRP E 2 308 ? 138.506 128.875 109.039 1.00 64.68  ? 310 TRP E O   1 
ATOM   13233 C CB  . TRP E 2 308 ? 140.043 128.955 111.989 1.00 64.68  ? 310 TRP E CB  1 
ATOM   13234 C CG  . TRP E 2 308 ? 140.375 127.630 111.385 1.00 64.68  ? 310 TRP E CG  1 
ATOM   13235 C CD1 . TRP E 2 308 ? 139.572 126.530 111.328 1.00 64.68  ? 310 TRP E CD1 1 
ATOM   13236 C CD2 . TRP E 2 308 ? 141.609 127.257 110.769 1.00 64.68  ? 310 TRP E CD2 1 
ATOM   13237 N NE1 . TRP E 2 308 ? 140.226 125.499 110.705 1.00 64.68  ? 310 TRP E NE1 1 
ATOM   13238 C CE2 . TRP E 2 308 ? 141.480 125.920 110.352 1.00 64.68  ? 310 TRP E CE2 1 
ATOM   13239 C CE3 . TRP E 2 308 ? 142.811 127.927 110.524 1.00 64.68  ? 310 TRP E CE3 1 
ATOM   13240 C CZ2 . TRP E 2 308 ? 142.505 125.241 109.706 1.00 64.68  ? 310 TRP E CZ2 1 
ATOM   13241 C CZ3 . TRP E 2 308 ? 143.827 127.250 109.882 1.00 64.68  ? 310 TRP E CZ3 1 
ATOM   13242 C CH2 . TRP E 2 308 ? 143.668 125.921 109.480 1.00 64.68  ? 310 TRP E CH2 1 
ATOM   13243 N N   . LEU E 2 309 ? 137.124 128.889 110.820 1.00 63.78  ? 311 LEU E N   1 
ATOM   13244 C CA  . LEU E 2 309 ? 136.087 128.152 110.107 1.00 63.78  ? 311 LEU E CA  1 
ATOM   13245 C C   . LEU E 2 309 ? 135.557 128.951 108.924 1.00 63.78  ? 311 LEU E C   1 
ATOM   13246 O O   . LEU E 2 309 ? 135.355 128.400 107.837 1.00 63.78  ? 311 LEU E O   1 
ATOM   13247 C CB  . LEU E 2 309 ? 134.954 127.784 111.063 1.00 63.78  ? 311 LEU E CB  1 
ATOM   13248 C CG  . LEU E 2 309 ? 134.965 126.347 111.591 1.00 63.78  ? 311 LEU E CG  1 
ATOM   13249 C CD1 . LEU E 2 309 ? 134.745 125.358 110.462 1.00 63.78  ? 311 LEU E CD1 1 
ATOM   13250 C CD2 . LEU E 2 309 ? 136.261 126.044 112.323 1.00 63.78  ? 311 LEU E CD2 1 
ATOM   13251 N N   . ILE E 2 310 ? 135.336 130.254 109.109 1.00 64.77  ? 312 ILE E N   1 
ATOM   13252 C CA  . ILE E 2 310 ? 134.818 131.069 108.018 1.00 64.77  ? 312 ILE E CA  1 
ATOM   13253 C C   . ILE E 2 310 ? 135.875 131.261 106.937 1.00 64.77  ? 312 ILE E C   1 
ATOM   13254 O O   . ILE E 2 310 ? 135.542 131.337 105.751 1.00 64.77  ? 312 ILE E O   1 
ATOM   13255 C CB  . ILE E 2 310 ? 134.274 132.411 108.546 1.00 64.77  ? 312 ILE E CB  1 
ATOM   13256 C CG1 . ILE E 2 310 ? 133.286 133.014 107.546 1.00 64.77  ? 312 ILE E CG1 1 
ATOM   13257 C CG2 . ILE E 2 310 ? 135.395 133.393 108.837 1.00 64.77  ? 312 ILE E CG2 1 
ATOM   13258 C CD1 . ILE E 2 310 ? 132.683 134.326 107.995 1.00 64.77  ? 312 ILE E CD1 1 
ATOM   13259 N N   . ALA E 2 311 ? 137.156 131.324 107.309 1.00 62.58  ? 313 ALA E N   1 
ATOM   13260 C CA  . ALA E 2 311 ? 138.199 131.403 106.292 1.00 62.58  ? 313 ALA E CA  1 
ATOM   13261 C C   . ALA E 2 311 ? 138.250 130.130 105.457 1.00 62.58  ? 313 ALA E C   1 
ATOM   13262 O O   . ALA E 2 311 ? 138.363 130.189 104.226 1.00 62.58  ? 313 ALA E O   1 
ATOM   13263 C CB  . ALA E 2 311 ? 139.552 131.675 106.945 1.00 62.58  ? 313 ALA E CB  1 
ATOM   13264 N N   . CYS E 2 312 ? 138.155 128.968 106.106 1.00 66.25  ? 314 CYS E N   1 
ATOM   13265 C CA  . CYS E 2 312 ? 138.134 127.715 105.357 1.00 66.25  ? 314 CYS E CA  1 
ATOM   13266 C C   . CYS E 2 312 ? 136.887 127.616 104.481 1.00 66.25  ? 314 CYS E C   1 
ATOM   13267 O O   . CYS E 2 312 ? 136.947 127.120 103.346 1.00 66.25  ? 314 CYS E O   1 
ATOM   13268 C CB  . CYS E 2 312 ? 138.222 126.532 106.319 1.00 66.25  ? 314 CYS E CB  1 
ATOM   13269 S SG  . CYS E 2 312 ? 139.835 126.333 107.104 1.00 66.25  ? 314 CYS E SG  1 
ATOM   13270 N N   . LEU E 2 313 ? 135.744 128.076 104.996 1.00 62.65  ? 315 LEU E N   1 
ATOM   13271 C CA  . LEU E 2 313 ? 134.519 128.073 104.204 1.00 62.65  ? 315 LEU E CA  1 
ATOM   13272 C C   . LEU E 2 313 ? 134.651 128.974 102.984 1.00 62.65  ? 315 LEU E C   1 
ATOM   13273 O O   . LEU E 2 313 ? 134.205 128.617 101.888 1.00 62.65  ? 315 LEU E O   1 
ATOM   13274 C CB  . LEU E 2 313 ? 133.339 128.509 105.069 1.00 62.65  ? 315 LEU E CB  1 
ATOM   13275 C CG  . LEU E 2 313 ? 131.950 128.218 104.506 1.00 62.65  ? 315 LEU E CG  1 
ATOM   13276 C CD1 . LEU E 2 313 ? 131.787 126.730 104.281 1.00 62.65  ? 315 LEU E CD1 1 
ATOM   13277 C CD2 . LEU E 2 313 ? 130.874 128.738 105.441 1.00 62.65  ? 315 LEU E CD2 1 
ATOM   13278 N N   . LEU E 2 314 ? 135.263 130.147 103.154 1.00 62.34  ? 316 LEU E N   1 
ATOM   13279 C CA  . LEU E 2 314 ? 135.502 131.024 102.015 1.00 62.34  ? 316 LEU E CA  1 
ATOM   13280 C C   . LEU E 2 314 ? 136.476 130.403 101.025 1.00 62.34  ? 316 LEU E C   1 
ATOM   13281 O O   . LEU E 2 314 ? 136.353 130.633 99.821  1.00 62.34  ? 316 LEU E O   1 
ATOM   13282 C CB  . LEU E 2 314 ? 136.017 132.384 102.485 1.00 62.34  ? 316 LEU E CB  1 
ATOM   13283 C CG  . LEU E 2 314 ? 134.989 133.517 102.514 1.00 62.34  ? 316 LEU E CG  1 
ATOM   13284 C CD1 . LEU E 2 314 ? 133.766 133.127 103.324 1.00 62.34  ? 316 LEU E CD1 1 
ATOM   13285 C CD2 . LEU E 2 314 ? 135.609 134.795 103.054 1.00 62.34  ? 316 LEU E CD2 1 
ATOM   13286 N N   . PHE E 2 315 ? 137.448 129.625 101.501 1.00 66.35  ? 317 PHE E N   1 
ATOM   13287 C CA  . PHE E 2 315 ? 138.340 128.935 100.572 1.00 66.35  ? 317 PHE E CA  1 
ATOM   13288 C C   . PHE E 2 315 ? 137.590 127.891 99.750  1.00 66.35  ? 317 PHE E C   1 
ATOM   13289 O O   . PHE E 2 315 ? 137.803 127.774 98.534  1.00 66.35  ? 317 PHE E O   1 
ATOM   13290 C CB  . PHE E 2 315 ? 139.502 128.300 101.331 1.00 66.35  ? 317 PHE E CB  1 
ATOM   13291 C CG  . PHE E 2 315 ? 140.638 129.245 101.586 1.00 66.35  ? 317 PHE E CG  1 
ATOM   13292 C CD1 . PHE E 2 315 ? 140.656 130.497 100.995 1.00 66.35  ? 317 PHE E CD1 1 
ATOM   13293 C CD2 . PHE E 2 315 ? 141.682 128.888 102.416 1.00 66.35  ? 317 PHE E CD2 1 
ATOM   13294 C CE1 . PHE E 2 315 ? 141.698 131.372 101.225 1.00 66.35  ? 317 PHE E CE1 1 
ATOM   13295 C CE2 . PHE E 2 315 ? 142.728 129.758 102.651 1.00 66.35  ? 317 PHE E CE2 1 
ATOM   13296 C CZ  . PHE E 2 315 ? 142.735 131.002 102.055 1.00 66.35  ? 317 PHE E CZ  1 
ATOM   13297 N N   . GLY E 2 316 ? 136.708 127.124 100.391 1.00 66.66  ? 318 GLY E N   1 
ATOM   13298 C CA  . GLY E 2 316 ? 135.877 126.194 99.637  1.00 66.66  ? 318 GLY E CA  1 
ATOM   13299 C C   . GLY E 2 316 ? 134.975 126.906 98.644  1.00 66.66  ? 318 GLY E C   1 
ATOM   13300 O O   . GLY E 2 316 ? 134.798 126.456 97.504  1.00 66.66  ? 318 GLY E O   1 
ATOM   13301 N N   . PHE E 2 317 ? 134.407 128.037 99.061  1.00 68.69  ? 319 PHE E N   1 
ATOM   13302 C CA  . PHE E 2 317 ? 133.604 128.855 98.160  1.00 68.69  ? 319 PHE E CA  1 
ATOM   13303 C C   . PHE E 2 317 ? 134.429 129.333 96.973  1.00 68.69  ? 319 PHE E C   1 
ATOM   13304 O O   . PHE E 2 317 ? 133.940 129.365 95.837  1.00 68.69  ? 319 PHE E O   1 
ATOM   13305 C CB  . PHE E 2 317 ? 133.035 130.047 98.926  1.00 68.69  ? 319 PHE E CB  1 
ATOM   13306 C CG  . PHE E 2 317 ? 131.615 130.358 98.590  1.00 68.69  ? 319 PHE E CG  1 
ATOM   13307 C CD1 . PHE E 2 317 ? 130.581 129.679 99.207  1.00 68.69  ? 319 PHE E CD1 1 
ATOM   13308 C CD2 . PHE E 2 317 ? 131.312 131.336 97.662  1.00 68.69  ? 319 PHE E CD2 1 
ATOM   13309 C CE1 . PHE E 2 317 ? 129.272 129.968 98.903  1.00 68.69  ? 319 PHE E CE1 1 
ATOM   13310 C CE2 . PHE E 2 317 ? 130.004 131.628 97.352  1.00 68.69  ? 319 PHE E CE2 1 
ATOM   13311 C CZ  . PHE E 2 317 ? 128.982 130.943 97.974  1.00 68.69  ? 319 PHE E CZ  1 
ATOM   13312 N N   . ALA E 2 318 ? 135.679 129.728 97.226  1.00 68.98  ? 320 ALA E N   1 
ATOM   13313 C CA  . ALA E 2 318 ? 136.567 130.164 96.157  1.00 68.98  ? 320 ALA E CA  1 
ATOM   13314 C C   . ALA E 2 318 ? 136.831 129.034 95.177  1.00 68.98  ? 320 ALA E C   1 
ATOM   13315 O O   . ALA E 2 318 ? 136.864 129.252 93.962  1.00 68.98  ? 320 ALA E O   1 
ATOM   13316 C CB  . ALA E 2 318 ? 137.877 130.689 96.740  1.00 68.98  ? 320 ALA E CB  1 
ATOM   13317 N N   . SER E 2 319 ? 137.022 127.818 95.688  1.00 71.69  ? 321 SER E N   1 
ATOM   13318 C CA  . SER E 2 319 ? 137.176 126.671 94.799  1.00 71.69  ? 321 SER E CA  1 
ATOM   13319 C C   . SER E 2 319 ? 135.939 126.484 93.929  1.00 71.69  ? 321 SER E C   1 
ATOM   13320 O O   . SER E 2 319 ? 136.046 126.241 92.717  1.00 71.69  ? 321 SER E O   1 
ATOM   13321 C CB  . SER E 2 319 ? 137.455 125.409 95.613  1.00 71.69  ? 321 SER E CB  1 
ATOM   13322 O OG  . SER E 2 319 ? 137.052 124.250 94.904  1.00 71.69  ? 321 SER E OG  1 
ATOM   13323 N N   . LEU E 2 320 ? 134.753 126.605 94.529  1.00 70.31  ? 322 LEU E N   1 
ATOM   13324 C CA  . LEU E 2 320 ? 133.521 126.422 93.763  1.00 70.31  ? 322 LEU E CA  1 
ATOM   13325 C C   . LEU E 2 320 ? 133.386 127.477 92.667  1.00 70.31  ? 322 LEU E C   1 
ATOM   13326 O O   . LEU E 2 320 ? 133.055 127.158 91.517  1.00 70.31  ? 322 LEU E O   1 
ATOM   13327 C CB  . LEU E 2 320 ? 132.313 126.454 94.701  1.00 70.31  ? 322 LEU E CB  1 
ATOM   13328 C CG  . LEU E 2 320 ? 131.146 125.525 94.351  1.00 70.31  ? 322 LEU E CG  1 
ATOM   13329 C CD1 . LEU E 2 320 ? 130.386 126.007 93.126  1.00 70.31  ? 322 LEU E CD1 1 
ATOM   13330 C CD2 . LEU E 2 320 ? 131.649 124.107 94.140  1.00 70.31  ? 322 LEU E CD2 1 
ATOM   13331 N N   . VAL E 2 321 ? 133.644 128.745 93.000  1.00 71.73  ? 323 VAL E N   1 
ATOM   13332 C CA  . VAL E 2 321 ? 133.477 129.788 91.991  1.00 71.73  ? 323 VAL E CA  1 
ATOM   13333 C C   . VAL E 2 321 ? 134.566 129.673 90.930  1.00 71.73  ? 323 VAL E C   1 
ATOM   13334 O O   . VAL E 2 321 ? 134.333 129.989 89.758  1.00 71.73  ? 323 VAL E O   1 
ATOM   13335 C CB  . VAL E 2 321 ? 133.446 131.195 92.624  1.00 71.73  ? 323 VAL E CB  1 
ATOM   13336 C CG1 . VAL E 2 321 ? 134.564 131.376 93.609  1.00 71.73  ? 323 VAL E CG1 1 
ATOM   13337 C CG2 . VAL E 2 321 ? 133.484 132.285 91.558  1.00 71.73  ? 323 VAL E CG2 1 
ATOM   13338 N N   . GLU E 2 322 ? 135.761 129.208 91.306  1.00 76.16  ? 324 GLU E N   1 
ATOM   13339 C CA  . GLU E 2 322 ? 136.790 128.959 90.305  1.00 76.16  ? 324 GLU E CA  1 
ATOM   13340 C C   . GLU E 2 322 ? 136.339 127.894 89.321  1.00 76.16  ? 324 GLU E C   1 
ATOM   13341 O O   . GLU E 2 322 ? 136.550 128.027 88.109  1.00 76.16  ? 324 GLU E O   1 
ATOM   13342 C CB  . GLU E 2 322 ? 138.099 128.534 90.970  1.00 76.16  ? 324 GLU E CB  1 
ATOM   13343 C CG  . GLU E 2 322 ? 139.255 128.365 89.989  1.00 76.16  ? 324 GLU E CG  1 
ATOM   13344 C CD  . GLU E 2 322 ? 139.408 126.941 89.469  1.00 76.16  ? 324 GLU E CD  1 
ATOM   13345 O OE1 . GLU E 2 322 ? 138.509 126.106 89.700  1.00 76.16  ? 324 GLU E OE1 1 
ATOM   13346 O OE2 . GLU E 2 322 ? 140.432 126.655 88.815  1.00 76.16  ? 324 GLU E OE2 1 
ATOM   13347 N N   . TYR E 2 323 ? 135.734 126.815 89.822  1.00 80.40  ? 325 TYR E N   1 
ATOM   13348 C CA  . TYR E 2 323 ? 135.215 125.808 88.906  1.00 80.40  ? 325 TYR E CA  1 
ATOM   13349 C C   . TYR E 2 323 ? 134.121 126.385 88.018  1.00 80.40  ? 325 TYR E C   1 
ATOM   13350 O O   . TYR E 2 323 ? 134.027 126.037 86.836  1.00 80.40  ? 325 TYR E O   1 
ATOM   13351 C CB  . TYR E 2 323 ? 134.702 124.580 89.660  1.00 80.40  ? 325 TYR E CB  1 
ATOM   13352 C CG  . TYR E 2 323 ? 133.883 123.692 88.757  1.00 80.40  ? 325 TYR E CG  1 
ATOM   13353 C CD1 . TYR E 2 323 ? 132.513 123.882 88.620  1.00 80.40  ? 325 TYR E CD1 1 
ATOM   13354 C CD2 . TYR E 2 323 ? 134.494 122.733 87.963  1.00 80.40  ? 325 TYR E CD2 1 
ATOM   13355 C CE1 . TYR E 2 323 ? 131.773 123.108 87.773  1.00 80.40  ? 325 TYR E CE1 1 
ATOM   13356 C CE2 . TYR E 2 323 ? 133.755 121.952 87.107  1.00 80.40  ? 325 TYR E CE2 1 
ATOM   13357 C CZ  . TYR E 2 323 ? 132.396 122.147 87.020  1.00 80.40  ? 325 TYR E CZ  1 
ATOM   13358 O OH  . TYR E 2 323 ? 131.646 121.384 86.174  1.00 80.40  ? 325 TYR E OH  1 
ATOM   13359 N N   . ALA E 2 324 ? 133.263 127.239 88.577  1.00 74.95  ? 326 ALA E N   1 
ATOM   13360 C CA  . ALA E 2 324 ? 132.226 127.865 87.761  1.00 74.95  ? 326 ALA E CA  1 
ATOM   13361 C C   . ALA E 2 324 ? 132.839 128.707 86.647  1.00 74.95  ? 326 ALA E C   1 
ATOM   13362 O O   . ALA E 2 324 ? 132.354 128.698 85.508  1.00 74.95  ? 326 ALA E O   1 
ATOM   13363 C CB  . ALA E 2 324 ? 131.308 128.716 88.636  1.00 74.95  ? 326 ALA E CB  1 
ATOM   13364 N N   . VAL E 2 325 ? 133.906 129.444 86.963  1.00 74.37  ? 327 VAL E N   1 
ATOM   13365 C CA  . VAL E 2 325 ? 134.608 130.237 85.955  1.00 74.37  ? 327 VAL E CA  1 
ATOM   13366 C C   . VAL E 2 325 ? 135.208 129.331 84.889  1.00 74.37  ? 327 VAL E C   1 
ATOM   13367 O O   . VAL E 2 325 ? 135.144 129.626 83.689  1.00 74.37  ? 327 VAL E O   1 
ATOM   13368 C CB  . VAL E 2 325 ? 135.682 131.116 86.621  1.00 74.37  ? 327 VAL E CB  1 
ATOM   13369 C CG1 . VAL E 2 325 ? 136.652 131.656 85.582  1.00 74.37  ? 327 VAL E CG1 1 
ATOM   13370 C CG2 . VAL E 2 325 ? 135.031 132.255 87.390  1.00 74.37  ? 327 VAL E CG2 1 
ATOM   13371 N N   . VAL E 2 326 ? 135.802 128.214 85.311  1.00 79.31  ? 328 VAL E N   1 
ATOM   13372 C CA  . VAL E 2 326 ? 136.357 127.261 84.354  1.00 79.31  ? 328 VAL E CA  1 
ATOM   13373 C C   . VAL E 2 326 ? 135.267 126.752 83.420  1.00 79.31  ? 328 VAL E C   1 
ATOM   13374 O O   . VAL E 2 326 ? 135.455 126.677 82.199  1.00 79.31  ? 328 VAL E O   1 
ATOM   13375 C CB  . VAL E 2 326 ? 137.053 126.103 85.097  1.00 79.31  ? 328 VAL E CB  1 
ATOM   13376 C CG1 . VAL E 2 326 ? 137.172 124.880 84.200  1.00 79.31  ? 328 VAL E CG1 1 
ATOM   13377 C CG2 . VAL E 2 326 ? 138.419 126.538 85.605  1.00 79.31  ? 328 VAL E CG2 1 
ATOM   13378 N N   . GLN E 2 327 ? 134.105 126.410 83.977  1.00 78.61  ? 329 GLN E N   1 
ATOM   13379 C CA  . GLN E 2 327 ? 133.029 125.849 83.169  1.00 78.61  ? 329 GLN E CA  1 
ATOM   13380 C C   . GLN E 2 327 ? 132.487 126.886 82.192  1.00 78.61  ? 329 GLN E C   1 
ATOM   13381 O O   . GLN E 2 327 ? 132.226 126.566 81.026  1.00 78.61  ? 329 GLN E O   1 
ATOM   13382 C CB  . GLN E 2 327 ? 131.944 125.278 84.096  1.00 78.61  ? 329 GLN E CB  1 
ATOM   13383 C CG  . GLN E 2 327 ? 130.733 124.555 83.457  1.00 78.61  ? 329 GLN E CG  1 
ATOM   13384 C CD  . GLN E 2 327 ? 129.777 125.418 82.644  1.00 78.61  ? 329 GLN E CD  1 
ATOM   13385 O OE1 . GLN E 2 327 ? 129.836 126.646 82.658  1.00 78.61  ? 329 GLN E OE1 1 
ATOM   13386 N NE2 . GLN E 2 327 ? 128.890 124.758 81.910  1.00 78.61  ? 329 GLN E NE2 1 
ATOM   13387 N N   . VAL E 2 328 ? 132.302 128.131 82.645  1.00 77.03  ? 330 VAL E N   1 
ATOM   13388 C CA  . VAL E 2 328 ? 131.777 129.155 81.743  1.00 77.03  ? 330 VAL E CA  1 
ATOM   13389 C C   . VAL E 2 328 ? 132.796 129.499 80.660  1.00 77.03  ? 330 VAL E C   1 
ATOM   13390 O O   . VAL E 2 328 ? 132.418 129.795 79.520  1.00 77.03  ? 330 VAL E O   1 
ATOM   13391 C CB  . VAL E 2 328 ? 131.322 130.405 82.527  1.00 77.03  ? 330 VAL E CB  1 
ATOM   13392 C CG1 . VAL E 2 328 ? 132.486 131.084 83.216  1.00 77.03  ? 330 VAL E CG1 1 
ATOM   13393 C CG2 . VAL E 2 328 ? 130.601 131.383 81.607  1.00 77.03  ? 330 VAL E CG2 1 
ATOM   13394 N N   . MET E 2 329 ? 134.092 129.465 80.983  1.00 76.35  ? 331 MET E N   1 
ATOM   13395 C CA  . MET E 2 329 ? 135.108 129.655 79.954  1.00 76.35  ? 331 MET E CA  1 
ATOM   13396 C C   . MET E 2 329 ? 135.081 128.518 78.941  1.00 76.35  ? 331 MET E C   1 
ATOM   13397 O O   . MET E 2 329 ? 135.227 128.750 77.735  1.00 76.35  ? 331 MET E O   1 
ATOM   13398 C CB  . MET E 2 329 ? 136.492 129.771 80.594  1.00 76.35  ? 331 MET E CB  1 
ATOM   13399 N N   . LEU E 2 330 ? 134.901 127.283 79.414  1.00 80.65  ? 332 LEU E N   1 
ATOM   13400 C CA  . LEU E 2 330 ? 134.817 126.145 78.505  1.00 80.65  ? 332 LEU E CA  1 
ATOM   13401 C C   . LEU E 2 330 ? 133.608 126.262 77.586  1.00 80.65  ? 332 LEU E C   1 
ATOM   13402 O O   . LEU E 2 330 ? 133.698 125.964 76.389  1.00 80.65  ? 332 LEU E O   1 
ATOM   13403 C CB  . LEU E 2 330 ? 134.763 124.841 79.301  1.00 80.65  ? 332 LEU E CB  1 
ATOM   13404 N N   . ASN E 2 331 ? 132.471 126.693 78.124  1.00 81.71  ? 333 ASN E N   1 
ATOM   13405 C CA  . ASN E 2 331 ? 131.270 126.873 77.316  1.00 81.71  ? 333 ASN E CA  1 
ATOM   13406 C C   . ASN E 2 331 ? 131.005 128.349 77.040  1.00 81.71  ? 333 ASN E C   1 
ATOM   13407 O O   . ASN E 2 331 ? 130.505 128.712 75.975  1.00 81.71  ? 333 ASN E O   1 
ATOM   13408 C CB  . ASN E 2 331 ? 130.059 126.242 78.005  1.00 81.71  ? 333 ASN E CB  1 
ATOM   13409 C CG  . ASN E 2 331 ? 130.203 124.746 78.178  1.00 81.71  ? 333 ASN E CG  1 
ATOM   13410 O OD1 . ASN E 2 331 ? 130.058 124.221 79.281  1.00 81.71  ? 333 ASN E OD1 1 
ATOM   13411 N ND2 . ASN E 2 331 ? 130.498 124.050 77.087  1.00 81.71  ? 333 ASN E ND2 1 
ATOM   13412 N N   . ILE E 2 649 ? 140.681 127.999 73.038  1.00 83.40  ? 444 ILE E N   1 
ATOM   13413 C CA  . ILE E 2 649 ? 139.822 128.224 74.196  1.00 83.40  ? 444 ILE E CA  1 
ATOM   13414 C C   . ILE E 2 649 ? 139.981 127.134 75.271  1.00 83.40  ? 444 ILE E C   1 
ATOM   13415 O O   . ILE E 2 649 ? 140.103 127.468 76.451  1.00 83.40  ? 444 ILE E O   1 
ATOM   13416 C CB  . ILE E 2 649 ? 138.342 128.364 73.770  1.00 83.40  ? 444 ILE E CB  1 
ATOM   13417 N N   . PRO E 2 650 ? 139.971 125.844 74.893  1.00 82.71  ? 445 PRO E N   1 
ATOM   13418 C CA  . PRO E 2 650 ? 140.237 124.813 75.912  1.00 82.71  ? 445 PRO E CA  1 
ATOM   13419 C C   . PRO E 2 650 ? 141.586 124.976 76.586  1.00 82.71  ? 445 PRO E C   1 
ATOM   13420 O O   . PRO E 2 650 ? 141.711 124.707 77.788  1.00 82.71  ? 445 PRO E O   1 
ATOM   13421 C CB  . PRO E 2 650 ? 140.151 123.503 75.115  1.00 82.71  ? 445 PRO E CB  1 
ATOM   13422 C CG  . PRO E 2 650 ? 139.271 123.822 73.972  1.00 82.71  ? 445 PRO E CG  1 
ATOM   13423 C CD  . PRO E 2 650 ? 139.621 125.228 73.598  1.00 82.71  ? 445 PRO E CD  1 
ATOM   13424 N N   . THR E 2 651 ? 142.606 125.410 75.842  1.00 78.27  ? 446 THR E N   1 
ATOM   13425 C CA  . THR E 2 651 ? 143.902 125.682 76.454  1.00 78.27  ? 446 THR E CA  1 
ATOM   13426 C C   . THR E 2 651 ? 143.811 126.839 77.440  1.00 78.27  ? 446 THR E C   1 
ATOM   13427 O O   . THR E 2 651 ? 144.447 126.810 78.500  1.00 78.27  ? 446 THR E O   1 
ATOM   13428 C CB  . THR E 2 651 ? 144.945 125.977 75.377  1.00 78.27  ? 446 THR E CB  1 
ATOM   13429 N N   . ALA E 2 652 ? 143.033 127.872 77.103  1.00 78.61  ? 447 ALA E N   1 
ATOM   13430 C CA  . ALA E 2 652 ? 142.859 128.997 78.016  1.00 78.61  ? 447 ALA E CA  1 
ATOM   13431 C C   . ALA E 2 652 ? 142.180 128.560 79.307  1.00 78.61  ? 447 ALA E C   1 
ATOM   13432 O O   . ALA E 2 652 ? 142.592 128.963 80.401  1.00 78.61  ? 447 ALA E O   1 
ATOM   13433 C CB  . ALA E 2 652 ? 142.058 130.107 77.336  1.00 78.61  ? 447 ALA E CB  1 
ATOM   13434 N N   . ALA E 2 653 ? 141.134 127.737 79.200  1.00 78.50  ? 448 ALA E N   1 
ATOM   13435 C CA  . ALA E 2 653 ? 140.484 127.216 80.398  1.00 78.50  ? 448 ALA E CA  1 
ATOM   13436 C C   . ALA E 2 653 ? 141.428 126.317 81.186  1.00 78.50  ? 448 ALA E C   1 
ATOM   13437 O O   . ALA E 2 653 ? 141.492 126.399 82.418  1.00 78.50  ? 448 ALA E O   1 
ATOM   13438 C CB  . ALA E 2 653 ? 139.212 126.459 80.017  1.00 78.50  ? 448 ALA E CB  1 
ATOM   13439 N N   . LYS E 2 654 ? 142.171 125.455 80.489  1.00 76.12  ? 449 LYS E N   1 
ATOM   13440 C CA  . LYS E 2 654 ? 143.128 124.586 81.165  1.00 76.12  ? 449 LYS E CA  1 
ATOM   13441 C C   . LYS E 2 654 ? 144.230 125.396 81.832  1.00 76.12  ? 449 LYS E C   1 
ATOM   13442 O O   . LYS E 2 654 ? 144.680 125.057 82.932  1.00 76.12  ? 449 LYS E O   1 
ATOM   13443 C CB  . LYS E 2 654 ? 143.720 123.584 80.175  1.00 76.12  ? 449 LYS E CB  1 
ATOM   13444 N N   . ARG E 2 655 ? 144.687 126.466 81.176  1.00 79.70  ? 450 ARG E N   1 
ATOM   13445 C CA  . ARG E 2 655 ? 145.715 127.312 81.773  1.00 79.70  ? 450 ARG E CA  1 
ATOM   13446 C C   . ARG E 2 655 ? 145.214 127.970 83.052  1.00 79.70  ? 450 ARG E C   1 
ATOM   13447 O O   . ARG E 2 655 ? 145.932 128.015 84.058  1.00 79.70  ? 450 ARG E O   1 
ATOM   13448 C CB  . ARG E 2 655 ? 146.173 128.370 80.769  1.00 79.70  ? 450 ARG E CB  1 
ATOM   13449 N N   . ILE E 2 656 ? 143.980 128.480 83.037  1.00 80.46  ? 451 ILE E N   1 
ATOM   13450 C CA  . ILE E 2 656 ? 143.415 129.099 84.234  1.00 80.46  ? 451 ILE E CA  1 
ATOM   13451 C C   . ILE E 2 656 ? 143.246 128.066 85.339  1.00 80.46  ? 451 ILE E C   1 
ATOM   13452 O O   . ILE E 2 656 ? 143.523 128.339 86.515  1.00 80.46  ? 451 ILE E O   1 
ATOM   13453 C CB  . ILE E 2 656 ? 142.082 129.794 83.900  1.00 80.46  ? 451 ILE E CB  1 
ATOM   13454 N N   . ASP E 2 657 ? 142.783 126.865 84.981  1.00 83.96  ? 452 ASP E N   1 
ATOM   13455 C CA  . ASP E 2 657 ? 142.614 125.810 85.974  1.00 83.96  ? 452 ASP E CA  1 
ATOM   13456 C C   . ASP E 2 657 ? 143.947 125.428 86.604  1.00 83.96  ? 452 ASP E C   1 
ATOM   13457 O O   . ASP E 2 657 ? 144.039 125.265 87.826  1.00 83.96  ? 452 ASP E O   1 
ATOM   13458 C CB  . ASP E 2 657 ? 141.954 124.591 85.332  1.00 83.96  ? 452 ASP E CB  1 
ATOM   13459 C CG  . ASP E 2 657 ? 141.215 123.729 86.337  1.00 83.96  ? 452 ASP E CG  1 
ATOM   13460 O OD1 . ASP E 2 657 ? 141.745 123.516 87.447  1.00 83.96  ? 452 ASP E OD1 1 
ATOM   13461 O OD2 . ASP E 2 657 ? 140.101 123.263 86.014  1.00 83.96  ? 452 ASP E OD2 1 
ATOM   13462 N N   . LEU E 2 658 ? 144.994 125.289 85.787  1.00 77.74  ? 453 LEU E N   1 
ATOM   13463 C CA  . LEU E 2 658 ? 146.312 124.958 86.318  1.00 77.74  ? 453 LEU E CA  1 
ATOM   13464 C C   . LEU E 2 658 ? 146.853 126.079 87.196  1.00 77.74  ? 453 LEU E C   1 
ATOM   13465 O O   . LEU E 2 658 ? 147.438 125.820 88.255  1.00 77.74  ? 453 LEU E O   1 
ATOM   13466 C CB  . LEU E 2 658 ? 147.277 124.660 85.171  1.00 77.74  ? 453 LEU E CB  1 
ATOM   13467 N N   . TYR E 2 659 ? 146.666 127.333 86.775  1.00 77.71  ? 454 TYR E N   1 
ATOM   13468 C CA  . TYR E 2 659 ? 147.132 128.456 87.578  1.00 77.71  ? 454 TYR E CA  1 
ATOM   13469 C C   . TYR E 2 659 ? 146.441 128.485 88.934  1.00 77.71  ? 454 TYR E C   1 
ATOM   13470 O O   . TYR E 2 659 ? 147.089 128.693 89.964  1.00 77.71  ? 454 TYR E O   1 
ATOM   13471 C CB  . TYR E 2 659 ? 146.901 129.769 86.830  1.00 77.71  ? 454 TYR E CB  1 
ATOM   13472 N N   . ALA E 2 660 ? 145.125 128.266 88.956  1.00 77.84  ? 455 ALA E N   1 
ATOM   13473 C CA  . ALA E 2 660 ? 144.405 128.254 90.225  1.00 77.84  ? 455 ALA E CA  1 
ATOM   13474 C C   . ALA E 2 660 ? 144.817 127.068 91.090  1.00 77.84  ? 455 ALA E C   1 
ATOM   13475 O O   . ALA E 2 660 ? 144.960 127.204 92.311  1.00 77.84  ? 455 ALA E O   1 
ATOM   13476 C CB  . ALA E 2 660 ? 142.899 128.242 89.975  1.00 77.84  ? 455 ALA E CB  1 
ATOM   13477 N N   . ARG E 2 661 ? 145.002 125.894 90.479  1.00 77.70  ? 456 ARG E N   1 
ATOM   13478 C CA  . ARG E 2 661 ? 145.416 124.716 91.231  1.00 77.70  ? 456 ARG E CA  1 
ATOM   13479 C C   . ARG E 2 661 ? 146.823 124.856 91.789  1.00 77.70  ? 456 ARG E C   1 
ATOM   13480 O O   . ARG E 2 661 ? 147.152 124.198 92.781  1.00 77.70  ? 456 ARG E O   1 
ATOM   13481 C CB  . ARG E 2 661 ? 145.328 123.470 90.348  1.00 77.70  ? 456 ARG E CB  1 
ATOM   13482 N N   . ALA E 2 662 ? 147.664 125.680 91.165  1.00 78.34  ? 457 ALA E N   1 
ATOM   13483 C CA  . ALA E 2 662 ? 148.978 125.953 91.734  1.00 78.34  ? 457 ALA E CA  1 
ATOM   13484 C C   . ALA E 2 662 ? 148.927 127.064 92.776  1.00 78.34  ? 457 ALA E C   1 
ATOM   13485 O O   . ALA E 2 662 ? 149.712 127.046 93.729  1.00 78.34  ? 457 ALA E O   1 
ATOM   13486 C CB  . ALA E 2 662 ? 149.970 126.318 90.629  1.00 78.34  ? 457 ALA E CB  1 
ATOM   13487 N N   . LEU E 2 663 ? 148.028 128.034 92.606  1.00 79.81  ? 458 LEU E N   1 
ATOM   13488 C CA  . LEU E 2 663 ? 147.971 129.172 93.512  1.00 79.81  ? 458 LEU E CA  1 
ATOM   13489 C C   . LEU E 2 663 ? 147.296 128.829 94.837  1.00 79.81  ? 458 LEU E C   1 
ATOM   13490 O O   . LEU E 2 663 ? 147.741 129.290 95.894  1.00 79.81  ? 458 LEU E O   1 
ATOM   13491 C CB  . LEU E 2 663 ? 147.248 130.339 92.838  1.00 79.81  ? 458 LEU E CB  1 
ATOM   13492 C CG  . LEU E 2 663 ? 147.543 131.731 93.397  1.00 79.81  ? 458 LEU E CG  1 
ATOM   13493 C CD1 . LEU E 2 663 ? 147.711 132.736 92.269  1.00 79.81  ? 458 LEU E CD1 1 
ATOM   13494 C CD2 . LEU E 2 663 ? 146.440 132.171 94.346  1.00 79.81  ? 458 LEU E CD2 1 
ATOM   13495 N N   . PHE E 2 664 ? 146.224 128.038 94.805  1.00 79.46  ? 459 PHE E N   1 
ATOM   13496 C CA  . PHE E 2 664 ? 145.437 127.822 96.017  1.00 79.46  ? 459 PHE E CA  1 
ATOM   13497 C C   . PHE E 2 664 ? 146.218 127.185 97.160  1.00 79.46  ? 459 PHE E C   1 
ATOM   13498 O O   . PHE E 2 664 ? 146.068 127.657 98.302  1.00 79.46  ? 459 PHE E O   1 
ATOM   13499 C CB  . PHE E 2 664 ? 144.168 127.021 95.692  1.00 79.46  ? 459 PHE E CB  1 
ATOM   13500 C CG  . PHE E 2 664 ? 143.088 127.845 95.053  1.00 79.46  ? 459 PHE E CG  1 
ATOM   13501 C CD1 . PHE E 2 664 ? 143.301 129.184 94.764  1.00 79.46  ? 459 PHE E CD1 1 
ATOM   13502 C CD2 . PHE E 2 664 ? 141.852 127.297 94.777  1.00 79.46  ? 459 PHE E CD2 1 
ATOM   13503 C CE1 . PHE E 2 664 ? 142.310 129.948 94.185  1.00 79.46  ? 459 PHE E CE1 1 
ATOM   13504 C CE2 . PHE E 2 664 ? 140.856 128.058 94.200  1.00 79.46  ? 459 PHE E CE2 1 
ATOM   13505 C CZ  . PHE E 2 664 ? 141.087 129.386 93.903  1.00 79.46  ? 459 PHE E CZ  1 
ATOM   13506 N N   . PRO E 2 665 ? 147.031 126.143 96.956  1.00 77.83  ? 460 PRO E N   1 
ATOM   13507 C CA  . PRO E 2 665 ? 147.878 125.676 98.068  1.00 77.83  ? 460 PRO E CA  1 
ATOM   13508 C C   . PRO E 2 665 ? 148.782 126.764 98.615  1.00 77.83  ? 460 PRO E C   1 
ATOM   13509 O O   . PRO E 2 665 ? 148.985 126.841 99.832  1.00 77.83  ? 460 PRO E O   1 
ATOM   13510 C CB  . PRO E 2 665 ? 148.677 124.532 97.434  1.00 77.83  ? 460 PRO E CB  1 
ATOM   13511 C CG  . PRO E 2 665 ? 147.806 124.041 96.338  1.00 77.83  ? 460 PRO E CG  1 
ATOM   13512 C CD  . PRO E 2 665 ? 147.140 125.256 95.785  1.00 77.83  ? 460 PRO E CD  1 
ATOM   13513 N N   . PHE E 2 666 ? 149.317 127.625 97.744  1.00 78.02  ? 461 PHE E N   1 
ATOM   13514 C CA  . PHE E 2 666 ? 150.221 128.676 98.201  1.00 78.02  ? 461 PHE E CA  1 
ATOM   13515 C C   . PHE E 2 666 ? 149.499 129.690 99.080  1.00 78.02  ? 461 PHE E C   1 
ATOM   13516 O O   . PHE E 2 666 ? 150.009 130.068 100.142 1.00 78.02  ? 461 PHE E O   1 
ATOM   13517 C CB  . PHE E 2 666 ? 150.858 129.376 97.001  1.00 78.02  ? 461 PHE E CB  1 
ATOM   13518 C CG  . PHE E 2 666 ? 151.183 130.825 97.243  1.00 78.02  ? 461 PHE E CG  1 
ATOM   13519 C CD1 . PHE E 2 666 ? 152.236 131.185 98.067  1.00 78.02  ? 461 PHE E CD1 1 
ATOM   13520 C CD2 . PHE E 2 666 ? 150.425 131.825 96.659  1.00 78.02  ? 461 PHE E CD2 1 
ATOM   13521 C CE1 . PHE E 2 666 ? 152.537 132.516 98.290  1.00 78.02  ? 461 PHE E CE1 1 
ATOM   13522 C CE2 . PHE E 2 666 ? 150.718 133.159 96.881  1.00 78.02  ? 461 PHE E CE2 1 
ATOM   13523 C CZ  . PHE E 2 666 ? 151.776 133.505 97.697  1.00 78.02  ? 461 PHE E CZ  1 
ATOM   13524 N N   . CYS E 2 667 ? 148.320 130.155 98.656  1.00 75.89  ? 462 CYS E N   1 
ATOM   13525 C CA  . CYS E 2 667 ? 147.609 131.144 99.461  1.00 75.89  ? 462 CYS E CA  1 
ATOM   13526 C C   . CYS E 2 667 ? 147.087 130.529 100.749 1.00 75.89  ? 462 CYS E C   1 
ATOM   13527 O O   . CYS E 2 667 ? 147.049 131.197 101.787 1.00 75.89  ? 462 CYS E O   1 
ATOM   13528 C CB  . CYS E 2 667 ? 146.468 131.792 98.677  1.00 75.89  ? 462 CYS E CB  1 
ATOM   13529 S SG  . CYS E 2 667 ? 145.431 130.698 97.723  1.00 75.89  ? 462 CYS E SG  1 
ATOM   13530 N N   . PHE E 2 668 ? 146.670 129.261 100.706 1.00 69.04  ? 463 PHE E N   1 
ATOM   13531 C CA  . PHE E 2 668 ? 146.305 128.590 101.948 1.00 69.04  ? 463 PHE E CA  1 
ATOM   13532 C C   . PHE E 2 668 ? 147.492 128.504 102.899 1.00 69.04  ? 463 PHE E C   1 
ATOM   13533 O O   . PHE E 2 668 ? 147.341 128.724 104.104 1.00 69.04  ? 463 PHE E O   1 
ATOM   13534 C CB  . PHE E 2 668 ? 145.749 127.196 101.667 1.00 69.04  ? 463 PHE E CB  1 
ATOM   13535 C CG  . PHE E 2 668 ? 145.245 126.488 102.897 1.00 69.04  ? 463 PHE E CG  1 
ATOM   13536 C CD1 . PHE E 2 668 ? 146.096 125.698 103.654 1.00 69.04  ? 463 PHE E CD1 1 
ATOM   13537 C CD2 . PHE E 2 668 ? 143.928 126.618 103.302 1.00 69.04  ? 463 PHE E CD2 1 
ATOM   13538 C CE1 . PHE E 2 668 ? 145.642 125.056 104.785 1.00 69.04  ? 463 PHE E CE1 1 
ATOM   13539 C CE2 . PHE E 2 668 ? 143.469 125.976 104.432 1.00 69.04  ? 463 PHE E CE2 1 
ATOM   13540 C CZ  . PHE E 2 668 ? 144.325 125.195 105.174 1.00 69.04  ? 463 PHE E CZ  1 
ATOM   13541 N N   . LEU E 2 669 ? 148.678 128.174 102.381 1.00 67.86  ? 464 LEU E N   1 
ATOM   13542 C CA  . LEU E 2 669 ? 149.861 128.116 103.234 1.00 67.86  ? 464 LEU E CA  1 
ATOM   13543 C C   . LEU E 2 669 ? 150.182 129.484 103.819 1.00 67.86  ? 464 LEU E C   1 
ATOM   13544 O O   . LEU E 2 669 ? 150.522 129.600 105.003 1.00 67.86  ? 464 LEU E O   1 
ATOM   13545 C CB  . LEU E 2 669 ? 151.053 127.580 102.443 1.00 67.86  ? 464 LEU E CB  1 
ATOM   13546 C CG  . LEU E 2 669 ? 152.405 127.675 103.152 1.00 67.86  ? 464 LEU E CG  1 
ATOM   13547 C CD1 . LEU E 2 669 ? 152.431 126.777 104.381 1.00 67.86  ? 464 LEU E CD1 1 
ATOM   13548 C CD2 . LEU E 2 669 ? 153.543 127.335 102.206 1.00 67.86  ? 464 LEU E CD2 1 
ATOM   13549 N N   . PHE E 2 670 ? 150.080 130.532 103.001 1.00 70.22  ? 465 PHE E N   1 
ATOM   13550 C CA  . PHE E 2 670 ? 150.346 131.882 103.488 1.00 70.22  ? 465 PHE E CA  1 
ATOM   13551 C C   . PHE E 2 670 ? 149.350 132.280 104.571 1.00 70.22  ? 465 PHE E C   1 
ATOM   13552 O O   . PHE E 2 670 ? 149.735 132.846 105.604 1.00 70.22  ? 465 PHE E O   1 
ATOM   13553 C CB  . PHE E 2 670 ? 150.313 132.866 102.317 1.00 70.22  ? 465 PHE E CB  1 
ATOM   13554 C CG  . PHE E 2 670 ? 149.658 134.179 102.638 1.00 70.22  ? 465 PHE E CG  1 
ATOM   13555 C CD1 . PHE E 2 670 ? 150.350 135.167 103.320 1.00 70.22  ? 465 PHE E CD1 1 
ATOM   13556 C CD2 . PHE E 2 670 ? 148.355 134.432 102.243 1.00 70.22  ? 465 PHE E CD2 1 
ATOM   13557 C CE1 . PHE E 2 670 ? 149.750 136.377 103.610 1.00 70.22  ? 465 PHE E CE1 1 
ATOM   13558 C CE2 . PHE E 2 670 ? 147.750 135.638 102.530 1.00 70.22  ? 465 PHE E CE2 1 
ATOM   13559 C CZ  . PHE E 2 670 ? 148.448 136.613 103.214 1.00 70.22  ? 465 PHE E CZ  1 
ATOM   13560 N N   . PHE E 2 671 ? 148.066 131.981 104.359 1.00 65.85  ? 466 PHE E N   1 
ATOM   13561 C CA  . PHE E 2 671 ? 147.060 132.287 105.369 1.00 65.85  ? 466 PHE E CA  1 
ATOM   13562 C C   . PHE E 2 671 ? 147.312 131.506 106.649 1.00 65.85  ? 466 PHE E C   1 
ATOM   13563 O O   . PHE E 2 671 ? 147.193 132.054 107.748 1.00 65.85  ? 466 PHE E O   1 
ATOM   13564 C CB  . PHE E 2 671 ? 145.661 131.989 104.835 1.00 65.85  ? 466 PHE E CB  1 
ATOM   13565 C CG  . PHE E 2 671 ? 144.671 131.654 105.909 1.00 65.85  ? 466 PHE E CG  1 
ATOM   13566 C CD1 . PHE E 2 671 ? 144.146 132.645 106.717 1.00 65.85  ? 466 PHE E CD1 1 
ATOM   13567 C CD2 . PHE E 2 671 ? 144.271 130.346 106.116 1.00 65.85  ? 466 PHE E CD2 1 
ATOM   13568 C CE1 . PHE E 2 671 ? 143.241 132.339 107.710 1.00 65.85  ? 466 PHE E CE1 1 
ATOM   13569 C CE2 . PHE E 2 671 ? 143.366 130.035 107.107 1.00 65.85  ? 466 PHE E CE2 1 
ATOM   13570 C CZ  . PHE E 2 671 ? 142.852 131.032 107.905 1.00 65.85  ? 466 PHE E CZ  1 
ATOM   13571 N N   . ASN E 2 672 ? 147.654 130.223 106.529 1.00 65.36  ? 467 ASN E N   1 
ATOM   13572 C CA  . ASN E 2 672 ? 147.925 129.419 107.714 1.00 65.36  ? 467 ASN E CA  1 
ATOM   13573 C C   . ASN E 2 672 ? 149.113 129.972 108.485 1.00 65.36  ? 467 ASN E C   1 
ATOM   13574 O O   . ASN E 2 672 ? 149.068 130.082 109.716 1.00 65.36  ? 467 ASN E O   1 
ATOM   13575 C CB  . ASN E 2 672 ? 148.170 127.963 107.312 1.00 65.36  ? 467 ASN E CB  1 
ATOM   13576 C CG  . ASN E 2 672 ? 148.364 127.049 108.507 1.00 65.36  ? 467 ASN E CG  1 
ATOM   13577 O OD1 . ASN E 2 672 ? 147.995 127.388 109.631 1.00 65.36  ? 467 ASN E OD1 1 
ATOM   13578 N ND2 . ASN E 2 672 ? 148.944 125.880 108.267 1.00 65.36  ? 467 ASN E ND2 1 
ATOM   13579 N N   . VAL E 2 673 ? 150.175 130.354 107.774 1.00 63.70  ? 468 VAL E N   1 
ATOM   13580 C CA  . VAL E 2 673 ? 151.364 130.882 108.434 1.00 63.70  ? 468 VAL E CA  1 
ATOM   13581 C C   . VAL E 2 673 ? 151.036 132.181 109.158 1.00 63.70  ? 468 VAL E C   1 
ATOM   13582 O O   . VAL E 2 673 ? 151.374 132.355 110.336 1.00 63.70  ? 468 VAL E O   1 
ATOM   13583 C CB  . VAL E 2 673 ? 152.502 131.073 107.417 1.00 63.70  ? 468 VAL E CB  1 
ATOM   13584 C CG1 . VAL E 2 673 ? 153.567 132.000 107.980 1.00 63.70  ? 468 VAL E CG1 1 
ATOM   13585 C CG2 . VAL E 2 673 ? 153.103 129.730 107.043 1.00 63.70  ? 468 VAL E CG2 1 
ATOM   13586 N N   . ILE E 2 674 ? 150.359 133.108 108.474 1.00 59.95  ? 469 ILE E N   1 
ATOM   13587 C CA  . ILE E 2 674 ? 150.083 134.402 109.093 1.00 59.95  ? 469 ILE E CA  1 
ATOM   13588 C C   . ILE E 2 674 ? 149.117 134.244 110.262 1.00 59.95  ? 469 ILE E C   1 
ATOM   13589 O O   . ILE E 2 674 ? 149.286 134.879 111.310 1.00 59.95  ? 469 ILE E O   1 
ATOM   13590 C CB  . ILE E 2 674 ? 149.573 135.415 108.048 1.00 59.95  ? 469 ILE E CB  1 
ATOM   13591 C CG1 . ILE E 2 674 ? 149.496 136.815 108.659 1.00 59.95  ? 469 ILE E CG1 1 
ATOM   13592 C CG2 . ILE E 2 674 ? 148.222 135.016 107.489 1.00 59.95  ? 469 ILE E CG2 1 
ATOM   13593 C CD1 . ILE E 2 674 ? 149.085 137.889 107.676 1.00 59.95  ? 469 ILE E CD1 1 
ATOM   13594 N N   . TYR E 2 675 ? 148.114 133.373 110.123 1.00 59.26  ? 470 TYR E N   1 
ATOM   13595 C CA  . TYR E 2 675 ? 147.146 133.165 111.192 1.00 59.26  ? 470 TYR E CA  1 
ATOM   13596 C C   . TYR E 2 675 ? 147.805 132.551 112.419 1.00 59.26  ? 470 TYR E C   1 
ATOM   13597 O O   . TYR E 2 675 ? 147.588 133.013 113.545 1.00 59.26  ? 470 TYR E O   1 
ATOM   13598 C CB  . TYR E 2 675 ? 146.004 132.283 110.685 1.00 59.26  ? 470 TYR E CB  1 
ATOM   13599 C CG  . TYR E 2 675 ? 145.206 131.584 111.761 1.00 59.26  ? 470 TYR E CG  1 
ATOM   13600 C CD1 . TYR E 2 675 ? 144.188 132.241 112.434 1.00 59.26  ? 470 TYR E CD1 1 
ATOM   13601 C CD2 . TYR E 2 675 ? 145.458 130.259 112.087 1.00 59.26  ? 470 TYR E CD2 1 
ATOM   13602 C CE1 . TYR E 2 675 ? 143.451 131.602 113.410 1.00 59.26  ? 470 TYR E CE1 1 
ATOM   13603 C CE2 . TYR E 2 675 ? 144.728 129.614 113.061 1.00 59.26  ? 470 TYR E CE2 1 
ATOM   13604 C CZ  . TYR E 2 675 ? 143.726 130.289 113.719 1.00 59.26  ? 470 TYR E CZ  1 
ATOM   13605 O OH  . TYR E 2 675 ? 142.996 129.647 114.692 1.00 59.26  ? 470 TYR E OH  1 
ATOM   13606 N N   . TRP E 2 676 ? 148.614 131.506 112.224 1.00 57.81  ? 471 TRP E N   1 
ATOM   13607 C CA  . TRP E 2 676 ? 149.270 130.877 113.363 1.00 57.81  ? 471 TRP E CA  1 
ATOM   13608 C C   . TRP E 2 676 ? 150.268 131.820 114.020 1.00 57.81  ? 471 TRP E C   1 
ATOM   13609 O O   . TRP E 2 676 ? 150.370 131.857 115.251 1.00 57.81  ? 471 TRP E O   1 
ATOM   13610 C CB  . TRP E 2 676 ? 149.947 129.578 112.935 1.00 57.81  ? 471 TRP E CB  1 
ATOM   13611 C CG  . TRP E 2 676 ? 149.196 128.365 113.377 1.00 57.81  ? 471 TRP E CG  1 
ATOM   13612 C CD1 . TRP E 2 676 ? 147.878 128.300 113.721 1.00 57.81  ? 471 TRP E CD1 1 
ATOM   13613 C CD2 . TRP E 2 676 ? 149.718 127.041 113.540 1.00 57.81  ? 471 TRP E CD2 1 
ATOM   13614 N NE1 . TRP E 2 676 ? 147.545 127.018 114.081 1.00 57.81  ? 471 TRP E NE1 1 
ATOM   13615 C CE2 . TRP E 2 676 ? 148.657 126.225 113.979 1.00 57.81  ? 471 TRP E CE2 1 
ATOM   13616 C CE3 . TRP E 2 676 ? 150.979 126.465 113.353 1.00 57.81  ? 471 TRP E CE3 1 
ATOM   13617 C CZ2 . TRP E 2 676 ? 148.817 124.864 114.234 1.00 57.81  ? 471 TRP E CZ2 1 
ATOM   13618 C CZ3 . TRP E 2 676 ? 151.136 125.113 113.608 1.00 57.81  ? 471 TRP E CZ3 1 
ATOM   13619 C CH2 . TRP E 2 676 ? 150.061 124.329 114.044 1.00 57.81  ? 471 TRP E CH2 1 
ATOM   13620 N N   . SER E 2 677 ? 151.007 132.597 113.225 1.00 61.03  ? 472 SER E N   1 
ATOM   13621 C CA  . SER E 2 677 ? 151.945 133.548 113.810 1.00 61.03  ? 472 SER E CA  1 
ATOM   13622 C C   . SER E 2 677 ? 151.220 134.624 114.607 1.00 61.03  ? 472 SER E C   1 
ATOM   13623 O O   . SER E 2 677 ? 151.676 135.021 115.686 1.00 61.03  ? 472 SER E O   1 
ATOM   13624 C CB  . SER E 2 677 ? 152.804 134.180 112.717 1.00 61.03  ? 472 SER E CB  1 
ATOM   13625 O OG  . SER E 2 677 ? 153.661 135.171 113.257 1.00 61.03  ? 472 SER E OG  1 
ATOM   13626 N N   . ILE E 2 678 ? 150.091 135.116 114.091 1.00 58.31  ? 473 ILE E N   1 
ATOM   13627 C CA  . ILE E 2 678 ? 149.373 136.187 114.772 1.00 58.31  ? 473 ILE E CA  1 
ATOM   13628 C C   . ILE E 2 678 ? 148.713 135.671 116.047 1.00 58.31  ? 473 ILE E C   1 
ATOM   13629 O O   . ILE E 2 678 ? 148.747 136.335 117.089 1.00 58.31  ? 473 ILE E O   1 
ATOM   13630 C CB  . ILE E 2 678 ? 148.352 136.827 113.813 1.00 58.31  ? 473 ILE E CB  1 
ATOM   13631 C CG1 . ILE E 2 678 ? 149.028 137.901 112.960 1.00 58.31  ? 473 ILE E CG1 1 
ATOM   13632 C CG2 . ILE E 2 678 ? 147.196 137.439 114.579 1.00 58.31  ? 473 ILE E CG2 1 
ATOM   13633 C CD1 . ILE E 2 678 ? 149.417 139.141 113.732 1.00 58.31  ? 473 ILE E CD1 1 
ATOM   13634 N N   . TYR E 2 679 ? 148.122 134.478 115.995 1.00 54.74  ? 474 TYR E N   1 
ATOM   13635 C CA  . TYR E 2 679 ? 147.310 133.964 117.088 1.00 54.74  ? 474 TYR E CA  1 
ATOM   13636 C C   . TYR E 2 679 ? 148.030 132.919 117.932 1.00 54.74  ? 474 TYR E C   1 
ATOM   13637 O O   . TYR E 2 679 ? 147.378 132.221 118.715 1.00 54.74  ? 474 TYR E O   1 
ATOM   13638 C CB  . TYR E 2 679 ? 146.010 133.383 116.533 1.00 54.74  ? 474 TYR E CB  1 
ATOM   13639 C CG  . TYR E 2 679 ? 144.867 134.365 116.542 1.00 54.74  ? 474 TYR E CG  1 
ATOM   13640 C CD1 . TYR E 2 679 ? 145.097 135.718 116.730 1.00 54.74  ? 474 TYR E CD1 1 
ATOM   13641 C CD2 . TYR E 2 679 ? 143.564 133.947 116.334 1.00 54.74  ? 474 TYR E CD2 1 
ATOM   13642 C CE1 . TYR E 2 679 ? 144.059 136.626 116.732 1.00 54.74  ? 474 TYR E CE1 1 
ATOM   13643 C CE2 . TYR E 2 679 ? 142.518 134.848 116.332 1.00 54.74  ? 474 TYR E CE2 1 
ATOM   13644 C CZ  . TYR E 2 679 ? 142.771 136.185 116.532 1.00 54.74  ? 474 TYR E CZ  1 
ATOM   13645 O OH  . TYR E 2 679 ? 141.733 137.088 116.533 1.00 54.74  ? 474 TYR E OH  1 
ATOM   13646 N N   . LEU E 2 680 ? 149.347 132.792 117.786 1.00 57.78  ? 475 LEU E N   1 
ATOM   13647 C CA  . LEU E 2 680 ? 150.146 131.873 118.594 1.00 57.78  ? 475 LEU E CA  1 
ATOM   13648 C C   . LEU E 2 680 ? 149.644 130.436 118.492 1.00 57.78  ? 475 LEU E C   1 
ATOM   13649 O O   . LEU E 2 680 ? 150.378 129.490 118.777 1.00 57.78  ? 475 LEU E O   1 
ATOM   13650 C CB  . LEU E 2 680 ? 150.165 132.318 120.060 1.00 57.78  ? 475 LEU E CB  1 
ATOM   13651 C CG  . LEU E 2 680 ? 150.992 133.560 120.405 1.00 57.78  ? 475 LEU E CG  1 
ATOM   13652 C CD1 . LEU E 2 680 ? 152.317 133.560 119.650 1.00 57.78  ? 475 LEU E CD1 1 
ATOM   13653 C CD2 . LEU E 2 680 ? 150.213 134.843 120.145 1.00 57.78  ? 475 LEU E CD2 1 
HETATM 13654 C C1  . NAG F 3 .   ? 107.735 158.525 157.625 1.00 50.78  ? 501 NAG A C1  1 
HETATM 13655 C C2  . NAG F 3 .   ? 107.318 159.650 158.585 1.00 50.78  ? 501 NAG A C2  1 
HETATM 13656 C C3  . NAG F 3 .   ? 105.846 159.998 158.371 1.00 50.78  ? 501 NAG A C3  1 
HETATM 13657 C C4  . NAG F 3 .   ? 105.609 160.344 156.908 1.00 50.78  ? 501 NAG A C4  1 
HETATM 13658 C C5  . NAG F 3 .   ? 106.139 159.212 156.022 1.00 50.78  ? 501 NAG A C5  1 
HETATM 13659 C C6  . NAG F 3 .   ? 106.008 159.501 154.543 1.00 50.78  ? 501 NAG A C6  1 
HETATM 13660 C C7  . NAG F 3 .   ? 106.984 158.644 160.887 1.00 50.78  ? 501 NAG A C7  1 
HETATM 13661 C C8  . NAG F 3 .   ? 107.687 158.552 162.219 1.00 50.78  ? 501 NAG A C8  1 
HETATM 13662 N N2  . NAG F 3 .   ? 107.664 159.349 159.957 1.00 50.78  ? 501 NAG A N2  1 
HETATM 13663 O O3  . NAG F 3 .   ? 105.523 161.064 159.224 1.00 50.78  ? 501 NAG A O3  1 
HETATM 13664 O O4  . NAG F 3 .   ? 104.223 160.533 156.742 1.00 50.78  ? 501 NAG A O4  1 
HETATM 13665 O O5  . NAG F 3 .   ? 107.503 158.980 156.312 1.00 50.78  ? 501 NAG A O5  1 
HETATM 13666 O O6  . NAG F 3 .   ? 106.591 160.750 154.254 1.00 50.78  ? 501 NAG A O6  1 
HETATM 13667 O O7  . NAG F 3 .   ? 105.901 158.104 160.721 1.00 50.78  ? 501 NAG A O7  1 
HETATM 13668 N N   . GLY G 4 .   ? 124.276 141.959 152.999 1.00 44.60  ? 502 GLY A N   1 
HETATM 13669 C CA  . GLY G 4 .   ? 124.338 142.566 151.683 1.00 44.60  ? 502 GLY A CA  1 
HETATM 13670 C C   . GLY G 4 .   ? 123.034 143.195 151.248 1.00 44.60  ? 502 GLY A C   1 
HETATM 13671 O O   . GLY G 4 .   ? 122.623 144.227 151.760 1.00 44.60  ? 502 GLY A O   1 
HETATM 13672 O OXT . GLY G 4 .   ? 122.354 142.693 150.359 1.00 44.60  ? 502 GLY A OXT 1 
HETATM 13673 C C1  . NAG H 3 .   ? 80.886  125.455 159.807 1.00 54.14  ? 501 NAG B C1  1 
HETATM 13674 C C2  . NAG H 3 .   ? 79.964  126.250 160.758 1.00 54.14  ? 501 NAG B C2  1 
HETATM 13675 C C3  . NAG H 3 .   ? 79.136  125.341 161.669 1.00 54.14  ? 501 NAG B C3  1 
HETATM 13676 C C4  . NAG H 3 .   ? 78.444  124.255 160.870 1.00 54.14  ? 501 NAG B C4  1 
HETATM 13677 C C5  . NAG H 3 .   ? 79.527  123.480 160.131 1.00 54.14  ? 501 NAG B C5  1 
HETATM 13678 C C6  . NAG H 3 .   ? 78.975  122.336 159.315 1.00 54.14  ? 501 NAG B C6  1 
HETATM 13679 C C7  . NAG H 3 .   ? 81.473  126.983 162.636 1.00 54.14  ? 501 NAG B C7  1 
HETATM 13680 C C8  . NAG H 3 .   ? 82.077  128.227 163.240 1.00 54.14  ? 501 NAG B C8  1 
HETATM 13681 N N2  . NAG H 3 .   ? 80.686  127.211 161.559 1.00 54.14  ? 501 NAG B N2  1 
HETATM 13682 O O3  . NAG H 3 .   ? 78.224  126.145 162.368 1.00 54.14  ? 501 NAG B O3  1 
HETATM 13683 O O4  . NAG H 3 .   ? 77.752  123.438 161.784 1.00 54.14  ? 501 NAG B O4  1 
HETATM 13684 O O5  . NAG H 3 .   ? 80.190  124.361 159.251 1.00 54.14  ? 501 NAG B O5  1 
HETATM 13685 O O6  . NAG H 3 .   ? 78.005  122.827 158.420 1.00 54.14  ? 501 NAG B O6  1 
HETATM 13686 O O7  . NAG H 3 .   ? 81.718  125.885 163.115 1.00 54.14  ? 501 NAG B O7  1 
HETATM 13687 N N   . GLY I 4 .   ? 94.856  110.989 153.861 1.00 37.82  ? 502 GLY B N   1 
HETATM 13688 C CA  . GLY I 4 .   ? 95.092  109.574 154.066 1.00 37.82  ? 502 GLY B CA  1 
HETATM 13689 C C   . GLY I 4 .   ? 95.400  109.216 155.504 1.00 37.82  ? 502 GLY B C   1 
HETATM 13690 O O   . GLY I 4 .   ? 95.522  110.090 156.361 1.00 37.82  ? 502 GLY B O   1 
HETATM 13691 O OXT . GLY I 4 .   ? 95.539  108.042 155.846 1.00 37.82  ? 502 GLY B OXT 1 
HETATM 13692 C C1  . NAG J 3 .   ? 103.827 91.021  167.723 1.00 56.20  ? 501 NAG C C1  1 
HETATM 13693 C C2  . NAG J 3 .   ? 103.307 90.181  168.900 1.00 56.20  ? 501 NAG C C2  1 
HETATM 13694 C C3  . NAG J 3 .   ? 104.355 89.151  169.308 1.00 56.20  ? 501 NAG C C3  1 
HETATM 13695 C C4  . NAG J 3 .   ? 104.694 88.286  168.104 1.00 56.20  ? 501 NAG C C4  1 
HETATM 13696 C C5  . NAG J 3 .   ? 105.111 89.183  166.934 1.00 56.20  ? 501 NAG C C5  1 
HETATM 13697 C C6  . NAG J 3 .   ? 105.391 88.410  165.665 1.00 56.20  ? 501 NAG C C6  1 
HETATM 13698 C C7  . NAG J 3 .   ? 103.591 91.726  170.859 1.00 56.20  ? 501 NAG C C7  1 
HETATM 13699 C C8  . NAG J 3 .   ? 102.790 92.456  171.908 1.00 56.20  ? 501 NAG C C8  1 
HETATM 13700 N N2  . NAG J 3 .   ? 102.851 90.991  170.006 1.00 56.20  ? 501 NAG C N2  1 
HETATM 13701 O O3  . NAG J 3 .   ? 103.835 88.395  170.367 1.00 56.20  ? 501 NAG C O3  1 
HETATM 13702 O O4  . NAG J 3 .   ? 105.729 87.415  168.494 1.00 56.20  ? 501 NAG C O4  1 
HETATM 13703 O O5  . NAG J 3 .   ? 104.093 90.130  166.664 1.00 56.20  ? 501 NAG C O5  1 
HETATM 13704 O O6  . NAG J 3 .   ? 104.316 87.541  165.395 1.00 56.20  ? 501 NAG C O6  1 
HETATM 13705 O O7  . NAG J 3 .   ? 104.807 91.821  170.821 1.00 56.20  ? 501 NAG C O7  1 
HETATM 13706 C C1  . NAG K 3 .   ? 144.120 102.219 170.059 1.00 48.99  ? 501 NAG D C1  1 
HETATM 13707 C C2  . NAG K 3 .   ? 144.667 101.767 171.423 1.00 48.99  ? 501 NAG D C2  1 
HETATM 13708 C C3  . NAG K 3 .   ? 145.973 102.492 171.737 1.00 48.99  ? 501 NAG D C3  1 
HETATM 13709 C C4  . NAG K 3 .   ? 146.959 102.296 170.594 1.00 48.99  ? 501 NAG D C4  1 
HETATM 13710 C C5  . NAG K 3 .   ? 146.296 102.724 169.281 1.00 48.99  ? 501 NAG D C5  1 
HETATM 13711 C C6  . NAG K 3 .   ? 147.183 102.539 168.071 1.00 48.99  ? 501 NAG D C6  1 
HETATM 13712 C C7  . NAG K 3 .   ? 143.192 103.062 172.980 1.00 48.99  ? 501 NAG D C7  1 
HETATM 13713 C C8  . NAG K 3 .   ? 142.194 102.876 174.096 1.00 48.99  ? 501 NAG D C8  1 
HETATM 13714 N N2  . NAG K 3 .   ? 143.700 101.915 172.485 1.00 48.99  ? 501 NAG D N2  1 
HETATM 13715 O O3  . NAG K 3 .   ? 146.464 101.985 172.948 1.00 48.99  ? 501 NAG D O3  1 
HETATM 13716 O O4  . NAG K 3 .   ? 148.101 103.068 170.885 1.00 48.99  ? 501 NAG D O4  1 
HETATM 13717 O O5  . NAG K 3 .   ? 145.115 101.971 169.091 1.00 48.99  ? 501 NAG D O5  1 
HETATM 13718 O O6  . NAG K 3 .   ? 147.683 101.224 168.053 1.00 48.99  ? 501 NAG D O6  1 
HETATM 13719 O O7  . NAG K 3 .   ? 143.485 104.179 172.585 1.00 48.99  ? 501 NAG D O7  1 
HETATM 13720 N N   . GLY L 4 .   ? 127.025 105.099 168.883 1.00 53.68  ? 502 GLY D N   1 
HETATM 13721 C CA  . GLY L 4 .   ? 126.279 104.132 168.102 1.00 53.68  ? 502 GLY D CA  1 
HETATM 13722 C C   . GLY L 4 .   ? 126.508 102.683 168.491 1.00 53.68  ? 502 GLY D C   1 
HETATM 13723 O O   . GLY L 4 .   ? 127.529 102.300 169.050 1.00 53.68  ? 502 GLY D O   1 
HETATM 13724 O OXT . GLY L 4 .   ? 125.688 101.809 168.229 1.00 53.68  ? 502 GLY D OXT 1 
HETATM 13725 C C1  . NAG M 3 .   ? 145.295 146.327 152.005 1.00 65.74  ? 501 NAG E C1  1 
HETATM 13726 C C2  . NAG M 3 .   ? 146.771 146.248 152.405 1.00 65.74  ? 501 NAG E C2  1 
HETATM 13727 C C3  . NAG M 3 .   ? 147.065 147.417 153.339 1.00 65.74  ? 501 NAG E C3  1 
HETATM 13728 C C4  . NAG M 3 .   ? 146.632 148.740 152.713 1.00 65.74  ? 501 NAG E C4  1 
HETATM 13729 C C5  . NAG M 3 .   ? 145.201 148.640 152.168 1.00 65.74  ? 501 NAG E C5  1 
HETATM 13730 C C6  . NAG M 3 .   ? 144.736 149.886 151.448 1.00 65.74  ? 501 NAG E C6  1 
HETATM 13731 C C7  . NAG M 3 .   ? 148.058 144.168 152.676 1.00 65.74  ? 501 NAG E C7  1 
HETATM 13732 C C8  . NAG M 3 .   ? 148.184 142.911 153.501 1.00 65.74  ? 501 NAG E C8  1 
HETATM 13733 N N2  . NAG M 3 .   ? 147.069 144.999 153.050 1.00 65.74  ? 501 NAG E N2  1 
HETATM 13734 O O3  . NAG M 3 .   ? 148.436 147.398 153.636 1.00 65.74  ? 501 NAG E O3  1 
HETATM 13735 O O4  . NAG M 3 .   ? 146.723 149.721 153.721 1.00 65.74  ? 501 NAG E O4  1 
HETATM 13736 O O5  . NAG M 3 .   ? 145.097 147.527 151.299 1.00 65.74  ? 501 NAG E O5  1 
HETATM 13737 O O6  . NAG M 3 .   ? 144.596 150.936 152.375 1.00 65.74  ? 501 NAG E O6  1 
HETATM 13738 O O7  . NAG M 3 .   ? 148.809 144.397 151.741 1.00 65.74  ? 501 NAG E O7  1 
HETATM 13739 N N   . GLY N 4 .   ? 142.330 121.076 158.514 1.00 33.62  ? 502 GLY E N   1 
HETATM 13740 C CA  . GLY N 4 .   ? 142.420 121.873 157.305 1.00 33.62  ? 502 GLY E CA  1 
HETATM 13741 C C   . GLY N 4 .   ? 143.711 122.658 157.212 1.00 33.62  ? 502 GLY E C   1 
HETATM 13742 O O   . GLY N 4 .   ? 144.408 122.838 158.208 1.00 33.62  ? 502 GLY E O   1 
HETATM 13743 O OXT . GLY N 4 .   ? 144.093 123.132 156.144 1.00 33.62  ? 502 GLY E OXT 1 
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